LOCUS       DAFGPF010000001       133862 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFGPF010000001 DAFGPF010000000
VERSION     DAFGPF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 133862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 133862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..133862
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.001"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            213..3200
                     /locus_tag="LSX49_000001"
     CDS             213..3200
                     /locus_tag="LSX49_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000556401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7166478.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANAANYDTWGYHDNTTTDLV
                     WPYDTDNDGIADAGGMDPMGSDGNYVTYNGFVYYNNANGDFDTVFKGDTVNGTISTYY
                     LNHDYASGSVNQLDISNSVIHGSITSELPFGYYSITPAEVNAKGEVVTPQTYSGYNFY
                     NGITTDLDYNWYDGDVFTLNVSNSTIDDDYEALYFTDTYLDGDKSKSTNETFYTALGV
                     AVNLDVESNINITNNSRVAGIALSEGNTSNTTYTSEYHQWDNNINVSNSTVTSGSQTP
                     LEESNGFFGKSAEPSDYAGNGGENDVALSFSDNAGSNYSMKNNVNFDHSTLLGDVEFT
                     SHWNNDGVFFYSTGHDSNGDGVLDTNGGWVDDAQNVDELNITLNNGSKWVGSANMSAE
                     VIAPADMYDVAPNSLTPGATIEANDWGRIIDNKVFQSGVFNVALNNGSEWNTVNSSVI
                     DTLAVNNGSQVNVTDSSLVSDTIGLTNGSSLNIGEDGLVATDHLTVDSYSTVNLTEST
                     GWNNYSNLYANTITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSGVFD
                     INSSDYVLNADLVNDRTWDTSKSNYGYGIVAMNSDGHLTINGNGDVDNGTELDNSSVD
                     NVVAATGNYKVRIDNATGAGAIADYKDKEIIYVNDKNSNATFSAANKADLGAYTYQAE
                     QRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVS
                     YFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVD
                     QDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKA
                     GYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNNMKVDGQSYDSMRYELGVDAGYTFTY
                     SEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTD
                     ANYLGGGDVDQDWSANVGVKYTW"
     gene            3286..3909
                     /gene="iprA"
                     /locus_tag="LSX49_000002"
     CDS             3286..3909
                     /gene="iprA"
                     /locus_tag="LSX49_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HBL7166479.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNSEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     gene            complement(3910..5067)
                     /gene="ampH"
                     /locus_tag="LSX49_000003"
     CDS             complement(3910..5067)
                     /gene="ampH"
                     /locus_tag="LSX49_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HBL7166480.1"
                     /translation="MKRSLLFSAVLYSASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            5419..6639
                     /gene="sbmA"
                     /locus_tag="LSX49_000004"
     CDS             5419..6639
                     /gene="sbmA"
                     /locus_tag="LSX49_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HBL7166481.1"
                     /translation="MFKSFFPKPGMFFLSAFVWALIAVIFWQVGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIVGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRVTPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            6652..7746
                     /gene="yaiW"
                     /locus_tag="LSX49_000005"
     CDS             6652..7746
                     /gene="yaiW"
                     /locus_tag="LSX49_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HBL7166482.1"
                     /translation="MSRVNPLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAGKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(7805..8113)
                     /locus_tag="LSX49_000006"
     CDS             complement(7805..8113)
                     /locus_tag="LSX49_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HBL7166483.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            8373..8585
                     /locus_tag="LSX49_000007"
     CDS             8373..8585
                     /locus_tag="LSX49_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HBL7166484.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            complement(8609..9703)
                     /gene="ddlA"
                     /locus_tag="LSX49_000008"
     CDS             complement(8609..9703)
                     /gene="ddlA"
                     /locus_tag="LSX49_000008"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL7166485.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYTIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNNNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            9781..9984
                     /locus_tag="LSX49_000009"
                     /pseudo
     CDS             9781..9984
                     /locus_tag="LSX49_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439229.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10166..10426
                     /gene="iraP"
                     /locus_tag="LSX49_000010"
     CDS             10166..10426
                     /gene="iraP"
                     /locus_tag="LSX49_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HBL7166486.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLRHPRQ"
     gene            10527..11942
                     /gene="phoA"
                     /locus_tag="LSX49_000011"
     CDS             10527..11942
                     /gene="phoA"
                     /locus_tag="LSX49_000011"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HBL7166487.1"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKP
                     LLGLFADGNMPVRWQGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            12061..12381
                     /gene="psiF"
                     /locus_tag="LSX49_000012"
     CDS             12061..12381
                     /gene="psiF"
                     /locus_tag="LSX49_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HBL7166488.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            12483..13598
                     /gene="adrA"
                     /locus_tag="LSX49_000013"
                     /gene_synonym="dgcC"
     CDS             12483..13598
                     /gene="adrA"
                     /locus_tag="LSX49_000013"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HBL7166489.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(13615..14424)
                     /gene="proC"
                     /locus_tag="LSX49_000014"
     CDS             complement(13615..14424)
                     /gene="proC"
                     /locus_tag="LSX49_000014"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBL7166490.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVTA
                     LHEQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGITL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGTLKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            14544..15002
                     /locus_tag="LSX49_000015"
     CDS             14544..15002
                     /locus_tag="LSX49_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBL7166491.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     gene            15185..15709
                     /gene="aroL"
                     /locus_tag="LSX49_000016"
     CDS             15185..15709
                     /gene="aroL"
                     /locus_tag="LSX49_000016"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HBL7166492.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     gene            15759..15950
                     /gene="yaiA"
                     /locus_tag="LSX49_000017"
     CDS             15759..15950
                     /gene="yaiA"
                     /locus_tag="LSX49_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HBL7166493.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            16208..16885
                     /locus_tag="LSX49_000018"
     CDS             16208..16885
                     /locus_tag="LSX49_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HBL7166494.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSSEE
                     VMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLM"
     gene            16957..17241
                     /gene="ppnP"
                     /locus_tag="LSX49_000019"
     CDS             16957..17241
                     /gene="ppnP"
                     /locus_tag="LSX49_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBL7166495.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            17389..17730
                     /locus_tag="LSX49_000020"
                     /pseudo
     CDS             17389..17730
                     /locus_tag="LSX49_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308469.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing protein"
     gene            17727..17807
                     /locus_tag="LSX49_000021"
     CDS             17727..17807
                     /locus_tag="LSX49_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166496.1"
                     /translation="MTQRPWSKLQHKTHNIAALRIIARCS"
     gene            complement(17888..18799)
                     /gene="rdgC"
                     /locus_tag="LSX49_000022"
     CDS             complement(17888..18799)
                     /gene="rdgC"
                     /locus_tag="LSX49_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HBL7166497.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQVRKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            18924..19832
                     /gene="mak"
                     /locus_tag="LSX49_000023"
     CDS             18924..19832
                     /gene="mak"
                     /locus_tag="LSX49_000023"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308471.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HBL7166498.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVPQLIKQFVFGGE
                     CETPVHKAKHGDSSGVRGAAWLWPQE"
     gene            complement(20101..21285)
                     /gene="araJ"
                     /locus_tag="LSX49_000024"
     CDS             complement(20101..21285)
                     /gene="araJ"
                     /locus_tag="LSX49_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HBL7166499.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAIFNIAVMASVYFWVPDIRDEAKGKLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFFGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADSPVLAKP
                     LG"
     gene            complement(21411..24554)
                     /gene="sbcC"
                     /locus_tag="LSX49_000025"
     CDS             complement(21411..24554)
                     /gene="sbcC"
                     /locus_tag="LSX49_000025"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HBL7166500.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKDEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
                     QSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRLDELQQEASRRQQALQQALAEEEQA
                     QPQLAALSLAQPARNLRPHWERIAEHSTALAHTRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNAWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVASAQAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQ
                     NVTLEQTQRNAALNKMRHRYKEKMQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQARLLTLEKEVKKLGEEGATLRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRMQQLTPILETLPQSDELPHSEETVALENWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLTQHQQHRPGGLSLTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESAFAVK"
     gene            complement(24551..25753)
                     /gene="sbcD"
                     /locus_tag="LSX49_000026"
     CDS             complement(24551..25753)
                     /gene="sbcD"
                     /locus_tag="LSX49_000026"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HBL7166501.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQAHLVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQLIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFATTLH
                     SLAGEHEA"
     gene            25943..26632
                     /gene="phoB"
                     /locus_tag="LSX49_000027"
     CDS             25943..26632
                     /gene="phoB"
                     /locus_tag="LSX49_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HBL7166502.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            26690..27985
                     /gene="phoR"
                     /locus_tag="LSX49_000028"
     CDS             26690..27985
                     /gene="phoR"
                     /locus_tag="LSX49_000028"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HBL7166503.1"
                     /translation="MLERLSWKRLVLELLFCCLPAFILGAFLGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFIIPERLIAKNSD"
     gene            28392..29711
                     /gene="brnQ"
                     /locus_tag="LSX49_000029"
     CDS             28392..29711
                     /gene="brnQ"
                     /locus_tag="LSX49_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HBL7166504.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIIWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            29787..31160
                     /gene="proY"
                     /locus_tag="LSX49_000030"
     CDS             29787..31160
                     /gene="proY"
                     /locus_tag="LSX49_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HBL7166505.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            31316..33133
                     /gene="malZ"
                     /locus_tag="LSX49_000031"
     CDS             31316..33133
                     /gene="malZ"
                     /locus_tag="LSX49_000031"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308480.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HBL7166506.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVPMHKQRSQPQPGVTAWRAAIELSCGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARQEQFAIDVPDIGPQWAADQIFYQIFPDRFARNLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNTQQLGIRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNLQHVAGITEAAKETQPDAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDVARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     SALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWMN"
     gene            complement(33138..33719)
                     /gene="acpH"
                     /locus_tag="LSX49_000032"
     CDS             complement(33138..33719)
                     /gene="acpH"
                     /locus_tag="LSX49_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HBL7166507.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRNETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFT
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQSVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMEQASRKAL"
     gene            33812..34882
                     /gene="queA"
                     /locus_tag="LSX49_000033"
     CDS             33812..34882
                     /gene="queA"
                     /locus_tag="LSX49_000033"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBL7166508.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDQRSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            34937..36064
                     /gene="tgt"
                     /locus_tag="LSX49_000034"
     CDS             34937..36064
                     /gene="tgt"
                     /locus_tag="LSX49_000034"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBL7166509.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     gene            36087..36419
                     /gene="yajC"
                     /locus_tag="LSX49_000035"
     CDS             36087..36419
                     /gene="yajC"
                     /locus_tag="LSX49_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBL7166510.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            36447..38294
                     /gene="secD"
                     /locus_tag="LSX49_000036"
     CDS             36447..38294
                     /gene="secD"
                     /locus_tag="LSX49_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HBL7166511.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPSEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            38305..39276
                     /gene="secF"
                     /locus_tag="LSX49_000037"
     CDS             38305..39276
                     /gene="secF"
                     /locus_tag="LSX49_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HBL7166512.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            39406..39753
                     /locus_tag="LSX49_000038"
     CDS             39406..39753
                     /locus_tag="LSX49_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HBL7166513.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(39791..40675)
                     /gene="tsx"
                     /locus_tag="LSX49_000039"
     CDS             complement(39791..40675)
                     /gene="tsx"
                     /locus_tag="LSX49_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HBL7166514.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQLRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKVKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGYANNGIKTRTNNSIASSHILALNYDHWHYSVVARYWHNGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(40974..41513)
                     /locus_tag="LSX49_000040"
     CDS             complement(40974..41513)
                     /locus_tag="LSX49_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HBL7166515.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     KETVKITQQNKLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDTDGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     gene            41664..42113
                     /gene="nrdR"
                     /locus_tag="LSX49_000041"
     CDS             41664..42113
                     /gene="nrdR"
                     /locus_tag="LSX49_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HBL7166516.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     gene            42117..43220
                     /gene="ribD"
                     /locus_tag="LSX49_000042"
     CDS             42117..43220
                     /gene="ribD"
                     /locus_tag="LSX49_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBL7166517.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQGL
                     YPQQNLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGNDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            43309..43779
                     /gene="ribE"
                     /locus_tag="LSX49_000043"
     CDS             43309..43779
                     /gene="ribE"
                     /locus_tag="LSX49_000043"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBL7166518.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            43799..44218
                     /gene="nusB"
                     /locus_tag="LSX49_000044"
     CDS             43799..44218
                     /gene="nusB"
                     /locus_tag="LSX49_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBL7166519.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            44296..45273
                     /gene="thiL"
                     /locus_tag="LSX49_000045"
     CDS             44296..45273
                     /gene="thiL"
                     /locus_tag="LSX49_000045"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HBL7166520.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     gene            45251..45769
                     /gene="pgpA"
                     /locus_tag="LSX49_000046"
     CDS             45251..45769
                     /gene="pgpA"
                     /locus_tag="LSX49_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBL7166521.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVTAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAVILY
                     FIGHHWPLGILS"
     gene            complement(45823..46797)
                     /gene="yajO"
                     /locus_tag="LSX49_000047"
     CDS             complement(45823..46797)
                     /gene="yajO"
                     /locus_tag="LSX49_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HBL7166522.1"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKVGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGKNLYQESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     gene            complement(46852..48714)
                     /gene="dxs"
                     /locus_tag="LSX49_000048"
     CDS             complement(46852..48714)
                     /gene="dxs"
                     /locus_tag="LSX49_000048"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL7166523.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDATGMEAKIKAWLA"
     gene            complement(48739..49638)
                     /gene="ispA"
                     /locus_tag="LSX49_000049"
     CDS             complement(48739..49638)
                     /gene="ispA"
                     /locus_tag="LSX49_000049"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HBL7166524.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LTEQSFDTSALEALADYIIQRNK"
     gene            complement(49638..49880)
                     /gene="xseB"
                     /locus_tag="LSX49_000050"
     CDS             complement(49638..49880)
                     /gene="xseB"
                     /locus_tag="LSX49_000050"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBL7166525.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            50086..51534
                     /gene="thiI"
                     /locus_tag="LSX49_000051"
     CDS             50086..51534
                     /gene="thiI"
                     /locus_tag="LSX49_000051"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBL7166526.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSK
                     NWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            complement(51588..52178)
                     /gene="yajL"
                     /locus_tag="LSX49_000052"
     CDS             complement(51588..52178)
                     /gene="yajL"
                     /locus_tag="LSX49_000052"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HBL7166527.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(52141..53052)
                     /gene="panE"
                     /locus_tag="LSX49_000053"
     CDS             complement(52141..53052)
                     /gene="panE"
                     /locus_tag="LSX49_000053"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL7166528.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHDVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            53220..53711
                     /gene="yajQ"
                     /locus_tag="LSX49_000054"
     CDS             53220..53711
                     /gene="yajQ"
                     /locus_tag="LSX49_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HBL7166529.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            complement(53839..55203)
                     /locus_tag="LSX49_000055"
     CDS             complement(53839..55203)
                     /locus_tag="LSX49_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7166530.1"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHVLFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQMADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
                     YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEVEQA
                     IRQA"
     gene            complement(55352..56242)
                     /gene="cyoE"
                     /locus_tag="LSX49_000056"
     CDS             complement(55352..56242)
                     /gene="cyoE"
                     /locus_tag="LSX49_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HBL7166531.1"
                     /translation="MIFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            complement(56254..56583)
                     /locus_tag="LSX49_000057"
     CDS             complement(56254..56583)
                     /locus_tag="LSX49_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HBL7166532.1"
                     /translation="MSHSNASSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQILVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(56583..57197)
                     /locus_tag="LSX49_000058"
     CDS             complement(56583..57197)
                     /locus_tag="LSX49_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HBL7166533.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            complement(57187..59178)
                     /gene="cyoB"
                     /locus_tag="LSX49_000059"
     CDS             complement(57187..59178)
                     /gene="cyoB"
                     /locus_tag="LSX49_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HBL7166534.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQIYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            complement(59200..60147)
                     /gene="cyoA"
                     /locus_tag="LSX49_000060"
     CDS             complement(59200..60147)
                     /gene="cyoA"
                     /locus_tag="LSX49_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HBL7166535.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNSMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            complement(60607..62082)
                     /gene="ampG"
                     /locus_tag="LSX49_000061"
     CDS             complement(60607..62082)
                     /gene="ampG"
                     /locus_tag="LSX49_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HBL7166536.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTEYPAGYAFAMWTLAAGISLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            complement(62126..62704)
                     /locus_tag="LSX49_000062"
     CDS             complement(62126..62704)
                     /locus_tag="LSX49_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL7166537.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            63009..63326
                     /gene="bolA"
                     /locus_tag="LSX49_000063"
     CDS             63009..63326
                     /gene="bolA"
                     /locus_tag="LSX49_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HBL7166538.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            63670..64968
                     /gene="tig"
                     /locus_tag="LSX49_000064"
     CDS             63670..64968
                     /gene="tig"
                     /locus_tag="LSX49_000064"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBL7166539.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTEEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            65214..65837
                     /gene="clpP"
                     /locus_tag="LSX49_000065"
     CDS             65214..65837
                     /gene="clpP"
                     /locus_tag="LSX49_000065"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBL7166540.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            65963..67237
                     /gene="clpX"
                     /locus_tag="LSX49_000066"
     CDS             65963..67237
                     /gene="clpX"
                     /locus_tag="LSX49_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HBL7166541.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            67425..69779
                     /gene="lon"
                     /locus_tag="LSX49_000067"
     CDS             67425..69779
                     /gene="lon"
                     /locus_tag="LSX49_000067"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBL7166542.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            69988..70260
                     /gene="hupB"
                     /locus_tag="LSX49_000068"
     CDS             69988..70260
                     /gene="hupB"
                     /locus_tag="LSX49_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HBL7166543.1"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            70452..72323
                     /gene="ppiD"
                     /locus_tag="LSX49_000069"
     CDS             70452..72323
                     /gene="ppiD"
                     /locus_tag="LSX49_000069"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL7166544.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREAAIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            72474..72845
                     /locus_tag="LSX49_000070"
     CDS             72474..72845
                     /locus_tag="LSX49_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBL7166545.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAAPAAKPTTVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNMAVLTL"
     gene            72963..73361
                     /gene="fadM"
                     /locus_tag="LSX49_000071"
     CDS             72963..73361
                     /gene="fadM"
                     /locus_tag="LSX49_000071"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HBL7166546.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWHGLENSDSFHWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(73413..74108)
                     /gene="queC"
                     /locus_tag="LSX49_000072"
     CDS             complement(73413..74108)
                     /gene="queC"
                     /locus_tag="LSX49_000072"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HBL7166547.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLK"
     gene            complement(74173..75873)
                     /locus_tag="LSX49_000073"
     CDS             complement(74173..75873)
                     /locus_tag="LSX49_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HBL7166548.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTVL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSLRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LLAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQVMPDEE
                     NRFNALKAVFSQLMADATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            75973..76791
                     /gene="cof"
                     /locus_tag="LSX49_000074"
     CDS             75973..76791
                     /gene="cof"
                     /locus_tag="LSX49_000074"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HBL7166549.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            76944..77402
                     /gene="decR"
                     /locus_tag="LSX49_000075"
     CDS             76944..77402
                     /gene="decR"
                     /locus_tag="LSX49_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HBL7166550.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            77432..79204
                     /locus_tag="LSX49_000076"
     CDS             77432..79204
                     /locus_tag="LSX49_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HBL7166551.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFALLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRTMLAEAPVVIDGSDKVPEGRGE
                     LDVNIRQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLVQQSGWYRD
                     MYRYQQLEAALDDAPEIREEAVDA"
     gene            79197..80978
                     /locus_tag="LSX49_000077"
     CDS             79197..80978
                     /locus_tag="LSX49_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HBL7166552.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     SLQSGTIDVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSTLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTLLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            81159..81497
                     /gene="glnK"
                     /locus_tag="LSX49_000078"
     CDS             81159..81497
                     /gene="glnK"
                     /locus_tag="LSX49_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBL7166553.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            81527..82813
                     /gene="amtB"
                     /locus_tag="LSX49_000079"
     CDS             81527..82813
                     /gene="amtB"
                     /locus_tag="LSX49_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HBL7166554.1"
                     /translation="MKIATIKTGLTSLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNING
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(82862..83722)
                     /gene="tesB"
                     /locus_tag="LSX49_000080"
     CDS             complement(82862..83722)
                     /gene="tesB"
                     /locus_tag="LSX49_000080"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HBL7166555.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPDERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            83940..84512
                     /locus_tag="LSX49_000081"
     CDS             83940..84512
                     /locus_tag="LSX49_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HBL7166556.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            complement(84543..84854)
                     /locus_tag="LSX49_000082"
     CDS             complement(84543..84854)
                     /locus_tag="LSX49_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HBL7166557.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQLYRWN
                     Y"
     gene            85017..85113
                     /gene="ffs"
                     /locus_tag="LSX49_000083"
     ncRNA           85017..85113
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LSX49_000083"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            85233..85586
                     /locus_tag="LSX49_000084"
     CDS             85233..85586
                     /locus_tag="LSX49_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 family protein"
                     /protein_id="HBL7166558.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DIPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(85628..87178)
                     /gene="pdeB"
                     /locus_tag="LSX49_000085"
     CDS             complement(85628..87178)
                     /gene="pdeB"
                     /locus_tag="LSX49_000085"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HBL7166559.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDELAQGIITRLQKTPGEHIENNGIIYDILP
                     LPEMNISIITWASTKMLQKGWYRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(87342..87812)
                     /locus_tag="LSX49_000086"
     CDS             complement(87342..87812)
                     /locus_tag="LSX49_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaC family protein"
                     /protein_id="HBL7166560.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     gene            complement(87928..88479)
                     /gene="maa"
                     /locus_tag="LSX49_000087"
     CDS             complement(87928..88479)
                     /gene="maa"
                     /locus_tag="LSX49_000087"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HBL7166561.1"
                     /translation="MSTEKEKMIAGELYHSADEALSRDRLRARRLIHRYNHSLAEEHT
                     LRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     APGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
                     VVTKDVPDNVVVGGNPARIIKKL"
     gene            complement(88653..88871)
                     /gene="hha"
                     /locus_tag="LSX49_000088"
     CDS             complement(88653..88871)
                     /gene="hha"
                     /locus_tag="LSX49_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HBL7166562.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            complement(88897..89271)
                     /gene="tomB"
                     /locus_tag="LSX49_000089"
     CDS             complement(88897..89271)
                     /gene="tomB"
                     /locus_tag="LSX49_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HBL7166563.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
     gene            complement(89817..92966)
                     /locus_tag="LSX49_000090"
     CDS             complement(89817..92966)
                     /locus_tag="LSX49_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HBL7166564.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTNYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHNHTVDHH"
     gene            complement(92989..94182)
                     /gene="acrA"
                     /locus_tag="LSX49_000091"
     CDS             complement(92989..94182)
                     /gene="acrA"
                     /locus_tag="LSX49_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HBL7166565.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     AAYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            94324..94971
                     /gene="acrR"
                     /locus_tag="LSX49_000092"
     CDS             94324..94971
                     /gene="acrR"
                     /locus_tag="LSX49_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HBL7166566.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     gene            95099..98461
                     /gene="mscK"
                     /locus_tag="LSX49_000093"
     CDS             95099..98461
                     /gene="mscK"
                     /locus_tag="LSX49_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HBL7166567.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSALSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQVQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATQNGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VSKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQTLKDEFKSMKITVNWEKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLSGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNATEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(98500..98664)
                     /gene="rsmS"
                     /locus_tag="LSX49_000094"
     CDS             complement(98500..98664)
                     /gene="rsmS"
                     /locus_tag="LSX49_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HBL7166568.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPARTVLRALDIVKRDYEKK
                     LQSDETSQSE"
     gene            complement(98678..99205)
                     /gene="priC"
                     /locus_tag="LSX49_000095"
     CDS             complement(98678..99205)
                     /gene="priC"
                     /locus_tag="LSX49_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HBL7166569.1"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVAQFATLSARFDRHLFQTRAT
                     TLQACLDESGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREATAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRARLARATDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            99275..99652
                     /locus_tag="LSX49_000096"
     CDS             99275..99652
                     /locus_tag="LSX49_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HBL7166570.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGAKPRAILLILITFTISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            99805..100356
                     /gene="apt"
                     /locus_tag="LSX49_000097"
     CDS             99805..100356
                     /gene="apt"
                     /locus_tag="LSX49_000097"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBL7166571.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            100485..102416
                     /gene="dnaX"
                     /locus_tag="LSX49_000098"
     CDS             100485..102416
                     /gene="dnaX"
                     /locus_tag="LSX49_000098"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBL7166572.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQGVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPDPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSTFKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     misc_feature    101749..101813
                     /gene="dnaX"
                     /locus_tag="LSX49_000098"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            102469..102798
                     /locus_tag="LSX49_000099"
     CDS             102469..102798
                     /locus_tag="LSX49_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBL7166573.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            102798..103403
                     /gene="recR"
                     /locus_tag="LSX49_000100"
     CDS             102798..103403
                     /gene="recR"
                     /locus_tag="LSX49_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBL7166574.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            103513..105387
                     /gene="htpG"
                     /locus_tag="LSX49_000101"
     CDS             103513..105387
                     /gene="htpG"
                     /locus_tag="LSX49_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBL7166575.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETIISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYVTADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            105568..106212
                     /gene="adk"
                     /locus_tag="LSX49_000102"
     CDS             105568..106212
                     /gene="adk"
                     /locus_tag="LSX49_000102"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBL7166576.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            106344..107306
                     /gene="hemH"
                     /locus_tag="LSX49_000103"
     CDS             106344..107306
                     /gene="hemH"
                     /locus_tag="LSX49_000103"
                     /EC_number="4.99.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HBL7166577.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQYSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALEMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(107303..108262)
                     /gene="aes"
                     /locus_tag="LSX49_000104"
     CDS             complement(107303..108262)
                     /gene="aes"
                     /locus_tag="LSX49_000104"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HBL7166578.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGAIAEQRQYY
                     TLERRFWNADAPEMATRAYRVPTKYGQVKTRIFYPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVARRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSHLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            108414..109718
                     /gene="gsk"
                     /locus_tag="LSX49_000105"
     CDS             108414..109718
                     /gene="gsk"
                     /locus_tag="LSX49_000105"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HBL7166579.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            complement(109848..111524)
                     /locus_tag="LSX49_000106"
     CDS             complement(109848..111524)
                     /locus_tag="LSX49_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001582195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HBL7166580.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKSIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSVAALFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTR"
     gene            complement(111763..112983)
                     /gene="fsr"
                     /locus_tag="LSX49_000107"
     CDS             complement(111763..112983)
                     /gene="fsr"
                     /locus_tag="LSX49_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin MFS transporter"
                     /protein_id="HBL7166581.1"
                     /translation="MAMSEQTQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            113201..114853
                     /gene="ushA"
                     /locus_tag="LSX49_000108"
     CDS             113201..114853
                     /gene="ushA"
                     /locus_tag="LSX49_000108"
                     /EC_number="3.1.3.5"
                     /EC_number="3.6.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HBL7166582.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            complement(114891..115394)
                     /locus_tag="LSX49_000109"
     CDS             complement(114891..115394)
                     /locus_tag="LSX49_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166583.1"
                     /translation="MKFDHLVDVSFHNFVFNGKFDFVELGQTMAWLEQNFVEPDSKND
                     MGNGFYIWLFGNVEFHFENNKLYMIWCDYLSQIHLGKAIRFDKGILNNVAELNVTRVF
                     NMLVNEGADLQIRRQSPHTLLIHVNRSGVTLWFEADEEQPGDPQNYMLMAFGLTHRDY
                     DARFQYS"
     gene            complement(115391..116191)
                     /locus_tag="LSX49_000110"
     CDS             complement(115391..116191)
                     /locus_tag="LSX49_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166584.1"
                     /translation="MERITETLSIACADEIPDIALLRQTSREKVLHLHFASEAERYRE
                     EFGLVLKAQLDEFVVGMHSADPVIRIARLISLEEINRHQDFFEHCAKEYRKLATELIF
                     ALAEQLNVEMAENNPLVTFAPFKCNRKRKGKMGKWQYCFHGFHCTFENKKTEQNIEVP
                     LAYGFDFGDLDPYFFSGFIKSTPAWQPLPVAIYDDYHDGSRIIQQLLALGKLQKIPSP
                     IPQYTGVAAVDRSNVDIANFRSTLESRLHRCKLRWLLKHVKNSQRSER"
     gene            complement(116215..116694)
                     /gene="ybaK"
                     /locus_tag="LSX49_000111"
     CDS             complement(116215..116694)
                     /gene="ybaK"
                     /locus_tag="LSX49_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HBL7166585.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAASDLAKILDAKFADIARRD"
     gene            complement(116898..117692)
                     /locus_tag="LSX49_000112"
     CDS             complement(116898..117692)
                     /locus_tag="LSX49_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HBL7166586.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDISLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEDQLQNLQHIS
                     QEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            117825..118127
                     /locus_tag="LSX49_000113"
     CDS             117825..118127
                     /locus_tag="LSX49_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL7166587.1"
                     /translation="MAQKKNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIIN
                     AATSHRDLRSPPGNRYEELSGKLQEYSSIRVNKQYRLIFKWVNGKAEELFLDPHNY"
     gene            118163..118504
                     /locus_tag="LSX49_000114"
     CDS             118163..118504
                     /locus_tag="LSX49_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HBL7166588.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            complement(118562..121066)
                     /gene="copA"
                     /locus_tag="LSX49_000115"
     CDS             complement(118562..121066)
                     /gene="copA"
                     /locus_tag="LSX49_000115"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HBL7166589.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALI
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADIDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNDQQVDTKAIEADISA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            121328..122260
                     /gene="glsA"
                     /locus_tag="LSX49_000116"
     CDS             121328..122260
                     /gene="glsA"
                     /locus_tag="LSX49_000116"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL7166590.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTSDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKVGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENTEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLINTIELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEEGNSVRGQKMVASVAKQLGYNVFKG"
     gene            122263..123555
                     /locus_tag="LSX49_000117"
     CDS             122263..123555
                     /locus_tag="LSX49_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL7166591.1"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPEVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKPLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGALLLSLIVAMVMKRNKTV"
     gene            123680..124087
                     /gene="cueR"
                     /locus_tag="LSX49_000118"
     CDS             123680..124087
                     /gene="cueR"
                     /locus_tag="LSX49_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HBL7166592.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIEQHIEELQSMR
                     NQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(124088..124823)
                     /locus_tag="LSX49_000119"
                     /pseudo
     CDS             complement(124088..124823)
                     /locus_tag="LSX49_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601795.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(124917..125375)
                     /locus_tag="LSX49_000120"
     CDS             complement(124917..125375)
                     /locus_tag="LSX49_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBL7166593.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLLPLGWEWQGVMFAVLTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLIIRAVIA"
     gene            complement(125372..126289)
                     /locus_tag="LSX49_000121"
     CDS             complement(125372..126289)
                     /locus_tag="LSX49_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBL7166594.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLHIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            126435..127112
                     /gene="fetA"
                     /locus_tag="LSX49_000122"
     CDS             126435..127112
                     /gene="fetA"
                     /locus_tag="LSX49_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HBL7166595.1"
                     /translation="MQENSPLLQLQNVGYLAGDTKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNQQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            127099..127878
                     /gene="fetB"
                     /locus_tag="LSX49_000123"
     CDS             127099..127878
                     /gene="fetB"
                     /locus_tag="LSX49_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HBL7166596.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(128061..128915)
                     /gene="cnoX"
                     /locus_tag="LSX49_000124"
     CDS             complement(128061..128915)
                     /gene="cnoX"
                     /locus_tag="LSX49_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308582.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HBL7166597.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(128976..129785)
                     /gene="ybbO"
                     /locus_tag="LSX49_000125"
     CDS             complement(128976..129785)
                     /gene="ybbO"
                     /locus_tag="LSX49_000125"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HBL7166598.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHREGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVGKVRHAFISEKPKMRYPVTLVTRAVMVLKRLLPGRVMDKILQG"
     gene            complement(129775..130398)
                     /gene="tesA"
                     /locus_tag="LSX49_000126"
     CDS             complement(129775..130398)
                     /gene="tesA"
                     /locus_tag="LSX49_000126"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HBL7166599.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            130369..131055
                     /locus_tag="LSX49_000127"
     CDS             130369..131055
                     /locus_tag="LSX49_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7166600.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            131052..133466
                     /locus_tag="LSX49_000128"
     CDS             131052..133466
                     /locus_tag="LSX49_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7166601.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQIAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGSENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSIERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLVLSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVTVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WATLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVTPLKAF
                     LAEHQIVPESFYPVVRARLTAINDKPTEGNGDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKAGEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQSKVFDFPWEPDWRLWIVLPCSGALLLSLCGGWLGARLLKGKAL
                     FRQFVG"
     gene            133635..>133862
                     /gene="hcp"
                     /locus_tag="LSX49_000129"
     CDS             133635..>133862
                     /gene="hcp"
                     /locus_tag="LSX49_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HBL7166602.1"
                     /translation="MGDIIYLRITGEQQGDISAGCGTQVSVGNRYQQGHEDEIFVFSF
                     QGGVSNTGFGINHQAIQFCKILDKSSPLLMNC"
BASE COUNT        32631 a        33525 c        35443 g        32263 t
ORIGIN      
        1 tttcattaac gtattgaaat attgtgtttt tgttatttat ttctgtgtgt gtgttcacgt
       61 gctttatata tgtccgcaat cggacttagg ggaaagaata attgaaccat tcctctataa
      121 cgccgcataa tcgtaaacgc gaaacataat atgttttcta tgcattgata attgatggat
      181 caacttatta cgtccctgag gagggatgac aaatgcactc ctggaaaaag aaacttgtag
      241 tatcacaatt agcattggct tgcactctgg ctatcacctc tcaggctaat gcagcaaact
      301 atgatacctg ggggtatcat gacaacacca cgaccgattt agtttggccg tatgacactg
      361 acaatgatgg aattgccgat gctggcggca tggacccgat gggttcagac ggtaactacg
      421 taacttacaa tggttttgtt tactataaca atgccaatgg tgatttcgac accgtcttta
      481 aaggcgatac tgttaacggt accatttcta cttattactt gaatcatgat tacgctagcg
      541 gttctgttaa ccagttagat atcagcaatt cagtaattca tgggtcaatc acttctgaac
      601 tgccatttgg ttattacagc attactcctg cagaagttaa tgctaaaggt gaagttgtaa
      661 ctccacagac ctatagtggc tataatttct ataacggaat cactactgac cttgactaca
      721 attggtacga tggtgacgta ttcactctga acgtatccaa ttccaccatt gatgatgact
      781 atgaagctct ttacttcact gacacatatc ttgatggtga taaatctaag tcaaccaatg
      841 aaacgttcta taccgctctg ggtgttgcag taaatcttga tgttgaaagc aatatcaata
      901 ttactaacaa ctcccgtgta gctggtattg cgctgtctga aggcaataca agcaacacga
      961 cttatactag cgaatatcat cagtgggaca acaacattaa tgtgtctaac tccactgtaa
     1021 cttcagggtc acagactccg ctggaagaaa gcaatggctt cttcggtaaa tctgctgaac
     1081 caagtgatta cgctggtaat ggtggcgaaa atgacgtagc tctgtcattc tctgacaatg
     1141 ctggctcaaa ttattccatg aaaaacaatg taaactttga ccattcaacc ctgttgggtg
     1201 atgtcgagtt cacaagccac tggaataacg atggcgtatt cttctattca accggccatg
     1261 acagcaatgg tgacggtgtc cttgatacca acggtggttg ggtagatgat gctcagaacg
     1321 ttgatgaact gaacattact ctgaacaacg gtagtaagtg ggttggctca gcaaacatga
     1381 gtgctgaagt aattgctccg gcagatatgt atgatgttgc gccgaacagc ctgacccctg
     1441 gtgccactat cgaagctaac gattggggtc gtattattga caacaaggta ttccagagcg
     1501 gcgtatttaa cgtagcactg aacaatggtt cagaatggaa taccgttaat agttcagtaa
     1561 ttgatacatt agctgtaaat aatggctctc aggtaaatgt tactgattcc tctctggtct
     1621 cagataccat tggtttaacc aacggctcct cactgaatat tggtgaagat ggtttggttg
     1681 ctacagacca cctgactgtt gatagctaca gtaccgttaa tttaaccgaa tctactggct
     1741 ggaataacta ttctaacctg tatgccaata ccatcaccgt aactaacggt ggtgtactgg
     1801 atgtgaacgt tgatcagttt gatactgaag ctttccgtac tgacaaactg gaactgacta
     1861 gcggcaacat cgctgaccat aacggcaacg tagtttctgg tgtgttcgac atcaacagca
     1921 gcgattacgt tctgaacgcg gatttggtga acgaccgtac gtgggatact tccaagtcta
     1981 actacggtta cggtattgtt gctatgaact ctgatggtca cctgactatc aatggcaacg
     2041 gcgacgtaga caacggtact gaactggata acagttctgt agacaacgtt gttgctgcaa
     2101 ccggtaacta caaagttcgt atcgacaacg caactggcgc tggcgcaatc gctgattaca
     2161 aagataaaga aattatctac gtcaacgaca aaaacagcaa cgcgactttc tctgctgcta
     2221 acaaagctga cctgggtgca tacacctatc aggctgagca gcgtggtaac accgttgttc
     2281 tgcaacagat ggagctgacc gactacgcta acatggcgct gagcatcccg tctgcgaaca
     2341 ccaatatctg gaacctggaa caagacaccg ttggtactcg tctgaccaac tctcgtcatg
     2401 gtctggctga taacggcggc gcatgggtaa gctacttcgg tggtaacttc aacggcgaca
     2461 acggcaccat caactatgat caggatgtta acggcatcat ggtcggtgtt gataccaaaa
     2521 ttgacggtaa caacgctaag tggatcgtcg gtgcggctgc aggcttcgct aaaggtgata
     2581 tgaatgaccg ttctggtcag gtggatcaag acagccagac tgcctacatc tactcttctg
     2641 ctcacttcgc gaacaacgtc tttgttgacg gtagcttgag ctactctcac ttcaacaacg
     2701 acctgtctgc aaccatgagc aacggtactt acgttgacgg cagcaccaac tccgacgctt
     2761 ggggctttgg tttgaaagcc ggttacgact tcaaactggg tgatgcaggt tacgtaactc
     2821 cttacggcag cgtttctggt ctgttccagt ctggtgatga ttaccagctg agcaacaaca
     2881 tgaaagttga tggtcagtct tacgacagca tgcgttatga actgggtgta gatgcaggtt
     2941 ataccttcac ctacagcgaa gaccaggctc tgactccgta cttcaaactg gcttacgtct
     3001 acgacgactc taacaacgat aacgatgtga acggtgattc catcgataac ggtactgaag
     3061 ggtctgcggt acgtgttggt ctgggtactc agttcagctt caccaagaac ttcagcgcct
     3121 ataccgatgc taactacctc ggtggtggtg acgtagatca agactggtcc gcgaatgtgg
     3181 gtgttaaata tacctggtaa tattcttcac tccgaagaaa taggtaattt aatctaaata
     3241 atgcccgtca aggatttgac gggcattact gcaaaggacg cgcaaatgtt atctgtagtt
     3301 aaacctcttc aggaatttgg taagctcgat aaatgtttgt ccagatacgg tacgcgcttc
     3361 gagtttaata atgaaaagca agttatattt tccagtgatg tcaatagcga agatactttc
     3421 gttattttag aaggtgttat ctctctgcgt agagaagaaa acgtacttat cggtattaca
     3481 caggctcctt atattatggg gctggctgat ggtttaatga aaaacgatat accatacaaa
     3541 ttaatatcag aaggaaactg tacgggatat catttgccag ccaaacaaac cattactctt
     3601 attgaacaaa atcaactctg gcgagacgct ttttactggt tagcctggca aaatagaatt
     3661 ctggaattac gcgacgttca gctcattggg cataattcct acgaacaaat ccgcgcgacg
     3721 ttattatcaa tgattgactg gaatgaagaa ttgcgatcac gtattggcgt gatgaattat
     3781 atccatcaac gtacacgtat atcgcgttct gtcgttgcgg aagttctcgc tgctttgcgt
     3841 aaaggcggct atatcgaaat gaataaaggc aaactggtcg ctatcaaccg tttgccttca
     3901 gagtattaat caggatgcgg ggataaccaa cggtttattc ccgcttagct cggtcaccag
     3961 gtcattgatg ccatcgctca tatttttaaa gcgcgtcaac ggcgaacgag tgaccaccac
     4021 aaacgcacca atattcttct gcgggatcat cgccatatag gtaatgaaac cgccaccacc
     4081 acctgtcttc tgaataatcc ccggacgacc ctctttcggg gccatatata cccagcctaa
     4141 accaagcgca tccgctttgc cggggacatc catgccaatc acttttgtaa actgcgcgcg
     4201 ctgataaatc aacgtctgca tgcgatcagc ctggttactg cgttgataaa aatcagatga
     4261 caaatactgc tgcatccagc gcatcatatc gcctggcgtg gaatagacgc cgccgctgcc
     4321 aattgccgcc agcgtgttat tgcacggact ggcaccgcgc tcagcaacca ttaaacggcg
     4381 gcactgatcc ggtgaggggg tgtaggtggt gtctttcatc cccaacggac gggtaatctg
     4441 ctcttcaaac aactgggtat aaggcttgcc ggacgcattc gccagtgcat ctgccagcag
     4501 atcgaatgcg aggttggagt acgcggcctg gctgcccggc gcggctttta gtttggcagt
     4561 ggaaaggtat ttccagcgtt gctcgcgcgt tggccagaca aataccggac gatgtgccgc
     4621 gccaccgggc tgttcacggg gcagggcgct ggtatgggtt gccagattca ccagcgtaat
     4681 gggcgtccca ttgtaggtcg gtacgcgtgc gcctggcgga gcatatttac ttagcggatc
     4741 gtttaacttc acggtcccct ggtcgagcaa ttttaccagc atctcactgg tcattaactt
     4801 ggtgagggaa gcaatacgta tgacggaatc cagctgcggg cgaacgttat taccaggtcg
     4861 cgtttcgcca taactgcgaa agacgcgctg gttaccgtcg ataacaacca gcgccatccc
     4921 cgtggcaccg ctgccgtaaa aaatatgatc ggcataacga tcgacaatat cagaggcaaa
     4981 ctccggttca gtgatcggct gagccgcatg gacggaggtc aatgacgccg aatacagcac
     5041 ggcagaaaaa agcagactac gtttcaacgg tggtgtccat agattgaatg aaggtaactg
     5101 agcgtattta tactactcat tgatggattg caaagggcga attagtgcaa taatagtgtt
     5161 aaaaacgtaa cggcgcgtaa acacgatctt tttcctgctc accaatgcct gcatttgtga
     5221 tcctgcgcgt gttaatccgc ttatgtaaac aatctttggt ttgtgaaacc cgtcgaaaca
     5281 attcttatgg tcaggctggc gaactaagcg ccttgctatg ggtcacaatg ggcggtttca
     5341 tttggctgac gctttgtagc ggtcatgcgg ttaatacaca gcagttgtta aaacgataag
     5401 aagttagcag gagtgcatat gtttaagtct tttttcccaa agccgggaat gttttttctc
     5461 tcggcctttg tttgggcatt gattgccgtt atcttctggc aagtcggtgg gggtgattgg
     5521 gtggcgcgta tcaccggcgc ttccgggcag atcccgatta gcgccgcgcg tttctggtcg
     5581 ttggatttcc tgatttttta cgcttactac attgtttgcg taggactttt tgcattgttc
     5641 tggtttatct atagcccgca ccgttggcaa tactggtcaa tactcggtac tgcgctgatt
     5701 atcttcgtca cctggttttt ggtggaagtc ggggttgccg tcaacgcctg gtatgcgccg
     5761 ttctatgatc tgattcaaac ggcgctaagt tcgccgcata aagtcaccat cgaacaattt
     5821 taccgcgaag tgggcgtctt tctggggatt gcgctgatcg cggtggtgat cagtgtgctg
     5881 aacaacttct ttgtcagtca ctacgtgttc cgctggcgta cggcgatgaa cgaatattac
     5941 atggcgaact ggcaacaact gcgtcatatc gaaggggccg cgcagcgtgt gcaggaagac
     6001 accatgcgtt ttgcttcaac gctggagaat atgggcgtca gctttatcaa cgctatcatg
     6061 acgttgatcg ccttcctgcc ggtgctggta acgctctccg cacatgtgcc ggagctgccg
     6121 attgtcgggc acattccgta tggtctggtg attgccgcta tcgtctggtc gctgatgggg
     6181 accggattac tggcagtggt agggatcaaa ctgccggggc tggagtttaa aaaccagcgt
     6241 gtagaggctg cctaccgtaa agaactggtt tatggtgaag acgatgccac gcgcgtgacg
     6301 ccgcctacgg tacgcgagct ttttagcgcc gtacggaaaa actatttccg cctctatttt
     6361 cactatatgt atttcaatat cgcccgcatt ctctatttgc aggtcgataa cgttttcggt
     6421 ttgttcttgc tgtttccgtc aattgttgcc ggtacgatta cactcggcct gatgacgcag
     6481 attactaacg tttttggtca ggttcgcggt gctttccagt acctgattaa ctcatggacc
     6541 acactggttg agttgatgtc tatctacaaa cgtctgcgca gctttgaaca tgagctggat
     6601 ggtgacaaaa ttcaggaagt aacccatacc ttgagctaaa aaggagaagt aatgtcgcgc
     6661 gtcaatcctc tatcttcgct gtcattgttg gcggttctgg ttttagcggg gtgtagtagt
     6721 caggctccgc aaccgttgaa aaagggcgaa aaagcgatag atgtggcgag cgtcgtgcgg
     6781 cagaagatgc ctgcgagcgt gaaagaccgc gatgcctggg cgaaagatct cgccaccacc
     6841 tttgaaagtc aggggctggc accgacgctg gaaaacgtct gctcggtgct ggcggtggcg
     6901 cagcaggagt caaattatca ggcagatccg gccgttccgg gcttaagcaa gatcgcctgg
     6961 caagagattg accgtcgtgc tgaacggatg cacattcctg cttttctggt gcataccgcg
     7021 ctaaaaatca aatcgccaaa cggcaaaagc tatagcgaac ggttagattc ggtgcgtaca
     7081 gaaaagcaat tgagcgcgat ttttgacgat ctgatcagca tggtgccaat ggggcagacg
     7141 ctgtttggtt cgctcaatcc ggtgcgcacc ggtgggccga tgcaggtcag tattgctttt
     7201 gccgaacagc ataccaaagg gtatccgtgg aaaatggacg gtacagtccg tcaggaagtc
     7261 ttcagtcgcc gcggcgggtt gtggtttggt acttaccatt tactgaatta tcccgccagc
     7321 tatagcgcgc cgatataccg ttttgctgat tttaacgctg gctggtacgc cagccgtaat
     7381 gccgcgtttc agaacgcggt cagtaaggcc agcggcgtga agctggcact ggacggtgat
     7441 ttaattcgtt acgacagtaa agagcccggg aaaaccgaac tggcaacgcg caaactggcg
     7501 ggaaaactgg ggatgagtga cagcgaaatt cgccgtcagt tagagaaagg ggacagcttc
     7561 tcttttgagg agacggcgct gtacaagaaa gtttatcaac ttgccgaagc gaaaaccggt
     7621 aaatcactac cccgcgaaat gttgcctggc attcaactgg aaagcccgaa aatcacccgc
     7681 aatctgacta cggcctggtt tgcgaagcgc gtagacgaac ggcgggcgcg ttgtatgaaa
     7741 cagtgatcaa acaggaatgt cacgccagat aaggcgtttt aggccgcatc tggcaacgta
     7801 aatcttactg gcggcgatgt cgccagtgca gccatagcgc cactactgca aaaatgaggc
     7861 agcctactaa aaacgggatc agcccaaaaa tggtgccgac acctaaacca atttccaccc
     7921 gtgggcgacc tgtttcctgg acctgcatta aacgctcata gacgccgggc gcatgcacta
     7981 gcaggttcag caattgtgcc ccagcccaaa agcaaaacag cacaaacaac gcataggcaa
     8041 tattgccagg cgttgaagag gcattgcgat attttccgct aaacagcgat tttgacaggg
     8101 tgaaatcagc cataaaaacc tccggaagtc atctgcttct cttctggtgt gataccagcg
     8161 gcttatggca agtctgacag gtcatttaga ttgtcaatat cagaatcatg gtaaattgat
     8221 gttgggaata ttcccgaagc gtgaatcttc gttgcgagtc acaaaatagc aaccttaagt
     8281 taaatttatt aacaattgcg aaagtgttgt ctacaccaca gacagttgtt acagaatatg
     8341 aaaagatgtt gtttttcgtt aacggagctg ccatgaatct gcctgtaaaa atccgccgtg
     8401 actggcacta ctatgcgttc gccattggcc ttatattcat tcttaatggc gtggtggggt
     8461 tactgggatt tgaagcaaaa ggttggcaga cctatgccgt cggtctggtg acgtgggtga
     8521 ttagtttctg gctggcggga ttgattattc gtcgtcgcga tgaagaaact gaaaacgccc
     8581 aataagaata ttaccgggcg tttgaatatt acattgtggt tttcagtgcg ttatccgcag
     8641 cgtgacgctc cagcgccagc tcaatcaaac gcgtgatcag gtcggtgtaa cccagaccgc
     8701 tggcttgcca cagcttcgga tacatactga tgttggtgaa gccaggcagg gtgttgatct
     8761 cgttgatcac cacttcgttc tctggggtta aaaacacgtc tacacgcgcc atgcctgcgc
     8821 atcccaacgt ctgataagcc tgaacggcaa tcgcccggat cttatcgttg atttctggcg
     8881 caatggctgc cggaactacc actttcgcgc catcttcgtc aatgtacttg gtgtcgtagg
     8941 catagaaatc gctggtgagt acgatctcgc cacaggtgct tgcttgcggg ttattgttgc
     9001 caagaactgc gcattcgatt tcacgacctt tgatcccttg ctcaacgatc actttatgat
     9061 cgaactcgaa cgccagatcg acggcaattg tgtactgttc ttcactggtt actttgctga
     9121 caccaacaga agagccctga ttagccggtt ttacaaacag cggtaacccc agtttagact
     9181 ccacttcggc aaaactgatg ttgtgacgat tagcgcgcgt cagggtaata aatggcgcaa
     9241 tgttcagccc ggcatcgcgc agcagacgtt tggtgacatc tttatccata caggccgctg
     9301 aagccagaac atcagaacct acaaacggta aattggcgac ccgcagcatt ccctgcaagg
     9361 aaccatcttc gcccagcgta ccgtggacaa tcgggaaaat gacatccacc gtcggcaacg
     9421 gctgaccgtt ttgtgcgtcg ataagctgat gctcatgttt acctggcacc tgcgcaaggc
     9481 tggtcgccga aggacgcaac gcaatatggg caggatcgtc tgcatttagc agataattgc
     9541 tggcatcgct gacgtgccat tgcccttgtt tatcaatgcc cagcagcaca acatcgaagc
     9601 gacttttatc aatggcatcg acaatgtttt ttgccgattg cagagacact tcatgttccg
     9661 ctgatttacc accaaaaacg attcctaccc gcagtttttc catcttaaaa acctatcccg
     9721 tctaacacaa agtgcataca ttaccacgac aaaacggggg attcgcggcc ttctgacaga
     9781 atgttgcaat cttctgctga caaagcgagc aacgtactgg tgaagaaagt gcgttatctc
     9841 aaagatgtgt gcaagatcac aaaaatgatg aacgggaagc taatttattc ctggcttaaa
     9901 tgaccatgtg gtgagttttt ttctcttaat tataagataa cgaagagaat atatttcata
     9961 acttttattt ataataaagg ttgataatta aagacctata ttttatgtgg gtaattattt
    10021 aaataagaga aacgtttcgc tggtaatcaa acaaaaaata tttgcgcaaa gtatttcctt
    10081 tgtcataaaa ataatacttc cagacactat gaagttgtga aacataatgt taacttctcc
    10141 atactttgga taaggaaata cagacatgaa aaatctcatt gctgagttgt tatttaagct
    10201 tgcccaaaaa gaagaagagt cgaaagaact gtgtgcgcag gtagaagctt tggagattat
    10261 cgtcacggca atgcttcgca atatggcgca aaatgatcaa cagcggttga ttgatcaggt
    10321 agagggggcg ctgtacgagg taaagcccga tgccagcatt cctgacgacg atacggagct
    10381 gctgcgcgat tacgtaaaga agttattgag gcatcctcgt cagtaaaaag ttaatctttt
    10441 caacagctgt cataaagttg tcacggccga gacttatagt cgctttgttt ttatttttta
    10501 atgtatttgt acatggagaa aataaagtga aacaaagcac tattgcactg gcactcttac
    10561 cgttactgtt tacccctgtg acaaaagccc ggacaccaga aatgcctgtt ctggaaaacc
    10621 gggcagctca gggcgatatt actgcacccg gcggtgctcg ccgcttaacg ggtgatcaga
    10681 ccgctgctct gcgtgattct cttagcgata aacctgcaaa aaatattatt ttgctgattg
    10741 gcgatgggat gggggactcg gaaattactg ccgcacgcaa ttatgccgaa ggtgcgggcg
    10801 gcttttttaa aggtatcgat gccttaccgc ttaccgggca atacactcac tatgcgctga
    10861 ataaaaaaac cggcaaaccg gactacgtca ccgactcggc tgcatcagca accgcctggt
    10921 caactggtgt caaaacctat aacggcgcgc tgggcgtcga tattcacgaa aaagatcacc
    10981 caacgattct ggaaatggca aaagccgcag gtctggcgac cggtaacgtt tctaccgcag
    11041 agttgcagga tgccacgccc gctgcgctgg tggcgcatgt gacctcgcgc aaatgctacg
    11101 gtccaagtgc gaccagtgaa aaatgtccgg gtaacgctct ggaaaaaggc ggaaaaggat
    11161 cgattaccga acagctgctt aacgcccgtg ccgatgttac gcttggcggc ggtgcaaaaa
    11221 cctttgctga aacggcaacc gccggtgaat ggcagggaaa aacgctgcgt gaacaggcac
    11281 aggcgcgtgg ttatcagttg gtgagcgatg ctgcctcact gaattcggtg acggaagcga
    11341 atcagcaaaa acccctatta ggactgtttg ctgacggcaa tatgccagtg cgctggcaag
    11401 gaccgaaagc aacgtaccac ggtaatatag ataagcccgc agtcacctgt acgcctaatc
    11461 cgcaacgtaa tgacagtgta ccgaccctgg cgcagatgac cgacaaagcc attgaattgt
    11521 tgagtaaaaa tgagaaaggc tttttcctgc aagttgaagg tgcgtcaatc gataaacagg
    11581 atcacgctgc gaatccttgt gggcaaattg gcgagacggt cgatctcgat gaagccgtac
    11641 aacgggcgct ggaattcgct aaaaaggatg gtaacacgtt ggtcatagtc accgctgatc
    11701 acgcccatgc cagccagata gttgcgccag ataccaaagc tccgggcctc acccaggcgc
    11761 taaataccaa agatggcgca gtgatggtga tgagttacgg gaactccgaa gaggattcac
    11821 aagaacatac cggcagtcag ttgcgtattg cggcgtatgg cccgcatgcc gccaatgttg
    11881 ttggactgac cgaccagacc gatctcttct acaccatgaa agccgccctg gggctgaaat
    11941 aaaaccgcgc ccggcagtga attttcgctg ccgggtggtt tttttgctgt tagcaaccag
    12001 acttaatgac agatcacggg cgcatacgct catggttaaa acatgaagag ggatggtgcg
    12061 atgaaaatta cattactggt taccttgctt ttcggtctgg tttttttaac caccgtcggc
    12121 gctgccgaga gaaccttaac cccacaacaa cagcgtatga cctcttgtaa tcagcaggcg
    12181 acggcgcagg cgttgaaagg ggatgctcgt aagacctaca tgagtgattg cctgaagaac
    12241 agcaaatctg cgcctggtga aaaaagtttg acgccacagc agcaaaagat gcgcgaatgt
    12301 aataatcaag caacacaaca atctctgaaa ggggatgatc gtaataagtt tatgagtgcc
    12361 tgcctcaaga aagccgcctg atacctgata gtgctaacgg gtgagctacg aaaatggctc
    12421 acccgaaatt tcatacttct gcctttagtc ccgtctctat aatttgggaa aattgtttct
    12481 gaatgttccc aaaaataatg aatgatgaaa actttttcaa aaaagcggcg gcgcatgggg
    12541 aggaacctcc tttaactcct caaaacgaac atcagcggtc cgggctgcgc ttcgcccgtc
    12601 gcgtcagact accccgcgcg gttggtctgg ctggcatgtt cttaccgatt gcttcaacgc
    12661 tggtttcgca cccgccgccg ggctggtggt ggctggtgtt ggtcggctgg gcgttcgtct
    12721 ggccgcattt agcctggcag atagcgagca gggccgtcga tccgcttagc cgggaaattt
    12781 acaacttaaa aaccgatgca gtattagcgg gaatgtgggt aggcgtaatg ggcgtaaacg
    12841 tgctgccttc caccgcgatg ttgatgatta tgtgtctgaa tttgatgggg gcaggcggcc
    12901 cccgtctgtt tgttgcgggt ctggtgttga tggtggtttc ctgccttgtc accctcgaac
    12961 tgacgggcat caccgtgtcg ttcaatagcg caccgctgga atggtggctc tcccttccca
    13021 ttattgtcat ttatcctctg ctgtttggct gggtcagcta ccagacggcg actaaactgg
    13081 cggaacataa acgcaggttg caggtcatga gtacccgcga cggtatgacg ggcgtgtata
    13141 acagacgtca ttgggaaact atgttacgca atgaatttga taactgtcgg cggcataatc
    13201 gcgatgcaac gttactgatt atcgatatcg accatttcaa gagcatcaac gatacctggg
    13261 gccatgatgt gggtgatgaa gcgattgtgg cgcttacccg acagttacaa attaccctgc
    13321 gcggtagcga tgtgattggt cggtttggcg gcgatgagtt tgcagtaatc atgtccggta
    13381 cgccagctga gagcgccatc accgccatgt tacgggtgca tgaagggcta aacacgttac
    13441 gcttgccgaa tacgccacag gtaactttac ggattagtgt gggggttgcg ccgctgaatc
    13501 cacaaatgag tcactatcgc gagtggttga aatcggcaga tttggcgctc tacaaagcaa
    13561 agaaagccgg acgtaaccgc accgaagtgg cggcctgacg tccggcaaaa gccatcagga
    13621 tttgctgagt ttttctgatt tttccataca cttcgtcatc gcttcgatca ctgcggcacg
    13681 gaagcctttc tcttccagta cgcgtaccgc ctcaatggtg gtgcctcccg gtgagcagac
    13741 catatctttc agtgttcccg gatgttctcc cgtttccagc accatttttg cggagcccat
    13801 taccgcctga gcggcaaatt tatacgcctg ggcgcgtggc atcccgccca gcacggcggc
    13861 gtcggccatc gcttcgataa acataaagac gtaggctggc gaagaaccgc tcacaccgac
    13921 caccgggtgg atcatcggct cagcaatcac ttccgcttcg ccaaagcagc ggaaaatatt
    13981 cagcacatca gcggtatctt ctggggttac cagcgcgttt ggcgttacgg aggtcatccc
    14041 ggcattaacc agcgcgggag tgttcggcat ggcgcggata attttccggt catggcccag
    14101 cgcgcgggca agctggtcga gcgtgatacc tgcagcaata gaaacgacca gagagtcttt
    14161 attcaggctg gaggtgattt cgctaagcac tttaatcatg atgcctggtt taacggcggc
    14221 aaaaatgatg tcggcgattt gcgctacttc ttgcgccgat tctgcggcgt tgatgccgaa
    14281 ctgttcatgc agggcggtga ctttatccgg ggagggggta tatacccaga tttgccctgg
    14341 aagcacctga ccgctggcaa tcagaccgcc gagaatggct tttcccatat tgccgcagcc
    14401 aataaaaccg attttctttt ccattgcctc actcctgccg tgaaattcat tgttttgata
    14461 atcgctggca gaagcataaa cagaactatg ccggaaggca aaagcgcgac acaatagagg
    14521 attacccaac aaaggatgac tttatgacaa tttgggtgga tgccgacgcg tgtcccaatg
    14581 taattaaaga gattttgtat cgcgcggcgg aacgtatgca gatgccgctg gtactggtag
    14641 caaaccagag tttacgcgtg ccgccatcac gatttattcg tacgctgcgc gtcgcggcag
    14701 gtttcgacgt tgccgataac gaaattgttc ggcagtgtga agcgggcgat ttggtgatca
    14761 ccgcagatat acctttggct gctgaagcca ttgagaaagg cgcggcggcg cttaatccgc
    14821 gcggcgaacg ttatacgcca gcgaccattc gtgagcgcct gacgatgcgc gattttatgg
    14881 ataccttacg tgccagtggg atccagaccg gaggaccaga tagtctttca caacgtgacc
    14941 gccaggcttt tgctgcggag ctggagaagt ggtggctgga agtgcaacgt agtcgtggct
    15001 aaatgtaatt tattatttac acttcattct tgaatattta ttggtatagt aagggatgta
    15061 ttgagatttt cactttaagt ggaatttttt ctttacaatc gaaattgtac tagtttgatg
    15121 gtatgatcgc cattctcatg acaccggctt tcgccgcatt gcgacctatt ggggaaaacc
    15181 cacgatgaca caacctcttt ttctgatcgg gcctcggggc tgtggtaaaa caacggtcgg
    15241 aatggccctt gccgattcgc ttaaccgtcg gtttgtcgat accgaccagt ggttgcaatc
    15301 acagctcaat atgacggtcg cggagatcgt cgaaagggaa gagtgggcgg gattccgcgc
    15361 cagagaaacg gcggcactgg aagcggtaac tgcgccatcc accgttatcg ccacgggcgg
    15421 cggcattatt ctgacggaat ttaatcgtca cttcatgcaa aataacggga tcgtggttta
    15481 tttgtgtgcg ccagtatcag tcctggttaa ccgactgcaa gctgcaccgg aagaagattt
    15541 acggccaacc ttaacgggaa aaccactgag cgaagaagtt caggaagtgc tggaagaacg
    15601 cgatgcgcta tatcgcgaag ttgcgcatat tatcatcgac gcaacaaacg aacccagcca
    15661 ggtgatttct gaaattcgca gcgctctggc acagacgatc aattgttgat tttcgagcgc
    15721 ctatacttaa cgttcatccc gtgaaataag gaagaacgat gccaacgaaa ccgccttatc
    15781 ctcgtgaagc atatatagtg acgattgaaa aaggaaagcc aggacagacg gtaacctggt
    15841 accaactcag agccgatcat cctaaaccag actcgttgat cagtgaacat ccgaccgctc
    15901 aggaagcgat ggatgcgaaa aaacgctatg aggaccctga caaagagtga ccgcatcaga
    15961 ccgctcggaa gggattctga gtgccgccac aagggatctg cgtcacattt ttcacaattc
    16021 atgtttttca aataattaga atattaaaca ataacaatcc attactggaa tcatttggaa
    16081 tctttacatt atgcagtgca ggtctgctgc tacgcttttt gtcatttgta gcacaagtaa
    16141 gtgtcagcag tggtgcttaa cacttgcccg gtaattaacg acgaaataaa agtaaggtgg
    16201 aagaacaatg agtgcgtcgt tggcgatcct gactatcggc attgtaccta tgcaggaagt
    16261 tttgccgctc ctgacagaat acattgacga agataatatt tcccatcata gcctgctggg
    16321 gaagttaagc agcgaagaag tgatggcgga gtacgcgcca gaagcaggcg aagacacaat
    16381 tctcacatta ttaaatgaca accatctggc ccatgtttcg cgtcgcaaag ttgagcgaga
    16441 cctgcaaggt gtggttgaag tgctcgataa tcagggttac gacgtcatta tattaatgag
    16501 tacagcaaac attagtagta tgaccgcgcg taatacgatc tttcttgagc cgtcgcggat
    16561 attgccaccg ctggtttcct ctattgttga agatcatcag gtgggggtta tcgtaccggt
    16621 tgaggagttg ctgaccgttc aggcgcaaaa atggcaaatt ttgcagaaac cgccagtatt
    16681 ttcattgggt aaccccattc atgattcgga acaaaaaatc attgatgccg ggaaagaatt
    16741 actggcaaaa ggtgcagatg tcatcatgct ggattgtttg ggatttaacc agcgtcatcg
    16801 cgatttactg caaaaacagc tcgatgttcc tgtcttgctc tctaacgtat tgattgcacg
    16861 gctggctgcg gaattactga tgtaattttg cgtgacagcc agcgcctctg gcccctatag
    16921 tgaagtagat gttcaactac cagacagggc cagtttatgc ttcaaagtaa tgagtacttt
    16981 tccggcaaag tgaaatcgat cggcttttcc agcagcagca ctggtcgcgc cagcgtgggt
    17041 gttatggttg aaggtgaata caccttcagc accgctgagc ctgaagagat gacggtaatc
    17101 agtggcgcgc tgaatgtgtt actgcctgac gcgaccgact ggcaagtgta tgaagccggt
    17161 tcggtgttta atgttcccgg tcacagcgag tttcatctgc aagttgccga acccacctct
    17221 tatctgtgcc gctatctgta attcctcgcc ttccccttga acgggagggc atttttctga
    17281 aatgtcctct ctttaaccca taataatatt tcctttgctg ggattttttc gatttccgat
    17341 atattcataa ttcatcaagg ttgatatcaa tatcagcgaa gatctccaga tattgttgcg
    17401 gaactggcga cgataaaaga taaatcagat gatgaatggt ggcgtgcatt gctgcaaagt
    17461 cgcaatgatc atttgcgcca aacggcattg cacaacgcac ataccccggt gttgttgtta
    17521 acgacattga ctgagcctca ggagcggtcg ctggctatta ataattcaca gctggctgcc
    17581 gatgtgaaaa cggcgtggtt aaaagaggat ccatcattac tcttatttgt cgaacaaccc
    17641 gatctttcgc tgttacgtga tttagtgaaa accggggcaa cgcgaaaaat tcgcagtgaa
    17701 gcgcgtcacc ggcttgagga aaaacaatga cacaacgccc ctggagcaag ttacagcata
    17761 aaacgcataa tattgctgcg ctaagaatta ttgcccgctg tagctaacga ttatattcct
    17821 ggtgtggctt cgtacgccgg ataagacgcg gcaggcgtcg catccggcat taaaggtaaa
    17881 tcagcaatta acgttgtgct tcgccaccta atccttcaat caggttttga attaacgctg
    17941 ccagttcacc agtcatcagg atgaaatcgg catcaaagcg ctgggcgaaa tcttcacggt
    18001 cgatatcttc gttttgatcg cgcagctcgt cgcagaactt cagacgcttg agcgaaccat
    18061 cgtcgcacat cacaaactga atgcgctgct gccagtcgag cgccagttta gtcaccactt
    18121 ttccggcttc aatgtggttg gtgatctctt cgctggtcag atcttgtttc ttcgcgcgga
    18181 tcacgccgcc atcttccagc aacgatttca gctcggcttc atcaagcagc tggaagccct
    18241 gtgccgcgct gccggaacgt acccattcgg tcagcgtcag ttcaatcggg ttttccatgc
    18301 tcaatggtac aaccggtaac gaccccaggc ttttacgcag cagtgccagc gtatcttccg
    18361 cttttttggc gctggcgcag tccaccataa tcaaaccgtt aaccgtatcg atccacatca
    18421 ttgtctggct aaaacggctg aaagcacgcg gcagcagaga gtgcagcact tcgtctttca
    18481 gcgaatcttt ttcggttttc ttcagcttac gcacctgttc cgcttccagt ttggcgattt
    18541 tcgcttccag cgcctgttta atcaccgggg acgggaggat tttttcttct ttgcgcgcac
    18601 agataacaat ttgaccattg gcaacgtgcg ttaacgcatc gctgtgcgat cccatcggag
    18661 gtacccagcc catcttcgcc atgtcctggc tgccgcatgg ggtaaatgcc atcgaggcta
    18721 gctgtttttc catctcttct gcacgcagcg aaatctcgcg gctaagacgg taaaccatta
    18781 aatttttgaa ccacagcatg ataatttcca cggccttgtc gttaaattta gcgggcatga
    18841 taacgaattg tcggcggcct tgcattgcca atccggttgt ccgtctctac gctattgata
    18901 ttgaaaaaaa taaggagagt accgtgcgta taggtatcga tttaggcggc accaaaactg
    18961 aagtgattgc attgggcgat gcaggggagc agttgtaccg ccatcgtctg cccacgccgc
    19021 gtgatgatta ccggcagact attgaaacga tcgccacgtt ggttgatatg gcggagcagg
    19081 caacagggca gcgcggaacg gtaggtatgg gcattccagg ttcgatttcg ccctacaccg
    19141 gcgtggtgaa gaatgccaat tcaacctggc tcaacggtca gccattcgat aaagacttaa
    19201 gcgcgcggtt gcagcgggaa gtgcggctgg caaatgacgc caactgtctg gcggtttcag
    19261 aagcggtaga tggcgcggca gcgggagcgc agacggtttt tgccgtgatt atcggcacgg
    19321 gatgcggcgc gggcgtggca ttcaatgggc gggcgcatat cggcggcaat ggcacggcag
    19381 gcgagtgggg acacaatccg ctaccgtgga tggacgaaga cgaactgcgt tatcgcgagg
    19441 aagtcccttg ttattgcggt aaacaaggtt gtattgaaac ctttatttca ggcacgggat
    19501 tcgcgacgga ttatcgtcgt ttgagcggac atgcgctgaa aggcagtgaa attatccgcc
    19561 tggttgaaga aagcgatccg gtagcggaac tggcattgcg tcgctacgag ctgcggctgg
    19621 caaaatcgct ggcacatgtc gtgaatattc tcgatccgga tgtgattgtc ctgggcggcg
    19681 gaatgagcaa tgtagaccgt ttatatcaaa cggttccgca gttgattaaa caatttgtct
    19741 tcggcggaga atgtgaaacg ccggtacaca aggcgaaaca tggtgattcg agcggcgtac
    19801 gcggcgctgc atggttatgg ccacaagagt aaaaaaccca ggcaattggc gtatcatgcc
    19861 tgatgcgacg cttgccgcgt cttatcaggc ctacaaagtg agccgtccgg taggccggat
    19921 aaggcgctcg cgccgcatcc ggcaacaaat aacgcgcaca gtggcggcaa ccccccggtg
    19981 ctccgatgcc tgatgcgaca ctggcgtgtc ttatcaggcc tacaaaatga acagtcccgt
    20041 aggccggata aggcgttcac gccgcatccg gcaataagca acgtgcaccg tgactgcaat
    20101 ctaccccagt ggtttcgcca gcaccggact atccgccgct tgctggcgct tatagcgacc
    20161 atacagcagc aacgacgaca tcgcagcaaa cgaaagcagg gcggcgggca gcgccacgta
    20221 attatatgcc agccccagcg tcagcatcat accaccgcaa tatgcgccga cggcgctacc
    20281 gaggttaaac gctatttgcc cacctgcggc acctaataac tctccgcctt tggcattttg
    20341 cagtaataat atttgtagag gtgctgaaag ggcaaataat cccgcgcaac aaataaaagc
    20401 aaaaataagc gacgttgttt tcataccgcc gaagaaaaag agcatcagca gtgccagtac
    20461 aatgataaag tcagtcactg ctgcaatgcg cagtggtgaa taacgtcctg aaatcctgcc
    20521 acttagcata ttccccagca ccatccctag cccaactaac atcataataa aggtcatcgc
    20581 cgtttccgaa aaaccggaaa taaacatcat gtatggcttt acgtagctga accaggcaaa
    20641 cacacctgcg ttgccaaaca tcgtagcagc gaaaattaac cacggggcag ggctgcgtaa
    20701 aaagtgaaat tgttcgcgta gttttccttt cgcctcgtcg cgaatatccg gcacccaaaa
    20761 atagaccgat gccatcaccg caatattaaa aatagcgatc aacaaaaagg tgtaacgcca
    20821 gctaaattcc tgacttaaat acgttcccag tggaatgccc agcaaattgg cgactgtcat
    20881 cccggaaacc atccctgcca cggcggcggt gactttgccg ggtttgataa tttttgataa
    20941 cacgatcgcg ccgacgccaa aaaatgcacc atgcgggaag ccggaaacca gccgaccaat
    21001 ggcgagcatc aggtaagacg aagagagcgt gaacatggcg ttgccaatga cgcacaacgc
    21061 caccagaaac aacaagatat gtttgagtga gtagcgactg gaaaaaagcg cgatgattgg
    21121 cgcaccgacc accaccccca gcgcataata cgagatcata tgcccggcgg caggaatcga
    21181 aattcctacg ttatgcgcca gctccgtgag cacgcccata atgccaaatt cggccatccc
    21241 caaaccaaac gtgcccagag ccaaagataa aataactttt ttcataccac catcacaacc
    21301 accagaacgg ctaccaatca ccgtagccaa taaagtgata gcttgcagga taacgaccag
    21361 tcgggccaag agataattcg cccctctgta ttcattatcc tgctgaatag ttatttcact
    21421 gcaaacgcac tttccagttt gctgtagccc agtccattga tcttcttcac tttgatctgc
    21481 accggaatac gctctttcat cgcttcaacg tggctaatca ccccgatggt tttgccactg
    21541 gcattcaggg catccaacgc atcaagggcg gtatccagcg tttcgctatc cagcgtgcca
    21601 aaaccttcat caaggaacag cgagtcaata cgcgttttat ggctgaccag atctgaaagc
    21661 gccagtgcca gcgccagact gacgaggaaa ctttcgccgc cggaaagggt acgggtatcg
    21721 cgtaccgcat cagcctgcca ggtatcaaca acctcaactt ccagcgcctc gctggctttg
    21781 cgctgtaaca gatagcgccc gtgcagccgg gtaagttgct gattagcgag atggactaaa
    21841 ttatccagcg tcagcccttg ggcaaatttg cggaatttat cgccctcttt ggaacctatt
    21901 agcgaattca gatatcccca gtcctcaacc tgctgcgtca tttgagcaat ttgctgcatt
    21961 aaggtttgtt gttgctgacg gttatctgca tcctgcttca gctgctggcg aatctcgcct
    22021 tgactcgtgg tgttttcacg caacttttgg tgagtttgcg ctaactcttg ctgaatctgc
    22081 tccaccgtca cagtgagaga caacccgcca ggtcggtgtt gctgatgctg tgtcagcgtt
    22141 tctgctgtct gagtgaccag cgtttgcgcc tgacggcgct ggttttccag attctgcttg
    22201 agctgttcca gctgcgttag tgtttgttca tccattagcg ccgcaaggaa cgcctgctga
    22261 tcgtcaaaga cgctcgcctg tagcgcggtg tcaaactgcg cctgggcttt ttgcagactt
    22321 tgcgccgcca gaacatcctg ttgctgtaac gtctgctgct ggctgtgtaa tgcgagacat
    22381 tgttcatgaa cctgccgcca gttttccagc gccacagttt cttcgctgtg cgggagttca
    22441 tcactttgcg gcaacgtttc cagaatcggc gtcagctgct gcatacggtt ttgcagcgcg
    22501 gttaattcgt tctggcgttg ctgccagctc tgcgcttctt gctgacgcgt cgccaaccag
    22561 ctctcttctt catcttcctg tggcaatgtc agtgcataac ccgccaatgc cgttaagagc
    22621 tgctgctggc gttgttcaat ttgctgttga tactggataa tttgctgatt atgcgcggca
    22681 atctgccctt gtaattcatg ccgttggctg agtaaccgca gctggcgttc gtgctcatct
    22741 tgtgcatcca gccacggttg aatatcgtcc tgtggctgca gggtgatatt gaggctggcc
    22801 gtgacggctt gccattgttg agtaagtgct tgctcatctt gtcggaggct ttgcgcttcg
    22861 ttttcatcgc gctgaagttg ctttgttaag gcgtccagtt gcccacgtag cgtcgcacct
    22921 tcttcgccga gctttttcac ttctttttcc agcgttaata gccgggcctg attaacgccc
    22981 ggttccagcg cctgatacgc ctcgaccgcc gggtggctgg tggaaccaca aagtgggcaa
    23041 ggctgacccg cctgtaactg tgcgcgctgg gcttccagcg ttttaatgcg cgcttcctgc
    23101 tcgcaaatgg ttttcacatc ggcaagttgt tgcatctttt ctttataacg atggcgcatt
    23161 ttgttaagtg cggcattacg ttgcgtctgc tccagagtga cgttctggat agcgacctgt
    23221 aactgcgcca gacgtttttg ttggggaaca atctgcccat gcagtgcgac caggcgctga
    23281 cgcagtgggc gttgctcagc atgttgcgcc tgggcgctag caacttcatc ggcggttaac
    23341 gtcaacgtga tcgccgcaag cgcattaagt ttttgctcag catgggttaa ctgttgctgc
    23401 cattgccgca gatgctcgcg atcgctggtt tgttgggaga actgcgcacg ccaacccgcc
    23461 agttcgttgt tccactgacg gaagcggtcg tgttcctgta accaggcatt caggctttgt
    23521 tgctgctgct gtaattctgc tgactgcttc gccgcgtggt ggcgaatgct cgcacgaagc
    23581 gccattgtgc tctgtaagcg agtatttact tcttcaatct gctggcgagt atgcgccagc
    23641 gccgtgctgt gttctgcgat gcgttcccag tgcggacgaa gatttcgtgc cggttgtgcc
    23701 agactgagcg ccgccagttg aggttgcgct tgttcttctt cggctaatgc ctgttgcaag
    23761 gcctgttgac ggcggctggc ttcttgctgc aattcgtcca gacgcgttaa ccagtttagc
    23821 gattgttgtt cttgctgctg cgcggtaatt aactgttttt cttcgtcagt aagtacctgc
    23881 aaactcgctg tcagcgattg cacttgttcc ggcgtgagca acgcgacgcc gctggcctgc
    23941 gcttgcagct tctccagctc tgtgcgggcc gatttgtgct gctcaaaaac catcgccgag
    24001 atttgcccgt agatttcagt gccggttaac tcctcgagca attctgcgcg ttctttgggt
    24061 ttggcattca ggaaggcagc aaattgcccc tgcgaaagca gcatcgaacg ggtgaagcgc
    24121 ccgtaatcca gtccggttaa cgtcgccgtc agttccagct tatctttcac tttgtcggcg
    24181 agaattttgc cgtctgcaca gcgcgccagc tctacgcgtg gcacctgcaa attaccgtcc
    24241 ggctggttac gcgcccgatt ctggctccag aacgcgcgat acgcttcatc tttgacttca
    24301 aactccactt ccgccagaca ttcggcggta tcgcgggtca tgagatcatt ttgcgattgt
    24361 gaaacgttag agaggcgcgg agtttcgtga tacagcgcca gacaaatggc gtccagcagg
    24421 gtggttttcc ccgcaccggt tgggccggta atagcaaaca gcccgttgct ggcgaacggc
    24481 tcgcgggtga aatcaatctt ccattcgcct tttaatgagt tcaggttttt caggcgcagg
    24541 ctgagaattt tcatgcttcg tgttctccgg cgaggctatg caacgtcgtg gcgaaaagat
    24601 gctgcagacg ttgctgctgt gattcatcca gttcttccag tgccagacgg cgattgaaca
    24661 cctcttcgac gctgagttcg ctgagggttt cacgctgttg gctggctaac acacgctcgc
    24721 gctgttcacg actccggcgt accagcaata cttcgacagg caatgattcg gttaatgcct
    24781 ggattttgcg ctgaatatca tgcagatact catcagtagt gatttcgata tccagccaga
    24841 caggcggctc ctgtgataca tcgcgccact gttccagctg tgcggtaatc gacgccagat
    24901 cgcctttcag caccgccatg ggttgcgtta ccggtacgtt caggttttcc acgctctcta
    24961 atttgccgtt tgaaaatgtc accagatgga catatttact cttaccgcat tcatcaaaac
    25021 tcagtggaat gggggagccg caatagcgaa catgttccat gccgccaata agctgcgcgc
    25081 ggtgaatatg cccgagcgcg atgtagtcgg ctggtggaaa gttttgtgcc ggaaacgcgt
    25141 ccagcgtgcc aatataaatg tcacgcacgg cgtcactttt actggcaccc acggtcgtta
    25201 aatgtccagt ggcgatgatg ggcagaggct gatcgccgcg cagtttgcag gcatcggcat
    25261 aatgttgttg ataataatca gtaatagccg ccagcaaatg ctgctgtttt tcaataccgt
    25321 taagccccgc ctggctggta ataatgtcac gcgggcgtaa aaaaggtatg ggacacagca
    25381 ctgcgcctgg cgtcccgtcg cgacggggca atatttgcgg cgcatgtccg gcgctggcga
    25441 ccacggtagt attgaggaac gccatgatat cgcgcgattc attcagcgtg gcgaccgagt
    25501 catggtttcc tgccagtacc accagatgac agccagtttg ctgtaaattg acaacaaaac
    25561 ggttgtataa cgtgcgggcg taactgggcg gcgagccggt atcgaaaaca tcaccggcaa
    25621 caataatcgc atccaccaga tgggcttgtg ctgtctccag cagccagtca agaaaagcct
    25681 gatgttcagc ttcgcggctt ttactgtaga agttctggcc gagatgccag tctgaggtgt
    25741 gaaggatgcg cataacggtt ccctggcgaa aaagcatggg cgcgattata cccaaacaga
    25801 tgtgccattt gcttttttct gtgccacgga aatcaataac ctgaagatat gtgcgacgag
    25861 cttttcataa atctgtcata aatctgacgc ataatgacgt cgcattaatg atcgcaacct
    25921 atttattaca acagggcaaa tcatggcgag acgtattctg gtcgtagaag atgaagctcc
    25981 aattcgcgaa atggtctgct tcgtgctcga acaaaatggc tttcagccgg tcgaagcgga
    26041 agattatgac agtgctgtga atcaactgaa tgaaccctgg ccggatttaa ttctccttga
    26101 ctggatgtta cctggcggct ccggtatcca gttcatcaaa cacctcaagc gcgagtcgat
    26161 gacccgggat attccagtgg tgatgttgac cgccagaggg gaagaagaag atcgcgtgcg
    26221 cggccttgaa accggtgcgg atgactatat caccaagccg ttttctccga aggagctggt
    26281 ggcgcgaatt aaagcggtaa tgcgccgtat atcgccgatg gcggtggaag aggtgattga
    26341 gatgcagggg ctaagtctcg atccgacatc tcaccgggtg atggcgggcg aagaaccgct
    26401 ggagatgggg ccaactgaat ttaaactgct gcactttttt atgacgcatc ccgagcgcgt
    26461 gtacagtcgc gagcaactgt taaatcacgt atggggaacc aacgtgtatg tggaagatcg
    26521 tacggtcgat gtccacattc gtcgcctgcg taaagcactg gagcccggcg ggcatgaccg
    26581 catggtgcag accgtgcgcg gtacagggta tcgtttttca acccgctttt aaggccttgc
    26641 tcatcggacg tagagcaggg cttatgattt cttaactgga gtatcttacg tgctggaacg
    26701 gctgtcgtgg aaaaggctgg tgctggagct gctattttgc tgcctcccgg ctttcatcct
    26761 gggtgcattt ttgggttacc tgccctggtt tttgctggca tcggtaacag gactgcttat
    26821 ctggcatttc tggaatttat tgcgcctttc atggtggctg tgggtggatc gtagtatgac
    26881 cccgccaccg gggcgtggta gctgggaacc gctactatac ggcttacacc agatgcagct
    26941 gcgaaataaa aaacgccgcc gtgaactggg caatctgatt aaacgctttc gtagcggcgc
    27001 ggagtcgctg cccgacgcgg tggtgctgac cacggaagag ggcggtattt tctggtgcaa
    27061 cggtctggcg caacagattc ttggcttgcg ctggccggaa gataacgggc agaacatcct
    27121 taacttgctg cgttacccgg agtttacgca atatctgaaa acgcgtgatt tctctcgccc
    27181 gctcaatctg gtgctcaata ccgggcggca tctggagatt cgcgtcatgc cttataccca
    27241 caaacagttg ctgatggtgg cgcgagatgt cacgcaaatg catcaactgg aaggggcgcg
    27301 gcgtaacttt tttgccaacg tgagccatga gttacgtacg ccattgaccg tgttacaggg
    27361 ttacctggag atgatggatg agcaaccgct ggaaggcgcg gtacgtgaaa aagcgttgca
    27421 caccatgcgt gagcagaccc agcggatgga agggttggtg aagcaattgc tgacgctgtc
    27481 gaaaatagaa gccgcaccga cgcatttgct caatgaaaag gttgatgtgc cgatgatgct
    27541 gcgcgtcgtt gagcgcgagg ctcagactct gagtcagaaa aaacagacat ttacctttga
    27601 gatagataac ggcctcaagg tgtcaggcaa cgaagatcag ctacgtagtg cgatttcgaa
    27661 cctggtctat aacgccgtga atcatacgcc ggaaggcacg catatcaccg tacgctggca
    27721 gcgagtgccg cacggtgccg aatttagtgt tgaagataac ggaccgggca ttgcaccgga
    27781 gcatattccg cgcctgaccg agcgttttta tcgcgttgat aaagcgcgtt cccggcaaac
    27841 cggtggtagc ggattagggt tagcgatcgt gaaacatgcg gtgaatcatc acgaaagtcg
    27901 cctgaatatt gagagtacag taggaaaagg tacacgtttc agttttatta tcccggaacg
    27961 tttaattgcc aaaaacagcg attaattcgc ctttgtcatc ttttattgcc ataagccagc
    28021 cgatgctggc ttattttctt tgcagtcgaa atacgggcgt tagattttac aatggttggt
    28081 gattttttgt tcgcatgatt agccatgtct ttttcattga aatagtgttt tatactggtt
    28141 ggtgatttct tatcgctata tacctctggt ttttagatcc cttcttgctt taaaacgtta
    28201 taagcgttta aattgcgctt caggtgctgt catactgact gcatttacgc ggtaaatcga
    28261 aaaactattc ttcgccgcgc ctggttggga gtatttcccg ctaaaattgt ttaaatatac
    28321 cgctgtatca tccccaggga ttggcacaaa aatttaacgt tacaacacca catccacagg
    28381 cagtatgatt tatgacccat caattaagat cgcgcgatat catcgctctg ggctttatga
    28441 catttgcgtt gttcgtcggc gcaggtaaca ttattttccc tccaatggtc ggcttgcagg
    28501 caggcgaaca cgtctggact gcggcattcg gcttcctcat tactgccgtt ggcctaccgg
    28561 tattaacggt agtggcgctg gcaaaagttg gcggcggtgt tgacagtctc agcacgccaa
    28621 ttggtaaagt cgctggcgta ctgctggcaa cagtttgtta cctggcggtg gggccgcttt
    28681 tcgctacgcc gcgtacagct accgtttctt ttgaagtggg cattgcgccg ctgacgggtg
    28741 attccgcgct gccgctgttt atttacagcc tggtctattt cgctatcgtt attctggttt
    28801 cgctctatcc gggcaagctg ctggataccg tgggcaactt ccttgcgccg ctgaaaatta
    28861 tcgcgctggt catcctgtct gttgccgcaa ttatctggcc ggcgggttct atcagcacgg
    28921 cgactgaggc ttatcaaaac gctgcgtttt ctaacggctt cgtcaacggc tatctgacca
    28981 tggatacgct gggcgcaatg gtgtttggta tcgttattgt taacgcggcg cgttctcgtg
    29041 gcgttaccga agcgcgtctg ctgacccgtt ataccgtctg ggctggcctg atggcgggtg
    29101 ttggtctgac tctgctgtac ctggcgctgt tccgtctggg ttcagacagc gcgtcgctgg
    29161 tcgatcagtc tgcaaacggt gcggcgatcc tgcatgctta cgttcagcat acctttggcg
    29221 gcggcggtag cttcctgctg gcggcgttaa tcttcatcgc ctgcctggtc acggcggttg
    29281 gcctgacctg tgcttgtgca gaattcttcg cccagtacgt accgctctct tatcgtacgc
    29341 tggtgtttat cctcggcggc ttctcgatgg tggtgtctaa cctcggcttg agccagctga
    29401 ttcagatctc tgtaccggtg ctgaccgcca tttatccgcc gtgtatcgca ctggttgtat
    29461 taagttttac acgctcatgg tggcataatt cgtcccgcgt gattgctccg ccgatgttta
    29521 tcagcctgct ttttggtatt ctcgacggga tcaaggcatc tgcattcagc gatatcttac
    29581 cgtcctgggc gcagcgttta ccgctggccg aacaaggtct ggcgtggtta atgccaacag
    29641 tggtgatggt ggttctggcc attatctggg atcgcgcggc aggtcgtcag gtgacctcca
    29701 gcgctcacta aatcactgaa catttgtttt aaccacgggg ctgcgatgcc ccgtggtttt
    29761 ttattgtgtt gatgggttag gaattgatgg aaagtaagaa caagctaaag cgtgggctaa
    29821 gtacccgaca catacgcttt atggcactgg gttcagcaat tggcaccggg ctgttttacg
    29881 gttcggcaga tgccatcaaa atggccggtc caagcgtgtt gttggcctat attatcggtg
    29941 gtatcgcggc gtatatcatt atgcgtgcgc tgggggaaat gtcggtacat aacccggcag
    30001 ccagctcttt ctcgcgttat gcgcaggaaa acctcggccc gctggcaggt tacattaccg
    30061 gctggaccta ctgctttgaa atccttattg tcgccatcgc cgatgtgacc gcttttggta
    30121 tctatatggg tgtctggttc ccgacggtgc cgcactggat ttgggtactg agtgtggtgc
    30181 tgatcatttg cgccgtaaac ctgatgagcg tgaaggtatt cggtgagctg gagttctggt
    30241 tctcgttctt taaagtcgcc actatcatca tcatgattgt cgccggtttc ggcatcatca
    30301 tctgggggat tggcaacggc gggcaaccga ccggtattca taacctgtgg agcaacggcg
    30361 gcttcttcag taacggctgg cttggtatgg tgatgtcgtt gcaaatggtg atgtttgctt
    30421 acggtgggat cgaaattatc gggattaccg ccggtgaagc gaaagatcct gagaaatcga
    30481 ttccgcgtgc gattaactcc gtgccgatgc gtattctggt gttctacgtc ggtacgctgt
    30541 tcgtcattat gtctatctac ccgtggaatc aggttggcac tgccggtagc ccgtttgtgc
    30601 tgacgttcca gcatatgggc attacctttg ccgccagcat tcttaacttt gttgtgctga
    30661 ccgcttcgct gtcggcaatt aacagtgacg tatttggtgt aggccgtatg ctccacggta
    30721 tggcagagca gggcagcgcg ccaaaaattt tcagcaaaac ctcgcgtcgc ggtattccgt
    30781 gggttacggt gctggtgatg actaccgcgc tgctgtttgc ggtgtatctg aactacatca
    30841 tgccggaaaa cgtcttcctg gtgatcgctt cgctggcaac cttcgccacg gtgtgggtgt
    30901 ggattatgat cctgctgtcg caaatcgcct tccgtcgccg tttgccgcca gaagaagtta
    30961 aggcgctgaa atttaaagtg ccgggtgggg tagcaacgac catcggcggt ttgattttcc
    31021 tgctctttat tatcgggttg attggttatc accctgatac gcgtatctcg ctgtatgttg
    31081 gtttcgcgtg gattgttgtg ctgttgattg gctggatgtt taagcgccgc cacgatcgtc
    31141 agctggctga aaaccagtaa tccttgcgtt ctgtaagccg gttcaggagg aaatcctgat
    31201 ccggctattc cgaaagttat ccgcccccgt cctcctcccc caaatatcct tcagatgatg
    31261 agtgatcctg cattaggcta tggcaaggtg atcagatttt catcacaggg gaattatgat
    31321 gttaaatgca tggcatctgc cggtgccccc atttgttaaa caaagcaaag atcaactgct
    31381 cattacactg tggctgacgg gcgaagaccc accgcagcgc attatgctgc gtacagaaca
    31441 cgataacgaa gaaatgtcag taccgatgca taagcagcgc agtcagccgc agcctggcgt
    31501 caccgcatgg cgggcggcga tcgagctctc ctgcggacaa cctcggcggc gttatagttt
    31561 caaattgctg tggcacgatc gccagcgttg gtttacaccg caaggcttca gccgaatgcc
    31621 gccggcacga caggagcagt ttgccatcga tgtaccggat atcggcccac aatgggctgc
    31681 ggatcagatt ttttatcaga tcttccctga tcgtttcgcc cgtaatcttc ctcgtgaagc
    31741 tgaacaggat catgtctatt accatcacgc agccggacaa gagatcatat tgcgtgactg
    31801 ggatgaaccg gtcacggcgc aggctggcgg atcaacgttc tatggcggcg atctggacgg
    31861 gataagtgaa aaactgccgt atctgaaaaa acttggcgtg acggcgctgt atctcaatcc
    31921 ggtgtttaaa gctcccagcg tgcataaata cgataccgag gattatcgcc atgtcgatcc
    31981 gcagtttggc ggtgatgggg cgttgctgcg tttgcgacac aatacgcagc agctgggaat
    32041 acgactggtg ctggacggcg tgtttaacca cagtggcgat tcccatgcct ggtttgacag
    32101 gcacaatcgt ggcacggggg gagcttgtca caaccccgaa tcaccctggc gtgactggta
    32161 ctcgtttagt gatgatggca cggcgctcga ctggctgggc tatgccagct tgccgaagct
    32221 ggattatcag tcggaaagtc tggtgaatga aatttatcgc ggggaagaca gtattgtccg
    32281 ccactggctg aaagcgccgt ggaatatgga tggctggcgg ctggatgtgg tgcatatgct
    32341 gggggaagcg ggtggggcgc gcaataattt gcagcacgtt gccgggatca ccgaagcggc
    32401 gaaagaaacc cagccggatg cgtatattgt cggcgaacat tttggcgatg cacggcaatg
    32461 gttacaggcc gatgtggaag atgccgccat gaactatcgc ggcttcacat tcccgttgtg
    32521 gggatttctt gccaacaccg atatctctta cgatccgcag caaattgacg cccaaacctg
    32581 tatggcctgg atggataatt accgcgcagg gctttctcat caacaacaat tacgtatgtt
    32641 taatcagctc gacagccacg atactgcgcg atttaaaacg ctgctcggtc gggatgttgc
    32701 gcgcctgccc ctggcggtgg tctggctgtt cacctggcct ggtgtaccgt gcatttatta
    32761 cggtgatgaa gtgggactgg atggcaaaaa cgatccgttt tgccgtaagc cgttcccctg
    32821 gcaggtggaa aagcaggatt cggcgttatt cgcgctgtac cagcgaatga ttgcgctgcg
    32881 taagaaaagt caggcgttgc gtcgtggcgg ctgtcaggtg ctgtatgcgg aagataacgt
    32941 ggtggtattt gtccgcgtgc tgaatcagca gcgtgtactg gtggcaatca accgtggcga
    33001 agcctgtgaa gtggtgctac ccgcgtcgcc gttgcttaat gtcgcgcaat ggcaacgcaa
    33061 agaaggtcac gggcaactga cggacgggat tctggctttg cctgccattt cggctacggt
    33121 gtggatgaat taacgtctta taacgccttg cgtgacgcct gctccatcat ccgcggataa
    33181 aactgccaga agcgggtttc gagagcatcg taatgggcgt ctaaatcgta ccaggagtca
    33241 cgcagggcat ccagacgtgg gcgacggctt gccatgccgt ttaacacgct ctggatgaaa
    33301 tccatatcgc gatagcgcac caaccactgc tctgaccata agtagttgtt cagattgata
    33361 aagcgtggcg gtgagtctgg aagaatagtc atcacttgct cccgggcata acaggtaaat
    33421 tcctgtagcg gaaaatcggg cgacagctgc gaccagtggc gggacagaaa gtgatcccac
    33481 atcacatcca gcgtaatagg cgcgacacgg cgcgtttcat tacgaaacca ctcccgcgct
    33541 tcgcggactt ctggcagatt gtcggttaat acgtcgattc gccgatgcat atgaatgcca
    33601 gccacgacgt cgggcggaaa actttcttca ggatttccgc gtacgaaatc agccagtaaa
    33661 ttgccggaaa gcgagctttc cgcgagatgg gctaaatgca ggtgagctaa aaaattcatc
    33721 gattatattc tatccaaagg ggggtaaagg ttgcagggag agcgccccgg cactagacta
    33781 cccgcctctt attttagtct gagtcagtgt catgcgcgtt accgatttct cttttgaatt
    33841 gcccgaatcc ctgattgccc actatcccat gcctgaacgc agtagctgtc gtttactgtc
    33901 gctggacggg ccgacgggcg cgctgacgca cggtactttc accgatttac tcgataagct
    33961 caaccccggc gatcttctgg tttttaataa tacccgcgtg atcccggcgc gtctgtttgg
    34021 gcgtaaagcc agcggcggca agattgaagt gctggttgag cggatgctcg acgacaaacg
    34081 cattcttgcg catattcgcg cctcgaaagc gccaaaacct ggcgcagaac tgctgctggg
    34141 cgatgacgaa agtattaacg caacaatgac cgcgcgccac ggcgcactgt ttgaagtcga
    34201 atttaatgat caacgttcgg tgctggatat tctcaacagc atcggccata tgccgctgcc
    34261 gccgtacatc gaccgtccgg acgaagatgc agaccgcgaa ctttatcaaa cggtttatag
    34321 cgaaaaaccc ggcgcggtag cagcaccgac cgccggactg cactttgacg aacctttgct
    34381 ggaaaaatta cgcgccaaag gcgtggagat ggcgtttgtg acgttgcacg ttggtgcggg
    34441 caccttccag ccggtgcgcg tcgacaccat tgaagatcac atcatgcact cggaatacgc
    34501 tgaagtgccg caggatgtgg tagacgcggt actggcggcg aaagcgcgcg gtaaccgggt
    34561 gattgcggtt ggcaccacct cagtacgttc gctggaaagt gcggctcagg cagcgaaaaa
    34621 cgatctcatt gaaccgttct ttgacgatac ccaaatcttt atctatccgg gcttccagta
    34681 caaagtggtc gatgcgctgg tgacgaactt ccaccttccg gaatcgacgc tgattatgct
    34741 ggtttcggca tttgctggtt atcaacacac catgaatgcc tataaagcgg cggtagaaga
    34801 gaaatatcgc ttttttagtt acggtgatgc gatgtttatc acgtacaatc cgcaggcaat
    34861 taatgagcgc gttggggagt aattccgcgg cgctggttta aacgttggac tgtttttctg
    34921 acgtagtgga gaaaaaatga aatttgaact ggacaccacc gacggtcgcg cacgccgtgg
    34981 ccgcctggtc tttgatcgtg gcgtagtgga aacgccttgt tttatgcctg ttggcactta
    35041 cggcaccgta aaagggatga cgccggaaga agttgaagcc actggcgcgc aaattatcct
    35101 cggcaacacc ttccacctgt ggctgcgccc gggccaggaa atcatgaaac tgcacggcga
    35161 tctgcacgat tttatgcagt ggaaaggacc aatccttacc gactccggcg gcttccaggt
    35221 tttcagcctt ggtgatattc gtaaaatcac cgaacagggt gttcacttcc gtaacccgat
    35281 caacggcgac ccgattttcc tcgacccgga aaagtcgatg gagattcagt acgatcttgg
    35341 ttcggatatc gtcatgatct ttgatgagtg tacgccgtat cctgctgact gggattatgc
    35401 aaaacgctcc atggagatgt ctctgcgttg ggcgaagcgt agccgtgagc gttttgacag
    35461 tctcggaaac aaaaatgcgc tgtttggtat cattcagggc agtgtttacg aagatttacg
    35521 tgatatttct gttaaaggtc tggtagatat cggttttgat ggctacgctg tcggcggtct
    35581 ggctgtgggt gagccgaaag cagatatgca ccgcattctg gagcatgtat gcccgcaaat
    35641 tccggcagac aaaccgcgtt acctgatggg cgttggtaaa ccagaagacc tggttgaggg
    35701 cgtacgtcgc ggtatcgata tgtttgactg cgtaatgcca acccgcaacg cccgaaatgg
    35761 tcatttgttc gtgaccgatg gcgtggtgaa aatccgcaat gcgaagtata agagcgatac
    35821 tggcccactc gatcctgagt gtgattgcta cacctgtcgc aattattcac gcgcttactt
    35881 gcatcatctc gaccgttgca acgaaatatt aggcgcgcga ctcaacacca ttcataacct
    35941 tcgttactac cagcgtttga tggcgggttt acgcaaggct attgaagagg gtaaattaga
    36001 gagcttcgta actgattttt accagcgtca ggggcgagaa gtaccacctt tgaacgttga
    36061 ttaatattaa taatgaggga aatttaatga gcttttttat ttctgatgcg gtagcggcaa
    36121 cgggtgcacc ggcgcaaggt agcccgatgt ctttgatttt gatgctggtg gtattcggtc
    36181 tgattttcta tttcatgatc ctgcgtccac agcagaagcg caccaaagaa cacaaaaagc
    36241 tgatggactc catcgctaaa ggtgatgaag tgctgacgaa cggtggcctg gtcggtcgcg
    36301 taaccaaagt agcggaaaac ggctacattg ctatcgcact gaatgacacc actgaagtag
    36361 ttattaaacg tgacttcgta gctgccgttc tgccgaaagg caccatgaag gcgctgtaat
    36421 taaaattttt ccctaaggga attgccgtgt taaaccgtta tcctttgtgg aagtacgtca
    36481 tgctgatcgt ggtgattgtc atcggtctgc tgtatgcgct tcccaacctg tttggtgagg
    36541 atccggctgt tcagatcact ggtgcgcgcg gagtcgccgc cagtgagcaa acgctgatcc
    36601 aggtccagaa aacgttacaa gaagaaaaaa taactgctaa gtctgtggca ctggaagagg
    36661 gcgctattct tgcgcgcttc gactccactg acacccagct gcgcgctcgt gaagcattaa
    36721 tgggcgttat gggtgacaaa tacgtcgtgg cgcttaatct tgccccggca acgccgcgct
    36781 ggctggcagc tattcatgct gagccgatga agctcggcct tgacctgcgt ggcggcgttc
    36841 acttcctgat ggaagtggat atggacaccg cgcttggcaa actccaggaa caaaatatcg
    36901 atagcctgcg cagcgacctg cgtgaaaagg gcatcccgta taccaccgtt cgtaaagaaa
    36961 acaactacgg cctgagcatc actttccgcg atgctaaagc tcgtgatgaa gccattgcgt
    37021 atctgagcaa gcgccatccg gacctggtga ttagcagcca gggcagcaac cagctgcgtg
    37081 cggtaatgag cgatgctcgt ctgagtgaag cgcgtgaata tgcggtgcag cagaacatca
    37141 atatcctgcg taaccgtgta aaccaacttg gcgtggcgga gccggtggtt cagcgtcagg
    37201 gtgctgaccg tatcgttgtt gaactgccag gtattcagga cactgcgcgt gcgaaagaga
    37261 ttctgggtgc gacggcaacg ctggaattcc gtctggtaaa caccaacgtt gatcaggccg
    37321 ctgcggcatc cggtcgcgta ccgggcgact ctgaagtgaa acagacccgc gaaggtcagc
    37381 cggttgtgct gtacaaacgc gtaattctga ccggtgacca tatcaccgac tccacttcca
    37441 gccaggacga atacaaccag ccgcaggtta acatctctct cgatagcgcg ggtggtaaca
    37501 tcatgtctaa cttcaccaag gacaacatcg gcaaaccgat ggcaaccctg tttgtggagt
    37561 acaaagacag cggtaagaaa gatgcaaacg gtcgtgcggt tctggtgaaa caggaagagg
    37621 tgattaatat cgccaacatc cagtctcgtc tgggtaacag cttccgtatt actggcatca
    37681 ataacccaag cgaagcgcgt cagctttcac tgctgctgcg tgccggtgcg ttgatcgcgc
    37741 cgattcagat tgttgaagaa cgtaccattg gcccaaccct gggtatgcag aacattgagc
    37801 aggggctgga ggcttgcctt gccggtctgc tggtttctat tctgttcatg atcatcttct
    37861 ataagaagtt tggtctgatt gcgaccagtg ctctgattgc caacttgatc ttgattgtcg
    37921 gtattatgtc gctgttgcca ggcgcaacgc tgagtatgcc aggtatcgcg ggtatcgtct
    37981 taacccttgc ggtagcggtc gatgcgaacg tactgatcaa cgaacgtatt aaagaagagt
    38041 tgagcaacgg acgtactgtt caacaggcaa ttgatgaagg ttatcgtggc gcattcagtt
    38101 ccatcttcga tgcgaacatc accacgctga ttaaagtcat catcctgtac gcagtgggta
    38161 ccggggcaat taaagggttc gcgattacta ccggtatcgg tgtggcgacg tcgatgttta
    38221 ccgcgattgt cggtacgcgt gccatcgtaa acctgctata tggcggcaag cgcgtcaaga
    38281 agctgtcaat ctgaggagtg cgatgtggca caggaatata ctgttgaaca actaaaccac
    38341 ggccgtaaag tctatgactt tatgcgctgg gactactggg ctttcggcat ctctggtctg
    38401 ctgttaatcg ccgctatcgt tattatgggc gtgcgcggct ttaactgggg gctggatttc
    38461 accggtggta cggttattga aattacgctc gaaaaaccgg ctgaaattga cgtaatgcgt
    38521 gatgcattgc aaaaagccgg ttttgaagag ccgatgctgc aaaactttgg tagcagccac
    38581 gacatcatgg tccgtatgcc gcctgctgaa ggcgaaaccg gtggtcaggt gctgggcagc
    38641 caggttctga aggtgattaa cgaatccacc aatcagaatg cggcagtgaa gcgtattgag
    38701 ttcgtcggtc cgagcgtggg ggcagacctt gcgcaaaccg gtgcgatggc gttgatggcg
    38761 gcgctgctgt ctatcctcgt gtacgttggt ttccgctttg agtggcgact ggcggcaggg
    38821 gttgttattg cgctggcgca cgacgttatc attacgctgg gtattttgtc gttattccat
    38881 atcgagattg acctgaccat tgtggcatcg ttgatgtcgg ttatcggtta ctcgcttaac
    38941 gacagtatcg tggtatcgga ccgtattcgt gaaaacttcc gcaagatccg tcgcggtacg
    39001 ccttacgaaa tctttaacgt gtccttgacc cagacgctgc accgtacctt gatcacatcc
    39061 ggtactacct tgatggttat cctgatgctg tacctcttcg gtggtccggt actggaaggc
    39121 ttctcgctga ccatgcttat cggtgtttcc atcggtactg catcttccat ctatgtggca
    39181 tctgcgctgg ctctgaaact gggtatgaag cgcgaacaca tgttgcagca gaaagtggaa
    39241 aaagaagggg cggatcagcc gtcaattctg ccttaatcaa gtttcagctg atgttgaaaa
    39301 tcccggtcag aagatcggga ttttttttga tgtaaggtga ttgcgaaaat ccccgcatct
    39361 tgggaaactg cgcgtaaccc tacatttcat ccaggtaact ttttcatggc tatcatccca
    39421 aaaaactatg cgcggttaga aagcggctat cgcgaaaaag cattaaaaat ctatccgtgg
    39481 gtctgcggtc gctgttcccg cgagtttgtt tattccaacc tgcgtgaact taccgttcac
    39541 cacattgatc acgaccatac taataacccg gaagatggca gtaactggga attactttgt
    39601 ctctattgcc acgatcatga gcattcgaaa tacaccgaag cggatcagta tggtacgacc
    39661 gttatcgcag gggaagatgc gcagaaagat gtcggtgaag cgaagtacaa cccattcgct
    39721 gatttgaaag cgatgatgaa caagaagaag tgataaaaaa tgccggatat gaaatccggc
    39781 attctcacaa ttagaagttg taacctacta ccagataacc accccagccg gtagagcgaa
    39841 cgttgaagtt gccgttgccg aagttcagtt ctgcatcgtc attccactga ccaccgttat
    39901 gccagtaacg ggcaacgaca gagtagtgcc agtgatcgta attcagcgcc agaatatggc
    39961 tggacgcaat agagttattg gtacgtgttt taataccgtt gttcgcataa ccgctgtcat
    40021 cgcccaggtc ggaaccccag tcgaagttgg tgaagccgat gtagctcagc tggccgcccc
    40081 acagatcggt aatcggcaca aagtacttca ctttgaaacg gtaaccgtcc cactcgtttt
    40141 cgttcgctgc gccgtagttc tgccactggt atttcgcata gacgttcatg gacaggctca
    40201 tcggcagacc agtatcgatg tcggtaccca gacccatgta ccaggtgctc tggcggccat
    40261 ctttattacg acccatgtcg taaatgtagt tgttcgcgaa gtaccactct ttgaacggac
    40321 cgaagctaag gtcagtattg gtcagcttgt caatggagaa acgcggttcg atttccataa
    40381 acagcggaga accgtggttc cagatacctt ttgcatcgga gttaccgccg aagaataccg
    40441 gcgcatccgc ataaccatag aagtcgaacc agtctttttt agcgaatgct tcgtactcaa
    40501 ggtaggtatc gttgcggagc tgcggtccga aacgggtgtg atagcttccg acaacgttaa
    40561 cgctctggtg ccaccagtcg gaaagatact gcggtttgtc gttttcagct gcgttgacag
    40621 taaaagacga agagagcgcc agtaccgcac cggctgccag taatgttttt ttcatatgta
    40681 tgccactgtt tgaaaatccc ttgcgggagt gaaaaaggcg caaattgcgt ttctaaatat
    40741 ttcgtataca gaggagccta ttataaaaat cattgctcac aaaaatatgt ttcgtttcac
    40801 agttctatca tttacgtaat cgattgcgtt cacgtttaca cacattcggg cggggattgt
    40861 actgactttc acccttgttg caaactttta ctatcaatcc aggtgatgta agcggagtaa
    40921 caaaatgacg gagaaagatg ttgcgggacg cacaatatcg ccccgcaata cgtttactgc
    40981 ataacaggtt gaatgtcgtg gatacgtaca aagcctaact gatccacaga aatacccttt
    41041 aactgtaacg gaatatcaac atcgctgggg gcgaggacgc tggcaggggc gttaatcaat
    41101 tgattctgca cattgatttc ctgaaagttg tctattgttc cctgaatttg cccatattca
    41161 acggttccgc tgaatgcggg taaagggtca ttggattcgc cctgaatacg tagcgtcagg
    41221 gtagtgccat ctgtgtcagg cgtaatattc accagcgaca tacgtaaagt accgatctgg
    41281 ctttccagtc ttgctggtgt ttttgctcca ggcagaaggt aaaccccact gctggatttt
    41341 gcattcagct tgttttgctg agtgattttg accgtttctt tattgagttg cgtcatctcc
    41401 tggttcagcg tgctgacgct gtgtttcatc tgtcgcactt cactttgctg cacacaggcg
    41461 ctaaggctga acaggcttcc cagcaggagc agtcgaaaaa cgttagtatt cataggtcgt
    41521 ccctttctcg tcgcaattag cctaatggta gagggtaaaa gcagtgaaag catcgatcct
    41581 ttatctcaaa agcgttgcgc ctttgttgta tcgtcagttc agggtaaaat agatttctgt
    41641 taaccacctg gtcaggacgc cgtatgcatt gcccattctg tttcgccgtg gacactaagg
    41701 taattgactc tcgtctcgtg ggcgagggtt catccgtacg ccgccgtcgg cagtgtctgg
    41761 tgtgtaatga acgtttcacc acctttgaag tggcggagct ggttatgccg cgtgttgtaa
    41821 aaagcaacga cgtgcgtgaa ccgtttaatg aagagaaatt acgtagcgga atgctgcggg
    41881 cgctggaaaa acgtccggtg agttccgatg acgtcgaaat ggcaatcaat catataaaat
    41941 cgcagctgcg cgccaccggt gagcgcgaag tgccgagcaa gatgattggc aatctggtga
    42001 tggagcaatt gaaaaagctc gataaagtcg cctatatccg ttttgcctct gtctaccgca
    42061 gtttcgaaga tatcaaagaa tttggcgaag agatcgcgcg cctggaggac taagccgtgc
    42121 aggacgagta ttacatggcg cgggcgctaa agctggcgca acgaggacgt tttaccacgc
    42181 atcccaaccc gaatgtcggg tgcgtcattg tcaaagatgg cgaaattgtc ggtgaaggtt
    42241 accatcaacg agcgggtgaa ccgcatgccg aggtacacgc gttgcgcatg gccggcgaaa
    42301 aagccaaagg cgcaacggcg tatgtcacac tcgaaccctg tagccatcat ggtcgtacgc
    42361 caccgtgttg tgatgcatta attgctgcgg gcgtggcgcg cgtggttgct gcaatgcaag
    42421 accccaatcc gcaggttgct ggacgtggac tttaccgtct gcaacaggct ggcattgacg
    42481 tcagccacgg gctgatgatg agtgaagctg agcaattgaa taaaggcttt ctcaagcgga
    42541 tgcgcaccgg ctttccttat attcagttaa aacttggcgc atcgcttgat ggtcgcacgg
    42601 cgatggcgag tggcgaaagc cagtggatca cttcgcctca ggcgcgacgc gacgtacaac
    42661 gactgcgcgc gcaaagtcat gccattttaa ccagcagcgc cacggtgctg gcggatgatc
    42721 cagccttaac agtgcgttgg tctgaactgg atgaacaaac tcaggggctc tacccgcaac
    42781 aaaatctccg tcagccagta cgtattgtga ttgatagcca aaatcgcgtg acgccggaac
    42841 atcgcattgt gcagcagccc ggcgaaacct ggttcgcgcg tacgcaggaa gattctcgtg
    42901 agtggccgga aacggtgcgt accttgctga ttccagagca taaaggtcac ctggatctgg
    42961 ttgtactaat gatgcaactg ggtaaacagc agattaacag catctgggtg gaagcggggc
    43021 caacgctcgc tggcgcattg ctacaggcgg gtttagtcga tgagctgatt gtctatatcg
    43081 cacctaaact attaggcaac gacgcccgtg gattatgcac gctgccaggg cttgagaaat
    43141 tagccgacgc tccccaattt aaattcaaag agatacgtca tgtaggcccg gatgtttgcc
    43201 tgcatttagt gggtgcatga tctcccggct cgaaagggaa gcagcgcacg aaatattatg
    43261 ctaaaatccg cccccctgcg gggccatact cgaacccgaa ggaagaaaat gaacattatt
    43321 gaagctaacg ttgctacccc ggacgctcgc gtcgccatca ccatcgcgcg tttcaacaac
    43381 tttatcaatg acagcctgct ggaaggtgca attgacgcac tgaaacgtat cggtcaggta
    43441 aaagatgaaa acattaccgt tgtttgggtg cctggtgcct atgagctgcc gctggcggcg
    43501 ggtgcactgg ctaaaaccgg taaatacgac gcggtgattg cgctgggtac ggttattcgt
    43561 ggtggcactg cccactttga atatgtcgct ggtggtgcaa gcaacggcct ggcgcatgtt
    43621 gcccaggaca gcgaaattcc ggttgctttt ggtgttctga ccactgaaag cattgaacaa
    43681 gcgatcgaac gtgctggcac caaagctggc aacaaaggtg cagaagctgc actgaccgcg
    43741 cttgaaatga ttaatgtatt gaaagccatc aaggcctgaa attagtaagg ggaaatccgt
    43801 gaaacctgct gctcgtcgcc gcgctcgtga gtgtgccgtc caggcgctct actcctggca
    43861 gttgtcccag aacgacatcg ctgatgttga ataccagttc ctggctgaac aggatgtaaa
    43921 agacgttgac gtcctgtact tccgtgagct gctggccggg gtggcgacta acaccgcata
    43981 cctcgacgga ctgatgaagc cgtacctgtc ccgtctgctg gaagaactgg gccaggtaga
    44041 aaaagcagta ctgcgcattg cgctgtacga gctgtctaaa cgtagcgatg tgccatacaa
    44101 agtggccatt aacgaagcga tcgaactggc gaaatcgttc ggcgcagaag acagccataa
    44161 gttcgtcaac ggcgtactcg ataaagcagc acctgtgatt cgccctaaca aaaagtaata
    44221 tccaagccgg tagattcacg gaagaccgtt ccatgatcgc cggccttttc ttttttatct
    44281 gctgaggcgt aacgtatggc atgtggcgag ttctccctga ttgcccgtta ttttgaccgt
    44341 gtaagaagtt ctcgtcttga tgtcgaactg ggcatcggcg acgattgcgc tcttctcaat
    44401 atccccgaga aacagaccct ggcgatcagc actgatacgc tggtggcggg caaccacttc
    44461 ctccctgata tcgatcctgc tgatctggct tataaagcac tggcggtgaa cctaagcgat
    44521 ctggcagcga tgggggccga tccggcctgg ctgacgctgg cattaacctt accggacgta
    44581 gacgaagcgt ggcttgagtc cttcagcgac agcttgtttg atcttctcaa ttattacgat
    44641 atgcaactta ttggcggcga taccacgcgt gggccattat caatgacgtt gggtatccac
    44701 ggctttgttc cgatgggacg agccttaacg cgctctgggg cgaaaccggg tgactggatc
    44761 tatgtgaccg gtacaccggg cgatagcgct gccgggctgg cgattttgca aaaccgtttg
    44821 caggttgccg atgctaaaga tgcggactac ttgatcaaac gtcatctccg tccgtcgcca
    44881 cgtattttac aggggcaggc actgcgcgat ctggcaaatt cagctatcga tctctctgac
    44941 ggtctgattt ccgatctcgg gcatatcgtg aaagccagcg actgcggcgc acgtattgac
    45001 ctggcattgc tgccgttttc tgatgcgctt tctcgccatg ttgaaccgga acaggcgctg
    45061 cgctgggcgc tctctggcgg cgaagattac gagttgtgtt ttacggtgcc ggaactgaac
    45121 cgtggcgcgc tggatgtggc tctcggacac ctgggcgtac cgtttacctg tatcgggcaa
    45181 atgaccgccg atatcgaagg gctttgtttt attcgtgacg gcgaacctgt cacgttagac
    45241 tggaaaggat atgaccattt tgccacgcca taaagatgtc gcgaaaagtc gcctgaaaat
    45301 gagtaatccg tggcatctgc ttgctgtcgg attcggaagt ggattaagcc cgatcgttcc
    45361 tggcacgatg gggtcgctgg cggcgattcc cttctggtat ctgatgactt ttttgccctg
    45421 gcagctctat tcgctggtgg tgatgctggg gatctgtatc ggcgtctatc tttgtcatca
    45481 aacggcgaaa gacatgggcg tgcacgatca cggcagtatt gtctgggacg aatttattgg
    45541 tatgtggatt acgctcatgg cgctgccgac caatgactgg cagtgggtta ccgccggatt
    45601 tgtgattttc cgtattctgg atatgtggaa gccgtggccg atccgctggt ttgatcgcaa
    45661 tgtacatggc ggcatgggga tcatgattga cgatattgtc gccggggtga tctccgcagt
    45721 catcctgtac tttattggac atcactggcc gctgggtatt ctgtcgtagt tgtgcaccga
    45781 tgcctgatgt gacgcttgtc acgtctcatc aggcctgtat acctatttaa atcctacgac
    45841 cggatgcggt ttatacggcg tttccagctc ggcgatttgt tccggcttca aggtgatatc
    45901 caccgcgttt agcagttcat caagctgttc ctcccgagaa gttccgataa tcggtgcggc
    45961 aatgcccggt ttactcaaca accaggccag cgcaacttgt gctcgcgttg caccaagttc
    46021 ttcactgacg cccgttaagc gttctgcaat ttgtgcgtca ttttcatcgc tttcttggta
    46081 gagatttttc cccacttcat ccgacaccag ccgtgcggtg gtttctcccc aaggacgcgt
    46141 cagacggccc cgcgccagcg ggctccatgg aatcaccgcc acgccttcct gataacacag
    46201 cggcagcatc tcgcgctctt cttcacgata aatcagattg tagtgatcct gcatactgac
    46261 aaactgcgcc cagccgtgct gtttttgtag ttccagtgct tgagcaaact gcgaagcgtg
    46321 catggatgac gcgccgatat aacgcgcttt cccgactttt accacgtcgt tcagggcttc
    46381 cagcgtctct tcgatcggcg tgttgtaatc ccagcgatga atttgcagga tatcgacata
    46441 atccatgccg agacggcgca ggctgtcgtc gatagagcgc aaaatttgtg cacgggataa
    46501 tccttcaggt aaatcaccaa cgcgatggaa cactttggtc gcaacgacca cgtcttcacg
    46561 acgggcgaaa tcccgcagtg cgcgaccgac gatctcttcg ctgctgccat cggaatagct
    46621 attggcggta tcaaagaaat ttatgccgcc ttccagcgca cgtttaatga tgggacggct
    46681 gctctcttcc ggcagtgtcc atgcgtgatt accgcgatct ggctcgccaa aggtcataca
    46741 tccgaggcaa agtcgggaaa cgcgaaggtc ggtttttcct aaggggttgt attgcatgct
    46801 gccactcctg ccatgaataa tttcttaagc atagcaggag tggagtaggg attatgccag
    46861 ccaggctttg attttggctt ccataccggt ggcatcgagg ccgagttcgg cgcgcatttc
    46921 ttcctgagtt ccttgtggaa taaagaagtc cggcaggcca atgttcagca cgggtactgg
    46981 tttacgatgg gccatcaaca cttcgttcac gccgctgcct gcaccgccca taatggcgtt
    47041 ttcttctacg gtaaccagcg cttcatggct ggcggccatt tccagaatta acgcttcatc
    47101 aagcggtttc acgaaacgca tatcgaccag cgtagcgttc agcgattcag cgactttcgc
    47161 cgcttctggc atcagcgtac caaagttaag gatcgccagt ttctcaccac gacgcttcac
    47221 aatgcctttg ccaattggca gtttttccag tggcgtcagt tccacgccaa ctgcgttgcc
    47281 gcgcgggtag cgcaccgcgg acgggccatc gttatagtga tagccggtat agagcatctg
    47341 gcgacattcg ttttcatcgc tcggggtcat aatgaccatt tccggtatgc agcgcaggta
    47401 agagagatca aaagcgccct ggtgggtttg accgtcagcg ccaacaatgc ccgcacggtc
    47461 gatggcgaac aggaccggaa gcttttgaat cgccacgtca tgcagcacct gatcataggc
    47521 gcgttgcagg aaggtggagt agatcgcgac aatgggtttg tagcctccaa tcgccagacc
    47581 cgcagcaaag gttactgcgt gttgctcggc aattgccacg tcaaagtagc gatccgggaa
    47641 tttacgtgaa aactcgacca tgccggaacc ttcacgcatc gccggagtaa tcgccatcag
    47701 cttgttatct ttcgctgcgg tttcgcacaa ccagtcgcca aagatttttg aatagcttgg
    47761 taaaccgccg ctacttttcg gcagacaacc gctggaggga tcaaatttag gcacggcgtg
    47821 gaaggtgatt gggtcttttt ctgccggttc ataaccacga ccttttttgg tcatgatatg
    47881 caggaactgc gggcctttca ggtcgcgcat gttcttaagc gtggtgataa gccccagcac
    47941 atcgtgaccg tccaccgggc cgatgtagtt aaagcccagc tcttcaaaca acgtgccagg
    48001 cactaccatg cctttaatat gttcttcggt acgtttgagc agctctttaa tgggtggcac
    48061 gccagagaaa actttttttc cgccttcgcg cagtgaagag taaagcttac cggaaagcag
    48121 ctgcgccaga tggttgttga gcgcgccaac attttcggaa atcgacattt cattgtcgtt
    48181 gagaaccacc agcatatcag gacggatatc gcccgcgtga ttcatcgctt caaacgccat
    48241 gccagcagta atcgcgccat cgccaatgac acagacggtg cggcgatttt tgccttcttt
    48301 ctcggcagca accgcaatac caattccggc actgatggag gttgatgaat gcccgacgct
    48361 taatacgtca tattcgcttt cgccgcgcca cgggaacggg tgcaggccac ctttctgacg
    48421 gatggtgccg attttgtcgc ggcgcccggt caaaatttta tgcggataag cctgatgccc
    48481 cacatcccag attaactggt caaacggggt attgtagaca tagtgcagcg ccacggtcag
    48541 ttcgaccgtg cccagcccgg aggcgaagtg cccgctggaa cggctcacgc tgtcgagtaa
    48601 atagcggcgc agttcgtcgc agagtttcgg taaactctct ttcggcaaca gtcgtaactc
    48661 ctgggtggag tcgaccagtg ccagggtcgg gtatttggca atatcaaaac tcatcagggg
    48721 cctattaata cttattgttt atttattacg ctggatgatg tagtccgcta gcgcttccag
    48781 tgccgaggta tcgaatgact gttcagtcag ttgtttcagc gactgacggg catcgtcgat
    48841 cagatcccgg gctttcttcc gggcttgctc aagacccaga agtgcagggt aggtactttt
    48901 accaagttgc tggtcggcac cctggcgttt tcccaacgtt gcagtatctc ccaccacatc
    48961 caggatgtca tcctgaacct ggaaggcaag gccgatgctc tctgcgtact tgtcgagtac
    49021 tggcagagca cgacgtcctt tatctccggc gcttaatgca ccaaggcgaa cggcggcgcg
    49081 aatcaatgcg ccggttttat gacgatgaat acgctcaagc gcgtccagag gtacgtgttt
    49141 gccttcagcg tctaaatcta atgcctgacc accgcacatt ccggcaatac cgctggcgct
    49201 cgccaactca gaaatcatcg aaattctgtc gcgatctgac acttccggca tatcggcatc
    49261 gcttagaatc gagaacgcca gcgtttgtaa agcgtcacca gcgagaatcg cgtttgcttc
    49321 gccaaacttc acatggcagg tcggcaaacc gcgacgcaga tcgtcatcat ccatcgccgg
    49381 taaatcatca tgaattaatg agtaagcgtg gatacactct acggcggcag cgggtgcgtc
    49441 cagtgtgttt gtgctaacgc cgaacatatg accagtggca taaaccagga aaggtcgcag
    49501 gcgcttacca cctaataatg cgccatactg catggtttcg accacgggag tgttctgaaa
    49561 gggcagtggg gcgataaaac ggctcagcgc ctggttggcc tgcttaacgc aggcttcgag
    49621 ttgctgcgga aagtccatta ctcattgtcc ggtgtaaaag gggttagaga ggcgtcttca
    49681 ttgtcagaca gcagaatttg tacgcgctgt tcggcttgtt gtaatttagc ctgcccctga
    49741 cgtgccagct gcacgccgcg ttcgaactcg ttcagcgcct cttccagcgg caggtcgcca
    49801 ctttccagac gggttacaat ctgttccagc tcgctcagcg ccttttcaaa gctggcggga
    49861 gcctcatttt tcttcggcat aatgaatgtc tgactctcaa tatttttcgc cccgtcatgg
    49921 taacggactc agggcaaata gcaaataacg cgcaatggta aggtgatgtg cgcagcaaag
    49981 cgatgttagt ggtatacttc cgcgcctgga tgcagccgca ggtgtgggct gctgtatttt
    50041 tccctataca agtcgcttaa ggcttgccaa cgaaccattg ccgccatgaa gtttatcatt
    50101 aaattgttcc cggaaatcac catcaaaagc caatctgtgc gcttgcgctt tataaaaatc
    50161 cttaccggga acattcgtaa cgttttaaag cactatgatg agacgctcgc tgtcgtccgc
    50221 cactgggata acatcgaagt tcgcgcaaaa gatgaaaacc agcgtctggc tattcgcgac
    50281 gccctgaccc gtattccggg tatccaccat attctcgaag tcgaagacgt gccgtttacc
    50341 gacatgcacg atattttcga gaaagcgttg gttcaatatc gcgatcagct ggaaggcaaa
    50401 accttctgcg tacgcgtgaa gcgccgcggc aaacatgatt ttagctcgat tgatgtggaa
    50461 cgttacgtcg gcggcggttt aaatcagcat attgaatccg cgcgcgtgaa gctgaccaat
    50521 ccggaagtga ctgtccatct ggaagtggaa gacgatcgtc tgctgctgat taaaggccgc
    50581 tacgaaggta ttggcggttt cccgatcggc acccaggaag atgtgttgtc gctcatttcc
    50641 ggtggtttcg actccggtgt ttccagttat atgttgatgc gtcgcggctg ccgcgtgcat
    50701 tactgcttct ttaatctcgg cggcgcggcg catgaaattg gtgttcgtca ggtggcgcat
    50761 tatctgtgga accgttttgg tagctcccac cgcgtgcgtt ttgtcgccat taactttgag
    50821 ccggtcgtcg gtgaaattct cgagaaaatc gacgacggtc agatgggcgt tatcctcaaa
    50881 cgtatgatgg tgcgtgccgc gtccaaagtg gcagaacgtt acggcgtaca ggcgctggtt
    50941 accggtgaag cgctcggcca ggtgtccagc cagacgctga ccaacctgcg cctgattgat
    51001 aacgtctccg atacgctgat cctgcgtccg ctgatctctt acgacaaaga gcacatcatc
    51061 aacctggctc gccagattgg caccgaagac tttgcccgca cgatgccgga atattgcggc
    51121 gtgatttcca aaagcccgac ggtgaaagcg gttaaatcga agattgaagc ggaagaagag
    51181 aagttcgact tcagcattct cgataaagtg gtggaggaag cgaataacgt tgatatccgc
    51241 gaaatcgccc agcagaccga gcaggaagtg gtggaagtgg aaaccgtcaa tggcttcggc
    51301 ccgaacgacg tgatcctcga tatccgttct atcgatgaac aggaagataa gccactgaaa
    51361 gtcgaaggga ttgatgtggt ttctctgccg ttctataaac tgagcaccaa atttggcgat
    51421 ctcgaccaga gcaaaaactg gctgttgtgg tgtgagcgcg gggtgatgag ccgcctgcag
    51481 gcgctctatc tgcgcgagca gggctttaac aatgtgaagg tgtatcgccc gtaatatgtg
    51541 gttgtaacgt cgcatctggt cagatgcgac gcttaccgca tccgacacta ctcgtaataa
    51601 ttataaatcc ctgccgccat caccagttgt gatgccactt catgggcttt ctcgcgccca
    51661 accagcaggt cgataatttt cagaccaaag tcgatagctg tacccggccc ctggctggtc
    51721 agcaatttta cccgtgcatc ccagacgacg cgcttgtcct gccattgttc ggcgggaatt
    51781 ttgtctttca gcgttgggaa gccggtcata ttgccaatcg ggaagatatc gtgcgggacc
    51841 agcacggtgg ctggcgcggc gcaaatagcc gcgacgatac gcccggaacg gtggaactgt
    51901 ttaacggttt caaccagcag ggtgctatcg cgaaaacact ctgcgccttt gatgccacca
    51961 ggcagcacaa tcacgtcata ttcgccatca gccacttcga ccagcggcgc atccgccagc
    52021 agcttcacgc cgcgcgagca ggtaatcgcc aggttaccat cgctggcgac gctggcagtg
    52081 gtgactttga taccgccgcg aaccaagagg tcgatagtgg tgacggcttc agtctcttca
    52141 ctaccagggg cgaggcaaac cagtgccgat gcgctcatat tcactctcct ttctttttac
    52201 catttcaaac aggcgggtgt tttccggtac ggcaatccca tgcgcgcggg cgcggcgtaa
    52261 gagaaaacca ttgatatagt cgatttcggt gtggcgcagc gcgcggatat cctgcaacat
    52321 cgacgagata ttttccgctg ttgcatcaat cacctgcatc acgtaatcac gcaaatcttc
    52381 tgctgaagta tgatgccctt cgcgttcgat cactgccgcg acttcttcgc atatctgcat
    52441 aatttcttgc ggatgatgac gtaattcacc attcgggcaa ttccagatgg cggtcagtgg
    52501 attaatcaca cagttgactg ccagcttgcg ccacagctcg gcgcgaatat tgttatgcca
    52561 cgcgacgtca ggcaatacgg tttgcaaaat atccgccaga taactgtaat cgccgtcctg
    52621 ttgccgtgcc ggaccaatat gcgtgatacc gtttgccaca tgaataatga cattgccgtc
    52681 gcggcgggcg gcatgggtgg tggtgcccat cagtaatggc tgctgaatgt tttgcaactc
    52741 ttcgatggtg cccatgccgt tgtgaattaa cagtattggc gtggttacag gcagtgtgga
    52801 cgcgaggctt ttgacggcat cggaaacctg ccatgctttc agcgtcacca ggagcagatc
    52861 gctggtggcg agaaaatcgg gatcgttggc ggtcagcgat tcattaaata tcgaaccatc
    52921 tgtctcaacc agattcacac tacaataagg ttgcggtacg cgcagccagc cctgaacgtc
    52981 gtgaccctgt ttacaaagtg ctgtaagcca taattgccct aaggcaccgc atcccaatac
    53041 ggtaattttc attgttcctc ctcacccgca accactccgg gtgttcaata aggctatccc
    53101 ttaattgtgc atgctgttgc gactatgcac aattaaggga tacgtcctgg tgcaggactg
    53161 ttggttattt aactttgcag gtattatgct tcgcatcaaa aatgaaggga gaggaaaaga
    53221 tgccatcttt cgatattgtc tctgaagttg atcttcagga agcacgtaac gcggtcgata
    53281 acgcgagccg cgaagtggag tcccgttttg acttccgtaa cgttgaagcc tcatttgagc
    53341 tgaatgacgc cagcaaaacc atcaaagtgt tgagcgagtc cgacttccag gtcaatcagt
    53401 tgctggatat tctgcgtgcc aagttgctga agcgcggcat tgaaggcagt tcactggatg
    53461 taccggaaaa tatcgttcat agcggtaaaa cctggtttgt ggaagcgaaa ctgaaacagg
    53521 gcattgagag cgcgactcag aagaaaatcg tcaaaatgat caaagacagc aaactgaaag
    53581 tgcaggcgca aattcagggc gatgagatcc gtgtgacggg caaatctcgt gatgatttac
    53641 aggctgtcat ggcgatggta cgtggtggcg atctgggtca gccgttccag ttcaaaaact
    53701 tccgcgatta atcgcgacaa cctgcgcttt gttcatgtca gatgcggcat gaacgcctga
    53761 ttcggcctac aaaggtttgt aactcaggaa cttagtaggc ctgataagcg tagcgcagca
    53821 ggcaatttcg cctcgctttt atgcctggcg aattgcctgt tcaacctcaa agcgattcgt
    53881 cactttgctg tcgattttca cataagctga atgttcttct tctgcaatca acacttcttt
    53941 gatgccttca gtttccagca aacgcacttt taacgcctcg tttgcggcaa tgttcgccgg
    54001 gatttcaatg cgcaagctgc tgacatacgg cggttctttc atggtactgg cgactgccag
    54061 ccacactgcg gccagcattg cgccagcgag aaatactccc tgaccgtcaa acatgccgtc
    54121 aatccagccg cccagcgaac cgccaatcgc cacgccaaga aactggctgg tggagtaaac
    54181 acccatcgcc gtacctttgt aacctgctgg cgattcttta ctgataagtg aaggcagaag
    54241 ggcttccatc aaattaaacg ccacaaagaa aagctgcacg ccgaccacca gttgccagaa
    54301 ctgcgtttgt gcgttccaca acacaatttc cgcaaccacg atcaacccga cgcagaagac
    54361 aaagacttgc ttcattttgc gcttaacttc agcgtagata atgaaaggca cgaccgagcc
    54421 aaaggcgatt aacatcgttg ccaggtagac cttccagtgt tcagccgccg ggaaccccgc
    54481 atcagccatc tgtccgggca gggcaacaaa ggtcgacatc agcaaaatat gcagacacat
    54541 aatgccaaag ttgagtttca gcagccgcgg ttccgccagc actttactga aactgccttt
    54601 taccattccg gactcacgat taagtacatg agtgctactg ttgggcacaa cccaaatggt
    54661 caacgcaatg ccggttgttg ccagaatagc gatcatccag aacagcacgt gcagcccaag
    54721 tttgtgagtg atgatcgggc caagcaccat cgcaatggca aaggtaatgc caaagctcac
    54781 gccgataaac gccatcgctt tggtgcggtt ttgttcgcgc gtgagatcgg aaagcagcgc
    54841 cataacggct gcggcaatcg caccggagcc ttgtagcgcc cggcccagaa taattcccca
    54901 gatggagtca gagagcgcag cgataacgct accggcggca aacaccgcca gcccaccgac
    54961 aattaatggt ttgcgaccaa tgcggtctga aagcaggcca aacggaatct gaaaaacggc
    55021 ctgagtcaga ccataaatac caatggcaat accgattaat gcttcgctgg caccttgcag
    55081 agccatgccg tacgtggtca gaaccggcag aaccatgaac atgcccagca tgcgtaatga
    55141 aaatacggtc cctaaacccc aggtcgcgcg ccgctcacct ggcgtcattt tataatcgtt
    55201 cattaccacc tctgttttaa attcgcgact agtgtaaagc ggcaaacgaa tggggtaaac
    55261 atgcggattt tttagtaaat atttcgagag ggatatgatt ctaatgctaa gaaaaaaggt
    55321 gccgtagcac ctttttaact gagaggttgt gttaccacac agcagccagc agcgtatgcg
    55381 agtccggcac cataaaatca acggacatca tcaccgagag ggcagtgata gcgatgatag
    55441 agaaaccgaa cagcttgcgc gcccagattc tgtcatcagc aactttatag ccgcgcagag
    55501 ccatgcctaa ccaccagacg ctcaccgcag cggcgaccac cagatattta tacccagcgt
    55561 agccgccaag agagagcatc agcgtggcaa cggcaaaggc gatgatatac agcgtgatgt
    55621 gattcttcgc caccgaaatg cctttcacca ccggcagtac cggaatgttt gccgcctgat
    55681 aatccttaaa gcggaaaatg gctatggcat aagagtgagg catctgccac aggctgaaga
    55741 tagccaacag gatcgctgcg ccgctatcga actcgccggt taccgcacag taaccgatca
    55801 ccggaggcgc agcgccggag agcgaaccaa tcaatgtgcc gtagacagaa tgacgtttca
    55861 tgtacaggct ataaacgccg acataaacca caaagcccat cacccccagc cagcaggcca
    55921 gcggattcgc gccaaaccac agcagcataa agccagcaat acccagcaag gtggcgtaca
    55981 ccagcgagac agcaggagag atcaggcctt taaccagcac ccgattcttc gtcctttcca
    56041 tctttctgtc gatatccctg tcgatgtagt tgttaaacac acaacccgac gccacaacca
    56101 gtgacacccc aaccagcgtg tagataaaca ggggataatc aatgctgccc tttgaggcca
    56161 gcaagaatcc cccaatcacc gagatcaggt tgccaaagat gatgcctggt ttcgttactt
    56221 gcaggtattg cttaaatatc ataaccgccg ctcttagtgc atcatcatgt tgtagttgag
    56281 gttccacata atccagatgg agcccacaac caggatggcg atgattagca cggtgaagac
    56341 aaacgccgtc atattccagc cttcatctga tttggtattc atgtgcagga agcacaccag
    56401 atgcaccaga atttgtacca ctgccattgc caggattgtt cccagaatta cggccggaga
    56461 ggcagcccct gtcatcacca tccagaacgg aattaccgtc aggattatcg acaggataaa
    56521 gcctgtcatg taggtcttta cgctgccatg ggatgcgccg ctgcttgcgt tagaatgact
    56581 cattacatcg cccccatcag ataaacaaca gtgaacacac agatccaaac cacatccagg
    56641 aagtgccaga acaggctcag gcacatgatg cgggtacggt tagtgctggt caggccgcga
    56701 cgggcgattt gcaccatcag caccgccatc cagataagac cggaagtgac gtgcagaccg
    56761 tgcgtgccga ccagcgcaaa gaatgctgac aggaagccgc tgcgatccgg acccatgccg
    56821 ttaacaatca ggtgatggaa ttcatagatt tccatcccga taaatccggc accaaacaac
    56881 catgtcaacg ccagccagga gatcacctgg cttttgttgt ttttgtacat ggcgatagcc
    56941 gccatgccat aggtgatgga gctgaacaac agcaagaaag tttcaaccag aacgaacggc
    57001 agttcgaaaa tgtccttacc tgtcgggccg cctgcggtgc cgttcaccag aacggcatag
    57061 gtagcaaaca agatagagaa cagaatgcag tcgctcatca ggtagatcca aaatccgaaa
    57121 attttggttc cgcctgcatc gtggtgcccg tgttcgtgcg cgtgggcagt cgcgtgcgtc
    57181 aaagtatcag ttgccatttt tcagccctgc cttagtaatc tcatcgaaat gctggttttc
    57241 cagtttttcg atttctgcca ccggcacgta gtaatccacg tcctcgtcga agcttttcac
    57301 gatccaggtg atgatcatgc ctgcgaagcc aacaatcgct agccaccaga tatgccagat
    57361 catggcgaaa ccgaagatgg tggagaaagc cgcaatgacg ataccggcac cgctgttttt
    57421 cggcatatga atttcttcat agtggtcagg ctttttgtac gcttcgcctt tctctttcat
    57481 ttcccagaat gcatcacgtt cgtgaacgtg cggcacaacg gcaaagttat agaacggagg
    57541 cggggaagag gttgcccact ccagcgtacg gccaccccac gggtcgccag tcaggtcacg
    57601 gttctggtcg cggtcacgaa tagaaacgta tatctgaata acgaggcaga gaatacccag
    57661 cgcaatcagt accgcaccgc tggctgcaat catcagcatg gtgtggaact gcgggtcaat
    57721 ctgctggctc aaacgacggg tcatgcccat gaagcccagc gcatacagtg gcataaaggc
    57781 aacgaagaag ccgatgatcc agaaccagaa cgcgcgttta ccccaggttt cgttcagttt
    57841 gaaaccgaac gctttaggcc accagtaggt catccctgcg aagcagccga agaccacgcc
    57901 gccgatgatc acgttatgga agtgcgcaat caggaacagg ctgttatgca gaacgaagtc
    57961 cgcgcccggt actgccagca gcacgccagt cataccgcct accgagaagg taacgataaa
    58021 accgatggtc cacagcatcg cagaatggaa cacgatgcgg ccctgataca tggtgaacag
    58081 ccagttgaag atcttcaccc cggtagggat ggcgataatc atcgtggtga taccaaagaa
    58141 ggcgtttacg ttcgcgcccg cacccatcgt aaagaagtgg tgcagccaga cgatgaacga
    58201 cagcacggtg atacagacgg ttgcccatac cagcgaggta taaccaaaca gacgtttacg
    58261 cgagaaggtt gccgcaattt cggagaacac accgaataca ggcaggatca agatgtaaac
    58321 ttccgggtgg ccccaggccc aaatcaggtt gatatacatc atcatgttgc cacccatatc
    58381 gttggtaaag aaatgggtgc ccagatagcg atccagggtc aacaacgcga cggtaaccgt
    58441 cagaattggg aaggaagcaa taatcagtac gtttgcgcac agtgatgccc aggtaaatac
    58501 tggcatcttg aacatggtca tgcccggtgc gcgcatcttc agaatggtaa cgaagaagtt
    58561 gataccggta agcgtcgtac ctataccgga tagctggaga ctccatatcc agtaatcgac
    58621 accgactccc ggactgtact ctattcccga tagcggtgga taggccagcc agccggtctg
    58681 cgcaaattcg cccacgccga gagaaacgtt aaccagaatc acaccaacaa cggtaaacca
    58741 gaagcttaag ttgttgagga acgggaacgc aacgtcacgc gcgccgatct gcagcggaac
    58801 caccaggttc atcagaccga taacgaaagg catcgccacg aagaagatca tgatcacgcc
    58861 gtgtgcggtg aagatctgat cgtagtggtg aggtggcagg aagcccgctt cgcccgcaga
    58921 ggcaagggcc tgctgactac gcatcataat ggcgtcagca aaaccacgca gcaacatcac
    58981 aatcgccacg atgatataca tgataccgag acgtttatgg tcaacggagg tcagccactc
    59041 tttccacagg taggtccact taccgaagta agtgatcagg ccaacgagcg ccagacctcc
    59101 caaaataatg ccagcgatcg taaccatgac gataggttca tggaacggga ctgcatcaag
    59161 tgataatttt ccgaacatct ttattcttcc tcaacccctt taatgggcgg attccgcgtg
    59221 gctcatgtcc atgccttcca taccttcatg tgcgctgtgc tcaccttctg gctgggtcat
    59281 gtccatgctc ttaccgtgag ccataaactt gttaatcaca tcggcaaaca agtctggttt
    59341 cacgttggag aaatattcca cctggttgta ttcgctaggc gcggccagtt tttcgaacgc
    59401 tgccatgtca gacatgctgt tcggcgactg tttcgctttt gcgacccatt ggtcgaatgc
    59461 ggcgcgatcc ggtgttgcaa tagctttgaa cttcatgcct gagaagcccg ggccgctgta
    59521 gctggcggag ataccgtcat aagtaccggg ttcgttggcg atcagatgca ggcgagtctg
    59581 cataccggcc atggcataaa tctggctacc cagacgcgga atgaagaagg agttcatcac
    59641 ggagttggag gtcactttga agtacaccgg agtgttcgcc gggaaagcga tttcattcac
    59701 ggttgcaatg ccctgttccg ggtagatgaa gaaccatttc cagtccatgg aaaccacttc
    59761 gatggtaatg ggcttctcgt cgtgtgccag cggcttgcta ggctcaagag cgtgagtggt
    59821 tttccaggtc agtaccgcaa ggaagatgat gattaagata ggtaccgtcc agaccacagc
    59881 ttccacttta ttggagtgtg accagttcgg gctgtactta gcatctttat tgctcgcacg
    59941 gtacttccag gcgaaaccaa cagccatcaa gattgcggga ataacgacaa tcaacatcag
    60001 gccaaatgcc gtcagtatca gtgaacgttg ctccagacca atctgtcctt tgggatctaa
    60061 cagcgcagaa ttacagccac tgagcaatac agtgcctgca aataatgaca accatcccaa
    60121 acttttattg tatttcctga gtctcattta acgacctcaa ttccacggga tctggtggcg
    60181 tttaaagtgt gtgggcattt tacgggaagg ttacattact gtaaacatga ttaaattcct
    60241 gttacttgga tttggctatc aggtcacata tgttgcaaaa catatcaagt tgattttaag
    60301 aagctgttgc aaaagggcgt tataacgaaa gggaagtgca gaaggagttt gggcgggcaa
    60361 ttggtataat caatataaaa taaaacaatt atttaacaaa taactatcat tagggtgaca
    60421 actgggtggt gagaaaataa ggactcatca gctgaatcgt gtaaaaaaaa tagaattcat
    60481 aaatggcgtc aataatttcc agacgctaag ccgcacaaaa gaacaaatat caataagcga
    60541 tgctgatgtt tatttagccg taataattac ggcgagtgat tactacagct aaataatatt
    60601 tacagattac gtcagatgtg tttttcgtag cgccagataa tccagcaaac caccaagcac
    60661 gacgccagag agggcgacta aaaccccgac ttccagcagc gcaggcagga aagagaagtg
    60721 cgtcaaatcc agcgcgtcca tcgtcaacag cagtaaccac acggccaaca ggctgatgcc
    60781 cgccgccagt gtccacatgg caaaggcata acctgcagga tattcggtac gggagataaa
    60841 gttgtcattt actcgtgtat attcaagcgt ctggcggcaa accagcagca aaataagccc
    60901 tggtacggca gcggcgacgg agaatagata gaatgtcgac cagccgtgtg cttcaacaaa
    60961 ccaacccgcc acggggccga cataaactcg ccctacagca gaaagcgctg agagcagggc
    61021 aaattgagta gcggaaaatg acttattaca cagcgtcatt aacagcgcga caaaggctga
    61081 tgtacccatc ccgccacaga ggttttcgaa aaagacggct gcacccatgc tgtagagatg
    61141 cttatcagta atcgacagca gccagtaacc ggcgttagat gcaccttgta aaatgccgaa
    61201 aatcagcagt gcacggaaca gcgacaggcg ctgcatcaaa atcccaccgt acaatgcgcc
    61261 aacaatggtc gccagtaagc caagcgtttt gttaaccacg cctacttcac ccgcatcaaa
    61321 cccgacgccg cgaatcaaaa acgtggttgt caggctcata gcgaatgcgt cgcccagctt
    61381 atacagcacg ataagaagca aaataagcca ggcattattg cgaccaaaga aatctcgcag
    61441 aggtgcaaca accgcttgtt ccagcgtttt gggcacagga atggtgtcgg tgggttctgg
    61501 tgcaagcaac gtcgcgataa tacaggggat caacagcgcc gccatcaacc agtacatgcc
    61561 ctgccagccc agccatttat ctgccagcca cagggctaag ccgccggaaa ccagcatccc
    61621 taaacggtaa cccagcacgc tgattgccgc gcccgcacca cgttcttctg ccgggagcac
    61681 atcggttttc cacgcatcga agacaatatc ctgggaggca gagcaaaaag cgatcaccac
    61741 cgccagtgcc gccatccagc ggagctgggt gcctggttcg agaaaaccca tcgccgcaat
    61801 ggcgactaat aacagaattt gcgtggcgag cagccaaccg cgccgccgcc cgaaaaatgg
    61861 gggcgtgtag cggtccatca gtggtgacca gaggaattta aaaacgtaag cctggcctac
    61921 cagagagaag aaaccaatgg ttttgagatc gatattctcg accgtcatcc aggcctgtaa
    61981 ggtgccggac gtcagggcga gcggtagccc ggaagcaaaa cccaggatca gcaatatggc
    62041 tgaacgcggc tgttgaaaaa tacgtaaata ttgactggac atgggcgtct acaggcccgg
    62101 cttgcaccgg gccagagggc agaaattaac gcgcgttctg cttgatgaat tcgtggatgc
    62161 tggtgtcctg agacatatca gcgatggtat cggtcagcac actgttaacc gcatcggcga
    62221 tatttttgtt ggaggcctgg aacgcacctt caacgttgta gctggcacga tagtttttgg
    62281 tcattttgtt gccattctgc gcggtagcga tgatggcgat atccgctttg gtcgcgatgt
    62341 tgtagcgcac gttgccctgg gacacgtcag catacagttg gctaacgatg atttgcagat
    62401 taaccgggcc attcggacca accatgtatc cacgggcggt catttgtttt tccagcactt
    62461 cttgcagcag gaaacgcaga tcgcgggagg cggtcagggt aacgatttga ttatcgcggg
    62521 tgacttttgc cagcgcctga tcggtacgct gatcggcacc attaatgctt acggtgacgc
    62581 ccatcaggct tggatcctgc tgtggcagtg taatcgtcgg ggaaacttcg atagttgttg
    62641 gcggttttgc gcatcctgca agcataaaca gagcaactaa cgggaagagg atttttttga
    62701 acatgttcgg gctctcagag actcttaagc gtgtttggta aaaattcccg ccatcataac
    62761 attgccaacg gcgaggggaa gtgggtaagg catgtaaatt catcatgttg acgaaataat
    62821 cacccctggt aaaagaaacg ctgatgcgag gcctgtgttt caatctttaa atcagtaaac
    62881 ttcatacgct tgacggaaaa accaggacga aacctaaata tttgttgtta agctgcaatg
    62941 gaaacggtaa aagcggctag tatttaaagg gatggatgac atctcagcgt tgtcggagga
    63001 gatatttcat gatgatacgt gagcggatag aagaaaaatt aagggcggcg ttccaacccg
    63061 tattcctcga agtagtggat gaaagctatc gtcacaatgt cccagccggc tctgaaagcc
    63121 attttaaagt tgtgctggtc agcgatcgtt ttacgggtga acgttttctg aatcgtcatc
    63181 gaatgattta cagtacttta gcggaggaac tctctactac cgttcatgcg ctggctctgc
    63241 atacttacac tattaaggag tgggaagggt tgcaggacac cgtctttgcc tctcctccct
    63301 gtcgtggagc aggaagcatc gcgtaaaaac gcatttgcaa ctgtcggcgc ttttccagta
    63361 tgttgctaaa gattttatga aaaacggcct gcgggccgtt ttgttttgtc tggattttgc
    63421 gctttttgcc cagcattcag acgaaaatcg cccgggaatt gtgaaaaaat acgcgacagc
    63481 gcgcaataac cgttctcgac tcataaaagt gatgccgcta taatgccgcg tcctatttga
    63541 atgctttcgg gatgattctg gtaacaggga atgtgattga ttataagaac atcccggttc
    63601 cgcgaagcca acaacctgtg cttgcggggt aagagttgac cgagcactgt gattttttga
    63661 ggtaacaaga tgcaagtttc agttgaaacc actcaaggcc ttggccgccg tgtaacgatt
    63721 actatcgctg ctgacagcat cgagaccgct gttaaaagcg agctggtcaa cgttgcgaaa
    63781 aaagtacgta ttgacggctt ccgcaaaggc aaagtgccaa tgaatatcgt tgctcagcgt
    63841 tatggcgcgt ctgtacgcca ggacgtcctg ggcgacctga tgagccgtaa cttcattgac
    63901 gccatcatta aagaaaaaat caatccggct ggcgcaccga cctatgttcc gggcgaatac
    63961 aagctgggtg aagacttcac ctactctgta gagtttgaag tttatccgga agttgaactg
    64021 cagggtctgg aagcgatcga agttgaaaaa ccgattgttg aagtgaccga cgctgacgtt
    64081 gacggcatgc tggatactct gcgtaaacag caggcaacct ggaaagaaaa agacggcgct
    64141 gttgaagcag aagaccgtgt gaccatcgac ttcaccggtt ctgtagacgg agaagagttc
    64201 gaaggcggta aagcgtctga tttcgtactg gcgatgggtc agggtcgcat gatcccgggc
    64261 tttgaagacg gtatcaaagg ccacaaagct ggcgaagagt tcaccatcga cgtgaccttc
    64321 ccggaagagt accacgcaga aaacctgaaa ggtaaagcag cgaaattcgc tatcaacctg
    64381 aagaaagttg aagagcgtga actgccggaa ctgactgaag aattcatcaa acgtttcggc
    64441 gttgaagatg gttccgtaga aggtctgcgc gctgaagtgc gtaaaaacat ggagcgcgag
    64501 ctgaagagcg ccatccgtaa ccgcgttaag tctcaggcga tcgaaggtct ggtaaaagct
    64561 aacgacatcg atgtaccggc tgcgctgatc gacagcgaaa tcgacgttct gcgtcgccag
    64621 gctgcacagc gtttcggtgg caacgaaaaa caagctctgg aactgccgcg cgaactgttc
    64681 gaagaacagg ctaaacgccg cgtagttgtt ggcctgctgc tgggcgaagt tatccgcacc
    64741 aacgagctga aagctgacga agagcgcgtg aaaggcttga tcgaagagat ggcttctgcg
    64801 tacgaagatc cgaaagaagt tatcgagttc tacagcaaaa acaaagaact gatggacaac
    64861 atgcgcaatg ttgctctgga agaacaggct gttgaagctg tactggcgaa agcgaaagtg
    64921 actgaaaaag aaaccacttt caacgagctg atgaaccagc aggcgtaatt tacgtagcat
    64981 aacgcgctaa attcgcacaa aggcccgtca ccgccaggtg gtgggctttt ttttgtcatg
    65041 aattttgcat ggaaccgtgc gaaaagcctc tttcggtgtt agcgtaacaa caaaagattg
    65101 ttatgcttga aatatggtga tgccgtaccc ataacacagg gactagctga taatccgtcc
    65161 ataaggttac aatcggtaca gcaggttttt tcaattttat ccaggagacg gaaatgtcat
    65221 acagcggcga acgagataac tttgcacccc atatggcgct ggtgccgatg gtcattgaac
    65281 agacctcacg aggtgagcgc tcttttgata tctattctcg tctacttaag gaacgcgtca
    65341 tttttctgac tggccaggtt gaagaccaca tggctaacct gattgtggcg cagatgctgt
    65401 tcctggaagc agaaaaccca gaaaaagata tctatctgta cattaactct ccaggcgggg
    65461 tgattactgc cgggatgtct atctatgaca ccatgcagtt tatcaagcct gatgtcagca
    65521 ccatctgtat gggccaggcg gcctcgatgg gcgctttctt gctgactgca ggggcaaaag
    65581 gtaaacgttt ctgcctgccg aattcgcgcg tgatgattca ccagccgttg ggcggctacc
    65641 agggccaggc gaccgatatc gaaattcatg cccgtgaaat tctgaaagtt aaagggcgca
    65701 tgaatgaact tatggcgctt catacgggtc aatcattaga acagattgaa cgtgataccg
    65761 agcgcgatcg cttcctttct gcccctgaag cggtggaata cggtctggtc gattcgattc
    65821 tgacccatcg taattgatgc cagaggcgca actgtgccgc tatacttatc cagggcggca
    65881 caacgctgta agcggcttgc gcctgagaat ggcatttgcg tcgtcgtgtg cggcacaaag
    65941 aacaaagaag aggttttgac ccatgacaga taaacgcaaa gatggctcag gcaaattgct
    66001 gtattgctct ttttgcggca aaagccagca tgaagtgcgc aagctgattg ccggtccatc
    66061 cgtgtatatc tgcgacgaat gtgttgattt atgtaacgac atcattcgcg aagagattaa
    66121 agaagttgca ccgcatcgtg aacgcagtgc gctaccgacg ccgcatgaaa ttcgcaacca
    66181 cctggacgat tacgttatcg gtcaggaaca ggcgaaaaaa gtgctggcgg tcgcggtata
    66241 caaccactac aaacgtctgc gcaacggaga taccagcaat ggcgtcgagt tgggcaaaag
    66301 taacattctg ctgatcggtc cgaccggttc cggtaaaacg ctgctggccg aaacgctggc
    66361 gcgcctgctg gacgttccgt tcaccatggc tgacgcaacc acgctgaccg aagccggtta
    66421 tgtgggcgaa gacgttgaaa acatcattca gaagctgttg cagaagtgcg attacgacgt
    66481 acagaaagcg cagcgcggga ttgtctacat cgatgaaatc gacaagattt ctcgtaagtc
    66541 agacaacccg tccattaccc gagacgtttc cggtgaaggc gtacagcagg cactgttaaa
    66601 actgatcgaa ggtacggtag ctgctgttcc gccgcaaggt gggcgtaaac atccgcagca
    66661 ggaattcttg caggttgata cctctaagat cctgttcatc tgtggcggcg catttgctgg
    66721 cctggataaa gtgattgcca atcgtgttga aaccggctcc ggcattggtt ttggcgcgac
    66781 ggtgaaagcc aagtccgaca aagccagcga aggtgaactg ctggcgcagg ttgaaccgga
    66841 agatctgatc aagtttggtc tgatccctga gttcattggt cgtctgccgg ttgtcgcaac
    66901 gttgaatgaa ctgagcgaag aagctctgat tcagatcctc aaagagccga aaaacgccct
    66961 gaccaagcag tatcaggcgc tgtttaatct ggaaggcgtg gatctggaat tccgtgacga
    67021 ggcgctggat gctatcgcta agaaagcgat ggcgcgtaaa accggtgccc gtggcctgcg
    67081 ttccatcgta gaagccgcac tgctcgatac catgtacgat ctgccgtcca tggaagatgt
    67141 cgaaaaagtg gttatcgacg agtcggtaat tgatggtcaa agcaaaccgt tgctgattta
    67201 tggtaagccg gaagcgcaac aggcatctgg tgaataatta accattccca tacaattagt
    67261 taaccgaaaa ggggggattt tatctcccct ttaatttttc ctctattctc ggcgttgaat
    67321 gtgggggaaa catccccata tactgacgta catgttaata gatggcgtga agcacagtcg
    67381 tgtcatctga ttacctggcg gaaattaaac taagagagag ctctatgaat cctgagcgtt
    67441 ctgaacgcat tgaaatcccc gtattgccgc tgcgcgatgt ggtggtttat ccgcacatgg
    67501 tcatcccctt atttgtcggg cgggaaaaat ccatccgttg tctggaagcg gcgatggacc
    67561 atgataaaaa aattatgctg gtcgcgcaga aagaagcttc aacggatgag ccgggtgtaa
    67621 acgatctttt caccgtcggg accgtggcct ctatattgca gatgctgaaa ctgcctgacg
    67681 gcaccgtcaa agtgctggtc gaggggttac agcgcgcgcg tatttctgcg ctctctgaca
    67741 atggcgaaca cttttctgcg aaggcggagt atctggagtc gccgaccatt gatgagcggg
    67801 aacaggaagt gctggtgcgt actgcaatca gccagttcga aggctacatc aagctaaaca
    67861 aaaaaatccc accagaagtg ctgacgtcgc tgaatagcat cgacgatccg gcgcgtctgg
    67921 cggataccat tgctgcacat atgccgctga aactggctga caaacagtcc gttctggaga
    67981 tgtccgacgt taacgaacgt ctggaatatc tgatggcaat gatggaatcg gaaatcgatc
    68041 tgctgcaggt tgagaaacgc attcgcaacc gcgttaaaaa gcagatggag aaatcccagc
    68101 gtgagtacta tctgaacgag caaatgaaag ctattcagaa agaactcggt gaaatggacg
    68161 acgcgccgga cgaaaacgaa gccctgaagc gcaaaatcga cgcggcgaag atgccgaaag
    68221 aggcaaaaga gaaagcggaa gcagagctgc agaagctgaa aatgatgtct ccgatgtcgg
    68281 cagaagcgac cgtagtgcgt ggatatatcg actggatggt acaggtgccg tggaatgcgc
    68341 gtagcaaggt caaaaaagac ctgcgtcagg cgcaggaaat ccttgatacc gaccattatg
    68401 gtctggagcg cgtgaaagat cgtatccttg agtatcttgc ggttcaaagc cgtgtcaaca
    68461 aaatcaaggg tccgatcctc tgcctggtag ggccgccggg ggtaggtaaa acgtccctgg
    68521 gtcagtccat cgccaaagcc accgggcgta aatatgtccg tatggcgctg ggcggcgtgc
    68581 gtgatgaagc ggaaatccgt ggtcaccgcc gtacttacat cggttctatg ccgggtaaac
    68641 tgatccagaa aatggcgaaa gtgggcgtga aaaacccgct gttcctgctc gatgagatcg
    68701 acaaaatgtc ttctgacatg cgtggtgatc cggcctccgc actgcttgaa gtgctggatc
    68761 cagagcagaa cgtagcgttc agcgaccact acctggaagt ggattacgat ctcagcgacg
    68821 taatgtttgt cgctacgtcg aactccatga acattccggc accgttgctg gatcgtatgg
    68881 aagtgattcg cctctccggt tataccgaag atgaaaaact gaacatcgcc aaacgtcacc
    68941 tgctgccgaa gcagattgaa cgtaatgcat tgaaaaaagg tgagctgacc gtcgacgata
    69001 gcgccattat cggcattatt cgttactaca cccgtgaggc gggcgtgcgt ggtctggagc
    69061 gtgaaatctc caaactgtgt cgcaaagcgg ttaagcagtt actgctcgat aagtcattaa
    69121 aacatatcga aattaacggt gataacctgc atgactacct cggtgttcag cgtttcgact
    69181 atgggcgcgc ggataacgaa aaccgtgtcg gccaggtaac cggtctggcg tggacggaag
    69241 tgggcggtga cttgctgacc attgaaaccg cgtgcgttcc ggggaaaggc aaactgacct
    69301 ataccggttc gctcggcgaa gtgatgcagg agtctattca ggcggcgtta acggtggttc
    69361 gtgcgcgtgc ggaaaaactg gggatcaacc ctgattttta cgaaaaacgt gacatccacg
    69421 tccacgtacc ggaaggtgcg acgccgaaag atggtccgag tgccggtatt gccatgtgca
    69481 ccgcgctggt ttcttgcctg accggtaacc cggttcgtgc cgatgtggca atgaccggtg
    69541 agatcactct gcgtggtcag gtactgccga tcggtggttt gaaagaaaaa ctactggcag
    69601 cgcatcgcgg cgggattaaa acagtgttaa ttccgttcga aaataaacgc gatctggaag
    69661 agattcctga caacgtaatt gccgatctgg acattcatcc tgtgaagcgc attgaggaag
    69721 ttctgactct ggcgctacaa aatgaaccgt ctggcatgca ggttgtgact gcaaaatagt
    69781 gacctcgcgc aaaatgcact aataaaaaca gggctggcag gctaattcgg gcttgccagc
    69841 ctttttttgt ctcgctaagt tagatggcgg atcgggcttg cccttattaa ggggtgttgt
    69901 aaggggatgg ctggcctgat ataactgctg cgcgttcgta ccttgaagga ttcaagtgcg
    69961 atataaatta taaagaggaa gagaagagtg aataaatctc aattgatcga caagattgct
    70021 gcaggggctg atatctctaa agctgcggct ggccgtgcgt tagatgctat tattgcttcc
    70081 gtaactgaat ctctgaaaga aggggatgat gtagcactgg taggttttgg tacttttgcc
    70141 gttaaggaac gtgctgcccg tactggccgc aacccgcaga ccggtaaaga gatcaccatc
    70201 gctgctgcta aagtaccgag cttccgtgca ggtaaagcac tgaaagacgc ggtaaactaa
    70261 gcgttgtccc cagtggggat gtgacgaagt tcaagggcgc atctactgat gtgccttttt
    70321 tatttgtatt cggtgacttt ctgcgtcttg tgggctgaca attgcccccg tttcttgtca
    70381 caataggcct ttgcgcgcat cgatacgttg cgtgaggtac acagtcatct acagcggagt
    70441 gttgttacac catgatggac agcttacgca cggctgcaaa cagtctcgtg ctcaagatta
    70501 ttttcggtat cattatcgtg tcgttcatat tgaccggcgt gagtggttac ctgattggcg
    70561 gaggcaataa ctacgccgca aaagtgaatg accaggaaat cagccgtggg caattcgaga
    70621 acgccttcaa cagcgagcgt aatcgcatgc agcaacagct gggcgatcaa tactccgagc
    70681 tggcagcgaa cgaaggctat atgaaaaccc tgcgtcaaca ggtgctgaat cgtctgatcg
    70741 acgaggcgct tctggatcag tacgctcgtg agctgaaact gggtatcagc gatgagcagg
    70801 ttaaacaggc gattttcgcg accccagcct tccaggttga cggcaaattt gataacagcc
    70861 gctataacgg tatcctcaac cagatgggga tgaccgccga tcagtacgcc caggcgctgc
    70921 gtaaccagct cactacccaa cagctgatta acggcgttgc cggtaccgat tttatgctga
    70981 aaggtgaaac cgacgagctg gcggcactgg tagctcaaca acgcgtggtg cgtgaagcgg
    71041 ctatcgatgt taacgcgctg gcggcgaagc agcctgtgac cgaacaggaa attgccagct
    71101 actacgaaca aaacaaaaac aatttcatga cgccggaaca attccgcgtg agttacatca
    71161 agctggatgc cgcgacgatg cagcaaccgg ttagcgatgc ggatatccag agctactacg
    71221 atcagcatca ggatcaattc acccagccgc agcgtacccg ttacagcatc atccagacca
    71281 aaactgaaga tgaagcgaaa gcggtacttg atgagctgaa taagggcggt gattttgctg
    71341 cattagccaa agaaaaatct gccgatatta tctctgcccg taacggcggt gatatgggtt
    71401 ggttagaaga tgccactatc ccggacgaac tgaaaaatgc gggtctgaaa gaaaaaggcc
    71461 aactgtctgg tgttatcaaa tcttcggtcg gtttcctgat tgtacgtctg gacgacattc
    71521 agccagcgaa agtgaaatcg ttagacgaag tacgtgacga cattgcggcg aaagtgaaac
    71581 acgaaaaagc cctcgatgcg tactacgcgc tgcagcagaa agtgagcgat gcggcaagca
    71641 acgacaccga gtctctggcc ggtgcagagc aagctgccgg cgttaaagcc actcagacgg
    71701 gttggttcag caaagataac ctgccggaag agttgaactt caagccagtt gccgacgcta
    71761 tcttcaacgg cggtctggta ggtgaaaacg gcgcgccggg catcaactct gacatcatca
    71821 ccgtagacgg cgaccgcgca ttcgtgctgc gcatcagcga gcacaaaccg gaagcggtga
    71881 aaccgttggc agatgttcag gaacaagtta aggcactggt tcagcacaac aaagctgaac
    71941 aacaggcgaa agtggatgct gagaaactgc tggttgattt gaaagccggc aaaggtgcgg
    72001 aagcgatgca ggctgccggt ctgaaatttg gcgagccgaa aaccttaagc cgttccggtc
    72061 gtgacccgat tagccaggct gcgtttgcac tgccgctgcc agcgaaagac aaaccgagct
    72121 acggtatggc gaccgatatg caaggtaatg tggttctgct ggcgctggat gaagtgaaac
    72181 aaggttcaat gccggaagat cagaaaaaag cgatggtgca gggtatcacc cagaacaacg
    72241 cacaaatcgt ctttgaagct ctgatgagta acctgcgtaa agaggcgaaa atcaaaattg
    72301 gcgatgcgct ggaacagcaa taatcctgaa gccgcctcgc aaaaaaatgc tttgcagctg
    72361 taacaagaaa aggtcgcttt cgcggccttt tccatttctg aacattgcca tttgtttact
    72421 gttttcactg ccgttaaggt gattccactg ttaacaaaca aggagaaaac agtatgaaac
    72481 acggaattaa agcactgctc attaccctgt ccctggcctg tgccggaatg tctcatagtg
    72541 ctctggcggc agctcctgcg gcaaaaccga caacggtaga aaccaaagcg gaagctcctg
    72601 cagcacaaag taaagcagca gtaccggcga aagccagtga cgaagaaggc acccgggtca
    72661 gcattaataa tgccagcgcg gaagagttag cccgcgcgat gaatggcgtt ggcctgaaga
    72721 aagcgcaggc gattgtcagt tatcgcgaag agtacggtcc gtttaaaacg gtggaggatc
    72781 taaagcaggt gccggggatg ggcaattcgc tggtggaacg taatatggcg gtattaaccc
    72841 tgtaattaat ttgcatagtg gcaatttttt gccagactga agaggtcata ccagttatga
    72901 cctctgtact tataacagtt cttataacag ttcttataac aacaacgtaa ggttattgcg
    72961 ctatgcaaac acaaatcaaa gttcgtggat atcatctcga cgtttaccag cacgtaaaca
    73021 acgcccgcta ccttgaattt ctcgaagaag cccgctggca tgggttggaa aatagcgaca
    73081 gttttcactg gatgacggcc cataacatcg ctttcgtcgt ggtcaatatc aatattaact
    73141 atcgccgccc ggcggtatta agcgacctgt taaccattac cagtcagttg cagcaattaa
    73201 acggtaaaag tggcatctta agccaggtca ttacactgga gccggaagga caggtggtag
    73261 cggatgcgct tattacgttt gtttgtattg atcttaaaac gcagaaagca ttagctctgg
    73321 aaggggaatt gcgcgaaaag ctggagcaga tggttaagta aacgttttgt ggtgccggat
    73381 gctcaagccg catccggcga cacccggaat aattacttca acccggtttt ctgcttcatc
    73441 gctgccatca ccgtcggttt atcggccaga taatgattca aaccgttggc acgtaaatta
    73501 cacgccgcac aatgaccgca accgtcgcct ttaatgccgt tataacaggt cagcgtttcg
    73561 ttacggacta aatccagctt gccgtaataa tctgccagcg cccaggtttc cgctttatca
    73621 atccacatca gcggcgtttc aaaacgaata tctttcgcca tgcccaaact gacggcatgg
    73681 tttagtgctt tcacaaactc atcgcgacaa tccgggtagc cggagaaatc cgtttcgcag
    73741 acgccggtaa ttacggcttc tgcttttacc tgatacgcat atattgccgc cagcgtcagg
    73801 aacaaaatat tacgccctgg gacaaacgta ttcgggatac catcggcttc aggttcataa
    73861 tcaggcaccg gaatgctgtc acgcgtcagg ctgctgaccg ccagctcgtt gagcagcgtt
    73921 acatcaagaa ccttatgcgc gcgtgccccc agtttcagcg ccagttcgcg tgccacgtcg
    73981 atttctgcgc gatggcgttg accgtaatcg aacgtcacgc aatggacttc atcatattgt
    74041 tgtaatgcct gcaccagaca ggtggtggaa tcctggcctc cactgaacac aacgacagca
    74101 cgtttcatag ataatcctgc ttgaacaata aaagcgttat ggtaacgcct gcgattaacc
    74161 cggaccagct attcattgcg acggcgcggg aagccaggct tcggtaaatt caaaccagcc
    74221 gcgcggtgtc agtcgcacac cgttcacgcc gggaggggcg ctaatgcgat agtgatagtt
    74281 gaacagcggc gtcagcgtcg catctgccat taactggcta aaaaccgctt tcagggcatt
    74341 aaatcggttt tcctcatcag gcattacttg cactgcgtcc agtgtcgatt gcaaatgtgc
    74401 atatgctgga gcgtcgaaaa catgtggcca cagtggatcg caacgcagcc attgctccag
    74461 ggtatattcc ggtgcttcgc caattaatct gtcgcccatc atgaggtctg cgtgtgccag
    74521 tagggtcgtg tcgtcccagt tttttgcgtt atgaaaaata attgtgagtt cacagccttc
    74581 cgctgccagt gtcgcctgta ggcgttctgc catggtatga agttctatcg gtaggtgata
    74641 aaccagcgtc aaggttttcg gtagtttaac ttcatccggt acctgccaat gcggaatagt
    74701 ccagccaggc agtaatgcat gactggcggt gatcaggttt tctccgactt ctaacgtttg
    74761 taataaaccg gattgatgaa taatggagat tacttttcgc gcctgccaga gggacagtcg
    74821 gagacttttg cgcaatgtta aatagcaaaa acctaaactg atgccgctac tgacctggct
    74881 gacccgttgc agctcctccg gtttgccaat ggtgatttgc acgggatgcc gacaactggt
    74941 tcccaaatct ttttcgaaaa gcggcggagt tatccagtac tcaaccgctt taagcagcgg
    75001 atgacgtaaa tggtaataat catggctctc caggcgcacc agttccgctg tgaattgtgt
    75061 taagcgaaaa ggacctgtgc cgatcagtgg gaattgcgga tgcgccagat ggctgcaata
    75121 gctcgccagt cggtgcgcaa gccagtaatc ggggcgatgt aaaaagaagg tcagacactg
    75181 cggatgggtg acttcaatac gcttcacgct aataaataat tgatccagtg ctggcagttg
    75241 taacagcatc aataatcgct ggtgtaagtg tgaggctttt actgcatcgc cgttatgcca
    75301 gtgtagcgtt gaacgaagat aaaagtccca gcgtaacccg tcagtagagg tttcccagtg
    75361 atgtgctaaa tcgccaatcg ggcgctgagt attattatcg aagcgggtca ggccggaaaa
    75421 tatctgcccg gccagatgct gctcggcacg gccgggcaaa aagcccggtt gtagcggttc
    75481 gagcgggcga tagtagggaa tacgcaacgt gggcgtatcg ttttgccatt gtccgcccat
    75541 aaacggctgt aacagagtgc gcagctcacc tggggccagt tgcgccagct ccagcacatc
    75601 ttgctgcttt ccggtttcca gcgcctgttc catcatcgca ttgcgtagcg attctggcgt
    75661 gaccagaaag cgtagttgac cgcgctttcc gcgtcctgac tgcgcctgcc actccagcca
    75721 tcccgcctcc tgtgcctgac gcaacaccgt acgaacatgg cgttcgctgc aaaaacagcg
    75781 ttcggccagt tcgctgacgg tgacggtttg cggctttccg gcggaaggtt gccacagacg
    75841 ttgatactgg ttaagacggt tgagcagtcg catataaacc cggaacaata ttatttaact
    75901 attcactatt acttccgtat atatcaggtg atactcaatc accattaact gtgtcacaga
    75961 gtggagaaag aaatggctcg tctggcagca tttgatatgg atggcacttt attgatgcct
    76021 gaccatcatt taggtgagaa aaccctctct actttggcgc ggctgcgtga acgcgacatt
    76081 accctcactt ttgccacggg gcgtcatgcg ctggagatgc agcatattct cggggcgcta
    76141 tcgctggatg catatttgat tactggcaac ggaacgcgcg tgcattctct ggaaggtgaa
    76201 cttttacatc gtgatgattt acctgcggat gtcgcggagc tggtgctgta tcagcaatgg
    76261 gatacccgag caagcatgca tatcttcaat gacgatggtt ggtttaccgg gaaagagatc
    76321 cctgcgttgt tgcaggcatt tgtctatagc ggttttcgtt atcagataat cgatgtcaaa
    76381 aaaatgccac tcggcagcgt caccaagatc tgcttctgtg gcgatcacga cgatcttaca
    76441 cgcttgcaga tccagctata cgaagcatta ggcgagcgtg cacatttatg tttttccgcc
    76501 acggattgcc tcgaagtgct gccggtgggc tgcaataaag gcgctgcatt gacggtgctg
    76561 acccaacatt taggtttatc gttacgcgat tgtatggcct ttggtgatgc gatgaacgat
    76621 cgcgaaatgt taggcagcgt cggtagcgga tttattatgg gcaatgcgat gccgcaactg
    76681 cgcgcggagc tcccgcattt accggtgatt ggacattgcc gaaatcaggc tgtctctcac
    76741 tatttgacgc actggctgga ctatccacat ctaccttatt cccccgaata acgagatccc
    76801 ttccagcacc gggcaattgc ccggtttttt ttgcgttgaa tttgtcattt tgtgccgtgg
    76861 tgcttaaacc gcacagaata aattgtcgcg atttcacctt taaaatagaa ttaaaagaga
    76921 aaaaaattct ctgtggaagg gctatgttag ataaaattga ccgtaagctg ctggccttgc
    76981 tacagcagga ttgcaccctc tctttgcagg cactggctga agccgttaat ctgacaacca
    77041 ccccctgctg gaagcgtctg aaacggctgg aggacgacgg tattcttatc ggcaaagtcg
    77101 ccctgctgga tccggaaaaa ataggcctcg gcctgaccgc ctttgtgctg ataaaaacgc
    77161 aacatcacag cagcgaatgg tattgccgct ttgtcacggt ggttaccgaa atgccagaag
    77221 tgctggggtt ctggcgcatg gctggtgaat acgattatct gatgcgcgtc caggttgccg
    77281 acatgaaacg ctacgacgag ttttataagc gtctggtaaa cagtgtaccg gggctgtcgg
    77341 acgtcacttc cagcttcgcg atggaacaga ttaaatacac cacttcttta cccatcgaat
    77401 aaatatccag aatcaagtca ggacacaacg cgtgcgatta tttgctcaat taagctggta
    77461 tttccgtcgg gaatggcgtc gctatctcgg ggctgtcgcc ttgcttgtca ttatcgcgat
    77521 gctgcaactg gttccgccaa aagtggttgg tattgttgtt gatggcgtga cagaacaaca
    77581 ctttactacc gggcagatcc tgatgtggat cgccaccatg gtgctgattg ccgttgtggt
    77641 ttatctcctg cgttacgtct ggcgcgtatt gctgtttggt gcgtcttatc aactggctgt
    77701 tgaactgcgt gaagattatt accgccagct aagccggcag catcctgagt tttacctgcg
    77761 tcatcgcacg ggcgacctta tggcccgtgc gacaaatgac gtcgatcgcg tcgtgtttgc
    77821 cgccggagaa ggggtgctga cgctggtgga ttcactggta atgggctgcg ctgtgttgat
    77881 tatgatgtct acgcaaatta gctggcagtt gaccttattt gccctgttgc cgatgccagt
    77941 gatggcgatc atgatcaagc gcaacggcga tgccttgcat gaacgcttta agctggcaca
    78001 ggcggcgttt tccagtctta atgaccgcac ccaggaaagc ctcaccagta tccgcatgat
    78061 caaagccttt ggtctggaag atcgtcagtc ggcgttattt gccgcggatg ccgaagatac
    78121 cggcaaaaaa aacatgcggg tggcgcgtat tgatgctcgt ttcgacccga ccatctatat
    78181 cgcgattggt atggcgaact tgctggcgat cggcggcggt agttggatgg tggtgcaggg
    78241 cagtttaacg ctgggccagc tcaccagttt tatgatgtat ttaggtctga tgatttggcc
    78301 aatgctggcg ctggcatgga tgtttaacat tgtggaacgt ggcagcgcgg cgtatagccg
    78361 aattcgtacc atgctggccg aagcgccagt cgttattgat ggtagtgata aggtgccaga
    78421 aggtcgtggt gaactggatg tgaatattcg ccagtttacg tatccgcaga ctgaccatcc
    78481 tgcgctggaa aacgtcaatt tcgccctgaa acccggtcag atgctgggta tctgcgggcc
    78541 gactggttcc ggcaaaagta ccctgttgtc gctcattcag cgtcatttcg acgtcagcga
    78601 gggtgatatc cgttttcatg atattcctct gacgaagtta caactcgata gctggcgtag
    78661 ccgtctggcg gtggtcagcc agacaccatt ccttttttcc gacaccgtgg cgaacaacat
    78721 cgcgttgggt tgcccgaatg ccacccagca agagattgaa cacgtagcgc ggttagccag
    78781 cgtacatgac gatattttgc gtctgccgca aggttacgac acagaagtgg gcgagcgcgg
    78841 tgtgatgctt tctggcggac aaaaacagcg tatctccatt gctcgagcgt tattagtcaa
    78901 cgcggaaatc ctcatccttg atgatgcgct ttcagcggtg gacggacgca cagagcacca
    78961 gatcctgcat aacctgcgtc agtgggggca gggaagaacg gtaatcatca gtgcccatcg
    79021 cctttctgca ctgacggaag ccagtgaaat tattgtgatg cagcacgggc atatcgccca
    79081 gcgtggcaat catgatgtgc tggtacaaca aagcggctgg tatcgcgata tgtatcgcta
    79141 tcaacaactg gaggcggcgc tcgacgacgc cccggaaatt cgcgaggagg ccgtcgatgc
    79201 gtagttttag ccaactgtgg ccgactctca agcgtctgtt agcgtacggt tcaccgtggc
    79261 gtaaaccgtt ggggattgcg gtcctgatga tgtgggttgc ggcggcggca gaagtcagtg
    79321 ggccgctgct tatcagctat tttatcgaca atatggtagc gaaaaataac ctgccgttga
    79381 aagtggttgc agggctggcg gcggcgtatg ttgggctgca actgtttgca gccgggctac
    79441 attacgcgca gtcgctgctg tttaatcggg cggcagtagg cgtagtgcaa cagttgcgta
    79501 ccgacgtgat ggatgctgcg ttacgccagc cattaagcga gtttgatacc caacccgtcg
    79561 ggcaggtgat ttcccgcgtc actaatgaca ctgaagtgat ccgcgatctc tacgttaccg
    79621 tagtggcaac tgtcctgcgt agcgccgcac tggtgggcgc gatgctggtg gcgatgttca
    79681 gcctcgactg gcgaatggcg ctggtggcga taatgatttt cccggtggtg ctggtggtaa
    79741 tggtgatata tcagcgttac agcacgccga ttgtccgtcg tgtgcgcgct tatctggcgg
    79801 atatcaacga cggctttaac gaaatcatca atggcatgag cgttatccag cagttccgtc
    79861 agcaggcgcg atttggcgaa cgtatgggtg aggccagtcg ttcacactat atggcgagga
    79921 tgcaaaccct gcgcctcgac ggttttctgc tgcgtccgct gctgagtctg ttttcatcgc
    79981 tcattctttg tggcttgttg atgctgtttg gcttctccgc cagcggcacc attgaagtgg
    80041 gcgtgttgta tgcgttcatc agttatttgg ggcgacttaa cgaaccctta atcgaactga
    80101 ccacgcagca ggcgatgctg caacaggctg ttgttgctgg tgagcgcgtt tttgagctga
    80161 tggacggacc gcgccagcaa tatggcaatg atgatcgctc gttgcagagc ggcaccatcg
    80221 acgtcgataa cgtgtcattt gcttatcgcg atgacaatct ggtgctaaag aacattaatc
    80281 tctctgtgcc ttcgcgcaac tttgtggcgc tggtcgggca taccggcagt ggcaaaagca
    80341 ccctcgccag tttattgatg ggctattacc cgctaacgga aggtgagatt cgccttgatg
    80401 gtcgtccatt aagtacgcta agtcacagcg cgctgcgcca gggcgtggca atggtgcagc
    80461 aagatccggt ggtgctggcg gataccttcc tcgccaacgt gacgctggga cgtgatatct
    80521 ctgaagaacg cgtctggcag gcgctggaaa ccgtgcagct ggcggagctg gcgcgtagca
    80581 tgagtgatgg tatttacacg ctgcttggcg agcaggggaa taatctctca gtcgggcaaa
    80641 agcaactgct ggcactggcg cgcgtgctgg tggagacgcc gcaaatcctg atccttgatg
    80701 aggcaaccgc cagcattgac tccgggactg aacaggcgat tcaacatgct ctggcggcgg
    80761 tgcgtgaaca tactacgctt gtggtgattg ctcaccgctt atcgactatt gttgatgccg
    80821 acaccattct ggtgcttcat cgtgggcaag ccgtggagca gggcactcac cagcaactgc
    80881 tggcggccca gggacgatac tggcagatgt atcaactgca acttgcgggc gaagagctgg
    80941 cagccagcgt gcgtgaagag gaatcattga gcgcctgaat agcgcaatat ttcatcgttg
    81001 gtgcaaaaat gtaacgcact gtgcactgtc atagtgcgtt ttcattttca atcttcttaa
    81061 cttcctgctc tctttctcgt ttttcatttc tggcacaccg cttgcaatac cttcttcgtg
    81121 tagcagaacc attaccgaat tctgaccgga ggggatctat gaagctggtg accgtgataa
    81181 tcaaaccatt caagctggaa gacgttcgtg aagcgttatc ttccattggt attcagggcc
    81241 tgaccgtcac cgaagtgaaa ggttttgggc gtcagaaagg gcatgccgag ctgtaccggg
    81301 gggcggaata cagcgtcaac ttcctgccaa aagtaaaaat tgatgtggcg attgctgatg
    81361 accaactcga tgaagtgatc gatatcgtca gcaaagcggc ttacaccgga aaaattggcg
    81421 acggcaaaat cttcgtcgct gaattgcaac gcgtcattcg tattcgtacc ggcgaagccg
    81481 acgaagcggc gctgtaatct ctggcacaca gcaacaggaa cgaaaaatga agatagcaac
    81541 gataaaaact gggcttactt cactggcgat gctgccggga ctggtaatgg ctgcacctgc
    81601 ggtggccgat aaagccgaca atgcatttat gatgatttgt actgcgctgg tgctgtttat
    81661 gactattccg gggattgccc tgttttatgg agggctgatt cgtggcaaaa acgtgctgtc
    81721 gatgctgacg caggtgaccg tgacgtttgc actggtctgt attctctggg tggtttacgg
    81781 ctactcgctg gcgtttggcg aaggcaacaa cttcttcggc aacattaacg ggttgatgct
    81841 gaaaaacatt gaactgacgg cggtgatggg cagcatttat cagtatatcc acgtggcgtt
    81901 tcagggatcg tttgcctgca ttaccgtagg cttgatagtt ggggcgctgg cggaacgaat
    81961 ccgcttctca gctgtgttga tttttgtggt ggtatggctg acgctctctt acattccgat
    82021 tgcgcatatg gtctggggcg gcggtttgct ggcttctcac ggtgcgctgg atttcgcggg
    82081 tggcacggta gtgcacatta acgccgcaat cgccggtctg gtgggcgcgt atctgatagg
    82141 caaacgcgtg ggcttcggca aagaggcgtt taaaccgcac aacctgccga tggtcttcac
    82201 cgggactgcc attctctata tcggttggtt tggctttaac gccgggtcag cgggcacggc
    82261 gaatgaaatc gcggcactgg catttgtgaa tactgtggtc gcaaccgcgg cggcaattct
    82321 tggctggatc ttcggtgaat gggcgctgcg tggtaagcct tcactgctgg gagcgtgttc
    82381 tggcgcgatt gccggtctgg tcggcgtgac gccagcctgt ggttacattg gggttggcgg
    82441 cgcgttgatt atcggcgtgg tagctggtct ggcgggcttg tggggcgtta ccatgctcaa
    82501 acgcttgctg cgggtggatg atccctgcga tgtcttcggt gtgcacggcg tttgtggtat
    82561 tgtcggctgt atcatgaccg ggatttttgc cgccagctcg ctgggcggcg tgggcttcgc
    82621 tgaaggtgtg acgatgggcc atcagttgct ggtacagctg gaaagcatcg ccattacgat
    82681 tgtctggtct ggtgtggtgg catttatcgg ctacaaactg gcggatctga cggttggtct
    82741 gcgtgtaccg gaagagcagg agcgagaagg gctggacgtc aacagccacg gcgagaatgc
    82801 ctataacgcg taacaagcac tgcaaaaaac agccggacgg ttttcacctc cggctatttt
    82861 tttaattgtg attacgcatc accccttcct gaacggtcga ggcaaccagc acgccgtcct
    82921 gggtataaaa ctcaccgcgc acaaagccgc gtgcgctgga cgccgaggtg ctttccacgc
    82981 tatacagcag ccattcattc aaattaaacg ggcgatggaa ccacatggaa tggtcaatgg
    83041 tggcaatctg aatccccggt tcgagaaaac cgatgccgtg cggctgtaga gctaccggca
    83101 ggaaattaag atcagaagca taaccgagca gatactgatg aacgcgcaga tcatccggca
    83161 cgctaccatt tgcgcggatc cacacctgac gatgcggttc tgcgacgtga cctttcagtg
    83221 ggttatgaaa ctccaccgga cggacttcca gcggacgatc gcagatgaat ttatctttca
    83281 gcactggcgg cagcaggtgc gccagcgatt gggcgatttg cgtttctgaa ggcaggccat
    83341 caggcgctgg tgcggacggc attgtttttt gatgttcgaa acccgcttct ggtgcctgga
    83401 aagaggcagt catataaaaa atcggtttgc cgttttgaat agcagcaacc cggcgggcgc
    83461 tgaagctgtt accgtcacgc agtgtttcga catcataaat aatcggcttc ttactatcgc
    83521 cagggcgaag aaagtagctg tgaaaagaat gtaccagccg ctcgtcaggg acggtctctt
    83581 ttgcagcata caaggcctga cccacgacct ggccgccaaa tacctggcgt aaacctaaat
    83641 cttcactctg gccgcgaaag agtccttcct caattttttc cagatttaac aatgtcagta
    83701 aattttttag cgcctgactc atataactct ccagtaacaa agctgccgca gcaagccaaa
    83761 gtgagttgag tataacgcaa atttgccact ggtccgatgg gtgcaatggt ctgaattacg
    83821 ggctaattac aggcagaaat gcgtgatgtg tgccacactt gttgacgtta ctattttgtt
    83881 aaccactctt ccggcgagga aagttagccc gctggtgcat tgataataag gagaagtgaa
    83941 tgaaactcgt gcacatggcc agtggtttag cggttgcgat tgcgttggcg gcttgcgcag
    84001 ataaaagcgc ggatattcag acgccagcac cggctgcaaa tacgtctatt tcagcaacac
    84061 aacaacctgc tatccagcaa ccgaatgtct ccggtaccgt ttggatccgt cagaaagtcg
    84121 cactgccgcc tgatgccgtg ctgaccgtga cactttctga cgcgtcgtta gccgatgcgc
    84181 cgtcgaaagt gctggcgcag aaagcggtgc gtaccgaagg taaacagtca ccattcagct
    84241 ttgttctgcc atttaacccg gcagatgttc agccgaacgc gcgtattctg ttgagtgcgg
    84301 cgattaccgt gaatgacaaa ctggtattta ttaccgatac cgttcagccg gtgatcaacc
    84361 agggcggaac taaagccgac ctgacattgg tgccggtgca gcaaaccgcc gtgccggttc
    84421 aggctagcgg tggcgcaacg actaccgtac cttcaacttc accaacccag gtgaatccgt
    84481 cttcggcagt tccagctcca acgcaatatt aagcgaagtt aaccctctcc gcccggagag
    84541 ggttagtagt tccagcgata aagctgcaag tcgatttgcc cgcttcccga caccatcaca
    84601 ccttctgcca gtaatgcctg tcgctgacgc tgtaaatccg gtccggtcag tgaaatggtg
    84661 ccgtggcgat taaccacccg gtgccagggc aaggtgctgc cttcggggag acgctttaac
    84721 acaccgccaa cctggcgcgc ggcacggggc gagcccgcca gtttcgccac atcaccgtaa
    84781 gtggtgacat agccttcggg aatagcggct acgatttgcc agacgcgttg gggaaatgaa
    84841 tcttcttttt ccatcttttc ttcctgaggt aatttttcag cataatctgg aaaaacgccc
    84901 gagtgaagcc gcattgcgca agaaaccagc atctggcacg caatgggttg caattagccg
    84961 gggcagcagt gataatgcgc ctgcgcgttg gttctcaacg ctctcaatgg gggctctgtt
    85021 ggttctcccg caacgctact ctgtttacca ggtcaggtcc ggaaggaagc agccaaggca
    85081 gatgacgcgt gtgccgggat gtagctggca gggcccccac ccatttctgc ctcctaccat
    85141 ttcgtcaaaa aatcccaaca tggctaaact ttaaccacaa ctgacgtcgc aagaattgtc
    85201 tggctgcgca gtacgcttcg gaggtatgtc tgatgaagta tgttgatggt tttgttgttg
    85261 ccgttcctgc cgataaaaag gatgcctatc gggaaatggc cgctaaggcc gcgccattat
    85321 ttaaagagtt cggggcgctt cgtattgtcg aatgctgggc cagcgatata ccggatggta
    85381 aagtgaccga ttttcgtatg gcggtgaaag cggaagagaa tgaagaggtt gtctttagct
    85441 ggattgaata cccttcaaaa gaggtccgcg acgctgctaa tcaaaagatg atgtcggacc
    85501 cacggatgaa agagttcggc gagtccatgc cgtttgatgg taagcgaatg atctatggcg
    85561 gattcgagtc aatcatcgac gagtaggtag cgtgacgggc tgtgcggcgt gccgtcagcc
    85621 ctataattca caaatgttgc tcggcccagc gtaagaaatc ctctttcggt aatgccttgc
    85681 tgtagagcca gccctgaccg tagtgcacgc catgctggcg tagccactct tcttgtttac
    85741 tggtttcgat tccctccgca accattttca gtttcagtgt ttttgccatt tcgatgatat
    85801 gtggcgtgac attcttatat tccagcgcat caacgaaaga tttatcgatc ttcagaatgt
    85861 cgacatccag atcctgtaaa tagcttaaac ttgaataccc tgtaccaaaa tcatcgagat
    85921 aaatttcatg gcccgcctcc cggtagcgag aaattatcgg ggcgctggtt ttcggatcgg
    85981 caaactcgcg ttcagtgagt tcaagcgcga tctgtctggg attaacctga tagtgattga
    86041 tcatttcacg cagcaattgc gggatttttt ccgaggtgag cacggtggat tcaagattga
    86101 tcgaaatatg ctgctgagga tgctgacgca gccagtcgcc catatcttca aagacgcttc
    86161 ttataatcag tagcgtcaat ggctcagaaa ggcccgtttg ctgtgccagc ggaataaaac
    86221 tatctggtga caaccaacta ccgtctgtct gcggccagcg cgccagtgcc tcagcaccga
    86281 caattttgcc attggctaag gagacaatcg gctgatagtg cacgcaaata tcacgatttt
    86341 cgatagcatc ctgcagccga tgatgcggtg actggatacg gcgcaaaata cgcagcacaa
    86401 acatcgctgc cagcaggcca atcaccaacc cgagcggtaa ccaaataaag acttgccgat
    86461 accagccttt ctgcaacatt ttcgttgaag cccaggtgat gatcgaaata ttcatctccg
    86521 gtaagggcag gatatcgtaa atgattccat tattttcgat atgctcaccg ggtgtttttt
    86581 gtagcctggt aataattccc tgagcaagtt catcgctgct ggttatgaca acgttatggg
    86641 cattgccaat aatggcggca tcaatttgcc atgagctata gggaatgaca tcaataaagg
    86701 aagcggggtc gatcatgacg acataatgtg ccgttcccat ggcgaccatg taacggataa
    86761 tgcctaaatc gttatgcgat gttaaccaga cacgataacc atctttcgaa attttacctg
    86821 gctcggggaa ggtatcgggc gggctttcat gctccagaga cgaacattgg ggaacgttgt
    86881 tatcgatata aaccacttcc tgaatatagc gataactgta agatacccga cgcatttcca
    86941 tgagatgggc ttcgctacag gcagcgcctt gccatctttc cagctcttgc agcgcatctt
    87001 tcccttgtgt cgccacctta ttggcccgaa tagcgacgcg ggaggaatac gtattcagct
    87061 cttcaataaa tgacgtttct acctgctgat gggccagcca gatgcttaag ccgacaggca
    87121 gcaatactga aagaatcagt actcccgaaa taaggccgac cagatgtcgt gttctcacca
    87181 gcatatcctt attaacacag tgtagggaaa gtatatctga ttgtggaaaa aggctggcag
    87241 gagataagga ggtagagctg gtatttcatg aagtgatggg tggaagcaat cgttgtcatt
    87301 tgaccaggcg tagagcttta cgcctggtat gtacccctaa cttaagatgt tgattcggct
    87361 cgagcgaggg taaaaatatc gtaaaaagat agttcacctt tacggacgat cattttttgc
    87421 agttgttctt tatgaacatc cgcgacacgt ggagagttca ggatggcttc aaccagcgcg
    87481 gcaggtacaa agcgcgtgtt gtaccattcg ccgttatagc aaacgcggaa atccagcacg
    87541 tcgatatctt catagcggta gcgtgggtag acatcgaaaa agaagaaacc attaagcagg
    87601 ataaataata caaccagtag ccagacagag cctgaaagcg tttcggattg caacatcacc
    87661 gccagggtag caaaaaaagc aacgtacata ccgataaaca gccccggatg tttacggata
    87721 aaactgatac taaagcgggg tttgttgtcg cgtttttcgc gggtattcag agactcaatc
    87781 gtttcggtca gcaggcgttg tatttcggtc atcgtttgcc ttcgtgatat ctgcaacttt
    87841 ccagggaaca ccctatttta acgtgggaat agtagagggg aagtaacaga tttgccacga
    87901 ttttgcataa cagttgagaa aagctggtta caatttttta atgattctgg ctggattacc
    87961 gcccacgaca acgttgtccg ggacatcttt tgtgacaact gcacctgagg ctaccacgac
    88021 gttatcacca atggtcacac cagggttaat gactgcacgt ccgccaatcc agacgttatt
    88081 accgatggtg acgggtttcc ccagttcagc accgctatta cgtgctacag ggtcgatggg
    88141 atgtgttgcc gtgtagatat gaacgcctgg tgccaacata cagttatcac caatgcgaat
    88201 agggcagaca tcaagcatca cgcaatcgaa gttggcgaaa aaattattgc cgagaaaaat
    88261 gttatagcca tagtcacagc gaaacgttgg ctcaatataa gcctctgtca cctgaccgaa
    88321 taaatcagca agaatttgct ggcgtaatgt gtgctcttcc gccagggaat gattgtatcg
    88381 gtgaataagc cgacgagcgc gcaggcgatc gcgagataac gcctcatctg ccgagtgata
    88441 caactcacca gcaatcatct tttctttttc tgtgctcatt actgacttcc ggttgctgaa
    88501 aatgcggcaa cacagtaaga cgaaaagtca gtgaagagaa cgttcccatt acatctgtgt
    88561 gatgaagatc acatagggta tgccttcatg gcgaaaaaaa gtataaaatt cttaataaac
    88621 agccggttat agctccgaaa gcgagttatt tattagcgaa taaatttcca tactgaggaa
    88681 gggatcttgt cgtacagttt attcatggtc aattcggcga ggcggtgatc tgcggctgag
    88741 taaaataccg ccagttcatt atctgataat tcgtatttat ttttctcgat aacacgctcc
    88801 agcgtgtcaa ttgtctggca acgacgtaaa cgcattaaat aatcggtttt cgttaaaggt
    88861 ttttcggaca tacttctacc catggttgta ataattctaa caagataaac tcgcaggatt
    88921 ctctttcgtc gcattgacaa aacaacggaa tagtcgatta cctgacttcc gccatttctg
    88981 aagatcctgc atattaatac cataactact gaacaacata aaggtgtcat ccagatattc
    89041 gtcgatctgc tcaatgagct tattgtcttc attatactta attttgtaat taagtgcgaa
    89101 ggtcgcaata tgctcaatca gttcattcaa ctggaggttg atcgccgagg ttgggtcgtt
    89161 aacccagcca tgattgcttt cttcaaggtt tgcaaggcag tcatgataca gggtttcaca
    89221 gagaaactta agctgtgcga tatcatgtct tttgggtgag tattcatcca taacgcgtcc
    89281 ccttcttagc ggttgaacta acggacacct ttcgggatgg aaaaaactta ctgacctgga
    89341 cttgccctct cgtttgttag cttaactata agccactctt tgcaggtttt catcgcatta
    89401 ttacgaaaaa ttacaattag gaaggaagcg ggacaggact cactttttca tactagcacc
    89461 aacccgcagc aggtaaaagc agtttgctcg aactgttcat aacatttcag aattatcgcc
    89521 agaagaaatt ggtgacacta ataccaggat tgctctgaat atgacgtaat aaccgaggaa
    89581 tgaataaaga attaccgcaa ataattaaga atagcctcta aatggttatg gattattaaa
    89641 tctattagcg ctacttaata taaattaact aacaatcagt attttttatg aattttatac
    89701 gtggttaata ctggttttcg tatgggatcc tgagttggtg gttcaataca tccttaatgt
    89761 tcgtaggtta tgcataaaaa aggccgcttg cgcggcctta gtgattacac gttgtatcaa
    89821 tgatgatcga cagtatggtt gtgctcgata tcttcattct tgcggctaaa gcggcggcga
    89881 accaccacaa agaataccgg aacgaagaag attgccagta ccgttgcggt caccatcccg
    89941 cccattacac cggtacctac tgcgttctgc gcgccggaac cagcaccagt actgataacc
    90001 agcggcataa cgccgaggat aaacgccaac gaggtcatca ggattgggcg taaacgcatc
    90061 cgcaccgcat caagcgtcgc ttcaatcaga cctttacctt ctttatccat caagtctttg
    90121 gcgaattcga cgataagtat cgcgttcttc gccgacaaac caatggttgt gagcaggcct
    90181 acctggaagt aaacgtcatt ggtcaggcca cggaaggtgg cagccagcaa cgcaccgata
    90241 acccccagcg gaacgaccag cataacggag aacggaatcg accagctctc gtacagcgca
    90301 gccagacaca ggaacacgac aatcaacgaa atcgcgtaca gtgaaggtgc ctggttgccg
    90361 gagagacgtt cctgatagga catccccgtc cagtcatagc caacaccggt aggcagtttg
    90421 ctcgccagtt gttccatcag ctccattgct tcaccggtac ttttacccgg tgccgcctgg
    90481 cctaagattt ccatagatgg caggccgttg taacgttcca gacgcggcga accgtactcc
    90541 caacgagaag aggagaacgc cgagaacggc accatctgac catcagcagc acgaacatac
    90601 cagtcgccga tatcatccgg cagcatacgg tatttcgcct ctgacatgac gtaaactttc
    90661 ttcacacgac cgcggtcgat aaagtcgttc acatagctac cgccccatgc agcgcccaga
    90721 gtggtgttaa tgtcgttgat agaaacaccc agcgcctgcg ctttttcctg gtcgatatca
    90781 atcttaaact gcggggtatc ttccagaccg tttggacgta cgctggtcaa catatcaggg
    90841 tgcttcgctg cttctgcaag caactggtta cgcgcctgag tcagtttttc gtgaccaagg
    90901 ccagcctggt caatcagctc aaagtcaaag ccggttgcgg tacccagttc cacgattgcg
    90961 ggcaggttaa aggcgaaaac catcgcatct ttgatttgcg agaaagcacg tgttgcacgc
    91021 atggtaatcg cttcaacttt gttttcttcg cccggacgat cggcccagtc cttcaaggaa
    91081 acgaacgcaa taccggtatt ctgaccacgt cccgcaaagc cgaagccgtt aacggcgaac
    91141 accgactcaa cgttgttctt ttctttggtc agatagtaat tcgttacctc attgagcact
    91201 ttctgcgtac gttcctgcgt tgcacctgct ggcagctgaa ccatggtcat aaatacgccc
    91261 tggtcctcat ctggcaagaa ggagcttggc agacgcacga acagataggc catgccgacc
    91321 acgatgatca gatacagcac caggtaacgc cccgtactgc gtagaatacc gcctacgctg
    91381 tcggtgtagt ggtgcgtgct cttctcgaac atgcggttaa accagccgaa gaagcctttt
    91441 ttaccttccc cgtgatcgcc tttggcaatc ggtttcagca tggtggcaca aagagccgga
    91501 gtcaggatca acgccaccag taccgacagc gccattgctg aaacaatggt aatagagaac
    91561 tgacgataga tagcaccagt agaaccgcca aagaaggcca tcggtacgaa taccgccgac
    91621 agtaccatcg cgataccgac cagagcgccc tgaatctgcc ccatcgactt acgggtggct
    91681 tcttttggtg gcaaaccttc ttccgccatc acacgctcaa cgttttctac cacaacgatg
    91741 gcgtcatcca ccaacaggcc gatggcgagc accatcccga acattgttag cgtgtttatc
    91801 gagaagccaa aggcggcaag gacggcaaag gtcccgagca ataccaccgg tacggcaatg
    91861 gtcggaatca acgtcgcgcg gaagttctgc aagaacagat acattaccag gaacacgagg
    91921 atgatcgctt cgaccagcgt tttaaccact tcgtgaatag agattttcac gaacggtgtg
    91981 gtgtcatacg ggtaaacaat tttcagaccc gacgggaaga acggttccat cttcgccagt
    92041 tcagcacgga ttgccgcagc ggtatccagc gcgttcgcac cggtcgccag cttgatcccc
    92101 agaccggaag ccggttggcc gttaaactct gcgatgatgt cgtagttctc accacccagc
    92161 tcaattttcg ccacatcacg cagcagcacg cgggaaccat cctgattcac tttcagcagg
    92221 attttgccga actcttcagt agaggtcaga cgcgtctgag caataataga ggcgttaagc
    92281 tgttggcctt tcaccggcgg cgtaccaccg agctgaccag ctgcaacctg ggcgttctgt
    92341 gctttgatgg cggtaatgac atcaaccggc gttagctgga atttgttcag ttcattcggg
    92401 ttcatccaga tacgcatcgc gtactgtgaa ccgaacaact gaacgtcacc cacgcccgac
    92461 gtacggctga tggcatcttt catattcgcc gccacgtagt cggagatatc ctcctgcgtc
    92521 atggtgccat cggtgttgat aacgccgaca accatcagga agctgctgga tgatttctca
    92581 acgctcaccc cttgctgctg tacttcttgc ggcagcaacg gcatcgccag ctgcagtttg
    92641 ttctgcacct gaacctgcgc gatatccgca tcagtaccag actcaaaggt cagggtgatc
    92701 tgcacggtac ccgtggagtc actgttagag gacatgtaca tcaggttatc gataccgttc
    92761 atattctgtt cgataacctg tgtcaccgtg tcctgcactg ttttcgcatc agcgccaggg
    92821 taggaggcgg agatcgttac tgccggcggt gcaatcgtag gatattgcgc caccggcagt
    92881 ttgaggatcg ccagcccccc tgccaacatg atgataatgg cgatcaccca cgcaaaaatt
    92941 gggcgatcga taaagaaatt aggcatgtct taacggctcc tgtttaagtt aagacttgga
    93001 ctgttcaggc tgagcaccgc ttgcggcttg ctggttatta tcagcggtaa cttcttgtgc
    93061 ttttacctgg acaccaggac gcactttctg cagcccactt attactacgc gatcgcctgc
    93121 tttcagacct tctgtcacca gccacttatc gccgatagcc tggcttgcaa cgatcggacg
    93181 ggtttccact ttgtcatccg cgccaaccac cagtacggtg gcatcgccac gtggcgtacg
    93241 ggttacgccc tgttgcggga ctaaaatagc gtttggatta agcccttctt ccagacgtgc
    93301 acgcacgaac atacccggca gcagagtgtg atccgggttc gggaagatag cgcgtagggt
    93361 gatagaccca gtggtctgat caacggtaac gtcagagaat tccagcgtac cgtcctgcgg
    93421 gaacttaatg ccgtcactgg tgatcagcga cactttggct ttgccgttct cttgtttcag
    93481 cgtgccattc gccagttcct gtttcaggcg caggaagtcg ttgctggact gggtcacatc
    93541 aacgtagatc ggatcaagtt gctgcacggt tgccagcgca gtcgcctgac cgttctgtac
    93601 caatgcgcct tccgtcacgt ttgacttacc aatgcgacca ctaatcggag aggtgacttt
    93661 ggtgtaagcc agattgattc gcgcagtttc aacggcagct ttcgccgcag ttaccgcagc
    93721 attcgcctgt tgcgcatcag ccagagcctg atcgtactct tgtttactga tgtactgagt
    93781 accgagcaat ttctgataac gattcaccgt caattgcgcg atattggctg cagcctgggc
    93841 tttcgccaga tcacctttcg cactgtcgta tgccgcctga taggtcgcag gatcaatctg
    93901 atagagagag acacctgctt cgatgtcgct accttctttg aaattacgct tcaggataat
    93961 cccgctaact tgaggacgaa cttctgcgat ccggtaggca ctggtgcgac ccggaagctc
    94021 ggttgtgatc tgcagaggtt cagttttgac tgttactacg ccaacggcgg gcatctgctg
    94081 gccaccttgt tgggcctgtt tgtcgtcaca tcctgttagg gctaagctgc ctgagagcat
    94141 cagaacgacc gccagaggcg taaaccctct gtttttgttc atatgtaaac ctcgagtgtc
    94201 cgatttcaaa ttggtcaatg gtcaaaagtt aataaaccca ttgctgcgtt tatattatcg
    94261 tcgtgctatg gtacatacat tcacaaatgt atgtaaatct aacgcctgta aattcacgaa
    94321 catatggcac gaaaaaccaa acaagaagcg caagaaacgc gccaacacat cctcgatgtg
    94381 gctctacgtc ttttctcaca gcagggggta tcatccacct cgctgggtga gattgcaaaa
    94441 gcagctggcg ttacgcgcgg tgcaatctac tggcatttta aagacaagtc ggatttgttc
    94501 agtgagatct gggaactgtc agaatccaat attggtgaac tcgagcttga gtatcaggca
    94561 aaattccctg gcgatccact ctcagtatta agagagatat taattcatgt tcttgagtcc
    94621 acggtgacag aagaacggcg tcgattattg atggagatta tattccacaa atgcgaattt
    94681 gtcggagaaa tggctgttgt gcaacaggca caacgtaatc tctgtctgga aagttatgac
    94741 cgtatagaac aaacgttaaa acattgtatt gaagcgaaaa tgttgcctgc ggatttaatg
    94801 acgcgtcgcg cagcaattat tatgcgcggc tatatttccg gcctgatgga aaactggctc
    94861 tttgccccgc aatcttttga tcttaaaaaa gaagcccgcg attacgtcgc catcttactg
    94921 gagatgtatc tcctgtgccc cacgcttcgt aaccctgcca ctaacgaata accctgaatc
    94981 tgactccagg aattttcctg gacattttcg tcgttgctat tctggttcac tgcgtcgtga
    95041 tattcttgcg gtttgacttt ttcaggtcgt tcttcaggtt cagaaacctt cattcatcat
    95101 gactatgttc cagtattaca aacgatcacg gcattttgtt ttttcagcat ttattgcttt
    95161 tgtttttgtc ttgttatgcc agaacacggc gtttgcacgg gcgtcatcga atggtgattt
    95221 accgacaaaa gcggacctgc aggcacaact tgactcactg aataaacaaa aagatctttc
    95281 tgctcaggac aaactggtgc agcaggatct gacagataca ttagccaccc tcgataaaat
    95341 cgatcgcgta aaagaagaga cagttcagct acggcaaaaa gtcgctgaag cgccggaaaa
    95401 aatgcgccag gcgaccgcgg cgttaacagc acttagtgat gtcgataacg acgaagaaac
    95461 gcgcaaaatt ctgagcgcgc tttcgttgcg ccagctggaa actcgcgttg cccaggcgct
    95521 ggacgatttg caaaacgcac aaaatgatct ggcgtcttat aacagccaac tggtttcgtt
    95581 acagacgcag cccgaacgcg tgcaaaatgc gatgtataac gcttcgcagc agctgcaaca
    95641 aattcgcagt cgtctggatg ggactgatgt cggcgagact gccttacgtc ccagccagaa
    95701 agtgttaatg caggtccagc aggctttgct gaatgccgag attgaccagc agcgtaaaag
    95761 cctggaaggg aacactgtct tgcaggatac cttgcaaaag cagcgtgatt acgtgacggc
    95821 gaacagcgcc cgtctggagc accagttaca actgttgcaa gaagcggtaa acagcaagcg
    95881 cctgacttta accgaaaaaa cggcgcagga agctgtctcc ccggatgaag ccgcgcgtat
    95941 tcaggctaat ccgctggtga agcaggaact ggaaattaac cagcagttaa gtcagcgtct
    96001 gattaccgcg actcaaaacg gtaatcagtt gatgcagcaa aacattaaag tcaaaaactg
    96061 gctggagcgt gcgctgcaat cggaacgtaa tattaaggag cagattgccg ttctgaaggg
    96121 cagtctgctg ttgtcacgta tcctgtacca gcaacaacaa acactcccct cggcagatga
    96181 actggaaaac atgaccaacc gcatcgcgga tttgcgtctc gaacagtttg aagtcaacca
    96241 gcagcgtgac gcgctgttcc agagcgatgc gttcgtcagc aaactggaag aaggtcacac
    96301 caacgaagtc aacagcgaag ttcacgatgc attattgcaa gtagttgata tgcgtcgcga
    96361 attgctggat cagcttaaca aacagttggg taatcagctg atgatggcca ttaacctgca
    96421 aattaaccag cagcagttaa tgagcgtatc gaaaaatctg aaatccatcc tgacgcagca
    96481 aattttttgg gtgaacagta accgcccgat ggactgggac tggattaaag cgttcccgca
    96541 aacgctgaaa gatgaattta agtcgatgaa aatcacggtg aactgggaaa aagcctggcc
    96601 cgccgtattc atcgccttcc tcgctggttt gccgctgctg ttgattgccg ggctgatcca
    96661 ctggcgtctg ggctggctga aagcgtatca acaaaaactg gcttccgctg tgggttccct
    96721 gcgtaacgac agccagctca acacaccaaa agcgatcctt atcgacctga tccgcgcact
    96781 gccggtgtgc ctgattattc tcgctgtcgg cctgattctg ctgactatgc agctcaatat
    96841 cagcgagtta ttgtggtcgt tcagcaaaaa actggcgatt ttctggctgg tgtttggcct
    96901 gtgctggaaa gtgctggaga aaaatggtgt tgccgtgcgt cactttggta tgccggaaca
    96961 gcagaccagc cactggcgtc ggcaaattgt ccgcatcagc ctcgcgttgc tgccgatcca
    97021 tttctggtct gtggtggcag aactctcccc gctgcatctg atggatgatg tgctggggca
    97081 ggcgatgatt ttcttcaacc tgctgctgat tgccttcctg gtgtggccga tgtgccgcga
    97141 aagctggcgt gataaagagt cgcacaccat gcgactggtc accattaccg tgctgtcgat
    97201 tatcccgatt gcgttgatgg tgctgaccgc cacgggttac ttctacacca cgctgcgcct
    97261 ctccgggcgt tggattgaaa ccgtttattt ggtgatcatc tggaacctgc tgtaccagac
    97321 ggtattgcgc ggcttaagcg tagcggcgcg gcgtatcgcc tggcgccgtg cactggcgcg
    97381 tcggcagaat ctggtgaaag agggcgcaga aggtgccgaa ccgccggaag aacccaccat
    97441 tgcgctggag caggttaacc agcagacgct gcgtattacc atgttgctga tgtttgcgct
    97501 gttcggtgtc atgttctggg caatttggtc tgatttgatc accgtgttca gctatctcga
    97561 cagcattacg ctctggcatt acaacgctac tgaagctggt gctgcggtgg tgaaaaacgt
    97621 caccatgggc agtctgttgt ttgcgattat cgcctcaatg gtggcctggg cgttgattcg
    97681 caacctgcct ggtttgctgg aagtgctggt gctctcgcga ctgaatatgc gccagggcgc
    97741 gtcgtatgcc attactacca tccttaacta catcattatt gccgttggtg cgatgacggt
    97801 gttcggatcg ctgggcgtct cgtgggataa actccagtgg ctggcggcag cattatccgt
    97861 aggtcttggt tttggtttac aagagatctt cggtaacttc gtttccggtt tgatcattct
    97921 gttcgaacgt ccggtgcgca ttggcgacac ggtaaccatt ggtagcttct cgggtacggt
    97981 cagcaagatc cgtattcgtg cgacaacgat taccgatttc gatcgcaaag aagtgattat
    98041 cccgaacaaa gcgtttgtta ccgagcgtct gatcaactgg tcgttgactg acacgactac
    98101 gcgtctggtg atccgtctcg gcgtagccta tggctccgat ctggaaaaag tgcgtaaagt
    98161 gttgctgaag gcggcgactg agcacccaag ggtgatgcac gaaccaatgc cggaagtctt
    98221 ctttacggca tttggtgcca gcacgttgga tcatgagctg cgtctgtatg tgcgtgaact
    98281 gcgtgaccgt agccgtactg tcgatgagct gaaccgtact attgatcagt tgtgccgtga
    98341 aaacgacatc aacattgcct ttaaccagct tgaagtgcat ctgcacaacg agaagggcga
    98401 tgaagtgacg gaagtgaaac gcgactacaa aggcgacgat ccgacgccag cggtagggta
    98461 aggacaataa agggcgacag tgatgccgcc ctttattttt tactcgcttt gtgaagtctc
    98521 atcgctctgt aacttctttt cataatcgcg ttttacaata tccagcgcgc gcagcacggt
    98581 gcgggctggg atctgatttt cttccagcag cacaatcaaa tcgacggcca gtttgacatc
    98641 gtcaggggca ttttccagtg acatactctc tccattgcta gcgggttaaa cgcgctaacc
    98701 tgttttcgat tttttccagc gcatggcggc aacgtgccag gcgcgcttca taggcttcca
    98761 cttcacgatg cagcgtctgc tgttccacga gatcggtcgc tcgcgccaga cgggctctac
    98821 gttcggcaac catctcacgt agccgccgct caaaatcctg atgctgaata cgtttacgct
    98881 gccagcgggc aattttcggt ggtgcgctat cccactcgcg tagcgaccag gctgtggctt
    98941 cacgcgctat agcctccagt tgcgccgcca gatgttctgc cagccaggcg acttgcggca
    99001 gctgttgctg ctcaaccgca tgacgaagcg cagccaggtt atcgcccgac tcatcgagac
    99061 aagcctgtag tgttgtcgca cgggtctgaa aaaggtgcct gtcaaaacgg gcacttagcg
    99121 tggcaaattg cgctaccggg gcacaacgct gacgcagcgt ggcgagctgt ccttccagtt
    99181 tttccagtag cagggcggtt ttcacgataa gacctcaatg aaaatgataa ttgttatgct
    99241 aaagtagcca ctctgtaagc tgacaacact caatatgcaa cgaatcattt taatcatcat
    99301 tggctggctg gcggtagtgc tgggtacgct gggcgtggta ttaccggtat taccgacgac
    99361 gccgtttatc ctgctggcgg cctggtgctt tgcccgttct tccccgcgct ttcacgcctg
    99421 gttgctgtac cgctcatggt ttggcagcta tctacgtttc tggcagaaac atcatgcgat
    99481 gccgcgcggc gcaaaaccac gggcgatttt gcttattttg attacgttta cgatttcgct
    99541 gtggttcgtc cagatgccgt gggtgcgcat catgttgctg gtaattctcg cctgtttgct
    99601 tttttatatg tggcgaattc cggtgattga tgaaaagcaa gaaaagcact gaagcacaac
    99661 aatcgcagtt gcaattattg cgtacagcca gtacattctg gcgttttcga gcacaggcgc
    99721 aggcggtcaa aggttaaaca actgttactt ttgatacgtt caaaacgcgc cgtgagtacc
    99781 accgtaacaa gcaggcatac acttatgacc gcgactgcac agcagcttga gtatctcaaa
    99841 aatagcatca aaagcattca ggactaccca aaacccggca ttcttttccg cgatgtcacc
    99901 agcttactgg aagacccgaa agcttacgct ctcagcatcg acttgctggt tgagcgttac
    99961 aaaaatgcgg gcattaccaa agtggtcggc accgaagcgc gtggcttctt gtttggcgct
   100021 ccggtagctc tgggtctggg cgttggcttt gtaccggtcc gtaaaccggg caaactgccg
   100081 cgtgaaacca tcagtgaaac ttacgacctg gaatacggca ccgatcaact ggaaatccac
   100141 gttgatgcca tcaaaccggg cgacaaagtt ctggtggtgg acgatctgct ggcaaccggc
   100201 ggcactatcg aagcgaccgt taaactgatc cgtcgtctgg gtggtgaagt agctgacgct
   100261 gcgttcatta tcaacctgtt cgatctcggc ggtgaacagc gtctcgaaaa acagggcatt
   100321 accagctaca gccttgtccc gttcccgggc cattaattat cgtcagtctt gcgctgctca
   100381 cgctacgggc agcacaagat gtgcattcag cctcgccgtt ctgacggggc tgtgttagca
   100441 ttaccccttc gtgaatccac cttccagcgt ttcagagcct gccaatgagt tatcaggtct
   100501 tagcccgaaa atggcgccca caaacctttg ctgacgtcgt cggccaggaa catgtgctga
   100561 ccgcactggc gaacggcttg tcgttagggc gtattcatca tgcttatctt ttttccggca
   100621 cccgtggcgt cggaaaaacc tctatcgccc gactgctggc gaaggggcta aactgcgaaa
   100681 ccggcattac cgcgacgccg tgcggcgtgt gcgataactg tcgtgaaatc gagcaggggc
   100741 gctttgtcga tctgattgaa atcgacgccg cctcgcgtac caaagttgaa gatacccgcg
   100801 acctgctgga taacgtccag tacgctccgg cgcgtggtcg tttcaaagtt tatctcatcg
   100861 acgaagtgca tatgctgtcg cgtcacagct ttaacgcact gttaaaaacc cttgaagagc
   100921 cgccagagca cgttaagttt ttgctggcga cgaccgatcc gcagaaattg ccggtgacga
   100981 ttttgtcacg ctgtctgcaa tttcatctca aggcgctgga tgtcgagcaa attcgccatc
   101041 agcttgagca catcctcaac gaagaacata tcgctcacga gccgcgggcg ctgcaattgt
   101101 tggcacgcgc cgctgaaggc agcctgcgag atgccttaag tctgaccgac caggcgattg
   101161 ccagcggtga cggccaggtt tcaacccagg gggtcagtgc gatgctgggt acgcttgacg
   101221 acgatcaggc gttatcgctg gttgaagcga tggtcgaggc caacggcgag cgcgtaatgg
   101281 cgctaattaa tgaagctgct gcccgtggta tcgagtggga agcgttgctg gtggaaatgc
   101341 tcggtctgtt gcatcgtatt gcgatggtac aactttcgcc tgctgcactt ggcaacgaca
   101401 tggccgccat cgagctgcgg atgcgtgaac tggcgcgcac cataccgccg acggatattc
   101461 agctttacta tcagacgctg ttgattggtc gcaaagaatt accgtatgcg ccggaccgcc
   101521 gtatgggcgt tgagatgacg ctgctgcgcg cactggcgtt ccatccgcgt atgcctctgc
   101581 ctgatccaga agtgccacgc cagtcctttg cgcccgtcgc gccaacggca gtaatgacgc
   101641 caacacaggt gccgccgcaa ccgcaatcag cgccgcagca ggcaccgact gtaccgctcc
   101701 cggaaaccac cagccaggtg ctggcggcgc gccagcagtt gcagcgcgtg cagggagcaa
   101761 ccaaagcaaa aaagagtgaa ccggcagccg ctacccgcgc gcggccggtg aataacgctg
   101821 cgctggaaag actggcttcg gtcaccgatc gcgttcaggc gcgcccggtg ccatcggcgc
   101881 tggaaaaagc gccagccaaa aaagaagcgt atcgctggaa ggcgaccact ccagtgatgc
   101941 agcaaaaaga agtggtcgcc acgccgaagg cgctgaaaaa agcgctggaa catgaaaaaa
   102001 cgccggaact ggcggcgaag ctggcggcag aagccattga gcgcgacccg tgggcggctc
   102061 aggtgagtca actttcgcta ccaaaactgg tcgaacaggt ggcgttaaat gcctggaaag
   102121 aggagagcga caacgcagta tgtctgcatt tgcgctcctc tcagcggcat ttgaacaacc
   102181 gcggcgcaca gcaaaaactg gctgaagcgt tgagtacgtt caaaggttca acggttgaac
   102241 tgactatcgt tgaagatgat aatcccgcgg tgcgtacgcc gctggaatgg cgtcaggcga
   102301 tatacgaaga aaaacttgcg caggcgcgcg agtccattat tgcggataat aatattcaga
   102361 ccctgcgtcg attcttcgat gcggagctgg atgaagaaag tatccgcccc atttgatcgt
   102421 aagcacagct tacgttcgtc atccttaacg tgattgagag agaaacctat gtttggtaaa
   102481 ggcggtctgg gtaacctgat gaagcaagcc cagcagatgc aagaaaaaat gcagaaaatg
   102541 caggaagaga tcgcgcagct ggaagtcacc ggcgaatctg gcgcaggtct ggtaaaagtg
   102601 accatcaacg gtgcacacaa ctgccgtcgc gtagagatcg acccgagcct gctggaagac
   102661 gacaaagaga tgctggaaga cctggtggct gcagcattca acgacgcagc acgtcgtatt
   102721 gaagaaacgc agaaagaaaa aatggcctct gtatcctccg gaatgcagct gccgcctggc
   102781 tttaagatgc cgttctgatg caaaccagcc cgctgttaac acagcttatg gaagcactgc
   102841 gctgtctgcc gggcgttggc ccgaagtcgg cgcagcgtat ggcgttcacg ctgcttcagc
   102901 gcgatcgtag cggcgggatg cgtctggcgc aggcgctcac ccgggcgatg tcggaaatcg
   102961 gccactgcgc cgattgtcgc accttcaccg aacaggaagt ctgtaacatc tgttcgaatc
   103021 cacgtcgtca ggaaaacggt caaatctgcg tggtggagag tccggcggac atttacgcca
   103081 tcgagcagac ggggcagttt tcaggtcgtt attttgtgtt gatgggacac ctgtcaccgc
   103141 tggacggcat cggtcctgat gatatcgggc ttgatcgtct ggaacagcgt ctggcagagg
   103201 aaaaaatcac tgaagtgatc ctcgccacca accccacggt tgaaggtgaa gctaccgcta
   103261 actacattgc cgagctttgt gcgcaatatg acgtggaagc cagccgaatc gctcatggcg
   103321 taccggttgg cggcgaactg gaaatggtcg atggcaccac gctgtcacac tcccttgccg
   103381 ggcgtcataa gattcgtttt taagcaaacg agagcaggat cacctgctct cgcttgaaat
   103441 tattctccct tgtccccatc tctccctcat cctgttttta accttaaaat ggcattattg
   103501 aggtagacct acatgaaagg acaagaaact cgtggttttc agtcagaagt gaaacagctt
   103561 ctgcacctga tgatccattc tctctattcc aataaagaaa tcttcctgcg tgagcttatc
   103621 tctaacgcct ccgatgcggc ggacaagctg cgtttccgcg cgctttctaa cccggacctg
   103681 tacgaaggtg atggtgaact acgcgttcgt gtctctttcg ataaagacaa gcgcacgctg
   103741 accatctccg ataacggcgt ggggatgacc cgcgacgaag tgattgacca tctggggact
   103801 atcgctaaat ccggcaccaa atcattcctc gaatccctgg gttctgacca ggcgaaagac
   103861 agccagctga tcggtcagtt tggtgttggt ttctactctg cgtttatcgt ggctgacaaa
   103921 gtgaccgtgc gtactcgcgc ggcaggcgaa aaaccagaaa acggcgtctt ctgggaatcg
   103981 gctggcgaag gtgaatacac cgttgccgac atcactaaag aagatcgtgg tactgaaatc
   104041 accctgcatc tgcgtgaagg cgaagacgag ttcctcgatg actggcgtgt gcgttccatc
   104101 atcagcaaat attccgacca tatcgcgctg ccggtagaga tcgaaaaacg cgaagagaaa
   104161 gacggcgaaa ccattatctc ctgggagaaa atcaacaaag cgcaggcgct gtggactcgt
   104221 aacaagtcgg aaatcaccga tgaagagtac aaagagttct acaaacacat cgcccacgac
   104281 tttaacgatc cgctgacctg gagccacaac cgcgttgaag gtaagcagga gtacaccagc
   104341 ctgctgtaca ttccgtctca ggcaccgtgg gatatgtgga accgcgatca taaacacggt
   104401 ctgaaactgt atgttcagcg tgtgttcatc atggacgacg cagaacagtt catgccgaac
   104461 tatctgcgct tcgtgcgtgg tctgattgac tccagcgatc tgccgctgaa cgtttcccgt
   104521 gaaatcctcc aggacagcac ggtaacgcgt aacctgcgca atgcgctgac caagcgtgtg
   104581 ctgcaaatgc tggaaaaact ggcgaaagac gacgcggaaa aataccagac cttctggcaa
   104641 cagtttggcc tggtactgaa agaaggtccg gcggaagatt tcgctaacca ggaagcgatc
   104701 gccaaactgc tgcgttttgc ttctacccat accgattctt ctgcgcagac cgtgtctctg
   104761 gaagactacg tttcccgcat gaaagaaggg caggagaaaa tctactatgt caccgcagac
   104821 agctacgcgg cagcgaagag cagcccgcac ctggaactgc tgcgtaagaa aggcatcgaa
   104881 gttctgctgc tttccgaccg catcgatgag tggatgatga actatctgac tgagttcgac
   104941 ggtaaaccgt tccagtctgt gtctaaagtt gacgagtcgc tggaaaaact ggctgacgaa
   105001 gttgatgaga gcgcgaaaga agcggagaaa gcactgactc cgttcatcga ccgtgtgaaa
   105061 gccctgctcg gcgagcgcgt gaaagatgtc cgtctgactc accgtctgac cgatacgcca
   105121 gcgatcgttt cgaccgacgc ggacgaaatg agcactcaga tggcgaaact gttcgctgcg
   105181 gcgggccaga aagtgccaga agtgaaatac atcttcgaac tgaacccgga tcacgtactg
   105241 gtgaaacgtg cggcggatac tgaagatgaa gcgaagttca gcgagtgggt agaactgctg
   105301 ctggatcagg cgctgctggc agaacgcggc acgctggaag atccgaacct gtttattcgt
   105361 cgtatgaacc agctgctggt ttcctgatgt catgccggat gaccttcgtg tcatccggca
   105421 tttttctttt cttcatctgc actttccgca aattatcttg ccattaaccg tttcagcctc
   105481 aggtgccttt cttgaggcaa tcgcctgttg gtggtatcgt ttatcgcttt ttcaaaaaat
   105541 tcgacacatt ttaaggggat tttcgcaatg cgtatcattc tgcttggcgc tccgggcgcg
   105601 gggaaaggga ctcaggctca gttcatcatg gagaaatatg gtattccgca aatctccact
   105661 ggcgatatgc tgcgtgctgc ggtcaaatct ggctccgagc tgggtaaaca agcaaaagac
   105721 attatggatg ctggcaaact ggtcaccgac gaactggtga tcgcgctggt taaagagcgc
   105781 attgctcagg aagactgccg caacggtttc ctgttggacg gcttcccgcg taccattccg
   105841 caggcagacg caatgaaaga agcgggcatc aatgttgatt acgttctgga attcgacgta
   105901 ccggacgaac tgattgttga ccgtatcgta ggccgccgcg ttcacgcgcc gtctggtcgt
   105961 gtttatcacg ttaaattcaa tccgccgaaa gtagaaggca aagacgacgt taccggtgaa
   106021 gagctgacta cccgtaaaga cgatcaggaa gagaccgtac gtaaacgtct ggttgaatac
   106081 catcagatga ctgcaccgct gatcggctac tactccaaag aagcggaagc gggtaacacc
   106141 aaatacgcga aagttgacgg caccaagccg gtggctgaag ttcgcgctga tctggaaaaa
   106201 atcctcggct aatcaagccg cagcagatct gctttcgggc aggtctgctc atcctcctca
   106261 ggcaatacct cttacagcaa ttagttcttc ttcttcactt ttccgctaca attatcaaca
   106321 agttgaatcg ataagaggcg gtaatgcgtc agactaaaac cggtatcctg ctggcaaacc
   106381 tgggtacgcc cgatgccccc acacctgaag cggtaaaacg ctatctgaaa caatttttaa
   106441 gcgacagacg cgtggttgat acctcacggt tgttatggtg gccgttgctg cgcggcgtga
   106501 ttttgccgct gcgttcgccg cgtgtggcga agctgtatgc ctctgtctgg atggaaggtg
   106561 gctcgccgct gatggtttac agccgccagc aacagcaggc gctggcgcaa cgtttaccgg
   106621 agacgcccgt ggcgctggga atgagctacg gctcgccatc actggaaagc gccgtagatg
   106681 aacttctggc agagcatgta gatcatattg tggtgctgcc gctttatccg caatactcct
   106741 gttcaacggt cggtgcggta tgggatgaac tggcacgcat tctggcgcgc aaacgtagca
   106801 ttccggggat atcgtttatt cgtgattacg ccgataacca cgattatatt aatgcactgg
   106861 cgaacagcgt acgtgcttct tttgccaaac atggcgaacc ggatctgctg ttgctctctt
   106921 atcatggcat tccccagcgt tatgcagatg aaggcgatga ttacccgcaa cgttgccgca
   106981 caacaactcg cgaactcgct tccgcactgg agatggcacc ggaaaaagtg atgatgacct
   107041 ttcagtcgcg ctttggccgg gaaccctggc tgatgcctta taccgacgaa acgctgaaaa
   107101 tgctcggaga aaaaggcgtg ggtcatattc aggtgatgtg cccgggcttt gctgcggatt
   107161 gtctggagac gctggaagag attgccgagc aaaaccgtga agtcttcctc ggcgctggcg
   107221 ggaaaaaata cgaatatatt ccggcgctta atgctacacc ggagcatatc gaaatgatgg
   107281 ctaatcttgt tgccgcgtat cgctaaagct gagcggtaaa gaactgagcg ccgtcgcgaa
   107341 gagcctcgtc ggcggttttc atcatccgtg aataatgcaa aaaggcgtgc agcgtgcctg
   107401 ggtagagttt gaactcacag ggctgctgat gcgccgctaa cgtctggtaa agcagatggc
   107461 tgtcatccag cagcggatcg aactccgccc cggcaataaa acagggcgga acttcgcgag
   107521 tgagatcatt attaaacagg cagtaatatg gcgactcgcg gtccgcgtcg ttgcttaaat
   107581 acgcctcttc atacatctgc aaatcctgtt gcgttaagcc atcccagaca ccacccaaca
   107641 gacgacgagc cacggaatcc cgtaatccgt aaagcccata ccacagcaaa acgcccgcaa
   107701 ctttaccgca atcgatctgt ttatcgcgca accacaacgc actggcgagc gccagcatgg
   107761 cacctgcgga atcaccggca aaaccaatgc gggacatatt gatttgataa tcctccgcct
   107821 gctggtggaa ataacaacag gcagccacaa tttcctctat cgcttgcgga aaacgcgctt
   107881 caggtgaaag ggtgtaatca atgccaatca ccgtacattg gctgtagctt gccagcaggc
   107941 gcatgatgcg atcgtgggta tcgagattgc cgagaataaa accgcctcca tgcaaataaa
   108001 atagcgtcgc cgggctatct ggctgcggat aaaagatacg tgttttcacc tgcccatatt
   108061 ttgttggaac cctgtaagct ctggttgcca tttctggagc gtccgcattc cagaatcggc
   108121 gctcaagcgt gtaatactgt cgttgctcag caatcgctcc cgttgcaggc cagggcggta
   108181 aatccggctg aagagtattc acaacggtct tcatttcagc agagataagg tccagaacgg
   108241 gtaatttgtt ttccggcttc atgcaaaaac tcctttcaaa ttacgtcatt gtaaggaacc
   108301 actgccatga aaatgcgatc ccgcctgctg atattgaaac tggctgcgtc tcgcgcgctc
   108361 ccgtcagatt gtgttaacat tcgccgctca gttaaccacc cgtaaaaaca accatgaaat
   108421 ttcccggtaa acgtaaatcc aaacattact tccccgtaaa cgcacgcgat ccgctgcttc
   108481 agcaattcca gccagaaaac gaaaccagcg ctgcctgggt agtgggtatc gatcaaacgc
   108541 tggtcgatat tgaagcgaaa gtggatgatg aattcattga gcgttatgga ttaagcgccg
   108601 ggcattcact ggtgattgag gatgacgttg ccgaagcgct ttatcaggaa ctaaaacaga
   108661 aaaacctgat tacccatcag tttgcgggtg gcaccattgg taacaccatg cacaactact
   108721 cggtgctcgc ggacgaccgt tcggtgctgc tgggcgtcat gtgcagcaat attgaaattg
   108781 gcagctatgc ctatcgttac ctgtgtaaca cctccagccg taccgatctt aactatctac
   108841 aaggcgtgga tggcccgatt ggtcgttgct ttacgctgat tggcgagtcc ggggaacgta
   108901 cctttgctat cagcccgggc cacatgaacc agctgcgggc tgaaagtatt ccggaagatg
   108961 tgattgccgg agcctcggca ctggttctca cttcttatct ggtgcgttgc aagccgggtg
   109021 aacccatgcc ggaagcaacc atgaaagcca ttgagtacgc gaagaaatat aacgtaccgg
   109081 tggtgctgac gctgggcacc aagtttgtca ttgccgagaa tccgcagtgg tggcagcaat
   109141 tcctcaaaga ccacgtctct atccttgcga tgaacgaaga tgaagccgaa gcgttgaccg
   109201 gagaaagcga tccgttgttg gcatctgaca aggcgctgga ctgggtagat ctggtgctgt
   109261 gcaccgccgg gccaatcggc ttgtatatgg cgggctttac cgaagacgaa gcgaaacgta
   109321 aaacccagca tccgctgctg ccgggggcta tagcggaatt taatcagtat gagtttagcc
   109381 gcgccatgcg ccacaaggat tgccagaatc cgctgcgtgt ctattcgcac attgcgccgt
   109441 acatgggcgg gccggaaaaa atcatgaaca ctaatggagc aggggatggc gcactggcag
   109501 cgttgctgca tgacattacc gccaacagct accaccgtag caacgtacca aactccagca
   109561 aacataaatt cacctggttg acgtattcgt cattagcgca ggtgtgtaaa tatgctaacc
   109621 gtgtgagcta tcaggtactg aaccagcatt cacctcgttt aacgcgcggc ttgccggagc
   109681 gtgaagacag cctggaagag tcttactggg atcgttaagt tatcgtcggt tcgtaggcca
   109741 gataaggcgt tcacgccgca tctggcattt tgctctcaat gcctgatgcg acgctggcgc
   109801 gtcttatcag gcctacatat ccgcgcctat tatccggcaa ccaccgttta cctcgtcacc
   109861 acctcacccg ccggtggcgt ttccagcagt tccagcatag tacgggcaat ttcacgctca
   109921 cccatcacta cctgattcgc accacgttcg gtgatatacg ccacttcatc gtcataatgg
   109981 gcgcgggcaa taatctcaat atccggattt ttcgcgcggg cagatgccac aatctcgccc
   110041 gcttcatagc cgttgggaat cgtcaggatc agccattttg cacattccag atgcgccagt
   110101 tgcataattt cttcgttagc cgcattgccc aatactgcgc ggaccccgcg ctcgcgcagc
   110161 tcatcaacac gggttcgtga cgtctcaatc accaccagcg gaatatcaga ggcgagcaat
   110221 ttctccccca gcaggctgcc tacacgaccg taacccacca gtagcgcatg gttgcaaata
   110281 tccactggga tctgcttctc ttcttcgatt gcctcttcca gcgtctgctc ttccagcgtt
   110341 tcggtcttcg ccagatattt ctccagtagt gcgaacagta ccgggttgag cataatcgac
   110401 aggatcgccc ctgccagtac caggttttgt ccggcctgcg gcagtaaatt caatgccatt
   110461 cctagtcccg ccaggataaa cgcgaactca ccaatctgcg ccaggctggc ggcgatggtt
   110521 aacgccgtgc gctgggagtg accaaacaaa cgcacaagga acagggccgc gaccgattta
   110581 ccaaacagaa taattgccag cgtcgccagt actgccagcg gttgctgaat cagaattaac
   110641 ggatcaaaca acatcccgac ggagacaaaa aacagcaccg caaacgcgtc gcgcaatggc
   110701 agtgtatcgt gggcggcacg gtgactcagt tcagactcgt tcagtaccat cccggcaaag
   110761 aacgcaccga gtgcaaagga gacatcaaac agctctaccg caccaaaggc aatccctaac
   110821 gccagcgcca gcaccgacag ggtaaacagc tcgcgggaac cggttgctgc gctgcgtgcc
   110881 ataatccacg gcaccagacg gcgacctacc agcatcataa tggcgataaa tgcgatcacc
   110941 ttgccgatgg tgatccccat atcgactgca agagtggcaa agcccacatc gccctgttcc
   111001 atcattcctg ctaccgcggg tagcaatacc agtgtcagga ccatcaccag gtcttccaca
   111061 atcaaccaac cgatggcgat ttgcccacgc tgactgtcaa ttaattgccg ttcttcaagt
   111121 gcgcgcagta acaccacggt actggcggtg gaaagacata agccgaacac gataccggtc
   111181 attaacgacc agcccagcac ggcggagagc gccataccca gcagcgtcgc cacggctatc
   111241 tgggcgatcg cgccgggaat ggcgatggac tttaccgcca tcaaatcctt gagcgaaaaa
   111301 tgcaaaccga cgccgaacat cagcaaaata acgcccagtt cagccagttc cggcgcaagc
   111361 ttagtatcgg caacaaagcc cggagtgaat ggtcctgcca gcacacccgc taacagatat
   111421 cccaccagag gagaaatacg tagtttattg gccagcatgc cgaggataaa ggcgagcaca
   111481 aggccgccaa caatggtggt gataagcggg gtggcgtgat gcattccgtc tccttttcct
   111541 ggtggttatt gtccattttt ggccgggaaa accaaaatta caggtaatag tttatgacaa
   111601 tttcattgat gatgtttatg aataattgtt gaattttgca gaaaaatgga attagctgca
   111661 aaaaaaagca cggatcggaa aacagaaggc ggtttaacag aggaaaggct tatggcgact
   111721 gtaaaacgat gcagccaaag tttgcctttg gctgcaatga aatcagtctt tatgccggtt
   111781 atcaggcagg aatatggtca acatccccaa tagtggcagg aaagcacaga ttttatagac
   111841 taactctatg ctggtgtggt cggcgataag ccccagaact gccgccccca gacctcccat
   111901 gccgaaagca aaaccgaaaa atagtccaga aaccataccg atacgtcccg gaagcagctc
   111961 ctgggcatag accagaatgg cagagaatgc cgaagcgagg ataaatccaa taatcaccgt
   112021 taaaaccccc gtccagtgca ggctggcgta gggtaaaatc agcgtaaacg gcgcaacgcc
   112081 gaggatagag ccccaaatca catatttccg tccaatttta tcccctacag gcccgccaat
   112141 caccgtacct gccgcaacgg caaacaggaa ggcaaacaaa tgaagctgag cattctggat
   112201 agataatccg aatttttgca tcagataaaa ggtgtaatag ctgctgatgc tcgccatata
   112261 gaaatatttc gagaaaatga ggattaacag aatgctgacc gccagaacaa ctttattgcg
   112321 cggcagtgga ttgataatcg tcgctttggg ttttccttta ttcattcggt gctgtgccga
   112381 gtaccaacgg ctgatttgcg ccaacaccac gatcgccagc agtgccgcaa gcacaaacca
   112441 ggcaacgttg cctttgccat aaggcgcgat aatcaccgcc gccagcaagg ggcccaggga
   112501 actgccaaag ttgccgccga cctgaaatat agattgcgcc aggccatgac gcccgccgga
   112561 agccatacgg gccacgcgag aagattccgg atgaaagacc gatgaaccgg taccgaccag
   112621 cgccgctgcc agcagaactg cgccgaaact gcccgccagc gccagcagca ccagaccact
   112681 taaggtaaag cacatgccaa tcggcaacga ccacggcatc ggatatttat cggtccagta
   112741 gccgaccacc ggttgcagta gcgaagaggc gagctggaag gtgagggtta tcatgccaat
   112801 ctgcataaat gtcagagaaa attctgactg aagcagtgga taaatcgcca gaatcagcga
   112861 ttggatcatg tcgttcagca gatgtgagag gctgatagca cctaaaatac caaacgatgt
   112921 tcgggcctta gtcgttgacg cagccgcgcc cgccacaggc tgggtttgtt cactcattgc
   112981 cataggaaag tcactttttc agggttgcga tgtaaagaat gatcttattt gtgattatta
   113041 cccgactaac atacctgtat gcgccgcctg aaggaagtct caacacggaa tacagaattt
   113101 ctaatctgga tgcagattta tcttcaccgg acgcagactt gtttatgatg tcgcgtcata
   113161 ctatttttca acacgttgaa atcaggtcag ggagagaagt atgaaattat tgcagcgggg
   113221 cgtggcgtta gcactgttaa ccacatttac actggcgagt gaaactgctc tggcgtacga
   113281 gcaggataaa acctacaaaa ttacagttct gcacaccaat gatcatcatg ggcatttttg
   113341 gcgcaatgaa tatggtgaat atggtctggc ggcgcaaaaa acgctggtgg atggtatccg
   113401 caaagaggtt gcggctgaag gcggtagcgt gctgctactt tccggtggcg acattaacac
   113461 tggcgtgccc gagtccgact tacaggatgc cgaacctgat tttcgcggta tgaatctggt
   113521 gggctatgac gcgatggcga tcggtaatca tgaatttgat aacccgctca ccgtattacg
   113581 ccagcaggaa aagtgggcta agttcccgtt gctttccgcc aatatctacc agaaaagtac
   113641 cggcgagcgc ctgtttaaac catgggcgct gtttaagcgt caggatctga aaattgccgt
   113701 tattggcctg acgacggatg acacagccaa aattggtaat ccggaatatt tcactgatat
   113761 cgaatttcgt aagcccgctg atgaagcgaa gctggtgatt caggagctgc aacagacaga
   113821 aaagccagac attattatcg cggcgaccca tatggggcat tacgacaatg gtgagcacgg
   113881 ctctaacgca ccgggcgatg tggagatggc acgcgcgctg cctgccggat cgctggcgat
   113941 gatcgtcggt ggtcactcgc aagatccggt ctgtatggcg gcagaaaaca aaaaacaggt
   114001 cgattacgtg ccgggtacgc catgcaaacc ggatcaacaa aacggcatct ggattgtgca
   114061 ggcgcatgag tggggcaaat acgtgggacg ggctgatttt gagtttcgta atggcgaaat
   114121 gaaaatggtt aactaccagc tgattccggt gaacctgaag aagaaagtga cctgggaaga
   114181 cgggaaaagc gagcgcgtgc tgtacacccc tgaaatcgct gaaaaccagc aaatgatctc
   114241 gctgttatca ccgttccaga acaaaggcaa agcgcagctg gaagtgaaaa taggcgaaac
   114301 caatggtcgt ctggaaggcg atcgtgacaa agtgcgtttt gtacagacca atatggggcg
   114361 gttgattctg gcagcacaaa tggatcgcac tggtgccgac tttgcggtga tgagcggagg
   114421 cggaattcgt gattctatcg aagcaggtga tatcagctat aaaaacgtgc tgaaagtgca
   114481 gccattcggc aatgtggtgg tgtatgccga catgaccggt aaagaggtga ttgattacct
   114541 gacagccgtc gcacaaatga agccagattc aggtgcctac ccgcaatttg ccaacgttag
   114601 ctttgtggcg aaagacggca aactgaacga cctgaaaatc aaaggcgaac cggtcgatcc
   114661 ggcgaaaact taccgtatgg cgacattaaa cttcaatgcc accggcggtg atggctatcc
   114721 gcgccttgat aacaaaccgg gctatgtgaa taccggcttt attgatgccg aagtgctgaa
   114781 agcgtatatc cagaaaagct cgccgctgga tgtgagtgtt tatgaaccga aaggtgaggt
   114841 gagctggcag taatgaaccc cgtcgcggcg tcatgatatg acgccgccat ttatgaatat
   114901 tgaaatcttg catcgtaatc gcgatgtgtc aaaccaaatg ccatcagcat ataattctgc
   114961 ggatcaccag gctgttcttc atctgcttca aaccaaagtg tcacgcctga gcgattgacg
   115021 tggattaaga gtgtatgggg cgattgacgg cggatttgca gatcagcgcc ttcgttaaca
   115081 agcatgttaa atacacgcgt aacgttcaac tcagcgacgt tattcaatat tcctttatca
   115141 aatcggatcg ctttgcccaa atggatttgg ctcagataat cgcaccaaat catatatagc
   115201 ttgttgtttt cgaaatgaaa ctcaacatta ccaaatagcc agatataaaa accatttccc
   115261 atatcatttt tagagtccgg ctcaacaaag ttttgttcca accatgccat tgtttgcccc
   115321 agttcgacaa aatcgaattt tccgttaaag acaaaattgt ggaagctaac atcaacaaga
   115381 tggtcaaatt tcatctttcg ctcctttgtg aattttttac atgcttcaaa agccagcgta
   115441 atttacatcg gtgcaggcga ctctccagtg ttgagcgaaa atttgcgatg tcgacattgg
   115501 accgatctac cgcagcaacc cccgtgtatt gtgggatcgg tgaagggatt ttttgtaact
   115561 ttcccagcgc cagcagttgt tgaatgatcc tgctaccgtc gtggtaatca tcgtaaatag
   115621 ccactggcag aggctgccag gcgggggtcg atttgataaa tccggaaaaa aaatacgggt
   115681 ccagatcgcc gaaatcaaag ccgtaggcga ggggaacttc aatattttgc tctgtttttt
   115741 tattctcaaa tgtacaatga aaaccgtgaa aacaatactg ccactttccc attttgcctt
   115801 ttcgcttacg gttgcatttg aagggggcaa aggtaactag cgggttattt tccgccatct
   115861 caacgttcag ttgttcagcc aatgcaaata taagctctgt cgccagctta cgatattctt
   115921 tcgcgcagtg ttcgaaaaaa tcctgatggc ggttaatctc ttcaagcgat attaatctgg
   115981 cgatcctgat aaccgggtcg gcagaatgca tgccaacaac aaattcatcg agctgtgctt
   116041 tcagcaccag cccgaattcc tcacgatacc tctctgcttc gctggcaaaa tgcagatgta
   116101 ataccttctc tctcgatgtt tgccgaagta aggcgatatc cggtatctca tctgcacaag
   116161 cgatacttaa tgtctctgta atcctttcca catctcatct tccgtgtgca tcacttaatc
   116221 gcgacgggcg atatcagcaa atttggcatc gagtatcttt gccaggtcgc ttgccgccag
   116281 ttcgatatcc agtccgcgct tgccgccgga aacataaata gtggcaaatt cttgtgcggg
   116341 ggcgtcgata atcgttggca gacgtttttt ctgccccagt gggctaatcc cccctaccag
   116401 ataccccgtc gaacgctgcg cgaccatcgg atcggccatc tcaactttct tggcacccag
   116461 cgcttttgct acttttttaa gatccagttg acctgcgacc ggcgtaacag ccacggcaag
   116521 gtgtttcata tcaccgttca ctgcgaccag cagcgttttg tagacctgat ccggattcaa
   116581 acctaatttt ttgacgactt catcgccaaa attggtttca gcaggatcgt gctcgtaggt
   116641 gtggatttga aacgaaatct tgtttttttc gagtaattta actgcgggtg tcatggtaat
   116701 tttcctgcct taaacaaaaa aacgaagcaa gcatacgcct gatggcggtc caaaaaaaag
   116761 agtcatcttg cctaagagta ttggcaggat ggtgagattg agcgacaatc gagttacacc
   116821 gtcgcttaaa gtgacggcat aataataaaa aaatgaaatt cctctttgac gggccaatag
   116881 cgatattggc cattttttta gcgcaacatc tgcggcaaat tcccttctcc atacaggtgt
   116941 agtgcaccga ccgcgaccac atagcgcccc ggcggcatgg cgcgtaattt gtcccgccag
   117001 gcgaggtttc gctgatgcat cagcacatcg tacagcgact gactgaacgt attgggcagc
   117061 gttatatcat tattttgcgg cggtgcattc agccaccagc tcatcatttg ttgcagcaac
   117121 cgtgcgttgg tgtgccagtg ggtcagcgta tcgtccagca gcgccagtcc tttgtcaggg
   117181 agctggagca acatggcaat ctggttttca gccccttcca gttcaatcac gggtttatgt
   117241 tgttgcttag ccgcctgcaa tagctggtaa tcgataccgt attctgcccg cagccccagt
   117301 ttttgcgcct gcgtcgcctg aagaaccatc gcgatttgcc acagcggttg ggtagaaaag
   117361 agcgacggag aaatgcccat ctcctggcta atgtgctgca ggttttggag ttggtcctcg
   117421 ctaatgcgct cttccagggc ctcgcaggca ggcaaattgg caaaaggcgt atcgctggtg
   117481 gaaacatccg cctcgacgat cagcgcatcg gcgtttttga gctttttgag caaacgggtg
   117541 ggcaggggag ccatatcgtg gctacccata tgaatactgc cgatcagatg aaaatggcga
   117601 ttgccgggaa gagagatatc gatagcaggc caggtgtaat gattaccgcg cagcgcggcc
   117661 caaagcgttt ttacccggta caacagatcc atacgacctc cctttgtgaa atatcatgct
   117721 agcgcgcggg gagggatggc gcaaatggag ttgattgttg cacttgtgca cagtgcttgt
   117781 gtgcattaca atgattaaat aatggacaag gagatgagag aggaatggct caaaagaaaa
   117841 atataaggag ttttcgtgat gcctggttgg ctgatttttt tgtccattca acgccacatc
   117901 gaaagatccc tgctgaaatc cataccacgt tatcacgaaa gttggacatc attaatgctg
   117961 ccacttctca tcgggattta cgctcccctc cggggaaccg atacgaagag ttatccggga
   118021 aattacagga atactcctcc attagagtga ataaacagta ccgactgatt tttaaatggg
   118081 ttaatggcaa ggccgaagaa ttgtttttag acccacacaa ctactaaaac atagctgtcg
   118141 tattgacgag aaaggtaaaa ctatgaaaca ggcaacaaga aaaccgacga cacccggaga
   118201 tattcttctc tatgaatatc tggaaccgct cgatttgaaa atcaatgagt tagcagagtt
   118261 gctgcatgtt catcgtaata gcgtcagtgc actgatcaat aacaatcgta aactcaccac
   118321 tgagatggca ttccgtctgg cgaaagtttt tgataccaca gtcgattttt ggctaaacct
   118381 ccaggcggca gttgatcttt gggaagttga aaacaacatg cgtacccagg aagaattggg
   118441 acggattgaa acagtggctg aatatttggc acgccgtgaa gagcgtgcaa aaaaggtcgc
   118501 gtagaataat ttccctataa cggatgcgcc accctaaagc agcgcatccg caatgatgta
   118561 cttattcctt cggtttaaac cgcagcaatc ggttggcgtt actcactacg gtgatcgacg
   118621 agagcgccat tgccgctccg gcaaccaccg ggttaagcag tgttccagtg aacggccaca
   118681 aaataccggc ggcgaccgga ataccaatgc tgttgtagat aaacgcaccg agcagattct
   118741 gcttcatgtt gcgcagcgtt gcgcgggaaa ttgcaagcgc atccgcaaca cccatcaggc
   118801 tatggcgcat cagggtaatc gccgcggttt caatggcaac atcactgccg ccacccatcg
   118861 caataccgac atccgcctga gccagcgctg gcgcgtcgtt aatgccgtcg cctaccattg
   118921 ccacctgacg tccttcactt tgcagacgtt tgatcgcttc ggctttaccg tctggcagca
   118981 cgccggctat cacctcatca atccctgctt ctttggcgat cgcattggcg gtggtcgggt
   119041 tatccccggt tagcatcacc aggcgatatc ccgctttatg caggcgttgc agcgccgcca
   119101 cgctatcact acgcaacgga tcgcgtacag ccagcagggc taccgctttc ccgtcaaccg
   119161 ccagcagcac aggcgttgcc ccttgcgatg cctgagctga aatatctgct tcaattgctt
   119221 tggtatcgac ctgttggtca tttaacagcg cctgattgcc cagcaataac gcatgacctt
   119281 cagcttcacc gctcacgccc agcccgcgca atgtgcggaa accgttgacc tgcggtagct
   119341 gcatatcacc tgctttatcg aggatcgccc gtgccagagg gtggctggaa ccttgctcca
   119401 gcgccgccgc cagacgcaat gcttgcgctt catcaatatc agcaaatgtt tttactgcga
   119461 caacctgcgg cttcccttcg gtcagcgtcc cggttttatc gaacactacg gtgtcgagcg
   119521 tactggcgcg ttgcagcgcg tcggcgtccc gtaccagcac gccaaactca gccgcccgcc
   119581 cgacgcccga aataatcgac atcggcgtcg ccagccccag cgcacacgga caggcaataa
   119641 tcagcaccgt ggtggcaatc accagggtat agacaatctg cggtgccgga ccaaagaaat
   119701 accagattgc cgcactgatc agcgcaatca ccaccactac cggcacaaat acggctgaga
   119761 ttttatccgc cagctgaccg atttctggct tactgctctg ggcctggcgc accatacgaa
   119821 taatccgcga cagcgtagta tggctgccaa ccgcactggc gcgaaacagc acgctaccgt
   119881 cctgcaccac tgtcccggca tggacgctat cgccttcgcc tttttgctgc gggataggtt
   119941 cgcccgtcag catcgcttca tccagccatg cttcgccctg ggtaatctct ccatctaccg
   120001 gtacgcgatc gccggtcgtc aggcgcagca acatacctgg ctgcacttcc gccagtggca
   120061 cgcttttttc accttcgtca gtaaccaggc gcgccgtcgg cggagttaaa tcgagcaatt
   120121 tctccagcgc ctttgaagaa cgctgacgtg cgcgcgcttc cagcatatga ccgagattaa
   120181 tcagaccgat aatcatcgca ctggcttcat agtaaagatg ccgcgcttcc atcgggaacc
   120241 actgcggcca caggttgacg ctcatcgaat agagccacgc cacacccgtt cccagcgcca
   120301 ccagcgtatc catcgtcgcc gcaccgttca gcaggctttt ccatgcgctg cggtaaaaat
   120361 gcccgccggc gaaaaccatt accgccaggg ttatcaggcc gataactaac cacaggctgc
   120421 ggttgtcagc ggtgaccatc atgttatcgc cgatcatccc ccagaccatc accgggatac
   120481 ccaccgccag cgcgacaatt gcctgccagc ggaagcgctt catcgtagcg acggcggttt
   120541 cttgctggcg ctcgcggcgt ttagcgtcat cttcaatcgc ttccgcgccg tagcccgctt
   120601 tttccaccgc ctgcactaaa tcttgtgggg aggcactgcc catcaccagc gcagtacgct
   120661 ccgccaggtt tacccgtgcc tgagtgacgc ccggtacgct ttgcaacgca ttttgtacgc
   120721 gggtgacaca gctggcgcag ctcatgccgc tcagcagcaa ctgctggctg tcatcgtcat
   120781 cggcggtcgc tgccggaagc gcctcagaaa ccgctgtcag tgcttccgac gggattgatg
   120841 actccgccag cggtttagcc tttgggtggc ttacagatgc gtcataaccc gcttgtttga
   120901 tggtttcgat tagctgttct gcactggcag tcccggtaac gtgcgcttca gtgatagaca
   120961 catccgcctg ttcaacatcc gggcgctgtt cgagactttc tttcacgcgt ttaacgcagt
   121021 gaccgcagga caggccgtcc agggtcaggt cgatagtttg tgacataaaa cactccttta
   121081 agacagtttt gactggctgt gataaaggtt aaaccttcca gcaaggggaa ggtcaagaaa
   121141 ttaataaacc aggcgggtaa aagtccgtaa agattaaaaa atcggctcga tttgcatcag
   121201 gattagacat ttatctcttt gttttcctgt agttaagttg cgggtgctaa gttaaatcag
   121261 gatgcatgaa aatcggcacc ggggtgagga attacctccc gcatctataa aaaggagtta
   121321 acaaaagatg ttagatgcaa acaaattaca gcaggcagtg gatcaggctt acacccaatt
   121381 tcactcactt aacggcggac aaaatgccga ttacattccc tttctggcga atgtccctgg
   121441 tcaactggcg gcagtggcta tcgtgaccag cgatggcaac gtctatagtg cgggtgacag
   121501 tgattaccgc tttgcgctgg aatccatctc gaaagtctgt acgttagccc ttgcgttaga
   121561 agatgtcggc ccgcaggcgg tacaggacaa agttggcgct gacccgaccg gattgccctt
   121621 taactcagtt atcgccttag agttgcatgg cggcaaaccg ctttcgccac tggtaaatgc
   121681 tggcgctatt gccaccacca gcctgattaa cgctgaaaat actgaacaac gctggcagcg
   121741 aattttacat atccaacaac aactggctgg tgagcaggta gcgctctctg atgaagtcaa
   121801 ccagtcggaa caaacaacca acttccataa ccgggccatt gcctggctgc tgtactcagc
   121861 cggatatctc tattgtgatg caatggaagc ctgtgacgtg tacacccgtc agtgctccac
   121921 gctcatcaat actattgaac tggcaacgct tggcgcgacg ctggcggcgg gtggtgtgaa
   121981 tccgctgacg cataaacgcg ttcttcaggc cgacaatgtg ccgtacattc tggccgaaat
   122041 gatgatggaa gggctgtatg gtcgctccgg tgactgggcg tatcgcgttg gtttaccggg
   122101 caaaagcggt gtaggtggcg gtattctggc ggtcgttcct ggcgtgatgg gaattgccgc
   122161 gttttcacca ccactggacg aagaaggcaa cagtgttcgc ggtcaaaaaa tggtggcatc
   122221 ggtcgctaag caactcggct ataacgtgtt taagggctga tcatgatgaa cacggaaggt
   122281 aataacggta acaaacccct cggtctatgg aacgtcgttt ccatcggcat tggggcaatg
   122341 gtgggggcgg ggatcttcgc gctgctgggg caggctgcgt tgctaatgga agcctcgacc
   122401 tgggtcgcct ttgcttttgg cggtattgtg gcgatgtttt ccggttatgc ctatgcgcgt
   122461 ctgggggcga gctatcccag caatggcggt attatcgact tctttcgtcg cggattaggc
   122521 aacggcgttt tttcgctggc gctctcgtta ttgtacctgt tgacgctggc ggtgagtatc
   122581 gccatggtcg cccgtgcttt tggcgcttat gccgtgcagt ttttgcatga aggcagtcag
   122641 gaggagcacc ttattttgct ctacgcattg gggatcattg cggtgatgac gcttttcaac
   122701 tccttaagca accatgcggt agggcggctg gaagtgatcc tcgtcggcat taaaatgatg
   122761 atcctgttat tgctgattat tgccggtgtc tggtcgctgc aaccggcgca tatttccgtt
   122821 tctgcgcccc ccagctccgg ggcgttcttc tcctgtatcg ggataacctt ccttgcctat
   122881 gcgggctttg gcatgatggc gaacgcggcg gataaagtga aagatccgga ggtcataatg
   122941 ccacgggcgt ttctggtggc gattggcgtt accacgttgc tttatatctc gctggcgctg
   123001 gttttgctta gcgatgtatc ggcattagag ttagaaaaat atgccgatac cgccgtagcg
   123061 caggctgctt ctccgctcct cgggcatgtg gggtatgtga tcgtcgtcat cggcgcttta
   123121 ctggcgacgg cttcagccat caacgcaaac ctgttcgccg tgtttaacat catggacaac
   123181 atgggtagcg aacgcgaact gccgaagcta atgaataaac ctctgtggcg gcagagtacc
   123241 tggggtaaca tcatcgtcgt ggtgttgatt atgctgatga cggcggcgct gaatttaggc
   123301 tcactcgcca gcgttgccag tgccaccttt ttgatctgct atctggcggt gtttgtggtg
   123361 gcgatccgcc tgcgtcatga tattcacgcc tcgttgccga ttcttatcgt tggtacgttg
   123421 gttatgttgt tggtgatcgt tggctttatc tacagtctct ggtcccaggg cagccgtgcg
   123481 ctgatatgga ttattggcgc actcttactc agccttattg tggcaatggt catgaagcgc
   123541 aataaaaccg tataacatct ctctgtgcgc agtacctcct gtattattgt ggtggcggtc
   123601 gatattcgca ctggcaaaaa aacgtgcttg aatatctgtt gaaacccttt aacaaagcac
   123661 aggaggcgtt gcgcgaacga tgaacattag cgatgtagca aaaattaccg gcctgaccag
   123721 caaagccatt cgcttctatg aagagaaggg gctggtgacg ccgccgatgc gcagcgaaaa
   123781 cggttatcgc acctacacgc agcagcatct caacgaactg accttactgc gccaggcacg
   123841 ccaggtgggc tttaacctgg aagagagcgg cgaactggtg aatctgttta acgatccgca
   123901 gcgtcacagc gccgacgtca aacgtcgtac gctggagaaa gtagcggaga tcgaacagca
   123961 tatcgaagaa ctgcaatcca tgcgtaacca gctgctggcg ctggcgaatg cctgccccgg
   124021 tgatgacagc gccgactgcc cgattatcga aaatctctcc ggctgctgtc atcatcgggc
   124081 ggggtgatta aggcttgcga aaatagtcgt ccattatttt cgttagctcc ggacgttccc
   124141 cgtcatcatt gatggcaaaa tccagaaaaa aagcatctgc ttgcggcgtt cggttttgcg
   124201 ccatcaaccg gaaggtgagg gggcctgacc aggtttcgga tgggctgatg tgcttatcag
   124261 ggccgaaact ctcccatgcg ctgggcggta atgttttgca cgcggtgagt tttggtatgt
   124321 ggtattgcag ctctgttttg tgcagacatt ccccgccagg aaataccagg gtttgttgct
   124381 catcattaaa atgggttgcc gtgctgagca ccagtgtttt gagcggtcgc ccttccagcg
   124441 cggcggcagt agccttatgg tgtccgtcga gtagaacgca gagataggaa tcagggagat
   124501 accaggccag accacgggca attccagttt tcgagagcag acaaaaaccg ggcggctccc
   124561 tgttcatcct ccgcaaaacc gctgtagaca aattccgcac aggtagggca tccagcctcg
   124621 gaccagaaac gtattaacgg gacatcctgc cagcagagcg aatggataag accgtgcgag
   124681 tgcggatcgt aaatcacaca ttgacgcaga aatcctttcc cggacttcac cgaaaaaatg
   124741 acgcccgcag cggtattttt cagcagacgt acttcaggtt ttcgaaaggg ggaaacatgg
   124801 ctactcctta gccgaacatt caattaacac tatgtggggg gctatatgcc ggatgcggcg
   124861 taaacgcctt atccggcatg ggttttggta cagatttcca ggtgtgataa gacgcgtcag
   124921 gcgatgaccg cacggataat cagcgttatt ccttctatcg caatcacctc aacatgcgta
   124981 ccagcgccga gatcctcgct ggcgctgaca ggccatgaac tgtcaccgac gcgcatatga
   125041 ccgcgcccgt tgaccagcgg agattccaga acaaaacgtc ggccaatcaa ctgctgcccg
   125101 cgctggttta aatgactgtc gctgtgcttt tgttcgcgca cccgccgcga caaccatttc
   125161 caccacagcc aggcggcgag cagcgtcagg acggcaaaca ttaccccttg ccactcccaa
   125221 cccagcggca gcaaccagac caccagaccg gtaatcaccg ctgccacgcc gctccacaac
   125281 agataaccat tgccgcccaa catctcggct gccagcagca aaccgccgag acttagccag
   125341 aaaatatgtg gatgaacgac cattaactcc atcatggctg agtccgtttg ttggcgctgt
   125401 ctttcaccag ctcagcaatc ccggcaatcg accccatcag gctgctggcc tctaatggca
   125461 tcatcaccac tttgctgtta ctggacgaac cgatctgctg taacgcttcg gtgtatttct
   125521 gtgcgacgaa gtagttcacc gcctgaatat caccggaggc gatggcttca gacaccattt
   125581 tggtggcgcg ggcttctgct tcagcggaac gttcacgcgc ttcagcctgt aaaaacgccg
   125641 actgacgttc gccttccgct ttcaggattt gtgactgttt ttcaccttcg gctttgagga
   125701 tttccgcctg acggatccct tccgcttcaa ggatgtaagc gcgtttggta cgttccgctt
   125761 tcatctgcgc gttcattgaa gagataagct ctgcgggcgg gcgcacatca cgaatttcga
   125821 tacgggtgac tttaatcccc cacgggttgg tggcctcatc gacaatatgc agcagacgcg
   125881 agttaatgct gtcgcgctga gagagcattt catcaagttc cattgaaccc agcacggtac
   125941 ggatgttagt catggtcagg ttgatgatcg ccagctccag attgctgact tcataagccg
   126001 cgcgcggcgc gtcaatcacc tgaataaagc acacagcgtc gatggtaacg ttggcgttat
   126061 ctttcgagat aacttcctgg gaagggatgt cgagcacttg ctccatcata ttgatcttgc
   126121 gaccaatgcg atccataaac ggcaccacca ggcttagacc tggctgtaac gttttggtat
   126181 agcgaccaaa gcgttctacc gtccattgat agccctgcgg cacgattttg acgcccgcgc
   126241 cgacaatgac cagcgcgaca aaaatgagaa tcgggataaa gataagcatc ggaaaaacct
   126301 cctgttgtac cgtccataat cagcaaaatt gctgcttgat taaacaaatt atacctgatt
   126361 actgaaagag agttccccct tattcctgcg aaggataaac tgtttttagt aaaaatcaga
   126421 aaaagggaac agcgatgcag gaaaatagtc ctttgcttca gctacaaaac gtaggatatc
   126481 tggcgggtga tacgaagatt cttaataaca tcaatttttc gctgcgtgct ggcgaattta
   126541 agttaattac cggtccttct ggttgtggca aaagtacact gctaaaaata gttgcttcat
   126601 tgatcagccc aaccagcgga acgttactgt ttgaaggtga ggatgtcagc acactaaagc
   126661 cagaaatcta ccgtcagcaa gtctcttact gcgcccagac gccgacgctg tttggcgata
   126721 cggtatacga taacctgatt tttccctggc agatccgtaa ccagcagcct gacccggcca
   126781 tttttctcga ttttcttgaa cgcttcgctt taccggacag cattttgacg aagaatatcg
   126841 ccgagctatc tggtggtgaa aaacaacgca tctcattgat tcgtaacctg caatttatgc
   126901 cgaaggtttt attgctcgac gaaatcacca gtgcgctgga tgaaagtaat aaacataacg
   126961 ttaatgagat gatccaccgt tatgtacgcg agcaaaatat tgctgtgctg tgggtgacac
   127021 acgataaaga cgaaattaat catgcggata aagtgattac actgcaaccg catgctggag
   127081 aaatgcagga agcacgctat gaactcgcat aatattacta acgaatcatt agcactggca
   127141 ttaatgctgg tggtggtggc aatcttaatt agccataaag aaaaactggc gctggagaaa
   127201 gatattctct ggagcgtcgg gcgcgcgata atccagctga ttattgtcgg ctatgtgctg
   127261 aagtatattt tcagcgtgga tgatgccagc ctgacattat tgatggtgtt atttatctgc
   127321 tttaatgcgg cgtggaacgc gcaaaaacgc agtaaatata ttgctaaagc ttttatctca
   127381 tcgtttattg ccattacggt cggggcggga attaccctgg cggtactgat cctctctggg
   127441 tcgattgaat ttatcccgat gcaggtgatc cctatcgccg ggatgatagc cggtaacgcc
   127501 atggtagcgg tggggttgtg ttacaacaat ttagggcaac gggtcattag cgaacagcaa
   127561 cagattcagg agaaactgag tcttggcgcg acgccgaaac aggcttcagc gatattgatt
   127621 cgcgacagta ttcgcgcggc tttaattccg acggtcgatt cagcaaaaac ggtaggctta
   127681 gtgagtttac caggaatgat gtccgggctg atatttgccg ggattgatcc ggtgaaggcg
   127741 attaaatatc agattatggt gacctttatg ctgctctcaa ccgccagctt gtcgaccatt
   127801 attgcctgct atttaaccta tcgtaagttt tacaattcgc gccaccaatt ggtggtgacg
   127861 caattgaaga agaaatgatg cgatgccgga tgcgtcttat cagacctaca tggcacctgc
   127921 aatgtattga attagcacgg tttggtaggc cggataaggc gttcacgccg catccggcgg
   127981 ctatgcgcgg atgcctgatg cgacgctggc gcgtcttatc aggcctacaa accagcacag
   128041 catcgcattt caacggaaaa tcaatacaac aacgcataca gctggcggcg atacttcgac
   128101 gccagtgcat cacccgtacc cagcgcagcg aggatctcct ggaatgtttt acgtgtctga
   128161 ccatctgcgg cggtgagatc tttacgcaga tgcccaaaca gtaactccag cgcctcttca
   128221 ttgcgcccaa cctggtgcag ttgcagtgcc agttgcgtcg ccagtgcggc atcttctgga
   128281 ttctccgcca cctgctgttg caactgttga atttccggcg tatcagccgc ctgcttcagc
   128341 agttcgattt gcgccaccag cccctgatag cgggtgtcct gatcctgcaa cggaatggtt
   128401 ttcagcacgg cttctgcatc ttcagaacgg ttcagcgcaa tcagcgtttc tgccaacagc
   128461 aggccgattt ccccgttctg attcgacaac tgccaggcgt ctttcagcaa tggcagggcg
   128521 tcggtgtaat tgccttcctg catcagttgc atcgcctgct gcgctttcag ctcttcttca
   128581 cgcggcagca ctttatccag cagggcgcgg atcgcctctt ccggttgcgg cccctggaag
   128641 ccgtctactg gttgcccgtt ctggaacaga tatacggtcg gaatcgcgcg cagaccaaac
   128701 tgggcggcaa tcatctgctc cgcgtcgcag tccagcttcg ccagaataaa ttgcccgttg
   128761 tactgcgccg cgaggctttc cagaattggg gttaactgca aacagtgctg gctacgttca
   128821 gaccaaaaat agaacagcac cggagtggtc atcgactgtt caagaacctg ttgcaggtta
   128881 gattcgttaa tgttgacaat attttctacg gacatggagt cgctctctgt tgtcgatatt
   128941 ttctttgaca tgggggctta agcgcgcgct tcaactcacc cctgcaatat tttgtccatc
   129001 acgcgccccg gcagcaggcg cttaagcacc attaccgccc tggtcaccag cgtcaccgga
   129061 tagcgcatct tcggcttctc gctaataaaa gcatggcgca ctttgccgac caccgcttcc
   129121 ggtcccaacg taaagcgggc ggcgatgcca ggattttcga ctggtttatc actttgcgtc
   129181 tggttgacgt tgtcggtgaa gcgagtacga atgggaccag gttcgatcag gctgacttta
   129241 attccgctgt ggcgcagctc catgcgcagt gcgtctgacc acgcctccag cgcatattta
   129301 ctggccgcgt aagcgccacg acccggtgtg gagattaatc ccatcaccga tgaggtcatc
   129361 acaatacgcc cttcacggtg cggcaacatc gcgggtaaca ggcgcatggt gagctggtgt
   129421 gcgccgaaaa agttagcgga aaactgctgt tccatctgcg cacggctgat ggtggaaagg
   129481 gggccataca tgccgaatcc ggcattgtta aagatcccat acagacaatt atcggtcagg
   129541 gcgatcactt cgtcggctgc gcgatcaaca ctttctggcg aatccagatc gatcaacacg
   129601 ccggtaaatc ccatgctgtt catgcgctca acatcatccg gtttccggca acctgccagc
   129661 acatgaaaac cctggcgttt taattcgagt gcgctttcca ggccaatacc actggaacat
   129721 ccggtaatta agaccgattt ttgcataact ttacctgtca ggatctccgt tgctttatga
   129781 gtcatgattt actaaaggct gcaactgctt cgccatccag tcggcaataa acggctgggc
   129841 gtcgcggttg ggatgaatac cgtcatcctg catccattgt ggcttgaggt agacctcttc
   129901 cataaaaaag ggcagcagcg gaacatcaaa ctctttggcg agtttggggt aaatggcgct
   129961 aaaggcttca ttataacggc gaccatagtt tgcaggcaga cgtatttgca ttaacaatgg
   130021 ttcagcgttg gcggctttga catcctgcaa aatctggcgc agcgtttgct cggtttgctg
   130081 tggctgaaaa ccacgcaaac cgtcattgcc gcccagttca accagcaccc agcgcggctg
   130141 atgctgtttc agcagagccg gaaggcgcgc cagcccttgt tgcgaggtgt caccgctgat
   130201 gctggcattg actaccgacg ttttactctg ccacttatca ttcaacaagg caggccaggc
   130261 cgcgctggca gacattcgat acccggcgct caggctatca cccagaatca ataacgtgtc
   130321 cgctgcggcg gcacggaagg ttaacaggac caggaacagg aagggcaaat gccagcggaa
   130381 aacattgttg aagttcatca tcttaagaag tccgtcggtc agggggagca tgaactctcc
   130441 atcctcaccg gagttgagct ggttgtcaaa cgtggcgaga ccatcgcact ggtgggcgag
   130501 tcgggatcgg gtaagtcaac cttgctggcg atcctcgccg ggctggatga cggcagcagt
   130561 ggcgaagtga gtctggtggg acaaccgcta cataatatgg acgaagaagc gcgggcaaag
   130621 ttgcgcgcga agcacgtagg ctttgttttt cagtcattta tgttaattcc tacccttaac
   130681 gcgctggaaa acgtcgagct tccggcgctg ctgcgcggtg agagtagcgc agaaagtcgt
   130741 aacggggcga aagcgttgct cgaacagtta gggctgggta aacgtcttga tcatcttccg
   130801 gcacagcttt ctggcggcga acagcaacga gtggcgctgg cgcgagcctt taatggtcga
   130861 cctgatgtgc tgtttgccga cgaacccacc ggtaaccttg accgccagac gggcgataaa
   130921 attgccgatc tgcttttttc cctcaaccgt gagcatggca ccacgttgat tatggtgacc
   130981 cacgacctgc aactggcggc acgctgtgac cgctgcttac ggctggtgaa cgggcagttg
   131041 caggaggaag catgattgca cgttggttct ggcgcgaatg gcgctcgccg tcgctattaa
   131101 ttgtctggct ggcgcttagc ctggcggtgg cctgcgtgct ggcgctgggc aatatcagcg
   131161 atcgcatgga gaagggctta agccagcaaa gccgtgagtt tatggcgggc gatcgggcgt
   131221 tgcgcagttc gcgcgaagtg ccgcaagcat ggctggagga agcgcaaaag cgcggcctga
   131281 aagttggcaa gcagctgact ttcgccacca tgacctttgc aggcgacacg ccgcaactgg
   131341 cgaacgtcaa agcggtggat gatatctacc cgatgtatgg cgatctgcaa actaatcccc
   131401 ctggcctgaa accgcaggcg ggcagcgtat tgctggcccc acgcctgatg gcactgctta
   131461 acctgaaaac gggcgatacc attgacgtgg gcgatgccac cttgcggatt gccggagaag
   131521 tgattcagga accggattcc ggttttaatc ctttccagat agccccacgc ctgatgatga
   131581 atctggcgga tgttgataaa accggagccg tgcagccggg gagtcgggtc acctggcgtt
   131641 ataaattcgg cggcagcgag aaccagctcg acggctatga gaaatggttg ttaccccagc
   131701 ttaaacccga acaacgctgg tacggtctgg aacaggacga aggcgcgctg gggcgatcga
   131761 tagaacgttc gcaacagttc ctgctgcttt cggcgcttct gaccttgctg ctggcggtgg
   131821 cggcggtcgc ggtggcgatg aatcattact gtcgcagtcg ctacgatctg gtggcgatcc
   131881 tcaagacgct gggggcaggg cgagcgcaac tgcgtaagtt aatcgtcggt cagtggttga
   131941 tggtgctggt actttcagcc gttaccggtg gggcgatagg cctgttgttc gaaaacgtgt
   132001 tgatggtgct gctcaagccc gttctgcctg ctgcactacc gccagccagc ctctggccgt
   132061 ggctgtgggc gctcggcacc atgacggtta tttcgctgct ggtggggcta cgaccatacc
   132121 gcctgttgtt ggcaacgcag cctttacgcg tattacgtaa tgatgtggta gcgaacgtct
   132181 ggccgctgaa gttttatctg ccgattgtca ccgtggtggt tgtgctactg ctcgccgggc
   132241 tgatgggcgg cagtatgctg ctctgggcgg tgctggcggg cgcggtagta ctggctttgc
   132301 tgtgcggtgt cctgggctgg atgctgctga atgtacttcg ccgcatgacg ctgaaatcgc
   132361 tacctctgcg cctggcggtt agccgcctgt tacgtcagcc gtgggcgacg ttgagccagc
   132421 tttcggcatt ttcgctctcc tttatgctgc tggcactgtt gctggtgttg cgtggcgatc
   132481 tgctcgaccg ctggcaacag cagctaccgc cagaaagtcc taactacttt ttaatcaaca
   132541 tcgctacgga acaggttacg ccgctgaaag cgtttctcgc ggaacatcag atagtcccgg
   132601 aatcgtttta tccggtggtg cgggcgcggt tgacggcgat taacgacaag ccgacagaag
   132661 gcaatggaga tgaggcgctc aaccgcgagc tgaatctcac ctggcaaaat acgcggcctg
   132721 atcataaccc gatcgtcgcc ggtaactggc cgccaaaagc cggtgaagtg tcgatggaag
   132781 aggggctggc gaaacgctta aacgttgccc tcggcgatac cgtgactttt atgggcgata
   132841 cccaggagtt ccgcgctaaa gtgaccagcc tgcgcaaagt ggactgggaa agtctgcggc
   132901 ctaatttcta ttttattttc ccggaagggg cattagacgg gcaaccgcag agctggctta
   132961 ccagtttccg ctgggagaat ggcaacggca tgttgacgca actcaaccgc cagttcccga
   133021 ccattagcct gttagacatt ggcgcgattt taaaacaggt cggtcaggtg ctggagcagg
   133081 taagtcgggc gctggaagtg atggtggtgc tggtcaccgc ctgcggtatg ttgctgttgc
   133141 tggcacaggt gcaggtggga atgcgtcagc gtcatcagga gctggtggtg tggcgcactc
   133201 tcggtgcggg caaaaaactg ctgcgcacga cattgtggtg tgagttcgcc atgctcgggt
   133261 ttgtatccgg cctggtggcc gcaattggtg cggaaacggc actggcggta ctgcaatcga
   133321 aagtgtttga tttcccgtgg gagccagact ggcgattgtg gattgtgctg ccgtgcagcg
   133381 gtgcgctact gctgtcgctt tgcggcggct ggctgggtgc gcgactgctt aagggtaagg
   133441 cgctattcag gcagtttgtg gggtgatgtg ataaagccgt ttatttctac ctggtagata
   133501 aacggcttta ttattagtgc atcacgtaat taaaaaaatg ttatgcccaa acatataatt
   133561 aatatacatt actaaatgag atgtttatta agtttatatt atataattaa aatctatgaa
   133621 atgggtataa tcatatgggt gacattatat atttacgcat tacaggggag caacaagggg
   133681 atatttctgc aggatgcggg acgcaagtct ctgtcgggaa tcggtatcaa cagggacatg
   133741 aggatgaaat atttgttttt agttttcagg gaggagtaag taacacagga tttggcatta
   133801 atcatcaagc gatacaattt tgtaaaattc tcgataaaag ctcaccgctg ctgatgaatt
   133861 gc
//
LOCUS       DAFGPF010000002       126465 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFGPF010000002 DAFGPF010000000
VERSION     DAFGPF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 126465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 126465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..126465
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.002"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..590)
                     /gene="upp"
                     /locus_tag="LSX49_000130"
     CDS             complement(<1..590)
                     /gene="upp"
                     /locus_tag="LSX49_000130"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBL7166603.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGL"
     gene            915..1952
                     /gene="purM"
                     /locus_tag="LSX49_000131"
     CDS             915..1952
                     /gene="purM"
                     /locus_tag="LSX49_000131"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBL7166604.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLKLIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            1952..2590
                     /gene="purN"
                     /locus_tag="LSX49_000132"
     CDS             1952..2590
                     /gene="purN"
                     /locus_tag="LSX49_000132"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBL7166605.1"
                     /translation="MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLE
                     RARQAGIATHTLITSAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     TEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
     gene            2762..4828
                     /gene="ppk1"
                     /locus_tag="LSX49_000133"
     CDS             2762..4828
                     /gene="ppk1"
                     /locus_tag="LSX49_000133"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HBL7166606.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQSE"
     gene            4833..6374
                     /gene="ppx"
                     /locus_tag="LSX49_000134"
     CDS             4833..6374
                     /gene="ppx"
                     /locus_tag="LSX49_000134"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HBL7166607.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(6413..8656)
                     /gene="pdeF"
                     /locus_tag="LSX49_000135"
     CDS             complement(6413..8656)
                     /gene="pdeF"
                     /locus_tag="LSX49_000135"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HBL7166608.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGIALGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDSRLISQRLFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFAI
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLHIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRS
                     PVNHIYLLLGELNTVAELSIVTNVPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELISPDSFLPVAHEFGLSSSIDMWVIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLAKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMRVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
     gene            complement(8838..8990)
                     /locus_tag="LSX49_000136"
     CDS             complement(8838..8990)
                     /locus_tag="LSX49_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166609.1"
                     /translation="MSHAVDGTYIKAQQDKMVNSSLCKEASVNTYFNVMEVNLIIYND
                     DVIMMS"
     gene            9008..9199
                     /locus_tag="LSX49_000137"
     CDS             9008..9199
                     /locus_tag="LSX49_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HBL7166610.1"
                     /translation="MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHH
                     QSKKEAQQSTLSVESPVQR"
     gene            9501..10019
                     /locus_tag="LSX49_000138"
     CDS             9501..10019
                     /locus_tag="LSX49_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HBL7166611.1"
                     /translation="MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNAQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
     gene            10035..10574
                     /locus_tag="LSX49_000139"
     CDS             10035..10574
                     /locus_tag="LSX49_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HBL7166612.1"
                     /translation="MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQRQH
                     DEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATADKKRDQSYE
                     DELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSDSWFN"
     gene            complement(10769..11266)
                     /locus_tag="LSX49_000140"
     CDS             complement(10769..11266)
                     /locus_tag="LSX49_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 family protein"
                     /protein_id="HBL7166613.1"
                     /translation="MIWAFAKAYRKQLVVMAMLAVLVISGVVAWNVHGSRQYDAGYAQ
                     AKEDQKQADDKLRSQREQEKTQIEREAQSRIDAARADAEYANSAADSMRAELDKTRRL
                     AEHYTGSFPPGTPASKVIGVLADMLEESNRVYNATAAEAEKYRIAGEFCEQQYDSLKK
                     QKSWH"
     gene            complement(11263..11892)
                     /locus_tag="LSX49_000141"
     CDS             complement(11263..11892)
                     /locus_tag="LSX49_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 19 protein"
                     /protein_id="HBL7166614.1"
                     /translation="MEIKQFQRAAGISEALAARWFSHITSAMKEFGIRKPEDQAMFIA
                     QVGHESGGFTRLQENFNYSVTGLANFVRAGRLTQGQANALGRRAGEPPLPPERQRAIA
                     NLVYSKRMGNNASGDGWNYRGRGLIQITGLNNYRDCGNGLKVDLLENPELLAQDEYAA
                     RSAAWFFSSKGCMKYTGDIARVTLIINGGRNGIDDRRVRYITASKVLAV"
     gene            complement(11882..12190)
                     /locus_tag="LSX49_000142"
     CDS             complement(11882..12190)
                     /locus_tag="LSX49_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL7166615.1"
                     /translation="MVTNELVLLITNAIICTGIAIRVVTFRRNGSQHRRWGGWLAYFL
                     IVAAASIPVRVAYAIWLRTPMAVDLSEVIINAVMLAAVIKTRGNVVQIFKTSRSKHGD
                     "
     gene            complement(12180..12581)
                     /locus_tag="LSX49_000143"
     CDS             complement(12180..12581)
                     /locus_tag="LSX49_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166616.1"
                     /translation="MNGTVTADSLNQGLSLGALASVVYGVPPEVALGALAGAVIFVTS
                     AVEYPVRRRVLLSILSFLCGLLFYKPTTSILIGIASMIPTITQDSFEKGIVFSAGAFV
                     SAIVAVRIGIWLYHRSDNPRQLIPGRKGDGN"
     gene            complement(12679..15330)
                     /locus_tag="LSX49_000144"
     CDS             complement(12679..15330)
                     /locus_tag="LSX49_000144"
                     /inference="COORDINATES: protein motif:HMM:NF025253.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HBL7166617.1"
                     /translation="MTVSTEVDHNEYTGNGATTSFPYTFRIFKKSDLVVQVSDLNGNV
                     TELVLDTDYTVTNAGGYNGGNVILSKALANGYHISISRELPVTQDTDLRNQGKFFAEV
                     HEDAFDKLTMLIQKCFSWMRLALIKPSILANYYDAKNNKISNLANATDRNDAVNKGYV
                     DDLFTGGVTPTPNSAKNDIFTNHQRKIVATMPLLFPEYDAIMAANPSATYMYPQGFCV
                     SEDLIYITYPFEPKQTNNVVAVFNISGIYQGYFYVQAGGPGFAAEGIVVTSDYGPKKM
                     FVGHTNGILREFNMEGALYGSNLPLVQNHDVGLFNQFSYRRGIWLVEQNAPEVGQKIT
                     RTVLAVFDSGFNRLSTITLPLHDVGYVTKSTSPYAPYFNKRQGIAVGDNYFVCGYGGF
                     IADGAGSAGYNEYQGSKVFNPDGTKRTESMLHPQAMMDLMKAAGLNVTRIENEGVCVS
                     QDGKSIYSLYIHQERTGSEPYNSGLVIFEDFSTDKDAIDFTPASRLYRGFDIDHASIG
                     VYPRSAKGIVNPVDGTLFTNMTEILRYMQEMSQKAFNFYTGTVSIADISGVAIPSSTY
                     VEILNANNQTFIVNYYSSDSGISYLVATNPSGDFVFVRQRPAQWASNLTIQQNADPDT
                     NQLNRITASSYAGATTNSQKILVLDQQATASANSLVLGGSSSVFRSATTVDIACNSDP
                     TALGGTIRWRFYDTGLRPFADNTYNFGQASFRIKDAYFANAPTVSSDATLKTNPEAIS
                     DLSEMLSSDRDSILDAWGDISVVAYRWLDAISMKGDGARWHFGVMAQQVRDVFLAHGI
                     DGTRFGLLCYDEWDDIFEPVIATKEITDTSGELVTVEYDTGEQRLVKKAGSSWGIRPD
                     QCAWLEAAYQRRRCDRIEERLELLESK"
     gene            15526..15783
                     /locus_tag="LSX49_000145"
     CDS             15526..15783
                     /locus_tag="LSX49_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166618.1"
                     /translation="MQQYHYPLEDGFTERIHTPGGVRSLVEGSHLMKLLRDLDKDGFN
                     VDGPLAELTALINYVTSSQMSMQDLQTHLDYCAEQLRKQTT"
     gene            complement(15807..16313)
                     /locus_tag="LSX49_000146"
     CDS             complement(15807..16313)
                     /locus_tag="LSX49_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafO family
                     toxin"
                     /protein_id="HBL7166619.1"
                     /translation="MPNKFQGLVHPGIFGKDPELIPIKNAFIDHWRYGHHKDFGKDTL
                     FRDPPKEMLEYHIRHVHLNIGNYTDKFGESGTEQCWKNWASGKKDKTTNKHKKIPTSD
                     VYVIYLVTSERHAFLLDYWDEPAHKTVEIDEQKQKLVVECDRILRLKKLESMPRDASL
                     WDPEFYDC"
     gene            complement(16303..16806)
                     /locus_tag="LSX49_000147"
     CDS             complement(16303..16806)
                     /locus_tag="LSX49_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166620.1"
                     /translation="MRHRRFALKRPEKEKEQEMVIEAAAYAAAMATADAIRNYEEEDN
                     KNSYRIYLYESRHSVTDHEACLKKQGEVFHCNLAEYIRNEMERNLALSHFGYKSQESG
                     FAGFKDKINERWQRLYKPLQVDEKTHQLVMHEVPKMSVEKSHAISRRMFARTAEDMAQ
                     ELYDDAE"
     gene            17252..17947
                     /locus_tag="LSX49_000148"
     CDS             17252..17947
                     /locus_tag="LSX49_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HBL7166621.1"
                     /translation="MTATKSTSIFSFESQADIRVIVINGEPWFIASDVCRAIGIANHR
                     DAVRKLDDDEKGVASTDTPGGEQESIIISESGLYTLILRCRDAVTPGTIPYRFRKWVT
                     GEVLPQIRRTGSYIKNSLPQEERIKMVADQVANATASAVMQAMKIENKTYSAPLKPGY
                     RSLIHSPSGVLGLTENSLLMNLLNQLQEDGHDVSGAAAELTTMFCYIVGVSKCLRDIQ
                     THAEYINDKAGFF"
     gene            18071..18397
                     /locus_tag="LSX49_000149"
     CDS             18071..18397
                     /locus_tag="LSX49_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166622.1"
                     /translation="MTKLGFVMRGPVRSGTHAKRSKSRIFTGKVVARKSAIGSFNSEN
                     AALRHIFISTKPRASADVHTMSIPITKNIKRIKKLSSAESKEISFRQLNSLETHMKEE
                     EFDVFE"
     gene            18384..18896
                     /locus_tag="LSX49_000150"
     CDS             18384..18896
                     /locus_tag="LSX49_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafO family
                     toxin"
                     /protein_id="HBL7166623.1"
                     /translation="MFLSEYSGKVIPTGEFKTDDFLISLKDAFKQHWRHGHHPDLGKD
                     TLFERPDEVLGFHLRKVHVNIGEYASYSYSCTEQCWDEWSYGLIDEQGNYRPKPTSNA
                     YLIYAVNEIRDAALLAYWDPPAHTKANAKVWMDSVLNFTKLFHERTNTAPLSRNVYPW
                     DYSYKSKKPA"
     gene            18978..19139
                     /locus_tag="LSX49_000151"
     CDS             18978..19139
                     /locus_tag="LSX49_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane anchored protein"
                     /protein_id="HBL7166624.1"
                     /translation="MKKAFAALFVLLSLVASTQAFAGRCQHDSDTAADGSRCGGRSAD
                     SRPGGGGIR"
     gene            complement(19171..19587)
                     /locus_tag="LSX49_000152"
     CDS             complement(19171..19587)
                     /locus_tag="LSX49_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001337645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166625.1"
                     /translation="MDWCCFSMIGVIMRKVFLIFGFMLLVGCQSAAQFERNMLTWRGQ
                     SIDAMVQQWGYPQGELTSPDGNRVYVYSSSDSYNVPQTTTYNTTSNLIGNTIYSNTYA
                     TTDGGYTLHFSCSVYVEFGADKIIKNVTWRGNNCVA"
     gene            complement(19771..22245)
                     /locus_tag="LSX49_000153"
     CDS             complement(19771..22245)
                     /locus_tag="LSX49_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166626.1"
                     /translation="MRQECIQAVQQAAQRTLTAREIQNIEDRIYRNMRSIARDDPMSW
                     RQLSESERLYRAAQLASEELQREAALKKRRVALTIAARQRLDKFINSYQGADGKLGAL
                     NRTIAFNADGKSNFLSVESRTKATRDYALSQLQEAFEAVDPRFFGLFEDEAGVRDLVY
                     EMRGQNTGNAKARKGAKAWREVTELLRRRFNDAGGDIGYLENWGIPQHHSMEKVGAVS
                     KDKWVGDVIGKLDRKYYTRADGQLMNDAELSAFLGEAYNTIATGGLNKLTDTGMRISG
                     ARANRGNASRQIHFKDADSYLQYQQLYGDRSLWEIMVGHLEGISKDIALVETYGPNPD
                     HVFRSLLDQVKAETATANPSKTGKVERLANNTENLYNFISGKTQPVANPHIARWSDNI
                     RNWLVASRLGSALLSSFSDLGTMYLSAKVTNLPMNQLFRNQLEAMDPTNRTELARARR
                     AGLAMESLLGSVNRWAMDNMGPSVSRWAATAVMRASGLTAWSDAHKRAYGVTMMGSLG
                     EVVSRTPDLRSLDDSDFRILKSKGITDTDWSVWKLAQQEDWGNGNNTMLTPESIMRIP
                     DSAVKHLGEPERVKFEAMRKLLGAVTEEVDMAVITPGAREQLITGSGIQRGTWKGELT
                     RSVFLFKSFPISVVMRHWHRAMGMSSAGGRAAYIATFLASTTMLGALSMQITDLINGR
                     NPKEMTGDHMVKFWINAFLKGGGAGLYGDFLFSDHTRYGSGALASMLGPVAGLVDDVV
                     KIAQGIPLNAVEGKNEQTGGDLVKLGKGLMPGANLWYLKAALDHMIFNQMQEYFSPGY
                     LRKMEQRSKKEFNQTYWWRPQDVTPQ"
     gene            complement(22251..24053)
                     /locus_tag="LSX49_000154"
     CDS             complement(22251..24053)
                     /locus_tag="LSX49_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166627.1"
                     /translation="MSYFGLNPVNQNQQLDEAASNPAGFNSDVGFFDNAVGAALSGLY
                     SGLVAKPDQLLWAGMDKIVSPIAQFVNENTSLNDTSVSYIAEQRKLAEQQVKRLTPDA
                     ATTGTAGQVLYGLFDMGGQAVVGTTLGGPVGGAAAVTSLQGFSEFERLTAQGVDFRTA
                     QEAGLVQGITAGAGTLIPMSLGLRAGGALAEGVAAQLARTGESSVRRAAATAVRATPD
                     IAYAAGTNIAFGMAQRGLTAKTLRDGGYSEMANQYDVLDRQAIAIDAVLGVAFGGVGR
                     FINSRGESTSAPNFSQVDVDAALAANAAHHAEIDIAPGVPINVLSRNSHIQALRKAMS
                     DVSQGRPVDVASIVESASFSEIPGRKSLLSQAVNEALSSVDDGVTARSIENRLLEEQA
                     AQLLPRGDRQVYQSEIANSQRIIENLTEQRAQILAEDPTGSGKALSRARSDKQARLRD
                     IDQRIRQAQERLEFSRNALAPHEPGGQFFEARAELARRQQAESELNAQAVSFYKTAEV
                     RTPDEVAPFEPDKILQQAEQKMMADQAGDIDLRIAEDSLLESPDMIITVLDDDGNPQS
                     RSAREVLDEANRESEQAIQDSSLFDVAVACFLRG"
     gene            complement(24050..26563)
                     /locus_tag="LSX49_000155"
     CDS             complement(24050..26563)
                     /locus_tag="LSX49_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166628.1"
                     /translation="MPVVPTTSGRQVQSRGISTQGFSSFQTPNVGDVLGDVAEQYAGI
                     IAQAKQRANVAMAQDASLSLSQISSDLLNNPETGLLNLKGKNAIGKGQEYTQQFDAQV
                     EQLAMSLPDEQARNAFMQQAQQQRIQFTTQAGRHEIGQINAYEEGQFQATLLNNGKNA
                     AALYGDNAAYVLANKQTFQQIEDYGIAHGWSDEQIQAKKIEFKEKVADAALSQWSANN
                     ATAFIQSNGELSDTAAGASRAVADSDSSERARGIRNNNPGNLEYSKTNPWVGQTGDDG
                     RFAKFETPEHGIRALGRNLMSYQRQGIDTVSEIINRWAPPTDKNDTMSYIKAVCEQLG
                     VSADEPLDASNPDTLKALCAAIIHHENGSQPYSDQLLSAGVSAALGLSTIPTNTKRYT
                     GNAAFDAASPEAQASFMRQADQLRRQQQAEYKTMIDSQVRDATAAYMRGVEFPNPPGE
                     ADFIAAYGVREGNLRYTEFRNTQIAGQYIGSFRNMPTSSITAYVEQLRPDTGETGEGY
                     AARAALYDNVVSAASQVIKQRQADPVQFSLAAGQAKPIDMSNKDNFGQSVALRAAQVS
                     DLAKSYGTPLTFFSKDEANQIGVFFRDAPVSQQAAYLDTIRQSTGGGQVYMSALQQIS
                     ANAPSAAVAGILMDKPGGILAEKNWFNPDVSVSPETAAQTILAGAAARKGTDDAKGIP
                     MPKDADLRLEFSDMVKDAFAGDAQGASMAYEIAKDYYAGVMAKKGVVSGEIDNDIWKQ
                     AVNVATGGVHDYNGMGNVLLPWGMSAEQFDKQVNQVWNEQVVGTGIKTPPGQYGLQSY
                     GDSQYLVKLGTGYLLKDDGSPVVLDLTQKRQRFSGDIPQ"
     gene            complement(26576..27115)
                     /locus_tag="LSX49_000156"
     CDS             complement(26576..27115)
                     /locus_tag="LSX49_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166629.1"
                     /translation="MCNPAIALVAVTVASTAASMYSQSKQAKYQSAIADRNAEIAEAQ
                     AQDSINRGNIEADQRRREMRQRSGTAAATMGATGAELSSGTALDVFADNAQFGALDAL
                     TTVNNAQREAYGYQVQGMNAQAQGAAAQSAAKSSMTSTLLTAPLKAYGAYQMGGGTWS
                     PFSQKAAPISAAVGTPTGR"
     gene            complement(27115..27579)
                     /locus_tag="LSX49_000157"
     CDS             complement(27115..27579)
                     /locus_tag="LSX49_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166630.1"
                     /translation="MIDVQIIPATEEHLQMILPDVRQADIDELYAVSLMTTEDALRVG
                     LRTATMAWSGFANGELVTMFGVSPASMIGGNGTPWLVGTSRIEKYQKTFLRHCRPVLQ
                     QMLAVYPRLENYVDERNHVAKAWLHWLGFRLEEAAPYGALGLNFHRFHMERK"
     gene            complement(27579..30056)
                     /locus_tag="LSX49_000158"
     CDS             complement(27579..30056)
                     /locus_tag="LSX49_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166631.1"
                     /translation="MAISWIQPSFAGGEIGPSLYGRIDMAKYQVALRKCDNFIVRQYG
                     GVENRPGTRFVGAAKYPNRKCRLIPFQFSTVQTYALEFGHQYMRVIKDGALVLNSSNV
                     IYEIATPYTEADLFRIKFTQSADVLTLVHPAYPPKELRRYAHDNWQLVDVVTKNGPFE
                     DINIDESVTVYASASTGTITLTASASIFGAEQVGKLFYLEQPAVDSVPVWETSKSTSI
                     GDIRRADSNYYRAVTVGKTGTLRPSHTEGTSWDGWGGSGDDDTGIEWEYLHSGFGIAR
                     ISAANGTTATAEVISYIPSQVVGEDNASYKWAKYAWNSVNGYPGTVVYYQQRLYFAAS
                     TAFPQTIWASRTGDYKDFGKSNPTQDDDRIIYTYAGRQVNEIRHLIDVGSLVALTSGG
                     EYVITGDQNKVLTPSSFAFSSQGSNGSSNVPPIAVANIALFVQEKGSVVRDLAYSFDV
                     DGYQGNDLTILANHLFQKHSIVDWCFSIVPYSSAFCIRDDGKLLVMTYLRDQQVFAWA
                     PQSSTGKYESTCSISEGNEDAVYFVVNRTVNGQTVRYIERLSSRLFTSDEDAFFVDSG
                     LSYDGRNTSDRTMIITGGSGEWDYREEYTISVSGGAYFTSSDIGAQLQFPFPYTGTDP
                     DTGDEVSKELRCDIISVTSNTAVVVRANRNVPPSLRNVATTNWQMARRTFGGLSHLEG
                     QTVNILSDANVEPQKVVSGGAVTLESPGAVVHIGLPITAEFETLDININGQETLLDKK
                     QVIPSVTLVVNASRGIWATTPGGKWYEYPQREFEFYDDPVDDATGKVEVKLDSNWGKN
                     GRVKIRQLDPLPLSVLAVIPRLTVGGF"
     gene            complement(30056..30661)
                     /locus_tag="LSX49_000159"
     CDS             complement(30056..30661)
                     /locus_tag="LSX49_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166632.1"
                     /translation="MASVVEICNRALSNIGNSRSINSLTEASKEAGECSLHFEACRDA
                     VLSDFDWNFATKRVALADTSNPPPDWEYAYQYPSDCLRITEIMLPGVRNPTAAMRVQY
                     EVGADTNGTGKLIYTDQPQAWLKYVSRVSDVNMFDAIFMEALAWRLAAAINMALTGNA
                     DLGTFALNMYNRVILSAGSHSQNESQEPQPPVDEFTIARLS"
     gene            complement(30718..31053)
                     /locus_tag="LSX49_000160"
     CDS             complement(30718..31053)
                     /locus_tag="LSX49_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166633.1"
                     /translation="MSGEKPRYRVLRLSHIHNTLWPEGAEIEYEGEPGSALEPVNDAA
                     RQAKAKVAGKVSMAATSTKIINDVSDDGELDKLREEYELLFNEKPHHNAKAETLREKI
                     ADKRKELGV"
     gene            complement(31064..31501)
                     /locus_tag="LSX49_000161"
     CDS             complement(31064..31501)
                     /locus_tag="LSX49_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166634.1"
                     /translation="MITDKLLMFSEAQAVTNTAASTDVIDLGPIDGKRRDIGVGYPLE
                     FWALVNAAAAASGDATVNIQLQTSENNSSWTTIYDSGALAKTALTAGKRVVSAKVPAG
                     VQRYLRVNYSVATGPLTAGKFTAGISLDVDANTPYPIRSKVTG"
     gene            complement(31553..32539)
                     /locus_tag="LSX49_000162"
     CDS             complement(31553..32539)
                     /locus_tag="LSX49_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166635.1"
                     /translation="MAVKGLTALTLADWGKRVDPNGKVDKIIELLGQTNPILQDMPFV
                     EGNLPTGHRTTIRSGLPSATWRLLNYGVQPSKSTTVQVTDSVGMLETYAEVDKSLADL
                     NGNTAEFRLSEDRAFIEAMNQQMAQTLFYGDSSVNPQQFMGLSSRYSSLSAGNAQNII
                     DAGGTGTDNTSIWLVVWGENTVHGIFPKGQKAGIQMEDKGQVTLEDANGGKYEGYRTH
                     YKWDNGLALRDWRYVVRIANIDVSNLSEPSSAANIAKLMVKALHRIPNRGMGRPVFYM
                     NRTVGQALDLQSLEKTSLAISVKETEGEWWTSFRGVPIRETDALLETEARVV"
     gene            complement(32554..33249)
                     /locus_tag="LSX49_000163"
     CDS             complement(32554..33249)
                     /locus_tag="LSX49_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL7166636.1"
                     /translation="MNLFERLLYSRLCNEQPVDGGAAPAASEPSAPAGDNPAPVGDPS
                     QQEGDKPQPVADGDKPADDKKPENDKQDEKKDGDKPEGAPEKYEFQAAEGVELDTEAL
                     KEFEPVARELNLTNEQAQKLVDAYPKILAGVQQRQAEAWQKTTEQWAADVKADKEIGG
                     DKLISNLSAAQRALDQFGTPELKEYLNTTGLGNHPDLVKTFVKIGKAMSEDGMVTGGN
                     EGQRSAAEVLYGK"
     gene            complement(33252..33548)
                     /locus_tag="LSX49_000164"
     CDS             complement(33252..33548)
                     /locus_tag="LSX49_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166637.1"
                     /translation="MTDYEDDQLKEENARKQRDMAQREIDDIRFVMSSEQGRRVVWSV
                     LEKGRVFSAISPMDAMAMAFNEGQRNLALELFQRVMAHCPEQYLKMAKEASEQE"
     gene            complement(33545..35224)
                     /locus_tag="LSX49_000165"
     CDS             complement(33545..35224)
                     /locus_tag="LSX49_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7166638.1"
                     /translation="MAETTKERLNKQFAQLESERQSFEPHWRELSDYINPRGSRFLTS
                     EANRNDRRNTRIIDSTGTMAARTLASGMMSGITSPARPWFRLATPDPEMMDYGPVKLW
                     LEAVQNRMNDMFNKSNLYQSLPQLYGSLGTYSTGAMAVLEDDEDIIRTMPFPIGSYYL
                     ANSPRGSVDTCFRKFSMTVRQLVQEFGLNNVSESVKSMWESGTYEKWIEVMHSVYPNI
                     DRDTSKLDSKNKPFKSVYYEVGGDNDKLLRESGFDEFPIMAPRWEVNGEDVYGSSCPG
                     MLALGPVKALQLLQKRKSQLIDKATNPPMVAPTSLKNQRASLLPGDITYIDQITGQDG
                     FRPAYLVNPSTADLVADIQDTRQIINSAYFVDLFMMLQNINTRSMPVEAVIEMKEEKL
                     LMLGPVLERLNDECLNPLIDRAFSMMVRKNMLPPPPDAMEGMPLKVEYISVMAQAQKS
                     IGLSSLASTVNFIGQLAQAKPEALDKLNVDQAIDAFADMSGVSPTVIVPQEQVEQARQ
                     QRAQQQQQQQMMAMGMAAAQGAKTLSEAKTSDPSVLSAMANAVSGQGGQSQ"
     gene            complement(35239..35445)
                     /locus_tag="LSX49_000166"
     CDS             complement(35239..35445)
                     /locus_tag="LSX49_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166639.1"
                     /translation="MCMGSSPSVPATPEVQAAPQEQDAAVVDARDEETRRRRAAAGRS
                     STLLTGSQGDTSTANTSGKTLLGQ"
     gene            35873..35949
                     /locus_tag="LSX49_000167"
     tRNA            35873..35949
                     /locus_tag="LSX49_000167"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35907..35909,aa:Arg,seq:tct)
     gene            36148..36555
                     /locus_tag="LSX49_000168"
     CDS             36148..36555
                     /locus_tag="LSX49_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001595512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166640.1"
                     /translation="MNDQQIEKEIVEKGKTAPRVTPEKIEGLICSEHFFTAAQGDHQA
                     KEDDLIYNPEPYVEATPDALHLLTFCVLVLKNGFTVTGESACASPENFDAEIGRKIAR
                     QNAVNKIWMLEGYLLKQKLSEQQHSDMSQTASR"
     gene            complement(36613..38088)
                     /locus_tag="LSX49_000169"
     CDS             complement(36613..38088)
                     /locus_tag="LSX49_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBL7166641.1"
                     /translation="MTDTALSPEEQLIEDIAGFTHDPLGYALYAFPWGEDGTELAHAT
                     GPRQWQADAFREIRDHLQNPETRYQPLMLARASGHGIGKSAFISMLINWGMSTCEDCK
                     VVVTANTDNQLRTKTWPEIIKWSNLAITKDWFTCTATAMYSNDPGHDKRWRADAIPWS
                     EHNTEAFAGLHNERKRIIVVFDEASNIADLVWEVAEGALTDEDTEIIWVAFGNPTRNT
                     GRFRECFRKYKHRWKTAQIDSRTVEGTNKQQLQKWVDDYGEDSDFVKIRVRGIFPDAS
                     ELQFIPTGLTDEAMKRVVTAAQVAHAPVIIGVDPAYSGVDDAVIYLRQGLHSKVLWTG
                     NKTTDDLIMAKRIADFEDQYQADAVFIDFGYGTGLKSIGDGWGRTWQLVPFGGASTDP
                     QMLNKRGEMFNSCKTWLRLGGMLDDQETADDLSAAEYKVRVDGKIVIEPKEDIKERLG
                     RSPGKGDALLLTFAFPVSKRLRLPWQQNQQGKAITDYDPYA"
     gene            complement(38085..38717)
                     /locus_tag="LSX49_000170"
     CDS             complement(38085..38717)
                     /locus_tag="LSX49_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBL7166642.1"
                     /translation="MMPAEPKTYKRKSTQFKPLTAMQEAYCQSYIKTPENQTQAAINA
                     GFSPNTAAVKASVMMRDERIQKRIAELMEERNKRMRVSADYVLMRLVEIDQMDVLDIL
                     NDDGGMKPIAEWPKVWRTSLSAMDIATIKTTQASLQKENGEADLSVEDVEHILKKVKW
                     PDKVKNLELIGKHVDVNAFKERLDVNVNVTIADRIAAARKRLKERQDGNQ"
     gene            complement(38792..39004)
                     /locus_tag="LSX49_000171"
     CDS             complement(38792..39004)
                     /locus_tag="LSX49_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166643.1"
                     /translation="MPKIRYDLEDMRDNSANFPKEVKFLMNKYGCARRDIVIDSQHPC
                     GEDVIFIRGKWEWYLDESFYDEFDGL"
     gene            complement(39022..39360)
                     /locus_tag="LSX49_000172"
     CDS             complement(39022..39360)
                     /locus_tag="LSX49_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166644.1"
                     /translation="MAKSAAERKAAQRARQAASGVRKLEIVLDAQEIEMLERNCATRR
                     PGRAPYEFGEYIALLIRQDDARVRGRIKSISRKRCGKCGERVPVNSCPCNGDSQCWVT
                     KGWHETKLIV"
     gene            complement(39396..39638)
                     /locus_tag="LSX49_000173"
     CDS             complement(39396..39638)
                     /locus_tag="LSX49_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HBL7166645.1"
                     /translation="MFSLIQRGQIYTDSAGYPVKIIRSTDHSVFFKRMDGYPGRVCIR
                     KFNNLFEHIDHREYHQILAETEQENHLKKLRAMQRR"
     gene            complement(39705..40241)
                     /locus_tag="LSX49_000174"
     CDS             complement(39705..40241)
                     /locus_tag="LSX49_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="HBL7166646.1"
                     /translation="MITITNKKQYPGEQYLNELITNIEFAARAPVEVVRAMAAELQKR
                     READSAEPASNHEELPLDYLQGQKDGLEWAAQLAEANHPQTGDWLYDDPLELAKAIRK
                     GPDMPEFDGPTPVTPDGWISCSERMPAQDDWILIYSKHGEYMAGQVQGEYVELSDGTL
                     SWLGNALFWMPLPEPPQG"
     gene            complement(40238..40570)
                     /locus_tag="LSX49_000175"
     CDS             complement(40238..40570)
                     /locus_tag="LSX49_000175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166647.1"
                     /translation="MADRKKRFRKNPSLGMGDWRFFISEPGIISVEDLPPGWGLLHVV
                     NGRVRKVHGWPKGNCCWGNPEDKPFIGNKQVECDYMLSALRRMELRGHLNEIYDGVIV
                     NKKEGNAA"
     gene            complement(40575..40753)
                     /locus_tag="LSX49_000176"
                     /pseudo
     CDS             complement(40575..40753)
                     /locus_tag="LSX49_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_305741.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(40755..41162)
                     /locus_tag="LSX49_000177"
     CDS             complement(40755..41162)
                     /locus_tag="LSX49_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
                     /protein_id="HBL7166648.1"
                     /translation="MNKIDYQALREKAEKAGEDKWQAKKINGDFFVIRHGSYTRQHGY
                     TSYQPIAEIDCKPVRDFVAKANPATVLELLDELEAAKKRIAELEAREILLPERSSMLH
                     RTDFHDDYQTVMAYKVSEVINAIRATGIRIKGE"
     gene            complement(41159..41383)
                     /locus_tag="LSX49_000178"
     CDS             complement(41159..41383)
                     /locus_tag="LSX49_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166649.1"
                     /translation="MSGKRMTNRELVDAAIKLAGDFYSMMGYTHRPGFKYWESPHPQE
                     QLVFQMACRAFEVIRGSDVMDAVADLEDEE"
     gene            complement(41380..41817)
                     /locus_tag="LSX49_000179"
     CDS             complement(41380..41817)
                     /locus_tag="LSX49_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166650.1"
                     /translation="MESNIKGLVSAGHEMASELKAECGAVDMRSVAKLISDLATQLEV
                     QLVRANALAAENALARKAVQAFCDVVGDSTEVICEEIGRDGVLVILEAMKATGNMPAT
                     DAFLSEVRAQGVEMMREHPSIKLCSLTHICDELAAQLRKGGNQ"
     gene            complement(42484..42837)
                     /locus_tag="LSX49_000180"
     CDS             complement(42484..42837)
                     /locus_tag="LSX49_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL7166651.1"
                     /translation="MRKQIQALGRLKTGQMNKTESAYCQHLELRKRAGEIAWYRFEGI
                     KLRLADNCFLTVDFAVMLADGQLVMVDVKGSKSVFTDDARVKMKVAADSYPFVFQVAY
                     PKPKKLGGGWEVEEL"
     gene            complement(42955..43740)
                     /locus_tag="LSX49_000181"
     CDS             complement(42955..43740)
                     /locus_tag="LSX49_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL7166652.1"
                     /translation="MNNVFTAIQNRDGEALSRMSGYEHQYVNNDNVVNMSAERLVDAL
                     FKQLKQLFPAAVVTNLKTPEQEVAAKQQWIAAFAEGGIRTREQVSAGMRHARASESPF
                     WPSPGQFIKWCKDSKMVLGVTIDDVMAEFHRYSKEKSLYPGGPERFPWRHPVMYWVVC
                     DTRRAMYQRQLSEIEVEKHARRLLDDWAKKVASGQQIPDPVISIQAKPEPMSTPPDTG
                     RDVYHPPGRSFGCMPNAATLGGMAPAQWLMEEYRRGKAAGFIK"
     gene            complement(43737..44495)
                     /locus_tag="LSX49_000182"
     CDS             complement(43737..44495)
                     /locus_tag="LSX49_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7166653.1"
                     /translation="MSRHATDWAWETDPGSSSLKLILLSMADRADEYNLCYPSIERLV
                     KDTCLNKKTVQAGLISLMKMGIISDTGERKGATKRVRVFSLNIPKNGMLNDPKNGMLN
                     DPKNGMLNDPKNGIQNQSYNQSFNQERESRTKSGDSVPHDPGANNAVMNNFVPPGGPG
                     QLGKFVMHEQWQPSDDFLRKSSLQGIYLDSLPTAQELAEFRIYWMAEGKAYHQAQWEQ
                     KLARRLQISRQKQSTLPDNNVPHWNSPEAWEDFL"
     gene            complement(44511..44711)
                     /locus_tag="LSX49_000183"
     CDS             complement(44511..44711)
                     /locus_tag="LSX49_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166654.1"
                     /translation="MEIITRIDAAKRGLKRYYTGKPCKHGHDSERWVYNGHCVECTME
                     SNRRIRAEIKQIMINSSPQHSS"
     gene            complement(44862..45092)
                     /locus_tag="LSX49_000184"
     CDS             complement(44862..45092)
                     /locus_tag="LSX49_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166655.1"
                     /translation="MSDNGHFDFKKHWLALTPDEREAFAQEAGTTSHYIQTHLTGKRK
                     MPGKVLMNGLFKACKTRQWLRSKAELAYFFYS"
     gene            45247..45831
                     /locus_tag="LSX49_000185"
     CDS             45247..45831
                     /locus_tag="LSX49_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7166656.1"
                     /translation="MKSIQDVRRQNLNDLIDREFNGVQTRMAEKLGTQANLVNRWALG
                     KKVIGDQVARKIEAAANKPRNWLDIDRSLSQEGFQPVGPSDIGQLAAHNLERWMSESR
                     DLSTQGKLHRASGVAQVTISRLLNNEVSVSISTLENVASAFGRHGYELLIHPHDPATI
                     NYDRSRYALLPETEKAKIESYIEFVINQNEKNKQ"
     gene            45985..46137
                     /locus_tag="LSX49_000186"
     CDS             45985..46137
                     /locus_tag="LSX49_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166657.1"
                     /translation="MQWKIINGWYCVTACGFMSWKFRTLQEGIKWAFVSKEARDVAND
                     NEIWEG"
     gene            46140..46439
                     /locus_tag="LSX49_000187"
     CDS             46140..46439
                     /locus_tag="LSX49_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005028273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166658.1"
                     /translation="MNVNQQKNLQKIMLAFDKDYRLSEQLYDRQVELIESIRLHQLAS
                     TFDVVTVKGVRQEVLEAAKDSPEFEELMDAYRREAMAIIARWDLADQLDGQRDAA"
     gene            46436..47257
                     /locus_tag="LSX49_000188"
     CDS             46436..47257
                     /locus_tag="LSX49_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBL7166659.1"
                     /translation="MKPGIYFDISNEDYHAGDGVSKSQLDMVAKNPALLKWVQAAPED
                     EEKKSALDMGTALHCLLLEPGEFDKRFIVSPKFDRRTKQGKADEEEFLRDVADMGITV
                     LDAEQWRKLELMRDSAMAHPAARWMLEAPGYCEASMYWNDEETGELCRIRPDKWLNEH
                     NVIVDVKKVADMDRFARHIEEFRYHVQDAMYREGAMRVTGQPHGFFFLAVSESIDCGR
                     YPVRVFELDAQDVDAGHALFRRDLNTYHECRINDEWGGVEIIKRPEWARKQDMYI"
     gene            47254..48195
                     /locus_tag="LSX49_000189"
     CDS             47254..48195
                     /locus_tag="LSX49_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001509282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBL7166660.1"
                     /translation="MSNDIANINAPVDTAIAGTAATIFSPDGLNQLMKFAEVMAQSRV
                     TVPAHLAGKPADCMAVAMQAAQWGMNPFAVAQKTHVVNGTLGYEAQLVNAVISTMSPT
                     KDRINYEWFGPWERVIGKFVEKTSKNGNPYIAPGWTLKDEEGCGVRVWATMKGEDQPR
                     VLELMLSQAQVRNSTLWASDPKQQLAYLATKRWSRLHCPDVIMGVYTPDELQETAPRV
                     ERDITPQTTTAAGMNSLINAKPAKKPDEQTRKSDSRDPEEMLMAFTSAAMNYSTVSEL
                     DKAYKYIAQKLSDDDELLAKATDVYSVRREELNETSM"
     gene            48245..48493
                     /locus_tag="LSX49_000190"
     CDS             48245..48493
                     /locus_tag="LSX49_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009485476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HBL7166661.1"
                     /translation="MKGALGKKELLAVVPLSWSTIDRMERAGEFPKRWYITDKRCAWN
                     RDEVERWLDERQAASPAEFQGKKPPVQQRVYRPVSNAA"
     gene            48651..48902
                     /locus_tag="LSX49_000191"
     CDS             48651..48902
                     /locus_tag="LSX49_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001429704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HBL7166662.1"
                     /translation="MRSPSKIVAVTPAAIEIEKRAIEREKKGQFRIAAHLWLQCMDVA
                     SGDVERARIAVRRDQCITKGNGLRRGDYSGIGCCGVVYD"
     gene            48895..49545
                     /locus_tag="LSX49_000192"
     CDS             48895..49545
                     /locus_tag="LSX49_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine methylase"
                     /protein_id="HBL7166663.1"
                     /translation="MTKKYTLIYADPPWVYRDKAADGNRGAGFKYPVMSVLDICRLPV
                     WDLADENCLLAMWWVPTQPLEALKVVEAWGFRLMTMKGFTWIKCGSRQPDKLVMGMGH
                     MTRANSEDCLFAVKGKLPTRINAGIVQSFTAPRLEHSRKPDIVREKLVQLLGDVSRIE
                     LFARQTSHGFDVWGNQCEDPAVQLHPGYALDIGGLTNAFSNAPLSPTDNQGRERAA"
     gene            49542..50201
                     /locus_tag="LSX49_000193"
     CDS             49542..50201
                     /locus_tag="LSX49_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBL7166664.1"
                     /translation="MNLYQRINGADWCNIFVVGDLHGCYTLLMNELDKVSFDPARDLL
                     ISVGDLVDRGAENVECLDLITMPWFRAVRGNHEQMMLDALVNGGSFGHWMSNGGGWWH
                     QLDSEQDVQLKYLLPKVTNLPMIIELVTGNKKVVICHADYPHNEYAFDKPVPEEMVIW
                     NRERVSDAQDGIVSEITGADLFIFGHTPAHHPLVYANQMYIDTGAVFCGNLTLTKVQE
                     G"
     gene            complement(50204..51460)
                     /locus_tag="LSX49_000194"
     CDS             complement(50204..51460)
                     /locus_tag="LSX49_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL7166665.1"
                     /translation="MLTDTKLKNLKPQDKLYKVSDRDGLYVAVLTSGTVSFRYDYRIN
                     GRRETLVIGQYGRDGISLAEAREELIAAKKLLKAGQSPAAAKRDGIKKIRGAETFAVH
                     TDSYMKHVILADSTRAMKQAVIDRDILPVLGNKMMAEITTSMVRDLCDRIVERGGRAT
                     AVQAREIISSVYRHANDRGHGLFNPAADIKPSSIAIFKPRERTLTPEEIGLFFRTLDA
                     IGAMGTMKMALKLVLITMVRKGEFTNATWDEIDFKKWTWTIPSDRMKGSRAHVIYLPK
                     QAQDILVGLQMCAGGSEYLVPGRYNFRKPLSNAALNSLIDRTVKIINEDGEHIQDFTV
                     HDMRRTASTLLHEAGYPSDWIEKALAHEQKGVRAVYNKAEYARQRAYMLQQWADMIDS
                     WINGEHTDLIPFSPSKFEKWMEDSNK"
     gene            complement(51653..53230)
                     /gene="guaA"
                     /locus_tag="LSX49_000195"
     CDS             complement(51653..53230)
                     /gene="guaA"
                     /locus_tag="LSX49_000195"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL7166666.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(53299..54765)
                     /gene="guaB"
                     /locus_tag="LSX49_000196"
     CDS             complement(53299..54765)
                     /gene="guaB"
                     /locus_tag="LSX49_000196"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBL7166667.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLSQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            54927..56294
                     /gene="xseA"
                     /locus_tag="LSX49_000197"
     CDS             54927..56294
                     /gene="xseA"
                     /locus_tag="LSX49_000197"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBL7166668.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFHPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKAKLQAEGLFDLQYKKSLPSPAHCVGVITSKTGATLHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPIVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     ARQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRAGQQQQRLTRQLVHQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTSAADGAVLKQVKQVKVGDTLTTRLGDGVVVSEVSAVTKTRK
                     PRKKT"
     gene            complement(56348..64429)
                     /locus_tag="LSX49_000198"
     CDS             complement(56348..64429)
                     /locus_tag="LSX49_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RatA-like protein"
                     /protein_id="HBL7166669.1"
                     /translation="MSVCLKPGKIIVLLGMLAAFMLSDFARAEVEWQTYPGSTGEFNG
                     TVPIADSASVPVYQGSVQLDPAASHDVAFSAKPNEFSVDDDAANLIVANPQDSEGDQF
                     STPPALRWENQTPPTVSLVWADAATPDTPLNPQPIANRSFCAQGLAGRSLVAWPQIDA
                     QQTIPLLYLLTSTGYPYEGTVVLADQKVTLNIAPAQGDLISVSASGYNETLGAAKTTV
                     GGTITLTVTTKDCQGNVAGNIPFIIKRKDAQNRQGAVNNTAPVVLDSTELTTTVTEYR
                     GTSDANGTATITVTQPNGPGVKTPLVVGISGIAQTSEAAVIFTVLTSPDVAQATMWGH
                     MAETVEAHGYTFSRPKLAAEVSNENATVVDHNETWSTFTWSGADSHCTVLPGMRHFGA
                     LATVIPSTVQTVLGWPMQGDYYWSSLAGLTGQHHAADVSNRGETQKPDSTTFLVSCVD
                     KPAPDVEPKIVLTPENYDDTAQAMKAKVGEDATMRLAITDTKNNDQPLAYYYFSLHLD
                     DGVNRKNQTDTAWEAHPVQIAGGSNFRQVDAHTYEGMTDANGQASLTLSQPGGAGVKT
                     HITARMRSDFNATDAKDVIFTVITSPDSDKARMWGHMRGIIESGSLYKRPLLADETEH
                     ELGTVRENNEDWALYDQNTSMQAECGVGHIPRQSSLESLFSAHPGNAIGTEYGWPTAQ
                     QGYLSAVEQATHSSVDLGNGSVDSYSGFKPNYLSCSGNEMVANVEVSTDHDVSVGTQA
                     QAKVGDTIVMTVRTINSLNNIPVPFTAFTITKGMGYNRAGQVSGFDDPSSGAITMDNT
                     QYGTSQSSKVYAGITDARGVATVEIKQPQGVGLKTVLSVTPVNSYLPNTVNYSVIFTT
                     PTSPDVTGAQMWGHMDETITVDSSTFTRPKLASEVASPDGTLTENNEIWARVSQANTS
                     STSKGGCDTNMLPRRSQLSALYNANSGNAVQTAHGWPTQRQPYWSNSPADKTPHFFTI
                     ALNDGAQTIGGDTPVYVSCLKTANKPASSITLEVVDKAQWNTGNSAATLKKGETLQVK
                     VTVKDAQGNALADMPFTLNRGDGYTRSGEKHVAGSGDALVAPVVVNGGLADETTLNDT
                     ATVYTAMTDNDGSKILNITRPDTHGTKTALTAMLYSDATKKSSIDTIFTVVTSPDSRL
                     AKMWGHMPETVTAADGTVFKRPLLLKELAYQTGRTSTSEDNENWALFNINYASFSTTY
                     SGCGTNYIPTQAGLTSLFANNAGNTMKTVQGWPVATRYLSNTSDNGSMEQRNYKAVDL
                     SNGTSAAVSSTTLELLTCQTAPIAAVSQILLEAADPVTLDTTYNVVKAKKSEESVVRV
                     ITKDAQGNLVGNTAFILTRANSVSRANSSATMSVGALTVTDAWGNTRNNFQSTSETIY
                     GVTGADGSTTFTLKQDNSTGLRTDLTAKLDTSSSVKAMLPVVFTVVTSPDSPKANFWG
                     HMAETVTASDGSVYKRPLLFGELTNNYARYSTFENGESWARFTSTQSADTSMNGCGTD
                     YMPTLDGLKSLYDANRGNAMNTVQGWPVNMSYLTNTPSNTQTGSRYYNVVQLNSGAVS
                     QIVSTVLALQTCRTTPLMTASQITLEASDPGQFVSIDSTLSAVKAKKGDEVSIRISTK
                     DAQGNLVGNTPFALKHANSINRQNVTSSQKVSVTTAAGATVDTSATTILYGVTGPDGT
                     TTMTLRQDASTGLRTDFYALLNDTGVSSDTLSVIFTVTTSPDTPLATNWGHMAETFTS
                     SEGVTFKRPFLKAELSGGTAKTANNEVWSLLTATEKADVSKAGCDEAYQPLTTDMQGL
                     YVDYPNGQLATVLGLPTAAGNWWDYDMMAVAGGSWSNQAFVPGNGQLIQASSSYTAIV
                     MCLVEPHTEAVTIELTSTAQDAAKSLSNDGRPSAVAKKGELIPLTVTVRDSAGNPMPY
                     ADFTLSRETTLDRAKATVNTSADDLTVTALVPVSRDSVLTASGAKTLATTGSDGTATF
                     EVGQYSTTGLATPLTVTLARDTTKVATLDVIYTVITSPDSPSAKFWGHMPDTFTSSAG
                     VTFKRPLLKTETSSGLSISSNGEVWSYMSNLQNLTSTDCPLENQPRSKELLDLYSDHP
                     NGAIMTDLGLPMNAGNWWAYDMAILGTTTWSYQTVSLRTGAIAKNSATNALMLCLAQP
                     HPAGVSVTLTSSALDDARTLSNGGRPSASVKKDNPLPIVVMVKDRDGNPLAGEAITLR
                     RDNAMSRSGTIVNTAANVMVLTELAPVSATFTLASHGTQWLGFTGSDGTAIFNVEQPD
                     TVGLATPFTAILARDTETTTVLDAIFTVVTSPDSAMAAYWGHMPDTVTAENGVVFERP
                     KLWKELPSTSGVSKVNSNNEVWPVFNATQRADSNLSPCEAARRPLSDDLESLYARYPG
                     NTLTTQIGWSTQYTWWALDNWLGGSNPQVVGLNNGSAWGTVNTAYQGCLVNPRATVSS
                     VTLTSTALDSSTQAAKVKKGDAVPVVVTVKDSVGKPVPNISFILKRGDATPRNSGATL
                     YGDVDTMDDLTVQPSSGAAVTLADSGNTIDGVTGADGTASFTVGQDNTPGYKTPLTVT
                     LTDNATITATLDTIFTVPTSPNVATAYFWGHMADTATVSGKMLHRPLLKSELPSGVTA
                     AATPNVNNETWALAHVIDSTKWDVARQCGSMNNVPSSAELQTLHSGFSTLGWPSSISF
                     PYLSTDKAGSFYCGVEEGSGSLNCGIQPAKTPGFATCFQ"
     gene            complement(64539..65531)
                     /locus_tag="LSX49_000199"
     CDS             complement(64539..65531)
                     /locus_tag="LSX49_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166670.1"
                     /translation="MKPHMKRGLTKVALALMLAGYCAVPVAMAEDAAWVASGTTAEFE
                     GTIPWLYREGGNATINSEDADHIKVTSDSKGIRPAGSESDKRLYSGDTITLGWDIGDT
                     EGDIDDGSAGIDAKTTATIKWYSYSDNAGGGKTELTAAAGKTSYKITDGDRGRYIGVE
                     IQPITQTGNPFQGTSLTLLDISTASGGGSDTDNVDPGPVVNQNLKVAIFEKDTSTNLI
                     GGNTAIALNKTYVAKLYSDENQNGKYDAGTDVDVTANYDFAWVFNGNSKQLAAAGGIA
                     NASFDNNDIVIPQTNEQARTSLNGSDRNGKTGLAIPANGDGVQGYTLSIIYKHH"
     gene            complement(65587..67761)
                     /gene="sinH"
                     /locus_tag="LSX49_000200"
     CDS             complement(65587..67761)
                     /gene="sinH"
                     /locus_tag="LSX49_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001385430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like inverse autotransporter SinH"
                     /protein_id="HBL7166671.1"
                     /translation="MLRWKRCIMLTFISGAAFAAPEINVKQNESLPDLGSQAAQQDEQ
                     TNKGKSLKERGADYVINSATQGFENLTPEALESQARSYLQSQITSTAQSYIEDTLSPY
                     GKVRSNLSIGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHN
                     FDKWLLGGNIFYDYDFTRGHRRLGIGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEE
                     RPASGWDIRAEAWLPAYPQLGGKIVFEHYYGDEVALFGTDNLEKDPFAVTLGVKYQPV
                     PLIAVGTDFKAGTGDNTDTTVNATLNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVER
                     NNFIVLEYKEKDPLDVTLWLKADAMNEHPECVIKDTPEEAIGLEKCKWTINALVNHHY
                     KIVAASWQAKNNAARTLVMPVIKENTLTEGNNNHWNLVLPVWQYSSDKAEQGKLNTWR
                     VRLALKDEKGNRQNSGVVEITVQQDRKIELIVNNIANVPEENNHSHEASAQADGVDGV
                     VMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTNNPCTTETPCVFIAKQD
                     KEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGADIGGLNAFIYRVGAAKSVNL
                     IGNKEPLPLNSRYRFVLWRDANKDGVFQLSEKLTDEEMKQYDYQWEFTGHSVNGNTGA
                     QANTTNVDIEIPATNKEAAAKFSAQVTDGVQGYGLQVNYSKT"
     gene            complement(67967..68182)
                     /locus_tag="LSX49_000201"
     CDS             complement(67967..68182)
                     /locus_tag="LSX49_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBL7166672.1"
                     /translation="MALNCPTCKTPLERNGETAHCATCDKDFTVQALCPECHQPLQVL
                     KACGAVDYFCQHGHGLISKKRVEFVIA"
     gene            complement(68245..69717)
                     /gene="der"
                     /locus_tag="LSX49_000202"
     CDS             complement(68245..69717)
                     /gene="der"
                     /locus_tag="LSX49_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBL7166673.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYALGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     SPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK"
     gene            complement(69835..71013)
                     /gene="bamB"
                     /locus_tag="LSX49_000203"
     CDS             complement(69835..71013)
                     /gene="bamB"
                     /locus_tag="LSX49_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HBL7166674.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTVWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVNLAEKDG
                     WFSKDPALLSGGVTVSGGHVYIGTEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            complement(71024..71644)
                     /gene="yfgM"
                     /locus_tag="LSX49_000204"
     CDS             complement(71024..71644)
                     /gene="yfgM"
                     /locus_tag="LSX49_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ancillary SecYEG translocon subunit YfgM"
                     /protein_id="HBL7166675.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDAIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            complement(71662..72936)
                     /gene="hisS"
                     /locus_tag="LSX49_000205"
     CDS             complement(71662..72936)
                     /gene="hisS"
                     /locus_tag="LSX49_000205"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBL7166676.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQVL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            complement(73047..74165)
                     /gene="ispG"
                     /locus_tag="LSX49_000206"
                     /gene_synonym="gcpE"
     CDS             complement(73047..74165)
                     /gene="ispG"
                     /locus_tag="LSX49_000206"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBL7166677.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            complement(74192..75199)
                     /gene="rodZ"
                     /locus_tag="LSX49_000207"
     CDS             complement(74192..75199)
                     /gene="rodZ"
                     /locus_tag="LSX49_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HBL7166678.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELNNNQSQ
                     SVPLDTSTTTDQAMATTPTSPVDTTATNTQTPAVTAPAPAVDPQQNAVVPPSQANVDT
                     AATPAPAATTTPDGAAPLPTDQAGVTTPAVDPNALVMNFTSDCWLEVTDATGKKLFSG
                     MQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPA
                     Q"
     gene            complement(75484..76638)
                     /gene="trmG/rlmN"
                     /locus_tag="LSX49_000208"
     CDS             complement(75484..76638)
                     /gene="trmG/rlmN"
                     /locus_tag="LSX49_000208"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HBL7166679.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            complement(76788..77219)
                     /gene="ndk"
                     /locus_tag="LSX49_000209"
     CDS             complement(76788..77219)
                     /gene="ndk"
                     /locus_tag="LSX49_000209"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBL7166680.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            complement(77368..79680)
                     /gene="pbpC"
                     /locus_tag="LSX49_000210"
     CDS             complement(77368..79680)
                     /gene="pbpC"
                     /locus_tag="LSX49_000210"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HBL7166681.1"
                     /translation="MPRLLTKRGCWIMLTAAPFIIILAAWAADKLWPLPLQEVNPARV
                     VVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAA
                     RNKVLERMAVQGVWSRERVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMV
                     NAIRSPGSVLKPFAYGLALDEGVIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAQPLPDGALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSVNLPEDPRPDSVSRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPEQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTICP
                     PYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDDVGQIATVKFVMQ"
     gene            complement(79681..84642)
                     /gene="yfhM"
                     /locus_tag="LSX49_000211"
     CDS             complement(79681..84642)
                     /gene="yfhM"
                     /locus_tag="LSX49_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HBL7166682.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     VSSAKLSAPERQKLAQQSAGKALTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDDEKTIT
                     TRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAALQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKNGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPDQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSV
                     VGYYLYGALANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASK
                     SVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     YEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGGGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVPAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPTKMRPNQPLTVKIKASNKNGEMPKQVNVLVSAVDSGVLNITDYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVAQQA
                     LPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSNSPAPVELAPGVRTTLFIPVR
                     ALTGYGDGDIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAL
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDAINRGNERLLRYLQDPGMISIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKIMGDATRGEEAIVLALKTPRNSDERIW
                     LGDYGSPLRDSALMLSLLEENKLLPDEQYSLLNTLSQQAFGERWLSTQESNALFLAAR
                     TLQDLPGKWQAQTTFSAEPLTGEKAQTSNLNSDQLATLQVTNSGDQPLWLRVDASGYP
                     QSAPLPASNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLP
                     AGLELENQNLANGGASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPV
                     TLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAADDLLIVRP"
     gene            84849..85694
                     /gene="sseA"
                     /locus_tag="LSX49_000212"
     CDS             84849..85694
                     /gene="sseA"
                     /locus_tag="LSX49_000212"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HBL7166683.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWLRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDV
                     LLASHENTAQIIDARPATRFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPVK"
     gene            complement(86187..86963)
                     /gene="sseB"
                     /locus_tag="LSX49_000213"
     CDS             complement(86187..86963)
                     /gene="sseB"
                     /locus_tag="LSX49_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HBL7166684.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGEEGNPLSSQEVLEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKPVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQVAGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIAPFYERRWGGFLRDFKQNRII"
     gene            complement(87105..88388)
                     /gene="pepB"
                     /locus_tag="LSX49_000214"
     CDS             complement(87105..88388)
                     /gene="pepB"
                     /locus_tag="LSX49_000214"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HBL7166685.1"
                     /translation="MTEAMKITLSTQPADVRWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKVDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPELDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLICNVAGDRVTYRITKGEDLREQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     ASQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA"
     gene            complement(88447..88647)
                     /gene="iscX"
                     /locus_tag="LSX49_000215"
     CDS             complement(88447..88647)
                     /gene="iscX"
                     /locus_tag="LSX49_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HBL7166686.1"
                     /translation="MGLKWTDSREIGEALYDAYPDIDPKTVRFTDMHQWICALEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            complement(88659..88994)
                     /gene="fdx"
                     /locus_tag="LSX49_000216"
     CDS             complement(88659..88994)
                     /gene="fdx"
                     /locus_tag="LSX49_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HBL7166687.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDVALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            complement(88996..90846)
                     /gene="hscA"
                     /locus_tag="LSX49_000217"
     CDS             complement(88996..90846)
                     /gene="hscA"
                     /locus_tag="LSX49_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HBL7166688.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            complement(90863..91378)
                     /gene="hscB"
                     /locus_tag="LSX49_000218"
     CDS             complement(90863..91378)
                     /gene="hscB"
                     /locus_tag="LSX49_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HBL7166689.1"
                     /translation="MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            complement(91474..91797)
                     /gene="iscA"
                     /locus_tag="LSX49_000219"
     CDS             complement(91474..91797)
                     /gene="iscA"
                     /locus_tag="LSX49_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HBL7166690.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            complement(91814..92200)
                     /gene="iscU"
                     /locus_tag="LSX49_000220"
     CDS             complement(91814..92200)
                     /gene="iscU"
                     /locus_tag="LSX49_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HBL7166691.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            complement(92228..93442)
                     /gene="iscS"
                     /locus_tag="LSX49_000221"
     CDS             complement(92228..93442)
                     /gene="iscS"
                     /locus_tag="LSX49_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL7166692.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            complement(93554..94042)
                     /gene="iscR"
                     /locus_tag="LSX49_000222"
     CDS             complement(93554..94042)
                     /gene="iscR"
                     /locus_tag="LSX49_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HBL7166693.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKL
                     RA"
     gene            complement(94313..95053)
                     /gene="trmJ"
                     /locus_tag="LSX49_000223"
     CDS             complement(94313..95053)
                     /gene="trmJ"
                     /locus_tag="LSX49_000223"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HBL7166694.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKAE"
     gene            95172..95975
                     /gene="suhB"
                     /locus_tag="LSX49_000224"
     CDS             95172..95975
                     /gene="suhB"
                     /locus_tag="LSX49_000224"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HBL7166695.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            96120..96974
                     /locus_tag="LSX49_000225"
     CDS             96120..96974
                     /locus_tag="LSX49_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417029.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7166696.1"
                     /translation="MALPVNKRVLKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSLAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILDVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            97165..98445
                     /gene="csiE"
                     /locus_tag="LSX49_000226"
     CDS             97165..98445
                     /gene="csiE"
                     /locus_tag="LSX49_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HBL7166697.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATTATFSELNGVDD
                     DIASLDISETGREILRYHQLTLTTGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSRFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFETRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKAFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(98437..99576)
                     /locus_tag="LSX49_000227"
     CDS             complement(98437..99576)
                     /locus_tag="LSX49_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HBL7166698.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVSMFDYRVIL
                     ALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAIC
                     GVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            99946..100368
                     /locus_tag="LSX49_000228"
     CDS             99946..100368
                     /locus_tag="LSX49_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311436.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HBL7166699.1"
                     /translation="MNSLRYFDFGTARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQ
                     YMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAVIGHHYWDM
                     TGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR"
     gene            complement(100416..101288)
                     /locus_tag="LSX49_000229"
     CDS             complement(100416..101288)
                     /locus_tag="LSX49_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HBL7166700.1"
                     /translation="MTIYTLSHGPLKLDVSDQGGVIEGFWRDTTPLLRPGKKSGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSRSDDSLC
                     LVYEHLSGVYHYRVSQAFHLTADTLTVTLAVTNQGAETLPFGTGWHPYFPLSPQTRIQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFNQLAPLPRQWVNNGFAGWNGKARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTISEMSLRVALL"
     gene            complement(101300..102394)
                     /locus_tag="LSX49_000230"
     CDS             complement(101300..102394)
                     /locus_tag="LSX49_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBL7166701.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGEGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            complement(102427..103425)
                     /locus_tag="LSX49_000231"
     CDS             complement(102427..103425)
                     /locus_tag="LSX49_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7166702.1"
                     /translation="MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEV
                     PLAIACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPIN
                     ENEVLDWLGGQFLGVPVSALIMMVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRG
                     SLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            complement(103428..104957)
                     /locus_tag="LSX49_000232"
     CDS             complement(103428..104957)
                     /locus_tag="LSX49_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL7166703.1"
                     /translation="MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLKKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIMDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLETYEQGEIVINGEKIMRPDYGDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHSPVNVDELMSAILSTDEFYRG
                     T"
     gene            complement(104980..105963)
                     /locus_tag="LSX49_000233"
     CDS             complement(104980..105963)
                     /locus_tag="LSX49_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL7166704.1"
                     /translation="MPKKMTRTRNLLLMATLLGSALFARASDKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
                     QPKIAVINCEAFEVCVQRRKGFEEVLKTRVPGAQIVANQEGTVLDKAISVGEKLIIST
                     PDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVFTQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            complement(106060..109341)
                     /locus_tag="LSX49_000234"
     CDS             complement(106060..109341)
                     /locus_tag="LSX49_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HBL7166705.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHDDGAQTVWVGETESMHGLQVMT
                     GFTLRPDRAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCN
                     ALLDDAVALTPATAIQGVLHGINPERLTIELSDADGNIVLSYHEHQPQALPLPDVAKA
                     PLAAQDITSTDEAWFIGQHLEQYHHASRSPFDYYLRGVALDPLDYRCNLALAMLEYNR
                     ADFPQAVVYASQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGNFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARL
                     QREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPAL
                     AADMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDAFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYGKAIALWQRCVEMSPEFADGWRGLAIHAWNKQHDYELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGVTPEKRLARLEDNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQHLDDREPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAVCANAQGDETEATRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQQTAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLAAAGLGEVAHYESARAELMAINPAWPKAALFTTVMPFI
                     FSYVH"
     gene            109459..110652
                     /locus_tag="LSX49_000235"
     CDS             109459..110652
                     /locus_tag="LSX49_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL7166706.1"
                     /translation="MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
                     MPQAPWATPIEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQVRDFCVINVDYGIG
                     SSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLNPEKLTTAQLIAAWQSGEPWFTSWVDHSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            complement(110716..111969)
                     /gene="glyA"
                     /locus_tag="LSX49_000236"
     CDS             complement(110716..111969)
                     /gene="glyA"
                     /locus_tag="LSX49_000236"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBL7166707.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            112298..113488
                     /gene="hmpA"
                     /locus_tag="LSX49_000237"
     CDS             112298..113488
                     /gene="hmpA"
                     /locus_tag="LSX49_000237"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HBL7166708.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAVAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            complement(113533..113871)
                     /gene="glnB"
                     /locus_tag="LSX49_000238"
     CDS             complement(113533..113871)
                     /gene="glnB"
                     /locus_tag="LSX49_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HBL7166709.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(113932..115266)
                     /gene="glrR"
                     /locus_tag="LSX49_000239"
     CDS             complement(113932..115266)
                     /gene="glrR"
                     /locus_tag="LSX49_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HBL7166710.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRNELDANDFKE"
     gene            complement(115256..115969)
                     /gene="qseG"
                     /locus_tag="LSX49_000240"
     CDS             complement(115256..115969)
                     /gene="qseG"
                     /locus_tag="LSX49_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HBL7166711.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQSHNRPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGNWQ
                     NTFKQGILLADAKITPYERRQLVARIDALSTEIPAQVRPLYQLWRDGQALQLQLAEER
                     QRYSKLQQSSDSELDTLRQQHHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHESEKPAPSTDEVTPDEP"
     gene            complement(116134..117561)
                     /gene="qseE"
                     /locus_tag="LSX49_000241"
     CDS             complement(116134..117561)
                     /gene="qseE"
                     /locus_tag="LSX49_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HBL7166712.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETL
                     VSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSL
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
     gene            complement(118137..122024)
                     /gene="purL"
                     /locus_tag="LSX49_000242"
                     /gene_synonym="purI"
     CDS             complement(118137..122024)
                     /gene="purL"
                     /locus_tag="LSX49_000242"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBL7166713.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGMAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
                     VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWIIDGEQQPKSLFKMIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKDEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDADIASLGD
                     DRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVSGDRFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APFIATGVRPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTGLEGFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            122282..123838
                     /gene="mltF"
                     /locus_tag="LSX49_000243"
     CDS             122282..123838
                     /gene="mltF"
                     /locus_tag="LSX49_000243"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HBL7166714.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKDTKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            complement(123835..124371)
                     /gene="tadA"
                     /locus_tag="LSX49_000244"
     CDS             complement(123835..124371)
                     /gene="tadA"
                     /locus_tag="LSX49_000244"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBL7166715.1"
                     /translation="MRRAFITGVFFLSEVEFSYEYWMRHAMTLAKRAWDEREVPVGAV
                     LVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCA
                     GAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFF
                     RMRRQEIKAQKKAQSSTD"
     gene            complement(124396..125031)
                     /gene="yfhb"
                     /locus_tag="LSX49_000245"
     CDS             complement(124396..125031)
                     /gene="yfhb"
                     /locus_tag="LSX49_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311453.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HBL7166716.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHNEARLQALQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE"
     gene            125240..126088
                     /locus_tag="LSX49_000246"
     CDS             125240..126088
                     /locus_tag="LSX49_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL7166717.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRHSEA
                     LVKKLV"
     gene            126144..126404
                     /gene="yfhL"
                     /locus_tag="LSX49_000247"
     CDS             126144..126404
                     /gene="yfhL"
                     /locus_tag="LSX49_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster ferredoxin YfhL"
                     /protein_id="HBL7166718.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGEHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPQHVETEEQLWDKFVLMHHADKI"
BASE COUNT        30610 a        33981 c        30610 g        31264 t
ORIGIN      
        1 aggcccggaa taatgtatcc gtgctcgttc agtccctggt caatcgatgc agtatacagt
       61 tcgacgtccg ggtgcgcttt ttccagcgca gcgatacctt ctggtgcagc taccagcacc
      121 agaactttga tgctgctgca gcccgctttt ttcagcaggt cgatggtcgc gataacggaa
      181 ccaccggttg ccagcattgg gtcaacgatc agcgccatac gctcatcgat gttagaaacc
      241 agtttctgga agtacggtac cggctccagc gtttcttcat tacggtacat accgacgacg
      301 ctgatgcgcg cgctcggaac gttttccagc acaccgtcca tcatccccag acccgcacgc
      361 agaattggca caacggtaat tttcttacct ttgatctggt cgatttctac cgggccgttc
      421 cagccttcga tagttacttt ttccgtttcg aggtcggcgg tcgcttcgta agtcagcagg
      481 ctacccactt cggaagcgag ttcgcgaaag cgcttggtgc tgatatcttg ctcacgcatc
      541 agtcccagct tgtgtttgac gagtgggtgt ttgacttcca cgatcttcat actctttctc
      601 ctttgagggg cagccacaaa aaaaatcgac ggattatacc tcctttcttc aaggcggcaa
      661 tattattttc gttgacttta gtcaaaatga taacggtttg agataaagtt attttatatt
      721 caaatagtta tgaaagaaga ttattccatc cgaaaacgat cctttgccct ggtacaagta
      781 ttctttcgcc gcgcgcctgg ggaaaagacg tgcaaaaagg ttgtgtaaag cagtctcgca
      841 aacgtttgct ttccctgtta gaattgcgcc gaattttatt tttctaccgc aagtaacgcg
      901 tggggaccca agcagtgacc gataaaacct ctcttagcta caaagatgcc ggtgttgata
      961 ttgacgcggg taatgctctg gttggaagaa tcaaaggcgt agtgaagaaa acgcgtcgtc
     1021 cggaagtgat gggcggtctg ggcggcttcg gtgcgctgtg tgcattgccg caaaaatatc
     1081 gtgaacctgt gctggtttcc ggcactgacg gcgtaggtac caagctgcgt ctggcgatgg
     1141 acttaaaacg tcacgacacc attggtattg atctggtcgc catgtgcgtt aatgacctgg
     1201 tggtgcaagg tgcggaaccg ctgtttttcc tcgactatta cgcaaccgga aaactggatg
     1261 ttgataccgc ttcagcggtg atcagcggca ttgcggaagg ttgtctgcaa tcgggctgtt
     1321 cactggtggg tggcgaaacg gcggaaatgc cggggatgta tcacggtgaa gattacgatg
     1381 tcgctggttt ctgcgttggc gtggtagaaa aatcagaaat catcgacgga tctaaagtca
     1441 gcgacggcga tgtgctgatt gcactcggct ccagcggccc gcactcgaac ggctattcgc
     1501 tggtgcgcaa aattcttgaa gtcagcggtt gtgatccgca aaccaccgaa cttgatggta
     1561 agccattagc cgatcatctg ctggcaccga cccgcattta cgtgaagtca gtgctgaaat
     1621 tgattgaaaa ggtcgatgtg catgccattg cgcacctgac cggcggcggc ttctgggaaa
     1681 acattccgcg cgtattgcca gataataccc aggcagtgat tgatgaatct tcctggcagt
     1741 ggccggaagt gttcaactgg ctgcaaacgg caggtaacgt tgagcgccat gaaatgtatc
     1801 gcaccttcaa ctgcggcgtc ggtatgatta ttgccctgcc tgctccggaa gtggacaaag
     1861 ccctcgccct gctcaatgcc aacggtgaaa acgcgtggaa aatcggtatc atcaaagcct
     1921 ctgattccga acaacgcgtg gttatcgaat aatgaatatt gtggtgctta tttccggcaa
     1981 cggaagtaat ttgcaggcaa ttattgacgc ctgcaaaacc aacaaaatta aaggcaccgt
     2041 acgggcagtt ttcagcaata aggccgacgc gttcggcctt gaacgcgccc gccaggcggg
     2101 tattgcaacg catacgctca tcaccagcgc gtttgacagt cgtgaagcct atgaccggga
     2161 gttgattcat gaaatcgaca tgtacgcacc cgatgtggtc gtgctggctg gttttatgcg
     2221 cattctcagc ccggcgtttg tctcccacta tgctgggcgt ttgctgaaca ttcacccttc
     2281 tctgctgccg aaatatcccg gattacacac ccatcgtcag gcgctggaaa atggcgatga
     2341 agagcacggt acatcggtgc atttcgtcac cgatgaactg gacggtggcc cggttatttt
     2401 acaggcgaaa gtcccggtat ttgctggtga tacggaagat gacatcaccg cccgcgtgca
     2461 aacccaggaa cacgctattt atccactggt gattagctgg tttgccgatg gtcgtctgaa
     2521 aatgcacgaa aacgccgcgt ggctggatgg tcaacgtctg ccgccgcagg gctacgctgc
     2581 cgacgagtaa tgcccccgta gttaaagcgc cagctctgcc gctggcgttt ttcaattcac
     2641 ctgtaaatcg caagctccag cagttttttt cccccttttc tggcatagtt ggacatctgc
     2701 caatattgct cgccataata tccaggcagt gtcccgtgaa taaaacggag taaaagtggt
     2761 aatgggtcag gaaaagctat acatcgaaaa agagctcagt tggttatcgt tcaatgaacg
     2821 cgtgcttcag gaagcggcgg acaaatctaa cccgctgatt gaaaggatgc gtttcctggg
     2881 gatctattcc aataaccttg atgagttcta taaagtccgc ttcgctgaac tgaagcgacg
     2941 catcattatt agcgaagaac aaggttccaa ctctcattcc cgccatttac tgggcaaaat
     3001 tcagtcccgg gtgctgaaag ccgatcagga attcgacggc ctctacaacg agttgttgct
     3061 agagatggcg cgcaaccaga tcttcctgat taatgaacgc cagctctccg tcaatcaaca
     3121 aaactggctg cgtcattatt ttaagcagta tctgcgtcag cacattacgc cgattttaat
     3181 caatcctgac actgatttag tgcagttcct gaaagatgat tacacctatc tggcggtgga
     3241 aattatccgt ggcgatacca tccgttacgc gctgctggag atcccatcag ataaagtgcc
     3301 gcgctttgtg aatttaccgc cagaagcgcc gcgtcgacgc aagccgatga ttcttctgga
     3361 taacattctg cgttactgcc ttgatgatat tttcaaaggc ttctttgatt atgacgcgct
     3421 gaatgcctat tcaatgaaga tgacccgcga tgccgaatac gatttagtgc atgagatgga
     3481 agccagcctg atggagttga tgtcttccag tctcaagcag cgtttaactg ctgagccggt
     3541 gcgttttgtt tatcagcgcg atatgcccaa tgcgctggtt gaagtgttac gcgaaaaact
     3601 gactatttcc cgctacgact ccatcgtccc cggcggtcgt tatcataatt ttaaagactt
     3661 tattaatttc cccaatgtcg gcaaagccaa tctggtgaac aaaccactgc cacgtttacg
     3721 ccacatttgg tttgataaag cccagttccg caacggtttt gatgccattc gtgagcgcga
     3781 tgtgctgctc tattatcctt atcatacctt tgagcatgta ctggaactgc tgcgtcaggc
     3841 ttcgttcgac ccgagcgtac tggcgattaa aattaacatt taccgcgtgg cgaaagattc
     3901 acgcatcatc gactcgatga tccacgccgc acacaacggt aagaaagtca ccgtggtggt
     3961 tgagttacag gcacgtttcg acgaagaagc caacattcac tgggcgaagc gcctgaccga
     4021 agcaggcgtg cacgttatct tctctgcgcc ggggctgaaa attcacgcca aactgttcct
     4081 gatttcacgt aaagaaaacg gtgaagtggt gcgttacgca cacatcggga ccgggaactt
     4141 taacgaaaaa accgcgcgtc tttatactga ctattcgttg ctgaccgccg atgcgcgcat
     4201 cactaacgaa gtacggcggg tgttcaactt tattgaaaac ccataccgtc cggtgacatt
     4261 tgattattta atggtgtcgc cgcaaaactc tcgccgtctg ttgtatgaaa tggtggaccg
     4321 cgagatcgcc aacgcgcagc aagggctgcc cagtggtatc accctgaagc taaataacct
     4381 tgtcgataaa ggtctggttg atcgtctgta tgcggcctcc agctccggcg taccggttaa
     4441 tctgctggtg cgcggaatgt gttctctgat ccccaatctg gaaggcatta gcgacaacat
     4501 tcgtgccatc agtattgttg accgttacct tgaacatgac cgggtttata tttttgaaaa
     4561 tggcggcgat aaaaaggtct acctttcttc cgccgactgg atgacgcgca atattgatta
     4621 tcgtattgaa gtggcaacgc cgctgctcga tccgcgcctg aagcagcggg tgctggacat
     4681 catcgacata ttgttcagcg atacggtcaa agcacgttat atcgataaag aactcagtaa
     4741 tcgctacgtt ccccgcggca atcgccgcaa agtacgggcg cagttggcga tttacgacta
     4801 catcaaatca ctcgaacaat ctgaataacc ctatgccaat acacgataaa tcccctcgtc
     4861 cgcaggagtt tgctgcggtc gatcttggtt caaacagttt tcacatggtc atagcccgtg
     4921 tggtagatgg tgccatgcag attattggcc gcctgaaaca gcgggtgcat ctggcggacg
     4981 gcctggggcc agataatatg ttgagtgaag aggcaatgac gcgcggtttg aactgtctgt
     5041 cgctatttgc cgaaaggcta caagggtttt cccctgccag cgtctgtata gttggtaccc
     5101 atacgctgcg tcaggcgctg aacgccactg actttctgaa acgcgcggaa aaagtcattc
     5161 cctacccgat cgaaattatt tccggtaatg aagaagcccg tctgattttt atgggcgtgg
     5221 aacataccca accggaaaaa ggtcgcaaac tggttattga tattggcggc ggttctacag
     5281 aactggtgat tggtgaaaat ttcgaaccga ttctcgttga aagccgccgg atgggttgtg
     5341 tcagctttgc ccagctttat ttccctggcg gggtcatcaa taaagagaat tttcagcgcg
     5401 ctcgcatggc ggcagcacaa aaactggaaa cgttaacctg gcaatttcga attcagggct
     5461 ggaacgtggc aatgggcgct tccggtacca taaaagccgc ccatgaagtg ttaatggaaa
     5521 tgggcgagaa agacgggata attaccccgg aacgtctgga aaaactggta aaagaagttt
     5581 tacgtcaccg taatttcgca tcgctgagtt taccgggtct ttccgaagaa cggaaaacag
     5641 tcttcgttcc gggactggcg attttatgcg gtgtgtttga tgctttagcc atccgtgaac
     5701 tgcgcctttc tgacggggcg ttacgcgaag gcgtactgta tgaaatggaa ggacgtttcc
     5761 gtcatcagga tgtgcgtagt cgcactgcca gcagcctcgc caaccagtat cacatcgaca
     5821 gcgaacaggc ccgacgggtg ctggatacca ctatgcaaat gtacgaacag tggcgggaac
     5881 agcaaccgaa gctggcgcat ccacaactgg aggcgctact gcgatgggcc gccatgctgc
     5941 atgaggtcgg gttgaatatc aaccacagcg gtttgcatcg ccactccgct tatattctgc
     6001 aaaacagcga cttgccgggt tttaatcagg aacagcagct gatgatggcg acactggtgc
     6061 gctatcaccg taaagcgatt aaactcgacg atctgccgcg ctttaccttg tttaagaaga
     6121 aacagttcct gccactgatt cagctattgc gccttggcgt attactcaat aatcaacgtc
     6181 aggcaaccac cacaccgcca acattgacgc tgattactga tgacagtcac tggacactgc
     6241 gtttcccgca tgactggttt agtcagaatg cgctggtact gcttgatctg gaaaaggagc
     6301 aagaatactg ggaaggcgtg gctggctggc ggttgaaaat tgaagaagaa agtacaccag
     6361 aaatcgccgc ttaatgcttt gcgggccgac gagaaatgtc ggcccgcatt attcaggcac
     6421 tttcgcgaat gggttcgatt tcattcagcg tatcaattaa cggttgcggc ttaccaataa
     6481 gataaccctg catataatcg atccccaaag agagcaccgc ctcgcggatc tcttcgtttt
     6541 caacgtactc tgccactacc cgcattttct tcattcgcgc caggtggcaa atcgacgcca
     6601 ctatctgata atccagacta tttgacacaa tattgcggat aaaactgccg tcaattttaa
     6661 gcagatcggc attcacattt ttaagccgcg catagctggc gtagccggtg ccgaaatcat
     6721 caatcgcaat ctggcagcct aattcctgaa gatgctgcaa ggtgatttgc gcctgcttaa
     6781 cattggtcag agcattactt tcggtgactt caaaaataag ttgccacgct tcaatctgat
     6841 atttagccag cagctgactg acttcaacag gaaaacgagc ctgacatacc gaggttggag
     6901 acagattaat agcaaaacgg tgagcgggca tcttcgctct gttttcagcc ataaattgca
     6961 gcgtatgctc aatgacccac atgtcgatac tcgacgataa accaaattcg tgcgcgaccg
     7021 gtaagaagct atcggggctg atcagctcat cattctcacc cttcatgcgc agaagaattt
     7081 catggtaaac atcaccacgc ataccggtaa tcggctgggc catcaggaaa aaatggttgt
     7141 gttccagcgc ctgctgtagt cgattcatca tcgcgacttt atctttcaat tcgcgttgca
     7201 aatacattgc tccgcgacgc tgcatatttt ccgggacgtt ggtcacgatg gaaagttcgg
     7261 ccaccgtatt tagctctccc agcagcaggt agatatgatt cactggcgag cgcacatagc
     7321 agtaactgac gccaatctgc ggttgcatcg gcattccatc ccaaaagaaa cgaaattgct
     7381 tgagatggct atccagtgcg gtaatgcgct cctggtgcga ttctgtattc agccgcagcg
     7441 cgagatcgtt acccgaaagc tgataaacat cttcacccgg ttccagcaat ggtgacagcc
     7501 agtgagaaag tttttgcttg tattgaatcc gcagcatgat gccatagttc ttaaccagca
     7561 tttccatgcc agggatgtgt aaatagcata gcgcagacca gggggcatca cgcaacgcgc
     7621 gattcagggc gcgaacattt ggcagatgaa ccaccgggtc cacatacgca agccgctgaa
     7681 tgcgtctgac tacagctcgc tgacgggttg ccagtacagc catataattg acaataaaag
     7741 agaataccag ataactggag gaggttatgg tcagctgcgt ggtatagcca ggataaatgg
     7801 gaatgtaatt ttgatagcta tggatgctga tcatcaacac gaccgcccag agcaatgaaa
     7861 tcaacttata accatagcgc atcgctcccc acatcatcag gggcagcaat aatgacaagg
     7921 tgtaattggt gctaaaaatc gtgctttttt catttaacgg catgcataac agcaacaata
     7981 aggcacctaa tgccagtagc cagattgcga actctttttt ggtaactttg gcatcaacct
     8041 gctgttttaa ttgcgaataa tagctacgta aataaaacgg atttcgcacc acccgaatga
     8101 taaagtagca cagcgggaca ccaatcagat tacccaccag caaggcctga taattgatta
     8161 aggtcccgag gttaaagggc atgacgccga ccagattttc tctgctcgcc agtaacccta
     8221 caaacgcagc aaactggaaa agtatcagaa acagcgttgc aggaaacaca atctgccaga
     8281 atagtcgctg ggaaattaaa cggctatcac catgtgaaac gttgttacgc cggggggtaa
     8341 aaaccctgta accgccccaa cagagaatga taatgataat aaaattagcc gttaatgaga
     8401 gcgtttcgta aaaacccagc tctgcatatt tgcggacaaa aatccctaag gcgatccctg
     8461 gcaatgccgc ccagctgaaa aacatcatca tgctgatcat cagtgccagt ggcagataaa
     8521 agagaaaaac ttcaccggaa gaaatatgcg cgaaagtatt aatgtgggcg aaaatgggca
     8581 agattaaaga aggcaggaac agcggaagcc cccaccattt atcacgtatt tttatataag
     8641 ttgcattcag tttcatagat gctcagcaga atcccccaca tcctgaagga ggtgtattca
     8701 gacaggcatc ccacctgact tcgaatgatg attattcatc actatagaga gcaatgattc
     8761 taagtgtcat atgaaagttc caattgatat atatcaaaca aaataaccct gattaatgaa
     8821 ttattacgtt tatcatgtta actcatcatt attacatcat cattgtaaat aattaaatta
     8881 acttccataa cattaaaata tgtattcact gacgcttctt tacataacga agaattgacc
     8941 attttgtcct gttgtgcctt aatgtaagta ccgtccacgg cgtgggacat acttcaagga
     9001 accttttgtg agtcaggcaa ccagtatgcg aaaacgacac cgatttaaca gtcgcatgac
     9061 ccgtatcgta ctgctcatca gctttatctt cttctttggc cgttttatct actcgtccgt
     9121 cggtgcctgg cagcaccatc agagcaaaaa agaagctcag caatccacac tctccgtcga
     9181 atcaccggta caacgttagc ggttaccttc tccactctca cagaacataa cggcacctcg
     9241 ctgtcggatg cttttgctct ttgagattat caaagcggca gatattcttt catcttaaat
     9301 tttacgtctt tgttctgact gcagttcggc tgcgaaataa atacatcatt aatacatatg
     9361 ttgtgatgat gtatttttat aaattattcc ccacatgaat tttaataaat ttaatctatt
     9421 cctttatacg caatacattt actttcctct tttgatgatc ttaaatgtct tatttttcgt
     9481 aatgtgtata acaaggaata gtgatgaaat ttaaaaaatg tcttctgcct gtggcaatgt
     9541 tagcgtcatt cactctggca ggatgccagt caaatgctga tgatcatgcc gccgatgttt
     9601 atcaaaccga tcaactgaat accaaacaag aaactaaaac cgttaatatt atttccattc
     9661 ttcccgcaaa agttgccgta gacaacgccc aaaataaacg gaacgcacaa gccttcggcg
     9721 cgcttattgg cgctgtcgct ggcggtgtta tcggccacaa cgtcgggtct ggcagcaatt
     9781 ccggaacgac ggcaggtgca gttggcggcg gagctgtagg cgcggcagcg ggttctatgg
     9841 tgaatgataa aaccttagtg gaaggtgttt ctttaacata taaggaaggc accaaagtgt
     9901 atacctccac ccaagtgggt aaagagtgcc agtttacgac aggtttagcc gttgttatta
     9961 ccacgacgta taacgaaacg cgtattcagc caaataccaa atgtcctgaa aagagctaat
    10021 aatcaggagg agtcatgaag aaagtttttc tttgcgccat cttagcctcc ttaagctatc
    10081 cggctatcgc ctcatcattg caggatcaac tctcggctgt cgcagaagcg gaacagcaag
    10141 gtaaaaatga agagcaaagg cagcatgacg aatgggtcgc ggagcgcaac agggaaatcc
    10201 agcaagagaa gcaacgtcgc gcaaacgccc aggccgcggc taataaaaga gcggcaacgg
    10261 cagcagcgaa taagaaagct cgtcaggata aactggacgc cgaagccact gcggacaaaa
    10321 aacgcgatca aagttatgaa gatgagctac gtagcttaga gattcagaaa caaaaactgg
    10381 cgctggcgaa agaagaagcc cgcgttaagc gcgaaaacga atttatcgat caggaactga
    10441 agcacaaagc tgcgcaaacc gatgtggtgc aatctgaagc tgacgcaaac agaaatatga
    10501 ctgaaggcgg tcgcgatctg atgaaaagcg tgggtaaagc agaagagaat aaatcagata
    10561 gctggtttaa ctaaacgatg ttagtaactt caaacctata attctttagg ataaaaaacc
    10621 ctctgtagta acagagggtt ttgttcattc atagtgcagg gtcaaatcat tcccactcaa
    10681 ttatttacgg catgcataac caattgactg gtaacaactt tctgtaacct gattttcacc
    10741 gtaccgtttt atataccgtc accggaaatc agtgccacga tttttgcttc ttcagtgaat
    10801 cgtattgctg ctcgcagaat tcccctgcga tacgatactt ttcagcctca gctgctgttg
    10861 cgttgtaaac tcggttgctt tcttcaagca tgtcggcgag cacaccgatg accttgctgg
    10921 ctggcgtgcc aggggggaaa gatccggtat agtgttcggc gagccgcctg gttttgtcaa
    10981 gctcggcgcg catgctgtca gcagcggaat tagcatactc agcatcagca cgcgccgcat
    11041 cgatacggga ttgtgcttca cgttcaattt gtgttttctc ctgctcacgc tgtgacctta
    11101 acttatcatc agcctgtttc tgatcttcct tcgcctgagc atacccggca tcgtactggc
    11161 ggctgccatg cacattccag gcaacaactc ctgatatgac cagaacagca agcatcgcca
    11221 tgacaaccaa ctgtttccgg tatgcttttg cgaatgccca gatcataccg ccagcacctt
    11281 actggcagtg atgtaccgca cgcgccggtc gtcgatgcca ttcctgccac cattgataat
    11341 cagagttaca cgtgcaatat cgccggtata cttcatgcaa cctttgctgg agaagaacca
    11401 cgccgcgcta cgagccgcgt attcgtcctg cgccaacagt tcaggattct ccagcaggtc
    11461 cactttcagg ccgtttccgc aatcacgata gttattcaaa ccggtaatct ggataagtcc
    11521 gcggccacgg taattccagc catcaccaga ggcattgttc cccatgcgtt tgctgtacac
    11581 cagattggca atcgcacgct ggcgctcagg tggcaatggt ggctcgcctg cacgacgacc
    11641 caatgcgtta gcctgtccct gagtaagacg accggcacga acgaagttag ccagtccggt
    11701 gacgctgtaa ttgaaattct cctgcaacct ggtgaagcca ccagactcat gcccgacctg
    11761 agcaataaac attgcctgat cttcgggttt tctgatacca aactctttca tcgcagaagt
    11821 tatatgcgag aaccagcgtg cggccagagc ctcgctaata ccagcagctc gctggaattg
    11881 tttaatctcc atgtttagac ctcgatgttt tgaaaatctg aacaacgtta ccgcgtgttt
    11941 taataaccgc ggcaagcatg acagcgttga taatgacctc agataaatcc acagccattg
    12001 gcgtacgtaa ccagattgca taggcgacac gaacaggaat actggccgca gcaacaataa
    12061 ggaaataagc aagccaccct ccccatcttc gatgttgaga gccgttacgc cggaatgtga
    12121 caacgcgaat tgctatgcca gtacaaataa ttgcattggt gataagcaaa acaagctcat
    12181 tagttaccat cgccttttct cccaggaatt aactggcgtg gattatcaga acggtgatag
    12241 agccatatac caattcgcac tgcgacaatt gctgacacga atgcgccagc agagaaaaca
    12301 atccctttct cgaaagagtc ctgcgtgatg gtaggtatca tgctggctat tccgataaga
    12361 attgatgttg ttggtttgta aaagagaaga ccacaaagaa agctgagtat cgacaagagt
    12421 acacgacgac gaacaggata ctctacagca gaggtaacaa atattaccgc accagccaga
    12481 gcaccgagag ccacctctgg cggaacgccg tagacgacag aggccagcgc acccaagctt
    12541 aacccttgat tcagtgaatc cgccgtaacc gtgccattca tggtaaccac cgtttattgt
    12601 gcataaaaac ccccttagaa gatgaggtcc atcatacaca ataaaccatt tacggataat
    12661 aattacctaa atttggtctt attttgattc caatagttcg agtcgctctt caatacgatc
    12721 gcatcgacgg cgctgatatg cagcctcaag ccaagcgcac tggtcaggcc gtatacccca
    12781 tgaactaccc gcttttttaa ccagcctctg ttctccggtg tcatattcga cggtgaccaa
    12841 ctcaccagac gtatcggtaa tctctttagt cgcgattacc ggctcaaaaa tatcatccca
    12901 ctcgtcatag caaagaaggc caaatctggt tccatcaatt ccgtgcgcca agaatacatc
    12961 ccttacctgc tgagccatga cgccaaaatg ccatctggca ccatcgccct tcatggatat
    13021 agcgtcgagc catcgatacg ccacaacaga aatatcgccc caggcatcaa gaatgctgtc
    13081 tctatcagaa gaaagcattt cacttaaatc tgatattgcc tcgggattgg ttttcagcgt
    13141 ggcatctgat gaaacggttg gggcatttgc aaagtaggcg tctttaatac gaaacgatgc
    13201 ctgaccaaaa ttataggtat tgtcagcaaa cgggcgaaga cctgtatcat aaaaccgcca
    13261 gcgtatggtt cctcccaatg ctgtcgggtc gctgttgcat gcaatatcca ccgtggtggc
    13321 agacctaaac acagaagaac taccgcccaa taccaagcta tttgcgctag ctgtagcctg
    13381 ctggtcaagg accaatattt tctgagagtt tgtagttgca ccggcatatg atgatgcagt
    13441 gatgcggttt aattggtttg tatcaggatc tgcgttttgc tgaatggtta agttagatgc
    13501 ccactgtgcc ggtcgctggc gcacaaatac aaagtcacca gaaggattag ttgcaaccaa
    13561 ataactaatg ccactatcag atgaataata gttgactata aaagtctgat tattcgcatt
    13621 cagtatttca acatatgtgc tggaagggat tgccacgcca gatatatcag caatgctgac
    13681 agtccctgtg taaaaattaa atgccttctg actcatctcc tgcatatagc gaagaatttc
    13741 agtcatgtta gtgaacaacg taccatctac agggttaaca atccccttcg cactacgggg
    13801 atatacccca atgctcgcgt gatcgatatc aaatccgcgg taaagcctgg atgcaggtgt
    13861 aaaatcgata gcatctttat cagtggagaa atcttcgaaa ataaccaaac ctgaattgta
    13921 aggttcagag ccagttcttt cctgatgaat gtaaagtgaa taaatggatt ttccatcctg
    13981 agaaacacaa acgccttcat tttctatgcg agtgacgttc aatcctgcgg ctttcattaa
    14041 atccatcatg gcctgaggat gaagcattga ttcagttcgc tttgtaccgt cagggttaaa
    14101 aactttgctg ccctgatatt cgttatatcc tgcgcttcct gccccatcag ctatgaagcc
    14161 gccatagccg cagacaaagt agttatcacc taccgcaata ccctgacgct tgttgaaata
    14221 aggcgcataa ggtgaggtgc ttttagttac atacccaaca tcatgtaacg gcagcgttat
    14281 agttgacagg cgattgaaac cactgtcgaa cactgcaagt acagttcttg tgattttctg
    14341 tcctacttct ggcgcattct gctcaacgag ccatatacct cttctgtagc tgaactggtt
    14401 gaataatcca acatcatggt tttgtacaag aggcagattg cttccgtata atgccccctc
    14461 catattaaat tcacgcagta ttccgtttgt gtgaccaaca aacatttttt tggggccata
    14521 gtctgacgta accacgattc cttcagcagc gaagcctggg ccgccagcct gaacatagaa
    14581 ataaccttga taaataccag atatgttaaa tactgcgacg acattattcg tctgtttagg
    14641 ctcaaatgga taagtgatgt atatcaaatc ttcgctaacg cagaatcctt gaggatacat
    14701 ataagttgct gacgggttag cagccataat cgcatcatat tcaggaaaaa gaagcggcat
    14761 cgtagctaca atctttcttt ggtgatttgt aaaaatatcg tttttagcgc tgttaggtgt
    14821 aggcgttaca cctccagtaa aaagatcatc aacataacct ttattgacag catcgtttct
    14881 gtcagtggca tttgctagat ttgatatctt attatttttt gcatcataat agttagccag
    14941 aatgcttggt tttataagtg ctaacctcat ccatgaaaaa cacttttgaa taagcattgt
    15001 cagtttatcg aacgcgtctt catgtacctc agcgaagaac ttaccctgat tacgcaaatc
    15061 agtatcctgc gtaaccggga gctctcgtga tatagaaata tgataaccgt tagccaacgc
    15121 cttcgacaga attacattac cgccattata tcctccagca ttggttactg tgtagtcagt
    15181 atccagaacc aattctgtta cgttcccgtt caggtcagac acctgaacaa ccaggtcgga
    15241 ttttttgaaa atacggaagg tatacggaaa tgatgtcgta gctccgttac cggtgtattc
    15301 gttgtggtca acttcggttg agaccgtcat gttaaatctc cagatagtcg cagcacccgt
    15361 tgcgccgcat atctggttat tctattacct ggaaaaccac atatggatag aaaggctgta
    15421 aatacgaata gatattacct ttcaggtaat ttgcaaaacg tgctggatag caaacaaatt
    15481 atttgctact gtataaatat acagttattg catggagaag ataagatgca gcagtatcac
    15541 tatccactgg aagacggatt taccgaaagg attcacacgc cgggaggcgt caggtcactg
    15601 gtggagggat cgcacttgat gaaattactc cgggatctcg ataaggatgg atttaatgtc
    15661 gatggcccac ttgccgaact gactgcactg attaactacg tcaccagctc acagatgtct
    15721 atgcaggatc tgcaaacaca tctcgactat tgtgccgaac aattacgaaa acaaaccaca
    15781 taaagaaaag gccgcgaaag cggccattaa cagtcgtaaa attctgggtc ccacaaactt
    15841 gcatcgcgcg gcatggattc taactttttc agccgcaaaa ttctgtcaca ctcgacaact
    15901 aatttttgct tctgctcgtc aatttctact gtcttatgcg ctggttcatc ccaataatcc
    15961 agaaggaagg catggcgttc agatgtgacc agataaatca catacacgtc actggttggg
    16021 atctttttat gcttgttagt ggtcttgtct ttcttcccag acgcccagtt tttccagcat
    16081 tgttccgtac cgctctcacc aaacttgtca gtatagtttc cgatgtttaa gtgaacgtgg
    16141 cgtatgtgat attccagcat ctctttcggt ggatctcgaa acagagtgtc ctttccgaaa
    16201 tccttatgat gaccgtagcg ccagtgatct atgaacgcgt ttttgatagg tattagctca
    16261 gggtccttcc caaaaattcc agggtgaacc aacccctgga atttattcgg catcgtcgta
    16321 gagctcctga gccatgtctt cagcagtgcg tgcaaacatc ctgcgcgaga ttgcatggga
    16381 tttctctacg gacatctttg ggacctcatg cataacaagt tgatgagttt tctcatcaac
    16441 ttgaagtggc ttgtataaac gttgccacct ttcgttaatt ttatccttaa agccagcgaa
    16501 accactttcc tgactcttgt atccaaaatg agataaagcc aaattccttt ccatttcatt
    16561 cctaatgtac tcagcaaggt tgcagtggaa tacttcccct tgttttttta ggcatgcttc
    16621 atggtctgta acactgtgac ggctctcata taagtaaatg cgataggaat ttttattatc
    16681 ctcttcttca taatttctaa tcgcatcagc agttgccata gctgcagcat aagcggctgc
    16741 ttcaatcacc atctcttgct ctttttcttt ttcaggcctt ttcaaggcaa agcgtctatg
    16801 cctcatcgct gtaactctct tcgtgttcat gggcaccccc aactaccttt agggtaaaca
    16861 ttctatcgaa agtatacgct cactggcaaa aaaataggca ggtattttct gaaatgggat
    16921 caatcaaacc acatagggtt gaaatgacgt gagttatgca tttatcatta cctttgcggt
    16981 aaatttacat tgcactcctc ttgtgccata gtaatcgggc actggcaaaa tccagtgccg
    17041 ggattggcgt tccggattac taaaaggcgc attcaccgcg caagcggttt ttttatgcgt
    17101 atagcacggc cacattcgta ttatggtggg ctgtgtgggg gcaccgaaag gtgcgccggg
    17161 tccttttagc cggttacgcc aaccctgcac agttcaccac caaccgattg gcgtcggtag
    17221 tggtgattaa ccagactaaa aggtaaccac tatgacagct acaaaaagca cgtccatttt
    17281 ttctttcgaa tcccaagccg atatacgagt aatcgtcata aatggtgagc catggtttat
    17341 cgcttcagat gtttgtcggg ctataggcat agcaaaccat cgagatgctg ttcgaaaact
    17401 tgatgatgat gagaagggcg tcgcttcaac cgacacccct ggcggtgagc aagaatcgat
    17461 catcatctcc gagtcaggcc tctacacact gatcctccgc tgccgcgacg cagtgacacc
    17521 aggcactatc ccctaccgct ttcgtaaatg ggttacaggt gaggttcttc ctcagatccg
    17581 ccgcaccgga agttacatta aaaactcgct cccgcaggaa gaacgcataa agatggttgc
    17641 cgaccaggta gccaacgcca cagcatcagc agtgatgcag gcaatgaaga tagagaacaa
    17701 aacctacagc gccccactga agcccggcta ccgcagtttg attcactcgc cgtctggtgt
    17761 tctcggcctg acggagaact cactgctgat gaatctgctg aaccagttac aggaagacgg
    17821 gcacgacgta tcgggcgcgg cggcggagct gaccaccatg ttctgctaca tcgtcggtgt
    17881 gagcaaatgc ctgcgtgata tccagaccca cgcggagtac atcaacgaca aggcagggtt
    17941 cttctgacga gcggcggcac agggatgtgc ctttaaaata atcattggcg atgtgatgta
    18001 gattcgcgta atattacctt aaaggtaaac ctgtttttat tttatacctg taacttaccg
    18061 gagattaaag atgacaaaac ttggattcgt gatgagaggt ccggtaagaa gcggaactca
    18121 tgcaaagcgt agcaagagtc gtatttttac tggtaaggtt gtagcacgta aatcagctat
    18181 tggctcgttc aatagtgaaa atgcggcatt gcgccatatt tttatcagca caaagccaag
    18241 agcatccgct gatgtgcata caatgtctat tcctatcaca aagaatataa agcggataaa
    18301 aaagctctca tctgcagaat caaaagagat atctttccgc cagcttaact cattagaaac
    18361 gcatatgaag gaagaggaat tcgatgtttt tgagtgagta tagcgggaag gttataccta
    18421 ctggtgagtt taaaactgat gactttctga tttcgctaaa agatgctttt aaacaacact
    18481 ggcgtcatgg tcatcatcct gatctgggaa aagatactct ttttgaaaga ccagacgaag
    18541 tattaggctt ccatctcaga aaggttcatg tcaatattgg tgaatatgca tcatattcat
    18601 actcatgtac tgaacagtgt tgggatgagt ggtcatatgg attgattgat gaacaaggaa
    18661 attacaggcc aaaaccaacc agtaacgcat atctcatata tgcagtcaat gaaataagag
    18721 atgcagcctt actagcttat tgggacccgc ccgcacacac caaagctaac gcaaaagttt
    18781 ggatggattc cgtattgaat ttcacaaaat tatttcatga acgaacgaat acagctccac
    18841 ttagtagaaa tgtttatccg tgggattatt cgtacaaatc caaaaagcct gcatagtagt
    18901 tttttatgga cgaaacaaaa gtcagtgcta cactcattga cgccacattg aggtggttta
    18961 tagatggaaa tttcacaatg aaaaaagcat ttgctgcact gttcgttttg ttgtctctgg
    19021 tagcttcaac tcaggccttt gccggtcgtt gtcagcacga cagcgatact gccgctgacg
    19081 gctcccgctg cggtgggcgt tctgcggatt cccgcccggg tggcggtggc attcgttaaa
    19141 aacaaggccg cgaaagcggc ctgtgacatg tcacgcaacg caattattac cgcgccatgt
    19201 aacattttta ataatcttat cagcaccaaa ctcaacgtaa acagagcaac tgaaatggag
    19261 tgtataaccg ccatcagttg ttgcgtatgt gtttgaatat atagtattac caattagatt
    19321 agacgtagta ttatacgttg tggtttgtgg tacgttataa ctatcagagc ttgagtaaac
    19381 atacactctg tttccatctg gagatgtaag ctctccctga ggataccccc actgctgaac
    19441 cattgcgtct atactctgcc cgcgccacgt aagcatattt ctttcaaact gtgcagctga
    19501 ctggcatcca acgagaagca taaatccaaa aatcaaaaat acttttctca taattacccc
    19561 tatcatggaa aaacagcacc aatccacaaa ttaactagtt attttattat tcttccgaac
    19621 aatacaattc cgaatactac aaagccgaac catgccgctg cacgcaacag agattccaat
    19681 tgaaacccat ttttatcaaa atgtatgaat agcataaaaa cgctgcacat attagtacaa
    19741 taaaagttat ttgaaccatc atatctcctt ttattgcgga gtgacatcct gtggtcgcca
    19801 ccagtatgtc tggttaaact ctttcttcga acgttgctcc attttacgca aatagcctgg
    19861 tgaaaaatac tcctgcatct ggttaaagat catgtgatcg agagccgcct tcaagtacca
    19921 gagattcgca cctggcatca gacctttccc cagcttgacc agatcaccac cagtctgctc
    19981 attcttccct tccacagcat ttagaggtat gccctgagct atcttcacta cgtcatcaac
    20041 cagaccagct accgggccaa gcatcgacgc cagcgcgccg ctcccgtacc tagtgtggtc
    20101 agagaagaga aaatcaccgt acaaccctgc cccaccacct tttaaaaatg catttatcca
    20161 gaatttaacc atgtggtcac cggtcatttc ctttggattt ctcccattaa taagatcagt
    20221 aatctgcatg gaaagagcac caagcatggt tgtgcttgct aaaaacgttg ctatatatgc
    20281 cgcacgccca ccagcagacg acatccccat agctctatgc cagtgacgca taaccaccga
    20341 gatagggaac gatttaaaca ggaaaacact tctcgttaat tcacctttcc atgttccacg
    20401 ctgaatacca gaaccggtta tcagttgctc acgtgctccc ggtgtaataa cagccatatc
    20461 aacttcttca gttacggcac cgagcagttt acgcattgcc tcaaatttca cgcgttcagg
    20521 ctcaccaaga tgtttaactg ctgaatcagg gatacgcata atgctttccg gtgtcagcat
    20581 cgtattatta ccgttccccc agtcctcctg ttgcgccagc ttccatacgc tccagtctgt
    20641 gtcagtaatc cctttgcttt tcaggatacg aaaatcagag tcatcgaggc tacgaaggtc
    20701 tggtgtccgt gacactactt ctcccaggct tcccatcatg gttacgccat aggcgcgctt
    20761 gtgcgcatct gaccatgctg taagcccact ggcacgcatt accgccgttg ccgcccaacg
    20821 agacactgac ggccccatat tatccatcgc ccagcggtta acgctgccaa gtagagattc
    20881 catcgccaga ccagcgcggc gcgcccgcgc aagttctgta cggttcgttg ggtccatagc
    20941 ttcaagctgg ttgcggaata actggttcat tggaaggttg gtaaccttcg cagacagata
    21001 catggttcca agatcagaga acgatgacag caacgcggat ccgagtctgc tggcaaccag
    21061 ccagttgcgg atattgtcag accatcgcgc gatgtgcgga ttcgctacag gctgtgtctt
    21121 tccggaaata aagttgtaca gattctctgt gttgttcgcc agccgctcga ctttaccggt
    21181 tttactaggg ttagctgttg ccgtttctgc cttaacctga tcaagaaggg agcggaaaac
    21241 atgatcgggg tttggaccat atgtttccac cagagcaata tctttactga taccttccag
    21301 gtgaccgacc atgatttccc atagagagcg atcaccataa agttgttgat attggagata
    21361 ggaatctgca tctttgaaat gtatctgtcg tgatgcatta ccacggttag cacgtgcgcc
    21421 ggaaattcgc attccggtat cagtaagctt attcagccca ccagtagcta tcgtgttata
    21481 agcctctcca agaaatgcag acaactcggc atcgttcatc agttgtccat cggctcgggt
    21541 ataatatttg cgatccagct tacctataac atcgccaacc cacttatcct ttgataccgc
    21601 cccaaccttt tccatagaat gatgttgagg gatcccccag ttttcgagat agccaatgtc
    21661 cccaccagca tcattaaacc ggcggcgcag cagctctgta acttctctcc acgccttagc
    21721 accttttctt gctttagcat tgccagtatt ttgccctcgc atttcatata ccaggtcacg
    21781 cacgccagct tcatcttcaa acaggccaaa aaagcgagga tcaactgctt caaatgcctc
    21841 ttgcaattga ctcaatgcat aatcacgagt ggcttttgtt ctggactcaa cagagaggaa
    21901 attcgattta ccgtctgcat taaaagcaat agtacggtta agagcgccaa gtttcccatc
    21961 agccccttga tagctattga taaatttatc caatctctga cgtgcggcta tagtgagggc
    22021 cacacgacgt ttctttaatg ccgcttctcg ctgtaattct tcagatgcca attgtgctgc
    22081 acgatatagc cgctctgatt cggaaagttg tctccacgac atcgggtcat cacgagcaat
    22141 ggagcgcata tttcgataaa tgcggtcttc aatgttctgt atttctcgcg ccgttaacgt
    22201 gcgctgcgcc gcctgctgga ccgcttgtat acattcctgt ctcatttaat ttaacctctc
    22261 aagaaacacg ccacagctac atcaaacagg cttgaatcct gtattgcctg ctcactttcc
    22321 ctgttcgctt catccagtac ttcacgcgcg ctgcgcgatt gtggattacc atcatcatcc
    22381 agcacggtga ttatcatgtc aggtgattca agcagcgagt cttcagctat gcgcagatca
    22441 atatctcccg cctgatccgc catcattttt tgttctgcct gttgcaatat tttatcaggc
    22501 tcaaaaggag ctacttcgtc tggcgtcctg acctctgctg ttttatagaa tgaaacagcc
    22561 tgagcattaa gttcactttc tgcctgctgt ctccgagcca gttctgctcg agcttcaaaa
    22621 aactgaccgc caggctcgtg cggtgccaac gcgttacggg aaaattccag gcgttcttgt
    22681 gcctgccgga ttcgttgatc aatatcgcga agtctggcct gtttatctga tcgagcacga
    22741 gacaaagctt taccgctacc ggttggatct tctgcaagaa tttgtgcacg ctgttcagtg
    22801 agattttcaa taattcgttg gctattagcg atttcagact ggtaaacctg tctatctcca
    22861 cgcggcaaaa gctgcgcggc ctgttcttca agcaaccgat tttctataga gcgcgccgtt
    22921 actccatcat ctacagatga cagagcctca ttaactgcct gagacagcag actcttgcgc
    22981 ccaggaattt cactgaaaga tgcagactca acaatgctgg caacgtctac aggtctccct
    23041 tggctaacat cagacatagc ttttcgcaga gcctgaatgt gagaattgcg cgaaagcacg
    23101 ttgatcggca cgccgggcgc aatatcaatt tcagcatgat gagcggcatt cgccgccagt
    23161 gcagcatcaa catcaacttg tgaaaaattt ggtgcgcttg tagactcgcc gcgagagtta
    23221 ataaatctgc cgacaccacc aaacgccacc ccaagaacag catcaatagc aattgcctgt
    23281 cgatccaaca catcatactg gttagccatt tcgctatagc caccatcacg aagcgttttt
    23341 gcagtaagcc cacgctgtgc cataccgaac gcaatatttg tacctgcggc ataggcaata
    23401 tctggcgttg cacgtactgc tgttgctgcg gcgcgtcgca ctgaactctc acccgtccgc
    23461 gcaagctgag ccgccacacc ttccgccagc gcaccaccag cacgtaaccc gaggctcata
    23521 gggatcagtg ttccggcacc agcagtaatg ccctgcacta atcccgcttc ctgcgccgtc
    23581 ctgaaatcaa caccctgtgc tgtcagccgt tcaaactcag aaaaaccctg tagcgaagtt
    23641 accgccgctg cacctccgac aggaccaccg agcgttgtac cgacaacagc ctgcccgccc
    23701 atatcgaaca acccataaag aacctgcccg gcggttccgg ttgtcgcggc atcaggcgtc
    23761 agccgcttaa cctgctgctc tgctagtttt ctctgctcgg caatgtatga aactgaagtg
    23821 tcattgagcg aggtgttttc gttaacaaac tgagcaatcg gggatacgat tttatccatc
    23881 cctgcccaga gcaactgatc tggctttgcc accagcccgg agtacaaacc agacaatgcc
    23941 gctcctacag cattgtcgaa aaaaccaaca tcgctgttaa agccagctgg atttgatgct
    24001 gcttcgtcaa gctgctgatt ctggtttact ggattaaggc caaagtaact cattgcggaa
    24061 tatctccgga gaatctctga cgcttctgtg tcagatcaag aacaacggga gaaccatcat
    24121 cttttagcag ataaccagta ccaagtttca ccaggtactg actatcgccg taactttgca
    24181 aaccatactg accaggcggt gtttttatcc ctgtgccaac aacttgttca ttccaaacct
    24241 gattaacctg cttatcgaat tgctctgcag acattcccca aggcaaaaga acattcccca
    24301 ttccgttata gtcatgcacg ccacctgtag ctacgttaac agcctgtttc cagatatcat
    24361 tgtcaatttc gcctgatacc acgccttttt tcgccatcac accagcgtaa tagtcctttg
    24421 cgatctcgta tgccattgat gccccctgag catcaccagc aaatgcatcc ttcaccatgt
    24481 cagaaaactc aaggcgaaga tcagcatctt taggcatcgg aatacctttc gcgtcatcag
    24541 tacctttacg agccgccgcg ccagcaagaa ttgtctgcgc agcggtttca ggagacacgg
    24601 aaacatccgg attaaaccag tttttttctg ccaaaatacc acctggctta tccatcagta
    24661 tcccggcaac ggcagcagat ggagcgttgg cactgatctg ctgtagtgct gacatataca
    24721 cctgcccacc accagtgctc tgcctgatgg tatcgagata tgctgcctgt tgggaaacgg
    24781 gcgcatcacg aaagaaaaca ccgatctgat tggcctcgtc tttggaaaag aacgtcagtg
    24841 gagtgccata tgacttagca aggtcactga cctgagcagc acgcaaggca acgctctgtc
    24901 caaagttatc cttattgctc atgtcgatag gctttgcctg tccggcggca agagagaact
    24961 gtacaggatc agcctgtcgc tgctttatca cctgacttgc agccgacaca acgttgtcat
    25021 aaagagcggc tcgtgccgca taaccctccc ctgtctcacc agtatccggg cgtaattgct
    25081 caacatatgc tgtaatgctg cttgtcggca tgttgcggaa agagcctata tactgtccgg
    25141 cgatttgcgt atttctgaac tcggtatatc gcaggtttcc ttctctgact ccataagctg
    25201 caataaaatc agcctcacca ggtgggttag gaaattcaac gccacgcata tacgcagctg
    25261 tcgcatcgcg aacttggctg tcaatcatcg ttttatattc agcctgctgc tgccgacgca
    25321 gttgatccgc ctgtcgcata aaacttgcct gcgcctcagg agatgccgca tcgaatgctg
    25381 cattaccggt atagcgtttg gtgttggttg gaattgttga taaaccaagt gctgcactga
    25441 caccagcact taacagctga tcactgtatg gctggctacc gttctcatga tggataatgg
    25501 ctgcacaaag cgccttcagg gtatcaggat tagatgcatc gagaggctca tcagcagaaa
    25561 cgccaagttg ttcgcacact gctttgatat acgacatagt gtcattttta tcagtaggcg
    25621 gtgcccagcg attaattatc tcgctgacgg tatcaatacc ctgcctctga tacgacatca
    25681 ggttccgccc taatgcacga atcccgtgtt caggtgtttc gaatttagca aatcgaccat
    25741 catcaccggt ctggcctacc cacggattgg ttttgctgta ttcgagattt cctgggttat
    25801 tgttgcgtat gccacgggca cgctcggaag aatcactatc tgctacagca cggctagctc
    25861 cagcagcagt atcacttaac tcgccattac tttggatgaa tgcggtcgca ttgtttgccg
    25921 accactggga caatgctgca tcagcaacct tctctttaaa ctcgattttc ttggcctgga
    25981 tttgctcgtc gctccagcca tgcgcaatgc cgtaatcctc aatttgctgg aaagtttgct
    26041 tattagccaa tacgtatgcg gcgttgtcgc catacaatgc tgcggcattt ttaccattgt
    26101 tcagcagcgt cgcctgaaac tggccttctt cgtaggcatt tatttgccct atctcgtgcc
    26161 gcccggcctg cgtagtgaac tgaatgcgct gctgctgcgc ctgctgcatg aaagcattac
    26221 gagcctgttc atccggcagc gacatagcca gttgctcgac ctgggcatca aactgctgcg
    26281 tatactcctg accttttcca atagcatttt tccctttcag gttaagcaaa cctgtttcag
    26341 ggttattcag cagatcgctg cttatctggc ttaagctaag agaagcatcc tgagccatag
    26401 caacattcgc acgctgtttt gcctgcgcaa taatacctgc atattgctct gcaacatcgc
    26461 caagtacatc accgacattt ggcgtctgaa acgatgagaa tccctgcgtc gaaatccctc
    26521 tgctctgaac ctgacggccc gatgttgttg gtacaactgg catcttatta tccccttatc
    26581 gaccggttgg agtgccaaca gcagcagaaa tcggcgcagc cttctgagag aatgggctcc
    26641 acgttcctcc gcccatctgg tatgcaccgt atgcttttag tggtgctgtt aacaaagtgc
    26701 tggtcatcga tgatttagca gccgactgag cagcagcccc ctgtgcctga gcattcattc
    26761 cctgaacctg atacccatat gcctcacgct gagcattatt cactgtcgtt aacgcatcaa
    26821 gagcgccgaa ctgagcatta tccgcaaaaa cgtcaagagc tgttccgcta cttaattccg
    26881 caccggtagc ccccatagtg gccgccgcag tgcctgagcg ttgacgcatt tcacgacgac
    26941 gctgatccgc ttcaatattc ccacgattga ttgaatcctg tgcctgagct tcagcaattt
    27001 cagcattccg atcagctatg gctgactggt attttgcctg cttgctctgg ctgtacattg
    27061 acgcggctgt ggatgccact gtgacggcaa ccaaagcgat ggctgggtta cacattattt
    27121 tctctccatg tgaaatctgt ggaaattaag accaagagca ccataaggcg cggcttcttc
    27181 aagcctgaat ccaagccagt ggagccatgc tttggcaaca tggtttcgct cgtcgacgta
    27241 gttttccaga cgcggataaa ctgccagcat ctgctgcaat acagggcggc agtggcgaag
    27301 aaatgtcttc tgatattttt caatacggct ggttcctacc agccatggcg taccattgcc
    27361 accgatcatt gacgccggag atacgccaaa catggttacc agttctccgt tcgcaaatcc
    27421 tgaccaggcc atagtcgcag tacgcagacc aacacgcagc gcatcttcgg tagtcatcag
    27481 tgataccgca tacagttcgt caatatcagc ctgacgaaca tccggcaaaa tcatctgaag
    27541 atgctcttcg gttgcgggaa taatttgaac atcgatcatc agaatccccc aacagtaagg
    27601 cgaggaataa cggcaagaac agacagcggc aacggatcaa gctgacggat ttttacacgt
    27661 ccgtttttgc cccagttact gtccagtttc acttctactt ttccggtagc atcatcaaca
    27721 ggatcatcgt agaactcgaa ttcacgctgt ggatattcgt accatttacc gccgggcgta
    27781 gtcgcccaga tgccgcgact ggcattcaca accagagtaa cggaggggat cacctgtttt
    27841 ttgtccagca gcgtttcctg tccgttaatg ttgatatcca gtgtttcgaa ttcagcagtt
    27901 attggcaggc cgatgtgcac tacagccccc ggagattcca gcgtgacggc acctccggaa
    27961 accactttct gtggttccac gttcgcatca gagagaatgt ttacggtctg gccttcaaga
    28021 tgagacaggc ctccaaatgt ccggcgcgcc atctgccagt tcgtggtggc cacattcctg
    28081 agggatggcg ggacgttcct gttagcacga accactacag cggtattgct ggttacagaa
    28141 ataatgtcgc aacgtaattc ttttgacact tcatcgccag tatcaggatc agttccggta
    28201 taagggaaag ggaactgtag ttgggcaccg atatcactac tggtgaagta cgcaccacca
    28261 gaaacactga ttgtatattc ctcgcggtaa tcccattcgc cagaaccacc agtgatgatc
    28321 atcgttctgt cagacgtatt tcttccatca tagctaaggc cagaatcaac aaagaaagca
    28381 tcttcatcgc tggtaaataa acggctggac agtcgctcga tgtatctcac tgtttgcccg
    28441 ttaacggttc ggttaacgac gaaatacacc gcatcttcat ttccttcgct gatactgcat
    28501 gtgctttcat attttccggt actggattgt ggtgcccatg caaaaacctg ctgatcacgc
    28561 aaataggtca tcaccagtaa tttaccgtca tcacgaatgc agaaggcgct ggagtaaggg
    28621 actatcgaga agcaccagtc aacaatgctg tgcttctgaa aaagatgatt ggcaaggatg
    28681 gtcaggtcgt tcccctgata gccgtcaaca tcgaatgagt aggccagatc acggacaaca
    28741 ctgcctttct cttggacgaa cagagcaata ttcgccacgg caattggtgg gacattgctc
    28801 gagccatttg atccctgaga gctgaatgca aatgatgatg gggtaagcac tttgttctgg
    28861 tcgccagtga tgacgtactc acctccggaa gtcagcgcca ccagcgaacc aacatcaatc
    28921 aggtggcgga tctcattaac ctgacgcccg gcataggtgt agataattct gtcgtcatcc
    28981 tgcgtaggat tgcttttgcc aaaatcctta taatccccgg tacggctggc ccagatagtc
    29041 tgaggaaacg cagtcgatgc ggcgaagtaa agacgttgtt gataataaac aacagtgcca
    29101 ggataaccat taacactgtt ccaggcatat ttagcccatt tatagctggc attatcctcg
    29161 ccaactacct gcgaagggat ataggaaatc acctcggcag ttgcagtagt tccatttgca
    29221 gcagagatac gggcaatgcc aaaaccactg tgcagatact cccactcaat gccggtatca
    29281 tcatcaccgg atccgcccca gccatcccat gatgtgcctt ctgtatgcga agggcgcaaa
    29341 gtgcctgttt tgcctactgt aacggcgcga tagtagttac tgtctgcacg gcgaatatcg
    29401 ccaattgacg tactcttact ggtttcccat accggcacag aatccactgc aggctgttcc
    29461 agatagaaca atttgcctac ctgctccgcg ccaaaaatag aggcgcttgc cgttaacgta
    29521 attgtcccgg tgctggcgct ggcataaacc gtcactgact cgtcaatatt gatatcttca
    29581 aatggtccgt tcttcgttac cacatcaacc agttgccagt tgtcatgcgc atagcgacgc
    29641 aactctttcg gcgggtatgc cggatgaaca agcgtaagca cgtcggcgct ttgcgtgaat
    29701 ttaattcgga acagatcggc ttcagtatat ggcgtggcaa tttcataaat aacattgctg
    29761 ctgttcagca ccaacgcacc atctttgata acgcgcatgt actggtgtcc gaactccaga
    29821 gcataggtct gaaccgtcga gaactggaac gggatcaggc ggcatttccg atttgggtat
    29881 ttggcggcac cgacaaaacg cgtacctggt cgattctcaa cgccgccata ctgccgcacg
    29941 ataaagttat cgcacttgcg caatgccacc tggtacttcg ccatgtcaat acgcccgtac
    30001 aacgacggtc caatctcacc accggcaaag ctgggctgga tccaactgat agccatcagg
    30061 acaacctcgc aatggtaaac tcgtcaaccg gtggctgtgg ttcctgtgat tcattctggc
    30121 tatgcgagcc agcactaaga atcacgcgat tgtacatatt gagagcaaat gtaccgagat
    30181 ccgcattccc agtcagcgcc atgttaatgg ctgccgcaag acgccaggcc agcgcctcca
    30241 taaaaatggc atcaaacatg tttacatctg aaacgcgaga gacatacttg agccatgcct
    30301 gcggctggtc tgtgtagatc aattttcctg ttccgttggt gtctgcacca acttcgtact
    30361 gaacgcgcat tgctgctgtt ggattgcgta caccaggaag cataatttca gtaatgcgca
    30421 gacaatctga cgggtactgg tacgcatatt cccagtcagg cggtggattg ctcgtatctg
    30481 caagcgccac gcgtttggta gcaaagttcc agtcaaaatc agaaagcaca gcatcacggc
    30541 aggcctcaaa gtgcagcgaa cattcccccg cttccttgct ggcttccgtc aggctgttaa
    30601 tgctgcggct gttgccaata ttggacagcg cacgattgca gatctctact acagaggcca
    30661 taagtttcta tactcctgca ataaaggggc cgaagcccct tgtctgattc gcgaggctta
    30721 cacgcccagt tctttacgct tatctgcgat cttctcgcgt agcgtttcgg ctttggcgtt
    30781 atggtgtggc ttctcgttaa agagcaattc gtactcttca cggagcttat ccagttcacc
    30841 atcatctgac acatcgttga tgattttggt gctggttgct gccattgaca cctttcctgc
    30901 aacttttgct tttgcctgtc tggctgcatc gttaacaggt tccagtgcgc taccaggctc
    30961 accttcgtat tcgatttctg ccccctccgg ccacagagtg ttatggatat gagagaggcg
    31021 cagaacgcgg tatcttggtt tctcacctga catcgatatc accttaacca gttacttttg
    31081 agcggatcgg gtacggcgta ttggcatcaa catccagact gatacccgca gtgaatttgc
    31141 cagccgttag tgggccagtt gcgacggagt agttaacacg cagatatcgc tgaacaccgg
    31201 caggcacctt tgcagaaaca actcgtttac ctgctgtcag ggcggtcttt gccagtgcgc
    31261 cactatcata aatagtggtc catgagctgt tattctcact cgtctgcaac tggatgttta
    31321 cagttgcatc accgcttgcc gcggcggctg cgttaaccag cgcccaaaac tcaagcgggt
    31381 aacccacgcc gatatcacga cgttttccgt caattggacc gagatcgatt acgtcagtag
    31441 aagccgcggt attcgtaacc gcctgagctt cggagaacat caacagtttg tcggtgatca
    31501 tcttctttct ccattagtgg gtctgttacg acccacaggt taataacagg cgttacacca
    31561 cgcgggcttc tgtttccaga agcgcatcag tttcacggat tggtacacca cggaatgaag
    31621 tccaccactc gccttctgtc tcttttacgc tgatagccag agatgttttc tccagagact
    31681 gcagatcaag agcctggcct acagtgcggt tcatgtagaa caccgggcgg cccatgccac
    31741 ggtttggaat gcgatgtagt gctttaacca tcaacttcgc aatatttgcg gcagaggatg
    31801 gttctgaaag attgctgaca tcgatgtttg caatgcgaac aacataacgc cagtcacgca
    31861 gagcaagtcc gttgtcccat ttgtaatggg tacggtagcc ttcgtacttg ccgccattag
    31921 catcttccag tgtcacctgg cctttatctt ccatctggat gccagccttc tgccctttcg
    31981 ggaagatgcc atgcacggtg ttttcgcccc acaccactaa ccagattgag gtgttatctg
    32041 tacccgtgcc accagcatca atgatgttct gagcattacc cgcagacagg ctggaatagc
    32101 gggaggacag tcccataaac tgctgagggt taacgctgga atcaccataa aacagtgtct
    32161 gcgccatctg ctgattcatc gcttcaataa atgcgcggtc ttcagacagg cggaattcgg
    32221 cagtattacc gttcagatca gccagtgact tatcgacttc agcataggtt tccagcatgc
    32281 caacggaatc ggttacctgc actgtggttg atttgcttgg ctgtacgcca tagttcagca
    32341 aacgccaggt agctgaaggt aaaccagaac gaatggtggt tcggtgtccg gtaggaaggt
    32401 tcccttcgac aaaaggcata tcctgaagga tcgggttagt ttgaccgaga agctcgataa
    32461 tcttatcgac tttcccgttt ggatcgacgc gcttacccca gtcagccagc gttagcgcag
    32521 ttaagccttt aacagccatt gtcatttcct ctcttatttg ccatagagca cttcggccgc
    32581 actacgctgg ccttcattac caccggtgac catgccatct tcagacatcg cctttccgat
    32641 tttcacgaac gttttgacca gatcagggtg attacccagc ccggtggtgt tcagatattc
    32701 tttgagttca ggtgtcccga actggtcaag cgcacgctgt gcggcgctaa ggttagaaat
    32761 caacttgtcg ccaccgattt ctttgtcggc ttttacatcc gcagcccact gctcggttgt
    32821 tttctgccag gcttctgcct ggcgctgctg aacacctgcc agaatcttcg gataagcatc
    32881 aaccagcttt tgcgcttgct cgttggtcag gtttagttct cgcgccaccg gctcgaattc
    32941 cttcaacgct tctgtatcca gctctacgcc ttcggcagcc tgaaactcgt acttctcagg
    33001 cgcaccctct ggtttatcgc cgtccttttt ttcatcctgc ttatcgtttt caggcttttt
    33061 gtcatcagca ggtttatcgc catcagcaac aggttgtggc ttatcacctt cctgttgtga
    33121 tggatcacca actggagcag ggttatcacc tgcaggagct gacggttctg acgcagccgg
    33181 agctgctcca ccatcgactg gttgctcatt gcaaagacgg ctatacagca aacgctcaaa
    33241 taaattcatg atcactcctg ttcactggcc tctttggcca tcttcaaata ctgttcaggg
    33301 caatgcgcca taacgcgctg aaacagttcc agcgccagat tgcgttgccc ctcattaaat
    33361 gccattgcca tagcgtccat cggtgagata gcggaaaaca cacggccttt ctccagcacc
    33421 gaccagacaa cgcgacgccc ttgttcactg ctcatgacaa agcgaatgtc atcaatttca
    33481 cgctgcgcca tgtcacgttg cttacgggcg ttttcttctt tcagttgatc gtcttcgtaa
    33541 tctgtcattg tgattgccca ccctgaccac taactgcatt cgccatagct gacaaaacac
    33601 tcggatccga agttttagct tcgcttagcg tcttggcgcc ctgtgccgcc gccattccca
    33661 tcgccatcat ttgttgctgc tgttgctgct gtgcccgttg ctggcgagcc tgctcaacct
    33721 gttcctgcgg aacaatgacg gttggagaca ctccggacat atcagcgaat gcatcgatcg
    33781 cctgatcaac attgagtttg tcgagagctt ctggtttcgc ttgcgcaagt tgaccaatga
    33841 agttaaccgt ggacgccaga ctggacaggc cgatagactt ctgcgcctga gccatgacgg
    33901 aaatgtattc gaccttcagg ggcatgcctt ccatcgcgtc aggcggtggc ggcagcatgt
    33961 ttttacgcac catcatcgag aaagcgcggt caatgagagg attaagacat tcgtcgttca
    34021 gacgctccag aaccggcccc aacatcagaa gtttttcttc tttcatttcg atcaccgctt
    34081 caacaggcat cgagcgggta ttgatgttct gcaacatcat gaacagatcg acaaagtagg
    34141 cgctgttaat gatttgacgg gtgtcctgaa tgtctgccac caaatctgct gtactggggt
    34201 taaccagata agcaggcctg aaaccatcct gaccagtaat ctgatcgata tacgtgatgt
    34261 cgccaggaag aagggaggca cgctgattct tgagggaagt cggagcaacc atcggcggat
    34321 tggtggcttt atcaatcaac tgcgacttgc gcttctggag aagctgcaat gccttaacag
    34381 gtccaagcgc cagcataccc gggcatgatg atccataaac atcttcgccg ttaacttccc
    34441 agcgcggagc cataattgga aactcatcga atccggactc acgcaacaac ttgtcgttat
    34501 cgccaccaac ctcgtaataa accgatttga atggcttgtt cttgctatcc agcttcgatg
    34561 tatcgcggtc aatgttcggg taaaccgaat gcatcacttc aatccacttc tcgtaggtgc
    34621 cgctttccca catgcttttt acggattcgc tgacgttatt tagcccgaac tcctgaacaa
    34681 gctgacgaac agtcatagag aacttgcgaa aacaggtgtc cacactgcca cgaggtgagt
    34741 tagccaggta gtaactgcct atcgggaatg gcattgtgcg aatgatgtcc tcgtcatcct
    34801 ccagcactgc cattgcacca gtgctgtatg tgccgaggct tccgtataac tgcggcagag
    34861 actgatagag attcgactta ttgaacatat cgttcatgcg gttctgcacc gcctcaagcc
    34921 acaacttaac agggccataa tccatcattt caggatctgg cgtagccagg cgaaaccacg
    34981 gacgcgcggg gcttgtgatg cctgacatca tgccgctggc gagagtgcgc gccgccatag
    35041 tcccggtcga atcaataatg cgtgtattgc gccgatcgtt acggttggcc tcagaagtca
    35101 gaaagcggga accacgcggg ttgatgtaat cactcaactc gcgccagtgc ggctcgaacg
    35161 actgacgctc gctttcaagt tgtgcgaact gtttgttcaa tcgctcttta gttgtttccg
    35221 ccatttcaat gactccggtt actgaccaag cagcgtttta ccgctggtat tagcggttga
    35281 tgtgtcgccc tgagaaccgg taagcagcgt agaactacga ccagcagcag cgcgacggcg
    35341 acgtgtttct tcgtcgcggg catcaacaac ggcggcatcc tgctcctgtg gtgctgcctg
    35401 aacttctggt gttgcaggca ctgatggtga gctacccatg cacatatcaa tgactccgta
    35461 cgcaattaaa ttattaccaa tttaaccaca tatgatttat ttatcgtaga tagttgacat
    35521 ttaacgcaca aattattacc tttcaggtaa ccaaagagtt cattccggtt actaacctga
    35581 ctggattgtc gttaaattga acaggtggag tgagctttta ttttgagcag tacggcgtat
    35641 ggcacatgcg ccgatagcgg tctggatacg tttaaggggc accctccctt gctcgggcaa
    35701 acgaaccagg tagccggaat gtgcaagtcg agcggtttta ttccgcgcac ggggattcac
    35761 catcccggcg attcggtgtg acgcctcgga agagacgagg gtacaacgat gagagcattt
    35821 atggagccgc gacaaagtgt ggcgccttaa caggctaagt gctctcagcg ttgtggcatt
    35881 agctcagttg gacagagcaa ccgccttcta agcggttggt cgcaggttcg aatcctgcat
    35941 gccacgccag aatcacgcct aaggaccgtg atgccagaag ttccaggggc ttggcggtga
    36001 tggtttccct tgaaggacta tcaccgccct ttttacagca ggacgccatt gcgatgactt
    36061 catgctgtaa accagtacag ccacggaagg cataactcat tgcttccagt tcgcccggtt
    36121 cgccgggcat ttttttaagg tgagattatg aacgaccagc aaatcgaaaa agaaatcgtt
    36181 gagaaaggca aaacggcacc gcgtgtaaca cctgagaaaa ttgaaggcct catttgcagt
    36241 gagcattttt tcactgctgc gcagggtgat caccaggcta aagaagatga ccttatttat
    36301 aatccggagc cttatgtcga agccacccct gatgctctgc accttctcac tttctgcgta
    36361 ctggtgctga agaatggctt cactgtcacc ggagagagtg cctgtgcaag tccggaaaat
    36421 tttgatgcag aaattggtcg gaagattgcc cggcagaatg ctgtaaacaa aatctggatg
    36481 cttgaaggtt acttgctgaa gcagaagtta agcgagcaac aacacagtga catgtcacaa
    36541 acagccagcc gatgagctgg ctttgtttta tcctcatcag aggatatcaa cgacattatc
    36601 cccaccagcg gattaagcat acgggtcata atctgtgatg gccttgcctt gctggttctg
    36661 ctgccaggga agtcgcaggc gcttcgacac cgggaaagca aacgtcagca gcagcgcatc
    36721 gcctttaccc ggcgaacgcc caagtcgctc tttgatatct tccttcggtt cgataacgat
    36781 tttaccgtcc actcgaactt tgtactctgc cgccgacagg tcgtctgcag tttcctggtc
    36841 atccagcatg ccgcccagcc tcagccatgt cttacatgag ttgaacatct ccccacgctt
    36901 gttgagcatc tgcgggtcag tagacgcgcc accgaacgga acaagttgcc atgtacgacc
    36961 ccagccgtca ccgattgact tcagaccagt tccgtaaccg aagtcgatga acactgcgtc
    37021 agcctggtac tggtcttcaa agtcagcgat acgcttcgcc ataatcagat cgtcagtggt
    37081 cttgttgcca gtccacagca ccttactgtg cagcccctgc cgcaggtata tcacagcgtc
    37141 atcaacgcct gagtatgccg ggtcaacgcc gattatcacc ggagcatgtg caacctgcgc
    37201 agcggtgacc acccgtttca ttgcctcgtc agtaagtccg gtagggataa actgcaattc
    37261 agatgcatcc gggaatatgc cgcgcacacg gattttaacg aagtcgctgt cttccccgta
    37321 gtcatcaacc catttctgca actgctgttt gttggtgcct tccaccgtcc ggctgtcaat
    37381 ctgcgcagtt ttccagcggt gtttatattt gcggaaacat tcgcggaaac gtccggtatt
    37441 acgcgtcggg tttccgaacg ccacccagat aatctcagtg tcttcgtccg ttagcgcacc
    37501 ctcggcaact tcccacacca gatccgcaat gttcgacgct tcatcgaata ccacgatgat
    37561 gcgtttgcgc tcgttgtgta gtccggcgaa tgcctcagtg ttgtgctcag accagggtat
    37621 tgcgtcagct cgccaccgct tgtcgtgtcc aggatcattg ctgtacatcg cggtagcggt
    37681 acaggtaaac cagtctttcg tgatagcaag gttcgaccac ttgataattt ccggccaggt
    37741 cttcgttcgt agctggttgt cggtgttggc ggtcaccaca accttacaat cctcgcaagt
    37801 ggacatgccc cagttgatca gcattgagat gaatgcggat ttaccaatac cgtgacccga
    37861 agcgcgtgcc agcataagcg gctgatagcg cgtctctgga ttctgcaggt gatcacgtat
    37921 ctctcggaac gcatcagcct gccactgacg tggaccggtg gcatgtgcca gttcagtccc
    37981 atcttccccc cacgggaacg catagagggc atagccaagc ggatcgtgag tgaaccctgc
    38041 aatatcctcg attaactgct cttcaggaga taacgctgta tctgtcactg attaccatcc
    38101 tgacgttctt tgagtcgctt cctggctgct gctatgcgat cagcaattgt cacattcaca
    38161 ttaacatcca gacgttcttt gaatgcgttg acatcaacat gcttaccaat cagctcaagg
    38221 ttcttcacct tgtcaggcca tttcaccttc ttcaggatat gctcgacatc ctcaacagag
    38281 agatccgcct cgccattctc tttttgcagg gaagcctggg ttgtcttgat ggtagcgata
    38341 tccatagcac tgagagaggt acgccagacc ttcggccatt cagcgatcgg cttcatcccg
    38401 ccgtcatcgt tcagtatatc cagcacgtcc atctggtcga tctccaccag gcgcatgaga
    38461 acgtaatcag cactgacgcg cattcgtttg ttgcgctcct ccatcaactc ggcaatccgt
    38521 ttttgaatgc gttcatcgcg catcatgaca cttgctttaa ctgccgctgt atttggggag
    38581 aatcctgcgt taatcgctgc ctgagtctgg ttttcaggcg ttttgatgta tgactggcaa
    38641 taagcctcct gcattgctgt tagtggctta aattgcgttg atttacgttt ataggtttta
    38701 ggttcagcag gcatcataac caccgtggta atagttaccg ttgtggtaat agtaccatgc
    38761 aaaataaagc cgccatagtt ggcggcagta ttcaaagtcc atcaaattca tcgtaaaaac
    38821 tctcgtcaag ataccattcc catttaccgc gaatgaaaat tacatcctcg ccgcaagggt
    38881 gctgactgtc gataactata tccctcctgg cgcaaccata cttattcatg agaaatttaa
    38941 cctctttcgg aaaatttgct gagttatctc tcatatcttc aaggtcgtag cgtatttttg
    39001 gcataacacc ttcgtgacat gtcacactat taatttcgtt tcatgccagc ctttggtcac
    39061 ccagcattgc gagtcaccat tacacgggca tgaattaact ggaactctct cgccgcactt
    39121 accgcaacgt tttctgctga tcgattttat acgcccgcgc acgcgtgcat catcctggcg
    39181 gatcagtaac gctatatact caccaaattc gtaaggcgca cgcccggggc gacgcgtggc
    39241 acagttacgc tccagcattt caatttcctg agcatcaagc acaatttcca gcttacgcac
    39301 accagatgca gcttgtctgg ctctctgagc ggctttgcgc tctgctgctg atttagccat
    39361 caatatttac ctttatcgcg aacacattta ccggtttatc tcctttgcat agcacgtaat
    39421 tttttcagat ggttctcctg ttctgtttca gccaggatct ggtgatattc tctgtgatca
    39481 atgtgttcga ataaattatt gaattttctg atgcacactc ttccaggata gccatccatc
    39541 ctcttgaaga atactgagtg atcagtacta cgaatgattt ttactggata gccagcgcta
    39601 tcggtgtata tctgaccacg ttgaatcaga gagaacattc gtttatcccc agataaaaat
    39661 atagcaatac caattacata aaatacttca ggccaagcat catttcaccc ctgcggcggt
    39721 tctggtagag gcatccagaa caaggcgttc cctaaccacg ataaagtgcc gtcgctcaac
    39781 tccacgtatt ccccttgtac ctgtcctgcc atatactcgc cgtgctttga ataaattaaa
    39841 atccaatcat cttgagcggg cattcgctca ctacagctta tccaaccatc cggagtcacc
    39901 ggagttggtc catcgaattc gggcatgtca ggaccttttc tgatagcttt agccagctcc
    39961 agcgggtcat cgtaaagcca gtcgccagtt tgtgggtgat ttgcttctgc aagctgcgca
    40021 gcccattcaa gaccatcttt ttgaccttgg agataatcaa gtggcaactc ttcatgatta
    40081 cttgcaggtt cggcactatc agcttcgcgc cgcttctgta gctctgctgc cattgctctc
    40141 acgacttcaa ctggtgccct tgcagcaaac tctatgttgg tgatcagctc attaagatat
    40201 tgctcgcctg gatactgttt cttattggta atagtgatca tgccgcgttt ccttctttct
    40261 tattaacaat tacaccgtca tatatttcat taaggtgccc tctcaactcc atgcgcctta
    40321 atgcagataa catgtaatcg cattcaacct gcttattccc aataaaaggt ttatcttcag
    40381 ggttacccca acagcaattc cccttgggcc atccatgtac tttccgtact cttccgttaa
    40441 caacgtgaag taatccccag ccgggaggta aatcctcaac tgaaataatt cccggctcac
    40501 taataaagaa tcgccagtcg cccatgccaa gtgagggatt tttacggaaa cgcttttttc
    40561 tatctgccaa caagtcagca cgagaacact tcgcctctat caggcatgat gctgaatttc
    40621 tgaatcccat agcatctggc tgttctccgg tactggttac agctataaag cggtcatgaa
    40681 aacaaacctt gaacccgttg cgcttaagga acttgtacgc aatctgacag agttcgcagt
    40741 gtgttaacgc catatcactc tcctttgatg cgaatgccag tagcgcggat tgcattgatg
    40801 acttcagaaa ctttgtatgc cattaccgtt tggtaatcat cgtgaaaatc tgttcgatga
    40861 agcatgctgc tacgttccgg gagcagtatt tcccgcgctt ccagttctgc aatgcgcttt
    40921 tttgctgctt ccagttcatc cagtaattcc agcacggtag ccggattagc cttggcaaca
    40981 aaatcccgga ctggcttaca atcaatctcc gcaatgggtt gatacgatgt gtagccatgc
    41041 tgtcttgtat agctaccgtg acgaataacg aaaaaatcac catttatttt tttagcctgc
    41101 cacttatctt caccggcttt ctctgccttt tcacgcagtg cctgatagtc aatcttgttc
    41161 actcttcatc ctccaagtcg gcaacggcgt ccatcacatc agaaccgcga ataacctcaa
    41221 aagcacggca ggccatttga aataccagtt gctcttgcgg gtgaggagac tcccaatatt
    41281 tgaagcctgg gcgatgcgtg taccccatca ttgaataaaa atcaccagca agcttaatcg
    41341 cggcatcgac aagctctctg ttagtcattc tttttccgct cactggttgc ctcctttgcg
    41401 aagctgggcg gctaactcat cacatatgtg cgtcaaagaa caaagtttga ttgatggatg
    41461 ttcgcgcatc atctctaccc cctgcgcccg cacttcagac aggaaagcat cggtggctgg
    41521 catatttcct gttgccttca ttgcctccaa aataaccaga acgccatctc gcccaatctc
    41581 ctcgcagata acctcggtgc tgtcgccaac aacatcgcaa aatgcctgaa ctgctttacg
    41641 agccagcgca ttctccgcag ccagcgcatt agcacgcacc agttgcactt ccagctgcgt
    41701 tgccaaatcg ctgatcagct ttgccacact gcgcatatca acggcaccac attctgcttt
    41761 cagttccgaa gccatctcat gcccggcgga aactaaccct ttgatattac tttccatctt
    41821 taccctcgct tatccacata acttattgat tacattgata actaaaaaga tcgtcgattc
    41881 atgccgatct atttttcatc agtgattcat aaaacttttg ccacttatgc cgaccgaaat
    41941 tagccttcga gttacagctc gaacaaaggc aaataaggtt ctcctgacga caatcttgct
    42001 tgtcgtaatt gatgtgatga gttgttagcc ttttgtctgt tccatcacaa cctgggttct
    42061 gacaagtaaa accatctcgc tcaataaccc tcttgctcgt ttctcggaaa tcccacggat
    42121 acggcaatct cgataatcca ccagaccagt ttggatttcc ttcccccttc atcagagaag
    42181 aacgcattat gttggaacac tgtttcgagc agcatttatg acgcttctca tgactcaaga
    42241 aaacggagaa cgaagatccg catacgcagc atatttttaa tactcgcttt agttcccgat
    42301 ttaccgtctt gcctcgctgt gaaattccta cacactgaag tgagcagaac cttgaagatg
    42361 agttggctcg cttaacctga tattgcctgc cacatacgga gcaaaccttt tcgattttcc
    42421 cacccttcca attcgggttt ttatcaccgg atacaatcaa tcccgcagca ttgggcttct
    42481 cgctcatagt tcctcaacct cccatccacc accgagcttt ttaggttttg gataagcaac
    42541 ctgaaagaca aacggatagc tgtctgccgc aaccttcatc ttgactctcg catcgtcagt
    42601 aaagactgac ttacttccct taacgtccac catcaccaac tgcccgtcag ccaacatcac
    42661 ggcaaaatct acagtcagga agcagttgtc agctaaccgt agcttgatac cctcgaatcg
    42721 ataccaggcg atttcccctg cacgtttacg aagctcaagg tgctggcaat acgcagattc
    42781 tgttttgttc atctggcctg ttttgagtcg accaagagcc tgtatctgtt ttctcatgat
    42841 ttacccctga ggtaattaaa aaccacataa gacacgaaat caatagattt tagaatattt
    42901 tattacctaa caggtaattg tcgaggcgta aaaaaatgcg ctatcgcgct ggtattactt
    42961 gataaatcct gccgcctttc cccgcctgta ttcctccatc agccactgcg ccggtgccat
    43021 tccccccagg gtagcggcgt taggcataca cccgaaactt cgccctggtg gatggtaaac
    43081 gtctctccct gtgtccggag gcgtactcat gggttctggc tttgcctgta tgctgatcac
    43141 cggatcgggt atctgctgtc cggaagccac ctttttcgcc caatcatcaa gcagcctgcg
    43201 cgcgtgtttc tcaacctcaa tctcgctaag ctggcgctga tacattgcac ggcgggtatc
    43261 acatacgacc cagtacataa ccggatgccg ccacgggaat ctttcgggac caccaggata
    43321 taaacttttt tccttgctgt accggtgaaa ctccgccatc acatcgtcaa tggtgacgcc
    43381 aagaaccatc ttgctgtctt tacaccactt gataaattgc cctggcgacg gccagaacgg
    43441 agattcactg gcgcgggcgt ggcgcatacc agcagaaacc tgttcacggg ttcggatccc
    43501 cccttcggca aacgcagcaa tccactgctg ttttgcagca acttcctgct ctggcgtctt
    43561 caggttggtt accactgccg ccggaaacag ttgtttcagc tgtttaaaaa gggcatcaac
    43621 aagcctctct gctgacatgt tcaccacatt gtcattgttg acgtactgat gctcataacc
    43681 tgacatgcga gaaagggctt ctccgtcacg gttttgtatc gcggtaaaaa cgttgttcac
    43741 aagaaatcct cccatgcttc agggctgttc cagtgcggaa cgttgttatc aggtaatgtt
    43801 gattgcttct gtctgctaat ctgcagccgc cttgccagct tctgctccca ctgtgcctga
    43861 tggtatgcct taccctcagc catccagtaa attctgaact ctgcaagttc ctgtgccgtt
    43921 ggcagactgt ccaggtagat cccctgcaat gagcttttcc gaagaaagtc atctgatggc
    43981 tgccattgtt catgcatgac aaatttgcct aattgccctg gcccaccagg aggaacaaag
    44041 ttattcatca cggcgttgtt tgctccgggg tcatgaggca cagaatcccc gctttttgtc
    44101 ctgctctccc tctcttggtt aaatgactgg ttatatgact ggttctggat cccgtttttg
    44161 ggatcattca acatcccgtt tttgggatca ttcaacatcc cgtttttggg atcattcaac
    44221 atcccgtttt tgggtatatt aagagagaaa acccgcactc tttttgtcgc tccctttctc
    44281 tctccggtat ctgaaataat ccccattttc atgagcgata taagcccggc ctgcacggtt
    44341 tttttattca ggcaagtgtc tttaacgagg cgttctatgc tggggtagca gaggttatat
    44401 tcatcggctc tgtcagccat cgagagcagt atgagcttta atgatgagct acctggatct
    44461 gtctcccaag cccaatctgt tgcatgtctg ctcatgatta atctccgcta tcagcttgaa
    44521 tgttgtgggg aggaattaat catgatctgc ttaatctctg ccctgatgcg acggtttgac
    44581 tccatggtgc actcaacaca gtgtccgttg taaacccagc gttcactgtc atgtccgtgc
    44641 ttacatggtt ttccggtgta gtagcgttta agtccgcgct ttgcggcatc aatacgtgta
    44701 atgatttcca tggtaagccc tgttattagt attgggatta cggttatttt gtgctgacac
    44761 aaaaaaaaga tcaaccagat ttggtttttt attacctttg aggtacgaat agatatgaaa
    44821 agaccgccgg atggcggtct acagagggtt gttgccagat atcatgagta gaagaagtat
    44881 gccagttccg cttttgagcg cagccattgt cttgttttac atgctttaaa aagcccattc
    44941 atcaatacct tacctggcat tttgcgctta cctgttaagt gagtctggat atagtgactc
    45001 gtcgttccgg cttcctgtgc gaaggcttca cgctcatccg gagtaagtgc aagccagtgc
    45061 tttttgaaat cgaaatgtcc gttatcgctc atagctattg cctgatattt atttcagata
    45121 ataaatattc acccataagg taacaaaaat caaggatagt tacctatggg gtgcatttac
    45181 ctgttgggta atattgcttt aaattgaatc atctactgat tcatatatga ggcgattttc
    45241 cagaaaatga aaagtatcca ggacgtccgc aggcaaaatc tcaacgactt gatcgaccgt
    45301 gaattcaatg gtgttcagac gcggatggca gaaaaacttg gaactcaggc aaatctggta
    45361 aaccgctggg ctcttggcaa gaaggttatc ggcgaccagg ttgcgcgaaa aattgaagct
    45421 gccgccaata aaccccgtaa ctggcttgat atcgatcgct cgctttctca ggaaggtttt
    45481 cagcctgtcg gcccaagcga cattggtcag ctggcagctc acaacctgga acgctggatg
    45541 agtgaaagcc gcgacctttc aactcaggga aaacttcacc gcgcatccgg cgtcgcccag
    45601 gtgacaatca gccgcctgtt aaacaatgag gtcagcgttt ccatttccac cctggagaat
    45661 gttgcatccg cattcgggcg tcacggatat gaactactga ttcacccgca cgaccctgcg
    45721 actatcaact atgaccgctc acgctacgca ttgttacccg aaaccgagaa agcaaagatc
    45781 gaaagttaca ttgaatttgt catcaaccag aacgaaaaaa acaaacaata aaaccatatt
    45841 tttcagtaag taagccgcct tatggcggct tttttattgc ctattcgatt acctaacggg
    45901 taattttttt aactcatatc tattgacatc aaaccatata cgcataatta ttacctcaac
    45961 ggtaacagac cgaggtaaca agttatgcag tggaaaatca tcaacggttg gtactgcgtt
    46021 actgcatgcg gattcatgag ctggaagttc cgcaccttac aggaaggcat taagtgggct
    46081 ttcgtcagca aagaagctcg cgatgtggcc aacgataacg agatatggga gggctgataa
    46141 tgaacgttaa tcagcagaaa aatcttcaaa aaatcatgct ggcattcgac aaggactacc
    46201 gtctgtcaga acagctatat gaccgacaag ttgaactgat tgagagtatc cggcttcatc
    46261 aactggcatc aactttcgac gttgtaacag ttaaaggcgt tcgccaggaa gtactggagg
    46321 ccgctaaaga cagccctgag ttcgaagaac taatggatgc ctaccggcgc gaggcaatgg
    46381 caattatcgc ccgctgggat ctggctgatc agcttgatgg gcagagggac gcggcatgaa
    46441 accgggaatt tatttcgaca tcagcaacga agactaccac gccggtgacg gcgtgagtaa
    46501 gtcgcaactg gacatggttg ccaagaatcc ggcgcttctt aaatgggttc aggcagcacc
    46561 agaagacgaa gagaaaaagt ctgcactgga tatgggaacc gcattgcact gtctgcttct
    46621 ggagcctgga gagttcgaca aacgcttcat tgtttcaccg aaattcgatc gtcggacgaa
    46681 acaaggtaaa gctgacgaag aggaatttct tcgtgatgtg gcggatatgg ggattacggt
    46741 acttgatgcc gagcagtggc ggaaactgga gctgatgcgt gatagcgcaa tggctcaccc
    46801 ggcggcacgc tggatgctgg aagcacctgg ttactgcgaa gcatcaatgt actggaacga
    46861 tgaagagacg ggggagttgt gccgaattcg tccagacaaa tggctgaacg agcacaacgt
    46921 gatcgtcgac gtgaaaaagg ttgcagatat ggaccgtttt gcacgccaca tcgaggaatt
    46981 ccgctaccac gtgcaggacg caatgtaccg cgaaggcgca atgagggtta ctggtcagcc
    47041 gcatggtttt ttctttcttg ccgtgagcga aagcattgat tgtggtcggt atccggtacg
    47101 cgtgttcgag ctggatgcgc aggatgtcga tgccgggcac gctctgttcc gccgggatct
    47161 gaatacctat cacgaatgcc gcatcaatga tgaatggggc ggtgtggaaa tcattaaacg
    47221 ccctgagtgg gcacgcaaac aggatatgta catatgagca acgacatcgc aaacatcaac
    47281 gcaccagtag acacagcaat cgctggaact gctgcaacta ttttcagccc agacggcttg
    47341 aaccaactga tgaaattcgc cgaggtaatg gcgcaaagcc gcgtaacggt accggcgcac
    47401 ctcgccggga aaccagctga ttgcatggcc gtggcaatgc aggctgcgca gtggggaatg
    47461 aacccgtttg ccgtggctca gaaaacccat gttgtgaacg gcacgctagg ttatgaagcc
    47521 caattagtaa acgcagttat ctcaacgatg tcgccaacaa aagatcgcat caactacgag
    47581 tggttcgggc cgtgggaacg cgtgatcggt aagtttgttg agaaaacatc caaaaacggc
    47641 aatccatata tcgcaccagg ctggactcta aaagacgaag aaggctgcgg tgttcgcgta
    47701 tgggcaacca tgaagggcga ggatcaacct cgagtgcttg agttaatgct gtctcaagca
    47761 caggtaagaa actccacact ttgggccagt gatccgaaac aacaactcgc ataccttgcg
    47821 acaaaacgct ggtctcgcct gcactgtcct gacgtaatca tgggcgtcta caccccagac
    47881 gaattacagg aaacggcacc gcgcgttgag cgagacatta ctccgcaaac gaccactgct
    47941 gcgggaatga acagtctgat caacgctaaa ccagcgaaaa agcctgatga gcaaacgcgt
    48001 aaatcggaca gccgtgatcc agaagaaatg ctgatggcct ttaccagcgc agcgatgaat
    48061 tacagcactg tctccgaact ggataaggct tacaaataca ttgcacaaaa actttcagat
    48121 gatgacgaac tgctggcaaa agcaaccgac gtttacagcg ttcgtcggga agaattaaac
    48181 gaaacatcta tgtaaccacc accgcggcgc cacgtgcgcc gcactgcaac caagagaggt
    48241 attcatgaaa ggtgcattag gtaagaaaga actcctggcg gtggtgccac tgtcatggag
    48301 cactatcgac cgtatggagc gcgcagggga atttcctaaa cgctggtata tcaccgataa
    48361 acgctgcgca tggaaccgtg atgaagttga gcgttggctt gatgaacgtc aggcagcaag
    48421 cccggcagag ttccagggta aaaagcctcc tgttcagcaa cgtgtatatc gtcccgtgag
    48481 caacgctgca tgagtgcgct gctaaggcac tggagcaaat ggtcaggatg gtacttattc
    48541 ctggcctctg tttcagcatg gctttatctg ctggcattaa ttttcagaga gggttggatt
    48601 aagtgagaaa gttaagccga cttgaaaaat atcacatgaa taaggtttca atgcgcagtc
    48661 cgtcaaagat tgtcgccgtt actcctgcgg cgatagagat cgaaaaacgc gcgattgaaa
    48721 gagagaaaaa agggcaattc cgcattgccg ctcacctttg gcttcagtgt atggatgttg
    48781 cttctggtga tgttgaacgt gcaaggatcg cggttcgcag ggaccaatgt atcacaaaag
    48841 gtaacggcct tcgccgtggc gactatagcg gcataggatg ttgtggggtg gtttatgact
    48901 aagaaataca cactaatcta tgcagatcca ccctgggtat accgggacaa agccgcagat
    48961 ggtaatcgcg gtgccggttt taaatatccg gttatgagtg tgctggatat ctgccgcctt
    49021 cctgtgtggg atttggccga tgaaaactgt ctgttggcca tgtggtgggt gccaacacaa
    49081 ccactcgaag cactaaaagt tgttgaagcc tggggattcc gtctgatgac gatgaagggc
    49141 ttcacgtgga taaaatgtgg tagtcgacaa ccagataaac tggttatggg tatgggacac
    49201 atgactcgcg ccaatagtga agattgcctg tttgcggtaa agggaaaact acctacgcgc
    49261 attaatgcag ggatcgttca gtcatttacc gcaccgcggc ttgagcattc aagaaagcca
    49321 gatatcgttc gtgaaaaact tgtgcaatta ttaggcgatg tttctcgcat tgaactgttc
    49381 gcccgccaga cgtctcatgg cttcgatgtt tggggtaatc agtgcgaaga cccggcagtg
    49441 caactacacc ctggatacgc gttggatatc ggcggattaa caaatgcatt cagcaatgct
    49501 ccgctgtcac caacagacaa ccaggggcgg gagcgtgcag catgaaccta tatcaacgca
    49561 tcaatggcgc tgactggtgc aatatcttcg tcgtcggcga tctgcatggg tgctacacgc
    49621 tgctgatgaa cgaactcgac aaagtttcat tcgacccggc gcgcgatttg cttatttccg
    49681 ttggtgacct tgttgaccgc ggcgctgaaa acgtcgaatg cctggatttg attactatgc
    49741 cgtggttccg agctgttcgt ggcaaccatg agcagatgat gctggatgca ctggtcaacg
    49801 gcggaagttt cggacattgg atgtcaaacg gcggtggatg gtggcaccaa cttgattctg
    49861 agcaggatgt gcaactcaaa taccttctgc caaaggttac caacctcccg atgattatcg
    49921 aactggttac cggcaataag aaggtcgtca tctgccacgc agactacccg cacaacgaat
    49981 acgcattcga taagccagta ccggaagaaa tggtgatatg gaatcgtgag cgggttagcg
    50041 acgcgcagga cggtattgtc tcggagataa ccggtgccga tttgttcatc ttcggtcata
    50101 cgccagcaca tcacccactg gtgtatgcaa accaaatgta catcgacacc ggcgcagtgt
    50161 tctgcggaaa tctgacgctt accaaagtcc aggaaggata gaattattta ttactgtctt
    50221 ccatccactt ctcaaacttc gacggggaga acggaatcag atccgtatgc tccccgttaa
    50281 tccaggaatc aatcatatcg gcccactgct gcaacatgta ggcgcgctgt ctggcgtatt
    50341 ccgctttgtt atatacggcg cgcacacctt tctgctcgtg tgccagagcc ttttcaatcc
    50401 agtctgaagg ataaccagcc tcatgcaaca atgtactggc tgtacggcgc atatcatgta
    50461 cagtaaaatc ctgaatatgc tcaccatctt catttattat tttcaccgtt ctgtcgatca
    50521 gagagttcag cgcggcatta gataatggct tccggaaatt gtaacgacca ggaaccagat
    50581 attcacttcc accagcgcac atctgcaacc cgactaatat atcctgtgcc tgtttaggca
    50641 ggtaaataac gtgcgcccga cttcccttca tgcggtctga aggaattgtc catgtccatt
    50701 ttttaaaatc tatttcatcc cacgttgcat tggtgaattc tcccttacga accatggtga
    50761 taagcaccag ctttaaagcc attttcatag tgcccatagc accaatggca tccagcgtgc
    50821 ggaagaacag gccaatttct tctggtgtca gtgttcgctc tcgtggttta aatatggcga
    50881 tagacgaagg tttaatgtca gccgcaggat taaacaaacc atgaccacgg tcattggcgt
    50941 gacggtatac gctgctgatg atctccctgg cctgtactgc tgttgcccga ccaccgcgtt
    51001 cgacaatccg gtcacacaaa tcacgaacca ttgatgtggt aatttcagcc atcattttgt
    51061 tgccaagaac cggaagtatg tcacggtcga tcaccgcctg cttcattgcg cgggtactgt
    51121 cagccaggat gacgtgtttc atataactgt cggtatgtac cgcaaacgtc tcggcaccac
    51181 gaatcttttt aataccgtca cgtttagccg cagccggtga ctggcctgct ttaagcagct
    51241 tctttgcagc aatcagttct tctcgcgctt ctgccaggct gataccgtca cgcccatact
    51301 gcccgattac cagtgtttcg cggcgaccgt tgatacgata gtcatagcga aacgagaccg
    51361 tgcctgacgt aagcacagct acatacagcc cgtcacgatc ggagaccttg tacagtttgt
    51421 cctgcggctt gaggtttttt aattttgtat cggtaagcac aattcacccg tatagaaacc
    51481 attttcatga cggtatgaga gtataccttt aaggtaatac cgtcacctgt accgacgaaa
    51541 aatatggtgt agagtgaata gaaatgaata cataaaaaca aaaaccctct gtaaaaacag
    51601 agggttaaat tagtatctga ataggaatga gttgctatga gttagctgtt aatcattccc
    51661 actcaatagt tgctggtggc ttgccgctga tgtcatacac cacgcgggaa ataccattca
    51721 cttcattgat aatgcggttg gaaactcgac cgaggaaatc gtacggcaga tgtgcccagt
    51781 gtgcggtcat aaagtcgatg gtttcgacag cacgcagaga gacaacccag tcatacttac
    51841 gaccatcgcc cattacgcca acggaacgta ctggcaggaa gacggtgaac gcctggctga
    51901 ctttgtcgta caggtccgct ttacgcagtt cttcaatgaa gatggcgtca gcacggcgca
    51961 gcaggtcaca atactctttc ttcacttccc ccagaacacg aacgccaagg cctggtcccg
    52021 ggaacgggtg acggtacaac atgtcatacg gcaggcccag ctccagacca atcttacgca
    52081 cttcgtcttt gaacagctct ttcagcggtt caaccaggcc catcttcatc tctttcggca
    52141 gcccacccac gttgtggtga gatttgatga cgtgtgcttt accggttgca gaagcagcag
    52201 attcgataac gtcagggtag atggtgccct gcgccagcca cttcacgtct tccagtttca
    52261 gcgcttcttc atcgaatact tcaacgaaaa cgcgcccgat gattttacgt tttgcttccg
    52321 gatcgttttc gccagccagc gctgacaaga agcgatcttc tgccggtacg tgaacaatgt
    52381 tcagaccaaa gtgatcgcca aacatatcca gaacctgctc tgcttcgttg agacgcagca
    52441 ggccgttgtc gacgaatacg caagtcaggt ttttaccgat agcgcggtgc aacagcattg
    52501 cggttacgga ggaatccacg ccaccagaga ggccgaggat gactttatcg tcgcctacct
    52561 gctcgcggat gcgggctaca gcgtcgtcga taattttcgc tggcgtccac agggcttcac
    52621 actggcagat atcacgcaca aaacgctcca gcatgcgcat accctggcgg gtgtgagtca
    52681 cttccgggtg gaactgtacg ccatagaagc gtttttcttc gttggccatg atggcaaacg
    52741 ggcagctttc ggtgctggct acggtgacga agtcggacgg gatagcggta actttatcgc
    52801 cgtggctcat ccagacgtcc agcagcggtt taccatctgc ggtcagagca tcttcgatac
    52861 cgcgaaccag tgcgctgtcg tttacgactt caacctgcgc gtagccaaat tcacgttcat
    52921 tagaagcctc aacgtgaccg cccaactgca tcgccatggt ctgcatacca tagcaaacgc
    52981 cgaataccgg tacgcctgct tcaaagacat actgcggcgc acgcgggctg ttttcttcag
    53041 tagtactttc cgggccgccg gaaagaataa tgccgcttgg attgaagtca cgaatttgtg
    53101 cttctgtcac atcccacgcc cacagttcgc agtaaacccc cagttcacgc acgcggcgcg
    53161 caaccagttg agtatactgg gaaccgaagt ccagaatgag gatgcgatgc ttatgaatgt
    53221 tttccgtcat tgacgcttat tccgaggcaa gtgaaacaga taatataaat cgcccgacat
    53281 gaagtcgggc gaagagaatc aggagcccag acggtagttc ggggactctt tagtaatggt
    53341 cacgtcgtga acgtggcttt cctgaatacc cgcaccgctg atacgtacaa actccgcttt
    53401 agtacgcagt tcgtcgatag taccacagcc ggtcaggccc atacaggagc gcaggccgcc
    53461 catctgctgg tgaatgatct ctttcaggcg acctttatag gctacgcgac cttcgatacc
    53521 ttccggcacc agtttgtcgg cagcgttgtc gctctggaag taacggtcag aagaaccttt
    53581 ggacatcgcg cccagggaac ccataccacg gtaagatttg taagaacggc cctggtagag
    53641 ttcgatttca cccggagatt cttcagtacc tgccagcatg gaacctacca tcaccgcgct
    53701 tgcgccagcg gcgatagctt tagcgatatc gcctgagaaa cggataccgc cgtcagcgat
    53761 aaccggaatg ccggtacctt ccagggcttc tactgcatca gcaacggcgg tgatctgcgg
    53821 aacaccgaca ccagtcacga tacgcgtcgt acagatagaa ccagggccga tacccacttt
    53881 aacggcactg caaccggctt ctgccagcgc gcgggcacct gcagcagttg ccacgttgcc
    53941 gccgatgatt tgcaggtcag gatatttagc gcgagtttca cggatacgct gcagaacacc
    54001 ttcagagtga ccgtgagagg agtcgatcag cagaacgtca acgcctgcgg caaccagcgc
    54061 atcaacacgc tcttcgttac cagcgcccgc gccaaccgct gcacctacac gcagacggcc
    54121 ttgttcgtct ttacacgcgt tcggtttacg ttccgctttc tggaagtcct taacagtgat
    54181 catgccgatc aggtggaatt catcatcaac caccagcgct ttttcaacgc gtttttcgtg
    54241 catttttgcc agcaccactt cacgggcttc gccttcacgc acggttacca gacgctcttt
    54301 cggcgtcatg taaacgctaa ccggctggct caagtcggtc acaaaacgca cgtcacgacc
    54361 ggtgataatg ccgaccagtt cgttttcttc ggtaacaacc gggtagccag caaagccgtt
    54421 acgctcggtc agttctttca cttcacgcag cgtcgtagtt ggcagtacgg tctgcggatc
    54481 ggttaccacg ccagattcgt gttttttcac acggcgaact tcttctgcct ggcgttcaat
    54541 ggacatgttt ttgtggataa agccgatacc gccttcctga gccagagcaa tagccaggcg
    54601 cgcttccgtt acggtatcca ttgctgcgga aagcataggg atattcagac gaatagtttt
    54661 cgtcagctga gtgctgaggt cagcagtatt tggcagaacg gtagaatgag caggaacgag
    54721 gagaacgtcg tcaaacgtca gagcttcttt agcgatacgt agcatgggca atatctcgac
    54781 cagagtggtt aataaatatt gccgcggcat tatacagagc gtaaccgatt gcatctaccc
    54841 ctttttgcaa aaaatgcttg ctatccccgg agggcgggtt actatcgact gaataacctg
    54901 ctgatttaga atttgatctc gctcacatgt taccttctca atcccctgca atttttaccg
    54961 ttagccgcct gaatcaaacg gttcgtctgc tgcttgagca tgagatgggg caggtgtgga
    55021 tcagcggcga aatctctaat tttacacaac cagcctccgg tcactggtac tttacgctta
    55081 aagacgatac cgcgcaggtg cgctgtgcga tgttccgcaa cagcaaccgc cgggtcacct
    55141 tccacccaca gcacgggcaa caggttttag ttcgcgccaa tattacactc tacgagccgc
    55201 gcggcgatta tcaaattatc gtcgaaagta tgcagccggc cggtgaggga ttgctgcaac
    55261 agaagtacga acagcttaaa gcgaagttgc aggctgaagg tttgttcgat ctgcaataca
    55321 aaaaatcact cccctcccct gcgcattgcg ttggtgtgat cacctcaaaa accggtgcta
    55381 cactacatga tattttgcat gtgttaaaac gtcgcgatcc ttctctgccg gtgatcatct
    55441 accccaccgc cgtacagggg gatgatgcgc cggggcaaat cgttcgtgcc attgaactgg
    55501 cgaataagcg caacgagtgt gacgtgttga tcgttggccg tggcggcggt tcgctggaag
    55561 atttatggag ctttaacgac gaacgcgtgg cgcgggcgat ttttgccagt cgcattccga
    55621 tagtcagcgc cgtcgggcat gaaaccgatg tgacgattgc cgactttgtt gctgatctgc
    55681 gtgcgccaac gccgtcagcc gccgctgaag tggtgagccg aaatcagcaa gaattgctac
    55741 gtcaggtgca atctgcccgt caacggctgg aaatggcgat ggactattat ctcgccaatc
    55801 gcacgcggcg ctttacgcag atccatcacc gcttgcagca acagcatccg cagctccggc
    55861 tggcacgcca gcaaactatg ctcgaacgtc tgcaaaagcg gatgagcttt gcgctggaga
    55921 atcagcttaa acgcgcgggt cagcaacagc agcgattaac acggcaactc gtccaccaaa
    55981 atccgcagtc gcgtattcat cgcgcgcaaa cgcgcattca gcaactggaa tatcgtttag
    56041 cagaaaccct gcgcgcacag cttagcgcca cgcgcgaacg gtttggtaac gcggtaacac
    56101 acctcgaagc ggttagcccg ctgtcaacgc tggcgcgcgg ttatagcgtc accagcgccg
    56161 ccgatggcgc agtgttgaag caggtgaagc aggtgaaagt gggcgatacg ttgaccacgc
    56221 gactgggaga tggcgtggtc gtcagtgaag tgagtgcggt gacgaaaacc cgcaagccgc
    56281 gtaaaaaaac ctgatagccc gttgcgtatc aggctttcgg aacctcatat tgatagggtg
    56341 ggcaaggtta ttggaaacag gttgcaaacc ccggcgtttt cgcaggctga atgccacagt
    56401 tgagactgcc agagccttcc tcaacaccac aatagaacga tccagcctta tcagtagata
    56461 aatacgggaa gcttatcgat gacggccatc ccaatgtgct aaagccggag tgtaatgttt
    56521 gtaattcggc actgctcggc acgttattca tactaccgca ctgccgtgcg acatcccatt
    56581 tagtggaatc tataacatgt gccagcgccc aggtttcatt attcacattg ggcgttgctg
    56641 ctgcggtaac ccctgacggc aactccgatt ttaatagcgg gcgatgcagc atcttgccac
    56701 ttaccgtggc ggtatccgcc atatgacccc agaaatacgc cgtggcgaca ttaggactgg
    56761 tcggcacggt gaaaatcgtg tccagcgtcg ccgttattgt ggcgttatcc gtcagcgtca
    56821 ccgtcaacgg cgttttatat cctggcgtat tatcctgacc aacggtaaaa cttgctgtac
    56881 cgtctgctcc agtaactcca tcgattgtat tcccgctatc agccaacgtg actgccgcac
    56941 cggatgaggg ttgtacagtc aaatcgtcca ttgtatccac atcgccatac aacgtcgccc
    57001 cgctattacg cggcgtagcg tcaccacgtt tgaggataaa cgaaatattc ggcactggtt
    57061 tcccgacact gtctttcacg gtaacgacaa cgggaacggc gtcgcctttt ttcaccttcg
    57121 ccgcctgcgt actgctatcc agtgccgtcg atgtcaacgt gacgctggag acagtcgcac
    57181 gcgggttaac caggcaccct tgatacgcgg tattcaccgt cccccacgct gaaccattat
    57241 tcagaccgac tacctgcgga ttactgcctc ccagccagtt atccagcgcc caccatgtat
    57301 actgcgtaga ccaaccgatt tgtgtcgtca gcgtgttccc cggatagcga gcatagagcg
    57361 attctaaatc atcactcaat ggccgacgtg ccgcttcaca agggctgaga ttgctgtcag
    57421 ccctctgcgt tgcgttaaac acgggccaga cttcattgtt actattgacc ttgctaaccc
    57481 ctgatgtcga cggcagctct ttccacaatt taggtctttc aaagaccaca ccgttttctg
    57541 ccgttaccgt atccggcata tgaccccagt aggccgccat tgcggaatca gggctggtga
    57601 caacggtgaa gatcgcatca aggacagtgg tggtttccgt atcacgtgcc aggatggcgg
    57661 taaacggtgt tgccaggccg acagtatcag gctgttcaac attgaatatc gccgtaccat
    57721 cgctgccggt aaaaccaagc cattgcgtgc cgtgtgaggc gagagtgaat gttgccgaca
    57781 cgggtgccag ttccgtcaat accatcacat ttgctgccgt gtttacaatg gttcctgagc
    57841 ggctcatcgc attatcacgc ctgagcgtta tcgcttcgcc cgccagcggg ttgccatcac
    57901 gatctttgac cataaccaca attggcaatg ggttatcttt tttcactgac gcgctaggtc
    57961 ggccgccatt gctgagggtt ctggcgtcat ccagtgcgga tgacgtcaat gttacgctaa
    58021 cgcctgccgg atgcggctgc gccagacaga gcatcagtgc gttggttgca gaattcttcg
    58081 cgatagctcc tgttctcagg ctgacagtct gataagacca cgttgttgta cccagtatgg
    58141 ccatatcata agcccaccag ttacccgcat tcatcggtaa cccaaggtca gtcattattg
    58201 cgccgttcgg atgatcacta tacaaatcca acagttcctt actgcgcggt tgattctcga
    58261 gtgggcaatc tgtagatgtt aaattttgca agttgctcat atacgaccaa acttcgccgt
    58321 tagaactaat cgataagcct gagctggttt cggttttcag caggggtcgt ttgaaggtga
    58381 cgcccgccga actggtaaag gtgtccggca tatgccccca gaatttagca ctcggtgaat
    58441 ctgggctggt aatcaccgtg tagataacat ccagcgtggc gactttcgtt gtatcacgcg
    58501 ccagcgtcac ggttaacggc gtcgccaacc cggtagtaga gtactgccca acctcaaagg
    58561 tggctgtgcc atcactgccc gtcgttgcga gagtttttgc tccacttgct gtcaacacgc
    58621 tatccctact caccggaacc aatgccgtta cggtaagatc gtctgcactc gtgttaacgg
    58681 ttgctttcgc gcgatccagc gtcgtttcac gcgaaagggt aaagtcggca tatggcatcg
    58741 ggttcccggc gctatcacgc acggtcaccg tcaacggaat cagctcacct ttcttcgcta
    58801 cagcgctcgg tcgtccatca ttgctgagcg attttgctgc atcctgcgcc gttgaggtaa
    58861 gctctattgt gactgcttcc gtatgaggct ctaccaaaca catcactatc gccgtatagc
    58921 tggacgatgc ctgaatcaac tgaccatttc ccggaacaaa cgcctggtta ctccagctac
    58981 cgcccgctac cgccatcatg tcataatccc accagttccc tgcagcagtc ggcaagccga
    59041 gcaccgttgc cagttgacca ttgggataat cgacatacag cccctgcata tcagtcgtca
    59101 gcggttgata cgcctcatca cacccagcct tgctgacgtc cgctttctca gtcgcggtca
    59161 ggagcgacca gacttcatta ttggccgttt tcgccgtacc gccagagagt tcggctttga
    59221 ggaaaggccg tttgaaggtg acgccttcgc tgctggtaaa ggtttccgcc atatggcccc
    59281 aattggtcgc cagcggcgta tccgggctgg tggtgacggt aaagatcacc gacaaggtgt
    59341 ccgacgacac gccagtatcg tttaatagag cataaaagtc ggttcttaac ccagtggaag
    59401 catcctgtcg gagcgtcatc gtagtggttc catctggccc tgttacacca tacaggatgg
    59461 tcgttgcact ggtatccacc gtcgcacccg ccgcagtcgt gactgacact ttctgcgatg
    59521 acgtcacatt ctgacgattg atcgagttcg cgtgtttcag ggcaaacggc gtattgccga
    59581 ctaaattccc ctgcgcatct ttagtcgaaa tgcggatcga cacctcatcc cccttcttcg
    59641 ctttgacggc gctaagtgtg ctgtcaatgc tgacaaactg cccggggtct gaggcttcca
    59701 gcgtaatctg gctggcagtc atcaacggcg ttgtacggca ggtttgtaac gccagcacgg
    59761 tggatacgat ttgcgaaact gcgccagaat ttagttgcac cacattgtag taacggctcc
    59821 ctgtttgtgt attactcggg gtattggtga gataactcat atttaccggc catccctgta
    59881 ccgtattcat cgcattacct ctattggcgt catacaaaga cttcagacca tccagcgttg
    59941 gcatataatc tgtaccacac ccattcatgc tggtgtcagc cgactgagtc gaggtgaatc
    60001 ttgcccaact ttcaccgttc tcaaacgtgc tatatcgtgc atagttgttg gtaagctcgc
    60061 caaacagcaa cggtcgctta taaaccgaac catcggaggc cgtcaccgtt tcggccatat
    60121 gtccccaaaa attcgctttt ggcgaatccg ggctggtcac gacggtaaag accaccggta
    60181 gcatcgcctt gacgctgctg gacgtatcca gttttgccgt gagatcggtt cttaacccgg
    60241 tactgttatc ctgttttagg gtaaatgtcg ttgacccgtc ggcaccggtc acgccgtaaa
    60301 tggtttcact cgttgactgg aaattatttc gcgtatttcc ccacgcatcc gtcaccgtca
    60361 gcgcgcccac actcatcgtc gccgatgaat tagcccgact tacactgttg gctcgcgtca
    60421 ggataaatgc cgtattgccc acaaggttgc cttgcgcatc tttggtgatg acgcgcacca
    60481 cggattcttc gctttttttc gcttttacca cgttataggt ggtatccagc gtcaccggat
    60541 ctgccgcttc cagcaggatt tggctcaccg cggctatcgg cgcggtctgg caggtcagca
    60601 gctccagcgt cgttgatgac actgccgcac tcgtgccatt gctgagatct accgccttgt
    60661 agttacgctg ctccatgctg ccgttgtcgg aagtgttgga taaatagcgc gttgccaccg
    60721 gccagccctg cacggttttc atggtgttgc ccgcattatt agcaaacagt gacgtcagac
    60781 cggcctgagt cggaatatag ttggttccac agccgctgta cgtcgtggaa aaacttgcat
    60841 aattaatgtt aaacaacgcc cagttttcat tgtcttcaga cgttgatgtt cgcccagtct
    60901 gataggccag ttccttcaac aacagcgggc gcttaaatac cgtaccgtcc gcagcagtca
    60961 ccgtttccgg catatgtccc cacatttttg ccaggcggct atccgggctg gtcaccaccg
    61021 taaagattgt gtcgatgctg gattttttcg tcgcatcaga gtaaagcatt gccgtcagcg
    61081 ccgttttggt gccgtgagta tccgggcggg taatattgag aattttgctg ccgtcattgt
    61141 cggtcatggc ggtatacacc gttgcagtgt cgttcaacgt ggtttcatct gccagcccgc
    61201 cattgactac caccggcgca accagcgcat cgccgctgcc cgccacatgt ttttcgccgc
    61261 tacgggtata gccatcaccg cgattgaggg taaatggcat atccgctaac gcgttgccct
    61321 gtgcgtcttt taccgtcact ttaacctgta gcgtctcgcc ttttttcagc gttgccgcgc
    61381 tattcccggt attccattgc gctttatcaa ccacctccag cgtaatgctg ctggcaggtt
    61441 tgttcgccgt cttcaggcaa ctgacgtaaa ccggcgtatc gccgccaata gtttgtgcgc
    61501 catcgttcag cgctatcgtg aaaaagtgtg gagttttatc tgccggtgag ttgctccagt
    61561 aaggctgacg ctgtgttggc caaccgtgcg ccgtttgcac cgcgttacca ctgttggcgt
    61621 tatacagcgc acttagctgg gaacgacgtg gcaacatatt ggtgtcgcag ccacctttac
    61681 tggtactgga cgtattggcc tggctcacgc gcgcccagat ttcgttattt tcggtcaggg
    61741 ttccgtccgg gctggcgact tccgacgcca gtttaggccg ggtaaaggtt gatgaatcaa
    61801 cggtgatcgt ttcatccata tggccccaca tctgcgcgcc ggtaacgtcc gggctggttg
    61861 gggtagtaaa aataacgctg tagttaacgg tattcggcag gtaggaattt accggcgtta
    61921 cgctcagcac cgtttttagc ccgacgccct gtggttgctt aatctcgacc gtcgccacgc
    61981 cccgggcatc ggttattccc gcataaacct tcgatgactg tgatgtgccg tattgcgtgt
    62041 tatccatcgt gattgcacca ctgctcgggt catcaaaccc gctcacctgc cccgctcggt
    62101 tataccccat acctttggta atggtgaatg cagtaaaggg tacagggata ttattgagcg
    62161 agttaatcgt acgcacggtc atcacaatgg tgtcacccac tttggcttgc gcttgggtgc
    62221 caacagacac atcatgatcg gtgctgactt caacattcgc taccatctca ttacccgaac
    62281 aggagaggta attcggctta aagccggaat agctgtcgac gctcccgttc cccagatcca
    62341 ccgatgaatg cgtggcttgc tccaccgcgc ttaaatagcc ctgttgtgca gtgggccagc
    62401 catattcagt accaatcgcg ttaccgggat gggctgaaaa caggctttcc agtgagctct
    62461 ggcgcggtat atgaccgacg ccgcattccg cctgcatact ggtgttttga tcgtagagcg
    62521 cccagtcttc gttattttcc cgcactgttc ccaattcatg ctcggtttca tccgccagca
    62581 acgggcgttt atacaaactg ccggactcaa taatgccgcg catatggccc cacatccgcg
    62641 ctttgtcgct gtccgggctg gtgattacgg taaaaatcac atctttggca tctgtggcgt
    62701 taaaatcgct gcgcattctt gccgtgatat gggttttcac ccccgcgccg ccgggctggc
    62761 tcagggtgag cgaagcctgg ccgttggcgt cggtcatgcc ttcataggta tgtgcgtcga
    62821 cctggcgaaa attactgccg ccagcaatct gtaccggatg ggcttcccag gcagtgtcgg
    62881 tttgattctt acgattgacg ccatcatcca gatgtagcga gaagtagtaa tacgccagcg
    62941 gttgatcgtt gtttttcgtg tcggtgatgg ccagacgcat cgtcgcatcc tcgcccacct
    63001 tcgctttcat cgcctgcgcc gtgtcatcat agttttctgg cgtgaggacg attttcggct
    63061 cgacgtcagg cgcgggctta tccacgcagc tcacgaggaa cgtggtgctg tccggcttct
    63121 gcgtttcgcc acggttagag acatctgccg catggtgctg cccggtaagc cccgccagcg
    63181 atgaccagta ataatcgccc tgcatcggcc agccgagcac agtctgtacc gtggagggaa
    63241 tcaccgtcgc cagtgcgccg aagtggcgca tgcccggcag cacggtgcaa tggctatctg
    63301 cgccgctcca ggtaaaggtg gaccaggttt cattgtgatc gacgaccgtg gcattttcgt
    63361 tactgacttc cgccgccagt tttggtctac tgaacgtgta accatgggct tccaccgtct
    63421 ccgccatatg gccccacatc gtggcctgcg ccacgtccgg gctggtgagc acggtaaaga
    63481 tcaccgccgc ctcactggtt tgtgcaatgc cggaaatgcc gactaccagc ggcgttttaa
    63541 caccggggcc gttaggctgg gtcaccgtga tggttgccgt accgttagca tccgatgtgc
    63601 cacgatactc ggttaccgtc gtcgttaact cggtgctatc cagcaccacc ggcgcggtat
    63661 tatttaccgc gccctgacgg ttttgggcat ctttacgctt gataataaat ggaatattac
    63721 ccgcgacgtt accctgacaa tctttggtgg tgacggtcag cgtgatagtg ccgccaacgg
    63781 tggtttttgc cgcgccgagc gtttcgttat aaccactggc gctcaccgaa attaaatcgc
    63841 cctgcgcggg cgcgatattc agcgtcactt tctggtcagc cagcaccacc gtcccctcat
    63901 agggataacc ggtcgaggtc agcagataaa gcagtggaat ggtctgctgc gcatcaatct
    63961 gtggccaggc caccagcgaa cgcccggcca gaccttgcgc gcaaaagctg cggttggcga
    64021 tgggctgtgg attgagcggc gtatccggcg tggcggcatc cgcccacacc agactgacgg
    64081 tcggcggcgt ctggttttcc cagcgcagcg caggtggtgt agaaaactgg tcgccttcac
    64141 tgtcctgagg attagcaact atcaggttag cagcgtcatc gtcaacgcta aattcattcg
    64201 gtttagcaga aaacgccaca tcatgagatg cagcaggatc aagctgaacg cttccctgat
    64261 aaacgggtac gctggcgcta tcggcaatag gaactgtacc gttaaactcg cctgtagaac
    64321 caggatatgt ctgccattcc acctctgccc gtgcaaagtc agacagcata aaggctgcca
    64381 acatgcccag aagcacaatg atttttcctg gtttcagaca taccgacatg tagaaaactc
    64441 cagcatgata aacaaaacgt caacccgttt tgcttaacgc gtcgctaagc aaaacaggcg
    64501 gaaaacagca ttcccatacg ggaatgctgt tgtgcgcatt agtggtgttt gtaaatgata
    64561 gacagcgtat agccctgaac gccgtcgccg tttgccggga ttgcaaggcc ggtcttacca
    64621 ttacggtcac taccgttaag gctggttctt gcttgttcgt tagtttgcgg aataacaatg
    64681 tcattgttat cgaagctggc gttggcaata ccgcccgccg ccgcaagttg tttactgtta
    64741 ccgttaaaga cccacgcaaa gtcgtagtta gcggtaacgt ccacatccgt acccgcgtcg
    64801 tatttaccgt tctggttttc atccgagtac agtttggcca catacgtttt gttaagcgca
    64861 atggctgtat taccaccgat aaggttggta ctggtgtctt tctcgaagat ggcaactttc
    64921 aggttctggt taacaaccgg accaggatcg acattatccg tatcgctgcc gccaccgctg
    64981 gccgtagaaa tatccagcag agtcagcgaa gttccctgga agggattacc ggtctgagtg
    65041 ataggctgga tttcaacacc gatatagcgt ccacgatcgc catcggtgat tttataactg
    65101 gtttttcctg ccgccgcagt caactccgtt ttaccgccac ccgcattatc actgtagctg
    65161 taccatttga tggtcgccgt cgttttcgca tcaatgcctg cggaaccatc atcgatatcc
    65221 ccttcggtat cgccgatatc ccaacccagc gtgatggtat cccctgagta aaggcgttta
    65281 tcagactcgc tacctgcagg acggatacct ttactatcag atgtcacttt gatgtgatcc
    65341 gcatcttccg agttaatcgt agcattcccc ccttcgcgat agagccaggg tatggtcccc
    65401 tcgaattcag ctgtcgttcc actggcgacc caggcagcat cttccgccat agcgactggt
    65461 acggcacagt atccagccag catcagtgcc agcgcgactt ttgtcaggcc acgtttcata
    65521 tgaggtttca taaacactct ccttggttaa cattcagcgg tggcccgatc agccatggcg
    65581 ctgttcctat gtcttgctgt aattgacctg caaaccgtac ccttgcacac catcggttac
    65641 ctgggcacta aacttcgctg ccgcttcctt gttcgttgcc gggatctcga tatcgacgtt
    65701 agtggtattg gcttgcgcgc cagtattgcc atttacgcta tgccccgtga attcccattg
    65761 gtagtcatac tgtttcatct cttcgtcagt gagcttttca gatagctgga acacaccgtc
    65821 tttgttagcg tcgcgccaca acacaaagcg atatcggcta ttgaggggca acggttcttt
    65881 attgccgata agattcacgg atttagccgc accaacgcga tagataaagg cattcagccc
    65941 gccgatgtca gcccccagga acgttacgtc aacatagtta ctgtcatcat agggggcagc
    66001 tttcgccttc caacggaagg tgccaggcaa cgtactggag agcgtaacgg tccccttttc
    66061 tttatcttgt ttggcgataa agacacaggg agtctcggta gtgcaggggt tattcgtcag
    66121 cgtcactttt ttatcgttgg catcaaacag ctgcgggttg agattatcct gcggcaagac
    66181 attaccgttg cggtcagtgt tgtcgccaaa gctatcagta atatcgagat ccatcaccac
    66241 accatctaca ccatcagcct gtgcactggc ttcgtggctg tggttgttct cttccggcac
    66301 gttcgcgatg ttattaacaa tcagctcaat tttacggtcc tgctgaacgg tgatttccac
    66361 cacgcctgag ttctgtcggt tgcccttttc atctttcagc gccaggcgaa cccgccaggt
    66421 attgagtttt ccttgttcgg ctttgtcaga gctgtactgc cagacgggca gcaccaggtt
    66481 ccagtggtta ttgttgccct ctgtcagggt attctctttg ataaccggca tcaccagcgt
    66541 gcgggcggca ttgtttttcg cctgccatga cgcagcgaca attttgtagt ggtggttgac
    66601 aagcgcgtta atggtccatt tacatttttc cagcccgata gcttcttctg gcgtatcttt
    66661 aatcacgcac tcgggatgtt cattcatcgc atcagctttc agccacaaag tgacatcgag
    66721 gggatctttc tctttatatt ccagaacaat aaagttgtta cgttcaacaa agtcgtgacg
    66781 gctgcccatg agtgagtgag ccgcgctcac tttgtcagga tcaagctggt ctttgagcgg
    66841 gacgccaaac tggtagttaa gcgttgcgtt gaccgtggta tcggtgttat caccggttcc
    66901 tgctttgaag tccgttccta cagcaatgag cggaacaggc tggtatttca cgcctaacgt
    66961 gacagcgaag ggatctttct ctagattgtc ggtaccaaat agcgcaactt catccccgta
    67021 ataatgttcg aaaacgattt taccgccaag ctgcggataa gcgggaagcc aggcttcggc
    67081 acgaatatcc caaccgctcg cagggcgttc ttcataaaag tcgaaatctt cagagtcttt
    67141 ccagtcagaa agcggatgat aatagttacc agaaaatttt aaataatcag tccacgcttc
    67201 agcgcctata cctaaacggc gatgtccacg ggtaaaatca taatcataaa atatatttcc
    67261 acccaataac catttatcaa aattatgtct tacaccaagc cctatatttc cgatcgtacg
    67321 atcttctttt cgttgcgcag aaaattggct gaaataaaca gtggtttgat tatcgtacca
    67381 gggaacaaaa taatcgatgg aactgccatc cagatcgccg ccctgaccaa tggagaggtt
    67441 cgaacggacc ttaccgtagg gagagagtgt gtcttcaata taagattgtg cggttgaggt
    67501 gatttgactt tgcagatagc ttctggcctg agattccagc gcctcagggg tcaagttttc
    67561 aaacccttgc gtggcggagt tgatgacgta atcggctccg cgctctttca gcgatttacc
    67621 cttgttggtt tgttcatcct gttgtgctgc ctggctacct aaatcaggta acgattcgtt
    67681 ttgcttaaca tttatctctg gtgccgcgaa agcagcacca gagataaatg ttagcataat
    67741 acagcgtttc catcgcagca tgtgctttcc ctgtgacgat aaagtcaaaa ataattttta
    67801 atattatatt cctgattttt cagaaagaca tgttataaag aataaatata ttcttaatta
    67861 tttaaattag tgatttcgct cgctttcatt agttattcca ccataacaga ttgttttatc
    67921 atttgcacat taaatacaaa tgacaaaaca atacattcaa gtgatattaa gcaataacaa
    67981 attcaacgcg ttttttagat attaaaccgt gcccatgttg gcagaaataa tccacagcac
    68041 cacaagcttt taacacttgt aacggctgat gacactcagg gcaaagtgcc tggacggtaa
    68101 agtctttgtc gcaagttgca cagtgagcag tctcgccatt gcgttcgaga ggggttttgc
    68161 aggttggaca gttgagtgcc ataaatactc ctcgcgtgtt attcggtttc cctctccgtg
    68221 tggaaaggga aaccagataa gtgattactt acttttcttg atgtgcttca tcagacgctt
    68281 acgcttgcgc atctgagtcg gcgtcagggt attacgcttg ttcgcatacg ggttttcccc
    68341 ttctttgaac tgaatacgaa tcggcgatcc cattacgtcc agggatttgc ggaagtagtt
    68401 catcaggtaa cgcttgtagg aatcaggcag gtctttcacc tgattgccgt gaatcaccac
    68461 aatcggcggg ttataacccc cggcgtgggc gtatttcagc ttcacacgac gaccgcgtac
    68521 cagcggcggt tggtgatctt caacagccat cgtcatgatg cgcgtcagca tagaggtccc
    68581 cacacgacgg gtggagctgt catacgcttc acgtactgat tcaaacaagt ttccaacacc
    68641 actgccgtgc aaggcagaga taaagtgcac acgagcaaaa tcgataaagc ccagacggaa
    68701 gtccagcgtc tctttcacct gctctttcac ttcctggctc aggccgtccc acttgttcac
    68761 tacaatcaca agtgagcgcc cactattgag aataaagccc agcaaggaga gatcctgatc
    68821 ggaaatacct tcgcgcgcat caatcaccaa catcaccacg ttggcatctt caatggcctg
    68881 caacgttttg attaccgaga atttctctac cgcatcggtg attttgccgc gtttacgtac
    68941 gccagcggtg tcaatgagca catactcacg tccgtcgcgt tccattggaa tgtagatact
    69001 gtcacgcgtc gtgccaggca tgtcgtaaac aacaacgcgc tcttcaccaa gaatacggtt
    69061 agtgagtgta gacttaccta cgttcgggcg acccacaatc gccagtttga tcggcagact
    69121 ttgcgggtcg aagtcgtctt cctcttcttc ttcgccgttc tcttccgctt caaattgcgc
    69181 ccagtattcg gcgtcttcgt cgacttcttc ttgcggtgcg agatcttcca tccacggcag
    69241 cagcacgtgc tccagcagac ttaatacgcc acgaccgtga gacgcggcga tcgggtagat
    69301 ttcacctaaa ccaagcgcgt agaaatcaac cactgcctga tcgggatcca gaccgtcagt
    69361 tttgtttgcc accaggaagg tcggtttttc acgggagcgc agatgtttag caatcgcttc
    69421 atccgccggc atcaggcccg cgcgcgcatc caccataaac agtacgacgt ccgcttcttc
    69481 aatcgccagc agcgactgtt ccgccatgcg ggtttctaca ccgtcttctg tgccatcaat
    69541 cccgccggta tcaatgcaga taaactcacg gccttcaatt tccgcacgac cgtacttacg
    69601 gtcacgagtc agacccggga aatccgcaac cagcgcatct cgggtgcgag ttagacggtt
    69661 aaataacgtg gattttccta cgttagggcg cccgacaagc gcgaccacag gtaccatgtt
    69721 taaagcctca tttttataaa tcatcagaca acgcacgcta tattcgtgtc gttgttaaaa
    69781 acaggaaaac ggcccctgtc caggagccgt tttcaaagtg aacgacagag acgattaacg
    69841 tgtaatagag tacacggttc cgtcttttgc ctggatcagc agtttgccgt cagcagcaac
    69901 cggttcagtc tggaaaccgg aactatcaac tttttgctgg gcaacgaaac gaccatcttc
    69961 gacgttaatc cagtgcagat aaccttcact gtcgcctacc accaggttgc cattatacag
    70021 caccggagaa gtcagcaggc gatgcagcag atcgctttgt gtccacagcg taacgccgcc
    70081 atcaatggtc aacgccatca cccggtcatt ttgatcgacc agatagatgc gattgccgtc
    70141 gacgatgaaa tcattcaccg aacccagttc gcgtttccac ataatctgac cactgcgcag
    70201 atcaagcgcc gtcaggttac cattataggc cagcgcgaaa acaacgccgt taacaacgac
    70261 gggagtcgtg tcaacatcgc tcagacggtc aatttcggta gaaccggtcg cctgggaaat
    70321 acgctgctgc caaatcatct ggccctgttc catcagcact gcgctgacgc gaccattatc
    70381 gccacccacg acggccgcac caaaagccgt tgccggcgca gactcgccac gcaaagagag
    70441 cgaaggcata tcgaggttaa ctgtccattt gacagcgccg tcagcttcgt tcagcgcttg
    70501 taactgaccg ttactggtgt ggattaacac cagaccgtcg ctgaccaccg ggcgcgaaag
    70561 tgcttcaccc gcgactttag tttgccatgc cacagtacca tcgctggtat tcagcgcgta
    70621 aacctgcgcc ttttcggtgc caatgtagac atgcccacca gacacggtca cgccgccaga
    70681 aagtaatgca ggatctttag agaaccagcc atctttctcg gccaggttga cagaccagat
    70741 ttctttgccg tcatccgcat tcagcgcttt tactaaacca gcgcggtccg ctgcatagac
    70801 aacgttgtcc gccagtgccg gatgaagatt ggaatagaag ttgccaatgc cgctaccaac
    70861 ggaagtgctc cacacagtag tcggcgtaaa ctggttttca acggttggca atggggacat
    70921 ctttaccaca tcttcttcgc tgttaaacag cgaacagccg cttaaaaggg taacggaaag
    70981 cagtcctggc agcagtaatt tacgcaattg catcgggtcc ctctcagatg gacaaattat
    71041 taattttcat ctgcatcatt tcgctcagtg ccggggtaac atcgcttttc acgcctgctt
    71101 cccatgcact acgcgcacct tgcttatcac ctttgctcag caatgcttca ccacgcaggt
    71161 cggcaacaat ggcagcccac ccttcacctt tgatagcatc aagggttttt agcgcggcat
    71221 cagcctgctt gagctgtacc tgaacgcgag caagacgcag atttatcacg gctttgagat
    71281 tttcatcgct cgtgtctgcc agcccctgtt gtaactgggc ggcagctttc tctagttcat
    71341 ttttgtcaac aaattgctgc gcaagttcca aagaagccag cgcaccataa gtatttttat
    71401 tttcagcagc aaatttttcc gccgctggga tgctatccgg tttgccttcg ctcactgcgg
    71461 taaccgcatt ttgataggca agagaagcgg agcgtgcaga atcaacctga tggctattcc
    71521 agtagcgcca gccaatcagt gcgccaacgc ccaaaatcac cccaacagcc agtgctttgc
    71581 cattttcagc aaaaaagcgt ttaaccgctt caacctggtc gttttcgttc tcgtaaattt
    71641 ccacgctgtc cttctccttc cttaacccag taacgtgcgc aaatgcgcgg ctacgctatc
    71701 ctgcgcaact gcagtttgct caccagagcg caaatccttc actactgctg tgccgttagc
    71761 cacttcagac tcacccagca ccacagcaac gcgggcaccc catttatcag cacgggcaaa
    71821 ctgtttctta aagttgccgc cgccgtggtt ggtcatcagt ttcacacccg gtaattcatc
    71881 acgcagacgc tctgctaatg ccatagccgc agattgtgtg tcagcacctg aagccaccag
    71941 gtatatatcg acaacaggat cggctttaaa ttccggatta acggcctgaa ctaacaatac
    72001 aagacgttcg aggcccatcg caaaaccgac tgccggtgtt gcacgaccac ccagttgttc
    72061 caccagaccg tcataacgac cacctgcaca cacggtgccc tgggaaccga ggctgttagt
    72121 cacccactcg aaaacggtac ggttatagta atccagaccg cgcaccagac gctggtttac
    72181 agtgtaagcg atccccgcgc tctcaagcag tttgcacaga ccggcaaagt gctcacgaga
    72241 ttcctcgtcc agataatcgc ctaatgccgg agcgtcgttg agaagcacct gcacttccgg
    72301 attttttgaa tccagtacgc gcaacgggtt agtgtacatg cggcgtttgc agtcttcgtc
    72361 cagcttttct ttatgctgct caaggaatgc caccagcgca tcgcggtaat tcgcacgagc
    72421 ttccagcgaa ccgatagagt tcagctcaag agttacgtgc tcggaaatac ccagcgcgcg
    72481 ccaccagcgg gcagtgagca taatcagttc ggcgtcgata tccggacctt gcagaccgaa
    72541 aacttcgcag cccaactgat ggaactgacg ataacgccct ttctgcggac gctcgtgacg
    72601 gaacataggc ccgatatacc acagacgctg ttcctgattg tacagaagac catgctcgat
    72661 gccggcgcgt acacagcccg ccgtcccttc agggcgcaga gtcaggctgt cgccattgcg
    72721 atcctcaaag gtgtacatct ctttttcaac cacgtcggtg acttcaccaa tcgcacgttt
    72781 gaatagcggg gtctgctcta caatcggcaa gcggatttca ctgtaaccgt agctgccgag
    72841 cacgtttttc agtgtgcctt caatgcgctg ccagatggcc gtttcgccag gcaggtaatc
    72901 gttcatgccg cgaatggctt gaatgttttt tgccacgttt attctctttc tgaatataaa
    72961 aatgaaccct caacgcttcc ctcaatgttt cgggagccat gcgggttcaa tcatacacgg
    73021 gaagcgaggc gcttcccatc acgttattat ttttcaacct gctgaacgtc aattcgacgc
    73081 gcttcgtcca gctgactggc tttcgcacga atgcgcgctt ccagctgatc gatcatatcg
    73141 ttgttgtcca gacggtcttt gcgcacgcca tcttcataga ggccgctttt cttgttgccg
    73201 ccagtgacgc cgagtgtaga aaccagcgcc tcacctgggc cattcaccac gcagccgata
    73261 atcgaaacgt ccatcggagt gattatatct tccaggcgtt gctccagcgc gttaaccgta
    73321 ccgataacat caaattcctg acgcgaacag gtcgggcagg cgatgaagtt gatcccgcgc
    73381 gaacggatac gcagcgattt caaaatatcg aaaccgactt tgatctcttc gaccggatcg
    73441 gccgccagcg atacgcgcag cgtgtcgccg atgccttcag acagcagcag acctaaacca
    73501 atagcggatt ttactgcccc gctgcgcgca ccaccggctt cggtgatccc cagatgcagc
    73561 ggctgatcga tttgttttgc cagcaaacga taagactcaa cagcgaggaa gacgtcagac
    73621 gctttcacac tgactttgaa ctgatcgaag ttcaggcgat cgagatgatc aacatgacgc
    73681 atggcggatt ccagcaacgc ctgcggcgtc ggttcgccat acttttcttg cagatctttt
    73741 tccaacgatc cggcgttaac gccaatacgg atcggaatgt ttttatcgcg cgcacagtca
    73801 accaccatgc gaatacgctc ttcattaccg atattgccag ggttaatacg cagacaatcg
    73861 acgccgtatt ccgctacttt cagcgcaatg cgatagtcga agtggatgtc agccaccagc
    73921 ggcacgttaa cctgctgttt gatgagtttg aacgcttctg ccgcgtccat cgtcggtacg
    73981 gagacacgga cgatatcagc gccaacgcgt tccagcgctt tgatttgatt gaccgttgct
    74041 tcgacgtctg tcgtacgcgt attggtcatg gactgtacgg cgatgggagc accatcgcca
    74101 atcggcacat tcccaacgta aatacgtgtt gattttctac gttgaattgg agcctggtta
    74161 tgcatgaaaa atctcccgcg ttacccgtct gttactgcgc cggtgattgt tcggcattga
    74221 gggtcagacg cgcaacctgg ttagttctga taaaacgact cagatcgaca ggtttccctt
    74281 gatactggat ctgtactgcg gctggcgcac caattttcag tttgtacggt gcctggccgg
    74341 ttaagttcaa attaccgtct ttacgctgca taccgctaaa cagtttttta ccggtagcat
    74401 cggtgacttc cagccagcaa tcggaagtaa agttcatcac cagcgcattc gggtcaaccg
    74461 ccggcgtggt cacgccagcc tgatcggttg gcaacggcgc agcgccatct ggtgttgttg
    74521 ttgccgctgg tgccggagtc gcagcggtat caacatttgc ctgcgaaggt ggaacaaccg
    74581 cattctgttg cggatcaaca gctggtgctg gcgcagttac ggcaggtgtt tgcgtgttgg
    74641 ttgcggtggt atccacaggt gatgtcggcg tggtcgccat agcctgatct gtggttgtcg
    74701 acgtatctaa cggtacactc tggctttgat tattattcag ttccgcagaa gattgatcgg
    74761 ccatagtggt gatctcttcc tgctgagctt tgtggtcttg ccaccaccag gcaccgctca
    74821 gaccaataac cacaaacaac accagccagg tgaaggtcat cagccagccg tcacgttttt
    74881 tgcggcgttt accgagggaa aaactctgca tcggcgcaac ttttgcagcc cgtagtggag
    74941 cctgcttttc cagccctggc agcagttctt cttctggaat atgtaccaga cgcgcataag
    75001 agcggatata tccgcgcagg aatgttgaag caagatcggc gggtgcctta tcttcttcaa
    75061 tgtcgcgtac cgtggaaacc ttcaggcaaa gtcgctcggc aacggcctgt tgactaagtc
    75121 ctagttgttc gcgagcatta cgcaggcgag cgccggtagt aagtgcttca ttttggtcgt
    75181 gcgtggcttc agtattcatt cgctgcaggt acgtttaaat gagaattgag atgccggtga
    75241 accatcatgc tcacccacac cgcgaaacat ccgttaagtt aaccgttatc atacagtata
    75301 agaccgtctg tgtgctcgtg acaaagccca cattcgctaa ggctaactta ctgttgcatc
    75361 gttacatact gccttaaagt cagcaaaaac gcaccgttaa tattgaccag acaattgcaa
    75421 cttaatactt cattcataaa agattacgcc acggtacata aagtaaccgt ggcgtaatgg
    75481 ctatcagacc gctttaatgt cgatggcttc accctgcatc cgtttacgca gggtacgttt
    75541 cgtacggtcg ataacatcgc ccgccaactg accacaggca gcatcaatgt catcaccacg
    75601 agttttacgc acaatagtgg tgaaaccgta gctcatcagc acttttgaga aacggtcgat
    75661 acggctgttc gaactgcgtc catacggcgc gcccgggaac gggttccacg ggatcaggtt
    75721 gatcttacac ggcgtatctt tcagcagttc tgccagttgg tgcgcgtgtt cagtgccgtc
    75781 gttaacgtgg tcaagcatca cgtattcaat agtgactcgg ccctgattgg cgttggattt
    75841 ctccagataa cggcgcaccg ccgcaaggaa cgtttcgata ttgtactttt tgttgatcgg
    75901 cacaatttcg tcacgaattt cgtcgttcgg cgcgtgcagg gaaattgcca gcgcaacgtc
    75961 gatcatatcg ccgagtttat ccagcgccgg aaccacaccg gaagtggaaa gcgtgacgcg
    76021 acgttttgac aggccaaaac cgaaatcatc aagcatgatt tccatcgccg gaacgacgtt
    76081 gttcaggttg agcagcggct cgcccatacc catcatcact acgttagtga ttgggcgctg
    76141 accggtgact tttgctgcgc cgacaatttt cgccgcacgc cacacctggc cgataatttc
    76201 cgatacccgc aggttgcgat taaagccctg ctgggcggtg gaacagaatt tacactccag
    76261 cgcacacccc acctgcgaag agacgcagag cgtggcacgg tcgtcttccg ggatatacac
    76321 cgtttcaacg cgctgatcgc caacggcgat cgcccattta atggtgccgt cagatgaacg
    76381 ctgttcttca accacttccg gtgcacggat ttccgccacc tctttcagtt tgccgcgcaa
    76441 cactttattg atgtcggtca tctcatcaaa gttgtcgcag caatagtgat acatccactt
    76501 catcacctga tcggcgcgga agggtttttc acctaaatct ttaaaaaact cccgcatctg
    76561 ctgacggttg agatccagca ggttgatttt tccatctttc gtggtgacgt tttcaggtgt
    76621 gactaattgt tcagacatat gctattccgg cctcgttatt acacgttatg gcccctggag
    76681 ggttgaaaaa agaaacgccc cggtgagcgg ctgctcgtcc gggggcgctg cattgtacaa
    76741 attctggcgc acggatgcca cgtttgcacg cggcatttac gaaattatta acgggtgcgc
    76801 gggcacactt cgccttcgcc gaagaaataa gcgatttcgc gagcggcaga ttcgacggaa
    76861 tcagaaccgt gggtaccatt ttcggtcagg ctgtcagcgt aatcagcacg cagagtaccg
    76921 gccagtgcgt ttgccggatt ggtcgcgccc agcagatcgc ggtgacgctg aacagcattt
    76981 tcaccttcca gcacggaaac aacgatcggg ccagaagtca tgaattcaac cagaccatca
    77041 aagaacggtt ttccatcgtg ttcagcataa aagccacgag cctgttcaac ggtcaggtgc
    77101 agcattttgg tgccgacaat tttgaaccct gcagcttcaa agcgcgcaaa gatactacca
    77161 atcacgtttt ttgctactgc gttcggtttg atgatggaaa aagtacgttc aatagccatt
    77221 tttacctctg taaattgttc tgttgttgtc tgtaccagcg tacgagatgg cgcggattat
    77281 aatgagcaac agggccgttg actattgatg aaggtaacat ttttttaaaa taaacccagt
    77341 ttaagcaaca atcagggaca aaacagacta ttgcatgaca aatttcactg tcgctatttg
    77401 ccccacgtca tccatcacca gcaattgata atcgccttta tccgtcaaat gcagggtcac
    77461 gttgcgccca cgttcagtta acggttcgcc gttcagaaac caccagcgtt cacctgcccc
    77521 tccacttgat tgcaacggca aagtcgcttc cgctgcgccc ggtaaacgtt taataatcgc
    77581 gccatcgcgc acacctgtta gctgcagcgg gagttgtgca tcgtgaccgt atggcgggca
    77641 aattgtcgag gccggaggca agcgcacagc gcgacgttct gatgcgggca gccagggttc
    77701 cagcggtagc ggccagacat ttatcatttc ttgtcgcgcc tgagggcaat cagcggcaac
    77761 acgtttgccg ttttcatcca gccagatggg gaaacgaatg ccattaatgc cttcctgctc
    77821 cggcagtaat agagttggcg gctggctccc gtccagcagc caggttgcca ggcggcggcg
    77881 acagttaccg tcaccttccg gcaaagactg tccgcccggc cagcagataa cgccacgact
    77941 tacagagtca ggacgtgggt cttccggcaa attcacactg cgcgacagta agatattatt
    78001 aacctgattc aacagcggta cggcactggc aaagccaaac tgaccaacaa cgggcgtgcc
    78061 gtccggtctg ccagtccaga tcccaatgac atagcgagcg ttaaccccaa tcgcccaggc
    78121 atcacgatag ccatagctgg tgcccgtttt ccatgccagt ggggcgacgc gcggcaaggc
    78181 accatccggc aagggttgcg cttcatcagc cataatccgg cgaatgatcc acgcagcccc
    78241 cgacgacatt aaaggccgtt caagcagcgg atcgtcaggc tgtaagcgca atttgcctgc
    78301 cttgccgtgg cgagcaaacg cggtatacgc tgctgccata tcttccagtt ttgcgccagc
    78361 gccgccgaga atgagcgaaa gattcggcgc agcaccgttg ggcagataca acggcaatcc
    78421 aacattgcgt aactttgccg caaaccgttt cggtccatag gcttccagca cctgcacagc
    78481 aggtaagttc agcgatcgca ccagcgcctc actcatgctg atcgggccat gaaaaccgct
    78541 gtcaaagttg ccaggtcggt aatcaccggt gcgtcggggg acgtcttgca acagcgatgc
    78601 cgggtggatc acgccttcat ccagcgccag accataagca aacggtttga gcaccgatcc
    78661 tggcgatcgg atcgcattga ccatatcaac atgaccaaag cgtgaatcat cgttgagatc
    78721 aaccgatccc acccagccgc gaacacgcat atcggtatga tcaaccacga tcatcgccag
    78781 tgagctgcgc ggtggcaatc gtcctttcca gttttgcgcc agttcttcca gacgtcgttg
    78841 aagaccggca tccagcgtag taacgatttt gtcgcttttg cttttaccga gcatcatgcg
    78901 cgaaaacagc ggtgccagtt gcggcatttg tcggggtgcc agccagatgg gttcttccct
    78961 tgactctttt acccgctcac gggaccacac accttgcacg gccatccgtt cgagcacttt
    79021 attacgcgcg gcttcggcac gctccggcca acgatccggg cgaagacggc tgggcgcttg
    79081 cggcaacacc gccagcattg ccgcctcgga atagcttaaa ttcgcaggcg atttcccgag
    79141 ataagcccaa cttgccgcac caatcccctg caacgtaccg ccaaacgggg cacggttaag
    79201 atacaaggtc agaatttcac gtttagacag atgccattcc agttgcaacg cgcgccagag
    79261 ctgacgaatt ttgccgccaa acgttttggg gtgaggatca agcaggcgcg ccacctgcat
    79321 ggtgagcgtg ctgccgccgg aaatgacccg acccgacgtg agatcttgcc aggctgcacg
    79381 cgccaccgag aacggattca cccccggatg cttccagaac cagcgatctt cataattgat
    79441 cagtgcttca aggtaacgtg gagaaacatc ttcgattgtt accggataac gccagatgcc
    79501 gtcagcatcg gcgaaacgcc agagtggcgt accatcctgc gccaccacca cgcgtgcagg
    79561 attcacttct tgcaatggca gaggccagag tttatctgct gcccatgctg ccagaatgat
    79621 gataaaaggc gcggctgtca gcattatcca gcagccgcgt ttggttaaca ggcgaggcat
    79681 ttacggtctg actatcaaca gatcgtcagc cgcaccagtc gcccgccatt gaggaacata
    79741 cattgattcc accataggct gcggcacctg atacgttccc ggcgtcaccg cccgcgccag
    79801 atacaccagc gttaccggtt gatattcatc aacggcaacc gccgccacaa agcgatcgtc
    79861 acggaactct atgtgcttaa tgctcgcctg ctgcatctgg ttcagcaagt tctgcacttc
    79921 accaccactt tgctccaggc tggcgccgcc gttcgccaga ttctggtttt ccagttccag
    79981 ccccgcaggc aacagatcca cgactaacgc atccggtaca ctgttactgg ctttaacctg
    80041 caaccacacc agcaccagat cgccgctacg taacgagtcc agcgatttgc tcttaccgtc
    80101 agtacccaga atatgacgct caatttgcag cacattgctc gccggtaaag gtgcggattg
    80161 cggataaccg ctggcatcca cacgcagcca taacggctga tcgccactgt tggtcacctg
    80221 caaggtggca agttgatcgc tattcagatt gctggtttgc gctttctcgc ctgtcagcgg
    80281 ctcagcagag aaagtggttt gcgcctgcca tttgcccggt aaatcctgaa gagtacgggc
    80341 agccaggaac aacgcgttac tttcctgcgt cgatagccag cgttcaccga acgcctgctg
    80401 cgaaagtgtg ttcaacaggg agtactgctc atcgggtagc agtttgttct cttccagcaa
    80461 tgagagcatc aacgcgctgt cgcgcagtgg actaccgtaa tcacccagcc atatccgctc
    80521 atcactatta cgcggcgttt tcagcgccag cacaatcgct tcttcaccac gcgttgcatc
    80581 acccatgatt ttcagcgcaa cgccaagttg cagcagcggt aaaccagaag cggcatctgc
    80641 acgatgctcc cagatttcac gcagcgcacc cagtggtgct ttttgctgac gggccaacac
    80701 cagcgcagcg taagactgta cggcgaattt actggctttg agattatcag cgtacgggat
    80761 cgatatcatg cccggatctt gtaaatagcg cagcagacgc tcattacccc ggttaatggc
    80821 gtctgtcggt acgctgtaac cctgttcgcc tgcgcggacc aggaaatcca tcacgtaagc
    80881 cgtcagccag tactcttcgt caccgttttt atcccacagc gcaaagccgc cgttatcacg
    80941 ttgcatttgc agcaaacggg aaatgccgat atcgaccgat gcacggcgtt tctcatcact
    81001 gtcgcctttg atgcccaacg cctgcagttg ggctgcattg gtataaagtg acgggaacag
    81061 gccgctggcg gtttgctcga gacagccgta cggatacgct tttaactctt tgatataacg
    81121 tgcgatgttc agcggtggtt tgccgctcaa caataactgc ccttccagcg taacaggcga
    81181 gaagttttgc aatccatcag ccgggagcgc ccaggtttca ccaggctgta acgccgtacc
    81241 gtaattgacc gtttgtgccg ggaatgccgg acggacgccg attttccact gcttatgctg
    81301 atcggcaacg gtttcccccg gtaacgctaa cccgctaatg gtggcctgaa tgtcaccatc
    81361 gccataaccc gtcagagcac gcaccgggat aaacagcgta gtacgcaccc ctggcgctaa
    81421 ttcaacaggt gcgggggaat tactcaccag ttcaagcaag ccactggcgg tcagagcaac
    81481 attaagtttt tgcggtttat cggtaagatt agtgatatcc agcgtcaggc gcgaggtatc
    81541 gccactcgcc ataaagcgcg gcatgttaag ttcagcaatc accggtgcgg caacaatcac
    81601 tttgctttcg ttgcttccga agtcatctgc cgtccaggct tgcgccatga cgcgcaattc
    81661 accgttaaaa tcgccaattg gcagtgtaac cgagccttcg ccctgttcat tgagcgttac
    81721 cggcagcgcc tgctgcgcga caatattgac gtgattgacc ggcggtttac caccacgttt
    81781 cagctcatca ccatcaccac caaaacgcag agctgccaga cgcccctgac cttcaataac
    81841 ctgaccgtaa atatcgtaaa tgtctgcgcc atagcgtttc tgaccaaaga acgcctgcca
    81901 cggatctggc gtgacgtaat cagtaatatt cagcacaccg ctatcaacgg cagacaccag
    81961 cacattcacc tgttttggca tctcaccatt tttattgctg gctttaattt tcacggttaa
    82021 tggctgattg gggcgcattt tggtgggggt ttccagcgcc agatcgaggc gacggttttc
    82081 atcaccaagc ggcagatgca acaccccaac cgcgcgtttt ggcgtcgcgg agcgagattt
    82141 atcgccagga cgtaccacca gcgtacttaa atacagatca tgacgattcc aggttttatc
    82201 gaccggaatc gtcagatcca gcccttgagc cggaacatca atctcttgcc accacaacgg
    82261 cccttcactg gactcgacca tcgcataacc tttacccgcc gttggcgcgg caatatgcaa
    82321 cttaatggta tcgccagggc gataactggc tttatccagt ttcagcgtga cacggtcggg
    82381 tcgcactgca ccacccccgt cgctgttatc ctgccagcta taaccagccc agaaacgcac
    82441 actactgacc gcttcattcg gcgctttaac ttccagacga taagcgcccc actctaccgg
    82501 gaaactgacc ttaccggttt cgtccgcttt cagatccaga gtttgttcat tttcgatcag
    82561 atctttttga tcaaactgtg actgccagcc ttcatattcc gaccagttcc agtagtaatc
    82621 gcggcgttcg cgaatcaggc gcacctgcaa gcccgacacg gcttttttca cgccttgcgc
    82681 atcgctataa acgatgtcaa aagcggcgtt actgccttca tcaacaatgg gctgtttcac
    82741 cgtgctgtcg gtgcgataat cgtaaaccga tttcgaggcg aactgcggac ggatccccgg
    82801 caatgcatcg gcaggccaga tagcctgctc agcacggcgc gtcaccgggc gaccgcccga
    82861 ttccagcaaa ctaccctgga aaataacctg taatggagaa tgtgtttcct tccactggct
    82921 ttctgtagaa acttcgccgc gccctttatc atccagcgtc aactgaactt catccagcgt
    82981 gcgggaaaga ttttcggcag ctatatcgcc gaattcaaaa ccaggtaagg ctgacacagc
    83041 ttcacgcagt gggcgcagga aaagttgccc ttgcaaagta ttaccattcg caagtgcacc
    83101 atacaggtag taccccacca cggagaattt cacttcatct ttcggcgtta gcggggtttt
    83161 ctcaccggtc agattcagcg ccatacgctc tggcataaaa tcttcgacgt ggaaatccca
    83221 catccgatac tggttatcgc ccgtgttagc gcgaatatgc cacataccgg ttgccgcatt
    83281 gctatcgagt ggccaggtaa agtggtagag gccattctcc ggctgactaa cgacgctcct
    83341 gagtacctgc ccgtcgggtt taatcacgtc taacttgatg ggttgatcgg gcaatgcttt
    83401 accgtctgca tcacgcagca aaccattgag gatgaccgtt tcacccgggc gataaagatc
    83461 gcgcgggcca aacatgaaaa actgtttgct atagcctggc gcgccagcaa tgttaaattc
    83521 cgctaagtcc agcgccggga gttttaaatc gagcagcgtt gtctgaccgt ttttacgcgc
    83581 cagcagtaat gccgcgtttt tatcattttc cagttgcaca tgcccctgag cgtcactggt
    83641 tgcctgagtc agagtctgcc ctttctcatt taataaagag acttcaattc cttgcagggc
    83701 cgcgccgttt tccagacttt gggtaaagat atccagacga ttgtgataac ggtgagctga
    83761 aacgccaata tcacttaacg taaacagcgt cgcgggatta ctgtaatcgt aacgtccagc
    83821 ctgattcatc acagccagat acacgcccgc ctgctgaagc ggtttgatat cgcccagcgg
    83881 cagcaataat ttttcacggg tgttacgcgc aggattgaga tcaaaccgtc cggtgtagac
    83941 cagatccgcc atctgcagca gtttatctga ctgccagttc gccagcgaat tgcggtattc
    84001 ccactggcta atgaaagcgg gcagtgattc tggtttcaca cggaagaagt taacatcgac
    84061 attgttaacg ttaagcgcca ttaccggcag cccttcaacg accttaccag gaagcaacga
    84121 accacgactg gcaaaaccga cgctgggttg gatatcgcgg gtagttatag ttttttcgtc
    84181 atctttacta aaggttgcgt tattgagcgc tttgacctcc ttgccaatag tgacgatcaa
    84241 atcacgtttc ggttcgaggt ggcgtaaacg cagctcttta agattatctg acagctccca
    84301 ggcaccatcc actttgccgc tttttttatc gacgacatga ataacgcgtg agaaatcctg
    84361 atccgggtcg agagggatgg agaacgtcag caccagcgtg gctgcgccat cgagttgaac
    84421 ttcagagaga tccagcaatg tcagcgcctt accggcactc tgttgggcca gtttttgtcg
    84481 ctccggcgcg gaaagttttg ctgaactcac gttttctgaa gaggccgctt tagtaacttc
    84541 agaaggcgca tcttttttca ccgctgttgg cgcgttatcg ttgttgtcgc accctgccag
    84601 cgccagcatt agcatgcagg cggctacgcg taactttttc atttttcatc cctgccacaa
    84661 tggcccgtta gcaacgtcga ataattatta tgcgtgagaa tttacgttat gtaattcagt
    84721 atcacgccca tacaatccga attttagtga gaattgtggc tcagacagcc aaatcagcct
    84781 cttttgcttg tcgcttttca ctaaacatcc gacaatttag cctaaccccg gcaaaaatgg
    84841 agatgcctat gtccacgaca tggtttgtag gagccgactg gctcgccgaa catattgatg
    84901 acccggaaat tcagattatc gatgcccgca tggcgtcgcc tggacaggaa gatcgtaacg
    84961 ttgctcagga gtatctgaat ggacatattc ccggcgcagt gttttttgat atcgaagcgc
    85021 tttctgatca cacttccccg cttccgcaca tgctgccgcg cccggaaacg ttcgccgtgg
    85081 cgatgcgtga attaggcgtt aaccaggata agcacctgat tgtctatgac gaaggtaatc
    85141 ttttctcagc cccacgagca tggtggatgc tgcgcacctt tggtgtagag aaagtgtcga
    85201 ttctgggtgg tggacttgca ggctggctgc gtgatgatct gctattagaa gaaggcgcag
    85261 tagagctgcc ggaaggagag tttaacgccg cgtttaatcc tgaagccgtg gtgaaagtaa
    85321 ccgatgtatt attggcaagc catgaaaata cggcgcaaat tattgatgcc cgcccggcta
    85381 cacgttttaa cgcagaagtt gatgaacctc gcccaggttt acgtcgcgga catattcccg
    85441 gtgcattgaa cgttccgtgg acggaactgg tacgtgaagg cgaactaaaa acgaccgatg
    85501 aactggatgc gatatttttt ggtcgcggtg tcagctatga caaaccaatt atcgtcagct
    85561 gcggttctgg tgtaacagca gccgtggttt tgttggcact tgcgacgttg gatgtgccaa
    85621 acgtgaaact gtacgacggc gcatggagtg aatggggcgc acgggcagat ttaccggttg
    85681 agcccgtaaa ataagctttt tacgggcaat aaaaaaccgc cgaatttggc ggttttttat
    85741 tgctggtctg gttcgcggcc tttccagcag gttgtattac cgtagtaatg caagcgcgtc
    85801 tcagcggaca caatactcgc cagtaactct ctttttgtca agtaaaagag agttattatt
    85861 gttctgttag tgtattatcc actgcggccc tttccgccgt ctcgcaagcg ggcgctggct
    85921 taaggaaagg atgttccgcg accgttaggg caagcgcgtc tcagcgcttg ctatcgcggc
    85981 aatatcgcca gtggtgctgt cgtgatgcgg tcttcgcatg gaccgcacaa tgaagatacg
    86041 gtgcttttgt atcgtactta ttgtttctgg tgcgctgtta accgaggtaa ataataaccg
    86101 aagtctcttc ggcgacaatt tactggtggt taacaacctt cagagcagca agtaagcccg
    86161 aatgccgccc tttggggcgg catattttag attatccggt tctgtttaaa gtcacgcaaa
    86221 aaaccacccc agcgacgttc atagaatggc gcaatatgtt cggtaataaa gtggctaatt
    86281 cctttttccc cttttttcac ctgacaaata tcgatgggtt catcaccagg taatgtatcg
    86341 gtcgctacac ttcccgccac ctgaataatt tcttcgatat caccatcggc ttcaatgcca
    86401 ataagtaaat taggctgtgc ctcttcgttc tctttaattg aacaaataaa agcacgcttc
    86461 accggcttaa tggttttaaa taaggtggta agtgaatcaa tcatttgcgc tggcggctct
    86521 gcgacttccg ataatatcag cgattcaccg ccttccagta cttcctggct actcagcgga
    86581 ttcccttctt caccaatcaa caaactgatt tcacgcggca taaactcttt accggttggc
    86641 agtttggcat taaggaagag cgtttcgcca agggtcatct caaacaatgt gcgaacgggc
    86701 attacgacaa atgcctgttc gtcttcaacc gcctgttgaa gtgcttctaa cgaggtaaaa
    86761 aaaggaatga cgctggtgcc gtcttctttt tcccagtgct gtaaatcaag cgcgctatct
    86821 tcaactactg cctcgccctg cgccgccgta ccaggcaccc agacggtgga ttccagtaga
    86881 gtacggaaaa aggccgggcg gtgcgccggt tcggttgctg ctttttccag caggtcttca
    86941 agttcgtttt ttgtttcgga cataagaacc acaattcatt caacgttcgg ggagcaagtg
    87001 cctgatgcgc cacgcttatc aggcctacaa gggagtcgca atctattgga ttttcgcaat
    87061 ttgtaggccg gataaggcgt ttacgccgca tccggcatat tagtttacgc cgttaacaga
    87121 ttagcaatcg tgcgcacacc aagtcccgta gcacccgcag accactgttc aaccggcgct
    87181 ttacggtaag tcgccgagca gtcgatatgc agccagcctt gctgatagtt ctcaacaaag
    87241 tgcgacagga agcccgcagc cgtacttgca cctgccggat acgccgcgct tccggtattg
    87301 ttcagttcgg caaagttaga cggcagctgg ctgcggtgga attccgccag cggcagacgc
    87361 cagaacggtt cgttctcttg tgaggcactc gccagcaaac gaccggcaag cgcatcgtca
    87421 aaactgaaca acgcgtgata atcattaccc agcgcagttt tcgccgcccc ggtgagggtc
    87481 gccgcatcaa tgatcagttc cggtttctgc gcactggcat caatcaggcc atcggccagc
    87541 accagacgcc cttcggcatc agtgttcatc acttcaactt ttttaccgtt gcgataggtg
    87601 atgatatcgc ccagcttgaa cgcattgccg ctgatcaggt tatccgcaca acagaggaac
    87661 agcttcacgc gcttgttcag tccgcgcgta atggcaaatg ccagcgcccc ggtaaccgtt
    87721 gccgcaccgc ccatatccga cttcatcgag tccataaacg cggtctgttt gatgctgtag
    87781 ccgccggaat caaaagtgat gcctttacca accaggcacg cgtacactgg cgcttcttta
    87841 tcgccagttg ggttgtaatc cagcgccagc aataccggag aacgttctga accgcgcccg
    87901 acagtgtgca gccccatata accttgctca cgcagatctt cgcctttggt gatccggtaa
    87961 gtcacacgat cccctgcgac gttgcagatc agatcaacag cacgctgtgc cagttgcgat
    88021 ggtcccagct cttctgccgg tgcgttgatg gtgtcacgca cccagtcaat gatcatcagg
    88081 cggttatcca gttcctgacg ctgggcatcg tccagctctg gccactccac tttacgtgtg
    88141 cctttcgggg ctttgtaacc ttgccagaat gcccagcagc gatccgcatc ccagccttca
    88201 ccgcttaact gaacatgctt aatgcccaga ccatcaacct tgcgcgccgc acgctggatc
    88261 aaccccagat cgtctgcccc gttcaaatgc agggtaatgc catcattatt aatgctgtaa
    88321 gttgcttttt ctccccagcg cacgtcggca ggttgggtag aaagggtaat tttcatcgct
    88381 tctgtcattt tagttatcct tattcgttta acagcaaaac gggctacccc caggcagccc
    88441 gttcattcac tcggcttcgt ccagccagac caacaaaatc gcttcgagga ttttctcgtt
    88501 cgatgcctgc gggtcgtcgt cgaaatcttc cagagcgcaa atccactgat gcatatcggt
    88561 gaatcgaacc gttttcggat caatatcggg atacgcatcg tacagtgctt cgccaatttc
    88621 gcggctatcg gtccacttaa gtcccatact aacctctgtt aatgctcacg cgcatggttg
    88681 atagtgtaac gcgggatttc gaccactaaa tcttcgtcgg taacgcgcgc ctggcagctt
    88741 aaacggcttt ccggctccag cccccaggct ttgtccagca tgtcgtcttc ctgctctgag
    88801 ctttccggca gcgagtcaaa accttcgcga acgatgcagt ggcaggtggt gcaagcacag
    88861 gatttttcac aggcgtgttc aatctcgata ccgttacgca gcgcaacatc gagaatggtt
    88921 tcaccgctat tcgcttccag aacagcgcca tcagggcaga gatcctgatg aggcaaaata
    88981 acaatctttg gcatattaaa cctcgtccac ggaatggcct ttcagcgcac gacgaaccga
    89041 ctggtccatg cggcgagcgg cgaaatcctg ggtttgtttg tctacgtttt taatcgcttg
    89101 ttcgatggcg tcaacatcat cgccctgcgc cacttcactc aggtgagcgg cagcatcgtc
    89161 gataacctga cgttctgcgg cgcttaacag cgcggcatca gcagccagcg caccgtgcag
    89221 actttccagc acacgcgccg cttctacttt ttgttctgcc agcattcggg cttttacgtc
    89281 ctgctcggca tagctcattg agtctttgat catcgaggcg atttcgctat cggtcaggcc
    89341 ataagacggt ttgacctgaa tagacgcctc aacgccggtg gatttctcca tcgccgtcac
    89401 gctcaaaaga ccgtcggcat cgacctggaa cgtcacgcga atatgcgcac cgccagccgg
    89461 tagcgccgga atacctcgca gcgcaaaacg cgccagcgag cggcagtcct gcaccagttc
    89521 gcgctcaccc tgcatcacat ggatagacat cgccgtctga ccatctttaa aggtggtgaa
    89581 atcctgggcg cgggccaccg gaatcgtggt attacgcggg atcactttct ccaccaggcc
    89641 gcccatcgtt tcgaggccca gcgacagcgg gatcacatcc agcaacagca tttcgctgtc
    89701 cggcttgtta cccaccagaa tatccgcctg aatcgccgcg ccaatagcga cgactttatc
    89761 cgggtcgata gaagtcagcg gtggacgacc gaaaaattcg cctactcgtt cacgcaccag
    89821 cggcacgcga gtagaaccgc ccaccatcac cacttccagc acttcatcag cttctacgcc
    89881 cgcatctttc agcgcgcgac gacaagccag taaggttcgt tttaccagtg gcgcgatcag
    89941 ttcattgaat tgttcacggc tgatttcgcc ctgccagccc gcaacgttaa cggtcacaga
    90001 gtccgcatcg ctcagcgcga ttttggccgc aatggcagca tcgagcagtt cacgctgaac
    90061 gcggttatcg ctacgatcag gaatgcccgc ctgctcgcga atgtaatccg ccagcagatg
    90121 gtcgaaatca tcgccgccga gcgcggaatc accgccggtc gccagcactt caaacacgcc
    90181 gcgacttaag cgcagaatgg aaatatcaaa cgtcccgccg ccgaggtcat aaacagcgat
    90241 cacgccttcc tggccggaat ccagcccgta ggcaatagcc gcagcggtcg gttcattaag
    90301 taagcgcaga acatgcagcc ccgccagacg cgccgcgtct ttggtgccct gacgctgggc
    90361 atcatcaaag tacgccggaa cggtgataac gacaccatcc agctcgcctg ccagggcttc
    90421 agttgcccgc gccgccagtg ctttgaggat gtccgcagaa acgcgcaccg ggttcagcag
    90481 ccccgccgcc gtttcaatca tcggcaggcc attctcgctg gcctggaatt gataaggcag
    90541 atgcggatag cgttgctgga tatcagccag cgagcgcccc atcaggcgtt taacagaact
    90601 aatggtgttg gcggtgtcga gcgctgcgtt agtacgcgcg tcataaccca ccgaatgccc
    90661 ttgctgttga tagtgaacaa cagacggcag caggtgacgg ccttcatggt cagctaacgt
    90721 ttcggcctga ccgctgcgca ctgttgccac cagcgagttg gttgtgccca ggtcaatacc
    90781 ggccgccagg cgacgctgat gcggcgcagc actcaaacca ggttcactaa tttgtaataa
    90841 ggccatgttt agcttccaga aattaaaaat cgagcagttt ttcttcgagt tgttcggcac
    90901 tgctccgcag tttatcgaga aaacgcagct tacgcacagt atccgccgcc gcgtcccacg
    90961 tctcgttgtc taactgttca accatcaact gatggcgggt atcaaacatc tttttcacac
    91021 gtttgataaa gctttccagc cgcgcttcat ctttcgcctg ttcgatctcg tccagttctt
    91081 cgcgcagttc cagctgttcc atcaggaacg cggtgtcgcg cacagtatgc tgctcgctgg
    91141 cgagatcaaa accgtgcaaa gaaagcaaat attccgcgcg cattaacgga tgacgcagcg
    91201 tttgccaggc ctggttaatg gtcgcggatt gctgtacggc ggcgagttgt tccgcctggc
    91261 ttccgctggc gaatttatca ggatgatact gacgttgtag atcctgaaaa cgcaggctca
    91321 gcgcctgggt atcgagttga taacgggcag gcaagccaaa gagggtgaag taatccataa
    91381 cattctcagg gctgcgatcc gccgcgataa cggcgaatca ggtaaaacaa accccacgcg
    91441 caggcgacca cggtggggtt atcggtatgc gcatcaaacg tggaagcttt cgccgcaacc
    91501 acactcatct ttgacgttcg ggttggtgaa tttaaaccct tcgttaaggc cttctttgac
    91561 gaagtccagc tgcgtaccgt ccagaaattg caggcttttg ccatcgacca cgactttcac
    91621 gcctttgtct tcaaacacga tgtcttccgg cgtcggttcg tcaacaaatt ccagtacata
    91681 agccatacct gaacacccgg aggttctcac gcccagacgc aggccaaacc ctttaccgcg
    91741 gttagccaga aaggtattta ctcgcgctgc tgcactgtcg ctcagtgtaa tcgacataac
    91801 caaacctcaa ctcttatttt gcttcacgtt tgcttttata gtccgcaatg gcggctttga
    91861 tcgcgtcttc tgccagaata gaacagtgaa ttttcaccgg cggcagttca agttcttcag
    91921 caatatcggt gtttttgatc gcctgcgctt cgtcgagaga cttccctttc acccattcgg
    91981 tgaccaggga gctggaagcg atagcggaac cgcagccgta agttttaaaa cgcgcgtctt
    92041 caatgatacc ttcatcgttg actttaatct gcaacttcat cacgtcgcca caggccggtg
    92101 cacccaccat gccgctgccg acgttctcgt cgttgttgtc aaaggaaccc acgttacgcg
    92161 gattctcgta atggtcgata actttttcgc tgtaagccat tataaattct cctgattccg
    92221 ataccgatta atgatgagcc cattcgatgc tgttcagatc cacgccctgc ttgtacattt
    92281 cccacagcgg agaaaggtca cgcagacgac cgatggattt acgaactaac tcgatggtgt
    92341 agtcgatctc ttcttcagta gtaaaacgac ctaaagagaa acggatagag ctatgtgcca
    92401 gctcgtcgtt cagccccagc gcgcgcagca cgtaggacgg ttcgaggctt gctgacgtac
    92461 aggcggaacc tgaagaaacc gcgaggtctt tcagcgccat aatcagcgac tcaccttcaa
    92521 cgtagttgaa gctgacgttg agaatgttcg gcgcaccgtg ttccaggtca ccgttcaggt
    92581 aaacttcttc gatatctttg atgccgttcc acagacgatt acgcaggccg cgcagacgtt
    92641 ccatctcggt cgccatctct tcttttgcga tgcgataggc ttcgcccata ccgacgatct
    92701 ggtgaacagg cagagtgccg gaacgcatac cgcgctcgtg accgccgcca tgcatttgtg
    92761 cttcgatacg tacgcgcggt ttacgacgca catacagcgc accaatacct ttcgggccat
    92821 agattttgtg accggagaaa gacatcaggt caactttcaa ctggctcaga tcgatcggca
    92881 gtttgcccac gctctgagtt gcatcaacgt gatagataat gccacgagca cggcacattt
    92941 cgccgatagc cgcgatatcc tgcaccacgc cgatttcgtt atttacgtgc atgatggaaa
    93001 caaggatggt gtcgtcacgc atcgctgctt cgagttcttt caggtcgata ataccgttac
    93061 gctgcggtgc caggtaagtg acttcaaaac cttcgcgctc cagctgacgg caggtatcca
    93121 gtaccgcttt atgttcggtt ttactggtga tgatgtgctt gccttttttc tgataaaagt
    93181 tggctgcacc tttgatcgcc aggttgtcag attcggttgc accagaggta aagacgattt
    93241 cacgcggatc agcgccgacc agatcggcaa tctgattacg ggcgatatct accgcttctt
    93301 cagcctgcca gccgaaacgg tgagaacggg aggccgggtt accaaaggtt ccgtccatcg
    93361 tcataaactg catcattttc tcggcaacac gcgggtccac cggcgtggtt gcggagtagt
    93421 cgagataaat cggtaatttc attgctctat aaactccgta catcactcaa tgcaaggaac
    93481 caggctaccg gctggatgta cgaccgtgtt tacggagtgt ttagcactcc ggcctgattc
    93541 tgaattcttt ttattaagcg cgtaacttaa cgtcgatcgc gtcttgtgtg cgggtgcgtg
    93601 gcgcgtcgtg agtatgctga cgaccagaca catccagcac ttcctggtta ttaaccagtt
    93661 cgcctaaagt aatgttattg agaaaaccgg taagacggtc gctcaaatca cgccacagcg
    93721 cgtgggtcag gcatttatcg ccgccctggc agccgccttt accctgacaa cgggtggcat
    93781 ctacagattc gtcaacggcg ctaatcacct cgccaacggc gatgctgctg gcatctttgc
    93841 ctaacagata accaccgcct ggtccacgta cgctggaaac cagaccattt ttacgcagac
    93901 gggaaaacag ttgttccaga taagaaaggg aaattccctg acgttcggaa atatcagcca
    93961 acggtaccgg gcccgcttca gagttgagcg caacgtcaag cattgcggtc acggcatagc
    94021 gccctttaga tgtcagtctc atgtcttact tcacctcaaa ctcgcccctg cccggggttt
    94081 tttattgtaa aagtgggggt attgcatagc agggtcaagt ctgacattcc cgagtaaatt
    94141 ggtcaactat ttacttgact gatttagtcg ggtatttaac cttcagtgcc atttttttat
    94201 cgtggcgttt gtacctgttg tcggatgcgg tgtgaacacc ttatccgacc tgggattccg
    94261 tgcacttaca ggcctgataa gacgcgttaa gcatcgcatc aggcaaccac tgttattcgg
    94321 ccttgttacc tttattctgc tgctcaatag aagccagaat cccgcgcagg atattcaatt
    94381 cctggctttc cgggcgcgca cgggtaaaca gacggcgcaa tttattcatc acctgtcccg
    94441 gatggttttc acggataaaa ccggttgcca gcagcgtttg ctccagatga ccataaaaac
    94501 gctccagatc atcgaccagc ggatacggcg tctcttcatg ctcgacctgc tcgccatttt
    94561 cctgagttgc cagccaggcc atgcgcactt cataggcaat aacctgaacc gccatcgcca
    94621 ggttcagcga actgtattcc gggttagccg caattgcgac atgataatgg catttctgca
    94681 actcttcatt ggtcaagccg acgcgctcgc gaccaaacac cagcgccacc ggggtatttg
    94741 ccgcttcagc gacgcttttc agaccgcatt cgcgcgggtc gagcatcggc cacggcagcg
    94801 tgcgggagcg agcgctggtg cccaccacca gactacaacc ggctaacgct tcgtcgagcg
    94861 tatcgacgat gtgagcatta ccaatcacat cgctggcccc tgctgccagg gcaatcgcct
    94921 gggagtcagg tttcactagt ggattaacca gccacagatt ggttaatccc attgttttca
    94981 tggcacgggc aacagaaccc atattgccgg tgtgtgacgt ctccaccagc acaattcgaa
    95041 tattttgcag cattgtcttt cttcatctaa agattattca cgcatcttat cataaaacga
    95101 agacagatgc cgatctcgct gctatactct gcgccgtttt cccgttcttt aacatccagt
    95161 gagagagacc gatgcatccg atgctgaaca tcgccgtgcg cgcagcgcgc aaggcgggta
    95221 atttaattgc caaaaactat gaaaccccgg acgctgtaga agcgagccag aaaggcagta
    95281 acgatttcgt gaccaacgta gataaagctg ccgaagcggt gattatcgac acgattcgta
    95341 aatcttaccc acagcacacc atcatcaccg aagaaagcgg tgaacttgaa ggtactgatc
    95401 aggatgttca atgggttatc gatccactgg atggcactac caactttatc aaacgtctgc
    95461 cgcacttcgc ggtatctatc gccgttcgta tcaaaggccg caccgaagtt gctgtggtat
    95521 acgatcctat gcgtaacgaa ctgttcaccg ccactcgcgg tcagggcgca cagctgaacg
    95581 gctaccgtct gcgcggcagc accgctcgcg atctcgacgg tactattctg gcgaccggct
    95641 tcccgttcaa agcaaaacag tacgccacta cctacatcaa catcgtcggc aaactgttta
    95701 acgaatgtgc agacttccgt cgtaccggtt ctgcggcgct ggatctggct tacgtcgctg
    95761 cgggtcgtgt tgacggtttc tttgaaatcg gtctgcgccc gtgggatttc gcggcaggcg
    95821 agctgctggt tcgtgaagca ggcggcatcg tcagcgactt caccggtggt cataactata
    95881 tgctgaccgg taacatcgtt gctggtaacc cgcgcgttgt taaagccatg ctggcgaaca
    95941 tgcgtgacga gttaagcgac gctctgaagc gttaatgact caggcgggtg atatcactca
    96001 cccgccctcg cctttcaggc gctattccga aatacttcct caccgcttta ctttctttcg
    96061 tcactctccc accatctttc gccgattaat ggatgataaa gaagtcgcaa ggaaaggtta
    96121 tggcgctgcc agtgaacaaa cgcgttctca aaattctgtt tattctcttt gttgttgcct
    96181 tctgcgttta tttagtgccg cgcgtcgcca tcaacttctt ctattatcct gacgataaaa
    96241 tatacggtcc cgacccctgg tcggcggaat ccgtcgaatt tacggctaag gacggtactc
    96301 gtctgcaagg ctggtttatt ccttcttcga cgggccctgc tgacaacgcc atcgcaacca
    96361 tcattcatgc tcacggcaat gccggaaata tgtccgccca ctggccgctg gtcagttggt
    96421 tacccgagcg taatttcaac gtttttatgt ttgattatcg cgggtttggt aaatcaaaag
    96481 gcacgccgtc cctggccgga ttgctggacg atacgcaaag tgccatcaat gtggtgcgcc
    96541 atcgcagtga tgtaaaccca caacggctgg tgctgttcgg gcagagtatt ggcggggcga
    96601 atattctgga tgttattggt cagggtgatc gtgaaggcat acgtgcggtg atcctcgact
    96661 ccacctttgc ctcttatgcg accattgcca accagatgat ccccggcagt ggctacttac
    96721 ttgatgagag ttacagcggc gaaaattaca tcgccagcgt cagcccgatc ccgcttttac
    96781 tcattcacgg taaagctgat cacgttatcc catggcagca cagcgaaaag ttgtatagcc
    96841 tggcaaaaga gccaaaacgg ttgatcctaa tcccggatgg cgaacacatt gatgcttttt
    96901 ccgatcgtca cggcgatgtt tatcgcgaac agatggtgga ttttatcctt agcgcattga
    96961 atccgcagaa ctaacccatg atcgctagca cgataatcat tcacaaaacc accttaagac
    97021 atgctaatcc actggtcaga acagtttaag atgagaaaaa ttctgtgatg cttgccaaca
    97081 tttctgatga ttagcattcc cttcgccatt tccctgagca aactttagct attcttatca
    97141 attatgctta tgggagatct acagatgatg cctacgcttg ctccaccatc tgtcctttcg
    97201 gctccccagc gccgctgcca gatcttgctg acgctctttc agccggggtt gaccgccacc
    97261 acggcaactt tcagcgagct taatggtgtg gatgatgata tcgccagtct tgatatcagc
    97321 gaaacaggac gggagatcct gcgctatcat caactcacac tgacgactgg ttatgacggc
    97381 agctaccggg ttgaaggtac agtgcttaac caacgtttgt gtttatttca ctggctacga
    97441 cgtggtttcc gtctgtgtcc gtcatttatt accagccgat tcacccccgc cctgaagagt
    97501 gaactgaagc ggcgcggaat tgcgcgtaac ttttacgacg ataccaatct acaagcgtta
    97561 gtgaatctct gctcccgacg gctgcaaaaa cgctttgaaa cgcgcgatat tcatttcctg
    97621 tgtctgtatt tgcaatattg tttgttgcaa catcacgctg gaattacgcc tcagtttaat
    97681 ccgctccaac gtcgctgggc ggaatcctgc cttgaatttc aggtagcgca ggaaattgga
    97741 cgccactggc agcgtcgggc gctccagcct gtaccgcctg atgagccact atttatggca
    97801 ctactttttt ccatgttgcg ggttcccgat ccactgcggg atgcgcatca gcgggacaga
    97861 caactgcgtc agtctatcaa acgtctggta aaccattttc gtgagctggg aaatgttcgt
    97921 ttttatgatg aacaggggtt atgcgatcag ctttataccc acctcgccca ggcgttaaat
    97981 cgcagtttgt ttgccatcgg tattgataac accctgccgg aagagttcgc ccgcctgtat
    98041 ccacgcctgg tgcgcaccac ccgcgcggcg ctggccggat ttgaaagtga atacggcgtc
    98101 catctttctg atgaggaaag cggtctggtc gcggtgattt ttggtgcctg gctaatgcag
    98161 gaaaacgacc tgcatgagaa acagattatt ctactgaccg ggaatgatag cgagcgagaa
    98221 gcgcagattg agcagcagct acgcgaacta acgttactgc cgctcaacat taaacatatg
    98281 tcggtaaagg catttttgca gacaggcgct ccgcgcggcg cggcactgat tattgcgcct
    98341 tataccatgc cgttaccgct cttttcacca ccgctgatct atacggacct gacgttgaca
    98401 acacatcaac aggagcagat ccgcaaaatg ctcgaatcag catgagggaa caactttcgg
    98461 gcgcaaaaac attgccggaa gcgccaccag cgccatcacc cagaacacgc cgtggccgag
    98521 atattgatac aggaaaccgg cgaaaacggt catgatggcg atactgccgc ccatcgcgac
    98581 ggcagagtaa accgcctgta aacggatgac ttcgctaccc tggcgagcag caatatagcg
    98641 catggcagcc aggtggcaga ccgtgaaggt accgcaatgc agaatttgca ccactatcaa
    98701 ccacggcaac gccgtcgttg ctcccataat gccccagcgc actacgccgc aaatcgccga
    98761 gatcaacagc atatcgcgtg cactacaacg gcggaaaagt ttattactca gcgcaaaaat
    98821 aatgacttcc gccaccacgc ccagcgacca caaatacccc accgccgagg ccgagtagcc
    98881 agctgcctgc cagtaaatgg cgctaaaacc gtaataggcc gcatgtgccc cctgcaataa
    98941 acaaacgcag gccagaaagc gccagttctg gcgaaccaac gccaaccacg cagaccagcc
    99001 ggtgctctcc tgctggcggc ttgccccttg tggctgaatc gtcggacgga tgagaaagcc
    99061 gagcagcatg gatgccacgc ccaacgtcaa cagcgcgagg atcacccgat aatcaaacat
    99121 actgaccagt ttgcccgtca gcgccgagcc aatgacaaac gccaccgagc cccacagtct
    99181 cactttgccg taatcaagcg ggaactgctt ttgccacgta ttcgccagtg catcggtcaa
    99241 cggtaccagc ggtgagaaaa agaggttaaa gccaatcatc accagcatta gccacgctac
    99301 gtgcgccccc gcccagaagg cgacagcaaa gagaagtgtc agcagtgcca gcacgcgcaa
    99361 ggcggaaatc aggcgggaag gatcgctgac gcggggcgcg atgagcaaac tcccgaggaa
    99421 acgggcaacc agacccgccc ccaataacag gccgatggtt tctggcgtta aaccaatccc
    99481 tttaagccag acgctccaga aaggtagaaa aatgccgtaa ctaaaaaagt atgtgaaata
    99541 gccgagcgcc aaccagcgcg tggattgcaa aaccatgagt ccctcccgtc aggaggcgtt
    99601 agtctggggt taatcgaatg ttggtgcaag ttgaaaaata agaatattcg agcctgcttc
    99661 ctgacggtta tcctgcatat caggaaatga caaaaaagtg cggcccacaa cacaacatgt
    99721 aaaaaagaac gatgaaacag gtgaaaatcg caatttattg aactgacaaa ctcatgtgag
    99781 acggataagg cgtgcatgtc gcattcggca ggaaacaata agcacattgt cagccatctg
    99841 cgttatgccg ttataccaga aacgaatatc tcaacgcctg gggcgtggcg aggtaccaga
    99901 gtgtgtatta cgtttaaatc acatcatctt gcaaagggat tggttatgaa ctcactacgt
    99961 tattttgatt ttggcactgc ccgccccgtt ttattattaa ttgcccgtat cgccgtggtc
   100021 ttaattttca ttatttttgg ttttcccaaa atgatgggct ttgacggtac ggtccaatat
   100081 atggcctcgc tgggcgcgcc aatgccgatg ctggcagcga ttattgcggt agttatggaa
   100141 gtgcccgccg cgatattaat cgtgcttggc tttttcaccc gtccgctggc ggtgctgttt
   100201 attttctaca cgctgggtac ggcggtgatt ggtcaccatt actgggatat gaccggcgat
   100261 gcggttgggc caaatatgat taatttctgg aagaatgtca gtatcgctgg cgcattcctg
   100321 ctgttggcaa ttaccgggcc gggggcgatt tctctcgatc gccgttagga aagatgccgg
   100381 atgtggcgtg aacgccttat ccggcatttt ataaattaca gcaacgcaac ccgcaacgac
   100441 atctctgaaa ttgttgattc ccctggtgca agcgcaatga ggtcaccacc ttccgggcga
   100501 tgatggtcat ccggcgcatg actcatcggt tccagacaga agaaatcaaa cgcatatcct
   100561 ttatcaaacg cagggtctga aacaaagatg aaataacacg gtgcaggtgg cgtcgtttcc
   100621 atgatgatgg catacccctc ctgcggctgc tcgatgcggg ccttaccatt ccatccggca
   100681 aaaccattgt ttacccactg gcgcggcaac ggcgcgagct ggttaaaatc cagctcctgc
   100741 ggtagctgct cgcaaaactc acccgccagc cactgctccc gctccagcca gtaaccgctc
   100801 gcctgtgcct gaatccgcgt ttgcggcgac aacggaaaat aaggatgcca gccggtacca
   100861 aatggcagcg tctctgcccc ttgattggtg acagcgagcg tcaccgtcag cgtatccgcc
   100921 gttaaatgaa atgcctggct tacccgatag tgataaacac cgctgagatg ttcatacacc
   100981 agacacaagc tatcatcgct gcgcgagaca cattgccact cgcccaacca gccatcgccg
   101041 tgtagatagt gcgcatccca ctcaacattc ggttgcagtt gatactcacg cccctgccag
   101101 acaaaacggt tgccgctcac ccggtttgca aatggtacca gcggaaaaca agaggcatcg
   101161 gttgccacac cgcttttttt accaggacgt agcagcggcg tcgtatcgcg ccagaagcct
   101221 tcgattacgc cgccctgatc agaaacgtcc agctttagcg gcccgtgaga taaggtatag
   101281 atggtcatcc gcagactcct taatccggga aattaatcac aactttccca catttgccgc
   101341 ttgccatcag tgcataagca tctcctgcct gttccagcga gaaacgatgg gtaatggcgt
   101401 tacgcggcca cagtttccag tccgttaaat cgtgggcgca tttttccata tggaacaaac
   101461 tggtcaccca ggagccaata atccgccgtt gatggtgcat caggtcagcg ctaacctcga
   101521 actcgacttt tccggtttca ccaatgtaaa ccacgcgtcc ccagtcagct gtggattgca
   101581 gtgccagtaa gcgacctgcg gcattaccgg aacaatcaag cgcaacatcc gcgccgccgt
   101641 gagtgagttc ggcgattatc tgcggcagac cttcggtggt cgctaaatag ccgtgatcca
   101701 tcactcctaa ctgtttcgcc atcgccagac gttccggcag catatcaacg ccgatgatcc
   101761 tttttgcacc acgacctttc gccagcatca tcgccatcat gccgaccggc cccagaccga
   101821 ccaccagcac gttatcgcta ccggaaactt cgccgcgcaa aatcccttca tacgctgtac
   101881 caacgccgca actgataaac gcaccatctt catagctcag cgcgtccggc agcaggatca
   101941 gatctttttc ttccgccagc aggtattcag catggccgcc gtcacgctgc cagccgtaag
   102001 ccgcttttcc ttcgccagta caagaaatag gaaaaccgcg acggcagttc gggcaaaaac
   102061 cacagccaga aatgtgatac accagcacgc ggtcgccctc tttaaaatgg cggcagcctt
   102121 gccccatcgc cacaatctgc ccgcacggtt catgaccgtt gataaatccc tggtataacg
   102181 gtttatcggg tgccgccgcc gtagcgcggt gctggtggta gatatagtgg acatcgcttc
   102241 cgcaaatccc ggaggatttc attttgatca gtacctggtt aatccccggc gtcggcaccg
   102301 caacttcccg cagatcgacg gtcgaatttc ctggtaaata agctgccagc atcgttttca
   102361 taaatccctc attaacaata cgattaattt tcatccctgc cgcacccgcg ccaggggcgt
   102421 taaggtttag cgtttcgctt tactactacg ctgggtcagc aagatatttg ccagcaccgc
   102481 caccacaatg atgacgccgc gcaccacctg ctggaaaaag gagttaatcc cgagcagcac
   102541 cagaccgtta ccgattagcg taatcaccag tacgccaagc agcgtaccga acaacgagcc
   102601 gcgaccgccg gaaagcgccg taccgccgac cacgaccgcg gcgatgacgt caaactccag
   102661 accgtttgcg gcacctgcgt taccggaacc gaggcgcgcc gccaacaaaa tgccggtcac
   102721 cgccgctaat aatcccgaaa gggtaaaaat aagaatgcgt acccgacgaa cgttaatacc
   102781 gcacaactgc gctgcagtgg cattaccgcc aacagcaaaa accgagcgcc cgaaggcggt
   102841 tttgcggcta atgaacacaa acagcgcaaa taacaccatc atgatcagcg cggataccgg
   102901 cacaccgaga aattgtccgc ccagccagtc cagcacttcg ttttcgttaa ttggcactgg
   102961 caaggcgttc gtcataaaca gccccattcc gcgcagggcg ctccataaac ccagcgtggc
   103021 aacaaaactt ggcacgttaa acacgccgcg cagcaccccg gcgagcgttc ccatcagcgc
   103081 acctaacagc aacaccagca gacaagcaat cgccagcgga acttcaaatt gcagcaaaaa
   103141 cgccaggcac actgaaacaa aagccaccat cggcccaacg ctgacatcaa tttcaccgga
   103201 gataataatc agcgtcatcg cccaggcggc gatcccgatg gtggcggcat cgcgcagcac
   103261 gttcatttgg ttattcaatg agataaagcc aggcgcattc agggagaaga ccagataaag
   103321 aatggcaatc accaccagca aaccgatctc attaatatgg cgactgacaa attgtttgag
   103381 cgagacgctc ttgccctgcg gcaatggtaa tgacgaagca gacatcttca ggttcctcgg
   103441 taaaattcat cagtggacag aatggcggac atcagctcat ccacattgac cggcgagtga
   103501 aactcctgcg agaacgtgcc gtgctgtaat aacaggatgc ggtcacacac cagcggcaac
   103561 tcctccactt cactggagat aaacaccacg ctttttcctt cggcagccag ctcgcggaca
   103621 atacggtaaa tctgctgttt ggcttcgata tcgacgccgc gcgttggctc gtcgagcaac
   103681 aaaatctggc tggcggcata gacccaacga ccgatcacca ctttttgctg attgccgcca
   103741 gaaagcgtgc cgatgggcgt ttcgctactg gcggccttga ccgtcatccg ctgcatcacc
   103801 tcttcggtca ggcggcggat ggtggaccat tgcagcacac cgttggcgct gattttttgc
   103861 cgattggtca gcactgtatt ttcgtcaacg cccaaccagg gaatgatccc cgcttctttg
   103921 cggttttctg gcgtatagcc aatgccgcgt ttcagcatgt cgccgtaatc ggggcgcatg
   103981 attttctcgc cgttgataac aatttcgccc tgttcatacg tctccagacc aacaatcgcc
   104041 ttcagcaatt cactgcgccc tgcccccagc agaccagcaa tgccgagcac ttcgccacga
   104101 cgtagcgtaa aactgatatc ctccagcttg ggcttatggc gtaacgcacg gacttccagc
   104161 acggcttgat ccataatttc ctgaggggca accggcgcaa tatcaacgtg atcgcgcccg
   104221 agcattagcg acacaatatg atgcgtagag gtgttttcga gcatcacatc gcccgccacc
   104281 tgaccatcgc gcataacggt ggcacaggag gcaatgcggc gaatttcttc catccggtgg
   104341 ctgacataaa tcaccgccac gcccagtgcc gacatctttt tcaccgcgct gatcaccagt
   104401 tcaacttccg cactggcaag cgagctggtg ggttcatcaa gaatgaccac gcgcggctcg
   104461 cccttcatca cccgcgcaat ttccaccagt tgcttttgcg ccgggcttag cgttgaaaca
   104521 agttgttcag ggctaacgtc aacgcccagc gcctgtaagc aacgttgggc atcctgcgcc
   104581 atttgcaggt aatcaatcat gccgttgcgg cggggccact gaccgaggca gaggttttcc
   104641 gccactgtca gcccttccac cagacttaac tcctgataaa ccgcgcgtac ccccagttca
   104701 gcggcacggc gagtcagcgt agcttcgtca ccttccagtc gcgtctcgcc aatccagata
   104761 tcaccgctat ccggacgttc gctaccggta agcattcgaa tgagggtcga ttttcccgca
   104821 ccgtttttgc ctaacagcgc acgaacttcg ccttttttga gcgtgaagtt aacgttatcc
   104881 agcgcaacga ctccgggata acgcttattt cctgccacca cttttgctac cgggactgcc
   104941 tctgttgccg tgaacatagg gacctctgcg aatcagcgat tagggcagac catcaacgtg
   105001 cgttgccagc cactgtttac cgtcttccgt tttggtatag agatcgattg gcacctgaat
   105061 cactttttca ccgtcggctt gtttattgat aaccttcaat gtttgcgtaa aaacagcatt
   105121 gcccattttc ttaccagaaa tatccaccac cgctttcagc acctggttgt tttccagctc
   105181 ctgagcaatt tcagtggtca tatcagaacc gaaaacagca atttttccgg cctgattttg
   105241 attacgtacc gcttttaccg cgccgagtgt cgctccgccc gattccccca taatggcgtt
   105301 gagatccggc gtggagataa tcagtttttc accgacagaa atcgctttat ctaaaacagt
   105361 cccttcctga ttagcgacaa tttgcgcgcc gggaacgcgg gtttttaata cttcttcaaa
   105421 ccctttacga cgttgcacac aaacttcaaa ggcttcgcaa ttgatgacgg caattttcgg
   105481 ctggtcaatt ttgttggcaa taaaataatc ggcggcagcg ttacccagtt ttttaccaaa
   105541 ttccagcggg tcaccaacca gatatgccga gacatattta tcgacaccct tttgattaat
   105601 acaggtgttg tagcaaatca ccggaatacc cgcttcactg gcgcgacgaa cggtacggct
   105661 actgccattt tcagacactg ccgataaaat aatggcatcg acattacgcg ccacgagggt
   105721 atcaacaaag gtactttctt tcgaaatatc gccctgagcg ttagtttcaa ttaactgtac
   105781 ctgtactgaa gaatcttttg ccgcatcctg aacgccctga cgcactccgg cgtaatatcc
   105841 ctgggtatca aggtatattg cgccaatagt catttcttta tcagaagccc tggcaaatag
   105901 tgcgctaccc aatagtgtag ccattaataa taaattacgg gttcttgtca tttttttagg
   105961 catagtgcct cctgtagggt ttttatttac aacggcttat tttaattatt tgagcgtgag
   106021 cggcagcacg tgccgctcaa atattacagt taatagggtt tagtgaacgt agctaaaaat
   106081 aaaaggcatc acggtggtga ataatgccgc tttcggccag gctggattaa tcgccatcaa
   106141 ttcagcgcga gcagattcat agtgcgcaac ctcccctaat cccgcggccg ccagcatcgc
   106201 caccatcagg catttttctt tatgctgctg ttgtaaatcg ccatacagcg acaacaagtc
   106261 aggctgcgag acggcaaaga aatccgcctc gatactggtt ttcgccatct cttgtgccca
   106321 ctgtttcatt tcactaaaca gttgctgtgc agtttgttgt tcgcccagca gtcgcagcgc
   106381 cattccttgc cagaagagat aatcaaccgg ctgatcgttg taataactgt ggatgttaat
   106441 ggtgcgatcg ccggtcgccg ccagacgtaa acaacgcgtc gcttcagttt catcgccctg
   106501 cgcgttggcg catactgcct gccagaacca gatgtcgttg tcagtttgcc ccggtaaacg
   106561 gccttcgctt aaattctccg gataatgcag cgcggcatga agcagttcgc tggcctgctg
   106621 cggctctctg tcatcaagat gctgccaggc gcgtaataac tggttgagga taaactggct
   106681 ggtgaccttc ccttccccac cttcccacgg gtggaatttg cgcgtggcga gaatgtccgc
   106741 cgctttgtct gcctgacccg tgagatgcca caaattgagc agttctgcgg tcatgtcgtc
   106801 gcgtttcagc gcaatttcca gattatcttc cagacgcgcc agtcgtttct ccggtgtgac
   106861 accgcttaac ttatccagca aatcccgttc gaaaagcaga cgtgcatcct gcggcgcaag
   106921 ctgataagca ttatcaagat aacgcgcggc cagctcataa tcgtgctgct tattccacgc
   106981 atggatcgcc aacccgcgcc agccgtcggc aaactccggc gacatctcta cgcaacgctg
   107041 ccataaggca atggctttgc cgtagctacg cttgttgtag tagaagcagg ccagtaaatg
   107101 ccgggcaaac cagcactctt cgatactctc cagcgccgcc acttcttcca gcgtattcgg
   107161 gaaacggaca aactgcggga aggcatcaat agcttttgcg accagttctc cgcgttcagc
   107221 ttttggtagc aaactggctt gcaggtaaag cggtagcgtg cgctgacagt ccagtgcgtt
   107281 cagcatatct gccgccaggg cgggcatgcc ccagttaatc agttgcccgg cggtcatcag
   107341 ggcgttaacg tcgcgtccct gacaaagacc tcgccactgc gcgagggctg attcgctacg
   107401 accatcgaac cagttcagcc accacagagt ggcgttcagc ggataatcac gcagcagttt
   107461 ctcgcgctgc aaacgcgcgt tgtcctgacg accacttaac accagtagca ggttatgcag
   107521 gcaaagcact tcctgattgg ttgggcaggc gcgaagactt tgttggcaaa aatccagacc
   107581 agcgtcgaag ttaccattac gcgccgccag tcgtgccaga ccataatagc cgcccgcttt
   107641 actgttgccg ctccagaccg cacgccagaa atcctcttcg gcttgttgat attgcccctg
   107701 acgttcgtaa gcactggcgc gaatcaaact cgcctgtccg cactgcggat ttttgttcag
   107761 cgcatgtgcg cgtttcagtg cctgactggc atataccacc gcttgcggga aatctgcacg
   107821 gttatattcc agcattgcca gcgccagatt acagcgataa tccagcggat ccagcgccac
   107881 gccgcgcagg tagtaatcga acggtgaacg gctggcgtga tgatattgct ccagatgttg
   107941 accgataaac caggcttcat ctgtactggt aatgtcttgt gctgccagtg gcgctttggc
   108001 gacgtccggc aacggcaacg cttgcggctg atgttcatga taactcagta caatattgcc
   108061 gtcggcatcg gagagctcaa tggtcagcct ttcaggattg ataccgtgca acacgccctg
   108121 gatggcggtc gctggtgtca gggccacggc atcatcgagc aacgcgttgc atttgccgat
   108181 ttcgcggatc gccaggcggt atccgttcaa cggagagatg gcatacagcc cccactcaat
   108241 cccccgctca ctacgctgga gttttatcac cgcatcgcgg gaggcatttt gcaccatgcc
   108301 cagagaatga taaggcagga aatactgctc gaaacgcttc tcctcgtaag catcaagcca
   108361 ggtaaaatca ggctggttat cggcaaaaat accggtcatc agttcgatat acgggccgtt
   108421 attgtcagtc aggctcttat cccacgcctg gccaaattca ctgtgtcccc agctccactg
   108481 ttttttacct ggcgcaatat ggtggttggc aacgtgtagc aaaccaccat cttcatcgtg
   108541 acaccacgcg ccaacaaaat cgtactgtga tttttcagcc atatatgagg ttggaacggg
   108601 cacattttta tagcgagaaa tgtccactcc ggcggagtag tccactttgt agtaagtgcc
   108661 ggtggcgatg gggaaagcgg agacggcccg tttgccgtga tcaaacaccg ccgttacatc
   108721 cggcgggaag acgctctgat gcccttcccc ccctttcact gccgggttgg cccaccacaa
   108781 gaaatgacgc ggcgtggcgt tgccgttata gacgcgactg gcgatttcca gcgccgcccg
   108841 gtcagggcgc agggtgaaac ctgtcatcac ctgtaaaccg tgcatcgact ccgtttcgcc
   108901 gacccacacc gtctgtgcgc cgtcgtcatg ggcttcgagg gtgaaatcaa cgggcataaa
   108961 ggtggtcggg cgatggtgtt gcggccagtt aaactcaatc ccgccggaga tccacggccc
   109021 cagcagtccc accagcgccg gtttaatgac ttcattgtga taaacaaaat cgcgctgttt
   109081 cactttatcc cacgcgcgat gcacccgacc gcccagttcc ggcaggatca tcactttgat
   109141 gtagtcgttt tccagccaca ccgcctgcca ggatttcagg gttttctgct cgctcagcgt
   109201 atcggtcacg ccgtagggat aaaccgcgcc ggacgatccc tgataaacgc gattttccag
   109261 gaacatggga tgtatatcct gcggcccggt ttcataggtc gggatctcaa cgcgctcttg
   109321 ccacactttt actggagtca tggtgccctc aatattaaca agacatactg aattaaaaga
   109381 tttgtggcag tgtattgaac aatctggcaa tgttttcgcg gaataatcac gcaattaact
   109441 aaacaaggtt tagtgaagat gagagcctgc attaacaatc aacagattcg ccaccataac
   109501 aaatgcgtga ttctggaact gctgtaccgg caaaagcgcg ccaataaatc aacgctggcc
   109561 cggctggcgc aaatttcgat tccggcggtc agtaatattt tgcaggaact ggaaagcgaa
   109621 aaacgggtgg tgaatatcga cgatgaaagt caaacgcgcg gacatagtag cggtacatgg
   109681 ctgattgcgc cggaaggtga ctggacgctg tgtctgaacg tgacgcccac cagcattgag
   109741 tgtcaggtcg ctaatgcctg tttaagtccg aaaggcgaat ttgagtattt acagattgat
   109801 gcaccgacgc cgcaggcgct gctgtccgaa atcgaaaaat gctggcatcg ccaccgtaaa
   109861 ttgtggccgg atcgcaccat caatctggct ctggcaatcc acggtcaggt ggatccggtg
   109921 accggcgtgt cgcaaaccat gccgcaagcg ccgtgggcaa caccgattga ggtgaagtac
   109981 ctgctggaag agaagctggg tattcgggta atggtcgata atgactgcgt gatgctggcg
   110041 ctggcggaga aatggcaaaa taattcgcaa gtgcgtgatt tctgcgtaat caacgttgat
   110101 tacggcattg gctcgtcgtt cgtgattaac gagcaaattt atcgcggcag tttgtatggc
   110161 agtggacaga ttggccacac catcgttaat ccggatggcg tcgtctgcga ctgcgggcgt
   110221 tatggctgcc tggaaaccgt cgcctcgtta agcgcattaa aaaaacaggc gcgggtatgg
   110281 ctaaaatcac aaccggttaa tactcagctt aatcctgaaa aattgactac cgcgcagtta
   110341 atcgctgcct ggcagagtgg agaaccgtgg ttcaccagtt gggttgacca cagtgccaac
   110401 gccattggtt tgagtctgta taacttcctc aacatcctca atattaatca gatttggttg
   110461 tacggtcgca gttgtgcctt tggtgagaac tggcttaata ccattattcg ccagacggga
   110521 tttaacccgt tcgaccgcga cgaaggaccg agcgtgaaag cgacacagat tggctttggg
   110581 caattaagcc gcgcacaaca ggtactggga attggctatt tgtatgttga ggcgcagtta
   110641 cggcagattt gatggcgcga taacgtagaa aggcttcccg aaggaagcct tttttcaaca
   110701 gattaaccgt ttcgcttatg cgtaaaccgg gtaacgtgcg cagatgtcga gaactttacc
   110761 tttgatgcgc tcgataacgg cttcatcatt gatgctgtcc agcacgtcac acatccagcc
   110821 agccagttct ttcgcttcgg cttctttaaa gccacgacgg gtaatcgccg gagtacctac
   110881 acgaataccg gaagtcacaa atgggctctt cggatcgttc ggtacgctgt ttttgttgac
   110941 ggtgatgtta gcacggccca gagcggcgtc tgcttcttta ccggtcaggt ttttatcaac
   111001 cagatcaacc aggaacaggt ggttatcagt accgccggaa accactttgt agccgcgttc
   111061 gaggaacact tctaccatcg ctttggcgtt tttcgcgacc tgctgctggt aagttttgaa
   111121 ctcaggttcc atcgcttctt tcagagcaac cgctttaccg gcgattacgt gcatcaacgg
   111181 accgccctga ccaccaggga aaacggcaga gttcagtttt ttgtacagct cttcgctacc
   111241 acctttcgcc aggatcaggc cgccgcgcgg acccgccagg gttttgtgag tggtggtagt
   111301 tactacgtga gcatgaggaa ccgggttcgg gtagacgcca gcagcaacca ggcccgcaac
   111361 gtgcgccata tcaacgaaca ggtaagcacc gatgctgtca gcgatttcac gcattttcgc
   111421 ccagtcaacc acgccggaat atgcagagaa gccaccgata atcattttcg gtttgtgttc
   111481 tttagcttgt ttttccagat cggcgtagtc gatatgacca gtagcatcga taccgtaagg
   111541 aacgatgttg tacagtttac cggagaagtt aaccggagaa ccgtgagtca ggtgaccgcc
   111601 atgcgccaga ttcataccca gaacggtatc gcctggttcc agcagcgcgg tgtagaccgc
   111661 aaagttagcc tgggagccgg agtgcggctg gacgttagcg tagtcagcgc cgaacagttc
   111721 tttcgcacga tcgatcgcca gttgttcaac gatatcaaca tactcgcaac cgccgtagta
   111781 gcgtttgccc ggataacctt cagcatattt gttggtcagc tgagaaccct gcgcctgcat
   111841 tacgcgcggg ctggtgtagt tttcggaggc gatcagttcg atgtgctctt cctgacgtac
   111901 tttttcctgc tccatagcct gccacagttc ggcatcataa tcggcaatgt tcatttcacg
   111961 ctttaacatc cgcatctcct gactcagcta acaataaaat ttttggcctt tataggcggt
   112021 cctgttggac aacggcgaac agtataaccg aatcattgtg cgataacagg tcttgacaaa
   112081 ggaatttacg caaacgatta ccttcaggct acgcaaggct ttggagaata aagagcttgc
   112141 aaccggaaac ggatttcttt tcaggtttgt gatgcaaatt tttcacttca tcacattctt
   112201 tctgaaaaac accaaagaac catttacatt gcagggctat tttttataag atgcatttga
   112261 gatacatcaa ttaagatgca aaaaaaagga agaccatatg cttgacgctc aaaccatcgc
   112321 tacagtaaaa gccaccatcc ctttactggt ggaaacggga ccaaagttaa ccgcccattt
   112381 ctacgaccgt atgtttactc ataacccaga actcaaagaa atttttaaca tgagtaacca
   112441 gcgtaatggc gatcaacgtg aagccctgtt taacgctgtt gccgcctacg ccagcaatat
   112501 tgaaaacctg cctgcgctgc tgccagcggt agaaaaaatc gcgcagaagc acaccagttt
   112561 ccagatcaaa ccggaacagt acaacatcgt cggtgaacac ctgttggcaa cgctggacga
   112621 aatgttcagc ccggggcagg aagtgctgga cgcgtggggt aaagcctatg gcgtactggc
   112681 taatgtattt atcaatcgcg aggcggaaat ctataacgaa aacgccagca aagccggtgg
   112741 ctgggaaggt actcgcgatt tccgcattgt ggctaaaaca ccacgcagcg cacttatcac
   112801 cagcttcgaa ctggagccgg tcgacggtgg cgcagtggca gaataccgtc cggggcaata
   112861 tctcggcgtc tggctgaagc cggaaggttt cccgcatcag gaaattcgtc agtactcttt
   112921 gactcgcaaa ccggatggca aaggctatcg tattgcggtg aaacgcgaag agggtgggca
   112981 ggtatccaac tggctgcaca atcacgccaa tgttggcgat gtcgtgaaac tggtcgctcc
   113041 ggcaggtgat ttctttatgg ctgtcgcaga tgacacacca gtgacgttaa tctctgccgg
   113101 tgtcggtcaa acgccaatgc tggcaatgct cgacacgctg gcaaaagcag gccacacagc
   113161 acaagtgaac tggttccatg cggcagaaaa tggcgatgtt cacgcctttg ccgatgaagt
   113221 taaggaactg ggtcaatcac tgccacgctt taccgcacac acctggtatc gtcagccgag
   113281 cgaagccgat cgcgctaaag gtcagtttga tagcgaaggt ctgatggatt tgagcaaact
   113341 ggaaggtgcg ttcagcgatc cgacaatgca gttctatctc tgcggcccgg ttggcttcat
   113401 gcagtttgcc gcgaaacagt tagtggattt gggcgtgaaa caggaaaaca ttcattacga
   113461 atgctttggc ccgcataagg tgctgtgatt tgatgttgcc ggatggacac atccggcaac
   113521 ccttgacgcg ttttaaattg ccgcgtcgtc ctcttcaccg gtacggatgc gaatgacccg
   113581 tgccacgtcg aagacgaaga ttttaccatc accgattttg ccggtttgcg ccgtgcgaat
   113641 aatggtatcg acacaggtat cgacaatgtc gtccggtacg acaatctcaa ttttcacttt
   113701 cggcagaaaa tccaccatat actccgcacc acggtacagc tcggtatggc ctttctggcg
   113761 gccaaaacct ttcacctcag tgaccgtcat gccggtaata ccgacttcag ccagtgcttc
   113821 gcggacatcg tccagcttga agggtttaat aatcgcatca atctttttca tgctattcct
   113881 tgaaaaggtc gcctgtcttt tgatctgcta aacgtaacac ataacgccaa ttcattcctt
   113941 gaaatcgttt gcatccagct cgtttcggga aagcagttta taaaattctg tccggttgcg
   114001 ccccgccatt ctcgccgcgt gggtgacgtt gcctttggtg atttgcagca gcttacgcaa
   114061 atagttgagt tcaaactgat tacgtgcctc aacaaaggtt ggcagcgccg tattttcacc
   114121 ctccagcgcc tgctccacca gcgcatcact aattaccgga gatgaggtca gcgccacaca
   114181 ctgttcaatc acgttgacca actggcgcac gttgcccggc cagcttgcag tcatcaggcg
   114241 tttcattgca tcggtggaga acgcgcggac aaacggttta tgtcgctctg ccgcctggcg
   114301 caacaggtga tttgccagta gcggaatgtc ttctgtgcgc tccgccagtg ccggaatttt
   114361 caggctgaca acattgaggc ggtaataaag atcttcacgg aattccccac gcgccatcgc
   114421 ttttggcagg tcgcggtgag tggcggaaat aatccgcacg tcaatatcaa tatcgcggtt
   114481 actgcccagc gggcgcactt tacgctcctg caacacgcgc agcagtttga cctgcaacgg
   114541 tgcaggcata tcgccaatct catcaagaaa tagcgtaccg ccttccgccg cctggaataa
   114601 accttcgcga ttgctgacag cgccagtaaa cgcgccacgt gcatgaccaa acagctccga
   114661 ctccagcaat tgctcgggta atgcgccaca gttaatagca ataaatggct tgctgttgcg
   114721 cgggctggcg ttgtggatag cctgggcgaa aatctctttc ccggtgccgc tctggccgtt
   114781 aatcaaaacg ctaacgtctg attgtgccac cagccgcgcc tgttccagca agcgcagcat
   114841 cagcgggctg cgggtgacaa tcgcctcgcg ccaacgttcg tcggtggctg gcgcggattg
   114901 ttccagcgca tcgtcaattg cctgatatag cgcatcttta tcgacaggct tggtgagaaa
   114961 actgaacacg ccctgctgtg ttgcagcaac ggcatcagga atagaaccat gcgcggtaag
   115021 aataattact ggcattcccg gctgcacttt ctggatttca gcaaacagct gcataccgtc
   115081 catttcatcc atccgcaggt cgctgatgac taaatctact ttttcgcgat tcagtacccg
   115141 caatccttca gcaccacttt ccgccgtgac cacactgtag ccttcgctgg tcagacgcag
   115201 gccaagcagt ttcagcaatc ccggatcgtc atcgaccagt aataaatgcg caggtttatg
   115261 gctcatcagg agtgacctca tcggtggatg gcgcgggctt ttcactctcg tgcggcgtat
   115321 ccggcgagaa atttccagcc ggtttgcggg tcgagagctg gcgttcaata tcggtcaggt
   115381 tttccagctt gcgagtagtg agttccagtt gctgttgtag aacgtgatgt tgctggcgca
   115441 aagtatccag ctcgctgtcg ctggactgct ggagtttgct gtagcgttgg cgctcttccg
   115501 ccagttgcag ttgcagcgcc tgaccgtcgc gccaaagttg atacagtggg cgaacctgtg
   115561 ccgggatctc ggtacttagc gcatcaatgc gcgcgaccag ctggcggcgc tcatacggcg
   115621 taattttggc gtcggcgagc aaaatccctt gtttaaaggt attttgccag ttgccgtcgt
   115681 catattggcg ggcttgctga cgcgactgcg caggcattaa acgatcagca caatccatcg
   115741 cccgcagcca gtaaagcgga ttggtttcgg ttgatttacc ttgcagcgcc cagatgtcgc
   115801 tacattcagt agaaagatag tcagccagtt gataaaccgg aattttttct tctgctggcg
   115861 tatcaatggc tggcctattg tgactctgca cgcaacccag caatgccaga catggcagcc
   115921 ctgccagcca cagccgtcgg ggcaataatc gttgaaaaat gtgtcgcata ttcaccagac
   115981 ttaaagccta tcccagtggg cgtaattgtt gcaggcagtt tggacatgga cagcgcggag
   116041 aaaccggagc gtacatgtcg tacgtgaaga tttcgagcac tgcccggggc cgaactgaca
   116101 aataaaatag cctgatggga tgggctgtta gcattatttc gtgtttttcg acgacggtaa
   116161 ttcaatgcgg aaacaaacgt cttgcccgct ctcgtcgacc agatacagtt ccccttgcat
   116221 acggcgaata caatccctgg caatgcttaa tcccagaccg ctgcccttca ccgccccttt
   116281 tcgctggtgg cttccctgaa aaaagggttc gaagatcatg gcgcgttcct cttgcggaat
   116341 gggcgtgcct gtattgatga catcaatata aacccgcgca ccatgtaaac tgctgcgaag
   116401 gcaaatgtta ccggattcag ccccgtagtg caccgcattg gagtaaagat tatccagtac
   116461 gctcatcagc agcattggct ccgccaggca agctgttgct ttgagatcaa cgtcggtatg
   116521 catcatttta gcccgtgcgg gcaggctatg agcagaaacc aatgtctcca ccagcggtgc
   116581 taactcaaca ttctccagtt ccaccgcact gtccgcctgt ttacggttgt aatcaagcag
   116641 ttgttcgatc agtttttgca aattgcggct gctgctatca agaatgctca ccacctcttt
   116701 ttgctctggc gtaagcggcc cgacaacctg atcagccagt aattcagtgc cctcgcgcat
   116761 actcgccagt ggcgttttta attcatgaga taaatgtctt aaaaattgat ggcgttggga
   116821 ttccagccat gacaggcgct cacttaacca aagaatacgt tgcccaaccg agcgtaactc
   116881 gctcggtcca ctgaacgaga cgctattgcc cagagaacgc ccttccccca gccggttgat
   116941 catgcgctcg atatttttca ccggaccgat aatcatcctc gtgaaaagca gtaccatcac
   117001 cagactcacc agaaatagca ccagcgattg ccaaccaaaa tattgcccac gttcggcgat
   117061 ttcacgctga agttgctgcc cacgagagaa caccactgtg cgcgtggcct gcaccatttc
   117121 ggtattggca ctggcaaagg cttccagacg cgcggcggca gcagcatcgg gaccgctgtt
   117181 gttacactga agttgagcca gattgttcaa atcctgacgt aatgcctggt agagtttatc
   117241 gtccggcagc acgcctgcgt gggcatcgag catttcgctg taacgcttgc gctggctttg
   117301 ataaaccttc gcaagcgtag ggtcgtccag cacgcagtac tgacggtagc tgcgctccat
   117361 ctccagtgcc gcgttggtca tcgcttcact gcgccgggca tcaataagcg tagtgcggtt
   117421 aaccagcgcc gcctgatcgc taagtgcatt caggctttgc caggcttgcc atgccagcac
   117481 caacaggggc agcagaatca gcaaaaatgc cagcattacc agttgtcgta atgagcgggg
   117541 aaaaacgggc cagcgtttca aggcgttact ctcgtcagac gcgaatagcc tgatgctaac
   117601 cgaggggaag ttcagataca acaaagccgg gaattacccg gctttgttat ggaataaggc
   117661 ggtgcctaac tcgacgtttc gcccgatggt tgatatagct aagctgatat cagaagttgg
   117721 acggcaggca ccttgttgtg cgtcattcga attttatgta gcacgtcccg aaggggctga
   117781 cataagtcgg tgaatgagcc actgcttact attatgcagt aactgtgcca ataaagaaaa
   117841 tagtttggta acatactgat tatacgctgc tttgaggggt ttatggcttc tccgctattt
   117901 gaatgtaaat cagccactgt gtcgctaaaa agagacaact taagataaac ttattagata
   117961 atattaaaat caatgagtta agtgtcacca aaaagcgaca cggcaaacca cccattgtcg
   118021 tgatttaaag acacaaaaaa gctcccgaag ttgggagctc ataatagcgg ttggtgctta
   118081 atgccggatg cggcgtgaat gcctcatccg ggctgcaata ccaatgggtt gacgacttac
   118141 cccaactgct tacgtgcatt gcggaaaatg cgcatccatg ggccatcctc gccccagttt
   118201 tccggatgcc aggagttgct gacagtacgg aaaactcgtt ccgggtgcgg catcataatg
   118261 gtgactcgac cactttcagt cgtgaccgcc gtaataccgt tcggtgaacc gttcgggtta
   118321 gccgggtagg tttcagtgac tttgccgaag ttatcgacat agcgcagtgc caccagccct
   118381 ttgctttcca gtgccgccag atgcgccgca tcacgcactt ccacgcgccc ttcaccatga
   118441 gacacagcaa tcggcatctg cgagcccacc atcccctgca acagcagcga cgggctttgg
   118501 gttacttcta ccagactgaa acgcgcttca aagcgatcgg aggtgttacg cacaaaacgt
   118561 ggccacaact cgctacccgg gatcagttca cgcagattag acatcatctg gcaaccgtta
   118621 cataccccca gcgccagcgt ttgcggacga tggaagaagg ttgcaaactc atcgcgtaca
   118681 cggtcattga acaggataga cttcgcccaa ccttcaccag cgcccagcac atcaccgtag
   118741 gagaaaccac cacacgcgac cagggcgtgg aaaccctcca ggcccgtgcg tccagccagc
   118801 agatcgctca tatgcacgtc gatagcatcg aagcctgcac ggtggaaagc tgccgccatt
   118861 tcaacatgcg agttcacgcc ctgctcacgc agcacggcaa ctttcgggcg cacgccagtg
   118921 gcaataaacg gtgctgccac atcttcgttg atatcaaacg acagtttcac attcaggccc
   118981 ggatcggcgt cgtttgattt cgcctggtgt tcctgatcgg cacactccgg gttgtcacgc
   119041 aggcgctgca tctgccaggt agtttctgcc caccagacac gcagcgtggt gcggctttcg
   119101 ctaaatacag tctgcccgtt ggcagtaatc acaaaacggt caccggaaac cgcctgccca
   119161 acataatgga cgcaatcagc aagcccatgc tgtgccagta ccgcttcaac ggcttcacga
   119221 tcagcagctc gaacctgaat caccgcaccc agttcttcgt taaacaacgc cgccaggcga
   119281 tcgtcaccca gagaggcgat atccgcgtca atgccacaat gaccagcaaa ggccatttcc
   119341 gccagcgtta ccagcaggcc gccatcagag cggtcgtgat acgccagcag cttacgctgt
   119401 gcaaccagcg cctgaatcgc gtcatagaag cctttcagtt gggcaacatc gcgtacatct
   119461 gccggtttgt cgccaagctg acgataaacc tgcgccagtg ccgttgcgcc cagcgcgtta
   119521 ttgcctttgc ccaaatcaat cagcaacagt gcgttatctt cggtagaaag ctgcggcgta
   119581 atggtgtgac gtacatcttc cacgcgggca aatgcggaaa tcaccagcga caacggcgac
   119641 gtcatttcgc gctcttcgtt accttcctgc cagcgggttt tcatcgacat agagtcttta
   119701 cccaccggta tcgtcaggcc cagcgccgga caaagttctt cgcccacagc tttaacggct
   119761 tcatacaggc ccgcatcttc accagggtgg cctgccgccg ccatccagtt ggcggaaagt
   119821 ttaatgcgtt tgatatcgcc aatttgtgtt gcggcgatgt tggttagcgc ttcaccgact
   119881 gccagacggg cagaagcggc gaaatccagc agcgcaactg gcgcacgttc gccaattgcc
   119941 atcgcttcgc catagtagct gtcgaggctg gcggtagtga ccgcgcagtt agcgaccggc
   120001 acctgccacg gccccaccat ctgatcgcgc gccaccatgc cggttacgct gcggtcaccg
   120061 atggtcacca ggaaagtttt ctccgccacg gtcggcagat gcagcacgcg tttcaccgcg
   120121 tcagcgatgg tgatcccttc acgggccagc gcgtcgcctt tcgctttcag cgtttgcaca
   120181 tcgcgggtca tcttcggcgt tttgccaagc agtacgtcca gcggtagatc aatcggctga
   120241 ttatcaaaat gacgatcgtg cagagaaaga tgcagttctt cggtcgcttc accaatcacc
   120301 gcgtacggtg cgcgttcacg cttacacagt tcgtcaaaca gcggtaactg atcggcagca
   120361 actgccagca cgtagcgttc ctgggattcg ttacaccaga tttccagcgg gctcatgcct
   120421 ggctcgtcgc tcagaatatc gcgcagttcg aatttaccgc cgcgcccgcc gtcgctcacc
   120481 agttccggca tggcgttaga aagaccgcct gcgccaacgt cgtggataaa caggattggg
   120541 ttggcatcac caagctgcca gcaacggtcg atcacttcct ggcagcgacg ctccatctcc
   120601 gggttgtcgc gctgtacgga agcaaagtcg aggtcggcat cagactgacc agatgccatg
   120661 gaagacgccg cgccgccgcc aagaccgatg ttcattgccg ggccgccgag aacgaccagc
   120721 ttcgcaccaa cgttgatctc gtctttttgt acgtgatcgg cgcgaatgtt gccgatccca
   120781 cccgccagca tgatcggttt gtgataaccg cgcagctctt cgccattgtg gctgttcact
   120841 ttttcttcat aagtacggaa gtagccgttc agtgccgggc gaccaaattc gttgttaaac
   120901 gccgcgccgc ccagcgggcc ttcggtcatg atgtccagcg cggtgacaat gcgctcaggc
   120961 ttaccgaaat cttcttccca cggctgttca aagcccggaa tacgcaagtt ggatacggag
   121021 aaaccaacca gaccggcttt cggctttgcg ccgcgcccgg tggcaccttc atcgcggatt
   121081 tcaccgccag aaccggtcgc cgcacccggc cacggagaaa tcgccgtcgg gtggttgtgg
   121141 gtttcaactt tcatcagaat atgcgccggt tcctgatgga aatcgtagcg gcccgtttcg
   121201 tggtcagcaa agtagcgacc cacttcagaa ccttccatta cagcggcgtt atctttataa
   121261 gcagagagaa cgtggtctgg cgtggtttcg aaggtgtttt tgatcatctt gaacagcgat
   121321 ttcggctgct gttcaccgtc gataatccag tcggcgttaa aaattttgtg acggcagtgc
   121381 tcggagttcg cctgcgcgaa catatacagc tcgatgtcgt tcgggttacg acccagcttt
   121441 gtgaacgcat cctgcagata gtcaatttca tcttccgcca gtgccaggcc aagacgcagg
   121501 ttagcgtcga ttagcgcctg acggccctgc cccagcaaat ctacgctggt gaccggagtc
   121561 ggttgatggt gtgcaaacaa ctgctctgca tcatctaaag caaaaaagac cgtttccatc
   121621 atgcggtcgt gcagttcagc ggtcacctgc tgccattgtt cattggtcag cgtaccggct
   121681 tctatatagt aagccatgcc gcgctcaagg cggtttacct gttgtagacc gcaattatgg
   121741 gcgatatcgg tcgctttcga agaccaggga gagatggtgc caggacgcgg ggtcaccagc
   121801 aggagtttgc cttgcggggc gtggctggcg agtgccgggc catatttcag caggcgttca
   121861 agttgtgcgt gctcatcatc gtttaacggc gcattgaggt cagcaaaatg gacatactcg
   121921 gcgtaaatag tgtgaaccgg gagcctggca gcctgaaaac gtgccagcag tttgttgatt
   121981 cggaatgccg acaatgcagg cgaaccacgc agaatttcca tcataagtct ctcgtcttct
   122041 aagctttcgg tgtacccaag ggggggaaac gggcgtcatt ataaagaatc tgatgcgctg
   122101 acgaaaccgt ttgcgtggaa ataaaatcac catcgtgaat tagcaacgcg tgccgccaat
   122161 ggctgtaata agttgccatc tggcgcaggt ttacgcaaaa tgccgctcat ttatgagtaa
   122221 acctttcact attattacgt tttttcaagc tgggacgcgc acgacacaga gaattaacta
   122281 attgaaaaaa ttaaagatta attatctgtt catcggcatt ctggcactgc tgctcgcggt
   122341 cgctctctgg ccatccattc cctggtttgg taaagccgac aaccgtatcg ccgccattca
   122401 agcgcgggga gagttgcgtg tgagcaccat tcatactccc ctgacttata acgaaatcaa
   122461 cgggaaacct tttggcctgg attacgaact ggcgaaacag tttgccgatt acctcggtgt
   122521 aaaactgaaa gtgaccgtgc ggcagaatat cagccagctg tttgacgacc tcgataatgg
   122581 taacgccgac ctgctggcgg caggactggt ctataacagt gagcgggtaa aaaattatca
   122641 gcctggtcct acctattatt ccgtgtcaca acaactggtt tataaagtgg gtcagtatcg
   122701 cccacgtacg ctgggcaacc tgacggcgga gcaactcacc gttgcaccgg gtcacgtggt
   122761 ggttaacgat ctccagaccc tgaaagacac aaaattcccg gaattaagct ggaaggtaga
   122821 cgacaaaaaa ggctctgcgg aattaatgga agatgtcatc gaaggaaaac tcgattacac
   122881 cattgctgat tctgtcgcca tcagcctgtt tcagcgcgtt cacccggaac tcgccgtagc
   122941 gctcgatatc accgatgaac aaccggtgac ctggtttagc ccgttagatg gcgataatac
   123001 cctttccgcc gccctgctcg acttcttcaa cgaaatgaat gaagacggta cactggcacg
   123061 cattgaagag aaatacctgg ggcatggcga tgattttgat tacgtcgata cgcgcacatt
   123121 tttacgcgcc gtcgatgcgg tactgccgca gttaaagccc ctgtttgaga aatacgccga
   123181 agaaattgac tggcgtttgc tggccgctat tgcttatcag gaatcgcact gggatgcgca
   123241 ggccacttca ccgacgggtg tgcgcggcat gatgatgtta accaaaaaca ccgcgcaaag
   123301 cctcggcatt acggatcgta ccgatgccga acagagcatc agcggcggcg tgcgttattt
   123361 acaggatatg atgagtaaag tgccggaaag tgtgccggag aacgaacgga tctggtttgc
   123421 cctcgccgcg tacaatatgg gctatgcgca tatgctggat gcccgcgccc tgacggcaaa
   123481 aaccaaaggt aatcctgaca gttgggctga cgtaaaacag cgtctgcctt tacttagcca
   123541 gaaaccctat tacagcaagc tgacttacgg ctacgctcgt gggcatgaag cctacgctta
   123601 tgtcgaaaat attcgtaaat accagattag cctggtgggt tatctgcagg agaaagagaa
   123661 gcaggctaca gaagcggcga tgcaactggc gcaggattat ccggcggtat cgcctacgga
   123721 gctgggcaaa gagaaatttc cttttctctc gtttctttcc cagtcgtcat caaactattt
   123781 gacccactct ccctctctgc tgttttccag aaaagggagt gaagagaaac aaaattaatc
   123841 tgtcgaggat tgcgcttttt tctgcgcttt aatttcctgg cggcgcatgc gaaagaagtc
   123901 actgagcaac gccgcacact catccgccag tattccttcc gtaatttcca cccggtgatt
   123961 catacccgga tgatgcagca catccattaa agatcccgca gcgccagttt tcgcgtcacg
   124021 cgcaccaaag accacgcgac caatgcgact gtggatcatt gctccggcac acattacaca
   124081 gggttcaagc gtgacataca acgtggcgtc gatcagacga taattttgca tcaccagacc
   124141 gccctgccgt agggccatga tttctgcatg tgcggtggga tcatgtcgac caatcggacg
   124201 gttccagcct tcgccaataa cacgattgtt atgcactaat accgcgccga ccggtacttc
   124261 ccgctcatcc caggcacgct tcgccagcgt cattgcatga cgcatccagt attcgtagct
   124321 aaattcgact tcagacaaaa agaaaactcc ggttataaaa gcgcggcgca ttatacacgg
   124381 acgctatgct ttactctatt ccagttgctg gagttcaccg cgcggggtta cccgccagcg
   124441 atgctggcaa aagtaaagca gcgggttgtc ctggttactg tcgctatagc cactgtacag
   124501 ccgcagcggc gtgccgattt tgcgctccag ttgcgcgacc ttctcatgcc cgaggcaacg
   124561 catcgtcaat acccaaccac catagccacg ctgaatctga ctggcgataa gattaacccg
   124621 cggcagccag ggcgtatcga aataaaccgc ttcaaccagc ggctgcggag agccggtaat
   124681 caaccagata tcagcatcgg aacttaacag gtaggtggtt aatcgctcct gaaccagcgg
   124741 aaaggcggta acattgtcac gaaaccagcg tacgaaatcg gcctgcaacg cctgcaaacg
   124801 cgcttcattg tgaccaaaag tgcatcccca cagaagcaga ctcatcggcc agcgtgccgc
   124861 acgacctttt atcaataacg caatggctat gatcggcaac aacggcagaa caagtaacgc
   124921 attcagcggt tggcgacgca gtaaataacg caaaaaactg ccgaacatat cctgctgatg
   124981 caatgttcca tctaagtcaa aaaacaccac acgacgctcg tgagttgcca aaccatactc
   125041 ctctggactg aaacatcctg attaattttc gctactacat agcctaacag atagatcatc
   125101 acttttccgg caacaatcga ccgcatcatg gctaactgga atttttaatt catggcaatt
   125161 agcggcaatg gaatataaaa ttcactcgcg tgtgtctcat attgcctgtt gtcgccatta
   125221 tttcatcgcg aggaaagata tgaacggctt acttcgtatc cgtcagcgtt accaggggct
   125281 tgcccagagt gataaaaaac tggcggatta tctgctgcta caacctgata cggcgcgcca
   125341 tttaagctct cagcaactgg ccaacgaagc cggagtcagt cagtccagcg tcgtgaagtt
   125401 cgcgcaaaaa ctcggctata aaggttttcc ggcactaaag ttggcgttga gtgaagcgct
   125461 ggcaagccag ccggaatctc cctccgtgcc cattcataac caaatccgcg gtgatgatcc
   125521 gttacggctg gtcggcgaaa aactgattaa agaaaatact gccgctatgt acgcaacgtt
   125581 aaacgttaat agtgaagaga aactgcatga atgcgtggca atgttgcgct ctgcgcggcg
   125641 gataattctg accggtattg gcgcttcggg tctggtggcg caaaactttg cctggaagct
   125701 gatgaagatt ggcttcaatg ctgccgcagt gcgcgatatg catgcgctac tcgctaccgt
   125761 acaggcgtcg tcccctgacg atctgttatt agccatttcc tacaccggtg tacggcgcga
   125821 gttaaacctg gcggcagatg agatgctgcg agtgggcgga aaagtgctgg cgattaccgg
   125881 ctttactccc aatgccctgc aacagcgtgc ttctcattgc ctgtatacca ttgccgaaga
   125941 acaagcgaca aacagtgctt caatctctgc ttgtcacgcg cagggaatgt taacggattt
   126001 gctgttcatt gcgctgattc agcaggatct ggaactggca ccagaacgta ttcgtcatag
   126061 cgaagcgctg gtgaaaaaac tggtctgagt aaagaatgcg cgtataatgc ccgcccggtt
   126121 tgtgttgttt tgagagtttc cttatggcgc tgttaatcac taaaaaatgc atcaattgtg
   126181 atatgtgtga acccgaatgc ccgaatgagg cgatttcgat gggtgaacat atctacgaga
   126241 ttaacagcga taagtgtacc gaatgcgtag ggcactacga gacaccaacc tgccagaagg
   126301 tgtgtccgat ccccaatact attgtgaaag atccgcaaca tgtcgagacg gaagaacagt
   126361 tgtgggataa atttgtgctg atgcaccacg cggataaaat ttaatattct gctctggaag
   126421 tagagtgtta attattttat agagaaatct taacgctatt atatt
//
LOCUS       DAFGPF010000003       111810 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFGPF010000003 DAFGPF010000000
VERSION     DAFGPF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 111810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 111810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..111810
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.003"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(55..1419)
                     /gene="tdcG"
                     /locus_tag="LSX49_000248"
     CDS             complement(55..1419)
                     /gene="tdcG"
                     /locus_tag="LSX49_000248"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBL7166719.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEELLSKTYYSVGGGFIVEEEHFGLS
                     HDVETPVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(1491..1880)
                     /locus_tag="LSX49_000249"
     CDS             complement(1491..1880)
                     /locus_tag="LSX49_000249"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HBL7166720.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            complement(1894..4188)
                     /gene="tdcE"
                     /locus_tag="LSX49_000250"
     CDS             complement(1894..4188)
                     /gene="tdcE"
                     /locus_tag="LSX49_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HBL7166721.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPLDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIRSSFHAYGREMDSEFEYIFTDLRKTHNQGVFDTYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRRALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEALPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGMDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            complement(4222..5430)
                     /gene="tdcD"
                     /locus_tag="LSX49_000251"
     CDS             complement(4222..5430)
                     /gene="tdcD"
                     /locus_tag="LSX49_000251"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312022.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HBL7166722.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGVEIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHL
                     GKVNAPAEFA"
     gene            complement(5456..6787)
                     /gene="tdcC"
                     /locus_tag="LSX49_000252"
     CDS             complement(5456..6787)
                     /gene="tdcC"
                     /locus_tag="LSX49_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HBL7166723.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            complement(6809..7798)
                     /gene="tdcB"
                     /locus_tag="LSX49_000253"
     CDS             complement(6809..7798)
                     /gene="tdcB"
                     /locus_tag="LSX49_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HBL7166724.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
     gene            complement(7897..8835)
                     /gene="tdcA"
                     /locus_tag="LSX49_000254"
     CDS             complement(7897..8835)
                     /gene="tdcA"
                     /locus_tag="LSX49_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HBL7166725.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTATLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVD"
     gene            9150..9368
                     /gene="tdcR"
                     /locus_tag="LSX49_000255"
                     /pseudo
     CDS             9150..9368
                     /gene="tdcR"
                     /locus_tag="LSX49_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417589.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TdcR"
     gene            complement(9934..10310)
                     /gene="rnpB"
                     /locus_tag="LSX49_000256"
     ncRNA           complement(9934..10310)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LSX49_000256"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(10343..11488)
                     /gene="garK"
                     /locus_tag="LSX49_000257"
     CDS             complement(10343..11488)
                     /gene="garK"
                     /locus_tag="LSX49_000257"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417593.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HBL7166726.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGAERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDSGASRIFGPQKGASEAM
                     IVELDNNLSHYADVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTNDVGVVH
                     QHGIDAVFSVLTSIGTLDEALRGAYDNICRASRNIAATLAIGMRNAG"
     gene            complement(11585..12475)
                     /gene="garR"
                     /locus_tag="LSX49_000258"
     CDS             complement(11585..12475)
                     /gene="garR"
                     /locus_tag="LSX49_000258"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBL7166727.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETAATAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            complement(12505..13275)
                     /gene="garL"
                     /locus_tag="LSX49_000259"
     CDS             complement(12505..13275)
                     /gene="garL"
                     /locus_tag="LSX49_000259"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HBL7166728.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            complement(13291..14625)
                     /gene="garP"
                     /locus_tag="LSX49_000260"
     CDS             complement(13291..14625)
                     /gene="garP"
                     /locus_tag="LSX49_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GarP"
                     /protein_id="HBL7166729.1"
                     /translation="MILDTVDVKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEV
                     AKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGF
                     VDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
                     LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISE
                     NGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIY
                     LVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLL
                     ASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGN
                     VASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
     gene            15000..16571
                     /gene="garD"
                     /locus_tag="LSX49_000261"
     CDS             15000..16571
                     /gene="garD"
                     /locus_tag="LSX49_000261"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HBL7166730.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLQKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            16720..17055
                     /gene="prlF"
                     /locus_tag="LSX49_000262"
     CDS             16720..17055
                     /gene="prlF"
                     /locus_tag="LSX49_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HBL7166731.1"
                     /translation="MPANARSNAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFDIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            17055..17519
                     /gene="yhaV"
                     /locus_tag="LSX49_000263"
     CDS             17055..17519
                     /gene="yhaV"
                     /locus_tag="LSX49_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ribonuclease
                     toxin YhaV"
                     /protein_id="HBL7166732.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVEALKGKDPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH"
     gene            complement(17574..18383)
                     /gene="agaR"
                     /locus_tag="LSX49_000264"
     CDS             complement(17574..18383)
                     /gene="agaR"
                     /locus_tag="LSX49_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HBL7166733.1"
                     /translation="MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            18632..19912
                     /gene="kbaZ"
                     /locus_tag="LSX49_000265"
     CDS             18632..19912
                     /gene="kbaZ"
                     /locus_tag="LSX49_000265"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HBL7166734.1"
                     /translation="MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPL
                     LIEATSNQVDQFGGYTGMTPAGFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDGIVAERAARLAKVAEETCR
                     EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWP
                     RIIALVVQPGVEFDHTNVIDYQPAKATALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLENVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGELQPTPRELIINHIQDILAQYHTACEGQ"
     gene            19935..20408
                     /gene="agaV"
                     /locus_tag="LSX49_000266"
     CDS             19935..20408
                     /gene="agaV"
                     /locus_tag="LSX49_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312038.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HBL7166735.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL"
     gene            20419..21198
                     /locus_tag="LSX49_000267"
     CDS             20419..21198
                     /locus_tag="LSX49_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HBL7166736.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGTFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            21188..22066
                     /locus_tag="LSX49_000268"
     CDS             21188..22066
                     /locus_tag="LSX49_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBL7166737.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AVTVVLGIVGKFCHFL"
     gene            22084..22518
                     /locus_tag="LSX49_000269"
     CDS             22084..22518
                     /locus_tag="LSX49_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL7166738.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            22515..23648
                     /gene="nagA"
                     /locus_tag="LSX49_000270"
     CDS             22515..23648
                     /gene="nagA"
                     /locus_tag="LSX49_000270"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL7166739.1"
                     /translation="MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDALDKLAMHKAREGVGSWLPTTVTAPLNTIHAA
                     LKRIALRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQQT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGHYTLCGEEVQMHGGIVRTAFGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLH
                     PARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF"
     gene            23998..25152
                     /locus_tag="LSX49_000271"
     CDS             23998..25152
                     /locus_tag="LSX49_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HBL7166740.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLQIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAITAESNDVIAAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVTIHPWQA"
     gene            25165..26025
                     /gene="kbaY"
                     /locus_tag="LSX49_000272"
     CDS             25165..26025
                     /gene="kbaY"
                     /locus_tag="LSX49_000272"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HBL7166741.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSRDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
     gene            26192..26668
                     /gene="agaB"
                     /locus_tag="LSX49_000273"
     CDS             26192..26668
                     /gene="agaB"
                     /locus_tag="LSX49_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HBL7166742.1"
                     /translation="MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDD
                     IQQKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGIDL
                     KDVNVGNMHFSEGKKQISSKVYVDDQDLTDLRYIKQRGVNVFIQDVPGDQKEQIPD"
     gene            26707..27510
                     /gene="agaC"
                     /locus_tag="LSX49_000274"
     CDS             26707..27510
                     /gene="agaC"
                     /locus_tag="LSX49_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
                     /protein_id="HBL7166743.1"
                     /translation="MHEITLLQGLSLAALVFVLGIDFWLEALFLFRPIIVCTLTGAIL
                     GDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAKTAIGLGLP
                     FSLLMQYVILFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAVIAFLCT
                     YLAQGAMQALVKAMPAWLTHGFEVAGGILPAVGFGLLLRVMFKAQYIPYLIAGFLFVC
                     YIQVSNLLPVAVLGAGFAVYEFFNAKSRQQAQPQPVASKNEEEDYSNGI"
     gene            27500..28291
                     /gene="agaD"
                     /locus_tag="LSX49_000275"
     CDS             27500..28291
                     /gene="agaD"
                     /locus_tag="LSX49_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708938.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HBL7166744.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKNDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            28292..29059
                     /locus_tag="LSX49_000276"
     CDS             28292..29059
                     /locus_tag="LSX49_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HBL7166745.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIR
                     SKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQPLGLREDQLISFHSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTADRPVTRGITLGLKDILNAREVLLLITGEGK
                     QDATERFLTAKVSTAIPASFLWLHNHFTCVIDEMCRR"
     gene            complement(29109..29972)
                     /gene="rsmI"
                     /locus_tag="LSX49_000277"
     CDS             complement(29109..29972)
                     /gene="rsmI"
                     /locus_tag="LSX49_000277"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBL7166746.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEDDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQGE"
     gene            30037..32073
                     /gene="lpoA"
                     /locus_tag="LSX49_000278"
     CDS             30037..32073
                     /gene="lpoA"
                     /locus_tag="LSX49_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoA"
                     /protein_id="HBL7166747.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELVNQLPQELNDNQRREKT
                     LLAAEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PVPVSAPATSTAAVNAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATT
                     DSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATL
                     YASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMG
                     VDAWSLANHFSQMRQVQGFEINGNTGSLTASPDCVINRKLSWLQYQQGQVVPAS"
     gene            32031..32426
                     /locus_tag="LSX49_000279"
     CDS             32031..32426
                     /locus_tag="LSX49_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBL7166748.1"
                     /translation="MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVN
                     ERGGEIDLIMREGRTTVFIEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            32446..33036
                     /gene="diaA"
                     /locus_tag="LSX49_000280"
     CDS             32446..33036
                     /gene="diaA"
                     /locus_tag="LSX49_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HBL7166749.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV"
     gene            33046..33621
                     /gene="yraP"
                     /locus_tag="LSX49_000281"
     CDS             33046..33621
                     /gene="yraP"
                     /locus_tag="LSX49_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HBL7166750.1"
                     /translation="MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(33734..34774)
                     /locus_tag="LSX49_000282"
     CDS             complement(33734..34774)
                     /locus_tag="LSX49_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL7166751.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWQPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPLLNPAT
                     LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLV"
     gene            complement(34847..35482)
                     /locus_tag="LSX49_000283"
     CDS             complement(34847..35482)
                     /locus_tag="LSX49_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312060.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBL7166752.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNVIAAPTRRPLGDMPGV
                     FNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLFRLLPGNWKSIDARDVARVMLAEAMRPEHEGVTILSSSELRKRAE"
     gene            35610..36128
                     /gene="yhbO"
                     /locus_tag="LSX49_000284"
     CDS             35610..36128
                     /gene="yhbO"
                     /locus_tag="LSX49_000284"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HBL7166753.1"
                     /translation="MSKKIAALITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVVIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIVIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(36108..36551)
                     /locus_tag="LSX49_000285"
     CDS             complement(36108..36551)
                     /locus_tag="LSX49_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HBL7166754.1"
                     /translation="METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFY
                     ILTEEKTRHAQMSGPQAAIAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYN
                     RRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRNSGTEQA"
     gene            36602..36904
                     /gene="yhbQ"
                     /locus_tag="LSX49_000286"
     CDS             36602..36904
                     /gene="yhbQ"
                     /locus_tag="LSX49_000286"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HBL7166755.1"
                     /translation="MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVTEGAGFAELLSSLQTPEIKSD"
     gene            complement(36891..37394)
                     /locus_tag="LSX49_000287"
     CDS             complement(36891..37394)
                     /locus_tag="LSX49_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL7166756.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLHCRWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(37388..37912)
                     /locus_tag="LSX49_000288"
     CDS             complement(37388..37912)
                     /locus_tag="LSX49_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HBL7166757.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            38121..39116
                     /locus_tag="LSX49_000289"
     CDS             38121..39116
                     /locus_tag="LSX49_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL7166758.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQHAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            39125..40003
                     /locus_tag="LSX49_000290"
     CDS             39125..40003
                     /locus_tag="LSX49_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL7166759.1"
                     /translation="MKYSLGPVLWYWPKETLEDFYQQAAASSADVIYLGEAVCSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            40084..41091
                     /locus_tag="LSX49_000291"
     CDS             40084..41091
                     /locus_tag="LSX49_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="luciferase-like monooxygenase"
                     /protein_id="HBL7166760.1"
                     /translation="MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELL
                     G"
     gene            complement(41209..42453)
                     /gene="mtr"
                     /locus_tag="LSX49_000292"
     CDS             complement(41209..42453)
                     /gene="mtr"
                     /locus_tag="LSX49_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HBL7166761.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAVGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMIVLIL
                     VFGVGNALVHILSSFNVLPVYQ"
     gene            complement(42607..44496)
                     /gene="deaD"
                     /locus_tag="LSX49_000293"
     CDS             complement(42607..44496)
                     /gene="deaD"
                     /locus_tag="LSX49_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HBL7166762.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(44489..44569)
                     /gene="yrbN"
                     /locus_tag="LSX49_000294"
     CDS             complement(44489..44569)
                     /gene="yrbN"
                     /locus_tag="LSX49_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HBL7166763.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(44676..45560)
                     /gene="nlpI"
                     /locus_tag="LSX49_000295"
     CDS             complement(44676..45560)
                     /gene="nlpI"
                     /locus_tag="LSX49_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HBL7166764.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(45669..47804)
                     /gene="pnp"
                     /locus_tag="LSX49_000296"
     CDS             complement(45669..47804)
                     /gene="pnp"
                     /locus_tag="LSX49_000296"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBL7166765.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKNAIRRIEEITAEIEVGRV
                     YNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(48051..48320)
                     /gene="rpsO"
                     /locus_tag="LSX49_000297"
     CDS             complement(48051..48320)
                     /gene="rpsO"
                     /locus_tag="LSX49_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBL7166766.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(48469..49413)
                     /gene="truB"
                     /locus_tag="LSX49_000298"
     CDS             complement(48469..49413)
                     /gene="truB"
                     /locus_tag="LSX49_000298"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBL7166767.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(49413..49814)
                     /gene="rbfA"
                     /locus_tag="LSX49_000299"
     CDS             complement(49413..49814)
                     /gene="rbfA"
                     /locus_tag="LSX49_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBL7166768.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(49978..52650)
                     /gene="infB"
                     /locus_tag="LSX49_000300"
     CDS             complement(49978..52650)
                     /gene="infB"
                     /locus_tag="LSX49_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBL7166769.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(52675..54162)
                     /gene="nusA"
                     /locus_tag="LSX49_000301"
     CDS             complement(52675..54162)
                     /gene="nusA"
                     /locus_tag="LSX49_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBL7166770.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA"
     gene            complement(54190..54642)
                     /gene="rimP"
                     /locus_tag="LSX49_000302"
     CDS             complement(54190..54642)
                     /gene="rimP"
                     /locus_tag="LSX49_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBL7166771.1"
                     /translation="MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(54849..54925)
                     /locus_tag="LSX49_000303"
     tRNA            complement(54849..54925)
                     /locus_tag="LSX49_000303"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54889..54891),aa:Met,seq:cat)
     gene            55273..56616
                     /gene="argG"
                     /locus_tag="LSX49_000304"
     CDS             55273..56616
                     /gene="argG"
                     /locus_tag="LSX49_000304"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBL7166772.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ"
     gene            complement(56624..58249)
                     /locus_tag="LSX49_000305"
     CDS             complement(56624..58249)
                     /locus_tag="LSX49_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HBL7166773.1"
                     /translation="MTVFNKFVKSFKSHWLLYLCVIIFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRIPSLPLRLLIAAPFVLLTAADMSISLYSWCIFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKEAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTHSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQKTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENNIFSTAYNNYIINAWMGVTKPEQPQTLEEVIAHYKGDS
                     RVVDANHDVFDYVMLRKEFTEDNQGNPTPEGQG"
     gene            complement(58706..58792)
                     /locus_tag="LSX49_000306"
     tRNA            complement(58706..58792)
                     /locus_tag="LSX49_000306"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58756..58758),aa:Leu,seq:gag)
     gene            complement(58807..59139)
                     /gene="secG"
                     /locus_tag="LSX49_000307"
     CDS             complement(58807..59139)
                     /gene="secG"
                     /locus_tag="LSX49_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBL7166774.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(59367..60704)
                     /gene="glmM"
                     /locus_tag="LSX49_000308"
     CDS             complement(59367..60704)
                     /gene="glmM"
                     /locus_tag="LSX49_000308"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBL7166775.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(60697..61545)
                     /gene="folP"
                     /locus_tag="LSX49_000309"
     CDS             complement(60697..61545)
                     /gene="folP"
                     /locus_tag="LSX49_000309"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBL7166776.1"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLLDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVCVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(61635..63569)
                     /gene="ftsH"
                     /locus_tag="LSX49_000310"
     CDS             complement(61635..63569)
                     /gene="ftsH"
                     /locus_tag="LSX49_000310"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBL7166777.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(63669..64298)
                     /gene="rlmE"
                     /locus_tag="LSX49_000311"
     CDS             complement(63669..64298)
                     /gene="rlmE"
                     /locus_tag="LSX49_000311"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HBL7166778.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            64424..64717
                     /gene="yhbY"
                     /locus_tag="LSX49_000312"
     CDS             64424..64717
                     /gene="yhbY"
                     /locus_tag="LSX49_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBL7166779.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(64873..65349)
                     /gene="greA"
                     /locus_tag="LSX49_000313"
     CDS             complement(64873..65349)
                     /gene="greA"
                     /locus_tag="LSX49_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBL7166780.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            65597..67030
                     /gene="dacB"
                     /locus_tag="LSX49_000314"
     CDS             65597..67030
                     /gene="dacB"
                     /locus_tag="LSX49_000314"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HBL7166781.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVTTLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGIAWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(67071..68243)
                     /gene="cgtA"
                     /locus_tag="LSX49_000315"
     CDS             complement(67071..68243)
                     /gene="cgtA"
                     /locus_tag="LSX49_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HBL7166782.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAK
                     PRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(68259..69224)
                     /locus_tag="LSX49_000316"
     CDS             complement(68259..69224)
                     /locus_tag="LSX49_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBL7166783.1"
                     /translation="MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFL
                     MASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWG
                     VIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLANPGVIAQLSHWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE"
     gene            complement(69351..69608)
                     /gene="rpmA"
                     /locus_tag="LSX49_000317"
     CDS             complement(69351..69608)
                     /gene="rpmA"
                     /locus_tag="LSX49_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBL7166784.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(69629..69940)
                     /gene="rplU"
                     /locus_tag="LSX49_000318"
     CDS             complement(69629..69940)
                     /gene="rplU"
                     /locus_tag="LSX49_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBL7166785.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            70199..71170
                     /gene="ispB"
                     /locus_tag="LSX49_000319"
     CDS             70199..71170
                     /gene="ispB"
                     /locus_tag="LSX49_000319"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HBL7166786.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            71403..71681
                     /gene="sfsB"
                     /locus_tag="LSX49_000320"
     CDS             71403..71681
                     /gene="sfsB"
                     /locus_tag="LSX49_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HBL7166787.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIAKALGTDPWVIWPSRYHDPQTHEFIDRTQLMRSYTKPKK"
     gene            complement(71729..72988)
                     /gene="murA"
                     /locus_tag="LSX49_000321"
     CDS             complement(71729..72988)
                     /gene="murA"
                     /locus_tag="LSX49_000321"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL7166788.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(73043..73297)
                     /gene="ibaG"
                     /locus_tag="LSX49_000322"
     CDS             complement(73043..73297)
                     /gene="ibaG"
                     /locus_tag="LSX49_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HBL7166789.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(73457..73750)
                     /gene="mlaB"
                     /locus_tag="LSX49_000323"
     CDS             complement(73457..73750)
                     /gene="mlaB"
                     /locus_tag="LSX49_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HBL7166790.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEIREEAVKGITSIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(73750..74385)
                     /gene="mlaC"
                     /locus_tag="LSX49_000324"
     CDS             complement(73750..74385)
                     /gene="mlaC"
                     /locus_tag="LSX49_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HBL7166791.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQRDAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(74404..74955)
                     /gene="mlaD"
                     /locus_tag="LSX49_000325"
     CDS             complement(74404..74955)
                     /gene="mlaD"
                     /locus_tag="LSX49_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HBL7166792.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(74960..75742)
                     /gene="mlaE"
                     /locus_tag="LSX49_000326"
     CDS             complement(74960..75742)
                     /gene="mlaE"
                     /locus_tag="LSX49_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HBL7166793.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(75750..76559)
                     /gene="mlaF"
                     /locus_tag="LSX49_000327"
     CDS             complement(75750..76559)
                     /gene="mlaF"
                     /locus_tag="LSX49_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HBL7166794.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            76769..77746
                     /locus_tag="LSX49_000328"
     CDS             76769..77746
                     /locus_tag="LSX49_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBL7166795.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPREGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            77760..78746
                     /gene="kdsD"
                     /locus_tag="LSX49_000329"
     CDS             77760..78746
                     /gene="kdsD"
                     /locus_tag="LSX49_000329"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HBL7166796.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            78767..79333
                     /gene="kdsC"
                     /locus_tag="LSX49_000330"
     CDS             78767..79333
                     /gene="kdsC"
                     /locus_tag="LSX49_000330"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HBL7166797.1"
                     /translation="MSKAGASLATCYGPVSADVMAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            79330..79905
                     /gene="lptC"
                     /locus_tag="LSX49_000331"
     CDS             79330..79905
                     /gene="lptC"
                     /locus_tag="LSX49_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HBL7166798.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            79874..80431
                     /gene="lptA"
                     /locus_tag="LSX49_000332"
     CDS             79874..80431
                     /gene="lptA"
                     /locus_tag="LSX49_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HBL7166799.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            80438..81163
                     /gene="lptB"
                     /locus_tag="LSX49_000333"
     CDS             80438..81163
                     /gene="lptB"
                     /locus_tag="LSX49_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HBL7166800.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            81211..82644
                     /gene="rpoN"
                     /locus_tag="LSX49_000334"
     CDS             81211..82644
                     /gene="rpoN"
                     /locus_tag="LSX49_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBL7166801.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVPLED
                     ILESMGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            82667..82954
                     /gene="hpf"
                     /locus_tag="LSX49_000335"
     CDS             82667..82954
                     /gene="hpf"
                     /locus_tag="LSX49_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HBL7166802.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            83072..83563
                     /gene="ptsN"
                     /locus_tag="LSX49_000336"
     CDS             83072..83563
                     /gene="ptsN"
                     /locus_tag="LSX49_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HBL7166803.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LAPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            83609..84463
                     /gene="rapZ"
                     /locus_tag="LSX49_000337"
     CDS             83609..84463
                     /gene="rapZ"
                     /locus_tag="LSX49_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBL7166804.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            84460..84732
                     /gene="npr"
                     /locus_tag="LSX49_000338"
     CDS             84460..84732
                     /gene="npr"
                     /locus_tag="LSX49_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HBL7166805.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            84945..85577
                     /gene="yrbL"
                     /locus_tag="LSX49_000339"
     CDS             84945..85577
                     /gene="yrbL"
                     /locus_tag="LSX49_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HBL7166806.1"
                     /translation="MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALTSREA"
     gene            complement(85574..86302)
                     /gene="mtgA"
                     /locus_tag="LSX49_000340"
     CDS             complement(85574..86302)
                     /gene="mtgA"
                     /locus_tag="LSX49_000340"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HBL7166807.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAIFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEQA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRS
                     RQAWILRQMYQLGGEPFMQQHQLD"
     gene            complement(86299..86952)
                     /gene="elbB"
                     /locus_tag="LSX49_000341"
     CDS             complement(86299..86952)
                     /gene="elbB"
                     /locus_tag="LSX49_000341"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HBL7166808.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFASLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAILPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
     gene            complement(87182..89518)
                     /gene="arcB"
                     /locus_tag="LSX49_000342"
     CDS             complement(87182..89518)
                     /gene="arcB"
                     /locus_tag="LSX49_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HBL7166809.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFERMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(89614..90543)
                     /locus_tag="LSX49_000343"
     CDS             complement(89614..90543)
                     /locus_tag="LSX49_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562163.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBL7166810.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARERGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALGRPWLPPTA"
     gene            91218..95678
                     /gene="gltB"
                     /locus_tag="LSX49_000344"
     CDS             91218..95678
                     /gene="gltB"
                     /locus_tag="LSX49_000344"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HBL7166811.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEDHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVEQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHPGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDDLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            95691..97109
                     /gene="gltD"
                     /locus_tag="LSX49_000345"
     CDS             95691..97109
                     /gene="gltD"
                     /locus_tag="LSX49_000345"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HBL7166812.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVKAIVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
     gene            complement(97177..97641)
                     /locus_tag="LSX49_000346"
     CDS             complement(97177..97641)
                     /locus_tag="LSX49_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBL7166813.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSAIENEQAIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(97638..98513)
                     /gene="nanK"
                     /locus_tag="LSX49_000347"
     CDS             complement(97638..98513)
                     /gene="nanK"
                     /locus_tag="LSX49_000347"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HBL7166814.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPQALRDA
                     LSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIA
                     INDAQAAAWAEYQALDGDITDMVFITVSTGVGGGVVSGGKLRTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGANAKTIFTRAGQGDEQAQQLIHRSA
                     RTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEIL"
     gene            complement(98510..99199)
                     /locus_tag="LSX49_000348"
     CDS             complement(98510..99199)
                     /locus_tag="LSX49_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL7166815.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            complement(99247..100737)
                     /gene="nanT"
                     /locus_tag="LSX49_000349"
     CDS             complement(99247..100737)
                     /gene="nanT"
                     /locus_tag="LSX49_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HBL7166816.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYDPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGISGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALGSLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS"
     gene            complement(100846..101739)
                     /gene="nanA"
                     /locus_tag="LSX49_000350"
     CDS             complement(100846..101739)
                     /gene="nanA"
                     /locus_tag="LSX49_000350"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBL7166817.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            complement(101861..102652)
                     /gene="nanR"
                     /locus_tag="LSX49_000351"
     CDS             complement(101861..102652)
                     /gene="nanR"
                     /locus_tag="LSX49_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417693.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HBL7166818.1"
                     /translation="MSPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
     gene            complement(102760..103257)
                     /gene="sspB"
                     /locus_tag="LSX49_000352"
     CDS             complement(102760..103257)
                     /gene="sspB"
                     /locus_tag="LSX49_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HBL7166819.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDASIMNDEEASADNETVMSVIDGDKPDHDDETHPDDEPPQPPRGGRPA
                     LRVVK"
     gene            complement(103263..103901)
                     /gene="sspA"
                     /locus_tag="LSX49_000353"
     CDS             complement(103263..103901)
                     /gene="sspA"
                     /locus_tag="LSX49_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HBL7166820.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            complement(104296..104688)
                     /gene="rpsI"
                     /locus_tag="LSX49_000354"
     CDS             complement(104296..104688)
                     /gene="rpsI"
                     /locus_tag="LSX49_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL7166821.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(104704..105132)
                     /gene="rplM"
                     /locus_tag="LSX49_000355"
     CDS             complement(104704..105132)
                     /gene="rplM"
                     /locus_tag="LSX49_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBL7166822.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            complement(105352..106479)
                     /gene="zapE"
                     /locus_tag="LSX49_000356"
     CDS             complement(105352..106479)
                     /gene="zapE"
                     /locus_tag="LSX49_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HBL7166823.1"
                     /translation="MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYKELVNSTP
                     PAPRTSGLMARVGKLWGKREDTKHMPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLNDETRAQMDKLWLALAGAKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYEIYQGERLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            106673..107071
                     /locus_tag="LSX49_000357"
     CDS             106673..107071
                     /locus_tag="LSX49_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HBL7166824.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            107225..108592
                     /gene="degQ"
                     /locus_tag="LSX49_000358"
     CDS             107225..108592
                     /gene="degQ"
                     /locus_tag="LSX49_000358"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HBL7166825.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIIRGNESL
                     YLLMR"
     gene            108682..109749
                     /gene="degS"
                     /locus_tag="LSX49_000359"
     CDS             108682..109749
                     /gene="degS"
                     /locus_tag="LSX49_000359"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HBL7166826.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINPRRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQSGGM
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVNNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(109812..110750)
                     /gene="mdh"
                     /locus_tag="LSX49_000360"
     CDS             complement(109812..110750)
                     /gene="mdh"
                     /locus_tag="LSX49_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HBL7166827.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK"
     gene            111185..111655
                     /gene="argR"
                     /locus_tag="LSX49_000361"
     CDS             111185..111655
                     /gene="argR"
                     /locus_tag="LSX49_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HBL7166828.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKELYEAILELFDQEL"
BASE COUNT        27599 a        29938 c        27730 g        26543 t
ORIGIN      
        1 caataaaaaa gggtgcacat tttgtgcacc caaggatgat agctgacagc aatgtcagcc
       61 gcagaccact ttaatagcca gtcctccgcg tgatgtttcg cggtatttat cgttcatatc
      121 tttgccggtt tcatacatcg tctcgatcac tttatcgagt gaaacacgcg gtgccgaggt
      181 gcggcgcatc gccatccgcg cggcgtttac tgctttcacg gcattaatgg cattacgttc
      241 aatgcacggg atttgtacct gtccggcaac cggatcgcag gtcagcccaa ggttatgctc
      301 catcgcgatt tccgccgcat tgcatacctg cgccggactg ccacccagta gttcagttaa
      361 ccctgccgct gccattgaac aggccacgcc aatctccccc tgacagccga cttccgcgcc
      421 agagatggag gcgttcattt tatacagcgc gccaattgcc cccgctgcca gaaaatagcg
      481 ggcaattgac cgctcgttta ccggacgacg gaacttatcg taataagcca gcactgccgg
      541 aataatgccg cacgcaccgt tagtcggtgc cgttaccacg cgcccgccag ctgcgttttc
      601 ttcactaacc gccagcgcgt acatgttgat ccagtcgatg acattcatcg gatcgttaga
      661 gatgttatcg ctggaaacca gttgacgacg cagcgctacg gcacggcgcg gcacattgag
      721 cggaccaggc agcacgcctt cagtattcat tccacgttca ataccgtcat gcatcacttg
      781 ccagatacgg gcaaaccctg cgtcaatttc cgctttactg cgcagcgcca gctcgttgtg
      841 catcatcagg ccagatatag acaggccgtt gtaatcacac attttcagca gttcacctgc
      901 tgagtggaaa tcgtaaggta cgggtgtttc gacatcgtgc gacaggccga agtgttcttc
      961 ttcgacaata aacccgccgc cgacagagta ataggttttg cttaatagct cttcctgtcc
     1021 cttccaggca gtgatccgca ttccgttctc atggcgaggc aacatttcgg gatggaagat
     1081 aatgttcttt gctacaggaa aatcaacaat atgcgcgcca gaagccaccg gcaaccgccc
     1141 gctgcgcgtc actaactcta taaatgcagg gatctcatca atgacaacat cctgcggact
     1201 gtttcctgcc agtcccatga tgatggcgac atccgtggca tggcctttgc ccgtcagtga
     1261 caacgacccg tacagatcga ccacaatatg gctcgtcgcg gttaataagc cgctactttc
     1321 cagccgatca ataaaacttt ttccggcatt cattggcccc acagtatgcg aactggaggg
     1381 accaatccca attttgaaaa tatcgaatgc actaatcata tccacaccct cggattgccg
     1441 ttcagtgaag tggagcggaa cgaccttgcg accgtcccgc tcacgaggct ttacgcacta
     1501 cgtactgcga tggcttcaat ttccagcttc acatctttcg gcaaacgcgc gacctgcaca
     1561 cagctccggg tcgggtaggt cgcctgatgt tcatcgaaga actgcttata gacttcattg
     1621 atggtggcaa aatcattcag atcggtgatg aacacggtca tcttgatgat atcgcccaca
     1681 ctcagcccgg cagcaaccac gatcgctttg acgttttcga ggcttaaacg cgcctgatct
     1741 tgcacatcag ccgggatctc accggtctgt gggcaaaccg gaatttgccc ggaggtgaag
     1801 accatgctgc ctaaatcaac gccctgaaca taagggccga ttgcgcctgg ggcacgttgc
     1861 gtttcgataa tctttttcat acatcctccg gcgtcagagc gcctgggtaa aggtacgtga
     1921 aataacatcc tgttgctgtt cacgggtcag tgcgttgaag cgcacggcgt agccagagac
     1981 acggattgtc aggttaggat atttttccgg gtgctcgatg gcatccagca gcatttcccg
     2041 attcattacg ttgacgttga ggtgttgacc gccttcgaca tccgcttcgt ggtggaaata
     2101 cccatccagc aggccgacaa ggttggtttt acgtactgga tcttctttgc ccagcgccgc
     2161 agggacgatg gagaaggtgt acgagatccc atctttggcg taggtgaacg gcagtttcgc
     2221 caccgacgtc aatgaggcca cggcaccttt gcgatcacga ccgtgcatcg ggttagcgcc
     2281 cggcgcgaac ggtgttccgg cgcggcgacc gtccggcgtg ttcccggttt tctgaccgta
     2341 caccacgtta gaggtgatag tcagaatcga ttgggtcggc acagcattgc gataggttgg
     2401 caaagcttta attttcttca taaagcgttc aaccagatcg caggcaatgc tgtctacgcg
     2461 ctcgtcgttg ttgccatact gcggatattc gccgtcaatc tcgaaatcca ccgccaggcc
     2521 gttttcatca cggattggtt tcacacgagc atatttgatg gcagacaggg agtccgttgc
     2581 caccgacagg cccgcgatgc cgcacgccat ggtgcgatag acatcacgat catgtagcgc
     2641 catcagcgaa gcttcgtagc tgtacttgtc gtgcatgtag tgaatgatat tcagcgcgct
     2701 gatgtactgt accgccagcc agtccatgaa gtggtcgagg ctatccatca ctttgtcgta
     2761 gtccagcacg tcatccatca acggagccgt tttcgggcca acctgaatct tcagcttctc
     2821 gtccattccg ccgttgattg cgtacagtag cgttttcgcc aggttagcgc gcgcaccgaa
     2881 gaactgcatc tgcttaccaa tcaccattgg gctgacgcaa caggcaatcg cgtaatcgtc
     2941 gctattgaag tcagtacgca tcagatcgtc gttttcatac tgcaaagagg atgtgacgat
     3001 agacacctgc gcggcatatt ttttgaaggc aatcggcaag gcttccgacc acagaatagt
     3061 caggttaggt tccggtgcag gccccatagt gtgcagggtg tgtaaatagc ggaaggagtt
     3121 tttggtcacc agggttcgac cgtccaaccc catcccgccg atcacttccg tcgcccagat
     3181 cgggtcgccg gagaacagcg aatcaaattc cggcgtacgc aagaagcgca ccatacggat
     3241 cttcatgatg aagtggtcga tcagttcctg tgcctgctgc tcattgagta cgcctgcttt
     3301 aaagtcgcgc tcaatgtaga tatcgaggaa cgatgccgtg cgccccagcg acatcgcgcc
     3361 gccattttgc gatttcactg ccgccaggta agcgaagtag agccactgca cggcttcttg
     3421 tgcattctgc gctggacgag agatatcaaa gccatatttc gccgccattt cctgaatctg
     3481 taacagcgca cggcgatgtt ctgccagttc ctcacgcaga cgaatggtgg cttcgagatc
     3541 ttcgcctttt tccagacggg actggagatc ggcaaactgc agttcgcgtt cacgtaccag
     3601 ataactgatg ccgtacagtg ccacacggcg atagtcaccg atgatacgcc cacgaccata
     3661 accatctggt aaaccggtca gtacaccaga tttacggcag cgcagcatat ccggtgagta
     3721 agtatcaaat acgccctgat tatgggtttt acgcagatcg gtaaagatgt attcaaattc
     3781 gctatccatt tcacgaccat acgcgtggaa tgaacttcta atcatattaa tgccgccgaa
     3841 cggatgcagc gcacgcttta atggcgcatc cgtttgcaga cccactattt tttccagcgg
     3901 ctggttaata tatcccgcgt catgagcggt aattgtggtg gcaatattgg tatcgaaatc
     3961 caatggcgcg tgagtcgcat tttcgatacg gatgccttcc atgacttttt cccacaattc
     4021 cgtggtggca ggcgtcgctt cggcgagaaa agattcatcg ccttcataag gtgtatagtt
     4081 atgttgaata aaatcgcgga cattaatttc gtttttccag tccgtacctt taaagccaag
     4141 ccatgcgtcg gcgtacagct tatcgctggt atcaatatct accttcatga aaaataatct
     4201 ctctacaata cttcaactaa attatgcaaa ttctgcgggc gcgttcactt tgcctaaatg
     4261 aatggcatcc aaagcaatca ttttttcttc gttagtcgga attacggcgc aaatgacacg
     4321 cgcattttca ctggaaacaa ttcgctctcc aaaagagtta gagcgattat tcatttctgt
     4381 atcaatttct acgcctaata cagctaaatg ttccatgacc agacgacgaa ttaaacttga
     4441 attctctcct attccgccgg tgaatataat tccatccagg cgatgtaatg aagcagcgtg
     4501 tccggcaata tgacgggcaa ttcggtgaac aaaggtttta attgccagtt gcgcgcgttc
     4561 gtgaccttca tgccaggctt tttccagaac acgtaaatcc gaagaaaggc cggaaatacc
     4621 taataatccc gactctttat tcactacgcg ttccaggtcc cccaggctct ggttggtttg
     4681 gctggcgacc caggacatcg ccccgaagtc gacatcacca ctgcgggtac ccatcatcaa
     4741 gccttccagc ggcgtcattc ccattgaagt gtcaacactc tgaccgttgc gaaccgcgca
     4801 gattgatgcg ccattgccaa gatgcgccac aaccaggccg gagtcatctt ccgccagatt
     4861 cagcagcgaa tgtgcgcgct gggaaacata gcggtgcgac gtgccgtgga aaccataacg
     4921 gcgtacacct aactcttcat aatatttcca cggcaggccg tataaataag cttccggagc
     4981 catcgtctgg tggaaactgg tatcaaatac cgccacctga gttacgcccg ggaataattg
     5041 ctgcgccgat tcaataccac ttaaattggc gtaattatgc aggggtgcca gtggagaaac
     5101 gcgacggata ttatcaatga cttcatcggt aataatggcg gactcggtaa aaatactgcc
     5161 gccgtgagcg atgcggtggc caattaaagc cacactgtca tttaaattcc gtttttccag
     5221 ttcaaatgca attgccttca atgcaccttc gtagctgtgg tgagccagcg gtgctggctc
     5281 tcccccattt acggataaga atgcattttc cgagttaata ccgtcggcaa tacctgacat
     5341 taatacttca cagtcgctgg cattgagtac ggaaaactta atcgaagacg aaccacagtt
     5401 aataaccaaa acaaccggaa attcattcat ctcttttctc atcctgagtt acggattaaa
     5461 acagtttgta tacgatgttc aggatggtca gcagaccaat cacggtaaca aacacgttat
     5521 ccagacgacc acggtatttc gccagagacg gcgctttacg gatggcatac atcggcaaca
     5581 ggcacagcag tgatgcgata atcggtgcgc ccatggcttc aatcaagtcg aggatgttcg
     5641 ggttggcgta ggcaacaacc caggtggagc ccataatgaa aatcatgctg atagtattca
     5701 gtttacccag cgacactttg gttttgtcac ctttataacc gaacttcaga atcaaaccat
     5761 tcagcccttc cagcgtcccc agatagtgac cgaagaaaga tttgaaaata gccacgagtg
     5821 cgatgatgga agcggcatat tccagtgtaa tcgcaaacgt tgttttggta ccggtcatgg
     5881 acgcaaagtg gttagccaga taagaaagca ctggaatatt ctgcgctttc gcttcagcca
     5941 tattcgccgg agacagcgta aacaggcagc taaaggcaaa gaacatcacc actgcaacca
     6001 tcagcatact ggcgcgagag atgatttgtg aacatttacg ctcggtgaag tcgcgaccaa
     6061 aatctttctc gtactcttca cgtttagaaa ccacgaagga agagacgatt ggcgagaagt
     6121 taaaggagaa aaccatgatg gaaatcccca gccagacggt gatcaggata ccgtcatgac
     6181 cagttaacga cagcgaaccg aggtcaacct ggtcgataac tgcagagttc cagtaaggga
     6241 tcagcgaaag agaaatcagc accaggctgg cgataaacgg ccataccaga tagctcatca
     6301 ctttaaccat cagatcctta ccaaaccaga tgacgaaagc catcagcagc aacaggaaca
     6361 gcgccacaaa gccgcgattc agcggtgcaa agccgagctg gttttcccag aacgtcataa
     6421 aggtgttggt aatggtaacg ccataaatcc acaacagtgg gcaaatcgcg aagaagtaca
     6481 ggaacgtgat aaccacgccg ccagttttac caaaatgctc ttccaccgtt tccgtaatgt
     6541 tgccggaagg gttagagcca gaaagacaca gacgcgccag tgcccggtgg caataaaacg
     6601 cgatggggta tgctaatacc aacatcagaa gaatcgggat cagtccgcca aaacctgcgc
     6661 ggatagggaa gaacagcacc ccggcgccga ttgccgtacc aaacaagcct aacgtccatg
     6721 tggtatctga tttacgccag gacgattgtt ttgtctggct ggatacaatg ctatctgaag
     6781 tactcatatc ctatcctcaa cgaattaatt aagcgtcaac gaaaccggtg atttgagaga
     6841 cgcgagaaag atcgatattg ccgccggaaa taatactgac ggtttttctg ttttgaatat
     6901 attggtctaa tttaccgctt aataatgcag cacatgccag agcgcctgcg ccttcggtga
     6961 cgactttatt gcgctgaatt aaggcaatca tactgtttct gatttcgtct tcgctgacca
     7021 gcacgatgtc atcgactaat tcacgaacga tttcgtaagt taaattaccc gggcgggaga
     7081 catcacaacc atccgccagg gtgccggtag ttcggtgcgt agttatttct ccggagtgga
     7141 aagaagccgc catgccgtga acgttttcag actgtacgcc aataacacgg atggtcgggt
     7201 tgatagattt aattgccacc gcaataccag caattaaacc gccgccgcca attggcacaa
     7261 tcacgttatc gacatcatag agatcttcca taatttccag accaatcgtt ccctggccag
     7321 caatcacttt cggatcatcg taaggtggga taaaaatacg gccttccatt tcgacaattt
     7381 cgctcacttt agcaatagtg tcgttgaagt tatcaccatg caaaacgact tctgcggagt
     7441 agtcgcacgt tgccgcgact ttggatttcg gcgcaccttt tggcatcacc actttaccgt
     7501 caatacccag catcgcgcag gagagcgaaa ccccttgcgc atggttgccc gcagagcagg
     7561 ccactactcc tttacgtttt tccgcatcag tcagtgaact taatttatta aatgcgccac
     7621 gaattttaaa tgaaccagta cgctgcatgt tttcgaattt gaggaatatt tcacctttgc
     7681 aacgttcact aaaatagttg gagcgaggca tacctgtttt ataaattcgc ccagccagtc
     7741 gttgttttgc ttcaatgatg tcatcaatag caaccgggag atcgtatgta atatgcatta
     7801 taaaacctct tagcctgaat taaatatgta ggtaaccgta accgacacct gcaaaacaga
     7861 caggtggatt atttatgttt aaattaaaac aaataactaa tcaacttcaa ttaattgcct
     7921 tcgtctacac ccattataag atgaatactc tttggctaat tccaccaaaa ccgatgctgc
     7981 ttttttaata cgataatttt tcgaccatac cgcggcatat tgtgccacag gtaatgtttc
     8041 ttcaaccgga atagtaataa attgattaga accaaaaggt gatgtcatat cacaaggaat
     8101 tacagttaag aaatcagcat tgagaacaag attataaatt gtcacgactg agtcggtttt
     8161 aacgatgttt tcaatactga tgccatttct ttgtaacgta gtaagtagtt cgctgtagta
     8221 ccccatattg gtttgtggca acacccactg ttcgttcttc aacgactcca gcgtggcggt
     8281 gccggtgcat gttcgggact tactggctac cagcacaaac tcggactcga acagcggctc
     8341 aacatgtaaa tcctgaagct tcatttctgc gcttaacgta ccaatcgcaa aatccagtcg
     8401 accgtcgcgg attgccggta agaacgaaga cagttgcgct tcatacatag aaacctgcgc
     8461 tttcgggaac acctctttga acttgttgat catccctgac ataaaagtaa aaccaatcaa
     8521 tgaaggaaaa ccaaatgaga cttccaccac cgcctcagaa gacataccgc ttatctcatt
     8581 aaccatattt ttcatttcac gggtaatgga ttcggaacgg gagagtaaca attgaccggc
     8641 aggtgttaat gttacaccgg tatttttccg caccactaac tccaccccaa aataatcttc
     8701 aatatcgtta atgattttac tgacggccgg ttgagttaac cctaactctt ttgcagccga
     8761 gccgatagaa ccacttctaa taacttcctg aaagactacc aggtgctgcg ttttcggaag
     8821 aagaatagtg ctcataacga cctacgttaa ttacctcatt gacggtatga agtgtatcaa
     8881 aatgaaatga acaggatatg tgcgaccact cacaaattaa ctttcaatac tttccatagc
     8941 atcgttaccc caattaaata cctttaagta tcaacaagtt aaagtatgaa aatcagcata
     9001 aaccctgatt tttgtcaaaa aaaatgacgg ggataaccat attttatggc gataacatca
     9061 ttctttatgt ggttaataca aaaaaggggc tgagactata tttcaagcaa ttaccggata
     9121 attaccaggc aaaatttgag ttaaatttaa tgagtaagtt ctcaaatttt attataaaca
     9181 aaccattttc agcgataaat aatgcggcac gtcacatttt ttaacgctat ttgttggaga
     9241 acaaacattt attttatcaa tattttaaaa tttcgaatac aggtattgat catctcgaac
     9301 aattgattaa cgtcaacgtt ttctcttctg acaggatgtc attttgtgaa tgcaatcgtt
     9361 ttccataaat tcttctccca tcataggcaa cgaagagcat tttgtgttga ggatcacaaa
     9421 acgaataatt gctggtcgcc gcgataaggt cagacgaaga caacaagggg gattctcact
     9481 gtgctttaca tcagcgtagg ccatagaatg ttgcttcgtt gactgtaatg ccgggtaaat
     9541 gagcgttttt tgatagtgcg aaagaaccgt gcaaggagaa taagcatcta ttattgtttg
     9601 tcatgatgac aaggcaggca tcaatgaaag gcttctcaat tgcacatatt cttcaccctt
     9661 caatcccgtc aatgcacgca gtggttaaca atcacaatag aaatattgat tattggacgg
     9721 taaaaattta ggttataacg cccaaattat tcaacgatcg gacaatacct gcgaacttac
     9781 aattaatgag agaaatatac gtataattac gaccttttaa atgcaatata gacttaataa
     9841 cttcttacaa agtctgttat taataccgta gatattcatc ttaccctggg cacacaaagc
     9901 aaaaacccgc cgaagcgggt ttttacgtaa atcaggtgaa actgaccgat aagccgggtt
     9961 ctgtcgtgga cagtcattca tctaggccag caatcgctca ctggctcaag cagcctaccc
    10021 gggttcagta cgggccgtac cttatgaacc cctatttggc cttgctccgg gtggagttta
    10081 ccgtgccacg gactgttacc agccgcgcgg tgcgctctta ccgcaccctt tcacccttac
    10141 ctgatcccgc ttacgcgggc catcggcggt ttgctctctg ttgcactggt cgtgggtttc
    10201 ccccccaggc gttacctggc accctgccct atggagcccg gactttcctc ccctccgccc
    10261 gtctcccccg aagaggacga cgacgaagcg gcgactgtct ggtcagcttc ggcgcgcagt
    10321 atagagggtt tgcgcgccct tgtcaccccg cgttgcgcat tccaatcgcc agtgtcgcgg
    10381 cgatattacg tgaagcacgg cagatattgt cataagctcc gcggagtgct tcgtctaacg
    10441 taccaatgct ggtcagtacg ctgaagaccg catcaatgcc atgctgatgt acaacgccaa
    10501 catcattggt caggctaccc gcaatgccaa tcaccggttt atggtacttc ttcgccacgt
    10561 ttgcgacacc aatcggtacc ttgccgtgaa tactctggct atcaatacgc ccttcaccag
    10621 tgatcaccag cgtacaatcg tgaatatgtt cctccagatt cagcgccgta gtgacgattt
    10681 caataccact tttcagttct gcaccaagaa acgccatcag cgccgcgccc atacctcccg
    10741 cagctcctgc gccggggaca tctttcacat caacatgcag cgctttttta ataacatcgg
    10801 catagtgaga gaggttattg tccagctcga caatcatcgc ctcactggct cccttttgtg
    10861 ggccaaagat gcgcgaagca ccactgtcgc cgactaacgg gttggtgaca tcacaagcga
    10921 cgcggatgac acaatctttt aagcgcggat cgagaccgga aatatcaata tcattcagag
    10981 tattaagact accgccgcca aaaccaattt cattgccgtt ggcatcgcat aatttcgccc
    11041 ccagcgcctg taccatgcct gcgccgccgt cgttggtggc gctgccgcca atgccgataa
    11101 taatgtttgt cgcaccgctc tccagcgcct gcaggattaa ctcaccagta ccgcgtgaag
    11161 tggtcacgag tggatcgcgt ttttccgcag gtaccagttc cagcccactg gccgccgcca
    11221 tttcgataaa cgcggttttg ccatcgccgg agatccccca actggcattc actttctcgc
    11281 ccagcggccc tgtaacccag gcgtgacgtt cagccccctg ggtggctgca atcatcgctt
    11341 ccaccgttcc ttcaccaccg tcggcaaccg gaacagaaac atactgtgca tcaggaaaaa
    11401 tttcccgaaa tcctttttct atcgcctgcg caacctcgct ggcagataaa ctttctttat
    11461 aagagtctgg ggcgattacg attttcatac ctatgcctgt taccacatga cgccggaggg
    11521 cgtttctctt attcggcctg gattccaggc ccggattgca atacgccatc cgggcacgac
    11581 gtcattagcg agtaacttcg actttcgcca gtttttcgta gtagcacgcc agggcgctat
    11641 gatccgccgt tcctaaacca tctgcacgca gtgcctgcat catctccata accgcagcag
    11701 tgagcggcag ttgcgcgccg acgccgtgag aagtatccag cgcattcgcc agatccttaa
    11761 tatgcagatc aatacggaag cccggtttga agttgcggtc catcaccatc ggcgctttgg
    11821 catccagcac ggtactgccc gccagcccac cgcgaattgc ctgatacacc agatccgggt
    11881 taacgcccgc tttggttgcc agcgttaacg cttctgacat cgcggcaata ttcagcgcca
    11941 caatgacctg atttgccagt ttggtgacgt tacctgcacc gatttccccg gtatgcacca
    12001 cggaacccgc catcgctttc atcaaatcat agtatttgtc gaaaatagcc ttgtcgccgc
    12061 ccaccatcac tgacagcgta ccgtcgatgg ctttcggttc accgccgctc accggagcat
    12121 ccagcatatc aatgcctttc gctttcagcg cttcgctgat ttcacggctt gccagcggtg
    12181 cgatagaact catatcgatc aataccgtac ctggcttcgc gccttcaata atgccattct
    12241 cacccagcgc cacctctttc acatgagggg agtttggcag catggttatg atgacgtcgc
    12301 actgttcagc gatcgcttta gccgtagcgg ctgtttctgc accggcagca atcacgtcag
    12361 caatagcttc tgggttacgg tcagcaacca ccagcgagta acctgctttc agaaggtttt
    12421 tactcattgg tttacccata atccccaggc caataaaacc aactttcata gtcatatcaa
    12481 tcatctctct tgttgcggtg gtggttattt tttaaaggta tcagccagtt tctgagtggc
    12541 agagcggaag acgccgagat cgctgccgac ggccacaaac gtcgcgcccc attccagata
    12601 acgacgcgca tcagcctcga ccggtgcgag gatgccgctg ggtttgccgt gcgcgctggc
    12661 acggttaaaa atgtgctgaa ttgctttttg tacatccggg tgcgaggcat tgccgagatg
    12721 gcctaatgcc gcagccagat cgctggggcc gacgaagatg ccgtctacac cttcggtagc
    12781 ggcaatagca tcgacgttat ctacgccctg ctgactttct atctggacca gaatagtgat
    12841 gttcttgttc gactgagcga aataatccgc cacggtgcca aacatattgg cgcggtgaga
    12901 aacggagacg ccgcgaatgc cttccggtgg gtaacgagtt gatgccaccg cctgctctgc
    12961 ttcctctttt gtttctacaa aaggaatcag gaagttatag aaaccgatat ccagaagacg
    13021 cttaataatt accggctcgt tggtcggcac tcgcactact ggcgcgctgg cgctgccttt
    13081 cagggccatt aactgcggaa taaacgtgga gatatcgttt ggcgcatgtt caccatccag
    13141 caccagccag tcaaacccag ccaaaccaag aacttcagtg ctaatcgggt tagagagagc
    13201 tgaccagcaa ccaatttgta cctgtttcgc agccagtgcg gctttgaatt tattcgggaa
    13261 aacatcgtta ttcatcgctt atacctttgc ttatttctgc aattccatac gtttaatgtc
    13321 gccgactacg aagaggtagc agaccatcgc catcagcgct gaacatccca cgaaaaccag
    13381 tgctgcattg aaggagtgca gttcacttac cagatagcca atcaccagtg gagtgacaat
    13441 ggaggcaaca ttgccaaaga cgttaaagac gccgccgcag aggccaacaa tctctttcgg
    13501 cgcggtgtca gaaatcactg gccagcccag cgcaccaaat cctttgccaa agaaagccag
    13561 cgccatcagc atgaccacca gcgtggtgtt gttggtgtag ttacataaga tgatggtgga
    13621 agccagcaac attcccagca caattggtag cttacgtgcc agggtcaggg acaaaccgcg
    13681 tttgatcaga taatccgaga agacacctcc cagcacgccg cccgcaaagc cacacagtgc
    13741 cggaatcgag gcgaccagac ccactttcag aatcgacatg cctttttcct gcaccagata
    13801 aattgggaac caggtgagga agaaccaggt gatggtgttg ataaaatatt gtccgaaaaa
    13861 tacgcccagc atcatgcggt tagagagcaa ttgcttgatg taatgcagtt tgggtccgct
    13921 tgctgccgca ctacccggct ttttgtggtc catatcgacc accgcgccat tttccgagat
    13981 aaacttcagc tcttctgcag acatacgtgg gtgatctgtc gggttatgaa tcaacttgat
    14041 ccacagcgcc gtcaacacaa aaccaatcac ccccataacg gtaaagacat gctcccagcc
    14101 ccaggcgaaa gtcagccagc caagcagcgg cgaaaagagc gccaacgaga aatattgcgc
    14161 cgagttaaag atggcggagg cagtaccacg ttctttcgtc gggaaccagg cggcgacaat
    14221 acgggcgttc gccgggaatg atggcgcttc cgagaacccc agcataaatc gcataaagaa
    14281 catggagatc ccagcccagg ccagcggaaa catatcgaca aagccttgca ggaaggtgaa
    14341 cagcgaccag aaaaagaggc tgtaagtgta aactttcttc gagccaaact tatcaagcag
    14401 ccagccgccg ggaatttgca tcagcaagta ggcccagcca aaagcagaga agatgtaacc
    14461 catcgaaacc gcacttaact gcaactcttt tgccacttcg gtaccagcaa tagacagcgt
    14521 tgcacgatcg gcgtagttaa cggcggtaac aataaaaata atcagtaata ttaaatagcg
    14581 ggtatgcacg cctttctttt ttacgtcaac ggtgtccaga atcattttat ttacctcggg
    14641 tacttatgct gatttttatt attatgggga aggtgttatt tatgagtttt atttatgccg
    14701 ttacgacaat gaactcggga attagtataa gcagcgcgag aataataatc attgtgcaaa
    14761 tgctaattta attagtacta tttaaatatt attttgagca tatgcacata aggttgcgcg
    14821 ctaaagcaca gatttgcgct ttaccttgcc gggaggtact gcaatccctg aaatgattga
    14881 cattgatcac atttctgcat ttaaactcct gacattctta tttcacccaa tgaagttatt
    14941 tatttttaaa tgagaccagg tcctcatttt aatagtccct ggctggagaa tattgcacaa
    15001 tggccaacat cgaaatcaga caagaaacgc caactgcgtt ttatataaaa gttcacgaca
    15061 cagataatgt ggcaattatt gttaatgata atggcctgaa agcaggaacg cgttttccgg
    15121 atgggctgga attaattgaa catattcccc aggggcataa agtcgcattg ctggacattc
    15181 cggctaatgg tgaaattatt cgttatggcg aggtgattgg ttacgccgtg cgcgcaatcc
    15241 cacgcggaag ctggatcgac gaatcaatgg ttgtactacc ggaagcgccg ccgttacata
    15301 cgctgccact ggcaaccaaa gtcccggaac ccttaccgcc gctggaagga tacacctttg
    15361 agggctatcg caatgccgat ggcagcgtgg gcaccaaaaa cctgctcggc atcaccacca
    15421 gcgtccactg tgtggcaggc gtggtggact acgtagtaaa aatcattgaa cgcgatctgc
    15481 taccgaaata cccgaacgtc gatggcgtgg tggggctgaa tcatttgtac ggttgtggcg
    15541 tggcgattaa cgcacccgcg gcagttgtac ctattcgtac cattcacaat atttcgctga
    15601 accctaactt tggcggcgaa gtaatggtga ttggtctggg ttgtgaaaag ttgcagcctg
    15661 aacgcctact gactggaacg gatgatgtgc aagctattcc agtagaaagc gccagcattg
    15721 tcagtttgca ggatgaaaag catgtcggtt ttcagtccat ggtcgaggat attttgcagg
    15781 tagccgaacg ccatctacaa aaactgaatc aacgtcagcg agaaacctgt ccggcttcag
    15841 aactggttgt cggcatgcag tgcggtggca gcgatgcgtt ttctggcgta acggcaaacc
    15901 cggcggttgg gtatgcgtct gatctattgg tgcgctgcgg cgcaacggtg atgttttcag
    15961 aagtcacaga agtgcgtgac gcgatccatc tgctgacacc acgcgcagtg aacgaagagg
    16021 tcggcaaacg gctgctggag gagatggagt ggtacgataa ctatctcaat atgggaaaaa
    16081 ccgaccgcag cgccaaccct tcgccgggca acaagaaagg cggtctggca aacgtggtag
    16141 agaaggcact cggctccatt gctaaatcgg gtaaaagtgc aattgttgaa gtgctgtcgc
    16201 ccggccaacg cccgactaaa cgcggattaa tttacgccgc gacgccagcc agcgattttg
    16261 tctgtggcac gcaacaggtg gcttcgggta tcaccgtgca agtgtttacg accggtcgtg
    16321 gtacgccgta cggccttatg gcggtacccg tcattaaaat ggcgacccgc accgagctgg
    16381 cgaaccgctg gtttgattta atggatatta acgcgggcac tatcgctacc ggcgaagaaa
    16441 ccattgaaga agtgggctgg aagttgttcc actttattct cgacgtcgcc agcgggaaga
    16501 agaaaacttt ctcggatcaa tggggactgc ataaccagct ggcggtgttt aacccggcac
    16561 cggtgacctg atttcttttg gaacgtccct cgcaaaacat ggccttagtg ccatgttttt
    16621 attgtttaaa gtccacacat ccattaataa tgcatttgca ttaccttagt tcaagcttat
    16681 aatttgagca gaaaacaggc tgtaaaagga cagtaaataa tgcccgctaa tgctcgctct
    16741 aacgctgtac tgaccactga atcaaaggtc actatacgcg gacaaacaac tatccccgcg
    16801 ccagtgcgtg aggccttaaa actgaagcca ggcctggaca gcattcatta cgaaattctg
    16861 cctggtgggc aagtatttat gtgccgactg ggagatgaac aggaggatca tactatgaat
    16921 gcatttttgc gttttctgga tgcagatatc cagaacaatc cgcaaaaaac tcgtccattc
    16981 gacattcaac aaggaaagaa acttgtcgct ggcatggacg tcaacattga cgatgagatt
    17041 ggcgacgacg aataatggat tttccacaaa gggttaatgg ttgggcgcta tatgctcatc
    17101 cctgttttca ggaaacctac gatgctttag ttgccgaagt cgaggcatta aagggaaaag
    17161 atcctgaaaa ttatcagaga aaagctgcca caaagttatt ggcggtggtc cataaagtga
    17221 ttgaggagca tatcacggtc aatccatcat caccggcatt ccgtcatggc aagtcgttag
    17281 gctctgggaa aaataaagac tggtcacggg taaaatttgg tgctggtcgc tatcgtctct
    17341 tctttcgtta cagtgaaaaa gagaaagtca tcattctggg atggatgaac gatgaaaaca
    17401 cgctgcgcac ctacggtaaa aaaacagatg cctataccgt attcagtaaa atgttaaaaa
    17461 gaggacatcc tcctgccgac tgggaaagcc tcacccaaga gacagaagaa aaccattgat
    17521 ggtgttcaca atgcccgccg aacgcattgg tgttgaccag cgggcatcct ttctcattcc
    17581 ccgaccagaa tcacttcaac cccagccttt cgcagtcctt ccagactatc cgcaggaatg
    17641 ccttcatcaa caatgatcat gtcgatacgt tgagtatcaa tgatcttatg taaactggaa
    17701 cggttgaact tactggaatc ggtgaccacg atgatccgtt ccgcaacttc gcacatccga
    17761 cggtttaaac gggcttcatc ttcattatgc gtgctgacgc cacgctccag atcgatcgca
    17821 tctacaccaa gaaacagcat atcgaagtgg taattttgca gcgattgctc agcctgatca
    17881 ccgtaaaaag attgcgactg acggcgcaaa tgccccccgg tcatcagcag ctcaacgcct
    17941 tccgcttcca gcaacgcatt agccacgttc ataccgttgg tcatcgcaat tacgtcggtg
    18001 tgcttgcgca tcagacgagc aatctcaaaa gtggtggtcc cggagtcgag gatcacccga
    18061 tgaccaggct gaatcaactc aacggcagct ttcgcaacgc tgcgtttcat cgcggtgttc
    18121 agtgcgcttt tatcttccac tgatggctcg actgacggcg ttgtgctatc gcagatcaac
    18181 gcgccaccat aggcacgcac ggcgatcccc tgcttttcca gaaacgccag atcgttgcgg
    18241 atcgtcacag tagatacgcc atacaatgcc gacagatcgt taacctgcac actcccttgc
    18301 tgtcgcagac gctgaatgat ctgttctcgt cgctcgctgg tgcctgtcac tcgcttctca
    18361 cctgaagcgt cggtattact catagtaagt cctttcgtaa aactttcgtt tcatttcgtt
    18421 ttgcctatta acgcctttct attaagcaaa tgcaagccca ccttacccat tggcgcaagc
    18481 tactctcgtt tcagtggctt tcattatgtt tcttttgtga atcagatcag aaaactatta
    18541 tctttcgttt tatttttatc tcaccatgac gcagtatcaa ctgaaacaaa acgaaagatt
    18601 aatgtcgcag taatctgaac tggagaggaa agtgaaacat ctgacagaaa tggtgagaca
    18661 gcacaaagcg ggcaaaacaa atgggattta tgccgtttgt tccgcacatc cgctggtgct
    18721 ggaagctgca atccgctacg ccagtgcaaa ccaaacgccg ttactgattg aagctacctc
    18781 caatcaggtg gaccagtttg gcggttatac cggaatgacg cccgccggtt ttcgcggctt
    18841 tgtttgtcag ctcgccgact cgttgaattt cccgcaggat gcgctgattc tgggtggcga
    18901 ccatctgggg ccaaaccgct ggcaaaatct gcctgccgct caggcaatgg ccaatgccga
    18961 tgatttgatt aaaagctacg tggcggcagg attcaaaaaa attcaccttg attgcagcat
    19021 gtcctgtcag gacgatccga ttcccttaac cgatggcatc gtggccgaac gcgccgctcg
    19081 tttggcgaaa gtggcggaag aaacctgccg tgaacatttt ggcgaagccg atctggagta
    19141 tgtcattggt accgaagtgc cggtgcctgg cggcgcgcat gaaaccttaa gcgagctggc
    19201 ggtcaccacg ccggatgccg cccgcgccac gctggaagcc catcgtcacg cttttgaaaa
    19261 gcagggtctg aatgccatct ggccacgcat cattgccctg gtggttcaac ccggcgtcga
    19321 attcgatcac accaacgtta ttgattatca gcccgccaaa gcgaccgcct taagccagat
    19381 ggtcgaaaac tacgaaacgc tgattttcga agcgcactct accgattatc aaacgccgca
    19441 atcgctgcgc cagctggtga ttgaccactt tgccattctg aaagttggcc cggcgctgac
    19501 ctttgctctg cgtgaagctc tgttctctct ggcagcgatt gaagaagaac tagtgccagc
    19561 aaaagcctgt tctggtctgc gtcaggtgct ggaaaacgtg atgctcgacc gcccggaata
    19621 ctggcaaagc cactaccacg gtgacggcaa cgcgcgtcgt ctggcgcgtg gttatagcta
    19681 ctcggatcgc gtgcgctatt actggccgga cagccagatt gatgacgctt tcgctcatct
    19741 ggttcgtaat ctggcggatt caccaattcc gctgccgctg atcagtcagt atctgccgct
    19801 gcagtacgtg aaagttcgct ccggcgagct gcagccaacg ccacgggaac tcattatcaa
    19861 ccatattcag gacatcctgg cgcagtacca cacagcctgt gaaggccaat aagcaaaaca
    19921 aagaggaaca cgctatgcca aatattgttt taagtcggat tgatgaacgc ttgattcacg
    19981 gtcaggtcgg cgttcagtgg gtaggatttg cgggggcaaa tctggtgctg gtagccaacg
    20041 atgaggttgc cgaagatccg gtacaacaaa acctgatgga aatggtactg gcagaaggga
    20101 tcgccgtacg tttctggacg ctgcaaaaag tcatcgacaa catccatcgc gccgccgatc
    20161 gacagaaaat cctgctggtt tgtaaaacac cggccgattt cctgacgctg gtgaaaggtg
    20221 gcgttccggt gaatcgcatt aacgttggca atatgcacta cgccaatggc aagcaacaaa
    20281 tcgccaaaac ggtttctgtg gatgcgggtg atatcgcagc atttaacgac ctgaaagccg
    20341 ctggggtgga atgcttcgtt cagggcgtcc cgacagagcc tgctgtggac ctctttaaat
    20401 tactttgagg gattcatcat ggaaatcagt ctgttgcagg catttgcgtt gggcattatc
    20461 gcctttatcg ctggcctgga tatgtttaac ggcttaaccc atatgcaccg cccggtggtt
    20521 ctcggcccgt tggtcgggct ggtacttggc gatctgcata ccggtatttt aaccggcggt
    20581 acgctggaac tggtgtggat ggggctggcc ccgctggcgg gcgcacagcc gcctaacgtg
    20641 attatcggta ctatcgtcgg cacggcgttt gccattacta ctggcgtgaa acccgatgtc
    20701 gcggtcggtg tcgccgtacc tttcgctgtt gcagtacaga tggggattac cttcctgttc
    20761 tcggtgatgt ccggcgtgat gtcccgctgc gaccggatgg cggagaacgc cgatactcgc
    20821 ggcattgaac gcgtgaacta tctggcactg ctggcactcg gcactttcta ttttctctgc
    20881 gctttcctgc ctatctactt cggcgcggaa catgcaaaaa ccatcattga tgtcctgccg
    20941 caacgattaa ttgatggcct cggcgtcgcg ggcggcatca tgccagcaat cggttttgcc
    21001 gtgctgctga aaatcatgat gaaaaacgtc tacatcccct acttcatcct gggctttgtt
    21061 gccgcagcct ggctcaagtt accggtgctg gctattgctg ccgctgcgct ggcgatggcg
    21121 ctgatcgacc tgctgcgtaa atctcctgaa ccgactcaac ctgcggcaca gaaagaggaa
    21181 tttgaagatg gcatctaatc aaaccaccct gccgaacgtc agcgaaaatg aagaaacact
    21241 gctgactggc gtcaatgaaa acgtgtatga agatcagagc attggcgcag agctgacgaa
    21301 aaaagatatc aaccgcgtcg cctggcgctc catgctgtta caagcgtctt tcaactacga
    21361 acgtatgcag gcttccggct ggttgtacgg tctgctgcct gctctgaaaa agatccacac
    21421 taataaacgg gacctggcgc gcgccatgaa ggggcatatg ggtttcttca atacccatcc
    21481 gtttctggtg acgtttgtta tcggcattat ccttgcgatg gagcgttcta agcaggacgt
    21541 taacagtatt cagagcacca aaattgccgt cggtgcgccg ctcggcggga ttggcgatgc
    21601 gatgttctgg ctaacgctac tgccgatttg tggcgggata ggcgcaagcc tcgcgctaca
    21661 aggctctatt cttggcgctg tcgtctttat tgtgctgttc aacgtggtgc acctggggct
    21721 gcgttttggt ctggcgcatt atgcttaccg catgggcgtg gcggctattc cactcattaa
    21781 agcaaatacc aaaaaagtcg gccatgcggc gtctatcgtt gggatgacgg tgatcggcgc
    21841 gctggtggca acctatgttc gtttaagcac cacgctggaa atcacggcgg gcgacgcagt
    21901 ggttaagtta caggctgatg ttatcgacaa actgatgcct gccttcttac cgctggtcta
    21961 caccctgacc atgttctggc tggtacgccg cggctggagt ccgctgcgcc tgattgcagt
    22021 gacagtggtt ctcggcatcg tcggtaaatt ctgccatttc ctttaaatac aatgaggtat
    22081 tagatgttaa gtattatttt gacagggcat ggcggatttg ccagcggcat ggaaaaagca
    22141 atgaagcaaa tcctcggcga gcaatcgcag tttatcgcca tcgattttcc agaaacctca
    22201 agcaccgcgc tgcttacatc gcagcttgaa gaggccatcg cccaactgga ttgtgaagac
    22261 ggcattgttt ttctgacgga tttgctgggc ggcacgccgt ttcgcgtagc ttcaacgctg
    22321 gcgatgcaaa aaccgggctg tgaagtgatc accggcacaa atttgcaact attactggaa
    22381 atggtgctgg aacgcgaagg gttaagcggt gaagagttcc gtgtgcaggc gctggagtgt
    22441 ggacaccgtg ggctaaccag tctggtggac gaacttggtc gctgccatga ggaatgtccg
    22501 gtcgaggaag gaatatgaca cacgttctgc gcgccagaag gctgctgact gaagagggat
    22561 ggctcgatga ccatcagttg cgtattgctg acggtgtaat cgcagcaatc gaaccgattc
    22621 cagtgggcgt gactgaacgc gatgcggaac tgctctgccc cgcttacatc gacacccatg
    22681 tacacggtgg tgcgggcgtt gatgtaatgg atgacgcgcc ggatgcgctc gacaagctgg
    22741 caatgcacaa ggcacgcgaa ggtgtcggca gttggttacc gaccaccgta accgcgccgc
    22801 ttaataccat tcatgcggcg ctgaaacgta ttgctctacg ctgccagcgc ggtgggcctg
    22861 gtgcgcaagt gctggggagt tatctcgaag gaccgtactt cacgccgcag aataaaggcg
    22921 cacatccgcc ggagctgttt cgcgagctgg aaattgccga gctggatcaa ttgattgccg
    22981 tttctcagca gaccttacgc gtggtagcgc tggcaccaga aaaagaaggg gcattgcagg
    23041 ccatccgcca tcttaaacag caaaacgtac gggtgatgct ggggcatagc gcggcgacct
    23101 ggcaacaaac ccgtgccgcg tttgatgctg gtgccgacgg cctggtgcat tgctataacg
    23161 ggatgacagg tttacatcac cgcgaaccgg gaatggttgg cgcgggatta acggacaagc
    23221 gcgcctggct ggaactgata gccgatggtc atcatgtaca tccggcggca atgtcgctct
    23281 gttgttgctg tgcgaaagag aggatcgtac tgatcaccga cgcgatgcag gcagccggga
    23341 tgccggatgg tcactatacg ttatgtggtg aagaagtgca gatgcacggt ggcattgtcc
    23401 gtaccgcgtt cggtgggctg gcgggcagta cgctgtctgt cgatgcggca gtgcgcaaca
    23461 tggtcgagtt gacgggcgta acgcctgcgg aagccatcca tatggcgtcg ctgcatccgg
    23521 cgcgaatgct gggtgttgat ggtgttctgg gatcgcttaa accgggcaaa cgcgccagcg
    23581 tcgttgcgct ggatagcggg ctgcatgtgc aacaaatctg gattcagggt caattagctt
    23641 cgttttgatg gtttgctcct ttattaggcc ttcacttccc ccgtaaggcc tttctttttc
    23701 tttctttttg atctgtgcag cggtgtcgga tgcgacgcta atgcgcctta tccgacctac
    23761 ggttggtgac cgtaaggccg gataaagtat ttacgccgca tccagcaatc ccttttactt
    23821 cccttgtctt ttctttcaac gatcacagat ttcgttttat ttcctttttc tccattgaac
    23881 tttcagtttc ttttctatag attttaacca acgaaagaaa tcaccaagtg aaatgaaacg
    23941 aaaggcaagc gaaagcgaca acgccgacgt caagttcatc agactaagga ttgagttatg
    24001 ccagaaaatt acacccctgc tgctgccgca accggtacat ggactgaaga agagatccgc
    24061 catcagcctc gcgcatggat ccgttcactc accaacattg acgcgctacg ttccgcgctc
    24121 aataacttcc ttgaaccgtt actgcgcaaa gagaatctgc aaatcatcct gaccggagcc
    24181 ggaacatcgg catttatcgg tgacatcatc gcgccgtggc tcgccagcca taccggtaaa
    24241 aacttcagcg ccgtaccaac caccgatctg gtcaccaatc caatggacta cctgaaccca
    24301 gctcatccgc tactgttgat ctccttcggt cgctccggca acagcccgga aagcgtcgcc
    24361 gccgtggaac tggcaaatca atttgtacca gaatgctatc acctgccgat cacctgcaac
    24421 gaagcgggcg ctctttacca aaacgcgatc aacagcgaca acgcgtttgc cctgctgatg
    24481 cccgcagaaa cgcacgatcg cggctttgcg atgaccagca gcattaccac catgatggcc
    24541 agctgcctcg cggttttcgc acctgagacg atcaacagcc aaaccttccg cgacgtggcg
    24601 gatcgttgcc aggcgatcct gacctcactg ggcgatttca gcgaaggtgt gtttggttac
    24661 gcaccgtgga aacggatcgt ttatctcggc agcggtggct tacagggcgc agcacgcgag
    24721 tcggcgctga aagtgctgga actgacagcg ggtaaactgg cggccttcta tgattccccg
    24781 accggattcc gtcatggccc gaaatcgctg gtcgatgacg aaacgctggt agtggtgttt
    24841 gtctccagtc acccttacac ccgtcagtac gatcttgacc tgctggcaga actccgccgt
    24901 gacaaccagg caatgcgcgt gatcgccatc accgctgaaa gcaacgacgt tatcgccgct
    24961 ggcccgcata tcatcctgcc gccgtcccgt cactttatcg acgttgaaca agcattttgc
    25021 ttcctgatgt acgcccagac gtttgcactg atgcagtcgc tgcacatggg caatacgccg
    25081 gataccccat cagccagtgg caccgtaaac cgcgtggtgc aaggcgtaac tattcatccg
    25141 tggcaggcat aagaggatcg cattatgagc attatctcca ccaaatatct gttacaggac
    25201 gcccaggcca atggctacgc ggtgcctgcc tttaacatcc ataacgccga gacgatccag
    25261 gcgatcctcg aagtgtgcag tgaaatgcga tcgccggtga tcctcgccgg gacaccaggt
    25321 acctttaagc atatcgcgct ggaagagatc tacgccctgt gtagcgccta ttccacgacc
    25381 tataacatgc cgctggcact gcatctcgac caccacgaat cgctggatga tattcgccgt
    25441 aaagtccacg caggcgtgcg cagcgcgatg atcgacggca gccacttccc gtttgccgag
    25501 aacgtgaagc tggtgaaatc ggttgtcgac ttctgccact cccgggattg cagcgtggaa
    25561 gcagaactgg gccgcctcgg cggtgttgaa gatgacatga gcgttgacgc cgaaagtgca
    25621 ttcctgaccg atccacaaga agctaaacgc tttgtcgaac tgactggcgt cgacagcctg
    25681 gcggtagcga ttggtacggc gcacggctta tacagcaaaa cgccgaagat tgatttccag
    25741 cggctggcgg aaattcgtga agtggtggat gttcctctgg tgctgcatgg tgccagcgat
    25801 gtcccggatg aatttgtccg tcgcactatt gaactcggtg taacaaaagt gaacgttgcc
    25861 acagaattaa aaatagcctt cgctggcgcg gttaaagcct ggtttgcgga aaatccgcag
    25921 ggtaatgatc ctcgttatta tatgcgcgtc ggaatggatg cgatgaaaga agtggtcaga
    25981 aataaaatta atgtctgtgg ttcagcgaat cgaatttcag cataatcatt aattttatac
    26041 gttttttcag aatgcactgc ccgattaata tcgggtagta ccttaatggc aaaggagata
    26101 accaaacatt aataaataca tcagtacaat atcgcaacaa taatatattt aaaaatatta
    26161 tattattcaa ctttatggtg aggattacac aatgagcagt ccaaatattc tcttaacccg
    26221 tattgataac cgtctggttc acggtcaggt tggcgtgacc tggacatcca ccatcggtgc
    26281 gaatctgttg gtagtcgtgg atgatgttgt cgctaacgat gatattcaac agaaattaat
    26341 gggtattacc gcagaaacct acggctttgg cattcgtttc tttactatcg aaaaaaccat
    26401 taacgtcatc ggcaaagctg caccacatca gaagatcttc ctgatttgcc gtacgccaca
    26461 aacggtacgt aaattggtag aaggtggtat tgacctgaaa gatgtcaacg tcggcaatat
    26521 gcatttctcg gaagggaaaa agcaaatcag cagtaaagtt tatgtcgatg accaggatct
    26581 cacggactta cgttatatta aacaacgtgg cgtgaatgtt ttcattcagg acgttcctgg
    26641 cgatcaaaaa gaacaaatcc ctgactaaat ctgaaatcgc cttaatattg gtttgaggta
    26701 ataaaaatgc atgaaataac cctactccag ggattatccc tggcggcgtt agttttcgtt
    26761 ctggggattg atttttggct ggaagcctta tttttattcc gcccgataat cgtttgtacc
    26821 cttacaggtg ctattctcgg tgatattcag actggcttaa ttaccggagg cctgacagag
    26881 ttggctttcg ccggattaac ccctgcaggt ggtgttcagc cgcccaaccc tattatggcg
    26941 ggtctgatga ccaccgtcat tgcatggtct acgggcgttg atgccaaaac ggcaattggt
    27001 cttggcctgc cgtttagttt gttaatgcag tacgtcattc tgttcttcta ttccgctttc
    27061 tcattattta tgaccaaagc cgataaatgc gcgaaagagg cggatacggc agcgttttcc
    27121 cgacttaact ggacaacgat gctcatcgtc gcttcagcgt atgcggtgat tgctttcctc
    27181 tgtacttacc tggcacaagg ggcgatgcag gcgctggtga aagcgatgcc cgcctggctg
    27241 acccacggct ttgaagtggc tggcggtatt ctgcctgccg ttggttttgg cttgctgctg
    27301 cgcgtgatgt tcaaagcgca atatatccct tacctgatcg ccggtttcct gtttgtttgc
    27361 tacatccagg tcagcaacct gttgccggtt gccgtgctgg gcgcaggctt tgcggtgtat
    27421 gagtttttca atgcgaaatc ccggcagcaa gcgcaaccgc agcccgttgc cagtaaaaat
    27481 gaagaagagg actacagcaa tgggatctga aatcagtaaa aaagatatca cccgtctggg
    27541 ctttcgttcg tcactgctac aagcaagctt taactacgaa aggatgcagg cgggcggttt
    27601 tacctgggcg atgttgccga tcctgaaaaa gatttataag aacgacaaac cgggcctaag
    27661 cgcggcgatg aaagataacc tcgaatttat taatacccac cctaatctgg tcggatttct
    27721 gatggggtta ttaatttcga tggaagaaaa aggagaaaac cgcgacacca ttaaaggcct
    27781 caaagtggca ctgtttggcc caatcgccgg gattggcgat gcgattttct ggtttacttt
    27841 gttgccgatt atggcgggga tttgctcatc gtttgccagt caggggaacc tgttgggacc
    27901 gattttgttt ttcgccgttt acctgcttat ctttttcctg cgcgtcggct ggacccacgt
    27961 cggttattca gtcggcgtga aggctattga taaagtgcga gagaactcgc agatgattgc
    28021 ccgttcggca accatcctcg ggatcacagt aatcggcggg ctgatcgctt cgtatgtgca
    28081 tattaacgtg gtgacatcgt ttgccatcga cagtacccac agcgtcgcgc tgcagcagga
    28141 tttcttcgat aaagtcttcc cgaatatttt accgatggcc tacaccctgc tgatgtatta
    28201 cttcctgcgg gtgaaaaaag cgcatccggt gctgttaatc ggcgtgacgt ttgttctttc
    28261 tattgtttgt tctgcattcg gcattttgta aatggaacga ggcaccgcgt ctggcggtgc
    28321 ctctttactt aaggaatttc atcctgtgca aacccttcaa caagttgaaa actatacggc
    28381 gttaagtgaa cgtgccagcg aatatttatt ggccgtgatc cgtagcaaac cggatgccgt
    28441 gatttgcctg gcgaccggag ccacgccatt actgacgtat cattatttgg tagaaaaaat
    28501 ccaccagcag caggttgatg tcagccagct caccttcgtg aagctcgacg aatgggtgga
    28561 tctgccatta acgatgcctg gtacctgcga aactttcctt caacagcata tcgtgcagcc
    28621 gctggggcta cgtgaagacc agctcatcag ctttcactcc gaagagataa atgagacaga
    28681 gtgcgaacgg gtaacgaacc tgattgcgcg caaaggcggt ctggacttat gcgttctcgg
    28741 attggggaaa aacggtcatc ttgggctgaa cgaaccggga gaaagcctgc aaccggcctg
    28801 ccatatcagt caacttgatg ccagaacaca gcaacatgag atgttaaaaa ccgctgaccg
    28861 tcccgtgact cgtgggatca ccttaggcct gaaggatatt ctcaatgccc gcgaagtttt
    28921 gttactgata actggcgaag gaaaacagga tgcgacagaa cgttttctca cggctaaagt
    28981 ctccaccgct atcccggctt catttttatg gctgcataac catttcacat gcgtgattga
    29041 tgaaatgtgt cgtcgttaac tcgcctggta caggcgttgc agcgctattc ctgctgcgac
    29101 gcctgtaatc actctccctg ctgctccagc gcatacttat acagcgcatt tttcttcacg
    29161 ccgtgaattt ctgcggccag cgccgccgct tttttcagcg gcagttctgc ctgtaacagc
    29221 gccagcgtgc gcagggcatc agcaggcagg tcatcttcct gcgctttatg gccttcgaca
    29281 atcagcacca tttcgccttt gcgacggttt tcatcttctt ttacccacgc cagcagctcg
    29341 ccaacgggcg cgccgtgaat ggtttcccag gttttggtta gctcacgcgc cagaaccacg
    29401 taacgggatt cgcctaatac cgcaacaata tcttccaggc tatctaacag acggtgggta
    29461 gattcataaa aaatcagcgt gcgcggctcc gcttcaatag cttttagcgc atcacggcgg
    29521 ccttttgatt tggcaggtaa aaagccttca taacaaaaac gatcggatgg taaacccgcg
    29581 gcgcttaacg cagtgatagc agcacacggc cctggtagcg gcaccacgcg aatccccgct
    29641 tcacgacagg tacgcaccag atggtagcca ggatcgttaa ttagcggcgt tccggcatcg
    29701 gaaaccagcg caatgttttg cccctcttgc agcttcgcca gcagcgtttc ggctttttgt
    29761 tgttcgttat gatcgtgcag cgcaaacaac cgggcattaa tcccaaaatg ttgcagcaat
    29821 aaaccggtgt gacgcgtatc ctcggcggca atcagatcaa cggcctgtaa tacctctaat
    29881 gcacgctggg tgatatccgc cagattgccg attggcgtcg gtacaatgta aagctgcccc
    29941 tgagaattat ccgccgattg gtgttgtttc attgtgtcgt ccgtattgcc gatttaatat
    30001 tgagcattgc gtaaaaaaaa tatcactgga tacattatgg taccctcaac attttctcgt
    30061 ttgaaagccg cgcgttgtct gcctgttgtt ttggcagccc tgattttcgc cggttgtggc
    30121 acccatactc ccgatcagtc cactgcttat atgcagggca cggcgcaggc tgattctgct
    30181 ttttacctgc aacagatgca gcaaagttct gatgatacca ggatcaactg gcaattactc
    30241 gccattcgtg cactggtgaa agaaggtaaa accgggcagg cggttgagtt ggttaaccaa
    30301 ctaccgcaag aactgaatga taatcagcgt cgcgagaaaa cactgctggc ggcagagatt
    30361 aaactggcgc agaaagattt tgctggcgcg caaaacttgc tggcgaaaat cacacctgcc
    30421 gatttagaac aaaaccagca agcccgttac tggcaggcaa aaatcgatgc cagccagggg
    30481 cgtccttcca ttgatttact gcgcgcgtta attgctcagg aaccgctgct cggtgcgaaa
    30541 gaaaagcagc agaatattga cgccacatgg caggcgctct cctccatgac tcaggagcag
    30601 gcgaatacgc tggtgatcaa cgccgacgaa aatattctgc aaggctggct ggatttgcag
    30661 cgcgtctggt ttgataaccg taacgatcct gacatgatga aagctgggat cgccgactgg
    30721 cagaaacgtt atccgaacaa cccgggcgcg aaaatgctgc caacgcagtt ggttaacgta
    30781 aaagcgttta aaccagcatc gaccaacaaa atcgccctgc tgttgccgct gaatggccag
    30841 gcagcggtat ttggtcgcac tattcagcaa ggctttgaag cggcgaaaaa tatcggcact
    30901 cagccagtgg cggcccaggt agctgccgca cctgccgcag acgtagcaga acaacctcag
    30961 ccgcaaaccg tggatggcgt tgccagcccg gcacaagctt cggttagcga tctgaccggt
    31021 gaacagcctg cggcccagcc ggtacctgta agcgccccgg cgacaagcac cgcagcggta
    31081 aacgcacccg caaatccatc cgcagagctg aaaatctacg atacctcatc acaaccactt
    31141 agccagatct taagccaggt tcagcaggat ggtgcgagta ttgtggtcgg tccgttgctg
    31201 aaaaataacg ttgaagagtt gctgaagagc aacaccccgc tgaacgtgct ggcactgaac
    31261 cagccggaga atatcgaaaa ccgcgtcaat atttgttact tcgcgctttc gccagaagac
    31321 gaagcgcgcg atgcagcgcg tcatattcgt gaccagggta aacaagcgcc gctggtgctg
    31381 atcccgcgca gttcattggg cgatcgcgta gccaatgcgt ttgcgcaaga gtggcagaaa
    31441 ctgggtggcg gcaccgttct gcaacaaaaa tttggttcca ccagcgaatt acgcgcgggt
    31501 gttaacggcg gttctggtat tgctttaacg ggtagcccga ttactcccag agcgacaacc
    31561 gactccggca tgacgaccaa caatccaacg ctgcaaacca cgccaaccga tgaccagttc
    31621 accaataatg gcggtcgtgt cgatgcggtg tacattgtgg caacgccggg tgaaatcgct
    31681 tttatcaaac cgatgatcgc catgcgtaac ggtagccaga gcggtgcaac gctgtacgcc
    31741 agttcccgca gtgcgcaagg gaccgctggc ccggatttcc gcctggagat ggaaggcttg
    31801 cagtacagcg aaatcccgat gctggcaggc ggtaatctgc cgttaatgca gcaggcgctc
    31861 agcgcggtga acaacgatta ttcgctggct cgcatgtatg cgatgggtgt cgatgcctgg
    31921 tcgttggcaa atcatttctc acaaatgcgc caggttcagg gttttgaaat caacggtaat
    31981 accggaagcc tgacggcaag cccggattgc gtgattaaca ggaagttatc atggctacag
    32041 taccaacaag gtcaggtagt ccccgccagt taaccaccaa acagaccggc gatgcgtggg
    32101 aagcacaagc gcgtcgctgg ctggaaggca aaggactacg gtttatcgcc gctaacgtga
    32161 acgagcgtgg cggcgagatc gatctgataa tgcgtgaagg ccggaccacc gtttttatcg
    32221 aggtgcgtta ccgccgctct gcgctttatg gcggcgcggc agccagtgtg acccgcagca
    32281 aacaacacaa attattacag actgcccgtt tgtggctcgc gcgtcataat gggagttttg
    32341 atactgtgga ttgccggttc gatgtggtag ccttcaccgg gaatgaggtt gagtggatta
    32401 aggatgcctt taatgaccac tcataattaa ggtttaagga ttagcgtgca agaaagaatt
    32461 aaagcttgct tcactgaaag cattcaaact caaattgcgg cggcagaggc gcttccggat
    32521 gccatctccc gtgcagccat gacgctggtt cagtctctgc tcaatggcaa caaaatcctc
    32581 tgttgtggta atggaacttc cgctgccaat gcacagcatt ttgctgccag catgatcaac
    32641 cgtttcgaaa cggagcggcc cagcttacct gccattgcac taaatactga taatgttgtc
    32701 ttaacggcaa ttgccaacga tcgcttacat gatgaagtgt atgcaaaaca ggtgcgggcg
    32761 ctgggtcatg cgggagatgt attgttagcc atttccaccc gtggcaacag ccgcgatatt
    32821 gtaaaagcgg tagaagctgc cgttacgcgt gatatgacca ttgtggcatt aaccggctat
    32881 gacggcggtg aacttgcagg tttgttaggg ccacaggatg tggagatccg cattccttcg
    32941 catcgtagtg ctcgcattca ggaaatgcat atgctgacgg taaattgcct gtgcgatctg
    33001 atcgataaca cgcttttccc tcaccaggat gtttaaggag aatacatgaa ggcattatcg
    33061 ccaatcgcag tccttatttc cgcgctgctg ttgcaaggtt gtgttgccgc tgccgtagtg
    33121 ggtactgctg ctgtgggtac caaagccgca actgacccac gcagtgtcgg cacccaggta
    33181 gacgatggta ccttggaagt gcgcgtgaac agcgcattgt cgaaagacga acaaattaag
    33241 aaagaagcgc gcattaatgt aacggcctat cagggcaaag tgctgctggt tgggcagtca
    33301 ccaaacgctg aactttcggc tcgcgccaaa cagattgcta tgggcgtaga cggtgccaac
    33361 gaagtgtata acgagattcg tcagggccag ccgattggtc tgggcgaagc gtctaacgat
    33421 acgtggatca ccaccaaagt acgttcgcag ctgttaacca gcgacctggt gaaatcgtcc
    33481 aacgtgaaag tgaccaccga aaacggtgaa gtgttcctga tggggctggt gactgaacgt
    33541 gaagcgaaag cggcggcaga tattgccagc cgggtaagcg gcgtgaagcg ggtaactacg
    33601 gcgtttacgt ttattaaata gcagcccttg taatgcctga tgcgacgctt gcagcgtctt
    33661 atcaggccta caacgatgca aaccgtaggt cggataaggc gtttacgccg catccgacat
    33721 gttttccctc aaatcaaact aacagcgcca gcccgccgac aatcacacca gacactgcca
    33781 ccatcgcccc cgtcagccat aaggctttcg ccgggaacgc tttgcgcagc ataatcagtg
    33841 acggcaaact caccgccggg agcgtcatca acaatgccag cgccggagca gttcccatac
    33901 ctgccagcat catcgtttgt acaatcggaa tttctgctgc cgtgggaatg acaaacaagc
    33961 atcctgccac cgccatcgcc accacccaca tcaggctgtt atcgacagca ccatcggcat
    34021 gggggaataa ccagacgcga gcggcaccca acaccagtac tgcaaggatg taaaccggga
    34081 tcgtactcca gaaaagcgtc catagcgccc tgccccagcg gctaaaaaat cctccctgtg
    34141 cttccggtat atcaatttcg accggtgcct gcgtttgcgg tgtttcacgc acccattttt
    34201 gcaccagcgt cgcaatcagc aacaccatca ccagccccgc caccagacga atcgccgcaa
    34261 aaccccagcc gaggacgaac cccataaaca ccagcgtcgc cgggtttaac aacggattcc
    34321 ccatccagaa tgccagcgca ccgcccatcg acacctgttg gcgacgcatt cccgccgcga
    34381 ccggagccgc acagcaggta cacatcatac ccggcagcga aaacagcgtt cccagcagcg
    34441 tgccgcgaaa gcgcgattgc ccaagcgtac gcaacaacca gtcacgcggg atcagtacct
    34501 gaatcaacga accgaggatc acccccagca ccgccgcttt ccataccgcg aggaaataga
    34561 tcatcgcgta atccaacgcc gcctgccacg gattagcatc cgcctgcgca aggatagatt
    34621 taccgatact gtgggtttcg gcagcagtaa acgctttgcc gtagtaaggt tgccatttca
    34681 cataccagag accggcaatg acaacgagaa agaaaagcgc gggtttccac cactgaatgg
    34741 gcgttgccgc ctgagatgaa gactgaccag tcatagcatt ccccaggaat aagttatgat
    34801 aattgagcgc gtgaatatta cgctcactat caattcttgg gaataattat tcagctcttt
    34861 tgcgtaattc tgaagagctt aaaatcgtca caccttcatg ctcaggccgc atcgcctctg
    34921 ccagcatgac ccgcgccacg tctctcgcat caatggattt ccagttaccg ggtaacaaac
    34981 ggaacagcgg cgcaaaaagc gtttcgttca tccgctgttt gctacgatca cccagtaaca
    35041 tcgacgggcg agcaatggtc aatttcggcc agttctgggc gattaatgct tcttccatct
    35101 cccctttgac gcggttatag aaaaacggcg agtgggcatt agcacccata gcactgacca
    35161 ccagcatatg ctgcgcaccg agccgccgcc cggttaatgc ggtatccacc accaacgtgt
    35221 aatcggcatg aataaacgcc tctttgctcc ccgcttctcg ccgcgtggtg ccgagacaac
    35281 aaaacacaat gtcgatggga tcggtgacct gcgccagcgc gtcagtcagt tgcggatcat
    35341 ggggattaaa caccccgggc atatcgccca acggacgtcg cgtcggcgca gcaatgacgt
    35401 taactttcgg ttcattaatc aacatccgca gcaggtgacc gcccaccagc cccgttgcgc
    35461 ctgtaatcag tacctgactc atcttcgctc ctttacagaa ttgtctgcct tgcgctcccc
    35521 agctcatgca ccaggcttaa tagaccatga ggtaattatc cccgattgtg gaaaattcgc
    35581 ctcatccaat gcaacaacgc ggaggaagca tgagtaagaa aatcgccgct ttaatcactg
    35641 atgaatttga ggattcagaa ttcacttcac ccgcagacga gttccgtaaa gccggacacg
    35701 aagtgattac cattgaaaaa caagcgggta aaacggtgaa aggcaaaaaa ggagaagcca
    35761 gcgtggtcat cgataaatcc atcgatgaag tgacgcccgc agagttcgat gccctgctgc
    35821 taccgggcgg tcattcacca gattatctgc gtggcgacaa ccgttttgtc accttcactc
    35881 gcgattttgt gaacagcggc aaacctgttt tcgccatctg tcacggtccc cagttgctga
    35941 tcagcgccga tgtgatccgt ggtcgtaagc tgaccgccgt taaaccgatc gtgattgatg
    36001 ttaaaaacgc gggcgcggaa ttttacgatc aggaagtggt ggtcgataaa gatcagctgg
    36061 ttaccagccg gacaccggac gatctgccag cgtttaaccg cgaggcgtta cgcctgctcg
    36121 gtgcctgagt tacgtagcca aatcattttt ttaccaaagc ccagcgtgtt gtcggtgaat
    36181 ttgatttcat cgagccggat ttcccatacc ggggccgaca gcattctggc aaccggaaag
    36241 cgacgattgt acgccttgcg tgcgaggtcg ctttcctcgc cttccagtct gcggatctca
    36301 cctttaaact gcacgccgcg aattaacgct accgttttcg gctgaccgtt taccgttccg
    36361 gcaattgccg cctgcggccc gctcatctgc gcatgacgcg ttttttcttc cgtcaaaatg
    36421 tagaaggcga ctttctgcgc atcaaaaaga taaaaggcat tggcgcacca cagttcccct
    36481 tcctgctgca cacaccaggt gacaacatgt tgttttgcca gccaacggct gatggcggtg
    36541 agtgtttcca ttgctgttct cttttatact gtgggcctga ccttaacatg cgacgcagac
    36601 gatgacaccc tggtttcttt acttgatccg taccgccgac aataagcttt ataccgggat
    36661 caccacggat gtcgaacgcc gctatcagca gcaccaaagc ggcaaagggg cgaaagcact
    36721 gcgagggaaa ggagaactaa cgctggcgtt ttccgcgcca gtgggcgacc gttcgctggc
    36781 actacgagcg gaatatcgcg ttaaacaact gactaaacgg caaaaagagc gtctggtaac
    36841 ggaaggcgca gggtttgcag aactgttgag cagcctgcaa accccggaga ttaaaagcga
    36901 ttgaaatgct cgtgatactc gaccagacca gttacgccgt tcagcgcgtc atccgctaaa
    36961 cgatgtacct ggaaggcgct ttcagtgccc ggccagcggc aatgcagatc gtgatgcgcc
    37021 gccagttcaa agccgaaacg gctgtacagc gccggatcgc ccagcgtcac cactgcggca
    37081 tagccgaact cattaagcga atcgagtcct tcatagacca gttggcgtgc cagcccctgt
    37141 ccacggtatt tttcatcaac cgccagcggt gccatgccga cccattgcag gtcttcgccc
    37201 tgcacatcaa ccggactaaa agccacatag ccaatgacct gaccttcgtc atctgtcgcc
    37261 accagcccca gcgtcagaaa gccatcttca cgcagatcgt gaaccagctt cgcttccgca
    37321 tcactttcga atgaacgacg cagcagggca tcaatacccg gcgcatcaat gggaatttct
    37381 actcgaatta gcatggttca cctaccgatg tctgtttggt ttcaggcgcg gttttcattc
    37441 ccgcctcaac aaaatccgcc agttgcagca gcatcatgcg taaggctttc ggcatttgct
    37501 ccagttcaat ggcgtccatc aggtttttca catacagccc cagctccgta tcgccttcaa
    37561 tcaccagccg acgctggaag aagagcgtat ccggatcttg tttacgcgcc gcaatcatca
    37621 gcagatcgct ggcgtcggca ctaaaactca catcagcttg cgcgttctgg ctaacgacca
    37681 gtttgccatt caccaccgag gtaaaccatt gcaggtcaat atcacgcaca tgaatactta
    37741 accagcgacc ttcaagaaac tccagctcgc catcatccag cgcctgacgg aattgccagc
    37801 ttaagacctg ctcaagaacc tggcgtttta gcgcaaatgg cgtcagtttt accggtacac
    37861 tcaacagaga tggccccaaa tgcacaatac gggaacgcag tttatccaac acgagtttta
    37921 ctccctgttt caacaatcat cctattttgc catatcagaa aaataacata gcggtataaa
    37981 tcaacaattc catatgaaat tgctgctacc accaatacaa ctttaactgc cttaaatcaa
    38041 aaattgtcgc agcaaggtta actaaaatcc cagttcgtta acatttttgc gttttgatag
    38101 cgcaaccttc aggaaaaatt atggagctgc tctgccctgc cggaaatctc ccggcgctta
    38161 aggcggccat cgaaaacggc gcagatgctg tttatatcgg gctaaaagat gataccaatg
    38221 cccgtcactt cgccggcctt aactttaccg agaaaaaatt gcaggaagcg gtgagttttg
    38281 tccatcaaca tcgccgcaaa cttcacatcg cgattaacac ttttgcgcat ccggacggtt
    38341 acgcccgttg gcagcacgcc gtggatatgg cggcgcaact gggtgccgac gcgctgatcc
    38401 tcgccgacct cgccatgctg gagtacgccg ccgaacgtta tccgcatatt gagcgccacg
    38461 tatcggtgca ggcttcggcg accaatgaag aggcgattaa cttttatcat cgccattttg
    38521 acgttgcccg cgtggtactg ccgcgcgtgt tgtcgattca tcaggtgaaa cagctggcac
    38581 gggtcacacc tgtaccactg gaagtgtttg ctttcggcag cctgtgcatt atgtcggaag
    38641 gccgttgcta tctgtcgtcg tatctgacgg gtgaatcgcc caacaccgtg ggggcatgtt
    38701 ctccggcccg tttcgtgcgc tggcagcaaa cgccgcaagg gctggaatcc cgcctgaacg
    38761 aagtgctgat cgaccgttat caggacggcg aaaacgcagg ttatccgacg ctgtgtaaag
    38821 ggcgttatct ggtggacggc gagcgctatc acgcgctgga agaaccaacc agtctcaata
    38881 ccctggaact gctgccggag ttaatggcgg cgaatattgc ttcggtgaaa attgaaggcc
    38941 gccagcgtag cccggcgtat gtcagccagg tggcgaaagt ctggcgtcag gctatcgacc
    39001 gttgtaaggc cgatccgcaa aacttcgtac cgcaaagcgc gtggatggag acgctcgggt
    39061 cgatgtccga aggcacgcaa actacccttg gcgcgtatca ccgtaaatgg cagtgagaaa
    39121 agcaatgaaa tattccttag ggccggtgct atggtactgg ccaaaagaga cgctggaaga
    39181 cttttatcag caggccgccg ccagcagcgc agacgtgatt tatcttggtg aagcggtatg
    39241 cagcaagcgc cgggcaacca aagttggcga ctggctggag atggcaaaat cactcgccgg
    39301 aagtggtaag cagattgtgc tctccacgct ggcgctggtg caggcatcct ctgaactggg
    39361 cgaactgaaa cgctatgttg agaacggtga gtttctgatt gaagccagcg atctcggcgt
    39421 ggtgaatatg tgcgctgaac gcaaactgcc gttcgtcgcc gggcacgcgc tgaactgcta
    39481 caacgcggtg acgctgaaaa tattgcttaa acagggcatg atgcgctggt gtatgccggt
    39541 ggagctttcc cgcgactggc tggtgaatct gcttaatcag tgcgatgagt tgggcattcg
    39601 caaccagttt gaagtggaag tcctgagcta cggtcatcta ccgctggcct actccgcacg
    39661 ctgctttacc gcgcgttcgg aagaccgccc gaaagatgag tgtgaaacct gctgcattaa
    39721 gtatccgaac gggcgcaacg tactgtcgca ggaaaaccaa caagtgtttg tactcaacgg
    39781 cattcagacc atgagcggct acgtttacaa cctcggtaac gagctggcat ccatgcaggg
    39841 gctggtcgat gtggtccgcc tgtcaccgca gggtactgac actttcgcaa tgctcgatgc
    39901 cttccgcgct aatgaaaatg gcgctgcgcc actaccgttg acggcaaaca gcgactgtaa
    39961 cggctactgg cggcggctgg ccgggctgga gctgcaagcg taagtatata gctcactttg
    40021 ttaacaactt taactactct ttaatgcagt attaaagact aatcggtaac aaagtgagct
    40081 gttatgactg ataaaaccat tgcgttttcg ctactcgatc tggcccccat ccccgaaggt
    40141 tcttcagcgc gggaagcgtt ctcccactct ctcgacctcg cccgtctggc tgaaaagcgc
    40201 ggctatcatc gctactggct ggcagaacac cacaatatga ccggcattgc cagtgctgca
    40261 acgtcggtgt taattggcta tctggcggcg aataccacca cgctgcatct ggggtctggc
    40321 ggcgtgatgt tgcctaacca ctcaccgttg gtcattgccg aacagttcgg cacgcttaat
    40381 acgctctatc cggggcgaat cgatttgggg ctgggtcgcg cgccgggtag cgaccaacgg
    40441 acaatgatgg cgctacgtcg tcatatgagc ggcgatattg ataatttccc tcgcgatgtc
    40501 gcggaactgg tggactggtt tgatgcccgc gatcccaatc cgcatgtgcg ccctgtaccg
    40561 ggctatggcg agaaaatccc ggtgtggttg ctaggctcca gcctttacag tgcacaactg
    40621 gcggcgcagc ttggtctgcc gttcgcgttt gcctcacact tcgcgccgga tatgctgttc
    40681 caggcgctgc atctttatcg cagcaacttc aaaccgtcgg cacggctgga gaaaccgtat
    40741 gcgatggtgt gcatcaatat tattgccgcc gacagtaacc gcgacgctga gtttctgttt
    40801 acctcaatgc agcaagcctt tgtgaagctg cgtcgcggcg aaaccgggca actgccgcca
    40861 ccgattcaaa atatggatca gttctggtca ccgtccgaac agtatggcgt gcagcaggcg
    40921 ctaagtatgt cgctggtggg cgataaagcg aaagtgcgtc atggcttgca gtcgatcctg
    40981 cgcgaaaccg acgccgatga gattatggtt aacgggcaga ttttcgacca ccaggcacgc
    41041 ctgcattcgt ttgagctggc gatggatgtg aaggaagagt tgttggggta gtgtgtttta
    41101 acgtaggaag ccttatccga gatggcaacg ctgtcctacg taggcctgat aagcgaagcg
    41161 catcaggcat tgtgtaggca gcagaaatgt cggataaggc acctctgatt actgatacac
    41221 cggcagcaca ttaaagctcg ataagatatg caccagtgcg ttgccgacgc caaacaccag
    41281 aatcagcaca atcatcggct tgccgcccca tacacggaat ttcgggctac caaagcgttt
    41341 acgcgatgcg cgggccagca gcgccggaac aattgccgcc cagatggtag ccgctaagcc
    41401 agcataacca atggcgtaca ggaatccgtt aggaaacagc aggccaccca caaccggcgg
    41461 ggcaaaggtc agcaacgctg ttttcaaacg gcccacagcc gagtcgtcga aaccaaacag
    41521 atctgccaga tagtcaaaca ggcccagcgt tacgccaagg aacgaactcg ctaccgcaaa
    41581 gtttgagaac acaaccagca gaaggtccag gctacggctg ttcagtacgc cgcttaacgc
    41641 ctgtaccagc acatcaatat taccgccctt ctcggcgatg ccgataaact ccggacgcgg
    41701 gatgttaccc atcgtcgcca gcaaccagat ggtatacagc gccagcgcca tcagcgtacc
    41761 gtacaccagg catttcacga tggttttcgg atctttgccg taatacttca tcaggctcgg
    41821 tacgttaccg tgataaccaa acgatgccag acagaacggc agcgtcatca acagatacgg
    41881 tgcataagac gcattgcttt cggcgacgtt gaacaatgtc gcaggctgca catgccccag
    41941 caggctaccg aaggtgagga agaaggtaat gactttcgcc cccagcacaa tcgctgtcat
    42001 gcgactgacg gctttggtgc tcaaccacac cacaaacgcc accaacagtg caaaaccaaa
    42061 acccgctgcc cgtgccggga cgtttagcga catctctgcg aaggtgtgat gcagaatcga
    42121 accactggca gaaatatagg cataggtcag gatgtagagc acaaaggcaa tggaaatgcc
    42181 gttgaccacg ttccagcctt tgccgagcag gtctttggtg atggtgtcaa agctcgaacc
    42241 gattcggtaa ttcaggttag cttccagaat catcaagccg gaatgcagca tacagaacca
    42301 ggtgaaaatc agcgccgcca ttgaccagaa gaaccacgcc ccggacatga ccactggcag
    42361 agaaaacatc cctgcgccaa taatggtgcc gccgataatc accacgccgc caagcagcga
    42421 cggtgacgtt tgggtggtgg ttagtgttgc catgagggct tctctccagt gaaaaatagt
    42481 gcgactgcgt tgttatgcat tgcactgtac cagtacatga gtacaaaaaa cagaaaaaaa
    42541 gccccgatgg gtaaaatcgg ggctgtatat attattttac agattgtgtt cgctgttcag
    42601 cgatgattac gcatcaccac cgaaacgacg acgaccggta gagtcatcac gacgcggtgc
    42661 gcggccttca cgacgttcgc cgctaaaacg acgcccatca ccacggccac cttcacggcg
    42721 ttcaccgctg aagttacgac cgccttcacg acgttcgcca ccgaaaccac gaccaccgcc
    42781 acgacgctca ccgccagtat gcggctgtgc atcgcccagt aactgcatgt tcattggctt
    42841 gttgagaatg cgagtacgcg taaagtgttg cagcacttca cccggcatac ctttcggcag
    42901 ttcgatggtg gagtgagaag caaacagctt gatgttaccg atgtaacggc tgctgatgtc
    42961 gccttcgtta gcaatcgcgc caacgatatg acgaacttca acaccatcat cgcggcccac
    43021 ttcaatacgg tacaactgca tatcgccaac atcacgacgt tcgcgacgcg gacgatcttc
    43081 acggtcgcca cgcgggccac ggtcgttacg atcgcgcgga ccacggtcat cacggtcacg
    43141 gaattcacgt ttcggacgca tcggcgcatc tggcggaaca atcagagtac gttcaccctg
    43201 tgccattttc agtagtgcgg ctgccagagt ttcgagatcc agctcttcac cttcggcagt
    43261 cggctgaatt ttgctcagca gtgcacggta ttgatccaga tcgctgcttt ccagctgctg
    43321 ctgtacttta gcggcaaatt tttccagacg acgtttgccc agcagttctg cgttcggcag
    43381 ttctacttcc ggaatggtca gcttcatggt gcgttcgatg ttgcgcagca gacgacgctc
    43441 acggttctca acgaacagca gtgcacgacc agcacgacct gcacgaccgg tacgaccgat
    43501 acggtgaacg taagactcag aatccatcgg gatatcgtag ttaaccacca ggctgatacg
    43561 ctcaacgtcc aggccacggg ctgcaacgtc ggtcgcaatc aggatgtcca gacgaccatc
    43621 tttcaggcgt tccagtgtct gctcacgcag cgcctggttc atgtcaccgt tcagcgcggc
    43681 gctgttgtag ccgttacgct caagagcttc tgccacttcc agagtcgcgt ttttggtacg
    43741 aacgaagata atcgccgcat caaaatcttc cgcttccagg aaacgtacca gtgcttcgtt
    43801 tttacgcata ccccagacag tccagtagct ctggctgatg tcaggacggg tagtcacgct
    43861 ggactgaatg cgcacttcct gcggctcttt cataaagcgg cgggtaatgc gacgaatcgc
    43921 ttccggcatg gttgcagaga acagagcggt ctgatgacct tccgggatct gcgccataat
    43981 ggtttcaacg tcttcgatga agcccatgcg cagcatttcg tcagcttcat ccagaaccag
    44041 accgctcagt ttagagaggt ccagagtgcc acgtttcagg tggtccagca gacggcccgg
    44101 tgtaccgaca acgatctgcg gcccctgacg cagggcgcgt aattgcacgt cataacgttg
    44161 gccgccgtac agggcaacca cgtttacgcc gcgcatgtgt ttagagaaat ccgtcattgc
    44221 ttcagcaacc tgtaccgcca gttcgcgggt cggtgccagc accagaatct gtggtgcttt
    44281 cagctcagga tcaagattct gcagcagagg taaagagaat gctgcagttt ttccgctccc
    44341 cgtctgggcc atacccagaa cgtcgcggcc attcagcaga tgtggaatac actctgcctg
    44401 aattggagat ggtttttcgt aacccagatc gttaagggct tcaaggatag gagccttcag
    44461 gcccagatct gcaaaagtgg tttcgaattc agccatgtag tacgtgtgcc tcaaaattaa
    44521 tggcggccag tctacataac tcatcatgaa attgatcagc aattttcatt gaaaagtgtg
    44581 aaccggctca aagtaggtgt attaacgaac aacaacgccc tcacccgtta aggtgatggc
    44641 aatcaaaaaa gattacgggc tgatgtgtac gtcagctatt gctggtccga ttctgccagg
    44701 tcatcttggt cctggcccag gagcgataat tccaacaatg cgtatcggtg ctcaacaaag
    44761 ttatgaacgt tgttggcaac cgccagtttg aacagtgccg tggcgctgtc caaatccccc
    44821 agacttaggt agtacttacc taaatagaag ttggtttcac tgagatgctc agcgagcgag
    44881 gtgttatccg ttgcgtccgc cttgagcctt tccattaacg tttgttcgct aatgttgccc
    44941 aggtagaact cgacaatgtt ccatccccac tgttccttat ccgatttttc gaagtgctgt
    45001 ttcaacactt ctttagcctg cttctcatcg agcttctgct cggcgagata aagccacaga
    45061 ctacggaaag gatcattggg atcgtcttga taaaacgcca gcagatcatc ttgcgctaac
    45121 ttgtcacgac cgccgtaata taatgcgatc ccgcgattca agtgcgcgta gttgtaagtt
    45181 ggatcaagct caagtacaga atcaaacgct tcataggcag catcaaaatt gcctgcctgc
    45241 gttaaatata tgcctaagta attgaatact tcaggcatat ccggtcggat tgccagcgct
    45301 tgcgaaaaat cgttacgcgc taatgccctc agaccgagac tatcatacaa cactccgcgc
    45361 tcatataaaa gctgtgcgcg ttcgtcatcg gttaaagccc gactggcaag gatttgttcc
    45421 atacgtgcca gaatcacttc ctgctgtaaa gtcggttgca atggtaccgc gaggacttca
    45481 cttttacgcc aggaagtatt actgcatcct gcaagcgtaa gtgctgtcgc aacgaaacac
    45541 cagcgcaaaa aaggcttcat ttcccactcc cgaagaccac ggttgaatga acgtcctgtt
    45601 cccggttgct aacaaggcgt cctgcccggt taaaagcccc ccgccgcagc ggagggcaaa
    45661 tggcaacctt actcgccctg ttcagcagcc ggagcttccg gtgctgcagc aggttgagac
    45721 tgctcagtcg cttctttaat gctcagacgg atacggccct ggcgatcaac ttccagaact
    45781 ttcaccggta cttcctgacc catctgcagg taatcggtca ctttctcaac gcgtttatca
    45841 gcgatttgag agatgtggac cagaccttct ttaccgccgc cgatggcaac aaatgcgcca
    45901 aagtcaacga ttcgggtcac tttaccattg tagacgcggc ctacttcgat ttctgcagtg
    45961 atctcttcga tacgacgaat agcgtttttc gccttctcgc cgtcggtcgc tgcgatcttc
    46021 acagtaccgt catcttcgat ttcgatggta gtgccagttt cttcggtcag agcacggatt
    46081 acagaaccgc ctttaccgat aacgtctttg atcttgtctg gattgatctt gatggtatgg
    46141 atacgcggag cgaactcaga gatatcaccg cgcggcgcat tgatcgcctg ttccattacg
    46201 cccaggatat gcagacgcgc acctttagcc tggttcagtg caacctgcat gatctctttg
    46261 gtgatacctt caattttgat atccatctgc aatgcagaga taccgtcacg agaacccgca
    46321 actttgaagt ccatatcgcc caggtgatct tcgtcgccca aaatgtcaga cagtacaacg
    46381 tagttgtcgc cttctttcac cagacccatt gcgatacccg caacggcagc tttgatcggc
    46441 acaccggcgt ccatcagcgc cagagacgcg ccgcacacgg aagccataga agaggaaccg
    46501 ttggattcgg tgatttcaga cacaacacgt acggtgtacg ggaatttgtc catatccggc
    46561 attactgcca gcacgccgcg cttcgccaga cgaccgtgac caatttcacg acgcttcgga
    46621 gaaccgacca tgccggtttc gcctacggag tacggaggga agttgtagtg gaacaggaag
    46681 gtatcggtac gttcgcccat cagttcatca agaacctgcg cgtcacgagc agtacccagc
    46741 gttgcggtaa ccagcgcctg cgtttcacca cgggtgaaca gcgcagaacc gtgagtacgc
    46801 ggcagcacac cagtacgcac atccagacca cggatcatat ctttttcacg accgtcgata
    46861 cgcggttcgc cggccagtac gcggctacga acaacatttt tctcgatagc gtgcagaatt
    46921 tcacccagtt cgttttcgtc cagggtttcg tcttcagcaa gcagtgtcgc gatggtttca
    46981 gatttgatga catcaacctg cgcataacgc tcttgtttgt cggtgatgcg gtaagcatcg
    47041 ctcagacgag cttcagccag cgcagcaacg cgcgcgttca gcgcttcgtt taccggctcc
    47101 ggctgccaat cccaacgcgg tttaccggct tctttcacca gttcattgat gttctgaata
    47161 acaacctgct gttgttcatg accgaacacc actgcgccca gcatttggtc ttcgctcagc
    47221 agttcagctt cagattcaac catcagcacg gcagcttctg taccggcaac aaccaggtcc
    47281 agtttgctct ctttcagttc gtcctgagtc gggttcagta cgtactggtc attgatgtaa
    47341 cctacacggg cagcaccaat cgggccattg aacggaatac cagacagaga cagtgctgcg
    47401 gaagcaccaa tcatcgcgac gatatccggg ttaacctgcg ggttaacaga aaccacggtg
    47461 gcgataacct gaacttcgtt gacgaagcct tccgggaaca gcgggcgaat cgggcggtca
    47521 atcagacgcg cgatcagggt ttcgccttcg cttgggcggc cttcacgacg gaagaagcta
    47581 cccgggatac gaccagcagc gtaggtacgc tcctgatagt taacggtcag cgggaagaag
    47641 tcctgacctg gtttggcttt tttctgacca acaacggtaa caaataccgc ggtgtcatcc
    47701 atgctaacca taacagcggc agtagcctga cgagccatca tgccggtttc cagagtcacg
    47761 gtgtgttggc cgtactggaa tttacgaacg atcggattaa gcaatgtaat atcctttctc
    47821 tttcttagac agtaccttac ggtactggtg ttaatacccg atcttctgcg catcctcgcg
    47881 actaatgaca accctaaccc agctctatgt gggtaaagcc tctcattagc cgcgcgaacc
    47941 tctgcaacgg aagatcattc atagcaacaa tacattagtt tccagtgaat tgctgccgtc
    48001 agcttgaaaa aaggggccac tcaggccccc ttttctgaaa ctcgcaagaa ttagcgacgc
    48061 agacccaggc gctcgatgag ctgggtgtaa cgtgctacgt ctttacgttt caggtagtcg
    48121 agcagtttac gacgctgaga aaccatgcgc agcagaccac gacggctgtg gtgatctttt
    48181 ttgtgctctg caaagtggcc ctgcaggtgg ttgatctgtg cagtcagcag tgctacctga
    48241 acttcggtag aaccggtgtc gtttgcgtca cgaccaaact cagaaacgat tttagctgtt
    48301 gcttcagtac ttagagacat tttaaaactc caaagtatat agaatgaaag gacgccgatc
    48361 tctaattcag cgatcccagt gtacgttacg caaagtgtta aacaatttac gcgacgttaa
    48421 gcggcagtat tctactcgta gcgacctgtt atcgcaagac ggttaacatt acgccgggta
    48481 ttcaaccacc aggcgacgag gcgcaacgcg gccttcatcg tcaatttcgc ccataccgat
    48541 aaacttgccg ttctcaccct ctgtaacgcg aaccagtcct tccagcggcg caccggatgt
    48601 acgaactggg ttaccatttt tgaagtaaac agaagacgtt aacggaagat tcaccactgg
    48661 gtagtccgaa gctggactgt ccattggcat cagtaatggg tcaagtaact ccgcagccgg
    48721 aatatcctgc tgttcggctt gctcaaccag ttcacgcaga tgttccaggg tcaccatccg
    48781 ttcaaccgga tatttactta ccgccagacg acgcaagtaa ataacatgcg cgccacaacc
    48841 gagtttttcg ccgagatcgt caatgatagt gcggatataa gtgccttttg agcagtgaat
    48901 ttccagctcc agctcattgc cttcatggcg aataaacagc aattcataaa cggtaatcgg
    48961 gcgcgcttca cgtggaactt caatgccctg acgcgcgtat tcgtacagtt ttttgccctg
    49021 atatttcagt gctgaataca tcgaaggaat ctgttcgata tcgccacgga aggtatccag
    49081 cgccgccgcc agttgctctg cactaaaggt taccggacgt tcttcaacga tttgtccgtc
    49141 ggcatcagaa gtatcggtac gctgtccaag acgcgcaatg acccgataac gtttgtcgga
    49201 gtccagcaga tactgggaaa acttcgtcgc ttccccgagg caaattggca acatgccggt
    49261 cgccagcggg tccagcgcac cggtatgccc ggcacggttg gcgttataaa tccgtttcac
    49321 tttttgcagc gcatcgttgc tggacatccc ctgcggttta tccagcaaca aaacgccgtt
    49381 aatgtcgcga ccgcgacgac gaggacgact cattagtcct ccttgctgtc gtccgggtta
    49441 acacgacgtt cttcgtcatg tttgaccacg ctggtcacca ggtttgacat gcgcatccct
    49501 tcaaccagag agttgtcgta gaagaaggtc agttccggca cgatacgcag gcgcatcgct
    49561 ttccccagca ggctgcggat gaaaccagaa gcttcctgca acgctttgat gcccgcttta
    49621 accgcgtctt catctttgtc gttgaggaac gtcacatata ctttggcata cgccaggtcg
    49681 cgagacattt cgacaccgga aacggtggtc atcatgccca gacgaggatc tttaatttca
    49741 cgctgcagga tgagagcgat ctctttttgc atttcctgcg ctacgcgctg cgggcgacca
    49801 aattctttcg ccataataaa ttctcctgac aaaaaagggg ctgttagccc ctttttaaaa
    49861 ttaatttcag gtggaagggc tgttcacgtt ggcctgataa gacgcgccag cgtcgcatca
    49921 ggcaatccat acaggatgcg gcataaacgc cttatcccgc atggaaccct aaaaacctta
    49981 agcgatggta cgttggatct cgatgatttc gaatacttcg atcacatcgc cagtgcggac
    50041 atcgttgtag ttcttaacgc cgataccaca ttccataccg ttacggactt cgttaacgtc
    50101 atctttgaag cgtcgcaggg actccagctc gccttcgtag ataaccacgt tgtcgcgcag
    50161 aacgcggatc gggttgtgac gtttaaccac accttcggta accatacaac ctgcgatagc
    50221 accaaatttc ggtgatttga acacgtcacg aacttccgcc agaccgataa tctgctgttt
    50281 cagttccgga gacagcatac cgctcatcgc cgctttcact tcgtcgatca ggttatagat
    50341 gacggagtag taacgcagat ccaggctttc cgcttcaatc actttacgtg cagaggcatc
    50401 agcacgtacg ttgaagccaa ccaggatggc gttggacgcc gcagccaggg tagcgtcggt
    50461 ttcggtgata ccacctacgc cagaaccgat gatcttcact ttaacttcgt cagtagacag
    50521 tttcagcaag gagtcagaaa ttgcttccac agaaccctgt acgtctgcct tcaggacgat
    50581 attcacttcg tgaacttcgc cttcggtcat gttggcgaac atgttctcga gtttagattt
    50641 ctgctgacgc gccagtttaa cttcgcggaa tttaccctga cgataaagtg caacttcacg
    50701 cgctttcttc tcgtcacgta caacggtaac ttcatcaccc gcagccggta cgccggacag
    50761 gccgaggatt tccaccggaa tggacggacc cgcttccagc acttcctgac ccagttcgtt
    50821 acgcattgca cgaacacgac cgtattcgaa gccacacaga acgatatcgc ccttgtgcag
    50881 agtaccttca cgtaccagaa cggtagcaac cggaccacga cctttatcga ggaaggattc
    50941 gataaccgca ccgctcgcca tacctttacg taccgctttc agctccagaa cttccgcctg
    51001 cagcaggata gcatccagca gttcatcaat accggtaccc gcttttgcag atacgtgtac
    51061 gaactggctt tcgccgcccc actcttctgg caggatgccg tactgggaga gttcgttctt
    51121 aacgcgatcc ggatcggctt ctggtttatc gattttgttc acagcaacca ccaccggaac
    51181 acccgccgct ttcgcgtgct ggatagcttc gatggtctgc ggcattacac cgtcgtctgc
    51241 agcaacaacc aggactacga tgtccgttgc ctgcgcacca cgtgcacgca ttgaagtaaa
    51301 cgcggcgtgc cccggggtgt ccaggaaggt gatcatgccg ttttcagttt caacgtggta
    51361 tgcaccaatg tgctgggtaa tgccgcccgc ttcgccagag gccactttcg ttgaacgaat
    51421 gtagtccagc agagaggttt taccgtggtc aacgtgaccc atgatggtca caaccggcgc
    51481 gcgcggttca gccgcagcac ccgtgtcacg gtcgctcatt accgcctctt ccagctcgtt
    51541 ttcacgacgc aggataactt tgtggcccat ctcttcagca accagctgtg cggtttcctg
    51601 atcgataacc tggttgatgg ttgccattgc gcccagtttc atcatcgctt tgatgacctg
    51661 agagccttta accgccatct tgttcgccag ttcgccaacg gtgatggttt cgccgatcac
    51721 aacgtcacgg ttaacggcct gagctggctt ctggaagcct tgctgcagcg aagaaccttt
    51781 acgttttccg cccttaccgc cacgtactgc tgcacgagct tcttcacgat cagcttttga
    51841 ttcagcgtgt ttgttgcctt tcttcggacg cgctgctttc gcgttacgac cacggccacg
    51901 gccgccttcg acttcacgat cgctttcgtc ttctgcctgg cgagcatgtt gagaagtagt
    51961 gacgtgataa tcgctggaat cttcagtcgg ttccgcgtta tcagtccatt tgttttcttc
    52021 cgccatacga cgtgcttctt cagcaacgcg acgtgcttct tcttcgagtt tacgacgcgc
    52081 ttcttcttcg gctttacgct tgagctctgc agcttcctgc tcacggcggg ctttttcagc
    52141 ctgggcgttt ttagtcatat cgtcttgttg attgctcact ttgtcttttt ccgcagcttc
    52201 acgtttcgct tgttcagcag cttcacgctt agcttgttct gcggcctcac gttcagcttt
    52261 ttgttgcgcc tcgcgtttag ccgattcttc tgcctcacga cgggcttgct cttccgcttc
    52321 acgctgcgct tgctcttccg ctgcaaggcg ctcagcctct tgcggatcgc gtttcacaaa
    52381 ggtgcgtttc ttgcggactt cgatttgtac cgatttgctt tttccaccgg taccaggaat
    52441 gttaagggtg ctgcgtgttt tacgttgcag cgtcaatttg tccgggcctg aatttttctg
    52501 attcaggtgg tcaatcaaag tctgtttctc ttgtgcagac acagagtcgt cagcagactt
    52561 ccggatacct gcatcagcaa attgctgtac caggcgttcc acggaggtct gtcgctctgc
    52621 ggccagcgtt ttaatcgtta catctgtcat gctgttcctt cctgctacag tttattacgc
    52681 ttcgtcaccg aaccagcaaa tattacgggc agccataatc agtgctccgg ctttttcgtc
    52741 ggtcaaccct tcgatatcag ccagatcatc aatgccctgt tcggcgagat cttccagcgt
    52801 acaaacgcca cgggcggcca gtttgaatgc caaatcacga tctacccctt caaggttcag
    52861 cagatcatca gccggtttgt tatcaccgag gctttcttcc tgggcctgtg caatggtggc
    52921 cagtgcattt ttagcacgct cgcgcagtgc ttcaacggtc ggctcatcaa ggccttcgat
    52981 ttccaacagc tctttcatcg gcacataggc cagttcttcc agcgtcgaga agccttcttc
    53041 taccagaaca gtcgcgaagt cttcatcgat gtcgagatat ttggtgaagg tgtcgatcgc
    53101 tgcgtgcgct tccgcctgat gcttagcctg caggtcgtca acggtcatca cgttgagttc
    53161 ccaaccgctc agctgcgaag ccagacgcac gttctgaccg ttacggccaa tcgcctgcgc
    53221 caggttaccg gcttcaacgg cgatatccat ggtgtgttta tcttcatcca ccacgataga
    53281 agcaacgtct gccggtgcca ttgcgttaat cacgaactgc gccgggttat catcccacag
    53341 gacgatatcg atacgctctc cgcccagttc agtagaaacc gcctgaacac gcgcgccacg
    53401 catacctacg caagcaccta ccggatcgat acgtttatcg ttggttttca ccgcaatttt
    53461 cgcacgagat cccgggtcgc gagccgctgc tttaatttca atcacttctt cgccgatttc
    53521 cggcacttca atacggaaca gttcgatcag catttccggc ttggagcggg tgacgaacag
    53581 ctgcgcgcca cgcgcttccg ggcgaacgga atagagcacg ccacgaacgc ggtcgccagg
    53641 gcggaagttt tcacgcggca gcatatcttc gcgcaggatc acggcttcag cgttgttgcc
    53701 cagatccaga gagatgttgt cgcggtttac ttttttcacc acgccggtga tgatttcacc
    53761 ttcgtgttca cggaactgat caaccaccat cgcacgttcg gcttcacgca ctttctgcac
    53821 gataacctgt tttgccgtct gggtagtgat acgatcaaag gtaacagact caatctgatc
    53881 ttcaacgtaa tcgcccaagt tcaggctttc atcttcataa cgtgcggctt caagggtgat
    53941 ttccttggtc ggctgggtga cttcatcaac aactaaccag cgacggaagg tgtcaaaatc
    54001 accgcttttg cgatcgatct gtacgcgaac gtcgatttct tgttcatatt ttttctttgt
    54061 tgctgtcgcc agcgcgcttt ccaatgcttc gaaaatcttc tcgcgaggta gcgccttttc
    54121 attggatacg gcttcaacta cagccaaaat ttctttgttc atcgcgggct tttcacctca
    54181 tccagactat taaaagtggg gaaccaggtt cgccttctgg atattactca gcgcgaacac
    54241 ttcatcttta ccttcgacgg taactgtgat catttcaccg tctaccgctt tgataacgcc
    54301 ctgccattta cgacggtttt gtaccgccat acggagaacc agagtcacct cttctccgac
    54361 aaaacgggcg tagtgttcag ccgtgaacag tgggcgatcg agacccggtg aggagacttc
    54421 caggttataa gcaacggtga tggggtcttc aacatccagc acagcactta cctggtggct
    54481 cacatcagca caatcatcaa cattgatgcc atcttcacta tcaatataga tgcgcagtgt
    54541 ggatgtgcga ccgcgaataa attcgatgcc aaccagttca aaacccaggg cctcaactgg
    54601 cgcagtaatc atctctgtta atttttgctc taatgtggac aagcccaccc ccaagacata
    54661 aaaaaagggc ctaaagccca gttattctgt agtcagataa caaaaaaccc cgataaatcg
    54721 gggctttata taactgaacc ctataaccgc aactgcggtc tggagcactt tccagaagga
    54781 ttttttcaaa tcccactacg aaggccgaag tcttcacagt atatttgaaa aaggactcta
    54841 agggaaagtg gttgcggggg ccggatttga accgacgacc ttcgggttat gagcccgacg
    54901 agctaccagg ctgctccacc ccgcgcctga aacgtggcaa attctactcg ttttgggtaa
    54961 aaaatgcaaa tactgctggg atttggtgta ccgagacggg acgtaaaatc tgcgggcatt
    55021 atagtgatcc acgccacatt ttgtcaacgt ttattgctaa tcacgtgaat gaatatccag
    55081 ttcactttca tttgttgaat acttttacct tctcctgctt tcccttaagc gcattatttt
    55141 acaaaaaaca cactaaactc ttcctgtctc cgataaaaga tgattaaatg aaaactcatt
    55201 tattttgcat aaaaattcag tgagagcaga aatccaggct catcatcagt taattaagca
    55261 gggtgttatt ttatgacgac gattctcaag catctcccgg taggtcaacg tattggtatc
    55321 gctttttccg gcggtctgga caccagtgcc gcactgctgt ggatgcgaca aaagggagct
    55381 gttccttatg catatactgc aaacctgggc cagccagacg aagaggatta tgatgcgatc
    55441 cctcgtcgtg ccatggaata cggcgcggag aacgcacgtc tgatcgactg ccgcaaacaa
    55501 ctggtggccg aaggtattgc cgctattcag tgtggcgcat ttcataacac cactggtgga
    55561 ctgacctatt tcaacacgac gccgctgggc cgcgccgtga ccggcaccat gctggttgct
    55621 gctatgaaag aagatggcgt gaatatctgg ggtgacggca gcacctataa aggaaacgat
    55681 atcgaacgtt tctaccgtta cggtctgctg accaatgctg aactgcagat ttacaaaccg
    55741 tggcttgata ctgactttat tgatgaactg ggcggccgtc atgagatgtc tgaatttatg
    55801 attgcctgcg gtttcgacta caaaatgtct gtcgaaaaag cttactccac ggactccaac
    55861 atgcttggtg caacgcatga agcgaaggat ctggaatacc tcaactccag cgtcaaaatc
    55921 gtcaacccaa ttatgggcgt gaagttttgg gatgagagcg tgaaaatccc ggcagaagaa
    55981 gtcacagtac gctttgagca aggtcatccg gtggcgctga acggtaaaac ctttagcgac
    56041 gacgtagaaa tgatgctgga agctaaccgc atcggcggtc gtcacggcct gggcatgagc
    56101 gaccagattg aaaaccgtat catcgaagca aaaagccgcg gcatttatga agcccctggg
    56161 atggcactgc tgcacattgc gtatgaacgt ttgttgaccg gtattcacaa cgaagacacc
    56221 attgagcagt atcacgcgca tggtcgtcag ttgggccgtc tgctgtacca gggacgttgg
    56281 tttgactccc aggcgctgat gctgcgggac tctctgcaac gctgggttgc cagccagatc
    56341 actggtgaag ttactctgga gctgcgccgc gggaacgatt attcaatcct gaataccgtc
    56401 tcagagaacc tgacctacaa gccagagcgt ctgacgatgg aaaaaggcga ctcggtgttc
    56461 tcgccagatg atcgtatcgg tcaactgacc atgcgtaacc tggatatcac cgatacccgc
    56521 gagaaacttt tcggttatgc caaaactggc ctgctctcct cctctgccgc ttcaggggtg
    56581 ccgcaggtgg agaatctgga aaataaaggc cagtaattcg acatcaaccc tgcccttcag
    56641 gggtggggtt accttgatta tcctctgtaa actcctttct gagcatcaca taatcgaaaa
    56701 catcatggtt tgcatccaca acccgcgagt ctcctttata gtgtgcaatc acttcctcaa
    56761 gcgtttgcgg ctgttccggc tttgttaccc ccatccacgc attaataatg taattattgt
    56821 aagctgtcga aaagatgttg ttttccgttg tgcgatccac gccatcccca agaacggggc
    56881 tataccagat aaacataggg acatgatatg cctgctggct agcctccctg cctccatgaa
    56941 aatagacgtt cttcttcgta gggtcgcgtt ccaggccgtg gtcggcaaaa tacatgaccg
    57001 aggcgcggcg atcttttaat aattcaaaaa cctgacctag caaactatct gtgtaatgaa
    57061 tggagttgtc atagcaggca tcctgatcgt cctgcggttg aaacacagcg ctggattgcg
    57121 gataggcgct acaagccggt tcatggcttc catttaaatg aagaacaatc agtttctttt
    57181 gctgcgtctt ttgctgtaac gcttgcgata aatgcggcaa caacaattca tcaaatcctc
    57241 tgacatagac tgtttccatg gcgcgcatgg cgatactggt aactgctgta ccattctgcc
    57301 gaaaagcgga ttgcgagctt agccagaaag tctgaaatcc tgcttgatta gccatattaa
    57361 taatgttgtc cggataatta tgaatgtcat gactcaaaac agaatcagca gttaaagaaa
    57421 ggggaaccga cagcgcagtg taaggtgcac cgcttattgc ttgattaaac agtttgatct
    57481 gctttctttg tgcttcgact tgcggtgtcg tagagtgtgt atatccatac aaagacatat
    57541 tgtcgacacg tacagactcc cccacaatca acacgtaggt atcaatacct gtatccctga
    57601 ctgataattg aaaatacggc accgtgtttg caattgagag taatctttga tgctctttcg
    57661 ctgctaaagc aaaataattg agattgaaaa acggcgtata ggtagcaaat cgcgacgcta
    57721 gtatatatgg actgaacgcc tctttatttt ttgcatcttt ataagcaaat tgacaagcgg
    57781 aaaataaact gcccgaaatg acaatcagca ataatattcc tgtcactttt tttgtcggca
    57841 aggaaacatc atattttatt attactgcca aaaaaagaag ggataaaaag gcaaaagcac
    57901 atagataagg gatatacatt cccagcattt tgacaacttc atccggatca ctctgcagca
    57961 cactaatcgc aaatccatca ttgaaagttg taccaaagat acaccatgaa tagaggctaa
    58021 tactcatatc tgccgcagtc agtaacacaa atggtgcggc aataagcagg cgaagcggaa
    58081 gggatggtat acgtttaaca accaggatgg tcagaacgaa gaacagcaat cgctgaacca
    58141 tatgcgctcc ggaagaagcg actaagttcg taataccaaa aataataaca caaagataca
    58201 acaaccaatg agatttaaaa cttttaacaa atttgttgaa tactgtcatc cagaaatcca
    58261 agttcacaac caatataaac aattatcaac aatgttcaat tttatatcag acatgttttt
    58321 caactctaat ccatatcaga ccgaaacact gctagatttt ttctttttaa atgatgcggc
    58381 cattgcgttc tcagtaatta aataacatta tcaatgcgtc tctaaacatt acgcagaacg
    58441 tagccatcag tagttatact gacaggggca ggatggttta tcgagaagta aacatatccg
    58501 tattcgtacc ggaaatggag ttgacacaat aaagtgccaa ttatgtcagc agaagggaaa
    58561 agcttataac taaggcatac cggcaccatc gtttcaaggt accagctacg agtaaaacaa
    58621 ctggacgaga tacagatacc tgacaaccat tcctcagacc aggaccaaaa cgaaaaaaga
    58681 cgcttttcag cgtctttctg gaatttggta ccgaggacgg gacttgaacc cgtaagccct
    58741 attgggcact accacctcaa ggtagcgtgt ctaccaattc caccacctcg gcacggatac
    58801 tactttttag ttcgggatat cgctggtcgg cttagccgga gcagctggct gagtttgttc
    58861 ggttttcgcc ggcgcactca ggttttccca ttcgctacct ttattggttt tgttgctatt
    58921 gatgttaccc agcaccagac tgatgatgaa gaataacgtt gccagcagcg ccgtcatgcg
    58981 agtcatgaag ttaccagaac cacttgaacc aaacagcgta gcggaagcgc ctgctccgaa
    59041 ggaggctccc atatcagcgc ctttaccttg ctgcagcatg atcagaccaa caaggccaat
    59101 tgccacaata aggaaaacta ctaaaagagc ttcgtacata atcaacctgt tccttgcgga
    59161 gttgccgcgt accaatgctt caaccaataa agcgggaata tttaaccttt cccactgaag
    59221 cgggtgtgaa tactaaccaa agcgaatgac cttcgcaagg gcaattttat tgcattgtat
    59281 caactgcgga aaaaaacagc aaaaccgatg tgttcgctga gaaaaaaggc gacaatcgcc
    59341 gcctttttag ccagccattt atcgttttaa acggctttta ctgcatcggc gatgcggtgt
    59401 gcaaattcag tcacctgcgc ttcgtcttcg ccttccacca tcacgcgaat taacggttcg
    59461 gtgccggatt tacgcaacag cacacgtcca cggctaccca gcgccgcttc aacttctgcg
    59521 gtcacagctt tgactgattc atgctccaac ggatcgccgc tacctgcggt gtaacgcaca
    59581 ttaaccagaa tctgcgggaa cattttcatg ccgctgcaaa ggtcgtgcag gctcatatgg
    59641 ttacgcgcca tcgccgccag cacctgcaag ccagcaacaa tgccgtcacc ggtagtggtt
    59701 ttatccagca ggatcacatg accggagttc tctgcaccga tacgccagcc tttctcctgc
    59761 attttttcca gtacgtagcg gtcacccact ttcgcgcgcg caaatggaat acctaactgt
    59821 ttcagcgcca gttcaagccc catgttgctc atcaatgtac ccacagcacc accacgcagc
    59881 tggccctgac gaagaccttc acgcgcgatg atatacatga tctgatcgcc atcgacttta
    59941 ttgccttcat ggtcaaccat aatcacgcga tcgccgtcgc cgtcgaaggc aataccgaga
    60001 tccgcttttt cagccagcac acgagcctgg agcgcgcgaa cgtcggtagc ccccacttcg
    60061 gcattgatat ttacaccgtt cggctcacaa ccgatagcga taacgttcgc ccccagttca
    60121 cgcagcacgt tcggtgcgat gtgataagtc gcaccgtttg cacaatccac cacaatcttc
    60181 agttcactga ggctaagttc gttcgggaac gtggctttgc aaaactcgat ataacgaccc
    60241 gcggcatcaa cgatacggct ggctttaccc agttctgccg aatcaacaca gctgatctct
    60301 ttttccattt ccgcttcgat ggcttcttca actgcatccg gcagcttagt accgtcaata
    60361 gaaaagaatt taatgccgtt atcgtagaat gggttatgcg atgcagaaat tacaattcca
    60421 gcctctgcgc ggaaggtacg cgtcagataa gccacggccg gtgttggcat cgggccagtg
    60481 aagagcgcgg aaagaccggc agccgcaaga cccgcttcca gtgctgactc cagcatatag
    60541 ccagaaatac gcgtgtcttt accaataata atcttacgag agccgtggcg cgccagcact
    60601 ttacccgcgg cccaacccag cttaagcaca aaatcaggtg tgatcggcgc atcccctaca
    60661 cgaccacgaa tcccatcggt accgaaatat ttacgattac tcatagcgtt tgttttcctt
    60721 tgcagacaga gtggcttcca ccacccgcat cgcttctacg gtttctttga cgtcatgaac
    60781 acgaatgatg tgcgcgcctt gcattgcggc aatgaccgca caggccagac taccgctcag
    60841 gcgctcggac ggccccacgt tcagcaattg cccaatcatc gattttcgtg acatacccac
    60901 caacagcggc aggttgaaat ggtgaaattc agccaggcgc gccagtaatg aatagttatg
    60961 ggagagattt ttaccgaaac cgaatccggg gtcgagcaac aatttctctt ttgcgatacc
    61021 cgcctgctcg caacgtgcta tttgctcaat aaagtagcga ttcacttctg caaagacatc
    61081 gtcatacttc ggcgcttcct gcatggtttt tggatttccc tgcatatgca tcagacaaac
    61141 cggtaaaccg gtttctgcag ccgcctccag agcaccaggt tcggaaaggg agcggatatc
    61201 gttaataatg tgagcgccaa ctttcgctga ctcacggatg acttctggtt tggatgtatc
    61261 taccgagatc cagacttcga agcgttgagc aattgcctca accacaggaa taacacgttg
    61321 caactcttct tcaacgcaaa cttccgccgc ccctgggcgc gtggactcgc caccaacgtc
    61381 aatgatcgtc gcgccagcgt tgatcatcag attcgcatgt ttcaccgcat ctaacagcga
    61441 gttatgcgtg ccaccatccg aaaaggaatc aggcgtgacg ttgaggatcc ccattacgtg
    61501 aggatggcta aggtccagtg aagtaccctg ggcaaagagt ttcatgatgt tatccctggt
    61561 atgaattgat aagaaaaaac cccggagcac gccccggggt tttcggtaca aatacagtca
    61621 tctgatacgg gaacttactt gtcgcctaac tgctctgaca tggtgttacc cgggttcggc
    61681 gtacgcggtt catcaaccgg acgaggagcc tttggactac cattgtcgcc agaattgtta
    61741 gaagcgcctg gttcttccca gcccgctggc ggacgtacat cgcgacgtgc catcaggtca
    61801 tcaatctgcg gtgcgtcgat agtctcatat ttcatgagag catctttcat cgcatgcaga
    61861 atatccatat tgtcggtcag aagctgacgc gcacgattat agttacgctc aatcagtgct
    61921 ttcacttcct ggtcgatgat acgtgcagtt tcatcggaca tatgtttcgc tttcgctacg
    61981 ctacggccga ggaacacttc accttcttct tccgcgtaca gcagtggacc caatttctca
    62041 gagaagcccc actgggtcac catgttacgt gccaggttgg tcgcaacttt aatatcgttg
    62101 gacgccccgg tagaaacatg ttccggtccg tagatgatct cttccgccag acgaccaccg
    62161 tacagcgtgg agatctgact ttccagtttc tgacggctgg cgctgattgc gtcgccctca
    62221 ggcaagaaga aagtcacacc cagcgcacga ccgcgtggga taatcgtcac tttgtgcacc
    62281 ggatcgtgtt ccggcaccag gcgaccgata atcgcatgac ccgcctcgtg gtaagccgtc
    62341 gattctttct gcgcttccgt catcaccatg gagcgacgtt ccgcacccat catgattttg
    62401 tctttcgctt tctcgaactc aaccatcgaa acaacgcgtt tgttgccacg agcagcgaac
    62461 agtgccgctt cgttcaccag gttcgccagg tcagcaccgg agaaaccagg agtaccacgg
    62521 gcaatgattg ccgcgtcgat atcgggtgcc aatggtacgc gacgcatgtg aactttcagg
    62581 atctgctcac gaccgcgaac atctggcaag ccaaccacaa cctgacggtc gaaacggcca
    62641 ggacgcagca gggctgggtc gagaacgtcc ggacggttag tcgcagcgat aacgatgata
    62701 ccttcgttac cttcaaaacc atccatctca accagcatct ggttcagagt ctgttcacgt
    62761 tcatcgtgac caccgcccaa gcctgcgccg cgctggcggc ctacggcgtc gatttcatcg
    62821 ataaagatga tgcacggtgc cgctttcttc gcctgttcga acatgtcacg aacacgggat
    62881 gcacccacac cgacgaacat ttctacgaag tcagaaccgg agatagtaaa gaacggaact
    62941 ttcgcttcgc ctgcaattgc tttcgccagc aacgttttac cggtacccgg aggacctacc
    63001 atcaggacgc ctttcgggat cttaccgccg agtttctgga agcggctcgg ctcacgcaga
    63061 tactcaacca gttcagcaac ttcttctttt gcttcgtcgc agcccgcaac gtcagcaaag
    63121 gtggttttga tctgatcttc cgtcagcatg cgcgctttgc tcttaccaaa cgacatggca
    63181 cctttgccac cgccgccctg catttgacgc atgaagaaga tccagacacc aatcagcaac
    63241 agcatcggga accaggagat gaagatagaa gccagcaggc ttggttcttc aggcggttca
    63301 ccgacaacct tgacgttctt ggtcaacagg ttatccagta atttcggatc ctgaaccgga
    63361 atgtaagtgg tataacggtt actatctttc ttggtaacgt tgatttcacg tccgttgata
    63421 cgcgcttcac gaacctggtc gttattgacc tcttgtagga aggtagagta atccacctta
    63481 cggccattag actcgctggg cccaaagctc tggaatactg acatcagcac aacggcaatg
    63541 accagccaga gtattaggtt tttcgccatg tcactcaagg gattaacctc ttattacaac
    63601 tgtgttaaaa acagcgtcag gatactctat atccagcatc tttcaaactt tcgtctgaaa
    63661 tctcccggtt agggtttacg cccggtcgct acaatataca cttcccgcga acgtgcacga
    63721 gaagagtccg gcttacgaac tttgaccttc gtaaacaggg agcgaatttc ccttagatac
    63781 tcatcgaaac cttcgccctg gaacaccttc actacaaaac tgccacctgg cgctaataca
    63841 tcacgacaca tttctagcgc cagttccacc agatacatgg cacgggggat atccaccgcc
    63901 ggtgttccgc tcatgtttgg tgccatatcg gacatgacaa cctggacttt gctgtcgcca
    63961 acgcgctcca gcagtgcttt catcaccagt tcatcacgaa aatcgccctg aagaaagtcc
    64021 acaccaacga taggatccat aggtaaaaga tcgcaagcga tgatgcggcc tttgccgcca
    64081 atttgggtga ccacatattg tgaccaacca cccggagcag caccaaggtc gacaaccgtc
    64141 attcccggtt taaagagttt gtcactttgc tgtatttcat caagtttaaa ccaggcacgg
    64201 gaacgtaacc cctttttctg tgcctgttga acatatttat cgctaaagtg ttcctgaagc
    64261 cagcggctgg agctggcaga acgcttctta cctgtcattt aactttccca tggggataac
    64321 tcatcgtaac caattgcgta aatttttacg cgcctatttg gtgatatatg ggagatggcg
    64381 gtagaatgac ccgttttcaa tcccaacgta agcaaaaaat acgatgaatc tgagtactaa
    64441 acaaaaacag cacctgaaag gtctggcaca tccgctcaag ccagttgttc tgcttggcag
    64501 taatggtttg accgaagggg tgctggccga gattgaacaa gcgttagagc accatgaact
    64561 catcaaggtg aaaatcgcca ccgaagatcg cgaaactaaa accttgatcg tggaagctat
    64621 cgtgcgcgaa accggcgcct gtaatgtaca ggtcatcggt aaaacgctgg tgctttatcg
    64681 cccaactaaa gaacgtaaaa tctcgctgcc acgctaagat tatcctaaag ttacacacat
    64741 tcgctgtgta aaacgagggg ttttccgcag gcaggagagc aaaatgccac gctctgttcg
    64801 ttgataaaag gccgcatagc ggcctttttc ctttctttac aatacatcaa catcttgagt
    64861 attgggtaat tcttacaggt attccacctt aattacttca aattctactt cgccgcccgg
    64921 cgttttgatg accacaacat catcttcttc tttgccgatc aggccacgag caataggcga
    64981 gtttacagaa atcaggtttt gtttaaagtc agcttcgtca tcgccaacga tgcgataagt
    65041 ctgttcttcg tcagaatcga gattcagcac cgttacggta gcaccaaaaa taacgcgccc
    65101 attgttgggc attttggtga catcaatcac ctgcgcgttc gacagcttgg cttcgatgtc
    65161 tttgatacgg ccttcgcaga agccctgctg ttcacgagct gcgtggtatt cggcgttttc
    65221 tttcaggtcg ccatgctcac gcgcttccgc gatagcagca atgatttcag gacggcgcac
    65281 agatttcaga aaatccagct cttcgcgtaa tttttcagcg ccgcgtaagg tcatcggaat
    65341 agcttgcatt tgttatacct cttgaatatt cctgatgggg caagtcttca cccaccccgg
    65401 ctgttcggcc tgcccggcat aactcctcac cgggaccaga agcaaaaaaa taccgacccg
    65461 ggtacaagtc ccaggtcagc tacaattcac attttgatag tcattttacc ctggagttcc
    65521 cgaagggtca tcgtttactt tatagggcgt tgcgccgtag tatgacggct cgattccagg
    65581 ttgttagcgc gagattatgc gattttccag atttatcatc ggattgacca gctgtatagc
    65641 gttcagtgtt caggccgcaa atgttgatga gtacattact caactccccg caggtgccaa
    65701 ccttgccctg atggtgcaaa aagtcggcgc gtcggccccc gctattgatt accacagtca
    65761 gcagatggcg ctacccgcca gtacgcagaa agtgattact gcgctggcgg cgttgattca
    65821 actcggcccc gattttcgtt ttaccacgac gcttgaaacc aaaggcaatg tggaaaacgg
    65881 cgtacttaag ggtgacttag ttgcgcgatt tggtgccgat ccgacgttaa aacgtcagga
    65941 tattcgcaat atggtcacga ctttgaaaaa atctggcgtc aaccaaatcg atggcaatgt
    66001 gttgatagat acctccattt tcgccagcca cgataaagcc cccggctggc catggaatga
    66061 catgacacaa tgctttagcg caccgcctgc cgccgccata gttgaccgca actgtttctc
    66121 cgtctcgctc tacagtgccc caaaacctgg tgatatggct tttatacgcg tggcatctta
    66181 ttaccccgtt acgatgttca gccaggtacg caccctcccc cgtggttctg ccgaagcgca
    66241 atactgcgaa ctggatgtcg taccaggtga cctgaaccgc tttacgctaa cgggatgcct
    66301 gccacaacgt tctgagccgc tcccgttggc ttttgccgtg caggatggtg ccagctatgc
    66361 cggggcaatt ctgaaagatg agttaaaaca ggcgggtatc gcctggagcg gaacactgct
    66421 gcgccagact caggttaacg aacctggaac ggtagttgcc agtaaacagt cggccccgct
    66481 gcacgatctg cttaagatta tgctgaaaaa gtcggacaac atgattgccg atacggtttt
    66541 ccgcatgatc ggccatgcgc gcttcaatgt gcctggaaca tggcgggccg gatcggacgc
    66601 cgtgcgtcag atcctgcgcc agcaagccgg tgtcgatatc ggaaacacca ttattgccga
    66661 tggttcaggg ctttcgcggc ataacctgat tgcccccgcc accatgatgc aggtgctgca
    66721 atatattgcc caacacgaca atgaacttaa ctttatctcc atgctgccgc tggcgggcta
    66781 tgacggctct ttgcagtacc gtgcaggtct gcatcaggcg ggcgtggatg gaaaagtctc
    66841 agcgaaaacc ggttcgttgc agggggtata taacctggcg ggattcatta ccacagcgag
    66901 cgggcaacga atggcgtttg tgcaatatct ttctggctat gcagtagaac cggcggatca
    66961 gcgtaatcgc cgtattccgt tagtgcgttt tgaaagccgt ttgtataaag atatttatca
    67021 gaataattag cctaaagaga aaccccggca catggccggg gttttgctga ttaacgcttg
    67081 taaatgaact caacgccttc ttcgtcgtct tcgtcccagt cgtcatccca gtcctcatca
    67141 tcctcttcag caatctcttc aagctgctga cggtgataat catcccacat gaattcgact
    67201 ttctctggct gtttcgcttc ttcagcctgc acgaccgggt tttcaatgat aaaggtcatc
    67261 acatcccagc agagatcttt cacgcccagt ccgctcgccg cagagatcag ataatattta
    67321 tcttcccagc ccagcgcttc agcgatcgct ttcgctttct cttcggcttc tgccttatcc
    67381 agcagatcga tcttgttgaa aactaaccaa cgcggtttcg ccgccagatc ctggctgtat
    67441 ttttccagct cactgataat aatacgcgcg ttttcaaccg gatcggtgcc gtcaatcgga
    67501 tcgatatcga tgaggtgcaa caggacgcgg caacgttcca ggtgcttcag gaagcgaatg
    67561 cccagacctg cgccttctgc agcgccttca atcagccctg gaatatcggc aacaacgaag
    67621 ctcttttcgt tgtccattcg caccacgccc aggcttggta ccagagtggt aaacggataa
    67681 tccgccactt tcggtttagc cgccgataca gcacgaataa aggtcgattt acccgcgttt
    67741 ggcatcccca acataccgac gtcagccagc agcatcagct ccagcagcag ctcacgctta
    67801 tcgcccggcg taccgttagt tttctgccgt ggtgtacggt taactgacga tttgaaacga
    67861 gtgttgccca gaccgtgcca gccgccctta gcaaccagca gacgctgacc gtgtttggtc
    67921 atatcaccca tggtttcacc agtaccctgg tcgattacac gcgtacctac cggcacttta
    67981 atcgtgacgt ctttaccgcg cttacctgta cagtcgcggc ttgcaccgtt ttgaccgcgc
    68041 tctgcacgga aagatttttc aaaacgataa tcgataagcg tgttcaggtt ctcgtcggct
    68101 tccatccata cgtcaccacc gtcaccgccg tcgccgccat ccgggccgcc tttcggaata
    68161 tacttttcgc ggcggaagct cacgcaacca ttaccgccat cacctgcaac gaccagaatc
    68221 gatgcttcat caacaaactt cattttattc tccgtaaatc attcgcctgc gcggggttgc
    68281 gataccaccg ttgtatgctt acgtaatccg ccccaaatac gatgaccaat ggcggaatac
    68341 atcgcgcccg caaccacgac aaacgcaccg agataaccta aaaggtttaa catcggtctg
    68401 gcgaagaaat cgggccaggc cagtgataaa agatctgaaa aaaacagcgt aaacagtggg
    68461 gtgagcgtga tgatcgcgct cacctgcgct gcctgccagc gagccatcgc ttccgccagg
    68521 gcgccatatc ctaccaatgt attcagtccg caaaaaatta aacaggcgag ctgccagtgg
    68581 ctaagctgcg ctatcactcc aggatttgcc agagggaaga gcgcaattgt acataaagtg
    68641 tacagcaaaa acaggatctg cggtgaggcc agccgacgca ataaaacctt ttgcgccacg
    68701 ccataactca cccaaaccgt cgccgcaccg accccaaaga taactcccca ggtgtaatcg
    68761 gtgagctttg taaatatctc gaccagactg gtgttaaaaa acatcaccag gccgctcagg
    68821 agcatcaatg cccctacaac ctgagtactg cgcattttct ctttcaggat aaatacgctg
    68881 gcaaccatca tgccaactgg cgagagttgc ccaatcacct gcgaagcggt cggactcagg
    68941 tattgcaagg atgagctgaa caggatgaag ttcccaaaca gcccggcggt cgccactgct
    69001 aacaaaatca accagcgtgg cttacgaaac acgcgtaatg gcggcaaccg cttcttcacc
    69061 gcaagaatgg caccaaggcc aatactcgcc atcaagaaac ggtaaaacac gattgtcgga
    69121 ggttccatca cctccagcac ctgcttcatt gcgattggca acgcccccca gcaaattgct
    69181 gtggtgagcg ccaaaagaat gccaatgcct gcctgctgct tcataccgta ttccctgcaa
    69241 agcgcatatg cggattaacg tcgcaccatg cgcattttta ccggttatcg aatgtaaaaa
    69301 gccccgcaac gtgttgcggg gctttcatcc gttaccggga cgcgaaaaac ttattcagct
    69361 tcgatgctga taaatttacg gtttttcggg cctttaactt cgaatttcac tttaccgtct
    69421 gctttagcaa acagagtgtg gtcacgaccg caacctacgt tagcgccagc gtggaatttg
    69481 gtaccacgtt gacgaacgat gatgctaccc gccagaacgg attcaccacc gaaacgctta
    69541 acgcccaggc gtttagcttc tgaatcgcga ccgttacgtg tggagccgcc agccttttta
    69601 tgtgccattt gaaatctctc ctcaggtctt aggcgctgat gccagtaatt ttcacatcag
    69661 tgaaccactg acgatggccc tgctgcttac gatagtgttt acgacgacga aacttaacga
    69721 ttttaacttt ctcgccacga ccgtgagcaa caacttcagc tttgattacg ccgccatcaa
    69781 cgaaaggaac gccgattttg acttcttcac cgtttgcgat catcagcact tcagcgaact
    69841 caacagtttc gccagttgcg atgtccagct tttccaggcg aacggtctga ccttcgctta
    69901 ctcggtgttg tttaccacca ctttggaaaa ccgcgtacat ataaaactcc gcttccgcgc
    69961 acaccttttc aatgattcag agtgcgctat aaatattcac aatagggcgc gaatattacg
    70021 caaaacgcac gcctttgaca agtgctacag tcaatacacg aagaaaaaaa acacaacttg
    70081 tacggtaacg tttatctgtg ccattttttc agtacaatca ccctatattc ctaaccataa
    70141 accctaagtt gcctttgttc acagtaaggt aatcggggcg aaaagcccgg cttttgcgat
    70201 gaatttagaa aaaatcaatg agttaaccgc gcaagatatg gcgggtgtta atgcggcaat
    70261 ccttgagcag cttaattccg acgtccaact gatcaatcag ttaggctatt acatcgtcag
    70321 cggcggcggt aaacgtattc gtccgatgat tgctgtactg gctgcacgag ctgttggcta
    70381 tgagggaaat gcgcatgtca ccattgctgc cctgatcgag tttatccaca cggcgactct
    70441 gctacacgac gacgttgtgg atgaatcaga tatgcgcagg ggtaaagcta ccgccaacgc
    70501 cgcatttggc aatgccgcca gcgtgctggt aggcgatttt atttataccc gcgcgttcca
    70561 gatgatgacc agcctcggtt cactcaaagt gctggaagtc atgtcagaag ccgtaaacgt
    70621 catcgcagaa ggtgaagttc tgcaactgat gaacgttaac gatccggaca tcactgaaga
    70681 aaactacatg cgcgttatct acagcaagac tgcgcgtctg tttgaggctg ccgcgcagtg
    70741 ttccgggatt ctggctggct gtacgccgga ggaggagaaa ggcctacaag attatgggcg
    70801 ctatctcggc actgctttcc agttgatcga cgatttactc gattacaatg ccgatggcga
    70861 acagttaggt aaaaacgtcg gcgacgatct gaacgaaggt aaaccgacgc tgccgctgct
    70921 gcatgcgatg catcatggca caccagaaca ggcacagatg attcgtaccg ccatcgaaca
    70981 gggtaacggt cgccatcttc tggaaccggt tctggaagca atgaacgctt gtggatctct
    71041 tgaatggacg cgtcagcgtg ccgaggaaga agcagacaaa gccatcgcag cgttacaggt
    71101 gctcccggac accccgtgga gagaagcact tatcggcctc gcgcacatcg ctgttcaacg
    71161 cgatcgttaa tcccctcccc tcatcccgcg cagtgcgcgg gatgattcca gtaaattcca
    71221 taaaacactt attcagctct ataactcctg aaaaacaggg ctgtgtatct ttatatattc
    71281 tgaatattca cactctttac aggaactttt tagagcaata ggccatcagg agtatagtga
    71341 tgctcgacag aaacagaaga agtattctga atgaaagcga ctaatttaag gagtgaggaa
    71401 agatggaaag taatttcatt gactggcatc ccgctgacat cattgcaggt ttgcgcaaga
    71461 agggaacgtc aatggcggcg gagtctcgca gaaatggttt gagttcctca acgctggcga
    71521 acgcattatc acgcccatgg ccgaaaggag agatgattat tgcgaaagcc ctgggaactg
    71581 acccctgggt tatctggcca tcacgctacc atgatccgca gacccatgag tttatcgaca
    71641 gaacgcagtt gatgcgtagc tacactaaac cgaaaaaatg agtggtctgg cggtagcccc
    71701 gcgaacgggg ctgccagctc tcagacaatt actcgccttt cacacgctca atatttgcac
    71761 ctaaagcgcg tagtttgtct tcaatgcgtt cgtagccacg atcgatgtga taaatacgat
    71821 caaccaccgt cgtcccttcc gcaatacagc cagccagcac caggcttgct gatgcacgca
    71881 gatcggttgc cataacctgt gcgccagaaa gtttttcaac accgtgacaa ataacggtat
    71941 tgctttcgat ttcggcgtgc gcgcccatac ggctcagctc tggcacatgc ataaagcggt
    72001 tttcaaagac cgtttcggtg atgaatccgg tcccttctgc caccaggttc aacagcgtga
    72061 actgggcctg catatcggtc gggaatgccg gatgcggcgc ggtacgtacg ttaacagcct
    72121 tcggacgttt gccatgcata tccaggctaa tccagtcttc gccgacttcg atgtccgctc
    72181 cagcgtcacg cagtttcgcc agcacggcgt ccagagtatc tggctgcgcg ttacggcaga
    72241 taattttgcc gcgagagatc gccgccgcca ccaggaaagt accggtttcg atacgatccg
    72301 gcagcacgcg atagacaccg ccgcctaaac gttccacacc ttcgatgacg atacgatcgg
    72361 tgccctgacc gctaattttc gcacccagcg taatcaggaa gttcgcggta tcgacgattt
    72421 ccggttcacg cgctgcgttt tcaataatcg tggtgccttc cgccagggtt gcagcacaca
    72481 tgatggtcac cgttgcgcca acgctgactt tatccatcac gatatgtgcg cctttcagac
    72541 gaccatcgac ggaagcttta acgtaacctt cttccagttt gatggtcgcg cctaattgtt
    72601 cgaggccaga aatgtgtaga tcaaccggac gtgcgccgat cgtacaaccg ccaggcagtg
    72661 aaacttgccc ctgaccaaag cgcgctacca gcggccccag cgcccagata gaagcacgca
    72721 tggttttaac cagatcgtaa ggtgcgcaga atacattaac gtcgcgggca tcaatatgca
    72781 cagaaccatt acgttctact ttcgcaccca gctggcttag cagcttcatt gatgtatcga
    72841 cgtcttttag tttcgggacg ttctggatct ctaccggttc ttccgccagt agtgcggcaa
    72901 aaaggatagg cagagcagca tttttagcgc cggaaattgt gacttcgccc tggagcttcg
    72961 ttggcccctg aacacgaaat ttatccattt agtttgttct cagttaacaa ttcatatccg
    73021 ctaccggcga atcgcccata gctcaaaagc cgttcagttt gcgatcgcgc gcccactccg
    73081 caggggtata cgctttgatc gacacagcat gaatgcggtt atccgcaata tattccatca
    73141 gcgggccata gaccgtctgc tgttttttaa cccgactcat gccgtcaaac aactcaccca
    73201 cggcaataac ctgaaagtgg ctgccatcgc cggaaacgtg gacttcctgg agggagagag
    73261 cgttcatcaa cacgctctga atttcattat tttccatggg atcttcaatc atcagttaat
    73321 aaatcagcga aacatcttag agcaaagttg cgctggcata aataagcaaa aagcctcgct
    73381 gataaatcag acaaggctcg acttgcaggc aggtttgccg gacaggcggt taacgccata
    73441 tccggcctga aaaaatttaa cgaggcagaa catcagcagg caaattatac aatttcgcca
    73501 gggtatacac tttgtcgttt accccctgaa gcgtcacatt gttgccctgc tttttcgcca
    73561 gatcgataag atggagcagc agtgccagtc cacccgtatc cacgcgagac acacggctaa
    73621 gatcgatgct ggtaatcccc ttcaccgctt cctcacgtat ttcccaaagc ggtagcaaaa
    73681 cgtcctgatc cagctctccg gataacgcca gcgtgtcacc cgtctgcatc cagctcagtg
    73741 actcgctcat tattttttct cttccagagt gattttctgt tgagaaatcg atttcagttg
    73801 cgcagtcagg ccgtcgatac ctttggtacg cagcagcgtt ccccactcgt tttgtttggt
    73861 ggtgatcata ctgacgcctt cagcaatcat gtcgtaagcc tgccagttgc ccgtctggga
    73921 gtttttacgc cactggaagt ccagacgcac cggcgggcgg ccattcgggt caataatggt
    73981 aacgcgaatc ggcacaatgg ttttatcacc cagcggctgt tctggcgcaa tctgataggt
    74041 ttgaccgtga tacatcgcca gcgcctgacc gtaagcctgc ttcaggtact cacggaaagc
    74101 ggcaaagtaa gcatcacgtt gagctggggt cgcactcttg taatactggc ccagcaccag
    74161 cgcaccggcg tatttcacct gtacgtatgg caacagttcc tgatcaacaa tggtacgcag
    74221 ataatccggg ttggcccgaa tttgcggttg ctcattcttc aggcgatcga acgttttctg
    74281 cgccgcctcg tccatcagct tatacggatt ggtctggtct gccgcggttg ccgcactcag
    74341 cggtgcaatc accagcaaag cgaccatcat taaacgttta aacatgcgtc ggttctcctg
    74401 aaattatttc gttgtaccca caggttcagt ggtttcatta ttacctggcg cagcagctgg
    74461 cgcatcgcca ctattcttat tgtcatcgcc tttactaccg taaaggaact gaccaatgag
    74521 atcttccagc accatcgcag acttggtgtc ctgaattgta tcgccatcct tcaggatagc
    74581 agtccccagt tccgggtctt caaaaccgac gtttaatgcc agatattgtt cccccagcag
    74641 gccggaagta cgaatgctca gcgaactggt atcaggaatg tggttataac gttgttcaat
    74701 ttccagcgtt acgcgcggca gataggtttt cgggtccagc gtaatatccg ccacccggcc
    74761 cacaacaacg ccaccaatgc tgaccggaga gcgggctttc aggccgccaa tgttatcgaa
    74821 cgtcgcataa agcgtatagg tcggttcagt acgtatagac gtcacgttcg ctgccttcag
    74881 gcaaacaaac agcgccgcaa gcagtgctgc taataaaaag atacccaccc aaatttcatt
    74941 ttttttcgtt tgcatgaact caattcccaa acatcaatgc ggtcagcaca aaatccagcc
    75001 ccagaacagc cagagacgag tggacaacgg tgcgagtggt tgcccggcta atcccggcag
    75061 acgtcgggat ggcgtcgtag ccgttaaaca acgaaatcca cgtcaccgtg atggcgaaca
    75121 ccacgctctt aatcagacag ttgacgagat ccatacgcca gtcgacggca ttttgcattg
    75181 ccgaccagaa gaacccacta tcaatgcctt tccaactgac gccgaccagc gatccgcccc
    75241 agatccccac ggcgacgaag ataaccgtca acagtggtaa tgaaataact ccagcccaga
    75301 aacggggaga aataacccga cgcagcggat ccaccgccat catctccata ctggagagtt
    75361 gctctgtagc gcgcatcagg ccgatttctg cggttagcgc cgaaccagca cgcccggcaa
    75421 acaacaacgc ggcaaccacc ggccccagtt cacgcagtag cgataacgcc accagcatac
    75481 ccagactggt ttccgcacta taagtggtca gaaccagata accttgcagc cccaacacca
    75541 ttccgatgaa cacgccagaa acaacaataa tcagcatcga caggacgccg acattataga
    75601 gctggcgcac cagcagcggt gcatgtttgc gaaattccgg tttgccgacc agcgcattga
    75661 ataacattaa cccggcccgc ccgaacgttc tcagggtttt aatcccttta tgtccgagcg
    75721 acgccagcgc atttaacagc atgagtggct taactccctg gtaaaagatc agcgtgataa
    75781 tcgccggcag gatagcggaa cggaacaggc ccgtcagcta tcccgtccag aaactgacgt
    75841 acgcgcggat caggattcgc ctgcaacgcc tgggcactac catgagcgac aatttttttg
    75901 tccgccagga tccaggcgtg atccgcaata cttaacactt ccggcacatc gtgagaaacc
    75961 accacacaag tcacgcccag cgcgctgttc agctcagaaa tcagcttcac cagcacgccc
    76021 atggtaatgg gatcttgccc aacaaagggc tcatcaaaca tgatgagatc cggctccagc
    76081 gcaatcgcac gtgccagcgc tgcacgccgc gccatcccac cggaaagttc agaaggcata
    76141 agtttagccg ctccacgcag ccccacggcc tccagcttca tcatcaccgt actatgcaac
    76201 aatggcgcgg gaagttgggt atgttcccgc agtggatagg cgacgttgtc aaatacgttc
    76261 atatcagtga acaacgcccc ggactgaaat aacatgctca tccgtttgcg cactgtatac
    76321 aggcgcgaac gagacatcgc cggaatattc tcaccatcga aaagaatctc accatgatct
    76381 ggtgcgattt gcccgccaat cagacggagt agcgtcgttt taccgatgcc cgatggcccc
    76441 atgatcgccg tgatcttccc tcgcggcacg gtcagggaaa tattatcgaa gatgcagcga
    76501 ttgccacgcg taaaactgac atcgcgcata tcgactaaat tcgccacaga ctgctccata
    76561 attcaccctt cgtcttgcgt tgattttcta agcatggcgc tcaatttaac cttgaaccca
    76621 acatatttac agaatattac ctgccgtggt tagcgaaagc tggcatttgt tttacttttt
    76681 agccgcataa agtcaaaatt aagaatctgt tacggctttc tgaaaatctt cagcggaccg
    76741 gcgagtatac ctgaagaaag gacgttagat gcttttagct acggcactgt taattgttgg
    76801 tttacttttg gtcgtttaca gtgccgaccg cctggttttt gccgcgtcta ttctttgccg
    76861 aacctttggc atcccgccgt tgatcatcgg catgacggtg gtcagtattg gtacatcgtt
    76921 accagaaatc atcgtctcgc ttgccgcgtc tttgcacgaa caacgcgatt tagccgttgg
    76981 tacagccctc ggctcaaaca ttatcaatat attgctgatc ctcggtctgg ctgcgctggt
    77041 tcgtcctttt accgtccatt ctgatgttct acgccgtgaa ttacccttaa tgttgttggt
    77101 cagcgtggtg gccggttccg tactctatga cggacaactt agtcgcagcg atggtatctt
    77161 tctcctcttt ctggctgtgc tatggctgct gttcattgtt aaacttgcac gtcaggctga
    77221 acgtcagggg actgacagcc tgaccagaga gcagcttgca gagctgccgc gtgaaggtgg
    77281 attgcccgtc gcatttttat ggctcggcat cgcactgatc attatgccag tggccacgcg
    77341 gatggtagtt gataacgcca cggtgctggc gaattacttt gccatcagcg agttgacgat
    77401 gggtctgacg gcaattgcta tcggaaccag cctgccggaa ctggcaaccg caatagcagg
    77461 ggttcgcaaa ggtgaaaacg acattgcggt cggaaatatc attggcgcaa acatttttaa
    77521 tattgtcatc gtgttgggtt tacccgcgct gataacgcca ggagagattg atccactggc
    77581 gtacagtcgt gactacagcg tgatgttgct ggtgagcatt atttttgcgt tgctgtgctg
    77641 gcggcgctcc ccgcaaccgg gccgtggtgt aggggtatta ttaactggcg gatttatcgt
    77701 atggctggcg atgttgtact ggttatcgcc aatactcgtt gaataactgg aaacgcatta
    77761 tgtcgcacgt agagttacaa ccgggttttg actttcagca agcaggtaaa gaagtcctgg
    77821 cgattgaacg tgaatgcctg gcggagcttg atcaatacat caatcagaat ttcacgcttg
    77881 cctgtgaaaa gatgttctgg tgtaaaggga aagttgtcgt catggggatg gggaaatcgg
    77941 ggcacatcgg gcgcaaaatg gcagcaacat ttgccagcac tggtacacct tcatttttcg
    78001 tccatcctgg tgaagccgcg catggtgatt taggcatggt caccccgcag gatgtggtga
    78061 ttgctatctc taactcaggt gaatccagcg aaatcacggc cttaattcca gtgcttaagc
    78121 gtcttcacgt accgttaatc tgcatcaccg gtcgcccgga gagcagcatg gcgcgcgccg
    78181 cagatgtgca tctgtgtgtt aaagtagcga aagaagcctg tccgttaggg ctggcaccga
    78241 ccagcagcac aaccgccacg ctggttatgg gcgatgccct cgctgtcgcg ctgttaaaag
    78301 cacgcggctt tactgctgaa gattttgcgc tctcacaccc aggcggcgca ctgggtcgta
    78361 aacttctgct gcgcgtaaac gatattatgc atacgggcga tgagatcccg catgttaaga
    78421 aaacggccag tctgcgtgac gcattgctgg aagttacccg caaaaatctt ggtatgactg
    78481 tcatttgcga tgacaatatg atgattgaag gcatctttac cgacggtgat ttacgccgtg
    78541 tcttcgatat gggcgtggat gttcgtcagt taagtattgc cgatgtgatg acgccggggg
    78601 gaatacgcgt gcgcccaggc attctggccg ttgaggcact gaacttaatg cagtcccgcc
    78661 atatcacctc cgtgatggtt gccgatggcg accatttact cggtgtgtta catatgcatg
    78721 atttactgcg tgcaggcgta gtgtaaagat tcaaggataa acaacaatga gcaaagcagg
    78781 tgcgtcgctt gcgacctgtt acggccctgt cagcgccgac gttatggcaa aagcagagaa
    78841 cattcgtctg ctgatcctcg acgttgacgg cgtactgtca gatggcctga tttatatggg
    78901 caataacggc gaagagctga aagcgttcaa tgttcgtgac ggttatggca ttcgttgtgc
    78961 gctcacctct gatattgaag tcgctatcat taccgggcga aaggctaaac tggtagaaga
    79021 tcgttgtgcc acattgggga tcactcactt gtatcagggg cagtcaaaca aactgatcgc
    79081 ctttagcgat ctgctggaaa aactggcgat tgccccggaa aatgtggctt atgtcggcga
    79141 tgatctcatc gactggccgg taatggaaaa agtgggttta agcgtcgccg tggccgatgc
    79201 gcatccactg ttgatcccgc gcgccgatta cgtaacgcgc attgctggcg gtcgtggcgc
    79261 agtgcgagaa gtttgcgact tattactcct ggcgcagggc aaactggatg aagccaaagg
    79321 gcaatcgata tgagtaaagc cagacgttgg gttatcattg tgctatcact ggcggttctg
    79381 gtgatgatcg gcattaatat ggccgaaaaa gacgataccg cccaggtggt cgtcaacaac
    79441 aatgatccca cctataaaag cgagcatacg gacacgctcg tctataaccc agaaggggca
    79501 ctaagctatc gattgattgc tcaacacgtt gaatattatt ccgatcaggc cgtttcgtgg
    79561 tttacgcagc cggtacttac cacgtttgat aaggataaaa tcccgacatg gtccgtaaaa
    79621 gcagataaag ccaagctgac caatgaccgg atgctctatt tatatggaca cgttgaagtc
    79681 aatgcactcg tgccggactc tcaacttcgc agaatcacga cggataacgc gcagatcaat
    79741 ctggtgacgc aggatgttac ctctgaagac ctcgtcacgt tatacggaac aacatttaac
    79801 tccagcggtc tgaaaatgcg cggcaactta cgcagcaaga acgccgagct gattgaaaag
    79861 gttagaacat cctatgaaat tcaaaacaaa caaactcagc cttaatcttg tgcttgccag
    79921 ctcacttctg gccgccagca ttccggcatt tgccgtaacc ggagacactg atcagccgat
    79981 ccacattgaa tcggaccagc aatctcttga tatgcaaggc aacgtggtta cctttaccgg
    80041 taatgttatc gtcacccagg gcaccatcaa aattaatgcc gacaaagtgg tcgttacccg
    80101 tccgggcggc gaacaaggta aagaagtgat tgacggctac ggtaaaccgg caacgttcta
    80161 ccagatgcag gacaacggta aacccgttga aggtcacgct tcccagatgc actacgaact
    80221 ggcaaaagat tttgtcgttc tgacgggtaa tgcttatctg cagcaggtcg atagcaacat
    80281 taagggcgat aagatcactt acctggtgaa agagcagaaa atgcaggctt tcagcgacaa
    80341 aggcaagcgc gtaaccaccg ttctggtgcc gtcgcagttg caggacaaaa acaataaagg
    80401 ccagaccccg gcacagaaga agggtaatta attcgttatg gcaacattaa ctgcaaagaa
    80461 ccttgcaaaa gcctataaag gccgtcgcgt ggtagaagac gtcagcctga ccgtcaactc
    80521 cggggaaatt gtcggtctgc tggggccaaa cggtgccggt aagaccacca ctttctacat
    80581 ggttgttggc attgtgccgc gcgatgcggg caacatcatt attgatgatg acgatatcag
    80641 tctgctgcct ctgcatgcac gcgcgcgccg cggtatcggc tatctgccgc aggaagcctc
    80701 cattttccgt cgcctcagcg tttacgataa cctgatggcg gtactgcaaa ttcgtgacga
    80761 cttgtctgct gaacaacgtg aagaccgtgc gaacgagctg atggaagagt ttcacattga
    80821 gcacctgcgt gacagcatgg ggcagtcact ctccgggggt gaacgtcgcc gtgtagaaat
    80881 tgcccgcgca ctggctgcga atccgaaatt tattctgctc gacgaaccgt ttgccggggt
    80941 tgacccgatc tcggttatcg acattaaacg catcattgag cacctgcgcg acagcggcct
    81001 gggcgtactg atcactgacc acaacgtgcg tgaaacactg gcggtttgtg aacgcgctta
    81061 tatcgtcagt caggggcatt tgatcgccca cggcacgcct acagaaatct tacaagacga
    81121 acacgttaag cgtgtatacc ttggggaaga cttcagactc tgatagggta gaagtttgcg
    81181 acgttttagc aggagagtac gattctgaac atgaagcaag gtttgcaact caggcttagc
    81241 caacaactgg cgatgacgcc acagctccaa caggcaattc gtctgttgca gttgtcgacg
    81301 ctggaacttc agcaagagct acagcaggcg ctggagagca atccgctgct tgagcaaatc
    81361 gacactcatg aagaaatcga cacccgcgaa acgcaagaca gtgaaacact ggacaccgcc
    81421 gacgcgctcg aacaaaaaga gatgccggaa gagctgccgc tcgatgccag ttgggacacc
    81481 atttacaccg ctggtacacc atccggcacc agcggtgact acattgatga cgagctgccg
    81541 gtctatcagg gcgaaacgac gcagacctta caggattacc tgatgtggca ggtcgagttg
    81601 acaccgtttt ccgacactga ccgcgcgatt gctacctcta tcgtcgatgc cgttgatgac
    81661 accggttatc tgactgtccc gctggaagat attctcgaaa gtatgggcga tgaagagatt
    81721 gacatcgacg aagttgaagc cgtccttaag cggatccaac ggtttgatcc agtcggtgtg
    81781 gcggcaaaag atctgcgtga ctgcctgctg atccaactct cccaattcga taagaccacg
    81841 ccatggctgg aagaggccag actgatcatt agcgatcatc tcgatctatt agccaatcac
    81901 gacttccgca ctttaatgcg cgtcacgcgt ctgaaagaag atgtgctgaa agaagccgtc
    81961 aatctgatcc agtcgctcga tccgcgcccc gggcagtcga tccagactgg cgaacctgag
    82021 tatgtcattc cagatgtgct ggtgcgtaag cataacggcc actggacggt agaactcaac
    82081 agtgacagca ttccgcgtct gcaaatcaac cagcactacg cctcgatgtg caataacgcg
    82141 cgcaatgatg gtgatagcca gtttatccgc agcaatctgc aggatgccaa atggttgatc
    82201 aagagtctgg aaagccgtaa cgatacgcta ctgcgcgtga gtcgctgtat cgttgaacag
    82261 cagcaagcct tctttgagca aggtgaagaa tatatgaaac cgatggtact ggccgatatc
    82321 gcccaggctg tcgaaatgca tgaatcgacg atatctcgcg tgaccacgca aaaatacctg
    82381 catagtccac gaggcatttt tgaactgaaa tatttctttt ccagtcacgt caatactgaa
    82441 ggcgggggtg aagcctcttc cacagcgatt cgtgcgctgg tgaagaaatt aatcgcggcg
    82501 gaaaacccag cgaaaccgtt gagcgacagc aagttaacct ctttgctgtc ggaacaaggt
    82561 atcatggtgg cacgccgcac tgttgcgaag taccgagagt ctttatccat tccgccgtca
    82621 aaccagcgta aacagctcgt ttgacccaac cgataaggaa gacactatgc agctcaacat
    82681 taccggaaat aacgtcgaga tcaccgaggc actgcgcgaa tttgttacag ccaaatttgc
    82741 caaacttgag caatattttg accgaatcaa ccaggtctat gttgttctga aagtggagaa
    82801 agtcacccac acctcagatg caacactgca tgtaaacggt ggtgaaattc atgccagcgc
    82861 ggaaggtcag gacatgtacg ctgccattga tggcttaatt gataagctgg cacgccagtt
    82921 gaccaaacat aaagataaac tgaaacaaca ctaattgtcc gggcaattag catgtgcatg
    82981 gcggcctgtt gtgcggcaca acgggccatt tgtacggtta atgctccgaa cctgttccac
    83041 tgtttgagtg ggcaggttct taggtgaaat tatgacaaat aatgatacaa ctctacagct
    83101 tagcagtgtt cttaacaggg aatgtacgcg aagccgcgtc cactgccaga gcaaaaaacg
    83161 cgccctggaa atcatcagcg agctggcggc gaaacaactt agcctggcgc ctcaggtggt
    83221 ttttgaagct atcctgacgc gggaaaaaat gggcagtacc ggtatcggca atggtattgc
    83281 cattccgcat ggcaaactgg aagaagatac tctgcgtgcc gttggcgttt tcgttcagct
    83341 cgaaacacct atagctttcg atgccatcga caaccaaccg gtggacttac tttttgccct
    83401 gctggtgccg gcagaccaaa ctaaaacgca cctgcatact ctgtcgctgg tggcgaaacg
    83461 tctggcggac aaaaccatct gccgccgttt acgcgcagcc cagagcgatg aagagctgta
    83521 tcaaatcatt acggataccg aaggtactcc ggatgaagcg tagttattcg gtaatgtctc
    83581 ttttagacgt tgtgaggaga aacagtacat ggtactgatg atcgtcagcg gacgttcagg
    83641 ttcaggtaaa tctgtcgccc tgcgtgcgct ggaagatatg ggtttttact gcgtggataa
    83701 ccttcccgta gtgttgttac ccgatctggc tcgaactctg gccgatcgag agatttctgc
    83761 cgccgtcagc attgatgttc gtaatatgcc ggagtcacca gaaatattcg aacaggcgat
    83821 gagtaacctg cctgacgctt tctcaccgca actactgttc ctggatgccg accgtaatac
    83881 cttaattcgt cgttacagtg acacgcgccg actgcatccg ctttccagca aaaacctgtc
    83941 gctggaaagt gctatcgaca aagaaagcga tttgctggag cctctgcgtt cgcgagcgga
    84001 tctgattgtc gatacctcag aaatgtccgt tcacgagctg gcagaaatgc tgcgtacccg
    84061 tctgttgggt aaacgtgaac gtgaactgac catggtcttt gagtctttcg gcttcaaaca
    84121 cggtatccct atcgatgcag attacgtctt tgacgtgcgc ttcttgccga acccacactg
    84181 ggatccgaaa ctgcgtccaa tgacaggtct tgataaacct gtcgccgcgt tcctcgaccg
    84241 ccacacagaa gtacacaatt ttatctacca gacgcgaagc tatcttgagc tatggttacc
    84301 tatgctggaa accaacaacc gtagctacct gacggtcgcc attggttgta ccggcgggaa
    84361 gcaccgttcg gtgtatattg cagagcaact ggcagactac ttccgctcgc gcggtaaaaa
    84421 cgtccagtca cgccatcgga cgctggaaaa acgtaaacca tgaccgtcaa gcaaactgtt
    84481 gaaattacaa acaagctggg catgcatgcc cggcctgcaa tgaagctgtt tgaattaatg
    84541 cagggttttg acgctgaagt gctgttacgt aatgacgaag gcaccgaggc tgaagccaac
    84601 agcgttattg cgctgctgat gttggattct gccaaaggac ggcagattga agttgaagcg
    84661 accggtccac aggaagagga agcactggcc gccgttatcg ccctctttaa ctctggtttt
    84721 gatgaagatt aatcttcatc actttgacat tcaaatccct tcaagctccc ccggcaataa
    84781 gaaaagcgcg tactgaaatc gttatcaatc aacgtcgatt gtacatttcg tgcgcttttt
    84841 actttcagaa gaaccttaag aaaaccttaa gaagcattgt ttagatttcg tttaagttaa
    84901 tcgaccatac tggagatcgt cagaaaatat ttccaggaga tggcatgatt cgcttatctg
    84961 aacaaagtcc cctgggcacc ggaagacatc ggaaatgtta tgcgcatccg gaagatgccc
    85021 aacgctgtat caagattgtc taccatcgtg gcgatggtgg cgataaagag atccgccgtg
    85081 agttaaagta ctacgcgcat cttggtcgcc ggttaaaaga ctggagtgga ataccgcgct
    85141 atcacggtac cgttgagacg gattgcggaa ccggttatgt ctacgatgtg attgccgatt
    85201 tcgacggcaa gccttccatt acgctgaccg aatttgcaga acaatgccgt tacgaagaag
    85261 acattgcaca actgcgccag ttactgaaac agctgaagcg ttatttgcag gataaccgta
    85321 tcgtgacgat gtcgctgaag ccgcagaata tcctctgtca ccgcatcagt gagtcagagg
    85381 ttatccccgt cgtctgcgac aacattggtg aaagcacatt gattccactg gcgacctggt
    85441 cgaagtggtg ttgtctgcgt aagcaagagc ggttatggaa acgatttatc gcccaaccgg
    85501 cgctggctat tgccctgcag aaagatctgc aacctcgtga gagcaaaacg ctggccctca
    85561 cttcgcgcga agcttaatca agctggtgtt gttgcataaa cggctcaccg cctaactgat
    85621 acatctgccg taaaatccac gcctgacggc tacgcacata gcccgatggc gcggagactt
    85681 tgaaacgaag tggattaggt aatacagctg ccagtaatgc agcttccgac cgggtaagtt
    85741 tgctcgcggg tttgtggaaa taacgttgtg ccgcagcttc gacgccaaac acaccgtcgc
    85801 caaattcggc gatattcagg taaaccgtca ggatacgctt tttgctccag actgtttcta
    85861 tccccagcgt taatccggct tccagccctt ttcgaaccca gctacgccca tcccataaaa
    85921 agagattttt ggctgtctgc tgagaaatcg ttgaagcacc gcgaatacgg ttttcattgc
    85981 gctcgttgtg cgccagggct tgctcaatgg aagcgacatc aaagccccag tgctcaggaa
    86041 atttctgatc ttctgcggca atcaccgcca gtcccatcca cggcgagatt tgatccatac
    86101 tgacccagtc agaatgtgcc acgtaacgaa aattgccatg cagccaggcg ctgacttgcc
    86161 gctcgaccat taccgctgag aaaggaacag gcgcaacgct aaacaacgcg atgcccccgc
    86221 cccagaaaat ggcgaggaca accattaacc gcagaagaaa acggcgaacg aaactaaaca
    86281 ccgttaagcg gcttttactc attcagccag aaccagcacg cgggaaacca gcttatcaat
    86341 gccgctcgcc gcttctgcaa tgttctgcgc cagcatatat gccggggtgg tgacaatctt
    86401 attgtcttca tcaaccacga tatcatcgac aggacacggc acatgctccg cgcccatctc
    86461 ttccagcact tctgcggtat cgatatcagt accgatggtc aaacgtagcg ggaaatcgaa
    86521 aattttcggc agtatcgccg gtgcaataca cataaaacca agcggttttc cggcctgatg
    86581 catcgcttgt gccagcgcct ttaattcacg gtcaacggtg cattcgctac caagactggc
    86641 aaaattgctt aaattcttcg ccgcgccaaa accccccggc acaatcaacg catccagttc
    86701 agcggcatcg gcctgggcca gaggacggat ttcaccgcgc gttattcgtg ccgcttcaat
    86761 cagcacattg cgcgtttccg tcatcgcttc accagttaaa tggttgataa catcaacctg
    86821 ctgcttatcc ggtgcaaagc aaaccgcctg cgcaccgctg cgtgaaatag ctaacaacgt
    86881 caataccgct tcatgaattt cagaaccgtc atagacgccg catccgctca gaattacgcc
    86941 aattttcttc attgtgatct tcctttcgca attgactgaa acacattaat ttttttaata
    87001 aaaatgctac gcatcacaca tttaactgat tcatgtaaca aatcatttaa gttttgctat
    87061 cttaactgcg tgcggcctga aaaacagtgc tgtgcccttg taactcatca taataattta
    87121 cggcgcagcc aagatttccc tggtgttggc gcagtattcg cgcaccccgg tctagccggg
    87181 gtcatttttt agtggctttt gccacccacg ctttcagtac ttctacgtcg tgacgccact
    87241 cttctttcat ctcttcaatc cattcaccga cgttatcttc ccaggcggga aggtcaggag
    87301 actgaatttg ctgacccagc tgttgcagat ggcgtaaccc cactgacccc gccgcacctt
    87361 taattttatg cccttcctca acaatgcctt ttttatcctg cgccgtcaga ttcgactcca
    87421 gcacgctgac atagcccggc atcattctct caaacaccgc taacccgtcg gtgatcagct
    87481 tcggtcctac aagttcgaga tactgttcca gcatgggaat atcgagcaat gcttctgatt
    87541 tactgttctc ttctgtcgtc accgtactct cctcatcatc ctgggtatcc cagaatttct
    87601 tgatcatcgc ggttagcgcc ggaacagaaa gcggcttact cagcacatca tccattccag
    87661 cattgaggta ctcttgcttg tctttcagca cgttagcggt taaggccacc agcggcggta
    87721 aatcctcgcg cggataacgc ttcgtcagtt cacgagagat atccagcccg gtcatatctg
    87781 gcaactgaat atccagcaat accaggtcgt attcgcccgg tttaaacatc tccagcgccg
    87841 ccttgccggt catggcgaca tcaacgctgt tacctaattt ttccagcaca gaacgcgcga
    87901 caatcacgtt cagttcaatg tcttccacca gcagcacatt cagcgccggt aaaggcatat
    87961 cgtcttcatc aaacgcatca tcaacctctt ctgctaccga cggtgcgtgg atcgtcaacg
    88021 taaaggttga acctttgccc tgttcgctgg taaccgtaat atcgccgccc atatttttcg
    88081 ccagacgacg agaaacggcc agaccaatac cggtgccggt ggcaggttta ccgccatgac
    88141 tgtctttcac ctggtaatac atggcgaaga ttttatccag ctcatcctgc ggaatgccga
    88201 taccagagtc ttccacttca aaatgcagca tatcgccttc atcgtagcgc acgcgcacgg
    88261 taacctggcc ttgctgagtg aatttgacgg cgttactgat gaggttccac aagatctgcc
    88321 gtaaacgcgt cccgtcggta atgacctgat gcggtaatgg cagcgtcggc tccagattaa
    88381 agcgcaatcc tttttgttgc gcctgcaatg cggagagatt ttccagatcg gcaaggaagc
    88441 tggtgaaatc aaccggctga ttatcaagct ggaccttgcg ccgttccatc ttatccatgt
    88501 cgataatatc gttgaagata ttccccagcg tgacagccga aacatggatg gttttgagat
    88561 atttttcctg ctcggcggtg agttcagtat ccagcagaat gcggctcagg ccgacgatac
    88621 cgttcagcgg tgtacgcaat tcgtgactga tggtggagat aaacgtcgtt ttgtcgcggc
    88681 tggcgcgttc aagcgcatcc tgataccgct tacgctcggt aatgtcgcga ccaaagccca
    88741 tcaaaccgtg acgtttaccc acgcggtcgt agtacggcac tttacggatt tcaaagcagg
    88801 ctttgcgtcc gtcgggataa tccagccact gctcataggt cagtgacaca ttatgacgga
    88861 acactttttc atcggtttca atgactttcg cagcggcttc tggtgagtaa acatcagcag
    88921 gtttcaggtg aaccagttgt ttttcgcttt ttccggtcag cagctccatc gcgcggttac
    88981 agccggaaaa ctctttatct tcgttacgat aaaaaaccag gtcgggtgaa gcgtcaagga
    89041 aggaacgtaa gaatgaggat tgctgctcga gctgaatttg tgtctcttcg cgctctttga
    89101 tttcaatttt cagttggccg aaggtttcct gcagttctgc ttccgctttt tcacgaacgg
    89161 cgatttcctg atttagctgg gcaatattat cttttaactg aacgttgagg ctcaaatcgc
    89221 gctcgcgcat ctcctccagt ttttgcacca gtcgtgacag acgttgtcgt gactcctcca
    89281 gttgctcgac gaccaccgat agaaagtaga ccgcccacgg cgtaatcagc aaaccaaaga
    89341 agatagaacg aataacatca atgctttcga cctgaccatg cagcaccatg gttaccgcca
    89401 tttgtaccac aatggcaaga acgacgaggg ccagcgccag caacattgag aagcgcacca
    89461 gacctaactt catcatcagg tcaacataat actgcgccag cagacgaatt tgcttcatta
    89521 gggaattcct tcacgacaac ctgccccaat aatacccaat tctgacagtt acgttataaa
    89581 ttgtgtgaga aatgcggaat tcccctcaat ggcctacgcc gttggaggta gccacggacg
    89641 tcccagcgcc gatccctgta cgccatgttc attcagataa cgatccagct cgaccattcc
    89701 cgtccatcga ttttcgcacc acagcggagc aagcagcgtc gggcgacggg cgctggcgga
    89761 aatacggtgg tagataactt ccggtggcgt atggcgaatc atttctccgg cagtgagcgt
    89821 gtaatcctcc agttcaattc cgttcaaacg ccccgcttcc caggctttcg ccataatgct
    89881 gcctttcact atatgcagcg gatgcagctt tatgccgtcc acgccggttt caaccactcg
    89941 ctccagcgtt tgcaaacatt cagcctgccc ttcgccaggc aggccaacaa ttaagtgaga
    90001 gcacaccttc agcccacgct cacgcgccag ctgcgtcgtg cgctgatagc aggcaaaatc
    90061 atgaccgcga tttatgcgat gcagtgtttt gtcgtgggcg gtttgtagcc ccagctccag
    90121 ccacacttcg tagccctggt ccttatattc gcaaagcaga tccagcaccg catccggcac
    90181 gcagtccggg cgggtaccaa cacacaaacc gacaatattg gcctggctca ccgcctgctg
    90241 atacatcgaa cgcagcacct gaacttccgc aaaggtgctg gtatacgcct gaaagtaggc
    90301 cagatagcgt ttagcgcggt taactaaatt cgcctggtgc gccagttgct cggcaatgga
    90361 acgatgctgc tgcgcttcat cggcaaacga ggcaacatta cagaatgtgc agccgccacg
    90421 cccgatggta ccgtcacggt tagggcagct aaaaccgccg tgcagcgtca gcttatgcac
    90481 cttttgccca taacgacggg tgagatcacc accaaacata ttgactaatt tctgtaactg
    90541 cataatctga tagaccgcgc cttgaaaaga ggccaaagcc tgccattttt agcccaattc
    90601 ggcgatgacc tggatcaatc gtcccagcct gcttttatca actgcataac caatcaaaat
    90661 taccgaaatt tcatgcacaa tcacataaat cactgttgct tatcttgtgt cagatttttt
    90721 tatcttctta tggattttag gcaaaaacag tagcatgaaa cgttattacc aattaaggca
    90781 gtataaaatg ctggctttct catcaattca aggcaggata agggttaaca cgcctttatg
    90841 acagtcagga attggctgtt tctctaacga cacccctttt agccttaaat agaaaatcca
    90901 ctttaatttc atacaattaa taaagaattt tgcgctaaag cacatttctg taccaataag
    90961 cttgccattt gacctgtatc agctttcccg ataagttgga aatccgctgg aagctttctg
    91021 gatgagcagc ctgctcatca tatttatgca gtaattgaga tcccctcttc accgtattaa
    91081 ccgatgcgaa aaggacaaca agggggcgaa tgcgaggtgc gcgtatgaca cgcaaacccc
    91141 gtcgccacgc tcttactgtg cccgtgcgca gcggttcgga agtggggttc ccgcagagcc
    91201 tgggggaggt tcacgatatg ttgtacgata aatcccttga gagggataac tgtggtttcg
    91261 gcctgatcgc ccacatagaa ggcgaaccta gccacaaggt agtgcgtact gcaatacacg
    91321 cactggcccg catgcagcac cgtggcgcga ttctcgccga tggtaaaacc ggtgacggtt
    91381 gcggcttgct gttacaaaaa ccggatcgtt tttttcgcat cgttgcgcag gagcgcggct
    91441 ggcgtttagc aaaaaactac gccgtcggga tgctcttcct gaataaagat cctgaactcg
    91501 ccgctgccgc acgccgcatc gttgaagaag agctgcaacg cgaaacgttg tcgattgtgg
    91561 gctggcgtga tgtccccact aacgaaggcg tgctgggtga aatcgccctc tcctctctgc
    91621 cacgcattga gcaaattttt gtgaacgccc cggcaggctg gcgtccgcgc gatatggagc
    91681 gccgtctgtt tatcgcccgc cgccgcattg aaaagcgtct cgaagccgac aaagacttct
    91741 acgtctgtag cctgtcgaat ctggtcaata tttataaagg tctgtgtatg ccggcggatc
    91801 tgccgcgctt ctacctggac ctcgcggacc tgcgtctgga atcggccatc tgcctgtttc
    91861 accagcgctt ttccactaac accgtaccgc gctggccgct ggcgcagccg ttccgctacc
    91921 tcgcgcataa cggtgaaatc aacaccatca ctggtaaccg ccaatgggcg cgtgcgcgta
    91981 cctataaatt ccagacgccg ctgatccctg acctgcacga cgccgcgccg ttcgtcaacg
    92041 aaaccggctc tgactccagt tcgatggata acatgctgga actcctgctg gcaggtggga
    92101 tggatatcat ccgtgccatg cgtctgttag tgccacctgc ctggcagaac aacccggata
    92161 tggacccgga actgcgtgcc ttctttgact ttaactccat gcatatggag ccgtgggatg
    92221 gcccggcagg catcgtgatg tctgacggtc gttttgccgc ctgtaacctc gaccgtaacg
    92281 gtctgcgtcc ggcgcgctac gtcatcacca aagataagct cattacctgc gcctctgaag
    92341 tcggtatctg ggattatcag cctgacgaag tggtcgaaaa aggccgcgtg gggccaggcg
    92401 aactgatggt tatcgacacc cgcagtgggc gtattctgca ctcggcagaa accgatgacg
    92461 atctgaaaag ccgccaccct tataaagagt ggatggagaa aaacgtccgc cgtctggtac
    92521 cgtttgaaga tctgcccgat gaagaagtgg gtagccgcga actggacgac gacacgcttg
    92581 ccagctacca gaaacaattt aactacagcg cggaagagct ggattcggtg atccgcgtac
    92641 tgggtgaaaa cggtcaggaa gcggtcggtt cgatgggcga cgatacccca ttcgccgtgc
    92701 tctccagcca gccgcgcatt atttacgact acttccgcca gcagtttgct caggtaacca
    92761 acccgccaat cgacccgctg cgcgaagcgc atgttatgtc gctcgccacc agtatcggtc
    92821 gtgaaatgaa cgtcttctgt gaagcagaag gccaggcgca ccgtttaagc tttaaatcgc
    92881 cgattctgct ctattccgat ttcaaacagc tcacgacgat gaaagaggat cactaccgcg
    92941 cagatacgct ggatatcacc tttgacgtca ctaaaaccac gctcgaagcg acggtgaaag
    93001 aactgtgtga caaagccgaa aaaatggtac gtagcggcac cgtgctgctg gtgctctccg
    93061 accggaatat cgctaaagat cgcctgccgg ttccggctcc gatggcggtt ggcgcgatcc
    93121 agacccgtct ggtcgagcaa agcctgcgtt gcgatgccaa catcatcgta gaaaccgcca
    93181 gcgcccgtga tccgcaccac ttcgccgtgt tgctgggttt cggcgcgacg gctatttatc
    93241 cataccttgc ctatgaaacg ctgggccgcc tggtagacac ccacgcgatt gccaaagatt
    93301 atcgtaccgt gatgctcaac tatcgtaacg gcatcaacaa aggcttgtac aaaatcatgt
    93361 ccaaaatggg catctccacc atcgcctctt accgctgctc gaaactgttt gaagcggtcg
    93421 gtctgcacga tgatgtcgtg ggcctgtgct tccagggggc agttagccgc attggggggg
    93481 cgagctttga agacttccag caggatctgc tgaatctgtc gaaacgagcc tggctggcgc
    93541 gtaagcctat cagccagggc ggcctgctga aatatgtaca cggtggcgaa taccacgcct
    93601 acaacccgga cgtggtgcgc acgctgcaac aggcggtaca gagcggcgag tatagcgact
    93661 atcaggaata cgcgaagctg gttaatgagc gtccggcaac cacgctacgc gatctgctgg
    93721 caattacgcc gggtgaaaac gcggtcaaca ttgctgatgt tgaaccggca agcgaactgt
    93781 ttaaacgctt cgataccgcc gcgatgtcta tcggtgcgtt aagcccggaa gcccacgagg
    93841 cgctggcgga agcgatgaac agcatcggcg gtaactcaaa ctccggcgaa ggcggtgaag
    93901 acccggcgcg ctatggcact aacaaagtgt cgcgcatcaa gcaggtagcg tccggtcgct
    93961 ttggggttac tccggcgtat ctggtcaatg ccgacgtcat tcagataaaa gtcgcccagg
    94021 gcgcgaagcc gggtgaaggt ggtcagttac cgggtgataa agtcactcct tacattgcca
    94081 aactgcgcta ttcggtgccg ggcgtgacgc tgatctcccc gccgccgcac cacgatatct
    94141 actctattga ggatttagcg cagctgattt tcgacctcaa gcaggtcaat ccaaaagcga
    94201 tgatctccgt gaagctggtt tccgaaccgg gcgtaggcac catcgcgact ggcgtggcaa
    94261 aagcttatgc cgatttaatc accatcgcag gctatgacgg cggcaccggc gcaagtccgc
    94321 tttcatcggt gaaatacgca ggctgtccgt gggagctggg gcttgttgaa acccaacagg
    94381 cgctggttgc caacggcttg cgtcacaaga tccgtttgca ggtcgatggc ggcctgaaaa
    94441 cgggtgtcga tatcatcaaa gcggcgattc ttggcgcgga aagttttggc ttcggcactg
    94501 gcccgatggt agcgcttggc tgtaaatatc tgcgaatttg ccacctgaac aactgcgcca
    94561 cgggtgtagc aactcaggat gacaaactgc gtaagaatca ctatcacggc ctgccgttca
    94621 aagtgactaa ttactttgag tttatcgccc gtgaaacccg cgagctgatg gcacagctgg
    94681 gggtaacgcg tctggtggat ctgattggtc gcaccgacct gctgaaagag ctggacggtt
    94741 tcaccgccaa acagcagaaa ctggcactgt cgaagctgct ggagactgcc gagccgcatc
    94801 ctggtaaagc gctctactgc accgaaaaca acccgccgtt tgataacggc ctgctgaacg
    94861 cgcagttgct gcaacaggca aaaccgtttg tcgatgaacg ccagagcaaa accttctggt
    94921 tcgatatccg caacaccgac cgttctgtcg gcgcgtcgct ttcaggctat atcgcccaga
    94981 cgcacggcga tcaggggctg gcagccgatc ctatcaaagc gtacttcaac ggcactgcag
    95041 gccagagctt cggcgtgtgg aacgcgggcg gcgtggaact gtacctgacc ggtgatgcca
    95101 acgactatgt tggtaaaggc atggcgggcg gcttaatcgc cattcgtcct ccggttggtt
    95161 ccgccttccg cagccatgaa gcgagcatta tcggcaacac ctgcctgtat ggcgcgaccg
    95221 gtggtcgtct gtatgccgca ggccgcgcgg gtgaacgttt cggcgtgcgt aactccggtg
    95281 ctatcaccgt ggtagaaggc attggcgaca acggctgtga atatatgacg ggtggtatcg
    95341 tctgtattct gggtaaaacc ggcgttaact tcggcgcggg catgactggc ggcttcgctt
    95401 acgttctcga tgaaagcggc gatttccgca aacgcgttaa cccggagctg gtcgaggtct
    95461 taagcgttga cgatctggcg atccatgaag agcatctgcg tggtcttatc accgagcatg
    95521 ttcagcatac cggttcccag cgtggtgaag agattctggc gaactggtca accttcgcca
    95581 ctaaatttgc gctggttaaa ccgaagtcca gtgatgtaaa agcactgctg ggtcaccgta
    95641 gtcgtagcgc agcagagttg cgcgtgcagg cgcagtaagg ggtagcaaca atgagtcaga
    95701 atgtttatca atttatcgac ctgcagcgcg ttgatccgcc aaagaaaccg ctgaagatcc
    95761 gcaaaattga gtttgttgaa atttacgagc cgttttccga aggccaggcc aaagcgcagg
    95821 ctgaccgctg cctgtcgtgc ggcaacccat actgcgagtg gaaatgcccg gtacacaact
    95881 acatcccaaa ctggctgaag ctcgccaatg aggggcgtat ttttgaagcg gcggaactgt
    95941 cgcaccagac aaacaccctg ccggaagttt gcggacgtgt ctgcccgcaa gaccgtctgt
    96001 gcgaaggttc ctgcaccctg aacgatgagt tcggtgcggt gaccatcggc aacattgagc
    96061 gttatatcaa tgataaagcg ttcgagatgg gctggcgtcc ggatatgtcc ggcgtgaaac
    96121 agaccggtaa aaaagtggcg attatcggcg caggtccggc gggtctggcg tgcgcggatg
    96181 tcctgacgcg caacggcgta aaagcgatcg tcttcgaccg tcacccagaa attggcggct
    96241 tgctgacctt cggtattccg gctttcaagc tggaaaaaga ggtaatgacg cgccgccgtg
    96301 aaatcttcac cggcatgggt attgaattca aactcaatac cgaagtgggc cgcgacgtgc
    96361 agctggacga tctgctgagt gattacgatg ccgtgttcct tggcgtcggg acttatcagt
    96421 caatgcgcgg cgggctggaa aacgaagacg ccgatggcgt gtacgcagcg ctgccgttcc
    96481 ttatcgccaa caccaaacag ttaatgggct ttggtgaaac ccgcgacgaa ccgttcgtca
    96541 gcatggaagg caaacgcgtg gtggtccttg gcggtggcga cactgcgatg gactgcgtgc
    96601 gcacgtctgt acgccagggg gcaaagcacg ttacctgtgc ctatcgtcgt gatgaagaga
    96661 acatgccggg ttcccgccgc gaagtgaaaa acgcgcggga agaaggtgtt gagttcaaat
    96721 tcaacgtcca gccgctgggt atagaagtga atggcaacgg caaagtcagc ggcgtaaaaa
    96781 tggtgcgcac agaaatgggc gaaccggatg ccaaaggccg tcgccgcgcg gagattgtgg
    96841 caggttccga acatatcgtt ccggcagatg cggtgatcat ggcgtttggt ttccgtccac
    96901 acaacatgga atggctggca aaacacagcg tcgagctgga ttcgcagggg cgcatcatcg
    96961 ccccggaagg cagcgacaac gctttccaga ccagcaaccc gaaaatcttt gctggcggcg
    97021 atatcgtccg tggttccgat ctggtcgtta ccgccatcgc cgaaggtcgc aaagcggcag
    97081 acggcattat gaactggctg gaagtttaag cgaggtaaca atgaattcgc cagacagtgt
    97141 ctggcgaatt tataaaacga gctatccaac taaattttaa gccattaaat cagccttaac
    97201 cttcactacc acctttttaa tctcaccagg ttcgccaaca acgcatcccg gtttatgcgg
    97261 ttctcctggc ataaacacgg cgaacattcc cggtttcagg atgatggctt gctcgttttc
    97321 aatggcgctg caaagctgat aatcatcttc atggtggaac tcttcacact gacgcgcagt
    97381 gcctgccatg ccaaacagaa tccgttcctc accgtttaat aacagctgga tatcaatgta
    97441 ttgttcgtgc aattcggctt ttttctcaac gggcgattga gtattaaatg tcatgacatt
    97501 cataaagata ttgtcgccct gtaattcgta acggccaggc gctttttctt gcggtctggc
    97561 agctaatgcc aacgttaacg cgtcctgtaa cgcaggatgt aatccggcag acggtaatga
    97621 ctgtacttca cccatcatca taatatttct ccctgggcca acagcgcagc cccaagtaaa
    97681 cctgcatcgt ggcggtagtg cgccgccagt aaatcaacat gaaatgccgc tggctcctgc
    97741 gccagatacg tttccaccag cgccagatac ccttctgcca gaccaacgct gccaccgacc
    97801 accacgcact ggcaatcagt tgtggcttta atatcagcga tcagccttgc aagcgtacgt
    97861 gcggagcggt gaatcagttg ctgcgcctgc tcatcgccct gcccggcgcg cgtgaaaata
    97921 gttttcgcat tcgcaccagc caactccccc tgcgctgcag ctgcaatgcc gcgaccagaa
    97981 gcaatcgctt ccacgcaacc tgtgcgtcca cagccgcaga ctggaccatg cggatcggca
    98041 agcgtatgcc cgatatgccc cgccagaccg ccagggccgg tacgcagttt accgccgctc
    98101 actacaccgc cgccaacgcc ggtggaaaca gtgataaaca ccatatcggt tatatcgcca
    98161 tccagcgcct gatactccgc ccatgctgcg gcctgcgcat cattaatggc aatggtcggc
    98221 aaattggtaa gttgctccag cgttttgact aacggaaagt gtaacaatcc accgagatta
    98281 tgcggattca gcgccagcaa gctgccgtcg cgaataattc cggttgaagc gatagcaacc
    98341 cgctgcgcat gtgcttgcaa cggagagact aatgcggata aggcatcacg cagcgcctgc
    98401 ggagtctggc tggcaggcgt aggaagttct cggcgatcgc ggatctgccc gtcagcgcca
    98461 atcagcgcgg cggcaagttt agtaccgccg atatcaatcg ccagtgtggt catagcaccg
    98521 cctttttcat cgctgtgttg taccactgac aaatgtgttc aagacgcgta atggcagaac
    98581 cgaccgtcac cgcccacgcg ccgtggcgca tcgcatccgc cgcctgagca ggcgtgttgt
    98641 aacgcccttc ggcaatcacc cggcatccgg cgtcactcaa cgttttcacc agcgccagat
    98701 ccggctcttc tggcgtttca ggcgtggtat agccagaaag cgtagtgcca ataatttcgg
    98761 ctcccagctt ttggcatgcc aggccgtctt ccggcgttga gcagtcggtc atcgccagta
    98821 aaccgtgatg gtgaatacgt gccagcagcg tttcaacagg caccggacgc ggtcggtcag
    98881 tgccgtcaat ggcgataatg tccgcgcccg cctgcgccag cgcatcaaca tcttcaatat
    98941 aggccgtgat gcgtaccgga gaatcctcca gatcgcgctt cacaatccca ataatcggca
    99001 cgctcaccac cgcacgcgtg gcttgcagat ttgccacacc ttcaatacga atggcaaccg
    99061 cgcccgcctg ctctgccgct aatgccatgg cagcgacgat ttcgggttta tcgagcgggc
    99121 tgtccggaac cggctggcag gagacaatca ggccaccgtt agcagcgatt ttttgatcca
    99181 gttgtgcaag taacgacata catcttccct tagcgaaagg cccggtacag agaccgggca
    99241 acaggattaa cttttggttt tgactaaatc gtttttggcg ctgccaaatg gcacggcacc
    99301 gctaaatggt ttgccgtcga tagcgtcatg agtacgcaat gcttccgggc gcaaccaacg
    99361 ctgaacacga gaaggcatat ccagaccaat cagcaggatc accacaaacg ttaaactaaa
    99421 cgagagcgag ccaagtgccg ttcccagatc cagacgttga gcgatcaacg cgccgaggat
    99481 tggagctagt gcaccgccca gtgcgccaac gttgtaggta aagcccagcc ccgccgcacg
    99541 ctggtcggta tcgaaataac cgccgatcag tttcggtaaa atccctgaga tgccctgacc
    99601 aagcatttgc tggaagaaca gtaacaaacc gagcacccag acgtttgcgc cgccaatcgc
    99661 aaataccgga ataatcagca gctgcgaggc cagcagacta caaacgtacg ctttgcgggt
    99721 tcccagccag tcaccgagga agccaccgac gcagcacccc accgccgcgc caaagccact
    99781 aaagaacagc acattggcga cagtatgcgg gtcataagcc agatcggttt tcagatacgt
    99841 tggcagcagc gcctgaatcg gccatgagta gaggaaagcg aacaacacga ccaccatcag
    99901 cattacgccc gttggccagc gtttgcccgt actctgcacc ataaagctga taaagattgc
    99961 ggcgcataac agcccgagta cagcgacgat tgcggcattt tgcaggttac cggcgaagca
   100021 gaaccacagc gcagtagccg ccgccagcgt cattacgata ttggcaatgc gatgttcacc
   100081 acggtaaaga atgtctacca tcgtgcgtac tggtgcttta cccccgtgtt tctctttcca
   100141 gtcttccgct tccgggatgt ttttacgcag ccagagagca aagatgattg gcaaaatgcc
   100201 gataaagaac agcgcacgcc agccccagac cggaaccacc agactataga cctgagcggc
   100261 aacgacggcc cccactgaga agcctgaaat cagaaaacca ctggctttgt tacgcagatg
   100321 ctttggccag ctttcaatga cataggtggc gctggaaccg tattcacccg ccatccccat
   100381 gccgatgacc agacgagcga taaacatggt gatgtagcct ggcgcaaagc cgcaggccag
   100441 cgtcccggcc gagaagagaa cgatgctggt gaccattgcc agacgacgcc cgtagcggtc
   100501 acccatagcg ccgagcatca ggccgccgaa ccagcgagag ataaaggctg cggagatcag
   100561 acttgccgcc tgcaccgtcg tcagcccgaa ttcaccctgt acttcggtga gtaccagggc
   100621 gattaaaacg aaatcaaaac cgtcaagcag atatcccaac caggcagcgg aaaatgcccg
   100681 ccattgtgcg cggttaagat ggcgatacca cgggatattc tgggttgtag tactcattgt
   100741 gagtctcccg cggtgggcga tgcccacacg ctttggtatg aaaattgtag ggtacagatg
   100801 cgtttatttc ccctcacccg gtaggggcga gcgaggggaa acaactcacc cgcgctcttg
   100861 catcaactgc tgagccagcg ccttcagttc tggcagatat ttttcatcta ccggaccaaa
   100921 cggtttgcgg cacagcggca cagaaacgac atccatataa tgcaggacag ttttcagccc
   100981 acggaatacg ccagttttga tcagtaaatc aatgactttg ttgcactcag tttgcagttt
   101041 ctgcgcggtc tggatatcgc cttctttcag cgccttcacg atcccctgat aacgccagcc
   101101 catgatgttg taagtgctgc cgataccgcc gtctgcgccc gccagaagac cagaggcgaa
   101161 gatttcgtcg taaccgttat agagcaccag atcaggatgt tcacgacgga tctgctccat
   101221 ctgatagaga tcgccagagg tctgtttcag cgcacctacg ccaggcagcg taaccaaggt
   101281 gttgatctga tccagggtca gttttacccc gctcagggct ggaatgttgt acaccaccat
   101341 cggcaaccca tccgctgaat caataattgc ccgatagtga tcgcagtgtt cttcaaagct
   101401 gaaaggatag tagaacggcg tgacggcgga gacggcatcg aagccataac gtttagccga
   101461 tgccgcaagt tgttggcttt cggcggtgct gacgcaaccg acatgggcga tgagtttaat
   101521 cttacctttc gcctcttcag cgacgatttc cagtacctgt tcgcgctcgg aaaggctttg
   101581 tacaaaggct tcgccggtcg aaccacccac gtacaaaccg tcgatgccct gctgaatatt
   101641 gaactgaacc aggcggcgca gactcgcttt atccagtgct tgttgttggt caaaaggagt
   101701 caggagtgca gccattacgc cacgtaaatt cgttgccata aatacctctg aagtgatgct
   101761 tgtctgataa acgatatacc tttatacctg ttataccaga tcaattaagc aacaccccat
   101821 acagaaagct tataatgcga tctgcttcac taaagtggca ttatttcttt ttgttggtgg
   101881 tctgaccgaa ggcgtgccag gtagcagaga cgctgttgag atgcgattgc aacgcgcgat
   101941 cggcttcgtc aggatcatga cggcggatcg cgtcaacgat cgcaatatgc tgttgatagc
   102001 taacgttgtt atgctcatgc agagcctgat cggtcacggt tggacgtgcg gcgattagcc
   102061 agtcgagcag ggcaacgtgg atcgccatga agattgggtt acccgggatc tccgccagaa
   102121 cgcggtggaa atcaacgtct gagcgaatga atgccgcgtt gttatccagc gactgactgt
   102181 tgatttccag tgcttttgcc agcaaatcga tttgctcatc ggtggcgtgt tcagccgcat
   102241 agcgcaccag gctggattca aagaacagac gtaattgttc gaaatgggca atcccaccag
   102301 gatgagaaag gaaatctttc gccatgccgg aaagctcgcc gatgatggtg tccgcagaag
   102361 gacgtgagac gcgggcacgt tcgccgttgt ttatttgcac cagacctttg cgttttaacg
   102421 ctgccagcgc ttcgcgcacc gaaggacgcc cgacgttaaa gaacgccatc agttcgcgtt
   102481 cagacggtaa ttgttcacct tcgccaaatt cacgacggcg gatcatctgt tccagctctt
   102541 cttccaccat ttcggagagt tttttacgcg ccagcgggcg gctgcgcaag ttgcgcccga
   102601 tagtggtagt agaatcttca gcttgcggat caaatgcgtt cataggactc attcaggaaa
   102661 atgcgttagc ggataataac gacgctatcg tagcacagta tcaaagtcag gcgaaaagat
   102721 gacagatagc aaaacaggcc acatgggcct gttttcattt tacttcacaa cgcgtaatgc
   102781 cggtcgacca ccgcgtggtg gctgcggagg ttcatcgtca ggatgagttt catcatcgtg
   102841 atctggcttg tcgccatcga taaccgacat aacggtttcg ttgtctgccg atgcctcttc
   102901 atcattcatg atgctggcat cttcatcgta ggcagcttca ggctcaaaca tcgtgcctgc
   102961 gccattttca cgggcgtaga tagccagcac ggcagccagc ggcacagaaa cctgacgcgg
   103021 aatgccacca aagcgcgcgt taaagcgcac ctcatcattc gccagttcca gattgccgac
   103081 agcacgcggc gcaatgttga gtacgatttg cccgtcacgc gcatattcca taggaacctg
   103141 cacgccaggg agcgtcacat ccaccaccag gtgcggcgtg agctggttat ccagcaacca
   103201 ctcatagaat gcacgcagca gatagggacg acgtggtgtt agctgtgaca aatccataca
   103261 gattaactcc ggcccagacg catttcacgt tctgcttcag ttaaagaagc aaggaaagag
   103321 tcacgttcaa agacgcgggt catatagcct ttcagctctt tcgcacccgg gccgctgaac
   103381 tcgatgccca gttgcggcag acgccacagc agaggagcaa ggtagcaatc gaccaggctg
   103441 aactcatcgc tcaggaagta cggcttctga ccgaagaccg gcgcaatcgc cagcagttct
   103501 tcgcgcagtt gcttacgtgc ggcatcggct tcagaagctg aaccgttgat gatggtgttc
   103561 atcagcgtgt accagtcttt ttcgatgcga tgcatgtaca gacggctttc accgcgagct
   103621 accgggtaaa caggcatcag tggcggatgc gggaaacgct catccagata ttccataatg
   103681 atgcgagatt cccacagggt cagctcacga tccaccaggg tcggaacgct ctgattcggg
   103741 ttgaggtcaa tcagatcctg aggcggattg tccttttcca cgtgttcgat ctcgaaactt
   103801 acacctttct cagccagcac aatgcggacc tgatggctat agatgtcagt aggaccggaa
   103861 aacagcgtca ttaccgaacg tttgttggca gcgacagcca tgaaaacctc caggtatagt
   103921 cagaattttt actgctacca gccaccaggt ggccagtcag aagttgtgtt acccagtaag
   103981 gaacgactct ctttgttcga aaatcaaaca aaaaatgagc aatacccgac atttgggcag
   104041 aaaattggat gatagtttac cagattttgc gacctttgtg gtgagtcgat gccggaaatg
   104101 gggaaaaaga gatgcgcttt agtctgaaat agttgactta gtcccttatt ggcgatgtgg
   104161 tttttgtttt acctgtctgt caggtggcag caaaaagcaa ctttccattt tttacgctga
   104221 tgcagatttt agccataaaa aaacccgccg aagcgggttt tttcgcaaat tgttttctgc
   104281 cggagcagaa gccaattaac gtttggagaa ctgcggacga cgacgtgctt tacgcagacc
   104341 gactttctta cgttcaacct gacgagcgtc acgagtaacg aagccagctt tacgcagttc
   104401 agaacgcagg gactcgtcgt attccatcag agcgcgggtg ataccgtgac ggatcgcacc
   104461 agcctgacca gagataccac cacctttaac ggtgatgtac aggtccagtt tctcaaccat
   104521 gtcgaccagt tccagcggct gacgaactac catgcgagca gtttcacgac cgaagtactg
   104581 ttccagagaa cgttggttga ttacgatttt accgttgccc ggtttgatga aaacgcgagc
   104641 tgcggaactt ttgcggcgac cagtgccgta gtattgattt tcagccattg cctataatcc
   104701 cgattagatg tcaagaactt gcggttgctg tgccgcgtgg ttgtgctcgt tacccgcgta
   104761 aactttcagt ttacggaaca tagcacgacc cagcgggcct tttggcaaca tgcctttaac
   104821 cgcgatttca atcacacgct caggacggcg agcaatcatc tcttcaaagg tcgcttgttt
   104881 gataccaccg atgtggccgg tgtggtgata gtacactttg tcagtacgct tgttgccggt
   104941 tacagcaact ttgtcagcgt tcagaacgat gatgtaatca ccggtatcta cgtgcggagt
   105001 gtattccgct ttgtgcttac cgcgcaggcg acgagccagt tcagtagcca gacggcccag
   105061 agttttaccg gtcgcgtcaa caacatacca gtcgcgtttt acggtttctg gtttagctgt
   105121 aaaagttttc attaaaagct tacccaataa atagttacac gttggtgaac acccaaacgt
   105181 cttcaattgt tgaggttcac acgacaaagt ccggcaaacc taccccttcg aatagcctat
   105241 gccagcacac aaaaagtttc gggaaaaaaa actttcttgt aacgtggggt cgcaggatta
   105301 tagagaagtc ggggtcaaag atcgacccct ttttgtgatt tgtggcaggt tttaccccgc
   105361 caaatgctcg cgcttcaaat actcttcgct ttgcatctct tgcagacgtg acaggcaacg
   105421 ctggaactca aacttcagcc gctcgccctg ataaatttca tacagcggca cttctgcact
   105481 caccactaat ttgacatggc gctcgtaaaa ctcatccacc agcgcaataa agcgccgcgc
   105541 ttcgctctcc atcaaccgcg tcataactgg tacatcaaac aacatgaccg tgtgaaagag
   105601 gcgtgagagc gcaatatagt catgctgact gcgggcgtcg acgcacagcg tagtaaaaga
   105661 aaccgccagc gtctggttct cgacgcccat tgtcgccaat ggccgatggt tgatttctaa
   105721 cgtcggtgaa ttttctcgtt tcgcccccgc cagcgccaac catagtttat ccatttgcgc
   105781 ccgggtttca tcgttgaggg gcgaaagcca cagatgcgcc tgagtgagtg tacgcaggcg
   105841 ataatcaaca ccagcgtcca cgttcattac atcacaatgc tgtttaatgg catcgattgc
   105901 aggcaaaaaa cgcgcacgtt gcaggccatt tcgataaagt tcgtccggcg gaatatttga
   105961 cgtcgctacc agggtaatac cgcgggcgaa cagggctttc atcagaccgc caagtagcat
   106021 ggcatcggta atatcagaaa caaaaaattc gtcaaaacag agcacgtcag tttctgcttt
   106081 aaagcgatcg gcaataattt ccagcggatc ggtctgcccc tgcaaagcag ttagctcttc
   106141 atgcacccgc agcataaaac ggtgaaagtg caggcgctgt ttccgctctc ccggcagact
   106201 ttgatagaaa aggtccatca gccaggtttt cccgcgtcct acaccgcccc acatatataa
   106261 gccacgcact ggcatatgct ttgtgtcttc gcgtttaccc cacagcttac cgacccgcgc
   106321 cattagccca ctcgtcctgg gggctggtgg cgtgctattg acgagttcct tataaataat
   106381 ttccaggcgg ctgacggcct ctttttgaac gtcgtcgggt tgatggctgc cttcattgag
   106441 cgccttcagg tattgcgatg ttggggtaac gctttgcatg atcttattgt tattccttga
   106501 ataatcggtg cgccgttgtt cacggttgac gaaaaaaagg ccgttctaca ctacgcgata
   106561 tgctgtcggg attccacttc tgtggaatta acggttatag tggcataatc agccgcaggc
   106621 atggagcctg aagccaacac cctacggaaa caaaagacaa cgggagatgt tcatgacctg
   106681 ggaatatgcg ctaattgggt tagtcgtcgg catcattatt ggtgctgtgg ccatgcgttt
   106741 tggtaatcgt aaactacgcc agcaacaggc gttgcagtac gaactggaaa agaataaagc
   106801 tgaactggac gagtatcgcg aagagctggt tagccacttt gcccgcagcg cggaattact
   106861 ggataccatg gcgcacgact atcgccagct gtatcagcac atggcgaaaa gctccagtag
   106921 cctgctgccg gaactgtctg cggaagcaaa cccgttccgt aatcgtctgg cagagtctga
   106981 agccagcaac gatcaggcac cggtgcagat gcctcgcgac tattctgaag gcgcatccgg
   107041 cctgctgcgt actggcgcga agcgcgacta atttattttt ggggcgcagc cattgcgccc
   107101 tcctcttctc tccctccccg actatcattt aatctggtgt ctcattgtta gccgtctgaa
   107161 aattcaataa catcaaactg ttttgaatct cttttcttat cattcaggta cgagagcagg
   107221 aataatgaaa aaacaaaccc agctgttgag tgcattagcg ttaagtgtcg ggttaactct
   107281 ctcggcgtca tttcaggccg tcgcgtcgat tccaggccag gttgccgatc aggcccccct
   107341 ccccagtctg gctccaatgc tggaaaaagt gcttccggca gtggtgagcg tacgggtgga
   107401 aggaacggcc agtcagggac agaaaatccc ggaagaattc aaaaagtttt ttggtgatga
   107461 tttaccggat caacctgcac aacccttcga aggtttaggc tccggtgtca tcatcaacgc
   107521 caataaaggc tatgtgctga ccaacaacca tgtgattaat caggcacaga aaatcagtat
   107581 tcagctcaat gatgggcgcg agtttgatgc aaaactgatt ggtagcgatg accagagcga
   107641 tatcgccctg ttgcaaattc aaaacccgag caaattaacg caaatcgcta ttgccgactc
   107701 cgataaattg cgcgtcggtg attttgccgt ggcggtcggt aacccatttg gccttgggca
   107761 aaccgctacc tccgggatta tatctgcgtt aggccgcagc ggtctgaatc tcgaaggtct
   107821 ggaaaacttt attcaaactg atgcctccat taaccgcggc aattccggtg gtgcgctgtt
   107881 aaaccttaac ggtgagttaa ttggcatcaa cactgcaatc cttgcgcctg gcggcggtag
   107941 cgtcgggatt ggatttgcca ttcccagtaa tatggcgcga acactggcgc agcagcttat
   108001 cgactttgga gaaatcaaac gcggcctgtt aggtatcaaa ggcaccgaga tgagtgccga
   108061 tatcgccaaa gccttcaacc ttgacgtgca gcgtggcgcg tttgtcagcg aagtgttgcc
   108121 aggttctggc tcggcgaaag cgggcgtcaa agcgggcgat attattacca gcctcaacgg
   108181 caaaccgctg aatagctttg ctgagttgcg ctctcgtatc gcgaccaccg agccgggcac
   108241 gaaagtgaag cttggcctgc tgcgtaacgg caaaccactg gaagtagaag tgacgctcga
   108301 taccagcacc tcttcgtcgg ccagcgctga aatgatcacg ccagcgctgg aaggtgcaac
   108361 gttgagcgat ggtcagctaa aagatggtgg caaaggtatt aagatcgatg aggttgtcaa
   108421 aggaagccca gctgctcagg ctggcttgca aaaagacgat gtgatcattg gcgtcaaccg
   108481 cgatcgggtg aactcgattg ctgaaatgcg taaagtgctg gcggcaaaac cggccataat
   108541 cgccttgcaa atcatacgcg gcaatgaaag cctctaccta ctaatgcgtt aatgtcgtaa
   108601 accgggcatc aggctgacgt gtgatgtccg gttaactcgt ggtatgctgc tgccgttccc
   108661 ttttttaacg atgcctccat catgtttgtg aagctcttac gttccgttgc gattggatta
   108721 attgtcggcg ctattctgct ggttgccatg ccttcgctgc gcagccttaa cccgctttcc
   108781 actccgcaat ttgacagtac cgatgaaacg cctgccagct ataatctggc ggttcgccgc
   108841 gccgcgccag cggtggttaa cgtttataac cgcggtttga acaccaactc tcacaaccag
   108901 cttgagatcc gcaccctggg atctggtgta atcatggatc aacgcgggta tatcatcacc
   108961 aataaacacg tgatcaacga cgccgatcag atcatcgtcg ccttacagga tggacgtgtt
   109021 tttgaagcgt tactggttgg ctctgactct ctaaccgatc tggcggtgct gaaaattaac
   109081 gccacaggcg gtttaccaac gattccgatc aatccacgcc gcgtaccgca cattggcgat
   109141 gtggttctgg cgatcggtaa cccgtacaac ctcgggcaga ccattaccca ggggattatc
   109201 agtgccacgg gtcgaatcgg tctgaacccg accgggcggc aaaacttcct gcaaaccgat
   109261 gcttccatta accacggtaa ctctggcggc gcgctggtga actcgctggg cgaactgatg
   109321 ggcattaaca cgctgtcgtt tgataagagt aacgatggcg aaacgccgga aggtatcggc
   109381 tttgcgattc ctttccagtt agcgaccaaa attatggata aactgatccg tgatggccgt
   109441 gtgatccgtg gctacattgg cattggtgga cgtgagatcg ccccattaca tgcgcagagt
   109501 ggcggcatgg atcaactgca agggatcgtg gttaacgaag tgtcgcctga tggcccagcg
   109561 gcaaatgcag gcatccaggt caacgatctg attatctctg tgaataacaa acccgctatt
   109621 tccgccctgg agacaatgga tcaggtcgcg gaaattcgcc ctggttcggt gatcccggtt
   109681 gtcgtgatgc gtgacgataa acagttaaca ttgcaggtca ccattcagga atatccggcg
   109741 accaactaag gtcagcgtaa aaaaacaaaa accggagtct gtgctccggt tttttattat
   109801 ccgctaatca attacttatt aacgaactct tcgcccaggg cgatatcttt cttcagcgta
   109861 tccagcatac cttccagcgc gttctgttca aatgcgctca gagtaccgat agatttacgc
   109921 tcttccacgc cgtttttacc cagcagcagc ggttgagaga agaaacgagc gtactgaccg
   109981 tcgccttcaa cgtaggcaca ttcgacaacg ccttgttcgc cctgcagtgc gcgaaccaga
   110041 gacagaccaa aacgtgcagc tgcctggccc atagacaggg ttgcagaccc gccaccggct
   110101 ttcgcttcaa ccacctcagt acccgcgttc tggatacgtt tggtcagatc agccacttcc
   110161 tgctcggtaa aactaacgcc aggaacctgt gacagcagcg gcagaatggt aacaccagag
   110221 tgaccaccaa taaccggcac ttcaacttcg cctggctgtt tgcctttcag ttccgcaaca
   110281 aaggtgttgg aacgaatgat atccagcgtg gtaacgccga acagtttgtt tttgtcataa
   110341 acaccggctt ttttcagcac ttcagcagca atcgcaactg tagtgttaac cgggttagtg
   110401 ataataccaa tgcacgcttt cgggcaggtt ttcgcaactt gctgtaccag gtttttcacg
   110461 ataccggcgt taacgttaaa caggtcggaa cgatccatac ccggtttacg cgctacgcct
   110521 gcagagataa gaacgacatc tgcaccttcc agcgccggag tcgcatcttc acctgaaaaa
   110581 cctttgattt tcacagcagt agggatatgg ctcagatcga cagccacacc gggagtcact
   110641 ggagcgatat catacagaga gagttctgaa cctgaaggca gttgggtttt taacagtagt
   110701 gcaagcgcct ggccaatacc gccagcagcg ccgaggactg cgactttcat cctaaactcc
   110761 ttattatatt gataaactaa gatatgttgc tccgctgccg cgaccttaat ccacaaaatt
   110821 gccgtttaca atgaccacat ctcaagaatg tgtagtcacg caagtttagc gtttatgcat
   110881 ttaattgccg taatcaggaa cctaacttac gtaattaaca gtcacttatg cattagcgca
   110941 acattccaac aggtggtgac aatataccct accgctcagc caaaacaata tcaatttgat
   111001 aacaattaat ttacttttaa gcagaatttg caggccgtga cgcaggcatg tttctcaata
   111061 acgaaatttg ataaaatccc gctctttcat aacattattt cagccttctt cagggctgac
   111121 tgtttgcata aaaattcatc tgtatgcaca ataatgttgt atcaaccacc atatcgggtg
   111181 acttatgcga agctcggcta agcaagaaga actagttaaa gcatttaaag cattacttaa
   111241 agaagagaaa tttagctccc agggcgaaat cgtcgccgcg ttgcaggagc aaggctttga
   111301 caatattaat cagtctaaag tctcgcggat gttgaccaag tttggtgcgg tacgtacacg
   111361 caatgccaaa atggaaatgg tttactgcct gccagctgaa ctgggtgtac caaccacctc
   111421 cagtccattg aagaatctgg tactggatat cgactacaac gatgcagttg tcgtgattca
   111481 taccagccct ggtgcggcgc agttaattgc tcgcctgctg gactcactgg gcaaagcaga
   111541 aggtattctg ggcaccatcg ctggcgatga caccatcttt actacccctg ctaacggttt
   111601 caccgtcaaa gagctgtacg aagcgatttt agagctgttc gaccaggagc tttaatctct
   111661 gccccgtcgc ttctggcggc ggggaaaatg ttgcttttgc ctatcaaccc actgctttcc
   111721 cctgcgattc atttaacgaa tagtgcgttt tactgcgaca tatcattcac acaatgaata
   111781 catatagtaa aaaagcacat tatgcaaaat
//
LOCUS       DAFGPF010000004        93263 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFGPF010000004 DAFGPF010000000
VERSION     DAFGPF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 93263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93263
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.004"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            11..178
                     /locus_tag="LSX49_000362"
     CDS             11..178
                     /locus_tag="LSX49_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HBL7166829.1"
                     /translation="MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISIS
                     KIIGGCGPTAQ"
     gene            complement(286..1371)
                     /locus_tag="LSX49_000363"
     CDS             complement(286..1371)
                     /locus_tag="LSX49_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL7166830.1"
                     /translation="MKTFPLQSLTLIEAQQKQFALVDTICRHFPGSEFLTCGDLGLTP
                     GLNQPRITQRVEQVLADAFHAQAAALVQGAGTGAIRAALAALLKSGQRLLVHDAPVYP
                     TTRVIIEQMGLTLITADFNDLSALKQVVDEQQPDAALVQHTRQQPQDRYVLADVLATL
                     RAAGVPALTDDNYAVMKVARIGCECGANVSTFSCFKLFGPEGVGAVVGDADVISRIRA
                     TLYSGGSQIQGAQALEVLRGLVLAPVMHAVQAGVSERLLALLNGGAVAEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKLGALPYPVGAESKYEIPPLFYRLSGTFRQANPQLE
                     HCAIRINPNRGGEETILRILRESIASI"
     gene            complement(1383..2687)
                     /locus_tag="LSX49_000364"
     CDS             complement(1383..2687)
                     /locus_tag="LSX49_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfT family protein"
                     /protein_id="HBL7166831.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGILILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLI
                     AAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGMSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            complement(2699..3052)
                     /locus_tag="LSX49_000365"
     CDS             complement(2699..3052)
                     /locus_tag="LSX49_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HBL7166832.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGCFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            complement(3063..3941)
                     /locus_tag="LSX49_000366"
     CDS             complement(3063..3941)
                     /locus_tag="LSX49_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HBL7166833.1"
                     /translation="MSFDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     ARGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVGCTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTDLKAGIIAEIGSSEGKITSLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDFLLTTFIPQLRQSGFSQ
                     ADVDVMLRENPSQFFQ"
     gene            complement(3938..5164)
                     /locus_tag="LSX49_000367"
     CDS             complement(3938..5164)
                     /locus_tag="LSX49_000367"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL7166834.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLETLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFRDVIDRVEQALVSAGWQVERRGDDLQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     ISFDDAIKMGRIVREQVQVGRVITFGGLLTDSQCILDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVSNPYGVSWQNLVDSQRIMD
                     ITLNEFNTYPTAFICTNIQETDLAGHAEDVARYAERLQVVDRNLARLVEAMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGLVATQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSFRFAGDTL"
     gene            complement(5165..6328)
                     /locus_tag="LSX49_000368"
     CDS             complement(5165..6328)
                     /locus_tag="LSX49_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HBL7166835.1"
                     /translation="MFVEALKRQNPALISAALSLWQQGKIAPDSWVIDVDQVLENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVSDAVEQGTDVITVFTLDKAREISAAAVKAGRVQSVLLKVYSDDDFLY
                     PGQESGFVQHSLHEVVAEIQNLPGLHLAGLTHFPCLLWDEAAGKVLPTPNLHTLVQAR
                     DQLAKSGIAIEQLNAPSATSCTSLPLLVEYGVTHTEPGHALTGTIPANQRGDQPERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQRITETYLNAVDDSSIDYTL
                     PLAGEHPVSSAVVLCFRTQIFITRSDVVLVSGIHHGEPEIVGRYDSLGNPLEA"
     gene            complement(6412..6774)
                     /locus_tag="LSX49_000369"
     CDS             complement(6412..6774)
                     /locus_tag="LSX49_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL7166836.1"
                     /translation="METRLNLLCDAGVIDKDICKGMMQVVNVLETECHLPVRSEQGTM
                     AMTHMASALMRSRRGEEIEPLDDELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            complement(6791..7696)
                     /locus_tag="LSX49_000370"
     CDS             complement(6791..7696)
                     /locus_tag="LSX49_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166837.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELATECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLTHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGLCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGDSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRVDDYPMQQLL
                     RAVVDKHALLAHQQRVVSGEQEPSY"
     gene            complement(7858..8862)
                     /gene="trpS"
                     /locus_tag="LSX49_000371"
     CDS             complement(7858..8862)
                     /gene="trpS"
                     /locus_tag="LSX49_000371"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBL7166838.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP
                     "
     gene            complement(8855..9613)
                     /gene="gph"
                     /locus_tag="LSX49_000372"
     CDS             complement(8855..9613)
                     /gene="gph"
                     /locus_tag="LSX49_000372"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HBL7166839.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADILMERALTWARQERATLRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            complement(9606..10283)
                     /gene="rpe"
                     /locus_tag="LSX49_000373"
     CDS             complement(9606..10283)
                     /gene="rpe"
                     /locus_tag="LSX49_000373"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL7166840.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(10301..11137)
                     /gene="dam"
                     /locus_tag="LSX49_000374"
     CDS             complement(10301..11137)
                     /gene="dam"
                     /locus_tag="LSX49_000374"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HBL7166841.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVD
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            complement(11244..12530)
                     /gene="damX"
                     /locus_tag="LSX49_000375"
     CDS             complement(11244..12530)
                     /gene="damX"
                     /locus_tag="LSX49_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HBL7166842.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKARNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTSSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVSLPPISSTPTQGQTPAATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRDTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGGKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            complement(12622..13710)
                     /gene="aroB"
                     /locus_tag="LSX49_000376"
     CDS             complement(12622..13710)
                     /gene="aroB"
                     /locus_tag="LSX49_000376"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBL7166843.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHSIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGRFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            complement(13767..14288)
                     /gene="aroK"
                     /locus_tag="LSX49_000377"
     CDS             complement(13767..14288)
                     /gene="aroK"
                     /locus_tag="LSX49_000377"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HBL7166844.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(14689..15927)
                     /gene="hofQ"
                     /locus_tag="LSX49_000378"
     CDS             complement(14689..15927)
                     /gene="hofQ"
                     /locus_tag="LSX49_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HBL7166845.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSVAWQNDNIA
                     RQEAEQTRAQANLPLENRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSTLEQWVSQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQQAGGVGQVTT
                     LGSDLSVATATTHIGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            complement(15839..16243)
                     /gene="hofP"
                     /locus_tag="LSX49_000379"
     CDS             complement(15839..16243)
                     /gene="hofP"
                     /locus_tag="LSX49_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HBL7166846.1"
                     /translation="MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDALTLGTGTNCEPPHWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDADGG"
     gene            complement(16233..16673)
                     /gene="hofO"
                     /locus_tag="LSX49_000380"
     CDS             complement(16233..16673)
                     /gene="hofO"
                     /locus_tag="LSX49_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HBL7166847.1"
                     /translation="MNMFFDWWFATSLRLRQLCWAVWLLVLVTLIFLSSTHQEERDAL
                     IRLRASHHQQWAALYRLVDATPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            complement(16657..17196)
                     /gene="hofN"
                     /locus_tag="LSX49_000381"
     CDS             complement(16657..17196)
                     /gene="hofN"
                     /locus_tag="LSX49_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofN"
                     /protein_id="HBL7166848.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTS
                     NAEARVNAVLLQAEQQLTRSLQITKPRLLERQQLREQRLQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
                     GRWQFEYQLTRKVSDEHVL"
     gene            complement(17196..17975)
                     /gene="hofM"
                     /locus_tag="LSX49_000382"
     CDS             complement(17196..17975)
                     /gene="hofM"
                     /locus_tag="LSX49_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HBL7166849.1"
                     /translation="MAFKNWQIGLHLQQQEAVAVAIVRSAKECLLHRWWRLPLENDII
                     KDGRIVDVQRLANTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQMAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQRFLPFLPSHQQCLAWRDNEQWLWATRYSWGRKLAVGMTSAKELAAALSVDPES
                     VALCGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKVY"
     gene            18095..20647
                     /gene="mrcA"
                     /locus_tag="LSX49_000383"
     CDS             18095..20647
                     /gene="mrcA"
                     /locus_tag="LSX49_000383"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HBL7166850.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVVLSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVDDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRHDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            complement(20813..21373)
                     /gene="nudE"
                     /locus_tag="LSX49_000384"
     CDS             complement(20813..21373)
                     /gene="nudE"
                     /locus_tag="LSX49_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HBL7166851.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVFEAANRELKEEVGF
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     APDFNEARNVSALFLVREWLKGQGRV"
     gene            21693..23828
                     /gene="igaA"
                     /locus_tag="LSX49_000385"
     CDS             21693..23828
                     /gene="igaA"
                     /locus_tag="LSX49_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HBL7166852.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTSEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQEIR
                     GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMLFF
                     CLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMKIQAYYESCLNPQLITPSESLIE"
     gene            23893..24561
                     /gene="yrfG"
                     /locus_tag="LSX49_000386"
     CDS             23893..24561
                     /gene="yrfG"
                     /locus_tag="LSX49_000386"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HBL7166853.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            24572..24973
                     /gene="hslR"
                     /locus_tag="LSX49_000387"
     CDS             24572..24973
                     /gene="hslR"
                     /locus_tag="LSX49_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HBL7166854.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAVLLYEETAESVEKREKMALAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            24998..25876
                     /gene="hslO"
                     /locus_tag="LSX49_000388"
     CDS             24998..25876
                     /gene="hslO"
                     /locus_tag="LSX49_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBL7166855.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(25999..27207)
                     /locus_tag="LSX49_000389"
     CDS             complement(25999..27207)
                     /locus_tag="LSX49_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL7166856.1"
                     /translation="MKRLQAFKFQLRPGGQQEREMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDLERAYKNFFQKRAAFPR
                     FKKRGQNDAFRYPQGVKLDQENSRIFLPKLGWMRYRNSRQVTGVVKNVTVSQSCGKWY
                     ISIQTESEVSTPVHPSASMVGLDAGVAKLATLSDGTVFEPVNSFQKNQKTLARLQRQL
                     SRKVKFSNNWQKQKRKIQRLHSCIANIRRDYLHKVTTTVSKNHAMIVIEDLKVSNMSK
                     SAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLEHKQLWSGGQVLAVPPAYTSQRC
                     ACCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQSGRPLKQ
                     EPTEMIQATA"
     gene            27215..27412
                     /locus_tag="LSX49_000390"
                     /pseudo
     CDS             27215..27412
                     /locus_tag="LSX49_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313209.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27510..29234)
                     /locus_tag="LSX49_000391"
     CDS             complement(27510..29234)
                     /locus_tag="LSX49_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HBL7166857.1"
                     /translation="MDNVELSPATRWGMIATGLLQGLVCYLLIAWLAGKNLSWIVYGV
                     PATVAFSSVLLFSVISFKQNRLWGWLALVFIATLGMSGLLKWQTDGMTPWRAEKALWD
                     FGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
                     LWSELFKLVGITFFKTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIA
                     TGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASL
                     PWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGALAVLVLLVWSLGY
                     FVSIVWRKGQNPLDLQGKVNLAVSLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKN
                     TPDQVTIYMLEQSGRYGRAALESLKSDAEYMKDPKRARDLLMALDGEQHLQEQVSEKV
                     LADNVLIAPGSGKPDATFWSALIQDRYNVMTCIEKDACVLVEQDLNSDGQAERILFAF
                     NDDRVIVYGFDSARKEWDALDMSLLPRKITKEKLLTAAKDGKLGTRPKAWRDLTVDGE
                     TLEINLSK"
     gene            29612..31234
                     /gene="pckA"
                     /locus_tag="LSX49_000392"
     CDS             29612..31234
                     /gene="pckA"
                     /locus_tag="LSX49_000392"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBL7166858.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            complement(31311..32663)
                     /gene="envZ"
                     /locus_tag="LSX49_000393"
     CDS             complement(31311..32663)
                     /gene="envZ"
                     /locus_tag="LSX49_000393"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HBL7166859.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
                     "
     gene            complement(32660..33379)
                     /gene="ompR"
                     /locus_tag="LSX49_000394"
     CDS             complement(32660..33379)
                     /gene="ompR"
                     /locus_tag="LSX49_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HBL7166860.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            33607..34083
                     /gene="greB"
                     /locus_tag="LSX49_000395"
     CDS             33607..34083
                     /gene="greB"
                     /locus_tag="LSX49_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312275.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HBL7166861.1"
                     /translation="MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHR
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP"
     gene            34180..36501
                     /locus_tag="LSX49_000396"
     CDS             34180..36501
                     /locus_tag="LSX49_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBL7166862.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLSYLRELEERRQAILKSISEQGKLTDDLANAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYIDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTV
                     PSHRALAMFRGRNEGILQLSLNADPQFEEPPKESYCEQIIMEHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREVQPAGNSAMMDALAAAMGKKR"
     gene            36939..37166
                     /gene="feoA"
                     /locus_tag="LSX49_000397"
     CDS             36939..37166
                     /gene="feoA"
                     /locus_tag="LSX49_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HBL7166863.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            37183..39504
                     /gene="feoB"
                     /locus_tag="LSX49_000398"
     CDS             37183..39504
                     /gene="feoB"
                     /locus_tag="LSX49_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HBL7166864.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQIASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            39515..39751
                     /gene="feoC"
                     /locus_tag="LSX49_000399"
     CDS             39515..39751
                     /gene="feoC"
                     /locus_tag="LSX49_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HBL7166865.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLKQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLHEWWALR"
     gene            40018..40380
                     /locus_tag="LSX49_000400"
                     /pseudo
     CDS             40018..40380
                     /locus_tag="LSX49_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(40409..41179)
                     /gene="bioH"
                     /locus_tag="LSX49_000401"
     CDS             complement(40409..41179)
                     /gene="bioH"
                     /locus_tag="LSX49_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HBL7166866.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGALSLADMAEVVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPDEFCHLLVALKQRV"
     gene            41217..41900
                     /gene="gntX"
                     /locus_tag="LSX49_000402"
     CDS             41217..41900
                     /gene="gntX"
                     /locus_tag="LSX49_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HBL7166867.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRAARTDKTLCPQCGLPA
                     THSHLPCGRCLQKPLPWQRLLTVADYAPPLSPLIHQLKFSRRSEIASALSRLLLLEVL
                     HARRTTGLQLPDRIISVPLWQRRHWRRGFNQSDLLCQPLSRWLHCQWDSEAVTRTRAT
                     ATQHFLNARLRKHNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAATV
                     QVWCLCRTL"
     gene            41959..42534
                     /gene="nfuA"
                     /locus_tag="LSX49_000403"
     CDS             41959..42534
                     /gene="nfuA"
                     /locus_tag="LSX49_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HBL7166868.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            42898..44214
                     /gene="gntT"
                     /locus_tag="LSX49_000404"
     CDS             42898..44214
                     /gene="gntT"
                     /locus_tag="LSX49_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HBL7166869.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(44324..46408)
                     /gene="malQ"
                     /locus_tag="LSX49_000405"
     CDS             complement(44324..46408)
                     /gene="malQ"
                     /locus_tag="LSX49_000405"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HBL7166870.1"
                     /translation="MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVIVYTSGKKMPMVVEGSGEYSWLLTTEEGKQYKGHVTGGKAFNLPT
                     KLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYLANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDE
                     QMTAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMADPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKD
                     LDRRRRAAAKKK"
     gene            complement(46418..48811)
                     /gene="malP"
                     /locus_tag="LSX49_000406"
     CDS             complement(46418..48811)
                     /gene="malP"
                     /locus_tag="LSX49_000406"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HBL7166871.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRGNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWVKQCNPALAALLDKSLKKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQSDRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            49434..52139
                     /gene="malT"
                     /locus_tag="LSX49_000407"
     CDS             49434..52139
                     /gene="malT"
                     /locus_tag="LSX49_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HBL7166872.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTSDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFESAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV"
     gene            complement(52182..52601)
                     /locus_tag="LSX49_000408"
                     /pseudo
     CDS             complement(52182..52601)
                     /locus_tag="LSX49_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="catalyzes the conversion of terminal3'-phosphate of
                     RNA to the 2',3'-cyclicphosphodiester; incomplete; partial
                     in the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
     gene            52531..52968
                     /locus_tag="LSX49_000409"
     CDS             52531..52968
                     /locus_tag="LSX49_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005019152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL7166873.1"
                     /translation="MFCSCKEKLPASVAISRSATWRGNFRELSASVTRMATFATSGRI
                     TLDTVEDEINRLRYNWQESRPSTLTALLGAEAENIDLFDRMQLEHVIAICRQAKSLSA
                     AGRELFDISRQGKASVNDADRLRKYLARFGLTWEAMQDQHSSS"
     gene            complement(52950..53708)
                     /locus_tag="LSX49_000410"
     CDS             complement(52950..53708)
                     /locus_tag="LSX49_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HBL7166874.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDTMPPASVMQVLKDHHIQLELC"
     gene            complement(53725..54555)
                     /gene="glpG"
                     /locus_tag="LSX49_000411"
     CDS             complement(53725..54555)
                     /gene="glpG"
                     /locus_tag="LSX49_000411"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HBL7166875.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQSGHTDSGLHYRRYPFFAALRERAGPVTWVMMI
                     ACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            complement(54600..54926)
                     /gene="glpE"
                     /locus_tag="LSX49_000412"
     CDS             complement(54600..54926)
                     /gene="glpE"
                     /locus_tag="LSX49_000412"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HBL7166876.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHATQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            55116..56621
                     /gene="glpD"
                     /locus_tag="LSX49_000413"
     CDS             55116..56621
                     /gene="glpD"
                     /locus_tag="LSX49_000413"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HBL7166877.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYTWQARGLVNATGPWVKQFFDDGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLKVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGAISDLGEDFGHEFYEAE
                     LKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLMEYTQQRLSLAS"
     gene            complement(56675..57280)
                     /locus_tag="LSX49_000414"
     CDS             complement(56675..57280)
                     /locus_tag="LSX49_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000589351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166878.1"
                     /translation="MNKIRLYIYPVIFGFVIVPLLVWPTVIALAVLIFTLTFLAEIIF
                     SFPLLVVRISLQELQLELLVEYALFFSVMGGIGWQFSRRTPPELKNRLHCWLVFSPVY
                     FWLILSNFILYISPEKSALLENIRNFFLTFVWLPLNFSPFWPQPWTDFVGPISAQLGF
                     ALGYYCQWRSKNRSHRKKWGDWVTCLSLAILALGPLFNYLQ"
     gene            complement(57283..58050)
                     /locus_tag="LSX49_000415"
     CDS             complement(57283..58050)
                     /locus_tag="LSX49_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166879.1"
                     /translation="MHPTPAMQALIEQIYHIFRRYPAPQQFVVCCEYCLSQQEQKALR
                     NTSLRAIPYSLINAWNSSPGPDPQNSDEVRYFLPCLLEFVAQGQFDNIHEVFSLRRIN
                     LASKENWREDEREILQQFACQYMTDWVSGDEAVELQYKLEMFFRADIALSPLLDAIIS
                     VPGFWSAASLACLLNTYRDGYIRDNQDDIDKAITTQTNTWASNNQSILKERARQAIEN
                     PLKQSEQGTQYQAWEDEWMIDECLCAMYDASSESSGH"
     gene            complement(58153..59661)
                     /locus_tag="LSX49_000416"
     CDS             complement(58153..59661)
                     /locus_tag="LSX49_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL7166880.1"
                     /translation="MMQSGKWILTSLVMTFFGIPILAQFLAAVVAMLGAGLAAILEVC
                     NLLFTPTIYLLLNVFMLTLGAIIIFFSGRVWAGDSAPEKREIAAWRQCFFLLPALLTL
                     VGWIIALHLADYQFRQMGSGWLANLMLSWQGVLLLSLISGDYWWIVIIPVGAHISFSL
                     GYGWPTRHPLTGTSGLRCRNLLLFLLLLLGFVAGYQAYLYKQLNPGVGVRENIDTWAW
                     RPDKLNNQLTPLRGKPQIQFTQNWPRLDGATAAYPIYASAFYALSVIPEDFHVWDYLD
                     NSRTQEAYNKIVNGDADIIFVAQPSDGQKKRAEKSGVTLLYTPFAREAFVFIVNADNP
                     VNSLTEQQVRDIFSGAITNWRAVGGDDQEIQTWQRPEDSGSQTVMLSQVMKNVRMISP
                     QETEVASVMEGMINVVAEYRNTKNAIGYTFRYYATQMNADKNIKLLAINGIAPTAENI
                     RNDKYPYIVDALMVTRENTTSETQKLVEWFLTPQGQSLVEDVGYVPMDKTLH"
     gene            complement(59786..62233)
                     /gene="glgP"
                     /locus_tag="LSX49_000417"
     CDS             complement(59786..62233)
                     /gene="glgP"
                     /locus_tag="LSX49_000417"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HBL7166881.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNDLQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADYIWHIDPVRL"
     gene            complement(62252..63685)
                     /gene="glgA"
                     /locus_tag="LSX49_000418"
     CDS             complement(62252..63685)
                     /gene="glgA"
                     /locus_tag="LSX49_000418"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBL7166882.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            complement(63685..64980)
                     /gene="glgC"
                     /locus_tag="LSX49_000419"
     CDS             complement(63685..64980)
                     /gene="glgC"
                     /locus_tag="LSX49_000419"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBL7166883.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPGKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            complement(64998..66971)
                     /gene="glgX"
                     /locus_tag="LSX49_000420"
     CDS             complement(64998..66971)
                     /gene="glgX"
                     /locus_tag="LSX49_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HBL7166884.1"
                     /translation="MTQLAIGKPTPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVIDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNDRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALME
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            complement(66968..69154)
                     /gene="glgB"
                     /locus_tag="LSX49_000421"
     CDS             complement(66968..69154)
                     /gene="glgB"
                     /locus_tag="LSX49_000421"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HBL7166885.1"
                     /translation="MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDAT
                     DVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETAS
                     LICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVIL
                     DWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALY
                     WIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQV
                     SGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLT
                     FGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKAMHELDFDPY
                     GFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTD
                     SMHYHGSNAGNGGAVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            complement(69427..70530)
                     /gene="asd"
                     /locus_tag="LSX49_000422"
     CDS             complement(69427..70530)
                     /gene="asd"
                     /locus_tag="LSX49_000422"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL7166886.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELANPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            70722..71315
                     /gene="yhgN"
                     /locus_tag="LSX49_000423"
     CDS             70722..71315
                     /gene="yhgN"
                     /locus_tag="LSX49_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HBL7166887.1"
                     /translation="MNEIISATVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            complement(71361..72656)
                     /locus_tag="LSX49_000424"
     CDS             complement(71361..72656)
                     /locus_tag="LSX49_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312307.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL7166888.1"
                     /translation="MDADSSDSTVTPGRLPDGLSSCPCFYLGKKLMNLSANAQATLLL
                     TSDFSRAAASEYKPLSNSEWGKFALWLKHQRISPAELLVPQPQEKLTGWSDPRISQER
                     ILGLLARGHSLALAVDKWQRAGLWILTRGDADYPVRLKNRLRTDAPPVLFGCGNKALL
                     QAEGMAIVGSRDAPTDDLRYTQQLAAKLAQQGICVISGGARGIDECAMASALEVGGTA
                     VGVLADSLLKTSTLVKWREGLIAGNLVLISPFYPEVRFTVGNAMARNKYIYCLAESAM
                     VVRAGMTGGTITGAMEALKHQWLPMQVKPNQDMQSANSRLVENGASWSAEQAENVTIR
                     LPDVPGLMYDRALRNAQPELFSLHEDDANYAVMPAHTPVDFYQLFVAELAILAKESIS
                     IERLASCTGLTIEQISVWLNRAEEEGRVIRLGEGHYQFR"
     gene            complement(72563..74659)
                     /locus_tag="LSX49_000425"
     CDS             complement(72563..74659)
                     /locus_tag="LSX49_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RecQ family ATP-dependent DNA helicase"
                     /protein_id="HBL7166889.1"
                     /translation="MEKHGAELLLQRMLSNTSATFREGQWEAIDAVVNQRRKLLVVQR
                     TGWGKSAVYFIASKIFRDRGAGPTIIISPLLALMRNQVAAAERLGITAETLNSTNREE
                     WQRISDKLLQGGVDCLLISPERLANQDFLETVLYPVADRIGLLVVDEAHCISDWGHDF
                     RPDYRRILDILRQLPANTPILGTTATANNRVVEDIRQQLGDIVIQRGTLARESLALDA
                     LVLGEQSSRLAWLATVIPQFSKSGIVYTLTTRDAELVAEWLRKNGISAFAYYSGVTCE
                     GAEDSNTAREYLEQALLANKIKVLVATTALGMGFDKPDLGFVIHYQMPGSIVGYYQQV
                     GRAGRAIDSAVGILLCGGEDRAIHQFFRESAFPAEAQIHEILNVLSENDGLTLRGIEQ
                     RTNLRYGQIEKALKLLVAENPSPVVYTEKLWRRTIVSFSPDHERINHLMNQRKSELAD
                     VESYITTKECKMQFLRRALDEPSAERCGKCSSCLQHPLLSPDIDSDLLHAANLFIKHA
                     DLPLNLNKQVASGAFTQYGFKGNLPAGLQGSTGRILSRWGDSGWGKQVAQEKKTGRFS
                     DELVEACAEMVRQRWNPHPEPTWVCCVPSLRHLDLVPDFARRLAAKLGLPFIDAIEKV
                     VDNPPQKMQQNRFHQCQNLDGAFVITPPLMPGPALLVDDIVDSAWTLTVLTALLRQAG
                     CPTVYPLALASTSVKN"
     gene            complement(74800..76140)
                     /gene="gntU"
                     /locus_tag="LSX49_000426"
     CDS             complement(74800..76140)
                     /gene="gntU"
                     /locus_tag="LSX49_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HBL7166890.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRVH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(76144..76671)
                     /gene="gntK"
                     /locus_tag="LSX49_000427"
     CDS             complement(76144..76671)
                     /gene="gntK"
                     /locus_tag="LSX49_000427"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBL7166891.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RCNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(76810..77805)
                     /gene="gntR"
                     /locus_tag="LSX49_000428"
     CDS             complement(76810..77805)
                     /gene="gntR"
                     /locus_tag="LSX49_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HBL7166892.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSKSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(77898..78593)
                     /gene="yhhW"
                     /locus_tag="LSX49_000429"
     CDS             complement(77898..78593)
                     /gene="yhhW"
                     /locus_tag="LSX49_000429"
                     /EC_number="1.13.11.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="HBL7166893.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALVKDEQSVHQIAAERRIWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEILLFDLPPV"
     gene            complement(78716..79753)
                     /locus_tag="LSX49_000430"
     CDS             complement(78716..79753)
                     /locus_tag="LSX49_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL7166894.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTI
                     AQAKELFALAKSKGLIVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITNGAPNYVKESEVLTNLEILERGFE
                     QASPSAVSLAR"
     gene            80087..80575
                     /gene="yhhY"
                     /locus_tag="LSX49_000431"
     CDS             80087..80575
                     /gene="yhhY"
                     /locus_tag="LSX49_000431"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL7166895.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYYNTLQVPHPSEQMWLER
                     LTARPGIKQLVACIDGIVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKFGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
     gene            complement(80636..82369)
                     /gene="ggt"
                     /locus_tag="LSX49_000432"
     CDS             complement(80636..82369)
                     /gene="ggt"
                     /locus_tag="LSX49_000432"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBL7166896.1"
                     /translation="MIKPTFLRRVAIAALLTGSCFSTVAAPPVSYGVEEDVFHPVRAK
                     QGMVASVDVTATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKN
                     GNTTAIDFREMAPAKATRDMFLDDQGNTDSKKSLTSHLASGTPGTVAGFSLALDKYGT
                     MPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDK
                     LVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLISKEDLAAYKAVERTPIS
                     GDYRGYQVYSMPPPSSGGIHIVQILNILENFDMQKYGFGSADAMQIMAEAEKYAYADR
                     SEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTTHYS
                     VVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPSVPNVYGLVGGDANA
                     VGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAEATNA
                     PRFHHQWLPDELRVEKGFSPDTIKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASD
                     PRSVDDLTAGY"
     gene            82489..82929
                     /locus_tag="LSX49_000433"
     CDS             82489..82929
                     /locus_tag="LSX49_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HBL7166897.1"
                     /translation="MKRLLLLTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQ
                     TQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGG
                     MLNSNRNPDSSLNQQHMLPERRNGDMLNQPSTPQPDIPLKTIGP"
     gene            complement(82916..83659)
                     /gene="ugpQ"
                     /locus_tag="LSX49_000434"
     CDS             complement(82916..83659)
                     /gene="ugpQ"
                     /locus_tag="LSX49_000434"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL7166898.1"
                     /translation="MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAE
                     RCRKHGMMANIEIKPTTDTGPLTGKMVALAARELWTGMTPPLLSSFEIDALEAAQQAA
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNYKLLDKARVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(83656..84726)
                     /gene="ugpC"
                     /locus_tag="LSX49_000435"
     CDS             complement(83656..84726)
                     /gene="ugpC"
                     /locus_tag="LSX49_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol 3-phosphate ABC transporter ATP
                     binding protein UgpC"
                     /protein_id="HBL7166899.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTTGDIWIDRKRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVREPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLAGRVNNEGTHFELDGGIALPLNGGYRQYVGRKM
                     TLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGHWGEQKLVVRLAHQERPTAGS
                     TLWLHLPENQLHLFDGETGQRV"
     gene            complement(84728..85573)
                     /gene="ugpE"
                     /locus_tag="LSX49_000436"
     CDS             complement(84728..85573)
                     /gene="ugpE"
                     /locus_tag="LSX49_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HBL7166900.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQEVYAA
                     PMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            complement(85570..86457)
                     /gene="ugpA"
                     /locus_tag="LSX49_000437"
     CDS             complement(85570..86457)
                     /gene="ugpA"
                     /locus_tag="LSX49_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HBL7166901.1"
                     /translation="MPSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVTLFHDSYYLDAFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            complement(86555..87871)
                     /gene="ugpB"
                     /locus_tag="LSX49_000438"
     CDS             complement(86555..87871)
                     /gene="ugpB"
                     /locus_tag="LSX49_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HBL7166902.1"
                     /translation="MKPLRYTASALALGLALMANAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEARIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADIATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            complement(88268..88981)
                     /gene="livF"
                     /locus_tag="LSX49_000439"
     CDS             complement(88268..88981)
                     /gene="livF"
                     /locus_tag="LSX49_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HBL7166903.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRVQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            complement(88983..89750)
                     /gene="livG"
                     /locus_tag="LSX49_000440"
     CDS             complement(88983..89750)
                     /gene="livG"
                     /locus_tag="LSX49_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HBL7166904.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGMPLANGTPEQIRNNPDVIRAYLGEA"
     gene            complement(89747..91024)
                     /gene="livM"
                     /locus_tag="LSX49_000441"
     CDS             complement(89747..91024)
                     /gene="livM"
                     /locus_tag="LSX49_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HBL7166905.1"
                     /translation="MKPMHIAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASEIR
                     WQWVFIGTAVVFFFQLVRPAFQKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTLFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAVLLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            complement(91021..91947)
                     /gene="livH"
                     /locus_tag="LSX49_000442"
     CDS             complement(91021..91947)
                     /gene="livH"
                     /locus_tag="LSX49_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HBL7166906.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMLGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            complement(91995..93104)
                     /gene="livK"
                     /locus_tag="LSX49_000443"
     CDS             complement(91995..93104)
                     /gene="livK"
                     /locus_tag="LSX49_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HBL7166907.1"
                     /translation="MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQYIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENID
                     FVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYD
                     QDPTNQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA
                     NTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
BASE COUNT        22575 a        25541 c        23303 g        21844 t
ORIGIN      
        1 gggaatgtaa atgaacaaat ttattaaagt tgcactggta ggcgcagtac tggctacgtt
       61 aactgcatgt actggtcata ttgaaaaccg tgataagaac tgctcttacg actacctgct
      121 gcacccggca atttctattt ctaaaatcat tggcggttgc ggtccgactg cacagtaagt
      181 ctctgacaga aatcggctaa cgccggttta attgcctgac gccctcggag ttatccgagg
      241 gcgtatttgt ttctgcattc ttttcgaaaa tatcgtttac aacgattaaa tgctggcaat
      301 actttcacgc aagatccgca atatcgtctc ttcaccgccg cgatttgggt taatgcgaat
      361 cgcgcaatgt tctaactgcg gattcgcctg gcgaaacgtt ccggaaagtc gataaaagag
      421 cggcgggatt tcatatttcg actctgcacc aaccgggtaa ggcaaggcac cgagtttctg
      481 cgcctcttcc agcactctgg cggcaatcgg ctgatgaaac tccacaatca ataccttcga
      541 ctgtgcattg gcaatgacgg cgcttttcac ttccgccacc gcgccgccgt taagcaaagc
      601 cagcaaccgt tcagataccc ccgcctgcac cgcgtgcatc actggcgcga gcaccagacc
      661 acgcaacacc tctaatgcct gcgccccctg aatctgactg ccgccggaat agagcgtggc
      721 gcgaatccgg ctaataacat cggcatcgcc taccaccgca ccaacgccct ctggcccaaa
      781 tagcttgaag caggaaaatg tcgacacatt cgccccgcat tcgcagccga ttcgcgctac
      841 cttcatcacc gcatagttgt catcggttaa cgctggaaca cctgccgcgc gcaacgttgc
      901 cagcacgtct gccagcacat agcggtcctg cggctgctgg cgcgtatgct gcaccagcgc
      961 ggcatcaggt tgttgctcgt caacaacctg cttcagtgcc gacagatcat tgaaatcagc
     1021 cgtaatgagc gttagcccca tctgctcaat aatgacgcgc gtcgttggat aaaccggcgc
     1081 gtcatgcacc agaagacgct gccccgattt gagcaaagct gccagcgccg cacggatcgc
     1141 gccagtaccc gcgccctgta ccagcgccgc ggcctgtgcg tgaaacgcgt cagccagcac
     1201 ctgttccaca cgctgggtaa tgcggggctg atttagcccc ggcgttaagc ccaaatcacc
     1261 gcaggtaaga aactcgctgc caggaaaatg acggcaaatc gtgtccacca gcgcaaactg
     1321 cttttgctgc gcctcaataa gcgtcaggct ttgcagagga aacgtcttca taggtgcctt
     1381 ccttaagccg gaacgaacag gccaagccag taaagaacat tcagcaggat gccggtgatc
     1441 attactgcca cgaccggtgc cgccattttc tgtaccggac ggcccaggga ttcgttgagg
     1501 aagtaaatgg caaccgcgat agagaatccg gtatagcccg ccattttgat tgctgcaaag
     1561 atcgaaccga ccagcaacgc cacttccatc agcatattca tggcgttacg gatgttatcc
     1621 gacgcattac gtaccgacgg gtagcgcccc aaccatttgc cgatagaacg aagcagcaag
     1681 acttccgccg aaataaccac tgcgcctaat accgctgcaa ccatcggatt cggcgagaga
     1741 tagcccaccg cataaacaaa ggtaaagccc gcaactgcat acacgccggt ggctaacgcc
     1801 gtggtggcaa tcaacggcac aaaacccagc ccgcgcataa attctgccag tgccgcctgg
     1861 ttgattagtg tttgcgattg ttccggcgtt acgcctgcgg agtacgcttt ctccagtgtg
     1921 aagatcgaca cttcactacc ggcgaaaatc ttcatgctgg caacggcagc aatcaatgca
     1981 cccacgatgg cgatatacgg taagtttttg ataatccgtg atgtacgctc ttcaaacacc
     2041 gacataccgc tggcatcgat atcattttca tcacgatgac gcaggtcatg agttattgcg
     2101 atccccagca gcatcaccat gccaataaag atttcgatgg attcagggtt aagatgtggg
     2161 aaatagcgta ctaccaccac acgagtcatc agtaccacca cggcggcgat cagactttgc
     2221 ttccagccaa actggtagaa aatcgccacc aacgggaaca gtgcaaaagc tgaaaccacc
     2281 ggcgagctta attcccccag gctacctaat acatccaccg gtagcgcggt cagcagctgg
     2341 tttactggca acagacaggt gaggatcaat attccccaga tagcaccaag accaaacgcc
     2401 atcaggctgt ttatcgccag tacgccgagg atatcggtag gaagaaagag taaccatgcg
     2461 ttgagcagcc cggttttcag ggtaaaagag atccccaccg aggccacaaa accaatgctc
     2521 agaccaaaag cgatgctccc cgcctcgcga cggttcatat agccttcaat cagttgtggc
     2581 aggatcgggc ggataccgtc atgaaaaacg gccgccgagc gatgcgccag aagcgatgtc
     2641 atacccgtca ggcacgccac cacgataatc tgaatataca gatccatagt cgtgcctttt
     2701 attttagatg gttaatcagc atcggaatcg cgtgttcaac gtgctcaacg gaaaggccaa
     2761 acgccacttt tccttcagcg atcattttgg cgatatgttc gtctttcgct ttaatgcccg
     2821 gcttggcaat ggtgcaactt ttgttatagc caatcaccgc gatagcaatc gacaaggctg
     2881 cgcccgcacc ggtattacac gcgccgatgt agtaatccag ttgtccggat ttcactttca
     2941 ttgccgcttc catgtcgttg tgaatgaaaa cttcaaaaca gccaggagcc gtcgcttcaa
     3001 tggttttttt aatctgctca cgctgtaagc ctgcaacgcc aatctttttc atgagtctgt
     3061 ccttattgga aaaattgaga gggattttca cgtaacatca catccacatc ggcctgactg
     3121 aatcctgact ggcgcaattg cggaataaag gtggtcaata aaaagtcata gccataacca
     3181 ccgttggctt ttaaatgaga gcgccgcgta atatccatcg acagcatgac gcggttcagc
     3241 aacccacggt cacgtagcgc atggagcatc gcaatgcgct tttcgtccgg gtagtaactg
     3301 ttcttgccga tggtgtcgaa ctgcacatac gcgccgagat cgatcatctt caaaatgttg
     3361 tcgagattgt ctttcagatc gcagtggccg acggtgacgc gcgaaagatc aactccgtgg
     3421 gcttgcaaca gagccagttg ctccagcccc atcgtgctga acgacgtatg cgtggagatc
     3481 gggcgtccgg tctggttatg cgccagcgcg gcggcaataa acaccttctc ttccagcgac
     3541 gtaatcttcc cttcgctgga gccgatctcc gcgataattc cggctttcag gtcagtgcca
     3601 tcgataccct gctcaatttc atcgaccatc tcctgcgcca gttcctgcac gctgcgggtc
     3661 gccacatgtt ccgggaaaaa cgcgtcctgg taataaccgg tacagcccac cacgttgatc
     3721 ccggtttcgc gcattacatc gagcataaat tgcgcattgc gccccatgta acggttggtc
     3781 atctcaatca cattacgcac gccccgggcc atcaggtcgt tcatctcctg gcaaatgaac
     3841 gcatactgat caaggcggca gtccacgttg tttttaaagc cggaaagatc aatatgcaga
     3901 tgctcatggg cgagggtgta gcccgtcgga tcaaaactca tagggtgtct cctgcaaacc
     3961 ggaaggagga aagaaaagag cgaccatttt gtggcggtgg cgcacggaaa aattcacaca
     4021 cggtagcccc cacatcagaa agcgtggtgc gcacaccgag ctgcgtagcg accagtcctt
     4081 gctgataaac cagcactggc accacttcgc gggtatggtg gctgtgaccg atggtcggat
     4141 cgttaccgtg atccgccatc acgaccaggc aatcatctgg ctgcatcgcc tcaacaagcc
     4201 gggcaaggtt acggtcaacg acctgcaaac gttcggcata acgtgcgacg tcttctgcat
     4261 gaccagcgag gtcggtttcc tggatattgg tacaaataaa cgccgtcgga taggtgttaa
     4321 attcgttgag ggtgatatcc ataatccgct ggctatccac caggttttgc cagctcacgc
     4381 cataaggatt gctgacgata tctgccacct tacccaccag cacggttggc acgcccgctt
     4441 catacagttt ttgcggcacc tgcacttttt catcgacacc gtagcccata tgtacgacct
     4501 ggaaaccgtt gtcataggcg ccagaacgcg gcgcattgat accaataaag cgcccttctt
     4561 tgctttctgc ggcatcgagg atgcactggc tgtcggttaa caggccacca aatgtaatga
     4621 cccgaccgac ctgtacctgc tcacgcacga tacgacccat tttgattgcg tcgtcaaaag
     4681 agatcacaga gagattggcg gtgatgttat agacctgacc taaatccgcc tcgagattat
     4741 cgccaatcgc aaccgcctga ttgacccaca gaaattgcag atcatcgcca cgacgctcaa
     4801 cctgccagcc agcggaaact aatgcctgct caacacggtc aatcacatca cgaaagggca
     4861 tccgcagcgg cggtaatggg cgcgtaccta aaatttcctg atgccccata aaggtatcgc
     4921 caccttcatg ttgcagctct gccacgcccc aggttgcgga gtctgacggc tgcatatcgc
     4981 caggcgcata acccaatgcg ttgattagcc ccagcgtctc cagcgttggt agctgcaaat
     5041 gcggcaactg gctcaggatg tgaccacagg tattcgcccc ggcatcctgc ggacgcacca
     5101 acgtgacatc tttcattgcc cctacgccaa agctatcaat cactaacacc acaaatcgcg
     5161 ccatttacgc ctccagaggg ttgccgaggc tgtcataacg accaactatt tctggttcgc
     5221 catggtgaat accggacacc aacaccacat cgctacgggt gataaaaatc tgcgtgcgaa
     5281 aacagagcac cactgcactg cttaccggat gctcgcctgc cagcggcagg gtgtagtcga
     5341 tactgctgtc atccacggcg ttgagatatg tttcagtaat tctttgattt tctggcgtaa
     5401 acaccagcgc atgttgcgcg tgaccacgac ggtagtaacc gccgccgtag cagtagctgt
     5461 cgccacggaa atgatgggag atttcactta accagagcat cgcgatacgt tcaggctgat
     5521 cgccccgctg gtttgccgga atagtgcccg tcagcgcatg accgggttcg gtatgagtca
     5581 caccgtattc caccagcaat ggcagcgacg tgcagctggt cgctgaaggc gcgttcagtt
     5641 gctcaatcgc aataccagat ttcgccagtt gatcccgtgc ttgtaccagc gtgtgaagat
     5701 tcggtgtcgg caaaactttc ccggcagcct catcccaaag caggcaaggg aaatgggtaa
     5761 gtcccgccaa atgtagcccc ggcagattct ggatttcagc aaccacctcg tgcagcgaat
     5821 gctgtacaaa accgctctcc tgccccggat aaagaaaatc atcgtcgcta taaactttga
     5881 gcagcacaga ctgcacacgt ccggccttca ccgctgccgc agaaatttcc cgcgctttgt
     5941 cgagggtaaa cacagtgatg acgtcggttc cctgttcaac ggcgtcagaa acctgatgac
     6001 aagggatttg taccagatgc ccctgatgcg ctaccggcaa accggcgcgg cgcatgactc
     6061 gcgcctcttt gtaatccacc gccacaatgc cgctgtagcc cagagccagc agtttttctg
     6121 ccagccacgg attacgaccg aattgtttgg tcatcagata cagttcaatg ccgtaaagcc
     6181 gcgccgtctc aatcagccgc ttgccgtttt ccagaacttg atccacgtcg atcacccaac
     6241 tgtccggggc gatcttgccc tgctgccaca aacttagtgc ggcggaaatc agcgccgggt
     6301 tctggcgttt caatgcttct acaaacatct tgttgcctcg tttctgttcc ttgaattaaa
     6361 tattcatttt tttgaatatt taggttgtac gacgtggatt tatcgggagc ttcaaacctc
     6421 ttcgttagca gccatccata atccataaag gttggccagc aaatagcctt cttcacacgg
     6481 gttaacttcc agtgcaaatt ccttcaacaa tacctgatgc aattgcacaa cggcttgcca
     6541 gtggctggat tgcgccagtt ccgccagcaa ttcgtcatcc agcggctcta tttcttcacc
     6601 acggcgactg cgcatcagtg cactcgccat atgtgtcatc gccatcgttc cttgctcact
     6661 gcgcaccggt agatggcact ctgtttccag tacattgacg acctgcatca tgcctttgca
     6721 gatgtcctta tcaataacgc ctgcatcgca aagcaggttg agtctggttt ccatatcaga
     6781 tgcctttcgt ttaataactg ggttcctgtt ccccactgac tactcgctgt tgatgagcaa
     6841 gcagggcatg tttatcaaca actgcacgca gcagttgttg cattgggtaa tcatcgactc
     6901 gcgtcaggac cacggcttcg gtggcctgta aaaatcgcgg atcgtctgtg agcggcgtcg
     6961 cttctaatcc cagcatggtc agttcgtttt ccgccactac gttccagata accgcgtcaa
     7021 catcgccttt aacaatgcgt tgtaaactct cgtgataaga gagatcgact cgttccacat
     7081 cactatcgcc aaaaaagaca tcggtcatga ttttctgatc cgccgaacgg ttatccagcc
     7141 ccacgcgctt cacgtttgcg gactcgcctt tacggcaaat caactggtgc tcgccaacgt
     7201 aggtatgcgg tcccaactcc agcgcgaggc ataatccttt ttgcgtgaga taactttccg
     7261 ccgccagtcg cgaaaccacc gccatgtcat acacgccgtt aagtaaacac tccacgcgaa
     7321 tatccgcgcc gcgcatatgc gcatagtaaa aaggaatgcc atcaaactgg gctttcaatc
     7381 cgctcgccag gccttcgtac aaacgggtat agggcaaggg catcgcacat accacgttgt
     7441 tgatatccac atgagtcagc aatgctttgt tatccatctc aaccagataa ctgccattgc
     7501 gcccacggcg ttcaatccgt atcgctccgc ttgattccag cgttttcaac gcggcctgcg
     7561 tcaggccaac cgatgaacgg cattcagttg ccagctcatc tatggttttc agtcgattac
     7621 cgcacttttc acccaacaaa taacgggcca gtgtcgtgat aacgacgcct tcttttttga
     7681 taaacgttcg acgcataata tattttcaat aaaatgaatg tttatatctt catgaatttg
     7741 aagataaggc gcaacagcga gatgtggaaa cggcgaggcg cttcacattt tttcggatta
     7801 ttgcaaatga ggataaaaaa accgggtttc cccggttttt ttggcattaa tgttaaatta
     7861 cggcttcgcc acaaaaccaa tcgcttcgta caccgctttt agcgtacggg aagcgtgtgc
     7921 gctggctttt tctgcgccgt ctttcatcac ctgttgcagg aaggcttcat cgttgcggaa
     7981 acggtggtaa cgttcctgca attcagtcag cataccggaa acggcatcag ccacttcacc
     8041 tttcagatga ccatacatct tgccttcgaa ctgtttttcc agttccggga tgctctggcc
     8101 cgttaccgca gaaaggatat ccagcaggtt ggaaacgccc gctttgttct gcacatcgta
     8161 gcgaactact ggcggctcgt cggagtcagt gaccgcgcgt ttgattttct tcactaccga
     8221 tttcggatct tccagcaggc cgataacgtt attgcggtta tcgtcagact tggacatttt
     8281 cttggtcggc tccagcagcg acattacgcg cgcgccagat ttcggaataa acggctctgg
     8341 caccttaaag atatcgccgt acagcgcgtt gaaacgctgg gcgatatcgc ggctcagttc
     8401 caggtgctgt ttctggtctt cacccaccgg taccagattt gtttgataca gcaggatgtc
     8461 cgctgccatc agcaccggat agtcaaacag accagcgttg atgttctcgg cataacgcgc
     8521 agatttatct ttaaactgcg tcatgcggct cagttcgccg aagtaggtat agcagttcaa
     8581 tgcccagcct aactgcgcat gttccggcac gtgggactga acaaaaatgg tgcttttctc
     8641 aggatcgata ccacaagcca gatacaacgc cagcgtatcc agcgtcgctt tacgcagctt
     8701 ctgtgcatcc tggcgcacgg tgatcgcatg ttggtcaacg atacagtaaa tgcaatggta
     8761 gtcatcctgc atgtttaccc actgacgcag cgcacccatg tagttaccaa tggtcaattc
     8821 acctgagggc tgtgcgccac taaaaacgat gggcttagtc atttttcgat tcctgatttt
     8881 cgctatgcgg aagccctaat gcgggcagaa ggtcatttat agactgataa attacatcag
     8941 gctggctgag atcgatagcc tcgccgtagt tatatccgta ggttaagcca actgatgggc
     9001 aacctgccgc ttttgctgcc tgaatatcat tgcgtgagtc gccaacaaac agcatctgtt
     9061 gtggagcaat gcccatccgt tcagccacca gtaacagcgg gtccggatgc ggttttttgt
     9121 tttgcacatc atcaccacca atcaccacgc tgaagtattt ggcgatatct aaggcttcga
     9181 gcagcggcgc gacgaacggc gtcggtttgt tggtgaccag gcctagcggc aggcctttag
     9241 cctgcaacgc gcccaacgta tcggcaacat gcgggaacaa aaacgtcccc tcttcggcaa
     9301 cctcgccata gtagcgatcg aacagtttac gcagaatacg tacctgttct tctgccggaa
     9361 tgtcgtcatc aacgggcggt ttacccattg ttttacgcag agtcgcacgt tcctgacgcg
     9421 cccaggtcaa tgcgcgctcc atcagaatat ctgcgccgtt accaatccag gtaataacgc
     9481 gttcttcacc tgcgacaggc aactccagcg catacagcgc catatctacc gcagcagcaa
     9541 gaccgggtgc actgtcaacc agcgtaccgt cgagatcaaa agcgacgccg cgaatatctt
     9601 caaacttatt catgacttac ctttgccagt tcactgcgca tttcatcaat gacttttttg
     9661 tagtctggct ggtcgaagat tgccgaacca gcaacaaaca tatccgcgcc cgccgcagcg
     9721 atttcgccaa tgttgttcac cttcacgcca ccgtccactt ccagtcgaat gtcaaagcca
     9781 gactcgtcga tacgacgacg tacttcgcgc agtttatcca gtgtttgagg aatgaaagac
     9841 tgaccgccga aaccagggtt aacagacatc agcaggatca catccagctt gtccattaca
     9901 taatccagat agctcaatgg tgtcgccggg ttaaatacca gacccgcttt acagccattt
     9961 tctttaatca gttgcagcgt gcggtcaaca tgctcggagg cttctggatg aaaggtaatg
    10021 atgctggcac cagcggcagc gaaatcaggc acaatgcgat cgacgggttt caccatcaga
    10081 tgtacgtcga taggggcggt aatgccgtag ttacgcaagg atttcagcac cattggccca
    10141 atcgtcagat tgggaacata gtggttatcc atgacgtcaa aatgcacgac atctgcaccc
    10201 gctgccaggg cttttgcggt atcttcaccc aggcgggcaa aatcagccga cagaattgag
    10261 ggggcaatca aatactgttt catccgcttc tccttgagaa ttattttttc gcgggtgaaa
    10321 cgactcctgg tttgtacaaa gccagcagtt cgtccacctt tttacgtgtg ccgccgttgc
    10381 tgcttatact gcgtcgaact ttgacgacat gcaattttgc gcgctgatac cactcacgcg
    10441 ttaacatcgt atcgtgattg gagatcagca ctggaatatg gcgatcaacc agaccttcag
    10501 cgatctccgc cagatgcgct tgttgttcaa gcgtaaaact gtttgtgtga tacgccgtaa
    10561 agttggcagt cgcagacagc ggcgcataag gcggatcgca atagacgaca gatgcatcat
    10621 ctgcgcgcgc catgctatcg gcgtaagact cacaatagaa aaaggcattc tgcgcttttt
    10681 cagcgaagtg atacaactct gcttccggga aatagggttt tttgtagcgg ccaaacggca
    10741 cgttaaactc accgcgcaga ttgtaacgac acaggccgtt gtaaccgtag cggttcaaat
    10801 ataaaaacag taccgcccga cggaacggat cctggctttt gttgaactct tcgcggaact
    10861 gatagtaaac ctcggcgcaa tttgtttcgg gaacaaatag ctcgcgtgcg gcctgtacgt
    10921 actcatcagt acgcatcttc acaatgttat agagactgat caggtcgcta ttgatatcgg
    10981 caaggatata acgagaaaag tcggtgttga gaaacaccga cccggcacct acaaaaggct
    11041 caaccagaca ttcgcccttg ggcaaatgcc gtttaatatc atcaagcagg ggatacttgc
    11101 cccctgccca cttcaaaaaa gcgcgatttt tcttcatgct gactaactaa ttacaccttc
    11161 tccggctgtg gagaaagctc cgacagcatc cagcgcttca ggcaactccc gcaatgataa
    11221 accattgcgg gagataacct tgattacttc agatcggcct gtacctgacg cagcggtttc
    11281 gcccacgggt ttttggcctg gacatctgct ggcaatgtag ataccgcttt tttcgcctct
    11341 tctttcgaag catacacgcc agaaaccagg acataccacg gctgaccatt acgcgtcgtt
    11401 tcatagacaa cgtagttttt cagattctct ttcttcgccc aaccgttcag gttgtcgtag
    11461 ttagaggaac tgctcagctg cagagtgtaa tggctggacg gtgccgattt caacgaacca
    11521 acattacctg cggtcttccc tccagcggct ggtgttgccg tggtttgcgc cggggatgcc
    11581 gtctgtactg gagccgtagt cgccgtctct tttggtgctg gcgtagaagt cgcagccggt
    11641 gcctttgtgc tcgccacagg ggcagctggt tcagttcgct tcggcgtctg tgcgactggc
    11701 ttcggttccg ttttcacggt tgcttgcggt tttttcggtt caatcaccgc ctgctgacga
    11761 gctgggcgcg tagtggccgg acgttcagcg gtttgcgttt tcgccgtgtc acgcgatgca
    11821 ttgccattgc gaacaggcgc aaccgttgcg ggttcggtcg gcaatgtaga attgaccgcc
    11881 acattgttca actgttgctg attttgtggc tgggtcagcg cattgttcag gtcaccctgc
    11941 acttcaacac gttgttgacc atccgttgcc gccggggttt gcccttgagt cggcgtagaa
    12001 gagatcggcg gcagagaaac atcctgctga gtattttccg cagacgtggt tcccggcgct
    12061 ggctgcacgc cattggcctg atcggtcgca ttgcctgcaa gatcaatact cttctcgcca
    12121 gacgcagttt gatcgctgga agaggtcgag ggggctttta gcgcagaacc gataccgatg
    12181 atcaacagca gtagaaccag aatgccgaca cccatcatca tatactgacg agaagcgggt
    12241 ttactggctg cttttttacg cttacgcgga cgacgctcta cgcgctcttc atccacggtt
    12301 tcatcttcgg attcgtcaat ttcttcttcg atttccggtt cctcattacg cgctttttgc
    12361 gcacgagtcg gacggcgatc gtcagtgtca tcaagttcaa tatcatcaaa attgatctgc
    12421 ggttcgccac gttcagtacg ctcagaacgt tcagaagatt gacgagaacg accagtacga
    12481 cgatcgctgg gatcgggttt cagctcgtct tctggtttga attcatccat ttaacacccc
    12541 actaaaaggt taatgcttac cacgttgcaa ttaacctgaa gctaatagac cgcttgataa
    12601 gcggcctgac ctttcttgtt gttacgctga ttgacaatcg gcaatggcgt taagaacaag
    12661 ctcgtgcgaa acgccgctgc gaacttcact cttaccaatt gccaacggaa gaattaagcg
    12721 catctctccc gcaaggactt tcttgtcacg cagcatatgc ggtaaatacg cctgcgcgga
    12781 catttcgcgc ggcccattga ccggtaaccc agcccgcgtg agcagggtta taatacgctg
    12841 cgtttcggca gaactaaacc gcccgagacg ttccgacgtc cgcgccgcca tcaccatacc
    12901 cgcagcgacc gcttcaccat gtaaccaatt gccatacccc atttcagctt caatggaatg
    12961 accaaaggtg tgtcccagat tcagtaaagc acgtaacccg gtttcgcgct cgtcggcggc
    13021 gacaacttct gctttcagct cacaacaacg gcgaatacag tacgccattg ccggaccgtc
    13081 cagacgcaac aacgcatcca gattctcttc cagccagtta aaaaacgcac cgtcaagaat
    13141 aatgccgtat ttgatgactt ctgccagccc cgacgctaac tcacgcgggg gaagcgtttt
    13201 cagacagtcg agatccacca ccactgaagc gggctggtag aacgcgccaa tcatgttttt
    13261 accgagggga tggttgaccg cagttttgcc gccaacggag gaatcgacct gcgacagtaa
    13321 cgtcgtcggg acttgaatga aacgtacacc gcgctgataa ctcgccgccg cgaagccggt
    13381 cagatcaccc actacgccgc cgccaagcgc caccagagta gtatcgcgac catgcggctt
    13441 ttgtaacaat gccgtaaaga cggtatcgag tacagccagg cttttatact gctcgccgtc
    13501 agggaggata acgctatcga cgttaacacc cgcctgttca agtacgccgc ggaccttatc
    13561 gagatacaga ggagccaggg tttcgttggt gaccaacatg acctgctcgc ccgatttcag
    13621 cggtaagaat gaagctggtt cattaaacaa accagatgcg atggtaattg ggtaactacg
    13681 ttccccgaga gtaacgacaa tcctctccat aacgcgacat ccaccttaat tactgtaccc
    13741 gcagacgagt gtatataaag ccagaattag ttgctttcca gcatgtgaat aatctggttt
    13801 gcaaccactt tagcgctttg atcatcagta cgaatggtca cgtcggcaat ctcttcatac
    13861 agcggattgc gttcattggc caacgcttcc agaacttcac gcggcggtgt ttcaacgtgc
    13921 agcaacgggc gttttttatc acgctgcgtg cgtgcaagtt gcttttcgat ggtcgtttca
    13981 agataaacga caacgccacg agcggaaaga cggttacgcg tttcacggga tttcacagag
    14041 ccgccgccag tagccagcac aataccctgt ttctcggtca actcattgat gaccttttct
    14101 tcgcgatcgc ggaagccttc ttcgccttct aaatcgaaaa cccagcccac atcagctccg
    14161 gttcgtttct caatctcttg atcggaatcg taaaattcca tattgagttg ttgagctaac
    14221 tggcgcccaa tagtgctttt tccggcaccc ataggcccaa ccagaaagat attgcgtttc
    14281 tctgccattt tttcggtact actaagacta ttcgttaatg ataaacccgc ttcgctcaga
    14341 gagcgccgca ggacatgaac tgaaacctca taagatattg cgagagtcag actgaaaatt
    14401 atctcaatac tccagcgggt ttggcaactg aataaatcac ccatccctct gcatatctgg
    14461 tcgctgcaag cgcgctgcct tgctaccacc gctctggcga taaatcaccg ggtaagatta
    14521 gcgtaaaaaa gacagcaaaa tgccgcctga atgataaatc atcatcatgg aacgcaggca
    14581 gcgaagagca ccaactctca aatcggtact ccttgtatgc taaatacctg cgcgcgtcaa
    14641 atagatgaaa cacgttcagc gtaaaaacat taccgctttt acggctgttt actcactgga
    14701 aaccagtcgt ggcgtgataa acaccactaa ctcgcgtcgt tcatcttctt ttccgtcatg
    14761 acgaaataat tgcccgaacc agggaatgtc gccaagcaac ggtacgctat cctgacccga
    14821 tttattttta cgggtaaaaa tgccgcccag cgccaacgtt tctccgcttt tgacctcgac
    14881 ctgcgtttcg atctcctgct tatcaatcgc cagcacttcg ccatctgcct gctgtagcac
    14941 ctgccccgga acgttctggc tgatgtgtaa tttcagccgg atgcgacctt tttgtaacac
    15001 cgtgggcgtg acttccatcc ccaggacggc ctctttaaat tccaccgacg tcgcgccact
    15061 ttccccgctg gaaacctgat atggaatttc gctcccctgt ttaatgctgg caggctgaag
    15121 atgtgaggcc agcagacgcg gactggcgat aatatccagc tgctgttttt gttcgagcgc
    15181 ggaaagctca agatccagta aacgtccgtt gatgcgtcca atgttaaaac cgatatgcgt
    15241 tgtcgccgtc gctacggaga ggtcgctgcc aagcgtggtg acttgcccaa cgccaccagc
    15301 ttgttgcgca tcggccagcg tccatttcac acctaactca cgcaaacttt tttcattaat
    15361 ggtgacaata tgcgccgaca gctcaacctg cccgaccggc agatccattt gcgataccca
    15421 ctgttcaagc gtgcttaacg ccgttttgtt atctcgcagc aaaaggcgat tggtgcgttt
    15481 atcgacggtc atactccctt tggcactcag tagcttctcc cccgctttcg ccagctctcc
    15541 ggcgtcggcg tattgcagag taatattgcg attttccagc ggcagatttg cctgcgcccg
    15601 cgtctgctcc gcctcctggc gggcgatatt gtcattctgc caggcaacgg aatgcaccga
    15661 gagaatgttg ccctcctggc gcgttatcaa tccggcgctt ttcactacag tttgtagtgc
    15721 ctgcttccag ggaacgtcag ttaaatgtaa cgacaccgta ccgctgacgt ctggcgaaac
    15781 caccaggttc aacttctcct gttcagccag cgcctgcaac acctgagcta ccggaacgtc
    15841 atccaccatc agcgtcactt tttgcggctt tgccgcctgt acgccgggta tcagcatcaa
    15901 cagtagtgcg gctatccatt gcttcatttg tatctccttg ccgttgccac aaccagtgtg
    15961 gcggttcgca gtttgtcccg gttcccagcg ttagtgcgtc tggcgtcagc tgtaagatcg
    16021 tccagccgtt ttccagcaca tcgttttgct gcacccgtcg ccattttttt tgcccatctt
    16081 ttattacacc gatgatgcgc tcgcctcgcc ctaccatccc ctgatagcgc cactggctaa
    16141 gttcgctaat ccggcataga tcttccggcg gtttaaaagg gtcacgcata ccggttaaaa
    16201 ggcacaatgc aatacctgcc aacaaccagc gtttaaccct catgcggcgt ctccagttgt
    16261 agcgtgaaca aaaggtcatc accttccacg cttaacgaaa aacggctcac gctgacgttg
    16321 cgctctgcca gccgtgtaaa tgccgacggc actgcttccc acagcgtttt caacgccaac
    16381 tcaccaccct gcgcggatgg atgccaggaa accagttgcg cgccggataa ctgaaaatcc
    16441 agtggcgaaa agggcagcgt tttttcttcg ctgaagggag tggcgtctac caggcgatac
    16501 agtgcagccc actgctggtg atgactcgcc cgtagtcgaa ttaatgcgtc gcgctcttcc
    16561 tggtgtgtcg atgacagaaa aatgagcgta actaacacca gcaaccagac tgcccagcaa
    16621 agctggcgga ggcggagtga tgtggcgaac caccagtcaa agaacatgtt catcgctaac
    16681 cttccttgtt aactgatact caaattgcca gcgtccctgc gcatcctgct gcgtggcccc
    16741 ccgctgattg agatgaaaag aagcatcctg gcggagtgac gtttccagcg cgtttaacgc
    16801 ggtaatgctt gttgtaagcc ccttgatctc cagcgttccc tgctgccagc ttatcgttgt
    16861 cagccaggca tgttcgggta aaagcgccgc tagtgcttcc agcgcagatt gccagtcgcg
    16921 ggtaaattgt cgctggcgct gacgttgcaa acgctgttcg cgtaactgct ggcgttccag
    16981 caaacgtggt ttcgttatct gtaagctgcg ggtgagttgt tgttccgcct gaagcaaaac
    17041 ggcgtttacg cgtgcttcgg cattgcttgt cagacgcagt attagcgtta tcccgacggc
    17101 cagcagcaaa ggcgcaacga acatcagcaa ccagaaacga agaaaagcgg tccggcgttg
    17161 ctgtcgccag ggcaaaaaat taattggcgg gttcatcagt acaccttccc aagcgccagc
    17221 cccagcgcga tggcaaagtc tccacctggt ggcggtagcg gcggctgacg aacagaaacc
    17281 gcctcccagg ggtcaaatcc gccttcgcca catagcgcga cgctttcggg atcaacagat
    17341 aacgctgccg ccagctcctt cgcgctagtc atccccaccg ccagtttgcg cccccagcta
    17401 tagcgcgtcg cccacagcca ctgttcgtta tcacgccagg ccagacattg ctgatgagaa
    17461 ggtaaaaaag gcaggaatcg ctgtaatgca ctggcatccg gagtgatcgc gctaacatga
    17521 acacgcaacc tttctgccag agtaagcagc gttgccagct ctttgctttg cgcggcagtc
    17581 acgttatagg cgggactgag tgagtcttcg ctgtaatcga agcgcaggga gtccggatcc
    17641 atatccagtt cacgggccat cgtcccggac agccaggcca tttgctcccg ctcaccgagg
    17701 gacatcgacg ggcgtggaaa tgaccgctgt aatgtgcgac tggcgggaaa cgccaacata
    17761 atgtgatgac gctgcggcag ttcgcgactc cacggtaaca acgtgttagc cagccgctgc
    17821 acatcaacaa tccgcccatc tttgataatg tcgttctcca gtggcaaccg ccaccagcgg
    17881 tgcaataagc attcttttgc gctccgcacg atagcaaccg ctaccgcttc ttgctgttgt
    17941 aaatgcaaac caatttgcca gttcttaaat gccattgtga tgatctcctt atcacccgtc
    18001 actctgacgg gtatatcaat gcgtctggct tgcctttata ctaccgcgcg tttgtttata
    18061 aactgcccaa atgaaactaa atgggaaatt tccagtgaag ttcgtaaagt attttttgat
    18121 ccttgcagtc tgttgcattc tgctgggagc aggctcgatt tatggcctat accgctacat
    18181 cgagccacaa ctgccggatg tggcgacatt aaaagatgtt cgcctgcaaa ttccgatgca
    18241 gatttacagc gccgatggcg agctgattgc tcaatacggt gagaaacgtc gtattccggt
    18301 tacgttggat caaatcccgc cggagatggt gaaagccttt atcgcgacgg aagacagccg
    18361 cttctacgag catcacggcg ttgacccggt ggggatcttc cgtgcggcaa gcgtggcgct
    18421 gttctccggt cacgcgtcac aaggggcgag taccattacc cagcagctgg cgagaaactt
    18481 cttcctcagt ccagaacgca cgctgatgcg caagattaag gaagtcttcc tcgcgattcg
    18541 cattgaacag ttgctaacga aagacgagat cctcgagctt tatctgaaca agatttacct
    18601 cggttaccgc gcctatggtg tcggtgctgc ggcacaagtc tatttcggta aaactgtcga
    18661 ccaactgacg ttgaacgaaa tggcggtgat agccgggctg ccgaaagcgc cttccacctt
    18721 caacccgctc tactcaatgg atcgtgccgt cgcgcggcgt aacgtcgtgc tgtcgcggat
    18781 gctggatgaa gggtatatca cccaacaaca gttcgatcag acacgcactg aggcgattaa
    18841 cgctaactat cacgcgccgg agattgcttt ctctgcgcca tacctgagcg aaatggtgcg
    18901 ccaggagatg tataaccgtt atggcgaaag tgcctatgaa gacggttatc gcatttacac
    18961 caccatcacc cgcaaagtgc agcaggccgc acagcaggcg gtacgtaata acgtgctgga
    19021 ctacgacatg cgccacggct atcgcggccc ggcaaatgtg ctgtggaaag tgggcgaatc
    19081 ggcgtgggat aacaacaaga ttaccgatac gctgaaggcg ctgccgacct atggtccgct
    19141 gctgcctgcc gcagtcacca gcgccaatcc tcaggaagca acggcgatgc tggcagacgg
    19201 gtcgaccgtc gtattgagta tggaaggtgt tcgctgggcg cgtccttacc gttcggatac
    19261 tcagcaggga ccgacgccgc gtaaagtgac cgatgttctg caaacgggtc agcaaatctg
    19321 ggttcgtcaa gttgacgatg catggtggct ggcgcaagtg ccggaagtga actcggcgct
    19381 ggtgtcgatc aatccgcaaa acggtgccgt tatggcgctg gtcggtggct ttgatttcaa
    19441 tcagagcaag tttaaccgag ccactcaggc actgcgtcag gtgggttcca acatcaaacc
    19501 gttcctctac accgcggcga tggataaagg tctgacgctg gcaagtatgt tgaacgatgt
    19561 gccaatttcc cgctgggatg caggtgccgg ttctgactgg cagccgaaga actcaccacc
    19621 gcaatatgcc ggtccaattc gcttacgtca ggggctgggt cagtcgaaaa acgtggtgat
    19681 ggtacgcgca atgcgggcga tgggcgtcga ctacgctgca gaatatctgc aacgcttcgg
    19741 cttcccggca caaaacattg tccacaccga atcgctggcg ctgggttcag cttccttcac
    19801 cccaatgcag gtggcgcgcg gctacgcggt catggcgaac ggcggcttcc tggtggaccc
    19861 gtggtttatc agcaaaattg aaaacgatca gggcggcgta attttcgaag cgaaaccgaa
    19921 agtagcctgc ccggaatgcg atattccggt gatttacggt gatacgcaga aatcgaacgt
    19981 gctggaaaat aacgatgttg aagatgtcgc tatctcccgc gagcagcaga atgtttctgt
    20041 accaatgccg cagctggagc aggcaaatca ggcgttagtg gcgaagaccg gcgcgcagga
    20101 gtacgcaccg cacgtcatca acactccgct ggcattcctg attaagagtg ccttgaacac
    20161 caatattttt ggtgaaccag gctggcaggg tactggctgg cgagcaggtc gtgatttaca
    20221 acggcatgat ataggcggaa aaacgggtac cactaacagt tcgaaagatg cgtggttctc
    20281 gggttacggt ccgggcgttg tgacctcggt ctggattggc tttgatgatc accgtcgtaa
    20341 tctcggtcat acaacggctt ccggagcgat taaagatcag atctcaggtt acgaaggcgg
    20401 tgccaagagt gcccagcctg catgggacgc ttatatgaaa gccgttcttg aaggtgtacc
    20461 ggaacagccg ctgacgccgc caccgggtat tgtgacggtg aatatcgatc gcagcaccgg
    20521 gcaattagct aatggtggca acagccgcga agagtatttc atcgaaggta cgcagccgac
    20581 acaacaggcg gtgcacgagg tgggaacgac cattatcgat aatggcgagg cacaggaatt
    20641 gttctgatta aaaaggcgct tcggcgcctt tttcagtttg ctgacaaagt gcacttgttt
    20701 atgccggatg cgggtgaacg cgttatccgg ccaacaaaaa attgaaaatt caataaattg
    20761 caggaacttc gtaagcctga taagcattat gcatcaggta aacttcacgc atttacactc
    20821 gcccctgccc tttcaaccat tcgcgcacga ggaacagcgc gctgacatta cgcgcttcgt
    20881 tgaagtcagg ggcttccagc aaatccatca tatgcgccag cggccagcgc acctgtggta
    20941 acggctctgg ctcatcgcct tccagtgatt ccgggtagag atcttgcgct accacgatat
    21001 tcattttgct ggaaaagtaa gacggtgcca tgctgagctt cttcaaaaaa gtcagatcgt
    21061 tcgcaccaaa tccaacctct tcttttagct cgcggttagc ggcttcaaag acgctttcac
    21121 ccggatcaat taatcctttc gaaaaaccta attcgtagga ttcagttccc actgcgtatt
    21181 cgcgaatcag gatcaggtga tcgtccacaa tcggcacaat catcactgct tcccggttgg
    21241 ttggacgcat tcgttcataa acacgccgca cgccattgct gaactccaga tccacgcttt
    21301 cgacggtaaa cagtcgggaa cgggctacag tttcaacatt cagaatggtg ggtttttgta
    21361 atgatttgct catcgtggga tctatgctgt gaaatcagcg gttattgtgc gatatcggac
    21421 acgctttcgg caatgtgaat tgcgcgttat ttacatttat gtaacttaat aaataatcgt
    21481 cctcaaatca aattaaaagt caataggttg aaataactcc aggaatttgc tgatattccg
    21541 ccttcagagg gtttgctatg atcagcggtt actgtgatgt gcttaatgat gctcaagtta
    21601 aactccacgc ttgccgatag ccaaccgcag aatcatgtat tgtgtccggt gcgactgacc
    21661 acgcctgaca gactaagtaa gatggggaaa gcatgagcac cattgtgatt tttttagctg
    21721 ctttgctggc ctgctcacta cttgcgggat ggctgataaa agtgcgatcc agacggcgtc
    21781 agctgccctg gaccaacgcc ttcgcggatg cgcaaacgcg taaactcaca tctgaagaac
    21841 gtagcgccgt tgaaaattat cttgagagcc tgacgcaggt attacaggtg cctggcccaa
    21901 cgggagccag cgcggcaccg atctctctgg cgctgaatgc cgaaagcaac aacgtcatga
    21961 tgctgacaca cgctatcacg cgttatggca tctctaccga cgatccgaat aaatggcgtt
    22021 actacctcga ttcggtagaa gtccacctgc cccctttctg ggaacagtac atcaacgatg
    22081 agaataccgt tgaactgatt cataccgatt cgctgccgct ggttatttca ctcaacggtc
    22141 atacgctgca ggagtacatg caggaaattc gcggctatgc cttgcaacct gttccgtcaa
    22201 cgcaggcgtc gattcgcggg gaagagagcg agcaaataga gctgctcaat attcgcaaag
    22261 aaacgcatga agaatatgcg ctgagtcgtc cgcgcgggct gcgcgaagcg ttgctgattg
    22321 tcgcctcctt cctgatgctc tttttctgcc tgattacccc ggatgtcttt gttccgtggc
    22381 tggcaggcgg cgcgttactg ctgctgggcg caggtctgtg ggggctattc gcgcccccgg
    22441 caaaatcctc cctgcgggaa attcattgtc tgcgcggtac accccgtcgt tggggattgt
    22501 ttggcgaaaa cgatcaggaa cagatcaaca atatttcact cggtattatc gacctggtct
    22561 atcccgcaca ctggcagccc tacattgctc aggatctcgg ccaacaaacc gatatcgata
    22621 tctatctcga ccgccacgta gtgcgtcagg ggcgatatct ttcgctccat gatgaagtaa
    22681 aaaactttcc gttacagcac tggctgcgca gtacgattat cgctgcgggc tcgctactgg
    22741 tgctgtttat gctgttattc tggatcccgc tggatatgcc gctgaaattc accctctcgt
    22801 ggatgaaagg cgcgcagacc attgaagcca ccagcgtgaa acaactggct gacgctggcg
    22861 tgcgggttgg cgatacattg cgtattagcg gtacgggaat gtgtaatatt cgcacttccg
    22921 gtacctggag cgcgaaaacc aactcacctt ttttaccgtt tgactgctcg cagatcatct
    22981 ggaacgacgc ccgctcattg ccattaccag aatctgaatt ggtcaacaaa gcgacggcat
    23041 tgaccgaagc agttaatcgc cagctgcacc ctaaaccgga agatgaatct cgcgtcagcg
    23101 cctcattacg ttcagcaatt caaaaatccg gcatggtatt gcttgatgat tttggcgaca
    23161 tagtactgaa gacagcggat ctgtgttctg ccaaagatga ctgtgtgcga ctgaaaaatg
    23221 cgctggtcaa tctcggcaac agtaaagact gggacgcgct ggtaaaacgc gccaacgccg
    23281 ggaaactcga tggcgtgaat gtgttattac gcccggtgag tgcggaatcg ctggataacc
    23341 tggtggccac ctctaccgcg ccgtttatca cgcatgaaac ggcgcgagcg gcacaatcac
    23401 taaacagtcc ggcccccggc gggttcctga ttgtcagcga cgaaggcagc gattttgttg
    23461 atcagccctg gccttcggca tcactttacg actatccgcc gcaagaacag tggaacgctt
    23521 tccagaaact ggcacaaatg ctgatgcata cgccgtttaa cgccgaaggt atcgtcacaa
    23581 aaatcttcac tgacgccaat ggtacgcagc atattggcct tcatccgatc ccggatcgtt
    23641 ccggtctgtg gcgctatctc agcaccacgc tgctgctact gacgatgctg ggtagcgcca
    23701 tttataatgg cgtacaggcc tggcgtcgtt accagcgtca tcgtactcgc atgatgaaga
    23761 ttcaggccta ttatgaaagc tgcctgaacc cgcaactgat caccccttcc gaaagcctta
    23821 tcgaataaca cgtttgcgcg gcaggttatg ctaccctgtc gcgcaaattg cttcactctg
    23881 gagatttccc tcatgcatat caacattgcc tggcaggacg tagataccgt tctgctggat
    23941 atggacggca cgttgctcga cctcgccttc gataactatt tctggcaaaa gctggtgcct
    24001 gaaacatggg gcgcgaaaaa cggagttacg ccacaggaag cgatggaata tatgcgccag
    24061 caatatcacg acgtacagca tacgctaaac tggtactgtc ttgattactg gagtgagcaa
    24121 ctgggtctgg atatctgtgc gatgaccacc gagatgggac cgcgtgccgt actgcgtgaa
    24181 gataccattc cgtttcttga ggcactgaaa gccagcggta aacagcgaat tttgctcacc
    24241 aatgcgcatc cgcacaacct ggcggtaaaa cttgagcata ccggtctgga cgcacacctt
    24301 gatttattac tttccaccca cacatttggt tatccgaaag aggatcagcg gttatggcat
    24361 gcggtggccg aagctacggg tcttaaagct gaaagaacgc tgtttattga tgacagcgaa
    24421 gcgattctcg atgctgccgc gcaatttggt attcgttact gcctcggtgt gactaatcct
    24481 gactccggga ttgccgagaa acagtatcag cgccatccgt cactgaatga ctaccgccgc
    24541 ctgatcccct cgctaatgtg aaggagacgc catgaaagaa aaacctgctg ttgaggttcg
    24601 actggataaa tggctatggg ccgcccgttt ttataaaacc cgcgcgctgg cccgcgaaat
    24661 gatcgaaggt ggtaaggtgc attacaacgg gcagcgcagc aagccgagca aaatcgtcga
    24721 gctgaatgcc acgctcactc tgcgccaggg aaatgacgaa cgcacggtga ttgtaaaggc
    24781 gattactgaa cagcgtcgcc ccgccagcga ggcagtcttg ctgtatgaag agactgcgga
    24841 aagtgtagag aaacgcgaaa aaatggcgct ggcacgtaaa cttaatgcct taaccatgcc
    24901 gcatccggac cgacgcccgg acaaaaaaga gcgccgcgac ctgttacgat ttaaacacgg
    24961 cgacagtgaa taactgtcac ctgcaagaga gatgattatg ccgcaacatg accaattaca
    25021 tcgctatctg tttgaaaact ttgccgttcg cggcgaactg gtaaccgttt cggaaaccct
    25081 gcaacagatc cttgagaatc acgattatcc gcagcccgtt aaaaacgtgc tggcagaact
    25141 gctggttgcg accagcctgt taaccgctac gttgaagttt gatggtgata tcaccgtaca
    25201 gctgcaaggc gacggtccga tgaatctggc ggttattaac ggtaacaaca accagcagat
    25261 gcgcggtgtg gcgcgcgtgc agggcgaaat tccagaaaat gccgacctga aaacgctggt
    25321 cggcaatggt tacgtggtga tcaccatcac cccgagcgaa ggcgaacgct atcagggcgt
    25381 ggttggtctg gaaggtgata ccctggcggc ctgcctggaa gattacttta tgcgttctga
    25441 acagctgccg acgcgcctgt ttattcgcac cggcgacgta gacggcaaac cggctgcagg
    25501 cggtatgttg ttgcaggtaa tgcctgcgca aaatgcccag caggacgact ttgaccacct
    25561 ggcgacgcta accgaaacca tcaaaaccga agaactgctg actttaccgg caaacgaagt
    25621 gttgtggcgt ttgtatcacg aagaagaggt gacggtttac gatccgcagg atgtggagtt
    25681 caaatgcacc tgctcgcgtg aacgttgcgc cgatgcgctg aaaacgctgc ctgatgaaga
    25741 agtcgatagc atcctggcgg aagatggcga aattgacatg cattgtgatt actgcggtaa
    25801 ccactatctg ttcaatgcga tggatattgc cgagatccgc aacaacgcgt ctccggcaga
    25861 tccgcaagtt cattaatgag tatgtccggc agagaggact ctgccggatt ttacgacgta
    25921 atggcctgat gcgctgcgct taccaggcct atgaattgac atcctccacg ccctgaagga
    25981 cgtggatccc tgctacgttc aggctgtcgc ctgaatcatt tcggtgggtt cctgcttcaa
    26041 cgggcggcct gactgcacca tctctccaca ggcaagaacg gcgtgccccg ccgctaaaat
    26101 gttacgagcg ccatttacat cggcgttcgc tgtatatcca catacctggc atctgaattt
    26161 actttgtgac aggcggtttt ctttcgctgt atgaccacag cacgcgcaac gctggcttgt
    26221 gtacgctggc ggaacagcaa gcacctgacc gccactccag agctgcttgt gctcaagctg
    26281 gcggcgcatt tcataccagc cctgatccag tatcgaacgg tttaaacctg attttgcccg
    26341 gacattgcgc cccggctggc tgaccgtacc cgctgctgac tttgacatgt tgctgacctt
    26401 caaatcctca atgactatca ttgcgtggtt tttgctgacg gtcgttgtga ctttgtgaag
    26461 gtagtccctg cggatatttg cgatacagga atgcagccgc tgtattttgc gtttctgctt
    26521 ctgccagttg ttgctgaatt tgaccttgcg gcttaactgt cgctgaagtc tcgccagcgt
    26581 cttctggttt ttctgaaaac tgtttacagg ctcaaagact gtgccatctg acagcgtggc
    26641 gagtttagcc acgccagcat ccagcccgac cattgatgct gaagggtgaa ccggagttga
    26701 tacttcactt tctgtctgaa tactgatgta ccacttaccg caggactggc tgacagtgac
    26761 atttttcaca actcccgtga cctgacggct attccggtag cgcatccaac caagtttcgg
    26821 cagaaaaata cggctgtttt cctgatcgag cttaacgccc tgcgggtagc ggaatgcatc
    26881 attctgtccc cgctttttga atcggggaaa agcagcccgc ttctggaaga agtttttgta
    26941 agcccgctca aggtctttca gtgactgttg caatggctgt gagggagaat ctttaagcca
    27001 ttgcgtttca gtggcatttt tccactcaac cagccaggaa gccattttcc cgtaagggat
    27061 gtatttatta ccggcctcat gattctcatt ctgaagcgcc agagcacgat tgaaaacgaa
    27121 acgacatgcg cctgcgaagc gcctcatttc acgctcctgt tgaccaccgg gtcttaactg
    27181 gaatttaaat gcctgtagtc gtttcacagg tcaaattata ttttggtcta tgaaaaaaga
    27241 aaccgatatc cggcgtggaa ggcattgtgt tttcctgatg catgttcacc tggtctttgt
    27301 cgccaaatac caacgccaga tttttgacca tgacgcgaca gaaaaactac gcacttactt
    27361 ttcaaatgta tgtgctgatt ttgaagctga acgggttgaa atggatggcg aacttatatc
    27421 cccgccctga aggacggggt tttaccgcgc accggataaa tcgcaagtta ttttggtcag
    27481 atacagcgtc gtatccgtta aaagcgttgt cacttactta agtttatttc cagcgtttca
    27541 ccatctaccg tcagatcgcg ccacgctttc ggcctcgtcc ccagttttcc atccttcgca
    27601 gctgtgagta atttttcttt cgttattttg cgcggaagta aactcatatc aagcgcgtcc
    27661 cattcttttc tggctgagtc aaagccatag acaatgactc tgtcatcatt aaaagcaaac
    27721 aggatccgct ccgcctgacc atcactattc agatcttgct cgaccagtac gcaggcgtct
    27781 ttttcaatac aggtcatcac gttatagcga tcctggatta aggccgacca gaatgtcgca
    27841 tccggtttac cagaacctgg ggcaattaac acattatcgg ctaatacttt ttccgatacc
    27901 tgttcctgaa gatgttgctc tccatctaac gccatcagca gatcccgcgc gcgtttcggg
    27961 tctttcatat actcggcatc gcttttcagc gactcaagcg ccgcacgtcc atagcgaccg
    28021 ctctgttcga gcatgtagat agttacctgg tctggcgtgt ttttaccgct ctgataacgc
    28081 gccatatgac tgttcacgct aatgcgcata ctgtccagca ccggcgaatt aagaagcacc
    28141 agtattacca acaccaataa cgaaaccgca aggttcactt tgccctgaag atcaagggga
    28201 ttttgccctt tacgccagac gatactgaca aaatacccca gcgaccatac cagtaacacc
    28261 agcaccgcca gcgcgccctg caagcggtcg acagtccagc cgtactgagc gacccgcagc
    28321 cataacgccc aggcggcgac gaacacatac agcggagcaa ccagcaaagc ggttttaatc
    28381 aggcaacgca atggccccgt ccagggaagt gacgcttttt gcggatcgcg gacaatagcc
    28441 attaagatca attgcaaaaa ggccagcgtc aacagcaacc cggcggcgga gatgtggcga
    28501 gaaatcgcgc tcaggcccgt aaacggcagg gtgataataa acatcagggt tagcaatgat
    28561 actaacggca gcaaccccgt ggcgattaac gtgaacaact tttgaataga gtcgattaaa
    28621 cgtgactgtg ttcgcgcgag gatcaccgcc agcgcggtaa ccagacctaa cgtgagataa
    28681 ataaaccagt cggttgcaaa aaagagcgtt ttgaaaaacg tgatgccaac aagtttaaac
    28741 aactcactcc acagtaaaag taccagccac gttaggccat tggcgagaaa aatcaccagt
    28801 aatataagta cgttatgcca tactgactgg taaaagtagc gatagcggct actgtcattg
    28861 cggatgcgaa ggctttgttg tatccacggt agcaacaaca ttgccatcag cagcagatag
    28921 cagccaaaat cccaaagcgc cttttcagct ctccaggggg tcatgccatc agtttgccac
    28981 ttcagcaagc cgctcattcc cagcgtggca ataaacacca gcgccagcca tccccaaagg
    29041 cgattctgtt taaaggagat cacggagaag agtaaaacgg atgaaaacgc gacggtcgca
    29101 ggcacgccat aaacaatcca actgagattt tttccggcaa gccaggcgat cagcaggtag
    29161 caaaccagcc cctgaagtaa tccggtagca atcatccccc agcgtgttgc cggtgaaagt
    29221 tcaacgttat ccatgttggt tatccagaat caaaaggtgg gttaattatc gcatcgggca
    29281 gtagtatttt gcttttttca gaaaataatc aaaaaaagtt agcgtggtga atcgatactt
    29341 taccgattga atttgcatca atttcattca tgaatgcggt tccactcaca atattcccgc
    29401 catataaacc aagatttaac cttttgagaa cattttccac acctaaaatg ctatttctgc
    29461 gataatagca accgtttcgt gacaggaatc acggagtttt ttgtcaaata tgaatttctc
    29521 cagatacgta aatctatgag ccttgtcgcg gttaacaccc ccaaaaagac tttactattc
    29581 aggcaataca tattggctaa ggagcagtga aatgcgcgtt aacaatggtt tgaccccgca
    29641 agaactcgag gcttatggta tcagtgacgt acatgatatc gtttacaacc caagctacga
    29701 tctgctgtat caggaagagc tggacccgag cctgaccggt tatgagcgcg gggtgttaac
    29761 taatctgggt gccgttgccg tcgataccgg gatcttcacc ggtcgttcac cgaaagataa
    29821 gtatatcgtt cgtgacgata ccactcgcga tactttctgg tgggcagaca aaggcaaagg
    29881 taagaacgac aacaaacctc tctctccgga aacctggcag catctgaaag gcctggtgac
    29941 caggcagctt tccggcaaac gtctgttcgt tgtcgacgcc ttctgtggtg cgaacccgga
    30001 tactcgtctt tccgtccgtt tcatcaccga agtggcctgg caggcgcatt ttgtcaaaaa
    30061 catgtttatt cgcccgagcg atgaagagct ggcaggtttc aaaccagact ttatcgttat
    30121 gaacggcgcg aagtgcacta acccgcagtg gaaagaacag ggtctgaact ccgaaaactt
    30181 cgtggcgttt aacctgaccg agcgcatgca gctgattggc ggcacctggt acggcggcga
    30241 aatgaagaaa gggatgttct cgatgatgaa ctacctgctg ccgctgaaag gtatcgcttc
    30301 tatgcactgc tccgccaacg ttggcgagaa aggcgatgtt gcggtgttct tcggcctttc
    30361 cggcaccggt aaaaccaccc tttccaccga cccgaaacgc cgcctgattg gcgatgacga
    30421 gcacggctgg gatgatgacg gtgtgtttaa cttcgaaggc ggctgctacg cgaaaactat
    30481 caagctgtcg aaagaagcgg aacctgaaat ctacaacgct atccgtcgcg atgcgctgct
    30541 ggaaaacgtc accgtgcgtg aagatggcac aatcgacttt gatgatggtt caaaaaccga
    30601 gaacacccgc gtttcttatc cgatctatca catcgataac atcgttaagc cggtttccaa
    30661 agcgggccac gcaactaaag ttattttcct gacagcagac gcctttggtg tgctgccgcc
    30721 ggtttctcgt ctgactgccg atcaaaccca gtaccacttc ctctctggct tcaccgccaa
    30781 actggctggt acagagcgcg gcatcaccga accgacgcca accttctccg cttgcttcgg
    30841 cgcggcgttc ctgtcgctgc acccgaccca atacgcagaa gtgctggtga aacgtatgca
    30901 ggcagcgggt gcgcaggcgt atctggttaa caccggctgg aacggcactg gcaaacgtat
    30961 ctccattaaa gatacccgcg ctattatcga cgccatcctc aacggttcgc tggataacgc
    31021 agaaaccttc actctgccga tgtttaacct ggcgatccca accgaactgc cgggcgtaga
    31081 cacgaagatc ctcgatccgc gtaacaccta cgcttctccg gaacagtggc aggaaaaagc
    31141 cgaaacgctg gcgaaactgt ttatcgacaa cttcgataaa tacaccgaca cccctgcggg
    31201 tgccgcgctg gtagcggctg gtccgaagct gtaatgattt gaagctggag aatatctatc
    31261 cagtatctta tagaaagcaa aacgggaggc accttcgcct cccgttttat ttacccttct
    31321 tttgtcgtgc cctgcgcccg cgttaccggc actggcagcc aggcgcgaat ggaaagcccg
    31381 ccccgttcgc tggtgccaag ctccagcatc ccgttatggt tatccacgat acgctgcaca
    31441 atcgccagcc ctaatcccgt gccgctaata gtgcgcgcac tgtcgccacg aacaaacggc
    31501 tggaacaggt gcttacgttg ttccggcgca atacccggac cgtcatcttc tacctggaac
    31561 caggcgcgat tcggctccgt gccgctgctg actttgatcc agccattgcc gtaacgggcg
    31621 gcgttgacca ccatattcgc taccgcgcgt ttgatcgaca gcgggtgcat tttcacctca
    31681 atgctgccgg ggtaaagcgc agtttcaatt tcccgctcat agccactttc ggcagcaata
    31741 acctcaccga gtactgcgtt gagatccgcc atttccatcg gcatctcctg cccggtgcgc
    31801 aggtagtcga taaactgctc aatgatggcg ttgcactctt cgatatcttt attgatcgat
    31861 tctgccaggt agccatcctg ctcgctcatc atctcggttg ccaggcgaat acgcgtcagc
    31921 ggcgtgcgca gatcatggct tacccccgcc atcagcagcg tgcggtcatc cgccagttgc
    31981 ttaacaccag ccgccatatg attaaaggcg cgggtaacgg aacgcacctc cgaagcgcca
    32041 tattcacgca gcggcggcgg aataatccct ttacccacct gcaaggctgc gtgttcgaga
    32101 tcgaccaacg gtcggttctg gatacgaata aacagccacg ccccgcctat cgccaatagc
    32161 ataatcgcca acgtataacg gaacagcggg gagaaatcgc cctgatgaat ttcggttagc
    32221 ggcacgcgta cccagatatt gggagacaac caggttttca gccagacgac aggcgaactt
    32281 ttgttaacct cgacgcgaac ttccgtcgga ccgcccagtt gctgcgccat ctgatggctt
    32341 aagaattcat agtgttgcgc ccaacgcagc ccggcctctt cggcggcttc gttggaatag
    32401 agagagatcc ccagctcacg gtagatctcc cgacggaaag cgggaggcac aaccaactgc
    32461 gtgccgtcct ccagttgcag tttgtcggtc atcaacatac gcacttcgta cgcgaggact
    32521 ttattaaact gctggaggct cggcaaaatc gcgaagttca gcaccaccag ataagtcgtc
    32581 accaggctga caaacagcaa ggtgacgatg agcaataacg tacgggcaaa tgaacttcgt
    32641 ggcgagaagc gcaatcgcct catgctttag aaccgtccgg tacaaagacg tagcccagac
    32701 cccagacggt ctgaatgtaa cgcggatgcg ccggatcttc ttccaccatg cggcgcagac
    32761 gcgaaatctg cacgtcgatg gagcgttcca ttgcggaata ttcacgacca cgggcaaggt
    32821 tcatcagctt atcgcgggag agcggctcac gcggatggct gaccagtgcc ttcagtaccg
    32881 caaactcacc actggtgagc ggcatcggct cgtcttcgcg gaacatttcg cgcgtaccga
    32941 ggttaagttt gaacttaccg aaagcaatta ccgcctcttc ctgtgacggt gcgcctggca
    33001 gttcgttcgc ctgacgacgc agcaccgcac gaatgcgggc cagcagttca cgcgggttaa
    33061 acggttttgg aatgtaatcg tcagcgccaa tctccaggcc aacgatacgg tccacttctt
    33121 cccctttcgc cgtcaccata atgatcggca tcgggttact ctggctacga agacgtcggc
    33181 aaatcgacaa gccatcttca ccaggtaaca tcaaatccag taccataaga tggaaagatt
    33241 cacgagtcag caggcgatcc atctgttctg cattagcgac gcttcgaacc tggaagcctt
    33301 gttcggtgag ataacgttcc agcagcgcgc gcaggcgcat gtcgtcatca accaccagaa
    33361 tcttgtagtt ctcttgcatt gtttgtactc ccaaaggttc gcaacaattt gtaagcgtgt
    33421 attcttaaaa aagctcacgt tcgtcaccag ctaaatctgg tatgaatttc agcctaaatt
    33481 gttacaaagc atattaaaca gcagcttaag tatacaattt attcggcgaa acattattga
    33541 ttctgttgat atgatcacgt tatacccaat gtgcgcatta tcaaacagac aaagggaatc
    33601 aacgagatga aaacgcccct ggttacccgg gaagggtatg aaaaactcaa acaagagctt
    33661 aattatctct ggcgtgaaga acgcccggag gtcacaaaga aagtgacctg ggccgcaagt
    33721 ctgggcgacc gcagcgaaaa tgctgactat cagtataata aaaagcgcct gcgtgaaatc
    33781 gaccgtcgcg tgcgctatct cactaaatgc atggaaaatc tcaaaatcgt cgattactcc
    33841 ccgcagcagg aaggcaaagt cttttttggt gcgtgggtgg agattgaaaa cgacgatggt
    33901 gtgactcacc gtttccgtat tgtcggctac gatgaaattt ttggccgtaa agattacatc
    33961 tctatcgatt ccccgatggc ccgcgcattg ctgaaaaaag aagtcggcga tctggcggtg
    34021 gtgaataccc ctgccgggga agcgagctgg tatgttaatg ctatcgagta cgtgaaaccg
    34081 taaggaagag tcttaacctc ctgccgatgg ctggcatttt tgccagccag tccgtataac
    34141 tatcccctga tttttgatcc gaaaagatga actcaaacca tgatgaatga ttcgttctgc
    34201 cgcattattg cgggtgaaat tcaggcgcgc ccggaacagg ttgacgctgc cgttcgcctg
    34261 cttgacgaag ggaataccgt gccgtttatc gcacgttatc gtaaggaaat caccggcggt
    34321 ctggatgaca cgcagctgcg taatctggaa acgcgtctga gctatctgcg cgagctggaa
    34381 gagagacgtc aggcgatcct caagtctatt tccgagcaag gcaaactcac cgatgatctg
    34441 gcgaatgcca tcaacgccac cctaagcaaa accgaactcg aagacctcta cctgccctac
    34501 aaacctaaac gccgcacccg tgggcaaatc gccattgaag cagggcttga gccgttggcc
    34561 gatctgctgt ggagcgatcc gtcacacacg ccagaagtcg ccgctgcaca atatattgat
    34621 gccgataaag gcgtggcaga taccaaagcc gcgctggacg gcgcgcgcta tatcctgatg
    34681 gaacggtttg ccgaagatgc cgcgctgctg gcgaaagtgc gtgattatct gtggaagaac
    34741 gcgcatctgg tctcaaccgt ggtgagcggt aaagaagagg aaggggcaaa attccgcgac
    34801 tatttcgatc atcacgaacc actgtcaacg gtgccttctc accgcgcact ggcgatgttc
    34861 cgtggtcgta acgaaggcat acttcagctt tcgctgaatg ccgatccgca gttcgaagag
    34921 ccgccgaaag agagctattg cgagcaaatc atcatggaac accttggcct gcgcctgaac
    34981 aatgccccgg cggatagctg gcgcaaaggt gtggtgagct ggacgtggcg catcaaggtg
    35041 ttgatgcatc tggaaactga actgatgggc accgtgcgcg aacgcgcgga agatgaagca
    35101 atcaacgtct ttgcccgtaa cctgcacgat ctgctgatgg cggcccctgc cggactgcgt
    35161 gcaacgatgg gcctcgatcc gggtctgcgt accggggtaa aagtggcggt agtcgatgca
    35221 actggtaaac tggtggcgac cgataccatt tatccgcata ccgggcaggc cgcaaaagca
    35281 gcgatgaccg ttgctgcgct gtgtgaaaag cataacgttg aactggtggc gatcggcaac
    35341 ggtacagctt cccgcgaaac cgaacgtttc tatctcgacg tgcagaagca gttcccgaaa
    35401 gtgaccgcgc agaaagtgat cgtcagcgaa gctggcgcgt cggtttactc ggcttccgag
    35461 ctggcagcac aggaattccc ggatctcgac gtttcgctgc gtggcgcggt gtctatcgcc
    35521 cgtcgtttgc aggatccgct ggcggagctg gtgaaaatcg atccgaaatc tatcggcgta
    35581 ggtcagtatc agcatgacgt cagccagacg cagctggcac gcaaactgga tgcagtagta
    35641 gaagactgcg taaacgccgt tggcgtcgat ctcaacaccg cttctgttcc tctgttaacc
    35701 cgcgtggcgg gcctgacgcg catgatggcg caaaacatcg tagcctggcg cgatgagaac
    35761 ggtcagttcc agaaccgtca gcaactgtta aaagtgagcc gtctggggcc gaaagccttc
    35821 gagcagtgcg cgggcttctt gcgcattaac cacggtgata acccactgga cgcttctacc
    35881 gttcacccgg aagcctatcc ggtggtggaa cgcattctgg cagcaacaca gcaggcactg
    35941 aaagatctga tgggtaacag cagcgaactg cgtaacctga aagcgtctga ctttactgat
    36001 gagaaattcg gtgtgccgac ggtaaccgac atcatcaaag agctggaaaa accgggtcgc
    36061 gatccgcgtc cggaatttaa aaccgctcag tttgccgatg gtgtcgagac aatgaacgac
    36121 ctgcaaccgg gtatgatcct cgaaggtgcg gtgaccaacg tcaccaactt tggcgcgttt
    36181 gtcgatattg gcgtgcatca ggacggcctg gttcacatct cttcattgtc gaacaagttt
    36241 gtggaagatc cgcataccgt ggtgaaagcg ggcgacattg tgaaggtgaa agtgctggaa
    36301 gtggatcttc agcgtaaacg tatcgccctg accatgcgtc tggacgagca gcctggcgaa
    36361 accaacgccc gtcgcggcgg cggtaatgaa cgcccgcaaa acaaccgccc ggcagccaaa
    36421 ccgcgtgggc gtgaagtgca gcctgccggt aacagcgcga tgatggatgc gctggcggcg
    36481 gcaatgggca aaaaacgtta aacgcccgga ctggccccta aacctgcgcg attaggcgtt
    36541 cacgccacat ctggcaacga acgccttgcc tgacataaaa gtgccggaga atatctccgg
    36601 cctttttatt ccacaagcaa acgcataata tatcccgtta atatttatca cttcattaac
    36661 aactgaaacc ttaattaaac attaaccagc cctaataatt cgtcatgcga attatatttt
    36721 cgctgcgata taagcttgag ccatatcaac attgagtcag attattattc aaaccaacat
    36781 tcacacacat tttaagtatt gctgatagaa accattctca ttatcattgt actgttgatt
    36841 atttaatctc tccttcgttg gcaaatcatc tggtctcatg tcgctgtcaa acgccccatg
    36901 aggtagttat ccagttaatg agaaacaagt aggcacctat gcaatacact ccagatactg
    36961 cgtggaaaat tactggcttt tcccgtgaaa tcagcccggc atatcgccaa aaactgcttt
    37021 ctcttggcat gttacctggc tcctctttta atgtggtgcg cgtcgctcca ctcggcgacc
    37081 ccattcatat cgaaacccgt cgtgtgagcc tggtattacg caaaaaagat ctggccttat
    37141 tagaagtgga agcggtttcc tgttaatacg gtgataacaa caatgaaaaa attaaccatt
    37201 ggcttaattg gtaatccaaa ttctggcaag acaacgttat ttaaccagct tactggctca
    37261 cgtcagcgtg taggtaactg ggctggcgtt accgtcgaac gtaaagaagg gcaattctcc
    37321 accaccgatc atcaggtcac gctggtggac ctgcccggca cctattctct gaccaccatc
    37381 tcatcgcaga cctcgctcga tgagcaaatc gcctgtcact acattttgag tggcgacgca
    37441 gacctgctga ttaacgtggt ggatgcgtct aaccttgagc gtaacctgta cctgacgctg
    37501 caactgttgg aactcggcat tccctgcatc gtggcgctga acatgctcga cattgccgag
    37561 aagcaaaata ttcgtattga aattgatgct ctgtcggcgc gtcttggctg cccggtgatc
    37621 ccgctggttt caacccgtgg tcgcggtatt gaagcgctca agctggcgat tgatcgctat
    37681 aaagctaacg agaatgtgga actggtgcat tacgctcagc cgctgctcaa cgaagcagat
    37741 tcactggcaa aagtgatgcc ttccgacatc ccgctgaaac aacgtcgctg gctgggcctg
    37801 caaatgctgg aaggcgatat ctacagccgc gcctacgccg gtgaagcgtc gcagcatctg
    37861 gatgccgccc tcgcccgtct gcgtaatgag atggacgatc cggcgctgca cattgccgat
    37921 gcgcgttacc agtgcattgc tgccatctgt gatgtggtaa gcaacaccct gacggcagaa
    37981 cccagccgtt tcaccactgc ggtagataaa atcgtgctca accgtttcct cggtctgccg
    38041 attttcctct ttgtgatgta cctgatgttc ttgctggcta tcaacatcgg cggggcgtta
    38101 cagccgctgt ttgacgtcgg ctccgtagca ctctttgtgc atggtattca gtggattggc
    38161 tacacgctcc acttcccgga ctggctgact atcttcctcg cccaaggcct gggcggcggt
    38221 attaacaccg tgctgccact ggtgccgcag atcggcatga tgtacctgtt cctctccttc
    38281 cttgaggact ccggctatat ggcgcgtgcg gcgtttgtga tggaccgtct gatgcaggcg
    38341 ctgggcttgc cggggaaatc ctttgtaccg ctgatcgttg gtttcggttg taacgtaccg
    38401 tcggtaatgg gcgcacgtac gcttgatgca ccgcgtgaac gtctgatgac catcatgatg
    38461 gcaccgttta tgtcctgcgg cgcgcgtctg gctatcttcg cagtattcgc ggctgccttc
    38521 ttcgggcaga acggtgcgct ggcggtcttc tcgctgtata tgctgggtat cgtaatggcg
    38581 gtgctgactg gcctgatgct caagtacacc atcatgcgcg gtgaagcgac gccgtttgtc
    38641 atggagctgc cggtctacca tgtaccccac gttaaaagcc tgattatcca gacctggcag
    38701 cgtctgaaag gcttcgttct gcgtgctggt aaagtgatta tcatcgtcag cattttcctg
    38761 agcgccttca acagcttctc attgagcggg aaaatcgtcg ataacatcaa cgactcggcg
    38821 ctggcttccg tcagccgggt gatcaccccg gtcttcaagc cgattggcgt acatgaagat
    38881 aactggcagg caacggttgg cctgtttaca ggtgccatgg cgaaagaagt ggtggtgggt
    38941 acgctcaaca ccctctacac cgcagaaaat attcaggacg aagagttcaa tccggcggaa
    39001 tttaacctcg gtgaagagct gttcagtgcg gtagatgaaa cctggcagag cctgaaagac
    39061 accttcagcc ttagcgtact gatgaacccc attgaagcaa gcaaaggcga cggcgaaatg
    39121 ggtaccggag cgatgggcgt gatggatcag aaattcggta gcgcagctgc cgcatacagc
    39181 tacctgattt tcgtcctgct gtatgtacca tgtatctcgg tgatgggagc catcgcccgt
    39241 gaatcaagcc gtggctggat gggcttctcc attctgtggg ggctgaatat cgcttactcg
    39301 ctggcaacat tgttctatca gatcgccagc tacagccagc atccaaccta cagcctggta
    39361 tgcattctgg cggttattct gtttaacatc gtggttatcg gtttgctgcg tcgcgcgcgt
    39421 agccgggtgg atatcgaact gctggcaacg cgcaaatcgg taagcagttg ctgtgcggcc
    39481 agtaccactg gcgattgcca ctaaggacac gacaatggct tcgctcattc aagtgcgtga
    39541 tttactggca ttacggggcc gtatggaagc ggcccagatt agccagacac tgaacactcc
    39601 gcagccaatg attaacgcca tgctgaaaca gctagaaagt atgggaaaag cagtgcggat
    39661 tcaggaagaa cctgacggct gtctttccgg cagttgtaaa agctgcccgg aaggaaaagc
    39721 ctgtctgcac gaatggtggg cgttgcgtta accttgtttc actgcctgtt ttgaaagccc
    39781 ggtatgcgtt tgcatccggg cttttttgcg tgcggctttc catagcagcg cgacgtaagt
    39841 tcctctgaaa gcgtctcgct gggatgaaaa ctcgctaatg cacaggtgtg gagtggcgcg
    39901 tagagtcgcg gcattcaaat aacaggtgaa ggaacgccat gagcaaaaag cagagttcca
    39961 ccccacacga tgcgctgttc aaactctttt tacgccaacc ggagacggca cgcgagcatg
    40021 gcgctgctgg agttaattca aaaacatatt cgtcaacgcg atctgatagg actggtagag
    40081 caaatggcct gcttattaag tagtggatac gcaaatgaca gacaaatcaa agggctgttt
    40141 aattacatac tgcaaaccgg cgacgcggta cgttttaacg attttatcga tggtgtggcc
    40201 gaacgttcac caaaacacaa ggagagttta atgactattg cggaaagatt gcggcaggaa
    40261 ggggaacaat ccaaagcctt gcatatagca aaaataatgc ttgaatccgg agtccctctt
    40321 gcagacatca tgcgctttac cggggtgtca gaagaagagt tggctgcggc gagccagtaa
    40381 agttctgtcc cgccatttcg aaagccacct acaccctctg cttcaacgcc accagcaggt
    40441 gacaaaactc gtccggatgt gaaataaacg gcgcatgggc cgctttggcg aagatatatg
    40501 attcgctgtg aggccaaagt ttatccagca tcggcaccac tttgcgcggc accagaccgt
    40561 cgagatagcc atacaatcgc aaaaacggca tgggcacgtt ttgcagcggc tgacggagat
    40621 cgaccgtttt caggatttcc agtccgccat tgagtacgtc aacctccggc atcggtaacg
    40681 ccagaacggt tttcttcaac gcccgcgcat cctggcgcgc cgtttcagta cccatggttt
    40741 gtaacgccag gaaccgctcc actgtacgct gaaaatcatc actgagttgc tgctgaaatc
    40801 ccgccagcac gtccggtttt atccccggcc actcgtcgcg agcactaaaa caaggtgacg
    40861 acgccacggt gaccagcgcc tgaacacgct cgggatgggt taacgcaatc tggcttgcca
    40921 ccagcccgcc cagactccag cctaaccaaa tggctttatc tggtgcctgt cgcagcacga
    40981 cttcggccat atcagcaagt gatagcgcac caaatccccg gctacgcccg aagccgggca
    41041 ggtcaacaag gtgcagcgta aaatgcgagc taagttcctc gtcaatgcaa cgccacactt
    41101 cggcattcag tccccatccg tgcagcagca caagatgaac attcccctga cctttggtct
    41161 gccaccagat gttattcatc cgctattgtt ctctttttac ttacaaggat gaacatatgc
    41221 taacagtacc gggattatgc tggctatgcc gaatgccgct ggcgttaggt cattggggga
    41281 tttgttctgt ctgctctcgc gccgcccgta cagataaaac gttatgccca caatgtggat
    41341 tacccgccac acactctcat cttccctgcg gtcgctgcct gcaaaaaccg ctgccctggc
    41401 aaagactgct cacggtcgcc gactatgcgc cgccattaag tccgctcatt caccagctta
    41461 agttttcccg gcgcagtgaa atcgccagcg ccctgtcacg tctgttacta ttggaagtct
    41521 tacacgctcg tcgcaccacc ggcttgcaac tgcctgatcg catcatcagc gttccgttat
    41581 ggcagcgccg tcactggcgt cggggattta atcagagcga tttgctgtgt cagccgttat
    41641 cacgctggct acactgccaa tgggatagcg aagccgtcac acgaacacgg gccaccgcga
    41701 cccagcattt tcttaacgcc cggctacgca aacacaacct gaaaaatgcc tttcgccttg
    41761 aattgcctgt gcaaggtcgc catatggtga ttgtggatga tgtcgttacc accggaagta
    41821 ccgtcgcaga gattgcgcag ttgcttttac gcaatggtgc ggcgactgtc caggtctggt
    41881 gcctttgtcg aaccttgtag agcctcgatg atgggcgtat tataaccaac taaaatagtc
    41941 aactattagg ccattactat gatccgtatt tccgatgctg cacaagcgca ctttgccaaa
    42001 ctgctggcaa accaggaaga agggacacaa atccgcgtat ttgtgattaa ccctggcacg
    42061 cctaacgctg aatgtggcgt ttcttattgt ccgccggacg ctgtggaagc caccgacact
    42121 gccctgaaat ttgacctgct gaccgcgtat gttgatgagt taagcgctcc ttacctggaa
    42181 gatgcagaga tcgattttgt taccgaccag ttgggttcgc agctgacgct gaaagcgcct
    42241 aacgccaaaa tgcgtaaagt ggctgacgat gcgccgctga tggagcgcgt ggagtatatg
    42301 ctgcaatcac agatcaaccc acagcttgct ggtcacggtg gtcgcgtttc gctgatggaa
    42361 atcaccgaag acggttacgc cattttgcaa tttggcggtg gctgtaacgg ttgttccatg
    42421 gtcgacgtca ccctgaaaga ggggatcgag aagcagttgc tgaacgaatt cccggagctg
    42481 aaaggtgtac gcgatctcac cgaacaccag cgcggcgagc actcttacta ctaagttctc
    42541 tccccttttg tcgattgccc gatgtgacgc taaagcgtct tatcgggcct gtacgttgca
    42601 cgagagtctg acgttagcgc agaattatct cagcaaatcc aatctcttcg tttccccacg
    42661 ataatatgac caacctctca taatttaaat ttaccccgct ctggtgattc tcaagcacgt
    42721 aatgttaccc gtatcattct catgggcacc aaacacactc ataacatctg actacactaa
    42781 ctcgttttag gggtcatcag ccgtggtgcc gtaacatctc tgttcccagt tgggacaacc
    42841 aggattttcc gtcagaaacc tgacgttacc cataacaaat taaaggccag gtaaatcatg
    42901 ccattagtca ttgttgctat cggtgtaatc ttgttattac tcctgatgat ccgcttcaaa
    42961 atgaacggct tcatcgctct cgtcctcgtg gcgcttgctg ttggattaat gcaagggatg
    43021 ccgctggata aagttattgg ctccatcaaa gctggtgtcg gcggaacgct cggtagcctt
    43081 gccctgatca tgggttttgg tgcgatgctg ggcaaaatgc tggcagactg cggtggtgca
    43141 caacgtatcg ctaccacgct gattgccaaa tttggtaaaa aacacatcca gtgggcggtg
    43201 gtactgaccg gttttaccgt tggttttgcc ctgttctatg aagtgggttt cgtgctgatg
    43261 ctgccgctgg tgtttaccat cgcggcttcc gcgaatattc cactgctgta tgttggtgta
    43321 ccaatggcgg ctgcactgtc tgtgacccac ggcttcctgc caccgcatcc gggtccgact
    43381 gcgattgcca ccattttcaa tgccgatatg ggtaaaactc tgctgtacgg tactattctg
    43441 gcaatcccga ccgtgattct cgccggtccg gtttacgctc gcgtgttgaa aggtatcgat
    43501 aagccgatcc cggaaggtct gtacagcgcg aaaaccttca gcgaagaaga gatgccgagc
    43561 tttggcgtca gcgtctggac ctctctggtg ccggtggttc tgatggcgat gcgtgcgatt
    43621 gccgaaatga tcctgccgaa aggtcacgct ttcctgccgg tagcggagtt cctcggtgac
    43681 ccggtaatgg ctacgctgat tgccgtgctg atcgcgatgt tcacctttgg tctgaaccgt
    43741 ggccgttcaa tggatcagat taacgacacg ctggtttctt ccatcaaaat cattgcgatg
    43801 atgctgttga ttatcggtgg tggcggtgcg ttcaagcagg tgctggtaga cagcggcgtg
    43861 gacaaataca ttgcttccat gatgcacgaa accaacattt ctccgctgct gatggcctgg
    43921 tcgattgctg ccgtactgcg tatcgcgctg ggttccgcaa ccgtcgcggc aatcactgcg
    43981 ggtggtatcg cggcaccgct gattgcaacg acgggtgtta gcccggagct gatggttatt
    44041 gcggttggtt ccggtagtgt gattttctct cacgtgaacg atccgggctt ctggctgttc
    44101 aaagagtact ttaacctgac tatcggcgag accatcaaat cctggtcgat gctggaaacc
    44161 attatctcgg tgtgcggtct ggtaggctgt ctgctgctga atatggtgat ttgataatac
    44221 tgatggccgg atgcggcgtg aacgccttat ccggcctacg attcggcatt aattagtagg
    44281 ccggtaagac gcgtcaagcg tcgcatccgg catcaaccgc actctacttc ttcttcgctg
    44341 ccgctctgcg ccgtctgtcc aaatccttca gcaacttgtt cacaccatca tcggcaaaca
    44401 tcgactcaag cgttgcggaa agtttacgtc gccagttttt atactggtaa ctggtgccgg
    44461 gaatatttac cggatctgcc atatccagcc agtcttccgg ctggagccct aacagggcgc
    44521 tgttgctatc ggcgatgtag cgctgtaagc cacgattcag cgtcggtgtc atcgacatca
    44581 acgatgcctt atgcccggca cgttttggca ggcaaccata tttatgcaga gcatccagca
    44641 gcccttgctt cgccagttcg cgatcctgat acagaccgcg cagtaccact tcatccggat
    44701 acagccccag cgttttgccc agcgttaaat ccccactctc ccagtagccg cgtagcgtag
    44761 gcaggtcgtg tgtcgccgca accgccatcg actgctctgg gtacgctttc ggtgcgcgga
    44821 atgtcttctc gtggtcgttt tcgaaataga gcactttgta ggagtacaca ccgctgctgc
    44881 gcagcttacc gacaatctct accggtacgg taccgagatc ttcaccaatc accatacagc
    44941 gatgacgttt actttcgagt gccagaatcg agagcagatc atccaccgga tagtgaacat
    45001 acgcgccctg atctgccgtc tcgccatacg gtatccacca caaacgcagc atcgacatca
    45061 cgtgatcaat tcgtaatgcg ccgcagtttt gcatattggc acgcaacagc tcgataaacg
    45121 gttcataggc acgcgcggtg atgatatgcg ggtccattgg cggcaatccc cagttctgcc
    45181 ccaacgggcc gaggatatcc ggcggcgcgc caaccgacgc tttcaggcaa tacagttcac
    45241 ggtcgcacca ggtttctgcc ccaccttctg ctacaccaac ggccagatca cgatacaagc
    45301 caatcggcat ttcatagccc tggcttatct cccagcaggc ggcaaactgg ctgtaagcca
    45361 gccactgcaa ccagagataa aaatcgacgt catcacgatg ttcttcgcag aactggcgca
    45421 cttctggcga atccacgttc tgatacatct ctggccatgc tggccagccc cagcgcattt
    45481 cgtcctcttt cacttgctgg gcatgtagcg catcaaaggc tgcctgccag aacaggctgt
    45541 cgccctgctc tgcaacaaac tggcgaaacg cggtcatctg ctcatcatca cgttgcgcga
    45601 aacctttcca cgccattcgt aatgctgtca tttttagggc ggtaaccgtg gagtaatcaa
    45661 cccagtcggc atcccgcgcc tgttgcagcg tctgttgcgt ggtcggcaac tgccaccagg
    45721 cctgagcctc ttcgctaaga tggaaatctt caactgcgtt aacgtcgata taaatcacat
    45781 tcagccaacg gcgagaagac gggctgtacg ggctggcact ttccggattt gccagataga
    45841 gcgcatgaat cgggttcaga ccaataaacg acccgccacg ttttgccaca tccaccagca
    45901 tcgctttgag atcgccaaaa tccccaatac cccagttttt ttccgatcgc agcgtataaa
    45961 gctgaacgca ggcaccccac agcttttgtt tattcagcaa cgcctgcggt tcgtaacagc
    46021 gtttcggggc gacaatcacc cggcaatgcg cgcgctggtc gtcctgggta agcgtcagcg
    46081 tgtgataacc ttccggcagc ttcgtcggta gattgaacgc tttgcccccc gtcacatggc
    46141 ctttgtactg ctttccttct tcggtggtca gcagccagct atattcgccg ctgccctcca
    46201 ccaccatcgg catttttttg ccgctggtat aaactatgac attcgggact ggcgttaccg
    46261 ccactttcgt ggcggtacgt tgatgcatcg cgtcaagcaa acgccgtttg gtttcggcgc
    46321 taatcgactg cggtttaccg tgggcattga tgtaattggg gctaatcccc gccgccagcg
    46381 cggcattatc cagacgtttg ctttccatcg aacttcctta gcgttttgcc tgccagatac
    46441 gagcctgata atcgcgaata gagcgatccg agctaaacat accgcagcgg gcggtattga
    46501 ggatcgccgc gcgagtccag gcctcctggt cgcggtacag cacatccacc tgcttttgtg
    46561 cctccacata agcggcgaaa tctgccatca ccagatacgg atcgccgccc tgtttgccga
    46621 tactgtgcag catctggtcg aaggcatgct tatcgccgtc gctgtattta ccgctttcca
    46681 gctctttcaa tactgcgtcc agcaccttat ctttcttccg ccatttcacc gggtcgtagc
    46741 ctttggccag aattgccttc acttgttcca cggtatgacc aaaaataaag atattttctt
    46801 cgccgacttt ctcagcgatt tcaacgttcg caccatccag cgtaccgaca gtaagcgcac
    46861 cattgagcgc cagtttcata ttgccggtac cggaagcttc tttacctgca gtcgaaattt
    46921 gttcggagat atccgccgcc gggatcagtt tttccgccgc cgaaacacaa taatccggca
    46981 agaacaccac cttcaacttg tcgccaacca gcggatcgtt gttgatcacg tcagccactt
    47041 tgttgatcgc aaagataata tttttcgcca ggtagtagcc cggtgctgct ttcgcgccga
    47101 agaggaagac gcgcggtacg cggtcagact gcgggttttc acgaatttct ttgtacaacg
    47161 ccagaatatg cagcagattc agatgctggc gtttgtactc atgcagacgt ttgatctgaa
    47221 tatcgaaaat cgcctgtgga ttgatctcaa taccggtacg aactttcaca aactctgcca
    47281 gacggacttt attcgcctgc ttgatctcgc gatattgctg acggaatttc gcatcatcag
    47341 cgaatttttc cagattgatc agttgatcga gatcgttagc ccactctttt ttcagtgatt
    47401 tatccaacag agccgccagt gccgggttgc actgtttgac ccagcgacgt ggggtaatac
    47461 cgttggtgac attatggaat ttgttcggcc atagctggtg atattccggg aacagatctt
    47521 tcaccaccag atccgagtgc agcgccgcaa caccgttcac cgcgaaaccg ccaaccacac
    47581 acaggttcgc catatgcact tgtttgtcgt gcaccaccgc cagtttggcc cacacttttt
    47641 catcgcccgg ccaggttttc tccactagcg ttttaaagcg agtattaatt tcgttaataa
    47701 tctgcatgtg gcgcggcagt aagcctttca ccagtttcac atcccagcgt tccagcgctt
    47761 ctggcatcag ggtatggttg gtgtaagcga aagttttgct ggtaatggcc caggcgtcat
    47821 cccagctcat ctggtgctca tcgatcagca cgcgcagcag ttctggaatc gcgattgttg
    47881 gatgggtatc gttcagctga ataacttcgt aatccgccag ttcgtgcaat ttacgccccg
    47941 ccagatgatg gcgacgcaaa atatccgcta ccgagcaggc acactggaag tattgctgca
    48001 tcaggcgcag ctttttaccg gcagtatggt tgtcgtttgg atagagaact ttggtcagtt
    48061 tttctgcgtt gatgccctgc tgttcggcac gcaggaaatc accatcgtta aatttagtca
    48121 gatcaaacgg atgcgcatgc gtcgcctgcc acagacgcag cggctgcgcc acgccattac
    48181 gatagccgac aacggggaga tcccacgctt gaccggtaat ggtaaattcc ggctcccagc
    48241 gtccgtcttt cgtcacttta ccgccaatcc ctacctgcac atccagtgct tcgttgtggc
    48301 ggaaccacgg gtagttaccg cgatgccagt catccggcgc ttcaacctgt ttgccatcga
    48361 caaaagactg gcggaacaaa ccatattgat agttcagacc gtaacccgtc gcagactgac
    48421 cgacagttgc cattgagtcg agaaagcacg ccgccagacg tcccagacca ccgttcccca
    48481 gcgccgggtc gatctcttct tccaacaggt cagtcaggtt gatgtcataa gccttcaacg
    48541 aatcctgtac atcctgatac cagccgagat tcaacagatt gttgcccgtc aggcgaccaa
    48601 tcaaaaactc cattgagatg tagttaacat gccgctgatt cgccaccggt ttggcaaatg
    48661 gctgagcacg cagcatttcg gccagtgctt cgctcactgc cagccaccac tgacgagggg
    48721 tcatttcagc cgcagaattt aagccataac gctgccactg acgtgaaagc gcttcctgaa
    48781 attgcttatc gttaaaaata ggttgtgaca taggagttcc acttttctta gattttcaac
    48841 acaacgttat cgctagtttg ccaggctcga tgttgacctt cctcatcctg cgggggatta
    48901 ggcagggagg agttgcgggg atgagcaagg aaatgtgatc tcgaccactt aaagctagtg
    48961 caatccacag gattagcagc aaatcaatgc cataccgcgc agaaaatctg tatctaagtg
    49021 caaaaaatgg ccgttgcgta ttttcaaaaa gcggaaggta actctataaa ttaagtaaag
    49081 gagtgaaaca gtttcacaag taaaatatca cgtgtgctcc atctcattct taatagattt
    49141 attaagatca tctttttaga tggcactttc atcagaaatg aagaagaaac ccttgcttaa
    49201 atgaaactga tgaacataag gaaaataccg tacaacccag tattcacgct ggatcagcgt
    49261 cgttttaggt gagttgttaa taaacatttg gaattgtgac acagtgcaaa ttcagacaca
    49321 taaaaaaacg tcatcgcttg cattagaaag gtttctggcc gaccttataa ccattaatta
    49381 cgaagcgcaa aaaaaataat atttcctcat tttccacagt gaagtgatta actatgctga
    49441 ttccgtcaaa attaagtcgc ccggttcgac tcgaccatac cgtggttcgt gagcgcctgc
    49501 tggctaaact ttccggcgcg aacaacttcc ggctggcgct gatcacaagt cctgcgggct
    49561 acggaaagac cacgctcatt tcccagtggg cggcaggcaa aaacgatatc ggctggtact
    49621 cgctggatga aggtgataac cagcaagagc gtttcgccag ctatctcatt gccgccgtgc
    49681 aacaggcaac caacggtcac tgcgcgatat gtgagacgat ggcgcaaaaa cggcaatatg
    49741 ccagcctgac gtcactcttc gcccagcttt tcattgagct ggcggaatgg catagcccac
    49801 tttatctggt catcgatgac tatcatctga tcactaatcc tgtgatccac gagtcaatgc
    49861 gcttctttat tcgccatcaa ccagaaaatc tcacccttgt ggtgttgtca cgcaaccttc
    49921 cgcaactggg cattgccaat ctgcgtgttc gtgaccagct gctggaaatt ggcagtcagc
    49981 aactggcatt tacccatcag gaagcgaaac agttttttga ttgccgtctg tcatcgccga
    50041 ttgaagctgc agaaagcagt cggatttgtg atgatgtttc cggttgggcg acggcactgc
    50101 agctaatcgc cctctccgcc cggcagaata ctcactcagc ccataagtcg gcacgccgtc
    50161 tggcgggaat caatgccagc catctttcgg attatctggt cgatgaggtt ttagataacg
    50221 tcgatctcgc aacacgccat tttctgttga aaagcgccat tttgcgctca atgaacgatg
    50281 cactcatcac ccgtgtgacc ggcgaagaaa acgggcaaat gcgcctcgaa gagattgagc
    50341 gtcaggggct gtttttacag cggatggatg ataccggcga gtggttttgc tatcacccac
    50401 tgtttggtaa cttcctgcgc cagcgctgcc agtgggaact ggcggcggag ctgccggaaa
    50461 tccaccgtgc cgccgcagaa agctggatgg cccagggatt tcccagcgaa gcgattcatc
    50521 atgcgctggc ggcaggcgat gcgctgatgc tgcgcgatat tctgcttaat cacgcctgga
    50581 gtttgttcaa ccatagcgaa ctgtcgctgc tggaagagtc gcttaaggcc ctgccgtggg
    50641 acagtttgct ggaaaatccg cagttggtgt tattgcaggc gtggctgatg caaagccagc
    50701 atcgctacgg cgaagttaac accctgctgg cccgcgctga acatgaaatc aaggacatca
    50761 gagaaggcac catgcacgca gaatttaacg ctctgcgcgc ccaggtggcg attaacgatg
    50821 gtaatccgga tgaagcggaa cggctggcaa aactggcact ggaagagctg ccgccgggct
    50881 ggttctatag ccgcattgtg gcaacctcgg tgctgggtga agtgttgcac tgcaaaggcg
    50941 aattgacccg ctcactggcg ttaatgcagc aaaccgaaca gatggcacgc cagcacgatg
    51001 tctggcacta cgctttgtgg agtttaatcc agcaaagtga aattctgttt gcccaagggt
    51061 tcctgcaaac cgcgtgggaa acgcaggaaa aagcgttcca gctgatcaac gagcagcatc
    51121 tggaacagct gccaatgcat gagtttctgg tgcgcattcg tgcgcaactg ttatgggcct
    51181 gggcacggct ggatgaagcc gaagcgtcgg cgcgcagcgg gattgaagtc ttgtcgtctt
    51241 atcagccaca gcaacagctt cagtgcctgg caatgttgat tcaatgctcg ctggcccgtg
    51301 gtgatttaga taacgcccgt agccagctga accgtctgga aaacctgctg gggaatggca
    51361 aatatcacag cgactggatc tctaacgcca acaaagtccg ggtgatttac tggcaaatga
    51421 ccagcgataa agccgccgct gccaactggt tgcgtcatac ggctaaacca gagtttgcga
    51481 acaaccactt cctgcaaggt caatggcgca acattgcccg tgcacaaatc ttgctgggcg
    51541 agtttgaatc tgcggaaatt gtcctcgaag aactcaatga aaatgcccgc agtctgcggt
    51601 tgatgagcga tctcaaccgt aacctgttgc tgcttaatca actgtactgg caggccggac
    51661 gtaaaagtga cgctcagcgt gtgttgctgg acgcattaaa actggcgaat cgtaccggat
    51721 ttatcagtca ttttgtcatc gaaggcgaag cgatggcgca acaactgcgc cagcttattc
    51781 aactcaatac gctgccggag ctggaacagc atcgcgcaca gcgtattctg cgagaaatca
    51841 atcaacatca tcggcataaa ttcgcccatt tcgatgagaa tttcgttgaa cgtctgctaa
    51901 atcatccgga agtgccagag ctgatccgca ccagcccgtt gacccaacgt gaatggcagg
    51961 tcctggggct gatttactcc ggttacagca atgagcaaat tgcaggcgag ctggaagtgg
    52021 cggcaaccac catcaaaacg catatccgta atctgtacca aaaactcggt gtcgcccacc
    52081 gtcaggccgc ggtacaacac gcgcagaaac tgctgaagat gatgggatat ggggtgtgag
    52141 tttagccgga taatgcgtcg gatccggctt acatctttac atcattcaat gctaacccgc
    52201 gttacgccat ctgtttctat caaaccaaac cgcaccggca agaaacgctc caccacggcg
    52261 atattggtca gcagatgaca tgagggatgg gcgaccgtaa attctcccgc gcccgccagc
    52321 gccatcggta gcaccagttg gtcggcgaga tattccccca ccgccgccgg gcttgccagg
    52381 tagcgtttca cctctttcac caactgtgcc gcgaccacct cggcactgac gcgcttttca
    52441 ccgacgacaa aaaagcgttc ggtgatattt tcactttcga cttcaagcga gacggtatta
    52501 cccggcccct ggtcgcgcgg caggttatga atattctgtt catgcaagga aaaactaccc
    52561 gccagtgtag cgatttcacg ctcagcaaca tggcgcggta actttcgcga actttctgcc
    52621 agcgtcacgc ggatggccac ctttgccact agcggacgca tcacactgga tacagtggaa
    52681 gatgagatca accgtctgcg ctataactgg caggagagtc gcccctccac gcttacggcg
    52741 ttgctgggcg cagaggcaga aaacatcgat ctcttcgacc gtatgcaact ggaacacgtt
    52801 atcgctatct gccgccaggc aaagtcgctt tctgctgccg gacgtgaact gtttgacatt
    52861 tcgcgccagg gtaaagccag cgtcaatgac gcggatcggc tacgcaaata cctggcgcgt
    52921 tttggtctga catgggaagc aatgcaggat cagcacagct ccagttgaat atgatggtcc
    52981 ttcagcacct gcatcacgct cgcaggcggc atcgtgtcgg tgtagacagc atcgaccatg
    53041 ctgatgctac ccatattgac cattgcgtta cggccaaatt ttgagtggtc gacaaccagc
    53101 ataacgtggc gcgagttctc aatgatggcg cgtttggtgc gaacttcgtg gtaatcgaac
    53161 tccagtagcg agccgtcgct atcgatgccg cttatcccca gaatgccgaa atcaaggcgg
    53221 aactgggaga taaaatcgag cgttgcttcg ccaatgatcc cgccatcgcg gctgcgtaat
    53281 tcgccaccgg caagaatgat acggaaatcc tcttttacca tcagcgtgtt agcgacgttg
    53341 agattgttgg tcacaatgcg taaattgctg tgattaagca gcgcgtgcgc caccgcttcc
    53401 ggcgtggtgc cgatatcgat aaacagcgtc gagccattgg gaatttgctc cgccactttg
    53461 cgggcgatgc gctctttttc ttcggtctgg gtggccttgc gatcgtgcca cggcgtgtta
    53521 accgaactgg aaggcagcgc cgcaccgcca tgatggcgca ggatcaggtt ttgctctgcc
    53581 agctcgttga gatcgcggcg aatagtctgc gggctaacgg agaaatgctc taccagctct
    53641 tcggtgctga cataaccctg ctgtttaacc agttcgataa taccgttgtg acgttgtgtt
    53701 tgtttcattg ataaatccct ggaattattt tcgttttcgc gcattgagcg aatcaacaaa
    53761 agccatcgct aaacccacgg ctaacccggc gatatgtgct ccgttcgcca tcgacatccc
    53821 aaacaaatca aaccatccgg cgacaatcca gatcaacgca aagataatta acccacgttg
    53881 caggtaaatg ccactttgcg gatcgcgttc gccacgtagc cagacgtagc ccatcagcgc
    53941 atacaccacg ccagaaagcc cgccaaacca cggcccgctg aatttttgct gcacatagcc
    54001 gcttaacagg gcgctaatga gagtaatgac aattagctta ccgctaccga ggcgtttttc
    54061 caccgcaccg ccgagatacc accaccagag caggttaaag aggatatgca tcagcgagaa
    54121 gtgcattaac gcgtgggtga agtaacgcca gaactcaaat ttcagcgtcg gatcgaatgg
    54181 ccaggccagc cataacatca cttcctgatc gccgagaatt tgcatggcga taaacaccac
    54241 cacgcaggcg atcatcatca cccaggttac cggacctgcg cgttcacgca aggcggcaaa
    54301 gaaaggataa cggcgataat gcaggccact gtcggtatga ccggactgcc aactggcggc
    54361 gagataacgt ggatctgccg ggttttcgag aaaacgagcc agctccgccc gcacgcgttc
    54421 ggcctgggac tcatccgcca gccagacatc gctttggtta tgttgttgaa tcgtgaggat
    54481 aacaccctgt gtcgccatgt aatcaacaaa cgcctgcgcc actcgggggt tagcaaaaga
    54541 ggtaatcatc aacatcgttg ctgtcgctta ttccacacaa aaggggacag tataaagcgt
    54601 tacgcgccgt acgccacctc tgcgggaaac tggcgctgcc aggcttcaaa accgccatca
    54661 atgctgtaga ccacatcgta gccctgttgc agcagatact gcgccgcgcc tttgctgcta
    54721 ttgccgtgat aacacatcac catcaccggt gtgtcaaagt cgttatcacg cataaacgcg
    54781 cccagtgtgt cgttagttaa atggaaagcc tgggtcgcat gccccattgc gaaactctgt
    54841 ggatcgcgaa tatcgaccag caccgcctct ttttcctgca acttctggtg cgcgtcggca
    54901 acgttaatac attcgaactg atccatgcgt ctctctttct ttacaaacaa gtgggcaaat
    54961 ttaccgcaca gtttacgtcg aagcggcaga taaacgccat aatgttatac atatcactct
    55021 aaaatgtttt ttcaatgtta cccaaagcgc gattctttgc taatatgttc gataacgaac
    55081 atttatgaac tttaacgaaa gtgaatgagg gcagcatgga aaccaaagat ctgattgtga
    55141 taggtggcgg catcaatggt gctggtatcg cggcagacgc cgctggacgc ggtttatccg
    55201 tgctgatgct ggaggcgcag gatctcgctt gcgcgacctc ttccgccagt tcaaaactca
    55261 ttcacggtgg cctgcgctac cttgagcact atgaattccg actggtcagc gaggcgctgg
    55321 ctgaacgtga agtgctactg aaaatggccc cgcatatcgc cttcccgatg cgttttcgcc
    55381 tgccgcatcg tccgcatcta cgcccggcgt ggatgattcg cattggtctg tttatgtacg
    55441 atcatctggg caagcgcacc agcctgccgg gatcaaccgg tttgcgtttt ggcgcaaact
    55501 cagtgttaaa accggaaatt aagcgcggat tcgaatattc tgactgttgg gtagacgacg
    55561 cccgtctggt actcgccaac gcccagatgg tggtacgtaa aggcggtgaa gtgcttactc
    55621 gtactcgtgc cacgtctgct cgccgcgaaa acggcctgtg gattgtggaa gcggaagata
    55681 tcgataccgg caaaaaatat acatggcagg cgcgcggcct ggttaatgct accggcccgt
    55741 gggtgaaaca atttttcgac gacgggatgc atctgccttc gccttatggc attcgcctga
    55801 tcaaaggcag ccatattgtg gtgccgcgtg tgcataccca gaagcaagcc tacattctgc
    55861 aaaacgaaga taaacgtatt gtcttcgtga tcccgtggat ggacgagttt tccatcatcg
    55921 gcaccaccga tgtggaatac aaaggcgatc caaaagcagt gaagattgaa gagagtgaaa
    55981 tcaattacct gttgaaagtg tataacacgc actttaaaaa gcagttaagc cgggacgata
    56041 tcgtctggac ctactccggc gtgcgtccgc tatgtgatga tgagtccgac tcgccgcagg
    56101 ccattacccg tgattacacc cttgatatcc atgatgaaaa cggcaaagcc ccgctgctgt
    56161 cggtattcgg cggtaagctg accacctacc gcaaactggc ggagcacgcg ctggaaaaac
    56221 tgacgccata ttatcagggc attggtccgg cgtggacgaa agagagcgtg ctgccgggtg
    56281 gtgccattga aggtgaccgt gacgattacg ccgcccgcct gcgccgccgt tacccgttcc
    56341 tgaccgaatc gctggcacgt cactacgcgc gcacttacgg cagcaacagc gaactgttgc
    56401 tcggcaatgc aggggcgata agcgacctcg gtgaagattt cggtcatgag ttctacgaag
    56461 cggagctgaa atatctggtc gaccacgaat gggtccgccg cgccgacgat gccctgtggc
    56521 gtcgcacgaa acaaggcatg tggctaaatg cggatcaaca atctcgtgtg agtcagtggc
    56581 tgatggaata tacgcagcag aggttgtcgc tggcgtcgta aggatgatgc ccggttgcga
    56641 agtgcaaccg ggctatttga attccttaga ctattcattg taaataattg aataacggcc
    56701 ccagagctaa aatcgccaaa cttaagcacg ttacccaatc gccccacttc ttcctatggc
    56761 ttctattttt gctacgccac tggcaataat atcccaacgc aaaaccaagc tgggcactaa
    56821 tcgggccgac aaaatcagtc cacggctgcg gccaaaaagg ggaaaaattc aggggaagcc
    56881 agacaaatgt cagaaagaaa tttcggatat tttccagcaa cgctgatttc tctggagaaa
    56941 tataaagaat gaaattcgag agaattaacc agaaatagac cggagaaaaa accagccagc
    57001 aatgtagcct gttttttaat tcaggaggcg ttctgcggga gaattgccaa ccgatgccac
    57061 ccattacact gaaaaaaagt gcatattcaa ccaataactc aagttgtaat tcctgaagag
    57121 aaatacgcac aaccaggagc ggaaaggaga atattatttc agccagaaaa gttaacgtga
    57181 atataagtac ggctaaggca ataaccgtcg gccataccaa taatggtacg ataacaaaac
    57241 cgaaaattac agggtaaata taaagtctga ttttattcat ctttaatgtc ctgatgattc
    57301 ggatgatgcg tcatacatgg cacataaaca ctcatcaatc atccactcgt cttcccaggc
    57361 ctgatactgt gtgccctgtt cggactgctt aagcggattc tcaatcgcct gccgcgcgcg
    57421 ttctttcagg atggattgat tattactagc ccaagtatta gtttgagtgg taatggcttt
    57481 atcgatatcg tcctgattat ctctgatata accgtcacga tacgtattca ataaacaggc
    57541 aagagacgct gccgaccaaa atccgggaac tgaaataatg gcatcaagca atggcgaaag
    57601 agcgatatcg gcacggaaaa acatttccag cttgtactgt aattcgacag cctcatcccc
    57661 ggatacccaa tcagtcatat actggcaagc aaattgctgc aatatttccc gttcatcctc
    57721 acgccagttt tctttactgg caaggttgat acgccgtaga gaaaatactt cgtgaatatt
    57781 gtcaaattgc ccctgcgcaa caaactccag taaacaaggc agaaaataac gaacctcatc
    57841 gctgttttgc ggatcaggtc ctggactact attccaggca ttgattaagg aataaggaat
    57901 cgctcgcaac gatgtattcc gtaatgcttt ttgttcctgt tgactcagac aatattcaca
    57961 acaaaccaca aattgctgcg gcgccggata acgacgaaaa atatgatata tctgctcaat
    58021 taatgcctgc atggcaggag tggggtgcat aattaccccc tcgcccgctg atcgtgcata
    58081 aacggctgat agataaaaag ggcattcgcc gcgttcagga aaatattaat gatatccata
    58141 ttgtaatcct gcttaatgca acgttttatc catcggcaca tagcccacat cttccaccaa
    58201 actctgcccc tgcggcgtta aaaaccactc caccaatttt tgtgtctctg acgtcgtatt
    58261 ttcccgcgtt accattaagg catcgacgat atagggatat ttgtcgttgc gaatattttc
    58321 cgcagtcggt gcaataccgt taatcgctag cagttttata tttttatcgg cattcatttg
    58381 tgttgcgtaa tagcggaagg tgtagcctat tgcgtttttt gtattacggt attcggcaac
    58441 aacgttaatc attccctcca tcacgcttgc cacttccgtt tcctgcggcg agatcatgcg
    58501 gacatttttc atgacctgcg atagcatcac cgtctggctg ccagagtctt ccgggcgttg
    58561 ccaggtctgg atctcctgat cgtcaccgcc aaccgcgcgc cagttggtaa ttgcgccact
    58621 gaaaatgtca cgcacctgtt gttcagtcag ggaattaacc ggattatccg cattgacgat
    58681 gaaaacaaac gcttcacggg caaatggcgt gtacagcaaa gtgacgcccg atttctcagc
    58741 gcgttttttt tgcccatcgg aaggttgcgc cacgaaaata atatcggcat caccgttaac
    58801 gattttgtta tatgcttctt gcgtacgaga gttatccaga taatcccaaa cgtgaaaatc
    58861 ctctggtatt acacttaatg cataaaatgc agaggcataa atggggtacg ccgccgtagc
    58921 gccatcgagt cgcggccagt tttgcgtaaa ttgaatttgt ggtttaccac gcagtggcgt
    58981 cagttgatta ttaagtttat cgggtcgcca ggcccaggta tcaatatttt cacgcacacc
    59041 gacaccggga ttaagctgtt tatataaata agcctgatac ccagcgacaa aaccaagtaa
    59101 gagaagtaga aacaggagta agttacggca acgtagcccg gacgtgccgg ttaaaggatg
    59161 ccttgtcggc cagccgtatc ccagcgaaaa actgatatgc gcgccaacgg gtataatgac
    59221 tatccaccag tagtcgccac tgattaatga gagtaacaaa acaccctgcc aggaaagcat
    59281 aaggtttgcc aaccagcccg atcccatctg gcgaaattga taatctgcca gatgtagcgc
    59341 gattatccag ccaaccaggg ttaatagcgc gggtaagaga aaaaagcatt gtcgccaggc
    59401 ggctatttct cttttttctg gtgcgctatc accagcccac acgcgaccag agaaaaatat
    59461 gattatcgcc cccagcgtca gcataaagac gttgagtaga agataaattg ttggcgtaaa
    59521 gagtaaattg caaacctcaa gaatagcggc aagcccggcc cccagcatgg caacaaccgc
    59581 tgccaaaaat tgcgccagta tggggatgcc aaaaaaagtc attaccagcg aggtcaaaat
    59641 ccattttccg ctttgcatta ttctttccat tcttgctgaa tggcgaaatt atactccccg
    59701 ataaccctcg ccccctctgg acacttttcc taaataaagg cgaaaaaaac gggacctttt
    59761 ggccccgttc tgttttttag cgaacttata atctcaccgg atcaatatgc caaatataat
    59821 cggcatactc tttgatcgta cggtcagaag agaagtaacc catattggca atgttcagca
    59881 tcgcttttgc ggtccactct tcctgacgct cgtagagttc gtcaacttta tcctgacaat
    59941 cgacatagct gcgataatcc gccagtacct ggtagtgatc gccgaagttg atcagcgaat
    60001 cgaccagatc gcgatagcga cccggatctt ccggactgaa tacaccgctg ccgatttgcg
    60061 tcagcacctg atgcagctcc tcatctttct cgtagtattc acgcggtttg tagccctgac
    60121 ggcgcaattc ttccacttct tccgctgtgt taccaaagat aaagatattg tcagcaccga
    60181 catgatccag catctcgaca ttcgcaccgt ccagcgtacc gatagtcagc gcgccgttaa
    60241 gcgcaaactt catgttactg gtgccggaag cttccgtccc cgccagcgaa atctgttcag
    60301 acagatcggc cgccggaatg atcaactgcg ccaggctaac actgtagttc gggatgaaca
    60361 cgactttcag cttgtcgcca atctgcggat cgttgttgat cactttcgct acgtcattga
    60421 tcaaatgaat aatgtgcttc gccatgtaat aggccgaagc cgccttaccg ccaaaaatat
    60481 tcacgcgcgg tacccacttc gcatccgggt cggccttgat gcggttatag cgggtgatca
    60541 cgtgcaacac attcatcaat tgacgtttgt attcgtgaat acgtttgatt tgcacatcga
    60601 acagcgcttt cggatttacc accacattca gctgctgggc gatatactcc gccagacgct
    60661 ttttgttctc cagcttcgcc tgatgcaccg cgtgattaac cattgggaaa tcacagtgtt
    60721 gttgcagatc attaagcagg ctaaggtcgg tgcgccagtt gcggcccagg tgttcgtcca
    60781 acacggctga aagcgatggg ttcgctaccg ccagccagcg acgcggcgtc acaccgttgg
    60841 tgacgttggt gaaacgaccc gggaagattt tcgcaaagtc ggcaaatagc gattgcacca
    60901 tcaggttaga gtgcagttcc gatacaccgt taactttgtg gctcaccaca accgccagcc
    60961 aggccatacg cacacgacga ccattggatt catcaatgat cgacgcccgt cccagcagat
    61021 cggtatcgtt cggatactgt tcctgcaagg ttttcaggaa atagtcgttg atttcaaaga
    61081 tgatctgcag gtgacgcggc agaattttac ccagcatatc gactggccag gtttccagcg
    61141 cctcgctcat tagcgtgtgg ttggtgtagg agaagacctg acaacacact tcaaacgcgt
    61201 cgtcccagct aaattggtgc tcatcgatca gcagacgcat catctcagga atcgacagca
    61261 ccggatgggt atcgttgagg tgaatcgcaa ttttatccgc caggttatcg taggttttat
    61321 gcaactgata atggcggctt aaaatgtcct gaatggtcga ggaaaccagg aagtattcct
    61381 gacgcagtcg cagctcacgc ccggagtagg tggagtcgtc cggatacagt acgcgagata
    61441 cgttctcgga gtggttttta tcttccactg ccgcgaagta gtcgccctgg ttgaatttac
    61501 cgaggttaat ttcactactg gcttgggcac tccacaaacg caacgtgttg gtcgcgtcgg
    61561 tgtcgtaacc tgggattatc tgatcgtaag ctactcccag aatctcttcg gtttcaatcc
    61621 agcgcgtttt tttaccttcc tgctgaatgc gaccaccaaa acggacttta tagcgcgtgt
    61681 tgtggcgttt gaattcccac gggttaccgt attccagcca gtagtcaggc gactctttct
    61741 ggctaccgtt aacgatgttc tgcttgaaca taccgtagtc atagcggatg ccgtaaccgc
    61801 gccccggcaa ccctaacgtc gccagagaat cgaggaagca agccgccaga cggcccaggc
    61861 caccgttacc gaggcccggg tcattttctt catcaatcag ctcttcgaga tttaatccca
    61921 tcgcttccag tgcgccctgt acatcttcgt aaattcctag cgacaacatg gcgttggaga
    61981 gcgtacggcc aatcaaaaac tccatcgaca ggtagtaaac ctgacgagtt tcttgcgaca
    62041 actgggcacg gtttgaacgt aaccagcgct ccacgagacg atcgcgcaca gcaaataacg
    62101 ttgcgttcag ccattcatgt ttattggcga cgaccggatc ctttccaatc gtaaacatca
    62161 gcttgtaagc gatagagtgc ttaagagctt ctacgctaag cgtgggcgat gaatatgtaa
    62221 acggagcatt catataggcg tttcctgaaa actatttcaa gcgatagtaa agctcacggt
    62281 acgacttcgc cgcgacctgc cagctaaaat ccattgccat agcctgacgt tgcacaaacc
    62341 gccacagtga aggacgggac cacagtacga aagcacgtcg aatagcccgt aacagcgacc
    62401 aggcattact atcttcaaag acaaacccac tggcgacgcc atctgcaagg ttctcaagag
    62461 aacagtcaga aaccgtatca gcaagcccac cggtgcgccg cactaacggc agcgtaccgt
    62521 acttcaatcc ataaagttgc gttaagccgc acggttcaaa acggctgggc accagaatga
    62581 cgtccgcgcc gcccataatg cgatgcgaaa atgcttcgtg atagccaatc tgaacgccca
    62641 cctggccggg gtattccgct gccgccgcaa ggaaaccttc ctgcagcacc ggatcgcccg
    62701 cgccgagtag cgccagctgc ccgccctgct ccagaagacc aggtaaggct tccagcacca
    62761 ggtcgagacc tttctggctg gtcagacggc tcaccactgc aaaaagcggc actttatcgt
    62821 caaccttaag ccccattgcg atttgtaact ggcgcttatt ttccgcttta tcttccaacg
    62881 tatcgcgggt gtaacgcgag gccaacagta agtccgtctc tggactccag attttctcgt
    62941 ccacgccgtt cagtacgccg gaaagacgcc cttcacggtg acgctgttgc aacagacctt
    63001 ccataccgta ggcaaactgc ggttcggtga tctcgcgagc gtaggttggg ctgactgccg
    63061 taatgtgatc ggcatagtac agaccggcct tcaggaaaga gatttgtccg ttgaattcca
    63121 gcccatgaat attaaagaat gaccatggca attggatgtc attcatgtga tgtgcataaa
    63181 acatgccttg ataggccagg ttgtgcacag taaacaccga cttcgccgga cgcccgcgcg
    63241 ccgccagata cgcaggcgca aggcctgcat gccagtcgtg cgcatgcacc acatcaggac
    63301 gccagaatgg gtcaagcccg ctggccattt ctgccccaac ccaccccagc agcgcaaaac
    63361 gcaatacgtt gtcggtatag gcaaataagt tggtatcgtg atacgggctt cccggacgat
    63421 catagagatg cggcgcgtca atcaggtata tgccaacccc gttgtaatga ccgaacaaca
    63481 gcgtgatatg tccggcgaag gtatcacgac gggatactac ctgcgcatcg gtcacgccac
    63541 ggcgaatatc gggaaatgca ggcaacagta cgcgagcgtc aacgccgtct gcgatttgtg
    63601 ctgcgggtaa tgccccaata acatcagcca gaccgccggt tttaagcagc gggaacatct
    63661 ctgaacatac atgtaaaacc tgcattatcg ctcctgttta tgccctaact tccgtagcat
    63721 ttcgcgcgtt accagcacga tgccttcttc tgaacgatag aaacgacgtg catcttcctc
    63781 tgcgttttca ccaatcacca tgccttccgg aataacacaa gcacgatcga tgacgcagcg
    63841 acgcagacgg cacgagcgac ctacccatac ttccggtaac aatacggcgg aatcaatgtt
    63901 gcagaatgaa ttcacgcgaa cgcgcgagaa cagaacggac tgcaccacca ccgaaccgga
    63961 gatcacacaa ccgccggata ccagtgagtt aagggtcatc ccgtggctac cggagcgatc
    64021 ctgcacgaat ttcgctggcg gtaatgattc attgtaggtg cgaattggcc aattgcgatc
    64081 gtacatatcc agttccggca ccacagaggc cagatcgagg ttcgctttcc agtaagcttc
    64141 cagcgtaccc acatcgcgcc agtacggctc ggcatccggg tcggattgta cgcaagagag
    64201 cgggaacggg tgcgcatagg ccagaccggc ttcggtgatc ttgggaatca aatctttgcc
    64261 aaagtcgtgg ctggagttct catcgcgatc gtcttcttcc agcagttcat acagatagtc
    64321 ggcgtcaaag acgtagatac ccatactcgc cagagatttg cctggatcgt tcggcattga
    64381 cggcgggtta gctggttttt caacgaattc gataatttta tcgttctcat caaccgccat
    64441 aacgccaaac gcggaggctt cttcaatcgg tactggcata caagcaacgg tgcaacgtgc
    64501 gcctttttcg acgtggtcga taagcatacg cgagtagtct tgcttgtaga tatggtcgcc
    64561 cgccaggatc accacgtatt ccgctttata acggcggata atgtcgaggt tttgggtgac
    64621 cgcatctgcg gtgccgcgat accagttttc ccctttcatt ctctgctgtg ctggcagcag
    64681 atcgacaaac tcgttcattt cttcattgaa gaatgaccag ccgcgctgga tgtgctgcac
    64741 cagagtgtgg gactggtact gggtgatcac gcccatacga cggatcccgg agttgatgca
    64801 gttagacagc gcaaagtcga taatgcggaa cttaccgccg aagtgtacgg ccggttttgc
    64861 tcgcttattg gttaaatcct tcaggcgggt accacgtcct cccgccagta tcagggcaac
    64921 agatttcaat ggcagctggc gtgccaacat taagtgatcg ttcttctcta aactaaccat
    64981 gactaactcc ttttttatca tctctggaac acacacaatc cgtgtgcagg tccctgccag
    65041 acagccgtaa tcactgggtt atcctctcca gcgaatgggg gaatggcgtg ccactcccca
    65101 gcaggtaaaa caatctctgt tacctcaagc gtggcgttaa ttgcgatcaa aaagcgatcc
    65161 gagagcagaa tttgcagctg tttcggcccg ttttgccact catccgtgct taaaggttga
    65221 gcatatcgat ttagccaacg gacattgccg tcgccttctt cccaccagcg attctccatc
    65281 aaagcgggaa tgcgcttgcg cagatggatt aacgcggcgg taaatgcggt taaaccactg
    65341 cttgcctgcg accagtccaa ccaggttaat tggttatcct gacagtaggc attgttattg
    65401 ccatgctggc tgtgaccatg ttcgtcaccg gccagtaaca tcggcgtacc ctgggagagc
    65461 aacaacgttg ttaacagggc gtgaatgctg tcgcgccgcc gttcaaccag atcaagagta
    65521 ccgcctaacc cttctttacc atgattgtta ctgtaattgt tgttggtccc gtcgcgattt
    65581 tcttctccgt ttgcttcatt gtgtttatgg ttgaagcaaa cgcagtcgcg aagcgtaaaa
    65641 ccgtcatgcg cggtgacgag attaatcgcg gcactcggca gacgatcatt acgtttaaaa
    65701 acatcgctgg aggcagcaaa acgcccggca aacgccccca gaggcaaatc ataatgcagc
    65761 cagaaacgac gggctgcatc gcggaaatga tcgttccact cggcaaacag cggcgggaaa
    65821 tttcccacct gataaccacc aggagcgata tcccacggtt cagcaattaa cttcacctgc
    65881 gagagcaccg ggcagttctg gatagcggta aacaacggcg catcctgacg aaactctggc
    65941 gtacggccca tgactgccgc cagatcaaag cggaaaccat cgacgtggca ggtttctacc
    66001 caataacgca ggcaggcgct ggcataatct accaccgccg gatgactcaa attgagcgtg
    66061 ttgccacaac cggtccagtt gtgataatcg ccgtcttctc ttatccaata atagctacgg
    66121 ttgtcgatcc cacgcagcga gaataacggg ccgtcgaggt ccagttccgc actatggttg
    66181 agcacgatat caagaatgac ttcgataccc gctttatgca gtgctttgat tgcatcgcga
    66241 aactcatcca gcgccgtttc tggcgagcag gcatacgccg gatgcagcgc aaacatcgcc
    66301 accgggttgt aaccccagta gttactaagc cccatacgtt gcagacgtgg ttcactggca
    66361 aattgtgcca ccggcagcag ttccagcgcg gtaatgccca actgtttcaa atagttgatc
    66421 atcaccggat gccccagggc tttataagtg ccacggatct cgaccgggat ctccgggtgc
    66481 aggtacgtta atcctttgac atgggcttca taaatgatgg tgctgcccca cggcgtgcgc
    66541 ggcggggcat catcttccca gtcatagtga tcaatcacca ctacgcattt cggcgcaatg
    66601 gcggcgttgt cgcgatagtc aggttcatta tgaccggcgt gcagcagcgg gttatcttta
    66661 aactccccgt caatttgccg cgcgcaagga tcaatcaaca acttcgccgg gttaaagcga
    66721 tgcccctcgg caggttgcca ggggccatga actcgataac cataacgcaa acccgggcgc
    66781 gcatccggca gataaccgtg ccaaatgtcg ccactgtgcc ctggcaagtc atagcgatgt
    66841 tcctggccat tggcatcaaa gacacacagc tctacccgct cggcatgagc ggagaaaagt
    66901 gtgaagttga cgccctgacc gtcgtaatgc gcgccgaggg gagtgggttt gccaatggcg
    66961 agttgtgtca ttctgcctcc cgaaccagcc agatagtggc cagaggtggt agcgtcaggc
    67021 tcagtgaatg ttgacgaccg tggctggcaa tctcatcgct gtgtactgcg ccgccattgc
    67081 ctgcattact gccgtgatag tgcatggaat cggtattgag gatttcacgc catttacccg
    67141 gctggttaat accgaagcga taatcatgac gcggcaccgg tgtaaagtta ctggcaacga
    67201 tgatttcgtt accctcttta tcgcgacgca caaagatcag caccgagcgt tctttgtcat
    67261 ccaccaccag ccattcaaag ccgtacgggt caaaatccag ttcatgcatt gctttatggt
    67321 ggcggtaggt gtggttcaga tcgcgcacca gacgctggac accgtggtgc cagttatcgc
    67381 cgccttccaa cagatgccag tcgaggctgg cgtcatggtt ccactcgcgg ccctgggcaa
    67441 attcgttccc catgaacagt agtttcttgc ccgggaatgc ccacatccag ccgtagtagg
    67501 cgcgcaggtt agcgaatttc tgccatgcgt cgcccggcat ccggtcgaga atcgattttt
    67561 taccgtggac cacttcatca tgcgacaacg gcaggacgaa gttttcagtg tagttgtaga
    67621 gcatcccgaa ggtcagttta tcgtgatgat actgacgata aatcgggtcg agcttcatgt
    67681 agtccagggt gtcatgcatc cagccgaggt tccacttgta ccagaagccc agaccgccca
    67741 tatcctgtgg acgagaaacg ccagggaaat cggtagactc ctccgccatt gtcactgcac
    67801 cggaaacctg ctcaccaaga atacggttgg tattacgcaa gaattcaatc gcttcaagat
    67861 tctcgcgacc gccaaattcg ttcgggatcc actccccctc tttacggctg tagtcgcgat
    67921 aaatcattga cgccaccgca tcgacgcgca gcgcatcaat accaaaacgt tcaatccagt
    67981 aaagcgcgtt accgacaagg aagttactga cttcacggcg accatagttg tagatcagcg
    68041 tgttccagtc ctgatgatag ccttcgcgcg gatcgctgtg ttcatacaag ttcgtgccat
    68101 caaattcggc aagcgcaaag tcatcggtcg ggaagtggcc tggcacccag tcgagaatca
    68161 cgttcagacc agctgcgtgt gcggcatcaa tgaaataacg gaagtcgtcg cgagtaccaa
    68221 aacggcgggt cggtgcatac aggccggttg gctgataacc ccaactgcca tcgaagggat
    68281 gctcgttaat gggcagtagc tcgagatggg taaagcccat ccatttagca taaggcacca
    68341 gttgatcggc cagctcgcgg tagctcaacc agaaattgtt gtcggtgtgg cgacgccagg
    68401 agcccaggtg aacttcataa atagagattg gcgcatcaaa ctgattcgct tttttgcgct
    68461 cttcagtctg cacaaccttt tccggcagcc cgcaaataag agacgcggtt tccgggcgca
    68521 tttgcgcttc gaaggcataa gggtcggact tcagacgcaa gttgccattg gcatcaatca
    68581 tctcgtattt atagagctga ccgttatgcg ccccagggat aaacagttcc cagattccgc
    68641 tctctttacg caggcgcatc ggatgacggc gaccgtccca gtagttgaat tgcccaacca
    68701 ccgagacccg acgggcgttt ggagcccaga cagaaaaacg cgtacctgtg acgccatcca
    68761 tagtatctgc atgcgcgcct aaggtttcat acgggcgtag gtgagtacct tcagataata
    68821 gccaggcatc catttcctgg attagcgggc caaaacggta aggatcatca atcaggtttt
    68881 gctgaccatg ccagacaaca gccaactgat agcggaaaaa attcttacgt cgcggaatga
    68941 caccgctaaa gaatccccgt gagtcgagac actccagttt tgcgagtttg cgcccggttt
    69001 tcggttcaat cacccacaca tcggtagcgt cgggtaaaag ggcacggact tccagtcccg
    69061 cggtggtttt atgcatcccc agtacggaaa aaggatccgc aaaatggcct gcaattagcg
    69121 cgttaatcac gtctctatcg atacgatcgg acatgcttgt cttcctgttt tattgtgtca
    69181 ccccatccaa ctgaattttt gacttctggt tgtgacattt ttttgacctg aacggcgcag
    69241 cactctgtgc atcctctctg cgtcgtcctc acttcaggta aggctgtgaa tactcgtgta
    69301 ttccgccacc cttaaagaat agccaatgct ctatttaact cccggtaaat catgaaacat
    69361 ctgcgcttac tcctgtatta cgcactagca ggggcggcat cgcgccccag atttaatgaa
    69421 taaagattac gccagttgac gaagcatccg acgcagcggc tccgcggccc cccacagcag
    69481 ctggtcgccc acggtaaagg ctgacaggaa ctctggtccc atattcagct tacgcagacg
    69541 gcctaccggc gtggtcagcg tgccggtaac ggcagctggg gttagctcac gcatagtgat
    69601 ttcccgatcg tttggaacaa ctttcgccca cggattgtgc gcagccagca gttcttccac
    69661 ggtcggaata gacacatctt ttttcaattt aatagtgaat gcctggctgt ggcagcgcaa
    69721 tgccccgaca cgcacacata aaccatctac cggaattacg gaagatgtgt tgaggatctt
    69781 gttggtttcc gcctgccctt tccactcttc gcggctctga ccgttatcaa gctgtttgtc
    69841 gatccacgga atcaggctac ccgccagcgg cacgccaaag ttatccaccg gcagctcacc
    69901 gctacgggtt aaggttgtga ctttgcgttc gatatcgaga atagcagagg acgggttcgc
    69961 gagttcatca gccacatggc catacagatg gcccatctgg gttaataact cacgcatatg
    70021 tcgcgcacca ccgccggaag cggcctggta ggttgcaacg gacacccaat caacaagatc
    70081 attggcgaat aaaccaccca gcgacatcaa catcaggctt acggtacagt taccgccaac
    70141 aaaagtcctg atgccattat ttaatccgtc ggtaatgacg tcctgattga cggggtcaag
    70201 aatgatgatg gcgtcatctt tcatgcgcag agatgatgct gcgtcaatcc agtaaccttg
    70261 ccatccgctt tcacgaagct ttggatagat ttcgttggta taatcgccgc cctgacaggt
    70321 cacaatgata tcgagggcct ttagcgcctc cagatcaaag gcatcctgaa gtgtgccagt
    70381 ggttccgcca aaagacggcg cagcctgacc aagctgagaa gtagaaaaga agacagggcg
    70441 aatggcgtcg aagtcgcgct cttcaaccat gcgttgcatg agaacggagc cgaccatacc
    70501 gcgccagccg ataaaaccaa catttttcat aagcgttttt tcctgcaaag atgtgtgctg
    70561 tataaatgtg ccggtctcct cctggcacat ctttcaccat acaaaaagca gccaaagtcg
    70621 caagtgaaat taatcaatga tagcgaagcc atcagtaatg cgacttatcc tgctttgtta
    70681 gcacgcagaa agtccgcggc aattatcagg gaatttgagt tatgaatgaa atcatttctg
    70741 caacagtttt attgatcctg attatggatc cgctcggaaa cctacctatt ttcatgtccg
    70801 tactgaaaca tactgaaccg aaaagacggc gggcaatcat ggtgcgagag ttgcttattg
    70861 ctctccttgt gatgctggtg ttcctgtttg cgggcgagaa aattctggca tttcttagcc
    70921 tgcgggcaga aaccgtctcc atttctggcg gcatcattct gtttctgatc gccattaaga
    70981 tgattttccc cagcgcttca ggaaatagca gcgggcttcc ggcaggtgaa gagccattta
    71041 tcgtgccgtt ggcaattccg ttagtcgccg ggccgactat tctcgccacg ctgatgttgt
    71101 tgtctcacca gtacccgaat cagatgggac atctggtgat tgctctgctg ctggcctggg
    71161 gcggcacctt tgtcatcctg ctacagtctt cgctattttt acgtctgctg ggcgagaaag
    71221 gggtgaacgc acttgaacgc ctgatgggat tgattctggt gatgatggca actcagatgt
    71281 tcctcgacgg cattcgaatg tggatgaagg ggtaaggttc aaacaggtgt tgcacacaac
    71341 cagacgcggc acctgtttta ttacctgaac tgataatgac cttcgcccaa tcggataacc
    71401 cttccctctt cttctgcgcg gttcagccac acactaattt gttcgatggt taaaccagta
    71461 caagacgcca gcctttcaat acttatcgat tcctttgcaa ggatcgccag ttccgccaca
    71521 aagagttgat aaaaatcgac aggggtatgc gcgggcatta ctgcgtaatt tgcgtcatct
    71581 tcgtgcagcg aaaacagttc tggttgagcg ttacggagtg ctctgtcata catcagccca
    71641 ggaacgtctg gcagtctgat cgtcacattc tcagcctgtt cagcactcca tgacgcccca
    71701 ttttctacta atcgtgaatt ggctgattgc atatcctgat ttggtttaac ctgcatgggc
    71761 agccactgat gttttaatgc ctccatcgcc ccggttatcg ttccaccggt cattcccgca
    71821 cgtacaacca ttgcgctttc agcaaggcaa taaatatatt tattccgcgc catcgcattg
    71881 ccgacggtga aacgtacctc tgggtaaaac ggcgaaatca acaccaggtt gcctgctata
    71941 agcccttcac gccatttcac taacgtactc gtttttaaca agctatcagc taatacgcca
    72001 acggcagttc ccccgacctc cagagccgag gccattgcac attcatcaat acctcgcgca
    72061 ccaccagaga taacgcaaat cccctgttgg gccagtttcg cggccagttg ttgggtatag
    72121 cgcaaatcgt cagtcggagc atctcgcgag ccaacaatcg ccataccttc cgcttgcagt
    72181 aatgctttat tcccgcagcc aaataaaacg ggaggtgcat ccgttcgcaa tcggtttttc
    72241 aagcgaacgg gataatcggc atctccgcgg gttaagatcc ataaaccggc gcgttgccac
    72301 ttatctacag ccaacgccag actatgacca cgcgccagca agccaagaat tcgctcctga
    72361 gaaatacgcg gatcgctcca gcctgtaagt ttctcttgcg gttgcggcac cagaagctcg
    72421 gcgggactga tacgttggtg cttcagccat aatgcaaact tcccccattc actattacta
    72481 agaggtttat actcactcgc cgccgcgcga gaaaaatcgc tggttagcag gagagttgct
    72541 tgagcattgg ctgaaagatt catcaatttt ttaccgaggt agaagcaagg gcaagaggat
    72601 aaaccgtcgg gcaacctgcc tggcgtaaca gtgctgtcag aactgtcagc gtccatgcag
    72661 aatccacgat atcatcaacc agcaacgccg gacctggcat caaaggaggg gtaatcacaa
    72721 acgccccgtc gagattttga cactggtgaa aacggttttg ctgcattttc tgcggtggat
    72781 tgtccacgac tttttcaatg gcatcaataa aaggtaagcc aagtttcgcc gccagtcgcc
    72841 gggcaaaatc aggaaccagg tcgaggtgcc ttaatgaagg aacgcagcat acccaggtgg
    72901 gttcaggatg cggattccag cgttggcgaa ccatttccgc acatgcctcc accagctcat
    72961 cactgaagcg ccccgttttt ttctcctggg ctacctgctt tccccacccg gaatctcccc
    73021 aacgagaaag gattcgcccc gtagatcctt gtaaacccgc aggcaagttc cctttaaatc
    73081 cgtattgcgt aaaagcccca gatgccacct gtttattgag atttaatggc aggtcagcgt
    73141 gtttaataaa taaatttgcc gcatggagta agtcgctatc aatgtcgggc gacaacagcg
    73201 gatgctgaag acaactgcta catttaccac aacgttcggc acttggctca tcgagtgcgc
    73261 ggcgcagaaa ttgcattttg cactccttgg tcgtgatata gctttcaacg tctgccaact
    73321 cactttttct ctgattcatc aaatggttaa ttcgttcatg atcaggagaa aaactgacga
    73381 tagttctgcg ccataatttc tcggtataca ccacaggcga tggattttca gctaccaata
    73441 atttcagtgc tttttctatt tgcccataac gaagattcgt ccgttgttca atgcctcgta
    73501 gggtaagacc gtcattctcg ctaagtacgt tgagtatttc atgaatttgc gcctccgcag
    73561 gaaaggcgct ttcacggaag aattgatgaa tagcgcggtc ttcaccacca caaagcaata
    73621 tgccaactgc ggaatctata gcacgcccgg cacgccccac ctgttggtag taaccgacaa
    73681 tagaccccgg catctgataa tgaatgacga aacctaaatc aggtttatca aatcccatac
    73741 ctaatgccgt cgtcgcgacc agcactttga ttttatttgc cagcagtgcc tgctccagat
    73801 actccctggc agtattagaa tcttccgcac cttcacaagt cacgccgctg taataagcaa
    73861 atgcactgat accatttttc cttaaccact cggcgacaag ttcagcatcg cgagtcgtca
    73921 gggtataaac aattcccgat ttggaaaact gagggataac cgttgctaac catgccagac
    73981 gggatgactg ttctcctaag actaaggcat caagcgccaa actttcgcga gccagcgttc
    74041 cacgctgaat cacaatgtca cccaattgct gacggatatc ctcaacgaca cggttattcg
    74101 ctgtcgcggt tgtacccaga ataggggtat tcgcaggcag ttggcgcaaa atatctaata
    74161 tacgtcggta atccgggcgg aaatcgtggc cccaatcaga gatgcagtgc gcctcatcga
    74221 ccaccagtaa accgatgcgg tcagcgactg gatataaaac cgtttcaaga aaatcctgat
    74281 tcgccaaccg ttcaggtgaa atcagcagac aatctacgcc accttgcagc aacttatcgc
    74341 taatgcgctg ccattcttcc ctgtttgtag aattcaacgt ttcagccgta atacctaacc
    74401 gttcagcggc ggcaacctgg ttacgcatca gggcaagcaa aggagagatg ataattgtcg
    74461 ggccagcgcc gcgatcgcgg aagattttac tggcgatgaa gtacacggca cttttccccc
    74521 agccggtgcg ctgtacaacc agtagttttc gccgctgatt aaccaccgca tctatagctt
    74581 cccattgccc ttccctgaaa gtagcgctgg tgttacttaa catccgctgt aacagcaatt
    74641 cagctccgtg tttctccatc atcttctccc tcgtccgtta acacagtgat tagaacggat
    74701 aatgttccgg tctttttgcg agagagatca aaaagatgaa gacaggagaa aagagaaatg
    74761 aattactgcg agcaagctcg cagtaatttg tcgcagtaat taactcaaca gctggaacgc
    74821 aatcatccca acgatggcac cgacagtgcc gaggatggtt tccatcatgg tccaggtttt
    74881 aagcgtttcg gcttcggtcg cgccggtaaa tttaccgaac aaccagaaac ccgcgtcgtt
    74941 aacgtggctg acaacaatcg aaccaccggc gatacaaatc gacagtgccg ccatttgcgc
    75001 accggagtag ttcagttgtt caatgaccgg cattaccaat cccaccgccg ttaaacaggc
    75061 aacggtagca gaaccctgaa tgatgcgcac tgcagctgcc agcacgaagc aggtgatggc
    75121 aatcggcagg cccatgccgg ttaacgcttc gcccagtgcc ggaccgacac cagagtcaac
    75181 cagcacctgt ttgaacacgc cgcccgcacc aatcaccagc agaatgatcc ccgccggttg
    75241 cagcgcgtga ccgcaaatct ccatcacttt gtcttttggc ataccctgac gcattgccag
    75301 accgtaaatc gccaccaggc aagcaaccag aatcgcggta aacggatgac caataaactc
    75361 gaaccattcg taagcggtag aaccttctgg cacaaaacgc gcggcaatgg ttttcagccc
    75421 caccagcacc agtggcaaca ggatcagcga caggctgaat ccgaaggacg gcattttgcc
    75481 ttcgccgaga tgcggttcgc tgatgtcgtc aggaatatgc aactccacgt agcggctgat
    75541 gaaattaccc cacagcggcc cggcaataat cattcccgga attgccgcgc acaggccaat
    75601 caggatcatc cagccaaagt cggcgttcat ctgcgatgcc agcagcattg gcgctggccc
    75661 aggcaccagg aacgcagccg ctgccgccac gccggcgaat aatgggatta ccagcttcac
    75721 caggttcgtg ccggtgtggc gcgccattga gaaagcaacg ctaatcagca gaacaatcgc
    75781 cacttcaaag aacagcggta gcgcacaaac cagccccgca aggccgatgg cataatgcac
    75841 gcggctgtga ccgaaggatt tgagcatttt gacggcaatc tgatcgaccg cgccggtttc
    75901 atgtaagatc ttaccaaaca tggctcccag ggcgacaacc accgccagga agccgagggt
    75961 gcctcccatc cctttttcca tcgtcgctgc gattttatcg agcggcatac cggaaaaaag
    76021 gccagccccc atggacacca ccattaaagc caggaaagcg tgcatacgcg ccttcatgac
    76081 taaaaacagc agcagtaaaa cagaccctac tgctgttaaa acaagcgtta atgtagtcac
    76141 tacttatttg ccttttttaa taacctcaat ggtgcttgcc acaacacctt ccagcggttg
    76201 atcaatatcc accaccagta catcggtttc gtccgcaccc ggctcctgca gcgtttcaaa
    76261 ctgcgtcacc aacatttggg ttttaaagaa atggcctttg cgcgctttca ggcggctttc
    76321 aatcacatca aaatcgcctt tcaggtagat gaaagagaga ttaggattac cttcacgcag
    76381 caagtcgcga tagtgttttt tcagtgcaga acagacgatc agcgatactt tattggtgcg
    76441 ctgcatagca aacgcggcgt cgttcagcgc ctgcaaccac ggtttgcgat cgtcgtcatt
    76501 cagcggttcg ccagacgcca ttttttcgat attgcagcgc ggatggagga aatcgccatc
    76561 aagaaacgcg gcatgaagtt gatgcgccac ttcactggcg accgcagatt tgccgctgcc
    76621 cgatacgccc atcaagacgt aaatgtggtg atcatggtta gtcgtgctca aagtggtgcc
    76681 cccacaatac aagaattaaa aatgttacgg gtaactgtta tcggtaacat tgtccagccg
    76741 gacaatatca gaagcaatat ccatccgtgc cttaagtgta taagtgtgag ctacttcaaa
    76801 tttgtaggct taaatagatc cgcccggtga caaggtgaaa cctaaatcta acattttcgg
    76861 tgtcacagat tcgccacgaa tacgcgccag caggcgctca gcgccaatgc tgcccatccg
    76921 ctcacgcggc gtcagcacac tcgccagccg tggctccatc acctgaccaa tgtcatgacc
    76981 gtggaaaccg gcaatcgcca tatcgtcagg aactttcaac cccagacgct gacattcaaa
    77041 cgccgcgccg accgccaggt catcattagt acagaacacg ccatccagct gcggatattc
    77101 ccgccgcgcc tggcgaatca gttcaatacc ggaagagtaa gaagaagatt gctcaaccat
    77161 cacgctatac ggcaccaggc ctgcatccag catcgcctgt tcgtatccct tctgtttgat
    77221 gatagtacgt tcgtcgagac gtgcgccgag ataggcaatg tggcgatgcc cgcgagcaat
    77281 aatggcggtg gtcatctggc gtgccgcttc aaagttatca aaaccgacgg cgatatcgag
    77341 acacggcgac ttactgtcca tcaactccac caccggaatc cccgccactt caatcatctt
    77401 taaggtgcgt ggcgtgtggg tacgttcagt gaggatcagg ccgtcgatat tccatgagag
    77461 cattgattcg aggcgttctt gctccatttc cggtttataa ccgtagtgcg ccagcatggt
    77521 ttgataaccg tgcgcgtcgg tgacactttc gattccgcgt aatacttccg cgaaaacctg
    77581 gttggtgaga gaaggtaaca ggacgccaat cgcccggctg gtggcgttag agagtatatc
    77641 gggcgcgcga ttgggaatat aacccagttc atcaagagcg gcggcaatct tgccgcgtag
    77701 agcgacggaa acctgctccg ggttgcgtaa aaaacggctg accgtcattt tggtcacgcc
    77761 tacacggtca gccacatcct gaagtacggg tcttttcttt ttcatcgtcc tgaaggtaca
    77821 aaagagatag attctcttag tttaacacgg acgcatcaca accttcctga ttcctcagga
    77881 aggtttgtga gataaattta gactggcggt aaatcgaaca gcaggatttc actgtcgcta
    77941 tcagcatgga tggaaatcgc ctgctcatcc cagattgcca gaccatcgct ggtcgaagct
    78001 tttacgccgt taatggtgac attgcctttc accacctgga tccagatgcg gcgttcagcg
    78061 gcaatctgat gcaccgactg ctcatctttc accagcgccc aacgatacag ttccatatcc
    78121 tgatgcactt tcaatgaacc atctcgcgca tccggcgaaa gcaccagttg tttgccctgc
    78181 acggcatcga agcgacgctg ttcataacgc ggcgtaatac cgttttcttc aggcatgatc
    78241 cagatctgat acagatgcag acgctcggtg ctgcttgggt tgtactctga gtgacgaata
    78301 cccgtacccg cactcataat ctggaactcg cccgccggaa cctgctcttt attgcccatg
    78361 ctgtcctggt gctcaacagt accttccagc acgtaggtca aaatttccat atctttatgc
    78421 gggtgagtgc cgaagccctg ccctgcttca ataacgtcgt cgttaatcac gcgcagcgca
    78481 gagaagccca taaagttcgg atcgtaatag ttggcaaaag agaaagtatg ccaggagtcc
    78541 agccagccat gatttgcatg accgcgttca tttgctttgc gtaagtagat catttgtatt
    78601 cgccccctga atgatttcga tgggcttagt gtggacccga tccgcctggg atgatagagg
    78661 gtgaaaattg acccctctgt tcaaaaaaat tgaactattc gaggggccat caaacttacc
    78721 tcgcgagact cactgcggag ggagaagctt gctcaaaacc gcgttcaagg atttccagat
    78781 tcgtaagaac ttcagattcc ttgacgtaat ttggcgcacc gttggtaatg gtttgataca
    78841 acgcatcata aacgcgccca taatcgccca tctctggctt catctcttct cttaccgtca
    78901 cgccctcgtc attgacatac tccagcacac cgaccgaatc atccgctgcg aatcctggtt
    78961 cgcccggcat aatattagcc ttcaggctgg tttcctgctg gtcgataccg tatttaataa
    79021 acgaaccttt cttaccgtga acgataaatt tcggataatc gattttcacc agatggctgg
    79081 ttttgacgat ggcttttaga tcgccataaa acagctgcgc ttcaaaggtg tcgtccggat
    79141 tggctttatt acgcaggctg cggatgtcat aagcgacgtg atccgggcga ccgaacagag
    79201 aaataatctg gtccatcgta tgcacaccaa ggccatagaa cgcgccatcc tgcggcagcc
    79261 ccggtttggt ttctgccacc gggcggtaat agtcaaaatg gctttccact tcgacaatct
    79321 ctcccagctt gccgctttca atcgcttttt tcgctgtcag gaagcaggaa tcaaagcgac
    79381 gattctgata cggcgtaacg atcagccctt tgcttttcgc cagtgcaaac agctctttcg
    79441 cctgcgcaat tgtcggagtg aacggttttt cgaccagcac atttttcccg gcttccagcg
    79501 cgcgcttcgc gtactcgaag tggctgtccg cgtgggtgca gacgacaacc agcttaacat
    79561 cgggatcgtt tagcacttcg tcgagatcgc tggtgaaatg gatatgggaa taaatggggg
    79621 cctgttcttc cggcttcgca tggcggcgaa aaatatgcgc gacatgccag ctatccttgc
    79681 ggttaagtac atacggcaga tggtaacggg tggtgctttt gccgaagcca ataaaggcgc
    79741 agttaatgac catgatttcg tcctttttaa ggtggttatt tacaccttag cgcaaagcgg
    79801 acgtggttcc tactggagtg cgcataacga acacaagcac ttcccgagga taaattgaga
    79861 acgaaagatc aaaaaaaaag ccagcacccg gctggctaag taatactgga agcaatgtga
    79921 gcaatgtcgt gctttcaggt tctccgcgag ggtcttcctg atcgcgagac aataataatc
    79981 attctcattc gcacttgtcc aacacttttt gcaaaaaaat gcatttgact cgcatttgaa
    80041 agtcaatgat gttgaaaggg acatttaccc caaagaggac aaaggaatga gtgagatagt
    80101 aatacgccac gcagaaacac gcgattacga ggccatcagg cagattcacg cccagccgga
    80161 ggtgtattac aacacgctac aggtgcctca tccttcagaa caaatgtggc tggaacgact
    80221 caccgctcgc cctggcatca agcagttagt cgcctgtatt gatggaatcg tcgtaggcca
    80281 tctcaccatt gacgtgcaac aacgcccacg ccgcagtcat gttgccgatt ttggtatctg
    80341 tgtcgactcc cgttggaaga accgcggcgt cgccagcgcc ctgatgcgag agatgattga
    80401 aatgtgcgac aactggttgc gggtagatcg tatcgagcta acggtgttcg tcgataacgc
    80461 gccagcaatt aaggtctata aaaaatttgg ctttgagatt gaagggactg gcaagaagta
    80521 cgcattacga aacggtgaat atgtcgatgc gtattatatg gcgcgtgtga aatagagaat
    80581 ttgcaatcta cgtttgtcat ttaagccctc acctaccggg agagggctta agatattaat
    80641 accccgccgt taaatcatcc accgagcgcg ggtcggatgc accgtacagc tcaccgtccg
    80701 gcccaaccat aatgctttgt gtactgccca tcgcctcttt cagcgccact ttctgacctt
    80761 ttgcttccag cagcttgatc gtatccgggc taaacccttt ttcgacacgc agctcgtccg
    80821 gcaaccactg atggtggaaa cgcggcgcat tggtcgcttc ggcgacgttc attccataat
    80881 cgatgctatt caccaccatt tgcagcacag tggtgataat ccggctaccg cctgggcttc
    80941 cggtgaccag ccaggtttta ccatccttga ccacaatggt tggtgacatc gacgacagcg
    81001 ggcgtttatt cggcccgacg gcgttggcat cgccgcccac cagcccgtaa acgttcggta
    81061 cgcttggttt ggcggagaaa tcatccatct ggttattgag caaaataccg ctctcgcccg
    81121 cgacaatgcc cgtaccgaag gtggtgttca gtgtataggt caccgccacg gcgttaccgt
    81181 ctttatccac tactgagtaa tgggtagttt gattactctc ataaggcgca agcttgccag
    81241 gacgaatttc gctggatggc ttcgctttat tgatatcgat ttgatcggca atagatttgg
    81301 cataggcttt attggtcagc gcctgccacg gtactttgac aaaatccggg tcgccaagat
    81361 attccgagcg gtcggcgtag gcgtatttct cagcttctgc catgatttgc atcgcgtcgg
    81421 cgctgccaaa gccgtacttc tgcatatcga agttttccag aatattgagg atttgtacga
    81481 tatgaatacc gccggaagat ggcggtggca tggagtaaac ctgatacccg cgataatcgc
    81541 cgcttatcgg tgtgcgttcg accgctttat atgccgctaa atcttctttg ctgatcaagc
    81601 caccgttttt ctgcatctcc tgggcaatct gttccgctat cgtgcctttg tagaattcat
    81661 ccgggccgtt ttcggcaatc atctccaggc tctttgccag gttcgcctgc accagcttgt
    81721 cgcccttttt cagcggttcg ccctctttcc agaagatagc tttgctgttt tcgtggttcg
    81781 gcagcacttc actgccgtag gttttgagat cgtcagccag cgcgtcgtta acgataaaac
    81841 catcgcgtgc cagtttaaac gccggttgca ccactttatt caacggcatg gtgccgtatt
    81901 tatccagcgc caacgagaaa cccgctaccg taccgggtgt gccggaagcc agatgcgaag
    81961 tgagtgattt tttgctgtcc gtgttgccct gatcatcgag gaacatatcg cgggtcgctt
    82021 tggcgggtgc catttcgcgg aaatcgatag ccgtggtatt gccatttttc gagcggatca
    82081 gcataaaacc accgccgccc agattccctg cctgaggatg cgttaccgcc agcgcgtagc
    82141 ccaccgccac ggcagcatca acggcattcc cgccctcctt gaggatatcc actcccacct
    82201 gagtggcagt aacatctaca gacgccacca tcccttgttt cgcgcgtacc ggatggaaga
    82261 catcttcctc cacaccataa gaaacaggag gcgcggctac cgtactaaaa caacttcctg
    82321 tgagcagagc agcaatggcc acccggcgta aaaacgtcgg ttttatcatc gttattctcc
    82381 agagattaag gggcaacccc agctaagcct ggtatataac tctgaattaa tcatcgtttt
    82441 gccgggaagc gagtaaactt aaagaatatc ttcagaggag gatacgcgat gaaacgactt
    82501 ctgcttttga cggcactcct gccgtttgtc ggctttgcac agcccattaa tactctgaac
    82561 aaccctaacc agccgggata tcagatcccc agccagcagc ggatgcaaac tcaaatgcag
    82621 acgcagcaaa ttcagcaaaa agggatgctg aaccagcaac tgaaaacgca aacgcagctg
    82681 caacaacagc atttagaaaa ccagataaac aataattctc agcgggtgtt gcagtcacaa
    82741 ccgggggagc gaaatcccgc ccggcagcaa atgctgccca acaccaacgg cgggatgtta
    82801 aacagcaacc gtaatccgga tagttcgttg aatcagcagc atatgctgcc ggagaggaga
    82861 aacggcgaca tgctgaatca gcccagcacg ccgcagcctg acattccgtt gaaaactatt
    82921 gggccgtaaa gttcggacca atcacgtcaa tcgcatcggt acagatgcaa tccacgcccc
    82981 agcgcagcaa ctctgccgcg cgctggggtt tattgacggt ataaaccaga attcgcagtc
    83041 ctgcatcttt caactgcatc actcgcgctt tatcgagcaa cttataattg agatgaatag
    83101 agacgcagcc cagccgcgcg gtcaattctc gccagtcgtc gcgccattca tcaagcaata
    83161 aaccacgcgg cagttccggt gctgcctgtt gagcggcttc taaagcatca atctcaaacg
    83221 atgacagcag cggcggcgtc ataccggtcc acagttcgcg tgccgccaac gccaccattt
    83281 tgcccgttaa tggtccagtg tcagtggtgg gtttgatttc gatattcgcc atcatcccgt
    83341 gtttgcgaca gcgttccgcc acctgcgaaa gcaacggcag tggctcacct ttaaacgctt
    83401 tgctgtacca actgcctgca tccacgcgca gtaaatcctg ccagttcagt tcacccgcga
    83461 cgccccagcc gttgctggtg cgttcaagat tgtcgtcatg gagcaggaag atctcgccat
    83521 ctttcgataa cttcgcgtca aattcgatca tcttatgacc gtattttgcc ccgacgtcga
    83581 ttgctgccag ggtgttctcc ggggccagtt taccgccgcc acgatgggcg acgatgcggg
    83641 gataaggcca gttactcata ctcgttgtcc tgtttcacca tcaaaaagat gtagctgatt
    83701 ttccggcaga tgcagccaca gcgtgctgcc tgccgtcggg cgctcctgat gtgccagtcg
    83761 caccaccagc ttctgttcgc cccaatgtcc gtgcgccagg ttatctgcgc cgaggatctc
    83821 cagcgtgtcc atcaccagcg gcacaccacc ttctgcctgc gagcttagcg ctatatgttc
    83881 cgggcgaatg ccgagggtca ttttacgccc gacatactga cggtagccac cgtttagcgg
    83941 cagcgcaata ccgccatcca gttcgaaatg cgtaccttcg ttattcacac ggccagccag
    84001 taggttcatc gccgggctgc cgataaaact cgccacaaac aggctggcgg gcttttcgta
    84061 cacttcaact ggcgtgccaa tctgttcggc aacgccgccg ttcatcacca ttactcgctg
    84121 ggcgagcgtc atcgcctcaa cctgatcgtg ggtaacgtag agtgaagtcg ttttcaggcg
    84181 acggtgcagc tgttgcagtt caagacgcat ctgcacacgc aacttggcat cgaggttaga
    84241 gagcggctca tcaaatagga acactgccgg ctcacgcaca atcgcacgcc ccatcgccac
    84301 acgctgacgc tgaccgccag atagctcacg cgggcggcgc ttaagcaggc cgtccagctc
    84361 cagaatgcgc gccgcttctt taacacgttc ggcaatttgt tgcttgccca tgccgcgaat
    84421 tttcagcccc cacgccatgt tctcctctac gctcatatgc ggatagagcg cgtagttctg
    84481 gaacaccatc gcaatcccgc gatctttcgg ctccatttcg gtgacacgct tgcggtcgat
    84541 ccagatatcg cccgtcgtta cccgctccag tccggccacc attcgcaata acgtcgattt
    84601 cccgcagcca gacggcccga ccatcacgat aaattcgcca tccgccacat caagggtcag
    84661 cggtttaatg acctgggttt tgccatccca gcttttggtt actgcctgta atttcagtcc
    84721 tgccatctta tttctcacta tcgaccaggc cgcgcacgaa ggcacgctgc atcactaaaa
    84781 caatcactac tggtgggatc agggttaaca acatcgccgc catcaccgag ttccattccg
    84841 ttgtgccttc gcctgtggcg atcatccctt taatccctgc cacggtggtg ccgagatcaa
    84901 cgtcggtaat aatcaacaac ggccacaaat actggttcca gccgtaaata aaggtgatca
    84961 caaacagcgc cgccagattg gttttggaca gcggaaaaac gatgtcgcaa aagaaacgca
    85021 ttggcgacgc gccgtcgatc cgcgcggctt ccaccagttc atccggtagg gtcataaaga
    85081 actggcgaaa cagaaacgtg gcggtcgccg aggccatcag cggcagcgtt aaacctgcgt
    85141 agctgtcgag cattttcagg ttggcgatga cttccaccgt cgggaagata cgcacttcaa
    85201 ccggcagcat cagggtgata aaaatcatcc agaagaagag gttacgtagc ggaaaacgaa
    85261 accagacaat ggcaaatgcc gagagcatcg agacggtaat tttgccgagc gtaatgctga
    85321 acgccatcac aaagctgtta agcaacatcc gccagaacgg cgcgctattc gtgcctaccc
    85381 cgtttaccca gatgttgtgg atgttttcca gcagatgtgt gccgggaata agcgtcatcg
    85441 gcgcggcgta gacttcttgt ttatccagcg tcgccgcgac aaacgccacg tacagcggga
    85501 agaggatcac cgcgatcccg aggatcagca tggtatggct gaatattgtc agccacggac
    85561 ggttctcaat cattggtaac gtaccttgct ttcaacatag cggaactgca ccaccgtcag
    85621 cacgatgacg aggaacatca acaccaccga ctgcgcggca gacgaagcca aatccagtcc
    85681 ggtaaagcct tcacggtaga tcttataaat cagcgtcgtg gtggcctgta ctggcccgcc
    85741 ggacgtggcg gcgtcgatca ccgggaaggt gtcgaagaag gcatacacca ggttcaccac
    85801 cagcaggaag aaactcaccg gagcgataag cggcagcgca atcttaaaga agcggcgaat
    85861 cgggccagcc ccatcaatgg ctgcggcttc gatcaacgaa cgggggatgg attgcagcgc
    85921 ggcatagaag aacagaaagt tgtagctgat ttgcttccac actgaggcaa acaccaccag
    85981 gaacatcgcc tgaccgctgt tttgcgcgtg gttccagtcg tagccgaact cagcgagaaa
    86041 atgggtgatc agcccgcgac cggggttaaa cagaaagatc cacaatacgg cggcaacggc
    86101 gggagccacg gcatacggta gcaacatcaa ggtttgatag aaacgactgc cgcgcacgat
    86161 gtactccacc agcgctgcga agaacagcga taccagcaaa ccgctgacgg tgacaaaggt
    86221 gctgaatttt atcgtcgtcc agaaggcgtc gagatagtag ctgtcgtgaa acagcgtgac
    86281 gaaattatcc aggccgacaa actggctgga gaaaccaaac ggatcgacgc tttgtagcga
    86341 gtaccacaac gcttcgcccg caggccagat aaaaaagata acggtgatga tgagctgcgg
    86401 cgcgaccagc aaataaggta gccagcgcga gcggaacacc ggacgggatg atggcattac
    86461 tgttaattcc tgaactgtgc cggatgcgct tcgcttatcc ggcctacacg cgatgccagg
    86521 tcagataagc gaaacgcatc cgacattaca ctgattaaga cttcgtcgat ttctcaaagc
    86581 ggcgcagtaa ctggttccca cgctcaacgg cagtatccag cgcctgctgt ggtgtcttct
    86641 taccggtcca cacgctctcc agctcttcat ccacaatcac gcggatctgc ggcatgttgc
    86701 ccagacgcaa acctttggtg aacggcaacg gtggcttgtt cagcatctga cgcgtggcaa
    86761 tatccgctcc tgggtttttc tcgtaaaagc cctgctcacg ggtcaggtca tacgccgctt
    86821 tagtgattgg tagataaccg gttttctgat gccactcggc agcgttttct ggttttgcga
    86881 ggaagtcgag gaacttcgcc acgccggtgt aagtttcttt atctttaccc tgcatcaccc
    86941 acaggctggc cccgccgata atggcgtttt gcggcgcgtc tttcgcatcg gcgtcgtaag
    87001 gcatcatgcc tacgccatag ttaaatttgg cgtactcgcg aatgttggca agagaaccgg
    87061 aagaggcggt cgtcatcgcg caatcaccgt tatagaactt ctcggtggat tcatccttac
    87121 gcccaacgta gctgaaatcg cccttcttgt tcatctcttc gagcatggcg atgtgtttca
    87181 cctgctccgg cttgttgaac tcaagcaccg cgtctgtgcc gtcaaagccg ttgtttttgc
    87241 tggcaaacgg cagaccgttc caggcgctaa agttttccag ttggatccag ccctgccagc
    87301 cgctggcgta gccgcacttc atgccggagg cttttagttt tgcggcatag tccgccagat
    87361 cctgccaggt ttttggcggc tgttccgggt ctaatcctgc tttcttgaag gcgtctttgt
    87421 tgtaatagag aacgggggtc gaactgttga acggctggga aagtaagtgc ccagttttgc
    87481 tgtcggagta gtaaccggaa accgtcggca caaactgcga ctcatcgaat tgaatccttg
    87541 cctctttaaa tacgtcatac accggtttaa tggctttcga cgccatcatg gtggcggtgc
    87601 caacttcata aacctgcaaa atagccggag cgttgccggt acgaaatgcg gcaatccccg
    87661 cgcttaaatt ctgttcgtaa ttgcctttat aggtcggtac aattttgtaa tccgggtttt
    87721 cggcgttaaa acgttgggcc agagaatcca cctctttacc cagttcccct tccatagaat
    87781 gccagaacgg aatggtcgtc actgcctgcg catttgccat taaagccagt ccgagcgcca
    87841 gtgctgaagc tgtataacgt aacggtttca ttgattatct ctcttgttgt accgaatgcg
    87901 cgaattcacg cgttttatgc tcgcggagta acatgacatg ctcgaattac agaaaaataa
    87961 ctattttgtt acatttttaa gatagtaagg tgtcagaaag atgacaaggc ggtgacggcg
    88021 cgggcgaggg aaaatgggag atggggcacg gataagcgga aaaatagaag gtctgaatca
    88081 aactctacag attactcatc gtttcatgcc ggatgcggcg taaacgcctt atccggccta
    88141 caagatcgtg caaattcaat atattgcaac tcacccagta ggcctgataa gcgcagcgca
    88201 tcaggcaatt ttacatttgt cacctgtctc aaaggagtct tttgactcct tatcaatcaa
    88261 cgtgttatta cccgcctaaa tatgcacttc tcactgcttc attcgccagc agcgcgtcgc
    88321 cggtatcgga gagcactaca tgaccgtttt ccagcacgta gccgcgatca gccagcttta
    88381 gcgcctggtt ggcgttctgc tcgacgagga agatggtcat cccctgctcg cgcagttgtt
    88441 cgatggtgtc gaaaatttgc tggatgataa tcggtgccag cccgagcgat ggctcatcaa
    88501 gcagtagcaa acgcgggtta ctcatcaaag cgcgaccaat cgccagcatc tgctgttcac
    88561 cgccagacat agtgcccgct cgctgaacac ggcgctcatg cagacgcgga aacagttcat
    88621 agacccactt tatgcgctcc tggaactggt cgcgttcggc aaaaaagccg cccatcgcca
    88681 ggttctcttc caccgtcatc cgcgagaaga cgcgacgccc ttccgggaca atcgctaccg
    88741 cttcgcgcat gattttcgcc gtctgccagt cggtaatgtc tttatcatca aacacaattc
    88801 gcccgctggt ggcgcgcgga tcgccgcata acgtgccgag caaggtggtt ttccccgccc
    88861 cgttcgcgcc aatgagggtg acaatctcgc cctgattgat atgcaggctc acctcatgca
    88921 gcgcctggat tttgccgtag tgggcgctga ctttgtcaaa ggacaacatg actttttcca
    88981 tcttatgcct cacctaaata ggcacggatc acatctgggt tattacggat ctgctccggt
    89041 gtaccgtttg ccagcggcat cccctgattg accacgtaaa ttctgtctga aatccccatc
    89101 accagcttca tatcgtgttc aatcaacaag atagtggtgt tgtgatggtt acgcagttcg
    89161 gcaatcagct catccagctc tttcgtctct ttcgggttaa gacctgctgc cggttcgtcg
    89221 agcattaaaa tctccggctg cgtcaccata cagcgggcaa tctccagacg gcgctggtca
    89281 ccataggcca ggttactcgc ctgacggttg gcatgttcca gcaaaccaat gcgctcaagc
    89341 caggtggcgg cgcggtcgag cgcttcgctc tgggcgcgac ggaaagaggg ggttttcaac
    89401 aggccggaga acagcccagt tttcagttgc tgatgctgtg ccaccagcag gttttcaatc
    89461 accgtcattt cacggaacag acgtacatgc tggaaggtgc gcaccacgcc catgcgggca
    89521 atttgctgcc ccggtaaacc ttccaggtgc tgatcgcgca gtaaaatggt gccgccggtg
    89581 ggtttataga atccggtcag gcagttgaag accgtggttt ttccggcacc gttagggccg
    89641 attaacgaga cgatctcctg cgggtacagt tcaagattga cgttgttcac cgccagcagg
    89701 ccgccgaagc gcatcatcag gccgttaaca gataataatg gctgactcat gcctgctctc
    89761 cttttgctgc gccgtttttc agcttgagtt gcgggcgcgt catgggcagc aagccctgcg
    89821 gacgccagat catcatcagc accatcaaac caccgagcat taacatgctg tattcgttga
    89881 aatcacgcat caactcgcgc gataccacca gcaaaacagc cgcaagaatc actgcaaatt
    89941 gcgagcccat accgccgagc accactatcg ccagcacaaa cgccgattcg gcaaaagtga
    90001 aggattcagg gctgacaaag ccctggcgcg cagcaaacaa cgttccggca aaaccggcaa
    90061 acgcagcgct gatggtaaag gcagtcagct tgatacgacg cgggcttaag cccagcgaac
    90121 gacaagcgat ttcatcttca cgcaacgctt cccacgcacg ccccagcggc atccgcagca
    90181 ggcggttaat gacaaacagg cttaacacca ctagcagcaa cgccaccagg tagaggaaga
    90241 tgacgcgatc ggagggatcg tatttcaggc caaagaaatt gctgaacgtg tcccagccgc
    90301 cttcgcgggc ggtacggctg aactcgagtc cgaagagcgt cggtttcgga atctgactga
    90361 taccgttcgg tccgccggta atttcggtgt tattgagcag caatatgcgc acaatttcgc
    90421 cgaacccgag ggtaacgatc gccagatagt caccgcgcag acgcagcacc ggaaaaccga
    90481 gcaggaagcc cgccgccgcc gccattaacc cggcaatcgg cagacaggtc cagaagccca
    90541 ggccgtaata gtgattgagc agcgcaaaag tgtaagcgcc gatggcgtaa aagccgccgt
    90601 atcccagcac cagcagacca gaaagaccaa caaccacgtt cagcccgaga ccgagaataa
    90661 tgtagatcat ggtcagagtg gcgatatcca ccgtcccacg cgacaccata aacggccacg
    90721 ccactgcaag caccagcagc gccacgagga acagtttctg cttcaccgtg gagccatcaa
    90781 tcgcgggcag aataaacttc ggcccggaaa cgctttttag ccctttctgg aaagcaggcc
    90841 gcacaagctg gaagaaaaag accaccgccg tgccgataaa cacccactgc caacggatct
    90901 ctgaagccgt gtcgaccacc agtttggtgc catccagctc cagttgcacg cccataaaga
    90961 cgcccgccag cacaaagaac atagcggcag agagcagcgc cattgcaata tgcatcggtt
    91021 tcatactttc tctacctccg ggcgacccag aataccggtc ggcatcacca gcagcaccag
    91081 gatcagcagg gcgaatgaga ccacatcttt atattccgta ctcagatagg cagaagagag
    91141 cgcctccgca atccccagga tcagcccgcc aatcatcgcc cccggaatgc tgccaatccc
    91201 accgagcacc gcagcggtaa aggctttcat cccggccata aagccgatgt aggggttaat
    91261 tacgccgtag aactgaccga gcagcacgcc cgccactgcc gccatcgccg cgccaatcac
    91321 aaaggtcagc gcaatcaccc ggtcggtgtt gatgccaagc aggctcgcca ttttcagatc
    91381 ttccgcgcag gcacggcagg cgcgccccat acgggaatag cgaatgaaaa tcgtcagcgc
    91441 cagcatggcg aggaaagtaa caatccatat caccgcctgc atggtggtaa tagacgcaga
    91501 gaagttttcg ctatggccca ccacccactg accgttaaac aggctgggca gcgccacatc
    91561 gcgcgaacct tcggtcaggc tgacgtagtt ttgcaggaag atagacatgc cgattgccga
    91621 gatgagtgca atcaggcgct tagagttgcg caccgggcga taggctaccc gttcgatact
    91681 ccagccgtag gcgctggcaa tgacgattgc gccgacgaat cccgccgcca ccagcagcca
    91741 gccggtatca atgcccagca tcatcagtgc ggcgatgatc ataaaggaga cgtagctgcc
    91801 aatcatgtaa acctcgccgt gggcgaagtt gatcatgccg ataatgccgt aaaccatggt
    91861 gtagccgatg gctatcagcg cgtaggtact gcccagcgtg acgccgttaa acatctgctg
    91921 caagaaatac aaaaactgct cagacataag gtaacctttc taaacccgcc cgtttttcac
    91981 ggacggtggg atgatcactt ggctgccgtg gatgaaccgt cggcgtgcca ctggaagaca
    92041 ccaaaatcga atcccttaag atcgcctttt tcatcccagt tcagcggccc aattacggtg
    92101 tttgcaccgt tagcttttaa atctttcacc agcgccagcg gctcatcgct gccggtacgt
    92161 tcaagggcag ttgccagaga ttgcaccgcc gcgtaggtga tccagacata gggcccggac
    92221 ggatctttct tgtcggcttt cagcgcatca acgatgccct ggtttgtcgg atcctggtca
    92281 tagcgttttg gcatggtgac caacatgcct tcagcggcat caccggcaat gttcgacagt
    92341 gacgcattac cgacaccttc cggccccata aactgggttt tcaggccaac ggaacgggcc
    92401 tggcgcagca tctgccccat ttccgggtag taaccgccgt agtaaacgaa gtcgatgttt
    92461 tcttttttca ggcgggcgat cagcgcggag aaatctttct ctccagcggt aatgccgtcg
    92521 aagaagacga cgttggcgtt agccgctttc agcccgtcct gcaccgaacg tgccagccct
    92581 tcgccatact gttgtttgtc gtgaatgatg gcgatgcgct ggggcttcac cgtctcaaga
    92641 atgtattttg ccgccgttgg cccctgggaa gagtccagcc cggcagtacg catgatgtat
    92701 tgataaccgc gttgggtcag ctccggattg gtcgctcccg gcgagatcat cagaatacct
    92761 tcgtcttcat agatatctga tgcaggttgg gtagaggagg aacacaagtg cccaataacg
    92821 tatttaatgc cgtcgttaac gattttgttg gcgaccgcaa cggcttgttt cgggtcgcag
    92881 gcgtcgtcat attccacgcc aaccagttta tcgcccttaa ttcccccttt ggcattaatg
    92941 tctttaattg cctgacgcgc gccgttaaat tccatatcgc cccactgggc aatcgggccg
    93001 gacatcgcgc cgacaacggc gactttaata tcgtcagcca tagcggtgtg tgaaattgcc
    93061 agtgcaatca tccctgcgat gatagttttc gcattccgtt tcatagtcaa aaatccccat
    93121 tcgtgatgtt gtgttgcttt gttcttatgt gttaacaaat cagactgttc ttttttatac
    93181 tgcactgttt ttacctgtct gattaagggt ttagcgcagt attttgtgat gatagcgatt
    93241 aaaatcccta tttttcagtc gat
//
LOCUS       DAFGPF010000005        87165 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFGPF010000005 DAFGPF010000000
VERSION     DAFGPF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 87165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87165
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.005"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1..608
                     /locus_tag="LSX49_000444"
                     /pseudo
     CDS             1..608
                     /locus_tag="LSX49_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525915.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(674..964)
                     /gene="ilvN"
                     /locus_tag="LSX49_000445"
     CDS             complement(674..964)
                     /gene="ilvN"
                     /locus_tag="LSX49_000445"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HBL7166908.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            complement(968..2656)
                     /gene="ilvB"
                     /locus_tag="LSX49_000446"
     CDS             complement(968..2656)
                     /gene="ilvB"
                     /locus_tag="LSX49_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HBL7166909.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVSASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFSIAQS
                     GRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEESIRDAAAMINAAKHPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPLVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYKQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNEADPQAALQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            complement(2762..2860)
                     /gene="ivbL"
                     /locus_tag="LSX49_000447"
     CDS             complement(2762..2860)
                     /gene="ivbL"
                     /locus_tag="LSX49_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HBL7166910.1"
                     /translation="MTTSMFNAKLLPTAPSAAVVVVRVVVVVGNAP"
     gene            3261..4445
                     /gene="emrD"
                     /locus_tag="LSX49_000448"
     CDS             3261..4445
                     /gene="emrD"
                     /locus_tag="LSX49_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HBL7166911.1"
                     /translation="MKRHRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVSTSSLMVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLIPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQ
                     PV"
     gene            complement(4453..4950)
                     /locus_tag="LSX49_000449"
     CDS             complement(4453..4950)
                     /locus_tag="LSX49_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBL7166912.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQLGIRSVQLI
                     PHLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDTTLQKWCGSEKS
                     QPRRDCQACDWHRLCPHAREDKPDNVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(4947..5309)
                     /locus_tag="LSX49_000450"
     CDS             complement(4947..5309)
                     /locus_tag="LSX49_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HBL7166913.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            complement(5299..5646)
                     /locus_tag="LSX49_000451"
     CDS             complement(5299..5646)
                     /locus_tag="LSX49_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HBL7166914.1"
                     /translation="MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLFIISLILMV
                     VAVIVMGLVLYAG"
     gene            complement(5706..7200)
                     /locus_tag="LSX49_000452"
                     /pseudo
     CDS             complement(5706..7200)
                     /locus_tag="LSX49_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
     gene            complement(7197..8912)
                     /locus_tag="LSX49_000453"
     CDS             complement(7197..8912)
                     /locus_tag="LSX49_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HBL7166915.1"
                     /translation="MNSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKA
                     PVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGI
                     ATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQLSDG
                     AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFM
                     QGIEQLTTVHAEKLNSVGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLA
                     EGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPLVGFFG
                     AVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVMV
                     APWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITI
                     NYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKTAS
                     IGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPD
                     AKDSL"
     gene            9079..9945
                     /locus_tag="LSX49_000454"
     CDS             9079..9945
                     /locus_tag="LSX49_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418136.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL7166916.1"
                     /translation="MNGKLQSSDVKNETPYNIPLLINENVISSGISLISLWHTYADEH
                     YRVIWPRDKKKPLIANSWVAVYTVQGCGKILLKNDEQITLHGNCIIFLKPMDIHSYHC
                     EGLVWEQYWMEFTPTSMMDIPVGQQSVIYNGEVYNQELTEVAELITSPEAIKNNLAVA
                     FLTKIIYQWICLMHAVGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLR
                     RLFLRYTGKTPKEYYLDARLDLALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKHKFG
                     YAPSAVLKNTDR"
     gene            complement(10035..11696)
                     /locus_tag="LSX49_000455"
     CDS             complement(10035..11696)
                     /locus_tag="LSX49_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HBL7166917.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGVGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMAMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESTRTNGGALIRTINIRVENPNLHN
                     LAIKDVPILNGDKVICSRLKREETLKVPSPETVIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASSD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFIHTLVDGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(11894..12322)
                     /gene="ibpB"
                     /locus_tag="LSX49_000456"
     CDS             complement(11894..12322)
                     /gene="ibpB"
                     /locus_tag="LSX49_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HBL7166918.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            complement(12434..12847)
                     /gene="ibpA"
                     /locus_tag="LSX49_000457"
     CDS             complement(12434..12847)
                     /gene="ibpA"
                     /locus_tag="LSX49_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HBL7166919.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     misc_feature    complement(12841..12913)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            13153..13485
                     /locus_tag="LSX49_000458"
     CDS             13153..13485
                     /locus_tag="LSX49_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HBL7166920.1"
                     /translation="MIKNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVLDTILLPWDVFRKDSSVRSRVEKSEADAQETNNVI
                     PPAKMPAN"
     gene            complement(13489..14703)
                     /locus_tag="LSX49_000459"
     CDS             complement(13489..14703)
                     /locus_tag="LSX49_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312656.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HBL7166921.1"
                     /translation="MKQITFAPRNHLLTNTNTWTPDSQWLVFDVRPSGASFTGETIER
                     VNIHTGEVEVIYRASQGAYVGVVTVHPKSEKYVFIHGPENPDETWYYDFHHRRGVIVE
                     SGKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERVSFTYNDHVMHELDPALDLRNV
                     GVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAF
                     IGDTLSPKGEKVPELFIVELPQDEAGWKVAGDAPLSGTETTLPAPPRGVVQRRLTFTH
                     HRASPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQ
                     SAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTENHANPPSADAVVFSPDGQWLAWM
                     EDGQLWITETDR"
     gene            14804..15904
                     /gene="cbrA"
                     /locus_tag="LSX49_000460"
     CDS             14804..15904
                     /gene="cbrA"
                     /locus_tag="LSX49_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance protein"
                     /protein_id="HBL7166922.1"
                     /translation="MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSK
                     PCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA
                     FDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM
                     VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAY
                     PMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG
                     FISASSLEGISYALDSAEILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA
                     PALRKWIMRSGVAHIPQLKDYPTRFTSPTSRM"
     gene            complement(15865..17202)
                     /locus_tag="LSX49_000461"
     CDS             complement(15865..17202)
                     /locus_tag="LSX49_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7166923.1"
                     /translation="MVSGFAMPKIRRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICY
                     VDRANLAVASAHIQEEFGITKAQMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIA
                     IFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
                     TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKA
                     ELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLT
                     WFPNYLTQEKGITALKAGFMTTVPFLAAFIGVLLSGWVADLLVRKGFSLGFARKTPII
                     CGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVF
                     NFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG"
     gene            complement(17277..18425)
                     /gene="dgoD"
                     /locus_tag="LSX49_000462"
     CDS             complement(17277..18425)
                     /gene="dgoD"
                     /locus_tag="LSX49_000462"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HBL7166924.1"
                     /translation="MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELSDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            complement(18422..19039)
                     /gene="dgoA"
                     /locus_tag="LSX49_000463"
     CDS             complement(18422..19039)
                     /gene="dgoA"
                     /locus_tag="LSX49_000463"
                     /EC_number="4.1.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HBL7166925.1"
                     /translation="MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTALDAGAQALKIFPSSAFGPQYIKALKAVLPPNIAVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            complement(19023..19901)
                     /gene="dgoK"
                     /locus_tag="LSX49_000464"
     CDS             complement(19023..19901)
                     /gene="dgoK"
                     /locus_tag="LSX49_000464"
                     /EC_number="2.7.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HBL7166926.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQGDHCLDSRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREENTPVVMAGMVGSNVGWKVAPYLSIPARFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARTLAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENAVDAFAAGLERGLNAPAVLPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVAHQQVITLVAGTSLTARYQQAFQAMGCDVTAVAGD
                     TAFQAGIRNIAHAVAN"
     gene            complement(19898..20587)
                     /gene="dgoR"
                     /locus_tag="LSX49_000465"
     CDS             complement(19898..20587)
                     /gene="dgoR"
                     /locus_tag="LSX49_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HBL7166927.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            20866..21522
                     /locus_tag="LSX49_000466"
     CDS             20866..21522
                     /locus_tag="LSX49_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166928.1"
                     /translation="MKLNFKGFFKAAGLCSLAFALTGCITWGLVSNTASRPHAEQWRS
                     DTIKGLSLAEDSNGTKGYVFVGESLDYLLTTGGDEVVNMLNDPAIHGERITVSDNAKF
                     ILSSSNKNFSGAITLYYDWNNEEDKALATQYGFICDTRRCTWMLDGLKGSIHQKNKKA
                     DYSNVMVFHQPFTVGFYEYKATDGVPRGLVNALLPVTLTLDIVTSPLQFLILCTTRNC
                     "
     gene            complement(21566..22378)
                     /gene="yidA"
                     /locus_tag="LSX49_000467"
     CDS             complement(21566..22378)
                     /gene="yidA"
                     /locus_tag="LSX49_000467"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBL7166929.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(22492..22890)
                     /locus_tag="LSX49_000468"
     CDS             complement(22492..22890)
                     /locus_tag="LSX49_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418153.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HBL7166930.1"
                     /translation="MGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGL
                     GAILSTWLSNQQSNQSVSGEQVESALGTNAVSDLGQKLGVDTSTASSLLAEQLPKIID
                     ALSPQGEVSPQANNDLLSAGMELLKGKLFR"
     gene            complement(23034..25448)
                     /gene="gyrB"
                     /locus_tag="LSX49_000469"
     CDS             complement(23034..25448)
                     /gene="gyrB"
                     /locus_tag="LSX49_000469"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBL7166931.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTETDLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(25477..26550)
                     /gene="recF"
                     /locus_tag="LSX49_000470"
     CDS             complement(25477..26550)
                     /gene="recF"
                     /locus_tag="LSX49_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBL7166932.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(26550..27650)
                     /gene="dnaN"
                     /locus_tag="LSX49_000471"
     CDS             complement(26550..27650)
                     /gene="dnaN"
                     /locus_tag="LSX49_000471"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBL7166933.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(27655..29058)
                     /gene="dnaA"
                     /locus_tag="LSX49_000472"
     CDS             complement(27655..29058)
                     /gene="dnaA"
                     /locus_tag="LSX49_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBL7166934.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            29355..29435
                     /locus_tag="LSX49_000473"
     CDS             29355..29435
                     /locus_tag="LSX49_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166935.1"
                     /translation="MTIDKKWLNRSNKDPGRSLRFTRQPV"
     gene            29665..29805
                     /gene="rpmH"
                     /locus_tag="LSX49_000474"
     CDS             29665..29805
                     /gene="rpmH"
                     /locus_tag="LSX49_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBL7166936.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            29822..30181
                     /gene="rnpA"
                     /locus_tag="LSX49_000475"
     CDS             29822..30181
                     /gene="rnpA"
                     /locus_tag="LSX49_000475"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBL7166937.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            30145..30402
                     /gene="yidD"
                     /locus_tag="LSX49_000476"
     CDS             30145..30402
                     /gene="yidD"
                     /locus_tag="LSX49_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBL7166938.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            30405..32051
                     /gene="yidC"
                     /locus_tag="LSX49_000477"
     CDS             30405..32051
                     /gene="yidC"
                     /locus_tag="LSX49_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL7166939.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            32157..33521
                     /gene="mnmE"
                     /locus_tag="LSX49_000478"
     CDS             32157..33521
                     /gene="mnmE"
                     /locus_tag="LSX49_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBL7166940.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGLKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            33763..33837
                     /gene="tnaC"
                     /locus_tag="LSX49_000479"
     CDS             33763..33837
                     /gene="tnaC"
                     /locus_tag="LSX49_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HBL7166941.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            34058..35473
                     /gene="tnaA"
                     /locus_tag="LSX49_000480"
     CDS             34058..35473
                     /gene="tnaA"
                     /locus_tag="LSX49_000480"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HBL7166942.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDNSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            35565..36812
                     /gene="tnaB"
                     /locus_tag="LSX49_000481"
     CDS             35565..36812
                     /gene="tnaB"
                     /locus_tag="LSX49_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HBL7166943.1"
                     /translation="MTDQSEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWISSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDSTSTTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHAGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            36944..38119
                     /gene="mdtL"
                     /locus_tag="LSX49_000482"
     CDS             36944..38119
                     /gene="mdtL"
                     /locus_tag="LSX49_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HBL7166944.1"
                     /translation="MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSALFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WTMATMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHNA"
     gene            38094..39053
                     /gene="yidZ"
                     /locus_tag="LSX49_000483"
     CDS             38094..39053
                     /gene="yidZ"
                     /locus_tag="LSX49_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HBL7166945.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSSVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNQLLDKPLHETPRGLKFELA
                     AESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLSIDYEVLFSDVPCVWLRKDHPALHEAWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSRNPKIVWLRETIKNLYASMA"
     gene            39210..39959
                     /locus_tag="LSX49_000484"
     CDS             39210..39959
                     /locus_tag="LSX49_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HBL7166946.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWELDGKHGWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKAFSPN"
     gene            39981..40547
                     /gene="yieF"
                     /locus_tag="LSX49_000485"
                     /gene_synonym="chrR"
     CDS             39981..40547
                     /gene="yieF"
                     /locus_tag="LSX49_000485"
                     /gene_synonym="chrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I chromate reductase YieF"
                     /protein_id="HBL7166947.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEDGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(40600..41937)
                     /gene="adeP"
                     /locus_tag="LSX49_000486"
     CDS             complement(40600..41937)
                     /gene="adeP"
                     /locus_tag="LSX49_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HBL7166948.1"
                     /translation="MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMSVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            42104..42769
                     /gene="yieH"
                     /locus_tag="LSX49_000487"
     CDS             42104..42769
                     /gene="yieH"
                     /locus_tag="LSX49_000487"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HBL7166949.1"
                     /translation="MSQIEAVFFDCDGTLVDSEVICSRAYVTMFREFGIHVDLEEIFT
                     RFKGVKLYEIINIISKEQGVTMIQADAEHVYRAEVARLFDSELEVIAGANELLASVKV
                     PMCVVSNGPVSKMQHSLGKLNMLHYFPEKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSSAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTHLSQLPELWKARGWD
                     ITA"
     gene            42836..43303
                     /locus_tag="LSX49_000488"
     CDS             42836..43303
                     /locus_tag="LSX49_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166950.1"
                     /translation="MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLWVIIH
                     PIFLLLSITTGAIPALLTGVMVACLPEKIGSQKRYRCLAGGIGGVVITEIYCAVIIHI
                     KVMASSVLFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS"
     gene            43352..43939
                     /locus_tag="LSX49_000489"
     CDS             43352..43939
                     /locus_tag="LSX49_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbrC family protein"
                     /protein_id="HBL7166951.1"
                     /translation="MTQNIRPLPLFKYHPKPLETGAFEQDKTVECDCCEQQTSVYYSG
                     PFYCVDEVEHLCPWCIANGSAAEKFAGSFQDDASIEGVEFEYDEEDDFAGIKNTYPDE
                     MLKELVERTPGYHGWQQEFWLAHCGDFCAFIGYVGWNDIKDRLDEFANLEEDCENFGI
                     RNSDLAKCLQKGGDCQGYLFRCLHCGKLRLWGDFS"
     gene            complement(44000..44722)
                     /locus_tag="LSX49_000490"
     CDS             complement(44000..44722)
                     /locus_tag="LSX49_000490"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL7166952.1"
                     /translation="MKLIITEDYQEMSRVAAHHLLGYMSKMRRVNLAITAGSTPKGMY
                     EYLITLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLT
                     IDNYREHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
                     HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASV
                     LQLHPSLMVIADKAAAAELALG"
     gene            complement(44737..45906)
                     /locus_tag="LSX49_000491"
     CDS             complement(44737..45906)
                     /locus_tag="LSX49_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBL7166953.1"
                     /translation="MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVN
                     TDNSVTFRYFAPGAKNVSVVVGVPVPDNIHPMTKDEAGVWSWRTPVLKGNLYEYFFNV
                     DGVRSIDTGTAMTKPQRQVNSSMILVPGSYLDTRSVVHGDLIAITYHSNALQSERQMY
                     VWTPPGYTGIGEPLPVLYFYHGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPD
                     TETDAKGIIPEDFVPQERRKVFYPLNAKAADRELMNDIIPLISKRFNVRKDADGRALA
                     GLSQGGYQALVSGINHLESFGWLATFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTV
                     VVGDKDVVTGKDIAGLKTELEQKKIKFDYQEYPGLNHEMDVWRPAYAAFVQKLFK"
     gene            complement(45933..47549)
                     /gene="bglH"
                     /locus_tag="LSX49_000492"
     CDS             complement(45933..47549)
                     /gene="bglH"
                     /locus_tag="LSX49_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-specific porin BglH"
                     /protein_id="HBL7166954.1"
                     /translation="MFRRNIITSAILLMAPLAFSAQSLAESLTVEQRLELLEKALRET
                     QSELKKYKDEEKKKYTPATVNRSVSANDQGYAANPFPTSRAAKPDAVLVKNEEKNASE
                     TGSIYSSMTLKDFSKFVKDEIGFSYNGYYRSGWGTASHGSPKSWAIGSLGRFGNEYSG
                     WFDLQLKQRVYNENGKRVDAIVMMDGNVGQQYSTGWFGDNAGGENFMQFSDMYVTTKG
                     FLPFAPEADFWVGKHGAPKIEIQMLDWKTQRTDAAAGVGLENWKVGPGKIDIALVRED
                     VDDYDRSLQNKQQINTNTIDLRYKDIPLWDKATLMVSGRYVSANESASEKDNQDNNGY
                     YDWKDTWMFGTSLTQKFDKGGFNEFSFLVANNSIASNFGRYAGASPFTTFNGRYYGDH
                     TGGTAVRLTSQGEAYIGDHFIVANAIVYSFGNDIYSYETGAHSDFESIRAVVRPAYIW
                     DQYNQTGVELGYFTQQNKDANSNKYNESGYKTTLFHTFKVNTSMLTSRPEIRFYATYI
                     KALENELDGFTFEDNKDDQFAVGAQAEIWW"
     gene            complement(47635..49029)
                     /gene="bglB"
                     /locus_tag="LSX49_000493"
     CDS             complement(47635..49029)
                     /gene="bglB"
                     /locus_tag="LSX49_000493"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglB"
                     /protein_id="HBL7166955.1"
                     /translation="MKAFPETFLWGGATAANQVEGAWQEDGKGITTSDLQPHGVMGKM
                     EPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEAEPNEAG
                     LAFYERLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
                     QHKVVLWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIP
                     EAKIGNMLLGGLVYPLTCQPQDMLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNI
                     TIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWG
                     WQIDPVGLRILLNTLWDRYQKPLFIVENGLGAKDSVEVDGSIQDDYRIAYLNDHLVQV
                     NEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGW
                     YAEVIKTRGLSLKK"
     gene            complement(49048..50922)
                     /gene="bglF"
                     /locus_tag="LSX49_000494"
     CDS             complement(49048..50922)
                     /gene="bglF"
                     /locus_tag="LSX49_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIABC"
                     /protein_id="HBL7166956.1"
                     /translation="MTELARTIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLK
                     KTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLGEKAQQAPENDDKGNLLNRFVY
                     VISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILG
                     YTAGKRFSGNPFTAMVIGGALVHPLILTAFENGQKVDALGLDFLGIPVTLLNYSSSVI
                     PIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPITFLLVGPLSTWISELIAA
                     GYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLIPLIINNFTVLGYDTMIPLLMPAIM
                     AQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGAL
                     GATIIGYAQTKVYSFGLPGIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLH
                     FITAKRQPAQVAQQEKTPEIITPEQGGICSPMTGDIVPLIHVADTTFASGLLGKGIAI
                     LPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNVG
                     DKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTVQINAGEPLLSIIR
                     "
     gene            complement(51055..51891)
                     /gene="bglG"
                     /locus_tag="LSX49_000495"
                     /pseudo
     CDS             complement(51055..51891)
                     /gene="bglG"
                     /locus_tag="LSX49_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418179.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator BglG"
     gene            complement(52177..52902)
                     /gene="phoU"
                     /locus_tag="LSX49_000496"
     CDS             complement(52177..52902)
                     /gene="phoU"
                     /locus_tag="LSX49_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBL7166957.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAEKDSDK"
     gene            complement(52917..53690)
                     /gene="pstB"
                     /locus_tag="LSX49_000497"
     CDS             complement(52917..53690)
                     /gene="pstB"
                     /locus_tag="LSX49_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HBL7166958.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(53781..54671)
                     /gene="pstA"
                     /locus_tag="LSX49_000498"
     CDS             complement(53781..54671)
                     /gene="pstA"
                     /locus_tag="LSX49_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBL7166959.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMIASITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(54671..55630)
                     /gene="pstC"
                     /locus_tag="LSX49_000499"
     CDS             complement(54671..55630)
                     /gene="pstC"
                     /locus_tag="LSX49_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HBL7166960.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(55716..56756)
                     /gene="pstS"
                     /locus_tag="LSX49_000500"
     CDS             complement(55716..56756)
                     /gene="pstS"
                     /locus_tag="LSX49_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBL7166961.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            complement(57070..58899)
                     /gene="glmS"
                     /locus_tag="LSX49_000501"
     CDS             complement(57070..58899)
                     /gene="glmS"
                     /locus_tag="LSX49_000501"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBL7166962.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(59061..60431)
                     /gene="glmU"
                     /locus_tag="LSX49_000502"
     CDS             complement(59061..60431)
                     /gene="glmU"
                     /locus_tag="LSX49_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBL7166963.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPIKKK"
     gene            complement(60785..61204)
                     /gene="atpC"
                     /locus_tag="LSX49_000503"
     CDS             complement(60785..61204)
                     /gene="atpC"
                     /locus_tag="LSX49_000503"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBL7166964.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(61225..62607)
                     /gene="atpD"
                     /locus_tag="LSX49_000504"
     CDS             complement(61225..62607)
                     /gene="atpD"
                     /locus_tag="LSX49_000504"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBL7166965.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(62634..63497)
                     /gene="atpG"
                     /locus_tag="LSX49_000505"
     CDS             complement(62634..63497)
                     /gene="atpG"
                     /locus_tag="LSX49_000505"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBL7166966.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(63548..65089)
                     /gene="atpA"
                     /locus_tag="LSX49_000506"
     CDS             complement(63548..65089)
                     /gene="atpA"
                     /locus_tag="LSX49_000506"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBL7166967.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(65102..65635)
                     /gene="atpH"
                     /locus_tag="LSX49_000507"
     CDS             complement(65102..65635)
                     /gene="atpH"
                     /locus_tag="LSX49_000507"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBL7166968.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(65650..66120)
                     /gene="atpF"
                     /locus_tag="LSX49_000508"
     CDS             complement(65650..66120)
                     /gene="atpF"
                     /locus_tag="LSX49_000508"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBL7166969.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(66182..66421)
                     /gene="atpE"
                     /locus_tag="LSX49_000509"
     CDS             complement(66182..66421)
                     /gene="atpE"
                     /locus_tag="LSX49_000509"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HBL7166970.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(66468..67283)
                     /gene="atpB"
                     /locus_tag="LSX49_000510"
     CDS             complement(66468..67283)
                     /gene="atpB"
                     /locus_tag="LSX49_000510"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBL7166971.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(67292..67672)
                     /gene="atpI"
                     /locus_tag="LSX49_000511"
     CDS             complement(67292..67672)
                     /gene="atpI"
                     /locus_tag="LSX49_000511"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HBL7166972.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
     gene            complement(68289..68912)
                     /gene="rsmG"
                     /locus_tag="LSX49_000512"
     CDS             complement(68289..68912)
                     /gene="rsmG"
                     /locus_tag="LSX49_000512"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBL7166973.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
     gene            complement(68976..70865)
                     /gene="mnmG"
                     /locus_tag="LSX49_000513"
     CDS             complement(68976..70865)
                     /gene="mnmG"
                     /locus_tag="LSX49_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBL7166974.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(71244..71687)
                     /gene="mioC"
                     /locus_tag="LSX49_000514"
     CDS             complement(71244..71687)
                     /gene="mioC"
                     /locus_tag="LSX49_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HBL7166975.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     SASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKIEAELKNSGAKQTGETLKINILDHNIPEDPAEEWLGSWINLLK"
     gene            complement(71777..72235)
                     /gene="asnC"
                     /locus_tag="LSX49_000515"
     CDS             complement(71777..72235)
                     /gene="asnC"
                     /locus_tag="LSX49_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HBL7166976.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            72387..73379
                     /gene="asnA"
                     /locus_tag="LSX49_000516"
     CDS             72387..73379
                     /gene="asnA"
                     /locus_tag="LSX49_000516"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBL7166977.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSKEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLEL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(73384..74835)
                     /gene="viaA"
                     /locus_tag="LSX49_000517"
     CDS             complement(73384..74835)
                     /gene="viaA"
                     /locus_tag="LSX49_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HBL7166978.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTLVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(74829..76325)
                     /gene="ravA"
                     /locus_tag="LSX49_000518"
     CDS             complement(74829..76325)
                     /gene="ravA"
                     /locus_tag="LSX49_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HBL7166979.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGALVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPASLQITDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC"
     gene            76548..78416
                     /gene="kup"
                     /locus_tag="LSX49_000519"
     CDS             76548..78416
                     /gene="kup"
                     /locus_tag="LSX49_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HBL7166980.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            78583..79002
                     /gene="rbsD"
                     /locus_tag="LSX49_000520"
     CDS             78583..79002
                     /gene="rbsD"
                     /locus_tag="LSX49_000520"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709562.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBL7166981.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAVIIAEEIKQHNPQLHETLLTHLEQLQQHQGNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            79010..80515
                     /gene="rbsA"
                     /locus_tag="LSX49_000521"
     CDS             79010..80515
                     /gene="rbsA"
                     /locus_tag="LSX49_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HBL7166982.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKLQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            80520..81485
                     /gene="rbsC"
                     /locus_tag="LSX49_000522"
     CDS             80520..81485
                     /gene="rbsC"
                     /locus_tag="LSX49_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBL7166983.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            81510..82400
                     /gene="rbsB"
                     /locus_tag="LSX49_000523"
     CDS             81510..82400
                     /gene="rbsB"
                     /locus_tag="LSX49_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HBL7166984.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            82526..83455
                     /gene="rbsK"
                     /locus_tag="LSX49_000524"
     CDS             82526..83455
                     /gene="rbsK"
                     /locus_tag="LSX49_000524"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL7166985.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDISPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKTLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            83459..84451
                     /gene="rbsR"
                     /locus_tag="LSX49_000525"
     CDS             83459..84451
                     /gene="rbsR"
                     /locus_tag="LSX49_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HBL7166986.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA"
     gene            complement(84417..85844)
                     /gene="mdtD"
                     /locus_tag="LSX49_000526"
     CDS             complement(84417..85844)
                     /gene="mdtD"
                     /locus_tag="LSX49_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
                     /protein_id="HBL7166987.1"
                     /translation="MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRS
                     PLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQL
                     VVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPVLGGVLVT
                     WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDTTGFLLFGLSLVLFSSGIELF
                     GEKIVASWIALTVIVTSIWLLLLYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRL
                     GTGCVPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGI
                     TVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGN
                     SVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLL
                     KTTDGNNLIKRQRKSKPNRVPSESE"
     gene            complement(85867..86559)
                     /locus_tag="LSX49_000527"
     CDS             complement(85867..86559)
                     /locus_tag="LSX49_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBL7166988.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMAALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDTIIQSDGDAAF
                     KACQALLRSPDK"
     gene            87040..>87165
                     /locus_tag="LSX49_000528"
     rRNA            87040..>87165
                     /locus_tag="LSX49_000528"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT        21313 a        22606 c        21776 g        21470 t
ORIGIN      
        1 ttaacttcga acgatactta gatacgtgga gataccgcgc agactctgag ttactgctac
       61 atattgctta ctgcgcaatt tttttcatgt cttttgtttt tgctgctatc ctaaattatt
      121 ttatctttgc cccgcgacat tacccaattc gttttaatag aaaaacagga aaggtctata
      181 tttgtaatta tattcttaat gatatgagtc ataaatcgac ctataccttc tggtagcact
      241 acccattcta caaacatact aagcctgaat ataaagagta cgactgggaa caaattcaag
      301 gtatagcttt ttttgcgcaa aatcaccatt ccacatacgc caccattcgc tgtattgttt
      361 atgaatcatt agacagtaca aatattattg acacctttaa cctgataacg acagagagtg
      421 ctacaaatgc attgcatatg acaaataaca aattatggtt atggattaat agctttatga
      481 attttgacga tgagttttta gagaaatcta tcaacactgc tccaggtatt tggggccgtg
      541 aagtgaattg gcctgatgat atgaataaga aatcaatgtt gtcttcaatg gacgaatata
      601 tactctgaat aatttgagtt gcagaatata agctcgcccg gatgtaaata tcccatccag
      661 gcgagaaaat cacttactga aaaaacaccg caatcttgtt aaacatcgtc gggtcggact
      721 gattacgctg cactttcacc acatcttcca gcttgtcgat ttggcttatc atctgctcca
      781 gacgctggtc gtcattgacc agtagccaga tgtggctttt gtcgctgtcc tgaatcggca
      841 ggcagagaat gccttcaacg ttaaaagcgc ggcgggcaaa aaggccacaa acgtgggtca
      901 ttacacccgg atgattgcga acggtgagct ccagaatcac gttatcatga gttgtgtttt
      961 gcatggctta ttcccccacc atttcagtat tcgccgcacc tggcggcacc atcgggtaca
     1021 ctttttcttc ggcatcaatg cgcacatgga tcagcgccgg gccagggcga ttgatgattt
     1081 cctgcaatgc agcctgcgga tcggcttcgt tattcaaatc acaggtttcg aggccgaatc
     1141 cggcggcaat ctgcataaag ttgattttgc ccggataggt agcggcaaaa acgccctgct
     1201 tgtagaacag actctgttgc tgatgcacca gccccagcgc ttcgttgttc atcaaaatga
     1261 ttttaacatc cagctgattt tcactggcgg tcgccatctc ctgaatattc atcatcaggc
     1321 tgccgtcgcc ggagaagcac aacactttgc ggtccgggtt cgccagcgcc gcgccaatcg
     1381 ccgcaggcag gccaaaaccc atcgtgccca gcccgccgga ggtcagccac tggcgtgggc
     1441 gattgagcgg ataggcttgc gcggtccaca tctgatgctg acccacgtcg gtagtgataa
     1501 tcgcattgtc atcgacacag gcggcaacgg cgttgatcag gccgtaatgg cttaatggat
     1561 cgcacgcttt cgggattgga cacgggaatt cacgctgcaa atccgccacc aactggtgcc
     1621 actctgcacg cggttgcgct tccaccagcg ggatcaactg cgccagcacg tcatcaacat
     1681 ccgcctgaat tgccacatgc ggttgcttga ttttgcccag ctctgcgcgg tcgatatcga
     1741 catgaataat tttggcattc ggacagaact gctctgtttt gccaatcgcc cggtcatcaa
     1801 aacgcgcacc gagtacaatc agcagatccg cctcctgcaa aatatagttg gtgctgcgca
     1861 caccgtgcat ccccagcata cccagcgaca gcggatgcgc ttttggcaac atacccagcg
     1921 ccattaaagt catggtggta ggcagttgcg ctttctccgc cagttcacgc actcgcgcag
     1981 gcgcgttgat cacaccacca cccagataaa gcaccgggtg tttggcggcg ttaatcatcg
     2041 ccgccgcgtc acgaatactt tcttcgctaa aggcgggtgc ggcggctttt tctgccatag
     2101 cgggctgtgt ttcaatctca aaaactgccg tttgcacatc cttaggaatg tctatccaca
     2161 ccgggccagg gcggcctgat tgcgcaatgc tgaaggcatc gctcatgacc tgcgggagtt
     2221 cttcgatatg tctgaccaga tagttgtgtt tggtgatggg gatagagatg ccgtaggtgt
     2281 cgacttcctg gaaggcgtcg gtgccgatca tcgaggcgga aacctgacca gtgatgcaaa
     2341 tcagcgggat ggagtccagc ctcgcatcgg caatggcggt caccaggtta gtcgcacccg
     2401 gtccgctaca ggccatacag accgccggtt taccgtcggt gcgcgccatt ccctgggcga
     2461 taaaccccgc cccttgttcg tggcgagcca gaatatggcg gatttgcgtg ctttggctta
     2521 aggcatcgta aacaggcagg atagaaccgc ccggaatacc cgtcacaatc ttaatgccct
     2581 gctgttccag gaaatgaacg ataaattctg cgccggtaaa gcgcttacgc gtcgatgttg
     2641 tgcccgaact tgccatgctc cagtcctttt cttctgggcc gactttccgg gaggtgctta
     2701 aacgaaaaac cccgcccggt ttgcgccggc ggggttttgg aatcgtgtgt tgttccagtc
     2761 cctacggcgc attgccgacg accaccacca cacgcacgac gaccactgcg gcggatggcg
     2821 cagttggtag tagttttgcg ttgaacatgg aagtagtcat tagggacctt gttggttttg
     2881 tgtttaacaa tatttataca agcacagctt tacaggggag acaatggaaa atttttcttc
     2941 cggataaaaa tacgtggcag atcacatttt gaactgaaac tcaggcaata aagcatcatc
     3001 acctgaaaga cggtcaggtt gttgacagag tgcgccttat tcatgtcgaa tacagcgtaa
     3061 acactttact ctaccaaccg caccaccact gtttccggca acatttattg ccgcttttgt
     3121 ttacatattc tgccgctaaa caattcccca ttcctggcgt atatctggct aacattcatc
     3181 aatgtgatag attcctctcc cgcatttatg ggaatgcgta gtgacttatt ctaattattt
     3241 ttataaaagc atccgtgata atgaaaaggc atagaaacgt caatttgtta ttgatgttgg
     3301 tattactcgt ggccgtcggt cagatggcgc aaaccattta tattccagct attgccgata
     3361 tggcgcgcga tctcaatgtc cgtgaagggg cggtgcagag cgtaatgggc gcttatctgc
     3421 tgacttacgg tgtctcacag ctgttttatg gcccgatttc cgaccgcgtg ggtcgccgac
     3481 cagtgatcct cgtcggaatg tccattttta tgctggcaac gctggtcgcg gtctcgacct
     3541 ccagtttgat ggtattgatt gccgccagcg cgatgcaggg gatgggcacc ggcgttggcg
     3601 gcgtaatggc gcgtactttg ccgcgcgatt tatatgaacg gacacagttg cgccacgcta
     3661 acagcctgtt aaacatgggg attcttgtca gtccgctgct cgcaccgcta atcggtggtc
     3721 tgctggatac gatgtggaac tggcgcgcct gttatctctt tttgttggtt ctttgtgccg
     3781 gtgtgacttt cagtatggcc cgctggatgc cggaaacgcg tccggtcgac gcaccgcgca
     3841 cgcgcctgct taccagttat aaaacgcttt tcggtaacag cggttttaac tgctatttgc
     3901 tgatgctgat tggcggtctg gccggaattg ccgcctttga agcctgctcc ggcgtgctga
     3961 tgggcgcggt gttagggctg agcagtatga cggtcagtat tttgtttatt ctgccgattc
     4021 cggcggcatt ttttggcgca tggtttgccg gacgtcccaa taaacgcttc tcaacgttga
     4081 tgtggcagtc ggttatctgt tgcctgctgg ctggcttgct gatgtggatc cccgactggt
     4141 ttggcgtgat gaatgtctgg acgctgctca ttcccgccgc gctgttcttt ttcggtgccg
     4201 ggatgctgtt tccactggct accagcggcg cgatggagcc gttccccttc ctggcgggca
     4261 ccgctggcgc gctggtcggc ggtctgcaaa acattggttc cggcgtgctg gcgtcgctct
     4321 ctgcgatgtt gccgcaaacc ggtcagggca gcctgggatt gttgatgacc ttaatgggat
     4381 tgttgatcgt gctgtgctgg ctaccgctgg cgacgcggat gtcgcatcag gggcagcctg
     4441 tttaagctca cgtcaccgca gcatcgtcat cagctccatg ggagaacgat gctgctttat
     4501 cagatcacgc atcacccgca tatgcggcgc ggagtaagaa taaaacgcct gatagcccgc
     4561 acaaagcacg ttgtctggtt tatcttcccg agcgtgcggg cacaggcgat gccagtcgca
     4621 cgcctggcag tcacggcgcg gttgcgactt ttcgctgcca caccattttt gtaaggtggt
     4681 gtcaaaaagt tcaatcgaaa tacgactgat atctgcccgc acccaacact cgaacagggc
     4741 aattaaaaat ttcccccaca gctctgctgt caccgaagcg gccgtcagat cgccccggtc
     4801 atcaaattca agatggggaa taagctgtac tgagcggatg cccagctgtt tgaaattgtg
     4861 ataaaaatcg gcaggttgca gagcatcctt atactctaca accagtttat gcctgtcctc
     4921 ttcagcatca atgacctgac ttcctgtcat gcgactctct caataaatac gataagttga
     4981 tgtatatgcg ttacagcaaa cagtattgcg agagataaca ccgcgaggga gatcaaaaat
     5041 ttgtcacgga ctacgtgaaa ttgggaaaaa tcgctattcg tgacatccat taaattgcga
     5101 ttacgggtgt agtgccagag gatcagcgcc acaatggcga ggatgccaat cgaaatccag
     5161 aataacatgc ccgcctggtg ccagttgtgt ttgatagcca acgccatcaa cgcgccgtag
     5221 cccagcatgg tacgaaacca cgccagtgat gtgcgttccg gctgcagccc tgggtcggca
     5281 atgcgtctgg ctttgcggct atccggcata caacaccagt cccatgacga tcactgccac
     5341 gaccatcaat attaagctga tgatgaataa gctgttggta tagggcaggt cctctttcag
     5401 gcgcatcgct ttttcattgc gtaaccagcg caagtagcca tacatcgcta acccgccgga
     5461 aaacagacac aacaacaacg ccagcagttc gcggatgacg ggcgtggcga aatctggcgc
     5521 aagttgatca agcccaaccc ccgccgccag aaatcctagt gcagtacgga tccacgccag
     5581 aaaagtacgc tcattagcca gcgagaagcg gtaatcgggc gcttctccga ggcgggaaat
     5641 tttcattgtt gctccttgta aactgttcct cgccgaaaaa ttaggccagg aacagcaata
     5701 atgcatcaga acttctgttt tttctcttcc accttcaccc cttgtgtcgg taaaccggtg
     5761 tcatagtcgc gtaccactgg agaataacca tcctgtgggc gtggacgaaa cgcccccatc
     5821 cagcgcggtt gtgcatcttt gcgccacgga cgcaggttcc attgataact gcggaacgga
     5881 tcgcgaattt tgtccatgta atccaataag gcgtcatgca ttttgctgcg aacgtcggca
     5941 aaatggatat catcgatcag gttatgcatt tcatttgggt cattacggcg atcgtaaagt
     6001 tcatcactgg tgaagaggtt gagcaccagt ttaaagtcat ccgttaccca gcaacgcacc
     6061 ggaataaaac cgccaaagct gtcatgctca atctcgtagc gattaaattc caccaacacg
     6121 ccacgtggtt cttttacggc aaggatattt tcccccggca gaatctctgg tttttcaata
     6181 tctgccagcg ccatcattgt cggcagtaag tcaatatgac tgactggcgt atcgacctgt
     6241 cgccgctccc cttgcggcga acggatgatc agcggaatgc gggtgatgtc gtcatacatc
     6301 gccgctcctt tactgatcag cttatgtgcg cccatcattt cgccgtgatc ggaggtataa
     6361 ataacccacg tattttcacg ttgctctggc gttaaggcgt tgatgacccg tccgatttgg
     6421 tcatcaacaa agtcattgca ggcaaaatag agcggatggt gataaagccc gtcatcaccg
     6481 actggcgatg gcatcgcctg cgcccataag cggtgatgtt ccggtttgtt cgccaggtca
     6541 tcctctgctt tctcacccag ttcgtagtaa aaatcagtgt atttctctaa atactccacc
     6601 ggacaggtga acgggtgatg cggctcatca tacgaaatca ccatcaggaa aggttcgtcg
     6661 gcgcgcgcgg gctgttgcag aaaatccacc gcccgattgc tgatgcggtg cgcccaggtg
     6721 aaggtttcgt caatatggtt cgcctgtaaa tcttcgacgc tgtttaggcc attgcgccac
     6781 aggctaatct ctttttccgt cagttcacta agatagttcg ccccatcgaa ccagtaatca
     6841 gcgtcccact ccggcggaca ctcgccaggt gccgaaatag tcatgaccgt cgagatgcca
     6901 tttgccgatg taacaggtgt gatagccggc atccttaaag tagcgcccca tagtggagat
     6961 gtttttgcct ggcgcgacgt tgttggtcca cgggccggac tggttagcgt agataccggt
     7021 gaatagtccg gcgcgtgcag gcgtacaaac cggtgaacag gtgtaggcgg agttaaagcg
     7081 aataccttcc gccgccagac tatcaatatt ttgcgtattc agcggcttac cgctatagca
     7141 accgaccata ttggtggcct gggtatcggt catgatgaac agaaaattgg ggcgtttcat
     7201 aggctatcct ttgcatcggg agtaaaggtt acggctgggt cgtgacgatg ccgccagctg
     7261 tcaaaaatca ggtagacaat cactacggcg gcaatgaaat aactgatcat cgctaaccag
     7321 cgcgtaccgt agccgccgaa ttcagccagc ccggcataga cgccaatcat cgcgaacagg
     7381 ataccaattg acgcagtctt gacgtttttc cacggtttca tgtccaccgc aaacgcatct
     7441 ttgaaggtga acggcgtggc gcgcggtttg ataaaaccga tcaccagcat cacgaccacg
     7501 ttgatgcaga acgtacaggc cagcacatag aggaaatgga agtcgaactt caccagatag
     7561 ttgatggtga tgtagctgat tatgccaatc cccatcgcca cttttgccgc cagcgccgga
     7621 atgcgcggga agaaaaagcc cataatgatg atggtaacca gcggcacgtt gtaaataccg
     7681 ttgagctgtt tcatccagct atacagcccc tgcggcgcgt tggcgatcca cggcgcgacc
     7741 atcaccgaaa cgatggcgat aaagaaacca aatttgcgcc cgacggtgac cagctgttgc
     7801 ggctcggcat tctggttaat gatacgccgg taaataccca tactgaataa cgtactggcg
     7861 ctattcagaa agccgttgaa ggtactgatc accgcaccaa ataacaccgc accgaagaag
     7921 cccaccagtg gcaccggcag aacgttattg accagcgtcg ggtaggccat gtcggctttc
     7981 ggtaaatcct gatacagatg aaacgcaatc aaccccggca gcaccagtac cagcgggtcg
     8041 agcattttca gcaccgccgt taacagtgcc cccttttgcc cttccgccag gctttttgac
     8101 gccagcgtgc gttgcacgat gccctgattg gtacaccagt aaaaggtgtt aaccagaatc
     8161 aaaccggtaa atgccgcgcc aatcggcaag ggatcggtcg ggccaccgac tgagtttaat
     8221 ttctcggcgt gaacggtggt aagttgctca atgccctgca taaagctgcc cttgcccatc
     8281 gcgatcaggc caaataccgg caccatcaac ccgccaataa ccagcccaat accattgatg
     8341 gagtccgcca ctgccattgc gcgcagtccg ccgatcaccg catacaaaat tcccgccaga
     8401 ccaagcaaaa taaccagtaa ccagatagcc gcaccatcgg aaagttgtag cgactcaccc
     8461 acatgaaaca ggctgttgag cgccaacgcg ccggaataga gaacaatcgg cagaaagcag
     8521 acgccggtgg caatgaggaa gcagaagtcg atgataatac gcgtcgtttt atcataacgt
     8581 tcctccagaa aatcggggat ggtggcaatg ccgcgcttca gatagcgcgg taaaaagatt
     8641 agcgcgagga agatcagcgt cactgcagag gtgacttccc agcccatcac cgacatgccg
     8701 cttttgtagg cctgcccgga aaggccgacc agttgttccg tggaaaggtt ggttagcatt
     8761 aacgaagcgg caataaccgg cgcttttagt gaacgtccgg caagaaaata gccttgttgc
     8821 gatccggtat ctgttttacg gaccttccac caggtgatga ccgccaccag cagcgtaaaa
     8881 ccgacaaaac tcaagatttg taacgaattc atctcatagc ccttatttat gtttatgtcc
     8941 cggacgcatg aatataggga gaggtaaaat gcgtcgggtc aggcagtcag attcttaaaa
     9001 tacaaacgtc gtatccctga acggattgtt ttctgttaag ttcaggttgt gagcataatt
     9061 cgccggaggg atattaaaat gaatggaaaa ttgcaaagtt cggatgtaaa aaacgaaact
     9121 ccgtacaata ttcccttatt gattaacgaa aatgtgatct ccagcggaat ttctctgata
     9181 tcgctctggc atacctacgc cgacgagcat tatcgggtga tctggccgcg ggacaagaag
     9241 aaaccgctta tcgccaactc atgggttgcg gtgtataccg tacaaggatg tgggaaaatt
     9301 cttttaaaga atgacgaaca aataactctg catggcaact gtattatatt tttaaagcca
     9361 atggatattc actcttatca ctgtgaaggt ttggtctggg aacagtactg gatggaattt
     9421 acccccacca gtatgatgga tattcccgtc ggtcagcaaa gcgttattta taatggcgaa
     9481 gtttataatc aggaacttac cgaagttgct gagttaatta cttcaccaga agcaataaaa
     9541 aataatctgg cagtcgcttt tctgacgaaa attatttatc agtggatttg tcttatgcac
     9601 gcagtcggta aaaaagatcc acaacggcgg caaattgaaa aattaattgc cactttacat
     9661 gccagtctac aacaacgctg gagcgtagct gatatggctg ccacgatccc ctgtagcgag
     9721 gcctggttgc gtcgtctgtt tttacgctat accggcaaga cgccgaaaga atattacctc
     9781 gatgcgcgtc tggatctggc gctatcgcta ttaaagcaac aagggaactc ggttggcgaa
     9841 gtcgctgata cgctcaactt cttcgactcc tttcatttca gcaaagcctt taagcataaa
     9901 tttggttatg cgccgtcagc tgtgctgaag aatacggaca ggtaataacc agaatggcga
     9961 gtgtgtaaat gactcgatga tgttcagaaa taccaggcgg agtaccattt acggcgactc
    10021 caccgggaaa agagttaacc gatactccag aagagcaccg ccagtaattg gggtgtgata
    10081 atgcgcagga acatcactaa cggatagaca gtggcgtaag agagcgccgc tgcaccgctg
    10141 gttggatgaa gattattagc aaacgccagc gccggaggat cggtcatgga acctgccagc
    10201 atcccgcaca tggtcaggta attcattttg gctaacatcc gcgccagaat accaacagta
    10261 atcagcggaa cggcggtgat cagggcacca taaccaatcc agcttagccc ttcgccatcc
    10321 accagtgtat ggataaaatc gccgccggat ttcaggccaa cgaccgagag gaacagtacg
    10381 atccccagct cccgcagcgc gaggttggcg cttggcggca taaaccagta cagcttgccg
    10441 atactgccga tacgcccgag aatcaacgcc ataatcagcg gaccgcccgc cagccccagt
    10501 ttcaacgcgg ccggaaatcc cggcacaaag acgggaatag aacctaacaa tacgccaagc
    10561 ccgataccaa taaacactgg cagcatctga acctgttgca gtttttgctg cgcattcccc
    10621 agcacattgg caacggcatc aattgcggac ggacgcccca ccaggttgag gatatcgccg
    10681 aactgcaggc tgatatcgct acttgcaact aattcaacac cagcacggtt caggcgcgag
    10741 ataacaacgt catagcgttc tttaaagtgc aggtcgcgaa tacgtttacc gagcacgttt
    10801 tcattggtga ccaccacacg ctcgacgcgc aaatcagtgc ctttcgtaga cagcgaggta
    10861 tcgacctcct gaccaatcac cagttgcgca ttatgtaaat ccgcaggctg ccccaccaga
    10921 tgcagcaaat cgcccagttg aataacggtt tctggcgaag gcacttttag ggtttcttct
    10981 cgtttcaatc gtgagcaaat aactttatcg ccattgagaa tcggcacatc tttaatggct
    11041 aaattatgca aattaggatt ctcaactcgg atgttaatcg tcctgattag cgcaccgccg
    11101 ttggttcgcg tggactcgtg ctgctgggcc tcagtctcaa cattgacgcg gaaaataacc
    11161 cgcagcatcc acatagtgaa caaaatgccg caaatcccaa atggatacgc catcgcatag
    11221 ctcatcccca tttgatcgac catcgccatc ggtgtcccca ggtcgcgcaa gatctgctgc
    11281 cctgccccca gcgctggcgt attggtgacc gcgccggaaa aaatccccag cacgaccggc
    11341 agtggaatat caaacagttt atgcaggatg gcggtaacca gaccaccgat gatgacgatc
    11401 agaacagcaa acaggttgag gcgtaatccg gagacgcgca atgaggcaaa gaagcccggc
    11461 cctacctgaa tcccgatggt ataaacgaac aggatcaggc caaattcctg aataacatgc
    11521 agcatatcgc tacttaatgt catccccgcc tgagaaacaa aatggccgac gatgatcccg
    11581 ccgaacagca cgccgccaat gcccaatcca acaccgcgaa acttgacgtt gccgataaac
    11641 aacccgacga ccgccaccaa agccagaata ctgaccgtta atgctatatc actcatcgtc
    11701 catttctctt gaaataacat tttaattgct acggattatg gctgaatcgg tgaagcagat
    11761 ttgccttata gcgcacatta tcacgggaaa gaacgtgccg aaatatctta aacaggcgaa
    11821 atttaacgca ttgttgaaga aaaaagacaa aaaaaaagcc ccaccagaat ggcggggcaa
    11881 agagaatagc tagttagcta tttaacgcgg gacgttcgct gatagcgata cgctgcgctg
    11941 cgatgggttc aggctcatta cgaattaaat caatatgcag taaaccgttt acgaaggttg
    12001 cgccagagac ttccatattt tcagccagcg taaagctcag gctaaaaggc tgattcataa
    12061 gcccttgatg cagccatttt ttctcttctt ttggctgctc cggtgtgcct tttacgctca
    12121 ggcgcgtacc ttccagttga atctctaaat cttcctgacg aaaacctgcc agcgcgaggg
    12181 taatgcggta gtggttatcg tcgcttttct caatgttgta cggcgggaag ctctggcttt
    12241 caccggcgtt ttgcagtgcg ttggccagtt tgtcaaaacc gatccattga cgcatcagtg
    12301 gggataaatc gaagttacgc atagtcattt ctccttctaa gaagcgagta agtacctgca
    12361 aatccgaaga ttcgcatatg ctccctgacg gcgagcatgg agatgtcagg ccgcgccagg
    12421 cggccttagg gaattagttg atttcgatac ggcgcggttt tttcgcttcc ggaatcacgc
    12481 gttcgagatc gatatacagc agaccattca ccaggttagc accacgaaca tgaatgttct
    12541 cagctaactg gaatttacgt tcaaagttgc gttcagcgat gccctggtac agataggtgc
    12601 gctctttttg ttcgtcggcg tgagcacctt tcaccaccag cagattatcc tgggcggtaa
    12661 tttccagttc gctctcagca aaaccagcca cagcgatagc aatgcggtaa tggttttcgt
    12721 ctaccagttc aacgttatac ggagggtagc cgccattact ctggctctgg ttgttttcta
    12781 agtggttaaa caaacggtca aatccaatag cagaacggta aagcggggat aaatcaaagt
    12841 tacgcataat caatagctcc tgaaatcagc gagaatctaa gaccttccac aatggacagg
    12901 tcaggtagcc agaacaccca tcaggcgcgt cctcatcggc tacgatgtaa aaatgggtct
    12961 ggaaatgaac ttttcaagcc ttatcagcgg actttttttt gcagtttatg gtctattgca
    13021 tagactgagg gggcagcacg aaacgttaaa gtgcgatagc cgccacagtg cgacgtaatg
    13081 atgatgttat tttcagcaag ggatcgctat aactcatcag gccaacaccc acgatcaaca
    13141 gatgaattta ttatgataaa aaatgtgttg ttagcgttca tgatatgcag cggaatgaca
    13201 ttactcggag gatgctccag cgtgatgtcc cataccgggg ggaaagaagg aacgtatcct
    13261 ggcacccgcg ccagcgcaac catgattggc gacgatgaaa ccaactgggg cacaaaatcg
    13321 ctggcgatac tcgacatgcc atttaccgca gtactggaca caatattgct accgtgggat
    13381 gtgttccgca aagacagctc agtgcgctcg cgcgttgaaa aaagcgaagc cgacgcgcaa
    13441 gaaaccaata acgtcattcc ccccgccaaa atgcctgcaa actgagagct agcggtcagt
    13501 ttcggtgatc cacaactgac cgtcctccat ccacgccaac cattgaccat ccggcgagaa
    13561 aaccacggcg tccgcagaag gtggattggc gtggttttcg gttaaatact caacctcgcc
    13621 gctttgcgca tgggcacaag caatccgatt atccagcaca aatcccagcc attcgcctga
    13681 tggatgccag ttaaatgcag actgaatatc cgttttatta tgggttaact ggcgtggttc
    13741 accgccctgt ggcgagataa gccacagttg cacaatgccg ttatcatcac gcattaaaaa
    13801 cgcgatttgc gtaccctgcg gattacagcg cacccagtgg cgcgggacgt tgactaatcc
    13861 cggagaagcc cgatggtgcg taaaggttaa acgtcgctgc acgacaccac gcggtggcgc
    13921 gggcagggtt gtttccgttc cacttaacgg cgcatcacct gccactttcc agccagcttc
    13981 atcttgcggc aactcgacaa taaacagctc cggcactttc tcgccctttg gcgaaagtgt
    14041 gtcgccaata aacgccagcg cgtgatttcc tacccatcct tcttcataag cacgattgat
    14101 ttcatcactg ccaggctgtg gcgtgggcgt ggttttactt accagcacgc accagtggct
    14161 accgctgtat tcacgcggat gctgcttttg tacgttgacc gggccaaacg gtgcagcaac
    14221 accgacattt cgcaaatcca gcgccggatc gagttcatgc attacatggt cgttgtaggt
    14281 aaagctcacc ctttcaccgt ttgggctaaa gacatgtaca tgactgccgc cgcgcagcgc
    14341 tcctggcgta tatggcgcgg taatatccat tgcatcgaga ttgctcacct tgccgctttc
    14401 aacaatcact ccgcgccgat gatgaaagtc gtaataccat gtttcatcag gattttccgg
    14461 gccgtggatg aagacatact tctctgactt cggatgaacg gtcaccacgc cgacgtatgc
    14521 gccctgtgac gcgcgataga taacctcgac ctcgccggta tggatattca cacgctcaat
    14581 ggtctcgccg gtaaacgacg ccccagaagg ccgcacgtca aacaccagcc actggctgtc
    14641 gggcgtccag gtattggtat tggtgagcag gtgattacgg ggagcaaagg ttatctgttt
    14701 catggcgcgg tcctgataca aaacggttcc cgccatcata cttcacaagg acttcacttt
    14761 cagacaatag tcttttgcca tcgtgatgaa tgtgagtgaa aagatggaac atttcgacgt
    14821 ggcgattatt ggcctcggcc cggcagggtc ggcgttggcg cgaaagttag caggcaaaat
    14881 gcaggtgatc gcgctggata aaaagcacca gtgtggtact gaaggtttca gcaaaccttg
    14941 tggcggtctt ctggcaccgg acgcgcagcg atcttttatt cgcgatggac tgacgcttcc
    15001 tgtcgatgtc atcgccaacc cgcagatttt cagcgtcaaa accgtcgacg tcgccgcatc
    15061 gctcacgcgt aactaccagc gaagctatat caatattaat cgccatgctt tcgacttgtg
    15121 gatgaaatcg ctgatccccg ccagcgttga ggtttaccac gacagcctgt gtcgaaaaat
    15181 ctggcgtgag gatgataaat ggcatgtcat ttttcgcgca gacggctggg agcagcatat
    15241 taccgcccgc tatctggtcg gtgccgatgg tgccaactcg atggtgcggc gacatctcta
    15301 cccggatcat cagattcgta aatatgtcgc catccagcag tggttcgcag agaaacatcc
    15361 ggtaccgttc tactcctgca tctttgataa tgcgataact gactgttact catggagtat
    15421 cagcaaagac ggttatttta tctttggcgg tgcctatccc atgaaagacg gtcagacgcg
    15481 tttcacgacg ctaaaagaga aaatgagcgc ctttcagttc cagtttggta aggcggtgaa
    15541 aagcgaaaaa tgcacggtgc tgtttccctc acgctggcag gattttgtct gcggcaagga
    15601 caacgccttt ctgattggcg aagcggcggg atttatcagc gccagctcgc tggaggggat
    15661 tagctatgcg ctggatagcg cagagattct gcgttcggta ttactgaagc agccagagaa
    15721 gctcaatacc gcttactggc gcgccactcg caaactgcgt ttaaaactct tcggcaagat
    15781 agtaaaaagc cgatgcctga ccgcaccggc tttaagaaag tggattatgc gcagtggagt
    15841 ggcacatatt ccacagttga aagattatcc aacgcgcttc acatcgccca ccagcaggat
    15901 gtaagagagc gcgccaatca acgcgacggc ggagatataa accagtgcag gcgcgaaacc
    15961 gtaaccctgc gccaggtacc ccaccaccag cggaacggtg atgccgccca gaccaccggc
    16021 aaagttaaac acgccgccgg ttaaaccaat caggcgcatc ggtgccagag aagagaccag
    16081 cgaccaggtt atcgaagcaa aaccgttgcc gaagaatgcc agcgccatca ggcacataat
    16141 catcatcgga tcgttggtgt agttcgcacc cataatgcag gtggagatca gcaagccgca
    16201 gataatcggc gttttacgcg caaagcccag tgaaaagccc ttacgtacca gcagatccgc
    16261 gacccagcca gagagcagga cgccaataaa cgccgcgagg aatggcaccg tggtcataaa
    16321 acctgctttc agcgccgtga ttcctttttc ctgggttaaa tagttcggga accaggttaa
    16381 gaaaaaccac agtgtagaag ccaccgcaaa ttgcccaaga tagacaccga tcagtttacg
    16441 atggaacacc agtttccagt ctttggctgt taacggctga cgcgcctctt ttttcaccgg
    16501 cgcatcgcca tccaccagac cgccgccatc acgaatgtaa tccagttcag ctttgctgat
    16561 gcctttggtc agacgcggcg gctgataaac cttaaaccaa atcagcgacc agataatgcc
    16621 gataccaccg gtgacaatga acacccagtg ccagctcaac atctcctgaa tccagatcag
    16681 cagcggagtc agaaacgcca gaccgacaaa ctgaccagac gtataaaaac caacggcaga
    16741 agcgcgttca tgttccggga accaactggt taccatccgg ttattggtcg ggaacgcggg
    16801 cgcttcgaaa ataccggtta tcgcgcgcag accaattaat gacattaagc ccgtggcaaa
    16861 gccctggaat aacgtcgcca ctgaccagcc aaatatcgca ataaaataag tcacgcgtga
    16921 acctacgcga tctaaaaacc aaccgccggg gatctgacat agcgtataaa gccaggcgaa
    16981 ggccgaaaat acatagccca tttgcgcttt agtaatacca aactcttcct gaatatgggc
    17041 agaagccacg gccaggttag cacggtcaac ataacaaatg accaccgtaa taaagatcat
    17101 caccagcgtc agataacgcc gacgccccgg ctttgctgca ttaacgggaa tatccatagc
    17161 gagctttctc ctgattttgg gcatagcgaa gccgctcacc atgcactgta atttacagag
    17221 ggttatattt ttgtattgct gttttagtgc ccgatgaggg gcttacgtgg caggaattac
    17281 cactctgcta cgctgttatc ttcatgacgc cagagcggat tacgccagtc cggggcattt
    17341 ttactgaact caataacttt agcttcgtcg atttccacgc ctaagcccgg tttcgttaat
    17401 ggtttaaaga aaccgccgac catgctgaag tcctctttgt ttttcacaaa gtcgagtaac
    17461 tccgcgcctt tgttgtaatg aatgcccata ctttgttcct gaaggacggc gttataggaa
    17521 acaaagtcga tatgcaggca agccgccagt gcaatcggtc cgagcggaca gtgcggcgca
    17581 agggtcacgt cataggcttc tgccattccg gcaattttgt agcattcggt aataccgcct
    17641 gcgtgggaga gatccggttg cagaatcgaa ataccgcctg cctccagcac acgtttaaaa
    17701 tcgaagcgtg agaacatgcg ctcacccgcc gccagtggaa tatgcgtttg tgccgccagt
    17761 ttcgggtagt attcggcctg ttccgccagc accggctctt caataaacag cggacgatac
    17821 ggttccagct ctttaatcag cactttcgcc atcggcgcgc tgacgcgacc atggaagtcc
    17881 agaccaaact caatctgatt gccaaaagct tcacgaattt gtgccacggt gttgactgcc
    17941 gcatctaccg cgcgggagtt atcaattagc cccagttctt cacaaccgtt cagtttgaag
    18001 gtatcgaagc cgatttcgcg tagcgtttta atgccgtcga taacatccgc cggacgatcg
    18061 ccgccgaccc aactgtaggc tttaattttg tcgcgaacca ggccgcccat cagttgccag
    18121 accggcgcat tcagcacttt gcctttgata tcccataaag cctggtcgat cccggcgatg
    18181 gcactcatca gaatcggacc gccacgataa aatccggcgc gatacatcac ttgccataag
    18241 tcgttgatgc gtgacgggtc ctgaccaatc aaatagtcac tcagctcgtg gactgccgct
    18301 tccaccgtgc gagcgcgacc ttcaatcacg ggctcgcccc aaccgaccac gccttcatcg
    18361 gtttcaattt tcaggaacat ccagcgggga ggtaaacgat acgtggtaat tttggtgatt
    18421 ttcattgcac tgcctctcga tacgccttaa caaatgctgc tgcctgctgc gcagtccgtt
    18481 ctacggactg cccggcgcga tagagatcgc tacctaagcc cgctccggca cagcctgcat
    18541 ctatccactg cgccaggttt tctggcgtca caccgccaac ggcaaagacc gcgatgttcg
    18601 gtggtaatac cgcttttaat gctttgatgt attgcggacc aaaagccgat gacggaaata
    18661 ttttcagtgc ctgcgcaccc gcgtcgagcg cggtaaaggc ttcggtcgcc gtcgcgcagc
    18721 cggggcagac ggtcatgccg tagcccaccg cacggcggat cacttcacta tggatattgg
    18781 gcgtaacgat gagctgacag cccattctgg cgagcgcatc gacctgttca ggtttcagta
    18841 ccgtacctgc gccaatcaac gccttgtcgc catacgcatc aacgatggcg ggaatgctct
    18901 gctcccattg tggagaattc agcgggattt caaccgcgtc gaacccggcg tcaatcaccg
    18961 cgccaacatg cgccagcgcc tcgtcgggcg taatgccgcg caaaatggcg atcagcggga
    19021 gtttagtttg ccactgcatg agcgatgttc cttataccag cctgaaatgc cgtgtcgccc
    19081 gccaccgccg tcacgtcaca acccatcgcc tgaaaggctt gctggtagcg cgcggtcagc
    19141 gatgttccgg cgacaagggt gatgacttgt tgatgggcca catagtcgcg catactggcg
    19201 acctctgcgc caatcaacaa accagagaga aattcgctga cctgttcgcg gggaagtgtt
    19261 cccagcacat gcgaggcgcg aacttcaaaa agctgtggca atacggcggg cgcattaagg
    19321 ccacgctcaa gaccagccgc gaaagcatcg acagcgtttt cctgcggcgg caaacctgcg
    19381 ccaatcaatg agtgatttaa cagtaaatga tgtaattcac cggtcatcac ggtgcgaaaa
    19441 tcgttaattt gctggctatc ggcctgcacc catttgcaat gcgtaccggg catgacataa
    19501 agagaggaag gagcgagagt gcgcgcgccg atcaattgtg tttcttcgcc acgcatcaca
    19561 ttgtggttat cgtcatgaga gacgcataat ccgggaataa tccagatatt gtcgccaaca
    19621 gacgttaatt gttcgccaat agacgaaaaa cgggcaggaa tggataaata cggcgcaact
    19681 ttccagccga cattgctgcc gaccattcct gccattacca ctggcgtatt ctcttcacgc
    19741 cagtcggtcg tcacttctgc taacaccgca gccggagatt ttccattcag gcgcgtgacg
    19801 cctgcttctg attgcctgct gtccaggcag tggtcgccct gataaagcca ggcgcgcaga
    19861 ttggtcgatc cccagtcaat tgcgatgtag cgagctgtca tgtgatttcc tttaaccttc
    19921 gtgtcgagct ggcgatcatg gtaagcgccg cctgctctgc cgcatcgccg tcctgatgcc
    19981 ttatcgcatc gaacagcgcc ttatgttcct ggagcgtttg cggcatgttg gcctcatcgc
    20041 ccatccaggt tcgttcaaaa accgcccgct gcagcgaact gatcgcaatg ctcagttgtt
    20101 gtaacaccgg gttatgcacc gactgcagca ccgcctcgtg gtagcgaata tccgcttcgt
    20161 taaacgcttc gcggtcctga ttgttagcaa tcatctcgtt cagcgccgat tcaatctgcg
    20221 ccagatcgct ggaggtcgcg cgctctgctg cccaacgggc aatagccggc tctaccaggt
    20281 ttcgcacttc gctcattgca ctgataagcc gtgggtcata gtcgttttcc agcacccatt
    20341 gcagtacgtc agtgtcgagg taattccact ggttacgcgg agccacaaac gccccgcgat
    20401 aacgtttcat ttcaatcagc cgcttcgcca tcagcgaacg aaatacctca cggatgatgt
    20461 tgcgcgaggt tgcaaactcc tcacagagtt ctgcctcagc cggaagcggc gagcctggca
    20521 cgtatttgcc gtgaacgatc tgtttaccca gcgtaataac gatgcgatcg gttttattga
    20581 gagtcatgga gagtccttgt gctctgtatg ttcctctcta ctttaccccg atcgatgcat
    20641 aacgcggcaa ttttgtagta ccagcgtgat gacgttcgcg tttgctgtgc gcataatgta
    20701 gtacaaattt atattgttgt actacaattt agatcacaaa aagaacaatc cataagaaaa
    20761 tgttctacgt cgggcaaaaa tctgaaaagg gagatcaggc gctaaacagg agggaaagaa
    20821 gagtatgctt tcaacggctt agcactcttg tttaaaggat taatcatgaa attgaatttt
    20881 aaaggatttt ttaaggctgc cggtttgtgt tctttggcat ttgcgttgac cggatgtatc
    20941 acctggggat tggtttccaa tactgcaagc cgtccacatg ccgagcaatg gcggtcagac
    21001 acgattaagg gtttatcgct ggctgaagac agtaacggta cgaaaggtta tgtttttgtt
    21061 ggtgaatcgt tggactatct attgaccacc ggcggcgatg aggtggttaa catgctgaac
    21121 gatccggcaa tccatggtga aagaatcacc gtttctgata acgcgaaatt tattttaagc
    21181 agcagtaata agaatttctc tggtgctatt acgctctatt acgactggaa caacgaagaa
    21241 gataaggcac tggcaacaca atatggtttt atttgtgata cccggcgttg tacatggatg
    21301 ctggacggtt tgaaaggctc aatccaccag aaaaataaaa aagcggatta ctcaaacgtg
    21361 atggttttcc atcaaccctt tacggtggga ttttatgagt acaaagcaac agatggcgtc
    21421 ccgcgcggcc tcgttaatgc gctgctgcca gtcactctta cgctggatat agtaacgtca
    21481 ccactccagt tcctgatttt atgcacgacc agaaattgtt aatcgctgcg ggcaaacgca
    21541 ttcatgccgt ttgcccgttc actgattaat tcagcacata cttctcaata gcaaatgcca
    21601 cgccatcttc aaggttagat ttggtgacaa agttcgccac ttctttcacc gaaggaatag
    21661 cgttatccat cgccacaccg acgcctgcat attcaatcat tgcgatgtcg ttttcctgat
    21721 cgccaatcgc catgatttct tccggtttaa tacctaacac gtcggccagt gatttcacac
    21781 ccgtaccttt gttaacgcgt ttatcgagga tttcgaggaa gtacggcgca cttttcagca
    21841 cggtgtattt ttctttcact tcctgcggaa tacgcgcaat ggcctggtcg aggatggcgg
    21901 gttcatcaat catcatcact ttcaggaact gggtattggg gtccattttc tccgcttcgc
    21961 agaacaccag cggaatggtg gcaacgaaag attcatgcac cgtgtagtag ctgatatctc
    22021 ggttggcggt gtacagcgtg gtgcggtcca gggcgtggaa atgagaaccg acttcgcgag
    22081 agagtttttc caggaaacgg tagtcgtcat agctgagagc ggtttgcgcc acggtgctac
    22141 catcagcggc cttctgtacc agcgcgccgt tataagtaat gcagtagtcg cccggctgtt
    22201 ccatatgcag ctctttcagg taattgtgaa cacctgcata agggcgaccc gtcgttagca
    22261 cgacattcac gccacgggcg cgagctgcgg caatcgcatt tttaacggcg ggtgaaatgg
    22321 tgtgatcggg cagcagaagg gtgccatcca tatcgatagc aatgagtttg atagccatga
    22381 gttccccagg tagattggtt cctgacccat gctaacgcga ttccgctcaa aaatcagtac
    22441 aacacccgag ggaaaagggg atgcaacgcg cattgcgtgc tccccatttg cttagcggaa
    22501 gagtttccct ttcagcagtt ccatacctgc ggaaagcaga tcgttattgg cttgtggtga
    22561 cacttcacct tgcggtgaga gtgcatcaat aatcttcggc aattgttctg ccagtaaact
    22621 ggaagctgta ctggtatcca cgccaagttt ttgcccgaga tcggacaccg catttgtgcc
    22681 gagcgccgat tccacttgct cgccgctaac tgattgattg ctctgttgat tactcagcca
    22741 ggttgagaga atggccccta agccgccact ttgcagtttt tccagcagca cctgaatgcc
    22801 gccctgctcc tcaacccagc tcaaaatcgc ctgatatttc cccgcatcgc ctttcagaaa
    22861 ggcaccgaca acttcatcaa aaagccccat gataatcacc tgtaaagcgt tacgtgttga
    22921 cccaaaaagt atagatctgc gggatgataa ttgcggattg caggaataaa aagggcggag
    22981 atgatctccg cccggactga cgactaagtc attttatcag caacaaaaag ccattaaata
    23041 tcgatattcg ccgctttcag agcgttctct tcgataaacg cacggcgcgg ttcaacggcg
    23101 tcgcccataa gcgtagtgaa caactggtcg gcagcaatcg catctttaac ggtaacgcgc
    23161 agcatacgac ggctttccgg gtccatggtg gtttcccaca gctgttccgg gttcatctcg
    23221 cccagacctt tataacgctg gatggagagg ccgcgacggg actctttcac cagccagtcc
    23281 agcgcctgct cgaagctggc taccggctga cgacgttcgc cacgttcgat aaatgcatct
    23341 tcttccagca agccacgcag tttctcaccc agcgtgcaga tacgacgata ttcgccgcca
    23401 gtgataaatt cgtgatccag cggatagtca gtatccacac cgtgggtacg cacgcgaaca
    23461 atcggctcga acaggttttg ttcggcattg gtatggacat caaacttcca ctggctgccg
    23521 tgctgttctt tatcgttcag ttcgctgacc agcgcgttca cccagcgggt aacggtttgc
    23581 tcgtcagaaa ggtcggtttc cgtcagcgtc ggctgataga taagctcttt cagcattgct
    23641 ttcggataac gacgctccat gcggttgatc attttctgcg tcgcgttgta ctcagacacc
    23701 agtttctcta acgcttcgcc agccagcgcc ggtgcactgg cgttggtgtg cagcgttgcg
    23761 ccatccagcg cgatagagat ctggtactga tccatcgctt cgtcgtcttt aatgtactgt
    23821 tcctgcttac ctttcttcac tttgtacagc ggcggctgag cgatgtagac gtgaccacgt
    23881 tcaacgattt ccggcatctg acgatagaag aaggtcaaca gcagcgtacg aatgtgcgag
    23941 ccgtcgacgt ccgcatcggt catgatgatg atgctgtgat aacgcagttt gtccgggttg
    24001 tactcgtcac gaccgatacc acaaccaagc gcggtgataa gcgtcgccac ttcctgagaa
    24061 gagagcatct tatcgaagcg cgctttctcg acgttgagga ttttaccctt cagcggcaga
    24121 atcgcctggt tcttgcggtt acgcccctgc ttcgcagagc cgcccgcgga gtccccttcc
    24181 actaggtata gttcggaaag cgctgggtcg cgttcctggc agtctgccag tttgcccggc
    24241 aggcccgcta agtcgagcgc acctttacgg cgagtcattt cacgcgcgcg acgcgccgct
    24301 tcacgggcac gggcagcatc gataattttg ccaaccacga ttttcgcgtc ggttgggttt
    24361 tccagcaggt attccgccag cagttcgttc atctgctgtt caaccgccga tttcacctca
    24421 gaagaaacca gtttgtcttt ggtctgtgag gagaatttcg ggtccggcac tttcacggaa
    24481 acgaccgcaa tcaggccttc acgcgcatcg tcaccggtgg cgctgacttt ggcttttttg
    24541 ctgtagcctt ctttgtccat gtaggcgttc agagtacggg tcatcgccgc acggaaacct
    24601 gccaggtgag taccgccgtc acgctgcgga atgttgttgg taaagcagta gatgttttcc
    24661 tggaagccat cgttccactg caacgccact tcgacgccaa taccgtcttt ttcggtggaa
    24721 aagtagaaga tattcgggtg gatcggcgtt ttgttcttgt tcagatattc aacgaacgcc
    24781 ttgatgccgc cttcatagtg gaagtggtct tctttgccgt cgcgcttatc gcgcagacga
    24841 atggaaacgc cggagttgag gaacgacaac tcacgcagac gtttcgccag aatttcatat
    24901 tcgaactcgg tcacattggt gaaggtttca aggcttggcc agaaacgcac catggtgccg
    24961 gttttttcag tctcgccggt aaccgccagc ggggcctgcg gtacaccgtg ttcgtagatc
    25021 tgacggtgaa ttttaccctc gcgctggata accagctcca gtttttgcga cagggcgttt
    25081 actaccgaaa caccaacgcc gtgcagaccg ccggacactt tataggagtt atcgtcaaat
    25141 ttaccgcctg cgtgcagaac ggtcatgatc acttccgccg ccgatacgcc ctcttccggg
    25201 tgaataccgg tcggaatgcc gcgcccgtca tcctgtacag agacagagtt atcggcgtga
    25261 atggtgacga taatttcttt acagtgaccc gcgagcgctt cgtcgatagc gttatctacc
    25321 acctcgaata ccatgtggtg cagaccggtg ccgtcatccg tgtcgccgat atacataccc
    25381 gggcgcttac gcaccgcatc cagccctttc aggactttga tactggagga gtcataagaa
    25441 ttcgacatca acgtttctcg ctcatttatt cttgggttaa tccgttattt tacccttttc
    25501 cacggtaaac atcttcgaat tttcgtccga catgtctatt acgtgttcag cactgatcgc
    25561 gctgacaaag acctgtgatt gcgtcgcttt taagcggctg gcaagcagcc cgcgacgctc
    25621 atcatcaagc tcagaggcaa aatcatctat caggtagaga caccgccgcc cgctttcacg
    25681 ggtgaggaac tctccttgcg ccagacgtaa ggcgcacatc aacagcttaa gctgtccacg
    25741 cgataaggta tcttccaccg gcgcaccgtc ggcgcgaatg cgtaagtccg ctttatgcgg
    25801 gccgtgcgcg gtgtaggtta actggcgatc gcgttcaaaa ttacgttcca gcacctcagc
    25861 gtactctgtc tctttctccc agccgcgctg gaaagagaaa gtcagagaaa actcagggag
    25921 aaattgctta caggtatcag ccatatcggc tgcgataccg gcgctatact ccgcgcgcca
    25981 ggtgctgatt tgctccgcca gcgggatcag ttctttatcc cacgggcgta gctgttcgta
    26041 acgagtcacc tggcgcagcg ccgcattgcg ctgcttgagc aatcgcttga gattgctcca
    26101 ggcggtgaaa aatccgggtt cgttgtgaaa gcatccccag tcgaggaatg ctcttctgta
    26161 tttggggccg ccattgagta aagtaaaccc ttctggcgtt atcagctgca ttggcatcag
    26221 gtgcgccagc tccgcgactt tatgcccgtc tgtaccgtca atacggactt tgctgtcgcc
    26281 ttgtttgtct ttggttaaac caatcgccgt ctcacgctct tcgccctgta atcgtccgtg
    26341 gagaacaaac gcctcctgct cgtggcgaat gacgcgacca atctgcaaac tgcgaaacgc
    26401 ccgaccgtgg ccgagcgtat agatggcttc cagcacgctg gttttgccac tgccgttggc
    26461 acctaccaga aagttaaagc cgggagataa ggcgagatcc gcggtttcaa tgttgcggaa
    26521 atcgcggatc aacaagcggg tgagggacat tacagtctca ttggcatgac aacataagcc
    26581 gcgctctggc tggccgcatc ttcaatctgc acgctggaaa ccgaatcggt cagcatcatg
    26641 cggacgtttt cgcatttcag tgcgttcaga acatccagca catagctgac gttgaagccg
    26701 atttccatct ccgcaccgct ataggtaacg tcgaggatct cttccgcttc ttcctgttct
    26761 gggttgttgg cggtgatttt cagctggttt tcgctgacat acagacgcac gccgcggaat
    26821 ttctcgttag agagaattgc cgcacgggca aacgcctgct tgagcagatc acagccagct
    26881 tccagatgct tgtccgggtt cttcggcaga acgcgacggt aatccgggaa gcgaccatcc
    26941 accagtttcg aggtgaagat aaagtcgcca acgtgggcgc gaatgttgtt gctgccaatc
    27001 tgcacgcgca gcggattgtc gccgccgtcg agcatacgca tcagttcaat tacgccttta
    27061 cgcggcacga tcaccgaatg gcttggcaaa gattgaccaa ttggcattga acagactgcc
    27121 agacggtggc cgtcggtcgc cacggtgcgc agttcttcac cttcggtttc aaacagcata
    27181 ccgtttaagt aatagcgaac gtcctgatgt gccatagaaa actgggtcgc ttcaatcaga
    27241 cgcttcatcg tcgcctgcgg cagggtaaat tcgacttcgc tctgccagtc atcgaggttc
    27301 gggaaatctg ccgctggcag ggtagacagc gaaaaacggc tacgcccgga gcgcaccagc
    27361 atccgctcac cttccagctg cacggcaatt tccgcgcctt caggcagacc acggcagata
    27421 tcaaagaatt tgcgcgccgg aacggtcgtc gcccctggtt cgtgcggctg aaccagcgca
    27481 acgcgtgcca ccatttccat ctcgagatca gtaccggtca gcgacaacgt accgtcagca
    27541 acctgtaaca gcagattacc gagaatcggt agcgtaggac gaccacctaa cggaccgctc
    27601 acctgttgta gcggttttaa taaatgctca cgttctacgg taaatttcat aggtttacga
    27661 tgacaatgtt ctgattaaat tagaaaaatc ttctttgata tcgtggctct cttcacgcaa
    27721 ctgctcgatc ttccggcagg catgaagcac cgtcgtgtgg tcacgaccac caaaggcatc
    27781 gccaatctcc ggcagactgt ggttagtcag ctctttcgcc agcgccatcg ccatctggcg
    27841 cggacgggcc accgagcggg atcgacgctt ggaaaggaga tccgcgactt tgatcttgta
    27901 gtactccgcc accgtcttct gaatattgtc gatggtgacc agtttttcct gcaatgccag
    27961 caagtcgcgc agcgcctcac gcacgaagtc gatggtgatc gcccgtccgg taaagttggc
    28021 gttggcaatg acgcggttca gcgcgccttc caactcacgt acgttagatc gtagacgctt
    28081 ggcgataaag aacgccactt cgcccggcaa acgaatgtcg ttttcgtcgg cctttttcat
    28141 caggatcgcc acgcgggttt ccagctctgg cggttcgatc gccacagtca gtccccagcc
    28201 gaagcgggat ttcaaacgat cctcaacgcc gttgatctct ttcggatagc gatcggaggt
    28261 gagaatgatc tgttgattac cttccagcag ggcgttgaag gtgtggaaaa actcttcctg
    28321 agatcgttct ttattagcaa aaaactgaat atcgtcgatc agcagtgcat ctacggaacg
    28381 gtagtagcgt ttaaactctt cgatcgcgtt gttttgcagg gctttaacca tgtcctgaac
    28441 aaagcgctcg gagtgcatat aaaccacttt ggcattcggc ttgcgcgcca taatgccgtt
    28501 acccaccgca tgcagcaggt gagttttacc caaacccgtg ccgccataaa ggaacaacgg
    28561 gttataagca ccgccagggt tatctgccac ctggcgagcc gccgcgcgcg ccagttggtt
    28621 agatttacct tcaacgaagt tatcaaacgt gtgtttgacg tttacgttag aacgataggt
    28681 cggttctgcc ggagccggga cgttatccca acccgagcgc gtagaaggcg cagcacgttg
    28741 cggctgcgtt tgcgccacct gtgcaggggc cgcgacgttg ctcgtcactg ccgcttgtgg
    28801 cgtttgcgtc accggtttgg tgccgacttc aaaacgcagc tgtggggcat ccgctccgca
    28861 gaaactggtt agcagtccat tgatattatt aaggtacttg tcccgtaccc aatcgaggac
    28921 aaaacggttt ggcgcgtaca gggccagcgt gttatcgctc agttccgcct gcaatgggcg
    28981 tatccacata ctgaattctg tggctggtaa ctcatcctgc aatcgggcaa gacactgctg
    29041 ccaaagcgaa agtgacacgg cggactccac tcgaacaaaa gtcgataatg actaaggctg
    29101 aaacattcat gattgttgac gtacgtcgaa aagaccctgc atgagggtga cgcacgaacc
    29161 gctgtctgcg gttatatgcc cgatcaagat cctgcaaaac gatcgggacc gcggatcata
    29221 gcctaaactg cgcaagagat cttctgtttc tcacagattt tcccgattta tccacaggat
    29281 gatccagaac tcgctaagtg taaacgatcc tgccgcaggc cgggcacgat ttacgccgca
    29341 tattggaaaa tttaatgacc atagacaaaa aatggcttaa tcgatctaat aaagatccag
    29401 gacgatcctt gcgctttacc cgtcagcccg tataatcctc cacccggcgc gccatgctgg
    29461 ttttcactgg tgtgaggccg tacgttttcc ccgcgaaaag gtgcggaaaa gcgcggtaaa
    29521 taaggaaaga gaattgactc cggagtgtac aattattaca atccggcctc tttaatcacc
    29581 catggcttcg gtgtccatcg tttcattttt cggcggatat ccaataaagc cattgaattt
    29641 attcaagttt aggtagaaat cgccatgaaa cgcacttttc aaccgtctgt actgaagcgc
    29701 aaccgttctc acggcttccg tgctcgtatg gctactaaaa atggtcgtca ggttctggca
    29761 cgtcgtcgtg ctaaaggccg cgctcgtctg accgtttcta agtaataaag ctaacccctg
    29821 agtggttaag ctcgcatttc ccagggagtt acgcttgtta actcccagtc aattcacatt
    29881 cgtcttccag cagccacaac gggctggcac gccgcaaatt actattctcg gccgcctgaa
    29941 ttcgctgggg catccccgta tcggtcttac agtcgccaag aaaaacgttc gacgcgccca
    30001 tgaacgcaat cggattaaac gtctgacgcg tgaaagcttc cgtctgcgcc aacatgaact
    30061 cccggctatg gatttcgtgg tggtggcgaa aaaaggggtt gccgacctcg ataaccgtgc
    30121 tctctcggaa gcgttggaaa aattatggcg ccgccactgt cgcctggctc gcgggtcctg
    30181 atagccctca ttcgggtcta tcaacgcctg attagtccgc tactcgggcc gcattgtcgt
    30241 ttcactccaa cctgttcaag ctacggaatt gaggcattgc gcaggtttgg agtgataaaa
    30301 ggcagttggt tgacggtgaa acgcgtatta aaatgccacc ctttacaccc tggtggtgac
    30361 gatcccgtcc cgcccggacc atttgatacc agagaacact aacgatggat tcgcaacgca
    30421 atcttttagt catcgctttg ctgttcgtgt ctttcatgat ctggcaagcc tgggagcagg
    30481 ataaaaaccc gcaacctcag gcccaacaga ccacgcagac aacgaccacc gcagcgggta
    30541 gcgccgccga ccagggcgta ccggccagtg gccaggggaa actgatctcg gttaagaccg
    30601 acgtgcttga tctgaccatc aacacccgtg gtggtgatgt tgagcaggcc ctgctgccgg
    30661 cttacccgaa agagctgaac tctacccagc cgttccagct gctggaaact tcaccgcagt
    30721 ttatttatca ggcacagagc ggtctgaccg gtcgtgatgg cccggataac ccggctaacg
    30781 gcccgcgtcc gctatataac gttgaaaaag acgcttatgt gctggctgaa ggtcaaaacg
    30841 aactgcaggt gccgatgacg tataccgacg cggcaggcaa cacgtttacc aaaacgtttg
    30901 tcctgaaacg tggtgattac gctgtcaacg tcaactacaa cgtgcagaac gctggcgaga
    30961 aaccgctgga aatctccacc tttggtcagt tgaagcaatc catcactctg ccaccgcatc
    31021 tcgataccgg aagcagcaac ttcgcactgc acaccttccg tggtgcggcg tactccacgc
    31081 ctgacgagaa gtacgagaaa tacaaattcg ataccattgc cgataacgaa aacctgaaca
    31141 tctcttcgaa aggtggttgg gtggcaatgc tgcaacagta tttcgcgacg gcgtggatcc
    31201 cgcataacga cggtaccaac aacttctaca ccgctaatct gggtaacggc atcgccgcta
    31261 tcggctataa atctcagccg gtactggttc agcctggtca gactggcgcg atgaacagca
    31321 ccctgtgggt tggcccggaa attcaggaca aaatggcagc tgttgctccg cacctggatc
    31381 tgaccgttga ttacggttgg ttgtggttca tctctcagcc actgttcaaa ctgctgaaat
    31441 ggatccatag ctttgtgggt aactggggct tctccattat catcatcacc tttatcgttc
    31501 gtggcatcat gtacccgctg accaaagcgc agtacacctc catggcgaag atgcgtatgc
    31561 tgcagccgaa gattcaggca atgcgtgagc gtctgggcga tgacaaacag cgcataagcc
    31621 aggaaatgat ggcgctgtac aaagctgaga aggttaaccc gctgggcggc tgcttcccgc
    31681 tgctgatcca gatgccaatc ttcctggcgt tgtactacat gctgatgggt tccgttgaac
    31741 tacgtcaggc accgtttgca ctgtggatcc acgacctgtc tgcacaggac ccgtactaca
    31801 tcctgccgat cctgatgggc gtaacgatgt tcttcattca gaagatgtcg ccgaccactg
    31861 tgaccgaccc gatgcagcag aagatcatga cctttatgcc ggtcatcttc actgtgttct
    31921 tcctgtggtt cccgtcaggt ctggtgctgt actatatcgt cagcaacctg gtaaccatta
    31981 ttcagcagca gctgatttac cgtggtctgg aaaaacgtgg cttgcatagc cgcgagaaga
    32041 aaaaatcctg attcggtgag ttttcgctaa aataagggcg gtcagttgac cgcctttttt
    32101 cttttcgtag ggcggataag caccacacat ccgccacaca aagcaacagg aacatcatga
    32161 gcgataatga cactatcgta gcccaggcca cgcctccggg acgtggcggc gttggcatcc
    32221 tgcgcatctc cggcctcaaa gcccgtgaag ttgccgaaac cgtgctgggt aaactgccta
    32281 agccacgcta cgccgattat cttccgttta aagacgccga tggcagcgtg ctcgatcagg
    32341 ggattgcgct atggttccct ggcccgaact cgttcaccgg cgaagatgtg ctggaactgc
    32401 aaggtcatgg cggtccggtg atcctcgacc tgctgttaaa acgcattctg accattcccg
    32461 gcctgcggat tgcccgccct ggtgagtttt ccgaacgcgc atttctgaac gataaactcg
    32521 acttagccca ggccgaggcg attgcggatc ttatcgacgc cagctcggaa caggcggccc
    32581 gttcggcgct aaactcgctg caaggcgcgt tctccgcacg ggtcaaccat ctggtggaag
    32641 ccctcaccca cttgcgcatt tacgtcgaag cggcaattga tttcccggat gaagagatcg
    32701 atttcctctc cgacggcaaa attgaagccc agctcaatga cgtaattgcc gatctcgacg
    32761 cggtacgcgc cgaagctcgt cagggtagtt tgttgcgcga agggatgaaa gtggtgattg
    32821 ccggacgtcc taacgccggt aaatcgagcc tgctgaacgc gctggcgggc cgtgaagcag
    32881 caatcgtaac cgatatcgcc ggaaccacgc gtgacgtgct gcgtgagcat atccacattg
    32941 acggaatgcc gttgcatatc atcgataccg ccgggctacg tgaagccagt gacgaagttg
    33001 aacgtattgg tatcgagcgc gcatggcagg aaattgaaca ggcagaccgc gtgctgttta
    33061 tggtcgatgg caccacgaca gacgccgttg atccggcaga gatctggccg gaatttatcg
    33121 cccgtctgcc agcgaaactg ccgatcaccg tggtgcgcaa taaagccgat atcaccggcg
    33181 aaacgttggg gatgagcgaa gtgaacggtc acgcgttaat tcgtctttcg gcgcggactg
    33241 gcgaaggcgt ggatgtgctg cgtaaccatc tcaaacagag catgggcttt gacactaata
    33301 tggaaggcgg cttcctggcg cgtcgtcgtc acctacaggc gctggaacag gcggcagagc
    33361 atttgcagca aggtaaagcg caactgttag gtgcctgggc gggtgaactg ctggcggaag
    33421 agttgcgcct ggcgcagcag aacttaagcg agatcaccgg ggagtttact tcagacgacc
    33481 tactggggcg gattttctcc agcttctgta tcggtaagta accgcgcttg cgaagccgca
    33541 ttctgactgt cagatgcggc ttcgcttcat tgttagcact cctgttattc ctcaaccctt
    33601 ttttaaacat taaaattctt acgtaattta taatctttaa aatagatatt taatattgcg
    33661 tcccgaacga ttgtgattcg attcacattt aaacaatttc agaatagaca aatttcttga
    33721 gtattatact gtagcctcgt gtctttcgag gataagtgca ttatgaatat cttacatata
    33781 tgtgtgacct caaaatggtt taatattgac aacaagattg tcgatcaccg cccttgattt
    33841 gcccttctgt agccatcacc agagccaaac cgattagatt caatgtgatc gattagtttg
    33901 ctatatctta attttgcctt ttacaaaggc catctctcgt ttatttactt gttttagtaa
    33961 atgatggtgc ttgcatatat atctggcgaa ttaatggata ttgcaaatgt aatattcaca
    34021 gggatcactg taattaaaat aaatgaagga ttatgtaatg gaaaacttta aacatctccc
    34081 tgaaccgttc cgcattcgtg ttattgagcc agtaaaacgt accactcgcg cttatcgtga
    34141 agaggcaatt attaaatccg gtatgaaccc gttcctgctg gatagcgaag atgtgtttat
    34201 cgatttactg accgacagcg gcaccggggc ggtgacgcag agtatgcagg ccgcgatgat
    34261 gcgtggcgac gaagcctaca gcggcagccg cagctactac gcgttagccg agtcagtgaa
    34321 aaatatcttt ggttatcaat acactattcc gactcaccag ggccgtggtg cagagcaaat
    34381 ctatattccg gtactgatta aaaaacgcga gcaggaaaaa ggcctggatc gcagcaaaat
    34441 ggtggcgttc tctaactatt tctttgatac cacgcagggc catagccaga ttaacggctg
    34501 taccgtgcgt aacgtctata tcaaagaagc cttcgatact ggcgtgcgtt acgactttaa
    34561 aggcaacttt gaccttgagg gattagaacg cggtattgaa gaagttggcc cgaataacgt
    34621 gccgtatatt gttgcaacca tcaccagtaa ctccgcaggt ggtcagccgg tttcactggc
    34681 aaacttaaaa gcgatgtaca gcatcgcgaa gaaatacgat attccggtgg tcatggactc
    34741 cgcacgcttt gccgaaaacg cctatttcat caagcagcgt gaagcagaat acaaagactg
    34801 gaccatcgag cagatcaccc gcgaaaccta caaatatgcc gatatgctgg cgatgtccgc
    34861 caagaaagat gcgatggtgc cgatgggcgg cctgctgtgc atgaaagaca acagcttctt
    34921 tgatgtgtat accgaatgca gaaccctttg cgtggtgcag gaaggcttcc cgacatatgg
    34981 cggcctggaa ggcggcgcta tggagcgtct ggcggtaggt ctgtatgacg gcatgaatct
    35041 ggactggctg gcttatcgta tcgcgcaggt gcagtatctg gtcgatggtc tggaagagat
    35101 tggcgttgtc tgtcagcagg cgggcggtca cgcggcattc gttgatgcag gtaaactgtt
    35161 gccgcatatc ccggcagatc agttcccggc acaggcgctg gcctgcgagc tgtataaagt
    35221 cgccggtatc cgtgcggtag aaattggctc tttcctgtta ggccgcgatc cgaaaaccgg
    35281 taaacaactg ccatgcccgg ctgaactgct gcgtttaacc attccgcgcg caacatatac
    35341 tcaaacacat atggacttca ttattgaagc ctttaaacat gtgaaagaga acgcggcgaa
    35401 tattaaaggg ttaaccttta cctacgaacc gaaagtattg cgtcacttca ccgcaaaact
    35461 gaaagaagtt taattaaaac actcagagtg gctataagga tgttagccac tctattaccc
    35521 tacatcctca ataacaaaaa tagccttcct ctaaaggtgg catcatgact gatcaatcag
    35581 aaaaaaaaca ctctgcattt tggggtgtta tggttatagc cggtacagta attggcggtg
    35641 ggatgtttgc tttacctgtt gaccttgccg gagcctggtt tttttggggc gcttttattc
    35701 ttattatcgc ctggttttca atgttacatt cagggctatt attattagaa gcaaacttaa
    35761 attatcccgt cggttccagt tttaacacca tcaccaaaga tttaatcggt aacacctgga
    35821 acataatcag cggtattacc gttgccttcg ttctctatat cctcacttat gcctatatct
    35881 ctgctaatgg tgcgatcatt agtgaaacga tatcaatgaa tttgggctat cacgctaatc
    35941 cacgtattgt cgggatctgc actgccattt tcgttgccag cgtattgtgg ataagttcat
    36001 tagccgccag tcgtattacc tcattgttcc ttgggctgaa gattatctcc tttgtaattg
    36061 tttttggttc tttcttcttc caggtcgatt actccattct gcgcgattcc accagcacca
    36121 ctgcggggac gtcttacttc ccgtatatct ttatggcttt gccggtgtgt ctggcgtcat
    36181 ttggtttcca cggcaatatt cccagcctga ttatttgcta tggcaaacgc aaagataagc
    36241 tcatcaaaag cgtggtcttc ggttcgctgc tggcgctggt gatttatctc ttctggctct
    36301 attgcacgat ggggaatatc ccgcgagaaa gctttaaggc gataatctcc tcaggcggca
    36361 acgttgattc gctggtgaaa tcgttcctcg gcaccaaaca gcacggcatt atcgaatttt
    36421 gcctgctggt gttctctaac ttagctgttg ccagctcgtt ttttggtgtc acgctgggat
    36481 tgttcgatta tctggcggat ctgtttaaga ttgataactc ccacgccggg cgtttcaaaa
    36541 ccgtgctgtt aaccttcctg ccacccgcgt tgttgtatct gatcttcccg aacggcttta
    36601 tttacgggat cggcggtgcc ggactgtgcg ccaccatctg ggcggtaata attcctgctg
    36661 tactggcaat caaagcccgc aagaagtttc ccaatcagat gttcacggtc tggggcggca
    36721 atcttattcc ggcgattgtc attctctttg gcataaccgt aattttatgc tggttcggta
    36781 acgtctttaa cgtgttacct aaatttggct aaatctttca ggaagccagc cattcgctgg
    36841 cttcttgcct gtcaggaaat ctcttttgtc caaatggcaa ctcgcctgat tatccttcac
    36901 cacgtatgct ttgcgtcacc ttactatcag gacgctttag cccatgtccc gctttttgat
    36961 ttgtagtttt gccctggttt tactttatcc cgcagggatt gatatgtacc tcgttggttt
    37021 accgcgcatc gccgccgatc tcaatgccag cgaagcgcag ttgcatattg cgttctccgt
    37081 ttatctggcg gggatggcgg ctgcgatgtt atttgccggt aaagtggccg atcgttcagg
    37141 gagaaagcct gtcgccatac ccggcgcggc gctatttatt atcgcctcgg tgttctgttc
    37201 actggctgaa accagcgcgt tatttcttgc agggcgattt ctacagggac tgggcgcggg
    37261 ctgttgttac gtagtggcgt tcgccatttt gcgcgacacg ctggatgatc gacgtcgggc
    37321 taaagtgctg tcgttactca acggcattac ctgcatcatt ccggtgttag cgccggtgct
    37381 cggacacctg attatgctta aattcccttg gcagagtctg ttctggacga tggcaacgat
    37441 gggcatcgcg gtactgatgt tgtctttgtt tattttaaaa gaaacgcgcc ctgcggcccc
    37501 cgcagcttcg gacaaaccac gagaaaatag cgagtcactg cttaaccggt ttttcctcag
    37561 ccgtgttgtt atcaccaccc tcagcgtttc ggtgatcctc accttcgtca acacgtcgcc
    37621 agtattgctg atggaaatca tgggttttga gcgcggagaa tacgccacca ttatggcgtt
    37681 gaccgctggc gtcagcatga ccgtttcatt ctccacgccg tttgcgctgg gaatttttaa
    37741 gccacgtacg ttgatgatca cctcacaggt gttattcctg gcggcgggga tcacccttgc
    37801 cgtttcacct tcccatgcgg tttcgctgtt tggtatcacg ctgatttgcg ccggtttctc
    37861 ggtaggtttt ggcgtagcga tgagtcaggc gttggggccg ttttcattac gcgcgggcgt
    37921 agccagctcg accttaggta ttgcgcaagt ttgcggttcg tcactgtgga tttggctggc
    37981 ggcggtggtt ggtatcggtg catggaatat gctgatcggg attctgattg cctgtagcat
    38041 agtgagcctg ttgctgatta tgttcgtcgc gcctggacgc ccggttgccg ctcatgaaga
    38101 aatccatcac aacgcttgat ctcaatctgc tgctctgtct gcaactgctg atgcaggagc
    38161 gcagcgtgac caaagcggcg aagcggatga acgtgacccc ttcgtcggtg agtaagtcgc
    38221 tggcaaagtt aagagcgtgg tttgacgacc cgctctttgt gaactcaccg ctggggctgt
    38281 cgcccacacc gctaatggtc agcatggagc aaaatctggc ggagtggatg caaatgagca
    38341 atcagttgct ggacaaacca ctccacgaaa cgccgcgcgg tcttaagttc gaactggcgg
    38401 cggaatcgcc gctgatgatg atcatgctta atgcgctgtc gaaacggatc taccaacgat
    38461 acccgcaggc gaccatcaaa ttacgtaact gggattacga ttccttagat gccattactc
    38521 gtggtgaagt ggatattggt ttttccggtc gcgaaagtca tccccgttcg cgggagctgt
    38581 taagctcgct accgttatcc attgattatg aagtgctgtt tagtgatgtg ccctgcgtct
    38641 ggttacgcaa agatcatccg gcactgcatg aagcatggaa tctggacacc tttttacgtt
    38701 atccgcatat cagcatttgc tgggaacaga gcgatacctg ggcgctggac aatgtgttac
    38761 aggagctggg gcgcgaacgc acgattgcta tgagcctgcc ggaattcgag cagtcactgt
    38821 ttatggcagc acagcccgac aatctgctac tggcgaccgc gccgcgctac tgccagtact
    38881 acaatcaact ccaccaactg ccgttggttg ctcttcctct cccgtttgat gaaagccagc
    38941 aaaaaaagct ggaagtccct tttacccttc tgtggcataa acggaacagc cgtaatccga
    39001 agatcgtctg gttacgggaa accattaaaa atctttacgc gtcgatggca taaccgaatc
    39061 gtatgaaacg cgacccaatt tcacaatgaa atgtaaaaaa gttgtaataa atttatctga
    39121 atcgaacttt tagccgcttt agtctgtcca tcattccagt aaatgattac tcttgtattc
    39181 ataatggacc attaagcatg gagcgaaaaa tggcgactca ctttgcccga gggattttaa
    39241 cggaaggaca tctgatttct gttcgtctcc cctcccagtg tcatcaagaa gcccgaaaca
    39301 ttccccctca tcgtcaaagc cgttttctgg cgtccagagg tttactcgca gaactgatgt
    39361 tcatgctgta tggcattggc gaattgccgg aaatcgtcac cctgccgaaa ggaaaaccgg
    39421 ttttcagcga taaaaatttg ccttcgtttt ctatttccta tgccgggaat atggtcggcg
    39481 tggcgttaac aaccgaaggt gaatgtggcc tcgatatgga actacagcgt gcgacacgcg
    39541 ggtttcatag cccacacgcg cccgataacc acaccttttc cagcaatgaa tcgctatgga
    39601 tcagtaaaca aaacgatcct aacgaagcgc gggcgcagct catcacgctg cgccggagcg
    39661 tgctaaaact aaccggtgat gttttgaatg acgatccgcg cgatctgcaa ctactgccca
    39721 ttgccggacg cctgaaatgt gctcatgtaa atcatgtaga agcgttatgc gacgcggagg
    39781 acgtgctggt gtggtccgtg gcggtcacgc ccacgattga aaagctcagt gtctgggagt
    39841 tagatggcaa acacggctgg aaaagcctgc ccgatattca cagccgcgcc aacaatccta
    39901 ccagccggat gatgcgtttt gcccagctct ctaccgtgaa ggctttttcg ccaaattgat
    39961 agacaaccac aggagtcatc atgtctgaaa aattgcaggt ggttacgtta ctggggagcc
    40021 tgcgcaaagg ctcatttaat ggcatggttg cacgtaccct gccgaaaatt gctccggcga
    40081 gtatggaagt caatgcgttg ccttccattg ccgacattcc cctgtatgac gctgacgtac
    40141 agcaggaaga cggttttcca gcaacggttg aagctctggc ggaacagatc cgtcaggctg
    40201 acggtgtggt gatcgtcacg ccggaatata actactcggt accgggtggg ctgaaaaatg
    40261 ccatcgactg gctttcccgc ctgccggatc aaccgctggc tggtaaaccg gtattgattc
    40321 agaccagctc aatgggcgtg attggcggcg cgcgctgtca gtatcacctg cgccagattc
    40381 tggttttcct cgatgcaatg gtgatgaaca agccagaatt tatgggcggc gtgattcaga
    40441 acaaagttga tccgcaaacc ggggaagtga ttgatcaggg tacgctggac cacctgaccg
    40501 ggcaattgac cgcatttggt gagtttattc agcgagttaa gatctaaata aaaacccgcc
    40561 agcaatcatg catggcgggt ttttaacgcg ctatcgattt tagtgagcgt cgataaagac
    40621 aatcttcagg ataaacagca gcgcaacgat gattacgcac gggctaaggt cacgcagacg
    40681 tccggtacca atcttcatca cgcagtagga gataaagccc agcgcgatac cttcagtaat
    40741 cgagaagctg aacggcatca tcacagcggt aataaacgcc ggaacagatt cagtaagatc
    40801 ctgccagttc acgcgagcaa gacttgaggt catcaacacg ccaacgtaaa tcagcgcacc
    40861 agctgcagcg tagcctggca ccatccccgc cagcggcgac aggaagataa ccagcaggaa
    40921 cagcagacca acaaccactg ccgtcagacc ggtacgaccg ccaacggaaa cgccggaaga
    40981 agattcaata tacgccgtaa cagaagaagt accgataaac gaaccggtca ccgaagagat
    41041 actgtcgaca tacagcgcct gcttcatgcg cgggaattta cctttctcat cagccagacc
    41101 tgctttatcg gtcacgccaa tcagcgtacc ggaggagtca aacaagttga ccagcatgaa
    41161 agagaaaatc acccctgcca gcccaaggtt aaacgacccg gctaaatcta catgacccac
    41221 gacactcatt acgctcggcg gcgcagaaac gatgccatta tagtggacat cacccagcat
    41281 ccagcccagc agcgttgtca ccacgatgga aaccagcacc gccgcgtgaa tattgcgcga
    41341 ggccagaatg gcgatgatga agaagccgag gatccccagc agcacgctgt gagaagtcag
    41401 attaccgatg ctcaccagcg tttccgggtt agcgacaatc acacctgcgt ttttcagccc
    41461 catcatgcca ataaacagac cgataccact ggtgatgccc acacgtagac ttaccgggat
    41521 gttggctatc atccagtagc gaacgcggaa aatcgtcagt aacagcagac caatcgcgcc
    41581 ccagaagatt gcgcccatcc cgacttgcca cggcaagccc atcgcctgta caacgacaaa
    41641 agcgaagaac gcattcaggc ccattgccgg tgccagtgca actggcaggt tagcaaacag
    41701 ccccatcata atactgccga atgcagcaat cagacaggtc gtgacgaaga cggcgctggt
    41761 atccatgcca gcaacgccaa gaatttgcgg gttaacaaaa acgatgtaaa ccatcgtcag
    41821 gaaggtggta aaaccggcga tcacttcggt ccgtgccgtc gtgccatgtt cgcgcagttt
    41881 aaacacgcgt tccagcatcc cctggccaga agcctgggtt gtgtgttgtt gactcattat
    41941 ctatttccga acaaggaggg aaaatccgtc gctatcgtat accaaaatga gacaatatgg
    42001 acggctgaag ataacttttt ttcattgtat ttgcttatac ggcaacgatt gcgtcatgcg
    42061 aattggcatg acgaaaacgt taaactaacg ataaaggaaa gacatgtccc agatagaagc
    42121 ggtatttttc gactgcgacg gtacgctggt cgatagcgag gtcatttgct ctcgcgccta
    42181 tgtcacgatg ttcagggaat ttggcattca cgttgacctg gaagagattt ttacccgttt
    42241 taaaggcgta aaactctacg aaatcatcaa catcatcagt aaagaacagg gcgtgacgat
    42301 gatccaggcc gatgccgagc acgtttaccg tgcggaagtg gcgcgcctgt ttgatagcga
    42361 gcttgaggtg attgcaggag cgaacgaatt gctggctagt gtgaaagtgc cgatgtgcgt
    42421 cgtctctaac ggcccggtca gcaagatgca gcattcgctt ggtaagctca acatgctgca
    42481 ctacttcccg gaaaaactgt tcagcggcta tgatatccag cgttggaagc ccgatccggc
    42541 attaatgttc catgcggcaa aagcgatgaa tgtgaacgtt gaaaactgca ttctggtcga
    42601 tgactccagt gccggtgcgc aatcagggat agatgccgga atggaagtgt tttacttctg
    42661 cgctgacccg cacaataaac cgatcgttca cccgaaagtc accaccttta cccatctttc
    42721 gcaattaccg gaactgtgga aggcgcgtgg ttgggatatt acggcatagt tattcacact
    42781 cccttcactt actccactta aattggcacg caaaggtaag taaagggagt ttgatatgtc
    42841 tgtttcacgt cgggtaattc atcacggact gtattttgcg gttttagggc cgttaattgg
    42901 tgttctgttt cttgtcctct acatattctt cgcaaaagaa ccgctggttc tttgggtgat
    42961 aatacatcca atttttctct tattgtcgat aactacggga gctattcctg cgttgttaac
    43021 cggtgtaatg gttgcctgtc tgccggaaaa gatcgggtca cagaaacgtt atcgttgtct
    43081 ggctggtggc ataggtggag ttgttatcac cgagatctat tgcgctgtta tcatacatat
    43141 taaggtcatg gcttcctcag tgttgtttga aaacattctt tctggtgaca gtctcgttgt
    43201 ccgcatcatt cctgcattgc tggcaggtgt ggtgatgagc agaatcatta cacgtctacc
    43261 cggactggat atttcatgtc ctgaaacaga ctctttaagt taagcgggat gttttatctt
    43321 ttggctactc aaaagcagac aggatgtttc tatgactcaa aatatcaggc cgttacccct
    43381 attcaaatat catcccaagc cactggaaac aggcgcattt gaacaggata aaaccgtaga
    43441 gtgcgattgc tgtgaacaac agacgtcagt ttattactcg ggtccctttt attgcgttga
    43501 tgaagttgaa catctctgtc cgtggtgtat tgcgaacggt tctgctgctg aaaagtttgc
    43561 aggtagtttt caggatgatg ccagcatcga aggtgttgaa tttgagtatg atgaagagga
    43621 cgattttgcc ggtattaaga acacatatcc tgatgaaatg ctgaaagagt tggttgaacg
    43681 cacgccaggt tatcatggat ggcaacagga attctggctc gcgcattgtg gcgatttctg
    43741 tgcttttatc ggctatgtgg gctggaatga tataaaagat cgcctcgatg aatttgccaa
    43801 ccttgaagaa gattgtgaga atttcggtat tagaaattct gatctagcta aatgcctgca
    43861 aaagggtggt gattgtcagg gttatctctt ccgctgtctc cactgcggca agctgagact
    43921 gtggggcgat ttttcatagt tatttatatg atgagaacag gccggcgcgt aattcacaca
    43981 tccggcctta tttttaagct taaccgagcg ctaattctgc ggcagcggct ttatcagcga
    44041 ttaccatcag cgaaggatgc agctgcaaca cggaagcagg aacatcttcg gtaaccggac
    44101 cttgcagaac atttttcagt gcctgcgctt tacccgcgcc actgacaatt atcagcaagt
    44161 ttttcgccgc catgatgctt ttcggcccca tcgtcacgta gctgtcaggc actaatgaaa
    44221 agtcgccacc caactcgcca tgcgccacaa tatcaaccat ctctccctgg atcgggaact
    44281 ccacggtttg ctcatggaaa tgggtcgtat ttggcaaatt gccacaaaaa tgaccatcta
    44341 cacctaatcc caacaccacc aaatccaggc caccttcacg cgccagtttc tgatcatgct
    44401 cgcggtagtt atcaatagtg agcttctgga tattctcttc tttgatccct gcaggggtga
    44461 aaaacagatt acgcagattg gtaatcgtta cgccttcccc ttctttgcca cgaaatggaa
    44521 tttcatcgaa attgtagaaa tagcagttat cgtaccaggg cttaccttta accagagtga
    44581 tgagatattc gtacatgcct ttgggcgtgc taccggcggt aattgccagg ttaacgcgac
    44641 gcatctttga catataacca agcagatgat gtgcggcgac acggctcatt tcctggtaat
    44701 cttcggtaat gatcaatttc atcttaatgc cttattttat ttaaataatt tctgtacaaa
    44761 ggctgcatag gctggtcgcc agacatccat ttcatggttc agaccgggat attcctggta
    44821 atcaaacttt atttttttct gctcaagctc agttttcagc ccggcgatat ccttgccggt
    44881 tacgacatct ttatcgccca cgaccacagt aaaattacgt agttgctggt taatagctgc
    44941 cggatcgttc agccgggcag cgaccccttc atctggtacg gtcgtcgtgg taacaccact
    45001 gaatgtggcc agccagccaa agctttccag atgattaatt cccgatacca gtgcctgata
    45061 cccaccttgt gaaagccctg ccagtgcgcg accatcggca tctttacgga cattaaaacg
    45121 cttgctaatc agcgggataa tatcgttcat cagttcgcga tctgccgctt tagcatttaa
    45181 cggataaaag actttacgtc tctcctgagg aacgaaatct tcgggaataa tgcccttcgc
    45241 atcggtttcg gtatccggga tcaccaccag catcggttta attttccctt cagccagcag
    45301 gttatccatg atttgcggga tacgcccctg atcaatagcg gaacgtccgg tatcaccaaa
    45361 gccgtgatag aaatagagca ctggcaaagg ctcgcctatg ccggtgtatc ctggcggggt
    45421 ccagacatac atctgacgtt cggattgcaa tgcgttggag tggtaagtta tggcgatcaa
    45481 atcaccatgc acaacagaac gtgtatccag ataactgccc ggtaccagaa tcatactgga
    45541 gttaacctga cgctgaggct tagtcattgc cgtgcctgta tcaatgctgc gtacaccatc
    45601 aacattgaaa aaatactcgt acagattgcc tttcaggaca ggcgtgcgcc acgaccagac
    45661 tcccgcttca tctttggtca tcgggtgaat attgtccgga accggaacac ccaccactac
    45721 ggagacattt tttgccccag gggcaaagta gcgaaaggtc acgctgttat cggtattgac
    45781 ctgagtcaca tactgtttca ccggaatagt gggtgccggg ctggctggca tatccgctgc
    45841 tatggcccat tgagcagaaa taccgctggc aatagccagc gttaaagcag caatttttat
    45901 attcatcgta atattccttt tattaagttc cattaccacc agatttcagc ctgggcaccg
    45961 acagcaaact ggtcgtcttt attgtcttca aaggtgaagc catccagttc gttttccaga
    46021 gctttgatat atgtagcgta gaaacgaatt tccgggcgcg aggtcaacat actggtattg
    46081 actttaaagg tatggaagag cgtggtttta taaccagact cattatattt attgctattc
    46141 gcatctttgt tttgctgggt gaaatagccc agttcaacac ctgtctggtt atattggtcc
    46201 caaatatagg ccgggcgaac aaccgcacga atagattcga aatcagaatg tgcgcctgtt
    46261 tcgtagctat aaatatcgtt accgaaggag taaacaatcg cgttagccac aatgaaatga
    46321 tcgccgatat aagcttcgcc ctgcgaagtc agacgaactg cagttccgcc tgtgtgatca
    46381 ccataataac gaccattaaa ggtagtaaat ggacttgcac cagcataacg accaaagtta
    46441 ctggcgatag agttattcgc aaccaggaag gagaattcgt tgaagccacc cttatcaaat
    46501 ttctgcgtta aagatgtacc aaacatccag gtatctttcc agtcataata cccgttatta
    46561 tcctgattat ctttttccga tgcgctttca tttgctgaga cataacgacc gctcaccatt
    46621 aaggtggctt tatcccataa cgggatatct ttatagcgta aatcaatggt attggtatta
    46681 atctgctgtt tgttttgcag gctgcgatcg taatcatcga catcttcacg aaccagcgcg
    46741 atatcaattt tacccggacc gactttccag ttttccagac ctacacctgc ggcagcatcg
    46801 gtacgctgcg ttttccagtc aagcatctgg atttcaattt tcggcgcacc gtgtttaccc
    46861 acccagaaat cagcctctgg cgcaaagggc aggaaacctt tggtggtaac gtacatatca
    46921 gagaactgca taaagttctc gccaccggcg ttatcgccaa accagccagt agagtactgc
    46981 tgacccacgt taccatccat catcacgatg gcatcaaccc gtttgccgtt ttcgttgtag
    47041 acacgttgtt ttaactgcaa atcaaaccag ccggagtatt cgttaccaaa gcggcccaga
    47101 gaaccaattg cccatgattt aggtgaacca tgggaggctg tgccccaacc agaacggtag
    47161 tagccgttgt aactaaagcc gatttcatct ttcacaaatt tactgaaatc tttcagagtc
    47221 atggaagaat aaatcgagcc tgtctcactg gcatttttct cttcattttt aaccagtaca
    47281 gcatcaggct ttgcggcacg actggtcggg aatggattgg cggcataccc ttgatcattc
    47341 gcacttacgc tacgattcac cgtcgctggc gtatactttt tcttctcttc atctttatat
    47401 tttttcagtt cgctttgcgt ttctcttaac gccttttcta atagctcaag gcgttgttcc
    47461 acggttaatg attcagccaa tgattgtgcg gaaaaggcta acggtgccat taataaaatg
    47521 gcagaggtaa taatatttcg tctaaacata atatcccttt atggtgcaaa gaaagaatta
    47581 acgcatcgca tccagactgt tctgaatgcg acgatattta aggtgcttta ttggttattt
    47641 ttttaatgat agcccccgag ttttgatcac ttctgcatac catccgaagc ttttcttgcg
    47701 cgttcttgtg aggcttcctt caccattatc atcacgatcc acataaataa agccgtagcg
    47761 cttagacatt tgtgaatgag atgcactgac taaatcaatt ggcccccaac tggtgtaccc
    47821 cataatatcc acaccatcgg caatcgcttc atttacctgt accaggtgat catttaaata
    47881 ggcaattcga taatcgtcct gtatcgaacc atccacttca acgctgtctt ttgcgcctaa
    47941 tccgttctcg acaataaata acggtttttg ataacgatcc caaagcgtat ttaacagaat
    48001 ccgtaatcca accggatcaa tttgccaccc ccactctgaa cttttcagat gcggatttgg
    48061 gatcatattc agtatgttgc cctgcgcatt tttattaatg ctttcgtcgt gggaaacaca
    48121 accggtcatg taataactaa aagagatgaa atctacggta tgttttaaat cttctgcgtc
    48181 actttcagtc atctcaatgg tgatattgtg gtcgcggaag aaacgctgca tatagccggg
    48241 atactgacca cgcgcctgaa catcaccaaa gaacatccag cgccggttct cttccatggc
    48301 ctgcaacata tcctgtggct ggcaggtgag ggggtaaacc agcccaccga gaagcatatt
    48361 gccaattttc gcttcgggga tcaggctatg acaggcttta actgcccgcg cactggcaac
    48421 cagttgatga tggatcgcct gataaacttc cgcctcgcca ctctcttctg ccagccccac
    48481 gcccgtgaat ggcgcgtgta atgacatgtt gatttcatta aatgtcagcc ataacacaac
    48541 tttatgttgg tagcgggtaa agaccgtgcg tgcgtaatgc tcgaagtgat cgatgaccgc
    48601 ccgattagcc caaccgccgt agtttttcac cagcccatat ggcatttcgt aatgggataa
    48661 cgttaccagc ggcttgatcc ccgcctgcgc catttcatca aacagccgct cgtaaaacgc
    48721 taaccccgct tcattcggtt cggcttcgtc gccctgaggg aaaattcgcg cccaggcaat
    48781 ggaaatacgc agacaggtga agcccatctc ggcaaataac gcgatatctt ccgggtaacg
    48841 gtgataaaaa tcgatggcga catctttgat attctctttc cccaggatgc gcggttccat
    48901 ttttcccatt acgccatgag gctgtaaatc tgaggtcgtg atccctttgc catcttcctg
    48961 ccatgcgcct tccacctgat tggcagctgt tgcaccaccc caaagaaatg tttctggaaa
    49021 tgctttcata attaactcct tttatcgtta gcgaatgatg gataacagcg gctcaccagc
    49081 gtttatctgc accgtgccgt ggggtaatac gtccgtaaaa tcatcgctat tactgattaa
    49141 taccggcgtc gtcagatcaa atccggcctc gcgaatagca gggatatcaa aagaaatcag
    49201 ccgatcgcct gtattgacct tgtcacccac gttgacgtga gcggaaaaga atttgccgtc
    49261 cagttttacg gtgtcgatac cgacatgaat caggatctcc acgccatcat ctgactcaat
    49321 gccaatggcg tgtaatgtgg cgaacaacga agcaattcga cccgccaccg gagaacgcac
    49381 ttcaccaaca gagggcagaa tggcaatacc tttacccaac aggccactgg caaacgtggt
    49441 atcagcgacg tgaatgagcg gcacaatatc tcccgtcatc ggtgaacaga taccgccctg
    49501 ctcaggtgta ataatctctg gtgttttctc ttgctgggca acttgcgctg gctgacgttt
    49561 agcggtgatg aaatgaagca tcaccgtacc gacaaatgcg caaccgatgg caatgacacc
    49621 accaataacg ctggcccata cggtgaaatc aatccccgtt gacgggatgg tttgcatgaa
    49681 ggtgaaaata cctggcaaac caaaggagta aactttcgtt tgcgcgtagc caatgatggt
    49741 ggcccccaat gccccactta tgcaggcgat aacgaagggg tacttacgcg gcaggttgac
    49801 gccatatact gccggttcgg tgataccaaa cagccccgtc aacgccgccg atcccgctac
    49861 cacttttttc tgcgcatcgc gttcgcagag gaagacgccg agcgccgccc cgacttgcgc
    49921 cataatggcg ggcattaaca gcgggatcat ggtgtcgtag cccagcacgg tgaagttatt
    49981 gataattaaa ggtatcaaac cccaatgcag accaaacatc acaaagattt gccagaagcc
    50041 gcccattacc gcgcctgcaa atgcaggaac cgcctgataa agccagagat aaccggcagc
    50101 aatcagttca cttatccagg ttgatagcgg ccccaccagc agaaatgtga tgggcgtgat
    50161 gaccatcaga catagcaagg gtgtgaagaa atttttgatt gccgaaggta accacgcatt
    50221 aagtcggcgt tccagaatgc tgcacaacca ggcagaaaaa ataatgggaa taaccgatga
    50281 cgagtaattc aacaatgtga ccggaatacc caggaaatcc aggcccagcg catccacttt
    50341 ttgcccgttc tcgaaggcag tcagaattaa tggatgcact aacgctccgc caatcaccat
    50401 ggcagtaaat ggattgccgc tgaagcgttt ccctgcggtg tagcccagga ttatcgggaa
    50461 gaaccaaaac aaggcatcac tggcgctaaa taaaattaaa taagtaccac tttgttcggt
    50521 cgtccactga aaagtgagtg ccagagccaa catacctttc aggatcccgg ttgccgccat
    50581 caaaccgatc agaggcgtaa aaatacctga aataacataa acaaagcggt ttaacagatt
    50641 acctttatca tcattttccg gtgcctgttg cgctttttcg ccaaggcctg ccacgctgtt
    50701 aaccgccagg aagacatcgg ccacatggtt acctatgaca acctgaaact ggccaccgct
    50761 ttccaccacc ataataatac cgggggtctt tttcagtacc tcagcttgcg ctttgctttc
    50821 atcctttaac ttaaaacgta atcgcgttgc acaatgcatc agactcacaa tgttatctgc
    50881 gcccccgact cctgcgacta ttgttctggc taactccgtc ataacttgcc ctctaccgct
    50941 ttgcggcaaa actcaaaaaa aaacctgaaa aaaacggcct gacgtgaatc aagcaatttt
    51001 tttcaggttt tgcccgctta gtgcggtaac aatcctttat tcagtaataa tatttcagtg
    51061 ttctttgcgc acgcgctcta tatttatggc taaaaacata atctctgcag gtgagatttt
    51121 acgttgatac tgcaaaccaa taaaaatggc gatccgctcc gcacattgcc atgcttgcgg
    51181 gtaattttgc tttactgctt attgtaatga ttcatcacta tcgttaatcg atgcatgttc
    51241 aataatacgc caggataaaa atttcagatg cgtaaccagt cgctgataac tcaagctttc
    51301 ttcctggtaa ttaaggctga actgaaattt tattaattgc agcatttctc gcattaattg
    51361 cgtgacacct gcaacatcct ccatatttcc gctcatttgg gcactgacca gatgcatggc
    51421 aataaagccc acttcatctt tcggtaactg cacgcccaac cgtttatcaa taatggttaa
    51481 cgcttcttcc cctagctgga actctttcgg gtaaagtcgc tggatatccc acagcagcgg
    51541 gttgggcagt agcacgtttt gctgaaagcg tttaatcgca aactggcaat ggtcagttag
    51601 cgagatataa atactgtcct gcaactttcc cagacgctcc tgcgccagag agataatacg
    51661 atcacaggtt gccatcacct caagaggcat atgacttaag agttcgctta atcgcccgtt
    51721 cagttcatga ctgctcaagg catactcttt ttctattcca cttgagttaa ttctttcgcc
    51781 tgggcgtttt tgaaagccaa ttccgcgccc catgacgact ttttcccgct gttgatcatc
    51841 aataaccacc acaacattat tgttgagaat tttggtgatt tgcatgttca tagcaaggac
    51901 cttttttata aacaaaaaaa cccgacttca ccagtattct ctggttatgt caggttttgc
    51961 ctgcgaatgc agtaacaatc cagtcattaa ttaatggttt ttataacgaa catccaggtt
    52021 cgaaaattaa tttagttgcg tgcagaaaaa atagcaatgc tctatttata aaagtatgac
    52081 catgctcgca gttattaatt ttgtgtaatt ttaggatttt ataaagttat atataacaaa
    52141 tcccaataat taaattattg ggatttactt ggtgaattat ttatcgctat ctttttctgc
    52201 cagcagttta tcgagctcgt caccaccgac gtgacggaaa tcctgcccct tcacgtagta
    52261 gaagataaac tcacaaatat tctggcagcg gtcgccaata cgttcgatag aacgcgcaca
    52321 gaataacgcg gtaagtacgc tcggaatggt acgcgaatct tccatcatgt aggtcatcag
    52381 ttgacgaaca ataccttcgt actcctgatc gactttttta tcttcacgat aaatacgtac
    52441 cgcttcgtca atgtccatcc gcgcgaacgc gtccagcacg tcgtgcagca tctggatggt
    52501 atgacggccc agcgactcca gacttaccag caacggctga tgctgctggg agaatttctc
    52561 cagcgcagta cggcagattt tatccgccac gtcaccaata cgctccagct cggcaatggt
    52621 tttactgatt accatcacca gacgcaggtc gctcgccgtc ggctgacgtt tggcgataat
    52681 gcgcacgcag gcttcatcga tcgccacttc catcatgttg acgttcttgt cgccttcgat
    52741 gacgcgcttc gccagatcgc tgtcctggtt atgcatcgcg gtgattgcat cagaaagctg
    52801 ctgctccacc atgccgccca tggtcatcac ctgcgtgcgg atgctttcca gttcggcgtt
    52861 gaactggccg gaaatatgtt tattaagatt gagactgtcc ataacgcact cctgaatcaa
    52921 ccgtaacgac cggtgatgta gtcttctgtt tgttttttcg ctggcttggt gaacagatcg
    52981 tccgtgttgc tgaactcaat caattcgccc aggtacataa acgccgtgtg gtcggaacaa
    53041 cgcgcagcct gctgcatgtt gtgggtgacg atcaccacgg tgtaatcctg cttcagttcg
    53101 gtgatcagct cttcaatacg cccggtagag atagggtcga gtgccgaaca cggttcgtcg
    53161 agcagcagca cttccgggcg aatggcgata ccacgcgcaa tgcacagacg ctgttgctga
    53221 ccaccagaga gagagtaacc gctctggtgc aatttatctt tggtttcgtt ccacaatgcg
    53281 gctttggtca atgcccactg cacgcgctcg tccatgtcgg cacgggagag cttctcaaac
    53341 agacgcacgc caaaggcgat gttgtcgtaa atggacatcg ggaacggcgt cggtttctgg
    53401 aacaccatgc ccactttcgc acgcagcagg gcgatatcct gagagttggt caggatgttg
    53461 tcgccatcga gcagaatttc accttccgca cgctgctccg ggtacagttc aaacattttg
    53521 ttgaaggtac gcagcagcgt tgatttaccg cagccggacg gcccgataaa cgccgtaacc
    53581 tggtttttgg cgatatccag gttgatgttt ttcagggcat ggaatttgcc gtagtagaag
    53641 ttcaaattac gaacctgaat tttactcggg gcagtttcaa ccatactcat tgcaatcttt
    53701 tcctcatcgt gcctgatgca cttcgcgaat caggcttacc gtaggccgga taaggcgttt
    53761 acgccgcatc cagcaaagtg ttaaccgtgt ttattcttcg caaaaacaac gcgcgccaga
    53821 atgttcagca gcagtacgca cagggtaatg atcaacaccc cggcccaggc cagttgctgc
    53881 cattccgcaa acgggctcat cgcaaactta aagatcgtca ccggcaggtt ggcgatcggc
    53941 tgcatcatgt ccgtgctcca gaactggttg gagagcgcag taaacagcag cggtgcggtt
    54001 tcaccagcaa tacgggcaat cgccagcagg ataccggtca tgatcccgga caccgacgct
    54061 ttcagcgtga tcgaggcgat catcttccac ttcggcgtac ccagcgcata agccgcttca
    54121 cgcaggctgt ccggcaccag tttcagcatg ttctcggtgg tgcggataac aatcggcacc
    54181 tgcaacagcg ccagcgcaat cacgcccgcc cagccggaga agtgctccat ctgcgccacc
    54241 acgatggtgt aaacaaaaag accaaccaca atcgacggcg cggagagcag aatgtcgtta
    54301 atgaagcgaa tcacttctgc cagccaggat ttacgaccat attcagccag gtaaatcccc
    54361 gccataatgc ccagcggcgt accgaatacc gtagcccaca aaattaacag gccgctaccc
    54421 gccagggcgt tcgccagacc accgccttcc gtattgggtg gtggcgtcat ttcggtgaac
    54481 agcgccagcg acataccgtc gataccgcga gtgatggtgg acattaaaat ccagatcagc
    54541 cagaacagac cgaaggccat cgtcgccatt gagagcgtca gcgcaatacg gtttttgagg
    54601 cggcgacgcg cctgcatttt gcggcgggat tcagccagtg ccgcagtggt ttgcatttca
    54661 accatagcca ttagcgtgcc ccctcattct tagccaggcg cataatcata aacttcgatg
    54721 cggcgaggac gatgaaggta atcacaaaca ggatcaggcc cagttccatc agtgcagcaa
    54781 cgtgcagacc cgactctgct tcggcaaatt cgttcgccag cgcagaggtg atactgttgc
    54841 ccggcatgta cagcgaggcg ctgtcgagct ggtaggtgtt accgatgata aaggtcaccg
    54901 ccatggtttc accaagcgcg cggcccagcc ccaacataat gccgccgata acaccatttt
    54961 tggtgaacgg aagaacgata cgccagataa cttcccaggt ggtgcagcca ataccgtagg
    55021 ccgactcttt catcatcacc ggggtttgtt cgaacacatc gcgcattacc gccgcaatgt
    55081 acggaataat catgatggcg aggatcacgc ctgccgcgag gataccgata ccaaaggccg
    55141 ggccggagaa cagcgcgccg acaatcggga tattcgacat gatattgccg accggctcct
    55201 ggaagtaaac ggcgaacagc ggcgcaaaga taaacaggcc ccacatgccg taaacgatac
    55261 ttggaatggc tgccagcagc tcaatggcga tacccagcgg gcgcttcagc cagccaggcg
    55321 caagctcggt caggaacagg gcgataccga aactcaccgg gacggcgatc agcagcgcga
    55381 taaacgaggt caccagcgta ccgtagatcg gcaccagcgc cccgtagata tcgttcggcg
    55441 catcccactc tttggtccac aggaaagcca gaccaaattt ctgaatgctc ggccaggagg
    55501 agatgatcag agagacaata atgccaccca acatcaatag cacaatcagc gccgccagtt
    55561 ttaccagcac gctgaaaatt atgtcgccct ttttacccgg tgggttaaaa gcaggcttgg
    55621 ttgcagccat aagttactct tcagttaaac gcgtttacaa agtcattttg taatgccgga
    55681 tgcggcgtaa aacaccgtac ccggcctgag ttttattagt acagcggctt gccgctactg
    55741 tctttaatat tggtcttcca cgcagcgcga acctgttcca ctacgctatc cggcaggctg
    55801 gcgtaatcca ggtcgttcgc ctgtttagcc ccggttttgt atgcccagtc gaagaacttc
    55861 agcacttctg tgccttgttc tggtttcttc tgatctttgt ggatcagaat gaacgtggta
    55921 gaggtaatag gccacgcatc ttcgcctttc tggttggtca gatcctgagc gaatgttttg
    55981 ctccagtctg cgccttttgc tgcattagcg aagttttctt cggtcggact aaccggtttg
    56041 ccatcagcgg agatcaattt ggtgtacgcc aggttgttct gcttcgcgta agcatattca
    56101 acgtaaccaa ttgcacccgg cagacgctga acgaacgcgg cgataccgtc gttaccttta
    56161 ccgcccagac cgatcggcca ttttacggta gagccagtac caacgttgtt tttccactct
    56221 tcgttcactt tcgccaggta gctggtgaag acgaaggaag tcccggagcc atctgcgcgg
    56281 cgtactacag caatgttctg tgaaggcagt ttcagacccg gattcagttt ggcgatggct
    56341 tcatcatccc acttcttgat tttgcccagg tagatgtcgc cgagggtttt accatccagc
    56401 accagttcgc cagacttcag acctggaata ttaaccgcca gcaccacgcc gccaatcacg
    56461 gtcgggaact ggaacaggcc ttcctgagcc agtttttcat cagacagcgg cgcgtcagag
    56521 gcaccgaaat caacggtgtt agcgataatc tgttttacgc caccggaaga accgataccc
    56581 tggtagttaa ctttattacc ggtttctttc tggtaagtgt cagcccattt ggcatacacc
    56641 ggcgcaggga aggttgcacc tgcacctgtc aggcttgctt ctgcaaacac agagaaagca
    56701 ctcatcgata aggtcgcggc gacaacagtt gcgacggtgg tacgcataac tttcataatg
    56761 tctcctggga ggattcataa agcattgttt gttggctacg agaagcaaaa taggacaaac
    56821 aggtgacagt tatatgtaag gtttatgaca gttttatgac agagagagaa agtctttagt
    56881 ctgatttaaa taagcgttga tattcagtta attacaaata ttaataacga agagatgaca
    56941 gaaaaatttt cattctgtgt cagagaaaaa gtagccgaag atgacggttt gtcacatgga
    57001 gttggcagga tatttgatta aaaacataac aggaagaaaa atgccctgct tacgcagggc
    57061 atccatttat tactcaaccg taaccgattt cgccaggtta cgcggctggt caacgtcggt
    57121 gcctttgatc agcgcaacgt ggtaagccag tagttgcagc ggaacggtgt agaagatcgg
    57181 tgcaatcacc tcttccacat gcggcatctc aatgatgtgc atgttgtcac tgctcacaaa
    57241 acccgcatcc tgatcggcga agacatacaa ctgaccgcca cgcgcgcgaa cttcttcaat
    57301 gttggatttc agtttttcca gcaattcgtt gttcggtgca acgacgataa ccggcatatc
    57361 ggcatcaatc agcgccagcg gaccgtgttt cagttcgcct gcagcgtagg cttcagcgtg
    57421 aatgtaagag atctctttca gcttcaatgc accttccagc gcgattgggt actgatcgcc
    57481 acggcccagg aacagcgcgt gatgtttgtc agagaaatct tctgccagcg cttcaatgcg
    57541 tttgtcctga gacagcatct gctcaatacg gctcggcagc gcctgcagac catgcacgat
    57601 gtcatgttca atggaggcat ccagaccttt caggcgagac agtttcgcca ccagcatcaa
    57661 cagcacagtt aactgggtgg tgaatgcttt ggtggaggcc acgccaattt ccgtaccggc
    57721 gttggtcatc agcgccagat cggattcgcg caccagagaa gaacccggaa cgttacagat
    57781 tgccagcgaa ccaaggtaac ccagctcttt cgaaagacgc aggcccgcca gggtatccgc
    57841 ggtttcgcca gactgtgaca aggtgatcat caggctgtta cgacgcacgg cagatttgcg
    57901 atagcggaat tcagaggcga tttcgacgtc gcacggaata cctgccagcg attcaaacca
    57961 gtagcgggaa accataccgg agttataaga agtaccacag gcgaggatct gaatatgctc
    58021 aaccttcgac agcagttcat cggcgttcgg tcccagctcg cttaaatcaa cctgaccgtg
    58081 gctgatgcgc ccggtaaggg tgtttttgat cgcgttcggc tgttcgtaga tctctttctg
    58141 catgtagtgg cggtaaatac ctttatcgcc cgcgtcatat tgcagattgg attcgatatc
    58201 ctgacgtttt acttccgcgc cagttttatc gaagatgttt accgaacggc gagtgatttc
    58261 cgcaatatcg ccctcttcaa ggaagataaa acgacgagtc actggcaaca gcgccagctg
    58321 gtcagaagcg ataaagtttt cgcccatacc caggccaatc accagcggac taccagaacg
    58381 tgccgccagc agggtatccg gatgacggga gtccatgatc actgtaccgt acgcaccacg
    58441 cagttgcggg atagcacgca gaactgcctc acgcagagta ccgccttgtt tcagctccca
    58501 gttcaccaaa tgtgcaatca cttcggtgtc ggtttcagaa acgaaggtat agccacgcgc
    58561 ttttaactct tcacgcagcg gttcatggtt ttcgatgatg ccgttatgca ccaccacaat
    58621 gtgttcagaa acatgcggat gcgcgttagc ttctgaaggt tcaccgtggg tcgcccagcg
    58681 agtgtgagca ataccggtgc cgccatgcag aggatgttct tccgctgcct gagccagcat
    58741 ctgtacttta ccgaggcgac gcaggcgggt catatgacct tcagcatcca ccacggccag
    58801 gccggcagag tcatatccgc gatattccag acgacgtaaa ccttcaagaa ggatttctgc
    58861 tacatcacgt tgcgcgatcg cgccaacaat tccacacata gtttttgatt ccgatttata
    58921 tcgttgtcgg tcaacctgta tgcccgtttt ttcgggcgcc ccgagccttg tagagagtgg
    58981 ggttattttt atagttactg cttgtgggcg ggagattatg ttatctcctc atcccatatg
    59041 accggattac ccgaccagaa ttactttttc tttatcggac gacgccagcc ttctttttga
    59101 gtctgcggca cacggctgat agccagggca ttttcgccga cattacgcgt cacagttgta
    59161 cccgcagcaa tggtcgcgcc tttgcctact gttaccgggg ccaccagttg agtgtcggaa
    59221 ccgacaaaca catcgtcgcc gataatggtc ttaaatttat tcgcaccatc gtagttgcag
    59281 gtaatggttc ccgcaccgat gttaacgtta tcgccaattt ccgcatcgcc caggtaagtc
    59341 agatgaccag ctttcgagcc tttacccaga cgcgcttttt tcatctcaac gaagttaccg
    59401 acgtgtgcac cttccagcaa ctcagcacca ggacgcagac gggcaaacgg gccaatagta
    59461 caggccgctg ccagattcgc atcttccacg acggtatatg gactgatttc gcaatcatcg
    59521 ccaatcacgc tgtttttaat cacgcaaccg gtgccgattt tcacgcgatg accgagagtc
    59581 acgttgccct cgatgataac gttagtatca atttcaacat cgcgcccgtg agtaagcgta
    59641 ccgcgcagat caaaacgcgc cggatcgcgc agcataacgc ctgctaacag cagtttttca
    59701 gcctgttcgg actggtaaac gcgctccagt cgggagagtt gcaggcggtt attcacgcct
    59761 tctacttcgc ttaaacgttg cggatgaacg gcgacgattt cacgtccttc ctgatacgcc
    59821 agcgcaataa tgtcggtgat gtagtattcg ccctgagcat tattgttggt cagcttcgcc
    59881 agccagcgtt tcatatctgc gccgttggca atcagaatgc cggtgttgat ctcctgaatc
    59941 tgacgctgct cgtcggtggc atctttgtgt tcaacaatgc cggtaacttt gccgttttca
    60001 cgggtgatac gtccataacc ggtcggatca tccagtttta ccgtcagcag accaatgcca
    60061 ccctgcggtt tagcatcacg cagacgctgg agtgtttcga cagagatcag cggcacgtcg
    60121 ccgtagagca ttaaaatgtc ttcatcatcg gcaaagaaag gtgcggcctg ctgcatcgca
    60181 tgacccgtac ccagctgttc tgcctgaagc acccagttca ggttgtcgtc tttcagcgcc
    60241 tgcttaagca gatcgccgcc gtgaccatac acaaggtgaa cgtgcgctgc gcctaattca
    60301 ttcgcagcat caatgacatg ctgaaccatc gctttcccgg caagggtatg cagcactttc
    60361 ggaagatcgg aatacatgcg cgtgcctttg cctgcggcaa ggatcactac gctcatagca
    60421 ttattcaaca tacgcgtcct gactgtaatt tgagaacgaa tttaaaccgc ttcaccttga
    60481 aaaaactaca tttttttcat cgtgaaatgg acagaggata aattgttcaa taacggatta
    60541 tccccgctga cgaaagcgcc attttcgacc atcgtcacgc cttttgtctg cagaaaatta
    60601 aggcagtacc ttcatttaag cgtcaggtgg atgtttttgc tcttatttcg atcaatgaat
    60661 aaacgggaaa acaggggtgt tttatatcat caggatctat gtgaacgctt ttcaggacgg
    60721 gtcaatacgc gtaaaaaaaa gccagcctgt tgccagactg gcttttgtgc ttttcaagcc
    60781 ggtgttacat cgcttttttg gtcaactcga taacgcgcag ctgcgcgatc gctttggcca
    60841 gttccgcaga cgcctgagcg taatctacgt cgccgtgaga gctgctaatg tgctcttcag
    60901 ccttacgttt cgcttccatg gctcgcgctt cgtcgagatc ctggccgcga attgcggtgt
    60961 cggccagaac ggtcacgttg ccaggctgca cttcaagaat gccgccagac agatagataa
    61021 actcttcgtg accgtgctgt ttcacgatgc gaatcatacc aggcttaatg gcggtgagca
    61081 gcggtgcgtg gccagggtag atccccagtt caccttcgct acccgttacc tggattttct
    61141 cgaccagacc agagaacatt tgttgctctg cgctgacgac gtccaggtgg taagtcattg
    61201 ccatatcacc ctccgattaa ggcgttaaag ttttttggct ttttccacag cttcttcgat
    61261 ggaaccgacc atgtagaacg cctgctccgg caggtgatcg tattcgcctt ccatgatgcc
    61321 tttaaagcca cggatggtgt ctttcaggga gacgtattta cccggagaac cggtgaatac
    61381 ctctgccacg aagaacggct gggacaggaa gcgctggatc ttacgagcac gcgctaccac
    61441 cagtttgtct tcttcagaca gttcatccat acccaggatg gcgataatgt ctttcagttc
    61501 ctgataacgt tgcaggatgg actgaacgcc acgcgcggtg tcgtagtgtt cctgaccaac
    61561 caccagcggg tccagctgac ggctggtgga gtccagcggg tcaacggccg ggtagatacc
    61621 cagagacgcg atctgacggc tcagtaccac ggttgcgtca aggtgcgcaa aggtggttgc
    61681 cggagacggg tcagtcaggt catccgcagg tacgtatacc gcctgtacgg aggtgataga
    61741 accggttttg gtggaggtga tacgttcctg cagaacgccc atctcttccg ccagggtcgg
    61801 ctgataacct accgctgaag gcatacggcc cagcagtgcg gatacttccg taccggccag
    61861 ggtgtaacga tagatgttgt caacgaacag cagaacgtca cgaccttcgt cacggaattt
    61921 ctcagccatg gtcagaccgg tcagagcaac gcgcagacgg tttcccggcg gctcgttcat
    61981 ctggccatac accagggata ctttgtcgat aacgttggag tcggtcattt cgtggtagaa
    62041 gtcgttaccc tcacgagtac gttcacctac gcccgcaaac acagagtaac cggagtgctc
    62101 gatcgcgatg ttacgaataa gctccatcat gtttacggtt ttacctacac ccgcaccacc
    62161 gaacagacca actttaccgc ccttagcgaa cggacacatc aggtcgataa ctttgatacc
    62221 ggtttccagc agttcctgag agtttgacag ctcttcgtag gaaggtgctg cgcggtgaat
    62281 cgcccaacgc tcttcttcac cgatctcgcc tttcatgtcg accggttcac ccagtacgtt
    62341 catgatacga cccagagtcg ctttacctac cgggacttcg atcgggtgtt cgaggtcttt
    62401 tacatccaga ccgcgacgca gaccgtcgga ggaacccatt gcgatggtac gcacgatacc
    62461 gccgccgagc tgctgctgaa cttccagcac cagacgctca ttaccatttt gcacctcaag
    62521 agcatcgtac acgcgcggta cggcatcctg agggaattcg acgtcaacta cggcgccgat
    62581 tacctggaca atctttccag tagccatctt aaatcctcta cgaaataacc tgtttaaacc
    62641 gcggcggccc ccgagacgat ctcggtgagt tcctgagtaa tgctggcctg acgagctttg
    62701 ttgtatacca actgcagctc tttaatcagg ctgccgccat tgtcggtcgc ggctttcatc
    62761 gccaccatac gggcggcctg ctcgctggcc aggttttcaa ccacgccctg ataaacctga
    62821 gattcgacat aacgacgcag cagggtatcc agcaacgcct tcggatcggg ttcgtacagg
    62881 taatcccagg atttatgttt cagatcatca tcatctgatg ccggtaacgg cagcagctgg
    62941 ctgatggtcg gaacctgaga catggtgtta ataaatttgt tgctgacaat gtaaagcttg
    63001 tccagacggc cttcgtcgta ggcctgcaac atcactttta ccggaccgat cagttcggac
    63061 aaggaagggt tatcccccat gccggtgacc tgggcaacaa cattgccgcc cacggagttg
    63121 aagaacgaca cgcctttcga gccgatcatt gcgaggtcgc attgaacgcc tttgtcggtc
    63181 caggtcttca tttccgccag cagttttttg aacaggttaa tgttcaaacc accgcacaaa
    63241 ccacggtcgg tcgacaccac caggtagccc acgcgtttaa cgtcgcggtc ttccaggtaa
    63301 gggtgcttat attccagatt accgtgtgca aggtgaccaa tcactttgcg catggtttct
    63361 gcataaggac ggctggccgc catgcgatcc tgcgatttac gcattttgga agcggcgacc
    63421 atctccatcg ctttagtgat cttttgcgtg ttctggacgc ttgcgatctt actacgtatc
    63481 tcttttgcgc cggccatgag cttctcctca atgccttgcg gcctgcccaa aggcaagccg
    63541 ccagacgtta ccaggattgg gttgctttga aggaatcgag gatgcctttc agcttgcctt
    63601 cgatttcgtc gttgtagcca ccggtctggt tgatctcttg catcaacgga gcgtgatcac
    63661 ggtcgacgta agccaacaga gcggcttcga agctgccgat tttcgacagt tcaacatccg
    63721 ccaggtaacc acgttctgct gcgaacagaa ccagagactg ttgcgcaaca gacatcggcg
    63781 catactgttt ctgcttcagc agttcggtca ctttctgacc gtggtcaagc tgcttacgtg
    63841 ttgcatcgtc aaggtcggat gcaaactgag agaacgctgc cagttcacga tactgtgcca
    63901 gagcggtacg gataccaccg gacagttttt tcatgatctt ggtctgtgct gcaccaccaa
    63961 cacgggatac ggaaataccc gggttaaccg caggacgaat accggcgttg aacaggttgg
    64021 tttccaggaa gatctgacca tcggtaatgg agattacgtt ggtcggaacg aacgcagaaa
    64081 cgtcacccgc ctgagtttcg ataatcggca gcgcagtcag agaaccggtt ttccctttca
    64141 cttcaccttt ggtgaaagct tcaacgtatt cggcgttaac acgcgcagca cgctccagca
    64201 gacgagagtg gaggtagaat acgtcgcccg ggaatgcttc acgtcctggc ggacgacgga
    64261 gcagcaggga gatctgacgg taagcaacag cctgtttaga caggtcatcg taaatgatca
    64321 gcgcatcttc accgcggtca cggaagtatt cacccattgc gcaaccagcg tacggtgcca
    64381 ggtattgcag tgcagcggat tcagacgcgg ttgctaccac aacgatggtg ttagccagtg
    64441 cgccgtgctc ttccagttta cgtaccacgt tagaaatggt ggacgctttc tggccgatag
    64501 cgacatagat acatttgata ccggaatcgc gctggttgat gatggcatcg atagccagtg
    64561 cggttttacc ggtctgacgg tcaccgatga tcaattcacg ctgaccacga ccgattggga
    64621 tcatggagtc aacggcttta taaccggtct gtaccggctg atctacggac tgacgttcga
    64681 taacgcccgg agcgattgct tctacagcag agaagccgtc gtgatccagc ggacctttac
    64741 catcgattgg tgcacccaga gtgttaacca cacggcccag caggccacgg ccaaccggaa
    64801 cttccaggat acggccagta cacttaactt tcatgccttc ggcaaggtca gcgtacggcc
    64861 ccataacaac cgcacctaca gagtcgcgct cgaggttcag tgcgatagcg taacggttac
    64921 ccggcaggga gatcatttca ccctgcatac aatcggccag gccgtgaatg cggataacac
    64981 cgtcacttac agaaacaata gtaccttcgt tgtgagcttc actcacaaca ttgaactgag
    65041 caatgcgctg cttgatcagt tcgctgattt cggtggaatt cagttgcatg ctccagtccc
    65101 cttaagactg caagacgtct gcaaggcgct caagacgacc gcgtacgctg ccatcaatga
    65161 ccatatcacc cgctcggatg ataacacctg ccattacaga cttatcgatt ttgcaattca
    65221 gcttaacttt gcgtgacaga cgtttttcca tcgcagcaga aattttcgcg agctgttgtt
    65281 cactcaacgc ggcagcggaa atgacgtcta cctcagcggt agcctcactc acagcacgca
    65341 ggtgaataaa ctgctccaga acatccggga gcgcgttaag acgaccattt tcggccatta
    65401 cccgaatcag gttctgaccg ttttcgtcca gttgctcacc acaaactgcg ataaacgact
    65461 cggcgagcgt ttctggcgca agcgcgccag agagaagctc tgccatttgt tcgtttttgg
    65521 ttacctcggc ggcaaacgcc agcatgtcct gccagcgttc tacactttgg tgttcgacgg
    65581 caaagtcaaa agctgctttg gcgtaggggc gagctaccgt aataaattca gacatcagcc
    65641 cctccctcct tacagttcag cgacaagttt atccacgatg tcgctgttag cagcttcatc
    65701 cacggaacgt tcgatgatct tctcggcgcc agcaacagcc aggatagcaa cttgcttacg
    65761 cagctcttca cgggcacgtt tacgctcggc ttcaatttcc gcctgcgcct gggccacgat
    65821 tttagtacgt tcctgttctg cctcagcttt cgcttcatcc agaatctgcg agcggcgttt
    65881 gttagcctgc tcgatgatta cctgggcttc cgctttcgct tttttcagct ggtcggtcgc
    65941 gctggccttt gcaaggtcaa ggtccttatg tgctcgttct gcggaagcaa ggccgtcagc
    66001 aatttctttt tgacgttttt cgatggctgc cattaatggc ggccatacgt acttcatgca
    66061 gaacagaacg aacaggacaa acgcgatggc ctggccgagg attgttgcgt taagattcac
    66121 agcacaatgc ctctatttag ttaacgttct gatattgctc tttaaataaa agcaacgctt
    66181 actacgcgac agcgaacatc acgtacagac ccagacctac agcgatcatc gggatagcat
    66241 ccaccagacc cataacgata aagaactgag tacgcagcag aggaatcaga tcaggttgac
    66301 gcgctgcgcc ttccaggaat ttacccccga ggatgccgat accgatcgca gcaccgattg
    66361 ccgccagacc catcatcaca gcggcagcca tgtacagcag atccatattc aggttttcca
    66421 tgacagtctc cagtttgttt cagttaaaac gtagtagtgt tggtaaatta atgttcttca
    66481 gacgccatcg acagatagac gatcgtcaga accatgaaga tgaaggcttg cagcgtaatg
    66541 atcaggatgt ggaaaatggc ccacggcaca ttcaggatcc actgtgacca ccacggcaac
    66601 agaccagcaa tcagaatgaa aatcagctca ccggcataca tgttaccgaa cagtcgcaaa
    66661 ccgagtgaaa ctggtttgga cagcaggctt accccttcaa ggattaagtt gacaggaatg
    66721 aacgcccagt gattgaacgg ctgcagcgtc aactctttcg tgaagccgcc gatgcctttc
    66781 attttgatgc tgtagaacag aatcaggata aatacgccca gtgccataga cagcgttacg
    66841 ttcacgtcag cagacggaac cacacgcagt gcaggcagac ccagtacatg ttcagcaatg
    66901 tacggcagca ggtcgatagg cagtaaatcc atcaggttca tcaggaatac ccagacgaag
    66961 atcgtcaggg ccagcggagc aatcagcttg cttttgccat ggtacatgtc tttcacgcta
    67021 ccattaacaa agccgatcac cagctcaatc gcggtctgaa acttacctgg cacgccgctg
    67081 gttgcctttt tggctacact acggaataaa accaggaaca acagacccag caccaccgag
    67141 aagaacatgg agtcaatatt gattgtccag aaggtggctg gggggttatg tggatccacc
    67201 agcgagaatg tacgcaggtc cagctgaagg ttattcaggt ggtgtcctat gtaatcctgc
    67261 ggcgtcatat tttctgaagc catgatgcct tttacccttt gttgttaatt acagccggtg
    67321 ccagtatctg aaccaccagc accaaaaccc acgtaacgat cagcggcaag aataccgcct
    67381 ttaaaaccgc caacgccacc accagtaaca ccaacatcgc cagaactttg aaagcttcgc
    67441 caaatgcgaa tgtccaggcc acccggcctt tcgctggtgt atgcgcctgg tgacgccagg
    67501 caaatatcat aaacaaaacg ttaggcagaa agactgccag gcccccgctt attgcagaga
    67561 cgccccagaa ggggtctttg aggctgaaca gcaatccact tgctatcacc accagtaact
    67621 gaacgagcag aagcttccga gcaacgtttc gactcacgag cgacacagac atcacgtttt
    67681 tcactcctgc tcccttcgag gtatgccgcg tgtcgtataa aactttcttt aaggcttaga
    67741 gtcaagcatc aaaaagcggt caaattatac ggtgcgcccc cgtgatttca aacaataagt
    67801 agccaaaagg tgaataaatg tttaaatatt tttccagtgc atacaattgc gacttttctg
    67861 caaaccctgt tcgatcatga aaaactgtaa ataacgcgta aacactggtg ataaagcgtg
    67921 cttcagatca catattgcgc atgttcgcgc acagcatatt tatttacttg gcaaatgatg
    67981 cctttgcaag tttatgatat ttcagtctaa aaacagatac tgttttaata aatgacattt
    68041 acataacaaa aaccagccat tgacattttt aataatgttt taacagtcaa tgatgattct
    68101 tagcgccgat ttttagcaga ctgatatttt cacttatgac ttattttctg cttaccaaaa
    68161 aaagccacgt tatcttgttg atacaaaaga gtgaacgtgg cgttaaatgt aaccagttat
    68221 atcagtagaa aacctggttg ttgttaacag tctaaccggt caatttttta tgattttttt
    68281 gataaaaatt aaattttatt tgctttaatc accaccagat gacgttcgcc atccagggct
    68341 ggaacctgaa gtttaaccac tgattcgacc tgatattctt cgggcaacaa agcgatttca
    68401 tcttccggca tttgcccttt cagcgcgtag aaacggcctt gctcaccagg aagatggtgg
    68461 caccagctca ccatatcgtt cagagaggca aaagcgcggc taattacgcc atcaaatggc
    68521 ggctctgacg gaaactcttc taccctgctc tgtactggct caatattctc cagtttaagc
    68581 tcatgttgca cctgacgaag gaaacgcacg cgtttaccaa ggctatccaa caacgtgaaa
    68641 tgagcttcag gacgcacgat agagagtgga atgccaggca gtcccggtcc ggtgccgaca
    68701 tcgataaacc gttcaccttg cagatacggt gccaccacaa tgctatcgag aatatggcgt
    68761 accagcatct cattaggatc gcggaccgaa gtcaggttgt acgctttatt ccatttatgc
    68821 agcatattca cgtaggcaat aagctggttt ttctggtgat cggtaagcga aatacctgcg
    68881 tctttcagca gtaaggagag tttgttgagc acggtgatta cctgttcttg atgcgttgcc
    68941 tggtaagcgg gtgcttacca ggcattttta atgcgttatg cgctacgacg cagcataccc
    69001 tgttttttca gccacaccag cagaatggag atagccgcag gcgtgacgcc agaaatacgc
    69061 gaagcctggc caatagaggc cggtttgtga tcgttaagtt tggcgatcac ttcgttagaa
    69121 agaccggata cctggcggta atccagcgtc gctggtagca gggtattctc gttacgcagc
    69181 tgcttttcga tctcatcttg ctggcgcgcg atataacctt cgtatttaac ctgaatctca
    69241 acctgttccg cagcctgttc atctgtcaac gcaggggcaa acggtgtcag cgtggttaat
    69301 ttttcataag tcatttcagg acgacgtagc agatcttcac cactggcttc acgggaaagc
    69361 ggcgcagtca ggtgagcatt cacttcggct gcagcttccg ccgacggggt tacccaggtc
    69421 gatttcagac gctgacgctc acgctcgata ttctcaagtt tctcgttaaa gcgcgcccaa
    69481 cgttcgtcat ccaccaggcc cagttcacga ccgatttcag tcaaacgcag atcagcatta
    69541 tcttcgcgca gcatcagacg atattctgcg cgcgaggtaa acatacgata cggttctttg
    69601 gttcctaaag tgcacaggtc atcaaccagt acgccgagat acgcctgaga acgcgccgga
    69661 gcccaacctt ctttgtcagc agacagacgg gcagcgttaa gaccagccag caaaccttgc
    69721 gcagcggctt cttcgtaacc ggtagtgccg ttaatctgac cagcaaagaa cagcccctgg
    69781 ataaacttgc tctccagcgt cggtttcagg tcgcgtggat cgaagaagtc atactcaatg
    69841 gcataacccg gacgcacgat cttcgcgttt tccatcccct gcatggagcg gacgatttgc
    69901 atctgcacat cgaacggcag gctggtggag ataccgttcg gataaatttc gttagaggtc
    69961 agcccttccg gttcaaggaa gatctgatgc tgatttctgt cggcaaagcg catgactttg
    70021 tcttcaatcg acgggcagta gcgtgggccg acaccttcga tcacccctgc gtacattggg
    70081 ctacgatcga gattactgcg gatcacatca tgggttttct cgttggtatg agtgatataa
    70141 cacggcacct gctggggatg ctgggacgca ttgcccataa acgagaatac cggcattggg
    70201 ttatcgccat gctgttgcgc cagtacgcta aagtcgatgg ttcgagcatc aatacgcggt
    70261 ggtgtcccgg ttttcagacg accaacgcgc agcggcagtt cacgcaaacg gcgagaaagc
    70321 ggaatggacg gcggatcacc agcacggcca ccgctgtaat tatccagacc gatatgaatt
    70381 ttaccgtcga ggaacgtccc aacggtgagc acgacagctt tggcacggaa cttcagtccc
    70441 atttgggtaa cggcaccgac cacgcgatcg ttttcgacaa taagatcttc aaccgcctgc
    70501 tggaagatca tcaggttcgg ttggttctcc agcgccgtac gtaccgcctg acggtagagc
    70561 acacgatctg cctgagctcg ggtagcgcga accgccggtc ccttgcttgc gtttagtatc
    70621 ctaaactgga tacccgcctg atcgatcgct ttcgccatca gaccgccgag tgcatccact
    70681 tcttttacca gatgtccctt cccaataccg ccgatcgccg ggttgcagct catctgcccc
    70741 agagtgtcga tattgtgtgt caaaagcaga gtctgttgac ccatacgcgc cgcggccatc
    70801 gcggcctcgg tgcctgcatg acccccgcca atgatgatga cgtcaaaagg atccggataa
    70861 aacatggtga ttgcctcgca taacgcggta tgaaaatgga ttgaagcccg ggccgtggat
    70921 tctactcaac tttgtcggct tgagaaagac ctgggatcct gggtattaaa aagaagatct
    70981 atttatttag agatctgttc tattgtgatc tcttattagg atcgcactgc cctgtggata
    71041 acaaggatcc ggcttttaag atcaacaacc tggaaaggat cattaactgt gaatgatcgg
    71101 tgatcctgga ccgtataagc tgggatcaga atgaggggtt atacacaact caaaaactga
    71161 acaatcgttg ttctttggat aactaccgtt tgatccaagc ttcctgacag agttatccac
    71221 agtagatcgc acgatctgta tacttatttg agtaaattaa tccacgatcc cagccattct
    71281 tctgccggat cctccggaat gttgtgatca agaatgttga tcttcagtgt ttcgcctgtc
    71341 tgttttgctc cggaattttt gagttctgcc tcgattttat cgatagcccc acaaaaggtg
    71401 tcatattcac gactaccaat accgattgcg ccaaagcgga ccgcagaaag atcgggcttc
    71461 tgttcctgca atgcttcata gaaaggagaa aggttgtccg gaatatctcc ggcaccgtgg
    71521 gttgagctga taaccagcca gatccccgag gcagataaat cttccaacag cggaccgtgc
    71581 agcgtttcgg tggtaaaacc cgcctcttcc agcttttcag ccaggtgttc tgctacatat
    71641 tcggcaccgc cgagggtgct gccgctgata agagtgatat ctgccataaa ccgccacctt
    71701 tattaagagt ggcgtattgt acgctgtgaa cgcgttggga tctacctgtg gaaaagtatg
    71761 ggattaaaaa agccgatcag ggcttaatgg tacgcatgat cgggttctgc aggacgatca
    71821 gtgtctcggt ggactgaatt tcatcaattg tttggatctt gttgataagt acatgctgga
    71881 gagcatcgat cgaacggcac atcactttta taaagatgct gtagtggccg gttgtgtaat
    71941 aggcttcagt gacttcatcg aggctttcca gctttgccag cgcggaagga tagtctttgg
    72001 cgctctttaa tataatgccg ataaagcagc ctacgtcata accaagctgc ttcgggctga
    72061 catcaatacg cgccccggta atgatccccg cctgcttcat tttctctact cgaacgtgaa
    72121 tcgtccccgg actgacgcca aattgtttcg ccagttcggc gtaagcggtg cgcgcattgc
    72181 ccattaatgc ttccaggatg ccacggtcca gattgtcgat cagataattt tccataggat
    72241 tttcttatgc ggattgatga ttcattctat tttagccttc ttttttaatg aatcaaaagc
    72301 acgtgaggct ttttattgaa tgattattgc atgtgtgtcg gtttttgttg cttaatcata
    72361 agcaacagga cgcaggagta taaaaaatga aaaccgctta cattgccaaa caacgtcaaa
    72421 ttagcttcgt gaaatctcac ttttctcgtc aactggaaga acgtctgggg ctgatcgaag
    72481 tccaggcgcc gattcttagc cgtgtggggg atggcacgca ggataacttg tcgggctgtg
    72541 aaaaagcggt gcaggtaaaa gtgaaagctc tgcctgatgc ccagttcgaa gtggttcatt
    72601 cactggcgaa gtggaaacgt cagaccttag ggcaacacga cttcagcgcg ggcgaagggc
    72661 tgtacacgca catgaaagcc cttcgccccg atgaagaccg tctttccccg ttgcactcgg
    72721 tctatgtaga ccagtgggac tgggaacgcg taatgggcga cggcgagcgt caattctcga
    72781 ctctgaaaag cacggtagag gcgatctggg cgggaattaa agcaaccgaa gctgcggtta
    72841 gcaaagagtt tggcctggca ccgttcctgc cggatcagat ccacttcgta cacagccagg
    72901 agttactgtc tcgttatccg gatctcgatg ccaaagggcg tgagcgggcg attgcgaaag
    72961 atcttggcgc ggtattcctc gtcgggattg gcggcaagtt gagtgatggt catcgtcacg
    73021 acgtgcgcgc accggattat gatgactgga gcaccccgtc agagctgggc catgcgggtc
    73081 tgaacggcga tattctggtg tggaacccgg tactggaaga tgcgtttgag ctttcttcca
    73141 tggggatccg cgtggatgcc gacacgctga agcatcagct ggcgctgacc ggtgacgaag
    73201 atcgcctgga gctggagtgg catcaggcgc tgctgcgcgg tgaaatgccg cagaccatcg
    73261 gcggcggtat cgggcagtct cgtttgacca tgctgctgct gcaactgcca catatcggcc
    73321 aggttcagtg tggtgtatgg ccggcagctg ttcgcgagag cgtcccttct ctgctgtaat
    73381 aatttatcgc cgccagcgtc tgagcaggcg gcttcgcatc ccggtatcaa agcgccagat
    73441 atgatcgaaa atgcgcatga tgccgggttt gccatgtgca gacatcgcca cggcatgaaa
    73501 gcgatgctga tgtacccgct gtagctcttt cactttactc gtcacgtcgt caggcaaccg
    73561 ctgggcgata aaatcagaaa tcaccaccgc atcggcatca aaccattccc ggctttgcaa
    73621 gcgttccata atggcgcgaa aacaactggc aagatcggtg ccgccacgaa actgctgact
    73681 taaaaaacgg attgcttgtt cgatgccttg tgggcctgaa agctcataac ggacgatctc
    73741 ggtggaaaat agcataatat agcagcgccg gttttcagcg agagcaatgc gcatcaaggc
    73801 caggcagaac gctttcgcac actgttcatt aaagccgccc attgagccgg aagtatccac
    73861 acagacaata aacggtccgc gcggctgttc gtcgtaatct ttatgcacca ccgggcgttc
    73921 gatcactttt tcacgccacg actcaccatg caggcgatag gtgagcaact gtttttccac
    73981 cagccgacgg taaaactcat actccagttc tgttatccct agtgtcgcca gttctggcgg
    74041 caggagacgt aaaatatcat cgctttgttg cagaccatca acctgctcag gaaccgtcgc
    74101 cggttcgcgc accagggtgc ggaaggtttc catctgcgca tcgttgcgcg gtattgattt
    74161 ggcttcccgg gaacgcccca gctgttctgc caggcgtttc agttccggct gttcgttaag
    74221 aaattcaccg tatttcacaa tcaactgata gtcgccacgt ttaagctgac cggcgctcat
    74281 atcccacaga cgaccagctg cggtattgtt atctgcgaga atcggttcaa gttgtccgct
    74341 cagcgtcatg cgttcctgaa cttcactcaa cagttgttcg cgttcttctt ctaatagctg
    74401 ttgatttaac gtcgttgctt gcacgatcag acttaaacgc caacgctgga gaaaaagcgt
    74461 gtgtaacgct gaagtgatcg tgctgttagc atcaaccaac tgtcgggctt gttctgccca
    74521 tggggaattc agacgatgca gtaagtccag gatctgtggt agctgcacaa taaactgcgg
    74581 cgtggagagg agctggcttt gctgatagca catcacctct tcggtgagtt ccggcgggac
    74641 tcgggcatct ttcagccgac tgcgcagcgc ctcacgccag cggggaacat catcagtgat
    74701 tgccgccttc agtcgtggga atttttcaaa gaagactgcc agctgcggtg aggccagcag
    74761 cgcgatgatc atctcttcga tcaatccctc ttcgctgacg gccagcatca cattaagcgt
    74821 atccagcgtt agcattgttg tgcctggcga atctgtgcgc cgacatcctg taggctggct
    74881 tcaatgcgac ctaaccagtc gccagggata aacagacatt tttgctgttc gctgaataaa
    74941 gcgtgttgct tgcgccagtc gctttcaagc tcttccagtt gttgttttat ttcacctggc
    75001 agaccttcag ccgatgaacc gggaagtgcc agcgtactgc cttgtaaact tacatcgcgt
    75061 acaacaagat gttgggcgct atccacttcc agattcagtt tctgggcaaa gccgataccg
    75121 ttcagtttgc cgcgaatctc accaccttta ctcagccact gttccagcgc gctacgctca
    75181 aaggagatat gaaccacttc catatcatgc aattttaacg gtttttgcag cagcagagtc
    75241 agagtggaag cagtaacgtt aacaggaagt tgatactgct gacgacggct gaaaatgccg
    75301 cccagacgaa ttaccgttaa ggctgtttta tcgctttgtt gctgctggag ttgcaggtga
    75361 cgttgcacaa tcgcgcccag gcgggtcaac atcccttgct gttgccaggc atgaccggtc
    75421 atcaatacat caatttgttg ttgtatcaaa ttcaggcttt gcgcgtcata ccacaggcaa
    75481 tctttcagca aaatgagatc aaccggggca acagcactgc gaccgctaaa aaaggcgctg
    75541 gcctgcaata agcggatcgc ttttttccag cgacgatccg agacataagg cgcatccggt
    75601 aatttatcca gttgctggcg cagcataaaa atcagctcaa atacatgatc gggcagcgta
    75661 atttcaccaa tctctttctg ccagcgttca tattcttcat ctgtgatctg caaggaggca
    75721 ggaaccggat tgtcattttc atcctgttga ctggtcagca tggagcggaa attcgcttta
    75781 tcctgcactt tatctaacca cagacgaatc agcatgcggt catataacgc ttccagactg
    75841 ctgtctgctt ccggcagctc gttggaggcc gccaccagca gacgcatcgg gattttttct
    75901 acgagtgcgc cgttgcggaa ctggcgctcg ttaatggcgg tgagcaaggt attaagaatt
    75961 gccggacccg ctttccagat ctcatccaga aagacgattt cagcttccgg caggtaaccg
    76021 ctggttaaac gttcatagcg cccttcatct tttagcgcct gaatagaaag gggaccaaaa
    76081 acttcttccg gcgtggagaa gcgggtcatc agatattcaa acgcgcgggc attctgaaag
    76141 gcgaatttta agcgccgggc gatcaaactt ttggcaatac ctggtgggcc aaggaggaac
    76201 acactttcac cacttaatgc cgctaataaa cacaagcgga tggcgtggct acgttcataa
    76261 agcccctttt ccaacgaact gctcaggcgg gaaattcttt ccgctaataa atgagggtga
    76321 gccataatga agtggcgtcc tttcatcaaa agttctgcgt aaattgcgag tatagacgtt
    76381 tcttgctggt ggctaaaata gtctcaaagg aggggtattt ttctttgagc caggttaatg
    76441 tggccgcatt taggagtacg attttgccgt taatcgtgca tactgtgcgc ttttttgtgg
    76501 gccaagggac taagcacaca tttcatattt caacgaaaga ctagtctatg agcactgata
    76561 ataagcaatc attgcccgcg attaccctcg cggcgattgg agttgtctac ggcgatattg
    76621 gtaccagccc gttatataca cttcgtgaat gtttgtccgg ccagtttggt tttggcgttg
    76681 aacgcgatgc cgtgtttggc tttttatcgc tgatcttctg gctgctaatc tttgtggttt
    76741 ccattaaata tctcaccttc gtgatgcggg cagataacgc cggtgaaggg gggatcctga
    76801 cgttgatgtc gcttgccggg cgtaatacgt cggcgcgaac cacatcaatg ctggtgatta
    76861 tggggctaat cggcggcagc tttttctatg gtgaagtcgt cattactccc gctatttcgg
    76921 tgatgtccgc cattgaaggt ctggaaatcg tcgccccgca gctggatacc tggatagttc
    76981 ccctctcaat tatcgttctc acattattat tcatgattca aaaacatggc acagctatgg
    77041 tcggtaagct gtttgcgccg atcatgctga cctggttttt gattctggca gggctggggt
    77101 tacgtagcat tattgctaac ccggaagtgc tgcatgcact gaatccgatg tgggcggtgc
    77161 atttcttcct tgaatacaaa acggtttctt ttattgcatt aggggcagtg gtgctgtcga
    77221 ttacgggggt cgaggcgctg tatgctgata tggggcactt tggtaagttc cctattcgtc
    77281 tggcgtggtt caccgtcgta ttgccttcct taacccttaa ttacttcggc cagggagcgc
    77341 tgttgttaaa gaatccggaa gcgattaaga acccgttctt cctgttggca ccggactggg
    77401 cgctgatccc gctgctgatc atcgccgcac tggcgacggt aattgcctcg caggcggtta
    77461 tctctggcgt cttctcattg acgcgtcagg cggtacgtct gggatatttg tcgccgatgc
    77521 gcattattca cacctccgaa atggagtcag ggcaaatcta tattcccttt gtgaactgga
    77581 tgctctatgt cgcggtcgtg attgtgattg tcagctttga gcactccagc aacctggcgg
    77641 cggcgtacgg gattgcggtg accggaacca tggtgctgac gtctattctc tcgactaccg
    77701 tggcacgtca gaactggcac tggaataagt attttgttgc gctgatcctg attgctttcc
    77761 tttgtgtcga tattcccttg ttcaccgcta acctcgataa actgctctcc ggtggctggt
    77821 tgccattgag cctcggtacg gtgatgttta tcgtgatgac cacctggaag agcgagcgtt
    77881 tccgcttgct gcggcggatg catgaacatg gtaactctct ggaagcgatg attgcttcgc
    77941 tggagaaatc accgcccgtt cgcgtgcctg ggaccgcggt gtatatgtcg cgtgcaatca
    78001 acgtcattcc ctttgcgctg atgcataacc ttaaacataa caaggtattg catgagcggg
    78061 tgattctgtt aactctgcgc accgaagacg cgccatatgt ccataacgtc cgtcgggtac
    78121 agattgaaca actgtcgccc actttctggc gcgtggtggc aagttatggt tggcgagaaa
    78181 cgccaaacgt ggaagaagtt ttccaccgct gcggtctgga aggattaagc tgccggatga
    78241 tggaaacctc cttctttatg tcgcatgagt cgttgatcct cggcaaacgc ccgtggtatt
    78301 tgcgtctgcg cggcaagctg tacttgctgc tgcaacgtaa tgcgctgcgg gcaccggatc
    78361 aatttgaaat cccgccaaac agagttatcg aactgggtac tcaggtcgaa atctaacgcc
    78421 agacgcctcc tttctccata agggggcgtt tttgttttca tggttaatca ccatgtaaaa
    78481 cgtttcgagg ttgatcacat ttccgtaacg tcacgatggt tttcccaact cagtcaggat
    78541 taaactgcgg gtcagcgaaa cgtttcgctg atggagaaaa aaatgaaaaa aggcaccgtt
    78601 cttaattctg atatttcatc ggtgatctcc cgactgggac ataccgatac gctggtggtg
    78661 tgtgatgctg gtttacccat ccccaaaagt acaacgcgta tcgatatggc attaacccag
    78721 ggtgtacctt cttttatgca ggtgctgggc gtcgtcacaa atgaaatgca ggtcgaggct
    78781 gtcattatcg cggaagagat caaacaacat aatccgcaac tccacgaaac gttgctcact
    78841 caccttgagc agctgcaaca acaccaggga aacaccattg aaattcgtta caccacgcat
    78901 gaacaattca aacaacaaac cgcagaaagt caggcggtaa ttcgcagcgg agaatgttct
    78961 ccgtatgcga atatcattct ctgtgctggc gtgacgttct gaggccgtca tggaagcatt
    79021 acttcagctt aaaggcatcg ataaagcctt tccgggcgta aaagccctct cgggcgcagc
    79081 gttaaatgtc tatccgggcc gcgtgatggc gctggtgggc gaaaacggcg cgggtaaatc
    79141 caccatgatg aaagtgctta ctggtatcta tactcgcgat gccggtacgc ttttatggtt
    79201 ggggaaagaa acgacattta ccgggccgaa atcttcccag gaagccggga ttgggattat
    79261 ccaccaggaa ctgaacctga tcccgcagtt aaccattgcc gaaaacattt tcctcggtcg
    79321 tgagtttgtt aatcgctttg gcaaaattga ctggaaaacc atgtatgccg aagcggataa
    79381 attgctggct aaacttaacc tgcgctttaa aagcgacaaa ctggtgggtg atctttccat
    79441 cggtgaccag caaatggttg aaatcgccaa agtgctgagc tttgagtcga aagtcatcat
    79501 tatggatgaa ccgaccgatg cgctgaccga taccgaaacc gaatccttgt tccgcgtcat
    79561 ccgcgagctg aaattgcaag gccgcggtat tgtctatatc tcccaccgca tgaaagaaat
    79621 cttcgagatt tgcgatgacg ttaccgtttt tcgtgacgga caatttattg ctgagcgtga
    79681 agtggcatca ctgaccgaag attctctgat tgagatgatg gtgggccgca agctggaaga
    79741 tcaatatccg cacctggaca aagcgccggg agatatccgc ctgaaagtcg ataatctctg
    79801 cggacctggc gttaacgatg tctcttttac tttacgcaaa ggcgaaattc ttggcgtctc
    79861 tggtttgatg ggcgctgggc gtaccgaact gatgaaagtg ctctacggcg cactgccgcg
    79921 cacaagcggt tacgtcaccc tggatgggca tgaagtcgtt acccgttcgc cgcaggatgg
    79981 cctggcaaac ggcattgttt atatctccga agaccgtaaa cgtgacggtt tagtgctggg
    80041 catgtcagta aaagagaaca tgtcgctgac cgcgctgcgc tacttcagcc gcgctggcgg
    80101 cagtttgaag catgccgatg aacagcaggc tgtgagtgat ttcattcgtc tgtttaatgt
    80161 gaaaacgcca tcgatggaac aggcaattgg tctgctttcc ggtggcaatc agcaaaaagt
    80221 agcgattgcc cgtggtctga tgacacgccc taaagtgttg atcctcgatg agcctacccg
    80281 tggcgtagat gtcggcgcga aaaaagagat ctatcaactg attaaccagt tcaaagccga
    80341 tggcttgagc atcattctgg tgtcatcgga gatgccagaa gtattaggca tgagcgatcg
    80401 catcatcgtc atgcatgaag ggcatctcag cggggaattt actcgtgagc aggccaccca
    80461 agaagtgtta atggctgccg ctgtgggcaa gcttaatcgc gtgaatcagg agtaaaaaaa
    80521 tgacaaccca gactgtctct ggtcgccgtt atttcacgaa agcgtggctg atggagcaga
    80581 aatcgcttat cgctctgctg gtgctgatcg cgattgtctc gacgttaagc ccgaactttt
    80641 tcaccatcaa taacttattc aatattcttc agcaaacctc ggtgaacgcc attatggcgg
    80701 tcgggatgac gctggtgatc ctgacgtcgg gtatcgactt gtcggtaggt tctctgttgg
    80761 cgctgaccgg cgcagttgct gcatctatcg tcggcattga agtcaatgcg ctggtggctg
    80821 tcgctgccgc tctcgcgtta ggtgccgcaa ttggtgcggt aactggggtg attgtagcga
    80881 aaggtcgcgt ccaggcgttt atcgctacgc tggttatgat gcttttactg cgcggcgtga
    80941 ccatggttta taccaatggt agcccagtga ataccggctt tactgagaac gccgatctgt
    81001 ttggctggtt tggtattggt cgtccgctgg gcgtaccgac gccagtctgg atcatgggga
    81061 ttgtcttcct cgcggcctgg tacatgctgc atcacacgcg tctggggcgt tacatctacg
    81121 cgctgggcgg caacgaagcg gcaacgcgtc tttctggtat caacgtcaat aaaatcaaaa
    81181 tcatcgtcta ttctctttgt ggtctgctgg catcgctggc cgggatcatt gaagtggcgc
    81241 gtctctcctc cgcacaaccc acggcgggga ctggctatga gctggatgct attgctgcgg
    81301 tggttctggg cggtacgagt ctggcgggcg gaaaaggtcg cattgttggg acgttgatcg
    81361 gcgcattaat tcttggcttc cttaataatg gattgaattt gttaggtgtt tcctcctatt
    81421 accagatgat cgtcaaagcg gtggtgattt tgctggcggt gctggtagac aacaaaaagc
    81481 agtaataacg actacaggac atcttgaata tgaacatgaa aaaactggct accctggttt
    81541 ccgctgttgc gctaagcgcc accgtcagtg cgaatgcgat ggcaaaagac accatcgcgc
    81601 tggtggtctc cacgcttaac aacccgttct ttgtatcgct gaaagatggc gcgcagaaag
    81661 aggcggataa acttggctat aacctggtgg tgctggactc ccagaacaac ccggcgaaag
    81721 agctggcgaa cgtgcaggac ttaaccgtcc gcggcaccaa aattctgctg attaacccga
    81781 ccgactccga cgcagtaggt aatgctgtga agatggctaa ccaggcgaac atcccggtta
    81841 tcactcttga ccgccaggca acgaaaggtg aagtggtgag ccacatcgca tctgataacg
    81901 tactgggcgg caaaatcgcc ggtgattaca tcgcgaagaa agcgggtgaa ggtgccaaag
    81961 ttatcgagct gcaaggcatt gccggtacat ccgcagcccg tgaacgtggc gaaggtttcc
    82021 agcaggccgt tgctgctcac aagtttaatg ttcttgccag ccagcctgca gattttgatc
    82081 gcaccaaagg cttgaacgta atgcagaacc tgttgaccgc tcatccggat gttcaggctg
    82141 tattcgcgca gaatgatgaa atggcgcttg gcgcgctgcg cgcactgcaa actgccggta
    82201 aatcggatgt gatggtcgtc ggatttgacg gtacaccgga tggcgaaaaa gcggtgaatg
    82261 atggcaaact agcagcgact atcgctcagc tacccgatca gattggcgcg aaaggcgtcg
    82321 aaaccgcaga taaagtgctg aaaggagaga aagttcaggc taagtatccg gttgatctga
    82381 aactggttgt taagcagtag ttttaatcag gttgtatgac ctgatggtga cataaatacg
    82441 tcatcgacag atgaacgtgt aatataaaga aaagcagggc acgcgccacc ctaacacggt
    82501 ggcgcatttt atggacatcc cgaatatgca aaacgcaggc agcctcgttg ttcttggcag
    82561 cattaatgct gaccacattc ttaatcttca atcttttcct actccaggcg aaaccgtaac
    82621 cggtaaccac tatcaggttg catttggcgg caaaggcgcg aatcaggcgg tggctgctgg
    82681 gcgtagcggt gcgaatatcg cgtttattgc ctgcactggc gatgacagca ttggtgagag
    82741 cgttcgccag cagctcgcca ctgataatat cgatatttct ccggtcagcg tgatcaaagg
    82801 cgaatcaaca ggtgtggcgc tgatttttgt taatggcgaa ggtgagaatg tcatcggtat
    82861 tcatgccggc gctaatgctg ccctttcccc ggcgctggtg gaagcgcaac gtgagcgtat
    82921 tgccaacgcg tcggcattat taatgcagct ggaatcacca ctcgaaagtg tgatggcagc
    82981 ggcgaaaatc gcccatcaaa ataagactat cgttgcgctt aacccggctc cggctcgcga
    83041 acttcctgac gaacttctgg cgctggtgga cattattacg ccaaacgaaa cggaagcaga
    83101 aaagctcacc ggtattcgtg ttgaaaatga tgaagatgca gcgaaggcgg cgcaggtact
    83161 gcatgaaaaa ggtatccgta ctgtactgat tactttagga agtcgtggtg tatgggctag
    83221 cgtgaatggt gaaggtcagc gcgttcctgg attccgggtg caggctgtcg ataccattgc
    83281 tgccggagat acctttaacg gcgcgttaat cacggcgttg ctggaagaaa aaacattgcc
    83341 agaggcgatt cgttttgccc atgcagccgc tgcgattgcc gtaacacgta aaggcgcaca
    83401 accttccgta ccgtggcgtg aagagatcga cgcattttta gacaggcaga ggtgacgctt
    83461 ggctacaatg aaagatgttg cccgcctggc gggcgtttct acctcaacag tttctcacgt
    83521 tatcaataaa gatcgcttcg tcagtgaagc gattacagcc aaagttgaag cggcgattaa
    83581 agaactcaat tacgcgccat cagctctggc gcgtagcctc aaactcaatc aaacacatac
    83641 cattggcatg ttgatcactg ccagtaccaa tcctttctat tcagaactgg tgcgtggcgt
    83701 tgaacgcagc tgcttcgaac gcggttatag tcttgtcctt tgcaataccg aaggcgatga
    83761 acagcggatg aatcgtaatc tggaaacgct gatgcaaaaa cgcgttgatg gcttgctgtt
    83821 actgtgcacc gaaacgcatc agccttcgcg tgaaatcatg caacgttatc cgacagtgcc
    83881 taccgtgatg atggactggg ctccgttcga tggcgacagc gatcttattc aggataactc
    83941 gttgctgggc ggagacttag caacgcaata tctgatcgat aaaggtcata cccgtattgc
    84001 ctgtattacc ggtccgctgg ataaaactcc ggcgcgcctg cggttggaag gttatcgggc
    84061 tgcgatgaaa cgtgcgggtc tcaacattcc tgatggctat gaagtcactg gtgattttga
    84121 atttaacggc gggtttgacg ctatgcgcca actgttatca catccgctgc gtcctcaggc
    84181 cgtctttacc ggaaatgacg ctatggctgt tggcgtttac caggcgttat atcaggcaga
    84241 gttacaggtt ccgcaggata tcgcggtgat tggctatgac gatatcgaac tggcaagctt
    84301 tatgacgcca ccattaacaa ctatacacca accgaaagat gaactggggg agctggcgat
    84361 tgatgtactc atccatcgga taacccagcc gaccctacag caacaacgat tacaacttac
    84421 tccgattctg atggaacgcg gttcggctta gatttacgct gtcttttgat caaattatta
    84481 ccatcggttg ttttcagtag catgaacatt gctgctgaag caacagtaat aatgcccatc
    84541 gtgataaacg tatagtggaa ttgttcgact gtcgttgtgc cttccatccc ttcgtaaacg
    84601 cgaaggacgg ccgcacttac agcaacgcct aaactgatag acagttgctg cgtgaccgcc
    84661 agaacactgt taccgctgct ggcgttgtca tcggtcagat cggcaagtgt gatggtattc
    84721 atcgcggtaa attgcgtcga catagccatc cctaatataa acaacggcaa gatcagcatc
    84781 catatcgcca ttgctggtga ttgcaaagag aactgagcga tcattagccc aataatcacc
    84841 gtgatcccca ctaacgtatg gcgatagccc agacgacgta agacttgggt aaccatcgat
    84901 tttgcaataa tggaacctaa cgctgtcggt gccatcatac agccagcaat aaacgcctga
    84961 tacccaaatc ctacctgtaa catcaatggc ataaggaacg gtacacagcc ggtccccaga
    85021 cgggttgcaa tattgcctac gataccgatc gagaaagtgc gggttttaaa taaatctaat
    85081 gaaattaatg ggtttggcgt gcgtcgcgca tggagaatat agagaagcag taaccagatg
    85141 ctggtgacaa ttaccgtcaa ggcaatccag ctggcgacaa tcttttcccc gaatagctct
    85201 attccgcttg agaagagaac aaggctgagg ccaaacagca aaaagccagt ggtatcgaat
    85261 ctgcgtcgtg cggtggtgaa attgggcata tgtttgcgcg cgtaaagaag gcccgcaata
    85321 cctatgggga tattgattaa aaatatccag tgccaggttg cccaggtgac cagcacgccg
    85381 ccaagaacgg ggcctaaaat tggccccacc agacccggca tggcgacaaa attcaataca
    85441 ggaagaagtt cattacgagg ataagcgcgc agtaaggcca gccgagcaac aggcatcatc
    85501 attgcgccgc ctatcccctg aataacccgg aagacaacca gctgtggtag cgagttggaa
    85561 agtgcgcagg ccagagaacc caacgtgaac agactcacgg caagggtaaa aatgcgacgc
    85621 gtaccgaagc gatcggctag ccatccgctt accggaataa gcatcgccac cgtcagcgta
    85681 taactgatga tggctgattg catcgcgaga ggagaacgat taaggctatg agcgattgcg
    85741 ggtaaggcgg tattcagaat agtggcatca agtgcctgca tgaagaaggc catcgccgcg
    85801 atccacggca aacccgccat actgcgcttc tttttatcgc tcattcaaag tcctgttatc
    85861 gggttatcac ttatctggtg agcgtagcag cgcctgacaa gctttaaatg ccgcgtcgcc
    85921 atcgctttgg ataatcgtat cgacaatcgc ctggtgcaga tccagcttta tcactgtgtc
    85981 gctggtaatt gacgtgaagt aagtgtgata aaccgaatgg aatagcgagg cgaatgaggt
    86041 caaaaacgga ttggcgctca tttcatagat atgctcatgc caggccatat cgacttcgat
    86101 ccagcgttca cggcgaaagt tctcttttaa tgccgccatt tcggccatta acgtattgag
    86161 atgcgccttc tgttccgcgg tgccaaccgt tgctgccagt aggcaagctt gcggctccag
    86221 acagatacgc ataaccagaa agtgatcgat gacctgatga aagttctctt ctgtcatcca
    86281 ccaggtaagc aattcctgat caagaaaatt ccagttcgat tgtggcatga ctcgggtacc
    86341 aattcgcggt cgcggtaaaa ccatcccttt tgccgttaac gttttgaccg cttcgcgtac
    86401 cgctgtacga ctcactccaa attgctcgcc cagctcaatc tcaccaggca aaatggtgcc
    86461 gggttcatat tcacctttta agatccgctg cgccagcttt tcagccagaa catacgaaag
    86521 gtttttctgt gcagctaact gttgtgcgct taaaggcatt actaatcttc ctttttcttt
    86581 ttattcctcc ttagtatgcc accaggaagt gtgattacgg ttgcaaaaac ggcaaattgc
    86641 ttgttttatg gcacattaac ggggcttttg ctgaaaaaat gcgcggtcag aaaattattt
    86701 taaatttcct cttgtcaggc cggaataact ccctataatg cgccaccact gacacggaac
    86761 aacggcaaac acgccgccgg gtcagcggga ttctcctgag aattccggca gagaaagcaa
    86821 aaataaatgc ttgactctgt agcgggagag cgtattatgc acaccccgcg ccgctaagaa
    86881 aaaacgaagc ggcactgctc tttaacaatt tatcagacaa tctgtgtggg cactcgaaga
    86941 tacggattct tgacgtcgca agacgaaaaa tgaataccaa gtctcaagag tgaacacgta
    87001 attcattacg aagtttaatt ctttgagcat caaactttta aattgaagag tttgatcatg
    87061 gctcagattg aacgctggcg gcaggcctaa cacatgcaag tcgaacggta acaggaaaca
    87121 gcttgctgtt tcgctgacga gtggcggacg ggtgagtaat gtctg
//
LOCUS       DAFGPF010000006        79932 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFGPF010000006 DAFGPF010000000
VERSION     DAFGPF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 79932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79932
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.006"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..2523
                     /locus_tag="LSX49_000529"
     CDS             <1..2523
                     /locus_tag="LSX49_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000860751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBL7166989.1"
                     /translation="HDRMTKTFVRFPHAALAALAELLAQKDQKRWRMMLMTMLISQPT
                     LAERVIPWLSTPAVAVLKSCQQQLTQPSNHASADMLPAVLVSPPWLSKKKKSVMPVLD
                     LTPLPLESCCTLTETAEKEIHARHRWHAHQIDIGQKEDIQNYLTRLGFNRWNNGQYMK
                     ASDAVVELWQRGDYSALISEFKTFWHSYQREWQLYMLAALPIEKTAQAWNVLSKEPHV
                     GVEFVMTHLQLAGLQGFIHSFSRYPQEALPVAQYFAAIELAPLIARAFNKLKTLRQDA
                     RIWLLKYPEHAITGLLPAALGKTGEAQDNARAALRMLTENGHQPLLQEIARRYNQPEV
                     TDAVNALLALDPLDNHPTKIPTLPTFYQPSLWTRPLLKANAQSLPDSALLHLGEMLRF
                     PQEEALYPGLLQVKDACTTDSLAEFAWDLFTAWQTAGAPSKESWAFTALGVLGNDDTA
                     RKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNGIAQKLKFKALQERAKEKI
                     ANIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFTVSFDETLKPFVRDASGSR
                     LKDLPKPNKSDDESQANNAVNRYKLLKKDARTVAAQQVARLESAMCLRRRWSPENFQL
                     FLVEHPLVRHLTRRLIWGVYSAENQLLACFRVAEDNSYSTADDDLFTLPEGDISIGIP
                     HVLEISPTDAAAFGQLFADYELLPPFRQLDRNSYALTEAERNASELTRWAGRKCPSGR
                     VMGLANKGWMRGEPQDGGWIGWMIKPLGRWSLIMEIDEGFAVGMSPAELSAEQLLSKL
                     WLWEGKAESYGWGSNSTQEAQFSVLDAITASELINDIEALFE"
     gene            2533..6165
                     /locus_tag="LSX49_000530"
     CDS             2533..6165
                     /locus_tag="LSX49_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBL7166990.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRNWPGEPVPVITENIIQ
                     TLGDELLQKAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSITARTMAALACIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFIVRCYESDPLVVTLQYQNEDYGYGYRSETY
                     NEFDLRLRKHLSLAEESCWQRCADKLIAALPGITKVRRPFIALNLPEKPEIANELVSL
                     ECSQTHFRSKEWLKVVADDPKAVKELARYWSQDIFSDREASYMSHENHFGYAACAALL
                     REQGLAAVPRLAMYAHKEDCGSLLVQINHPQVIRTLLLVADKNKPSLQRVAKYSKNFP
                     HATLAALAELLALKAPPARPGYPIIEDKKLPAQQKARDEYWHTLLQTLMASQPQLAEE
                     VMPCLCTQAQAVVNGYLSASPKLAFESTHSNDLPEILVSPPWRGKKKTALLRLDLVPL
                     ELAPKARWQPGERERLAATESARYFSTGSFTERMERKSGRVVLQELGFGDDVWLFRNY
                     ILPGKLDAARKSLVGQWHYSPRRVEEINNGWHSTEAKSAEQALRSGDVEALINTWEND
                     SYSHYRQEKSVWNLYLLAQLPREMALTFWLRINEKKHLFAGEDYFLSILGLDTLPGLL
                     LAFSHHPKETFPLILNFGATELALPVARVWRRFAAQRDLARQWILQWPEHTATALIPL
                     VFTKPSDNSEAALLALRLLYEQGHGELLQTVANRWQRTDVWPALEQLLKLGPIEIYPA
                     RIPKAPDFWHPGMWSRPRLITNNQPVTDDALEIIGEMLRFTQGGRFYGGLEQLKTFCQ
                     PQTLAAFAWDLFTAWQQAGAPAKDNWAFLALSLFGDETTARDLTTQILAWPQEGKSAR
                     AVSGLNILTLMNNDMALIQLHHISQRAKSRSLRDNAAEFLQVVAENRGLSQEELADRL
                     VPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRLRADDDQLKAPE
                     ALARLKGLKKDATQVSKNLLPRLEAALRITRRWSLADFHSLFVNHPFTRLVTQRLIWG
                     VYPANEPRRLLNAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMAAEMRSEFAQLF
                     ADYEIMPPFRQLARRTVLLTPDESASNSLTRWEGKSATVGQLMGMRYKGWESGYEDAF
                     VYDLGAYRLVLKFSPGFNHYNVDSKALMSFRSLRVYRDNKSVTFAELDVFDLSEALSA
                     PDVIFH"
     gene            6226..6542
                     /locus_tag="LSX49_000531"
                     /pseudo
     CDS             6226..6542
                     /locus_tag="LSX49_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7244..8332
                     /locus_tag="LSX49_000532"
     CDS             7244..8332
                     /locus_tag="LSX49_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416623.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBL7166991.1"
                     /translation="MSPQNNHLQRPPAAVLYAVELAKLKQNDNAPCPPGWQLSLPAAR
                     AFILGDEAQNIRRKVVISPSAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYLGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCIAGTIVKDNEEDRAR
                     LRRYFEQRVATHKEAHWQAYYQARHRLP"
     gene            8343..10622
                     /locus_tag="LSX49_000533"
     CDS             8343..10622
                     /locus_tag="LSX49_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7166992.1"
                     /translation="MSEPLIVGIRHHSPACARLVKSLIESQRPRYVLIEGPADFNDRV
                     DELFLAHQLPVAIYSYCQYQDGAAPGRGAWTPFAEFSPEWQALQAARRIQAQTYFIDL
                     PCWAQSEEEDDSPDTQDESQTLLLRATRMDNSDTLWDHLFEDESQQTALPSTLAHYFA
                     QLRGDSPGDALNRQREAFMARWITWAMQQNNGDVLVVCGGWHAPALAKMWRKCPQEMN
                     KPELSSLADGVTGCYLTPYSEKRLDVLAGYLSGMPAPVWQNWCWQCGLQQAGEQLLKT
                     VLTRLRQHKLPASTADMAAAHLHAMALAQLRGHTLPLRTDWLDAIAGSLIKEALNAPL
                     PWSYRGVIHPDTDPILLTVIDTLAGDGFGKLSPSTPQPPLPKDVTCELERTGISLPAE
                     LTLNRFTPDGLAQSQVLHRLAILEIPGVVRQQGSTLTLAGNGEECWKLTRPLSQHAAL
                     IEAACFGATLQEAARHKLEADMLDAGGIGCITTCLSQAALAGLASFSQQLLEQLTLLI
                     AQENQFAEMGQALEVLYALWRLDEISGMQGAQILQTTLCAAIDRTLWLCESNGRPDEK
                     EFHAHLHSWQALCHILRDLHSGVNLPGVSLSAAVALLERRSQAIHAPALDRGATLGAL
                     MRLEHPNASAEAALTMLAQLSPAQSGEALHGLLALARHQLACQPVFIAGFSSHLNQLS
                     DADFINALPDLRAAMAWLPPRERGTLAHQVLEHYQLTQLPVSALQMLLHCPPQAIAHH
                     QQLEQQALASLQHWGVFHV"
     gene            10615..11751
                     /locus_tag="LSX49_000534"
     CDS             10615..11751
                     /locus_tag="LSX49_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL7166993.1"
                     /translation="MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERYGGLGRSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARRIVHQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSFISLARNFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRYSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSSATPCYDHDTAQALVNVGAQIAAMTPGELASWLAENLQS"
     gene            11748..13751
                     /locus_tag="LSX49_000535"
     CDS             11748..13751
                     /locus_tag="LSX49_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HBL7166994.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHEN
                     GALIATFSDGVRTQLANGQALKEAQCTCGASGMCRHRVMLVLSYQRLCATAQPTEKKE
                     EEWDPAIWLKELANLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRS
                     SIRFARCDCIEGTLCEHVVLAVQAFVEAKTQQAEFTHLIWQMRSEHVTSSDDPFASEE
                     GKTCRQYVQQLSQALWLGGISQPPIHYEAAFSRAQQAAERCNWRWVSESLRQLRASVD
                     AFHARASHYHAGECLRQLAALNSRLNCVQEMARRDSIGEVPPMPWRTVVGAGIAGEAK
                     LDHLRLVSLGMRCWQDIEQYGLRIWFTDPDTGSILHLSRSWQRSEQENSPAATRRLFS
                     FQAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVAL
                     REYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNVLTLS
                     LPASACSPFAVERMAALLQQTDDPVSLVSGFVSFVEGQLTLEPRVMMTKTRAWALDAE
                     TAPVAPLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAIGEAELLANDLTA
                     VGFYRLAHVLGQFRNTESEARVEAMNNGVLLCEQLFPMLQQQG"
     gene            13876..14337
                     /locus_tag="LSX49_000536"
     CDS             13876..14337
                     /locus_tag="LSX49_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HBL7166995.1"
                     /translation="MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAIT
                     YVYKGDKVLKQSSETKIQFASIGATTKEDAARTLEPLSAKYKNIAGVEEKLTYTDTYA
                     QENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK"
     gene            complement(14378..14848)
                     /locus_tag="LSX49_000537"
     CDS             complement(14378..14848)
                     /locus_tag="LSX49_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBL7166996.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPALEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKS"
     gene            complement(14895..15614)
                     /gene="yehT"
                     /locus_tag="LSX49_000538"
     CDS             complement(14895..15614)
                     /gene="yehT"
                     /locus_tag="LSX49_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HBL7166997.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(15611..17296)
                     /gene="btsS"
                     /locus_tag="LSX49_000539"
     CDS             complement(15611..17296)
                     /gene="btsS"
                     /locus_tag="LSX49_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HBL7166998.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            17518..18249
                     /gene="mlrA"
                     /locus_tag="LSX49_000540"
     CDS             17518..18249
                     /gene="mlrA"
                     /locus_tag="LSX49_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HBL7166999.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRT
                     WIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQTLLAILDGVLINYISICLASARKK
                     QGKDALVVGWNIQDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFEGRTLLVWCGD
                     NRTSAQQQQLTSWQEQGHDIFPLGI"
     gene            18309..18416
                     /locus_tag="LSX49_000541"
     CDS             18309..18416
                     /locus_tag="LSX49_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HBL7167000.1"
                     /translation="MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG"
     gene            complement(18397..19128)
                     /gene="yehW"
                     /locus_tag="LSX49_000542"
     CDS             complement(18397..19128)
                     /gene="yehW"
                     /locus_tag="LSX49_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HBL7167001.1"
                     /translation="MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVIGFGLKPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQAFSQHAK"
     gene            complement(19133..20059)
                     /gene="yehX"
                     /locus_tag="LSX49_000543"
     CDS             complement(19133..20059)
                     /gene="yehX"
                     /locus_tag="LSX49_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HBL7167002.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMALLGLEPNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLQGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLAMLTHPANDFVRQFFGRSELGVRLLSLRSVADYVRREERAEGEALEERMTLRDALS
                     LFVARGCEVLPVVNTQGQPCGTLHFQDLLEEA"
     gene            complement(20052..21209)
                     /gene="yehY"
                     /locus_tag="LSX49_000544"
     CDS             complement(20052..21209)
                     /gene="yehY"
                     /locus_tag="LSX49_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HBL7167003.1"
                     /translation="MTYLRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTLWMLVGVGCAWLTACFIPAKKGSIFALILAQFVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGTLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGVQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKRND"
     gene            complement(21216..22133)
                     /gene="osmF"
                     /locus_tag="LSX49_000545"
     CDS             complement(21216..22133)
                     /gene="osmF"
                     /locus_tag="LSX49_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HBL7167004.1"
                     /translation="MPLSKVWAGSLVLLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNVQ
                     QGYEKVKKLDAEQNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTF
                     KLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLKEYPQMAQWLQPVFASLDEKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWTK"
     gene            complement(22323..24620)
                     /gene="bglX"
                     /locus_tag="LSX49_000546"
     CDS             complement(22323..24620)
                     /gene="bglX"
                     /locus_tag="LSX49_000546"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HBL7167005.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSIMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKS
                     GKVTMEELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKAEFELL"
     gene            24816..26531
                     /gene="dld"
                     /locus_tag="LSX49_000547"
     CDS             24816..26531
                     /gene="dld"
                     /locus_tag="LSX49_000547"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HBL7167006.1"
                     /translation="MSSMTTTDNKAFLNELSRLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            complement(26570..27502)
                     /gene="pbpG"
                     /locus_tag="LSX49_000548"
     CDS             complement(26570..27502)
                     /gene="pbpG"
                     /locus_tag="LSX49_000548"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416638.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HBL7167007.1"
                     /translation="MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(27676..28263)
                     /locus_tag="LSX49_000549"
     CDS             complement(27676..28263)
                     /locus_tag="LSX49_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HBL7167008.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            28433..29011
                     /locus_tag="LSX49_000550"
     CDS             28433..29011
                     /locus_tag="LSX49_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBL7167009.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDNQA"
     gene            complement(29141..29902)
                     /locus_tag="LSX49_000551"
     CDS             complement(29141..29902)
                     /locus_tag="LSX49_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7167010.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTA
                     REVVSHGVRAEIVQLDLGNLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDDGDVKPGAEPSIPLRRFGATHEIA
                     SLVVWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(29955..31391)
                     /gene="mdtQ"
                     /locus_tag="LSX49_000552"
     CDS             complement(29955..31391)
                     /gene="mdtQ"
                     /locus_tag="LSX49_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HBL7167011.1"
                     /translation="MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTA
                     LPTALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAVATQD
                     GPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNR
                     AEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIAT
                     DRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLSALTNHQTKALKLNP
                     VALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAV
                     NDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRE
                     RANGLLLQGQWLDASIQLTGALGGGYKR"
     gene            31615..31698
                     /gene="yohP"
                     /locus_tag="LSX49_000553"
     CDS             31615..31698
                     /gene="yohP"
                     /locus_tag="LSX49_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HBL7167012.1"
                     /translation="MKIILWAVLIIFLIGLLVVTGVFKMIF"
     gene            complement(32086..33036)
                     /gene="dusC"
                     /locus_tag="LSX49_000554"
     CDS             complement(32086..33036)
                     /gene="dusC"
                     /locus_tag="LSX49_000554"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HBL7167013.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQQCMAISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIDKLR"
     gene            33275..33673
                     /locus_tag="LSX49_000555"
     CDS             33275..33673
                     /locus_tag="LSX49_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL7167014.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            33670..34365
                     /locus_tag="LSX49_000556"
     CDS             33670..34365
                     /locus_tag="LSX49_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HBL7167015.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            34495..35379
                     /gene="cdd"
                     /locus_tag="LSX49_000557"
     CDS             34495..35379
                     /gene="cdd"
                     /locus_tag="LSX49_000557"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL7167016.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDAT
                     SATLKALGCHNIDRVLLA"
     gene            35529..36248
                     /gene="sanA"
                     /locus_tag="LSX49_000558"
     CDS             35529..36248
                     /gene="sanA"
                     /locus_tag="LSX49_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HBL7167017.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            36251..36490
                     /locus_tag="LSX49_000559"
     CDS             36251..36490
                     /locus_tag="LSX49_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HBL7167018.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR"
     gene            36684..37922
                     /gene="preT"
                     /locus_tag="LSX49_000560"
     CDS             36684..37922
                     /gene="preT"
                     /locus_tag="LSX49_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /protein_id="HBL7167019.1"
                     /translation="MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDAPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPG
                     GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVG
                     LSSGSGLSLFEHSDVEIAVDFLQRARQAQGDISIQQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFTSARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELT
                     IAADKIILAVGQHAELAAFSALEPQRNTIETQHYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAGAIHHYLEGACSC"
     gene            37916..39151
                     /gene="preA"
                     /locus_tag="LSX49_000561"
     CDS             37916..39151
                     /gene="preA"
                     /locus_tag="LSX49_000561"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HBL7167020.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGS
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANHNIVPAEDLDRSYI
                     VYPHINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IDLGEVKFKKGEKEHPVTL"
     gene            complement(39394..40404)
                     /gene="mglC"
                     /locus_tag="LSX49_000562"
     CDS             complement(39394..40404)
                     /gene="mglC"
                     /locus_tag="LSX49_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HBL7167021.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFIALGSFRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(40420..41940)
                     /gene="mglA"
                     /locus_tag="LSX49_000563"
     CDS             complement(40420..41940)
                     /gene="mglA"
                     /locus_tag="LSX49_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
                     /protein_id="HBL7167022.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANE
                     AINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     MRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA
                     ELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQSEILRLASLHL"
     gene            complement(42001..42999)
                     /gene="mglB"
                     /locus_tag="LSX49_000564"
     CDS             complement(42001..42999)
                     /gene="mglB"
                     /locus_tag="LSX49_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HBL7167023.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK"
     gene            complement(43279..44319)
                     /gene="galS"
                     /locus_tag="LSX49_000565"
     CDS             complement(43279..44319)
                     /gene="galS"
                     /locus_tag="LSX49_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HBL7167024.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGTGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMAKLATELALQGAADNIDPRASHCFMPTLVRRHSVATRQN
                     AAAITNSTNQAM"
     gene            complement(44461..45618)
                     /locus_tag="LSX49_000566"
     CDS             complement(44461..45618)
                     /locus_tag="LSX49_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HBL7167025.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     QDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVEAINNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVIINLPAIALQWQLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLSLFMQFDR
                     LELLAFVIPVWLANIFFSVIWLRYFRQGPVEWLWRQLTLRAAGPTISKTSR"
     gene            complement(45635..46303)
                     /gene="folE"
                     /locus_tag="LSX49_000567"
     CDS             complement(45635..46303)
                     /gene="folE"
                     /locus_tag="LSX49_000567"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBL7167026.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            46561..47397
                     /gene="yeiG"
                     /locus_tag="LSX49_000568"
     CDS             46561..47397
                     /gene="yeiG"
                     /locus_tag="LSX49_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HBL7167027.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEQVANDDGYDLGQGAGF
                     YLNATQPPWATHYQMYDYLRDELPALIQSQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSTYLGEDKNAWLEWDSCALMYASNAQDAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYL
                     LK"
     gene            complement(47429..49420)
                     /gene="cirA"
                     /locus_tag="LSX49_000569"
     CDS             complement(47429..49420)
                     /gene="cirA"
                     /locus_tag="LSX49_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HBL7167028.1"
                     /translation="MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNL
                     KDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     VDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWSGTVTVDTTVQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNS
                     TTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQN
                     YSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGKYTLPLTAINQFLTV
                     GGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGE
                     HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPE
                     TSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFET
                     GANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLS
                     DLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVT
                     KDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF"
     gene            complement(49712..51181)
                     /gene="lysP"
                     /locus_tag="LSX49_000570"
     CDS             complement(49712..51181)
                     /gene="lysP"
                     /locus_tag="LSX49_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HBL7167029.1"
                     /translation="MGSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            complement(51386..52267)
                     /locus_tag="LSX49_000571"
     CDS             complement(51386..52267)
                     /locus_tag="LSX49_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7167030.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNY
                     ILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
                     DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLS
                     NALRRFLDYCDPANVPR"
     gene            52366..53415
                     /locus_tag="LSX49_000572"
     CDS             52366..53415
                     /locus_tag="LSX49_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HBL7167031.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGTNSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
     gene            53489..54346
                     /gene="nfo"
                     /locus_tag="LSX49_000573"
     CDS             53489..54346
                     /gene="nfo"
                     /locus_tag="LSX49_000573"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBL7167032.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            54350..55438
                     /locus_tag="LSX49_000574"
     CDS             54350..55438
                     /locus_tag="LSX49_000574"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL7167033.1"
                     /translation="MNDREKQILKILRRNPLIQQNEIADILQISRSRVAAHIMDLMRK
                     GLIKGKGYILTEQDYCVVVGAINMDIRGMADIRYPQAASHPGSVHCSAGGVGRNIAHN
                     LALLGRDVHLISAIGNDFYGETLLEETRRAGVNVSNCIRLHGHSTATYLAIANKQEET
                     ILAINDTHILQQLTPQLLNTSRDLIRHAGVVLADCNLTPEALEWVFTIADEIPMFVDT
                     VSEFKANKVKNWYSRIHTLKPTQNELEILWGQPIKDDNDRIRAVNSLHQQGVKRIFVY
                     LKDESVFCSDKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGYSFRDSARFAIA
                     CAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(55706..56647)
                     /gene="rihB"
                     /locus_tag="LSX49_000575"
     CDS             complement(55706..56647)
                     /gene="rihB"
                     /locus_tag="LSX49_000575"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HBL7167034.1"
                     /translation="MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAENT
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            56777..57475
                     /gene="yeiL"
                     /locus_tag="LSX49_000576"
     CDS             56777..57475
                     /gene="yeiL"
                     /locus_tag="LSX49_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HBL7167035.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            complement(57542..58792)
                     /locus_tag="LSX49_000577"
     CDS             complement(57542..58792)
                     /locus_tag="LSX49_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL7167036.1"
                     /translation="MDIMRSVVGMVVLLAIAFVLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSIIEAAANGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFANVSLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTSGTLDVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(58886..59824)
                     /gene="psuG"
                     /locus_tag="LSX49_000578"
     CDS             complement(58886..59824)
                     /gene="psuG"
                     /locus_tag="LSX49_000578"
                     /EC_number="4.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HBL7167037.1"
                     /translation="MSELTLSPELLQISAEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSAREIARA
                     MAVKWQTGLNGGLVVANPIPEQFAMPEETINAAIDQAVAEAEEQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLVG"
     gene            complement(59812..60753)
                     /locus_tag="LSX49_000579"
     CDS             complement(59812..60753)
                     /locus_tag="LSX49_000579"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HBL7167038.1"
                     /translation="MREKDYIVIIGSANIDVAGYSHHPLNYADSNPGKIKFTPGGVGR
                     NIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMSISDCISAEFLAQHQEFIRGAKVIVADCNLSEEALVWVLENSGETP
                     VFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFIDSV
                     RFAQGCSSMALACEYTNNPELSIANVTSLVENTECLN"
     gene            complement(61209..62900)
                     /gene="fruA"
                     /locus_tag="LSX49_000580"
     CDS             complement(61209..62900)
                     /gene="fruA"
                     /locus_tag="LSX49_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HBL7167039.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDFIPNDSALNGKNVWLGDISRAVAHPELFLSEAKGHAKPYTAPVAATAPVAASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATTE
                     GKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILDGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPETQIVEKNA"
     gene            complement(62917..63855)
                     /gene="fruK"
                     /locus_tag="LSX49_000581"
     CDS             complement(62917..63855)
                     /gene="fruK"
                     /locus_tag="LSX49_000581"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL7167040.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            complement(63855..64985)
                     /gene="fruB"
                     /locus_tag="LSX49_000582"
     CDS             complement(63855..64985)
                     /gene="fruB"
                     /locus_tag="LSX49_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HBL7167041.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            65353..66534
                     /gene="setB"
                     /locus_tag="LSX49_000583"
     CDS             65353..66534
                     /gene="setB"
                     /locus_tag="LSX49_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HBL7167042.1"
                     /translation="MHNSPTVTSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTVEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKD
                     V"
     gene            complement(66531..66785)
                     /locus_tag="LSX49_000584"
     CDS             complement(66531..66785)
                     /locus_tag="LSX49_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBL7167043.1"
                     /translation="MECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMIWLIDLEMLTAP"
     gene            66940..67512
                     /gene="yeiP"
                     /locus_tag="LSX49_000585"
     CDS             66940..67512
                     /gene="yeiP"
                     /locus_tag="LSX49_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HBL7167044.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            67735..69201
                     /locus_tag="LSX49_000586"
     CDS             67735..69201
                     /locus_tag="LSX49_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL7167045.1"
                     /translation="MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLT
                     DRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHECLN
                     AKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHS
                     APGILVEALKRRRERGHTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHV
                     SFPGTMVDRIVPAATNESLAEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVA
                     GVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDE
                     QAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRE
                     TDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLRE
                     IFGDDLPDNPHFVQVIEQAWQQIAQFGAHQALLNTLKI"
     gene            69319..70305
                     /gene="yeiR"
                     /locus_tag="LSX49_000587"
     CDS             69319..70305
                     /gene="yeiR"
                     /locus_tag="LSX49_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding GTPase YeiR"
                     /protein_id="HBL7167046.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRATPE
                     SEQALERWWQQNGGDRQLIHSEHGKIDGHLLDLPRRNLAELPASAAHSHQHSVKKGLA
                     ALSLPEHQRWRRSLNSGQGHQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            70344..71057
                     /gene="lpxT"
                     /locus_tag="LSX49_000588"
     CDS             70344..71057
                     /gene="lpxT"
                     /locus_tag="LSX49_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HBL7167047.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPINHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIIGLVMLLTA
                     VVLNQLGQALIPVKRASPTLTFTNINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            71469..72035
                     /gene="mepS"
                     /locus_tag="LSX49_000589"
     CDS             71469..72035
                     /gene="mepS"
                     /locus_tag="LSX49_000589"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HBL7167048.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            72216..73772
                     /locus_tag="LSX49_000590"
     CDS             72216..73772
                     /locus_tag="LSX49_000590"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HBL7167049.1"
                     /translation="MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGLALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVVYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAEAQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPAHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEREATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTET
                     ITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVR
                     WLKKPYTPQW"
     gene            73854..75668
                     /locus_tag="LSX49_000591"
     CDS             73854..75668
                     /locus_tag="LSX49_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL7167050.1"
                     /translation="MIVRILLLFIALFTFGAQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKISDPLATPPLASGPYRITSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYNTWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPPEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPVYSLGIDTWWYDVNKATKLPSARQQGE"
     gene            75669..76763
                     /locus_tag="LSX49_000592"
     CDS             75669..76763
                     /locus_tag="LSX49_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HBL7167051.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNAGVLPGAGGEGVRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            76763..77788
                     /locus_tag="LSX49_000593"
     CDS             76763..77788
                     /locus_tag="LSX49_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7167052.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLLLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            77790..79379
                     /gene="yejF"
                     /locus_tag="LSX49_000594"
     CDS             77790..79379
                     /gene="yejF"
                     /locus_tag="LSX49_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HBL7167053.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVVNDVSLHIEAGETLALVGES
                     GSGKSVTALSILRLLPCPPVEYLSGDIRFHGESLLHASDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMQNGRCVEKNNAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSHGSIVFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSAAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG
                     PCARVFAAPQQEYTRQLLALS"
     gene            complement(79383..79727)
                     /locus_tag="LSX49_000595"
     CDS             complement(79383..79727)
                     /locus_tag="LSX49_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167054.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
BASE COUNT        19585 a        20969 c        19850 g        19528 t
ORIGIN      
        1 cacgatcgca tgacaaagac tttcgttcgc tttccacatg cagcgctggc ggcattagca
       61 gaacttctgg cacaaaaaga tcaaaagcgt tggcgcatga tgctaatgac aatgcttatc
      121 tcacaaccaa cattagcaga gcgagtaatc ccctggctct caacacccgc agttgccgta
      181 ctgaaatcat gccagcaaca actgacacag ccctcaaacc atgccagcgc tgatatgctg
      241 cctgccgtat tagtctcacc gccctggctt tcgaaaaaga aaaaatctgt aatgccggta
      301 ttggatttaa cgccattacc gctggagtca tgctgcacat tgaccgagac ggcagaaaaa
      361 gagattcatg caaggcatcg ctggcacgca catcaaatag acatcggcca aaaagaggat
      421 attcagaact acctgacacg tctgggtttc aatcgctgga ataatggcca gtatatgaaa
      481 gcgtctgatg ctgttgtaga actctggcag aggggagatt attctgcgct aatcagcgaa
      541 tttaaaacct tctggcactc ctatcaacgg gaatggcagc tttacatgtt agccgccctg
      601 cctatcgaaa aaacagcgca ggcgtggaat gtcctcagta aagagccaca cgtcggtgtc
      661 gagtttgtca tgacgcacct gcaactcgct gggttacagg gttttattca ctccttttca
      721 cgctatccac aagaagctct gcctgtagca caatattttg cggctatcga attagcgcca
      781 ctgatcgccc gcgccttcaa caaactcaaa acattacgac aagacgcccg tatctggctg
      841 ctgaaatacc cggaacacgc cattaccggc ctgctgcctg cagcgctcgg caaaaccggt
      901 gaagcacagg acaacgcccg tgctgccttg cgtatgctta ccgaaaacgg tcatcagcca
      961 ttgctgcaag aaatcgcccg gcgttataac cagccggaag taaccgatgc ggtgaacgct
     1021 ctacttgcgc tcgatccctt agataatcac ccgacaaaaa tccccactct tccgaccttt
     1081 tatcagccat cgctctggac gcgcccgtta ttaaaagcaa acgcccaatc actgcctgat
     1141 agcgcactcc tccacctcgg tgaaatgctc cgcttccctc aggaagaggc actgtatcca
     1201 ggattattgc aggtgaaaga tgcctgtacc accgactcac tggctgaatt tgcctgggat
     1261 ctgtttaccg cctggcagac cgctggcgcg ccgtcgaaag agagttgggc gttcactgcg
     1321 ttaggcgttc tcggtaacga tgacaccgcc cgcaaactga cgccattaat ccgtgcctgg
     1381 cctggcgaat cccagcataa acgtgccacc gttgggttgg atatcctcgc cgctatcggt
     1441 agtgatatcg ccctgatgca gcttaacggc atcgcccaga aactgaaatt caaagcatta
     1501 caggagcggg caaaagaaaa aatagccaac attgccgaga gccgcgaact cacggtggcg
     1561 gagcttgaag atcggttagc accggatctc ggtctggatg ataacggttc gttgctgctg
     1621 gatttcggcc cacgccagtt caccgtcagc tttgatgaaa ccttaaaacc gtttgtgcgt
     1681 gacgcttccg gcagtcgtct gaaagacctg cccaaaccaa acaaaagcga tgatgaatca
     1741 caggcgaaca atgctgttaa ccgctacaaa ttgctgaaaa aagatgcgcg taccgtcgcc
     1801 gcccagcagg tagcaaggct ggaatccgcc atgtgcctgc gtcgccgctg gtcaccggaa
     1861 aactttcagc tcttcctggt tgagcatccg ctggtccgcc acttaacccg ccgtctgatt
     1921 tggggcgttt atagcgccga aaaccagcta ctggcttgct ttcgcgtagc ggaagataac
     1981 agctacagca ccgctgacga tgatcttttc accctgccgg aaggcgatat ctctattggt
     2041 attcctcacg ttctggaaat atcaccgacg gatgctgccg ccttcgggca gctttttgcc
     2101 gactacgaac tgttaccacc gttccgccag cttgatcgta acagttacgc gctgacagaa
     2161 gccgagcgca atgccagcga actgacacgc tgggcaggca gaaaatgccc gagtggtcgg
     2221 gtaatggggc tggcaaataa aggctggatg cgtggtgaac cgcaggacgg tggctggatc
     2281 ggctggatga tcaaacctct gggccgctgg tcgttaatca tggaaatcga tgaaggtttt
     2341 gcggtcggca tgtcgccagc cgaactcagt gccgagcaac tcttaagcaa gctgtggcta
     2401 tgggaaggca aagcggaaag ctatggctgg gggagtaatt caacacagga agcgcagttc
     2461 tccgtactcg atgccatcac cgccagcgag ctaattaacg atattgaagc cctgtttgaa
     2521 taaggaaaga gcatggacaa ggaattaccg tggctggcgg ataacgccca actggaactg
     2581 aaatataaaa aaggcaaaac accactcagc catcgcaatt ggccaggcga accggtacct
     2641 gttatcactg aaaacatcat tcagacactg ggtgatgaat tgctacaaaa agcagagaag
     2701 aaaaaaaaca ttgtctggcg ttatgaaaac ttttcactgg agtggcagtc cgccatcacg
     2761 caggccatca acttgatcgg cgaacacaaa ccctcaatca cggcccggac aatggcggcg
     2821 ctagcctgta tcgcgcaaaa tgatagccaa cagttgctcg acgaaatcgt ccaacaagag
     2881 gggctggaat atgcaactga ggtggtgatt gcacgccagt ttattgtacg gtgttatgag
     2941 agtgatcctc tggtagtaac attgcaatat cagaacgagg actatggcta tggttatcgc
     3001 tcagaaacct ataacgaatt cgatctccga ttgcgtaagc atctctctct ggcagaggaa
     3061 agctgctggc agcgttgcgc cgacaaactc attgccgcac tgccaggaat aaccaaagtt
     3121 cgccgccctt ttattgcgct gaacctcccg gaaaaacccg aaatcgccaa cgagctggta
     3181 agccttgaat gttcgcaaac tcattttcgc tcaaaagagt ggttaaaagt tgttgctgat
     3241 gaccctaagg cggtgaaaga actcgcacgc tactggagcc aggatatatt tagcgatcga
     3301 gaagccagct acatgtcgca tgaaaaccac ttcggctacg cggcctgcgc tgcccttttg
     3361 cgcgaacaag gactggcagc cgttccgcgc ctcgcgatgt atgcacataa agaagattgc
     3421 ggcagtctgc tggtacaaat taaccatccg caagtcatcc gcaccttgct actggtggct
     3481 gataaaaaca aacccagcct gcaacgtgtg gctaaataca gtaaaaactt cccccatgcg
     3541 acgctcgccg cactggcaga gctgctggcg ttaaaagccc cccctgcgcg ccctggttat
     3601 cccatcatcg aagacaaaaa gctgcctgca cagcaaaaag cacgtgatga atactggcat
     3661 acgctgttac aaacgctgat ggcatcgcag ccacaactgg cagaagaggt gatgccgtgc
     3721 ttatgtacac aagcccaggc agtggtgaat ggttatttat cggcatcgcc aaaacttgct
     3781 ttcgagagta ctcatagcaa cgacctgcca gaaatacttg tttctccacc gtggcgaggt
     3841 aagaaaaaaa cggcattgct gcgccttgat ttagtgcctc ttgaattagc gcccaaagcc
     3901 cgctggcaac caggcgaacg agagagactt gccgccacag agtctgcccg ttatttcagc
     3961 acgggatctt ttacggaacg catggaacga aaaagtggtc gagttgtact acaggagcta
     4021 ggttttgggg atgatgtatg gctgttccgg aattatatac tgcccggcaa actggatgcg
     4081 gcgcgcaaat cattagtggg tcagtggcat tactccccgc gcagagtaga ggaaatcaac
     4141 aatggctggc actccacgga agcaaaatca gccgaacagg cgcttcgttc cggcgacgtt
     4201 gaagcgttaa ttaacacctg ggaaaatgat agctactcgc attatcgtca ggaaaagagt
     4261 gtctggaacc tgtatttatt ggcgcagttg ccacgtgaga tggctttgac tttctggctg
     4321 cgtatcaatg agaaaaagca tctattcgcg ggtgaggact attttctcag tatcctcggg
     4381 ttggatacat tacctggcct gttattggct ttttcacatc atccaaaaga aacatttccg
     4441 ttaattttaa atttcggcgc aacagaactg gccctgcccg ttgcccgcgt ctggcgacgt
     4501 ttcgcggcgc agcgtgatct ggctcgccag tggattttac aatggccgga acatacggct
     4561 actgcactta tccctcttgt ctttacaaaa cccagcgata atagcgaagc tgcattactt
     4621 gccctgcgtt tactgtatga acaagggcat ggcgaattac tgcaaaccgt ggcaaaccgc
     4681 tggcagcgta cagatgtatg gcctgccctg gagcaattac ttaaactggg tccaatagaa
     4741 atttacccgg cacgtattcc aaaagctcct gatttctggc atccgggaat gtggtccagg
     4801 ccgcgcctta tcactaataa tcagcctgtt accgatgacg ctctggaaat tatcggcgaa
     4861 atgctgcgct ttacccaggg cggacgtttt tatggcggac tggaacagct gaaaacgttt
     4921 tgccagccgc aaacgctggc agcttttgcc tgggatcttt tcaccgcgtg gcaacaagct
     4981 ggtgcccccg caaaagacaa ctgggcattt ctggcgttaa gtctctttgg tgacgaaacc
     5041 acggcacgag atctgacgac acagatcctc gcctggccac aagaaggcaa atctgcccgt
     5101 gctgtcagtg gcctgaacat ccttaccctg atgaataatg atatggcgct gatacagctg
     5161 caccatatat cccaacgggc gaaatcccgc tccttacgtg ataacgcggc ggaatttctt
     5221 caggtggtcg cagaaaatcg cgggctaagc caggaagagt tagcggacag attagtccca
     5281 acattgggcc ttgatgatcc gcaggcgttg agttttgatt ttggtccccg gcagtttacc
     5341 gttcgcttcg atgaaaacct caacccggtt atctttgatc agcaaaacgt tcgccagaaa
     5401 agtgttcccc ggttgcgcgc cgatgacgat caactgaaag cgcccgaggc actggcccga
     5461 ctaaaagggc taaaaaaaga tgccactcag gtgagcaaaa acctgctccc acgtcttgaa
     5521 gcagccctac gtatcacccg ccgctggtcg ctggcagatt ttcattctct gtttgttaat
     5581 catcccttta cccgcctggt tacccagcga ttaatatggg gggtttatcc ggcaaatgaa
     5641 ccgcgtcgtt tactcaacgc ctttcgtgtg gccgcagagg gggagttctg caatgcacaa
     5701 gatgagccca ttgacctgcc tgcggatgct ctgattggca ttgcccaccc gttagaaatg
     5761 gcagcagaaa tgcgcagtga atttgcacag ctttttgccg attacgaaat tatgccgcct
     5821 tttcgccagt tggcgcggcg cacggtgctg ctcacacctg acgagtcagc cagtaacagc
     5881 ctgactcgct gggaaggtaa atccgctacc gttgggcaac ttatgggaat gcgatacaaa
     5941 ggctgggagt caggctatga ggacgcattt gtctatgact taggtgcgta ccggctggtc
     6001 cttaagtttt cacccggttt taaccactac aatgttgata gcaaagcgct aatgagcttc
     6061 cgttctcttc gggtttaccg tgacaataaa tccgtcactt ttgccgaact tgatgtgttt
     6121 gatttgagtg aggcattaag cgcacctgac gtcattttcc attaaaacac agcgggcagt
     6181 gatgcaactg cccgttatca acacgaccta ccagcggggg aagcgatgat cgtgcaaaaa
     6241 gagctggttg ctatttacga ttatgagatc cctgtacctg aagagccgtt ttccttcaga
     6301 cttgaaatcc ataaatgctc tgaattattt acaggttccg tctatcgact ggagcgattc
     6361 cggctacatc caacatttca tcaacgtgat cgagaagatg ccgaccacta ataaatgatg
     6421 cgttgattta tataagagat gagtttattg atgagcggaa attacgaggt gaatcacatg
     6481 aaacagtaat agcaattttt aattgtgaac tacagaatat attcaaccaa gaaatagaat
     6541 aatatactct agataattca agtcgcagga aggcgataag cgagtgagtc cccaggagct
     6601 tactaaagta agtgacaggg gtgaacggac gcagtcgcag cacatgcaac ttgaagtatg
     6661 gcgagtatag ctttattaaa gggggaaacg gtattccccc ttagatgcgt ttcaatttgc
     6721 ccgttacttc aacaaatcaa tcaaccgtaa cagagccact aatagctcca gtacagcaat
     6781 gagcacggtt aacttttgtg tcagcgtgtc catccgctct ccttttaagg agcgcaacac
     6841 cagcacctta cccttacact gcctgtcgat actggtttac gtatgttgga ccacgatgtt
     6901 gcactccgga tcaggcacca cctgcagcac cacccgtccg gtagccagga cttgaaattg
     6961 gttcgatccg gcgcaacctc ccaacagtca ggattataaa tctcattatc ttaattgcaa
     7021 cggggtccag cggtggttat aattcgttcg ttggaacacg atgttgcaca ggctgcggtg
     7081 ttaggcctga aagtaataaa taaaagaacc tgcctcacca gcaggttttt ttattttttg
     7141 cgatctgctt tccagatatt ttccgctcaa acaactaatg cgccaaacat ttattgcgcg
     7201 taaaatatcg tttatttcat taatacattt cagggatgaa tatatgtcac cgcagaataa
     7261 tcacctgcag cgtccgcctg ctgctgtgtt atacgccgtt gaactggcaa aattaaaaca
     7321 aaatgataac gcaccttgcc cgcccggttg gcagttaagt ttgcctgcgg cccgtgcttt
     7381 tattcttggc gacgaagcgc aaaatattcg ccgtaaagtg gtgattagtc cctctgctgt
     7441 cgaacgcatg ttagtcactc ttgccaccgg gcgcggtttg atgttggtgg gggaaccggg
     7501 taccgcaaaa tctctcctgt ctgaattact ggcaaccgct attagcggcg atgccgggtt
     7561 aaccatccag ggcggcgcat ctaccaccga agatcaaatc aagtacggct ggaactacgc
     7621 cctgcttatc aatcatggtc cgtcaacgga agcgctggtc cctgccccgc tttacctggg
     7681 aatgcgcgac ggcaaaatcg tccgttttga agagataacg cgtactccac tggaagtaca
     7741 agactgttta ttaggtatgc tttctgacag ggttatgacg gtgccggaac tcactggtga
     7801 agccagtcaa ctctatgctc gggaaggctt taatattatt gccactgcca atacgcgcga
     7861 tcgcggcgtc aatgaaatga gtgccgcgct aaagcgtcgc ttcgattttg aaactgtctt
     7921 tccgattatg gatttcgccc aggagctgga gcttgtcgcc agtgcttcgg cgcgtttgct
     7981 ggcccatagc ggcattccgc ataaagtgcc tgacgcggta ctggagttac tggtccgcac
     8041 ctttcgcgat ctgcgtgcca acggcgaaaa gaaaacgtca atggatacac tgacagcgat
     8101 tatgtccacc gctgaagccg tgaacgtggc ccacgcggtg ggcgtccgcg cctggttttt
     8161 agcgaatcga gcaggtgagc cagccgatct ggtggactgt attgccggaa ccatcgtcaa
     8221 agataacgaa gaagaccgcg cgcgcctgcg ccgttacttc gaacaacgtg ttgccacaca
     8281 taaagaagct cactggcagg cttattatca agctcgccac cgcctgccgt gaggaaagat
     8341 gcatgagcga gccgttaatt gtcggcatcc ggcatcatag cccggcctgc gcccggctgg
     8401 tgaaatcgtt aatcgaaagc cagcggccac gatacgtatt gattgaaggc ccggctgatt
     8461 ttaatgaccg ggtagacgaa ctgtttttag cccaccagct tccggtagct atttacagtt
     8521 attgccagta tcaggacggt gcggcccccg ggcgtggtgc ctggacgcca tttgctgaat
     8581 tttcgccgga gtggcaggcg ctacaagccg cacgtcgtat tcaggcacaa acttacttca
     8641 tcgatttgcc ttgctgggcg cagagtgaag aagaggacga ttcgcctgat acacaagatg
     8701 aaagccagac cttactgctg cgtgccaccc gcatggataa cagcgatacc ctgtgggatc
     8761 acttattcga agatgaaagc cagcaaactg cattaccctc tacgctggcg cactattttg
     8821 cccaactgcg gggcgattcc cccggagatg ctctcaatcg tcagcgcgaa gcctttatgg
     8881 ctcgctggat tacatgggcg atgcagcaaa acaatggcga cgtgttagtc gtctgcggcg
     8941 gctggcacgc tcctgcactg gcaaaaatgt ggcgcaaatg cccgcaggaa atgaacaagc
     9001 cagaattgtc ctcgctggca gatggcgtta caggttgtta tctcacaccc tacagtgaaa
     9061 agcgccttga tgtgctggca ggataccttt ccggaatgcc tgccccggtc tggcaaaact
     9121 ggtgctggca gtgtggctta cagcaggcag gtgaacaact gctgaaaacg gttcttaccc
     9181 gtttgcgcca gcacaaattg cccgcttcta ccgctgatat ggctgctgct catctgcatg
     9241 cgatggcact ggcacagttg cgcggccata cactacctct acgcactgac tggctggatg
     9301 ccatagctgg ctcgctgatt aaagaagccc tgaatgcgcc gttgccgtgg agctatcgcg
     9361 gagttattca tcccgatacc gatccgattt tgctaacggt gatagacaca ttagcgggtg
     9421 acggattcgg taaactttcc ccttctacgc cacaaccgcc tctgccaaaa gatgtcacct
     9481 gcgaactgga acgtaccgga atctctcttc cggcggagct taccttaaat cgctttaccc
     9541 ccgatggact ggcgcaaagt caggtgttac atcggttggc aatactggag atcccagggg
     9601 ttgtgcgcca gcagggaagt acgctgacac ttgcaggcaa cggtgaagaa tgctggaaat
     9661 taacccgccc gcttagccag catgcggcat tgattgaggc cgcctgcttt ggtgccacac
     9721 tccaggaagc cgcacgccat aaattagaag ccgatatgct ggacgcgggt ggaatcggct
     9781 gtatcaccac atgtcttagc caggcagcgt tagcgggtct ggcgtctttc agtcagcaat
     9841 tactggaaca actcacatta ttaattgccc aggaaaatca attcgccgaa atgggccagg
     9901 cgctggaagt gctatatgcc ttatggcggc tggatgaaat tagcggtatg caaggcgcgc
     9961 agatattaca aacgacatta tgcgcggcca tcgatcgcac gctgtggcta tgtgaatcca
    10021 acggcagacc ggatgaaaag gagtttcacg ctcacctgca tagctggcag gcgctttgcc
    10081 atatcctgcg cgatctacat agcggcgtta atttacccgg cgtttcgctt tctgcggcgg
    10141 tagccttact ggagcgccgc agtcaggcga ttcatgcccc ggcgctggat cgcggcgcga
    10201 ctcttggcgc actgatgcgt ctggaacatc ccaacgccag tgccgaagcg gcgctgacga
    10261 tgctggcgca gttatccccg gcacaatccg gcgaggcgct gcacggtttg ctggcattag
    10321 cccgtcatca actggcctgt cagccggtat ttatcgccgg tttcagcagt catttaaatc
    10381 aactgagtga tgccgatttt atcaatgccc tgcccgattt acgcgcggcg atggcctggc
    10441 taccaccacg agaacgcggg acgctggcgc atcaggtgct tgagcattac cagctcacac
    10501 agcttcccgt ttcagcgctg caaatgctgt tgcattgtcc accacaagcc attgcacatc
    10561 atcaacaact cgaacagcag gcactggcat cgctgcaaca ctggggagtt ttccatgtct
    10621 gaactgaacg atcttctgac cacccgtgag ctacaacgct ggcgattaat tcttggcgaa
    10681 gcggcagaaa cgaccctttg tgggctggat gacaacgccc ggcagataga ccacgcgctg
    10741 gagtggctgt atgggcgcga tcctgaacgg ctccagcgtg gtgaacgtta cggtggatta
    10801 ggtcgttcaa atctcaccac ccctgagtgg attaacagca ttcacacgct gtttccgcaa
    10861 caggtgattg agcggctgga aagcgatgcc gtgctgcgct acggcattga agatgtggtg
    10921 acgaatctcg acgtgctgga acgtatgcag ccttctgaaa gcctgctacg cgccgttttg
    10981 cacaccaaac atctgatgaa tcccgaagta ctggctgccg cccgccggat agtgcaccag
    11041 gttgtggaag aaattatggc tcgactggca aaggaagttc gtcaggcttt ttctggagta
    11101 cgcgatcgcc gtcgccgctc atttatttca ctggcgcgaa actttgattt caaaagtact
    11161 ctgcgcgcca acctgcaaca ctggcacccg caacacggca agttgtatat cgaatccccc
    11221 cgctttaaca gccgcataaa acgctatagc gaacaatggc aactggtcct actggttgat
    11281 caaagcggat cgatggttga ttcggtgatc cactccgcag tgatggcggc ctgtttatgg
    11341 cagttacccg gcattcgtac ccatctggtc gcttttgaca ccagcgtggt tgatctcacg
    11401 gcagacgttg ccgatccggt agagctatta atgaaagtgc aattaggcgg cgggaccaat
    11461 atcgccagtg ctgtggaata tggtcggcaa cttattgaac aaccagcgaa aagcgtcatt
    11521 atcctcgtga gcgattttta cgaagggggg tcatcatcat tgctgacgca tcaggtgaaa
    11581 aagtgtgtcc agagcggcat caaagtgctg ggactggcgg cgctcgatag cagcgcaaca
    11641 ccttgctatg accacgatac ggcccaggcg ctggttaatg tcggcgcaca aatagccgca
    11701 atgacaccgg gcgagctggc ttcctggctt gcggagaatc ttcagtcatg aattcactac
    11761 gtccggaatt attagaactg acgccgcagg ctctgacggc gttaagcaat gccggttttg
    11821 ttaagcgcag ccttaaggaa ctggaaaatg gcaacgtccc ggaaatcagt catgagaacg
    11881 gcgctttaat cgccaccttc agtgacggtg tccgtaccca gctggcgaac ggccaggcac
    11941 tgaaagaggc tcagtgcacc tgcggggcca gcggcatgtg ccgtcatcgc gtgatgctgg
    12001 tgttaagtta tcaacgactt tgtgccaccg cccagcctac ggaaaaaaaa gaagaagagt
    12061 gggatccagc aatctggctg aaagaactgg ctaacctgcc cgatgccacc cgcaaacgcg
    12121 cgcaggcgct ggtcgctaaa ggcatcacca ttgagttgtt ctgtgcgcct ggcgaaattc
    12181 cctctgcccg attaccgatg agcgatgtgc gtttttattc ccgcagcagc attcgcttcg
    12241 cacgctgtga ttgcattgaa ggcacacttt gcgaacatgt cgtactggct gtgcaggcct
    12301 tcgtcgaggc caaaactcag caagcggaat ttactcattt aatctggcag atgcgcagtg
    12361 aacacgtgac atcatctgat gatccgtttg ccagcgaaga aggcaaaacg tgtcgtcaat
    12421 atgttcagca attaagccag gcattatggc tgggcgggat aagtcaaccg ccaatccatt
    12481 acgaggccgc tttcagtcgc gcgcagcaag cggcggaacg ctgcaactgg cgatgggtga
    12541 gtgaatcgct acggcaattg cgcgccagtg ttgatgcctt ccacgcccgt gccagccact
    12601 accatgccgg agaatgctta cgtcagcttg cggcattaaa cagtcgatta aattgcgtac
    12661 aagagatggc gcgacgcgac agtatcggtg aagttcctcc catgccgtgg cgcacggtcg
    12721 ttggcgctgg cattgccgga gaagcaaaac ttgatcatct gcggctggtg tctttaggta
    12781 tgcgttgctg gcaggatatt gagcagtatg gtttacgcat ctggtttacc gatcccgaca
    12841 caggaagtat tttgcatctt tcgcgtagtt ggcagagaag cgaacaggaa aactcaccgg
    12901 cagcgacgcg tcggctgttt agttttcagg ctggcgcact ggcaggtggg caaattgttt
    12961 cacaagctgc aaaacgcagt gccgatggcg agctgctgtt agcgacccgt aaccgcttga
    13021 gtagtgttgt tccactgtcg ccagacgcct ggcaaatgtt gagcgcgccg ttgcgccagc
    13081 cgggcattgt ggctttgcgg gaatatttac gccagcgtcc ccccgcctgc atacgaccac
    13141 tcaaccaggt cgataactta tttattctgc cggtagcgga gtgtatttcg ctcggttggg
    13201 atagcagccg ccagacactg gatgcgcagg taatcagcgg cgaaggagaa gataatgtgc
    13261 tgacgttatc ccttccggca tctgcctgtt ctccttttgc cgttgaacgc atggcggcgc
    13321 ttttgcaaca aacagacgac cccgtgagtc tggtttctgg ctttgtcagt tttgtagagg
    13381 ggcaattgac actggaacca cgggtgatga tgacaaaaac ccgcgcctgg gcgctggacg
    13441 cagaaactgc gcctgtggca ccgctacctt ctgccagcgt tctgcctgtg ccgtctaccg
    13501 ctcatcagtt gctgatgcgc tgccaggcgt tacttattca actgctccat aacggctggc
    13561 gctatcagga acagagtgct attggtgagg cagagttgct ggcgaatgac ctcaccgcgg
    13621 tgggttttta tcggctggca catgtgttgg gacaatttcg taatacagaa agcgaggcac
    13681 gggtagaagc aatgaataac ggtgttttgc tttgcgaaca attattcccc atgcttcagc
    13741 aacaaggatg aaatagtgct ttttattaag agttctactc ctgttccgga ctgctcacgc
    13801 cacagtatta ggcatatcct atatagcccc tggtgagagt caccagttcc ttgattaaat
    13861 aaaatggagt tttacatgaa ggctttcaat aagctgtttt cccttgttgt tgcatctgtt
    13921 ctggttttct ctcttgctgg ctgcggtgac aaagaagaat caaagaaatt cagcgccaat
    13981 ctgaacggca ctgaaattgc cattacctat gtctacaaag gtgacaaggt gcttaagcaa
    14041 tcttctgaaa ccaaaattca atttgcctcc attggtgcaa ccaccaaaga agatgccgcc
    14101 aggacacttg agccgttaag cgccaaatac aaaaacatcg cgggtgttga agaaaaatta
    14161 acctataccg atacctacgc gcaggaaaac gtgactattg atatggaaaa agtggatttt
    14221 aaagccctgc agggtatttc aggaatcaat gtttctgctg aagatgccaa aaaaggtatc
    14281 actatggcgc aaatggaact ggtgatgaaa gccgctggtt ttaaagaagt gaaataatct
    14341 gtcggcggcc atgtttcgca tggccgccat acccgtctta gcttttcttc acatgctggc
    14401 gcgctgccag tccacgcaga aaataacgta aaaattgatc gccgcattcg cggaagtttt
    14461 tatgatccgg tgcacgcatc atcgccgtaa tttccggcat cgaaacgcgg aactgctgtt
    14521 cggtgaggat tgccagaatg tcatcggttt taagcgaaaa cgcgatgcgt aattttttca
    14581 gcacgatgtt gttattaatg cgacgttccg gctccagtgc cggagcagac tcatccttgc
    14641 cgcgtttttc ataaatcagg ccattgagga atgaagacaa aacaatgtcc ggacaacgct
    14701 gaaaaccctc ttcgtcttct ttacgtagcc agacggcgat ctgttccgcg gtggcttcga
    14761 cattacccag cgccagaata cgcaccaggt cattattatt ggctttcaaa atgtagcgca
    14821 cgctgcgcag aatatcgtta cttagcatga ggccttcagg tgttgatgag gcaaaaagcc
    14881 attttagcag tcttttacag gccaatcgcc tcttttaagc ttttcagata acggcggctg
    14941 accggcacgg ttaagccatt acgcaaaatc aactcggcct ggccgttatc ttccagacgg
    15001 atctcctgta aatgcgcgag gttaaccaga tactgacgat ggcagcgcag taatggtgta
    15061 cgactttcca gggtacgtaa tgtcagttcg gtaaagccct ctttcccttc gtgactggta
    15121 acgtagacac cgctcatccg actgctgaca aatgccacat ctttcatttg cagcaaataa
    15181 atccgactat gccccgtaca agggataaat ttcagcgcct gttgattttc cggtaacagc
    15241 gaaacatcct gcttgctgcg ctcctgacgc aatcgcgcca gcgttttctc cagtcgcgct
    15301 tcatcaattg gcttcagcag ataatcaaag gcatgttctt caaaggcttt aatggcgtat
    15361 tcgtcaaacg cggtgagaaa aacaatatac gggcgatgtt ccgggtcaag catccccacc
    15421 atttccagac cactgatgcg cggcatctgg atatcgagaa acagcacatc cgggcgcagt
    15481 ttatgcaccg cgccgatccc ttccacggcg tttgaacact ctccaacgat ttcaatatcg
    15541 ctctgctcct gcaaaaatac gcgcaggttc tcccgtgcaa gcggttcatc atcgacaatt
    15601 aagactttaa tcatgcctcg tccctccatg gtagtcgtaa cgttattcgg gtgtaactat
    15661 caggctcaca ggcgacgctt atcccatagt catcgccaaa ccgttcacgt aaacgcttat
    15721 ccaccagatt catccccagc ccactggcat tggttaccgg ttgatacaaa ccggcattgt
    15781 cttcgatctc cagcatcaaa tgttgcccct cacgtcgggc gctgattgcc actcgccctg
    15841 tatccagcag ttgtgatgtc ccatgtttaa tggcgttttc cactatcggt tgcagggtaa
    15901 acgcgggcaa ttgctgctgg gataattctt gcggaatagc aatgttgacc tgcaaccgcg
    15961 actggaagcg cgccttttca atttgcagat aagcgttcac atgttcaatt tcgtcggcga
    16021 gagtaacaaa ctccgaaggc cgctttaagt ttttgcggaa aaaagtggaa agatactgca
    16081 ccagctggct ggcctgttcg ctgtcgcggc ggatcaccgc tttaatggtg ttaagcgcat
    16141 taaacaaaaa atggggattc acctgggcgt gaagcagttt gatctctgac tgggtgagca
    16201 tcgctttttg ccgctcatat tgcccggcga ggatctgcgc cgaaagcagt tgcgcaatcc
    16261 cctcgcccag cgtgcggttg attgaactga ataaacggtt tttggcttca tacaatttga
    16321 tggtacccat cactcgctga ttttcaccac gcaacggaat gaccagcgtc gaccccagtt
    16381 tgcattgcgg atgcaaagag caacggtaag gcacttcgtt gccatcagcg tagaccactt
    16441 caccggtttc aatcgctttt aaggtataag tcgaagaaat cggtttgccg ggtaaatggt
    16501 ggtcgtcacc aattccggta aaggccagca atttctctcg atcggtaatc gcgactgcac
    16561 caatatccag ctcctgatac agcacctgtg ccactttcat gctgttcact tcgttaaacc
    16621 cctggcgcaa aatgccttcc gtcgaggccg ccactttcag cgcagtggca gaaaaagccg
    16681 aagtgtattt ttcaaacatc gcgcgtttat cgagcaatat acgcataaac aacgccgcgc
    16741 cgacggtatt ggtgaccatc attggcgcag caatattact caccagacgc accgcatctt
    16801 cataaggtcg ggcgatcgcc aggatgatca acatttgcac catttcagcg acgaacgtga
    16861 cggcaccggc ggtaatgggg ttaaagactt tatcagtgcg cccgcgacgg atcaggatgc
    16921 tgtgaaccag gccgccgagc aatccttcaa cgatggtcga gatcatgcaa cttagcgcgg
    16981 tcatgccccc catcgaatat cgatgtaacc cgccggtcag accaaccagc ccaccgacga
    17041 ccggaccgcc gagtaagccg cccattaccg cgcctatcgc acgggtattg gcaatagaat
    17101 cgtcaatgtg caacccaaac caggtgccca tgatgcagaa gatggaaaag acgatgtagc
    17161 agagaaattt atgcggcaga cgaaccgtga cctgcattaa cggtatgaat aatggcgttt
    17221 tactcattaa ccacgcaatg actaaaaaaa cgcacatctg ctgaagcagc agcaacacca
    17281 gattaaaatc gtacataccc gcaaaccaca cttcccttta aaatgcgtaa catacattgc
    17341 ttgcgtttaa ctttctttga actcttgcag aaaaatgaga attcgtgagt acgatcactc
    17401 aaaatcgcct ggcaaaaata aaatcaccct atagatgcac aaaaaacggg caaaactacc
    17461 tggttcgcaa aactgcgtct aaagttaaac cgggacctcg cgagcaaggg tgagacgatg
    17521 gcgctttaca caattggtga agtggcgttg ctttgtgata ttaaccctgt cacgttacgc
    17581 gcgtggcaga ggcgttacgg attgctgaaa ccgcaacgga cagacggcgg ccatcggctg
    17641 ttcaacgatg ccgatattga ccggatccgc gagatcaaac gctggatcga caacggcgtg
    17701 caggtcagca aagtaaaaat gctgctcagt aatgaaaatg ttgatgtgca gaacggctgg
    17761 cgcgatcagc aagaaacatt actgacttac ctgcaaagcg gcaatctgca tagcctgcga
    17821 acgtggatca aagagcgcgg tcaggattac cccgcccaga cactcaccac acatctgttt
    17881 attcctctgc gccgacggct tcagtgccaa caaccgactc tccagacgct gctggcgatc
    17941 ctcgacggcg tactgatcaa ctacatctct atttgcctgg cttcggcgcg caaaaaacag
    18001 ggtaaagatg cactggtggt tggctggaat attcaggata ccactcgtct gtggctggag
    18061 ggctggattg ccagtcaaca aggatggcgc attgatgtcc tcgcccactc gctcaatcaa
    18121 ctacgccctg aactgttcga aggccgtaca ttgctggtgt ggtgcggtga taatcgaacc
    18181 tccgcccaac agcagcaact caccagttgg caagaacaag gccatgatat tttcccactc
    18241 ggcatttaat gattcgttaa caaatgcgct ttactgtaca atcctttcgt taacataagg
    18301 agtgcattat gcgcatagct aaaattgggg tcatcgccct gttcctgttt atggcgttag
    18361 gcggaattgg tggcgtcatg ctcgcaggtt atacctttat tttgcgtgct ggctgaacgc
    18421 ctgcaccagc ctttcaaaca ggcggtctgc gatgatcgcc gccagtgcca ccagtaacgc
    18481 tccctggatc acatacgcgg tattaaatcc gctaagtccg atgatgatgg gcgtacccag
    18541 cgtgctggcc cctaccgttg aggcgatcgt cgccgtacca atgttgataa tcaccgaagt
    18601 tcgcacgcca gccagaatca ccggagccgc cagcggtagc tcgaccttac gcagtcgctg
    18661 accacgactc attcccatac ctttcgcaac ttctgtcacg ctggcatcaa tcgctcccag
    18721 cccggcaagt gtcgcctgca ggacgggcag cacgccgtaa aggatcaagg cgataatcgc
    18781 tggtttcaga ccaaagccga tcaccggaac ggcaatcgcc agcaccgcga cgggcggaaa
    18841 agtctgccca acggcggcaa tagtttccac cagtgggcga aattccgcac cccacgggcg
    18901 agtgacagca attccggcac cagtaccaat gatcaccgca aacaaactcg aaattcccac
    18961 cagccagaaa tgagccagtg ccagagctgc aaaactttct tgctgataaa cgggtcgtgg
    19021 cagttgtggg aacaaggcag caaacagcgg ctggctataa ggtagccaga aaatcagtgc
    19081 cacaaacaaa gcaatgagcc agaacagcgg atcgcgcaac atcttcatac gcttacgcct
    19141 cctccagcag atcctgaaaa tgcagcgtgc cgcaaggctg gccctgcgtg ttcaccaccg
    19201 gcagcacctc gcatccccgc gcgacaaaca gagaaagcgc atcgcgtagc gtcatccttt
    19261 cttccagtgc ctcaccttca gcccgttctt cacggcgcac gtaatctgcc acgctacgta
    19321 acgaaagcag gcgtacaccc agctcactac gaccaaaaaa ctggcggaca aaatcattcg
    19381 ccggatgagt cagcatcgcc agaggattgc cctgctgcac gacttcaccg tgatccatca
    19441 ataccagatg ttctgccagc cgtagcgcct catcaatatc atgagtgacc agcacaatgg
    19501 tacgcccctg caaacggtga atgcgcgtca tctcttgttg caacgcgccg cgcgttaccg
    19561 ggtccagcgc gccaaaaggt tcatccatca gtaagacttg cggatcggca gccagtgcgc
    19621 gcgccactcc cacacgttgc tgctgaccac cggaaagctg atgcggataa cgctcacgca
    19681 aatttggctc cagccccagt agcgccatta attcgtcgat acgatcgtcg atccgcgccc
    19741 gtgaccattt ttgcaattgc ggcacggtgg cgatgttttg tgccacgctc cagtggggaa
    19801 acaggccaat agattgaatg gcatagccca tccggcggcg caactccagt actggcagcg
    19861 agcgaatttc ttctccggca aagcggatca ccccgctgtc atgctccacc aggcggttaa
    19921 tcattttcag agtggtggat ttaccggagc ctgatgtacc aatcagcacc gaaaaactcc
    19981 cttcctgaaa attgagattg agatcgttaa cggctttttg tgcgccgaac agtttgctga
    20041 catggctaaa ttcaatcatt acgtttcacc ttcagcagtg cgataagcaa atcgaacagc
    20101 gcgtcggtaa gcaccgccag aacaattacc gggatcaccc ccagcaacac taaatcaatg
    20161 gcactgctta gcagcccctg gaaaaccagc gcaccaaaac cgcctgcgcc gattaacgcc
    20221 gcaatcaccg ccatgccaac ggtttgcacc atcaccaccc gcaggctgcg cagaaatacc
    20281 ggtaacgcca gcggtaactg aacatgcagg aaacgctgca ccccgctcat ccccatcgct
    20341 ctggcgctct ccagcacatc gcgcgggatc tggttcaagc cgactactac gccgcgcacc
    20401 agcggcagca aggcatagag caccagcgca ataagtgcgg gtgtcattcc ggttcctgct
    20461 atgccgagcg ttcccagcca cggaaaggcc gtaaccagcg cggcaagcgg cgcaatcagc
    20521 aggccaaaga gcgctaccga aggcacggtc tgaatgacat tcagcagaga aaaaatcgcc
    20581 ccctgccgcg cggtggaaaa gtagcaccag atgcccaacg gcacaccaat cactaacgca
    20641 ggcagcaccg caccaaacag caacgtcaga tgttgtgcca gagcgtcgtc aaacacatcc
    20701 tgacggttgg cgtattcttt cattaacgag agatcgttaa gcgtgccgga gtacagcaac
    20761 cacagcggaa taatggcaat ctgcatatgc aacaaccagc gccacagcgg atgcgtggag
    20821 attcggcgga tggcatcgct acaggccagc agtgccagcg ccgcagccag ccagaaacca
    20881 ctgccgaggc tggtacgtgc cagcgcactg ccattttgcg ccagttgtgt cgccgccttt
    20941 ccagctcccc acaccagcaa tacgaagacg aattgcgcca gaatgagtgc aaaaatgctg
    21001 ccttttttag cgggaataaa acaggctgtc agccaggcgc aaccaacgcc caccagcatc
    21061 cagagagttt gcggccacag ctgccagaga tgacgcccct cacccgaaac taaacgatta
    21121 ggcgcgtaac tgataaacgg cagcgccgct gcgattgccg tcagcaacag cagcagcgcc
    21181 agaacaggat taatacgtag ataagtcacg ggaaattact tcgtccaccc tttttgtttc
    21241 aggtagtcgg cagccacttt tttggcatcc agtccttcca cagcaatgct ggcattcagt
    21301 tgctgcaatg ttttttcatc gaggctggcg aagactggct gtagccactg tgccatttgt
    21361 ggatactctt tcagcaccga ctcacgcacc actggtgcag gcgcgtagat aggttgcacg
    21421 ccttgcggat cgcttaaggt ttgcagcccc agcgccgcga ccgggccgtc agtgccgtaa
    21481 gccattgcgg cattaacgcc agaggtttgc tgggcagcgg ctttgatcgt taccgccgtg
    21541 tcgccaccag ccagtgacag caactgatcc tgaccgagct taaagccata ggctttttca
    21601 aacgcgggta aggcatcggc gcgttcaata aactctgccg aggctgccag tttgaaggtg
    21661 ccgccctctt gcagataacg actcaggtcg gcaagcgaag tgagcttgtt tttctctgcc
    21721 acatcctgac gcacggcgat ggtccaggtg ttatttgcag gtgcgggcgt cagccagatt
    21781 aacttgtttt gctctgcatc gagttttttg actttctcgt aaccttgctg cacgtttttc
    21841 cacgctgcat cgttttcatc tttaaagaag aacgccccat tgccggtata ttccggatag
    21901 atatccagct cgccagaagt gatcgcgccg cgcaccacag gagtcgttcc aagttgcact
    21961 ttatttaccg taggaacgcc gtgactttcc agcacctgca aaatgatatt gccgagcagc
    22021 gcgccttccg tatcgatttt tgaaccaacc ttaacggggg aagctgcctg tagcggcagg
    22081 ctcacggctg ccaacaaaac cagtgaacct gcccagacct ttgagagtgg catgatgctt
    22141 tcctcattct tttactgttg ttttcagcga attaagagaa aagcatagtt gataatgaca
    22201 gggttagcct gtctgggtgg attcagttgc agaatcagat aaatacttaa aaggcatatt
    22261 ttgcccggcg tttcttgccg gatgcggcgt aaacgcctta tccggcctac aaacatcgaa
    22321 aattacaaca actcaaactc ggctttctta acgcgtgcgg aatcagtgcc gataaagaca
    22381 ttgaacttgc caggctcggc gtcatatttc atctgttgat tccagaactt cagcgcctca
    22441 atatcaatcg ggaagctgac ggtctgagtt tcgcccggtt tcagagtgat tttctcaaag
    22501 cctttcagct gcttcaccgg gcgactcatg gaagccgtca catcctgcaa gtacatctgt
    22561 actaccgtgg ccccttcgcg tttaccggtg ttcgtcacct gcacgctggc cgtcactttg
    22621 ccgtcacgct tcatggtcgg cgcagaaagt ttcacatcag agacggtgaa agtggtgtag
    22681 ctcagcccat agccgaacgg ataaagcgcc ccgttagctt catcaaaata acgcgaagtg
    22741 tatttgttcg gcttgtcggc attatacgga cgcccggtat tcagatggct gtagtacacc
    22801 gggatctgcc cgacagaacg cgggaaggac atcggcagct tgccggacgg gttataatcg
    22861 ccaaacaata catcggcaat tgcattaccg ccttcagtcc ccgcaaacca ggtttccaga
    22921 atcgcatcag cctgctgatc ttctttcacc agcgccagcg gacgcccatt catcagcacc
    22981 agcaccagcg gtttaccggt ggctttcagc gccgcaatca agtcacgttg gctttgcgga
    23041 atagtgatat cggtacgact ggaagcttcg tgcgccatcc cctgagcttc accgaccaca
    23101 gccaccacca catcagattg tttcgcggtt tgcaccgctt catcaatcat ctcttgcggc
    23161 gaacgcggat cgactttgac cgcttcttca tactgattca ggaaatcgat aatgcctttg
    23221 tcactggtaa cgttcgcccc tttggcatac agcactttac cgttttcacc gacggcgttt
    23281 ttaatcccgg ttagcacagt aacagattga tcggcgacac ctgctgccga ccagcttccc
    23341 atcacgtcac gcttgctgtc tgccagcggg ccaaccaccg caatggttgc agattttttc
    23401 agcggcagcg tttcgagacg gtttttcagc aacaccaggc tttcgcgcgc cacttcacgc
    23461 gcttctttgc ggtgcaggcg gctttcggca ttggtatcca ccgggtcaga ctctttcggc
    23521 cccaaatggc tgtatggatc gttaaacaat cccatatcat atttaacgtt cagtacatgg
    23581 cgggcagcat cgtccagctc ttccatcgtc actttgccgg atttgatcaa cccaggcaga
    23641 tacttcgagt aatactcgtc gctcatgctc atgttgattc cggacttcag cgccacgcgt
    23701 accgcatcct ctgggtctgc cgccgtgcca tgtttaatca gttctttgat tgcgccgtga
    23761 tcggaaacgg tgatgccttt aaagccccac tggtcgcgca gaacatcttt cagcagccag
    23821 gagtcggagg tggctggcgt gccgttcagc gagttcagcg ccaccatcac cgcaccgctg
    23881 cctgcatcca gccccgcttt gtacggcggc atatagtcgt taaacaggcg ctgcggactc
    23941 atatcgacgg tgttgtactc tttaccgcct tctaccgcgc cgtatgcggc aaagtgtttg
    24001 acgctggtca tcaccgagta gcgatctgcc gggcttttac cctgcatcgc ttccaccatg
    24061 gttttaccca ttattgaggt gagatacgta tcttcgccaa aaccttcgga agcacgtccc
    24121 cagcgcggat cgcgcgagac atcgaccatc ggtgcccagg tcatattcag gccatcatct
    24181 gccgcttcat aagcagagac acgcccgact gttttcaccg catcgaggtt aaaagacgag
    24241 gccagaccga gactaatcgg gaacaccgtg cgctgaccgt gcagcacgtc gtaagcaaag
    24301 aaaagaggaa ttttcaggcg gcttaattcc atcacctgat cctgcatggc gcggatatcc
    24361 tgacgggtta cggtgttgaa aatcgcccca acctgaccgt ctttgatcat ctcgcggatc
    24421 gcctctttcg ggttatccgg gccgacgctg attaagcgca gctgaccaat tttctcatca
    24481 actgtcattt tcttaagcag ttcggtgacg aacgcatccc gcgcttcggg cgttaatgga
    24541 tggttgccga ataaatcatc cgccagtgct ggctgcaggg ccagactcac cgcgattcct
    24601 actgaacata gccatttcat atggattttt cttcctttgt tgcccgacgt ggcagcgaaa
    24661 atggtgcaaa aaccgtagtt tgccataagc atgatggaga gagaaaaaga atgctcagtt
    24721 tattgtctga attttcaaaa tattcactcg ctgaattgtc atacaaggcg ctattctagt
    24781 ttgtgatatt ttttcgccac cacaaggagt ggaaaatgtc ttccatgaca acaactgata
    24841 ataaagcctt tttgaatgaa ctttcccgtc tggtcggtca ttcacacctg ctcaccgatc
    24901 ccgcaaaaac ggcccgctat cgcaagggct tccgttctgg tcagggcgac gcgctggctg
    24961 tcgttttccc tggctcacta ctggaattgt ggcgggtgct gaaagcctgc gtcaccgctg
    25021 acaaaattat tctgatgcag gcggccaata caggcctgac cgaaggatcg acgccaaacg
    25081 gtaacgatta tgatcgcgat atcgtgatca tcagcaccct gcgtctcgac aagctgcacg
    25141 tactcggtaa gggcgaacag gtgctggcct atccgggcac cacgctctat tcactggaaa
    25201 aagccctcaa accgctggga cgcgaaccgc actcagtgat tggatcatcg tgtataggcg
    25261 catcggtcat cggcggtatt tgtaacaact ccggcggctc gctggtgcaa cgtggcccgg
    25321 cgtataccga aatgtcgtta ttcgcgcgta taaatgaaga tggcaaactg acgctggtga
    25381 accatctggg gattgatctg ggcgaaacgc cggagcagat ccttagcaag ctggatgacg
    25441 atcgcatcaa agatgacgat gtgcgccacg atggtcgtca cgcccacgat tatgactatg
    25501 tccaccgcgt tcgtgatatt gaagccgaca cgcccgcacg ttataacgct gatccggatc
    25561 ggttatttga atcttctggt tgcgcaggga agctggccgt ctttgcagta cgtcttgata
    25621 ccttcgaagc ggaaaaaaat cagcaggtgt tttatatcgg caccaaccag ccggaagtgc
    25681 tgaccgaaat ccgccgtcat attctggcta atttcgaaaa tctgccggtt gccggggaat
    25741 atatgcaccg ggatatctac gatattgcgg aaaaatacgg caaagacacc ttcctgatga
    25801 ttgataagtt aggcaccgac aagatgccgt tcttctttaa tctcaaggga cgcaccgatg
    25861 cgatgctgga gaaagtgaaa ttcttccgtc cgcattttac cgaccgtgca atgcaaaaat
    25921 tcggtcacct gttccccagc catttaccgc cgcgcatgaa aaactggcgc gataaatacg
    25981 agcatcatct gctgttaaaa atggcgggcg atggcgtcgg tgaagccaaa tcgtggctgg
    26041 tggattattt caaacaggcc gagggcgatt tctttgtctg tacgccggag gaaggcagca
    26101 aagcgttttt acaccgtttc gccgctgcgg gcgcagcaat tcgttatcag gctgtgcatt
    26161 ccgatgaagt cgaagacatt ctggcgctgg atatcgctct gcggcgtaac gacaccgaat
    26221 ggtatgagca tttaccgccg gagatcgaca gccagctggt gcacaagctc tattacggcc
    26281 attttatgtg ctatgtcttc catcaggatt acatcgtgaa aaaaggcgtg gatgtgcatg
    26341 cgttgaaaga acagatgctg gaactgcttc agcagcgtgg cgcgcaatac cctgccgaac
    26401 ataacgtcgg tcatttgtat aaagcaccgg agacgttgca gaagttttat cgcgagaacg
    26461 atccgaccaa cagtatgaat ccggggatcg gtaaaaccag taagcggaaa aactggcagg
    26521 aagtggagta ataattacgg atggcagagt atcgccatcc gtcattcatt taatcgttct
    26581 gtgccgtctg ccccgccgcc gccatttggg cggctttttg ttttttatag ctcaacgctg
    26641 ctgccggaac aggcatcact ttaccggttt caatccaggt acgcaggcgg ctggcatcgg
    26701 caaaatgggt atatttgcca aacgcgtcca tcactaccag cgccaccggt ttattattga
    26761 taaccgtgcg catcaccaga caatggcccg ccgcattggt aaaaccggtt ttggttaact
    26821 gaatattcca gttatcacga tacaccagat ggttagtatt gcggaacggc agcgtatacg
    26881 tcgggttaga gaaggttgcc atatcttccc gggtagtact taactgcccg atcaacggat
    26941 attgtttgct ggcaatgagt agtttggtta agtcacgggc ggttgaaacg ttatgcaccg
    27001 acaatccggt tggttcaaca aagcgcgtgt tgttcattcc gagcgatttc gctttcgcat
    27061 tcatcgcctt aataaaggct ttgtaaccac cgggataatg gtgcgcaagg cttgccgccg
    27121 cgcggttttc tgaagacatc agcgccagca acagcatatc tttacggctg atttcgctgt
    27181 tcagtcgtac gcgcgaatag acccctttca tctccggcgt ctggctgata tccactttta
    27241 gtttttcatc cagcggcagt cgtgcatcca gcacaaccat cgcggtcatt aatttgctga
    27301 tagacgcaat cggacgcacc agatccgggt ggttcgaata gatcactttg ttggtattca
    27361 gatcaacaat catcgcgcta ccggaggcaa tttccggttg tgacgcggtg gtagcggctg
    27421 ccgttttcgc aacggcctgc ggtgcaaaag gcacagccag catcagggcc aggctaaata
    27481 aagaaactcg aaatttcggc atgatgagca ttcagatagt ggttcacgcg cacgggttgc
    27541 gcaccgccgg agtaaggatt tactgaggct agcgacgcca tcataacgag caaaaagtgc
    27601 gatcgtcaaa ggagaatcgt gaggaaatgc tgcattgctg acatttacgc cagcaatgca
    27661 gcgcaaaaga actttctaga acaaacgata accgtagccc catagtataa cggtaagggc
    27721 gagcagcact tccagcacca gcacgcctat cgccagtgtc gaactggaga agctaagtcc
    27781 ttcctctttg ttgatattca ggaagctcgg aataccgaga tacagcaggt agccggtgta
    27841 aaacagcgcc accgtgccga ccagcgcaca caaccagacc agcgggtaaa gcgccaccag
    27901 accgcttaaa aacagcggag ttgcaacgta gcccgcgaag accatgcagt gcgcaagtga
    27961 cggacgctgc ggataattac gcgccatcca ccagatgacc cgccccatca ccgcaacccc
    28021 agccagcata acgccgtaaa acaagacagc cagcgccagt ccggtaaacc aggataactt
    28081 caggatagtg ccatcgccaa aattccagcc aatctgtgta gtgccaatga aggcgcaaat
    28141 caccggaatc gccgccatca gcaaaacgtg gtgggtgtag tgatgagaaa tcgtttcgtt
    28201 ttcgcgatta atcacctgca tttcacgatc gggatgggaa aacagtcccc agacatggct
    28261 cataccgccc ccttgttgtg agttcatgaa cctgacagtt caagtataag tcagcttgtg
    28321 attatttttt gttcactcat gtaatttgca ccgtctgatg tacgtccttt ttcagcgtga
    28381 atgattcaca gggtgtatgc ttacaggcaa gcaaagggag acagactgtc ctatggatct
    28441 caatacactc atctcacaat atggttatgc cgcgctggtg atcggtagcc tggcggaagg
    28501 tgaaaccgtg actttgctgg gaggcgttgc ggcacatcag gggctattaa agttcccgct
    28561 ggtggtactt tctgtggcgc ttggcggcat gattggcgac caggtgcttt atctgtgcgg
    28621 gcggcggttt ggcggcaagc tattacgccg tttctcgaaa catcaggata aaattgagcg
    28681 ggcgcagaaa ctgatccaac gccatccgta tctgtttgtc attggtacgc gttttatgta
    28741 tggctttcgg gtcattggcc cgacgctgat tggtgccagc cagctgccgc cgaaaatctt
    28801 tctgccactg aatatcctcg gcgcatttgc ctgggcgttg atttttacca ctatcggtta
    28861 cgctggtggt caggtgattg cgccgtggtt gcataatctc gaccagcatt tgaagcactg
    28921 ggtctggttg attctggtcg tggttctggt ggtaggcgtg cgctggtggc tgaaacgacg
    28981 cgggaagaaa aagccggata atcaggcgta aaaccattgc ctaggataag gcgttcgcgc
    29041 cgcatccgac atccggtgca ccatgcctga tgcgacgctt gtgcgtctta tcatgcctac
    29101 ccaaatatta cccattgaaa taaccacgca cctcactgcg ctattctggg ttgaactgcg
    29161 gattcgccag cataaagccg ccatccacta tcaacgactg cccagtggtg taatttgcgc
    29221 cctccgaaca aagccacacc accaggctgg caatctcatg cgttgcgcca aaacgccgca
    29281 agggaatcga aggctccgcg ccgggcttca cgtcgccatc atccatgccg ttcattggcg
    29341 tggcgatcgc cccaggtgca accgcattca ccaaaatctt atgcctgacc agctccagcg
    29401 ccatcgcttt ggttaacccg ccgagcgcat gtttagcggc tgtgtaggcg ctggcatccg
    29461 gcaacggcgt atgttcatgc accgacgtaa tgttgatgat gcgaccaccc tgcccttgtt
    29521 tcaccatctg gcgggcagca atttgcgagc ataaaaatgc accatcgaca tcaacggtaa
    29581 aaatcttgcg ccactcatcg aaagccatat caagaaacgg cgctttggtc attgcgcccg
    29641 cattattcac cagcacatca atacgcccca gccgttgaat gagtttctcc agcgccagtg
    29701 ccccttctgg tagattgccg agatccagct gcacgatctc cgcacgtacg ccgtggctaa
    29761 ctacctcacg cgcggtatct tttgcccctt cttcatctga gtgccaggta atgccaatat
    29821 caaacccctg ctgcgccagt aataacgcgc actctttgcc gatccccgaa tcggaggcgg
    29881 taataatcgc gacctgtgcc atcgagttct ccacttaacg ctgaataaac gttaagtata
    29941 gaaggcgcat atcatcagcg tttgtaaccc ccgcccaacg caccagtgag ttgaatggag
    30001 gcatccagcc actgcccttg caataacagg ccattggccc gctcacgcag cgcggggatt
    30061 ctggcttcgc tgacgcggga acccgcaatg atgcccgcgt taaagcgcgc ctgcgcaaga
    30121 cctactacac gcaaggcatc gcgctcaatt tgcgcctgat gctggttttt ctccgccagt
    30181 gtctgaacct gactggctgc ccgcgccacg tcattcaccg cttcaaccac cgctttgttg
    30241 tagctggcga tagacaagtt gctttcggct tttgcgatat cgaggttggc gttaagacga
    30301 ccactatcga aaatgggtag cgtcaggcct gccgtaacgc ccatttgctg cgcggaatga
    30361 cggaacagat cgcttaagtg caacgcatcc tgttgcagga aggccatcag gttgatgtca
    30421 ggataaaatg ccgcttttgc cgcatcaata gtgcttaacg atgactcaac gtaccagtgc
    30481 gccgcctgca aatctgcccg ccgggccagt aaggagtacc ccagttcatc aggaagctga
    30541 cttgccactt tcggcaacgc gaccggatta agcttcaatg cctttgtctg gtgatttgta
    30601 agtgcgctta accgtgcctc aataattttc attttccccg cgacatcgtt gagctgctgc
    30661 cgggttttgc tggcattaat atcggtttcc acaccttcaa ctgaagaagt aatcccgttc
    30721 tgatatagct ggcgatcggt ggcgataatg gtgttctgct ctttttcgat ttgctgtaag
    30781 acagtgttta acgccgcctg ggtttgccac tcccagtaca ggcgggctac gctgccagcc
    30841 agcaattggc gggtttgctc gcgttccgcc gctcgtgctt taaccgtacc caggcgagca
    30901 gttacctctg cccgattctt tccccagata tcgagatgcc agcccgccgt taagccaaaa
    30961 gtaccgttgg tgtaccacgg accggtcgta cctgcggcag gatcgttcag agcaaacggc
    31021 cccattaacc cttctgcaga cattttttgc cgctccatat ccgcagaaaa gtcgatctgc
    31081 ggaccatcct gagtagcaac tgccttcgcc tgggcttcag ccagttgaat gcgctgttca
    31141 gccacctgca tatccggtgc gttctgtagt gcattgttaa ttaaggaagt gagttgatta
    31201 tcgtgatact ccagccacca ttggctgtct ggccaaccat ttttcagcgc cgtgggtaat
    31261 gcggtgtcaa cttgtgcagc gggcgtttgc tggcttaacg cctggcgggt ttcatgcata
    31321 ggtgcacacc cggccagcat cagtaacagc ggaaaacagg cgatggcggg ataaaaggaa
    31381 tcacgattca tgggggaata atcaggtaag aaaaggtgcg cggagattac cgtgtgttgc
    31441 gatatatttt ttagtttcgc gtggcaatac atcagtagca ataaaacgac atatccagaa
    31501 aaatatacac taagtgaatg atatcttccg atttatctta atcgtttatg gatagcggca
    31561 aagggcttcg ttttttccta tacttattca gcactcacaa ataaaggaac gccaatgaaa
    31621 attatactct gggctgtatt gattattttc ctgattgggc tactggtggt gactggcgta
    31681 tttaagatga tattttaaaa atcagatatg gcatataagt tgtcaggtca ggaactagat
    31741 attttgtgta cttgatttgc aaacagctcc ggtgttggtg gcgtcaaaat cgctgaagcg
    31801 ttccccgaag gccggggcag cccacatgga tgtgggctga gggcgcgtct tacaaggacg
    31861 ttacctcgcg cccgacccgg tagccgaagg ggataagctg aaggtaccgc gcagcggcga
    31921 ttttgttcgc cagagcccgg gggtgcaggg ggaggaggcg attgtcctcc ccctgcgcgc
    31981 tccttgcgcc agtggcaata tgtggcttag ctcatgaaag gagcgcaaca agatgatgaa
    32041 gctgaataag cgattcattg tctcagataa gctgcgattc cactattatc gcagcttatc
    32101 gatatcaatg gcctgaatag cccttgcaat atcaggggaa ttattcaaca cccgaacatg
    32161 ctgaaataat tccgttgctt catcgtattc tttacgcaaa taactcaacc actgtttaat
    32221 ccgcgcaacg tgatataacc cggtatcgcc ctgcttttcc agacgggtat atttttgcag
    32281 caaagcaacc acctccggcc acggcattcg cggttcgtta tatttcacca cacggctcag
    32341 gttgggaata ttgagcgccc cgcgaccaat catcactgcg tcgcagccgc tgatcgccat
    32401 gcattgttgc gcactctgcc agtcccagat ttcaccgttg gcaatcaccg gaatattaag
    32461 ccgctggcga atctcgccaa tcgcctgcca gtcaatatgt tccgcgcggt aaccctgctc
    32521 ttttgtccgc ccatgtacta ccagctccgt agcaccagcc tgttgaaccg catcggcgat
    32581 ttcaaatttc ttctcaccgc tgtcccagcc cagacgcact tttacgctga caggcaaatg
    32641 cgccggtaca gcttcgcgca tcgcttttgc accctggtag atgagttcag gatctttcag
    32701 taacgttgcc ccaccaccgc taccgttaac cgttttcgac gggcagccgc agttaagatc
    32761 cacgccccag gaacctaact ccaccgcacg ggcggcgttc tctgccagcc actgtgggaa
    32821 ctgccctaac aactgcacgc gaaccagcgt accggatggt gtccggctgg cattttgtag
    32881 ctcagggcaa atgcgatgaa agacttttac tggcagcagt tgatccacca cgcggacaaa
    32941 ctcggtgatg cacagatcgt agtcgttaac ttcggtcagt aattcccgca ccagagagtc
    33001 aagtacaccc tccatcggag ccagtaacac acgcatatca tcacccgcaa aaaaatgagg
    33061 cgctatgtta gcgcctccgg tcaacggatt aaaggtctgc aaagagggat tgctgcaaac
    33121 tgcaatccct ctctatgctt gatgtatgcc tgagttcgct gcgcattgcg taataccggg
    33181 gagcgaaaaa ataagcgctg atttcttaat gtgatcggta gcacgtttta cgaattaatt
    33241 gtatgatgaa tccatctcat ctggggtgtt gattatgagt aagacactga acattatctg
    33301 gcaatattta cgtgcttttg tcctgattta tgcctgcctg tatgcaggca ttttcattgc
    33361 ttccctgcta ccggtaacca ttccgggcag catcatcggg atgctgatcc tgtttgtcct
    33421 gctggccttg caaattcttc cggcgaaatg ggtcaatccg gggtgctacg tactgattcg
    33481 ctatatggcg ctattgtttg tgccgattgg tgtaggcgtc atgcaatatt ttgatttgct
    33541 ccgcgcacag tttggtccgg tagtggtttc ctgtgcagtc agtacgctgg tggtttttct
    33601 ggtggtgagc tggagttcac aactggtgca tggtgaacgt aaagtcgtag gtcagaaagg
    33661 atcagaagaa tgatggcgaa tatctggtgg tcattaccgc tgacgttgat tgtctttttt
    33721 gccgcccgca aactggcggc acggtataag tttcccctgc ttaacccgtt gctggtagca
    33781 atggtggtga tcattccttt tttaatgctg accggcatct cttacgacag ctactttaaa
    33841 ggtagcgaag tgctaaacga tctgctgcaa ccggcggtcg tcgcactggc ctatccttta
    33901 tatgagcagc tacaccagat ccgcgcgcgc tggaaatcga tcatcaccat ctgttttatc
    33961 ggcagcgtgg ttgcgatggt gacggggact tctgtggcat tgttgatggg cgcttcaccg
    34021 gaaatcgccg cgtcaatcct gccgaaatca gtcaccacgc ctattgcaat ggcagttggc
    34081 ggcagtattg gcggtattcc ggcaatcagc gcagtttgcg tgattttcgt cggcatcctc
    34141 ggcgctgtgt ttggtcatac attgcttaat gcgatgcgta ttcgtaccaa agctgcgcgc
    34201 ggtctggcaa tggggacagc ctcgcacgcc ctcggtacgg cgcgctgcgc cgagctggat
    34261 tatcaggaag gtgcatttag ttcgctggcg ctggtgttat gcgggattat tacttcgctg
    34321 atcgcaccgt tccttttccc gattattctg gcagtaatgg gctaaaattt gcgatgcgtc
    34381 gcgcattttt gatgtaagtt tcacgcgttg cataattaat gagattcaga tcacatataa
    34441 agccatagcg ggttcgtaaa ctgttatccc attacatgat tatgaggcaa cgccatgcat
    34501 ccacgttttc aaaccgcttt tgcccaactt gcggataact tgcaatctgc actggaacct
    34561 attctggcag acaagtactt ccccgctttg ttgaccgggg agcaagtctc atcgctgaag
    34621 agcgcaacgg ggctggacga agacgcgctg gcattcgcac tacttccgct ggcggcggcc
    34681 tgtgcgcgta cgccattgtc gaattttaat gttggcgcaa ttgcgcgcgg tgtgagcgga
    34741 acctggtatt tcggtgccaa tatggaattt attggtgcga caatgcagca aaccgttcat
    34801 gccgaacaaa gcgcgatcag ccacgcctgg ctgagtggtg aaaaagcgct tgcagccatc
    34861 accgttaact acacgccttg tggtcactgc cgtcagttta tgaatgaact gaacagcggt
    34921 ctggatctgc gtattcatct tccgggacgc gaggcacacg cgctgcgtga ctatctaccg
    34981 gatgcctttg ggccgaaaga tctggagatt aaaacgctgc tgatggacga gcaggatcac
    35041 ggctatgcgc tgactggtga tgcgctttct caggcggcga ttgcggcggc aaaccgttcg
    35101 cacatgcctt acagtaagtc gccaagcggt gtcgcgctgg aatgtaaaga cggtcgtatt
    35161 ttcagcggca gctacgctga aaacgccgca ttcaacccga ctctgccgcc gttgcagggg
    35221 gcgttaattc tgttgaatct caagggttat gattacccgg atatccagcg cgcggttctg
    35281 gcagaaaaag ccgatgcgcc gttgattcag tgggatgcca cctccgcaac gctgaaagct
    35341 ctcggctgtc acaatatcga ccgcgtgctt ctcgcttaag cctggtgccg gatgcggcgt
    35401 gaacgccttg tccggcttgc cagccctttc ctggtgtcga aaatcccggc aaacagtttg
    35461 ccgtttcttg cgcaaaacca gcgggtaaag tagcctgatg gaaattttcc ttagatcgag
    35521 tctcctgcat gttaaagcgc gtgttcctca gcctgttagt cctgatcggc ttgctgctgt
    35581 tgactgtgct cggcctcgat cgctggatga gctggaaaac cgcgccttat atctacgacg
    35641 aattgcagga tctcccctac cgccaggtcg gtgtggtgct cggcacagca aaatattatc
    35701 ggactggcgt aattaatcag tattatcgct accgcattca aggagcgatt aatgcctata
    35761 acagcggtaa ggtaaattat ctattactga gcggcgataa cgcattgcaa agttataatg
    35821 agccgatgac catgcgcaaa gatttaatcg cagccggtgt cgacccatca gatattgttc
    35881 tcgattacgc aggctttcgt acgctggatt ccatcgtacg tacacgcaaa gttttcgata
    35941 ctaatgattt cattattatc acccaacgtt tccactgtga gcgggcatta tttattgcgc
    36001 tgcatatggg gattcaggct cagtgttatg ccgtaccgtc accgaaagat atgctgtcag
    36061 tacgtattcg cgaatttgcc gcccgtttcg gtgcgctggc tgacctttat atttttaaac
    36121 gtgaaccgcg ttttttaggg ccgctggtcc ctattccggc aatgcatcaa gtgccggaag
    36181 atgcgcaggg gtatcccgct gtcacacccg aacagttact tgaattacaa aagaaacaag
    36241 gaaagtagtt atggatgtac agcagttttt tgtcgttgcc gtttttttcc ttatcccgat
    36301 attttgtttc cgcgaagcat ggaaaggctg gcgcgcaggc gcgattgata aacgggttaa
    36361 aaatgcaccg gaaccggtgt atgtctggcg agcgaaaaat cccggactct tcttcgctta
    36421 tatggtggca tatatcggct tcggaatttt atctatcggc atgattgttt atcttatttt
    36481 ctatcgttaa tattttctct tttctgttaa ttattgagaa taattattac ttcactcaat
    36541 aagctgcgga tataacattc tgaaccgcag ctatttgtga atcctttcac agtttaaatt
    36601 tccccacgcg catagcctta atatcagcac gcaatattta tttagcgttc gccttaatta
    36661 ctcatagcat taaggaagat cacatgccgc aacaaaatta tctggatgaa ctcactccgg
    36721 cttttacgcc tttactggcg attaaagaag cctctcgctg tttattatgt catgacgctc
    36781 cctgtagtca ggcttgcccg gcacagaccg atccggggaa atttattcgc tcaatctact
    36841 ttcgtaattt taaaggcgct gccgagacaa ttcgcgaaaa taatgccctc ggtgccgttt
    36901 gtgccagagt gtgcccgacg gagaaattat gccaaagcgg ttgtacacgt gccggtgttg
    36961 atgctcccat tgatatcggt cgcttacagc gttttgttac tgattttgaa caacaaactg
    37021 ggatggaaat ttatcagccc ggtactaaaa cgctcggcaa agtcgccatt attggcgcag
    37081 gtcctgccgg attgcaggcc agtgtgacgc tgacaaacca gggttatgac gtcacgatct
    37141 atgagaaaga agcacaaccc ggtggctggt tgcgtaacgg cattccgcaa ttccggttac
    37201 cgcaatcggt gctggatgca gaaatcgccc gtatagaaaa aatgggcgtg accattaagt
    37261 gcaataacga aatcggtaaa acactcaccc tggagcagct gaaagcggaa aaccgcgcgg
    37321 tactggtcac cgtagggtta tcgagcggtt ccgggttatc gctgtttgag catagcgacg
    37381 ttgagattgc cgttgacttc ctgcaacgtg cacgacaggc gcaaggcgat atcagcattc
    37441 aacaaagcgc attaattatc ggcggcggtg atgtcgcgat ggacgtagcc agcacgctga
    37501 aagttctcgg ctgtcaggcg gtaacctgcg tagcgcgtga agagttagat gagtttccgg
    37561 caagcgaaaa agagtttacc agcgccagag agctgggcgt ttcgatcatc gatggattta
    37621 caccagtagc cgtggaaggc aataaagtca cctttaagca tgttcgttta ccgggtgaac
    37681 taacgatagc ggcggacaaa attattctcg ctgtaggtca acatgccgaa cttgctgctt
    37741 tttccgcact ggaaccgcaa cgtaacacca tcgaaacgca acattaccag acccgcgacc
    37801 cgcaagtctt tgctgctggc gatattgttg agggtgacaa aaccgtggtc tatgcagtga
    37861 aaaccgggaa agaagccgcc ggggcgattc atcactattt agagggagct tgctcatgtt
    37921 aacgaaagat ctttcgatta ctttttgcgg cgtgaagttt cccaacccgt tctgcctttc
    37981 ttcttcgccg gtaggcaact gctatgagat gtgcgccaaa gcctacgaca caggttgggg
    38041 cggcgtggtg tttaaaacga tcggtttttt tatcgccaac gaagtctcgc cgcgttttga
    38101 tcatctggtg aaagaagata ccggttttat cggcttcaaa aatatggagc agattgctga
    38161 acatccgttg gaagagaatc tggccgccct gcgtcggctg aaagaagatt acccggacaa
    38221 agtattgatc gcttcaatca tgggcgaaaa tgagcagcaa tgggaagagc tggcgcgtct
    38281 ggtgcaagaa gctggcgcgg atatgatcga gtgtaacttc tcctgtccgc aaatgacttc
    38341 tcatgcgatg ggtagcgatg tcgggcaaag cccggagctg gtagaaaaat attgtcgggc
    38401 agtaaaacgt ggttccacgc tgccaatgct ggcgaagatg acgccgaata ttggtgatat
    38461 gtgcgaagtg gcgctggcgg cgaagcgcgg cggcgcagat ggcattgcgg cgattaacac
    38521 cgttaaatcc atcaccaata tcgatcttaa tcagaaaatt ggtatgccga tcgttaacgg
    38581 taaatcgagt atttccggat attccggtaa agcggtaaaa ccgatcgccc tacgctttat
    38641 tcagcaaatg cgcacccatc cagaactgcg cgatttcccg atcagcggta tcggcggcat
    38701 tgaaacctgg gaagatgcgg cggagttttt attgctcggt tcagcgacgt tgcaggtgac
    38761 caccggcatt atgcagtacg ggtatcggat agtggaagat atggcaagcg ggttgtcgca
    38821 ttatctcgcc gatcaagggt ttgattcgtt gcaggagatg gtaggtctgg cgaatcacaa
    38881 tattgtcccg gcggaagatt tagaccgcag ttatattgtc tatccccata tcaatcttga
    38941 taaatgtgtt ggctgtggac gctgttatat ttcctgttac gacggcggtc accaggcgat
    39001 ggaatggagc gagaaaaccc gcacaccgca ttgtaatacc gagaaatgcg tgggttgtct
    39061 gctttgtggt cacgtctgcc cggtaggttg tattgatctt ggggaagtga agtttaagaa
    39121 aggcgagaaa gaacacccgg taacgttgta aaaccagcga cgcatccggc atttagttcc
    39181 tgtcgccaga tgcggcgtga atgccttacc cggcatacaa aacaatataa atcagtatgt
    39241 tgtgctcatt gtaggccgga taaaacgcgc cagcgttgca tccggcattt ggctcctgtc
    39301 gccggatgcg gcgtaaacgc cttatccggc ctacaaaacc acacagatca tgatgttatg
    39361 tgcgtttatg aacgaatgcg gaccacattc acatcatttc ttacgcgcgt atttcagtga
    39421 atccagcgcc acggcaaaga taataattgc ccctttgatg atgtactgcc agtacgggtt
    39481 tacgccgatg tacgtcaggc catagttgat gacggtaaaa ataatcaccc cggtcaccac
    39541 gccaatcacc gtccctacac cgccgctgaa cgatacgccg cctaccacgc acgctgcgat
    39601 agcatccagc tcatacatga agccgaggtt gttggtggca gagccgatac gtccggcttc
    39661 taacatcccg ccgaaggcat agaacacacc agacaacgcg tagatcatca gcaggttcag
    39721 gccgacgttg acaccagata ctttcgccgc ttccgggtta ccgccaatgg caaaaatgtt
    39781 cttgccgaag cgggttttgt tccataacac ccagacaaac accaccgcaa tcaacgcata
    39841 gaaggtgatg taagagagac ggaaactccc cagcgcaata aagccttggg caaaagtgga
    39901 gaaaccactg tcaaaaccgg aaattggcga cgccccgaca aagtcgtaat agagcgagtt
    39961 aatgccgtag acgataatca tcgtaccgag cgtggtaatg aacggcgtca cgttgagata
    40021 ggcgataatc aagccgttga tcaaaccgat caccgcacca atggcacaga caatcagaat
    40081 aaccagcgca atcggcatcg tcgccatttc cgggaacact ttgttggcgt tatccatgga
    40141 ctgcaataac gtcgctgcta ctactgccgc cagccccacc tggcgacctg cggaaaggtc
    40201 agtcccctgg gtgacaatta accctgccac accaagcgcg ataataatac gcaccgatga
    40261 ctgggtgaga atattactta agttcaacag acttaaaaat gttgggtcct ggaaaataat
    40321 aatcgccagc aaaactaaaa gaacgacgta aataccgccc tctttcaggt aagtaagaaa
    40381 acttttctta tttaacgcac tcatgggaag cccctaatct taaaggtgca aagacgcaag
    40441 acgcagaatt tcgctttgcg ttgttgtttt tgtatcgaca attccggaaa cgagaccatt
    40501 gctcatgacc agaatacggt ctgttatccc taacaactct ggcatttcgg aggagataat
    40561 aataatcccc ttgcctttct tcgccagttc ggcaattaac tgataaatct caaacttagc
    40621 cccaacatca ataccgcgcg tcggttcatc gagcattaat atttctggtt gcgttaacag
    40681 ccagcgacca ataatcactt tttgctgatt accaccggag agcgaaccaa tttgcgtccg
    40741 atgccccggt gtttttaccc gcatcgaatc aatcacccac tgggtatcgc ttttcatccg
    40801 cgagttatcc agtaaaccaa ctttattttt atagttgcgg atattggaaa ttaacgagtt
    40861 aaagccaata tccagatagg cataaattcc cgttgagcgg cgctcttcag ttaccagtgc
    40921 aaatccgtgg tttatggctt cgttggcatt atggttattg atctttttgc cgtgcaacgt
    40981 aatggtgcca gccgatttct cgcgaatacc aaataacgtc tcaacaatat cggtacgttt
    41041 cgctcccacc agaccggcaa taccgaggat ctccccttta tgcagatcaa acgagacatc
    41101 gcgaatcgac ggctggcgca gcgacgtcag gttacgcact tccagaatca cttcgcccgg
    41161 cttgttttct ttgtcaggga aacgctggtt aagagaacgc ccaaccatca tggcgatgat
    41221 tttgtccatc gtcagtcctg ccagcggttc ggtagcgatc cactgaccgt cgcgcaatac
    41281 ggtaacttca tcacataact ggaagatttc ttccatttta tgcgagatat aaacaatacc
    41341 gcagccgcgc tcttttaatt tacgaataat agtgaacaga tgattgacct ctttttcggt
    41401 taacgaagaa gtcggttcat ccataatcac aattttcgcg ttataggaaa acgctttggc
    41461 gatttcgatc atctgcattt gcgaaacaga taatgtaccg acgcgcgcac gcggatcgat
    41521 atcaatatcc agttcatcaa aaatcgcttt ggtttcgcgg tacattttgt cctgatcgac
    41581 aaacatgcct ttggtgggat atcgccccag ccacatgttg tccatcaccg aacgttgtaa
    41641 taccaggttt aactcctgat gtaccatcga aataccattt tccagtgctt ctttggcgga
    41701 atggaaatcg atctctttac cctggaataa aatggtgccg gagtcttttt gataaatacc
    41761 aaacaggcat tttaataatg tcgattttcc tgcaccgttt tcccccatta atgcatggat
    41821 agaatgtggc cggactttta agttaacgtt atcaagtgcc ttaacaccag gaaaagactt
    41881 gttgataccg ctcatttcca acaagtattc acctgatgac ggagtcgttg agctgaccat
    41941 ataattttac cttgttggtc atacaataag ggcgcagtaa acgactgcgc ccaatcagtc
    42001 ttatttcttg ctgaattcag ccaggttgtc tttatctacg ccaacataag gtacgcggac
    42061 cactttgttg tcgattttcc agttggtgcc atcagccgca cctttgccat cggccaggtt
    42121 tttcgccaga tcaaaggtcg ctttcgcctg gttgttagca tcgttcagta cggtgcccgc
    42181 cagtgcaccg gatttcacca gcgccagcgc ttctggcagc gcatcgacgc caaacaccgg
    42241 aatgctggac ttgttgtgtg ctttcagtgc ttctaccgcg cccattgcca tcgcgtcgtt
    42301 gttggcgata accacctcga ttttgttggc gttcgggcca gacagccagg cgtccatctt
    42361 atctttcgcc tgagcggtat cccacatagc ggtatctaac tgtaactgtt cagttttaat
    42421 gcctttgtcg ttcaattctt taatcacgta agtggtacgt gcttctgcat ccggatgccc
    42481 cggctcacct ttcagcagta cgaattgaat ctgaccgtct ttgttcagat cccaaccctg
    42541 attcgccgcc cagtgtttag caatcaaatc gccctgaata atgccggact ctttggagtc
    42601 agtgccaacg tagtaggctt tgtcgtagct atccagcgcc ttacgagacg gttctttgtt
    42661 gaagaaaacc accggcacgt tttgcccacg cgctttctca atcaccgtac ccgcagctgc
    42721 cgggtcaacc aggttgattg ccagtgcctt cacccctttc gccagcaata cgtcgatctg
    42781 atcgttctgc ttggactggt cattctgaga atcattcatc agcagctgaa catctggcgc
    42841 ggctttcgca tcttgctcaa tagccttgcg cactacagac ataaagttat cgtcgtactt
    42901 atagattgtt acaccaatgc gagtatcagc agcgtgtgca gcggcaccga ataacatgct
    42961 ggccatcaca gcagacaggg ttaacacctt cttattcatg gtatctccgg tttttcttat
    43021 gcagggtagt gcttgagata aatgctcggc ggggcagtag agttaatgaa gtgttactga
    43081 acgccgaagc tcacttttta aaattcgttc ttccatgccc ggtaacgctc cagaaaacgg
    43141 ctttaattgt tgttatgacg ctattacctc ggtgaaagtg attattcact gttacatatg
    43201 ggttacaacg ttaaaacggt gcaatcatag ccatcacatt gttaagatac tgtgaaatca
    43261 ctcacagatt gaaagcggtt acatcgcctg atttgttgag ttagtgatcg ccgccgcatt
    43321 ctggcgtgtt gcgacagaat ggcgacgcac taacgtcggc ataaaacagt ggctggcacg
    43381 aggatcaata ttgtctgctg ccccctgcaa ggccagttcg gtagctaatt tagccattga
    43441 agcaatggga taacgcacgg tcgttaattg cgggtcggtg taacgggcga tgggaatatc
    43501 atcgaaaccg atgattgaga gatgtagcgg aatcgcaatg ccattatctt ttaatgctgt
    43561 cagtgcgcca gcagccatat tgtcgttata agcaaataca gcggttagtt gtagattgcg
    43621 ccccagcagt tcaaccatcg ccgcctcacc gcccggcatg tccggcgtac cagtgccaat
    43681 ccagctttcc ggcggaataa tatcctgctc tttcaacgca ctcatccagc ctgctttacg
    43741 catggcgtca tcttcaatgc cgtggctgga agaaagataa ccaatacgtt gatgaccgtt
    43801 attcagcaac atgcgcgtcg ccattcgggc accgctgaga ttatccaggc aaacgcaacg
    43861 atgggcgtac cccggcacaa cgcggttgat taacaccata ccaggaatgt tatccataaa
    43921 ttgtgccagt tcatcgtcac tcaatgcttt tgagtgaaca atcaacgcat tacaacgctg
    43981 gcgaattaac acctcaatgg cgtgacgctc tttttccgct tcatgatagc tattgccgat
    44041 tagcacgtat ttctgatgct gctgggcgac cagatccacc gcttttacca gcgcgccgaa
    44101 aaaagcatca gaaacgtcca tcaccaccac gccaatggtg tcgctaacct gagttgccag
    44161 cgcctgggca ttggcgtttg gccgataatc cagctcactc acagctttca ttactgcttc
    44221 acgcgtgtcg gcactgacca gcgtgctgtt attgagcacc cgggaaaccg ttgccacaga
    44281 gacgccagcc tgacgcgcta catcacgaat ggtgatcata ttcactacct gttatgagat
    44341 tgcagtaaat gactgcttgc tggcggctat tttgtcagca ctgaatacag gacttcgtga
    44401 atcgagtcac agcaatggaa acggttacag ccgttttgtt aacgaatgtg atccagatcg
    44461 ttatcttgat gttttagata ttgtcggtcc ggcagcacgc aaagttaact gacgccagag
    44521 ccattccacc ggcccctggc ggaagtaacg cagccagata acagagaaga agatattcgc
    44581 cagccatacc ggaataacaa acgccagcag ctccagacgg tcaaactgca taaacaaact
    44641 gaggtggtaa aaaagcgtag tacaaatcag cgtttgcaat agatagttgg tcagtgccat
    44701 ccgtccgaca caggcgattg ccagcaccag cttaaagcgg cttaattgcg gccagaagcc
    44761 ataaaacagc gacgcatagc caatcgcctg aaacggcgca ctcagttccc gcggcatttg
    44821 aagtaagaag gcacaccagc gatacgccca gtccagctgc cattgcaggg cgatggcagg
    44881 aaggttaatg atcaccccaa tcgccaccag cacaaaacca gtacgacgat agtgacgtaa
    44941 gctgaactgc cctttcagcc agccgctgcg catcagcgcc gcaccaatga gcatcatccc
    45001 tgccagttgc cagccatact gtgcgcccag tgccagtaaa ctgttgccaa caccatcggc
    45061 acgattattg atcgcttcaa caccaccgtg aagcttccag tatttttcat acaaaatagc
    45121 cgatgcatcc ggcgtccagg cgcggctggt ctggctgtcg gaaatcagcc ccaataacag
    45181 caaaacgcca agccccacca gataaagcat gacgcctgta ttaaacaggc tttttaccga
    45241 tggcgcatcg cgcaccagcc gccagcagat taagcccacc agtccgtaag ccagcagaat
    45301 atcgccgtcc cagaacaata aaccgtgaat aaagcccagc aagactaaca gcgttaaccg
    45361 cgactggatc cagcgtctgc cacggggcag caacatttgc aggcccgcac caaacagcag
    45421 cgcaaaaagc gtgaggaatt tcacctggcc gatgagatcg agaaatgccc aggtccatgc
    45481 atcctgcggc gtaatagcgc cgtaccaggc gggattgaga taagccgcct ttggtagccc
    45541 aaaggcgctg atgtttaata gcaggatccc cagaatggcg acgccgcgaa caaaatcgag
    45601 cgtgacgttg cgctccatgg ctcctgcctt ttaatcagtt gtgatgacgc acagcgcgca
    45661 gaaactcgtg gcgcgtattc tgactggatt tgaacaatcc accaagagag gtcgttgttg
    45721 tggcactggt tgcgtcgcgg atgccacgcg ctttcacgca gtaatgcacc gcgtcgatag
    45781 agacagccac gttattggta cccagcagcg tttgtagcgc aatgagaatt tgctgcgtca
    45841 gacgttcctg cacctgcgga cgctgggcaa agaactgcac gatgcggtta atttttgaca
    45901 gaccgatcac cgaatctttc gggatataag ccaccgtcgc tttgccatct atggtaacaa
    45961 aatggtgttc acaggtgctg gtcagggtga tatcgcgcac ggtgaccatt tcatcgacct
    46021 tcattttgtt ttcaatgagg gtgattttcg ggaaattggc gtaatccaga ccggagaaaa
    46081 tttcatcgac atacatttta gcgatgcgat gcggcgtttc catcaaactg tcatcagcca
    46141 ggtcgagatt cagcagctgc atgatttcgg tcatatgacc agcaataagg cttttgcgcg
    46201 tttcgttatc catttcatgc acgggcgggc gcagcggtgt ttccagtcct cgcgcaacta
    46261 acgcttcatg aaccagggcc gcttctttac tgagtgatgg catttatgat ttctcctgca
    46321 ggtgtgacgc ctccgccctg cgtgggggca aagttattaa gctgatttac agcctgatta
    46381 ttgtgcgtga ggcggcgcac ataatccagt attcacagcg ataattattg taattgccgc
    46441 tgcctttcat cagcagatgt taaaacatcg ttatgcaaat acggaagtga aagttactca
    46501 cagcacattg aataaacggt atgatgaaga aattgcaaac aacacaacaa ggagccacgc
    46561 atggaaatgc tcgaagagca ccgctgtttt gaaggctggc agcaacgctg gcgacacgac
    46621 tccagtacct taaactgccc gatgacgttc agtatctttc tcccaccacc tcgtgatcac
    46681 accccgccac cagtgctgta ctggctttcc ggattaacct gcaatgacga gaacttcacc
    46741 accaaggcgg gtgcccagcg cgtggcggcg gaactgggga ttgtactggt aatgccagac
    46801 accagcccgc gcggcgaaca ggttgccaac gacgatggct acgatttagg ccagggcgcg
    46861 gggttttatc ttaacgccac gcaaccaccg tgggcgacgc attaccagat gtatgattat
    46921 ctgcgcgatg aattaccggc actgattcag tcgcaattta atgtcagcga ccgctgcgct
    46981 attagcggtc attccatggg tggtcacggc gcgctgatta tggcgctgaa aaatccgggt
    47041 aaatacacca gcgtttccgc ctttgcgcca attgtgaatc cgtgcagcgt cccgtgggga
    47101 atcaaagcgt ttagcactta tttaggtgag gacaaaaatg catggctgga atgggacagt
    47161 tgcgcgttga tgtatgccag taacgcgcag gatgcaatcc cgacgcttat tgatcagggt
    47221 gataatgatc agtttcttgc tgaccaactg caacctgcag tactggcaga agccgcgcgc
    47281 cagaaagcgt ggccgatgac gctgcgtatt cagccgggat atgatcacag ttactacttc
    47341 atcgcctctt ttatagagga tcacctgcgc ttccatgcgc agtatttact gaagtgaaag
    47401 tccgcccggt tcgccgggca tcttctcatc agaagcgata atccactgcc ataaagtaac
    47461 gacgtccgtc ttcgttatag ctgtagtcgt cacgactgag atccttgtcg ccaaggttca
    47521 gcacgcctgc acgcagtttg acgtctttag tcacctgcca ggccgcgccg gtattccaga
    47581 tggtataacc gcccggtgtt ttagccgtcg cgctgtcggc gcgtttctgc ccggtatagt
    47641 gaccagaaac atagaatgac cagtcttcca gcgccagcgg tttccagtcc agcgtaccgt
    47701 tagcagtatg gaacggcaga tcggatagcg gtttgttttc gccgttgctg acatcacgac
    47761 catcgttgta ggtgtagttg atcgacagtt tccattcatc gttgaacgga attttcagtt
    47821 cggtttccac gccctgaata cgtgctttgt taacgttgta gtagctaaat accggtatgc
    47881 gccgtccgtt agcgcccgtc tcaaaaccga caaagttttg gtagcccggt gcagcgttga
    47941 cgtcagacgt acggctaatg ctgatacgat ctttcacatc gttacggaaa acggtaacgc
    48001 tggattcaac cccttccagc cagccttctt cgcccatgta gtaaagcccc agttcccaac
    48061 tttcgctggt ttctggtttc agatccgggc tacccacaat cttacatgcg ccacggcagg
    48121 aattgctcgt ccagtcaggg ctaagttgca acagagaagg tgctttaaat gccgtcgccc
    48181 agcccccttt caccgttacg gtgtcggtgg cgttataaac caggtaggca cgcggactcc
    48241 agtgttcacc gtaggtttcg tgatcgtcca tacgcacgcc ggtcgtcagc gccagcggct
    48301 cgaagatccg ccattcatct tccacaaaca gcgcgtactg gctggcagac gttttggagc
    48361 tggttccccc ggtcaggttc accgcatcgc taagtttgtc gtgacgccat tcaccgccaa
    48421 ccgtgagaaa ctgattaatc gccgtcagcg gcaacgtgta tttgccgtcg accgtattgc
    48481 tttcggaagt tatcgggctg ctgttgccag ggtttttgtt ctcgactttc tcaccgtagt
    48541 atttcagttc gctggtgccg taatcccaac gcccattatg gctgacggag tagttctggc
    48601 gttccaggcg gtttttgtcc agcgagtcgg aatcacgatc ctgacggtcg aaaccgtatc
    48661 cggcagtaaa atcgtgattt tgattcggtg tccaggcaaa ttcgacattg ccgtcgcggc
    48721 tggagaatcc ttcaatacgc ggcgtttctc cggtatcggt ggtcgttgag ttttgcgggt
    48781 catccttttc acgttttgcc aggctgccgt aagctttcat tcccagcacg ccgtcaatta
    48841 atggtccgct ggtaaagaac tgaccgttat aggtatcacc gcgatcgcga tgttcctgaa
    48901 cggtggtatc gacggtaacg gtgcccgacc atttctgacc gatttttttg gtgatgatat
    48961 tcactacacc gccgagcgca tcggaaccgt acagcgacga catcgggcca cggaccactt
    49021 caatacgttc gatggaatcg accgggatcc agttcagatc gaaatcattg tggcggaaga
    49081 cggcattgcg ggagttaacg cgtttaccgt cgacaagaat cagggtgtag ctgctgtcca
    49141 gaccacgaat acttacgccc ttacggttat ccccttcgtt cgtcagttgt acgccaggca
    49201 cttctttgag gacatccttc agattctgta ccggttttcg ctgcaggtct tcctgggtaa
    49261 tgacgctgat actggcggga gcatctttaa ggttttgttc aacggaagat gcagtgacaa
    49321 ccatcgtttc gccatcatca tcgaccgcta acacaggcca tgcacaagaa atagcggaca
    49381 aacacagccc gacccgtacg aaagggttca acctaaacat tccatatctc catgaggtaa
    49441 ctacgaaaat aaaatgggta tcgctcacat cttctttacg tccccttgcg tacggcagca
    49501 tcgcggtgga cttatttgta tgcaggtgat catcccagaa agccggaaca gcctctgatt
    49561 tgtcagcctt ttttgattgc ggcgtaacga taatgcaaac gataacaatt atcaatccaa
    49621 atgttaaatt ttatatccgc atgatttgtc agggaaatgg aattgaaaaa gccctctcgg
    49681 ttgagagggc ttagcaagga agggaggaaa cttatttctt atcgttctgc gggaacttca
    49741 tttcgctgta gcgtacgaag tgagttcctt taatcagctt atagccgaac caaataatca
    49801 ggaacagcgg gataccaata tacgttgccg ctacgccgcc ccagtcaatg gtatctttca
    49861 ggaacgcttc gtagttctgg cccaaagtga taatcagaca cagaatgaat gcgaagatcg
    49921 gccccagtgg gaagaaacct gaacggtacg gcagatcgtt aatgtcgtgt ccctgcaata
    49981 cgtacccgcg acggaaacga tagtggctaa tggcaatccc cagccaggcg ataaaacccg
    50041 tcatcccgga ggtgttcagc agccacaggt ataccgtctg gttgccaaac atggaggtca
    50101 ggaagcacaa accggcaatc accgtcgtcg catacagcgc attacgcggc acgccaccac
    50161 gcgacagttt agcgaaaatg cgcggcgctt taccgtcaca cgccagggtg tacagcatac
    50221 gagtagacgc atacataccg gagttacccg ctgacagcac cgccgtcaga ataactgcgt
    50281 tcatcaccgc cgccgcagag agcagacccg cgtgctggaa caccagggtg aacggactga
    50341 cgctgatgtc tttaacatcg ttacgcagca ggctcggatc ggtgtacgga ataatcaggc
    50401 tgataatcag gatcgcgaac acatagaaca acaggattcg ccagaatacc tgacgtaccg
    50461 cgcgtggaat gtttttcgcc ggatcttcgg actcgcctgc agcaataccg atcagctcgg
    50521 ttccctggaa agagaagccg acaatcatag ctacgccgat catcgccgca aaaccaccag
    50581 caaacggcgc ttcgccgatt gtccagttgc tccagcccgc aggctgcgcg cctttgaaga
    50641 taccgataat catcagcacg ccaacgatga taaagacaat aactgtcgtg actttgatca
    50701 gtgagaacca gtattccgct tcaccaaagc cgcgaacaga gatgtagttc aacaggaaga
    50761 taacgccgag gaacaacgca ctccagatcc agcccggtgt atccgggaac caccagctca
    50821 tgaccagctg tgctgcaacc aggtcaacgg caatagtcac cgcccagttg taccagtagt
    50881 tccagcccag cgcgaagcca aagccttctt caacatagtt ctgaccgtac gtggcaaacg
    50941 aaccggaaac cggcatatat gcagccagtt caccgagact ggtcatcagg aagtaaacca
    51001 tcaggccaat cagcatatac gagagcaatg ccccgcccgg acctgcctga gaaatcgttg
    51061 cgccagaggc aacaaaaaga cctgtaccga tggaaccgcc aatggcaatc atcgtcaggt
    51121 gacgcgcctt caattcacgg cgtaagcccg gcgcttctgt agttttagtt tcggaaccca
    51181 tacaaaaatg ctatccatct taaaaatgag gcgcgattgt agcagacgat tggcaatcct
    51241 tccggcagaa atacacggtt ataagacacc ttcatgatcg cccagggatt ataagtaaag
    51301 cagccaatct cttttctggc gaatgcatgc tgagggcgct gcgtcacgaa atcgacacag
    51361 caccagcatg ttcttgtaca gcaccttaac gcggtacatt cgcgggatcg caatagtcca
    51421 gaaagcgccg tagcgcgttg gaaaggtgtt tttgccgatg atgtatacgc cacaacgtac
    51481 gcatcaggcg cggcagaggg accgcaactt cacttaatgt gcctgcctgc aattgatctt
    51541 caatcacccg tcgcgacagg caactaattc ccaacccatg acgcaccgca tgtttgattg
    51601 cctcggagtt acctaattcc atcgccatct caaacttcgg taaatgtgac agcaacagat
    51661 aatcgacaat ctcccgcgtg ccggaaccgc gttcacgcag gatccacggc gcagcggcca
    51721 gctgttctaa ggtgaccgga ccacgagcca acggcgaagt cggcgcggcg aaaaccacca
    51781 gctcgtcttc cagccacggt tcagaaatga tttcagtgct gtggcacggt ccttcaataa
    51841 agccaatatc aacgcggaaa tccagcaccg cttgcatcac gtcctggcta ttcccaacgc
    51901 taagttcaat cggcaactgc ggataatcat ggcgataacg ggcgataact gcaggtagaa
    51961 tgtagttacc gatggtacta ctggcataga tacgaatcgc gccgttgtct tcgcgaaaca
    52021 gttgttcgat ttcaaccgcc tgttcaagca gtgccaacgc tcgcggatag agcagccgcc
    52081 cgtgttcatt aacaaccagt cttttcccca cgcgatcaaa cagttgaacg ccaagctgcc
    52141 cttccaggtc ggtcaaggct gcgctcactg ctgattgcga caacgccagc atcaccgacg
    52201 cctgggtggt tgatccactt ttcaatactt ctgcaaaaac ttccaactgc cggagggtga
    52261 tgtgcatagt cgcttaccac ttataaagat taattataaa tatataatca attttatttt
    52321 taaaccagtt agtcgtaacc ttatgcccgg ttaaaggaga gggttatgac gaatatcacc
    52381 ttacagaaac aacatcgtac actgtggcat tttattccgg ggttagccct gagtgcagtt
    52441 atcaccgggg tcgccctgtg gggtggttcc attcccgcgg ttgcgggtgc cgggtttagt
    52501 gccctcaccc tcgcaatctt gttggggatg gttttaggca acaccattta cccgcacatc
    52561 tggaaaagct gtgacggtgg tgtgctgttt gccaagcaat atttattacg tctgggtatc
    52621 attctttatg gcttccgtct gacgttctcg caaattgccg atgtcggtat cagtgggatc
    52681 atcattgacg tgttgacgct gtccagtacc ttcctgctgg cttgcttcct ggggcagaaa
    52741 gtgtttggtc tggataagca caccagctgg ttgatcggtg ccggtagcag tatctgtggt
    52801 gctgccgcgg tactggcgac tgagccggta gtgaaagcag aagccagtaa agtaaccgtg
    52861 gctgttgcaa ccgttgttat cttcgggacc gtcgcgattt tcctctaccc ggcgatatat
    52921 ccgctgatgt ctcaatggtt tagtccggaa actttcggta tctacattgg ttctactgtg
    52981 cacgaagtgg cgcaggtggt ggcggcaggt catgccatca gcccggatgc agaaaacgca
    53041 gcagttattt ccaaaatgct gcgcgtgatg atgctggctc cgttcctcat cctgctggcg
    53101 gcgcgtgtta aacagctgtc tgggacgaac agcggcgaga aaagcaaaat cactattccg
    53161 tggtttgcca tcttgttcat cgtcgttgcc atctttaact cgttccacct gttaccgcag
    53221 agcgtggtga acatgctggt aacgctggat accttcctgc tggcaatggc gatggcggcg
    53281 ctgggtctga ccactcacgt cagcgcgctg aaaaaagccg gggcgaaacc tctgctgatg
    53341 gcactggtac tgtttgcctg gctgattgtt ggtggtggtg cgattaacta tgtgattcaa
    53401 agcgtcatcg cataaaccac tacatcttgc tcctgttaac ccgctatcat taccgttttc
    53461 ctccagcggg tttaacagga gtcctcgcat gaaatacatt ggagcgcacg ttagtgctgc
    53521 tggcggtctg gcaaatgccg caattcgcgc cgccgaaatc gacgcaaccg cgtttgcctt
    53581 gttcaccaaa aaccaacgtc agtggcgtgc cgcaccgctc acgacgcaaa ccatcgatga
    53641 attcaaagcc gcctgtgaaa aatatcacta cacatcggcg caaattcttc cccacgacag
    53701 ttatctgatt aacctcggac atccggttgc tgaagctctg gaaaaatcgc gcgatgcctt
    53761 tatagatgaa atgcagcgtt gcgaacagct ggggctttct ttgctcaact tccaccctgg
    53821 cagccatctg atgcagattt cagaagagga ttgccttgcg cgtattgccg aatccatcaa
    53881 cattgcgctg gataaaactc aaggtgtcac cgcggtgatt gaaaacaccg ccggtcaggg
    53941 cagtaactta gggtttaaat tcgaacatct cgcggcgatt atcgacggcg tggaagataa
    54001 atcccgcgtc ggcgtctgca ttgatacctg ccatgctttc gctgccgggt atgatttgcg
    54061 tactcctgcc gaatgcgaga aaacgttcgc tgattttgcc cgtattgtag gctttaagta
    54121 tctgcgcggg atgcacctca acgatgcgaa aagcaccttt ggcagccgcg ttgaccgtca
    54181 tcatagcctc ggcgaaggca atatcggtca tgatgcgttc cgctggatca tgcaggacga
    54241 ccgtttcgac ggcattccgc tgatccttga aaccatcaac ccggatatct gggcagaaga
    54301 gatcgcctgg ctgaaagcgc aacaaactga aaaagcggtg gcctgatcga tgaacgacag
    54361 ggaaaaacag attcttaaaa ttttacggcg taacccgctg attcaacaga atgaaatcgc
    54421 cgatattctg caaatcagcc gctcacgtgt tgccgctcat attatggatt tgatgcgcaa
    54481 gggtttgatt aaaggcaaag gatatatcct taccgagcag gattactgtg tggttgtggg
    54541 tgcaatcaat atggatattc gcggaatggc ggatatccgt tacccgcaag cagcctctca
    54601 tccaggttct gttcactgtt ccgcaggcgg cgtcggacgt aatatcgcgc ataacctggc
    54661 tctgcttggt cgggatgtgc atttaatttc agctattggc aacgattttt acggcgagac
    54721 attactggaa gaaacgcgcc gcgcgggcgt gaacgtttca aactgcattc gtctgcatgg
    54781 acacagcact gcaacttatc tcgctatcgc taataagcag gaagaaacta tcctggcaat
    54841 caatgacaca cacattctgc aacagctaac gcctcaactg ctcaatactt cacgggactt
    54901 gattcgccat gctggtgtgg tgctggctga ttgtaatctc acacctgaag ccctggagtg
    54961 ggtctttacc attgctgatg aaattccgat gtttgtcgat accgtttccg aatttaaagc
    55021 gaacaaagta aaaaactggt acagccggat ccacactctg aaaccaacac aaaatgaact
    55081 ggaaattttg tgggggcaac cgattaaaga cgacaacgat cgcatcagag ctgtaaattc
    55141 gctgcatcaa caaggtgtta aacgcatttt tgtttatctg aaagatgaat ctgtattttg
    55201 cagcgataag gatggagaac aatttttgct gaccgcacca gcgcatacga cagtagacag
    55261 ttttggtgct gacgatggtt ttatggcggg cctggtatat agctttcttg aaggatacag
    55321 tttccgcgac agcgcccgtt ttgcgatagc ctgcgcggca atttcgcgtg ccagcggcag
    55381 cttaaacaac cctaccctgt ctgccgataa cgcgctttca ttagtgccaa tggtgtaaca
    55441 atgttgccgg attcgacgct tgaccgcatc ttatccggct cataaattgc gcactacgct
    55501 aaaccaataa agaatcctgc aatagtagca ctcatcaggt tactgacagc aaaaacgcaa
    55561 tagccagcaa taccaccatt cccagaacac ttctcatgac atccatagtt attatctctt
    55621 catgtcattt tgggcgacgg ctctctgccc atcataaata gccgggcctg catcttgcga
    55681 tactgacccg gcttgttatc aacacttaat gggttttgat gtagccgcgt acgcactctt
    55741 cgactaatcc ccagaaccag tctgtatcaa tagtgatgcc gactttggta ttggcgggct
    55801 tgccaagaac gcccaactcg tcgcagacgg tacgcccata gcaagggcca ctgttaacgt
    55861 ccacttcgac gtacatctcc tgggttttaa tgccatcagg gttaatcaaa taaccgatgc
    55921 aggtggcgtc gtgcaccggg ccgccagcca ggccgtagtt ttcgaactgc gttttgagag
    55981 tgaagttcat gatgtcgctg aacagctctc ccgcagggcc gccagccctt tccatccgag
    56041 caatcacgtc cggggtgcaa acggtctggt tggtaagatc gaggcccatc atcactaatg
    56101 gaacgccgga ggtgaacacc acgcgtgcgg cttccgggtc agcaaagata ttgaactcag
    56161 cagatggggt gaagttgcca gtaccataag cgccgcccat cagaacaatt tcacggattt
    56221 tcggcaggat cgcgggttgc atacgcattg ccaccgcgat gtttgacaac ggaccaaccg
    56281 gcaccagagt gatatcgcca tcgcttgcca taagggtatc gatgatatat ttcaccgcat
    56341 gagtgttttc tgcctggcgg gtcagcggct cgaataccgg gccatccagt ccggtttcac
    56401 cgtgaatatt atcggcaaca atttgttgac gcataatggg ctgcggcatc cccgcataaa
    56461 ccggaacatt aatctccagt ttctggcaaa cattcaggcc attaattaat gttttatcga
    56521 gggtttgatt acccgctaca atggtgatac ctaataaatc aatcgcagga tgtttcgccg
    56581 ccatcattat agcaatagca tcatcatgac ccggatcaca atccagaata atttttctct
    56641 tttccattgt ttatttcctc tgtttccagt tgcgttattg tttctacagc aaagaaaatt
    56701 cgacctggcc gatgattgaa tcttaacaac agcgtacgta tgctaaatat gagaaatctc
    56761 atagcggata aacatcgtga aagaaatcca caataatgat cttaagcagc aattgatgag
    56821 tgaatctgcg tttaaggatt gcttttcaac ggatgtttca gccgatacgc ggctgtttca
    56881 ttttttagcg cgtgactaca ttgtgcagga agggcaacag ccgtcctggc tgttttacct
    56941 gacgcgaggc cgcgccaggc tttacgtcac gcttgctaat ggtcgcgtgt cgctgatcga
    57001 tttctttgcc gcgccctgtt ttattggcga gattgagtta atcgacaaag accatgaacc
    57061 gcgtgcagtg caggctattg aagagtgttg gtgccttgcg ctccctatga agcattaccg
    57121 cccgctgtta ttaaacgaca cgctattttt acgaaaactc tgcgtcacct taagtcataa
    57181 aaattatcgt aatattgttt ctttaactca gaatcaatca tttccgttag tgaatcgcct
    57241 ggcagctttt atattactct cgcaggaagg tgatctttat cacgaaaagc atacgcaagc
    57301 ggcagagtat ttaggcgttt cttatcgaca tcttttatat gttctcgcgc aattcattaa
    57361 tgacggttta ttaattaaaa gcaagaaagg gtatctcatt aaaaacagaa agcagttgtc
    57421 aggactggcg ctggagatgg acccggagaa taaattctcc gggatgatgc agtaaaaatt
    57481 attggcaata gtgcgattgc cggatgcaac gcttaataag gcgtacatcc ggcaatgaaa
    57541 ctcaagctaa accaataaag aacccggcaa tggtcgcgct catcaggttg gaaagcgtcg
    57601 ccgccgccag cgcccgtaaa ccaagctggg cgatttccgg cgcgcgtttt ggcgaaatag
    57661 ccgaaaacgc tccaacgaca acaccgatag aaccaaagtt agcaaaccca cagagggcga
    57721 acgagataat ggcaatggtc ttgacatcca gcgtgccgct cgtttgcaga tagggcgaga
    57781 aattgagata agcaacaaac tcattaatcg ccaatttctg cccaatcaaa cttccggcaa
    57841 gatttgcatc actccagtcc acccccataa tccatgccaa cggggccagc acatagccga
    57901 aaatgctttc cagagagaca ttggcaaaac caaaccagcc gccaactcca ccaataatgc
    57961 cgttgatcag cgcaatgatc gccacaaatg ccattaccac cgtcgccaca ccggcggcga
    58021 ttttcagccc ggtcattgca ccgttcgccg cagcttcaat aatgcttttt ggcggtgttt
    58081 cgctaaacga cagattttca aacgtaactt gcgaaggttc cgtcgccgga ctaagaatac
    58141 gtgcaaacag gataccgcca ggaatagcca tcagcgaagc ggctaacaaa tagtcaatcg
    58201 gcacgcccat tccggcatag ccaatcatca tcgaacccgc aatagacgcc atgccgctac
    58261 aaatagccgt aaatagctcg ttgcgattca tgcgatcaat aaaaggttta acgatcgccg
    58321 ggatctcatt ttgcccgagg aagatagtgg tgactgcgac aaaagattcg attttgctga
    58381 tgttgagggc tttctgaaaa atactgccaa gaatacgaat cagcagcccc attacgccaa
    58441 tgtagtacag caagctgata agcgcggtaa cgaaaataat cgccgggagt acgcgaaagg
    58501 cgaagataaa gcccgcaccg tcaaacagaa catccatttt gggaccgacc agcgaaccaa
    58561 aaataaaggc acttcctgcg tcactgtagg acatcacttt atggacgcct aatgccgcct
    58621 gctctactgc ccattttccc gggggaaaat agagcatgat gccaccaatg gcaatttgca
    58681 gcagcagcgc agccccaacc gtgcgcaagc tgatgctctt tttatttacc gacaacacaa
    58741 aggcaattgc cagcaatacc accatcccca caacacttct cattatatcc ataatgattt
    58801 tcccttcatg ccagtaaacc cggcgtcagc gccaggtttt ggtatgtttg atgagtacgg
    58861 gcgacggctt tctgcccacc agaaattaac ccacgagacg ctgatattct ttggcaattt
    58921 cgctcgccag aatggcgtta ttaaagacca gttgaatatt ggatttcagg ctatcaccgc
    58981 cggttagctc cgcaacacgc gccagcagga acggtgtact ctctttccca ataacaccct
    59041 gttcttcggc ttcagcaacg gcttgatcaa ttgctgcatt gatggtttct tctggcatcg
    59101 caaactgttc cgggatcggg ttcgctacca ccaggccgcc gttcaaaccg gtttgccact
    59161 tcactgccat cgcgcgagca atttcgcggg cactgtcgag acgaatgctg acatcaaatg
    59221 ggctggttcg gcagaaaaac gcaggcagcg cttttgtctg ataaccaatt aacggtacac
    59281 cgaaggtttc taaatattct gttgttaatc ctaaatcgag aatagatttt gcccccgcac
    59341 aaacaacagt gacattggta tttgccagtt cctgtaaatc ggcagaaata tcgaaggtat
    59401 gttccgctcc gcgatgcaca ccaccaatac ctccggttgc aaaaacttta atcccagcca
    59461 gtgctgcaat aatcatggtt gatgcaacgg tagtcgcgcc atttttccct gcagcaacga
    59521 caaaaggtaa atcacgacga ctaactttcg tcacgttatg tccttcacgg cccagcaatt
    59581 cgatttcttc tttacttaag cccactttca tcacaccgcc aataatggcg atagtggctg
    59641 gtactgcgcc ctgtttacga attgtttctt ctacttcaat tgcggtttgg gcattttgtg
    59701 ggaatggcat tccgtgagaa attatggtcg attccagcgc aacaaccggt tttttatttt
    59761 ttaaagcatc ctgtacttca gcggatattt gtaataattc aggggacaga gttaattcag
    59821 acattctgtg ttctccacta acgatgtaac attggcaatt gataattcag ggttgttggt
    59881 atattcacag gcaagtgcca ttgacgaaca tccctgcgca aatcgaacag aatcgataaa
    59941 cggcataccg tctacccaac aggaggccag ccccgccatc atggcgtcgc ctgccccagt
    60001 aacattgatg acattcgttt taataggggc cgaccaccca ctttcaccgt tgatatcact
    60061 gtagtaaacg ccatcccctc ccatgctcag caccaggcgg ttcaggccgt gttgatgaaa
    60121 ccaggcggcg acctttgcga catcttcacg tccggaaagt gcaattccgc tcaacgtttc
    60181 ggcttcaaga cggttaggtt ttaacgtatg gattttgctc agatgatcgc ggattttgac
    60241 gcatttccat gccgataccg gatcaataaa tacaggcgtt tccccgctat tttccagaac
    60301 ccagaccagc gcctcttcac taaggttgca atccgcgaca ataacctttg caccgcgaat
    60361 aaactcctga tgctgggcaa gaaattctgc agaaatacag tcactaatac tcatatcatt
    60421 tatcgcgaca agcatttctc ctgtattatc gagcagtgat aaatagctgg atgtattctc
    60481 acccggaaca attaagcatt tatcgacata aacaccggat tgattagttt gcgccagtaa
    60541 tgattgccca taaaaatcac cacctactgc acttaaaagc caggcatttt tccccagtaa
    60601 cgccagatta tgagcgatat tccttcccac gccacctggg gtaaatttaa tttttccggg
    60661 attcgaatcc gcataattca atggatgatg tgaataccca gccacatcaa tattcgccga
    60721 gccaataatt actatgtagt ccttttcgcg catagcacgc cccctggcaa taaattgcca
    60781 acgaagaaat tgggtaaaat agtcattaca gtcaataaga ctattagagc atgtgttcag
    60841 atttaaacac atgttcataa taagcatgtt taacgtaatg taaatcgatc agaaaaaacg
    60901 aaatcggcca gatatgaagg cggtcacaaa atttgtctat ttatgcagca acaaaagaga
    60961 aagttgtgat gtgtaacaca caatatggca ggcaagaaaa agggcagaga tgtttctgcc
    61021 ctcagattgt tgacaatgcg cgctttgttc atgctggatg tggcgtaaac gccttatccg
    61081 acctacaaaa gcgcaaaaat tcaatatatt gcagggttca tgtaggtctg ataagcatag
    61141 cgcatcaggc aattttgcgt ttgtcatcat cggggcagag atgtctcatc cccgatgatg
    61201 aagagaaatt atgcgttttt ttctactatt tgtgtttccg ggcgtttgag gaaggcatag
    61261 gccaaacccg ccaccagcgt accggcaata attgctacca ggtaacccaa taccggcgta
    61321 atagcgccag ggatcagcag aacaaacaga ccaccgtgcg gagccatcag tttcgcacca
    61381 atcgccattg agattgcgcc agtcagcgcc ccaccaacga tacagcacgg tagcacacgc
    61441 atcggatcac gagcagcaaa cggaattgca ccttccgaaa taaagcacag accaagtacc
    61501 agagcggctt tgccaccttc ctgctgcgct ttatcgaatt tacgacgcgc caccattgtt
    61561 gccagaccca ttgccagcgg tggcaccata cctgccgcca taatcgccgc catcgggcca
    61621 taggtttgag tactcagcag acccacaccg aatgcgtacg ctgctttgtt taccggaccg
    61681 cccatgtcag tacacatcat gccaccgagg atcgccccca gcagaaccgc attcgcagtc
    61741 cccatggtct gcagccagtg agtcaaccca tcgagaatgc cagcaaccgg tttaccgatt
    61801 aggtagatca tcgccagacc gaccaccaga ctggaaatta gcggaatgat caggatcggt
    61861 ttcagtgcct ccatactctg tggcagtttc agttgcgtac tgattaactt cgcaatgtaa
    61921 cccgccagga agcccgcaat aataccgcca atgaagccag aaccggtgct aaccgccagc
    61981 ataccgccaa tcagacccgg cgtgagaccc ggacgatcgg caatggagaa ggcaatataa
    62041 cctgccagta ccggcaccat cagcgcaaag gctgaaccac caccaatctg catcagcgcc
    62101 gctgccaacg tacccggctc tttaaacgct tcgataccaa aagcaaaaga aagcgcgata
    62161 cacagaccac ctgcaacaac catcggcagc atgtaagaga cgcccgtcag caagtgacgg
    62221 taagcgcctg cactctcttt cttaccttca gtggtcgctg tttgagcttt gcccgctggt
    62281 tcatacggcg ttgcttcagc aaccgcttta tccagttcct gcgcagtttt cttcagcgcc
    62341 agaccggtag aggtgcgata catcggttta ccagcaaatt tcgccagatc cacttcgata
    62401 tctgccgcca caatcaccag atccgctgct gcgacttctt caggtgtgat tgcattaccc
    62461 gcgccaacag aaccacgggt ttcaactttc acccaccagc cacgtttttt cgcttcggtt
    62521 tcaatggctt cagccgccat aaaggtgtgt gctacaccag tcgggcaagc agtcaccgca
    62581 actacgcgtt tcggaccgct agcagcaacc ggtgctgtcg cagcgaccgg cgcagtgtaa
    62641 ggtttcgcat ggcctttggc ttcactcagg aacagctcag ggtgcgcaac tgcccgggaa
    62701 atatcgccca gccagacatt tttaccgttc agcgcgctgt cattcgggat gaaatcaccg
    62761 agaacaatcg ccatttctgc gtcgttcgga ttgtcgatga tttccagttt tgcttttcgc
    62821 gccgccgcgc ccagcagggt cttcgccata taggcgcgtg cctgaccgag attagcgtca
    62881 ataatcagca gcgttttcat tatgcctctc ctgctgtcag ttaaaaggtt gtaagtcgac
    62941 gcgcgccatc attgcggcca actgcggacg atcggtaata cccacattgc tttgacttac
    63001 cgccagggct gcaacagctg tcgccagacg cagtgtgtgt tcactggatt cacgcatcag
    63061 caagccataa atcaggccac caaccataga atcccctgcg ccaacggtgc ttacgacatc
    63121 gactgacggt ggtttggcga tccattcgcc ggaggcatta acccaaagcg cgccttcggc
    63181 acccagtgaa ataacaacat gcgcaatacc ttgttcacgt agcgcatgtg cagcttcaat
    63241 cacatctttc atttcaggca gtttacggcc tgcccagatt tccagctcgc ggcggttagg
    63301 tttcaccagc cacggtgccg ctttcaaacc tgctactaac gcttcacggc tactatcaaa
    63361 gataatgcaa ggacactgac tacgcaggcg agtcatccag tcggtgaacg cttccgggct
    63421 gacgcctgac ggtaagcttc cgctgacaca gaccatatcg aactgaccga gccagctcag
    63481 agaatcagtc acaaagcgtt cccagtcggc gggggtaact tcaaaacccg agaagttgaa
    63541 gtcggtcact tcgccgtctt tttccgtcag cttaacgtta attcgggtgc gcccctgtac
    63601 aacctggaaa cggttggcaa tgcccagctc gctgaacagt tgctgaaaac catcctgatt
    63661 gtctttaccc aggaagccgc caacggtgac atcaattccc aggtctttta atactttggc
    63721 cacgttgatg cctttacccg ccgcatgcag accggtggtt ttcaccaggt tcacttcgcc
    63781 gcgttcaatt tccgggcaga aaccaacaag gtcataagcc ggattaaggg tgatcgtagc
    63841 aacacgtctg ctcattatgc gccctcccca agaccagcag cgatagcgtc gccaatggct
    63901 ttcagcgcct gttcagcatc tgcaccctgg gcggtaaagc gtaggcgatg acctttctta
    63961 acgccaagtg ccacaacttt catcagacta cgtccgtttg ccggtttgcc ggtgccatca
    64021 aggtttgtca cggtaatatc actgttaaat tgtttaatgg tattgaccag catggtacct
    64081 ggacgagcat gcaggccgtg ttcattgcgc accacaaact ccgcgcttaa cacgtcgtcg
    64141 gtcggcgcat catcgctggt cagcagcgcc agcaacgttg ccgcatccgc tttcagcaag
    64201 cggtcagctt tattatcgag caacaaatca gcgagacgct taagaaccgc gatgggctga
    64261 tcgtcattca ttgccacact caccagcatg gctgccgttt cgccgtccac atcaaaagca
    64321 tttgccgcac ggcttaccgc aatcgcgcta cgcagattgc cttcggcgct atcgctcagc
    64381 cagataccct gtccgaggtt cagcggttgt tcattgatgg ctttggtgac gaaagtggcg
    64441 tcaactgccc ccgcttcttt cagacgcgca gcgttcagcg cctgaagagt cagcagatcg
    64501 ctggcgacga tatccagcgt cagcatttcg ttgtcgagct tcagctgctc actctgcttt
    64561 tcgcccatca gcaatgcgcg aagttcttct gctgttgttg ctgacttcag ttgttcagca
    64621 acggaatcat cgctcagtac gtgggtcagc tggcgtagca ggcccagatg ttcatccgag
    64681 ctggcagcaa taccgatcgc cacgtacgct acctggccgt ccccccaggt gacgccttcc
    64741 gggaactgaa atacctgaac gccggttttc agcacctgat cgcgggtgtc ggtagtgccg
    64801 tgtggaatag caataccatt gccgaggaac gttgaggttt gctgttcgcg cgccagcatg
    64861 ccattgacgt agccttcagc tacattaccg gcctgcacca gcgccgcagc gacctggcga
    64921 atcgcctctt ctttgtctcc ggccttttcg cccggatgga tgtcctgtac agataactgg
    64981 aacatagttc tcctctcttg ctgaattgaa acgattcagc ttctatgaga aaaaaagcgc
    65041 caacctggct tagggttaaa gacaagatcg cgctgaaacg tttcaaggaa gcataatact
    65101 tctgtttcag cgcgcaagga aagccgtaaa gttatgagca aaagtttgat gtgctgcaca
    65161 attttttgtc atttttccta attgctgatg ggaaaatccg ttatcagcaa tttcatttca
    65221 gcagtgtcag cagccaatca gcaacagtga aatggcattt tgattattcg tggcgctttt
    65281 gatttcgctg tctgtttatt ttctgacaag cagcgtaaac tccgcgtctt cctcttccag
    65341 tgatcgacca gcatgcataa ctcccccaca gtcaccagcg cgaaatcgtt tgacctgacc
    65401 tcgacggcgt ttttaatcgt tgcctttctc accggtattg cgggcgctct gcaaaccccg
    65461 acactcagta tttttcttac tgatgaagta catgcccgtc cggcgatggt gggattcttc
    65521 tttaccggca gcgctgtcat tgggattctg gtgagtcagt ttctcgccgg gcgctctgat
    65581 aagcgcggcg atcgcaaatc gctgattgtc ttttgctgcc tgttaggcgt gctggcctgc
    65641 accctttttg cctggaatcg caactacttt gttttgctat tcgttggcgt ctttcttagc
    65701 agctttggct cgaccgctaa cccgcaaatg tttgcccttg cccgtgaaca tgctgacaaa
    65761 accggacgtg aggcggtgat gttcagctct tttttacgcg ctcaggtttc actggcatgg
    65821 gtcattggcc caccgctggc ttatgcctta gcgatgggtt tcagctttac ggtaatgtat
    65881 ctgagcgcag cggtagcgtt tattgtttgc ggcgtgatgg tgtggctgtt tttgccgtcg
    65941 atgcaaaaag agcttccgct ggcgaccggc acggttgaag cgccgcgccg taaccgtcgc
    66001 gatacgttgc tgctgtttgt catttgtaca ttgatgtggg gctcgaacag cctgtacatc
    66061 atcaacatgc cgctatttat tatcaacgaa ctgcatcttc ccgagaaact ggccggtgtg
    66121 atgatgggga ccgccgccgg gctggaaatc ccgaccatgt tgatcgccgg atattttgcc
    66181 aaacgtctgg gtaagcgctt cttaatgcgc gttgctgccg tgggtggcgt ctgtttttac
    66241 gcaggaatgc tgatggcgca ttcacctgtc attctgttgg gcttgcagct gctaaatgct
    66301 atttttattg gcattcttgg cggcatcggg atgctctatt ttcaggattt gatgcccggt
    66361 caggcaggtt cagccaccac gctctatacc aacacttcgc gcgtgggctg gatcatcgca
    66421 ggatcagtgg cgggcatcgt cgccgagatc tggaattatc acgctgtgtt ctggtttgcg
    66481 atggtgatga ttatcgccac tctgttttgc ttactgcgaa ttaaagatgt ttaaggcgcg
    66541 gtcaacattt ccagatcgat aagccagatc atggcctgct gacgcgagtt accgcacatt
    66601 tcagcgctgg cttgtaagcc tgcacagact ttcggtcgca gtggcgaggt gaaaatttta
    66661 cagcgttgct gttcatcaag ctgaatgcag ggagtattgg cgggcttgcc atctggcata
    66721 ccgggaatag ggctggaaat tgaaggggca gtgcaacacg ccccgcaacc cggacggcat
    66781 tccatacgtt gttctcttaa ggttaaccac cggattgatg agcgcgcaca gtaccacctt
    66841 ttttgcacca gcaaaagtgc gaataccact tgcccgaaag gcccgtcgcg agtactttgt
    66901 cgcgatattt ttgacatttt tgactacagg aatttttcga tgccaagagc gaacgaaatt
    66961 aaaaaaggta tggtactgaa ttacaacggc aaactgctgc tggttaagga cattgatatt
    67021 cagtcgccca ctgcccgcgg tgccgctacg ctgtacaaaa tgcgtttttc tgatgtccgt
    67081 accgggctga aagtagaaga gcgtttcaaa ggtgatgata tcgttgacac cgtgacgctg
    67141 acccgccgtt acgttgactt ctcctatgtc gatggcaacg aatatgtctt tatggataaa
    67201 gaagactata ccccgtatac cttcaccaaa gatcagattg aagaagagtt gctgtttatg
    67261 cctgagggcg gcatgccgga catgcaggtg ctgacctggg acggtcagtt gctggcgctt
    67321 gagctgccgc agaccgttga tctggaaatc gttgaaactg caccaggtat caaaggggca
    67381 tctgccagcg cccgtaacaa accggcgaca ttgagcactg gtctggtgat tcaggtacca
    67441 gaatacttaa gcccgggcga aaaaattcgt atccatatcg aagaacgccg ttatatgggt
    67501 cgtgctgact aacttcagcc gcatgcagaa aagggatagc tcaggctgtc ccttttttaa
    67561 tttattatac caatcttcta ttttgcgctt cctgaacacc ttacgcccgc aattttcact
    67621 cgttgattga tcgccctcac acttcatcgc attaacaatc cagaccaatt tcaattgctg
    67681 tcatataact ttacactgtc attgttaatt aatcgttact aagacgtgac tcctatgaat
    67741 acaatcgcct ccgttacgct cccgcatcat gtacacgctc cacgctacga tcgacagcag
    67801 ttgcaatcac gtatcgttca ttttggcttt ggagcctttc accgcgcaca tcaggcatta
    67861 ctgaccgatc gtgtgctgaa tgcccagggc ggcgactggg ggatctgtga aatcagcttg
    67921 ttcagcggcg atcaactgat gagccagctc cgcgcacaga accatttata taccgtgctg
    67981 gagaaaggtg cggacggcaa tcaggcgata attgtcggtg ccgttcacga atgtctgaat
    68041 gcaaaactgg attccttagc ggcaattatt gagaaatttt gcgagccaca ggtggcaatt
    68101 gtttccctga caattaccga aaaaggctat tgtattgacc cggccaccgg tgcactcgac
    68161 accagcaatc cgcgtattat tcacgatcta caaaaccctg aagaacctca ctccgcgcca
    68221 ggtattctcg tcgaagcact gaaacgccgc cgtgagcgcg gccatacacc gtttaccgtg
    68281 ctctcctgcg acaatattcc cgacaatggc catgtggtga aaaacgcggt gctgggaatg
    68341 gcagaaaaac gttcgccaga actcgccggg tggataaaag aacacgtcag ttttccggga
    68401 accatggtcg accgcattgt tccggctgca acaaacgaat cactggcgga aataagccag
    68461 catctggggg tgaatgatcc ctgcgcgatt agctgcgaac cgtttatcca gtgggtggtt
    68521 gaagataact tcgtcgctgg gcgtcctgcc tgggaagtcg caggtgtaca aatggtgaat
    68581 gatgtcctgc catgggaaga gatgaaactg cggatgctta atggcagcca ctcttttctc
    68641 gcttatctgg gttacctctc aggattcgcc catatcagtg attgcatgca ggatcgcgca
    68701 tttcgccatg ccgccagaac attaatgctg gatgagcaag cgccgacact gcggattaaa
    68761 gatgtcgatt taacacaata tgcggataag ttaattgcac gttttgctaa tccggcactg
    68821 aaacataaga cctggcaaat cgcgatggat ggcagccaga aattaccgca acgcatgttg
    68881 gcaggtattc gcatacatct ggggcgcgaa acggactggt cgttgctggc attaggcgtt
    68941 gcaggctgga tgcgttacgt cagcggcgtt gatgatgccg gaaatgccat tgatgttcgc
    69001 gatccgctta gcgataaaat tcgtgaactt gttgcaggca gcagcagtga acaacgcgta
    69061 accgccctgc tttccctgcg tgaaattttc ggtgatgatc tgccagataa cccgcatttt
    69121 gtgcaggtca tcgaacaagc ctggcaacaa atcgcacaat tcggcgcgca tcaggcgcta
    69181 ttaaacaccc tcaaaattta acgatttctg cggttaaagc ggatgaagct cgccttcgtc
    69241 cgctctcccc ttctcttttc tgcctttttt agccaggatt aacgctcagt taacttacca
    69301 gagtattgcg gagccgttgt gaccagaacc aacctcatca ccggttttct cggcagcggg
    69361 aaaactacgt cgattcttca tctgttagcc cataaagatc ccaacgaaaa atgggcggta
    69421 ctggttaatg aatttgggga agtcggaatt gatggtgctt tgctcgccga tagcggcgca
    69481 ctgctgaaag agatccccgg cggttgcatg tgctgcgtta atggtttacc catgcaggta
    69541 gggttgaata ccttactgcg tcagggaaaa ccagaccgct tgttgataga gccgaccggg
    69601 ctgggccatc cgaaacagat cctcgatctc ttaaccgcgc cagtctatga accgtggata
    69661 gatctgcgcg ccacgttgtg cattctcgat ccacgcctgc tgctggacga aaaaagcgcc
    69721 agcaatgaaa acttccgtga ccagctggct gccgcagaca ttattgtcgc caataaatcc
    69781 gaccgtgcga cgcccgaaag tgagcaagcg ctagagcgct ggtggcagca aaatggtggc
    69841 gatcggcaat taattcacag cgagcatgga aaaattgacg gtcatcttct ggatttgccg
    69901 cgtcgcaatt tagccgagtt gcccgccagc gccgcgcatt ctcatcagca tagcgtgaaa
    69961 aaagggttag cagcgttaag cctgccagag catcaacgct ggcgtcgcag tctgaacagc
    70021 ggacaagggc atcaggcctg tggctggata ttcgacgctg atacggtatt cgacaccatt
    70081 ggtattctgg aatgggcgcg acttgcaccg gtggaacgcg tcaaaggcgt gctgcgtatt
    70141 cccgaagggc tggtgcgaat caaccgtcag ggcgatgacc tgcacattga aacgcaaaac
    70201 gttgcgccac cggacagtcg tattgagctg atttccagca gcgaagctga ctggaatgcc
    70261 ttgcagagcg cgctgttgaa gcttcgttta gcgactaccg cgtaaggttg cctgcgtttt
    70321 tcagtaagat aattagagaa aatatgatta aaaatttgcc gcaaatagtg ttgttgaata
    70381 ttgtcggcct cgcgctgttt ctttcctggt atattcccat taatcatgga ttctggttgc
    70441 cgattgatgc ggatattttt tatttcttta atcagaaact ggtcgaaagt aaggcctttt
    70501 tgtggctggt tgcattgacc aacaatcgcg ctttcgacgg ttgttcactg ctggcgatgg
    70561 gaatgttgat gctgagtttc tggctgaaag aaaacgcccc aggcagacga cgtatcgtga
    70621 ttattggtct ggtcatgcta ttaactgcag tggtattaaa ccagctgggt caggcattaa
    70681 ttcctgtaaa acgggccagt ccaacgttga cttttaccaa tattaaccgc gtcagcgaac
    70741 tgctctctgt tcccacgaaa gatgcctcac gagatagctt tcccggcgat cacggtatga
    70801 tgctgcttat tttttcggca ttcatgtggc gttatttcgg caaagttgct ggccttatcg
    70861 cccttattat ttttgtggtt tttgcgtttc ccagagtaat gattggcgca cactggttta
    70921 ctgacatcat cgtcggttcc atgaccgtga tattgatcgg tttgccctgg gtgttgctga
    70981 cgccattaag tgatcgatta atcacctttt ttgacaaatc actacctgga aaaaacaaac
    71041 atttccaaaa caaataactc acagtaatta acatcatcag gtttattttt atagtgagga
    71101 taatcctgat gatgcgcctc ctgctttcat ccatcgagcg caaaaatcat tctctaagta
    71161 aatgaatgga ttgcatgcgt ttcactcaat cgtactttaa ttgaccaatc ccgctgatta
    71221 actttctgta tcactttttc ttataaaaaa tcatgtaaaa ccgctcgcca agaccgcacc
    71281 aatcgggtaa tctcgaactc gttttgcctc ggcggtagat tatcctcaca gcatataatt
    71341 ttgtgcgtta gtccacagat ttggccttaa ggaattgttt caacatgccc aggtaattag
    71401 tctcgtgtcg cttggcattt ttttataacg atatttgtcg ttaaggactt caagggaaaa
    71461 caaacaacat ggtcaaatct caaccgattt tgagatatat cttgcgcggg atccccgcga
    71521 ttgcagtagc ggttctgctt tctgcatgta gtgcaaataa caccgcaaag aatatgcatc
    71581 ctgagacacg tgcagtgggt agtgaaacat catcactgca agcttctcag gatgaatttg
    71641 aaaacctggt tcgtaatgtc gacgtaaaat cgcgaattat ggatcagtat gctgactgga
    71701 aaggcgtacg ctatcgtctg ggcggcagca ctaaaaaagg tatcgattgt tctggtttcg
    71761 tacagcgtac attccgtgag caatttggct tagaacttcc gcgttcgact tatgaacagc
    71821 aggaaatggg taaatctgtt tcccgcagta atttgcgtac gggtgattta gttctgttcc
    71881 gtgccggttc aacgggacgc catgtcggta tttatatcgg caacaaccag tttgtccatg
    71941 cttccaccag cagtggtgtt attatttcca gcatgaatga accatactgg aagaagcgtt
    72001 acaacgaagc acgccgggtt ctcagccgca gctaataaac cgtttggatg caatcccttg
    72061 gctatcctga cgagttaact gaaagcactg cttaggcagt gcttttttgt tttcattcat
    72121 cagagaaaat gatgtttccg cgtcttgatc caggctatag tccggtcatt gttatctttt
    72181 aaatgttgtc gtaatttcag gaaattaacg gaatcatgtt tatacgcgct cccaattctg
    72241 gacgtaagct cctgcttacc tgcattgttg caggcgtgat gattgcgata ctggtgagct
    72301 gccttcagtt tttagtggcc tggcataagc acgaagtcaa atacgacaca ctgattaccg
    72361 acgtacaaaa gtatctcgat acctattttg ccgaccttaa atccactact gaccggctcc
    72421 agccgctgac cttagatacc tgccagcagg ctaaccccga actgaccgcc cgcgcggcgt
    72481 ttagcatgaa tgttcgtacg tttgtgctgg taaaagataa aaaaacattc tgttcatctg
    72541 caactggtga gatggacatt ccactcaatg aattgattcc ggcgctcgac attaataaaa
    72601 acgtcgatat ggcgatctta cccggcacgc cgatggtgcc gaacaaaccc gcaatcgtca
    72661 tctggtatcg caaccctttg ctgaaaaata gcggcgtgtt tgccgctctg aatctcaacc
    72721 tgacgccttc actcttttat agttcacggc aggaagatta cgatggcctc gccctcatta
    72781 ttggtaatac tgcgctatct accttttctt cacgtttgat gaacgttaat gaattaaccg
    72841 acatgccggt ccgtgaaact aaaattgcgg gcattcctct gaccgttcgg ctttatgcag
    72901 atgactggac atggaacgat gtgtggtacg catttttact gggtggcatg agtggaactt
    72961 tcgttggact tctctgctat tacctgatga gtgtgcgtat gcgcccaggc agagaaatca
    73021 tgaccgccat caagcgcgaa caattttacg tggtatatca accggtggtt gatacacaag
    73081 ctttgcgggt aacgggcctg gaagtactgc tacgctggcg gcatcctgta gcaggagaaa
    73141 tacccccgga tgccttcatt aactttgccg aagcgcaaaa gatgattgtg ccactgactc
    73201 agcacctgtt tgagttgatt gcccgcgatg ccgcagaatt agaaaaagta ctgccggtag
    73261 gcgtcaaatt tggcattaac attgcgccgg cccacttgca cagcgaaagc tttaaagcgg
    73321 atatccagaa actgctcact tccctgcccg cacaccattt ccagattgtg ctggaaatta
    73381 ccgagcgcga tatgctgaaa gagcgagaag ccacacaact cttcgcctgg ctgcattcgg
    73441 tcggcgtaga aatcgctatt gatgacttcg gcaccgggca cagcgcgctt atctatcttg
    73501 agcgttttac gctcgattat ctgaaaattg atcgtggatt tatcaacgcc atcggtacgg
    73561 aaacgatcac ttcacccgta cttgacgcgg tgctgacgct ggcgaaacgt ctcaatatgc
    73621 tgacagttgc tgaaggggtc gaaacgccag aacaggcacg atggctaagc gaacgcggcg
    73681 ttaatttcat gcaaggctac tggattagtc gcccgttacc gctggacgat tttgttcgct
    73741 ggctgaagaa accgtatacg ccgcagtggt aaggtgtgct tacgtccctt attattcata
    73801 gtgaaagcat gccggattgc ggctaatgat gagtaaaagg aaatccgttg cagatgattg
    73861 tgcgcatact gctgctgttt atcgctctgt tcacctttgg tgcgcaggcg caggctatca
    73921 aggaaagcta tgcctttgca gtactgggcg aaccccggta cgcatttaat ttcaaccatt
    73981 ttgattatgt gaaccccgcc gcgccaaaag gtgggcaaat aacgttgtct gccctcggca
    74041 ccttcgataa tttcaaccgc tatgcactgc gcggcaatcc gggcgcacgc accgagcagc
    74101 tgtacgacac gctatttacg acttccgatg acgaaccagg cagttattac ccgctgattg
    74161 ctgaaagcgc acgctatgct gacgattatt cctgggtgga ggtcgctatt aatccacgcg
    74221 cccgttttca tgatggttcg cccattactg cccgcgatgt agagtttact tttcaaaaat
    74281 ttatgaccga aggcgtgccg caatttcgtc tggtctacaa aggcaccacc gtcaaagcca
    74341 ttgcgccgtt aaccgtgcgc attgagttag ctaaacccgg caaagaagat atgctgagtc
    74401 tgttttcgct gccggtattt ccagaaaagt actggaaaga tcacaaaatt agcgacccgc
    74461 tcgccacgcc tccgcttgcc agtggtccgt accgcattac gtcctggaaa atggggcaaa
    74521 atattgtcta ttcccgcgtg aaagattact gggcagcaaa cttaccggta aaccgtggac
    74581 gctggaattt cgacaccatt cgctacgatt attacctcga tgataatgtc gcctttgaag
    74641 cgtttaaagc aggagccttt gatttgcgta tggaaaacga cgccaaaaac tgggccacgc
    74701 gctataccgg taaaaatttc gataaaaaat acatcatcaa agatgagcaa aagaacgaat
    74761 cagcccagga tacgcgctgg ctggcgttta atatccaacg tccggtattc agcgatcgcc
    74821 gggtgcggga agcgatcact ctcgcctttg actttgaatg gatgaacaag gcgttgtttt
    74881 acaatacctg gagtcgcacg aacagttatt ttcagaatac cgaatatgcg gccagaaatt
    74941 accccgacgc cgcggaactg gtgcttctgg caccaatgaa aaaagatcta ccgccagaag
    75001 tcttcacgca aatctaccag ccgccggtat ccaaaggcga tggctacgat cgtgacaacc
    75061 tgttaaaagc cgacaaactt ctcaacgaag caggctgggt gctgaagggt cagcaacgcg
    75121 ttaatgccac aacaggtcag ccactcagct ttgaattatt gcttcccgca agcagcaata
    75181 gtcagtgggt attgccgttc cagcacagcc tgcaacggct gggtatcaac atggacattc
    75241 gcaaggtgga taactcgcaa atcaccaacc gcatgcgcag tcgcgactat gacatgatgc
    75301 cgcgcgtatg gcgggcgatg ccgtggccca gttccgattt acagatttcc tggtcatcgg
    75361 aatatatcaa ttccacttat aatgcccccg gcgtgcaaag cccggttatc gactcgctga
    75421 tcaaccaaat tattgccgcg cagggaaata aagaaaaatt actgccgttg ggacgagcac
    75481 tggatcgcgt attaacgtgg aattattaca tgctgccaat gtggtacatg gcggaagacc
    75541 gtctcgcctg gtgggataaa ttctcccaac ccgctgtacg cccagtttac agcctgggta
    75601 ttgatacctg gtggtatgac gttaataaag cgacgaaact gccgtcagcc agacaacagg
    75661 gagagtagat gggcgcttat ctgatccgcc gtctgttgct ggtgatccca acgctatggg
    75721 cgattatcac tatcaacttt ttcatcgtgc aaattgcgcc tggcggtccg gtcgaccagg
    75781 ccatcgccgc cattgagttt ggcaatgccg gagtattacc cggcgcaggc ggtgaaggtg
    75841 ttcgcgccag ccatgcgcaa acgggcgtcg gcaatatcag cgacagtaat taccgtggcg
    75901 gacgcggatt agatccagaa gtgatcgccg agatcactca tcgctacggt ttcgataagc
    75961 cgatccacga acgttacttc aaaatgctct gggactacat ccgttttgat tttggcgaca
    76021 gcctttttcg cagcgcctcg gtgctgacgc tgattaaaga cagtctgccg gtctccatca
    76081 ccctcggatt gtggagcacg ctgattatct atctggtgtc gattccgtta ggcattcgca
    76141 aagctgttta taatgggagc cgttttgacg tctggagtag tgcatttatc atcatcggct
    76201 acgccattcc ggcctttttg tttgccatcc tgctgattgt cttcttcgcg ggcggcagct
    76261 atttcgatct gttccctctg cgcggcctgg tttccgctaa ctttgattcg ctgccgtggt
    76321 atcagaaaat caccgattat ctgtggcata tcacgctgcc ggtgctggcg acagtgattg
    76381 gcggctttgc ggctctgacc atgctgacaa aaaactcatt ccttgatgaa gtgcgtaagc
    76441 aatacgtggt gacggcacgt gcgaaagggg taagtgaaaa aaatattctc tggaaacatg
    76501 tgttccgcaa cgccatgctg ctggtgattg ccggttttcc ggcgacgttt atcagcatgt
    76561 tttttaccgg ctcgctgctg attgaggtga tgttttcact caatggtctt ggcttactgg
    76621 gctacgaagc gaccgtctcg cgcgattatc ctgtaatgtt tggtaccttg tatattttca
    76681 ccctgattgg cctgctgctg aatattgtca gtgatatcag ctatacgctg gtcgatccgc
    76741 gtatagactt tgagggacgt taatgtcgcg actcagcccc gtcaatcagg cccgttgggc
    76801 gcgttttcgc cataaccgtc gcggctactg gtcgttatgg attttcctcc tcttgtttgg
    76861 tttgagtttg tgttctgaac ttatcgccaa cgataaaccg ttgctggtgc gttatgacgg
    76921 cagttggtat ttcccgttgt tgaaaaacta cagcgaaagc gattttggcg gcccgctggc
    76981 aagtcaggct gattatcagg acccgtggct gaaacaacga ctggaaaata acggctgggt
    77041 actgtgggca ccgattcgct ttggtgctac cagtatcaac tttgctaccg ataagccctt
    77101 cccttctcca ccctcccggc aaaactggct gggaacggat gccaatggcg gcgatgtgct
    77161 ggcgcgcatt ctctatggca cgcggatctc agttctgttt ggcctgatgc tgaccctctg
    77221 ctccagcgtg atgggtgtgc tggcgggggc gctacaaggc tattacggtg gtaaagtcga
    77281 tctctggggg caacgtttta ttgaagtatg gtcggggatg ccgacgctgt ttttgattat
    77341 tttactttcc agcgtcgtac agcctaactt ctggtggctg ctggcaatta ctgtcttgtt
    77401 tggctggatg agtctggtcg gcgtggtgcg ggcggagttt ttacgtaccc gtaatttcga
    77461 ctacatccgc gcggcgcagg cgcttggcgt cagcgatcgc agtatcatcc tgcgtcatat
    77521 gttgccaaat gccatggtcg ctaccctcac ttttttaccg tttattttat gtagttcgat
    77581 aaccaccctg acctcactcg atttcctcgg cttcggtctg ccgctcggtt caccgtcact
    77641 cggcgaactc ctgttacaag ggaaaaataa ccttcaggcc ccgtggcttg ggatcaccgc
    77701 cttcttatcg gtggcgatat tgttgtcttt gctgatcttt attggtgaag ccgtccgcga
    77761 cgcatttgat cctaataagg cggtgtagca tgacgcaaac tctgttagcg attgaaaatt
    77821 tgtcggtggg ttttcgccat cagcaaactg ttcgtaccgt agtgaatgat gtgtcactac
    77881 acattgaggc tggcgaaacg ctggcgctgg taggtgagtc tggttcaggt aagagcgtta
    77941 ccgcgctgtc aattttacgc ctgctccctt gcccgccggt tgaatatctc tccggcgata
    78001 ttcgttttca tggcgaatcg ctgcttcatg ccagcgatca aacgttgcgc ggtgtacgcg
    78061 gtaataagat cgccatgatt tttcaggagc cgatggtgtc gttaaatcca ttacataccc
    78121 tggaaaaaca gctttatgaa gtgctttcac tccaccgcgg gatgcgtcgg gaagcggctc
    78181 gtggcgaaat tcttaactgc cttgatcgcg tcggtatccg ccaggcggca aaacggctga
    78241 cagattatcc gcatcagctc tccggcggcg aacgccagcg ggtgatgatt gcgatggcgc
    78301 tgttaacgcg accggaatta ttaattgccg atgaaccaac caccgcgctg gacgtctctg
    78361 tccaggcgca gattttacag ctgttgcgcg aactgcaagg cgagctgaat atgggtatgc
    78421 tgtttattac tcataacctc agcattgtta gaaaactggc ccaccgcgtg gcggtaatgc
    78481 aaaacggtcg ctgtgtcgag aaaaataacg ccgctacgct atttgcctca cccactcatc
    78541 cttacacaca aaagctactc aacagtgaac catctggcga cccggtgcca ttgccagaac
    78601 ctgcctcaac gttgctggat gttgaacaac ttcaggttgc cttccccatt cgcaaaggga
    78661 ttttgaagcg cattgtggat cataatgtgg tggtgaaaaa catcagtttt acgctacggg
    78721 cgggtgaaac actgggttta gtgggcgagt ccggttccgg gaaaagcacg acgggactgg
    78781 cgctgctgcg actgattaac tctcatggca gcatcgtctt tgacggtcag ccactgcaaa
    78841 atttaaatcg ccgccagctg ttacctattc gtcatcgcat tcaggtggta tttcaggatc
    78901 caaactcctc actcaaccca cgactcaacg ttttgcaaat tattgaggaa ggcttacggg
    78961 ttcaccagcc gacgctttct gccgcacaac gcgaacaaca agtgatagcc gtgatgcatg
    79021 aagtgggatt agatcctgaa acacgccacc gttatccggc ggagttctct ggtggtcagc
    79081 ggcaacgtat tgcgattgcc agggcgttaa ttcttaagcc ctcgctgatc attcttgatg
    79141 aaccaacatc atcactcgac aaaacggtgc aggcgcaaat attgacgcta ttgaaatcat
    79201 tgcaacaaaa gcatcaactg gcctatttgt ttatcagcca cgatttgcac gttgtccgcg
    79261 cgttatgtca tcaggttatc gtactgcgac aaggggaagt agtggaacaa ggaccgtgcg
    79321 cgcgcgtgtt tgccgcaccg cagcaggagt atacgcgtca gctactggcg ttgagctgac
    79381 gcttaaaaag gattgtagtt tgaaaagggt tcggcaattg ccacaccaaa atttttcaat
    79441 cggcatgttg cagcaaattc gtcctggcga tttacaaaca ggcacggctc accttcacac
    79501 tccagcaccg aacatggaac ttcgatgtcg cttaacgcct ggcttagttt gtacatcacc
    79561 gaccatgcat tatcaccatc cgggctaagc aatttaagcg ccaccaggct gttgtcaccg
    79621 cacggtccat tttgcggaat cggttcaacc ttcgaacctg cgaaaccagc agaccagcga
    79681 tagttctgcg gcagtcgatg gacgattgag agttgtaatg aagtcactta ttttccccgg
    79741 aagtacattt tacttcacaa tttatttaca tcaattttaa cacatcatca acaatccgtc
    79801 tttatacaga tcgtaaagat tgatgcctcg cctgcgtggc ctatatggct ctgatttaaa
    79861 taatatctgc gggcgtggtc acgtttgcgg ggctatatgt acccgtttct gcgatctaac
    79921 tcaacctttt ta
//
LOCUS       DAFGPF010000007        76408 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFGPF010000007 DAFGPF010000000
VERSION     DAFGPF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 76408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76408
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.007"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            133..636
                     /gene="dps"
                     /locus_tag="LSX49_000596"
                     /gene_synonym="pexB"
     CDS             133..636
                     /gene="dps"
                     /locus_tag="LSX49_000596"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HBL7167055.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
     gene            1040..1786
                     /gene="glnH"
                     /locus_tag="LSX49_000597"
     CDS             1040..1786
                     /gene="glnH"
                     /locus_tag="LSX49_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HBL7167056.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            1925..2584
                     /gene="glnP"
                     /locus_tag="LSX49_000598"
     CDS             1925..2584
                     /gene="glnP"
                     /locus_tag="LSX49_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HBL7167057.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            2581..3303
                     /gene="glnQ"
                     /locus_tag="LSX49_000599"
     CDS             2581..3303
                     /gene="glnQ"
                     /locus_tag="LSX49_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HBL7167058.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     DPQVLIKNPPSQRLQEFLQHVS"
     gene            3420..5645
                     /gene="ybiO"
                     /locus_tag="LSX49_000600"
     CDS             3420..5645
                     /gene="ybiO"
                     /locus_tag="LSX49_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HBL7167059.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYCKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKTVLRLIFCPNVAELRPFTIHDETARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLVIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGAAPAEPLPPGEPT
                     L"
     gene            complement(5642..6568)
                     /gene="rlmF"
                     /locus_tag="LSX49_000601"
     CDS             complement(5642..6568)
                     /gene="rlmF"
                     /locus_tag="LSX49_000601"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HBL7167060.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            6844..7104
                     /locus_tag="LSX49_000602"
     CDS             6844..7104
                     /locus_tag="LSX49_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBL7167061.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTAIIYK"
     gene            7369..9651
                     /locus_tag="LSX49_000603"
     CDS             7369..9651
                     /locus_tag="LSX49_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
                     /protein_id="HBL7167062.1"
                     /translation="MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQANADDTL
                     VVEASTPSLYAPQKSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVG
                     AFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
                     YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGE
                     KTHDAGRDKVKNERYGVAPSVAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGFSA
                     PSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVK
                     QDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGAIGH
                     DVSTGVEFTRETQTNYGVNPVTLPTVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYA
                     FDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPAGVAKGSPVTTVDTAK
                     SGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKA
                     NTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNI
                     TPAWQMIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGAR
                     YIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKS
                     GYRYHPGEPRTFLLTANMHF"
     gene            9693..10370
                     /gene="ybiX"
                     /locus_tag="LSX49_000604"
     CDS             9693..10370
                     /gene="ybiX"
                     /locus_tag="LSX49_000604"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HBL7167063.1"
                     /translation="MMYHIPGVLSPQDVARFREHLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSALYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPESYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSHYGESEEILSLLNLYHNL
                     LREWSEI"
     gene            10444..10710
                     /gene="ybiI"
                     /locus_tag="LSX49_000605"
     CDS             10444..10710
                     /gene="ybiI"
                     /locus_tag="LSX49_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HBL7167064.1"
                     /translation="MASGWANDDAVNEQINSTIEDAIARARGEIPRGESLYECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            10975..11235
                     /locus_tag="LSX49_000606"
     CDS             10975..11235
                     /locus_tag="LSX49_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBL7167065.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(11373..12458)
                     /gene="hcxB"
                     /locus_tag="LSX49_000607"
     CDS             complement(11373..12458)
                     /gene="hcxB"
                     /locus_tag="LSX49_000607"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcXB"
                     /protein_id="HBL7167066.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKVVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCSAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGS
                     WQAICDAARQIGMPEETLQAFCQQLAS"
     gene            complement(12598..13560)
                     /gene="ybiB"
                     /locus_tag="LSX49_000608"
     CDS             complement(12598..13560)
                     /gene="ybiB"
                     /locus_tag="LSX49_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HBL7167067.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDTAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLMATGEAATISDGLARVNQAF"
     gene            complement(13588..15738)
                     /gene="dinG"
                     /locus_tag="LSX49_000609"
     CDS             complement(13588..15738)
                     /gene="dinG"
                     /locus_tag="LSX49_000609"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HBL7167068.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSIDNEEQHIAEMAAFFREQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGALLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            15842..16042
                     /locus_tag="LSX49_000610"
                     /pseudo
     CDS             15842..16042
                     /locus_tag="LSX49_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1768 domain-containing protein"
     gene            complement(16275..17636)
                     /gene="rhlE"
                     /locus_tag="LSX49_000611"
     CDS             complement(16275..17636)
                     /gene="rhlE"
                     /locus_tag="LSX49_000611"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HBL7167069.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAILGYEPDPSIKAEPIQNGRQ
                     QRGGGRGQGGGRGQQQPRRAESGAKSGNAKPAEKPSRRLGDAKPAGEQQRRRRPRKPA
                     AAQ"
     gene            17865..18536
                     /gene="cecR"
                     /locus_tag="LSX49_000612"
     CDS             17865..18536
                     /gene="cecR"
                     /locus_tag="LSX49_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HBL7167070.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     SDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            18539..19534
                     /gene="hlyD"
                     /locus_tag="LSX49_000613"
     CDS             18539..19534
                     /gene="hlyD"
                     /locus_tag="LSX49_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HBL7167071.1"
                     /translation="MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTV
                     NLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRA
                     VEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE"
     gene            19527..21263
                     /locus_tag="LSX49_000614"
     CDS             19527..21263
                     /locus_tag="LSX49_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415315.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7167072.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGSATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPTALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKETTPD
                     DIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHSNE"
     gene            21256..22389
                     /locus_tag="LSX49_000615"
     CDS             21256..22389
                     /locus_tag="LSX49_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7167073.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANAIAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLIVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            22400..23506
                     /locus_tag="LSX49_000616"
     CDS             22400..23506
                     /locus_tag="LSX49_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7167074.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(23468..23878)
                     /locus_tag="LSX49_000617"
     CDS             complement(23468..23878)
                     /locus_tag="LSX49_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HBL7167075.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            24011..24772
                     /locus_tag="LSX49_000618"
     CDS             24011..24772
                     /locus_tag="LSX49_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL7167076.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGESVLVAGDFNDWRQKANHPLKVLAGLDEIFTRAHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            24769..26010
                     /gene="clsB"
                     /locus_tag="LSX49_000619"
     CDS             24769..26010
                     /gene="clsB"
                     /locus_tag="LSX49_000619"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HBL7167077.1"
                     /translation="MKCSWREGNMIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSTARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRNFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            26010..26966
                     /locus_tag="LSX49_000620"
     CDS             26010..26966
                     /locus_tag="LSX49_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HBL7167078.1"
                     /translation="MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGVIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVSYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGT
                     IIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM"
     gene            complement(27002..27715)
                     /locus_tag="LSX49_000621"
     CDS             complement(27002..27715)
                     /locus_tag="LSX49_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL7167079.1"
                     /translation="MESYSQNSNKLDFQHEARILNGIWLITALGLVATAGLAWGAKYL
                     EITATKYDSPQMYVAIGLLLLSMYGLSKDINKINTAIAGVIYLFLISLVAIVVASLAP
                     VSAIIVVFSTAGSMFLISMLAGLLFKFDPGSHRFIIMMTLTGLALVIIVNATLMSERP
                     IWVISCLMIVLWSGIISHGRNKLLELTGKSHSEELWSPVRCAFIGALTLYYYFIGFFG
                     ILAAIAITLVWQRHTRFFH"
     gene            complement(27921..28625)
                     /locus_tag="LSX49_000622"
     CDS             complement(27921..28625)
                     /locus_tag="LSX49_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL7167080.1"
                     /translation="MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            complement(28762..29214)
                     /gene="moaE"
                     /locus_tag="LSX49_000623"
     CDS             complement(28762..29214)
                     /gene="moaE"
                     /locus_tag="LSX49_000623"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HBL7167081.1"
                     /translation="MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVKALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            complement(29216..29461)
                     /gene="moaD"
                     /locus_tag="LSX49_000624"
     CDS             complement(29216..29461)
                     /gene="moaD"
                     /locus_tag="LSX49_000624"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HBL7167082.1"
                     /translation="MINVLFFAQVRELVGTDATEVAADFPTVEALRQHLAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHSLTDGDEVAFFPPVTGG"
     gene            complement(29454..29939)
                     /gene="moaC"
                     /locus_tag="LSX49_000625"
     CDS             complement(29454..29939)
                     /gene="moaC"
                     /locus_tag="LSX49_000625"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBL7167083.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            complement(29942..30454)
                     /gene="moaB"
                     /locus_tag="LSX49_000626"
     CDS             complement(29942..30454)
                     /gene="moaB"
                     /locus_tag="LSX49_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HBL7167084.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            complement(30476..31465)
                     /gene="moaA"
                     /locus_tag="LSX49_000627"
     CDS             complement(30476..31465)
                     /gene="moaA"
                     /locus_tag="LSX49_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBL7167085.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLENDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     regulatory      complement(31453..31597)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            31862..32770
                     /gene="yvcK"
                     /locus_tag="LSX49_000628"
     CDS             31862..32770
                     /gene="yvcK"
                     /locus_tag="LSX49_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HBL7167086.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDAHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTAP
                     IQELLLTPNVPATREAVHAISEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVL
                     EASDIPYRHDRQLLHSALEKALQALG"
     gene            complement(32808..34829)
                     /gene="uvrB"
                     /locus_tag="LSX49_000629"
     CDS             complement(32808..34829)
                     /gene="uvrB"
                     /locus_tag="LSX49_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HBL7167087.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(35408..36085)
                     /gene="bioD"
                     /locus_tag="LSX49_000630"
     CDS             complement(35408..36085)
                     /gene="bioD"
                     /locus_tag="LSX49_000630"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HBL7167088.1"
                     /translation="MSKCYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGS
                     EKTPKGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIEALVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QAILHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLALM"
     gene            complement(36078..36833)
                     /gene="bioC"
                     /locus_tag="LSX49_000631"
     CDS             complement(36078..36833)
                     /gene="bioC"
                     /locus_tag="LSX49_000631"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HBL7167089.1"
                     /translation="MATVNKQAIAAAFGRAAAHYEQHADLQRQSADTLLAMLPQRKYT
                     RVLDAGCGPGWMSRRWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRFLPPDEIEQSLNAVHYQHYIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE"
     gene            complement(36820..37974)
                     /gene="bioF"
                     /locus_tag="LSX49_000632"
     CDS             complement(36820..37974)
                     /gene="bioF"
                     /locus_tag="LSX49_000632"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HBL7167090.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVVDDRQYLNF
                     SSNDYLGLSHHPQIIRAWKQGAEQFGIGSGGSGHVSGYSVAHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSPLRRFAHNDVTHLAR
                     LLASPCPGQQLVVTEGVFSMDGDSAPLEEIQQVTQQHDGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSNTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSWSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG"
     gene            complement(37971..39011)
                     /gene="bioB"
                     /locus_tag="LSX49_000633"
     CDS             complement(37971..39011)
                     /gene="bioB"
                     /locus_tag="LSX49_000633"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBL7167091.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            39098..40387
                     /gene="bioA"
                     /locus_tag="LSX49_000634"
     CDS             39098..40387
                     /gene="bioA"
                     /locus_tag="LSX49_000634"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HBL7167092.1"
                     /translation="MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHNLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQH
                     QVAAIEAQLREQLAPACDAEMVADVRVLGAIGVVETSRPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ"
     gene            40446..40922
                     /locus_tag="LSX49_000635"
     CDS             40446..40922
                     /locus_tag="LSX49_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HBL7167093.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPVGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDVERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            41074..42357
                     /locus_tag="LSX49_000636"
     CDS             41074..42357
                     /locus_tag="LSX49_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HBL7167094.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDKVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     ASGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVD
                     DNDEVQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(42498..44759)
                     /locus_tag="LSX49_000637"
     CDS             complement(42498..44759)
                     /locus_tag="LSX49_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HBL7167095.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVAALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSEMAEVFARIKQIAGQEHVDPL
                     QTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEAPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(44942..46375)
                     /locus_tag="LSX49_000638"
     CDS             complement(44942..46375)
                     /locus_tag="LSX49_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HBL7167096.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSGGEFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGSTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            complement(46451..47503)
                     /locus_tag="LSX49_000639"
     CDS             complement(46451..47503)
                     /locus_tag="LSX49_000639"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HBL7167097.1"
                     /translation="MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGND
                     LEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGA
                     FAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
                     LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELD
                     ADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRA
                     LAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRAS
                     VIRTTRKIFSGEVYLP"
     gene            47687..48640
                     /locus_tag="LSX49_000640"
     CDS             47687..48640
                     /locus_tag="LSX49_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308823.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7167098.1"
                     /translation="MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEED
                     LHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFSIRDMNAYHRGMVTLACIPT
                     AVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
                     PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLD
                     WFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKD
                     AVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG"
     gene            complement(48681..49676)
                     /gene="pgl"
                     /locus_tag="LSX49_000641"
     CDS             complement(48681..49676)
                     /gene="pgl"
                     /locus_tag="LSX49_000641"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HBL7167099.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            49831..50649
                     /gene="ybhA"
                     /locus_tag="LSX49_000642"
     CDS             49831..50649
                     /gene="ybhA"
                     /locus_tag="LSX49_000642"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyridoxal
                     phosphate/fructose-1,6-bisphosphate phosphatase"
                     /protein_id="HBL7167100.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            complement(50650..51708)
                     /gene="modC"
                     /locus_tag="LSX49_000643"
     CDS             complement(50650..51708)
                     /gene="modC"
                     /locus_tag="LSX49_000643"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HBL7167101.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDADKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMA
                     KSMVNQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGCKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(51711..52400)
                     /gene="modB"
                     /locus_tag="LSX49_000644"
     CDS             complement(51711..52400)
                     /gene="modB"
                     /locus_tag="LSX49_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBL7167102.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGLSFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            complement(52400..53173)
                     /gene="modA"
                     /locus_tag="LSX49_000645"
     CDS             complement(52400..53173)
                     /gene="modA"
                     /locus_tag="LSX49_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7167103.1"
                     /translation="MARKWLNLFTGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTASRQ
                     TLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK"
     gene            complement(53340..53489)
                     /gene="acrZ"
                     /locus_tag="LSX49_000646"
     CDS             complement(53340..53489)
                     /gene="acrZ"
                     /locus_tag="LSX49_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump accessory protein AcrZ"
                     /protein_id="HBL7167104.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            53618..54406
                     /gene="modE"
                     /locus_tag="LSX49_000647"
     CDS             53618..54406
                     /gene="modE"
                     /locus_tag="LSX49_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HBL7167105.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            54474..55946
                     /gene="modF"
                     /locus_tag="LSX49_000648"
     CDS             54474..55946
                     /gene="modF"
                     /locus_tag="LSX49_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HBL7167106.1"
                     /translation="MSSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSA
                     LARALSGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTT
                     AEIIQDEVKDTSRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQHLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSELLEGVQMPEPDEPSARHALPANEPRIVLNNGVVSYNERPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGGLYRYVLTKIN"
     gene            56209..57225
                     /gene="galE"
                     /locus_tag="LSX49_000649"
     CDS             56209..57225
                     /gene="galE"
                     /locus_tag="LSX49_000649"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308814.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBL7167107.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGSSVLDVVNAF
                     SKACGKPVNYHFAPRRAGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            57235..58281
                     /gene="galT"
                     /locus_tag="LSX49_000650"
     CDS             57235..58281
                     /gene="galT"
                     /locus_tag="LSX49_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBL7167108.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESNDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQIWANSFLPNEAEREDRLQKEYFAGQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            58285..59433
                     /gene="galK"
                     /locus_tag="LSX49_000651"
     CDS             58285..59433
                     /gene="galK"
                     /locus_tag="LSX49_000651"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBL7167109.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            59427..60467
                     /gene="galM"
                     /locus_tag="LSX49_000652"
     CDS             59427..60467
                     /gene="galM"
                     /locus_tag="LSX49_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HBL7167110.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDVRNHKLQILAEEYLPVDEGGIPHDGLKSVAGT
                     SFDFRNAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAQ"
     gene            60670..61422
                     /gene="gpmA"
                     /locus_tag="LSX49_000653"
     CDS             60670..61422
                     /gene="gpmA"
                     /locus_tag="LSX49_000653"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL7167111.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(61589..62641)
                     /gene="aroG"
                     /locus_tag="LSX49_000654"
     CDS             complement(61589..62641)
                     /gene="aroG"
                     /locus_tag="LSX49_000654"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HBL7167112.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWDDT
                     DALLRQLANAVKARRG"
     gene            62957..63337
                     /locus_tag="LSX49_000655"
     CDS             62957..63337
                     /locus_tag="LSX49_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HBL7167113.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHPDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            63451..64392
                     /gene="zitB"
                     /locus_tag="LSX49_000656"
     CDS             63451..64392
                     /gene="zitB"
                     /locus_tag="LSX49_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HBL7167114.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVIGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRLCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNRGVSGHSHHHH"
     gene            complement(64389..65108)
                     /gene="pnuC"
                     /locus_tag="LSX49_000657"
     CDS             complement(64389..65108)
                     /gene="pnuC"
                     /locus_tag="LSX49_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HBL7167115.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVAMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWIKSARERGSRALSH"
     gene            complement(65146..66189)
                     /gene="nadA"
                     /locus_tag="LSX49_000658"
     CDS             complement(65146..66189)
                     /gene="nadA"
                     /locus_tag="LSX49_000658"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBL7167116.1"
                     /translation="MSVMFDPDTAIYPFPPKPTPLSIDEKANYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVEMADAVGSTSQLIAAAKTLQHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHEVYVDERLRERALVP
                     LNRMLDFAATLRG"
     gene            complement(66467..66542)
                     /locus_tag="LSX49_000659"
     tRNA            complement(66467..66542)
                     /locus_tag="LSX49_000659"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(66507..66509),aa:Lys,seq:ttt)
     gene            complement(66576..66651)
                     /locus_tag="LSX49_000660"
     tRNA            complement(66576..66651)
                     /locus_tag="LSX49_000660"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(66616..66618),aa:Lys,seq:ttt)
     gene            complement(66700..66775)
                     /locus_tag="LSX49_000661"
     tRNA            complement(66700..66775)
                     /locus_tag="LSX49_000661"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(66740..66742),aa:Lys,seq:ttt)
     gene            complement(66779..66854)
                     /locus_tag="LSX49_000662"
     tRNA            complement(66779..66854)
                     /locus_tag="LSX49_000662"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(66819..66821),aa:Val,seq:tac)
     gene            complement(66906..66981)
                     /locus_tag="LSX49_000663"
     tRNA            complement(66906..66981)
                     /locus_tag="LSX49_000663"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(66946..66948),aa:Lys,seq:ttt)
     gene            complement(66984..67059)
                     /locus_tag="LSX49_000664"
     tRNA            complement(66984..67059)
                     /locus_tag="LSX49_000664"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67024..67026),aa:Val,seq:tac)
     gene            complement(67095..67170)
                     /locus_tag="LSX49_000665"
     tRNA            complement(67095..67170)
                     /locus_tag="LSX49_000665"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67135..67137),aa:Lys,seq:ttt)
     gene            complement(67335..68126)
                     /gene="cpoB"
                     /locus_tag="LSX49_000666"
     CDS             complement(67335..68126)
                     /gene="cpoB"
                     /locus_tag="LSX49_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HBL7167117.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSGDQSGVVASTTPTADAGTSNAGAPVKSGDANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            complement(68136..68657)
                     /gene="pal"
                     /locus_tag="LSX49_000667"
     CDS             complement(68136..68657)
                     /gene="pal"
                     /locus_tag="LSX49_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HBL7167118.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYAKNRRAVLVY"
     gene            complement(68692..69984)
                     /gene="tolB"
                     /locus_tag="LSX49_000668"
     CDS             complement(68692..69984)
                     /gene="tolB"
                     /locus_tag="LSX49_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HBL7167119.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            complement(70117..71427)
                     /gene="tolA"
                     /locus_tag="LSX49_000669"
     CDS             complement(70117..71427)
                     /gene="tolA"
                     /locus_tag="LSX49_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HBL7167120.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAVEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAAD
                     KKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNA
                     SPAGSGNTKNNGASGADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLD
                     IKPEGGDPALCQAALAAAKLAKIPKPPSQAVYEVFKNAPLDFKP"
     gene            complement(71492..71920)
                     /gene="tolR"
                     /locus_tag="LSX49_000670"
     CDS             complement(71492..71920)
                     /gene="tolR"
                     /locus_tag="LSX49_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HBL7167121.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            complement(71924..72616)
                     /gene="tolQ"
                     /locus_tag="LSX49_000671"
     CDS             complement(71924..72616)
                     /gene="tolQ"
                     /locus_tag="LSX49_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HBL7167122.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLSGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            complement(72613..73017)
                     /gene="ybgC"
                     /locus_tag="LSX49_000672"
     CDS             complement(72613..73017)
                     /gene="ybgC"
                     /locus_tag="LSX49_000672"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HBL7167123.1"
                     /translation="MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENT
                     LLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ"
     gene            complement(73167..73460)
                     /gene="ybgE"
                     /locus_tag="LSX49_000673"
     CDS             complement(73167..73460)
                     /gene="ybgE"
                     /locus_tag="LSX49_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HBL7167124.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGFFCPLLADIVLIVGLIFFFF"
     gene            complement(73460..73573)
                     /gene="cydX"
                     /locus_tag="LSX49_000674"
     CDS             complement(73460..73573)
                     /gene="cydX"
                     /locus_tag="LSX49_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HBL7167125.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            complement(73588..74727)
                     /gene="cydB"
                     /locus_tag="LSX49_000675"
     CDS             complement(73588..74727)
                     /gene="cydB"
                     /locus_tag="LSX49_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HBL7167126.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            complement(74743..76311)
                     /gene="cydA"
                     /locus_tag="LSX49_000676"
     CDS             complement(74743..76311)
                     /gene="cydA"
                     /locus_tag="LSX49_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415261.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HBL7167127.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
BASE COUNT        18489 a        20366 c        19288 g        18265 t
ORIGIN      
        1 ttattgtttt tgtttttcac gcttgttacc actattagtg tgataggaac agccagaata
       61 gcggaacaca tagctggtgc tatacttagt ctcgttaatt actgggacat aacatcaaga
      121 ggatatgaaa ttatgagtac cgctaaatta gttaaatcaa aagcgaccaa tctgctttat
      181 acccgcaacg atgtctctga cagcgagaaa aaagcaacag tagagttgct gaatcgccag
      241 gttatccagt ttattgatct ttctttgatt accaaacaag cgcactggaa catgcgcggc
      301 gctaacttca ttgccgtaca tgaaatgctg gatggcttcc gcactgcact gatcgatcat
      361 ctggatacca tggcagaacg tgcagtgcag ctgggcggtg tagctctggg gaccactcaa
      421 gttatcaaca gcaaaactcc gctgaaaagt tacccgctgg acatccacaa cgttcaggat
      481 cacctgaaag agctggctga ccgttacgca atcgtcgcta atgacgtacg caaagcgatt
      541 ggcgaagcga aagatgacga caccgcagat atcctgaccg ccgcgtctcg cgacctggat
      601 aaattcctgt ggtttatcga gtctaacatc gaataaatcc atcgctgatg gtgcagaact
      661 ttagtacacg ataaaagcgg cttcctgaca ggaggccgtt ttgttttgta gcccgcctca
      721 acgcacttat ttagtgcatc catctgctat ccccagctgg ttaagtaaat tttttgtatc
      781 cacatcatca cacaatcgtt acataaagat tgttttttca tcaggtttta cgctaaataa
      841 tcactgtgtt gagtgcacaa ttttagcgca ccagtttggt gccccagaat ggtgcatctt
      901 cagggtattg ccctataaat cgtgcatcac gtttttgccg catctcgaaa aatcaatgag
      961 ttgcaaaact ggcacgattt tttcatatat gtgaatgtca cgcaggggat cgtcccgtgg
     1021 atagaaaaaa ggaaatgcta tgaagtctgt attaaaagtt tcactggctg cactgaccct
     1081 ggcttttgcg gtttcttctc atgccgcgga taaaaaatta gttgtcgcga cggataccgc
     1141 cttcgttccg tttgaattta aacagggcga taaatacgtg ggctttgacg ttgatctgtg
     1201 ggctgccatc gctaaagaac tgaagctgga ttacgaactg aagccgatgg atttcagtgg
     1261 gatcattccg gcactgcaaa ccaaaaacgt cgatctggcg ctggcgggca ttaccatcac
     1321 cgacgagcgt aaaaaagcga tcgatttctc tgacggctac tacaaaagcg gcctgttagt
     1381 gatggtgaaa gctaacaata acgatgtgaa aagcgtgaaa gatctcgacg ggaaagtggt
     1441 tgctgtgaag agcggcactg gctccgttga ttacgcgaaa gcaaacatca aaactaaaga
     1501 tctgcgtcag ttcccgaaca tcgataacgc ctatatggaa ctgggcacca accgcgcaga
     1561 cgccgttctg cacgatacgc caaacattct gtacttcatc aaaaccgccg gtaacggtca
     1621 gttcaaagcg gtaggtgact ctctggaagc acagcaatac ggtattgcgt tcccgaaagg
     1681 tagcgacgag ctgcgtgaca aagtcaacgg cgcgttgaaa accctgcgcg agaacggaac
     1741 ttacaacgaa atctacaaaa aatggttcgg tactgaaccg aaataataac gctgcgcctg
     1801 taaagcgcac tggcagttcc ctctccccgc cggggagagg attagggtga agggcgcaaa
     1861 cccgctccgg ggccattaat taccctgaat ttgattattt acaccacggt aacaggaaca
     1921 acatatgcag tttgactgga gtgccatctg gcctgccatt ccgcttctga ttgaaggtgc
     1981 caaaatgacc ctgtggattt cggtcctcgg tctggctggc ggtctggtga tcggattgtt
     2041 ggcaggtttt gcacgcacct tcggtggttg gatagccaac cacgtcgcgc tggtctttat
     2101 tgaagtgatc cgcggcacac ctatcgtcgt ccaggtgatg tttatctatt tcgccctgcc
     2161 gatggcgttt aacgatttac gcatcgaccc gtttactgcg gcggtggtca ccatcatgat
     2221 caactccggc gcgtacattg cggaaatcac gcgtggtgcg gtgctgtcta ttcacaaagg
     2281 ttttcgtgaa gcaggactgg cgctcggtct ttcacgttgg gaaaccattc gctacgtcat
     2341 tttaccgctg gcactgcgtc gtatgctgcc gccgctgggt aaccagtgga tcatcagcat
     2401 taaagacact tcgctgttta ttgttatcgg cgtggcggaa ctgacccgtc aggggcaaga
     2461 aattattgcc ggtaacttcc gcgcccttga gatctggagc gccgtggcgg tgttctatct
     2521 gattattacc ctggtgctga gctttattct gcgtcgtctg gaaagaagga tgaaaatcct
     2581 gtgattgaat ttaaaaacgt ctccaagcat tttggtccaa cccaggtgct gcacaatatc
     2641 gatttgaaca ttgctcaggg cgaagtcgtg gtgattatcg ggccgtccgg ttccggtaaa
     2701 tcgaccctgc tgcgctgcat caacaaactg gaagaaatca cctccggcga tctgattgtc
     2761 gatggcctga aggttaacga tccgaaagtt gatgagcgcc tgattcgcca ggaagcgggt
     2821 atggtgttcc agcagtttta cctcttcccg catctgacgg cgctggaaaa cgtcatgttt
     2881 ggcccgctac gcgtgcgtgg cgcgaataaa gaagaggcgg aaaaactggc gcgtgagctg
     2941 ctggcgaaag tcggtctggc agagcgtgca catcactacc cttccgaact ttctggtggt
     3001 caacagcagc gtgtggcgat tgcccgcgcg ctggcggtga agccgaaaat gatgctgttt
     3061 gatgaaccga cttccgctct tgacccggaa ctgcgccatg aagtgctgaa ggttatgcag
     3121 gatctggctg aagaagggat gacgatggtg atcgtgaccc acgaaatcgg ttttgccgag
     3181 aaagtagctt cgcgcctgat ctttatcgac aaaggccgga ttgcagaaga tggcgatccg
     3241 caggtgttga tcaagaaccc gccgagccag cgcttgcagg aatttttgca gcacgtctct
     3301 taacttctct gcctcccttt cccccgaaag ggaggcacac cagattcctc tcatttaaaa
     3361 ttgcctctcc cccagcatct atacttatct ttttgctctg ttttctcact ggaggagtca
     3421 tgcggtggat cctgttcatc ctcttctgcc tgctgggcgc acctgcccac gcggtatcca
     3481 tacccggcgt tacaaccaca acgacaacgg actcaacgac tgaaccggcc ccggaaccgg
     3541 atatcgaaca aaaaaaagcg gcctatggcg cactggcgga tgtgctggat aatgacacct
     3601 cgcgtaaaga gttgatcgac cagttgcgca ccgtcgccgc gacgccccct gcggaaccgg
     3661 taccgaagat cgtgccgccg acgctggttg aagagcaaac cgtgctgcaa aaggtcaccg
     3721 aagtcagccg ccattatggt gaagcccttt ccgcccgctt cgggcaactt tatcgcaata
     3781 tcaccggctc cccgcataag ccgtttaatc cacaaacctt cagcaatgcg ctgacccact
     3841 tttcaatgtt agcggtatta gtgtttggtt tttactggct gattcgtctg tgcgcactgc
     3901 cgctgtattg caaaatgggc cagtgggcgc ggcaaaaaaa tcgtgagcgc agtaactggt
     3961 tgcagcttcc ggcgatgatc atcggggcgt ttattatcga cctgctgtta ctggcactga
     4021 cattatttgt cggccaggta ttaagcgaca acctgaatgc gggcagtcgc accatcgctt
     4081 tccaacaaag tttgtttctc aacgcctttg ccctgattga atttttcaaa accgtactac
     4141 gcctgatttt ttgcccaaac gtagctgaac tgcgcccgtt cacgattcat gacgagaccg
     4201 cccgttactg gagtcgtcgc ctgagctggt taagcagcct gattggctat ggtctgattg
     4261 tggctgtgcc gattatctct aatcaggtga atgtacagat aggtgcgctg gcgaacgtca
     4321 tcattatgct gtgcatgacc gtctgggcgt tgtacctgat ttttcgtaat aaaaaagaga
     4381 tcacccagca tttgctcaac tttgcggagc attcgctggc ctttttcagc ctgtttatcc
     4441 gcgcctttgc actggtgtgg cactggctgg caagcgccta ttttatcgtg ctgtttttct
     4501 tttcgttgtt cgatccgggc aacagcctga aatttatgat gggtgcaacg gtgcgcagcc
     4561 tggcgattat tggtatcgca gcatttgttt ccggtatgtt ttcccgctgg ctggcgaaaa
     4621 ccatcaccct ctcgccacat actcagcgaa attatccgga gctgcaaaaa cggctgaatg
     4681 gatggctttc ggcggcactg aaaacagcgc gtattctgac agtctgcgtg gcggtaatgc
     4741 tgctgttgag cgcatgggga ttgttcgatt tctggaactg gctgcaaaac ggtgcggggc
     4801 agaaaaccgt agatatcctg atccgtatcg cactcattct tttcttctcg gcggttggct
     4861 ggacggtgct cgccagtttg atagaaaacc ggctggcttc ggatattcat ggccgcccgc
     4921 tacccagcgc ccgtacgcgt accctgctaa cgctgttccg taacgcgctg gcggtgatta
     4981 tcagtaccat caccatcatg attgtgttgt cggaaatcgg cgtcaatatc gcgccattgc
     5041 tggcaggtgc cggtgcattg ggactggcta tctcttttgg ttcgcaaacg ctggtgaaag
     5101 atattatcac cggggtattt attcagtttg aaaacggcat gaacactgga gatttggtga
     5161 ctatcgggcc gttgaccggc actgtggaac ggatgtcaat tcgctccgtg ggcgtgcgcc
     5221 aggataccgg ggcgtatcac atcattccgt ggtcttcgat aaccaccttt gctaacttcg
     5281 tccgcggtat tggttcggta gtggcaaact acgatgttga tcgccatgaa gatgctgata
     5341 aagccaatca ggcactgaaa gatgcggtag cagaattgat ggaaaacgaa gaaattcgcg
     5401 ggctggttat tggtgaaccg aattttgccg ggattgtcgg cttaagcaat accgcgttta
     5461 cactgcgtgt ttcgttcacc acgctgccac tcaaacagtg gacggtacgc tttgccctcg
     5521 acagccaggt gaaaaaacat ttcgacctgg cgggtgttcg cgcgccggtg cagacttatc
     5581 aggtgctgcc agctccgggc gcggccccgg ctgaaccgtt gccgccgggg gagccaacgc
     5641 tttaacgctg gcgattgaca aaacggcggc gctgctcgtc gttcataaag gtccaggcta
     5701 taaagcggct ctgcttttgc ccctgggcca tctctttttt taccaccttc accgcaccta
     5761 cgtccgtcaa agcacgatac aacggcggta agttttcacc acgagatacc agcgaggtaa
     5821 accacatcac ctgcttcgcg aagcctttgc tctcttcaat catctttttg ataaaagcga
     5881 cctcaccgcc ttcacaccac aactcctgtt gctgaccacc aaagttcagt gcatcgtctt
     5941 tgttcagccc caggttacgg cgtttacgtt cactacctgc ccgtgccgca gcggcggaat
     6001 cgtggaatgg cgggttacac aaggtcgcat cgtattgctc gtttttatgg atgatgccgt
     6061 taaaaatcgc cccactctct ttttgccgac gcagacgaat ggcgcggtta agccccggat
     6121 tagcactgat gatcgcctgc gcactgctta acgcctggct gctggtttca ctaccggtaa
     6181 aacgccagcc atattcatgt acgccaatca gcggataaat acagttcgca ccaacgccga
     6241 tatccagaat gctggcatta gctggaattg ttccgcttgc ttcggccagt aaatcggcaa
     6301 ggtgatgaat ataatccgcc cggcccggta ctggtgggca gagaaaaccg tccgggatat
     6361 cccagttcgc tacggcgtaa aaatgggcca gcaacgcctt attgagcgcc ttcaccgcca
     6421 gcggattggc aaagtctacg ctttgctccc cggcgggtgt aagcgtgagg aattgcctga
     6481 gttcaggatt gacctgacaa agcgtggcga gatcgtagcg gctgtgatga cggttgcgcg
     6541 gatgcaaccc cggtttctgg gcggacatag cattctcctt taagcagcgg cgtaagatac
     6601 ccgcataacg cgacagggta aatatctggc tgcgtttatc atttctaaaa accttcacat
     6661 ggctatggtt tatggcaatt caccataaaa aacatcatca tgcatgtcat tgatttgtct
     6721 tattttgtaa aaacacatcg ttcaaaaaat aagcgcatct ctgtcaattt tttgcgtcat
     6781 tttcatcgcg caggcgacct acacttatct ggcactaccc gttgtattta tgaggatgtc
     6841 attatgaaaa agtgcctcac actactgatt gccaccgtcc tgagcggaat ctctctcacg
     6901 gcttatgccg cgcaaccgat gagtaacctg gacagtggtc aactacggcc cgccggtacc
     6961 gtttcggcaa ctggcgcatc aaacctaagc gatctggagg ataaactggc agaaaaagcg
     7021 cgcgaacaag gcgcgaaagg ttatgtcatt aattccgcag gcggaaatga ccagatgttc
     7081 ggtactgcaa tcatctacaa ataaccccac caacgtaact gcattcgcct ctggatgcag
     7141 ttttcgtcca atttgtaagc aaaaaacatc aaatatgaac gcaatgtaaa taaatgtatt
     7201 tctttttcgc gcaatgggtg atagaaaatc gcgccaagtg ataatgctta tcaatattat
     7261 tatcacttgc acgtacgcta tcacgggatt aacagtggca tcgcatccgc agagatgctt
     7321 tctcgtgaca gtgaaaattt caccatataa gaaaaagtca cctgcaaaat ggaaaacaat
     7381 cgcaatttcc ctgccagaca atttcattcg ctcacgttct ttgccggtct ttgtattggt
     7441 attacgcctg tggcacaggc actcgctgcc gaagggcaag ctaacgcgga tgacacgctg
     7501 gttgtcgaag catcaacgcc ttcgctttat gcgccacaaa aatctgccga tccgaaattc
     7561 tcgcgtccgg tagcggatac tacccgcacg atgacagtga tttctgaaca agtgattaaa
     7621 gatcagggtg caaccaacct taccgacgcg ctcaaaaacg tccccggcgt gggtgcgttt
     7681 tttgcgggtg agaacggtaa ctccaccact ggcgacgcca tttatatgcg cggtgccgat
     7741 acctctaaca gtatttatat cgatggcatt cgcgatatcg gcagcgtctc gcgcgacacc
     7801 ttcaataccg agcaggtcga agtaattaaa gggccgtccg gcaccgacta cgggcgcagc
     7861 gcaccgacag gctcgatcaa tatgatcagc aaacagccgc gcaatgattc cggcattgac
     7921 gcctccgcca gtattggcag cgcctggttc cgccgcggca cgctggacgt caatcaggtc
     7981 attggtgata ccactgcggt gcgcctgaat gtaatgggcg aaaaaacgca cgatgccgga
     8041 cgcgacaaag tcaaaaatga gcgttacggc gtcgcccctt ctgtcgcttt tggccttggt
     8101 acagcgaatc gtttgtatct taattatctg catgtcaccc agcacaacac gccagacggc
     8161 ggcattccga ccatcggttt accgggtttt tctgccccat ctgcgggaac agcggccctg
     8221 aatcattccg gaaaagttga tacgcataac ttttacggca cggattccga ttacgacgat
     8281 tcgaccaccg acaccgctac catgcgtttt gagcacgaca tcaacgataa caccaccatt
     8341 cgcaacacta cgcgttggtc gcgcgtaaag caggattacc tgatgacggc gattatgggt
     8401 ggagcgtcga atattaccca gcccaccagc gatgtgaata gctggacgtg gtcacgcacg
     8461 gcgaatacca aagatgtgag taacaaaatt ctcaccaacc agaccaacct gacctcgacg
     8521 ttctataccg gcgctatcgg tcatgatgtc agtaccggcg tggaatttac ccgcgaaaca
     8581 cagactaact atggcgttaa tccggtgacg ttaccgacgg taaatattta tcatcctgac
     8641 agcagcattc atcccggcgg cctgacgcgc aacggcgcaa acgccaatgg tcagacggat
     8701 accttcgcaa tttatgcctt cgatacgctg caaatcaccc gtgattttga gctgaacggt
     8761 gggatccgtc tggataatta tcatactgaa tatgacagtg ccaccgcctg cggcggcagc
     8821 gggcgcggtg ccatcacctg ccctgctggc gtggcaaaag gttctccggt aaccaccgtc
     8881 gacaccgcca agtcgggcaa tctggtgaac tggaaagccg gggcgctgta tcacctgacg
     8941 gaaaacggca atgtttatat taactatgcc gtttcccagc agccgccggg cggcaacaac
     9001 ttcgcccttg cgcagtctgg cagcggtaac agtgccaacc gcaccgattt taaaccgcaa
     9061 aaagccaaca ccagcgagat tggcaccaaa tggcaggttc tggataaacg cctgctactt
     9121 accgccgcgc tgttccgtac tgatattgaa aatgaagttg agcaaaatga tgatgggact
     9181 tattcgcaat atggtaagaa acgtgtcgaa ggctatgaga tatccgtggc cgggaatatc
     9241 acccccgcgt ggcagatgat tggcggctat acccagcaaa aagcaactat caaaaacggc
     9301 aaagatgttg cccaggatgg ttcctcatcg ctgccgtata ccccggaaca cgccttcacc
     9361 ttatggagcc agtatcaggc aaccgatgat atttctgttg gtgcgggcgc acggtatatc
     9421 ggcagtatgc ataaaggttc agacggcgcg gtgggaacgc cagcatttac cgaaggttat
     9481 tgggtcgccg acgccaaact ggggtatcgg gttaatcgca atctcgactt ccagctaaac
     9541 gtctacaacc tgtttgatac cgattacgtc gcctcaatca ataagagcgg ctaccgttat
     9601 cacccgggcg agccaagaac cttcttgctc acagccaata tgcatttctg attcagatgt
     9661 ggggcgcagg ccccactttt tggagaactt gtatgatgta ccacattccc ggcgtgttat
     9721 cgccacagga cgtcgcccgt tttcgcgaac acctggaaca agccgaatgg gtggatggac
     9781 gcgtcaccac cggcgcacaa ggtgcgcaag ttaagaacaa tcaacaagta gacacccgca
     9841 gcgccctgta cgccgccctg caaaatgagg tgctgaacgc ggttaaccaa catgctttgt
     9901 tctttgccgc ggccttgccg cgtacccttt ccacgccgct gtttaatcgc tatcagaaca
     9961 atgaaaccta tggttttcat gtggatggcg cagtacgcag ccatccacaa aacggctgga
    10021 tgcgcactga cctttctgcc acgctgtttt taagcgatcc agaaagctac gacggcggcg
    10081 aactggtcgt taatgacacc ttcgggcaac atcgggtaaa actcccggca ggcgatctgg
    10141 tgttgtatcc ctccagcagc ctgcattgcg tgacacccgt aacccgcggc gtgcgagtgg
    10201 catcatttat gtggatccag tcgatgatcc gcgatgataa aaagcgcgcc atgctgtttg
    10261 aactggacaa caatattcag tcgctgaaaa gccactacgg cgaaagtgaa gagatcctgt
    10321 cgctgctcaa tctttatcat aatctgctgc gggaatggtc ggagatctga cgcttgaact
    10381 gcccgagttc gtccctatat tagctacact taactgtaca agcattgata tggggaggac
    10441 gatatggcat ccggttgggc taatgatgac gccgtcaacg aacagatcaa cagtacaatt
    10501 gaagatgcga ttgcccgcgc tcggggtgaa attccgcgtg gcgaaagcct gtatgaatgt
    10561 gaagagtgcg gtgcccctat cccgcaggcc cgtcgggaag ccattcctgg cgtgcgctta
    10621 tgcattcatt gtcagcagga gaaagattta caaaaaccag cttatacagg atataatcgc
    10681 agaggttcga aagacagcca gttacgttaa ctacaactgg cgggatgtat agcgaatata
    10741 atttgtattt tgcgtggcat tccgtgcctt taacgctacc gtgactgcca cgcggtataa
    10801 aacaagtcca taagtacaac aaataaatgg tttatcagta tgttagatat caatcaattt
    10861 atttgaacaa ggtggtcaat tctcttcgat tttatctctc gtaaaaaaac gtgatactca
    10921 tcacatcgac gaaacaacgt cacttataca aaaatcacct gcgagagatt aattatgaaa
    10981 actatcaata ctgttgttgc tgctatggct ctttcaactc tgtcatttgg cgtgttcgcg
    11041 gcggaaccgg taacggcatc ccaggcacag aacatgaata aaatcggcgt ggtttctgcc
    11101 gatggcgcat ccaccctcga tgccctggaa gcgaaactgg ctgagaaagc cgcggcggcc
    11161 ggtgccagtg gatacagcat cacttctgcc accaacaaca ataaattaag cggtactgcg
    11221 gtaatttata agtaattcgt aagctggatc aggcgtttac gctacgttca gcacaagtat
    11281 ttccctgtct gtttgccgac agacgcatat gctctaaccc tcatgatcct atgttaccct
    11341 tgtttgcccg tccgccactg gacgggcttt ttttagctgg ctagctgctg acagaaagcc
    11401 tgcaacgtct cttccggcat accaatctgc cgcgccgcat cacaaatggc ctgccagctt
    11461 cccgcatcca gtggaatccc ctgctcctgc cgttcgcgac gcgtgttcac ttcccactcg
    11521 cccggtagca aaatcggctt atcgtcatca tgcggcgagg ctttcaccca ctcggcaaag
    11581 gcttcggtct gcgcactaca atccggcgcg ccgaacagtt ccgggttgat aatgatagtg
    11641 gtcatgcagt taagaatggc atcgggactg gtttgtaacg tttcctgatg cgtcgtttta
    11701 ccgccagaaa gcgccccgcc aagaatttca cacatcgctg caagggcgta gcctttatgt
    11761 tcggcaaagg tcaacagcga acccaacggc gactcctgca ttaccgccgg atttgtcgtc
    11821 ggcacgccgt taacgtcaat caggcaacct ggcggcacgg ggacgccttt atgccaggcg
    11881 acgcgggttt tgccaaatgc aatggcgctg gtggcgtaat cgagcaacag cgggaaatta
    11941 tctttacgag ggaaaaccac acagaacgga ttggtgccaa agcggctgtc gcgaccgtgg
    12001 aacggcgcga ccattggaat accgaccacg ctaacaaagt ggatagagac aaaccccgcc
    12061 gctgcacact gctccgccca gtaaccgata cggccgatat gatgcgagtt atgtagcgcc
    12121 acggcggcaa tgccgtgctg atgcgctttc tcaatcccca gcgccatcgc ttcgtgtgcc
    12181 gcgacctgac caaatgcgcg atcgccatcg agcgtgaccg ccgcccccgc ttctttaacg
    12241 actttggcat gatggttaat ttgcagatgc ccctgactcc aggagcgcac atagcttggg
    12301 atcatgccaa taccatgtga atcatgccct gccaggtttg ccgcgatcaa atgatcggcg
    12361 actaatttcg cttcctgttc ctcactaccc atctgacgaa atacagcctg aataaaactg
    12421 tgcagcgtct gagcatcaaa gcgatggcca ctttccatgg ttaactcctg tttatgttat
    12481 gtgtttgttg ttttttatgc tgcacgccgg gcgcgggaag gtcaataaag atgcaggaat
    12541 ttcatattgc ggtggggtaa aagccggatg acatggctca tccggctgag ataaaaatta
    12601 aaatgcctga ttaacgcgcg ccaggccgtc gctgatagtt gccgcttcac ccgtagccat
    12661 caggcagcaa gccatctgga ttttcagcga ttcgggaatc ggttcgctgc cagccaggca
    12721 acgctcaatc cactgcgccg tggtttccgg atcttttgct tgtggcagta actcgctacc
    12781 agcagtgtcc tgtttttcat acagtacccg catcccttca cggtcaatga gattgatctg
    12841 cgggcagcgc tgcggattag catacacttc accttcagta ccatgcataa gtagcgcccg
    12901 cccgccgata tcgctaaaga acttcgcgac gcgtccaatg tattccggat gcgaaacgct
    12961 ggaaagacgc agtgcctcac cttcggcaaa tggcgtcgcc agtttcgcca gggtatgtgc
    13021 actgttacgc acgcccatcc gccagcgcat cgccagttgt ttttccagcg gcgggcaaaa
    13081 cgcgccgaca ggcataaaga caggttgatg ttcgtcgagc ttcgcctgcg cctgcccgcc
    13141 gtgcaacgtt ggcgtaatac ccatcagttc gaaaatggtt tcggtcagca cgcgggttgg
    13201 atcttcgcta accccgtgaa ccaccacagg aaaaccgagt ttgtgcagca gaatcgccag
    13261 caacggcgtc aggttggcct gtttacgcgc gccgttgtaa ctggggatga caatcggcat
    13321 cggcttgcct gcaggcggcg tcagcttgat ggtgtgattt tgcatggctt cgtaaaagcc
    13381 gagcatctct gcttcccctt cccctttgat acgtagcgca atcaatacgc cgcccaactc
    13441 aaggtcaggg acttcaccat tgagcatatg ggcatacaga ccgcgcgcag tatcccggtc
    13501 taaatcgcgc gcgtggtttt tcccgcgccc gatctcttta atgattttgc gatagtccat
    13561 ttacgactcc ttacctgact cacatcatta acgccgccga cggcgtgggg atttcgtttt
    13621 ttctttcttt ttaactatac cttcagggac ttccggttgc tctatcggaa ataccggtaa
    13681 tgcatccagt agtcgcttgc cataattttt tgtcagcaag cgtttgtcgt agataaccac
    13741 ttccccccag caaccgtggc ttcgaatcag tcgcccaacc tgctgaatca ggttaaacga
    13801 agcgctcggc aggctttgca cctcaaacgg atagcggtta aggcttttca gccattcacc
    13861 ttcggtgatc accaccggac tgtcgatggg cggaaaagcg attttgtgga tatgcacctg
    13921 gctgagcaga gcgcctttca gatcaagacc ttcggcaaag gactgtaagc ccaccagcac
    13981 gctacgctca ccgttggcaa cgcgtttgcg gtgcagttca actaagcgat aacgtggctg
    14041 atcgccctgc accagcaaca tcaggcgtaa atccgtcaca tagtcgagaa agcgctgcat
    14101 cgcacgcccg ctggcaaaca gcaccaacat accgagatgt tttttgctct ccacctgctc
    14161 acggaaaaag gccgccattt cagcaatgtg ctgttcttcg ttgtcgatgg aaggctcaac
    14221 gcgcatccgg ggaataacaa ttttgccctg ttcgcagtgg ttaaagggcg aatccagcgc
    14281 cacaaagcgg tcacccgctt tctctttcag cccactcatc tcctgcaaac gcgaaaaact
    14341 gttcagcgaa cgcaaggttg cggaggtaac aataatgtgc ggaatactgc gccacagcag
    14401 cctttccagt tggtcgctaa cacgaatacc cacacagtga aaccacagat gtagctgccc
    14461 ttcgcgctct tcccgcgtcg cccatttggt caccggcgca ccggaagatt gcgccagaga
    14521 cgccagccgc cagagtttgc tttgcgcctc gaacatcccc aacgcgcggt tcatctgcaa
    14581 aatcaaccga tgcaggcgta caatgtcatg gctgccggtt ttctcactta aatcgttaag
    14641 aaataactcc gccagaccac gcagcatctc ggtgagtttt gccagccgct ggcagatctc
    14701 cagcacttca tcaggcagtt cgcccatcgc aaaacggtgc tctgcctcct gcccggcagg
    14761 catgtagaga ttgagaatgt tgtttaacga ggcgataagc tcatacagct cttcacaatg
    14821 cgcattcaaa cgttcaggga tcgccagcgg tgggatggtc ttcgggcgaa actgctccat
    14881 gcaggtggcg accagtttgg tgaacaggtc cagttggagc cggtaccagg gcgcagtgat
    14941 ttcggcgctc atctccagcg catcccgcgc cacatccggc aggtgatgac cttcgtccag
    15001 caccagcagt aaatttttcg ggtcaggcaa taccgcttcg ctttccattg ccgccatcac
    15061 cagcgcatgg tttgccacca ccacttccgc ttcctgaatt tcccgacgag cgacaaaaaa
    15121 cgggcattcg cgatagtagt aacagttgcg gttgaggcag ctggctttgt cggtactcaa
    15181 acgacgccag agatcatcat ctatagcgat atcagtatga tcgcgcaggc catcccattt
    15241 ataagtgtcg agatcgccct tcagcttcgc acaacgtttt tgctcttcct gattgttcgg
    15301 cgtcagttcg tcgtcaagaa acgccagcag atcctgttgc gtgggctcag tgctggcgag
    15361 cgctgtcaga ttacgcgggc aaacgtagcg cccacgccca aaagcggcag tgaatttaag
    15421 atcgggaatg atctttttca gcagcggtaa atctttgctg tagatctgat cctgcaatgc
    15481 cacgttggcg gtacttacca ccagcgtttt ttgctcttcg cgggcaatgg cgatgccggg
    15541 gatcaaatag gagagcgttt tcccaacgcc ggtaggagct tcaatcgcca gatgccgccc
    15601 ttcttctccg gccagcgttt tggcgacgtc cgcaatcatc tgccgctgcg gcgcacgggg
    15661 aataaagtcg gggatctgtt cctgaagcgc cttataccag gcggcaattt gcgctttaag
    15721 cgcggcggtt aatgccatga gaaaacctga aatactgtat aaacagccaa tattgtggca
    15781 tttttcggtt ttcaggggta atggtttttc tgtttctgga aagcggctcg caataaccag
    15841 caggatgatg cgtaaagcgc ttcgcgctaa attcgaacaa catgcagaac tgcgtacact
    15901 cttgctggca accgcgtccg caaaactggt tgagcatacg caaaatgatg cttactgggg
    15961 agatggcggt aatggtcagg gcaagaatcg cctggggtac cttttaatgg cgttgcgcgg
    16021 acaattggct gcggagaagt aacgcatcgg gtggcttgtg ggcgttaaaa cagagaaatc
    16081 tttttgccgc gctcgcaaat ggctgacaag tgcttgttgt gaaatgccgg atgcggcgcg
    16141 agcgccttat ccggcctaca aaaacatgca cattcaatat attgcagagt tcacgtaggc
    16201 ctgataagcg tagcgtatca ggcagttttg tgtttgtcat cagtctcatg ccgggcatag
    16261 cccggcataa aagattactg cgcagcggca ggtttacgcg gacggcggcg acgttgttgt
    16321 tcgcctgccg gtttggcatc gccgagacga cgagacggtt tttctgcggg cttcgcgtta
    16381 ccagacttcg caccactttc cgcacggcgt ggttgctgtt gaccgcgacc accgccctgt
    16441 ccacgaccgc cgccacgttg ctggcgaccg ttttggatcg gttcggcttt gattgacggg
    16501 tccggctcat agcccagaat cgcaatgcgc gggatctctt ttttcagcag tttttcgata
    16561 tcacgcagca gtttgtgttc atcaacacac accagcgaca atgcttcgcc agttgccgcc
    16621 gcacggccag tacgcccgat acggtgaaca taatcttccg gtacgtttgg taactcatag
    16681 ttgacgacgt gcggcaactc ttcgatatcc agaccacgcg cagcgatgtc agttgccacc
    16741 agtacacgaa tatcgcccga tttaaaatcg gccagcgcac gagtacgcgc accttgcgat
    16801 ttattaccgt ggatcgccgc actacggatg ccatctttat taagctgttc agccagatgg
    16861 ttagcgccat gtttggtacg ggtaaacacc agcacctgct gccagttccc tttcccaatc
    16921 atatgcgaca gcaattcgcg tttgcgtttc ttatcgacaa agtgaacgtg ctgggtcacc
    16981 tgatcagacg cagtattgcg gcgtgccact tcgatttcca gcgggttgtg caacagtttt
    17041 tccgccaggg ctttaatatc gtcagagaag gtcgcggaga acaacaggtt ctggcgcttc
    17101 gctggcagtt ttgttaacac gcgacggata tcgtggataa agcccatgtc gagcatgcgg
    17161 tcagcttcat caaggacgag gatttcaacc tgatccagct tcactgcatt ttgatgttcc
    17221 aggtccagca gacgtcccgg cgttgccacc agcacatcaa cgccgccgcg cagcttcatc
    17281 atctgcgggt taatgctgac accgccaaac accaccagcg aacgaatgtt caggtatttg
    17341 ctgtaatcac ggacgttttc gccaatctgc gccgccagtt cacgggtcgg ggtaagaatg
    17401 agcgcacgca ccggacgacg ccctttggcg tgcggctggc gagtgatcag gtgttgcaac
    17461 agcggcagcg taaagcccgc tgttttacct gtaccggtct gggcgctggc catcaggtcg
    17521 cggccttcca gcaccgcagg gatcgcctgc tgctgaatag gggtgggttc acggtaaccc
    17581 tgctcggcaa cggcgcgcag gatatcaggg cttaaaccca aagaatcgaa agacataact
    17641 actccgaacc gccccgaccg ttaccggtgt agttttcagg gagatactga aaaggaaaat
    17701 gacaaaaacc acaatgtcat gagggagcgg agtgtagcag tttttgtgac gcagcgcata
    17761 aattatccct gtgactggcg tagctaaaat tcttagccat actggacaac tcccctatgg
    17821 agtcataatc ttaatcaatc atttgattaa gaatggactg tgcgatgaat aatcctgcca
    17881 tgacaatcaa gggtgaacag gcgaaaaaac agctgattgc tgcggcactg gcacagtttg
    17941 gtgaatatgg aatgaacgcc accacccgcg agatagccgc ccaggccggg cagaatatcg
    18001 ctgccatcac ctactacttc ggttcgaaag aagatttgta cctcgcctgc gcccagtgga
    18061 ttgctgattt tattggcgag cagttccgtc cgcacgccga agaagccgaa cgtttgttcg
    18121 cgcaaccaca gccggatcgg gctgccatcc gtgaactgat ccttcgcgcc tgcagaaaca
    18181 tgattaagct gctcacccag gatgacaccg tcaacctcag caaatttatc tcccgtgagc
    18241 agctctctcc cacggcagcc taccacctgg tgcacgaaca ggtgattagt ccgctacaca
    18301 gtcaccttac acgcctgatt gccgcctgga ccggctgcga cgctagcgat acccgcatga
    18361 tccttcatac ccatgcgttg attggtgaga ttctggcgtt tcgtcttggc aaagaaacta
    18421 ttctgttacg taccggctgg accgcgttcg atgaagaaaa gaccgaactg atcaaccaga
    18481 cggtgacctg tcatattgac ctgattttgc aaggattatc gcaaaggagt ttgtagtgat
    18541 gaaaaaacct gtcgtgatcg gactggcggt agtagtactt gccgccgtgg ttgccggagg
    18601 ctactggtgg tatcaaagcc gccaggataa cggcctgacg ctgtatggca acgtggatat
    18661 tcgtacggtg aatcttagtt tccgtgttgg ggggcgcgtt gagtcgctgg cggtggacga
    18721 aggtgatgcg atcaaagcgg gccaggtgct gggcgaactg gatcacaagc cgtatgagat
    18781 tgccctgatg caggcgaaag cgggtgtttc ggtggctcag gcgcagtatg acctgatgct
    18841 tgccgggtat cgagatgaag aaatcgctca ggccgccgca gcggtgaaac aggcgcaagc
    18901 tgcctatgac tatgcgcaga acttctataa ccgccagcaa ggactgtgga aaagccgcac
    18961 catttcggca aatgacctag aaaatgcccg ctcctcgcgc gaccaggcgc aggccacgct
    19021 gaaatcagcg caggataaat tgcgtcagta ccgttccggt aaccgcgaac aggacatcgc
    19081 ccaggcgaaa gccagcctcg aacaagcaca ggcgcaactg gcgcaggcgg agctgaattt
    19141 gcaggactca acgttgatag caccgtctga tggcacgctg ttaacgcgcg ctgtagagcc
    19201 aggcacggtg cttaatgaag gtggcacggt atttaccgtc tcgctgacgc gtccggtgtg
    19261 ggtacgcgcc tatgttgatg aacgtaatct tgaccaggcc cagccggggc gcaaagtgtt
    19321 gctttatacc gatggtcgcc cggacaagcc gtatcacggg cagattggtt tcgtttcgcc
    19381 gactgctgaa tttaccccga aaaccgtcga aacaccggat ctgcgtaccg acctcgtcta
    19441 tcgcctgcgt attgtggtga ccgacgccga tgatgcgtta cgccagggaa tgccggtaac
    19501 ggtgcaattc ggtgacgagg caggacatga atgatgccgt tatcacgctg aacggcctgg
    19561 aaaaacgctt tccgggcatg gacaagcccg ccgtcgcacc gctcgactgc accattcacg
    19621 ccggttatgt gacggggctg gttgggccgg acggtgcggg caaaaccacg ctgatgcgga
    19681 tgctggcggg attactgaaa cccgacagcg gcagtgccac ggtgattggc tttgatccga
    19741 tcaaaaacga cggcgcgctg cacgccgtgc tcggctatat gccgcagaaa ttcggcctgt
    19801 atgaagatct gacggtgatg gagaacctca atctgtacgc ggatttgcgc agcgtcaccg
    19861 gcgaggcacg gaagcaaact tttgctcgcc tgctggagtt tacgtctctt ggcccgttta
    19921 ccggacgcct ggcgggcaag ctctccggtg ggatgaaaca aaaacttggc ctggcctgta
    19981 ccctggtggg cgaaccgaaa gtgttgctgc tcgatgaacc cggcgtcggc gttgacccta
    20041 tctcacggcg cgaactgtgg cagatggtgc atgagctggc gggcgaaggg atgttaatcc
    20101 tctggagtac ctcgtatctc gacgaagccg agcagtgccg tgacgtgtta ctgatgaacg
    20161 aaggcgagct gctgtatcag ggagaaccga cggccctgac tcaaaccatg gccggacgca
    20221 gctttctgat gaccagcccg cacgagggca accgcaaact gttgcaacgg gcattgaaac
    20281 tgccgcaggt cagcgacggc atgattcagg ggaaatcggt acgtctgatc ctcaaaaaag
    20341 agaccacacc agacgatatt cgccatgccg acgggatgcc ggaaatcaac attaacgaaa
    20401 ctacgccacg ttttgaagat gcgtttattg atttgctggg cggtgccgga acctcggaat
    20461 cgccgctggg cgcaatattg catacggtgg aaggtacacc tggcgagacg gtgatcgaag
    20521 cgaaagagct gaccaaaaag tttggcgatt ttgccgccac cgatcacgtc aactttgccg
    20581 tcaaacgcgg tgaaatcttt ggtttgctcg ggccaaacgg cgcagggaaa tcgaccacct
    20641 ttaagatgat gtgcggtttg ctggtaccga cctctggtca ggcgctggtg ctgggcatgg
    20701 atctgaaaga gagttccggt aaagcgcgcc agcatctcgg ctatatggcg caaaaatttt
    20761 cgctctacgg caacctgacg gtcgaacaga atttacgctt tttctctggt gtgtatggct
    20821 tacgcggtcg ggcgcagaac gaaaaaatct cccgtatgag cgaggcgttc ggcctgaaaa
    20881 gtatcgcctc ccacgcgacc gatgaactgc cattaggttt taaacagcgg ctggcgctgg
    20941 cctgttcgct gatgcatgaa ccggacattc tgtttctcga cgaaccgacg tccggcgttg
    21001 atcccctcac ccgccgtgaa ttttggctac atatcaacag tatggtagag aaaggcgtca
    21061 cggtgatggt caccacccac tttatggatg aagcggaata ttgcgaccgc atcggcctgg
    21121 tgtaccgcgg gaaattaatc gccagcggca caccggacga tttgaaagcg cagtcggcca
    21181 acgatgagca acccgatccc acgatggagc aagcctttat tcagttgatc cacgactggg
    21241 ataaggagca tagcaatgag taatccgatc ctgtcctggc gtcgcgtgcg ggcgctgtgc
    21301 gtcaaagaga cgcggcagat cgttcgcgat ccgagtagct ggctgattgc agtagtgatc
    21361 ccactgctac tgctgtttat ttttggatac ggcattaacc tcgactccag caagctgcgc
    21421 gtcgggattt tactggaaca acgtagcgaa gcggcgctgg atttcaccca caccatgacc
    21481 ggttcgccct acatcgacgc caccatcagc gataaccgtc aggaactgat cgccaaaatg
    21541 caggcgggga aaattcgcgg tctggtggtt attccggtgg atttcgccga acagatggag
    21601 cgcgccaacg ccatcgcacc gattcaggtg attaccgacg gcagtgagcc gaataccgct
    21661 aactttgtgc aggggtatgt cgaagggatc tggcagatct ggcaaatgca gcgagcggag
    21721 gataacgggc agacttttga accgcttatt gatgtacaaa cccgctactg gtttaacccg
    21781 gcggcgataa gccagcactt tattatcccc ggtgcggtga ctattatcat gacggtcatc
    21841 ggtgcgattc tcacctcgct ggtggtggcg cgagaatggg aacgcggcac catggaggct
    21901 ttgctctcta cggagattac ccgcacggag ctgctgctgt gtaagctgat cccttattac
    21961 tttctcggga tgctggcgat gttgctgtgt atgctggtgt cggtgtttat tctcggcgtg
    22021 ccgtatcgcg ggtcgctgct gattctgttt tttatctcca gcctgttttt actcagtacc
    22081 ctggggatgg ggctgctgat ttccacgatt acccgcaacc agttcaacgc cgctcaggtg
    22141 gccctgaacg cggcttttct gccgtcgatt atgctttccg gctttatatt tcagatagac
    22201 agtatgcccg cggtgatccg cgcggtgacg tacattattc ccgcacgtta tttcgtcagc
    22261 actctgcaaa gcctgttcct cgccgggaat attccagtgg tgctgatagt gaacgtgctg
    22321 tttttgatcg cttcggcggt gatgtttatc ggcctgacgt ggctgaaaac caaacgtcgg
    22381 ctggattagg gagaagagca tgtttcatcg cttatggacg ttaatccgca aagagttgca
    22441 gtcgctgctg cgcgaaccgc aaacccgcgc aattctgatt ttacccgtgc tgattcaggt
    22501 gatcctgttc ccgttcgccg ccacgctgga agtgaccaac gccaccatcg ccatctacga
    22561 tgaagataac ggcgagcact cagtagaact tactcaacgt tttgcccgcg ccagcgcctt
    22621 tacccatgtg ctgctgctga aaagcccgca ggagatccgc ccgaccatcg acacacaaaa
    22681 ggcgttacta ctggtgcgtt tcccggctga cttctcgcgc aaactggata ccttccagac
    22741 cgcgccgttg cagttgatcc tcgacgggcg taactccaac agtgcgcaaa ttgccgccaa
    22801 ctacctgcaa cagatcgtca aaaattatca gcaggagctg ctggaaggaa aaccgaaacc
    22861 caacaacagc gagctggtgg tacgcaactg gtataacccg aatctcgact acaaatggtt
    22921 tgtggtgccg tcgctgatcg ccatgatcac cactatcggc gtaatgatcg tcacttcact
    22981 ttccgtcgcc cgcgaacgtg aacaaggtac gctcgatcag ttgctggttt cgcccctcac
    23041 cacctggcag atattcatcg gcaaagccgt accggcatta attgtcgcca ccttccaggc
    23101 caccattgtg ctggcgattg gtatctgggc gtatcaaatc cccttcgccg gatcgctggc
    23161 gctgttctac tttacgatgg tgatttacgg tttatcgctg gtgggattcg gtctgttgat
    23221 ttcatcactc tgttcaacac aacagcaggc gtttatcggc gtgtttgtct ttatgatgcc
    23281 cgccattctc ctttccggtt acgtttcgcc ggtggaaaac atgccagtgt ggctgcaaaa
    23341 tctgacgtgg attaacccta ttcgccactt tacggacatt accaagcaga tttatttgaa
    23401 ggatgcaagt ctggatattg tgtggaatag tttgtggccg ctactggtga taacggccac
    23461 gacagggtca gcggcgtacg cgatgtttag acgtaaggtg atgtaacttc ttatctttcg
    23521 ccagcaaaga caccaccgcc gggccggcaa ggattgccag ccctgcaatt gccagcaaaa
    23581 agttgttttc cagtacgcgg gacaacagcc acagcacaat cagcgctgca ccaaaatacc
    23641 aggtcgtggt cagctcttcc agcacgtctg ccacctcacg ccagcgttgc tctgggtggc
    23701 gctgaaacac cagcatcatc actaccgtga cacaatacag tgcgcataat cctacgccga
    23761 cgtgaaccag agttttactc atccaaccca ccaccagcag cgccactacc agtaaatgca
    23821 acataatctg ccagcaactt aggccagttg cgacacgaac acgttgttgc cacttcatgg
    23881 cttctctcct gaagaattta tctctactta ttcagagtac cgaactttac ggaaaattcc
    23941 gtaagaccgc acctttttgt gacgccgact acactatttc aatgagataa gaggcaaaga
    24001 caggaaaatt atgcccgatc aaacacaaca attttcgttc aaggtgctca ccatcaatat
    24061 tcacaaaggc tttaccgcgt ttaaccgacg cttcatttta ccggaacttc gcgacgccgt
    24121 gcgtaccgtc agcgccgata ttgtttgcct gcaggaagtg atgggcgcgc acgaagttca
    24181 tccgctgcat gtggaaaact ggcccgatac ctcgcactac gagtttctcg ccgacaccat
    24241 gtggagcgat ttcgcctacg gtcgcaatgc cgtatacccg gaaggacatc acggtaacgc
    24301 cgttctttca cgttatccca ttgaacatta tgagaatcgt gatgtttcgg tcgatggtgc
    24361 ggaaaagcgc ggcgtgctct actgccgcat tgtgccgccg atgaccggga aagcgattca
    24421 tgtgatgtgc gtacatctgg gcctacgtga ggcgcaccgt caggcgcagc ttgcgatgct
    24481 cgccgaatgg gtgaatgagc taccggacgg cgaatcggta ttggtagcgg gtgatttcaa
    24541 cgactggcgg caaaaagcta atcatccgtt aaaagtgctg gccgggctgg atgagatttt
    24601 tacccgcgcc cacggacgtc cggcgcgcac gtttccggtg caatttcctc tactacgact
    24661 ggacaggatc tacgtcaaaa atgccagcgc cagcgcgcca accgcgttgc cgctgcggac
    24721 atggcgacac ctttctgatc atgccccttt aagtgcggag attcatttat gaaatgtagc
    24781 tggcgcgaag gcaatatgat ccagttgctg gaaaacggcg agcaatatta tcccgcggtg
    24841 tttaaggcga ttggcgaggc gcaagaacgc atcattcttg aaacgtttat ctggtttgag
    24901 gatgacgtcg gcaaacagct gcatgcggcg ctattggcag cagcgcaacg cggggtaaaa
    24961 gcggaagtct tgctggatgg ctacggttcg ccggatctca gcgatgaatt tgtcaatgaa
    25021 ctgacggcag ctggcgtggt gttccgctac tacgatcccc gccctcgcct ttttggtatg
    25081 cgcaccaatg tgtttcgccg gatgcatcgc aaaattgtgg tgatcgacgc gcgtatcgcc
    25141 tttattggcg ggctgaatta ctccgccgag catatgtcca gctacggccc ggaggccaaa
    25201 caggattacg cggtacgcct cgaagggccg attgtcgaag atattctcca gtttgagctg
    25261 gaaaacctgc caggacaaag cacggcgcga cgctggtggc gacgccatca taaagcggaa
    25321 gagaaccgcc agccgggaga agcgcaggta ttgctggtct ggcgcgataa cgaagaacat
    25381 cgcgatgata tcgaacgtca ctatctgaaa atgctcactc aggcgcggcg ggaagtgatt
    25441 atcgccaacg cctacttctt ccccggctat cgttttttac acgccttgcg taaagcggca
    25501 cgacgcgggg tgcggatcaa actgatcatt cagggcgaac cggatatgcc gattgtcaga
    25561 gtcggcgcgc gtttgctgta taactatctg gttaaaggtg gcgttcaggt gtttgagtac
    25621 cgccgccgcc cgctccacgg caaagtggca ttgatggacg atcactgggc gacagtaggg
    25681 tccagtaatc tcgatccgct cagtttgtca ctgaatctcg aagcaaatgt catcatccac
    25741 gatcgtaatt ttaaccagac gctgcgcgat aatctgaacg gcattatcgc cgcagattgt
    25801 cagcaggtcg atgagaccat gctgccgaaa cgcacctggt ggaacctgac taaaagcgtg
    25861 ctggcgttcc actttctacg ccacttcccg gcgctggtgg gctggcttcc ggcgcacacg
    25921 ccacgtctgg cgcaggttga tccccccgca caaccgacaa tggaaacgca ggatcgggta
    25981 gaaactgaaa acacgggggt aaaaccctga tgagtaaatc acacccgcgc tggcgcttag
    26041 caaagaagat cctcacctgg ctgtttttta tcgcggtgat tgtgttgttg gtggtctacg
    26101 ccaaaaaagt ggactgggaa gaggtctgga aggtcatccg agactacaat cgcgttgcac
    26161 tgctcagtgc ggtcgggctg gtggtcgtca gctatctgat ttacggttgc tacgacctgc
    26221 tcgcccgttt ctactgcggt cacaaactgg cgaagcgcca ggtgatgctg gtgtcgttta
    26281 tctgctacgc cttcaacctg acactcagta cctgggtcgg cggcattggt atgcgctatc
    26341 gtttgtactc ccgactgggg ttaccgggca gcactattac gcggattttt tcgctcagta
    26401 ttaccaccaa ctggctaggc tatattttgc tagcgggggt tatctttacc gcaggcgtgg
    26461 tggagttgcc ggatcactgg tatgtcgatc aaactacgct gcgtattctc ggcattggct
    26521 tactgatgat tatcgcggtt tatttgtggt tttgcgcttt cgcgaagcac cgccatatga
    26581 ccatcaaagg gcaaaagctg gtgctgcctt cgtggaaatt cgccctcgcc cagatgctga
    26641 tttccagcgt taactggatg gtaatgggag cgattatctg gctgttactt ggtcaaagcg
    26701 taagctattt ctttgtactg ggcgtgttgc tggttagtag tattgctggc gtcatcgtgc
    26761 atattccggc gggaattggt gtgctggaag cggtgtttat cgcgctactg gctggggagc
    26821 atacctccaa aggcacaatt atcgccgccc tacttgctta ccgtgtgctg tattacttta
    26881 tcccactgct gctggcgctg atctgttacc tgttgctgga aagccaggcg aagaagctac
    26941 gggcgaaaaa tgaagcggcg atgtgaagta tagttaagtt ctttagtatg tgcatttacg
    27001 gctaatgaaa aaaccgcgta tgcctttgcc agacaagcgt tatagctata gcagcaagaa
    27061 tcccaaagaa accgataaaa tagtaataga gtgttaatgc acctataaaa gcacaacgaa
    27121 ccggactcca taattcttca ctatggcttt ttcctgtcag ttcaaggagc ttatttcgtc
    27181 catgcgagat aatgcctgac cataagacaa tcattaagca acttattacc caaatgggtc
    27241 gttcactcat taatgtggca ttcacgatga ttaccagggc caaccctgtc aacgtcatca
    27301 taatgataaa acgatgagaa ccaggatcaa atttaaacaa tagacctgcc agcatactga
    27361 ttaaaaacat cgatcccgca gtgctgaaca cgacgataat ggcagataca ggcgctaaac
    27421 tcgcaacgac aatcgccacc aaagagatta aaaacaaata tattacgccc gcgatggcgg
    27481 tatttatctt gttgatatct ttacttaagc catacataga aagtaataat aatcctatag
    27541 caacatacat ttgcggtgaa tcatattttg ttgccgtaat ttcgagatac ttagcgcccc
    27601 aggccagccc tgcggttgcc accaaaccca aagcggtaat gagccatatg ccgtttaata
    27661 tcctggcttc gtgctgaaaa tctaatttat tgctattttg cgagtatgat tccattcttt
    27721 tagttgtcct tagaaaaaac attaatattc accatcaata aatttaaaac cacgcataca
    27781 aaatactttt gcatttatgg atacagaaaa cgcttccgct cgtccataag gcatatttta
    27841 tacctggtac ttgttaagtg tcgtttttaa taagaaaaaa aatcccgaca catggccggg
    27901 atattgatga tgaaaaagaa ttaacggcgg ttgccgaaga tccgcagcaa catcaggaac
    27961 aggttgatga agtccagata caaggttaac gcgccaagaa tggaatattt gcgcaggttc
    28021 gacgtgtcgc gagtatcaat ctgctcaccc atatttttca gtttctgggt gtcatacgcc
    28081 gtcaatccga caaagacaat cacgccgatg taggtgactg cccacatcaa tgcttcgctt
    28141 ttcagccaga agttaaccag cgatgccagc acaatgccga ttaacgccat aaacagcata
    28201 ttgccaaagc cgcttagatc gcgcttcgtg gtgtaaccgt acaggctcat tgcgccgaac
    28261 atcccggcag taacgacgaa agtactggcg atagaagcag cggtatagac aatgaaaata
    28321 ctggaaagcg taagacccgt cagcgccgaa taaagcataa agagcatcgt cgttacacct
    28381 gcgctcagct tttgaatcat cgctgataac acaataacca atgctaattg cgcgatgatc
    28441 agaccgatta aaaagacacg gttagtaaac aacagctcca tcacggccgc ggaattagcc
    28501 gcataccagg caacaaatgc tgtcagcaac aagccaacgg tcatccagcc atagacttgc
    28561 gccatataag tttgcaagcc agcccggggt tgtacgattg aatcagaacg tgggaatctg
    28621 tccatgactt tctcctgaag atataaggaa tatcttaagg atactgcaaa atgatgaggc
    28681 tgtgcatcga cgcagcgtaa acggatgtac tgagcggtga aattgccgga cgcagcggtg
    28741 ccttatccgg ctaacaataa actaccagcg ttttgccgcc tgctgatcgc tctcccgagc
    28801 ttcgacccag cggtcgcctt ccggcgtggc ttcgcgcttc cagaacggtg cgcgggtttt
    28861 gagataatcc ataataaact gcccggcttc aaacgcactg ctgcgatgcg cactggtaac
    28921 accgacaaaa acaatttcat cgcccggcca taattcacca atgcggtgaa ttaccgtgac
    28981 gcgccccagc ggccagcggt tacgcgcttc atcaacgatt tctgccagtg ctttttctgt
    29041 cattcccgga tagtgttcga gggttaatgc tttgacgctg tcgcccaggt tatggttgcg
    29101 caccttaccg gtaaaggtga ctaccgcacc gtcttcgtca cgctcagcca gccacgggta
    29161 ctcttctcct acgctgaacg gctgcgggcc gacaacaatt ttggtttctg ccatcttaac
    29221 ctccggttac cggcgggaag aaagccactt cgtcgccgtc agtcagcgaa tggtcaaaac
    29281 tcaccagcgt ctggttgaca gcagccagca atttgccatc ttccagcgcc agagcccagc
    29341 gatcgctctg cgcagccaga tgctggcgta acgcttcaac ggttgggaaa tccgcagcca
    29401 cttcggttgc atcagttccc accaactcgc gcacctgggc gaaaaaaaga acgttaatca
    29461 tccgcttcca ccttaaagtc acccgacttg ccgccgctct ttgccagcaa acgtaccgga
    29521 ccaatcacca tatctttttg caccgctttg cacatgtcat aaatggtcag cgccgccacg
    29581 gaggccgcgg ttaacgcttc catttcgaca ccggttttcc cggtcaggcg gcataaggtt
    29641 tctatacgta cccgattgtg ctccggctcg gcctgtaaat tgacttcaac tttgctgagc
    29701 atcagcgggt gacacagcgg gatcagatcc caggtgcgtt ttgccgcctg aataccggcg
    29761 atacgcgcag tggcaaatac gtcgcctttg tggtggcgac catcaataat catcgccagc
    29821 gtctcgctgc gcatggtgac aaaggcttcg gcgcgcgctt cacgcacggt ttccgctttg
    29881 gcggagacat cgaccatgtg cgcttcgcca gcggcgttga tatgggtcag ttgcgacata
    29941 cttatttctt caaatgtgga tggaaattac acggacgcgt acgggcatcc agctgcggcg
    30001 caatgatatt ttcccatgcg gtacggcacg ctttggtcga acccggcatg gcgaaaatca
    30061 gcgttttgtt agcgacgccc gctaccgcac gagattgcaa cgtggaagtg ccaatctctt
    30121 cgaacgacaa catccggaac acttcaccaa aaccttcaac ttcacggtcg aacaacggca
    30181 gcagcgcttc gggagcctga tctccttccg tcaggccagt accacccgta atcaacacca
    30241 cttgtacatc gtcgctggcg atccacgcag agacctgagc gcgaatagcg tagcggtttt
    30301 ctttcacaat ggctttatcg acaacgtgat ggcccgcttc ttgcgccgag tcgcgaagat
    30361 agtgaccgga ggtatcgtct tcttcaccgc gacgattaga aaccgtaaga atagcaatac
    30421 gggtcgggat aaattcagtg cttacctgac tcatctgatc tctccttttg acgttttagc
    30481 caccaatgta cgataagttt tgcgtaatac cggtgttatt ttgatgcagg aaatgggtct
    30541 gttttttctc ccgcagcgcc gctgaaatac gcgcttccag cgcctgttgc tgggtatcgt
    30601 tttccagcag atcgcgcagg ttaacgccgc cttcaccaaa caggcagaga tggagtttac
    30661 caatggagga aacgcgcagg cggttgcaag tggcgcagaa atctttttca tacggcatga
    30721 taaggccaat ctctccggcg taatccggat gacaaaagac ttgcgcggga ccgtcgctgc
    30781 gttgacgtaa ttggtggatc cagccgcgac gcagtaactc gtcacgcaga acctgaccag
    30841 agatgtgatg cttacggaag agctcgctgc cctcgcccgt ttccatcagt tcgatgaaac
    30901 gcagctggat gggacgatgc tggatccagt tcagaaaggt gtcgagctgg tgatgattca
    30961 catcacgcat cagcacggta ttgactttga ccttctcaaa accggcctca aatgcagcat
    31021 cgattcctgc catgacctga ttgaatttat cctgcccggt aatggcatga aactggcgag
    31081 cgtcaaggct atcaacgctg acgttgatgc cagtaagtcc agcatcgcgc cagttcgcca
    31141 catcgcgctc cagacggtaa ccattggtgg tgaccgctat ctggcgaata gcgtcgtttt
    31201 ctcgcacagc ggcgatgata tcggtaaagt cgcggcgtaa agatggctca ccacctgtca
    31261 gacggacttt ttcggtgccc agactggcga aggcgcgcgt aacccggcga atttcatcga
    31321 cggtcaggaa gcctttattg gtgacgccgc tcggcttgta accatccggc aggcagtagg
    31381 tgcaacgaaa gttacacaca tcagtaatcg acaggcgcaa gtagtaaaac ttacgcgcaa
    31441 atgcatcagt cagttgtgaa gccatgtaca cctttccaga tacgggaggc gaagtcattt
    31501 cttccttcgc cctggtggca atctttacga gcattgtcac ggccaaagca ccgtatcagt
    31561 tgacccaggt gcagaggcta gagtgtttag tggttaagcc gatactagcg tgtaaatgag
    31621 atttttacca tccacacttt cgctatgtaa tcatgtatat agcgtcatga tcgtgctatt
    31681 tcgctacaga ataagggaaa atggcggttt tactttgata tacatcatca gggaggcata
    31741 gcgtgcatcg tcctttagag gtagaagaaa atagtttgta tcctcaatat tggcaggtta
    31801 attgctgttt cctcgcaatt tgcgctactg tagcgcggat aatctgactc caggaaacta
    31861 tatgcgcaat cgtacgctgg ctgatcttga tcgtgtcgtt gctctcggcg gagggcatgg
    31921 actgggacgc gttctctcat cactttcgtc tttgggttct cgtttaacgg gtatcgtcac
    31981 caccaccgat aacggtggct cgacggggcg tattcgccgc tcagaaggcg gcattgcctg
    32041 gggcgatatg cgcaactgcc tcaatcagct gataactgaa cccagcgtcg cttccgcaat
    32101 gtttgaatat cgtttcggcg gtaatggcga actttccggg cacaaccttg gaaacctgat
    32161 gttaaaggca ctggatcacc ttagcgtgcg acctcttgaa gcgatcaatc tgattcgaaa
    32221 tctgctgaaa gtggacgcac atttgattcc gatgtcggag catcctgttg atctgatggc
    32281 gattgacgat caggggcatg aagtttacgg cgaggtcaat atcgaccagt taactgcgcc
    32341 gattcaagag ttattgttaa cgccgaatgt acccgcaacg cgtgaggcgg ttcacgctat
    32401 cagtgaagcg gatctcatca ttattgggcc tggcagtttt tacaccagcc tgatgccaat
    32461 tctgctgctg aaggaaatcg cacaggcatt acgccgcacg ccagcgccga tggtctatat
    32521 cggcaatctg gggcgtgagt tgagtttacc tgcggctaat ctgaagctgg aaagcaagct
    32581 ggcaattatg gagcagtatg ttggtaaaaa ggtaattgat gcggtcatcg tcgggccaaa
    32641 agtggatgtc tcggcggtga aagagcggat tgtgattcag gaagtgctgg aggccagcga
    32701 tattccgtat cgtcatgacc gccagttgtt gcatagcgcg ctggaaaagg cattacaggc
    32761 tttaggttaa cacgaagccg gaagaatatt ccggcttcgt catcttgtca cgacgcggca
    32821 ataaacagct cacgcaactg atgcaactgg tcacgaattt gcgccgcttc ttcgaactcc
    32881 agattctgcg cgtgttgcat catcaaccct tccagttcat ggatcttctg ctgtaacgct
    32941 ttaggcgaca tatccatcgg cacattatcc ggctcaacaa tcgggcgcga ttttcctctg
    33001 cccttcgctt tggttttggc aatgttctgc cccagcgcca ggatatcgac cactttcttg
    33061 ttcaagcctt gcggcgtaat gccgtgttcc tcgttgtact tctgctgttt ctcgcggcga
    33121 cgttcggttt cgccaatcgc tttcgccatt gatggggtga tcttatcgcc gtagagaatc
    33181 gctttaccgt taacgttacg tgccgcacga ccaatggtct ggatcaacga acgttcggaa
    33241 cgcaggaagc cttctttgtc agcgtcgagg atcgccacca gcgaaacctc cggcatatcc
    33301 agaccttcgc gcagtaagtt gatccctacc aatacgtcga actcacccag acgcaagtcg
    33361 cggataatct ccatacgttc gacggtatcg atatctgagt gaagataacg cacgcgctca
    33421 ccgtgttctt cgagatattc agtgagatct tccgccatcc gcttggtcag agttgtaacc
    33481 agtacgcgtt cgttaattgc cgctcgctga cgaatctccg atagaagatc atccacctgt
    33541 gtcgctaccg gacgcacttc aataatcggg tcgagtaagc ctgttggacg cacaacctga
    33601 tccaccacat cgccaccgga tttttccagc tcgtaattac ccggcgtcgc cgaaacatag
    33661 atggtttgcg gcgctaatgc ttcgaactct tcaaatttca gcgggcggtt atccagcgct
    33721 gatggcaagc ggaagccgta ctccaccagt gtctctttac gcgcccggtc accgcgatac
    33781 atgccgccaa tttgtggaat ggtgacgtga gattcatcga ccaccagcag cccatcagca
    33841 ggcaggtaat caaacagcgt cggcggtggc tcacccggtc cacgaccgga gaggaagcgc
    33901 gagtagttct caatccccga acagtagcct agctcgttca tcatctccag atcaaactgg
    33961 gtacgctggg tcagccgctg ctcttccagc agtttgttgt tttccaatag cactttacgt
    34021 ctggcggcca gctcttcttt gatctcctcc atcgcctgga cgatgcgctc gcgtggcgtg
    34081 acgtagtgcg ttttcgggta gatggtaaaa cgtggaatag tggaaacaat ctgcccggtc
    34141 agcgggtcaa ataacgacaa tcgttccacc tcctcgtcaa acagctccac gcgaagtgca
    34201 atgtcatccg attctgccgg gaagatatca atcacctcgc cacgaacacg gaaagtacca
    34261 cgctggaatg cttgatcatt acgggcatat tgcagctccg ccagtcggcg caggatcgcg
    34321 cgctgatcga taatcatacc gaccgtgaga tggagcatca tcttgagata taaatcagga
    34381 tcgcccagac cataaatcgc ggaaacagac gccaccacaa ccacatcacg tcgctccagc
    34441 atcgctttgg tggcggataa acgcatctgt tcgatatgtt cgtttaccga ggcatctttc
    34501 tcaataaagg tgtcggaact cggtacatag gcctccggct gatagtagtc gtagtaggag
    34561 acgaaatatt ccaccgcgtt ttctgggaag aattctttca tttcgccata cagctgggcc
    34621 gccagcgttt tgttgggcgc aagtaccatg gttgggcgct gaaggtcagc aatgacattg
    34681 gcaatggtga aggttttccc ggagccagtc acgccaagta acgtctggtg cgccaggcca
    34741 tcttccagcc cctcttcgag acgtcgaatc gcctccggct gatcgccaga aggtttaaaa
    34801 gcggaattca gtttgaacgg tttactcatg agtcgctacc tgaaggagtt gggcgggcag
    34861 gtatgtaatt ttactcgtcg tacttaatta tgccaacaaa ttatactgga taaaaaaaca
    34921 gttcatcacc ataatatttc tgttacagcg taaactccgc tgtcaatcat gaacaagatt
    34981 tactctgcgg cgagataaaa ctccggcctt accgggttat ccccaaagca acggcttttt
    35041 taacatttgt caagatgatt gatgacagtt ttatggcaag agatgcctgt tcagtgactg
    35101 ccattgcaat tatctaacct gttaaaaaat aaaagatatt tctttgagct gtctttaacg
    35161 ccaattcgcg tgcaagccgc gtattctctc gcttgcctcg tgttttctaa ctctaataca
    35221 catggttatc cacaggaata gtggataact gtctgcagcc cctatccccc gccgcctggg
    35281 caattcccac attcaccgca tgatgcggag gtaaaatttt tttcgtgatt tttttagaat
    35341 ttaattggtt aaattgcagt caatcggaga cacgatctcg ctcgcaattt aaccaattac
    35401 aggatgacta cattaaggca agattgatgt actttccggt tgccgcattt tctggatttt
    35461 ctgcaagcca gggaatttcg cccagcagcg gcgcgggaat catgcgggtg agcgtggtca
    35521 tatattcagc gtgacgtttt cccggaggcg tgacatcgtt cgccacccac cccgccagag
    35581 tcagtccggc gtgtagtatt gcctgcgcag tcaacatcgc gtgattaata cagccgagtt
    35641 tcacgcccac aaccagtatc actggcagtt gttcctgtgt tacccaatcc gcaaaagtga
    35701 aagtgtcaga aagcggcgta aaccagccgc cagcaccttc cactaacacc cagtcagcct
    35761 gttgttcaag cgcgcgtaat ccggcgctca ttaccaatgc ttctatcggc ctgccctctt
    35821 gcgcgctgat gatatgcggc gaggtgggtt ctgcgaaggt gtaaggattt accgttgcgt
    35881 aatccagctg caggctactg ttgcgctgta acgccagcgc gtcactatta cgtaagcctt
    35941 tcggggtctt ttcgctgcca gaggccaccg gtttgtaacc tgccgtccgg tagcctgctg
    36001 cctttgcggc ttgtaaaagc gcgcagctgg cgacagtttt ccccacttcg gtatccgttc
    36061 cggtgacaaa ataacattta ctcacgagca atcactccca aaaaaagatg atacgtcaga
    36121 ggatatcgcc cctgttgttg cggccaggcc agttgcaatc gctgcaactg cgaacgcgtt
    36181 aatattcgcg ggtcacgccc ttcatgaaga tgcgtggcac cgatgccttt cagcgaacgc
    36241 atggcactga gcgcatcatc aaaccacagc gtgatgggct gaatataatg ttgataatgc
    36301 acggcgttta gcgactgttc gatttcatct ggcggtaaaa agcgattagc atgcggacgc
    36361 tcgtccaccg cctgccacgc ctgatgcagt tcgggtaacg atccctgcac cagcgtggta
    36421 aacgcgacca cgcctccggg gcgcaccacc cgatacagct cgcggagtgc cgtggataaa
    36481 ttaccgcacc actgcaccgc gagattgctc catgcaagat cgaacgtcgc agtcgctaac
    36541 ggcagggatt cgatatctcc cgccagataa tggtctgcgg catccttctg gcgtgcctga
    36601 acaagcattg gcggagagag atctaacgca gtcacctgcg cgtgacgctc tcgccagcgg
    36661 cggctcatcc agcctggtcc acaacccgca tccagtacgc gggtgtattt acgctgtggg
    36721 agcattgcca gtaaggtgtc agcactctgg cgctgtagat cggcgtgttg ctcatagtgt
    36781 gcggctgccc gtccaaatgc cgcagcaatg gcttgtttat taaccgttgc catgcagcac
    36841 ctccagcaga cggtcgatat cctgcatttc atgcgctgcg gttagcgtta agcgcagtcg
    36901 cgcagtacca gcgggtacgg ttggcgggcg aattgccgtg acccaacagc cttgctggcg
    36961 cagtttttct gccagttgta acgcacggct gttatcaccg acgatcaatg gctggatggc
    37021 gctccatgaa tcagcaagcg taaacggcaa atcctgcact ccggcacgaa aacgcgttat
    37081 gagtgccgcc agtttttcgc gccgtgcatc cccctcatca ctgcgaatga ctgccagcga
    37141 cgcacgtaat gcctgcgcct gagcgggcgg catactggtg ctgtagataa gatggcgagc
    37201 gaattgcagc agataatccg ccaccgtatt ggagcaaagc accgctgccc cgctgacgcc
    37261 aaatcctttg ccaaacgtca ccaccagcaa ttctggtttt accttttgca gccagcagct
    37321 gccacgcccc tgctccccga taacgcccgt gccgtgggcg tcatcgacca tcaaccagcc
    37381 atcgtgctgt tgcgttacct gctggatttc ctccagtggc gcactatcgc cgtccatgct
    37441 gaacacgcct tctgtcacta ccagttgctg ccccggacag ggggaagcaa gcagtcgcgc
    37501 cagatgagtg acatcgttat gagcaaaacg gcgaagcggc gacgggctta aacttgcagc
    37561 ctccagcaat gaggcatggc taagccggtc ggcaacaata cggtcctctt tcgccatcat
    37621 cgcggcaatg actgcctgat tagcagcaaa accagagata aacagcagtg cccgcgaata
    37681 gcccagccac tcggccagtt cttcttccag cgcctgatgc gccacgctat aaccgctgac
    37741 gtgaccggag ccgccgctac cgatgccaaa ttgctccgca ccctgcttcc aggcacggat
    37801 aatttgcgga tgatggctta aacctaaata atcgttactg gaaaagttca gatactggcg
    37861 atcatccacc accagccagc gtccggctcc ttgcgccacc ggataacggc gacgcagggc
    37921 atcggcagca cgccgcgcat cgagcgccgc gttgattttc tcctgccagc tcatagtgct
    37981 gccgcgttgt aatattcgtc agtgtccggg gtcatcagcg cctgctccag acgctgctgt
    38041 tgttcgttat cgcccgccag cacggcagtt tgctgcggat ttagccccag tttgcggaac
    38101 agttgcaggt ctttatcttc ttccggattc ggcgtggtca gcagtttgca accgtagaaa
    38161 atcgagtttg cgccagccat aaagcacatc gcctgagtct gttcgttcat ctgctcgcgt
    38221 ccggcagaaa ggcgtacgta agaggtcggc atcatgatcc gcgcaactgc aatggtgcga
    38281 ataaaatcaa aggcatcgac atcatcgtta tccgccagcg gcgtgccttt caccttcacc
    38341 agcatgttga ttggtacgct ttccggcggc gttggcaggt ttgccagttg cagcaataat
    38401 ccggcgcgat cttttactgt ttcgcctaag cccacaatgc cgcctgaaca gactttgatc
    38461 ccggcgtcgc gcactttttc cagcgtatcg aggcgttcct gataggtacg cgtggtgatg
    38521 atattgccgt aaaactccgg cgaggtgtcg aggttgtggt tgtagtaatc cagcccggca
    38581 ttcgccaggc gctgcgcctg agattcactc aacgtgccca gcgtcataca cgcctccagc
    38641 cccatcgctt ttaccccctg caccatttgt tccaggtacg gcatatcgcg ttcgtgggga
    38701 ttcttccacg ccgcgcccat acagaaacgc gtcgatcccg ccgctttcgc tttgcgcgcc
    38761 gactccagca cctgttcaac ttccatcaac cgctcggctt ccagcccggt tttgtagcgc
    38821 gagctttgcg ggcaatattt gcaatcttcc ggacaagctc cggtcttaat cgacagcaaa
    38881 gtgctgacct gcacctgacg aggatcgaaa tgctgacgat gcacctgctg cgcttcaaac
    38941 agcagatcca gcaacggttt ttcaaataat tctgtgactt gcgacaatgt ccagcgtggg
    39001 cggtgagcca tggggcttct ccaaaacgtg ttttttgttg ttaattcggt gtagactcgt
    39061 aaacctaaat cttttcaatt tggtttacaa gtcgattatg acaacggacg atcttgcctt
    39121 tgaccaacgc catatctggc acccatacac atccatgacc tccccgctgc cggtttatcc
    39181 ggtggcaagc gccgaaggtt gcgagctaat tttgtctgac ggcagacgcc tggttgacgg
    39241 tatgtcgtcc tggtgggcgg cgatccacgg ttacaatcac ccgcagctta atgcggcgat
    39301 gaagtcgcaa attgatgcta tgtcgcatgt gatgtttggc ggtatcaccc atgcgcccgc
    39361 cattgagctg tgccgcaaat tggtggcaat gacgccgcaa ccactggagt gcgtttttct
    39421 cgcggactcc ggctccgtag cggtagaagt ggcgatgaaa atggcgttgc agtactggca
    39481 ggccaaaggc gaagcgcgcc agcgttttct aaccttccgc aatggttatc atggcgatac
    39541 ctttggcgcg atgtcggtgt gcgatccgga caactcaatg cacaacctgt ggaaaggcta
    39601 tctgccagaa aacctgtttg ctcccgcccc gcaaagccgc atggatggcg aatgggatga
    39661 gcgcgatatg gtgggctttg cccgcctgat ggcggcgcat cgtcatgaaa tcgcggcggt
    39721 gatcattgaa ccgattgtcc agggcgcagg cgggatgcgc atgtaccatc cggaatggtt
    39781 aaaacgaatc cgcaaaatgt gcgatcgcga aggtatcttg ctgattgccg acgagatcgc
    39841 caccggattt ggtcgtaccg gcaaactgtt tgcctgtgaa catgcagaaa tcgcgccgga
    39901 tattttgtgt ctcggtaaag ccttaaccgg cggcacaatg accctttccg ccacgctcac
    39961 cacgcgcgag gttgcggaaa ccatcagtaa cggcgaagcc ggctgcttta tgcatgggcc
    40021 aacttttatg ggcaatccgc tggcctgcgc agcagcaaac gccagcctgg cgattctcga
    40081 atctggcgac tggcagcatc aggtggcggc tattgaagcg cagctacgcg agcaacttgc
    40141 ccccgcctgt gacgccgaaa tggttgccga tgtgcgcgta ctgggggcaa tcggcgtggt
    40201 cgaaacctct cgtccggtga atatggcagc gctgcaaaaa ttctttgtcg aacagggtgt
    40261 ctggatccgg ccttttggca aactgattta cctgatgccg ccctatatta ttctcccgca
    40321 acagttgcag cgtctgaccg cagcggttaa tcgtgcggtg caggatgaaa catttttttg
    40381 ccaataacgg gaagtcagcg tgagggtttc tggctacact ttctgcaaac aagaaaggag
    40441 ggctcatgaa actcatcagt aatgatttac gcgatggcga taagctgccg catcgtcatg
    40501 tctttaacgg catgggttac gatggcgata atatttcacc gcatctggcg tgggatgatg
    40561 ttcctgtggg aacgaaaagt tttgttgtca cctgctacga cccggatgcg ccaactggct
    40621 ccggctggtg gcactgggta gttgttaatt tacccgcgga tacccgcgta ttaccgcaag
    40681 ggtttggatc tggtctggta gcaatgccag acggcgtttt gcagacgcgt accgactttg
    40741 gtaaaaccgg atacgatggc gcagcgccgc cgaaaggcga aacccatcgc tacattttta
    40801 ccgttcacgc gctggatgta gaacgtattg atgtcgatga aggtgccagc ggcgcgatgg
    40861 tcgggtttaa cgttcatttt cactctctgg cgagtgcctc gattactgcg atgtttagtt
    40921 aatcactctg ccagatggcg caatgccatc tggtatcact taaaggtatt aaaaacaact
    40981 ttttgtcttt ttaccttccc gtttcgctca agttagtata aaaaagcagg cttcaacgga
    41041 ttcatttttc tatttcatag cccggagcaa cctgtgaaca cattttcagt ttcccgtctg
    41101 gcgctggcat tggcttttgg cgtgacgctg accgcctgta gctcaacacc gcccgatcaa
    41161 cgtccttctg atcaaaccgc gcctggtacc tcttctcgcc cgattctgtc ggcaaaagaa
    41221 gcgcagaatt tcgatgctca acactatttt gcatccctga caccaggtgc ggcagcgtgg
    41281 aatccttccc cgattaccct gcctgcgcaa cctgactttg ttgtcggccc ggcgggtact
    41341 caaggtgtaa cgcataccac gattcaggcg gcggtagatg cggcaattat caagcgtacc
    41401 aacaagcgcc agtatattgc cgtgatgcct ggtgagtatc agggaacggt gtatgtccct
    41461 gccgctccgg gtggaattac tctgtacggt acaggtgaaa aaccgattga tgtgaagatt
    41521 gggctttccc ttgatggtgg catgagccct gccgactggc gtcacgacgt caacccgcgc
    41581 ggcaaatata tgccaggtaa accggcgtgg tatatgtacg atagctgcca gagtaaacgc
    41641 agcgacagta tcggtgttct ctgctctgcg gtcttctggt cacaaaacaa tggcctgcaa
    41701 ctgcaaaacc tgaccatcga aaacacgctg ggcgatagcg tagatgcggg taaccatccg
    41761 gcggtggcac tgcgtactga tggcgacaaa gtgcagatca ataacgtcaa cattctcggt
    41821 cgtcagaaca ccttctttgt caccaacagc ggtgtgcaga accgtctgga aacgaatcgc
    41881 cagccgcgta cgctggtgac caacagctat attgaagggg atgtggatat cgtttctggt
    41941 cgcggcgcag tggtgttcga taacaccgaa ttccgcgtgg tgaactcccg tacccagcaa
    42001 gaagcgtatg tgtttgcacc ggctacgctg tccaacattt actacggttt cctcgccgta
    42061 aacagccgtt tcaatgcttc cggtgatggc gtggcgcaac tgggccgctc gctggatgtt
    42121 gatgccaata ccaacggtca ggtagtgatc cgtgatagcg ccatcaacga aggttttaac
    42181 acagccaaac cgtgggctga tgcggtgatc tctaatcgcc cgtttgcggg taacaccggc
    42241 agcgttgatg ataacgacga agtacaacgc aatctgaatg acactaacta caaccgcatg
    42301 tgggaataca ataaccgcgg cgtgggtagc aaagtggttg cagaggcgaa gaagtaggag
    42361 ctgttaacta tgtgccggat gcggcgtaaa cgccttatcc ggcctacagt tcgatacgat
    42421 ttgtcggtcg gataagatgc gccagcatcg catccgacaa taagtgccgg atgcgaccta
    42481 cattcacatg gcgcttttta catctgacgg tttttattga agttaatcaa actacccgcc
    42541 ttgataatct cgcgttcttc ggcagtcaga ctttccatat agagcgtgat ttccgttacc
    42601 ggtgcatctt catggatcac ataaccttta aacgtcgttc caggattatc cagcgccgct
    42661 ttaatgccag ggatgtaaat gtaatccccc acttcaaagg ttggcgcttc cgccatctgc
    42721 agcggtaaca tcccccagtt gatgacgtta gaacgatagc gtttagtcgc gtactcctcg
    42781 gcaatattcg ccagaccgcc aatcacacgc tgacaactcg ccgcctgttc acgcgcagaa
    42841 ccatcgcctg gtttcaccgc atagaccatg ctgccaattt cagtttgcag cggatcaaca
    42901 tgttcctgac cagcaatctg cttaatgcgc gcaaacacct ctgccatctc gctgacattc
    42961 cccgccagac gctgattttc cagctcagca gtcgctttac ttctgccaac ataacctgga
    43021 tcgcggcgtg acagggtaaa ctccgccaga ccaatcggat ttgaacgata agaagaggtt
    43081 tcaccggaag gaatcagttc gtcggtggtg gtcacttcgt cgaggatctt cgagcacact
    43141 ttgaggacga tattgtcagt cagcgcaccc aattccggcc agtctttaat gttcggtccg
    43201 taaatcagcg gttgctgggt cgcccctttc acaaagcctt gatagacgcg atttttatac
    43261 ggcgttacat cgaaggcgta ctccggcacg ttgtcccagc aatcgagttc gctggcagag
    43321 gttaaatagc caccgtttgc cgcagtcgca gcgatagaac gagcgtccat caacgccacc
    43381 gctgacatct gcccattagc tggcttagag ccttcgcggt tcgggaagtt acgcgtggtg
    43441 tggcgaatac tcaaaccgtt gttgattggc gtatcgcccg cgccaaagca tgggccgcag
    43501 aacgcggttc tgatgattgc gcctgcgcca atcaaatctg cgaccacacc ttttttggcg
    43561 agatccataa acaccggctg tgatgacggg taaaccgcta acgagaaggt gtcattgccg
    43621 caggattgac cgcgcagcgc attcgccgcc gcgatgacgt tttcatagtt accgccagaa
    43681 cagcccgcga taatcccctg ctgcactttc aggcgaccat tttccacttt atccagcagc
    43741 gagagtttgg ctttaccgtg cgccacgcgt tcggactcaa tttcaatctc acgcagaatg
    43801 tcggtcaggt tctggttcag cgtgtcgatt tcatacacgt tgctcgggtg gaatggcagc
    43861 gcaatcattg gtttgatggc gcttaaatca acgctgatgc agccatcgta gtacgccatt
    43921 ggttgagggt taagttggca gtaatcctgg ccgcgaccgt gcagcgccag ccagttatgg
    43981 acttcttcat cggtttgcca gacagaactt aaacaggtcg tttcagtggt catcacgtca
    44041 acgctgttac ggaaatcggt agagagcgct gcaacaccgg gacctacgaa ctccatcact
    44101 ttgtttttga cgtaaccgtt tttgaacacg gcaccgatga tagccagcgc cacatcctgc
    44161 ggccccacat acggcgcagg ttttccggtc agatgcaccg caaccacgcc cggatagtcg
    44221 atatcccagg tgtcattaag cagttgtttt accagctcgc cgccgccctc accgactgcc
    44281 attgtcccta atgcgccgta acgggtgtgg ctgtctgatc cgaggatcat tttgccgccg
    44341 ccagccatca tttcacgcat atattgatgg atgaccgcaa tatgcggtgg cacaaaaata
    44401 ccgccataac gctgggccgc cgataaacca aaaacatggt catcaccgtt aatggtgccg
    44461 ccgacggcgc agagtgagtt atggcagttg gtcagcacat acggcagcgg gaaacgttcc
    44521 ataccggacg ctttagcggt ctgtacaata ccaacaaagg taatatcgtg agaggctaat
    44581 gaatcaaact taattttaag tttatccata tttccggacg tattatgaga agagagaata
    44641 gaccaggcaa tagtgccttt tttggcttct tcttttttaa tttcgccggt gaaatgttct
    44701 tcggcaatta tttcgttatt actggcgaga aacacgcctt tttcagataa cttgatcatc
    44761 aaatgctcca gatatctgcg caccggaaag tgcgcagaaa gataataaat ggatatactc
    44821 taaataattc gagttgcagg aaggcgacaa gcgagtgaat ccccagtcac ttacataagt
    44881 aagtgactgg ggtgagcgaa cgcagacgca gcacatgcaa cttgaagtat gacgagtata
    44941 tttacagcat gttccagccg atcagcatat tccaccacca cacgccgagg gtgatatgca
    45001 ccaggaaggt taatatcgtc agtaccgcac cgaccaacca ccaggattta atatcgttgt
    45061 aacccacgcc aaagatgacc ggacctgccg cgccgccata gtgagtaacc atgccgccat
    45121 aggagttaga gaacaacagt gccagcgcgg ttaacattaa cggtgcgccg gagacattcg
    45181 ccagcatggc aaataccggt aacatggcaa cgatataggc actaccagaa gcgaagaaat
    45241 aacgcacgat gatgctgagg aaaataataa cgaagaaagc aacgttcccg tgaccatcaa
    45301 atgccaggtt atttttaaag acttcagcta accattcgaa gaatttaact ttcgataata
    45361 aggagcttaa gccgataata ccgccgtacc agattaaggt attccagccg cctttatttt
    45421 taaccacgtc ttcccaggta acgataccca gcagcagcat agttgccata acaacgattg
    45481 ccacggtgga ttcatcaacc cccagagact tactgaaaat ccagcccagc agcgccagca
    45541 caaagacacc gagcagcatt ttttcgcgga ttttcatcgg tcccagttcg gcaaggcccg
    45601 ctttagcgat ggttttgtta tccaccttct taatttctgg tggatacatg gtgtaaatca
    45661 ccagcggggt gaccagcagc ataatgatgc ccggcaatcc ggcggctaac gcccatccac
    45721 cccagctaat ttgcaggtgc agaatgtcgt tgatcatttt cagcgccaga atgttccccg
    45781 ccattgcggt aaagaacata tagctggtgg ttttggtgac catgtaaatg gacatcatca
    45841 ggtaatgtcc aacacgacgc ggactttttt ccggttctga tcccaaagcc actgccacgc
    45901 tgttgatgat cggtaacacg atgccgcccg cacgcgcggt gttagacggt gttgccggag
    45961 ccagtaccag atcgagaaat accgtaacgt aacccagacc cagggtagtg ctaccaattt
    46021 taccaatcag cagataggca atacgtttac ctaagcctgt ggttacaaac gcggcgctta
    46081 aagtaaacgc agaaaacacc agccaggtgg taccggaaga gtaaccgctt aatacagcgg
    46141 tggttttaaa ttccccacct gataagttac ccaccactac catcgatgcg gcgacggcaa
    46201 ttaacagtac gacaggttcc gggaaaggct tgataaccag ccccacaatg gccgccaggt
    46261 aaataccaaa aagcacccac gccagttcgc ttaatcctgc cggagctggc ataaagccaa
    46321 taatacatgg gattgctaat atcagaatta gcttccataa cgatttctta ttcatttaat
    46381 atcctgttct ttctgtatga ctcatacaga attcctttat tgattgtcat tatcacgaca
    46441 acaaaatttt tcagggaaga taaacttcac cggaaaatat ttttctggtc gtccgaataa
    46501 cagatgcgcg taacgtcgtg gcatcctgac cttcattact taaatgaacg tcgagcgcac
    46561 cactggggtg ttcaatattg atattgccgt atcctacaga agggacgatt tgtcgggtga
    46621 cggtaccttc caatgcacaa ctactggaaa tagcaatagc accggttatc gccaaagcgc
    46681 gatggcaaga atgcggcata aaataacgca cattaattgc cccgcctttc tgcgctggag
    46741 aaataagtac aggtttaggg ataaccatat tactgacatc gcctaaaccc attgctttac
    46801 ccgcttgtag acggatagat tcaatgcggg ctaataatgc tttgtcggca tccagctctg
    46861 ccggtaattc atagcctgtt tttcccagat attcagcagg aataatgaca actggcatcg
    46921 ccatatcgat acaggtcacc gggacatcgt caaaataatc aatctgatta tccgtcggga
    46981 agacttttcc ggttttcgtt ccggcggcat tcaggaaagt gagcgcaacc ggtgcggcag
    47041 tacccggtac gccgtcaatt ctggcgctac cctcgtactc gacaacacca tttggcgttt
    47101 gcacatcagc ttcgatgaac gtacccgtat tgacgttgcg gatacgtacg cgggtaactg
    47161 gcgaagtcgc tgcaatcaaa ccattttcaa tggcgaatgc cccaacgcca gacagcatat
    47221 tgccgcagtt aggcgtggta tcgacacgtt gctcatggac gataacttga gcaaacagat
    47281 aatcgacatc tgcacgcgga tcgctggagc ggctaataat ggcgacttta ctggtcagcg
    47341 gattaccgcc gccaataccg tcaatttcca gatcgttacc ggaacccata attgccatca
    47401 atattttatc gcgctgcgtt tgatcttcgg gtagatgttc cgctaacagg aacgcgcccc
    47461 tcgaggttcc acctcgcatc atcacgcagg gtattttttt cataataatg ccctcaattt
    47521 aaaaacataa cttattgcga tatggttaca ttaagggcaa agcatctcta atgactttag
    47581 ctcaacgatt aataacattt tttcattaat ttaagttggc taaatgcagt taaaattttt
    47641 aactgccagt cacccaaaat cgtcgcttcc attttccgga gtaataatga agcatgaatt
    47701 atcaagtatg aaggcatttg tcatactggc agagtccagt tcatttaaca atgctgctaa
    47761 attactcaat attacgcaac ctgcattaac gcgaagaata aaaaagatgg aggaagattt
    47821 acacattcaa ctatttgagc gtacaactcg caaggttacg ttaacaaaag caggaaaaag
    47881 gttgctcccg gaggcgcggg aattaataaa aaaattcgat gaaacgcttt ttagtattcg
    47941 cgacatgaat gcttatcatc gaggtatggt gacgttagcg tgtattccga ccgcggtatt
    48001 ttatttttta ccattggcaa tcggtaaatt taatgagctg tatcccaata ttaaagtgcg
    48061 gattctggaa caaggcacga ataattgcat ggaatcggtg ctgtgtaacg aatcagactt
    48121 tggcataaac atgaacaacg tcacaaattc atccattgat tttaccccac tggtcaacga
    48181 gccgttcgtg ctggcctgtc ggcgtgacca tccattggcc aaaaagcagc ttgtagaatg
    48241 gcaggagtta gtgggttaca aaatgattgg cgtacgctcc tccagcggca accgactgtt
    48301 gatagaacaa cagctagccg acaagccctg gaagctggac tggttttacg aagtgcgtca
    48361 tctttcgacg tcattagggc tggtggaggc gggactgggg atttcggcgc ttcctggtct
    48421 ggcaatgccc catgcgccct attcttcgat tattggtatc ccactggtgg aacccgttat
    48481 acgtcggaca ttggggatta ttcgccgcaa agatgccgtg ctttctccgg cagctgaacg
    48541 cttttttgcc ttgctgatta atttgtggac tgacgataaa gacaatttgt ggaccaatat
    48601 cgtcgaacgc cagagacatg cgttacagga gataggttaa tacaccggcg caggagagac
    48661 tgcgccggtt aaatcagcgg ttagtgcgcg ttgaccacta cccacattgg cccctgccca
    48721 accgcatagc ggcctttttc atgcagtagc ccctgctcgc caacaatttc gtataccgag
    48781 atgtggtgag atttttgccc ggcggcaatc agatacttgc cgctgtgatc aacattgaag
    48841 ccgcgcggct gggtttccgt tggctggaag ccttctttac tcaacacgct gccatcttcc
    48901 gaaacgctga aaacggtaat cagactggcg gtacggtcgc aggcgtataa atgacgacca
    48961 tccggggtga tatgaatatc agccgcccaa cgggtgtcgg agaagttttc cggcatcata
    49021 tccagcgtct ggacacattc gatattgccg tgcggatctt tcagttccca gacatccact
    49081 gagctgttta actcattgac gcaatacgca tattgttcgt ttggatggaa taccatatga
    49141 cgcgggccgg ccccttcaac ggtagtcact tccgcagggt cctgcgccac cagatgacca
    49201 tcatcgctga ccgtaaacag gcaaatgcga tcctgcttta atgccggaac ccacaacgta
    49261 cggttgtccg gtgagatatt ggcggaatgg caaccgtcca gcccctcgac cacatcgacg
    49321 acgcccactg gcaggccatc ttccagacgc gttacgctca cgttacccgc attgtaagaa
    49381 ccgacaaaga caaactgccc ctggtgatcg gtggaaatat gcgtcgggct acccggcagc
    49441 gcagactctg cagcaaaggt cagcgcgcca tcatccggtg caatacgata cgccagaaca
    49501 cgaaactccg gacggacacc aacgtagagg taacgtttgt ccgggctgac caccatcggc
    49561 tgcacctgcc ccggcacatc gacaacctgt gtcagcgtca gtgcgccttc atgattcagg
    49621 ttccagacgt gaatttgctg gctctcaggg ctggcgatat aaactgtttg cttcatgaat
    49681 gctcctttgc atttagcaac tgactgtaac agctaaaatt agtcgctttt ggcggtgaat
    49741 gctgaattaa aacgcagaat tttgtccgat agtggtatcg gtgtaccatt cgcgcagacg
    49801 aaaattctta accttaatct ggaatacgcc atgaccacac gcgtgattgc tctcgactta
    49861 gacggcacct tattgacccc gaaaaagacc ctgcttccat catcgataga agccctggcc
    49921 cgcgctcgcg aagcaggcta tcgattaatc atcgtcacag gtcgccatca cgtcgctatt
    49981 catccttttt atcaggcgct ggcgctggat acacctgcta tttgctgtaa tggcacctat
    50041 ttgtatgatt atcatgcaaa aaccgtgctg gaagcggacc caatgcccgt taataaagcc
    50101 ctgcaactca ttgagatgct gaatgaacac cacattcacg gtctgatgta tgtggatgat
    50161 gcgatggtct atgagcaccc gaccggacat gtcattcgca cgtctaactg ggcgcaaacc
    50221 ctgccgccgg aacagcgtcc gactttcaca caagtcgctt ctctggctga aacggcgcaa
    50281 caagttaacg ccgtatggaa gttcgccctg acgcacgatg acctgccgca attgcagcat
    50341 tttggtaagc atgtcgaaca tgaactggga ctggagtgtg aatggtcctg gcacgatcag
    50401 gttgatattg cacgcggcgg caacagcaaa ggtaaacgtt tgacgaaatg ggttgaggcg
    50461 caaggctggt cgatggaaaa cgtcgtggcg ttcggcgata acttcaatga tattagtatg
    50521 ctggaagccg ctggtacagg cgtggcgatg ggcaacgccg atgacgcagt aaaagcgcgc
    50581 gccaacattg tgattggtga taacaccacc gacagcattg cccagttcat ttatagccac
    50641 ctgatttaat caggcggtta tcgacacact tttaatttgc gcatacagcc acaggccagg
    50701 tttgatcgcc agttcatccc tggcccacgg gctgatacgc gcccacagcg ttttacagcc
    50761 gacttccagc tccacttcca cctggccgtt gtcgtcataa ctattaacaa cttttgcccg
    50821 caatacgtta cgaatgctgg tttgctgcgg cggttgtaaa accagtgaga catcggaagc
    50881 ctgaatgcgg atgcgtagcg cagcttgcag cggttcgtcc agcttattga cccacaaatg
    50941 ctgatcgccc agcgccagcg cggtcatcgc gtaatgcgga tgatgctcaa gtactgtcac
    51001 tttcagaatg ctactttgtt gctctttcgg tagccacgga ttcatcacgc tactacccca
    51061 gacttcttcc agcgcgccaa aggctttcac ctgaccgttt tccagtacca tcactctgtc
    51121 tgccagatgg aggatctcat ccagcgaatg gctgacatac aacatcggaa tgttgatttc
    51181 ccgcgtcaga cgttgcagat aaggcaacag ttcgcgttta cgcggaatat ccagtgatgc
    51241 cagcggttca tccagcaaca gcaattccgg tgctgtcagc aaagcccgac caatcgccac
    51301 gcgctgtttt tcgcctccgg acaggctgcc tggtaaacga tcaagcaacg gttcaatgcc
    51361 taaaagcgcc accagcttat cgaactgatt gaccatgctt ttcgccatgc cgtagcgcaa
    51421 attgccacgc actttataat gcggaaacag ccgcgcatcc tgaaacacat agcctacgcg
    51481 acgcttttct ggcgtcaggc agataccttt atcggcgtca tttagtaccc gaccattgag
    51541 gacaatccgc cctttttgcg gacgtgtcag cccactgatg gcgttaatca gcgaggtttt
    51601 tccggcacca gagacaccaa aaatagcggt gatgccattg gcgggcagcg tttcattaat
    51661 cgtcaggcaa tggttgccca acgtctggga aaaattcagt tccagcatga ttagcgcccc
    51721 gcccgctcac ggctgattct ggccagccat tctgaaatca acagggagat catcgccagc
    51781 gcaatagaaa taatacacag tctcgccgcg ccactttccc cgccaggggt ctggatcagg
    51841 gtatacatgg cagaaggaat ggtccgcgtt tcaccaggaa tgttcgacac aaaggtgatg
    51901 gttgcgccaa attcaccgag cgaacgagcg aatgccagta ccgtaccaac aataattccc
    51961 ggtaaggtca gcggtaacgt gatagtaaag aaaacgcgcc agcgcccggc ccccagtgtt
    52021 cttgcggcct gctccagttt gatatcaaca ccttccagcg ccagacgaat cgcccgcacc
    52081 atcagcggaa aagacatgac agcggcagcg agaaccgcac cacgccagct aaacgcgaaa
    52141 gaaagaccaa accagtcata cagacgttca ccgataaatc cgcgccgtcc catcgaaact
    52201 aataataggt aaccgacgac cacgggcggt aacaccagcg gtagatgcag tacgctgtcg
    52261 agcagagctt tgcccggaaa cgtgcaacgt accagtaacc aggcaaaaaa gatcccaaac
    52321 ggcaggctaa acagcacagc cagggaagaa actttcaggc ttaataaaac tgcctgccat
    52381 tctggatcgg tcagtatcat tacttggttg taaatccgta acgtttaaag atttccgcag
    52441 cctgcggccc cttcagataa tcataaaatg ctttcactgt cgcattgtta tgcccttcca
    52501 caacagcaac cggatattcc acttttttat gtgaatcttc cgggaaggtg gcaaccactt
    52561 ttaccccttt gctggcaact gcgtcagaac cgtaaacaat acccagcggc gcttcattgc
    52621 gttcgaccaa cgccagcgcg ccacgaacat cttccgccgg agccagtttc ggggaaagcg
    52681 tatcccatgc gcccagtttt tgcagtgctt ctttcgcata aatgccagca gggacatgtt
    52741 ccggatcacc aaccgcgagg cgaccgccat tcagcagcga agtccagttg gttttgctgt
    52801 cgatggtgaa atctttctgc tcgctggctt tcggtgctac aacgaccagg ctattgccga
    52861 gcagtgtctg gcgcgaagcc gtatcgatcg cttttttatc aaccgcataa tccatccatt
    52921 tctgatcggc agaaataaac agatccgcag gcgcacccgc ttcaatctga cgggccaaag
    52981 tagatgacga agcgaaagaa gaaaccacat ccacgccttt ctctttttta tactgcgtag
    53041 caatgtcctg cattgcgtta gtcagtgatg cggcggcgaa caccgtgatt ttcccttcat
    53101 ctgccagtgc attgccagca acagcgaaag agagtgccgc cccggtaaac aagttcaacc
    53161 atttacgagc cattggtaac cccttaatct aacgttatgt aggcgtcaat ataacggcaa
    53221 gttcggaatt ttcccagcag ttattgctaa cctttgtgag gtagatgaga aaaaatatcg
    53281 gcagaaaaag caggaagttg agaaaaagaa aatgcccgac taagcgggca ttcagggaat
    53341 caatgatttt gtccgggctg gtctttttta ccaacaccag aaaagatgtt gaatacttca
    53401 ccaagaccgt aaatcagacc caggatgatg gccatcacga caggtaccat gattacggcg
    53461 aataccagac tttttaataa ctctaacatg gtcaactcca gatatagtca tgagactatt
    53521 ctaaccgcta agcacagaaa agcactcccc ttttgtgcgg tcagctttgc gtggcgttcg
    53581 ttttccgtca caataagact tttgccagga cattgttatg caggccgaaa tccttctcac
    53641 ccttaagctc caacaaaaat tattcgccga cccgcgccgc atttcgctac taaaacacat
    53701 tgcgctttcc ggttccatta gccagggagc gaaagatgcc ggtatcagct ataaaagcgc
    53761 ctgggatgcc attaacgaga tgaatcagtt aagtgagcat attctggttg agcgcgcaac
    53821 aggcggtaaa ggtggaggcg gcgcagtact gacccgctat ggtcagcgac tgattcaact
    53881 ctatgactta ctggcgcaaa tccagcaaaa agcctttgat gtgttaagtg acgatgacgc
    53941 cctgccgctg aacagcctgc tggccgcgat ctcacgtttt tcactgcaaa ccagcgcccg
    54001 taaccagtgg ttcggtacca tcaccgctcg cgatcatgat gacgttcaac agcatgttga
    54061 tgtcttactg gctgatggaa aaacacgcct gaaagtcgca attaccgcac aaagcggcgc
    54121 gcgtctgggg ctggatgaag gcaaagaagt gttgatattg ctaaaagcgc cgtgggtagg
    54181 tattactcag gacgaggcgg tcgcgcaaaa cgctgacaac caattaccgg gtattattag
    54241 tcatattgag cgcggcgcag agcagtgcga agtattaatg gcgctacccg acgggcaaac
    54301 actgtgcgcc acagtgccgg taaatgaagc gacttctctt cagcaagggc agaatgtcac
    54361 ggcctacttt aatgccgaca gcgtgattat cgccacgctg tgctaagcgt gttgacaatt
    54421 tgttatgaaa cacgtatccc tgtcagtaat cgctgcacaa aatgggatat aaaatgtcat
    54481 cgttgcaaat tttgcaaggc acgtttcgtc ttggcgacac aaaaacgctg caattgcctc
    54541 ggctaacgtt aaacgcgggt gatagttggg cgtttgtcgg ttcgaatgga agcgggaaat
    54601 cggcgctggc ccgcgcgctg tcgggggaac ttccgctttt gaaaggtgaa cggcaaagcc
    54661 agttttccca catcactcgt ctctccttcg agcaattgca aaagctcgtc agcgacgaat
    54721 ggcagcggaa taacaccgat atgcttagtc ctggcgaaga tgacaccggg cgtaccacgg
    54781 ctgagatcat tcaggatgaa gtaaaggata cttcgcgttg catgcaactg gcgcagcagt
    54841 tcggtattac cgccctcctc gaccgacgct ttaaatacct ttccactggc gagacgcgaa
    54901 aaaccctgct gtgtcaggcg ctgatgtcgg agcctgactt gttgatcctt gatgaaccgt
    54961 ttgatggcct ggatgttgcc tcacgtcagc atctggctga gctactcgcc tcgttacatc
    55021 agtccggtat tactctggta ctggtgctca atcgcttcga tgagatcccg gaatttgtcc
    55081 agtttgctgg cgtgctggcg gattgcacgt tagcggaaac tggcgctaaa gaagaactgc
    55141 tccaacaagc actcgttgcg caactggcgc atagcgaact gcttgaaggt gtgcaaatgc
    55201 cggagccgga tgaaccttca gcacgtcacg ccttacccgc caacgaaccg cgcattgtgc
    55261 tgaacaatgg cgtggtttct tataacgaac gccccatcct taataacctt agctggcagg
    55321 tgaatccagg cgaacactgg caaattgtcg ggccaaatgg cgcgggaaaa tcgacgttat
    55381 taagcctgat tactggcgat catccgcaag gttacagcaa cgatttgacg cttttcggac
    55441 gacgtcgcgg cagcggcgaa accatctggg atatcaaaaa gcatatcggt tacgtcagca
    55501 gtagtttgca tctggattac cgggtcagca ctactgtgcg taatgtgatt ctttctggct
    55561 attttgattc gattggcatt tatcaggccg tttcggatcg ccagcaaaaa ctggtgcagc
    55621 agtggctgga tattctcggc attgataaac gcacggctga cgctcctttc catagtcttt
    55681 cctggggaca gcagcgtctg gcgctgattg tccgcgcact ggtgaaacat ccgacgttgc
    55741 ttattctcga tgaaccacta caggggcttg atccgctcaa tcgccagctt atccgccgtt
    55801 ttgttgatgt gctgattagc gaaggtgaaa cgcaattgtt gtttgtttcg caccacgctg
    55861 aagatgcgcc tgcctgtatt acccatcgtc ttgagttcgt gccggacggt ggactctatc
    55921 gctatgtgct gacaaaaata aattgagtcg gtaatgctga ccgtgccgga ggcggcgtaa
    55981 acgtgttatc cggccaacgg tttgacgcat ccaggcatga aaccgcgtct tttttttcag
    56041 ataaaaagcg caatcattca taaagccgct gttttataat cacttaatcg cgcataaaaa
    56101 acggctaaat tcctgtgtaa acgattccac taatttattc catgtcacac ttttcgcatc
    56161 tttgttatgc tatggttatt tcataccata agcctaatgg agcgaattat gagagttctg
    56221 gttaccggtg gtagcggtta cattggaagt catacctgtg tgcaattact gcaaaacggt
    56281 catgatgtca tcattcttga taacctctgt aacagtaagc gcagcgtact gcctgttatc
    56341 gagcgtttag gcggcaaaca tccaacgttt gttgaaggcg atatccgtaa cgaagcgttg
    56401 atgaccgaga tcctgcacga tcacgctatc gacaccgtga tccacttcgc cgggctgaaa
    56461 gccgttggcg aatcggtaca aaaaccgctt gaatattacg acaacaatgt caacggtact
    56521 ctgcgcctga ttagcgccat gcgcgccgct aacgtcaaaa actttatctt tagctcctcc
    56581 gccaccgttt atggcgatca gcccaaaatt ccatatgttg aaagcttccc gaccggcaca
    56641 ccgcaaagtc cttacggcaa aagcaagctg atggtggaac agatccttac cgatctgcaa
    56701 aaagcccaac cggactggag cattgccctg ctgcgctact tcaacccggt tggcgcgcat
    56761 ccgtcgggtg atatgggcga agatccgcaa ggcattccga ataacctgat gccgtacatt
    56821 gcccaggttg ctgtaggccg tcgcgactca ctggcgattt ttggtaacga ttatccgacc
    56881 gaagacggca ctggcgtgcg cgattacatc cacgtaatgg atctggcaga tggtcacgtc
    56941 gtggcgatgg aaaaactggc gaacaagcca ggcgtacaca tctacaacct cggcgcaggc
    57001 gtaggcagca gcgtgctgga cgtagttaat gccttcagta aagcctgcgg caaaccggtt
    57061 aactatcatt ttgcaccacg tcgcgcgggc gaccttccgg cctactgggc ggacgccagc
    57121 aaagccgacc gtgaactgaa ctggcgcgta acgcgcacac tcgatgaaat ggcgcaggac
    57181 acctggcact ggcagtcacg ccatccacag ggatatcccg attaaggaac gaccatgacg
    57241 caatttaatc ccgttgatca tccacatcgc cgctacaacc cgctcaccgg gcaatggatt
    57301 ctggtttcac cgcaccgcgc taagcgcccc tggcaggggg cgcaggaaac gccagccaaa
    57361 caggtgttac ctgcgcacga tccagattgc ttcctctgcg caggtaatgt gcgggtgaca
    57421 ggcgataaaa accccgatta caccgggact tacgttttca ctaatgactt tgcggccttg
    57481 atgtctgaca cgccagatgc gccagaaagc aacgatcctt tgatgcgttg ccagagcgcg
    57541 cgcggtacca gccgggtgat ctgcttttca ccggatcaca gtaaaacgct gccagaactg
    57601 agcgttgcgg cattgacgga aatcgtcaaa acctggcagg agcaaaccgc agaactgggg
    57661 aaaacatacc cgtgggtgca ggtctttgaa aacaaaggcg cggcgatggg ctgctctaac
    57721 ccgcatccgc acggacagat ttgggcaaat agcttcctgc ctaacgaagc tgagcgcgaa
    57781 gaccgtctgc aaaaagaata tttcgccggg cagaaatcac caatgctggt ggattatgtt
    57841 cagcgcgagc tggcagacgg tagccgtacc gttgtcgaaa ccgaacactg gttagccgtc
    57901 gtgccttact gggctgcctg gccgttcgaa acgctactgc tgcccaaagc ccacgtttta
    57961 cggatcaccg atttgaccga cgcccagcgc agcgatttgg ctctggcgtt gaaaaagctg
    58021 accagtcgtt atgacaacct cttccagtgc tccttcccct actctatggg ctggcacggc
    58081 gcgccattta atggcgaaga gaatcaacac tggcagctgc acgcgcactt ttatccgcct
    58141 ctgttgcgct ctgccaccgt acgtaaattt atggttggtt atgaaatgct ggcagaaacc
    58201 cagcgagacc tgaccgcaga acaggccgca gagcgtttgc gcgcagtcag cgatatccat
    58261 tttcgcgaat ccggagtgta agaaatgagt ctgaaagaaa aaacacaatc tctgtttgcc
    58321 aacgcatttg gctaccctgc cactcacacc attcaggcgc ctggccgcgt gaatttgatt
    58381 ggtgaacaca ccgactacaa cgacggtttc gttctgccct gcgcgattga ttatcaaacc
    58441 gtgatcagct gtgcgccacg cgatgaccgt aaagttcgcg taatggcagc cgattatgaa
    58501 aatcagctcg acgagttttc cctcgatgcg cccattgtcg cgcatgaaaa ctatcaatgg
    58561 gcgaactacg ttcgtggcgt ggtgaaacat ctgcaactgc gtaacaacag cttcggcggt
    58621 gtggacatgg tgatcagcgg caatgtgccg cagggtgcag ggttaagttc ttccgcttca
    58681 ctggaagtcg cggtcggaac cgtattgcag cagctttatc atctgccgct ggacggcgca
    58741 caaatcgcgc ttaacggtca ggaagcagaa aaccagtttg taggctgtaa ctgtggaatc
    58801 atggatcaac tgatttccgc gctcggcaag aaagatcatg ccttgctgat cgattgccgc
    58861 tcactgggga ccaaagctgt ttccatgccg aaaggcgtgg ctgtcgtcat catcaacagt
    58921 aacttcaaac gtaccctggt tggcagcgaa tacaacaccc gtcgtgaaca gtgcgaaacc
    58981 ggtgcgcgtt tcttccagca gccagctctg cgcgatgtca ccattgaaga gttcaacgct
    59041 gttgcacatg aactggaccc gatcgtcgcg aaacgcgtgc gtcacatcct gactgaaaac
    59101 gcccgcaccg ttgaagctgc cagcgcgctg gagcaaggcg acctgaaacg tatgggcgag
    59161 ttgatggcgg agtctcatgc ctctatgcgc gatgatttcg aaatcaccgt accgcaaatt
    59221 gacactctgg tagaaatcgt caaagctgtg attggcgaca aaggtggcgt acgcatgacc
    59281 ggcggcggat ttggtggctg tatcgtcgcg ttgatcccgg aagaactggt gcctgccgta
    59341 cagcaagctg tcgctgaaca atatgaagca aaaacaggta ttaaagagac tttttacgtt
    59401 tgtaaaccat cacaaggagc aggacagtgc tgaacgaaac tcccgcactg gcacccgatg
    59461 gtcagccgta ccgactgtta actttgcgta acaacgcagg gatggtagtc acgctgatgg
    59521 actggggtgc gactttactt tccgcccgta ttccgctttc cgatggcagc gtccgcgagg
    59581 cgctgcttgg ctgcgccagc ccggaatgct atcaggatca ggccgcattt ctgggggcct
    59641 ctattggtcg ttatgccaac cgcatcgcca atagccgtta tacctttgac ggtgaaaccg
    59701 tgacgctttc accaagtcag ggcgtcaacc aattgcatgg cggcccggaa gggttcgaca
    59761 aacgtcgctg gcagattgtg aaccagaacg atcgtcaggt gctgtttgcc ctgagttcag
    59821 atgatggcga tcagggcttc ccgggtaatc tcggcgcgac ggtgcaatat cgtctgaccg
    59881 acgataaccg tatctccatt acttatcgcg ccacagttga taaaccttgc ccggtgaata
    59941 tgactaatca cgtctatttc aatcttgacg gcgagcagtc tgacgtgcgc aatcataagt
    60001 tgcagattct ggcggaagaa tatctgccgg ttgatgaagg cggcattccg cacgacggcc
    60061 tgaaatctgt cgccggaacc tcttttgatt tccgcaacgc caaaatcatc gccagtgagt
    60121 ttcttgccga cgacgatcag cgcaaagtga aaggttacga tcacgcgttc ttgttacagg
    60181 ccaaaggcga tggcaagaaa gtggcggcgc atgtctggtc agcagatgaa aaattgcagc
    60241 tgaaggtcta caccaccgct ccggctctgc aattctactc cggcaacttc ctcggcggca
    60301 caccgtcgcg gggaaccgaa ccttacgctg actggcaagg gctggctctg gaaagcgaat
    60361 ttctgccgga cagcccgaac caccctgaat ggccgcaacc ggactgcttc ctgcgtcctg
    60421 gcgaagagta ttccagcctg acggaatatc agtttattgc tcagtaatgt taagccctcg
    60481 tcatgagggc tttatcctca tattgttcaa atcaccagca aacaccgaca tatttgcaac
    60541 tcaatattca caacaacctt acactgcgac actattttcg ctatggttat gcgtaagcat
    60601 tgctgttgct tcgtcacggc aatataatga gaattattat cattaaaaga tgatttgagg
    60661 agtaagtata tggctgtaac taagctggtt ctggttcgtc atggcgaaag tcagtggaac
    60721 aaagaaaacc gtttcaccgg ttggtacgac gtggatctgt ctgagaaagg cgtaagcgaa
    60781 gcaaaagcag caggtaagct gctgaaagag gaaggttaca gctttgactt tgcttacacc
    60841 tctgtgctga aacgcgctat tcataccctg tggaatgtgc tggacgaact ggatcaggca
    60901 tggctgcccg ttgagaaatc ctggaaactg aacgaacgtc actacggtgc attgcagggt
    60961 ctgaacaaag cggaaaccgc tgaaaagtat ggcgacgagc aggtgaaaca gtggcgtcgt
    61021 ggttttgcgg tgactccgcc ggaactgact aaagatgatg agcgttatcc gggtcacgat
    61081 ccgcgttacg cgaaactgag cgagaaagag ctgccactga cggaaagcct ggcgctgacc
    61141 attgaccgcg tgatccctta ctggaatgaa accattctgc cgcgtatgaa gagcggtgag
    61201 cgcgtcatca tcgccgcaca cggtaactcg ttacgtgcgc tggtgaaata tctcgataac
    61261 atgagcgaag aagagattct tgagctgaat atcccgaccg gcgtgccgct ggtttatgag
    61321 tttgacgaga acttcaaacc gctgaaacgc tattatctgg gtaatgctga cgagatcgcg
    61381 gcgaaagcag cggcggttgc taaccagggt aaagcgaagt aaacgtcatt cgcttaaaaa
    61441 tgagaaagcc gactgcaaaa tgagtcggct tttttatttt tcgttgctac caatggagcg
    61501 cattgcctga tgcgacgctg cgcgttttat caggcctacg gtgattaatc ggatacgcca
    61561 ctctgacagc gcatccgaca attaaacttt acccgcgacg cgcttttact gcattcgcca
    61621 gttgacgtaa cagagcatcg gtatcatccc agccaatgca ggcatcggtg atgctcttac
    61681 cgtaggccag cggttccccg ctctcgaggc tctgattgcc ttccaccaga tggctttcca
    61741 ccatcacgcc aataatggcc ttttcgccac cggcaatctg ctggcaaacg tcagcacaaa
    61801 catccatctg ctttttgaat tgtttagacg agttagcatg gctgaaatcg atcatcacct
    61861 gtgctggcag gcctgctttg ttcagccctt ctttcacttc agcaacgtgc ttcgcgctgt
    61921 agttaggctc tttaccgccg cgcagaatga tatggcaatc gccgttaccg ctggtattca
    61981 caatcgccga atgaccccat ttggtcactg aaaggaagca gtgcggcgca ccggcggcat
    62041 taatggcatc gatagccact ttaatcgtac catcagtgcc atttttgaag cctaccgggc
    62101 aagaaagccc tgaagccagt tcgcggtgca cctgcgattc cgtagtacgt gcgccaattg
    62161 cgccccagct catcaggtca gcgagatatt gtggggtgat catatcgaga aactcacccg
    62221 ccgctggcag accgctgtcg ttaatatcaa gcaacaattt acgggcaata cgcagaccgt
    62281 cgttgatctg gaagctgtta tccatatgcg gatcgttaat cagccctttc cagcccaccg
    62341 tggtacgcgg cttttcaaaa tagacgcgca ttacgatttc cagctcatct ttcagctctt
    62401 cacgcagcgc cagcaagcga gtggcatact ctttagccgc gacaggatca tgaattgagc
    62461 atgggccaat caccaccaac aggcgatcat cattaccttt caggatctta tggatcgctt
    62521 ttcgggcatg ggcgaccgta ttcgcggcat tttcagtagc ggggaatttt tccagcaatg
    62581 cgacaggagg aagtaactct ttgatttctt tgatgcgtaa atcgtcgttc tgataattca
    62641 tgtctgttcc agtgttgcca tacttatctt agtgaatgca atacttccaa tctatatctt
    62701 ccgtcagaat gtgtaaacgg ggttttacac tatgaacgga ttaatcctgg aattagcaag
    62761 aaaaacgcca gattgtcgcg aaaaacgaga tctctcctac aatttctaac tgtaactcct
    62821 ttgtttgtta attatttcaa gattctctgc tgggtatctt tgcctggctg aaatcttaaa
    62881 ccattgcctt atattcacct gcaaatgcac tgttggaaga ggttatccga cataacgacc
    62941 ataacaggag catcctatga aaatgacaaa actggccaca ctatttttga ctgccactct
    63001 aagccttgcc agcggtgccg cactggctgc cgatagcgga gcgcaaacta ataacggcca
    63061 ggcaaacgcc gccgctgatg cgggccaggt agcccctgat gcccgtgaaa atgtcgcgcc
    63121 aaataacgtc gacaataacg gggtaaatac cggttctggc ggcacaatgc tgcatccgga
    63181 tggttcttca atgaacaatg acggcatgac caaagatgaa gagcacaaga acaccatgtg
    63241 caaagatggt cgctgcccgg atatcaataa aaaagtccaa accggtgatg gcatcaacaa
    63301 tgatgtcgat accaaaaccg acggtaccac gcagtaaccc tgcgaaatag ccaataatgg
    63361 gagagcgtag tctctccctt ttaatttttc ccttctaaaa gcagtatgat gtcataaagt
    63421 taagtgagaa taattaaggg atgactcgtc atggcgcact cacactcaca cacttcctca
    63481 cacctgccag aagataataa tgctcgtcgc ttgttgtatg ctttcggcgt gactgccggg
    63541 tttatgctcg tagaagtcat tggtggtttt ctttccggtt ctctggcatt gctggccgat
    63601 gcgggtcata tgttgaccga tactgccgcc ctgcttttcg ccctactcgc agtgcaattt
    63661 tcccgtcgtc ctcccaccat tcgccacact ttcggttggc taagattgac cacgctcgcg
    63721 gcgtttgtga atgccatcgc cctggtggtg attactattt tgattgtctg ggaggcgata
    63781 gaacgcttcc gcactccgcg tccggtcgag ggcggcatga tgatggcaat tgccgtggct
    63841 gggctgctgg caaatatact ttctttctgg ttacttcatc acggcagcga agagaaaaac
    63901 ctcaacgtgc gagcagcggc actgcatgtg ctcggggacc tgctgggttc ggttggggct
    63961 attattgccg cgttgattat tatctggacc ggctggacac ctgctgaccc cattctctca
    64021 atactggtgt cgcttctggt tctgcgtagc gcgtggcgac tgttgaaaga tagtgtgaat
    64081 gaattacttg aaggtgcacc ggtatcgctg gatatcgctg aactgaagcg tcgcttgtgc
    64141 cgggaaatcc cggaagtccg caatgtgcac catgtgcatg tatggatggt aggcgagaag
    64201 ccggtgatga cgctgcatgt gcaggtgatc ccgccacacg atcacgatgc cttgttggat
    64261 cagatccaac actacctgat ggatcactat cagattgagc acgccaccat tcagatggaa
    64321 tatcaacctt gtcatgggcc agactgccac ctgaatagag gggtgtctgg ccattcacat
    64381 catcatcatt aatgggacag cgcacgtgaa cctctttcgc gtgcgctttt gatccacatc
    64441 cggctgccgt tgagggcaat aaaggtcagg atgatgtact ccagagacat ggcgtaaacg
    64501 ccctgaagtg caaaaataac gacgctaatc acgttaataa tcacccacaa cagccagttt
    64561 tccacatact tacgtgtcat cagaatcatt gccacgatag ataacaccat catgcatgaa
    64621 tcccagaacg ggaaagcgtc cggctgtagt tcaggcatcg caacctgtaa tcctaatgct
    64681 tgcatgatca tgactgccac gcgggtcaaa aatgcaaaca caggattgat aaataccgtc
    64741 attagaccaa tcgaaacaac gcaaaccgcc agccagctta gcgccttcgg caatggcaac
    64801 cagcgaattt tcaactccgc ctcgttctga ctggtttgtc gcgaccacgc ataccagccg
    64861 taaatattcg cggcaaagaa aaacacctgt aataacaggc tggcatacag ctgaatctga
    64921 aagaaaataa tgccaaacaa ggtgacgttg atcaggccaa agaagtagtt actgatcttc
    64981 tccagactgg caaggccaat acacagcaac ccggcgatcg tgcctaccgc ttcgatccat
    65041 gagagatcat aaccgcctgc ccctattggt atatgtacca ggatattctg cacactaaaa
    65101 aaatccatcg ttcccccaaa gcgtaatgtg acgccttatt atcaattatc cacgtagtgt
    65161 agccgcaaaa tccagcatac gattgagcgg caccagcgcc ctctctcgca gcctttcatc
    65221 aacataaacc tcgtgattgc ttccttccag ttctaatgcc tctgcgatgg cctgaaggcc
    65281 attcatggcc atccacggac aatgcgcgca gctgcgacag gttgcgccct cacccgcggt
    65341 tggtgcttcc agtaactctt tatctggcac cgcctgctgc attttgtaga aaatgccccg
    65401 atcggttgcc acgataagcc gctgatgttg caatgttttc gcagcagcga tcagttgact
    65461 ggtggaaccg accgcatccg ccatctctac aatagcttgc ggtgattctg gatgcaccag
    65521 tatggcagca tccgggtatt cttcttgcaa gcgggttaac gcctgagtct taaactcatc
    65581 atgcacaatg caggcaccct gccagcataa aatgtctgcg cccgtctgtt tttgcacgta
    65641 acgccccaga tgtttgtcag gtgcccagat gattttttca cccaaactat ccagatgatc
    65701 aataagttcg acggcaatgc ttgaagttac cacccaatct gcgcgcgctt ttaccgcagc
    65761 agaagtgttg gcgtagacga cgacagtacg atcgggatgg gcatcgcaaa atgcgttaaa
    65821 ttcttcaaca gggcagccga gatccagtga acattcagcc tgaagtgtcg gcatcagaat
    65881 tgttttttcc ggactgagaa ttttggcggt ttctcccata aatctcaccc cagcgactag
    65941 caacgtagaa gcgggatgct ttgcaccgaa gcgcgccatt tccagagaat cagaaataca
    66001 gccaccggtt tcttctgcca gttgttgaat ttcgggatcg gtatagtagt gggcaaccat
    66061 caccgcatta cgttctttta gtagacgttt tatcttctcg cggtaattcg ctttttcatc
    66121 aatgcttaac ggcgtcggct tcggggggaa aggataaatc gccgtgtctg gatcaaacat
    66181 cacgctcatc ttaccatctc gttctacagg cttaacgtta aaaccgactt aagcgtgata
    66241 ttcgctatta tcggcgtaat ttgttttata tactaaacaa gatagtcgaa tggtggggaa
    66301 aagtcactcg aattacgtat gagatgccga atgccacact ttgcgtctta ttcctccgac
    66361 gtagagttgt ttacgcagca aacgcggagt atgtcatcag ggtcaagaat tgaaattgag
    66421 agatgcctga atagcaaaaa aacgccttta gggcgctttt ttgcattggt gggtcgtgca
    66481 ggattcgaac ctgcgaccaa ttgattaaaa gtcaactgct ctaccaactg agctaacgac
    66541 cccttgcggg attatgctgc tttaatcatt caggatggtg ggtcgtgcag gattcgaacc
    66601 tgcgaccaat tgattaaaag tcaactgctc taccaactga gctaacgacc catacgggtg
    66661 ttacctgaaa gatttctact cggaaccaat gtttaaaatt ggtgggtcgt gcaggattcg
    66721 aacctgcgac caattgatta aaagtcaact gctctaccaa ctgagctaac gacccgagtg
    66781 gtgggtgatg acgggatcga accgccgacc ccctccttgt aagggaggtg ctctcccagc
    66841 tgagctaatc acccgatact gcgctggata ctacaaacta cttccaccga acccaccgta
    66901 atcagtggtg ggtcgtgcag gattcgaacc tgcgaccaat tgattaaaag tcaactgctc
    66961 taccaactga gctaacgacc cggtggtggg tgatgacggg atcgaaccgc cgaccccctc
    67021 cttgtaaggg aggtgctctc ccagctgagc taatcacccg atactacgct ggatactaca
    67081 actaactatg ttagtggtgg gtcgtgcagg attcgaacct gcgaccaatt gattaaaagt
    67141 caactgctct accaactgag ctaacgaccc actttttcgt tgctttcggt ttgtttgata
    67201 tcccgtggca acggcggcat atattactga tttcagactt gagcgcaaca aaaatttcga
    67261 tgtagatcac tcaactgctt atgattcgca cgacacgacc agaaataatg cgacttctgg
    67321 tcgtgtgtta tgcattacat cgcgttcaga cgtttttgcg cctgtttagc gccatcagta
    67381 ccagggtatt tactgataac ctgctggtat acggctttcg cttttgcggt gtcacctttg
    67441 tcctgcatga tgacgccgac tttaaacatc gcatctgcag ccttcggtga cttcggatag
    67501 tttttcacta ccgaagcaaa ataatacgcc gcatcatctt ttttaccctt gttgtagttt
    67561 aactgaccca gccaataatt ggcgtttggc aggtaagttg aatcagggta atttttgatg
    67621 aaattctgaa atgccaccat tgcgtcatcc tggcgggatt tatcctgcac cagcgcaata
    67681 gctgcattgt aatccgtgtt tgcatcaccg cttttcaccg gcgcgccagc attcgaagta
    67741 ccagcatcag ctgtcggcgt cgttgatgcc accacaccgc tttgatcgcc gctggttgat
    67801 tgcgccgctg caccaccgct gctgaggctg tcgatctgca acaggatctg cttttgccgc
    67861 tccacgacct gattcagttg atactgattt tcctgaatct gaccacgcag ggaatcaata
    67921 tcggattgat tatcagagag ttgttgctgg agttgggtta aaagctggct gtgagcatta
    67981 gaaatacgct caagttgagt gacgcggtct tcgaccgagc ctgagccgac actactgatt
    68041 ggtgcctgag caaaagcggc ccagggggcc gctataccaa ccagtaacga cagactcaat
    68101 agttgatgtc tgaagttact gctcatgcaa ttctcttagt aaaccagtac cgcacgacgg
    68161 tttttggcat acgccgcttc gtcatgaccc agtactgcag gtttttcttt accgtaagaa
    68221 acgatggaga tctggtcagc agaaacgcct ttaccctgca gatacatctt aacagcgttc
    68281 gcacgacgtt cacccaggga gatgttgtat tccggagtac cacgttcgtc cgcgtgacct
    68341 tctacggtga ctttgtaaga cgggttgcta cgcaggaagt ttgcgtgtgc atccagcatt
    68401 tgagcgaagt cagaacggat atcgtacttg tccagatcga agtaaacgat gttgttctgc
    68461 tgcagctgtt gcatttgcag acgagcctgc tcttcggaag acatgttgcc gttgccgccg
    68521 ttcgcatcca taccagtgcc ggcacccagc atgccttcgc tgccgtcatt gctggcgttc
    68581 ttgttggaag aacatgccgc aattgccata acaggcagag caatcatcag ccctttcagc
    68641 actttgttca gttgcatttc aatgattcct ttactattca attaattatt atcacagata
    68701 cggcgaccag gcagggaatt tgacctgtcc atcagttgcc ggaagacgcg ctttgaaacg
    68761 cccatctgta gaaaccaaat tcagcacgga tcccatcccc tgagaagagc tgtagattac
    68821 catagtgccg ttaggtgcca gacttggcgt ttcatccagg aacgtggacg acagaacttg
    68881 tacgcctccc gttgccagat cttgtttggc aatgtgctgc tgcccaccgt tggagctgac
    68941 cattaccata aatttaccgt cgctgctgac atccgcatcc tggttctgcg aaccttccca
    69001 ggtaatacgt tgtggcgcac cgccgttgat attcacttta taaacctgcg gacgaccggc
    69061 ctggtcagaa gtaaatgcca ggttctggct gtccgggaac caggtcggtt cggtattgtt
    69121 actgcgacca tcagttacct ggcggatctg accagaagcc aaatccatta cgtacaggtt
    69181 caggctaccg gttttcgaca aggcgaatgc cagtttgctg ccgtctggcg agaatgcagg
    69241 tgcaccgttg tgacgcggga atgaagccac ctgacgtaca gcgccatttg ccagcgtctg
    69301 aataaccagc gcggaacgac cgctttcgaa ggtcacataa gccagtttag aaccgtctgg
    69361 tgaccacgcc ggagacatca gcggttgcgg tgaacggtga acgacaaact ggttgtaacc
    69421 gtcatagtca gatacgcgca gttcatacgg gaactgaccg ccgttagtct gaacaacgta
    69481 ggcaatacgg gtacggaacg cacctttaat accggtcagt ttttcaaata cttcgtcact
    69541 ggcggtatga ccagcataac gcagccactg cttgttcact ttgtacgagt tctgagcaag
    69601 tacagtaccc ggtgcgccgc cagtgtcaac aagttgataa gcaacattgt aagaaccatc
    69661 cggattcgga gtgacctgac cgacaaccac agcgtcaatg cccagcgcgg accatgcagc
    69721 tggttgtact tcctgcgcac tacccggctg ctgtggcaga cgagcacgat ctaacggatt
    69781 aaatttaccg ctgttacgca agtcagcagc aacgatgccg ccaatatctt caggtgccgc
    69841 accaggcccc gcccactgga aaggaacaac accaatagga cgaccggaat ctacaccgct
    69901 gtcgatcaca atgcggactt cagcatgcag aactgatgcc cacagtatga gaaaaccaaa
    69961 tgctactcgt aatgcctgct tcatcatatc tcccttatct ggaccgatgg cccacgataa
    70021 tttagcagaa tgttaacaaa ctaaaataca caaaactacc agaaccccgt ggcaaccggt
    70081 gcctgatgtt gaccgtcgga acagtcaaca tcgcgattac ggtttgaagt ccaatggcgc
    70141 gtttttgaac acttcatata ctgcctggct tggtggtttc gggatcttcg caagtttagc
    70201 tgctgccaac gcagcttgac aaagtgcggg atcgccacct tcaggtttga tatccagtaa
    70261 cataccatcg ggtgccagtt ttatgcgcag cgtacaggtt ttgcctgcat aggacgatgc
    70321 gtcatagaac ttactttcga tagcagattt aatctgcccg gcatagttat tgatatcggc
    70381 ccctgatgcg ccattgtttt tagtattacc actcccggca ggcgaagcat tgttcccttt
    70441 cgcccctccc cccgttttcg gtgcattctt accagagctt agctcaccga aaatatcatc
    70501 tgcctcagcg gcagcttttg ctgcagcggc tttttcagct gctgcttttg ccgctgccgc
    70561 ttttttgtct gcggcggctt tttctgccgc tgctttctta tcagctgctg ccttttcagc
    70621 agccgctttt tctgctgctt ttttgtcggc tgccgctttc tctgctgccg ctttcttatc
    70681 agctgcagcc ttttcagcag ccgctttttc tgctgctttt ttgtcggctg ccgctttctc
    70741 tgctgccgct ttcttctcag cttctgcctt ggctttttca gcagcttcgg ttgccgcttt
    70801 ctttcttgct tcagctgcag ctgcttctgc cgcttcagct ttcttcttca gcgccgcagc
    70861 agcagcctcg gcttttttct gcgcttcgac tgcggctttg gcggcttctg cttctgcttt
    70921 tttcttcgcg tctgccgccg ctttcttcgc tgcttcttcc gcagctttag catccgcttc
    70981 ggccttcgct ttagcatctg ccgccgcttt cgctgccgcc tcttccgctt gcttctgctt
    71041 taactcggcc tgttttgcgg cttcttcagc ctgctttttc tgctcctgag ccgctaaccg
    71101 ctctttctca agttgcttca ggcgttcctg ttcagccgct tgtttctcac gcagttcttc
    71161 agcagcctgc tgctctttca tcttgcgctg ctcatcagaa cgcttcgcgc ttgattcctg
    71221 gctttgcatg cgtttgtact gctcaactac cgcacctgaa tcaaccatga cagcgtcgat
    71281 ggacgaacca ccgccgcctc cggctgaagc ttctatattc tcatcgaacg aactccagat
    71341 cagcgccgca aataagatga catgcagcac tgctgaaata attatcgccc gcttgagctt
    71401 gtcgttttgt tcggttgcct ttgacactct cggtttccaa aaactgttcg cctgttaccc
    71461 gctctctttc aagcaaggga aacgcagatg tttagatagg ctgcgtcatt aaaccaaccg
    71521 atttcacacc cgcactatgt aacaagttca gtgctttaat tatttcatcg taaggcacat
    71581 cttttgcgcc accgatcaga aagaccgttt tcgggttggc cttgaaacgg ctggacactt
    71641 ccgccaccac ctgctctggt ggtaaacgct ccaggcgatc tttctcaacc accacggtgt
    71701 actgaccaat accagacact tcaacaatca ctggcggatt atcgttactg ctcaccgcct
    71761 gtgattcagt agcgtctggc agatcgacct ccacgctctg ggtgatgatg ggcgctgtcg
    71821 ccataaagat cagcaacagc accagcagta cgtccagcaa cggtacaatg ttgatttcgg
    71881 acttgagatc gcgacgacct cgtccacgcg ctctggccat ggcttacccc ttgttgctct
    71941 cgctaacggt aaacgcctgg cggtgcagaa tcgcggtaaa ctcttccata aagttgtcgt
    72001 aattcagttc cagtttgttt acgcgctggt tgagacggtt ataagccatt accgccggaa
    72061 ttgcggcgaa caaaccaatt gccgtcgcaa tcaacgcttc tgcgataccg ggcgcaacca
    72121 tttgcagtgt tgcttgtttt accgccccga gggcgataaa ggcgtgcatg atcccccaga
    72181 ccgtaccaaa cagaccaata tacgggctga tggagccaac cgtaccgagg aacggaatgt
    72241 gcgtttccag attttcaagt tcacgattca tggaaatacg catcgcacgc gacgcccctt
    72301 ccactacggc ttccggcgca tggctattgg cacgatgcag gcgcacaaac tctttgaagc
    72361 cgctgtaaaa gatttgttcc gaaccgctca gattatcccg tttcccctgg ctctcttgat
    72421 agaggcgaga gagttcgatt ccagaccaga atttatcttc aaacgcttcg gcttcgcgcg
    72481 ccgctgcgtt aagaatacgg gtccgctgga taataatggc ccaggatgcg attgaaaaac
    72541 caatcaaaat caacatgata agtttaacca gaaggctagc cttcaggaac aaatcaagga
    72601 tattcatgtc agtcactgct taaactccgc gacaatagac ttgggaagcg cacgaggctt
    72661 cattttgagt gggtcaacgc aaacaaccag aacctctgct tcattcaaca aagtattctc
    72721 ggcgttgaca atacgttgcg tgaaaaccaa agaggtgcca cgcattgatg ttatttcagt
    72781 ctgtatttcg agcatatcgt cgagccgcgc aggtgcgtaa tattccaccg tcattttacg
    72841 taccacaaag gcaacgcgtt cagccatcag cgcctgttga ctgaaatgat gatgacgcag
    72901 catctctgtg cgtgctcttt cataaaaagc gacgtaactg gcgtggtaca ccacaccacc
    72961 ggcatcggta tcttcatagt agacgcgaac cggccatcga aacagcgttg tattcacttt
    73021 acatcccggt aatgcaacaa aagttagagc ttttaaacgc tgctactata cgcgcgcgat
    73081 tgaggtttgg gaatgagggc aagttaaggg agcgtaaaaa tttatgggcc tgactcggcc
    73141 cataaatttt taaagagaat tctgatttaa aagaagaaga aaatcagccc gacaatgaga
    73201 acaatatcgg caagcaatgg gcaaaaaaac ccttgccaga gaaccttctg cggacgaaag
    73261 cccacgccgt gaatcacacc agcacagacg gcccacataa gcagtaaacc atgccagatt
    73321 tccagttcac tggtcttcgc ggcgaaacgt gatgggtccc aaaacataca tcctgctaac
    73381 agaagtgcca tcacgaagga aagcgcccgc agggggcgct tgtccattac cgcatacaag
    73441 gttgcgataa tcttactcat cagatgtctt cttgaccggc tttgcctgat tcgacgtgct
    73501 caagcgccag cgcggtgatt accccaaacg aacaggcaag aagcgttccc agaatccatg
    73561 cgaaatacca catttttagc tccttactta gtacagagag tgggtgttac gttcaatatc
    73621 ttctttggtg atacgaccga acattttcca gtaacaccag gcggtgtaga gcagaatgat
    73681 cggtaccaga accaccgcaa cccaggtcat gacgttaagc gtcagctggc tggaagttgc
    73741 atcccacatt gtcagacttg cgttcatcat ggtgctggac ggcatcacaa acgggaacat
    73801 tgcgataccg gcagtcagga tgatgcaggc cagcgtcagg gaggagaaaa caaacgccca
    73861 cgcggcttta tccatacgtg cagtcaggat ggtcagcagc ggcagaacca cacccagtgc
    73921 cggaatagcc cacagaattg gcgtgttgtt gaagttaacc agccatgcgc cagcttcacg
    73981 aaccacttct ttattcagcg ggttagaggc tgcgtaatgg tccattgtcg atttcacgac
    74041 ataaccatcg ataccgtaca tcacccatac gccagccagt gcgaagcaga ccagcgtcac
    74101 cagtgccgcc acctgagccg ttgcacgggt acgcaggtgc agttcgccca cggtacgcat
    74161 ttgcagatag gttgcgccct gagtaatgat catccctacg ctcaccacac ctgccagcag
    74221 gccgaacggg ttaagcagct ggaagaagtt accggtgtag tacagacgca gatattcatc
    74281 aacgttgaat ggtacgccct gcaacaggtt accgaacgct acaccaatca ccagcggcgg
    74341 aacgaagcta ccaatgaaga tgccccagtc ccacatgtta cgccagcggg tttcttcaat
    74401 cttggagcgg tagtcaaaac cgaccggacg gaagaacaaa gacgccagta cgaggatcat
    74461 cgccacatag aagccggaga acgcagcggc atagaccatc ggccaggcag caaacagtgc
    74521 accgcctgcg gtgatcagcc aaacctggtt accgtcccag tgtggtgcga tggagttaat
    74581 cataattcga cgctcggtgt cgttacgacc gaggaaacgg gtgagcatgc ccacccccat
    74641 gtcgaaaccg tcagtgactg caaaaccaat cagcagaacg ccaaccagca gccaccagat
    74701 aaaacgcaat acttcataat cgatcatttg acgactcctg tcttagcgtg ccggctgagt
    74761 agtcgtggaa gactgctcaa agtgatagcg accggttttc aggctgcttg ggccgaggcg
    74821 tgcaaacttg aacattaaga acaattctgc caccaggaac agggtataca ggccgcaaat
    74881 cagcaccatt gagaagatga gatcgcctgc ggtcagtgac gagttcgcca cagctgtcgg
    74941 cagcacttca ccgatagccc acggttggcg gccatattca gccacgaacc agcccgcttc
    75001 tacagcaatc cacggcagcg gaataccgta cagcgcggcg cgcagcagcc attttttctc
    75061 gccaatgcgg ttgcggatga cactccagaa agagagcgca atgattgcca gcagcaggaa
    75121 gccacacgcc accatgatac ggaacgcgaa gtacagcggc gctacacgcg gaatggagtc
    75181 tttggttgcc tgttgaatct gagcttcagt cgcatcagcc acgtttggcg tatagcgttt
    75241 cagcagcaga ccgtaaccga gatctttctt catgctattg aactggtcac gaacggcctg
    75301 gtcagtagaa ccagaacgca gttgttcgag cagagagtac gccttcatcc cgttacgaat
    75361 gcgttcttca tgctgcacca tcagttcttt cagaccgata actggagtat ccacggaacg
    75421 cgttgcaatg atgcccagcg cgtaagggat ctggatcgca aatttgttcg tctcctcttc
    75481 ctgatcagga atgccgaaca gagtaaaggc agcaggtgca ggttgcgttt cccactcggc
    75541 ttcaatagca gccagtttgg ttttctgcac gtcgcccatt tcgtagccgg attcatcacc
    75601 cagaacaata acagacagaa cggcagccat accgaagctg gcagcgatag caaaggagcg
    75661 tttagcgaag gcgaagtcac gacctttcag catataccat gcgctgatac cgaggatgaa
    75721 catcgcgcca gtcacataac cagaagctac ggtgtgaacg aatttcacct gagcaaccgg
    75781 gttaagcacc agctcggaga agctcaccat ctccatacgc atagtttcaa agttgaaatc
    75841 ggacgcgatt gggttttgca tccagccgtt tgcaaccaga atccacagtg cggacaggtt
    75901 tgaaccgagc gccaccagcc aggtgacaca catatgctga actttaccca gacgatccca
    75961 accgaagaag aacagaccta caaaggtgga ttcgaggaag aaggccatca gaccttcgat
    76021 tgccagcggc gcaccgaaga tatcccctac atagtgggaa tagtaagacc agttagtccc
    76081 gaactggaac tccatggtca gaccggtagc cacacccaga gcaaagttga taccaaacaa
    76141 cttgccccag aacttggtca tatctttata aatctgtttg ccggaaagga cgtagaccgt
    76201 ttccataatg gccagcagga acgccatacc gagcgtcagt ggcacaaaaa ggaagtggta
    76261 catcgcggtc aaggcaaact gtaagcgcga cagttcgact atatctaaca tcatgactcc
    76321 ttgctcatcg catgaagact ccgagagtga accccgttag aaagggtcac acgcatgccc
    76381 caatacaaaa ttatttgctc gcctctat
//
LOCUS       DAFGPF010000008        70893 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFGPF010000008 DAFGPF010000000
VERSION     DAFGPF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 70893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70893
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.008"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            119..562
                     /gene="cmtB"
                     /locus_tag="LSX49_000677"
     CDS             119..562
                     /gene="cmtB"
                     /locus_tag="LSX49_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HBL7167128.1"
                     /translation="MRLIDYFPESSISVIHSAKDWQEAIDFSMASLLDKNYISENYIQ
                     SIKDSTISNGPYYILAPGVAMPHARPECGALKTGMSLTLLKQGVYFPGKDEPIKLLIG
                     LSAADANSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG"
     gene            590..1978
                     /gene="cmtA"
                     /locus_tag="LSX49_000678"
     CDS             590..1978
                     /gene="cmtA"
                     /locus_tag="LSX49_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBL7167129.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYIDKSLEKRIPAGFEMVINNFSLGIAGMLFCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETKSEDEFTESANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            1993..3270
                     /locus_tag="LSX49_000679"
     CDS             1993..3270
                     /locus_tag="LSX49_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBL7167130.1"
                     /translation="MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVVVEVGKNLTGKYKKGQRFVLQPAMGLPSG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPARVVVVDIDDKRLAQV
                     QKLLPVELAASKGIELVYMNTKGMSDPVQTLRALTDDAGFDDVFVYAAVPSVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHIVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEKTHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            3267..4232
                     /gene="yggF"
                     /locus_tag="LSX49_000680"
     CDS             3267..4232
                     /gene="yggF"
                     /locus_tag="LSX49_000680"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HBL7167131.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAV
                     MAFAPRDSLLHAPDMYMKKLVVNRLAAGAIDLSLPLADNLRNVARALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAELIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            4254..4763
                     /gene="fumE"
                     /locus_tag="LSX49_000681"
     CDS             4254..4763
                     /gene="fumE"
                     /locus_tag="LSX49_000681"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HBL7167132.1"
                     /translation="MATLTEDDVLEQLNAQDNLFSFMKTAHSILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQD
                     ETPRFADDITWDFISNVNSITRNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            4760..5473
                     /locus_tag="LSX49_000682"
     CDS             4760..5473
                     /locus_tag="LSX49_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HBL7167133.1"
                     /translation="MKIELTVNGLKVQAQYSDDEIENVHKPLLRMLAALQTVNPQRRT
                     VVFLCAPPGTGKSTLTTFWEYLAQQDPELPAIQTLPMDGFHQYNSWLDVHQLRPFKGA
                     PETFNVAKLAENLCRVVEGDCTWPQYDRQKHDPVEDVLHVTAPLVIVEGNWLLLDDEK
                     WCQLAQFCDFSIFIKAPASALRERLVGRKLAGGLSLADAEAFYDRTDGPNVRRVLEES
                     LPANLTLMMTATGEYRLMD"
     gene            complement(5445..6122)
                     /locus_tag="LSX49_000683"
     CDS             complement(5445..6122)
                     /locus_tag="LSX49_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBL7167134.1"
                     /translation="MLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKST
                     LLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKIGVLFQEAENQLFHSTVADEIAFG
                     LILQKCPADEITQRTNAALQCCQLADTASAHPLDLHSAQRRMVAVACLEALSPPLLLL
                     DEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVN
                     PSDDIHP"
     gene            complement(6116..6793)
                     /locus_tag="LSX49_000684"
     CDS             complement(6116..6793)
                     /locus_tag="LSX49_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL7167135.1"
                     /translation="MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTL
                     AQLMAGWYPDFLPGEITGTGTLLGTPIGRLPLNEQSATIQLVQQSPYLQLSGCTFSVE
                     EEVAFGPENLCLAEKEIMARIDAALALTECQPLRHRHPATLSGGETQRVVIACAIAMQ
                     PKLLILDEAFSRLTPQAREMLLQRLQHWALERGSLIILFERHHTPFLNHCQQAWQLQN
                     GALQPLC"
     gene            complement(6781..7488)
                     /locus_tag="LSX49_000685"
     CDS             complement(6781..7488)
                     /locus_tag="LSX49_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL7167136.1"
                     /translation="MHPFTSLTLWALAACTTLILPTQTILPVYSAATFFCLIALKATR
                     RRAKYVVWLMFSLGAGLWLVHGGWLTEWLSGTPHSPERWAHAITLWLRILAIVSTSQL
                     WMQYVPVQRFIRALFASRLPPGVAYLFAGPLLVVEQLKRQLAIIHEAQCARGVPLDEG
                     WYQRLRAMPALIIPLTHNALNDLAVRGAALDMRAFRINNRRTTLWAPADSTLQCVARY
                     AMILLMLAEFGAWIWLR"
     gene            complement(7489..8067)
                     /locus_tag="LSX49_000686"
     CDS             complement(7489..8067)
                     /locus_tag="LSX49_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL7167137.1"
                     /translation="MARRHFSSQALVLIVISIAINMIGGQLASMVKLPIFLDSIGTLI
                     SAVLLGPIIGMLTGLLTNLLWGLLTDPIAAAFAPVAMVIGLVAGWLARAGWFRTLPKV
                     VVSGVIITLAVTVVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
                     VDKILTAVIVWLLLRQLPIRTTRHFPAMAAVR"
     gene            complement(8090..8521)
                     /locus_tag="LSX49_000687"
     CDS             complement(8090..8521)
                     /locus_tag="LSX49_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL7167138.1"
                     /translation="MMTLPYPYSSSARFYALRLLPGQEVLSQLRAFAQQQQLHAAWIA
                     GCTGSLTDVALRYAGQENTALLSGKFEVIALNGTLEQSGEHLHLCVSDPHGTMLGGHM
                     MPGCTVRTTLELVIGCLEELAFSRQLCALSGYDELHISPVK"
     gene            8893..9912
                     /gene="epd"
                     /locus_tag="LSX49_000688"
     CDS             8893..9912
                     /gene="epd"
                     /locus_tag="LSX49_000688"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HBL7167139.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            9962..11125
                     /gene="pgk"
                     /locus_tag="LSX49_000689"
     CDS             9962..11125
                     /gene="pgk"
                     /locus_tag="LSX49_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBL7167140.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            11339..12418
                     /gene="fbaA"
                     /locus_tag="LSX49_000690"
     CDS             11339..12418
                     /gene="fbaA"
                     /locus_tag="LSX49_000690"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HBL7167141.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            12609..13469
                     /gene="mscS"
                     /locus_tag="LSX49_000691"
     CDS             12609..13469
                     /gene="mscS"
                     /locus_tag="LSX49_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HBL7167142.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPARRNEFIIGVAYDSDIDQVKQILTDIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            13608..14243
                     /gene="argO"
                     /locus_tag="LSX49_000692"
     CDS             13608..14243
                     /gene="argO"
                     /locus_tag="LSX49_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HBL7167143.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAE
                     VLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            14336..15076
                     /locus_tag="LSX49_000693"
     CDS             14336..15076
                     /locus_tag="LSX49_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HBL7167144.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFNRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            15244..16140
                     /locus_tag="LSX49_000694"
                     /pseudo
     CDS             15244..16140
                     /locus_tag="LSX49_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(16137..17192)
                     /locus_tag="LSX49_000695"
     CDS             complement(16137..17192)
                     /locus_tag="LSX49_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HBL7167145.1"
                     /translation="MSNVQEWQQLANKELSRREKTVDSLVQQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLATHRGYD
                     SDNPRVAGDVGKAGVAIDTVEDIKVLFDQIPLDKMSVSMTMNGAVLPVLAFYIVAAEE
                     QGVTSDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCSGNMPRFNTISISG
                     YHMGEAGANCVQQVAFTLADRIEYIKAAISAGLKIDDFAPRLSFFFGIGMDLFMNVAM
                     LRAARYLWSEAVSGFGAQDPYNNVIRTTIDHCAHPMYRDYLHRYLENASGGHIHHDLS
                     HVFDLHRNLIATGSMLG"
     gene            complement(17395..18288)
                     /gene="argP"
                     /locus_tag="LSX49_000696"
     CDS             complement(17395..18288)
                     /gene="argP"
                     /locus_tag="LSX49_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HBL7167146.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            18429..18659
                     /locus_tag="LSX49_000697"
     CDS             18429..18659
                     /locus_tag="LSX49_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167147.1"
                     /translation="MHFAQRVRALVVLNGVALLPQFACKQGLANGELVRLFAPWSGIP
                     RPLYALFAGRKGMPAIARYFMDELTTRLANGV"
     gene            18715..19374
                     /gene="rpiA"
                     /locus_tag="LSX49_000698"
     CDS             18715..19374
                     /gene="rpiA"
                     /locus_tag="LSX49_000698"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBL7167148.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            19630..20862
                     /gene="serA"
                     /locus_tag="LSX49_000699"
     CDS             19630..20862
                     /gene="serA"
                     /locus_tag="LSX49_000699"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL7167149.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            21091..21150
                     /gene="ibsC"
                     /locus_tag="LSX49_000700"
     CDS             21091..21150
                     /gene="ibsC"
                     /locus_tag="LSX49_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HBL7167150.1"
                     /translation="MMRLVIILIVLLLISFSAY"
     gene            complement(21251..21853)
                     /locus_tag="LSX49_000701"
     CDS             complement(21251..21853)
                     /locus_tag="LSX49_000701"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBL7167151.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNKLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKMQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(21874..22057)
                     /gene="ssrS"
                     /locus_tag="LSX49_000702"
     ncRNA           complement(21874..22057)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LSX49_000702"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(22099..22428)
                     /gene="zapA"
                     /locus_tag="LSX49_000703"
     CDS             complement(22099..22428)
                     /gene="zapA"
                     /locus_tag="LSX49_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL7167152.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            22596..23174
                     /gene="ygfB"
                     /locus_tag="LSX49_000704"
     CDS             22596..23174
                     /gene="ygfB"
                     /locus_tag="LSX49_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HBL7167153.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            23200..24525
                     /gene="pepP"
                     /locus_tag="LSX49_000705"
     CDS             23200..24525
                     /gene="pepP"
                     /locus_tag="LSX49_000705"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HBL7167154.1"
                     /translation="MSDISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADEIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITALAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENECELRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSIQEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     AEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ"
     gene            24522..25700
                     /gene="ubiH"
                     /locus_tag="LSX49_000706"
                     /gene_synonym="visB"
     CDS             24522..25700
                     /gene="ubiH"
                     /locus_tag="LSX49_000706"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HBL7167155.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLESGETLTGRVLVA
                     ADGTHSALATACGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQYGPLAMLPMSDG
                     RCSLVWCHPLERREEVLSWSDEKFCRELQSAFGWRLGQITHAGKRSAYPLALTRAAKP
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAQERREDMGDYGVLCRYQQ
                     RRQRDREATIGVTDSLVHLFANRWTPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
                     "
     gene            25723..26925
                     /gene="ubiI"
                     /locus_tag="LSX49_000707"
                     /gene_synonym="visC"
     CDS             25723..26925
                     /gene="ubiI"
                     /locus_tag="LSX49_000707"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HBL7167156.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGIGLRVAVLEQRVPEPLAADA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRACCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWNKALQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQAGEDEFNRALNIAFDNRLGLCKVESERLVFPLTGRYA
                     RQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSAALMLAGMQGFRDLFSGANPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(26999..27082)
                     /locus_tag="LSX49_000708"
     CDS             complement(26999..27082)
                     /locus_tag="LSX49_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167157.1"
                     /translation="MSKNTKSKIRGIRKYNAKSQVKLVYFK"
     gene            27373..28467
                     /gene="gcvT"
                     /locus_tag="LSX49_000709"
     CDS             27373..28467
                     /gene="gcvT"
                     /locus_tag="LSX49_000709"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HBL7167158.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            28491..28880
                     /gene="gcvH"
                     /locus_tag="LSX49_000710"
     CDS             28491..28880
                     /gene="gcvH"
                     /locus_tag="LSX49_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBL7167159.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            28999..31872
                     /gene="gcvP"
                     /locus_tag="LSX49_000711"
     CDS             28999..31872
                     /gene="gcvP"
                     /locus_tag="LSX49_000711"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HBL7167160.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGALLQ
                     QVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDID
                     TLDKDVAHDSRSIQAAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLAEWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLIRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            complement(32038..33471)
                     /gene="bglA"
                     /locus_tag="LSX49_000712"
     CDS             complement(32038..33471)
                     /gene="bglA"
                     /locus_tag="LSX49_000712"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HBL7167161.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHG
                     VPREITKEVVPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMIDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASALAVKAAHRINPEMKVGCMLAMVPLYPYSCNPDDVMFAQKSMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKVEDDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GTGDMSRSRKKSFNWYKEVIASNGENL"
     gene            33516..33827
                     /locus_tag="LSX49_000713"
     CDS             33516..33827
                     /locus_tag="LSX49_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL7167162.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELKKVIADIYPDQTQFYVIEFKC
                     L"
     gene            33991..34650
                     /locus_tag="LSX49_000714"
     CDS             33991..34650
                     /locus_tag="LSX49_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBL7167163.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     VKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     V"
     gene            complement(34727..35707)
                     /gene="ygfZ"
                     /locus_tag="LSX49_000715"
     CDS             complement(34727..35707)
                     /gene="ygfZ"
                     /locus_tag="LSX49_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HBL7167164.1"
                     /translation="MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQ
                     VTADVSQMTEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARTALANLFSELPSREKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLTGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLRIEPLPYSLEE"
     gene            35950..36216
                     /gene="sdhE"
                     /locus_tag="LSX49_000716"
     CDS             35950..36216
                     /gene="sdhE"
                     /locus_tag="LSX49_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HBL7167165.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRTFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            36197..36604
                     /locus_tag="LSX49_000717"
     CDS             36197..36604
                     /locus_tag="LSX49_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HBL7167166.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLIPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWSIVKAPWMIKSGMMLRLRSD
                     SGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(36644..37165)
                     /gene="fldB"
                     /locus_tag="LSX49_000718"
     CDS             complement(36644..37165)
                     /gene="fldB"
                     /locus_tag="LSX49_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HBL7167167.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     MLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
                     CEQILNEMAEHYA"
     gene            37277..38173
                     /gene="xerD"
                     /locus_tag="LSX49_000719"
     CDS             37277..38173
                     /gene="xerD"
                     /locus_tag="LSX49_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBL7167168.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            38198..38908
                     /gene="dsbC"
                     /locus_tag="LSX49_000720"
     CDS             38198..38908
                     /gene="dsbC"
                     /locus_tag="LSX49_000720"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HBL7167169.1"
                     /translation="MKKGFMLFTLLAAFSGFVQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIW
                     CAKDKNKAFDDVMAGKSVAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQP
                     PKDMKEFLDEHQKMTSGK"
     gene            38914..40647
                     /gene="recJ"
                     /locus_tag="LSX49_000721"
     CDS             38914..40647
                     /gene="recJ"
                     /locus_tag="LSX49_000721"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBL7167170.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTD
                     HHLPGDTLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDPQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEEKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            40738..41836
                     /gene="prfB"
                     /locus_tag="LSX49_000722"
     CDS             join(40738..40812,40814..41836)
                     /gene="prfB"
                     /locus_tag="LSX49_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBL7167171.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            41846..43363
                     /gene="lysS"
                     /locus_tag="LSX49_000723"
     CDS             41846..43363
                     /gene="lysS"
                     /locus_tag="LSX49_000723"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBL7167172.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(43406..43954)
                     /gene="idi"
                     /locus_tag="LSX49_000724"
     CDS             complement(43406..43954)
                     /gene="idi"
                     /locus_tag="LSX49_000724"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBL7167173.1"
                     /translation="MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKG
                     QLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEEAVIRRCRYELGVEITPPESIYPDF
                     RYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLAAVLRGIDATPWAFSP
                     WMVMQATNREARKRLSAFTQLK"
     gene            44009..44080
                     /locus_tag="LSX49_000725"
     CDS             44009..44080
                     /locus_tag="LSX49_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167174.1"
                     /translation="MINQVSVYRQPPVLSGCRQVKTI"
     gene            complement(44077..44202)
                     /locus_tag="LSX49_000726"
     CDS             complement(44077..44202)
                     /locus_tag="LSX49_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167175.1"
                     /translation="MNLLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF"
     gene            complement(44204..45652)
                     /gene="uacT"
                     /locus_tag="LSX49_000727"
     CDS             complement(44204..45652)
                     /gene="uacT"
                     /locus_tag="LSX49_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate/proton symporter UacT"
                     /protein_id="HBL7167176.1"
                     /translation="MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAG
                     AVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFA
                     AVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
                     SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFG
                     FLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFL
                     ALGEIVGRKLSSQDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVC
                     ISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYN
                     LYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHAD
                     LVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE"
     gene            46088..48007
                     /gene="ygfT"
                     /locus_tag="LSX49_000728"
     CDS             46088..48007
                     /gene="ygfT"
                     /locus_tag="LSX49_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HBL7167177.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIDVCPTQALRLMDDKGLQQIKVARQRKTAAGKASS
                     DAQPSRSAALLPVNSRKGADKISASERKTHFGEIYCGLDPQQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCADILARAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDISFNEL
                     TAEYDAVFLGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESAEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNAREEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHTMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAS"
     gene            48007..48495
                     /locus_tag="LSX49_000729"
     CDS             48007..48495
                     /locus_tag="LSX49_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBL7167178.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADIFLPRLKVQ
                     RLDSISAPVMCHQCENAPCVGACPVGALTMGEQVVQANSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASSEN
                     PL"
     gene            complement(48531..49898)
                     /gene="ghxQ"
                     /locus_tag="LSX49_000730"
                     /gene_synonym="ygfQ"
     CDS             complement(48531..49898)
                     /gene="ghxQ"
                     /locus_tag="LSX49_000730"
                     /gene_synonym="ygfQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxQ"
                     /protein_id="HBL7167179.1"
                     /translation="MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGVLFLMILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(49934..51250)
                     /gene="guaD"
                     /locus_tag="LSX49_000731"
     CDS             complement(49934..51250)
                     /gene="guaD"
                     /locus_tag="LSX49_000731"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HBL7167180.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTVDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWEDGKHQIPDTIRVRDYRGKLIVPGFIDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
     gene            complement(51268..52668)
                     /gene="xanQ"
                     /locus_tag="LSX49_000732"
     CDS             complement(51268..52668)
                     /gene="xanQ"
                     /locus_tag="LSX49_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HBL7167181.1"
                     /translation="MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGLGISYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGY
                     RQENVLPGITSAEEMD"
     gene            complement(52833..55703)
                     /locus_tag="LSX49_000733"
     CDS             complement(52833..55703)
                     /locus_tag="LSX49_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HBL7167182.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIDAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEDIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFHGAQILGEPVADVQLATPGVVRGKKGEVSFGEIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            complement(55700..56479)
                     /locus_tag="LSX49_000734"
     CDS             complement(55700..56479)
                     /locus_tag="LSX49_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HBL7167183.1"
                     /translation="MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWIDWDNGALRIGAMSRLQPLRDARFIPAALREALGFVYSRHVRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVAITDHDGMRIALDGVASKALRLHDVETQNLEGNALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            complement(56530..57858)
                     /gene="ssnA"
                     /locus_tag="LSX49_000735"
     CDS             complement(56530..57858)
                     /gene="ssnA"
                     /locus_tag="LSX49_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBL7167184.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIDGSLSTLRNAFLKVGLRAMTCFETTDRN
                     NGIKELQEGVEENIRFTRQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLREAVK
                     STGRGLHIHVAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDIVLL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALANGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            complement(57861..60959)
                     /gene="ygfK"
                     /locus_tag="LSX49_000736"
     CDS             complement(57861..60959)
                     /gene="ygfK"
                     /locus_tag="LSX49_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HBL7167185.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKSKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDALNKLLQDEAFLARHGLQEKRESLQALPARIPTS
                     MVQGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWELNHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPD
                     LTVEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATVVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLHVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDTILSRENIRSH
                     QNDKYWNNVNPAEIYQRKGDISVTLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLSQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLGRV
                     EV"
     gene            complement(61281..61859)
                     /gene="mocA"
                     /locus_tag="LSX49_000737"
     CDS             complement(61281..61859)
                     /gene="mocA"
                     /locus_tag="LSX49_000737"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBL7167186.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVQTEHCFLTHGDM
                     PTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNVTNMRQALLMG
                     EHYSVEIENAEIILDIDTPDDFITAKKRYTEI"
     gene            61963..62733
                     /gene="yqeC"
                     /locus_tag="LSX49_000738"
     CDS             61963..62733
                     /gene="yqeC"
                     /locus_tag="LSX49_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBL7167187.1"
                     /translation="MKSIIDPSALFIDLGAQKRPTVISIVGAGGKTSLLFWLAELFQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASFISPISFCFHCWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHILGAKV
                     STENVHRWSQFADITGLTPDAPLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHNVEAIWLGDIQEHPAIARRFVN"
     gene            62781..64406
                     /locus_tag="LSX49_000739"
     CDS             62781..64406
                     /locus_tag="LSX49_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBL7167188.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLHQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMVDPTCSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFT
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(64447..65379)
                     /gene="arcC"
                     /locus_tag="LSX49_000740"
     CDS             complement(64447..65379)
                     /gene="arcC"
                     /locus_tag="LSX49_000740"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL7167189.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAELLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(65427..66812)
                     /gene="hyuA"
                     /locus_tag="LSX49_000741"
     CDS             complement(65427..66812)
                     /gene="hyuA"
                     /locus_tag="LSX49_000741"
                     /EC_number="3.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HBL7167190.1"
                     /translation="MRVLIKNGIVVNADGQAKQDLLIESGIVRQLGTDISPQLPCEEI
                     DASGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRISPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            complement(66865..68076)
                     /locus_tag="LSX49_000742"
     CDS             complement(66865..68076)
                     /locus_tag="LSX49_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBL7167191.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            complement(68134..69330)
                     /gene="dpaL"
                     /locus_tag="LSX49_000743"
     CDS             complement(68134..69330)
                     /gene="dpaL"
                     /locus_tag="LSX49_000743"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBL7167192.1"
                     /translation="MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEG
                     KHAVAP"
     gene            complement(69388..70575)
                     /gene="ygeW"
                     /locus_tag="LSX49_000744"
     CDS             complement(69388..70575)
                     /gene="ygeW"
                     /locus_tag="LSX49_000744"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HBL7167193.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
BASE COUNT        17173 a        17560 c        18799 g        17361 t
ORIGIN      
        1 tttattattt ttactcatga ggtttttctt ctcgcgtgcc caattgcttt cattaaactg
       61 cacgagtatt ttatttttac cgccggacgg taccctaaaa ataaaataag gataatttat
      121 gcggcttatt gattattttc cagaatcatc aatctcagtt atacattcag caaaagactg
      181 gcaggaagct atcgatttct cgatggcatc attgctggat aaaaactata tcagcgagaa
      241 ttacattcaa tctattaaag actccaccat cagcaatggt ccttattata ttctcgcacc
      301 aggcgtggca atgcctcatg cgcgaccgga atgtggggcg cttaaaaccg ggatgtcttt
      361 gacgttactt aaacaaggcg tttatttccc ggggaaggac gaaccgatta aattactcat
      421 cgggctttct gctgccgatg ccaattcgca cattggcgct attcaggcgt taagtgaatt
      481 actgtgcgaa gaagaaatac tcgaacaact cttaacagca tcatcagaaa aacaattagc
      541 ggacattatc agccgcggat aattactctc tcctctacag gataatatta tggaaaacaa
      601 gtctgctcgt gcaaaggtcc aggcttttgg gggctttttg actgcaatgg tcatccccaa
      661 tatcggtgct tttattgcct ggggatttat aacggcatta tttattccca ccggctggct
      721 gccgaatgaa catttcgcca aaattgttgg tccgatgatt acctatttat tgcccgtgat
      781 gattggttct accggtggtc atctggtcgg cggtaaacgc ggcgcggtca tgggcggaat
      841 tggtacgatt ggtgtgatcg tcggcgctga aatcccgatg ttccttggct cgatgattat
      901 ggggccgctc ggtggtctgg tgattaaata tatcgacaag tcgctggaaa aacgcatacc
      961 tgctggtttt gagatggtta tcaataactt ctcattaggt atcgcgggga tgctcttttg
     1021 tctgctgggt tttgaagtta tcggtccggc ggtgttaatt gctaatactt tcgtcaaaga
     1081 gtgtattgag gcgctggtac atgcgggtta tctgcctttg ctgtcagtca tcaatgaacc
     1141 ggcgaaagtg cttttcctta ataatgcgat tgatcagggc gtctattatc cgctgggaat
     1201 gcaacaggct tcggttaacg gtaaatccat cttcttcatg gtggcctcca acccaggtcc
     1261 tggtctgggg ctgctgctgg cgtttacctt gtttggtaaa gggatgagta aacgttctgc
     1321 gcccggggcg atgattattc acttcctcgg tgggatccac gaactgtatt tcccgtatgt
     1381 gctgatgaag ccgctgacca ttattgccat gattgcgggc ggtatgtctg gcacctggat
     1441 gtttaactta ctggacggtg gtctggtggc tggcccaagt ccggggtcta tctttgctta
     1501 cctggcactg acgccgaaag gctcgttcct ggcgacaatt gccggtgtta cggtaggtac
     1561 cctggtgtcc tttgctatca cttcgctgat actgaagatg gaaaaaacgg tggaaacgaa
     1621 gagcgaagat gagtttaccg agtcagccaa tgcggttaag gcgatgaaac aagaaggtgc
     1681 attctcgtta agccgtgtta agcgtattgc ctttgtttgc gatgcaggga tgggctccag
     1741 tgcgatgggc gcaaccacct tccgtaaacg cctggaaaaa gcggggctgg caatagaagt
     1801 aaaacattac gccatagaaa acgtgcctgc ggatgcggat atcgtcgtta ctcacgccag
     1861 tctggaaggg cgcgtgaaac gtgtgacgga taaaccactg atattgatta ataactatat
     1921 tggcgatcca aaactcgaca ctttatttaa tcaattaacc gctgaacata aacactgatt
     1981 acagaggtaa aaatgaaaac caaagttgct gctatttatg gcaagcggga tgtccgtctg
     2041 cgcgaatttg aactgccaga aattactgat aatgaactgt tagtgagtgt aatttctgac
     2101 agcgtttgtt tatccacctg gaaagcggcg ttgcttggta gtgaacataa acgcgtcccc
     2161 gacgatttag aaaatcatcc ggttattacc gggcatgaat gtgctggggt tgttgtcgaa
     2221 gtgggtaaaa atctcactgg caaatataaa aaagggcagc gttttgtatt gcaaccggcg
     2281 atggggctac caagcggata ttcagccgga tacagctacg aatattttgg tggcaatgcc
     2341 acctatatga ttattcccga aatcgcgatt aatttaggct gtgtattacc gtatcacggc
     2401 tcttattttg ctgcggcgtc gctggcagag cctatgtgct gcattattgg tgcttatcat
     2461 gccaattatc acaccacgca atatgtttat gagcatcgta tgggcgtcaa acctggcggc
     2521 aatattgccc tgctggcgtg tgctggcccg atgggcattg gcgctatcga ttacgccatt
     2581 aacggcggca tacaaccggc gcgggtggtg gtagtcgata tcgacgacaa acggctggcg
     2641 caggtgcaga agttgctgcc ggtggagctg gcggccagta aaggcattga gctggtgtat
     2701 atgaatacca aagggatgag cgatccggtc cagacgctgc gggcgctgac ggatgatgcc
     2761 ggatttgatg acgtatttgt ctatgcagcg gtgccttcag tcgtcgagat ggctgatgaa
     2821 ttactggctg aagatggctg cctgaacttc tttgccggtc cgacggataa aaacttcaaa
     2881 gtgccgttta atttctacaa cgtccattac aacagtacgc acattgtcgg cacgtctggc
     2941 ggttccacgg acgacatgaa agaggcgatt gcccttagcg ccacggggca gttacagccg
     3001 tcgtttatgg tgacccatat tggtggcctg gatgcggtgc cagaaaccgt gctcaatctg
     3061 ccggatatcc ctggcggtaa aaaactcatt tataacggcg tgaccatgcc gctgaccgcc
     3121 attgccgatt ttgccgaaaa aggcaaaacc gatccgctgt ttaaagagct ggcgcggctg
     3181 gttgagaaaa cgcacggtat ctggaatgaa caggccgaga aatatctgct ggcacaattt
     3241 ggcgttgata ttggggaggc cgcgcaatga tgtccctggc gtggccatta tttcgcgtta
     3301 cggaacaggc agcgttggct gcctggccgc aaaccggctg tggcgacaaa aataaaattg
     3361 atggccttgc ggtcaccgcg atgcgccagg cattaaacga cgttgctttt cgtgggcgag
     3421 tggttatcgg cgagggggaa attgaccatg cgccgatgct gtggattggc gaagaggtgg
     3481 gcaaaggcga tgggccagaa gtcgatatcg cggtcgatcc cattgaaggc acgcggatgg
     3541 tggcgatggg gcagagcaat gcgctggcgg tcatggcttt cgcccctcga gatagcctgt
     3601 tacatgcgcc cgatatgtat atgaaaaagc tggttgttaa tcgactggct gccggggcga
     3661 tagatctgtc tttgcctctg gcggacaact tgcgtaacgt ggcgcgggcg ttaggtaaac
     3721 cgctggacaa gctgcgcatg gttacgctgg ataaaccgcg cctgagtgcc gcaattgagg
     3781 aagcaacaca gctcggcgtg aaggtttttg ccctgccgga tggcgatgtc gccgccagcg
     3841 tgctgacttg ctggcaggat aatccttacg atgtgatgta caccatcggt ggcgcaccgg
     3901 aaggtgttat ttctgcctgt gccgttaaag cattaggcgg ggatatgcag gccgagctga
     3961 ttgacttttg tcaggctaaa ggggattaca cggaaaatcg gcagattgca gagcaggagc
     4021 gcaagcgttg caaggcaatg ggcgttgacg ttaaccgtgt atactcgctc gatgaactgg
     4081 tgagggggaa cgatatcctc tttagcgcta cgggcgtgac gggcggcgag ttggtgaacg
     4141 gtatccaaca gacggcgaat ggggtgcgga cgcagacatt actgatcggc ggcgcggacc
     4201 aaacgtgtaa tataatagac tccctgcatt gatggtgatc tatcggaaga ccaatggcga
     4261 cgctgacaga agatgatgtg cttgagcaac tgaatgcaca ggacaattta ttttcattta
     4321 tgaaaactgc gcattctatt ttgctccagg ggatacgcca gtttctgccg tcgctgtttg
     4381 tcgataacga tgaagagatc gtcgaatatg cagtgaagcc gttactcgcc caaagcggcc
     4441 cgcttgacga tattgatgtt gcgctgcgtt tgatttatgc gctggggaaa atggataaat
     4501 ggctgtacgc cgatatcacg catttttccc agttttggca ttacctgaac gaacaggatg
     4561 aaacgcccag atttgctgat gacataacct gggattttat cagcaacgtc aatagcataa
     4621 cccgcaatgc gacgctctat gacgcgttga aagcgatgaa gttcgccgat ttcgccgtct
     4681 ggtcagaggc gcgttttagc gggatggtca aaacggcgct gacgctggca gtaacgacca
     4741 ccttaaagga attaacgccg tgaaaatcga actgacggtg aatggactaa aggtacaggc
     4801 gcagtactct gatgatgaaa ttgaaaatgt acataaacca ttgctgcgta tgctggcggc
     4861 cttacagaca gtaaatccgc agcggcgtac ggtggttttt ctttgcgctc cgccggggac
     4921 gggtaaatct accctaacca ccttctggga atatctcgcg caacaagacc cggaactgcc
     4981 cgctattcag acgctgccga tggatggttt tcaccagtac aatagctggc tggatgtgca
     5041 tcaattgcga cccttcaaag gcgcaccaga gacattcaac gttgcgaaac tggcggaaaa
     5101 tctgtgccgg gttgtggaag gggattgtac gtggccgcag tacgatcgac aaaagcatga
     5161 tcctgttgaa gatgtgttgc acgttaccgc accactcgtc atcgtcgaag gaaactggtt
     5221 gttgttggac gacgagaagt ggtgccagct tgcgcaattt tgtgatttct cgatctttat
     5281 caaagctccc gcatctgcgt tgcgggagcg tctggtgggg cgcaagctgg cgggagggtt
     5341 atcgctggca gacgcagaag ccttttatga ccgtaccgac gggccgaatg ttcgccgggt
     5401 gctggaagag agtctgcctg caaatttgac cttaatgatg accgctacgg gtgaatatcg
     5461 tctgatggat taacgttcct gattacacca tcttccagtc gcaccacacg agagaaatga
     5521 cgccgggtaa atgcggcgtc atgactgatt gctacgacgc tcgtgcctcg ctggcggcac
     5581 ttttccagcc agctttcaaa cacgctcaac caattttcgt caaaatcccg actcggctcg
     5641 tccagtagca atagtggcgg agagagtgct tccaggcagg cgacggcgac catccgtcgc
     5701 tgcgcactat gcagatctaa cggatgcgcg ctggcagtgt ctgctaactg acagcattgc
     5761 agggcagcat tggtacgttg agtgatttca tccgccgggc atttttgcag tatcaaacca
     5821 aatgcgattt cgtcagcaac ggtgctgtga aaaagctgat tttccgcttc ctgaaacagt
     5881 acgccaatct ttgccgcgcg ctggcggttt ttcaggtttt tcatcgcttg ttgttgcagc
     5941 ataaccgtac cggctgtggg cgtaagaaga cctgccatta ctcgtaacag cgtcgatttt
     6001 cccgcgccat tgtcgccggt cagcgccagc cattcacctt gtttgagttg cagagaaatg
     6061 tcgcaaagac aatccgtagc cgcgccaggc cagcgataag atatctgatt taacgttaac
     6121 atagtggctg gagcgctccg ttttgcaatt gccacgcttg ctggcagtgg ttcaggaaag
     6181 gtgtgtgatg acgttcaaaa agaataatca gcgaaccacg ttcaagcgcc cagtgttgta
     6241 agcgctgcaa cagcatttcg cgggcctgcg gcgtcaggcg gctaaaggct tcatcaagaa
     6301 ttaagagctt tggctgcatc gcgatggcgc aggcgatgac cacacgctgt gtctctccac
     6361 cggagagtgt tgccgggtga cgatggcgca acggctggca ctcggtcagg gccagggcgg
     6421 cgtcaatccg cgccataatc tctttttcag caagacacag attttctggc ccaaaggcaa
     6481 cttcttcttc cacgctaaag gtacagccgg agagctgcaa atagggcgat tgctggacga
     6541 gctggatggt ggcggattgt tcattaagcg ggagacgccc aatgggcgta ccgagaagcg
     6601 tccccgtgcc ggttatctct cctggtagaa agtccggata ccagcccgcc atcagctgtg
     6661 ccagcgtact tttgccactg ccgttgtcac caaagatggc gaccatcccc ggtttgacat
     6721 agtgaaagtc ataacagaac ggaggatgcg ttgagtgtgt cgggcaatag cgaaactgtt
     6781 ctaacgtaac catatccacg ctccgaattc agccagcatt agcaatatca tggcgtaacg
     6841 tgctacgcat tgtagggtgc tatcggctgg tgcccataac gtagtgcgcc tattgttgat
     6901 tcgaaatgcc cgcatatcca gcgccgcacc acggacagca agatcgttta gcgcattgtg
     6961 tgttagcgga ataattaacg cgggcatcgc acgtaaacgc tgataccagc cctcatccag
     7021 cggcacgccg cgggcgcact gcgcttcatg aataatcgcc aattgccgtt ttaactgctc
     7081 aacgaccaat aacggcccgg caaacagata agcgacgccc ggcggcaggc gagaagcaaa
     7141 caaagcgcgg ataaaacgtt gcacggggac gtactgcatc cacaactgtg aggttgaaac
     7201 aatcgccaga atccgcaacc agagcgtaat agcatgcgcc caccgttctg gagagtgtgg
     7261 cgtgccgctt agccattctg tcagccagcc accgtgcacc agccacagtc cagcccccag
     7321 cgagaacatc agccagacga catattttgc ccgccgccgc gtggccttta gcgcaataag
     7381 gcagaaaaag gtcgccgcgc tatagactgg caatattgtc tgtgtaggca ggataagcgt
     7441 ggtgcaggcc gccagcgccc acagcgttaa ggatgtaaaa ggatgcattt agcgcacggc
     7501 agccattgcc ggaaaatggc gcgtggtgcg aatcggcagc tgacgcagta aaagccagac
     7561 tatcaccgct gtaagaattt tatcgaccag gttcgcgcct atcaccgtaa tcgccaccga
     7621 ctccaccagg ttttgcccca tcgagtgcat ccaggcaacg aacaaatcgg ctccgcttcc
     7681 tgtcacgccg ccgaacagcg cagtacgcag cggtacagcg acgaccgtta ccgcaagcgt
     7741 aataatcacg ccgctaacaa cgacttttgg cagggtgcga aaccaacccg ctcgcgccag
     7801 ccaaccggcg accaggccga tgaccatcgc gacgggcgca aatgcggcgg cgatcgggtc
     7861 ggtcagcaat ccccagagta aattggtcag taaaccggtc agcatcccga ttatcggacc
     7921 aagcagtacc gcgctaataa gtgtgccgat ggagtcgaga aaaataggta atttaaccat
     7981 gctggccagt tgcccgccga tcatattgat ggcgatagag ataacgatca acaccagtgc
     8041 ctgactggaa aagtggcgac gcgccataag aaaacctctc tgaaaatagt tatttaacgg
     8101 gggaaatatg caactcgtcg taaccagaaa gcgcgcaaag ctggcggcta aacgccagtt
     8161 cctcaaggca gccgatcacc agttcaagcg tggtccgcac ggtacagccg ggcatcatat
     8221 gaccgccaag catcgtgccg tgtggatcgg aaacgcagag atgaagatgt tcaccactct
     8281 gttccagcgt gccgttcaat gcgatgactt cgaacttacc gcttagcagg gcagtgtttt
     8341 cttgcccggc atagcgtaag gcgacgtcag tcagactgcc ggtacaacct gcaatccacg
     8401 cggcgtgaag ttgttgttgc tgcgcgaagg cgcgtaattg ggagagaact tcctgcccgg
     8461 ggagcaggcg cagcgcgtaa aagcgtgcgg aggaagaata tgggtagggc aatgtcatca
     8521 ttggagtact ccgaaactcg gacgtattgc ggataatatc gacgctgcat cagtcatatt
     8581 ctgatataag tcagggtttg tgaccgcaca acgaaaagat attgctacgc ttattcgtga
     8641 ttctgcaaag tggaataaat tccacagggg cggggatgaa aacgtgacat aagtcagata
     8701 attgtcttct ttgactggac aaacattcct tttattccac gtttcgctta tcctagctga
     8761 agcgtttcag tcgattaaat gttcgacaat taaccaatca gtcgcagttt gcgacaggta
     8821 aggtttcccc gaacgatttg ctggattact ctgtctggca aatttgctca gggaaaacct
     8881 tgcaggagat ctatgaccgt acgcgtagcg ataaatggct tcggtcgcat cgggcgtaat
     8941 gtggttcgtg ctttgtatga atccggacgc cgtgcggaaa ttaccgtggt ggcaatcaac
     9001 gaactggcgg atgctgcggg catggcgcat ttgttgaaat atgacaccag ccatggccgt
     9061 tttgcatggg aagtacgaca ggaacgcgat caactttttg ttggtgatga cgccatccgt
     9121 gtattgcatg aacgttcact gcaatcgctc ccctggcgtg aacttggcgt tgatgtagtc
     9181 ctcgactgca ccggcgtata tggctcccgc gagcatggtg aagcacacat tgccgccggg
     9241 gctaaaaaag tgctcttttc acatcctggc agtaacgatc tcgacgcgac cgttgtttat
     9301 ggcgtcaatc aggatcaact tcgtgcggaa caccgcatcg tttctaatgc ttcctgtacc
     9361 acgaattgca taattcccgt catcaaattg ttagatgatg cgtacggtat tgagtctggc
     9421 actgtgacca caattcactc cgccatgcat gatcaacagg ttattgatgc ataccatcct
     9481 gacctgcgtc gcactcgggc agccagtcag tcgatcattc cggtcgatac taaactggcc
     9541 gccggtatca cacgattttt tccgcaattt aacgatcgct ttgaggcgat tgcggtacgt
     9601 gtgccaacca taaatgtgac ggcaatcgat ttaagcgtga cggtgaagaa acctgtaaaa
     9661 gccaatgaag tcaacctgtt gctgcaaaaa gcagcacaag gtgcatttca tggtatagtt
     9721 gactatacgg aattgccgtt ggtctctgta gattttaacc acgatccgca cagtgccatt
     9781 gtcgatggca ctcaaacccg ggtcagtggc gcacacctga tcaaaacgtt ggtctggtgc
     9841 gataacgaat ggggctttgc taaccgaatg ctcgacacga cgttagctat ggctactgtt
     9901 gctttcaggt aagacgcaag cagcgtctac aaaactttta gaatcaacga gaggattcac
     9961 catgtctgta attaagatga ccgatctgga tcttgctggg aaacgtgtat ttatccgtgc
    10021 ggatctgaac gtaccagtaa aagacgggaa agtaaccagc gacgcgcgta tccgtgcttc
    10081 tctgccgacc atcgaactgg ccctgaaaca aggcgcaaaa gtgatggtaa cttcccacct
    10141 gggtcgtcct accgaaggcg agtacaacga agaattctct ctgctgccgg ttgttaacta
    10201 cctgaaagac aaactgtcta acccggttcg tctggttaaa gattacctcg acggcgttga
    10261 cgttgctgaa ggtgaactgg ttgttctgga aaacgttcgc ttcaacaaag gcgagaagaa
    10321 agacgacgaa actctgtcca aaaaatacgc tgcactgtgt gacgtgttcg taatggacgc
    10381 attcggtact gctcaccgcg cgcaggcttc tactcacggt atcggtaaat tcgctgacgt
    10441 tgcgtgcgca ggcccgctgc tggcagctga actggacgcg ctgggtaaag cactgaaaga
    10501 acctgctcgc ccgatggtgg ctatcgttgg tggttctaaa gtatctacca aactgaccgt
    10561 tctggactcc ctgtctaaaa tcgctgacca gctgatcgtt ggtggtggta ttgctaacac
    10621 ctttattgcg gcacaaggcc acgatgtggg taaatccctg tacgaagctg acctggttga
    10681 cgaagctaaa cgtctgctga ccacctgcaa catcccggtt ccgtctgatg ttcgcgtagc
    10741 aaccgagttc tctgaaactg caccggctac cctgaaatct gttaacgatg tgaaagctga
    10801 cgagcagatc ctggatatcg gtgatgcttc cgctcaggaa ctggctgaaa tcctgaagaa
    10861 tgcgaaaacc attctgtgga acggtccggt tggcgtgttc gaattcccga acttccgcaa
    10921 aggtactgaa atcgtggcta acgctatcgc agacagcgaa gcgttctcca tcgctggcgg
    10981 cggcgacact ctggcagcaa tcgacctgtt cggcattgct gacaaaatct cctacatctc
    11041 cactggcggc ggcgcattcc tcgaattcgt ggaaggtaaa gtactgcctg cagtagcgat
    11101 gctcgaagag cgcgctaaga agtaaaaaat cacagggcag ggaaacctgc ccttgtttca
    11161 gcgcgctttt agagcacgca ctttttcata ctctaaataa ttcgagttgc aggaaggcga
    11221 caagagagtg aatcccagga gcttacataa gtaagtgatt ggggtgagcg aacgcagacg
    11281 cagcacatgc aacttgaagt atgacgagta taaggcccga cgatacagga caagagacat
    11341 gtctaagatt tttgatttcg taaaacctgg cgtaatcact ggtgatgacg tacagaaagt
    11401 tttccaggta gcaaaagaaa acaacttcgc actgccagca gtaaactgcg tcggtactga
    11461 ctccatcaac gccgtgctgg aaaccgctgc taaagttaaa gcgccggtta tcgttcagtt
    11521 ctccaacggt ggtgcttcct ttatcgctgg taaaggcgtg aaatctgacg ttccgcaggg
    11581 tgctgctatc ctgggcgcga tctctggtgc gcatcacgtt caccagatgg ctgaacatta
    11641 tggtgttccg gttatcctgc acaccgacca ctgcgcgaag aaactgctgc cgtggatcga
    11701 cggtctgctg gacgcgggtg aaaaacactt cgcagctacc ggcaagccgc tgttctcttc
    11761 tcacatgatc gacctgtctg aagaatctct gcaagagaac atcgaaatct gctctaaata
    11821 cctggagcgc atgtccaaaa tcggcatgac tctggaaatc gaactgggtt gcaccggtgg
    11881 tgaagaagac ggcgtggaca acagccacat ggacgcttct gcactgtaca cccagccgga
    11941 agacgttgat tatgcgtata ccgagctgag caaaatcagc ccgcgtttca ccatcgcagc
    12001 gtccttcggt aacgtacacg gtgtttacaa gccgggtaac gttgttctga ctccgaccat
    12061 cctgcgcgac tctcaggaat atgtttctaa gaaacacaac ctgccgcaca acagcctgaa
    12121 cttcgtattc cacggtggtt ccggttctac tgctcaggaa atcaaagact ccgtaagcta
    12181 cggcgtagtg aaaatgaaca tcgataccga tacccaatgg gcaacctggg aaggcgttct
    12241 gaactactac aaagcgaacg aagcttacct gcagggtcag ctgggtaacc cgaaaggcga
    12301 agatcagccg aacaagaaat actacgatcc gcgcgtatgg ctgcgtgccg gtcagacttc
    12361 gatgatcgct cgtctggaaa aagcattcca ggaactgaac gcgatcgacg ttctgtaagt
    12421 cattcttttc tgcttatctc aaggcccgct ctgcgggtct ttttttcgcc aaaagcaagg
    12481 tgatgcagat gagaaatctg tgatctattt ggcaaaatta tgctttattg tttacccttg
    12541 tcagactgcc cgccataagg cggcggagtg tatttctcca ttttgagtca gttgaaaagg
    12601 aatattgaat ggaagatttg aatgttgtcg atagcataaa cggcgcggga agctggctgg
    12661 tggctaacca ggcgctgctg ctaagttatg cagtaaacat cgtggcggca ctcgcgatca
    12721 tcatcgttgg tttgattatc gcgcggatga tttccaacgc ggtgaatcgc ctgatgatct
    12781 cccgtaaaat cgatgccact gttgctgatt ttctttctgc attagtccgt tacggaatta
    12841 tcgcctttac gctaatcgct gcactggggc gcgtgggcgt acaaacagcg tcagtcattg
    12901 ctgtactcgg tgccgcaggc ttagctgttg gtctggcttt gcaggggtca ctgtctaacc
    12961 tggccgctgg cgtgttactt gtcatgttcc gcccgttccg tgccggtgaa tatgttgacc
    13021 tcggcggcgt agccggcact gtgctgagtg tgcagatttt ctccaccacc atgcgtactg
    13081 cagacggtaa aattatcgtt attccgaatg gtaaaattat tgccgggaat attattaact
    13141 tctcccgcga gccagctcgc cgtaacgaat ttattattgg cgtggcgtat gattccgata
    13201 tcgatcaggt taagcagatc ctgaccgata ttatccagtc tgaagatcgc attttgaaag
    13261 atcgcgaaat gactgtgcgt ctgaacgaac ttggtgcatc gtcgattaat ttcgtggtcc
    13321 gagtctggag caacagcggc gatctgcaaa acgtgtactg ggatgtgctg gagcgtatta
    13381 aacgtgaatt tgatgccgcc ggtatcagct tcccgtatcc gcaaatggat gtgaacttta
    13441 agcgggtgaa agaagacaaa gctgcgtaat caacgctgag gccagataat actctctggc
    13501 ctctctctta ttagtttttc tgattgccaa ttaatattat caatttccgc taataacaat
    13561 cccgcgatat agtctctgca tcagatactt aattcggaat atctaacgtg ttttcttatt
    13621 actttcaagg tcttgcactt ggggcggcta tgatcctacc gctcggtcca caaaatgctt
    13681 ttgtgatgaa tcagggcatt cgtcgtcagt accacattat gattgcctta ctttgtgcta
    13741 tcagcgattt ggtcctgatt tgtgcgggga tttttggtgg cagcgcgtta ttgatgcagt
    13801 cgccgtggtt gctggcgctg gtcacctggg gcggcgtagc cttcttgctg tggtatggtt
    13861 ttggcgcttt taaaacagca atgagcagta acattgagtt agccagtgcc gaagtcctga
    13921 aacaaggcag atggaaaatt atcgccacca tgttggcagt gacctggctg aatccgcatg
    13981 tttacctgga tacttttgtt gtgctgggca gccttggcgg gcaacttgat gtggaaccaa
    14041 aacgttggtt tgcgctcggg acaattagcg cctctttcct gtggttcttt ggtctggcta
    14101 ttctcgcagc ctggctggca ccgcgcctgc gcacggcaaa atcacagcgc attatcaatc
    14161 tggtagtggg atgtgttatg tggtttattg ccttgcagct ggcgagagac ggtattgctc
    14221 atgcacaagc cttgttcagt taggcgctat ctgatggaaa aataaaacag aggcgctaag
    14281 cttgcctcca gaggtcctga attttgggca agtcaattaa cacggagaga ctaacgtgaa
    14341 gttcaaagtt atcgccctgg cggcattaat gggtattagc gggatggcag cgcaggctaa
    14401 cgaattgccg gatggaccgc atattgtcac ctccggtacg gcaagcgtgg atgcggtgcc
    14461 agacattgcc actcttgcga ttgaagttaa cgtggccgcg aaggatgccg ctactgccaa
    14521 gaaacaggca gatgagcgcg tcgcacaata catttccttc cttgagctca atcagatcgc
    14581 gaaaaaagat atcagctcag cgaacttacg cactcagcca gattatgatt atcaggatgg
    14641 taaaagtatc ctgaaaggct accgcgcagt gagaacggtg gaagtcacgc tccgtcagtt
    14701 agacaaactg aattccttgc tggacggcgc gctaaaggcg ggtcttaacg aaattcgttc
    14761 tgtgtcgctg ggcgtggcgc agccggatgc ctataaagac aaagcgcgta aggcagcgat
    14821 tgataacgcg attcatcagg cacaggaact ggcgaatggc tttaatcgta aactggggcc
    14881 ggtatatagc gtgcgctacc atgtttccaa ctatcagccc agcccaatgg tgcggatgat
    14941 gaaagctgat gctgcaccgg tgtccgcaca ggaaacttac gagcaggccg ctattcagtt
    15001 tgatgatcag gtcgatgtag tcttccagtt agaacctgtg gatcaacaac ctgctaaaac
    15061 acctgcagca caataatact tgtagcccga cgtattcgtc gggctaatgc ctttacccga
    15121 tattgcctcc tttttctgta attttctgta aaaccatgac gtaatcacct atctttgctc
    15181 gcggtttcat caaggatagg ctgactgaaa cggttaagcg gacaaggatg cgggagaggg
    15241 gggatggaca tttttatttc gaaaaagatg cgcaatttca ttttattagc gcaaaccaat
    15301 aatattgccc gggcggcaga aaaaatccat atgacggctt cgccatttgg caaaagcatt
    15361 gccgcgctgg aagaacaaat tggctatacg ctatttaccc gcaaagataa taatatcagc
    15421 ctcaataaag ccggacagga actgtatcaa aaactgttcc cggtttatca acgactttct
    15481 gcgattgata atgaaatcca taactcagga cgtcgttaac gagaaattgt gataggcata
    15541 gataatactt atccgacaat tatttttgat cagttgatta gtctcggaga taagtacgaa
    15601 ggcgtgacca tccagccagt tgagttcagc gaaaatggcg ttatcgataa tctttttgac
    15661 cgtcagttag attttattat ctccccacag catgtatctg cacgagttca ggaactggaa
    15721 aacctgacta tcagtgaact accaccgctg cgattgggct ttctcgtttc tcgccgttat
    15781 gaagggcgac aggagcaaga gctgcttcag gagctgccct agctacaaat gcgctttcaa
    15841 aaccgggcta acttcgaagc aatgattgat gcgaatatgc gtccttgtgg gatcaatcca
    15901 accattattt atcgtcccta tagttttatg gctaaaatca gcgccgtgga gcggggacat
    15961 tttctgacgg tgatcccgca ttttgcctgg cgactggtga atccggcaac gctgaaatat
    16021 tttgatgcgc cgcacaggcc gatgtatatg caggaatatc tttattcaat cagaaatcat
    16081 cgttataccg ccacgatgct tcagcatatt gctgaagatc gtgacgggac aaaccattaa
    16141 cccagcatcg atccggttgc aattaaatta cggtgtaagt cgaagacgtg gctaagatcg
    16201 tggtgaatat gtccgccgga cgcattttcc agatatcgat gcagataatc ccgatacatg
    16261 ggatgtgcac aatgatcaat ggtggtgcgg ataacgttgt tatacggatc ctgtgcgcca
    16321 aatccactga ccgcttcgct ccataaataa cgtgccgcac gcaacatggc gacgttcata
    16381 aacagatcca tgccaatgcc gaagaaaaac gacaggcgag gggcgaagtc atcaattttc
    16441 agcccggcgg agattgctgc tttgatgtac tcaatcctat cggcgagcgt aaatgctacc
    16501 tgctgcacgc agttggcacc cgcttcaccc atgtggtaac cgctgatact gatggtatta
    16561 aatcgcggca tgttgccgga acaccaggcg atgatgtctg cgataatacg cattgacggt
    16621 tttggtgggt aaatataggt gttgcggcaa agatactctt tgaggatatc gttttgaatg
    16681 gtgccggtca gtttatcgga tgtaacacct tgctcttctg cggcgacgat ataaaacgcc
    16741 agtactggta gcactgcgcc attcatggtc atcgaaaccg acattttatc cagcgggatc
    16801 tggtcgaaca ggacttttat atcttccacg gtgtcgatag cgacgcccgc tttgccgacg
    16861 tcgcccgcca cgcgtgggtt atcggagtcg tagcctcggt gggtggccag gttacggcga
    16921 taaaaagcgt tggactcttt tgctgtcgag aaaccagcat actgacggat ggtccacggt
    16981 tgggcggtat acatagtggc acgcgggcca cgaacgtagg ggggcaaacc aggaagggta
    17041 cccgtcacct ccagattatc gagatcggct tcggtataca gcggcttgat ggcgatccct
    17101 tccgcggttt gctgaaccag cgagtcgaca gttttctccc gacggctcaa ttccttgttg
    17161 gcaagctgtt gccactcctg cacgttagac attatttgct ccgtaaaacg caatcaaaat
    17221 gagggtattt gcgcttacgg tgagcttttt acgtgggttt gtcgccagca aaaaaatgca
    17281 ttcagacgtc gttttttgcc gcctgagatt tgtctatttt gcgatgtgat tcaaggaata
    17341 caaaaagaag tgaggataac gcctgatatg tgctatcagg cgttatttga tggattaatc
    17401 ctgacgaaga actttgtgac cataatcgag caacgcatca gtgactttac gcatcatgcg
    17461 gctttcagga gcaaagcggt gccagtagag catccggcgt tgaaatagcc ctggcgttaa
    17521 gtcaatcagt tcgccgctgg ccagctcttt ctcgatttgc aggtgcggga tcatacagca
    17581 ggtggtgccc tgacgagcaa gttgcacgaa cgcttccgaa gaattaacga tatggcaggg
    17641 tacgctgcca ggaggcagat cgaaattttg ctgcaaaaag gcctggtgca tatcgtcaag
    17701 atggtcaaac gcgaccactg gcgctttcag taatgccgaa cgcgttacgc cgttagggaa
    17761 atatttttcg gcaaatggtt ttgagctgac gaacagatag tcgagcgcac cgagtttatc
    17821 gacaagacaa ctcggcagcg cctgatgttg aatactcact gcgccgacca cttcgccgcg
    17881 acgcagacgt tcctgagtgc gggtttcatc ttctacctgc aagttgaggc ggatgggcga
    17941 atcagccaac acaggagcca gtgccggaag caaccacgtc gccagactgt cggcgttgac
    18001 cgccagtgaa agcagcagcg gagtcgaacc ggtttgttca tcgcccagcc actcttcttc
    18061 cagcagctcc acctggcgta gtagcgccaa cagtttttgc ccttgttccg tcgggcgcgg
    18121 cggtacggta cgcactaaca acggctgccc gaacatattt tccagttgct taatgcgctg
    18181 tgagacggct gattgtgtaa tgcacagctt ttgtgccgcg cgctcaaatc ctcgttcacg
    18241 tatcaccgca tccagtgcct gtaatgttct gtagtccggg cgtttcattg ctgttgtctg
    18301 ctcctggtaa atgctttttc ctgcactatg acacaatttt gtgtcgggtt gcatataccg
    18361 aagccgttgg cgggtaacat ttgtatcagt ggttaacgcg cagcttaaaa gatcagagat
    18421 ttgcgctaat gcatttcgct cagcgagttc gcgccctggt tgtgttgaat ggcgtggcgt
    18481 tattgcctca gtttgcctgt aaacaggggc ttgcgaacgg ggaactggtg cgcctgttcg
    18541 caccgtggag cggcataccc agaccgttgt atgctttatt tgcggggcga aaagggatgc
    18601 ccgccattgc gcgatatttt atggatgagt taaccacgcg gcttgccaac ggggtctgaa
    18661 tcgctttttt tgtatataat gcgtgtgaaa tttcatacca caggcgaaac gatcatgacg
    18721 caggatgaat tgaaaaaagc agtaggatgg gcggcacttc agtatgttca gcccggcacc
    18781 attgttggtg taggtacagg ttccaccgcc gcacacttta ttgacgcact cggtacaatg
    18841 aaaggccaga ttgaaggggc cgtttccagt tcagatgctt ccactgaaaa actgaaaagc
    18901 ctcggcattc acgtttttga tctcaacgaa gtcgacagcc ttggcatcta cgttgatggc
    18961 gcagatgaaa tcaacggcca catgcaaatg atcaaaggcg gcggcgcggc gctgacccgt
    19021 gaaaaaatca ttgcttcggt tgcggaaaaa tttatctgta ttgcagacgc ttccaagcag
    19081 gttgatattc tgggcaaatt cccgctgcca gtagaagtta tcccgatggc acgtagtgca
    19141 gtggcgcgcc agctggtgaa actgggcggt cgtccggaat accgtcaggg cgtagtgacc
    19201 gataacggca acgtgatcct cgacgtccac ggcatggaaa tccttgaccc gatagcgatg
    19261 gaaaacgcca taaatgcgat tcctggcgtg gtgactgttg gtttgtttgc taaccgtggc
    19321 gcggacgttg cgctgattgg cacacctgac ggtgtcaaaa ctattgtgaa atgatctgac
    19381 gggggaacct cccccgttaa aaaaattctc ttcattaaat ttggtgacat gtgtcacgtt
    19441 tttaccaggc aattgtcgat tgctctaaat aaatcctcta aaccagcata ttcatccaag
    19501 aaatactttt gcgtgatatt tcctcaacat cgcgacgcaa acgttcatat tgccgcaata
    19561 ttattttttg atatgttgaa aggcggatgc aaatccgcac acaacatttc aaaagacagg
    19621 attgggtaaa tggcaaaggt atcgctggag aaagacaaga ttaagtttct gctggtagaa
    19681 ggcgtgcacc aaaaggcgct ggaaagcctt cgtgcagctg gttacaccaa catcgaattt
    19741 cacaaaggcg cgctggatga tgaacaatta aaagaatcca tccgcgatgc ccacttcatc
    19801 ggcctgcgat cccgtaccca tctgactgaa gacgtgatca acgccgcaga aaaactggtc
    19861 gctattggct gtttctgtat cggaacaaac caggttgatc tggatgcggc ggcaaagcgc
    19921 gggatcccgg tatttaacgc accgttctca aatacgcgct ctgttgcgga gctggtgatt
    19981 ggcgaactgc tgctgctatt gcgcggcgtg ccggaagcca atgctaaagc gcatcgtggc
    20041 gtgtggaaca aactggcggc gggttctttt gaagcgcgcg gcaaaaagct gggtatcatc
    20101 ggctacggtc atattggtac gcaattgggc attctggctg aatcgctggg aatgtatgtt
    20161 tacttttatg atattgaaaa caaactgccg ctgggcaacg ccactcaggt acagcatctt
    20221 tctgacctgc tgaatatgag cgatgtggtg agtctgcatg taccagagaa tccgtcaacc
    20281 aaaaatatga tgggcgcgaa agagatttcg ctaatgaaac ccggctcgct gctgattaat
    20341 gcttcgcgcg gtactgtggt ggatattcca gcgctgtgtg acgcgctggc gagcaaacat
    20401 ctggcggggg cggcaatcga cgtattcccg acggaaccgg cgaccaatag cgatccattt
    20461 acctctccgc tgtgtgaatt cgacaatgtc cttctgacgc cacacattgg cggttcgact
    20521 caggaagcgc aggagaatat tggcctggaa gttgcgggta aattgatcaa gtattctgac
    20581 aatggttcaa cgctctctgc ggtgaacttc ccggaagtct cgctgccact gcacggtggt
    20641 cgtcgtctga tgcacatcca cgaaaaccgt ccgggtgtgc tgactgcgct caacaaaatt
    20701 tttgccgagc agggcgtcaa catcgccgcg caatatctgc aaacttccgc ccagatgggt
    20761 tatgtagtta ttgatattga agccgacgaa gacgttgccg aaaaagcgct gcaggcaatg
    20821 aaagctattc cgggtaccat tcgcgcccgt ctgctatact aaatcccttt ctctgaaaat
    20881 caacgggcag gtcactgact tgcccgttat tttatccctt ctccacaccg ttgccgcgtt
    20941 gcgcattcta ctttgcgagt ctgctccaga aaataaatca aagtcagatc aatgcgttgt
    21001 gtttatttaa tggggattta cgatggcggg actgtacagg gctgtaacgg taaagccctc
    21061 accgaagcga gggcttgaag gagaagggtt atgatgcgac ttgtcatcat actgattgta
    21121 ctgttactca taagtttcag cgcttattaa cagtcagtca caggggagga gcaatccccc
    21181 cttaccctta ctcactaaat taggttaaag aatcaacgat gtcaatcagg gcgatgcagg
    21241 tgtgtcgccc tcaccactcc cagactttcg acggtgtaac caccgcaggc agtgggatat
    21301 cccactcttc aacggggagt ttttccacca actgacaatc atgcgcataa cccaccggtt
    21361 gcattttata gtgctgccag ttttgtaagg tccgatcata aaaaccaccg cccattccca
    21421 ggcgctgacc gtactcatca aaggcgacca gcggtgtaat caacacgtct aatcgggaaa
    21481 ggggtagcac gtcacgcaca tccagttttg gctcatggat cttcaacttg ttcatcacca
    21541 gttcgctttg tggatggtaa ttcaggaaca gcaaattacc ggcactaaag ggatgcaaaa
    21601 ctggaagata tacgcgctta ccggcgcgcc agagttgttc tatgagtggc tgggtgtcga
    21661 gttcgccatc aaaagagagg aatacagcga ccgtatgtgc catcaccacc gggggataag
    21721 tcatcatccg ggtagcggct tgttgaccca tttcctgctg ttgttccggc gttaacgcac
    21781 gacgacgttg ccgaatcatt ttgcggattt cttgtcggga taatgtcagt gggagttctg
    21841 gtaattgcgt catggctggt gccagataag aagggaatct ccgagatgcc gccgcaggct
    21901 gtaacccttg aacccttggt tcaaggtgaa tgtgtcgtcg cagttttaag gcttctcgga
    21961 cggaccgagc atgctcacca accgcggagc gccacattct tgtggtatga aatatcggct
    22021 caggggactg gcccgcttgc gaacatctca gagaaatttt gtcttcacgg ttactctacc
    22081 acagtaaacc gaaaagtgtc attcaaagtt ttggttagtt ttttcggtga tgcgaccttg
    22141 ttcaagtaac gcttgttcta tggtctgctg cagcatccga atacgctgtt ccatacttgc
    22201 cgcgtagtca cgagtcttcg ctttttcttg cgctaactca tagctgatat tcagtgcggc
    22261 aatgaagacc aactgttcag tatttgtgac tctagtgcgt tctttcagat cttgcaaccg
    22321 ttggttcaga tcgtccgctg cctgattcaa cgcatccctt tggtcaggcg ggcagttcac
    22381 acgcagtgaa cggccaaaaa tttggatatc gacgggttgt gcagacatgc caccttcctg
    22441 ctgattgact gcgctgcctt cgtctttaga cccatggtct gcgaaggggc gacactatag
    22501 ctaccctgat gagaagagac aagccctttt ctggtccacc agggcccaaa gtggtagcat
    22561 atcatgaata ttcctccctt tgacgacgaa tgcttatgtc tatacagaac gaaatgcctg
    22621 gttacaacga aatgaaccag tatctgaacc aacaagggac gggtctgacc cctgctgaga
    22681 tgcatggttt aatcagtggg atgatatgtg gcggtaacga tgacagctca tggctgccgc
    22741 tacttcacga cctgacgaac gaaggcatgg ctttcggtca tgagctggca caggcactgc
    22801 gcaaaatgca ctctgccacc agcgatgccc tgcaggatga cggcttcctt tttcagcttt
    22861 atctacctga tggcgatgat gtcagcgttt tcgatcgggc tgatgcgctg gctggttggg
    22921 tcaatcactt cctgcttggt cttggcgtta cgcaaccgaa gctggacaaa gtgaccggcg
    22981 aaaccggtga agccatcgac gatctgcgta acatcgcgca gttgggttac gacgaagacg
    23041 aagatcagga agagcttgaa atgtcgcttg aagagatcat cgagtacgtc cgtgttgccg
    23101 cgctgttatg ccacgacacc tttactcatc cgcaaccgac cgcgccagaa gtacaaaaac
    23161 cgactctaca ctaaaaacaa aaaacgtaag gagagtgtta tgagtgatat atcccggcaa
    23221 gaatttcagc gtcgccgtca ggccctggta gagcaaatgc aacccggcag cgccgcgctg
    23281 atttttgctg caccagaagt aacacgtagc gccgacagcg aataccccta tcgtcagaac
    23341 agtgacttct ggtacttcac cggctttaac gaaccggaag cggtgctggt gctgattaaa
    23401 agcgatgaca ctcataacca cagcgttttg tttaaccgcg ttcgcgacct gacggcagag
    23461 atctggtttg gtcgtcgctt aggccaggat gccgcgccag agaaactggg cgttgaccgc
    23521 gcactggcat tcagcgaaat caatcaacaa ctttatcaac tacttaatgg tctggatgtg
    23581 gtttaccacg cccagggcga atatgcatat gctgatgaaa tcgtgaacag cgcgcttgag
    23641 aaactgcgta aaggttcgcg gcaaaatctc accgcaccgg caacgatgat cgactggcgt
    23701 cctgttgttc atgaaatgcg cctgttcaaa tcaccagaag agattgccgt acttcgccgc
    23761 gcgggtgaaa tcaccgcact ggcgcataca cgggcgatgg aaaaatgccg tccggggatg
    23821 ttcgagtacc atctggaagg cgaaattcac cacgaattta accgccacgg tgcgcgttac
    23881 ccttcctata acaccattgt tggcagcggt gaaaacggct gcattttgca ttacaccgaa
    23941 aacgagtgtg aactgcgtga cggtgacctg gtgttgattg acgcgggttg tgaatacaaa
    24001 ggttacgctg gcgacattac ccgcaccttc ccggtcaacg gcaaattcac tcaggctcag
    24061 cgtgaaatct atgacattgt gctggagtct cttgaaacca gcctgcgcct gtatcgtccg
    24121 ggaacttcca ttcaggaagt cactggtgaa gtggtgcgca tcatggttag cggtctggta
    24181 aaactcggca tcctgaaagg tgatgttgat gaactgatcg ctcagaacgc ccatcgtcct
    24241 ttctttatgc atggccttag ccactggtta ggactggatg ttcatgacgt tggtgtttat
    24301 ggtcaggatc gctcgcgtat tctggaaccg ggtatggtac tgaccgtaga accaggactg
    24361 tatattgcgc cggatgcaga agtgccagaa cagtatcgcg gtatcggcat tcgtattgaa
    24421 gacgatattg tgattaccga aaccggtaat gaaaacctca ccgccagcgt ggtgaaaaag
    24481 ccggaagaaa tcgaagcgtt gatggcagct gcgagaaagc aatgagcgta atcatcgtcg
    24541 gtggcggcat ggcgggcgcg acgctggcgc tggctatttc ccggttaagt cacggggcgc
    24601 tgccagtaca tttgattgaa gcgaccgcgc cagagtcaca tgcgcatccg ggctttgatg
    24661 gacgagctat tgcgctggcg gcgggtacct gtcagcaact ggcgcgcatc ggcgtctggc
    24721 aatctctggc tgattgcgca actgccatca ccaccgtgca tgttagcgat cgtggtcacg
    24781 ctggatttgt caccctcgcc gcagaagatt accaactggc ggcgctgggg caggttgtcg
    24841 aattgcacaa tgtcgggcaa cggctgtttg cattgctgcg caaagcacct ggcgtaacgc
    24901 tgcattgccc tgatcgcgtg gctaacgttg cccgtactca gagccacgtt gaagtgacgc
    24961 tggagagtgg cgagacgctg acgggccgcg tgctggtagc cgctgatggc acccattcag
    25021 cgttagccac cgcgtgcggt gttgactggc agcaggagcc ttacgaacaa ctggctgtga
    25081 ttgccaacgt tgcgacttcc gttgcgcatg aagggcgcgc ttttgaacgc tttacacaat
    25141 atggcccgct ggcgatgttg ccgatgtctg acggacgctg ttcgctggtc tggtgtcatc
    25201 cactggaacg gcgcgaagag gtgctgtcgt ggagcgacga gaagttctgc cgtgaactcc
    25261 agtcggcctt tggctggcga ctggggcaaa ttacccacgc cggaaaacgt agtgcttatc
    25321 cgctggcgtt aacccgcgcc gccaaaccta ttacccatcg taccgtgctg gtggggaatg
    25381 cggcgcaaac tctgcatccc atcgccgggc aaggatttaa cctcggtatg cgtgatgtga
    25441 tgagtcttgc agaaaccctg actcaggcgc aggaacgcag agaagacatg ggtgattacg
    25501 gcgtattgtg ccgttatcag cagcgtcgac agcgcgatcg cgaagcaacc atcggcgtca
    25561 cggacagcct tgtacatctt tttgccaacc gttggacgcc gctggttgtc gggcgcaaca
    25621 tcgggctgat gacgatggaa ttatttaccc cggcacgcga tgtgctggcg cagcgcactc
    25681 ttggttgggt ggcgcgttga aggcggtttt aaggaataaa caatgcaaag tgttgatgta
    25741 gccattgttg gcggcggcat ggtcgggctg gcggttgcct gcggcttaca gggtatcggc
    25801 ttacgcgttg ccgtactgga gcagcgcgta ccggaacctc tggcggcgga tgcaccacca
    25861 caactgcgcg tttcggctat caatgccgcc agcgaaaaat tactcacccg tcttggcgtc
    25921 tggcaggaca ttctctctcg tagggcctgt tgctatcacg gcatggaagt gtgggacaaa
    25981 gacagctttg gtcacatctc gtttgacgat caaagcatgg gctatagcca tcttgggcat
    26041 atcgttgaaa actcagtgat tcactacgcg ctgtggaaca aagcgctgca gtcgtcagat
    26101 atcactctgt tggcccccgc agaattacag caggtcgcct ggggtgaaaa tgaaaccttc
    26161 ctgacgttga aagatggcag catgttaacg gcgcgtctgg tgattggcgc ggacggcgct
    26221 aattcctggt tgcgcaacaa agccgatatt ccgctgactt tctgggatta tcagcatcac
    26281 gcgctggtgg cgaccattcg cacggaagaa ccgcatgatg cggtggcgcg acaggttttt
    26341 catggcgaag gcattctggc ctttttgccg cttagcgatc cgcatctttg ctcgattgtc
    26401 tggtcactgt cgccagagga agcgcagcgg atgcagcagg caggcgaaga cgaatttaat
    26461 cgcgcgttaa atatcgcttt tgataatcgc ctgggcttat gcaaggttga aagtgagcgc
    26521 ctggtgttcc cgctaacggg gcgttatgcg cgccagtttg ccgcgcaccg tctggcgctg
    26581 gtgggcgacg ccgcgcatac cattcacccg ttggcggggc agggggtaaa tctcggcttt
    26641 atggatgctg cagagctgat tgctgaactg aaacggttgc atcgtcaggg taaagacatc
    26701 gggcagtaca tttacctgcg tcgctatgag cgtagccgca agcacagcgc ggcgctgatg
    26761 ctggctggta tgcagggatt ccgcgatctg ttttccgggg ctaatccggc gaaaaaattg
    26821 ctgcgtgata ttggtctgaa actggctgat acgcttcctg gcgttaagcc acaacttatt
    26881 cgccaggcaa tgggattaaa cgatttgcct gaatggctgc gttaaaaatt tctcttctgc
    26941 tgtttatttg atacccatca cactttcatc tcccggtttt ttcgccggga gattttcctc
    27001 atttgaaata aactaatttc acctgcgatt tcgcattata ttttctaatg ccacgaattt
    27061 ttgatttagt gttttttgac atttttttag ttcttaatgt tgtcttattc aaattaactt
    27121 tctcatctat ttatctttat atagagattt gttcattttt tggtttttta ttctgttacg
    27181 attttggcgt tttttaacca taagctaatg tgatgatcaa ttttacctta tggttaacag
    27241 tctgtttcgg tggtaagttc aggcaaaaga gaacgattgc gttggggacc gggagtggct
    27301 ccgatgctgg gtttcgtggt gataatttcg ccatagaaaa gttgtcagcc ccgcttattc
    27361 aatgaggaca agatggcaca acagactcct ttgtacgaac aacacacgct ttgcggcgct
    27421 cgcatggtgg atttccacgg ctggatgatg ccgctgcatt acggttcgca aatcgacgaa
    27481 catcatgcgg tacgtaccga tgccggaatg tttgatgtgt cacatatgac catcgtcgat
    27541 cttcgcggca gccgcacccg ggagtttcta cgttatctgc tggcgaacga tgtggcgaag
    27601 ctcaccaaaa gcggcaaagc cctttactcg gggatgttga atgcctctgg cggtgtgata
    27661 gatgatctca tcgtctacta ctttactgaa gatttcttcc gcctcgttgt taactccgcc
    27721 acccgcgaaa aagacctctc ctggattacc caacacgctg aacctttcgg catcgaaatt
    27781 actgttcgtg atgacctttc catgatcgcc gtacaagggc cgaatgcgca ggcaaaagct
    27841 gccacactgt ttaatgacgc ccagcgtcag gcggtggaag ggatgaaacc gttctttggc
    27901 gtgcaggcgg gcgatctgtt tattgccacc accggttaca ccggtgaagc gggctacgaa
    27961 attgcgctgc ccaatgaaaa agcggccgat ttctggcgcg cgctggtgga agctggcgtt
    28021 aagccatgtg gcctgggcgc gcgtgacacg ctgcgtctgg aagcgggcat gaatttgtat
    28081 agccaggaga tggacgaaac tatttctcct ttagccgcca atatgggctg gactatcgcc
    28141 tgggaaccgg cagatcgtga ctttatcggt cgtgaagctc tggaagcgca gcgtgaacat
    28201 ggcacagaaa aactggttgg tctggtgatg accgaaaaag gcgtgctgcg taatgaactg
    28261 ccggtacgtt ttactgatgc gcagggcaac cagcatgaag gcattatcac cagcggtact
    28321 ttctccccaa cgctgggtta tagcattgcg ctggcgcgcg tgccggaagg tattggtgaa
    28381 acggcgattg tgcaaattcg caaccgtgaa atgccggtta aagtgacgaa acctgttttt
    28441 gtgcgtaacg gcaaagccgt cgcgtgattt acttttttgg agattgattg atgagcaacg
    28501 taccagcaga actgaaatac agcaaagaac acgaatggtt gcgtaaagaa gccgacggca
    28561 cttacaccgt tggcatcacc gaacacgctc aggagctgtt aggcgatatg gtgtttgttg
    28621 acctgccgga agtgggcgca acggttagcg cgggcgatga ctgcgcggtt gccgaatcgg
    28681 taaaagcggc gtcagatatt tatgcgccag taagcggtga aatcgtggcg gtaaacgatg
    28741 cactgagcga ttctccggaa ctggtcaaca gcgaaccgta tgcaggcggc tggattttca
    28801 aaatcaaagc cagcgatgaa agcgaactgg aatcactgct ggatgcaacc gcatacgaag
    28861 cattgttaga agacgagtaa cggctttatt cctcttctgc gggagaggat cagggtgagg
    28921 aacatttacg cctcaccctc actctcttcg taaggagaga ggttcacaat tcactgcacg
    28981 tttcaggaac catcgctcat gacacagacg ttaagccagc ttgaaaacag cggcgctttt
    29041 attgaacgcc atatcggacc ggacgccgcg caacagcaag aaatgctgaa tgccgttggc
    29101 gcacaatcgt taaacgcgct gaccggccag attgtgccga aagatattca gcttgcgact
    29161 ccgccgcagg ttggcgcacc ggcgaccgaa tacgccgcac tggcagaact caaggctatt
    29221 gccagtcgca ataaacgctt cacgtcttac atcggcatgg gttacaccgc cgtgcagcta
    29281 ccgccggtta tcctgcgtaa catgctggaa aatccgggct ggtataccgc gtatactccg
    29341 tatcaacctg aagtctccca gggccgcctt gaagcactgc tcaacttcca gcaggtaacg
    29401 ctggatttaa ccgggctgga tatggcctct gcttctcttc ttgacgaagc caccgctgcc
    29461 gccgaagcaa tggcgatggc gaaacgcgtc agcaaactga aaaatgccaa ccgcttcttt
    29521 gttgcttctg acgttcatcc gcaaacgctg gatgtggtcc gtactcgtgc cgaaaccttt
    29581 ggttttgaag tgattgtcga tgatgcgcaa aaagtgctcg accatcagga cgtcttcggc
    29641 gcgctgttac agcaggtcgg cactactggt gaaattcacg actacactgc gcttattagc
    29701 gaactgaaat cacgcaaaat tgtggtcagc gttgccgccg atattatggc gctggtgctg
    29761 ttaactgcgc caggtaaaca gggcgcggat attgtttttg gttcggcgca acgctttggc
    29821 gtaccgatgg gctacggtgg cccacacgcg gcattctttg cggcgaaaga cgaatacaaa
    29881 cgctcaatgc cgggccgtat tatcggtgta tcgaaagatg cagctggcaa caccgctctg
    29941 cgcatggcga tgcagactcg tgagcaacat attcgtcgtg aaaaagcgaa ctccaacatt
    30001 tgtacatccc aggtcttgct ggcaaacatt gccagtctgt atgccgttta ccacggtccg
    30061 gttggcctga aacgtatcgc taaccgcatc caccgtctga ccgatatcct ggcggcgggc
    30121 ctgcaacaaa aaggtctgaa gctgcgccat gcgcactatt tcgatacttt gtgtgtggaa
    30181 gtggccgaca aagcgggcgt gctggcgcgt gccgaagcgg ctgaaatcaa cctgcgtagc
    30241 gatattctga acgcggttgg gatcaccctt gatgaaacca ctacgcgcga aaacgtgatg
    30301 cagcttttca gcgtgctgtt gggcgataac cacgggctgg acatcgacac actggacaaa
    30361 gacgtggctc acgacagtcg ctctattcag gctgcgatgc tgcgcgacga cgaaatcctc
    30421 acccatccgg tgtttaatcg ctaccacagc gaaaccgaaa tgatgcgcta tatgcactcg
    30481 ctggagcgta aagatctggc gctgaatcag gcgatgatcc cgctgggttc ctgcaccatg
    30541 aaactgaacg ccgccgccga gatgatcccg atcacctggc cggaatttgc cgaactgcac
    30601 ccgttctgcc cgccggaaca ggctgaaggt tatcagcaga tgatcgcgca gctggctgag
    30661 tggctggtga aactgaccgg ttacgacgcc gtttgtatgc agccgaactc tggcgcacag
    30721 ggcgaatacg cgggcctgct ggcgattcgt cattatcatg aaagccgcaa cgaagggcat
    30781 cgcgatatct gcctgatccc ggcttctgcg cacggcacta acccggcttc cgcgcatatg
    30841 gcaggaatgc aggtggtggt tgtggcgtgt gataaaaacg gcaacatcga tctgactgat
    30901 ctgcgcgcga aagccgaaca ggcgggcgat aacctctcct gtatcatggt gacctatcct
    30961 tccacccacg gcgtgtatga agaaacgatc cgtgaagtgt gtgaagtcgt gcatcagttc
    31021 ggcggtcagg tttaccttga tggcgcgaac atgaacgctc aggttggcat cacctcgccg
    31081 ggctttattg gtgcggacgt ttcccacctt aacctgcata aaactttctg cattccgcat
    31141 ggcggtggtg gtccgggtat gggaccgatc ggtgtgaaag cgcatctggc tccgtttgta
    31201 ccgggtcata gcgtggtgca aatcgaaggc atgttaatcc gtcagggcgc ggtttctgcg
    31261 gcaccgttcg gtagtgcctc tatcctgcca atcagctgga tgtacatccg catgatgggc
    31321 gcagaagggc tgaaaaaagc aagccaggtg gcaattctta acgccaacta tattgccagc
    31381 cgtctgcagg atgccttccc ggtgctgtat accggtcgcg acggtcgcgt ggcgcacgaa
    31441 tgtattctcg atattcgccc gctgaaagaa gaaaccggca tcagcgagct ggatattgcc
    31501 aagcgcctga tcgactacgg tttccacgcg ccgaccatgt cgttcccggt ggcgggtacg
    31561 ctgatggttg aaccgactga atctgaaagc aaagtggaac tggatcgctt tatcgatgcg
    31621 atgctggcta tccgcgcaga aattgaccag gtgaaagccg gtgtctggcc gctggaagat
    31681 aacccgctgg tgaacgcgcc gcacattcag agcgaactgg tcgccgagtg ggcgcatccg
    31741 tacagtcgtg aagttgcagt attcccggca ggtgtggcag acaaatactg gccgaccgtg
    31801 aaacgtctgg atgatgttta cggcgaccgt aacctgttct gctcctgcgt accgattagc
    31861 gaataccagt aatttactga ttcgactatc ttctaaaggc gcttcggcgc ctttttcgct
    31921 tgttaataaa gtgcgctttg tgtgtttcgg ttgaggcgta atataaaata ttgcgagctc
    31981 aatatattaa aagagtgcca ggcctgatga gcggagcaca tcaggcacat cggctaatta
    32041 caaattctcg ccgttgctgg caatcacctc tttgtaccag ttaaagctct tcttacgtga
    32101 acgcgacata tcgccagtac cgtcgtcatg tttattcaca tagataaagc cgtagcgttt
    32161 gctgtactgc ccggtagtga acgacacgca gtcgatgcag ccccacggtg tgtagcccat
    32221 cagatccacg ccatcgtaag tcaccgcttt tttcatctct tcaatatggg cgcgcaggta
    32281 gtcaatgcgg taatcgtcat tgatgctgcc atcatcttcc actttgtcgt aagcgccaaa
    32341 accgttttcg acaataaaca gcggcttctg gtaacgctca tacagctcgc aaagcgcgta
    32401 acgcagacca accggatcaa tctgccagcc ccagtcagac gctttaacat acgggttcgg
    32461 tacgctgcct tcaaaaccag agatcgcatc gccggtgccg ccttcggcct tcaccgcgtt
    32521 ggtcatgtaa tagctgaagc cgagataatc gcaggtgcct tcgcgcagta catccagatc
    32581 gccgtcttcc attttgatgt taaatccgcg gcgttcccac tcgttcaaca cataggacgg
    32641 gtaatagcca cgcaactgca catcggtaaa gacgtaacgt tcgcgcatcg acttctgggc
    32701 aaacatcaca tcgtccgggt tacaggagta gggatagagc ggcaccatcg ccagcataca
    32761 accgactttc atctccgggt tgatgcgatg cgcggctttc accgccaggg cgctggcgac
    32821 aaactggtga tgcagcacct gatacatggt ctcttccggg ttttcatgtt cggtatacac
    32881 cacgccggag cagcagtaac cgaacagcgg tgcacgccag ttacgctggt tgttaatttc
    32941 gttgaaggtc atccagtatt tgactttgtg cttatagcgt tcgaatacca cttccgcgaa
    33001 acggacaaag aaatcaacca ctttacggtt ggtccagcta ccatattgct gcaccagatg
    33061 cagcggcatt tcaaagtggg agagggtgat caccggttcg atgttgtatt tcagcagttc
    33121 atcgatcata tcatcgtaga acttcagccc ttcttcgttt ggctgagctt catcgccttt
    33181 tggaaaaatg cgcgtccagg cgatggaagt acgaaaacat ttgaagccca tttcggcaaa
    33241 tagcttgatg tcctccttgt agtgaccata aaaatcaacg gcttcatggt ttggatagta
    33301 tttgccaggc acaacttctt tggtgatttc gcgcggcacg ccgtgtgcgc caccggtcag
    33361 aacgtcacaa atgctcggcc ctttgccgcc tttgttccag ccgccttcga cctgatgagc
    33421 ggcaactgcg ccgccccata agaaatcttt cggtaaggtg agttttttca ctatcatagg
    33481 ctccagatga gtcaattctt acaggaaata ttaccatgca gccaaacgac atcacttttt
    33541 ttcaacgttt ccaggatgac attctggctg ggcgtaaaac catcaccatc cgcgacgagt
    33601 ctgaatcgca cttcaaaacg ggtgatgtgc ttcgtgtcgg acgttttgaa gatgacggtt
    33661 atttttgcac gattgaagtc accgcaacct caaccgtaac gctggatacg ctgacggaaa
    33721 aacatgcaga gcaggaaaat atgaccctga ctgaactgaa aaaggtcatt gccgacatct
    33781 atcccgacca gacacagttt tatgtgattg aatttaaatg tctttaaatt gaactcacgc
    33841 ctgttagttg aaatttcgca tttaatttca tgatttttcg gagattaatc tcaaatcaga
    33901 atttatttta gctaacaggt gttcactgga actattctca gttacgctgg agaggtatac
    33961 atgtgcgtgt acgtttttcc ggagtaagtt atggttcaga agcccctcat taagcaggga
    34021 tattcgctgg cagaggaaat tgccaacagc gtcagtcacg gcattgggct ggtgtttggt
    34081 atcgttgggc tggtgttgct actggttcag gcggtggatc tcaatgccag cgccacggcg
    34141 ataaccagtt acagcctcta tggcggcagt atgatcctgc tgttcctcgc ttcgacgctc
    34201 tatcacgcca ttcctcatca acgggcaaaa atgtggctga agaaatttga ccactgcgct
    34261 atttatctgt tgattgccgg aacctacacg ccgtttttgc tggtggggct ggattctccg
    34321 ttagcgcgcg ggttgatgat tgttatctgg agcctggcat tgctgggtat tctgtttaaa
    34381 ctgaccatcg cgcaccgatt caaaatttta tctctggtga cctatctggc gatgggctgg
    34441 ctgtcgctgg tggtaattta tgaaatggca gttaagctcg cggcgggcag cgttacctta
    34501 ctggcggtag gcggtgtggt ttattcgctc ggggtgattt tctacgtctg caagcgcatt
    34561 ccatacaatc atgccatctg gcacggcttt gtgctcggcg gtagtgtgtg ccactttctg
    34621 gcgatctatt tgtatattgg gcaggtgtaa ttggcgtgcc tttgtaggcc tgaaaagaca
    34681 caccagtgtc gcatcaggcg ataaatgcct gatgcgatac agagatttac tcttccagcg
    34741 aatatggcag tggctcaata cgcaatgtat tcgcatcgtc acgcacgcgg aagatgctgt
    34801 ccggttccat atcgttattc atgacaacct gcaccacaac ctgaccatct tccagtttga
    34861 ccgcagccag caccgtaccg gtacgacgcc agttctcgcc cattttcagc tctaagtctt
    34921 caccagcttc cggcagtcgg ctggcgctac ccgtcagcaa ccagagcgcg cgtttgttgg
    34981 caccacggaa ttttgctcgc gccaccatct cttgtccggt atagcagcct ttcttaaagc
    35041 tgatgccgcc cagcgcctgg aggttggtcg cctgggggat aaactgcccg ctgttggcgg
    35101 catcaatcac cggaaaaccc gcttcaatgt ttaatgccag ccactgttgg ctattgttca
    35161 gttccgcttc accgcgcagt ttatcggtca gcatattggc agtagcttca tcggttacga
    35221 tcaggaaacg ttctgccggg tgttcaaacc atagcaacgt ggtcgcgcct tctttgacta
    35281 cctgtttttc tctcgaaggt agttcactaa agagatttgc caacgcggtg cgcgcctgaa
    35341 aaccggcaac accaagcagc acacgctcgt cgtctggcgc gatggtcact ttagagaaca
    35401 ccgcatattt tttcagttca gtcagctgcg gttcacgcac gctgcgccgt tcaatccatg
    35461 caaagccatc gccgtcgcgg aacagacgta aattgctcca cattttacct ttggcgtcgc
    35521 aatgggcggc gagcaggtgc tgatcttcag tcatctggct gacatctgct gtcacctggc
    35581 cttgcatata tttttcgctg tccgcgccag taatagtggc aagcgcccag tcatcaagcg
    35641 tcatcagcgt cagtggcaaa cgggcagaag ccgtaggctg acggggagga aaaggtgtaa
    35701 aagccataat agagtcctga gttgcttaac ggcgtattaa tcactaatgg taaaagagct
    35761 atgaggcaat gcaagtgctt tcactgcgcg atctgtgcct tctgcgaggc gacttccaaa
    35821 aaaatgaagc ccttgaattg ttgtgaatta atttcgcgat cgcgattgtg tttactgata
    35881 ttcccgtaaa agaagtcgaa aaacacgtta caatagccgg gtactggatt ttcgtgagac
    35941 aggaagaaga tggacattaa caacaaagcc cgcattcatt gggcatgccg ccgtggtatg
    36001 cgcgaactcg atatttcaat catgccgttt ttcgaacatg agtacgacag cttaagcgat
    36061 gacgaaaaac gcacctttat tcgtctgctg gaatgtgacg atccggacct gtttaactgg
    36121 ctgatgaatc acggtaaacc agccgatgca gaactggaaa tgatggtccg actcatccag
    36181 acacggaacc gggaacgtgg tcctgtggca atctgatttg cgcgtctcct ggcgcgcaca
    36241 gtggctttcc ttgctgattc atgggctggt tgccgctgtt attttactca ttccctggcc
    36301 gctcagttac accccgttat ggatggtgtt actttcgctg gtggtgtttg attgcgttcg
    36361 cagccagcgg cgcattaatg ctcgccaggg ggaaattcgc ttgttgatgg acgggcgttt
    36421 gcgttggcaa gggcaggagt ggagcatcgt caaagcgccg tggatgatta agagcggcat
    36481 gatgctgcgt ttacgttctg acagcggaaa acggcaacat ttatggctgg cagctgacag
    36541 catggacgaa gccgaatggc gggatttacg gcggatattg ttgcaacaag agacgcaaag
    36601 ataaagatga cggcaaagca tatgtgctaa gccgtcagtg acatcaggcg taatgctctg
    36661 ccatttcgtt gaggatttgc tcgcaccagc tttgaatacg ctcgtcgcta aggtcatact
    36721 ggttagtttc atccagcgcc agacccacga acagttgccc gtcagcaatc accggtttcg
    36781 gactggtaaa ttcatatcct tccgttggcc agtagccgac gaacttcacg cctttggtcg
    36841 agagtttgtc atgcagcata ccgagcgcat cgaggaacca ctcgccgtat cccagttgat
    36901 cgccaagccc atacagcgca acaattttac cttcgaggtt caggtcgtcg agctgatccc
    36961 agacggcttc ccagtcttcc tggatttcgc caaaatccca ggtcgggata cccagaatga
    37021 gcacatcgta ctgctccatt aatttcgggg agtcgtcctt gaggttatgt aaggtcacca
    37081 gttctgggcc gataatatcg cggatttttt ctgccgccat ttcggtgtaa caggtgctgg
    37141 aaccgtaaaa aagacccata ttcataacgt aagcttctcg attctgctgt ggcttttgcg
    37201 gctagtgtat cagaatcgct ttagtcacgg cacaataagg cataatggat caaatgagtg
    37261 accataaggg gcgcaagtga aacaggatct ggcacgcatc gagcagtttc ttgatgctct
    37321 gtggctggaa aaaaatctgg ctgaaaatac gttgaacgct taccgtcgcg atctgtcaat
    37381 gatggtggag tggttgcatc accgcgggtt gacgctggcg acggcgcaaa gtgacgattt
    37441 gcaggcatta ctggcagaac ggctggaggg cgggtataaa gccaccagct cagcgcgttt
    37501 gctgagtgca gtgcgccgat tgttccagta tctttatcgc gaaaagtttc gtgaagatga
    37561 tcccagtgcg catctcgctt caccgaaatt gccccagcgt ttgccaaaag atttaagcga
    37621 agcgcaggtc gaacgtttat tacaggcacc attaattgat cagccactgg agctacgcga
    37681 taaagccatg cttgaagtgt tgtatgctac cggactgcgt gtctctgaac tggtcgggct
    37741 gacaatgagt gatatcagcc tgcgtcaggg cgtggtgcgg gtcattggta aaggcaacaa
    37801 agagcgcctg gtgccgttag gtgaagaggc ggtttactgg ctggaaacct atctggaaca
    37861 tgggcgtccg tggctgttga atggtgtgtc aattgacgtg ttgtttccca gccagcgtgc
    37921 gcagcagatg acgcgacaga ccttctggca ccgcattaaa cattatgccg tgctggcggg
    37981 tatcgacagc gaaaagctgt caccgcatgt gttgcgtcac gcttttgcca ctcacttatt
    38041 aaatcatggt gcggatttac gcgtggtgca gatgctactg ggccacagcg atctctccac
    38101 cacgcaaatt tatacgcatg tcgctaccga gcgtctgcga caacttcatc aacagcatca
    38161 cccgcgggcg tgatgtctga aaagaacagg aaaatttatg aagaaaggtt ttatgttatt
    38221 taccttgttg gcagcgtttt caggctttgt tcaggctgat gacgcggcaa ttcaacaaac
    38281 gttagccaaa atgggcatca aaagcagcga tattcagccc gcgcccgtag ctggcatgaa
    38341 gacagttctg actaacagcg gtgtgttgta catcaccgat gatggtaaac atatcattca
    38401 ggggccaatg tatgacgtta gtggcacggc tccggtcaat gtcaccaata agatgctgtt
    38461 aaagcagttg aatgcgcttg aaaaagagat gatcgtttat aaagcgccgc aggaaaaaca
    38521 cgtcatcacc gtgtttactg atattacctg tggttactgc cacaaactgc atgagcaaat
    38581 ggcagactat aacgcgctgg ggatcaccgt gcgttatctt gctttcccgc gccaggggct
    38641 ggacagcgat gcagagaaag aaatgaaagc tatctggtgt gcgaaagata aaaacaaagc
    38701 gtttgatgat gtgatggcag gtaaaagcgt cgcaccagcc agctgcgacg tagatattgc
    38761 cgaccattac gcacttggcg tccagcttgg cgttagcggt actccggcag ttgtgctgag
    38821 caatggcaca cttgttccgg gttaccagcc gccgaaagac atgaaagaat tcctcgacga
    38881 acaccaaaaa atgaccagcg gtaaataatt cgcgtgaaac aacagataca acttcgtcgc
    38941 cgtgaagtcg atgaaacggc cgacttgccc gctgaattgc ctcccttgct gcgccgttta
    39001 tatgccagcc ggggtgtgcg tagcgcgcag gaactggaac gcagtgttaa aggcatgctg
    39061 ccctggcagc aactgagcgg cgtcgaaaag gccgttgaga tcctttacaa cgcttttcgc
    39121 gaaggaacgc ggattattgt ggtcggtgat ttcgacgccg acggtgccac cagcacggct
    39181 ctaagcgtgc tggcgatgcg ctcgcttggt tgcagcaata tcgactacct ggttccaaac
    39241 cgtttcgaag acggttacgg cttaagcccg gaagtagtcg atcaggctca tgcccgtggc
    39301 gcgcagttaa ttgtcacggt ggataacggt atttcctccc atgcgggggt tgaacacgct
    39361 cgttcgttgg gcattccggt tattgttacc gatcaccatt tgccaggcga cacattaccc
    39421 gcagcggaag cgatcattaa ccctaacttg cgcgactgta atttcccgtc gaaatcactg
    39481 gcgggcgttg gcgtggcgtt ttatctgatg ctggcgctgc gcaccttttt gcgcgatcag
    39541 ggctggtttg atgagcgcgg catcgcaatt cctaatctgg cagaactgct ggatctggta
    39601 gcgttgggga cagtggcgga cgtcgtgccg ctggacgcta ataatcgcat tctgacctgg
    39661 caggggatga gtcgcatccg tgccggaaag tgccgtccgg ggattaaagc gttgctggaa
    39721 gtggccaatc gcgatccaca aaaactcgcc gccagcgatt taggttttgc gctggggcca
    39781 cgtctcaatg ctgccgggcg actggacgat atgtccgttg gcgtggcgct gttgctgtgc
    39841 gacaacatcg gcgaagcgcg cgtgctggca aatgaactcg atgcgctaaa ccagacgcga
    39901 aaagagatcg aacagggaat gcaagttgaa gccctgacct tgtgcgagaa actggagcgc
    39961 agccgcgaca cgctacccgg cgggctggca atgtatcacc ccgaatggca tcagggcgtt
    40021 gtcggtattc tggcttcgcg catcaaagag cgttttcatc gtccggttat cgcctttgcg
    40081 ccagctggtg atggtacgct gaaaggttcc ggtcgctcca ttcaggggct gcatatgcgt
    40141 gatgcgctgg agcggctaga cacgctttac cccggcatga tgctcaagtt tggcggtcat
    40201 gcgatggcgg cgggtttgtc gctggaagag gagaaattcg aactctttca acaacggttt
    40261 ggcgaactgg ttactgagtg gctggaccct tcgctattgc aaggcgaagt ggtgtcggac
    40321 ggtccgttaa gtccggccga aatgaccatg gaagtggcgc agctgttgcg cgatgctggc
    40381 ccgtgggggc agatgttccc ggagccgctg tttgatggtc atttccgtct gctgcaacag
    40441 cggctggtgg gcgaacgtca tttgaaagtc atggtcgaac cggtcggcgg cggtccactg
    40501 ctggacggga ttgcttttaa tgtcgatacc gccctctggc cggataacgg cgtgcgcgaa
    40561 gtgcaactgg cttacaagct cgatatcaac gagtttcgcg gcaaccgcag cctgcaaatt
    40621 atcatcgaca atatctggcc aatttagcgt catcttctct ataaaaaaga gcgtggattg
    40681 ggtacaatcc cgctcttatc accgcatttt gactagctca ataaaagaaa tcagaccatg
    40741 tttgaaatta atccggtaaa taatcgcatt caggacctca cggaacgctc cgacgttctt
    40801 agggggtatc tttgactacg acgccaagaa agagcgtctg gaagaagtaa acgccgagct
    40861 ggaacagccg gatgtctgga acgaacccga acgcgcacag gcgctgggta aagagcgttc
    40921 ctccctcgaa gccgttgtcg acaccctcga ccaaatgaaa caggggctgg aagatgtttc
    40981 tggtctgctg gaactggctg tagaagctga cgacgaagaa acctttaacg aagccgttgc
    41041 tgaactcgac gccctggaag aaaaactggc gcagcttgag ttccgccgta tgttctctgg
    41101 cgaatatgac agcgccgact gctacctcga tattcaggcg gggtctggcg gtacggaagc
    41161 acaggactgg gcgagcatgc ttgagcgtat gtatctgcgc tgggctgaat cgcgtggttt
    41221 caaaactgaa atcatcgaag agtcggaagg tgaagtggcg ggtattaaat ccgtgacgat
    41281 caaaatctcc ggcgattacg cttatggctg gctgcgtaca gaaaccggcg ttcaccgcct
    41341 ggtgcgtaag agcccgtttg actccggcgg tcgtcgccac acgtcgttca gctccgcgtt
    41401 tgtttacccg gaagttgatg atgatatcga tatcgaaatc aatccagcgg atctgcgcat
    41461 cgacgtttat cgcgcatccg gcgcgggcgg tcagcacgtt aaccgtaccg aatctgcggt
    41521 gcgtattact cacatcccaa ccgggatcgt gacccaatgc cagaacgacc gttcccagca
    41581 caagaacaaa gaccaggcca tgaagcagat gaaagcgaag ctttatgaac tggagatgca
    41641 gaagaaaaat gccgagaaac aggcgatgga agataacaaa tccgacatcg gctggggcag
    41701 ccagattcgt tcttatgtcc ttgatgactc ccgcattaaa gatctgcgta ccggggtaga
    41761 aactcgcaac acgcaggccg tgctggacgg cagcctggat caatttatcg aagcaagttt
    41821 gaaagcaggg ttatgaggaa ccaacatgtc tgaacaacac gcacagggcg ctgacgcggt
    41881 agtcgatctt aacaatgaac tgaaaacgcg tcgtgagaag ctggcgaacc tgcgtgagca
    41941 ggggattgcc ttcccgaacg atttccgtcg cgatcatacc tctgaccaat tgcacgcaga
    42001 attcgacggt aaagagaacg aagaactgga agcgctgaac atcgaagtcg ccgttgctgg
    42061 ccgcatgatg acccgtcgta ttatgggtaa agcgtctttc gttaccctgc aggacgttgg
    42121 cggtcgcatt cagttgtacg ttgcccgtga cgatctgccg gaaggcgttt acaacgagca
    42181 gttcaaaaaa tgggacctcg gcgatatcct cggcgcgaaa ggtaaactgt tcaaaaccaa
    42241 aaccggcgaa ctgtctatcc actgtaccga gctgcgtctg ctgaccaaag cactgcgtcc
    42301 gctgccggat aaattccacg gcttgcagga tcaggaagcg cgctatcgtc agcgttattt
    42361 ggatctcatc tctaacgatg aatcccgcaa cacctttaaa gtgcgctcgc agatcctctc
    42421 tggtattcgc cagttcatgg tgaaccgcgg ctttatggaa gttgaaacgc cgatgatgca
    42481 ggtgatccct ggcggtgccg ctgcgcgtcc gtttatcact caccataacg cgctggatct
    42541 cgacatgtac ctgcgtatcg cgccggaact gtacctcaag cgtctggtgg tcggtggctt
    42601 cgagcgtgta ttcgaaatca accgtaactt ccgtaacgaa ggtatttccg tacgtcataa
    42661 cccagagttc accatgatgg aactctatat ggcttacgca gattacaaag atctgatcga
    42721 gctgaccgaa tcgctgttcc gtactctggc acaggatatt ctcggtaaga cggaagtgac
    42781 ctacggcgac gtaacgctgg acttcggtaa accgttcgaa aaactgacca tgcgtgaagc
    42841 gatcaagaaa tatcgcccgg aaaccgacat ggcggatctg gacaacttcg actctgcgaa
    42901 agcgattgct gaatctatcg gcatccacgt tgaaaagagc tggggtctgg gccgtatcgt
    42961 taccgagatc ttcgaagaag tggcagaagc tcatctgatc cagccgacct tcattactga
    43021 atatccggca gaagtttctc ctctggcgcg tcgtaacgac gttaacccgg aaatcacaga
    43081 ccgctttgag ttcttcattg gtgggcgtga aatcggtaac ggctttagcg aactgaatga
    43141 cgcggaagat caggcgcagc gcttcctgga tcaggttgcc gcgaaagatg caggtgacga
    43201 cgaagcgatg ttctacgacg aagattatgt caccgcactg gaacatggct taccgccgac
    43261 agccggtctg ggaattggta tcgaccgtat ggtgatgctg ttcaccaaca gccataccat
    43321 ccgcgacgtt attctgttcc cggcgatgcg tccggtaaaa taagcattac gttatgctca
    43381 caaccccggc aaccgtcggg gttttttatt taagttgggt aaatgcagat aatcgttttc
    43441 tggcttcgcg atttgtcgcc tgcatcacca tccacggact gaacgcccac ggcgtagcat
    43501 caataccgcg taaaaccgct gctaaatcac accattgata atccatcact tcatcatcgt
    43561 tgatctgtaa cgcactggtc gtgcgtgcgg caaataccgg acacacttca ttttccacaa
    43621 tgccattcgg atcggtggcg cggtagcgaa agtcaggata gatagattca ggaggcgtaa
    43681 tttctacgcc aagctcataa cggcaacggc ggatcaccgc ctcttcgttg ctttctccca
    43741 gttgtgggtg cccacaaacc gagttagtcc acacgccagg ccatgctttt ttgctaaggg
    43801 cgcggcgggt aactaataat tgccctttgg cattaaacag ccaactggaa aacgcgagat
    43861 gtaagagggt gtctgccgtg tgtgcggcat acttttccag cgtacccgtg ggaactccct
    43921 gtgcattcaa taaaatgacg tgttccgttt gcataatttc tcacatgtaa ttctgatcac
    43981 tcatcattat agataataga agagtgaaat gattaaccaa gtgagcgttt atcgacaacc
    44041 gcccgttttg agcggatgtc gacaggtaaa aaccatttaa aaaagcagca tcatatattt
    44101 gaagcgactt tcaatggcca ttgcaacaca atcagaaatg acaggaatag agagagtaaa
    44161 aagcaacagc agactgaata tagcgcgcat taaaagattc atattattct ccatgctcat
    44221 ttttcttcag cttgcgcatc agaagccaca tacgtactgt cctgactttt aaatctttat
    44281 cagagacgga ttccttcacc aggtcagcat gatgctggta gccattaaag aagacgttca
    44341 gcacaacggc gctaagggtt gcgagcataa tgccgctatg cagcaacggt tgcagtacgg
    44401 ccggtaactt agaaaagaaa tcgtgagaga gcgttggcgt catgccaaca ccgagactga
    44461 tcgccacaat atagaggttg taacggttag tggtgtagtt acagcgcgac agaattcgaa
    44521 tccctgtcgc cagtaccatg ccgaacatca ccagccccgc gccgcccagc acaaattgcg
    44581 gaatggaggc gaccagcacc gccattttgg gcaccatgcc aaacaggatt aatataattc
    44641 ccgaagaaat acacacccag cggctgtgga cgcgcgtcac gctgaccagc ccgacgttct
    44701 gcgaaaatga cgtatgtggg aagctgttaa acgtgcctcc aatcattgtc ccgaccccat
    44761 ctacgcgtaa cccacgaata atgtcctggg aagagagttt gcgaccgact atttcaccca
    44821 gtgccaggaa catccccatt gactcaataa atacgatgat gagtactgcg gtcatggtca
    44881 aaatggaaac gggatcgaaa atcggcatac caaatgacat cggcgtgaca atcgcaaacc
    44941 atgaagcatc atgtagcccg gataaattga cttcattcat catccacgaa agtaaaaagc
    45001 caaatacaat ccccagtaat acggcgacgt tggacataaa tcctttcgca tagcgagtaa
    45061 tgagcaagat aaaaattaag acggcaaagg agatacctaa ataaacggga ttaccatatt
    45121 gcggattccc tttacctccg gcggcccagt caatacccac ctgaatgatg ctaagcccga
    45181 tagaagtaat caccacaccg gtaaccagtg gcgggaataa aggcatcaag cgaccgataa
    45241 gtggcgctaa taatgtggtg ataaaacccg cggcgatagt ggcaccgaat atccccagca
    45301 ggccgatatc cgggttcata ccaatggcta tcattggtgt tacagcggcg aaggtcaccg
    45361 acataatcac cggcaggcgg atccccataa agcggccgat accgatacat tgcaataatg
    45421 tgacgatccc gcagcaaaag agatccgagc taatgagcat cgcaatagct tcttttgata
    45481 ggccgagtcg gtcaccaatc ataagaggaa cagcgactgc acctgcgtac atgacaagga
    45541 cgtgttgcag accgagtatg atcagctttc ctggtgataa tatgcggtca acctcatcag
    45601 ttgggcggtc ttgcccagaa gatgagggaa gttgggaatc tatggcgctc atcagtgttt
    45661 ctcctttcgc ccgccagagt aaaaagcaac cgtttatgtt catgaaactg tctaaacaca
    45721 tgctcgtgga gtgccagttt ttgcgaggaa ggggagttag agacaggaat tgcggaggca
    45781 atcacataat cgtggttaaa ccacgaaaat gagaagagaa cctgacaatg gaattatctg
    45841 taattttctc atattgatat ttcattaatc attctggcat gtcgcactct cgcatttaat
    45901 cgtttttatc tggatagcat tcttttgatc ggcaatgttg aaataatgaa agcggcatag
    45961 attgaggggc aataatttga actcagttgc aaaattataa ttaaaacggt catgctacct
    46021 aatatatgcc cgtttattgc atcgcgaaat ttgagaagac ataactcatt aaatgaaagg
    46081 gatgcaaatg aataagttta tcgctgctga agctgcggaa tgtataggct gccatgcttg
    46141 tgaaattgcc tgtgcggtgg cacataatca agaaaactgg ccgctgagtc acagtgactt
    46201 tcgaccgcgt atccacgttg tagggaaagg ccaggctgcg aatccggtgg cctgccatca
    46261 ctgcaacaat gccccttgcg ttacggcttg tccggttaat gctctgactt tccagtccga
    46321 tagcgtacaa ctggacgagc aaaaatgtat tggttgtaaa agatgcgcaa tcgcttgccc
    46381 ctttggcgtc gttgagatgg tcgatacgat tgcacagaaa tgcgaccttt gtaaccagcg
    46441 cagttccggc acgcaagcct gtattgacgt ctgcccaaca caggcgttac ggctgatgga
    46501 cgataaaggg ttgcagcaga taaaggtggc ccgccagcgc aaaacggcag caggaaaagc
    46561 gtcatcagac gctcagccat ctcgcagtgc agcgttgctc cccgttaact cgcgtaaagg
    46621 cgcagataaa atttcagcga gtgaacggaa aacccacttt ggcgaaatct attgcgggct
    46681 ggatccacaa caagcgactt atgagagtga ccgctgtgtt tattgtgccg aaaaagctaa
    46741 ctgcaactgg cattgtccgc tgcataacgc tattccggat tacatccgtc tggtacagga
    46801 aggaaagatt attgaagcgg cagaactttg ccaccagacc agttccttac ccgaaatctg
    46861 cggcagggta tgtccacagg accgtctttg tgaaggtgca tgtactttga aagatcactc
    46921 tggcgcagtc tctatcggta atctggaacg ctacatcacc gatactgcgc tggcgatggg
    46981 ctggcgtccc gatgtcagca aagttgttcc ccgtagcgaa aaagtggcgg tgattggcgc
    47041 tggacctgca ggattagggt gtgctgatat tctggcgcgc gcgggagttc aggttgatgt
    47101 ctttgatcgc catccagaaa ttggcggtat gctgactttt ggcattcctc ctttcaaact
    47161 cgataaaacg gtattaagcc agcggcgaga gatattcacc gcaatgggaa tcgatttcca
    47221 tctcaactgt gaaattggcc gcgatatctc tttcaacgaa ttaacggcgg aatatgatgc
    47281 tgttttcctc ggcgtgggga cttacgggat gatgcgagca gatctgccgc atgaagatgc
    47341 gcctggtgtc attcaggcgt taccgttcct gaccgcccat acccgccagc tcatgggatt
    47401 gccggagtct gcagagtatc cgctgacgga tgtggaaggt aagcgagttg tggtattggg
    47461 cggtggcgat acgacaatgg attgtttgcg gacttccatc cgccttaatg ctgccagcgt
    47521 gacctgtgcg tatcgtcgtg atgaagtcag tatgccgggt tcgcgcaaag aggtggtcaa
    47581 tgcccgcgag gaaggtgttg agtttcagtt caatgttcag ccgcaatata tcgcttgtga
    47641 tgaagatgga cgcttaacgg cggtgggcct gattcgtacc gctatgggtg agccggggcc
    47701 ggatggccgc cgtcgtcctc gtccggttgc gggttcagag tttgaattgc ccgccgatgt
    47761 tctcattatg gcctttggtt tccaggcaca taccatgccg tggttgcagg gcagcggaat
    47821 taaactcgat aaatggggcc tgattcaaac cggcgacgtc gggtatttac ccacccagac
    47881 gcatctgaaa aaagtctttg ctggtggtga tgcagttcat ggcgcagatc tggttgtcac
    47941 tgcaatggcc gcaggaaggc aggcggcgcg cgatatgtta actctgtttg atacgaaggc
    48001 atcgtgatga aatcgttaat tatcgttaat ccggctgact gtattggctg ccgtacttgt
    48061 gaagtggcct gtgtggtcgc tcacccttca gaacaggagt tgaatgccga tatcttttta
    48121 ccccggctga aggtacaacg gctggatagc atcagtgcgc cggtgatgtg ccatcagtgt
    48181 gaaaacgccc cttgtgttgg cgcttgtccc gtgggggcgc tgacgatggg cgagcaggtg
    48241 gtgcaggcaa attctgcccg ttgtattggc tgtcagagtt gcgtcagtgc gtgcccgttt
    48301 ggaatgatca ccattcagtc attgccgggg gatacccggc aacaaatcgt gaaatgcgat
    48361 ctctgtgaac agcgggaaga ggggccagcc tgcgttgaat cttgcccgac acaggcgctg
    48421 cagttgctga ctgaaagaga actcaggcga gtccgccagc agcgtattgt tgccagcagt
    48481 gagaatcctc tgtgaaagaa atctccgcgc tgaaaggcgc ggagaatcta ttagattgcc
    48541 caaccacccg cgtaaaacgc gaccagtgcg gcagtaatga tcaccgtacc aatattcagc
    48601 ttttgccatt cgcgcgcaaa gacgcgaccc accaccagtg ttacaaagcc cagcataata
    48661 ccggtaacga tattacaagt cagaacgatg aacacggcac acaccaggcc agccattgcg
    48721 tcaataaaat cgttgaaatc cagcttcgag acgttgctta acatcagcaa acccacgtac
    48781 atcagtgcgg gagctgtggc ataaccgggg atcagaaacg ataacggtga taaaaacaga
    48841 atcatcagga acaacacacc aaccacggtt gcggttaaac cggttttccc cccggcggcg
    48901 gttcctgccg ctgattcgat ataaaccgcc gcgggcgctg cgcccaccag gccggagaat
    48961 attgaactta ctgagtcact ggtcagggct ttgccgccgt tgatgatctg gttgtcttta
    49021 tccaacaaat tcgcctgacc ggcgacggca cggatggtgc cagtggcgtc gaacactgcg
    49081 gtcatcacca atgccagtac actcggaagt acagttggct ggagtgcgcc cataatatcg
    49141 aggctgaaaa tcagagactt accatcttcg ccagtcaggc ttggcatcgc caccagaccg
    49201 tggtacttca ccgctgggtc aaagattaag ccgatgatcg aaattgcaat aatcaccaac
    49261 aagatcccgc cgggtacgcg gcacttttcc agaccgaaga tgaccgccag ccccagtaag
    49321 ctcatcatca ccgggaagga ggtaaaggca ccgagcgcca ctggcaagcc ttcaatcggg
    49381 ttttttataa ccattcccac accgttagca gcaatcagca gcagaaacag gccgataccg
    49441 atacctgtac cgtgagcgat ccccatcggc aaattacgta agatccaggt acgcacaccg
    49501 gttacggaaa tagcggtgaa gatgacgccc atcagaaaga ctgcgcccag tgcgacagga
    49561 acgctaattt gttgcccgag taccagactg aatgcggtaa acgccgtcaa ggaaatagcg
    49621 caaccaatcg ccattggcaa attggcccat aaccccatca gcaacgagcc gaagcccgcg
    49681 accagacagg tggcaacaaa cacagctgcg ggaggaaaac ctgctttgcc cagcattccc
    49741 ggaacgacga taacggaata aaccatggcc agaaaggtcg ttaagccagc cagtacttcc
    49801 tgacgaacgg tactgccacg agcggtaatt ttaaaataat tatccagcgc gccctgtggc
    49861 tttggtgcgt ccggtgtttg taggatgtct ccagacataa tgatgtcctc acgaggatgt
    49921 taaagtttta ttattagttg cgttcgtaca ccagacgacc atcaacgtag gtgcggtaga
    49981 tcgaacggtc atcgcccaac gtcatcatca cgaacaattt gtcgactaaa gaaacagagt
    50041 tgtcatagcg cagctgctgt agcggagtgg cagtgggttc catcaccacg aaatcagcct
    50101 ctttgccagg taaaaagttg ccaatcaaat cgtcaaggcc cagagatttc gctccgccga
    50161 gcgtggccag gtaaaacgct tcatatgccg agaggcgata gccttgtaat tgcaatacct
    50221 tgtaggcttc gttcagcgtt tgcagcatgt taaaagttgt tccggcaccg atatccgttc
    50281 ccatgcccac tttgactttc ttctgccatg cttttttcaa gttgaataag ccgctgccga
    50341 ggtaaaggtt ggaggtcgga cagaaagcaa tgctggattt ggtttcgctg agacgatccc
    50401 actctttttc ttcgagatgg acgcagtgag caaagacgca gtttttaccg gtcaggccgt
    50461 actgatggta aacatcaaga taaccatcat ggtcaggata aagcgatttc acccaggcaa
    50521 tttcatcttt gttttcacag agatgggtat gtacccatgt atccggatat tcttctttca
    50581 ggcgttgcgc catcgccatc tgttcaggag atgaggtagg ggcgaagcgt ggcgtaatcg
    50641 catacaacag acgaccattt ttgtgccagc gttcaatcag ttctttgctt tggtgatagc
    50701 tgctttcggc agtgtcgagc agataatccg gtgcgtttcg gtccatcatc actttaccgg
    50761 caatcatacg catattgata tgactggcgg cttcaaacag cgcatcaacg gattgtggat
    50821 gaacagtgcc aaacaccagc gccgtggtgg ttccgttacg taaaagctgc ttgatgaaga
    50881 acgccgacat ctcgcgggcg tactctaaat cctcataacg acgttcagta gggaaggtgt
    50941 gtttattcaa ccactccagc aattgttcac cataggcccc caccatttca ctttgcggat
    51001 aatggatatg tgtatcgata aagcccggta ctatcagttt gccgcgatag tcgcgcacgc
    51061 gaatggtgtc aggaatttga tgctttccgt cttcccattc gccaaaccat tccacttttc
    51121 cctgtttaat gagtaataaa ccatcctcaa taaaccgcag cgcagaggca atttcttccg
    51181 ggttatcgac cgtacgggtg acatcaataa aactgcctcg taccgctttt aacgtgtgtt
    51241 ctcctgacat cattgactcc tttactgtta atccatctct tccgctgagg taataccagg
    51301 cagaacgttt tcctgtcggt agccaccagg gaggataata tttaataaaa tcgcagttaa
    51361 cccgccagca caaatagggt tttcaactaa tacataaata gaggctggca atattttaaa
    51421 aatttcggga tcgtaggaga taccaagccc taaacctaaa gaagtggcaa caataagcgt
    51481 ttcacggcgc tttaaaccgt tggtgatgat gatgcgaatc cctgcgatgg caatcatgga
    51541 aaacatcaac gtcattgcgc ctcccagaac tgctgaggga atggtcgtga agaagccgcc
    51601 aatcatcgga aataagccga ggataaccag cattaccgcg atggttcgcc cgacataacg
    51661 tgaagcgacg ccagtcatct gaataacccc attattttgc gcaaacgtgg ttaatggtaa
    51721 tgaaccgaca gcggaggcga taacagaaac cagaccatct gccagcacgc cgcctttcag
    51781 tcgggactga tactcttccc cctgaatggg acggcgggaa accattgccg tggcggtgat
    51841 atcgccgaca gcttccagca cgctaagcag ataaatcgtg ccaaccacca ggaactgatg
    51901 gaagctaaaa ctaaagccgt atttgaacgg atgcgggatg gtgattaacg gcaaattgcg
    51961 catactgctg aaatccacca tgcccaggca taacgatgcg atatagccga cacatagccc
    52021 aatggcgatc cctcccatgc gtagcaacgg actgcgacag cagttaaagc cgatcaccac
    52081 aatcaaaacc aataaaccaa cgccgagatg ttcgtaattg ccgaacgtac cgctgctttt
    52141 ggctgcaaat cctccaccaa aatcaataat gccgacttta atcaggctta agccgatcat
    52201 cagcaccaca atgccgctga cggtaggcgt aataacccga cgtaaatagg gcaggataaa
    52261 agaagagccg acaaccagaa atgcgccaac gaaggagacg ccgaggagcg acgacatgat
    52321 taactcttcg tgaaaaccgt cgcttttcat gctgctgccc agcgcaatca tgaccgtaac
    52381 aaatgaaaaa ttgactgact gaattgaaag taaaccagaa ccgacgatgc cgtagcggtt
    52441 tacttgtaac caggtaccaa taccagaggc gatcatcgcc atagaaacaa gataggcagt
    52501 tgtttcagcg gaaagctgta aggccgcacc cacgattaac gcgggggtta ccatcggaac
    52561 gaaaattgcc aacagatggg taatggcacc tacgagagcc tgatgaaagg gagggcgatc
    52621 ctccagttca aatataaggt cagaacctgc atggtttata tcagacatcc cttcactcct
    52681 tttaaagtaa atttgatcat ctgaattagt aaaataaatt cccacgaatt tggggcgcag
    52741 gacgccttga gaacggctta tctcattttc gcagtcacta tttagtcatc gttcaaacag
    52801 agaaacaggc cgccgaagcg gccatttatt acttatattt tttccagcgc ggtgagtatt
    52861 ttctccggtg tgaaatgcca ttcgcgtaac cagatgccgc aggcatcgtg aattgcggta
    52921 gcaatcgccg gagctgcgcc atttacaccg atttccgaga tcgatttcgc cccgaatggg
    52981 ccgactttat cgtcgctcgg caccagcaca gcgcggaaat cacgcggaat gtcaccaatt
    53041 ttcggtgcgc cgtaactgcg taaatcacgc gttaacgggt gaccttcggc gtcataaatg
    53101 atctcttcgc tcatactgtg gccgatagca cgcagggtgg caccgtagat ttgtcccaac
    53161 gctaactctg gattgaccgg tgtaccgcag tccagcaagg cgtagaattt atccaggcgg
    53221 atttcacccg tacgcgtgtt gacggcaact tcagcgaagt ttgcgccata cgggaaggcg
    53281 aaatcaggtg tgatataact gccagttccc accagtgaac caaagccggt gccggtttcg
    53341 cctttatggg ctatctctcc gaaactaact tcgcctttct tgccgcgaac gacgcccggc
    53401 gttgctagtt gaacatctgc cactggctca cccaatattt gcgcgccgtg gaacaggatt
    53461 ttctcccgca gattttccgc tgccaaacgc gcagcgttac ccgagaagca agtaccggac
    53521 gaggcatatg cgcctttatc aaacagtgca tgatcggtat caccagagat aacatgcacg
    53581 tcctgcggtg ggcagtgcag cacttctgct gccagtttgg tcaccacagt atccagacca
    53641 gtaccaatat ccgcaccacc ggaatgaacg ataaaggtgc catccgattc cagtttgatc
    53701 atgcagttag cctgatcgat atccgggata cccgatttct gcatgataat ggcgacgccg
    53761 cgaccgatgt gccagtcacc attttgcggt tttggtgaag accattggat catctcgcga
    53821 ccctgacgca ggatctcttc cagtgcgcag ctggcggcgg aaggaacgga ggtcggcgct
    53881 ttaccttcac cgattgcacc gagaattttc agctcttgcc cttcgtgtac ccggttacgt
    53941 tcgataattt ccagttggtc gatctgtaac tgttcagcca gttccgctaa tgccatggtg
    54001 atagcgaagt tacctttcgg tgcgccataa ccctgataag caccatttgg gcaaatgttg
    54061 ctgtagtagg tggtgacctg aaaatcgacg ttatcgcatg gatataacgg cagcgacagc
    54121 gccggtccgt tacacggtac ggtgagtgag tggttaccgt aaggacccgt gttggcgcgg
    54181 aaatccatct tcactgccgt caggcgacca tcttttttcg cgcccagttt gacggtgact
    54241 ttcgcgacgt gacgagaggt gttagcaata aactcttctt cacgggtgta gcggaaaagt
    54301 accggacgcc cggtcacgca ggttgcccag gcgcacactt cttccagcag gatgtcctgt
    54361 ttggaaccaa aaccgccgcc aactcgctct ttaatgacat gaactttatg ctgtttcatg
    54421 cccacgaggc gcgcgacctg gcggcgtaag tgccatggta cctgggtgga ggcgtggatc
    54481 accagacgat cgccgtccat acgggtaaag cagatatgtg tttcagtcgg gcactgctgt
    54541 gcctgcgttg aattataggt tcgctcaatg atcacatcgg catcggcaaa gcctttgtcc
    54601 atatcgccaa tatgaccatg aatactggcg gcgatatttt tgcgtgggcg agaaccgatc
    54661 gggaagttga tgatcatatg ctcgccgcgc tgggctgcat ggctgttatc atcttccaga
    54721 gtatctggcg caccagcaac atacaccacc ggttcatcgt gcacgacagg cgcatcttcc
    54781 gccattgcct cgtcaatcga cattaccggc ttaagcactt catattcaac gtcgatgagc
    54841 ttcagtgctt cgagcgcaat gtcttcactt tcggctacta ccgcagcaac gcgatcgccg
    54901 acgtgacgca ttttcttgcc gaacattcgg cggtcaagcg gtgacggttc cggtgcgctc
    54961 tgaccacccg gggtatagta aatatccggg caattcaggt gagtaataac gtgaacgacg
    55021 cccggtaagg cttcagcttt gctgacatcc agatgagtaa tcagtgcgtg agcgtgtggg
    55081 ctacgtaaca ttttaatgac gcaggcgtca gccgttacgc gatcttcaac atagcagggt
    55141 ttcgcctgca ccattttcgc ggcatcagtt ttaggataat gcttgccaat gacttcaagg
    55201 tcgtcacgga aagtcggagc gatatcaatg gtggcctgcg gattattttt acgtgcaacc
    55261 gccagttcaa tgacctgata gtattgctgc cagccagcat cgcggctaaa cagacctgag
    55321 agtgcgtcgt cgatctcttc gcgggtaggt gcgtcgatgc gatcgagaag atcggtgata
    55381 atcagagccg cagctggatc gttataacca gactgcacca cgccaacatc aaccatggcc
    55441 tgttgaacca gacttaactc attccatttg cccagagatt ctgcggtacg aatatctgcc
    55501 ttctctaact gtgcggcgat aagcaaggac gcgttaacga tattaccgtt aaagataatt
    55561 gcgtcagaac cggcaaaccc aaagccatca tcactgttgc gtacagagtg cattcccatg
    55621 ttaaacaaca gcttttgcac gttttcgcct ggattaacgg ttagctcctg aggcgcgcca
    55681 tttaaagtaa agtggatgat catacggctt cctccccagc ctgttggcag tcggcataca
    55741 ggtcggctac cagaactccc gtgatatagc gtttataggc cacgctgccc cgcaaatctt
    55801 cctgcgggaa aatggcgttg gcgacagcct gttccagtgc attgccttcc agattttgag
    55861 tttcaacatc atgcagacgc agtgctttac tggcgacgcc atccagcgca attcgcatac
    55921 cgtcgtggtc tgttattgca acggctgccg tcacgacggt taaacctgcc tgagaacggc
    55981 taattttgcg agtcgcacag gtgcgatacg gatctttaat gataatttcg gttaacaggc
    56041 gatcgcatgg gcaggccagg tagtcctcga ttgacagcgt ttcgccgttg ccaaaaacca
    56101 gttcagcatc cagtgccagc aggacgggaa gcagcactga ctcttcttgc cgggcggcaa
    56161 tttcaccacc aatggtcgac tgattacgaa catggcgaga gtagacaaaa ccgagagctt
    56221 cccgcagtgc tgcaggaata aatcgcgcat cacgcagtgg ctgcaagcga gacattgcgc
    56281 caattcgtag tgcaccgtta tcccagtcaa tccagtccag ctccagatcc tgcaaggaaa
    56341 tggcaatctt tttatcggta cgggttggtg tagcgttgag tttgctgccc ccggcgaacc
    56401 agacggcttc atcctggtag cggcgcttca gttccagcgc ctgttcgaca gagtcgggtc
    56461 tgaaaaattg ttcaatcatc gtctttcctt aatttcccct cttctctgaa agaagagggg
    56521 agctgttatt tatgccagcg catccatccg acgccacata ctggcagcgg cttttctggc
    56581 ttgcgcataa atggaatcgc aatcgaagtt aaactgacgg tcttcataga ccatcacacc
    56641 attgaccatc acgctgtgaa cgctacctga gcccataccg aaagcgatat gcccggcgat
    56701 attgtctgcc agcagcggcg tcggcgagtt gtaatcgcaa atggttaaat cggctttgta
    56761 accggcttcc agaagcccaa atttcgcgcc aaagttgcgg ctcatcagtt cgttgccgtt
    56821 agccagtgct ttggcaaaac tgtcaggcca cagcgggcca cccgcatcgc gatgtttaaa
    56881 gaaggcaaat ttcatctctt caaacatgtc cgaaccaatg ccgtccgttc ccaacgccag
    56941 attgcggatg tcgctaaggt gatggttgta gccgacatgg ttgttcatgt ttgaacgggc
    57001 gttatgcacc aggaacgcat cgcgctgatt gagtaggacg atgtcatctt tcgacaggta
    57061 cagcccatga gcgaccagcg ttttgctgtc gatgagatcg aattgcgcaa gtcgtgccag
    57121 caggtctttg ccgtaccaat ggtgactgta ggaaacgtcg taaaggtctt ccgcaacgtg
    57181 aatatgcaaa ccacgacctg tgcttttcac ggcttcacgc agcatctcca gaccggcatc
    57241 cggcacggta aacggcgcgt gagcgccgat atgtgcttcc accagatacg gctcggttgc
    57301 tgctttcttc gcctcatcaa tctgacgggt gaagcggatg ttttcttcta caccttcctg
    57361 caactctttg atgccgttgt tacggtcagt agtttcaaaa caggtcatcg cgcgcaggcc
    57421 aacttttaaa aatgcgttgc gcaatgtgga gagcgacccg tcgatatacg ccggagaggc
    57481 atggtgatcg ataaccgatg tacatccgct cttaatcgct tccagggaac aaatcagtcc
    57541 gctgtaatag agcgactctt catcaagagc gcgatcgagc cgccaccaga gatttttcag
    57601 cgttgagatg aaatccgggc agggggcgat gtttgccata attccgcggg aaagccccga
    57661 gtaaaaatgg ttgtgcgagc agacaattcc cggcatcaca atccgaccat gcatctcttt
    57721 gtagctggca tcggggtagc gttgcgtcag ggcatcgccg atagcgacaa tcacatcatt
    57781 ttcgatggcg atatcaacgc cttcctgcac tttcgccggg tgtaactgca ctgcggtgac
    57841 attcttcaga atcaacatga ttacacctcc acgcggccca gcagataatg atgatgctgg
    57901 tggacatggc taatgatgcg gcacatatcg ttcagctccg gtggtacgtt gttgaactga
    57961 ccttcgctgt cgatgtttaa cacccagctt tggttattca gacgtacgcg tacccggcaa
    58021 tcttccacaa ggaagcctgg gttactgctg ttatcaaagt cttgcgacag gctgaagacg
    58081 gtgattttgt ctttgtacgg tttaccgttc cacgggcaga attgggcgca gttgccgcat
    58141 tcgttgcagt aggcatcgag atgcagcgtc tggaaacggt tctggaagcc aggaaccgca
    58201 atggatacgt tggcgcggtt cgggcagaca tccacacact tgctgcaaac gtagttacat
    58261 tcaaggcagc gtgcggcttc ctgtgcgaca aacgcgtcac gatcgtcact gttcaccaga
    58321 gtgacagaga tatcgccttt acgttgatag atttccgccg gatttacgtt gttccagtat
    58381 ttatcgttct ggtgggaacg gatattttcc cgactaagga tggtatcggt cgcccgacgc
    58441 gcggttccga cagcagcgac aatggaggat ggtccgcgct gtacgtcgcc gatcataaag
    58501 acgtcagtca gacgcgtttc gccattatgg tcgacgtctg gccagccgtt tttgtccagc
    58561 ggcacgccca tcgcattcag ggcttcagta tcctgctgtt caccaatggc ggtgatcaga
    58621 ctgtccacat gcagtgttac tgtttcgttg gtttcaaccg gacggcgacg acctttctca
    58681 tcaggttcgc caagcgacat aacgcgcaag gttaaggtgc catcagcatc gaaacgttcc
    58741 ggattattca gaaaacggaa ctccacgccg tcgtgcaacg cttcttcata ctcttcgcgc
    58801 catgcgggca tttcttgcag tgaacgacgg taaacgaccg ttgctttttc tacgcctgga
    58861 acgcgtaacg ccgcacgagc gcagtccatt gcggtgttac ccgccccgac aacgaccaca
    58921 tgtttgccca gcttgagcgc ggtgcccttg ttgtattcac gcaggaaagg gagtgatttc
    58981 cagacatttt ggttgtcgcc cgccagtttc acaccgctat ttttatcagt gccggtggca
    59041 atcagaacat agtggaagcc ctgatttttt aactgttcaa cggtcaaatc gggtgagcaa
    59101 ccgtactcaa atttcacgcc gtgagcggca acaaaatcga tatcgtgctg aattaactct
    59161 gcaggaatac ggaactgagg aatgatattt ttcaccacgc cgcccgcatt ggcttcgcgt
    59221 tcaaacagcg tgaccggatg gcccgctctg gcaaggaagt aacctgcggc cagacccgcc
    59281 ggacctgcac caatcacggc taccggatgg cgtgaaccgg aaccggctgg tttgtgccag
    59341 cgttgcttat attcatccca acctttttcc agggcgactt ttttcagttc gcggatattc
    59401 agcgcactgt cgtaatccag gcgggtacag ttgtattggc actggtgatc gcaaatatga
    59461 ccggtaatgg cgggcagggc gttgcgttga tagatgagtt ccagcgcgtc ggcatagcgg
    59521 tgttcgccaa gcagacggat gtattccgga atatcttgct tgatagcgca ggcagtaaca
    59581 cagggggcaa cgtagcaatc ggtcagcggc aggtcttcag ccacttcaat acgctcttct
    59641 ggcttccagt gtttctgggt gtattccatg gttaacgcgt ctgctgccag tctgttcagt
    59701 cgttcgacgt caacgtggtt aagctcccag gcgtcggagc cttccagctc gcgcatgcag
    59761 gcacttaagc gcagatagcc gccaggtttc agcaggtcgg ttgccatagt aatagggcga
    59821 ataccagtat caaaaatatc gcggatagtc agctgactgg caccaccgga ataagaaatg
    59881 ggcagtttgc cgtcaaaggc gcgagagaga actgctgcaa cgttgatgga gagcgggaac
    59941 agcgcacggc ctgacatata catctcttca ccgggcagtg cgcctttatt gttgatggtg
    60001 ccgagagtgt tagtcagttt tacgccaaag ccgagtgatt tttcttttgc cagtgccatc
    60061 aggcgttcca gcatttccag tgcttgcgtc agcttgaggt cgtgatcaaa tgactcttct
    60121 tttaagccga tgtaaccgaa accgcagaca tcgaggatct cacgaacacg cgcgtacccc
    60181 agtaaggtcg ggttgagttt cacaaaggtg ttgagtcctt tttcttccag catgtagcgg
    60241 caaatggctt cgatttcatg cggaggacag ccgtgcatgg tggagagggt aacaccttgt
    60301 accatgctgg tggggatgcg agcgggtaag gcttgcaagc tttcgcgttt ttcctgcaat
    60361 ccgtggcggg ctaaaaatgc ctcatcctgg agtagcttat taagtgcatc gcggtattga
    60421 gcgaatttcg gatggtcaga tgcgtccatc atattgtcga tgaactgctg catcggcggt
    60481 tgcttaatac cttcgaggtt gtaaccgacg ctcatattaa agatgaacga tttaccggaa
    60541 tcagaaggct ggaacatcgc ttcgagaagg tgcagggcaa accaggcttt gaggtattca
    60601 tcccaggctt taagcagggt aaattcggta gaccattcgg tgttaaagca ctcgtcttcg
    60661 gcatcgatac agggcttttc cagctccaga cggtcaagaa tttggacggt ttttagttcg
    60721 atgaagcgtc cgccagtcag ccaggaagtg acaatatttt gcgcgagttg cgtgtgcggg
    60781 ccagcggcag ggccgacggg agtggcacag gtttcaccga agacgctaac agttttactt
    60841 tttacgggtg agtaaaactg ttgctcggga ataccaaaga ttgagcgttg ttgttggtat
    60901 tcatcaaata tgcgcgtcaa aagttcctca aacggaatgg gacgcataat atcccccata
    60961 accctctcct tagcttatac agatatcatt gagtgaccgg tgttgagaaa tccggtggtt
    61021 tagggggata gagcaacaat cgcaccactc ttgccaggtt tgacgggaaa tataaaaaaa
    61081 tgtgaggcgg ctcgaaactt aatggctttt tgtgaatgaa ctcacaggtg ccaaatgaga
    61141 attaaaatca ctcctgaaaa ttattattgc cagcccattt atcacttttt ctcttttctc
    61201 aaaatcagtg attccttatc attatgataa agagtgctgg agggattaaa tatttgaacg
    61261 caatcgttta actacgtttt ctaaatttca gtataccttt tcttcgctgt aataaagtcg
    61321 tccggagtat caatatctaa aattatttct gcattttcta tttcgacgga ataatgttct
    61381 cccataagga gtgcctgacg catattggtg acattggggc gctggattgc ctgcatcagg
    61441 catggttttg acactaaaat cggatggccg gggatgccat tatggagtgg cagtattgcg
    61501 ccatcatttc gtaacgacca gatttttcta aaaatatcga tggtgagggt tggcatatct
    61561 ccgtgggtga gaaaacaatg ttctgtttgc accgcgggta ctgcggcctt tactgatgtc
    61621 agtaaaccct gcgcataatc tgggttgtgg ataatagtga tattgctctg gttcgcataa
    61681 cgttcgtgca gttcattacc acgatagccg gtgactaaaa taattcggct acaaaactgc
    61741 aacgcatttt tgatacttgt atcaagaatt gttccctgtt gccagggtaa catcattttc
    61801 cattgcccca ttcttgatga taatcctgcg gcggtaatta tacagtcgat ggctgacata
    61861 gtgattccat tatttacagg agctaataac gcctgataat tgcgttactt cctgatggat
    61921 tacgttgagg gtaatttatc ccagagaggt ccataaagac gcgtgaaaag tataattgac
    61981 ccatcggcat tattcattga tttaggcgcg cagaaacgtc ccactgtgat ttctattgtt
    62041 ggtgctgggg ggaaaaccag cttgcttttt tggctggcag aactgttcca ggcgagtggc
    62101 aggcgtgtat taatcactac gacgacacat atgtttatgc caacatctca ctggcccgtg
    62161 gttttctgtc gtgatcccgc catgcttcct catgcgtctt ttatatcccc catttcattt
    62221 tgttttcact gctggaaagc gaaccaggga aaagtgcagg gatttacgcc agaagcgatt
    62281 gatgcactgg tacaacgacc agagtgtgac gtaattctca ttgaggcaga tggctcgcgt
    62341 ggaatgccgt taaaagcgcc tgatgagcac gaaccttgca tacctaaaag cagttgctgc
    62401 gtgattgctg tgatgggagg acatattttg ggtgcgaaag tgagcacaga aaatgtccat
    62461 cgctggtcgc agtttgctga tattactggg ttaacacctg atgcaccctt gcaactgagc
    62521 gatctcgttg cgctggttcg ccaccctcag ggcgcgttta aaaacgtacc gcaaggttgt
    62581 cggcgagtct ggttcattaa ccgtttttct caatgtgaga atgcgattgc gcaaagcgag
    62641 ctccttcaac cgctgcaaca acacaacgta gaggcaatct ggctgggcga tatacaagaa
    62701 catcctgcaa tcgcgcgcag atttgtgaat tagcggcccg ggtattccgg gttactgaaa
    62761 ggatatccat tgaggttggt atgaatattt tcacagaggc tgcaaaactc gaagagcaaa
    62821 attgtccgtt tgcgatggcg caaattgttg atagccgagg ctcaaccccc cgccattctg
    62881 cacaaatgtt agtgcgcgcc gatggttcta tcgtcggtac aattggtggc ggaatggttg
    62941 agcggaaggt gattgaagag tcgcttcagg cattgcagga acgtaagccg cgattattcc
    63001 atggacgtat ggctcgtaac ggtgcggatg ctgtcgggtc agattgtgga ggtgcaatgt
    63061 cagtatttat cagcgtccat ggtatgcgtc cacgtctggt gttgattggt gcggggcatg
    63121 tcaaccgggc gatagcccag agtgcggcgc tattaggatt tgatatcgcc gttgccgata
    63181 tttatcgcga aagcctcaat cctgaactat tcccaccatc aaccacgctt ctccatgctg
    63241 agtcgtttgg tgcggcagtg gaagcactgg atattcgccc tgataatttt gtcctgattg
    63301 ccacgaataa tcaggatcgt gaagccctcg acaaactcat tgaacaaccc attgcatggc
    63361 tggggttgct ggcaagtcgc cgcaaggttc agcttttcct acaccaattg cgtgagaaag
    63421 gcgtggctga agaacatatt gcccgtttac atgcgcccgt tggttacaac ataggtgcgg
    63481 aaacgccgca ggagatcgcc atcagcgtgc tggcagaaat attacaggtg aaaaataacg
    63541 cgccgggtgg gctgatgatg aagccttctc atccttccgg acaccagctg gtggtgattc
    63601 gcggtgcggg ggatatcgcc agtggtgtag cgctacgtct gtatcatgcg ggttttaaag
    63661 tgatcatgtt ggaagtggaa aaaccgacag tgattcgttg taccgtggcg tttgcccagg
    63721 ccgtgttcga tggcgaaatg acggtcgaag gcgtcaccgc ccgcctggca accagctctg
    63781 cggaagcgat gaaacttacc gaacgcggat ttatccctgt gatggtagat cccacctgtt
    63841 cattgcttga tgaactgaaa ccgctttgcg tggtggacgc tattctggcg aaacagaatt
    63901 tgggaacgcg ggcagatatg gcaccagtaa caatcgcgct tgggccgggc tttactgcag
    63961 ggaaggattg tcatgcggta attgaaacaa atcgcgggca ctggctcggt caggtgattt
    64021 actcaggttg tgcgcaggag aataccggtg ttcccggcaa tattatgggg cataccaccc
    64081 gacgagtgat ccgcgctcct gctgcaggca ttatgcgatc caacgtgaaa ttaggcgatc
    64141 tggtgaaaga gggcgatgtc attgcctgga ttggtgagca tgaaattaaa gcaccgttga
    64201 cggggatggt gcgtggcttg ttgaacgacg gactggccgt ggtcggtggt tttaaaattg
    64261 gtgatatcga tcctcgtggt gaaacggctg atttcaccag cgtttctgat aaagcccggg
    64321 cgattggcgg cggcgtactt gaggcgttaa tgatgttgat gcatcagggc gttaaagcga
    64381 caaaagaagt gctggaagtg gcttaaatga aaatggccgg atggtattac ccatccggcc
    64441 tttaaattac tgacaaatca ccgttccggt tttgccttca atcccttctt tcgctttgct
    64501 caatacggta atcagtgctt cacgacctgc gcgagagcga gcaaacgagg cggcagcttc
    64561 cactttaggc agcatagaac ctttcgcaaa atgaccttct tcgataaagc gttcagcatc
    64621 acttaatgac aggcgatcga gccactgttc attctctttt ccgaagttaa tggccacttt
    64681 ttctaccgca gtcagaatga tcagcatatc ggcatcgatc atttctgcta aacgggcact
    64741 ggcccagtct ttatcgataa ccgcgctggc accacgcaga tggttacctt cacgaataac
    64801 agggatacca ccaccgccaa cggtgatcac cacctgtccg gcatctacca gagctttaac
    64861 cgtttctttt tcaatgatat caaccggttt tggcgaagca acgacacgac gatagccgcg
    64921 acccgcatct tctttcagag tgtaaccctg ttttgtcagt agctctgctt cttgctcggt
    64981 aaagaacgaa ccaatcggct tggtcgggtt gaggaatgcc ggatcgttag catcgacttc
    65041 gacctgggta accagcgttg ctacaggttt attaatgcca cgagaaagca gttcttctct
    65101 taaggcgttt tgtagatcgt aaccaatata accctggctt aaggcaacac agacagacat
    65161 cggcagcatt ggcgagtgcg cttcagtttt tgcggcagct tcaaaggcct ggttaatcat
    65221 gcccacctgt ggcccgttgc catgagtgac gatgacctca tgtccctggg caattaaatc
    65281 aacaattgcc tgagaagtaa tttttaccgc tttcatttgt ccggccaggt catcgcccag
    65341 cgcattcccg cccagggcga gaacaatttt cttactcatt tttcctcact catcattctt
    65401 gattgtgtat agatccctgg cagtggttag agcacgggag ggacaaacgg tttgcgtcgc
    65461 aggaaacgac ctcgcccggc tttgcctgta aaggtgccgt cgcagaaaat cgtttcacca
    65521 cgggataagg ttctgacaat cgcgccctga caggtaaaac cctcccatgg cgagtagtca
    65581 gcgttgtcgt ggagatggcg atgctgaatt tgttggctct gacgtgggtc tataatcacc
    65641 acgtcgccat cggaaccggg cgctaataat cctttttgtg gccacaggcc aaacagcctg
    65701 gcgggcattg cactggttaa ctcaacaaaa cgctccggtg agatacgccc cgtcatcacg
    65761 ccactggaga acagcagttg catgcggttc tccacaccgg gtaagccatt tgggcagcgg
    65821 ctgaaatcgc ctttagaaat ttgcaggcgt tgagccatcg agaaggtgca gtgatcggtt
    65881 gccaccacgt caatcgcacc atcgctgatg ccacaccaca gtttgtcctg ctcgcgtacg
    65941 ttacgcagcg gtgggctaag aatgaacttc atgccatctt ctgtatcgta actgcgttcg
    66001 tccaacagga gatattgtgg gcaggtttca acccagactg gctggtgatt cgcacgggca
    66061 agacgcagat aatccagacc taagccgtta gacaggtgca cgatatagag cggggcgtta
    66121 ccggcaattt gtgccaggtt aatcatgcgg gcgatggctt ccgcttcgca ttccagaggt
    66181 cgactcaagg catgataacg cggcgcggtt aaccctgcgg cgataaactc cgcccgcttg
    66241 ctggcgatag ctgcgtcatt ttccgggtgc acggtggtca gcgcgccgga ctcatgcaag
    66301 cggcgtaatg cctgcaacac ttcatcatcg ttgagtttat attgataggt taaatagagt
    66361 ttaaaactgc tcagtccttc ctcaaccatc atcggaattt cgtcgaggat agcgtgatta
    66421 atatgttgaa tgacaccgtg aaagctgtag tcgatgactg ctttgtgggc ggcataaccg
    66481 cgataaactt ccagttgatg gcgtaaccgg cagccatttg ggccaaatcc catatggtca
    66541 ataatggttg ttgtaccgcc acacgcagct gcgcgggtac cggtaaaaaa atcatcacaa
    66601 ctgcgcgcga tgccgacatc aatattgaaa tgcgtatgga catccacgcc gccagggaaa
    66661 acgtaacagc cagaggcatc aatttcttcg caagggagtt gcggcgaaat atcggtaccc
    66721 aactggcgaa caatcccgct ttcaatcagc aaatcctgct tcgcctgtcc atctgcatta
    66781 acaacaatgc cgttttttat caatacgcgc atagcaaact ccaaaaaccc tccggtgaac
    66841 cggaggggaa taagtgaaga gtaattattc ggttgccagc cagcttaatg ggattgcagc
    66901 gtacatagcg gcacaggtta ccaggtgaga tttccaggtt ttttcgtttg gcgcgtgcgc
    66961 ttccggttct ttaccggggc caaaaccgat gaccggaatg ccgtggcgac ccatgatgga
    67021 tacgccatta gtcgagaagg tccacttatc aacgacaggc gctttaccaa acagcccttc
    67081 ataagcattc accagtgctt taacggtgaa gtgatcttct tccactttcc aggtcgggaa
    67141 gtagcattcg gttgggtaaa ccaggccagt ccaggacggg cggtcgtagt tgtacataga
    67201 aacgacagca ttcgcttttt gtactgcagg cagggcacgg atctcgtcca gcgcgccttc
    67261 ccaggtttcg ccccaggtca gacgacggtc gattgaaact gcgcagctgt ctgcgacagc
    67321 gcaacggctt ggggaggtga agaaaatttc agaaacggtg agggtgcctt tgccgaggaa
    67381 ttcgtcataa cccagacgtt gggagagttc ttgtaattcg ccaagaatcg gacccatttt
    67441 gaaaatggcg ttatcaccgc gttctggtgc cgaaccgtgg cagctaacac cctgaacatc
    67501 aatacgaatt tccatacgac cgcgttgacc acggtatacc tggcagtcgg ttggttcggt
    67561 actgaccaca aattccgggc gaatgccgga ttgttcaata atgtactgcc agcacaggcc
    67621 gtcgcagtct tcttcctgca cagtaccggt aaccagcagg gtatattcat cttccagacc
    67681 gagatcttta atgattttac cggcatatac catagacgcc atgccgcctt cctggtcgga
    67741 agtaccacga ccaccgatca gctcgtcggt ttccatgcct tcatacggat cgaagtccca
    67801 gtttttgatg ttgccaatgc cgactgtatc gatatgagcg tccattgcca ccagacgcgg
    67861 gccgtggccg atataaccga gaacgttgcc cattgggtcg atttcaactt tatcgaagcc
    67921 gactttttcc atctcttctt taatacgatg tactacgcgt ttctcgtcgc agctttcact
    67981 gggaatagca accatatcgc gcaggaagcg agtcatgtct gcctggtaat cttttgcttt
    68041 ttcaagaatc agtttgaatg gaatattctt agccattatt tttctccaga ttttttactc
    68101 cccgttttgc agggagcagt tccaataggg tgattaaggt gctacagcgt gtttgccttc
    68161 ccagacaact tcgcggtagt gcttcacgtc ggtgtcgcct tcagtgctga taaccagcac
    68221 cacggcatct ttgttcagcg ccagtttttc catcaggctt tgacgttgcg ggtgataatg
    68281 aaccgctgcg agaacgccca aaccgacagc gccggattca ccggagatga tgcgcgggtc
    68341 gttgccgtac ggattaccca gcacgcgcat acctaatgcg gcaacgctgt cctggcagga
    68401 gatgaattgg gtggcgcagt tacgtaggat ttcccagccc agcgggttag gttcgccgca
    68461 ggccaggccc gccatgatgg tggccatatc accgccaacg ttgacgatgt cgcctttgac
    68521 gccggagcga taaatacagt cagctttgtc aggttcaaca ataatgctgt gcagattttg
    68581 cgggctatag acgtcgacca gataacccag cacaccaccg gccattgcac cgacacctgc
    68641 ttgcagcaga acgtgtgtcg gggttacgcc catttcacgc atttgctcga cggcttcatc
    68701 cgccagtgtt gcgtagcctt gcatgatcca ggttgggatt ttggtgtaac cttcccatgc
    68761 cgtgtcctgt accacttccc agccgtgctg ctgcgcgtgt tgcatggtca ggcgaacggt
    68821 atcgtcatag ttcatatccg tgacgatgca ctcggcaccg aggtttagaa tggcgtcaac
    68881 gcgttcctga gcagaacctt tcggcatgta aatcaccgca ttctgtccga gttgctgagc
    68941 ggcccatgcc acaccgcgcc cgtggttgcc gtcggtggtg gtcgcgaaag tcattttttc
    69001 gccaatggca tttttcaggt gctcaaatga tagcgtttcg atatcaagat gatatttttc
    69061 acacaataat tgagcgatgg cgtatgcgcc gccgagcatt ttgaaggcgt tcagaccgaa
    69121 gcgttttgat tcgtccttaa cgagaatttt ctttacacca aacaggtttg cgagatcgtc
    69181 cagcgcacaa agcggtgttg ggcgataacc agcaattttc tggtggaact ggcgtgccag
    69241 ttttgcctgg ctttgcgaaa aaagcggtga tgtttcgccg ttgaaaaatt tgttatcggc
    69301 gatatcaatc tttaatgaga aaacggacat atcctatcct tttggcctct ggaaatagag
    69361 ggccgaccag ctgatcggcc cgaggggtta tttcacgcgt tcttgcgctt ctttcagcag
    69421 ttgctcgagc agtgcacctg gtttggcgta tttacgggac aggatcatcg cggcgatgat
    69481 ataaggcttc cagctggctt ctttgtaggt agcgatacgg tatttttcga atacgccttc
    69541 agtcacttca ccttctttgc aggatacgcc gctgatatca gctggcaggc agtgcatgta
    69601 cagggcttcg ccatcacggg tcagctccat catctcttcg gtacaatgcc agtctttgtg
    69661 ctgtgcgttc tgtgccagac actgtttttc cagcgctttc agtccttcgt gatcgttcgc
    69721 acgcagcagt tcagtacgct cttccatcac tttgtaaggt gcccaggact tcggataaac
    69781 gatgtctgcg tctttgaagg cttcttccat gctggtgacc tgacggaagc taccaccgga
    69841 ggctttagca ttgtttttag caacttcaac gacatccggg atcaggtcgt agccttccgg
    69901 atgggccagg gtgacatcca taccgaagcg ggtcatcaga ccgatgatgc cttgtggtac
    69961 agagagcggt ttgccatagc ttggggagta ggcccaggtc atggcgattt ttttaccttt
    70021 caggttttcc agtgaaccaa agtgttcacg taaccatgcc agatcagcca ttgattgagt
    70081 cgggtggtca atatcgcatt gcaggttcac taaagccgga cgctgcggca gcacaccctg
    70141 cttgtaaccg tcatcaagtg cagcgccaac ttcacgcata taggcgttgc ctgcgcccag
    70201 atacatatcg tcgcgaatac cgatagcgtc agcgcagaag gagatcatat tggcggtttc
    70261 acgcacggtt tcgccgtgag cgatttgtga tttaccttcg tcaagatctt gttgtgcaag
    70321 gccgagcagg ttaagcgcgg aagcataaga gaagcgggta cgggtggaat tgtcgcggaa
    70381 tacggaaata cctaatccac tattaaagac tttggttgag atgttttcag cacgcagtgc
    70441 ttttaacgcg gcggcaacgt ccagtacttg tttcagttcg tctggcgtct gttcccacgt
    70501 taacaaaaaa tctttttcat gcaggtgaga ggtcagcgaa ttgatatcct taatcagctc
    70561 attaacagtt ttcatcataa agtcccgata gtggaatgac aggcaaagtg gtttatttca
    70621 ctgtgacgtg ccaaagtgat tggtgttttc acagctatac ctcggactaa caataagtgt
    70681 gccagaatta tccacgcggc tgcgaaaggc taatttgacg gataatgtgt ggggttgatc
    70741 acatattgat gccagtttcc ggttgtttgt aaaatacgaa aacgtttggc tttttttatt
    70801 acgttattta tttgctgcta agtatcagaa ataagataaa gaggcaggct atctctcttc
    70861 agtttgataa acttgccgct gtaattctca tat
//
LOCUS       DAFGPF010000009        66828 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFGPF010000009 DAFGPF010000000
VERSION     DAFGPF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 66828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66828
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.009"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            62..1033
                     /locus_tag="LSX49_000745"
     CDS             62..1033
                     /locus_tag="LSX49_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBL7167194.1"
                     /translation="MKKINFAFIILFLFSLPLIIFYQPWVNALPPTPRHASPEQLEKT
                     VRYLTQTVHPRSADNIDNLNRSAEYIKEVFISSGARVTAQDIPITGGPYKNIVANYGP
                     ADGPLIIIGAHYDSVSSYENDQLTYTPGADDNASGVAGLLELARLLQQQAPKTGVQLV
                     AYASEEPPFFRSDEMGSAVHAASLERPVKLMIALEMIGYYDSTPGSQDYPSPAMSWLY
                     PDRGDFIAVVGRMQDINAVRQVKAALLSSRDLSVYSMNAPGFIPGIDFSDHLNYWQYD
                     IPAVMITDTAFYRNKQYHFPGDIADRLNYQKMAQVVDGVTTLLYNSK"
     gene            1136..1639
                     /locus_tag="LSX49_000746"
     CDS             1136..1639
                     /locus_tag="LSX49_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBL7167195.1"
                     /translation="MGMIGYFAEIDSEKINQLLESTKKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLES
                     LDRSELRKQFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
                     ALTVIVG"
     gene            complement(1706..3163)
                     /gene="nuoN"
                     /locus_tag="LSX49_000747"
     CDS             complement(1706..3163)
                     /gene="nuoN"
                     /locus_tag="LSX49_000747"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HBL7167196.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM"
     gene            complement(3170..4699)
                     /gene="nuoM"
                     /locus_tag="LSX49_000748"
     CDS             complement(3170..4699)
                     /gene="nuoM"
                     /locus_tag="LSX49_000748"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HBL7167197.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALVTMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAIQALVFVHYNATGVWTFNYEELLNTPMSNG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(4863..6704)
                     /gene="nuoL"
                     /locus_tag="LSX49_000749"
     CDS             complement(4863..6704)
                     /gene="nuoL"
                     /locus_tag="LSX49_000749"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HBL7167198.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQAYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(6701..7003)
                     /gene="nuoK"
                     /locus_tag="LSX49_000750"
     CDS             complement(6701..7003)
                     /gene="nuoK"
                     /locus_tag="LSX49_000750"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HBL7167199.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(7000..7554)
                     /gene="nuoJ"
                     /locus_tag="LSX49_000751"
     CDS             complement(7000..7554)
                     /gene="nuoJ"
                     /locus_tag="LSX49_000751"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HBL7167200.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(7566..8108)
                     /gene="nuoI"
                     /locus_tag="LSX49_000752"
     CDS             complement(7566..8108)
                     /gene="nuoI"
                     /locus_tag="LSX49_000752"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HBL7167201.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(8123..9100)
                     /gene="nuoH"
                     /locus_tag="LSX49_000753"
     CDS             complement(8123..9100)
                     /gene="nuoH"
                     /locus_tag="LSX49_000753"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HBL7167202.1"
                     /translation="MSWISPELIEILLTVLKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(9097..11823)
                     /gene="nuoG"
                     /locus_tag="LSX49_000754"
     CDS             complement(9097..11823)
                     /gene="nuoG"
                     /locus_tag="LSX49_000754"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HBL7167203.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSAE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(11876..13213)
                     /gene="nuoF"
                     /locus_tag="LSX49_000755"
     CDS             complement(11876..13213)
                     /gene="nuoF"
                     /locus_tag="LSX49_000755"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBL7167204.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDSGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGAWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(13210..13710)
                     /gene="nuoE"
                     /locus_tag="LSX49_000756"
     CDS             complement(13210..13710)
                     /gene="nuoE"
                     /locus_tag="LSX49_000756"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HBL7167205.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(13713..15515)
                     /gene="nuoC"
                     /locus_tag="LSX49_000757"
     CDS             complement(13713..15515)
                     /gene="nuoC"
                     /locus_tag="LSX49_000757"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HBL7167206.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSY
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(15609..16271)
                     /gene="nuoB"
                     /locus_tag="LSX49_000758"
     CDS             complement(15609..16271)
                     /gene="nuoB"
                     /locus_tag="LSX49_000758"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HBL7167207.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(16287..16730)
                     /gene="nuoA"
                     /locus_tag="LSX49_000759"
     CDS             complement(16287..16730)
                     /gene="nuoA"
                     /locus_tag="LSX49_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HBL7167208.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETDSIANRQR"
     gene            complement(17360..18298)
                     /gene="lrhA"
                     /locus_tag="LSX49_000760"
     CDS             complement(17360..18298)
                     /gene="lrhA"
                     /locus_tag="LSX49_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HBL7167209.1"
                     /translation="MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPST
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQTMESYHNPWQYSPMSAPEGDDSLLIERDIE"
     gene            19218..20435
                     /gene="alaA"
                     /locus_tag="LSX49_000761"
     CDS             19218..20435
                     /gene="alaA"
                     /locus_tag="LSX49_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HBL7167210.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSGYHQL"
     gene            20519..21118
                     /gene="yfbR"
                     /locus_tag="LSX49_000762"
     CDS             20519..21118
                     /gene="yfbR"
                     /locus_tag="LSX49_000762"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HBL7167211.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMVPEELQDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL"
     gene            complement(21177..23009)
                     /locus_tag="LSX49_000763"
     CDS             complement(21177..23009)
                     /locus_tag="LSX49_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBL7167212.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPI
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(23096..23746)
                     /gene="hxpA"
                     /locus_tag="LSX49_000764"
     CDS             complement(23096..23746)
                     /gene="hxpA"
                     /locus_tag="LSX49_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpA"
                     /protein_id="HBL7167213.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLSPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEHIEATETEGITALPGAIALLNHLNKAGIPW
                     AIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            complement(23757..24251)
                     /locus_tag="LSX49_000765"
     CDS             complement(23757..24251)
                     /locus_tag="LSX49_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HBL7167214.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(24334..24789)
                     /locus_tag="LSX49_000766"
     CDS             complement(24334..24789)
                     /locus_tag="LSX49_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HBL7167215.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            25127..26329
                     /gene="ackA"
                     /locus_tag="LSX49_000767"
     CDS             25127..26329
                     /gene="ackA"
                     /locus_tag="LSX49_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBL7167216.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            26404..28548
                     /gene="pta"
                     /locus_tag="LSX49_000768"
     CDS             26404..28548
                     /gene="pta"
                     /locus_tag="LSX49_000768"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL7167217.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIIANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSTKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIDSLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRENYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            28738..30258
                     /gene="yfcC"
                     /locus_tag="LSX49_000769"
     CDS             28738..30258
                     /gene="yfcC"
                     /locus_tag="LSX49_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL7167218.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAIFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(30291..30833)
                     /gene="yfcD"
                     /locus_tag="LSX49_000770"
     CDS             complement(30291..30833)
                     /gene="yfcD"
                     /locus_tag="LSX49_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HBL7167219.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(30891..31442)
                     /gene="yfcE"
                     /locus_tag="LSX49_000771"
     CDS             complement(30891..31442)
                     /gene="yfcE"
                     /locus_tag="LSX49_000771"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBL7167220.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            complement(31498..32142)
                     /gene="yfcF"
                     /locus_tag="LSX49_000772"
     CDS             complement(31498..32142)
                     /gene="yfcF"
                     /locus_tag="LSX49_000772"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HBL7167221.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLALGQPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            32278..32925
                     /gene="yfcG"
                     /locus_tag="LSX49_000773"
     CDS             32278..32925
                     /gene="yfcG"
                     /locus_tag="LSX49_000773"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HBL7167222.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAGLDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLNHETRERAVTLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQHGDERSDS"
     gene            32982..33344
                     /gene="folX"
                     /locus_tag="LSX49_000774"
     CDS             32982..33344
                     /gene="folX"
                     /locus_tag="LSX49_000774"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HBL7167223.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYTDSVSMTLSWQR"
     gene            33365..34258
                     /locus_tag="LSX49_000775"
     CDS             33365..34258
                     /locus_tag="LSX49_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HBL7167224.1"
                     /translation="MNIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPR
                     VTLWQGLAEQSNLNGVDAVINLAGEPIADKRWTHERKERLCQSRWNTTQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRFGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPVRNEQFAHALGHALHRPTILRVPATAIRLLMGESSVLVLGGQRALPKKL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(34417..35190)
                     /gene="hisP"
                     /locus_tag="LSX49_000776"
     CDS             complement(34417..35190)
                     /gene="hisP"
                     /locus_tag="LSX49_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HBL7167225.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSDGSIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKGSLK"
     gene            complement(35198..35914)
                     /locus_tag="LSX49_000777"
     CDS             complement(35198..35914)
                     /locus_tag="LSX49_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7167226.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            complement(35911..36597)
                     /gene="hisQ"
                     /locus_tag="LSX49_000778"
     CDS             complement(35911..36597)
                     /gene="hisQ"
                     /locus_tag="LSX49_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HBL7167227.1"
                     /translation="MLYGFSSVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERR
                     YSVGVKRADL"
     gene            complement(36687..37469)
                     /gene="hisJ"
                     /locus_tag="LSX49_000779"
     CDS             complement(36687..37469)
                     /gene="hisJ"
                     /locus_tag="LSX49_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HBL7167228.1"
                     /translation="MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(37690..38472)
                     /gene="argT"
                     /locus_tag="LSX49_000780"
     CDS             complement(37690..38472)
                     /gene="argT"
                     /locus_tag="LSX49_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HBL7167229.1"
                     /translation="MKKSILALSLLVGLSAAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGPSVKDKKYFGDGTG
                     VGLRKDDAELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(38738..39307)
                     /gene="ubiX"
                     /locus_tag="LSX49_000781"
     CDS             complement(38738..39307)
                     /gene="ubiX"
                     /locus_tag="LSX49_000781"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HBL7167230.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTL
                     SLETDFSLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAVTLPEDLFARWQGA"
     gene            complement(39402..40919)
                     /gene="purF"
                     /locus_tag="LSX49_000782"
     CDS             complement(39402..40919)
                     /gene="purF"
                     /locus_tag="LSX49_000782"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBL7167231.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVVMIIGHGMVAFRDPNGIRPLVLGKRDIDDNRTEYMVASESVALDTLG
                     FEFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIEAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            complement(40956..41444)
                     /gene="cvpA"
                     /locus_tag="LSX49_000783"
     CDS             complement(40956..41444)
                     /gene="cvpA"
                     /locus_tag="LSX49_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HBL7167232.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
     gene            complement(41885..42547)
                     /gene="dedD"
                     /locus_tag="LSX49_000784"
     CDS             complement(41885..42547)
                     /gene="dedD"
                     /locus_tag="LSX49_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HBL7167233.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPATIAANNTEFEPEPA
                     PVVPPKPKPVESPKPKVEAPPAPKPEPKPVVEEKAAPTGKAYVVQLGALKNADKVNEI
                     VGKLRGAGYRVYTSPSTPVQGKITRILVGPDASKEKLKGSLGELKQLSGLSGVVMGYT
                     PN"
     gene            complement(42537..43805)
                     /gene="folC"
                     /locus_tag="LSX49_000785"
     CDS             complement(42537..43805)
                     /gene="folC"
                     /locus_tag="LSX49_000785"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBL7167234.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVGQEKGA
                     LLQRRGVEWNYSVTDHDWTFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            complement(43875..44789)
                     /gene="accD"
                     /locus_tag="LSX49_000786"
     CDS             complement(43875..44789)
                     /gene="accD"
                     /locus_tag="LSX49_000786"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HBL7167235.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            complement(44945..45604)
                     /locus_tag="LSX49_000787"
     CDS             complement(44945..45604)
                     /locus_tag="LSX49_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBL7167236.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFS
                     NPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLLFTYAGYFFGTLPFIQSNLKLMIVGIIFVSILPGVFEFIRHKRAAARAA
                     K"
     gene            complement(45687..46499)
                     /gene="truA"
                     /locus_tag="LSX49_000788"
     CDS             complement(45687..46499)
                     /gene="truA"
                     /locus_tag="LSX49_000788"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL7167237.1"
                     /translation="MSDQQQPPVYKIALGIEYDGSRYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            complement(46499..47512)
                     /locus_tag="LSX49_000789"
     CDS             complement(46499..47512)
                     /locus_tag="LSX49_000789"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL7167238.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFAQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(47578..48714)
                     /gene="pdxB"
                     /locus_tag="LSX49_000790"
     CDS             complement(47578..48714)
                     /gene="pdxB"
                     /locus_tag="LSX49_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HBL7167239.1"
                     /translation="MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVR
                     SVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSS
                     LLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGITTLLCDPPRADRGDEGDFRS
                     LDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALL
                     TCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSK
                     LIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            48813..49808
                     /gene="flk"
                     /locus_tag="LSX49_000791"
     CDS             48813..49808
                     /gene="flk"
                     /locus_tag="LSX49_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HBL7167240.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGAGNQPLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMALKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDIL
                     NQLYQRRVKGIEPRDMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            complement(49805..50983)
                     /locus_tag="LSX49_000792"
     CDS             complement(49805..50983)
                     /locus_tag="LSX49_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose transporter"
                     /protein_id="HBL7167241.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVSAPFKFALLVVGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(51248..52468)
                     /gene="fabB"
                     /locus_tag="LSX49_000793"
     CDS             complement(51248..52468)
                     /gene="fabB"
                     /locus_tag="LSX49_000793"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HBL7167242.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            52627..54633
                     /gene="mnmC"
                     /locus_tag="LSX49_000794"
     CDS             52627..54633
                     /gene="mnmC"
                     /locus_tag="LSX49_000794"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HBL7167243.1"
                     /translation="MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNHLEARFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAYPQAQLQRLHFISFEK
                     FPLARADLALAHQHWPELAPWAEQLQAQWPLPLPGCHRLLLDEGRITLDLWFGDINEL
                     TSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQEAGFTMQKRKGFGRKREMLCGVMELTLPLPCSTPWFNRTGSSKREAAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFAR
                     RFYDLLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPTELAVAVEANAVEQITGVA
                     TNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIHYQYQLQDLSRKDDGWLLNFAGDQ
                     QATHSLVVLANGHQISRFSQTSSLPVYSVAGQVSHIPTTPELAKLKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEETAYSDEDQQQNRQRLIDCFPQVQWAKEVDVSGKEARCGV
                     RCATRDHLPMVGNVPDYDATLVEYASLAEKKDEAVSAPVYDDLFMFAALGSRGLCSAP
                     LCAEILAAQMSEEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG"
     gene            complement(54754..55032)
                     /locus_tag="LSX49_000795"
     CDS             complement(54754..55032)
                     /locus_tag="LSX49_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HBL7167244.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWEHLFQQASQQ"
     gene            complement(55066..55614)
                     /gene="epmC"
                     /locus_tag="LSX49_000796"
     CDS             complement(55066..55614)
                     /gene="epmC"
                     /locus_tag="LSX49_000796"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HBL7167245.1"
                     /translation="MNSTHHYEQLIEIFNSCFADEFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     ALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLANGIPERPARFIKA
                     LQNYYHTPELTAEQFPWPEALN"
     gene            complement(55614..56423)
                     /locus_tag="LSX49_000797"
     CDS             complement(55614..56423)
                     /locus_tag="LSX49_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBL7167246.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALVAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN"
     gene            complement(56423..57247)
                     /gene="mepA"
                     /locus_tag="LSX49_000798"
     CDS             complement(56423..57247)
                     /gene="mepA"
                     /locus_tag="LSX49_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HBL7167247.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IIGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSRQVSNLGMGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPTLWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI"
     gene            complement(57251..58336)
                     /gene="aroC"
                     /locus_tag="LSX49_000799"
     CDS             complement(57251..58336)
                     /gene="aroC"
                     /locus_tag="LSX49_000799"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBL7167248.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTEIPRW"
     gene            complement(58371..59303)
                     /gene="prmB"
                     /locus_tag="LSX49_000800"
     CDS             complement(58371..59303)
                     /gene="prmB"
                     /locus_tag="LSX49_000800"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL7167249.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNRAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPEAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLIAAREHFAIYKD"
     gene            59469..60020
                     /gene="smrB"
                     /locus_tag="LSX49_000801"
     CDS             59469..60020
                     /gene="smrB"
                     /locus_tag="LSX49_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HBL7167250.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWLPPELP"
     gene            complement(60080..60904)
                     /locus_tag="LSX49_000802"
     CDS             complement(60080..60904)
                     /locus_tag="LSX49_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001527383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2544 domain-containing protein"
                     /protein_id="HBL7167251.1"
                     /translation="MKKMSGLFFLLLTGLLSATAWADVTFRDVKTYTGFWGNGATTKV
                     VFRIDVLTPEGVYYGEYAQDGYTLWLGNIPNTVWTGPGSAPTMNITHQSNTVDNSNCP
                     GITDGWSCVDLGVDIIVHGETHGCPWLVSTNTVSTAARGYTYIGPSAKQTRCPTEPVG
                     PYDISWNENYVLHNKMLTLQSTGGVITQTLSTYLMRDGRVCDGSRMDDRGAYCRFMSY
                     MITFSTSGCDDSKVTVTPVAHPITDKQLHDMQIRIDTSSQQPIDATCRFQYILNEL"
     gene            complement(60906..61433)
                     /locus_tag="LSX49_000803"
     CDS             complement(60906..61433)
                     /locus_tag="LSX49_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7167252.1"
                     /translation="MSLKRIFHCAAALAAVLLTPNVQAADNLHFYGNLLSKSCTLVVQ
                     GEVLAEVHFPTVSRRDLMVTGQSARVPVVFQLKDCKGPAQYEVRVTLTGTEDSEQPGF
                     LALDAASTAQGVGIGMEKTDGTAVLINNTSGATFVLSSGNNDLHFNAWLQAKSGRDVT
                     MGDFTASLTATFEYI"
     gene            complement(61430..61909)
                     /locus_tag="LSX49_000804"
     CDS             complement(61430..61909)
                     /locus_tag="LSX49_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7167253.1"
                     /translation="MKRFALCLFGCYCGIAQAADSDITFHGTLVSPPACAISDGKTVE
                     VEFRDVIIDNINGNNFRQNVPYTITCDPDVRDDAWEMTLSWTGSQTSYDNAAIETNVT
                     GLGIELQQNGQPFTLGTPLKINLSTPPTLQAVPVKASDASLSEGTFSAWATLQVDYQ"
     gene            complement(61906..62397)
                     /locus_tag="LSX49_000805"
     CDS             complement(61906..62397)
                     /locus_tag="LSX49_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7167254.1"
                     /translation="MKGVLLPVAGMVLLACGSAWADSKTVNLTLRILVDAPPPCTVKG
                     SAVEFGNVIIKNIDGSNYRQPVGYTLNCSNSVSDDLQMQLQGTTTTINGETVLSTGIN
                     GFGIRIQDASSHAPVALAGNNWLPFNVNSRPGFEAVPVKQSGTQLTASEFSATMTMVV
                     EYQ"
     gene            complement(62414..63166)
                     /locus_tag="LSX49_000806"
     CDS             complement(62414..63166)
                     /locus_tag="LSX49_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBL7167255.1"
                     /translation="MFYKLSCSMVVSTTLAVLLTTTNLAAHASVTPDRTRLVFNESDK
                     SISVTLRNNNEKLPYLAQSWLEDEKGNKITSPLAVLPPVQRIDAMMNGQVKIQALPDI
                     HTLPSDRESLFYYNVREIPPKSGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKV
                     TLTRSGQDYIVNNPTPYHVIISDASTQKKGLTAAGFKPLVMPPKTSQPLKAKMNSAPV
                     LTYINDYGARLPLVFRCEGDTCKVDEAQSLKG"
     gene            complement(63186..65834)
                     /locus_tag="LSX49_000807"
     CDS             complement(63186..65834)
                     /locus_tag="LSX49_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBL7167256.1"
                     /translation="MPNHSNFRLRGIACYIALAISGGSVNAWADDSIQFDPRFLELKG
                     DTKIDLGKFSKKGYVDAGKYNLRVFINKQSLSDEYDINWYVSENDPTKTYACLTPELV
                     AALGLKEGIAKSLQWTHNDECLKPGQLDGMEVENDLSQSALLLTVPQAYLEYTSSDWD
                     PPSRWDDGISGLIADYSLNAQTRHQEQGGEDSHDISGNGTVGANLGAWRFRADWQSDY
                     QHTRSNDDEDDSSNSTTSKNWDWSRYYAWRALPSLKAKLSLGEDYLNSDIFDGFNYIG
                     SSVSTDDQMLPPNLRGYAPDVSGVAHSSAKVTISQMGRVLYETQVPAGPFRIQDIGDS
                     VSGTLHVRVEEQNGQVQEYDVTTASMPFLTRQGQVRYKVMMGRPEDWNHKTEGGFFSG
                     GEASWGVADGWSLYGGALADEHYQSAAMGVGRDLAQFGALAFDVTHSHVNLDHDSAYG
                     KGKLDGNSFRVSYAKDFDELNSRVTFAGYRFSEKNFMTMSEYLDASQSDMARTGNDKE
                     MYTITYNQNFAAAGVSVYLNYSHRTYWDRPEQTNYNLMFSHYFNMGSIRNMSISVTGY
                     RYEYDDNTDKGMYLSMSIPWSDSSTVTYNGSYGSGSDSSQVGYFNRIDDATHYQINVG
                     TSEQHGSVDGYLSHDGTLAKVDLSANYHEGEYRSAGIALQGGATLTAHGGALHRTQNM
                     GGTRLLIDADGIANVPVESNGAPVYTNMFGKAVVADINNYYRNQAYIDLNNLPEDAEA
                     TQSVVQATLTEGAIGYRKFKVISGQKAMAVLRLRDGSYPPFGAEVKNDEQQQVGIVDD
                     EGNVYLAGINAGEHMMVFWEGSAQCEIVLPKPLPADLFRGLLLPCEQKGTTAPDSLAP
                     EIKPVIQDQTRQVTPSEAPTSISATQ"
     gene            complement(65915..66481)
                     /locus_tag="LSX49_000808"
     CDS             complement(65915..66481)
                     /locus_tag="LSX49_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7167257.1"
                     /translation="MSKFAKTAIAAAMVMGAVVSSSAFAAGNNGTARFYGTIEDSPCS
                     IVPDDHKLEVDMGDIGAAKLTGGGTTTPKDFQIHLQDCVFTTESNMETTFTGTNYAGP
                     ANADNYALFNVDSGVAMNHVSLVIGDTHGKGYKVGEKIVQPIVMDASTSKGKDKQTLN
                     FKAWLVGETDAPDLGQFETLTTFQITYL"
BASE COUNT        16441 a        18223 c        16792 g        15372 t
ORIGIN      
        1 tacaatatcg aaacccataa caaataatga ttcaacaacg caacccatta ataatttgca
       61 tatgaaaaaa ataaattttg cttttattat attatttcta ttttcactcc ctctgattat
      121 tttttaccaa ccctgggtga atgcattacc accaacgccc cgacacgcta gtcctgagca
      181 attagaaaaa acagttcgtt atcttacaca aactgtgcat ccacgtagcg ccgacaatat
      241 tgataatctg aatagatccg cagagtatat aaaagaggtc tttatcagta gcggtgccag
      301 agttaccgcg caggatatcc ccattacggg tggcccctac aaaaacattg ttgctaatta
      361 tggtcctgcc gatggaccgc tgattattat tggtgcgcac tatgactctg tcagtagtta
      421 cgaaaacgat caattgacct atacgccggg cgcggatgat aacgccagcg gtgtggcagg
      481 attactcgaa ctggcacgtt tgttacagca gcaagcaccg aaaacaggcg tgcagctggt
      541 cgcctatgcg tcggaagaac cgcccttctt tcgtagcgat gaaatgggga gcgcggtaca
      601 tgcagcttcg cttgagcgtc cagtgaaatt aatgatagcg ctggagatga ttggttatta
      661 cgactctacg cctggtagcc aggattaccc atccccggcc atgtcctggc tttatcccga
      721 tcggggagac tttattgccg tggtcggcag aatgcaggat atcaacgccg ttcgtcaggt
      781 aaaagcggca ttgttgtcat cccgggattt atctgtttat tctatgaatg ccccaggttt
      841 tattcccggt attgatttct ctgatcacct taattattgg caatacgata ttcccgccgt
      901 aatgattact gacaccgctt tttatcgtaa taaacaatac cactttcccg gtgatatcgc
      961 agacagatta aattatcaga aaatggctca ggtagtggat ggagttacaa ccttgttata
     1021 caacagtaaa taataaaaat ttctcgaggc ggatccagaa aaagcaacat gcgcatttta
     1081 ttttctttcg tctgttttaa gatgcgaaac atgaaattca acggaggaaa aataaatggg
     1141 aatgattggc tattttgcag aaattgactc agaaaagatt aaccaactgc ttgagtctac
     1201 taaaaaacct ttgatggata atatacatga cacgctttca ggattacgcc gactggatat
     1261 tgataaacgc tgggattttt tacactttgg cctgacgggt acatctgcat ttgaccccgc
     1321 gaagaatgac ccgctaagtc gcgcagtgct tggtgaacac agcctagaag atggcataga
     1381 tggcttcctg ggattgacct ggaatcagga gttagccgcg acaatcgacc gactggaatc
     1441 actggatcga agtgagctgc gtaaacagtt ttccattaag cgactcaatg aaatggagat
     1501 ttatccggga gtaacctttt cagaagagtt agaggggcaa ctctttgctt cgatcatgct
     1561 tgatatggaa aagctgatta gcgcgtatcg acgtatgctg cgacaaggga atcatgcgct
     1621 gacggttatt gttgggtgat ggtgtcaggg cacccaaaaa aaccgccgaa catgtcggcg
     1681 gctttctgac ttacaaactg actgcttaca tcagcggcat tgctaaccgc acaatgctaa
     1741 tcagcggttg tggccataca cccagcacca gtaccaacag tgcagagatc agcaccacga
     1801 taccgcctgc gctgtactgc cagtttgatg gtgcatcgcg acccggttgt tccggagcgt
     1861 gaaggtataa gctcaccgcc acacgcaggt agtagtagag gccgattgcc gaaccgacaa
     1921 ctacggcacc caccagccac cacaagtgtg cctggacacc gaccgccagc acgtagaact
     1981 taccgataaa gcccagcgtc attgggatac cagccagtga aagcatcatc accgtcatca
     2041 ctgccgcgag gatcggacga tgccagaaca gaccgcggta agagaacagg gaatcagcat
     2101 ccgggccacg atacgggctg gacatcaggc tgaccacgcc gaacgcgccg aggctgctga
     2161 acagataacc tgccaggtaa acccctaccg cttccatcga catctcgccg gtttgcagcg
     2221 caatcagcgc caccagcaga tagccgaggt gagagataga tgagtaaccg agcagacgtt
     2281 tgatattggt ctggctcagc gccatcaggt taccgaagat gatggaggca aaggcgataa
     2341 tcgccagcac tacgcgaatc gcttcactgt cacccaccgg tgcgtaaagg aacaaacgca
     2401 tcaccacgcc gaagatagcg attttgctcg ccgtcgccag gaaagtggaa accggcgcag
     2461 gcgcgccctg gtatacgtct ggcgtccaca ggtggaacgg caccagagag agtttgaagc
     2521 cgaggccaac aatcatcagg ccgaaacctg ccagcaacag cggctcgttg agcataccgt
     2581 cgccgaggtt tttacccagt gcgacaaacg acaggtcgcc agactgcgca tacaccagcg
     2641 ccataccgaa cagcaggaaa gaagacgctg cggcagaaag gatggtgtat ttgatactgg
     2701 cttccagcga acgtttctgg cggaaagcgt aaccgaccag gccaaacagc ggcaaagaga
     2761 tcagttcgat accgaggaac agagacgcca gatggttggc attcgccagc aggatcccgc
     2821 ccagcgcggc aattaacacc aacaggtaga actcatcctt gttgtcgtta tagccttcaa
     2881 gccacgggta ggcgaaagta caggtggcga ggctcgccaa caataccagc ccggtgtaaa
     2941 gcatggcgaa accatcaacg cgcatcagtg gcgtaacgtc catagcgccc gcctggccga
     3001 caaaccagag cgaaaccagc gccgcgttaa gcccaataac cgagagcgta gcgttgagaa
     3061 aatgattgcg tcgccacgca atggagagca tcacaaccac caccgtcaag ccgacgatca
     3121 gcaacggtag cagtgcgatc aggttttgtg gagttattgt catggcgatt tacggccttg
     3181 tagtagtaac ggaattaaca aaccactgct ggatattgcc aatcgcggag tgcgaggtat
     3241 ccagaatcgg ctgcggatag aagcccagca gtaccagcag caccaccagc aacaggatca
     3301 taaacagctc acgcagcgac atccctggca gttcctggct ggcaatctgg cttttcgctt
     3361 taccgaaata agcgcgatgc agcatcgcca gcgaataaac agatgcaaag accagcccaa
     3421 aggtagagat aacggtaatt accgggacaa cctggaagct accgaacaga atcataaatt
     3481 cgccgacgaa gttaccggtg ccaggcatcc caagcgttgc caccgcaaag aacagcgaca
     3541 gtgctggcag ccacttcatc ttgctccaca gaccgcccat catgcgcatg tcgcgggtat
     3601 ggatacgttc atagagctga ccgcagagaa taaacagacc cgccgctgac aagccgtgtg
     3661 caatcatctg gattaccgcg ccctggtagg ccaactggct accggtgtag atagcaatca
     3721 gcacgaagcc catgtgggaa accgaggtgt aggcgatcag acgtttgata tcggtctggg
     3781 cgaaggccat ccacgcacca tagaagatgc cgataacacc cagccacata gcgattggcg
     3841 cgaactctgc cgacgcgttc gggaacagcg gtagggagaa acgcagcaga ccgtaagcgg
     3901 cggttttcag caagatcccc gcgaggtcaa cggaaccggc ggtcggagcc tgggagtgcg
     3961 catccggcag ccagccatgc agcggaacca ccggcatttt cactgcgaag gcgatgaaga
     4021 agcccagcat caacaggtat tccacgccgt tagacatcgg cgtattcagc agctcttcat
     4081 agttgaaggt ccagacgccg gtcgcattgt agtgaacgaa aaccagcgcc tggatggcga
     4141 tcaacatcac cagaccactc gcctgggtgt aaatgaagaa cttggttgcc gccgtgatac
     4201 gcgttttacc gtcagaggct ttatgccccc acagtgcgat caggaagtac atcggcacca
     4261 gcatcatttc ccagaagaag aagaacagga acatgtcgat ggcaaggaac acgccgataa
     4321 cgccgcccag gatccacatc aggttgaggt ggaagaagcc ctggtatttt tcgatctctt
     4381 tccacgaaca gagtaccgcc agcacaccga gcagaccggt cagcacgacc atcagcaacg
     4441 acagaccgtc aatggcgaga tggatagaga taccaaaacg cgggatccac ggcatgtcga
     4501 attcagactg ccactgcgga attccggcgg attgcgtcag tgaataaccg ccctgcaacc
     4561 acagttgcag cgacagcgcc agcgtcaatc ccatggttac cagcgcgatc cagcgcggca
     4621 ccttgacgcc aaagcgttcg gtctgccagc acaggaagcc gccgataaag ggaattaata
     4681 ttagccaggg tagtaacatg gcgatcttta ttccttgtaa aagtcccgtc aggaccggat
     4741 tttcaacgaa ttctcacgac agaaaattct cttcggactg ggggtagtgt cggatgcgcc
     4801 gcgaagacgg cttatccgac ctacgttctt atatgcccag gggcaatccc acaatcctta
     4861 actcaacgca gtaccatcaa cagagccagc accacgaccg caccgatgct catggatgcc
     4921 acataccagc gcagataacc gttctcgctt aacagcagac ctttacctgc aaagcgggaa
     4981 aggacagccg ggatgttcat cattgagttc agcggatcgc gtttcagcaa ccaggcaata
     5041 cccaggaacg gcttgacgaa cactttgtcg tacagccagt caaagcccca ggcgttgtac
     5101 caccaggtac ccagcagacg gcccggcgca ctgttggcga tggaggtcac cagagtacgt
     5161 ttacccagcc acagccaggc agccagcaga atgccgacca ccgcgaccac gccagaggta
     5221 atttccaggg tcaacatgct gccgtgcgcc agctccgtcg tttgcggaag cacgccctgc
     5281 agcggcggta caatcagtgc accaacgaag gtggaaagga tcagcagcac aatcagcggc
     5341 aggctgtgag ttaccccttt cacggcgtga gcgtgaattt gttcttttcc gtggaagacg
     5401 atgaaaatca tacggaaggt gtagagcgag gtcataaacg caccgaccag acctgccacc
     5461 atcagattga tatgtccatt cgccatcgca cccgcgagga tctcatcctt actgaagaag
     5521 cccgcagtga ccagcggcag tgccgatagt gctgcgccgc ccaccaggaa gcagagataa
     5581 accagcggaa tagatttacg cagaccaccc atcttaaaga tgttctgttc gtgatggcag
     5641 gccagaatga cggaaccgga tgccaggaac agcagcgctt taaagaacgc gtgggtcatc
     5701 aagtggaaaa tcgccgcatc ccatgcctgc acgccaagcg cgaggaacat gtagccaatc
     5761 tggctcatgg tagagtaagc gagaacacgt ttgatgtcgg tctgtaccag cgcggcaaaa
     5821 ccggccagca gcagcgtaac cgccccgaca atacccacca gatgcagaac ttccggcgtc
     5881 atcaggaaca ggccgtgggt acgggcgatc aggtagacac ccgcggttac cattgttgcg
     5941 gcgtggatca gcgcggagac aggcgtcggg cccgccatcg cgtcggcaag ccatgtctgc
     6001 aacggcaact gcgcagattt accgaccgca ccgcccagca gcatcagcgt cgcccacatc
     6061 agcatgttat tgccgtcagc aaagtgcgct ggtgccagtt ccaccatttc gcggaagttc
     6121 agggtgccca gttcgttgta aagaatgaac agcgcaaaag cgaggaagac gtcacccaca
     6181 cgggtcacga cgaacgcttt cattgccgct gcgccattct tcggatcggt gtaatagaaa
     6241 ccgatcagca gataggagca caggcccacg ccttcccagc cgaggtacat caacagtagg
     6301 ttatcggcga gaaccagaac taccatgctg gcgatgaaca ggttggtgta agcgaagaag
     6361 cgagagtagc cctcttctcc gcgcatatac caggaggcat acatgtgaat aaggaaaccc
     6421 acaccagtga ccactgagag catggtcagc gacaggccgt ccagcaccag attgaaaccg
     6481 atgttaaagt cgcctaccga catccacgtc cacagcggct ggctatatgc ctgctcaccg
     6541 ttagcgaaga agtcaacgcc gataaaggcg gttaccagcg ccgccaggcc cacagagcca
     6601 acgccgacga tcgccgagac gttttcagac cagcgcccac gggagaacgc cagcaggacg
     6661 aagccaatca atggcaaaat aatggttaag gcaagcatgt tcatccgcgc atctcactta
     6721 ctgaatcgat gttcaggttc tggcgacgac ggtgaagttg cagcagcagc gcaaggccga
     6781 tactcgcttc cgccgccgcg aggctgatgg cgagaatgta catcacctga ccgtcggtct
     6841 ggccccagta gcttccggcg accacaaagg ccagcgcgga ggcgttaatc atgatttcca
     6901 gaccaatcag cataaacagc agattgcgac ggataaccag accggttaag ccaagaacga
     6961 ataagattgc cgcgaggatc agtccatgtt gtaaggggat catgcgtgct cctccgtttt
     7021 tcttttcgcg ctgtcgtctt tacgattgct cagcacttca cccgcacgct cttcacgacc
     7081 gacgtggaag gccacaacca gacccgcgag cagcagcata gaagccagtt ccaccgccag
     7141 tacgtaaggc ccgaacagcg taatacccac tgctttagca ctgattggcg taccgtcgat
     7201 accttgatcg ttaacaccga gaatggcgta aacaatcacc accagcatga tggctgacaa
     7261 aattgccgga ccaatccaca cctgcggttt caaccactgg cgttcctgtt cgatttctga
     7321 accgcccagg ttgagcatca tcaccacgaa cacgaacagc accataatgg cacccgcata
     7381 gacgataatt tccagcgcac cggcaaagta agcgcccagt gagaagaaca ccccagagat
     7441 cgccagcagc gaaataatca ggtacagcag cgcgtgtacc ggattggtat gggtgatcac
     7501 tcgcaaggtc gcaagtatgg ctatcaggcc acagatataa aaagcgaact ccattgcccc
     7561 tctccttacg gtaacaggct cttgacgtcg ataggcttgg cttcgttctc tgcttcgccc
     7621 ttatctttgc cgtcgattgc catacctgcc atccggtaga agttatattc cgggtatttg
     7681 cccggaccgg agatcagcag atcctctttc tcgtaaacca gatcctggcg cttgtattcc
     7741 cccatttcga aatccggggt taactgaatc gccgtggtcg gacaggcttc ttcgcacaga
     7801 ccacagaaaa tgcagcgtga gaagttgatg cggaaaaatt ccggatacca gcgaccgtct
     7861 ttggtttctg ctttttgcag cgagatacag ccgaccgggc aggctaccgc gcagaggtta
     7921 caggctacgc aacgctcttc gccgtccgga tcgcgggtca gaacgatacg accacgataa
     7981 cggggcggca gatagaccgg ctcttccggg tacattcgcg tttcgcgttt ggcgaacgcg
     8041 tgcaggccga tcatccagat actacgaacc tgggtgccga aacctactaa caattctttt
     8101 aaggtcatgg tcttattgcc ccttattgcg cctgccagag aatgacagcc gccgttacca
     8161 gcaagttgat cagcgtcagc ggcaggcaga ttttccagcc gaaggacatt acctggtcat
     8221 aacgcggacg cggtaacgac gcacgaatca aaatgaacat catcataaag aacgcggttt
     8281 tcagcgcgaa ccagatgaat ggcggtaaca acgggccttg ccagccaccg aagaacagcg
     8341 tcaccatcag tgcagagatg gtcacaatcc cgatgtattc gcccacgaag aacagaccga
     8401 acttcatacc ggaatattca atgtggtaac catccgccag ttcctgctcg gcttccggct
     8461 ggtcaaacgg gtgacggtga cacaccgcca cgcccgcgat ggcaaaggta ataaaaccaa
     8521 agaattgcgg gatgacgttc cacacatgcg cctggctgtt gacgatgtcg gtcatgttga
     8581 atgaaccggc ctgcgccacc acgcccatca aggaaagccc gaggaacact tcgtagctca
     8641 gggtctgcgc agaagcacgc atcgcaccca gcagcgagta tttgttgtta cttgaccagc
     8701 ccgcaaacag caccgcgtaa accgccagac ctgccatcat caggaagaac aaaatcccga
     8761 tgttcaggtc ggcaaccacc caacccggac tgactggcac aattgcaaag gccagcagca
     8821 gcgaggtaaa ggcaatcatc ggtgccaggg taaagatgac gcgatccgag aatttcggga
     8881 tccagtcttc tttaaagaac attttgatca tgtccgcaac cagctggagc gaaccgcccc
     8941 agccaacacg gttaggtcca taacggttct ggaacagacc cagcaggcga cgttcgccaa
     9001 agctcatgaa tgccccacag gtgactacca ccagcaggat caccaccgct ttaaggacgg
     9061 tcagcaggat ctcaatcagt tccggtgata tccaactcat tgttgtgcct ccttgagatc
     9121 ctcaagatgc gcgccagcca gcaccggagc aatgccggac atacccatcg gtaagcccac
     9181 ctgccctgcc gtcagccctt cggcgatttc aaccggcagc gtgaccgtgt tgccatcgta
     9241 actaaaggag acgcgtgtac ctgcgttcac ccccaacttc gcggcatccg ctgggttgag
     9301 tttgatgtac ggctgcggca tacggctctg gaagaccgga gcacgctgtg acaattcatc
     9361 gctgccaaac aggtggtagt acggcgcgat acgccatttc ccgtcctgcg gctggaagcg
     9421 tgccggtacg ctggtgaagt aatccagacc gttttcgctg gtttcaaaca gacgcacgcc
     9481 cggatcgcca aaacgcagtt tgccgcccac ttcgtcctgg aatttgttcc acgcctgcgg
     9541 ggagttccag cctggtgccc aggcaaacgg cacttgcgaa cggtgcgcgg tcggctggtt
     9601 gttaccttcc atcgagaagg tgaacatagt gtcaatatcc tgcggctgac gcggctcatg
     9661 aacgctgata ttggcgcgca tggcggtacg accgctatag cgatgcggtt cacgggccag
     9721 tttctgccca cgaatacgga atgtcgcatc cggcgcagca tctttgatac ctgccagttc
     9781 cgggattttc gccacaacag cgtcaatcac gtggtcgagc tgcgtccagt ccacttcacg
     9841 gctcagcagg gtgctatgca gcgagtgcag ccagcgccag ctttccagca tgacagtttt
     9901 gctgtcgtaa taagccggat cgtaaacctg gaagaaacgt tgggcgcggc cttcgttgtt
     9961 gatcaccgta ccgtcgcttt cagcaaagct ggcggcggaa agtaccagat gggcgttttc
    10021 cataatcgct gtgcgttgat ggtcaaccac catcaccagc ggcgctttag ccagcgcagc
    10081 attcacgcgg gtagcggaag cgtgacgatg cagatcgttt tccagcacca ccaccgcgtc
    10141 ggcgcgtccg gtttccagtt cggttaacgc ttcttcaagc gatccaccgc ccataatgcc
    10201 cagccccatg ctgttgacgg aacgggcaat catggtgata ccgacgtcag cgccgcgacc
    10261 tttcagggct ttcgccacgt tagccgcagc ctgaatcact tcagcgctac cagcgttcgt
    10321 cccggagata atcaacggtt tcttcgcacc agccagtgcc tgcacgatga cgtcgatttt
    10381 gctttgcagc tcaggctcaa taccgtcaac cgctggtgca gagttatcca gcgcatgagc
    10441 gatggcaaaa cctaaacgcg cctgatcttc aaccggtgcg cggtaagtcc acgccgcgat
    10501 atcatccaga cgggtgtcat caacgttggt aacaaacagc ggatgcttcg cacgttgacc
    10561 gatgttgagg attgccgcaa tctgccagtc agccactttc tgtgctgccg ccatttcgcg
    10621 cgctttacct ttcaccgcct gacgcactgc cagcgcgacg cgcgcgccgg tctgggtaac
    10681 gtcttcgccc agcaccagta ccgcatcgta agattcgatt tcgcgcagag ccggagtata
    10741 aatgccgcct tcacgcagta ctttcagcgc cagttgcaga cgttcctgct caccgtgagc
    10801 gataccggta tagaagtttt cttcgcccac cagctcacgc agcgcaaagt tgctttccac
    10861 gctggcacgc ggagaaccaa taccgatcac tttcttcgac tgacgcagaa tatctgctgc
    10921 gccctgcatt gcctgttcgg cgttgagggt aatgaaatca tcgccacgac gctgtactgg
    10981 ctgacgcgga cgatctttca ggttgacgta accgtaaccg aaacgaccac ggtcgcagag
    11041 gaagtagtgg tttaccgtac cgttgtaacg gttttcgata cgacgcagtt cgccataacg
    11101 ctcgccgggg ctgatgttac agccgatgga acattgctgg cagatgctcg gcgcaaactg
    11161 catatcccat ttacggttgt aacgctcgga gtgcgttttg tcggtgaata cgccggtcgg
    11221 acaaatttcg accaggttac cggaaaattc gctttccagc gtgccgtctt ccgggcgacc
    11281 gaagtagacg ttgtcgtgcg caccgtaaac gcccaggtcc gtaccgtcag cgtaatcttt
    11341 gtagtaacgc acgcagcggt agcaggcgat gcagcggttc atttcgtgag agatgaacgg
    11401 ccccaaatcc tgattacggt gagtacgttt ggtgaaacgg tagcgacgga agctgtgtcc
    11461 ggtcatcacg gtcatatcct gaaggtggca gttaccgccc tcttcacata ccggacagtc
    11521 gtgcgggtgg ttggtcatca accactcgac cacgctttca cggaactgtt tcgcttcttc
    11581 gtcgtcaatg gaaataaagg tgccatcgga agccggtgtc atacaggaca tcaccaggcg
    11641 accacgcgtg tcttccgcgt tttggtattg cttcaccgca cactggcggc aagcaccgac
    11701 gcttcccagc gccggatgcc agcaaaagta aggaatatca aggcccagag acagacaagc
    11761 ttccagcagg ttgtccgccc cgttgacctc gtattctttg ccgtctacat gaattgtagc
    11821 cattagcatg cttccagttt tctcagtcag agactgagcg ttaatcgaaa ttcggttacc
    11881 agcgctcttt cagcaggttc ggctgaatcc cattaatcaa atgggtattg ctgaacggct
    11941 gtttgattcc cgcctcaaat tcttcgcgga aatatttgat ggcgctctgt aacggctcca
    12001 ctgcaccagg tgcgtgggca cagaaagttt tacccggacc taagaatcga cacagttgct
    12061 caagtgtttc gatatcgccc ggctgacctt caccacgctc cagcgcacgc agaattttca
    12121 cgctccacgg cagaccgtcg cggcatggcg tacaccagcc gcaggactca cgggcgaaaa
    12181 actcttccag gttacgcacc agcgacacca tgttaatctc gtggtcaacc gccatcgcca
    12241 gcgccgtacc cagacggctt cccgctttac cgatactttc gaattccatc ggcaggtcaa
    12301 ggtgcgcttc ggtcaggaag tcggtgcccg cgccgcctgg ctgccaggct ttgaatttca
    12361 ggccgtcacg cataccacca gcgtaatctt caaggatttc acgcgcggtg gtgccgaacg
    12421 gcagttccca cagacccgga tttttcaccc gaccggagaa gcccatcagc ttggtgccag
    12481 catctttact tttcgagatg ttctgatacc actccacgcc gttagcgagg atcgccggaa
    12541 cgttacacag ggtttcgacg ttgttaacgc aggttggttt accccatgca ccggaggttg
    12601 ccgggaaggg cggcttcgag cgtgggttag cgcgacgccc ttccagggag ttgattaacg
    12661 ctgtttcttc accgcagatg tagcgccctg ccccggtatg gacgaacagt tcgaaatcga
    12721 aacctgttcc cataatgttt ttgccaagca gacccgcttc ggtggcttcg gcaatggcac
    12781 ggcgcagatt cactgccgct tcaatatatt cgccacgcaa gaagatgtag ccacgatacg
    12841 ctttcagcgc aaacgcagaa atgagcatac cttccaccag caggtgcggt agttgctcca
    12901 tcagcagacg gtctttatag gtgcccggct ccatttcatc ggcattacac agcaggtaac
    12961 ggatgttcat ggattcgtct ttcggcatca ggctccactt caggccagta gaaaagcccg
    13021 cgccgccgcg ccctttcaga ccagagtctt ttacctgatt aacgatttcg tccggagaca
    13081 gcccggtcag cgccttacgc gcgccttcgt aaccgttttt gctgcgatat tcgtccagcc
    13141 acactggctg tttgtcatcg cgcagacgcc aggtcagcgg atgcgtttcg ggagtacgga
    13201 taatgttttt catttatacc gctccagcag ttcagggatc gcttccgggg tcagatgcgc
    13261 gtgagtgtcc tcatcgatca tcatgtttgg ccctttatca cagttcccca ggcagcaagt
    13321 tggcagcagc gtaaagcgac cgtcaaatgt cgtttgccct ggtttgatgt tcagtttttt
    13381 ctccagcgcc gcctgaatac cctggtaacc gttgatatga cagaccacgc tgtcgcaata
    13441 acggatcaca tggcggccta ctggctgacg gaagatctgg ctataaaacg ttgccacgcc
    13501 ttcgacgtcg ctcgccggaa tacccagcac atcggcgatc gcgtggatcg cgccatccgg
    13561 cacccagcca cgctgcttct gaacgatttt cagcgcttca atggacgccg cacgcgggtc
    13621 ttcgtagtgg tgcatctcgt gctcaatcgc ttcacgctct gccgcactca gctcaaaagc
    13681 ctcggtttgt ggttgttgat tctcgtgcat aattagcggt ccacatctga cataacaaaa
    13741 tcgatactgc ccagataaac aatcaggtca gacaccaggc tgccgcggat cgccgccgga
    13801 atttgctgca aatgcgcata actcggcgta cggatacggg tgcgataact catggtgctg
    13861 ccgtcgctgg tcaggtagta actgttgatc cccttggtcg cctcaaccat ctggaaggat
    13921 tcattggcag gcatcaccgg accccacgac acttgcagga agtgggtgat cagggtttcg
    13981 atatgttgca gcgtgcgctc tttcggcggc ggcgtggtca gcggatgatc cgccttgaac
    14041 gggccttccg gcatgttgtt gaggcactgc tcaagaatgc gcagactctg gcgcagctct
    14101 tccactttca gcattacgcg ggtgtagcag tcagaaacac caccacccac cgggatttca
    14161 aagtcgaagt tttcatagcc agaataagga cgcgccttac gcacgtcgaa gtcgatcccg
    14221 gtagcacgca ggcccgcgcc agtggtgccc cactccagcg cctctttcgc gccataggcg
    14281 gcaacgccct gggaacgacc tttcagaatg gtgttttgca gcgccgcttt ctcgtaagac
    14341 gccagacgtt taggcatcca gtcgaggaac tcacgcagca ggcgatccca gccgcgcggc
    14401 aggtcgtgcg ctacgccgcc aatacggaac cacgccgggt gcatacgaaa accagtgatt
    14461 gcttccacca gatcgtaaat tttctgacga tcggtaaagg cgaagaacac tggcgtcatc
    14521 gcgccgacgt cctgaataaa ggtggagata tacagcaggt gactgttgat gcggaacagt
    14581 tcggagagca ttacgcgaat gacgttaacg cgatccggca cggtgatccc agccagtttc
    14641 tctaccgcca gcacataagg catttcgtta acgcagccgc cgaggtattc gatacggtcg
    14701 gtatacggaa tgtagctgtg ccaggactgg cgttcgccca ttttctcagc gccacggtgg
    14761 tggtaaccga tgtctggtac gcagtcgaca atctcttcgc catcaagctg caaaacgata
    14821 cggaaagcac cgtgcgcaga cgggtggttc ggaccgaggt tgaggaacat gaagtcctcg
    14881 ttttcggtgc cgcgcttcat cccccactct tccggtttga aggtcagggc ttccatctcc
    14941 agatcctgtt tggctttggt cagctcaaac ggcgagaatt cggtagcgcg cgccgggtaa
    15001 tctttacgca gcgggtgacc tttccaggtt tgcggcatca tgatgcggcg caggttcggg
    15061 tgaccgtcga atgtaatgcc aaatagatcc caggtttcac gctcatacca gttagcgttc
    15121 gggaatagtt tggtaaaggt cggtacgtgc aggtcgtttt ctgccagcgc caccttcagc
    15181 atgatgtcgc ggttacgatc gatagaaatc agatggtaga aaacggaaaa atccgcggca
    15241 ggtaaccctt cgcggtgtgt gcgcagacgt tcgtccatgc cgtgtaagtc aaacagcatg
    15301 acgtaaggtt tcggcagttt ctttaagaaa tcgcccactt ccagtaattg ttcacgcttg
    15361 atccacacaa cgggaacccc ggtgcgagtc gcctgaacag taaaggcatc cggcccaaaa
    15421 cggttgcgca gttcgccaat caccggatca tcaagatgat cgcgggtctg ccaggcgggt
    15481 tcttgcgcgg ttaagtcggt catattgttc accattgcaa atggtccgtg gtgactgtcg
    15541 gcgcagtaag cttcgcgaaa tagatttagg aataagcgaa gaaaattccc tttgccgaca
    15601 ggcgcaaatt aaatctcgtc aggtgtacgc aggttggtta cggcaatgcg ttcaccgcgc
    15661 ttgcgttcgc gctctgattg catattggcg cgataaacgc cctgatcgcc aaccacccag
    15721 gagagcggac gacgttcttt accgatagat tcctgcaaca gcatcagtgc ctgcatgtac
    15781 gcttcaggac gcggcggaca gcccgggata tacacatcaa ccgggatgaa tttatcaacg
    15841 ccctgcacaa cggaataaat atcgtacata ccgccggagt tggcacaggc acccattgag
    15901 ataacccatt ttggttccag catctggtca tacaaacgct gaataaccgg tgccattttg
    15961 gtaaagcagg ttcctgcaac caccatcagg tcagcctgac gcggcgaagc acgcaatact
    16021 tcagcgccaa aacgcgccac gtcatgcacc gcggtaaacg aagtcaccat ctcaacgtaa
    16081 cagcaggaaa ggccgaagtt atacggccaa attgagtttt tacgacccca gttaaccatg
    16141 tcattgagct tgcccataaa cacgtttttg ttaacttctt gctccagagg gtcggttacg
    16201 atctcctgct tttgcagggg gtaacggtcg ttctcaccgt tgggatctat gcgggtgagc
    16261 gtataatcca tcttaatgcc tcgcggttag cgttgacgat tagcgatact gtccgtttcc
    16321 gggttcatac gctcgcggcg tgaacgcgcg ggcgtccagt ccagcgcgcc aatacgcacc
    16381 agataaacca gacctgccag taacacaaaa ataaaaattg cagcttccac aaagcctacc
    16441 cagccgcttt cgcggataga ggttgaccat gcgaacagat acagcgcttc aacgtcgaag
    16501 ataacgaaga acatggccac cagataaaac ttggcggaca ggcgtaagcg ggcggagccg
    16561 accgagtcga taccggattc aaacggaacg ttttttgacc tcgcgcgtgc gcgaccgcct
    16621 aaaaaccaac cgcctaccag catcaggcaa cacaggccaa tggcaacgat aagaaagata
    16681 gcgaatgccc agtgatgagc gatgacttca gtggatgttg acatactcat tgcttactca
    16741 tcaaaagtag cgccagattc actgctcttc acggcagatg gacgccacat cgattcatgg
    16801 ggaggaataa aaaaaacctt acaataactg cagaaactat tttatacagc taattgatgt
    16861 ggtcttttac tcctttctat aaccttttgt caactttaac aaaggtttct tcacactgat
    16921 ttacacaatg acaacaacat ttgcatttgg cgccctttct ccccagatca ttgacgactc
    16981 caggaaaatt agatgttgtt gaatcgtgtc cgttgtgaag caatggaaaa aatacgggtc
    17041 tattttgaca ggaatttgtg tcgattcctc cccccaaaag agagtatttt cttgatctgt
    17101 gacacgcttt tgtcattcta taacaaaaac gcagcaacaa attcacgtat tttttaacat
    17161 tattgtagca ggagattttt ttcaggtgat tatttgtgcg tacggggcgt gaatctctgg
    17221 tgattgaaaa atgaacagtt ttatacgttc tgcacgatac gaggaaggct ttttactaaa
    17281 aaaaagccgc tggggtttaa aataaaccca gcggttcgtt tttacactat tgtctcagga
    17341 attatctatc gtccgtcgat tactcgatat ccctttcaat caacaatgag tcatctcctt
    17401 ccggagcaga cattgggctg tattgccacg gattatggta gctctccatc gtctgataga
    17461 tcacctgggc cagctcatta ttactggacg ggtcatagca cagcaaatat tcggtatcag
    17521 gtagcggcgg taagccatct actccactca gcacacgcag gtccggactc atcatctcga
    17581 ccggccttgc cgtcacgcca agaccggctt tcactgccgc acgaacggcc ggaagcgtcg
    17641 aggcgacata agccagtcgc cagggaatat ctgctttatt aagcgtcgcc agcaccatat
    17701 cgcgaaacgg acttggatca tccagcaaca caagagggat cggctcacct ttttgcaata
    17761 cgtattccgc tgcgcagtac cagtgtgttg gcgaggtacg caggttcaat gccttaaagg
    17821 tagaaggacg atgggtggtt accatcaaat ccacttcctg ggattccagc atttctgcca
    17881 tgtaggcatt acgtttaacg cggacatcca gcgctagttt cggataaacc gaactcacgc
    17941 gatttaacag gaaaggtaag atcgtatcgg cagattcatc tgaagcaccg atagttaaca
    18001 cgccctgaag attactgaac attaatgatg agcaggcctc atcattaaaa cgcaggattt
    18061 tcctggcgta accaagaagt tgaatgccat gttcagttaa cagtttgttg cgaccgtgac
    18121 gagcgaacag ttctttccca acgagttgtt ccagacgctg catttgctga cttacggcgg
    18181 actgagtacg acacacagcg gcagctgcgg cagcaaaagt gttcagatcg gcaacagcaa
    18241 caaatgttct cagcagatcg aggtcgaggt taattatcgg acgatttgca cttatcatat
    18301 attatcactt actggcggct catactgagc tggttaatgc tgtgcacaca caaacaagca
    18361 attccatttg taatgtgcct ccctggcagt ttcatccgga acccggacga aagtaaaaat
    18421 gcatatgagt tgcactaaaa aagcgactca cattgttccg ttataatgcc tgaagtagat
    18481 cacagaatat atcttcaggg atcgcatatc tattaagtta ctcactcttt tctatttatg
    18541 acatgcgcgt gtttgtataa atgtaaatgt gagtccttgt tccactctcg tacagcatcg
    18601 ctggtcatac gcgaacacgt acaaacagca atggtgaggc ggcatcaaga gcagggatcc
    18661 gtcatttatg caagcatttt accccaaaaa ccttttattt ataagggtca ttgcgaatta
    18721 tctgatgcaa agttatgtta tgttaggcaa agtaatcttc tattattaat aagcacaaca
    18781 aaaccttttt gaatattaaa taataattaa ttagcttcat ccccattcat taattccgct
    18841 taacaatagt ttcacacctt gcccccattg tgacacctcg gaaatcatca cgctgttaaa
    18901 ctctccgtaa tgcggaaata tcatcatcgc gattcagtag tgaattctta aacgaggcat
    18961 tttcacacaa ttatcttaca gataaaaaaa ccacacttac aattaagaat cagaacaatt
    19021 cactacataa cattacttat taagcatatg cacctcatta ttttgccatt attaagttat
    19081 taacagcaca atcgagcctt cccctctggc aaaatcttat tctgcagacc ttcaaaacac
    19141 cgtcctgggg gagtacattg ttctaagctg acttccacgg cagggagtgg cgataacagc
    19201 aaaaaaggtc aagattcatg tcccccattg aaaaatccag caaattagag aatgtctgtt
    19261 atgacatccg tggtccggtg ctgaaagaag caaaacgcct ggaagaagaa ggtaacaagg
    19321 ttctgaaact gaacatcggc aaccctgccc cgttcggttt tgacgcgcca gatgaaattc
    19381 tcgttgacgt gatacgcaac ctgcctaccg ctcaagggta ttgcgattcc aaaggtcttt
    19441 actccgcgcg taaagccatc atgcagcact accaggctcg tggcatgcgt gatgttaccg
    19501 tggaagatat ttacatcggc aatggtgtat cggagcttat cgttcaggca atgcaagcat
    19561 tgctgaacag cggggacgaa atgttggttc ctgcacctga ttacccacta tggaccgcgg
    19621 cggtttcact ctccagcggt aaagcggtgc attatctttg cgatgaatcc tctgactggt
    19681 tcccggacct cgatgatatt cgcgctaaaa ttacgcctcg tacgcgtggg atcgttatta
    19741 tcaacccaaa taacccaacc ggcgcggtat attccaaaga gcttttaatg gagattgtgg
    19801 agattgcacg tcagcataat ctcattatct ttgccgatga aatttatgac aaaattctct
    19861 acgacgacgc tgagcatcac tccattgcgc cgcttgcacc tgacctgctg accattacct
    19921 ttaacggact gtcgaaaacg taccgcgttg caggcttccg tcaggggtgg atggtgttga
    19981 acgggccgaa aaaacacgct aaaggttaca tcgaaggtct ggaaatgctg gcttcaatgc
    20041 gcctgtgtgc taacgttcct gcgcaacacg ccattcagac cgcactgggt ggttatcaga
    20101 gcatcagtga atttattacc cctggcggtc gtctttatga gcagcgtaac cgcgcgtggg
    20161 aattgatcaa cgatattccg ggcgtttcct gcgtgaaacc tcgtggtgcg ctgtatatgt
    20221 tcccgaaaat cgacgccaaa cgctttaaca ttcacgacga tcagaaaatg gtgctggatt
    20281 tcctgttgca ggaaaaagtc ctgttggtgc aagggacggc attcaactgg ccgtggccgg
    20341 atcacttccg cattgtcacg ctaccgcgtg tcgatgatat cgagctgtct ttgagtaagt
    20401 tcgcgcgttt cctttctggt tatcatcagc tgtaatctta atttcactgc cggagattgc
    20461 atccggcagt gttatcccgc cacaatgacc tgatgatgtc atcatacgta aggtcactat
    20521 gaaacagagc catttttttg cccatctctc ccgcctgaaa ctcattaacc gctggccgct
    20581 aatgcgcaac gtgcggacgg aaaatgtgtc cgaacacagt ttgcaggtag cgatggtcgc
    20641 ccatgcgctg gcagctatca aaaatcgtaa atttggcggt aatgtcaacg ccgaacgtat
    20701 cgctttactg gcgatgtacc acgatgcttc agaagtgctc accggagatc tccctactcc
    20761 ggtgaaatac ttcaattcgc aaatcgctca ggaatacaag gctattgaaa aaatcgctca
    20821 gcaaaaactg gtcgatatgg ttccggaaga gctacaggat atctttgcgc cgttaattga
    20881 cgagcatgca tatagcgatg aagaaaaatc gctggtgaaa caggcagatg cactgtgtgc
    20941 atatctgaaa tgtctggaag aactcgcggc cggaaataat gaattcttgc tggcaaaaac
    21001 gcgactggaa gcgacgcttg aagcgcgtcg cagccaggag atggactact tcatggaagt
    21061 atttgttccc agcttccatc tttcgctcga tgagattagc caggattcac cgctgtaagc
    21121 agctggagtc tgcgtcgcat caggcaataa gcgccggatg cgacatcagg ctcttgtcaa
    21181 aacggaaaca gcatcgggat catcaccaca caaaccgcca tcacgataat ggtgaacggt
    21241 acccccaact taacaaagtc actgaagctg taattccccg gacctaaaac cagtgtgtta
    21301 acaggtgaag atatcggtgt cataaaggcg gcggatgctg ccatcgccac gaccatcgca
    21361 aatggataag gcgacacccc catcgttttg gcagcagcca gcgcaatcgg agccatcaac
    21421 accgccgtcg cagtattaga aataaatagc ccaataaccg ccgacaagac aaacaaacaa
    21481 cccagcatca tatgtggccc ataaccgccg ccaatgtcca tcagcccttt caccgccagc
    21541 gcgacacctc ccgttttctg taatgccaca gcaaacggca tcatcccaac gatcaaaata
    21601 atgctcggcc agtgaatgga tttataggca ctttcggcat cgatacagcg gaatttcccc
    21661 atcagcaggc aggcgatgat agcggcaaca ggattaggaa tttcatcggt cagcattaac
    21721 gccaccatta gcaccagaca gaaaatggca tggggtgcct ggctgtgcgc gggcgatgct
    21781 tcactcacct cttccggtaa gttcagcgcc acgaagtcgc ggccctgttt ggccagcata
    21841 ccgatcagtt tccagttacc aacaaccaga atgatatcgc ccagcagcag aggctcatcc
    21901 gccagcgaac cttccagcgc cacaccattg cgctttagcc ccaccacatt caatccgtag
    21961 cgggtacgaa aaccaatttc gcgcaccgat ttaccaataa gttctgactc aggaattaat
    22021 gaaatctctg ccatgcccac atcaagggcc tggtcagaaa aatactcgcc gcgcagtacc
    22081 atcggctcca gcaattgctc actacaaaat tgccggagat cgacatcagc cgcagacata
    22141 tcaataagca aaacgtcacg cgcgcgaaat tcagaaaccc cattaacgtt cacgataacg
    22201 cgacgaaaac gccgccagcg ttcaacaccg atgacgttag caccataacg ttcacgtaat
    22261 ttgagatcgt ccagtcgttg accaatcatt ggcgatccgg ggcgaatagc cagacgtcgc
    22321 gcacgcccgg tcagtcgata ttcacggata agatcgcgaa aggttcggcg cgtccagcct
    22381 tcgcgttgtg gggtctgggt atcccctttc agcatgaaac gcatcactaa catatacaaa
    22441 atacccagca ccagcacgac caggccaata ggtgttacgc taaagaaact gaagccgtga
    22501 tagccttcac gcagtaattc actgttgact accaggttcg gcggcgtcgc caccagcgtc
    22561 atcatgccgc ttatcagccc ggcaaaactt aacggcatca tcagacgcga cggcgacgtt
    22621 tgcatacgca tggcaacgct taacaccacg gggataaaga tagcgacaac gccggttgaa
    22681 ctcataaacg cgccaagtcc cgcgacggtc agcatcaaca aaaccaacat tttgatttca
    22741 ctgttgcccg ccactttgac cagccatgtc cccattacag tggcaacacc ggtacggacc
    22801 aaaccatcgc caataatgaa caaggcggca atcaggacaa cgttaggatc ggaaaagccg
    22861 gaaaatactt cggggaccgt cagcgttccg cttaatgcaa acgcgacaat aacaaacaaa
    22921 gcgaccgcat ccatacgcac tctgcccgtc gcaaacaaga cgatggcaac ggccagtaat
    22981 gaaagaaccc aaatcaattc accgttcaca acttatcctt gttaattgag ggggataact
    23041 tgattctgcc ataaaaaagc cccgacgaga cggggctaaa tcatgatcag gtgtttcact
    23101 gaataataac atcgccattt ggctgtttgg tcacagtaat ttgctccaga ctgtggagga
    23161 ctaaatcgac ttcattcagg cgcggggtat ctgccggggc attaaccgca ataacatggc
    23221 aacccgccgc cagacctgaa agcacgccag cgggagcatc ttccaccaca acacactcct
    23281 gcggcgcaag ccccagcagc tgcgcgccta acagatacgc atcaggttct ggttttccgc
    23341 gcttcacccg ctcagcggtt acaaacacct ctggcgcggg aagccccgct attttatgac
    23401 gcgctcgcgc taccggcatg gagccagaag tcacaatagc ccacggaata cctgctttat
    23461 tcaaatgatt gagtaaggcg attgcccccg gaagcgcggt aataccttcg gtttccgtgg
    23521 cctcgatgtg ttccagacgc gtaaactcgg cggcaatgtc tgcctcggat ttgcccgcca
    23581 taaaatggcg cagagaggtg atcgcctgtt taccgtgaat gaaagccagc acctcttccg
    23641 gcgataaccc atgacgtctg gcccagttgc tccacgcccg ttctaccgca ggcagggaat
    23701 ccaccagcgt tccatcaaga tcaaacagaa aacctttgca ccgcacgcgg gcctcctcag
    23761 gcgttaataa tttgattaat ttcgttggcg ctcaaatggt actgacgcgg gcaggcatgc
    23821 cacacattaa gcatgcgctg atatttttcc cacattggcg tctgggcgtt aaaaccgtga
    23881 gttccagcgt caaaatgggt atagcgccct tccacattaa ccataaagcg gacataaccg
    23941 aggtaacgtg cttcagtggc ggcgtcaaag ccgaggaagg tgacacgacg ttcatcgatg
    24001 gattgctggt cctgcaaatt agaccaggaa acatgcaacg catgatacat ctccataatg
    24061 tcgatgatag tgcggcaggt ttcttctttc agctcgccaa actcgcgatc cagttcacgc
    24121 atctgtaatc cataaccacg ctcaatgatt gtttgcaggc gacggtaacg ttcagcattt
    24181 gccggatcga gcatagtcat catcttgtac tggttagaca aaataagacg ttgcgcgttg
    24241 gtcatttcca ttattgactc ctgtatcact ctactacggt gaaaaaaaag aaggctgagt
    24301 atgccttctt ttatatgcgt aatcaggggt caattacaaa tcatcaagga aagttttatc
    24361 cagttgtttg aaggcacgct taagcgtgtc agctaatgcc tggtaatcag gcttgccttc
    24421 aacgggtgcc aacacctgtc cagactcctg caatttaccg cgaacttcat aaaaccagtt
    24481 gaggattgca ggaggtaatg gcgttacaga acgcttgccc agccaccaca atccctgcat
    24541 gggtaaactt aaggcgaaca gcgcagtggc aactgccggc ccaagctgac cgcccagggc
    24601 aatctgccag cagagagtaa atacggcgat cggcggcata aaacggatcg cataacgcgt
    24661 catcttgata acgcgatttt cgacaaagac tggggcaagg cgtttttcca gcggccacgt
    24721 ctttgagtaa tgctgtcccc ggcgaaacaa gctaaaaaaa ttaacagaac gattatccgg
    24781 cgttgacatg cttcacctca acttcacata taaagattca aaaatttgtg caaattcaca
    24841 actcagcggg acaacgttca aaacattttg tcttccatac ccactatcag gtatccttta
    24901 gcagcctgaa ggcctaagta gtacatattc attgagtcgt caaattcata tacattatgc
    24961 cattggctga aaattacgca aaatggcata gactcaagat atttcttcca tcatgcaaaa
    25021 aaaatttgca gtgcatgatg ttaatcataa atgtcggtgt catcatgcgc tacgctctat
    25081 ggctccctga cgttttttta gccacgtatc aattataggt acttccatgt cgagtaagtt
    25141 agtactggtt ctgaactgcg gtagttcttc actgaaattt gccatcatcg atgcagtaaa
    25201 tggtgaagag tacctttctg gtttagccga atgtttccac ctgcccgaag cacgtatcaa
    25261 atggaaaatg gacggcaata aacaggaagc ggctttaggt gcaggcgccg ctcacagcga
    25321 agcgctcaac tttatcgtta atactattct ggcacaaaaa ccagaactgt ctgcgcagct
    25381 gactgctatc ggtcaccgta tcgtacacgg cggcgaaaag tataccagct ccgtagtgat
    25441 tgatgagtct gttattcagg gtatcaaaga tgcagcttct tttgcaccgc tgcacaaccc
    25501 ggctcacctg atcggtatcg aagaagctct gaaatctttc ccacagctga aagacaaaaa
    25561 cgttgctgta tttgacaccg cattccacca gactatgccg gaagagtctt atctctacgc
    25621 cctgccgtac aacctgtaca aagagcacgg catccgtcgt tacggcgcgc acggcaccag
    25681 ccacttctat gtaacccagg aagcggcaaa aatgctgaac aaaccggtag aagaactgaa
    25741 catcatcacc tgccacctgg gcaacggtgg ttccgtttct gctatccgca acggtaaatg
    25801 cgttgacacc tctatgggcc tgaccccgct ggaaggtctg gtcatgggta cccgttctgg
    25861 tgatatcgat ccggcgatca tcttccacct gcacgacacc ctgggcatga gcgttgacgc
    25921 aatcaacaaa ctgctgacca aagagtctgg cctgctgggt ctgaccgaag tgaccagcga
    25981 ctgccgctat gttgaagaca actacgcgac gaaagaagac gcgaagcgcg caatggacgt
    26041 ttactgccac cgcctggcca aatacatcgg tgcctacact gcgctgatgg atggtcgtct
    26101 ggacgctgtt gtattcaccg gtggtatcgg tgaaaatgcc gcgatggttc gtgaactgtc
    26161 tctgggcaaa ctgggcgtgc tgggctttga agttgatcat gaacgcaacc tggctgcacg
    26221 tttcggcaaa tctggtttca tcaacaaaga aggtacccgt cctgcggtgg ttatcccaac
    26281 caacgaagaa ctggttatcg cgcaagacgc gagccgcctg actgcctgat ttcacaccgc
    26341 cagctcagct ggcggtgctg ttttgtaacc cgccaaatcg gcggtaacga aagaggataa
    26401 accgtgtccc gtattattat gctgatccct accggaacca gcgtcggtct gaccagcgtc
    26461 agccttggcg tgatccgtgc aatggaacgc aaaggcgttc gtctgagcgt tttcaaacct
    26521 atcgctcagc cgcgtaccgg tggcgatgcg cccgatcaga ctacgactat cgtgcgtgcg
    26581 aactcttcca ccacgacggc cgctgaaccg ctgaaaatga gctacgttga aggtctgctt
    26641 tccagcaatc agaaagatgt gctgatggaa gagatcatcg cgaactacca cgctaacacc
    26701 aaagacgctg aagtcgttct ggtggaaggt ctggtcccga cacgtaagca ccagtttgcc
    26761 cagtctctga actacgaaat cgccaaaacg ctgaacgcag aaatcgtctt cgttatgtct
    26821 cagggcactg atactccgga acagttgaaa gagcgtatcg aactgactcg caacagcttc
    26881 ggcggtgcaa aaaacaccaa tattaccggc gttatcgtta acaaactgaa cgctccggtt
    26941 gatgagcagg gtcgtacccg tccggatctg tccgagattt ttgacgactc caccaaagca
    27001 aaagtgaaca acgttgatcc ggcgaagctg caagaatcca gcccgctgcc ggttctcggc
    27061 gctgtgccgt ggagctttga cctgatcgcg actcgtgcga tcgatatggc tcgccacctg
    27121 aatgcgacca tcatcaacga aggcgacatc aatactcgcc gcgttaaatc cgtcactttc
    27181 tgcgcacgca gcattccgca catgctggag cacttccgtg ccggttctct gctggtgact
    27241 tccgcagacc gccctgacgt gctggttgcc gcttgcctgg ctgccatgaa cggcgtagaa
    27301 atcggtgccc tgctgctgac tggcggctac gaaatggacg cgcgcatttc taaactgtgc
    27361 gaacgtgctt tcgctaccgg cctgccggta tttatggtga acaccaacac ctggcagact
    27421 tctctgagcc tgcagagctt caacctggaa gttccggttg acgatcacga gcgtatcgag
    27481 aaagttcagg aatacgttgc taactacatc aacgctgact ggatcgattc tctgactgcc
    27541 acttctgagc gcagccgtcg tctgtctccg ccagcgttcc gttatcagct gactgaactt
    27601 gcgcgcaaag cgggcaaacg tatcgttctg ccggaaggtg acgaaccgcg taccgttaaa
    27661 gcagccgcta tctgtgctga acgtggtatc gcaacttgcg tactgctggg taatccggca
    27721 gagatcaacc gtgttgcagc ctctcagggt gtagaactgg gtgcaggcat tgaaatcgtt
    27781 gatccagaag tggttcgcga aaactatgtt ggtcgtctgg tcgaactgcg taagaacaaa
    27841 ggcatgaccg aaaccgttgc ccgcgaacag ctggaagaca acgtggttct cggtacgctg
    27901 atgctggaac aagatgaagt tgatggtctg gtttccggtg ctgttcacac caccgcaaac
    27961 accatccgtc cgccgctgca gctgatcaaa actgcaccgg gcagctccct ggtatcttcc
    28021 gtgttcttca tgctgttgcc ggaacaggtt tacgtttacg gtgactgtgc gatcaacccg
    28081 gatccgaccg cagaacagct ggcagaaatc gcgattcagt ccgctgattc cgctgcggcc
    28141 ttcggtatcg aaccgcgcgt tgctatgctc tcctactcca ccggtacttc tggtgctggt
    28201 agcgacgtag aaaaagttcg cgaagcaact cgtctggcgc aggaaaaacg tcctgatctg
    28261 atgatcgacg gtccgctgca gtacgacgct gcggtaatgg ctgacgttgc gaaatccaaa
    28321 gcaccgaact ctccggttgc aggtcgcgct accgtgttca tcttcccgga tctgaacacc
    28381 ggtaacacca cctacaaagc ggtacagcgt tctgctgacc tgatctctat cggaccgatg
    28441 ctgcagggca tgcgcaagcc ggttaacgac ctgtcccgtg gcgcactggt tgatgatatc
    28501 gtctacacca tcgcgctgac tgcaattcag tctgcacagc agcagtaatc tcgtcatcat
    28561 ccgcagcttt gcgctgcgga tatctgaacc ggaaatagtc actatttccg gttttttatt
    28621 ctcttaattt gcattaatcc tttctgatta tcttgcttaa ctgcgctgca tcaatgaatt
    28681 gcgccatctc actttgcata cttaccactt tgttttgtgc aagggaatat ttgcgctatg
    28741 tccgcaatca ctgaatctaa accaacaaga agatgggcaa tgcccgatac gttggtgatt
    28801 atcttttttg ttgccatttt aaccagcctt gccacctggg tagttccggt gggcatgttt
    28861 gacagtcagg aagtgcagta tcaggttgat ggtcaaacaa aaacacgcaa agtcgtagat
    28921 ccacactcat ttcgcattct gactaacgaa gcaggcgaac ctgagtatca ccgcgtacag
    28981 ctgttcacga cgggcgatga acgcccgggt ctgatgaact tcccgtttga agggttaacc
    29041 tcaggatcga aatacgggac agccgttggc atcatcatgt ttatgctggt gattggcggc
    29101 gcgtttggca ttgtgatgcg tacaggaacc attgataacg gtatcctggc gcttattcgc
    29161 catacccgcg gaaatgaaat tctctttatt cctgcgctgt ttattctgtt ttcacttggc
    29221 ggcgcaatat ttggtatggg agaagaggcc gtcgcctttg ccattatcat cgcaccgcta
    29281 atggtccggc tgggctatga cagtattacc accgtccttg tgacctatat tgccacgcaa
    29341 atcggttttg ccagttcgtg gatgaacccg ttttgtgtgg ttgttgctca gggtattgcc
    29401 ggcgttccgg tgctttctgg ctccgggttg cgcatcgtgg tgtgggttat cgccactctg
    29461 attggcctga tctttaccat ggtgtacgcc tcacgagtga aaaagaatcc tcttctgtca
    29521 cgcgtgcatg agtccgaccg cttctttcgt gaaaagcagg ctgatgttga acaacgtccg
    29581 tttacctttg gtgactggct ggtattgatt gtcctgaccg ccgtaatggt ctgggttatt
    29641 tggggcgtga tcgttaatgc ctggtttatt cctgaaattg ccagccagtt cttcaccatg
    29701 ggtctggtga ttggcatcat cggcgttgtt ttccgcctta acggcatgac ggttaatacc
    29761 atggcttcat cctttaccga aggggcgcga atgatgatcg cccctgccct gctggtgggt
    29821 ttcgccaaag ggattttgct gctggtcggt aatggtgaag cgggtgatgc cagcgtgtta
    29881 aataccatcc tcaacagcat tgccaatgcc attagcggtc tggataacgc agtcgcggcc
    29941 tggtttatgt tgctcttcca ggcggtattt aatttcttcg tgacgtccgg ttctggtcag
    30001 gcggcgttaa ccatgccgtt actggcaccg cttggcgatc tggtcggtgt taaccgtcag
    30061 gttaccgtgc tggcgttcca gtttggtgat ggcttcagcc acatcattta cccaacctca
    30121 gcttcgttaa tggcgacgct cggtgtttgc cgggtggact tccgtaactg gctgaaggtg
    30181 ggtgcgaccc tgcttggact gctgtttatt atgtccagcg tcgtggtgat cggcgctcag
    30241 ttgatgggct accactaaaa atgttaagag ccgcgattgc ggctcttttt tcattctgcc
    30301 gtttcagtct cgacggcttc atttttggca ttgcgcttca tccacaacgc cagcgctttc
    30361 agcgagtctg gagtgaactc atcgcagcgt gcggtgattt cttccggcgt cagccagcaa
    30421 acttcactga cttcatcttc ctgtagagcg aagggaccgt gagagacgca gctgaacaac
    30481 gcgccccaga cacggcaatt tttatcttcg aaatagaact gcccgtgctc ggcaaagggg
    30541 acaccggcaa tgcccaactc ttcttccgct tcgcgacgcg cggattccag cagctgctca
    30601 tcggcctgga ctacaccgcc tgcggtcgca tctaacatgc cgggtaaaaa gtcttttgtc
    30661 tcggtacgac gctggaccag aattttgccc atgccatcat gcacgacgat ataagttgca
    30721 cgatgacgca gacactgtgc ccgcatttgt tcccggctgg cttgtgcaat gacttcgttc
    30781 tcttcattga caatatccac ccattcagta cttgccaaac gacgctgttc cattatcagg
    30841 aaaccttctt tttctggcgc tcttacggcg cattttgagt tgtgggtaaa ttacggatta
    30901 atcgcgacct gcgcaatgat actttgatca ttgagtgcga ttacactaag tacgtcatta
    30961 tccagcatgc cataactcgc cggattaccg cctttcggaa tactcaccga gccggggttg
    31021 aagtggaaaa tctccccccg ctgttctgcc actggcagat gggtatgacc gtacaccagc
    31081 acatcgttct ggtttaaagc aggtagattt tccgggccaa aaagatgacc atgcgtcaaa
    31141 aacagacgtt gtttttccag taatacctgt tgccacggcg cggttatcgg gaaatgcagc
    31201 agcatttgat ccacttcgct gtcgcagttg ccgcgcacag cgataacctt atgtgccact
    31261 tcattaagcc gttcagcgac tttggctggc gcgtaaccct ccggtaaagc attacgcggg
    31321 ccatgattca acacgtcgcc aaggatcacc agccactggg caccgctttg ggcaaacaac
    31381 tccagaacac gttccgtcgc cggtaacgac ccatgaatgt ccgatgcaaa catcagtttc
    31441 atcactcact cctcgtcgaa aaaacgtaag ctatgatact ggattctgtc gttgctatca
    31501 gccagattgc ttcgccgaaa gtgcaataaa acgctggaca gacgctcgct gccactggaa
    31561 tgtcgcataa tccaccaggc gttccggcac ctcatcgcca tgtagtacca ggcggttaat
    31621 cattagcgcc agatcagtat cagcaatgca ccattcacca aataaattcg gctgacccag
    31681 tgctaacaaa tgctctgcca tcgcgaacag tttctctgca ctggcttttc cctcggccgt
    31741 tagtggcgct tttttcgccc ccgcaaagac aacatccgtc gggcgttctt cgcggatggg
    31801 catcagatcg ctgcgcagcc aggcctgaat ctgtcgtgca cgcgcacgat tttctaaatc
    31861 aagcggataa atacgttccc aggtcggtgg cgcaaatcga tcttccagat actccgcaat
    31921 ggcagaagat tcactcaact caaaatcatc gatttgtaat aacggcacac ggcgtgtctg
    31981 accgtaacct tgccacgtcg gctgcaaatg ttcaccgctg tcgaggtcga tggtcttgat
    32041 atgaaacgac aggcctttct cctgcaacgc cacccaggcg gataacacat aaggggagaa
    32101 aaaatgggca tctgaccaaa gcgtaatagc gggtttactc attatgtcct cggcaataaa
    32161 gggggcttgc tatcaaacta tagagccttt ttgtcactgt cacgtgacga atactcacgc
    32221 aagtcgccgc gctttctata cttgtggtgt tcagatgatt agacaaccgg agctgcaatg
    32281 atcgatctct atttcgcccc gacacccaat ggtcacaaaa ttacgctgtt tctcgaagaa
    32341 gcagggctgg attatcgctt gataaaggta gacctgggga aaggaggtca gtttcgcccg
    32401 gaatttttgc gcatttcgcc taacaacaaa attccggcaa ttgttgatca ttctccagcc
    32461 gatggcggcg aaccgctaag cctctttgag tctggtgcca ttttgttgta tctggctgag
    32521 aaaacgggac tctttttgaa tcatgaaacg cgtgaacgcg ccgtcacatt acagtggtta
    32581 ttctggcagg taggcggact ggggccgatg cttgggcaaa atcatcattt taatcacgca
    32641 gccccccaaa ccattcctta cgctattgaa cgttatcagg ttgaaactca gcgtctgtac
    32701 catgtactga acaagcggct ggaaaattcg ccctggctgg gaggcgagaa ctacagcatt
    32761 gcggatattg cctgctggcc gtgggttaat gcctggactc gccagcgaat tgacctcgca
    32821 atgtatccgg cagtcaagaa ctggcatgag cggatccgtt cgcgccctgc caccgggcag
    32881 gcactgctaa aagcacaaca cggtgatgag cgttcggata gttaacagaa acaggttctc
    32941 gtgtattatt tcattctaag taaaacaacg gagaacctgc aatggcacaa cctgccgcta
    33001 ttattcgtat aaagaacctt cgtttacgta cgtttatcgg aattaaggaa gaagaaatta
    33061 acaaccgtca ggatattgtt atcaatgtga cgatccacta ccccgccgat aaagcgcgca
    33121 ctagcgaaga tatcaacgat gcgctgaatt atcgcaccgt aacgaaaaac attattcagc
    33181 atgtagagaa taaccgtttc tctttgctgg aaaaattaac tcaggatgtg ctcgatatcg
    33241 cacgcgaaca tcactgggtg acgtatgctg aagtggagat cgataaactg cacgcgctgc
    33301 gctacaccga ttcggtatcc atgaccttaa gctggcagcg ttaaccacca tatcgggagg
    33361 ctgcatgaac atagtgatca ccggagggac gggattaatt ggtcgccatt tgattccacg
    33421 tttgctggac ctgggccatc aaatcacggt agtgacgcgt aacccgcaga aagccagttc
    33481 cgttctcggc ccccgagtga cactatggca agggcttgcc gaacaaagca acctcaacgg
    33541 cgttgatgcg gtaatcaacc tggccggaga accgattgct gataaacgct ggactcacga
    33601 gcgaaaagag cgtctctgcc aaagccgctg gaataccacg caaaaactgg tcgatttgat
    33661 taatgccagc gacacgccac cgtcggtact catttccggc tcggcaacgg gctattatgg
    33721 cgacttaggt gaagtggtgg ttaccgaaga ggaaccgccg cataacgaat ttacccataa
    33781 actctgcgcc cgctgggaag agattgcctg tcgggcgcaa agtgacaaaa cgcgagtgtg
    33841 cctgctgcgt accggcgtag tgctggcacc agacggtggt atcctcggta aaatgctgcc
    33901 gccatttcgt tttggcctgg gcgggccgat tggctccggt cggcagtatc tggcctggat
    33961 tcatattgat gatatggtca acggcattct ctggctgctg gataacgagc tgcgcgggcc
    34021 atttaatatg gtttcgccct acccggtacg caatgaacaa tttgcccatg cgctcggtca
    34081 tgcgctgcat cgcccgacca ttttgcgcgt ccccgcgacc gccattcgac tgttaatggg
    34141 cgaatcttca gtactggtat taggtggaca acgcgcgctg ccaaaaaagc tggaagaagc
    34201 gggttttgcg tttcgctggt acgatttaga agaggcgctg gcggatgtcg ttcgctgatg
    34261 tggtttactg caaacatccg ccagcggaaa cgctgatgaa taaatataga taattcagaa
    34321 ctatttttag cggactgcaa cttttacatt tcagcggaag cggactcgca aattccccat
    34381 gaaatactcc ggcagcgtta accaccggag aggaaattat ttcagcgaac ctttaaggaa
    34441 ctgttgcaga cgagggcttt gcgggttacc gaataactgc tccggcgccc cttcttcttc
    34501 tattttcccc tgatggagga aaatgacgtg agtagaaaca tgacgagcaa agcccatttc
    34561 gtgagtcact accaccatgg ttttcccctc ttctgccagt tgctgcataa tacgcaacac
    34621 ttcgcctacc agttcaggat cgagcgctga agtaggttca tcaaacagta aaacttccgg
    34681 ttccatcgct agcgcccgcg cgatagaaac acgctgttgc tgaccaccgg acaggtgcac
    34741 cgggtatttc ccctgcgcac gttcgtctat cccgactttt gccagatact tcaccgcccg
    34801 ctcgcgcgct tcctgcttgc tcaggcccaa cacctgaatc ggcgcttcca tgacgttttc
    34861 cagcaccgtc atatggctcc agagattgaa gtgctgaaat accatcgtca ggcgtgtgcg
    34921 caataagcgc agctgatttt tatcggcgac tttgagttga ccatctttat cgcgcaccag
    34981 attgatcgtc tggccattga ccacgatcga tccatcgctc ggtttttcga ggaagttaat
    35041 gcagcgcaga aaggtacttt tccccgatcc cgacgatccg atgatgctta tgacatctcc
    35101 ggcattcgct tgcaatgaga cccctttcag cacttcgtgt tcgccgtagc gtttgtgcaa
    35161 atcgataacg tttaatttat tctcggacat cgtattctca gtgcgttgaa gaaggtttca
    35221 catgctgcaa ccagcgtttt tcagctctac gaaagaggct gatcagaaca taagagatga
    35281 ttaaatagag caccgcggca atgccgaaag cggtaaaagg ttgatatgtg gcggcgttaa
    35341 tatcgcgggc aattttcagc agatccggca ccgtggcagt aaatgccagc gcagtagagt
    35401 gcagcatcag gatcacttcg ttgctgtatg ccggtaacgc aatacgcagc gcagaaggca
    35461 aaataatgca gcgatacatt ttaaaggtcg agaagccata ggctctggcg gcttcaattt
    35521 ccccatgcgg cactgaacgg attgccccgg caaaaatctc ggtagtgtaa gcgcaggtgt
    35581 taagcgtcag cgccagcacg gtacagttca ggccactgcg aaaaaaggcg ttaaggaact
    35641 cggttccctt aacaatctcc agcgtgtaca tgccggaata gaacaccagc aactgaacat
    35701 acagcggcgt accgcgaaaa atataggtaa ataaccagat tggaaactgg atgtatttat
    35761 tacttgagac gcgaccaatc gccagaaaca gcgccagaac tccgcctatc actaccgaca
    35821 aaatcagcag ccacagggtg atcgccacgc cagtaaagcg ataaccgtca gtccacagca
    35881 gtggtttcca gtattcatgt aagatttcga tcacaggtca gccctcttca cacccacgga
    35941 gtagcggcgc tcaaggaaca gcagcacacc attggaaacg gtggtgaaaa caagataaat
    36001 cacgccgcag acgatagcga aatagaacgg ttcccaggta cttttgcctg ccagctgcgt
    36061 ggctttgacc acatcttcca ggccgagtaa cgaaaccagt gcggtagatt tgaggatcac
    36121 ctgccagttg ttgccaatgc ctggcagggc gtaacgcatc atcgccggaa acatgatccg
    36181 ccgaaacact tgcccacgag taaaaccgaa cgccgtcgcc gcctctatat gtcctttcgg
    36241 cactgccata aacgcgccac gaaacgtttc ggtaaaataa gcaccgtaga taaaaccgag
    36301 agtgataata cctgcgacca tcggatcaat atcaatctgc ccgacgccca tcgcctccgt
    36361 caccgtgttt agcgcaatct gcaaaccgta gaaaatcagc agcatcaata ctaaatccgg
    36421 cacgcctcga atcagcgtgg tgtacccttc gaaaataagg cccgaaagcc gattttgtga
    36481 gagcttaccg ccagcgccaa ttaaaccgat gattacagcg agcactacag agctgatagc
    36541 cagctccagc gtgacgagcg caccctgtaa aataacactt gaaaacccat acaacatgct
    36601 gcctgtcctg tcgtgtgtgg tgaattaccg cctcttgtct ccctccggtt acccgaaggg
    36661 agcgggcttt ctttcaccga tggcgattaa ccaccataaa catcaaaatc gaagtacttt
    36721 ttcgctaatt tctcgtaagt accgtcagcg cgcatttcgg caaaggcttt gttcagtgcc
    36781 tcgcgcagtt cgttatcttc tttacgcagg cccatgccgg tccctacgcc aaacagtttt
    36841 tcatctttaa cagacgggcc accgaatttg taatctttac cgacgggttg tttgaggaaa
    36901 ccttcgctgg ctgcgacctc atcctggaac gcggcatcaa tacgtccggc agtcaggtca
    36961 gaataaatgt tgtcctgccc ctgataagaa acgatttcaa tgccttttgg tgcccagtgt
    37021 tcgttaccga acgtctcctg ggtggtgccc tgcaatacgc ctacccgttt gcctttcagc
    37081 gattcgactg tcggctgaat gtcggaattt ttcgccacca ccagacgaga atcggctgcg
    37141 tacagtttgt cggtgaaggc tatttcttgc tgacgttttt ccgtaatgga aagcgatgac
    37201 atgatggcgt caatcttctt cgcttttaag gacgggatta acgcatccag tgggttttcg
    37261 acaaacgtac attgcgtatt gatgcgtttg cacaactcct tggccagatc gatatcgaag
    37321 ccaaccagtt caccttgtga attttttgat tcaaatggcg cataggtcgg atcggtaccg
    37381 atgcggatgt tttgcggaat cgcagcaaat gctgcagttg cgctggagaa ggccagaacc
    37441 agagagagcg atagcaccag ttttttcata atgtcctcaa ctgacagtct ttttatcggg
    37501 aatatttaca ggtttgttac acttatcgtg ccataaaatt gaccatcaag gcaaaatatc
    37561 ccgccccgct agacgtatta tttttcatta aaaatgctta agtatgcatt tcaatgcacc
    37621 acgatagtgc aacaaacctg gcgtgcacca tgatgatcat tccatcaggt acagcttccc
    37681 tgcgacgtat cagtcaccgt agacattaaa gtcaaaatac tttttcgcca tcttgtcgta
    37741 ggtgccgtcc tgacgcagct cgccaagcgc cttattaaac gcagccgtca gttccgcatc
    37801 atctttacgt agccctacac cggtgccgtc accgaagtat tttttgtctt tcactgatgg
    37861 gcctgcaaag gcgaaatctt taccggcggg ttgcttaagg aaaccttcgc tggcagcaac
    37921 ttcatcttgt aacgcagcat ccagacgtcc tgcagccaga tcggaataga ctaaatcctg
    37981 gttggcatag gccaccacat ccacgccttt gctacgccag gtctcgttag cgtaagcttc
    38041 ctgggttgat ccctgcagca caccaacatg tttacctttc agtgaatcca gcgttggctg
    38101 aatcggtgaa cctttggcgg caatcaaacg agaatctgcg gcgtacagct tgtcggagaa
    38161 agcaatctcc tgctgacgtt tatcggtaat ggagagcgac gaaataatgg cgtcgatttt
    38221 tttcgctttc agtgagggga tcagcgcgtc aaagtcgctg gcaacccagg tacatttcac
    38281 ctgcatccgt ttgcacatct cgttaccgag atcgatatca aagccaacaa agtcaccttt
    38341 ggcatctttc gatgagaacg gtgcgtaggt ggtatcggtt ccgatacgta ccgtctccgg
    38401 tagcgccgca tagctggaag ccgctgcgga gagaccgact aacaaagaca gagcgagaat
    38461 cgacttcttc atacataacc ctcaagtgaa aatggctttt ttatgttgtg tattgtgttg
    38521 tgtgtttgca ggctctttca tgcaggtctt atgccatctt gacgacagca gtaacattca
    38581 acgttaaata tgttaataag aagttgcatt attgtcctaa agttgaagat agcaggtata
    38641 gcggttgaat cgcagcgttt cgattgaatg gcagaaacaa aatgtcgagg atttgatcgc
    38701 ggttgcaaaa ttgccctgaa acagggcaac agcggagtta tgcgccctgc cagcgggcaa
    38761 agagatcttc aggaagggtt accgcaaact ggtcaagaac acgattaacc gtctgattta
    38821 tcacatcatc aagggattgt gggcgatgat aaaacgccgg aacgggaggc ataatcaccg
    38881 caccgatttc tgccgcctga gtcattaaac gcagatggcc taagtgcagt ggcgtttcac
    38941 gcacgcagag caccaacggg cgacgctctt tcagcaccac atctgccgca cgggtcagta
    39001 agccatcagt atagctatgg acaatgccgg acagggtttt gattgaacag ggtaaaatca
    39061 ccatccccaa cgtctggaaa gaaccggaag aaatgctggc agcaatatcg cgcgcatcgt
    39121 gtgtcacatc agctaacgcc tgcacttcgc gcagggaaaa atccgtttcg agggataagg
    39181 tctggcgcgc cgcctggctc attaccagat gcgtttcgat atctgtgaca tcgcgcagaa
    39241 cctgtaataa acgcacgcca taaatcgcgc cgctggcacc gctgatgcct acaatgagtc
    39301 gtttcataaa tagttgccct gtcagacttg caggcagact ttgcaggatt tcggcgggag
    39361 ttgcaagtca gggtgccaga ccggcaccct gagcgaaggc atcatccttc gttatgcatt
    39421 tcgagatttt ccacttcgtt ctgacgttgc actgctttgg cgtcgtcatt acgtaaagta
    39481 tcgaggaaat cgaggtagcc ctgatcaacg tctttggtga cgtagacgcc gttgaacacc
    39541 gagcattcaa actgctggat atccgggttt tcagcgcgaa cggcttcgat cagatcgttc
    39601 agatcctgga aaatcaaccc gtcagcaccg atgatctggc gaatttcatc tacttcgcga
    39661 ccgtgagcga tcagttccgt ggcgctcggc atatcgatac cgtaaacgtt cgggaagcga
    39721 atttccggtg ccgcagaagc gaggtacact ttcttcgctc cggcttcgcg tgccatctcg
    39781 ataatctgct cagaagtggt gccacggacg atagagtcgt cgaccagcag gacgttttta
    39841 tcgcggaact cggcgcggtt ggcgttcagt ttacggcgca cggacttacg acgcagctgc
    39901 tgacccggca tgatgaaggt gcggccaaca tagcggtttt taacgaagcc ctggcggtac
    39961 ggtttgccca gaatacgcgc aatttccagc gcgatatcgc aggaagtttc cgggatcggg
    40021 atcaccacgt cgatatccag atcttcccat tcgcgggcaa ttttctcgcc cagcttcgtg
    40081 cccatattca cacgcgcgct gtaaacggaa attttgtcga tgaacgagtc cgggcgagca
    40141 aagtatacat actcaaacag gcacggattg ctgaccggat tgtcagcaca ctgacgggta
    40201 aacaactgcc cttcttcagt gatgtaaatc gcttcgccag gggcgacatc acgcaggaac
    40261 tcaaagccca gcgtatcgag cgcaacgctt tcggaagcga ccatatattc tgtgcgatta
    40321 tcgtcaatat cacgtttgcc cagtacaagc ggacgaatcc cgttaggatc gcggaaagca
    40381 accataccgt ggccgataat catcaccaca caggcatacg cgccgcggat taagcggttt
    40441 gtagcagcga tggcggcgaa aatgttgtcg gcttccagcg ggtagtggcg gaagttgtcc
    40501 agctcgctgg cgaagatatt aagcagaatt tccgagtcgg aagtggtgtt gatgtggcgg
    40561 cgtttttctt caaacagttt tttacgcaac tcgtgagcgt tggtcagatt gccgttgtgg
    40621 gcaagcgtaa tgccatacgg agagttaacg taaaacggct gcgcttcaga ggcgctggag
    40681 ctgccagccg tagggtaacg cacatgacca atgcccatat tgccctgcaa acgctgcata
    40741 tggcgagctt caaatacatc gctcaccagc ccgttcgctt tccgcaaacg gaagcagtta
    40801 ttggcatcta tggtgatgat gccggcggca tcctgaccgc gatgctgaag caccgttaag
    40861 gcatcataaa tcgactggtt aaccggcata acaccggcga taccgacaat accgcacata
    40921 cgtctttttc ctcgttaagc cacatctcag agcacttacg ctctgggcaa gaaacttgac
    40981 gagctttgca gataatcaaa aaaccatctg atgataaaac tgaactgcgg gatcagctgt
    41041 gatttgctcc agtcttcgct tttcgacacc ccggtaaagg agtcgagaaa gaagagaatg
    41101 gcagcaacaa tcaacacacc gcgcaaggca ccgaaacaga cgcccaacac ccgatcggtg
    41161 cctgacaacc ccgttttctc caccaactgg cctatcacga agttcacgat agcaccaacg
    41221 atcagggtag cgataaacag taccgcgatg gcaatcccat ttcgaaccag ttcgtcttca
    41281 aagcccgtaa accagactga caggtaagtg tagtaatgac tggcaacaaa gaaagcacaa
    41341 ccccatgtca ccagcgataa cgcttcacga acaaagccgc ggatcaggct aaccagagag
    41401 gaaaaagcaa tcaccgcgat tatggcgtaa tcaatccaga ccatatgtgt cccacgattt
    41461 tacgccctgt catcctgttc ggggcgcatt ctaacagaaa aagaaaacgt ttgcgtaggg
    41521 atttccttcc cgcgcatcaa taaaaatggc gctgaaaaaa tattcaacgc catcgacttt
    41581 ttatgccttt gcggcatcgg gcaatgcgtg tcggatgcgg cgtgaacgcc ttatccgacc
    41641 tacggctcta cccctgcaca ggcctgataa gacgcactgg cgtcacatca ggcaacggct
    41701 gtcggatgca gcgtgaacgc cttatccgac ctacggttct acccctgcac aggcctgata
    41761 agacgcgctg gcgtcgcatc aggcaacggc tgtcggatgc ggcgtgaacg ccttatccga
    41821 cctacggttc tacccctgca caggcctgat aagatgcgcc agcgtcgcat caggcaaaac
    41881 cgtattaatt cggtgtatag cccattacca caccacttaa gccagaaagc tgcttgagct
    41941 cacccagcga tcctttcagc ttctctttgg aagcatctgg cccaaccaga atacgggtaa
    42001 ttttaccctg cactggcgtg gatggcgacg tataaacccg ataaccggca ccgcgcagct
    42061 taccgacaat ctcattcact ttatcggcat ttttcagcgc gcccagttgc acaacatagg
    42121 ctttacccgt tggcgctgct ttttcttcca cgaccggctt cggttctggc ttcggcgcag
    42181 gtggtgcttc aaccttcggt ttaggcgact ccaccggttt cggcttcggt gggacgaccg
    42241 gtgcaggttc cggttcaaac tcggtgttat tggctgcaat agtggccgga tcgagcgacg
    42301 gtgctgcggc atcgcctgcc cgcacctctt ccgctgcgcc ttccggcggc tgcgtcggca
    42361 acgcctgggt ggcggctggc atcatatcag gctcatcgcg atcgcccgct ttcggcacca
    42421 gcgggatagc cgcgaactca tcctgataat gttttttctg cccgtccagc agccctggaa
    42481 gtacaatcac ccccagcgcc accagcacga tcgtgcccac taaccgattc tgaaacttac
    42541 ttgccaccgc ttctcctcgc gtcaatcact tccatgacat gtgcgaccgt gtggaacgaa
    42601 ccacacacca gcacggtgtc ttccgcttta gcgtccgcca ttgcggcatc ccatgcctgc
    42661 gcaacgctat caaatgattt gccgttaccc aaatgctcaa gcagttgttc tgccgtggca
    42721 ccgcgcggcc cttccagtgg cgcacaatac cagtcatcaa ccacgctttt caaccaggcc
    42781 agagttccgg caatatcttt atcatgtagc ataccgataa ccgccagcac gcgcccgttt
    42841 ttcggtagcg ctttcatacg cccggtgaga tattccgccg catgtggatt atgcgcgaca
    42901 tcaaaaataa cgcgtggcga ctcgctcaca atctggaaac gtcccggcaa aattgcgctg
    42961 gcaatcccgt cgcgaatggc attttcactg acctccagcc cgctggcacg cagtgccgcc
    43021 agcgccgttg cggcattcgg ttgcgggaca agcggcaacg gcagattttc cagcgtgccg
    43081 tgagcatcgc taaacgtcca gtcatgatcg gtgacggaat agttccactc aacgccccga
    43141 cgttgtagca gtgcaccttt ttcctgcccc acatcagcaa tggtagaagg catttccggc
    43201 tcaccgacaa ttgccggttt ttcgctgcga aagatacctg ctttctcgcg accaatactt
    43261 tcgcgatctg gccccagcca gtcggtatga tccagcgcaa tactggttac taccgcgaca
    43321 tcggcatcga caatattggt tgcgtccaga cgaccgccca gccctacttc cagaatcact
    43381 acgtcaagtt gtgcctgctt gaacagccac aatgccgaca gcgtaccgta ctcgaaatag
    43441 gtcagggaaa tatcaccgcg tgccgattca atctccgcaa aagaagcggt gtgggccgat
    43501 tccggcaatt cctgcccctg cacacgtacg cgctcggtat aacgcaccag atgcggcgaa
    43561 ctgtagacgc ccactttgta ccctgccgcc atcagaatcg actccagcgt acggcaggtg
    43621 gtgcctttgc cattcgtacc cgcaacggta aacacaaatg gcgctggttt cagaacgcca
    43681 agacgcgccg cgacctggct cacgcgctca aggccgagat cgatagtttt actgtgcagg
    43741 ttttccagat aagaaagcca cgaagccaga ggcgacgcgg cttgaggagt gcgtttgata
    43801 atcatggtat ccgctgattc gttacggtga gaatagcaaa agggcagagc cagtggccct
    43861 gcccttatca gttatcaggc ctcaggttcc tgatccggta ccggtggcac cactacgcct
    43921 tcacgcggcg cttcaggatt cggcgctggc agattcatca acttcgccag aatgctcgcc
    43981 agtttcagac gcatttccgg acgacggacg atcatgtcga tcgcgccttt ctcgatcagg
    44041 aattcactgc gctggaatcc tggcggcagt ttttcgcgaa cagtctgttc gataacacgc
    44101 ggaccggcaa agccaattaa cgctttcggt tcagcgatgt tgagatcgcc cagcatggcg
    44161 aaacttgcag aaacaccgcc catggtcggg tcggtcagca cggagatgta cggcaagccg
    44221 cgctcctgca tttttgccag tgccgcagag gttttcgcca tctgcatcag cgacatcagt
    44281 gcttcctgca tacgtgcgcc accagaggcg gagaagcaga tcagtgggca gttatcttcc
    44341 agcgcctgct caacggcacg cacgaaacgc gcacctacca cagaccccat ggaaccgccc
    44401 ataaaggcga actcgaatgc cgcagcgaca accggcattc catacagagt gcctttcatc
    44461 accaccagcg catctttttc gccggtttct ttctgcgcag atgccagacg gtctttatac
    44521 ttcttggagt cacgaaactt cagcacatct ttcggctcaa gctcgctacc cagctccaca
    44581 aggcttcctt catctaacag gctatgcagg cgattacgcg ctgtcatacg catgtgatgg
    44641 tcacacttcg gacagacctc aagattacgt tccagctcag cgcggtataa aacctgaccg
    44701 cagctatcac acttagtcca caccccttca ggaatgctcg ccttgcgggt gggagtaatg
    44761 ttgcttttaa ttcgttcaat ccagctcatt agggaccttt ctgtctgaac ctggttcgat
    44821 gccagtttta tctttgggga cgcataatgc catttttgcc cccaacagac catgaatgtt
    44881 gcacattaaa acataacagc ccgaaacttt ggataaaaaa gtggtcgaac cgcagagtta
    44941 ctttttattt tgcggcgcgt gccgctgcgc gtttgtggcg aataaattcg aaaacacctg
    45001 gcaatattga aacaaaaata atgccaacaa tcatcagttt aaggttgctc tgaatgaagg
    45061 ggagcgtgcc gaagaaatag cctgcgtagg taaaaagcag tacccacaac agtgcgccaa
    45121 tcacgttata agcggcgaaa tgacggtacg acatgtggcc cattcccgca acaaacgggg
    45181 cgaacgttct gacgatcggc acaaaacggg cgagaataat cgttttgccg ccatgtttct
    45241 cataaaactg atgggttttg tcgagataac tgcgacggaa aattttcgaa ttgggattac
    45301 tgaataactt ttcaccgaac aaccgcccga tagtgtaatt gaccgcgtca cccacaatcg
    45361 cggcgatcag catcagcacc accatcatat ggacgttgag atcgttggtc tccagtgatg
    45421 ccaacgctcc ggcaacaaac agcaatgaat cacccggtaa aaacggcgtt accaccagac
    45481 cggtttcaca gaacaaaatt aagaacaaaa tggcataaac ccagacgccg tactccgcga
    45541 ccagctctgc cagatgcacg tcaatgtgca ggataaaatc gatgaggaaa taaatcaggt
    45601 ccatatttgc ctatgccttg tactcgtcat ctatcaggct gtaactacgt tggctacagc
    45661 ctgaaatgtt ccgagcatta ttctcgttag tccgccagaa atagcgggcc cattggcggt
    45721 tttggaagat catatcggtc agggtaatcc accgcgacca gatatagccc ttccgctttt
    45781 gccgttgctg ccgccagcgt tctgtccttt gccgccagca actctgctat ccagctctcc
    45841 ggctggttgt gggcaccgac ttccatcagg ctgccgacaa tattcctgac catatgatgt
    45901 acaaaggcat tcgctttgat atctaccacc acataaggac cgtgacgcgt gacattaata
    45961 tgcataacgt tgcgccacgg ggtccgggac tggcactgca ccgcacggaa cgaggtgaaa
    46021 tcattctcgc ccagcaaaca ttgcgcagcc cgatgcatcc gttcagcgtc cagcggttcg
    46081 taaaaatggg ttaccccttt actcagtacc gccgggcgca gccgatgatt gtagatgatg
    46141 tagcgataac ggcgagccgt ggcgctaaat cgggcatgaa aatcatcagg tacagcttta
    46201 acccaacgca cggcgatgtc accaggtaaa ttcgcattta cgcccaacgt ccacgcagcg
    46261 tctttgcgct gcgcggtcgt ttcgaaatgc acaacctgcc cggtaccgtg tacaccggcg
    46321 tcagtacgcc cggcgcagaa gacggtgatg ggttcgttcg ccacctggga gagcgccttt
    46381 tccagcttct cctgcacact gcggacttca ttctgccgtt gccagccgta atacctactg
    46441 ccgtcgtact caatgcccag cgcaatttta taaactggcg gttgttgctg gtcggacatt
    46501 agtacagata ctcctgcacc agtttctcgg caatttttac tgccatcagc gcgccgccaa
    46561 agcgaacgtt atcggccacc gaccagaact gaacttgctc cggcataccg tagtcattac
    46621 gtacgcagcc aacagaaaga tgcggcgtac cagaagcatc ccctacctga gtcgggaatt
    46681 cgttctcttc agagagcaca atatcttcgc cctgagcaaa cgcatcacgc gcttcttctg
    46741 ccgccagcgg acgcagtgct tcaaagttga ccatctgggc atgaccgtag aataccggtg
    46801 cctggacgac gcttgccgaa atcatcagcc cttcgtcctg caggattttg cgtacttcgt
    46861 caacgatacg acgttcttca cgcacgctac cttcgctatc cggcagtaac ggcagcatgt
    46921 tgaacgccag ctgacgcccg aagaaatctt cttcgtcaat cggaatgcca ttgagtaatt
    46981 tagcactctg ccccgctaac gcatcgaccg cttttttgcc ctgggcggag gctgaaatca
    47041 ggctggtaac gctgatacgt gataaaccgc cctgatcaat tagcggtttc agtgccgcca
    47101 gcagctggct ggtcagactg tctggtacgg cgatgacatt ccggttgcgg taatcggtca
    47161 gtacaaacgg gtttacttcc ggcaccacca gcggtacgtc gggttcgaga gcaaacaatc
    47221 cgctgctgtc gatcaccaga caacctgagt tggtcgcttc ttcaacccag gcagcggtag
    47281 cctctttgcc tgcgacaaaa aatgccagct gcgcctgcgt ccagtcgaat tcagcagcat
    47341 cctgcacggt gattgtctta ccaccaaagc gcagttgttc gcctgcgctt tcgttacgtg
    47401 ccagtgcata aatttcccca accgggaact gacgttcagc cagcgtttca agcagggctt
    47461 cgcccacagc gccagttgcg cccaggacgg caatgttcca gccttcagac atggtggttt
    47521 actccagaaa tagcaaagct ccctgccaat attacagcag agagcatgaa gaagagatta
    47581 acgtgccgga tgatgaacgg cgttaaaacc cagtttacac agcaatgatg ccgcgctggc
    47641 gtcatcacaa atcacataca gagatgacca ttcacggcgc tcaagatagt ttttgcgcag
    47701 cttatcgaac tcacccggta ttccggcgac tttacgcagc ggtgcgtcat cgcggcgcac
    47761 atcatacacc aaatgcacca gcctttttag cgtcggttga tcgagcggac catgcagcgt
    47821 aatgcggcca aactctggcg cgggcagcaa cgtatccagc gcaacgtgtt gttcatgccc
    47881 aataagcttg ctataggctt caaacacttg cgtagtaccg cgtgctttac cttccagggt
    47941 atagcctgcg atatgcggtg tgccgatatc cacttttttc agcaattcca cgttgagttc
    48001 cggttcgcct tcccagacat ccagcactac gcttaacttc tggccttcgt tcagacaggt
    48061 caatagggca gtattatcga cgactgcgcc acggcaggcg ttaatcagaa tcgctcctgg
    48121 tttcaggcta cggatcagtt tttcatccgc cagatgcagc gttttgtacg gcccgtcttt
    48181 gaagagtggc gtatggaaag tcagaatatc cgcatgctga actaattcat ccagcgagcg
    48241 gaaatccccc tcatccccgc ggtcggcgcg aggcggatcg caaagcaagg ttgtaatccc
    48301 taacgcttcc agtcgcgcct gtaaacggcg accaacgtta ccaacgccca cgatccccac
    48361 tgtacggtcg tgcagtgaaa atccatcgcg ttcggcaagc atcagcagtg aggagaaaac
    48421 atattccacc accgcaatcg cattacagcc aggtgcagcg gaaaaaccaa ttcccgcctg
    48481 ctttaaccat gcttcatcga catggtcggt ccccgcggtg gcagtgccaa caaatttaat
    48541 gggttttcct gccagcaaag attcattcac tttcgtgacc gaacgcacca taagcgcatc
    48601 cgcgtctgcc agttgagcga caggaattgg acgcccggga accgcggtca cctcacccaa
    48661 acggctaaat aagtcgcggg cataaggcat attttcatca acaaggattt tcacgtttgt
    48721 gttacctgta tgagacgaga gttaaccaga caagtgtgcc ataatctcgc ggccaggcat
    48781 acttgcgaag atttcaggta taaggatacg taatgataca acctatttcc ggccctcctc
    48841 ctgggcaacc accaggccag ggagataacc tgccgtctgg cgcgggcaat cagcctttat
    48901 ccagtcagca acgtacttcg ctggaaagct taatgacgaa agtgacctca ctgacgcaac
    48961 aacaaagagc agaactgtgg gcgggtatca ggcacgatat tggtctgtcg ggagattcac
    49021 cgctgctttc gcgtcacttc cctgccgctg agcacaatct ggcgcaacgt ctgctggccg
    49081 cgcaaaaaag ccattctgcc cgccagcttt tagcgcaatt aggggagtat ttacgtctgg
    49141 ggaataatcg tcaggcggtc acggattata tccgtcataa ctttggtcag acgccgctga
    49201 atcagctctc accggagcaa ttaaagacca ttctcaccct gttgcaggaa gggaagatgg
    49261 ttattccgca acctcagcag cgcgaggcga ccgaccgtcc gttattaccg gcggagcaca
    49321 atgcgctcaa acagctggtg accaaacttg cggcggcaac gggagaaccc agcaagcaga
    49381 tctggcaatc gatgctggaa ctttccgggg tgaaagatgg cgagttaatt ccagcgaaac
    49441 tgtttaacca tctggtgacc tggctacagg cgcgtcagac gctaagccag caaaatacgc
    49501 cgacgctgga atcactccag atggcgctaa aacaaccttt agatgccagt gaactggcgg
    49561 cgttatcggc atatatccag caaaaatatg gcctttctgc gcaatcatcg ctttcttctg
    49621 cccaggccga ggatattctt aatcagcttt atcaacggcg ggttaaaggg attgagccgc
    49681 gtgatatgca accgctgctt aatccttttc caccgatgat ggacacgttg caaaatatgg
    49741 caacgcgtcc cgcgctgtgg atactgttag tcgcgattat cctgatgctg gtctggctgg
    49801 ttcgttagcc ccgacgaaat gacagtatcg tgacaataat tcccagcacc gcagagatcg
    49861 ccccggcaag aaataccgaa gagtaaccaa acgtggtcgc cagcattccc gccagcggcc
    49921 cggagacgcc gagggcgata tcctgaaacg cggcgtaacc gcccagtgcg gtgccgcgaa
    49981 cttgtgaggg gacgcgttta accacctcca cgcccagcgc aggaaagata agcgaacatc
    50041 cggctccggt taacgccgcg cccgctaatg cgacccacgc accaggggct tgccagagca
    50101 gcaacaagcc caccgtttct acaagcagag agacgatcgc cactttcacg ccgccaaaac
    50161 ggtccggcat ccagccaaac atgacgcgca tcacgacaaa tgcgccgcca aacgcggtaa
    50221 gagtaaagcc cgccatcgcc catcctttac tggcaaagta gagcgaaacg aaagtcccga
    50281 taaccgcaaa accaacgcct tgtagtgcca gacctaaccc tggtttccag ataagcccga
    50341 caacgctcca cagcgatgga cgttctcccg ccagggccgg tactttgcgc actgtgccgt
    50401 tacaggccca cgccagtaag ggtaatgcca ttgtggtgag cgccagtgcg gcaaaaccgt
    50461 aatggctatg aatcaacagg ccaagcggcg caccaacagc gagggcaccg taaatcgcca
    50521 ttccgttcca tgacatcact ttgccggaat gttttggccc aacgatgcct aatccccagg
    50581 tcagagcgcc cgtcagtaac tggctttcac caaagccaag aatcaaacgc ccgacgacca
    50641 acagggcaaa tttgaacggt gcggagacgg gcaaaatcgc cgccaacagc agcgcgccgc
    50701 cagccagacc acaagctaac atcccctgaa gcgccgaacg ttttgcgcca tattgatcgg
    50761 ccagtcgccc ggcgtaacca cgcgtcagca ccgtagccag aaactgaatg ccgacggcaa
    50821 taccgaccat ggtgttgcca tagcccagtt catgatgaac aaacagcggg ataaccggca
    50881 acggcagccc tacggtcatg taggtgagaa aaaccgcaaa agcgatgcgg aagagcgaaa
    50941 aattggcaga agatcgtgtt tcggtttggc ttacagcagt catgcattac tccagaatgc
    51001 agcgcaaggc gaggaatttc cccgtctcat ctctctggtt tcagggttac ggtgcgttgg
    51061 caggatttaa cgcgtacgtc ttttcagaag gaaatcgaca aagcgggaag tttgcctgga
    51121 acaggcggcg attgtcaata atgtgaaaaa gggaaccatc aggttccctt ttgcgttagt
    51181 gtcggatgcc gcattggcgc gtaatgtcgg atgcgacgct ggcgcgtctt atccgaccta
    51241 ctccgaatta atctttcagc ttgcgcatta ccagcgtggc gttggtgccg ccgaagccga
    51301 agctgttaga cataactgtg gtcagttcgc gatcggtcgt ttcggtcacg atgttcagac
    51361 ccgcagcctg ctcgtccagc tcttcaatgt tgatgctcgg ggcgataaaa ccgtgttcca
    51421 gcatcagcag agagtagata gcttcctgta cgccagcagc gcccagagag tgaccggtca
    51481 ttgctttggt tgcagaaatc gccgggctct tatcgccgaa cacttcacgg atagctgcca
    51541 gttctttcac gtcgccaacc ggagtcgaag taccatgaga gttcaggtag tcgattgggg
    51601 tatcaacacc gtgcatcgcc atcttcatgc agcgcactgc accttcgcca gacggagcaa
    51661 ccatgtctgc gccatcagag gttgcgccgt agccaacgat ttcagcatag atgtgagcac
    51721 cacgcgccag cgcgtgttcc agctcttcaa ccactaccat accgccaccg ccagcgataa
    51781 cgaaaccgtc acggtgagcg tcgtaagtac gggaggcttt ttccggggtg tcgttgtatt
    51841 tagtagacag cgcacccatc gcgtcgaatt cgcaagccat ttcccagcac agctcttcgc
    51901 cgccgccagc aaacacgatg tcctgtttgc ccagttggat ctgctctact gcgttaccga
    51961 tacagtgtgc ggaagtcgca cacgcggagc tgatggagta gttaacgccg tgaattttaa
    52021 acggcgtggc gaggcaggca gaaacgccgg atgccatcgc tttggtgacc acatacgggc
    52081 caaccgcttt caggccgcgc gggccgcgca ttgcgtcagc gccgaaaacc tggaaacgcg
    52141 gggagccgcc gccggaacct gcaatcaggc caacgcgcgg gttattctgg taagcttccg
    52201 gggagaggcc agcatcagca attgcctgct ccatagaaag gaatgcataa atggatgcgt
    52261 cgctcataaa gcgcacaact ttgcggtcaa tgaggccagt ggtatccagt tttacgttgc
    52321 cccagacgtg gctacgcatg ccggaatcct tcagctcctg agagaaagtg atccctgaac
    52381 gtccttcacg cagagatgcc aggacttcct gctggttatt accgatgctg gaaacaatgc
    52441 ccaggccagt aatcactgca cgtttcattc aatacctctg taagtcgcac atagagtaag
    52501 tttcgaatgc acaatagcgt acacttgtac gccgaacaag tccgatcagc caattaatag
    52561 agaaatttgc gcagcctgac acacatcgct aagatcgagc caccgcctgt aagacgagta
    52621 acttacgtga aacactactc catacaacct gccaacctcg aatttaatgc tgagggtaca
    52681 cctgtttccc gagattttga cgatgtctat ttttccaacg ataacggact ggaagagacg
    52741 cgttatgttt ttctcggggg taaccattta gaggcacgtt ttcctgaaca tccacatcct
    52801 ctgtttgtgg tagcagagag cggcttcggc accggattaa acttcctgac gctatggcag
    52861 gcatttgatc agtttcgcga agcatatccg caagcgcaat tacaacgctt acatttcatt
    52921 agttttgaga aatttcccct cgcccgtgcg gatttagcgc tggcgcatca acactggccg
    52981 gagctggccc cgtgggcgga acagcttcag gcgcaatggc ctttgccctt gcccggttgc
    53041 catcgtttat tgctcgatga aggccgcata acgctggatt tatggtttgg cgatataaac
    53101 gaactgacca gccaactgga cgattcgcta aatcaaaaag tagatgcctg gtttctggac
    53161 ggctttgcgc cagcgaaaaa cccggatatg tggacgcaaa atctgtttaa cgccatggcc
    53221 cggctggcgc gtccgggcgg cacgctggcg acctttacgt ctgccggttt tgtccgccgc
    53281 ggtttgcagg aagccggatt cactatgcaa aaacgtaagg gctttgggcg caaacgggaa
    53341 atgctttgtg gggtgatgga actgacatta cccctcccct gctccacgcc gtggtttaac
    53401 cgtacgggca gcagcaaacg ggaagcggcg attatcggcg gtggtattgc cagcgcgttg
    53461 ttgtcgctgg cgctattgcg tcgcggctgg caggtaacac tttattgcgc ggatgaggcc
    53521 cccgcactgg gtgcttccgg caatcgccag ggggcgctgt atccgctttt aagtaaacac
    53581 gatgaagcgc taaaccgttt tttctctaat gcgtttactt ttgctcgtcg gttttacgat
    53641 ttattgcccg ttaaatttga tcatgactgg tgcggcgtca cgcagttagg ctgggatgag
    53701 aaaagccagc ataaaatcgc acagatgttg tcgatggatt tacccacaga actggctgta
    53761 gccgttgagg caaatgcggt tgaacaaatt acgggcgttg cgacaaattg cagcggtatt
    53821 acttatccgc aaggtggctg gctgtgtcca gcagaactga cccgtaatgt gctggaactg
    53881 gcgcaacagc agggtttgca gattcattat caatatcagt tacaggattt atcccgtaag
    53941 gatgacggtt ggttgttgaa ttttgcagga gatcagcaag caacacacag tttagtggta
    54001 ctggcgaacg ggcatcaaat cagccgtttc agccaaacgt catctctgcc agtatattcg
    54061 gtggccggtc aagtcagcca tattccgaca acgccggagc tggcgaaact gaagcaagtg
    54121 ctgtgctatg acggttatct cacgccgcaa aatccggcga atcagcacca ttgtattggt
    54181 gccagttatc atcgcggcag cgaagagacg gcgtacagtg atgaagatca gcagcagaat
    54241 cgccagcggt tgattgattg tttcccgcag gtacagtggg caaaagaggt tgatgtcagt
    54301 ggtaaagagg cgcgctgcgg tgtgcgttgt gctactcgcg atcatctgcc aatggtaggc
    54361 aacgtgcctg attatgacgc tacactcgtg gaatatgcgt cgctggcgga gaagaaagat
    54421 gaagcggtaa gcgcgccggt ttatgacgat ctctttatgt ttgctgcttt aggttcgcgc
    54481 ggtttgtgtt ctgccccgct gtgtgccgag attctggcgg cacagatgag tgaagaaccg
    54541 attccgatgg atgccagcac gctggcggcg ttaaacccga atcggttatg ggtgcggaag
    54601 ttgttgaagg gtaaagcggt taaggcgggg taatctgctc tggcattgtt tgtcggatgc
    54661 ggcgtaaacg ccttatccga cctacgcgtt acctgtaggc ctgataagac gcgataagcg
    54721 tcgcatcagg catggtgctc cagacgtcac aacttactgc tgtgaggcct gctgaaacag
    54781 gtgttcccac atatcggtca ccagcgcctg gtcacgcggc gacaattcac cggcaccaat
    54841 ggctttttcc agactctggc taacggttgt atgtaccgcc tgagcggagt ggtcgtcacc
    54901 actttccagt tctgcgatgg ctaatgtcag gtggccacgc aaatacccac tggcaaacaa
    54961 ctcatcatca ctggcatggt caaccatacc gtcgattaat gccagaatgc gtgattcaaa
    55021 ctccgcgatc atcttctttc ctcattgtaa aacgtggcgc tggcttcagt tgagcgcttc
    55081 cggccacggg aactgttccg ccgtaagttc cggcgtgtga taataatttt gtagtgcttt
    55141 aatgaagcgt gccggacgtt cgggaatgcc gtttgccaga taatccatca cctgcgcatg
    55201 tacccgccgt tgaaacacca cgcggtccgg ttcgaaatcc ccttccagat tgtcgcagct
    55261 aacattaaac ggatatcccg ctgccacgca gaacaaccag tccagcgcct gcggcttcac
    55321 ttcaacatct tcaaactggc tttgtgtctg ggcatcgcgt ccgtccgggc aataccagta
    55381 gccgaaatca accagctcac ggcgcgcttt cccggcaata caccagtgcg aaatctcgtg
    55441 gatggcgctg gcataaaagc catgagcgaa gacgattctg ttatacggta cttccgcatc
    55501 agcaggaaga tagatcggtt cgtcgtcgcc tttaatcaga cgggtattaa attcatcggc
    55561 aaagcagcta ttaaaaatct caatcaactg ctcatagtgg tgtgtactgt tcattagttc
    55621 atccccaacc agtggaggat ctcctgtcca tggctatcgt aaagtaattt ggcactcatc
    55681 accgccgaga cgataacgat catcgggcgg atcagctttt gtcctttgct caacaccagt
    55741 cttgaaccca tgcgcgcgcc gaggaactgc cccaccagca tcacaaagcc cgtcgcccaa
    55801 atcactttgc cgccgagaat aaacagcagc agaccgccaa tgtttgacgt tgcgttaagt
    55861 aatttggcgt gagcagtggc tttggcgagg ttgaatccgc acagcgtaac gaaggccagc
    55921 gcgtaaaacg atccggcagc cgggccaaaa aatccatcgt aaaaaccgac gcagcccccc
    55981 gccaccagcg caaatggcag tccatacatc cgacgctggc gatcttcttc acccagcttt
    56041 ggcatcagca agaaatagag gccgatacaa atcaccagaa taggcaaaat ctgccgtaag
    56101 acatcggcct gaacatactg caccagtagc gcgccgctca ttgagccgac aaaggtcatg
    56161 gcgatattga gtttttgatc gcttaaacta accactttac ggcgaataaa gtagatagtg
    56221 gcggaaatag agccaccgca ggcttgcagt ttattggttg ccagcgcgtt agcgggagac
    56281 atccccgccg ccatcaatgc cggaatggtg agtaacccac cgccaccggc aatcgagtcg
    56341 ataaatcccg ccagcatggc gacaaaaaag agaactccca gcagcagcgg ggaaaccata
    56401 aacaggctat taaacgtttc cattagatca cgtgctcatc cagtagcgcc tggcaggaag
    56461 gcggcaacgg aggcggtgtc ttcttctcag gctttgttgt tcccggtttt ggaggttcaa
    56521 accagctttg cagttctgcc ccgcaaccat cgcctggtgg cggtaaaggt tgatcctcac
    56581 actccagact atcggcagga caacgtaatc gtacatgcat atgcgcgcga tgctggaacc
    56641 agggtcgcac tttgcgcaac cagtcgcgat cggtgcccgc atcaaggcaa agttgttgct
    56701 taatcgccgg attaacaaaa atgcgcgtga cgtctttatc ctgggcggcg agtttgatca
    56761 agctgaaaat ttctggcttc cacagcgtcg ggacaacgtg tttaccgtcg cgggaaacta
    56821 aatctaacgc ttgcgggcgc aagagttgcg cggaggtcca gcgtgttttc ggcagttgca
    56881 ggaagatatc gacatccagt ccggtctggt ggctggcgtg accgccgttg aaacgaccac
    56941 cagcaggcat ccccatatcg ccaatcagca ccgtacccat gcccagattg ctcacctggc
    57001 gactcagacg ctggataaac atcaccaggt ctgggtgacc gaaatagcga cgctgatcgg
    57061 tacgcatgac ctgataatgt tcggactgta tcggcaacgt gtcagcaccg atgatacagc
    57121 cattagaaaa actgcctatc gattgtgcgc tacccggcac aggttgggtt attttttgcc
    57181 acggcgtcgc tgccaggctg gcgctactgg caagcagagc cagcagcgca atcgcggttt
    57241 tgttcatttt ttaccagcgt ggaatttcag tcttcacatc ggcattttgc gcccgctgcc
    57301 gtaacaggtg atccatcaaa acgatcgcca gcatcgcttc tgcgatcggc accgcgcgga
    57361 tcccaacaca aggatcgtga cggcctttgg tgatcatctc aacttcttcg ccaaagcggt
    57421 taatagtgcg ccccggcacg gtaatgctgg aggtcggttt cagcgccatg tgggcaatga
    57481 tttgctgccc gctgctgata ccaccaagaa tgccgcccgc atggttgctc tggaaaccgt
    57541 ctttggtgat ttcgtcgcgg ttctggctgc cacgcagcgc taccacgtca aaaccatcac
    57601 caatttccac gcctttcacc gcgttaatgc tcattagcgc atgggcgatg tcggcatcca
    57661 ggcggtcaaa gaccggctcg ccaagtccgg cgggtacgcc actggcaacg acggtgactt
    57721 tcgcaccaat agagtcgcct tcttttttca gcgcgcgcat cagttcatct aacgcgtcga
    57781 ttttgtccgg gtccgggcag aagaatggat tttgctcgac ctgagaccag tctttgattt
    57841 ccagcggaat gtcgcccatc tgggtcaggc aaccgcgaat ctcaatgcca aatttctcgg
    57901 cgagatattt tttggcaatc gcccctgctg caacgcgcat agcggtttca cgggcggaag
    57961 aacgtccacc gccgcgataa tcacgcaggc cgtatttttg ttcgtaagtg taatcggcat
    58021 gacctggacg gaaaacgtcc ttaatcgcac tataatcctg agaacgctgg tcggtatttt
    58081 cgatcaacaa tccgatgctg gtgccagtag taacaccttc aaaaacaccg gagagaattt
    58141 tgacctgatc cggctcgcgg cgctgggtgg tatagcgcga tgtcccaggg cgacgacgat
    58201 caaggtcatg ttgcaggtcc gcttccgtca gcggaatgcc tggcggaaca ccatcgacga
    58261 tgcagccgag cgccagcccg tgcgattcgc cgaaggtggt tacgcgaaag agttgtccaa
    58321 ttgtgtttcc agccatcacg gctccgttat tgttgtgttt gcgtgtttac ttaatcttta
    58381 taaatcgcga aatgttctcg tgcggcaata agctgctctt tagtgagcat aaacacacca
    58441 tcgccgccgt tatcaaactc cagccaggtg aacggaacat ccggatattg ttccataaga
    58501 tgtaccatgc tgttgccgac ttcacaaatc agcacgccat catcagcgag gtaatctgcc
    58561 gcgtttccga gaatgcgacg cgtcagtttc aggccgtcgg tgccagatgc caggcccagt
    58621 tccggctcgt ggcgatattc gtttggcagg tcggacatat cttccgcatc gacatacggc
    58681 gggttagtga caatcaggtc gtactgcact ttcggcaagt cgcggaacaa atcggaccga
    58741 ataggaatga cgttgtggat cagaccgtgt tcttcgatgt tctgttcagc aaccgccagc
    58801 gcgtcgggag agatgtccac cgcgtcgact tccgcttccg ggaaggcata agcacaggca
    58861 atggcgatgc agccgctacc ggtacacata tctaaaatgt gctgcggttg cttgctgatg
    58921 agtccggcaa atttattgtt gatcagttca ccaatcggcg agcgcggcac cagcacgcgt
    58981 tcatcgacgt aaaattcatg gccgcagaac caggctctgt tggtcaggta agccaccgga
    59041 atgcgttcgt tgacgcggcg gatcacgcgc tcaacaatac ggtgtttttc gctggaggtc
    59101 agacgcgcgg tgcgcatgtc ttccggaata tccagcggca ggtagagtga aggcaacacc
    59161 agttgcacgg cttcatccca cgggttatcg gtgccgtggc cgtaccagat attcgccgcg
    59221 ctgaagcggc tcaccgacca gcgcaacatg tcctgaatgg tttgcagctc atttactgct
    59281 tcatcaacga aaattttatc cacgtattcc tccagggcat gatcgcaata atttcggcgg
    59341 ctagtttgcc atgaagatga cgataaatca gcattcacgc gcggtgagtg aggaaaaata
    59401 cgtttaaaac gatcgattgc gctacgagtc gggtaaactg taggaaaatt agaaatagag
    59461 aaagataaat gaaaaagaaa acaacactta gcgaggagga ccaggcgctg tttcgccagt
    59521 tgatggcggg tactcgcaag attaagcagg acacgattgt ccaccgaccg cagcgtaaaa
    59581 aaatcagcga agtaccagta aagcggttga ttcaggagca ggccgatgcc agccactatt
    59641 tttcggacga gtttcaacca ttattaaata ctgaaggtcc ggtgaaatat gttcgcccgg
    59701 atgtcagcca ttttgaggcg aagaagttac gccgtggcga ttattcaccg gagttgtttc
    59761 ttgatttgca cggtctgacg cagctacaag ccaaacagga actgggggcg ttgattgccg
    59821 cctgccgccg tgaacatgtg ttttgtgcct gcgtgatgca tgggcacggg aagcatattt
    59881 tgaagcagca aacgccgctg tggctggcgc aacatccaca tgtgatggca tttcaccagg
    59941 caccaaaaga gtatggtggt gatgcggctt tgttggtgtt gattgaagtg gaagagtggc
    60001 tgccgccgga attgccctaa taaatattgc ggtataaacg tcttctccga ccaggatact
    60061 gaccggagaa gaattaaccc tacaactcat tcaaaatgta ctggaaacga caggtggcat
    60121 cgattggctg ctgactgctg gtgtcgatcc gtatttgcat atcatgcagt tgcttatcgg
    60181 taattggatg tgctaccggc gttactgtga ctttgctgtc gtcacacccc gacgtgctga
    60241 atgtgatcat atacgacata aagcgacaat aagcgccacg atcgtccatt cggcttccat
    60301 cacacacccg cccgtcgcgc atcaggtaag tcgagagcgt ttgtgttatg actccccccg
    60361 tcgattgcag cgttagcatc ttgttatgga ggacgtagtt ctcattccag gagatatcat
    60421 aggggccaac cggctccgtt gggcaccggg tttgttttgc tgatggacca atgtaagtat
    60481 aacctctcgc agcagtactc accgtgttgg tactgaccaa ccacgggcac ccgtgagttt
    60541 caccatgcac gatgatatcg acccccagat caacacatga ccatccatcc gtaatccctg
    60601 ggcaattgga gttatccaca gtattactct gatgagtgat gttcatcgtt ggtgctgatc
    60661 ccggtcccgt ccaaaccgtg ttagggatat tccccaacca caacgtatat ccatcctgtg
    60721 catattcgcc ataatagacc ccttccggcg tcaagacatc gatacgaaag acaacttttg
    60781 ttgtagcccc gttaccccaa aatccggtat aagtcttcac atccctgaat gtgacgtccg
    60841 cccaggcggt tgcactcagt agcccggtca gcagtaaaaa aaacagtccg ctcatttttt
    60901 tcatgttaaa tatactcaaa cgtcgcagtg agggaggccg taaagtcacc catcgtcaca
    60961 tcccgcccgc tttttgcctg tagccaggca ttaaaatgca gatcattgtt gccgctgctc
    61021 agcacaaatg tcgccccgct ggtattgttg attagcacag cagtgccgtc ggtcttttcc
    61081 atgccaatcc ccacaccttg tgctgtcgaa gcggcatcca gcgccagaaa accgggctgc
    61141 tcgctgtctt ccgttccggt aagtgtcacc cgaacctcat actgagcagg ccctttgcaa
    61201 tctttaagct gaaacaccac cggtacgcgc gcagattgcc cggtcaccat cagatctcta
    61261 cggctgaccg tggggaaatg cacttccgcc agcacctcgc cctgaaccac cagcgtgcag
    61321 gacttactga gtaaattgcc gtagaaatgc aggttgtctg ccgcctgaac attcggcgtc
    61381 agcagcaccg cggccagcgc agccgcgcag tgaaatatcc gttttaggct cattggtaat
    61441 ccacctgtaa tgttgcccag gcagaaaagg ttccttcgct gagtgaagca tcactggctt
    61501 tcaccggtac agcttgcagc gttggcggcg ttgacaggtt gattttcagc ggcgtaccca
    61561 acgtgaacgg ctggccattt tgttgcagct caatccccag cccggtgacg tttgtctcaa
    61621 tagccgcgtt atcgtagctg gtctggctgc ccgtccagct cagcgtcatc tcccaggcat
    61681 cgtcgcgcac gtcgggatcg catgtaatgg tatagggcac attctggcgg aagttattgc
    61741 cgttgatgtt gtcgataatg acgtcacgaa actcaacttc aacggttttc ccgtcactga
    61801 tggcacaggc gggcggcgaa accaatgtgc catgaaatgt gatatcgcta tcggccgcct
    61861 gtgcaatacc gcaataacaa ccgaataagc agagcgcaaa tcgtttcatt gatactccac
    61921 caccattgtc atggttgcgc taaactctga tgccgtaagc tgtgtgccgc tttgtttcac
    61981 cggcacggct tcgaaacccg ggcgcgaatt aacgttaaac ggcagccagt tattacccgc
    62041 caacgcaacc ggcgcatggc tggacgcatc ctgtatgcga atgccaaaac cattgatgcc
    62101 cgtactgagg accgtttcac cgttaatggt ggtggtggtc ccctgtaact gcatctgtag
    62161 gtcatcgctg acgctgttcg aacagttcag ggtgtaacca acaggctgcc gatagttgct
    62221 gccgtcgatg tttttaataa tgacattgcc aaactccacc gcgctgcctt ttaccgtaca
    62281 gggcggcggt gcatccacca gtatacgaag cgttaagttg accgttttac tatcggccca
    62341 ggcggagccg caggccagta acaccatgcc agcgacgggt aataaaactc ctttcatgct
    62401 ggatctcctg tcattagcct tttaggcttt gagcttcatc caccttgcag gtgtctcctt
    62461 cacaacggaa gaccagcggt aaacgtgcgc cgtagtcgtt gatgtaggtc agcaccggag
    62521 cgctgttcat ttttgccttt aacggttgtg acgttttcgg cggcatcacc agtggtttaa
    62581 agcccgcagc agttagcccc tttttctgcg tactggcatc gctgatgatg acgtggtacg
    62641 gcgtcgggtt attgacgata tagtcctggc cgctgcgcgt gagtgtgacc ttaaactgcc
    62701 acggttttct catgtcaatc ttctccagcg cctttggtcg ccagaacagc ttgatgcggg
    62761 tttgcagcgc aatttgcagg gtgttggctt tcccggactt tggcgggatc tcacgcacat
    62821 tgtagtagaa caggctttca cggtcagacg gcagcgtgtg aatgtccggc agcgcctgaa
    62881 tcttcacctg accgttcatc atggcgtcaa tacgctgcac cggcggcagt accgccagcg
    62941 gcgaagtgat tttgttgccc ttctcgtctt ccagccagct ttgcgccaga taaggcagct
    63001 tttcgttatt gttgcgcagg gttacgctta tcgatttatc actttcgtta aacaccagac
    63061 gggtgcgatc cggagtgact gatgcgtgcg ccgccaggtt ggtggtggtc aacagtaccg
    63121 ccagcgtcgt gctgaccacc attgaacagg ataatttata aaacattgat tgttccttaa
    63181 tcatattatt gagtggctga aattgacgtc ggcgcttcag atggcgtgac ctgccgagtc
    63241 tggtcctgaa taacgggctt aatttccggc gctaaagaat cgggggctgt cgttcccttt
    63301 tgttcacacg gcaacaacag gccgcggaac agatcggcag gtagcggctt cggcaatacg
    63361 atctcgcatt gtgcgctgcc ttcccagaac accatcatat gctcacccgc attgatcccc
    63421 gccagataga cattgccttc atcatccaca atgccaacct gctgctgctc gtcgtttttt
    63481 acttccgcgc caaacggcgg gtagctaccg tcacgcaacc gcagtaccgc catcgctttt
    63541 tgcccgctga tcactttgaa tttacgatag ccgattgcgc cttccgtcag agtcgcctgc
    63601 accaccgact gggtggcttc cgcatcttcc ggcaagttgt ttaaatctat atacgcctga
    63661 ttgcgatagt agttgttaat atcggcgacc accgccttgc caaacatatt ggtgtacacc
    63721 ggcgcgccgt tgctttcgac cggcacgttg gcaataccgt cggcgtcaat cagcaggcgt
    63781 gtgccgccca tgttttgagt gcgatgcagc gccccaccgt gcgcggtcag cgttgccccg
    63841 ccctgtaagg cgatccccgc cgaacggtat tctccttcat ggtagttggc gctgagatct
    63901 accttcgcca acgtgccgtc gtggctcaga taaccatcca cgctaccgtg ctgttcgctg
    63961 gtgccgacgt taatctggta gtgcgttgcg tcatcgatgc gattaaagta gccgacctga
    64021 ctgctgtccg acccgctacc gtaagagccg ttgtaggtca cggtgctgct gtcgctccac
    64081 ggaatgctca tgctgaggta cattccctta tccgtattat cgtcatattc gtagcgatag
    64141 ccggtcaccg agatgctcat attgcgaatg ctccccatat taaaatagtg ggaaaacatc
    64201 aggttatagt ttgtctgttc cgggcgatcc cagtaagtac gatgggagta gttgagatag
    64261 accgagacac ccgctgcggc aaagttctgg ttatacgtga tcgtatacat ctctttgtcg
    64321 tttccggtcc gcgccatgtc cgactggctc gcgtccagat actcgctcat agtcataaag
    64381 ttcttttcgg agaaacggta gcctgcaaag gtgacgcggc tgttaagttc gtcaaagtct
    64441 ttggcatagc tcacgcgaaa ggagttgccg tccagttttc ctttgccgta tgcgctgtca
    64501 tgatccaggt tgacgtgcga gtgagtcaca tcgaacgcca gcgcgccaaa ctgtgcgagg
    64561 tcgcgcccca cccccatcgc cgccgactgg tagtgctcat ctgccagcgc gccaccgtaa
    64621 agcgaccagc catctgccac cccccatgat gcttctccgc cggaaaaaaa tccgccttcg
    64681 gtcttgtggt tccagtcttc cggacgcccc atcatcactt tgtaacgcac ctgcccctga
    64741 cgagtgagga atggcatgga tgcggtggtg acgtcatatt cctgcacctg accattctgt
    64801 tcttcaacac ggacgtgtag tgtgccagag acagaatcgc cgatatcctg aatgcggaat
    64861 ggcccggcgg gaacctgggt ttcgtaaagt acccggccca tctggctgat ggtcactttt
    64921 gcgctgctgt gcgccacgcc agaaacatct ggcgcatagc cgcgcagatt gggcggcagc
    64981 atctggtcat cggtgctgac actgctgccg atatagttaa agccgtcgaa aatatcggaa
    65041 ttgagataat cttctcccag cgacagcttc gcttttaaag agggtaaagc tcgccaggcg
    65101 taataacggc tccagtccca gtttttactc gttgtactgt tactgctgtc atcttcatcg
    65161 tcgttgctgc gggtgtgctg ataatcactt tgccagtctg cacggaaacg ccatgcccca
    65221 aggtttgccc caactgtacc gttaccgctg atatcatgtg agtcctcgcc cccttgctcc
    65281 tgatggcgag tttgcgcatt gaggctgtag tcggcaatca gcccagaaat accatcgtcc
    65341 cagcgtgagg gagggtccca gtcgctgctg gtatattcga ggtaagcctg tggcactgtc
    65401 agcagcaaag ccgactggct taaatcattc tcgacttcca tcccgtctaa ttgccccggt
    65461 ttaaggcatt catcgttgtg cgtccactgc aggctttttg ctatcccttc tttcagcccc
    65521 agcgccgcca ctaactcagg tgtcaggcag gcataagttt ttgttggatc gttttcagag
    65581 acataccaat taatgtcgta ttcatcagaa agggattgtt tatttataaa tacacgtaaa
    65641 ttatatttac ccgcgtcgac ataccctttt tttgaaaact taccgagatc aattttcgtg
    65701 tcgcccttta actcaaggaa acgggggtca aattgaatgg aatcatcagc ccatgcattg
    65761 actgatccac cagagattgc cagcgcaata tagcaggcga ttccccgcag ccgaaaattt
    65821 gagtgattag gcatacacat atccgtttgt gaaacagtcg taaatccgtt gtgcgttgaa
    65881 taaccccaca gcagaacgct gtggggttgt cacatcagag ataggtaatc tggaatgtgg
    65941 tcagggtttc gaactggccg agatccggcg catcggtttc acccaccagc caggctttaa
    66001 agttcagcgt ttgcttgtct ttacccttgc tagttgaagc atccatcacg attggctgaa
    66061 caatcttttc gcccacttta taacctttgc catgggtatc gccgattacc aggctcacgt
    66121 ggttcatggc aacaccgctg tcaacattga ataacgcata gttatctgcg ttggctggcc
    66181 ccgcgtagtt agtgccggtg aacgtggtct ccatgtttga ttcagtggta aacacgcaat
    66241 cctgtaaatg gatctggaaa tctttcggtg tggtagtgcc gccgccagtc agtttagccg
    66301 caccgatatc gcccatatcg acttccagtt tatgatcgtc tggaacgatg gagcacgggg
    66361 agtcttcaat agtgccgtaa aaacgtgcgg taccgttgtt acctgcggca aaagcagaac
    66421 tggagacgac tgcgcccatg accattgcgg cagcaatggc tgttttggca aacttactca
    66481 ttatttgtcc ttaaatcatt aaaagtcata atataagtac ctgacataaa attaatatat
    66541 gttatgtcca atacttatag ttagccattg aacatataca ttccaatata attatagaat
    66601 gtaaacaagt attctctggt gtgtctttat gttggtctta tctataaaaa aactcaattt
    66661 agtaatactt aaagacttta tgtagatttt attaattaat acatcggcaa aatactttca
    66721 ccactttcca acaaaaaaac atgcgaatta tcaacaaaaa acaaactatc ataatcaaca
    66781 aaaatgaatt gcttataaag cacactaaaa aattataatg accttacc
//
LOCUS       DAFGPF010000010        65742 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFGPF010000010 DAFGPF010000000
VERSION     DAFGPF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 65742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65742
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.010"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            108..1805
                     /gene="ypdA"
                     /locus_tag="LSX49_000809"
     CDS             108..1805
                     /gene="ypdA"
                     /locus_tag="LSX49_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     YpdA"
                     /protein_id="HBL7167258.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAMTNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            1820..2554
                     /gene="ypdB"
                     /locus_tag="LSX49_000810"
     CDS             1820..2554
                     /gene="ypdB"
                     /locus_tag="LSX49_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator YpdB"
                     /protein_id="HBL7167259.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSCSKVKEFRQLMHL"
     gene            2567..3424
                     /locus_tag="LSX49_000811"
     CDS             2567..3424
                     /locus_tag="LSX49_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7167260.1"
                     /translation="MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPTSLPVGSL
                     CIDFPRLDIVLRGEYGNLLEAKQQRMVEGEMLFIPARAANLPVNNKPVLLLSLVFAPT
                     WLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
                     LHLCRNVVNMPPGNSQPRGDFLYHSICNWIQDNYAQLLTRESVAQFFNITPNHLSKLF
                     AQHGTMRFIEYVRWVRMAKARMILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTP
                     GEYSARFQG"
     gene            complement(3427..5922)
                     /gene="ptsP"
                     /locus_tag="LSX49_000812"
     CDS             complement(3427..5922)
                     /gene="ptsP"
                     /locus_tag="LSX49_000812"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL7167261.1"
                     /translation="MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTLAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRVIPASAQDSTLLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRHLMAEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKLTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTAAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFAPEED
                     VRPLLALENIFVDQSFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLVKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(5947..6984)
                     /gene="ypdE"
                     /locus_tag="LSX49_000813"
     CDS             complement(5947..6984)
                     /gene="ypdE"
                     /locus_tag="LSX49_000813"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL7167262.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILREEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQSVRITTR
                     EECKIPGLLDSDRQGNDVSAMRVDIGARSCDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQSD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMEQLLSALIQRLT
                     RETVVQLTDFR"
     gene            complement(6984..8069)
                     /gene="ypdF"
                     /locus_tag="LSX49_000814"
     CDS             complement(6984..8069)
                     /gene="ypdF"
                     /locus_tag="LSX49_000814"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL7167263.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISR
                     ESAHILVDSRYYADVEARTQGYQLHLLDAMHTLATIVRQIIADEQLQTLGFEGQQVSW
                     ETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSE
                     CEIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFNVYQIVLQAQLAAISVIRPGVRCQQVDDAARRV
                     ITEAGYGKFFGHNTGHAIGIEVHEEPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAVPKTVLLTGEA"
     gene            complement(8084..9331)
                     /locus_tag="LSX49_000815"
     CDS             complement(8084..9331)
                     /locus_tag="LSX49_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBL7167264.1"
                     /translation="MAIKKRSATVVHGASGAAAAVKNPQASKSSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPADIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            complement(9353..9679)
                     /locus_tag="LSX49_000816"
     CDS             complement(9353..9679)
                     /locus_tag="LSX49_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-like phosphotransferase enzyme IIB
                     component 1"
                     /protein_id="HBL7167265.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAAGIIKEIEEM
                     IASEQQ"
     gene            complement(9898..10863)
                     /gene="glk"
                     /locus_tag="LSX49_000817"
     CDS             complement(9898..10863)
                     /gene="glk"
                     /locus_tag="LSX49_000817"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HBL7167266.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEGIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            11067..12323
                     /locus_tag="LSX49_000818"
     CDS             11067..12323
                     /locus_tag="LSX49_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HBL7167267.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQR
                     LPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSNEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVFVLGIGGFILGILGVIGG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            12438..12764
                     /locus_tag="LSX49_000819"
     CDS             12438..12764
                     /locus_tag="LSX49_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HBL7167268.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
     gene            complement(12905..14143)
                     /locus_tag="LSX49_000820"
     CDS             complement(12905..14143)
                     /locus_tag="LSX49_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL7167269.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWV
                     IVVLVVALNIWLLVGTALGL"
     gene            14479..15681
                     /gene="nupC"
                     /locus_tag="LSX49_000821"
     CDS             14479..15681
                     /gene="nupC"
                     /locus_tag="LSX49_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HBL7167270.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            complement(15731..17920)
                     /locus_tag="LSX49_000822"
     CDS             complement(15731..17920)
                     /locus_tag="LSX49_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HBL7167271.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVVLIQLSRLISPLAVIHSNYIFL
                     AWMPLCVMLSILFIFGWRGVVPILCGMFCTNLWNLHLTFLQTAVMIGSQAFAVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVAPIGIKCSMYLVGNFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLSKEKRAFTLS
                     WLAALSVLLLLMCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVLTEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSIYRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGHFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYYISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD"
     gene            complement(18127..18202)
                     /locus_tag="LSX49_000823"
     tRNA            complement(18127..18202)
                     /locus_tag="LSX49_000823"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18167..18169),aa:Ala,seq:ggc)
     gene            complement(18242..18317)
                     /locus_tag="LSX49_000824"
     tRNA            complement(18242..18317)
                     /locus_tag="LSX49_000824"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18282..18284),aa:Ala,seq:ggc)
     gene            18538..18897
                     /locus_tag="LSX49_000825"
     CDS             18538..18897
                     /locus_tag="LSX49_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HBL7167272.1"
                     /translation="MFKERMTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKA
                     RLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLL
                     REGIIGLLQRLGIRDSK"
     gene            18899..19291
                     /locus_tag="LSX49_000826"
     CDS             18899..19291
                     /locus_tag="LSX49_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416898.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HBL7167273.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLLEAEEPLAEYAPGIRTPAYRQIISAIDNMTH
                     SEQEKVAQFLSREGIRNFLARLDIDESA"
     gene            complement(19342..20757)
                     /gene="gltX"
                     /locus_tag="LSX49_000827"
     CDS             complement(19342..20757)
                     /gene="gltX"
                     /locus_tag="LSX49_000827"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBL7167274.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLTAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALAFIAERENQQ"
     gene            21016..21091
                     /locus_tag="LSX49_000828"
     tRNA            21016..21091
                     /locus_tag="LSX49_000828"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21049..21051,aa:Val,seq:tac)
     gene            21136..21211
                     /locus_tag="LSX49_000829"
     tRNA            21136..21211
                     /locus_tag="LSX49_000829"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21169..21171,aa:Val,seq:tac)
     gene            21258..21333
                     /locus_tag="LSX49_000830"
     tRNA            21258..21333
                     /locus_tag="LSX49_000830"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21291..21293,aa:Val,seq:tac)
     gene            21338..21413
                     /locus_tag="LSX49_000831"
     tRNA            21338..21413
                     /locus_tag="LSX49_000831"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21371..21373,aa:Lys,seq:ttt)
     gene            complement(21524..22408)
                     /gene="xapR"
                     /locus_tag="LSX49_000832"
     CDS             complement(21524..22408)
                     /gene="xapR"
                     /locus_tag="LSX49_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XapR"
                     /protein_id="HBL7167275.1"
                     /translation="MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKE
                     LENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARVEQIGRGEAGRIELG
                     VVGTAMWGRMRPVMRRFLRENPNVEVLFREKMPAMQMALLERRELDAGIWRMATEPPT
                     GFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQV
                     GFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKERIPADLYIVY
                     ETQQVTPALVKLLAALAQ"
     gene            complement(22449..22607)
                     /locus_tag="LSX49_000833"
     CDS             complement(22449..22607)
                     /locus_tag="LSX49_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1427 family protein"
                     /protein_id="HBL7167276.1"
                     /translation="MKDILFSSGVGFGIGALFTIVRLPIPVPNVLPGILSIVFMYVGY
                     LVVKYFMP"
     gene            complement(22660..23916)
                     /gene="xapB"
                     /locus_tag="LSX49_000834"
     CDS             complement(22660..23916)
                     /gene="xapB"
                     /locus_tag="LSX49_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine/proton symporter XapB"
                     /protein_id="HBL7167277.1"
                     /translation="MSIALRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVY
                     SSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVN
                     AMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSL
                     QLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMVAWTLRFGFFAYGDPSPTGFILLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWHTIWLMFAGYAL
                     FLAVIFFFGFKYNHDPEKITHRSVTH"
     gene            complement(23977..24810)
                     /gene="xapA"
                     /locus_tag="LSX49_000835"
     CDS             complement(23977..24810)
                     /gene="xapA"
                     /locus_tag="LSX49_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HBL7167278.1"
                     /translation="MYQAQFSHNPLYCVDIIKTYKPDFTPRVAFILGSGLGALADQIE
                     NAVAISYEKLPGFPVSTVHGHAGELVLGYLQGVPVVCMKGRGHFYEGRGMTIMTDAIR
                     TFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDERFGERFFSL
                     ANAYDAEYRALLQKVAKEEGVPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCELKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI
                     A"
     gene            25059..25823
                     /locus_tag="LSX49_000836"
     CDS             25059..25823
                     /locus_tag="LSX49_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167279.1"
                     /translation="MKKHLFTLTLSSVLAIPAVSHAEFKGGFADIGIHYLDWTSRTTE
                     KSSTKSHKDDFGYLELEGGANFSWGEMYGFFDWENFYNDRHDKPGSEQRYTFKNTNRI
                     YLGDTGFNLYLHAYGTYGSANRVNFHDDMFLYGIGYNFTGSGWWFKPFFAKRYTDQTY
                     YTGDNGYVAGWVAGYSFMLGSEKFTLTNWNEYEFDRDATYAAGNGGKEGLNGAVALWW
                     NATSHITTGIQYRYADDKLGEDFYQDAIIYSIKFNF"
     gene            complement(25862..26788)
                     /locus_tag="LSX49_000837"
     CDS             complement(25862..26788)
                     /locus_tag="LSX49_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7167280.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFVLHDRPQQWVMESIRQGDVDFGIVIDPGPVGDLQCE
                     AILSEPFFLLCHRDSALAVEDYVPWQALQGAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAEALWDVVRDQGNALMAGREGDPLYQI"
     gene            26878..27876
                     /locus_tag="LSX49_000838"
     CDS             26878..27876
                     /locus_tag="LSX49_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HBL7167281.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEQLQAQQESSADKA"
     gene            complement(27873..28091)
                     /locus_tag="LSX49_000839"
     CDS             complement(27873..28091)
                     /locus_tag="LSX49_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HBL7167282.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKIEGLTQLVQPLKRPL"
     gene            complement(28093..30108)
                     /gene="ligA"
                     /locus_tag="LSX49_000840"
     CDS             complement(28093..30108)
                     /gene="ligA"
                     /locus_tag="LSX49_000840"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBL7167283.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLMQFKAWGLPVSDRVTLCESAEEVLAFYHKVEKD
                     RPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPEPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDETEMLRLLGS"
     gene            complement(30179..31177)
                     /gene="zipA"
                     /locus_tag="LSX49_000841"
     CDS             complement(30179..31177)
                     /gene="zipA"
                     /locus_tag="LSX49_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HBL7167284.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEVARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPRPTQPVQQPVQQPAYQPQPEQPLQQPVSPQVASAPQPVHSA
                     PQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLN
                     SIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQV
                     PSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            31407..32168
                     /gene="cysZ"
                     /locus_tag="LSX49_000842"
     CDS             31407..32168
                     /gene="cysZ"
                     /locus_tag="LSX49_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HBL7167285.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            32353..33324
                     /gene="cysK"
                     /locus_tag="LSX49_000843"
     CDS             32353..33324
                     /gene="cysK"
                     /locus_tag="LSX49_000843"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBL7167286.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            33708..33965
                     /gene="ptsH"
                     /locus_tag="LSX49_000844"
     CDS             33708..33965
                     /gene="ptsH"
                     /locus_tag="LSX49_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HBL7167287.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            34010..35737
                     /gene="ptsI"
                     /locus_tag="LSX49_000845"
     CDS             34010..35737
                     /gene="ptsI"
                     /locus_tag="LSX49_000845"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HBL7167288.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIIIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            35778..36287
                     /gene="crr"
                     /locus_tag="LSX49_000846"
     CDS             35778..36287
                     /gene="crr"
                     /locus_tag="LSX49_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL7167289.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(36330..37181)
                     /gene="pdxK"
                     /locus_tag="LSX49_000847"
                     /gene_synonym="thiJ"
     CDS             complement(36330..37181)
                     /gene="pdxK"
                     /locus_tag="LSX49_000847"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HBL7167290.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKDCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGKALTDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            37286..37654
                     /locus_tag="LSX49_000848"
     CDS             37286..37654
                     /locus_tag="LSX49_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HBL7167291.1"
                     /translation="MKKIICLVVTLLMTLPAYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCDEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKMPGKSDE
                     NAQPFLHALIAQTDKTVPAQ"
     gene            complement(37657..38568)
                     /gene="cysM"
                     /locus_tag="LSX49_000849"
     CDS             complement(37657..38568)
                     /gene="cysM"
                     /locus_tag="LSX49_000849"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HBL7167292.1"
                     /translation="MSTLEQTIGNTPLVKLQRMAPDNGSEVWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPAEYLP
                     GIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(38703..39800)
                     /gene="cysA"
                     /locus_tag="LSX49_000850"
     CDS             complement(38703..39800)
                     /gene="cysA"
                     /locus_tag="LSX49_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HBL7167293.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPLTVVMHGDDAPQRGD
                     RLYVGLQHARLYNGDERIETRDEELALAQSA"
     gene            complement(39790..40665)
                     /gene="cysW"
                     /locus_tag="LSX49_000851"
     CDS             complement(39790..40665)
                     /gene="cysW"
                     /locus_tag="LSX49_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HBL7167294.1"
                     /translation="MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            complement(40665..41498)
                     /gene="cysT"
                     /locus_tag="LSX49_000852"
     CDS             complement(40665..41498)
                     /gene="cysT"
                     /locus_tag="LSX49_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HBL7167295.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLAQMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            complement(41498..42514)
                     /gene="cysP"
                     /locus_tag="LSX49_000853"
     CDS             complement(41498..42514)
                     /gene="cysP"
                     /locus_tag="LSX49_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HBL7167296.1"
                     /translation="MAVNLLKKNSLVLVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMGKLKDKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRK"
     gene            complement(42672..43463)
                     /gene="ucpA"
                     /locus_tag="LSX49_000854"
     CDS             complement(42672..43463)
                     /gene="ucpA"
                     /locus_tag="LSX49_000854"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416921.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HBL7167297.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DEDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPM
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            43743..44639
                     /gene="murQ"
                     /locus_tag="LSX49_000855"
     CDS             43743..44639
                     /gene="murQ"
                     /locus_tag="LSX49_000855"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL7167298.1"
                     /translation="MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHTQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSSTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLD
                     AAEAKKCLDQHGGFIRKALEKE"
     gene            44643..46067
                     /gene="murP"
                     /locus_tag="LSX49_000856"
     CDS             44643..46067
                     /gene="murP"
                     /locus_tag="LSX49_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HBL7167299.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KARQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIECMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVSGFIFTTLFGCRNVNLD"
     gene            complement(46245..47144)
                     /gene="yfeX"
                     /locus_tag="LSX49_000857"
     CDS             complement(46245..47144)
                     /gene="yfeX"
                     /locus_tag="LSX49_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HBL7167300.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            complement(47240..47815)
                     /locus_tag="LSX49_000858"
     CDS             complement(47240..47815)
                     /locus_tag="LSX49_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HBL7167301.1"
                     /translation="MKSLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGNNVAMVINGDQG
                     TISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADSDDNRAVECKAEGSQHISY
                     QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            complement(47876..48325)
                     /locus_tag="LSX49_000859"
     CDS             complement(47876..48325)
                     /locus_tag="LSX49_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HBL7167302.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRASFPRIWHVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEEKE"
     gene            complement(48312..48737)
                     /locus_tag="LSX49_000860"
     CDS             complement(48312..48737)
                     /locus_tag="LSX49_000860"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HBL7167303.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLSPWNDPEMDIERKMNHDVSL
                     FLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            48951..49820
                     /gene="amiA"
                     /locus_tag="LSX49_000861"
     CDS             48951..49820
                     /gene="amiA"
                     /locus_tag="LSX49_000861"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HBL7167304.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKEEPLKTSNG
                     HSKPKAKKSGGRRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYF
                     HWFDNQKAHSRKR"
     gene            49824..50723
                     /gene="hemF"
                     /locus_tag="LSX49_000862"
     CDS             49824..50723
                     /gene="hemF"
                     /locus_tag="LSX49_000862"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HBL7167305.1"
                     /translation="MKPDAHLVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVY
                     PRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVE
                     RRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPKDGSPEAALSEFIKVRDWV"
     gene            complement(50729..51781)
                     /gene="eutR"
                     /locus_tag="LSX49_000863"
     CDS             complement(50729..51781)
                     /gene="eutR"
                     /locus_tag="LSX49_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HBL7167306.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGELGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEEAQPMMTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMREWG"
     gene            complement(51827..52327)
                     /gene="eutK"
                     /locus_tag="LSX49_000864"
     CDS             complement(51827..52327)
                     /gene="eutK"
                     /locus_tag="LSX49_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311336.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HBL7167307.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVKEPD
                     APVIVAESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            complement(52340..52999)
                     /gene="eutL"
                     /locus_tag="LSX49_000865"
     CDS             complement(52340..52999)
                     /gene="eutL"
                     /locus_tag="LSX49_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBL7167308.1"
                     /translation="MPALDLIRPSVTAMRVIASVNAEFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVANIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            complement(53009..53896)
                     /gene="eutC"
                     /locus_tag="LSX49_000866"
     CDS             complement(53009..53896)
                     /gene="eutC"
                     /locus_tag="LSX49_000866"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit beta"
                     /protein_id="HBL7167309.1"
                     /translation="MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCAAPVTSESCA
                     LDLGSAEAKAWIGVENPHHADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            complement(53917..55278)
                     /gene="eutB"
                     /locus_tag="LSX49_000867"
     CDS             complement(53917..55278)
                     /gene="eutB"
                     /locus_tag="LSX49_000867"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HBL7167310.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCILAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPS
                     LFF"
     gene            complement(55290..56693)
                     /gene="eutA"
                     /locus_tag="LSX49_000868"
     CDS             complement(55290..56693)
                     /gene="eutA"
                     /locus_tag="LSX49_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBL7167311.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKTLILEQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSRSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGPGTDARSLTGAQL
                     AQVTRRMAELIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDETDLVSAWQQALIQLDLCPKTDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            complement(56690..57916)
                     /gene="eutH"
                     /locus_tag="LSX49_000869"
     CDS             complement(56690..57916)
                     /gene="eutH"
                     /locus_tag="LSX49_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBL7167312.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVLIVAVLVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKEDASAAKTEAEAQS"
     gene            complement(58133..59320)
                     /gene="eutG"
                     /locus_tag="LSX49_000870"
     CDS             complement(58133..59320)
                     /gene="eutG"
                     /locus_tag="LSX49_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HBL7167313.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAVLTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGQSLPKAVGYGHDLVARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQIGRALRTKKSDDRD
                     AINAVSELIAEVGINKRLADVGATTGHYGAWAQAAQEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            complement(59310..60146)
                     /gene="eutJ"
                     /locus_tag="LSX49_000871"
     CDS             complement(59310..60146)
                     /gene="eutJ"
                     /locus_tag="LSX49_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HBL7167314.1"
                     /translation="MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGDEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCMQPGVAALFCKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLY
                     AK"
     gene            complement(60157..61560)
                     /locus_tag="LSX49_000872"
     CDS             complement(60157..61560)
                     /locus_tag="LSX49_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HBL7167315.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPPAAVHEMGVFASLDDAVAAAK
                     VAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGPTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNLAIVAAGGPENLLVTVTNPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQSVLLKNIDERGKGTVSRDWVGRDAAKIA
                     AAIGLKVPEQTRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            complement(61572..61859)
                     /gene="eutN"
                     /locus_tag="LSX49_000873"
     CDS             complement(61572..61859)
                     /gene="eutN"
                     /locus_tag="LSX49_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HBL7167316.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPQGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            complement(61966..62259)
                     /gene="eutM"
                     /locus_tag="LSX49_000874"
     CDS             complement(61966..62259)
                     /gene="eutM"
                     /locus_tag="LSX49_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBL7167317.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            complement(62298..63314)
                     /gene="pta"
                     /locus_tag="LSX49_000875"
     CDS             complement(62298..63314)
                     /gene="pta"
                     /locus_tag="LSX49_000875"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL7167318.1"
                     /translation="MIIKRCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLVE"
     gene            complement(63311..64114)
                     /gene="eutT"
                     /locus_tag="LSX49_000876"
     CDS             complement(63311..64114)
                     /gene="eutT"
                     /locus_tag="LSX49_000876"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HBL7167319.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLGFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLGE
                     QAIVGLSDEDLHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVTKQPLTVKQIQQRLGETQ"
     gene            complement(64111..64812)
                     /gene="eutQ"
                     /locus_tag="LSX49_000877"
     CDS             complement(64111..64812)
                     /gene="eutQ"
                     /locus_tag="LSX49_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HBL7167320.1"
                     /translation="MKKLITANDIREAHARGELAMSVVLRASIITPEAREVADLLGFT
                     ITECDESIPVTASVPASASADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGALQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            complement(64787..65266)
                     /gene="eutP"
                     /locus_tag="LSX49_000878"
     CDS             complement(64787..65266)
                     /gene="eutP"
                     /locus_tag="LSX49_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HBL7167321.1"
                     /translation="MKRIAFVGTVGAGKTTLFNALQGNYTLARKTQAVEFNDNGDIDT
                     PGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            complement(65279..65614)
                     /gene="eutS"
                     /locus_tag="LSX49_000879"
     CDS             complement(65279..65614)
                     /gene="eutS"
                     /locus_tag="LSX49_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HBL7167322.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
BASE COUNT        15725 a        18092 c        16512 g        15413 t
ORIGIN      
        1 tctttcaatc cccttttaaa attgtggttt ttcctcaaaa aaggcctgct ggtcatcagc
       61 cttcaggtta cctatcatag aggtttaatc cttattcaga gtcacccgtg cacgaaatat
      121 tcaacatgct gctggcggtc ttcgatcggg cagcgttaat gcttatctgc ctgttctttc
      181 tcatccgtat ccgcctgttt cgcgaactgt tgcacaagtc ggcgcactcc ccaaaagagt
      241 tgctcgccgt taccgccatt ttctcgctgt tcgccctgtt cagcacctgg tccggcgttc
      301 ccgtagaagg ctcgctggtg aacgtacgta ttatcgcggt gatgtcaggc gggattctgt
      361 ttggcccgtg ggtgggcatc attaccggcg tgattgcggg tattcaccgt tatttaattg
      421 acatcggcgg cgtgacggcg atcccctgct ttatcaccag cattctggcg ggttgtatat
      481 cgggctggat caacctgaaa atccccaaag cacagcgctg gcgcgtcggt attctcggcg
      541 gcatgttgtg tgaaacgttg accatgattc tggtgattgt ctgggcacca actaccgcat
      601 tggggatcga tatcgtctct aaaatcggga ttccaatgat cctcggcagc gtctgtatcg
      661 gctttattgt gttgctggta caaagtgttg agggagaaaa agaggccagc gccgcgcggc
      721 aggccaagct ggcgctggat atcgccaaca aaacgctgcc gctgtttcgc catgtcaata
      781 gcgagtcatt acgcaaggtc tgcgaaatta tccgcgatga cattcacgcc gatgcggtgg
      841 cgatgactaa taccgatcat gtgctggcct acgttggcgt gggtgaacat aactatcaga
      901 atggcgatga cttcattagc ccgactaccc gtcaggcgat gaattacggg aaaatcatca
      961 ttaaaaacaa tgatgaagcc caccgcacac cagagattca ttccatgctg gtgatcccat
     1021 tgtgggagaa aggcgttgtg accggaacgc tgaaaattta ctactgccac gcgcatcaga
     1081 taacctcgtc attacaggaa atggcggtcg gtctgtcaca aatcatctcc acgcaacttg
     1141 aggtgtcacg cgccgagcag ctacgtgaaa tggcaaataa ggcagagctt cgcgccctgc
     1201 aaagcaaaat taatccccat ttcctgttta acgctttgaa cgctatttca tcgtcaatcc
     1261 gtctgaatcc ggatactgct cgccagctga tctttaattt gtcgcgctat ctgcgctata
     1321 acattgaatt aaaagacgat gagcaaatcg atatcaaaaa agagctgtat caaattaaag
     1381 actatattgc cattgagcag gcccgctttg gcgacaagct gacggttatc tatgatattg
     1441 atgaagaggt gaattgctgc attcccagcc tgctgatcca gccgttggtg gaaaacgcca
     1501 ttgtccacgg tatccagcct tgcaaaggta aaggcgttgt caccatcagc gttgctgagt
     1561 gcggtaatcg ggtacgcatt gcggtgcgag ataccgggca cggcatcgat ccaaaggtga
     1621 ttgagcgggt cgaagcgaac gaaatgccgg gcaataaaat tggcctgctg aatgtccatc
     1681 atcgcgtgaa gttattgtat ggcgaggggc tgcatatccg ccgcctggaa ccaggaacgg
     1741 aaattgcgtt ttacattcct aaccaacgca ccccagtcgc ctcacaggct accttattgc
     1801 tttgagccgg agtgatattg tgaaagtcat cattgttgaa gacgaattcc tggcacaaca
     1861 ggaactgagc tggctaatta aagagcacag ccagatggag attgtcggca cctttgacga
     1921 cggtctggac gtgttgaagt ttttgcagca taaccgcgtc gacgccattt ttctggatat
     1981 caatattccg tcgctggatg gtgtgttgct ggcacaaaac atcagccagt tcgcccataa
     2041 accgtttatt gtgtttatca ccgcgtggaa agaacatgcg gtagaagcgt ttgaactgga
     2101 ggcgtttgac tacattctca aaccgtatca ggagtcacgc attaccggga tgctgcaaaa
     2161 actggaagca gcctggcaac aacagcagac cagcagtacg cctgccgcga cggtaacgcg
     2221 tgagaatgac accattaatc tggtgaaaga tgagcgaatc atcgtcacgc ccattaacga
     2281 tatctattac gccgaagcgc atgagaaaat gacctttgtc tatacgcggc gtgaatccta
     2341 cgtaatgccg atgaacatta ccgagttttg cagcaagctg ccgccgtcgc attttttccg
     2401 ctgccatcgc tcattttgtg tcaatctgaa caaaatccgc gagatcgaac cgtggtttaa
     2461 taacacctat attctgcggc tgaaagatct ggattttgaa gtgccggtca gctgcagcaa
     2521 agttaaagaa ttccgccagt taatgcatct ttaatcggga actttcatga aagcaccagg
     2581 cttgcccgcc gatcaacaat ttttcgccga tctgttcagc ggcctggtgc ttaacccgca
     2641 actactgggg cgcgtctggt ttgccagcca gcctacctca ttgccagtgg gcagtttatg
     2701 tattgatttt ccccgtctgg atatcgtgct acgcggcgaa tacggcaatc tgctggaagc
     2761 aaagcagcaa cgtatggtgg aaggagaaat gctgtttatt ccagcacgcg cggctaattt
     2821 accggtcaac aacaaaccgg tgctgctgtt aagcctggtg ttcgcaccga cctggcttgg
     2881 gttatcgttt tacgatagcc gcaccacgtc gttgttacat cctgctcgcc agatccagct
     2941 tcccagcctg caacgcggtg aaggtgaagc gatgcttacc gccctcaccc atcttagccg
     3001 ttcgccgctg gagcagaata tcattcagcc actggtgtta agtttgctgc atctttgccg
     3061 caacgtggtg aatatgccgc cgggcaattc gcaaccgcgc ggcgattttc tctatcacag
     3121 catttgtaac tggattcagg ataattatgc ccagctgctc acccgcgaga gcgtggcgca
     3181 gttttttaat atcacgccaa atcatctgtc aaaactgttt gctcagcatg gaacaatgcg
     3241 ttttatcgag tatgttcgct gggtacgaat ggcaaaagcg aggatgattt tgcaaaaata
     3301 tcatctgtcg attcatgaag tggcgcagcg ttgcgggttt ccggatagcg actatttttg
     3361 tcgcgttttc cggcgtcagt ttggtctgac gccgggagag tatagcgcac gttttcaggg
     3421 ctaacgtcag aaggttaatt ccgtttccag cagcgtcaga atactttgtg catcttgcgc
     3481 ggcaaacagc gactggcgga agtttttatt caccagttta cgcgccagct gcgagaagac
     3541 tttcacatga ttcatccctt cgttagcgcc cagcgtcagc atgatcacca gttcgacttc
     3601 gcccatttct gactgccagt caaccggttt caccaaccgg gcaatgctga tactggaatg
     3661 acggatccac tgtgatttgg tgtgcgggat cgccacgcca aaaccaacgc cagtagtaac
     3721 aatctcttcc cgctgccaga catcttcttc cagctcgaac ggatgttcag tacgcccgtt
     3781 aacaccgagg ttaccgcaca ggaactggat cgcctgctct ttattactaa aggactgatc
     3841 aacaaagata ttctctagtg ccagcagtgg gcgaacgtct tcttccggcg caaacgcggt
     3901 aagtaacgct tcaatttcct gcgcgctgcg gcactcgcac gcctgacgcg ccagttcccg
     3961 acacgcctcg ctatccagtt gacgaagctg gcttttcact gccggaatac gcgggctact
     4021 catgcttagc tcatccagcc ccagccctag cagtagcggc agataacgac tttcaccgcc
     4081 cagttcaccg caaataccta cccatttgcc gcgctgatgc gcagcggtaa caatctgctg
     4141 caacatgcgc aggaacgatg gcgtaatcgg gttatacagc ggcgatacgc gcgggttatt
     4201 acgatcgact gcatacagat actgggtcat atcgttagaa ccgatactga agaaatcgac
     4261 ctcatcgcag aagtggtcga tgatgtagca caccgacggc acttccacca tgatacccag
     4321 cgtaatcgtc tctgcatgac gcaggccatc gcgcttaagc tcaacgatcg ctttttggat
     4381 ctcacccttc acccataaga tctgatcgag actgtggacc attgggatca tcaactgggc
     4441 gttgccgaaa ctggcagcgc gcaaaatcgc ccgcaattga gtgcggaaca ggccagcaaa
     4501 ttccgggtaa atacgtaccg cgcgatagcc gaggaacggg ttctcttcct ggggaatgtt
     4561 gaggtaagga atgcttttat cgccaccgat gtccatcgtg cggaagataa tcggcttgtc
     4621 gcccgccgcc aatagcacct gctggtacgc ttcaaactgt tcctgctcgt ccggcgcgct
     4681 gtcgcgatcc atatagagca tttcggtacg aaacagccca acgccttccg cgccgttagc
     4741 aaacgcgcct ggggcttcca gagcggtgcc aatattcgcc gcaatatcaa tacgtttgtt
     4801 atcacgggaa taggccagct gcgcggcagc ttgcgcctgt tgtttttggc gtttatccgc
     4861 cagcgtctgc gcgacctgat aataaccgct caccgcgtca ttcgggttaa tcgccagcac
     4921 gccgcactgg gcgtcaagca ctgcaggttg cccggcataa cgggcaatcg catccagcgg
     4981 cagtccgctc agtaccggga tcgccgaagc gcgggccagg atcagggtat gcgaggtgcg
     5041 cccggttttc tccagaatca tgcccgcaag attttttaaa tcgaggctca aaaactggct
     5101 tggggttaaa tcttcagcca ccagaatggt cagtttttca agcaccagat tattgcgcgg
     5161 ttttagttcc ggccaggtga tatgcagcaa ctgttcgctg atatcgcgaa tgtcgctgac
     5221 ccgctcgcgc agataatcgc tggcagaagc agaaagtttg gcacaaacct gctccatatt
     5281 gctgatgatc gccgccccca gcccctgatg ctgttctgcc atcaggtgac ggatattgcc
     5341 tgcaaattca tcatcctgaa tcagcgacaa atgggcgctg aggatagttt tgctttcgcc
     5401 gtcacgctca cgcaattgct ggttcagttg ctcggcaagc gttgccagac tgtgctccag
     5461 tagggtggaa tcttgcgcac tcgcagggat cacccgataa ctgtcgaggc tgtcgctctg
     5521 taacagggtc agtgtaccca cgccaacgcc gcttgccagc acgttgccgt acagtaaatc
     5581 cgggttcagg cggcttaatg aacgcggcag cggatgcgcc gtcagttctg ccagcgtcgg
     5641 ctggacgcta tcgctgtcga taaagcgcac ctggatatac tcttccagca ctcgccgcgc
     5701 ctgctcttca tcgctaccgc taatgttcag gctgcaactg tcattaaata aagtgccagt
     5761 gccaatcagc gccagcgagc ttttcgcatc ggcctttgcg ttctggcgat ggttaataaa
     5821 agtgatttcg ctttgccact ggctgcactg ctctttaagt tcccacgccg gacgagcatg
     5881 tagaccgtta ggcaaaggac agagaaattg aatcgttaac ataaccgctc cgggttaatc
     5941 aggagatcat ctgaaatccg tcagttgaac aaccgtctca cgcgtaagac gttgaataag
     6001 ggcagataaa agttgctcca tctgcaaaat gtcacggcag tcagcaatcg atgcggcgca
     6061 atgtccgtgg cgggttgcag gccccatcac cactgtgggt acgccagtgc cggttaagtg
     6121 caccgcccca ccgtccgtgc cgccattgct gaacatatct gactgcaacg gtacgccaat
     6181 ttctgccgcc acggtttcga tccaggcggt aagttttggc ggcgcaatca gtgacttgtc
     6241 gcttaacacc agcatcggcc cgttaccaat ctggcgatgg ttagctgcgc cataatcaaa
     6301 gtttttcgcc cagcaggcag tatcaagcac aatggcgaca tccggcgaca ccgcgcgggt
     6361 ggcagtttgc ccgccgcgta atcccacctc ttcgctggaa cttgccacca gccacacttc
     6421 cgcaggcagt tcggcgtcgt gcagctcacg cagtaacgtc accagcagat agcaaccgag
     6481 gcggtcatca aaggctttcc ccatcacccg ctggtgaggg agaacctgaa aagtggtatc
     6541 gaaggtgacg cgatcgcctg gacgaattcc tgcctgcatc acttcgtcac aggagcgcgc
     6601 gccaatgtcc acgcgcatgg cgctgacgtc attcccctgc cggtcgctgt caagcaggcc
     6661 tggaattttg cactcttcac gggtagtgat acgcaccgac tgaagctggc gggcagccat
     6721 gcgtacattg ccaaccggca acacatcgat cgccccttcg cgggagatgc tgcgcaccat
     6781 aaatcccact tcgtccatat gcgcacagat catcaccttc ggacctgtcg actcattgag
     6841 tcggatcagc accgatccca ggccgtcaaa tcgcacttct ttttgcaggc gatccgcttc
     6901 ttcccgcagg atctgccgta cttcctgttc tgaggaggcg atcgcatctg cctcgctcaa
     6961 cgcttttaag agcgataaat ccattatgcc tctcccgtga gcaacactgt tttcggcacg
     7021 gcgtagagca cttctgcgcc ttgcggggtg accagcacga catcttcgat gcgcacgccc
     7081 ccttgccctg gcaaataaat ccctggctcc acggtcagta acatacctgg ctgtagcgtc
     7141 gtggtgtccc gcggtgaaaa acgcggttct tcatggactt caataccgat agcatgaccg
     7201 gtgttatggc cgaaaaactt gccataaccg gcctcggtaa tcacgcggcg cgcggcatcg
     7261 tcaacctgct ggcagcgcac gccggggcga attacagaga ttgccgcgag ctgtgcctgc
     7321 aggacaatct gatagacgtt aaacagcgga tgagattcgg cgctcacccc ttcgccattc
     7381 accagcaagg tgcgcgtcat atcagagcag tagccctgat acagcgcacc gaaatcgaga
     7441 gtgacaaact cgcccgctgc aacaatcttg tcgctggctt tgccgtgcgg cagcgcccca
     7501 cgccagccgc tggcgacaat ggtgtcaaaa gaggcttttt ctgcgccctg ctggcgcata
     7561 aaccactcca gttcagcggc tatctcgcat tcgctcattc ccgcctgaat aaagcggcga
     7621 atatgctctg cgccacgatc ggcaatcccg caggcaaggc ggattttctc cacctcttct
     7681 ggcgttttga tttgccgcag cacatccggc gtggcgctca ccagtttcgc attgagttcg
     7741 gactgccagc ggtgcgcggt ttcccaactc acctgctggc cttcaaaacc gagcgtttgc
     7801 aactgctcat cggcaatgat ttgtctgacg atggtggcaa gcgtgtgcat cgcgtcgagc
     7861 aaatgcagct ggtaaccttg cgtgcgggct tctacatccg cgtaatagcg cgaatccacc
     7921 agaatgtgcg cactttcacg gctaatcacc acataacctg atccggtgga gatccccaga
     7981 tgcggctgtt tgttctgccg tgaggagaga agcaccgcat ccagttgttg cgccttaagc
     8041 cagtcgcgca gcgaagcgag taatgtcatc aggattgtcc ttcttacagg ctatcgatta
     8101 acaatttgcc tttacggaac atcatcagac gcaggaacac caccatcagc gcagttatga
     8161 ctgcccccag cgcgatcccc gccatgtaga cgccgaggtt agtgaccagc ggccatgccc
     8221 agatagcgga ctccgggaac cattgcactg cgcccagcca gacagcggcg gttgagccga
     8281 caatcgcgcc gaccatatac gacggaatgg cggtgatagg gctttccagt gcaaacggaa
     8341 tcgcaccctc actgatcccc ataaacgcca ggaacatggc ggttttaccc tgcggataaa
     8401 gctgggcgtt gaacaagcgt ttgccggtta aacgacggtc aataatggtc gccagaccca
     8461 gaccaatcgg cggaataacg atagcgatag aacgtgcagt gaccggtaat acgtggtcag
     8521 tggtaaagct gaaggcaacg aaacctgccg ctttgttgat cgggccacca aggtcgattg
     8581 ctgtcgccgc ggcgatcccc attgcgtaca tcagtgcgcc cttctcacct gcagcggtca
     8641 gcacggtacg gataccgccg ttgatccagc caccaaaggg ggtgatgacg tagtacatcg
     8701 ccagcatgac aaaaatggcg gaaagaatcg gtagcaaaaa tgtggttttg aacgctaaca
     8761 ggaaatccgg taactggatt ttctggttca tccatttcac aaggtaaccg gcaacgatag
     8821 aaataatcag cgcaccaatg aaggtggacg gcaccggcga agaggtcgcc cattgcatag
     8881 tgctgggatc gaagttcagc agttgcgtcg gctgggtaga catcaagccg ccgataaaac
     8941 cagccgggaa cgccagtttg ccaccgatag agttcgccac aaaagcagca aacatcggaa
     9001 ttgcaaaacc aaacaacacg ccgccgaagg actgcgacag ccaggcaaat ttaagtaagg
     9061 agaggtcgaa accggagaat ttcccgctat taagagcatc catgatgccg atatcagcag
     9121 gaattttaag ccagctataa gcaatcagct gactgaaagc gaggatcaca ccgcccataa
     9181 ttaaggtcgg caccatgcgt gaaatccctg acatcacatg ctgcgggagt tcaccccaga
     9241 agctggattt agaggcctgc ggattcttaa ctgccgctgc cgcaccggat gcgccatgca
     9301 caacggttgc actgcgtttt ttaatggcca taacaattat ccctgtcgaa tattactgtt
     9361 gttcagaggc aatcatctct tcgatttctt tgatgattcc cgcagcgttt ttaattgcgt
     9421 cctgcaaagt gatttcataa acgtcgcgtg attcgaaacg ctcgttatct tccggggtaa
     9481 ctgccacgga gtggatgatg atggtcgctt cggcgatatc ctgcgccgtc aggcgattct
     9541 ggataccgtc cgcgccctgg gtttcaattt tcacttcata accggcttct accgccgctt
     9601 cttccagcgc ctgagcggcc ataaaagtgt gagccaggcc cattgggcag gcacataagg
     9661 caatcagttt cttactcatc gttaattcct cgttcagtga tagttgacga gtgaaattat
     9721 gaacgtgcaa aacaaatcgc cgttaccaga caaataatgc atttactgga gaattaatcc
     9781 cgctgtacgg aagtgtgacg caggtcggcc ttgtgagggg acacaaagaa aaatttaatt
     9841 aactgtatga tttaaaagat tatcgggaga gttacctccc gatataacag gaaggattta
     9901 gagaatgtga cctaaggtct ggcgtaaatg tgcaccggaa ccgagaagac ccggattgtc
     9961 atggacgatg agatataccg gaatatcatg gacatattcc ttaaagcgcc ctttatcttc
    10021 aaatgcggcg cggaaaccag aggctttgaa gaactcaaga aagcgcggca cgataccacc
    10081 cgcaataaac acgccgccaa atgtcccgag attgagcgcc agattgccgc caaaacggcc
    10141 cataatgacg caaaacagcg acaacgcgcg gcggcaatcg gtgcagctgt cagccagcgc
    10201 gcgttcggta atatcttttg gcttgagatt ttctggcagg cggttgtcgg ctttaacaat
    10261 tgcgcgatac aaattcacca gcccagggcc agaaagcacg cgttccgccg aaacatgacc
    10321 aatttccgca cgcaatattt cgaggataat gccctcttct tcactattcg gcgcaaaatc
    10381 aacgtgaccg ccttctcctg gcaagcttac ccaacgctta tcgacatgga ccagatgcgc
    10441 aaccccaagc cctgttccgg caccgtaaac cgcaataggc ttaccttcta ccggttctgc
    10501 gccaccaaac tgaatcagat gctctttttt cagcatcggg atcgccatcg acacagcagt
    10561 aaaatcgtta ataatttcca gatggctaaa accgagattc tttttcattt cggcaattga
    10621 gaacgcccag gtatggttgg tcattgccac ccagtcaccg gtaattgggc aagcgatggc
    10681 aatacagccg tctttcacct cgaccttatg ttcttcaaga taaacgcgaa tgaccgcttc
    10741 gaggctgggg taatcaagcc ctgaataggt cttagcctgc gagatttcac cactggcaat
    10801 atcacacaga gcaagacgtg cgttggtgcc gcccacatca ccgactaatg catactttgt
    10861 cattcttcaa ctgctccgct aaagtcaaaa taattctttc tcacactgta aatacctggg
    10921 ggcataacaa caacgccgga aaggcaggct ccctgtaaat atcgatctgg gtcacacaat
    10981 tactttatcg tttcagcacc aattgcagcg atgccttttt gcaagctggg caaactaagt
    11041 atctgacccc gcataaggaa tagaacatgc tccatccgcg agccagaacc atgttgttat
    11101 tatcgctccc cgccgtggca attgggattg cgtccagtct tattctgatt gtggtgatga
    11161 aaatcgcctc ggtattacag aatttgctct ggcaacgact gccgggaact ctggggatag
    11221 cccaggattc acctctctgg atcatcggtg tattaacgct aacgggtatt gcggtggggt
    11281 tggttatccg tttcagccag ggtcatgccg gaccagaccc cgcctgtgaa ccgctgatcg
    11341 gcgcaccggt tccgccctct gcgctaccag gacttatcgt agcattaatt ctcggtcttg
    11401 ctggcggcgt cagcctgggg ccggaacatc cgatcatgac cgtcaatatc gcccttgccg
    11461 tcgccattgg cgctcgtctg ttaccgcgcg tcaaccgaat ggagtggact attttagcct
    11521 ctgccggaac catcggcgcg ctgtttggca cacctgttgc ggcggcattg atattttcgc
    11581 aaaccttaaa tggcagtaat gaagttccgc tatgggatcg tctctttgcg ccgttaatgg
    11641 cggcagcagc tggtgcactt actaccggat tatttttcca tcctcatttt tcactgccca
    11701 ttgcgcatta cggacagatg gaaatgaccg atattctcag cggtgcaatt gtcgcggcga
    11761 ttgccatcgc agcagggatg gtcgccgtat ggtgcttacc acggttgcac gcgatgatgc
    11821 atcaaatgaa aaatccggtg ttcgtgctgg gtattggcgg atttattctc ggtattctgg
    11881 gggttattgg tggaccggtt tcgctgttta aagggctgga tgagatgcag cagatggtgg
    11941 caaatcaggc tttcagcacc agcgattact ttttgctggc ggtgataaaa cttgccgccc
    12001 tggtcgttgc tgccgccagt ggctttcgcg gtgggcgaat cttcccggca gtgtttgtcg
    12061 gcgtggcatt agggttgatg ctgcatgagc acgtacccgc cgttccagcg gcaataaccg
    12121 tttcctgcgc tattctcggc atcgtgctgg tggtaacacg tgatggctgg ttaagtcttt
    12181 ttatggcggc agtcgttgta cccaatacca cattgctacc gctgctctgt atcgtcatgc
    12241 tcccggcatg gctgttatta gcaggtaagc cgatgatgat ggtcaatcgt ccgaagcaac
    12301 agccacccca cgataacgtt tagcaaaaaa tgctctcctt tatgatttaa gagttatggc
    12361 gatgatacgg cgctttacct ccccgtaata ttgcgttaac aggccgctga cggcttcgat
    12421 cgtgaaggag aataacaatg ttcaggtcac tgtttctggc ggccgccctg atggcattta
    12481 ccccgcttgc ggcaaacgca ggtgaaatca ccctactgcc atcaatcaaa ttacaaattg
    12541 gcgatcgcga tcattacggt aattactggg acggtggtca ctggcgcgac cgtgactact
    12601 ggcaccgcaa ttatgaatgg cgtaaaaacc gctggtggcg tcatgataat ggctaccatc
    12661 gtggctggga taagcgtaaa gcgtatgagc gtggctatcg tgaaggctgg cgcgatcgtg
    12721 acgatcatcg tggaaaaggc cgcggacatg gacaccgcca ttaaacacat tcgccaatgg
    12781 agcacaatgc ctgatgcgac gctagcgcgt cttatcaggc ctacaaacca gctctttaac
    12841 gcgtagggcg gataaagcat ttacgccgca tccgccaatg gtgccaaatg cgacgctcat
    12901 tcaactacaa tcccagtgcc gttcctacca gtaaccagat attcagcgcc actaccagca
    12961 ccacaatcac ccagcctgtc tgttttacgc gtttgctgtt caccagatcg cccatcaact
    13021 tgctgtcact ggtgaaaatc aacagtggaa ccagcgccag ggcgatacca aaacttaaca
    13081 gcacctgact cataaccaga atccgtgtcg gatctaatcc catcagaatg acaataaatg
    13141 acggcagcat ggtgacagta cgacgcaccc acagcgggat atgaaagcga atgaagccct
    13201 gcatcactac ctgccccgcc agcgtcccca ccaccgttga ggacaacccg gcagcaacca
    13261 ggcttaatcc aaagaccgtt gccgcagcat ggcttaacag cggttgcagc gtcagataag
    13321 cctcatcaag atcggcaaca ccagtatgac cagaaaagtg gaacgccgcc gcagctgtag
    13381 ccatcatcgc cagattaaca aaaccggcaa tcgtcatggc gatagccaca tcccatttgg
    13441 tggcggaata acgttgttga cgcgaaccgc catgtaaatg ctgagtgagc gaagagtgca
    13501 aataaatcac atgcggcata atcgtcgccc ctaacacgcc cgcggccagg aagaccgcct
    13561 ccgaagtagg taaactcggg atcaccattc ctttacccag ctgcgccagg ttaggctggg
    13621 agaaaatcaa ctcgacaatg taagcagcgg caacaaacaa cagtaacccg ccaatcactt
    13681 tctccagcgg tttttgcccg cgacgttgca gcattaaaat aaggaaagtc gcgatccccg
    13741 tcagcaccgc gccctgcaac aacgaaacac caagaatgag tttaaaaccg atcgccgcac
    13801 caataaattc cgccaggtcg gttgccatcg caataatttc tgcctgaacc caatagaacc
    13861 acactacggg acgcggatag tgatcgcgaa tctgctccgc cagattttta ccggtggcaa
    13921 tccctagttt ggcagagagg atttgaatca gcatcgccat caggttagcc caaacgacaa
    13981 cccacagtag ctgatagccg aagctggcac ccgcctgaat attggtcgca aagttaccgg
    14041 gatcgatata accaatcgcc gcaatgaacg caggtcccat taatgcgagc ctcatcttgc
    14101 gcgccgcccg tccgctgcta ctctcaacgc gatagttcgt catcttgtgc ctctaaaaca
    14161 tagcctttgc tatgtttcat gctacgttaa atgagaatga ttatcaaatt catttaaatg
    14221 ggttgtgatg atttctctga tagaccagga ttatgactac gaaaagatag atgactcgaa
    14281 tgttatggtt atgtttaata ttagcacatt tacataacct tccgcttcca tacacaacat
    14341 agcagaaatg tatgacagat cactattttt gaagcttgtc acaggacgtc attatagtgt
    14401 gtgtcagatc tcgttttcct taaccatgtt acatagaatg tgcacggaaa tttaacctgc
    14461 ctcatatttg gagcaaatat ggaccgcgtc cttcattttg tactggcact tgccgttgtt
    14521 gcgattctcg cactgctggt aagcagcgac cgcaaaaaaa ttcgtatccg ttatgttatt
    14581 caactgcttg ttatcgaagt gttactggcg tggttcttcc tgaactccga cgttggtctg
    14641 ggcttcgtga aaggcttctc cgaaatgttc gaaaaactgc tcggttttgc caacgaaggg
    14701 actaacttcg tctttggtag catgaatgat caaggcctgg cattcttctt cctgaaagtg
    14761 ctgtgcccaa tcgtctttat ctctgcactg atcggtattc tccagcacat tcgcgtgttg
    14821 ccggtgatta tccgcgcaat tggtttcctg ctctccaaag tcaacggcat gggcaaactg
    14881 gaatccttta acgccgtcag ctccctgatt ctgggtcagt ctgaaaactt tattgcctat
    14941 aaagatatcc tcggcaaaat ctcccgcaat cgtatgtaca ccatggcagc aacggcgatg
    15001 tccaccgtgt cgatgtccat cgttggtgca tacatgacca tgctggagcc gaaatacgtc
    15061 gttgcggcgc tggtactgaa catgttcagc acctttatcg tgctgtcgct gatcaaccct
    15121 taccgtgttg atgccagtga agaaaatatt cagatgtcca acctgcacga aggtcagagc
    15181 ttcttcgaaa tgctgggtga atacattctg gcaggtttca aggttgccat tatcgttgcg
    15241 gcgatgctga tcggctttat cgccctgatc gccgcgctga acgcactgtt tgccaccgtg
    15301 actggctggt ttggctacag catctccttc cagggcatcc tgggttacat cttctatccg
    15361 attgcatggg tgatgggtgt tccttccagt gaagcactgc aagtgggcag tatcatggcg
    15421 accaaactgg tttccaacga attcgttgcg atgatggatc tgcagaaaat tgcttccacg
    15481 ctctctccgc gtgcggaagg catcatctct gtgttcctgg tttccttcgc taacttctct
    15541 tcaatcggga ttatcgcggg tgcggttaaa ggcctgaatg aagagcaagg taacgtggtt
    15601 tctcgcttcg gtctgaaact ggtttacggc tctaccctgg tgagtgtgct gtctgcgtca
    15661 atcgcagcac tggtgctgta agaccataca taaaaaagcc ggggataatt ccccggcttt
    15721 tttacgcctg ttaatcggct aatggctgcg ggcgaccaat caaataccct tgcagatatt
    15781 gcaccccgag cttatgcaat agcgcctgct gctgttgcgt ctcgacaaac tccgcgacca
    15841 cactcaatga cttcgctttc gccagatcgg taattgatct cacaatcatc gcatccagcg
    15901 tgttcgtgac gatatctttc acaaagacgc catcaatttt gatgatatca gcctgcaaac
    15961 gctttaaccg ttcgtagttg gcatatccgg tgccaaagtc atcaatcgca atccggaaac
    16021 caaacttatg cagctgctcg atgttgtaca tgctgctttc tgcgttagaa aacgcctgct
    16081 cctcggtgat ctcaagaatg accgcctgcg gggagatgta ataacgctta aacagacgaa
    16141 taatccgccc ggcaatattc ttttgcagca gcgtgagcgg cattaaattg actgaaaatc
    16201 gtggaccttt tttgtcgcaa gggtgtgttg ccagccactt caacaaggat tccagcactt
    16261 gcaaatcaaa acgcgcgcta aggttaaact gagcaataag gggcagaaac ttatccgggg
    16321 tcataatgcc gccgtcatac ttcagtcgcg cgaggatctc atcataacct tcaccctctt
    16381 tgttgcgaat tggctgggcg tagagcagca aatcaccctg atctaacgcc gtgcgaatgg
    16441 tattcagcaa tagcacctgt ttagtggttt gcccggaaac catctcctct ctgctatcca
    16501 gcgccagcac atgatgatgt gcgcaggatt gctctgccag ccagcttaac tgccccaaca
    16561 agggttgcag ggtttcctga tttccatcaa aatgccccca ggcagcacca tagcccatat
    16621 ccagcccggt attgttccag tgaatttgcc gactattcag gatgttaacc atatgctgga
    16681 gtcgcccttc cgtttccggc ccgctcagca ctaacagcag ttcactaccc ggcaattgat
    16741 acaacttttc gttttcctgc atcaacggca gcaacgtacg gtaaattgag cggatacagt
    16801 gaacgcgcat cattaagccg taatgacgac tcataaactc aagattatca atgcgcaggc
    16861 agcaaaaact cttgcccgcc tcttgctccg gtgcttgttc caacgcacga aagttgggta
    16921 ggagcgttaa cggatcggtc agcgcctgca aatgccagcg gcggttaagc cattcactac
    16981 gatgataaat acgcaccata tagagcagac aaacactaaa ggaaatcagt actgcgagaa
    17041 taaatgccag cgaatattcg gttagtaccc cttgcaaaaa gttctggttg taattcagca
    17101 ggcaaagcgt tgaaacagcc caggtgagat ttaaaaacgg atagcgaagc ttaccgacac
    17161 cgagggtaaa gatgataaag aaaacaggta ccaagtaacc ggcaataaag tcattttcat
    17221 acggtgtgca catcagaagt agcagcacgc taagagctgc cagccagctt aaggtaaatg
    17281 cgcgtttctc tttgctcaac gacggagcga tatccctacg ccacaatatc tgtgcaaagt
    17341 ggggacttac aatcatgcgg gtgagatagt aaaaaagcat gttgtaaatc agcactgcgg
    17401 tgaaaaggct tagcaaatca acgaccgtga aaatggcatc cgcatcgccg aaaaaggtag
    17461 atatctttag cggaaaatca aagaaatttc ccacaagata catgctgcat ttgatgccaa
    17521 tcggcgccac caaaccaagc cagaacagac gttgccagac gtatcggctg gtcaatccat
    17581 aacgccaacg cgtccccaat tgccagcgta atattgcaca ggcacacagg actgcaaacg
    17641 cctggctgcc gatcatgacg gcggtctgta aaaaagtgag atgaaggttc cacagattgg
    17701 tgcaaaacat cccacataaa atgggaacga caccacgcca gccaaagata aacaagattg
    17761 acagcattac gcacagtggc atccacgcca gaaagatata attggaatgg ataacagcaa
    17821 gtggcgaaat taaacgggat agctgaataa gtaccacggt gagcgtaaac gctagtgtga
    17881 atatcttgat attttttatc aggttatgct ccacaaacat gagtacacta ctctcactga
    17941 tcggggtttt caggcacaca aataataagt ttattcgcat cgcgaagcaa acaggggcca
    18001 gcctgttgct gtttttgcag tcagtgatgc attcaccaca cggcactgcc aggatgtaga
    18061 ctgtattaca aaagcggcaa aaggcagaga caaaaaaccc ccgctttgca gcgagggttt
    18121 gaaatttggt ggagctaagc gggatcgaac cgctgacctc ttgcatgcca tgcaagcgct
    18181 ctcccagctg agctatagcc ccacgagtcg tttacgtacc aaatttgctg ggtgcaaaat
    18241 ttggtggagc taagcgggat cgaaccgctg acctcttgca tgccatgcaa gcgctctccc
    18301 agctgagcta tagccccatc acgtaaagct tgtcgagttg acgggcggca tcatatgaat
    18361 tccgcccgaa tgtgtcaacg gcaaattgcc acgtgtagtt tcaatcgctg aaaaatcagg
    18421 caaatgaaca attttggaaa accgctcgca ttcagtagtt attcatgtca cggtttcctg
    18481 taaagtggtg ttataaaatg aactactaat agacccacat acattcaggg aattgttatg
    18541 ttcaaggaga ggatgacgcc agatgaactt gccagactga ccggctatag ccgccagacc
    18601 attaataaat gggtacgcaa ggaaggctgg acaacgtcac caaaaccagg cgtccagggt
    18661 ggcaaggctc gactggttca cgtcaatgaa caggttcgtg aatatattcg caatgctgaa
    18721 cgtccagaag gtcagggaga agcgccagcc ctttctggtg atgcgccgct tgaagtgttg
    18781 ctggtgacac tggcgaaaga gatgacgcca gttgaacaaa aacagtttac atccttgctt
    18841 ctgcgggaag ggattatcgg attgttacaa cgcttaggga ttcgcgatag caaataatat
    18901 gaaaagatta cgcaataaaa tgaccaccga agaactggct gaatgcctcg gtgtggctaa
    18961 acaaactgtt aaccgttgga tcagagaaaa aggctggaaa acggaaaaat ttcccggcgt
    19021 gaaaggcggt cgtgccagac ttattctggt cgatacgcaa gtttgcgagt ttattcagaa
    19081 cacgccagcc ttccataaca caccgatgct tctggaagcc gaagaacccc ttgccgaata
    19141 cgcaccgggt attcgcactc ctgcttatcg gcaaatcatc agcgcaatag acaacatgac
    19201 tcacagtgag caagaaaaag ttgcgcaatt tttgtcacgc gaaggaattc gtaattttct
    19261 tgctcgtctc gacatagatg aatcagcata aataaaaaac ggcaggggta tctctcctgc
    19321 cgtttatctt ttatgcgcta attactgctg attttcgcgt tcagcaataa aagccagcgc
    19381 tttgttgata cgctcgatac tgcgggtctt accgattgcg tgaacggtaa catccagcgc
    19441 cggagactgc cccgcaccgg ttacggcgac acgcagcggc ataccaactt tacccatacc
    19501 cacttccagc tcatccgccg tcgcctgaat agcgtgatga acgttttcag cggtccagtc
    19561 agtaatcgca gtcagtttgt cacgaaccac ttccagcggc tggcgcgcta ccggacgcag
    19621 atgttttttc gcggcgtcgg catcgaactc agcaaaatct tcgtagaaat aacggcagct
    19681 ctgtgccatc tctttcagcg tcttgcagcg ttcgcccaac agtttcacca gatcagccag
    19741 ctgcgggccg ttacgggtat cgatattttc ctgctcaatg tgccactgta agtgagtagc
    19801 aacatactcc ggcggcaacg cgttaatgta gtgatggttc agccacagca gcttgtcggt
    19861 gttgaacgca ctggcagatt tgctgacggc attcagagtg aagtatttaa tcatctcttc
    19921 acgagtgaag atttcctgat cgccgtggga ccagcccaga cgcaccagat agttcagcag
    19981 tgcttctggc agataaccat catcacgata ctgcattacg ctgaccgccc cgtgacgttt
    20041 ggacagtttt ttaccgtcat cgccgttgat catagaaacg tgcgcataaa ccggtaccgg
    20101 cgctttcaga gccttaagaa tgttaatctg gcgcggtgtg ttgttgatat ggtcttcgcc
    20161 acggataacg tgggtgattt ccatatccca gtcatcgaca accacacaga agttataggt
    20221 tggggaacca tcggtacggc ggataatcag atcatccagc tcctggttgc tgaactcgat
    20281 cggaccacgg atctgatcgt caaaaacaac agaaccttcc tgcgggttag caaaacgtac
    20341 gacacacggc tcatcatcag cgtgatgctc atgactgtgg cggcagcgac cgtcataacg
    20401 cggcttctca cctttcgcca tttgctcttc gcgcagcgct tccaggcgct ctttagagca
    20461 atagcattta taagctgtgc cctcttccag catctgatcg atcaccgcgt tgtagcgatc
    20521 aaaacgtttg gtctggtagt acggaccttc atcccactcc aggctcagcc agttcatgcc
    20581 atccataatg gcttcgatag cttccggcgt ggaacgctca agatcggtgt cttcaatacg
    20641 cagcacgaac tcaccgccgt ggttacgtgc aaaaagccag gagtaaagag cagtacgcgc
    20701 gccgccaacg tgcagatagc ctgttgggct tggcgcgaag cgagttttga ttttcatgaa
    20761 atggccttac gtttagaaag atgccgacaa ccggcaaatc ctggaaaaat tgagtgggcg
    20821 atattctatc actcccgcct gattcctcaa tgtagttcgg gttgcaacct tacgcattat
    20881 tgttttcgtt gacaaattgc gcaacacggt ctgttttgcg atcatcttgc ttaaatttac
    20941 gacgaacgaa caatttcttt agaaaatgcg ttgactcatt ttgaactctc cctataatgc
    21001 gactccacac agcgggggtg attagctcag ctgggagagc acctccctta caaggagggg
    21061 gtcggcggtt cgatcccgtc atcacccacc aactacttta tgtagtctcc gccgtgtagc
    21121 aagaaattga gaagtgggtg attagctcag ctgggagagc acctccctta caaggagggg
    21181 gtcggcggtt cgatcccgtc atcacccacc actttctcgc cagctagatt tcttgtaaca
    21241 atgtgaagta ccgaagtggg tgattagctc agctgggaga gcacctccct tacaaggagg
    21301 gggtcggcgg ttcgatcccg tcatcaccca ccacttcggg tcgttagctc agttggtaga
    21361 gcagttgact tttaatcaat tggtcgcagg ttcgaatcct gcacgaccca ccaatgtaaa
    21421 aaagcgccct aaaggcgttt ttttgctatc tgcaatttgc gaaattgcct gatgcgcttc
    21481 gcttatcaga ccaactatgt ccggcagttc ccgtgcctct catctactgc gccaacgccg
    21541 ccagcagttt aaccagcgcg ggcgtcacct gctgcgtttc ataaacaata tataagtctg
    21601 ccgggatgcg ttctttgagc ggacggaata tgacaccggg ccagttcatc tgcgcgtagc
    21661 tgtccgctat caatgtgata ccaataccca tactgaccat ggcgagtacc gtttgcggtt
    21721 cattaacttc gcgaataaca accggtgaaa atcccacctg ctggcaaact cgctgcaaaa
    21781 aatcccagtc agtgtacacg ggcggcattg taacgaaata ctcgtcacgt agcgcttcca
    21841 gcgggacggt ggaaaatgat gagagatgat gctcttcagg catcgccacc agaaacgccg
    21901 attcatgcaa ccgtaagctg gtaaaaccag tcggtggttc tgtcgccatt cgccagatcc
    21961 cggcatcaag ttcgcggcgt tccagcaagg ccatttgcat cgcgggcatc ttttcgcgaa
    22021 acagaacttc aacgttagga ttttctctaa ggaatcgccg cataaccggg cgcatccgtc
    22081 cccacattgc cgttcccaca accccgagtt caatccgccc tgcttctccc cgacctattt
    22141 gttcaacccg agccaataca ttatttgcat tcaccagcaa tcgacgcgat tcttccatca
    22201 agattttgcc cgcgtgtgtc agtacgacgc tgcgcgaatg gcgaataaaa agctgcgtgc
    22261 cgagttgatt ttccagctct ttaatatgaa tactgagcgg aggctgagac atatttaaac
    22321 gcgctgctgc gcgaccaaaa tgcaactctt ccgctacggc aagaaaataa cggagcaact
    22381 taagatctgt tctatatacg cgttccataa ttaagtgctc catataataa atacatcgta
    22441 ttaaattatc atggcataaa gtatttcacc accagatatc cgacatacat aaacacgatg
    22501 gataatatac ccggcaatac atttggaaca ggaataggta atcgcacgat tgtaaacaaa
    22561 gcaccaatgc caaaaccaac gccagaagaa aataaaatat ctttcactaa ttaaccttta
    22621 tcataaaagc agccccaagg aacagagctg cgaatccttt taatgtgtaa ctgaacgatg
    22681 cgttatcttt tcagggtcat ggttatattt aaacccaaag aaaaatatca ctgcgaggaa
    22741 aagagcatac cctgcaaaca tcagccaaat ggtatgccaa tcttttacgc catccaccga
    22801 gaagtaatcc actgccatac cgctcagaat cgagccaacc catgcgccga cgccatttac
    22861 catcgtcata aaaaggccct gggcgctggc acgaatgctg gaatcaactt cctgttcgac
    22921 aaagaccgaa ccagaaatat tgaagaaatc gaatgcacaa ccgtaaacaa tcatcgacag
    22981 caacagcaaa ataaacccgg ttggtgatgg atcgccatag gcaaagaagc caaagcgcag
    23041 cgtccacgcc accatactca tcagcatgac ggttttaata ccgaaacgct tcaaaaagaa
    23101 cggtatcgtc agaatgaaac cgacttcagc catctgtgaa actgacagta aaatggacgg
    23161 gtatttcacc acgaagctat cagcaaactc aggattacgg gcgaaatcat gcaggaacgg
    23221 gttgccaaaa acgttggtaa tttgcagcac cgcacccagc atcatggcga agaggaaaaa
    23281 gatagccatg cgtggatttt taaacagcac gaaggcatcc agacccagct tgctggcaag
    23341 cgatgtagtc gcttttttct ccgcaaccgg aatcttcggc aaagtcagcg cataagccga
    23401 cagcagcaat gacgcaccgg acgcgatata cagttgcaga ctactcaatt ccagatgcag
    23461 caagcttact gcccacatgg cgacaatgaa ccccaccgta ccaaaaacgc gaatgggcgg
    23521 gaaagcggtc accgggtcaa gccctgcctg ggcaagacag gaataagaga cgctgttcga
    23581 taacgcaata gtcggcataa acgccatcgc attgactaac atcacccaaa acatcatatc
    23641 cggatcagtt acggatgccg cataaaaaag tacgcccgca cacaccaggt gacacagcat
    23701 gtatgcacgt tctgcacgca gccatttgtc tgcgatgatc cccattatac caggcataat
    23761 aatcgcggcg atccctttgg aactgtaaac catgccaaca ttagcgccgg tgaaatgaag
    23821 ggtattaatc atgtaagaac cgagggtaac cagccagctc ccccagataa aatattgcaa
    23881 aaaggacatt acctttaagc gcaaagcgat gctcataatc gtttccttgt cgcatcatat
    23941 ggcctcactc agtaaggccg tttattgttg ttttactcag gcaattttgc gcagaaagcc
    24001 gcaaataaga ttaataaagt tttgctttga gagttccgct gctgccagcg tttgggcatg
    24061 agaaagcttc acgtcactca gaccttccgc catgttggta atcgcagaga ccgcaacgac
    24121 tttaagttcg caatggcgag ctgaaataac ctcaggcacc acagacatac caacaacatc
    24181 cccaccaata atttgcatca tgcgaatttc cgccgcagtc tcgaaattcg gccccggata
    24241 cgagacgaac acgccctccg tcagagggac cccctcttct ttcgccactt tttgtaacag
    24301 tgcgcggtat tccgcatcgt aggcattcgc cagcgagaag aagcgctcac caaaacgttc
    24361 atcattaaga cccaccatcg gcgttcccgg catggtgttg atgtgatctt tcaatgcgac
    24421 cagactgccg gcccccactt cagggcgcag tgagccagcc gcattggtgc agaacagcaa
    24481 ctcgcagccc agcaacttaa aggtacggat tgcatccgtc atgatggtca tcccacgacc
    24541 ttcgtagaaa tgtccgcgac ctttcatgca caccactggc accccctgga gataccccag
    24601 caccagctca cccgcatgac cgtgtacggt acttaccggg aacccaggca gcttttcgta
    24661 ggaaattgcg accgcgttct caatctgatc ggccagcgcg cccagcccgg aacctaaaat
    24721 aaaggccact cgtggcgtga aatcaggttt ataagtcttg ataatatcta cgcaatacag
    24781 tgggttatga gaaaactgag cctgatacat atatatcctt tttttgtagg ggggaatcta
    24841 acgccttttt ataacgagat tgccctacct cataccaata cacttttttc atgtatccga
    24901 tagttattcg atatcgatat atttatattt tttcactatt aataggctga aaaaactgta
    24961 ttggtactct cctttccctt gcattaacaa tatgccgctt ttaatcaacc tttttattaa
    25021 gcaatcaact aataacgatc ggcataggga attatgctat gaaaaaacat ctttttactc
    25081 tgacactctc ttctgtattg gcgataccag cagtatccca tgcagaattt aaaggcggtt
    25141 ttgctgatat aggtattcat tatcttgact ggactagcag aaccactgag aaatcgtcga
    25201 ccaaatcaca caaagatgat tttggatatc tggaactgga aggcggcgct aactttagtt
    25261 ggggagaaat gtacgggttc ttcgactggg aaaactttta taatgatcgt catgataaac
    25321 cgggtagcga gcagcgttat acatttaaaa ataccaaccg tatttacctg ggtgacaccg
    25381 gatttaatct ctacttgcat gcgtatggca cctacggttc tgcgaatcgt gtaaatttcc
    25441 atgacgatat gttcctttac gggatcggct acaatttcac cggcagcggt tggtggttca
    25501 aaccgttctt tgcaaaacgc tatacagacc aaacctatta taccggcgat aacggttatg
    25561 tcgccggttg ggttgcaggt tacagcttta tgctgggcag tgagaaattc accctcacca
    25621 actggaacga gtacgagttt gatcgtgatg ccacctacgc ggcaggtaat ggcggcaaag
    25681 aaggtctgaa cggtgccgtc gcactttggt ggaatgcaac ttcacacatc accacaggga
    25741 ttcagtatcg ttatgcggat gacaaactgg gcgaagattt ttaccaggat gcgataatct
    25801 actccatcaa atttaatttc tgattgatta ctgccggagc tcccggcagt atgaattcac
    25861 tctatatctg atacaacgga tccccttccc gcccagccat tagcgcattg ccctggtctc
    25921 gtactacgtc ccataacgct tcagcggcgg tggaaagtga acggttcttc ctgcgcacca
    25981 gcatcaactg gcgttcaacc actggcgtaa tgcgctttac caccagtggg ctaccttcag
    26041 gcaatggtag cgccagtgcg ggaagaatac tgatgccgat gcctgcggct accatcggga
    26101 acagcgtcgc cggatgtcca atctcctgca caatattcgc ctgaataccg ttgcgcgcca
    26161 gcgctgcgtc aatcagcggt cggctgcctg acgcgtaatc ctgcaacacc aatttcgctc
    26221 cctgtaatgc ctgccagggg acataatctt ccacggccaa agcgctatcg cgatggcaaa
    26281 gcagaaagaa aggctcggaa agaatcgctt cacattgcag atcgcccact gggccaggat
    26341 cgatgacgat gccaaaatcg acatctccct ggcgaatact ttccatcacc cactgctgcg
    26401 gacgatcgtg caggacaaac tgaatatctg gatagcggcg atggctttca gcaatgcatt
    26461 gcggaataag atgcgcggaa atggtctggc tggcagcgac ccgaactttt ccgctcagtt
    26521 gttgccccat acgcccggta tcgcgcaacg tgctgttaag ttcatccagc agtcgctcaa
    26581 gacgcaaagc caactgctgc cctgcatctg taagcaccac ttcacgcgtg gttctgtcca
    26641 gcaggcgaac accagtatga ttttccagct ccttcacact gtgactcact gccgactggc
    26701 tcaggccgat acgctctcct gcacgactaa aacttttctc ctgcgctact gtgacgaaaa
    26761 cctttaattg ctttaaagaa taattcatct gtttttttca tgaatggatg caataaatca
    26821 attttatttc tcaaactgga agacgcacaa tagaaccatc gatcatctgg agtctttatg
    26881 aaactttttc gtatcctcga tcctttcacc ttaaccctga tcacggtggt gttgctggcc
    26941 tctttctttc cggccagagg cgatttcgtc cccttctttg aaaatctgac caccgcagcg
    27001 atagccctgc tgttttttat gcacggcgcg aagttatcgc gtgaggcgat tattgctggc
    27061 ggtggccact ggcgactgca tttgtgggta atgtgcagca ccttcgtgct gtttccgatt
    27121 ctgggcgtgc tgtttgcctg gtggaaaccg gtaaatgtcg acccgatgct ctactccggt
    27181 tttctctact tgtgcattct ccccgcgacc gtgcagtctg caatcgcctt cacgtcaatg
    27241 gcgggcggta acgtcgcggc ggcggtttgt tctgcgtcag catccagcct gctggggatt
    27301 ttcctttcac cattgctggt tggtctggtg atgaatgttc acggtgcagg gggcagcctt
    27361 gagcaggtcg gtaaaattat gctgcaactg ttgctgccat ttgtgttggg gcatctttcc
    27421 cggccgtgga ttggtgactg ggtgtcgcgt aataaaaaat ggattgcgaa aactgaccag
    27481 acgtccattc tgttggtagt ttatacggca ttcagcgaag ccgtcgttaa cggtatctgg
    27541 cacaaagttg gctggggatc attgctgttt atcgtggtgg tcagttgcgt tcttctggct
    27601 atcgtgattg tagttaacgt ctttatggca cgccgactgg gcttcaataa ggcagatgaa
    27661 attactatcg tcttttgtgg ttcgaaaaag agtctggcaa atggcatccc gatggcaaac
    27721 attctgttcc ccacatcggt gatcggtatg atggtgctgc ccctgatgat tttccatcag
    27781 atccaattga tggtctgtgc ggtgctggcg cgtcgataca aacgccagac cgaacagtta
    27841 caggcgcagc aggaaagcag cgccgataaa gcttaaagcg gacgtttcag gggctggacc
    27901 agttgcgtca gcccctcgat tttaatcagc agcgtgattt gcattagctc accgagcttc
    27961 cctgccggga actcatcttt gcgggcaaac cacagcagat actcctccgg caggtcgatt
    28021 aagcgacgcc ctttgtactt gccaaacggc attatcgtat tggctatttc aatcagctgc
    28081 tctttttcca tctcagctac ccagcaaacg cagcatttcc gtttcgtcga tgacttcaat
    28141 acccagttcc tgcgccttcg ccagtttaga tcctgcagct tcacccgcta tcaccagatc
    28201 ggttttcttc gacacgctgc ccgcgacttt cgcccccagt tcgaccagtc gagctttagc
    28261 gtcatcacgc gacatctggc ttaagctgcc cgtaagcacc acggttttac cagcaaacgg
    28321 actgtcaatc tcttccgcat tgataacgat cggctcaggc cagtgaacac cttccgccaa
    28381 cagctcgctg atgacattgc ggttgctttc ttcggcaaag aagttgtgaa cgtgggaggc
    28441 aacgacaatt ccaacatcag gcaccttttg cagctcttca atcgacgcgg cttccagcgc
    28501 ttccagcgtg ccgaaatatg ccgccagacc tgctgcggta gcctcgccga cttcacggat
    28561 gccaagtgca tagaggaagc gggcaaaggt ggtttctttc gctttttcca gcgcgttaac
    28621 cacgttttgt gccgatttcg gccccatacg ctccagtccg gtcagtttgc ctgcggtgag
    28681 tttgaacaga tccgccggag tgtggacata ttctttttca accagttgat cgatgatttt
    28741 gtcgcccatt ccgtcaacat ccatcgcacg gcgggaaaca aagtgtttca gagactcttt
    28801 acgctgcgca ccgcaaatca ggccaccggt acagcgggca accgcttcac cttccacacg
    28861 ctcgacgtca gaaccacata ccggacaatg cgtcgggaat acaacctcac gggtatcttc
    28921 cgggcgttca gaaagcacga cgttaaccac ctgcgggatc acgtcgccag cgcggcgaat
    28981 aaccacttta tcgccaatgc gtaaaccaag acgttcgatt tcgtcagcat tatgcagtgt
    29041 agcgttactc accaacacgc cagcaacatg gacaggttcc agacgcgcaa caggcgtaat
    29101 cgcgccagta cgcccaacct gaaactcgac gtcacgcaca aaggtcatct gttcctgcgc
    29161 cgggaattta aacgctaccg cccagcgcgg ggcacgcgcg acaaagccaa gctgctcctg
    29221 ctgtgccagt gagttgacct taatcaccac gccgtcgata tcaaagccca gcgtcggacg
    29281 gtctttttct actttgtgat aaaacgccag cacttcttcc gccgattcac aaagtgttac
    29341 ccgatcactg acaggtaatc cccatgcttt aaattgcatt aagcgtccca aatgggtatc
    29401 cggcaattca ccgccttcca gaacaccaac gccgtagcag aagaaagtga gcggtcgctt
    29461 cgctgtaata cgcggatcaa gctgacgcag tgaaccagct gccgcattac gtgggttagc
    29521 aaacactttc ccgcccgtgc gtcgcgcatc ttcgttaatc ttttcgaacc ccgcctgcgg
    29581 caggaacact tcaccacgca cttccagacg cgccgggata ttctcaccgt gtagcttcag
    29641 cggaatggcg cgaatagtac gcacattaga cgtgatatct tccccggtag tgccatcgcc
    29701 acgagtcgcg gcactgacta aaacgccatt ttcatacaga atactgacgg caagaccatc
    29761 cagcttcagc tcacagcacc aggtgacttt ctcgttgctt ttcagacggt cctgcacacg
    29821 tttgttgaaa gcaagaaagc tttcttcatc aaaaacgtta tccagcgaca gcattggcac
    29881 ttcatggcgg atctggctga aagccgccag cggcgctgca cctacacgtt gggtaggcga
    29941 atcaggcgta atcagttctg gatgtttggt ttccagctcg cgcagttcgc gcatcagcct
    30001 gtcgtattca gcgtcgggaa tttccggcgc atccatcaca tgataaagat attcatgatg
    30061 gcgaagcgtc gttcgcagtt ctgtcagttg ttgttcgatt gattccatat cgcaccatca
    30121 atgctaaaaa cccccgacaa gcgggggttc gaaaaggagt taatttgcct taagtgtatc
    30181 aggcgttggc gtctttgact tcgcggatga tgtcctggta ctcgcgcaat ttctgcggag
    30241 tcatcatacg gcgctgatcg tcaagcacta caccacccac ttcatcggca atatgctgcg
    30301 cagattgcag catcagcttg aagttctgca gctcgtcacc gtaagacggt acctgcataa
    30361 agatagtgac acccggagta gtgaaatcct tcatttcagg atcaaaggtt cccggtttca
    30421 ccatattcgc caggctgaat aacgccgggc cgctgccatc cgggctaaga tgacgatggt
    30481 aaatgttcat atcaccaaaa atgaagcccg cttgttgaat gctgttaaga agcagttcac
    30541 cgtttaactc gctaccgtga tgcgccgcga cgttcatgat aatcaccgct tctttgcgct
    30601 tcggtttatc cataactgga gccggttccg caacaggctc aggctgtggt gccgctacgg
    30661 gttctgcagg ctggaaagcc tgttgtgccg gttgcggtgc tgaatgcact ggctgcggcg
    30721 ctgacgcgac ctgtggcgaa actggctgct gcaacggctg ttcaggctgc ggctgatagg
    30781 caggctgctg cacgggttgc tgcaccggct gcgttggacg cggagcatgt tgcggcggta
    30841 cctgcgcttc aggcggctgc tggaccggtt gacgcggctg cgcagacgca taaggcggtt
    30901 ggtactggtg ttgcggcgac ggacgagcaa cctcatgctc ctgggcgtta gccggggcat
    30961 gattcacgcg gtgaacacga acctcaccaa cgccctcatc atcttcgaca tcctcgtcat
    31021 aagaatcgtc gtcacgtttt gacttcattc gttttaatgg ccgatcgcgg aacatagaag
    31081 atcgttcttt acggctggtc cagaaaccat gtaccagtaa agcgattatg gcgatcgcgc
    31141 caacaatgat taatatcaga cgcaaatcct gcatcattat attctctgtt gttctaacac
    31201 cttgccacca cggcaaacat ttactcacta agagtatttg ccgattacct caagtgcaag
    31261 tgcactatta actttcacag cacaaagata gatgaaatcg tgctttttgc tgttttttcg
    31321 aacatatcct aactgtccat tgcgcaatta cccggtaaaa tacgcagaat tttcctggga
    31381 ttggtcaaaa ggagctcatc ctgattatgg tttcatcatt cacatctgcc ccacgcagcg
    31441 gtttttacta ttttgcgcaa ggctggaagc tcgtctcgca acctgggatt cggcgtttcg
    31501 ttattttacc gctgctggtc aatattttgt tgatgggggg cgcattctgg tggctcttta
    31561 cgcaactcga tgtctggatc ccgactctca tgagttatgt tccggactgg ttacaatggc
    31621 tgagctatct gttgtggccc ctggctgtca tctctgtgct gttagtgttt ggctatttct
    31681 tctcaacgat tgctaactgg attgctgctc cgttcaacgg tttattggct gaacaactgg
    31741 aagcaagact gactggcgct acaccgccag ataccggaat tttcggtatc atgaaagatg
    31801 tgccgcgaat catgaaacgc gaatggcaaa aatttgcctg gtatctgccg cgcgcaattg
    31861 tattgctaat tctttacttc atccctggca ttgggcaaac cgtcgcgccg gtactgtggt
    31921 tcctgtttag cgcctggatg ttagccatcc agtattgtga ttaccccttc gataaccaca
    31981 aagtgccgtt taaagagatg cgcaccgccc tgcgcacacg caaaatcacc aatatgcagt
    32041 ttggtgcttt aaccagcctg tttacgatga tcccgctgct taatctgttc attatgcccg
    32101 ttgccgtttg tggcgcgacg gcgatgtggg ttgattgcta tcgcgataaa cacgccatgt
    32161 ggcggtaaca atctaccggt tattttgtaa accgtttgtg tgaaacaggg gtggcttatg
    32221 ccgcccctta ttccatcttg catgtcatta tttcccttct gcatatagat atgctaaatc
    32281 cttacttccg catattctct gagcgggtat gctacctgtt gtatcccaat ttcatacagt
    32341 taaggacagg ccatgagtaa gatttttgaa gataactcgc tgactatcgg tcacacgccg
    32401 ctggttcgcc tgaatcgcat cggtaacgga cgcattctgg cgaaggtgga atctcgtaac
    32461 cccagcttca gcgttaagtg ccgtatcggt gccaacatga tttgggatgc cgaaaagcgc
    32521 ggcgtgctga aaccaggcgt tgaactggtt gaaccaacca gcggtaatac cgggattgca
    32581 ctggcctatg tagctgccgc tcgcggttac aaacttaccc tgaccatgcc agaaaccatg
    32641 agtattgaac gccgcaagct gctgaaagcg ttaggtgcaa acctggtgct gaccgaaggt
    32701 gctaaaggca tgaaaggcgc aatccaaaaa gcagaagaaa ttgtcgccag caatccagag
    32761 aaatacctgc tgctgcaaca attcagcaat ccggcaaacc ctgaaattca tgaaaaaacc
    32821 accggtccgg agatctggga agataccgac ggtcaggttg atgtatttat tgctggcgtt
    32881 gggactggcg gtacgctgac tggcgtcagc cgctacatta aaggcaccaa aggcaagacc
    32941 gatcttatct ctgtcgccgt tgagccaacc gattctccag ttatcgccca ggcgctggca
    33001 ggtgaagaga ttaaacctgg tccgcataaa attcagggta ttggcgctgg ttttatcccg
    33061 gctaaccttg atctcaagct ggtcgacaaa gtcattggca tcaccaatga agaagccatt
    33121 tctaccgcac gtcgtctgat ggaagaagaa ggcattcttg ctggtatctc ttctggagca
    33181 gctgttgctg cggcgttgaa actacaagaa gatgaaagct ttaccaataa gaatattgtg
    33241 gttattctgc cgtcatcggg tgagcgttat ttaagcactg cattgtttgc cgatctcttc
    33301 actgagaaag aattgcaaca gtaatgccag cttgtaaaaa atgcgtaaaa aagcaccttt
    33361 ttaggtgctt ttttgtggcc tgcttcaaac tttcgcccct cctggcattg attcagcctg
    33421 tcggaactgg tatttaacca gactaattat tttgatgcgc gaaattaatc gttacaggaa
    33481 aagccaaagc tgaatcgatt ttatgatttg gttcaattct tcctttagcg gcataatgtt
    33541 taatgacgta cgaaacgtca gcggtcaaca cccgccagca atggactgta ttacgctctt
    33601 cgtgcgtcgc gtctgttaaa aactggcgct aacaatacag gctaaagtcg aaccgccagg
    33661 ctagacttta gttccacaac actaaaccta taagttgggg aaatacaatg ttccagcaag
    33721 aagttaccat taccgctccg aacggtctgc acacccgccc tgctgcccag tttgtaaaag
    33781 aagctaaggg cttcacttct gaaattactg tgacttccaa cggcaaaagc gccagcgcga
    33841 aaagcctgtt taaactgcag actctgggcc tgactcaagg taccgttgtg actatctccg
    33901 cagaaggcga agacgagcag aaagcggttg aacatctggt taaactgatg gcggaactcg
    33961 agtaatttcc cgggttcttt taaaaatcag tcacaagtaa ggtagggtta tgatttcagg
    34021 cattttagca tccccgggta tcgctttcgg taaagctctg cttctgaaag aagacgaaat
    34081 tatcattgac cggaaaaaaa tttctgccga ccaggttgat caggaagttg aacgttttct
    34141 gagcggtcgt gccaaggcat cagcccagct ggaaacgatc aaaacgaaag ctggtgaaac
    34201 gttcggtgaa gaaaaagaag ccatctttga agggcatatt atgctgctcg aagatgagga
    34261 gctggagcag gaaatcatag ccctgattaa agataagcac atgacagctg acgcagctgc
    34321 tcatgaagtt atcgaaggtc aggcttctgc cctggaagag ctggatgatg aatacctgaa
    34381 agaacgtgcg gctgacgtac gtgatatcgg taagcgcctg ctgcgcaaca tcctgggcct
    34441 gaagattatc gacctgagcg ccattcagga tgaagtcatt ctggttgccg ctgacctgac
    34501 gccgtccgaa accgcacagc tgaacctgaa gaaggtgctg ggtttcatca ccgacgcggg
    34561 tggccgtact tcccacacct ctatcatggc gcgttctctg gaactgcctg ctatcgtggg
    34621 taccggtagc gtcacctctc aggtgaaaaa tgacgactat ctgattctgg atgccgtaaa
    34681 taatcaggtt tacgtcaatc caaccaacga agttattgat aaaatgcgcg ctgttcagga
    34741 gcaagtggct tctgaaaaag cagagcttgc taaactgaaa gatctgccag ctattacgct
    34801 ggacggtcac caggtagaag tgtgcgctaa cattggtacg gttcgtgacg ttgaaggtgc
    34861 agagcgtaac ggcgctgaag gcgttggtct gtatcgtact gagttcctgt tcatggaccg
    34921 cgacgcgttg cccactgaag aagaacagtt tgctgcttac aaagcagtgg ctgaagcgtg
    34981 tggctcgcag gcggttatcg ttcgtaccat ggacatcggc ggcgacaaag agctgccata
    35041 catgaacttc ccgaaagaag agaacccgtt cctcggctgg cgcgctatcc gtatcgcgat
    35101 ggatcgtaaa gagatcctgc gcgatcagct ccgtgctatc ctgcgtgcct ctgctttcgg
    35161 taaattgcgc atcatgttcc cgatgatcat ctctgttgaa gaagtgcgtg cactgcgcaa
    35221 agagatcgaa atctacaaac aggaactgcg cgacgaaggt aaagcgtttg acgagtcaat
    35281 tgaaatcggc gtaatggtgg aaacaccggc tgccgcaaca attgcacgtc atttagccaa
    35341 agaagttgat ttctttagta tcggcaccaa tgatttaacg cagtacactc tggcagttga
    35401 ccgtggtaat gatatgattt cacaccttta ccagccaatg tcaccgtccg tgctgaactt
    35461 gatcaagcaa gttattgatg cttctcatgc tgaaggcaaa tggactggca tgtgtggtga
    35521 gcttgctggc gatgaacgtg ctacacttct gttgctgggg atgggtctgg acgaattctc
    35581 tatgagcgcc atttctatcc cgcgcattaa gaagattatc cgtaacacga acttcgaaga
    35641 tgcgaaggtg ttagcagagc aggctcttgc tcaaccgaca acggacgagt taatgacgct
    35701 ggttaacaag ttcattgaag aaaaaacaat ctgctaatcc acgagatgcg gcccaattta
    35761 ctgcttagga gaagatcatg ggtttgttcg ataaactgaa atctctggtt tccgacgaca
    35821 agaaggatac cggaactatt gagatcattg ctccgctctc tggcgagatc gtcaatatcg
    35881 aagacgtgcc ggatgtcgtt tttgcggaaa aaatcgttgg tgatggcatt gctatcaaac
    35941 caacgggtaa caaaatggtc gcgcctgtag acggcaccat tggtaaaatc tttgaaacca
    36001 accacgcgtt ctctatcgaa tctgatagcg gcgttgagct gttcgtccac ttcggtatcg
    36061 acaccgttga actgaaaggc gaaggcttca agcgtattgc tgaagaaggt cagcgcgtga
    36121 aagttggtga tactgtcatt gaatttgatc tgccgctgct ggaagagaaa gccaagtcta
    36181 ccctgactcc ggttgttatc tccaacatgg acgaaatcaa agaactgatc aaactgtccg
    36241 gtagcgtaac cgtaggtgaa accccggtta tccgcatcaa gaagtaattc ttgccgcagt
    36301 gaaaaatggc gcccatcggc gccatttttt tatgcttcag ccagaggcgg caaaatcaat
    36361 tcatcgctct catgctgctg ggtatagcgc atcacttcca gtacgcgcaa ccccgcgcgg
    36421 tgcaccgcat cggttaacgc cttccctttc agcaaaccac tgataagctg agcacaaaac
    36481 aggtcgccag tccctttcag gtcagtttta acccgggaat gggaaatgac attcacgctg
    36541 tcggcactga ccaccacaac ctgcatctcc tgattttctt cattgccgga ggcgctggta
    36601 atcaccaccc actttaatgt gtctgaaagc agactttttg cggcagcaat ggcactgtcg
    36661 agatcgcggc aatctttacc ggtcaggatt tccagctcaa agatattggg ggtaattccc
    36721 tgtgccagcg gcagtaaata ttgtcgatac gcctcgggaa ggtcaggttt gacataaatt
    36781 ccgctatcaa tatcgccaat caccggatcg accatgatca ataggtcagg atggtctttg
    36841 cgtagcgcag tcagccactc ggcaaggatt ttgatttgcg atgccgttcc catatagccc
    36901 gtggttacag cacgaagttg gcgcagcgca tcacgctcct gaagcgcacg caaataaccg
    36961 ctaaaccatt catccggaat cgcaccaccg tagaaagtgt cataatgcgg cgtattgctc
    37021 agcaataccg tcggcacggc aaagacattc aggccgttct gctttatagc aggcaccgca
    37081 atgctgttgc ctacgctgcc gtacactacc tgcgactgca cggcgacgat atccgcctgc
    37141 agtgccctgc tcttatcgtt aaacaacaac aaactactca tttaattttt tctccttgcc
    37201 gatgatcctc atcgtattcc agccgaaact ttacctgatt ctggcagtca aatcggctat
    37261 tacaaaacaa ggataaggta attcagtgaa gaaaatcatt tgtctggtcg ttacgctgct
    37321 aatgacactc cccgcttatg cgaagttaac ggcccatgaa gaagcccgta tcaacgccat
    37381 gctggaggga ttagcacaga aaaaggattt gatatttgtg cgcaacggtg atgaacatac
    37441 ctgcgatgaa gcggtttctc atctgcgcct gaagctgggc aatacccgta atcgcattga
    37501 tacagccgag cagtttattg acaaggtggc ctcgtcgtca tcgattaccg ggaagccgta
    37561 tatcgtgaag atgcccggta agagcgatga gaacgcacag ccttttttac atgcgttaat
    37621 tgcgcagacg gataaaacgg tgcctgcgca ataatcttaa atccccgccc cctggctaaa
    37681 atgctcttcc ccaaacaccc cggtagaaag gtagcgatcg ccacgatcgc agatgatcgc
    37741 caccaccacc gcgccagggt tagcttttgc cacccgcagt gctccggcaa ccgcgccgcc
    37801 ggagcttacg ccgcagaaaa tcccttcccg cactgccagt tcgcgcatgg tgttttccgc
    37861 atcgcgctga tgaatatcca gcacctcatc caccagagaa gcattgaaaa tccccggcag
    37921 atattccgca ggccagcggc gaatgccggg aatactgctg ccttcttccg gctgcaggcc
    37981 aacaatggtc accggtttgg attgttcgcg cataaagcgt gacacgccgg tgatagtgcc
    38041 ggttgttccc atgctggaga caaaatgggt aatacgcccg ccagtttgct gccagatttc
    38101 cggcccggta gtggtgtaat gggcgtaagg gttatcggga ttattgaact gatcgagcaa
    38161 ctttccttcg ccgcgattcg ccatctccag cgccagatcg cgtgcgcctt ccatgccctg
    38221 ttctttggtg accagaatca gttctgcacc gtaggcacgc atcgccgcac ggcgttcctg
    38281 gctcatgttg tcgggcatca gcaatttcat gcgatagcct ttaagcgccg caatcattgc
    38341 cagcgcaatg ccggtgttac cactggtggc ttcgatcagc acatcacccg gtttaatctc
    38401 gccgcgcttt tccgcctcga caatcatcga aagcgccgca cggtctttta ccgatcccgc
    38461 cgggttattg ccttccagtt ttaaccacac ttcactgccg ttatccggcg ccattcgctg
    38521 caacttcacc agaggcgtat tgcctattgt ttgttctaat gtactcacga tctctgtcca
    38581 tacgtggtgt tgcctgatgc gacgcttacg cgtcttatca gacctacagg ttacaaaacc
    38641 ttgccattaa aaaacccgga tcgcgggaag cgcctccggg cgtttaacat tcactcaacc
    38701 tatcaggcgc tttgtgcgag agcaagttcc tcatcgcggg tttcaatacg ctcatcgccg
    38761 ttatacagcc gcgcatgttg cagaccaacg tataaacgat cgccacgctg cggggcatcg
    38821 tcgccatgca tcacgaccgt cagcggttcg ttgtaccacc ccagcggctg caccactaat
    38881 tgggtgtagt gacctttcgg gctggcttcc agtacctgta cgggtagcgg cgaatcgagg
    38941 ctggtacggc ggctgatatc cacttcccac gggcgcagga agagatccac cggcccctga
    39001 tacgcggggg tgtatcccag cggccagcga tgtgcgccaa cgtggaactg cccgccgcga
    39061 atggttccct gcaggcggtt tacctcgccc ataaactcca gcacaaaacg agtcgccggt
    39121 tcacgccata cctgatccgg tgcgtcagct tgttcaatat tgccctgact catcaccact
    39181 acacgatcag ctacttcggt cgcctcttcc tggtcgtggg tcacgaacac gctggtgaat
    39241 ttcagttctt catgcagttg acgcagccag cgacgcagct ctttacgcac ctgcgcatcc
    39301 agcgcgccaa acggttcatc aagcagcaaa atttgcggtt ccacagccag cgcgcgtgca
    39361 agcgccacac gctgtttctg accgccggaa agctgcgccg gataacgatc cgccagatga
    39421 gcaagctgca ccatctccag caattttgtc actttcgctt tgatcgccgc cgcattcggg
    39481 cgttcacgcc gtggcaacac cgtcaggcca aaagcgatat tgtcaaacac cgtcatatgg
    39541 cgaaacagcg cgtaatgctg gaacacgaaa ccgactttac ggtcccgcgc gtgcagacgg
    39601 ctcacgtcgg taccgtgaaa gcgaatatgc ccactggttt gatgctccag cccggcgata
    39661 atgcgcagca gcgtagtttt tccggaaccg gacggcccaa gcaacgcgac catctgacca
    39721 gaaggaatat ccagtgagat atcgttcagc acctgggtgc gaccaaaaga cttcttaata
    39781 ttggcaatct caatgctcat gatgttcctc ctgctgcgcg cgtttttcct gattttccag
    39841 gcgccactgc aacatactct ttaaaaacag ggtgataatc gccatcagcg tcaacaacgc
    39901 ggcggcggta aaggagccga cggtgttgta gtcctgctcc agcaattcaa tctgtaacgg
    39961 cagcgacagg gtttcgccac gaatcgagcc ggaaaccacc gataccgcgc caaactcgcc
    40021 aatcgcgcgg gcgttggtca gcaccacgcc gtaaagcagc gcccagcgga tgttcggcag
    40081 cgtgacgcga cggaacatct gccagccgga cgcgccaagt aaaatcgccg cttcgtcttc
    40141 ctggctgccc tgacttaaca ttaccggtac cagttcgcgc accacaaacg gacacgtcac
    40201 gaagatggtg accagcacca tacccggcca ggagaacata atttgcagat tatgttcatc
    40261 cagccagccg cccagcgggc cgttagagcc gtagaacagc agatacacca gaccagcaac
    40321 caccggcgac acggcaaacg gaatgtccag cagcgtcagc aatagctggc gtccggggaa
    40381 gttaaagcgc gtcaccagcc aggccagcag aatgccgaac accaggttta ccggtacggc
    40441 aatcagcgcg atcatcaccg tcagccagat ggcgtgcagc atgtccggat cggccagatt
    40501 ttgtaacacc ggcatcagtc ctttgctgaa cgcctgtacg aagatataaa tcatcggcac
    40561 cagcaggatg aacgccgata ccagcatccc gatgccaatc agaaaccatt tgccccagtt
    40621 aatcgggcgc gcgtcataac gcttcaattg tgtcacttcc gccattaatg acctaccaca
    40681 cgccgaccaa agcgactttg cagagtgtta attgagaaca gcaacagcag cgatgccgcg
    40741 aggatcaccg aggcaatcgc gctcgccgcc gggtaatcaa actcctgtaa gcgaacaaag
    40801 atcatcagcg acgtcacttc tgttttccag gcgatattcc cggcgataaa aatcaccgcg
    40861 ccaaactcac cgaggctgcg ggtaaacgac agcgccacac ccgccaccag tgccggagat
    40921 agttccggca gcaccacttt gcgaaaactc tgccagcgtg ttgcgccgag cgtttctgcc
    40981 gcctcttcat attccgggcc taactcttcc agcaccggct gcacggtgcg caccacaaac
    41041 ggaatgctgg taaaggccat cgccaccgca atccccagcc aggtataggt gactttgata
    41101 tcaaacttcg ccagccattc accgtaaaaa ccgttcacgg aaaagagcga ggccagcgtt
    41161 aaaccggcga ctgccgttgg cagcgcaaag ggtaaatcca tcagcgcatc aagcagcgtg
    41221 cgacccggaa agcgatagcg ggttaagatc cacgccatca gcagaccgaa aacgccgtta
    41281 aaaatcgatg ccacaaacgc cgacagcagc gtcactttat aggctgcgac cacctgcggg
    41341 ttggtgatca cctcccagta ctgcgcccag ctcatctggg ccagttgcat caccagcgcg
    41401 gagagcggca gcagcaaaat caggcacaca aacagcagac tggtgccgag gcttaaggta
    41461 aagcccggca gcacgcgtct tgaagaaact gcaaacatta cttacgcccc gccgctaaca
    41521 gcttgtctaa ctcgccgccg ctggtgaagt gggttttcat cacttccggc caggagccaa
    41581 atttatcttc cacgcggaac agctcggtct gcgggaattt atctttcagt ttgcccatga
    41641 cttccgggtt atttacgcgg tagtaatagt cggtgatgat ggtttgcgcc tgcgggctgt
    41701 agagccagtt caggtaggct tttgccgctt tttccgtgcc gttggcctgt acgtttttat
    41761 ccacccacgc caccgggaat tccgccagaa tgttggtttt cggaatcacc acttcaaagc
    41821 cctgcgcttc atactgttta cggatgttgt tcacttccga ctcgaagctg atcagcacat
    41881 cgcccaggcc gcgctcggca aaagtggtgg tcgcgccacg accgccagta tcgaacactt
    41941 caacgttttt caggaactgg gtcataaact gttcggtttt ggctttatcg ccaccgtcgg
    42001 ctttatccgc tgcaccccac gcggctaaat aggtgtaacg cgcgttaccg gaggttttcg
    42061 ggttcggaaa aatcagcttc acgtcggagc gcaccagatc gttccagtcg tggatattct
    42121 tcgggttacc cttacgcacc aggaagccca tggtggagta gaacggcgag ctgttgtttg
    42181 gcagacgcga ctgccagtca gccggaataa gcttgccttt gtcgtgcagg atctgcacgt
    42241 ctgtcacctg gttataagtg acaacgtcgg cttttaagcc ctgcaaaatc gccagcgcct
    42301 gttttgatga cccggcatga gattgtttta tcgtcagttt gtcgccgccg ttatctttgg
    42361 cccattgctg ttcaaacggc gggttcaggg cggcaaacag ctcgcgcgag acgtcataag
    42421 aactgttcag cagttccgtt gcctgtacat ggcccgccag cagcagagaa gcgaccagca
    42481 cgagtgagtt ctttttcagt aagttaacgg ccattgcgca cccttataaa tttaatgact
    42541 ttctaatagc catcatattt ataacggacg tgaaaggagt aacggtttta tataccgttt
    42601 ggtgatttgg aagttgaaaa gggaataaga cgaaatcctc cccacaaatg cagggaggaa
    42661 acagaggtga atcagatgcc gacgctaacc gtctccggca gtgtgctgcc gccatcaatc
    42721 acattctgtg tacctgttaa atagctggat tcatccgatg cgaggaaggc cgccagttcg
    42781 ccgacttcca gcggatcggc gaggcgacgc atcgggattg ctttcgccat ttcagtcagc
    42841 accgattctg gatcttccgg gttcgactgg cgggcaatgc tttccgccat tggcgtgcga
    42901 acgtatccag ggcagatggc gttaacgcga ataccagact gcgcgtactc caccgccagc
    42961 gatttagtca ggccaacaat cgccgctttc gttaaggcgt acgccgtttc gcccgggtct
    43021 gccaccatat cgccagtgac tgaagacatc atcacaatgc ggccatcttt gcgggcaatc
    43081 atctccggca gcaccgcctt cgtgacgttc catacgcctt ttatattgat atcaatatgg
    43141 aaatcgcgat cttcatcgct catatcgagg aagctgccca gacgacaaac gcctgcgtta
    43201 ttcaccagaa tatcaatgcg tccttctttt tccttagcgc gcttaatagc tgcggctacc
    43261 gacgccgggt cacgcacatc ggcgacaacc gccgtacagc gatgaccacg accacacagt
    43321 tcgtccgcca gcttttcgat ctcaggggag atatccagca agattaggtt tgcgccatga
    43381 cgtgcaaaag ttctggcaat tccttcgcca attccctgca atgcgcccgt aatcagtgct
    43441 gtcttgcccg tgagtttacc cattttaatg ctctccttgt taatacagag cgttacactc
    43501 cattccctct gaaaatacag gataaacaaa atattgctgc ggatcagctc actaattcag
    43561 gaaaatctca atttagtcgc tgctttatgc agcacctcaa gcgttacgtc agcgcgcaat
    43621 cattttcagt gacatcacat gagtaatatt cggacttaat gattcctttg tgtctatcaa
    43681 atcgggatat atgatcccat ttatctgcaa ttatttgatc gcaaatatta aggtcaccac
    43741 cgatgcaact tgaaaagatg attaccgaag gctcgaacgc cgcctcggct gaaattgacc
    43801 gcgtatcaac gctggaaatg tgccggatta tcaacgatga agataaaacc gtaccactcg
    43861 ccgttgagcg cgtactgccg gatatcgccg cggcgatcga tgttatccac acccaggtaa
    43921 gcggcggcgg ccgtctgatt tatctcggtg cgggaacatc cggtcgtctg gggattctgg
    43981 atgccagcga atgtccgccg acctacggcg tgaaaccggg cctggtagtt ggtttgattg
    44041 ctggcggcga atatgccatt cagcacgcgg tggaaggcgc agaagatagc cgggaaggtg
    44101 gtgttaatga tctgaaaaat atcggcttaa ccgcgcagga tgtggtggtt ggtattgcgg
    44161 ccagcggacg cacgccgtat gtgattgccg ggctggaata cgcgcgccaa ctcggctgcc
    44221 gtacagtggg catttcctgt aatccgggga gtgccgtttc atccaccgca gagtttgcta
    44281 ttacgccggt agttggtgcc gaagttgtta ccggttcttc gcgaatgaaa gcaggcacgg
    44341 cgcagaaact ggtgctcaac atgctctcta ccgggctgat gattaaatcc ggcaaagtgt
    44401 tcggcaacct gatggtcgat gtggtcgcca ccaacgaaaa actgcatgtg cgccaggtca
    44461 atatcgtcaa aaacgctacc ggatgtaatg ccgaacaagc ggaagcggcg ttaattgctt
    44521 gcgagcgcaa ctgtaaaacg gccatagtga tggtactgaa aaatctcgat gccgctgaag
    44581 ctaaaaaatg cctggatcaa cacggcggtt ttattcgcaa ggctctggaa aaggaataac
    44641 ccatggctaa agagatcagc agtgaacttc taaacaccat tcttacccgg gtcggcggac
    44701 cgggaaatat cgccagttgt ggtaactgta tgacgcgcct gcgtctgggt gtacatgaca
    44761 gttcactggt tgatcccaat atcaaaacgc tggaaggcgt gaagggggtc attttgacca
    44821 gcgatcaggt gcaggtggtt tttgggccag gcaaagcgca tcgtgccgca aaagccatga
    44881 gcgagctgct gggcgaggca ccggtacagg atgccgcaga aatcgccgcc cagaataaac
    44941 gccagttaaa agccagacaa acttccggcg tgcaacaatt tctcgccaaa ttcgccacca
    45001 tcttcacgcc gctgatcccc ggttttattg ccgccggtct gctgctgggg atagcgacgt
    45061 taattgccac ggtgatgcac gttccggcag atgctcaggg cacgctaccc gatgcgctga
    45121 attttatgaa ggtgttcagc aaaggcctgt tcaccttcct ggtaattctg gtgggctata
    45181 acgcggccca ggcatttggt ggcacgggcg taaatggcgc aattatcgct gcgctctttt
    45241 tgctcggtta taaccccgct gcaaccacgg gttactacgc cggatttcac gatttctttg
    45301 gtctgcctat cgatccgcgc ggcaatatta tcggcgtgtt gattgccgca tgggcctgcg
    45361 cccgcatcga atgcatggtg cgccgcttta tgccggacga cctcgacatg ctgttgacct
    45421 cattaatcac cctgctgatc accgctacgc ttgcgtacct gatcattatg ccgctgggcg
    45481 gctggctgtt tgaaggtatg tcatggctgt ttatgcacct gaacagtaat ccgctcggtt
    45541 gtgcggtttt agccgggctg ttcctgatcg ccgtggtatt tggcgtgcat cagggcttta
    45601 ttcctgttta tctggcgtta atggacagcc agggattcaa cagcttattt cccatccttt
    45661 caatggcagg cgcaggccag gtgggcgcgg cgctggcgct ctactggcgg gcgcaaccgc
    45721 acagtgcatt acgcagtcag gtccgcgggg cgattattcc cggtctgctt ggcgttggcg
    45781 aaccgctgat ttacggtgtc accctgcccc gcatgaaacc gtttgttacc gcctgtttag
    45841 gcggcgcggc gggcggtttg tttatcggcc tgatagcctg gtggggtctg ccgatgggct
    45901 taaacagcgc cttcgggccg tctggtctgg tggcgctgcc gctgatgact tccgcacaag
    45961 gcatccttcc ggcaatggcg gtttacgctg gcggtattct ggtggcatgg gttagtgggt
    46021 ttattttcac cacactcttt ggctgccgta acgtcaatct ggactgatta tgaaacggac
    46081 aatgctctat ctttctctgc tggctattag ctgtagcgtc agcgccgcaa aataccctgt
    46141 tttggcagaa agtagttgat caagtgtatg cggcgtcaaa gcagtaataa aaaggccagt
    46201 cagttgtgtt actggctggc ctttaatcaa tgaatcagaa acgcttacag cgccatcagc
    46261 ttgtccagcg acggtgcgaa gtaatagccg ccagtgaccg gtttggtgaa acgcaacatc
    46321 gcatcacgct taccatcggt atcgccaaac atgctcagca gttgctgctc aatgttatgc
    46381 agacgcgcgc agtaggcgca gaagtacaga ccgtgagtgc cactggcggt gccgtacggc
    46441 aggctctgac gaacaatctt cagccctttg ccatcttctt tcagatcaac gcgggtcagg
    46501 tgagaggttt ccggacgttc gtcgccgtca atctcttcgt tggcctcttt ggtgcgccca
    46561 atcatcatct cttgatcgtg aacgctcatc cgattgagct gcttcaggtt gtgctcccaa
    46621 cgctgcacaa acacatagct gccgcccgca tccacgccgt ctttgataac agccacttcg
    46681 cggcgcgtct cttcacccgc cgggttttct gtaccgtcaa caaagccgct caggtcacgc
    46741 tcttcaaccc aacggaagcc atggatctct tctttcactt caatgcagtc accaaaggct
    46801 tccatcgccg cctgagcgac agagaagttc acgtcgtgac gcagagaaag aatgtggatc
    46861 aacacatcga actgggtcgt cggtgcaaga cctttaccgt agcccggaaa atctttcagc
    46921 tcttcggccc caacgccgcc gctcagagcg cgccaggtat tgttaccaaa ggcaaccacc
    46981 gcaccaagat gcgcgtccgg gaatttcgct tcaaaagttg ccagtttgtc ggcaaatgtt
    47041 ttactggccg cacgcagggc gtcaacttcc cctttcacgt tggcttcgat ccaaatcgcc
    47101 gcgcggcaat gttctggcaa aatgccactc tgaacctgag acattgttcc tcctgaaaat
    47161 aataatgcca cgcaatccgt ggcattgttg ggcgctattt tacgtgtttt ttcgcggcgg
    47221 cggtttgttc agacgcaaat taacgccgcc agataatttt actgactttc cagtttttca
    47281 gggtatcgtc cgaaggcatt aacccttcag gaccactcca ttccccgctg aactggtagc
    47341 taatatgttg actgccttcg gctttacatt cgacggcacg attatcatca ctgtcggcct
    47401 tttggcaatt gccaaatgct ttgctgtaaa ggtcactaaa cggtgtaccg attttaacac
    47461 cggtgtcagc aggaatatcg ctatccagca catcaatgcg gctgatcgtg ccttgatcgc
    47521 cgttaatcac catcgccacg ttgttgcctt tcatcacttc aaaaaagcgc accacgttgc
    47581 cgttcgcggt tttcattccg ctgcgcaggc gataatcgcc atcaagcgca tcagcaatgg
    47641 cttgttcttg cagtggtgtg gacgccgtta attcacccac gccctgctcg ctcactttgg
    47701 tggatgatcc aaaccagttc cacgggttag cggccgacca gttaactgac gacatcgtgg
    47761 aacagccggt cagcatcaac ggcatagcgc ataacattaa acgcagcgat ttcatgtcac
    47821 ttcctttggt tattcaataa cgttgcttgg agtgcaaatt caccaaaaag tgccgttatt
    47881 ctttttcttc attaaaacaa gcgcgtaaac gtcgattggt cagcagccag attaacgcca
    47941 cgatatccgc cactaccagc gccagaccga taccgctaac ggattcaccg ttcagccaca
    48001 gccacggttg ccaacaaagt aaaaccactt gcgccaacag caacagaaaa tagagcacat
    48061 gccagatacg gggaaatgaa gcccgccgac cactcagcaa aaatgccagc accgccggaa
    48121 taccgggaat caaccccagc cagaaattat cgtgatcggg ataaaacaga tttagcagcg
    48181 cagtaccctg ctcgcgcgac gctccggcaa tgacaaacag cacccaggtt cgcgcctgaa
    48241 gcaatagcac aagccagaag agcaagggta aacgcaggcg accgtgcgca tcataatgga
    48301 caggatgaaa ctcagtactc ttcatcttca atcaaacgct tacccagact cagcacgtcg
    48361 gcgtgttcat atcccaggcg ttcatacatt ccgagcacca tgtcgttatc ttccggcacg
    48421 ttgatctgaa ttttcggaca gccgcgagca atcagctttt tctccagccg attaagcaac
    48481 gcattagcaa tcccacgccc acgaaactcg ggatgcacgc caagataata agcagacccg
    48541 cgatgcccgt cataaccgcc catcaccgtt ccgaccactt caccgttcac ctcagcgacc
    48601 agaaacaaac tgacgtcatg gttcatctta cgctcgatgt ccatttccgg atcgttccac
    48661 ggactcagca agtcgcaacg ctcccaaagg gtgatgacct cttcgaaatc ttcctggcga
    48721 aatacgcgta tctccatggt attcgttacc tttttgcggg ttaaaaggct gattatggcg
    48781 tgaacggtcg aattagccaa tatctgacga aaatcggttg aaaaagtggc ataatgggga
    48841 gttgtcaact attgaaatga aaagtaaaac aattctcaac agcaaaccgt cgtaacggat
    48901 tacgcgatac gatataacat ctggaacttt attattacaa ctcaggccgt atgagcactt
    48961 ttaaaccact aaaaacactc acttcgcgcc gccaggtgct gaaagccggt ttggctgccc
    49021 tgacgttgtc aggaatgtcg caagccatcg ccaaagaaga accgttaaaa accagtaacg
    49081 gacacagcaa gccgaaagca aaaaaaagcg gcggcagacg tgtcgttgtt ctcgatccag
    49141 gccacggcgg gattgatacc ggagcgatcg gacgcaacgg ttcgaaagaa aaacatgtgg
    49201 tgctggcaat tgccaagaat gtccgttcca tattgcgtaa tcatggcatt gatgcgcgtt
    49261 taacgcgttc tggcgatacg tttatcccac tgtacgatcg cgttgaaatc gcccataaac
    49321 atggcgcaga tctgtttatg tcaattcatg ccgacggctt taccaacccg aaagctgccg
    49381 gtgcttcggt atttgccctc tctaaccgcg gggcaagtag cgcaatggca aaatacctgt
    49441 ctgaacgcga aaaccgcgcc gatgaagttg ccggtaaaaa agcgactgac aaggatcacc
    49501 tattgcagca agtgctgttt gatctggtgc aaaccgatac tattaaaaac agcctgacgc
    49561 tcggctcgca tattctgaaa aagattaagc cggtgcataa actgcacagc cgcaacaccg
    49621 aacaagccgc gtttgtggtg ttgaaatcgc cgtcggttcc gtcggtgctg gtggaaacct
    49681 cgtttatcac caacccggaa gaagagcggc tgttaggcac ggcggcgttt cgccagaaaa
    49741 tcgccacagc gattgccgaa ggcgtgatca gttatttcca ctggtttgac aaccagaaag
    49801 cacactcgag aaagcggtaa gtgatgaaac ccgacgcaca cctggttaaa cagttcttgc
    49861 tcaaccttca ggatacaatt tgtcaacaac tgaccgccgt cgatggcgca gagtttgtcg
    49921 aagatagctg gcaacgtgaa gctggcggcg gtgggcgtag tcgggtgttg cgtaatggtg
    49981 gtgttttcga acaagcgggc gtcaactttt cacatgttca cggtgaggcg atgcctgctt
    50041 ccgccaccgc tcatcgtccg gaacttgccg ggcgcagttt cgaggcgatg ggcgtttcac
    50101 tggtagtgca tccgcataat ccgtatgttc ccaccagcca cgcgaatgtg cgctttttta
    50161 ttgccgaaaa accgggtgca gagcccgtct ggtggtttgg cggcggcttc gatttaaccc
    50221 ctttctatgg ttttgaagaa gacgccattc actggcaccg caccgcccgt gacctgtgcc
    50281 tgccatttgg cgaagacgtt tatccgcgtt acaaaaaatg gtgcgacgaa tacttctacc
    50341 tcaaacatcg caacgaacag cgcggcattg gcgggctgtt ctttgatgat ctgaacacgc
    50401 cagatttcga ccactgtttt gcctttatgc aggcggtagg caaaggctac accgacgctt
    50461 atttaccaat tgtagagcga cggaaagcga tggcctacgg cgagcgcgag cgcaattttc
    50521 agctctaccg tcgcggtcgt tatgtcgagt tcaatctggt ctgggatcgc ggcacgctgt
    50581 ttggcctgca aactggcggg cgcaccgagt cgatcctgat gtcaatgccg ccactggtac
    50641 gctgggagta tgattatcag ccaaaagacg gcagcccgga agcggcttta agtgagttta
    50701 ttaaggtcag agattgggtg taactccctc acccccactc tcgcatccgc tgatgcagcg
    50761 tcagtgacgg cttctcggca aacagttgct gataatccgt ggcaaattgc ccaagatgcc
    50821 agaatcccca ctgcatggcg gcgtctttta ccgttgtgct ttgtgaccac ggacttatga
    50881 gttcgcggcg cacggcgttc aggcgaatac gtttcagcca cgcgttcgga ccaatgccca
    50941 aaatggcgtg aaatgcgttt tgtagcgtgc ggcggctgac atgcagttga ttacacaagt
    51001 ccagcaccgt caccggttcg gacatgtttt ccagcacata ttcacgggcg cgggaaagca
    51061 atcggcggta actctgatgg ctgatgcttt ccgccgtcat catcggctgc gcttcttcca
    51121 gcatcgcccc catcgccatg agcaaattat cccccagcac ttttcgcact gcaggctgat
    51181 ggagattttc cgggttctcg caaaacgtcg ccagcgcctg ttggacaaag ccccacagag
    51241 cggctttatg ctgctctttc acttccagcg ccgactggct acgcagcata tgtaataccc
    51301 gatccggatt atgcaaaaag ttagcctgac gagtgatgac atcttcagaa agcactacgc
    51361 caaggatcgt gtaatcgtcc ggcgtactta attcaaactc ggttccaccc gggcgcgtcg
    51421 caatttctgc gcttcccaga cattgcgaac cgataaatcc cagctcaccg cgcgtcgccg
    51481 gaatgccaaa ccagaacgag ttcggccaga ccaggcacga ctgacgcagc gccagaccag
    51541 tgtattcacg aaaaacctga atatcatcga gtagaatttc cgtaaattca ccatgaaact
    51601 tgcccggatg cagctgatcg taaatctgct gccaggcggt aattgtcaaa gcatgttcat
    51661 agacgtccgt tgtctgtcgt tgatgaacat tatccacttc gaccttcggc gtgagcttca
    51721 ggttttcggg taagggttca tgataaagat ggtgcaaatt ggctgtacgg gtctttttca
    51781 tgatgttaat gccgggtgtt gtaggacacc cggcacctcc gacaggttaa tggggcttga
    51841 gacggtaacg actactgcgt ttacgtaacg tcccggcaga aaagagctgt tcgagcgcat
    51901 ttctggcttt ttccagcggc cagccaaagt gggcagccac ttctcctgcc gtcattccct
    51961 gacgtactga tgttaacagc gccaacaact cgtcagcaga ttccgcgacg ataactggcg
    52021 cgtcgggttc ctttacgggt tgcttaggct ggcggttaaa gccagtaacc agccactggg
    52081 tgtcatcgtc tggccgaccg atctccttgc ggctgatgac acgcccggta cgcatcgcgg
    52141 cagcacaacc tgcgtccagc gccgcacgac acgccgccag atcgccttcc accaccagcg
    52201 ttaggcgacc agggtcaagc acttcgtgac tgagcagacg aacgttagct gctttgagca
    52261 tggcatcagc tgcatctatc gcggcgacca tgccgtccac ttccagcaat cccagtgcat
    52321 tgatcatcgg caacctccgt tacgcacgct ggattggatt acgcgcgatt tccagcactg
    52381 catcggtaaa ggcgttacag gctgctttac acgcggcctg gctaccggtt aaaaatgctg
    52441 ccgagtagtt ggtttcagac ggtggcggga cataggtcac cagctgcacg tcggcagatt
    52501 tcaacgctgc atcaatgccg taggtcgctt ccagcggcgg tgccaccaga tacgccatcg
    52561 gatcgccaag cgtgatcccg gcggttgatg agagataaga accggtacgc gaaactacat
    52621 gtgccaggaa ggctgtgttt tctgcgtcat tagcccactg gaaagcagcg ccattttcaa
    52681 tattcgcaac catcgcatcc agaccagcac gcacttccgc cgggtttggt ccaccaagca
    52741 taatcagcac ctcaccggca gtcggtgacg ggccgtgtgc agcgcccgca tacagcgagc
    52801 gaccatatac cacttcgacc atcgcctgct tggtcgcttc gtcagccgca atgtaggtga
    52861 cgtcatctga atcagcagaa atcagcccga ggctacgaat atgcggcggc aatttcagtt
    52921 cacgtgcaaa ttcggcgtta acggaggcaa tcacccgcat ggcggttacc gacggtcgaa
    52981 tcaaatctaa agctggcatg atgcctcctt atcgggtcat gttgatgccg gatgctttct
    53041 gctccagcat acgtttcgcc aaatccacaa tgacggctgc ggcttcaacc ggcggcgtgc
    53101 cgccctggtg aatgttagag atacaagtgc ggtcagcctc aacggtggtc gccatacgcg
    53161 gcgagtaaac ggcgtagcag gagaggcttt ctgactgccc caaccccgga cgttcgccca
    53221 ccagcaggat cactactttc gcgccgagga tctcaccgat ctgatcttca atcttcacgc
    53281 gaccataacg tacaaagaat ggcgtaccga ctttcagccc ggcttgcttc aggcccgcca
    53341 tcagcggcgg caggatctct tcgtagttca cggtgatcgc atcagttgac aggccatcag
    53401 aaataacgac ctgcacgtcc ggattagcaa cacactgtgc tttcagcgct tcaacagctt
    53461 ctgcacacag gcggcggccc atatccgggc gagtcaggta gagatttttg tcgctgattt
    53521 cggagcggac ttccagcaag ccctgcgctt tcacccactc ttccggtact tctttcagaa
    53581 cggtatcttt cgaacgagag tgatcggcca ggaaacgcag caacgcctgg gtgcgcggac
    53641 gcggaccggc acgaccggta caaacgcggg ccacggtgct gcgacgcagt tctgttaata
    53701 cgtctgcgtg atgcgggttt tcaacaccaa tccacgcttt tgcttccgca gaacctaaat
    53761 ccagcgcgca gctttccgag gtcaccggtg ccgcacaggt ggtggtggcg cactttgctt
    53821 ctgacggcgc gggggccgct tgtcccattg acgccatcac gctgcgtaca atttcttcaa
    53881 tctgtttttg atccatgatg tgttatctcc gcgtcatcag aagaacagtg acggatcgcc
    53941 cgcccgtttg gtcaggcgac cgtttgccat aatgcccatg ctttccagcc agcgttcaaa
    54001 ctccggtgac gggcgcagat tcagtaactg acgcacagtg gcagtgtcgt ggaatgcggt
    54061 ggtctgatag ttgagcatga tgtcatcgcc cagcggcatc cccatgatgt agttgcagcc
    54121 tgcggtggcg agcaggatca tcaggttttc gttgaggttc tggtcagcgt cagcgtggtt
    54181 ggtgtagcag cagtcacagc ccatagagat gccgctcagt ttgcccataa agtgatcttc
    54241 taagcctgcg cggataatct ggcggtcgtt gtagagatac tccggcccaa taaagccgac
    54301 cacagtgttg acgataaacg gatcgtaatg acgcgccagc ccatagttac gcgcttccat
    54361 cgtcacctgg tctgcgccga agttcgcgcc agcagacagc gccgaacctt gtccggtttc
    54421 gaagtagagg cagttttccc cggcgatacg gttgaactcc gcgcccactg cgcgtgcttc
    54481 atcgagcatc gccagctcta cgccaaactc tttcagccct ttttcgctgc cgcagatact
    54541 ctggaaaatc agcccgcctg gtgcgccgcg acgaatcgct tcgatttggg tagtgacgtg
    54601 cgccagtatg cagccctgag ttgggatgtt gaatttgtcg atcacgccat agatggtatc
    54661 caacacgcgg cttaagtttt ccacgtcgtc agtcaccggg ttaacgccga tcaccgcatc
    54721 gcccaccccg aaggaaagcc cttcgtagat ttgcgcggcg atactttgca cgtcgtcacg
    54781 ggtatcgttc ggctgcaagc gggcgctgaa ggtgcccgga ataccgatgg tggtattggc
    54841 ctttttgatc accggcattt tcttcgcgcc gtagatcagg tccgcgttgg agcaaatctt
    54901 cgctaccgcc gccaccactt ccgaggtcag ccctttgcgg gtaaaggcaa tgtcatccac
    54961 gctggtttca tcgctcagca catactcacg cagttcgctg atgctccagt ttttaatctg
    55021 gttgtaggcc gtttcgttaa cgtcgtcctg aatcagccgc gtcacgcagt catcttcata
    55081 ggcaatcacc ggattattgc ggatgtccgc tacagtcatt tccgacaaca cctgctttgc
    55141 cgccacgcgc tcctgtgagc ttgccgcagc aacgcccgcc agcacatccc ccgaacgcag
    55201 ttcgttggct ttagccagca cctcttttac atccttaaac tgatatacat tgccgaacaa
    55261 tgtggtcttt agtttcataa gtcgttccct caggaaggaa atgcgagtga tttcaccgtc
    55321 accggcacaa ccgatccgcc aaaaagaggc gtaccaatgt cgatatagtc ccccgcgcgg
    55381 acaatcactt cgtcaatgac tgccaacggg agttgttgta gctgtgggcg caacaacatg
    55441 cccagagctt taccaaagtc ctgcccggcc accaccagca ggggatgcgg attcggaaaa
    55501 cgcgcgacga aatcgaccag cgcgttgatg accgtcagta ccgcggcgta acgcacaggc
    55561 agcgaggcgg gaagcgccag cacgtacgcg tcagttttgg ggcaaagatc cagttgaatc
    55621 agcgcctgtt gccaggcact gaccagatcc gtttcatcaa tcgggatcgc caccggcaaa
    55681 ttgcgcagcg gcagttgtac gccctccagc catattgtgc tgccagagag cgaaagggta
    55741 tgtgcacccg cgccaatcac cgtggcgcgc acggtttgcg ccggaaactg cacgttcatc
    55801 tcacgcagac gcggatggtc atgcagcgcc gttgccagaa gcgggccgat atcggcaaaa
    55861 cagaacgggt cggcgggctg gtggcgataa cattcgccta ccccgccaga aagcgtaatg
    55921 atttcgggcg taacacctgc gggcagcaaa ccggtttgca tcaatgcctg cgcgagcggc
    55981 gagagcgttc cgtcaatcac ttcgacaatc agttccgcca tccggcgggt aacctgcgcc
    56041 aattgcgcgc cggtcagcga acgggcgtca gtgcctgggc cgaagcactc atccacaatc
    56101 atctgccccg gtttatgagc gtaaaccacg cgcccctggc tgtcggtttc cagcaggcga
    56161 ccgccgacgt tgaggcaggc agtgccgctg atttttccgg catcgaacag ggcgtagttc
    56221 gcggtgccac cgccgatgtc gatattcagt acccgacaca gccgttgttc agaaagggtt
    56281 tgcgccccgg caccgtgacc ggcgatcacg gattcgagat gcggcccggc gctggcgacg
    56341 acaaaatcgc ccagcgaccg agagagcgcc atcaccgccg ggcgagcgtt gcgggttttc
    56401 gcgctttcac cggtgatgat gatggcacca gaatcaacgc tttccggcgc aatgcccgca
    56461 gcctgatatt gctcgaggat taaggttttc agttccgctt cttttaaacc accctgttta
    56521 tcgacagggg taaagaacac cgggctttgc cagctaattt cgcgtttgat gaattcgtag
    56581 cgcggcacct gcgacaccgc cgcacggtta accagctcca ggtgggagaa gatcacctgg
    56641 gtggtggtgg tgccgatatc gataccgacg ctcagtagct ggcgagtgtt cacgattgcg
    56701 cctccgcttc ggttttagcc gcgctcgcgt cttcttttgg caccagcatc atcgccacgc
    56761 caattgccgt tacgccgccg atcaatttgc cgacaatcat cgggaagatc atggcgttca
    56821 tgttggcagc ggcgaagcct aaatggtcgc ccagcgcgaa agcagcggaa acggcgaagg
    56881 cacagttgat gactttgccg cgggtatcca tctgcttcat catgccaaac atcggaatgt
    56941 tgttggcaag cgttgccacc atgccggctg ccgcgatatt gttcatattc agcaccttac
    57001 cgacgctcat cagcggtttt tcaaaccagc gagtcagcag cagtaccatt ggatacgccc
    57061 ctaacagaac gcaggagatc gagccgataa cttcaatggc gcgcatcact tcaccgggtt
    57121 tatcgccagg ggccataaag ataggatcaa ggcccgggat cagttcccag ccaaggagga
    57181 atttcactac cgcagcggca agaccgaggg tgatcaatgc aacgaggaat ttggcgaaga
    57241 tctggaagcc gttgatcatt ttttccggga tgaatttcag ccccagcgcc accagcaccg
    57301 caacgataag taccgggatc atgttcatca ggatcagcgc aaaggtgaat tcaacaggct
    57361 ggccgttgat ctgcacaccg gagtacatcg ctaccagacc accagcgata cagccaatcg
    57421 gaatggtcac tatgcccgcc agcacgccga gcgccagata acgacggtca gaaggttcga
    57481 taatgccgag cgccaccgga atggaaaaca caatcgttgg ccccatcatc gacccgagaa
    57541 ttaacccaga gtatagccac gctgctacgt caccgcccgc cagctctttg gcgaggaaga
    57601 agccgcccat atcgcacgcc agcagtgttc cggcgaacat tgacgggttt gcgccgagca
    57661 tttcgtaaac cgggataatc accggtccga gaacgtgggc cagtaccggt gccagtgcgg
    57721 tcataccgac catagccagg cccagagcgc ccattgccat aaagccttct tcgaactgac
    57781 cgccggatcc ttcgatactt ttaccgaact taccgaggaa acgagcagaa ccgccgaact
    57841 gcgacaggat cctgtctacg gcagctatca gcataaagaa catcatgatg tacatgatga
    57901 tttcgttaat tcccatcgcc tttactccct gttagttgtt atttattggc ggatgcggcg
    57961 tgaacgcctt atccgcccta catgtgcaat cccgaaggcc agataagacg cggcaagcgt
    58021 cgcatccggc aattgcaccg cgccactggc ggatgcggcg tgaacgcctt atccgcccta
    58081 catgtgcaat cccgtaggcc ggataagacg cggcaagcgt cgcatccggc atttattgcg
    58141 ccgctgcgta caggccgaca atctgctcga ggctggcggt acgcgggtta ctgcgcagac
    58201 aaatatcttc ctgcgcggcc tgcgcccatg caccgtaatg cccggttgtt gcacccacat
    58261 cagccagccg cttgttgatc ccaacttccg ctatcagctc acttaccgca ttaatagcgt
    58321 cacgatcgtc ggatttttta gttcgcagcg cccgaccaat ctgactaaac cgatcacgac
    58381 aaaccatccg gttaaattcc atcaccgttg gcagcaacat ggcgttcgcc agaccgtgcg
    58441 gaatatgcag cgccgcccct ggctgatgcg ccatcgcgtg gcataaccca agcccggcgc
    58501 tggaaaacgc cattcccgcc atacatgaag ccagcaacat gctctcgcgg gcgacaaggt
    58561 cgtgaccgta gcccaccgct ttcggcagcg attgaccaat catcgcaatg gcgccaatcg
    58621 ccaggctgtc ggtaaacggt gtagcgttca gcgcgctgta cgcttcaatg gcatgggtta
    58681 acgcatcaat gccagtcatc gccgtgacat gcgacggcac gccttcggtt agcacagcgt
    58741 cgagaatcgc gacatccggc atcagcgagg catgggctaa cacctgtttg cgcccgctta
    58801 ccgcatcgat aatcaccgtc acgttggtgg tttcagagcc ggttccggcg gtcgttggaa
    58861 tggcaatcaa cggcaggcgc ggttgcagaa cgctggtttc tgacatttct gccagcgtgc
    58921 tatccgggtt cgtcaccagc aacgccacgg ctttcgccgc atccagcacc gagccgccgc
    58981 caaacgcgat caccccgtca caacctgatt cacgcaactg cgccacggct gcacacacgt
    59041 cggtgatgca cggttcgccc accggacatg gccagagcgt catggcgata cctttaacgg
    59101 ccaggctacg cgtcagccca gcggtcatcc ctgcctgatg caaaaagctg tctgccatca
    59161 cgaacagatg tttcaaccca cgcgtttgcg cttgctgccc acaactgctc accgcgcccg
    59221 gaccgcaaag cgtcaccggt ggaacgctaa atgtttttac ccgttgcaga ttcagggtat
    59281 cgaacgcctg aaagagcgcg gtctgcaatt cattttgcat atagcccctc cgctttctct
    59341 cgcccactac tggcgattgc cagcggggtc ataaacaaac tgtgctgcgg taaatgcacc
    59401 tgtaacgccg gaaattgttt gcaaaacagc gccgctacgc ccggttgcat acaggaaccg
    59461 cccgccagcc ataaatccgt aatgccctgc ccttcaatat gacgggccac aatgtccgcc
    59521 attttttcgt acaccggttt caccgcgggc caaatctcgt caccgtgacc gcgtttgtac
    59581 tgctctgcct cttccagcga aatacggcga tttccggcga gagtcagaga gatgtgatgt
    59641 ccgccggtgg cttcatccgc cgagtacgtc actttgccct ttttcacgat ggcaatgccg
    59701 gtagtgccgc cgccgatatc cactacaccg gcgttgtcca gttgcagcag atccgcaact
    59761 gcggttggct catccagcac atggctcact tccagtccgg cagactccag cacgttgatg
    59821 gaaatacgcg ggtccgtacc aggaggaaat gaggtcgccg catggctaaa acggcgaccg
    59881 aattgctgct caagggtgtc gagatggcga cgaacaatgg tgaccgcacc gaagaaatcc
    59941 cagacgatgc cgtcgcggac cacatcggcc cagtcgaggc ataccgccac cggctgaccg
    60001 tcgcggtcga caaccatcga caccacatcg caggtgccca gatccacccc cagccacagc
    60061 ggagattccg tcgcggcggg cgtctggtta cacagcgttg ccgccgtttg cagacgtggg
    60121 gtgagccatt gttcatcgtg cgccatcggt tactccttaa acaatgcgaa acgcatcgac
    60181 taatacacag cgacgcagac ggacaaacgt ccgcgcgctg gttacccctt caccggttgg
    60241 cgtggtgatg gtcatcgtgg tccagccttc cccgcccagc cccagcccgg caatacacgg
    60301 tccgttctta acgaaaatgc tggtatcaat ggcgttcgcc atctggttca tgttttcgat
    60361 attgcgcgag tgcattgccg ccgtgtggtg gcaaccgcct tccagtttca ccgccagcgc
    60421 aatggcatcc gccacgttgg cgacgcgcac gacgggcagc accggcatca tcagttcggt
    60481 cacggcaaac ggatgttctg cggtggtttc tacaaacagc agtcgcgttt gttccggaac
    60541 tttaaggccg attgccgccg cgattttcgc cgcatcgcga ccaacccagt cacggctgac
    60601 ggtgcctttt ccgcgctcgt cgatattttt cagcaacacc gattgcagtt gctgcgcctg
    60661 ctctgcggtc agtttcaccg catgctggcc ttccatcaga cgcatcagtt catcggctac
    60721 gctatcaaca acaatcagta ccttttcgtc ggcacaaatg atgttgttat cgaaagaagc
    60781 gcctttgacg atggactgag cagcacgggc gaggtcggcg gtttcatcca ccactaccgg
    60841 cgggttgcca gcgcctgcgg caatcagacg tttattggtg tgtttacgcg ccgcttctac
    60901 taccgcttcg ccgccggtca ccaccaaaag gccgatgccc ggaaacttga acaagcgttg
    60961 cgcggtttcg atatccggat ttgttacggt aaccagtaag ttttccggcc cgcctgcggc
    61021 aacaatcgcc aggttgagca gcgtaatcgc ccgctgggag acttttttcg ccgccggatg
    61081 cggggcaaaa atgacgctgt tgcccgcggc aatcaggctg atggcgttgt taattacggt
    61141 tgccgccggg ttagtggaag gcgtcactga agccaccacg ccccagggtg cgttttcaat
    61201 cagggtcggg ccgttgtcgc cagtcagcac ttgcggagag aggcactcaa cgcctggtgt
    61261 gccgcgcgcc tgagcgacgt ttttggcaaa tttatcttca acgcgcccca tgccggtttc
    61321 actgacggca agttccgcta aatctctggc gtgtttttcg cctgcttcac gaatggcagc
    61381 aatggctaac tggcgcattg ccacgctttt taacccttgc tgggcgactt tggctgccgc
    61441 aacggcgtca tccagggacg cgaaaacgcc catctcatga acggcggcgg gcggcgtgtc
    61501 actgctttgc attttcagca gtaccgcttt caccacctgt tcaatatcct gttgattcat
    61561 gatgttctgc cttatttgtg gaaaatgacc tgaccgccag acaccacctc atcgacaatg
    61621 ccaatcacgc acagatcgac cggtgacgtt tcgcttttat gcgcctggcg ggcggaactg
    61681 ccactcacca gtaacaccca ctccccggtt cccgcgccaa tattgtcgat ggcgacggcg
    61741 cattgcccgt caggattacc ttgtggatca atcatttcca ccatcagcaa tttgtcatgc
    61801 gccagtccgt gatggcgtac ggtacaaaca atttgtccag tgacgactgc cagtttcata
    61861 cccgcctccg tggcgtattt caggtaaaag ctccccctac cctccgcaga aggtaaaatg
    61921 aaaaaggaga gagcgtgacg cccgaatcga cgtcacacag ggtgattaca ggttgctgct
    61981 atcgcctttc aggccgatcg ggaagacttc ttccaggtcg ccgtgcggac gcgggataac
    62041 gtgtacagat accagctcgc cgatacgctg tgccgctgcg gcacctgcat cggtcgcggc
    62101 tttacaggct gcaacatcac cacgaaccat ggcagtacac aggccgccgc caatctgctt
    62161 aacaccaacc agcttgacgc gcgcagcttt aaccatcgcg tcagaagcct caatcagtgc
    62221 aaccaggccc cgggtttcga tcattcctaa tgcttccatt gtgctttcct ctttatcagg
    62281 gtccagaacg ggaccgttca ttcaaccagt gtttgtaaac tgctttcgcg gttcacttct
    62341 gtctgacgcg gcacagctgc caccagcgcc agttcgataa tttcctgcac gctacaacca
    62401 cgagagagat cgtgcatcgg cgcggcaagt ccttgtatca atggcccgac ggcacgatat
    62461 ccgccaagtc gttgtgcgat tttgtagcca atatttccgg cttccagcga cggaaaaacc
    62521 atcacattag ctttgccctg taacgggctg gcaggcgctt tttgcgccgc cacttccggc
    62581 acgaaggcgg cgtcaaactg caactcgcca tcgacaacca gctttggtgc gcgctcacgg
    62641 acgatttctg tcgcctgctg gacgttggca acacaggggt gacgggcact accgttgctg
    62701 gaaaacgaca gcatcgccac gcgcggttct tctccggtga tggcgcgcca ggtttcggcg
    62761 ctggcaagcg cgatatccgc cagttgtgcc gccgtcggct gtggcaccac gctgcaatcg
    62821 gcaaaaccca acgccggacc gctgtactgt ggcagcatca ggaaaatgga tgagagcgtt
    62881 ttacagcctg gctgcaagcc gataatgcgt aatccggcac gcagcacatt cgccgtggaa
    62941 gagaggttgc ccgcgataca gacatccgct ttaccggcgc tgaccattgc agcggcgaac
    63001 atcagcggat cggtaagttt ttccagcgca tccggcggcg ttttttcgcc cgcgcgggcc
    63061 agccagcgat gagcaaattc ttcccgcatt gcgaggttgc catgcggatc tatcacctgt
    63121 agcccgtcca tcgccacgcc gtgactgagc gcaaactgac gaagttcaaa cggattggcg
    63181 accagaatgg gcgttgccag accttgttga tgtaaatatt gcgcagcttt cagcacacgt
    63241 tgatctaacg catccggaaa aactactctg gcgggcgctc gcaacgccag ttcacgacaa
    63301 cgtttaataa tcattgcgtt tcccccagtc gttgttggat ctgcttcacc gttagcggct
    63361 gcttcgttac gctcaggatc atcatcacgt agaccgtgct ggaaaggcgg ttcagcgcct
    63421 gcaaaatgtc cgggcgtaat acttcaaagc tgcgggtgat aaagacctgc gccgctacgg
    63481 tttctgtttc ccgcactttg gtgcgtagca gattgagcaa cgccgcatcg cgcccgtggc
    63541 tggcttccgg caccagatga tcgtggtcga gataacgcag cggctggtga gaaagccgat
    63601 gcagatcttc gtcagaaagc ccgacaatcg cttgctcgcc cagcggttcc cccagcgcat
    63661 cggcacgcat aatgttgcca agacgcgagc ggatgtccgc cagccacggc tgccacggtt
    63721 ctgccagttc aatttgcagc cacactgcca gcgcaatggt gctgtcgaga acagcgcgaa
    63781 aacccagacg cggatcgctt ttggcaacca ttttttccgc cgacaggtga gtcagcgtat
    63841 ccggcttttt tgccaccggc tggcggcaca gttcgcagca cgcctgcgga tgttcatcgc
    63901 tactggtcag cccgtgaacg ggctgcggct gctgctgttc atcgtcaaca aacaggcggc
    63961 cctgctcgtc aataaacttg atgcgcagat ggcggctttc cagtaactcc cgggcagagg
    64021 gcgtcaggcg actgtccgca gggagatgga tctctgcgcc ttcgctgagc gtatggttcg
    64081 ctcttagcca tgcttcggtg atgaaatctt tcataaggat tgccagttag ccggccaggc
    64141 gacatacagg aatttcacgc tggatgtcgt accaaattcg atgctggagc ctttcgggat
    64201 aaacatcaca tcgcccgctt tggcgatcat agtttcgcct tcgtggcgaa catgcagctc
    64261 cccttccagc accatgtcga tttcgtcgta gttcagggtc cacggaaaga aggcgttctc
    64321 ccactgcatg aaaccagcgg ccatactgct gccgtcgtct ccggtcacga gatcagtcaa
    64381 gcctacgcag tgcggttccg cgccatcgaa acgaccaaac ttgacgctgc tgccatcaat
    64441 aactttgatg ccgcctttgc cggtcaccga tttaaagctc ggctgcagtg caccctgttc
    64501 cagcgactgt ttttccttca tcactttttc catcagctgc gcgaccaggc tttcggtaaa
    64561 ctgaccttcc ggcagttggg cgataatggt ttcacggatg cgctggcttt cggttttatc
    64621 ggctgatgcg ctggcgggaa cagacgccgt taccgggatc gattcatcac attcggtgat
    64681 ggtaaaaccc aacagatcag ccacttcacg agcttccggg gtaataatgc tggcgcgcag
    64741 aaccacggac attgccagtt cgccgcgcgc gtgtgcttca cgaatatcat tcgctgtgat
    64801 gagttttttc acctgcttcc tcctgtttgg tgagagatgc cagataatcc accagttgct
    64861 gcacgctttg cgggtcgtgg ctgtttagct cgaaaatcgg ctcttcgaag cccgtctcaa
    64921 gcaataactt tcgcgttgcg gcgacgtcag catctggcat gtccgtttta ctgatgacgg
    64981 cgatttgccg tttgctgacg ccaatatcca gcaacccggc aggcaaccga ctttccgggt
    65041 cattcgcgcc gtggacatag atcagcatat ccacatcctg tagcgtggta attaaggcgt
    65101 gataccagcg gggatggcta aaatattcac ccggcgtatc aatatcgcca ttatcattaa
    65161 attccacggc ctgtgttttt cttgcgaggg tataattccc ctgcaacgca ttaaataacg
    65221 ttgtttttcc tgccccgacg gtacccacaa acgcaattcg tttcatgaat gcctcgtatt
    65281 aacttttggt catttcacaa agcgtataat ttaataagcg tcctaaacca ctgacggttt
    65341 gtgataacgc ttcttctact gcgcccaccg agccataaat caccagcgcg ccactaaaac
    65401 gatcgagaaa accgatatgc acatcggcgg ctttcaacgc taaatcaccg gcgatcatcg
    65461 ccgtttctcc gggagttagc gtcataatgc cgattgcgcc cgcatccgga acgccgattt
    65521 tcttcgccag ttcctcgccg ggatgcgcga tgagatgcgc cagtgtgacc tgtttaccgg
    65581 gcacaaattc ctgaatgatg cgttctttat ccatgagtcg ccgcctgtga aaaactttcg
    65641 tgtatcgtga caatttttcg tcagagtaaa taacaaaatt cggcaagcgc gtttaaaagg
    65701 tgaggtagat cactaagaat ggagagatat ttgctgtggt gc
//
LOCUS       DAFGPF010000011        65403 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFGPF010000011 DAFGPF010000000
VERSION     DAFGPF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 65403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65403
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.011"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..765
                     /gene="gatY"
                     /locus_tag="LSX49_000880"
     CDS             <1..765
                     /gene="gatY"
                     /locus_tag="LSX49_000880"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBL7167323.1"
                     /translation="MQVVVETAASMHAPVIIAGTPGTFTHAGTENLMALVSAMAKQYH
                     HPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVE
                     AELGQLGGQEDDVQVNEADALYTNPVQAREFAEATGIDSLAVAIGTAHGMYARAPALD
                     FSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLT
                     EHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA"
     gene            794..2056
                     /gene="gatZ"
                     /locus_tag="LSX49_000881"
     CDS             794..2056
                     /gene="gatZ"
                     /locus_tag="LSX49_000881"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HBL7167324.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGMTPADFREFVFAIADKVGFARERIILGGDHLGPNCWQQENADAA
                     MEKSVELVKAYVRAGFSKIHLDASMSCADDSIPLAPETVAERAAVLCLAAESVATDCQ
                     REQLNYVIGTEVPVPGGEASAIQSVHITQVEDAANTLRTHQKAFIARGLAEALTRVIA
                     IVVQPGVEFDHSNIIHYQAQEAQALAQWIEKTKMVYEAHSTDYQTQAAYRELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQELIAPENSSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQS
                     GELSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            2066..2518
                     /gene="gatA"
                     /locus_tag="LSX49_000882"
     CDS             2066..2518
                     /gene="gatA"
                     /locus_tag="LSX49_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HBL7167325.1"
                     /translation="MTNLFVRGGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVLFQQADDDNDVAVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPEPQLKEYFTKYVLDSDE"
     gene            2549..2833
                     /gene="gatB"
                     /locus_tag="LSX49_000883"
     CDS             2549..2833
                     /gene="gatB"
                     /locus_tag="LSX49_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HBL7167326.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQSHNIPVELIQCRVNEI
                     ETYMDGVHLICTTAKVERSFGDIPLVHGMPFVSGVGIEALQNKILTILQG"
     gene            2837..4191
                     /locus_tag="LSX49_000884"
                     /pseudo
     CDS             2837..4191
                     /locus_tag="LSX49_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
     gene            4239..5279
                     /gene="gatD"
                     /locus_tag="LSX49_000885"
     CDS             4239..5279
                     /gene="gatD"
                     /locus_tag="LSX49_000885"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL7167327.1"
                     /translation="MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR
                     IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQ
                     CAKYDFIGSRRDGGFAEYIVVKRNNVFALPADMPIEDGAFIEPITVGLHAFHLAQGCE
                     NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSREMSAP
                     QIQGVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKI
                     LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIA
                     RNAMPGKVLLIP"
     gene            5385..6158
                     /locus_tag="LSX49_000886"
     CDS             5385..6158
                     /locus_tag="LSX49_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7167328.1"
                     /translation="MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLE
                     QKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVI
                     LDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
                     IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSVSGAMVTAANKVIAVLDSSKFNR
                     RGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(6240..7139)
                     /gene="yegS"
                     /locus_tag="LSX49_000887"
     CDS             complement(6240..7139)
                     /gene="yegS"
                     /locus_tag="LSX49_000887"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HBL7167329.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRITWEKG
                     DAARFVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     GVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     GLLQLRIFTGDEIIPTLVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            7554..7871
                     /locus_tag="LSX49_000888"
     CDS             7554..7871
                     /locus_tag="LSX49_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310918.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167330.1"
                     /translation="MKKIAAISLISIFLMSGCAVHNDETSIGKFGLAYKSNIQRKLDN
                     QYYTEAEASLARGRISGAENIVKNDAAHFCVTQGKKMQIVKLKTEGAGLHGVARLTFK
                     CGE"
     gene            complement(8371..9732)
                     /gene="yegQ"
                     /locus_tag="LSX49_000889"
     CDS             complement(8371..9732)
                     /gene="yegQ"
                     /locus_tag="LSX49_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HBL7167331.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEHMENAKGEAMPVAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(9879..10211)
                     /locus_tag="LSX49_000890"
     CDS             complement(9879..10211)
                     /locus_tag="LSX49_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HBL7167332.1"
                     /translation="MAGWFELSKSSDNQFRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            complement(10391..11113)
                     /gene="baeR"
                     /locus_tag="LSX49_000891"
     CDS             complement(10391..11113)
                     /gene="baeR"
                     /locus_tag="LSX49_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HBL7167333.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            complement(11110..12513)
                     /gene="baeS"
                     /locus_tag="LSX49_000892"
     CDS             complement(11110..12513)
                     /gene="baeS"
                     /locus_tag="LSX49_000892"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HBL7167334.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIK
                     HGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPVPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
                     RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSED
                     ELGRLAEDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TLASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPIDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFAD
                     SAPGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     LSITVELPLERDLQREV"
     gene            complement(12510..13925)
                     /locus_tag="LSX49_000893"
     CDS             complement(12510..13925)
                     /locus_tag="LSX49_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7167335.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLAIAGLVAVGVVALVLYLLHAQNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMASIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            complement(13926..17003)
                     /gene="mdtC"
                     /locus_tag="LSX49_000894"
     CDS             complement(13926..17003)
                     /gene="mdtC"
                     /locus_tag="LSX49_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HBL7167336.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG
                     ALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEV
                     EQTLVISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRML
                     VALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRGERSETAQ
                     QIIDRLRKKLAKEPGANLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQEDNGAEMNLIYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRMRFSRKPKQAVTE"
     gene            complement(17004..20126)
                     /gene="mdtB"
                     /locus_tag="LSX49_000895"
     CDS             complement(17004..20126)
                     /gene="mdtB"
                     /locus_tag="LSX49_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HBL7167337.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSESVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKI
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SRFARHEEEA"
     gene            complement(20126..21373)
                     /gene="mdtA"
                     /locus_tag="LSX49_000896"
     CDS             complement(20126..21373)
                     /gene="mdtA"
                     /locus_tag="LSX49_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HBL7167338.1"
                     /translation="MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQ
                     QSPAGGRRGMRAGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLMALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKAASREDTKKGARS"
     gene            21652..21708
                     /locus_tag="LSX49_000897"
     CDS             21652..21708
                     /locus_tag="LSX49_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HBL7167339.1"
                     /translation="MMKWIIIVVLLVISFPAY"
     gene            21980..22036
                     /locus_tag="LSX49_000898"
     CDS             21980..22036
                     /locus_tag="LSX49_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HBL7167340.1"
                     /translation="MMKLLIIVVLLVISYPAY"
     gene            22254..22913
                     /locus_tag="LSX49_000899"
     CDS             22254..22913
                     /locus_tag="LSX49_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL7167341.1"
                     /translation="MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGL
                     VTFRDELLADSLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAQGDTPMGSAITK
                     ALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFTIG
                     VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            22910..23671
                     /gene="pphC"
                     /locus_tag="LSX49_000900"
     CDS             22910..23671
                     /gene="pphC"
                     /locus_tag="LSX49_000900"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase PphC"
                     /protein_id="HBL7167342.1"
                     /translation="MSWRLVYASAVGTSHISADLPCQDACQIQVAWLNDQQPLLSVFV
                     ADGAGSASQGGEGAMLAVNEAMAYMSQKVQGGELGLNDVLATDIVLTIRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDLGHGLQLPLTPMVGEYANMTHFI
                     TDEDAVSRLDTFTSTERAHKVAAFTDGIQRLALNMLDNSPHMPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWLP"
     gene            23668..25608
                     /gene="yegI"
                     /locus_tag="LSX49_000901"
     CDS             23668..25608
                     /gene="yegI"
                     /locus_tag="LSX49_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310906.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
                     /protein_id="HBL7167343.1"
                     /translation="MKPTLYTATGECVTPGRELGKGGEGAVYDIEEFVESVAKIYHTS
                     PPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYS
                     PAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVMIDS
                     DSFQINANGTLHLCEVGVSHFTPPELQTMPSFVGFERTENHDNFGLALLIFHVLFGGR
                     HPYSGVPLISDAGNALETDIAHFRYAYASDNQRRGLKPPPRSIPLSMLPGDVEAMFQQ
                     AFTESGVATGRPTAKAWVAALDLLRQQLKKCTVSAMHVYPGHLADCPWCALDNQGVIY
                     FIDLGEEVITTGGNFVLAKVWAMVMASVAPPALQLPLPDHFQAAGRPLPSGLLRREYI
                     ILIEIALSGLSLLLCGLQTEPRYIILVPVLAAIWIIGSLTSKAYKVEVQRRREAFNRA
                     KMDYDHLVSQIQQLGGLEGFIAKRAMLEKMKDEILGLPEEEKRDLAALHDTARERQKQ
                     KFLEGFFIDVASIPGVGPARKAALRSFGIETAADVTRRSVKQVRGFGDHLTQAVIDWK
                     ASCERRFVFRPNEAVTPADRQAVMAKMAAKRHRLESALTVGATELQRFRLQAPARTMP
                     LMEPLRQAAEKLAQAQADLSRC"
     gene            complement(25621..26973)
                     /gene="yegD"
                     /locus_tag="LSX49_000902"
     CDS             complement(25621..26973)
                     /gene="yegD"
                     /locus_tag="LSX49_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBL7167344.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPHLLKMENDSTLLPSMLCAPTRE
                     AVSEWLYRHHDVPADDDETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPEAITQAVIGRPINF
                     QGLGGDEANTQAQGILERAAKRAGFKDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNDLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEESKIALSSVAETRASLPFISDELATLISQQGLESALNQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALTEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            27107..27955
                     /gene="alkA"
                     /locus_tag="LSX49_000903"
     CDS             27107..27955
                     /gene="alkA"
                     /locus_tag="LSX49_000903"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HBL7167345.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVSGVETVADSYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSVGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAGR
                     PGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTSRVAQLYGERLDDFPDYVCFPTPQR
                     LAVADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDEA"
     gene            complement(28062..31379)
                     /locus_tag="LSX49_000904"
     CDS             complement(28062..31379)
                     /locus_tag="LSX49_000904"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBL7167346.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKLLPWYNPLQNLADWLRLALGSAIIPPLLGGVLVVLLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQSNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPN
                     IFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIT
                     VKDGIRHIRALANRVLNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANRASFEKQLRILLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGRGRVTIYEPQQVAAHSERAV
                     MSLDEQWRMIKENQLMMIAHGVASPRIPQARNLWLISLKLWSCEGEIIDEQTFRRSFS
                     DPALSHALDRRVFHDFFQQAAKAIASKGLSIALPLSVAGLSSATLVNELIELLENSPL
                     SPRLLHLIIPADAILDHAESVQKLRLAGCRIVFSQVGRDLQIFNSLKANMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            31697..32338
                     /gene="udk"
                     /locus_tag="LSX49_000905"
     CDS             31697..32338
                     /gene="udk"
                     /locus_tag="LSX49_000905"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBL7167347.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            32430..33011
                     /gene="dcd"
                     /locus_tag="LSX49_000906"
     CDS             32430..33011
                     /gene="dcd"
                     /locus_tag="LSX49_000906"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HBL7167348.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            33033..34886
                     /gene="asmA"
                     /locus_tag="LSX49_000907"
     CDS             33033..34886
                     /gene="asmA"
                     /locus_tag="LSX49_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HBL7167349.1"
                     /translation="MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRADNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTLSLNGTVDASDYPHDLTA
                     AIEQINWQLQGADLPKQGIQGQGSFQAQWQESHKRLSFNQISLTANDSTLSGQAQVTL
                     TEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGQSQSTLPRPVISSRIDEPAYQ
                     GLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLD
                     ATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQG
                     QAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVT
                     LNDMQGQSPVLALTGEGMLNLADQTCDTQFDIRVVGGWNGESKLIDFLKETPVPLRVY
                     GNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM"
     gene            complement(35338..36921)
                     /locus_tag="LSX49_000908"
     CDS             complement(35338..36921)
                     /locus_tag="LSX49_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HBL7167350.1"
                     /translation="MEWIADPSIWAGLITLIVIELVLGIDNLVFIAILAEKLPPKQRD
                     RARVTGLLLAMLMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAVGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEALNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEDEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLRKDGEMEYEV"
     gene            complement(37122..37271)
                     /locus_tag="LSX49_000909"
     CDS             complement(37122..37271)
                     /locus_tag="LSX49_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167351.1"
                     /translation="MVIEYWLSNNAGGSVTANGIAGKVTIRQLAIFKNYIKCRSIWFL
                     GVSLD"
     gene            37581..38720
                     /gene="wza"
                     /locus_tag="LSX49_000910"
     CDS             37581..38720
                     /gene="wza"
                     /locus_tag="LSX49_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein Wza"
                     /protein_id="HBL7167352.1"
                     /translation="MMKSKMKLMPLLVSVTLISGCTVLPGSNMSTLGKDVIKQQDADF
                     DLDKMVNVYPLTPRLIDQLRPRPNVARPNMTLESEIANYQYRVGPGDVLNVTVWDHPE
                     LTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKVHVVGKTLAEIRSDITGRLATYIADPQ
                     VDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTILDAINAAGGLTDTADWRNVVLTHN
                     GREERISLQALMQNGDLNQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSGM
                     TLTEALGNAEGIDMTTSNASGIFVIRPLKGESGRNGKIANIYQLDMSDATSLVMATEF
                     RLQPYDVVYVTTAPVSRWNRLINQLLPTISGVRYMTDTASDIHNW"
     gene            38726..39169
                     /gene="wzb"
                     /locus_tag="LSX49_000911"
     CDS             38726..39169
                     /gene="wzb"
                     /locus_tag="LSX49_000911"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase Wzb"
                     /protein_id="HBL7167353.1"
                     /translation="MFNNILVVCVGNICRSPTAERLLQRYHPELKVESAGLGALVGKG
                     ADPTAISVAAEHQLSLEGHCARQISRRLCRNYDLILTMEKRHIERLCEMAPEMRGKVM
                     LFGHWDNECEIPDPYRKSRETFAAVYALLERSAHQWAQALNAEQV"
     gene            39172..41334
                     /gene="wzc"
                     /locus_tag="LSX49_000912"
     CDS             39172..41334
                     /gene="wzc"
                     /locus_tag="LSX49_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416564.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="HBL7167354.1"
                     /translation="MTEKVKQHAAPVTGSDEIDIGRLVGTIIEARWWVIGITAVFALC
                     AVVYTFFATPIYSADALVQIEQSSGNSLVQDIGSALANKPPASDAEIQLIRSRLVLGK
                     TVDDLDLDIAVSKNTFPIFGAGWERLTGRQNETVKVTTFNRPKEMADQVFTLNVLDNK
                     NYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHASPGSEFTVTKYSTLGMINQLQNSL
                     TVTENGKDAGVLSLTYTGEDREQIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQL
                     PEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLY
                     TKVHPAYRTLLEKRQALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNK
                     EQELKITEASTVGDVRIVDPAITQPGVLKPKKVLIILGAIILGLMLSIVGVLLRSLFN
                     RGIESPQVLEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIE
                     AIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLIDCDMR
                     KGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSER
                     FAELVKWASKNYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSR
                     FEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK"
     gene            41463..42302
                     /gene="wcaA"
                     /locus_tag="LSX49_000913"
     CDS             41463..42302
                     /gene="wcaA"
                     /locus_tag="LSX49_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaA"
                     /protein_id="HBL7167355.1"
                     /translation="MKDNPLISIYMPTWNRQQLAIRAIKSVLRQDYNNWEMIIVDDCS
                     TSWEQLQQYVTALNDPRITYIHNDINSGACAVRNQAIMLAQGEYITGIDDDDEWTPNR
                     LSVFLAHKQQLVTHAFLYANDYVCQGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQV
                     FTWAWRFKECLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSSP
                     KKFSGYFHFYRKHKDKFDRASKKYQLFTLYQIRNKRMTWRTLLTLLSVRNGKRLADGI
                     RGR"
     gene            42305..42793
                     /gene="wcaB"
                     /locus_tag="LSX49_000914"
     CDS             42305..42793
                     /gene="wcaB"
                     /locus_tag="LSX49_000914"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaB"
                     /protein_id="HBL7167356.1"
                     /translation="MLEDLRANSWSLRPCCMVLAYRAAHFCSVWRKKNVLNNLWAAPL
                     LVLYRIITECFFGYEIQAAATIGRRFTIHHGYAVVINKNVVAGDDFTIRHGVTIGNRG
                     ADNMACPHIGNGVELGANVIILGDITIGNNVTVGAGSVVLDSVPDNALVVGEKARVKV
                     IK"
     gene            42790..44007
                     /gene="wcaC"
                     /locus_tag="LSX49_000915"
     CDS             42790..44007
                     /gene="wcaC"
                     /locus_tag="LSX49_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaC"
                     /protein_id="HBL7167357.1"
                     /translation="MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGK
                     ESVSHQNYPQVIKHTPRMTAMANIALFRLLNRDLFGNFNELYRTITRTPGPVVLHFHV
                     LHSYWLNLKSVVRFCEKVKNHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP
                     TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIIN
                     NGIDMATEAILADLPPVRETQGKPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHT
                     FGKFSPFTAGNVVNHGFETDKRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVI
                     ATHSDAAREVLQKSGGKTVSEEDVLQLVQLSKPEIAQAIFGTTLAEFSQRSRAAYSGQ
                     QMLEEYVNFYQNL"
     gene            43982..45202
                     /gene="wcaD"
                     /locus_tag="LSX49_000916"
     CDS             43982..45202
                     /gene="wcaD"
                     /locus_tag="LSX49_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative colanic acid polymerase WcaD"
                     /protein_id="HBL7167358.1"
                     /translation="MSTSIRICSYLLLPLIYLLVNVKIAQLGESFPITIVTFLPVLLL
                     LFLERISVKKLMIALGIGAGLTAFNYLFGQSLDASKYVTSTMLFVYIVIIIGMVWSIR
                     FKTISPHNHRKILRFFYLVVGLVVVLAAVEMAQIILTGGSSIMESISKYLIYSNSYVL
                     NFIKFGGKRTTALYFEPAFFALALISIWLSIKQFGIKTPKTDAMILAGIILSGSFSGV
                     MTFILFYLLEWAFQYLNKEAIKKKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGS
                     SSYYRIVGPLVMVGYSLTHIDGVVRFGSLYEYVASFGIFNGADVGKTIDNGLYLLIIY
                     FSWFAVFLSLWYMGKVIKMMINAFGDNRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIV
                     CPFILRKALNIHPK"
     gene            45283..46029
                     /gene="wcaE"
                     /locus_tag="LSX49_000917"
     CDS             45283..46029
                     /gene="wcaE"
                     /locus_tag="LSX49_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaE"
                     /protein_id="HBL7167359.1"
                     /translation="MLLSIITVAFRNLEGIVKTHASLAHLAQADDISFEWIVVDGGSN
                     DGTREYLENLNGIYNLHFVSEPDNGIYDAMNKGIEMAQGKFALFLNSGDIFHQDAAYF
                     VRKLKVQKDNVMITGDALLDFGDGHKIKRSAKPGWYIYHSLPASHQAIFFPVSGLKKW
                     RYDLEYKVSSDYALAAKMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQ
                     ILHVPGFWAELSWHLRQRTTSKTKALYNKS"
     gene            46045..46593
                     /gene="wcaF"
                     /locus_tag="LSX49_000918"
     CDS             46045..46593
                     /gene="wcaF"
                     /locus_tag="LSX49_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaF"
                     /protein_id="HBL7167360.1"
                     /translation="MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRA
                     FLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDEVNLYTLGEITIGAHSVISQ
                     KSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKS
                     LPANVVCRGHPAVVIRKRVETE"
     gene            46620..47741
                     /gene="gmd"
                     /locus_tag="LSX49_000919"
     CDS             46620..47741
                     /gene="gmd"
                     /locus_tag="LSX49_000919"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBL7167361.1"
                     /translation="MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRF
                     EGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWK
                     PEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES"
     gene            47744..48709
                     /gene="fcl"
                     /locus_tag="LSX49_000920"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
     CDS             47744..48709
                     /gene="fcl"
                     /locus_tag="LSX49_000920"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
                     /EC_number="1.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HBL7167362.1"
                     /translation="MSKQRIFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDS
                     RAVHDFFASESIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKL
                     LFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMA
                     AASIHVMELAHEVWQENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG"
     gene            48712..49191
                     /gene="gmm"
                     /locus_tag="LSX49_000921"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
     CDS             48712..49191
                     /gene="gmm"
                     /locus_tag="LSX49_000921"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HBL7167363.1"
                     /translation="MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGY
                     WFVPGGRVQKDETLEAAFERLTMAELGLRLPITAGQFYGVWQHFYDDNFSGSDFTTHY
                     VVLGFRFRVAEEELLLPDEQHDDYRWLTPDALLASDNVHANSRAYFLAEKRAGVPGL"
     gene            49188..50411
                     /gene="wcaI"
                     /locus_tag="LSX49_000922"
     CDS             49188..50411
                     /gene="wcaI"
                     /locus_tag="LSX49_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis fucosyltransferase
                     WcaI"
                     /protein_id="HBL7167364.1"
                     /translation="MKILVYGINYSPELTGIGKYTGEMVEWLAAQGHEVRVITAPPYY
                     PQWQVGENYSAWRYKREEGAAMVWRCPLYVPKQPSTLKRLLHLGSFAVSSFFPLMAQR
                     RWKPDRIIGVVPTLFCTPGMRLLAKLSGARTVLHIQDYEVDAMLGLGLAGKGKGGKVA
                     QLATAFERSGLHNVDNVSTISRSMMNKAIEKGVAAENVIFFPNWSEIARFQHVADADV
                     DALRNQLGLPDNKKIILYSGNIGEKQGLENVIEAADRLRDEPLIFAIVGQGGGKARLE
                     KMAQQRGLRNMQFFPLQSYDALPALLKMGDCHLVVQKRGAADAVLPSKLTNILAVGGN
                     AVITAEAHTELGQLCETFPGIAVCVEPESVEALVAGIRQALLLPKHNTVAREYAERTL
                     DKENVLRQFINDIRG"
     gene            50414..51850
                     /gene="cpsB"
                     /locus_tag="LSX49_000923"
     CDS             50414..51850
                     /gene="cpsB"
                     /locus_tag="LSX49_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="HBL7167365.1"
                     /translation="MAQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTT
                     ICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAA
                     KRHSPENDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGY
                     IRRGEVSAGEQDTVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELK
                     KYRPDILDACEKAMSAVDPDLDFIRVDEEAFLACPEESVDYAVMERTADAVVVPMDAG
                     WSDVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTK
                     DAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITV
                     KPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKI
                     PLDLIEVRSGSYLEEDDVVRFADRYGRV"
     gene            51955..53325
                     /gene="cpsG"
                     /locus_tag="LSX49_000924"
                     /gene_synonym="manB"
     CDS             51955..53325
                     /gene="cpsG"
                     /locus_tag="LSX49_000924"
                     /gene_synonym="manB"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis phosphomannomutase
                     CpsG"
                     /protein_id="HBL7167366.1"
                     /translation="MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLF
                     GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINR
                     VEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEARTRTL
                     LTLLNE"
     gene            53381..54775
                     /gene="wcaJ"
                     /locus_tag="LSX49_000925"
     CDS             53381..54775
                     /gene="wcaJ"
                     /locus_tag="LSX49_000925"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HBL7167367.1"
                     /translation="MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSF
                     LYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSVIFSAGLVAFN
                     NDFDTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLM
                     ESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGA
                     RVKKLVHQLADTTCSVLLIPDVFTFNILHSRIEEMNGVPVVPLYDTPLSGVNRLIKRA
                     EDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVME
                     NDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYR
                     QLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIV
                     FLTVFKGFVNKAAY"
     gene            54777..56255
                     /gene="wzxC"
                     /locus_tag="LSX49_000926"
     CDS             54777..56255
                     /gene="wzxC"
                     /locus_tag="LSX49_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid undecaprenyl disphosphate flippase
                     WzxC"
                     /protein_id="HBL7167368.1"
                     /translation="MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLL
                     TVSLVIIALADTLSDFGIANSIIQRKEISHLELTTLYWLNVGLGIVVCVAVFLLSDLI
                     GDLLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTFTV
                     VSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTA
                     DSIINYLNTNLSTLVLARILGAGVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQ
                     DDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKWSSIIPVLQLLCIVG
                     LLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIIIGGQMAGAIGVTLGFLLVQI
                     INTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTLVVSYALGIVLKGQLALGMLLA
                     VQIATGVLAFVVMIVLSRHPLVVEVKRQFCRSEKMKMLLRAG"
     gene            56724..58004
                     /gene="wcaK"
                     /locus_tag="LSX49_000927"
     CDS             56724..58004
                     /gene="wcaK"
                     /locus_tag="LSX49_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis pyruvyl transferase
                     WcaK"
                     /protein_id="HBL7167369.1"
                     /translation="MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPV
                     SSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNI
                     AIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGP
                     FQDKQFNQLANYVFGHCDALILRESVSLDLMKRSNITTAKVEHGVDTAWLVDHHTEDF
                     TASYAVQHWLDVAAQQKAVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQV
                     IALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGT
                     RLHSAIISMNFATPAIAINYEHKSAGIMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQ
                     LPALNARLNEAVSRERQTGMQMVQSVLERIGEVK"
     gene            58001..59221
                     /gene="wcaL"
                     /locus_tag="LSX49_000928"
     CDS             58001..59221
                     /gene="wcaL"
                     /locus_tag="LSX49_000928"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaL"
                     /protein_id="HBL7167370.1"
                     /translation="MKVGFFLLKFPLSSETFVLNQITAFIDMGFEVEIVALQKGDTQN
                     THAAWTKYNLAARTRWLQDEPTGKVAKLRHRASQTLRGIHRKNTWQALNLKRYGAESR
                     NLILSAICGQVATSLHADVFIAHFGPAGVTAAKLRELGVIRGKIATIFHGIDISSREV
                     LNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTRFSPRPVKA
                     PATPLEIISVARLTEKKGLHVAIEACRQLKEQGVAFRYRILGIGPWERRLRTLIEQYQ
                     LEDVVEMPGFKPSHEVKEMLDDADVFLLPSVTGADGDMEGIPVALMEAMAVGIPVVST
                     LHSGIPELVEADKSGWLVPENDARALAQRLAAFSQLDSDELAPVVKRAREKVEHDFNQ
                     QVINRELASLLQAL"
     gene            59232..60626
                     /gene="wcaM"
                     /locus_tag="LSX49_000929"
     CDS             59232..60626
                     /gene="wcaM"
                     /locus_tag="LSX49_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HBL7167371.1"
                     /translation="MPFKKLSRRTFLTASSVLAFLHTPFARALPAQQSVNINDYNPHD
                     WIASFKQAFSEGQTVVVPAGLVCDNINTGIFIPPGKTLHILGSLRGNGKGRFVLQDGS
                     QVTGEGGGSMHNITLDVRGSDCTIKGLAMSGFGPVTQIYIGGKNKRVMHNLTIDNLTV
                     SHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHVIERINCT
                     NGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIK
                     ARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNF
                     RVNDIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFMRNINV
                     MQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRINHHIV
                     NVEKINFRLPERRE"
     gene            60801..61694
                     /gene="galF"
                     /locus_tag="LSX49_000930"
     CDS             60801..61694
                     /gene="galF"
                     /locus_tag="LSX49_000930"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalF"
                     /protein_id="HBL7167372.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLELRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDNASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQAVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     gene            62067..63152
                     /gene="rfbB"
                     /locus_tag="LSX49_000931"
     CDS             62067..63152
                     /gene="rfbB"
                     /locus_tag="LSX49_000931"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL7167373.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYFFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSGLDDEKKKNFRFHHISTDEVYGDLPHPDEVNSNETLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNSLEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVFTICDL
                     LDEIVPKEKSYREQITYVTDRPGHDRRYAIDAEKIGRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            63152..64051
                     /gene="rfbD"
                     /locus_tag="LSX49_000932"
     CDS             63152..64051
                     /gene="rfbD"
                     /locus_tag="LSX49_000932"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBL7167374.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPKFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGTGEIPWQEEDATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            64109..64987
                     /gene="rfbA"
                     /locus_tag="LSX49_000933"
     CDS             64109..64987
                     /gene="rfbA"
                     /locus_tag="LSX49_000933"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL7167375.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDVAVNKESGATVFAYHVNDPERYGVVEFDNNGTAISL
                     EEKPLEPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQVKVLAEPL
                     KKNAYGQYLLKMIKGY"
     gene            64992..>65403
                     /gene="rfbC"
                     /locus_tag="LSX49_000934"
     CDS             64992..>65403
                     /gene="rfbC"
                     /locus_tag="LSX49_000934"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBL7167376.1"
                     /translation="MNVIKTEIPDVLIFEPKVFGDERGFFFESFNQRIFEEAVGRKVE
                     FVQDNHSKSSKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVN
                     LSAENKRQLWIPEGFAHGFLVLSDLAEVLYKTNQY"
BASE COUNT        15990 a        16277 c        17504 g        15632 t
ORIGIN      
        1 atgcaagtgg tggtggaaac cgctgccagc atgcatgcgc cggtcatcat cgccggaacg
       61 cccggcacat ttactcatgc cggtacagaa aatctgatgg cgctggtcag cgcgatggcg
      121 aagcaatatc accatccact ggcgattcat ctcgaccatc acacaaaatt tgacgatatc
      181 gctcagaagg ttcgttctgg cgtgcgctca gtcatgattg acgcctcgca tttgcctttt
      241 gcgcaaaata tttcacgggt caaagaggtg gtggattttt gccatcgctt tgatgtcagc
      301 gtcgaagcgg agctggggca acttggcggc caggaagatg atgtgcaagt caatgaagca
      361 gatgcgttgt acaccaaccc cgttcaggcg cgtgaatttg ccgaggcaac cgggattgat
      421 tccctggcgg tcgccatcgg cacggctcac ggtatgtatg ccagagcacc ggcgcttgat
      481 ttttctcgac tggagaacat tcgccagtgg gtgaatttac cgctggtgct gcatggcgcg
      541 tcaggattat cgactaagga tattcagcaa accatcaaac tggggatatg caaaatcaac
      601 gttgcaacgg agctgaaaaa tgccttctcg caggcgttaa aaaattacct gaccgagcac
      661 cccgaagcga ccgatccccg tgattatttg cagtcggcta aatctgcaat gcgcgatgtg
      721 gtgagcaaag tgattgccga ttgtggctgc gagggcaggg cataacgcac ctgccattta
      781 acaaggaaaa aacatgaaaa cgttaattgc ccggcataaa gctggtgaac atattggcat
      841 atgttcagtc tgttctgcac atccgttggt tatcgaagcg gcgctggcat ttgatcgcaa
      901 cagcacgcgt aaagtgctga ttgaagcaac gtcaaaccag gtcaatcaat ttggcggtta
      961 taccggaatg acaccggcag actttcgcga atttgttttt gctattgccg ataaagtcgg
     1021 atttgctcgt gagcgtatta ttctcggcgg cgaccatctg ggaccaaact gctggcagca
     1081 agaaaatgcg gatgcggcga tggaaaaatc cgtcgagctg gtaaaggcat atgttcgtgc
     1141 cggcttcagt aaaattcatc ttgatgcgtc aatgtcctgc gctgacgatt ccataccgtt
     1201 agcgccagaa acggttgctg aacgtgccgc tgtgctttgt ctggcggcgg aaagtgtggc
     1261 gactgattgc cagcgtgagc aactgaacta tgtcattggc actgaagttc cggtcccggg
     1321 cggtgaggcc agcgccattc agtcagtaca catcacccag gttgaagatg ccgccaatac
     1381 tttacgcacg catcaaaaag cgtttattgc ccgcggtctg gcagaggcgt taacacgcgt
     1441 gattgccatc gtggtgcagc ctggtgtgga atttgaccat agcaatatta ttcattatca
     1501 ggcgcaagaa gctcaggcgt tggcgcaatg gatagaaaaa accaaaatgg tttatgaagc
     1561 gcattccacc gattaccaga ctcaggcggc ctatcgggaa ttagttcgcg atcattttgc
     1621 aattttgaaa gtcggtccgg cattaacctt tgcgttacgc gaggcgatat ttgcgctggc
     1681 gcaaattgag caggaactta tcgcccccga aaatagcagt ggttgcctgg cggtaattga
     1741 agaagtgatg ctcgacgaac cgcagtactg gaagaaatat tatcgcacgg gttttaacga
     1801 ttcattactg gatattcgtt acagcctgtc ggatcgtatt cgttattact ggccgcatag
     1861 ccggattaaa aatagcgtcg aaacgatgat ggtgaatctg gaaggcgtag acatcccact
     1921 gggcatgatt agtcagtatc ttccgaaaca atttgaacgc attcagtccg gggaattatc
     1981 agcaataccg catcagctta ttatggataa aatttatgat gttttgcgcg cctatcgcta
     2041 cggctgtgcg gaataaggac ggtatatgac taacctgttt gttcgtggcg gaatttcttt
     2101 tgtcgatcgt agcgaagttt taacccatat cggtaatgag atgctcgcga aaggtgtggt
     2161 tcatgatacc tggccacagg cattaattgc cagagaagca gaattcccta ccgggataat
     2221 gcttgagcag cacgccattg caataccgca ttgtgaggcg attcatgcta agtcgtcagc
     2281 catttatctg ttaaggccaa caaataaagt tctttttcag caagcggatg atgataacga
     2341 cgtggcggta tcgttggtta ttgcgttgat tgtggaaaat ccgcagcagc aattgaaact
     2401 tttacgctgt ttatttggca agttacaaca gcccgatatc gtcgagacac taatcactct
     2461 tcctgaaccc cagttaaagg aatacttcac aaagtatgtt ttagattcag acgaataaat
     2521 ccctctgtaa caataaaaag gactatttat gaaacgcaaa attattgtcg cttgcggagg
     2581 cgcggtagcg acctctacga tggcggcgga agaaattaaa gagttgtgtc agagtcataa
     2641 tattcctgtt gaattaatcc agtgtcgggt taatgaaata gaaacctata tggatggcgt
     2701 gcatttgata tgtactaccg ccaaagttga acgcagtttt ggcgatattc cgttagttca
     2761 cggcatgcct tttgtttctg gtgtcggtat cgaagcatta caaaataaaa ttctgactat
     2821 cttacagggg tgacctatgt tttcagaagt catgcgttat attctcgacc tcggccctac
     2881 ggtgatgctg ccgattgtca tcattatttt ttctaaaata ttaggcatga aggcaggcga
     2941 ttgctttaaa gcgggtctgc atatcgggat tggctttgtt ggcattggcc ttgtgattgg
     3001 cttaatgctg gattccattg gcccggcggc gaaagcgatg gcggaaaatt tcgacctgaa
     3061 tctgcatgtg gtcgatgtcg gctggccggg ctcttcaccc atgacctggg cgtcgcaaat
     3121 tgcgctggtg gcgattccga ttgcgattct ggttaacgtg gcgatgttac tgacccgtat
     3181 gacgcgggtg gtaaatgttg atatctggaa tatctggcat atgaccttca ccggcgcgtt
     3241 gctgcatctg gcaaccggtt catggatgat agggatggcg ggtgtggtaa ttcacgcggc
     3301 gtttgtttat aagctcggcg actggtttgc ccgcgatacc cgtgatttct ttgagctgga
     3361 aggcattgct attccgcacg gtacgtcggc gtatatgggg ccaattgctg tgctggtcga
     3421 tgctatcatc gagaaatccc aggcgttaac cgaattaaat ttagcgccga tgatattcag
     3481 cgcaaatttg gcccttttgg cgaaccggtc accgtgggtt ttgtgatggg gctgattatc
     3541 ggcatcctcg cgggttacga tgtcaaaggt gtattgcagc tggcggtaaa aacggcggca
     3601 gttatgctgc tgatgccacg ggtgattaaa cccatcatgg atggtttaac gcccatcgct
     3661 aagcaggccc gtagtcgttt acaggcgaag ttcggcggtc aggagttcct gattggcctt
     3721 gatccggcgt tgctgctggg acatacggcg gtggtatcgg caagcctgat ttttattcca
     3781 ctcaccattt taattgctgt ttgtgtgccg ggtaatcagg tgctgccgtt tggcgacctt
     3841 gccaccatcg gcttctttgt ggcgatggcg gtcgcggtgc atcgtggaaa tctgttccgc
     3901 accttaatct cgggtgtcat cattatgagc atcaccctgt ggatcgcgac gcaaactatt
     3961 ggtttgcaca cccaactggc ggctaatgcg ggcgcgttaa aagccggggg tatggtggct
     4021 tcaatggatc agggcggttc tcccattacc tggttactga ttcaggtttt ctccccgcaa
     4081 aatattcccg gtttcattgt tatcggcgca atttatctta ccggtatttt catgacctgg
     4141 cgtagagcgc gtggttttat taaacaagag aaagccgttc tcgcagaata atttttacct
     4201 gagggggagg ttatccccct taacaatcag gagtttttat gaaatcagtg gtgaatgata
     4261 ctgatggtat cgtgcgcgta gcagaaagcg tcattcctga aattaaacat caggatgagg
     4321 tgcgggtaaa aattgccagc tcgggcttat gtggttccga tttacccagg atatttaaaa
     4381 atggtgcaca ttattatcca ataacgttag gccatgaatt tagtggctat attgatgcgg
     4441 tgggatccgg tgttgatgat ttacaccccg gcgatgcggt tgcctgtgtg ccgttattac
     4501 cctgttttac ttgtccagag tgtctgaaag ggttttattc ccagtgcgca aaatatgatt
     4561 ttattggctc acggcgtgat ggtggatttg ccgaatatat tgtcgttaag cgaaacaatg
     4621 tctttgcact acctgcggat atgcctattg aggatggcgc ttttattgaa ccgattaccg
     4681 ttggcctgca tgcgttccat ttagcgcaag gatgtgagaa taaaaacgtt attattattg
     4741 gtgccggaac cattggcctg ctggcaattc agtgcgctgt cgcgctggga gcaaagagtg
     4801 tgacggctat cgacattagc tcagaaaaac tggcactggc aaaatctttc ggtgcgatgc
     4861 aaacatttaa cagccgtgaa atgagcgcgc cgcaaataca gggcgtttta cgcgagctgc
     4921 gctttaatca gcttatcctc gagacggctg gcgtcccgca aaccgtcgaa ctggcggtag
     4981 agattgccgg tcctcatgcc caactggcgc tggtgggcac gttgcatcag gatctgcatt
     5041 taacatctgc aacgtttggc aaaatattgc gtaaagagct gacggttatc ggcagttgga
     5101 tgaactactc cagcccttgg ccggggcagg agtgggaaac ggcgagccgg ttgctgacag
     5161 aacgtaagtt aagcctggag ccattaatcg ctcaccgtgg aagctttgaa agctttgccc
     5221 aggcggtgcg tgacatcgct cgtaatgcta tgccgggcaa agtgttgctc attccctgaa
     5281 accgcgggcc agcgtgatgc tggcccggta ttgtgcaaaa cagatcattc accaatggtt
     5341 ccccttcgtt tacactagcc acaattgaat atgggtaaat gacgatgaat tcattcgagc
     5401 gaaggaataa gatcatccaa ttagtgaatg aacagggaac cgtgcttgtt caggatctgg
     5461 cgggagtatt tgctgcctcg gaagcgacaa tccgtgccga tttgcgcttt ctcgaacaaa
     5521 aaggcgtggt tacgcgcttt catggcggtg cggcgaaaat aatgtcaggt aatagcgaaa
     5581 ccgagaccca ggaagtcggg tttaaagagc gatttcagct cgccagcgcg ccgaaaaaca
     5641 gaatagcgca ggcggcagtc aaaatgatcc acgaagggat gaccgttatt ctcgacagcg
     5701 gaagtaccac aatgcttatc gccgaaggat taatgaccgc caaaaatatc acggtgatta
     5761 ccaacagtct cccggcggcg tttgcccttt ccgaaaataa agacattact ctggtcgtct
     5821 gcggtggcac ggtccgccat aaaacgcgct cgatgcatgg atctattgct gaacgttccc
     5881 tgcaggatat taatgccgat ttaatgtttg tcggtgctga tggtattgat gcggttaatg
     5941 gtattacgac ctttaatgaa ggttattccg ttagcggtgc gatggtgaca gcggcgaata
     6001 aagtgattgc cgttcttgat tcatcgaaat ttaatcgtcg cggttttaat caggtactgc
     6061 caatcgaaaa aattgacatt attattaccg atgatgctgt gtctgaggtg gataaactgg
     6121 cattgcagaa gacacgggta aaattaatta cggtgtagta ttgttctgta tgccggataa
     6181 ggtgtttaca ccgtatccgg cattacggat tctctctggt tcaacagaga atagtttgat
     6241 taacgcaaca atggacaatc tggtggtaat cgacaacgca acgccgccgg aagtatttca
     6301 atatggaagt tttgcccact caacggttcg ccatcaagat taaaagtgat ttcgtgtggg
     6361 gcttgtatat caaaccacga cgaagcacct tcgataatat tcgggttatc ttcgtcagat
     6421 tttaaggttg atacgagagt cggaataatt tcatcgccgg taaaaatgcg cagttgcagc
     6481 aagccatcgt taattaatgc gttcgggcac aattgttgac cgccaccggc ctgacgcccg
     6541 ttaccaatac caatgaccag ggcgtcacct tgccagtgaa agttttcacc gcggatttca
     6601 caacggtccg gttgcagagt gtccatgcgc attaagccat gaatgatgta agagacgcca
     6661 cccagcgcgg cttttaattt ttccggcgtt tctgtggtaa tacgcgtccc aaacccgcct
     6721 gtcgccatat taataaaaca ggtttgtttg ttgacctgcg ccatatctat cgcaatggcg
     6781 ttaccggcaa ttgccagttt cagcgcctta tccagtgcct caggaatccc tacactagtg
     6841 gcaaaatcat tggcagttcc taatggtaaa attcccagcg cgggtatgtc atccccctca
     6901 cattgaatca atgccgtaga aacttcatta atggtgccat cgccaccacc ggcaatcact
     6961 gttgcgacgc ctaacttccg ggcctcctct acaaatcgtg cagcatcgcc tttctcccag
     7021 gtgatccgca catggatcgt cattccttcc tcacgcaaca gcataattgc ttcgcgcaag
     7081 ggtagattgt cagtactttt gccattaaga atcagtaagc tggcgggaaa ttctgccatg
     7141 atcgtatgtg cctttatgat tggtctgtag atagtgtaga gcagaaaaga aaaggtggag
     7201 tcagaacagg atgaaagtcg gaggataaaa agtcagttca ggtatgggga ttcagtgctt
     7261 accaccagga ccttacaatg gggacagcga atattaacgg tagccactga taaattttaa
     7321 aaaagagaat atacctaata ttcaactaaa cagtggcatc ttcaatatac tattcaaaat
     7381 atattaaagt cccccatggg gttacccgga agggcctcta tgtctgtaat tcctacttat
     7441 gtaggaaatg ttgtacagaa catttattat aatcctattc aattataata atcatgccat
     7501 tattatattt aaacaccaga gcgtgtcgtt ggtatttaat gggggaaggt gagatgaaaa
     7561 agatagctgc tatatcatta attagtattt ttcttatgtc tgggtgtgct gtacataatg
     7621 atgagacaag tatcggtaaa tttggtcttg catataaaag taatattcag cgtaaactcg
     7681 ataaccaata ctacaccgaa gccgaagctt ctttagccag gggcagaata tctggtgcag
     7741 aaaatatagt aaaaaatgat gcagcccatt tctgtgttac tcagggcaaa aaaatgcaga
     7801 tagttaaatt gaagacagaa ggtgcaggat tacatggcgt tgctcgtctg acattcaaat
     7861 gtggagagtg agaatagatt caagactacc atgcacatat ttattttatc tgtgatggga
     7921 tattcttcaa caccattatt gaatgtgagt aataatgaca aacagataga tgaaactaaa
     7981 gcagaatttt tattttatgc agccatcaga aaatgatgtc aaaaatattc caatgcttta
     8041 ggttcatttt ttggtaagcg tcaaacatgc gcgttctggc tgtgcgtaac cggaacctgt
     8101 gcgagcacga tgtcgataag tgaaaggcat cgtgctatta agggagattc tatcgatgtg
     8161 gtcaatggaa gacggtgacc agggataggg cttatgcata aaaaataagc ctgtgtaagg
     8221 gagattacac aggctaagga ggtggttcct ggtacagcta gcattttatg ggttatgttt
     8281 ttcagcgaaa cggatgataa ccttaataaa tgcagctgta tgtgatcggt ttctaagaat
     8341 tttccatccg ggaaaaataa tcgaaattaa tcacttaccg tgggggttac gcgtggtttc
     8401 cccggagaaa ttacgcatca gcagcgcgta atttagctca agatcctgcg gcaccgggag
     8461 ccacacagta taaccatcgc ctggtgcgac cggcatagct tcacctttgg cgttttccat
     8521 gtgctcaagg gtaaagttaa tgttgccttg cggcgtcatt agctcaaggc tgtcgccaac
     8581 ggagaattta tttttcaccg ctaccgccgc gaggtccccc ttgcgctcac cggtaaactc
     8641 accaacaaac tgctggcggt cagaaactga ataaccgtat tcgtagttct gataatcgtc
     8701 gtgagtatga cgacgcagga aaccttcggt atagccacga tgcgccagac cttccagagt
     8761 ttccagcagg ctggtatcga acggtttgcc cgcagcggcg tcatcgatag ctttacggta
     8821 aacctgcgcg gtgcgtgcgc aatagtagaa agatttggta cggccttcga ttttcagcga
     8881 atgcacgccc attttggtca ggcgttcaac atgggcgatg gcgcgcagat ctttcgagtt
     8941 catgatgtaa gtgccgtgct catcttcaaa cgcggtcata tactcgcccg gacgctgggc
     9001 ttcttcgatc ataaacactt tgtcggttgg cgcgccgata cccagcgtcg gctcaacatt
     9061 ttgcaccgga atcggctcgt acttgtgtac gatgttgcca acgtcatctt ctttcccttc
     9121 ctggacgttg tactcccagc ggcaggcgtt ggtgcaggtg ccctggttcg ggtcgcgctt
     9181 gttgatatag ccagagagca ggcagcgacc ggagtaggcc atgcacagcg cgccgtgaac
     9241 gaagatttcg atttccatat ccggcacctg attgcggatc tcttcaatct cttccagtga
     9301 cagttcgcga gagaggatca cgcgggtcag gcccatttgc tgccagaatt tcaccgtcgc
     9361 ccagttcacg gcgttagcct gtaccgagag atggatcggc atttcaggga agtgctcacg
     9421 caccagcata atcagccctg gatcggacat aatcagcgca tccggcccca tttccaccac
     9481 cggtttcagg tcacggataa aggttttcag cttggcgttg tgcggtgcaa tgttgaccac
     9541 gacataaaac tttttcccca gcgcgtgggc ttcgttaatg ccgagttgaa gattttcgtg
     9601 gttgaattcg ttgttgcgca cacgcaggga gtaacgcggc tggcccgcat aaacagcatc
     9661 tgcgccataa gcgaaagcgt aacgcatatt tttcagcgtt cccgccgggg aaaggagttc
     9721 cggtttaaac ataattctct cgttctgatg acaggtcaga tccgcttcac ctgatgaagc
     9781 ggtcagggga gtgcccccac tttaagggcg ggcattgtag cgctgtggag gtaactggta
     9841 aagcgccgga cgccaacaac ctacgcccgg catcgtaatt acgtattgtc tttcaccgtc
     9901 tggcttgtgc catttgcttt aacggaggca attccggttt cacgagattg cgcggtggcg
     9961 tacatctggc tggagccgat aatttgatga ttggcggctt tcagattgaa atagaatttg
    10021 ccgttgcttg ccgttttttt ctcatagcgt tcttcttgcg ggctgttgct acgtaccgac
    10081 gcgatgccct tttccgcaga ggcttttgag gtatacagct cgctggtgag gatagtctca
    10141 ccattgcccg cttttagcac aaaccggaat tgattatcac tgctcttact gagttcaaac
    10201 caaccagcca taatgactcc ttgattgaaa ttgcgtatcg aaaacagcat ctaaaaggac
    10261 tgtttgccga ttaaagtatg agcgattttc tggtgcctgc cagggcggag agatcatgtc
    10321 agtttgctga ctatgcgtgg gataatgttg ccggatctgg tctgaaggcc agatccggca
    10381 ggtaaaaatg ttaaacgatg cggcaggcgt cggcttccca gcggtaaccg acgccgtaaa
    10441 cggcgcggat aaatgactgt tcggcgtcga gagattccag cttgcggcgc aggtttttaa
    10501 tgtggctgtc gatggtacgg tcggttacca cgcggtagtc gtcataaaga tggttcagca
    10561 actgctcgcg ggagaacact tttcctggtt catgagagag cgttttcagc agtcgaaatt
    10621 ctgcaggcgt caggtcaagc attttaccgc gccaggaagc ctgaaaacga ccttcgtcga
    10681 taatcaacgg gctttcagca tcctgttgct gcaactcacg ctgcggtttg caacggcgca
    10741 aaatggtttt gacgcgcgct accacttccc gtgggctgta cggcttgcag atatagtcat
    10801 ctgcgccaat ctccaacccc agcaggcggt cgatctcttc gatttttgcc gtcaccatca
    10861 cgatcggaat gtcagaaaaa cgacgaattt cccggcacag cgtcaggcca tcggtgccag
    10921 ggagcatcag atccaacagg atcagatccg gtggtgtctg gcgcacatat ggcagtacct
    10981 gatcgccgtg gctaatcaac gttggcgcat agctcgcagc acgcagataa tcaatgagca
    11041 actgccccag cttcggttca tcttccacga tcaaaatacg cggtgtgttt tcgtcgattg
    11101 gtaactcggt catacttctc tctgtaaatc ccgttccagc ggtaactcta ctgtaatgct
    11161 aagcccgcca aaaggcgaat gggcggcaat aatgcggccg ttatgtgctt caacaatgtt
    11221 caggcaaatc gccagcccca gcccggaacc accgctggcg cggttgcggg aaccttcggt
    11281 gcgataaaaa cgttcaaaca atttttgtag ctgatcgtca ctgacacccg gcgcactgtc
    11341 ggcaaaggtc aggcgcaccg ttttgtcgtg ctgctcggca gagattttca ggctgccgcc
    11401 gctgtcagtg tagcgcaggc tgttttccag taagttattg aacaactgca ttaaacgatc
    11461 gcgatcgcca aatacggtaa tactgtctgg cagggaaaat tgcaatttca ggccacggct
    11521 ggcgaatcgt tcgcgaaatg cgcctcccgc cacttccagc agtgggatca aatctatcgg
    11581 tgctttttga taggcgagag cgccttcatc agacatagac aattgatgga gatcgtcaac
    11641 cagttttgtc agtgtaccta cttctgcctg taaagaagcc agcgtctccg gcgtgaattt
    11701 acgcacacca tcctgaatgg cttccagttc gccgcgcagt actgctaaag gcgtgcgcag
    11761 ttcatgagaa atatcggcca taaaatcgcg gcgcatctgc tggtttttct ccagtgtgct
    11821 ggcgagttga ttgaaatcct ctgccagtct gcccaactca tcttcgctgg tgggggctac
    11881 gcgagtagtg aaatcacccg ctgccagttt gtgcgtgcca tccaccagtc gttttaccgg
    11941 agccagcaaa ccgcgcgcca gtgggaatgt cgccagcgcc gctaataagg tagataaagc
    12001 cacaatcagc caactggttt gccgctgttg tctgtcaaaa ttgatatcag tattacgggt
    12061 cagtcgttca acaggggagg cgatcaccgc gccaacttcc gcaccattga ccataatggg
    12121 ccgccgtgtg ccgtcgggtg gaactggtgc tcgcgggcca accagcactt tgttgttttg
    12181 atcaaccacc caaaattgtg tgcgccagcc gtgtggcggc ataccggggc cgggcttatc
    12241 ttcgttgtta tcatgctcca gtgaacgtag gatctgaaat acaaagcgat cgttattacg
    12301 caggaagcgc cagttcccgt gctgggcgta ctgctcacca agcgcatcgc cgagcatttg
    12361 cagccgttgt tcattaccat gcttgatgta atcgataaag ccgcgctcaa aactgatacg
    12421 taccgcccag tgcatcgtga tcaataagac aatgcaggtg gcgaaaatcg ccagaaacag
    12481 tttgccggta ataccgggtc gccagaactt cattgcgcgc tcctttttcg ccgtgaaata
    12541 gccacatttt gatgcgtatc gttcggcact ctggcaaaga tgaacgccgg aagggcgatg
    12601 atagacgcca tgctaagcca ggtgtacata aagacggttt gtgtggtgcc gctgtcgacg
    12661 ctgacatgct gcgaaccaaa aagtcccagc aacagcccgg cgatggtgac gccaatactc
    12721 atcgacaatt gcataatcat cgacagcaga ctgttgccgc tgctcgccag gttgtccggg
    12781 agatctttca gcgtcagggt gttcatggag gagaaacgtg tcgagttgac cattccttgt
    12841 aaaaacagga cgaacggcaa aacgtagtac cagcccagca gagcggtagt cataaacaac
    12901 agggtgacca gcgacaggcc cagcgtggtc gccaccagta cccgacgata accaaagcga
    12961 ttcactacct gtaccacaat tcgcttcatt cccatgctgc cgagtaccat cgggatcatc
    13021 atcagtccgg catgaaacgg cgagaaaccg aggccaattt gcaggaaaac cggtgtcata
    13081 aagggcaaca tgccactgcc aatacgtccg gcaaagctcc ccgccaggcc cagcgaaaag
    13141 gtacgagtgc ggaacagttt cagactgaac agggcgcggt tgttattttg ggcgtgcagc
    13201 agataaagca ccagtgctac cacgccaact gcgaccaggc cagcaatcgc cagcggcgat
    13261 aaacctgtac ctttactgcc gtccagcgcc agggttaata ccgccatgcc aaccgccagc
    13321 aacagaaagc cggagagatc aaagcgccgc gtctgcatgg tgtagttcgg cattaacatc
    13381 agtgtggcga tcgcgccaat aattcccacc ggaatgttga tcaaaaagat ccagtgccac
    13441 gatgcgtact ccaccagcag accgccgagc gccgggccaa gcagcggccc gacctgaccg
    13501 ggcagcgtga caaaggtcat cgccgccata tattgctcgc gcggtacgat tttcatcacc
    13561 gtcaacctgc cgaccggcac catcatcgcg ccgccaacgc cctgtaacgc gcgtgccagc
    13621 aacagttcgt tcagcgtgcc ggaaagcgcg caaaacagtg aaccgagagt aaacagcacg
    13681 atggcggtaa agaaaatatt gcgcacgccg actttgtccg ccagccagcc gctggcgggc
    13741 agcatcaccg ccacggtcag tacataagag acaatgacca tgtgcatatg caacggactt
    13801 tccccgaggc tttgcgccat tgagggaagc gcggtgttaa cgatggtggt gtccagcgac
    13861 tgcataaaga agccgaaagc cacaatccac aattgccagc gggtgctgtc gggaagatct
    13921 gtcatttact cggttaccgc ttgtttaggt ttacgcgaaa aacgcatccg cagacggtcg
    13981 aaaaagagat acaccaccgg cgtggtatac agcgtcagaa gctggctcat gaccagaccg
    14041 ccgacaatgg tgatccccaa tggttgccgc aactccgagc cgtcaccgcc cgacaatacc
    14101 agcggcagcg caccaaacag cgccgccagg gtagtcatca taatcgggcg aaaacgcagc
    14161 agacaggcct ggaaaatagc ttcctgcggc gtcaggttac cgtgccgttg ggcttcaagc
    14221 gcaaaatcga ccatcataat ggcgtttttc ttcacgatgc cgattaataa catgatccct
    14281 atcagcgcaa ttaggctgaa cggggcattg aacagctcca gcgccaacag cgctccgacg
    14341 cccgccgaag gtagggtgga gagaatcgtc agtggatgca cataactctc gtaaaggata
    14401 cccagtacga tatataccgt ggcgatggcg gcgataatca ggatcacctg tgagttcatc
    14461 gtctcctgga acacctgcgc tgttccggca aaactgccgc gcaccgtcga aggcacacca
    14521 agctgggtca ttgcgcgatc gatcgccgca ctggcgtccg agagcgattt cccggtcggc
    14581 aggttgaacg aaatggtcga ggccgccgat aatccctgat gattcaccga cagtggagcg
    14641 ttcgccggtt gccatttagc gaaatacgac agcgggatcg cttttccttc gttattgata
    14701 acgaacattt tttccagtgc actgatgtcc tgggtatagc gcggatccac ttccatcacc
    14761 actttgtact ggttcatcgg ctggtaaatg gtcgagattt gccgctgacc gaaggcgtta
    14821 tttaacaggc tgttggcggc ttgcacgtca attcccaatc gcgccatggt gtcgcgatcg
    14881 taaataaggt tcatctccgc gccattatct tcctgatcgg agttaacatc agccagctct
    14941 ggcaatgtcg ccagtttttt gcggattttc ggctcccatt cgcgcagtgc cgccaggtcg
    15001 tcggataaca acgtgtactg gtaactggcg ttagcctgac gtccgccaac gcgaatatcc
    15061 tgtaccgcca tcaggaacag attcgctccc ggttctttag ccagtttttt acgcaagcga
    15121 tcgataatct gttgggccgt ttcgctccgc tcgccgcgtg gtttaagggt gataaacatc
    15181 attccactgt tcacccgtga accgccggta aagccggtga cattatccac cgccggatcg
    15241 tcacggataa ttttcatgaa gtcctgcaac ttaccgcgca tcgcctgaaa cgaaatactc
    15301 tggtcagcct gtatcccacc catcagtacg ccggtgtcct gctccgggaa gaaggttttc
    15361 gggatcgaga tatacagcca gatattcagc gcaatggtgc caagcagcac cacgcccacc
    15421 agacgggtat gattgagcac ccatttcagc gacttgccat agccttgttg cagggctacc
    15481 aacatgcgac caaagccacg cagtcgcttt tgctcgcgcg gcttgctggc ttttagcatc
    15541 cagccgcaca tcatcggcgt taacgtcagg gaaaccagca gcgaaatacc aatggcgaca
    15601 gaaagcgtca cggcaaactc gcgtaacagg cgacccggca atccgcccat caacagcagc
    15661 ggcaggaaca ccgccaccag tgacagactc atcgacagca ccgtaaagcc gacttcgcga
    15721 gtaccttgta gcgcggcctg tagcggtttc atccccgctt ccagatgacg ggcaatgttt
    15781 tccagcacca cgatggcgtc atccaccaca aagccagtgg cgatagtgag cgccattaac
    15841 gaaagattat tgagactgaa accacacagg tacatcgccg caaacgtacc aatcagcgaa
    15901 accggcaccg caacggcggg aataatggtg gcgcgacccg aacgcaggaa caaaaacacc
    15961 accagaatca ccagtgcaac tgagattacc agcgtctgct caacctcttc cagcgacgcg
    16021 cggatagtag gggagcgatc ttgggcaatt tgcagatcaa ttgctgccgg gatggtggat
    16081 tgtaattccg gcagacgggc gcggatgctg tctaccgtct ggataatatt ggcttccggc
    16141 agcttgcgga tcatcagcaa aatagccggt ttggcgttgg tcatcccggc gttgcgcaca
    16201 tcctgtactg agtcggtcac cgtcgccaca tcgcccagac gaaccgctcc gccgttgttg
    16261 taatgaataa tcagcggctg atattcagcg gcggttttca gttcatcgtt agtctggatc
    16321 tgccagcggt gagtaccatc ttccagcgcc ccctgcggtt tacgcacgtt ggcattgctg
    16381 atggcggtgc gtacgtcgtc cagcgagacg ccctgattaa acagcgcctg cggattcagc
    16441 ccgacgcgta cggcgggcag cgagctgccg ccaacatcga catcaccgac accgtcgatt
    16501 tgcgaaatcg tcggagccag ctgtgtcgag gcgaaatcgt acagttcacc ctgcgaataa
    16561 gtatcggatg tcagcgtgag gatcataatt ggcgcatccg atgggttcgc tttgcgatag
    16621 gtcggacggc tgggcatccc gctgggtagc agactttgcg cggcgttgat cgccgcctgc
    16681 acatcgcgcg ctgcgccgtt gatatcccgg tcaaaatcaa actgcaaaat aatgcgcgtg
    16741 ctgccgagcg aactgctgga ggtcatttcg ctgactccgg caatgcgccc aagtgagcgc
    16801 tccagcggcg tggcaacgga agacgccatt gtttctggtg acgcaccggg cagcgaggcg
    16861 ctgaccatga tcaccggaaa atcgacctgc ggcagcgggg cgactggcag catacggaaa
    16921 cccagtatgc cgcacagggt aatggcgacc gacagtaaaa tcgtcgccac cgggcggtaa
    16981 atgaagaggg caaaaaactt cacttacgcc tcctcttcat gacgggcaaa acggcttttg
    17041 gtccacaatg ccagacggtc gaacaacaga taaatcaccg gcgtggtaaa cagcgtcagc
    17101 acctggctga caatcagacc gccgaccatg ccgataccta acggacgacg cagttccgcg
    17161 ccgaccccgg tactcaacat cagcggcagc gcaccaagca gagccgccag agtggtcatc
    17221 aggatcggac gaaaacgcaa cagacaggcc tggtaaatag cttcgcgcgg cgacatgcct
    17281 tgctcgcgct cagcagccag cgcgaagtcg atcatcatga tggcgttctt cttcacgata
    17341 ccgatcagca aaataatgcc gataatggca atcacatcca gttcgctacc ggcaatcatt
    17401 aacgccagca gcgcgccgac ccctgcggtg ggtagcgtcg agagaatggt gatcgggtga
    17461 ataaagctct cgtacagaat gccgagcacg atatacatcg ccaccaccgc cgcgacaatc
    17521 agccagacag tgctgcccag cgccgactgg aaggcgaggg tgctgccctg gaactgcgtg
    17581 gtgatatcca ccggcagatt cagcgtcttc tctgtgtcca taatcgcctg caccgcatcg
    17641 cccagcgaat agttatccgg cacgttaaag gagatagtcg ttaccgggaa ctgatccaga
    17701 tggttgatgg aaagcggcgc aaaacgctgc tcaattttgg caattgagct taacggcacc
    17761 acgccaccgt cgctgctggt caggcgaatg gtatccagcg ccgcgaggcc tggggtattt
    17821 tcggtgttgt gttccagcac cacgcgatac tggttagcct gagtataaat agtggaaatc
    17881 agtcgctgac caaacgcgtt gtacagggcg ttatcgacat ccgccatgct gatccccaga
    17941 cggctggcgc tgtccctgtc gacattgaca tacgccacca gccctttgtc ctgccagtcg
    18001 ctggagacat cagaaagctg tggcagctgc tggagttttt ccatcaactg tggcacccag
    18061 gtactgagcg catccagtga cgtggcctgc aaggtaaact ggtactgggt gcggctgacc
    18121 tgagtatcaa tagtcaggtc ctgcgttggt tgcaggaaga gatctacgcc cggcacttta
    18181 tccaccgccg tttgcagacg ggcgatgact ttttgcaccc ggtcatctcg ttcatccagt
    18241 ggtttgagat tgatctgtaa acgcgcactg ttcagcgacg ggttagtgcc atcaacgcca
    18301 acaaatgagg tcaaactttg cactgccgga tcctgcaaaa tcacgtccgc gacctggcgt
    18361 tgccgctggg ccatattggc aaaggagctg gattgcggtg cctgcaaagt gccctgaatt
    18421 atgccgttgt cctgtaccgg gaagaaacct ttcggaatga acacccacag cagcacgcta
    18481 agcagcagcg tgctgagcgc tacgcttaag gtcagccacg gatgattcag cactttcgcc
    18541 agtccacgac cataggcggc gattatcctg tcgaacattt tctccgaggc acgggagaag
    18601 cggttctgtt tacgcagcga ctcctggctg agcatccgcg cgcacatcat cggtgtcagg
    18661 gtcagcgaca ccactgctga gatcaaaatc gcgactgcca gggtaatagc aaattcgcgg
    18721 aacagtcgcc cgacgatatc gcccataaac agcaggggga tcaataccgc aatcagcgag
    18781 aaggtcagcg agataatggt aaagccgatt tcacccgcgc ctttgagcgc ggctgccagc
    18841 ggtttttcgc ctttttcgat atagcgggaa atgttttcga tcaccacgat ggcgtcatcg
    18901 accacgaatc cggtggcgat agttaacgcc atcaacgtca ggttattgat tgaaaaatcg
    18961 agaaacacca tgaccgcaaa ggtgccaatt aacgacagcg gtacagcaac accgggaatg
    19021 atggtcgccg gaatattgcg caaaaacagg tagataatca tgactaccag cgcgatagcc
    19081 atcatcagct caaactgggt atcgtcgacc gatgcgcgga tattggtggt acggtcagaa
    19141 agtaccgtca ccttcaccga tttcggcaga ctctcggtga gctgtggtag catctgccgg
    19201 atgctgtcgg cggtggagat aatgttagca ccgggctggc gctgaacatt catcacaatg
    19261 gcctgttctt tgttcgccca cgcgccgagc cagctgtttt ctgctccttg ctctacggtt
    19321 gcgacatcgc caagacgaat tggtgcgccg ttctggtagg cgatgattag ctggcgatac
    19381 tcttcggcgg attgcatctg gtcattcgct gacagcgtga ccgcgcgaga agggccgtca
    19441 aggctccctt tcgctgagtt aacgttcgcg ccagtaatgg cggtgcgcac actttcgctg
    19501 gtcaggccga gagcggcaat tgcctgagcg ttgagtttta cgcgtaccgc cggacgctgc
    19561 ccgccggaaa gtgtcaccag ccctacgccg gaaatctgcg agattttctg cgcgacgcgg
    19621 gtttccacca tatcttccac ctgcgtcatc ggcatggcgg ttgaggtgac agcgagcgtc
    19681 atgatcggtg gatctgccgg gttcactttg ctgtaaaccg gcgggttagg cagatcgctc
    19741 ggtagcaggt tggtcgcagc gttaatcgcg gcctgcactt cctgctcggc gacatccagc
    19801 ggcaatgtta gctggaactg taaagtgata actgacgcac cgccggaact ttgcgacgac
    19861 atctgtttca ggccagacat ctgcccgaac tggcgttcga gcggcgcggt aacggcagag
    19921 gtcatgacat ccgggcttgc acctggataa agcgtgacca cctgaatggt tggatagtcc
    19981 acttccggca gcgccgaaac gggcagggcg cgataaccga taatcccggc gagtaagatc
    20041 gccaccatca gcagcgtggt ggcgacagga cgcataataa acaggcgcga cgggccgcct
    20101 gtgctgctcg ggggtaacac ctgcatcagg agcgtgctcc ttttttcgtg tcttcgcggc
    20161 tggcggcttt ttcttccgga gtagtggcgc tctgggcttc caccacttcc actttcgccc
    20221 cttcggtcag gcgatcaatt ccgtccgtca ctacgcggtc gcccgcagaa atacctgcgc
    20281 ggatcaccac tttctgactg tcctgaatgc ctggtgtcac cagatgtttg ctgaccttgt
    20341 tttcgctatt cagcacccag acaaaatggc cttcgttgcc catttgcagg gcggcggttg
    20401 ggatcaccac ggcgttttgt tcggtgtcga ctaacatgcg tgcgttaaca aactgattgg
    20461 gaaacagcgc atcatcctga ttattaaagc gtgctttcac tttaatcgta ccggtagtgg
    20521 catcgatttg gttatcaagg cttaacagtg tgccttcact taatttcttc gagttggtgc
    20581 gatcccaggc ttctaccacc agcggttttc cggctttttg cgcctgcaca acggtggcga
    20641 tatcgctttc cggcagagta aagaccagat cgataggatg tgtttgggtg atcaccacaa
    20701 tcccggtggt gtcgccactg gagatttggt taccaacatc aacctgcttg agaccaacgc
    20761 gaccatcaac tggtgcggtg atacggctcc agtcgagttg caactgcgcg ctggcgacgc
    20821 ttgcttcatc agccttaatg gtgccttcgg tttcactgac cagcgcttgt tgggcatcca
    20881 gttcctgacg agatacgaga ttggtttttg ccagttgttg ataacgcgcc aggtcacggc
    20941 gggcgttggc gagcgtggct ttatcttttg ccagttggcc ctgggcttgt gctaatgcaa
    21001 ctttgaactg gcttgggtca atttctgcca gtaaatcgcc ggctttgacc tgctggcctt
    21061 cctggaaatg taacgccatc agttgaccgt ccacgcggct gcgcaccgta acagtattag
    21121 cggcggtaat ggtgccaagc ccggtgaggt aacgtggaac agcctgttct actgcggtcg
    21181 ccgcctgaac aggagctaat gggccggcac gcataccacg gcgaccaccc gctggcgatt
    21241 gctgcgcttg tttcgtcgcc ccaggggctg cactctggga gtcattgcgg ccttgccaga
    21301 accagaatgc ggcgatggcg gcgataacca ccacgattac gattacccaa cgggatttat
    21361 aactgccttt catcgttaag agtttctctt cctgaaacgt ttcgcggaat gatactagtg
    21421 tagccagcca ataagggaga aaaatggagg aattatgaaa cactgtcggg aatcgtctga
    21481 atgacgggca cttttgcgag cacgcatcca gtaataacac atgaaactat tttatctacg
    21541 cgttagcgat agactgcttg catggcgaaa ggagataagc cgacgatttc agcgggacgc
    21601 tgaaacggga aagcccctcc cgaggaaggg gccataaata aggaaagggt catgatgaag
    21661 tggatcatca tcgtggtgct cttagtcata agcttcccgg cttactaaga ctaccagggc
    21721 gggggaaacc ccgctcaacc ctcattcctg aaagtatgcc ttcacggtcc aattgtcaat
    21781 ccgcagactt tgcagtctgc gatcctgcca gcaaatattc tttgcgagtc gttacgcaat
    21841 aatcacactt gaaactattt tatccgcaag tcagcgatag actgcataca gggcgaaagg
    21901 aggtaagccg aagatttcag cgggacgctg aaacgggaaa gcccctcccg aggaaggggc
    21961 cttaaataag gaaagggtca tgatgaagct actcatcatc gtggtgctct tagtcattag
    22021 ctacccagca tactaagact accagggcgg gggaaacccc gctctaccct cactcctgaa
    22081 attatgtcac tcaacccttg ttgtcaatct gtaagcccac gttcttgcga ggcgaatagc
    22141 aaaatcttct gcgccgccgg gcctaattct gaaagtttct tcgtttgctc ttatttcatt
    22201 attgcagtcg gtatgatacc ggacctcaat aattctctaa gaaaggattt cttatgagcg
    22261 aacaaatcac gtttgccacc agcgattttg ccagtaaccc ggaaccacgt tgcccctgca
    22321 ttttgctgct ggatgtttct ggttctatga acggtagacc cattaatgaa cttaacgccg
    22381 gattggttac ctttcgcgat gagctgcttg ccgattcgct ggccttaaaa agagtggaac
    22441 tcggcattgt gacgttcggc ccggtgcatg tggaacaacc ctttaccagc gccgctaatt
    22501 ttttcccgcc catcctgttt gcccagggcg atacaccaat gggctctgcc attaccaaag
    22561 ccctggatat ggttgaggag cggaaacgtg aatatcgtgc caatggtatt tcctattatc
    22621 gtccgtggat tttcctgatc accgatggtg caccaaccga tgagtggcag gctgccgcca
    22681 acaaagtgtt tcagggggaa gaagataaga agtttgcctt ctttaccatc ggcgttcagg
    22741 gggcggatat gaagacgctg gcacaaatca gcgttcgtca gcctttgcca ctgcagggat
    22801 tacaattccg tgaactgttt agctggttat ccagttcgct gcgttcggtt tcccgctcca
    22861 cgccgggaac ggaagttgtg ctggaagcgc caaaaggctg gacgtcagtg tgagctggcg
    22921 actggtctat gcatcagccg ttggaacgtc gcacatcagt gcggacttgc cttgccagga
    22981 tgcctgccag atacaggttg cctggctaaa tgaccagcag ccattattgt cggtatttgt
    23041 cgctgatggc gcaggtagcg cctcgcaggg aggcgaaggt gcgatgctcg ccgtcaatga
    23101 agcgatggct tatatgtcgc aaaaagtgca gggcggggaa ttggggctta atgatgtcct
    23161 cgcaacggac attgtgctga ccattcgtca gcgacttttt gccgaggcgg aagccaaaga
    23221 attagcggtt cgcgattttg cctgcacgtt tttgggattg atttcatcag ctaatggcac
    23281 cttgattatg cagattggcg atggcggcgt ggtggtagat ttgggtcacg gtttgcaact
    23341 gccgctcacg ccgatggtgg gggaatatgc caatatgacg cacttcatta ctgatgaaga
    23401 tgccgtttcc agactggata ctttcaccag cactgagcgt gcgcacaaag ttgcagcatt
    23461 tacggatggt attcagcgac tggcgttaaa tatgctggat aattctccgc atatgccttt
    23521 ctttaccccg tttttcaatg gactggcgtc agcaacgcag gaacaactcg atttattacc
    23581 tgaattgtta aagcagtttt tgtccagccc ggcggtaaac gagcgtacgg atgatgataa
    23641 aacgttggca ctggcgctgt ggttaccatg aaacccactt tatatactgc tactggtgag
    23701 tgcgttacgc caggccgtga actgggcaaa ggcggcgaag gtgcggttta tgatatcgag
    23761 gagtttgtcg agagcgtcgc caagatttat cacacgtcgc ctcccgcctt aaaacaggac
    23821 aaacttgcct ttatggctgc gacagctgac gcgcagttgt tgaattatgt cgcctggccg
    23881 caggcaacgc ttcacggtgg acgaggtgga aaagttatcg gttttatgat gccaaaagtt
    23941 tctggtaaag aaccgattca tatgatctat agcccggcac atcgtcgcca gagttaccct
    24001 cattgtgcgt gggattttct actctatgtt gcgcgcaata ttgcttcatc ttttgctacg
    24061 gttcacgagc acgggcacgt cgtgggtgac gtaaaccaga acagctttat ggtaggtcgc
    24121 gacagcaaag tggtgatgat tgatagcgac tcctttcaga ttaatgccaa tggtacactg
    24181 catttatgcg aagtcggcgt gtcgcatttt acgccgccag agctgcaaac catgccatca
    24241 tttgtcggct ttgaacgcac agaaaatcac gataattttg gccttgcgtt gctgatattt
    24301 cacgtcttgt ttggtgggcg gcatccttat tccggtgtac cgcttatctc tgatgcgggt
    24361 aatgcgctgg agacggatat tgcccatttc cgttatgcct acgcgtcaga taatcagcga
    24421 cgtggtttaa aaccgccgcc acgatcgatt ccgctgtcga tgttaccggg cgatgttgaa
    24481 gccatgtttc agcaggcatt cacggaaagt ggcgtggcaa ccgggcgtcc gacggcaaaa
    24541 gcgtgggtag cggcacttga tttactacgc caacagttaa agaaatgtac cgtttcggca
    24601 atgcatgttt atcccggtca tttggctgac tgcccatggt gtgcgctgga taatcaaggt
    24661 gttatctatt ttattgatct cggcgaagag gtcattacca ccggcgggaa ttttgtgctg
    24721 gcgaaagtct gggcgatggt gatggcgtca gtagcaccgc cagcattgca attgccatta
    24781 cccgatcatt tccaggctgc tggcaggccg cttccttcag gcctgttaag gcgcgaatac
    24841 atcattctga ttgagatcgc actgtcaggg ttatcgctgc tgctttgcgg ccttcagaca
    24901 gaaccgcgtt atatcatttt ggttcccgtg ctggcggcta tctggattat tggcagcctg
    24961 acaagcaaag cgtacaaagt agaagtccag cgacgaagag aggcttttaa tcgcgcaaaa
    25021 atggactatg accatttagt cagccagatc caacagttgg gcgggctgga aggttttatc
    25081 gccaaacggg cgatgctcga aaaaatgaag gacgaaattc ttgggttacc ggaagaagaa
    25141 aagcgcgatc tggcagcact tcacgacacc gcaagggaac ggcagaagca gaagtttctg
    25201 gagggatttt ttattgatgt tgcctctatt cccggcgttg gccctgcgcg taaagcggcg
    25261 ttacggtcct ttggtattga aacagcagcg gacgttaccc gacggagcgt taagcaagtt
    25321 aggggttttg gtgatcatct gacccaggcg gttatcgact ggaaagcgag ttgcgaacgc
    25381 cgttttgttt tcaggccgaa cgaagcggta acgcctgcag acagacaagc ggtaatggca
    25441 aaaatggccg ccaaacgaca tcggctggaa tcggcgctga ctgtcggtgc gacagagttg
    25501 cagcgattcc gccttcaagc tccagcacgg accatgccgt tgatggaacc gttacgtcag
    25561 gcggcagaaa aactggctca ggcgcaggct gatttaagcc gttgctgagc cagttttcaa
    25621 ttaacgaaac accacttccg cccagcgtgc cagcccggcg gtgacggagc caaagtcatc
    25681 gccacctgca atcggaatgc ccggcaactg ttctgtcagc gcttttttaa tcagcggtga
    25741 acgggcgcta ccgccggtca gatagataac atccggtttt tcctgggcgt tatccagcgc
    25801 cagttgcacc tgttccagaa tccgcgccag tggctggttg agggcgcttt ccagcccttg
    25861 ctggctaatc agcgtagcca gttcatcgct gataaacggc agtgaggcgc gggtttccgc
    25921 tacgcttgaa agcgcaattt tgctctcttc tgcgctacgt accaggcgat agcttaaacg
    25981 ctgacgccag actttctgta acagggccac tttttccggt tcgcgggcat cgcgtaccag
    26041 atcgttaagc agacgaccgt tggcactact gtagaaatca ctttgcgcag gtacgtcgtt
    26101 gatggcaacc gcattccacc acggcagaat cggcagggcg atgccttttt cggtttcgcc
    26161 ccccatgccc agtaacggca tcaggttctt aaacgccagt gcgatatcca gatcgttacc
    26221 accaatacgg caaccactat gacccaggag gctggcttca cgatcgagac gcgaacgcca
    26281 ttgcggcccc atcagcagca atgaacagtc agtcgtacca ccgccgatat ccactaccag
    26341 cactcgtttt tcttcctgca aggtggcttc gtaatccagc ccagccgcga ccggctcgta
    26401 ctggaatacc acatccttaa acccggcacg cttcgccgcg cgttccagaa tcccttgcgc
    26461 ctgggtgttt gcttcatcac cgcccagccc ctggaagttg atcgggcgac caatcaccgc
    26521 ctgagtaatt gcctccggca gctgcgcctg cgcctgttgg cgaatgtgca acatcattgc
    26581 gcagaccaga tcctcaaaca gcgctacctg ctgcggtttt aagccgctgg caccgaggaa
    26641 cgattttggt gatttcacaa accacacttc ttccggatca tcaatgtatt gtgccagtga
    26701 agaaagaccg aactgcacgc ttttcgccgt gacatcgata tcttcttcgc ggttataacg
    26761 aatcgcccga cgcaacagcg cctgcgtttc atcgtcgtct gccggaacat catgatggcg
    26821 gtacagccat tcgcttaccg cttcacgcgt tggcgcgcaa agcattgaag gcagcagcgt
    26881 gctgtcgttt tccattttta gcaaatgcgg tttaccgtcg cgcatgaccg ccactgaaca
    26941 gtttgctgta ccgtaatcaa aaccaataaa cacgaaataa tccccatgcc ggtgaagaag
    27001 gggcgtgact ttagcgaaat gttgccgtcg cgacaaccgg aatatgaaag caaagcgtaa
    27061 cgtctgaata acgtttatgc tgaaagcgga ttaacaagga gatgcgatgt ataccctgaa
    27121 ctggcagccg ccgtatgact ggtcgtggat gttgggattt ctcgccgccc gtgcggtgag
    27181 cggcgtggaa acggtcgcgg acagttatta tgcccgtagt ctggcggtag gcgaatatcg
    27241 cggcgtggtg actgctattc cggatatagc ccgccatact ctgcacataa atttaagtgt
    27301 aggtttagaa cctgttgccg ctgagtgtct ggcgaaaatg agccgcctgt ttgatctgca
    27361 atgtaacccg cagattgtta acggtgcgtt gggaaagtta ggcgcggggc ggcccggatt
    27421 gcgtttacct ggttgtgttg acgcttttga gcagggcgtg cgggcgattt taggccaact
    27481 ggtgagcgtg gcgatggcgg caaaattgac ctccagagtg gcacagcttt atggcgaacg
    27541 gctggatgat tttccggatt atgtctgctt ccccacgcct cagcggctgg cagtagccga
    27601 cccgcaggca ttaaaagcgt taggtatgcc gttgaaacgg gcagaggcgc tgattcatct
    27661 ggcaaatgcg gcgctggagg gcaccttacc aatgacaata ccgggcgacg tagaacaagc
    27721 gatgaaaacg ctgcaaacct ttccgggtat cgggcgctgg acggcaaatt attttgcttt
    27781 gcgtggctgg caggcgaaag atgtttttct gccggatgat tatctgatta aacagcgatt
    27841 tccgggaatg acaccggcac aaatccgccg ttatgccgaa cgctggaagc cctggcgttc
    27901 ttatgcgttg ttgcatatct ggtatacgga aggctggcaa ccagacgaag catgacgttg
    27961 gttgccggat gcggtgcgag cttatccggc ctggggaatg agcgatttgt aggcctgata
    28021 agacgcgtta gcgtcgcatc aggcaatggg caaacgctcc cttagttaat cgcgaaataa
    28081 ctgctattca ccagcaaatc cagcggttgg gcatcggcaa tcacatcgcc ataaatcaga
    28141 tcgacgccga tgccagaaag cgtatccatc actaagggta aaacgactgg cccggcgatg
    28201 gtcttcatcc cgagccgctg agcgtgcccc tgaatgatcg taatcagcat ctcatccatc
    28261 aaatttccct gcacgttggc gcataactca ccatcaagta gcaggtaatc tgccatattc
    28321 gctttcagcg agttgaagat ttgcagatcg cggcccacct gactgaatac gatccgacat
    28381 cccgccagcc gcagtttttg cacgctttct gcgtgatcta aaatcgcgtc tgccggaata
    28441 atcagatgta ataaccgtgg tgatagaggg ctattttcca gcagctcaat tagttcattc
    28501 accagcgtgg cgctactcaa accggcaacg gaaaggggga gggcgatgct taagccttta
    28561 ctggcaatcg cttttgcggc ctgctggaaa aaatcgtgga atacccgtcg gtcaagagca
    28621 tggctaagtg ccggatcgct gaagctacga cgaaatgttt gttcatcaat aatctcgcct
    28681 tcgcaactcc agagcttaag tgaaatcagc cacaaattac gcgcttgcgg gatccgcggc
    28741 gaagcgacac cgtgggcgat catcatcaac tgattctctt taatcatccg ccactgttca
    28801 tcaagcgaca tcacagcccg ttcgctatgt gcggcaactt gctgcggttc gtaaatcgtc
    28861 acccggcccc ggccaccatt tttggaggca taacaggcga tatcagcctg cgacatcact
    28921 tcagccgcct gatgattgtt gtcatcaatc aaggtaatcc ctgcactggc acctacccga
    28981 tgtacacgtc cttcccagat aaagtgatag tcattcacgg cgctgataat gcgtgtagcg
    29041 ataaaacgcg cactttcgac attacaatct ggcagcagca gaccaaattc atcgccaccg
    29101 agtcgcgcca gcacgtcgct ggagcgcagc atactcagca tcaatgacgc cagttcgcgc
    29161 agtaaagcgt cgccagcggc gtgcccggcg ctgtcattca ccgctttaaa gcgatcaaga
    29221 tcgataaaca ccagtgcatg tcgctgatgt gtactgttta ccgtttgcag caggatgcgt
    29281 agttgcttct caaaactggc tcgattggcg agatgcgtca gtgcatcatg ggaggcgctg
    29341 tagctcagct ggcgcagcat tttgcgcgat tcggtgacgt cctgaatcac cagaaccgaa
    29401 ccaatattgc tgccgtccag agtacttaac ggcgtaatac tgtaatgcac gtcgtagctg
    29461 ccgccgcttc ggcagtgcaa caccacatct tgttcaatcg cggaacgtga ggtgtcggca
    29521 ctgtaaatgt tctccattaa tggtccgttg tcgccaaaag taatatgcaa caccgtcagg
    29581 agcggaacac ctaacgcttc ttcctgcgtc cagccgctca tcttctccgc caccggattc
    29641 ataaaggtaa ttttcatcgc catatcaata cagaccacgg cttcaccgat ggaatccagc
    29701 gtaatgtgca ggcgctcttt ttcctgaaac aatgcctcgt taagctgttt aacctcggtc
    29761 atatccatat taatgccgag caggcgttcg acttcgcctt ctttattcag tacccggtta
    29821 gcgagggcgc ggatatggcg aatgccgtct ttcacggtaa tgcgaaattc cagtttaaag
    29881 ggagagcgtg attgcaatga atcgcgaatc actttttcgg cgtgctggcg atcttccggc
    29941 agcacgcact cgtaccacac ctgccagttc ggtttgatat gcggaggaat ttcatacagc
    30001 tcgaacatcc gcttatccca gctaaaaata ttcggcttta gctcccactc ccagatgcca
    30061 atcccgcccg cttcgttagc cagcgtgatg cgctccatca gttgctggtt cacctgttcg
    30121 gtgcgtttta gctcgttaat gtcttcaatc tgagcgataa aatagagcgg cgtgccatcc
    30181 gtgtggcgca ccagtgagac ggcaagcaac gcccagacaa catcgccatt gcggttgtag
    30241 tagcgttttt ccattgaata ggtgtttatt tcaccgctga tcagcttttc aacctgttgc
    30301 agatctttat tgagatcctc cggccaggtc agttgctgaa aggtgagtcc gcgcagttct
    30361 tcctgactgt aaccgagaaa ctggcagagc gctttgttgg attgcagcca ttgtccctcg
    30421 gtgcccacta atgccatgcc gatggcggaa tattccatcg cgttccgaaa gcgggtttcg
    30481 ctttcggaaa tgtgtttgcg ttccgcacga aaggcataca tcaccatggt catgatgttg
    30541 gcgggcagca ggatcagcaa aaacggtagc cacggcatat gactcatcag gtacgtacgc
    30601 ggcgtagcaa gcagagaggg atccgcggcc atcatcagcg ataccatcat cactgtggta
    30661 aggaagatca aaaaggcttc cattcgtggc aggcgcacgg cgctccacat caacagcaca
    30721 ataatgaaag taaaaggcca cggcagatac agcatcgaaa gccagcttaa cgtcagcgtg
    30781 atagctaacg tgagcagcga ctcaaaaagc aaccttgggt tgcgatggcg cagcagatag
    30841 tgtggtttaa ataacaatcc cagcggcacc agtgccagag cgccgatgga ttctgacagt
    30901 acccatatca aaaatgccct gagaggatcg tctccgggcg tcagcaggac aaccagaaca
    30961 ccccccaaca gaggcggaat aatggcgctg ccgagtgcca gacgcagcca gtcagccaga
    31021 ttttgcaagg ggttatacca cggcagcaat ttacgtagca gcactgcccc gaccacggct
    31081 tcaacaatat tgatggtcgt ccaggtcatg ttcagcgagc tggtggaaaa aagcaggatg
    31141 gatgcggcga tatttcccag cgagcagctc agcgcaattc ccggccacat gcgcccggca
    31201 tggcgataaa acgccaccat catgatggac gtcgggaacc acagtggggc gagttgggtg
    31261 ccaaactgcg aaagctcaag tgagaaaagg gtgaagataa acgagactaa acctaaactg
    31321 accaggtgaa gcagcgggtg gggcagggca attaatacat gctgtgattg tttgctcatt
    31381 accgctttat ccgcaaggcc aggtcgtcag tattcgtttc tgtgttcatg ctagtacaaa
    31441 agttttacat tttatatgcg aattgctcat aaagtgacgt aaaggcggat aatttgcgca
    31501 actgcgtata acatttttta ccttgtataa aactgatcaa cgtaatttgc caccgggaat
    31561 tcttcgtcaa caattaactc tgagcgcgcg gcaacgctat tcgactggta tcaggcggat
    31621 gaaatcccta taattgccgc gtttggcgct tcgtcgcccc cttcctaaca tccaggttaa
    31681 tcaggtcgct aaatatatga ctgatcagtc tcatcagtgc gtcattatcg gtatcgctgg
    31741 cgcatcggct tccggcaaga gtcttattgc cagtaccctt tatcgtgaat tacgtgagca
    31801 agtcggtgat gaacacatcg gcgtaattcc cgaagactgc tattacaaag atcaaagcca
    31861 tctgtcgatg gaagaacgcg ttaagaccaa ctacgaccat cccagcgcga tggatcacag
    31921 cctgctgctt gagcatttac aagcgttgaa acgcggctcg gcaattgacc tgccggttta
    31981 cagctatgtt gaacatacgc gtatgaaaga aacggtgacg gttgagccga agaaggtcat
    32041 cattctcgaa ggcattttgt tgctgacgga tgcgcgttta cgtgacgaac ttaacttctc
    32101 cattttcgtt gataccccgc tggatatctg tctgatgcgc cgcatcaagc gtgacgttaa
    32161 cgagcgtggg cgttcaatgg attcagtgat ggcgcaatat caaaaaaccg tgcgcccgat
    32221 gttcctgcaa ttcattgagc cttctaaaca atatgcggac attatcgtgc cgcgcggcgg
    32281 gaaaaaccgc atcgcgatcg atatattgaa agcgaaaata agtcagttct ttgaataagc
    32341 ttgataaatt gtgtaccgtt cagtgataac ctggtatgcc cttgacgtaa ttggcgttaa
    32401 gggagtgatg ctcgaaagga gaaaatgcca tgcgtctgtg tgaccgagat attgaagcct
    32461 ggcttgatga aggccgtttg tcgatcaacc cacgtccgcc agtggagcgt attaacggcg
    32521 cgacggtgga tgtgcgcctg ggcaataaat ttcgtacctt ccgtggtcac acggcagcgt
    32581 ttatcgatct gagcggtccc aaagatgaag tgagcgccgc gcttgaccgc gtgatgagcg
    32641 atgaaatcgt gctcgacgag ggcgaggcgt tttatcttca cccaggagag ctggcgctgg
    32701 cggtgacgct ggagtcggtg acgctgccag ccgatctggt gggctggctg gacgggcgtt
    32761 cttcactggc gcgtctgggg ctgatggtgc acgtcaccgc gcaccgtatc gatccgggct
    32821 ggtctggctg cattgtgctg gagttttaca actccggtaa gctgccgctg gcgctgcgtc
    32881 cgggcatgtt aattggtgcg ctgagctttg agccgctctc cggcccggcg gcgcgacctt
    32941 acaaccgccg tgaagatgcg aaatatcgca accagcaggg cgcggtagcc agccgaatcg
    33001 ataaagacta attcaggccc attgaggata ccatgagacg atttctgacg acgctgatga
    33061 tactcctggt cgtgctggtg gccgggttat ctgcgttagt gttgctggtg aatccgaatg
    33121 atttccgcga ctatatggtc aagcaagttg ctgcacgtag cggttatcaa ttgcagctcg
    33181 acgggccact gcgttggcac gtctggccgc agcttagtat cctctccggg cgaatgtctc
    33241 tcaccgccca gggcgcaagc cagccactgg ttcgcgccga caacatgcgt ctggacgtgg
    33301 cgcttttacc actactgagt catcaactga gcgttaagca ggtgatgcta aaaggggcag
    33361 tgatccaact gacgccgcag acggaagcgg tgcgcagtga agacgctccg gttgcaccgc
    33421 gcgacaatac cttgccggat ctgtcagacg atcgcggatg gtcgtttgat atatccagtc
    33481 ttaaggtggc ggacagcgtt ctggtgttcc agcatgaaga tgacgagcag gtgacaatcc
    33541 gcaatatccg cctgcaaatg gaacaagatc cccaacatcg tggctcattt gagttttccg
    33601 ggcgggttaa tcgcgatcag cgcgatctca cattatccct taacggtaca gtagatgctt
    33661 ctgattatcc gcatgattta acggcggcta ttgaacaaat taactggcag ttgcaggggg
    33721 ccgatttacc aaaacaaggt attcaggggc aggggagttt ccaggcccag tggcaggagt
    33781 cacataaacg cctttcattt aaccaaatca gtttgaccgc caatgacagt acgctgagcg
    33841 ggcaagcaca ggtcacgttg acagagaaac cggaatggca gctgagactg caattcccgc
    33901 aactgaatct tgacaacctc atccccctta atgaaacagc gaacggtgag aacggtgccg
    33961 cgcagcaagg gcagagccaa tcaacgttgc cgcgcccggt catttcttcg cgtattgatg
    34021 aaccggccta tcagggactg caaggcttta cggctgatat tttgttgcag gccagtaacg
    34081 tgcgctggcg cggaatgaat tttacagatg ttgccacgca aatgaccaac aagtcgggtt
    34141 tgctggaaat tactcaactg cagggcaaac ttaacggtgg acaggtttca ctgccgggca
    34201 cgttggacgc gacatcaata aatccgcgga taaacttcca gccacggctg gaaaacgttg
    34261 agattggcac cattctgaag gcgtttaact atccgatttc gttgaccgga aagatgtcac
    34321 tggctggtga tttctccggt gctgacatag atgccgacgc attccgccac aactggcaag
    34381 gacaggcaca tgtcgaaatg actgatacac gcatggaagg gatgaacttc cagcagatga
    34441 ttcagcaagc ggtagaacgt aatggtggtg atgtgaaggc cgctgaaaac ttcgataacg
    34501 tgacgcgtct tgaccgcttt accaccgatt tgacgttgaa ggatggcgtc gtgacgttaa
    34561 acgacatgca aggtcaatcg cctgtgctgg cgctgacagg ggaaggcatg ttgaatctgg
    34621 cagatcaaac ctgcgacacc cagtttgata ttcgggtcgt gggtggctgg aacggggaaa
    34681 gcaaactgat tgatttcctc aaagaaacgc cagtaccgct gcgggtttat ggcaactggc
    34741 agcaacttaa ttacagcctg caagtggatc agttactgcg taaacatcta caggatgaag
    34801 caaaacgccg tcttaacgac tgggccgagc ggaataaaga ttcccgcaat ggcaaagatg
    34861 tgaagaagtt gctggagaag atgtaggtta ccaggtgacc tgtcctgtag gcctgataag
    34921 acgcgtaaag cgtcgcatca ggcgttcgtg gcggcaccat tatattctga atatgtaaga
    34981 tcgaaggctg ttccgttcac ttgatgttcc tcgctactat ggaacgctca agccggtgaa
    35041 cgtgccaggg tggctcaatc gccaccaccc tggcaacccg ggctcccggc ggtaaatcgc
    35101 cgctggcgcg gttccctcat cttattcctt tcggctatcg ggtacgggcg cgaggtaaca
    35161 tccctgtaaa acgcgccctc agcccacatc catgtgggct gccccggcct acaggaaacg
    35221 attcggcgat ttacagccgg acccacaccc ccgctgtgat gtccatgtac cacagacaac
    35281 gcttcattgc tgaagttata aggcgttacg cagcattggg taaaatggcc gatgccatca
    35341 cacctcgtac tccatctcgc catccttacg cagcggaata atctgcacct tctgcacgcg
    35401 atggctttcc acctgcaacg ttttaagcaa ataatccccc acctgaactt cttcgccagg
    35461 ttttggaata cgttgcaaat attccatcaa tagcccggca atggtgtgat attcacgttt
    35521 ttcatccagc ggcaacggca catattgcac cagatcttcc agcggcatat gaccattcgc
    35581 cgtccaggaa ccgtccgcat tcttctgaat atcatggcgg gcgtcgatct cttccacttc
    35641 gttcggtaag ttaccggcaa tggtttcagt gacgtcactt aatgtcacaa tcccttccac
    35701 cgagccaaac tcatccacca caaaagcaaa gtgtgtgcgg gcattacgga actgctccag
    35761 ggcaggtaac aacggcaagg tttccgggaa caccagcggc tggcgaatca acacccgcag
    35821 gttgagcggt tcgccgcgca gtgactgttg tagcaggtcg ataacgtgaa caacaccgag
    35881 caaatcttct gcgtcatcgc catcagtaac gacaagccgc gtatgctgat ttcgctccag
    35941 taactggcgg atctcgtctt ccggcgcgtt gagatcgata tgctcaatat cgtggcgcga
    36001 cgtcataatg ctgctgacgg tacgctggtt aagattaagt acccgctcaa tcatccgccg
    36061 ttcctgcgga ttaaagattt gctggttacc atgatccacc agcatagacg cggtttcggc
    36121 gtccagttcc gcatcttctt tttgcccact aagcaggcgc attaccgctt cggtagtccg
    36181 ctggcgcagc gtctgattag cggaaagaaa acgtcgccgg ttaaagatag ccaactgatt
    36241 gagcgcctcg atcatcaccg agaaaccaat agcagcgtac aggtagcctt tcggaatgac
    36301 gaagccgaaa ccttctgcca ccaggctaaa gccaatcatc aacaggaagc ttaggcagag
    36361 aataacgatg gtcgggtgac tgttaacaaa ttgcgttaac ggcttgctgg ccatcaacat
    36421 caggctgata gcgataacca cggcggccat catgaccagt aaatggtcga ccatcccgac
    36481 ggcggtaatc accgagtcga gtgagaagat ggcgtccagt accacaattt gtgtcaccac
    36541 cccccagaac ttcgcacctt tgcgttgcgt ggggttattg ctgtctttcc cttccagccg
    36601 ttcgttcagc tccatcgtgg ctttgaacag caggaagaaa ccaccaaaca gcatgattaa
    36661 atcgcgggcg ctaaaggtaa acgagcggaa gctgaacagc ggttgagtca gggtgaccag
    36721 ccaggagatt gacgccagca gtaacaggcg cattaacatc gccagcagca gcccggtaac
    36781 ccgtgcgcgg tcgcgctgct tcggcggcag tttttcggcg aggatggcaa taaagaccag
    36841 gttatcaatg ccgaggacca gttcgatcac aatcagcgtg attaacccag cccagataga
    36901 cggatcggca atccattcca tagtaagtac aaaacctatt cgttgtatga caaatgtcac
    36961 aattcgatca tggataaatc ggggcaaaaa tgcaatgttg cagcactatt tatctcatat
    37021 tatttgaggg ttataacctc acattatccc agaattaaag gtgctaataa taaaacatta
    37081 tttaagaaat atcgcatgtg gagacactat attaaatatt gtcaatctaa agaaactcct
    37141 aaaaaccata ttgaacgaca cttaatataa ttcttaaaaa tagccaattg ccgaattgtt
    37201 accttgcctg ctattccgtt agctgtaaca cttcctcctg cattattgga gagccaatat
    37261 tcaattacca taatgtcacc ttatattcgg aagttaattt ccgcaataac cctttctcat
    37321 caacgactgt atgcagagag ggtgtgaaaa attaagctaa attagtgtgt tggtagctaa
    37381 aaggccaggg gcggtagcgt gtctggatgc ctgaaagacc agtctgaatt attctgtcaa
    37441 tagcctgcgg atgaaatcaa ttttttttag gactgatgcc agttaaattt ttattcaatt
    37501 aactgcaagg taaatgtgca tggcgacatt gctattaata gtgcacagga taattactct
    37561 gccaaagtga taaataaaca atgatgaaat ccaaaatgaa attgatgcca ttattggtgt
    37621 cagtaacctt gataagcggt tgcacagtac ttccgggcag caatatgtcg acgctgggga
    37681 aagacgtcat caaacagcag gacgctgatt tcgatctcga caaaatggtg aatgtttatc
    37741 cgctgacccc gcgcctgatt gatcaattac gcccacgccc gaatgtagcg cgccccaata
    37801 tgacgctgga aagcgagatc gcgaattacc agtatcgcgt cgggccgggg gacgttctta
    37861 atgtcaccgt ctgggatcac ccggaactca ccacgccagc cggtcagtac cgcagctcca
    37921 gcgacaccgg caactgggta cagcctgacg gcaccatgtt ctacccgtat atcggcaaag
    37981 ttcacgtggt ggggaaaacg ctcgctgaaa tccgcagtga tattaccggg cgcttagcga
    38041 cgtacatcgc tgacccgcag gtggacgtta atatcgccgc cttccgctcg caaaaagcct
    38101 atatctccgg tcaggtgaat aaatccggtc aacaggccat taccaacgtg ccactgacca
    38161 ttctcgacgc catcaacgcc gcaggtggcc tgaccgacac cgctgactgg cgcaacgtgg
    38221 tgctaacaca caatggtcgt gaagagcgca tttctttgca ggcgctgatg caaaacggcg
    38281 acctcaatca gaaccgactg ctttaccccg gcgatattct ttacgtgcca cgtaatgatg
    38341 atctgaaagt gtttgtgatg ggtgaagtga agaaacagag caccctgaaa atggacttta
    38401 gcggcatgac cctgactgaa gccctgggca atgctgaagg catcgacatg accacctcca
    38461 acgccagcgg catctttgtc attcgtccgc tgaaaggcga gagcgggcgt aacggcaaga
    38521 ttgccaatat ctaccagctg gatatgtccg atgcgacgtc gctggtaatg gcgacagaat
    38581 tccgcctgca accttatgac gtggtgtatg tcaccaccgc cccggtatcc cgctggaacc
    38641 gtctgatcaa tcagttgctg ccaactatta gcggtgtccg ttacatgacg gatacagcca
    38701 gcgacattca taactggtaa tcgtcatgtt taacaacatc ttagttgtct gtgtcggcaa
    38761 tatttgccgt tccccgacgg cggaacgctt actgcaacgt tatcacccgg agctaaaagt
    38821 ggagtccgct ggactcggcg cgttggtcgg taagggcgct gatcctaccg ctatcagcgt
    38881 cgccgcagaa catcaactgt ccctggaagg tcactgtgca cggcaaatca gccgccgcct
    38941 gtgtcgcaac tacgacctga ttctgaccat ggaaaagcgc catatcgaac gcttatgcga
    39001 gatggcaccc gagatgcgcg gcaaagtgat gctgtttggt cactgggata acgaatgtga
    39061 aatccccgat ccatatcgca aaagccggga aacgtttgca gcggtgtacg cattacttga
    39121 acggtctgcc caccagtggg cgcaggcatt gaacgcagag caggtataag aatgacagaa
    39181 aaagtaaaac aacatgccgc tccggtaacg ggcagtgatg aaatcgatat tggtcgcctg
    39241 gttggcacca tcattgaagc acgctggtgg gtgattggca ttaccgccgt attcgccctc
    39301 tgtgccgtgg tttacacctt cttcgctacg ccgatataca gcgccgacgc actggtacaa
    39361 atcgaacaaa gcagcggcaa ttcgttagtg caggatatcg gatcggcatt agccaacaaa
    39421 ccgcctgcat cggacgccga gatccagttg attcgttcgc gtctggtgct tggtaaaacg
    39481 gtggacgatc tcgaccttga tattgcggtg agcaaaaaca cgttcccgat tttcggtgcg
    39541 ggctgggagc gcctgacggg acgccagaac gagacggtga aagtgaccac ctttaaccga
    39601 ccgaaggaga tggcggatca ggtgtttacg cttaatgtgc tggacaacaa aaactacacc
    39661 ctgagcagcg atggcggctt tagcgcccgt gggcaagcgg gccagatgct gaaaaaagaa
    39721 ggcgtcacgc tgatggttga agccattcac gccagcccgg gcagtgagtt taccgtcacc
    39781 aaatactcca cgctggggat gatcaaccaa ctgcaaaaca gcctgacggt aacggagaac
    39841 ggcaaagacg caggtgttct gagcctgact tacaccggtg aagatcgcga acagatccgc
    39901 gacattctta acagcatcgc ccgtaactat caggaacaaa atattgagcg caaatcggcg
    39961 gaagcgtcga aaagcctcgc tttcctcgcg caacagttac cggaagtacg tagccgcctt
    40021 gatgttgccg aaaacaaact gaatgccttc cgtcaggata aagattcagt tgatctgccg
    40081 ctggaagcga aagcggtgct cgattcgatg gtgaacatcg acgcgcagtt gaacgaactg
    40141 acctttaaag aggcggaaat ctccaagctg tacaccaaag ttcacccggc gtaccgcacg
    40201 ctgctggaga aacggcaggc gctggaagac gaaaaagcca aacttaatgg tcgcgtaacg
    40261 gcgatgccga aaacccagca ggaaattgtg cgtctgaccc gcgatgtcga gtctggtcag
    40321 caggtctata tgcaactgct gaataaagag caggagctga aaatcaccga agccagcacc
    40381 gtcggcgatg tgcgcattgt cgacccggca atcacccagc caggtgtact gaaaccgaag
    40441 aaagtgctga ttatccttgg ggcgattatc cttggcctga tgctctctat cgtgggtgtg
    40501 ctgctgcgct cgttgtttaa tcgcggtatc gaaagcccgc aggtgctgga agaacacggt
    40561 atcagcgttt atgccagcat cccgctgtcg gagtggcaga aagcgcgcga tagcgtcaaa
    40621 accatcaaag ggattaaacg ctataaacag agccagctac tggcggtggg gaatccaacc
    40681 gatctggcga ttgaagccat ccgtagtctg cgtaccagtc tgcacttcgc gatgatgcag
    40741 gcacagaaca atgtgttgat gatgaccggg gttagcccgt caatcggtaa aacctttgtc
    40801 tgcgccaacc tggcggcggt gattagccag accaataaac gggtgttgtt gatcgactgc
    40861 gatatgcgca aaggctacac ccacgagctg ttgggcacta ataacgttaa tggcctgtcg
    40921 gaaattctga ttggacaggg cgatattact accgctgcta aaccgacctc tattgccaaa
    40981 tttgacctga tcccgcgcgg tcaggtaccg ccaaatcctt ctgaactgtt aatgagcgaa
    41041 cgctttgccg aactggtgaa gtgggcgagt aaaaactacg acctggtgtt gattgatacg
    41101 ccgccgattc tggcagtgac cgatgcggca attgttggtc gtcatgtcgg aaccacgttg
    41161 atggtggcgc gttatgcggt caacacattg aaagaagtgg aaaccagtct gagccgcttt
    41221 gagcaaaacg gtattccggt gaaaggggtg attctgaact ccatcttccg ccgcgccagc
    41281 gcgtatcagg attatggcta ttacgaatac gaatataagt cggatgcgaa ataacgagat
    41341 ccgctgtcgg atgcgatgct gacgcatctt atccgaccta cgttcacgcc gcatccggca
    41401 acagaacctg taaaccagct tataaaccgg cagaacatct cgatactccg ggagaacaac
    41461 ctatgaaaga caatccgctg atttcaatct atatgccgac ctggaaccgc caacaactgg
    41521 cgattcgggc gataaaatcg gtcctgcgcc aggactacaa caactgggag atgatcatcg
    41581 tggatgattg ctccacctcc tgggaacaac tacaacagta cgtcaccgcc ctcaacgatc
    41641 cgcgtatcac ttacattcac aacgacatta acagcggggc gtgcgcggta cgtaaccagg
    41701 cgattatgct ggcgcaaggg gaatacatca ccgggatcga tgacgatgat gaatggacac
    41761 ccaaccgcct gagcgtcttc ctcgcccata aacagcaact ggtcacacac gcctttttgt
    41821 acgctaacga ctacgtttgc cagggcgaag tttattccca accggcaagc ttgccgctgt
    41881 atcccaaatc gccgtattca cgccgcctgt tttacaaacg caatatcatt ggcaatcagg
    41941 tctttacctg ggcgtggcgt ttcaaagagt gcttgttcga taccgaactg aaagcggcac
    42001 aggattacga catcttcctg cggatggtgg tggagtacgg cgaaccgtgg aaagtggaag
    42061 aggcgacgca gatcctgcat atcaatcacg gcgaaatgca gatcacctcg tcaccgaaaa
    42121 aattctccgg atacttccac ttttaccgca agcacaaaga caaattcgac cgcgccagca
    42181 aaaaatatca gctgtttacc ctctaccaga tccgcaataa acgcatgacc tggcgcactt
    42241 tgctgacgct gctgtcggtg cgtaacggca aacgtctggc tgatggtatt cgggggcgct
    42301 aaagatgctg gaagatctgc gcgccaacag ctggagttta cgcccgtgct gcatggttct
    42361 tgcctatcgt gccgctcatt tttgttcggt gtggcgcaaa aagaacgtcc tcaacaatct
    42421 ttgggcggcc ccgctgctgg tgctgtatcg cattatcacc gaatgctttt tcggttatga
    42481 aatccaggcc gccgcgacca taggccgacg ctttactatc catcacggtt acgccgtagt
    42541 gatcaataaa aacgtggtcg cgggggatga tttcaccatt cgtcacggcg tcactatcgg
    42601 caatcgtggc gccgataaca tggcatgtcc acacattggc aacggcgtcg aactcggtgc
    42661 caacgtcatt attcttggtg atatcacgat tggtaacaac gtcaccgtgg gcgcgggcag
    42721 cgtggtgctc gactctgtcc cggacaacgc gctggtggtg ggagaaaaag cgcgagtgaa
    42781 ggtaattaaa tgaatattct gcaatttaat gtgcgactgg cggaaggcgg ggcagcaggt
    42841 gtggcattag atctccacca gcgcgcgctg caacaggggc tggcgtcaca ttttgtctac
    42901 ggctacggca aaggcggcaa agagagcgtc agccatcaga actatccgca ggtcatcaaa
    42961 catacgccac ggatgaccgc gatggcgaac attgcgttgt ttcgtctgct taatcgcgat
    43021 ctgttcggca atttcaatga gttatatcgc accattactc gcacaccggg cccggtggtt
    43081 ctgcattttc atgtgctgca cagctactgg ttgaatctta agagcgtggt gcgcttttgc
    43141 gaaaaagtga aaaaccataa accggatgtc actctggtct ggacgctaca cgaccactgg
    43201 agcgttaccg gacgctgcgc ctttaccgac ggttgcgaag gctggaaaac gggctgccag
    43261 aaatgcccga ccttaaataa ctatccaccg gtgaagattg atcgcgcgca ccagctggtg
    43321 gcgggtaaac gccagttatt ccgcgagatg ctggcactgg gctgtcagtt tatttccccc
    43381 agccagcatg tggctgatgc tttcaatagt ctgtacggtc cagggcgttg ccggattatc
    43441 aataatggca ttgatatggc aaccgaagcg attctggcgg acttgcctcc ggtacgcgaa
    43501 acccagggca agccgaaaat cgcggtggtg gcgcatgacc tgcgttacga cggcaaaact
    43561 aaccagcaac tggtacgcga gatgatggcg ctgggtgaca aaatcgaact gcataccttt
    43621 ggtaagttct cgccgttcac cgctggtaac gttgtcaatc acggctttga aactgacaag
    43681 cgcaagttaa tgagcgtgct caatcagatg gatgcgctgg tgttcagttc tcgcgtcgat
    43741 aactacccgc tgattttgtg tgaggcgtta tcgattggcg tgccggtgat cgccacccat
    43801 agcgatgcgg cgcgggaagt gctgcaaaaa tccggtggta aaaccgtcag cgaagaagat
    43861 gtgctgcaac tggtgcagtt aagcaaaccg gaaatcgcac aggcgatatt tggtaccacg
    43921 ctggctgaat tcagccagcg cagccgcgcc gcctacagtg gacaacagat gctggaggag
    43981 tatgtcaact tctatcagaa tctgtagcta cctgctgctg ccgctgatct acctgctggt
    44041 taacgtcaaa atcgcccagc ttggcgaaag tttccccatc accatcgtca cttttttacc
    44101 tgtcctgtta ctgctgtttt tagagcgcat cagcgttaaa aaattgatga ttgccttggg
    44161 gattggcgcg ggacttacgg cgtttaacta cctgtttggt cagtcgctgg atgccagtaa
    44221 atacgtcact tcaaccatgc tgtttgtcta tattgtgatc attattggca tggtgtggag
    44281 tattcgcttt aaaacgattt cgccacacaa ccatcgcaag atattacgtt tcttttatct
    44341 ggtggtcggg ctggtggtgg tgctggcggc ggtggagatg gcgcaaatta tcctcaccgg
    44401 cggtagcagt attatggagt cgatttcgaa atatctgatt tacagcaaca gctatgtgct
    44461 gaatttcatt aaattcggcg gcaagcgcac gacagcactt tatttcgaac cggcattttt
    44521 cgctctggca ttaatctcaa tttggctcag catcaaacag tttggtatca aaacgcctaa
    44581 aacagatgct atgattctcg cagggataat attatccggt tcattttcag gggttatgac
    44641 ctttatcctt ttttatttgc tggagtgggc atttcaatat ctgaataaag aggcgattaa
    44701 gaaaaagtta ccgttagcat tgatttctct ggctgtattc ctggttggtg tggtaatcgc
    44761 gttcccttat atttccaccc gtctgggcga tttaggtaca gaaggatcgt catcgtatta
    44821 tcgtattgtc ggtccgctgg tgatggtcgg ttattcttta acccatattg acggtgtagt
    44881 cagatttggc tcactttatg aatatgtcgc atcattcgga atatttaacg gtgcggatgt
    44941 cggaaaaacc atagacaatg gtttgtatct gctgattatt tatttttcct ggttcgcagt
    45001 gtttttatcg ctgtggtaca tgggaaaagt gataaaaatg atgatcaacg cttttggtga
    45061 taaccgcaat tttcgcgtgc aattatatct ttttactccg gtatcgctgt tttttaccgg
    45121 ttcgatattt agcccagaat atgcgttttt aatcgtctgc ccgtttattt tgcgaaaagc
    45181 gttaaatata caccctaaat aattcgagtt gcaggaagtg ggtgagcgag gaaaaccaac
    45241 gcacatgcag cttgaagtat gacgggtatt acgaggtaaa acatgttgct tagcataatc
    45301 actgtcgcgt ttcgtaacct cgaaggaata gtcaaaacac acgcctcgct ggcgcatctg
    45361 gcgcaggcgg acgatatcag cttcgaatgg attgttgttg atggcggttc caacgacggc
    45421 acccgtgagt atctggaaaa tctcaatggt atctataact tacactttgt cagcgaacca
    45481 gataacggta tctacgacgc catgaacaaa ggtattgaaa tggcgcaagg caagttcgcg
    45541 ttgtttctca actcgggcga tatttttcat caggatgccg catattttgt ccgtaagtta
    45601 aaagtgcaaa aagataacgt gatgatcacc ggcgatgcgc tgctggattt tggcgacggg
    45661 cataaaatta aacgtagcgc caaaccgggt tggtatattt accacagcct gcccgccagt
    45721 catcaggcga tatttttccc ggtgtccggc ttgaagaaat ggcgttatga cctggagtat
    45781 aaagtttctt ccgattacgc gctggcggcc aaaatgtata aagccggtta tgcatttaaa
    45841 aaactcaatg gcctggtgtc tgaattttct atgggtgggg tatctaccac caataatatg
    45901 gaattgtgtg ctgacgccaa aaaagtccaa cggcaaatat tgcacgtgcc tggcttttgg
    45961 gctgaattat cctggcattt acgccaacgt acgacctcaa agacgaaagc cttatataac
    46021 aaaagctgaa tataagggaa aacgatgcag gatttaagtg gattctcggt gccgaaaggg
    46081 ttccggggtg gcaacgctat taaagtgcaa ttgtggtggg cagtacaggc aacaatattt
    46141 gcctggtcgc cacaagtatt gtatcgctgg cgggcatttt tattacgttt attcggcgca
    46201 aaaataggaa aaaacgtagt cattcgtccg tcagtaaaaa ttacctatcc gtggaaatta
    46261 acgttaggtg attacgcgtg ggtcggcgat gaggtcaatt tatataccct cggtgaaata
    46321 accattggcg cacattcggt gatatcgcaa aaaagttatt tatgcactgg tagccacgac
    46381 catgcaagtc aacatttcac cattaacgcc acgcctattg tgattggcga gaaatgctgg
    46441 ctggcaaccg atgtctttgt tgcccctggc gtcacgatcg gcgacggcac cgtcgtgggt
    46501 gcgcgaagca gtgtttttaa atcgcttccg gcaaatgtgg tttgtcgggg gcaccccgca
    46561 gtggtgatac gcaaacgcgt tgaaactgaa taaattcaaa aaatacagag gaataagaca
    46621 tgtcaaaagt cgctctcatc accggtgtaa ccggacaaga cggttcttac ctggcagagt
    46681 ttctgctgga aaaaggttac gaggtgcatg gtattaagcg tcgtgcatcg tcattcaaca
    46741 ccgagcgcgt ggatcacatt tatcaggatc cgcacacctg caacccgaaa ttccatctgc
    46801 attatggcga cctgagtgat acctccaacc tgacgcgcat tttgcgtgaa gtgcagccgg
    46861 atgaagtgta caacctgggg gcaatgagcc acgttgcggt ttcttttgag tcaccggaat
    46921 ataccgcaga cgtcgatgcg atgggtacgc tgcgcctgct cgaggcgatc cgcttcctcg
    46981 gtctggaaaa gaaaacccgt ttctatcagg cttctacttc tgaactgtac ggtctggtgc
    47041 aggaaattcc gcagaaagag accacgccgt tctacccgcg atctccgtat gcggttgcca
    47101 aactgtacgc ctactggatc accgttaact accgcgaatc ctacggcatg tacgcctgta
    47161 acggtattct cttcaaccat gaatccccgc gccgtggcga gactttcgtt acccgcaaaa
    47221 tcacccgcgc aatcgccaac atcgcccagg ggctggagtc gtgcctgtat ctcggcaata
    47281 tggattccct gcgtgactgg ggccacgcca aagactacgt aaaaatgcag tggatgatgc
    47341 tgcaacagga acaaccggaa gatttcgtta ttgccaccgg cgttcagtac tccgtgcgtc
    47401 agttcgtgga aatggcggcg gcacaactgg gcatcaaact gcgctttgaa ggcacgggtg
    47461 ttgaagagaa gggcattgtg gtttccgtca ccgggcatga cgcgccgggc gttaaaccgg
    47521 gtgatgtgat tatcgccgtt gacccgcgct acttccgtcc ggcagaagtt gaaacgctgc
    47581 tcggtgaccc gaccaaagcg cacgaaaaac tgggctggaa accggaaatc accctcagag
    47641 agatggtgtc tgaaatggtg gctaatgacc ttgaagcggc gaaaaaacac tctctgctga
    47701 aatctcacgg ctacgacgtg gcgatcgcgc tggagtcata agcatgagta aacaacgcat
    47761 ttttattgct ggccatcgcg ggatggtcgg ttccgccatc aggcggcagc tcgaacagcg
    47821 cggtgatgtg gagctggtat tacgcacccg cgatgaactg aacctgctgg acagccgcgc
    47881 ggtgcatgat ttctttgcca gcgaaagcat tgaccaggtc tatctggcgg cggcgaaagt
    47941 gggtggtatt gttgccaaca acacgtatcc ggcagatttc atctaccaga acatgatgat
    48001 tgagagcaac atcattcacg ccgcgcatca gaacgacgtg aacaaactgc tgtttctcgg
    48061 atcgtcctgc atctacccga aactggcaaa acagccgatg gcagaaagcg agttgttgca
    48121 gggcacgctg gagccgacca acgagcctta cgccattgcc aaaatcgccg ggatcaaact
    48181 gtgtgaatct tacaatcgcc agtacggacg ggattaccgc tcagtcatgc caaccaacct
    48241 gtacgggcca cacgacaact tccacccgag taattcgcat gtgatcccag cattgctgcg
    48301 tcgcttccat gaggcgacgg cacagaatgc gccggacgtg gtggtgtggg gcagcggtac
    48361 gccgatgcgc gaatttctac acgttgatga tatggcagcg gcgagcattc atgtcatgga
    48421 gctggcacac gaagtctggc aggagaacac ccagccgatg ctgtcgcaca ttaacgtcgg
    48481 cacgggcgtt gactgcacta tccgtgagct ggcgcaaacc atcgccaaag tggtgggtta
    48541 caaaggtcgg gtggtttttg atgccagcaa accggatggc acgccgcgca aactgctgga
    48601 tgtgacgcgg ctgcatcagc ttggctggta tcacgaaatc tcactggaag cggggcttgc
    48661 cagcacttac cagtggttcc ttgagaatca agaccgcttt cgggggtaat gatgttttta
    48721 cgtcaggaag actttgccac ggtagtgcgc tccactccgc ttgtctctct cgactttatt
    48781 gtcgagaaca gtcgcggcga gtttctgctt ggcaaaagaa ccaaccgccc ggcgcagggt
    48841 tactggtttg tgccgggagg gcgcgtgcag aaagacgaaa cgctggaagc cgcatttgag
    48901 cggctgacga tggcggaact ggggttgcgt ctgccgataa cagcaggcca gttttacggt
    48961 gtctggcagc acttttatga cgataacttc tccggctcgg attttaccac tcactatgtg
    49021 gtgctcggtt ttcgcttcag agtagcggag gaagagctgt tactgccgga tgagcagcat
    49081 gacgattacc gctggctgac gccggacgcg ttgctcgcca gtgacaatgt tcacgctaac
    49141 agccgcgcct attttctcgc tgagaagcgt gccggagtac ccggattatg aaaatactgg
    49201 tctacggcat taactactcg ccggagttaa ccggcatcgg caaatacacc ggcgagatgg
    49261 tggaatggct ggcggcacaa ggtcatgagg tgcgggtcat taccgcgccg ccttactacc
    49321 cgcagtggca ggtgggcgag aactattccg cctggcggta caaacgggaa gagggggccg
    49381 ccatggtgtg gcgctgcccg ctgtacgtgc caaaacagcc gagcactctg aaacgcctgt
    49441 tgcatctcgg cagttttgcc gtcagcagtt tctttccact gatggcgcaa cgtcgctgga
    49501 agccggatcg cattatcggc gtagtgccaa cgctgttttg cacgccggga atgcgcctgc
    49561 tggcgaaact ctctggtgcg cgtaccgtgc tgcatattca ggattacgaa gtggacgcca
    49621 tgctggggct gggccttgcc ggaaaaggca aaggcggcaa agtggcacag ctggcgacgg
    49681 cgttcgaacg tagcggactg cataacgtcg ataacgtctc cacgatttcg cgttcgatga
    49741 tgaataaagc catcgaaaaa ggcgtggcgg cggaaaacgt cattttcttc ccaaactggt
    49801 cggaaatcgc ccgttttcag catgtcgcag acgccgatgt tgatgccctt cgtaaccagc
    49861 ttggcctgcc ggataacaaa aaaatcattc tttactccgg caatattggt gaaaagcagg
    49921 ggctggaaaa cgttattgaa gctgccgatc gcctgcgcga tgaaccgctt atttttgcca
    49981 ttgtcgggca gggcggcggc aaagcgcggc tggaaaaaat ggcgcagcag cgtggactgc
    50041 gcaacatgca attttttccg ctgcaatcgt atgacgcttt acccgcactg ctgaagatgg
    50101 gggattgcca tctggtggtg caaaaacgcg gcgcggcaga tgccgtattg ccgtcgaaac
    50161 tgaccaatat tctggcggta ggcggtaacg cggtgattac cgcagaagcc cacaccgaac
    50221 tggggcagct ttgcgaaacc tttccgggca ttgcggtttg cgtggaaccg gaatcggtcg
    50281 aggcgctggt ggcggggatt cgtcaggcgc tcctgctgcc caaacacaac acggtggcac
    50341 gtgaatatgc cgaacgcacg ctcgataaag agaacgtgtt acgtcaattt ataaatgata
    50401 ttcggggata attatggcgc agtcgaaact ctatccagtt gtgatggcag gtggctccgg
    50461 tagccgctta tggccgcttt cccgcgtact ttaccccaag cagtttttat gcctgaaagg
    50521 cgatctcacc atgctgcaaa ccaccatctg ccgcctgaac ggcgtggagt gcgaaagccc
    50581 ggtggtgatt tgcaatgagc agcaccgctt tattgtcgcg gaacagctgc gtcaactaaa
    50641 taaactcacc gagaacatta ttctcgaacc ggcggggcgt aacaccgcac ctgccattgc
    50701 gctggcggcg ctggcggcaa aacgtcatag cccggagaac gacccattaa tgctggtgct
    50761 ggcggcggat catgtgattg ccgatgaaga cgcgttccgt gccgccgtgc gtaatgccat
    50821 gccgtatgcc gaagcgggca agctggtgac cttcggcatt gtgccggatc tacctgaaac
    50881 cggatatggc tatattcgtc gcggtgaagt gtcggcgggt gagcaggata cggtggcctt
    50941 tgaagtggcg cagtttgtcg aaaaaccgaa tctggaaacc gcgcaggcct atgtggcaag
    51001 tggcgaatat tactggaaca gcggtatgtt cctgttccgt gccggacgtt atctcgaaga
    51061 actgaaaaag tatcgtccgg atattctcga tgcctgtgaa aaagcgatga gcgccgtcga
    51121 tccggatctc gattttattc gtgtggatga agaggcgttt ctcgcctgtc cggaagagtc
    51181 ggtagattac gcggtcatgg aacgcacggc agatgccgtt gtggtgccga tggatgcggg
    51241 ctggagtgat gtcggttcct ggtcctcttt atgggagatc agtgcccaca ccgccgaggg
    51301 caacgtttgc catggcgatg tgattaatca caaaactgaa aacagctatg tgtatgccga
    51361 atctggcctg gtcaccaccg tcggggtgaa agatttggtg gtagtgcaga ccaaagatgc
    51421 agtgctgatt gctgaccgta acgcggtgca ggatgtgaaa aaagtggtcg agcagatcaa
    51481 agctgatggt cgccatgagc atcgggtgca tcgcgaagtg tatcgtccgt ggggcaaata
    51541 tgactctatc gacgcgggcg accgctacca ggtgaaacgc atcaccgtga aaccgggcga
    51601 agggttgtcg gtacagatgc atcatcaccg cgcggaacac tgggtggttg tcgcgggaac
    51661 ggcaaaagtc actatcgacg gtgatatcaa actgcttggt gaaaacgagt ccatttatat
    51721 tccgctgggg gcgacgcatt gcctggaaaa cccggggaaa attccgctcg atttaattga
    51781 agtgcgctcc ggctcttatc tcgaagagga tgatgtggtg cgcttcgcgg atcgctacgg
    51841 acgggtgtaa acgtcgcatc aggcaatgaa tgcgaaaccg cgatgtaaat aacgacaaaa
    51901 acaaaattgg ccgtttcggt cagggccaac tattgcctga aaaagggtaa cgatatgaaa
    51961 aaattaacct gctttaaagc ctatgatatt cgcgggaaat taggcgaaga actgaatgaa
    52021 gatatcgcct ggcgcattgg tcgcgcctat ggcgaatttc tcaaaccgaa aaccattgtg
    52081 ttaggcggtg atgtccgcct caccagcgaa accttaaaac tggcgctggc gaaaggttta
    52141 caggatgcgg gcgtcgacgt gctggatatc ggcatgtccg gcaccgaaga aatctatttc
    52201 gccacgttcc atctcggcgt ggatggcggc attgaagtta ccgccagcca taacccgatg
    52261 gattacaacg gcatgaagct ggtgcgcgaa ggggctcgcc cgatcagcgg cgataccgga
    52321 ctgcgcgacg tccagcgtct ggcagaagcc aacgactttc ctcccgtcga tgaaaccaaa
    52381 cgcggtcgct atcagcaaat caatctgcgt gacgcttacg ttgatcacct gttcggttat
    52441 atcaacgtca aaaacctcac gccgctcaag ctggtgatta actccgggaa cggcgcggcg
    52501 ggtccggtgg tggacgccat tgaagcccgc tttaaagccc tcggcgcacc ggtggagtta
    52561 atcaaagtgc ataacacgcc ggacggcaat ttccccaacg gtattcctaa cccgctactg
    52621 ccggaatgtc gcgacgacac ccgcaatgcg gtcattaaac acggcgcgga tatgggcatt
    52681 gcttttgatg gcgattttga ccgctgtttc ctgtttgacg aaaaagggca gtttatcgag
    52741 ggttactaca ttgtcggttt gctggcagaa gcgttcctcg aaaaaaatcc cggcgcgaag
    52801 atcatccacg atccacgtct ctcctggaac accgttgatg tggtgactgc cgcaggcggc
    52861 accccggtaa tgtcgaaaac cggacacgcc tttattaaag aacgtatgcg caaggaagac
    52921 gccatctacg gtggcgaaat gagcgcccac cattacttcc gtgatttcgc ttactgcgac
    52981 agcggcatga tcccgtggct gctggtcgcc gaactggtgt gtctgaaagg aaaaacgctg
    53041 ggcgaactgg tgcgcgaccg gatggcggca ttcccggcaa gcggtgagat caacagcaaa
    53101 ctggcgcaac ccgttgaggc gattaaccgc gtggaacagc attttagccg tgaggcactg
    53161 gcggtggatc gtaccgatgg catcagcatg acctttgccg actggcgctt taatctgcgc
    53221 tcctccaaca ccgaaccggt ggtgcggttg aatgtggaat cacgcggtga tgtgccgctg
    53281 atggaagcgc gaacgcgaac tctgctgacg ttgctgaacg agtaatgtcg gatcttccct
    53341 tacccccact gcgggtaagg ggctaaaaac aggaacaacg atgacaaatc taaaaaagcg
    53401 cgagcgagcg aaaaccaatg catcgttaat ctctatggtg caacgctttt cagatatcac
    53461 catcatgttt gccgggctat ggctggtttg cgaagtgagc ggactgtcat tcctctacat
    53521 gcacctgttg gtggcgctga ttacgctggt ggtgttccag atgctgggcg gcatcaccga
    53581 tttttatcgc tcatggcgcg gtgttcgggc agcgacagaa tttgccctgt tgctacaaaa
    53641 ctggacgtta agcgtgattt tcagcgccgg actggtggcg ttcaacaatg atttcgacac
    53701 gcaattgaaa atctggctgg cgtggtatgg gctgaccagc atcggactgg tggtttgccg
    53761 ttcatgtatt cgtattgggg cgggctggct gcgtaatcat ggctataaca agcgcatggt
    53821 cgcggtggcg ggggatttag ccgccggaca aatgctgatg gagagcttcc gtaatcagcc
    53881 gtggttaggg tttgaagtgg tgggcgttta ccacgacccg aaaccgggtg gcgtttctaa
    53941 cgactgggcg ggtaatctgc aacagctggt cgaggatgcg aaagcgggca agattcataa
    54001 cgtctatatc gcgatgcaga tgtgcgacgg cgcgcgagtg aaaaaactgg tccatcaact
    54061 ggcggacacc acctgttcgg tgctgctgat ccccgatgtc tttaccttca acattctcca
    54121 ttcccgtatc gaagagatga acggcgtacc ggtggtgccg ctgtatgaca cgccgctttc
    54181 cggggttaac cgcctgataa aacgtgcgga agatattgtg ctggcgacgc ttatcctgct
    54241 gctgatctcc ccggtgctgt gctgcattgc gctggcggtg aaactgagct caccggggcc
    54301 ggttattttc cgccagactc gctacggcat ggatggcaag ccgatcaaag tgtggaagtt
    54361 ccgttccatg aaagtgatgg agaacgacaa agtggtgacc caggcgacgc agaacgatcc
    54421 gcgcgtcacc aaagtgggga actttctgcg ccgcacctcg ctggacgaat tgccgcagtt
    54481 tatcaatgtg ctgactggcg ggatgtcgat tgtcggtccg cgtccgcacg cggtggcgca
    54541 taacgaacag tatcgccagc tcattgaagg ctacatgctg cgccataaag tgaaaccggg
    54601 cattaccggc tgggcgcaga ttaacggctg gcgcggcgaa accgacacgc tggagaaaat
    54661 ggaaaaacgc gtcgagttcg accttgagta catccgcgaa tggagcgtct ggttcgatat
    54721 caaaatcgtt ttcctgacgg tattcaaggg cttcgttaac aaagcggcat attgatatga
    54781 gcttacgtga aaaaaccatc agcggcgcga agtggtcggc gattgccacg gtgatcatca
    54841 tcggcctcgg tctggtgcaa atgactgtgc tggcgcggat tatagataac caccagttcg
    54901 gtttgcttac cgtgtcgctg gtgatcatcg cgctggcaga tacgctttct gacttcggta
    54961 tcgctaactc cattattcag cgaaaagaaa tcagccacct tgaactcacc acgctgtact
    55021 ggctgaacgt cgggctgggg atcgtggtgt gcgtggcggt gtttttgttg agtgatctca
    55081 tcggcgactt gctgaataac ccggacctgg caccgttgat taaaacattg tcgctggcgt
    55141 ttgtggtgat cccccacggg caacagttcc gcgcgttgat gcaaaaggag ctggagttca
    55201 acaaaatcgg catgatcgaa accagcgcgg tgctggcggg ctttactttt acggtggtta
    55261 gcgcccattt ctggccgctg gcgatgaccg cgattctcgg ttatctggtc aatagtgcgg
    55321 tgagaacgct gctgtttggc tactttggcc gcaaaattta tcgccccggt ctgcatttct
    55381 cgctggcgtc ggtggcaccg aacttacgct ttggtgcctg gctgacggcg gacagcatca
    55441 tcaactatct caacaccaac ctttcaacgc tggtgctggc gcgtattctc ggcgcgggcg
    55501 tggctggggg atacaacctg gcgtacaacg tggccgttgt gccaccgatg aagctgaacc
    55561 cgatcatcac ccgcgtgttg tttccggcgt tcgccaaaat tcaggacgat acagaaaagc
    55621 tgcgcgtcaa cttctacaag ctgctgtcgg tggtggggat tatcaacttt ccggcgctgc
    55681 tggggctaat ggtggtgtcg aataactttg taccgctggt atttggcgaa aagtggagca
    55741 gcattattcc ggtgctgcaa ttgctgtgta ttgtggggct actgcgctcc gtgggtaacc
    55801 cgattggttc gctgctgatg gcgaaagcgc gggtcgatat cagctttaaa ttcaacgtat
    55861 tcaaaacctt tctgtttatt ccggcaatca tcattggtgg gcagatggcg ggcgcaatcg
    55921 gcgtcacgct tggcttcctg ctggtgcaga ttatcaacac cattctgagc tatttcgtga
    55981 tgattaaacc ggtgctcggt tccagttatc gccagtacat cctgagtttg tggctgccgt
    56041 tttatctctc gctgccgacg ctggtggtca gttatgcgct gggcattgtg ctgaaagggc
    56101 aactggcgct ggggatgctg ctggcggtgc aaatagccac gggcgtgctg gcgtttgtgg
    56161 tgatgattgt gctgtcgcgc catccgctgg tggtggaagt gaagcgtcag ttttgtcgca
    56221 gcgaaaaaat gaaaatgctt ttacgggcgg ggtgaatggt tgttttcggt tccggcaacg
    56281 gttgccggat gcggcgtaaa acgccttatc cgtcctgggg ggctgggctt ggatcttgta
    56341 ggtctgataa gacgcgttag cgtagcatca ggcactgaat gccggatgcg gcgtgaacgc
    56401 cttatccggc ctacggttct gtgctcggat cttgtaggcc tgataagacg cgtcagcgtc
    56461 gcatcaggca ctgaatgccg gatgcggcgt aaaacgcctt atccgtccta cggctctgtg
    56521 ctcgggtctt gtaggcctga taagacgcgt cagcgtcgca tcaggcactg aatgccggat
    56581 gcggcgtgaa cgccttatcc gtcctacggt tctgtgctcg gatcttgtag gcctgataag
    56641 acgcgtcagc gtcgcatcag gcaaaaaaca gcaatgaaaa caacaaacac agcctcacct
    56701 ggcatcaaat ttatgaggaa aaaatgaaat tacttattct gggcaaccac acttgcggca
    56761 atcgcggcga cagcgccatc ctgcgcggct tacttgatgc catcaatatc ctcaatccac
    56821 atgccgaagt ggacgtgatg agtcgctatc cggtcagttc ttcctggctg ctcaaccgcc
    56881 cggtaatggg cgatccgctg ttcctgcaaa tgaaacaaca caacagtgca gcgggcgttg
    56941 tcgggcgcgt taaaaaagtc ctccgtcgcc gttaccaaca tcaggtactg ctctcacgcg
    57001 tcaccgacac tggcaagttg cgtaatatcg ccatcgccca gggattcact gacttcgtgc
    57061 gcctgctgtc aggttacgac gccattattc aggtcggcgg atcgtttttt gtcgatctct
    57121 atggcgtgcc gcagtttgaa catgcgcttt gcacgtttat ggcgaaaaag ccgctgttta
    57181 tgattggtca cagcgtcggc ccgttccagg ataagcaatt taaccaactg gcgaactacg
    57241 tttttggtca ctgcgacgcg ctgatcctgc gcgaatcggt cagccttgat ttgatgaaac
    57301 gcagcaatat cactaccgca aaagttgaac atggcgtcga taccgcgtgg ctggtcgatc
    57361 accacacaga agacttcacc gccagctatg ctgttcaaca ctggctggac gttgccgcac
    57421 aacagaaagc ggtggccatt accctgcgtg aactggcacc gttcgacaaa cgcctcggca
    57481 ccactcaaca agcgtatgaa aaagcctttg ccggggtggt caatcgcatt ctcgacgaag
    57541 gctatcaggt gattgcgctc tccacctgta cgggcatcga cagctataac aaagacgacc
    57601 gcatggtggc gctcaatctg cgccagcaca tcagcgatcc tgcccgttac cacgtggtga
    57661 tggatgaact caacgatctg gaaatgggca aaattctggg ggcctgtgaa ctcaccgtcg
    57721 gtacgcgcct gcactccgcc attatctcaa tgaactttgc caccccggcg attgccatca
    57781 actatgaaca taaatccgcc gggatcatgc agcagctggg actaccggag atggcgattg
    57841 atatccgtca tttattagac ggcagcctgc aagcgatggt tgcggatacc ttaggccaac
    57901 ttccggcgct gaacgcacga cttaacgaag ccgtcagtcg cgaacgtcag acaggaatgc
    57961 agatggtgca gtctgtgctt gagcgcatcg gggaggtgaa atgaaggtcg gcttcttttt
    58021 attgaaattt ccgctgtcgt cggaaacctt cgtcctcaac caaatcactg cgtttattga
    58081 tatgggcttt gaggtggaga ttgtcgcgtt gcaaaaaggc gacacacaaa acacccacgc
    58141 ggcatggacg aaatacaacc ttgccgccag aacccgctgg ttacaggacg aacctacggg
    58201 caaagtggcg aagctgcgcc accgagccag ccagacctta cgcggcattc atcgtaaaaa
    58261 tacctggcag gcgctcaacc tcaaacgcta tggcgcagag tcgcggaacc tgattttgtc
    58321 tgccatttgt ggtcaggtcg caacatcgtt acatgccgat gtctttatcg cacattttgg
    58381 ccctgcgggg gtaaccgcag caaaactccg cgaactgggt gtcattcgcg gcaaaattgc
    58441 cactatcttc cacggcattg atatctccag tcgggaggtg ctcaaccatt acactcccga
    58501 atatcagcaa ctgtttcgcc gtggcgacct gatgctacca ataagcgatc tgtgggccgg
    58561 aaggctgcaa aaaatgggct gcccgaggga aaaaatcgcc gtatcgcgca tgggcgtgga
    58621 catgacgcgc tttagcccgc gtccggtgaa agcgcctgca acgccgctgg aaatcatttc
    58681 cgtcgcacgc ttaaccgaga aaaaaggcct gcatgtggcg attgaagcct gccgtcagtt
    58741 gaaagagcag ggcgtggcat ttcgctatcg catcctcggc attggcccgt gggaacgacg
    58801 cctgcgcacc ctcatcgaac aatatcaact ggaagatgtg gtggagatgc cgggctttaa
    58861 accgagccat gaagtgaaag agatgctcga tgacgcggat gtcttcctgt tgccatcggt
    58921 tacgggtgcg gatggcgata tggaaggtat tccggtggcg ctaatggaag cgatggcggt
    58981 cggtattccg gtggtttcta ctctgcatag cggaattcct gaactggtgg aggctgacaa
    59041 atccggctgg ctggtgcctg agaacgatgc tcgcgcactg gcgcaacgac tggcggcgtt
    59101 tagccaactg gacagcgacg aactggctcc tgtcgtcaaa cgtgctcgcg aaaaagtcga
    59161 acacgatttt aaccagcagg tgatcaatcg agaactcgcc agcttgctgc aggctttata
    59221 gaggagaacg catgccattt aaaaaactct cccgacgcac cttcctgacg gcaagttctg
    59281 tgcttgcctt cctccatacg cctttcgccc gcgcacttcc cgctcaacaa agcgttaaca
    59341 ttaacgacta caaccctcac gactggatcg cctcatttaa acaagccttc agcgaagggc
    59401 aaacggtcgt cgtgcccgcc ggattggttt gtgacaatat caacaccggc atcttcattc
    59461 ctcctggcaa aacgttacac atccttggaa gcctgcgcgg caacggcaaa gggcgatttg
    59521 tcttacagga cggcagccag gtgacagggg aggggggcgg cagtatgcat aacatcaccc
    59581 tggatgtgcg cggctctgac tgcaccatca aagggctggc gatgagcggc tttggtccgg
    59641 taacgcagat ttatatcggc ggcaaaaaca aacgggtcat gcacaacctg accatcgata
    59701 acctgaccgt tagccacgct aattacgcca tcttacgcca gggatttcat aaccagataa
    59761 tcggtgccaa catcaccaac tgtaagttca gcgacttaca gggcgacgct attgaatgga
    59821 acgtggcgat taacgacagt gatattttga tatccgacca tgtcatcgag cgcatcaact
    59881 gtactaatgg caaaatcaac tggggcattg gcataggcct tgcgggaagc acttatgata
    59941 ataattaccc agaagatcag gcagtgaaaa actttgtcgt ggcgaatatc acgggatcgg
    60001 attgtcggca actgatccat gttgaaaatg gtaaacattt tgttatccgt aatatcaaag
    60061 ctcgtaatat cacgccggat ttcagtaaga aagcaggtat tgataacgcc acagttgcta
    60121 tttatggttg tgacaacttt gtgattgata atattgaaat gattaatagt gccgggatgt
    60181 taatcggcta tggggtaatt aaaggcaaat atctctcgat accgcagaat ttccgagtga
    60241 atgatattca attggataat actcatcttg cttataaatt gcgcggcatc caaatctccg
    60301 ccgggaatgc tgtctccttt gtggcgctga ctaacattga gatgaagcgt gcgtcgctgg
    60361 agttacacaa caaaccgcaa catcttttta tgcgtaatat caatgtgatg caggaatcct
    60421 cagttggacc agcattgagc atgaactttg acatgcgcaa agacgttcga ggcgtgttta
    60481 tggcgaaaaa agaaacactg ctgtctcttg caaatgttca tgcggtgaat gaaaaagggc
    60541 aaagctccgt cgatatcgac aggattaatc accatattgt taatgtggaa aagattaact
    60601 ttagattgcc ggaacggaga gagtagattt gcgaccattc ctggaaaaat ggagtcatac
    60661 ttaggaacaa tgctactgca atccacaacg aagcggcgta acatcacaag taattcagta
    60721 atcaattcag ggtaattgat gctggcgaaa aaaatcgaac aagctataat tcagcaacca
    60781 ttttacaggt ggatgaaata atgacgaatt taaaagcagt tattcctgta gcgggtctag
    60841 ggatgcatat gttgcctgcc actaaggcga ttcccaaaga gatgctaccg atcgtcgaca
    60901 agccaatgat tcagtacatt gttgacgaga ttgtggctgc agggatcaaa gaaatcctcc
    60961 tggtaactca tgcgtccaag aacgcggtcg aaaaccactt cgatacatct tatgaattag
    61021 aatctctcct tgaactgcgc gtgaagcgtc aactgctggc ggaagtacag tccatctgtc
    61081 cgccgggcgt gaccattatg aacgtgcgtc agggcgaacc tttaggttta ggccactcca
    61141 ttttgtgtgc gcgacctgcc attggtgaca acccatttgt cgtggtactg ccagacgttg
    61201 tgatcgacaa tgccagcgcc gacccgctac gttacaacct tgctgccatg attgcacgtt
    61261 tcaacgaaac gggccgcagc caggtgctgg caaaacgtat gccgggtgac ctctctgaat
    61321 actccgtcat tcagactaaa gagccgctgg atcgtgaagg taaagtcagc cgcattgttg
    61381 aatttatcga aaaaccggat cagccgcaga cgctggactc agacatcatg gccgtaggtc
    61441 gctatgtgct ttctgccgat atttggccgg aactggaacg tactcagcct ggtgcatggg
    61501 gacgtattca gctgactgat gccattgctg agttggcaaa aaaacaagca gttgacgcaa
    61561 tgctgatgac tggggacagt tacgactgcg gaaagaaaat gggttatatg caagcgtttg
    61621 tgaagtatgg gctgcgtaac ctgaaggaag gggcgaagtt ccgtaaaggt attgagaagc
    61681 tgttaagcga gtaacaaatt cctgactgga agtgtcggtc agtaagtaat taaaaacggc
    61741 agtgaagatt catagcataa gttttgctca ttgaatctca ctgccgttgt cttttttata
    61801 agtacaataa aaacagcatg ttagcttgca atcatagttc aaatttttcc aggattttcc
    61861 ttgtttctac agctgtttgg taagacaatt agcgtttgaa tttttcggat ttggcacgag
    61921 tgggttacgc tcgtcacatc gtggaaatgt acgcagtgct ctggtagcgg ttaagccagg
    61981 ggcggtagcg tgcattaatg catctattaa tcaaatctgg agcagtctat ttcacagcat
    62041 gctctctggc tatatggaat aaaaaagtga agatacttgt tactggtggc gcaggattta
    62101 ttggttctgc tgttgttcgt cacataataa ataatacgca agatagtgtt gttaatgtcg
    62161 ataaattaac atacgccgga aacctggaat cacttgcaga tgtttctgat tctgaacgct
    62221 atttctttga acatgcggat atttgtgatg cagctgcaat ggcacggatt tttgctcagc
    62281 atcagccgga tgcagtgatg cacctggcag ctgaaagcca tgttgaccgt tcaattacag
    62341 gccctgcggc atttattgaa accaatattg tgggtactta tgtcctttta gaagcggctc
    62401 ggaattattg gtctggtctg gatgatgaaa agaaaaaaaa cttccgtttt catcatattt
    62461 ctactgatga ggtgtatggt gacttacccc atccggatga agtaaatagc aatgaaacgt
    62521 tgccgctatt tacggaaacg acagcatacg cgccaagtag tccatattct gcttctaaag
    62581 cttccagcga tcatttggtt cgcgcatgga aacgtactta tggtttaccg accattgtga
    62641 ctaattgctc gaacaactat ggtccttatc atttcccgga aaagcttatt ccactggtta
    62701 ttcttaattc actggaaggt aaggcattac ctatttatgg caaaggagat cagatccgcg
    62761 actggttgta tgtagaggat catgctcgag cgttatatac cgtcgtaacc gaaggtaaag
    62821 cgggcgaaac ttataacatt ggtggacaca acgaaaagaa aaacatcgac gtagtgttca
    62881 ctatttgtga tttgttggat gagatagtcc cgaaagagaa atcttaccgc gagcaaatta
    62941 cttatgttac cgatcgtccg ggacacgatc gccgttatgc gattgatgct gagaagattg
    63001 gtcgcgaatt gggatggaaa ccacaggaaa cgtttgagag tgggattcgt aaaacggtgg
    63061 aatggtacct gtccaataca aaatgggttg ataatgtgaa aagtggtgcc tatcaatcgt
    63121 ggattgaaca gaactatgag ggccgccagt aatgaatatc ctcctttttg gcaaaacagg
    63181 gcaggtaggt tgggaactac agcgtgctct ggcacctctg ggtaatttga ttgctcttga
    63241 tgttcactcc actgattact gtggtgattt tagtaatcct gaaggtgtag ctgaaaccgt
    63301 aagaagcatt cggcctgata ttattgtcaa cgcagccgct cacaccgcag tagacaaagc
    63361 agaatcagaa ccgaagtttg cacaattact gaacgcgacg agtgtcgaag cgatcgcgaa
    63421 agcagccaat gaagtcggcg cctgggttat tcactactct actgactacg tatttccggg
    63481 gaccggtgaa ataccatggc aggaggagga tgcaaccgca ccgctaaatg tttacggtga
    63541 aaccaagtta gcgggagaaa aagcattaca agagcattgt gcgaagcacc ttattttccg
    63601 gaccagctgg gtctatgcag gtaaaggaaa taacttcgcc aaaacaatgt tgcgtctggc
    63661 aaaagagcgt gaagaattag ccgttattaa tgatcagttt ggtgcgccaa ctggcgcaga
    63721 gttactggct gattgtacgg cacatgctat tcgtgtggca ctgaataaac cggaagtcgc
    63781 aggcttgtac catctggtag ctagtggtac cacaacgtgg cacgattatg ctgcgctggt
    63841 ttttgaagag gcgcgcaaag caggcattcc ccttgcactc aacaagctca acgcagtacc
    63901 aacaacagcc tatcctacac cagctcgtcg tccacataac tctcgcctta atacagaaaa
    63961 atttcagcag aactttgcgc ttgtcttgcc tgactggcag gttggcgtga aacgaatgct
    64021 taacgaatta tttacgacta cagcaattta atagtttttg catcttgttc gtaatggtgg
    64081 agcaagatgt attaaaagga atgatgaaat gaaaacgcgt aaaggtatta ttttggcggg
    64141 tggttctggt actcgtcttt atcctgtgac gatggccgtc agtaaacagc tgttaccgat
    64201 ttatgataaa ccgatgatct attacccgct ctctacactg atgttagcgg gtattcgcga
    64261 tattctgatt atcagtacac cacaggatac tcctcgtttt caacaactgc tgggtgacgg
    64321 gagccagtgg ggcctgaatc ttcagtacaa agtgcaaccg agtccggatg gtcttgcgca
    64381 ggcgtttatt atcggtgaag agtttattgg tggtgatgat tgtgctttgg tacttggtga
    64441 taatatcttc tacggccacg acctgccgaa gttaatggac gtagctgtta acaaagaaag
    64501 tggtgcaacg gtatttgcct atcacgttaa tgatcctgaa cgttatggtg tcgtggagtt
    64561 tgataataac ggtactgcaa ttagcctgga agaaaaaccg ctggaaccaa aaagtaacta
    64621 tgcggttact gggctttatt tctatgacaa tgacgttgtg gaaatggcga aaaaccttaa
    64681 gccttctgcc cgaggtgaac tggaaattac cgatattaac cgtatttata tggaacaagg
    64741 acgtttgtct gtcgctatga tggggcgtgg ctatgcatgg ctggatacag ggacgcatca
    64801 aagtcttatt gaagcaagca acttcattgc caccattgaa gagcgccagg gactaaaggt
    64861 ttcctgtccg gaagaaattg cttatcgtaa agggtttatt gatgctgagc aggtaaaagt
    64921 attagccgaa ccgttgaaga aaaatgctta tggtcagtat ctgctcaaaa tgattaaagg
    64981 ttattaataa gatgaacgta attaaaactg aaattcctga tgtgctgatt tttgaaccaa
    65041 aagtttttgg ggatgaacgt ggcttctttt ttgagagttt taatcagagg atttttgaag
    65101 aagcagtagg tcgtaaggtt gagtttgttc aggataacca ttctaagtcc agtaaaggtg
    65161 ttttacgtgg tcttcattat cagttagaac cttatgctca aggaaaactg gtgcgctgtg
    65221 ttgttggcga ggtttttgat gttgcggttg atattcgtaa atcgtcacct acatttggga
    65281 aatgggttgg ggtgaatttg tctgctgaga ataagcgtca gttgtggatt cctgagggat
    65341 ttgcacatgg ttttttggtg ctgagtgatt tagcagaagt tttatataaa acgaatcaat
    65401 att
//
LOCUS       DAFGPF010000012        63859 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFGPF010000012 DAFGPF010000000
VERSION     DAFGPF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 63859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63859
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.012"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(238..1260)
                     /locus_tag="LSX49_000935"
     CDS             complement(238..1260)
                     /locus_tag="LSX49_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrD"
                     /protein_id="HBL7167377.1"
                     /translation="MDKRVIFAVAGSGKTTLLIRRLREDRRTLILTFTVNNEAHLRAQ
                     IIRRFGYIPYGIRVMTWFEFLHGFCFRPFLQEQLSSRGLSFNQPPSRIPRTNIRHYQD
                     PAGRLYHRRLAHLLTARGLLPDIRTRLARYYDELFVDEVQDFAGHDFNFLLELCRAEI
                     SVLCCGDFYQHTFDTSRDGNVNATLHEDITRYEARFRAAGIMVDCETLSRTWRCSATV
                     CEFITGQLNIRISAHGTHTTQIEIVTDEARSAALHADNTMIKLFYREHHRYGCHSMNW
                     GGSKGLDHFQDVCIVMGANHWMRLIQQKLAALPPSSRNRLYVACSRARGNIYFIPESH
                     LRRFRN"
     gene            complement(1245..2810)
                     /locus_tag="LSX49_000936"
     CDS             complement(1245..2810)
                     /locus_tag="LSX49_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7167378.1"
                     /translation="MPLITRLMLQNFKKFPELDLRFSNDRNILVGDNESGKSTILLAL
                     DLVLSDSRHRVEALGVESLLSQSAVRHFQEGERRADQLPVLTADVFLSNGGEPDLNGR
                     QNLAGIDADGLRMRIAPMMEEYGQDIHHVLQQDPDNFPYEYYSVQFSTFSGGHFAGFR
                     RYLRHLFLDSARIDNEHAAQEYTRTVYSVNVPVADRYRLENSYRQQKMHFCARHLSAI
                     NDTLKTYQFGVRSGAKSGLEANLDITEDGISIRHRGKGRQCFIKTEFALQRHQQQGGE
                     IHALLLEEPENHLSHVSMKRLVNQLATERQTQVFIATHSSHISSRLDLRKAILLGATR
                     PVLMNELSAETAAFFMKAPDNNVLEFALARRVLLVEGDAEFILIEAFYHRLYGRAPED
                     DGVHIIAIGGTSFRRYLELARLLENRVAALRDNDGNYQQNCDERYADVLCSRSRVFAD
                     HDNSRSTFEICLYQDNADLCDALFRGTRRTLTVQDYMLANKAEAAFQLLQLHAEKLTV
                     PDYIQEALAWIRE"
     gene            complement(2885..3301)
                     /locus_tag="LSX49_000937"
     CDS             complement(2885..3301)
                     /locus_tag="LSX49_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HBL7167379.1"
                     /translation="MNKIYMLDTNICSFIMREQPEALLKHLEQSVLRGHRIVVSAITY
                     SEMRFGATGPKASPRHVQLVDAFCERLDAVLPWDRAAVDATTEIKVALRLAGTPIGPN
                     DTAIAGHAIAACAILVTNNVREFERVPGLVLEDWVR"
     gene            complement(3298..3528)
                     /locus_tag="LSX49_000938"
     CDS             complement(3298..3528)
                     /locus_tag="LSX49_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBL7167380.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVR
                     PTWGSFLELEKADPDFMTEREDVVSDEGRVNL"
     gene            4088..4306
                     /gene="ccdA"
                     /locus_tag="LSX49_000939"
     CDS             4088..4306
                     /gene="ccdA"
                     /locus_tag="LSX49_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HBL7167381.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTLQNEARRLRAERW
                     QAENQEGMAEVARFIEMNGSFADENRDW"
     gene            4308..4613
                     /gene="ccdB"
                     /locus_tag="LSX49_000940"
     CDS             4308..4613
                     /gene="ccdB"
                     /locus_tag="LSX49_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HBL7167382.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHVGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            4614..5420
                     /locus_tag="LSX49_000941"
     CDS             4614..5420
                     /locus_tag="LSX49_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBL7167383.1"
                     /translation="MSGSVIHSQSAAMVPAVYSAGQSAQLPVAIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPF
                     VQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVAMLKQLS"
     gene            6142..6897
                     /gene="repE"
                     /locus_tag="LSX49_000942"
     CDS             6142..6897
                     /gene="repE"
                     /locus_tag="LSX49_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="HBL7167384.1"
                     /translation="MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVD
                     QIRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEED
                     AGDEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNP
                     YAMRLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINS
                     RTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG"
     gene            7485..8651
                     /gene="sopA"
                     /locus_tag="LSX49_000943"
     CDS             7485..8651
                     /gene="sopA"
                     /locus_tag="LSX49_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="HBL7167385.1"
                     /translation="MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGE
                     AADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAE
                     DVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDL
                     HIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPT
                     DPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQ
                     FFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRE
                     TDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
     gene            8651..9622
                     /locus_tag="LSX49_000944"
     CDS             8651..9622
                     /locus_tag="LSX49_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition
                     protein"
                     /protein_id="HBL7167386.1"
                     /translation="MKRAPVIPKHTLNTQPVEDTSLSTPAAPMVDSLIARVGVMARGN
                     AITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDALDDLIPSFLLTGQQ
                     TPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSA
                     YERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSA
                     RSGDALQKAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLS
                     SRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEKPAP"
     gene            10360..11262
                     /locus_tag="LSX49_000945"
     CDS             10360..11262
                     /locus_tag="LSX49_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HBL7167387.1"
                     /translation="MYFSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLL
                     QTTEDVRFEPCPGLTAAGRGVVSPENIAFTRWLTHLQDGVLLDEQNCLMLHELWLQSG
                     TGQRRWEGLPDDVRDTITALFTAKRGDWCGFWSNEAVSVWWNRLCDNVLPEKTMPFDL
                     LTVLPTRLDVEVNGFNGGVLNGVLSAYHWYTEQYGVKWPVGYEVNISSQGDNFIQVDF
                     DTPWCQPESDVIAELSRRFSCTMEHWYAEQGCNFCGWQRYERGELVDVLWGELEWSSP
                     TDDDELPEVTGPAWIVDNVAHYGG"
     gene            11266..11570
                     /locus_tag="LSX49_000946"
                     /pseudo
     CDS             11266..11570
                     /locus_tag="LSX49_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052644.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11647..12330
                     /locus_tag="LSX49_000947"
     CDS             11647..12330
                     /locus_tag="LSX49_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HBL7167388.1"
                     /translation="MSRFVLGNCIDVMARIPDNAIDFILTDPPYLVGFRDRFGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPRLPQNPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVVALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DNWFEPEAA"
     gene            12331..12552
                     /locus_tag="LSX49_000948"
     CDS             12331..12552
                     /locus_tag="LSX49_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167389.1"
                     /translation="MNYAGHEKLRADVAEVANTMCDLRARLNDMEHRCRFDSDVLVER
                     LTRQTLYRANRLFMEAYTEILELDSCFKD"
     gene            12566..13000
                     /locus_tag="LSX49_000949"
     CDS             12566..13000
                     /locus_tag="LSX49_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HBL7167390.1"
                     /translation="MYGTCETLCRELAAKYPGNTPLMLLIWSPEEIQALADGMDISLS
                     DHEIRTVLARLEDIPEDQRTESGISSGAAMEIINNVRENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDNGLAVPECVTRRQAVVNQARALLKNNTREND"
     gene            13045..13815
                     /locus_tag="LSX49_000950"
     CDS             13045..13815
                     /locus_tag="LSX49_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167391.1"
                     /translation="MNETLNALIYRHASNLLLAQGWPEETDVDQRNPKYPGWISIYVR
                     LDVPRLATLLINRHGGVLPPLLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVFF
                     PYAGEWLTEDEIRAVLDAVRNAVRSICYQVAEDARRIRAALTTTGQTLLTRQTRRFRL
                     VVKESDYPCWLDEDDENLPVVLDAILNRGARFSSVEMYLVSECVEHILSSGLACDVLR
                     IPDEPSRRWFDRDILREMVLEARTEIRSMADALAKIRK"
     gene            14352..14654
                     /locus_tag="LSX49_000951"
     CDS             14352..14654
                     /locus_tag="LSX49_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBL7167392.1"
                     /translation="MMPEYEGGFWHFIRLPDGGGYMMPDGDRFHLVNGENWFDRTVSA
                     DAAGIILTSLVINRQLWLYHDSGDAGLTHLYRMRDAQLWSHIEFHPECNAIYAALD"
     gene            14701..15123
                     /locus_tag="LSX49_000952"
     CDS             14701..15123
                     /locus_tag="LSX49_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HBL7167393.1"
                     /translation="MYCTVKEIIRDVLDTDVPDSECVFAVVLTRGDVRHIAQDWNLSD
                     DELETVMQRLDDAFEYGADVSIVHDVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGEHMS"
     gene            15120..15311
                     /locus_tag="LSX49_000953"
     CDS             15120..15311
                     /locus_tag="LSX49_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167394.1"
                     /translation="MNISTETREILRNYKAVINARRREMGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(15583..15831)
                     /locus_tag="LSX49_000954"
     CDS             complement(15583..15831)
                     /locus_tag="LSX49_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001403191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167395.1"
                     /translation="MSRDPPQRRRARARNGVAPYIPAAFCRDAGSAGHGATEAARPER
                     SLQACGFHASDRSDSPKPRQRVRRRLAGAPAAACRSRA"
     gene            16343..16573
                     /locus_tag="LSX49_000955"
     CDS             16343..16573
                     /locus_tag="LSX49_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167396.1"
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            16625..17986
                     /locus_tag="LSX49_000956"
     CDS             16625..17986
                     /locus_tag="LSX49_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HBL7167397.1"
                     /translation="MTSAAITMTAPEAASPVQMYRATYSPDDNKLRLYAVSRLDPETY
                     KKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDHISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLDESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFREMTKAQWAALPRDCKAVRSVAEAEDHGAYRYRRTMDNNFRLVNVYITDMKITEI
                     PQK"
     gene            18034..18599
                     /locus_tag="LSX49_000957"
                     /pseudo
     CDS             18034..18599
                     /locus_tag="LSX49_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            18625..18837
                     /locus_tag="LSX49_000958"
     CDS             18625..18837
                     /locus_tag="LSX49_000958"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167398.1"
                     /translation="MPVCPRREKTRAGGAERGRAHAPPLSLRGRSDGGFCFFMPVICL
                     LLMLLFLLLLLLLLLLLLLFFFFLLL"
     gene            19247..19453
                     /locus_tag="LSX49_000959"
     CDS             19247..19453
                     /locus_tag="LSX49_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL7167399.1"
                     /translation="MYIPQNFLPRSRQKLLRSAPGQSFPAVAVMPLAAKVLKKVMVNT
                     GGNKRQVPAKRQNRGSRNSKDDGG"
     gene            20131..22032
                     /gene="ltrA"
                     /locus_tag="LSX49_000960"
     CDS             20131..22032
                     /gene="ltrA"
                     /locus_tag="LSX49_000960"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL7167400.1"
                     /translation="MLPDELEKRLDGIEDASKKGYPVRNLYKIACEPGLWLQAYVNIR
                     ANAGALTQGVSTDTIDGFSIERAEKLAKTLRSREYVAKPVRRVQIPKKDGKTRPLGIP
                     GGDDKLAQEVARIILERVYEPVFSEHSHGFRPKRSCETALRSIRPVWNGVKWIVDVDI
                     KGFFDNIPHKLLLNTLAEKIKDKNFLKLIEQWLKAGYVDNWKYHRSYSGTPQGGIISP
                     LLANIYLDKLDRFVEQNLIPAYTSGTKRRANPDMNRLAHKIHKLRKKVDGMATDSESE
                     KEAIKKEIERLLEEKRSIPSQVMNDPNFRRMYYVRYADDFVIGVIGSKKDAEHISRQV
                     RNFITTSLGLEVNEAKTRIRHISEGVNFLGYEIRQADAKKLLKQKMQGRHALRRSTTG
                     IVQLFVPDNIAAKFCHQKKYGCYENVKAVHRSSLQNLSEAEIVLTFNAEMRGLANYYS
                     LALDMKYKLSKLYFIWQISLFKTLANKRRSSVNKVAKSLRQNNGDLAITVQAKNGSRK
                     IEVFKLKHVNRNRTTIVDTEPRTAHITTRTTEIMRRLGARICEYCAKTGRCEVHHVRK
                     LKDLKKGRKAGYKPSLWQLMMIARRRKTMILCASCHDKLHSGKLPDLRQEKGRILLQP
                     PVSSGDSAK"
     gene            22182..22679
                     /gene="ssb"
                     /locus_tag="LSX49_000961"
     CDS             22182..22679
                     /gene="ssb"
                     /locus_tag="LSX49_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000741240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL7167401.1"
                     /translation="MGKDPEVRYIPNGGAVANLQVATSETWRDKQTGEMREQTEWHRV
                     VLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEILVKTTGTMQMLGRAA
                     GAQTQPEEGQQFSGQPQPEPQAEAGTKKGGAKTKGRGRKAAQPEPQPQPPEGDDYGFS
                     DDIPF"
     gene            22747..22980
                     /locus_tag="LSX49_000962"
     CDS             22747..22980
                     /locus_tag="LSX49_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HBL7167402.1"
                     /translation="MSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIEDDHGEQFRLV
                     VRNNGAMVWRTWNFEDGAGYWMNHVIRDFGILK"
     gene            23008..23205
                     /locus_tag="LSX49_000963"
                     /pseudo
     CDS             23008..23205
                     /locus_tag="LSX49_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            23260..23694
                     /gene="psiB"
                     /locus_tag="LSX49_000964"
     CDS             23260..23694
                     /gene="psiB"
                     /locus_tag="LSX49_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HBL7167403.1"
                     /translation="MKTELTLNVLQTMNTQEYEDIRAAGSDERRELTHAVMREQDAPD
                     NWTMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQVWVLVLVNAGGEPFAVV
                     QVQRRFAPEAVSHSLALAASLDAQGYSVSDIIHILMAEGSQA"
     gene            23691..24410
                     /locus_tag="LSX49_000965"
     CDS             23691..24410
                     /locus_tag="LSX49_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001763821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HBL7167404.1"
                     /translation="MSARSQALVPLSTEQQAAWRAVAETEKRRHQGNTLAEYPYAGAF
                     FRCLNGSRRISLSDLRFFMPSLTAEELHGNRLQWLYAIDVLIETQGEVCLLPLPGDAA
                     ERLFPSVRFRVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVAQAEIELAFHSPE
                     TVGSWYARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEAGMAARV
                     VGHAVREMERWMVPNKLREAA"
     gene            complement(24422..24610)
                     /locus_tag="LSX49_000966"
     CDS             complement(24422..24610)
                     /locus_tag="LSX49_000966"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein sok"
                     /protein_id="HBL7167405.1"
                     /translation="MKINLLRGYLLSATQHGNKPPSRHEAESLKRRAHHSPYTCTLTT
                     LTFPENNPLIQTVHGKSV"
     gene            24690..24848
                     /locus_tag="LSX49_000967"
     CDS             24690..24848
                     /locus_tag="LSX49_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HBL7167406.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAA
                     FMAYESGK"
     gene            25769..26056
                     /locus_tag="LSX49_000968"
     CDS             25769..26056
                     /locus_tag="LSX49_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167407.1"
                     /translation="MSTRNIHVNTASYTLLVAGKKKNTGEEWDVLEFSSLTELKKYRK
                     SHPEKMAFSYSYALSQGVDKQFRHINIAEADHFKQFLRQIKRAGLDIRAIC"
     gene            26174..26995
                     /locus_tag="LSX49_000969"
     CDS             26174..26995
                     /locus_tag="LSX49_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBL7167408.1"
                     /translation="MRLASRFGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSERY
                     TYIPTINIINKLRDEGFQPFFACQSRIRDLGRREYSKHMLRLRREGHINGQEVPEIIL
                     LNSHDGSSSYQMIPGIFRFVCTNGLVCGNNFGEIRVPHKGDIVGQVIEGAYEVLGVFD
                     KVTDNMEAMKEIHLNSDEQHLFGRAALMVRYEDENKTPVTPEQIITPRRREDKQNDLW
                     TTWQRVQENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWVIAEQFRKWKS"
     gene            complement(27292..27894)
                     /locus_tag="LSX49_000970"
     CDS             complement(27292..27894)
                     /locus_tag="LSX49_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HBL7167409.1"
                     /translation="MVLLVVRTTNLLSLFVEWVKLFTDKVTRGGKMKKWMLTICLMFI
                     NEICQATDCFDLAGRDYKIDPDLLRAISWQESRYRVNAIGINPVTGYGSGLMQVDSQH
                     FNELARYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVTWEAVGAYNAGFRKTERQNQ
                     RRLAYASDVYRIYTGIKSSKGIRLPATKKSLPEINSVQNN"
     gene            28215..28598
                     /locus_tag="LSX49_000971"
     CDS             28215..28598
                     /locus_tag="LSX49_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome protein TraM"
                     /protein_id="HBL7167410.1"
                     /translation="MAKVNLYISNDAYEKINAIIEKRRQEGAREKDVSFSATASMLLE
                     LGLRVHEAQMERKESAFNQTEFNKLLLECVVKTQSSVAKILGIESLSPHVSGNPKFEY
                     ANMVEDIREKVSSEMERFFPKNDDE"
     gene            28785..29474
                     /gene="traJ"
                     /locus_tag="LSX49_000972"
     CDS             28785..29474
                     /gene="traJ"
                     /locus_tag="LSX49_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer transcriptional regulator
                     TraJ"
                     /protein_id="HBL7167411.1"
                     /translation="MYPMDRIQQKHARQIDLLENLTAVIQDYPNPACIRDETGKFIFC
                     NTLFHESFLTQDQSAEKWLLSQRDFCELISVTEMEAYRNEHTHLNLVEDVFIQNRFWT
                     ISVQSFLNGHRNIILWQFYDAAHVRHKDSYNQKTIVSDDIRNIIRRMSDDSSVSSYVN
                     DVFYLYSTGISHNAIARILNISISTSKKHASLICDYFSVSNKDELIILLYNKKFIYYL
                     YEKAMCIINTR"
     gene            29573..29968
                     /gene="traY"
                     /locus_tag="LSX49_000973"
     CDS             29573..29968
                     /gene="traY"
                     /locus_tag="LSX49_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer relaxosome protein TraY"
                     /protein_id="HBL7167412.1"
                     /translation="MKRFGTRSATGKMVKLKLPVDVESLLIEASNRSGRSRSFEAVIR
                     LKDHLHRYPKFNRAGNIYGKSLVKYLTMRLDDETNQLLIAAKNRSGWCKTDEAADRVI
                     DHLIKFPDFYNSEIFREADKEEDITFNTL"
     gene            30001..30366
                     /gene="traA"
                     /locus_tag="LSX49_000974"
     CDS             30001..30366
                     /gene="traA"
                     /locus_tag="LSX49_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system pilin TraA"
                     /protein_id="HBL7167413.1"
                     /translation="MNAVLSVQGASAPVKKKSFFSKFTRLNMLRLARAVIPAAVLMMF
                     FPQLAMAAGSSGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFL
                     AGFAIISVFIAVGMAVVGL"
     gene            30381..30692
                     /gene="traL"
                     /locus_tag="LSX49_000975"
     CDS             30381..30692
                     /gene="traL"
                     /locus_tag="LSX49_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HBL7167414.1"
                     /translation="MSGDENKLKKYRFPETLTNQSRWFGLPLDELIPAAICIGWGITT
                     SKYLFGIGAAVLVYFGIKKLKKGRGSSWLRDLIYWYMPTALLRGIFHNVPDSCFRQWI
                     K"
     gene            30714..31280
                     /gene="traE"
                     /locus_tag="LSX49_000976"
     CDS             30714..31280
                     /gene="traE"
                     /locus_tag="LSX49_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HBL7167415.1"
                     /translation="MEHGARLSTSRVMAIAFIFMSVLIVLSLSVNVIQGVNNYRLQNE
                     QRTAVTPMAFNAPFAVSQNSADASYLQQMALSFIALRLNVSSETVDASHQALLQYIRP
                     GAQNQMKVILAEEAKRIKNDNVNSAFFQTSVRVWPQYGRVEIRGVLKTWIGDSKPFTD
                     IKHYILILKRENGVTWLDNFGETDDEKK"
     gene            31291..31995
                     /gene="traK"
                     /locus_tag="LSX49_000977"
     CDS             31291..31995
                     /gene="traK"
                     /locus_tag="LSX49_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HBL7167416.1"
                     /translation="MFGSLFFSCSVMAANGTLAPTVVPMVNGGQASIAISNTSPNLFT
                     VPGDRIIAVNSLDGALTNNEQTASGGVVVATVNKKPFTFILETERGLNLSIQAVPREG
                     AGRTIQLVSDLRGTGEEAGAWETSTPYESLLVTISQAVRGGKLPAGWYQVPVTKETLQ
                     APAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLL
                     AGARMDVYVIRDGEGN"
     gene            31995..33422
                     /locus_tag="LSX49_000978"
     CDS             31995..33422
                     /locus_tag="LSX49_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraB"
                     /protein_id="HBL7167417.1"
                     /translation="MASINTIVKRKQYLWLGIVVVGTASAIGGALYLSDVDMSGNGET
                     VAEQEPVPDMTGVVDTTFDDKVRQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGDD
                     QRRIEKLGQDNAALAEQVKALGANPVTATGEPVPQMPASPPGPEGEPQPGNTPVSFPP
                     QGSVAVPPPTAFYPGNGVTPPPQVTYQSVPVPNRIQRKVFTRNEGKQGPSLPYIPSGS
                     FAKAMLIEGADANASVTGNESTVPMQLRITGLVEMPNSKTYDATGCFVGLEAWGDVSS
                     ERAIVRTRNISCLKDGKTIDMPIKGHVSFRGKNGIKGEVVMRNGKILGWAWGAGFVDG
                     IGQGMERASQPAVGLGATAAYGAGDVLKMGIGGGASKAAQTLSDYYIKRAEQYHPVIP
                     IGAGNEVTVVFQDGFQLKTVEEMALERTQSRAEEDNPESPVPVPPSAESHLNGFNTDQ
                     MLKQLGNLNPQQFMSGSQGGGNDGK"
     gene            33412..34002
                     /locus_tag="LSX49_000979"
     CDS             33412..34002
                     /locus_tag="LSX49_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HBL7167418.1"
                     /translation="MANNMSSRQACHAARYVVARVLRGLFWCLKYTVILPLATMALMA
                     LFVLWKDNTTPGKLLVKEINFVRQTAPAGQFPVSECWFSSSDSSGRSEIQDICHYRAA
                     DAADYVRETDRSLMQLVTALWATLALMYVSLAAITGKYPVRPGKMKCIRVVTADEHLK
                     EVYTEDASLPGKIRKCPVYLPDDRTNRNNGDKNEHA"
     gene            33956..34186
                     /locus_tag="LSX49_000980"
     CDS             33956..34186
                     /locus_tag="LSX49_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbD"
                     /protein_id="HBL7167419.1"
                     /translation="MTEQTETTEIKMNMRNINVITALSVPGKTVSDDFMHAVLSNCAT
                     RIVLPAPEKFGSESLPDNFNMTAVGVMKNSEI"
     gene            34198..34449
                     /gene="trbG"
                     /locus_tag="LSX49_000981"
     CDS             34198..34449
                     /gene="trbG"
                     /locus_tag="LSX49_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbG"
                     /protein_id="HBL7167420.1"
                     /translation="MNKLVSDGSVKKINYPVLYESGITPPLCEVSAPEPDAGGKRIVA
                     YVYKSSRSTVFENPDIVKTCTVRDLKKDFVNCDEKGEGQ"
     gene            34446..34961
                     /gene="traV"
                     /locus_tag="LSX49_000982"
     CDS             34446..34961
                     /gene="traV"
                     /locus_tag="LSX49_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system lipoprotein
                     TraV"
                     /protein_id="HBL7167421.1"
                     /translation="MKQISFFIPLLGTLLLSGCAGTSTEFECNATTSDTCMTMEQANE
                     KAKKLEQSSEAKPVAASLPRLAEGNFRTMPVQTVTATTPSGSRPAVTAHPEQKLLAPR
                     PLFTAAREVKTVVPVSSVTPVTPPRPLRTGEQTAALWIAPYIDNQDVYHQPSSVFFVI
                     KPSAWGKPRIN"
     gene            35096..35317
                     /gene="traR"
                     /locus_tag="LSX49_000983"
     CDS             35096..35317
                     /gene="traR"
                     /locus_tag="LSX49_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HBL7167422.1"
                     /translation="MSDEADEAYSVTEQLTMTGINRIRQKINAHGIPVYLCEACGNPI
                     PEARRKIFPGVTLCVECQAYQERQRKHYA"
     gene            35477..38104
                     /gene="traC"
                     /locus_tag="LSX49_000984"
     CDS             35477..38104
                     /gene="traC"
                     /locus_tag="LSX49_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HBL7167423.1"
                     /translation="MNNPLEAVTQAVNSLVTALKLPDESAKANEVLGEMSFPQFSRLL
                     PYRDYNQESGLFMNDTTMGFMLEAIPINGANESIVEALDHMLRTKLPRGIPLCIHLMS
                     SQLVGDRIEYGLREFSWSGEQAERFNAITRAYYMKAAATQFPLPEGMNLPLTLRHYRV
                     FISYCSPSKKKSRADILEMENLVKIIRASLQGASITTQTVDAQAFIDIVGEMINHNPD
                     SLYPKRRQLDPYSDLNYQCVEDSFDLKVRADYLTLGLRENGRNSTARILNFHLARNPE
                     IAFLWNVADNYSNLLNPELSISCPFILTLTLVVEDQVKTHSEANLKYMDLEKKSKTSY
                     AKWFPSVEKEAKEWGELRQRLGSGQSSVVSYFLNITAFCKDNNETALEVEQDILNSFR
                     KNGFELISPRFNHMRNFLTCLPFMAGKGLFKQLKEAGVVQRAESFNVANLMPLVADNP
                     LTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGG
                     FAVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERVRDQLSVMASPNG
                     NLDEVHEGLLLQAVRASWLAKENRARIDDVVDFLKNASDSEQYAESPTIRSRLDEMIV
                     LLDQYTANGTYGQYFNSDEPSLRDDAKMVVLELGGLEDRPSLLVAVMFSLIIYIENRM
                     YRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSD
                     KASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFLPLQRDMIGKFGAAKDQWFSS
                     FLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAVWQLAWKKSGP
                     EMASLEAWLEEHEKYRSVA"
     gene            38101..38487
                     /gene="trbI"
                     /locus_tag="LSX49_000985"
     CDS             38101..38487
                     /gene="trbI"
                     /locus_tag="LSX49_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TrbI"
                     /protein_id="HBL7167424.1"
                     /translation="MSSTQKPADVMAERRSHWWWTVPGCLAMVLLNAAVSYGIVRLNA
                     PVTVAFNMKQTVDAFFDRASQKQLSEAQSKALSARFNTALEASLQAWQQKHHAVILVS
                     PAVVQGAPDITREIQQDIARRMRAEP"
     gene            38484..39116
                     /gene="traW"
                     /locus_tag="LSX49_000986"
     CDS             38484..39116
                     /gene="traW"
                     /locus_tag="LSX49_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HBL7167425.1"
                     /translation="MRCRGLIALLIWGQSVAAADLGTWGDLWPVKEPDMLTVIMQRLT
                     ALEQSGEMGRKMDAFKERVIRNSLRPPAVPGIGRTEKYGSRLFDPSVRLAADIRDNEG
                     RVFARQGEVMNPLQYVPFNQTLYFINGDDPAQVAWMKRQTPPTLESKIILVQGSIPEM
                     QKSLDSRVYFDQNGVLCQRLGIDQVPARVSAVPGDRFLKVEFIPAEEGRK"
     gene            39113..40105
                     /locus_tag="LSX49_000987"
     CDS             39113..40105
                     /locus_tag="LSX49_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HBL7167426.1"
                     /translation="MKRRLWLLMLFLFAGHVPAASADSACEGRFVNPITDICWSCIFP
                     LSLGSIKVSQGKVPDTANPSMPIQICPALPPLFRRIGLAIGYWEPMALTDVTRSPGCM
                     VNLGFSLPAFGKTAQGTAKKDEKQVNGAFYHVHWYKYPLTYWLNIITSLGCLEGGDLD
                     IAYLSEIDPTWTDSSLTTILNPEAVIFANPIAQGACAADAIASAFNMPLDVLFWCAGS
                     QGSMYPFNGWVSNESSPLQSSLLVSERMAFKLHRQGMIMETIGKNNAVCNEYPSPILP
                     KERWRYQMVNMYPDSGQCHPFGRSVTRWETGKNPPNTKKNFGYLMWRKRNCVFL"
     gene            40114..40752
                     /gene="trbC"
                     /locus_tag="LSX49_000988"
     CDS             40114..40752
                     /gene="trbC"
                     /locus_tag="LSX49_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HBL7167427.1"
                     /translation="MKLSMKSLAALLMMLNGAVMASENVNTPENRQFLKQQENLSRQL
                     REKPDHQLKAWAEKQVLETPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPE
                     EGLKRMLGETRHYGIPATLRGMVNNDLKTTAEAVLSLVKDGATDGVQIDPTLFSQYGI
                     RSVPALVVFCSQGYDIIRGNLRVGQALEKVAATGDCRQVAHDLLAGKGDSGK"
     gene            40749..42557
                     /gene="traN"
                     /locus_tag="LSX49_000989"
     CDS             40749..42557
                     /gene="traN"
                     /locus_tag="LSX49_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system mating-pair
                     stabilization protein TraN"
                     /protein_id="HBL7167428.1"
                     /translation="MKRILPLILALVAGMAQADSNSDYRAGSDFAHQIKGQGSSSIQG
                     FKPQESIPGYNANPDETKYYGGVTAGGDGGLKNDGTTEWATGETGKTITESFMNKPKD
                     ILSPDAPFIQTGRDVVNRADSIVGNTGQQCSAQEISRSEYTNYTCERDLQVEQYCTRT
                     ARMELQGSTTWETRTLEYEMSQLPAREVNGQYVVSITSPVTGEIVDAHYSWSRTYLQK
                     SVPMTITVLGTPLSWNAKYSADASFTPVQKTLTAGVAFTSSHPVRVGNTKFKRHTAMK
                     LRLVVRVKKASYTPYVVWSESCPFSKELGKLTKTECTEAGGNRTLVKDGQSYSMYQSC
                     WAYRDTYVTQSADKGTCQTYTDNPACTLVSHQCAFYSEEGACLHEYATYSCESKTSGK
                     VMVCGGDVFCLDGECDKAQSGQSNDFAEAVSQLAALAAAGKDVAALNGVDVRAFTGQA
                     KFCKKAAAGYSNCCKDSGWGQDIGLAKCSSDEKALAKAKSNKLTVSVGEFCSKKVLGV
                     CLEKKRSYCQFDSKLAQIVQQQGRNGQLRISFGSAKHPDCRGITVDELQKIQFNRLDF
                     TNFYEDLMNNQKIPDSGVLTQKVKEQIADQLKQAGQ"
     gene            42584..42841
                     /gene="trbE"
                     /locus_tag="LSX49_000990"
     CDS             42584..42841
                     /gene="trbE"
                     /locus_tag="LSX49_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbE"
                     /protein_id="HBL7167429.1"
                     /translation="MKVIFTSNRFIDFLIRLLITAIVISLVIIWSWDTVKETTADGML
                     AAAFVILYSGVLLFILYFCFSALTDLQKPDERKSDERNEDE"
     gene            42834..43577
                     /gene="traF"
                     /locus_tag="LSX49_000991"
     CDS             42834..43577
                     /gene="traF"
                     /locus_tag="LSX49_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TraF"
                     /protein_id="HBL7167430.1"
                     /translation="MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAA
                     PRQEPDIMQKLAALQTATKRALYEAILYPGVDNFVKYFRLQNYWTQQAGLFTMSARKA
                     MLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQL
                     AQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGS
                     VRPLSYGFISQDDLAKQFLNVSEDFKPNF"
     gene            43591..43932
                     /gene="trbA"
                     /locus_tag="LSX49_000992"
     CDS             43591..43932
                     /gene="trbA"
                     /locus_tag="LSX49_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HBL7167431.1"
                     /translation="MHTGDLCFFTGASLFIVGVVGYFFTGLNNKGVYLLSSFVFFVVN
                     VISVCMLPDNFLFLCGAVMNQCAVPVVSMAVSTMPIITKFDSFRRMFICIMLSAIWSG
                     VMWFFIISLVK"
     gene            complement(43913..44248)
                     /locus_tag="LSX49_000993"
     CDS             complement(43913..44248)
                     /locus_tag="LSX49_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin ArtA"
                     /protein_id="HBL7167432.1"
                     /translation="MEKRSFKEKLEIVRNIIRESLSGNAAFALLVYSLLHTLPIKTFA
                     DLFVTILLFIAIIAVVIWLFLIIYVYFCDLFRSHWIAVWFILWSVVINLTIGFGIYDK
                     LAPVISLMK"
     gene            44329..44613
                     /gene="traQ"
                     /locus_tag="LSX49_000994"
     CDS             44329..44613
                     /gene="traQ"
                     /locus_tag="LSX49_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HBL7167433.1"
                     /translation="MISKRRFSLPRLDITGMWVFSLGVWFHIVARLVHSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSREEREALEARQQAMMAEQQEGGHVSH"
     gene            44600..45154
                     /gene="trbB"
                     /locus_tag="LSX49_000995"
     CDS             44600..45154
                     /gene="trbB"
                     /locus_tag="LSX49_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HBL7167434.1"
                     /translation="MSLTKLLPVILLMMATGVQASTRDEIERLWHPQGMAAQPAQPAA
                     DTPARTDKTEKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYG
                     FSVFPYTLDGQGDMAFPEALPVPPDVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGA
                     TDAAGFMARMDTVLQMYGGKKGAK"
     gene            45084..45458
                     /gene="trbJ"
                     /locus_tag="LSX49_000996"
     CDS             45084..45458
                     /gene="trbJ"
                     /locus_tag="LSX49_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="HBL7167435.1"
                     /translation="MPPVLWRGWIPFCRCTEGKKVRNKQVVLLIAGISGIATGIIVSL
                     NIPFIRQGLFYPASPVEIVVSLCLTFSVSVVFFVGAIVGWISVSEIYYSRMTGLNESS
                     VISEETYNDKKQKESGIQNQKN"
     gene            45412..45804
                     /gene="trbF"
                     /locus_tag="LSX49_000997"
     CDS             45412..45804
                     /gene="trbF"
                     /locus_tag="LSX49_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HBL7167436.1"
                     /translation="MTKNKKNQEFKIRKIRRNIEYSFRGSDRYFYLFIVFLVAGIVLW
                     AVMHVIFDVCIDSWMADPKLLNFQYMWNVLMKVIPFTLWALAARFLVTFFLSPMCELI
                     FGNIMIFLLKRRMRRENTLREGKNDATH"
     gene            45791..47164
                     /locus_tag="LSX49_000998"
     CDS             45791..47164
                     /locus_tag="LSX49_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HBL7167437.1"
                     /translation="MPRIKPLLVLCAALLTVTPAASADVNSDMNQFFNKLGFASNTTQ
                     PGVWQGQAAGYAYGGSLYARTQVKNVHLISMTLPDINAGCGGIDAYLGSFSFINSEQL
                     QRFVKQIMSNAAGYFFDLALQTTVPEIKTAKDFLQKMASDINSMNLSSCQAAQGIIGG
                     LFPRTQVSQQKVCQDIAGESNIFADWAASRQGCTVGGKSDSVRDKASDKDKERVTKNI
                     NIMWNALSKNRMFDGNKELKEFVMTLTGSLVFGPNGEITPLSARTTDRSIIRAMMEGG
                     TAKIYHCNDSDKCLKVVADTPVTISRDNALKSQITKLLASIQNKAVSDTPLDDKEKGF
                     ISSTTIPVFKYLVDPQMLGVSNSMIYQLTDYIGYDILLQYIQELIQQARAMVATGNYD
                     EAVIEHINDNMNDATRQIAAFQSQVQVQQDALLVVDRQMSYMRQQLSARMLSRYQNNY
                     HFGGSTL"
     gene            47161..49986
                     /gene="traG"
                     /locus_tag="LSX49_000999"
     CDS             47161..49986
                     /gene="traG"
                     /locus_tag="LSX49_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HBL7167438.1"
                     /translation="MNEVYVIAGGEWLRNNLNAIAAFMGTRTWDSIEKIALTLSVVAV
                     AFMWVQRHNVMDLLGWAAVFVLISLLVNIRTSVQIIDNSDLVKVHRVDNVPVGLAMPL
                     SLTTRIGHAMVASYEMIYTQPDSFTYSKTGMLFGAELVSKSTDFLSRNPEIANLFQDY
                     VQNCVMGDIYLNHKYTLEELMASNDPYTLIFSRPSPLRGVYDSNNNFVTCKDASVSLK
                     DKLNLDTQSGGKTWHYYAQQLFGGRPDPNLLFSTLIGDSYRYFYDSSKSASQIIRQNV
                     TINALKEGITSYAARNGDSASLVNLATTSSMEKQRLAHVSIGHVAMRTLPMTQTILTG
                     IAIGIFPLLVLAAVFNKLTLSVLKGYVFALMWLQSWPMLYAILNSAMTFYAKQNGAPV
                     VLSEISQIQLKYSDLASTAGYLSMMIPPLSWMMVRGLGAGFSSVYSHFASSAISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATTTQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAAAQQEMAREASNRAESALHGFSSSIASAWNSLSQFGSNRG
                     SSDSVTGGADSTMSAQDSMMASRMRSAVESYAKAHNISNEQATQELASTSTRLSGGMY
                     ADAHAEWGVKPKILGVGGGVGIRGGFKGSLDATDDDSHSASSGSRATHDARHDIDARA
                     TQDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQVQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIDQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSIHGEENIVDRQYSELKNNHKQEEIQQNNRYNEENKR
                     QKLIPTPSEDALKQMVDDKKERLKGPL"
     gene            49983..50492
                     /gene="traS"
                     /locus_tag="LSX49_001000"
     CDS             49983..50492
                     /gene="traS"
                     /locus_tag="LSX49_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003898910.1"
                     /note="TraS, as the term is used in F-like plasmids, is a
                     plasmid entry exclusion protein. It interacts with the
                     F-like plasmid mating stabilization protein TraG; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer entry exclusion protein TraS"
                     /protein_id="HBL7167439.1"
                     /translation="MITHYDIKMEMQKLKEVLSVEGVNIPSLLQVIKPGTYVFLWVLL
                     WPTFLRLVSVKSDVRDVGFDICASGMMGFLLFVAITNGMMLYLAIPDSFRKDSKIINF
                     MYSKSKTYILLFLIVFSMVSFMHSILYVFALMITFILFFLVYTIDINRYNLSAIVSVI
                     GLFKKESVS"
     gene            50506..51237
                     /locus_tag="LSX49_001001"
     CDS             50506..51237
                     /locus_tag="LSX49_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HBL7167440.1"
                     /translation="MKTKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIW
                     LEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKAD
                     KMDLRESQGWLNRGYEGAAVGAALGAGITGYNSSSAGATLGVGLAAGLVGMAADAMVE
                     DVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNAN
                     KVNLKFEEAKPVLEDQLAKSIANIL"
     gene            51489..53687
                     /gene="traD"
                     /locus_tag="LSX49_001002"
     CDS             51489..53687
                     /gene="traD"
                     /locus_tag="LSX49_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001577029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HBL7167441.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILVGLV
                     LWVKISWQTFVNGCIYWWCTTLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLATVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVA
                     RMLKKDDKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARKRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRKRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQTRP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQIASLFEPDVPEVVSGEDVTQAEQPQQ
                     PQQPQQPQQPQQPQQPVSPAINDKKSDSGVNVPAGGIEQELKMKPEEEMEQQLPPGIS
                     ESGEVVDMAAYEAWQQENHPDTQQQMQRREEVNINVHRERGEDVEPGDDF"
     gene            53687..58807
                     /gene="traI"
                     /locus_tag="LSX49_001003"
     CDS             53687..58807
                     /gene="traI"
                     /locus_tag="LSX49_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HBL7167442.1"
                     /translation="MMSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQ
                     GSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSMMAMLGGDKRL
                     IDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHA
                     VVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVV
                     GKHGMWEMPGVPVEAFSGRSQTIRETVGEDASLKSRDVAALDTRKSKQHVDPEIKMTE
                     WMQTLKETGFDIRAYRDAAEQRAYTRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQF
                     TYTDVLARTVGILPPEAGVIERARAGIDEAISREQLIPLDREKGMFTSGIHVLDELSV
                     RALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVA
                     ELAMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQEGMAFTPGSTVIVD
                     QGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKYAGVNTYRWQGGEQR
                     PATIISEPDRNVRYDRLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVL
                     GHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLT
                     LRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASV
                     SEDAMTVVVPGRAEPATLPVADSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMD
                     NATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAISLQ
                     KTGLHTPAQQAIHLALPVLESKNLAFSMVDLLTEAKSFAAEGTGFTELGGEINAQIKR
                     GDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMETLTSG
                     QRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAV
                     GEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIA
                     AGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYSLINR
                     DVEKALSGLESVKPSQVPRLEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDI
                     PMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVP
                     VLNTANIRDGELRRLSTWENNPDALALVDSVYHRIAGISKDDGLITLEDAEGNTRLIS
                     PREAVAEGVTLYTPDKIRVGTGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQ
                     QTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVAL
                     SRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAQRLFSTARELRDV
                     AAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGRSAGIWLNPLTTDDGN
                     GLRGFSGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRE
                     TERRADEIVRKMAENKPDLPDGKTELAVRDIAGQERDRTATSERETALPESVLRESQR
                     EREAVREVARENLLQRLLQQMERDMVRDLQKEKTLGGD"
     gene            58827..59573
                     /gene="traX"
                     /locus_tag="LSX49_001004"
     CDS             58827..59573
                     /gene="traX"
                     /locus_tag="LSX49_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="HBL7167443.1"
                     /translation="MTTDNTNTIRNDSLAARTDTWLQSFLVWSPGQRDIIKTVALVLM
                     VLDHINLIFQLKQEWMFLVGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQF
                     AYYLAGFPWYEGNILFAFAVVAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAG
                     LLMLAVSHRLYRAEDRAERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSC
                     AGKSLPRFWPGDFFPTFYACHLAVLGVLAL"
     gene            59628..60188
                     /locus_tag="LSX49_001005"
     CDS             59628..60188
                     /locus_tag="LSX49_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HBL7167444.1"
                     /translation="MTEQKRPVLTLKRKTEGTAPVRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELAAKKAQARQALSIYLNLPSLDEAVNTLKPWWPGLFDGDTPRLLACGIRD
                     VLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEET
                     YAAERLDKIRRQNRIKAELQAVLDEK"
     gene            60322..60534
                     /locus_tag="LSX49_001006"
     CDS             60322..60534
                     /locus_tag="LSX49_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167445.1"
                     /translation="MNGFRNSSRNGQVWCWQRAGSRAVILEVSGRWMEAAEGWRRAAC
                     VAPRTDWQQFARKRAEHCHRRCRGRV"
     gene            complement(60835..60924)
                     /locus_tag="LSX49_001007"
                     /pseudo
     CDS             complement(60835..60924)
                     /locus_tag="LSX49_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            60979..61656
                     /locus_tag="LSX49_001008"
     CDS             60979..61656
                     /locus_tag="LSX49_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL7167446.1"
                     /translation="MSIIFNGHYRMKHRTWITEALRLHFEEHLPRVVAGRRLGVPKST
                     VCSMFVRFRRAGLSWPLPAGMSEQELDACLYGQFSTVPVVRPESTVISEAPVVKKRPR
                     RPNFPYEFKIALVEQSLQPGACVAQIARENGINDNLLFNWRHQYRKGGLLPSGKNMPA
                     LLPVTLTPEPDNKIPAPAQEPEQINTPSDSLCCELVLPAGTLRLKGKLTPALLQTLIR
                     EIKGSSH"
     gene            61656..62003
                     /gene="tnpB"
                     /locus_tag="LSX49_001009"
     CDS             61656..62003
                     /gene="tnpB"
                     /locus_tag="LSX49_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL7167447.1"
                     /translation="MISLPAGSRIWLVAGITDMRNGFNGLASKVQNVLKDDPFSGHLF
                     IFRGRRGDQIKVLWADSDGLCLFTKRLERGRFVWPVTRDGKVHLTPAQLSMLLEGINW
                     KHPKRTERAGIRI"
     gene            62023..63594
                     /locus_tag="LSX49_001010"
     CDS             62023..63594
                     /locus_tag="LSX49_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL7167448.1"
                     /translation="MDTSLAHENARLRALLQTQQDTIRQMAEYNRLLSQRVAAYASEI
                     NRLKALVAKLQRMQFGKSSEKLRAKTERQIQEAQERISALQEEMAETLGEQYDPVLPS
                     ALRQSSARKPLPASLPRETRVIRPEEECCPACGGELSSLGCDVSEQLELISSAFKVIE
                     TQRPKQACCRCDHIVQAPVPSKPIARSYAGAGLLAHVVTGKYADHLPLYRQSEIYRRQ
                     GVELSRATLGRWTGAVAELLEPLYDVLRQYVLMPGKVHADDIPVPVQEPGSGKTRTAR
                     LWVYVRDDRNAGSQMPPAVWFAYSPDRKGIHPQNYLAGYSGVLQADAYGGYRALYESG
                     RITEAACMAHARRKIHDVHARAPTYITTEALQRIGELYAIEAEVRGCSAEQRLAARKA
                     RAAPLMQSLYDWIQQQMKTLSRHSDTAKAFAYLLKQWDALNVYCSNGWVEIDNNIAEN
                     ALRGVAVGRKNWMFAGSDSGGEHAAVLYSLIGTCRLNNVEPEKWLRYVIEHIQDWPAN
                     RVRDLLPWKVDLSSQ"
     gene            complement(63632..63859)
                     /locus_tag="LSX49_001011"
                     /pseudo
     CDS             complement(63632..63859)
                     /locus_tag="LSX49_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT        15599 a        15616 c        17816 g        14828 t
ORIGIN      
        1 cgcttcctgg ggggttaatg gctgatgacg ataaaatcat atatcgaatg atttatttct
       61 ctgcctgtaa atatcaggcc aggatttatt atgcgattaa tgataaatat catatcatct
      121 gcgggtttcc ctccacgcag gtccggtttc cggcgaaacc ggagcctcat ttttcggcct
      181 gaagttttgt cgttgactac tttttaccgg cttgtgccca gttgagaagc cgctgactta
      241 gtttctgaat ctccgaagat ggctttccgg aataaaatag atgttgcccc gtgcccgtga
      301 gcaggccacg tatagcctgt tacgggatga tggtggaagt gctgccagct tctgttggat
      361 gaggcgcatc cagtggttgg cccccatcac gatgcagacg tcctgaaagt ggtcgagtcc
      421 tttactgccc ccccagttca ttgagtggca tccgtaacgg tgatgttcgc gatagaagag
      481 cttgatcatc gtgttgtccg cgtgcagggc cgctgaacgc gcttcatccg tgacgatttc
      541 aatctgggtg gtatgtgttc catgagccga aatgcgaatg ttcagttgtc cggtaatgaa
      601 ctcacacact gtagctgaac agcgccatgt ccggctgagc gtctcacaat ccaccatgat
      661 acccgcagcc ctgaagcgag cctcgtatcg ggttatgtct tcatgcagcg tagcattgac
      721 gttaccgtcg cggcttgtgt caaaggtatg ctgataaaaa tccccgcagc acagcactga
      781 gatttccgcg cggcatagct ccagcagaaa attaaagtca tggccggcaa agtcctggac
      841 ttcatcaacg aacaactcat cgtagtaacg ggcaagtcgg gtacggatat ctggcagcaa
      901 cccccgggct gtcagcaggt gtgcgagccg ccggtgatac agccgtccgg cgggatcctg
      961 ataatgccgg atattcgtgc gcggtattct ggaagggggc tggttgaagc tcagaccacg
     1021 cgatgacagt tgctcctgca ggaaagggcg aaaacagaaa ccgtgcagaa actcaaacca
     1081 ggtcatcaca cggatcccgt acggtatgta gccaaagcgt ctgataatct gcgcccgcag
     1141 atgtgcttca ttatttacgg tgaaggtcag gatcagcgtc cgccggtcct ctcttaaccg
     1201 acgtatcagc agcgtggttt tacccgagcc ggcaaccgca aatatcactc tcttatccat
     1261 gccagtgcct cctggatata atcaggaacg gtcagctttt cggcgtgcaa ctgtaacagc
     1321 tggaatgctg cttctgcctt attggccagc atgtaatcct gaaccgtgag tgtccggcgg
     1381 gttccgcgga aaagcgcatc acacaggtcg gcattatcct gatacaggca gatttcaaat
     1441 gtggagcggc tgttgtcgtg gtcagcaaat acccgggagc gggaacaaag cacgtcagca
     1501 tagcgttcat cgcaattttg ctgatagttg ccgtcattgt cgcgaagggc cgcgacacga
     1561 ttttccagaa gacgggccag ttcaagataa cgacggaaac tcgttccgcc gatagcgatg
     1621 atgtgaaccc cgtcatcctc cggtgccctg ccatacaggc ggtgataaaa ggcctcgatc
     1681 agaataaact cagcatcccc ctccacgagc agcacgcgtc tggccagcgc aaattccagc
     1741 acgttattat ccggtgcttt catgaagaag gcggcagtct cagcggaaag ttcattcatc
     1801 agtaccggcc gggtagctcc gaggagaata gccttacgta ggtcgaggcg ggaggagata
     1861 tggctactgt gtgtggcaat aaacacctgc gtctgccgtt ccgtggcaag ctgattaacc
     1921 agcctcttca tactgacatg gctgagatga ttctccggct cctcaagcaa cagcgcgtgg
     1981 atctctcccc cctgctgctg atgccgctgc agcgcaaact ccgttttgat gaaacactgt
     2041 cttccttttc cgcggtgacg aatggaaata ccgtcctcag taatgtccag gttcgcctca
     2101 agacctgatt tagcgccgga acgcacgcca aactgatacg ttttcagcgt gtcgtttatg
     2161 gcggacagat gccgggcgca gaagtgcatt ttctgttgcc ggtaactgtt ttcaagccgg
     2221 taccgatcgg ccaccggcac attgacgctg taaactgtgc gcgtatactc ctgtgcggca
     2281 tgctcgttat caatgcgtgc actgtctaag aacagatggc gcagatagcg tctgaagcct
     2341 gcgaaatgac caccggagaa tgtgctgaac tgcacggaat agtattcata gggaaaatta
     2401 tcaggatcct gctgcaaaac atggtgtata tcctgaccgt attcctccat catgggagca
     2461 atgcgcattc tgagaccatc cgcatcgata cccgccagat tttgcctgcc gttcaggtca
     2521 ggctctcccc cattactcag gaaaacgtca gcggtcagca cgggtaactg atcggcacgg
     2581 cgctcacctt cctgaaaatg cctgactgct gactgtgaca ggagcgattc cacccccagc
     2641 gcctcaaccc gatgcctgct gtcactcagc acaaggtcaa gagccagcag aatagtgctt
     2701 ttcccggact cattgtcccc aaccagaatg ttacgatcgt tgctgaagcg caggtccagt
     2761 tccggaaact ttttgaagtt ttgcagcata agccgcgtga tcagtggcat ttttttattc
     2821 ctttatatac cgctgcctga aagagcggcc ggccgcgcct gaccgcctgt tttgttttac
     2881 agcgttatct tacccagtct tccagcacaa gacccggtac ccgctcaaac tctctcacat
     2941 tattcgtcac cagaatggca caggcagcga tggcgtgtcc ggctatcgcc gtgtcgttcg
     3001 gaccgatcgg cgtgccggcg agacgcagtg ccaccttaat ctccgtggtc gcatccaccg
     3061 cggcgcggtc ccacggcagg acggcatcga gcctctcaca gaacgcgtca accagttgca
     3121 cgtggcgtgg cgaggccttc ggaccggtgg caccgaagcg catctcggag taggtgatgg
     3181 ccgagaccac gatacggtga ccgcgcagca ccgactgctc caggtgctta agcaatgctt
     3241 caggttgctc gcgcatgatg aacgagcaga tgttcgtgtc gagcatatag atcttgttca
     3301 caggttaact cgtccttcgt cgctgacaac gtcctcgcgc tccgtcataa agtccggatc
     3361 ggccttttct agctccagga atgagcccca ggtcggccgg acggggcgca gaatgatgct
     3421 gtccccttcc cggacgatct ccagctcgct caccccctca aaatccagat cgcgtggaag
     3481 gcggatagca cggttgttgc catttttaaa aatggatacg gttctcatga ttctctcccg
     3541 ggtaagtgtg gatatgtgat gcatatccgg aatgatgttc attgcaccgg gtgtgtgcat
     3601 atgtttagta taggcagatg tcaggcatat ggatatgttc agcctatgtt attttctctc
     3661 tttccccgtg cagatccggt ttctggtggt tccggatccg cggatccttc gctgccgccc
     3721 gctggtccgc tttcacagga tgtggtgtcc cgctccgctg acatgacact gtatgttgtg
     3781 tttcttcccg tgttcccgag ccagtcatca gcggcagaaa agatcgcttc gcttattcac
     3841 tgatcctgat tcacttccgg aaaatcctga atccgataaa aatcggatca tagaaaaaca
     3901 gtcatcctgt aatttatcat ggttactaca ttgcaggtta ttattgtcat gattactttt
     3961 caggtcagtt attgatggtg gtgttaataa tagctggata acaatattcc gttgccggag
     4021 gcatgttata gcgtaatact ggtgtatact taatggtgta cagagagtat gtaagatgag
     4081 gtgcattatg aagcagcgca ttacagtcac cgtcgacagt gacagctatc agttgctcaa
     4141 ggcatatgat gtcaatatct ccgggctggt aagcaccacc ctgcagaatg aagcccgtcg
     4201 tctgcgtgcc gaacgctggc aggcagaaaa tcaggaaggg atggctgagg tcgcccggtt
     4261 tattgaaatg aacggctctt ttgccgacga gaacagggac tggtgaaatg cagtttaagg
     4321 tttacaccta taaaagagag agccgttatc gtctgtttgt ggatgtccag agtgacatta
     4381 ttgacacgcc tgggcgacgg atggtgatcc ccctggccag tgcacgtctg ttgtcagata
     4441 aggtctcccg tgagctttac ccggtggtgc atgtcgggga tgaaagctgg cgcatgatga
     4501 ccaccgatat ggccagtgtg ccggtctccg ttatcgggga ggaagtggct gatctcagcc
     4561 accgagaaaa tgacatcaaa aatgccatta acctgatgtt ctggggaata taaatgtcag
     4621 gctccgttat acacagccag tctgcagcca tggtaccggc agtgtattct gccggacagt
     4681 ctgcacaact tcctgttgcc attgattatc cggcagctct ggcactccgc cagatgtcga
     4741 tggttcatga tgaactgccg aaatatctgc tggctcccga ggtgagtgcc ctgcttcatt
     4801 atgtcccgga tctgcgccgc aagatgctgc tggccactct gtggaacacc ggcgcgcgta
     4861 ttaatgaagc actagcgctg acgcgggggg atttttcgct cacgcctccg tatccgtttg
     4921 tgcagcttgc gaccctgaaa caacggaccg aaaaagctgc caggacggcg gggagaatgc
     4981 ccgccggtca gcagactcac cggctggttc cgctctctga ctcctggtac gtcagccagc
     5041 tgcagacgat ggtggcaaca ctgaaaatac ccatggagcg gcgtaaccgt cgcacaggaa
     5101 ggacagagaa agcgcggatc tgggaagtga cggacagaac ggtcaggacc tggattgggg
     5161 aggcggttgc cgccgctgct gctgacggtg tgacgttctc tgttccggtc acaccacata
     5221 cgttccgcca ttcctatgcg atgcacatgc tgtatgccgg tataccgctg aaagttctgc
     5281 aaagcctgat gggacataag tccatcagtt caacggaagt ctacacgaag gtttttgcgc
     5341 tggatgtggc tgcccggcac cgggtgcagt ttgcgatgcc ggagtctgat gcggttgcga
     5401 tgctgaaaca attatcctga gaataaatgc cttggccttt atatggaaat gtggaactga
     5461 gtggatatgc tgtttttgtc tgttaaacag agaagctggc tgttatccac tgagaagcga
     5521 acgagacagt cgggaaaatc tcccattatc gtagagatcc gcattattaa tctcaggagc
     5581 ctgtgtagcg tttataggaa gtagtgttct gtcatgatgc ctgcaagcgg taacgaaaac
     5641 gatttgaata tgccttcagg aacaatagaa atcttcgtgc ggtgttacgt tgaagtggag
     5701 cggattatgt cagcaatgga cagaacaacc taatgaacac agaaccatga tgtttggtct
     5761 gtccttttac agccagtagt gctcgccgca gtcgagcgac agggcgaagc cctcgagtga
     5821 gcgaggaagc accagggaac agcacttata tattctgctt acacacgatg cctgaaaaaa
     5881 cttcccttgg ggttatccac ttatccacgg ggatattttt ataattattt tttttatagt
     5941 ttttagatct tcttttttag agcgccttgt aggcctttat ccatgctggt tctagagaag
     6001 gtgttgtgac aaattgccct taaccctgtg acaaattgcc ctcagaagaa gctgtttttt
     6061 cgcaaagtta tccctgctta ttgactcttt tttatttagt gtgacaatct aaaaacttgt
     6121 cacacttcac atggatctgt catggcggaa acagcggtta tcaatcacaa gaaacgtaaa
     6181 aatagcccgc gaatcgtcca gtcaaacgac ctcactgagg cggcatatag tctctcccgg
     6241 gatcaaaaac gtatgctgta tctgttcgtt gaccagatca gaaaatctga tggcacccta
     6301 caggaacatg acggtatctg cgagatccat gttgctaaat atgctgaaat attcggattg
     6361 acctctgcgg aagccagtaa ggatatacgg caggcattga agagtttcgc ggggaaggaa
     6421 gtggtttttt atcgccctga agaggatgcc ggcgatgaaa aaggctatga atcttttccc
     6481 tggtttatca aacgtgcgca cagtccatcc agagggcttt acagtgtaca tatcaaccca
     6541 tatctcattc ccttctttat cgggttacag aaccggttta cgcagtttcg gcttagtgaa
     6601 acaaaagaaa tcaccaatcc gtatgccatg cgtttatacg aatccctgtg tcagtatcgt
     6661 aagccggatg gctcaggcat cgtctctctg aaaatcgact ggatcataga gcgttaccag
     6721 ctgcctcaaa gttaccagcg tatgcctgac ttccgccgcc gcttcctgca ggtctgtgtt
     6781 aatgagatca acagcagaac tccaatgcgc ctctcataca ttgagaaaaa gaaaggccgc
     6841 cagacgactc atatcgtatt ttccttccgc gatatcactt ccatgacgac aggatagtct
     6901 gagggttatc tgtcacagat ttgagggtgg ttcgtcacat ttattctgac ctactgaggg
     6961 taatttgtca cagttttgct gtttccttca gcctgcatgg attttctcat actttttgaa
     7021 ctgtaatttt taaggaagcc aaatttgagg gcagtttgtc acagttgatt tccttctctt
     7081 tcccttcgtc atgtgacctg atatcggggg ttagttcgtc atcattgatg agggttgatt
     7141 atcacagttt attactctga attggctatc cgcgtgtgta cctctacctg gagtttttcc
     7201 cacggtggat atttcttctt gcgctgagcg taagagctat ctgacagaac agttcttctt
     7261 tgcttcctcg ccagttcgct cgctatgctc ggttacacgg ctgcggcgag cgctagtgat
     7321 aataagtgac tgaggtatgt gctcttctta tctccttttg tagtgttgct cttattttaa
     7381 acaactttgc ggttttttga tgactttgcg attttgttgt tgctttgcag taaattgcaa
     7441 gatttaataa aaaaacgcaa agcaatgatt aaaggatgtt cagaatgaaa ctcatggaaa
     7501 cacttaacca gtgcataaac gctggtcatg aaatgacgaa ggctatcgcc attgcacagt
     7561 ttaatgatga cagcccggaa gcgaggaaaa taacccggcg ctggagaata ggtgaagcag
     7621 cggatttagt tggggtttct tctcaggcta tcagagatgc cgagaaagca gggcgactac
     7681 cgcacccgga tatggaaatt cgaggacggg ttgagcaacg tgttggttat acaattgaac
     7741 aaattaatca tatgcgtgat gtgtttggta cgcgattgcg acgtgctgaa gacgtatttc
     7801 caccggtgat cggggttgct gcccataaag gtggcgttta caaaacctca gtttctgttc
     7861 atcttgctca ggatctggct ctgaaggggc tacgtgtttt gctcgtggaa ggtaacgacc
     7921 cccagggaac agcctcaatg tatcacggat gggtaccaga tcttcatatt catgcagaag
     7981 acactctcct gcctttctat cttggggaaa aggacgatgt cacttatgca ataaagccca
     8041 cttgctggcc ggggcttgac attattcctt cctgtctggc tctgcaccgt attgaaactg
     8101 agttaatggg caaatttgat gaaggtaaac tgcccaccga tccacacctg atgctccgac
     8161 tggccattga aactgttgct catgactatg atgtcatagt tattgacagc gcgcctaacc
     8221 tgggtatcgg cacgattaat gtcgtatgtg ctgctgatgt gctgattgtt cccacgcctg
     8281 ctgagttgtt tgactacacc tccgcactgc agtttttcga tatgcttcgt gatctgctca
     8341 agaacgttga tcttaaaggg ttcgagcctg atgtacgtat tttgcttacc aaatacagca
     8401 atagtaatgg ctctcagtcc ccgtggatgg aggagcaaat tcgggatgcc tggggaagca
     8461 tggttctaaa aaatgttgta cgtgaaacgg atgaagttgg taaaggtcag atccggatga
     8521 gaactgtttt tgaacaggcc attgatcaac gctcttcaac tggtgcctgg agaaatgctc
     8581 tttctatttg ggaacctgtc tgcaatgaaa ttttcgatcg tctgattaaa ccacgctggg
     8641 agattagata atgaagcgtg cgcctgttat tccaaaacat acgctcaata ctcaaccggt
     8701 tgaagatact tcgttatcga caccagctgc cccgatggtg gattcgttaa ttgcgcgcgt
     8761 aggagtaatg gctcgcggta atgccattac tttgcctgta tgtggtcggg atgtgaagtt
     8821 tactcttgaa gtgctccggg gtgatagtgt tgagaagacc tctcgggtat ggtcaggtaa
     8881 tgaacgtgac caggagctgc ttactgagga cgcactggat gatctcatcc cttcttttct
     8941 actgactggt caacagacac cggcgttcgg tcgaagagta tctggtgtca tagaaattgc
     9001 cgatgggagt cgccgtcgta aagctgctgc acttaccgaa agtgattatc gtgttctggt
     9061 tggcgagctg gatgatgagc agatggctgc attatccaga ttgggtaacg attatcgccc
     9121 aacaagtgct tatgaacgtg gtcagcgtta tgcaagccga ttgcagaatg aatttgctgg
     9181 aaatatttct gcgctggctg atgcggaaaa tatttcacgt aagattatta cccgctgtat
     9241 caacacagcc aaattgccta aatcagttgt tgctcttttt tctcaccccg gtgaactatc
     9301 tgcccggtca ggtgatgcac ttcaaaaagc ctttacagat aaagaggaat tacttaagca
     9361 gcaggcatct aaccttcatg agcagaaaaa agctggggtg atatttgaag ctgaagaagt
     9421 tatcactctt ttaacttctg tgcttaaaac gtcatctgca tcaagaacta gtttaagctc
     9481 acgacatcag tttgctcctg gagcgacagt attgtataag ggcgataaaa tggtgcttaa
     9541 cctggacagg tctcgtgttc caactgagtg tatagagaaa attgaggcca ttcttaagga
     9601 acttgaaaag ccagcaccct gatgcgacca cgttttagtc tacgtttatc tgtctttact
     9661 taatgtcctt tgttacaggc cagaaagcat aactggcctg aatattctct ctgggcccac
     9721 tgttccactt gtatcgtcgg tctgattatt agtctgggac cacggtccca ctcgtatcgt
     9781 cggtctgatt attagtctgg gaccatggtc ccactcgtat cgtcggtctg attattagtc
     9841 tgggaccacg gtcccactcg tatcgtcggt ctgattatta gtctgggacc acgatcccac
     9901 tcgtgttgtc ggtctgatta tcggtctggg atcacggtcc cacttgtatt gtcgatcaga
     9961 ctatcagcgt gagactacga ttccatcaat gcctgtcaag ggcaagtatt gacatgtcgt
    10021 cgtaacctgt agaacggagt aacctcggtg tgcggttgta tgcctgctgt ggattgctgc
    10081 tgtgtcctgc ttatccacaa cattttgcgc acggttatgt ggacaaaata cctggttacc
    10141 caggccgtgc cggcacgtta accgggctgc atccgatgca agtgtgtcgc tgtcgccggc
    10201 ctcctcaccc ggtcacgttt cgtcgttcct cctccacgcg ctgcggcttc ggggccgcac
    10261 ctgcattcgt atgcggtcgc ccggttacag gtgcggcacg gcctgatgga ggccgcatgt
    10321 gagaggagaa ttcccatgcc aaactggtgc tcgaatcgta tgtatttttc tggtgaaccg
    10381 gcacagatcg ctgagattaa acgactggcc agcggtgcag tcacaccact ttatcgccgc
    10441 gccacaaatg aaggtattca gctgtttctg gccggaagtg ccggacttct gcagaccact
    10501 gaagatgtgc ggtttgaacc atgccccgga ctgacggctg ccgggcgtgg cgttgtatcg
    10561 ccggagaata tcgcgttcac ccgctggctg acacacctgc aggacggtgt actgctggat
    10621 gagcaaaact gcctgatgct gcatgaactc tggctgcaga gcggtactgg acagcgtcgc
    10681 tgggaaggat taccggacga tgtcagggat accatcaccg cacttttcac cgcaaaaaga
    10741 ggtgactggt gtggcttctg gagtaacgag gctgtatcgg tgtggtggaa ccgtctgtgt
    10801 gacaacgtac tgccggaaaa aaccatgccg tttgacctgc tgacggttct gcccacccgc
    10861 ctggatgttg aagtgaatgg ctttaacggt ggtgttctga acggtgttct ttctgcatat
    10921 cactggtata cggaacagta tggcgtgaag tggcctgtgg ggtatgaggt gaatatcagc
    10981 agtcagggag acaacttcat tcaggtggat ttcgacacgc cgtggtgtca gccggaaagc
    11041 gacgttattg cagaattaag ccgccgtttc agctgcacaa tggagcactg gtatgccgaa
    11101 cagggctgca atttctgtgg ctggcagcga tatgagcgtg gcgagcttgt tgatgtgctg
    11161 tggggggagc tggaatggtc ttccccgaca gatgacgatg agctgccgga agtcaccgga
    11221 cctgcgtgga tagtcgacaa tgtggcgcat tatggcggat gaagtatgac ggagacgggc
    11281 gggcaaccgc ccgtttcttt tccggtaaag gatgtcgccg ggctcctctt tttactgcgc
    11341 cggctgacgc ggcgcggcag gaacgctgcc tgtggtcagt gtcccgcgtc cggtgggcac
    11401 gggacgggcg cttttaccgc tcccggctgg caccggtgac agtgtacgcc agcccgtcgc
    11461 ccttttctga tgaacgccct tcaagccgct ttcgcggcat agccttgccg tcagaaagac
    11521 gacggctgcg gtattccacg gtcggcctga cccgttaccg gacgcggtga acagcccaca
    11581 ggcagcgggg aacgggcacc acaggggtgc cctcccggtg tcctctgtaa gagaaggagc
    11641 gttgttatgt cccgttttgt cctcggtaac tgcatcgatg ttatggcccg tattcctgat
    11701 aacgccattg atttcatact gactgacccg ccgtacctcg tcggttttcg tgaccgtttc
    11761 gggcgcacca tcgccggcga taaaaccgat gaatggctgc aaccggcctg taatgaaatg
    11821 taccgcgtac tcaaaaaaga cgcgctgatg gtgagcttct acggctggaa ccgcgtcgat
    11881 cgctttatgg ccgcctggaa aaatgcggga ttcagcgttg ttggtcacct ggtcttcacc
    11941 aaaaactaca catcgaaggc cgcatatgtg ggctatcgcc acgaatgcgc ctacatcctg
    12001 gcaaaaggcc gtccacgtct gccacaaaac ccgctgccgg acgtgctggg ctggaaatat
    12061 tcgggcaatc gtcatcaccc gacggaaaag cccgttacca gcctgcaacc gctgattgag
    12121 agcttcacac acccgaacgc aattgtgctg gacccgtttg caggcagcgg ctcaacctgc
    12181 gtcgttgccc tccagtccgg acgccggtat atcggtatcg agctgcttga acagtatcac
    12241 cgtgccggac agcaacgact ggccgccgtg caacgggcca tgcagcaggg ggccgcgaat
    12301 gataactggt ttgaaccgga ggctgcgtaa atgaactatg ccggacacga aaaacttcgc
    12361 gccgacgtgg cggaggtggc caacaccatg tgtgaccttc gggccaggct gaacgatatg
    12421 gagcatcgct gtcgctttga ttccgatgtg cttgttgaac gcctgacacg ccagacgctg
    12481 tatcgcgcca atcgcctgtt catggaggcg tataccgaaa ttctggaact ggattcctgc
    12541 ttcaaagatt gagaaggaga cgagaatgta cggaacatgc gaaacgctat gccgggagct
    12601 ggcagcaaag tatccgggaa acacgccgct gatgctgctt atctggtccc cggaagagat
    12661 tcaggccctc gctgacggaa tggatatttc tctgtccgat catgaaatca gaaccgtcct
    12721 ggcgcgcctg gaggacatcc cggaagacca gcggactgaa tccggtattt cttccggtgc
    12781 ggcgatggag attatcaata acgtgagaga aaaccgccag gtgaccgtcc ctgctgaact
    12841 gctggcgtcc ctgattcaga ccgccgaaca ggcactgtgg aaacgtgagt gggccgcccg
    12901 tgataacggc ctcgccgtcc cggaatgcgt cacccgccga caggcggtgg ttaatcaggc
    12961 ccgcgccctg ctgaaaaaca acacacgcga aaacgactga tgttatcgcc gcctgcgggc
    13021 ggcgattcag ggagaccatg aatcatgaac gaaacgctga atgcactgat ttatcgccac
    13081 gccagcaacc tgctgctggc gcagggctgg ccggaagaga cggatgttga ccagcgtaat
    13141 ccgaagtatc cgggctggat cagcatttac gtgcggctgg atgtgccccg gctggcgacg
    13201 ttacttatca accgtcacgg cggcgtactg ccgccgctcc tggcctccgc cattcagaaa
    13261 ctgaccggaa ccggggcgga actggtactg tccggcagtc agtggcagtc gctgccggta
    13321 cttccggcag acggaacaca ggtgtttttc ccgtatgccg gagaatggct gaccgaagac
    13381 gaaatcaggg cagttcttga tgcagtgcgc aatgcagtac gaagcatctg ttaccaagtg
    13441 gcagaagatg cccggcgtat ccgggcggcg ctgaccacca ccggtcagac gttgctgacc
    13501 cgccagacgc gccgctttcg tctggttgtg aaggaaagcg attacccctg ctggcttgat
    13561 gaagatgacg aaaatctgcc cgtggtgctc gatgccattc tgaaccgtgg cgctcgtttt
    13621 tcgtcggtgg aaatgtatct ggtcagtgag tgtgtggagc atatcctgtc cagtgggctg
    13681 gcctgcgatg tgctgcgtat acctgatgaa ccgtcccgtc gctggtttga ccgggatatt
    13741 ctgcgggaga tggtcctgga agcccggact gaaatccgca gcatggcgga tgcactggcg
    13801 aaaatccgga aatgatgacg ctggcgggga aaatctccgc cttttccagc cggtccccgg
    13861 aaagagcaaa aggatgtcgc cgcaggctcc gctttacccg gccatgcggg gcatggcctt
    13921 gtgggttttc agttatgtgg cctcagcgtc gtgtgcgggc tgtgccgtgc ctccatcgta
    13981 gccgggcttc tgcgggcggg ttgcaaggta aggtgaaccg ctgcggtcac ccggtccctc
    14041 cttcccgtct gccgtgattt tccggtcgtt cacccgctca gatttcgcgg tctcaccctc
    14101 caactcccgt cagccgtgcg cgtcaggctg cggcttccct tgcgcccttg caaccctgca
    14161 ggcccggcaa agatggaggc acggcaccgc ccggtgtcgc ggaatatgtg aacaacggag
    14221 gaaatcccat gcagtatgcg aaacctgtca ctctgaacgt tgaagagtgc gaccgtctgt
    14281 cttttctgcc ttacctgttt ggcctggatt ttctgtatgc cgaagcgtct gtatacgcgc
    14341 tggcgaaaaa aatgatgccg gaatatgaag gcggattctg gcacttcatc cgcctgccgg
    14401 acggtggcgg ttacatgatg ccggatggcg accgttttca tctggtcaac ggtgaaaact
    14461 ggtttgaccg taccgtgagt gctgatgccg caggcatcat tctgacttcc cttgtgatta
    14521 accgccagtt gtggctgtac cacgacagcg gggatgcagg gttgacacac ctgtacagga
    14581 tgcgcgatgc gcagttgtgg agccacatcg aatttcaccc cgaatgcaac gcgatttacg
    14641 cggcactgga ctgattaacg gacggggcgg caatgccgcc cctgtaaagg agacgagaac
    14701 atgtactgta ctgttaaaga aatcatccgc gatgtactgg atacagacgt gccggacagt
    14761 gaatgcgttt ttgccgtggt gctgacccgt ggggatgtgc gccacatagc ccaggactgg
    14821 aacctgtcag acgatgagct ggaaaccgtc atgcagcggc tggacgatgc ctttgaatat
    14881 ggtgcggatg tcagcattgt tcacgacgtt gttcgtgagc tgatggaaga aaagcgtgcc
    14941 agccgtcagg tgacagttcc ggcggtgatg ctggaaaaag tgatggcgct ggcaggcagt
    15001 gaaatgaagc gcctgtatgc cgtcgggagt gagaacgggg gcgacggtga tgcgttcgtc
    15061 agggaggaac gcgaagcaat ggacgttgtg ttacaggcgc tggacgggga gcacatgtca
    15121 tgaatatcag cacagaaacc cgcgaaattc tgcgcaatta caaagccgtg attaatgcgc
    15181 gacgtcgtga aatggggcag aaaccgctca ccaccgcgca gattgttgat gaaatctgcg
    15241 attttgtggc gaatcagcag gctgttttcc tgggcggtca ctacatctta cagggcagca
    15301 gaaacaggtg atacagggca ggcggtgaag gccgcctgtc agcccgcgcg aaaacccctg
    15361 gcaggctgac gcctgccgga agggaagcgg gccacgctgg cgcgtcgccc gttacccttc
    15421 ccgtctgtga tgtgtctgac tcaggagtgt ttctttctta tgttatggaa ctgttcctga
    15481 tgttgttgtt cctttatctg ctgctctgat tctgactact gcagtgttgt tctgtctgcc
    15541 gggcgcacct tcggctcccg gctgcctggc ggcatccggt cgtcaggccc gactccgaca
    15601 ggcagctgct ggcgcacctg ccagtctccg ccgaacccgc tggcgcggtt tcgggctgtc
    15661 gctacggtcc gatgcgtgaa aaccacaggc ttgcagcgac cgttccggtc gcgccgcctc
    15721 tgtcgcgccg tggcctgcgc tcccggcatc ccggcaaaag gccgccggga tgtaaggcgc
    15781 aacgccgttt cgcgcacgcg ctctccgtcg ttgcggcggg tccctgctca ttgcctgccg
    15841 ggtgccacac acccgtatga gtccctgtcg ccgggggctg atacagccac aacctgccgc
    15901 actgactgtc tagggtaaat gaacagccca caaaattttt tacccaaaac ccggtaaaaa
    15961 attttgcgtt ctgcccagga caggtgcgtc aggccgtggc agtgatgccc cttgcggcga
    16021 aggttctcaa acgggtgaag ttcataccac agggaataca gcagcaggtt cccgcgaaac
    16081 gtcaaaaccg cggctcccga aactcaacgg gtgatgttct ttaaaaatca ggatttattt
    16141 caggctccgg caatatgcat ttatttgttc tgtcagtcat ccggctggca ggtaatgaga
    16201 acgcaggaac agaaggagga aaacaccgga gaacgtcaga cgcagatatg aaaaaagcag
    16261 gtcagggacc tgcttaatcc acaccgcaaa aactgttcgc gcagtttctg cggttccatt
    16321 caacagtcat aaggatgcat ttatgacagt aagtattgtt tcaccttccg cagcggctgt
    16381 aaagccccgc cgtcatcccc gtttcagacg cgaagacatc cccgcgccgg aaattgaccc
    16441 cgtgctgaaa gccttcgggc gacacattgc ccggagtttt caccgggggc gtggtgtaca
    16501 catccccgcc atgaaaaaca cggccttcgg gcaggtgctc cgcacactcg aactgaaacg
    16561 cgcttttaac tgatgaggtg agccgccccg tgaggggcgg caacagacgg aaggagaaca
    16621 ttttatgaca tcagcagcaa tcaccatgac cgccccggaa gccgccagcc ctgtgcagat
    16681 gtaccgcgcg acctactcac cggatgacaa caaactgcgc ctgtatgccg tgtcacgtct
    16741 tgacccggag acgtataaaa aagtgcatga tgccggtttc cgctgggcac caaaacaggc
    16801 gctgtttgtc gcgccagcct ggacaccggg ccgggaagac gtgctcctct cacttgccgg
    16861 agagattgag gatgaagaca gcacgctcgc tgaacgtcag gaagcacggg cggagcggtt
    16921 taccggatac agcggaaagc gggccagtga atccgcacag gcacttgatg aagtggaaag
    16981 actggccgcg atgatcccgc ccggtcagcc cattcttgtg gggcatcaca gcgaacgccg
    17041 cgcccgtcgt gatgcgcagc gtattgaaaa cggcatgaaa cgagccgtga tgctctttga
    17101 acgtgcggaa tactgggaag agcgggcgcg gtcggcactg cttcacgcga agtataaaga
    17161 acgtccggac gttcgctggc gtcgtatcaa aaaaatcgaa gctgatttgc gcaaggctga
    17221 aaagaccatc gcgcagtcgc agaaatatct gacgatgtgg cgggctgaat cgctggatct
    17281 gaatatggca aaactcatca gcagtcatga ccatatcagc gcctgtttcc cgctggatac
    17341 gtatccgcgc ccggcagaaa aaagccagta tgaaggaagt cgatcgttat ggtcggccct
    17401 ggatgatgac atcatcacca cggagcaggc ccgcgaaatt gcgatccgct gtcatgagcg
    17461 gcagattcag catcaacaac gctgggttaa ccactatcag aaccgcctga tctatgagcg
    17521 tgccatgctg gacgaaagcg gcggcgtggt tacccggaca caggattttg agccgggcgg
    17581 acaggttttc agccggggcg agtggctgac catcatccgt gtgaacaaaa gcaacggggc
    17641 ggtgagttca gtcacaacgc caaattacag ttttcttggg tacagcggca cgatgaaagt
    17701 gacgcccgat cgcatcacgg actacaaagc accatcggca gaagaggctg ccgtcgccag
    17761 tcaggccgcg aagcgtccgc cggtagtcaa ctatccgggg gaaggtttcc gggaaatgac
    17821 aaaggcacag tgggccgccc tgccccggga ctgtaaggcc gtgcgtagtg tggcagaagc
    17881 agaagaccac ggggcatacc ggtaccgccg cacaatggac aataatttcc gcctggtgaa
    17941 tgtgtatatc accgacatga aaatcacgga aatcccacag aaataaggta tatccccccg
    18001 ggaaaatccc cgggggatga cggagataat gatatgcaca gtcagttaag agaacgtatc
    18061 cggctgatgc gcgcaaggct ggataacgcc gcgccggttg ctgaaatccg ggctgaatct
    18121 cagctttttg tgactcctgc cccggtctgt gatcgcctgg tgatgctggc ggagatcagc
    18181 aaccgtgatt acattctgga accctctgcc ggcaccgggg ccatactgcg ggcgattcgg
    18241 gataccgcgc cgggggccat gtgtgatgcg gtggaaatca acagcgggct ggttcggtat
    18301 ctgcgggaaa attttaacgg tgtcaggggg ttcagtgtgg cgacttcatg gaatggcagc
    18361 cggtgcagta ttacagccgg gttatcatga atccgccgtt cagccacggg caggatatcc
    18421 ggcatatcct gcgggccttt tccctgttgc gtccgggtgg cgtgctggtc gccgtctgtc
    18481 tcaacggacc acgccagcag gagaagctgt taccgttttc tgacgtccgc gaggagctgc
    18541 cgcgcggcac gtttgcttat accgatgtcc cgacgatgat tattcgtctg cgtgcctgat
    18601 gacacagggc cggcgggagg ataaatgcct gtctgcccgc gccgggaaaa aacgcgcgcc
    18661 ggtggcgctg aaaggggccg cgctcacgcg ccgccccttt cattacgcgg acgttctgat
    18721 gggggcttct gtttcttcat gcctgtcatt tgtctgttac tgatgttgtt gttcctgcta
    18781 ctgctactgc tactgctact gctactgcta ctgttcttct ttttcctgct gctctgattc
    18841 tgactactgc agtgttgtcc tgtctgccgg gcgcaccttc ggctcccggc tgcctggcgg
    18901 catccggtcg tcaggcccga ctccgacagg cagctgctgg cgcacctgcc agtctccgcc
    18961 gaacccgctg gcgcggtttc gggctgtcgc tacggtccga tgcgtgaaaa cccctggctt
    19021 gcagcgaccg ttccggtcgc gccgcctctg tcgcgccgtg acctgcgctc ccggcatccc
    19081 ggcaaaagac cgcgggatgt aaggggcaac gccgtttcgc aaaccgcgct tcacgtcgtt
    19141 gcggcgggtc cctgcccgtt gttctgtccg gtgccattca cctgtttaag cccctgtcgc
    19201 cgggggctga tacagccaca accgtctccg ccagtccagg ggtgaaatgt acatcccgca
    19261 aaactttttg cccagaagca ggcaaaaact tttgcggtct gcccccggac agtcgtttcc
    19321 ggccgtggca gtgatgcccc ttgcggcgaa ggttctcaaa aaggtgatgg tgaataccgg
    19381 agggaacaaa aggcaggtcc ccgcaaaacg tcaaaaccgc ggctcccgaa actcaaaaga
    19441 tgatgggggc tgaaaacatc aacagaagga ggcacatcat ggcagttcgt ggcattaaca
    19501 aggtcattct cgtgggagtg cgccgttgaa gcgcggtgtt ttatggagtg ttgcatgaaa
    19561 agcaacatgg cttagtggta tagccattgc atactgtggt tagcctcgct tggtaacagg
    19621 ctcggagatc ctgaaaagga gaggtgaaca tagcatccac agaaaagggt ggtgaatacg
    19681 gaaatcgtta taagtatcac cactcaatgc aagatgtata tggataaact gggtttgttg
    19741 aagtcgagat ctatgtggga aacaggaaac caataacgca gaacgattga agcgttattc
    19801 ccgtaatagc acaagaaatc cgccctacgt tgattgtgac cactctaacg ggccagctat
    19861 tgatgaaata gttaaacgat cgaaagacat cctaagtaca tcgcatctcc acaccgtgaa
    19921 actacgggac tacctaaact ggatttatac ccagcatggt agcggagtct ccatagtact
    19981 caaggtcggc ctgtaatggg ctacggcagt ccgcattata cggaagcagc aaaggtataa
    20041 atcaaccgga agggagatga aagcctcaca gtgctgcggg gaagggagac agttgttaga
    20101 tacatcaatc tctaagagga gggttagcca atgctgcctg atgaacttga gaaaagatta
    20161 gatggaattg aggatgcttc aaaaaaaggg tatccagtac gtaatctata caaaattgcg
    20221 tgtgagcccg gactgtggct gcaagcctac gtgaatatac gggccaatgc aggtgcactg
    20281 actcaaggtg tatcaacaga taccattgat ggcttctcta tcgaaagagc agagaagctg
    20341 gcaaaaacat tgcggagtag agaatacgta gcgaaacctg tacgcagagt tcagatccca
    20401 aaaaaggacg gaaaaaccag accgctgggg attccaggtg gagacgataa actggcgcaa
    20461 gaagtagcaa gaattattct ggaaagggtt tatgaaccag tattctctga acactctcat
    20521 ggattcagac caaaacgttc gtgtgaaact gcgctcagat ctattcgtcc agtctggaac
    20581 ggagttaaat ggatcgtgga tgttgatatc aaaggtttct ttgacaatat cccccacaaa
    20641 ctattgctga atacactggc agagaaaatt aaggataaga atttcctgaa attaatcgaa
    20701 cagtggctga aggcaggata tgtggacaat tggaaatacc atcgctcata ttctggcacg
    20761 ccacaaggtg ggataatttc tcccttactg gcaaatatat acctcgacaa actggaccgt
    20821 tttgtagaac agaacttaat tcctgcatat acaagcggta caaaacgaag agcgaatcca
    20881 gatatgaaca ggctggccca taagattcat aaactacgaa agaaagtaga cggtatggca
    20941 actgattctg aatcagaaaa agaagccata aagaaagaaa ttgaacgact gcttgaagaa
    21001 aaacgttcta taccatctca ggtcatgaac gatccaaact tcaggcgtat gtactatgtt
    21061 cgatatgctg atgacttcgt aattggtgtc atcggctcga agaaagatgc tgaacatata
    21121 tcaagacagg tcagaaactt tattactact tcactgggat tggaagttaa tgaagcaaag
    21181 accaggatcc gccatatctc agaaggagtt aattttttag gctatgaaat cagacaggca
    21241 gatgcaaaga aattgctgaa gcagaaaatg caagggcggc acgctctccg gagatccacc
    21301 acaggaattg tgcagctctt cgttcctgac aatatagccg ctaaattttg tcaccaaaag
    21361 aaatatggct gttatgagaa tgtgaaggct gtacatcgtt caagtctaca aaatctcagt
    21421 gaagctgaaa ttgttctgac tttcaacgcg gaaatgcgcg gattggcgaa ctactacagt
    21481 ctggcgctgg acatgaaata taaattatca aaattatatt tcatatggca aataagcctt
    21541 tttaagaccc tagcgaataa acgacgtagt tcagtgaata aagtcgccaa atcgctacgg
    21601 caaaataatg gagatctggc tattaccgtt caggccaaaa atggatcccg aaagattgag
    21661 gttttcaaac tcaaacatgt caatcgcaac cgaacaacga ttgtcgatac ggaaccgaga
    21721 accgcacata tcacaacccg cacaacagag atcatgcgtc gattaggggc aaggatctgc
    21781 gagtattgtg cgaagactgg gcgctgcgaa gtacatcatg tcagaaagct aaaagacctg
    21841 aagaaaggtc gtaaggccgg atataaaccc agcctgtggc aactaatgat gatcgcacgc
    21901 cgccggaaaa cgatgatttt gtgcgcaagt tgccacgaca agttacatag cggaaaacta
    21961 cccgatctga gacaggaaaa gggaagaata ctcctgcaac cacctgtctc aagtggggat
    22021 tctgctaaat gagtttatcc ccaataagct agcaatggag agccgtatgc attgaaaggt
    22081 gcacgtacgg ttcggagggg gggtaacggt gatctaactc aagataagca ggacatattc
    22141 gccatttatc ttgaaagacc acacgtaccc taccctaccg cctgggaaaa gatccggaag
    22201 tccgttacat ccccaacggg ggcgcagtgg caaacctgca ggtcgccacg tcggaaacct
    22261 ggcgtgacaa acagacaggg gagatgcggg agcagacaga atggcatcgc gtggtgctgt
    22321 tcggcaagct cgcggaagtg gctggcgaat atctgcgcaa gggcgcgcag gtctacatcg
    22381 aaggtcagct tcgcacccgt agctgggagg ataacggtat cacccgttac gtcaccgaaa
    22441 ttcttgttaa gaccacgggc accatgcaga tgctgggacg tgccgcaggt gctcagactc
    22501 agccggaaga ggggcaacag ttcagcggtc agcctcagcc ggaaccacag gcggaggccg
    22561 gtacgaaaaa aggtggcgca aaaacgaaag gccgtggacg taaggccgcg cagccggagc
    22621 ctcagccgca accgccggag ggtgacgatt acgggttttc agacgatatc ccgttctgat
    22681 cgggctgact gtgataaccg ccccgccccg ccccgttctg tgcggggcat caccggagag
    22741 atgaggatga gcgaatattt cagaatactt caggggctgc ctgacggtcc ttttacccgc
    22801 aaacatgccg aagctgttgc cgcacagtac cggaacgtct ttatcgagga tgaccacggc
    22861 gaacagtttc gcctggttgt ccgtaataac ggtgcaatgg tctggcgtac ctggaatttt
    22921 gaggacggtg ccgggtactg gatgaaccat gtcatcaggg atttcgggat tcttaagtaa
    22981 gagaggtgcc cgacgcgcga acgtccgccg cagattatcg cagccctgaa taaggcaggg
    23041 ctgtccggtg ccgcacggga cgcggagaag atgaagaaag gtgatgcggc tgaacatgca
    23101 gagcaccata tgaaagacaa ccgctgggtt ccaggctgga tgtgtgcacc acgcccacag
    23161 acggatgcca ctgaacgcac cgataacctg gctgatgccg cctgatgaac aaccacaccg
    23221 ccccgccgga gacggggcgg cagcaaggga gataccgtga tgaaaactga actgaccctg
    23281 aatgtattac agaccatgaa cacacaggaa tatgaagata tccgggctgc cggaagtgat
    23341 gaacgccgtg agctgactca cgccgtgatg cgggagcagg atgcgccgga taactggacg
    23401 atgaacggcg agtacggcag cgagtttggc ggctttttcc ccgtccaggt ccgtttcacg
    23461 cctgcccacg aacgttttca cctggcgtta tgttcaccgg gcgatgtctc tcaggtctgg
    23521 gtgctggttc tggtgaatgc cggtggtgag ccgtttgcgg tggttcaggt acagcggcgg
    23581 tttgcaccgg aagctgtcag ccattcactg gcactggcgg cgtcactgga cgcgcagggg
    23641 tacagcgtca gtgacatcat ccatatcctg atggcggaag gaagtcaggc atgagcgcac
    23701 gttcacaggc actggttcct ctcagcacag agcaacaggc cgcatggcgg gcggtggcgg
    23761 agaccgaaaa acgccgccat cagggtaaca cgctggctga atatccgtat gcgggggcgt
    23821 ttttccgctg tctgaacgga agccgcagga tatcgctgtc tgacctgcga tttttcatgc
    23881 cgtccctgac cgcagaagaa ctgcacggca accgtcttca gtggctgtat gccatcgatg
    23941 tgctgattga aacacagggc gaggtttgcc tccttcccct tccaggcgat gcagcagaac
    24001 gcttgttccc gtcggtgcgg tttcgtgtca gggaacgcag tcgccataaa tccgcgctgg
    24061 tcatgcagaa gtacagccgc cagcaggcga gggaggcaga gcagaaagcc cgtgcgtacc
    24121 aggcgctggt cgctcaggct gaaatcgaac tggcattcca ttcgccggaa acagtcggaa
    24181 gctggtatgc acgctggagt gaccgggtgg cagagcatga cctggaaacc ctgttctggc
    24241 agtggggcga gcgttttccg tcactggccg gaatggaacg ctggcagtgg caggatatgc
    24301 cattctggca ggtcatcgca gaggctggta tggcggcaag ggtggtcggt catgctgttc
    24361 gtgagatgga gcggtggatg gtgccgaaca aactccggga ggcagcgtga tgcggcaaca
    24421 atcacacgga tttcccgtga acggtctgaa tgagcggatt attttcaggg aaagtgagtg
    24481 tggtcagcgt gcaggtatat gggctatgat gtgcccggcg cttgaggctt tctgcctcat
    24541 gacgtgaagg tggtttgttg ccgtgttgtg tggcagaaag aagatagccc cgtagtaagt
    24601 taattttcat taaccaccac gaggcatccc tatgtctagt ccacatcagg atagcctctt
    24661 accgcgcttt gcgcaaggag aagaaggcca tgaaactacc acgaagttcc cttgtctggt
    24721 gtgtgttgat cgtgtgtctc acactgttga tattcactta tctgacacga aaatcgctgt
    24781 gcgagattcg ttacagagac ggacacaggg aggtggcggc tttcatggct tacgaatccg
    24841 gtaagtagca acctggaggc gggcgcaggc ccgccttttc aggactgatg ctggtctgac
    24901 tactgaagcg cctttataaa ggggctgctg gttcgccggt agcccctttc tccttgctga
    24961 tgttgtacgg gcatgaacaa cctgacttca ggaaggtcgt ttcccttcag gaacggggat
    25021 gaacgcgcgc ctgcggcgcc cgttcttttc ccccgccttc tctggttatg gcctgtcaga
    25081 aatcacatca ccttccctgt gattattctc tttttcttcc tgctctgatt ctgactactg
    25141 cagtgttgtc ctgtctgccg ggcgtacctt cggctcccgg ctgcctggcg gcatccggtc
    25201 gtcaggcccg actccgacag gcagctgctg gcgcacctgc cagtctccgc cgaacccgct
    25261 ggcgcggttt cgggctgttg ctacggtccg atgcgtgaaa acccctggct tgcagcgacc
    25321 gttccggtcg cgccgcctct gtcgcgccgt gacctgcgct cccggcatcc cggcaaaagg
    25381 cgccgggatg taaggcgcaa cgccgtttcg caaaccgcgc ttcacgtcgt tgcggcgggt
    25441 ccctgcccgt tgttgtgtcc ggtgccattc accagtttaa gcccctgtcg ccgggggcat
    25501 agacagccac aaccgtctcc gccagtccag gggtgaaatg cacatcccgc aaaacttttt
    25561 gcccagaagc aggcaaaaac ttttgcggtc tgcccccgga cagtcgtttc cggccgtggc
    25621 agtgatgccc catgcggcga aggttctcaa acaggtgatg gtgaataccg gagggaacaa
    25681 aaggcaggtc cccgcaaaac gtcaaaaccg cggctcccga aactcaacag atgatggggg
    25741 ctgaaaacca gagagaggag aaagcaggat gagtacccga aatatccacg ttaacaccgc
    25801 gtcgtacacg cttcttgttg ccgggaagaa aaaaaacacc ggggaagagt gggacgtcct
    25861 ggaattcagc agcctgactg agctgaaaaa atatcgcaaa agccacccgg aaaagatggc
    25921 cttcagttat agctacgcgc tcagtcaggg tgtggataag cagttccgcc atatcaacat
    25981 tgcggaagcc gatcacttca aacagttcct gcgtcagatt aagcgtgccg gcctcgatat
    26041 ccgggcgatc tgctgaccgg atgtgatgaa tatccctcct gattgttgca atcttgttaa
    26101 tggagatcgg ggggatgata ttaagcggaa aaatttttta ttaaatttat tctttcataa
    26161 aggagtagct gttatgcgat tagcttcccg ttttggtcgg tataattcca tccgccgtga
    26221 acgtccttta acggatgatg aattaatgca gttcgtgcct tcggtatttt ccggtgataa
    26281 acatgagtcc cggagtgaac gttatacgta tattccaaca atcaatatca tcaataagtt
    26341 acgtgatgaa ggtttccagc cattctttgc ctgtcagagt cggattcgtg atttgggacg
    26401 tcgcgaatac agtaaacata tgttacgtct tcgcagggaa gggcatatta acggacagga
    26461 agttcctgaa attatcctgc ttaattcaca tgatggttca tccagttatc agatgatccc
    26521 cggaattttt cgttttgtct gcacaaatgg cctggtgtgc ggaaataatt ttggcgaaat
    26581 ccgcgttcca cataaaggtg atattgtcgg gcaggttatc gagggagcgt atgaagtgct
    26641 cggtgtcttt gataaggtca ctgataatat ggaggcgatg aaagaaattc atcttaacag
    26701 tgacgagcaa catttatttg gcagagctgc actgatggtc aggtatgaag atgaaaataa
    26761 aacgccagtg acacctgaac agataattac tccccgtcgt cgggaagaca aacagaacga
    26821 tctctggaca acctggcagc gggttcagga gaatatgata aaaggtggat tatcggggcg
    26881 aagtgcctcc gggaaaaata ccaggacaag agccattaca ggtattgatg gtgatataag
    26941 aatcaacaag gcgttatggg tgattgccga acagttcaga aagtggaagt catgataata
    27001 taagtaaagc cccgaaaaaa ttttcggggc tttacttata ttatcatttt tcggcattgc
    27061 tgtgtcgtct gatatacctc aatttcatca accggctttc cggttgtctg taaatattgt
    27121 gcccgcgaaa aatggtctgg caggaggctg cacagttacc gggtatatat aagatgggtt
    27181 cccgcttcgc ggggcttcgg ccagtcagta ttgtcactca tatgatattt ttgtgtgtgg
    27241 ccttccatgc cgcttttgcg gcataaccgg tatctgacaa tgtctgtaag attaattgtt
    27301 ctgcacgctg ttaatttccg gaagtgattt cttcgtggcc ggaagccgga tacctttact
    27361 gctttttatc ccagtataaa tccggtaaac atctgatgcg taggcaagac gtctctggtt
    27421 ctggcgttcg gttttcctga atccggcatt gtatgcacca acggcctccc aggtgacgcc
    27481 ccatttttta aatgctattg ccagataata agcaccggta taaatgttca tgcagggatc
    27541 tgttgtcaga tgttctggct taattccgta gcgggccagt tcgttaaaat gctgggaatc
    27601 tacctgcatc agtccgctgc catatcccgt taccggatta ataccgatgg cattaacccg
    27661 gtaacgggat tcttgccatg atattgctct cagtaaatca ggatctattt tgtaatcccg
    27721 gcctgcaaga tcaaagcaat cagtggcctg gcagatctca tttataaaca tcaggcagat
    27781 ggttaacatc cattttttca tttttccacc tctggtgact ttatccgtaa ataatttaac
    27841 ccactccaca aaaaggctca acaggttggt ggttctcacc accaaaagca ccacacccca
    27901 cgcaaaaaca agtttttgct gatttttctt tataaataga gagttatgaa aaattagttt
    27961 ctcttactct ctttatgata tttaaaaaag cggtgtcggc gcggctacaa caacgcgccg
    28021 acaccgcttt gtaggggtgg tactgactat ttttataaaa aacattattt tatattaggg
    28081 gtgctgctag cggcgcggtg tgttttttta taggataccg ctaggggcgc tgctagcggt
    28141 gcgtccctgt ttgcattatg aattttagtg tttcgaaatt aactttattt tatgttcaaa
    28201 aaaggtaatc tctaatggct aaggtgaacc tgtatatcag caatgatgcc tatgaaaaaa
    28261 taaatgcgat tattgagaag cgtcgacagg aaggggcaag ggaaaaagat gtcagttttt
    28321 cagcaacagc ttcaatgctt cttgaactgg ggcttcgtgt acatgaggct cagatggagc
    28381 gtaaagagtc tgcatttaat cagactgagt ttaataaatt gcttcttgaa tgcgttgtaa
    28441 aaacacaatc atcagtagcg aaaattttgg gtattgagtc tctcagtcct catgtctccg
    28501 gaaatccaaa gtttgaatat gccaatatgg ttgaagatat cagggagaag gtatcatctg
    28561 agatggaacg attttttcca aaaaatgatg atgaataaaa gaaatttgac ttcgttcaaa
    28621 tatcagagtt tttatgattt aaaaaggtga cagtacgaaa gataattagt atattaatta
    28681 cgtggttaat gccacgttaa aatttgaatt tgaaaatcgc cgatgcaggg agttctctcc
    28741 tccctgcatc gactgtccat agaatccttt gtgaggaggt tcctatgtat ccgatggatc
    28801 gtattcaaca aaaacatgct cgtcaaatag atctgctgga aaatctgacg gcagttattc
    28861 aggattatcc aaatccagcc tgtatcaggg acgaaactgg aaaatttatt ttttgcaata
    28921 cgctgtttca tgagtcattt cttacacaag atcaaagtgc tgaaaaatgg cttctgtcgc
    28981 agagagattt ttgtgaattg atctctgtca cagagatgga agcatacagg aatgagcata
    29041 cgcatcttaa tcttgtagag gatgttttta ttcagaacag attctggaca atatctgtcc
    29101 agtcatttct taatggacac agaaatatta ttctgtggca attttatgat gctgctcatg
    29161 ttcgtcataa agacagttat aatcaaaaaa cgattgtcag tgatgatatc agaaatataa
    29221 tcagaagaat gagtgatgat tcttctgtat catcatatgt aaatgatgtc ttttacttat
    29281 atagcaccgg aatcagtcat aatgctatag caagaatatt aaatatatcc atctccacat
    29341 caaagaaaca cgcatctctg atatgcgact acttctctgt ttctaataaa gatgagttaa
    29401 ttatcttact ctacaataaa aagtttattt attatttata cgagaaggct atgtgtatca
    29461 taaatacgcg ttaataaggt gttgataaaa tatagacttt ccgtctattt accttttctg
    29521 attattctgt aaacataagt ggtaaccaga agataaacag cgggaggtgt tattgaaaag
    29581 atttggtaca cgttctgcaa caggtaagat ggtaaaacta aaattacctg tagatgtgga
    29641 aagtctatta attgaggcaa gtaacagaag cggaagaagt cgatcgtttg aggcagtaat
    29701 aagacttaaa gatcatcttc accgctatcc aaagtttaac agggcaggga atatctatgg
    29761 taagtcgctg gttaagtatc tgacaatgcg tctggatgat gaaactaacc agctacttat
    29821 tgcagccaaa aatcgtagtg gatggtgtaa aacagatgag gctgcagaca gagttattga
    29881 tcatttgatc aagtttcctg atttttataa ctcggagata ttcagggagg cagataaaga
    29941 ggaagatata acatttaata cactctagtt ttattcattt atccgaaatt gaggtaactt
    30001 atgaatgctg ttttaagtgt tcagggtgct tctgcgcccg tcaaaaagaa gtcgtttttt
    30061 tctaaattca ctcgtctgaa tatgcttcgc ctggctcgcg cagtgatccc ggctgctgtt
    30121 ctgatgatgt tcttcccgca gctggcgatg gccgccggca gcagtggtca ggacctgatg
    30181 gcaagcggta acaccacggt taaggcgacc ttcggtaagg actccagtgt tgttaaatgg
    30241 gttgttctgg ctgaagttct ggtcggtgct gtcatgtaca tgatgaccaa aaacgtcaag
    30301 ttcctggccg gttttgccat catctctgta tttattgctg tgggtatggc cgtcgttggc
    30361 ctctgacagg aaataaaacg atgtcgggag acgagaataa acttaagaaa tatcgtttcc
    30421 cggaaacact gaccaaccag agccgctggt ttggcctgcc actggatgaa ctgatccccg
    30481 cagcaatctg tattggctgg ggtatcacaa catcgaaata tctgttcggt attggtgcag
    30541 cggttctggt ttatttcggg attaaaaaac tgaaaaaagg gcggggcagt tcctggttac
    30601 gtgacctgat ttactggtat atgccaacag ccctgctgcg cggtattttt cataatgttc
    30661 ccgattcgtg tttccggcag tggattaaat agaactgata ccaggattgt tatatggaac
    30721 acggtgcccg tttaagtacc agtcgtgtaa tggccatcgc ctttatattt atgtcagtgc
    30781 ttattgttct cagcctctct gttaacgtca ttcagggggt gaataactac cgtcttcaga
    30841 atgagcaacg cactgccgtg acgccaatgg catttaatgc cccctttgcc gtgtcacaga
    30901 acagtgccga cgcctcttat ttacagcaga tggcgctgtc atttattgcc ctccgtctga
    30961 atgtttcatc agaaaccgtc gatgcctcac atcaggcgct tctgcaatat atccgcccgg
    31021 gcgcacagaa ccagatgaaa gttattctgg ctgaagaagc gaagcgtatt aaaaacgata
    31081 acgtgaactc agcctttttc cagaccagtg ttcgtgtctg gcctcagtat ggccgtgtgg
    31141 aaattcgagg tgtgcttaaa acctggattg gtgattcaaa acctttcact gatatcaaac
    31201 attacatcct tattctgaag cgggaaaacg gggtgacctg gctggataat ttcggggaaa
    31261 cagacgatga gaaaaaataa tacggcaata atattcggca gcctgttttt ttcctgcagc
    31321 gtgatggccg caaacggtac gctggccccc accgtggtgc caatggtgaa cggtggtcag
    31381 gccagtattg ccatcagcaa taccagcccg aatctgttta ccgttcccgg tgaccggatt
    31441 atcgccgtga acagtctgga tggtgccctg accaataatg agcagaccgc ctccggcggt
    31501 gtggtggttg ccaccgtcaa caaaaagccc tttacgttca ttctggaaac agaacgtggt
    31561 ctgaatcttt ccattcaggc cgttccccgt gaaggcgcgg ggcgtaccat tcagctggtc
    31621 agtgacctgc gcggaaccgg agaagaagcc ggtgcgtggg aaacgtccac gccttacgaa
    31681 tccctgcttg tgaccatcag ccaggccgtc cgtggcggaa aattacccgc aggctggtat
    31741 caggtcccag tgacaaagga aaccctgcag gccccggcgg ggctgtcttc agtggcagat
    31801 gccgtatgga cggggaatca cctgaagatg gtccgctttg ccgtggaaaa taaaacgctg
    31861 tctgccctga atatccggga aagtgacttc tggcagccgg gaacccgtgc cgtgatgttc
    31921 agccagcctg ccagccagtt actggcaggt gcgcgcatgg atgtgtatgt catccgtgac
    31981 ggggagggca actgatggcc agtatcaata ccattgtgaa acgcaagcag tacctgtggc
    32041 tggggattgt ggttgtcggt acagcctccg cgattggtgg ggcactgtat ctgtctgatg
    32101 tggacatgtc cggtaacggt gaaaccgtgg ctgaacagga gcctgtgccg gatatgaccg
    32161 gtgtggtgga tacgaccttt gatgacaagg tgcgtcagca tgccaccacc gagatgcagg
    32221 tgacggcagc gcagatgcag aagcagtatg aggaaatccg tcgtgagctg gatgttctga
    32281 acaaacagcg cggtgatgac cagcgtcgta ttgaaaagtt gggacaggac aatgccgccc
    32341 tggcagagca ggtaaaagcc ctgggtgcta atcccgtcac ggcgaccggt gagcctgtac
    32401 cgcagatgcc tgcctcaccg cccggcccgg aaggcgaacc acagccagga aacacccccg
    32461 tatccttccc gccgcagggc agcgttgctg ttccaccgcc gacggcgttt tatcccggga
    32521 atggtgtcac gccaccacca caggtgacgt accagtctgt gccggtgcct aaccggatac
    32581 agcgtaaggt gtttacccgt aatgagggaa aacagggacc atcactgccg tacattccgt
    32641 caggaagttt tgcgaaagcc atgctgattg aaggggcgga tgccaatgcc tctgtcaccg
    32701 gtaatgaatc cacggtgccg atgcagctgc gtatcaccgg cctggtggaa atgccgaaca
    32761 gcaagacgta tgacgcaacg ggatgttttg tgggtctgga agcctggggg gatgtgtcca
    32821 gtgagcgtgc cattgtacgc acccgcaata tcagttgcct gaaggacggc aaaactattg
    32881 atatgccgat taaggggcat gtcagcttcc ggggtaaaaa cggtatcaag ggcgaagtgg
    32941 tgatgcgtaa cggcaaaatc ctcggctggg catggggcgc gggatttgtt gacggtatcg
    33001 gtcagggaat ggagcgcgcc tcccagccgg ctgtcgggct gggtgccaca gccgcttacg
    33061 gggctggtga tgtcctgaaa atgggtatcg gtggcggcgc atcgaaagcc gcacagacgc
    33121 tcagtgacta ctacatcaaa cgtgccgaac agtatcaccc ggtgataccg attggtgcgg
    33181 gcaacgaagt gaccgtggtg ttccaggacg gcttccagct gaaaaccgtg gaagagatgg
    33241 cgctggaacg cacgcagagc agagcggaag aagacaatcc ggaaagtccg gttcctgttc
    33301 cgccatcggc tgaaagtcat cttaacggct ttaatactga ccagatgctg aagcagctgg
    33361 gcaacctgaa tccgcagcag tttatgtccg gcagccaggg agggggcaac gatggcaaat
    33421 aatatgtcgt cccgtcaggc gtgccatgcc gcccggtatg ttgtcgcccg ggttctgcga
    33481 ggactgttct ggtgtctgaa gtacaccgtc attctgccac tggccacaat ggccctgatg
    33541 gctctgtttg ttttatggaa ggacaacacc acgccgggga aattactggt taaggagatt
    33601 aacttcgtaa gacaaacagc acctgccgga cagttcccgg tcagtgaatg ctggttttct
    33661 tcctctgatt cttcaggcag atcagaaata caggatatct gccattaccg cgcggctgat
    33721 gctgcagatt atgtcaggga gactgaccgg tcactgatgc aactggtcac cgcattatgg
    33781 gcaacactgg cactgatgta tgtctcgctg gcagcgatca ccgggaaata tccggtgcga
    33841 ccaggaaaaa tgaaatgtat ccgggtggta accgcagatg aacatctgaa ggaagtttat
    33901 acggaagacg cttccctgcc gggaaaaatc aggaaatgcc ctgtttatct tcctgatgac
    33961 agaacaaaca gaaacaacgg agataaaaat gaacatgcgt aatattaatg ttattacagc
    34021 cctctctgtg ccgggtaaaa ccgtgtcaga tgattttatg catgctgttc tcagtaactg
    34081 cgccacaaga atcgtacttc ctgcaccgga gaaattcggt tctgagtcat tgccggacaa
    34141 ttttaatatg actgctgtcg gtgtgatgaa gaattcagaa atataaggaa cccttcgatg
    34201 aataagctgg tttctgatgg cagcgtcaaa aaaataaatt atccggtgct gtatgagtcc
    34261 ggaataacac ctccgttatg tgaagtcagt gcaccagaac ctgatgcggg tgggaaacgc
    34321 attgtggcat atgtttataa atcatcacgg agtacggttt ttgaaaatcc tgacattgta
    34381 aaaacctgta cggtcaggga tttgaagaag gattttgtga actgcgatga gaaaggtgag
    34441 ggacaatgaa acagatttct ttctttattc ctctgctggg gaccttatta ctttccggct
    34501 gtgccggaac cagtacggaa tttgagtgta acgccaccac atccgatacc tgtatgacga
    34561 tggagcaggc caatgagaag gccaaaaaac tggagcagtc ctcagaagca aagccggttg
    34621 cggcatcact gccgcgcctg gctgaaggga acttccggac aatgccggtg cagaccgtca
    34681 ccgcgaccac tccgtccggc agcagacctg cggtgacagc acatccggag cagaaactgc
    34741 tggcacctcg cccgctgttt accgctgccc gggaagtgaa aacggttgtt ccggtcagtt
    34801 cagttacgcc ggtaacacct cctcgtccgc taagaacggg tgagcagacg gcagcattat
    34861 ggatagcgcc ttatattgat aaccaggatg tttatcatca gccatccagc gtgttttttg
    34921 ttattaaacc gtctgcgtgg ggaaaaccac gtattaatta actggccctg aagttgtata
    34981 tcagccggca atgccggcgg gctttctgta ttcaaaatct gcctgtaaaa cgagtgccct
    35041 gtgcgtgaaa agggatgggc ggtagcgtgt cagaacatgt cgggaggaat attccgtgag
    35101 tgatgaagcc gatgaagcat attcagtgac agaacaactg accatgacag gaataaaccg
    35161 gatacgccag aaaataaatg ctcatggtat tcctgtttat ctctgtgaag catgcggaaa
    35221 tcctattccg gaagcccggc ggaaaatatt tcccggtgtg acgttgtgcg ttgaatgtca
    35281 ggcgtatcag gaaagacaga gaaaacatta tgcataagtc agtcgcagaa catagtgatt
    35341 taattccgga tgaacatgag tggatattca gaaaacagaa atctttgtat atgcgccggg
    35401 aaatggcgcg ttaattacag gtattccctt catggctacc gcatttctcg ctttattttt
    35461 caactaagga attcatgtga ataacccact tgaggccgtc actcaggcgg ttaactccct
    35521 cgtcacagca ctgaaactgc ctgacgaatc cgcaaaggcc aatgaagttc tgggcgaaat
    35581 gagcttcccg cagttcagcc gtctgctgcc gtaccgtgat tacaaccagg aatccggtct
    35641 gttcatgaat gacaccacga tgggctttat gctggaagcc atccccatca atggggcgaa
    35701 tgagtccatt gtggaggccc tcgatcacat gctgcgcacc aaactgccgc gcggtattcc
    35761 gttgtgtatc catctgatgt ccagtcagct ggttggtgac aggattgaat acgggctgcg
    35821 tgagttctcc tggtcaggtg aacaggctga acggtttaac gccattaccc gggcctatta
    35881 tatgaaagcg gcagcgacac agtttccgct gccggagggg atgaatctgc ccctgaccct
    35941 gcgccattac cgggtgttta tctcgtactg ttctccttcg aagaaaaaaa gccgggccga
    36001 cattctggaa atggaaaacc tggtgaaaat catccgggcg tcgttacagg gggccagtat
    36061 caccacacag acggtggatg cacaggcctt tatcgatatt gtcggggaga tgattaacca
    36121 taacccggac tccctgtacc cgaaaagacg tcagctggac ccgtattctg atctgaatta
    36181 tcagtgtgtg gaggacagtt ttgatctgaa agtccgggct gattacctga cgctgggcct
    36241 gcgtgagaac ggcaggaaca gcacggcccg catcctgaat ttccatctgg cccgtaaccc
    36301 ggaaatcgcc ttcctgtgga acgtggccga caactacagc aacctgctga acccggaact
    36361 gtccatctcc tgtccgttca tcctgacgct gactctggtg gtggaagacc aggtgaaaac
    36421 ccacagcgaa gccaacctga agtacatgga cctggagaaa aagtcgaaga cctcctatgc
    36481 caaatggttt ccgtccgtgg agaaagaggc gaaggagtgg ggggaactgc gtcagcggct
    36541 gggctccggt cagtcctccg tggtgtccta cttcctcaac atcacagcat tctgcaagga
    36601 caataatgaa acggcgctgg aagtggagca ggacatcctg aacagctttc gtaaaaacgg
    36661 ttttgagctg atttcaccgc gctttaacca catgcgcaat ttcctgacct gcctgccctt
    36721 tatggccggg aaagggctgt ttaaacagtt gaaagaggcc ggagtggttc agcgcgcaga
    36781 gagctttaat gttgccaacc tgatgccgtt agtggcggat aaccccctga caccggcagg
    36841 tctgctggca cccacctacc gtaaccagct ggcgtttatc gatattttct tccgggggat
    36901 gaataacacc aactacaaca tggcggtctg tggcacctcc ggggccggta aaaccgggct
    36961 gatacagcca cttatccgca gcgtgctgga ctccggaggc tttgccgtgg tgttcgacat
    37021 gggggatgga tacaagtccc tgtgtgagaa catgggcggg gtgtatctgg acggtgaaac
    37081 cctgcgtttt aacccgtttg cgaacatcac cgatattgac cagtcagcgg agcgtgtccg
    37141 tgaccagttg tcagtgatgg ccagccccaa cggtaacctg gatgaagtgc atgaaggtct
    37201 gctgttgcag gcggtcagag cctcctggct ggccaaagag aacagagcac gtattgatga
    37261 cgtggtggat ttcctgaaaa acgccagtga cagcgagcag tatgccgagt caccgactat
    37321 ccgcagccgt ctggacgaaa tgattgtgct gcttgaccag tacactgcca acggcactta
    37381 cggccagtat tttaactctg atgagccgtc cctgcgggat gacgcaaaaa tggtggtgct
    37441 ggagctgggc ggactggaag accgtccgtc actgctggtt gcggtgatgt tctccctgat
    37501 tatctacatc gagaacagga tgtaccgcac gccgcgtaac ctcaagaaac tgaacgttat
    37561 tgatgaaggc tggcgtctgc tggacttcaa aaatcacaag gtcggtgaat ttattgagaa
    37621 aggctaccgt acggcccgcc gtcataccgg tgcctatatc accatcacac agaacatcgt
    37681 cgactttgac tctgataagg cctccagtgc tgcccgcgcg gcatggggta actcctccta
    37741 caaaattatc ctcaaacaga gtgcgaagga gttcgcgaaa tacaaccaac tgtatccgga
    37801 ccagttcctg ccactgcagc gcgacatgat tggtaagttt ggtgcggcca aagaccagtg
    37861 gttcagttcc ttcctgctgc aggtggaaaa ccattcctcc tggcaccgtc tgtttgtgga
    37921 cccgttaagc cgcgccatgt acagctctga cggcccggat tttgagtttg tgcagcagaa
    37981 gcgtaaagag gggctgagta ttcatgaggc agtgtggcag ctggcgtgga agaagtcagg
    38041 gccggaaatg gcttcgctgg aagcctggct ggaagaacat gagaaataca ggagtgtggc
    38101 atgagttcaa cgcagaaacc cgccgacgtc atggcagaac gacgcagcca ctggtggtgg
    38161 acggtgccgg gatgcctggc aatggtgtta ctgaacgcag ccgtcagtta cggcattgtc
    38221 agactgaacg caccggtgac tgtcgccttc aacatgaaac agaccgtgga tgcgtttttt
    38281 gacagagcca gtcagaaaca actgtcagaa gcgcagtcaa aagccctttc agcgcgtttt
    38341 aacacggcac tggaagccag cctgcaggcg tggcagcaga aacaccacgc ggtcattctg
    38401 gtgtcgcctg ctgtggtaca gggggcaccg gatatcaccc gggaaatcca gcaggatatt
    38461 gcccggcgaa tgagggcgga accatgagat gccgggggct gattgccctg ctgatatggg
    38521 ggcagagtgt ggccgccgcc gatcttggta cctggggcga tctgtggccg gtaaaggagc
    38581 cggacatgct gacggtgatc atgcagcgcc tgacggcact ggagcagtcc ggtgagatgg
    38641 gccggaaaat ggatgccttt aaggagcggg tgatccgcaa cagtctgcgg ccccctgccg
    38701 tgcccggtat cggacgcacg gagaaatacg gcagccggtt gtttgacccg tccgtcagac
    38761 tggctgcgga tatccgggat aacgaagggc gggtgtttgc ccgtcagggt gaagtgatga
    38821 atccgctgca gtatgttcct tttaaccaga cgctgtattt catcaatggc gatgatccgg
    38881 cgcaggtggc ctggatgaaa cgccagacgc cgcccacact ggagagcaaa attatcctcg
    38941 tgcagggcag tatcccggag atgcagaagt ctctggacag ccgtgtttac tttgaccaga
    39001 acggtgtgct ctgccagcgc ctcggcattg atcaggtccc ggcacgggtg agcgccgttc
    39061 ccggcgatcg cttcctgaag gtggaattta ttccggcaga ggagggcaga aaatgaagcg
    39121 aaggctgtgg ctgctgatgt tattcctttt cgccggtcat gtccctgcgg cgtctgcgga
    39181 ttctgcctgt gaggggcgtt ttgtaaaccc gatcacagat atctgctgga gctgtatttt
    39241 cccgctctcg ctgggcagta tcaaagtcag tcaggggaag gtccccgaca cggcgaaccc
    39301 gtcgatgccc attcagattt gtccggcact gccgccgctg ttcaggcgta tcgggctggc
    39361 cattggttac tgggagccga tggcgttgac ggacgtcacc cggtcaccgg gatgcatggt
    39421 gaacctgggc ttcagcctgc cggcttttgg taaaacggca cagggaacgg cgaaaaagga
    39481 tgagaagcag gtaaatgggg cgttctatca cgttcactgg tacaaatacc cgctgacgta
    39541 ctggctgaac atcatcacat cgctgggctg tctggaaggt ggtgacctgg atatcgctta
    39601 tctttctgaa atcgacccca cctggacgga cagcagcctg accaccattc tcaatccgga
    39661 agctgtcatc tttgccaatc cgatagcaca gggagcctgc gcagcagatg cgattgccag
    39721 cgcctttaat atgcctctcg atgttctgtt ctggtgtgcc ggttcgcagg gaagtatgta
    39781 cccgttcaat ggctgggtga gtaatgagtc cagtccgttg cagtcctccc tgctggtcag
    39841 tgaacgcatg gcgttcaagc tgcaccgtca gggcatgatt atggaaacca tcgggaaaaa
    39901 taacgccgtc tgtaatgaat atccatcccc aatcctgccc aaagaacgct ggcgttacca
    39961 gatggtgaat atgtacccgg acagcggaca gtgccacccg ttcgggcgca gtgtgacccg
    40021 ctgggaaacc gggaaaaatc cgcccaatac aaagaaaaac ttcggctacc tgatgtggcg
    40081 taaacgtaac tgtgtcttcc tgtgaggtga atgatgaagc tgagtatgaa atctctggca
    40141 gcactgctga tgatgctgaa cggggcggtt atggcgtcag aaaacgtgaa cactcctgaa
    40201 aaccgccagt tcctgaagca gcaggaaaat ttaagcagac aactgcgtga aaaacctgac
    40261 catcagctga aagcctgggc ggagaagcag gtgctggaaa ccccccttca gcgttcagat
    40321 aaccatttcc tggatgagct ggttcgtaaa cagcaggctt cgcaggacgg gaaaccccgg
    40381 cagggtgccc tgtattttgt gtcgttttcc attcccgaag aggggctgaa acgaatgctg
    40441 ggcgaaaccc ggcactacgg tatacccgcc acactgcggg gcatggtgaa caatgacctg
    40501 aagaccaccg ctgaagccgt gctgtccctg gtgaaagacg gcgcgactga tggtgttcag
    40561 atcgacccga cgctgttttc acagtacggc attcgcagtg taccggcact ggtggtgttc
    40621 tgcagtcagg gatacgacat catccgggga aacctgcggg tcggccaggc gctggagaaa
    40681 gtggccgcca cgggtgactg ccggcaggtg gctcatgatt tactggcagg gaaaggagat
    40741 tccgggaaat gaaacgtatt ttacctctga tactggctct ggttgccggc atggcacagg
    40801 ctgacagcaa cagtgattac cgggccggct ctgattttgc tcaccagatc aaagggcagg
    40861 gaagcagcag tattcagggc tttaagccac aggagagtat ccccggctat aacgcgaatc
    40921 cggacgagac aaaatattac ggtggcgtga ctgccggcgg ggatggcggc ctgaaaaatg
    40981 acggcaccac ggaatgggcg accggtgaaa ccggaaaaac catcacagag tcattcatga
    41041 acaagccgaa agacattctt tcaccggatg caccgtttat ccagaccggc agggatgtgg
    41101 tgaaccgggc tgacagcatt gtgggaaaca ccgggcagca gtgcagtgcg caggagatta
    41161 gccggagtga atacacgaat tacacctgtg agagggattt acaggtggag cagtactgca
    41221 cacgaactgc ccgtatggag ctgcagggga gtaccacatg ggaaacccgg acgctggagt
    41281 atgaaatgag tcagctacct gcacgtgaag tgaatggtca gtatgttgtc tccattacct
    41341 ctcccgttac cggtgaaatt gtcgatgcgc attacagctg gagtcgtact tacctgcaga
    41401 agagtgtacc tatgacaatt acagtactgg gaaccccact gagctggaat gccaaatact
    41461 cagcagatgc ctcatttaca ccagtacaga aaacactgac tgccggtgtt gcttttacgt
    41521 catctcaccc cgtccgggtc gggaatacaa aattcaaacg tcatacggca atgaagctgc
    41581 gtctggttgt cagggtaaaa aaagcctcgt acaccccgta tgttgtctgg tctgaaagct
    41641 gcccgttcag caaggagctg gggaaactga caaaaacaga atgtacggag gctggcggga
    41701 acaggacgct ggtgaaagac ggtcagtcat acagcatgta ccagagctgc tgggcatacc
    41761 gggacacgta tgtcacgcag tcagcagaca agggaacctg tcagacctac accgacaatc
    41821 ctgcctgtac cctggtgtca caccagtgtg ccttttactc cgaagaaggt gcctgtctgc
    41881 atgaatatgc cacgtactcc tgtgagtcaa aaacatccgg gaaagtgatg gtctgtgggg
    41941 gagacgtctt ctgtctcgat ggcgaatgcg ataaggctca gagcgggcag agtaatgatt
    42001 ttgccgaagc cgtttctcag ctggcggcac tggccgcagc aggtaaggat gttgcggcgc
    42061 tgaacggggt ggatgtccgt gctttcaccg gtcaggcgaa attttgtaag aaggctgcag
    42121 ccggatacag caactgctgt aaggacagcg gctggggaca ggatatcggg ctggccaaat
    42181 gcagcagtga tgaaaaggcc ctggctaaag caaaatcaaa caaactgacc gtcagcgtcg
    42241 gggagttctg ttcgaagaaa gtgctgggtg tctgtctgga gaaaaaacgc agctactgtc
    42301 agtttgattc gaagctggcg cagatagtcc agcagcaggg gcgcaacggt cagttgcgta
    42361 tcagttttgg tagtgcgaag catcctgact gtcgggggat tacggttgat gagctgcaga
    42421 aaattcagtt caacagactg gatttcacta acttctacga agacctgatg aataaccaga
    42481 aaatcccgga cagtggcgtt ctgacgcaga aagtgaaaga gcagattgct gaccagctga
    42541 aacaggcagg acagtaaggt atgggaaata accgggggaa atgatgaaag tcatattcac
    42601 gtcgaaccgt tttattgatt ttcttatccg gcttttgatt acagcgattg tcatttctct
    42661 ggtaattatc tggtcgtggg atacggtaaa agaaaccacg gcagacggga tgcttgccgc
    42721 tgctttcgtt atcctttact ccggtgtgct cctgtttatt ctgtattttt gtttttctgc
    42781 cctgactgac ctgcagaaac ctgatgaaag aaaaagtgat gaaaggaatg aagatgaata
    42841 aagcattact gccactgtta ctctgctgct ttatttttcc ggcgtcagga aaagatgcag
    42901 gctggcagtg gtataacgag aaaataaatc cgaaggaaaa agaaaataaa cctgtacctg
    42961 cagccccccg tcaggaaccg gatattatgc agaaactggc cgcactgcag acggcaacaa
    43021 agcgggcgct gtacgaagcc attctgtatc ccggcgtgga taattttgtg aaatatttcc
    43081 ggctgcaaaa ttactggact cagcaggccg ggcttttcac catgagcgcc agaaaggcca
    43141 tgctggcaca tcctgaactg gactataacc tgcagtacag ccattacaac ggcacggtac
    43201 ggaaccagct ggcagcagac caggcgcagc agcgacaggc cattgcgaaa ctggctgaac
    43261 actacggcat catgtttttt taccgggggc aggaccccat cgacgggcag ctggcgcagg
    43321 tcattaatgg cttccgggat acctatggtc tgagtgttat tcccgtttcc gtggatggcg
    43381 tgattaatcc gctgttgccg gattcccgga ctgaccaggg gcaggcgcag cgcctcggcg
    43441 tgaaatattt cccggccatg atgctggttg acccgaaaca gggtagtgtt cgtccgttat
    43501 catacggttt tatttcgcag gacgacctgg caaaacagtt cctgaatgtc tctgaggatt
    43561 ttaaaccgaa tttttaacca aaggatatat atgcatacag gggatttgtg tttttttaca
    43621 ggtgccagcc tgtttatcgt gggggttgtt ggttatttct ttacaggact aaataataaa
    43681 ggagtttatc tactgagctc gtttgtcttc tttgtagtaa atgtcataag tgtatgtatg
    43741 ctgccagata atttcttgtt tctttgtggt gcggttatga atcagtgtgc cgtaccggtt
    43801 gtttcaatgg cagtcagcac catgccgatt atcacgaagt ttgacagttt cagaaggatg
    43861 tttatttgta ttatgttgtc agccatatgg tctggagtga tgtggttttt tattatttca
    43921 ttagtgaaat gactggtgct aatttgtcat aaatgccaaa tccaatagtg aggttgatta
    43981 ccacagacca gaggataaac cagactgcta tccagtgact tctgaataaa tcacaaaaat
    44041 aaacatagat gattagaaat agccatatca caacagcgat aattgctata aataacagta
    44101 tcgtcacaaa taaatcagca aaggttttaa tggggagagt gtgcaataat gaatacacca
    44161 gtaaagcaaa agccgcatta cctgataatg actctcttat gatgtttctc actatttcca
    44221 gtttttcttt aaaagatcgc ttttccattt gtacctctga ctaatatcac acaaacgcga
    44281 atattacaga catgaatact ctcatgtaaa taataaccgg agtttaacat gataagtaaa
    44341 cgcagattct ctttaccccg gcttgatatt acgggaatgt gggtattttc cctgggcgtc
    44401 tggtttcata tcgtcgcccg tcttgttcac agcaaaccct ggatggcttt ttttctggcg
    44461 gagctgattg cggccatcct tgtgctgttc ggcgcatacc aggtgctgga tgcatggatt
    44521 gcccgtgtca gccgggaaga gcgtgaggca ctggaagcca ggcaacaggc catgatggca
    44581 gagcagcagg agggcggaca tgtctctcac taaattactg ccggttattc tgttgatgat
    44641 ggccacaggt gtgcaggcct ccacccggga tgaaattgaa cgactctggc atccgcaggg
    44701 tatggctgcg cagcctgcac aaccggcagc agacacgcca gccaggacag acaagacaga
    44761 aaagccggct ccccgctggt tccgcctcag caacggcagg caggttaacc tggccgactg
    44821 gaaggtggtg ctgtttatgc aggggcattg cccttactgt caccagtttg acccggtact
    44881 gaagcagctg gcacagcagt acggcttttc cgtttttccc tacactctgg atggtcaggg
    44941 ggatatggcc tttccggaag cattaccggt gccaccggac gtgatgcaga ccttcttccc
    45001 gaatatcccg gtggccacac cgaccacctt cctggtcaac gtcaacacgc ttgaggcatt
    45061 accgctttta cagggggcaa cggatgccgc cggttttatg gcgcggatgg ataccgttct
    45121 gcagatgtac ggagggaaaa aaggtgcgaa ataagcaggt ggtgttactc attgccggaa
    45181 tatccggcat cgcgacggga ataatcgtca gcctgaatat tccctttatc cgtcaggggc
    45241 ttttttatcc cgccagtcct gtagaaatag tcgtttcgct gtgtcttacc ttttctgttt
    45301 ctgttgtgtt ttttgtgggg gcaattgtgg gatggatttc ggtgtctgaa atatattaca
    45361 gccgcatgac cggtctgaat gaatcatcag taatatcaga ggaaacttat aatgacaaaa
    45421 aacaaaaaga atcaggaatt caaaatcaga aaaattagac ggaatattga gtatagtttc
    45481 agaggttctg acagatattt ttatttgttt attgttttcc ttgttgccgg aattgtttta
    45541 tgggctgtta tgcacgttat tttcgatgtc tgtattgatt cgtggatggc cgacccgaaa
    45601 ttacttaatt tccagtatat gtggaatgtt ctgatgaaag tcattccgtt tacgttatgg
    45661 gcgctggcag caaggtttct tgttacattt tttctgtccc caatgtgcga attaatattc
    45721 ggaaatatca tgatattcct gctgaaacgc cgtatgcgcc gggagaacac attaagggag
    45781 ggcaagaatg atgccacgca ttaaacctct tctggttctt tgtgctgctt tactgacggt
    45841 cacacccgca gcgtcagcgg atgtgaacag cgacatgaat cagttcttta acaagctggg
    45901 cttcgcctcc aataccaccc agccgggcgt ctggcagggg caggccgccg gctatgctta
    45961 cggtggctcc ctgtatgccc gtactcaggt taaaaatgtt catctgattt ccatgacgct
    46021 gccggatatc aatgccggat gtggcggcat cgacgcctat ctcggctcgt tcagctttat
    46081 taatagcgag cagttgcagc gttttgttaa gcagattatg agcaatgctg ccggttactt
    46141 ctttgacctt gccctgcaga caacggtgcc ggaaatcaaa accgcaaaag acttcctgca
    46201 gaaaatggca agcgacatta acagtatgaa cctcagttcc tgccaggcgg cacaggggat
    46261 tatcggcggg cttttccccc ggacgcaggt gtcccagcag aaagtctgtc aggacattgc
    46321 cggtgagagc aatatttttg ctgactgggc tgcttcccgg cagggatgta ccgttggcgg
    46381 gaaatctgac agcgtcaggg ataaagccag cgacaaggat aaggagcggg tgaccaaaaa
    46441 catcaacatc atgtggaatg cgctttccaa aaacagaatg tttgacggca acaaagagct
    46501 gaaagagttt gtgatgacgc tgaccggctc actggtgttt ggtcccaacg gcgaaatcac
    46561 accgctatcg gccagaacca ctgaccgctc aattatccgg gccatgatgg aaggcggtac
    46621 agcaaaaatt tatcactgca acgattctga caaatgcctg aaagtggtgg cagacacacc
    46681 ggtgaccatc agccgggata atgcactgaa gtctcagatt actaaacttc tggccagcat
    46741 tcagaacaag gctgtcagtg acacgcctct ggatgacaag gaaaaaggct ttatttccag
    46801 taccaccatc cccgtcttca aatacctggt tgacccgcag atgctcggtg tttccaacag
    46861 tatgatttac cagctgacgg actatatcgg ttacgacatc ctgctgcagt acattcagga
    46921 gctgatacag caggcccggg cgatggtggc cacgggaaat tatgacgaag cagttatcga
    46981 acatattaac gacaatatga atgatgccac ccggcagatt gcggcgtttc agtcacaggt
    47041 acaggtgcag caggatgcgc tgctggtcgt cgatcgtcag atgagctaca tgcgtcagca
    47101 gctttccgcc cgcatgctca gtcgttacca gaacaactat cacttcggag ggagcacgct
    47161 gtgaatgaag tttatgtgat tgccggtggt gaatggttgc ggaataacct gaacgccatt
    47221 gccgccttta tgggaaccag gacgtgggat tccattgaaa aaattgctct caccctgtct
    47281 gttgttgcgg tggcctttat gtgggtacag cgccataacg tgatggattt gctgggctgg
    47341 gcggcggtgt ttgtacttat cagcctgctg gttaatatcc gtacgtcggt gcagattatt
    47401 gataacagtg acctggtcaa agtccatcgg gtggataatg tgccggtcgg actggcgatg
    47461 ccactttcac tgacgacccg tatcgggcat gcaatggtgg ccagttacga gatgatctac
    47521 acgcaaccgg acagtttcac ctacagcaaa acggggatgc tgtttggcgc agaactggta
    47581 tcaaaaagca ccgacttttt gtcccgcaat ccggaaatcg ccaatctttt tcaggattat
    47641 gtgcagaact gtgtgatggg ggatatttac ctgaaccaca aatacacgct ggaggagctg
    47701 atggcctcca atgatcccta cacgctgatt ttttcccgcc ccagtccgct gcggggcgtt
    47761 tatgacagca ataataattt cgtgacctgt aaggacgcgt cggtttcgct gaaagacaag
    47821 ctgaatctgg acacacagag tggcggaaaa acctggcatt attatgccca gcagttattt
    47881 ggtggtcgcc ctgatccgaa cctgttgttc agtacgctga ttggcgacag ttaccgttac
    47941 ttctatgact caagtaaatc agccagccag atcatccgcc agaatgtcac cattaatgcg
    48001 ctgaaggagg ggatcaccag ttatgcagca cgtaatggtg actcagccag cctggtgaat
    48061 ctggccacca cgtcatcgat ggagaagcaa cgtctggcac atgtctccat cggtcatgtg
    48121 gcgatgcgga cactgcccat gacgcagacc atcctgacgg ggatcgccat cggtattttc
    48181 ccgctcctgg tactggcggc tgtcttcaac aaactgacgc tgtctgtcct gaaaggctat
    48241 gtgtttgccc tgatgtggtt gcagtcatgg ccaatgttgt atgccattct gaacagcgcc
    48301 atgacatttt atgcgaagca gaatggtgca ccggtggtgc tctcggaaat ttcacagata
    48361 cagctgaaat actccgatct ggcttccact gccgggtatc tttccatgat gatcccgcca
    48421 ttatcctgga tgatggtcag gggactcggg gccggatttt ccagtgtgta cagccatttc
    48481 gcttcctctg ctatcagccc gaccgccagt gcggcaggca gtgtggttga cggtaattac
    48541 tcctacggca acatgcagac ggaaaacgtg aacggcttca gctggagcac caacagcacc
    48601 acgtcgtttg gtcagatgat gtaccagacc ggcagtggtg caaccaccac acagacccgt
    48661 gacggtaata tggtgatgga tgcaagcgga gcgatgtccc ggttaccggt tggtatcaat
    48721 gcaacgcgtc agattgcagc ggcacaacag gaaatggccc gggaggcatc gaacagagca
    48781 gaaagcgccc tgcatgggtt cagcagcagt attgccagtg cctggaactc gctcagtcag
    48841 tttggttcta accgggggag cagtgattct gtcacaggtg gtgctgacag cacgatgagc
    48901 gcacaggatt ccatgatggc cagccgtatg cgcagtgcag tggaaagcta tgcgaaggcg
    48961 cataatatca gtaatgagca ggcgactcag gaactggcat caacaagtac caggctatct
    49021 ggtggaatgt atgctgatgc tcatgctgaa tggggggtta aacctaaaat tcttggtgtt
    49081 ggtggtgggg taggcatcag aggtggattt aaggggagct tggatgcaac ggatgatgac
    49141 tcacattcag caagtagtgg cagcagggct acccatgatg ctcgccatga tatcgatgcc
    49201 agagctacac aagactttaa agaggccagc gattacttta ccagtcgcaa agtcagtgaa
    49261 tccggcagcc atactgacaa taatgctgat tcccgtgtgg accagctgtc tgcagccctg
    49321 aattcagcga aacagagtta cgatcagtac acgacgaata tgacccgcag ccatgaatat
    49381 gctgaaatgg catcccgtac tgaaagcatg agtgggcaga tgagtgaaga tctgtcgcaa
    49441 cagtttgcac agtatgtgat gaaacacgca ccgcaggatg ccgaagctat tctgacaaac
    49501 accagttcac cggagattgc agaacgccgt cgggcgatgg catggtcttt tgttcaggaa
    49561 caggtgcagc ctggtgttga taatgcctgg cgtgaatccc gtggggatat tggtaaagga
    49621 atggagagcg taccttcggg tggtggcagc caggatatta ttgctgacca tcaggggcat
    49681 caggccatta ttgatcaaag aacgcaggac agtaatatcc gtaatgatgt aaaacatcag
    49741 gttgataata tggtcacaga atataaaggg aatatcggag atactcagaa tagtattcat
    49801 ggcgaagaaa atattgtaga cagacaatat tcagagttaa aaaataatca caaacaggaa
    49861 gaaattcaac aaaacaacag atataatgaa gaaaataaac gacagaaatt aataccaaca
    49921 ccgtctgaag atgcgttaaa acagatggtg gatgataaga aagaacgatt gaaggggcca
    49981 ttatgatcac tcactatgat ataaaaatgg agatgcaaaa actaaaggag gtactctctg
    50041 tagagggtgt taatatccca tcattattac aagtcataaa gccgggaact tatgtgtttt
    50101 tatgggtttt attatggcca acttttctgc gtttagtatc ggttaaaagt gatgtcaggg
    50161 atgttggctt tgatatatgt gctagtggaa tgatggggtt cctgcttttt gtggctatta
    50221 caaatggaat gatgttatac cttgcgattc ctgatagttt cagaaaggat tcaaaaataa
    50281 taaattttat gtattctaag agtaagacat atattttgtt gtttttgatt gttttttcta
    50341 tggtttcgtt tatgcattct atcttatatg tttttgcact aatgattaca ttcatattat
    50401 ttttcttggt gtataccata gatataaatc gttataatct ctcagcaata gtctcagtaa
    50461 taggactgtt caaaaaagag tctgttagtt aaaaggatat tttggatgaa aacaaaaaaa
    50521 ttgatgatgg ttgcactggt cagttccact ctggcccttt cagggtgtgg tgcgatgagc
    50581 acagcaatca agaagcgtaa ccttgaggtg aagactcaga tgagtgagac catctggctt
    50641 gaacccgcca gcgaacgcac ggtatttctg cagatcaaaa acacgtctga taaagacatg
    50701 agtgggctgc agggcaaaat tgctgatgct gtgaaagcaa aagggtatca ggtggtgact
    50761 tctccggata aagcctacta ctggattcag gcgaatgtgc tgaaggccga taagatggat
    50821 ctgcgggagt ctcagggatg gctgaaccgt ggttatgaag gcgcagcagt tggtgcagcg
    50881 ttaggtgccg gtatcaccgg atataattcc agttctgccg gtgccacact cggtgtgggc
    50941 cttgctgccg gtctggtggg tatggctgca gatgcgatgg tggaagatgt gaactatacc
    51001 atgatcacgg atgtgcagat tgcagagcgt actaaggcaa cggtgacaac ggataatgtt
    51061 gccgccctgc gtcagggcac atcaggtgcg aaaattcaga ccagtactga aacaggtaac
    51121 cagcataaat accagacccg tgtggtctca aatgcgaaca aggttaacct gaaatttgaa
    51181 gaggcgaagc ctgttctcga agaccagctg gccaaatcaa tcgcaaatat tctctgatta
    51241 tcttccggag gctggtctga ccggcctcct gactgacgcc tcgctttgct cgttgtccaa
    51301 ccccggaaag aaataaaata aattttattt ctccccggcg tttccgaaat aaatatgaaa
    51361 acactgagcg gttgtgcaaa ttctttgtgc gaccgtgaag tgttgccggc gaagccggaa
    51421 tttaacggtt attaatcttt tcatcattaa taatcagtcc gactgacttt tttcttcgga
    51481 atatcatcat gagttttaac gcaaaggata tgacccaggg cggtcagatt gcgtccatgc
    51541 gtatccgcat gttcagccag atcgccaata tcatgcttta ctgcctgttt atttttttct
    51601 ggatactcgt tggtctggtt ttatgggtaa aaataagctg gcagacgttt gtgaacggct
    51661 gtatttactg gtggtgtacc acgctggaag gcatgcggga tttaatcaag tcccagccgg
    51721 tatatgagat ccagtattac ggcaaaacct tccggatgaa cgctgctcag gtactgcatg
    51781 ataaatatat gatttggtgc ggagagcagc tatggtccgc attcgttctg gccacagttg
    51841 tggcactggt tatttgcctg attaccttct ttgttgtctc ctggattctg gggcgtcagg
    51901 gtaaacaaca gagcgaaaat gaagtcacag gtggtcgtca gctgacagac aatccgaaag
    51961 acgttgcccg gatgctgaaa aaagacgaca aggactccga tatccggatt ggcgacctgc
    52021 cgattatccg ggattctgaa atccagaact tctgtctgca cggcacggtc ggggccggta
    52081 agtcggaagt tatccgtcgt ctggccaact acgcccgtaa gcgcggtgat atggtggtga
    52141 tttatgaccg ttcaggggaa tttgttaaaa gttactatga tccctccatc gataaaatcc
    52201 tgaatccgct ggatgcccgc tgtgccgcat gggatttatg gaaggagtgt ctgacacagc
    52261 cggattttga taatacggca aataccctga tcccgatggg cacaaaagag gacccgttct
    52321 ggcagggttc aggacgtacc atttttgcgg aagcggcgta cctgatgcgt aatgacccca
    52381 accgcagcta cagcaaactg gtggacactc tgctttccat caaaatcgaa aaactgcgta
    52441 ccttcctgcg taattcaccg gcggccaacc tggtggaaga gaaaatcgag aaaacggcga
    52501 tttccatccg tgctgtgctg accaactacg tgaaagccat ccgttacctg caggggattg
    52561 agcataacgg tgagcccttc accatccgtg actggatgcg tggtgtccgg gaagatcaga
    52621 aaaacggctg gctgtttatc tcatcgaacg ccgacaccca tgcctccctg aagccggtga
    52681 tctccatgtg gctgtccatt gccattcgtg gtctgctggc aatgggagaa aaccgtaaac
    52741 gtcgtgtgtg gtttttctgt gacgagttac ccacgttaca caaactgcct gacctggtgg
    52801 agatcctgcc ggaagcccgt aagttcggtg gctgttatgt gtttggtatc cagtcctatg
    52861 cccagctgga agatatctac ggtgagaaag cggctgccac gttgtttgac gtcatgaaca
    52921 cccgtgcctt tttccgttct cccagccata agattgcaga gttcgctgcc ggtgagattg
    52981 gtgagaaaga gcacctgaaa gccagcgagc agtattccta cggtgctgat ccggtacgtg
    53041 acggggtatc gaccggtaag gatatggagc gccagacgct ggtcagttat tccgacattc
    53101 agtctctgcc ggatctgacc tgttatgtca ccctgcccgg accgtatccg gcagtaaaac
    53161 tctctctgaa atatcagaca cgaccgaagg tcgctccgga gtttattccg cgtgacatca
    53221 acccggaaat ggagaaccgc ctgagtgccg tacttgccgc aagggaagca gaaggtcgtc
    53281 agatagccag cctcttcgaa ccggatgtcc cggaggttgt ttccggagaa gacgtgactc
    53341 aggctgaaca gccgcaacag ccgcaacagc cgcaacagcc gcaacagccg caacagccgc
    53401 aacagccggt gtctcctgcc atcaacgata agaagtcaga ttcaggtgtg aatgttccgg
    53461 caggggggat cgagcaggag ctgaaaatga aaccggaaga agagatggaa cagcaactgc
    53521 cacccgggat cagtgaatcc ggtgaagtgg tggatatggc cgcttatgag gcatggcaac
    53581 aggaaaatca tccggacacc cagcagcaga tgcagcgtcg tgaagaggtg aacattaatg
    53641 tgcaccggga gcgcggggag gatgttgagc cgggagatga tttctgatga tgagtatcgc
    53701 acaggtcaga tcggccggaa gtgccggtaa ctattatacc gacaaggata attactatgt
    53761 actgggcagc atgggagaac gctgggccgg caggggggct gaacagctgg gactgcaggg
    53821 cagtgtcgat aaggatgttt ttacccgtct tctggaggga aggctgccgg acggagcgga
    53881 tctaagccgc atgcaggatg gcagtaataa gcatcgtccc ggctacgacc tgaccttctc
    53941 cgcccccaaa agtgtctcca tgatggccat gttaggtggc gataagcgcc tgattgatgc
    54001 acataaccag gccgtggact ttgctgttcg tcaggtggag gcgctggcct ccacacgggt
    54061 gatgacggac ggacagtcag aaacggtact gaccggtaat ctggtgatgg cactgtttaa
    54121 ccacgacacc agtcgcgatc aggaaccaca gttacacacg catgcggtgg tagctaatgt
    54181 cacgcagcat aacggtgagt ggaagacact gagcagtgac aaagtgggga aaacggggtt
    54241 cattgagaat gtgtacgcta atcagattgc ctttggcagg ctctaccggg aaaaactgaa
    54301 agagcaggtt gaggcgctgg gctatgaaac ggaagtggtg ggtaagcacg gtatgtggga
    54361 aatgccgggc gtaccggtgg aggccttttc cggacgctca cagactatcc gggagaccgt
    54421 cggggaggac gcctcgctga aatcccggga tgtggcggcg ctggatacgc gtaaatccaa
    54481 acagcacgtc gatcctgaaa tcaaaatgac cgagtggatg cagacgctga aggaaaccgg
    54541 gttcgatatc cgggcgtatc gtgacgcagc ggaacaacgg gcatataccc gcacgcagac
    54601 acccggacca gcttcacagg acgggccgga tgtgcagcag gcggtgacac aggcgattgc
    54661 cggattaagt gaacgcaaag tgcagtttac gtacacggac gtgctggcca ggacggtcgg
    54721 catactgccg ccggaagccg gtgtgattga gcgggcacgc gccggtatcg atgaggccat
    54781 cagccgtgag cagcttatcc ccctcgatcg tgagaagggg atgttcacgt ccgggattca
    54841 tgtgctcgat gagctgtcag tccgggcact cagtcgtgac atcatgaaac agaaccgggt
    54901 gaccgtacat ccggagaaaa gtgtcccccg gacggccggt tacagcgatg ccgtcagtgt
    54961 tctggcacag gatcgcccgt cgctggccat tgtgtccggg cagggcggtg cagccgggca
    55021 gcgtgagcgg gtggctgaac tggcaatgat ggcccgggag caggggcggg aggtgcagat
    55081 tatcgccgct gaccgtcgct cgcagatgaa cctgaagcag gatgaacggc tgtccggtga
    55141 gctgataacc ggacgtcgtc agctgcagga gggcatggcc ttcacgccgg gcagtaccgt
    55201 tatcgtcgac cagggcgaaa aactctccct gaaagagacg ttaaccctgc tggacggtgc
    55261 cgcacgtcat aacgtacagg tcctgataac cgacagcggg cagcgaaccg gtacaggcag
    55321 tgcgctgatg gccatgaagt atgccggggt gaacacgtat cgctggcagg gcggagaaca
    55381 gcgaccggca accatcatca gtgaaccgga ccggaatgtc cgctatgacc ggctggccgg
    55441 agattttgcg gccagcgtga aagccggaga agagagcgtg gcacaggtca gcggggtacg
    55501 ggaacaggcc atactgacac aggccattcg cagtgagctg aaaacacagg gcgtgctcgg
    55561 acacccggag gtgaccatga ccgccctgtc accggtctgg ctggacagcc ggagccgtta
    55621 tctgcgggat atgtaccgac cggggatggt gatggagcag tggaacccgg agacacgcag
    55681 tcatgaccgc tatgttatcg accgggtgac ggcgcagagt cacagcctga ccctgcggga
    55741 tgcgcagggc gaaacgcagg tggtgcgtat ttcctccctg gacagcagct ggtcgctgtt
    55801 ccggccggaa aaaatgccgg tggcagacgg cgagcgactg agggtgacag ggaaaattcc
    55861 cggactccgc gtctccggcg gtgaccgcct gcaggtggca tccgtcagtg aagatgcgat
    55921 gacggttgtt gtgccggggc gggctgaacc ggccaccctg cctgtggctg attcaccgtt
    55981 cacggcactg aagctggaga acggctgggt ggaaacgccc gggcattccg tcagtgacag
    56041 tgcgacggtg tttgcctccg tcacacagat ggcaatggac aacgccaccc tgaacggtct
    56101 ggcccgcagc ggtcgtgatg tccggctgta ttcctcactg gatgaaaccc gtactgcgga
    56161 aaaacttgcc cgccatccct cctttacggt ggtttctgag cagataaagg cgcgggccgg
    56221 tgagacatcg ctggaaaccg ctatcagtct gcagaaaacc gggctgcaca cgccggcaca
    56281 gcaggccatt catctggccc ttcctgtgct ggaaagtaaa aacctggcct tcagcatggt
    56341 ggacctgctg acagaggcga agtcgtttgc tgcagaagga accggtttta ctgaactggg
    56401 aggggaaatc aatgcgcaga taaaacgcgg tgacttactg tatgtggatg tggcaaaagg
    56461 ctatggcaca ggcctgctgg tttcccgtgc gtcgtatgag gcagaaaaaa gtattcttcg
    56521 ccatattctc gaaggtaagg aggcggtcac gccgctgatg gagagagtac ccggcgaact
    56581 catggagacg ttaacgtcgg gacagcgtgc cgccacccgt atgatactgg aaacgtccga
    56641 ccgtttcacg gtggtacagg gttatgccgg ggtgggtaag accacacagt tccgggcggt
    56701 gatgtcagcc gtgaacatgc tgccggagag tgagcgtccc cgtgtcgttg ggctggggcc
    56761 cacgcaccgt gcggtcgggg agatgcgcag cgccggcgtg gatgcacaga cactggcgtc
    56821 ctttctgcat gacacgcagc tgcagcagcg cagcggagaa acgccggatt tcagcaacac
    56881 gctgttcctg ctcgatgaga gctcaatggt gggcaatacc gacatggcac gggcatacgc
    56941 cctgattgcg gccggtggcg gtcgtgctgt ggccagcggt gacacggacc agctgcaggc
    57001 catcgcgccc ggtcagcctt tccgtctcca gcagacgcgc agtgctgccg atgtggccat
    57061 catgaaggag attgtgcgtc agacgccgga actgcgggag gcggtataca gcctgattaa
    57121 ccgggatgtg gaaaaggcac tgtccgggct tgagagtgtg aaaccgtctc aggtgccacg
    57181 tctggagggc gcatgggcac cggagcactc cgtgacggag ttcagtcaca gccaggaagc
    57241 gaaactggca gaagcgcagc agaaggcgat gctgaaaggc gaggctttcc cggatatccc
    57301 catgacactg tatgaagcca ttgtccgcga ctataccggc aggacaccgg aagcacggga
    57361 gcagacgctg attgtcacgc acctgaatga ggaccggcgc gtactgaaca gcatgattca
    57421 tgatgcacgg gaaaaggccg gtgagctggg gaaagagcag gtcatggtgc ctgtcctgaa
    57481 cacagcgaat atacgtgacg gggagctgcg tcgtctctcc acctgggaga ataacccgga
    57541 tgcccttgcc ctggtggata gtgtgtatca ccggattgcc ggtatcagca aggatgacgg
    57601 gctgataacc ctggaggatg cggaaggtaa cacgcggctg atttcgcccc gggaggcggt
    57661 ggctgaaggt gtcacactgt acaccccgga caaaatccgg gtggggaccg gcgaccggat
    57721 gcgcttcacg aagagtgacc gggagcgcgg ttatgtggcc aacagcgtct ggacggtgac
    57781 agcggtttcc ggtgacagtg tcacgctgtc agacggacag cagacccggg tgattcgccc
    57841 cggccaggag cgggcagagc aacatattga cctggcttat gccatcaccg cccacggtgc
    57901 gcagggggcg agtgaaacct ttgccatcgc gcttgaaggc acggaaggta accggaaact
    57961 gatggccggc tttgagtcag cctacgtggc cctgtcgcgt atgaagcagc atgtgcaggt
    58021 gtacaccgat aaccgtcagg gctggacgga tgccattaac aatgccgtac agaaaggaac
    58081 tgcccacgat gtgctggagc cgaaaccgga ccgggaggtc atgaatgcgc agcggctgtt
    58141 cagtacggca cgggaactgc gggacgtggc ggcaggccgt gccgttctcc gtcaggcggg
    58201 gctggccggg ggagacagtc ctgcacggtt tattgctccg ggacgtaaat atccgcaacc
    58261 gtatgtggca ctgccggctt ttgaccgtaa cggcaggtcc gccggtatct ggctgaaccc
    58321 actgaccacg gatgacggaa acgggctgcg gggattcagc ggtgaaggcc gtccgtggaa
    58381 tcccggtgcc atcaccggtg gccgcgtgtg gggggatatt ccggataaca gcgtccagcc
    58441 gggagccgga aatggtgaac cggtcacggc agaggtactg gcacagcggc aggctgaaga
    58501 ggccatccgc cgtgaaacgg aacgccgcgc agatgaaatt gtcaggaaaa tggcagagaa
    58561 caaacctgac ttgccggacg gcaaaacaga gctggctgtc agggatattg ccgggcagga
    58621 acgtgaccgg actgccactt ctgaacggga aaccgcactg ccggagagtg tgctgcgtga
    58681 atcacaacgg gaacgggaag cggtccggga ggttgcccgg gaaaatctgc tgcagaggct
    58741 tctgcagcag atggagcggg atatggttcg tgacctgcag aaagagaaaa ccctgggcgg
    58801 agactgatac aggaagacaa acactgatga caacggataa cacgaacacg atacgtaacg
    58861 attcactggc tgcacggacc gatacctggt tgcagtcatt tctggtctgg tcacccggac
    58921 agcgggatat catcaaaacg gtggcactgg tgctgatggt actggaccac atcaatctga
    58981 tattccagct gaagcaggaa tggatgtttc tggtcgggcg tggggccttt ccgctttttg
    59041 ccctggtgtg ggggctgaat ctgtcccgtc atgcgcatat ccggcaaccg gccattaacc
    59101 ggctgtgggg atggggaatt attgcccagt tcgcatatta tctggcaggc tttccctggt
    59161 atgaggggaa tatcctgttt gcctttgcag tggtggcaca ggtgctgacg tggtgtgaaa
    59221 cgcgcagtgg gtggcgtaca gcagcggcca ttctcctgat ggccctgtgg gggcctttgt
    59281 ccggcaccag ttacggcatt gccgggctgc tgatgctggc agtcagccac cggctgtacc
    59341 gggcggaaga cagagcggaa cgtctggcgc tggtcgcctg cctgctggct gttattccgg
    59401 cgcttaacct tgccaccagt gatgcagcgg cggtggctgg tcttgtgatg acggtgctga
    59461 ccgttggtct ggtgtcgtgt gcaggaaaat cattaccccg tttctggccc ggagactttt
    59521 tcccgacgtt ctatgcctgt catctggctg tgctgggcgt tctggcgctg tgacgggtgt
    59581 ggtatctttg gccgcaagag gatgattcgt cagaggcaga acacagcatg acagagcaga
    59641 agcgaccggt actgacactg aagcggaaga cagagggaac agcgcctgtc cgcagccgga
    59701 aaaccatcat caatgtcacc acgccaccaa aatggaaggt gaaaaagcag aaactggccg
    59761 agaaagcggc ccgggaagca gagctggcgg caaaaaaagc gcaggccaga caggcgctgt
    59821 ccatttatct gaacctgccc tcactggatg aggccgtgaa taccctgaag ccctggtggc
    59881 cgggattatt tgacggtgac acgccccggc ttctggcctg cggtatccgg gacgtgttac
    59941 tggaagacgt ggcgcagcgg aatatcccgc tctcgcataa aaaactgcgc agggcgctga
    60001 aggccatcac ccgttcagaa agctatctgt gtgccatgaa agccggtgcc tgccggtatg
    60061 acacggaagg gtatgtgacg gagcatattt ctcaggagga ggaaacgtat gcggcagagc
    60121 gtctggataa aatccgccgc cagaaccgga taaaggcaga acttcaggcc gtgcttgatg
    60181 agaaataaaa aaaagcctcc ctcagagaga ggaggcaggg aaataaggct taaaaggaaa
    60241 taacttccgt acccgaaagg aagccaattc agtagattat ttaacaccat aatactgacg
    60301 ggttaaagag gagtgataaa gatgaatgga ttcagaaaca gttcacggaa cggtcaggtc
    60361 tggtgctggc agcgtgccgg aagccgggcc gttattctgg aggtcagtgg acgctggatg
    60421 gaagcggcag aaggatggcg acgggctgcc tgtgttgcgc cccggacaga ctggcagcag
    60481 tttgcccgaa aaagggctga acactgccac cggcgctgcc ggggaagggt gtaacgaaaa
    60541 aagcagcctt cattactcca gggattcaga aggctgaata atgcatgaga tttgcttttt
    60601 ttaatatccg gtcgggcagt atgaccggac agttctgagt agcacagagt tttttccgta
    60661 ttaagtcgtg attttatatt ttgtgattaa tttcacaaaa taaggtgtta ttcagtgtgt
    60721 gctgcaatat tcaggatgcc tgaaatacag gtgctattta tctgatatgg agaataacat
    60781 gaggaaatat attccactgg tattatttat cttttcatgg gtaatgactc caacttattg
    60841 atagtgtttt atgttcagat aatgcccgat gactttgtca tgcagctcca ccgattttga
    60901 gaacgacagc gacttccgtc ccagtgtaac cggctcattt aaaccgtctg gtctgtttcc
    60961 tccggctcta caaaaataat gtccatcatt tttaatggac actatcgtat gaaacaccgg
    61021 acctggatca ctgaagcttt acgtcttcac tttgaagaac atttaccccg ggttgtggcc
    61081 gggcgtcgcc tgggtgtacc aaaatcaaca gtttgtagta tgttcgtgcg ctttcggaga
    61141 gctggccttt cgtggccttt gcccgcaggc atgtcggagc aggaacttga tgcctgcctt
    61201 tacggacaat tttccacggt accagtcgta cgtcctgaaa gcaccgttat atccgaagcc
    61261 cccgtggtaa aaaaacgtcc ccggcggccc aacttccctt atgagtttaa aatcgcctta
    61321 gtggagcagt cactgcagcc cggagcctgt gtggcgcaga tcgcccggga aaacggaatc
    61381 aacgataacc tgctcttcaa ctggcgccat caataccgga aaggtggcct gctgccttcc
    61441 ggaaaaaata tgccggcact gcttcccgtg acgttaacgc cggagccgga taataaaatc
    61501 ccggcccccg cacaggaacc agagcagata aatacaccgt ccgacagtct gtgttgtgag
    61561 ctggttctgc cggccggaac tctcaggctt aaaggtaaac tgacgccggc gttattacag
    61621 acacttatcc gcgaaataaa agggagcagc cactgatgat atctctccct gcaggttcgc
    61681 gtatctggct ggttgcaggt atcaccgata tgcgaaatgg ctttaacggc ctggcatcaa
    61741 aagttcagaa cgtcctgaag gatgacccgt tctccggaca cctgttcatc ttccgcggac
    61801 gccggggtga ccagataaaa gtgttgtggg ctgacagtga cggactgtgc ctcttcacca
    61861 aacgcctgga gcggggccgc ttcgtctggc cagtcacccg tgacggcaag gtgcacctta
    61921 ctccggctca gttatccatg cttcttgaag gtatcaactg gaagcacccg aaacgaacgg
    61981 aacgcgctgg aatccgcata taacccgttg taaagtgagg atatggacac ctcacttgct
    62041 catgagaacg cccgcctgcg ggcactgttg cagacgcaac aggacaccat ccgccagatg
    62101 gctgaataca accgcctgct ctcacagcgg gtggcggctt atgcttccga aatcaaccgg
    62161 ctgaaggcgc tggttgcgaa actgcaacgt atgcagttcg gtaaaagctc agaaaaactt
    62221 cgtgcaaaaa ccgaacggca gatacaggaa gcacaggagc gaatcagcgc acttcaggaa
    62281 gaaatggcgg aaacgctggg tgagcaatat gacccggtac tgccatccgc cctgcgccag
    62341 tcttcagccc gtaaaccgtt accggcctca cttccccgtg aaacccgggt tatccggccg
    62401 gaagaggaat gctgtcctgc ctgtggtggt gaactcagtt ctctgggatg tgatgtgtca
    62461 gagcaactgg agcttatcag cagcgccttt aaggttatcg aaacacaacg tccgaaacag
    62521 gcctgttgcc ggtgcgacca tatcgtgcag gcaccagtac cttcaaaacc cattgcacgc
    62581 agttatgccg gagcggggct tctggcccat gttgtcaccg ggaaatatgc agaccatctg
    62641 ccgttatacc gccagtcaga aatataccgt cgtcagggag tggagctgag ccgtgccaca
    62701 ctggggcgct ggacaggtgc tgttgctgaa ctgctggagc cgctgtatga cgtcctgcgc
    62761 cagtatgtgc tgatgcccgg taaagtccat gctgatgata tccccgtccc ggtccaggag
    62821 ccgggcagcg gtaaaacccg gacagcccgg ctgtgggtct acgtccgtga tgaccgtaac
    62881 gccggttcac agatgccccc ggcggtctgg ttcgcgtaca gtccggaccg gaaaggtatc
    62941 catccacaaa attacctggc cggttacagc ggtgtgcttc aggccgatgc ttacggtggt
    63001 taccgggcgt tatacgaatc cggcagaata acggaagccg cgtgtatggc tcatgcccgg
    63061 agaaaaatcc acgatgtgca tgcaagagcg cccacctaca tcaccacgga agccctgcag
    63121 cgtatcggtg aactgtatgc catcgaggca gaggtccggg gctgttcagc agaacagcgt
    63181 ctggcggcaa gaaaagccag agccgcgcca ctgatgcagt cactgtatga ctggatacag
    63241 caacagatga aaacactgtc gcgtcactca gatacggcaa aagcgttcgc atacctgctg
    63301 aaacagtggg atgcactgaa cgtgtactgc agtaatggct gggtggaaat cgacaacaac
    63361 atcgcagaga acgccttacg gggagtggcc gtaggccgga aaaactggat gttcgcgggt
    63421 tccgacagcg gtggtgaaca tgcggcggtg ttgtactcgc tgatcggcac atgccgtctg
    63481 aacaatgtgg agccagaaaa gtggctgcgt tacgtcattg aacatatcca ggactggccg
    63541 gcaaaccggg tacgcgatct gttgccctgg aaagttgatc tgagctctca gtaaatatca
    63601 atacggttct gatgagtcgc ttacgtccca gtcgtcccag ccgtgccagg tgctgccaca
    63661 gattcaggtt atgccgctca attcgctgcg tatatcgctt gctgattacg tgcagctttc
    63721 ccttcaggcg ggattcatac agcggccagc catccgtcat ccatatcacc acgtcaaagg
    63781 gtgacagcag gctcataaga cgccccagcg tcgccatagt gcgttcaccg aatacgtgcg
    63841 caacaaccgt cttccggag
//
LOCUS       DAFGPF010000013        63293 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFGPF010000013 DAFGPF010000000
VERSION     DAFGPF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 63293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63293
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.013"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            221..1309
                     /gene="ompF"
                     /locus_tag="LSX49_001012"
     CDS             221..1309
                     /gene="ompF"
                     /locus_tag="LSX49_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HBL7167449.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKGNGEDSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNK
                     TRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADR
                     TNLQEESPLGKGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKT
                     QDVLLVAQYQFDFGLRPSIAYTKSKAKDVDGIGDVDLVNYFEVGATYYFNKNMSTYVD
                     YIINQIDSDNKLGVGSDDTVAVGIVYQF"
     gene            1494..2684
                     /gene="aspC"
                     /locus_tag="LSX49_001013"
     CDS             1494..2684
                     /gene="aspC"
                     /locus_tag="LSX49_001013"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HBL7167450.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAALHKELIVASSYSKNFGLYNERVGACTLVAADSETVERAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(2734..3381)
                     /gene="gloC"
                     /locus_tag="LSX49_001014"
     CDS             complement(2734..3381)
                     /gene="gloC"
                     /locus_tag="LSX49_001014"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HBL7167451.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDA
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFNEQARLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW"
     gene            complement(3408..3956)
                     /locus_tag="LSX49_001015"
     CDS             complement(3408..3956)
                     /locus_tag="LSX49_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HBL7167452.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            complement(4137..5984)
                     /gene="ldtD"
                     /locus_tag="LSX49_001016"
     CDS             complement(4137..5984)
                     /gene="ldtD"
                     /locus_tag="LSX49_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HBL7167453.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLSDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDAVVSPSAVTVETAETKLMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            complement(6245..10705)
                     /gene="mukB"
                     /locus_tag="LSX49_001017"
     CDS             complement(6245..10705)
                     /gene="mukB"
                     /locus_tag="LSX49_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HBL7167454.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVWKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQDVTEFLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLNQYNQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS"
     gene            complement(10705..11409)
                     /gene="mukE"
                     /locus_tag="LSX49_001018"
     CDS             complement(10705..11409)
                     /gene="mukE"
                     /locus_tag="LSX49_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HBL7167455.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEESQPDSGEEE"
     gene            complement(11390..12712)
                     /gene="mukF"
                     /locus_tag="LSX49_001019"
     CDS             complement(11390..12712)
                     /gene="mukF"
                     /locus_tag="LSX49_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HBL7167456.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMVLR
                     DEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            complement(12709..13494)
                     /gene="cmoM"
                     /locus_tag="LSX49_001020"
     CDS             complement(12709..13494)
                     /gene="cmoM"
                     /locus_tag="LSX49_001020"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HBL7167457.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEIGPQ
                     KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQILGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            13630..14409
                     /gene="elyC"
                     /locus_tag="LSX49_001021"
     CDS             13630..14409
                     /gene="elyC"
                     /locus_tag="LSX49_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HBL7167458.1"
                     /translation="MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGSSGEPRQE"
     gene            complement(14386..15279)
                     /locus_tag="LSX49_001022"
     CDS             complement(14386..15279)
                     /locus_tag="LSX49_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HBL7167459.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     ARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
                     QFNNTGLSMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFNRRNFDLASKSLLPWLA"
     gene            complement(15433..16179)
                     /gene="kdsB"
                     /locus_tag="LSX49_001023"
     CDS             complement(15433..16179)
                     /gene="kdsB"
                     /locus_tag="LSX49_001023"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HBL7167460.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAKDLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAQEVPGTGVDTPEDLERVRAEMR"
     gene            complement(16176..16358)
                     /gene="ycaR"
                     /locus_tag="LSX49_001024"
     CDS             complement(16176..16358)
                     /gene="ycaR"
                     /locus_tag="LSX49_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HBL7167461.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADEGKS"
     gene            complement(16410..17642)
                     /locus_tag="LSX49_001025"
     CDS             complement(16410..17642)
                     /locus_tag="LSX49_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaQ family DNA glycosylase"
                     /protein_id="HBL7167462.1"
                     /translation="MSLPHLSLADARNLHLAAQGLLNKPHRRASLEDIPATISRMSLL
                     QIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGELMEYWAHEACFMPRSDFRLIRH
                     RMLAPEKMGWKYKDAWMQEHAAEIALLIQHIHDRGPVRSADFEHPRKGASGWWEWKPH
                     KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQAEAEIIMLDNSARS
                     LGIFREQWLADYYRLKRPALAAWREARAEQQQIIAVHVEKLGNLWLHADLLPLLERAL
                     AGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKRQYGYFVLPLLHRGQ
                     LVGRMDSKMHRQKGILEVISLWLQEGIKPTTTLQKGLRQAITDFANWQQATRVTLGRC
                     SQGLFTDCRAGWEIDPVA"
     gene            complement(17679..18665)
                     /gene="lpxK"
                     /locus_tag="LSX49_001026"
     CDS             complement(17679..18665)
                     /gene="lpxK"
                     /locus_tag="LSX49_001026"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HBL7167463.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTGAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKLVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVAQLEHVVAIAGIGHPPRFFATLKMCGVQPEKCVPLADHQFLNHADVSALV
                     SAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGN"
     gene            complement(18662..20410)
                     /gene="msbA"
                     /locus_tag="LSX49_001027"
     CDS             complement(18662..20410)
                     /gene="msbA"
                     /locus_tag="LSX49_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HBL7167464.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLMWMPLVVIGLMILRGITSYISSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            complement(20447..22711)
                     /locus_tag="LSX49_001028"
     CDS             complement(20447..22711)
                     /locus_tag="LSX49_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309023.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HBL7167465.1"
                     /translation="MKITTVGVCIICGIFPLLILPQLPGTVTLAFLTLFACVLAFIPV
                     KTVRYIALTLLFFVWGILAAKQILWAGETLTGATQDAIVEIIATDGMTTHYGQITHLQ
                     GRRIFPAPGLVLYGEYLPQAVCAGQVWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYMWNAVILGLGMGERLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRGGQVFLPGCWLHWQMPLIGGICCAAFYAWLTG
                     MQPPALRTVVALAIWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANL
                     FAIPLVTFITVPLILAAMVVHLSGPFILEQGLWFLADRSLALLFWGLKSLPEGWINIA
                     ERWQWLTFSPWFLLVVWRLNAWRTLPAMCVAVGLLMCLPLWQKPRPDEWQVYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGSNDKGNNHSCVVK
                     IDDGTNSILLTGDIEAPAEQKMLSRYWQQMQATLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSSKVKYRYHQQGYKWLDTPHQGQITVNFSAQGWWISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            complement(22917..23201)
                     /gene="ihfB"
                     /locus_tag="LSX49_001029"
     CDS             complement(22917..23201)
                     /gene="ihfB"
                     /locus_tag="LSX49_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HBL7167466.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            complement(23361..25034)
                     /gene="rpsA"
                     /locus_tag="LSX49_001030"
     CDS             complement(23361..25034)
                     /gene="rpsA"
                     /locus_tag="LSX49_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBL7167467.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            complement(25145..25828)
                     /gene="cmk"
                     /locus_tag="LSX49_001031"
     CDS             complement(25145..25828)
                     /gene="cmk"
                     /locus_tag="LSX49_001031"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBL7167468.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQ
                     YARQKLALA"
     gene            complement(26001..26783)
                     /gene="ycaL"
                     /locus_tag="LSX49_001032"
     CDS             complement(26001..26783)
                     /gene="ycaL"
                     /locus_tag="LSX49_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase YcaL"
                     /protein_id="HBL7167469.1"
                     /translation="MYLKSNQKNTKLLLAIATSAALLTGCQNTHGINTDLAISSGLNA
                     YKAATLSDADAKAIANQGCVEMDSGNKVASKSSKYGKRLAKIAKALGNNINGTPVNYK
                     VYMTSDVNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAI
                     VAARDAISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQ
                     GLVGSFEKLASLDGGHTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            complement(26927..27316)
                     /locus_tag="LSX49_001033"
     CDS             complement(26927..27316)
                     /locus_tag="LSX49_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL7167470.1"
                     /translation="MSDLNQFRSKGPELLVELAQHTSETVREIIDIEPEVADQIGQAV
                     ANRMMQVWGGQNVYFPMGMVWKVSQRDREIFREFNGRNHHELARKFGVSLQWVYSVVK
                     RVRKEELDRMQGKLFADEPDADTEKKE"
     gene            complement(27288..27737)
                     /locus_tag="LSX49_001034"
     CDS             complement(27288..27737)
                     /locus_tag="LSX49_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein GemA"
                     /protein_id="HBL7167471.1"
                     /translation="MQKKRLIQLIHIARNELGMDEDTYRQMLQGLTGKASTKGMDTTQ
                     LNCVLESMKKKGFRVKPARKASSGLPLDNHPQSRKIRALWLEMAAAGIVRDRSENALA
                     RWIKRETGISALRWLSTEQASSVIEKLKKWQRRAAGVKHERPESVSK"
     gene            complement(27739..27945)
                     /locus_tag="LSX49_001035"
     CDS             complement(27739..27945)
                     /locus_tag="LSX49_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001489320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167472.1"
                     /translation="MTTETIVCFLFWYMYAGSCSARLHRSLGYGRHYDTAHYILYMTA
                     VMLFWPVTLPAATDIVADRLKKRR"
     gene            complement(27935..28165)
                     /locus_tag="LSX49_001036"
     CDS             complement(27935..28165)
                     /locus_tag="LSX49_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167473.1"
                     /translation="MITLSGKSRKLKACRISARYLFARAFFKNVRPGITIGVIAGREQ
                     VEKYMSGAWWNNDPVIAARNIHIEWGGIQNDY"
     gene            complement(28162..28845)
                     /locus_tag="LSX49_001037"
     CDS             complement(28162..28845)
                     /locus_tag="LSX49_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HBL7167474.1"
                     /translation="MTDQNKHIEKLKKLLALAASGNPHEAALALRRARKLMDVHGITH
                     SDIAMSDIDETISHYWPTGSLRPPRYMLGLMNIIREVFGVNSIIHPGTHPSVGFYGNR
                     ERAALAAYTWEVLARQLKKARQQYISAQNKRIKTATRTSRGDQFAEGWVLAVISEIQS
                     FALTDDERELMQQWLEHKYPQTQTTRARKPGRSRNGDASRYAGFREGQNVRLHRPVSG
                     QEQQKLEAR"
     gene            complement(28842..29057)
                     /locus_tag="LSX49_001038"
     CDS             complement(28842..29057)
                     /locus_tag="LSX49_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167475.1"
                     /translation="MADILREITAWTLILTGLATCLSAGAALAALLMHITTQWLWEKL
                     KAAYSLKELSDAVRAWKRQKNTGDTEQ"
     gene            complement(29072..29368)
                     /locus_tag="LSX49_001039"
     CDS             complement(29072..29368)
                     /locus_tag="LSX49_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167476.1"
                     /translation="MTRNTELTRTALYRLALQRFGPDAQALKLAEEAAELAASAARNL
                     NGQGSESDLAAELADVEIMTEQLRLQGMDRLIDFHKQKKLERLAARLGVIYTNE"
     gene            complement(29378..29650)
                     /locus_tag="LSX49_001040"
     CDS             complement(29378..29650)
                     /locus_tag="LSX49_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167477.1"
                     /translation="MITPQEARQRTRTLVEHYVNECECRDLTDVKHVLTALISMATQA
                     IVATNGKEAALQVLMNTLTHTAEHEVPYRMETTAEGGLHITVSRKH"
     gene            complement(29939..30469)
                     /locus_tag="LSX49_001041"
     CDS             complement(29939..30469)
                     /locus_tag="LSX49_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="HBL7167478.1"
                     /translation="MAKSTKGAKRIKAAAALWVPGTREEVIEGIRLLGDAQRELVRAE
                     TEMNDAIGDITARYAPLTESLKKRMAELQSGIQTWCEAHRDELTGNGKVKFANLTTGE
                     VQWRNRPPSVSIRGADNVIELLRRLGLERFIRVKEEINKDAILNEKEAVKNIPGISIK
                     SDIEDFSIIPFEQDVQ"
     gene            complement(30497..30766)
                     /locus_tag="LSX49_001042"
     CDS             complement(30497..30766)
                     /locus_tag="LSX49_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167479.1"
                     /translation="MKSTTGINQQISKVQSAIMALKATNTDVQSITIRGNKPVIRVSR
                     SAHCMRMLEQGKACYLYTGHDHRGYFRQGVFELHGCRVVWPESLW"
     gene            complement(30769..31935)
                     /locus_tag="LSX49_001043"
     CDS             complement(30769..31935)
                     /locus_tag="LSX49_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7167480.1"
                     /translation="MLVLKQQLKEARIPQAVVARAVDVSEATLAQIVNHNAWPRTSPG
                     EVRRRLASWLESQGIDTTKSFDAVQGAATPRTAGTTDKTSLSEEENMLLKKQVLFPAT
                     KKAFGLFRDPFADEAMQGSDDVFTTPDIRYVREALYQTARHGGFMAVIGESGAGKSTL
                     RRDLTERINRENAPVIVIEPYIIAMEDNDVKGKTLKAAAIAEAIISTIAPLESIRRSQ
                     DARFRQLHRVLKDSSQAGFSHVLVIEEAHSLPIPTLKHLKRFFELESGFKKLLSIVLI
                     GQPELATKLSERNMEVREVVQRCEVVELLPLDNNLEEFLTFKLQRAGKQLTDIMDAGA
                     VDAIRARLSNPGSHRKNMVSLLYPLAVSNLVIAAMNLAAEIGVPQVNADVVKGV"
     gene            complement(31946..33715)
                     /locus_tag="LSX49_001044"
     CDS             complement(31946..33715)
                     /locus_tag="LSX49_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBL7167481.1"
                     /translation="MTPALTEKLVETARAARDAGHGKRGAIYDAACAELGMSRATLLR
                     RLKEVSVTDKRKKRADAGRSALTRDEAALISATLREATRKNGKRLYSIADAVETLRAN
                     GFITAGRTDETTSEFFPLSEDAISRALRNYGLHPEQLDAPAPHTEVASLHPNHVWQID
                     ASLCTLYYLSNGHKGLQVMDSAKFYKNKPANLARIASDRVWSYEITDHASGWIYVEYV
                     TGAESGENLCSVLINAMQERGGADVLHGVPKILYLDPGSANTAGMTKNMCRSLGIDLI
                     AHKPHNARATGQVEKARDIIERKLEPGLKFRPVHSLEELNALAAKWRSHFNATAVHSR
                     HGKTRTDIWLKITAEQLKKAPSVEVCRELAVAAPELRKVTPKLRVSFRGTEFDVSTVP
                     GVLVGEKLMITRNPWRSDVAQVVLTGEDGHETFFLVEEVRKNEFGFAEGAAVFGESYK
                     ALPETPAQMAAKETEALVTGTDNAADAAAARKAKALPFGGRLDPYKHIDDTTLPAYMP
                     KRGQASDVRGPRTEQRPMTHVEAAKALRDKFSADGLTWTPEHYRQLTAQYPDGVPEAA
                     LDEVMATLTTPARSSVISIVNGN"
     gene            complement(33731..34048)
                     /locus_tag="LSX49_001045"
     CDS             complement(33731..34048)
                     /locus_tag="LSX49_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167482.1"
                     /translation="MNTNNTQNTLMDSPEALGHALCNLLPEMVQGFRVVTPSGEICVP
                     AQETHPFVLTMEVMLMQQIRRLQNQSALRPVVAPQPVNTVVKTCDGETLCDLARKIAA
                     RIG"
     gene            complement(34048..34968)
                     /locus_tag="LSX49_001046"
     CDS             complement(34048..34968)
                     /locus_tag="LSX49_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001488438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3102 domain-containing protein"
                     /protein_id="HBL7167483.1"
                     /translation="MGRTKSPINTELNADVPLSDDLNVSLNAMTQHRMEIMQQFGDGL
                     PYERERIVHEARFYMAQSAESMLEAGKRLIILKENEPHGDFTNILENDLGLAPQVARR
                     MMQASVKFLGNGDEQPKRSALSVLGKTKLYELMVLDDEELDALADGGTVAGATLDDID
                     RMTSRELKAALREARETNAAQQQVLAGKDEKINELATKLEKKSRLQPPPPDEELKKLR
                     AEVTALAVEAESAIAVRLSSVFETLCEYCTKNMIDTPRDFMAGLVCQIERSVHALRET
                     FDLEAAPSGNDAPAWLTEPEPEINRPEDMQ"
     gene            complement(34979..35287)
                     /locus_tag="LSX49_001047"
     CDS             complement(34979..35287)
                     /locus_tag="LSX49_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7167484.1"
                     /translation="MSKTNVSSSGSRILRVLKALRGHALNGISNGELATALHESPANI
                     NRALNTLIEEGLALKLENGRFAPGIQLLQIAMAHSNEMARAQDRINEINQRVISGSRL
                     "
     gene            complement(35340..35528)
                     /locus_tag="LSX49_001048"
     CDS             complement(35340..35528)
                     /locus_tag="LSX49_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001510316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL7167485.1"
                     /translation="MTAEQVKALFRQRGITFTRWAEENGYNRNEVYRVLNGQTKARYG
                     KSHEIAVKLGLKSTAQAA"
     gene            35622..35978
                     /locus_tag="LSX49_001049"
     CDS             35622..35978
                     /locus_tag="LSX49_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7167486.1"
                     /translation="MSKDIGERVISVRKKAGLNQREFAARLGISNGGISQIENGKAMP
                     GGEFLLKMHQEFNVDVNWLLTGMSTDGMTRNQNQISPEKQKLIDTFDDMTPDQQRSFL
                     EIGRFYTQPKPGKIAG"
     gene            complement(36095..36859)
                     /locus_tag="LSX49_001050"
     CDS             complement(36095..36859)
                     /locus_tag="LSX49_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HBL7167487.1"
                     /translation="MKMQTLPIVPWIGGKRRLAKHILPLFPAHECYVEPFCGAAALYF
                     LKTPGKIEVINDINGELVNLYRVVKHHLEEFVRQFKWALVSRQIYKWLQITPEETLTD
                     IQRAARFYYLQKQAFGGKVAEHSFGTSTTSPPRFNLLRIEEELSAAHLRLSRTVIEHM
                     DWQQCIERYDRPHTLFYCDPPYLGTEGYGVDFPEGNYSRLAELARCIRGKMIISVNDI
                     PQMREVFTGLNIQTVNINYSLAGKPTPRRELLICNF"
     gene            complement(37050..37265)
                     /locus_tag="LSX49_001051"
     CDS             complement(37050..37265)
                     /locus_tag="LSX49_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167488.1"
                     /translation="MNPRLTLTEHQRRAEAVNNVLEDIIRLYRGELSVCRAAFHFQGI
                     QKQFDTSVFAEGITYALDRIRSENRPG"
     gene            37267..37668
                     /locus_tag="LSX49_001052"
     CDS             37267..37668
                     /locus_tag="LSX49_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001534496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167489.1"
                     /translation="MHSLNDDFYVLTGKIFCRLLNTHPAPQVLIYSGFFDIPDQVDHD
                     QKKCRCFIDTLIWLRDNSYIRYSQLLAVGAADVVLTEKTLCLLNAMPTFLQPRPVPFK
                     ESLLDAVKTGENAVIAECVSRIMRYVFNERK"
     gene            complement(37644..38372)
                     /locus_tag="LSX49_001053"
     CDS             complement(37644..38372)
                     /locus_tag="LSX49_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167490.1"
                     /translation="MTQTLNPVITVTVSGPVGSGKSYVLARIEEVVKQEFGNSVIVDA
                     ADVDGERRMSGDDLSTWQKPRAGTVIRLEEYTGQGLLSYGEERICRTNELLDVICPTG
                     RQPWILPDALHATIAALMTVYDQELLMKELRKLTGQSTECCSSPKYGKQEHIPINQPP
                     RFFDEYLLTPENKAEHEEIKAALFREIRKIAEMQLEGGLDRVMARGEWASLFERVSPE
                     LLPLALAIGIMQTADKPHLRSLNT"
     gene            38503..38853
                     /locus_tag="LSX49_001054"
     CDS             38503..38853
                     /locus_tag="LSX49_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin"
                     /protein_id="HBL7167491.1"
                     /translation="MKNLKKFIPPVKKPRLSGWLLTSVLLLGTIALVSPQQLPVVIYK
                     LALITLAAVLGYWLDRSLFPKARPGQYLKHDDRLMAEGRFPVQTGLHLVFSAALIRRA
                     LIVAAVCLAVAMGL"
     gene            38856..39596
                     /locus_tag="LSX49_001055"
     CDS             38856..39596
                     /locus_tag="LSX49_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HBL7167492.1"
                     /translation="MNWPQITWIVCMSLKLAFEAFRVFIRTERLSVRAGTFLVHMAWV
                     FFVAMLLWCGGFFSQACAAQPPQAALQYRDDVIRNARLEWGLSAPVADFAAQLHQESG
                     WRPDAISPAGAQGLAQFMPATADWISQLIPMLSSREPFNPAWAIRALVSYDRWLWQRV
                     SAASDCERMAMTLSGYNGGLGWVQRDRRLASQKGLDSTRWFGHVATVNAGRNAASWRE
                     NRHYPQRILRELAPRYLTWGGSSCVASG"
     gene            39580..40230
                     /locus_tag="LSX49_001056"
     CDS             39580..40230
                     /locus_tag="LSX49_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000264665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167493.1"
                     /translation="MWHLVKKLPWRGILLAILINAFLVGLYAMGYRSGHDSAKRDGDT
                     ALSQLQSAFDAYKTEQATLENAALRAWARRYQEQVAAGQRAEAGYLEQIAQLESRNKQ
                     LQGQINDVTQRWIDEKGKSHPIECVFTRGFVRQYNAALGYDNASVDTGHSDSVAATGT
                     RSGTATGQPETTDTRLRDSGVSQRDVLANIIDNAWQCRRWRNQINALLDEREGLQK"
     gene            40227..40553
                     /locus_tag="LSX49_001057"
     CDS             40227..40553
                     /locus_tag="LSX49_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167494.1"
                     /translation="MTLQVEFWTVVSFLLTFMRFVGGLAKWLFSKTEERQAARFASLE
                     QALQQSASNWGELEKEFMRFKADLPLNYVRREDYIRGQTVIEAKLDALYNKLEVVQQY
                     RNTGGQ"
     gene            40553..40864
                     /locus_tag="LSX49_001058"
     CDS             40553..40864
                     /locus_tag="LSX49_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167495.1"
                     /translation="MVDITRVRRESLRWSLLVALNKTRPYTASETLLLDVSRAIYPDT
                     TPLELRRELDYLADRKMVELEKKPSGDWFADLTRLGVDLVEYTVECGPGIARPEKYWS
                     E"
     gene            40864..41409
                     /locus_tag="LSX49_001059"
     CDS             40864..41409
                     /locus_tag="LSX49_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3486 family protein"
                     /protein_id="HBL7167496.1"
                     /translation="MARRSTIEKLPEDVRRWLERALTESGFSGYNELESLLRERGYVI
                     SKSAIHRYGQKIERRYGAIRAATEAARMLTEGAADDQDARSEAVIALIQTELFESIVQ
                     LQEAEEGEVDPKERVALLSKVAKNVATLSRASVNLKKFQSEVRARAQQAASNAEKIAR
                     KGGLSSDAVQALRREILGIAT"
     gene            41460..43001
                     /locus_tag="LSX49_001060"
     CDS             41460..43001
                     /locus_tag="LSX49_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167497.1"
                     /translation="MSPMDGRNNLAPVLPDTSALDAPPVLLPYQQRWVADTSPLKVIE
                     KSRRTGITWAEASDNVLTAASSAPAGGMNVYYIAYNQDMTVEYIQACAMWARAFNYAA
                     SEIEEGFWEEDDDDKHIKTYTIKFPDSGFRIVALSSRPSNLRGRQGIIVIDEAAFHEQ
                     LDELLKAALAMLIWGGKVRVISTHDGDDNPFNTLIGDIRAGRQGGSIHRITFREAVSE
                     GLFRRVCLRTGKEWSEASEQAWMASVYKFYGAGASEELDCIPANGGGAWLSRALIESR
                     MSADTPVLRLTCKEGYELLSDEVRFRETQDWLDEYLKPLLEALPTDARSFLGRDFGRS
                     GDLSVDYPLLQEKNLVRRVPFVLELRNVPFRQQEQITWYLMDGLPGLLGAAFDARGNG
                     AYLAEYAMQRYGSGRVQQVMPTEGWYREHMPPVKAALEDGNLVDLPKDEDTLDDLRAV
                     QVVNGVPRVPEQRSKAKADGGKRHGDSAIALALAYFASREINKGPVKASSRRRRQAAR
                     MLEGF"
     gene            43001..44497
                     /locus_tag="LSX49_001061"
     CDS             43001..44497
                     /locus_tag="LSX49_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF935 domain-containing protein"
                     /protein_id="HBL7167498.1"
                     /translation="MARGIWVSPDEFVAFSEPQKSLTAQIASRSRAIDFYGLGMYLPN
                     PDPILKAQGRDIRIYRELRTDPLVGGCIRRRKAALKSLERGLERGHASARVFRFIRDM
                     LDDLDLSRIIGEMSDAVLYGYQPCEIMWGRSVRSWAVTDIVGKPPEWFQFDTDNCLRF
                     RARDAGVEGELLSPSKFVVPAQDASYDNPYGFPDLSMCFWPVAFKKGGMKFWLRFAEK
                     FGSPWVIGKHPRGANDAEIEKLLDSMEQMVEDAVAAIPDDSSIELRAADGKADSSEVF
                     RELITLSRSEISIALLGQNQTTEANSNKASAQAGLEVTADIRDADADIIQAAVNQVIR
                     TVVTLNFGDVPCPVWAMWEQEAIDDTRATRDEKLTRAGLRLTPQYFKREYQLQDGDID
                     ETPPSERQNNMLPLSFAEAIDADIQAQQQLDDALDILMNGGALNGTLEPVLAPLFRRV
                     ENGVNPSELLGELAELYPQMNTDDLQERLARILFVANIRGRLHERDNG"
     gene            44478..45299
                     /locus_tag="LSX49_001062"
     CDS             44478..45299
                     /locus_tag="LSX49_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBL7167499.1"
                     /translation="MSVTTAELAYCMTLPPKRAINYLKSKGYQITWDWEEMWQEAHAR
                     AFTVAKVTRLDILEDIRGALQQAVDEGKTDRWFRQELEPVLKRKGWWGPRDTTDPVTG
                     EPVTIQQGSPWRLDTIFRTNMSVLYSAGRWAEQMENVDDRPYWMYTGINDSHTRRSHL
                     ALHGLVLRWDDPFWQAFYPPNGWRCRCSVIALSAADVRARGLKVISSGSAMGQELKLV
                     SEKTGEMRNVATFNTGTTKVTTDVGWSYAPGAAYRPDLARYQGTLQPLAQQELRG"
     gene            45302..45760
                     /locus_tag="LSX49_001063"
     CDS             45302..45760
                     /locus_tag="LSX49_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000135514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HBL7167500.1"
                     /translation="MASDNLVSITINDKSLRRSLRALDLAATDLEPAMRKIAGTLLAE
                     TQFNFLDEGRPGWMPSLAAEERDGQTLQDTGRLMGSVSTDHDDRQAVVGTNVVYGAIH
                     QFGGKTGRNESVELPARPFLPVTGDGELQPEVVIPILDTIVRHLESAARR"
     gene            45975..47090
                     /locus_tag="LSX49_001064"
     CDS             45975..47090
                     /locus_tag="LSX49_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL7167501.1"
                     /translation="MSAIHIFKAGTHTDMHGKKLPFTPDDLAACVKAYDPSVHEAPLV
                     IGHPRTEDPAWGWVKALSLSGVDLMAEPAQLDPQFAEMVTDGRFKKVSASFYLPDSPS
                     NPKPGVLYLRHVGFLGAQPPSVKGLKQVSFSEQEEGVVEFADWQAITNASLWGKLRDF
                     LIARFSLDEAEKVLPEWQLNSLREEAYRDTLSQDAAGAQFSETGPGPSSASNEESSMT
                     KEEIEALQEENRRLKQQAADRDARDAQVRQEQLHKDNVAFAEKLVAEGRLAPRASSVV
                     VALLDAVAGGDKPVEFAEGESRTPLATAFRSLLSDGEPVMNFAEQATKERVGDTVKVD
                     VAEFAEADPERLALHQKAVALSKKEGISYEAAVARCL"
     gene            47105..48058
                     /locus_tag="LSX49_001065"
     CDS             47105..48058
                     /locus_tag="LSX49_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167502.1"
                     /translation="MSDYLKGKRVVDPVLTSIARGYKNAAFIGERIFPVVLTDKEGVR
                     VPTFGKTAFVEYDTERAVGADSNVLVREKTGTLDLVLGEHDLAAPVDYREQAESMFNE
                     ESKAIRRATNGVNLRRELIAARLAQDEKVYRTGHVKKLTASDRWAGGKGDPIGVIEAG
                     MEAVRTATGLRPNLMTMGAGVMALLKFHPAIQAAIGANERKRITTEILQDLFQIEEIV
                     IGAPVSLPSMKAAMDKNSVPADIWGDNLMLHYVGKPQPGADSADENEPSFGYTLRRKG
                     MPVADKYDGAGGKVKYCRYTDIYKVAVVGGDAGYLITGISK"
     gene            48068..48406
                     /locus_tag="LSX49_001066"
     CDS             48068..48406
                     /locus_tag="LSX49_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HBL7167503.1"
                     /translation="MGTTQQVILITTVTAGAALAQQRFVGADNTPCKAGAAALGVAEV
                     DAVTGDSTPVSVLGIIAVEAGAAVSRGVAVQSDAQARAVPQSGDGKSCGIALDEAGGE
                     GDVIRILRGV"
     gene            48408..48854
                     /locus_tag="LSX49_001067"
     CDS             48408..48854
                     /locus_tag="LSX49_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1320 domain-containing protein"
                     /protein_id="HBL7167504.1"
                     /translation="MYCTLEDLLAQVPERTLIELTSEEMDFDSPATVNTRVVDSCIRY
                     ADELIDAHLRGRYILPLAEIPTVLRDIAITLVRYRLYARRPEGDLPDTVKDDHKEALR
                     QLRELRDNRLTLGLPSTQKDVPEPGEFRVRSRPATFGGRDGLLEKY"
     gene            48854..49318
                     /locus_tag="LSX49_001068"
     CDS             48854..49318
                     /locus_tag="LSX49_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gp37 family protein"
                     /protein_id="HBL7167505.1"
                     /translation="MNVLPVLDAVLARLREKLPQLQVEYFPEKPAEYRLNHPVGALLL
                     SYAGSRFDRPDDTGAVIQSQTIQLCVTVVFRQLNGKKGAINVLDAVRRILGGHTPPGC
                     RRRIWLTREVFIGEVRGLWQYALDFATESVFIEDSDLPSGPLLTEVNYEESE"
     gene            49318..49569
                     /locus_tag="LSX49_001069"
     CDS             49318..49569
                     /locus_tag="LSX49_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167506.1"
                     /translation="MKEYRYSGPASGVTLSDGTEILLWPGKTVSLPEEHDYVKVLVAL
                     KHLTPVPEETKPAGTPAVQSPKRRSSSDSEVKTEDTHGS"
     gene            49559..50986
                     /locus_tag="LSX49_001070"
     CDS             49559..50986
                     /locus_tag="LSX49_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001702162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBL7167507.1"
                     /translation="MAANYLHGPETIEVENGARPVKTVKSAVIGLIGTAPMGDVNTLV
                     QCLSEKDAAAFGSQFTGFTIPQALDAIYDHGAGTVLVINVLDPAKHKTAIEDEVVTFD
                     KSTGQARLAHPVVANVVVKNSEGSTTHTANTDYRVDAQAGVLTNLGKAIEAGGSVKVS
                     YEYADPSKVTAADIIGGVNSAGNRTGMKLLNDSFNLYGYFAKILIAPVFCTQKSVAVE
                     LIAMAEKLGAVTYIDAPVGTTFAQALAGRGPEGTINFNTSSDRVRLCYPHVKVYDPVT
                     NTERLEPLSQRAAGLRARVDLDKGYWWSSSNQEILGITGVERQLSAMIDDPQSEVNLL
                     NEQGITTVFSSYGSGLRLWGNRTAAWPTVTHMRNFENVRRTGDVINESIRYFSQQYID
                     MPITQALIDALTESVNAYGRKMTGDGAVLGFRCWFDPARNPETELAAGHLLLSYKYTP
                     PPPLERLTFETEITSEYLLTLKGGN"
     gene            50983..51507
                     /locus_tag="LSX49_001071"
     CDS             50983..51507
                     /locus_tag="LSX49_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HBL7167508.1"
                     /translation="MMSKIEINRITNANIYLDGTNLLGRAEEVKLPDVSMIMQEHKAL
                     GMVGKVELPAGFDKLEGEIKWNSFYRDAMLSAANPYRSLALQCRSSVQRYSSQGLIDE
                     IPLVTFLTIMFKKNPLGTFKQHENAEFSSSFTCTYIRQVLDGEELLQLDYLANIFRVG
                     GVDQLTDYRINIGG"
     gene            51510..51791
                     /locus_tag="LSX49_001072"
     CDS             51510..51791
                     /locus_tag="LSX49_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167509.1"
                     /translation="MSVELTDKGGRCAALGMSNGTWFTLLDIPGVETLFNTRKTNDPI
                     DCTRSKARKLADLIEAWEPPDHWFSGIGKSEGKTLLIAFLRNCKGFRTC"
     gene            51889..52224
                     /locus_tag="LSX49_001073"
     CDS             51889..52224
                     /locus_tag="LSX49_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HBL7167510.1"
                     /translation="MSQTPSDTFKLSYPFTTAAGTRIELVELKRLTVKDLKQVRKISK
                     NPADWDEPLIARSTGLLPEDLDNMDLADYLQLQKRFQLITGMGESNQGADAGAGAAGE
                     MVPVSAGGD"
     gene            52148..52306
                     /locus_tag="LSX49_001074"
     CDS             52148..52306
                     /locus_tag="LSX49_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HBL7167511.1"
                     /translation="MRATRALTQAQGLLARWFRFQPGEIDALDTDDLEMWLEQAEEQI
                     KSEYGDKS"
     gene            52382..55333
                     /locus_tag="LSX49_001075"
     CDS             52382..55333
                     /locus_tag="LSX49_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001705208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL7167512.1"
                     /translation="MSGQFSVGVVIGGMIGSTFRSAMSGTRRALDSLSDTSRRLQERQ
                     NALTRATERYGQLGSSRMQHLNSELLRVSRTMEQIERQQRRLSAASATSDALKANRMA
                     LYGQGIEAYGMAQTVYHTVSPAVQQSMSFQDKMIDMSITAKYDNKTRDALAGQIKGWA
                     LKYNQYQDELQEAMGSLISDNIDNVSDIGFLMPDIARAATATRTSAQDWAKVAAVWQN
                     SLKGAARDFGAVQNIMAYAGDQGSFEIPDQVKWMQSLAPMMAGIASGKEAVAEIGASL
                     QIAKIGAGSTDEAANNFKNFLTKIFARDTQKQFADLGIDLQGSIASYKAAGISPIEGM
                     LSVIERYLNAKSPEALAGFKSAMKIKNDTARDEALQALAKNFGLGDMFADMQVMAFIR
                     PMLANMDRYREIRAGALRAADNDLLASAYDQRLKSPLEATKTLMVSSRDLAITLGDQL
                     APSFISLTQDLLPLIQGTKHWVATHPQFVSGAFKLISALLAIKIATVGLKLGLNLLIS
                     PFVNVWKTAVLLRTNWHRLTTALGEGGKLRWLVTGFSRLTSGGLKLSKVLAGSLVRGF
                     MSAARAVLWIGRALMMNPIGLVITAVAAAAYLIYRNWGAVSGWFKQRWADIQEAFNGG
                     IAGTGKLLINWSPAGLLYKAFAAALKYFGVTLPAKFTDFGGHLIDGLINGIKNKWGSL
                     KSSVTGMGDSISSWFKQCWADIQEAFNGGIAGTGKLLINWSPAGLLYKAFAAALKYLG
                     VDLPAKFTDFGGHLVDGLINGIKNKWESLKSSVTGMGDSISGWFSEKLGIHSPSRVFM
                     GFGDNIAQGAAIGLQRTTPLAALAGQRMASELLPRMPVSIQGPEIRDNTSGVRFSMPL
                     PDINGFMSSAKNAIGAVINSLSSMPAIPLSTRASILPGQRLANEMTPDVPRIPSPEIL
                     AAGYSGRGAAATGGGTSGGIQVSFNPQFFLNGRETTAPAGLTGALNMSLHELEKMLER
                     LLAQKQRKEYR"
     gene            55333..56217
                     /locus_tag="LSX49_001076"
     CDS             55333..56217
                     /locus_tag="LSX49_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001423226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7167513.1"
                     /translation="MFAVLGDIEFELITYWDGFEATFGVDYAEHARIGGKPGLQFVGD
                     RLDEIQITLVFHQHYCVPDVELARLRTAMKAHQALALVFGNGDYRGWFVITDVTATSE
                     QTDSTGNVLAVSATVSLREYTGDPKNPLQPPAIRTKLPGVGAVSGAIPSPSGVAQFIR
                     NGVNYAKQAQSVLQTTISAVRVTQKMKDNPVVALTRVPGLMSGLGNISGALGKSVPAF
                     NALSESMPDAISLARTASEAATYVQQAQSALSGVDKRNIAGALDTVSGQLNAVGTAFN
                     RMSPGLSAMAARILTRSV"
     gene            56217..56429
                     /locus_tag="LSX49_001077"
     CDS             56217..56429
                     /locus_tag="LSX49_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HBL7167514.1"
                     /translation="MFLEHVTRDGERWDSLAWQYYGDPLGYPRIIAANPHVAITPVLP
                     SGLLLLIPVIEAEEARTEEDIAPWLR"
     gene            56417..57571
                     /locus_tag="LSX49_001078"
     CDS             56417..57571
                     /locus_tag="LSX49_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HBL7167515.1"
                     /translation="MAEINSTAQVTSALTGVSDVLTPVFTLWYLQKNITSDIAPYVTR
                     VTWSDNIKNESDTIEVELDDTDGRWLDKWYPGKGDTLTLKMGYQGEKLLSCGTFSIDE
                     IEVSSPASVVSIRGVATSVNSALRTKTSRGFENTTLAAVAGRIARKHRLKLVGSIESI
                     RIDRVTQYAETDVGFLRRLASEYGYAVKVVSDQLIFSHLATLRSQEPVRQLKPQDVAR
                     FSLRDTINRVYKSAKVKHQKSSSKKLIVYEADGGTRESDKKLKGGKVTSADSLKVNSR
                     VSDPDSARIKADSALARHNEYQQNGSLTLTGTPQLTAGNKIELVSFGQLSGPWLITTA
                     RHAFDRNSGYTTELEVARGPVTRGKKQKTQKLTVYHPDGSTSTVIKEKKK"
     gene            57568..58164
                     /locus_tag="LSX49_001079"
     CDS             57568..58164
                     /locus_tag="LSX49_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HBL7167516.1"
                     /translation="MTGVTRQVGTVSAVDADRVQARVRLPECDNLRTNWLNVLQRNTQ
                     DNKDYWLPDVGEQVEVLLDANGEDGVILGAVYSDVDKPPFSDKNIRGTRFADGAEYSY
                     NRKTHTLIIRGGIEHIVIECGADVVLKTQKATIDAPETELTGDLRVRGKLIYEGGMAG
                     SGGEGVTATIHGNIEIKGNVHATGSMLSDGENSSHHSH"
     gene            58219..58566
                     /locus_tag="LSX49_001080"
     CDS             58219..58566
                     /locus_tag="LSX49_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HBL7167517.1"
                     /translation="MKTTSVFWQPALQAPGEIVRGLDDIRQEIQIILRTPRGSDPHRP
                     EFGSNLHLYIDWPVDRAIPHVVRESVDAIRRWEPRCQLMSVKPAVDGEHLTLRVSWKG
                     SDGQTRTQELLWR"
     gene            58557..59660
                     /locus_tag="LSX49_001081"
     CDS             58557..59660
                     /locus_tag="LSX49_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012905229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBL7167518.1"
                     /translation="MALTEPDFIERDADKITAEMIAKYEADTGKTLYPAQAERLLIDL
                     WAYREMLVRVAVQEAAKQNLVAFAREPMIDYLGELVGVYRLAAQPATTTLQFSVDEAL
                     AIDVLIPAGTRVSASDSVIFATDTDVVLKAGLLLVNVTATCTEPGTAGNGWQPAQVSQ
                     LLDEIDNVNLLVSNLMASSGGSEQEDDDRLRERIRLAPESFTNAGSRGAYRFHAMQAH
                     PNIVDVAVLSPVPGTVDLYPLLSTGLPDGGVLTLVESFCSDEKVRPLTDTVRAKTPVK
                     VDYTIEARITIYRDQDARSVKDAANSAIQNWVASRAATLGRDIVPSQIISALSVSGVY
                     QVELVTPALRVVAENEWANCTAITLNMTGVSDD"
     gene            59653..60231
                     /locus_tag="LSX49_001082"
     CDS             59653..60231
                     /locus_tag="LSX49_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HBL7167519.1"
                     /translation="MTEPLQLPPPLEGDISLRTLGRLAGRLDNIDLSVLMVFLVDIVD
                     SSALPWLGEQFSLSGDGWELAESDDVRRMLIKAAIELHRYKGTPWSIREVIRRFGFGE
                     VDLIEGTGRLSYDGNRSYNGLFVHGDAAAWAVYRVILKQPITNDQAAMLRQTLAAFAP
                     ARCHLASLEYQSVAIRYNNTAIHDGSYNHGSS"
     gene            60234..61481
                     /locus_tag="LSX49_001083"
     CDS             60234..61481
                     /locus_tag="LSX49_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HBL7167520.1"
                     /translation="MGNLNETEKWEENIYQLETSDPVLGGADGISNRAPRQLANRTKW
                     LKKKTEEAAQSLAEHVRSRNHPDATLTAKGFTQLSSATNSTSETLAATPKAVKAAYDL
                     AAGKAPASHTHPWSQITGVPAASLTAKGTVQLSSATDSQSETEAATPKAVKAAYDLAA
                     GKAPVSHTHPWSQITGVPAASLTAKGTVQLSSAINSTSEILAATPKAVKAAYDLANGK
                     QPADATLTALAGLATAADRLPYFTGADRAELATLTAIGRAIIAKGSIKDVLNYLGLGE
                     GSALPVGVPVPWPTATPPAGWLKCDGRAFTKEQYPVLARVYPTLRLPDLRGEFIRGWD
                     DGRKVDTGRDLLSRQDGTSFSHYAGNFDIGSGHSINNYDQIVDNQPGFSRFSFAGPSR
                     GDGVNYVTIRPRNIAFNYIVRAA"
     gene            61492..61953
                     /locus_tag="LSX49_001084"
     CDS             61492..61953
                     /locus_tag="LSX49_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001491734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HBL7167521.1"
                     /translation="MGEGSALPVGVPVPWPTATPPAGWLQCNGATFTKEQYPVLVRVY
                     PTLRLPDLRGEFIRGWDGGRKVDTGRALLSFQEGTIVSGFDDNDTGDISSLGSTQYGF
                     GDALTSNQLGVLNGKKWIFDASSKGAQRYDWWAYVSARPRNIAFNYIVRAA"
     gene            complement(61960..62574)
                     /locus_tag="LSX49_001085"
     CDS             complement(61960..62574)
                     /locus_tag="LSX49_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBL7167522.1"
                     /translation="MSNTAVLDENGIATVAGDITVYHYDEETREYTSSSVEYLALGVG
                     TPAHSCADAPPEAISGYVVCRTATLNGWEHVPDHRGETVYSTENGNPVLITQPGDYPA
                     DTTTKQPATPWDTWNGEAWVTDTERQRAAELEVARQQRQQRVKQAMASVDLINLKLRA
                     GRSLKPEETAKLNAVLDYIDELNALDISKAPEISWPEAPLALAG"
     gene            complement(62574..63098)
                     /locus_tag="LSX49_001086"
     CDS             complement(62574..63098)
                     /locus_tag="LSX49_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HBL7167523.1"
                     /translation="MNVGLGEGSALPVGVPVPWPTATPPAGWLKCDGRAFTKEQYPVL
                     ARVYPTLRLPDLRGEFIRGWDDGRKVDTGRKLLSAQGATLLRTAMLDYYNQDTTGTSG
                     IVGMGFNNEDSITDLREGSFKMPDGTTFSDPVVAMSDNGMQATILTSIRSGYAKGITV
                     RPRSIALNYIVRAV"
     gene            63158..>63293
                     /locus_tag="LSX49_001087"
     CDS             63158..>63293
                     /locus_tag="LSX49_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL7167524.1"
                     /translation="MLIGYIRVSTNDQNTDLQRNALMCAGCEQIFEDKMSGTKSERPG
                     L"
BASE COUNT        14495 a        17055 c        16803 g        14940 t
ORIGIN      
        1 ttccttaatt tttacttttt gtcacacatt ttttcttttt gaaaccaaat ctttatcttt
       61 gtagcacttt cacggtagcg aaacgttagt ttgaatggaa agatgcctgc agacacataa
      121 agacaccaaa ctctcatcaa tagttccgta aatttttatt gacagaactt attgacggca
      181 gtggcaggtg tcataaaaaa aaccatgagg gtaataaata atgatgaagc gcaatattct
      241 ggcagtgatc gtccctgctc tgttagtagc aggtactgca aacgctgcag aaatctataa
      301 caaagatggc aacaaagtag atctgtacgg taaagctgtc ggtctgcatt atttctccaa
      361 gggtaacggt gaagacagtt acggtggcaa tggcgacatg acctatgccc gtcttggttt
      421 taaaggggaa actcaaatca attccgatct gaccggttat ggtcagtggg aatataactt
      481 ccagggtaac aactctgaag gcgctgacgc tcaaactggt aacaaaacgc gtctggcatt
      541 cgcgggtctt aaatacgctg acgttggttc tttcgattac ggccgtaact acggtgtggt
      601 ttatgatgca ctgggttaca ccgatatgct gccagaattt ggtggtgata ctgcatacag
      661 cgatgacttc ttcgttggtc gtgttggcgg cgttgctacc tatcgtaact ccaacttctt
      721 tggtctggtt gatggtctga actttgctgt tcagtacctg ggtaaaaacg agcgtgacac
      781 tgcacgccgc tctaacggcg acggtgttgg cggttctatc agctacgaat acgaaggctt
      841 tggtatcgtt ggtgcttatg gtgccgctga ccgtaccaac ctgcaggaag agtctcccct
      901 tggcaaaggc aaaaaagctg aacagtgggc tactggtctg aagtatgacg cgaacaacat
      961 ctacctggca gcgaactacg gtgaaacccg taacgctacg ccgatcacta acaaatttac
     1021 aaacaccagc ggcttcgcca acaaaacgca agacgttctg ttagttgcgc aataccagtt
     1081 cgatttcggt ctgcgtccgt ccatcgctta cactaaatct aaagcgaaag acgtagacgg
     1141 tatcggtgat gttgatctgg tgaactactt tgaagtgggc gcaacctact acttcaacaa
     1201 aaacatgtcc acctatgttg actacatcat caaccagatc gattctgaca acaagttggg
     1261 cgtaggttcc gacgataccg ttgctgtggg tatcgtttac cagttctaat agcacacctc
     1321 tttgttaaat gccgaaaaaa caggactttg gtcctgtttt ttttatgcct tccagagcaa
     1381 tctcacgtct tgcaaaaaca gcctgcgttt tcatcagtaa tagttggaat tttgtaaatc
     1441 tcccgttacc ctgatagcgg acttcccttc tgtaaccata atggaacctc gtcatgtttg
     1501 agaacattac cgccgctcct gccgacccga ttctgggcct ggccgatctg tttcgtgccg
     1561 atgaacgtcc cggcaaaatt aacctcggga ttggtgtcta taaagatgag acgggtaaaa
     1621 ccccggtact gaccagcgtg aaaaaggctg aacagtatct gctcgaaaat gaaaccacca
     1681 aaaattacct cggcattgac ggcatccctg aatttggtcg ctgcactcag gaactgctgt
     1741 ttggtaaagg tagcgccctg atcaatgaca aacgtgctcg cacggcacag actccgggtg
     1801 gcactggcgc actacgcgtg gctgccgatt tcctggcaaa aaataccagc gttaagcgtg
     1861 tgtgggtgag caacccaagc tggccgaacc ataagagcgt ctttaactct gcaggtctgg
     1921 aagttcgtga atacgcttat tatgatgcgg aaaatcacac tcttgacttc gatgcactga
     1981 ttaacagcct gaacgaagcc caggctggcg acgtagtgct gttccatggc tgctgccata
     2041 acccaaccgg catcgaccct acgctggaac aatggcagac actggcacaa ctctccgttg
     2101 agaaaggctg gttaccgctg tttgacttcg cttaccaggg ttttgctcgg ggtctggaag
     2161 aagatgctga aggactgcgc gctttcgcgg ctctgcataa ggagctgatt gttgccagtt
     2221 cctactctaa aaactttggc ctgtacaacg agcgtgttgg cgcttgtact ctggttgctg
     2281 ctgacagtga aactgttgaa cgtgcattca gccaaatgaa agcggcgatt cgtgctaact
     2341 actctaaccc accagcacac ggcgcttctg ttgttgccac catcctgagc aacgatgcgt
     2401 tacgtgcgat ttgggaacaa gaactgactg atatgcgcca gcgtattcag cgtatgcgtc
     2461 agttgttcgt caatacgctg caggaaaaag gcgcaaatcg cgacttcagc tttatcatca
     2521 aacagaacgg catgttctcc ttcagtggcc tgacaaaaga acaagtgctg cgtctgcgcg
     2581 aagagtttgg cgtatatgct gttgcttctg gtcgcgtaaa cgtggccggg atgacaccag
     2641 ataacatggc accgctgtgc gaagcgattg tggcagtgct gtaagcgtta aaaccgatga
     2701 agcccgcttg aaagcgggct tttttatgcg cctttaccag acaggcattt cgtcttgcaa
     2761 gaagggatta tgcaggcgct cataaccgag agtggataat ggtccgtgac ccggaataaa
     2821 tgtcacgtca tcccccagtg gcagcaattt atctttgatt gaagaaatca gttgattgtg
     2881 atcgccacgc gggaaatcac tgcgccctac tccgcctttg aaaataacat cgccagaaat
     2941 gagcagcctt gcctgctcat taaaaaacac cacatgaccc ggcgtatgcc cggggcaatg
     3001 taacacctgt aaagtcacat tccctatgct gatggtatcg ccttcgttca gccaacgatc
     3061 tggcgtcagc ggctggcact cttccagacc aaacatacga ctttgcgcag gcaagccttg
     3121 cagccagaac tcatcttctt tttccgggcc aaaaaccggc acgccgtaat gttgcgccag
     3181 ttccgccgct gcgccaacgt ggtccagatg accatgagtc agcaggatct gcatcagtgt
     3241 caggccgctg gcatcaactt cctgtttgat tttttccgca tcgccgccag gatcgaccag
     3301 tgcggccaga cgggtttgtt cacaccagat caatgaacag ttctgggaga atgcggtgac
     3361 cggaataata cgatagttca tactgcccct gtttcgttaa gcgattacta ccagtgccgt
     3421 gctggcccgg tatcaatatg cacaaagtta ctacgtgggt aatatcctac accacctgcg
     3481 cgcatagata acgcggcttt gcgaatattg cttaacgcga taccttcaat gtggaaatcc
     3541 atcgcctggc ctttggtgtg atagcttttc ttcgctactc cacggctgcg ggcgcgtagt
     3601 tcattgttgg tatcaatgga acgataaccg gaaatgagtt gcaccggttt gcgggtgcct
     3661 aacaaccctt gcaggcgata caactggtcg aataatcctg ggtcgatgga ctttattttg
     3721 ttcgcgcggt aatcgcggaa aaaatggtta agttttgcca attcttcctg aatatagcct
     3781 ctgccatcga aaaactccgc tttgattgac tctccggtat gaagattatt gagtgtcaaa
     3841 atgcgcgggc gtggggtaga gagtgttgca aacgccgggg tcggcaggat ggcggcaccg
     3901 agtgcaacgc caccaagcgc cagcagtttg cggcgattag cgtcgaattt gtccatgata
     3961 atcaagtcta caggtcaatg ttatcgttta tatgcacttc tggcgcacaa gaggcacctt
     4021 aaccgcccgt aaagaagacg tcaagatgac tcaaccccag cagtgacggg ggctgcagag
     4081 aatcgccccc gatcatgcta attattacga caactgattt ccccgaactg cttcatttac
     4141 ctgattaatt gttccgcttt cgatacaatt tgcgagctgg atcgcgcagg cagatcataa
     4201 ttgtaaatat ctgtacgata ctgggtacga ccatcagcac caacaaaggc cgtcagatag
     4261 tagagattca ccggaatcga ctgccgaata ttgacgtaac gcgtatcgcc ctgcttcagc
     4321 gcatcagaaa tacgtttgtc attccatcct gcatcctgca acagcatatt cgccagatcg
     4381 gaagctttat tcactcgtac acagcctgag ctcaatgcgc gtgtatcacg tttgaacaga
     4441 ttgtggttcg gcgtgtcatg caaataaatg gcctctgaac tcggcatatt gaatttatag
     4501 cgccccagcg agttccgtgg gcctggagcc tgctggaaac ggaacggtaa attcgaggcc
     4561 gtgattgtag accagtcaac ctgccatggg tcaatcgctt ctctgctgtt ccagccgcgc
     4621 atcaccgtat agccatggct ttcgagatat cccggatcgt tgcgcacttt cggcagaata
     4681 tctttgcgtg ccagagttgg tggtacgttc cacggcgggt ttaccactac gttgttaagt
     4741 gcactgctca tcatcggcgt tttgcgatcg gggcgaccga caatgactcg cgaatccagc
     4801 acctgattgc cgttctgata gtagaccagc gaataggctg gaatgttaac catgatcccg
     4861 gtagaaagct ctgttggcag caagcgcaat cgctggatgt tgagtgccaa cacgccagca
     4921 cgctgggcgg gcgttacgtt taaccagtca cgcgttgccg ggccaatagc accatctgct
     4981 cccaatcctt gccatgcctg aaaacgttta acggcttcca ccagttcatt atcgtaggcg
     5041 gcgcgaacgg caggcgcagg tttactacga gacgtagttt gtttgtccat cagcttagtt
     5101 tctgctgttt caacagtaac agccgatggg ctgactaccg cgtcagttgg cgtgtcatcg
     5161 ccaggtagcg taattttcgg tcccccgtcc aacatgcctg tacgttgcaa tatttcgcgc
     5221 aacgccggta cgtcgttact ccactgtcct gggcgcaacg ttgctttacc ggtcagttga
     5281 ggccacggtt tggtgtcact gagtaaggcc agtaacgatt catgcatcgc cgcatattgc
     5341 ggatgctgcg gtgccagtcc tgcaacaaac gtcggcaatt gacctttatc cagcgccagc
     5401 tgccattggt taatcaccga aagcggcggc gttgcaagcg cataaggttt actgctatat
     5461 agccagcgag tgcctttgac cggaatattt gcaatgaaat ggagatagcc catcatcgca
     5521 tcagagagca ccacgtcgcg tgccatcccg ttaacaccag gatcggtcag taactctacc
     5581 catttattaa actgcggctg gaaaccggca atcgccacct ctgccagctg ttgctggaag
     5641 gctttaacag catcacggtt ttcccacatg ggttgcatat cgcgtgcggc atacaacaat
     5701 tgaagctggt taagataaac cggcttataa cctgcgggta attgagattc gatttgcgtg
     5761 cgggcttttt cagccgcacc ttcaggcaat ggctggatcc ccgccattat tgccgtggct
     5821 tgcgcctgcg gcagtgcctc gccctgttca ctgacagcca ccgggctgtc gccagggatt
     5881 acttcaggct catcggcctg cgcattgaac agtggagcga atgttacggc caggcacaaa
     5941 ctgattgccg acagccgacg accacacatc atattaagca acatcccttg ccccctgttt
     6001 ttatcatact ctgaatagcc aggctgttat tttacgactt gcctgtacaa cgccaatact
     6061 cacgaaagta tgacgagcaa gcctgttact catcaggctt atcttcagta tataaacgcc
     6121 gatacgtttt tacataacct aatgtaaaga agtttaaaga aaagcgcgcc gtaatgtgcc
     6181 acttttttag tgcagaaacg gagttttcgg aaaaagaaaa ggcggcattg ctgccgcctt
     6241 aattttaact cgcctgagaa ggcgcttcgt cacttcctgg aagcgtttca gggagttgag
     6301 gcgcaaatcc tcgcaggccg acgacgtgaa cgtgttcggt attctggaag actttacgta
     6361 ccagtttata ggtggtgcct ttctccgggc tgatattttc cggcgctgcg ataatgagct
     6421 gcatttgcaa acgttcacac aattcaaaca gcgtggcgat ggaacgggcg tccagtcgcg
     6481 ctgcttcatc gaggaacagc aggcggcaag gagagatatc tttaccgcgc aggcggcgag
     6541 attcatcttc ccagctttgt accaccatca ccagaatcga cataccggta ccaatcgcct
     6601 caccggtcga caatgcacca gactctgcac gcaaccagcc atcggaacca cggttaacct
     6661 caacttccat ttccagatag ttgcggtaat ccagcagttc ttcaccgatg gtctgcggcg
     6721 tgcgctgccc catatcaatc tgcgggttaa gacgttgata cagtttcgcc agcgcttctg
     6781 agaaggtcag gcggttgctg ttaaacagat cctgatgctg ctcgtgctgt tcagagagca
     6841 catccagcag catggcgtgc gtttcacgta cgttcacgtt cagacgtacg ctgttcacct
     6901 ggccaaacga tacgttctgc aacccctggt tgagcatacg gatacggttc tgctcgcgct
     6961 gaatggtttt gcgaatgatg ttcgccacgc tgcgggaact gatcgccagt ttctgttcac
     7021 gagaggttaa ttcttcggtc agacggctaa gctcgatctc catctgttcg atagcttcca
     7081 ccggatcatc ggtacgaata atatcctgac gaatacgttc acgcagatgc tgataaaccg
     7141 ccacgaagaa ctgaatttta cgttccggac gttttggatc ttccgacatc cgcagcacgt
     7201 cgcgcagatg ttcgttatcc gccaccgcca gacgcagcgc acctaacgcc ttatccgaca
     7261 tggagcgcaa atcatcagcg gagagataag ccagctcacg acggtgtaag cgacgctcaa
     7321 cgccattatc tttcaccatg cgcatcaccg cacaccagcc cgctttggcg gtcactacct
     7381 gctcgcgcat ctcaaagtaa tcccgctcca gcttgcgcag tttacgggtc aggttgtcca
     7441 tctccgcttc gcagaaggta agcgcttttt ccagttgatt gcgtcgtgaa cggttattgc
     7501 tcagttgcgc gtgcaactcg tcacggcgaa tacgtgcccg ctcttctgcc ccgctatcag
     7561 cacgcacgcc gatatcctgc aattcacgtt gcagatcgtt aagtagctct tttttggtgt
     7621 catacgaact tttcagcgaa gccagcacct ggttgtactg attcaactgc gctgcgtgtc
     7681 cgcgcaacgc ttcacgagcg cgggtacgct ccgcttccgc ctgttccaga cgttcacgca
     7741 gtttttcgtt gagatcgctg ttaccgctaa gcatttctgc cgagtcagag tagctaaagt
     7801 gcgcacgacg ctgcaccact tccgtcaggg caaacgcctg ctgacgggca tcgcgctgca
     7861 tctgctgaga gtacgcgtaa tcttctttta attgttcgaa ctgttccggg tcgctctgca
     7921 ataccgaaac gatcggctcc agtttcgcca gttgattgcc aaactgctga acaaaacgcg
     7981 cggcttcctg ggcttcatcc agacgttcgc ggatttcatc gacgcgatcc gccaggctgt
     8041 catcagccaa caggttgaga cgcggcagaa tgcggttcag cgccgtaacg ccctctttcg
     8101 cctgctcaaa ctgaatacgc tgctgctggt tatcattttc atgattactc aacgcccgtt
     8161 ccagttcgac gcgacggctg ttcagttgac ggatttctgc ttccgggtca gactcaaacg
     8221 ccaccgccag atgactgccg ataaagcggc tgaacgcctg atgcagacgc tgggttttct
     8281 gtacatcaaa ggaaagcgtg gcgaagcgtt cggaaagcac ttcccgctcg gcatggaggc
     8341 tttcaatacg gctttcacgc gcagcacgac caaacagcgg cacttccggg aaacgtgaat
     8401 aacgccactg acgatcggcg attttcacca ccaccgcttt ttccagctca tcaacgctga
     8461 acacgctgtc atcgaatgac tgcggatccc cttcgatcaa atagagatct tccgggcaat
     8521 cggtcaagcc ttccaggtgt tcggttacct gtgacagatc tggcaccacg atggcgtggc
     8581 gtgacgggcc atacagtgct gagaagtacg gcgcatcttc caggctaacg tcgtcataaa
     8641 tttctgacag cagcacacca ccaaaacgct ccgccagcgc gttcagacgc tgatcttcag
     8701 aaccacctgg ctggcttaaa cgttcgatct cttcatcgac ggcgtttttg cgcgcgccta
     8761 cttcatcgcg ttcaacaatt gcctcgcgct cacgctccag caactgttgc agaaattcgg
     8821 tgacatcctg gctggaggtg aactcttcgc cgcactgttc gctcaactgg ttgagactgt
     8881 tttgcgctgc cagccaaacc ggcgcacgct gcatcaaact ctgaatgcga gactgcagct
     8941 gttcctgctc ctggcgcagt gccatccgct cttctcgggc gttagagacg ctatcggaaa
     9001 gagaggcaat gcgtgcttcc agctcctgat gcagagcttc cagttcatca atatcaaaat
     9061 tcttgccctg acgtttgcag aaatctgcca gcagacgctc agcttcttgc tgctcacgca
     9121 gacgctgttc cagttcgctt aagcgcatcc gcaacggctg aacctgctct gccaggtgac
     9181 gctgatcgac cccttcgcgc aatagttcgc gagcgacatc ccacgcctcg ttacgcgcca
     9241 gcgggccgtt gattgccacc accagctgat aagcctgctc aaactggctg tgcgcggttt
     9301 gcgccatgct cattttctgc tcaagagaga gcattttttc ggtcgcttcc agctctttcg
     9361 cctggaaggt ttccagccat tcggcagcgc tgtcggcggt taagtccggc agatggcaca
     9421 gttctttggc acgattaagc gcagcaatcg cctggttata ctggatcgcg cgcgtttgct
     9481 ggacgtccag cgcctgctgg tagtcagcaa gctggctttt cagctcgtcc acttccagtt
     9541 cggcagcttc cgcacgagcc tcgttctctt cctggcgttc gatggcttct gccaccactt
     9601 cgttttgctc ttccagacgg atctgcagct catcgagatc cgcttcgtag cgttcgatct
     9661 tctcctgctg acgcagtgcg gtttgcacca ggttcaggtg atcgctggcc gcctgataat
     9721 ccgcttccag atcgccttcg gcaccgttgt gctcagccag ctctcgcgcc atgtcgacgt
     9781 gtttgtactg ctcagccgcc agttgctgac gcgaagtatg tagctcgcga cgaaactcca
     9841 gggccttatc gagatgaaca cggcgctcgt tggcgtgacg catgtagtcc gccgccacgt
     9901 agttggtggc ttcgctgatc agatgcttaa acaggtcacg gtccgactgg gtgacacgaa
     9961 tcgcttccag cgtcatgcgg ttttcacgca gcgccgcttc catgtcctgg aacgctttcc
    10021 acaccccact gttttccggc aacaggtagt cgcgcagaga acgagtaatg gcgctggaga
    10081 tcccgccata cagcgaggct tcgatcagac gatagaattt actacggtca gacgctgagc
    10141 gcagacgacg cgcgatgatg cccagatcga acatcagcga gtggtaatcg gtaatggagt
    10201 tgaactgttt aaactgcacg ccttccatcg cctcgagctt gtctttcagc tcgttaagcg
    10261 gcagcacgcg cgcctggcgt tcgttcagag tttcggtcac cagttgtgtc ggctgcaccg
    10321 acatcggcag tccctgaatg gcaaacggct tgatatccac tttacgatcg cgtccggcaa
    10381 cctgttgcag acgcacaccg accaccacgc gctggtgacg cgagttaatg gtgtcgagca
    10441 tcgaataaca gacacccgct ttcagcttac cgtgcagacc tttatcgcgc gaaccgctgg
    10501 tggccccggc ttccgtagtg ttacggaaat gcagcagggt cagatcgggg ataagcgccg
    10561 taacgaacgc cgccatggtg gtggatttac ccgccccgtt accgccagaa agcgtcgtga
    10621 ccagctcgtc aaggtcaaaa gttcgggcaa aaaagccgtt ccagttaatc agcgtcagtg
    10681 agcgaaattt accgcgttca atcattattc ttcctctccg ctatctggct gactctcttc
    10741 ggtttcatcg ttgagttgca gatgattttc aatcggcatt gcttcaccat cacgaatcag
    10801 gcgacgctgt gcttcacggg gatcgtcgcc agcacgcaca tcggcgccga agcggaacac
    10861 cgattcggta atgcggaact tgctgctgtc gtggcccata aaccacacca tgcctaaacg
    10921 acgcagacgg ttgagcgaag aacgtacttt ttcctgcaac ttctgacggt caacgtctga
    10981 accggttgaa cggttgttca ccagtttcag cagtttcgct tcatcggcca gggtgagcag
    11041 ttcgtcgtac agttcctgtt gagtaaaaat cccctcattc gccagccgtt ccgggctgag
    11101 atagagataa cagaggattt tcccgaccat catatccagt tccgacaaga cggaacgagg
    11161 gatcagcgtg gtggaacgtg ggcgtagata gaagaaccct tccggtgcac gaataagctc
    11221 aacgttataa cgcgcgtaaa actcttccag atattcctga aaatccatca ggaatgcatg
    11281 attatccagt tcgtcgaggc caatatggcg gcctgaacgt aaggcgctat ccagcgccgg
    11341 aaataacgga ttcgccagcg cctgcgccag cttaaccggc atcacttgtt caatatttgt
    11401 cgatgacatg cgcctgtacc ttggctccgt aatcattaat cggctgccat ttcgctggca
    11461 gtccggtgaa atctgcttgc gctacgccaa gacgtaccgc ctgatcaata acaatgcgcg
    11521 caacgtcaaa gtgacgtgca cgcggatact gtgacagata ttcgcgtacc accagaccaa
    11581 gatccaacgg cacttgtctg gttttgtaca cggcaagttg ttcttcgatg atcgccgcca
    11641 gctgttcgcg gatctcgtta aactcttcgt actccagatc ctcaggaagt tccccagtca
    11701 cttcttcatc gcgcagtacc atctcttcgt cacgcatatc cagcagacga tcggcattgg
    11761 cataagttag cgcccacggc tcatcaaaat aggtttgtac cgactgacgt aaccgctgag
    11821 caaagacgcg gtttttatcc atatcgatcg cagtacgaat aaatttgtgt acgtggcggt
    11881 cgtagccaat ccacaagtcg atggattgct ggccccaact gataatacgg tcgagtttgc
    11941 tctgaagatc gaacaccaga cgatcgacaa aatgcaggtc gtcatgggtc atcgtcgcat
    12001 cctgaatgcg taacaggttg gcctgcaatt tatcgcctgc cgcttccagc gtatcctgca
    12061 attcacgcag cgttccggaa gtttctgaaa gcaacaattc acagctggaa atcgccgccc
    12121 gccagtcttt gttcaacaac tgggcgatat catccttcac ctgctgctgc tgttcatcca
    12181 tcagacgttg cgtcaggtcg atactgtcga aaatttctgc taccgaatat ttcagtggcg
    12241 cataaacatt gcggtgccag tgaaattcat caccgccctc ttcggcggca tctgctgcgc
    12301 gtttgagctc acccgccaca atcgacaatt gcatagaaag gcgcagcgta gaaaactcgc
    12361 gctgacgaat gtaatagtca gtgatgccga tgccgagcgg cgtcagacgg taaattgcgt
    12421 tcccttccgc ctgctcgctg gtaaagcggt tcagcagacg ttgacgcacc atgtcgttga
    12481 tcgcgttgtt ggcgcgcacg ccgatggttt cgctggtttg ctcaaacgca tcactcacat
    12541 ggcggaatgc atccaccagc tcgccttcac tcatctcacc atccagacgc tcgccgttca
    12601 gcgtggcaac cgccagcaga aaagagagtc ggtctaccgg cagcgagatg gagaagtcat
    12661 tttttctggc ccaggcaacc agttcgggga ctgtctggga aaattcactc atactttatc
    12721 cttgctctgc ggtttgcgcg cggtgacatg aatataacgc cccagggtaa tatacggttc
    12781 ctgacggcaa taacgcgttt ctaattcaag taatgcttca tagcagtcgc gctgctggtg
    12841 cttctcacgc agataatcat gaaacacgcg aacgcctgtc ttacccagaa tttgccaacc
    12901 agcttcttcc agccacagat aaacctgcgc cgggtcgcgt ggataatctg gcgaaagcgt
    12961 ccgttttttc tttttcggca ttcccgcctg cacgtaatca aaattcccgg cgaccatgtt
    13021 atgcatcaac aaaccatgcg cattgtagaa cattaacgac aacacgccgc ctggacgcaa
    13081 cactgaccac agggtctgta atacgctgcg gggatcggcc acccactcga gcaccgcatg
    13141 gaacaatatc agatcaacgg gcgtttccaa atgcgaagca acatcctgag cggcgcaatg
    13201 tataaattgc atgttgtcgc tcacaccttt tgcttctgcc gcctgttttg cgcggtcgat
    13261 catctgcgca gaaagatcgc ataaaatgac ctgatgcccg cgctcggcca ttttgattgc
    13321 ggtctgccct tctccaccgc cagcatccag cacacgcagt ttttgcgggc ctatttctgc
    13381 cagcacgcga tcgagatcct gccacagaat agcctgtcga agctgccctt tggtggtgcc
    13441 gtaaatgtta cgggaaaact tttccgcaat atcatcaaaa ttgcgatcct gcattgcttt
    13501 ctccaccggt tggctaagac gttttctgat aaagacgcta ttttgtcaca gccacggcga
    13561 gaatgaaccc gtctggtgta atatcgctgg cgatcccttg ctatatggtt aaaaaaggaa
    13621 ccagaaagga tgctttttac actgaaaaaa gtgattggca atatgttgct gccacttccg
    13681 ctaatgttgt tgattattgg cgctggcctg gcgctgctgt ggtttagccg ttttcaaaaa
    13741 accgggaaga tttttattag cattgggtgg ctggcgctct tgttattgag tttgcaaccg
    13801 gtagccgacc gcctgctgcg tcccatcgaa agcacctatc cgacatggaa taattcgcaa
    13861 aaagtggact atatcgtggt gctcggaggt ggttatacct ggaacccgca gtgggcgccg
    13921 agctctaatt taatcaataa cagtctgcca cgcctgaatg aaggtattcg cttatggcgc
    13981 gaaaatccgg gatcaaaact gatcttcacg ggaggcgtag ctaaaaccaa tacggtgagc
    14041 acagccgaag tcggtgccag agttgcgcaa tcgctgggcg tgccgcgcga gcaaattatc
    14101 accctggatt tgccaaaaga taccgaagaa gaagctgcag cagtgaaaca ggcgattggt
    14161 gacgcacctt tcctgctggt gacctccgca tcacatctgc cgcgggcgat gatctttttt
    14221 cagcaggaag ggttaaatcc gctaccagcc ccggcgaatc agttggccat cgactcgccg
    14281 cttaatccgt gggaacgggc aatcccttct ccggtttggt tgatgcatag cgaccgcgtt
    14341 ggctatgaaa cgcttggccg gatctggcag tggctgaaag gttcgtcagg cgagccacgg
    14401 caagagtgat tttgatgcca gatcgaagtt acgccgatta aatcgtccgg tgttgaccag
    14461 ttgcgcaact tcatcccata acacatacaa ccaacgccgc cagatgaacg actccgccac
    14521 tggcgcgcgt tgcagataac tccagagcaa atcttccgcc agagaattat ccattagtcg
    14581 gaacagttcg tattctcgcg gtgcccaaag cattagtccc ggtccgacca tcgccagtaa
    14641 ctgatcgctg cgcgaatctt tcagcatgct gcgtaaacag aagttaccgt gaatcagtac
    14701 acaattgtcg ttaaagcctt caaataatgc cgggagacat tcgcgagtgc gaaacaggat
    14761 ccgcttatcc tgcatcgata gaccggtgtt attgaactga ttgagcgtgg tccatagcac
    14821 ttcaacatgt tgccggtacc atgagggcca gaaattttcc tgagtattgt cgaccgcgcc
    14881 gacgcaacca cgactgtcct gacggtgcca ggccagtaag gcttcaacga tttggtcttt
    14941 gagttgttcc cagcgttctg gtgttcgggc tggtgcctcc accgaaacac cacgcattcg
    15001 ctccagtagc aggacatcgg ggccggggtg ttcttcatgc gtcatcacac cataaatagt
    15061 cggcatacgg acagtcccac ttcttgccag catggtggtt ttccatgcca gttgtcgggc
    15121 ttttccgggc gtactaaagc ttcttgccat taacggcatt gggtttccct ggctgtcata
    15181 caaagcccac aacgccgtat ccgctttttc attgacgcac tcaatacgac tgagtttttc
    15241 gcccagtaaa tggcttaatt cggcacgcag ctgttccatt cagattaccc tcataaaagc
    15301 tactgctttc ataatgagcg ccaatataaa agatgtcacc tgaatgagat caattgttga
    15361 aaagaaaaat tgaggaaaat cgtaacggta cgacactcct cccaaaattg gctggagtgt
    15421 cgtgaagtga aattagcgca tttcagcgcg aacgcgctcg agatcttcag gggtatccac
    15481 acctgtgcca ggaacttcct gggcgacagc aacgtggatt ttttcgccat accacagaac
    15541 acgaagctgc tctaacattt cgatatgttc taacggactt ggctgccagg taacataacg
    15601 acggataaag cctgctcggt agccataaat accaagatga cgcaggaagt tatcgccaac
    15661 ggtttcaagg tcttttgcaa aacgatcacg atcccacgga atggtggcgc gagagaagta
    15721 cagtgcgtac ccttcggcat cgagaaccac tttcaccgca ttcgggttaa acgcttcttc
    15781 cgcattgtgg attggcaccg ccagagtcgc catacccacc tgacgctgag cgaggttatc
    15841 agcaacctga cgaatgattg tcgcagggat catcggttca tcaccctgca cattaacgat
    15901 caccgtgtcg tcgctgaatg cgcatttttc gacaacttcc gccaaacgtt ctgtacctga
    15961 ctgatgatcg gcgcgcgtca tacatacttc gccgccagcg gcttcaacag cgcgggcaac
    16021 atcctcatga tcggttgcca cgatgatgcg ctcggcacct gattcgcgcg cgcgttcaag
    16081 aacatgaaca atcatgggtt tgccgttaat atcaaccaat ggtttaccgg gcagacgcgt
    16141 ggacgcgtaa cgcgcgggaa taatgaccac aaaactcatg atttaccctc atcagcagtc
    16201 agcacgcggg cttccgtttc cagcaacact ggaatgccat cgcgcagcgg gaaagccagg
    16261 ttgtccagtt tgcaaataag ctcttgtttt tcctggttat accaaagttt tccgttgcaa
    16321 accgggcagg caatgatttc aagcagacga tgatccatag ttcctccaga tggatcgggt
    16381 tatgaatgca taaatcttat cataatcatt tatgcgacgg ggtctatttc ccagccggcg
    16441 cggcaatcag taaagaggcc ttgcgagcag cgtcctaatg tcacccgcgt tgcctgctgc
    16501 cagttagcga aatcagtaat cgcctgacgt aacccttttt gcagcgttgt cgttggttta
    16561 atgccttcct gtaaccacag agagataact tcaaggatgc ctttctggcg atgcattttg
    16621 gaatccattc gcccaactaa ttgcccacga tgtaataacg gcagaacaaa atagccatac
    16681 tggcgtttcg gcgctggggt atagcactcc agccggtagc taaaatcaaa aagctgctcc
    16741 gcgcgtttgc gatcccagac aacaggatca aaaggcgaaa gtaccgcgct gtgcgttgca
    16801 gtgagctttc cggcgagcgc acgctcgagt agcggcagca aatcagcatg cagccaaaga
    16861 ttgcccaatt tttcaacatg cacagcaatg atttgctgct gttcagccct cgcttcacgc
    16921 cacgccgcca gtgccggacg ttttagccgg tagtaatctg ccagccactg ttcgcgaaat
    16981 attcccaggc tacgcgcact gttatccagc atgatgattt ctgcttctgc ttgcgaaacg
    17041 agatcgcgct catcatccca gtcaggcatg acacggtggg ttaaatcata aacgcgctgg
    17101 aagttgcgcc gttcaatcac catcaccttt ccggcagtaa ataaaccttc cagatgtcgt
    17161 ttatgcggct tccactccca ccagccgctt gcacctttac gaggatgctc aaaatcggct
    17221 gaacgtaccg gccccctatc atgaatatgc tgaattaaca gtgcaatttc cgccgcatgt
    17281 tcctgcatcc aggcgtcttt atatttccag cccatttttt caggtgccag catgcggtgg
    17341 cgaataagac gaaaatcgct acgcggcata aagcaggctt catgcgccca gtattccatt
    17401 aattcgccac gcgccagaga ctcatccagc cactgggcag gataatttcc cagacgactg
    17461 aaaagcacca gatatgggct acgggcaaca atattgatgg tatcgatttg cagcaaggac
    17521 atgcgggaga tcgttgccgg aatatcctcc aacgacgctc gacggtgggg tttgtttaac
    17581 aggccttgtg cagcgagatg aagattacgc gcatcagcaa gggagaggtg cggcagagac
    17641 attcatgact ccatcaatcg aacgctgccg cggcgtaact agttgccaga agccagcgaa
    17701 gttagttgcg caagcagttt cgctggttca tcacctgaaa gctgtgcgtc tacaggcaaa
    17761 taccaccaat tttcttctgc aaaggcccgg catttcaccg catctttttc agtcattacc
    17821 agcgtttgtc cggcgcttac caacgcgctg acatccgcat gattcaaaaa ctgatgatcg
    17881 gccagcggta cacatttttc gggttgtacg ccacacatct tcagcgtggc aaaaaagcgc
    17941 ggcggatgcc caatccccgc aatcgccacc acatgttcaa gctgagcaac gtcacaacgt
    18001 gtaccggtac gtaaattcac cgcctgaccc ggcagcagat gcatggggat ttcaccgctg
    18061 cgggggacac cgccgttgac gattaccgca tcaaccaact ttaagcgccc tgctcgctca
    18121 cgcattggcc ccgccggcaa ccaccagcca ttgccaaagc gacgcacacc atcaataacg
    18181 acaatttcca catcacgcgc cagacgataa tgctgtaaac catcgtcagt tacgatgatc
    18241 tgcacatcag ggtgttgcgc cagaatggct tttaccgcgt cagaacgcac gggagaaacc
    18301 gcaacaggcg cgccagtgcg ttgataaatc aacacaggct catcacccgc ctgtgctgtg
    18361 gtggtatctg ccgacaataa cagcggataa gattcagcct taccaccata tccccgcgat
    18421 acgaccccca cgcgaatacc gcgctgttgc agctgttcca ccagccagac aacgaccggg
    18481 gtttttccgt tgccgcctgc agtgagattt ccaaccacga caaccggtac gggggcacgc
    18541 caggcgcgct tcagttttag tttatagcaa agacggatcg cgccactcac caggccatac
    18601 aaccaggaga gtggcagcaa tagccgccat aaaggggact caccagacca gattttttcg
    18661 atcattggcc aaactgcatt ttgtgaagtt gcgcgtaaac gccacggtgc tcaagcaaat
    18721 cgttatgcgt accgcgttcc acaatgacac catcctcgac aaccacgatt tcgtctgcct
    18781 tttcaatggt agacaagcgg tgggcaatca ccagagaggt acggtttttc tgcaactcat
    18841 ccagtgctgc ctgaatcgca cgttcggatt cggtatccaa cgccgaggta gcttcgtcca
    18901 gaatcagtat cgggctatca cgcaacaagg ctcgagcgat agcaatacgc tgacgctgac
    18961 cgccagagag caacacgccg ttttcaccaa tgactgtatc gagaccgtta tccatcttat
    19021 tgatgaagtc catggcgtag gccatacgcg cagcttcttc aatttgctca cggctgtact
    19081 gttcagtcct tgcgtaagca atgttgttgg caaccgtatc gttaaacaga tggacattct
    19141 gcgacaccag agcaacctgg ttacgtaacg acgccagggt atactcgcgc agatcgtgac
    19201 catccatcag gatttcgcct tcatcaatat cgtaaaaacg tgtgattagg ctggcgatgg
    19261 ttgatttacc tgaaccagag cggccaacca gagcaaccgt cttccctgcc ggaattttca
    19321 ggttgatgtt acgcaatgca ggcacatcac gtcccggata agtaaaggtg acattgcgaa
    19381 actccacgtc gccagtcgca cgctcgatca cgcgcttacc ttcgtctttc tcctgctcac
    19441 tgtccagaat ggtaaacagc gtctgacaag ccgccatacc gcgctggaac tgggcgttaa
    19501 cgttggtcag cgatttcagc ggacgcataa gtgcaatcat tgaagagaaa acaacggtaa
    19561 tcgtaccggc agtcaggcta tccatgacac ttgggaagct tgccgcatac agaacaaacg
    19621 ccagcgccaa agaggcgatc agctgaatga tcggatcaga gatggaagag gctgaaacca
    19681 ttttcatccc ctgaagacgc attcggttgc tgactttatc gaagcgtttc gtttccactt
    19741 cctgaccacc gaaaatcaat acttctttat ggcctttcag catttgttcg gcgctggtgg
    19801 tcacctgccc catggtgttc tgcatgtttt tactgatgtt gcgaaaacgc ttcgatacaa
    19861 cgcgaatcgc aatcgaaaca atcggtgcca gcacaatcaa aatgatcgac agttgccaac
    19921 tgtaatagaa catcatgatg aacaggccga tgatcgacgc accttcacgc acaacagtaa
    19981 tcagtgcgcc ggaagaagaa gaagcgacct gttcggaatc gtaggtgata cgtgacaaca
    20041 gcgtacccgt tgactgtttg tcaaagaatg aaaccggcat tcccatcatg tgaccaaaca
    20101 ggcggcgacg catagtcatt accacctttc ctgataccca ggagatacag tagctggaga
    20161 tatagctggt gataccacgt aaaatcatca gcccgatcac caccagcggc atccacatca
    20221 gcacggagcg atctgtttta ccaaagccat catcaagaag tggcttaagg agcgataaca
    20281 tgaaggtatc gctggctgcg ttgaggatta acgctacgcc cgccacgatc agacccgctt
    20341 taaaaggcgc aatggttggc cacagtcggc ggaacgtctg ccacgtagag agatctttgt
    20401 cgttatgcat tcaaaaaacc agcatttgtt gaaatagccg catattctac ccgttatcca
    20461 ctggcacgcc aaaccactga tgataccaac gaggtaaaat ttgctctctg aggctgctaa
    20521 tccaccagcc ttgcgctgaa aaattgaccg ttatttgccc ctgatgtgga gtatcaagcc
    20581 acttataacc ctgttgatga tagcgatatt taactttgct tgagggcagt cgccatgcgt
    20641 tatagcgcga tgccgatgcg agtgccactt ttccattcac tcgctgaatt aatggcaacg
    20701 atgatgaggt attactgcca tggtgaggta cctgaagtaa tgttgcctgc atttgctgcc
    20761 agtaacggct tagcatcttt tgttcagcgg gggcttcaat atcaccggtt agaagaatgc
    20821 tattcgtccc gtcatcaatc ttaaccacac aggaatggtt atttccttta tcgttgctac
    20881 cttgtaaagg ccagtgcgcg ctgaaacgca atccttgcca ttgccacgct tcgccacgca
    20941 cacagggctg atgatgttcc cagtttaacg gacttcggat ccataacatc ggccatgtgt
    21001 gcaatattga gtccagccct ccccggtgat ccagatgttc atgactcaaa ataacgcctt
    21061 ccggttcaag attatgccag tggagccagg ggataatcag ttgttgccca ctatcccctt
    21121 cgggccaggc cagtcccgtg tcatagagaa tcgctttgcc gtttcgcgca atgaccattg
    21181 ccagcccctg cccgacatca agcatgtaca cttgccactc gtcaggtcga ggtttttgcc
    21241 acagcggcaa gcacatcagc aagcctacag ccacacacat tgctggcaac gttcgccagg
    21301 cgtttaatcg ccataccacc agtaagaacc atggggaaaa tgttagccat tgccaacgtt
    21361 cagcaatgtt gatccaccct tccggcaaac tctttaaccc ccagaaaagt aaagccaaag
    21421 accggtcggc aagaaaccat aacccttgtt ccagaataaa cggcccgctt aaatgcacaa
    21481 ccatcgcggc gagaatcaac ggaaccgtga taaatgtcac caggggaatt gcaaaaagat
    21541 ttgcaataaa cgaggtcaga ctaatgccat gaaatatgac aatttgcacg ggcataagca
    21601 ggagggtgat tcccagttgc agatggatga gggaaacaac cgcgcgcaat accggcggca
    21661 gctgccactc cggacaggga aaccactgat accaaaaaat cagtgccgcg accgcagcgg
    21721 cagaaagcca taaactttgc gagagaatgg caacaggatc catcagcaaa attgccgcca
    21781 gacaacatat ccatacatcc cagccactcc attgtcgtcc acttaactta agcattcccc
    21841 aaatggcaag cgccaccacg gtacgcaatg caggaggttg cattcccgta agccaggcat
    21901 aaaaagcagc acagcagatt ccaccaatta atggcatttg ccagtggagc cagcacccag
    21961 gcagaaaaac ttgcccaccg cgaatgagtc ctgcagccag caacgccgca aaagcgatgt
    22021 gcaatcctga tatcgccatt aaatgcgccg ttccagtatc acgcatgata tttttgattt
    22081 ctttggggac ggataaccgt tcccccatac ctaatccaag aataaccgcg ttccacatat
    22141 agggttgcag cgttgtttgt agtgacgcca gatactgtgc acgcaggcta caattcggtt
    22201 caatgacact tgcctgcaga aaacggccgg tgagcggttg atgctgggca atggcataac
    22261 gctggctatc aaagccgcca tcattaagtt gaccatgaac tgcacgaact ttgagtttca
    22321 ttgaccatac ttgtccggca caaaccgctt gcggaagata ttcgccatac agtacgaggc
    22381 ctggcgcagg gaatatacgt cgaccttgta gatgagtaat ttgaccgtaa tgagtggtca
    22441 tgccgtcagt agcaatgatc tcaacaattg catcctgcgt cgcgccagtt aaggtttctc
    22501 ctgcccacaa aatttgcttt gctgctaata tgccccaaac gaaaaacagc aacgtcagcg
    22561 cgatataacg gacggtttta acagggataa atgccagtac acaggcgaag agagtcagaa
    22621 acgcaagggt tactgtccct ggcaattggg gcaaaatcag caacggaaaa attccgcaaa
    22681 ttatgcatac gccgactgtc gttattttca tgcaccctcc ctgtttatag aaagtgtgca
    22741 actttgttga acggttgtct ggtgggagtt ttgcgttccc cgaggcacgt tcagaagaat
    22801 ttaacgatag ggtgaaaact gctcaaaact ctgcgaggca gcttccagtt ccagattaga
    22861 gaaatgaaaa aagcacccga caggtgcttt tctcgcgttc aagtttgagt aaaaacttaa
    22921 ccgtaaatat tggcgcgatc gcgcagttct ttacctggtt taaagtgagg aacgtatttt
    22981 ccttccagtt ctactttatc gccagtcttc ggattacgtc cggtacgtgg tgcgcggtag
    23041 tgcaaagaga aactgccgaa accgcggatt tcaatacgct cgccctgcgc aagagtcgag
    23101 gccatatgct ccagcatctc ttttactgca tcttcaaccg tcttggcggg aatgtgcgat
    23161 tgctgggtgg caagtctttc tatcaattct gacttggtca tgattcctcc ggttccttaa
    23221 aggcaaatta agcggctgct gttgctacat tgattaaggg cggccgtagc cgcccttagt
    23281 gcttgattac aggacgaaac ctgcaatctg tcaagtaaac tcaacaaact tcggaataaa
    23341 aatcccgaag agtcagagaa ttactcgcct ttagctgctt tgaaagcttc agccattgcg
    23401 ttgttggaga agtttgcatc ttcctgtttg ttaacagttg cgattgcatc tttctcgtca
    23461 gcttcgtctt tcgcacgaac agacaggctg attgcgcggt ttttacgatc aacgccggtg
    23521 aatttagctt caacttcgtc gccaacgctc agaaccaggg tagcgtcttc aacgcggtca
    23581 cgggatgctt cagaagcacg caggtaacct tcaacgccgt cagccagttc tacggttgcg
    23641 cctttagcgt caactgcagt tactttaccg gttacgatag cgcctttctt gttcagagca
    23701 acccagttgt tgaacggatc ttctgcgagc tgtttaacgc ccagggagat acgttcacgt
    23761 tctgcgtcaa cctgcagaac aactgcagcg atttcgtcgc cttttttgta ttcacgaact
    23821 gcttcttcgc ctgcaacgtt ccaggagatg tcagacaggt gaaccaggcc gtcgatgccg
    23881 ccgtccaggc cgatgaagat accgaagtca gtgatagact tgattttacc ttcaacacgg
    23941 tcgcccttgt tgtgggtttc cgcgaactgc tgccacgggt tagctttgca ctgtttcaga
    24001 cccagggaga tacgacgacg ttcttcgtcg atatccagaa ccataacttc cactacatcg
    24061 ccaacgttaa caactttgga cgggtggatg tttttgttgg tccaatccat ttcggaaacg
    24121 tgtaccaggc cttcaacgcc ttcttcgatt tcaacgaagc agccgtagtc ggtcaggttg
    24181 gtcacgcgac cagtcagttt ggtaccttcc ggataacgtt tagcgatagc tacccacgga
    24241 tcttcgccca gctgtttcag gcccagggat acacgggtac gttcgcggtc gaacttcagc
    24301 actttaacag tgatttcgtc gcccacgttg acgatttcgc tcggatgctt aacgcgtttc
    24361 caggccatgt cagtgatgtg cagcaggccg tcaacgccgc ccagatcaac gaatgcaccg
    24421 tagtcagtga ggttcttaac gataccttta acttccatgc cttcctgcag gttttccagc
    24481 agctgatcgc gctctgcgct gttttcggat tcgataacgg cacgacgaga aacaacaacg
    24541 ttgttgcgct tctgatccag cttgattact ttgaattcaa gctctttgcc ttccaggtgc
    24601 agagtgtcac gcaccggacg aacatctacc agagaacctg gcaggaacgc acgaataccg
    24661 ttcagctcaa cagtgaagcc gcccttaact ttgccgttga taacaccggt aacagtttca
    24721 gcatcttcgt aagctttttc cagcgtgatc caggcttcgt gacgtttagc tttctcacgg
    24781 gacagcagag tttcaccgaa gccgtcttct actgcgtcca gagcaacgtc aacttcgtca
    24841 cctacctgga tttccagctc gccctgggcg tttttgaact gctcagccgg gatggcggac
    24901 tcagatttca gaccagcgtc aaccagtact acgtctttgt cgatagcaac aacaacgcca
    24961 cgaacgatag aacccgggcg ggtttcgatt tcttttaagg actcttcaaa gagttgagca
    25021 aaagattcag tcatgtttaa tcttcaggtt tatatttaac gtccacctgg ctccatgccg
    25081 gatggggttg tttaacatac ccgctgtcat tccattgcaa cgggggtact gcaaattcgg
    25141 tcgcttatgc gagagccaat ttctggcgcg cgtattgtag cgctttttca atcacttgct
    25201 caatgcttaa ggtggtggaa tccaacacta aagcatcggc tgccggaacc agtggcgcta
    25261 ccgctcgatt acgatcgcgg tcgtcacgtt ctttgatctc ggccaaaagg cgctcaaagt
    25321 taacactaaa gcccttctcc tgcaactgta gcatgcggcg atgcgcacgt tcttccgagg
    25381 aggcgtcaag gaaaattttc actggcgcat cagggaatac caccgttccc atgtcgcgcc
    25441 catcggcaat caggcctggt aattcgcgaa acgcgcgttg gcgacgcaat aatgcttcac
    25501 gaacgcgtgg gaatgccgcg acttgtgaag cagcattcgc cacctcctga gtacgaattt
    25561 cgccgctgac atcttcccct tcgaggatca cttccagatt gccgttggtt gacacaaaac
    25621 gtacatccag atgggatgcc agcggcacca gcgcatcttc cgatgcaaca tcaacatggt
    25681 gatgtaatgc cgctagtgcc agtacgcgat aaattgcacc cgaatccagc agatgccatt
    25741 gcaacgcttc cgccatagcc ttacacaagg tgcctttccc tgcaccgctt gggccatcaa
    25801 tggtaataac cggggcaatt gccgtcatct ttatctcctt aaaacaggcg taccgttaac
    25861 ataaccgcgc gcattatacg cgccgacgcc acaaatcgtt aacgttgtgt gcaaaaacca
    25921 gttttgtctg tattcagatg gggatttatt gcgcaattat agcgggctgg cagaagacca
    25981 gcccgaaaga tgacaatgat ttacttacca gaggcgatac gatcacggat gtgttgcgca
    26041 cgctctgttg atggtgggtg agaatcaaac atggactggg tgtgaccgcc atccaggcta
    26101 gcgagttttt caaagctacc aaccagcccc tgggtactga tgccacgttt cttcaacaga
    26161 tcaaaggaga aatcatctgc ttctgactct ttatcacggg agtatttagc attgatagcg
    26221 ccttctgcga tatcacccaa ttgtgagcgg gaaagctggg aagccacacc gctggtagct
    26281 gaaatggcat cgcgtgcggc cacgatcgca taagaagctt tcatttcagc cagcgagtga
    26341 cccaacgcga cgtggcccag ttcatggccc agaacgcctt caatttcgtt gtcgttcatc
    26401 atgtccatca ggccactgta gacacgaaca caaccgttcg ccatcgccca tgcgttgacg
    26461 tcgctggtca tataaacctt atagttgact ggcgtgccat taatattgtt acccaatgct
    26521 ttggcgattt ttgccagacg tttcccgtac ttgctggatt tgcttgccac tttattgccg
    26581 ctgtccattt cgacacagcc ctgattggcg attgctttag catcagcatc gcttaatgtt
    26641 gcggctttat aagcattcag acctgagctg atagccaaat cggtattaat accgtgcgta
    26701 ttctgacatc ctgtcagtaa ggctgcagag gtcgcaatcg ccagcaataa tttagtattc
    26761 ttctgattag acttgagata aatgacaggg aataagtgag atatttatgg gaagaactgg
    26821 gtcaaaatgg gaagagacta ggaggaatat gcaataacct tacagtatgt gaaaatcaga
    26881 ccggcccgaa aaaaaaacag aactcgcgcc agcctgattg cagatattac tcttttttct
    26941 ccgtatctgc atcgggttca tcagcaaata gcttgccctg catccgatcc agttcttctt
    27001 ttcttacccg cttaaccacg ctgtagaccc actgaagcga aacaccaaat ttgcgggcca
    27061 gttcgtggtg gttgcgtccg ttaaactccc tgaagatttc ccggtcgcgc tgactgacct
    27121 tccataccat gcccatcggg aaataaacgt tttgcccgcc ccagacctgc atcattcggt
    27181 tcgcgacggc ctgaccaatc tggtcggcaa cttcgggctc aatatcaata atctcgcgaa
    27241 cggtctcaga ggtatgctgt gccagttcca ccaggagttc cggcccctta cttcgaaact
    27301 gattcaggtc gctcatgttt gactcccgca gctctgcgct gccacttctt cagtttctca
    27361 ataacactgc ttgcctgttc agtactgagc cagcgcaggg cgctgatgcc cgtttcccgc
    27421 ttgatccacc tcgctaatgc attttctgaa cggtcacgaa caatgccggc agcagccatt
    27481 tcaagccata gcgcacgaat tttcctggac tgcggatggt tatcaagcgg taaaccggag
    27541 ctggcttttc tggctggttt aacgcgaaag cctttctttt tcatggattc cagcacgcag
    27601 tttagttgtg tggtatccat tcctttggtt gaggctttac cggtcagccc ctgtaacatc
    27661 tggcggtagg tgtcttcatc catacccagt tcattacggg caatatggat aagctgtatc
    27721 aggcgttttt tctgcatatc atctcctttt tttcagtctg tcggcaacaa tgtcggttgc
    27781 agctggcagg gtgactggcc agaacaacat gacggcggtc atgtacagga tgtaatgcgc
    27841 ggtgtcgtag tgcctgccat agcccaggga acgatgaagt cttgcgctgc atgatcctgc
    27901 gtacatatac cagaaaagaa aacagacaat ggtttcagta gtcattctga atacctcccc
    27961 attcgatatg aatattacgg gcagcaatga cagggtcgtt attccaccat gcacctgaca
    28021 tgtatttttc aacctgttcg cgtccggcaa taacaccaat tgtgatcccc ggcctgacgt
    28081 tcttaaaaaa ggcgcgggca aaaaggtatc tggcagatat tcggcaggct tttaatttcc
    28141 ggcttttacc tgatagcgta atcatctggc ctccagtttc tgttgttcct gcccactgac
    28201 cgggcggtgc agtctgacgt tctgcccttc acgaaacccc gcatagcgcg aggcgtcgcc
    28261 attgcggctt cttcccggtt tacgcgccct ggtggtttgc gtctgcgggt atttatgttc
    28321 cagccactgc tgcatcagtt cacgctcatc atcggtcagg gcaaaggact gtatttcact
    28381 gataacggcc agcacccagc cttcggcaaa ctggtctcca cggctggtgc gggtggcggt
    28441 ttttattctt ttgttctgtg cactgatata ctgctgacgc gcctttttca gctgacgggc
    28501 cagcacttcc caggtgtatg cagccagtgc cgcacgttcc cggttgccgt agaaccccac
    28561 agacggatgc gtgccggggt gaatgatgga gttaacacca aatacctcgc ggatgatgtt
    28621 catcaggccc agcatgtagc gcggtggacg gagactgcct gtcggccagt agtgactgat
    28681 ggtttcatca atatcactca tagcaatgtc ggaatgtgtg atgccgtgaa catccatcag
    28741 tttacgggct cggcgcagtg ccagagcggc ctcgtgcggg ttgccggatg cggccagcgc
    28801 cagcaacttt ttcagtttct caatgtgttt attctggtct gtcattgttc tgtatctccg
    28861 gtatttttct gccgtttcca tgcccggaca gcgtcggaca gctctttcag gctgtatgct
    28921 gctttaagct tttcccataa ccactgtgtt gttatgtgca tcagcagggc agccagggct
    28981 gcccccgcac tgaggcatgt cgccaggcca gtaagaatca gtgtccatgc ggtgatttcc
    29041 ctgagtatgt cagccattga atgcctcccg gttactcgtt cgtgtaaatc acgcccagtc
    29101 gtgcagccag acgttccagt tttttctgtt tgtggaagtc aatcagccgg tccatcccct
    29161 gaaggcgcag ttgctctgtc atgatttcca cgtctgccag ctctgccgcg aggtcacttt
    29221 cgctgccctg tccgttcagg ttgcgggcgg cactggccgc cagttcagcg gcctcttctg
    29281 ccagtttcag ggcctgtgcg tccggcccga aacgctgcag ggccagacgg tagagggcgg
    29341 tgcgggtgag ttcggtgttt cgtgtcatgc cgcgccctca gtgcttccgg ctgacggtga
    29401 tgtgcaggcc gccttctgca gtggtttcca tccggtacgg cacctcatgc tctgccgtgt
    29461 gggtgagtgt gttcatcagt acctgcaggg cagcctcctt tccgttggtc gccacaatgg
    29521 cctgtgtggc catgctgatt agcgccgtca ggacgtgctt cacatcggtg aggtcgcggc
    29581 attcacactc gttgacatag tgttcaacaa gggttcgggt gcgctgtcgt gcttcctgtg
    29641 gggtaatcat tgcgagtcct ccctgtcagg gcgggagaat tccatgacgg gcacgtctgc
    29701 cgaaaaatgc tggctgcagt acgggcagac cagggtgacg cgtaccgcag ggatgtggta
    29761 tttaccggac atcacggcga tggcgctgtg aaaacgcagg gctgttatat ccctctcgca
    29821 ctgaatacat ttaaatatca tgatttaatt ctcctctgtt tccggcgtgc agaagcccgc
    29881 ggcgctgacg tcggaataaa aaagaaaatg tttttattaa ataattaacg tggtgtgttt
    29941 actgcacatc ctgctcaaaa ggaattattg aaaaatcctc aatgtcgctt ttaatggaaa
    30001 taccgggaat atttttcacg gcctcttttt cattcaggat agcgtcttta tttatttcct
    30061 cttttacacg aataaagcgc tcaagcccca gacgtctcag taattcaata acattatccg
    30121 ccccacggat actgactgat ggcggacggt ttcgccactg cacctcgccg gtggtgaggt
    30181 tagcgaactt caccttcccg ttgccggtca gttcatcacg gtgtgcctca caccatgtct
    30241 gaataccgga ctgcagttcg gccatgcgtt ttttcaggct ctcggtgagc ggggcataac
    30301 gtgcggtgat atcgccaatg gcgtcattca tttctgtttc agccctgacc agttcacgtt
    30361 gtgcgtcacc gagtagtctg attccctcaa tgacctcttc acgtgtcccc ggcacccaga
    30421 gtgctgctgc ggccttgata cgttttgcac cttttgtact ttttgccatt ttttatgatt
    30481 tctccagttg tgctgattac cacaaagatt ccggccacac gacgcgacag ccgtgcagtt
    30541 cgaaaacgcc ctgacggaaa tatcccctgt ggtcatgtcc ggtatacaga taacaggcct
    30601 ttccctgctc aagcatgcgc atgcaatgcg cactccggga aacgcggatg acaggtttgt
    30661 tacccctgat ggtgatgctt tgtacatccg tgttcgtcgc cttaagcgcc ataatggctg
    30721 actgcacttt gctgatttgc tggttgatac ctgtggtgga tttcattatt aaaccccttt
    30781 gacaacgtca gcgttgacct gtggaacccc gatttcagcg gccagattca tggcggctat
    30841 taccaggtta ctgacggcca gcggatacag caggctgacc atatttttac ggtgacttcc
    30901 cggattgctc aggcgggcac gtatggcatc cactgcaccg gcgtccataa tgtccgtcag
    30961 ctgtttaccg gcccgttgca gtttgaacgt cagaaattct tcaaggttat tgtccagagg
    31021 cagaagttcg accacctcac agcgctgaac gacttcacgg acttccatat tgcgttcaga
    31081 cagttttgtc gccagttccg gctggccaat cagcacgatg gacagcagtt ttttgaaacc
    31141 ggactccagc tcaaaaaagc gtttgaggtg tttcagtgtc ggaatgggca gactgtgggc
    31201 ctcctcaatc accagaacgt ggctgaaccc cgcctggctg ctgtctttca ggacgcgatg
    31261 caactggcga aaacgggcgt cctgactgcg tctgatgctt tccagtggtg cgatggtact
    31321 gataatggct tcggcaatag ctgctgcctt cagggttttc cctttcacat cgttgtcttc
    31381 catagcgatg atgtatggct cgataacaat taccggcgca ttctcgcggt tgatacgttc
    31441 agtcaggtcg cggcgcagcg tggatttacc cgcaccggac tcaccgatga cggccataaa
    31501 cccaccatga cgggctgtct ggtacagcgc ctcacgcacg tagcgaatgt ccggggtggt
    31561 gaacacatca tcagaaccct gcatggcttc gtcggcgaac gggtcacgga aaagaccaaa
    31621 cgcttttttg gttgctggaa ataacacctg ttttttgagt aacatattct cttcctcact
    31681 gaggctcgtt ttatctgtgg tacccgctgt acggggcgtg gccgcgccct gtacagcatc
    31741 aaaactcttc gttgtatcaa tcccctgact ttccagccag gacgcaagac gccggcgcac
    31801 ttctccgggg ctggtgcggg gccacgcgtt atgattcaca atctgggcca gcgtggcctc
    31861 agaaacatcg acagctctcg ccaccaccgc ctgtggaata cgggcctctt tcagttgctg
    31921 cttcagtacc agcatgtttc cctcctcagt tgccgttaac aatgctgata acactgctgc
    31981 gggccggtgt ggtcagcgtg gccatgactt catccagtgc ggcttccggt acgccgtccg
    32041 ggtactgtgc cgttaactgg cggtaatgtt ccggcgtcca ggtaaggccg tcggcgctga
    32101 acttatcgcg cagggctttc gcggcctcca catgagtcat gggacgttgt tcagtgcgcg
    32161 gcccgcgtac gtcagaggcc tgaccacgct tcggcatata ggccggaagt gtggtgtcgt
    32221 cgatatgttt atacgggtca agccgcccgc cgaacggcag cgccttcgcc ttgcgtgcgg
    32281 cggctgcatc tgcggcgttg tctgtaccgg taaccagcgc ttcggtttct tttgccgcca
    32341 tctgtgccgg ggtttccggc agggctttgt aactttcgcc aaataccgcc gcgccttcag
    32401 caaagccaaa ctcgttcttt ctgacctctt cgaccaggaa gaacgtctcg tggccgtcct
    32461 caccggtcag aaccacctgt gccacatcgc tgcgccatgg gttacgggta atcatcagtt
    32521 tttcaccaac cagtacgccc ggtaccgttg atacgtcaaa ttcagtgccc cggaacgaga
    32581 cacgaagttt tggcgtgact ttgcggagtt ctggtgccgc cacagccagt tcacgacata
    32641 cctcaacgga aggcgctttt ttcagctgct cagcagtaat cttcagccag atatccgtgc
    32701 gggttttacc gtggcggctg tgaacagccg tggcgttaaa gtggctgcgc catttcgcgg
    32761 ccagcgcgtt gagttcttcc agactgtgaa ccggccggaa cttcagaccc ggctccagct
    32821 tgcgttcgat aatgtcacgc gccttttcca cctgtccggt ggcgcgggcg ttatgcggct
    32881 tgtgcgctat caggtcgatg cccagtgagc ggcacatgtt tttcgtcata cccgcggtgt
    32941 ttgccgagcc ggggtcgaga tagagtattt tcggcacgcc gtgcagcacg tctgcgccgc
    33001 cacgctcctg catggcgttg ataagcacag aacacaggtt ctcacctgat tccgcgcccg
    33061 tcacatactc aacgtaaatc cagccgctgg catggtcggt aatctcgtaa ctccacacgc
    33121 ggtcactggc gatacgggca aggttagcgg gcttgttctt gtagaacttc gcgctgtcca
    33181 tcacctgcag ccctttatgt ccattgctca ggtagtaaag cgtgcagagt gaggcgtcaa
    33241 tctgccagac atgattggga tgcagactgg ccacttcggt atgtggtgca ggggcatcca
    33301 gttgttccgg gtgcaggcca tagttacgca gagcacggct gatggcatct tcagacaacg
    33361 ggaaaaactc actggtggtt tcatctgttc tgcctgcggt gataaagccg ttagcccgca
    33421 gggtttccac tgcatctgcg atggaataga gacgcttacc gttcttgcgg gtggcctcac
    33481 gcagtgtggc agatatcagc gcggcttcgt cgcgggtcag ggcgctgcgc ccggcatcgg
    33541 cgcgtttttt gcgtttatca gtcacagata cctccttcag cctgcgcagc agagtggcgc
    33601 gggacatgcc aagttcagca caggcagcgt cgtatattgc accgcgttta ccatgccccg
    33661 cgtcacgtgc cgcgcgggct gtttcaacca gtttttcagt cagtgccggg gtcatagctt
    33721 gtcttccctg ttatccgatt ctggcggcaa tttttctggc gaggtcgcac agtgtttcgc
    33781 catcgcaggt tttcaccacg gtatttaccg gttgcggtgc aactaccggg cgtaatgctg
    33841 actgattctg cagacgtctt atctgctgca tcagcatcac ctccatcgtc agtacaaacg
    33901 ggtgcgtctc ctgtgcgggt acgcagattt caccggaagg ggtcaccacg cggaaaccct
    33961 gcaccatctc cggcagcaga ttacacagtg cgtgccccag tgcctccggg ctgtccatca
    34021 gggtattttg tgtgttattc gtattcatta ctgcatatcc tccggtcggt tgatttcagg
    34081 ttccggttcg gtcagccagg cgggggcatc gttacccgat ggagcggcct caaggtcaaa
    34141 cgtctcacgt aatgcatgaa cactgcgttc aatctggcag accagaccgg ccatgaaatc
    34201 tctgggggta tcgatcatgt ttttggtgca gtattcacac agggtctcaa aaacactgga
    34261 cagccggacg gcgatagccg attcggcctc aaccgctaat gccgtcactt ccgcccgcaa
    34321 ttttttcagt tcttcgtctg gcggcggagg ttgcaggcgc gatttcttct ccagttttgt
    34381 ggccagttcg ttgatttttt cgtcctttcc ggcaagcacc tgttgctgag ctgcgttggt
    34441 ttcgcgcgct tcacgcaggg cggccttcag ttcgcggctg gtcatgcgat caatatcatc
    34501 aagcgttgca ccggcgacgg ttccaccatc agctaatgcg tcgagttctt cgtcatccag
    34561 aaccatcagt tcatataact tggtttttcc caaaacgctc agcgctgagc gttttggctg
    34621 ttcatctcca ttgccgagaa atttcacgct ggcctgcatc atgcgacgag ctacctgtgg
    34681 tgctaatccg aggtcgtttt ccagaatatt tgtgaaatca ccatgcggtt cattttcttt
    34741 taagatgatc agccgcttac ccgcttccaa catagattca gcactctgcg ccatataaaa
    34801 acgtgcttcg tgaacgatgc gttcacgttc ataaggcagt ccatcaccaa actgctgcat
    34861 gatctccatg cgatgctgtg tcatggcatt caggctgacg ttgagatcat ccgacagcgg
    34921 tacatcggcg ttcagttcag tgttaatcgg tgatttggta cgtcccattg attactcctt
    34981 acaaacgact acctgaaatg acacgttggt taatttcgtt aatacgatcc tgtgcacgtg
    35041 ccatctcgtt actgtgggcc atggcgatct gcagtaactg gatgcccggt gcaaaacgtc
    35101 cgttctccag tttcagagcc agcccttctt caatgagggt gttgagtgcc cggttgatgt
    35161 ttgccggtga ctcgtgcagt gctgtcgcca gttcaccgtt agaaataccg ttcagggcat
    35221 gaccgcgcag cgctttgagt acccggagga tgcgactgcc ggagcttgaa acattcgtct
    35281 tactcatctg catacctctt ttgcgatatg tgataacctt ttacaaagac tcaaaatatt
    35341 taggccgcct gagctgttga tttcagtccc aacttcacgg cgatttcatg ggatttaccg
    35401 taacgggctt tggtctgccc gttgagaacg cggtatacct cattgcggtt gtagccgttt
    35461 tcttctgccc agcgggtgaa agtgatcccg cgctggcgga agagagcttt gacttgttct
    35521 gcagtcatcg ttgtctcctt tgttgatgca atgatgtttg ccttatatgt gttagattat
    35581 tgctcataat tatgagcata tcaagataga gattcacttt tatgagcaaa gatataggag
    35641 agcgcgttat ttctgtgagg aagaaagcag ggttgaacca gagagaattt gcagctcgtt
    35701 taggtatttc taatggtggt atcagtcaga ttgaaaatgg aaaggcgatg cctggagggg
    35761 agtttctgtt aaagatgcat caagagttta atgttgatgt aaattggttg ctcactggaa
    35821 tgagcacaga tggtatgact agaaaccaga atcaaatttc cccagaaaaa caaaaactaa
    35881 tagatacttt tgacgacatg acaccagacc aacaacgctc atttcttgag attgggcgat
    35941 tctatactca gccaaaacca ggaaaaatcg caggctgata ctgacccgga cacaaaggac
    36001 aggtggttga tctggatgct ttcagaaaac atcgccagtg acatagtgga agttgtttgg
    36061 tttaccggaa agcattgtgc tttccggttt tgtttcagaa gttgcagatt agcagttcac
    36121 ggcgcggcgt gggtttaccc gccagactgt agttgatatt cactgtctgt atgttcagtc
    36181 cagtgaacac ctcgcgcatc tgcgggatgt cgttcaccga aattatcatt tttcctctga
    36241 tgcaccgggc cagctctgcc agccgcgagt agttcccttc aggaaaatcc acaccatagc
    36301 cttccgtacc caggtacggt gggtcgcagt agaacagcgt gtgcggacga tcataacgct
    36361 caatgcactg ttgccagtcc atgtgttcta tgactgttct ggaaagccgc aggtgtgccg
    36421 ctgacagttc ttcttcaata cgtagcaggt tgaagcgtgg cggggatgtg gtggaggtac
    36481 cgaagctgtg ctctgccacc ttgccgccaa acgcctgctt ctgaaggtag tagaaccgtg
    36541 ccgcacgctg gatatccgtc agtgtttctt ccggggtgat ctgcagccat ttgtagatct
    36601 gacggctgac cagcgcccat ttgaactggc ggacaaattc ttccaggtga tgctttacca
    36661 cccggtacag attcaccagt tcaccgttga tatcattgat gacttcgatc ttgccgggtg
    36721 tcttaagaaa atagagcgct gctgccccac aaaacggctc cacataacat tcatgcgccg
    36781 gaaacagcgg cagaatgtgt tttgcaaggc ggcgtttgcc accaatccac ggcacgatgg
    36841 gtaatgtctg cattttcata atctgcaagc cttttacaat tattaaaaaa tatggcagtc
    36901 tggtcaggtc tcgcgagact gactgaacct tggtcggctc acagcgcatt cctgtggggc
    36961 gatgaccagc ccggctttcg ggtgccgggc tggtcgttct ttcatgatgc ggcagggatg
    37021 gcgggatttc tgttaatgtg gtttagggat tatccggggc gattttctga ccttatccgg
    37081 tccagggcat aagtaatacc ttctgcaaaa acagaagtat caaactgctt ttgtattccc
    37141 tgaaaatgaa aagcggcacg acagacactc agttctccgc ggtataaccg gataatatct
    37201 tccagaacat tgttcactgc ttcagcacgg cgctgatgtt ctgttaacgt taatcgggga
    37261 ttcatgatgc actccttaaa tgatgatttt tatgtactca ccggcaaaat attctgccga
    37321 ttactgaaca cgcatccggc acctcaggtt ttgatttatt ctggtttttt cgatatcccg
    37381 gaccaggttg atcacgacca gaaaaagtgc cggtgtttta ttgatacgct gatatggctt
    37441 cgggataaca gctatattcg ttactctcag ttgctggctg tgggagcggc tgatgtcgtc
    37501 ctcacggaaa aaacgctctg tctgctcaat gccatgccga cctttctgca gccccggccc
    37561 gtaccattta aagagtcact tctggatgca gtaaaaaccg gtgaaaatgc agtcatcgct
    37621 gaatgcgtat cccggattat gcgttacgtg tttaatgaac gtaagtgagg tttatccgct
    37681 gtctgcataa tcccgatagc cagtgcgagg ggaagtaatt ccggggaaac tctttcaaac
    37741 agcgatgccc attctcctct cgccatcact ctgtccagcc cgccctccag ttgcatttca
    37801 gcaatcttcc tgatttcccg gaacaacgcc gctttgatct cttcatgctc agctttattt
    37861 tccggtgtca gaaggtattc gtcgaagaac cggggaggct ggttaatcgg gatgtgttcc
    37921 tgtttgccgt acttcgggga cgaacaacat tctgttgact gaccagtgag tttacgtaac
    37981 tccttcatga gcagctcctg atcgtaaact gtcatcagtg ccgcaatggt ggcatgcagt
    38041 gcatcgggca gtatccaggg ttgccggccc gtggggcata taacatccag cagctcattc
    38101 gtccgacaga tacgctcctc gccgtatgac aacaggccct gtcccgtgta ttcctccagc
    38161 ctgatcactg tgccagcccg tggtttctgc catgtgctca gatcatcccc actcatacgg
    38221 cgctcaccgt ccacgtctgc ggcgtcgaca atgacgctgt ttccgaattc ctgtttcacc
    38281 acttcctcta ttcgcgccag tacgtaactt ttaccgctgc ccacaggacc ggacacggtg
    38341 acagtgatga ccggattcag tgtctgcgtc atatcgtatt ctcctctgtg aataattcat
    38401 cgtttatcct gcacatcccg tatccccggc tctcttaacg cgctttaaaa tccttcgcgc
    38461 cctgtatttg tgatgctgtc tccaccagat aaggagacac acatgaaaaa cctgaaaaaa
    38521 ttcattcccc ctgttaaaaa acctcgcctc agcggctggc tgctgacctc agtgctgttg
    38581 ctgggcacca tcgctctggt ctcaccacag cagctgcctg ttgtgatcta caagctggca
    38641 ctcatcacgc tggcagcagt gctgggttac tggcttgacc gttcgctctt ccccaaagcc
    38701 cgtcccggtc agtacctgaa acatgacgac aggctgatgg ctgaagggcg tttcccggta
    38761 cagaccggcc ttcacctggt gttttctgct gcgttaatcc gccgtgcact gattgttgca
    38821 gcggtctgcc tggctgttgc gatggggctt taatcatgaa ctggccgcag atcacctgga
    38881 ttgtatgcat gtccctgaaa ctggctttcg aagcctttcg ggtcttcatc agaaccgaac
    38941 gcctgtcagt ccgcgccggg acctttctgg ttcatatggc atgggtattc tttgtcgcaa
    39001 tgttgctctg gtgtggcggc tttttcagcc aggcatgcgc agcacaacct ccgcaggctg
    39061 cgctgcagta tcgcgatgat gtgatccgta atgcccggct tgaatgggga ctgtctgcgc
    39121 cggtggccga tttcgccgcg caactgcatc aggaaagcgg ctggcgacct gatgcgatct
    39181 cgccggctgg cgctcaggga ctggcgcagt tcatgcctgc cactgccgac tggataagcc
    39241 agttgatacc gatgctgagc agtcgtgagc cgtttaatcc ggcatgggct atccgggcgc
    39301 tggtcagcta tgaccgctgg ctgtggcagc gtgtcagcgc cgccagtgac tgcgagcgta
    39361 tggccatgac actgtcgggc tataacggtg gtctgggctg ggtacaacgg gacaggcggc
    39421 ttgcatcaca gaaaggtctg gacagcaccc gctggttcgg acatgtcgcc acggtgaatg
    39481 ccggacgcaa tgcggccagc tggcgggaga accgccatta tccgcagcgc atcctgcgcg
    39541 aactggcacc gcgatatctc acatggggag gcagcagttg tgtggcatct ggttaaaaag
    39601 ctgccgtggc gcggcattct gctggccatt cttatcaatg cctttctggt cggcctgtat
    39661 gccatgggat acagaagtgg tcatgactct gcaaagcgtg acggtgatac cgcgctaagt
    39721 cagttgcagt cagcatttga cgcgtacaaa acggagcagg caacgcttga gaatgctgcg
    39781 ctgcgggcct gggccagacg gtatcaggag caggtggccg ccgggcagcg ggctgaagcc
    39841 ggttatcttg agcagattgc tcaactggag agccggaaca aacaactaca ggggcaaatt
    39901 aacgatgtca cacagcgctg gattgatgaa aaaggtaaga gtcatcccat tgagtgcgtg
    39961 tttactcgcg gtttcgtgcg ccagtacaac gccgcactcg gatatgacaa cgcatccgtc
    40021 gacaccggtc attcagactc agttgccgcc actggcaccc gctctggcac agcgaccggg
    40081 caacctgaaa ccactgacac ccggttacgc gattcgggtg tctcccagcg tgacgttctc
    40141 gccaacatca tcgacaacgc atggcaatgt cgtcgctggc ggaaccagat aaacgcgctg
    40201 ctggatgaac gggaaggatt acagaaatga cactgcaggt tgaattctgg acggtggtga
    40261 gttttctgct caccttcatg aggtttgtgg gagggctcgc caaatggttg ttcagtaaaa
    40321 cagaagaacg ccaggcggca cgattcgcct cccttgaaca ggccctgcaa caatccgcct
    40381 ccaactgggg cgagctggaa aaagaattta tgcgatttaa agcggattta ccgctgaatt
    40441 atgtccgtcg agaggattat atccgtggcc agacagtcat tgaggccaaa ctggacgcgc
    40501 tttataacaa actggaagtg gtacagcagt accgcaatac cggaggtcaa taatggtcga
    40561 tattacccgg gtacgccgcg aatccctgcg ctggagtctg ctggttgccc tgaacaagac
    40621 ccgcccttac accgccagcg agacgctgct gctggatgtg tcccgtgcca tctacccgga
    40681 caccacaccg ctggaactgc gccgcgaact ggattatctg gctgaccgta aaatggttga
    40741 gctggagaaa aaaccttctg gcgactggtt tgctgacctg acccgcctcg gcgtagacct
    40801 ggtggaatac accgtggaat gtggtccggg tattgcccgc ccggaaaagt actggagtga
    40861 ataatggcca gacgcagcac aatagaaaag ctgccggaag acgtgcgccg ctggcttgaa
    40921 cgggcgctga ctgaatccgg cttcagcggg tataacgagc tggagtcact gttgcgtgag
    40981 cgggggtacg tcatcagcaa atccgctatc catcgctatg gacagaagat tgagcgccgc
    41041 tatggtgcta tccgtgcggc aacagaagcg gcccgcatgc tgaccgaagg cgcagcagac
    41101 gatcaggatg cgcgttcgga ggctgtgata gcccttattc agaccgagct gttcgagagt
    41161 attgtccagt tgcaggaggc ggaagaaggc gaagtcgatc ctaaagaacg cgtggccctg
    41221 ctgtcgaagg tggcgaagaa tgtggctacg ctgtcccgcg cgtccgtcaa cctcaaaaag
    41281 ttccagtctg aagtacgggc cagagcgcag caggcagcca gcaacgccga gaaaattgcc
    41341 cgtaaggggg gactgtcaag cgacgcagta caggcgcttc gtcgcgagat tctggggatt
    41401 gccacatgac aaaatcatcc ggagtgattt taaacgccgc tggcggcggc cccgaaggga
    41461 tgagtcccat ggacgggagg aataaccttg ctcccgtttt gcctgatacc tcggcgctgg
    41521 atgcccctcc cgttctgttg ccttaccagc agcgctgggt ggcagacacc tctccgctta
    41581 aggtgataga aaagagccgt cgtaccggta ttacatgggc tgaggcatcc gataacgtac
    41641 tgaccgccgc ctcttctgcg ccagcaggcg ggatgaatgt gtattacatc gcttataacc
    41701 aggacatgac cgtcgaatac attcaggcgt gtgcgatgtg ggcacgggca ttcaactatg
    41761 cggccagtga aattgaagaa ggattctggg aagaggacga cgacgacaaa cacatcaaga
    41821 cttacaccat caaatttcct gactccggct ttcgtattgt tgcgctctcc agccgcccgt
    41881 ctaacctgcg tggccgtcag ggtattattg ttatcgacga agcggcgttc catgagcaac
    41941 tggacgaact gctgaaagcg gcgctggcga tgcttatctg ggggggaaag gtacgcgtta
    42001 tctccaccca tgacggtgac gacaatccgt tcaatacgct tatcggggat atccgtgccg
    42061 gacgtcaggg aggcagcata catcgcatca ctttccggga agccgtatct gaggggctgt
    42121 tccggcgcgt ctgtctgcgc accgggaagg aatggtcgga ggcatccgag caggcctgga
    42181 tggcatcggt gtacaaattc tacggtgccg gcgcatccga agagcttgac tgtattccgg
    42241 ccaacggtgg cggtgcctgg ctgtcccgtg ccctgataga gtcccgcatg tccgctgata
    42301 cgccggtatt gcgtctgacc tgcaaggaag gttatgaact gctgtctgat gaggttcgct
    42361 tccgcgagac gcaggactgg cttgatgagt atctgaaacc attgctggag gcactcccca
    42421 ctgatgcccg ctctttcctg gggcgcgact ttggccgtag cggtgatttg tcggtggact
    42481 atcccctgct gcaggagaag aacctggtac gacgcgtgcc attcgtactg gagctgcgta
    42541 acgtgccgtt cagacagcag gagcaaatca cctggtatct gatggatggc ctgcccggtc
    42601 tgctgggtgc agcgtttgat gcccgtggta atggtgccta tctggctgaa tacgccatgc
    42661 agcgctacgg ctccggccgg gttcagcagg tgatgccaac cgaaggctgg taccgggagc
    42721 atatgcctcc ggtcaaagct gcactggaag acggcaacct ggtggactta ccaaaggatg
    42781 aagacacact ggatgacctg cgggccgttc aggtggtgaa cggtgtcccc cgcgtaccgg
    42841 agcaacgctc aaaagcaaag gctgacggtg gtaaacgcca cggggattca gccatcgcac
    42901 tggcgctggc gtatttcgcc agccgtgaaa ttaacaaagg gccggtgaag gcaagctcac
    42961 gccgtcgtcg tcaggcggcc cgtatgctgg agggattctg atggcgaggg gtatctgggt
    43021 ttcacccgat gaatttgttg ctttttctga gcctcagaaa tcactgaccg cgcagattgc
    43081 ctcccgcagc cgcgcgatcg acttttacgg actgggcatg tatctgccca atcctgatcc
    43141 cattctcaag gctcagggac gggatatccg tatctaccgc gaactgcgca ccgacccgct
    43201 ggtcgggggc tgtatccgca gacgtaaagc agcgctcaaa tcgctggagc gtggactgga
    43261 gcgtggtcac gcctctgccc gggtcttccg tttcatccgc gacatgctcg acgatctgga
    43321 tctgtcccgc atcatcggtg aaatgagcga tgccgtgctc tacgggtatc agccctgtga
    43381 aatcatgtgg ggccgttcgg tcaggtcgtg ggcggtgacg gatattgtcg gcaaaccgcc
    43441 tgagtggttt cagtttgata cggacaactg cctgcgcttt cgggcgcgtg atgcgggtgt
    43501 ggagggtgag ctgctgtcac cgtcaaaatt cgtggtgccg gcacaggatg cctcgtatga
    43561 caatccttac ggtttcccgg acctgtccat gtgcttctgg ccggtcgcct tcaagaaagg
    43621 cgggatgaaa ttctggctcc gctttgccga aaagtttggc tccccgtggg tgatcggtaa
    43681 gcacccgagg ggcgcaaatg atgcagagat tgaaaaactg ctggactcca tggagcagat
    43741 ggtggaggac gcggtggccg ccatccccga tgacagcagt attgagctca gggcagcgga
    43801 tggcaaggca gacagcagcg aggtatttcg cgagctgatc acactgtcac gcagtgagat
    43861 ctccattgca ttactcggtc agaatcagac cacggaagcg aacagtaaca aggcctctgc
    43921 acaggccggg ctggaggtaa cggctgatat ccgcgatgcg gatgcggaca tcattcaggc
    43981 ggcagtgaat caggtcatca gaacggtggt caccctgaac ttcggcgatg tgccgtgtcc
    44041 ggtctgggcc atgtgggaac aggaggccat tgatgacacc cgtgccaccc gcgacgaaaa
    44101 actcacccgg gcgggtctgc gtctgacccc gcagtacttc aagcgtgagt accaactgca
    44161 ggacggcgat attgacgaga caccaccgtc ggaacgccag aataacatgc tgccgctgtc
    44221 atttgccgag gcgattgatg ctgatattca ggctcagcag cagcttgacg acgcgctgga
    44281 cattctgatg aacggaggcg cgttaaatgg cacgctggaa cccgtcctgg cacctctgtt
    44341 caggcgggtc gaaaacgggg ttaacccgtc tgagctgctg ggcgaactgg cggagctcta
    44401 ccctcagatg aacacggacg atctgcagga gcggctggcc cgcattctct ttgtggcaaa
    44461 tatccgggga cgtctgcatg agcgtgacaa cggctgaact ggcgtactgc atgacgcttc
    44521 ccccgaagcg ggcaatcaac tacctgaagt ccaaaggata tcagattacc tgggactggg
    44581 aagaaatgtg gcaggaggcc catgcccgcg cctttaccgt tgctaaagtg acccgcctgg
    44641 atatcctgga agatattcgc ggggcactgc agcaggctgt cgatgaagga aaaaccgatc
    44701 gctggttccg gcaggagctg gagccggtgc tgaagcgtaa gggatggtgg ggaccacgtg
    44761 acacgactga cccggtaacg ggtgagccgg tcaccattca gcagggcagt ccgtggcggc
    44821 tcgataccat ctttcgcacc aatatgtccg tactctacag cgccggtcgt tgggcggaac
    44881 agatggaaaa cgtcgacgac aggccgtact ggatgtatac cggcatcaac gacagccata
    44941 cccgcaggag ccatctggcg ctgcatggtc tggtgctgcg ctgggatgac ccgttctggc
    45001 aggcatttta cccgccgaac ggctggcgct gccgctgtag tgttattgcc ctgagtgcgg
    45061 cggatgtacg tgcccgtggc ctgaaggtta tcagctccgg ctctgccatg ggccaggaac
    45121 tgaaactggt ctcagagaaa accggcgaaa tgcggaacgt ggccaccttt aataccggca
    45181 ccacgaaggt gaccaccgac gtcggctggt cttatgctcc gggggcagca taccgtcccg
    45241 acctggcccg ctatcagggt acgcttcagc cactggcaca acaggaactg agaggataac
    45301 aatggcttcc gataacctgg tcagtatcac cattaacgat aagtccctgc gccggagcct
    45361 ccgtgcgctg gatcttgctg ccacagacct ggagcccgcg atgcgcaaaa tcgccggaac
    45421 cctgctggcg gaaacacagt ttaactttct tgatgagggg cgtccggggt ggatgccctc
    45481 gctggcagcg gaagaacgtg acgggcagac actgcaggat accgggcgtc tgatggggtc
    45541 agtatcaacc gaccatgacg accggcaggc tgttgtgggg accaacgttg tttacggtgc
    45601 cattcaccag ttcgggggta aaacggggcg taatgagtct gttgaacttc cggcccgccc
    45661 gttcctgccg gtgacggggg atggagaact acagcctgaa gtggtaatcc ccatcctcga
    45721 taccattgtc cgccatcttg aatcagcggc ccgtcgctga gttttctctc ttcaggcggg
    45781 tgatttatca ttgccagcga atgaggggct gtattacctt tataaaggct ttacagcctc
    45841 tgttttataa ccgcctccgg ttcaccgcat tgctttccct gtccttctcc cctgatgttt
    45901 tctaaagcag attaaaatcg ccgggcctgc atttctcaca aactgtctcc gacaacataa
    45961 cgcgggacag caaaatgtca gccattcaca tttttaaagc cggtactcat accgatatgc
    46021 acggcaaaaa actgccgttc acgccagacg atcttgccgc ctgcgtgaaa gcctatgacc
    46081 cgtccgtcca tgaagcacca ctcgtgattg gtcatcccag aacggaagac ccggcgtggg
    46141 gctgggtgaa agccctgtcg ctcagcggcg tcgatctgat ggcagagcct gcccagctgg
    46201 acccgcagtt tgctgagatg gtcaccgacg gacgattcaa aaaagtgtcc gcctctttct
    46261 acctcccgga ttcaccgtcc aatccgaagc ccggcgtgct ctaccttcgc catgtgggct
    46321 ttctcggggc acagccacct tccgtcaagg ggctgaaaca ggtgtccttc agtgagcagg
    46381 aagaaggtgt ggtggagttc gccgactggc aggccatcac gaatgcctcc ctgtggggaa
    46441 agctgcgcga ttttctgatc gcccgcttca gtctggacga ggcagaaaaa gtcctgccgg
    46501 aatggcagct caacagtctg cgcgaagagg cgtaccgcga cacactgtcg caggatgcag
    46561 caggtgcaca attcagtgag acaggcccgg ggccgtcttc cgcaagtaac gaggaatcat
    46621 cgatgacaaa agaagagatt gaagcccttc aggaggagaa ccgccgcctg aagcagcagg
    46681 ctgctgatcg cgatgcgcgt gatgcacagg tcagacagga gcaactgcat aaggacaatg
    46741 tggcctttgc agaaaaactg gtcgcagagg gccgtctggc tccccgcgcc tcctccgtgg
    46801 tggttgccct gctggatgcc gtcgccggtg gcgacaagcc ggtggagttt gctgaggggg
    46861 aaagccgcac accgctggcc accgcctttc gttcattgct ctccgacggg gagccggtga
    46921 tgaatttcgc cgaacaggcc acaaaagagc gtgtcggcga cacggtgaag gtggatgtgg
    46981 cagagtttgc ggaagccgat cctgagcgtc tggccctgca tcagaaagca gtggccctgt
    47041 ccaaaaaaga aggcatcagc tatgaggctg ctgtcgcacg ctgcctgtaa tttaaggaga
    47101 gagcatgtct gattacttaa aaggtaaacg tgtcgttgat ccggtactga ccagtatcgc
    47161 ccgtggctat aaaaatgccg cattcatcgg cgaacgtatt ttccccgtcg tgctgacgga
    47221 caaggaaggc gtgcgtgtac cgaccttcgg gaaaaccgcc tttgtggaat atgacaccga
    47281 gcgtgccgtc ggggcggaca gcaatgttct ggtccgtgaa aaaacaggca cgctggacct
    47341 ggtgctgggt gaacacgatc tggctgcgcc ggtggactat cgcgagcagg cggagtccat
    47401 gtttaacgaa gagagcaagg ccatccgtcg cgccacgaat ggcgtgaacc tgcgccgtga
    47461 acttatcgct gcccgtctgg ctcaggatga aaaggtctac cgtaccgggc acgtcaaaaa
    47521 actgacagcc agtgatcgct gggccggtgg taagggggac cccatcgggg tgattgaagc
    47581 cggtatggaa gcggtccgta cggccacggg gctgcgtcct aacctgatga ccatgggggc
    47641 cggcgtgatg gcgctgctga agttccaccc ggcgattcag gccgccatcg gagccaacga
    47701 acgcaagcgc atcaccacag aaatcctgca ggacctcttt cagatcgaag agatcgtcat
    47761 cggtgcccca gtctccctgc cgtccatgaa agcggcaatg gataagaaca gcgtgccggc
    47821 ggatatctgg ggagacaatc tgatgctgca ctatgtcggc aaaccgcagc cgggggcgga
    47881 cagcgcggac gagaacgagc cgtccttcgg ctacaccctg cgtcgtaagg ggatgcctgt
    47941 tgccgacaaa tacgacggag ccggtggcaa ggtgaagtac tgccgttata ccgatatcta
    48001 caaagtcgcc gtggttggtg gcgatgccgg gtatctcatt accggtatca gtaaataagg
    48061 aggcgttatg ggaaccactc agcaggtcat tctgatcaca accgtaacgg caggggcagc
    48121 actggcacag cagcgttttg tcggggcaga taataccccc tgtaaagccg gtgccgcagc
    48181 gctcggggtt gccgaagtgg atgctgttac cggcgacagc acgccggtga gcgttctggg
    48241 cattattgct gtcgaggccg gggccgctgt cagccgtggt gtggctgttc agtcagatgc
    48301 tcaggccaga gccgtgccgc agtccggcga cggtaaatcc tgtggtattg cacttgatga
    48361 agccgggggt gaaggcgacg tcattcgtat cctgcgcggg gtgtgacatg tactgcaccc
    48421 tggaggattt gcttgcgcag gtgccggagc ggacgcttat cgagctcacc agtgaagaga
    48481 tggacttcga ctcacctgca acagtgaata cccgtgtggt ggacagctgt atccgctatg
    48541 ccgacgagct gattgatgcc catctgcgcg gacgctatat cctgccactg gcagagatac
    48601 cgactgttct gcgggacatt gccatcacgc tggtccgtta ccggctctac gcccgccgcc
    48661 cggaaggtga cctcccggat acggtgaagg atgaccacaa agaagcgctg cggcaactca
    48721 gggagttacg tgataacagg ctcacgctgg ggctgccgtc cactcagaaa gatgtgcctg
    48781 agcctggcga gtttcgtgta cgcagtcgcc cggccacttt cggcggtcgt gacggtttac
    48841 tggagaaata ctgatgaacg ttctgcccgt ccttgatgcg gtactggccc ggttacgcga
    48901 gaagctgccg caactgcagg tggagtactt cccggagaaa ccggctgaat atcgcctgaa
    48961 ccatccggtt ggcgcgttgc tgttgagcta tgccggttcg cgctttgaca ggccggatga
    49021 taccggtgcg gtgatccagt ctcagactat ccagctctgc gtcacggtgg tcttccgcca
    49081 gctcaacggt aaaaaagggg cgattaatgt cctggatgct gtccgccgca ttctcggtgg
    49141 ccacaccccg cccggctgcc gccgccgtat ctggctgacc cgcgaggtgt ttatcggtga
    49201 agtcaggggg ctgtggcagt acgccctcga cttcgcgact gaaagcgtct ttatcgaaga
    49261 cagcgattta ccgtccggcc cgctgttaac cgaagtgaac tatgaggaaa gcgagtgatg
    49321 aaagaatacc gctattccgg cccggccagc ggcgtcacgc tgtcggacgg aaccgaaatc
    49381 ctgctctggc cggggaagac ggtttccctg ccggaggagc atgactacgt gaaggtactg
    49441 gtggcgctga aacatctgac gccggtacct gaagagacta aacccgccgg cacaccggct
    49501 gtgcagtcac caaagcgcag aagcagcagt gacagcgaag tgaaaacgga ggacacccat
    49561 ggcagctaac tatctgcatg gtcccgaaac cattgaggtg gaaaacggtg cccgcccggt
    49621 taaaacggtg aaatctgccg ttattggcct gattggtacc gccccgatgg gggatgtcaa
    49681 tacgctggta cagtgcctgt ctgagaaaga cgcagcggca tttggcagcc agttcaccgg
    49741 ctttaccatt ccgcaggcgc tggatgcgat ttatgaccat ggtgcaggca ccgttctggt
    49801 cattaacgtc ctcgacccgg cgaaacataa aacggcgatc gaggatgagg tggttacctt
    49861 tgacaaatcg acagggcagg ccagactggc gcatccggtt gtcgctaatg tggtggtgaa
    49921 aaacagtgaa ggcagcacca cccacacggc gaacacggac taccgtgttg atgcgcaggc
    49981 gggtgtgctc acgaacctgg gcaaggctat tgaggccggt ggcagcgtga aggtgagcta
    50041 tgagtacgcg gacccgtcga aggtgactgc ggcggacatc atcggcgggg tgaacagcgc
    50101 cggaaaccga accggcatga agctgcttaa cgacagcttc aacctgtacg gctatttcgc
    50161 caaaattctg attgcgccgg tgttctgcac ccagaagagt gtcgcagttg agcttatcgc
    50221 catggcagag aagctgggcg cggtaaccta cattgatgcg cctgtcggta ccacctttgc
    50281 acaggctctg gcaggtcgtg gcccggaagg caccatcaac ttcaatacca gctccgaccg
    50341 cgtccgtctg tgctatccgc atgtgaaggt atatgacccg gtgacaaaca cagagcgtct
    50401 ggagccgctc agccagcgtg cagcaggtct gcgtgccaga gtcgatctgg acaagggcta
    50461 ctggtggtca tcctccaatc aggagattct ggggatcacc ggcgtggagc gccagctgtc
    50521 cgcgatgatt gatgacccgc agagtgaggt gaacctgctt aacgaacagg ggatcaccac
    50581 ggtattcagc agttacggca gcggccttcg tctgtggggt aaccggacgg cagcatggcc
    50641 aacggtcacc catatgcgta actttgagaa cgttcgccgc accggtgatg tgatcaacga
    50701 gtccattcgt tatttcagcc agcagtacat cgacatgccg attactcagg cgctgattga
    50761 tgcactgacg gagtcggtca acgcctacgg tcgcaaaatg actggtgatg gtgcggtact
    50821 gggcttccgt tgctggtttg atccggcccg caatccggag acggagctgg ccgccgggca
    50881 cctgttgctg agctacaaat atacgccacc accgccgctg gagcgactga cgtttgagac
    50941 tgagatcacc tcggaatacc tgttaaccct gaaagggggc aactgatgtc aaagattgag
    51001 ataaaccgca tcacgaatgc caacatctat ctggatggta ctaacctgct gggacgggct
    51061 gaggaagtta aactccccga tgtctccatg attatgcagg aacacaaggc gctggggatg
    51121 gtgggtaagg tggaactccc ggctggtttt gacaaactgg aaggcgaaat caaatggaac
    51181 agcttttacc gcgatgcgat gctgtctgcc gcgaacccgt acaggtcgct ggcactgcag
    51241 tgtcgttcca gcgtccagcg ctacagctcg caggggctga ttgacgaaat cccgctggtc
    51301 accttcctga cgattatgtt caagaagaac ccgctgggga cgttcaaaca gcacgagaac
    51361 gccgagttct ccagtagctt cacctgcacg tatatcagac aggtactgga tggtgaagag
    51421 ctgctgcaac tggactatct ggccaacatc ttccgggtcg gcggtgttga tcaactgact
    51481 gactaccgta tcaatatcgg gggctgacgg tgagtgttga actgacggat aaaggaggac
    51541 gatgtgcggc actgggcatg tcaaatggta cgtggtttac cctccttgat attccggggg
    51601 tggaaaccct ttttaatacc cgtaaaacca atgacccgat tgactgcaca cgttcaaagg
    51661 cccgcaaact ggcggatttg attgaagcat gggagcctcc cgaccactgg ttctccggca
    51721 tcggcaaatc tgagggaaag acgcttctca tcgctttcct gcgtaactgc aaggggtttc
    51781 gcacttgctg acatcacagg ggctccggcc ccttcttctt aatctccttt aatatccgtc
    51841 acgcgcttct cccgacatac tgccctgaac ttacacagga gcacaatcat gtcacagacc
    51901 ccatccgata cttttaaatt gtcttatccc ttcaccactg ctgcaggcac cagaattgag
    51961 ctggttgaac tgaaacgcct gacggtaaaa gacctgaagc aggtgcgcaa aatcagcaaa
    52021 aacccggcag actgggacga accgctgatt gcccgcagta ctggtcttct cccggaggat
    52081 ctcgacaata tggatctggc tgattacctg cagttacaga aacgatttca gctcatcacg
    52141 gggatgggtg agagcaacca gggcgctgac gcaggcgcag gggctgctgg cgagatggtt
    52201 ccggtttcag ccgggggaga ttgatgccct cgatactgac gatctggaga tgtggctgga
    52261 gcaggctgaa gagcaaatca aaagcgagta cggcgacaaa tcatagtaca gacagccgcc
    52321 agtagcggct gttctgcgtt atcccctcac gtcttttcac cttccccgga ggttaaccac
    52381 tatgtcggga cagttttcag tcggcgttgt tatcggcggg atgattggca gcacattccg
    52441 ttctgcaatg agcggtaccc gccgtgcgct tgattccctg agcgatacct cacgccgcct
    52501 gcaggaacgt cagaacgctt taacccgtgc aacagaacgt tatggtcaac tgggttcttc
    52561 ccggatgcag catctcaaca gcgagctgct gcgggtaagc cgcaccatgg agcaaattga
    52621 gcgccagcag cgccgtctgt cagcggcatc cgctaccagt gatgcgctga aagctaaccg
    52681 catggcgctg tatggtcagg ggattgaagc gtatggcatg gcacagactg tttatcatac
    52741 ggtttcccct gccgttcagc agtccatgtc ttttcaggac aaaatgattg atatgtcgat
    52801 caccgcaaaa tatgacaata aaacgcggga tgcacttgcc ggacagataa aaggctgggc
    52861 gcttaaatac aatcagtatc aggatgagct gcaggaggcg atgggttcac tcatcagcga
    52921 caatattgat aatgtgtcag atatcggttt tctgatgccg gatattgccc gcgcggcaac
    52981 ggcaacacgc acgtctgctc aggactgggc aaaagtggcc gcagtctggc aaaactccct
    53041 gaaaggcgcg gccagagatt ttggtgccgt tcagaatatt atggcttatg ccggtgacca
    53101 ggggtcattt gaaatcccgg atcaggtcaa gtggatgcag tccctggccc caatgatggc
    53161 gggtattgcc agtggaaaag aggctgttgc tgaaatcggg gccagtctcc agatagcaaa
    53221 aatcggtgca ggttccaccg acgaagcagc caataatttt aaaaactttc ttaccaaaat
    53281 ttttgcccgc gatactcaga aacagtttgc tgatctgggt attgatttgc agggatctat
    53341 tgcgagttat aaagctgcgg ggatctctcc gattgaaggg atgttgagtg ttatagaacg
    53401 ttacctcaat gccaaaagcc ccgaagcgct ggccggcttc aaatcagcca tgaaaataaa
    53461 gaatgatacg gcaagagatg aggcacttca ggctctggcg aaaaactttg gtctgggcga
    53521 tatgttcgcg gatatgcagg tcatggcatt tatccgcccg atgctggcca acatggacag
    53581 atatcgagag atccgtgccg gtgctctcag ggctgcggat aacgatttgc ttgccagtgc
    53641 ttatgatcag cggctgaaat ctccccttga agccactaaa acacttatgg tcagcagtcg
    53701 cgatctggca attacgctgg gcgatcaatt agctccatct tttatttctc tgactcagga
    53761 cttgctccca ctcattcagg ggacaaaaca ctgggtggcg actcacccgc aatttgtcag
    53821 tggggctttt aagctcatca gtgcgctcct tgcgattaag atagcgactg ttggtctcaa
    53881 actggggctg aatctcctta tttccccctt tgtgaacgtc tggaaaactg ctgttttact
    53941 ccggaccaac tggcatcgac tgactaccgc actcggagaa ggtggcaaat tacgctggct
    54001 tgtcactgga ttcagccgac tgaccagcgg aggactgaaa ctcagcaaag ttctggcggg
    54061 cagcctcgtt cgcggtttta tgagcgctgc acgtgccgtt ctctggattg ggcgagcgct
    54121 gatgatgaat cccatcggtc tcgttatcac cgctgtcgcg gcagcagctt accttatcta
    54181 ccgcaactgg ggggcagtca gtggctggtt taaacagcgc tgggctgaca ttcaggaagc
    54241 ctttaacggc ggtatcgcgg gaactggtaa gctgctgatt aactggtcgc cggcaggcct
    54301 gctctataaa gcctttgcgg ctgcgctgaa atatttcggc gttactctgc cggcaaagtt
    54361 caccgacttc ggtggccatc ttatcgacgg tttgattaac ggtatcaaaa acaaatgggg
    54421 gtcgctcaaa tccagtgtaa ccggaatggg tgacagcatc agtagctggt ttaaacaatg
    54481 ctgggctgac attcaggaag cctttaacgg cggtatcgcg ggaactggta agctgctgat
    54541 taactggtcg ccggcaggtc tgctctataa agcctttgca gctgcgctga aatatcttgg
    54601 tgttgatctg ccggcaaagt ttaccgactt cggtggccat cttgtcgatg gtctgattaa
    54661 cggtatcaaa aacaaatggg agtcgctcaa atccagtgta accggaatgg gcgacagcat
    54721 cagtggctgg ttcagcgaaa agctgggcat tcattcgccg agccgcgtgt ttatgggctt
    54781 tggtgacaat atcgcgcagg gggccgccat tggcctgcag cggaccactc cgcttgcagc
    54841 tctggccggg cagcgaatgg ccagtgaact gctccccaga atgcccgtga gcattcaggg
    54901 gccagaaata cgggataaca cttcaggtgt tcgcttcagt atgccgttgc ccgatatcaa
    54961 tgggtttatg tcgtctgcta aaaatgcgat cggagccgta atcaatagtt tgtcttccat
    55021 gcccgctatt ccgctctcca cccgggcatc gattttacca gggcaacgtc tggcaaatga
    55081 gatgacaccg gatgttcccc gtatcccctc gcctgaaatc ctggctgccg gatattcagg
    55141 ccgtggtgca gctgcaaccg gcggtggaac gtctggtggt atccaggtca gctttaatcc
    55201 tcagtttttc ctcaatggca gggaaaccac agcgcctgca ggactgactg gtgccctgaa
    55261 tatgagtctg catgagctgg aaaaaatgct ggagcgtctg ctggctcaga aacaacgtaa
    55321 ggagtaccgc tgatgtttgc cgtactgggt gatattgagt ttgagctgat tacctactgg
    55381 gacggcttcg aggccacgtt cggcgtcgat tatgcggagc atgcccgcat cgggggtaag
    55441 cctggtctgc agttcgtcgg cgacaggctg gacgaaatcc agataactct ggttttccat
    55501 cagcattatt gtgtacccga tgtggagctg gcgagactgc gaacagccat gaaagcccat
    55561 caggcactgg cgctggtctt cggcaacggt gactatcgcg gctggttcgt gatcaccgat
    55621 gtgactgcaa ccagcgagca gactgacagt accggcaacg tgctggctgt cagtgccacc
    55681 gtgtctctcc gggaatacac cggtgacccg aaaaatcctc tgcaaccacc ggcaatacgc
    55741 acgaagctcc cgggtgtcgg ggcggtctcc ggtgccatac cttcaccttc aggggtggcg
    55801 cagttcatcc gcaacggcgt caactatgcg aaacaggcgc agtctgtact ccagaccact
    55861 atcagcgccg ttcgggtgac acagaaaatg aaggataacc ccgttgtcgc actgacccgt
    55921 gtgccggggc tgatgagcgg actgggtaat atctccgggg ctctggggaa aagtgttccg
    55981 gcgtttaacg cactctctga atccatgccc gatgccatca gtctggccag aacagccagc
    56041 gaagcagcca cgtatgtaca gcaggcacag tctgcgctga gtggtgtgga caaaagaaat
    56101 attgcaggtg ctctggatac cgtttccggg cagcttaacg ccgtcggcac agcattcaac
    56161 cgcatgtctc cgggattaag tgcaatggcc gccagaatac tgacgaggag tgtgtgatgt
    56221 ttcttgaaca tgttacccgt gacggagagc gctgggattc gctggcatgg cagtactacg
    56281 gtgacccgct gggctatccc cggattattg ccgccaatcc gcacgtggcc atcacgccgg
    56341 tgctgccctc cgggctgttg ttactgatcc cggtgattga ggctgaagaa gcccgtacag
    56401 aagaggatat tgccccatgg ctgagataaa cagcactgcg caagtcacat cagcgttaac
    56461 cggcgtcagc gatgtgctga caccggtgtt cactctgtgg tatctgcaga aaaacatcac
    56521 ctctgatatc gcgccttatg tcacccgtgt gacctggagc gataacatca aaaatgagtc
    56581 cgataccatt gaggtggagc tggacgacac cgatggccgc tggctggata aatggtatcc
    56641 gggcaagggt gacacgctga cgctgaaaat gggctatcag ggcgagaagc tgctgtcctg
    56701 cggtacgttc tctatagacg agatcgaagt gagttcgccc gcttccgttg tttctatccg
    56761 tggggtggcc acctcggtta acagtgccct gcggactaaa accagtcgtg gttttgagaa
    56821 caccacgctg gcagctgttg cggggcggat tgccagaaag caccggctga aactggtggg
    56881 cagcattgag tccatcagaa tcgaccgggt gacccagtat gctgaaaccg acgtgggttt
    56941 tctgcgccgg ctggccagcg agtatggtta tgcagtgaaa gtggtcagtg accagctgat
    57001 tttttctcat ctggccacac tgcgcagtca ggagccggtc aggcagttaa aaccgcagga
    57061 tgtggcccgc ttttccctgc gtgacaccat caaccgggtc tataaatctg caaaggtaaa
    57121 acaccagaaa agcagcagta aaaaactgat cgtctacgaa gctgatggtg gtacccgtga
    57181 aagcgacaaa aagctcaaag gtggtaaggt taccagcgct gactcactta aagttaacag
    57241 ccgcgtcagc gacccggaca gtgcccggat taaagcggat tcagcactgg ccagacataa
    57301 cgaataccag cagaacggct ccctgacgct gacgggaaca cctcaactga cagcaggcaa
    57361 caaaattgaa ctggtgagtt ttgggcagtt atccgggcca tggctcataa ccactgcccg
    57421 ccatgcgttt gaccgtaaca gcggctacac cacagagctg gaagtggcac gggggccagt
    57481 cacaagaggg aaaaaacaaa aaactcagaa actcacggtt tatcacccgg atggcagtac
    57541 atcgacggtg attaaggaga agaaaaaatg actggtgtca ctcgtcaggt cggtacggtc
    57601 agtgccgttg atgccgacag ggttcaggcc cgcgttcgtc tgcctgaatg cgataacctg
    57661 cgcacaaact ggcttaacgt gctgcagcgc aatacccagg ataacaaaga ttactggctc
    57721 cctgacgtgg gggagcaggt tgaggtgctg ctcgatgcca acggcgagga tggtgttatt
    57781 ctgggcgcgg tgtattcaga cgtcgataaa ccaccgttca gtgacaaaaa tatccgggga
    57841 acccggtttg ctgatggtgc agagtacagc tacaaccgga agacgcacac tctgatcatc
    57901 cggggcggca ttgagcatat tgtcattgag tgtggtgctg atgtggtatt gaaaacacag
    57961 aaagccacga ttgacgcacc ggaaaccgaa cttaccggag atctgcgtgt caggggtaag
    58021 ctgatttacg aaggaggcat ggcgggttct ggtggtgaag gtgttaccgc gaccatccat
    58081 ggcaatatcg agattaaagg gaatgtccat gccacgggca gtatgttgtc tgatggcgaa
    58141 aactccagcc accactccca ctgagctttt taaacgcctt taatatcagc gttcccgcac
    58201 gggggcaata ctgcccccat gaaaacaacc tcagtattct ggcaaccagc cctgcaggct
    58261 cccggcgaaa ttgtccgggg gctggatgat atccggcagg agattcaaat tatcctgcgg
    58321 actccccgcg gcagcgaccc gcatcgcccg gagttcggca gcaatctgca tctttatatc
    58381 gactggcctg tagaccgggc cattccgcat gtggtgcgcg aatccgtcga tgccatccgg
    58441 cgctgggagc cccgctgcca gcttatgtca gttaaacccg ccgtcgacgg cgaacatctt
    58501 acgctccggg tgagctggaa aggctcagac ggacagaccc ggactcagga gctgctatgg
    58561 cgctgacaga acccgatttt attgaacgcg atgccgacaa aatcacggca gaaatgattg
    58621 cgaagtatga agcggatacc ggcaaaacgc tgtacccggc acaggcagaa cgtctgctga
    58681 ttgatctgtg ggcctatcgc gaaatgctgg tcagggttgc ggtacaggag gcagcaaagc
    58741 agaatctggt cgcctttgcc cgtgagccga tgattgatta cctcggtgaa ctggtcggtg
    58801 tataccgtct tgccgcgcag cctgccacca ccacgctcca gttctccgta gatgaggcac
    58861 tggccattga tgtgctgatc ccggcaggca cccgcgtcag cgcttccgac agcgttattt
    58921 ttgccaccga tacagatgtg gtactgaagg ccggattgct gctggtcaat gtcacggcca
    58981 cctgtaccga acccggtacc gctggtaacg gctggcaacc tgcgcaggtc agtcagttac
    59041 tcgatgagat tgataacgtt aacctgctgg tgagcaatct gatggccagt tccggcggtt
    59101 cagaacagga agacgatgac aggctccggg agcgtatcag gctggccccg gagtcattca
    59161 ccaatgccgg aagccgtggc gcataccgct ttcatgccat gcaggcccat cccaacattg
    59221 tcgatgttgc tgtgctttcc ccggttcccg ggaccgtaga tctgtatccg ctgctcagta
    59281 ccggtctgcc ggacggcggt gttctcacgc tggtagagag tttctgctct gatgagaaag
    59341 tcaggccact cactgataca gtgcgggcta aaacaccagt gaaggtggat tacaccattg
    59401 aagccaggat tacgatctat cgtgatcagg atgccaggtc tgtaaaagat gccgctaaca
    59461 gcgccataca gaactgggtg gcatcacgtg ccgccacgct ggggcgcgat attgtcccca
    59521 gccagattat cagtgcattg tccgtttccg gggtgtacca ggttgaactg gtgacaccgg
    59581 cactgcgggt ggtggcagaa aacgaatggg caaactgtac ggcaatcact cttaacatga
    59641 ctggagtgtc tgatgactga gccattacaa ctcccgccac cgcttgaggg tgatatcagt
    59701 ctcaggacgc tgggaagact ggcaggacgg ctggataaca tcgacctgag cgtactgatg
    59761 gtctttctcg tcgatatcgt cgacagttcc gcgctgccat ggctgggcga gcagttctca
    59821 ctgtctggcg atggctggga gctggcggaa tcggacgatg ttcgccgcat gcttataaaa
    59881 gcagccatcg aactgcaccg gtataaaggg acgccgtggt caatccggga agttatccgc
    59941 cgttttggct ttggtgaagt ggatctgatt gaaggcacag gtcgtctcag ttacgacggc
    60001 aatcgcagct ataacggact gtttgttcat ggagatgcag ccgcctgggc agtttatcgc
    60061 gttattctga aacagcccat tactaacgat caggccgcga tgctgcgtca gacgctggct
    60121 gcatttgcac cggcccgctg ccatctggcc agcctggagt atcagtctgt ggccattcgc
    60181 tataacaata ccgccatcca tgatggcagt tataaccacg ggagcagttg attatgggaa
    60241 acctgaatga aacagaaaag tgggaagaaa atatctatca actggagaca tcagatccgg
    60301 ttctgggtgg tgcagacggg atatcaaatc gagccccccg gcaactggca aacaggacga
    60361 aatggctgaa gaagaaaacg gaggaagccg cacagtcact ggctgaacac gtacgttccc
    60421 gtaaccaccc ggacgcgaca ctgacagcta aggggttcac ccaactgagc agtgccacca
    60481 acagcacctc tgaaacgctg gccgccacac caaaagcggt caaggctgca tacgacctgg
    60541 cagccggcaa ggcgcctgcc agccacactc acccgtggag tcagataacg ggagtgcctg
    60601 cggcttcact gacggcaaaa ggcaccgtac aactgagcag cgccacggac agtcaatcag
    60661 aaactgaggc tgccacgccg aaggcggtca aggctgcata cgaccttgca gccggcaagg
    60721 cgcccgtcag ccacactcac ccgtggagtc agataacggg agtgcctgct gcctcgctga
    60781 cggcaaaagg caccgtacaa ttgagcagtg ccatcaacag cacgtctgaa atactggccg
    60841 ccacaccgaa agcggtcaag gctgcatacg atctggcaaa cggaaaacaa ccggcagatg
    60901 ccacgctcac tgctctggca ggacttgcca ctgcagcaga tcggttgcct tattttaccg
    60961 gagcagaccg cgcagagctg gcaaccctta cagctattgg tcgcgctatt atcgctaagg
    61021 gcagtataaa agatgtcctc aattaccttg gtttggggga aggctcggcg ctgcccgttg
    61081 gtgtacctgt tccgtggccc actgccacac cgccagcagg ctggttaaag tgcgacgggc
    61141 gcgcctttac aaaagaacaa tatcctgttc tggccagagt ctacccgacc ctccgtcttc
    61201 ccgatttacg cggtgagttt atccgtggat gggacgacgg gcgaaaagtg gatacagggc
    61261 gcgatctgct ttcacggcag gatggtacaa gtttttctca ttacgcaggt aattttgaca
    61321 ttgggtctgg tcattcaatc aataactatg accaaatcgt tgacaaccaa cctggattct
    61381 cccgtttttc atttgcaggt ccttcgcgag gcgatggggt taattatgtg accattcgtc
    61441 cccgtaacat tgcgtttaat tacatcgtaa gggcggcata gaaacgttgg tttgggggaa
    61501 ggctctgcat tgcctgttgg tgtaccggtt ccatggccca ccgccacacc gccagcaggc
    61561 tggttacagt gcaacggagc tacgttcacc aaagaacaat atcctgttct ggtcagagtc
    61621 tacccgaccc tccgtcttcc cgatttgcgc ggtgagttta tccgtggatg ggacggtggt
    61681 cgcaaggttg ataccgggcg tgcgctactt tcatttcagg aagggactat cgtatccggt
    61741 tttgatgata atgataccgg agatatcagt tcgctcggct ctacacaata cggatttggt
    61801 gacgctttaa cctctaatca actgggggtc ttaaatggca aaaagtggat atttgatgca
    61861 tcctctaaag gtgcacaaag atatgactgg tgggcttatg tatcagctcg cccccgcaat
    61921 atcgcattta actatatcgt gagggcggcg tgataccgtt cagccggcaa gcgccagtgg
    61981 cgcttccggc cagctgattt caggtgcctt gctgatatcc agtgcgttca gctcgtcgat
    62041 ataatccagc acggcgttca gttttgccgt ttcttctggt ttcagactgc gaccagcacg
    62101 cagtttgagg ttgataagat cgacggacgc catcgcctgt ttcacccgtt gctggcgttg
    62161 ctgtctggca acctccagtt ctgcggctcg ctgccgttca gtatcggtta cccacgcctc
    62221 accgttccag gtatcccatg gcgtggctgg ctgttttgtg gtggtgtccg ccgggtaatc
    62281 acccggttgg gtaatcagaa cggggttacc gttctccgtg ctgtataccg tctcgccgcg
    62341 gtgatcaggc acatgctccc acccgttcag cgtggcagtc cggcaaacca cgtaacccga
    62401 aattgcttcc ggcggtgcat cggcgcacga atgtgccgga gtacccaccc caagggcgag
    62461 atactccaca gaggatgagg tgtattcccg ggtttcctcg tcatagtgat atacagtgat
    62521 atcgcccgct acagtggcga taccgttttc atccagaact gcagtgttac tcattaaact
    62581 gccctcacaa tgtaattaag tgcaatgcta cggggtctga cagtgatacc cttcgcatac
    62641 ccgcttctga tagaggtcag aatagtagcc tgcataccat tgtctgacat tgccacgaca
    62701 ggatcgctga atgttgtccc gtccggcatt ttaaagctgc cctcacgaag gtctgtaatg
    62761 gaatcttcat tgttgaatcc catgccgact atccccgagg ttcccgtagt gtcctggtta
    62821 taataatcca gcattgctgt tcttaacagc gttgcccctt gtgcggacag caacttacgt
    62881 cctgtatcaa ctttgcgccc gtcgtcccat ccacggataa actcaccgcg taaatcggga
    62941 agacggaggg tcgggtagac tctggccaga acaggatatt gttcttttgt aaaggcgcgc
    63001 ccgtcgcact ttaaccagcc tgctggcggt gtggcggtgg gccacggaac aggcacacca
    63061 acgggtagcg ccgagccttc tcctaaacca acgtttatct ctcaaatcct ccccacatta
    63121 tctcagtact ttaaccactc aaaagggagt atttttaatg ctgattggct acatacgtgt
    63181 gtcaacaaat gaccaaaaca cagatttgca acgcaatgca ttaatgtgcg caggatgtga
    63241 acagattttt gaggacaaaa tgagcggaac caagtcggaa cgaccaggcc tga
//
LOCUS       DAFGPF010000014        62511 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFGPF010000014 DAFGPF010000000
VERSION     DAFGPF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 62511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62511
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.014"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..875
                     /locus_tag="LSX49_001088"
     CDS             <1..875
                     /locus_tag="LSX49_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7167525.1"
                     /translation="DLNLLVIFECIYQHLSISKAAESLYITPSAVSQSLQRLRAQFND
                     PLFIRSGKGIAPTTTGLNLHHHLEKNLRGLEQTINIVNKSELKKNFIIYGPQLISCTN
                     NNMLIRCLRQDTSIDIECHDILLSAENAEELLVQRKTDLAITLQPVISRSVICMPLHT
                     IRNSLICSNKHPRITDTSNYEQIIAEEFTLLISKSAGIDEIQMDIDERFINRKVSFRS
                     SSLLTIINSISVTDLLGIVPTELYDLHRDFLKLKEIKLEQPLPAVKLYISYNKASLNN
                     LVFSRFIDRLNDSF"
     gene            1022..2242
                     /locus_tag="LSX49_001089"
     CDS             1022..2242
                     /locus_tag="LSX49_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HBL7167526.1"
                     /translation="MSIYKIPLPLNILEAAKERITWTLNTLPRICVSFSGGKDSGLML
                     HLTAEIARQMGKKICVLFIDWEAQFSCTINYVQSLREFYADVIEEFYWVALPLTTQNS
                     LSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFSFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQQLCNPLYNIMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKSITVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKAKNYQRYNERI
                     KGKRKEWGILCNND"
     gene            2215..2844
                     /locus_tag="LSX49_001090"
     CDS             2215..2844
                     /locus_tag="LSX49_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBL7167527.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRINAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLKKSIEIDGFTQPIVVTHTDKNALEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQFSRAWTVK"
     gene            complement(2845..4005)
                     /gene="ybdL"
                     /locus_tag="LSX49_001091"
     CDS             complement(2845..4005)
                     /gene="ybdL"
                     /locus_tag="LSX49_001091"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HBL7167528.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTKMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAYHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDVDSNITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRIALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATVWQQTDFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTMDD
                     VEFCQWLTREHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            4114..5202
                     /gene="hcxA"
                     /locus_tag="LSX49_001092"
     CDS             4114..5202
                     /gene="hcxA"
                     /locus_tag="LSX49_001092"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HBL7167529.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGER
                     AIAAAQTKLPPAFELPGVKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQEYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALA
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQVEIDKMIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVESFKA"
     gene            complement(5212..5409)
                     /locus_tag="LSX49_001093"
     CDS             complement(5212..5409)
                     /locus_tag="LSX49_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HBL7167530.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(5522..7627)
                     /gene="cstA"
                     /locus_tag="LSX49_001094"
     CDS             complement(5522..7627)
                     /gene="cstA"
                     /locus_tag="LSX49_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HBL7167531.1"
                     /translation="MNKSGKYLVWTVLAVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFAITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGEVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKEPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(7808..8221)
                     /gene="entH"
                     /locus_tag="LSX49_001095"
     CDS             complement(7808..8221)
                     /gene="entH"
                     /locus_tag="LSX49_001095"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HBL7167532.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(8224..8970)
                     /gene="entA"
                     /locus_tag="LSX49_001096"
     CDS             complement(8224..8970)
                     /gene="entA"
                     /locus_tag="LSX49_001096"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HBL7167533.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFSQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIACPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(8970..9827)
                     /gene="entB"
                     /locus_tag="LSX49_001097"
     CDS             complement(8970..9827)
                     /gene="entB"
                     /locus_tag="LSX49_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HBL7167534.1"
                     /translation="MAIPKLQAYALPEPHDIPQNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(9841..11451)
                     /gene="entE"
                     /locus_tag="LSX49_001098"
     CDS             complement(9841..11451)
                     /gene="entE"
                     /locus_tag="LSX49_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HBL7167535.1"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GEWQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVAEHSSIRVVQLLNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALAEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRTSA"
     gene            complement(11461..12636)
                     /gene="entC"
                     /locus_tag="LSX49_001099"
     CDS             complement(11461..12636)
                     /gene="entC"
                     /locus_tag="LSX49_001099"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HBL7167536.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHLAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            12825..13781
                     /gene="fepB"
                     /locus_tag="LSX49_001100"
     CDS             12825..13781
                     /gene="fepB"
                     /locus_tag="LSX49_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL7167537.1"
                     /translation="MRLASLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIALFDKQLAAAKEQIKLPPQPVTALVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF"
     gene            complement(13785..15035)
                     /gene="entS"
                     /locus_tag="LSX49_001101"
     CDS             complement(13785..15035)
                     /gene="entS"
                     /locus_tag="LSX49_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HBL7167538.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLSVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMIGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSVRPGLLMLLSTLGAFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRRFRQTPPQVTASDN"
     gene            15146..16150
                     /gene="fepD"
                     /locus_tag="LSX49_001102"
     CDS             15146..16150
                     /gene="fepD"
                     /locus_tag="LSX49_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HBL7167539.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAL
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLMMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLTAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            16147..17139
                     /gene="fepG"
                     /locus_tag="LSX49_001103"
     CDS             16147..17139
                     /gene="fepG"
                     /locus_tag="LSX49_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HBL7167540.1"
                     /translation="MIYVSRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            17136..17951
                     /gene="fepC"
                     /locus_tag="LSX49_001104"
     CDS             17136..17951
                     /gene="fepC"
                     /locus_tag="LSX49_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HBL7167541.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEDAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTAKI"
     gene            complement(17948..19081)
                     /gene="fepE"
                     /locus_tag="LSX49_001105"
     CDS             complement(17948..19081)
                     /gene="fepE"
                     /locus_tag="LSX49_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
                     /protein_id="HBL7167542.1"
                     /translation="MSSLNIKQGSEAHFPEYPLASPSNNEIDLLNLIEVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKTFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDPLDLHRAIVALSEKMKAVDDNAS
                     KKKDESALYTSWTLSFTAPTSEEAQKVLAGYIDYISALVVKESIENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKTNVNDVNFTPFKYQLRPSLPVKKD
                     GQGKAIIVILSALVGGMVACGGVLLRHAMASRKQDAMMADHLV"
     gene            complement(19328..23209)
                     /gene="entF"
                     /locus_tag="LSX49_001106"
     CDS             complement(19328..23209)
                     /gene="entF"
                     /locus_tag="LSX49_001106"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HBL7167543.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSDLPSAWSVAHYVELTGEVDAPLL
                     ARAVVAGLAQADTLRMRFTEDNGEVWQWVDDAQTFELPEIIDLRTNIDPHGTARALMQ
                     ADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCAL
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAAQETLPQLATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGEEPLFGPVLNIKVFDYQLDIPGVQAQTHPLATGPVNDLELALFPDEHGDLSI
                     EILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQINATQI
                     EIPETTLSALVAEQAAKTPDAPALADARYQFSYREMREQVVALANLLRERGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     ADVPDLTRLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASLTPQTARQNCSTLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAEVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQTPGRVP
                     KAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQFARQVTPGQVM
                     VASTVAKLATIIDGEEDSTRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPQWSIIGIQSPRPHGPMQTAANLDEVCEAHLATLFEQQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVAFDGKATLFVAERTLQEGMSPEQAWAPWIAEL
                     DIYRQDCAHVDIISPEYFKEIGPLINTQINN"
     gene            complement(23206..23424)
                     /gene="ybdZ"
                     /locus_tag="LSX49_001107"
     CDS             complement(23206..23424)
                     /gene="ybdZ"
                     /locus_tag="LSX49_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis protein YbdZ"
                     /protein_id="HBL7167544.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCALPAGWDVVCQPQ
                     SQASCQQWLEAHWRTLTPANFTQLQEAQ"
     gene            complement(23427..24629)
                     /gene="fes"
                     /locus_tag="LSX49_001108"
     CDS             complement(23427..24629)
                     /gene="fes"
                     /locus_tag="LSX49_001108"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HBL7167545.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEGHS
                     AIKRVWVYITGMTDHHQNSQPRSMQRIAGTDVWQWTTQLNANWRGSYCFIPTERDDIF
                     SAPSPDRLELREGWRKLLPQAIADPLNPQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PETPAKEIIWKSERLKNSRRVWIFTIGDATAEERPLAVLLDGEFWAQSMPVWPALTSL
                     THRRQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPQVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGHQEGMLLEQLKTGEVSAEG
                     LRIVLEAGVREPMIMQANQALYAQLHPLKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            24667..24867
                     /locus_tag="LSX49_001109"
                     /pseudo
     CDS             24667..24867
                     /locus_tag="LSX49_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174912.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24872..27112
                     /gene="fepA"
                     /locus_tag="LSX49_001110"
     CDS             24872..27112
                     /gene="fepA"
                     /locus_tag="LSX49_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HBL7167546.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDAYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKAAQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     KNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SINTHF"
     gene            27287..27946
                     /gene="entD"
                     /locus_tag="LSX49_001111"
     CDS             27287..27946
                     /gene="entD"
                     /locus_tag="LSX49_001111"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002430230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HBL7167547.1"
                     /translation="MKTTHTSLPFAGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGR
                     KRKTEHLAGRIAAIYALREYGYKCVPAIGELRQPVWPTGVYGSISHCGTTALAVVSRQ
                     PIGIDIEEIFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKACER
                     QTDAGFLRYQIRNCQHQQMNISGPNGDHIVQWLVRGNNVITLCLADKHPHTAACGLSG
                     G"
     gene            complement(27948..28883)
                     /locus_tag="LSX49_001112"
     CDS             complement(27948..28883)
                     /locus_tag="LSX49_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003831178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBL7167548.1"
                     /translation="MRNSEHLANVMVQAFIDAVNEGIDLVPVVADSTSTAKIAPFIKQ
                     FPDRLVNVGIAEQSMVGTAAGLALGGKVAVTCNAAPFLIARANEQIKVDVCYNFTNVK
                     LFGLNAGASYGPLASTHHAIDDIAVMRGFGNIQIFAPSSPRECRQVIDYALRYQGPVY
                     IRMDGKALPEIHDEDYRFVPGAVVTLREGSELALVATGSTVHEVVDAAELLAQSGIAA
                     TVVSVPSIRPCDTKALLAALKGCKAVMTVEEHNVNGGLGSLVAEVLAEAGTGITLKRA
                     GIMDGEYAAAADRGWLRQHHGFDAAGIAAQAREML"
     gene            complement(28876..29706)
                     /locus_tag="LSX49_001113"
     CDS             complement(28876..29706)
                     /locus_tag="LSX49_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL7167549.1"
                     /translation="MNPYSYDIQTLERKARAVRRHIVRLNANSPAGGHTGADLSQVEL
                     LTALYFRILNVAPDRLHDDDRDIYIQSKGHAVGCYYCVLAEAGFFPLEWLSTYQQPNS
                     HLPGHPVRQKTPGIELNTGALGHGFPVAVGLALAAKKSQSRRRIFLITGDGELAEGSN
                     WEAALAAAHYGLDNLVIINDKNNLQLAGPTREIMNTDPLAEKWLAFGMQVTECQGNDM
                     ASVVATLEELKQEGKPNVVIAHTTKGAGISFIQGRAEWHHRVPKGDEIEQALEELKDA
                     "
     gene            30069..31019
                     /locus_tag="LSX49_001114"
     CDS             30069..31019
                     /locus_tag="LSX49_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBL7167550.1"
                     /translation="MAKQDEQRLLVKIATLYYLEGRKQSDIAQLLSLSQSFISRALTR
                     CQKEGVVKISVVQPSNIFLNLEKGIEERYGIKQAIVVDTEDDASDHTIKRAIGSAAAH
                     YLETRLRPKDFIGVSSWSSTIRAMVDEVHAQNLKASGVIQLLGGVGPNGNVQATILTQ
                     TLAQHLNCEAWLLPSQSIEGSVEEKKRLVASQDVADVIARFDDVDIAIVGIGILEPSQ
                     LLKTSGNYYHEDMLQVLADRGAVGDICLHYYDKHGQPVLQDDEDPVIGMALDKIKKCP
                     NVVALAGGKDKVAAIKGAMQGGYIDVLITDFPTARMLIAD"
     gene            31370..32890
                     /locus_tag="LSX49_001115"
     CDS             31370..32890
                     /locus_tag="LSX49_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBL7167551.1"
                     /translation="MFAGNKEFVIALDEGTTNAKAIALDGFGNVVAKFSQPLAIQTPR
                     EGWVEQSGEALISASLDVIAQAINHVGAENVAALAISNQRETAIGWYRQSGKPLNAAI
                     TWQCTRSAEFCETLRREGKEQQIKTTTGLPIAPLFSASKMRWLLESTPEGVQLADQGE
                     ICLGTIDAWLLWNLTAGDSFCCDYSNAARTQLLNLKTGEWDEEMLALFHIPRAALPEI
                     KPSSGLFGYTRGLKTIPDGIPVMAMVGDSHAALFGHALGEAGCVKATYGTGSSVMAPV
                     NSAQCDIATLATTIAWHDGENIIYGLEGNIPHTGDAVAWMADSTGLSELTDAELALEL
                     NTLPASVDSTMGVYFVPALTGLGAPWWDDSARGVVCGLSRGVKRAHLIRAALESITYQ
                     IADVVEAMQQHDDFHLSALMVDGGPTKNDWLMQYQADLLGCPVMCSDVPELSAIGAGL
                     LARKALIPGTVADLKALLTEHSEFKPDMARHQRLQKRWQEWRHAVNRTLWKPASSI"
     gene            32994..33929
                     /locus_tag="LSX49_001116"
     CDS             32994..33929
                     /locus_tag="LSX49_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7167552.1"
                     /translation="MKLRLTLLTAATLTALSFSAHAVEKGTIMIMVNSLDNPYYASEA
                     KGASEKAQQLGYKTTILSHGEDVKKQNELIDTAIGKKVQGIILDNADSTASVAAIEKA
                     KKAGIPVILINREIPVDDVALVQITHNNFQAGSEVANAFVEKMGEKGKYAELTCNLAD
                     NNCVTRSKSFHQVIDQFPEMVSVAKQDAKGTLIDGKRIMDSILQAHPDVKGVICGNGP
                     VALGAIAALKAANRNDVIVVGIDGSNDERDAVKAESLQATVMLQAQAIAAQGVTDLDN
                     YLQKGVKPAKQRVMFRGILITKDNADKVQDFNIKS"
     gene            33976..34596
                     /locus_tag="LSX49_001117"
     CDS             33976..34596
                     /locus_tag="LSX49_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004111235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2291 domain-containing protein"
                     /protein_id="HBL7167553.1"
                     /translation="MDKKVWLALAILSLGGCRIVSQQELADLKSPPNPHMANIDQTWQ
                     KNIVPQVVENARPVAELMAALQAEKDVDAACKTLGYRSQEENPCIFYVKVEGSITNID
                     AKSRSGKMTITDISGTNIVVQTGPTLRGTLLRDAYKGASYEHFNDQVLFGEYGRAINE
                     QAINMIQSAKLKTGETVQVYGVFSAWDIPQTIPDITPAKIARAGGE"
     gene            34598..36142
                     /locus_tag="LSX49_001118"
     CDS             34598..36142
                     /locus_tag="LSX49_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL7167554.1"
                     /translation="MLPQEIAPPQTDESPVIIETHDLSRIYPGVVALDNVNYRVYRNK
                     VNVLIGENGAGKSTMMKMLAGVETPSSGKIILDGKEVTLNSTHQAEKHGISIIFQELN
                     LFPNMNVMDNIFMANEFFQKGKINEKYQYELAKSLLERLELNVDPYTQLGELGIGHQQ
                     LVEIARALSKDTRVLIMDEPTSALSQSEVKVLFNVIAQLKRRGVTIIYISHRLEELME
                     IGDFITIFRDGRFISERAVSDASIPWIIEQMVGDKKKHFDYQPATQGDTVLAVQGLTA
                     LHPSGGYKLNDVTFSLHKGEVIGIYGLLGAGRTELFKGLVGLMPCQSGKIQLNGETID
                     KCHFQARLKKGLALVPEDRQGEGVVQMMSIQSNMTLSDFSLQGFRRAWKWLNPQKESA
                     SVKEMILQLAIKVSDAELPITSLSGGNQQKVVLGKALMTQPQVVFLDEPTRGIDVGAK
                     TDVYQLVGKMAQQGLAVMFSSSELDEVMALADRILVMADGRITADLPRGEVTREKLIA
                     ASTPQD"
     gene            36160..37227
                     /locus_tag="LSX49_001119"
     CDS             36160..37227
                     /locus_tag="LSX49_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7167555.1"
                     /translation="MNQKYMIYMYLLKARTFIALLLVIAFFSVMVPNFLTASNLLIMT
                     QHVAITGLLAIGMTLVILTGGIDLSVGAVAGICGMVAGALLTNGLPLWSGNIIFFNVP
                     EVILCVAVFGILVGLVNGAVITRFGVAPFICTLGMMYVARGSALLFNDGSTYPNLNGM
                     ETLGNTGFATLGSGTFLGIYLPIWLMIGFLILGYWITTKTPLGRYIYAIGGNESAARL
                     AGVPIVKVKVFVYAFSGLCAAFVGLIVASQLQTAHPMTGNMFEMDAIGATVLGGTALA
                     GGRGRVSGSIIGAFVIVFLADGMVMMGVSDFWQMVIKGLVIVTAVVVDQFQQKLQNKV
                     ILMRRHEEKMAAAPAVKPLSS"
     gene            37281..38078
                     /locus_tag="LSX49_001120"
     CDS             37281..38078
                     /locus_tag="LSX49_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7167556.1"
                     /translation="MQRNFQGKTVVITGACRGIGAGIAERFARDGANLVMVSNAERVH
                     ETAEQLRQCYQADILSLEVDVTDEAQVQALYEQAAARFGSIDVSIQNAGIITIDYFDR
                     MPAADFEKVLAVNTTAVWLCCREAAKYMVKQNHGCLINTSSGQGRQGFIYTPHYAASK
                     MGVIGITQSLVHELAQWNITVNAFCPGIIESEMWDYNDRVWGEILSTDDKRYGKGELM
                     AEWVEGIPMKRAGKPEDVAGLVAFLASDDARYLTGQTINIDGGLIMS"
     gene            38111..38896
                     /locus_tag="LSX49_001121"
     CDS             38111..38896
                     /locus_tag="LSX49_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7167557.1"
                     /translation="MIAKDFAQQLFDLHDRVAFVTGAGSGIGQMIALALASAGARVVC
                     FDLREDGGLKETVNHIEALGGQALYYTGDVRELRDLRAAVALAKTHFGRLDIAVNAAG
                     IANANPALEMESEQWQRVIDINLTGVWNSCKAEAELMVENGDGSIINIASMSGIIVNR
                     GLEQAHYNSSKAGVIHLSKSLAMEWVSKGIRVNSISPGYTATPMNTRPEMVHQTREFE
                     SQTPIQRMAKVEEMAGPALFLASDAASFCTGVDLVVDGGFVCW"
     gene            complement(39006..39158)
                     /gene="hokE"
                     /locus_tag="LSX49_001122"
     CDS             complement(39006..39158)
                     /gene="hokE"
                     /locus_tag="LSX49_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HBL7167558.1"
                     /translation="MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            complement(39508..39660)
                     /gene="hokE"
                     /locus_tag="LSX49_001123"
     CDS             complement(39508..39660)
                     /gene="hokE"
                     /locus_tag="LSX49_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HBL7167559.1"
                     /translation="MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            40103..41221
                     /locus_tag="LSX49_001124"
     CDS             40103..41221
                     /locus_tag="LSX49_001124"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HBL7167560.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDTVKNQ
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FISLSAASPYMQGTDTRFASSRPNIFSAFPDNGPMQWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRSLTEATLRLLEKIAPSAHKIGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGE"
     gene            41287..41535
                     /locus_tag="LSX49_001125"
     CDS             41287..41535
                     /locus_tag="LSX49_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 domain-containing protein"
                     /protein_id="HBL7167561.1"
                     /translation="MKHPLETLTTAAGILLMAFLSCLLLPAPALGLTLAQKLVTTFHL
                     MDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSLAD"
     gene            41600..41983
                     /locus_tag="LSX49_001126"
     CDS             41600..41983
                     /locus_tag="LSX49_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBL7167562.1"
                     /translation="MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSS
                     ELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALLRDLIND
                     SWNLVVDGLAKRDQKRLRPDSTVNQ"
     gene            42062..42715
                     /gene="nfsB"
                     /locus_tag="LSX49_001127"
     CDS             42062..42715
                     /gene="nfsB"
                     /locus_tag="LSX49_001127"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HBL7167563.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAADNYVFNERKMLDASHVVVFCAKTAMDDAWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDEEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            42823..44070
                     /gene="ybdG"
                     /locus_tag="LSX49_001128"
     CDS             42823..44070
                     /gene="ybdG"
                     /locus_tag="LSX49_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel YbdG"
                     /protein_id="HBL7167564.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(44228..45610)
                     /gene="pheP"
                     /locus_tag="LSX49_001129"
     CDS             complement(44228..45610)
                     /gene="pheP"
                     /locus_tag="LSX49_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HBL7167565.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFV
                     AFKTLRRKVN"
     gene            complement(45712..48855)
                     /gene="cusA"
                     /locus_tag="LSX49_001130"
     CDS             complement(45712..48855)
                     /gene="cusA"
                     /locus_tag="LSX49_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HBL7167566.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVSDPQRLAQYGISLADVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQVGPEMRRGIA
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKNDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQDQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDTMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(48867..50090)
                     /gene="cusB"
                     /locus_tag="LSX49_001131"
     CDS             complement(48867..50090)
                     /gene="cusB"
                     /locus_tag="LSX49_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HBL7167567.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWFAKEEPPAEKTSTAERKVLF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFSQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEIDNADEALKPGMNAGLQLNTASEPMLLIPSQALID
                     TGNEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     gene            complement(50106..50438)
                     /gene="cusF"
                     /locus_tag="LSX49_001132"
     CDS             complement(50106..50438)
                     /gene="cusF"
                     /locus_tag="LSX49_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HBL7167568.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVV
                     KGVDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(50462..51844)
                     /gene="cusC"
                     /locus_tag="LSX49_001133"
     CDS             complement(50462..51844)
                     /gene="cusC"
                     /locus_tag="LSX49_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HBL7167569.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMAALKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGDSATTRELSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDITEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGGWQQ"
     gene            52001..52684
                     /gene="cusR"
                     /locus_tag="LSX49_001134"
     CDS             52001..52684
                     /gene="cusR"
                     /locus_tag="LSX49_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HBL7167570.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            52674..54116
                     /gene="cusS"
                     /locus_tag="LSX49_001135"
     CDS             52674..54116
                     /gene="cusS"
                     /locus_tag="LSX49_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HBL7167571.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLANSHGKTVYHSP
                     GAPDIREFTRDAIPDKDAQAGEVYLLSGPTMMMPGHGHGHMEHSNWRMINLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDECQVAGDPLMLRRALSNLLSNALRYTP
                     TGETIVVRCQTVDHLVQVTVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFVIILPA"
     gene            54266..56503
                     /gene="nrfB"
                     /locus_tag="LSX49_001136"
     CDS             54266..56503
                     /gene="nrfB"
                     /locus_tag="LSX49_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HBL7167572.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYHI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMINRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRALKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLDNDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     gene            56490..59462
                     /gene="nfrA"
                     /locus_tag="LSX49_001137"
     CDS             56490..59462
                     /gene="nfrA"
                     /locus_tag="LSX49_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HBL7167573.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDDRLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAAQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLIEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAEALRLARLLYQQEPASLTRLDQLTWQLMQN
                     GQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPDAWQHRAVAYQAYQVEDYATALTAWQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEQRGLGNNALYWWLHAQRYIPGQPELALNDLTRSINIAPSANAYVARATIYRQ
                     RHNIPAAVSDLRAALELEPNNSNTQAALGYALWDSGDIAQSREMLEQAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WSFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRLGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFLAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            59463..60353
                     /locus_tag="LSX49_001138"
     CDS             59463..60353
                     /locus_tag="LSX49_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HBL7167574.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRALLFKRATAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAVPGVTPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISIFFAGNMSPDGYRQLLEQVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSSAPASGIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAQSILEY"
     gene            61001..61954
                     /gene="ompT"
                     /locus_tag="LSX49_001139"
     CDS             61001..61954
                     /gene="ompT"
                     /locus_tag="LSX49_001139"
                     /EC_number="3.4.23.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease OmpT"
                     /protein_id="HBL7167575.1"
                     /translation="MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGK
                     TKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMV
                     DQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYS
                     FTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTF
                     KYSGWVEASDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYIEGAWNRV
                     TNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF"
     gene            62186..>62511
                     /locus_tag="LSX49_001140"
     CDS             62186..>62511
                     /locus_tag="LSX49_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBL7167576.1"
                     /translation="MVKLMKKNTDDGAKIYTPLTLKLYDWWVLGVSNRLAWGCPTKEH
                     LLPHFLEHLGNNHLDIGVGTGFYLTHVPESSLISLMDLNEASLNAASTRAGESKIKHK
                     ISHDVF"
BASE COUNT        15444 a        16609 c        15740 g        14718 t
ORIGIN      
        1 ttgacctcaa tttactggtt atatttgaat gtatttatca acatctcagc attagtaaag
       61 cggcagaatc attatatata acaccctctg ctgttagtca gtcgttacaa cgtttacgtg
      121 cgcaatttaa tgacccgtta ttcattcgct cagggaaagg tatcgcgccg actacaacag
      181 ggttaaacct gcatcaccat cttgagaaaa atctcagagg ccttgaacaa acgatcaata
      241 tcgttaataa gtctgaacta aagaaaaatt ttattatcta cggtcctcag cttatttctt
      301 gtactaataa caacatgcta atccgctgtc ttagacaaga tacttcaatc gatatagaat
      361 gccatgacat actgctttca gctgaaaatg ccgaagaact gttggttcaa cgcaaaactg
      421 acctggcaat tacgctgcaa ccagtaatta gtcgctctgt catctgcatg ccgttacaca
      481 ctattcgcaa ttcccttata tgtagcaaca aacatcctcg tattactgat accagtaact
      541 atgaacaaat tatcgccgaa gaattcaccc tgttgatatc taaatcagca gggattgacg
      601 aaattcaaat ggacatagat gaacgtttta taaaccgtaa agtttcattt cgcagttctt
      661 ctttgttgac tataattaat agcatttctg ttactgactt attaggcatt gtgcccaccg
      721 aactgtacga tttacatcgt gactttttga agttaaaaga aataaaactg gaacaacctc
      781 ttcctgcggt taaactttat atttcctata acaaggcttc gttgaacaac cttgtcttct
      841 ctcgattcat agatcgttta aatgatagct tctgattcat taccactgac aaataatata
      901 ttacgcatca attaattcat tgtgtgaata taaaataatg tgctctatct tgcttcgttt
      961 atcctataat tagcggattc atctcacgag tcaccccgta acgttcagag agcgttttta
     1021 gatgtctatt tataaaatcc cgcttccact gaatattctg gaagctgcaa aagaacgtat
     1081 tacctggaca cttaataccc taccccgtat ctgtgtttct ttttcgggtg gtaaagattc
     1141 cggattaatg ctgcatctga cagctgaaat tgcccgacaa atgggcaaaa aaatctgcgt
     1201 tttgtttatc gactgggaag cgcagttctc atgcactatt aactatgttc agtcattacg
     1261 tgagttttac gccgatgtca tcgaagagtt ttactgggtt gcgctcccgc ttacgacgca
     1321 aaattccctt tctcaatacc aacccgaatg gcagtgctgg gaacctgatg tcgaatgggt
     1381 gcgtcagccc ccgcaagatg cgataaccga tcctgacttt ttctcctttt accagcctgg
     1441 catgaccttc gaacaatttg tgcgtgagtt tgctgaatgg ttttcacaaa aacgtccggc
     1501 ggcgatgatg atcggcatcc gtgcagatga gtcctacaac cgttttgtcg ccatcgccag
     1561 tttaaataaa caacgttttg ccgatgataa gccctggacc accgccgcac caggcggtca
     1621 tagctggtac atttacccca tctacgactg gaaagtggct gatatctgga cctggtatgc
     1681 taaccatcaa cagctctgta acccactgta taatataatg tatcaggcag gcgtccctct
     1741 gcgtcatatg cgaatttgcg aaccttttgg cccggagcaa cggcaaggat tatggctcta
     1801 tcacgttatc gaaccggatc gctgggctgc tatgtgcgca cgagtcagcg gggtaaaaag
     1861 tggcggcatt tacgccggac atgataatca tttttatggt catcggaaaa tcctcaagcc
     1921 agaacattta gactggcaag aatatgcatt attgctgctc aatagcatgc cggaaaaaac
     1981 agcggagcat taccgcaata aaatcgccat ttatttgcac tggtatcaga aaaaaagcat
     2041 cacggttcca caaactcagc aaggggacat tggggcgaaa gatatcccct cctggcggcg
     2101 aatatgcaaa gttttactca ataacgatta ctggtgtcgg gcattatcat ttagccctac
     2161 gaaagcgaag aactatcagc gttataacga acggataaaa ggaaaacgta aggaatgggg
     2221 gatactatgc aacaacgatt aacgcaggat ttaacccaat ttctcgccag cttgccggaa
     2281 gatgatcgca tcaacgcgat taatgaaatc cgcatggcga tccatcaggt tagccccttt
     2341 cgtgaagagc cagtggattg cgttctgtgg gttaaaaaca gccaacttat gcctaatgat
     2401 tacaacccaa acaacgtggc accacccgaa aaaaaactgc tgaaaaaatc cattgaaata
     2461 gatggtttta cccaacccat tgtggtcacg catacggata aaaatgccct ggaaatcgtg
     2521 gatggttttc accgccatga aattggtaaa ggctcatcat cgttaaaatt acgcttaaaa
     2581 ggttatttgc cggtgacctg tctggaaggt acgcgtaatc aacgcatcgc cgcgactatt
     2641 cgtcataatc gcgctcgtgg acgtcaccaa atcactgcca tgtcagaaat cgtccgagaa
     2701 ctcagccagt tgggatggga cgataataaa attggcaaag agctgggaat ggacagcgac
     2761 gaagtgttac gcctgaagca aattaacggc ctgcaagagt tgtttgccga ccgtcaattt
     2821 tcccgcgcct ggacggttaa ataactacag ctggcgcagg cgttctgctg ctgccagcaa
     2881 cgtcgattcc ttcttggcaa aacagagacg aatcagttta tgtgggaagg gatcggcgca
     2941 aaacaccgac agcggaatcg ccgctacgcc gtgctcccgc gtcagccact ggcaaaactc
     3001 aacatcatcc atcgtagata cggcgctgta atccaccagc aaaaagtatg taccttcgca
     3061 cggtaaaatc tccagccgac tttcatttaa ggcattcacc agaatatcgc gcttctggcg
     3121 ataaaagtcc ggtaatgcaa gataatgctc aggttctgca cgtagcatat cggcaagcgc
     3181 cagttgtgcc ggggtattca ccgaaaaggt cagatactga tgcactttgc ggatctcggc
     3241 gctgatgggc gcaggcgcaa cgcaataacc cactttccag ccggtcatat gataggtctt
     3301 accaaacgat gacaccgcca ccgctcgctc acgcaattgc ggatgcgcca gcacgctggc
     3361 atggccctgt tgtgaaaaat tgatgtgctc gtagacttca tcgctaatga caaaaatctc
     3421 gtgcccggcg atcgcctgcc acagagcggc gaaatcagtc tgctgccaga cagttgcact
     3481 ggggttatgc ggggtgttga ggatcaccag tcgggtgcgc tcgcttaaca atgcggcaaa
     3541 ttcctgccag tcaacgcgaa aatgcggcgg ttgcagtgca atacgtttca ctattccccc
     3601 cgaaagtgcg atggcggggg cgtaactgtc atagctggga tcaaaacaaa tcacttcgtc
     3661 gccattgcgc accaatgcgg ttatcgccgc gtataacgcc tccgtcgccc ctgccgtcac
     3721 ggtgatattg ctgtcgacat ccggttgata gccatacaga cgttccgttt tctgagcaat
     3781 cgcctcgcgc aaggcctgca cgccggtcat gggtgcgtat tggtttgccc cctgggcaac
     3841 gtggtacgcc agccgctcct gtaaatagcg cggaccatca aaatcaggaa agccttgcga
     3901 aaggttaatc gcctggtgtt gctgcgccag cgcgctcatc ttggtgaaaa tagtggtgcc
     3961 aagttgtgga agtttgcttt gtggaatcag agggttattt gtcattttta ttgtacctga
     4021 cgaagttgcg tgttgaaggc actataacac gatgctagta tttggcaatc aagacgttta
     4081 gatgtctaaa taaaacaata aggacaacac aacatgcctc acaatcctat ccgcgtggtc
     4141 gtcggcccgg ctaactactt ttcacatccc ggaagtttca atcacctgca cgattttttc
     4201 actgatgaac aactttctcg cgcggtgtgg atctacggcg aacgcgccat tgctgcggca
     4261 caaaccaaac tgccgcctgc gtttgaactg ccaggggtaa agcatatttt gtttcgtggt
     4321 cattgcagcg aaagcgacgt gcaacaactg gcggcggagt ccggtgacga tcgcagcgtg
     4381 gtgattggcg tcggcggcgg cgcactactc gacaccgcga aagccctcgc ccgccgtctc
     4441 ggtctgccgt ttgttgccgt tccgacgatc gccgctacct gcgccgcctg gacaccgctc
     4501 tccgtctggt ataacgatgc cggacaagcg ctgcattatg agattttcga cgacgccaat
     4561 tttatggtgc tggtggaacc ggagattatc ctcaatgcgc cacaagaata tctactggcg
     4621 gggatcggtg acacgctggc gaaatggtat gaagcggtgg tgctggctcc gcaaccagaa
     4681 acgttgccgc taaccgtgcg gctgggaatc aataatgcgc aggccattcg cgacgtcttg
     4741 ttaaacagta gcgaacaggc gcttgccgat cagcaaaatc agcaattaac gcaatcattt
     4801 tgcgatgtgg tggatgcgat tattgctggt ggtgggatgg tcggtggtct gggcgatcgt
     4861 tttacgcgtg tggcggcggc ccatgccgtg cataacggtc tgaccgtttt gccgcaaacc
     4921 gagaagtttc tccacggcac caaagtcgcc tacggaattc tggtgcaaag cgccttgctg
     4981 ggtcaggatg atgtgctggc gcaattaacc ggggcgtatc agcgttttca tctgccgact
     5041 acgctggcgg agctggaagt ggatatcaat aatcaggtgg agatcgacaa aatgattgcc
     5101 cacaccctac gtccggtgga atccattcat tacctgccag tcacgctgac accagatacc
     5161 ttgcgtgcag cgttcgaaaa agtggaatcg tttaaagcct gacgtacaaa tttagcagca
     5221 gcgcgcgccg ccttttccac catagcgcgc gtcctgccgc tcacggaaaa actcctcgta
     5281 ggtcatcggc gtttgatcgg gatggttaac ccgcatatgt tcgacatagt tgtcgtaatc
     5341 aggcatacca atcatcagtt tcgccgcctg acctaaatat tttccggctt ttgccagtga
     5401 atcaaacatc taaacctccg gtaatacaaa tgccctcctg aattaagagg gcttaattgc
     5461 tatcaacacg ctcgggctga gagtaagggg aacgttcagc acatcccccc tcactctgac
     5521 tttagtgcgc gcctttcgcc tgcgccacga tctcctcgac attttccggc atcggctcat
     5581 atggcgtttc tttcgccgtt ggcttcggct ctttcaatgc cgccagtgcc gtcttaatcg
     5641 agaacagcgc cagaaccacc acgaccacca taaagaagat ggttaacccg gcatcaagac
     5701 ggttgttgaa caccagttgc gccagttgtg actcagtata ctgcgatgga atattgccgc
     5761 tgtcgatcat tgcctggaac ttgttagcaa tcgccaggaa tccgactttc gcatccgggc
     5821 taaacgcttt ctgccagcct gcggtcaggg tacaaatcag cagccaggcc gttggtacca
     5881 gcgccaccca ggcgtaacgt tgacgtttca ttttgaacag caccacagca caaagcatca
     5941 gcgccatccc tgccagcatc tggttggcaa taccaaacag cggccacaag gtgttaatac
     6001 cgcccagcgg atcgacctcg ccctgatgca ggaagtagcc ccacgccagc acgcacagcg
     6061 ccgttgccag caggttagca ggcagtgaat cggtccgttt caggcccgga gacaccacgc
     6121 ccagcagatc ctgcaacata aagcgcgcag cacgcgtacc cgcatccacc gccgtcagaa
     6181 taaacagtgc ttcaaacaga atggcgaagt gataccagaa cgccacatcc atcatgccgc
     6241 ccagcgcacc gtgcagaatg taggccatcc ccaccgccag ggtcggcgca ccgcccgcac
     6301 gggaaatgat cgactgttca cccacttcgc tggcaatctg gtttagcgta tccggggtaa
     6361 tcgcaaagcc ccagctactc accacctgcg cggcagaagc aaccacatcc gccgtccctg
     6421 ccggagccag caccgccatc gggctgttca tggcgaagta cacacccgga tcgatgatac
     6481 aggcggaaac cagtgccata atcgccacaa aggattccat taacatcccg ccgtagccga
     6541 taaagcacgc ctgcccttcg ttcgccagca tcttcggcgt ggtgccggaa gagatcagcg
     6601 catggaagcc agacaccgcg ccacaggcga tggtgataaa caggaacggg aacaggttac
     6661 cggtccatac cgggccagtg ccatcgacaa atttagttag cgcaggcatg gtcagcgtcg
     6721 ggcgcataat taaaatgccc accgccagac cgacgatagt cccgattttc aggaaggttg
     6781 agaggtagtc acgcggagcc agcagcaacc acaccggcag caccgccgcc acaaaaccgt
     6841 agcccaccag catccaggtc agctgcacgc cggtaaagtc aaagtacggt gcccaggtcg
     6901 ggctttctgc cacccagccg ccagagataa tggcgaaaat caggaacacc agaccaatta
     6961 ccgacacttc gccaatacgc cccggacgca aatagcgcag gtagatcccc ataaacagcg
     7021 ccagcggaat ggtgaacgca acggtatacg ttccccacgg gctatgagtc agggctttca
     7081 ccacaatcat cgccagcacg gcaaggataa tgaccatgat cataaagcag gccaccagcg
     7141 ctatcacccc ggcggttggt cccatctctt ctttgaccag ctcacccagc gagcgaccgt
     7201 cacggcgcgt agaaacaaac agcaccatga aatcctgcac cgcaccggcg agaaccaccc
     7261 cggcgagcag ccagatcatc cctggcaggt aacccatttg cgccgccagt accggcccaa
     7321 ccaacggacc tgctccggca atggccgcaa aatggtgacc gaacagcact tttttgtccg
     7381 tcggcacata gtccagcccg tcgttatggc gcaccgctgg cgtcatacgc gtcgggtcaa
     7441 ccgccagcac atttttggcg atatacaggc cataaaaacg gtaggcgatt agatagatac
     7501 agaccgacgc caccacaatc cacagcgcgt tgatctgttc cccacgattt aaagcaatgt
     7561 atcccagagc aaatgctccc attacagcga gcactgtcca gacgaggtat ttccctgatt
     7621 tgttcatagt tgttatccgt gtgcgtgtcc atagagatgt tacattttgt ttctataaca
     7681 tctttgtaca atttaacaac acagcaacca tgtaaatcgg aattgaaacc aatatttaac
     7741 ttaacaatgt taactcgatc actccgttaa ccgagttttc ctgcaatctc atttaattct
     7801 gtcgggctca tcccaaaact gccgtaccca gccgacaggt gcagcagcgc cgcccctgtt
     7861 catcgaaaac gacaatttcc cagctctgat tttgtcgtcc aagatgcagc ggctggcaga
     7921 caccgcgcac ctttccctca gacaccgggc gatgatgtgt ggcgttaagt tccgtgccca
     7981 ccacacactg tccgtcgcgg gtcatcataa atccggccat cgatcccagc gtttccgcca
     8041 gcgccgccga cgcgccgcca tgcagcaggc caaacggctg atgagtacgg gtatcaaccg
     8101 gcatttcggc ttcgagtaca tcatcgccca gacgggtata cacaattccc agatgcgcca
     8161 ccattgtgtt atcgctggtg gcgttcagct cgtcgagcgt taaatgacgt ttccagatca
     8221 tgcttatgcc cccagcgttg agccgccatc gaccacaata tcctgtaggg taatatggct
     8281 ggcgaggtca gaggcgagga acaaaatcgt gttggcgatc tcttgtggac aggcgatttt
     8341 ccctagcgga atgccgagtt taaactgctc gccaaagccg cgaatacgct gctcttcggc
     8401 gtcatcgctc acccacagcg tgcgttgcat atcggtgtcg gtggagcccg gcgaaaccac
     8461 attacagcgc acgccgctac ccgccagttc cagcccgacg ctcaacgcca ggcttttcag
     8521 cgccgctttc gacgcgccat aagcactcat accaatacgc ggcgtgtgtg cggcgtcgga
     8581 cgcaacagta acaatcgccc cgccccgctg acggcgaaac tggttcatgg tctgctgaaa
     8641 caggttaaac gcaccgccga cgttgaccgc aaaagtctgc tgccagtcct ctttactgag
     8701 ctgatcggtc gcgcccatgc gcaaaattcc cgccgcattg accagcacgt ccagtcgctc
     8761 cgtttcagct aacagtcgct gacatacctg cgccacctgc gcagcatcgg caacatccat
     8821 tacttcggtc gcaaaaggat attgctcctg actaaacgct tgatcaaaac ctgtaacttt
     8881 cgcccccgcc tcaacaaatg ccagcgccgt ggcgtagcct atacctttcc ccgcgccagt
     8941 tacccagaca tttttaccgc tgaaatccat tatttcacct cgcgggagag tagcttccac
     9001 caggcgtcga tggtcgggtt tttcgccagc atgacaaagt cgatatcgcc atgcactttg
     9061 cgccagcgcg ccgccagcgc catcatgcgc accgaatcca gaccgtagtc gatcaggttg
     9121 tcgtcatcga agggttcatc ggactcgtcc agcaacggca ggatcacctc acgcagcgcc
     9181 gctttgctgg cggggatagg tgctggcagc aattcttcgg tcatcaccac ccgaccagaa
     9241 cgtccggcca catatttcag cgacatcaaa tgctcgtcac ggctgaaatc ggccagcgca
     9301 tccgccacca taaacggttt aatatcgcgc ataaatgcgt ccgttgcggt ggtcatacag
     9361 ccaatgtggg catatacccc ggtaataatc agctggttac gtccactctc tttgagcatt
     9421 tgctccagcg gagaacgatg aaatgcgctg tagcgccatt tcaccagcac cgtgtcgtcg
     9481 gcatctggcg tcaggcgatc caccaccttt tgctgttccg gcgaacgggt caggccaggc
     9541 ccccacatat cattcaacag cgcccgatct tcatcgctct gctctttcgg ctgggcggtg
     9601 taataaaccg ggatattgtg ctgtttgcag tagtcgcgta gtgccgcaat attcgcgatc
     9661 acctgctcca tcatcgggca gttctcaccc cagaagctga caaaatagtc ctgcatatca
     9721 tggattaaca acgcggcacg ttgcggttca aaggcccagt cgactttatt ctgcggaata
     9781 tcgtgaggct ccggcagtgc gtaagcctgt aattttggaa tagccatcgt gttctctcct
     9841 tcaggctgat gtgcgtgacg ccagccactg acgtaattgt tttttatcga ctttcccgac
     9901 cgccgtcagc ggaagtgaat ctacacactc cacgcgatcc ggtaatttaa attcggcaat
     9961 accctgttca cgcaggaaac gacgcacctg caccgcgcgc agcggctctt ttaccaccag
    10021 ataagcacag cttttttcgc ccatcagctc atcttccatg ctcaccagtg cggcgtagat
    10081 caccgccgga tggcgcagca gcaggttttc gatctcttcg gcagcgatct tctcgccgcc
    10141 acggttgatc tgatctttct cgcgcccctg cacagtgatg taaccctctg gatcaataga
    10201 gatcagatcg ccggaacagt aaaaaccgtt ggcatcaaag gcgctggcat tgtgctgcgg
    10261 gcttttgtaa tagccacgga aagtgtacgg cccgcgcgtc atcaggcgtc caacttcccc
    10321 ttgcggcagt ggatttcctt cggcatcggc aacccatact tcatcgtccg ggcacattgg
    10381 gtaaccctgg gtatggataa ttttctccgc actatcatca agacgggtgt agttcaccag
    10441 cccttccgcc atgccaaaca cctgctgcaa ctggcagcca atctcagcgg gaatacgcgc
    10501 cgcaagcgtg gcagaaagac gtgcgccgcc gacctgtaac agtttcagcg aggcaagctg
    10561 cgcccggctt tcgccttcag ccagtgcctg caaccacagg ctgactgctg gcggcaccag
    10621 cgcggtgacg ttcacctgat gtttttcaat caatgggaag caaagcgtgg cgctggggtc
    10681 ggcagccaga acgacagtgc cgccagcgag aaataccccc aacgatcccg gtgaactcat
    10741 ggcgtagtta tgagccgccg ggatcgcgca caggtagcgc gtctgttgtg tgaactgaca
    10801 aatctcgacg ctacgacgca cgctgtagta gtagtcgtta tgagtgcgcg ggatcagttt
    10861 cggagtgccg gtggtgccgc cggaaagctg gaaataggcc acttcatcag caggagatgg
    10921 cgtggcagta aaatcctcag ccggatggtt aatcgcatcc tgcaagttat gctcaccgct
    10981 gtcgttgagc agctgcacca cgcgaatgga agaatgctct gcaacaaatg tgttgaggaa
    11041 atcatccccg ctaaatagcg catgttggcg atcggcaatc agtaacgccg gttcaatctg
    11101 gctggcatag gcgttcagtt cactacgctg atggctgaac agcgccagca ccggcgcaac
    11161 gcccagtttc agcagcgcga aaaaggtaat gtaaagttca gcgacgttac ccagttgtac
    11221 cagcgcggtt tcaccaggtt taatgccctg acggcgcaaa ctacaggcga ggttatccgc
    11281 cgcctgattc agctcccggt aactcaactg ccactcgccg tcgatcaccg cgatgctgtc
    11341 actcgcagcg tggcgagtca gaatgtcggt cagtggcaaa tcctgccagt agcctttttc
    11401 ccgatagcga cgggcaaact cttccggcca tcgggtgaat ggaatgctca tcctcgctcc
    11461 ttaatgcaat ccaaaaacgt tcaacatggt agaaagtttg acgcctgttt cgcgccactc
    11521 acccaacggt gaggacgcag gcacaatccc cgctccggca aacagacgca cctgattttc
    11581 ccgcagcttc gcgcagcgga tggtcaccac ccattcaccg ttaccttcgc tgtcacacca
    11641 acccacaatg ccgccaaaca gttcgcggtc gaacggctcc agttcagcaa taacctgagt
    11701 cgcggccaga tgcgggaaac cgctcagcgc aggagttgga tgcagcagac aggccagagt
    11761 cagtgcgttt tcttgcgaat tcgctttacc ttcaaaggga gttgcgagat gccacagcgt
    11821 cggcgtggta atcaattgtg gagaggaggg aacgtgtaac tcactactgc gttcgcgcag
    11881 tacctctttc atcgcctgag tcaccagttc atgttcatgg cgatcttttt ctgacgccag
    11941 cagacgatta cccgcttcgc gatcgagcac ttcatctggc tgacgacgcg cggaaccggc
    12001 taacggaatg gagctaaaac gctcgccgtc tttacgtagc agcagttccg ggctggcccc
    12061 cagcagaacg ccaccatcag ccaacggaac atggaagttg taactaaccg ggttttgcgc
    12121 aatcaaccgt tccagcaata cgccactatc aatggcggcg tcagtggtga tatcaatcaa
    12181 ccgtgacaac accactttgt cgacctgcgg cgtggcggta agtgcggcag cacgggcaac
    12241 catctgttca aacgtggttt gttccggaat ggcctgacgt tccaccacgt tcagcgactg
    12301 gctgcgggtg aaacggcgtg cggaagcttg tttttcctga cgggagaacg actgccagga
    12361 ttcgggaata tacagcgacg aaggctgacg tggatcgaag ggaatcgccc cgaccatcac
    12421 cggatttttg atgccctgcg ctttggcatc ggcaaacagc gcggcgagtt tttgctggaa
    12481 gggactgtcg ggtgaatccc cgttcacagc gggttcatcg aagcgggcga aacatcctga
    12541 cgtcgtaaaa ctgcggtacg gcgacataaa gaaaaagcga ttgggcgcaa gtgttgccat
    12601 ggtctgctgt acttcctcag ccagtgacgt atccatatca tcctccacaa aatgataaag
    12661 gctttaataa tgattatcat ttatattttc ggtcgctaac ctaaaagcaa acgcgcacta
    12721 tgtcaactct tgaggtaacg caatctgcaa ctcggggttg catctggttg tggttacaat
    12781 gaaaatgaga agcattaact tcattaataa caggaagctg atttgtgaga ctcgcctcgc
    12841 tctaccgcaa cgcccttcta ttaacaggac ttttgctttc aggaatagcc gcagttcagg
    12901 ccgccgactg gccgcgtcag attactgaca gccgtggcac tcataccctg gaaagccagc
    12961 cgcagcgtat tgtatccacc agcgtcaccc tgactggctc actgctggcg attgatgctc
    13021 cggtgatcgc cagcggcgcg accacaccaa ataaccgcgt agcggatgac cagggctttt
    13081 tacgccagtg gagcaaggtg gcgaaagaac gcaaactgca acggctctat atcggcgaac
    13141 cgagtgcaga agccgttgcc gcgcaaatgc cggatctgat tttaattagc gcaaccggcg
    13201 gcgattcggc gctggcgctg tacgatcagc tttctaccat cgccccaaca ttaatcatca
    13261 attacgacga caaaagctgg cagtcgctgt taacgcagct tggcgaaatt accgggcatg
    13321 agaaacaagc ggcagagcgg attgcactgt ttgataagca actggcagcg gcgaaagagc
    13381 aaatcaaatt accgccgcag ccggtcactg cccttgtcta taccgccgct gcacacagtg
    13441 ccaatctctg gacgccggaa tcagcacaag ggcagatgct ggaacaactc ggctttacgc
    13501 tggcgaagtt gcccgcaggc ttaaacgcca gccaaagcca gggcaaacgc catgacatca
    13561 ttcagcttgg tggagaaaat ctggctgcag ggttaaatgg cgagtcacta ttcctgttcg
    13621 ccggtgatca gaaagacgcc gatgctattt atgctaatcc gctgctcgcg cacctgcctg
    13681 cagtacaaaa caagcaggtt tatgcgctgg gaaccgagac attccgcctg gattactaca
    13741 gcgccatgca agtgctggaa cgacttaagg cgctgtttta agcattaatt gtcggacgct
    13801 gtcacctgcg gcggcgtctg gcgaaaacgc cgcaactcca ccagcaccag caacaacaac
    13861 acgccgataa tcaacaaacc aaaaccgctc gcgcttgcgg aagcaaccgg tgtcatcatc
    13921 gctcccagac cgcctaacag cgccgcacct atggcatcgc ccgtcacgtt ttgcgccgtc
    13981 cacaaaccgt taatccgccc taacatcgct tccggggttt gcgtttgcag cattgtatat
    14041 tgcagcaacg aactaaccgc gctcagccag ccgaacagtg ccagacaaac cacgcctaaa
    14101 atccacatcg gcatcaggcc aaacagacca atggcgagga acgcccccaa tgtggagagc
    14161 aacatcaaca gacctggccg tacgctatgc gccagttttc cactggttaa cgcgccaata
    14221 gccgcaccga gcgggattgc cgcatagaga aagccaattt gcgccgccga catctgccag
    14281 ttgtcagcca gcgccggata cagtacccgc accgcgctcg ccatcgtcaa taaacccccc
    14341 agcaacgcaa tccctcccac cagcgggctg gcgagtagaa aacgaaatcc tgccagtaat
    14401 gatttcaacg gatgctcacg cggctgcggc ggtggtggca acgccggaag gcttaacaac
    14461 ggtagcaagg taataaacgt gcccgccgcc gccagcccgt agttccaggc tacgcctccg
    14521 gtcgccagca gtaaaccacc aatcatgggc gaaatcaccg accccagacg cacagtcaac
    14581 atggtgatcg ccccggcctg cattaggttt tcacgtccta ccagtgcagg tgtcgccgcc
    14641 agtagcgccg taacgccaag tgatgcgaaa aaaccatccc ataaaccaag taaatagatt
    14701 gccagcaaag acggctccgg cagcagcgca ttcaggcaca gtccaatgaa gccaatgcca
    14761 caggtgccgc gcgccagcaa aatcactttt ttgcgctcat agcgatccgc cagcacacca
    14821 ccgatcatca gaccgacaaa catagcaccg ccggtcagcg tcaccgaaag ccccacctgc
    14881 caggtagaat gtgtcatcat ctggatctgc accggcaccg cgacgctgag caaacccaga
    14941 gacacaattg agataaaacg agcgaggaat actgcgcgaa acgccgggtg cgtttttaac
    15001 aggctgaggt taagcagcca ggattgttta ttcattacaa tgccttgcca tcaaatattt
    15061 taaataccta ttcttaggct gcacatgcta acatatccaa ataagatcga taacgataat
    15121 taatttcatt atcatggaag ttcgtatgtc tggttctgtt gccgtgacac gcgccattgc
    15181 cgtgcccgga ttgctgttat tactgattat cgcgacggca ttaagcctgc tcattggagc
    15241 aaaatcactc cccgcttccg tagtgctgga agccctctcc ggcacctgcc agagcgccga
    15301 ctgcaccatc gtgctcgacg cacgactgcc gcgcaccctt gccggtttac tggcaggcgg
    15361 tgcgcttggc cttgccgggg cgttaatgca aaccctcacc cgaaacccac ttgccgaccc
    15421 cggcttgctt ggcgtgaatg ccggagccag ctttgccatt gtgctgggtg cggcgctgtt
    15481 tggttactct tccgcgcagg aacaactgat gatggccttc gccggcgcgc tggtggcgtc
    15541 attgattgtt gcctttaccg gcagccaggg cggcgggcag ttaagtccgg tgcgtttaac
    15601 cctggcgggc gtggcgctgg cggcggtgct ggaaggactg accagcggca tcgccctgct
    15661 taatcctgac gtctacgatc aactgcgttt ctggcaagcc ggttcgctgg atattcgcaa
    15721 tctacatacc ttaaaagtgg tgctgatccc ggtgcttacc gccggagcaa ccgcgctatt
    15781 actgagccgc gcgctgaaca gtttaagcct tggcagtgac accgcgacgg cgctgggcag
    15841 tcgcgtagcg cgcacacagt tgattggtct gctggcaatt accgtgcttt gtggtagtgc
    15901 aacggcggta gttggcccga ttgcctttat tggcctgatg atgccgcaca tggcgcgctg
    15961 gctggtaggt gccgatcatc gctggtcgct gcccgtcacg ctactcgcta cccctgccct
    16021 gctgctgttt gccgatatca ttgggcgggt gattgttccc ggcgaactgc gcgtttctgt
    16081 agtcagtgcc tttattggtg caccagtgct gatcttcctc gtacgacgta aaacgcgagg
    16141 tggcgcatga tttacgtctc tcgccgatta attatcacct gtctactgtt gctaatagct
    16201 tgtgtaatgg caggcgtgtg gggattacgc agcggtgccg tcacgctgga aacctcgcag
    16261 gtattcgccg cgctgatggg cgatgcgccg cgcagtatga cgatggtggt caccgaatgg
    16321 cgtttaccac gcgtgctgat ggcgctgttg attggcgcgg cgctgggcgt cagcggcgcg
    16381 atttttcagt cgctgatgcg taacccgctc ggcagccctg acgtaatggg ctttaacacc
    16441 ggggcgtgga gcggcgtgct ggtggcgatg gtgctgtttg gtcaggatct gacggctatc
    16501 gcgctggcag caatggcggg gggtattgtc acctcgctgc tggtctggct gctcgcctgg
    16561 cgtaacggta tcgacacctt tcggttgatt attatcggta tcggcgttcg cgccatgctg
    16621 gtggccttta atacctggct gttgctgaaa gcgtctttag aaacggcgct aacagcgggt
    16681 ttgtggaatg ccggatcgct caatggcctg acgtgggcaa aaacctcacc ttccgcaccc
    16741 atcattatat taatgttaat tgccgccgcc ttgctggtgc ggcgaatgcg cttgctggaa
    16801 atgggcgatg ataccgcgtg tgcgctgggc gtcagcgtcg aacgttcgcg gctgttaatg
    16861 atgctggtcg ccgtagtgct taccgcagct gccactgccc tggcggggcc aatttccttt
    16921 attgctttag tcgcgccaca cattgcccgc cgcatcagtg gcaccgctcg ctgggggctg
    16981 acccaggcgg cgctgtgcgg ggcactttta ctgctggcgg ccgatctctg cgcccaacaa
    17041 ctgtttatgc cgtatcaact tccggttggc gtcgttaccg tcagcctcgg cggtatttac
    17101 cttatcgtct tgttaattca ggagtctcgc aaaaaatgac cgaatcagta gcccgtttgc
    17161 gtggcgaaca gttaaccctc ggatatggca aatataccgt tgcggaaaat ctgactgtag
    17221 aaatacctga tggtcacttc acggcaatta tcgggccaaa tggctgcggt aaatccacgt
    17281 tactgcgtac cttaagccgc ctgatgacgc ctgctcacgg gcatgtctgg ctggatggcg
    17341 agcacattca acattacgcc agtaaagagg ttgcacgccg gattggtctg ttggcgcaaa
    17401 atgctaccac accgggcgat atcaccgtgc aggagctggt ggcgcgtggg cgttacccgc
    17461 atcaaccgct gtttacccgc tggcgcaaag aagatgaaga cgcggtaaca aaagcgatgc
    17521 aggccacggg aataactcat ctggcggatc aaagcgtgga caccctttct ggcggacaac
    17581 gccagcgagc gtggatcgcg atggtgctgg cccaggaaac ggcaattatg ctgctcgacg
    17641 aacccacgac ctggctggat atcagtcatc agattgatct actggaactg ttaagcgaac
    17701 tgaaccgcga gaaaggctat accctggcgg cggtgctgca cgatcttaat caggcctgtc
    17761 gttacgccag ccatttgatt gcattgcggg aagggaaaat tgttgctcag ggagcgccga
    17821 aagagattgt cactgctgaa ctgatcgagc gcatttatgg tctgcgctgc atgataattg
    17881 acgatccggt tgccggaacg ccgctcgtgg tgccgctcgg acgaacggca ccttcaaccg
    17941 caaagattta aactaagtgg tctgccatca tggcatcctg ttttctggat gccatcgcat
    18001 gacgcaacaa cacaccacca caagccacca tcccgccgac caacgcagaa aggatcacga
    18061 taatcgcctt accctgaccg tcttttttta cgggtaatga cggacgcaac tgatatttaa
    18121 acggtgtaaa attcacatcg ttgacatttg tttttgttaa ttgctcgact agatactgac
    18181 gattacgtaa ttcaccgttc aattccgcaa cgtcagtgac tgctttttca atttccagtt
    18241 tgcgttcaat accgtctgca ccgagagaaa tagagaaatc ggggtcatct ttaacggcct
    18301 gaccattact gtatacgggc tttttaattc ctgccgcgtt ggcaatgtca agtgaataat
    18361 tgaggcgctg aatgtttgca tcaagttgat ttttcgtttt aatgcgatcc tgagccagtt
    18421 tttctttttc aaactgggtt ttgatctcca gtttattacg gacgttttct atcgactctt
    18481 tcaccaccaa cgcagagata taatcgatat acccggccaa cactttctgt gcctcttcac
    18541 tggtgggtgc ggtgaaactt agcgtccagg aagtatacaa tgcagactca tcttttttct
    18601 tactggcatt gtcatcaacc gctttcattt tttcgctcaa tgcaacaatg gcgcgatgca
    18661 gatccagtgg gtcgattttc gcttctttta attgatccat cacataaggt gatgaacgca
    18721 ggtactcctc aagcaagcta acagactgaa atttcttgat aaacaggtta aatgcttctg
    18781 tacgatcaat tttgatatcc agatccagca cacgaagctt agtgaatgtt ttctccagct
    18841 cttgccactg aacaggttct ggaggcgtga caaccgccgc gctagtccat ttttgcggca
    18901 ggatgaaaga gatcagcaag cctgcgcagg caaacgcaaa aacgaccgcc atgaccgttt
    18961 tttttgcccg ccataaaacc tcgattagat taagtaaatc aatttcatta ttactgggcg
    19021 acgccagagg atactcggga aaatgagctt cacttccctg tttaatattc agtgatgaca
    19081 tgtagtgaaa cctgaggttt tagtccgtaa agcacaacga tgtacatagc attctaacag
    19141 gaactgagat ttatccgaaa gcactctttc actattatta ttctcaaaat gaataacaaa
    19201 cttagcaacc ccagcaatga cgctgctctc agaaaaataa ataaatttta agaataaaaa
    19261 aaccataatc atttagtcgg attatggttt taaatgaggt tatggcaagt tctttactaa
    19321 cgtacggtta gttattaatt tgtgtattta ttagtggtcc tatttcttta aaatactccg
    19381 gggaaataat atccacatgc gcacaatcct gacgatagat atccagctca gcaatccacg
    19441 gtgcccaggc ctgttcagga ctcatacctt cctgaagcgt gcgttcggca acaaatagcg
    19501 tcgctttacc atcaaacgct acgctatgag ctgtcgtcag caggcgcaca gcatcagcgt
    19561 agttgccttc aatggtggta aacaactccg ttgaagtact tccctgctgt gccgccagga
    19621 aggcttcgcg ctcgcggtta atctccgcca gcacttccgg gtccagacca ttggcttctt
    19681 tttcctgcca gttttgcgtt tctggcggcc aggtatccag caagccaaga aatgccacct
    19741 gttcgccacg ggcacgcagt cgcgccgcaa tgccctgcgc cagcgtaccg ccaagtgaat
    19801 aacccagcag gtaataaggg ccgtgcggtt gttgttcaaa taacgttgcc agatgcgctt
    19861 cgcagacttc atccaggttt gccgccgtct gcatggggcc atgagggcgc ggcgactgaa
    19921 tgccgataat cgaccattgt ggatcgagat aacgcgagag cacgctgaac tgccaggcaa
    19981 aaccggatgc cggatggaaa caaaacagcg tcgggccatt accttcacgc aacggcagaa
    20041 tggtttcgaa tcccatgcgt cgggtgctgt cttcttcacc atcaataatc gttgccagtt
    20101 tggcgacagt tgacgcgacc atcacctgcc ccggcgtcac ctgacgggca aactgtcgac
    20161 ttaactgcgc tgccagtttc attgccagta gcgaatgacc gccaagcgca aagaaatcag
    20221 catcggcatc ctgcacgtca caacccagca acgacgagaa tgccgcggcg ataatcgttt
    20281 cactgcccgc tttcggcaca cgccccggcg tttgtgcctt cagttcaggc aacggtaagg
    20341 ctttgcgatc cagcttgccg ttggcgctaa gtggtaactg tggaagttgc agcagaacca
    20401 ccggtaccat atgtggtggc aatgtttctc gaagctgcgc ctgtaatgcg ctggtatcca
    20461 acggcagacc tgattgcgac accagatagc ccaccaactg acgcgcatca ccaccagtgg
    20521 ctgccgcctg gttaatcaca caggcgtggg taacggcttg ttcgacatcc ggcagcgcct
    20581 gcatcacgcg atcaatttcg cccagttcga tacgctgccc gcgaattttt agctgatcgt
    20641 cactgcgccc gaggtactcc actgcgccgt tatccagcca gcgggcaacg tctccggtac
    20701 ggtacatccg ttcacctggg gcaaaaggat cggcaataaa gcggctggcg gtcagatcgg
    20761 gtcgtccaag atacccctgc gccagttgaa taccggtgag atagagatcg cccgccacac
    20821 ccggcggcac cggatgcatc atcgcatcga gaatgcgcag gcccgtattc cacaccggat
    20881 aaccaatcgg cacactgctg ccgcgcacct ctgccagttc ctcgccaaaa gccggatacc
    20941 aactgacatc taccgccgct tccgtcgggc catatagatt atgcaacggc gcgccggtta
    21001 actgttgcca ttcgcggcat aaatcagccg gtagggcttc accactacag aaaacctgtt
    21061 tcaacgtcga gcaattctga cgagcggttt gcggcgtcag cgatgcaaca aatgctgcca
    21121 gcatcgacgg cacaaagtgc gtggtcgtta caccatattc ggcaaagaat tgctgcatag
    21181 cgagcgggtc gcggtgcgct tccggttcag ccatcaccag tttagccccg gcaataaacg
    21241 gccagaaaaa ctcccacacc gagacatcaa aactgcacgg cgttttttgg gcaacgacat
    21301 cttcgcctgt aagcgggtag tggttttgca tccaaagcag gcggttaacg atagccgtct
    21361 gcccgaccat tacccctttc ggcctgccgg tggagccaga ggtaaagatg atataagccg
    21421 tgtggtgcgg ttgtgaaagc tgcagcggcg cactgccctg cggtgtaagc ggggcgttat
    21481 agcaaaggcg ggttaaatct ggaacatcgg caaagcgcgg cagttgatcg tcagtggtga
    21541 ttaacagcga cggacgcgca tcttccagca tcattttcag gcgatcgtcc ggatagccgg
    21601 tatccagcgg taaccaggcc gcaccagcct caacaattgc atgtagcgcg agagtcaaaa
    21661 agaccgagcg cggtagagcc accgccacgc tgtcgcccgg tttaacgccg cgctcacgca
    21721 gcagattcgc cagcgccacc acctgctcgc gcatttcccg atagctgaac tggtaacgcg
    21781 catctgccag cgccggagca tccggtgttt ttgccgcttg ttctgccacc agcgcgctca
    21841 gcgtggtttc tggaatctca atctgagtgg cgttgatctg cgccagctgc gcatactcac
    21901 ctggcagcat aatatcgaca tcgccgcaca acagcgccgg atccgcggcg aactgggcaa
    21961 tcagcatttt caggcgttca gcgtgttgaa ttaacgttgg ctcatcgtaa cgctgtttat
    22021 tggcgaggat ttcaatactc aaatctccgt gttcatccgg gaacagggcc agttcaaggt
    22081 cattaaccgg accggttgcc aggggatggg tttgcgcctg aacaccagga atatccagtt
    22141 ggtaatcaaa taccttgata ttgagtaccg gaccgaacag cggttcctct cctgccgctc
    22201 gcccactgtc acggacaatt tgttcggcgt cgtagcgttg atggcggcgc atttttttca
    22261 gttgtgctgc cagtcgggtt gccagttgcg gcagcgtttc ttgcgccgca atgtgaatac
    22321 ccaacggtaa aacgttgagc acgggtccgg tagccgtcag cgccgccgag cccagtcgac
    22381 gcataaagat aaatccggca gcgtagtcca tgcggttgca caatcgcccc agccacaagg
    22441 ctgccaacgc aagtgctaaa tcggtacgct gcacacctga aagttgcgta gccagctggc
    22501 ggaattcccc gtcggtaaat tccagtttca ggcgcaaaat atctgccgaa gcgctgcgcc
    22561 ccggtaaagg tgccggagaa agtgacgcgg gcggtggcag ttgacgacgc tgttccgccc
    22621 agaatgccgc atcacgctgc caggcttcac tttcgcggta ctgctgatac tcttccacta
    22681 catcagcgaa aggcgtaaac ggcgaagcag gcgttggttc gccacgcagc aatgcgcagt
    22741 aaatattggc gatctggcgt gtaatggccg ggaaactgaa gccatcgacc agcaaatggt
    22801 gataacgctg ataccagtac cagcggttat ccgccacctg tatcagctga tgaaagacca
    22861 gtggtttacc actatcgacg cgcagatctt gttgcaaatc cgcctgcatt aatgcccgcg
    22921 cagtaccgtg cggatcaatg ttggttcgca ggtcgataat ttctggcagt tcgaacgtct
    22981 gcgcatcatc gacccactgc cagacttcgc cgttatcttc cgtaaaacgc atccgcaacg
    23041 tatctgcttg cgctagtccg gcaaccaccg cgcgggccag tagtggcgca tcaacctctc
    23101 cggttaactc aacgtaatgc gccacgctcc aggcggaggg taaatccgac agtttttctg
    23161 ccatccagat gccgggctgt gcggcgacca aaggtaaatg ctggctcatt gtgcctcctg
    23221 caactgggtg aaattcgccg gtgtcagagt acgccagtgg gcttccagcc actgctggca
    23281 ggacgcctgt gactgcggct gacacacaac gtcccagcct gccggtaagg cgcattgttg
    23341 cggccacaga ctgaattgcc cctgcgcatt gcgcaaaatg taaaacgctc cctgtggatc
    23401 atcgaaggga ttactgaatg ccatattcaa ctcctgtcat ggaaaagtgg ttgccagagg
    23461 tcgattagcc cctgcatcaa gccaccgcgc caacaaagcg catcatgtcc gccgtcaacc
    23521 tgacgccaga aaatggattc ttttaggggg tgtaattgcg catacagcgc ctgattggcc
    23581 tgcatgatca tcggctcgcg aacacccgct tccagcacaa tgcgcagacc ttcggcgcta
    23641 acttcaccag tttttagctg ttcaagtaac atgccctctt ggtgcccgcc ccgatgcggc
    23701 caccagtacg aacctgactg gcttaataca cagccaaagc gttcaggcca gtgcagtccg
    23761 gcatacagcg cggaaagccc accaaaactc tgtccggcga ccacggtgcg atcggcgcga
    23821 tcgctaaaag gggcaatagc tttcacctgg ggtaataact cttgctgtac tgccagccag
    23881 aaatccgcat tacacggcag ttcgtgggcg cggtgcgtgg tgtcgatagc gtcgatcaac
    23941 acatacacgg cgggcggaag ttgccgacga tgggtcagcg aagtcagcgc aggccagacg
    24001 ggcatactct gcgcccaaaa ttcgccatca agcaaaactg ccagcgggcg ttcttctgct
    24061 gttgcatcgc cgatggtaaa aatccataca cggcgtgaat ttttcaaccg ttcacttttc
    24121 cagataattt ctttggcagg cgtttctggc gcttgcggac aatcccatcc cggttgcaga
    24181 ggcgcttgcg gcatttcgag tgcagaaaca gcgtgccctc gcccgccttt ccagctttgt
    24241 ggattcagcg gatcggctat cgcctggggt aatagttttc gccagccttc gcgtaattcg
    24301 aggcgatcgg gggatggtgc agaaaaaatg tcatcgcgtt cggtaggaat aaagcagtag
    24361 ctgccgcgcc agttggcatt gagttgtgtc gtccactgcc aaacatcggt tcctgcaatt
    24421 cgctgcatcg accggggctg gctgttctga tggtgatcgg tcatgccagt gatatagacc
    24481 catacgcgct ttatcgccga gtggccttca gaaccttgtg gatcacgcca ccaaaaagtg
    24541 acttcaaaca tttcgtcatt cagacgttgc cattccgggc catgtttcga ctgccaccag
    24601 ctctcacttc ctacttttaa cgccgtcaca ccataacccc atgtttactg tgcaattttt
    24661 tattgattgc agaaatatat tgataatatt attgataact atttgcattt gcaatagcgt
    24721 aatggcgcgc cgtgggaagc gcggacatta attaatcagc tgcactgcgt gtctttcagg
    24781 atcaaaggtt ttcgcggtag cgggatgcgt cgtgttgatg acgaccatgc ccgacagttg
    24841 caattcgtgg caaaaatgca ggaataaaac aatgaacaag aagattcatt ccctggcctt
    24901 gttggtcaat ctggggattt atggggtagc acaggcacaa gagccgaccg atactcctgt
    24961 ttcacatgac gatactattg ttgttaccgc cgccgagcag aacttgcagg cgcccggcgt
    25021 ttcgaccatt accgcagatg aaatccgcaa aaacccggtt gcccgcgatg tatcggagat
    25081 cattcgtacc atgcctggcg ttaacctgac cggtaattcc accagtggtc agcgtggtaa
    25141 taaccgccag attgatattc gcggcatggg tccggaaaac acgctgattt tgattgacgg
    25201 caagccggta agcagccgta actctgtgcg tcagggctgg cgtggcgagc gcgatacccg
    25261 tggtgatacc tcctgggtgc cgcctgaaat gattgaacgt attgaagttc tacgtggtcc
    25321 ggcagctgcg cgttatggca acggcgcggc gggcggcgtg gttaacatca ttaccaaaaa
    25381 aggcagcggt gagtggcacg gctcctggga tgcttatttc aatgcgccag aacataaaga
    25441 ggaaggtgcc accaaacgca ccaacttcag cctgaccggt ccgctgggcg acgaattcag
    25501 cttccgcttg tatggcaacc tcgacaaaac ccaggctgac gcgtgggata tcaaccaggg
    25561 ccatcagtcc gcgcgtgccg gaacgtatgc cacgacgtta ccagccgggc gcgaaggggt
    25621 gatcaataaa gatattaacg gcgtggtgcg ctgggacttc gcgcctctgc aatcactcga
    25681 actggaagcg ggctacagcc gccagggtaa cctgtatgcg ggtgatacgc agaacaccaa
    25741 ctctgacgct tacactcgct cgaaatatgg cgatgaaacc aaccgcctgt atcgccagaa
    25801 ctactcgctg acctggaacg gcggctggga taacggcgtg accaccagca actgggtgca
    25861 gtacgaacac acccgtaact cgcgtattcc ggaaggtctg gcgggcggta ccgaagggaa
    25921 atttaacgaa aaagcggcac aggattttgt cgatatcgat cttgatgacg tgatgctgca
    25981 cagcgaagtt aacctgccga ttgatttcct cgtaaaccaa acgctgacgc tgggtacaga
    26041 gtggaatcag caacggatga aggacttgag ttccaacacc caggcactca ccggaacgaa
    26101 taccggcggt gctattgatg gtgtgagtgc caccgaccgt agcccatatt caaaagcaga
    26161 aattttctcg ctgtttgccg aaaacaatat ggagctgact gacagcacca tcgtaacgcc
    26221 ggggctgcgt ttcgatcatc acagtattgt cggcaataac tggagcccgg cgctgaacat
    26281 atcgcaaggt ttaggcgatg acttcacgct gaaaatgggc atcgcccgcg cctataaagc
    26341 gccgagcctg taccagacta acccaaacta cattctctac agtaaaggtc agggctgcta
    26401 tgccagcgcg ggcggctgct atctgcaagg taacgatgac ctgaaagcag aaaccagcat
    26461 caacaaggag attggtctgg agttcaaacg cgacggttgg ctggcgggcg tgacctggtt
    26521 ccgtaacgat tatcgcaata agattgaagc gggctatgta gctgtaggga aaaacgcagt
    26581 cggcaccgat ctctatcagt gggataacgt gccgaaagcg gtggttgaag gtctggaagg
    26641 atcgttaaac gtaccggtta gcgaaacggt gatgtggacc aataacatca cttatatgct
    26701 gaagagtgaa aacaaaacca cgggcgaccg tttgtcgatc atcccggagt atacgttgaa
    26761 ctcaacgctg agctggcagg cacgggaaga tttgtcgatg caaacgacct tcacctggta
    26821 cggcaaacag cagccgaaga agtacaacta taaaggtcag ccagcggttg gaccggaaac
    26881 caaagaaatc agtccgtaca gcattgttgg cctgagcgcg acctgggatg tgaccaagaa
    26941 tgtcagtctg accggcggcg tggacaacct gttcgacaaa cgtttgtggc gtgcgggtaa
    27001 tgcccagacc acgggcgatc tggcaggagc caactatatc gcaggtgccg gggcgtatac
    27061 ctataacgag ccgggacgta cgtggtatat gagcattaat actcacttct gaagctaacg
    27121 tcagattgtt gacaaagtgc gcgtagttca tgccggatgc ggcgtgaacg ccttatccgg
    27181 cctacaaaaa tcttgccaat tcaatatatt gcaggaccac gtaggcctga taagcgtagc
    27241 gcatcaggca gttttgcgtt tgtcatcatt ctctaatatg gttgacatga aaactacgca
    27301 tacctccctc ccctttgccg gacatacgct gcattttgtt gagttcgatc cggcgagttt
    27361 tcgcgagcag gatttactct ggctgccgca ctacgcacaa cttcaacacg ctggacgtaa
    27421 acgtaaaaca gagcatttag ccgggcggat cgctgcaatt tatgcgctgc gggaatatgg
    27481 ctataaatgt gtgcctgcaa tcggcgagct acgccaacct gtgtggccta cgggggtata
    27541 cggcagcatt agtcactgtg ggactacggc attagccgtg gtatctcgtc aaccgattgg
    27601 cattgatatc gaagagattt tctctgtaca aaccgcaaga gaattgacag acaacattat
    27661 tacaccagca gaacacgagc gactcgcaga atgcggttta accttttctc tggcgctgac
    27721 actggcattt tccgccaaag agagcgcatt taaggcatgt gaaagacaaa ctgatgcagg
    27781 atttctgcgc taccaaatca gaaattgtca gcatcaacag atgaatataa gcgggccgaa
    27841 tggcgaccat atcgtgcagt ggttagtaag gggtaataat gttattacct tgtgcctggc
    27901 agataaacac ccgcacactg cagcatgcgg gttatctggc gggtaattca aagcatttcc
    27961 cgtgcctgag ctgcaattcc ggcagcatca aatccatgat gctgacgcaa ccacccacga
    28021 tccgccgctg cggcatattc tccatccata atgcctgcgc gttttaatgt gatccccgtt
    28081 ccggcctctg ccaacacttc cgcgaccagg ctaccaaggc cgccattgac gttatgctct
    28141 tcaaccgtca tcactgcttt gcatcctttt aacgctgcca gcaatgcttt ggtgtcgcat
    28201 gggcgaatcg acggtacgct gacaactgta gccgcgatac cagactgcgc taaaagttct
    28261 gcggcatcga ccacttcatg aacggtagag cctgtggcta ccagcgccag ttcgctgccc
    28321 tcgcgcaaag tcaccacggc acctggtaca aatcggtagt cctcatcgtg gatttccggc
    28381 agggctttac cgtccatacg gatataaaca ggcccctgat agcgaagagc ataatcaatc
    28441 acctgacggc actcccgcgg tgaagacggg gcaaagattt gaatattgcc gaaaccacgc
    28501 ataaccgcaa tgtcatcaat cgcatgatgc gtgctcgcca gcggtccata actcgccccg
    28561 gcattcagac cgaacaattt tacgttggta aagttgtagc agacatcaac cttgatttgc
    28621 tcgttagcgc gagcgataag aaacggcgcg gcattgcagg taacagccac cttgccgccc
    28681 agcgccagcc cggcagctgt accaaccatg ctctgttcgg caatacccac attcaccagt
    28741 cggtcaggga attgcttaat aaagggagca atttttgccg tagacgttga atcagccacc
    28801 acaggcacca aatcgatccc ctcatttacg gcatcgataa acgcctgaac catcacattt
    28861 gccagatgtt cactgttacg catctttgag ttcctccagt gcctgttcaa tttcatcgcc
    28921 tttcggcacc cggtgatgcc attccgcacg cccttgtata aaggaaatgc ctgccccttt
    28981 agtggtgtgg gcaatcacca cattcggttt gccttcctgt ttaagctctt caagcgtcgc
    29041 gacaaccgaa gccatatcat tgccctgaca ttcagtaacc tgcataccga atgccagcca
    29101 tttctctgcc agaggatcgg tgttcatgat ttcgcgcgtt ggcccggcta attgcagatt
    29161 atttttgtca ttaataatga ccaggttatc aagcccgtaa tgcgccgccg ccagtgcagc
    29221 ttcccagtta ctgccctcag ccagctcacc atcgccagta attaagaaga tacgacgacg
    29281 gctttgactt tttttcgccg ccagcgcaag tcctacagcc acagggaaac catgccccag
    29341 tgctccggta ttcagttcaa tacctggcgt tttttgccga accggatggc cgggtaagtg
    29401 tgaatttggc tgctgataag tggaaagcca ttccagtggg aagaatcctg cttccgccag
    29461 cacgcagtag taacatccaa cagcatggcc ttttgactga atgtatatat cccggtcatc
    29521 gtcgtgaagg cgatccggtg cgacattgag aatacgaaaa tagagtgcgg tcagtaattc
    29581 aacctgagag agatcggccc cggtgtgtcc acctgccggg ctattggcat ttaagcgcac
    29641 gatatggcgg cgtaccgccc gcgctttacg ctcaagggtc tggatatcat agctataggg
    29701 attcatttaa tacctctgaa tttattttca acatggaata tttattccac cggggactaa
    29761 aaaaaccaga aatcccaggg cgttgcgcgg caagacttac gctgctgcat catactcagg
    29821 aacattctgc ctccttacac cgtcagttac atgtccgggt aatcatcagt tgacctgata
    29881 tcatcttgaa tatatattca ataatgattc tttattcaat tatgccgcct gttttttatt
    29941 tttgtccatc gctgatttta aggattggtt aaagttagaa ctccatcaca cttaactgtc
    30001 ttcttttttc gcgtatgata aaagcctcta agataagggc ggtacgttaa tgatttacgg
    30061 ggaaatatat ggctaagcag gatgaacagc ggctactggt gaagatcgcc actctttact
    30121 atcttgaggg gcgaaaacag tctgacatcg cccaacttct ctcgctttct cagtcattta
    30181 tatccagagc gctaacccgt tgccagaaag aaggcgtggt taaaatcagc gttgtccagc
    30241 cgtcaaatat ctttctcaat ctggaaaaag gcattgaaga gcgttacggc attaaacaag
    30301 cgattgttgt cgataccgaa gatgatgcca gtgatcacac cattaaacgc gccatcggct
    30361 ctgccgccgc gcactatctg gaaacgcgtt taaggccaaa agatttcatt ggcgtctctt
    30421 cgtggagttc tacgattcgc gcgatggtcg atgaagttca cgcccaaaac ttaaaagcca
    30481 gcggcgttat tcagctgctg ggcggcgtgg ggccaaacgg caatgtgcag gcaactattt
    30541 tgacacagac cctggcccag catctgaatt gcgaagcctg gttgcttcct tctcaaagca
    30601 ttgaaggttc ggtagaagag aaaaaacgcc tggtggcaag ccaggatgtg gctgacgtta
    30661 tcgccagatt tgacgacgtc gatatcgcca ttgtcggcat cggtatcctt gaaccctcgc
    30721 agttgctaaa aacctcgggc aactattatc acgaggatat gttacaggta ctagcggatc
    30781 gcggtgctgt gggcgatatc tgcctgcact actacgataa acatggtcag cccgtgttgc
    30841 aggacgatga agatccagtg attggtatgg cactggataa aatcaaaaaa tgcccgaatg
    30901 tggtggcact ggcgggcggc aaagacaaag ttgccgccat caaaggcgcc atgcagggtg
    30961 gttatattga tgttttgatc actgatttcc ccaccgccag aatgctgatt gcggattaat
    31021 cctctcctcc ctttcttctg cccgcctttg cgaaaaaatc ttctcgcaaa ggtgattgct
    31081 taaaaagcct ttaatatcaa taaactgaaa ggattcaaca atcctgtttc tcgaggcttt
    31141 ctcaccctgt caccacgctt ctaagtgtga tagccagcac atttgatgat tttttctcta
    31201 gctcaggaag aataatctgg ctaaggtata aataaataat cagtatcgaa tatatattca
    31261 tgccttaaca caaaatgtca cagcagggcc tgatgaagta ataacgtgac catgaggaac
    31321 gcctcatctc cttccacgcc aggatgcaat gtgactcagg agactaccta tgtttgcagg
    31381 aaataaagag ttcgttattg cgttggatga gggtaccacc aatgcaaaag ccatcgcact
    31441 tgatggtttc ggtaacgtgg tggcgaagtt ttctcaacca ctggctattc agacgccacg
    31501 tgaaggctgg gttgagcaat ccggggaagc gttaatctct gcctcgcttg atgttattgc
    31561 ccaggccatc aaccacgtgg gggcagaaaa tgtagcggct ctggctatca gtaatcagcg
    31621 tgaaacggct atcggctggt atcgtcagag tggaaaacca ctcaatgcgg cgattacctg
    31681 gcaatgcacg cgcagtgccg agttttgtga aacactgcgt cgcgagggca aagagcagca
    31741 aattaaaacg actacgggtc ttcctatcgc cccgctattt tccgcgtcca agatgcgttg
    31801 gctactggaa tctacacctg agggtgtgca acttgccgac cagggtgaaa tttgtctcgg
    31861 caccattgat gcctggttgc tatggaactt gactgctggc gattcatttt gctgcgacta
    31921 ctctaacgcc gcgcgaactc aattacttaa cctgaaaaca ggcgagtggg atgaggaaat
    31981 gctggcgttg tttcacattc cacgcgctgc attgccagaa attaaacctt ccagtggcct
    32041 gttcggttat acccgagggc ttaaaacaat tccggatggt attcccgtca tggcgatggt
    32101 gggcgattct cacgccgctc tttttggtca tgcgttggga gaagcgggat gtgtgaaagc
    32161 gacctatggg accggttctt ccgtcatggc ccccgtcaac tctgctcagt gtgatatcgc
    32221 cacacttgcc acaaccattg cctggcatga tggcgaaaat attatttacg gtctggaagg
    32281 aaatatcccc cacaccggcg atgccgtggc atggatggct gacagcaccg gtttaagtga
    32341 actgacagac gcggagctgg ccctcgaact gaataccctg ccagcctcag tggattcgac
    32401 tatgggtgtt tattttgttc ctgctctcac tggcctgggc gcgccatggt gggatgacag
    32461 cgctcgcggc gtggtgtgtg gcttaagccg tggcgtaaag cgcgcgcatt tgattcgtgc
    32521 cgcactggaa tcaatcactt atcaaattgc agatgtagtg gaggcaatgc aacagcatga
    32581 tgattttcac ttatcggcgt taatggtgga tggcggcccg accaaaaatg actggttgat
    32641 gcaatatcag gcggatctgc tgggttgccc ggtgatgtgc agtgatgtgc cagagctttc
    32701 agccattggt gcgggcctgc tcgcccgcaa agcgcttatc cccggtaccg ttgcagattt
    32761 aaaagcgtta ttaactgaac acagtgaatt taaaccggac atggcgcgtc atcagcgact
    32821 gcaaaagaga tggcaggagt ggcgtcatgc ggtaaacaga acattatgga aaccggcatc
    32881 gtcaatttga cgaacaagac taaccaacgt aaggagaata ccggcccata aataattcag
    32941 gctttacgtt gtttcaccgt acccgacaat aacaacacag agagaacatt gtcatgaaat
    33001 tacgtttaac actgttaacc gctgcgaccc tgactgctct ttctttttct gctcatgcgg
    33061 tagaaaaagg aaccattatg attatggtca attcactgga taatccttat tacgcctcgg
    33121 aagcgaaagg tgccagtgaa aaagcccagc aactgggata taaaacgacc attctttctc
    33181 atggtgaaga tgtcaaaaaa cagaatgaac tgatcgatac tgcaattggt aaaaaagttc
    33241 agggcattat tttagataat gccgactcca ctgccagtgt tgcagccatt gaaaaagcaa
    33301 aaaaagcagg tattcccgtt atattaatta atcgcgaaat acctgtggat gatgttgcac
    33361 tggtgcaaat tacccataat aacttccagg ctggctcgga agttgccaac gcatttgtcg
    33421 agaaaatggg agagaaagga aaatatgccg aactcacctg taatcttgct gataataatt
    33481 gcgtaactcg ctcgaaatct ttccaccagg ttattgacca gttccctgaa atggtcagcg
    33541 tggcgaagca agatgccaaa ggcacgttaa ttgatggcaa acgaataatg gacagtattc
    33601 tgcaagccca tcccgatgtt aaaggggtga tttgtggtaa tggtccggtt gcactgggag
    33661 ctatcgcagc actgaaagcc gccaatcgca atgacgttat tgttgtcggc attgatggca
    33721 gtaacgatga gcgcgatgcc gtgaaagccg aatcattgca ggctaccgtg atgttacaag
    33781 cacaagccat tgccgcgcag ggtgttaccg atctggataa ttacctgcaa aaaggagtta
    33841 aaccagccaa acagcgggtg atgttccgcg gcattctgat aaccaaagat aacgcagata
    33901 aagtccagga tttcaatatc aaatcctgat cccaggtcgt tgcgccctca caatgagggc
    33961 gcagaggaga atattatgga taaaaaagtc tggctggcgc tggcaattct gagcctgggt
    34021 ggatgtcgca tcgtctcgca gcaggaactt gccgatctca aatccccgcc taatcctcat
    34081 atggcaaata tcgatcagac ctggcagaaa aacatcgtgc cgcaggtggt agaaaatgcg
    34141 cgtccggttg cggagttaat ggcggcgcta caggcagaaa aagatgtcga tgctgcctgt
    34201 aaaacgctgg gctatcgttc tcaggaagaa aacccgtgta ttttctacgt taaggtcgaa
    34261 ggtagcatca ccaatattga tgcgaaatcc cgtagcggaa aaatgaccat cacagatatc
    34321 agcggcacaa atattgtcgt gcagacgggg ccaactcttc gcggcacgct tctgcgagat
    34381 gcatataaag gtgcaagcta tgagcatttt aacgatcagg ttttatttgg tgaatatggt
    34441 cgtgctatca atgagcaagc catcaatatg attcagtcgg caaagcttaa aaccggggaa
    34501 acggttcagg tttatggcgt attttctgca tgggatattc cgcaaactat cccggatata
    34561 acgcctgcga aaatagccag ggcgggaggc gagtaatatg ttgccgcaag aaattgcccc
    34621 cccccagact gatgaatcac ctgtaatcat agaaacgcat gacttatcgc gtatttatcc
    34681 gggtgtggtg gcgttagata acgtgaatta ccgagtctat cgcaataaag taaatgtgct
    34741 tattggtgaa aacggtgcgg gtaaatccac aatgatgaaa atgctggcgg gggttgaaac
    34801 accttcctca ggcaagatca ttcttgatgg taaagaagtc accctaaatt ctacccatca
    34861 ggccgaaaaa catggaatta gtatcatttt tcaggagctg aatttattcc cgaatatgaa
    34921 tgtcatggat aatattttca tggcgaatga attttttcag aaagggaaga ttaacgaaaa
    34981 atatcaatat gaattagcca aatctctatt agaaagactg gaactgaatg ttgatcccta
    35041 tacccaactg ggagagctag gtattggcca tcagcaactg gtggagattg cccgtgccct
    35101 ttctaaagat acccgggtac tgattatgga tgaaccgaca tcggccctca gccagtcgga
    35161 agtaaaagtc cttttcaatg tgatcgcaca actgaagcgc cgtggtgtca ccatcattta
    35221 tatctcccat cgtctggaag agttgatgga gattggcgat ttcatcacca ttttccgtga
    35281 tggtcgcttt attagtgaac gcgccgtgag cgatgccagt attccatgga tcatcgagca
    35341 aatggtcggt gataagaaaa aacatttcga ttatcaacca gctacacaag gtgacactgt
    35401 actggcggta caagggttaa cggcgctgca tcccagcggt ggttacaaac tcaatgatgt
    35461 gacattcagc ctgcataaag gcgaagttat cggcatttac ggcttgctgg gcgcaggacg
    35521 tactgaacta tttaagggat tggtgggcct gatgccctgt cagagtggga agatccagct
    35581 taatggtgaa accatcgaca aatgccattt ccaggcgcgg ctcaaaaagg ggctggcgtt
    35641 ggtgccagaa gatcgccagg gcgaaggcgt cgttcagatg atgtcgattc agtccaatat
    35701 gacgctatcc gatttcagcc tgcaaggttt tcgccgtgcc tggaaatggc tgaatccgca
    35761 aaaagagagc gccagtgtga aagagatgat cctgcaactg gcgatcaaag tcagcgatgc
    35821 cgaactccct attacctcac tcagcggcgg taaccagcaa aaagtggtac ttggcaaagc
    35881 gttgatgacc cagccacagg tggtgtttct tgatgaaccc acacgcggca ttgatgttgg
    35941 cgcaaaaaca gatgtctatc agctggtggg aaaaatggca caacaggggc tggcagtcat
    36001 gttctcttct tcagaactcg atgaagtcat ggcactggca gatcgcattc tggtgatggc
    36061 tgatggccgt attaccgctg atctcccccg gggcgaagtc acccgagaga aactgattgc
    36121 ggcttcaaca cctcaagatt aatcaggctg gaatttctta tgaatcagaa atatatgatc
    36181 tatatgtacc tgttgaaggc cagaacgttt atcgctctgc tattagtgat cgccttcttt
    36241 agcgtgatgg tgcctaactt cctgacagcc tctaacctgt tgatcatgac tcaacacgtt
    36301 gcgattaccg ggctgctggc aatcggaatg acgctggtga tcctgaccgg cggcatcgat
    36361 ctttccgtcg gcgcggtagc ggggatctgc ggaatggttg ccggggctct tctaacaaac
    36421 ggcctgccat tgtggagcgg caatattatt ttcttcaacg tgccggaagt gatcctctgc
    36481 gtggcggtat ttggcatttt agtgggactg gtgaatggcg cggtaatcac ccgctttggt
    36541 gtcgcgccct ttatctgcac cctcggtatg atgtacgtcg ctcgtggctc tgccctgctg
    36601 tttaatgacg gcagcactta tcccaatctc aacggcatgg aaacgctggg caacacgggt
    36661 ttcgccaccc ttggttctgg cacgttttta ggcatttatc taccaatctg gctgatgatt
    36721 ggctttttga ttttaggcta ctggatcacg actaaaacgc cgctcggtcg ttatatctat
    36781 gccattggtg gcaatgaatc tgccgcgcga ctggcaggcg tccccatcgt aaaagttaaa
    36841 gtgttcgtct atgcgttctc cgggttatgc gccgcatttg tcggtttgat tgttgcctcg
    36901 cagctgcaaa ctgctcaccc aatgaccggc aatatgttcg aaatggatgc tattggcgcc
    36961 acggttcttg gtggaactgc actggcgggt ggtcggggac gtgtctctgg ctcgattatc
    37021 ggtgcctttg tcattgtctt cctcgccgat ggcatggtga tgatgggtgt cagtgacttc
    37081 tggcaaatgg tcattaaagg cctcgttatc gtcaccgccg tggtggtcga tcagttccag
    37141 caaaaattgc aaaacaaagt cattttgatg cgtcgccatg aagaaaagat ggccgccgca
    37201 cctgccgtaa aaccgctttc cagttaatta acatcattcc accgggcatt aaattgcccg
    37261 gcttatacag gggaaaaaat atgcaacgta attttcaggg taagactgta gttattaccg
    37321 gggcatgccg gggaattggg gccgggatcg ctgaacgctt cgcccgcgat ggcgcaaatc
    37381 tggtgatggt ttctaacgct gaacgcgtac atgaaactgc agagcaactg cgccaatgtt
    37441 atcaggctga cattttgtca ttagaagtcg atgtgacaga tgaagcgcaa gtacaggcac
    37501 tctatgaaca agcggctgca cgttttggca gcatcgatgt ttccattcag aatgcaggca
    37561 ttatcaccat cgattatttt gatcgaatgc cggctgctga tttcgaaaaa gtgctggcgg
    37621 tgaacactac ggcagtctgg ctctgctgcc gggaagcagc caaatatatg gtgaaacaga
    37681 atcacggctg cctgatcaac acctcttctg gccagggacg tcaggggttt atctataccc
    37741 cacactatgc agccagcaaa atgggtgtga tcggcattac gcaaagcctg gtgcacgagt
    37801 tagcgcagtg gaatatcact gttaacgcct tctgcccggg tattatcgaa agcgaaatgt
    37861 gggactacaa cgaccgcgta tggggagaaa ttctcagtac cgatgacaag cgttatggca
    37921 aaggcgagct tatggcggaa tgggtggaag gtattccgat gaagcgtgcc ggtaaacctg
    37981 aagatgttgc cggactggtt gccttcctcg cctctgacga tgcgcgttat ctcaccggtc
    38041 aaaccatcaa catcgacggc ggcctgatta tgtcgtaatg cccctgcggg ctactaagag
    38101 agatatcaaa atgatcgcaa aagattttgc tcaacaattg tttgatctcc acgatcgcgt
    38161 cgcctttgtc actggcgcag gtagcggtat cggacaaatg atcgctctgg ctttagccag
    38221 cgcaggcgca cgagtggtgt gttttgatct acgggaagat ggcggactca aagagacggt
    38281 taatcatatc gaagcacttg gcggacaagc cttgtattac acgggcgatg ttcgggaatt
    38341 gagagatctt cgcgcagcag tcgctctggc aaaaacacat tttggtcgtc tggatattgc
    38401 cgtaaacgcc gctggaatcg ctaacgcaaa cccggcgctg gagatggaaa gcgagcaatg
    38461 gcaacgcgtt atcgatatca acctgactgg tgtgtggaat tcctgtaagg cggaagctga
    38521 gttaatggta gagaacggag acggttcgat tataaatatt gcgtcaatgt ccgggattat
    38581 tgtcaatcgt ggtctggaac aggcccacta caacagttcc aaagccggcg tgattcattt
    38641 atctaaaagt cttgcgatgg aatgggtgag taaggggatc cgcgtgaact caatcagccc
    38701 aggatatacc gcgacaccaa tgaatacacg acctgaaatg gtacatcaga ctcgggagtt
    38761 tgaaagccag acgccgattc aacggatggc gaaagtggaa gagatggcgg gtccagcgct
    38821 gttccttgcc agcgatgcgg cgtcgttctg cacgggtgtg gatctggtgg tcgatggtgg
    38881 ctttgtctgc tggtaaaaat ggtttcgccc gcagccatca ctgaccgcgg gcgaaagtgt
    38941 aaagcaggtg ccttaccacc ctgacctgac aaccggatat gcggggattg ctccccgcac
    39001 aacggctact tcttcggttc gtaagcgaga acagccttaa actcaatatt acgttccttt
    39061 acggtaaact cacacagcga gtctccgacc agaagcgtaa atcccagcac cgtcaaacac
    39121 agcactatga ctgccacaag ggcatatttc gtcagcatgt ttatattgcc tccatgcgaa
    39181 gaagggacta ccatccaaat tgtctggttt ggagtggcag ccccagggtt gatagaaata
    39241 actcctgggg cttcatcttt ccagacctca aagttaacct gaaaccggaa agcttcaggc
    39301 acccgccgtt atcttaccct tcctcaacaa aatagctgtt tatttataca gtaagtcctg
    39361 tttcggactt ctgttggcaa aactgatcat tgcccttaaa acgacatcgc ccgcagccat
    39421 cactgaccgc gggcgaaagt gtaaagcagg tgccttacca ccctgacctg acaaccggat
    39481 atgcggggat tactccccgc acaacggcta cttcttcggt tcgtaagcga gaacagcctt
    39541 aaactcaata ttacgttcct tcaccgtaaa ctcacacagc gagtctccga ccagaagcgt
    39601 aaatcccagc accgtcaaac acagcactat gactgccgca agggcatatt tcgtcagcat
    39661 gtttatattg cctccatgcg aagaagggac taccatccaa attgttcagg tttgggtagg
    39721 tagccccagg gttgatagaa atatcgtcct ggggcttcat ctttccagac ctcagagtaa
    39781 acctgaaacc ggaaagcttc aggcacccgc agttatctta cccttcctca acaaaatagc
    39841 tgtttattta tacagtaaat cctgtttcgg acttctcact ccccatttaa tcaactgaag
    39901 ctgaacccgt ttttttctgc atgcctcaat cgtcaaaatt cttcgccgcc agccagctct
    39961 gccataactt gtcacattgc aaaatgtagc caatttgctt cagtcaccat caccaaaaaa
    40021 agaaacattc cagaacttcc gcatctcgcc cagccgctcc cacttctata ctgaatagaa
    40081 aacgccaaca taagagaaac ctatgccatt acccgatttt catgtttctg aaccttttac
    40141 cctcggtatt gaactggaaa tgcaggtggt taatccgccg ggctatgact taagccagga
    40201 ctcatcaatg ctgattgaca cggttaaaaa tcagatcacg gccggagagg taaagcacga
    40261 tatcaccgaa agtatgctgg agctggcgac ggatgtttgc cgtgatatca accaggctgc
    40321 cgggcaattt tcagcgatgc agaaagtcgt attgcaggca gcggcagacc atcatctgga
    40381 aatttgcggc ggtggcacgc atccgtttca gaaatggcag cgtcaggagg tatgcgataa
    40441 cgaacgctat caacgaacgc tggaaaactt tggctatctc atccagcagg cgaccgtttt
    40501 tggtcagcat gtccatgttg gctgcgccag tggcgatgac gccatttatt tgctgcacgg
    40561 cttgtcacgg tttgtgccgc actttatctc cctttccgcc gcgtcgccat atatgcaagg
    40621 aacggatacg cgttttgcct cttcacgacc gaatattttt tccgcctttc ccgataatgg
    40681 cccgatgcag tgggtcagta actggcaaca atttgaagcc ctgtttcgct gcctgagtta
    40741 caccacgatg atcgacagca ttaaagatct gcactgggat attcgcccca gcccccattt
    40801 tggtacggtg gaagttcggg tgatggatac cccgttaacc cttagccacg cggtaaatat
    40861 ggcgggatta attcaggcta ccgcccactg gttactgacg gaacgcccgt ttaaacatca
    40921 ggagaaagat tacctgctgt ataaattcaa ccgtttccag gcctgtcgct atgggctgga
    40981 aggtgtcatt accgatccgc atactggcga tcgtcggtca ctaacggaag ccaccttgcg
    41041 tttactggaa aaaatcgccc cttctgcaca taaaattggc gcatcgagcg caattgaagc
    41101 actgcaccgt caggtcgtca gtggtctgaa tgaagcgcag ctaatgcgtg atttcgtcgc
    41161 cgatggtggc tcgctaattg ggctggtgaa aaagcattgt gagatctggg ccggagaata
    41221 agtcgggaat tgccttacag aagaatatcc ctgacaatgg tgttttaact tacatttaac
    41281 aatgttatga aacacccttt agaaaccttg accaccgcag caggcatttt gctgatggct
    41341 ttcctctctt gcctgctgct gcccgccccc gcactggggc tgacgctggc acaaaaactg
    41401 gtgaccacgt tccatctgat ggatcttagc cagctttaca cgttattgtt ttgtctgtgg
    41461 tttttagtgc tgggcgctat tgagtatttt gttctacgct ttatctggcg acgctggttc
    41521 tcgctggcgg attaaacgtc gattatcgcc gaacttcgcg gcatactttg cttattctcc
    41581 ttcgcctaaa ggaacattta tggataagca atcactgcac gaaacggcga aacgcctggc
    41641 tcttgagtta ccctttgtcg agctttgctg gccttttggc ccggagttcg atgtttttaa
    41701 aattggcggc aagattttta tgctgtcgtc ggagctgcgc ggcgtcccct ttattaatct
    41761 gaagtccgat ccacaaaaat ccctgctaaa tcagcaaata tacccaagca tcaagccagg
    41821 gtatcacatg aataaaaagc actggatttc ggtgtatccc ggcgaggaaa tctccgaagc
    41881 gttacttcgc gatctgatca acgattcgtg gaatctggtg gttgatggtc tggctaaacg
    41941 cgatcaaaaa cgactgcgtc ctgactcaac cgtaaatcaa tagcgcattt ttctcgctta
    42001 ccatttcatc tcgatccttg taatctgctg gcacgcaaaa ttactttcac atggagtctt
    42061 tatggatatc atttctgtcg ccttaaagcg tcattccact aaggcatttg atgccagcaa
    42121 aaaacttacc ccggaacagg ccgagcagat caaaactcta ctgcaataca gcccatccag
    42181 caccaactcc cagccgtggc attttattgt tgccagcacg gaagaaggta aagcgcgtgt
    42241 tgccaaatcc gctgccgata attacgtgtt caacgagcgt aaaatgcttg atgcctcgca
    42301 cgtcgtggtg ttctgtgcaa aaaccgcgat ggacgatgcc tggctgaagc tggttgttga
    42361 ccaggaagat gccgatggcc gctttgccac gccggaagcg aaagccgcga acgataaagg
    42421 tcgcaagttc ttcgccgata tgcaccgtaa agatctgcat gatgatgcag agtggatggc
    42481 aaaacaggtt tatctcaacg tcggtaactt tctgctgggc gtggcggcgc tgggtctgga
    42541 cgcggtgccc atcgaaggtt ttgacgccgc catcctcgat gaagaatttg gtctgaaaga
    42601 gaaaggctac accagtctgg tggttgttcc ggtgggtcat cacagcgttg aagattttaa
    42661 cgctacgctg ccgaaatctc gtctgccgca aaacattacc ttaaccgaag tgtaattctc
    42721 ccttgccggg catctgcccg gctatttccc ctcagattct cctgatttgc ataaccctgt
    42781 ttcagccgtc atcataggct gctgttgtat aaaggagacg ttatgcagga tttaatatcc
    42841 caggttgaag atttagcggg tattgagatt gatcacacca cctcgatggt gatgattttc
    42901 ggtattattt ttctgaccgc cgtcgtggtg catatttttt tgcactgggt ggtactgcgg
    42961 accttcgaaa aacgtgccat cgccagttca cggctttggt tgcaaatcat tacccagaat
    43021 aaactcttcc accgtttagc ttttaccctg caggggatta tcgtcaatat tcaggcggta
    43081 ttctggctac aaaaaggcac cgaagcggca gatattctga ctacctgcgc gcagttgtgg
    43141 atcatgatgt atgcgctgct ttcagtcttc tcgttgctgg atgtgatttt gaatctggcg
    43201 cagaaattcc cggcggcatc tcagttaccg ctgaaaggga tttttcaggg gattaaactg
    43261 atcggcgcga ttctggtcgg cattttgatg atctcgctgc tgattggtca gtcgccagcg
    43321 attctgatca gtggtcttgg tgcaatggct gccgtgctaa tgttggtatt taaagatccg
    43381 attcttggtc tggtggcagg tattcagctt tccgcgaacg atatgctgaa actgggtgac
    43441 tggctggaga tgccgaaata cggcgcggat ggcgcggtga tcgatattgg gttaaccacc
    43501 gtcaaagtgc gtaactggga caataccatt accactattc ccacctggtc tctggtttct
    43561 gactccttta aaaactggag cgggatgtca gcttctggcg ggcgacgtat taaacgcagt
    43621 atcagtattg atgtcaccag tattcgtttt cttgatgaag acgaaatgca acgcctgaat
    43681 aaagcgcatt tgttaaagcc ttatttaacc agccgccatc aggaaattaa tgagtggaat
    43741 cgccagcaag gttctacgga gtcggtatta aacctgcgcc gaatgaccaa tattggaacc
    43801 tttcgtgcct atctgaacga atatctgcgg aatcatccgc ggattcgcaa agatatgacc
    43861 ttaatggtac gccaactggc tcctggtgat aacggtttac cgcttgagat ctatgcgttt
    43921 accaacaccg tggtgtggct ggaatatgaa agcattcagg ctgatatatt cgatcacata
    43981 tttgcgattg tcgaagagtt tggtctgcga cttcatcagt cgccaaccgg caatgatatt
    44041 cgctctctgg cgggtgcatt taagcagtaa ttaaaaaaac cgctctcatc gaatggatga
    44101 gagcggcttt cagattgttg acatcatttt gtcggatgcg gcgtgaacgc cttatccgac
    44161 ctacagaatc gttacaaatt gtaggcccga taagcttgcg catcgggcaa atcagcctca
    44221 catcagctta attcactttc ctacgcaatg ttttaaacgc cacaaacagg aacacaatcc
    44281 acaccggcag cagaatcgct gacaagcgca tatcatccat cgtgcacatc agcagcaaaa
    44341 tcatgccgag gaaggcgatg caaagatagt tgccgaacgg atagagcagc gccttaaatt
    44401 gtgtttcacg cccctgacgt cgcatcgccg cgcgaaaacg cagatgcgcc aggcagatca
    44461 taatccagtt caacagcagc gttgctacca ccagcgccat cagcagacca aacgcttttt
    44521 gcggcagcag atagttgatt aacaccacca gcgaagtgat cgctccggaa agcatcagcg
    44581 agttaatcgg cacgccgcga cggctgacgc gagtcaaaaa ctttggcgca ttaccctgca
    44641 cagaaaggcc aaacagcatg cggctgttag agtaaacccc gctgttatac accgacagcg
    44701 atgccaccag aatgacgaag ttcagcgcag aagctaccac gttgctgtcg agattatgga
    44761 aaatcatcac aaacgggcta ctattggatt tcacttccac ccacgggtag agcgccagta
    44821 aaaccaccag tgaaccgata taaaacagca ggatgcgata caccacctga ttcactgctt
    44881 tagggatgct tttttccgga tcgcgcgctt cagccgcagt aatcccaatc agctccagac
    44941 cgccgaagga gaacataatt accgccagcg acaaaatcag tccattccag ccggtggcaa
    45001 agaaaccgcc gtagcgccag aggttatcga tactggcttt ctcaccgccg tgcccagaaa
    45061 acagcagcca caggccaaag ccgatcatac cgatgatcgc cagcacttta atcagcgcaa
    45121 accagaactc ggtttcgcca tataagcgca cgttcaccag gttaacggcg ttgatgataa
    45181 taaagaaggc ggcagcccaa atccacgttg gaacatccgg gaaccagtac tgcatataga
    45241 tgcccgcagc ggtcagctct gccattccca ccagcacgaa cattacccag tagttccagc
    45301 cagagaggaa gcccgcaaac ggtccccagt atttataggc aaagtgggca aatgaaccgg
    45361 ataccggctc ttcgaccacc atctcgccga gctggcgcat aatcaggaaa gcgatgatcc
    45421 cggcgacgcc gtagcccagc aatacagccg gacccgccat ctgaatcgcc gggccaatgc
    45481 caagaaacag accagtacca attgcgccac ccagcgcaat cagttgaata tgacggttat
    45541 gtaatccgcg atgaagcgtc ggctcttgat tcgacgcagt atcttccgat acggttgacg
    45601 cgtttttcac gcctttcccc tgtgtgtctt ttttgttgag gggcaccttt taacatttag
    45661 tgcccatcgt cgcaagacac aatccacacg gttaaacggg gtatcctgct tttatttccg
    45721 tacccgatgt cggtgcagcc acatcagctt atacgccgcc gggataataa acagcgacag
    45781 caaaggcgcg gtgatcatgc cgccaatcat cggcgcggca atccggctca tcacctctga
    45841 ccctgctcct gttccccaca gaatcggcag cagaccagcg ataatcaccg ccaccgtcat
    45901 cgcttttggg cgcacgcgca gtaccgcgcc gtgatataac gcctcatcca gcttctgctc
    45961 gctgaatgtt tgcggattat tcaacgacgg ctcggcctct atggcgtgac gtaaatacat
    46021 cagcatcacc acgccaaatt cggcggcgac cccggcaagg gcaataaaac cggtgcccgt
    46081 cgccacggaa agatgaaagc ccatccacca cagcaaccag atgccgccca ccagcgcaaa
    46141 cggtacgctg ctgataatca gcaacgcttc gcccacccga cggaacgcca gatacaacag
    46201 cacgaagatg atcatcagcg tcatcggcac catcagtttc agcttatggt tggcgcgctc
    46261 cagtagctcg aactgcccgg agaatgccac gctggtaccc ggttttaact gcactttttc
    46321 agctatcgct ttttgcagat cgtgaaccac cgacaccatg tcacgatcgc gggcatcgat
    46381 ataaatccag ctcgtcgggc gcgcattctc ggttttcagc atcgacggtc cggtagagac
    46441 tttaacgtcg gccacgtccg ccagagtgat ttgctgcttc atcggcgtga ggatcggcaa
    46501 ctggcgcagt gcctgcgggc tatcgcgcca gctttgcgga taacgcagat taattggata
    46561 acgagcaatc ccttccaccg tttcgccaac catcgccccg cccaccgcag aagtcacaaa
    46621 caactgcaca tccgccaccg tcataccgta acgcgcggct ttttcacggt taatctcaac
    46681 gttgatataa cgcccacctt ccagacgctc agcaagcgca gaagccacgc ctggcaccgt
    46741 tcgcgccact tcttcaattt gctccgccat cgtgtcgata tccgccagca cagtgccgga
    46801 aactttaatg ccgatagggc ttttaatgcc agtcgagagc atatcgatac ggttacgaat
    46861 tggcggcacc cacagattcg ccagccccgg cagacgcacg gtgttatcca gttcctcaat
    46921 gattttgtcc atcgtcatgc caggccgcca ctgatcctgc ggcttaagct ggatagtcgt
    46981 ttctaccatc tccagtggag ctgaatcggt ggcggtttcc gctttcccgg ttttgccaaa
    47041 tacccgcgcc acttccggta cgctcataat cagcttgtcg tttttttgca gcatgctcgc
    47101 cgcctctgct gcggaaatcc ccggcagcgt cgatggcata tacaacaagt cgccttcatt
    47161 gatctgcggt aaaaattccc cgccaacttt attgagcggc cagagaaccg tcagcaccga
    47221 aagcgctgcc accaacagcg tggttttcgg ccagtgcagt actttcagca acagcggatg
    47281 ataaacacga atcaaaaagc gattgagcgg gttactgctt tccggcggaa ttttgccacg
    47341 gatccagtag cccatcagga tcgggatcac tacgatcgcc agtagcgccg cgcccgccat
    47401 cgcataggtt ttggtgaacg ccagcgggcc aaacagacga ccttcctgcc cttccagggt
    47461 gaagatcggg ataaacgaca gcgtgataat cagcagactg ataaacagcg ccggccccac
    47521 ttcaacagat gcatcggtga tcacctgcca gcgcgtttta ttatccagcg tggcgtcagg
    47581 atgctggtgc tgccactctt ccagccgttt atgcgcattc tcgatcatga cgatagcggc
    47641 atcgaccatc gccccgacgg caatcgcaat gccacccaac gacataatat tggcgttcag
    47701 tccctgaaag tgcatgacaa taaaagcaat acacaacccc agcggcaacg aaataatcgc
    47761 caccagcgcc gagcgcacat gccagagaaa cagcgcacag actaccgcca ccacaataaa
    47821 ctcttccagc aacttgccgc tgaggttgtc aatggcgcgg tcaatgagct ggctgcgatc
    47881 gtatgttgta actatctcca cgccttccgg cagactgctt ttcagcgttt ccagtttgtc
    47941 cttcacagcg gcgatcactt cacgggcgtt tttgccggaa cgcaggatca ccaccccgcc
    48001 cgccacttcg ccttcgccgt tcagttcggc aatgccccgg cgcatctccg ggccaacctg
    48061 gaccttcgca acatcacgca gataaacggg cacgccattt tcactggctt ttaaaacgat
    48121 gtgattaaag tcgtcgagcg tttgcagata gccgctggcg cgcaccatat attccgcttc
    48181 cgccagttct atcgacgaac cgcccgcttc ctggtttgaa gcatccagcg cgctttttac
    48241 gtcggcgaga ctgatgccat actgcgccag gcgctgagga tcgctaacca cctgatactc
    48301 tttcaccaca ccgcccaccg acgccacttc cgcaacgtca gggatggttt ttagctcata
    48361 tttgagaaac cagtcctgca atgagcgtaa atcggccaga tcgtgcttac cgctgcgatc
    48421 caccagtgca tattcataga tccagccaac acccgtggca tctggcccca gctcggcgct
    48481 gactcccgca ggcagcttac cctgtacctg gttgaggtac tccagcaccc gcgagcgcgc
    48541 ccagtacgga tcggtgccat cttcgaaaat gacatacaca taagagtcgc caaactgcga
    48601 gaaaccgcgc acagtcttcg cgccaggcac cgacaacatg gtggtggtta gcggataagt
    48661 cacctgattt tcaacgattt gcggtgcctg accgggatag ctggttttaa taatcacctg
    48721 cacatcggaa agatccggca gtgcatccac tggcgtgtta atgatggtcc aggtgcccca
    48781 gatactcaga aacaacgcgc ccatcagcac cagaaaacgg ttcgccaccg agcgacgaat
    48841 aatccattca atcattggct attccctcaa tgcgcatggg tagcactttc agagcgcatc
    48901 cgctccagtg cgccagaaat attggcttca gaatcaatca ggaacaggcc gctggaaacc
    48961 accttttcac cttccgccag accagagcgt aacgcggtga cgccttgcga tgcctggaaa
    49021 acggcaacgc gtttcggtac aaagcgcccg tcagcatcaa cggtaatcac ccgctgttcg
    49081 ttgccggtat caatcagcgc ctgtgacgga atgagcagca tcggttcgct ggcggtattg
    49141 agttgcaacc cggcgttcat gcccggtttt agcgcctcgt cggcgttgtc gatttccaga
    49201 cgcaactgca gcgtgcgggt cgcggcatcc acgccgggta gcagggtcca tttgcgaatg
    49261 gtgagtgttt tatcaggtcg cgccggaacg gtgagcgtaa actgcgaggc atctttcacc
    49321 agccaggcga tggactccgg gatcgcagca gtgacccaca ccgggtccat accctgaatt
    49381 ttcgcgacca cgttatcttt ggcgatattc attcccgcgc gcagatcaaa cgcggtgatc
    49441 acgccatcaa tgggcgcttt gagcgtaaag cgagtctgga ttttttgcgt ggcgatcagg
    49501 cggcgaatat cagcctccgg cattcccgcc agtcgcagtc gctcaagaat gccttcagtc
    49561 tgggtcgccg taccgccggt ttcgcgcagc agtaaatact cactctgcgc ttccacccag
    49621 tcgggaatgg tcaggtcgag aagcggcgcg cccttttgca ctttatcgcc cacggtaagc
    49681 ggatacacct tgtcgataaa cccggcggcg cgggcctgca caatggcata ctgatactcg
    49741 ttgtaactga cattcgccgg gaaactctgg gaaaaagtca gcggcccgcg cgtgacggtc
    49801 gccgttttca cccccagatt ctgcgtctga gtcgggtcaa tgcgcacacc agacgcagaa
    49861 ctctcttcat cggcatattt cggcaccaga tccatatcca taaacggcga tttccctggt
    49921 ttatcgaacc gcgtattggg atacatcggg tcgtaccaga ataagacttt acgttctgcg
    49981 gtcgacgttt tttctgcggg cggttcctcc tttgcaaacc aggtaaaacc tgccgcagaa
    50041 ataataccgc ccgcgatcat gctgccgata ataagcgcga tttttttcat ctcattaaac
    50101 ccggattact ggctgacttt aatatcctgt aataaagaaa gattgccctg ctggacaaaa
    50161 ttaaacgcta ctttatcgcc ggttttaatt tcgctcattt tcgtctgcgg ggtgatggta
    50221 aagcgcatag tcatctccgg ccagttcacg gcagcaatcg gatcgtgatg gatggtgatt
    50281 tttttgcttt ccagatcaac accttttacc acgccagtgg cgctaataac ctgtggttgt
    50341 gcttcgctca tggtttcatg atgatgttcg ttagcctggg cattaaagcc aataacggta
    50401 aacagactga acattgcgac ttgcagtgct tttttcattt attctctcct ggagttaaaa
    50461 attattgctg ccaaccgccc cctaaggcgg tatataaaga aatttcgtta acctgacggg
    50521 cataattcag gtcaagtaaa gtttgtcggg ttgcaaataa agaacgttca gcatccagca
    50581 cttccagata actgactgcg ccgtgctgat ataatgcccg cgcccgttgc agggtaattt
    50641 gcagcgacgc aagataacgc tgctgggcgc tgatttgatc gttcaggctt tgacgtaatg
    50701 ccagcgcatc tgccacttct ttaaaggcgt tctggatttt ctgttcataa ttcaccaccg
    50761 actgctgctg gcgaatttcg gtgatatcca gattggcctg gttgcgtccg gcattaaaaa
    50821 tggggatctc aattttagga ataaaattcc acatcccgct gctggcgtta aataatgacg
    50881 acagatcgct gctggcggtt gatattccgc tggtcaggct gatagacggg aaaaatgccg
    50941 cacgcgcagc accaatattg gcattagccg ccattaacgc gtgttcagct tccataatat
    51001 cagggcgctg caataagatt tgcgacgaca agcccgccgg taatttaacg ctttgcaggc
    51061 tgtcgctgtt tactgtctgc gcttgcggca gcttgccgta gcttcccaat aacagttgca
    51121 atgcattatt cgcctgcgcc agttccccct gacgtttagc gatgtcgctg cgggtacttt
    51181 ctatcacccc gcgagcctgt tccagcgcca gaacattgct gctaccggtc aacagttgtt
    51241 tttcgacaaa cgcatatgac tgctgataat tacgcagcgt ttcttcggct atttgcaatt
    51301 gcgcatacgc cagttgctga ttgaaatagc tttgcgcgac attagaaacc aacagaatat
    51361 gcaccgcgcg ctgagcttcc tcagtggcta aataattttg gcgctcggct tcgctcatgt
    51421 tctttaagcg accgaaaaaa tcgagatcaa agctggcgtt aaggccagtc gataactccc
    51481 gcgtcgtggc tgaatcgcct ttaagattgc cgctccagct gccgctgccc tcgccattga
    51541 gctgtgggta gcggtcggca tcggtcagac gatattgcgc ccgcgcttcc tgcactttca
    51601 gcgccgccat gcgcaaatcc cggttattca ccaacgcctc gctaatcagc gtcttcacct
    51661 gattatcaac aaaaaaggtg cgccagcccg cgttctggta gttatctgct gcgttaacca
    51721 ggccgttctg gctgagtgag aactgctgcg gcacgggcat tgccggacgc tgataatccg
    51781 gtgccagtga acaaccggtt agcgcaaggg ccacacaaaa tggcagaagt ttacaaggag
    51841 acataggctc ataatttctg gtgattttat gctgccaact ttactcgcca ggctctgatt
    51901 ttccggtgac aggaaaatga caaaattgtc attttgccaa taagcgattg ccatctgatc
    51961 ccgctactct agaattgccc gggcaacatg cggaggaaat atgaaactgt tgattgtcga
    52021 agatgaaaag aaaaccggag aatacttgac caaagggtta accgaagccg gttttgtggt
    52081 cgatttggcc gacaacgggc tgaatggcta ccatctggcg atgaccggtg attatgatct
    52141 gataatcctc gatattatgc tgccggacgt gaacggctgg gatatcgtgc gcatgttgcg
    52201 ttccgccaat aaggggatgc cgattctgtt gcttaccgcg cttggcacca ttgaacatcg
    52261 cgtcaagggg ctggagttgg gggcggatga ctatctggtg aagccgttcg cttttgctga
    52321 actgctggcg cgggtgcgca ctctactgcg gcgcggagcg gcggtaatta tcgaaagtca
    52381 gtttcaggtt gccgatctga tggtcgatct cgtcagccgc aaagtcaccc gcagcggcac
    52441 gcgcatcact ctgaccagta aagaatttac tctgctggag tttttcctcc gccatcaggg
    52501 cgaagtgctg ccccgctcgc ttatcgcctc gcaggtatgg gacatgaatt ttgacagcga
    52561 taccaacgcc attgatgtgg cggtgaagcg gctgcgcggc aaaatcgaca acgactttga
    52621 gccaaagttg attcagaccg tgcgcggcgt gggttacatg ctagaggtgc cggatggtca
    52681 gtaagccatt tcagcgcccg ttttcgctgg caacccgcct gacctttttt atcagcctcg
    52741 ccaccatcgc ggcgtttttc gcctttgcat ggatcatgat ccactcggta aaagtgcatt
    52801 ttgccgagca ggatattaat gatttaaagg agattagcgc cacccttgaa cgggtactta
    52861 atcaccctga cgaaacgcaa gcccgacgct taatgacgct ggaagatatc gtcagtggtt
    52921 attccaatgt gttgatctcc ctggcaaata gccacggtaa aacggtgtat cactcccccg
    52981 gtgcgccgga tatccgcgag tttacgcgtg acgccatacc cgataaagac gcgcaggctg
    53041 gcgaggtgta tctcctttcc ggcccgacga tgatgatgcc agggcacggt cacgggcata
    53101 tggaacacag caactggcgg atgattaact tgccggttgg cccgctggtt gacggcaaac
    53161 cgatttatac gctctacatc gcgctttcga tcgattttca tcttcattac atcaatgatt
    53221 tgatgaataa acttattatg accgcatcgg taatcagcat cctgatcgtc tttatcgtgc
    53281 tgttggcggt acataaaggt cacgcgccga tccgcagcgt cagccgtcaa atccagaata
    53341 tcacctcgaa agatctcgac gttcgccttg acccgcagac cgtgcccatt gagctggaac
    53401 agctggtact gtcgttcaac catatgatcg agcgtattga ggatgtcttt acccgacagt
    53461 ccaatttctc agcggatatc gcccacgaaa ttcgcacacc tattactaat ctcattacgc
    53521 aaacggaaat cgccctcagc cagtcgcgca gccagaagga gctggaagat gtgctctact
    53581 ctaatctcga agaactgacg cgaatggcga aaatggtcag cgatatgctg tttctcgctc
    53641 aggccgataa caaccagcta atccccgaaa agaaaatgct caacctggcg gatgaagtcg
    53701 gcaaagtgtt cgattttttc gaggcgttag cagaagatcg cggcgtggag ctgcggtttg
    53761 ttggcgacga gtgtcaggtt gcgggcgatc cgctgatgct gcgtcgggcg ttaagcaacc
    53821 tgctttctaa tgccctgcgt tatacgccaa ccggagagac aattgttgtg cgctgccaga
    53881 cggtcgatca cctggtgcaa gttaccgtcg aaaaccccgg tacgcccatt gcgcccgaac
    53941 acttaccgcg attgtttgac cgtttctacc gcgttgatcc ttcccgccag cgaaaaggcg
    54001 aaggtagcgg cattggcctg gcgatagtga aatcgattgt tgtcgcgcat aaaggcacag
    54061 ttgcggtaac gtcagatgct cgggggacaa ggtttgttat catattaccc gcttaatcct
    54121 tcagcaaacg gcaactttta taaccagtgt aaaaataaca tgccgcaata gtaataccta
    54181 ttaatgataa aaagctgtca caattcataa aaaaccttaa tatacgccac cctaaacata
    54241 accagcgtta atgtaaggtt tttgtgtgga ctggcttctt gatgtttttg ctacctggct
    54301 ctacggctta aaagtaatcg cgataacgtt agcggtcatt atgttcatca gcgggctgga
    54361 cgattttttt attgatgtcg tctactgggt acgccgcatt aaacgcaagt tgagtgttta
    54421 tcgccgctac ccgcgaatga gttaccgcga actgtataaa ccagatgaaa aaccgttagc
    54481 gattatggtt ccggcgtgga atgaaacggg cgtcatcggc aatatggccg agctggcggc
    54541 gaccacgctc gactacgaaa actatcatat ctttgttggc acctacccca acgaccccga
    54601 tactcagcgt gatgttgacg aagtgtgcgc tcgcttcccg aacgtgcata aggtagtctg
    54661 cgcgcgtcct ggccccacca gcaaagccga ctgtctgaac aacgtgctgg acgccatcac
    54721 ccaatttgaa cgtagcgcca atttcgcttt tgctggtttt attctgcatg acgccgaaga
    54781 tgtgatttca ccaatggaat tgcgtctgtt caactatctg gtcgagcgta aagatctgat
    54841 tcagatccca gtgtatccgt tcgaacgcga atggacgcac ttcaccagca tgacctacat
    54901 tgatgagttt tcagaactgc atggcaaaga tgttccggtg cgtgaagccc tcgccggaca
    54961 ggtgcccagc gcaggagtcg gcacctgttt cagccgccgc gccgtgaccg cactgttagc
    55021 tgacggtgac ggtattgctt tcgacgtgca gagtctgact gaagattacg acattggctt
    55081 ccgcctgaaa gagaaaggta tgacggaaat ttttgtccgt tttccggtgg tggacgaagc
    55141 caaagaacgc gagcagcgta aatttttaca gcatgcgcgg acgtcaaaca tgatctgtgt
    55201 gcgcgaatat ttccccgata ccttttcgac tgcggttcgg caaaaatctc gctggatcat
    55261 cggcattgtt ttccagggct ttaaaaccca caaatggacc tccagcctga cgctgaacta
    55321 ctttctctgg cgcgaccgca aaggggcaat cagtaacttt gtcagcttcc tcgcgatgct
    55381 ggtgatgatc cagcttttgc tgttgctggc gtatgaaagt ttgtggcccg atgcctggca
    55441 tttcctttct attttcagcg gcagcgcatg gttaatgact ctgctgtggc taaactttgg
    55501 cttgatgatt aaccgcatcg tgcagcgggt gattttcgtt actggctact acggcctgac
    55561 gcaggggctg ctatctgtcc tgcgtctttt ctggggcaac ctgattaact tcatggccaa
    55621 ctggcgcgcg ttaaaacagg tacttcaaca cggcgatcca cgtcgtgtcg cgtgggataa
    55681 aacaacgcat gacttcccca gcgtgactgg cgatacccgc tcgttgcgtc cgttaggtca
    55741 aatcctgctg gaaaatcagg tcatcactga agaacaactc gatacagcac tgcgtaatcg
    55801 cgtcgaaggt ctacgcctgg gcggttcaat gctgatgcag gggctgatta gcgccgagca
    55861 actggcacag gcgctggcag agcaaaacgg cgtggcgtgg gaatccatcg atgcctggca
    55921 gatcccttcc tcgctgattg ccgaaatgcc ggcctccgtg gcgttgcatt atgcggtact
    55981 gccgctgcgt ctggacaatg atgagttaat tgtcggcagt gaagatggta ttgacccggt
    56041 ttcgctggcg gccctgacgc gtaaagtcgg acgcaaagtg cgttacgtca ttgttctgcg
    56101 aggacaaatt gtcaccggat tacgccactg gtatgcacgc cgacgcggtc acgatccgcg
    56161 ggcaatgttg tacaatgcag ttcagcatca gtggctcacg gaacagcagg ccggtgaaat
    56221 ctggcggcaa tatgtgccgc atcagttcct gttcgcagaa atactgacca cgctcggtca
    56281 tattaatcgt tcagcaatta acgtgttgtt attgcgccat gaacgcagtt ctctgccgct
    56341 cggcaagttt ttggtcaccg aaggcgttat tagccaggaa acgttggatc gcgtcctgac
    56401 aattcaacgc gaattacaag tttcgatgca atcactatta ctcaaagcag gtttaaacac
    56461 tgaacaggtt gcacaactgg agtccgaaaa tgaaggagaa taaccttaat cgcgtcatcg
    56521 gatggtctgg tttactgctg acatctttat tgagtaccag cgcactcgca gacaatatcg
    56581 gcaccagcgc agaagagctg gggctgagcg attatcgcca ttttgttatt tatccccgtc
    56641 tcgataaggc gctgaaggca cagaaaaata acgacgaagc aaccgccatc cgcgaatttg
    56701 aatatataca ccagcaggtg ccggataata ttccgctgac tttatacctt gcggaagcct
    56761 atcgccattt tggtcatgat gaccgggcgc ggctgttgct tgaggatcaa ctgaaacgtc
    56821 accctggaga tgaccggctt gagcgcagtc tggcggctat tccagttgaa gtgaaaagcg
    56881 ttacgactgt tgaagaactg cttgcccagc aaaaagcgtg cgatgctgcg ccgaccctgc
    56941 gttgtcgcag tgaagtcggg cagaatgccc tgcggctggc acaattacct gtcgccagag
    57001 cgcaacttaa cgatgcgacg tttgctgcat cgccggaagg aaaaacgttg cgaaccgatc
    57061 tgctgcaacg ggcaatctac ctgaaacaat ggtcccaggc agatacgcta tataatgaag
    57121 cacgccagca gaacacatta agcgcggcag aacgccgtca gtggtttgac gtgcttcttg
    57181 ccgcgcagct ggatgatcgg atcctggcgc tgcaatcaca ggggatcttc accgatcctc
    57241 agtcatatat tacttatgcg accgcgctgg cttatcgtgg cgaaaaagca cgcctccagc
    57301 attatctcat tgaaaataag ccgctgttta ccacggacgc acaagagaaa agttggctct
    57361 atctgttatc taaatacagc gccaaccccg ttcaggcgtt ggcgaattat acggtgcagt
    57421 ttgccgataa ccgccagtat gttgttggcg cgacgctacc agtgctgtta aaagaaggtc
    57481 agtacgacgc agcgcaaaaa ctgctcgcca ccctccccgc caatgaaatg cttgaggagc
    57541 gttatgccgt tagcgtagca acccgtaaca aggctgaagc tctgcgtctg gcacgattgc
    57601 tgtatcagca agaaccggca agtcttaccc gtctggatca actgacctgg caactgatgc
    57661 agaacgggca gtcacgcgaa gctgccgatt tattgctgca acgctatcct tttcagggcg
    57721 atgcgcgtgt cagccagacg ttaatggcgc gactggcgtc tctgctggaa agtcatcctt
    57781 acctggcaac gccggcgaag gtggcaattt tatcgaaacc tttaccgctg gcggagcaac
    57841 gtcagtggca aagtcagttg ccgggtattg ctgataattg cccggcaata gttcgcttgc
    57901 tgggcgatat gtcgccttct tacgatgctg ccgcctggaa ccgtctggca aagtgttatc
    57961 gggacacgct acccggtgtg gcgttgtatg catggcttca ggccgaacaa cgacaaccgg
    58021 acgcctggca acatcgtgcg gtagcctatc aggcgtatca ggttgaggac tatgccaccg
    58081 cactgacagc ctggcagaaa atcagtcttc acgacatgag caatgaggat ctgcttgctg
    58141 ccgccaatac cgcccaggcg gcaggaaatg gcgcggctcg cgatcgctgg ttacaacagg
    58201 cagaacaacg tggactggga aacaatgccc tctactggtg gctgcatgcg caacgttaca
    58261 ttccaggtca gccggaactc gcactgaacg atctcacgcg ctcaatcaat attgcgcctt
    58321 ctgccaacgc ttacgttgcg cgggcaacaa tttatcgcca acgtcataat atcccggcgg
    58381 cggtgagtga tttgcgcgcc gcgctggaac tggaaccgaa taatagcaac acccaggcag
    58441 cgcttggtta cgccttgtgg gatagcggtg atatcgcaca gtcgcgggaa atgctcgaac
    58501 aggcgcataa agggctaccg gacgatccgg cacttatccg acaactggcc tacgtgaacc
    58561 aacgtctgga tgacatgcct gcgacgcagc actacgcccg actggtgatt gatgacattg
    58621 ataatcaggc gctgataacc ccactgaccc cagagcaaaa tcagcaacgc ttcaatttcc
    58681 gccgtctgca tgaggaggtc ggtcgccgct ggtcgttcag tttcgattct tctatcggct
    58741 tgcgttccgg cgcaatgagt accgctaaca ataatgtcgg cggcgcagcg ccagggaaaa
    58801 gctatcgtag ctacgggcaa ctggaagccg agtaccgcct cggacgcaat atgctgctgg
    58861 aaggcgacct gctctcagtt tatagccgcg tctttgccga taccggtgaa aacggggtga
    58921 tgatgccggt gaaaaatccg atgtccggca ccggtctgcg ctggaagcca ctgcgcgatc
    58981 agatcttttt cctcgccgtc gaacagcagt tgccgctgaa cggacaaaat ggcgcatccg
    59041 ataccatgct gcgcgccagc gcctcattct ttaatggcgg caaatacagc gacgaatggc
    59101 acccgaacgg ttcaggctgg tttgcccaaa acctgtacct cgatgcggcg caatatatcc
    59161 gccaggatat tcaggcgtgg acggcagatt atcgcgtcag ctggcatcag aaggtggcga
    59221 acgggcagac tattgagcct tatgctcacg ttcaggacaa cggctatcgt gataaaggca
    59281 ctcagggcgc gcagcttggc ggtgtcgggg tccgctggaa tatctggacc ggcgagacgc
    59341 actacgacgc ctggccgcac aaagtcagtc tcggcgtcga atatcaacat acctttaagg
    59401 cgattaatca acgtaacgga gagcgcaaca acgcgtttct caccattgga gtgcactggt
    59461 aaatgcgtaa gttcattttc gtattgctga cactgctttt ggtcagccct ttttcctttg
    59521 cgatgaaagg tattatctgg caaccacaaa accgtgatag tcaggttacc gatacccagt
    59581 ggcaggggct gatgagtcag ttacgtttgc aaggcttcga tacactggtt ttgcaatgga
    59641 cccgttacgg cgatgcattc acccagccag aacagcgcgc gttattgttt aagcgtgcta
    59701 cagctgcgca acaggctggc ctgaagctga ttgtcgggct gaacgccgat ccggaatttt
    59761 ttatgcacca gaaacagtcg tccgcagcgc tggaaagcta tcttaatcgc ctgctggctg
    59821 ccgatctcca gcaagccaga ttatggagcg ccgtgcctgg cgtaacgccg gatggctggt
    59881 acatcagcgc ggaaattgac gacctgaact ggcgcagcga agccgcccgt cagcctttgc
    59941 taacatggtt aaacaacgcg cagcggttga ttagcgatgt ttcagcaaaa ccggtttata
    60001 tcagtatttt tttcgccgga aacatgtcgc cagatggcta tcgccaactg ctggaacaag
    60061 ttaaagcaac cggtgttaat gtctgggtac aggatggcag cggcgtggat aaactgaccg
    60121 ctgaacagcg tgaacgttat ctacaggcca gcgccgattg ccaaagttcc gccccagcaa
    60181 gcggcattgt ttatgaactg tttgtcgctg gtaaaggtaa aacgtttaca gcgaaaccga
    60241 aaccggatgc agagatcgcc tcgctgttag cgaaacgttc ctcttgcggt aaagacacgc
    60301 tctatttctc tctgcgctat ttgcccgtcg cgcagagtat ccttgagtat taatgattaa
    60361 agggagcaac ttagcttgct cctttccttt tcactttcct aatcaaaatc ctggcaagat
    60421 gaattattta gcagaatatc tgttttcatt ttattcgtct gacgtgttcc aattatttag
    60481 caaaaccgcg acaacaaagt gatggtgtaa tttgtaaaag ggaacaaata aatggctcgc
    60541 cctgcaggat tcgaacctgt agcccacggc ttagaaactc caggaacgac attttaagtc
    60601 aacaaattac cgcgccatct ctgcgttcac acgtcccact acctcaaaat atgtaaaacc
    60661 ttgcaagcca ttgcgaggcc ttatgtgtct cagttttgtt cctctttttt atactaaaaa
    60721 acacagcaat tgaggataaa cctcatgcta ttatcgctaa tatgcatcta aaggcatggc
    60781 acttgaatag ataaaaactc cacaaagaaa aaaataatta gcccataaaa ccacaatgca
    60841 aaacacaaac agacaattaa actaaaaaac tgacagtgca ttgtgacaaa aattcaatgt
    60901 taaacaaaat ataaacagtg gggcaatata caattgactc attaagttag atataaaaaa
    60961 tacatactca atcattaaaa cgattgaatg gagacctttt atgcgggcga aacttctggg
    61021 aatagtcctg acaaccccta ttgcgatcag ctcttttgct tctaccgaga ctttatcgtt
    61081 tactcctgac aacataaatg cggacattag tcttggaact ctgagcggaa aaacaaaaga
    61141 gcgtgtttat ctggccgaag aaggaggccg aaaagtcagt caacttgact ggaaattcaa
    61201 taacgctgca attattaaag gggcaattaa ttgggatttg atgccccaga tatctatcgg
    61261 ggctgctggc tggacaacac tcggcagccg aggtggcaat atggtcgatc aggactggat
    61321 ggattccagt aaccccggaa cctggacgga tgaaagtaga caccctgata cacaactcaa
    61381 ttatgccaac gaatttgatc tgaatatcaa aggctggctc ctcaacgaac ccaattaccg
    61441 cctgggactc atggccggat atcaggaaag ccgttatagc tttacagcca gaggtggttc
    61501 ctatatctac agttctgagg agggattcag agatgatatc ggctccttcc cgaatggaga
    61561 aagagcaatc ggctacaaac aacgttttaa aatgccctac attggcttga ctggaagtta
    61621 tcgttatgaa gattttgagc taggtggcac atttaaatac agcggctggg tggaagcatc
    61681 tgataacgat gagcactatg acccaggaaa aagaatcact tatcgcagta aagtcaaaga
    61741 ccaaaattac tattctgttg cagtcaatgc aggttattac gtaacaccta acgcaaaagt
    61801 ttatattgaa ggcgcatgga atcgggttac gaataaaaaa ggtaatactt cactttatga
    61861 tcacaatgat aacacttcag actacagcaa aaatggtgca ggcatagaaa actataactt
    61921 catcactact gctggtctta agtacacctt ttaacaacgt taaatagatt ttctccccgg
    61981 tggtattgta tagccccggg gaatttgttt accgttaaaa gcaaacaata tcccctaatc
    62041 ttgtaagcat ttaacctgcg tcctggcgtg taacctctta ccgcaacaca agactcaata
    62101 tattcaaatt cgttatgccg tggcatcatt taaccccttg taattcatcg ctataattga
    62161 tttaattcac aaataaaact ataacatggt gaaactaatg aaaaaaaaca cagatgatgg
    62221 ggctaaaatt tacacaccac ttaccctaaa gctttatgac tggtgggttt tgggtgtatc
    62281 aaatcggctt gcatggggat gtcctacaaa ggaacacctt cttccacact ttctggaaca
    62341 tttaggtaac aaccatctgg atattggcgt tggaactggg ttttacctta ctcacgtacc
    62401 tgagagtagt ctgatatctt taatggattt gaacgaagct agcctgaacg cggcatcgac
    62461 aagggctggg gaatcaaaaa ttaaacataa aattagccat gatgtttttg a
//
LOCUS       DAFGPF010000015        60294 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFGPF010000015 DAFGPF010000000
VERSION     DAFGPF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 60294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60294
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.015"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            137..703
                     /locus_tag="LSX49_001141"
     CDS             137..703
                     /locus_tag="LSX49_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7167577.1"
                     /translation="MNKKLLSLLVSGSLIAVVSTSVFATDTGVVNFNGKIVADTCEIN
                     VNESASTTGTVTFADTYPADYSGDGSIGTSKDFKIELIKCDPLVDKLNLTFSGTTTDA
                     GFLRLENSEAGAGSATNVGITVTNKNGGANDVKFDGSVPDASTDVDNAGSITPTIFNY
                     TANVIQVGNNAPTAGKYASSATFEVFYR"
     gene            749..1465
                     /locus_tag="LSX49_001142"
     CDS             749..1465
                     /locus_tag="LSX49_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBL7167578.1"
                     /translation="MSVFSRVCLGFTFLLTALQVQASIVLGGTRIIYPSNQNEVQITL
                     KNKDAYARYLVQSWVSNIDGSKAPFLITPPVYKLEENRQTLLHIVFTGDKNKLPQDRE
                     SLFLANIKSVSAMPEELKDRNTLQFAMKARLKLFWRPASLDNSDALTAWEKLKFHKEA
                     GKLIVKNPTPFYISFSDLTVSGKNIVPTESKSEPGALLMMVGPFSEQRFSLPVGAGSI
                     VEWSVITDYGSSSGKRQQKL"
     gene            1532..4009
                     /locus_tag="LSX49_001143"
     CDS             1532..4009
                     /locus_tag="LSX49_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBL7167579.1"
                     /translation="MLLPLHRTFVLTGITFALSAVYSLSYARDEFNLRILELDSPLEN
                     TQVLEDFVNNNNLTPGVYLTSVMWGQEYLDKRNITFILSSDKKRLIPRFTKADLREFG
                     LKVDDIPALQVMDDDTEFGDIAQIIDGARYDFQLDSQTLCLRIPQIYQNARAAGSISP
                     KYWSDGESAVWLSYYASGSRQNSDGDNLNSNWLNLNSGINLGVWRLRNNTVYSDSSWE
                     SISTSLQRDIKALRSQMEVGQTFTNGDLFDSVQMTGIKLETDTSMLPDSEQGFAPVVR
                     GIANSDAQVVIKQNGYVIYQTWVSAGPFEIKDLSQVTAGADLEVTIKETNGQEHSFIQ
                     ASSTVPILQREGALKYSLATGKYRDNDNHAETPVFGVATAIYGLPYGITIYGGILGAS
                     IYHSGVTGIGADLGRLGSVSVDITAAETKFDDGRDDATGLSWRAQYAKDFPDTDTTVT
                     LASYRYSTSQFYTFQEALDQRDTPDDKGIYSYRQTNNRRNRLQINLSQNIGRWGSVYL
                     NGYQQDYWGMHGAERSIGMGYSTTWSNINWSVNYTLTKTPGMAGEQQFSLTLNIPLSR
                     WLPDSWAMYNVNRSDKSNTSHQLGIGGTALQDNNLSYNLQQSYTDNNVGYDASMNGRY
                     RSSVGEFGLGYSYDKNSRQWNYSAQGAVVAHAHGVTLGQSVQDSFAIVHINEGANVKV
                     QNAQGVYTDYWGNAIVPNMTNYRHNAITVNTQGHDSLDISDATQDVIPSKGAVVGVDF
                     DARSGIRALLTLVHNKERVPFGALLTLGNSTAIVGEDGEVYITGVQESMTFTVQWGKE
                     INQQCTGVVTVPEKYTTGIYKATMDCR"
     gene            4031..5041
                     /locus_tag="LSX49_001144"
     CDS             4031..5041
                     /locus_tag="LSX49_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7167580.1"
                     /translation="MKPGFVSYIRTLLTIIFLSWGVIPEVFAGCNISGNGGNPATVQF
                     SVPALVVNSDAVPGTIIATVNANSPSISVSCTANGEIWQGYTVLTNGDMRTDNPLNNV
                     FQTNVPGIGFRAAWANNTSAQLTAGYLMTPWHKGSSTVIKGYGYPITIHAAIQFIVTG
                     PVGNGTIDTSKLVADWKYDNRVIGELRFSSVPVNIQPGTCDLIEKNITVPLNDIGTDD
                     FDVNNVSPVVSDDRFKIQIEKCSQDVKVDYRFTSSGSTGVTGNNILNIESGSGMAEGV
                     GLQILDSNNNVMVFDTDYTPVQKTTLNQNVTIPLKARYIKMGSVKSGRVNSVATFEVY
                     YR"
     gene            5261..7510
                     /gene="fhuA"
                     /locus_tag="LSX49_001145"
     CDS             5261..7510
                     /gene="fhuA"
                     /locus_tag="LSX49_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HBL7167581.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVAVGTRGASNTYDYLIIRGFAADGQSQNNYLNGLKMQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALD
                     DDGVYSYRLTGLARSANAQQKGAEEQRYAIAPAFTWRPNDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMIGYSFDHEFNDTFTVRQNLR
                     FAQNKVSQKSVYGYGMCSDPLYSSNPSSSPCANVPQSQWGHTLTRQYVIDNEKLENFS
                     VDTQLQSKFATGSVDHTLLTGVDFMRMRNDIDSWFGYAGSVAPSDIYNLDRSDFDFGA
                     HPNPSGPYRVLLKQKQTGLYVQDQAQWDKVLVTLGGRYDWADQSSFNRDYGNKSERDD
                     KEFTWRGGVNYLFDNGVTPYFSYSESFEPASQTDANGDLFAPSKGKQYEVGVKYVPED
                     RPIVVTGALYQLTKTNNLMADPNGSLFSVEGGEIRARGVELEAKAALSASVNLVGSYT
                     YTDAEYTTDTNYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPA
                     NSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQ
                     VVATATFRF"
     gene            7562..8359
                     /gene="fhuC"
                     /locus_tag="LSX49_001146"
     CDS             7562..8359
                     /gene="fhuC"
                     /locus_tag="LSX49_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HBL7167582.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILIDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGVADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            8359..9249
                     /gene="fhuD"
                     /locus_tag="LSX49_001147"
     CDS             8359..9249
                     /gene="fhuD"
                     /locus_tag="LSX49_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HBL7167583.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAVIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRILDNAIGGKA"
     gene            9246..11228
                     /gene="fhuB"
                     /locus_tag="LSX49_001148"
     CDS             9246..11228
                     /gene="fhuB"
                     /locus_tag="LSX49_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HBL7167584.1"
                     /translation="MSKRIALFPVLLLALLVVAAAALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLAISLLVGAGLGMVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVATERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPTGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     gene            complement(11263..12543)
                     /gene="hemL"
                     /locus_tag="LSX49_001149"
     CDS             complement(11263..12543)
                     /gene="hemL"
                     /locus_tag="LSX49_001149"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HBL7167585.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LREAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMSCDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            12768..14189
                     /gene="clcA"
                     /locus_tag="LSX49_001150"
     CDS             12768..14189
                     /gene="clcA"
                     /locus_tag="LSX49_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HBL7167586.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            14213..14278
                     /locus_tag="LSX49_001151"
     CDS             14213..14278
                     /locus_tag="LSX49_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167587.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            14271..14615
                     /gene="erpA"
                     /locus_tag="LSX49_001152"
     CDS             14271..14615
                     /gene="erpA"
                     /locus_tag="LSX49_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HBL7167588.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(14662..15285)
                     /locus_tag="LSX49_001153"
     CDS             complement(14662..15285)
                     /locus_tag="LSX49_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HBL7167589.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(15323..16123)
                     /gene="btuF"
                     /locus_tag="LSX49_001154"
     CDS             complement(15323..16123)
                     /gene="btuF"
                     /locus_tag="LSX49_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HBL7167590.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            complement(16116..16814)
                     /gene="mtnN"
                     /locus_tag="LSX49_001155"
     CDS             complement(16116..16814)
                     /gene="mtnN"
                     /locus_tag="LSX49_001155"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBL7167591.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            16898..18415
                     /gene="dgt"
                     /locus_tag="LSX49_001156"
     CDS             16898..18415
                     /gene="dgt"
                     /locus_tag="LSX49_001156"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HBL7167592.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLETYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            18545..19969
                     /gene="degP"
                     /locus_tag="LSX49_001157"
     CDS             18545..19969
                     /gene="degP"
                     /locus_tag="LSX49_001157"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HBL7167593.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGPGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSDLAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSST
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     gene            20124..21281
                     /gene="cdaR"
                     /locus_tag="LSX49_001158"
     CDS             20124..21281
                     /gene="cdaR"
                     /locus_tag="LSX49_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HBL7167594.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     gene            complement(21335..21721)
                     /locus_tag="LSX49_001159"
     CDS             complement(21335..21721)
                     /locus_tag="LSX49_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HBL7167595.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(22031..22855)
                     /gene="dapD"
                     /locus_tag="LSX49_001160"
     CDS             complement(22031..22855)
                     /gene="dapD"
                     /locus_tag="LSX49_001160"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HBL7167596.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFANYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(22886..25558)
                     /gene="glnD"
                     /locus_tag="LSX49_001161"
     CDS             complement(22886..25558)
                     /gene="glnD"
                     /locus_tag="LSX49_001161"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HBL7167597.1"
                     /translation="MNTLPEQYANTALPTLHGQPQNPCAWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     gene            complement(25620..26414)
                     /gene="map"
                     /locus_tag="LSX49_001162"
     CDS             complement(25620..26414)
                     /gene="map"
                     /locus_tag="LSX49_001162"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBL7167598.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     gene            26782..27507
                     /gene="rpsB"
                     /locus_tag="LSX49_001163"
     CDS             26782..27507
                     /gene="rpsB"
                     /locus_tag="LSX49_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBL7167599.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            27642..28493
                     /gene="tsf"
                     /locus_tag="LSX49_001164"
     CDS             27642..28493
                     /gene="tsf"
                     /locus_tag="LSX49_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBL7167600.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            28640..29365
                     /gene="pyrH"
                     /locus_tag="LSX49_001165"
     CDS             28640..29365
                     /gene="pyrH"
                     /locus_tag="LSX49_001165"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBL7167601.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            29515..30072
                     /gene="frr"
                     /locus_tag="LSX49_001166"
     CDS             29515..30072
                     /gene="frr"
                     /locus_tag="LSX49_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBL7167602.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            30164..31360
                     /gene="ispC"
                     /locus_tag="LSX49_001167"
     CDS             30164..31360
                     /gene="ispC"
                     /locus_tag="LSX49_001167"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBL7167603.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALKDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            31549..32307
                     /gene="ispU"
                     /locus_tag="LSX49_001168"
                     /gene_synonym="uppS"
     CDS             31549..32307
                     /gene="ispU"
                     /locus_tag="LSX49_001168"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HBL7167604.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            32320..33177
                     /gene="cdsA"
                     /locus_tag="LSX49_001169"
     CDS             32320..33177
                     /gene="cdsA"
                     /locus_tag="LSX49_001169"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBL7167605.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRIIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLVTAAVISWGYGMWVNLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            33189..34541
                     /gene="rseP"
                     /locus_tag="LSX49_001170"
     CDS             33189..34541
                     /gene="rseP"
                     /locus_tag="LSX49_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HBL7167606.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            34571..37003
                     /gene="bamA"
                     /locus_tag="LSX49_001171"
     CDS             34571..37003
                     /gene="bamA"
                     /locus_tag="LSX49_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HBL7167607.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            37125..37610
                     /gene="skp"
                     /locus_tag="LSX49_001172"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             37125..37610
                     /gene="skp"
                     /locus_tag="LSX49_001172"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HBL7167608.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            37614..38639
                     /gene="lpxD"
                     /locus_tag="LSX49_001173"
     CDS             37614..38639
                     /gene="lpxD"
                     /locus_tag="LSX49_001173"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HBL7167609.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            38744..39199
                     /gene="fabZ"
                     /locus_tag="LSX49_001174"
     CDS             38744..39199
                     /gene="fabZ"
                     /locus_tag="LSX49_001174"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL7167610.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            39203..39991
                     /gene="lpxA"
                     /locus_tag="LSX49_001175"
     CDS             39203..39991
                     /gene="lpxA"
                     /locus_tag="LSX49_001175"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HBL7167611.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            39991..41139
                     /gene="lpxB"
                     /locus_tag="LSX49_001176"
     CDS             39991..41139
                     /gene="lpxB"
                     /locus_tag="LSX49_001176"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HBL7167612.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGIATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNGARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            41136..41732
                     /gene="rnhB"
                     /locus_tag="LSX49_001177"
     CDS             41136..41732
                     /gene="rnhB"
                     /locus_tag="LSX49_001177"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBL7167613.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPSMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     gene            41769..45251
                     /gene="dnaE"
                     /locus_tag="LSX49_001178"
     CDS             41769..45251
                     /gene="dnaE"
                     /locus_tag="LSX49_001178"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBL7167614.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAESRGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLDTELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            45264..46223
                     /gene="accA"
                     /locus_tag="LSX49_001179"
     CDS             45264..46223
                     /gene="accA"
                     /locus_tag="LSX49_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBL7167615.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            46321..48462
                     /gene="ldcC"
                     /locus_tag="LSX49_001180"
     CDS             46321..48462
                     /gene="ldcC"
                     /locus_tag="LSX49_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HBL7167616.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RGEFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDSWF
                     FDIWQPPQVDEAECWHVAPGEQWHGFSDADANHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTEESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            48519..48908
                     /locus_tag="LSX49_001181"
     CDS             48519..48908
                     /locus_tag="LSX49_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL7167617.1"
                     /translation="MLGLKQVHHIAIIATDYAMSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            48973..50286
                     /gene="tilS"
                     /locus_tag="LSX49_001182"
     CDS             48973..50286
                     /gene="tilS"
                     /locus_tag="LSX49_001182"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBL7167618.1"
                     /translation="MTLTLNRQLLSSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTL
                     RAIHVHHGLSANADAWVKHCENICQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELEQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQTQQGTLKIAPMLAMSDARRAAIIRRWLAGQNAPMPSREALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVAGQSETIVPWQTWLQPLELPA
                     GLGSVQLTAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAVGENGVSFVWQKTLSQVKAG"
     gene            complement(50320..50580)
                     /gene="rof"
                     /locus_tag="LSX49_001183"
     CDS             complement(50320..50580)
                     /gene="rof"
                     /locus_tag="LSX49_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HBL7167619.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGATRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(50567..50767)
                     /locus_tag="LSX49_001184"
     CDS             complement(50567..50767)
                     /locus_tag="LSX49_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HBL7167620.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            50933..51478
                     /locus_tag="LSX49_001185"
     CDS             50933..51478
                     /locus_tag="LSX49_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HBL7167621.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFAYNSRAAQIWWQQNQSKCAQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTVWQQPS"
     gene            51475..51897
                     /gene="arfB"
                     /locus_tag="LSX49_001186"
     CDS             51475..51897
                     /gene="arfB"
                     /locus_tag="LSX49_001186"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL7167622.1"
                     /translation="MIVISRHVAIPDGEFEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAVIKDLTTEQ
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            51911..52621
                     /gene="nlpE"
                     /locus_tag="LSX49_001187"
                     /gene_synonym="cutF"
     CDS             51911..52621
                     /gene="nlpE"
                     /locus_tag="LSX49_001187"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308221.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HBL7167623.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAKSSMPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERGYLAARGNGEKPVLLSVEGHFTLEANPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGQ"
     gene            complement(52777..53601)
                     /locus_tag="LSX49_001188"
     CDS             complement(52777..53601)
                     /locus_tag="LSX49_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
                     /protein_id="HBL7167624.1"
                     /translation="MDKPKAYCRLLLPCFLLLSACTVDISQPDSSATAVNAEAKTWAV
                     KFQHQSSFTEQSIKEITEPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIYLGNNN
                     VAEATGAGVQIVSLKKAMKHSDKLFVLRVPDLTPQQATEITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSNVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRSGDVSAFKPETQLQYIGHLKPGIYIKASRFVGLTQ"
     gene            complement(53654..55372)
                     /gene="proS"
                     /locus_tag="LSX49_001189"
     CDS             complement(53654..55372)
                     /gene="proS"
                     /locus_tag="LSX49_001189"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBL7167625.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVLMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYL
                     VKQIKG"
     gene            complement(55483..56190)
                     /gene="tsaA"
                     /locus_tag="LSX49_001190"
     CDS             complement(55483..56190)
                     /gene="tsaA"
                     /locus_tag="LSX49_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HBL7167626.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVCFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(56187..56591)
                     /gene="rcsF"
                     /locus_tag="LSX49_001191"
     CDS             complement(56187..56591)
                     /gene="rcsF"
                     /locus_tag="LSX49_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HBL7167627.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(56709..57524)
                     /gene="metQ"
                     /locus_tag="LSX49_001192"
     CDS             complement(56709..57524)
                     /gene="metQ"
                     /locus_tag="LSX49_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HBL7167628.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(57564..58217)
                     /gene="metI"
                     /locus_tag="LSX49_001193"
     CDS             complement(57564..58217)
                     /gene="metI"
                     /locus_tag="LSX49_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HBL7167629.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTISAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(58210..59241)
                     /gene="metN"
                     /locus_tag="LSX49_001194"
     CDS             complement(58210..59241)
                     /gene="metN"
                     /locus_tag="LSX49_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HBL7167630.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            59429..60001
                     /gene="gmhB"
                     /locus_tag="LSX49_001195"
     CDS             59429..60001
                     /gene="gmhB"
                     /locus_tag="LSX49_001195"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HBL7167631.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMFLSARDYLHIDMAASYMVGDKLEDMQAAAAASVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPA"
BASE COUNT        14564 a        14535 c        16309 g        14886 t
ORIGIN      
        1 caggctatgt gttttttgtt ctaatctaaa aataatatta tttggtggat atatttctaa
       61 tatcaatatt tatcaagccc tgaccagtcg ctctggaatg gaatcatgtg tattacctca
      121 taattaaggg atttttatga ataaaaaatt gctttctctg ttagtgtcag gaagtctcat
      181 cgctgtagta agtaccagtg tatttgctac agataccgga gtggttaact ttaacggtaa
      241 aattgttgcc gatacttgcg aaattaatgt aaacgagtct gccagtacaa cagggacagt
      301 cacttttgca gatacttacc cagcggacta ttctggagac ggtagtattg gaacgtcaaa
      361 agattttaaa attgaattaa taaaatgcga tccgttggtg gacaaactaa acctgacatt
      421 ttctggaacg acaacggatg caggtttcct gcgtctggaa aatagcgaag ctggggctgg
      481 cagtgcaaca aatgtgggta ttacggtgac aaataaaaat ggcggtgcta acgatgtgaa
      541 atttgatggt tcagttcccg atgcatccac tgatgttgat aatgccggga gcattactcc
      601 aacaatattc aattacaccg ccaatgttat tcaggttggt aataacgcgc cgactgcggg
      661 taagtatgcc tcatctgcga cgttcgaagt attttatcgc taatattcat agtgtttgaa
      721 aggactgttt gaccacggag ggttatttat gtcagttttt tctcgagttt gtttaggttt
      781 tacgtttctt cttacggcat tgcaagttca ggcaagtatt gttcttggcg gtacacgtat
      841 tatctatcct tcaaatcaaa atgaagttca aatcacatta aaaaataaag atgcatatgc
      901 acgctatttg gtgcaaagct gggtgagtaa tattgatggc tctaaagccc cctttctcat
      961 tacgcctcca gtttataaac ttgaagaaaa tcggcaaaca ttactccata ttgtatttac
     1021 aggtgataaa aacaaacttc ctcaggatag ggaaagtttg tttctggcaa acataaaatc
     1081 tgtttctgcg atgccagaag aactaaaaga tagaaatacc ttgcaatttg caatgaaagc
     1141 ccggcttaaa ttattttggc ggccagcttc tttggataat agtgatgctc tcactgcatg
     1201 ggaaaaactt aagttccata aagaagcggg gaagctcata gtaaaaaatc caacgccttt
     1261 ttatatttca ttcagtgatc tgacagtatc gggaaaaaat attgttccca ccgagagcaa
     1321 atctgaacct ggcgcattat tgatgatggt aggaccattt tctgagcagc ggtttagtct
     1381 tcctgtcgga gcgggaagta ttgttgaatg gtcggtgata actgactacg gttcaagttc
     1441 tgggaaacga caacaaaagt tataaatcac cgaagtgtat tactataaat aaccgatctg
     1501 tatttataat attacgggcg caagggaatt tatgctgcta ccattgcatc gcacatttgt
     1561 cttaactggg ataacatttg cattatcggc agtgtattca ttgagctatg cacgagatga
     1621 atttaacctt cgtatcctgg agctggatag cccacttgaa aatacacaag tgctggagga
     1681 ttttgttaat aataataact taactccggg agtatatctt acctctgtta tgtgggggca
     1741 agagtatctt gataagagaa atattacctt cattctgtct tcggataaaa aaaggctcat
     1801 ccctcgtttt acaaaggcgg atctccgtga gttcggtctt aaagttgacg acattcccgc
     1861 gttacaagta atggatgatg acactgagtt tggtgatatt gctcagatta ttgatggcgc
     1921 acgttatgat ttccagttag acagccaaac gctgtgtctg cggatcccgc aaatctatca
     1981 gaatgcgcgg gccgcaggga gtatttcacc gaaatactgg agtgatggtg agagtgcggt
     2041 ttggttaagt tattacgcca gtggttcccg gcaaaacagt gatggcgata acctgaattc
     2101 aaattggttg aatttaaatt cagggattaa tttaggcgta tggcggctac gaaataatac
     2161 cgtttacagt gactccagtt gggagtcgat cagcaccagt ttgcaacgcg atatcaaagc
     2221 attaagaagc cagatggaag tcgggcagac gttcacaaat ggcgatcttt ttgacagtgt
     2281 gcagatgaca ggtataaagc ttgaaacgga caccagtatg ctgcctgaca gcgaacaagg
     2341 ctttgcgcca gtggttcgtg gtattgccaa cagcgatgca caagttgtga ttaaacaaaa
     2401 cggctatgtt atttaccaaa cgtgggtatc ggcagggcca tttgaaatta aagacttaag
     2461 ccaggtaacg gcgggggccg atctggaagt caccatcaaa gaaaccaacg ggcaagaaca
     2521 cagttttatt caggccagtt caacggttcc aattctacag cgagaaggcg cattaaaata
     2581 tagtcttgca actggaaaat accgtgacaa cgataatcat gctgagacac ctgtttttgg
     2641 tgttgcaacc gcgatatatg gcttgcccta tggaataacg atttatggcg gcatacttgg
     2701 tgcctcaatt tatcattctg gtgtgacagg gattggcgct gatttaggcc gtctggggtc
     2761 ggtatctgtt gatatcaccg cagcagaaac gaagtttgat gatgggcgtg atgatgctac
     2821 aggactgtca tggcgtgcac agtatgcgaa agattttcca gacactgata cgacagtaac
     2881 tctggcaagt tatcgttatt ctacatcaca attttacact ttccaggaag cacttgatca
     2941 acgtgataca cctgatgaca agggtattta cagttatcga cagacaaata atcggcgtaa
     3001 tcgtttacaa attaatcttt cacaaaatat tggtcgttgg ggctcggtct accttaacgg
     3061 ttatcaacag gattattggg gaatgcatgg ggccgaacgc agtataggaa tgggatacag
     3121 tacgacctgg agtaacatta attggtctgt taattacaca ctaacgaaaa cgccaggaat
     3181 ggctggtgag cagcaatttt cattaacact caatattcct ctctctcgct ggctgccaga
     3241 ttcatgggcg atgtataacg taaaccgttc cgataaaagt aatacatcac atcaattggg
     3301 aattggcggt actgctctgc aagataacaa cctgagttat aatttacagc aaagttatac
     3361 tgataataat gtgggttatg atgccagcat gaatggacgt tatcgtagct cagtggggga
     3421 attcggtctg ggatatagct atgataaaaa tagtcgtcag tggaattaca gtgcgcaagg
     3481 tgcggtggtt gctcatgctc atggagtaac attggggcaa tcagtgcagg attcattcgc
     3541 gatcgtgcat attaatgagg gtgccaatgt aaaagtacaa aatgcgcaag gcgtttatac
     3601 tgattattgg ggaaacgcga ttgttcccaa tatgacgaat tatcgacata acgctattac
     3661 tgtgaataca caggggcacg atagtcttga tatttctgat gccacacaag atgttattcc
     3721 ttcgaaaggg gctgttgttg gtgtcgattt tgatgcacgt agcggaatac gagccttgtt
     3781 gacattagtc cataataaag aacgcgtacc ctttggggca ttgctgacat tagggaatag
     3841 tacagcgatt gttggtgaag atggggaggt ttatattact ggtgtgcaag aatcaatgac
     3901 atttacggta cagtggggaa aagagattaa ccagcaatgt acaggagttg tcacagtgcc
     3961 agaaaaatac accacgggta tctataaagc cacaatggat tgccgataac aaataagaca
     4021 ggaaaaaata atgaagccag gattcgtctc ttatatacga acattattga ccataatatt
     4081 tcttagctgg ggcgtcattc ctgaggtttt cgccggttgt aacatttctg gaaatggagg
     4141 aaatccggca acagtacaat tctccgtgcc tgcgttggtt gttaatagcg atgccgttcc
     4201 tggaacgatt attgcgacag taaatgcgaa cagtccgtca atttcagttt cctgtacggc
     4261 aaatggtgag atctggcaag gatataccgt attgacaaac ggtgatatgc gtactgataa
     4321 cccacttaac aatgtgtttc agactaatgt gccaggaatc ggttttcgcg cggcgtgggc
     4381 gaataacacc agtgcgcaac tcaccgccgg atatttaatg acgccctggc ataaaggctc
     4441 gtcaacagtg attaaaggat atggttatcc gattacaata catgcagcta ttcagtttat
     4501 tgtcacagga cctgtcggta atgggaccat tgataccagc aaactggttg ctgactggaa
     4561 gtatgacaat cgtgttattg gagagcttcg ttttagttct gttccggtca atattcaacc
     4621 gggcacatgc gaccttatag aaaaaaatat taccgttcca ctcaatgata ttggcacaga
     4681 tgattttgat gttaacaatg tgtcacctgt agtttccgat gatcggttta aaattcagat
     4741 tgaaaaatgt tctcaggatg taaaagttga ttaccgcttt acttcatcag gttctactgg
     4801 agtaacgggt aataatattc ttaatattga gtctggttca ggaatggcgg aaggagttgg
     4861 tctgcagatc ctcgatagta ataacaatgt gatggtattt gatacagact atacacctgt
     4921 tcaaaaaacg acgttaaatc aaaatgttac tattccgtta aaagcacgct acatcaaaat
     4981 gggtagcgtc aaaagtggtc gggttaattc tgttgccacc ttcgaagtgt attaccgata
     5041 agcttttccc tttgccataa atgttaattt ttggtaatgg aatttttatg gtttacggtg
     5101 caaagattaa catttttgat tcatctgatt gattctcgcc ccttcatgga cgcacagagc
     5161 gtatatcact tgcgaacccg ccagcgtttc gaatattatc gcatctttat aataatcatt
     5221 ctcgtttacg ttatcattca ctttcatcag agatatacca atggcgcgtt ccaaaactgc
     5281 tcagccaaaa cactcactgc gtaaaatcgc agttgtagta gccacagcgg ttagcggcat
     5341 gtctgtttat gcacaggcag cggttgaacc gaaagaagac actatcaccg ttaccgctgc
     5401 acctgcgccg caagaaagcg catgggggcc agctgcaact attgcggcgc gacagtccgc
     5461 taccggcact aaaactgata cgccgattca aaaagtacct caatctattt ctgtcgtcac
     5521 cgctgaagag atggcactgc atcagcctaa gtcggtgaaa gaagcgctta gctatacccc
     5581 tggcgttgct gtgggaaccc gtggcgcatc taatacttat gattacctga tcatccgcgg
     5641 atttgcggca gacggccaaa gccagaacaa ctatctgaat ggcctgaaga tgcagggcaa
     5701 cttctataac gatgcggtta ttgacccata tatgctggag cgcgctgaaa tcatgcgtgg
     5761 cccggtttcc gtgctgtatg ggaaaagcag cccaggcggc ctgttgaaca tggtcagcaa
     5821 gcgcccgacc actgaaccgt tgaaagaagt tcagtttaag gccgggactg acagcctatt
     5881 ccagactggt tttgacttca gcgatgcgct ggatgatgac ggcgtttact cttatcgcct
     5941 gaccggcctt gcgcgttctg cgaatgccca gcagaagggg gctgaagagc agcgttatgc
     6001 tattgctcca gcgtttacct ggcgtccgaa tgataaaacc aatttcactt tcctttctta
     6061 cttccagaac gagccggaaa ccggttatta cggctggttg ccgaaagagg ggactgtcga
     6121 accgctgcca aacggtaagc gtctgccgac cgactttaac gaaggcgcga agaacaacac
     6181 ctattctcgt aacgagaaga tgattggtta tagcttcgac cacgaattta acgacacctt
     6241 tactgtgcgt cagaacctgc gctttgcaca aaataaagtc tcgcaaaaga gcgtatatgg
     6301 ctacggcatg tgctcagacc cgctctattc ttcaaacccc tcttcgagtc catgtgctaa
     6361 cgtgccgcag tctcaatggg gccatacact gactcgtcag tacgttatcg ataatgagaa
     6421 gttagaaaac ttctctgttg atactcagtt gcaaagcaaa ttcgcaaccg gttcagtgga
     6481 tcacactctg ctgactggcg ttgactttat gcgtatgcgt aatgacatcg attcctggtt
     6541 tggttatgcc ggttcagttg caccatctga tatctataat ttagaccgta gtgactttga
     6601 ttttggcgct cacccgaatc cgtctggtcc ataccgcgtt ctgctgaaac agaaacaaac
     6661 cggcctgtat gttcaggatc aggcgcagtg ggataaagtg ctggttacgc ttggcggtcg
     6721 ctatgactgg gccgatcagt catctttcaa ccgtgattac ggtaataaat ctgaacgtga
     6781 cgacaaagag ttcacctggc gtggtggtgt aaactacctg ttcgacaacg gcgtaacgcc
     6841 ttacttcagc tacagtgaat catttgaacc cgcttcacag actgatgcga acggcgatct
     6901 gtttgcacct tcgaaaggca aacagtatga agtcggcgtg aaatatgtgc cagaagatcg
     6961 cccaattgtg gtgactggcg cactgtatca gcttaccaaa actaataacc tgatggcgga
     7021 tccgaacggt tcactgttct cggttgaagg cggtgagatt cgtgcgcgtg gcgtagagct
     7081 ggaagcgaaa gcggcactgt cggcgagtgt taacttggtt ggttcttaca cctatactga
     7141 cgcggaatac accactgaca ccaactacaa aggaaatacg cctgcacagg tgccaaaaca
     7201 catggcttcg ctgtgggctg actatacctt ctttgacggt ccgctttcag gtctgacgct
     7261 gggcaccggt ggtcgttata ctggctccag ctatggtgat ccggctaact cctttaaagt
     7321 gggaagttat acggtcgtgg atgcgttagt gcgttatgat ctggcgcgag tcggcatggc
     7381 gggctccaac gtggcgctgc atgtcaacaa cctgttcgat cgtgaatacg tcgccagctg
     7441 ctttaacact tatggttgct tctggggcgc agaacgtcag gtcgttgcaa ccgcaacctt
     7501 ccgtttctaa tttctctttt tggggcacgg atttccgtgc ccgtttcaca agttggctgt
     7561 tatgcaggaa tacacgaatc attccgatac cacttttgca ctgcgtaata tctcctttcg
     7621 tgtgcccggg cgcacgcttt tgcatccgct gtcgttaacc tttcctgccg ggaaagtgac
     7681 cggtctgatt ggtcacaacg gttctggtaa atccactctg ctcaaaatgc ttggtcgtca
     7741 ccagccaccg tcggaagggg agattcttat tgatgcccaa ccgctggaaa gctggagcag
     7801 caaagcgttt gcccgcaaag tggcttattt gccgcagcag cttcctccgg cagaagggat
     7861 gaccgtgcgt gaactggtgg cgattggtcg ttacccgtgg catggcgcgc tggggcgctt
     7921 tggtgttgca gatcgcgaaa aggtcgagga agctatctcg ctggttggct taaaaccgct
     7981 ggcgcatcgg ctggtcgata gcctttctgg cggcgaacgt cagcgggcgt ggatcgccat
     8041 gctggtggcg caggatagcc gctgtctgtt gctcgacgaa ccgacttcgg cgctggatat
     8101 cgcccaccag gttgatgtac tggcgctggt gcatcgttta agtcaggagc gtggcctgac
     8161 ggtcattgcc gtgctgcacg atatcaatat ggcggcgcgc tactgtgatt atctggtcgc
     8221 cctacgcggc ggtgaaatga ttgctcaggg aacgcctgcg gaaattatgc gcggcgaaac
     8281 cctcgaaatg atttatggca tcccgatggg tattctgccg catccggcgg gtgctgcacc
     8341 tgtgagtttt gtttattgat gagcggctta cctcttattt cgcgccgccg actgttaacg
     8401 gcgatggcgc tttctccgtt gttatggcag atgaataccg cccacgcggc ggttattgat
     8461 cccaatcgta ttgtggcact ggagtggttg ccggtggagt tactgctggc gctcggcatc
     8521 gtgccttacg gcgtggcgga caccatcaac tatcgcctgt gggtcagcga accgccattg
     8581 ccggactcag tgattgacgt tggtttgcgt acagaaccca accttgaact gctgaccgaa
     8641 atgaaaccgt cgtttatggt ctggtctgca ggatatggcc cttcaccaga aatgctggca
     8701 cgtattgcgc cggggcgcgg atttaacttc agcgacggca aacagccact ggcgatggcg
     8761 cgtaaatcac tgacggaaat ggcagattta cttaacctgc aaagcgcagc ggaaacgcat
     8821 ttagcgcact atgaagactt tatccgcagc atgaaacccc gctttgtgaa gcgtggtgca
     8881 cgcccgttat tgctgacgac gcttatcgat ccgcgccata tgttggtctt cggtccaaac
     8941 agcttgttcc aggaaattct cgatgagtac ggcatcccaa atgcctggca aggggaaacc
     9001 aacttctggg gcagtaccgc cgtcagtatc gatcgtctgg cagcgtataa agacgttgat
     9061 gtgctctgtt ttgatcacga caacagcaaa gacatggatg cgctaatggc aaccccgctg
     9121 tggcaggcca tgccgtttgt ccgcgccgga cgctttcagc gcgtacctgc agtttggttc
     9181 tatggtgcga cgctttctgc aatgcacttt gtgcgtattc tggataacgc catcggaggt
     9241 aaagcgtgag taaacgaatt gcgctttttc cggtgttatt gctggcgctg ctggtggttg
     9301 ctgctgcggc gttgacctgg atgaacttct cgcaggcgct gccgcgcagc cagtgggcgc
     9361 aggccgcctg gtcgccggat attgacgtca tcgagcagat gatttttcac tacagcttgt
     9421 tgccgcgtct ggcgatttcg ctgctggtgg gcgcgggcct ggggatggtg ggcgtgctgt
     9481 ttcagcaagt gctgcgtaac ccgctggcgg aaccgacgac gttgggtgtt gcaacaggcg
     9541 cgcaactggg gattaccgtc accacgctct gggcgatccc cggcgcgatg gcgagccagt
     9601 ttgctgcgct ggcaggggct tgtgttgttg gcttaatcgt ctttggcgtc gcgtggggga
     9661 aacggctttc gccggtaacg ctgatcctcg cggggctggt agtgagcctt tattgcggcg
     9721 caatcaatca gttactggtt atcttccatc atgaccaact gcaaagcatg ttcctgtgga
     9781 gcaccggaac gctgacgcaa accgactggg gcggcgttga gcgtttatgg ccgcagctgc
     9841 tgggcggcgt gatgctgacg ttattgctac ttcgcccgtt aactctgatg gggcttgatg
     9901 atggcgtggc gcgcaatctc gggctggcct tgtcgctcgc tcgtctggcg gcgttgtcgc
     9961 tggcgattgt catcagtgcg ctgctggtga acgcggtggg gattatcggc tttatcggtt
    10021 tgttcgcgcc actgctggcg aaaatgctgg gggcgcggcg tttgttgcca cggttgatgc
    10081 tggcatcgct gattggtgcg ttaattctgt ggctttctga tcaaatcatc ctctggctga
    10141 ctcgcgtgtg gatggaagtg tctaccggtt cggtcactgc gttgatcggt gcgccgctgc
    10201 tactgtggct gctgccgcgt ttacgcagca ttagcgcgcc ggatatgaag gtcaacgatc
    10261 gtgtcgcgac tgaacgccaa cacgtgctgg cgtttgctct cgcgggcggc gtgctgctgt
    10321 tgatggctgt ggtggtggcg ctgtcgtttg gtcgtgatgc gcacggctgg acgtgggcga
    10381 gcggggcgtt gctcgaggat ttgatgccct ggcgctggcc gcgaattatg gcggcgctgt
    10441 ttgcgggtgt catgctggcg gtggcgggct gtattattca gcggctgacc ggaaacccga
    10501 tggcaagccc ggaagtgctg gggattagct ccggcgcggc gtttggcgtg gtgttaatgc
    10561 tgtttctggt gccgggtaat gcctttggct ggctgttacc cacaggcagt ctcggggcgg
    10621 cggtgacgct gttgatcatt atgatcgccg ccggacgcgg tggattttcc ccacaccgca
    10681 tgttactggc ggggatggcg ttaagtaccg cgttcaccat gcttttgatg atgttgcagg
    10741 caagtggtga cccgcgaatg gcgcaagttc tgacctggat ttccggttcg acctacaacg
    10801 cgaccgatgc gcaggtctgg cgtactggaa ttgtgatggt gattttgctg gcgattaccc
    10861 cgctgtgccg ccgctggctg accattttac cgctgggtgg tgataccgca cgagccgtgg
    10921 ggatggcgct gacgccgacg cgaattgcgc tgctgctgtt agcggcttgc ctgacggcga
    10981 ccgcgacaat gaccattggt ccgttgagtt ttgttggttt aatggcaccg catattgcgc
    11041 ggatgatggg ctttcgacgg acgatgccac acatcgtaat ttcggcgctg gtgggaggat
    11101 tactgctggt gttcgctgac tggtgtgggc ggatggtatt gtttccattc cagatcccag
    11161 cggggctgct gtcgaccttt atcggcgcgc catattttat ctatttgttg agaaagcaga
    11221 gccgttaata ggatgcctcg cccggtgggc gaggcaaaat catcacaact tcgcaaacac
    11281 ccgacgtgca gcatcgatgg tgttattgat atcttccatg ctgtgcgcca cagacataaa
    11341 gcccgcttca aacgctgacg gtgccagata aacaccttcg tccagcatca tatggaagaa
    11401 acgtttaaag cgttccacgt cacaggacat cacatcctgg tagcatgtca cggactcggc
    11461 gtcggtaaag aaaataccga acatgccgcc aacgtggttt accaccagcg gaattccggc
    11521 ttcttctgcc gcttcccgca gaccttctgc cagacgtgtt gtcagctcat ccagcgtctc
    11581 gtgaacgccc ggctgtgcga cttcattcag acaggcgaaa ccagcagcca tcgcaatcgg
    11641 gttaccggaa agcgtacccg cctgatagac cggaccggtc ggggccagcg catccattac
    11701 atcacgacga ccaccgaatg cgcctaccgg cattccaccg ccgatgattt tgccgaggca
    11761 ggtgagatcc ggttccacac cgtaataatc ctgtgcgcca gctagcgcta cgcggaaacc
    11821 ggtcatcact tcatcgatga tcagcaacgc gccaaattcg tcgcacagcg cgcgcagacc
    11881 tggcaggaac tctggcagcg gtggcacgca gttcatattg cctgccaccg gctcgacgat
    11941 aatacaggca atctcttgcg ggtattgctc aaacgcggcg cgtacagagg ccagatcgtt
    12001 ataagtacag gttaaggtat gtttggcgaa atctgccgga acacccggcg aatttggctg
    12061 gcctaacgtg agtgcgccag aaccggcttt caccagcaag cagtcagcgt gaccgtggta
    12121 acaaccttca aatttaataa ttttgtcgcg accggtaaaa ccacgggcca ggcggatggc
    12181 gctcatcgtc gcctcggtgc cggagttcac catgcgcacc atatccatgg tcgggaccag
    12241 ttcggtcacc agttgcgcca ttttcacttc catttcggtt ggtgcaccaa agcttaaacc
    12301 acgctcggcg gcttcaatca cggcattgcg gatcgccgga tggttatggc ccagcaccat
    12361 cggcccccag gaaccgacat aatcgatata ggctttgcca tcaacatcgt acagataagc
    12421 gccgtccgct ttttcgataa acagtggagt gccgcccacg ccagtaaagg cgcgaacagg
    12481 ggagttcacg ccgccaggga tcagctcgcg cgctgcgctg taaagatttt cagacttact
    12541 catggagggt tcctgattcg tagaaaaagt gaatggctgc tattctatgt tattcataac
    12601 aagttaaata ctcgtcaaac atcaggctgc ttgtactggt gcaatcctga tttcttagag
    12661 tataaaagtt ttgtgcattt gaaacattac gctttgcaaa ggattttcat ggaacgtgcg
    12721 agtaaaatgc cgtcatctta tttgtatgac caataagtga tcattggatg aaaactgata
    12781 ctccctcttt agaaacaccg caggccgcgc gcctgcgacg cagacaactg attcgccaac
    12841 ttcttgagcg cgataaaacc ccgttagcca ttttgtttat ggcggcagtc gtcggcacgc
    12901 ttgtcgggct ggctgcggtt gcttttgaca aaggtgtcgc ctggttgcag aaccaacgta
    12961 tgggggcact ggtacatact gctgataatt atccgcttct gttaaccgtc gcttttctct
    13021 gttcggcggt gctggcgatg ttcggctact ttttggtgcg caaatacgcg ccggaagcag
    13081 gtggttcggg gatcccggaa attgaagggg cgctggaaga tcaacgtcct gttcgctggt
    13141 ggcgtgtgtt gccggtgaaa ttctttggtg ggctggggac actcggcgga ggcatggtgt
    13201 tggggcgcga agggccaacc gtgcagatag gcggcaatat cgggcggatg gtactcgatg
    13261 ttttccgcct gaaaggtgac gaagctcgtc atacgctact ggcaaccggt gctgctgcgg
    13321 ggctggctgc ggcctttaac gcgccgctgg cgggtatttt gtttattatc gaagagatgc
    13381 gtccgcagtt tcgctatacg ttaatttcga ttaaagcggt atttattggc gtcattatgt
    13441 cgaccattat gtaccggatt tttaatcatg aagttgcgtt gattgacgtc ggtaaacttt
    13501 ctgatgcgcc gcttaatacg ctgtggcttt atctgatcct cggtattatt tttggcattt
    13561 tcggccctat ttttaataaa tgggtgctgg ggatgcagga tttgctgcac cgtgtgcacg
    13621 gtggcaatat taccaaatgg gtactgatgg gcggtgcgat tggcggtttg tgtggattgc
    13681 tggggtttgt ggcaccagca acttcgggcg gcggttttaa cctgattcct atcgctaccg
    13741 cggggaattt cagcatggga atgctggtgt ttatcttcgt cgcgcgggtc attaccacct
    13801 tactctgctt ctcttccggc gcgccgggcg gtatttttgc cccgatgctg gcgctgggta
    13861 ctgtgctggg aaccgctttc ggaatggttg ccgttgagtt gtttccgcaa tatcaccttg
    13921 aggcggggac gtttgctatt gccggaatgg gggcgttact ggcggcatct attcgcgcgc
    13981 cgttaacggg gatcattctg gttctggaaa tgaccgataa ctaccagctc attttgccaa
    14041 tgattattac cggtcttggc gcaacactat tagcacaatt taccggtggg aaaccgctat
    14101 actcggcgat tcttgcgcgc acgctggcaa aacaggaagc tgagcaactg gcgcgaagca
    14161 aggccgcatc agccagcgag aatacttgaa cgaaatacca gggtattaga taatggcgat
    14221 tattattggg ttagaatttg cccaattgcc gatgtcgttt ggagcaaaat atgagtgatg
    14281 acgtagcact gccgctggag tttaccgacg cagcagccaa caaagttaaa agcctgatcg
    14341 ctgacgaaga taacccgaat ctgaaattac gcgtgtatat caccggtggc ggttgcagcg
    14401 gcttccagta tggtttcacc tttgatgatc aggtgaacga aggcgatatg accatcgaaa
    14461 aacagggcgt tggcctggtg gttgatccga tgagcctgca atatctggtc ggcggttccg
    14521 ttgactatac cgaaggtctg gaaggttctc gtttcatcgt gaccaacccg aacgcgaaaa
    14581 gcacctgcgg ttgcggttct tcctttagta tctaatctgc tgttcatgtg ccggataaac
    14641 tatccggcac atctcctctc ttcaacgacc attctcatcc agcgcaaacg tcggtagctt
    14701 aagatgccaa cgaatagccg ccagccgaat caatagcgtc acgaccatgc ccatcatact
    14761 ggctgtttcc agtggtacgg aaaatgtgta ataagccgta gcgtggacaa taccgccgat
    14821 aatacaggca gttgcgtaga tttctgtacg taaaatcatg gggatttcgc gggccagtac
    14881 atcacgaatg attccgccgc caacgccagt aatgacgccc atacaaaccg cgattaacgg
    14941 accggcttcc gcattaaagg ctttattcac gccaatgccg acaaacaccg ccagaccaac
    15001 ggcgtccagc accggcaaca tccattttgg taagcgtctt ggctggcgca ccagcacgat
    15061 ggtcagcatg ctggtgacca ttgcaacgac cagatcggtg ggatctttca cccaaaatac
    15121 cgggccgtga tccagcgcca tgtcgcgaat tgttccgccg cctactgcgg taaccacgcc
    15181 caataccaga acaccaaaag ggtccatacg caattttccg gctaacaaaa cgccagagat
    15241 agcaaatacc gctgtgccga ctatatccag ccaatagacg agcattgttc aatccccact
    15301 gagcacctga aaaggtcagg cactaatcta cctgtgaaag cgcattacag agctgttgtg
    15361 cagcgaggat aatacgtggg cttgcacgtt caaaccagtc actcgtgaga ggaataacgg
    15421 gaattttgag ctgttcaccc cagtattgtt tgattttagg aatttggtcc ggtccgcctg
    15481 taatgacaat cgcctgtggc gagcgtgcta acacctgttc gcggctaact tgcggccagg
    15541 gaacccggct gtctttaaag atgttttctc cgccacaaac ttcgagtacc tggttctgaa
    15601 tcgactcttt tccactggta aatggcggat taatgccgaa ttgcagaaaa acacgttttt
    15661 taggtttatc agcatattgc gctttcaatt gcgcgtactg atccagcagg gattgcgcgg
    15721 cttgttcggc cttatccggt tgcggactcc agggggccag ttgacgtaac gcattggcaa
    15781 tttgttcaat gcttgtcgca tcgacccaca tcacttttat tcccagcgaa gccagctggt
    15841 caacctgccg ctcggcatta cctccacgcc aggcaatcac cagatcgggt ttcagcgcga
    15901 caatgcgttc cagattcatc ccctgccagg tggaaacctg ctcaatcttt tgcgcttgtg
    15961 gaggatagtc ggaatagctg ctgaccccaa ccggcgtgat cccggcggca aaggcaagtt
    16021 cagtgttggc gggagaaagc gtgatgacgc gcggcgcggc attgagccac agcggcgcga
    16081 gaaaagacag ggcgaccagc gccctgaaca gtgacttagc catgtgccag tttctgcacc
    16141 agtgactcaa ccatcaggct ggactgttta gcggcaacag ccaggaactc atcgaagcta
    16201 agatgagact gttgatcggc cacgtcggag atggcgcgta ctacgacaaa cgggacgttg
    16261 aaattgtggc agacatgggc gattgccgtc gcttccatct ctacagcaat ggcctgtggg
    16321 aagttgtggc ggattttcgc cagaccaaca gaaccgttga tgaaagcgtc gccgctaaca
    16381 atcaggccac gtacagcgtt aagattcagt tcggcaatgc aggcctcagc ggcagcgatc
    16441 agtttatcgt cagctttgaa gcctgccggg cagcctggta actgaccgta ttcataacca
    16501 aatgccgtga catccgcgtc gtgataacgc gcttcgtccg agacaacgat atcgcccact
    16561 ttcagcgttg gtgccaggcc accggcagaa ccggtgttaa taatcacatc tggcttgcag
    16621 tgttccaaca gcaaagtggc acccagcgcc gcagcgactt taccgatgcc cgatttcaga
    16681 agcgcaacct cggttccatt cagttggccg gtatagattt cgcaaccgcc cagactgata
    16741 gtttgacggt tttcgatttt gtcacgcagc agcgtaactt cttcttccat tgcaccaatg
    16801 atgccgattt tcatagattt actcgcgata agcccgattt gaaggcatag tttaccatgc
    16861 gcttacgggg aagcgtattt ctcacgcggg agaggacatg gcacagattg atttccgaaa
    16921 aaaaataaac tggcatcgtc gttaccgttc accgcagggc gttaaaaccg aacatgagat
    16981 tctgcggatc ttcgagagcg atcgcgggcg tatcatcaac tctccggcaa ttcgtcgtct
    17041 gcaacaaaag acccaggttt ttccactgga gcgcaatgcc gccgtgcgca cgcgtcttac
    17101 ccactcgatg gaagtccagc aggtggggcg ttatatcgct aaagagattt taagccgcct
    17161 gaaagagctt aaattactgg agacgtatgg tctcgatgaa ctgaccgggc cctttgaaag
    17221 cattgttgag atgtcatgcc tgatgcacga tatcggcaat ccgccgtttg gtcattttgg
    17281 cgaagcggcg ataaatgact ggtttcgcca gcgtttgtac ccggaagatg ccgaaagcca
    17341 gcctctgact gacgatcgct gcagcgtggc ggcactacgt ttacgggacg gggaagaacc
    17401 gcttaacgcg ctgcggcgca agattcgtca ggacttatgt cattttgaag gtaacgcaca
    17461 gggtattcgt ttggtgcata cattgatgcg gatgaatctc acctgggcgc aggttggcgg
    17521 tattttaaaa tatacccgtc cggcgtggtg gcgtggtgaa acgcctgaga cacatcacta
    17581 tttaatgaaa aagccgggct attatctttc cgaagaagcc tatattgccc ggttgcgtaa
    17641 agaacttaat ttggcgcttt acagtcgttt tccgttaacg tggattatgg aagctgccga
    17701 cgacatctcc tattgtgtgg cagaccttga agatgcggta gagaaaagga tatttaccgt
    17761 tgagcagctt tatcatcatt tgcacgaggc gtggggccag catgagaaag gttcgctctt
    17821 ttcgctggtg gttgaaaatg cctgggaaaa atcacgctca aatagtttaa gccgcagtac
    17881 ggaagatcag ttttttatgt atttacgggt aaacacccta aataaactgg taccctacgc
    17941 ggcacaacga tttattgata atctgcctgc gattttcgcc ggaacgttta atcatgcatt
    18001 attggaagat gccagcgaat gcagcgatct tcttaagcta tataaaaatg tcgctgtaaa
    18061 acatgtgttt agccatccag atgtcgagca gcttgaattg cagggctatc gggtcattag
    18121 cggattatta gagatttatc gtcctttatt aaacctgccg ttatcagact ttactgaact
    18181 ggtagaaaaa gaacgggtga aacgtttccc tattgaaacg cgcttattcc acaaactctc
    18241 gacgcgccat cggctggcct atgtcgaggc tgtcagtaaa ttaccgtcag attctcctga
    18301 gtttccgcta tgggaatatt attaccgttg ccgcctgctg caggattata tcagcggtat
    18361 gaccgacctc tatgcgtggg atgaataccg acgtctgatg gccgtagaac aataaccagg
    18421 cttttgtaaa gacgaacaat aaatttttac cttttgcaga aactttagtt cggaacttcg
    18481 cgctataaaa cgaatctgaa gaacacagca attttgcgtt atctgttaat cgagactgaa
    18541 atacatgaaa aaaaccacat tagcactgag tgcactggct ctgagtttag gtttggcgtt
    18601 atctccgctc tctgcaacgg cggctgagac ttcttcagca acgacagccc agcagatgcc
    18661 aagccttgca ccgatgctcg aaaaggtgat gccttcagtg gtcagcatta acgtagaagg
    18721 tagcacaacc gttaatacgc cgcgtatgcc gcgtaatttc cagcagttct tcggtgatga
    18781 ttctccgttc tgccaggagg gttctccgtt ccagagctct ccgttctgcc aggggggccc
    18841 gggcggtaat ggcggcggcc agcaacagaa attcatggcg ctgggttccg gcgtcatcat
    18901 tgatgccgat aaaggctatg tcgtcaccaa caaccacgtt gttgataacg cgacggtgat
    18961 taaagtccag cttagcgatg gtcgtaagtt cgacgcgaag atggttggca aagatccgcg
    19021 ctctgatatc gcgttgatcc agatccagaa cccgaaaaac ctgaccgcaa ttaagatggc
    19081 ggattctgat gcgctgcgcg tgggtgatta caccgtagca attggtaacc cgttcggcct
    19141 gggcgagaca gtaacttccg ggattgtctc tgcgctggga cgtagcggcc tgaacgctga
    19201 aaactacgaa aacttcatcc agaccgatgc agcgatcaac cggggtaact caggtggtgc
    19261 gttggttaac ctgaacggcg aactgattgg tatcaacacc gcgatcctcg caccggacgg
    19321 cggaaacatc ggtatcggtt ttgctatccc gagcaacatg gtgaaaaacc tgacctcgca
    19381 gatggtggaa tacggccagg tgaaacgtgg tgagttgggt attatgggca ctgagctgaa
    19441 ctccgatctg gcgaaagcga tgaaagttga cgctcagcgc ggtgctttcg taagccaggt
    19501 tctgccgaat tcttccgccg cgaaagcggg cattaaagcg ggtgatgtga tcacctcact
    19561 gaacggtaag ccaatcagca gctttgccgc actgcgtgct caggtgggca ctatgccggt
    19621 aggtagcaaa ctgaccctgg gcttactgcg cgacgggaag caggttaacg tgaacctgga
    19681 acttcagcag agcagccaga atcaggttga ttccagcacc atcttcaacg gcattgaagg
    19741 cgctgagatg agtaacaaag gcaaagatca gggcgtggtg gtgaacaacg tgaaaacggg
    19801 gactccggct gcgcagatcg gcctgaagaa aggtgatgtg attattggcg cgaaccagca
    19861 ggcagtgaaa aacatcgctg aactgcgtaa agttctcgac agcaaaccgt ctgtgctggc
    19921 actgaacatt cagcgcggcg acagcactat ctacctgtta atgcagtaat ctccctcaac
    19981 cccttcctga aaacgggaag gggttctcct tacaatctgt gaacttcacc acaactccat
    20041 acatcttcat catcctttgg gcatttgcac aatgccgtac gttacgtact tccttatgct
    20101 aagccgtgca taatggagga cttatggctg gttggcatct tgataccaaa atggcgcagg
    20161 atattgtggc acgtaccatg cgcatcatcg ataccaatat caacgtaatg gatgcccgcg
    20221 ggcgaattat cggcagcggc gatcgtgagc gtattggtga attgcacgaa ggagcattgc
    20281 tggtactttc acaaggacga gtcgtcgata tcgatgacgc ggtggcacgt catctgcacg
    20341 gtgtgcggca ggggattaat ctaccgttac ggctggaagg tgaaattgtc ggcgtaattg
    20401 gcctgacagg tgaaccagag aatctgcgta aatatggcga actggtctgc atgacggctg
    20461 aaatgatgct ggaacagtcg cggttgatgc acctgttggc gcaggatagc cgtttgcggg
    20521 aagaactggt gatgaacctg attcaggctg aggagaatac tcccgcactt actgaatggg
    20581 cgcaacggct ggggatcgat ctcaatcaac cgcgagtggt ggctattgtt gaggtcgaca
    20641 gcggtcagct tggtgtggac agcgcaatgg cggagttaca gcaactgcaa aatgcgctga
    20701 ctacgcccga gcgtaataat ctagtggcga ttgtctcgct aaccgaaatg gtggtgttga
    20761 aaccggcgtt gaactctttt gggcgctggg acgcagaaga tcatcgtaag cgagttgaac
    20821 aactgattac ccgcatgaaa gagtatggcc agctgcgttt tcgcgtttcg ctgggcaact
    20881 attttaccgg tcctggcagt attgcccgat cctatcgtac ggcgaaaacg acgatggtgg
    20941 tgggtaaaca gcggatgcca gaaagtcgct gctattttta tcaggatctg atgttacctg
    21001 tgttactcga cagtttgcgt ggcgactggc aggccaacga actggcgcga ccgctggcgc
    21061 ggctgaaagc gatggacaat aacggcttgc tgcggcgaac tctggcggcg tggtttcgcc
    21121 acaatgtgca accgctggca acgtcaaagg cgttgtttat tcatcgtaat actctggaat
    21181 atcggcttaa tcgtatatcg gaactgaccg ggcttgattt gggcaatttt gatgacaggt
    21241 tgctgctgta tgtggcgtta caactggatg aagagcggta ggtcgattac aaaattacag
    21301 ccgggtgaga ctttacccgg cccacagaat gacattattt acgcgtcagt ttttccagat
    21361 cggcttcaat ctcgctgatc ttattggtta ctactgactc caggtgacgt aagtcatcga
    21421 ggatcttacg cttaagatca acttcgctgc ggtcacgctg gcagatttga tcaagctcat
    21481 caatgatata ccgtagattc gggctgattt cctggacttc tttataaccc tgccccacac
    21541 catcagcgac aaccgtttta cgctgacgcg gatatttaaa cttcacgctc ttggcgaaaa
    21601 actcgccttt gtctttctgg aaatagattt tcagaatatc gttgttggct tcctgccgga
    21661 ggctgtaacg atcaatttct tcaggattgg taatacccag acttttcaga ttgtcgtaca
    21721 tagcgttacc tcaaaatgag tcagtaaatt gtgcttattt tagcatttgg cctggcccgc
    21781 ccggctcgac tgtgatcgca gaaagccttt ttcttccaga cttctatcat ggcgtaaaaa
    21841 tcaaaaaatt acctgcttta ttgtgatgat attccatggg atggattagc acatttatct
    21901 tcattttgcg aattacatga cagtccgaaa caagatgaaa acgtatttaa aaaaggggga
    21961 aaatgagtag gacgaattat tctgagccag aaagcaatcg ggcagcgtcg tgctgcccgt
    22021 gtacatactt ttagtcgatg gtacgcagca gttcgttaat accaacttta ccgcgagttt
    22081 tcgcgtcaac tttcttaacg ataactgcac agtagagact gtatttgcca tctttcgacg
    22141 gcagattacc tgaaacaacc acagaccctg ccggaacgcg accgtagtgg atttcgccgg
    22201 tttcacggtc ataaatacgg gtgctctgac caatgtatac gcccatagag atgacggaac
    22261 cttcttcgac aatcacccct tcaaccactt cagagcgtgc gccgatgaag cagttatctt
    22321 caataatggt cgggttagcc tgcagcggct ccagcacgcc gccgataccc acgccaccgg
    22381 aaaggtggac gtttttacca atctgcgcac aggaaccgac ggtcgcccag gtatcaacca
    22441 tggtgccttc atcaacatat gcgccgatgt tgacgtaaga cggcatcagc acggtgttac
    22501 gggcaatgaa cgcgccctga cgcactgccg ctggtggcac gacgcggaag ccttctttct
    22561 ggaaacgtgc ttcatcgtag ttagcgaatt tcatcggcac tttgtcgaag tagcggcttt
    22621 ctgccccttc gatcacctga ttatcattaa tacggaaaga gagcagcacc gcttttttca
    22681 accactgatg cgtcacccac tgaccgtcaa ttttttccgc tacacgcagt gcgccggaat
    22741 ccagcagggc gatcacctga tttaccgctt cgcgggtaac ggtgtctgca ttggctggcg
    22801 tgatctcggc acggcgttca aaagcggttt caataatgtt ctgtaactgc tgcattgtta
    22861 aactcttttc atatcagtaa acacatcacc ctttatcgtt tggattgagg gcctctgtca
    22921 accgctgatg cacttcctgc tgcaactcgt tattaagcgc acgccggtca gcggtggcaa
    22981 ttatgaataa atcttctact cgctcgccaa tggttgtaat tcgggcgcca tgaagcgaaa
    23041 ttcccagatc ggcaaaaatt ttcccgactc gcgccagcag tccaggttgg tcgagggcga
    23101 tcagttcgag gaacgatttg cggtcggtat gggtcggcaa aaacgtcact tcggtttcaa
    23161 cagtaaaatg gcgcaattta gcgggttggc gacggggctg cggtggctgc cagctacttt
    23221 gtgtcagcac ctgctccaga ccaaaccgaa taacctcatg acgatctgcg gatagcgggc
    23281 taccatcggg ttccagcact ataaaggtat ccatcgccat accgtcgcga gtggtgaaaa
    23341 tttgtgcgtc gtgaacactt aaattgcggc ggtctaattc ggcacagacg gcggcaaaca
    23401 gataggggcg gtccgggctc cagataaaaa tctcggtgcc tccacgcgta gcctgcgggc
    23461 taagcagtac cagcggtttg cttaaatcat gctgtaataa atggcgtgcg tgccaggcca
    23521 gttgatttgg gctatggcgg acaaaatagt tagcgcgaca gcgtgaccaa atttggtgca
    23581 gcgcctcttc gtcgatgtta tccatgcgca gtagtgccag cgcctggagt tggtgatggc
    23641 gaacccgttc gcgcatatcc ggcgtgtttt gcattccgcg tcgtagctgc ttttcggtgg
    23701 caaaatagag ttcgcgcaac agactttgct tccagctatt ccacagtgtt tcgttggtgg
    23761 cgcaaatgtc agccactgtc aggcatacca gatagcgcag acgattttcc gtttggactt
    23821 cttcggcaaa ctgcttgatg acttccgggt cctgaatatc gcggcgctga gctgtcaccg
    23881 acatcagcaa gtgctggcga accagccagg cgaccagctg tgtttcgcgt gagttcagcc
    23941 cgtggagttc ggcaaaatgc actacatcct gagcaccgag aatggagtgg tcgccgccgc
    24001 gtcctttggc gatatcgtga aacagcgcgg cgatgaaaat cagctcagtt gacggcagac
    24061 gcggccagac gtccacacac aacggatggc gctggcgcgt ttcttcactg gcaaaactct
    24121 ccagtttcaa catcacgcgg atagtatgtt catccaccgt gtaggcgtgg aacagatcaa
    24181 actgcatctg cccgacgata tgcgaccatt gcggcatata cgcgccgagt acgctatggc
    24241 gatgcattgg caatagcccg cgccgcaccg ctccggggtg acgcagaatg ctcaaaaaca
    24301 gttttcgcgc ttccggaata ttacacagag gttgttgcag atggcgacgg gcgtggcgta
    24361 actggcgtag cgtggtggag taaatgccgg tgatcgcact gttgcgcacc atggtgtaga
    24421 acatacgcaa gatggcttcc ggctggcgca taaatagtgt ttcatcacgc aggtcgatca
    24481 gcgttccgcg tagctgaaac tcatcgtcga ttggacgtgg tttttcgtcg gcgggaaggg
    24541 cgaggatggc ttcatcgaac agttgcagca gcatctggtt gagttcactg acgcggcgtg
    24601 taacgcggaa gtaatccttc atcatccgct cgaccggttc gttaccttca ccactgtaat
    24661 tcaaacgctg ggcgacgcta agctggcgat cgaataacag gcgattatcg taacgactga
    24721 cgaccagatg cagggcaaag cgaatgcgcc acaatatatg caggcattcg tttaattccg
    24781 ctcgctccgc agaggttaag aagccaaacc ctaccatttc atccagcgat gttgcgccaa
    24841 aatgacggcg ggccacccat tgcagagtgt ggatatcgcg caagccgccg gggctacttt
    24901 tgatgtctgg ttcaaggttg tagctggtgc cgtggtaacg ctgatggcgc tggttctgtt
    24961 cttcaacttt cgccgcgtag aacttgtcgg aaggccagaa tccttcgcta aaaatatgtt
    25021 tttgcagttc gaggaacagc gcaacatcgc caattaataa gcgggattcg attaaattgg
    25081 tggcgacggt taaatccgat aacccttcca gcatgcactc ttcaagcgtg cgcacgctat
    25141 gacccacttc cagctttaca tcccagagca gcgttaacag ctcgcccact ttttgcgcct
    25201 gatcgtccgg gagcttttta cggcttaaaa tcagtaaatc gatgtcagaa agtggatgca
    25261 gctcgccacg accgtagcca ccgacggcga ccaatgccag gtcggcaatc tggctgaatc
    25321 ccgcttcaat ccataatcgt tgaagaagct ggtcgataaa ctcggtacgc gcctcaatca
    25381 actgttctgc ggagatacca ttgtcaaagg catcacccag ccaacgctgg aaagtatcga
    25441 tatgggcttt tatcccaccg acggttaatt catcacgggg ccaggcgcat ggattttgcg
    25501 gttgaccgtg cagggtgggg agagcggtgt ttgcgtactg ttctggaagg gtattcattg
    25561 tgcgccaccc ataagattaa attattgcat taaaaaagcc ggcattcgcc ggcttcattt
    25621 tattcgtcgt gcgagattat cgccgggatg gtgtcatcct tgcgtagcgt cagaatttcg
    25681 cagccgttat cagtcaccac aatagtatgc tcatattgtg cagacaagct gcgatctttg
    25741 gtttttaccg tccagccatc tttcatggtg cggatctctt ttttacccgc gttgaccatt
    25801 ggctcgatgg tgaatgtcat ccccggtttc agcacgacgt tggtttcacg ggagtcatag
    25861 tgcagcacct gcggttcttc gtggaagccg cgaccaatac cgtgtccgca atattcacga
    25921 acgacggaga agccttctgc ttcgacaaat ttctgaattg ccgcaccgat ttcgcgcaga
    25981 ttaatgcctg gttttaccat gcgtagcgcc aggtacaggc tttcttgcgt gatgcggcac
    26041 agacgttcgc ccatgatggt cggcttaccg acgataaaca ttttcgaggt atcgccgtgg
    26101 aaaccatctt tgattacggt gacatcaatg ttaacgatat cgccatcttt cagcagcttg
    26161 gcgtcgtccg ggataccgtg gcacaccact tcattaatag agatgcaaac ggatttcgga
    26221 tagccgtgat agccgaggca ggcagaaacc gcgtgttgtt cattaacaat gtaatcatta
    26281 cagatgcgat ccagctcgcc ggtgctgacg cccggtttaa catacggttc gatcatctcc
    26341 agcacttcgg cagccagtcg gccagcgacg cgcatttttt cgatatcttc tggggtcttg
    26401 attgagatag ccattaattc tgtccatcag cgtcggtgat accgacaata tatatgtaag
    26461 tgccgtcaat ggtatcacac ccgggcaaat tgagaatcat tctgaatttc gccaaacgtg
    26521 ccactgaagg ttttctataa tagaaaattc aacgtctgat gctgtacaca gcgccaacaa
    26581 ttattggtgt ccacgacgta tttgtggtat aaagcgcgcc ggacttccga tccatttcgt
    26641 atacacagac tggacggaag cgacaatctc actttgtgta acaacacaca cgtatcggca
    26701 catattccgg ggtgcccttt ggggtcggta atatgggata cgtggaggca taaccccaac
    26761 ttttatatag aggttttaat catggcaact gtttccatgc gcgacatgct caaggctggt
    26821 gttcacttcg gtcaccagac ccgttactgg aacccgaaaa tgaagccgtt catcttcggt
    26881 gcgcgtaaca aagttcacat catcaacctt gagaaaactg taccgatgtt caacgaagct
    26941 ctggctgaac tgaacaagat tgcttctcgc aaaggtaaaa tccttttcgt tggtactaaa
    27001 cgcgctgcaa gcgaagcggt gaaagacgct gctctgagct gcgaccagtt cttcgtgaac
    27061 catcgctggc tgggcggtat gctgactaac tggaaaaccg ttcgtcagtc catcaaacgt
    27121 ctgaaagacc tggaaactca gtctcaggac ggtactttcg acaagctgac caagaaagaa
    27181 gcgctgatgc gcactcgtga gctggagaaa ctggaaaaca gcctgggcgg tatcaaagac
    27241 atgggcggtc tgccggacgc tctgtttgta atcgatgctg accacgaaca cattgctatc
    27301 aaagaagcaa acaacctggg tattccagta tttgctatcg ttgataccaa ctctgatccg
    27361 gacggtgttg acttcgttat cccgggtaac gacgacgcaa tccgtgctgt gaccctgtac
    27421 ctgggcgctg ttgctgcaac cgtacgtgaa ggccgttctc aggatctggc ttcccaggcg
    27481 gaagaaagct tcgtagaagc tgagtaataa ggcacgctcg tacgagccct tatagaccag
    27541 gtagtacacg tttggttagg gggcctgcat atggccccct ttttcacttt tatatctgtg
    27601 cggtttaatg ccgggcagat cacatctccg aggattttag aatggctgaa attaccgcat
    27661 ccctggtaaa agagctgcgt gagcgtactg gcgcaggcat gatggattgc aaaaaagcac
    27721 tgactgaagc taacggcgac atcgagctgg caatcgaaaa catgcgtaag tccggtgcta
    27781 ttaaagcagc gaaaaaagca ggcaacgttg ctgctgacgg cgtgatcaaa accaaaatcg
    27841 acggcaacta cggcatcatt ctggaagtta actgccagac tgacttcgtt gcaaaagacg
    27901 ctggtttcca ggcgttcgca gacaaagttc tggacgcagc tgttgctggc aaaatcactg
    27961 acgttgaagt tctgaaagca cagttcgaag aagaacgtgt tgcgctggta gcgaaaattg
    28021 gtgaaaacat caacattcgc cgcgttgctg cgctggaagg cgacgttctg ggttcttatc
    28081 agcacggtgc gcgtatcggt gttctggttg ctgctaaagg cgctgacgaa gagctggtta
    28141 aacacatcgc tatgcacgtt gctgcaagca agccagaatt catcaaacca gaagacgtat
    28201 ccgctgaagt ggtagaaaaa gaataccagg tacagctgga tatcgcgatg cagtctggta
    28261 agccgaaaga aattgcagag aaaatggttg aaggccgcat gaagaaattc accggcgaag
    28321 tttctctgac cggtcagccg ttcgttatgg aaccaagcaa aactgttggt cagctgctga
    28381 aagagcataa cgctgaagtg actggcttta tccgcttcga agtgggtgaa ggcatcgaga
    28441 aagttgagac tgactttgca gcagaagttg ctgcgatgtc caagcagtct taattatcga
    28501 aaaggagccg cctgagggcg gcttcttttt gtgcccatct tgtaaattca gctaaccctt
    28561 gtggggctgc gctgaaaagc gacgtacaat gtcgctagta ttaattcatt tcaatcgttg
    28621 acagtctcag gaaagaaaca tggctaccaa tgcaaaaccc gtctataaac gcattctgct
    28681 taagttgagt ggcgaagctc tgcagggcac tgaaggcttc ggtattgatg caagcatact
    28741 ggatcgcatg gctcaggaaa tcaaagaact ggttgaactg ggtattcagg ttggtgtggt
    28801 gattggtggg ggtaacctgt tccgtggcgc tggtctggcg aaagcgggta tgaaccgcgt
    28861 tgtgggcgac cacatgggga tgctggcgac cgtaatgaac ggcctggcaa tgcgtgatgc
    28921 actgcaccgc gcctatgtga acgctcgtct gatgtccgct attccattga atggcgtgtg
    28981 cgacagctac agctgggcag aagctatcag cctgttgcgc aacaaccgtg tggtgatcct
    29041 ctccgccggt acaggtaacc cgttctttac caccgactca gcagcttgcc tgcgtggtat
    29101 cgaaattgaa gccgatgtgg tgctgaaagc aaccaaagtt gacggcgtgt ttactgctga
    29161 tccggcgaaa gatccaaccg caaccatgta cgagcaactg acttacagcg aagtgctgga
    29221 aaaagagctg aaagtcatgg acctggcggc cttcacgctt gctcgtgacc ataaattacc
    29281 gattcgtgtt ttcaacatga acaaaccggg tgcgctgcgc cgtgtggtaa tgggtgaaaa
    29341 agaagggact ttaatcacgg aataattccc gtgatggata aataagggta agattccgcg
    29401 taagtatcgc gggggatctt acccgtaata tgtttaatca gggctatact tagcacactt
    29461 ccactgtgtg tgactgtctg gtctgactga gacaagtttt caaggattcg taacgtgatt
    29521 agcgatatca gaaaagatgc tgaagtacgc atggataaat gcgtagaagc gttcaaaacc
    29581 caaatcagca aaatacgcac gggtcgtgct tctcccagcc tgctggatgg cattgtcgtg
    29641 gaatattacg gcacgccgac gccgctgcgt cagctggcaa gcgtaacggt agaagattcc
    29701 cgtactctga aaatcaacgt gtttgatcgt tcaatgtctc cggccgttga aaaagcgatt
    29761 atggcgtccg atcttggcct gaacccgaac tctgcgggta gcgacatccg tgttccgctg
    29821 ccgccgctga cggaagaacg tcgtaaagat ctgaccaaaa tcgttcgtgg tgaagcagaa
    29881 caagcgcgtg ttgcagtacg taacgtgcgt cgtgacgcga acgacaaagt gaaagcactg
    29941 ttgaaagata aagagatcag cgaagacgac gatcgccgtt ctcaggacga tgtacagaaa
    30001 ctgactgatg ctgcaatcaa gaaaattgaa gcggcgctgg cagacaaaga agcagaactg
    30061 atgcagttct gatttcttga acgacaaaaa cgccgctcag tagatccttg cggatcggct
    30121 ggcggcgttt tgctttttat tctgtctcaa ctctggatgt ttcatgaagc aactcaccat
    30181 tctgggctcg accggctcga ttggttgcag cacgctggac gtggtgcgcc ataatcccga
    30241 acatttccgc gtagttgcgc tggtggccgg caaaaatgtc actcgcatgg tagaacagtg
    30301 cctggaattc tctccccgct atgccgtaat ggacgatgaa gcgagtgcga aacttcttaa
    30361 aacgatgcta cagcaacagg ggagccgcac cgaagtctta agtgggcaac aagccgcttg
    30421 cgatatggca gcgcttaagg atgttgatca ggtgatggca gccattgttg gcgctgctgg
    30481 actgttacct acgcttgctg cgatccgcgc gggtaaaacc attttgctgg ccaataaaga
    30541 atcactggtt acctgcggac gtctgtttat ggacgccgta aagcagagca aagcgcaatt
    30601 gttaccggtc gatagcgaac ataacgccat ttttcagagt ttaccgcaac ctatccagca
    30661 taatctggga tacgctgacc ttgagcaaaa tggcgtggtg tccattttac ttaccgggtc
    30721 tggtggccct ttccgtgaga cgccattgcg cgatttggca acaatgacgc ccgatcaagc
    30781 ctgccgtcat ccgaactggt cgatgggacg taaaatttcc gtcgattcgg ctaccatgat
    30841 gaacaaaggt ctggaataca ttgaagcgcg ttggctgttt aacgccagcg ccagccagat
    30901 ggaagtgctg attcacccgc agtcagtgat tcactcaatg gtgcgctacc aggacggcag
    30961 tgttctggcg cagctgggtg aaccggatat gcgtacgcca attgctcaca ccatggcatg
    31021 gccgaatcgc gtgaactctg gcgtgaagcc gcttgatttt tgcaaactaa gtgcgttgac
    31081 atttgccgca ccggattatg atcgttatcc atgtctgaaa ctggcgatgg aggcgtttga
    31141 acaaggccag gcagcgacga cagcattgaa tgccgcaaat gaaatcaccg tggctgcttt
    31201 tcttgcgcaa caaatccgct ttacggatat cgctgcgttg aatttatccg tactggaaaa
    31261 aatggatatg cgcgaaccac aatgtgtgga tgatgtgtta tctgttgatg cgaacgcgcg
    31321 tgaagtcgcc agaaaagagg tgatgcgtct cgcaagctga ggataatccg gctacagaga
    31381 gtcgcgctat ttgttagcgt agggcttcag tgatatagtc tgcgccatct gatcgtaagt
    31441 agttggcttt ataaggtcag gtatgccgtg gttttacacg gctttttttt gtataggctt
    31501 cagtattcct gagtaccgta aaccctgtca gggaataaga aacgcgtgat gttgtctgct
    31561 actcaaccac ttagcgaaaa attgccagcg catggctgtc gtcatgttgc gatcattatg
    31621 gacggcaatg gtcgctgggc aaaaaagcaa gggaagattc gtgcctttgg gcataaagcc
    31681 ggggcaaaat ccgtccgccg ggctgtctct tttgcggcca acaacggtat tgaggcgtta
    31741 acgctgtatg cctttagtag tgaaaactgg aaccgaccag cgcaggaagt cagtgcgtta
    31801 atggaactgt ttgtgtgggc gctagatagc gaagtaaaaa gtctgcaccg acataacgtg
    31861 cgtctgcgta ttattggcga taccagtcgc tttaactcgc gtttgcaaga acgtattcgt
    31921 aaatctgaag cgctaacagc cgggaatacc ggtctgacgc tgaatattgc ggcgaactac
    31981 ggtggacgtt gggatatagt ccagggagtc aggcaactgg ctgaaaaggt gcagcaagga
    32041 aacctgcaac cagatcagat agatgaagag atgctaaacc agcatgtctg tatgcatgaa
    32101 ctggcccctg tagatttagt aattaggact gggggggagc atcgcattag taactttttg
    32161 ctttggcaaa ttgcctatgc cgaactttac tttacagatg ttctctggcc cgatttcgat
    32221 gaacaagact ttgaaggggc gttaaatgcc tttgctaatc gagagcgtcg tttcggcggc
    32281 accgagcccg gtgatgaaac agcctgatgg gggtcgcttt tgctgaagta tcgcctgata
    32341 tctgcttttg tgttaatacc cgtcgtcatc gcggcgttgt ttctgttgcc gccggtgggg
    32401 ttcgccattg taacgctggt ggtctgtatg ctggcagcgt gggaatgggg acagcttagc
    32461 ggttttacca ctcgttcgca gcgagtatgg ttggcggtgt tatgcgggtt attgttggcg
    32521 ctgatgcttt ttctgttgcc ggaatatcac cgaaatattc atcaaccgct ggttgaaatc
    32581 tcactttggg cttcgctggg ttggtggatt gtcgcgctat tgctggtgct gttttaccca
    32641 ggttccgcag caatctggcg taactctaaa acattgcgca ttatttttgg cgtgctaacc
    32701 attgttccct tcttctgggg catgctggcg ttacgggcct ggcactacga cgagaatcat
    32761 tacagtggcg caatatggct gctctatgtc atgatcctgg tatggggcgc tgactctggc
    32821 gcatatatgt ttggcaaatt gtttggtaaa cataaactgg caccgaaggt ttctccgggt
    32881 aaaacctggc aaggctttat cggtggactc gtgaccgcag cggtaatctc atggggttat
    32941 ggcatgtggg tgaatctcga cgtcgctccc gtcaccttac tcatttgctc tattgtcgca
    33001 gcgttagcct cagtgctcgg cgatctgacc gaaagtatgt ttaagcgtga agcgggaatt
    33061 aaggacagcg gtcatttaat tccaggacac ggtggtattt tagatcgtat tgatagcctg
    33121 acggctgcgg taccggtctt tgcttgcttg ttgttactgg tattcaggac gctttaacgg
    33181 aaggtaatat gctgagtttt ctctgggatt tggcttcgtt catcgttgca ctgggtgtac
    33241 ttatcaccgt gcatgaattt ggtcatttct gggttgcccg gcgttgtggt gttcgcgttg
    33301 agcgtttctc aatagggttt ggtaaggcgc tctggcggcg aactgataag ctcggcaccg
    33361 aatatgttat cgccctgatc ccgttgggcg gttatgtcaa aatgctggat gagcgcgcag
    33421 aaccggtcgt tccggaactc cgccaccatg ccttcaataa taaatctgtc ggccaacgag
    33481 cggcgattat tgccgcaggt ccagttgcaa acttcatttt tgctatcttt gcctactggc
    33541 tggtttttat tattggtgtg cctggcgtac gtccggtggt tggtgaaata gcagccaatt
    33601 cgatagctgc ggaagcacaa attgcaccag gtacggaact aaaagccgta gatggtatcg
    33661 aaacgcctga ttgggatgcc gtgcgtttgc agttggtcga taaaattggc gatgaaagca
    33721 ccaccattac ggtagcgcca tttggcagcg accaacggcg ggatgtaaag ctcgatttac
    33781 gtcactgggc gtttgagcct gataaagaag atccggtatc ttcgttgggg attcgtcctc
    33841 gtgggccgca aattgaacct gtactggaaa atgtgcagcc aaactcggcg gcaagcaagg
    33901 caggtttgca agcaggcgac aggatcgtta aagtcgatgg tcagccctta acgcagtggg
    33961 tgacctttgt gatgcttgtc cgggataacc cgggtaaatc cttagcgtta gaaatcgaaa
    34021 gacaggggag tcccttgtct ttgacattaa tcccggagag taaaccgggt aatggtaaag
    34081 cgattggttt tgtcggtatt gagccgaaag tcattccttt gcctgatgag tataaagttg
    34141 tacgccagta tgggccgttc aacgctatcg tcgaagccac ggacaaaacg tggcagttga
    34201 tgaagctgac ggtcagtatg ctgggaaaat tgatcaccgg tgatgtgaaa ctgaacaacc
    34261 tcagtgggcc gatctctatc gccaaggggg ctgggatgac agcggaactc ggggtagttt
    34321 attacctgcc gtttcttgcg cttattagcg tgaacttagg gataattaac ctgtttccgt
    34381 tgcccgtact tgacgggggg catctgctgt tccttgcgat cgaaaagatc aagggcggac
    34441 cggtatccga gcgggttcaa gacttttgtt atcgcattgg ctcgattctg ctggtgctgt
    34501 taatggggct tgcacttttc aatgatttct ctcggttatg agagttagtt aggaagaacg
    34561 cataataacg atggcgatga aaaagttgct catagcgtcg ctgctgttta gcagcgccac
    34621 cgtatacggt gctgaagggt tcgtagtgaa agatattcat ttcgaaggcc ttcagcgtgt
    34681 cgccgttggt gcggccctcc tcagtatgcc ggtgcgcaca ggcgacacgg ttaatgatga
    34741 agatatcagt aataccattc gcgctctgtt tgctaccggc aactttgagg atgttcgcgt
    34801 ccttcgtgat ggtgataccc ttctggttca ggtaaaagaa cgtccgacca ttgccagcat
    34861 tactttctcc ggtaacaaat cggtgaaaga tgacatgctg aagcaaaacc tcgaggcttc
    34921 tggtgtgcgt gtgggcgaat ccctcgatcg caccaccatt gccgatatcg agaaaggtct
    34981 ggaagacttc tactacagcg tcggtaaata tagcgccagc gttaaagctg tcgtgacccc
    35041 gctgccgcgc aaccgtgttg acctaaaact ggtgttccag gaaggtgtgt cagctgaaat
    35101 ccagcaaatt aacattgttg gtaaccatgc tttcaccacc gatgaactga tctctcattt
    35161 ccaactgcgt gacgaagtgc cgtggtggaa cgtggtaggc gatcgtaaat accagaaaca
    35221 gaaactggcg ggcgaccttg aaaccctgcg cagttactat ctggatcgcg gttatgcccg
    35281 tttcaacatc gattctaccc aggtcagtct gacgccagat aaaaaaggta tttacgtcac
    35341 ggtgaacatc accgaaggcg atcagtacaa gctttctggc gttgaagtga gcggcaatct
    35401 tgccgggcac tccgctgaaa ttgagcaact gactaagatc gagccgggcg agctgtataa
    35461 cggcaccaaa gtgaccaaaa tggaagatga cattaaaaag cttcttggtc gctatggtta
    35521 tgcctatccg cgcgtacagt cgatgcctga aattaacgat gccgacaaaa ccgttaaatt
    35581 acgcgtgaac gttgatgcgg gtaaccgttt ctatgtgcgt aagatccgtt ttgaaggtaa
    35641 cgatacctcg aaagatgctg tcctgcgtcg cgaaatgcgt cagatggaag gtgcatggct
    35701 ggggagcgat ctggtcgatc agggtaagga gcgtctgaac cgtctgggct tctttgaaac
    35761 tgtcgatacc gatacccaac gtgttccggg gagcccggat caggttgatg tagtttacaa
    35821 ggtgaaagaa cgtaacaccg gtagcttcaa cttcgggatt ggttacggta ctgaaagtgg
    35881 cgtgagcttc caggctggtg tgcaacagga taactggtta ggtacgggtt atgctgttgg
    35941 tatcaacggg accaaaaacg attaccagac ctatgctgaa ctgtcggtaa ccaacccgta
    36001 cttcaccgta gatggcgtaa gcctcggtgg tcgtctcttc tataatgact tccaggcaga
    36061 tgacgccgac ctgtccgact ataccaacaa gagttatggt acagacgtga cgttgggctt
    36121 cccgatcaac gaatataact cgctgcgtgc aggtctgggt tatgtacata actccctgtc
    36181 caacatgcag cctcaggttg cgatgtggcg ttatctgtac tctatgggtg aacatccgag
    36241 cacctctgat caggataaca gcttcaaaac ggacgacttc acgttcaact atggttggac
    36301 ctataacaag cttgaccgtg gttacttccc gacagatggt tcacgtgtca acctgaccgg
    36361 taaagtgacc attccgggat cggataacga atactacaaa gtgacgttag acacggcgac
    36421 ttatgtgccg attgatgacg atcacaaatg ggttgttctg ggtcgtaccc gttggggtta
    36481 tggtgatggt ttaggcggca aagagatgcc gttctatgag aacttctatg ccggtggttc
    36541 cagcaccgtg cgtggcttcc agtccaatac cattggtccg aaagcagttt acttcccgca
    36601 tcaggccagt aattatgatc cggactatga ttacgaatgt gcgactcagg acggcgcgaa
    36661 agatctgtgt aaatcggatg atgctgtagg cggtaacgcc atggcggttg ccagcctcga
    36721 gttcatcacc ccgacgccgt ttattagcga taagtatgct aactcggttc gtacttcctt
    36781 cttctgggat atgggtaccg tttgggatac aaactgggat tccagccaat attctggata
    36841 tccggactat agtgatccaa gcaatatccg tatgtctgcg ggtatcgcat tacaatggat
    36901 gtccccattg gggccgttgg tgttctccta cgcccagccg ttcaaaaagt acgatggaga
    36961 caaggcagaa cagttccagt ttaacatcgg taaaacctgg taagtgttct ccacaaagga
    37021 atgtagtggt agtgtagcga tgactttagg cgatcaatat aagatcgccg ggccacgcaa
    37081 agaactgcac cctccggtgc aaatgggatg gtaaggagtt tattgtgaaa aagtggttat
    37141 tagctgcagg tctcggttta gcactggcaa cttctgctca ggcggctgac aaaattgcaa
    37201 tcgtcaatat gggcagcctg ttccagcagg tagcgcagaa aaccggtgtt tctaacacgc
    37261 tggaaaacga gttcaaaggc cgtgccagcg aactgcagcg tatggaaacc gatctgcagg
    37321 ctaaaatgaa aaagctgcag tccatgaaag cgggcagcga tcgcactaag ctggaaaaag
    37381 acgtgatggc tcagcgccag acttttgctc agaaagcgca ggcttttgag caggatcgcg
    37441 cacgtcgttc caacgaagaa cgcggcaaac tggttactcg tatccagact gctgtgaaat
    37501 ccgttgccaa cagccaggat atcgatctgg ttgttgatgc aaacgccgtt gcttacaaca
    37561 gcagcgatgt aaaagacatc actgccgacg tactgaaaca ggttaaataa gtaatgcctt
    37621 caattcgact ggctgattta gcgcagcagt tggatgcaga actacacggt gatggcgata
    37681 tcgtcatcac cggcgttgcg tccatgcaat ctgcacaaac aggtcacatt acgttcatgg
    37741 ttaacccaaa ataccgtgag catttaggct tgtgccaggc gtccgcggtt gtcatgaccc
    37801 aggacgatct tcctttcgcg aaaagtgccg cgctggtagt gaagaatccc tacctgactt
    37861 acgcgcgcat ggcgcaaatt ttagatacca cgccgcagcc cgcgcagaac attgcaccca
    37921 gtgcggtgat tgacgcgacg gcgaagctgg gtaacaacgt atcgattggc gctaacgcgg
    37981 tgattgagtc cggcgttgaa ctgggcgata acgtgattat cggtgccggt tgcttcgtag
    38041 gtaaaaacag caaaatcggt gcaggttcgc gtctctgggc gaacgtaacc atttaccatg
    38101 agatccagat cggtcagaat tgcctgatcc agtccggaac agtggtaggc gcagacggct
    38161 ttggttatgc caacgatcgt ggtaactggg tgaagatccc acagattggt cgggtaatta
    38221 ttggcgatcg cgtggagatc ggtgcctgca ctactattga tcgtggcgcg ctggatgaca
    38281 ctgttattgg caatggtgtg atcattgata accagtgcca gattgcacat aacgtcgtga
    38341 ttggcgacaa tacggcagtt gccggtggcg tcattatggc gggcagcctg aaaattggtc
    38401 gttactgcat gatcggcgga gccagcgtaa tcaacgggca tatggaaata tgcgacaaag
    38461 tgacggttac gggcatgggt atggtgatgc gtcccatcac tgaaccaggc gtctattcct
    38521 caggcattcc gctgcaaccc aacaaagtct ggcgcaaaac cgctgcactg gtgatgaaca
    38581 ttgatgacat gagcaagcgt ctgaaatcgc ttgagcgcaa ggttaatcaa caagactaac
    38641 gttccatctt ttgttcgcca aactttacgg cctgtctcat tcttacgatt gcggcaggcc
    38701 gtgttattat tgtcgtttct tatattttga caggaagagt atcttgacta ctaacactca
    38761 tactctgcag attgaagaga ttttagaact tctgccgcac cgtttcccgt tcttactggt
    38821 ggatcgcgtg ctggattttg aagaaggtcg ttttctgcgc gcagtaaaaa atgtctctgt
    38881 caatgagcca ttcttccagg gccatttccc tggaaaaccg attttcccgg gtgtgctgat
    38941 tctggaagca atggcacagg caacaggtat tctggcgttt aaaagcgtag gaaaactgga
    39001 accgggtgag ctgtactact tcgccggtat tgacgaagcg cgctttaagc gcccggtcgt
    39061 gcctggcgat caaatgatca tggaagtcac tttcgaaaaa acgcgccgcg gcctgacccg
    39121 ttttaaaggg gttgctctgg tcgacggtaa agtagtttgc gaagcaacga tgatgtgtgc
    39181 tcgtagccgg gaggcctgat acgtgattga taaatccgcc tttgtgcatc caaccgccat
    39241 tgtggaagag ggcgcgtcga ttggcgcgaa cgctcacatt ggtccttttt gtatcgttgg
    39301 accccatgtc gaaattggtg agggtaccgt actgaaatct cacgttgtcg tgaatggtca
    39361 tactaaaatt ggccgcgata atgagattta tcagttcgcc tccatcggcg aagttaacca
    39421 ggatctgaaa tatgctggcg aaccgacccg cgtggaaatc ggcgatcgta accgcattcg
    39481 cgaaagcgtc accattcatc gtggcacagt ccagggcggt ggattgacga aggtgggcag
    39541 cgacaactta ctgatgatca acgcgcacat tgcgcacgat tgtacggtag gtaaccgctg
    39601 catcctcgcc aacaacgcaa cgctggcggg tcacgtatcg gttgacgact tcgcgatcat
    39661 cggcggcatg accgcagtcc atcagttctg catcattggt gcgcatgtga tggttggcgg
    39721 ctgctccggt gtggcgcagg acgtccctcc ttatgtcatt gcgcagggta accacgcaac
    39781 gccgttcggt gtcaatatcg aagggctgaa gcgccgcgga ttcagccgtg aggcgattac
    39841 cgctatccgc aatgcgtata agctgattta tcgtagcggt aagacgctcg atgaagtgaa
    39901 accggaaatt gctgaactgg cggaaacata tccggaagtg aaagccttta ccgatttctt
    39961 tgcacgctca acgcgcggtc tgattcgtta atgactgaac agcgtccatt aacgattgcc
    40021 ctggtcgccg gagaaacctc cggcgatatc ctgggggccg gtttaatccg cgctctgaaa
    40081 gaacgtgtgc ccaacgcccg ctttgttggt gttgccgggc cacgaatgca ggctgaaggc
    40141 tgcgaagcct ggtacgaaat ggaagaactg gcagtgatgg gcattgttga agtgctcggt
    40201 cgtctgcgtc gcttactaca tattcgtgcc gatctgacaa agcgttttgg cgaactgaag
    40261 ccagatgttt ttgttggtat tgatgcgcct gacttcaata ttactcttga aggtaacctc
    40321 aaaaagcagg gtatcaaaac cattcattac gtcagtccgt ccgtctgggc gtggcgacag
    40381 aaacgcgttt tcaaaatagg catagccacc gatctggtgc tcgcatttct gcctttcgaa
    40441 aaagcgtttt atgacaaata caacgtaccg tgccgcttta tcggtcatac catggctgat
    40501 gccatgccat tagatccaga taaaaatggt gcccgtgatg tgctggggat cccttacgat
    40561 gcccactgtc tggcattgtt gccgggcagc cgtggtgcag aagtcgaaat gcttagtgcc
    40621 gatttcctga aaacggccca gcttttgcgc cagacatatc cggatctcga aatcgtggtg
    40681 ccgctggtga atgccaaacg ccgtgagcag tttgaacgca tcaaagctgc agtcgcgcca
    40741 gacctgtcgg ttcatttgct ggatggaatg ggccgtgagg cgatggtcgc cagtgatgcg
    40801 gcgctactgg cgtcgggtac ggcagcactg gagtgtatgc tggctaaatg cccgatggta
    40861 gtgggatatc gcatgaagcc tttcaccttc tggctggcga agcgactggt gaaaactgat
    40921 tatgtctcgc tgccaaatct gctggcgggc agagagttag tcaaagagtt attgcaggaa
    40981 gagtgtgagc cgcaaaaatt ggctgcggcg ctgttaccgc tgttggcgaa cgggaaaacc
    41041 agccatgcga tgcacgacac cttccgcgag ctgcatcagc agatccgctg caatgccgat
    41101 gagcaggcgg cacaagccgt tctggagtta gcacaatgat cgaatttgtc tatccgcaca
    41161 cgcagctggt tgcgggtgtg gatgaagtcg gacgcgggcc gttagttggc gcggtcgtca
    41221 ccgctgcggt gatccttgac ccggcgcgcc cgattgccgg gctgaatgat tccaaaaagc
    41281 tgagcgaaaa acgccgtctg gcgctctgtg aagagatcaa agagaaagcg ttgagctgga
    41341 gtctgggccg cgcggaacct cacgaaatcg acgaactgaa tattttacat gcgaccatgc
    41401 tggcgatgca gcgtgccgtc gctggactgc atattgcgcc ggaatatgtg ttgattgatg
    41461 gtaaccgctg cccgaaatta ccgatgcctt cgatggctgt ggtgaaaggc gatagccgcg
    41521 taccggaaat cagtgccgcg tctatcctgg cgaaagtgac gcgtgacgcc gaaatggcgg
    41581 cgctggatat tgttttcccg caatatggtt ttgcccaaca caaagggtat ccaaccgctt
    41641 ttcatctgga aaaactggct gaacacggcg cgaccgaaca ccatcggcgc agctttgggc
    41701 ctgtcaaacg cgcactggga cttgcgtcct gattcttgtg tcgagattaa gtaaaccgga
    41761 atctgaagat gtctgaacca cgtttcgtac acctgcgggt gcacagtgac tactcgatga
    41821 tcgatggcct ggccaaaacc gcaccgctgg taaaaaaggc ggcagcgttg ggtatgccag
    41881 cactggcgat caccgatttc accaaccttt gcggtctggt gaagttctac ggagcgggac
    41941 atggcgcagg gattaagccc atcgtcgggg cggattttaa cgtccagtgc gacctgctgg
    42001 gtgatgagtt aactcacctg acggtgctgg cggcgaacaa taccggctat cagaatctga
    42061 cgttgctgat ctcaaaagcg tatcagcgcg ggtacggtgc cgccgggccg atcatcgatc
    42121 gcgactggct tatcgaatta aacgaagggt tgatccttct ttccggcggg cgcatgggcg
    42181 acgttggacg cagtcttttg cgtggtaaca gcgcgctggt agatgagtgt gtcgcgtttt
    42241 atgaagaaca cttcccggat cgctattttc tcgagctgat ccgcaccggc aggccggacg
    42301 aagaaagcta tctgcacgct gcggtggaac tggcggaatc acgcggtttg cccgttgtgg
    42361 cgaccaacga cgtgcgcttt atcgacagca gcgactttga cgcacacgaa atccgcgtcg
    42421 cgatccacga cggctttacc ctcgacgatc ctaaacgccc gcgtaactat tcgccgcagc
    42481 aatatatgcg tagcgaagag gagatgtgcg agctttttgc cgacattccc gaagcccttg
    42541 ccaacaccgt tgagatagcc aaacgttgta acgtaactgt gcgtctgggt gaatacttct
    42601 tgccgcaatt cccgaccggg gacatgagta ccgaagatta tctggtcaag cgtgcaaaag
    42661 aaggcctgga agagcgtctg gcatttttat tccctgacga ggaagaacgt cttaagcgtc
    42721 gtccggagta tgacgaacgt ctggatactg aacttcaggt tatcaaccag atgggcttcc
    42781 cgggttactt cctcatcgtt atggaattta tccagtggtc gaaagataac ggtgtaccgg
    42841 tagggccagg ccgtggttct ggtgcagggt cactggtggc ctacgcgtta aaaatcaccg
    42901 atctcgatcc gctggaattt gacctgctgt tcgaacgttt ccttaacccg gaacgtgtct
    42961 ccatgcctga cttcgacgtt gacttctgta tggagaaacg tgaccaggtt atcgaacatg
    43021 tggcggacat gtacggtcgc gatgcggtat cgcagattat caccttcggt acgatggcgg
    43081 cgaaagcggt gatccgcgac gtaggccgtg tattggggca tccgtacgga tttgtcgatc
    43141 gtatctcgaa actgatcccg cccgatccgg gtatgacgct ggcgaaagcg tttgaagccg
    43201 agccgcagct gccggaaatc tacgaagcgg atgaagaagt taaggcgctg atcgacatgg
    43261 cgcgcaaact ggaaggggtc acccgtaacg ccggtaagca cgccggtggg gtggttatcg
    43321 cgccgaccaa aattactgat tttgcgccgc tttattgcga tgaagagggc aaacatccgg
    43381 tcacccagtt tgataaaagc gacgttgaat acgccgggct ggtgaagttc gacttcctcg
    43441 gtttgcgtac gctcaccatc atcaactggg cgctggagat gatcaacaag cggcgggcga
    43501 agaatggcga gcccccgctg gatatcgccg cgatcccgct ggatgacaag aaaagcttcg
    43561 acatgctgca acgctcggaa accacggcgg tattccagct tgaatcgcgc ggcatgaaag
    43621 acctgatcaa gcgtctgcaa cctgactgct tcgaagatat gatcgcactg gtggcactgt
    43681 tccgccccgg cccgttgcaa tcagggatgg tggataactt tatcgaccgt aaacatggtc
    43741 gcgaagagat ctcctatccg gacgtgcagt ggcagcatga aagcctgaaa ccggtactgg
    43801 agccaaccta cggcatcatc ctgtatcagg aacaggtcat gcagattgcc caggtgcttt
    43861 ctggttatac cctcggtggc gcggatatgc tgcgtcgtgc gatgggtaag aaaaagccgg
    43921 aagagatggc taagcagcgt tctgtatttg ctgaaggtgc agaaaagaac ggaatcaacg
    43981 ccgaactggc gatgaaaatc ttcgacctgg tggagaaatt cgcgggttac ggatttaaca
    44041 aatcgcactc ggcggcctat gctttggtgt catatcaaac gttatggctg aaggcacatt
    44101 atccggcaga gtttatggcg gcggtaatga ccgccgatat ggacaacacc gagaaggtgg
    44161 tgggcctggt ggatgagtgc tggcggatgg ggctgaaaat cctgccacca gatataaact
    44221 ccggtcttta ccatttccac gtcaacgacg acggcgaaat cgtgtatggt attggcgcga
    44281 tcaaaggggt aggtgaaggc ccgattgagg ccatcatcga agcccgtaat aaaggcggct
    44341 acttccgcga actgtttgat ctctgcgccc gtaccgacac caaaaagtta aaccggcggg
    44401 tgctggaaaa actgatcatg tccggggcgt ttgaccgtct tgggccacac cgcgcggcgc
    44461 tgatgaactc gctgggcgat gcgttaaaag cggcagatca acacgcgaaa gcggaagcta
    44521 tcggtcaggc cgatatgttc ggcgtgctgg ccgaagagcc ggaacaaatt gaacaatcct
    44581 acgccagctg ccaaccgtgg ccggagcagg tggtgttaga tggggaacgt gaaacgttag
    44641 gtctgtacct cacgggacac cctatcaacc agtatttaaa agagattgag cgttatgtcg
    44701 gaggcgtaag gctgaaagac atgcacccga cagaacgtgg taaagtcatc acggctgcgg
    44761 ggctcgttgt tgccgcgcgg gttatggtca ccaagcgcgg caatcgtatc ggtatctgca
    44821 cgctggatga ccgttccggg cggctggaag tgatgttgtt tactgacgcc ctggataaat
    44881 accagcaatt gctggaaaaa gaccgcatac ttatcgtcag cggacaggtc agctttgatg
    44941 acttcagcgg tgggcttaaa atgactgctc gcgaagtgat ggatattgac gaagcccggg
    45001 aaaaatatgc tcgcgggctt gctatctcgc tgacggacag gcaaattgat gaccagcttt
    45061 taaaccgact ccgtcagtct ctggaacccc accgctctgg gacaattcca gtacatctct
    45121 actatcagag ggcggatgca cgcgcgcgat tgcgttttgg cgcgacgtgg cgtgtctctc
    45181 cgagcgatcg tttattaaac gatctccgtg gcctcattgg ttcggagcag gtggaactgg
    45241 agtttgacta atacaggaat actatgagtc tgaatttcct tgattttgaa cagccgattg
    45301 cagagctgga agcgaaaatc gattctctga ctgcggttag ccgtcaggat gagaaactgg
    45361 atattaacat cgatgaagaa gtgcatcgtc tgcgtgaaaa aagcgtagaa ctgacgcgta
    45421 aaatcttcgc cgatctcggt gcatggcaga ttgcgcaact ggcacgccat ccacagcgtc
    45481 cttataccct ggattacgtt cgcctggcat ttgatgaatt tgacgaactg gctggcgacc
    45541 gcgcgtatgc agacgataaa gctatcgtcg gtggtatcgc ccgtctcgat ggtcgtccgg
    45601 tgatgatcat tggtcatcaa aaaggtcgtg aaaccaaaga aaaaattcgc cgtaactttg
    45661 gtatgccagc gccagaaggt taccgcaaag cactgcgtct gatgcaaatg gctgaacgtt
    45721 ttaagatgcc tatcatcacc tttatcgaca ccccgggggc atatccgggc gtgggcgcag
    45781 aagaacgtgg tcagtcggaa gccattgcac gcaacctgcg tgaaatgtct cgcctcggcg
    45841 taccggtagt ttgtacggtt atcggtgaag gtggttctgg tggtgcgctg gcgattggcg
    45901 tgggcgataa agtgaatatg ctgcaataca gcacctattc cgttatctcg ccggaaggtt
    45961 gtgcgtccat tctgtggaag agcgctgaca aagcgccgct ggcggctgaa gcgatgggta
    46021 tcatcgctcc gcgtctgaaa gagctgaaac tgatcgactc catcatcccg gaaccgctgg
    46081 gcggtgctca ccgtaacccg gaagcgatgg cggcgtctct gaaagcgcag ctgctggcgg
    46141 atctggccga tctcgacgtg ttaagcactg aagatttaaa aaatcgtcgt tatcagcgcc
    46201 tgatgagcta cggctacgcg taatcggcaa atgttctgaa aagggtcact tcggtggccc
    46261 ttttttatcg ccacggtttg agcaggctat gattaaggaa ggattttcca ggaggaacac
    46321 atgaacatca ttgccattat gggaccgcat ggcgtctttt ataaagatga gcccatcaaa
    46381 gaactggagt cggcgctggt ggcgcaaggc tttcagatta tctggccaca aaacagcgtt
    46441 gatttgctga agtttatcga acataaccca cgaatttgcg gcgtgatttt tgactgggat
    46501 gagtacagtc tcgatttatg tagcgatatc aatcaactta atgaatatct cccgctttat
    46561 gccttcatca acacccactc gacgatggat gtcagcgtgc aggatatgcg gatggcgctc
    46621 tggttttttg aatatgcgct ggggcaggcg gaagatatcg ccattcgtat gcgtcagtac
    46681 accaacgaat atcttgataa cattacgccg ccgtttacga aagccttgtt tacctacgtc
    46741 aaagagcgga agtacacctt ttgtacgccg gggcatatgg gcggtaccgc atatcaaaaa
    46801 agcccggttg gctgtctgtt ttatgatttt ttcggcggga ataccctcaa ggcggacgtc
    46861 tctatttcgg tcaccgagct tggttcgttg ctcgaccaca ccgggccaca cctggaagcg
    46921 gaagagtaca tcgcgcggac gtttggcgcg gaacagagtt atatcgttac taatggaaca
    46981 tcgacgtcga acaaaattgt gggtatgtac gccgcgccat ccggcagtac gctgttgatc
    47041 gaccgcaatt gtcataaatc gctggcgcat ctgttgatga tgaacgatgt agtgccagtc
    47101 tggctgaaac cgacgcgtaa tgcgttgggg attctgggtg ggatcccgcg cggtgaattt
    47161 actcgcgaca gcatcgaaga gaaagtcgct gccaccacgc aggcacaatg gccggttcat
    47221 gcggtgatca ccaactccac ctatgatggc ttgctctaca acaccgactg gatcaaacag
    47281 acgctggatg tcccgtcgat tcacttcgat tctgcctggg tgccgtacac ccattttcat
    47341 ccgatctacc agggtaaaag tggtatgagc ggtgagcgtg ttgcgggaaa agtgatcttc
    47401 gaaacgcagt cgacccacaa aatgctggcg gcgttgtccc aggcgtcgct gatccacatt
    47461 aaaggcgagt atgacgaaga ggcgtttaac gaagccttta tgatgcatac caccacctcg
    47521 cccagttatc ccattgttgc ttcggttgag acggcggcgg cgatgctgcg tggtaatccg
    47581 ggcaaacggc tgattaaccg ttcagtagaa cgagcgctgc attttcgcaa agaggtccag
    47641 cggctgcggg aagagtctga cagctggttt ttcgatatct ggcaaccgcc gcaggtggat
    47701 gaagccgaat gctggcacgt tgcgcctggc gaacagtggc acggctttag cgatgcggat
    47761 gccaatcaca tgtttctcga tccggttaaa gtcactattt tgacaccggg aatggacgag
    47821 cagggcaata tgagcgagga ggggatcccg gcggcgctgg tggcaaaatt cctcgacgaa
    47881 cgtgggatcg tagtagagaa aaccggccct tataacctgc tgtttctctt tagtattggc
    47941 atcgataaaa ccaaagcaat gggattattg cgtgggttga cggaatttaa gcgctcttac
    48001 gatctcaacc tgcggatcaa aaatatgctg cccgatctct atgcagaaga tcccgatttc
    48061 taccgcaata tgcgtattca ggatctggcg caagggatcc ataagctgat tcgtaaacac
    48121 gatcttcccg gtttgatgtt gcgggcattt gataccttgc cggagatgat catgacgcca
    48181 catcaggcat ggcagagaca gattaaaggc gaagtagaaa ccattgcgct ggaacaactg
    48241 gtcggtagag tatcggcaaa tatgatcctg ccttatccac ccggcgtacc gctgctgatg
    48301 ccgggagaaa tgcttaccga agagagccgc acggtactcg attttctact gatgctttgt
    48361 tccgtagggc aacattaccc cggttttgaa acggatattc acggcgcgaa acaggacgaa
    48421 gacggcgttt accgcgtacg agtcctaaaa atggcgggat aacttgccag agcggcttcc
    48481 gggcgagtaa cgtgctgtta acaaataaag gagacgttat gctgggttta aaacaggttc
    48541 accatattgc gattattgcg acggattatg cgatgagcaa agctttctac tgcgatattc
    48601 ttggtttcac gctgcaaagc gaagtctatc gcgaagcgcg cgactcgtgg aaaggggatt
    48661 tggcgcttaa tgggcaatat gtgattgagc ttttctcatt tccgttcccg ccggagcgcc
    48721 ccagccgacc ggaagcttgc ggcctgcgtc atctggcttt tagcgttgat gatatcgatg
    48781 cggcagtggc gcaccttgaa agccataacg tgaagtgtga agccatccgt gtcgatccat
    48841 acacgcaaaa acgcttcacg ttctttaacg atccggacgg gctgccgttg gaactgtatg
    48901 agcagtaagg cttgtcatcg ccgcatttgc ccggtaacgt gccgggcatt gctactgtaa
    48961 aatcgcacca tcatgacact cacgctcaat agacaacttc tctcctcacg ccagattctg
    49021 gtggccttta gcggcggcct tgattctact gtcttactgc atcaactggt gcagtggcgg
    49081 acggaaaatc cgggcgtcac tctgcgcgct atccatgtgc atcacggttt aagcgccaat
    49141 gctgatgcct gggtgaaaca ttgtgaaaac atctgccaac agtggcaggt gccgctggtg
    49201 gtcgaacgtg tgcagcttgc gcaagagggg ctaggtattg aggcccaggc gcggcaggca
    49261 cgttatcagg catttgcccg taccttgttg cccggtgaag tgctggttac agcgcaacat
    49321 ctcgacgatc aatgtgaaac ctttctgctg gcgctaaaac gcggtagcgg ccctgccggg
    49381 ctttcggcta tggcggaagt ttcggagttt gccggaacac ggcttatccg cccgttgctt
    49441 gcccgcacgc ggggggaact ggagcagtgg gcgcgtcagt atgatttacg ctggattgaa
    49501 gacgaaagta atcaagacga ttcctacgat cgtaacttct tgcgcctgcg cgtagtgccg
    49561 ttattgcagc agcgttggcc gcattttgcc gaagcgacgg cccgcagcgc cgcactttgc
    49621 gccgaacaag agagcctgct ggatgaactg ctggcggatg atttagcgca ctgccaaacg
    49681 caacagggaa cgttaaagat tgcgccaatg ctggcaatga gcgatgcccg tcgcgcggcg
    49741 attatccgcc gctggctggc agggcagaat gcacctatgc cttcccgcga ggcgctggtg
    49801 cggatctggc aggaagtggc gctggcgcgg gaagatgctt ccccctgttt acgtttgggc
    49861 gcgtttgaaa tccgccgcta tcagtcgcaa ctgtggtgga ttaaatccgt tgccgggcaa
    49921 agcgaaacca ttgtgccgtg gcagacgtgg ctacaaccgc tggaattacc ggcggggctg
    49981 ggaagtgtac agcttactgc gggaggcgat attcgccctc cgcgtgcaga cgaagcggtc
    50041 agcgtgcgtt tcaaagcgcc aggactgctg catattgtcg ggcgcaacgg tggacgtaag
    50101 ctgaagaaaa tctggcaaga gttaggcgtt ccgccgtggc tacgtgacac cacgccactg
    50161 ctgttttatg gcgaaacgct gattgcggcg gcaggggtat ttgtgacgca agaaggtgtg
    50221 gctgtaggtg agaatggcgt cagttttgtc tggcagaaaa cgcttagtca agtgaaagcc
    50281 ggataagacg catcaaacgt cgcatccggc gaaagtcaat caggactcgc tcaccaccac
    50341 cgtaccgatt tccgggtggc taaagctggt aattttatcc agacgcagct cgcgggttgc
    50401 accagcggcc tcgacgacca gatactccac atttttgcgg gagactaaat cgctggcctt
    50461 cgcctgcaat ttttcgccat ctttcagctc aagtgtcagc attaaatgat gctggcaggc
    50521 gagctcaaga ttatcgtaat catcacaatt gattggttga tacgtatcat tcattgacat
    50581 aatcgctcac cagtaagttt gccgcagcgt atgctgcttt ttccctgaca gcctcagaaa
    50641 gggcgtcgtc ggcagccatt tcattcagca ctttcaaaac gcagcccagc gcgtccggaa
    50701 cgtatcctaa gtctccgctg gcgatttccg cgtaccgctt gcgtattaac tcacaatatt
    50761 tttccacatg ccctcctgtc agcactctga cttaaccgtg gatgcaagtc taagcctacg
    50821 aagataaact ctgtttcgca aggtgactat accacactca tttctgcaat atcagcgccg
    50881 caactgcacg tattccgtta caatggcctc ctgattcgaa aggagttttc ttatggcgct
    50941 taaagcgaca atttataaag cgacggttaa tgtggccgat ctcgaccgca accagtttct
    51001 cgatgcctct ctgacgttgg cgcgccatcc ttcagaaacc caggagcgta tgatgctgcg
    51061 cctgctggcg tggctaaaat atgccgatga acgtctgcaa tttacccgtg gtttgtgtgc
    51121 cgatgatgag ccggaagcgt ggctgcgtaa cgatcatttg ggtattgatt tgtggattga
    51181 gctggggctg ccggatgagc gacggattaa gaaagcctgc acccaggccg cagaagtggc
    51241 gctgtttgcc tataatagtc gggcggcgca aatctggtgg cagcaaaatc agagcaaatg
    51301 tgcgcagttt gccaatcttt ccgtctggta tctggacgac gagcagctgg cgaaagtgag
    51361 cgcctttgcc gatcgtacca tgacgctgca ggcaacgatt caggatggtg ttatctggtt
    51421 atcggatgat aagaataatc tggaagtgaa cttaaccgtc tggcaacaac cttcatgatt
    51481 gtgatttccc gacatgttgc tatccctgat ggcgagtttg agatcaccgc cattcgtgcg
    51541 cagggcgcgg gcgggcagca tgttaataag acctcaacgg ctattcatct gcgttttgac
    51601 attcgggcgt ccagcctgcc agagtattac aaagagcgtc tgctcgccgc cagccatcat
    51661 ttgatcagca gtgacggagt gattgtcatt aaggcacagg aataccgcag tcaggaactg
    51721 aaccgcgaag cggcgctggc ccggctggtg gcagtgatta aagatttaac aacagaacaa
    51781 aaagcccgaa gacctacgcg gcccacccgt gcatcgaaag agcgcaggct ggcatcgaaa
    51841 gcacaaaaat caagcgtgaa ggcgatgcgc ggcaaagtgc gcagcggtcg ggagtaaaaa
    51901 gaaggaatgg atggtgaaaa aagcgatagt gacagcgatg gctgtaatca gcctttttac
    51961 tctgatggga tgtaataatc gggccgaagt cgatacgctt tccccggcgc aggctgccga
    52021 actgaaaccg atgccgcaaa gttggcgcgg cgtgctgccg tgtgctgatt gcgaaggaat
    52081 cgaaacctct ctgttcctcg aaaaagatgg aacctgggtg atgaatgaac gttatctggg
    52141 ggcacgtgaa gagccttcct ctttcgcttc ctacggtaca tgggcgcgaa ctgccgacaa
    52201 gctggtatta accgacagca aaggtgaaaa gtcatattat cgagcgaaag gggatgcact
    52261 ggagatgctc gatcgtgaag gtaatcccat tgaatcgcag ttcaactaca cgctggaacc
    52321 ggcaaaatcg agcatgccaa tgacgccgat gaccctgcgt ggcatgtatt tctatatggc
    52381 tgatgcggcg acctttactg attgcgcgac tggaaaacgt tttatggtgg cgaataacgc
    52441 agagctggag cgtggctacc tggctgcgcg cggcaacggc gaaaaaccgg tgttactgtc
    52501 agtagaaggt cactttacgc ttgaggctaa tccggatacc ggtgcgccga ccaaagtatt
    52561 agcgcccgat acggcaggta aattttaccc gaaccaggat tgcagtagtt tggggcagta
    52621 acccgtcttg aggcagaaac aaatgaaata ttgcctcatg cgctgcgctt atcaggccta
    52681 aagcatacaa tgcaatattt tgaattagca cgattttgta ggccggataa ggcgttcacg
    52741 ccgcatccgg cattttgcgc acgaggctgg cttttatcac tgagtcagtc caacaaagcg
    52801 acttgcttta atataaatcc ctggcttcag gtgcccaata tactgtaact gcgtttctgg
    52861 tttaaatgca gagacatcac cactacgcat atgcatcaga tcggcagggc taatccagcc
    52921 tgattgcgcc agcgtaagcg gatgcccggc tttggcaaat gcatccgtga caaattccga
    52981 acaaaaccac gactttttgt ctccttcgcc aacgttactt aactgcgctt tcgccaggcc
    53041 gctgacgcac tgttggcgaa aatcctcgga gaacggattc agtgagcaca tctggcgagt
    53101 caccataaat ggaataaatt cgacaatgcc gcgatagtta taaccgctat ctttaatttt
    53161 attggcgaac gcggtgattt ctgtggcttg ttgcggggta aggtccggga ctcgtaagac
    53221 gaaaagctta tcactgtgct tcatggcttt tttaagggaa acaatctgga cgccagcgcc
    53281 tgtcgcttcg gcaacgttat tatttcccaa atagattgca acgtgactca cagaggaagt
    53341 gctgaatacg cggataccaa atgaggttac cccaaggctt gaggagaaaa gcaaatcgcc
    53401 gggtttgaga tctggttccg ttatttcttt tattgattgt tcggtgaaag agctttgatg
    53461 ctggaattta acagcccatg ttttcgcctc ggcatttacc gctgtggctg atgagtctgg
    53521 ctggctgata tcaacggtac aggccgaaag taaaagaaag caggggagaa gcaggcggca
    53581 gtacgccttt ggtttatcca ttttatacaa tccatgtaaa aaagggcccc gaaattcagg
    53641 accctttctg gcatcagcct ttaatctgtt tcaccagata atcgacgatg tcaccagtct
    53701 taattaactg tttctcgccg ttacgacgat atttatattc gatatcatcg ttgtcgaggt
    53761 tacggtcgcc cagcacaata gtgtgcggaa taccgatcag ttccatatca gcaaacatca
    53821 cgcccggacg ctctttgcgg tcatccagca gcacttcgat accttgtgcg cgcagttcgc
    53881 tgtacagttt ctcagcaagt tcctgtacgc ggaaggattt gtgcatgttc attggcagaa
    53941 tcgccacctg gaacggcgcg atagcgtcag gccatacgat gccgcgttcg tcgtagttct
    54001 gctcaatcgc cgctgctacc acacgcgtta cgccgatacc gtagcaaccc atcgtcagga
    54061 tttggttacg gccatcttca ccctgtacgg aggctttcag tgcttcggag tacttggtac
    54121 ccagctggaa gatgtgaccg acttcgatac cacgtttgat cagcagcgta ccctgaccat
    54181 ccgggcttgg atcgccagcc accacgttgc ggatatcagc aatttccggg gtagcgacat
    54241 cgcgatccca gttgataccg aagtagtgtt taccatcgat gttagcacca gcagcgaaat
    54301 cactcatcgc cgcaacggta cggtcaatca ccaccggaat cggcatgttt accggaccca
    54361 gtgaacccgg accggcttta accacggcac gaatttcttc ttcggtcgca aaagtcagcg
    54421 ggctggcaac ctgcggcagt ttttctgctt taacttcgtt cagctcgtgg tcaccgcgca
    54481 ccagcagcgc aaccagcggg aagctactgc cttcaacggc tttaaccagc agagtcttaa
    54541 ccgttttctc aatcggcaga ttgaactgtt caaccagttc cgcgatggtt ttcgcgttcg
    54601 gcgtatcaac cagcgtcatt tcctgggtag cagcagcgcg cggttctttc ggcgcgatag
    54661 cttctgccag ttcaatgttc gctgcgtagt cagaagtatc ggagaagacc acatcgtctt
    54721 caccgctctg cgccagcacc tgaaattcgt gagaggcgct accgccgata gaaccggtat
    54781 cggcctgtac ggcgcggaaa tccagcccca tgcggctgaa gattttgctg taggccgcat
    54841 acattgcatc gtaggtttcc tgcagggatt cctgagaagt atggaaagag taagcatctt
    54901 tcatcaggaa ttcgcgggaa cgcatgacgc caaaacgcgg acgcacttcg tcgcggaact
    54961 tggtctggat ctgatagaag ttcagcggca gttgtttgta agagctcagc tcgttacgaa
    55021 tcaggtcagt gataacttct tcatgagttg ggccgagtac gaacggacgc tcgccacggt
    55081 caacaaaacg cagcagttcc ggaccgtact gttcccaacg accactctct tgccacaaat
    55141 cggctggctg aaccaccggc attaacacct cgatcgcacc ggcgttgttc atctcttcac
    55201 gcacgatgtt ttcgactttt ttcagaacgc gcacgccggt cggcagccag gtatataacc
    55261 cggaggccag cttgcggatc atcccggcgc gcagcatcag ctgatggctg atcacctcgg
    55321 cgtcggcagg tgtctccttg agagtggaga gcaggtattg gctagtacgc atgttgttac
    55381 ggttccagtt ggaaggtaga acaggctcaa ggcgagcctg ggacaaaaaa agtgatttag
    55441 tttaccagtg caaaagaaat gtcaaaagag aagggcgtga atttaacgcg gttccagcgc
    55501 aaagacttca aaacctgcgt cggtgacgcg ccagcgaacg ttaaaatcat gcaaccagac
    55561 ggcataggtt ttgcccgttt cctcaccttt acgataggcc gggcgcgggt cctgcgccag
    55621 tacttcgcgg ataaacagcg ttaactgcgg ataacgcttc tccagcgtca aaagctgctt
    55681 ttcgacctct gcggtaaaac aaaccgccat ttctgccgct ggcgcacttt gcgcatagct
    55741 ggcactggca tcgggaagcg attcagcaaa ggggagatac ggtttgatat ccactaccgg
    55801 cgtaccatcg accagatcca gactgccgag cttcagaatc acgctgtctt tatggcaaac
    55861 aacctctttc agctctacca gcgacatacc aatcgggttg gggcgaaaag tggagcgcgt
    55921 agcgaaaaca cccattctgg cattaccgcc gagacgaggc ggacgcacag tcggacgcca
    55981 gccgccttcc atcgtttgat gaaagacgaa aaggatccat aaatggctga atgcttccag
    56041 gccgcgaacg gcgtcggcct ggttgtaggg agcaatgaga tgtagttcgc cgttggcgct
    56101 ttttaccaga cctggctggc gcggaacggc gaatttttct ttatagggcg agcgaataac
    56161 gcctatttgc tcgaactgga aactgctcat ttcgccgtga tgttaagcgc agaaccgata
    56221 catacagcct gacgatagca acctggcgta ccgctggtga cttcgcagct atgcagtaat
    56281 accgcattgg ctttcatttt cgaggcgttg atttgcatcc gcttacgtgc ggttggaatg
    56341 ctcggcggag agtcctgatt agaggcctgg caagagtcgc cactgacttc accgagatcg
    56401 cggaacggtt tgccgactaa ttcttctgca ttggtataaa ttcggaccgg cgtggcgcgc
    56461 ggcgctttcg gttttgcagg ctccgctttc ggctggggtg cagtgctttg aacgggttcg
    56521 acaggggatc tgcttaacat ggaacagccg cttagcatga gtgctactaa acagatcggt
    56581 aaagcacgca tagtatttcc tcaatgtatg atcaaaacgt caatattgaa tcaggcgctt
    56641 gtaaaaatga caagacgggc aagcgcccgt cctgaatgat attacaaatt gtggaaacag
    56701 cctaaatatt accagccttt aacagcgccg ccgttaaaca ctttgtttgc tgcttcgtaa
    56761 acttcgtcag actgataagc ctgaacgaat ttcttcacgt tttcggcgtc tttgttgtct
    56821 tcacgcgtta cgatcaggtt tacgtacggg gactctttat cttcgacaaa gataccgtct
    56881 ttcgctggag tcaggccaat ctggctggca taggtggtat tgataactgc cagagcgatt
    56941 tgcgcgtcgt ccagagagcg cggcagctgc ggtgcttcca gttcaacaat tttcagattt
    57001 tttgggttct caacaacatc aagaacggtc ggcagcaggc caacgccatc tttcagtttg
    57061 atcaagccca ctttttgcag cagcagcagt gaacgaccaa ggttagttgg gtcgtttggc
    57121 acggcaacct gcgaaccatc ctgcagttca tccagtgatt tgattttctt ggagtaacca
    57181 gcaatcggat aaacaaatgt gttgcctact gcgaccagtt tgtagccacg atctttcagt
    57241 tgctgatcaa ggtacggttt atgctggaag gcgttggcgt cgatatcgcc tttgctcaat
    57301 gcttcgtttg gcagaacata gtcgttgaag gttaccagct caacgtccag gccatatttg
    57361 tctttcgcaa ctttctgcgc gacttctgca acctgctgtt cggcaccaac aatcacgccg
    57421 actttaatgt ggtttggatc tttttcatcc tgaccgcagc ctaccagtgc cagtgatcca
    57481 atcagggctc ccactgccgc aaaggttttg aatttgaacg ccatacctta ttccttcttc
    57541 aattatttat gttgtgttga acgttacttg cgagtgacag cccggacgat gcggtcgcct
    57601 gcgaactgaa ttaaataaac cagaatgacc agcaatacca gtaccgtatt catcaccgtc
    57661 gcgttgtagc cgatgtagcc atactgatag ccaatctgac ctaaaccacc ggcaccgact
    57721 gcaccaccca tcgcggaata accgaccagg gtaatcaggg taatagttgc cgcattcacc
    57781 agacccggca acgcttccgg taacagcact ttacggacga tctgcattgg cgtggcaccc
    57841 attgcgcggg aggcttcaat taacccggtt gggatctcca gaagagcgtt ctcgaccata
    57901 cgggcaataa acggtgctgc accaacggtt aacggaacaa tcgctgcctg caatccaatc
    57961 gatgtaccga caataacgcg ggtaaacgga atcatccata ccagcaagat aatgaacggg
    58021 atggaacgga aaatgttcac aatcgcagaa atggtacgat acaacttcgc gttagcaata
    58081 atttgccccg gacgcgtgac ataaagcaga acgccaaccg gcagaccaat cacaaagcca
    58141 aaaaaaccgg atacgaaggt cattgccagc gtttcccata cgccacgaac cagcagccac
    58201 atcatcggct cagacataac ccagtacctc tacttttaca tggtgttcct gcagccaggc
    58261 aatggcggct tgcgtatctt gttgtgtgcc gtgcatttca gtcagcataa tgccgaactt
    58321 aacgccaccg gcgtaatcca tctgcgcgct aataatgttg ttgttgacgt tgaaacgacg
    58381 cgcggtttca gaaagcagtg gggcatcgac cgattgaccg gtaaactcca gacgcagcat
    58441 cggcacgcag tcagtaaatg gctccgcttg cagacgttcc tggtaatctt ccgggatatc
    58501 cagatgcagg gtcgactgaa taaacttctg cgccagcggc gttttcggat gcgagaacac
    58561 ttcacttacc gtgtcctgct cgatcagttc gccattgctg atgaccgcca cgcaatcaca
    58621 aatgcgcttc acaacgtcca tttcgtgagt gatcaacaga atcgtcaaac ccagacggcg
    58681 gttgatgtct ttcagcagtt cgagaataga acgtgtcgtt gccgggtcca gcgcgctggt
    58741 ggcttcatca cacagcaata ctttgggatt gctggctaat gcacgggcaa tcgccacacg
    58801 ttgtttctgc ccaccggaaa gattcgacgg gtagctatca tgcttatcgc caagaccaac
    58861 caatgacagc aattccgtca cgcgacgttt gatctcgtct ttcggtgtgt tgtccagctc
    58921 cagcggcaga gccacgttgc caaaaacagt acgcgaagag agcaggttaa aatgctggaa
    58981 aatcatacca atctggcgac gagctttggt caactcggat tctgacagcg tggtcagttc
    59041 ctggccatcg accagcacgc taccctcggt tgggcgctcc agcaggttta cacaacgtat
    59101 aagcgtactc ttacccgcgc ctgaggcacc gataacgcca taaatttgtc cagctggcac
    59161 atgcaggctg acgttgttca acgcctggat ggtgcgggtg ccctggtgga acactttggt
    59221 gatattcgaa agttttatca ttgattattt attatcgtca ttaagttagt cgtggcattt
    59281 cgaatgcctg gaacgggcaa cgccgtcaat gaaatggatg ttaaggcatc cagacgtcta
    59341 aatcaatcag gtttatgcga agagcacttt cttgcaggtc gaaacatgcg atactagcgt
    59401 cacatgcctt attaaggagc tataaaaggt ggcgaagagc gtacccgcaa tttttcttga
    59461 ccgtgatggc accattaatg tcgatcacgg ttatgtccat gagatcgaca actttgaatt
    59521 tatcgacggt gttattgacg ccatgcgcga gctaaaaaaa atgggctttg cgctggtggt
    59581 agtaaccaac cagtctggca ttgctcgcgg taaatttact gaagcacagt ttgaaacgct
    59641 gaccgagtgg atggactggt cgctggcgga ccgcgatgtc gatctggatg gtatctatta
    59701 ttgcccgcat catccgcagg gtagtgttga agagtttcgc caggtctgcg actgccgcaa
    59761 accacatccg gggatgtttt tgtcagcacg cgattatttg catattgata tggccgcttc
    59821 ttatatggtg ggcgataaat tagaagatat gcaggcagcg gctgcggcga gcgtgggaac
    59881 aaaagtgctg gtgcgtacgg gtaaacctat tacgcctgaa gcagaaaacg cggcggattg
    59941 ggtgttaaat agcctggcag acctgccgca agcgataaaa aagcagcaaa aaccggcgta
    60001 atgattaaaa gatgagcggt tgaaataaaa atgcattttt ccgcttgtct tcctgagacg
    60061 actccctata atgcgcctcc atcgacacgg cggatgtgaa tcacttcaca caaacagccg
    60121 gttcggttga agagaaaaat cctgaaattc agggttgact ctgaaagagg aaagcgtaat
    60181 atacgccacc tcgcgacagt gagctgaaag ccgcgtcgca actgctcttt aacaatttat
    60241 cagacaatct gtgtgggcac tcgaagatac ggattcttga cgtcgcaaga cgaa
//
LOCUS       DAFGPF010000016        57531 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFGPF010000016 DAFGPF010000000
VERSION     DAFGPF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57531
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.016"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            166..1425
                     /locus_tag="LSX49_001196"
     CDS             166..1425
                     /locus_tag="LSX49_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBL7167632.1"
                     /translation="MFTNVNVDCCKTPGCKNLGLLNSQDYVAQGKNILCRECGYLFPV
                     ISEQSLNIYRNIVNHSWRGLICQCSTCGGTSLKKYGYSAQGQRRMYCHHCEKTFITLE
                     HVITTPRGAQLALMIEQGEALADIRKSLLLNSTGLSRELLKLAREANYKESRQCFPAS
                     DITLSTRAFRVKYNGSNNSLYALVTAEEQSGRVVAISTNYSPSAVEQHYQYTSNYEER
                     MSPGTLAHHVQRKELLTMRRDTLFDIDYGPAVLHQNDPGMLVKPVLPAYRHFELVRIL
                     TDEHSNNVQHYLDHECFILGGCLMANLQHIHQGRCHISFVKERGVAPATIDFPPRLFL
                     SGGVRNNVWRAFSNRNYSMAVCNLTGSKKVREMRHATLNSATRFIHFVENHPFLISLN
                     RMSPANVVSTLDILKHLWNKKLEHGTI"
     gene            1660..2826
                     /gene="nhaA"
                     /locus_tag="LSX49_001197"
     CDS             1660..2826
                     /gene="nhaA"
                     /locus_tag="LSX49_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HBL7167633.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAVLAMIMANSGATSGWYHDFLET
                     PVQLRVGTLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLEGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     gene            2892..3791
                     /gene="nhaR"
                     /locus_tag="LSX49_001198"
     CDS             2892..3791
                     /gene="nhaR"
                     /locus_tag="LSX49_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HBL7167634.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSSLFSPASR"
     gene            complement(3849..5888)
                     /locus_tag="LSX49_001199"
     CDS             complement(3849..5888)
                     /locus_tag="LSX49_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HBL7167635.1"
                     /translation="MSFIKQDPHRLVWQQDDRYLWIEAWGENSLRVRSGRHLPMMRNE
                     NWALTEEKGDAVAYITYEEKQATLQNGKITAIVNLQGQISFWRNAEKCLLQEFWRQRG
                     EIGEDESAHGQYVSALNLQAREFKPIPGGKYTIKARFEANDGEKLFGMGQYQQPNLDL
                     KGCMLELAQRNSQASVPFLLSNRGYGFLWNNPAVGRVTFAQNGTEWVAEVSEQLDYWV
                     TAGDTPAEISAAYARVTGTPPMMPDYAMGFWQCKLRYRNQQELLEVARGYKQRNLPIS
                     VIVIDFFHWPNQGDWMFDLRDWPDPDAMIAELKEMGIELMVSFWPTVDNRTESYREMK
                     ENGWLVHTERGLPINMDFLGNTTFFDATHPGAREYVWNKAKRNYYDKGVKLFWLDEAE
                     PEFGVYDYDNYRYYAGPVLEVGNIYPRMYAKTFFDGMTAAGEKQVINLLRCAWAGSQK
                     YGALVWSGDIHSSFRSLRNQFAAGLNMGIAGIPWWTTDIGGFHGGNIHDPKFHELLIR
                     WFQWGVFSPVMRLHGNRDPQVLPEQPYRDGIAQCPTGAPNEVWSYGEETGEILTSCLQ
                     LREKLKSYISKIMAETHEKNSPIMRTMFFEFPDQAESWNIYDQYCFGPDLLVAPVMHE
                     GTRSRDVWLPAGETWIDFYTHEHYAGGQTLHHCAPLHQIPVFIREKGKYRQIFPV"
     gene            complement(5916..7289)
                     /locus_tag="LSX49_001200"
     CDS             complement(5916..7289)
                     /locus_tag="LSX49_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7167636.1"
                     /translation="MSSVLETDKSSASDSLPLIQRISYGSLDVAGNLLYCFGSTYILY
                     FYTDVAGISLAVAGIILLLARIVDGIDAPVWGIIIDKTHSRYGKCRPWFLWLPLPFAV
                     FSALSFWSPDISMTGKTIYSAISYMLASILFTGLNTPLSAILPLMTLSPKERLVLNSY
                     RMTGGQIGVLLMNATALPLVAFLGNGNDKAGFIYTAIVFSVISCALTLFAFKNIRELD
                     TDKIQQEPRLPMKKSFSAMKGNWPWILMVLANLIFWIALQQRNTTIVYYLTYNLDRKD
                     LVPLINSLATIQILFIIAIPFFSRYLSKTWIWITGLLVAMFGGGLMWLAGDNIPLMIA
                     AWMLANIGSGIACSMPFAMLGFAVDFGRWKTGIKATGILIAFGSTFCIKMGSGIGTAF
                     AAWIMNSFGYIPNQPQTAAGLDGISWAFIWVPAVLFALAAIPLLFFRKYEAMEECIQH
                     DLQVHNP"
     gene            complement(7678..7941)
                     /gene="rpsT"
                     /locus_tag="LSX49_001201"
     CDS             complement(7678..7941)
                     /gene="rpsT"
                     /locus_tag="LSX49_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBL7167637.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     gene            8044..8262
                     /locus_tag="LSX49_001202"
     CDS             8044..8262
                     /locus_tag="LSX49_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 family protein"
                     /protein_id="HBL7167638.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSARKIAVGGQFLPMICAIAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            8270..9211
                     /gene="ribF"
                     /locus_tag="LSX49_001203"
     CDS             8270..9211
                     /gene="ribF"
                     /locus_tag="LSX49_001203"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBL7167639.1"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            9254..12070
                     /gene="ileS"
                     /locus_tag="LSX49_001204"
     CDS             9254..12070
                     /gene="ileS"
                     /locus_tag="LSX49_001204"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBL7167640.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKTKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVSDYTILGTVKGAELELLRFTHPFMDFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVIALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     gene            12070..12564
                     /gene="lspA"
                     /locus_tag="LSX49_001205"
     CDS             12070..12564
                     /gene="lspA"
                     /locus_tag="LSX49_001205"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBL7167641.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILVVMMYRSKAAQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            12672..13121
                     /gene="fkpB"
                     /locus_tag="LSX49_001206"
     CDS             12672..13121
                     /gene="fkpB"
                     /locus_tag="LSX49_001206"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL7167642.1"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            13123..14073
                     /gene="ispH"
                     /locus_tag="LSX49_001207"
                     /gene_synonym="lytB"
     CDS             13123..14073
                     /gene="ispH"
                     /locus_tag="LSX49_001207"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBL7167643.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     gene            14139..15053
                     /gene="rihC"
                     /locus_tag="LSX49_001208"
     CDS             14139..15053
                     /gene="rihC"
                     /locus_tag="LSX49_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HBL7167644.1"
                     /translation="MHLPIFLDTDPGIDDAVAIAAAIFTPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYNFVEHNRQPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVQVALDLDVKGFQQWVAEVLALAL"
     gene            15076..15441
                     /locus_tag="LSX49_001209"
     CDS             15076..15441
                     /locus_tag="LSX49_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HBL7167645.1"
                     /translation="MTYGEAYLEGWKNIFNYEGVSNRFEFWSFMIGSGVICLLPLLCW
                     WLAVTINNDYGVFIFFALPASFILTLIFAVPAIALAVRRMHDIGYSGWWVTIVVLIPV
                     TGVILLILCCLPSKSQDQA"
     gene            15602..16423
                     /gene="dapB"
                     /locus_tag="LSX49_001210"
     CDS             15602..16423
                     /gene="dapB"
                     /locus_tag="LSX49_001210"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBL7167646.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL"
     gene            16879..18027
                     /gene="carA"
                     /locus_tag="LSX49_001211"
     CDS             16879..18027
                     /gene="carA"
                     /locus_tag="LSX49_001211"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBL7167647.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEPYSWTQGSWTLTGGLPEAKKEDELPYHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIALIEQYRKTAK"
     gene            18045..21266
                     /gene="carB"
                     /locus_tag="LSX49_001212"
     CDS             18045..21266
                     /gene="carB"
                     /locus_tag="LSX49_001212"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBL7167648.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHSMEEALAVAA
                     EVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     ERLKLKQPANATVTTIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            21527..21922
                     /gene="caiF"
                     /locus_tag="LSX49_001213"
     CDS             21527..21922
                     /gene="caiF"
                     /locus_tag="LSX49_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HBL7167649.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(22041..22631)
                     /gene="caiE"
                     /locus_tag="LSX49_001214"
     CDS             complement(22041..22631)
                     /gene="caiE"
                     /locus_tag="LSX49_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HBL7167650.1"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVLAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(22637..23422)
                     /gene="caiD"
                     /locus_tag="LSX49_001215"
     CDS             complement(22637..23422)
                     /gene="caiD"
                     /locus_tag="LSX49_001215"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HBL7167651.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGVVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     gene            complement(23531..25084)
                     /gene="caiC"
                     /locus_tag="LSX49_001216"
     CDS             complement(23531..25084)
                     /gene="caiC"
                     /locus_tag="LSX49_001216"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HBL7167652.1"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSSGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREEST
                     WILQNSQACLLVTSAQFYPMYQQIQQEDASQLRHICLTDMALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDIYL
                     TVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSVRAFWGQVQKYRATVTECIPMMIRTL
                     MVQPPSVNDRQHCLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAK
                     VLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIV
                     VVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCS
                     GKIIRKNLK"
     gene            complement(25157..26374)
                     /gene="caiB"
                     /locus_tag="LSX49_001217"
     CDS             complement(25157..26374)
                     /gene="caiB"
                     /locus_tag="LSX49_001217"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HBL7167653.1"
                     /translation="MDHLTMPKFGPLSGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIAECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            complement(26503..27645)
                     /gene="caiA"
                     /locus_tag="LSX49_001218"
     CDS             complement(26503..27645)
                     /gene="caiA"
                     /locus_tag="LSX49_001218"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HBL7167654.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            complement(27676..29190)
                     /gene="caiT"
                     /locus_tag="LSX49_001219"
     CDS             complement(27676..29190)
                     /gene="caiT"
                     /locus_tag="LSX49_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HBL7167655.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKY"
     gene            29663..30433
                     /locus_tag="LSX49_001220"
     CDS             29663..30433
                     /locus_tag="LSX49_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HBL7167656.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     VLAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     gene            30448..31389
                     /locus_tag="LSX49_001221"
     CDS             30448..31389
                     /locus_tag="LSX49_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBL7167657.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQA
                     IQLGANHVWKLSGKPDERMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LNAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            31440..32726
                     /locus_tag="LSX49_001222"
     CDS             31440..32726
                     /locus_tag="LSX49_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL7167658.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFNGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            32723..33010
                     /gene="fixX"
                     /locus_tag="LSX49_001223"
     CDS             32723..33010
                     /gene="fixX"
                     /locus_tag="LSX49_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HBL7167659.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKRDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     gene            33069..34400
                     /locus_tag="LSX49_001224"
     CDS             33069..34400
                     /locus_tag="LSX49_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7167660.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFEEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWTLPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     gene            34508..35038
                     /gene="kefF"
                     /locus_tag="LSX49_001225"
     CDS             34508..35038
                     /gene="kefF"
                     /locus_tag="LSX49_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HBL7167661.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            35031..36893
                     /gene="kefC"
                     /locus_tag="LSX49_001226"
     CDS             35031..36893
                     /gene="kefC"
                     /locus_tag="LSX49_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HBL7167662.1"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRRAFAVLLFQDIAAI
                     PLVAMIPLLAASSASTTMGAFVLSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            37085..37564
                     /gene="folA"
                     /locus_tag="LSX49_001227"
     CDS             37085..37564
                     /gene="folA"
                     /locus_tag="LSX49_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HBL7167663.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            37650..37883
                     /locus_tag="LSX49_001228"
     CDS             37650..37883
                     /locus_tag="LSX49_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="HBL7167664.1"
                     /translation="MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKH
                     AATRWREENAEAIAALNQLADETGCFSDEYRSF"
     gene            37886..38170
                     /locus_tag="LSX49_001229"
     CDS             37886..38170
                     /locus_tag="LSX49_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="HBL7167665.1"
                     /translation="MQFTVYRSRGRNAAFPFVIDVTSDIIGEINRRIVIPLTPIERFS
                     RIRPPERLNPILLLIDGKEYVLMTHETATVPVNALGTKFCDASAHRTLIK"
     gene            complement(38197..39045)
                     /gene="apaH"
                     /locus_tag="LSX49_001230"
     CDS             complement(38197..39045)
                     /gene="apaH"
                     /locus_tag="LSX49_001230"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HBL7167666.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYNIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLSE
                     GEAVAS"
     gene            complement(39052..39429)
                     /gene="apaG"
                     /locus_tag="LSX49_001231"
     CDS             complement(39052..39429)
                     /gene="apaG"
                     /locus_tag="LSX49_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HBL7167667.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            complement(39432..40253)
                     /gene="rsmA"
                     /locus_tag="LSX49_001232"
     CDS             complement(39432..40253)
                     /gene="rsmA"
                     /locus_tag="LSX49_001232"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBL7167668.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAA
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVGVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            complement(40250..41239)
                     /gene="pdxA"
                     /locus_tag="LSX49_001233"
     CDS             complement(40250..41239)
                     /gene="pdxA"
                     /locus_tag="LSX49_001233"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HBL7167669.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLIVQLAQREWPVELVVCADATLLT
                     DRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRESVTVGLLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLDELREQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     gene            complement(41239..42525)
                     /gene="surA"
                     /locus_tag="LSX49_001234"
     CDS             complement(41239..42525)
                     /gene="surA"
                     /locus_tag="LSX49_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HBL7167670.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            complement(42578..44932)
                     /gene="lptD"
                     /locus_tag="LSX49_001235"
     CDS             complement(42578..44932)
                     /gene="lptD"
                     /locus_tag="LSX49_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HBL7167671.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTRLAESANRVMPQFKVDGRMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSKIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISDRWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            45187..46002
                     /gene="djlA"
                     /locus_tag="LSX49_001236"
     CDS             45187..46002
                     /gene="djlA"
                     /locus_tag="LSX49_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HBL7167672.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQSGSGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            complement(46152..46811)
                     /gene="rluA"
                     /locus_tag="LSX49_001237"
     CDS             complement(46152..46811)
                     /gene="rluA"
                     /locus_tag="LSX49_001237"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HBL7167673.1"
                     /translation="MGMENYNPPQEPWLVVLYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     gene            complement(46823..49729)
                     /gene="rapA"
                     /locus_tag="LSX49_001238"
     CDS             complement(46823..49729)
                     /gene="rapA"
                     /locus_tag="LSX49_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HBL7167674.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDETEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            complement(49894..52245)
                     /gene="polB"
                     /locus_tag="LSX49_001239"
     CDS             complement(49894..52245)
                     /gene="polB"
                     /locus_tag="LSX49_001239"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HBL7167675.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVFLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMRNGAIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPLLLEKLNAWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQVKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKTLIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENHKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            complement(52320..53015)
                     /gene="araD"
                     /locus_tag="LSX49_001240"
     CDS             complement(52320..53015)
                     /gene="araD"
                     /locus_tag="LSX49_001240"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL7167676.1"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRGRGVFVIKPS
                     GVDYSIMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGPIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            complement(53130..54632)
                     /gene="araA"
                     /locus_tag="LSX49_001241"
     CDS             complement(53130..54632)
                     /gene="araA"
                     /locus_tag="LSX49_001241"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBL7167677.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     gene            complement(54643..56343)
                     /gene="araB"
                     /locus_tag="LSX49_001242"
     CDS             complement(54643..56343)
                     /gene="araB"
                     /locus_tag="LSX49_001242"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HBL7167678.1"
                     /translation="MAIAIGLDFGSDSVRALAVECATGEEIATSVEWYPRWQNGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELCVEQRAAVVGIGVDTTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHTPGNVDYSRNIGGIYSSEWFWAKI
                     LHVTRQDNAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQINASQKQLLPALTEVWAQNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
                     "
     gene            56682..57527
                     /gene="araC"
                     /locus_tag="LSX49_001243"
     CDS             56682..57527
                     /gene="araC"
                     /locus_tag="LSX49_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HBL7167679.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGIVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAHEWYHQWVYFRPRA
                     YWHEWVNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCE"
BASE COUNT        13394 a        14651 c        15427 g        14059 t
ORIGIN      
        1 cagaggtgat aaaccagaag cggtgacctg gggctaacct gataatcata ataaatgtaa
       61 tgtatgccat ttagggctat gcccgcctga ttcagtgcta cgcattgaat caggttcttt
      121 tcgcgttgaa caatatcaag atacggctat tcgcagggag tggatatgtt taccaacgta
      181 aatgttgatt gttgcaaaac accaggatgt aaaaacctgg ggttgctgaa tagccaggat
      241 tatgtcgcac agggtaaaaa tattttatgc cgtgaatgtg gttacttgtt tccagtgata
      301 tctgaacagt cgcttaatat ttatcgtaat attgtgaatc actcctggag aggtttgatt
      361 tgccaatgtt caacttgcgg aggcacgtcc ctcaaaaaat atggatattc tgcacaaggc
      421 cagagaagaa tgtattgcca tcattgtgag aaaacattta tcactctgga acatgtaatt
      481 accacaccac gaggagccca gttagcattg atgattgagc aaggggaggc acttgcggat
      541 atcagaaagt cattacttct taacagcact ggacttagcc gtgaactgtt aaaattagcg
      601 cgtgaagcaa actataaaga aagtcgacag tgtttcccag cttctgatat taccctgagt
      661 acccgcgctt ttcgcgtcaa gtataatggt agcaataact ctctttatgc tcttgttacc
      721 gcagaagaac aaagcggcag ggtggttgcc atctcaacca attactcccc atctgccgta
      781 gagcaacatt atcaatacac atcgaactat gaagagcgta tgtctccagg gacgctggca
      841 catcatgtcc agcgcaaaga gttacttact atgcggcggg ataccttgtt tgatattgat
      901 tacggcccgg cagttttaca tcaaaacgat ccgggaatgt tggtaaaacc ggttcttccg
      961 gcatatcgtc attttgaact ggtcagaata ctgaccgatg agcattccaa caacgttcag
     1021 cattaccttg atcacgaatg ctttatattg ggcggctgcc tgatggctaa tttgcagcat
     1081 attcatcaag gtcgctgcca tatttccttt gtcaaagagc gcggtgtggc acccgccacc
     1141 attgattttc cgccgcgatt attccttagt ggtggggtac gaaataatgt ctggcgtgca
     1201 ttttctaacc gcaattattc aatggctgta tgcaatctca ctggcagtaa gaaagtccgc
     1261 gagatgcggc atgcaacatt gaacagtgcg acgcgtttta tccactttgt ggagaaccat
     1321 cctttcctta tatcattgaa ccgaatgtct cctgcgaatg tcgtttctac attagatatc
     1381 ctcaaacatc tgtggaataa aaaactagag catggaacaa tttaattatt acttttccga
     1441 ataatttctt cagaaatctt gacattagac tatgattaat ggggtttaag gtcatcagcc
     1501 gccgctttcg ggcatcaaaa actcatctct cgctgatggc gcaattcttt taatagatcg
     1561 taaaaagcga gctattccta cactataatc tgattttaac gatgattcgt gcggggtaaa
     1621 atcgtgaaaa cgatctattc acctgaagag aaataaaaag tgaaacatct gcatcgattc
     1681 tttagcagtg atgcctcggg aggcattatt ctcattattg ccgctgtatt agcgatgatt
     1741 atggccaaca gcggtgcaac cagtggatgg tatcacgact ttcttgagac gccggttcag
     1801 ctccgggttg ggacacttga gatcaacaag aacatgctgc tatggatcaa tgacgctctg
     1861 atggcggtat ttttcctgtt ggttggtctg gaagttaaac gcgagctgat gcaaggttcg
     1921 ctggccagtc tgcgccaggc ggcatttcct gttattgccg caatcggcgg gatgattgtc
     1981 ccggcattgc tctatctggc ttttaactat gccgatccta tcactcgcga aggctgggca
     2041 atcccggcgg cgactgacat tgcctttgca cttggtgtgt tggcgctgtt gggaagtcgt
     2101 gttccgttag cgctgaagat ctttttgatg gctctggcta ttatcgacga tcttggggcc
     2161 atcattatca tcgcattgtt ctacactaat gacttatcga tggcctctct tggcgtcgcg
     2221 gctgtagcaa ttgcggtact cgcggtattg aatctgtgtg gtgtacgccg cacgggcgtt
     2281 tatattctgg ttggcgtggt gctgtggaca gcggtgttga aatcaggtgt ccatgcaacg
     2341 ctggctggcg tcattgtcgg cttctttatt ccgttaaaag agaagcatgg gcgctctccg
     2401 gctaaacgtc tggagcatgt tttgcatcca tgggtggcgt atctgatttt gccgctgttt
     2461 gcatttgcta atgctggcgt ttcactgcaa ggtgtcacgc tggaaggttt gacctccatt
     2521 ctgccattag ggatcatcgc tggtttgctg attggcaagc cactgggtat tagtctgttc
     2581 tgctggttgg cgctgcgttt gaaactggca catctgccag agggaacgac ttaccagcaa
     2641 attatggcgg ttggtatcct gtgcggtatc ggttttacta tgtctatctt tattgccagc
     2701 ctggcatttg gtagcgtaga tccagaactg attaactggg caaaattagg tatccttgtc
     2761 ggttcaattt cttcggcggt aattggatat agctggttac gcgttcgttt acgtccatca
     2821 gtttgacagg acgatgtact ggggagccat aaacggctcc cttttcattg ttatcaggga
     2881 gagaaatgag catgtctcat atcaattaca accacttgta ttacttctgg catgtctaca
     2941 aagaaggttc tgtggttggc gcagcggagg cgctttattt aacaccacaa accattaccg
     3001 ggcagatccg ggcgctggaa gagcgcctgc aagggaaact atttaagcgt aaaggacgtg
     3061 gtctggaacc cagcgaactg ggggaactgg tctatcgcta tgccgataaa atgttcacct
     3121 taagccagga aatgctggat atcgtcaact atcgcaaaga gtccaactta ttgtttgatg
     3181 ttggtgtggc agatgcactt tccaaacgtc tggtcagtag cgtacttaac gccgcagtgg
     3241 tagaaggcga gccgattcat cttcgctgct tcgaatccac ccacgaaatg ctgctggagc
     3301 aattaagtca gcataaactg gatatgatca tttccgactg tccgatagat tctacgcagc
     3361 aggaaggcct gttctccgtg agaattggcg aatgtggcgt gagtttctgg tgtacaaatc
     3421 caccaccgga aaaaccgttc ccggcttgtc tggaagaacg gcggcttttg attcctgggc
     3481 gacgttcaat gttagggcgc aaattgctta actggtttaa ctcccaggga ttaaacgtag
     3541 aaatccttgg cgagtttgat gatgccgcgt tgatgaaagc ttttggtgcg atgcacaatg
     3601 caatcttcgt tgctccaacg ctttatgcat atgactttta tgccgataaa actgtcgtag
     3661 aaattggtcg cgtcgagaat gtgatggaag agtaccatgc tatttttgct gagcggatga
     3721 ttcagcaccc ggcggtacag cgaatctgca atacggatta ttcttcgttg ttttctcccg
     3781 cctcacgata gctattaaaa ctcacgcccc gctacatacg gggcgtgcta atgaacaaac
     3841 gatgtccttt aaacgggaaa tatctggcga tatttccctt tctcgcgaat gaataccggt
     3901 atctggtgca gcggtgcgca atgatgaagc gtttgcccac ccgcgtagtg ttcatgggta
     3961 taaaaatcga tccatgtctc tccagcaggc aaccagacat cacgtgaacg tgtaccttcg
     4021 tgcattacag gggcaacgag aaggtctggg ccaaagcagt actgatcata aatattccag
     4081 ctttctgcct ggtcaggaaa ttcaaagaac atcgtgcgca ttatcgggct gttcttctcg
     4141 tgcgtctcag ccataatttt actgatataa gatttcagtt tttcacgcaa ctgcaggcag
     4201 gaagtgagaa tttcaccggt ttcttcacca tagctccaga cttcattcgg cgcgccagtc
     4261 ggacattgtg ctatgccatc acgatagggt tgttcaggca aaacctgcgg gtcgcggttg
     4321 ccatgtaaac gcattactgg gctgaatacc ccccactgga accagcgaat taacagttca
     4381 tggaatttcg gatcgtgaat attaccgccg tggaaaccac caatatcggt tgtccaccac
     4441 gggatcccgg caattcccat gttcaagcca gcggcaaact gattacgcaa agaacggaaa
     4501 gaggagtgaa tatcgcctga ccacaccaga gcgccatatt tctgactgcc agcccaggca
     4561 cagcgcagca ggttaatcac ctgcttttca ccagccgcgg tcataccatc gaagaacgtt
     4621 ttggcgtaca tacgcggata gatattaccg acttccagca caggccctgc gtagtaacga
     4681 tagttgtcat aatcgtaaac accgaactct ggctcggctt catccagcca gaacagtttc
     4741 acgcctttat cgtaataatt gcgtttggct ttgttccaga catattcccg tgcgccagga
     4801 tgggtagcat caaagaacgt ggtgttgcca aggaaatcca tattgatagg caaaccacgc
     4861 tcggtgtgga ccagccagcc gttttctttc atctcccgat aactctcggt acggttatca
     4921 accgtgggcc agaaggagac catcagttca atgcccatct cttttagttc ggcaatcatg
     4981 gcatcgggat cgggccagtc gcgcagatcg aacatccagt caccctgatt cggccaatgg
     5041 aagaaatcga tgacaatcac cgaaataggc aaattacgct gcttgtagcc acgtgcaact
     5101 tctagtaact cttgctgatt acggtagcgc aacttgcact gccagaatcc catggcgtaa
     5161 tcgggcatca ttggcggcgt accggtaaca cgtgcatagg cggcgctgat ttctgcggga
     5221 gtatcccctg cggtaaccca gtagtccaac tgttcgctaa cttctgccac ccattccgtg
     5281 ccattttgcg cgaaagtgac gcgacccacc gctgggttat tccacagaaa accatagccg
     5341 cgattagaaa gcaggaaggg aaccgatgcc tgagaattac gctgcgccag ctctagcata
     5401 cagcctttta aatccagatt tggctgctgg tactgcccca tgccaaacaa cttttcgcca
     5461 tcgttggctt cgaaccgcgc cttgattgtg tatttcccgc cgggaatcgg tttgaactcg
     5521 cgggcctgta aattcagggc gctgacatac tgaccgtggg ccgactcatc ttcgccaatt
     5581 tcgccgcgct gacgccagaa ctcctgcagc aggcattttt ctgcattacg ccagaaagag
     5641 atctgaccct gcagattaac aatggcggtg attttgccgt tttgtagtgt tgcctgcttt
     5701 tcttcatatg tgatataggc gacagcatca cctttttctt ctgttaatgc ccagttttca
     5761 ttgcgcatca tcggcagatg gcgaccgcta cgcacacgta aactgttctc accccatgct
     5821 tcaatccaga gataacgatc gtcttgttgc cagaccagac gatggggatc ttgcttaata
     5881 aacgacataa tttcctccag gagcttgtga catgtttaag ggttatgaac ttgcaaatcg
     5941 tgttggatgc actcttccat cgcttcatat ttacgaaaga agagcagtgg aatggcggcg
     6001 agtgcaaaga gcacggctgg cacccagata aacgcccagc taataccgtc cagaccggcg
     6061 gcagtttgtg gctggttggg aatatagcca aagctgttca taatccaggc ggcgaaggcg
     6121 gtgccgatac cactgcccat cttgatgcag aaggtactgc cgaaggcgat tagaatgccg
     6181 gtagctttaa tccctgtttt ccagcgacca aaatcaaccg cgaaaccaag catggcgaag
     6241 ggcatagagc aggcaatgcc actgccaata ttcgccagca tccaggcggc aatcatcaaa
     6301 ggaatattgt ctccagccag ccacatcagt cctccgccga acatggcgac cagcaggccg
     6361 gtgatccaaa tccaggtttt ggagaggtaa cggctgaaaa acggaattgc gatgataaac
     6421 aaaatctgaa tggtggcgag gctgttgatc aagggaacta aatctttgcg atccaggttg
     6481 taggttaaat agtaaacaat ggttgtgttg cgctgctgta aggcaatcca gaagatgaga
     6541 tttgccagca ccatcaggat ccacggccag ttgcctttca ttgccgaaaa gctctttttc
     6601 atcggcagac gtggttcctg ctgtattttg tcggtatcca gttctcgaat atttttgaag
     6661 gcaaatagcg ttagcgcaca ggagattacg gaaaagacga tagcagtata aataaatcct
     6721 gccttatcat taccgtttcc aagaaaagcc actaacggta gcgccgtcgc attcattaat
     6781 aacacgccaa tttgcccgcc ggtcatccgg taagagttta ataccaaccg ttcttttggt
     6841 gataacgtca tcaaaggtaa tattgcgctt agcggcgtgt ttaaaccggt aaaaagaatg
     6901 ctggctaaca tgtacgatat tgctgaatat atggttttac ctgtcatact gatatctggc
     6961 gaccagaatg agagtgcgct aaatacagca aaaggtaatg gcaaccataa aaaccacggc
     7021 cgacatttac cgtagcggga atgcgtttta tcaataataa tcccccatac cggggcatcg
     7081 ataccgtcta caatacgcgc cagtagcagg atgatgccag ctacggcaag gcttatgccc
     7141 gccacgtcag tgtagaaata gagaatgtag gtggagccaa aacagtagag cagattacct
     7201 gcaacatcca gcgaaccata gctgatccgt tgtattaaag gcagtgaatc ggatgcggat
     7261 gatttatcag tttcaagtac ggaactcatt atattctctc cagaacaaga atgcctggct
     7321 cagaaaaacg acttttactt tctaagcaaa tacatgctaa ctatccttga tgcgtattta
     7381 ttaatgatgt aaagcaacgt tgtggcaatg agagtaatta aagtggggaa gcgcgacaat
     7441 tataattttt cgttttaagg ttgcgttaat tagtttttta ttcagttttc ctgctatttg
     7501 ttatacagtt cacgttttac agccaaatga aatattttat ctttcacaat gaaaaagcat
     7561 caattatatt tatgatgtat tcatggagaa aatatataat cgattaacgg taacttccgc
     7621 aggcataaaa aaacccgcca gagcgggttt ttttacaaag ctgacaacaa caggcaatta
     7681 agccagtttg ttgatctgtg cagtcaggtt agccttatga cgtgcagctt tgtttttgtg
     7741 gatcagacct ttagcagcct gacggtccac gattggttgc atttcgttaa atgctttctg
     7801 tgcagcagct ttgtcgccag cttcgatagc tgcgtatact ttcttgatga aagtacgcat
     7861 catagagcga cggcttgcgt tgtgcttacg agccttttca gactgaatgg cgcgcttctt
     7921 agctgatttg atattagcca aggtccaact cccaaatgtg ttctatatgg acaattcaaa
     7981 ggccgaggaa tatgcccttt tagccttctt ttgtcaatgg atttgtgcaa ataagcgccg
     8041 ttaatgtgcc ggcactcgtt acgtagtgat ggcgcaggat tctaccagct tgcggggtgt
     8101 gaatacagct tttccgcgag aaaaattgca gtaggcggtc agtttcttcc catgatttgc
     8161 gccatagcaa tgaaaagcca cttctttctg atttcggtac tcaatcgccg gttaaccttg
     8221 accgctgtac aaggtatact cggacgattt tcactgtttt gagccagaca tgaagctgat
     8281 acgcggcata cataatctca gccaggcccc gcaagaaggg tgtgtgctga ctattggtaa
     8341 tttcgacggc gtgcatcgcg gtcatcgcgc gctgttacag ggcttgcagg aagaagggcg
     8401 caagcgcaac ttaccggtga tggtgatgct ttttgaacct caaccactgg aactgtttgc
     8461 tactgataaa gccccggcac ggctgacccg gctgcgggaa aaactgcgtt atcttgcaga
     8521 gtgtggcgtt gattacgtgc tgtgcgtgcg ttttgacagg cgttttgcgg cgttaaccgc
     8581 gcaaaacttc atcagtgatc ttctggtgaa gcacttgcgg gtaaaatttc ttgccgtagg
     8641 tgacgatttc cgctttggcg ctggtcgtga aggcgatttc ttgttattac agaaagcggg
     8701 tatggaatac ggcttcgata tcaccagcac gcaaactttt tgcgaaggtg gcgtgcgtat
     8761 cagcagcacc gccgtgcgtc aggcgctggc ggatgacaat ctggctctgg cagaaagttt
     8821 actggggcac ccgtttgcca tctccgggcg tgtagtccac ggtgatgaat tagggcgcac
     8881 tataggtttc ccgacggcga atgtaccgct acgccgtcag gtttccccgg tgaaaggggt
     8941 ttatgcggta gaagtgttgg gccttggcga aaagccgtta cccggcgttg caaacatcgg
     9001 aacacgccca acggttgccg gtattcgcca gcaactggaa gtgcatttgt tagatgttgc
     9061 aatggacctt tatggtcgcc atatacaagt agtgctgcgt aaaaaaatac gcaatgagca
     9121 gcgatttgca tcgctggacg aactgaaagc gcagattgcg cgtgatgaat taaccgcccg
     9181 cgaatttttt gggctaacaa aaccggctta agcctgttat gtaatcaaac cgaaatacgg
     9241 aaccgagaat ctgatgagtg actataaatc aaccctgaat ttgccggaaa cagggttccc
     9301 gatgcgtggc gatctcgcca agcgcgaacc gggaatgctg gcgcgttgga ctgatgatga
     9361 tctgtacggc atcattcgtg cagctaaaaa aggcaaaaaa accttcattc tgcatgatgg
     9421 ccctccttat gcgaatggca gcattcatat tggtcactcg gttaacaaga ttctgaaaga
     9481 cattatcatt aagtccaaag ggctttctgg atatgactcg ccgtatgtgc ctggctggga
     9541 ctgtcatggt ctgccaatcg aactgaaagt agagcaagaa tacggtaagc cgggggagaa
     9601 attcaccgcc gctgagttcc gcgccaagtg ccgcgaatac gctgcgaccc aggttgacgg
     9661 tcagcgcaaa gactttatcc gtctgggcgt gctgggcgac tggtcgcacc cgtacctgac
     9721 catggacttc aaaactgaag ccaacatcat ccgcgcgctg ggcaaaatca tcggcaacgg
     9781 tcacctgcac aaaggcgcga agccggtgca ctggtgcgtt gactgccgtt ctgcactggc
     9841 agaagcggaa gttgagtatt acgacaaaac ttctccgtcc atcgacgtcg ctttccaggc
     9901 ggtcgatcag gatgcgctga aaacgaaatt tggcgtaagc aatgttaacg gcccaatttc
     9961 gctggttata tggaccacca cgccgtggac gctgcctgct aaccgcgcaa tctccattgc
    10021 acctgatttt gattatgcgc tggtgcaaat cgacggtcag gccgtgattc tggcgaaaga
    10081 tctggttgaa agcgtaatgc agcgtatcgg cgttagcgat tacaccattc ttggcacggt
    10141 gaaaggtgct gagctggaac tgttgcgctt tacccatccg tttatggact tcgatgttcc
    10201 ggcaattctt ggcgaccacg ttacgctgga tgccggtacc ggtgccgttc ataccgcgcc
    10261 aggccacggt ccggacgact atgtgatcgg tcaaaaatat ggtctggaaa ccgctaaccc
    10321 ggttggcccg gacggcactt atctgccggg tacttacccg actctggatg gcgttaacgt
    10381 cttcaaagcg aacgatattg tcattgcgtt gttgcaggaa aaaggcgcac tgttgcacgt
    10441 tgagaaaatg caacacagct atccgtgctg ctggcgtcat aaaacgccga tcatcttccg
    10501 cgcgacgccg cagtggttcg tcagcatgga tcagaaaggt ctgcgtgcgc agtcactgaa
    10561 agagatcaaa ggcgtgcagt ggatccctga ctggggccag gcgcgtatcg agtcgatggt
    10621 tgctaaccgt cctgactggt gtatctctcg tcagcgtacc tggggcgtgc cgatgtcact
    10681 gttcgtgcac aaagacacag aagaactgca tccgcgtact ctcgaactga tggaagaagt
    10741 ggcaaaacgc gttgaagttg acggcatcca ggcgtggtgg gatctcgatg cgaaagagat
    10801 cctcggcgac gaagctgacc agtatgtgaa agtaccggat acgctggatg tatggtttga
    10861 ctccggatct acccactctt ccgttgttga tgtgcgtccg gaatttgccg gtcacgcagc
    10921 ggacatgtat ctggaaggtt ctgaccaaca ccgtggctgg ttcatgtctt ccctgatgat
    10981 ctctaccgcg atgaagggca aagcgccata tcgtcaggta ctgactcacg gctttaccgt
    11041 ggatggtcag ggtcgcaaga tgtctaaatc catcggtaac accgtttcgc cgcaggatgt
    11101 gatgaacaaa ctgggtgcgg atattctgcg tctgtgggtg gcatcaaccg actacaccgg
    11161 cgaaatggct gtttctgacg agattctgaa acgtgctgcc gacagctatc gtcgtatccg
    11221 taacaccgcg cgcttcctgc tggcaaacct gaacggtttt gatccggcaa aagatatggt
    11281 gaaaccggaa gagatggtgg tactggatcg ctgggccgta ggttgtgcga aagcggcaca
    11341 ggaagacatc ctcaaggcgt acgaagcata cgatttccac gaagtggtac agcgtctgat
    11401 gcgcttctgc tccgttgaga tgggttcctt ctacctcgac atcatcaaag accgtcagta
    11461 taccgccaaa gcggacagcg tggcgcgtcg tagctgccag actgcgctgt atcacatcgc
    11521 agaagcgctg gttcgctgga tggcaccaat cctctccttc accgctgatg aagtgtgggg
    11581 ctacctgccg ggcgaacgtg aaaaatacgt cttcaccggc gagtggtacg aaggcctgtt
    11641 tggtctggca gacagtgaag caatgaacga tgcgttctgg gacgagctgt tgaaagtgcg
    11701 tggcgaagtg aacaaagtca ttgagcaagc gcgtgccgat aagaaagtgg gcggctcgct
    11761 ggaagctgca gtaaccttgt atgcagaacc ggaactggcg gcgaaactga ccgcgctggg
    11821 cgatgaatta cgatttgtcc tgttgacctc cggcgctacc gttgcagact ataacgacgc
    11881 acctgctgat gcccagcaga gcgaagtcct caaagggctg aaagtcgcgt tgagtaaagc
    11941 cgaaggtgag aagtgccctc gctgctggca ctacacccag gatgtcggca aggtggcgga
    12001 acacgcagaa atctgcggcc gctgtgtcag caacgtcgcc ggtgacggtg aaaaacgtaa
    12061 gtttgcctga tgagtcaatc gatctgttca acagggctac gctggctgtg gctggtggta
    12121 gtcgtgctga ttatcgatct gggcagcaaa tacctgatcc tccagaactt tgctctgggg
    12181 gatacggtcc cgctgttccc gtcgcttaat ctgcattatg cgcgtaacta tggcgcggcg
    12241 tttagtttcc ttgccgatag cggcggctgg cagcgttggt tctttgccgg tattgcgatt
    12301 ggtattagcg tgatcctggt agtgatgatg tatcgctcga aggccgcgca gaagctaaac
    12361 aatatcgctt acgcgctgat tattggcggc gcgctgggca acctgttcga ccgcctgtgg
    12421 cacggcttcg ttgtcgatat gatcgacttc tacgtcggcg actggcactt cgccaccttc
    12481 aaccttgccg atactgccat ttgtgtcggt gcggcactga ttgtgctgga aggtttttta
    12541 ccttctaaag cgaaaaaaca ataataaacc ctgccggatg cgatgctgac gcatcttatc
    12601 cggcctacag attgctgcga aatcgtaggc cgcatccggc aaaaatcctc aaaatataag
    12661 agcaaacctg catgtctgaa tctgtacaga gcaatagcgc cgtcctggtg cacttcacgc
    12721 tgaaactcga tgatggcacc accgctgagt ctacccgcaa caacggtaaa ccggcgctgt
    12781 tccgcctggg tgatgcttct ctttctgaag ggctggagca acacctgctg gggctgaaag
    12841 tgggcgataa aaccaccttc tcgctggagc cagatgcggc gtttggcgtg ccgtcaccgg
    12901 acctgattca gtacttctcc cgccgtgaat ttatggatgc aggcgagcca gaaattggcg
    12961 caatcatgct ttttaccgca atggatggca gtgagatgcc tggcgtgatc cgcgaaatta
    13021 acggcgactc cattaccgtt gatttcaacc atccgctggc cgggcagacc gttcattttg
    13081 atattgaagt gctggaaatc gatccggcac tggaggcgta acatgcagat cctgttggcc
    13141 aacccgcgtg gtttttgtgc cggggtagac cgcgctatca gcattgttga aaacgcgctg
    13201 gccatttacg gcgcaccgat atatgtccgt cacgaagtgg tgcataaccg ctacgtggtc
    13261 gatagcctgc gcgagcgtgg ggctatcttt attgagcaga ttagcgaagt accggacggc
    13321 gcgatcctga ttttctccgc acacggtgtt tctcaggcag tacgtaacga agcgaaaagc
    13381 cgcgatttga cggtgtttga tgccacctgt ccgctggtga ccaaagtgca tatggaagtc
    13441 gcccgcgcca gccgtcgtgg tgaagaatct attctcatcg gtcacgccgg gcacccggaa
    13501 gtggaaggga cgatgggcca gtacagcaac ccggaagggg gaatgtatct ggtcgaatcg
    13561 ccagacgatg tgtggaaact gacggtcaaa aatgaagaga agctctcctt tatgacccaa
    13621 accacgctgt cggtggatga cacgtctgat gtgatcgacg cgctgcgtaa acgcttcccg
    13681 aaaattgtcg gtccgcgcaa agatgacatc tgctacgcca cgactaaccg tcaggaagcg
    13741 gtacgcgccc tggcagagca ggcggaagta gtactggtgg ttggttcgaa aaactcctcc
    13801 aactccaacc gtctggcgga actggcccag cgtatgggca aacgcgcatt tttgattgac
    13861 gatgcgaaag atatccagga agagtgggtg aaagaggtta aatgcgtcgg cgtgactgcg
    13921 ggcgcatcgg ctccggatat tctggtgcag aatgtggtgg cacgcttgca gcagcttggc
    13981 ggtggcgaag ccattccgct ggaaggccgc gaagaaaata tcgtcttcga agtgccgaaa
    14041 gagctgcgtg tcgatattcg tgaagtcgat taagtcatta gtagtctaag ttatgcgaaa
    14101 atgccggtct tgttaccggc attttttatg gagaaaacat gcatttacct atcttcctcg
    14161 atacagaccc cggcattgac gatgccgttg ccattgccgc cgcgattttt acccccgaac
    14221 tcgatctgca actgatgacc acagtcgcgg gtaatgtttc ggtagagaaa accacccgca
    14281 acgccctgca actgctgcat ttctggaatg tggatattcc gcttgcccag ggcgctgccg
    14341 taccactggt tcgtgcgccg cgcgatgcgg catctgtaca cggtgaatcg ggaatggctg
    14401 gctataactt tgttgaacac aaccgtcagc cactgggtat accggcgttt ctggcaattc
    14461 gtgatgccct gatgcgtgcg ccagagcccg ttaccctggt ggctatcggt ccgttaacca
    14521 atattgcgct gttactttca caatgcccgg aatgtaagcc gtatattcgc cgtctggtga
    14581 tcatgggcgg ttctgctggt cgcggcaact gcacaccaaa cgccgagttt aatatcgctg
    14641 ccgatccaga agcggcagcc tgtgtcttcc gtagcggcat cgaaatcgtc atgtgcggtc
    14701 tggatgtcac caatcaggca atattaaccc ctgactatct cgctactttg ccggagttga
    14761 atcgcaccgg aaaaatgcta cacgccctgt ttagccacta ccgtagcggc agtatgcaaa
    14821 gtggactacg tatgcacgat ctttgcgcta tcgcctggct ggtgcgcccg gaattgttca
    14881 cactcaaacc gtgttttgtc gcggtagaaa ctcagggtga atttacctca ggcacgacgg
    14941 ttgttgatat cgacggttgc ctgggcaaac cagccaatgt acaggtggcg ctggatctgg
    15001 atgtgaaagg cttccagcag tgggtggctg aggtgctggc cctggcgctc taataataaa
    15061 acaaggaagt gttctatgac gtatggagaa gcgtatctgg aagggtggaa aaacatcttt
    15121 aattatgaag gtgtttccaa tcgcttcgag ttctggtcgt ttatgattgg tagtggcgtt
    15181 atctgtctgc ttccgctttt atgttggtgg ttagcggtaa caattaacaa tgactatggt
    15241 gttttcattt tttttgcgct gcccgcgtca tttattttaa cgttgatttt tgccgtaccg
    15301 gcgatagcgt tagccgtcag aaggatgcac gatatcggat attcagggtg gtgggttacc
    15361 attgtcgtgt tgatccctgt tacgggcgta attctgctta tactgtgctg cctgccgtca
    15421 aagtcacaag accaggcata atgccagagg gtatgacgca tcactttctg cgtcatgcct
    15481 ttcactgata tccctccctg tttatcatta atttctaatt atcagcgttt ttggctggcg
    15541 gcgtagcgat gcgctggtta ctctgaaaac ggtctatgca aattaacaaa agagaatagc
    15601 tatgcatgat gcaaacatcc gcgttgccat cgcgggagcc gggggccgta tgggccgcca
    15661 gttgattcaa gcggcgctgg cattagaagg cgtgcagctg ggcgcggcgc tggagcgcga
    15721 aggatcttct ttactgggca gcgatgcggg cgaactggcc ggagccggga aaacaggcgt
    15781 tactgtgcaa agtagtcttg atgcgataaa agatgatttt gatgtgttta tcgattttac
    15841 ccgtccggaa ggtacgctga accatctcgc tttttgtcgc cagcatggca aagggatggt
    15901 gatcggcact acggggtttg acgaagccgg taaacaggcg attcgtgacg ccgccgccga
    15961 tattgcgatt gtctttgccg ccaattttag cgttggcgtt aacgtcatgc ttaaactgct
    16021 ggagaaagca gccaaagtga tgggggacta caccgatatc gaaattattg aagcacatca
    16081 tagacataaa gttgatgcgc cgtcaggcac cgcactggca atgggagagg cgatcgccca
    16141 cgctcttgat aaagatctga aagattgcgc ggtctacagt cgtgaaggcc ataccggtga
    16201 acgtgtgcct ggcaccattg gttttgccac cgtgcgtgca ggtgacatcg ttggcgaaca
    16261 taccgcgatg tttgccgata ttggcgagcg tctggagatc acccataagg catccagccg
    16321 catgacattt gctaacggtg cggtaagatc ggctttgtgg ttgagtggta aggaaagtgg
    16381 tctttttgat atgcgagatg tgcttgatct caataatctg taaccacaaa atatttataa
    16441 tgatgcaaaa ataacacatt taattcattg aatataaagg gctttaattt ttggcccttt
    16501 tatttttggt gttatgtttt taaatttaat gcaaatgctg aaagttacat gttttgtatt
    16561 ctgtttttgt tgttttaatg taaattttga ccatttggtc cacttttttc tactcatttt
    16621 gatttcatgc aatcttcttg ctgcgcaagc gttttccaga acatgttata tgatcttttt
    16681 gtcgcttaat gcctgtaaaa catgcatgag ccacaaaata atataaaaaa tcccgccatt
    16741 aagttgactt ttagctccca tatctccaga atgccgccgt ttgccagaaa ttcgtcggta
    16801 agcagatttg cattgattta cgtcatcatt gtgaattaat atgcaaataa agtgagtgaa
    16861 tattctctgg agggtgtttt gattaagtca gcgctattgg ttctggaaga cggaacccag
    16921 tttcacggtc gggccatagg ggcaacaggt tcggcggttg gggaagtcgt tttcaatact
    16981 tcaatgaccg gttatcaaga aatcctcact gatccttcct attctcgtca aatcgttact
    17041 cttacttatc cccatattgg caatgtcggc actaatgacg ccgatgaaga atcttctcag
    17101 gtacatgccc aaggtctggt gattcgcgac ctgccgctga ttgccagcaa ctttcgtaat
    17161 accgaagacc tctcttctta cctgaagcgc cataacatcg tggcgattgc cgatatcgat
    17221 acccgtaagc tgacgcgttt actgcgcgag aaaggcgcac agaatggctg cattatcgca
    17281 ggcgataacc cggatgcggc gctggcgtta gaaaaagccc gcgcgttccc tggcctgaat
    17341 ggcatggatc tggcaaaaga agtgactacc gcagaaccct atagctggac acaagggagc
    17401 tggacgctga ccggcggtct gccagaagcg aaaaaagaag acgagctgcc gtaccacgtc
    17461 gtggcttatg attttggtgc caagcgcaac atcctgcgga tgctggtgga tagaggctgt
    17521 cgtctgacca tcgttccggc gcaaacttct gcggaagatg tgctgaaaat gaatccagac
    17581 ggcatcttcc tctccaacgg tcctggcgac ccggccccgt gcgattacgc cattaccgcc
    17641 atccagaaat tcctcgaaac cgatattccg gtattcggca tctgcctcgg ccatcagctg
    17701 ctggcgctgg cgagcggtgc gaagactgtc aaaatgaaat ttggtcacca cggcggcaac
    17761 catccggtta aagatgttga gaaaaatgtg gtgatgatca ccgcccagaa ccacggtttt
    17821 gcggtggatg aagcaacatt acctgcaaac ctgcgtgtca cacataaatc cctgttcgac
    17881 ggtacgttac agggcattca tcgtaccgat aaaccggcgt tcagcttcca gggacacccg
    17941 gaagccagcc ctggtccaca cgacgccgcg ccgttgtttg accactttat cgcgttaatt
    18001 gagcagtacc gtaaaaccgc taagtaatca ggagtaaaag agccatgcca aaacgtacag
    18061 atataaaaag tatcctgatt ctgggtgcgg gcccgattgt tatcggtcag gcgtgtgagt
    18121 ttgactactc tggcgcgcaa gcgtgtaaag ccctgcgtga agagggttac cgcgtcattc
    18181 tggtgaactc caacccggcg accatcatga ccgacccgga aatggctgat gcaacctaca
    18241 tcgagccgat tcactgggaa gtggtacgca agattattga aaaagagcgc ccggacgcgg
    18301 tgctgccaac catggggggg cagacggcgc tgaactgtgc gctggagctt gagcgtcagg
    18361 gcgtgctgga agagttcggc gtcaccatga ttggtgccac tgccgatgcg attgataaag
    18421 ccgaagaccg ccgccgtttc gacgtagcga tgaagaaaat cggtctggaa actgcgcgtt
    18481 ccggtatcgc tcattcaatg gaagaagcgc tggcggttgc cgctgaagtt ggcttcccgt
    18541 gcattattcg cccatccttt accatgggcg gtagcggcgg cggtatcgct tataaccgcg
    18601 aagagtttga agaaatttgc gcccgcggtc tggatctttc tccgactaaa gagctgctga
    18661 ttgatgagtc gctgatcggc tggaaagagt acgagatgga agtggtgcgt gataaaaacg
    18721 acaactgtat catcgtctgc tctatcgaaa actttgatgc gatgggcatc cacaccggtg
    18781 actccatcac tgtcgcgcca gcccaaacgc tgaccgacaa agaatatcaa atcatgcgta
    18841 acgcctcgat ggcggtactg cgtgaaatcg gcgttgaaac cggtggttcc aacgtccagt
    18901 ttgcggtgaa cccgaaaaac ggtcgcctga ttgttatcga aatgaaccca cgcgtgtctc
    18961 gctcctctgc gctggcgtcg aaagccactg gtttcccgat tgccaaagtg gcggcgaaac
    19021 tggcggtggg ttacaccctc gacgagctga tgaacgacat caccggtggg cgtactccgg
    19081 cctccttcga gccgtccatc gactatgtgg ttactaaaat tcctcgcttc aacttcgaga
    19141 aattcgccgg tgctaacgac cgtctgacca ctcagatgaa atcggttggc gaagtgatgg
    19201 cgattggtcg cacgcagcag gaatccctgc aaaaagcgct gcgcggcctg gaagtgggcg
    19261 caactggctt cgatccgaaa gtgagtctcg acgacccgga agcgctgact aaaatccgcc
    19321 gcgaactgaa agatgcaggc gcagagcgta tctggtatat cgctgatgcc ttccgcgcgg
    19381 gcctgtctgt agacggcgtg tttaatttga ccaacattga ccgctggttc ctggtacaga
    19441 ttgaagagct ggtgcgtctg gaagagaaag tcgcagaagt gggcatcact ggcctgaacg
    19501 ctgaattcct gcgccagctg aaacgcaaag gctttgccga tgcgcgtctg gcaaaactcg
    19561 cgggcgtgcg tgaagcagaa atccgcaagc tgcgcgacca gtatgacttg cacccggttt
    19621 ataagcgcgt ggatacctgt gcggcagagt tcgccaccga caccgcttac atgtactcca
    19681 cttatgaaga agagtgcgaa gcgaatccgt ccaccgatcg tgaaaaaatc atggtgctcg
    19741 gcggcggccc gaaccgtatc ggtcagggta tcgaattcga ctactgctgt gtacacgcct
    19801 cgctggcgct gcgcgaagat ggttatgaaa ccattatggt taactgtaac ccggaaaccg
    19861 tctccaccga ctacgacacc tctgaccgtc tctacttcga gccggtaacg ctggaagacg
    19921 tgctggaaat tgtgcgtatt gagaagccga aaggcgttat cgtccagtac ggcggtcaga
    19981 ccccgctgaa actggcgcgc gcgctggaag ctgctggcgt accggttatc ggtaccagcc
    20041 cggatgccat cgaccgtgcg gaagaccgtg aacgcttcca gcatgcggtt gagcgtctga
    20101 aactgaaaca acctgcgaac gccaccgtta ccaccatcga aatggcggtt gagaaagcga
    20161 aagagattgg ctacccgctg gtggtgcgtc cgtcttacgt tctcggcggt cgggcgatgg
    20221 aaatcgtcta tgacgaagct gacctgcgtc gctacttcca gacagcggtc agcgtatcta
    20281 acgatgcgcc agtgttgctg gaccacttcc ttgatgacgc agtagaagtt gacgtggatg
    20341 ccatctgcga cggcgaaatg gtgctgattg gcggcatcat ggagcatatt gagcaggcgg
    20401 gtgtgcactc cggtgactcc gcatgttcac tgccagccta caccttaagt caggaaattc
    20461 aggatgtgat gcgccagcag gtgcagaaac tggccttcga actgcaggtg cgcggcctga
    20521 tgaacgtgca gtttgcggtg aaaaacaacg aagtctacct gattgaagtt aacccgcgtg
    20581 cggcgcgtac cgttccgttc gtctccaaag ccaccggcgt accgctggca aaagtggcgg
    20641 cgcgtgtgat ggctggcaaa tcgctggctg agcagggcgt aaccaaagaa gttatcccgc
    20701 cgtactactc ggtgaaagaa gtggtgctgc cgttcaataa attcccgggc gttgacccgc
    20761 tgttagggcc agaaatgcgc tctaccgggg aagtcatggg cgtgggccgc accttcgctg
    20821 aagcgtttgc caaagcgcag ctgggcagca actccaccat gaagaaacac ggtcgtgcgc
    20881 tgctttccgt gcgcgaaggc gataaagaac gcgtggtgga cctggcggca aaactgctga
    20941 aacagggctt cgagctggat gcgactcacg gcacggcgat tgtgctgggc gaagcgggta
    21001 tcaatccgcg tctggtgaac aaggtgcatg aaggccgtcc gcacattcag gaccgtatta
    21061 agaatggcga atatacctac atcatcaaca ccacctcagg tcgtcgtgcg attgaagact
    21121 cccgcgtgat ccgtcgcagt gcgctgcaat ataaagtgca ttacgacacc accctgaacg
    21181 gcggctttgc caccgcgatg gcgctgaatg ccgatgcgac cgaaaaagta atttcggtgc
    21241 aggaaatgca cgcgcagatc aaataatagc gtgtcatggc ggatattttt catccgctaa
    21301 tttgatcaaa taactaatac ggttctctga tgaggaccgt tttttttgcc cattaagtaa
    21361 atcttttggg gaatcgatat ttttgatgac ataagcagga tttagctcac acttatcgac
    21421 ggtgaagttg catactatcg atatatccac aattttaata tggccttgtt taattgctgc
    21481 aaaacgagtc atagccagtc ttttaatttg tgaaactgga gttcgtatgt gtgaaggata
    21541 tgttgaaaaa ccactctact tgttaatcgc cgaatggatg atggctgaaa atcggtgggt
    21601 gatagcaaga gagatctcta ttcatttcga tattgaacac agcaaggcgg ttaataccct
    21661 gacttatatt ctgtcggaag tcacagaaat aagctgcgaa gttaagatga tccctaataa
    21721 gctggaaggg cggggatgcc agtgtcagcg actggttaaa gtggttgata tcgatgagca
    21781 aatttacgcg cgtctgcgca ataacagccg ggataaatta gtcggcgtaa gaaagacgcc
    21841 gcgtattcct gccgttccgc tcacggaact taaccgcgag cagaagtggc agatgatgtt
    21901 gtcaaagagt atgcgtcgtt aatgtcattt cgttgatacc acgcagcctg gttgccggat
    21961 gcgatgctgg cgcatcttat ccggcctacg gttgctttcc agccaggtcg gataaggcgt
    22021 ttacgccgca tccggcaaga tcaccgtttc ggcgtcacat ccgtcgtccc ctgcaaacgg
    22081 gggcgatttt cctccatttg cctcagtggc tgcgtttcat gtaacgatgc atgacagcgc
    22141 ccgacaagat cctgatactc tttggtattc aaccgtttcc agtgtaactc gtcgtcactc
    22201 acgctgcgta cagcgcgggc tggcgtaccc atcaacaact ggcgtttctc gccgcgaaag
    22261 cccgctttga caaagctcat agcggcaaca atgctctctt cgccaatgac cgcgccatcc
    22321 ataatcacgc tgttcatccc gaccagtgca tcgcgaccaa tcacacaacc atgcaggatc
    22381 gctccgtgcc cgatatgacc gttttcccca acgatggtgt cagtgtcgca gtagccatgc
    22441 ataatgcagc catcctgaat attggctccc gctagcacga tcaaccgccc gtagtcacca
    22501 cgcagtgagg cgagtgggcc gatgtagaca ccggctccca caatcacatc gccaatcaat
    22561 actgcactgg gatggacaaa cgccgtcggg tgaacaaccg gaattaaccc ctcaaaggcg
    22621 taatagctca cggttgttaa cgtcctttcc acactggatc gcgcttctcg gcaaacgcca
    22681 gcggcccttc aatggcatct tccgaatgca gaaccgatgg atagtgtttc aacacgccgc
    22741 tgcgaatata gcgatacgct tcttctaccg gcatttcgct ggtggtgcgg tagatctctt
    22801 tcagcgccgc aatcgccagc ggagcgctgt taaccagctg ctgcgccagt tcgcgggcgt
    22861 tatccatcag ttccgcctgg ctaaccacgc ggttgactac cccccaacgc agcgcctctt
    22921 ctgcgcccat tcgtctgccg gtcatcacca tttcattgac gatggcaggc ggcaggatct
    22981 tcggcagacg cagcacgccg ccgctgtcag gaacgatgcc cagtttggct tccggtaggg
    23041 cgaagctggc gttatcggca caaacaataa aatctgccgc cagcgccagt tcaaagccgc
    23101 cgccaaaggc atagccgttc acagcggcga tgaccggttt gtcgagattg aaaatttcgg
    23161 ttaatcccgc aaaacctccc gggccaaagt cagcatccgg tgcttcgcct tctgctgccg
    23221 cttttaaatc ccagcccgcg gaaaagaatt tctctccggc accggtaata atggcgacac
    23281 gtaattgcgg atcgtcacgg aaatttagaa atacttcgcc catttcaaag ctggtttttg
    23341 catcaatagc attcgctttt ggacgatcaa gggtaatttc cagaattgat ccattgcggg
    23401 tcagatgtaa tgattcactc attccttttc tccatttttg ctttttcagg gacgacaaca
    23461 tccctgcaaa aaatgcatat tgttttagag cgtgattatt agctgacagg gtagttccct
    23521 gccgtttcat ttatttcaga ttctttctaa ttattttccc cgagcaatta cgtggcagat
    23581 cttttctgat ctccagataa gagggcactt taaatttcgc catattttgt tcgcagaagc
    23641 ggaaaaattc ctcttcgctc aatgtttcac cttcattcag caccacaaat gctttgatgg
    23701 cttcatcgcg aatcgaatct ttaataccca caaccacgat atcctgaatt ttgggatggg
    23761 tggcgatgat attttcgagc tccacgcagg agacattctc gccaccgcgt ttgatcatat
    23821 tgcagcggcg atcgacgaaa taaaaaaagc cctcttcgtc gcggtatccg gtatcgccgg
    23881 tatgtagcca gccatcggct tccagcactt tcgcagtggc tttcgggttg agaaaatact
    23941 ctttgaagat ggttttccct ggtacgcctt taatacagat ttcaccgatt tcacctgccg
    24001 ggagcgggcg attgtgatcg tcgcggatct ccgcttcgta gcaaaacccc gcccgaccaa
    24061 ttgacggcca gcgtcgttta tcgccagggc gatcgccgat aatgccaaca atggtttccg
    24121 tcatcccgta agacgtcagc aagcggacgc cgaagcgttc acaaaaagcg tctttttcct
    24181 gctctgacag gttgagataa aacatcactt cccgcaggca gtgttgcctg tcattcacag
    24241 aaggtggttg taccatcagg gtacggatca tcatcggaat acattcggta acggtggcac
    24301 ggtacttctg tacctgcccc cagaaggcgc ggacgctgta tttctcgacc agcacaaagg
    24361 tggccccggc agaaaatgcc gccattgccg cagtacactg gcaatcgata tgaaatgcag
    24421 gcattaccgt caggtagatg tcatcatcac gcagtgcgca ctgccaggcg gagtaatatc
    24481 cagcgaagcg caggttgtaa tgagttatca ccaccccttt cggtcgggag gtggtgccgg
    24541 aggtgaagag aatttccgcc gtatcgtcag tcgatagcgg cggtgcatag cacaaggtgg
    24601 caggttgttg atttttcagt tgagtaaacg aactcacgcc atcatcagcg ggaagtgcca
    24661 tatctgtcag gcaaatgtgc cgcaactgag aggcatcttc ctgctgaatc tgttgataca
    24721 taggataaaa ttgcgcactg gtcaccagca ggcacgcctg gctattttgc aggatccacg
    24781 tgctttcttc gcgcaacagg cgggcgttaa tcggcaccat aatcgcgcca atttttgcca
    24841 acccgaacca gcaaaagata aattccgggc agttgtcgag atgtagagca accttgtcgc
    24901 ctttgcgaat ccccagcgta taaaacaggt ttgccgtgcg gttaatctcc tgatttaact
    24961 caagataact ataccggtta acgactccgc tgctggattc acaaatcagc gccgttttat
    25021 gaccgtaaac gtccgccaga tcgtcccaca tttgacgtag atgttgtccg ccaatgatat
    25081 ccattgcacc tctatccatt ttgttcgttt gttattgagc gggcactagt caggcaagct
    25141 gactgacgcc acgcgtttag tcctcaactt tggccagacc tttgctgacc aactcctgaa
    25201 tgtcgttttc gctgtagccg atatttttca aaatggcagc cgtgtccatg ccatgtgagg
    25261 gcattccgcg ccagatttgt ccggggttat ttttgaattt cggcatgata ttcggccctt
    25321 tgcaggtgcg accatccatc gtttgccact gagtgattga ttcgcgagcc acatactgtg
    25381 gattgctttc cagttccggt acggtcagta ctttggcaca ggcgatattc agttcggcaa
    25441 agcgttcttt aacttctgcg atggtatgtg ccgccagcca ggcatcgagt ttctcttcta
    25501 ccagtgggcc gtaagggcat tcgatacggt ggataagctg ggtgccttcc ggaatttctg
    25561 gcgtgccgag cagatgtgcg aggccaatat ctttaaagca ctctgcaatt tgagtaatgc
    25621 ccaccagttc catcacgatg tagccgtcgg cgcatttata cagaccgcaa ccggcgtagt
    25681 agggatcttt ccctttggtc atgcgcgggc acatttcgcc gccgttgaag taatccatca
    25741 tgaagtactg gcccatacgc agcatcactt catacatggc gatgtcgatg ctttcgcctt
    25801 tgccggtttc acgcacttta tgcagtgctg ccagcgccgc cgtggtggca gtcaggccag
    25861 aaaagtaatc ggcggtatac gggaaggcag gcattggctg gtcaacatca ccgttctgaa
    25921 tcaggtaacc actgaaggcc tgggcgatag tgttataggc cggaagattg gtgtactcct
    25981 cggtgccata ctgaccaaaa ccggacaggt gagcgataac cagttttggg ttgtgctgcc
    26041 acaggacttc atcggtaatg ccacgacggg caaaggccgg acctttactg gcttcgatga
    26101 agatatcggt ggtttccatt aatttcagaa acgcttcacg accttcatct ttgaagatat
    26161 ttaacgacag cgcgtgcagg ttgcggcggg aaagttgcgg gtagttcggt tgaacgcgaa
    26221 tggtgtcggc ccaggcgacg ttttcgatcc agataacttc cgcgccccat tctgcgaaca
    26281 tttgtccggc aaacggtccg gcgatttcga taccggagaa gacaacgcgc aatccggaca
    26341 gcggcccgaa tttcggcatg gttagatgat ccattattag ctcctgaaaa atttatgtag
    26401 cgcatgactg ccggatgcgg cgtaaacgcc ttatccggcc gacattcgtg ctcctgtagg
    26461 cctgataaga cgcgtcagcg tcgcatcagg cagcgcacgg acttagcggt attgcttcag
    26521 caccgcgcgg cccagcgtca ggatctgcat ttcgtcagat cctccggaaa cgcggtctac
    26581 acgcaggtca cgccagaagc ggctgatgcg gtgattaccc gcaatcccga caccgcccag
    26641 cacctgcatt gcgctatcca ccacttcaaa tgccgcattg gcgcagaagt atttgcacat
    26701 cgctgcatcg ccagaggtga tggtgccgtt gtctgctttc cacgctgctt catacagcat
    26761 gtttttcatg gagtttaatt tgatcgccat gtgggcgaat ttttcctgaa tcaactggaa
    26821 acgaccaata gcctcgccaa actgcacgcg ctggttggcg tagcgcgccg catcttcaaa
    26881 ggcgcacatc gccgtaccgt agttggtcag ggctaccagg aaacgttcat ggtcgaactc
    26941 ttctttgacg cggttaaagc cgttaccttc ccgaccgaac atgtctttct cgtccagttc
    27001 cacatcgtca aaggtgattt cacagcagct atccatacgc agaccgagct tctcaagttt
    27061 ggtcactttg atgcccggtt tgctcatatc aacaaaccat tcggtgtaga caggtttgtc
    27121 cggagaagcc ccgtcgcgcg ccatcaccac gatgtacggg gtgtaggcgc tgctggtaat
    27181 aaaacactta ctaccattaa gataaatctt accatttcta cgggtataag tcgttttcag
    27241 gctacccacg tcggagcctg cgcccggttc ggtaatcgct gagttccaca tctgcttacc
    27301 ggtgccgcgg aaagccatga tcttgtcgat ctgctcttgc gtaccttcac gcaggaaggt
    27361 gttaaacccg cccggtaact gatacagcac gtaagttggc gctcccagac gacccagttc
    27421 catccacacg gcggcgagag taacaaaccc cgcgtccaga ccaccgtgct cttcagggat
    27481 cagcagactg tcgataccca tatccgccag ggctttgaca aaacgttccg ggtagacgct
    27541 gtcacggtcg cactcggcaa aataggcctc ccagttttcg ctggccatca gttcgcggat
    27601 accggcgaca aacagttcct gctcatcatt taaattaaaa tccatctttc aacctcttga
    27661 tatttttggg gttaattaat atttccagtt ctgtttcgcg tctttaataa aggagagcgt
    27721 caccatgatg ttgacgaaga acagcgggca tcctccggcg ataatggcgg tttgaatcgg
    27781 tttcaggccg ccgagcgcca gcagaacaat gccgataatg ccaaccagaa ctgaccaacc
    27841 aatgcgcacc agcagcgggg gttcttcgcc gtcacgtact tcgcggcaag tggacatcgc
    27901 cagggtataa gagcaggcgt taaccagcgt aacggtggca ataaagcaga ggatgaagaa
    27961 gccccacatg gtggcggtgc tgagtggcag agcggcccag gtttcgatga tggcgcgcgc
    28021 cacaccgtac tgttcgatca gatttggaat gttgatgatg tttttatcta tcaacagcag
    28081 ggtgttacta ccgagtacag tccacaggat ccaggttgac gctgtcagcc ccagcaccat
    28141 gccgaagcac agttcacgca cggtacgacc acgggagatg cgggcgagga agatactcat
    28201 ctggatagcg taaatcaccc accatgccca gtagaacacg gtccagccct gcgggaagcc
    28261 gcctttagcg atgggatcgg tatagaacaa catgcgcggc agatacatca gcaacatccc
    28321 caccgaatcg gtgaagtagt tcatgatgaa gctggcaccg ctgacgatga acacccaacc
    28381 cagcatcagg aagctcaggt aactacgcac gtcactggcg atacgtaccc ctttttgcag
    28441 accgcaagcg acgcaaatgg cgttgaggat aatccagcag gtaatgatga tagcgtccag
    28501 ttgcagggta tgcggaatgc caaacaacca ttgcatacac tcggttacca gcggcgtggc
    28561 aaggcccaga ctggtaccca tcgcgaagat caaggcgacg agatagaagt tgtcgacgat
    28621 agtgccgaac aaccctttgg cgtgtttttc acctaccagc ggcaccaggg tcgagctggg
    28681 gcgaatcact tccattttgc ggacaaagaa gaagtaagcg aaggcgactg aaaggaagct
    28741 gtaagtggcc cacggcagag gtccccagtg gaacaagctg taagccagcc ccaactcttt
    28801 cgcgcctgtt gagttcggtt ctaagccaaa cggcggggtg gagatgtagt agtagatctc
    28861 aatcgatccc cagaacagta cggcagcaga cgtacaggag gcgaacatca taaagatcca
    28921 actggcggta ctaaattctg gtggttcgtt acctaaacgc tttttggcat acgggccaaa
    28981 caccagccag aaccagccga aaagcatcac caccatatac cattcaaatg cccatcccca
    29041 tacattggtg acgtaactga atacagcatt aataacgaca ttcgctgcat ccagatctct
    29101 gactgtaagc caacaaagta tgccgacgat tattaacggc ggaaagaaaa ccttcggttc
    29161 tattcccgtt tttctctttt cattcttcat gagttaattc cactgtgaaa acgaatattt
    29221 attttgcgtt cccgtttgtt ttatttttgt taacatttaa tataattatt attaacctcg
    29281 tggacgcgtt aatggctaac tcataatggg tattcaataa gctgcattct gtgattgttg
    29341 tcacattttt gtttcgggtg aatagagggc atttttttgt taattttgat tattaatcag
    29401 tttgttatgt tctgttgtgg gtaaaaaaat agcatctgac tttcaatatt ggtgatccat
    29461 aaaacaatat tgaaaatttc tttttgctac gccatgtttt caatattggt gaggagctta
    29521 acaatattga aagttggatt tatctgcgtg tgacattttc aatattggtg attaaagttt
    29581 tatttccaaa ttaaagggcg tgatatctgt aattaacacc accgatatga acgacgtttc
    29641 cttcatgatt tctggagatg caatgaagat tattacttgc tataagtgcg tgcctgatga
    29701 acaggatatt gcggtcaata atgctgatgg ttcgttagac ttcagcaaag ccgatgccaa
    29761 aataagccaa tacgatctca acgctattga agcggcttgc cagctaaagc aacaggcagc
    29821 agaggcgcag gtgacggcct taagtgtggg cggtaaagcc ctgaccaacg ccaaagggcg
    29881 taaagatgtg ctatcgcgcg gtccggatga actgattgtg gtgattgatg accagttcga
    29941 gcaggcactg ccgcaacaaa cggcgagcgt acttgctgca gccgctcaga aagcaggctt
    30001 tgatttgatc ctctgtggcg atggttcttc cgacctttat gcccagcagg ttggtttgct
    30061 ggtaggcgaa atccttaata ttccggcagt taacggcgtc agcaaaatta tctccctgac
    30121 ggcagatacc ctcaccgttg agcgcgaact ggaagatgaa acagaaacct taagcattcc
    30181 gctgcctgcg gttgttgctg tttccactga tatcaactcc ccacaaattc cttcgatgaa
    30241 agccattctc ggcgcggcga aaaagccagt ccaggtatgg tcggcggcgg atatcggttt
    30301 taacgcagag gcagcctggt cagaacaaca ggttgccgcg ccgaaacagc gcgagcgtca
    30361 gcgcatcgtg attgaaggcg acggcgaaga acagatcgcc gcatttgctg aaaatcttcg
    30421 caaagtcatt taattacagg ggatgctatg aacacgtttt ctcaagtctg ggtattcagc
    30481 gatacccctt ctcgtctgcc ggaactgatg aacggtgcgc aggctttagc taatcaaatc
    30541 aacacgttcg tcctcaatga tgccgacggc gcacaggcaa tccagctcgg cgctaatcat
    30601 gtctggaaat taagcggcaa accagacgag cggatgatcg aagattacgc cggtgtcatg
    30661 gctgacacta ttcgccagca cggcgcagac ggtctggtgc tgttgccaaa cacccgtcgc
    30721 ggcaaattac tggcggcgaa actgggttac cgccttaacg cggcggtgtc taacgatgcc
    30781 agcgctgtta gcgtgcagga cggtaaagcg acagtgaaac acatggttta cggcggtctg
    30841 gcgattggcg aagaacgcat tgccacgccg tatgcggtac tgaccatcag cagcggcacg
    30901 ttcgatgcgg ctcagccaga cgcgtcacgc actggcgaaa cgcacaccgt ggagtggcag
    30961 gctccggctg tggcgattac ccgcacggca acccaggcgc gtcagagcaa cagcgtcgat
    31021 ctcgacaaag cccgcctggt ggtcagcgtc ggtcgcggta ttggcagcaa agagaacatt
    31081 gcgctggcag aacagctttg taaggcgata ggtgcggagt tggcctgttc tcgtccggtg
    31141 gcggaaaacg aaaaatggat ggagcacgaa cgctatgtcg gtatctccaa cctgatgctg
    31201 aaacctgaat tgtacctggc ggtggggatc tccgggcaga tccagcacat ggttggcgct
    31261 aatgcgtcgc aaaccatttt cgccatcaac aaagataaaa atgcgccgat cttccagtac
    31321 gcggattacg gcattgttgg cgacgccgtg aagatccttc cggcactgac cgcagcttta
    31381 gcgcgttgat ccactctggc agggctgcat tccggccctg ccgctgacag ggagctctta
    31441 tgtccgaaga tatctttgac gccatcatcg tcggtgcagg gcttgccggt tcggttgccg
    31501 cactggtgct cgcccgcgaa ggtgcgcaag tgttagttat cgagcgaggc aattccgcag
    31561 gtgccaagaa cgtcactggc gggcgtctct atgcccacag tctggaacac attattcctg
    31621 gtttcgctga ctccgccccc gtagaacgcc tgatcaccca tgaaaaactt gcgtttatga
    31681 cggaaaagtc agcgatgact atggactact gcaatggcga cgaaacctct ccatcccagc
    31741 gttcttactc cgttttgcgc agtaaatttg atgcctggct gatggagcag gccgaagaag
    31801 cgggcgcgca gttaattacc gggatccgcg tcgataacct cgtacagcgc gatggcaaag
    31861 tcgtcggtgt agaagccgat ggcgatgtga ttgaagcgaa aacggtgatc cttgctgatg
    31921 gggtgaattc catccttgcc gaaaagctgg ggatggcaaa acgcgttaaa ccgacggatg
    31981 tggcggttgg cgtgaaggaa ctgatcgagt taccgaagtc ggttattgaa gaccgttttc
    32041 agttgcaggg taatcagggc gcggcttgcc tgtttgcggg atcacccacc gatggcctga
    32101 tgggcggtgg cttcctttat accaatgaaa ataccctgtc gctggggctg gtttgtggtc
    32161 tccatcatct gcatgacgca aaaaaatcgg tgccgcaaat gctggaagat ttcaaacaac
    32221 atccggccgt tgcaccgctg atcgcgggcg gcaagctggt ggaatattcc gctcacgtag
    32281 tgccggaagc aggcatcaac atgctgccgg agctggtcgg tgacggcgta ttgattgccg
    32341 gtgatgctgc cggaatgtgt atgaacctcg gttttaccat tcgcggtatg gatctggcga
    32401 ttgccgccgg ggaagcagca gcaaaaactg tgctttcagc gatgaaaagc gacgatttca
    32461 gtaagcaaaa actcgcggaa tatcgtcagc atcttgagag tggcccgctg cgcgatatgc
    32521 gcatgtacca gaaactaccg gcgttccttg ataacccacg catgtttaac ggctacccgg
    32581 aactggcggt gggcgtggcg cgtgacctgt tcaccattga cggcagtgcg ccggaactga
    32641 tgcgcaagaa aatcctccgc cacggcaaga aagtgggctt catcaatctg atcaaggatg
    32701 gcatgaaagg agtgaccgtt ttatgacttc tcccgtcaat gtggacgtca aactgggcgt
    32761 caataaattc aatgtcgatg aagagcatcc gcacattgtt gtgaaggccg atgccgataa
    32821 acaggccctg gagctgctgg tgaaagcgtg ccccgcaggt ctgtacaaga agcgggatga
    32881 cggcagtgtg cgcttcgatt acgccggatg tctggagtgc ggcacctgtc gcattctggg
    32941 gctggggtcg gcgctggaac agtgggaata cccgcgcggc acctttggtg tggagttccg
    33001 ttacggctga tgttggtttg atacgtaatg ccgtactgac tctcattgca aaaaaacagg
    33061 aataacccat gcaaccgtcc agaaactttg atgatcttaa attctcctct attcaccgcc
    33121 gcattttgct gtggggaagc ggtggtccgt ttctggatgg ttatgtactg gtaatgattg
    33181 gcgtggcgct ggagcaactg actccggcgc tgaaactgga cgctgactgg attggcttgc
    33241 tgggcgcggg aacgctcgcc gggctgttcg ttggcacatc gctgtttggc tatatctccg
    33301 ataaagtcgg acggcgcaaa atgttcctca ttgatatcat cgccatcggc gtgatatcgg
    33361 tggcaacgat gtttgtctca tcccccgtcg aactgttggt gatgcgggta cttatcggca
    33421 ttgtcattgg tgcggattat cccatcgcca cctcaatgat caccgagttc tccagtaccc
    33481 gtcagcgggc gttttccatc agctttattg ccgcgatgtg gtatgtcggc gcgacctgcg
    33541 ccgatttggt cggctattgg ctttatgatg tggaaggcgg ctggcgctgg atgctgggta
    33601 gcgcagcgat tccctgtttg ttgattttga ttggtcgatt cgaactgcct gaatctcccc
    33661 gctggttgtt acgcaaaggg cgagtaaaag agtgcgaaga gatgatgata aaactgtttg
    33721 gcgaaccggt ggctttcgag gaagagcagc cgcagcaaac ccgttttcgc gatctgttta
    33781 atcgccgcca ttttcctttt gttctgtttg ttgccgctat ctggacctgc caggtgatcc
    33841 ccatgttcgc catttacacc tttggcccgc aaatcgttgg tttgttggga ttgggggttg
    33901 gcaaaaacgc ggcactgggg aacgtggtga ttagcctgtt ctttatgctc ggctgtattc
    33961 cgccgatgct gtggctaaac actgccggac ggcgtccatt gttgattggc agctttgcca
    34021 tgatgacgct ggcgctggcg gttttggggc tgatcccgga tatggggatc tggctggtag
    34081 tgatggcctt tgcggtgtat gcctttttct ctggcgggcc gggtaatttg cagtggctct
    34141 atcctaatga actcttcccg acggatatcc gcgcctctgc cgtgggcgtg attatgtcct
    34201 taagccgtat tggcactatt gtatcgacct ggacactgcc gatctttatc aataattacg
    34261 gtatcagtaa cacgatgcta atgggggcgg gtatctcgct atttggcttg ttgatttccg
    34321 tagcgtttgc cccggagact cgagggatgt cactggcgca gaccagcaat atgacgatcc
    34381 gcgggcagag aatggggtaa tttgttcaga tttctctctt ttctgaatca atattattga
    34441 ctataagctg cgtgaatata tgactacact ttgtgggaaa acaaaggcgt aatcacgcgg
    34501 gctacctatg attcttataa tttatgcgca tccatatccg catcattccc atgcgaataa
    34561 acggatgctt gaacaggcaa ggacgctgga aggcgtcgaa attcgctctc tttatcaact
    34621 ctatcctgac ttcaatatcg acattgccgc cgaacaggag gcgctgtctc gtgccgatct
    34681 gatcgtctgg cagcacccga tgcagtggta cagcattcca ccgcttctta aactttggat
    34741 cgataaagtt ttctcgcacg gctgggctta cggtcacggc ggcacggcgc tgcacggcaa
    34801 acatttgctg tgggcggtga cgaccggcgg cggggaaagc cattttgaga ttggtgcgca
    34861 tccgggcttt gatgtgctgt cgcagccgct acaggcgacg gcaatctact gcgggctgaa
    34921 ctggctgcca ccgtttgcca tgcactgcac ctttatttgt gacgacgaaa ccctcgaagg
    34981 gcaggcgcgg cactataagc aacgtctgct ggaatggcag gaggcacatc atggatagcc
    35041 atacgcttat tcaggcgctg atttatctcg gttcggcggc gctgattgtt cccattgcgg
    35101 tacgtctcgg tctgggatcg gttcttggct acctgatcgc cggctgcatt attggcccgt
    35161 gggggctgcg actggtgacc gatgccgaat ctattctgca ctttgcagag attggcgtgg
    35221 tgctgatgct gtttattatc ggcctcgaac tcgatccaca aaggctgtgg aagctgcgtg
    35281 cggcagtgtt cggcggtggc gcattgcaga tggtgatttg cggcggcctg ctggggctgt
    35341 tttgtatgtt acttgggctg cgctggcagg tcgcagaatt gatcggcatg acgctggcgc
    35401 tctcatcaac ggcgattgcc atgcaggcga tgaatgaacg caatctgatg gtgacgcaaa
    35461 tgggccgcag agcctttgcg gtgctgctgt tccaggatat cgcggcgatc ccactggtgg
    35521 cgatgatccc gctactggca gcgagtagtg cctcgacgac gatgggcgca tttgttctct
    35581 cggcgttaaa agtggcgggc gcgctggtgc tggtggtatt gctggggcgc tatgtcacgc
    35641 gtccggcact gcgttttgtt gcccgctctg gcttgcggga agtgtttagt gccgtggcgt
    35701 tattcctcgt gtttggcttt ggtttgctgc tggaagaggt cggcttgtcg atggcgatgg
    35761 gcgcgtttct ggcgggcgta ctgctggcaa gctcggaata ccgtcatgcg ctggaaagcg
    35821 atatcgaacc atttaaaggt ttgctgctgg ggctgttttt catcggcgtt ggcatgtcga
    35881 tagactttgg cacgctgctt gaaaatccgt tgcgcattgt cattttgctg ctcggtttcc
    35941 tcatcatcaa aatcgccatg ctgtggctga ttgcccggcc gttgcaggtg ccaaataaac
    36001 agcgtcgctg gtttgcggtg ctgttagggc agggcagtga gtttgccttt gtagtatttg
    36061 gtgcggcgca gatggcgaat gtgctggagc cagagtgggc gaaatcgctg accctggcgg
    36121 tggcactgtc gatggcggca acgccgattc tgctggtgat cctcaatcgc cttgagcaat
    36181 cttctactga agaggcgcgt gaagccgatg agatcgacga agaacagccg cgggtaatca
    36241 ttgccggatt cggtcgtttt gggcagataa ccggacgttt actgctctcc agcggggtga
    36301 aaatggtggt gctcgatcac gacccggacc atatcgaaac gctgcgtaaa ttcggtatga
    36361 aagtgtttta tggcgatgcc acgcggatgg atttactgga atctgccgga gcggcgaaag
    36421 cggaagtgct gattaacgcc atcgacgatc cgcaaaccaa cctgcaactg acggagatgg
    36481 tgaaagaaca tttcccacat ttgcagatta ttgcccgcgc ccgcgatgtc gaccactaca
    36541 ttcgtttgcg tcaggcaggc gttgaaaagc cggagcgtga aaccttcgaa ggtgcgctga
    36601 aaaccgggcg tctggcactg gaaagtttag gtctggggcc gtatgaagcg cgagaacgtg
    36661 ccgatgtgtt ccgccgcttt aatattcaga tggtggaaga gatggcaatg gttgagaacg
    36721 acaccaaagc ccgtgcggcg gtctataaac gcaccagcgc gatgttaagt gagatcatta
    36781 ccgaagaccg tgaacatctg tcattaattc aacgacatgg ctggcaggga accgaagaag
    36841 ggaaacatac tggcaatatg gcggatgaac cggaaacgaa gccctcatcc taataaagag
    36901 tgacgtaaat cacgctttac agctaactgt ttgtttttgt ttcattgtaa tgcggcgagt
    36961 ccagggagag agcgtggact cgccagcaga atataaaatt ttcctcaaca tcatcctcgc
    37021 accagtcgac gacggtttac gctttacgta tagtggcgac aatttttttt atcgggaaat
    37081 ctcaatgatc agtctgattg cggcgttagc ggtagatcgc gttatcggca tggaaaacgc
    37141 catgccgtgg aacctgcctg ccgatctcgc ctggtttaaa cgcaacactt taaataaacc
    37201 cgtgattatg ggccgccata cctgggaatc catcggtcgt ccgttgccag gacgcaaaaa
    37261 tattatcctc agcagtcaac cgggtacgga cgatcgcgta acgtgggtga agtcggtgga
    37321 tgaagccatt gcggcgtgtg gtgacgtacc agaaatcatg gtgattggcg gcggtcgcgt
    37381 ttatgagcag ttcctgccga aagcgcaaaa actgtatctg acgcatatcg acgcggaagt
    37441 ggaaggcgac acccatttcc cggattacga gccggatgac tgggaatcgg tattcagtga
    37501 attccacgac gccgatgcgc agaactctca cagctattgc tttgagattc tggagcggcg
    37561 gtaatttcgt atattagaat tccggcatca ctgatacgtg cagatatccg tgtatactag
    37621 acgtataaat tgtacaggag cacgagatca tgactgcaaa acgtaccaca caaagtgtga
    37681 ccgtcaccgt cgaccgtgag ttagtcaatc gcgctcgtga tgcaggctta aatatgagcg
    37741 ccacccttac ggttgcgctc aatgctgaac ttaaaaaaca tgcagcaaca cgttggcgtg
    37801 aagagaacgc agaagctatc gctgcgttaa atcaattggc tgatgaaacc ggatgtttct
    37861 ctgatgagta ccggagcttc tagcgatgca atttacggta taccgcagtc gcggcaggaa
    37921 cgccgcgttt ccctttgtta ttgatgttac cagcgacatt attggtgaga ttaatcgccg
    37981 tatcgttatt ccattaacac ctattgaacg atttagccgt attcgcccac cagaacggct
    38041 taacccaatc cttttactga tagacggcaa agaatatgtg ctcatgacgc atgagactgc
    38101 aactgttcca gttaacgcgc tgggaacgaa attttgcgat gccagcgcgc accgaacgtt
    38161 gattaaatga gcattagatt ttatgctcga cgggatttaa gacgctaccg cctctccctc
    38221 actcaaatcc ttatgccggt tcgacggctg gacaaaatac tgtttatctt cccagcgcag
    38281 gcaggttaat gtaccacccc agcagcagcc ggtatccagc gcgtaaatac cttccggcgt
    38341 acctttgcct tccagcgatg cccagtgacc aaaggcgatg ttgtactctt cagcgacggg
    38401 gccaggaatc gcaaaccacg gtttcagtgg ggcaggggcc tcttccggcg attctttgct
    38461 gtacatatcc agttgaccgt tcgggaagca aaaacgcata cgggtaaagg cgttggtgat
    38521 aaaacgcagt cttcccagcc cccgcaattc cggtgaccag ttatttggca tatcgccgta
    38581 catggcatca aggaagaagg gataggagtc actcgacagc accgcttcta catcgcgcgc
    38641 gcactctttg gcggtctgca gatcccactg cggcgtgatc ccggcgtggg ccatcaccaa
    38701 ctttttctct tcgtcgattt gcagcaaagg ctggcgacgc agccagttaa gcagctcgtc
    38761 ggcatccggc gcttccagca gcggtgtcag gcgatctttc ggtttattgc ggctgatccc
    38821 ggcaaatacc gccagcagat gcagatcgtg attacccagc accagacgta cgctgtcgcc
    38881 taaggatttc acatagcgca gaacatccag cgaacccggg ccgcgcgcga ccagatcgcc
    38941 cgtcagccag agggtatctt tcccaggggt aaattctact ttatgcagca atgcgatcag
    39001 ttcatcgtaa caaccatgaa cgtcgccaat aaggtatgtc gccatattct tttaatgaat
    39061 gagtgtggga acggcgagtc ggaatacggg aatgtcgatg ctgaaaggga cgccattttc
    39121 atcgatcatt tcgtagtgac cctgcatggt gcccagcggg gtttcaatga ttgcaccgct
    39181 ggtgtactgg tactcttcgc caggcgcgat aagtggctgg acgccaacca ctccttcgcc
    39241 ctggacttcg gtttcacggc cattgccatt ggtgatcagc cagtaacgcc ccaacaactg
    39301 cactggcgct cgccccagat tgcgtatggt tacggtataa gcaaaaacgt aacgttcatt
    39361 atcaggtgaa gattgggcct caatgtagac gctttgaacc tgaatacaca ctcggggcga
    39421 attgatcatc gttaactctc ctgcaaaggc gcgttctccg ccagatagtt cgccatctgg
    39481 caatattgcg cgacagagat attttccgct cgcatcgccg ggtcgatccc cattcccgtt
    39541 aacaccccga cgctaaacag gttgccgagg ctgttacgaa tggttttacg acgctggtta
    39601 aaggcttcgg tggtgatgcg gctcaacacg cgaacatctt taaccgggtg aggcatcgtt
    39661 gcatgaggaa ccaggcgcac gacggcggaa tccactttgg gtggtggtgt aaaggctgac
    39721 ggcggtactt ccagcaccgg gatcacgttg caatagtatt gcgccatgac gcttaatcga
    39781 ccatacgcct tgctgttcgg tcctgcaacc agacgattca ccacttcttt ttgcaacata
    39841 aagtgcatgt cggcaatggc atcagtatag ctaaacagat ggaacatcaa cggcgtggag
    39901 atgttataag gcaggttgcc gaaaacacgc agcggctggc ccattttcgc ggccagttca
    39961 ccaaagttaa aggtcatcgc atcctgctga taaatcgtca gtttcgggcc taagaatgga
    40021 tgcgtttgca gacgtgccgc cagatcgcgg tcaagttcga tgaccgtcag ctggtccaga
    40081 cgttcgccga ccggttcggt caatgccgcc agaccggggc cgatttcgac catcgcctgg
    40141 cccttctgcg ggttaatggc agaaacaatg ctgtcgatca cgaactgatc gttgagaaag
    40201 ttttgcccga agcgtttacg ggctaagtgg ccctggtgga ctcgattatt cattgggtgt
    40261 taacaatcat tttgatggcg agattaagcg ccgtaataaa actgccgaca tcggctttac
    40321 cacgtcccgc cagttcaagc gcggtgccgt ggtccactga tgtgcgaata aagggcaggc
    40381 ccagcgtaat gttcacaccg cgcccgaagc cctggtattt tagcacggga agaccctgat
    40441 cgtggtacat cgccagcacg gcgtcggcgt tatcgagata tttcggctga aacagggtat
    40501 cggcaggcag cggcccgttg agtttcatcc cctgttcccg cagctcgtcg agtaccggaa
    40561 taatggtgtc tatctcttcc gtacccatat gaccgccttc gcccgcgtgc ggattcagcc
    40621 cgcagaccag aatgcgcggt tcggcaatac caaatttggt ccgcaaatcg tgatgcaaaa
    40681 tagcaatcac ttcgtgcaaa agggcagggg tgatagcatc tgcgatatcg cgcagcggta
    40741 aatgcgtcgt tgccagcgcc acgcgaagtt cttcggtcgc cagcatcatc accacttttt
    40801 tcgcctgcga acgctcttcg aaaaactcgg tatgaccggt aaacggaatg cctgcgtcgt
    40861 taatgacgcc tttatgcacg gggcctgtga tcagcgcagc aaattcaccg ttcagacagc
    40921 catcacacgc tcgcgccagc gtttccacca catagtgccc attttcaacc gctaacagcc
    40981 ccacagtgac agattcacgt agcgcgacag gaagtagcgt taatgtgccc gcagtttgcg
    41041 gttgtgcagg ggagttgggg gaataagggc ggagggtgag cggcaaaccg agcatcgctg
    41101 cccggtcggt aaggagagtg gcatcggcac aaacaaccag ttcgaccggc cactcacgct
    41161 gtgcaagctg gacaattaag tccgggccaa tcccggcggg ctcgccggga gtgatcacaa
    41221 cacgttgggt tttaaccatt agttgctcag gattttaacg taggcgctgg cacgttgttc
    41281 ctgcatccag cttgctgctt cttccgagaa cttacggttc atcagcatgc ggtatgcacg
    41341 atctttctgt gccgcgtcgg ttttatcgac attacgggta tccagcagtt cgattaaatg
    41401 ccagccgaat gaagagtgaa ccggtgcact catttgacct ttgttcaggc gggtcagggc
    41461 gtcacggaag gccggatcga aaatatctgg tgtagcccag ccgagatcac cgccctggtt
    41521 agcagagcct ggatcctgag agaactcttt cgctgcggca gcaaaagtcg ttttaccact
    41581 cttgatatcg gcagcaatct gttccagttt cacgcgggcc tgttcgtcag tcatgatcgg
    41641 cgacggtttc agcagaatat ggcgagcatg aacttcggtc accgagatat ttttgctttc
    41701 gccgcgcagg tcgttaactt tcagaatatg gaagccaacg ccggaacgaa tcgggccaac
    41761 aatgtcgcct ttcttcgcgg tgcttaatgc ctgggcgaag atccccggca actcctgaat
    41821 acggccccag cccatctggc cgccgttcag cgcctgctgg tcggcagaat gagcaatcgc
    41881 cagcttaccg aaatcagcgc cgttacgcgc ctgatcgaca atcgcgcgcg cctggctttc
    41941 cgcttcgttc acctgatcag aggtcgggtt ttccggcagc gggatcagga tgtggctcag
    42001 gttcagctca gtgctggcgt cgttttggtt acccacttgc tgcgccaggg attcgacttc
    42061 ctgcggcagg atggtgatgc gacgacgcac ctcgttgtta cgcacttcag agataatcat
    42121 ctctttgcgg atctggttac gataggtgtt gtagttcaga ccatcgtaag ccagacggct
    42181 gcgcatctga tccagcgtca tgttgttctg tttcgcgatg ttagcaatcg cctgatccag
    42241 ctgctcatcg gagattttca ctcccatttt ctgccccatc tgcaggataa tttgatccat
    42301 gatcaaacgt tccatgattt ggtggcgcag cgtcgcgtca tcaggaagtt gttgccttgc
    42361 ctgagcagcg ttcagtttta ccgactgcat taatccatca acgtcgcttt ccagcacgac
    42421 gccgttattg acgacggctg cgactttatc gactacctgg ggggcagcga aactggtatt
    42481 cgcgatcatg gcgataccga gaagcagcgt tttccagttc ttcatacttt ttccatttca
    42541 attaaccgca ctgcggatta cgtggtaaat caacaaatca caaagtgttt tgatacggca
    42601 gaatgttcga acgcagcatc tcttgcgtac ccagaccgta gttggagctc aggccgcgaa
    42661 gttcgatgtt aaagccgatt gcgttgtcat ataccgcatg ttgtttatcg ttatcccaac
    42721 cgttcagctt ccgctcgtaa ccgacgcgaa tcgcatagca gcaggagctg tattgcacac
    42781 ctaacataga gtcggcttgc ttgttcgcat tggtgtcgta gtagtaggcc ccaacaatgg
    42841 accaacgatc ggcaattggc cagctggcga cggcacctac ctgcgaaata ccattcttat
    42901 attgctcagc agtggaatag tacttaggca gcgtagcctg aatatattcc gggctggcgt
    42961 aacggtaatt cagctgtacc agacggtctt catcacgacg gtattcaatg ctggagttac
    43021 tggtcgctac gttatccaga cgtgtatcgt actgaatccc gccacgcaat ccccaacgat
    43081 cggagatgcg ccagtaagta tcgcctgccc ataccagtga gcccgttttg tcgtcattct
    43141 cccatgttat gttgtcatcg ccagtgcgag actccgtgaa atagtagatt tgaccaacgg
    43201 aaatattaaa acgttcaacg gcagcatcat catatatgcg agatgtgaca ccggtcgtca
    43261 cctggttagc ggaggcaata cggtcaagac cgccgtaagt ccggtcccgg aacaggccgg
    43321 agtagtcaga ttgcagcagc gaagagtcgt agttatagat tttgctctga tcgcgatatg
    43381 gcacatacag atactgcgcg cgtggttcca gtgtctgggt atagcccggc gccagcattt
    43441 ccatatcacg ctcgaagacc attctaccgt ctaccttgaa ctgcggcatt acacggttag
    43501 cggactctgc cagcctggtc gtgtttctgg agttatacca gtcaagattg gtttgctgat
    43561 aatgggttgc cagcaacttc gcttcggtat tgatgctgcc ccagttatta gagagcggca
    43621 gattgatggt cggttccagg tgaacacggg ttgcttcagg catgtcgtct ctggtgttaa
    43681 caaagtgcac tgcctgaccg taaatacgcg tatcaaacgg accaacatca ttctggtagt
    43741 agttaacgtc taactgcggc tctgccgagt agctactggt gttctgctcg ctgaagacct
    43801 ggaactgctt ggttgaaacg gtggcattga agttttgcac cgcatagcca acgctgaatt
    43861 tttgcgttgc gtagccgtcg gtactggaac cgtatttgtt atcgaagtca ttgaagtagc
    43921 taggatcgct gactttggtg tagtcgacgt tgaaacgcca cacctgatcc atgaccccgg
    43981 agtggttcca gtagaacaac caacgacgtg aactgtcatc gttcgggtgt tcatctttat
    44041 agactttatc tgaaggcaga tagtccagtt ccatcaagcc agcgcccgcc tgggagaggt
    44101 agcggaattc gttctcccac atgatgttgc cacgacgatg catataatgc ggcgtgatgg
    44161 tggcatccat atttggcgcg atgttccagt aatatggcag gtagaactca aagtagttgg
    44221 tggtggtgta cttggcgttc gggatcaaga aaccagagcg acgtttgtca cccaccggca
    44281 actgcaaata cgggctataa aagatcggta ccggacccac cttaaagcgg gcgttccaga
    44341 tctccgcaac ttgttcttcg cggtcatgaa taatttcgct acctaccacg ctccaggtgt
    44401 cagaacccgg cagacaggag gtaaagctac cgttatccag aatggtatag cggttttcgc
    44461 cacgttgttt catcaggtcc gctttaccgc gcccctggcg acccaccatc tggtaatcac
    44521 cttcccagac gttggtatct ttggtgttca gattcgccca gcctttcggc cctttgagga
    44581 tcacctggtt atcgtcgtaa tggacattac cgagcgcatc aacggtacgt accggctccg
    44641 gttgtcctgg tgcctctttt tgatggagct gcacttcgtc ggcctgcaga cggctgttac
    44701 cctgcatgat atccacgctg ccagtaaaca cggcgtcatc cgggtagtcc cctttcgcgt
    44761 ggtcagcatt gatagtcacg ggtaagtcat tggtatcgcc ctgtaccaga ggacggtcat
    44821 agcttggcac gcccaacatg cactgtgagg cgaggtcggc tgccagtccc tgttgactat
    44881 aaagggcggt ggcaatcatg gtggccagga gagtggggat acgttttttc atacgttgat
    44941 tttattgttc catcatcggt aacgttgcgc gtgacaaacg gtcagagact aacgtactcg
    45001 tcatctctac gctagtgtta atcctgtccg aatagcgtca gtggtgttag gcacggcatt
    45061 gaatgacagg tatgataatg caaattatag gcgatgtccc acaattgacc gcagccggaa
    45121 aacggtaaaa gcacctttat attgtgggag atagccctga tatccgtgtg tcgatttggg
    45181 gaatatatgc agtattgggg aaaaatcatt ggcgtggccg tggccttact gatgggcggc
    45241 ggcttttggg gcgtagtgtt aggtctgtta attggccata tgtttgataa agcccgtagc
    45301 cgtaaaatgg cgtggttcgc caaccagcgt gagcgtcagg cgctgttttt tgccaccact
    45361 tttgaagtga tgggccattt aaccaaatcc aaaggtcgcg tcacggaggc tgatattcat
    45421 atcgccagcc agttgatgga ccgaatgaac cttcatggcg cttcccgtac tgcggcgcaa
    45481 aatgcgttcc gggtgggaaa atcagataat tacccgctgc gcgaaaagat gcgccagttt
    45541 cgcagtgtct gctttggtcg ttttgactta attcgtatgt ttctggagat ccagattcag
    45601 gcggcgtttg ctgatggttc actgcacccg aatgaacggg cggtgctgta tgtcattgcc
    45661 gaagagttag gcatctcccg cgcccagttt gaccagtttt tgcgcatgat gcagggcggt
    45721 gcacagtttg gcggcggtta tcagcagcaa tctggcagtg gtaactggca gcaagcgcag
    45781 cgtggcccga cgctggaaga tgcctgtaat gtgctgggcg tgaagccgac ggatgatgcg
    45841 accaccatca aacgtgccta ccgtaagctg atgagtgaac accatcccga taagttggtg
    45901 gcgaaaggtt tgccgcctga gatgatggag atggcgaagc aaaaagcgca ggaaattcag
    45961 caggcctatg agctgataaa gcagcagaaa gggtttaaat aagtttcaac gtgtaggcct
    46021 gataagacgc ggtaggccgg ataagacgcg ccagcgtcgc atccggcgag cagcatcaga
    46081 caatcggcgc acaattgccg gatgtggcgt gaacgcctta tccggcctac cgaacttcgc
    46141 cagcgtgact attaaaaatc cgctggtgct ttaaacgtca tactattgcc atacgccgga
    46201 tgggtaatcg tcagcatctc tgcatgtagc aacaaacgcg gtgccattgc tctcgcttct
    46261 ggtgatgcat aaaaacgatc gccgagaatc ggatgaccca gcgccagcat atgcacacgc
    46321 agctgatgcg aacgcccggt aatcggtttt aacaccactc ttgccgtgtt atccgccgca
    46381 tattccacca cttcatactc cgtctgcgca ggtttacctg tttcgtaaca gactttctgt
    46441 ttcgggcggt ttggccagtc gcaaatcagc ggcagatcca ccagaccttc cgcaggggat
    46501 ggatgccccc agacgcgggc cacatactgt tttttcggct cgcgctcgcg gaactggcgt
    46561 tttaactccc gctccgcggc tttggtcagc gccactacaa tcacgccgct ggtagccata
    46621 tccagacgat gcaccgattc tgcctgcgga taatcacgct gaatgcgcgt catcacgctg
    46681 tctttgtgct cttccagacg acccggcaca gacaacaaac cgctcggctt gttgaccacc
    46741 ataatatggt catcctgata caggacaacc agccagggtt cctgcggcgg attgtagttt
    46801 tccatcccca tcttcggctc cgttactgat gcgtcacaac gatcaaacgc agggcatcca
    46861 gacgccagcc tgcctgatcc aggctttcca ttacctgctg acggttgctc tcaatggcgg
    46921 tcagttcgtc gtcacgaatg ttcgggttaa ctgcacgcag cgcttccaga cgagacagct
    46981 cggcagacag tttttcgtcg gcttcgttac gcgctgcatc aatcaatgca cgggcagatt
    47041 tctcgatctg cgcttccccc agctgaagga tagcgtgaac atcctgctgc accgcgttaa
    47101 ccagcttgct gccggtgtga cggttaaccg cgttaagctg acggttaaag gtttcaaatt
    47161 ctacctgcgc cgccaggttg ttgccgtttt tatccagcag catacgtacc ggcgtcggtg
    47221 gcaggaagcg gttgagctgc aactgcttcg gagcctgggc ttcaaccaca taaatcagtt
    47281 ccaccaacag cgtacctacc ggcaacgctt tgtttttcaa cagtgaaatc gtgctgctac
    47341 cggtatcgcc agaaaggatc agatccagac cgttgcggat cagcggatgc tcccaggtaa
    47401 taaactgtgc atcttcacgc gccagcgcca cttcacggtc gaaggtgatg gtgatgccat
    47461 cttccgacag gccagggaag tccggcacca gcatatgatc ggacggcgtc agcacgatca
    47521 tgttgtcgcc gcgatcgtcc tgattgatac cgataatatc gaacaggttc atggcgaagg
    47581 cgatcagatt ggtatcgtca tcctgctctt caatgctttc tgccagtgcc tgggcttttt
    47641 cgccaccgtt ggaatggatc tccagcaggc ggtcacgccc ctgttccagt tgtgctttca
    47701 gcgcttcgtg ctgctcgcgg cagtttttga ttagatcgtc aaagccttcg gtctcatccg
    47761 gtgaagccag atagttaatc agatcgttgt atacgctatc gtaaatagtg cgtccggtcg
    47821 ggcaggtgtg ctcgaacgca tccagacctt cgtgatacca gcgcaccagc accgactgag
    47881 ccgttttttc cagataaggc acatggatct gaatatcgtg cgcctgaccg atacgatcca
    47941 gacgcccaat acgctgctcc agcagatccg ggttgaatgg caggtcaaac atcaccatgt
    48001 ggctggcgaa ctggaagtta cgtccttcag aaccgatttc cgagcacagc agtacctgcg
    48061 caccggtgtc ttcttcagca aaccaggcgg cagcgcggtc acgttcgata atcgacatgc
    48121 cttcgtggaa cactgcggcg cgaatacctt cacgttcgcg cagtacctgc tccagttgca
    48181 gcgcagtggc cgctttggcg cagatcacca gcactttctg agagcgatga ctggtcaggt
    48241 agcccatcag ccattcaacg cgcggatcga agttccacca ggtggcgtta tcgccttcaa
    48301 attcctgata aatacgctcc ggatagagca tatcgcgagc gcgatcttcc gcacttttgc
    48361 gtgcgcccat aatgccggag actttaatag cggtctgata ctgcgtcggc agtggcagct
    48421 taatagtatg cagctcgcgt ttcgggaagc ctttcacacc gttacgggtg ttacggaaca
    48481 gcacgcggct ggtaccgtgg cgatccatca gcatcgaaac cagttcctga cgggcgctct
    48541 gggcatcttc gctgtcgctg tttgctgctt gcaacagcgg ctcgatatcc tgctcgccga
    48601 tcatctcacc gagcatgttc agttcgtcat tgctgagttt gttacccgcc agcagcatgg
    48661 caacggcgtc cgcaaccgga cgataatttt tctgctcttc aacgaattgc gcaaaatcgt
    48721 ggaaacggtt cgggtccagc agacgcagac gggcgaagtg gctttccatc cccagctgtt
    48781 ccggggttgc ggtcagcagc agaacgcccg gcacgtgctc tgccagttgt tcaatggcct
    48841 gatattcacg gctcggcgca tcttcgctcc acaccaggtg atgcgcttca tcgaccacca
    48901 gtagatccca ctcggcttca cagagatgtt ccagacgctg tttgctacga cgggcaaaat
    48961 ccagcgagca aatcaccagc tgctcggtat cgaacgggtt gtaagcatcg tgctgagctt
    49021 cggcataacg ctcatcatca aacagagcaa agcgcaggtt gaaacggcgc agcatttcta
    49081 ccagccactg atgctgtaag gtttccggga cgataatcag cacacgttca gcagcgccag
    49141 agagcagttg ctgatgcagg atcatcccgg cctcaatggt tttccctaaa cccacttcgt
    49201 cagccaacag gacgcgcggc gcgtggcggc gaccaacatc atgagcgatg ttgagctggt
    49261 gcgggatcag gctggtacgc tgaccgcgca ggccgctgta cggcatacgg aactgttcgc
    49321 tggaatactt acgcgcgcga taacgcagcg caaagcggtc catacggtca atctgcccgg
    49381 caaacagacg gtcctgcggt ttgctgaaca ccagtttgct atcaaggaaa acttcacgca
    49441 gggccacgcc ggactcttca gtatcaaggc gagtaccgat ataggtcagc aagccatttt
    49501 cttcttttac ttcttcgact tgcatctgcc agccgtcatg gctggtaatg gtatcaccag
    49561 ggttgaacat cacgcgggtc acgggggaat cactgcgtgc gtacagacgg ttttcaccag
    49621 tagatgggaa aagtaaagtg acagttcgcg catccaccgc gacaacggtt ccaagtccca
    49681 attcgctttc tgtatcgctg atccagcgtt gaccaagtgt aaaaggcata tgtgttcggc
    49741 tctatatctt taattgcagg caataaccac ccgctaccgt gcttatgagg tagtggtgtt
    49801 attcaggtcc aggaatggaa agggcgctat ggtactggat ggcaaagcat tcgtcacgca
    49861 tcaaaatggt atctggcgaa ctcttttttt tgctcaaaat agcccaagtt gcccggtcat
    49921 aagtgtagca aaattatcct caataaaagg gagtattccc tccgctacgg gttgtagctg
    49981 gcgggtcaga tagtgttcgt aatccagtgg tgaacgttgg tagtccagcg gctccgggcc
    50041 gttggtggtc catacgtact taatggtgcc gcggttctga tattgcaagg ggcgaccgcg
    50101 cttatggttt tcttcatcgg caaggcgagc ggcgcgtaca tgaggcggca cattacgctg
    50161 atattcgctc agcggacggc gaaggcgttt acggtaaacc agccgcgcat ccagttcacc
    50221 cgccatcagt ttgtcgatgg tttcacgcac gtattcctga tatggctcgt tgcggaagat
    50281 acgcaggtaa agctcctgct gaaactgctg ggccagtggc gtccagtcgg tgcgcacggt
    50341 ttccagccct ttaaacacca tccgctgttt gtcgccctcc tgaatcagtc cggcgtagcg
    50401 ctttttgctg ccggtatcgg ccccgcgaat ggttggcatc agaaaacggc agaaatgggt
    50461 ttcatactcc agttccagtg cgctggtcag ccgttgtttt tgcagcgttt ccgcccacca
    50521 ggcgttaacg tgctgcacca gtgcacgacc gattttcgct gcttcttctt ccgaatgtgc
    50581 acctttcagc cagacaaacg ttgagtcggt atcgccgtag ataacgtcat agccctgcgc
    50641 ttcaatcaac gttttggttt gccgcatgat ctgatgacca cgcatggtga tcgacgatgc
    50701 caggcgtgga tcgaagaaac ggcaggcggt ggtgccgagc acaccataaa aggcattcat
    50761 aatgatcttc agcgcctgcg aaagcggctt attaccctga cgtttggctt catcgcgccc
    50821 gtgccagatg ttagtcacaa tctccggcag gcaatgtttc tcccgtgaga accacgcatc
    50881 gagaaaacct tcggtactgt gctctggatc aggctgcgcc atgccttcca ccagcccgac
    50941 gggatcaatc agaaaggtgc ggatgatcga cgggtacagg cttttgtagt ccagcaccag
    51001 caccgaatca taaagcccag gtcgcgaatc catcacgtag ccgccagggc tggcgtgcgg
    51061 cggcacttcg ccgagattag gcgcgacata accagcgcga tgcatacggg gaaaatagag
    51121 atgaccaaac gctgccaccg aaccgccgtg tcgatccacc ggcaggccgt tcaccgtcgc
    51181 ccgttcgagc aaaaacggca taatttcagt tttgtggaag atctgcgtca ccagctcgca
    51241 atctttcagg ttataagttg ccagcgcagg tttatcttcg gcgaaacggc ggtcaatttc
    51301 gtccattcga tcccacgggt tatcgataga ttttccttcg cctaataact cctgagcgac
    51361 ggtttccagc gagaatgaag agaaattcca gaacgcggat ttcagcgcct cgataccgtc
    51421 gataattagc cgacctttaa cctgagcaaa aaacacaccg tttttaaagc cgtgctcgcg
    51481 ccactccagc tcactgttat cacgccccag ccgcagcgga atacggtaac gctcggcatg
    51541 tttttgcagc attcgcagat cgaactgcac cacgttccaa ccgatgatca catcaggatc
    51601 gtagttggca aaccaggcgt taagtttttc cagtagcagc gggcggctgg cgacgtattc
    51661 cagttcaaaa tcgagcgcgg aggcgtcgcc attctctggc cccagcatat aaacgatacg
    51721 ctgcccgcaa ccttccaggc cgatgcagta cagctcaccg tggcgggtgg tttcaatatc
    51781 aatagaaacc cacttgagcg gcggacgata gtcgggatgc ggtttcagac gggcattaac
    51841 gatagcgcca ttgcgcatat caccctcgac ccacaccggt gaggtgataa atcgctccat
    51901 cagatagcgt tctggcgggc gcacatcggc ctcgtagacg gtaacgccac cttcacgcag
    51961 gcgcttttcg taattcatca actggcgatg ggcgcgacag taaaggccat acaccggctg
    52021 gcggtgaaaa tcttttaacg ccagcggcgt caggcgaaag ccttgttcac cctgcaaaat
    52081 atgctgagcg cggggaacct gatcggcagg aataaacgcc acggactctt gcggcgcaag
    52141 gaaaacctgc aacggcccgt tgtccgtcgc cagccagaag gaaacttcgg tcccttgcgg
    52201 ggtgtcccgc cagtgtcggg ttaagataaa acctgcctgc gccacgctga aaatccaata
    52261 aaaaaccagg cttgattata gcctggtttc gtttgattgg ctgtggtttt atacagtcat
    52321 tactgcccgt aatatgcctt cgcgccatgc ttacgcagat agtgtttatc cagcagcgtt
    52381 tgctgcatat ccggtaactg cggcgctaac tgacggcaga atatacccat ataagcgacc
    52441 tcttccagca cgatggcatt atgcaccgca tcttcggcat ttttgcccca tgcaaatggg
    52501 ccgtgagaat ggaccaggac gccgggcatt tgcgctgcat cgataccctg tttttcgaag
    52561 gtttctacga tgacgttacc ggtttcccac tcatattcac cgttgatttc tgcgtcggtc
    52621 attttgcggg tgcagggaat gggaccgtag aaatagtcgg cgtgggtggt accggttgcc
    52681 ggaattgact gacccgcctg cgcccagatg gtggcgtggc gcgagtgtgt gtgcacaatg
    52741 ccgccaatgg acgggaatgc ctgatagagc agccggtgag ttggcgtgtc ggaggagggc
    52801 tttttcgtac cttcaaccac ttcaccggtt tcgatgctga ccacgaccat atcgtcagcg
    52861 gtcatgatgc tgtagtcgac gccggaaggt ttgatcacaa agacgccgcg cccgcgatca
    52921 acggcgctga cgttgcccca ggtgagcgtg accaggttgt gttttggcag cgccaggttg
    52981 gcttctaata cctggcgttt gagatcttct aacatgttga ctccttcgtg ccggatgcga
    53041 tttgcttatc cggcctacaa aatcgcagcg tgtaggcctg ataagacgcg tcggcgtcgc
    53101 atcaggcgtt acatacctga tgcggctact tagcgacgaa atccgtaata cacttcgttc
    53161 cagcgcagcg cgtctttaaa cgctggaagg cgggtatcgt tatcaatcac cgtgatttca
    53221 atgtcgtgca tctcggcgaa ctggcgcata tcgttgaggt tcagcgcatg gctgaagacg
    53281 gtatggtgcg cgccaccggc aaggatccac gcttcggaag cggtcggcag atccggttgc
    53341 gctttccaca gcgcattcgc caccggcagt ttcggcaggg agtgcggtgt tttcaccgtg
    53401 tcgatgcagt taaccagcag acgataacga tcgccgagat caatcaggct ggcgacaatg
    53461 gccggaccag tttgagtatt gaagatcagg cgagccgggt cgtctttacc gccaatacca
    53521 aggtgctgaa cgtcgaggat cggtttctct tccacagcga tcgacgggca gacttccagc
    53581 atatgggagc cgagtaccag gtcattacct ttctcgaagt gataggtgta gtcctccata
    53641 aaggaggtgc cgccctgcag accggttgac atcaccttca tgatgcgaag cagggcggca
    53701 gttttccagt cgccttcgcc cgcaaagccg tagccctgct gcatcagacg ctgtacggcc
    53761 agaccaggaa gctgtttcag gccgtgcaaa tcttcaaagg tagtagtgaa agcgtggaag
    53821 ccaccctgtt ccaggaaacg cttcatcccc agctcaatac gcgccgcttc cagcacgttc
    53881 tgtcgttttt cgccgtggat ttgtgtggca ggtgtcatgg tgtagcagct ttcgtactca
    53941 tcgaccagcg cgttaacatc gccgtcgctg atggagttca ccacctgcac cagatcgcca
    54001 accgcccagg tattgacgga gaaaccaaac ttgatctgtg cggcaacttt atcgccatcg
    54061 gtgaccgcta cttcacgcat gttatcgcca aaacggcaga ctttcagatg acgggtatcc
    54121 tgtttagaga ccgcctgacg catccaggag ccgatacgct catgtgcttg tttatcctgc
    54181 cagtgaccgg taacaacggc atgttgctga cgcatacgcg cgccgatgaa gccgaactcg
    54241 cgaccgccat gcgcggtctg gttcaggttc ataaagtcca tgtcgatgct gtcccacggc
    54301 agcgccgcgt tgaactgggt gtggaattgc agcaacggtt tgttgagcat ggtcaggccg
    54361 ttgatccaca ttttggccgg ggagaaagtg tgcagccaca ccaccagacc agcgcaacga
    54421 tcgtcgtaat tcgcgtcgcg gcaaatagcg gtgatttcat ccggcgtggt gcccagcggt
    54481 ttcagcacca gtttgcaggg caacttcgct tctgtattca gtgcattaac aacgtgttcc
    54541 gcatgttgcg tcacctggcg cagagtctcc gggccgtaaa gatgctggct gccaattaca
    54601 aaccacactt cataattatc aaaaatcgtc attgtcgtgt ccttatagag tcggaacggc
    54661 ctgggcagcc tgtgccgggg cggaagttgg aagatagtgt tgttcggcgc tcatcgccca
    54721 ttgctgatag cggcgataaa gctgttcaaa gcgttgtgcc tgttcgctgc gcggttgcag
    54781 ggttttctct accgcactgg ccattttttg ctgggctgat gggatgtctg cgtgcacttt
    54841 cgcggcgaca gcagcaaaaa tcgccgcacc gagcgcacag cactggtcag aggcaacaat
    54901 ttgcagcggg cgattcagca cgtcgcagca ggcctgcata atgacctggt ttttccgcgc
    54961 gatgccgccc agcgccatca cgttattgac ggcgatcccc tgatcggtaa agcactccat
    55021 gattgcgcgt gcgccaaagg cggtggcagc aatcaaaccg ccgaacagca gcggagcgtc
    55081 ggtagcgagg ttcagatcgg taatcacccc tttcaggcgt tggttagcgt tcggtgtgcg
    55141 gcggccgtta aaccagtcga gcaccaccgg taggtgatcc agagacggat tttgagccca
    55201 tacttcggtc agcgccggaa gcagttgttt ctggctggcg ttgatttgct ctttcagttc
    55261 cggatgctgg gcggcaagct gttccagcgg ccagccgagt acgcgaccaa accaggcgta
    55321 gatatcccca aacgccgatt ggcctgcttc cagaccgata aatccaggca ccacgctgcc
    55381 atcaacctga ccgcaaatac ctttcactgc ccgctcgcca acgctctgtt tgtcggcaat
    55441 cagaatgtca caggtggaag taccgataac ttttaccagt gcgttaggct gtgcgcctgc
    55501 gccaactgcg cccatatggc agtcaaacgc gccgccggaa atcactacgc tttcaggcag
    55561 gccgagacgc tgcgcccatt ccgggcataa ggtgcccacc ggaatatcgg cagtccaggt
    55621 atcagtgaac agcggggaag gcaaatggcg attgaggatc gggtccagct catcaaagaa
    55681 actggctggc ggcaggccac cccagctttc gtgccacaga gatttatgcc cggcgctgca
    55741 acgtccgcga cgaatatcct gcgggcgggt ggtaccggaa agcagagctg gcacccagtc
    55801 gcacagctca atccatgatg cggcagattg tgccacggcg ttgtcctggc gagttacatg
    55861 caggattttt gcccagaacc attcgctgga ataaataccg ccaatattgc gggagtagtc
    55921 aacgttgccc ggcgtgtgac ataagcgggt aatctcttcc gcttcttcaa ccgcggtgtg
    55981 gtctttccac aatacgaaca tcgcgttcgg gttctcggca aactccgggc gcagcgccaa
    56041 cacgttgccg tcggcgtcaa tcggtgcggg cgtcgagccg gttgtgtcaa cgccaatccc
    56101 gaccacagct gcgcgctgtt cgacgcaaag ctctgcaagc acagttttca gcgccgcttc
    56161 cattgactca atgtagtcac gcggatgatg acggaactgg ttattcgggg catcacaaaa
    56221 ttgcccgttc tgccaacggg gataccactc tacgctggtg gcgatctctt caccagtggc
    56281 gcattccacc gccaaagctc gcacagaatc actgccaaaa tcgaggccaa ttgcaatcgc
    56341 catcgtttca ctccatccaa aaaaacgggt atggagaaac agtagagagt tgcgaaaaaa
    56401 aacgtcaggc tggatccgct aatcttatgg ataaaaatgc tatggcatag caaagtgtga
    56461 cgccgtgcaa ataatcaatg tggacttttc tgccgtgatt atagacactt ttattacgcg
    56521 tttttgtcat ggctttggtc ccgctttgtt acagaatgct tttaataagc ggggttaccg
    56581 gttgggtcag cgagaagagc cagtaaaaga cgcagtgacg gcaatgtctg atgcaatatg
    56641 gacaattggt ttcttctctg aatggcggga gtatgaaaag tatggctgaa gcgcaaaatg
    56701 atcccctgct gccgggatac tcgtttaacg cccatctggt ggcgggttta acgccgattg
    56761 aggccaacgg ttatctcgat ttttttatcg accgaccgct gggaatgaaa ggttatattc
    56821 tcaatctcac cattcgcggt cagggcatag tgaaaaacca gggacgagaa tttgtctgcc
    56881 gaccgggtga tattttgctg ttcccgccag gagagattca tcactacggt cgtcatccgg
    56941 aggctcacga atggtatcac cagtgggttt actttcgtcc gcgcgcctac tggcatgaat
    57001 gggttaactg gccgtcgata tttgccaata ccggtttctt tcgcccggat gaagcgcacc
    57061 agccgcattt cagcgacctg tttgggcaaa tcattaatgc cggacaaggg gaagggcgct
    57121 attcggaatt gctggcgata aatctgcttg agcaattgtt actgcggcgc atggaagcga
    57181 ttaacgagtc gctccatccg ccgatggata atcgggtacg cgaggcttgt cagtacatca
    57241 gcgatcacct ggcagacagt aattttgata tcgccagcgt cgcacagcat gtctgcctgt
    57301 cgccgtcgcg tctgtcgcat ttgttccgcc agcagttagg gattagcgta ttaagctggc
    57361 gcgaggacca gcgcatcagt caggcgaagc tgcttttgag caccacccgg atgcctatcg
    57421 ccacagtcgg tcgcaatgtc ggttttgacg atcaactcta tttctcgcga gtatttaaaa
    57481 aatgcaccgg ggccagcccg agcgagttta gggctggatg tgaataataa g
//
LOCUS       DAFGPF010000017        57424 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFGPF010000017 DAFGPF010000000
VERSION     DAFGPF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57424
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.017"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            221..847
                     /locus_tag="LSX49_001244"
     CDS             221..847
                     /locus_tag="LSX49_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HBL7167680.1"
                     /translation="MNPVDRPLLNIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKESQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
     gene            868..2970
                     /locus_tag="LSX49_001245"
     CDS             868..2970
                     /locus_tag="LSX49_001245"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HBL7167681.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPP
                     GNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFKAITGEDMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQR
                     LGLEDIAADLAAHNLLPA"
     gene            2983..3621
                     /locus_tag="LSX49_001246"
     CDS             2983..3621
                     /locus_tag="LSX49_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310406.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HBL7167682.1"
                     /translation="MNHQDELPLAKVSEIDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLENIKQNGDYADIACMTGSQDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            3685..4353
                     /locus_tag="LSX49_001247"
     CDS             3685..4353
                     /locus_tag="LSX49_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBL7167683.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVIDNDNGTQYHFFRQSCQHCEDAPCID
                     VCPTGASWRDEQGIVRVEKSQCIGCSYCIGVCPYQVRYLNPVTKVADKCDFCAETRLA
                     KGFPPICVSACPEHALIFGHEDSPEIQAWLQENKYYQYQLPGAGKPHLYRRFGQHLIK
                     KENV"
     gene            4350..5135
                     /locus_tag="LSX49_001248"
     CDS             4350..5135
                     /locus_tag="LSX49_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HBL7167684.1"
                     /translation="MNPSQHAEQFQSQLANYVPQFTPQFWPVWLIIAGLLLVGMWLVL
                     GLHALLRARGVKKSATDHSERIYLYSKAVRLWHWSNALLFVLLLASGLINHFALVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLDRAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYW
                     LLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            5139..5951
                     /locus_tag="LSX49_001249"
     CDS             5139..5951
                     /locus_tag="LSX49_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167685.1"
                     /translation="MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERLFCSQFVRSDDHARLGCCED
                     NARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGARARVAVTGNSSRISSAGDSGRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGCAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC"
     gene            complement(5963..7567)
                     /locus_tag="LSX49_001250"
     CDS             complement(5963..7567)
                     /locus_tag="LSX49_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HBL7167686.1"
                     /translation="MKTIAIVGAGPTGIYTLFSLLQQQTPLSISIFDQADEAGIGMPY
                     SDEENSKLMLANIASIEIPPIYCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILL
                     GEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNLNLPSETFDLAVI
                     ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFI
                     EDDKQHVTFHRDNANEKLNITLMSRTGILPEADFYCPIPYEPLHIITDQALNAEIQKG
                     EVGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEENL
                     QEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPS
                     ESIRRLLALREAGIIHILALGEDYEMEINESRTVLKTEDNSYSFDVFIDARGQRPLKV
                     KDIPFPGLREQLQKTGDEIPNVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGITA
                     CAEIGEAMARAVVKPASRARRRLSFD"
     gene            complement(7693..7998)
                     /locus_tag="LSX49_001251"
     CDS             complement(7693..7998)
                     /locus_tag="LSX49_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBL7167687.1"
                     /translation="MATLLQLHFSFNGPFGDTMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNVPLSQINQAKLA"
     gene            complement(8107..8183)
                     /locus_tag="LSX49_001252"
     tRNA            complement(8107..8183)
                     /locus_tag="LSX49_001252"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8147..8149),aa:Val,seq:gac)
     gene            complement(8188..8264)
                     /locus_tag="LSX49_001253"
     tRNA            complement(8188..8264)
                     /locus_tag="LSX49_001253"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8228..8230),aa:Val,seq:gac)
     gene            8572..9828
                     /locus_tag="LSX49_001254"
     CDS             8572..9828
                     /locus_tag="LSX49_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HBL7167688.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRH
                     PEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEACNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGAIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFGIGNINL
                     NGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            complement(9869..11242)
                     /gene="mdtK"
                     /locus_tag="LSX49_001255"
     CDS             complement(9869..11242)
                     /gene="mdtK"
                     /locus_tag="LSX49_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HBL7167689.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAI
                     ILQRAAR"
     gene            11457..12098
                     /gene="ribE"
                     /locus_tag="LSX49_001256"
     CDS             11457..12098
                     /gene="ribE"
                     /locus_tag="LSX49_001256"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBL7167690.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(12138..13286)
                     /gene="cfa"
                     /locus_tag="LSX49_001257"
     CDS             complement(12138..13286)
                     /gene="cfa"
                     /locus_tag="LSX49_001257"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HBL7167691.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(13577..14788)
                     /locus_tag="LSX49_001258"
     CDS             complement(13577..14788)
                     /locus_tag="LSX49_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HBL7167692.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKPVLFIGLTIFALGSLGMLWVENAATLLILRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNH
                     GNAEVAHSESH"
     gene            14901..15833
                     /locus_tag="LSX49_001259"
     CDS             14901..15833
                     /locus_tag="LSX49_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7167693.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     LVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALKLENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(15830..16855)
                     /gene="purR"
                     /locus_tag="LSX49_001260"
     CDS             complement(15830..16855)
                     /gene="purR"
                     /locus_tag="LSX49_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HBL7167694.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            17154..17243
                     /gene="ynhF"
                     /locus_tag="LSX49_001261"
     CDS             17154..17243
                     /gene="ynhF"
                     /locus_tag="LSX49_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein YnhF"
                     /protein_id="HBL7167695.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            17409..18578
                     /locus_tag="LSX49_001262"
     CDS             17409..18578
                     /locus_tag="LSX49_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7167696.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFLSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHVTPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAIVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPEAVCVANS"
     gene            complement(18724..19305)
                     /gene="sodB"
                     /locus_tag="LSX49_001263"
     CDS             complement(18724..19305)
                     /gene="sodB"
                     /locus_tag="LSX49_001263"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HBL7167697.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKPLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(19433..20260)
                     /gene="mepH"
                     /locus_tag="LSX49_001264"
     CDS             complement(19433..20260)
                     /gene="mepH"
                     /locus_tag="LSX49_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-endopeptidase MepH"
                     /protein_id="HBL7167698.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTQKTQKASQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNK
                     TASASFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPY
                     RWGGSSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFF
                     RTQGRGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            20595..20942
                     /gene="grxD"
                     /locus_tag="LSX49_001265"
     CDS             20595..20942
                     /gene="grxD"
                     /locus_tag="LSX49_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HBL7167699.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(20993..21085)
                     /locus_tag="LSX49_001266"
     CDS             complement(20993..21085)
                     /locus_tag="LSX49_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001441976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL7167700.1"
                     /translation="MNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(21314..21961)
                     /gene="rnt"
                     /locus_tag="LSX49_001267"
     CDS             complement(21314..21961)
                     /gene="rnt"
                     /locus_tag="LSX49_001267"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HBL7167701.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAAEV"
     gene            complement(22064..22471)
                     /gene="gloA"
                     /locus_tag="LSX49_001268"
     CDS             complement(22064..22471)
                     /gene="gloA"
                     /locus_tag="LSX49_001268"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBL7167702.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTNVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(22552..23649)
                     /gene="nemA"
                     /locus_tag="LSX49_001269"
     CDS             complement(22552..23649)
                     /gene="nemA"
                     /locus_tag="LSX49_001269"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HBL7167703.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRISPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(23686..24285)
                     /gene="nemR"
                     /locus_tag="LSX49_001270"
     CDS             complement(23686..24285)
                     /gene="nemR"
                     /locus_tag="LSX49_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416166.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NemR"
                     /protein_id="HBL7167704.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV"
     gene            24388..24627
                     /locus_tag="LSX49_001271"
     CDS             24388..24627
                     /locus_tag="LSX49_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HBL7167705.1"
                     /translation="MTEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            24676..25572
                     /locus_tag="LSX49_001272"
     CDS             24676..25572
                     /locus_tag="LSX49_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HBL7167706.1"
                     /translation="MVQRITIAPQGPEFSHFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTACEENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            25653..26174
                     /gene="sodC"
                     /locus_tag="LSX49_001273"
     CDS             25653..26174
                     /gene="sodC"
                     /locus_tag="LSX49_001273"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HBL7167707.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEVKDKALIVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(26175..28187)
                     /locus_tag="LSX49_001274"
     CDS             complement(26175..28187)
                     /locus_tag="LSX49_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL7167708.1"
                     /translation="MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWRPETTDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPDATREIL
                     EQLLTALASSQTDVYTVARIISPLRPTNVTDYRHIAFWQRLRYFCRLYLQSSQELHRL
                     QSGVDDHARLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(28187..29044)
                     /locus_tag="LSX49_001275"
     CDS             complement(28187..29044)
                     /locus_tag="LSX49_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416161.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBL7167709.1"
                     /translation="MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQ
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LQGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFTLDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(29047..29283)
                     /locus_tag="LSX49_001276"
     CDS             complement(29047..29283)
                     /locus_tag="LSX49_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HBL7167710.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVIHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            29484..29918
                     /gene="slyA"
                     /locus_tag="LSX49_001277"
     CDS             29484..29918
                     /gene="slyA"
                     /locus_tag="LSX49_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HBL7167711.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG"
     gene            complement(29965..30432)
                     /gene="slyB"
                     /locus_tag="LSX49_001278"
     CDS             complement(29965..30432)
                     /gene="slyB"
                     /locus_tag="LSX49_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HBL7167712.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRQVQIQGGDDSNVIGAIGGAVLGGFLGNTIGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTHFSPGQRVVLASNGSQVTVSPR"
     gene            30706..31815
                     /gene="anmK"
                     /locus_tag="LSX49_001279"
     CDS             30706..31815
                     /gene="anmK"
                     /locus_tag="LSX49_001279"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBL7167713.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATVAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP"
     gene            31913..32242
                     /gene="mliC"
                     /locus_tag="LSX49_001280"
     CDS             31913..32242
                     /gene="mliC"
                     /locus_tag="LSX49_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HBL7167714.1"
                     /translation="MSMKKLLLICLPVLLTGCSAFNQLVERMQTDTLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGEEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            32301..32957
                     /gene="pdxH"
                     /locus_tag="LSX49_001281"
     CDS             32301..32957
                     /gene="pdxH"
                     /locus_tag="LSX49_001281"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HBL7167715.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACE
                     AKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            33086..34360
                     /gene="tyrS"
                     /locus_tag="LSX49_001282"
     CDS             33086..34360
                     /gene="tyrS"
                     /locus_tag="LSX49_001282"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBL7167716.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            34422..35282
                     /gene="pdxY"
                     /locus_tag="LSX49_001283"
     CDS             34422..35282
                     /gene="pdxY"
                     /locus_tag="LSX49_001283"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310372.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase PdxY"
                     /protein_id="HBL7167717.1"
                     /translation="MKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHT
                     QYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAA
                     NPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHPVNNV
                     EEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQP
                     VGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIAN
                     PEHYFSATKL"
     gene            complement(35326..35931)
                     /gene="gstA"
                     /locus_tag="LSX49_001284"
     CDS             complement(35326..35931)
                     /gene="gstA"
                     /locus_tag="LSX49_001284"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HBL7167718.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(36037..37539)
                     /gene="dtpA"
                     /locus_tag="LSX49_001285"
     CDS             complement(36037..37539)
                     /gene="dtpA"
                     /locus_tag="LSX49_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HBL7167719.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHTILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAVIAVLMLFTAPKLHRMTQDDAADKAAKAAVA"
     gene            complement(38150..38785)
                     /gene="nth"
                     /locus_tag="LSX49_001286"
     CDS             complement(38150..38785)
                     /gene="nth"
                     /locus_tag="LSX49_001286"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBL7167720.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAYGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(38785..39480)
                     /gene="rsxE"
                     /locus_tag="LSX49_001287"
     CDS             complement(38785..39480)
                     /gene="rsxE"
                     /locus_tag="LSX49_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxE"
                     /protein_id="HBL7167721.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDEKMKKRRTEAA
                     AERALPNGETGNV"
     gene            complement(39484..40104)
                     /gene="rsxG"
                     /locus_tag="LSX49_001288"
     CDS             complement(39484..40104)
                     /gene="rsxG"
                     /locus_tag="LSX49_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HBL7167722.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDANWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE"
     gene            complement(40108..41166)
                     /gene="rsxD"
                     /locus_tag="LSX49_001289"
     CDS             complement(40108..41166)
                     /gene="rsxD"
                     /locus_tag="LSX49_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HBL7167723.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMMLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTTSGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEEIMQYPIYSGILAGA
                     GWQWVNLAWLTGGVWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPDTLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(41167..43587)
                     /gene="rsxC"
                     /locus_tag="LSX49_001290"
     CDS             complement(41167..43587)
                     /gene="rsxC"
                     /locus_tag="LSX49_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBL7167724.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWADYRSRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSHDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKTARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEQQVDPRKAAVE
                     AAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQQANAEPEEQVD
                     PRKAAVEAAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQQANA
                     EPEEQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQIDPRKAAVAAAIARVQAKKAA
                     QQKVVNED"
     gene            complement(43580..44158)
                     /gene="rsxB"
                     /locus_tag="LSX49_001291"
     CDS             complement(43580..44158)
                     /gene="rsxB"
                     /locus_tag="LSX49_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HBL7167725.1"
                     /translation="MNAIWIAVAAVSLLALAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     LTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            complement(44158..44739)
                     /gene="rsxA"
                     /locus_tag="LSX49_001292"
     CDS             complement(44158..44739)
                     /gene="rsxA"
                     /locus_tag="LSX49_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBL7167726.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(44816..45256)
                     /locus_tag="LSX49_001293"
     CDS             complement(44816..45256)
                     /locus_tag="LSX49_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707526.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HBL7167727.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            complement(45342..45557)
                     /gene="ydgT"
                     /locus_tag="LSX49_001294"
     CDS             complement(45342..45557)
                     /gene="ydgT"
                     /locus_tag="LSX49_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HBL7167728.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
     gene            complement(45829..45954)
                     /gene="blr"
                     /locus_tag="LSX49_001295"
     CDS             complement(45829..45954)
                     /gene="blr"
                     /locus_tag="LSX49_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HBL7167729.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSTTVQHK"
     gene            46206..47015
                     /locus_tag="LSX49_001296"
                     /pseudo
     CDS             46206..47015
                     /locus_tag="LSX49_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
     gene            complement(47051..48052)
                     /gene="add"
                     /locus_tag="LSX49_001297"
     CDS             complement(47051..48052)
                     /gene="add"
                     /locus_tag="LSX49_001297"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBL7167730.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLT
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(48156..49328)
                     /gene="malY"
                     /locus_tag="LSX49_001298"
     CDS             complement(48156..49328)
                     /gene="malY"
                     /locus_tag="LSX49_001298"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000459377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HBL7167731.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLIHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDPQSVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRVYLKDNLTYIADKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKIAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVG"
     gene            complement(49338..50930)
                     /gene="malX"
                     /locus_tag="LSX49_001299"
     CDS             complement(49338..50930)
                     /gene="malX"
                     /locus_tag="LSX49_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HBL7167732.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     VGYAVMNLAVNFWLTNKGILPTMDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYIIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMVGLMRTVQA"
     gene            51105..52133
                     /gene="malI"
                     /locus_tag="LSX49_001300"
     CDS             51105..52133
                     /gene="malI"
                     /locus_tag="LSX49_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mal regulon transcriptional regulator MalI"
                     /protein_id="HBL7167733.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRIAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVIWASTPARELGTTLADRMMQKITHEETHSRNLII
                     PARLIAAK"
     gene            52245..53012
                     /gene="hdhA"
                     /locus_tag="LSX49_001301"
     CDS             52245..53012
                     /gene="hdhA"
                     /locus_tag="LSX49_001301"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HBL7167734.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAVSKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLIAPEMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTNALKSVITPEIEQKMLQHTPIRRL
                     GQPQDIANAALFLCSPAASWVSGQILTVSGDGVQELN"
     gene            53241..53831
                     /gene="uidR"
                     /locus_tag="LSX49_001302"
     CDS             53241..53831
                     /gene="uidR"
                     /locus_tag="LSX49_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator UidR"
                     /protein_id="HBL7167735.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            54221..56032
                     /gene="uidA"
                     /locus_tag="LSX49_001303"
     CDS             54221..56032
                     /gene="uidA"
                     /locus_tag="LSX49_001303"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBL7167736.1"
                     /translation="MLRPVETPTREIKKLDGLWAFSLDRENCGIDQHWWESALQESRA
                     IAVPGSFNDQFADADIRNYVGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQ
                     EVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSY
                     FHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRD
                     ADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYLLRVGIRSVAV
                     KGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYA
                     EEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAI
                     KELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCD
                     AHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVD
                     TLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGN
                     KKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ"
     gene            56029..57401
                     /gene="uidB"
                     /locus_tag="LSX49_001304"
                     /pseudo
     CDS             56029..57401
                     /gene="uidB"
                     /locus_tag="LSX49_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416133.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide transporter"
BASE COUNT        14570 a        13995 c        14910 g        13949 t
ORIGIN      
        1 tttaattgat aacgatcaat gttaagagcc cagaataatc acattatttt ttctcctaac
       61 cataaaggat tagtttgtta gcgttaaatc ttttctcata cactatcggg ttagggaaaa
      121 tatctggtgt tgaggacagc gtcagcagcg tattagttga gtgcttaata tcaggctgtt
      181 gaattgtcag cactgtgttt gcgaagagga tgcgaaataa atgaacccgg ttgatcgtcc
      241 actattaaat attggcttaa cgcgattaga attcttgcgt atatcaggaa aaggccttgc
      301 tggtttaaca attgcccctg ctttactgtc acttttgggt tgcaaacagg aagatattga
      361 tagcggcaca gtagggttga taaatacacc caaaggggtg ctggtgaccc aacgtgcgcg
      421 atgcacgggt tgccaccgct gtgaaatctc ttgtaccaac ttcaacgatg gctcagtagg
      481 gacattcttc tcccgtatca aaatccatcg caattatttc tttggcgaca acggggttgg
      541 ctctggcggt ggcctgtatg gcgatctcaa ctataccgcg gatacctgcc gtcaatgcaa
      601 agagtcgcaa tgcatgaacg tctgcccgat tggtgcgatt acctggcagc agaaagaagg
      661 ctgtattacc gtcgatcata aacgttgtat tggctgtagc gcctgtacta cggcatgccc
      721 gtggatgatg gccaccgtaa ataccgaaag taaaaaatcc tcgaaatgtg tgttatgcgg
      781 tgaatgcgca aacgcctgcc caacaggggc gttaaaaatt atcgagtgga aagatattac
      841 tgtgtgaatc ttgcaaagga aaaaatcatg gctaacggtt ggacaggtaa tatattaaga
      901 gtcaatctca cgacaggaaa tattaccctc gaagattcca gtaaatttaa aagttttgtc
      961 ggtggcatgg gcttcggcta caaaattatg tatgacgaag taccgccagg cacgaaacct
     1021 ttcgatgaag cgaataaatt agtttttgct accggcccat taactggatc tggtgccccc
     1081 tgtagttctc gcgtaaatat cacctcactt tctactttta ccaaaggaaa tttagtcgtc
     1141 gatgcccata tggggggctt ttttgcagcg caaatgaaat tcgctggata cgacgtcatt
     1201 attatcgaag ggaaagcgaa atcaccggta tggctgaaga ttaaagatga caaagttagc
     1261 cttgaaaaag ccgatttctt atggggaaaa gggacgcgcg caacgacgga agaaatttgt
     1321 cgcttgacca gtccggaaac ctgtgtggcg gctattggtc aggctggaga aaaccttgtt
     1381 cctctctctg gcatgttgaa tagccgtaac cacagcggcg gtgcgggaac tggcgcaata
     1441 atgggttcga aaaacctgaa agcgattgcg gttgaaggga cgaaaggggt caacattgcc
     1501 gatcgtcagg agatgaagcg tctcaacgat tacatgatga ctgaacttat cggtgcgaat
     1561 aacaaccatg tcgtgccaag tacgccgcaa tcgtgggcag agtattcaga tcccaagtca
     1621 cgttggacag cacgtaaagg gctgttttgg ggcgcggctg aaggtggtcc gattgaaacg
     1681 ggggaaattc cgccaggcaa tcagaatacg gtcggctttc gtacctataa atccgttttt
     1741 gacttaggtc cggcggcaga gaaatacaca gtaaaaatga gtggctgcca ctcttgcccg
     1801 atccgttgta tgacccaaat gaatattcct cgggtgaaag agtttggcgt gcccagcaca
     1861 ggtggtaaca cttgtgtagc aaactttgtc cataccacca tcttcccgaa cgggccgaaa
     1921 gattttgaag ataaggacga tggtcgtgtg attggtaacc tggttggtct gaatttgttc
     1981 gatgactacg gcctatggtg taactacggg cagttgcatc gcgactttac ttattgttac
     2041 agcaaaggtg tgttcaagcg tgttctgcct gctgaagagt atgcggaaat tcgctgggat
     2101 caactggaag cgggtgacgt taactttatt aaagattttt actaccgtct ggcgcatcgc
     2161 gtgggtgagt tgagtcacct ggctgatggt tcatatgcca tcgcagaacg ctggaatttg
     2221 ggtgaagagt actggggcta cgcgaaaaat aaactctggt cgccgtttgg ctatccggtt
     2281 caccatgcca atgaagcgtc agcgcaagtc ggttccattg ttaactgtat gttcaaccgt
     2341 gactgcatga cgcataccca tatcaatttt attggttccg gcttgccatt gaaactgcag
     2401 cgtgaagtgg cgaaagagct ttttggttct gaagatgctt acgatgaaac caaaaactac
     2461 acaccgatca atgacgcaaa aattaaatat gctaagtggt cgctgttgcg ggtctgtttg
     2521 cataacgccg tcaccctgtg caactgggtc tggccaatga ccgtttcgcc gctgaaaagc
     2581 cgtaattacc ggggtgatct ggcgcttgaa gccaaattct tcaaagcgat cactggcgaa
     2641 gatatgactc aggaaaaatt agatttagct gcagagcgta tctttacgtt gcatcgcgcc
     2701 tacacggtaa aactgatgca aaccaaagat atgcgtaatg aacacgatct tatctgttcc
     2761 tgggtattcg acaaggatcc gcagatcccg gtctttactg aaggtacaga caaaatggac
     2821 cgtgacgata tgcatgcttc gctcacgatg ttctacaaag aaatgggctg ggacccacag
     2881 cttggttgtc cgacccgcga aacattgcag cgtctggggc tggaagatat tgccgccgat
     2941 ctggcagcac acaatctact gcctgcgtaa ggaatgggag agatgaacca tcaggatgaa
     3001 ttgccgttag cgaaagtcag cgaaattgat gaggcgaagc ggcaatggtt gcaggggatg
     3061 cgtcaccccg ttgatacggt aaccgaacca gaaccggctg aaatcctggc agagttcatt
     3121 cgccagcatt ctgcggctgg gcagctggtg gcgcgcgccg tgtttctctc gccaccctat
     3181 tcggttgcag aagaggaact gtcagttttg ctggaaaaca ttaagcagaa cggagactac
     3241 gcggatatcg cttgtatgac gggaagccag gatgattact attactcaac gcaggccatg
     3301 agtgaaaact acgcggcgat gtctttgcaa gttgtggagc aggacatttg tcgcgccatt
     3361 gcacacgccg ttcgttttga gtgccagacg tatcctcgtc cttacaaagt cgccatgctg
     3421 atgcaagcgc catattactt ccaggaagcg cagattgaag ccgcgatcgc cgcgatggat
     3481 gttgcacctg aatatgccga tatacggcag gtggagtcat cgacggcagt gttgtacttg
     3541 tttagcgagc gatttatgac ctatggcaag gcgtatggct tatgcgaatg gttcgaggta
     3601 gagcagtttc agaacccctg aaatttcagg gggatgtcat ggatagggtg gacagttgca
     3661 gccactgcat taggggataa tcagatgtcc ttcactcgac gcaaatttgt tctggggatg
     3721 ggaacagtaa tcttttttac tggttctgcg tcttctctgt tagcgaatac gaggcaagaa
     3781 aaggaagttc ggtatgccat gattcatgac gagtcacggt gcaatggctg taatatctgc
     3841 gcccgcgcat gccgtaaaac taaccacgtc cccgctcagg gaagccgttt atcgatagca
     3901 cacattccag tcatcgataa cgacaatgga acgcagtatc acttttttcg tcagtcatgt
     3961 cagcactgcg aagatgctcc ttgcatcgac gtttgcccga caggggcgtc gtggcgtgat
     4021 gagcagggga tcgtgcgggt agaaaaatcg cagtgcatcg gctgcagtta ttgcattggc
     4081 gtttgcccgt accaggttcg ctaccttaac cctgtcacta aagtggcaga taaatgtgat
     4141 ttctgcgctg agacccgact ggcaaaaggc tttccgccca tttgcgtcag tgcctgcccg
     4201 gaacacgcat tgatctttgg tcacgaagat agcccagaaa ttcaggcgtg gttgcaggaa
     4261 aataaatact atcaatatca gctacctggc gccgggaaac cgcatctgta tcgccggttc
     4321 ggtcaacatt tgattaaaaa ggaaaatgta tgaacccgtc gcaacatgct gaacagtttc
     4381 agagccagtt ggcgaactat gtgccacagt tcacccccca attttggccg gtgtggttga
     4441 tcattgccgg actattgctg gttgggatgt ggttggtgct ggggctacat gccttgcttc
     4501 gtgctcgtgg cgtgaagaaa tcagccaccg atcatagtga gaggatttat ctttacagca
     4561 aagcggtcag attatggcac tggtcgaatg cgttactctt tgtattgttg ctggcaagtg
     4621 ggctgataaa tcactttgcg ctggtgggcg caactgcggt taaaagtctg gttgcggtgc
     4681 atgaagtttg cggatttttg ttactggcat gctggcttgg ctttgttctg atcaatgccg
     4741 ttgggggtaa tggtcaccac tatcgcattc gtcgtcaggg ttggctggat cgagcggcaa
     4801 aacaaacgcg attttatttg tttggcatta tgcaggggga agaacatcct ttcccggcaa
     4861 caacccagtc taaatttaat cccttacagc aggtcgccta tgttggtgtc atgtatggat
     4921 tgttgccatt gttactattg acggggctgc tgtgtctcta tccgcaagcc gtgggagatg
     4981 tgtttcctgg cgtaagatac tggttattgc aggcgcattt tgctctggca tttataagcc
     5041 tcttttttat cttcggtcat ctttatcttt gcaccacggg gcgtacgcca cacgaaacct
     5101 ttaaaagcat ggtcgatggc tatcaccggc actaacgaat gatcattaca cgagcagacc
     5161 tgcgagaatg gcgtatcgga gcggtgatgt atcgctggtt tctgcgccat ttcccacgtg
     5221 gcggtagtta tgccgatatt catcatgcac tgattgagga aggatatacg gactgggcgg
     5281 agagtctggt tgagtatgcg tggaaaaaat ggctggcaga tgaaaacttc gcgcatcagg
     5341 aagtttcctc tatgcaaaaa ctggccacag atcccggaga acgactattt tgcagtcagt
     5401 ttgtccgcag cgacgatcat gctcgcctcg gctgttgtga ggataacgcc agaatcgcaa
     5461 ccgctgggta tgccgcgcaa attgccagta tgggttatag cgtgcggatt ggaagtgtcg
     5521 gctttaacag tcacattggc agctccggtg cacgcgcacg ggttgctgta accggtaatt
     5581 cttcgcggat aagcagcgct ggagatagcg gtcggattgc gaataccgga atgcgagtac
     5641 gcgtttgtac attgggtgaa cggtgtcatg tcgccagtaa tggtgacctg gtgcaaatcg
     5701 ccagctttgg cgcaaacgcc agaattgcca acagcggcga caatgtacac atcattgcca
     5761 gtggtgaaaa ttcaacggta gtgagcacgg gcgtggtcga ctcaattatt ctcgggccag
     5821 ggggatgcgc cgcactggca tatcatgacg gcgaaagagt tcgcttcgcc gtcgccattg
     5881 aaggtgaaaa caatattcga gccggagtcc gctatcgtct taatgaacaa catcagtttg
     5941 ttgagtgctg atagctttac ctttaatcaa acgaaagacg ccgacgcgca cgggatgcag
     6001 gttttacgac cgcccgagcc atcgcctctc caatttctgc acatgccgta attccctgaa
     6061 cgaaaggctg gtcgtgcatc aaccagggca acgcgccgaa cgctacgcgc ccacgaatat
     6121 cttcgggttg ctgtaacgta taatcttcgc caacattagg gatttcatcc cctgttttct
     6181 gtaattgttc gcgtagtcca gggaaaggaa tatctttcac tttaagcgga cgctgcccgc
     6241 gggcatcaat aaaaacgtca aacgagtagc tattgtcttc cgttttcagg acggtgcgcg
     6301 actcattaat ttccatttcg tagtcttcac cgagggcgag aatatgaatg attcccgctt
     6361 cacgtaaggc cagtagtcga cgaatagact ctgaagggat tgccgcataa ttatcgatga
     6421 aaacccgggc aaggccttta ctgaaccgtt tatggtcgtg ttcattcaga tgtggaacaa
     6481 tttcctgtac ggcttcatgc aggcgcagaa tgacataacg ccagggaaca gtatgttttt
     6541 ctcgtttatt gcgttcgact tcctggagat tttcttctgc ccagtcaaat gggtcgcgtt
     6601 gtttgcgctc ggcaaaccag gcttgagcaa aggaatcgac attcaggctc tctaaggcta
     6661 tgcgttggct ccagtctgga tcagcaaact tgatttcctc tactatcaat ctaaataccc
     6721 gatccaaaag gcccacttcg cctttttgaa tctcagcatt taatgcctga tcggtgatga
     6781 tgtgtaaggg ctcgtaggga atagggcaat agaaatcggc ttcgggtaaa atacctgtgc
     6841 gcgacattaa cgtaatattt agcttttcat ttgcgttatc gcggtgaaaa gtgacgtgtt
     6901 gtttatcatc ttcaatgaac gaaccatgct gaatagccac tgccattgcc gcatccagtc
     6961 cgctcaagga tgttcccata atacccacgt tacacgcatc gacctttgct tccatcaggc
     7021 ctgaccacgg gctgggaaaa tacgttctgg ttgcttcttc ttcatcaggc cagacgtgcc
     7081 ccgttgcgat caccgctaaa tcaaacgtct cgctgggtaa attcagattt gtagcgagca
     7141 tgacgccagc atttgtaatt tgcagatcgg taacctggca tgattcataa acagccactg
     7201 caaatttttg ctgtcgtgcc tggtctacta atcgtaaaaa ttgatcgcgg aaatattcgc
     7261 ccagcagaat tcgcggtaaa aactgacgat cgtgcaaggt ttctttttta acgccataac
     7321 gctggagatg gctggcttct tgcttttgta gccattcgag atacgtgcaa taaatcggcg
     7381 gtatttcaat actggcaatg tttgccagca tcagttttga gttttcctca tcactgtatg
     7441 gcatcccgat accggcttcg tcagcctgat cgaagataga aatagaaagt ggcgtttgtt
     7501 gctgtagaag cgagaataag gtgtagatcc ccgtaggccc ggcacccaca atagcaattg
     7561 ttttcattgt tacttacctg tacgcattct ttcgaattta gtgttatcag gtaagtttgg
     7621 ttgagatttt tagaatttga gaaatttcag acagggatga aaagggcact aaccgccctt
     7681 gattaaaatc tgtcaggcaa gttttgcctg attgatttga ctcagtggca cattgacatc
     7741 gaaaactttg gcgacaactt cctcaacgcc gagatttttc agtcgggcag tatgtttttc
     7801 cagataggca agggcgcttt tttcatcagt gaaaaggtag atcccaccgg cttcgtggtt
     7861 cttttcactt tctgtccaaa ccttccacag aaaaccaggt tcctgattaa tcgactcagc
     7921 aagcggttta agctgctcag ccattgtgtc gccaaatggg ccattgaaag aaaaatgaag
     7981 ttgtaacaaa gttgccatag cgattctcct tctgataacg catacgaaga cagtgtaaat
     8041 cttttaacgt attggataca gagaagaaac agagggaaaa aaggagaaga ccagattaag
     8101 aaaatctggt gcgtccgagt ggactcgaac caccgacccc caccatgtca aggtggtgct
     8161 ctaaccaact gagctacgga cgcaggatgg tgcgttcaat tggactcgaa ccaacgaccc
     8221 ccaccatgtc aaggtggtgc tctaaccaac tgagctatga acgcaacgtt gtaggtgaca
     8281 acggggacga atattagcgg cagagtggga aggtggcaag aggcaaaacg taattttctg
     8341 cgctatttcg accgtttgca gagcttttaa gcaaattggc tatattttgt tgatttgcaa
     8401 gggcgatttt tattcaggat cgcatttaca tctgatacaa cccaataatc cgtgtatcag
     8461 agtttaaaca gagttgtttg ccaccatctc aaatctgtcg tggataaatc cttcgtagcc
     8521 tttacactta ggtagcaata aaggcacaca gatgcagcaa aggaataaat catgggatct
     8581 gatgcgaaaa acttgatgag cgacgggaac gtgcaaattg ttaagaccgg cgaggttatt
     8641 ggcgcgacgc aacttactga aggcgagttg attgttgaag ctggcggaag agccgaaaat
     8701 accgtggtca cgggggctgg ctggttgaaa gtggcaaccg gtgggatagc caaatgcaca
     8761 cagtacggta acaatggcac actatcggtc agcgacggtg ccattgccac agatattgtt
     8821 cagtccgagg gaggcgcaat tagtctctct acgctcgcta cggttaatgg ccgccatccc
     8881 gaaggtgaat tcagcgttga taaaggttat gcctgcggtt tgttgctgga aaatggcggt
     8941 aacctgcgtg tactggaagg ccatcgcgcg gaaaaaatta ttctcgatca agagggtggc
     9001 ctgttggtca atgggacaac ctcagcggtc gtggtagatg aaggtggtga attgttggtg
     9061 tatccaggtg gggaagcctg caattgtgag attaatcagg gcggcgtttt tatgctggcg
     9121 gggaaagcca gtgatacgtt gcttgctggt ggcaccatga ataatctcgg tggtgaagac
     9181 tctgacacta ttgttgagaa tggagccatc tatcgtctgg ggacggatgg tcttcagctc
     9241 tacagttccg gtaagacgca aaacctgtcc gttaatgtgg gtggtcgggc tgaagtgcat
     9301 gccggtacgc tggaaaatgc ggtaatacaa ggtgggacag tgatcctgtt gtcacccacc
     9361 agcgcggacg aaaattttgt cgtagaggaa gatcgcgcac cggttgaact gaccggtagt
     9421 gttgcattac tggacggcgc ttcaatgatt attggctatg gcgcagatct gcaacaatca
     9481 acgattactg tacagcaggg cggtgtattg attctcgacg gcagtacggt aaaaggtgac
     9541 agtgtcactt ttggtattgg taacatcaat ctaaatggcg gaaaactgtg gctgatcact
     9601 gatgcggcaa cgcatgtgca actgaaagtg aaacgcctgc gcggagaggg agccatttgc
     9661 ctgcaaacca gtgcgaaaga aatttcacct gacttcatca atgtgaaagg ggaagttact
     9721 ggtgatatac acgttgagat aacagatgcc agtcggcaaa ctctgtgtaa cgcactgaaa
     9781 ctacagccag acgaagacgg gattggcgca acgctccagc ctgcgtaaaa acacaggcgc
     9841 aacccgtgaa ggttgcgcct tgtctttact agcgagctgc tcgttgcaga atgatggctg
     9901 acggcagacg ttgcaggaac cgcatacgca gcatcatcat aatggctgcc gaagtcaggc
     9961 caataataaa gcctatccag aagcctgctg gccccatagg ttcaacgacc agatcggtca
    10021 gtgccagaat atagccgctt ggcaagccca gcacccagta agccgtaaag gtgatataga
    10081 aaatggaacg tgtatcttta taaccacgca aaatcccact gccaatcacc tggatagagt
    10141 cagaaatctg atataccgcc gccagcagca tcaaatgcgc agccagcgtt acaacctcgg
    10201 gattgtcgtt gtacaacagg gcgatttgct ctcgcagtga aaccgtgaat atggccgtca
    10261 gggttgccat acagacaccc accataagcc cggtccgcgc agcggtttgc gcatccagcg
    10321 ttgagccttg acccagacga taacctacgc ggatggttac cgctgccgcc agcgacatgg
    10381 gaagcacgaa catcagtgaa ctaaagttca gggcaatctg atgtcctgcg acatcaacaa
    10441 taccgagcgg agacactaac agagccacga cggcaaacag cgttacttca aagaacagtg
    10501 ccagcgcaat tggcaaaccg agttgaatca gtcgtttcat aaccgcagga tcgggcttcg
    10561 cggtgccttt ttcgttacga atatcgcgca tcgagcgggc gcgtttaatg taagaaacca
    10621 tggcaaggaa catgacccaa tacaccgccg cagtagccac gccacaacca acgccaccga
    10681 gctcaggcat accgaaatga ccataaataa agatatagtt caccggaatg ttcaccagca
    10741 ggccgataaa gcccatcacc atacccggct tggtttttgc cagaccttca cactggttac
    10801 gggcaacctg gaagaaaaga tagcccggcg cgccccatag caacgcacgc agataaccca
    10861 cggctttgtc cgccagagcc ggatcgatgt tttccatgga gcggataatg taacccgcat
    10921 tccacagtac cagcataatg agaacggaaa caaaacctgc cagccagaaa ccttgtcgca
    10981 cctgatgcgc aatgcgctca cgtcgaccgg aaccatttaa ttgcgcgata accggcgtta
    11041 atgccagcag cagtccgtga ccaaagagga tcgccggaag ccagatagaa gttccgatag
    11101 caaccgccgc catgtcggtg gcactataac cgcccgccat cacggtatcg acaaaaccca
    11161 tcgcagtttg ggcgatttgc gcgagaatca ccgggattgc taatgctaat aacagacgcg
    11221 cttcactgat atacttctgc acgtgaacac cttttatttg tagttatatg agagactaaa
    11281 aagccgcctg aatgggcagc aaaaagaaga agcaggggaa attcagtcta ttgtagcgag
    11341 gatttattaa ttctccagtg aaaaaatagc cattcttacc ccttcactgg taagggcgtt
    11401 ttccacctgc tattgtgctg aacagaatgt cttaactgat ttcaggagtt gtaagtatgt
    11461 ttacggggat tgtacagggc accgcaaaac tggtgtcgat tgatgagaaa ccaaattttc
    11521 gcacgcatgt ggtggagtta cccgaccaca tgctggacgg actggaaacc ggtgcgtccg
    11581 tggcgcataa cggttgctgc ctgaccgtga cggaaattaa cggcaaccat gtcagttttg
    11641 acctgatgaa agaaacgtta cgcattacta atcttggtga tttaaaagtg ggggattggg
    11701 taaacgttga gcgtgcggcg aaattcagcg atgaaattgg cggacactta atgtcaggtc
    11761 atattatgac caccgctgaa gtggcgaaaa tattaacctc ggaaaataat cgtcagatct
    11821 ggtttaaagt ccaggatagt cagttgatga aatatatcct gtacaaagga tttattggca
    11881 tcgacggtat tagcctgacc gtcggcgaag tcacgccaac gcgtttttgc gtccatttaa
    11941 ttccggaaac actggaacgc acgactcttg ggaagaaaaa actcggcgca cgcgtcaaca
    12001 ttgaaatcga tccacaaact caggcagtgg tagatacggt agaacgtgtg ctggcggcac
    12061 gagaaaatgc catgaatcaa ccaggtacag aagcctgatc tgaaatcgcc cccggagcgg
    12121 gggcgataga atagccttta gcgagcgact cgaaggccgt tttcaacacc gcgtgagaac
    12181 acgacctgcc agagctgaat atcacgggcg cggaaagcac ctgcacaggc attcagataa
    12241 taggtaaaca tccgtttaaa gcgttcactg tagttatccg caatttctgg ccatgcggcg
    12301 aggaatcgtt cataccacgc catcaacgta gtatcgtaat cagcaccgaa gttatgccag
    12361 tcttccatca caaagtgggg ttcgctggac tgagctatct ggcgtacaga gggcaggcaa
    12421 ccgttcggaa aaatatattt attaatccag ggatcaacat tcagatcggt ttttttcgaa
    12481 ccgatggtat ggagcaggaa tataccttcc ggtttcaaat tacgatccac caccgcaaaa
    12541 taggtatcgt aatttttcgg tccgacgtgt tcgaacatcc ccacagaaac aatacgatca
    12601 aactggtcgt tcaggtcacg ataatcttgc agcaaaatgg tgacatccag gccttcacag
    12661 cgttcctgag ccattttttg ctgttcggca gaaatggtga cgccgaccac gcttacgtca
    12721 taattagacg ccatgtagtg cgccagtccg ccccagccac agccaatatc cagtacgcgc
    12781 atccctggtt ttaactgcaa tttttcacaa atcattttga gcttcgcctg ctgggcagat
    12841 tccagattat cggcatcttt ccagtaagca caggaatatt gcatgaaggg gtcaagcatg
    12901 cggctgaaca agtcattacc caaatcgtaa tgctctttgc cgactatcca ggcacgtttt
    12961 ttactctgca gattgaagag acgagcgccg gcaatacgca gcgtgtcttt gaaatgatgg
    13021 ggaagttggt tctcgagacc tgcgcgtaag actttgctaa aaaacatatc cagtcggtca
    13081 cattcccacc agccatccat ataactttcg cctaacccca acgatccttc ctgcagaacg
    13141 cgtttaaaaa aatcggggtt tttgacacga atatccgccg gggcagaacc gttaatggct
    13201 ataccggcac ggctaagtaa ttcgttggcg atacggtacc agttgtcatc tggtacactg
    13261 acttcttcta tacacgatga actcatagtt tctccatcac tggtcggtga tcagaacctt
    13321 aaaacagcgt agacgctttt tgggctttgt gagaaatctc gcagaaaaaa ccgcgagtct
    13381 ataatccgac gtagaacaga gggaaaggag gaacccttgc cgaaatgacc atccatagtg
    13441 agtcgggaac gatcctgtcc ccgtaataac ataatattta tcgtagtttt aacaactcga
    13501 aattagtata ggccgctaat ttcaatcata caacaaaatt ttgttagcag cctaagtata
    13561 agtatatcga tatagatcag tgtgattcac tatgagcgac ttcggcattg ccatgattct
    13621 ggcagccaac ttcttcacaa cgttgcatca tgtaacccag agcgaccagc actactgttg
    13681 ataacatcac gctggtggtg gtgagcaatg gcgtactgat actgataagc caggaaacta
    13741 ccagacttgc gaggaagcac agacccagtt gcagagtgtt ctgcaacgct gcggcgcgac
    13801 cggttgcatg tgggaaggga cgcagcgcct gggcaacaac aatcgggtag atcgcgccgt
    13861 tggcaatcgc catcacacag aatgggatca ggatttcgac caacgacaca tggctaatga
    13921 agcccgcagc ccaggtcgca atgacgctga cagcaaacag taccagcaac cacggtaata
    13981 actgcttgcc ttgccatttc tgcagcgcgg cgcgacagcc ataaccacca atcagaaacg
    14041 cgatagtttg cgggacataa cttaaaccaa taactgccgg gctgtaaccc atttcactaa
    14101 ggatgaacgg tgaaccggtc agccatgcaa aaaaactggc tgaacaggct gcgtatatca
    14161 gcacgttgcc gcgataggtt ttagaacgta gcaggtcggt aaaggtcaga ccatcctgac
    14221 tattgttacg ggccttcgtc gtgggtttga gccagaaaat aggcagaatc agcaccacgg
    14281 taatggcaaa cagggtggcg aaaatcgcct gccaggaaaa atggaccagc agccagcttc
    14341 ctaacagagg agccagtgcc ggagatagac ccaccagcgg catgatggtc gcaaaaatac
    14401 ggttaacttt ctgtgaagga taataatctg tcactaatgc ttgccagata accgccgcgg
    14461 cgcagacacc cacagcctgt acaaaacgca atatcagcag cgtggcggcg ttttccaccc
    14521 acagcatccc cagactacct aacgcaaaaa ttgtcaggcc gatgaataac accggtttgc
    14581 gaccataacg gtcggagagt ggcccccaca gaagctgggc tgcggcaaaa ccggcaagga
    14641 acagactaag gctggcactg acagcagacg caggcgtttg caggtcggcc tgtatggcgg
    14701 cgaaagcagg cagatacata tcggttgcca gaaaaccgag tacgctcaaa cccgccagcc
    14761 agactaaaaa tcttttccca ggttgcatgt atattctcta aatctctcaa ttaaacaccg
    14821 ccgcaaagtg tagggagtga aattagtgtt gtgaaacggt aatatttgat gattggtttc
    14881 aaaaattttg caggcagact atgtggtcag aatattctct cgaagttgtt gatgcggtag
    14941 cgcgtaatgg tagttttagc gccgcagccc aggagttgca tcgcgttcct tctgcggtca
    15001 gctataccgt gcgtcagctg gaagagtggc tggcggtgcc gctgtttgaa cgacgtcacc
    15061 gtgatgtgga actgaccgca gccggggcgt ggtttctcaa agaagggcgc tctgttgtca
    15121 aaaaaatgca gatcacccgc cagcaatgtc agcagatagc gaacggctgg cgcggtcagt
    15181 tagctatcgc agtggataat attgtcaggc cagagagaac acggcagatg atcgttgatt
    15241 tttatcgcca ttttgatgat gtcgaactcc ttgtctttca ggaagtgttc aacggtgtct
    15301 gggatgcact ttccgacggg cgcgtggaac tggcgattgg cgcaacacgc gcgattccgg
    15361 taggcggtcg ttatgccttc cgggatatgg ggatgttaag ctggagttgc gttgttgcca
    15421 gccaccaccc gctggcgttg atggatggcc cgttcagcga tgatacgttg cgcaactggc
    15481 cgtcattggt gcgcgaagac acctcgcgaa cgctacctaa acgtattacc tggttgctgg
    15541 ataaccaaaa aagacttgtc gtgcctgact gggaatcatc ggcaacctgt atctcggcag
    15601 gattatgcat agggatggtg ccaacacatt tcgccaaacc gtggcttaat gaggggaagt
    15661 gggtagcact aaaactggaa aaccccttcc cggattcggc atgttgtctg acatggcagc
    15721 aaaatgatat gtcgcctgcg ttaacctggt tgcttgagta tctcggcgat agtgagacgc
    15781 tgaataagga gtggctgcgg gagccggaag agactcccgc aacgggtgat taacgacgat
    15841 agtcgcggaa cgggccgtca gccacggagc ggcgttcaat caaccgcgga tgcacttcaa
    15901 tggactgcgg ttcttcacgt ttgttgacga tacgatccaa cagcatgttg aacgctgttt
    15961 cgcccagcga atcttttggc tgatggatcg tggtcagcgc cggcgtaaaa tagcgggcgt
    16021 tgcgcacgtt atcataaccg atcagcgaaa catcctgcgg cacgcgcaga cccatttcat
    16081 cagcagcaca aagtgcgccc attgccatga tatcgccacc acagaagacg gcagtagggc
    16141 gatgcgactg cgacaggatt tgctgcatgg cgcgataacc ggattcaggt tcaaagtcac
    16201 cctgcacaat ccagctttcc ggcactttga tcatcgcttc ttccatcgcc ttcataaaac
    16261 cagcaagacg gcctgcgccg gtgttacgtt ccagcgggcc agggataacg ccgatttcgc
    16321 gatgaccgcg ttcaatcaga taacgcccgg ccatgtagcc gccttcgaac gcgttatcaa
    16381 tgaccgcatc ggtgaagtca gcttttgctt caccccagtc catcaccacc attgggatat
    16441 ggcgatactc ttccagcatc gccagcaacg gctctgggta ctcagaacac atcaccagca
    16501 gaccatcgac gcgtttttgc gccatcatcg acagataagc ccgctgtttc tcaagattgt
    16561 tccacgcatt gcccagaatc agggtgtaac ctttctggaa gcaatttttt tcgaccgctt
    16621 caatgatctc ggcaaaatag gccgcttcgc tgctggtcgc cagcaaaccg atagacttgg
    16681 tgtggttaac cttcaggcta cgcgccaccg cgctagggga gtagtgtaat tctttgattg
    16741 ctgcccacac ggcattgcgc gtttcttcag cgacgaaacg tgttttgttg atcacgtgtg
    16801 acacagttgt agtggaaacg tttgctcgtt tcgctacatc ttttattgtt gccattccat
    16861 ttcactccag accctaactt cagctcctgc aaattcgcaa ggtaaacgtt tgcctttaca
    16921 caccttacgc acaacaaaaa tgttgcggta cgccggaaaa acgacacgga gcgtcaggaa
    16981 ggggtcaatg gccagtacgc aaatagtgta agcgtggaat tttggccgat cttgacgaaa
    17041 aggggaagta gtaaaaacac ttatcattat aaatgacggg agattttttc atcacagtgt
    17101 gtaaaaatgc gtaatatcac tttttgtgtg gtaataaaaa aggagaaaac ttgatgagca
    17161 ccgaccttaa attttcactg gtaacaacga ttatcgtcct cggtttgatc gtggccgtgg
    17221 gtttgactgc cgcgctgcac tgatttcctc tcgagggagc gcgttctccc tcgcatctcc
    17281 ttcctgtttg ttagcaaaat ggcaaaagtg ttttctcttt ttgttatttt catttttttg
    17341 tgattactgt catgctttcg ccactttaat gaatatcgcg taatgacgcg aagaggtgga
    17401 gataaggcat gaaaattaac tatccgttgc tggcgctggc gattggcgcg tttggtatcg
    17461 ggacaacgga gttctcgcca atgggcttgt tgcccgtcat tgcgcgcggt gtggatgtct
    17521 cgattcccgc tgccggaatg ttaatcagtg cttatgcagt tggcgtaatg gttggcgcgc
    17581 cgctgatgac gcttctactt tctcatcgtg cccgccgcag tgcgttgatt ttcctgatgg
    17641 cgattttcac gcttggcaac gtactttccg ccatcgcgcc ggattatatg accctgatgc
    17701 tttcacgcat tttgaccagc ctgaatcacg gggcattttt tggtttgggt tcagtcgtgg
    17761 ccgcaagcgt agtgccaaaa cataaacagg ccagcgcagt tgccactatg tttatggggt
    17821 taaccctggc aaatatcggt ggcgtgccgg cggcgacctg gttgggcgaa accatcggct
    17881 ggcggatgtc atttctggca acagcggggc tgggcgtgat ttcaatggta agtctgttcc
    17941 tctcattacc taaaggtggc gcaggggcgc gacctgaagt gaaaaaagag ctggcggtat
    18001 taatgcgtcc gcaggtgctg tctgcattgc tgacgacggt actgggcgct ggtgcaatgt
    18061 ttaccctcta cacctatatc tctccggtac tgcaaagcat tacccacgta acgccggtgt
    18121 tcgtcacggc aatgctggtg ctgattggtg tcggattctc tatcggtaac tatctcggcg
    18181 gcaaactggc agatcgttca gttaacggca cgttgaaagg ctttttgttg ttgctgatgg
    18241 tgattatgct ggcaatcccg ttcctggccc gcaatgagtt cggcgcagct attagcatgg
    18301 tggtgtgggg agctgcaacc tttgcgatcg taccgccgtt acagatgcgc gtgatgcgtg
    18361 tcgccagtga agcgccaggt ctgtcttcat cagtcaatat tggtgccttt aatcttggaa
    18421 atgcgctggg agcagctgct ggtggtgcgg taatttccgc tgggctggga tacagttttg
    18481 tgccggtgat gggggcgatt gtcgcgggac tggcattatt gctggtgttt atgtcagcca
    18541 gaaaacaacc tgaagcagtt tgcgttgcca acagctaatt aaacaaaaac gcagaaggat
    18601 aaccttctgc gttacagttg ctggcaacgt gcgatttatc ttgccgaatg cgctgttaac
    18661 gcctcatccg cgttggcatg gtaagcgaag cgcatcaggt aatgttgcat ttgccatcag
    18721 ttattatgca gcgagatttt tcgctacgaa ttcccagttc accagcgccc agaagtgctc
    18781 cagatagcca gggcgtgcat tgcgatagtc gatgtaataa gcgtgttccc agacatcaac
    18841 ggtcagcagc ggagtcgcat cggtggtcag tggagtaccc gcgttagagg ttgaaacgat
    18901 agccagtttg ccatcgctgt ttttcaccag ccaggtccag ccagaaccaa agtttttgat
    18961 cgctgcatca gtaaactgag ctttgaaatc ggcaaagctg ccaaaagatg cggcgatagc
    19021 ttcagcgact tttccagtcg gttcgccacc cgcgttcggt gccaggcagt tccagtagaa
    19081 agtatggttc cagacctgag ctgcgttgtt gaatacgcca ccttcagagc tgcgaataat
    19141 ctcttccagt ggtttacctt caaacgcggt acctttgatc aggttgttca ggttagtgac
    19201 ataagtctga tgatgtttgc cgtagtgata ctcgatggtt tccgcagaaa tgtgcggtgc
    19261 cagagcatct ttagcatatg gtagtgcagg taattcgaat gacattgcta ctctccttta
    19321 ttattaattt gcatacgtac aatagcctta ttgtgcgtat ggatagggta gcaaattaaa
    19381 aggtgagaca aaagatgaac ttaccctgtt gccgtaacaa cagggtaaag ttttagcgaa
    19441 gtgtttttgg ggtcattacc cggcgagcgc caacatagtg gcgctgccag tagtcttcac
    19501 tgagagaagt gatttgaatt tcctggcccg tgcgcggtga ctgaataaat ttgccgttgc
    19561 cgacatacac gccgacatga tcggctgtac cgcgtccctg agtacggaag aagaccaggt
    19621 cgccgttttt cagttcacta cgttcgattg gcgctgcatc gcgcaggtga tacatttcat
    19681 tcgccgtacg cggaatacga attttcacca aatctttata agcgtaataa accagaccgc
    19741 tgcaatcaaa accggtacgc ggtgagctgc caccccaacg atatggctta ccaatttgct
    19801 gcatcagttt attcattgcc acttttgtgg ctttttgcac cttcgctttg tgcgcgtcgg
    19861 caagggttcc tgacgcggca tttttgactt tcacacaatg cgatttatag cccttacgtt
    19921 tggtacactt ttcggtaaag ctggctgagg ccgttttatt gacggcgtgt ttgctgcgag
    19981 ttttggcgtt tttagaagcg gtaatggaag attttttaac ggaagaagcg gttttgcttt
    20041 tggtcgtact tttactggcg gcttttttcg ctgttttctg gctggctttc tgggtctttt
    20101 gggtggttgc cgtgcttttc tttttatctg cttttttggt gatatgagtg gtagcagaac
    20161 tctccctggc ttgctttgaa gcatgggcca taggcgttaa aggcagggtg gtaaaaagta
    20221 aagcacagag cgtgatcgaa atacggttta tccgcgccac tgagcgtccc tctgttaagg
    20281 caggtctatc atgcctgcgt ctgatttaca aaacttgatg attctaatgc atagaagaag
    20341 agaaagttaa tagcttttat tgttaaaaaa tacgtttcgt cggcgagcgc aaaaaaatgc
    20401 agcagtgaaa gctaaaaatg gttataaata cgccagtttg ccgtgcatca gggaagaaac
    20461 gaatatttga aatgcaacaa atagagcaaa gggataaaat agcaaaagcg tgatgaaaat
    20521 gttattttcc gatgccgcac tgacccgcta caatgtcaga ttactgccgt aaagaagttt
    20581 gaggaagcaa gacaatgagc accactatcg aaaaaatcca acgccagatt gctgaaaacc
    20641 cgatcctgct gtacatgaaa ggttcaccga aactgccgag ctgcggtttc tctgcccagg
    20701 cagtccaggc gcttgccgca tgtggcgaac gttttgccta tgttgatatt ctgcagaatc
    20761 cggacattcg tgcggaactg ccgaaatatg cgaactggcc gaccttcccg caactgtggg
    20821 ttgacggcga gctggtgggc ggttgtgata tcgtgatcga aatgtatcag cgtggtgaac
    20881 tgcagcagct gatcaaagaa actgccgcta aatacaagtc tgaagagccg gacgcggaat
    20941 aatccgtcct gcaatactga cggatgcgaa cgggcatccg tcagtccttt ctctatcccc
    21001 aatccagccc ttgtggcgaa cttgaaaatc ccgcctcacg taacagcgta aacatcggcg
    21061 tttgccggac cggtaggtca ttcacttctg ttagcgtaaa gcgcagccgt ggttcgcgac
    21121 tagacagcgg tcggctgttt aaaggcgcga agaaaccagt cgcgggtcgc cggcgaaaac
    21181 acgtccggca ggggcgatga agggtttgga ttatttgcca ttaacgctat tccccgtgaa
    21241 tatcatgcat gatgcgtgga atagcctcac tatagatgcc tgaatcattg catgtcatca
    21301 ggcatcgact cgattacacc tctgcggcgg caggtagtgg ccagcctccc agacgtttcc
    21361 agcggttgac gatttcacaa aacagcacag cagtgcgttc ggtgtcgtac agcgcggagt
    21421 gcgcctgggt gctgtcgaag tccatgccag ctgtctggca agcctttgac aatacggttt
    21481 gtccgagtgc cagcccggcc agtgcagcag tgtcaaaagt ggcgaaaggg tggaacgggt
    21541 tacgtttcag tgaggcgcgt tctgcggcgg ccatcataaa gctgtgatcg aaattggcgt
    21601 tgtgcgccac cataatggcg cggttacagc cgctcgcttt aataccttta cgtacaactt
    21661 taaaaatttc gtgcagcgcc tcgtactcgc tgaccgcgcc gcgatcggga tcgttcggat
    21721 caatgccatt gaaggcaagg gcctctggtt gcaaatttgc gccgacaaat ggttcgacgt
    21781 ggaaatgtaa tgtggtgtcc ggcatcagcc agccttgttc atccattttc agggtgatgg
    21841 cggcaatctc aagcagcgca tcggttttgg cgttaaatcc ggctgtttca acatcgatca
    21901 caacaggata aaaaccacga aaacggtcgc acagaccggt aagttgagcg ttatcggaca
    21961 tctgattctc ttaatacgga taaattgcag cgcgcattat gacaaatatt acttgtcgat
    22021 gcagtaaaga tgcgggcgcg atgagttcac gcccggcagg agattagttg cccagaccgc
    22081 gaccggcgtc tttctcttcg attaattcaa ttttgtaacc gtccggatct tccacaaatg
    22141 cgataaccgt agtaccgcct tttaccggac ccgcttcacg ggttacgtta cccccgtttt
    22201 gacggatttt ttcgcacgct tcagcggcgt tatctacgct aagcgcgatg tgaccataag
    22261 cagtgccgag ttcgtattta tccacgcccc agttgtaggt cagttcaatc actgcttctt
    22321 cggtttccgg gccgtaacca acaaacgcca gtgagtattt gtattccggg ttttcgctgg
    22381 tacgcagcag tttcatgccc agcacgttgg tataaaaatc gatggagcgt tgcagatcgc
    22441 caacgcgcag catggtatga agaagacgca tctttatatc ctcaaaatgg ctaacagatt
    22501 caaaaagttg ttttagtata gcggcggctt tgcgccgctc gcaatgttgg attacagcgt
    22561 cgggtaatca gtgtaacctt cagcaccgcc accataaaaa ctttcggcac gctgcgggtt
    22621 aagctcagct ttgcgctgca agcgggcgac cagatccggg ttcgcaatcc agtcacgacc
    22681 aaatgctacc gcatcaatta accctttgcc gatcagcgtt tcagcttttt ctactgtgta
    22741 tgcacctgcg ccgataatcg gaccgtggaa acgggcgcgt actttttcgc gaaacgcatc
    22801 agtatatggt tcacctcccg cccaatctgg ttctgacata tgaagataag caatgccgcg
    22861 tttacccagt tgttcaatca gatacagtgc atcggcttct tcattcgggc cgttatccgt
    22921 gttctggaaa gtaccgattg gcgaaatgcg aatgccaatg cgatcggcac cccattcttc
    22981 aatcccggca tcgaccactt ccagcaccag acgcgcgcga ttttccacgc tgccgccgta
    23041 ctgatcggta cgatggtttg aagaagggga aaggaactga tgcagcaaat aaccgtgagc
    23101 agagtggagc tctaccagat caaaaccggc ttcacgcgcg ttagcaatgg cctgacggaa
    23161 atcattgacg atacccggaa tctcttccag ttcaagcgca cgcggcatgg atgtttcaac
    23221 acggatcgcc tgaccatttt catcgcgcag agaagtacgt gttcccgcgc taagtgctga
    23281 aggcgctacc ggtgcctgac cgccaggttg caggctggcg tgagaaatgc gtccggtgtg
    23341 ccacagctgt acggccatat gaccattttc agcatgaacg ccagcggtaa tttttttcca
    23401 tgcggcaatt tgttccgggc tatggatgcc aggtgcacct gcgtatcctt ttgcctgggc
    23461 agaaatttgc gtggcttcgc taataatcaa accggcactg gcacgttggc gatagtattc
    23521 cgccatcaac ggggtaggga tgtcacccgg ttcaatactg cgcagacgcg tcagcggtgc
    23581 cataaaaata cggtttgccg ccgtgatcgc gcccactttc agtggggaat acagtttttc
    23641 agatgacata aaggctcccg gtcgtctggt gataaaaaat gcctgctaaa cggcaggcgt
    23701 cgcaataatg ttttttacat gggccagcgc gttttccagt ggctcgaaac tgcgcgaaat
    23761 tttggcctgc aaattcgcac caagccacag tgcgtaaagc acttgtgcct gttgcagcgg
    23821 ttcgccacaa aaggttaaac aatggttctc acggccattt tccagcgcct gagagagcag
    23881 ggcgatcacg ccgcgagccc ctttatccat tgcgctgcgc atatcttctg acagatcgca
    23941 cacttcggca gagagtttta ctgtcaggca accactgatg gttccatgtt ggcaaaactg
    24001 gttcagtgtt tgctggtaat aagccagtat gcggtcgcgg tagttacctt cgccggattg
    24061 cagcaactca gtcagtcgct ggtgatatgc ggcgtaatgg cgctcaagca tggcaacgcc
    24121 aaacgcttct ttagaacgaa agtagtgata gaaggaccct ttcggcactt cagcggtttt
    24181 taggagttcg cttagcccca tcccggtgaa tccacgttgc aggcaaagtt gctcgcccgt
    24241 cgccaggaga tgttcgcgag tatcatgttc ggtgtgtttg ttcatgcgtt ggagtgtagt
    24301 agaccagtcg gtctagtgca agcaaagttg ctactttgga cattaacagc ttcaataatg
    24361 gtaataatct tatctgagga gggcgaggtg acggagcaat tagagttctt tcccgtccag
    24421 agcccgtgcc ggggaatttg ccagtctgac gaacggggat tttgtcgcgg ctgttttcgt
    24481 agccgggatg agcgttttaa ctggaataaa atgagcgatg gcgaaaaaca agaagtgttg
    24541 cgcctttgtc ggcagcgatt aatgcgcaaa ttacgtgcaa ataagccagc gtcatcagac
    24601 gaaccggagc aaccatcact cttttgagcc taatcttgcg tatactcctc tcatatctga
    24661 taagaggaag cgattatggt tcagcgtatt actattgcgc cgcaaggccc ggagttttcc
    24721 cattttgtga tgggctactg gcgattgatg gactggaaca tgtccgcccg ccagttggtc
    24781 agttttattg aagagcatct ggatctcggc gtgaccaccg tggaccatgc tgatatttat
    24841 ggtggctatc agtgcgaagc ggcgtttggc gaggcgctga aactggcacc tcacctgcgt
    24901 gaacggatgg aaatcgtcag taaatgcggt atcgcgacga ccgcgtgtga agaaaacgtc
    24961 attggccatt acatcactga ccgcgatcac atcattaaga gcgccgaaca gtcgctaatt
    25021 aatctcgcga ccgatcatct ggatctgctg ttaatccacc gaccagaccc gttaatggat
    25081 gccgatgaag tggcggacgc ctttaaacat ctgcatcaga gcggcaaagt gcgtcatttt
    25141 ggtgtatcga actttacacc tgcgcaattt gcgctgttgc aatcacgcct gccatttacc
    25201 cttgccacta atcaggtgga aatatccccg gtgcatcagc cgttactgct ggatggcacg
    25261 ctcgaccaac tgcaacaact gcgtgttcgt ccgatggcgt ggtcctgcct tggtggtggt
    25321 cgtctgttta atgatgatta tttccagccg ctgcgtgatg aactggctgt ggtggcagag
    25381 gagttaaacg cgggctcgat tgaacaggtg gtttacgcct gggtattacg tttaccgtcg
    25441 cagccgctgc caattatcgg ctcaggtaaa attgagcgcg tacgggcagc agtcgaagca
    25501 gaaacactga aaatgacccg tcaacaatgg ttccgtatcc gtaaagcggc actaggttac
    25561 gacgtaccgt aagcactttt aggaatagcc gccgttcaaa aatgtgtcac tggtttacac
    25621 ttattcagga atgcacaatg aacggaggtc ctatgaaacg ttttagtctg gccattctgg
    25681 cgctggttgt tgcgaccggc gcacaagctg ccagtgaaaa agtcgagatg aacctcgtca
    25741 cgtcgcaagg ggttgggcag tcaattggta gcgtcaccat tactgaaacc gataaaggtc
    25801 tggagttttc gcccgatctg aaagcattac ctcccggtga acatggcttc catattcatg
    25861 ccaaaggaag ctgccagcca gccaccaaag atggcaaagc cagcgccgca gaatccgcag
    25921 gcgggcatct tgatccacaa aataccggta aacatgaagg gccagaaggt gccgggcatt
    25981 taggcgatct gcctgcactg gtagtcaata atgacggcaa ggcgaccgat gccgtcatcg
    26041 cgcctcgtct gaaatcactg gatgaagtca aagacaaagc gctgatagtc cacgttggcg
    26101 gcgataatat gtccgatcaa cccaaaccgc tgggcggtgg cggtgaacgc tatgcctgtg
    26161 gtgtaattaa gtaattaaga ggccagcgta ccttgcggcg gtgcttgctc aagttgcgaa
    26221 agcgagcagt acagccgcca gacaattgcc gccagttctc gggcggcagg ttgatgatga
    26281 cgggcaaggc tgtcgcaaat ccgctgtaat tcttcaagtg tggccgccag tgatttttgc
    26341 tgaacgccac gctcactcat cactccccgc aacagtgaaa tacagttatc ccgtactcgc
    26401 gataacggat cggaacgcga ttcccagtcg cgcaattgcc agacaacatg agaacagttc
    26461 agcaacacta caccccagcg taataaccaa cggcgagcca gcgcatcctg gctgttactc
    26521 aactgactga cgtgatgata agtgagcgat tcaaattcgc tttcactcag tgttggatgg
    26581 cggcttagtt gatcgacaaa atcccggcgc agcgcgcgaa tatggcggcg gcttttacga
    26641 gcatccgatc ctggacgcag aatggcgaac gctaaccacg ccaacgcgac gccaacaatt
    26701 tttgccagat tatcgttaag aaaatcagca aaatcataca ccgggggatt agtgacagcg
    26761 ataaacgaac ccataaaaac aatcagttgc ccccacagtg cggcaaattt gggcatctgc
    26821 aatttaagaa gctgcattgt cgccagcagt ggaaagagaa acagtaaaaa ttgccacaga
    26881 tcgctaatct gcaccatcag gccaaatttg accacaaagc tgaatagcga aagtaacacc
    26941 agcgtgcgca tcagcagtga caaagactta aacggtgctg cgacggcgga gtagagtacg
    27001 cagctaattg ctgccagcgt taaagcattg gcaccggcat cccattgcga agcaatactc
    27061 catgcgccaa tcatcatcaa cgtacaaaat gtacgcagcc cgctccacat agcttcggcg
    27121 ttatcggtat gacgagccag gccggatgtc cgtgggagtc tggcatgatc atctacaccg
    27181 ctttgtagac gatgtaattc ctgactactt tgcagataaa ggcggcaaaa ataacgtagt
    27241 cgctgccaga aggcgatgtg ccggtagtcg gtgacgttgg tcgggcgtag tggggagata
    27301 atacgtgcga cggtgtaaac atctgtttgc gaactggcga gcgccgtcag cagctgttcg
    27361 agaatttctc gcgtggcatc tggcggtgag ggccagttga gcaacatacg tcgcaggctg
    27421 gagatgacac tggtcatacg taattgctgg tggagcagcg cattaaggcg tgcgttttgc
    27481 tggcgaaaac gatagtggct ccagaaagcc tggatacgca gcaaattcat ggtcagtatc
    27541 tgcccaatca ccccttcatg tgctgcacga atggcatcgg ttgtttcagg ccgccagagt
    27601 aaactggcat gttccagtaa tcgggcgtgc atgtttttca atgcggttaa aagggctgta
    27661 gcatcggaac tgctcggcag gatcatcatc atcatgccgc cgcacaaaat accgactatc
    27721 acctcgcaaa cacgcgcctg agcgatatcc cacagctggc tggcctcagt aatattaacc
    27781 atcggaaagg cgatgatggc agccgtgtag cccgccagtt gaaatgcata cgcgacgtta
    27841 ttcgtgaagt gcgcacaggc ccaggtacaa aagccaagcc acgccgacat gctcaataga
    27901 aaaaaccacg gctcattgag cgtatgtccg gcaagaagca gtgctgcaat ggctccgagc
    27961 aaactgccag cgatgcgtcc gaggcttttg ctgatgacac cgccaacggt gggaaagcta
    28021 accaccgcag ccgaggtcat cgcccaatag ggttcatcca gattcaaata ataggcaacc
    28081 gtcagcgcca gacacatggc aatggtattg cgtaacgcat aacgccattg cgccagcgtg
    28141 gccctgaacc agggcaaatt gcgcaaggac catgacgatg cgttcattat tgacctacgg
    28201 caatgctaca ggtggtgccc gacaccagcg tgacatcgcc tgggacttta tccagcgtaa
    28261 agcggacggg aacgcgttgg gcgaggcgaa cccaggggac gttaggtttc acatccggaa
    28321 taaggcttga gtcactttca acgctctgat cataaatcgc ccgaccgata ctggacacgt
    28381 gaccctgtaa cgttttgtta tcactataga gggtaatttg tgctggtgca ccttcgcgga
    28441 tatggcgcaa cttggtttct tcaaaataac caatgacgta aaacgagtgg ctgtcaacaa
    28501 gggcaaacag cggtttcccg gtgtcagcgt agtcgccgat gcgggtagtg agattagtca
    28561 cccatccact caccggggcg cgaatttccg tttgcgccag ttgccattgt gcctgtttca
    28621 gcgtcgcctg tgcggcatca acgctggcct gcatcgcttt aacattgagg ttagcggtat
    28681 cgagttcttc ggcagaaata aaattttgtg agagatgacg acgacgattc gcttcgttat
    28741 tggcttttgc gaggtcagat tgcgctttcg ccagctgagc ctgtgcgttc agctcggcga
    28801 tctgaaaggg cgttttatcg atcgtgagca gaagatcccc cgcgttaacc agctggttgt
    28861 cttttatatt cagctcaaca atacgtcccg acacctgtgg ggtgatagaa acctgttctg
    28921 cgcgtatttt cccgtcgcgt gtccacggag attgcatgta ataattccac agccaccatc
    28981 cggcaagaac cgcaactacc gctacaatga ttgttgagaa atacttaatt gttttaattg
    29041 acatagttac cacgcaatca gtattgccag agcaaggcaa acgcaaatcg caaacagcga
    29101 taaatccatt aacaagggat gccagatgtc accagcgtag atccagccac gaagcaggcg
    29161 gtgtatgaca agccagatga cgaatccaaa cgcgaaggct ttgaaaaacg gaggaaagta
    29221 gacggacgca ccgaacacca gatcttgtaa gggcaatcct gttgcattga gcataaactt
    29281 cacaaagtag attcctttac gacagaatat attgcgttag attaataaat attctttaag
    29341 tgcgaaaaat ttacgcgcaa tttctgaaaa atatgtctga cggtaaccaa atgcagcaat
    29401 acatttgttt tagcaataca attgctgcac actattctaa aagccgcata atatcttagc
    29461 aagctaatta taaggagatg aaattggaat cgccactagg ttctgatctg gcacggttgg
    29521 tgcgcatatg gcgtgctctg atagaccatc gcctgaaacc gctggagtta acacaaaccc
    29581 attgggttac gttacacaat atccatcagt tacctccaga ccagtcgcaa attcaactgg
    29641 caaaagcgat tggcatcgag cagccatcac tggtccgtac gctggaccaa ctggaagaaa
    29701 aagggttaat ttcgcgtcaa acttgtgcca gcgatcgtcg ggctaaacgt attaaactga
    29761 cggaaaaggc agagccactg atcagcgaaa tggaggctgt tattaacaaa acccgcgcgg
    29821 aaattttaca tggcatctcc gcagaggaac tggaacaact gattaagctc atcgcaaaac
    29881 ttgagcataa tatcattgag ttacaggcca aagggtgaaa tgaagggggc gtgtggtcag
    29941 taacctgacc acacgcaaac ttatttagcg cggggaaacg gtcacctgac tgccattgct
    30001 ggccagtacg acacgttggc ctggagagaa atgagtgttc ccttgtttct gtaccaccat
    30061 gatggtgttg ccatcatctt tacgaatttc cagctcgaca ccctgcgttt tgttcattgc
    30121 actctgtacg ccctgaccgg ctacaccacc tgcaacggcc cctgctgcag tagccagaga
    30181 acgcccggtt ccgccaccaa tagtatttcc caggaaacca ccaagtacag caccgccaat
    30241 tgcgccgata acgttggaat catcaccgcc ctgaatctgt acctgacgta cattaacgat
    30301 ggtgccatag ctgacattct gtacttgttt cgcttcagaa gcggtataaa catcccctga
    30361 cagggtgtcg ttattaacac aaccgacaag agacagacct accattgaaa caaccaatac
    30421 gcgtttaatc attgaaaaat ctcctgttca ccatgaaacg ccacgcaagc atccctcatg
    30481 gtcaaagtat atggcatatg tgaatccatg gttacatgtt ctaccaaata tgagcaaatc
    30541 ataatgaaag taggatcaac caattataaa caaaatattc atgatgatta ttgatttgaa
    30601 gataatgttt tactaccaac ggtaaaaatt ggtcattccg cgtggtattc acgaaaagtt
    30661 tatgtttgag tggtgcgcaa acgtcagatt gaaaaaggat gaactatgaa atcgggccgc
    30721 tttattggcg ttatgtcagg caccagcctt gatggtgttg atgttgtgtt agcgacaatt
    30781 gatgaacacc gggtcgcaca gctggcaagt ttgagctggc cgatcccggt gtctctgaaa
    30841 caggctgtac tggatatttg ccagggccag cagcttacac tttcgcagtt tggacagctt
    30901 gatactcaac tcgggcgact ttttgctgat gcggtcaatg ccttgcttaa ggaacaaaac
    30961 ctgcaggcga gagatatcgt tgcgatcggc tgtcacggtc aaaccgtctg gcacgaaccg
    31021 acgggcgtgg caccacacac tttacagatt ggcgataaca atcaaattgt ggcgcgcacc
    31081 ggaattacgg ttgtcggtga ttttcgccgt cgcgatattg ccctgggagg acaaggtgca
    31141 ccgctggtac ctgcgttcca tcatgcgctg ctggctcacc caaccgagcg acgaatggtg
    31201 ctcaatattg gcggcatcgc caatctgtca ctgctcattc ctggccagcc ggttgggggc
    31261 tacgataccg gtcctggtaa catgctgatg gatgcctgga tctggcgtca ggccggtaaa
    31321 ccttacgata aagatgccga gtgggcacgg gcgggtaaag ttattctccc actgctgcaa
    31381 aatatgctca gcgacccata tttctcgcaa cccgcaccga aaagcaccgg acgcgaatac
    31441 tttaactacg gctggctgga gcgccatttg cgccattttc cgggggttga tccccgtgat
    31501 gtgcaggcca cagtggcaga actcaccgcc gtgaccattt ctgaacaagt tttgttgagc
    31561 ggtggctgcg aacgattgat ggtatgtggt ggaggtagtc gtaatccgct actcatggcg
    31621 cgtctggcgg cattactgcc aggcacagaa gtcaccacca ccgatgccgt tggcattagt
    31681 ggcgatgaca tggaagcatt ggcgttcgcc tggcttgcct ggcgaacgct ggcgggatta
    31741 ccaggaaatc tgccttccgt cactggcgca agccaggaga cggtactggg ggctattttc
    31801 cccgctaacc cgtgatatca gagttaactg aatttttctt accgcgtctg ccgttacact
    31861 tggaacgtta gggagggcgt attgccctcc agaccaggaa agtcttcggg atatgtctat
    31921 gaaaaaactg ttactgatct gtttgccggt gcttctcacc ggctgtagcg cgttcaatca
    31981 actggttgag cgcatgcaaa ccgatacgct tgaataccag tgtgatgaaa aaccgttgac
    32041 ggtcaaactg aataatccgc gccaggaagt cagttttgtt tacgataatc aactactgca
    32101 tctcaaacag ggcatttcag cgtctggtgc acgttacacc gacggaatct atgttttctg
    32161 gtcgaaaggc gaggaagcga ctgtctataa acgcgaccgc atcgtcttga ataactgtca
    32221 gttacaaaat ccgcagcgtt gagatttttc caggggcggc gcacaatagc gtcacccact
    32281 gacaatccgt aaagaaaacc atgtctgata acgacgaatt gcagcaaatc gcgcatctgc
    32341 gccgtgaata caccaaaggc gggttacgcc gccgcgatct acccgccgat ccattaaccc
    32401 tttttgaacg ttggctctct caggcttgtg aagccaaact ggctgaccct accgcgatgg
    32461 tggtcgctac cgtggatgaa catggtcagc cttatcagcg catcgtttta ctcaaacatt
    32521 acgacgaaaa aggcatggtg ttttacacca acctcggcag ccgtaaagca catcaaatcg
    32581 aaaataatcc gcgcgttagc ctgctgttcc cgtggcatac ccttgaacgc caggtgatgg
    32641 tgatcggtaa agcggaacga ctttcgactc tcgaagtgat gaaatatttt catagccgcc
    32701 cgcgtgatag ccagattggt gcatgggttt cgaagcagtc cagtcgcatt tctgcccgcg
    32761 gtatccttga aagtaaattc ctggagctga agcagaagtt tcaacagggc gaagtgccat
    32821 tgccaagttt ttggggtggt tttcgcgtca gccttgaaca gattgagttc tggcagggcg
    32881 gtgagcatcg cctgcatgac cgctttttgt accagcgtga aaatgatgcg tggaagattg
    32941 atcgtcttgc accctgaaaa gatgcaaaaa tcttgcttta atcgctggta ctcctgattc
    33001 tggcacttta ttctatgtct ctttcgcatc tggcgaaaag tcgtgtaccg gcaaaggtgc
    33061 agtcgttata tacatggaga ttttgatggc aagcagtaac ttgattaaac aattgcaaga
    33121 gcgggggctg gtagcccagg tgacggacga ggaagcgtta gcagagcgac tggcgcaagg
    33181 cccgatcgcg ctctattgcg gcttcgatcc taccgctgac agcttgcatt tggggcatct
    33241 tgttccattg ttatgcctga aacgcttcca gcaggcgggc cacaagccgg ttgcgctggt
    33301 aggcggcgcg acgggtctga ttggcgaccc gagcttcaaa gctgccgagc gtaagctgaa
    33361 cactgaagaa actgttcagg agtgggtgga caaaatccgc aagcaggttg ccccgttcct
    33421 cgatttcgac tgtggagaaa actctgctat cgcggcgaac aactatgact ggttcggcaa
    33481 tatgaatgtg ctgaccttcc tgcgcgatat tggcaaacac ttctccgtta accagatgat
    33541 caacaaagaa gcggttaagc agcgtctcaa ccgtgaagat caggggattt cgttcactga
    33601 gttttcctac aacctgttgc agggttatga cttcgcctgt ctgaacaaac agtacggtgt
    33661 ggtgctgcaa atcggtggtt ctgaccagtg gggtaacatc acttctggta tcgacctgac
    33721 ccgtcgtctg catcagaatc aggtgtttgg cttgaccgtt ccgctgatca ccaaagcaga
    33781 cggcaccaaa tttggtaaaa ctgaaggcgg cgcagtctgg ttggatccga agaaaaccag
    33841 cccgtacaaa ttctaccagt tctggatcaa cactgcggat gccgacgttt accgcttcct
    33901 gaagttcttc accttcatga gcattgaaga gatcaacgcc ctggaagaag aagataaaaa
    33961 cagcggtaaa gcaccgcgcg cccagtatgt gcttgcagaa caggtgacac gtctggtgca
    34021 tggtgaagaa ggtttgcagg cggcaaaacg tattaccgaa tgcctgttca gcggttcctt
    34081 gagtgcgctg agtgaagcgg acttcgaaca gctggcgcag gacggcgtac cgatggttga
    34141 gatggaaaag ggcgcagacc tgatgcaggc gctggtcgat tctgaactgc aaccttcccg
    34201 tggtcaggcg cgtaaaacta tcgcctccaa tgccatcacc attaacggtg aaaaacagtc
    34261 cgatcctgaa tacttcttta aagaagaaga tcgtctgttt ggtcgtttta ccttactgcg
    34321 tcgcggcaaa aagaattact gtctgatttg ctggaaataa tgcattaagt ggaaaggggg
    34381 agtgagaaat cactccccct ggtttttata cagggaacat gatgaaaaat attctcgcta
    34441 tccagtctca cgttgtttat ggtcatgcgg gtaacagtgc ggcagagttt ccgatgcgcc
    34501 gcctgggcgc gaacgtctgg ccgctgaaca ccgttcaatt ttctaatcac acccaatacg
    34561 gcaaatggac cggttgcgtg atgccgccca gccatttaac cgaaattgtg caaggcattg
    34621 ccgccattga taaattacac acctgtgatg ccgtattaag tggctatctg ggatcggcgg
    34681 agcagggtga acatatcctc ggtatcgttc gtcaggtgaa agcagcgaat ccacaggcga
    34741 aatatttttg cgatccggta atgggtcatc cggaaaaagg ctgtatcgtt gcaccgggtg
    34801 tcgcagagtt tcatgtgcgg cacggtttgc ctgccagcga tatcattgcg ccgaatctgg
    34861 ttgagctgga aatactctgt gagcatccgg taaataacgt cgaagaagcg gttctggcag
    34921 cgcgcgaact cattgcgcaa gggccacaaa ttgtgttggt taaacacctg gcgcgagctg
    34981 gctacagccg tgaccgtttt gaaatgctgc tagtcaccgc cgatgaagcc tggcatatca
    35041 gccgtccgct ggtggatttt ggtatgcgcc agccggtagg tgttggtgat gtgacgagcg
    35101 gtttactgct ggtgaaactg cttcaggggg caacgctgca ggaggccctg gaacatgtga
    35161 ccgctgcagt atacgaaatc atggtgacca caaaagcaat gcaggaatat gagctgcaag
    35221 tggttgctgc tcaggatcgt attgccaatc cagaacatta tttcagcgca acaaagctct
    35281 gaaatatctc atttcggccc acaacgacct gtgggccgat ggctattact ttaagccttc
    35341 cgctgacagc gcgtcttgta cttccggacg ttcagccata cgttgcataa atgccgcaat
    35401 gtgctctaac ccttccagat tcagtttcac cgcgtatgcc cagcgcagaa ccgtaaacag
    35461 ataggcatca gcaattgtga atcgttgccc gcagatccag tgctcatcct tcagggcctc
    35521 gttcacatat tgcagcttct tctccagctg cgcgcgaact gtcggtttgt actcttccgg
    35581 tgtatcaggg cgaaacagag gtgtgaaacc tttatgcagc tcggtggcga tgtaattcag
    35641 ccattcgatg gttttatagc gggaaatact gtttaccggt gccagcaact ggcggtcggg
    35701 gacgctgtcg gcaagatact gcataatcgc tacgccttcc gtcagcaaag taccatcgtc
    35761 cagcagcaat gcaggtacct gtcccttagg gttaacggca aagtaatcgt caccgttttc
    35821 gagacgtttt ttcattaaat ccacactgac gagcgtaaaa tcctttccgc tctcacgcag
    35881 ggtgatatgg gaagcgagag agcaggcgcc cggtttgtag aacaatttca tcggtaactc
    35941 cttttgtctg tggtttaaag tatggtagtg cgttgctgaa caaaaaaaaa gccgctaacg
    36001 aaaagttagc ggcttgtaaa tgagtttccc tgaattttac gctacggctg ctttcgccgc
    36061 tttgtctgca gcgtcatcct gcgtcatgcg gtgcagtttc ggcgcggtaa acagcatcag
    36121 tactgcaata acggcagtag cgacaccaat ctgcaagaat acgcgaccat agacttccag
    36181 tgacatcagc ggatcggtaa cgttatccgg cacagccatc atacctgcaa cataaccacc
    36241 aatcaggttt gcaccggcag tggtcaggaa ccagctaccc ataatgaagc ccatcagacg
    36301 ctgcggaacg agttgtgcaa ccattgccag acccaggcca gagatcatca gttccccgat
    36361 actctgcagg ccatagctcg cgaccagcca gcttacagac acgataccag cgtcagacgc
    36421 gaatttcgca cccagcggca gaatcaggaa cgcaccagaa cacatcacca tgccgatagc
    36481 aaacttggtt ggcatcggca gggtatcgcc catcttgtta tagatagcgg ccagaatcgg
    36541 gctaccaatg atgatccaga acgggttcag tgcctgatac tgctcaggtt ctacggccag
    36601 gcccagaatg gtgtgttcaa cgttacgaat cgcaaagaag ttcagtgacg ttggcatctg
    36661 gctataaagc acgaagaaga taatggcttc gagcatcagg atgaaggcaa cgatcatttt
    36721 acgacgcgca gcacctttca tcgcgaaggc ttctttaccg aagataacca caataccgaa
    36781 ggcaacaacg cccagcgcca tacgcgcaac ttcctgattg tgcagcagcc aggtggcgat
    36841 agcgatcagt gccacaacac caataatggt cagcagcagg ttacggtagt tgataggctc
    36901 gaagtctggt tttgaaccgt actgtttaac ccaacgttgg cagaaggcga agttaacgat
    36961 agtgatcagc aggcctacaa cgctcaacgc aaacgcaaca ctccagccgt atttcgcggc
    37021 cagccacggc gtagcaatca tagagaagaa agagccgatg ttgacggaca tgtagtacat
    37081 ggtgaatgca ccgtccagac gcgggtcgtt tttctcatag catgtagaaa gcagagaaga
    37141 cgggttagct ttaaacaggc cgttaccgac cgcaatagcc gccataccca tataaacgat
    37201 accggcgtcg tgaccagacc aggcaaccag agcataacca atcgccagca caatagcgcc
    37261 gagcataatt acgcgtttag tacccagtac cttgtcacct aaccagccgc cgatagcgac
    37321 cagaccataa accagggcac taaaggaaga gaaaagggtg attgaatccg cttcagacat
    37381 acccagttgt ttaaccaggt aaacagccat aattccttgt aggccgtaat aaccaaaacg
    37441 ttcccataac tcaatcgaga agatgagata gaacgccttc ggttgtttaa aagcgttcaa
    37501 actgacgctt tcagttggtt tttggtttgc agtggacact tttacctctt tttttacatc
    37561 ccatattaac gggggtgctt tctcgcgtta tgtctaaaaa acatacgcgc aattgttata
    37621 gtgggagggg aaacggcagg taatgttcac tatcttgcac tttcagacaa gtcctttgta
    37681 ataatctgtt acatataact gaggcgggga attcaaccat tccgggaaat gttatccagc
    37741 gttaaatttt tcaaaaaacg taacggcaga ttttttcact accctgagag ggtgatgatg
    37801 gcttaacggc gatatgttct actatttagc gtttttccta gtgagatagt ccagtttctg
    37861 aaaaatagcc agtgtaatgt tttgtaggtc aatatttgtt gtgtgtgtaa atttaaatga
    37921 ttttaacctg attcttgcaa tgtttttaca ttgccacagc atcgtgatct tgatcacgaa
    37981 tgaatagaaa atttcgctat taaaaaaaca attaacctgc atttttggtt atctgcaaac
    38041 ggattacctg atgataacgc taagcaatgg catcattgac gttaaaaaga tgttttaaaa
    38101 gaggataaag aaaggttatg aatggggtaa tcggtgttac ccctgatctt tagatgtcaa
    38161 ctttctcttt gtattcacaa agatcttcaa taatacaaga gccacagcga ggcttgcggg
    38221 caatgcaggt ataacgcccg tgcaggatca accaatggtg gcagtcgact ttaaactctg
    38281 ccggaaccac tttcagtagc ttttcttcta cctgttcgac gtttttcccc ggcgcaaatt
    38341 gagtacgatt gcaaacgcgg aaaatgtgcg tgtcgacagc aatagtcggc cagccgtatg
    38401 cagtgtttaa tacgacgttg gctgttttac gacctacacc aggcagggct tcaagcgcag
    38461 cacgatcttc cggaacctcg ccattatgtt gttccagtaa tatacggcag gttttgatga
    38521 tattttctgc tttgctgtta taaaggccaa tcgttttgat ataggttttc accccttcaa
    38581 cgcccagttc aagcatcgct gcaggcgtat tagccaccgg gtagagtttc gccgtcgcct
    38641 tattaacact gacatcggtc gcctgagcgg aaagcagtac ggcaatcagc aattcaaaag
    38701 gcgaactgaa attaagctcg gtggtgggat gaggattgtt ctcacgcagg cgagtgagga
    38761 tctccaggcg ttttgctttg ttcatcagac attccctgtt tcaccgtttg gcaatgcacg
    38821 ttcggcagct gcttcagtac ggcgcttttt cattttttca tcaatcaggt attttcctgc
    38881 cagcatcagt cccaggccaa taaatgcacc tggtggcagc atcgccagca ggaaagggga
    38941 gtcggtgtgg aaaatctcca cgcgtaatac ttttgcccag ctacctaaca gcgcatctgc
    39001 accgtcaaac aacgtgccat tgccgataat ttcgcgtagt gaacccagca cgaacatggc
    39061 gcaggttgcg cccataccaa ttgaaaagcc gtccagtgcc gaaagcgccg gacctttttt
    39121 ggcggcgaag gcttcagcgc ggcccacaac gatacagtta gtgacaatca gcggaataaa
    39181 aatccctaat gattgataca ggccaaaggc gtaggcgttg atcagcatct gtacagcgct
    39241 gaccaccgag gcgatgatca tcacgtaaat gggaatgcgg atctcggcgg gcgtccagtg
    39301 acgcagcgtc gaaatggtca ggttggttag cgtcagtacc agcgtagtcg caagtcctaa
    39361 acccagagcg ttagtggcag tggacgtgac cgccaacaga ggacaaaggc cgagcagctg
    39421 gaccagcgca gagttgtttt tccacaaccc ctgaacaata acgtctttaa tttcgctcac
    39481 gttttattct ccacaggcag gaagttgaga aagttgtgcc ggtaacgtct gagcgtacaa
    39541 tccggcgcgt tttaccgcat taaccaccgc gcggggagta atcgtcgcgc cagtgaactg
    39601 gtcgaaatca ccaccatctt tcttcaccgc ccagttcgca tcatccgcac cactgatttt
    39661 tttacccgca aaatgggtga tccagtcaga aaggcgcagt tcgattttat cgccaagccc
    39721 tggcgtttcg tggtgctcag tcacgcgcgt gccaagtacc gtgccgttaa aatcggctcc
    39781 caccagcagc tgaatcgcac cggaatagcc atctggcgcg gttgcttcca gaacggcagc
    39841 taccggtttg tcatcctgtt tggcgatgta aacccgatgc tcacctttac ctaactctgg
    39901 cgcagttacc agatagcaac tctgtgccag cgcattgtta tagcgttcag ctggcagcac
    39961 ctgatcaaat aacgcctttt gttgcagact ggcctgctca gcaattgtcg ttttggtcat
    40021 ctggttgatg gccgcagtta accctgttga acccgctgca aagagcgcca acgtaatgcc
    40081 gtgttttcgg atagttttca gcatggttta ccctttgcga tggccgtaga cgcgcggacg
    40141 cgtgtagtaa tcgatcagag gaaccgtgat gttcgccagc aggacggcaa aagccacgcc
    40201 gtcaggatag ccgccgaaac tgcggatcaa ccagactaat aagcccgcca gcgcgccgaa
    40261 aataagacga ccacgattgg tcgtagaagc ggtaaccggg tcagtcaaaa taaagaatgc
    40321 gccgagcatg gtcgcaccag acagcagatg aatttgcggt gctgccagag tatctggtga
    40381 gaacaaccaa cccaacgttg cgcataacgc cagcgttact aagaagctga ggggaatatg
    40441 ccagcgaatc gctttctgcc atagcaacca cacgccgcca gtcagccagg cgagatttac
    40501 ccattgccaa ccagcgcccg ccagaatacc gctgtagatc ggatattgca taatctcttc
    40561 aaccgaatga ccggcacgga cagaggtttt aaatgtatcc agcggtgtcg cctgactaat
    40621 gccatcaata cctaagcgta gcgtgttcat atcaccacca ctggtggtat gtccgctgaa
    40681 aataacctgt atggcgtcga taaaaccagg gatgttgacc gcaatttcat gtggcggtaa
    40741 ccagctggtc atctgcaccg ggaaggagat cagtaagacc acataaccaa tcattgccgg
    40801 attaaacggg ttttgcccca gaccgccata caactgttta gcgatgatca ccgcaaacac
    40861 cgtacccagc acgaccatcc accatggcgc gaggggggga atacttaccg ccagcaataa
    40921 gcctgtcagc aatgctgagt tatctttcaa cgttgcagct accgactgct tgcgtagttt
    40981 gaggacgaga gcttcggcca gaagagcact gaccgacgcc aacaggatct gaacgagagt
    41041 accccaacca aaaaaccaca gttgcgctgc gattcctggc acggctgcga gcaataccaa
    41101 catcataatg cgcgatgtct ggcgctggtt atgggtataa ggggagctag ctattctgaa
    41161 taccatttag tcctcgttta caaccttttg ctgggcggct tttttggcct gaacgcgggc
    41221 aatagccgca gcaactgccg ctttgcgcgg atcaatctgt tcttctggct ctgcattagc
    41281 ctgttgctgt tccagcttgc gtgctttggc acgggcaata gcagcttcga cggcggcttt
    41341 gcgtggatca acctgttctt ctggttccgc attagcctgt tgttgctgtt ccagcttgcg
    41401 cgctttggcg cgtgcaatag ccgcttcgac ggcagctttg cgcggatcga cctgttgttc
    41461 tggctccgca ttggcctgtt gctgttccag cttgcgtgct ttggcgcggg cgatagcggc
    41521 ttcgacggcg gctttgcgtg gatcaacctg ttcttctggt tccgcattag cctgttgttg
    41581 ctgttccagc ttgcgtgctt tggcacgggc aatagcagct tcgacggcgg ctttgcgtgg
    41641 atcaacctgt tcttctggtt ccgcattggc ctgttgctgt tccagcttgc gcgctttggc
    41701 gcgtgcaata gccgcttcga cggcagcttt gcgcggatcg acctgttgtt ctggttcggc
    41761 attagcctgt tgctgttcca gcttgcgtgc tttggcacgg gcaatagcgg cttcgacggc
    41821 ggctttgcgc ggatcaacct gttgttctgg ctccgcattg gcctgttgct gctccagctt
    41881 gcgtgctttg gcgcgggcaa tagccgcttc aacggcagtt ttacgtggat cagcaacggt
    41941 tgcagcgtcg ttagtttgct gcagttctgc ctgtttcgct ctggcttgcg ctttacgggc
    42001 ttcccgtgct gcaataattg cactgttatc cgggcgttcg cccgctttaa tcacaatagg
    42061 ctgtgtagcc tgggcctgtt tctctttcac ccgcgccaga gcggcagcaa tcgcatcttt
    42121 atctttggct gcaggttgaa cggctgcgct cttatgtcgt tcaaggcgag ccgttttttc
    42181 gcgctccaga cgagcctggc gcgcttcgaa acgcgctttg gcttctgcgg cgcgcttttc
    42241 ttcctgacga atagccgcaa tttcagcttt ttcctgacgg aaatattgca ccagggggat
    42301 attgctcggg caaacccacg cgcaagcccc acattcaatg cagtcggcaa tgttatgcgt
    42361 ggtggcttta tcgtgttgct gacctttgct gaaccagtac agctgttgcg gcaaaagatc
    42421 cgcagggcag gcgtcagcac aggcgctaca acggatgcaa ctttgttctt cctgtggttc
    42481 gccaagttca ttggcagagg gagccaaaag acagttggta atctttacga ccgggacatc
    42541 cagccacggt aaggtaaagc ccattagcgg gccgcccata atcaccattt gatcggcaga
    42601 ggggcagaat ccggcatcat tcaataaatg acgcactggc gtacccagcc gtgcccagac
    42661 gttgcccggg cgagcgattg cttcgccagt cagggtcacg acacgctcgg taatcggctc
    42721 gccatcaata acggcacgtt tcactgcata agcggtgccg acgttttgca ttaatacgcc
    42781 gatatcggat gaacgcccgc catgtggaac ctgcttcccg gtcagaatgt aggttaattg
    42841 tttagcaccg ccagaaggat atttggtggg aatcacccgc agagaaatat cgtgggagtc
    42901 cgccagcacc gcgcgtagca tggaaatcgc ctgcggtttg ttatcttcaa tgccgataag
    42961 aatttcgcgc ggctgcagaa tatgcgcaag gatgcggata ccctctacga cctgagccgc
    43021 gcaatcctgc atcaaacggt catcggcggt aatgtacggc tcgcactcag cagcgttgat
    43081 aatcaacgtt tcaatcttat ctccgccgcc ctgcaattta acgcctgtcg gaaatcccgc
    43141 accacccagc ccggcaacac caaactgatg aatgcgctcg attaactctt cgcgactgcg
    43201 agagcgataa tcggcccagc cgtcgcgcgg gatccagcag tcttcgccat cggcatcaat
    43261 aatcacactt aattcagcta aagctgaagg atgagccgta gagtggggcg caatagccgt
    43321 aacggtaccc gaggtgggcg cgtgaaccgg cagcattttg ccgcgaccac gggtaagcgg
    43381 ctggccgcgc aatactttat cgccgacgct aacgcacaac tcaccttcag cgccaatatg
    43441 ttgttttagt ggaatgacaa aacgctgcgc cagtggtacc tggcgcaggg gcgtaccgtt
    43501 ggactgggtt ttcatctccg gtggatggat gccgccgttg aaatcccaga ttttattttt
    43561 tctgaatgca gagaataact taagcatggt gttccacggg aatgatacgc acgggaatgg
    43621 tgttcagatc ccatttccag gagtcaggag tttctgcgac cggttgcaac gagatgcagt
    43681 gcgtcgggca cggatcaaca cataaattgc agcccgtaca gagatcactc attaccgtat
    43741 gcatggcgcg ggtagcgcca acgatggcgt ctaccggaca cgcctgaata catttagtgc
    43801 agccaataca gttattttca tcaataaccg ccaccatccg cgctggcgtt agctcttgcg
    43861 cttcgccatc cagcggctgc ggctcgacat taagcaactc ggcaattttt agcatcacag
    43921 cttcgccacc tggggcgcaa cggttgattt tttcaccgtt acagctgatg gcttccgcgt
    43981 aggggcgaca gccgggataa ccgcactgac cacactggct ctgcggtaag atttcgtcaa
    44041 ttttctcaac gaccggatcg tcttccaccg caaaacggcg ggaggcataa cccagaatgg
    44101 cgccaaacgc cagggccagc aggctcacgg cggcaacggc aatccagata gcattcatta
    44161 caacttcacc aaaccactaa agcccataaa ggccagagac ataagacctg cggtaattaa
    44221 cgcaatggca ttaccgcgaa aaggtgccgg gacatcagcc acagcaaggc gttcgcggat
    44281 ggcggcgaag agcaccatca ccagcgagaa accgacagcg gcggaaaaac cgtacagcgc
    44341 tgactgcaag aaattgtgcc cgagattgat attcagcaac gccacgccga gcacggcaca
    44401 gttggtggtg ataagcggca aaaaaatccc cagcagacgg taaagtaccg ggctggtttt
    44461 gcgcaccacc atttcggtga actgcacaac cacagcaatc accagaataa acgccagggt
    44521 gcgcagataa atcagattaa gtgggatcaa aatccacgta tcgataagcc aggcgcaaat
    44581 agacgccagc gtcattacaa acgttgttgc cagccccatg cccatcgcgg tttccagctt
    44641 tttggaaacc cccataaacg gacagagacc gagaaacttg accagtacaa agttattgac
    44701 cagtacagtt ccgacaaaca gtaacaggta gtcagtcatt tttcggcctg aaataaaaaa
    44761 gccgcctatt atccgttaat ccagagcagg cgacaacagg ttaactgtaa ggttattacg
    44821 gattcacaaa cgtcgctttc acccgcgacg agcgtttgaa ataggggacg atcaatgcgg
    44881 ttgccaacaa agtaaacagc aactggcgaa cggctatgcc atcttctacg ggtgaaaaag
    44941 cgaacgcttt tactgccagc aatacggaaa taagcagcca gataatatag tgtttaggaa
    45001 cacaacgccg acgtttaaag aaagcgatgg tcaaccacag tgtgtaatac cacatggcga
    45061 tagcggtaat aaaagaaacg ccccataaga tttgtgtcgt cagtgcttgt ccgccgagcg
    45121 tttgaaatgt ttgcggagaa gataacgcag cggtatacag caacaacgcc agcgtcgtac
    45181 tcaacagagc gactaaaagc caggccaacg ggccaagcaa ccagcctcca atacgttgtg
    45241 gcgttgtggt ggtcataggt tctccagaat agcgacgcaa acagacaaat ctaattttag
    45301 gggcgttatt ataaggcttt tataaccgat cgctactttc tttactggac atagtgccag
    45361 acggacttcg gtacctggcc gaggtcaaac aaacgcccgc cagaaaccag ctctgcgcga
    45421 cggtgatcgg cagcacgata catattgatc agttcctgat cgtccgtcag ggtgtaatta
    45481 agatggtcgt agagtttttc cagactttcg agtgaactga ttttgcgaaa ttttaataag
    45541 tagtcctgaa cagtcataaa aggtccataa ataattaata ccaaaggggt aggtattatt
    45601 agtgatgata aaatttcacc aaaagtgaac gcttgtgtta ttacaataat aagaatgcgc
    45661 tgatggcaaa tattcaggga tgaaaaactg ctctgaaaag agtaacgcgc tttactatcc
    45721 ctgacaatca tcaacaacat cgaacaagat aataaattcc tggtttaata tccgacaagt
    45781 gaaaacatgc acccggacgg gcagcatgtc gctcaacaag tgcagagctt acttgtgttg
    45841 taccgtagta ctctgttcag gtggctgata gttgtcaatg tgactcgcca cgccaagaag
    45901 aatgactgaa acgacaagaa cgatccaacc tgttaattca ataagacgat tcattacagc
    45961 ccacatctct gttgattgat ccattaactt cagggggtaa atgttactta gcaataatag
    46021 ctccagcaag atttttactg aggtttttgc gatatttagc ttttgtcgtt ggaaaaatcg
    46081 ctattttttt gacttaagtt aaacaacatc ccttattgct ggcaggttat taaactgttg
    46141 agcgagggta aaggatagtg tcaaatagcc atcatacttc aatgagaggc aatgacatga
    46201 gcgactttcc gttagctaaa gcggcgcttg aggcgggtaa acatgtggtc gttgataaac
    46261 cctttaccgt gacactgtca caagcacgag agctggatgc gctggcaaaa accctggggc
    46321 gtgtgttgtc tgtattccat aaccgtcgct gggatagcga ttttctgacc ctaaaaggtt
    46381 tgctcgcgga aggcgtgctg ggggaagttg cttactttga gtctcatttt gaccgcttcc
    46441 gtccgcaggt acgcgatcgt tggcgtgaac agggcggccc aggcagcggt atctggtacg
    46501 atttagcacc gcaccttctt gatcaggcca ttacgctatt tggtttaccg gttagcatga
    46561 cggtagattt ggcacagtta cggcccggag cgcagtcgac cgattatttc cacgctatct
    46621 tgtcctatcc gcagcggcga gtgattttac acggcaccat gctggcagcc gctgagtcag
    46681 cacggtatat cgtgcatgga tcccgaggca gttatgtgaa atatggcctc gatccacagg
    46741 aagaacgtct gaaaaatggc gagcgtctgc cgcaggaaga ctggggctac gatatgcgtg
    46801 atggcgtact tacccgcgtg gaaggtgagg aacgtgtcga agaaacgctg ttgacagtgc
    46861 cggggaatta tccggcttac tatgcggcta ttcgtgatgc gttaaatggc gatggtgaaa
    46921 atccggttcc ggcaagtcag gcaatccagg taatggagtt gattgagctg ggcatcgaat
    46981 ccgccaaaca tcgcgcgact ttgtgccttg cgtgaaaagg ggatggtgca attagcacca
    47041 tccatttttg ttacttcgcg gcgacttttt ctcgcagtgc gcgtttttcc tctgcgctga
    47101 ggaaagccat ttccagacca ttaatctgtg cctggcggat ttgctcgcgg gataacccag
    47161 cagctggcgc ggcaacggta tattcgtgaa tgatatccac tccctgcacg ccgggatcgt
    47221 cagtgttaat gctggcacga atgccatgct caaggaacgt tttcagcgga tgtgcagcca
    47281 gatccgccac ggtgctggtc tgaatattgg aggtcagaca ggattcaata ccaatttgtt
    47341 gctcggcgag aaaatccatc agcgcccgat cttcaatggc ttttacgcca tgtccaatac
    47401 gctccgcccc cagttcacga atcgcctgcc agatgctttc cggtccggca gcttcgcctg
    47461 catggacggt aatatgccag cccgcatcac gcgcgcggtt gaaatgagaa aggaacagac
    47521 ttcccgggaa accaagttca tcaccggcta aatcaagtgc ggtaatctgg tcacggtggg
    47581 ctaaaaaggc ctccagctct tgctgacagg cggcttcgcc gaaggtccgg ctcataatac
    47641 cgataagctt cgcctgcaca ccaaaggtgc ggcaaccttc acgtacgcca tcgatcaccg
    47701 cttcgacaac acccgctaca ggcagctgat gtgccattgc catgtagcct ggtgaaaaac
    47761 gcagttcgac atagtgcagg ccgttacggg ctgcatcttc aatgttttca aatgccacgc
    47821 ggcggcaggc atcaagagag gcgagaactt taacgcccca gtcaagttta gtcagaaagc
    47881 tcaccagatc gggttcgttg gcaatgacct gaacgtgggg agtcagtgtt tccagggatt
    47941 gtgcaggaag cgagatatta tactggcggc caagttcaag aatggtctgg ggacgaatgt
    48001 tgccatcaag gtggcgatgg atatcagtta atggcagggt ggtatcaatc atggtcgcac
    48061 tctttttctg gatataaaag tgcgcaccat tataaaaaca aagcagggta aaaatccacg
    48121 attgcgcaac gattttttac gttgcgcaat tggggttaac caacagcgcg gatggcgtta
    48181 attaatccag ccacaccttt ttccagtttc gaacgtgggc agccggcatt gagtcggaca
    48241 aaaccacgac cttcttcacc gtaggtatat cccggcatga tcgcgatctt ttcttgctcg
    48301 ataagcgctt tttgcaacgc gttgtcgtca atattcaacg gacgtagatc aagccaggcc
    48361 agataagtgg attgcgggat ctgccagttg agttcaggaa acgcagcgtt cattttatct
    48421 gcgatatacg tcaggttatc tttcagatag acgcgtaagg catccagcca tggcgcgcct
    48481 tgctgatagg cggcgatatg agcagttaac gccagtaccg aaggggaaga aagcccatca
    48541 cgtcctttca gtgccgataa ataggcatcg cggctactgc tattttctat aatcccgtaa
    48601 gcaccggtca gggcgggaat attgaaactt tttgatcccg acgttagcaa cgcccagtct
    48661 ccgcgcgcca cattactcca gggaatatgc ggctgctcgc cccaaaccat atccatatgg
    48721 atttcatcgg aaataacccg cacaccatga cgctcgcaca ggtcagccat gatctccagc
    48781 tcatcgcacg tccacacttt cccggtagga ttctgtgggc tacacaggag cataatttta
    48841 cattctggtt tcgccagcac ggcttccagc ttgcccatat cgcaaaacca gccgtcagcc
    48901 tgcttctcta aagcaacggg cattactgtg cgctggttac cttcaatggc cttgtaaaat
    48961 gcgtcatagg cgggtgtgtg gatcaccacg ccttcacctg tttcagacca ctgacgaatc
    49021 agttctgaaa ccatatagat aacagaaggg ccatacacca ccgactgagg atcgatggcg
    49081 gtgtaatgct gggtggaaaa ccagtgggca atagccgcga gaaactcatc gtttttccag
    49141 cggctgtagc caaacacgcc gtgtatcagg cgctgattca gcgcctcgat aatgcagggg
    49201 gcagtggcaa aatccatgtc tgaaatcgtg aacggtaaca ggtcagcagt gccgaaacgg
    49261 tcagcgacat aatcccactg cgtacaccat gtgccatgac gatccacgac ctttgaaaaa
    49321 tcgaacatat cttatcctta tgcctggaca gtacgcatca gaccgaccat ttcatctttt
    49381 actgactgaa cttgtggccc gataacaacc tgcaggttat gttgattaag ttgtactacg
    49441 ccaattgccc gattgtcctt cagtgcctgc acattaacaa gcgacatatc ttttacagac
    49501 aaacgcagac gcgtaatgca gttatcgaga ctgacaatat tgtcggcacc gcctaaggct
    49561 tcgaggattg ccggaacgtt gtaacctgat ttacccggcg caccggcaac ggctttttcg
    49621 attgaactgg caacttcact atcgcgcccc ggggttttga gattgaagcg ggtgatagcg
    49681 aaacggaaga tgatgtagta aacgacaaac cagattgccg ccactactgg caccatgtac
    49741 cacttggttg acagaccatg caaaataccg aacaccacaa agtcgatgat attgccgtcg
    49801 gtattaccga tggtgacgcc gagcacagac atgacagtga agccgaggcc ggttaacagc
    49861 gcgtggatga catacagaac tggcgctacg aacaggaaca ggaattccag aggttcggtc
    49921 gtgccgccaa cgacacaggc gatcaggcca gaaatcagca gacctttaat tttatggcga
    49981 ttttccgggc gcgcacagtg atacatagct aacgctgcac ctggcagacc gccgagaaac
    50041 gcaggcattt taccttgcga aaggaaacgc gtggcgcttt cagaaaaacc gtgagtggtc
    50101 gggcaactca attgcgcctg gaagatggtc agtgcaccgc tgacggtttg accgcagact
    50161 tcctgcgtgc cgcctgcgtc ggtaaagcga attaatgcca ccagaatgtg atgcagacca
    50221 aacggcaaca gcagacgttc accggtacca aacagcatcg gtccgaaatc acccgcgctg
    50281 ttgatcatat ggcctaagcc gctaataccc atggcgaaaa tcggccagac taatggaatc
    50341 accaggccga caagacccat caccagcgag gagatgattg gtacgaagcg cgtaccgccg
    50401 aagaatgcca gcgcatccgg caggcggata ttatggaatc gctcatgcag catccagacg
    50461 ataataccgg cgatcaccgc accgaggatc ccggtgtcga tcgactggat cccaagaatg
    50521 ctctggatgt tattggcttt cagaacggcg gcgtccatgg ttggcagaat gcctttattg
    50581 gtcaaccaga agtttaccgc gaggttcatt accgcataac cgacgaagcc agcgaatgcc
    50641 gctacgcctt tgttttcgcg tgccagaccc agcgggatgg cgatacagaa catgactggc
    50701 aggaaactaa aagcaaacga gccaatctta ctcatccagg taaagatagc ctgcaacacg
    50761 gggttgccca ggaccgggat cagggtgatg acatcatggc tgctaagaga actaccaatg
    50821 ccgagcataa tgccgcagaa cgacaataat gccacgggta acatgaaggt tttgcctaac
    50881 tgctggaaga actcccacag cgtgactttc ggtgctgttt tcgccgtcat aaaacgactc
    50941 ctcgtagaga acaatctgga ttcagtaaat tgcgcgagaa gataaaacgt tttatcaaat
    51001 tttagtgagg cataaatcac attacgcaac gataatagcg ggtataagat aaataaaagg
    51061 taaaacgttt tatctgtcac ataatcaggg agtaggtcat ctgcatggct accgccaaaa
    51121 aaataaccat tcatgatgtt gcgctggctg cgggcgtgtc ggtaagtacc gtttcgctgg
    51181 tgcttagtgg caaagggcga atctctaccg ccacaggaga acgcgttaac gccgccattg
    51241 aagagctggg atttgtgcgc aatcggcagg cgtcggcgct gcgcggcggg caaagtggcg
    51301 tcattggttt gatcgtccgt gatttatctg cgccgtttta cgccgaattg acggccggat
    51361 tgacggaagc tctggaagcg cagggacgga tggttttttt gcttcacggc ggtaaagacg
    51421 gcgagcagct ggcacagcgg ttttcactat tactgaatca gggtgtcgat ggtgtggtaa
    51481 ttgccggggc tgcaggaagc agcgatgacc tgcgacggat agcagaagaa aaagctatcc
    51541 cggtgatttt cgcttcccgt gccagttatc ttgatgacgt tgatacggtt cgcccggaca
    51601 acatgcaggc tgcacagttg ttgacggagc atctcattcg caatgggcat cagcgtatcg
    51661 cctggctggg agggcaaagt tcctcattaa cccgggcaga acgggtgggg ggctattgtg
    51721 cgactctact aaaatttggc ctgccgtttc acagcgattg ggtgctggag tgcacttcca
    51781 gccagaagca agccgcggaa gctatcacgg cgcttttacg tcataacccg accatcagcg
    51841 ccgtggtttg ctataacgaa actattgcga tgggggcatg gtttggtttg ctgaaagcag
    51901 gaaggcaaag cggggaaagc ggagtcgatc gttactttga gcaacaggtt tcgctggcgg
    51961 catttaccga tgcaacgcct accacacttg atgatatacc cgttatctgg gccagcacgc
    52021 cagcgcggga acttggtacc acacttgcgg atcgcatgat gcaaaaaatc acccatgaag
    52081 agacgcattc acgcaatctt attattcccg cccggctcat tgcggcgaaa taatcctctc
    52141 tttatctgct atacctggta gtgtcctttc ctcaaggtta atgataaaaa atgtggcaca
    52201 caggcggtgc cttttatttt tactgaagtt cacaggaggt ttatgtgttt aattctgaca
    52261 acctgagact cgacggaaaa tgcgccatca ttacaggtgc gggtgcaggt attggtaaag
    52321 aaatcgccat tacattcgcg acagctggcg catctgtggt ggtcagtgat attaacgccg
    52381 atgcagctaa tcatgttgta gatgaaattc aacaactggg tggtcaggca tttgcctgcc
    52441 gctgcgatat tacttccgaa caggaactct ctgcactggc agactttgcc gtcagtaagt
    52501 tgggtaaagt tgatatcctg gttaacaacg ccggtggcgg tgggcctaaa ccgtttgata
    52561 tgccaatggc agattttcgc cgcgcttatg aactgaatgt attttctttt ttccatctgt
    52621 cacaacttat tgcgccagaa atggaaaaaa atggcggtgg cgttattctg accattactt
    52681 ctatggcggc agaaaataaa aatataaaca tgacctccta tgcatcatct aaagctgcgg
    52741 ccagtcatct ggtcagaaat atggcgtttg acctgggtga aaaaaatatt cgggtgaatg
    52801 gcattgcgcc gggggcaata ttaaccaatg ccctgaaatc cgttattacc ccagaaattg
    52861 aacagaaaat gttgcaacac acaccaatca gacgtctggg ccaaccgcaa gatattgcta
    52921 acgcggcgct gttcctttgt tcgcctgcag ccagctgggt aagcggacaa attctcaccg
    52981 tctccggtga tggggtacag gaactcaatt aatacactaa cgaaccggta aacagccgta
    53041 tgtgttgttt accgggatag cgtgtgcaac tcgtcaacgt ctctgctaaa caactggcag
    53101 ccaaatcacg gctattggtt aaccaatatc tggataaaaa gcttacgaat tgagtgtgcc
    53161 ttcgcactat tcaacagcaa tgataggcgc tcacctgaca acgcggtaaa ctagttattc
    53221 atgctaacta taatggttta atgatggata acatgcagac tgaagcacaa ccgacacgga
    53281 cccggatcct caatgctgcc agagagattt tttcagaaaa tggatttcac agtgcctcga
    53341 tgaaagccat ctgtaaatcc tgcgccatta gtcccgggac gctctatcac catttcatct
    53401 ccaaagaagc cttgattcag gcgattatct tacaggacca ggagagggcg ctggcccgtt
    53461 tccgggaacc gattgaaggg attcatttcg ttgactatat ggtcgagtct attgtctctc
    53521 tcacccatga agcctttggg caacgagcgc tggtggtcga aattatggcg gaagggatgc
    53581 gtaacccaca ggtcgccgcc atgcttaaaa ataagcatat gacgatcacg gaatttgttg
    53641 cccagcggat gcgtgatgcc cagcaaaaag gcgagataag cccagacatc aacacggcaa
    53701 tgacttcacg tttactgctg gatctgacct acggtgtact ggccgatatc gaagcggaag
    53761 atctggcgcg tgaagcgtcg tttgctcagg gattacgcgc gatgattggc ggtatattaa
    53821 ccgcatcctg atcctctctc tctttccgcg ggctggtgac aactgagccc gcgtttcata
    53881 tcgtaatttc tctgtgcaaa aatcatcctc ccagggatcg gagaattcca cctaaatatt
    53941 catcgtagca atatatcatg agggtttatc gttcccaata tgttcgaatg aacgttcgat
    54001 tgcttatttt gtggcttctg tcaacgctgt tttaaagatt aatgcgatca atatcacgct
    54061 gtgggtattg cagtttttgg ttttttgatc gcggtgtcag ttctttttat ttccatttct
    54121 cttccatggg tttctcacag ataactgtgt gcaacacgga attggttaac taatcagatt
    54181 aaaggttgac cagtattttt atcttaatga ggagtccctt atgttacgtc ctgtagaaac
    54241 cccaacccgt gaaatcaaaa aactcgacgg cctgtgggca ttcagtctgg atcgcgaaaa
    54301 ctgtggaatt gatcagcatt ggtgggaaag cgcgttacaa gaaagccggg caattgctgt
    54361 gccgggcagt tttaacgatc agttcgccga tgcagatatt cgtaattatg tgggcaacgt
    54421 ctggtatcag cgcgaagttt ttataccgaa aggttgggcg ggccagcgta ttgtactgcg
    54481 tttcgatgcg gtcactcatt acggcaaagt gtgggtaaat aatcaggaag tgatggagca
    54541 tcagggcggc tatacgccat ttgaagccga tgtcacaccg tatgttattg ccgggaaaag
    54601 tgtacgtatc actgtttgtg tgaacaacga actgaactgg cagactatcc cgccgggaat
    54661 ggtgattacc gacgaaaacg gcaagaaaaa gcagtcttac tttcatgatt tctttaacta
    54721 cgccgggatc catcgcagcg taatgctcta caccacgccg aacacctggg tggacgatat
    54781 caccgtggtg acgcatgtcg cgcaagactg taaccacgca tctgttgact ggcaggtggt
    54841 ggcaaatggt gatgtcagcg ttgaactgcg tgatgcggat caacaggtgg ttgcaactgg
    54901 acaaggcacc agcgggactt tgcaagtagt gaatccgcac ctctggcaac cgggtgaagg
    54961 ttatctctat gaactgtgcg tcacagccaa aagccagaca gagtgtgata tctacctgct
    55021 gcgcgtcggt atccggtcag tggcagtgaa gggcgaacag ttcctgatca accacaaacc
    55081 gttctacttt actggctttg gtcgtcatga agatgcggat ttgcgcggca aaggattcga
    55141 taacgtgctg atggtgcacg atcacgcact aatggactgg attggggcca actcctaccg
    55201 tacctcgcat tacccttacg ctgaagagat gctcgactgg gcagatgaac atggaatcgt
    55261 ggtgattgat gaaactgcag ctgtcggctt taacctctct ttaggcattg gtttcgaagc
    55321 gggcaacaag ccgaaagaac tgtacagcga agaggcagtc aacggggaaa cccagcaggc
    55381 gcacttacag gcgattaaag agctgattgc gcgtgacaaa aaccacccaa gcgtggtgat
    55441 gtggagtatt gccaacgaac cggatacccg tccgcaaggt gcacgggaat attttgcgcc
    55501 actggcggaa gcaacgcgta aactcgaccc gacgcgtccg atcacctgtg tcaatgtaat
    55561 gttctgcgac gctcacaccg ataccatcag cgatctcttt gatgtgctgt gcctgaaccg
    55621 ttattacggt tggtatgtcc aaagcggcga tttggaaacg gcagagaagg tactggaaaa
    55681 agaacttctg gcctggcagg agaaactgca tcagccgatt atcatcaccg aatacggtgt
    55741 ggatacgtta gccggcctgc actcaatgta caccgacatg tggagtgaag agtatcagtg
    55801 tgcatggctg gatatgtatc accgcgtctt tgatcgcgtc agcgctgtcg tcggtgagca
    55861 ggtatggaat ttcgccgatt ttgcgacctc gcaaggcata ttgcgcgttg gcggtaacaa
    55921 gaaagggatc ttcactcgcg accgcaaacc gaagtcggcg gcttttctgc tgcaaaaacg
    55981 ctggaccggc atgaacttcg gtgaaaaacc gcagcaggga ggcaaacaat gaatcaacaa
    56041 ctctcctggc gcgccatcgt cggctacagc ctcggtgacg tcgccaataa cttcgccttc
    56101 gcaatggggg cgctcttcct gttgagttac tacaccgacg tcgctggcgt cggtgccgct
    56161 gcggcgggca ccatgctgtt actggtgcgg gtattcgatg ccttcgccga tgtctttgcc
    56221 ggacgagtgg tggacagtgt gaatacccga tggggaaaat tccgcccgtt tttactcttc
    56281 ggtactgcgc cgttaatgat cttcagcgtg ctggtattct gggtgccgac cgactggagc
    56341 catagcagca aagttgtgta tgcatatttg acctacatgg gactcgggct ttgctacagc
    56401 ctggtgaata ttccttatgg ttcacttgct accgcgatga cccaacaacc acaatcccgc
    56461 gcccgtctgg gcgcggctcg cgggattgcg cttcattgac ctttgtctgc ctggcatttc
    56521 tgataggacc gagcattaag aattccagcc cggaagagat ggtgtcggta tatcatttct
    56581 ggacaattgt gctggcgatt gccggaatgg tgctttactt catctgcttc aaatcgacgc
    56641 gtgagaatgt ggtacgtatc gtggcgcagc cgtcattgaa gatcagtctg caaaccctga
    56701 aacggaatcg cccgctgttt atgttgtgca tcggtgcgct gtgtgtgctg atttcgacct
    56761 tcgcggtcag cgcctcgtcg ttgttctacg tgcgctatgt gttaaatgat accgggctgt
    56821 tcactgtgct ggtactggtg caaaacctgg tcggtactgt ggcatcggca ccgctggtgc
    56881 cggggatggt cgcgaggatc ggtaaaaaga ataccttcct gattggcgct ttgctgggaa
    56941 cctgcggtta tctgctgttc ttctgggttt ccgtctggtc actgccggtg gcgttggttg
    57001 cgttggccat cgcatcaatt ggccagggcg ttaccatgac cgtgatgtgg gcactggaag
    57061 ctgataccgt agaatacggt gaatacctga ccggcgtgcg aattgaaggg ctcacctatt
    57121 cactattctc atttacccgt aaatgcggtc aggcaatcgg aggttcaatt cctgccttta
    57181 ttttgggatt aagcggatat atcgccaatc aggcgcaaac gccggaagtt attacgggca
    57241 tccgcacatc aattgcctta gtaccttgcg gatttatgct actggcattc gtcattatct
    57301 ggttttatcc gctcacggat aaaaaattca aagaaatcgt tgttgaaatt gataatcgta
    57361 aaaaagtgca gcagcaatta atcaacgata tcactagtta atattcaata aaaataatca
    57421 gaac
//
LOCUS       DAFGPF010000018        53879 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFGPF010000018 DAFGPF010000000
VERSION     DAFGPF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 53879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53879
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.018"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            25..438
                     /locus_tag="LSX49_001305"
     CDS             25..438
                     /locus_tag="LSX49_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBL7167737.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQQGYGTLADVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(483..800)
                     /gene="hspQ"
                     /locus_tag="LSX49_001306"
     CDS             complement(483..800)
                     /gene="hspQ"
                     /locus_tag="LSX49_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HBL7167738.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(858..2048)
                     /gene="rlmI"
                     /locus_tag="LSX49_001307"
     CDS             complement(858..2048)
                     /gene="rlmI"
                     /locus_tag="LSX49_001307"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HBL7167739.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFTRRLQQAQKWRDWLAQKDGLDSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVA
                     VRKKEGMELTQGPITGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGV
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            2143..2421
                     /gene="yccX"
                     /locus_tag="LSX49_001308"
     CDS             2143..2421
                     /gene="yccX"
                     /locus_tag="LSX49_001308"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBL7167740.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKKLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR"
     gene            complement(2418..2747)
                     /gene="tusE"
                     /locus_tag="LSX49_001309"
     CDS             complement(2418..2747)
                     /gene="tusE"
                     /locus_tag="LSX49_001309"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HBL7167741.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGITLSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(2839..3498)
                     /gene="yccA"
                     /locus_tag="LSX49_001310"
     CDS             complement(2839..3498)
                     /gene="yccA"
                     /locus_tag="LSX49_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HBL7167742.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(3707..3794)
                     /locus_tag="LSX49_001311"
     tRNA            complement(3707..3794)
                     /locus_tag="LSX49_001311"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3758..3760),aa:Ser,seq:tga)
     gene            4222..5340
                     /gene="hyaA"
                     /locus_tag="LSX49_001312"
     CDS             4222..5340
                     /gene="hyaA"
                     /locus_tag="LSX49_001312"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HBL7167743.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIIAQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            5337..7130
                     /gene="hyaB"
                     /locus_tag="LSX49_001313"
     CDS             5337..7130
                     /gene="hyaB"
                     /locus_tag="LSX49_001313"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HBL7167744.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQLIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALKLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            7149..7856
                     /gene="hyaC"
                     /locus_tag="LSX49_001314"
     CDS             7149..7856
                     /gene="hyaC"
                     /locus_tag="LSX49_001314"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HBL7167745.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMIFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            7853..8440
                     /locus_tag="LSX49_001315"
     CDS             7853..8440
                     /locus_tag="LSX49_001315"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HBL7167746.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEDVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
                     QPANESRCLNYDCLSMENYEGIRLRQYRMTLEEQG"
     gene            8437..8835
                     /gene="hyaE"
                     /locus_tag="LSX49_001316"
     CDS             8437..8835
                     /gene="hyaE"
                     /locus_tag="LSX49_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HBL7167747.1"
                     /translation="MSNDTPFDALWQRMLARGWTPISESRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTCGN
                     YRGVLNGIHPWAELINLMRGLVEPQQERAS"
     gene            8832..9689
                     /locus_tag="LSX49_001317"
     CDS             8832..9689
                     /locus_tag="LSX49_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HBL7167748.1"
                     /translation="MSETFFHLLGPGTQLNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSERQPPLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQA
                     DGSESEIQEAIFCGLWRVRRRHGEQLLEDKLEAGCAPLALWQAATQNVLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     QWLAEGAPT"
     gene            9823..11367
                     /gene="appC"
                     /locus_tag="LSX49_001318"
     CDS             9823..11367
                     /gene="appC"
                     /locus_tag="LSX49_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HBL7167749.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFAIKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRELEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            11379..12515
                     /gene="appB"
                     /locus_tag="LSX49_001319"
     CDS             11379..12515
                     /gene="appB"
                     /locus_tag="LSX49_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HBL7167750.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARNDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            12528..12620
                     /gene="cbdX"
                     /locus_tag="LSX49_001320"
     CDS             12528..12620
                     /gene="cbdX"
                     /locus_tag="LSX49_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HBL7167751.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            12700..14010
                     /gene="appA"
                     /locus_tag="LSX49_001321"
     CDS             12700..14010
                     /gene="appA"
                     /locus_tag="LSX49_001321"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001623747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acid phosphatase/4-phytase"
                     /protein_id="HBL7167752.1"
                     /translation="MKAILIPFLSLLIPLTPKSAFAQSEPELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKEGCPQP
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLNREKQDESCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIMTALAPHPPQKQVYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEVRIPACALHQDK"
     gene            complement(13998..14210)
                     /gene="cspH"
                     /locus_tag="LSX49_001322"
     CDS             complement(13998..14210)
                     /gene="cspH"
                     /locus_tag="LSX49_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HBL7167753.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            14496..14708
                     /gene="cspG"
                     /locus_tag="LSX49_001323"
     CDS             14496..14708
                     /gene="cspG"
                     /locus_tag="LSX49_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HBL7167754.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            14719..14907
                     /locus_tag="LSX49_001324"
     CDS             14719..14907
                     /locus_tag="LSX49_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL7167755.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTDHAPLDFTK"
     gene            14882..15112
                     /gene="ymcE"
                     /locus_tag="LSX49_001325"
     CDS             14882..15112
                     /gene="ymcE"
                     /locus_tag="LSX49_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HBL7167756.1"
                     /translation="MRRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFGEM
                     AYNISYLTRVPGTNTLLACCCLLRPEEVNSEY"
     gene            15102..15275
                     /locus_tag="LSX49_001326"
     CDS             15102..15275
                     /locus_tag="LSX49_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HBL7167757.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(15324..16397)
                     /locus_tag="LSX49_001327"
     CDS             complement(15324..16397)
                     /locus_tag="LSX49_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL7167758.1"
                     /translation="MAEKKRTRWQRRPGTTGGKLPWNDWRNATTWRKATQLLLLAINI
                     YIAITFWYWVRYYETAGSTTFVTRPGGIEGWLPIAGLMNLKYSLATGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQFVLPRWLDIPLRGVKYL
                     LLSFFLYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISMIVLLIASLFI
                     RHAWCRYLCPYGALMGVVSLLSPFKIRRNAESCIDCGKCAKSCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLAFSLQKPAANKKAFALSGWLMTLLVMGIMFAAIGYAMYAG
                     VWQSPVPEELYQRLIPQSPMIGH"
     gene            complement(16480..19212)
                     /gene="torS"
                     /locus_tag="LSX49_001328"
     CDS             complement(16480..19212)
                     /gene="torS"
                     /locus_tag="LSX49_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HBL7167759.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGQRLQLRQQQQQLSQQIVAAADEIARLAQGQAN
                     NAATSAGATQAGIYDLIEQHQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAPTLEKQLNNAVKILQRRQIRIEDPGVRTQVATTLTTVSQYSDLLALY
                     QQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGLVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIG
                     RLMDAFRSSVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATEIADDVPTALMGDPRRIRQVI
                     TNLLSNALRFTDEGHIILRSRIDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRVPLRVATAPVPKTVNQAVRLDGL
                     RLLLIEDNPLTQRITVEMLNSSGAQVVAVGNAAQALETLQNSEPFAAALVDFDLPDID
                     GITLARQLAQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQVNNDQPLDVSQLNEDAHLMGAEKIHEWLILFKQHALPLLDEIDIARASQDNEKIK
                     RAAHQLKSSCSSLGMRSASQQCAQLEQQPLSAPLPHEEITRSVAALEAWLIRKT"
     gene            19295..20323
                     /gene="torT"
                     /locus_tag="LSX49_001329"
     CDS             19295..20323
                     /gene="torT"
                     /locus_tag="LSX49_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HBL7167760.1"
                     /translation="MRVLLFLLLSLFMLSAFSADNLLRWHDAQHFTVQASTPLKAKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVANLPVIELVNAIDAPHVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVMTPKNADREHIRRSLSPGGFRPVYFY
                     QHTSAAKK"
     gene            complement(20296..20988)
                     /gene="torR"
                     /locus_tag="LSX49_001330"
     CDS             complement(20296..20988)
                     /gene="torR"
                     /locus_tag="LSX49_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HBL7167761.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            21118..22290
                     /gene="torC"
                     /locus_tag="LSX49_001331"
     CDS             21118..22290
                     /gene="torC"
                     /locus_tag="LSX49_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HBL7167762.1"
                     /translation="MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            22290..24836
                     /gene="torA"
                     /locus_tag="LSX49_001332"
     CDS             22290..24836
                     /gene="torA"
                     /locus_tag="LSX49_001332"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HBL7167763.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     EAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYEQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFISPQDASARGIRHGDV
                     VRVFNVRGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            24833..25432
                     /gene="torD"
                     /locus_tag="LSX49_001333"
     CDS             24833..25432
                     /gene="torD"
                     /locus_tag="LSX49_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HBL7167764.1"
                     /translation="MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLTAAVNGLENSIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLDLLSHLHFSLGEGTVPARRIDGLRQKTLTA
                     LREWLPEFAARCRQYDSFGFYAALSQLLLVLVECDYQKR"
     gene            complement(25687..25992)
                     /gene="cbpM"
                     /locus_tag="LSX49_001334"
     CDS             complement(25687..25992)
                     /gene="cbpM"
                     /locus_tag="LSX49_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HBL7167765.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPSEIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP"
     gene            complement(25992..26912)
                     /gene="cbpA"
                     /locus_tag="LSX49_001335"
     CDS             complement(25992..26912)
                     /gene="cbpA"
                     /locus_tag="LSX49_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HBL7167766.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIF
                     GQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVS
                     PWEAALGTKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
     gene            27447..28688
                     /gene="agp"
                     /locus_tag="LSX49_001336"
     CDS             27447..28688
                     /gene="agp"
                     /locus_tag="LSX49_001336"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HBL7167767.1"
                     /translation="MNKTLIAATVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYKLLEQIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTERTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDANGFCPMDKFDRVLNEAVK"
     gene            complement(28726..28953)
                     /locus_tag="LSX49_001337"
     CDS             complement(28726..28953)
                     /locus_tag="LSX49_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HBL7167768.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(28974..29570)
                     /gene="wrbA"
                     /locus_tag="LSX49_001338"
     CDS             complement(28974..29570)
                     /gene="wrbA"
                     /locus_tag="LSX49_001338"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HBL7167769.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            29943..30116
                     /locus_tag="LSX49_001339"
     CDS             29943..30116
                     /locus_tag="LSX49_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HBL7167770.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            complement(30199..31527)
                     /gene="rutG"
                     /locus_tag="LSX49_001340"
     CDS             complement(30199..31527)
                     /gene="rutG"
                     /locus_tag="LSX49_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HBL7167771.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKNVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGITTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNSVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQKP"
     gene            complement(31548..32042)
                     /gene="rutF"
                     /locus_tag="LSX49_001341"
     CDS             complement(31548..32042)
                     /gene="rutF"
                     /locus_tag="LSX49_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309280.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization flavin reductase protein
                     F"
                     /protein_id="HBL7167772.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEKALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALM
                     RPAC"
     gene            complement(32053..32643)
                     /locus_tag="LSX49_001342"
     CDS             complement(32053..32643)
                     /locus_tag="LSX49_001342"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HBL7167773.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWREPPVSDETLREIYALMKWGP
                     TSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFP
                     HGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFA
                     GSTLKSDLLINIGYGDSSKLFARLPRLSFEEACGLL"
     gene            complement(32653..33453)
                     /gene="rutD"
                     /locus_tag="LSX49_001343"
     CDS             complement(32653..33453)
                     /gene="rutD"
                     /locus_tag="LSX49_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HBL7167774.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLDQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYP
                     ASVTVLVSVNGWLRINTHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSS
                     ELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            complement(33461..33847)
                     /gene="rutC"
                     /locus_tag="LSX49_001344"
     CDS             complement(33461..33847)
                     /gene="rutC"
                     /locus_tag="LSX49_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein C"
                     /protein_id="HBL7167775.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            complement(33859..34551)
                     /gene="rutB"
                     /locus_tag="LSX49_001345"
     CDS             complement(33859..34551)
                     /gene="rutB"
                     /locus_tag="LSX49_001345"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HBL7167776.1"
                     /translation="MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFC
                     DALSSTSFARIA"
     gene            complement(34551..35642)
                     /gene="rutA"
                     /locus_tag="LSX49_001346"
     CDS             complement(34551..35642)
                     /gene="rutA"
                     /locus_tag="LSX49_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HBL7167777.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKS
                     DFKGDFFTMDDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVANVPGAEGVLLTFDDF
                     LSGIETFGERIQPLMQCRAHLPALTQEVA"
     gene            35930..36568
                     /gene="rutR"
                     /locus_tag="LSX49_001347"
     CDS             35930..36568
                     /gene="rutR"
                     /locus_tag="LSX49_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HBL7167778.1"
                     /translation="MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR"
     gene            complement(36608..40570)
                     /gene="putA"
                     /locus_tag="LSX49_001348"
     CDS             complement(36608..40570)
                     /gene="putA"
                     /locus_tag="LSX49_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HBL7167779.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQSLPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPR
                     EVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVIDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRQVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDNALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            40625..40834
                     /locus_tag="LSX49_001349"
     CDS             40625..40834
                     /locus_tag="LSX49_001349"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167780.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLINEIDMTGIKKITQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            40993..42501
                     /gene="putP"
                     /locus_tag="LSX49_001350"
     CDS             40993..42501
                     /gene="putP"
                     /locus_tag="LSX49_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HBL7167781.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNGHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKQASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQEG"
     gene            42721..43551
                     /locus_tag="LSX49_001351"
     CDS             42721..43551
                     /locus_tag="LSX49_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000497947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family protein"
                     /protein_id="HBL7167782.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGVWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFVLPPRAGATASRSV
                     "
     gene            43609..44736
                     /gene="efeO"
                     /locus_tag="LSX49_001352"
     CDS             43609..44736
                     /gene="efeO"
                     /locus_tag="LSX49_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HBL7167783.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAADIPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDKYADQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKY
                     RTKEGFENYDKLTDADRNALKGPITALAEDLAQLRGVLGLD"
     gene            44742..46013
                     /gene="efeB"
                     /locus_tag="LSX49_001353"
     CDS             44742..46013
                     /gene="efeB"
                     /locus_tag="LSX49_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HBL7167784.1"
                     /translation="MQYEDENGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNAKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYLGSALLRV"
     gene            46640..47428
                     /gene="phoH"
                     /locus_tag="LSX49_001354"
     CDS             46640..47428
                     /gene="phoH"
                     /locus_tag="LSX49_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HBL7167785.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMSGVEA
                     IGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVRSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS"
     gene            complement(47478..47891)
                     /gene="pgaD"
                     /locus_tag="LSX49_001355"
     CDS             complement(47478..47891)
                     /gene="pgaD"
                     /locus_tag="LSX49_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HBL7167786.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAIDLLTGY
                     FWQSEARSRLQFYFLLAVVNAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKTLVRV"
     gene            complement(47893..49218)
                     /gene="pgaC"
                     /locus_tag="LSX49_001356"
     CDS             complement(47893..49218)
                     /gene="pgaC"
                     /locus_tag="LSX49_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HBL7167787.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIIGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPRLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWNQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAAQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLVIENRYEHNLA
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            complement(49211..51229)
                     /gene="pgaB"
                     /locus_tag="LSX49_001357"
     CDS             complement(49211..51229)
                     /gene="pgaB"
                     /locus_tag="LSX49_001357"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HBL7167788.1"
                     /translation="MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVVISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDEMVS
                     REYFATWQQVREVARSRLVEVASHTWDSHYGIQANATGSLLPAYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKAEVNPHVFVWPYGEANGIAIAELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKPLQRVMHIDLDYVYDENRQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYRRLSPFDDRVRAQVGMLY
                     DDLAGHAAFDGILFHDDALLSDYEDASAAAIAAYQQAGFSGSLSEIRQNPEQFKQWTR
                     FKSRALADFTLELSARVKAIRGPHVKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYMEGVTEKSADQWLIQLTNQMKSIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDVIRPEFSTAWYPKND"
     gene            complement(51238..53661)
                     /gene="pgaA"
                     /locus_tag="LSX49_001358"
     CDS             complement(51238..53661)
                     /gene="pgaA"
                     /locus_tag="LSX49_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HBL7167789.1"
                     /translation="MYSSSRKRCPKTKWALKILTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALSWFAQKSTLSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALFKLKQLKS
                     GAPDKANLLAEAYIYKLTGRYQDELRAMTESLPENASKQQYPTEYVLALRNNQLAAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSENERYAIADRALAQYAALEILWHDNPDRTAQ
                     YQRIQVDHLGALLTRDRYRDVISHYQRLKKTGQIIPPWALYWVASAYLKDQQPKKAQS
                     IMTELFYNKETIATDLSDEELADLFYSHLESENYPGALTVTKHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEITTRELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLNDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERFFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRHEVSIE
                     GQERIWSSPYLIVDFLPNLYYEQNTEHDTPYYNPIKMFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
BASE COUNT        12954 a        13721 c        14235 g        12969 t
ORIGIN      
        1 ttgttaaaca gtctggagga aataatgaaa gaaaccgata ttgcaggcat tttaacgtcc
       61 actcacacca ttgcgctggt gggggcaagc gacaaacccg atcgtcccag ctatcgcgtg
      121 atgaaatatc tactcgacca ggggtatcac gtcattcctg tttcgccaaa agttgccggc
      181 aaaacactgc tgggccagca ggggtatggc acgctggcag acgttccgga aaaagtcgat
      241 atggtcgatg ttttccgtaa ttcagaagcg gcgtggggcg tggcgcagga agctatcgcc
      301 attggcgcga aaaccctctg gatgcaactg ggggtgatta atgagcaagc ggcagtactg
      361 gcacgggatg ccgggttaaa tgtggtgatg gatcgctgcc cggctattga gatccctcgc
      421 ctgggcctgg caaaataaaa aatacccgga aggcgaaaac cttccgggta tgtttatgag
      481 aattagttac gcagacgcgg cgcctggagt tgtttgcgga tggtctgcgc cagctcatcc
      541 atggatggct gttcaggatg ttcatcctgc aattcgctac ttagctgggc ttcagccagg
      601 taggtatgaa ccggtaggcc gttatcatcc tccatcacca cgtgatacca cggagcggcg
      661 cgaagctcgt cattcaccgc cagctcatca ggcgacggtt cagagagcga gtaaaccggg
      721 tcgatatcca cgaccactcc gagataacct aacagggaat ggcggacctg ctggccgata
      781 ccgaatttgc tggcaatcat agtcacctcc cgggaaatct ttacctttga tataagggta
      841 aaattccaca tttcaagtta catgacgcga caggcaaacc ctttcagata tagcccttcc
      901 gggtaggtag cgatcaccgg atgatcggcg gcctgacgga actgctctat aaattgtaca
      961 tcacgaccgg catcaattgc ggcatccgcg atgattttct gaaataaatc gctggtcatc
     1021 agaccggaac aggagaaagt caggagaaca ccgccttcat tcagcaactg aatcgccagc
     1081 atgttgatgt ctttatagcc acggcacgcg cccatcaact ggcttttatt ctcaacaaac
     1141 ttcggcgggt ccatcacgat aacatcaaat ttttcaccgc gatcgcgata agtacgcagc
     1201 aatttaaaga catcatcacg gacaaactct gccttgctca gatccagttt gttcagctca
     1261 acgttctgcc gtgcaatatc cagcgcttcc tgggaggtat caacgctgac aacctggctg
     1321 caaccgccca tcaatgccga tacggcgaaa ccaccggtat aggagaaaca gttaagtacg
     1381 cgtttatttt cgacgtagcg gcgggtagcc aggcggctgt cacgctggtc caggtagtag
     1441 cccgttttgt gcccgtgctg aatatccacc agcagtttca tgccgtgttc ttcaatcggc
     1501 agcagggcag gcggcaactc gccggtgatg gggccctgag tcagctccat cccttctttt
     1561 ttacgtaccg cgacgtcgct gcgatcgtaa atggcacatt ccgggtacaa cgtttgcagg
     1621 gcgctaatta atgccgcgcg ctgatactct gcgccagcac tcagcaattg cagcaccaga
     1681 aaattaccga aacgatcgat agtaataccc ggcaggccat cagattcacc ggcgattaaa
     1741 cgatagctgt cgaggccatc tttttgcgcc agccagtcac gccatttttg tgcttgctgc
     1801 aaacggcggg taaaaaaagc aatgtcgata gactcagacg ggtcaaacgt ccagacgcgc
     1861 gcccggattt gcgaagctgg cgaataagcg ccgcgtgcta accattttcc ctgatgatca
     1921 acaatatcga tggtttcacc gaggctggct ttaccttcca tgcgggcaac ggccccggaa
     1981 aagacccacg gatggcgacg aagtaatgat ttttcgcgcc ctttggctaa cactaaacgt
     2041 acactcataa tttacttttc tgtcgatgca aagaaatggg cgtcattgtc cggagttttc
     2101 catggatttg caacgcgtcc attaaggata aggagagcag caatgtcgaa agtctgcata
     2161 attgcctggg tttacgggcg agttcagggc gtaggattcc gctacaccac gcagtacgaa
     2221 gcgaaaaaac tgggactaac cgggtacgcc aaaaatcttg acgatggcag cgtggaagtg
     2281 gttgcctgcg gtgaagaagg gcaggtggaa aaattaatgc agtggttaaa aagtggcggc
     2341 ccgcgttctg cgcgtgtgga acgggtgctc agcgagccgc atcatccctc cggggagtta
     2401 acggattttc gtatccgtta aatgcatttt accggtttag gcaggccagc aattttggtg
     2461 gcttgctttg ccggaccttt cgggaacagt cggtacagat agcggctatt gcctttctct
     2521 tcgccaaatt tattcgccat cgcttttacc agcatacgaa tcgccggaga agtattgaat
     2581 tccagataga aatcacgcac aaaacgcacc acttcccagt gttctggcga cagagtaatc
     2641 ccttcgtttt ctgcaatcac caccgccagc ggctcactcc actggctgct ttctttgaga
     2701 tagccttcgg tatccgtttc tatctcttta ccttcgaaga tcagcataat tctttactac
     2761 cttaatcaga ctggcggcag tgtaacaaaa aacaaagccc cgcataaagc gaggctcggt
     2821 aagtaaccct gggcgagatt aatcgcggct ggcgaagccc agaatgctca gcaggctgac
     2881 gaagatgttg tacagcgaaa catacaggct aaccgtggca cgaatatagt tcgtttcacc
     2941 gccatgaatg atgttgctgg tttcaaacaa gatagcgcca gaggagatca gaatgaagac
     3001 cgcgctgatc gccagatgca gagcaggcag ttgcaggaag atattagcaa ccataccaat
     3061 cagcaccacc acaatacccg ccatcagcat accgccgagg aaagacatat ctttgcgggt
     3121 ggtcagcaca tacgcagagc agcagaagaa cactaacgcc gttccgccca gtgccatagc
     3181 gattacgtca cccattccgg cagacagata ggtgttcaga attggtccga ggatataacc
     3241 cagaaaaccg gtaaaggcga atgcggagat aatcccggtc ggcttattcg ccgttttgta
     3301 ggtcaggaac atcaaaccat acatacccac cagcgtcaga atcagacccg gagatggcag
     3361 catcagcacc gtactggcag ttgcggtaat cgccgaaaag gccagcgtca ggctcagcag
     3421 aaaataggta ttacgcagca ccttatgggt gctaagcagc gatgtacggt catgtgaaga
     3481 actaactata cgatccattg agtcactctc tatgacagat gtaattaatt aagcagcata
     3541 atgataatgc gtaagggcac ccagaagttt tacccatctt tacgcatttg atctggaaca
     3601 ggtttaacag cggattatca ggtcattagg cagtgatata acgccctgag aatttcgaca
     3661 ggcaaaagaa aaaggggtta gcatttagct aaccccttat cttatttggc ggaagcgcag
     3721 agattcgaac tctggaaccc tttcgggtcg ccggttttca agaccggtgc cttcaaccgc
     3781 tcggccacac ttccggaatg acgcgcacta taaacatccc gatgcggcgt gtaaacccct
     3841 aatttgtttg tttgcctgaa aaatagccaa aagtgcattg atagcgtgaa acaacagcag
     3901 attgatcatt tcatcaccat gaattccttc tctatttact cgtttagcaa ccggctaaac
     3961 atccccacca cccggcaaaa agaaaaatag gtccattttt atcgctaaaa gataaatcca
     4021 cacagtttgt attgttttgt gcaaaagttt cactacgctt tattaacaat actttctggc
     4081 gacgtgcgcc agtgcagaag gatgagcttt cgttttcagc atctcacgtg aagcgatggt
     4141 ttgccttgct acagggacgt cgcttgccga ccatgtgcgc ccggtgttct gccggtgtcg
     4201 caaggagaag agacgtgcga tatgaataac gaggaaacat tttaccaggc catgcggcgt
     4261 cagggcgtta cccggcgcag ctttctcaaa tattgtagtc tggctgccac gtcgctggga
     4321 ttaggcgcgg gaatggcacc aaagattgcc tgggcgctgg agaataaacc gcgcattccg
     4381 gtggtatgga tccacggcct ggaatgcacc tgctgtaccg aatcttttat ccgctccgct
     4441 cacccactgg cgaaggacgt catcctttcc ctgatttccc tcgattacga cgatactttg
     4501 atggctgccg ccggaaccca ggcggaagaa gtctttgaag acatcatcgc gcaatacaat
     4561 ggcaaatata tcctcgcagt agaaggtaat ccgccgctgg gcgagcaggg gatgttctgt
     4621 atcagcagcg gacgaccgtt tattgagaaa ctcaagcgtg ccgccgctgg agccagtgcg
     4681 attatcgcct ggggaacctg cgcgtcctgg ggctgcgttc aggccgcgcg acctaatccg
     4741 acgcaggcaa cgcctatcga caaagtcatc accgacaaac ccattatcaa agtacctggc
     4801 tgcccgccga tcccggatgt gatgagcgcc atcattactt acatggtgac gtttgatcgt
     4861 ctgccggatg tcgacagaat gggccgtcca ctgatgtttt atggtcagcg tatccacgat
     4921 aaatgctatc gccgcgctca cttcgacgcc ggagagttcg tccagagttg ggatgatgac
     4981 gctgcccgca aaggttactg cctgtacaaa atgggctgca aagggcctac cacctataac
     5041 gcctgttcct ccacacgctg gaacgatggc gtttccttcc cgatccagtc aggtcacggc
     5101 tgcctgggtt gtgcggaaaa tggtttctgg gatcgcggtt cgttctacag ccgcgtggtc
     5161 gatattccac aaatgggtac ccattccacc gccgacaccg tcggtttaac cgcgcttggc
     5221 gtggtggcag cggctgttgg tgtgcacgca gtcgccagcg ccgttgacca gcgcagacgt
     5281 cataaccagc aacctacaga aaccgaacat cagccaggca atgaggataa acaggcatga
     5341 gcactcagta cgaaactcag ggatacacca tcaacaatgc cggacgccgc ctggtggtcg
     5401 acccgattac gcgcattgaa ggccacatgc gctgcgaagt gaatattaac gatcagaatg
     5461 tgatcaccaa tgccgtctcc tgcggcacca tgtttcgcgg gctggagatc attctgcaag
     5521 ggcgtgaccc gcgcgatgcg tgggcgttcg ttgaacgtat ctgcggcgtc tgtactggcg
     5581 tacacgccct ggcttcggtt tacgccatcg aagatgccat cggtattaaa gtgccggaca
     5641 acgccaatat catccgcaac attatgctgg caacgctctg gtgccacgat catctggtgc
     5701 acttctatca gcttgccggg atggattgga tcgatgtgtt agatgcgctg aaagccgacc
     5761 cgcggaaaac ctccgaactg gcgcaaagcc tctcctcatg gccgaaatca tcccctggct
     5821 atttcttcga cgtacaaaac cgcctgaaga aattcgttga aggcggccag ttggggatct
     5881 tccgcaatgg ctactggggg cacccgcagt acaaactgcc gccagaagcc aacctgatgg
     5941 gctttgccca ctatctcgaa gctctcgatt tccagcgtga aattgtcaaa atccacgcgg
     6001 tctttggcgg taaaaacccg catccaaact ggattgtcgg tgggatgcct tgcgccatta
     6061 acattgacga aagcggcgcg gtcggggcag tcaatatgga acgcctgaac ctggtgcagt
     6121 tgattatcac ccgcacggcg gatttcatta acaacgtgat gatccccgac gccttagcca
     6181 tcggtcagtt caacaaaccg tggagcgaaa tcggcacggg gctttctgat aaatgcgtcc
     6241 tcagttacgg cgcgttccct gatatcgcca acgactttgg cgagaaaagt ctgctgatgc
     6301 ctggcggcgc ggtgattaac ggcgacttca acaatgtact gccagtggat ttagttgatc
     6361 cgcagcaggt gcaggagttt gttgaccatg cctggtatcg ttatcccaac gatcaggttg
     6421 ggcgtcatcc gttcgatggc attaccgacc cgtggtacaa ccccggcgat gtcaaaggca
     6481 gcgataccaa cattcagcag ctgaatgaac aggaacgcta ctcgtggatc aaagcgccac
     6541 gctggcgcgg taacgcgatg gaagtggggc cgctggcacg cacgttaatc gcttatcaca
     6601 aaggcgatgc tgcgaccgtt gagtcggtcg atcgtatgat gtcggcgttg aaactgccgc
     6661 tttccggcat ccagtcaacg ttgggccgca ttttgtgtcg cgcgcacgaa gcgcagtggg
     6721 ccgcaggtaa gttgcagtat ttcttcgata aactgatgac caacctgaaa aacggcaatc
     6781 ttgccaccgc ttccacggaa aaatgggaac cagcaacctg gccgacagag tgccgtggtg
     6841 tcggttttac cgaagcgccg cgcggggcgt taggccactg ggctgccatt cgcgatggca
     6901 agattgatct ctatcagtgc gtggtgccga ccacctggaa cgccagcccg cgcgatccca
     6961 aagggcagat tggcgcttat gaagcggcgc tgatgaacac caaaatggcg atccccgagc
     7021 aaccgctgga gatcctgcgt actctgcaca gctttgaccc gtgcctcgcc tgttcaacac
     7081 acgtgctggg cgacgacggt agcgagctta tctccgtgca ggtgcgttaa cagcgaagga
     7141 gaatcatcat gcaacagaaa agcgacaacg ttgtcagtca ctatgtcttt gaagcacccg
     7201 tgcggatatg gcactggctg acagtgttat gcatggcggt gttgatggtc accggttact
     7261 ttatcggcaa gccgctacct tccgtcagcg gcgaggcgac atatctgttc tatatgggct
     7321 acatcaggtt aattcacttc agcgccggga tgatttttac cgtggttttg ctgatgcgga
     7381 tctactgggc ttttgttggc aatcgttact cccgcgagct gtttatcgtg ccggtatggc
     7441 gtaaaagctg gtggcagggc gtgtggtatg aaatccgctg gtatctgttt ctggcaaaac
     7501 gtccgagtgc cgatataggc cataacccca tcgcccaggc ggcgatgttc ggctatttcc
     7561 tgatgtcagt ttttatgatc atcaccggct ttgcgctgta cagcgaacac agccagtacg
     7621 ctatttttgc gccgttccgt tatgtggtgg aatttttcta ctggacgggc ggcaactcaa
     7681 tggacattca cagctggcat cggctgggga tgtggctgat tggcgcattt gtgatcggcc
     7741 atgtctacat ggcgctgcgt gaagacatca tgtccgacga cacggtgatc tccactatgg
     7801 tcaacggcta ccgtagccac aaatttggca aaataagtaa caaggagcgt tcatgagcga
     7861 gcaacgcgtg gtggtaatgg ggctgggcaa cctgctgtgg gccgatgaag gcttcggcgt
     7921 gcgggtggcg gaacggctgt atgcccatta ccactggccc gaggatgtgg agattgtcga
     7981 tggcggcacc caaggactga acttgctggg gtatgtcgaa agcgccagtc atctgttgat
     8041 tctcgatgcc attgattacg ggctggaacc cggaacgcta cgaacgtatg ccggagaacg
     8101 cattccggct tatctcagcg cgaagaaaat gagcctgcac cagaacagtt tctccgaagt
     8161 gctggcgctg gcagatatcc gcggacatct gccagcacat attgccctcg tcggtctgca
     8221 acccgcaatg ctcgacgact acggcggcag cctgagcgaa ctggcgcggg agcaactgcc
     8281 cgccgcggaa caggcggcgc tggcgcagct ggctgcgtgg ggaattgtgc cgcaaccggc
     8341 taatgaatcg cgctgtctca attatgactg tctgtcgatg gaaaattacg aaggcattcg
     8401 tttgcgccag taccggatga cactggagga gcagggatga gcaacgacac gccatttgat
     8461 gcgttgtggc aacgaatgct ggcgcgcggc tggacgccga tcagtgaatc ccgtcttgac
     8521 gactggctta cgcaagcgcc agacggcgtg gtgttattaa gcagcgatcc gaaacgcacg
     8581 ccagaggtca gcgataatcc ggtaatgatt ggcgaattat tgcgcgagtt tcccgattat
     8641 acatggcagg tagcgattgc tgaccttgag cagagcgaag ccatcggcga tcgctttggc
     8701 gtctttcgct ttcccgccac attagtattt acctgcggaa actatcgcgg cgtgctgaat
     8761 ggtattcacc cgtgggcgga actgataaac ctgatgcgcg gacttgtcga accgcagcag
     8821 gagcgtgcct catgagcgaa acttttttcc atctgctggg gccaggaacg caactgaacg
     8881 atgacagttt cagcatgaat ccactgccga tcacctgtca ggtgaatgat gaaccgagta
     8941 tggcggccct ggagcaatgt gctcacagcc cgcaggtgat tgcgctgtta aacgagttac
     9001 aacatcaact aagcgaacgc cagccgccgt tgggcgaggt actggcagtc gatctgttaa
     9061 atctcaacgc cgacgatcgt cactttatca atacgcttct cggggaaggg gaagtgtcag
     9121 tgcgcattca gcaggctgat ggtagtgaaa gtgaaattca ggaggcgatc ttctgcggat
     9181 tatggcgggt acgcagacgt cacggcgaac agttgctgga agacaaactg gaggctggct
     9241 gcgcaccgct ggcgttgtgg caggcggcaa cgcaaaacgt cttgccgaca gattcgctgt
     9301 taccgccgcc cattgatggc ctgatgaatg gcctaccgtt ggcccatgaa ttactggcac
     9361 atgtacgtaa ccccgacgca cagccgcaca gcattaatct gacgcaatta cccatcagcg
     9421 aagctgaccg gctttttctc tcacgtctct gtgggccggg aaatattcag attcgtacca
     9481 ttggctatgg cgagagctat atcaacgcca cggggttacg ccatgtctgg catttacgct
     9541 gtacggacac cttaaaaggc ccgttactgg aaagttatga aatctgccca ataccggaag
     9601 tggtgctggc agcgccagaa gatttggtcg actctgcgca gcggcttagc gaggtatgcc
     9661 agtggctggc ggaaggtgca ccgacgtaaa aagacggtaa gtatcgcttt caggcttatg
     9721 aatatcgcaa tcggcgaata cctctggtcg tagagtttca ggataaagag ggagatctac
     9781 cattaacggg ttatttttct ctcttcgcct acaggagtgc gcatgtggga tgtcattgat
     9841 ttatcgcgct ggcagtttgc tctgaccgcg ctgtatcact ttttatttgt accccttacc
     9901 ctggggctga tttttttgct ggctatcatg gaaaccattt acgtggtcac cggcaaaaca
     9961 atctaccgcg atatgacgcg cttctggggt aagctcttcg gtatcaactt tgctcttggc
    10021 gtggctaccg gcctgacgat ggagtttcag tttggtacta actggtcatt ctattccaac
    10081 tatgtgggcg atatttttgg cgcaccactg gcgatggaag cattaatggc cttcttcctc
    10141 gaatccacct ttgtcgggct gttcttcttc ggctggcaac ggctgaataa ataccagcac
    10201 ctgctggtga cgtggctggt ggcgttcggt tcaaatctct ctgcgttgtg gatattgaat
    10261 gccaacggtt ggatgcaata cccgactggt gcgcattttg atatcgacac cctgcgtatg
    10321 gagatgacca gtttcagcga gctggtcttt aacccggtca gccaggtgaa atttgtgcac
    10381 accgtaatgg cgggatacgt gaccggggct atgtttatta tggcgatcag cgcctggtat
    10441 ttactgcgcg gacgggagcg cgatgtcgca ttacgctcgt ttgccatcgg ttccgtcttc
    10501 ggtactctgg cgattatcgg tacgctgcaa ctcggagaca gttctgcgta tgaagtcgcg
    10561 caagtacaac cggtaaaact ggcggcgatg gaaggggagt ggcaaacaga acctgcacct
    10621 gcaccgttcc atgtggttgc ctggccggaa caggatcaag agcgtaacgc ctttgccatc
    10681 aaaattcccg cgctgctagg gatcctcgcc actcactcat tagataaacc cgtgccgggt
    10741 ctgaagaatt tgatggctga aacctaccct cgcttgcaac gtggacgtat ggcctggctg
    10801 ttaatgcagg aaatatcgca aggcaatcgt gagccgcatg tgttgcaggc attccgggag
    10861 ctggaaggcg acctgggtta cggcatgttg ctctcccgct atgcgccgga tatgaatcat
    10921 gtcacagccg cacagtacca ggcggcgatg cgtggcgcga tacctcaggt tgcgccggta
    10981 ttctggagtt tccgcatcat ggtgggctgt ggttccctgc tgctactggt gatgctgatt
    11041 gcgcttgtcc agacgctgcg tggcaaaatc gaccagcatc gctgggtgct gaaaatggcg
    11101 ctctggagtt tgccgctgcc gtggattgcg attgaagccg gatggtttat gaccgagttt
    11161 ggtcgtcagc cgtgggcgat acaggacatc ttaccgacat actccgcgca ctccgcctta
    11221 accacaggac aactggcttt ctcactgatc atgatcgtag ggctttacac cctgttctta
    11281 atcgccgaag tctacctgat gcagaaatat gcccgtctgg ggccgagcgc gatgcagagt
    11341 gaacaaccga cgcagcaaca ggggtaaagg agaaaatcat gtttgattat gaaacattgc
    11401 gtttcatctg gtggctgctg attggcgtga tcctggtggt ctttatgatc tccgacggat
    11461 ttgacatggg gatcggctgt ctgctgccgc tggtggcgcg taatgatgat gaacgtcgga
    11521 tagtgataaa cagcgttggc gcgcactggg aaggcaatca ggtctggttg atcctcgcag
    11581 gtggggcatt atttgccgcc tggcccagag tgtatgcagc ggcgttttcc ggcttttatg
    11641 tggcgatgat tctggtgctg tgctcgctgt tcttccgccc gctggccttt gattatcgcg
    11701 gaaaaatcgc cgatgcacgc tggcgtaaaa tgtgggatgc cggactggtc atcggcagtc
    11761 tggtgccgcc ggtagtcttc ggtattgcat tcggcaactt gctgctcggc gtgccgtttg
    11821 ctttcacacc gcaattacgc gtggaatatc tcggcagctt ctggcaactg ctgacgccat
    11881 tccctttatt gtgtggattg ctcagtcttg ggatggtgat tttgcaaggt ggcgtctggt
    11941 tacaactgaa aactgttggt gtgattcatc tgcgttcaca gctggcgacc aaacgcgccg
    12001 cactactggt gatgctgtgc tttttgctgg cgggttactg gctgtgggtt ggtattgatg
    12061 gctttgtgct gctcgcccag gatgctaacg gtccttccaa tccattaatg aaactggtgg
    12121 cagtgctacc tggtgcctgg atgaataatt tcgtcgaatc gcccgttttg tggatcttcc
    12181 cgctgctggg gttcttctgc ccattgctga cggtgatggc gatttatcgt ggtcgcccgg
    12241 gttggggatt tttgatggcg tcattgatgc aatttggcgt gattttcacg gcaggcatca
    12301 cgctgttccc ctttgtcatg ccgtcaagcg tgagtccgat ctccagcctg acgttgtggg
    12361 acagcacttc cagtcagctg acgctgagca ttatgttggt aatcgtgctg atatttttgc
    12421 ccattgtgtt gctctacact ctctggagct actacaaaat gtgggggcgc atgacgacag
    12481 aaactctccg ccgtaacgaa aacgagctgt actaaggagc aggaacaatg tggtatttac
    12541 tttggttcgt cggcattttg ttgatgtgtt cgctctccac ccttgtgttg gtatggctgg
    12601 acccgcgtct gaaaagttaa cgaaggtaag cctgatgagg cgcattagcg tcgcatcagg
    12661 caatcaataa tgtcggatat gaaaagcgga aacatatcga tgaaagcgat cttgatccca
    12721 ttcttatctc ttctgattcc gttaacaccg aaatctgcat tcgctcagag tgagccggag
    12781 ctgaagctgg aaagtgtggt gattgtcagt cgtcacggtg tgcgtgcacc aaccaaggcc
    12841 acgcaactga tgcaggatgt cacccctgac gcatggccaa cctggccggt aaaactgggt
    12901 tggctgacac cgcgcggtgg tgagctaatc gcttatctcg gacattacca acgccagcgt
    12961 ctggtggccg acggattgct ggcaaaagag ggctgcccgc agccaggtca ggtcgcgatt
    13021 attgctgatg tcgacgaacg tacccgtaaa acaggcgaag ccttcgccgc cgggctggca
    13081 cctgactgtg caataaccgt acatacccag gcagatacgt ccagtcccga tccgttattt
    13141 aatcctctaa aaactggcgt ttgccaactg gataacgcga acgtgactga cgcgatcctc
    13201 agtagggcag gagggtcaat tgctgacttt accgggcatc ggcaaacggc gtttcgcgaa
    13261 ctggaacggg tgcttaattt cccgcaatca aacttgtgcc ttaaccgtga gaaacaggac
    13321 gaaagctgtt cattaacgca ggcattacca tcggaactca aggtgagcgc cgacaatgtc
    13381 tcattaaccg gtgcggtaag cctcgcatca atgctgacgg agatatttct cctgcaacaa
    13441 gcacagggaa tgccggagcc ggggtgggga aggatcaccg attcacacca gtggaacacc
    13501 ttgctaagtc tacataacgc gcagttttat ttgctgcaac gcacaccaga ggttgcccgc
    13561 agtcgcgcca ccccgttatt ggatttgatc atgacagcgt tggcgcccca tccaccgcaa
    13621 aaacaggtgt atggtgtgac attacccact tcagtgctgt ttatcgccgg acacgatact
    13681 aatctggcaa atctcggcgg cgcactggag ctcaactgga cgcttccagg tcagccggat
    13741 aacacgccgc cagggggtga actggtgttt gaacgctggc gtcggctcag cgataacagc
    13801 cagtggattc aggtttcgct ggtcttccag actttacagc agatgcgtga taaaacgccg
    13861 ctgtcattaa atacgccgcc cggagaggtg aaactgaccc tggcaggatg tgaagagcga
    13921 aatgcgcagg gcatgtgttc gttggccggt tttacgcaaa tcgtgaatga agtacgcata
    13981 ccagcgtgcg ctctccatca agacaaataa acatttgccg ctgttggtcc acgcaggcca
    14041 tttacgcggc aaaattccac gcgtaatcct ggtataagca cttctgcgtc gcggggagtg
    14101 aatgcggaaa tatggacctg gacttcttta cgaccgtcgg aggggataat gaatcctttg
    14161 ccgcttttgc gatcaaaggt tttgacaatt cctgtcattt tacgggacaa acaaattcct
    14221 tactgaaaat actgcgctgc actatacggg gttaataaaa taaagccagc gatatttaag
    14281 accgccggac ggctaaaata aaatttgctt aatctcaatt atcatgcgtt aatagctgcg
    14341 tcggtttgaa agacagacag catacaaagt agtttactaa agcagttctc attatcaggc
    14401 attatcccct tcttttgagt ctctctcctg aacactaagt agtttctgta ttaaagccct
    14461 gtttgccgaa aggcccaaaa tgaaggaagt aaaatatgtc taataaaatg actggtttag
    14521 taaaatggtt taacgcagat aaaggttttg gctttatcac tcctgatgat ggcagcaaag
    14581 acgttttcgt ccatttcact gccatccaga gcaatgaatt ccgcacgctg aacgaaaatc
    14641 agaaagttga attttctatt gagcaggggc aacgtggtcc cgcggcagcg aacgttgtta
    14701 cgctctaagg ttgccgttat tactcaacat ctccatttcc gctgtccatg ttgccatggt
    14761 tcacagtacc gcacatcggc attcgatgtg acggagcgaa accctttggg tgcaaagtgc
    14821 attttttgta aatcgacgat gatcaccttt gataacgttg cgctgcaaat acgcactgac
    14881 catgcgccgc tggatttcac aaaataatat caggctccct cgtggagcct tttttatatc
    14941 tgccttattt ttcttcaacg ctgtatgtat agtaagcgat aacctgttga ttattgaatc
    15001 tttcggggag atggcttata acatttctta cctgaccagg gtaccgggaa ccaacacctt
    15061 actggcgtgt tgctgtcttt taagaccaga agaggttaac agtgaatatt gaagagttaa
    15121 aaaaacaagc cgaaacggaa atcgccgact ttatcgcgca aaaaatcgcc gagctgaaca
    15181 agaatacagg gaaagaagtc tctgaaattc gcttcaccgc acgagaaaaa atgaccgggc
    15241 ttgaaagtta tgatgtcaaa atcaaaataa tgtgattttg tgaacatcac cccgtgcgag
    15301 gtgatgttcc gcttgttgct aatttagtga ccaatcattg gcgattgcgg aattaagcgt
    15361 tggtacaatt cctccggcac cgggctttgc catactcccg catacattgc gtaaccaatc
    15421 gccgcaaaca taatccccat aaccagtagc gtcattaacc agccagacaa cgcaaaggct
    15481 tttttatttg ccgcaggttt ttgcagtgaa aaggccaatg ttgaggctac cggacatgac
    15541 tctacgcaag tcatacagcc ggtacattcc actgttcgta cctgaattaa tttatcgacc
    15601 gggatccgtg atgggcaact ttttgcgcat ttgccacaat cgatacaact ttcggcattg
    15661 cgacgaatct taaacggcga taatagcgaa accacgccca tcagcgcgcc atatgggcaa
    15721 agataacgac accaggcatg gcgaataaac aggctggcaa tcagcaaaac gatcatgctg
    15781 attaatgtcg cggtccccat atgacgaaag aaatcgagca ttttaacgtc catcaccacg
    15841 ctgtagggcg acaacataaa atagtgaatc gcctgagcgg gcatcaataa cgcgatatag
    15901 agaaaaaaac tcaacagcaa atacttcacg ccgcgcagag gaatatccag ccagcgggga
    15961 aggacaaatt gccgaccaaa cagtttgtta ccgagatcgc cgattaattc cgaaagcgta
    16021 ccaaccgggc ataaccatga acaaaaggcc tttttgagta atagactgat gacgataaaa
    16081 gcgaccaata acagcatcgc ggcggcgtgg acggacggta actgacctgt tgcaaggcta
    16141 tatttcagat tcatcagacc ggcaatcggt agccagcctt cgataccacc cggtctggtg
    16201 acaaatgtcg tactacctgc cgtttcgtaa tagcgcaccc aataccagaa cgtgatggca
    16261 atataaatat taattgccaa cagtaataat tgcgtcgctt tacgccaggt cgtggcattg
    16321 cgccagtcat tccacggtaa tttgccgccc gtcgtgcctg gccgccgttg ccagcgggtt
    16381 ctttttttct ctgccatgat tttgccagtc cgttaagttg cataccaaat gccactattc
    16441 tagttgttct taactggctg atattgattc aaatcgcgtt caggtctttc ttattaacca
    16501 tgcttccaga gcggcaacac tgcgtgtaat ttcttcgtgt ggaagggggg cagataatgg
    16561 ctgctgctcc agttgtgcgc attgctggct ggcgctacgc attcccagac tcgagcaact
    16621 gctttttagc tgatgtgcgg cacgctttat tttctcgtta tcctgactgg cgcgggcaat
    16681 gtcgatttca tcgagaagcg gcagggcatg ttgtttaaat aatatcagcc attcgtggat
    16741 cttctccgcc cccattaaat gagcatcttc attgagttgc gatacatcca gtggttgatc
    16801 gttattgact tgcagttgga gatagtgcgc cagtaattga ccgagcactt cacgcggcac
    16861 cggtttaggg ataatcccgc gaaatagcga actggtacgc tgtcgcagtg tttcgtcaat
    16921 gacatgggcg ctaaagccaa tcaaaaccag cgacggatat tgctgtgcca gttgtcgggc
    16981 aagcgtaatg ccgtcgatat ccggtagatc aaaatccacc agtgcggcag caaacggttc
    17041 actattttgc agtgtctcta aagcctgcgc ggcatttcct acggcaacga cctgcgcccc
    17101 actgctgttc aacatctcaa cggtaatccg ctgggttagc gggttatctt caattaacag
    17161 caaacgtaaa ccgtccagac gcaccgcctg attgactgtt tttggcacgg gtgcagtggc
    17221 aacacgtaac ggcacgcgta aacaaaaaca gcttccaacc tccggcgtgc tggtggcgct
    17281 caattcgccg cccatcgcct gggccagacg gctactgata gtcagcccca gcccggtgcc
    17341 gccgcgtttg ccgctaacct gaacaaatgg ctggaagatt tcagccagtt tcgcgggatc
    17401 aataccgcag ccgctgtctt ccacttcgac cagccattgt tcgccatcaa tgcgactacg
    17461 cagaataatg tgcccttcgt cggtgaaacg cagggcgttg ctcaacaggt tggtaatgac
    17521 ctgacgaata cgccgcggat cgcccattaa cgcagtcggt acatcgtcgg caatttctgt
    17581 tgccaggcga atcgggcgac ctttcaccct tccgctcatt aattgcaggg tactttccag
    17641 cagcgggcgc ggttcaaagg gttcatcgct gaccgaaaca ttcttgccgc ctgcttcgat
    17701 agccgaataa tcgagaatat cgttgaggat ggtcagcaac gattcaccag agtcggtaat
    17761 cgcccgcaaa tcatcgcgct gggcgttaag tgcggggtta tctgccagca gctgtgcggt
    17821 gccgagaata ccgtacagcg gtgtgcggat ctcatggctc atcgccgcca gaaacgccga
    17881 ttttgcctgg ctggcttttt ctgcttccgc ccgtgcctgt cggtgttcta tcaccagttc
    17941 ctgcaattca gctgtacgcg ctttgacctg cgccgccagc tgttcgcggt ggcgattcag
    18001 tgcatgaaca ctgctgcgaa acgcatccat cagccgcccg atggtatcca gttcccgtac
    18061 gccagcggtt tccgggaaag gggagtcgat atcaccatcc agcaagcgtt gcagcgcctg
    18121 cgtttgttct gcaagagggc gcgtgactga gcgataaacc acgcgccaga ggatcagaat
    18181 cagtgcgcaa agagaaacta atcccagcaa taacaggctg tattgcccgc gtgcactggc
    18241 tttttccaga tgagccagcc cgtgctgatt acgcagctca atggtgtcga ccagctgact
    18301 gacttcgcta ctaaactgcg cgaattgggc gatgttattt tgggcgagag tttgcaggtg
    18361 attgctgatt tcactgtcct gctgatacag cgccagcaaa tcgctatatt ggctaacggt
    18421 agttaacgtt gttgctacct gagtacgaac acccggatct tcaatgcgta tttgccgacg
    18481 ttgcagaatt ttcaccgcat tattgagctg cttttccagc gttggcgcat ttttctggat
    18541 ctgttccagc cccagattca tcaccatttg ctgcacccgc agggcgctaa ggcgcagttc
    18601 attcatctgg ttaacatact caagatcgat atcaatcagc cgatcgagtg cactttctgc
    18661 ggcttgacgc tgatgttgtt cgatcaaatc gtaaatcccg gcctgggtcg ctccggcgga
    18721 ggttgccgca ttattcgcct gaccttgcgc caggcgtgcg atttcatcgg cggcggcgac
    18781 tatctgctga ctgagttgct gttgttgctg gcgaagttgc aaacgctgcc ccaccagttc
    18841 cccttgctga cgtaacgaac gggagatctc ctgctcctgt tgttcaatag cggtggtgtc
    18901 aaaaccttgt tcccgtaacg cttgcagcaa cgcattaatc ttcagacttt gtgcggtgag
    18961 cattcgcccc tgcgcctgcc acatcttttc gttatcggca ctggtcaggt tctgcgcggc
    19021 gaaaagttcc caggcgctgg cttcgctcaa ctggcgcgcc atattcatgg taggaatcaa
    19081 tgcctgagtg ttgtcttttt ccacctggct gataaagcgc aggttgtacc atcccaccag
    19141 ggtactggtc agggttaaca gcgccatcag ggcaaagccc atccagagtc ttcgggtcag
    19201 ggttaaattc acggtcggtg cacttaaggt gaaaaaggtt gagtcgcaaa gcggaatgca
    19261 tctagcataa agccttatta ttgatgaggc tatcatgcgc gtactgctat ttttacttct
    19321 ttcccttttc atgttatcgg cattttcggc tgataacctg ttgcgctggc atgatgcgca
    19381 gcatttcacg gtgcaagcct ctacgccgct taaagccaaa cgcgcatgga aactgtgcgc
    19441 gctttatccc agcctgaaag attcatactg gttatcgttg aactatggta tgcaggaggc
    19501 tgctcgccgc tacggtgtgg atttaaaagt gctggaggca ggcggctaca gccagttggc
    19561 tacccagcaa gcacaaatcg accagtgtaa acagtggggc gcagaggcca ttttgctcgg
    19621 tagtagcacg acgtcatttc ccgatctgca aaagcaggta gcaaatctgc cggtgatcga
    19681 actggtaaat gctattgatg ctccccacgt gaaaagccgc gttggtgtgc cctggtttca
    19741 gatgggctat caaccagggc gatatctggt gcaatgggcg cacggtaaac cactgaacgt
    19801 gctgttgatg cccggccccg ataacgccgg gggcagtaag gagatggtag agggttttcg
    19861 cgcagccatt gccggaagcc cggtgcgtat tgttgatatt gcgctcggtg ataacgatat
    19921 tgaaatccag cgtaacctgt tgcaggagat gctggaacgc catccagaaa tcgacgtcgt
    19981 tgccggaacg gccattgcgg cagaggcggc aatgggggaa gggcgtaacc tgaaaacgcc
    20041 gcttaccgtg gtgtcgtttt atctttcaca tcaggtgtat cgcgggttga agcggggaag
    20101 agtgattatg gctgccagcg atcaaatggt ctggcaaggg gaactggcgg ttgagcaggc
    20161 catcaggcaa ttacaggggc aatcggtgtc tgataatgtc agcccaccga ttttagtcat
    20221 gacgccgaaa aatgccgacc gcgaacatat ccgccgctcg ctgtcaccag ggggatttcg
    20281 tccggtttat ttttatcagc acacatcagc ggctaagaaa taaccttcgc catgttgtgt
    20341 caccagtaaa tccgcactga gtttatggcg taaacgacga attaacacat cgacggtgcg
    20401 caggtcaggg ttttccaccc gacgcgcaga gagcatacgc agcagacgtt cacggctgag
    20461 aatttcgccc ggattagtca caaatgccac cagcatttca tactctgcgc gggtcagttt
    20521 aatcggctcg ccatcccgct ccagcgtatg gcgcgacaca ttcaggcaat aaccggcaaa
    20581 gcgatagcag ttgtcctgag tgtgcggttg cgcctgtcgc gcgaggtcga ttcgccagag
    20641 caaatttttc actcgtacca ccagttcgcg cagctccagc ggtttggtga cgtaatcgtc
    20701 tgcgcccatt tccagcccaa caatacggtc aatccgatcg ctgcgtccgg taaccagaat
    20761 aatccctacc gttgagcgtt ctcgcagggc gcgggttaac atcaggccat tttcatcggg
    20821 caaattgata tccagcagaa tcaaatccac cggctgattc tgcataattt cccgcagccc
    20881 ggcaccgctc gccgtaacgg aaacggtata cccctcctga gtgaagtaag attgtaatcg
    20941 cgcctgggta accggctcat cttcaacaat aacaatgtga tgtggcatca gagggtttta
    21001 ctcattctgt tcatatctgt tcatattctg ccgtaagccg ttcatcctga ccagtgccgc
    21061 tgttcatatt tgctcattaa gatcgcttca ctaaaccata attttacagg ggctattatg
    21121 cggaaactct ggaacgcgct acgccgaccc agtgctcgtt ggtcggtact ggcgctggtc
    21181 gctactggga ttgtgattgg cattgcgctg attgtattgc cacacgttgg gatcaaagtc
    21241 accagcacaa ccgaattttg tgtcagttgc cacagtatgc aaccggtgta tgaagaatat
    21301 aaacagtcgg tgcatttcca gaacgcctcc ggcgtgcgag ctgaatgcca tgactgtcat
    21361 atcccgccgg atattccagg catggtgaag cgcaaactgg aagcgagcaa cgacatttac
    21421 cagaccttta ttgcccactc cattgataca cctgagaaat ttgaagccaa acgcgcggaa
    21481 cttgccgagc gtgaatgggc gcgaatgaaa gaaaacaact cggcaacctg ccgctcctgc
    21541 cataactacg atgcgatgga tcatgcgaag cagcatcctg aagcggcgcg tcagatgaag
    21601 gtggcagcga aagataatca atcctgcatc gactgtcata aaggtattgc ccaccagtta
    21661 ccggatatga gtagtggctt ccgtaagcag ttcgatgagc tgcgcgccag tgctaatgat
    21721 agtggtgaca cgctgtactc cattgatatt aagccgattt atgcggcgaa aggcgataaa
    21781 gaagcgtctg gttctctgct gcctgcttcg gaagtgaaag tccttaaacg tgacggcgac
    21841 tggctgcaaa ttgaaatcac tggctggacg gaaagtgcag gacgtcagcg tgtactcacc
    21901 caattcccag gtaaacgcat ctttgttgcc tcgattcgtg gtgatgtgca gcagcaggtg
    21961 aaaacactgg agaaaaccac cgttgccgac accaataccg agtggagcaa gttgcaggcc
    22021 actgcgtgga tgaagaaagg cgacatggtg aacgatatca aaccgatctg ggcttatgcg
    22081 gattcgctgt acaacggcac ctgtaaccag tgccacggcg caccggaaat atcccacttt
    22141 gacgctaacg gttggatcgg cacgctcaac ggcatgattg gctttaccag cctcgataaa
    22201 cgtgaagaac gcactttgtt gaaatatctg caaatgaatg cgtctgacac cgcaggtaaa
    22261 gctcacggcg ataagaagga agaaaaataa tgaacaataa cgatctcttt caggcatcac
    22321 gtcggcgttt tctggcacaa ctcggcggct taaccgtcgc cgggatgcta gggccgtcat
    22381 tgttaacgcc gcgccgtgcg actgcggcgc aagcggcgac tgaggctgtc atctcgaaag
    22441 agggcattct taccgggtcg cactgggggg ctatccgcgc gacggtgaag gatggtcgct
    22501 ttgtggcagc aaaaccgttc gaactggata aatatccgtc gaaaatgatc gccggattgc
    22561 cggatcatgt acacaacgcg gcgcgtattc gttacccgat ggtacgcgtg gactggctgc
    22621 gtaagcgcca tctgagcgac acctcccagc gcggtgataa ccgttttgtg cgcgtgagct
    22681 gggatgaagc cctcgacatg ttctatgaag aactggaacg cgtacagaaa actcacgggc
    22741 cgagtgcctt gctgaccgcc agtggttggc aatcgacggg gatgttccat aacgcttcgg
    22801 ggatgctggc gaaagctatt gccttgcatg gtaatagcgt tagtacgggc ggagattact
    22861 ctaccggtgc tgcgcaggtg atcctgccgc gcgtggttgg ctcaatggaa gtgtatgaac
    22921 agcaaacctc ctggccgctg gtattgcaga acagcaaaac cattgtgctg tggggctccg
    22981 atttgctgaa aaaccagcaa gcgaactggt ggtgcccgga tcacgatgtt tatgaatatt
    23041 acgagcagct aaaagcgaaa gtcgccgccg gtgaaattga ggtcatcagc atcgatccgg
    23101 ttgtcacatc cacccatgag tatctggggc gcgagcatgt gaagcacatt gcggttaacc
    23161 cgcaaactga cgtgccgctg caactggcgc tggcgcatac gctgtacagt gaaaacctgt
    23221 acgacaaaaa cttcctcgct aactactgtg taggttttga gcagttcctg ccgtatctgc
    23281 tgggtgagaa agacggtcag ccgaaagatg ccgcatgggc tgaaaaactg accggcattg
    23341 atgccgaaac cattcgtggg ctggcacggc agatggcggc gaacagaacg cagattattg
    23401 ctggctggtg cgtacagcgt atgcagcacg gtgaacagtg ggcgtggatg attgtcgttc
    23461 tggcggcgat gctggggcaa attggcctgc caggtggtgg ttttggtttt ggctggcact
    23521 ataacggcgc aggcacgccg gggcgtaaag gcgttatttt gagtggtttc tccggctcta
    23581 cgtcgattcc gcctgttcac gacaacagtg actacaaagg ctacagcagc accattccga
    23641 ttgcccgttt tatcgatgcg atcctcgaac cggggaaagt gatcaactgg aacggtaaat
    23701 cggtaaaact gccgccgctg aaaatgtgta tttttgccgg aactaacccg ttccatcgcc
    23761 atcagcagat caaccgcatt attgaaggct ggcgcaagct ggaaacggtt atcgccatag
    23821 ataaccagtg gacctcaacc tgccgctttg ccgatatcgt gctgcctgcg accacgcagt
    23881 ttgagcgtaa cgatctcgac cagtacggca accactccaa tcgtggcatc atcgccatga
    23941 aacaggtcgt gccgccgcag ttcgaggcgc gcaacgactt cgatattttc cgcgagctgt
    24001 gccgtcgctt taatcgcgaa gaagccttta ccgaagggct ggacgaaatg ggctggctga
    24061 aacgcatctg gcaggaaggt gtacaacagg gcaaaggacg cggcgttcat ctgccagcgt
    24121 ttgatgactt ctggaataac aaagagtatg tcgagtttga ccatccgcag atgtttgttc
    24181 gccaccaggc attccgcgaa gatccggatc tcgaaccgct gggcacgccg agtggcctga
    24241 ttgagatcta ctcgaaaacc atcgctgata tgaactacga cgattgtcag gggcatccga
    24301 tgtggtttga gaaaatcgaa cgctcccacg gtgggcctgg ctcgcagaag tatccgttgc
    24361 atctgcaatc tgtgcatccg gatttccgac ttcactcgca gttatgtgag tcggaaactc
    24421 tgcgtcagca atataccgta gcgggtaaag agccagtatt tattagcccg caggatgcca
    24481 gcgcgcgcgg tattcgtcac ggtgatgtgg tacgcgtctt taacgttcgt ggtcaggtgt
    24541 tggctggagc agtggtttct gaccgttatg cacccggcgt ggcgcgaatt cacgaagggg
    24601 catggtacga tccggacaaa ggcggcgagc caggggcgct gtgcaaatac ggtaacccca
    24661 acgtcttgac catcgacatc ggtacttcgc agctggcgca ggcgaccagt gcgcacacta
    24721 cgctggtgga aattgagaag tacaacggaa cagtggagca ggtgacggcg tttaacggcc
    24781 ccgtggagat ggtggcgcag tgcgagtatg ttcccgcgtc gcaggtgaaa tcatgaccac
    24841 gctgacagca caacagattg cctgtgttta cgcctggctg gcgcagttgt tctcccgtga
    24901 actggacgat gaacaactga cgcaaatcgc cagtgcgcag atggctgaat ggttttcgtt
    24961 gctgaaaagc gaaccgccgc tcactgcggc ggtgaatggg ctggaaaaca gtattgccac
    25021 tctgacagta cgtgacgatg cccgtctgga actggccgct gacttttgcg gcctgtttct
    25081 gatgaccgac aaacaagcgg cgctgccgta tgcatcggcc tacaaacagg acgagcaaga
    25141 gattaaacgc ttgttagttg aggcggggat ggaaaccagc ggcaatttca acgaaccggc
    25201 agatcatctg gcgatctatc tcgatttgtt gagtcatctg catttttcgc tgggagaggg
    25261 gaccgttcct gcgcgaagaa tcgacggttt gcggcaaaaa acactgacgg ctctgcggga
    25321 atggttacca gagtttgctg cgcgttgtcg acagtatgac agctttggtt tttacgcggc
    25381 actaagccag ttattgctgg tgttagtgga gtgtgactac caaaaaagat aatgccgttt
    25441 gtaggcctga taagacgcgg caggcgtcgc atcaggcatt agtgcgcagt tgccggatgc
    25501 ggcgagaacg ccttatccgg cctacgggaa cagtgctttt tgtgggcctg ataagatgcg
    25561 ttaagcgtcg catcaggcat tatggcgcag ttgccggatg cggcatgaac gccttatccg
    25621 gcctacggga acagtgctct ttgtaggcct gataagacgc gttaagcgtc gcatcaggca
    25681 acaaactcac gggtgagcca caaaccggga aagccgctgg cgcagcaggc ggttttcctg
    25741 cttcaggtgc gcaatatcat ccattaacgt cagcgccacc gcgatccccg gccagtccag
    25801 agccagttca tgacgcaggc gtaccgcgcg ttgcaccaca atggcggcat ggtcgtcaaa
    25861 tacccaggtt gtctcctgga tctcactcgg ttcaaccacc cccaaaccga caatttcatt
    25921 caactcctct tcagagatgc cggtatgcag gcaaaattcg gtaatagtaa aagtcaccgt
    25981 aacattagcc attatgcttt cccccaatct ttacgtggat caaaagacga ctgggcgtct
    26041 gccagttgct gccacagcgc ggcagtgttt tcatccggtt tcggcggcat cacgattttc
    26101 agtaccgcat acagatcgcc ggtctgtttt ttgctcacca gacctttgcc tttaacgcgc
    26161 aatcgttgcc cggcctggct gccaggcggg atagtcagca aaatgctttc tttcagtgtt
    26221 ggaacggtga ctttagtacc cagcgccgct tcccacgggc taaccggcac cactatttcc
    26281 agatcctggc cgacaatatc aaacagcgga tgtggcgcaa tgtgaatcac cagccacagg
    26341 tcgccatttg gaccgccgtt ttcgcccggc gtcccctggc ctttcaggcg gatgcgttga
    26401 ccattgccga cgcccgccgg gatcttcaca ttcagcgttt tcgggatttc ctgttcgatc
    26461 atgccaaagg cgttataaac cggcaggtta tagctgatgg tacgcttatg ctcagtaagc
    26521 gtttcttcga ggaaaaccgc cacttcgatt tcaatatcgt ggccgcgtgt ggcggggcgt
    26581 tgacggctct ggcgggcatg ctgaccgaaa attgacgaga agatatcgtc aaaatcttcg
    26641 gcgttaaaac tctgaccgtc gccatgatgg aactgacggt taaattgcgg atcgttgcga
    26701 tgttgccaca tctgatcata ctcagcgcga cgttgttcat cacttaacac ttcccaggct
    26761 tcggcgacct ctttgaagcg ggcttcggca tccggttctt tgctgacatc aggatggtat
    26821 ttgcgggcca gtcgacgata ggcggtcttg attgtcttga gatcgtccgt cggtttcacg
    26881 cccatgatgg cgtaataatc ctttaattcc atagcgttat ctcgcgtaaa tcaacacaaa
    26941 ttgaaggaac ccctgtaagg taactcctat aagtgtaggg taatcctcaa aatttcatat
    27001 gccaacacag aatatgttat tgaaatcatc gcggagggga ggttgcctca aggtgggagg
    27061 aacatatttt atttacctca ctcctgaact tttggctcat gcttacaagt taaacaataa
    27121 ggaaaggaat gcacaactcg actatttaaa tcgttatgca atttaatgat aaagacatgt
    27181 gctaaaaacc attgctatta gtctcacatt ctttttttat tggtaatggt aacgccgctg
    27241 attttcttta tagctactga tgtaatcatt agcggcgtaa acgaggccgg ggctaatcag
    27301 gcatagtttg cgtcaaaact tgcctgtttt taaaggggaa tatagaaaaa caggcgttca
    27361 acgagccatt ttgcgaacct gttcccggaa aaatgacata tttctgtcac actctttaat
    27421 tattgataac aaaagaggtg tgaggaatga acaaaacgct aatcgccgca actgtggcag
    27481 ggatagtttt actcgcttca aatgctcagg cacaaaccgt accggaaggc tatcagctac
    27541 agcaagtcct tatgatgagc cgtcataact tacgtgcgcc gctggcgaac aatggcagtg
    27601 tgctggagca gtcgacgccg aataaatggc ctgaatggga cgtccccggt gggcagctca
    27661 ccactaaagg gggcgtgctc gaagtgtata tgggccatta tatgcgtgaa tggctggcag
    27721 aacaggggat ggtgaaatca ggggaatgcc cgccaccgga caccgtttat gcctatgcca
    27781 atagtctgca acgcaccgtt gcgaccgcac agttcttcat taccggcgca ttcccggggt
    27841 gtgatattcc tgttcatcac caggaaaaaa tgggcactat ggaccccacc tttaacccag
    27901 tgatcaccga tgattccgcc gcattcagtg aacaggcggt ggcggcaatg gagaaagagc
    27961 tcagcaaact ccagcttacc gacagctaca agctactgga acaaatcgtt aactataaag
    28021 attctcctgc gtgtaaagag aagcaacaat gttcgcttgt agatggcaaa aataccttta
    28081 gcgcgaagta tcaacaagaa ccgggcgttt ccgggccgct gaaagtcggc aactcgctgg
    28141 tagatgcgtt tactttgcaa tactacgaag gttttccgat ggatcaggtg gcctggggag
    28201 aaatcaaatc tgaccagcag tggaaggtgt tgtcgaagct gaaaaacggt taccaggaca
    28261 gcctgtttac ctcaccggaa gtggcgcgca atgttgcgaa accgctggtc agttatatcg
    28321 acaaagccct ggtcactgaa cgcaccagtg caccgaaaat cacggtatta gttgggcacg
    28381 actccaacat tgcctctctg ttaacggcgc tggatttcaa accgtatcag ttgcatgacc
    28441 agaacgaacg cacgccgatt ggcggcaaaa tcgttttcca gcgttggcat gacagcaaag
    28501 ccaatcgcga tttgatgaaa attgaatatg tgtaccagag tgcggaacag ttacgtaatg
    28561 ccgatgcgtt aaccctgcag gcacctgcgc agcgcgtgac gctggaatta agcggttgcc
    28621 cgatagatgc caacggtttt tgcccaatgg ataagtttga tcgcgtattg aatgaagcgg
    28681 tgaaataaca gaaaactccc ccgcgtgaag cgggggagtc gctggttaaa cgtttttacg
    28741 ttcgatggtc tgttcgcccc aaaaaagcga atctttatcg gtcttagcaa aggctttgac
    28801 taacacttca tcgctacctt cttcccaaat cttttccgcc attttttcgt cgtacccggc
    28861 gacttcgaaa atggcctcgg ctatttccgg cgacgtattg cgcagagatg cccattcacc
    28921 gacgtgatga gctttcgctt cttgagttgg catgcgtatc ctcctgttga agattagccg
    28981 ttaagtttaa ctgccagacc tgcgacatat tccccttgat aacgagcaat agacagttct
    29041 tcctggctgg gctggcgtga accgtcaccg cctgcgatgg tggttgcgcc gtacggcgta
    29101 ccgccgcgaa cctgtgaaac gtcaaataat tcctgcgctg cgtagccaat ggggacaatc
    29161 accatgccgt gatgcgcaag ggtcgtccag gtggatgtga tggtttgttc ctgaccgccg
    29221 ccagtaccgg tggaactaaa gacgctcgcc agttttccgt atagtgcgcc ggaagcccac
    29281 aggccgcccg tctggtcgag gaaggtacgc atttgaccgg acatgttacc aaagcgggta
    29341 ggtgtaccaa aaataatggc gtcgtaatcg gccagttctt gcggggttgc aaccggtgca
    29401 gtttgcgttt taccgcctgc tttttcaaat aattgcggcg gcatggtttc cggtacacgc
    29461 ttaacgacaa cttctgcgcc atccactttg cttgcaccct cagcaactgc gcgagccatc
    29521 gtttcaatat gtccgtacat ggaataataa agcaccagaa ctttagccat ttctaaccac
    29581 tcctcgtgtt atctctattc cgtagcgatt cgctaccact tatttaaaga taagacgtcc
    29641 ttttcagagt gcaaatttca caaccactta tttgatttat aacaactttc acaagcacgt
    29701 aattttgtcg caaaatgaca catttttatc tcatcgcgtt tttttaatca taagagcggc
    29761 ttatggataa ttattggaga tgatatctat tctcgctaag aagctgttgc aggatattac
    29821 caaacgcgga tctgcccgcg tcagttcact aagcttagtt ccacgtagcg aaaatatggc
    29881 agccgccata cgccgcgtta attctatgca atatgatgtc tatacccaga cggaggtcag
    29941 taatggcaaa ccatcgaggc ggttccggca attttgcaga agaccgcgaa agagcatcag
    30001 aagcaggtaa aaaaggtgga cagcacagcg gaggtaattt caaaaatgac ccgcagcgcg
    30061 catctgaagc aggtaaaaaa ggtggcaaga gcagtcacgg taaaagcgac aactagccgg
    30121 gctaatcaat gacgcatgca tttttgtctg tagctcgtca aaacgccatc accgccggta
    30181 gccccggcgg ttttctgttt atggcttctg atgaacaact tctggcggtg gaacgtcaac
    30241 caaccttctg cttaacaacg cattgagtaa aatcgcgcca aaggtggctg taccgatccc
    30301 tcccaacgta aaaccgccca gtgtgagagc aaaatcaccc gcacccagca ctaaggttac
    30361 tgcgaccata atcaaattac cgttctggct taaatccaca ctgttttgta cccagatccg
    30421 tgcgcctgcg acggcaatca gcccgaacac aacaattgat gcaccaccaa tcaccgcagc
    30481 cggaatagta tggatcagcg cgccaaattt cggcgaaaag cccaacagca tggcgatgac
    30541 ggcagcggca acaaacacca gcgtcgagta gacttttgtc acggccatca caccgatatt
    30601 ctcggcgtag gtggttatgc cgctaccgcc gacagagcca gaaagcatcg tcgccagccc
    30661 atcgcctacg aatgcccgcc ccatatacgg gtccatattg cgtccggtca tcccggcgac
    30721 cgccttgaga tgacctaagt tttccgccac cagaatcacc gccacgggcg caatcagcat
    30781 cattgcctga ccattaaaag caggagtgga aaaatgtggc agaccgaacc aggcagcatg
    30841 gctgacgaga gtaaaatcga cggcttttcc cagccctaaa acgttggtca tcacgccata
    30901 cagcagacag gcgacaatta atcctacgag aatcaataat cgctggatca tgccacgggt
    30961 aaatacggcc accagcccaa tacacagcac cgtcattacc gccatccagc tatcaaaggc
    31021 cgaagccgat acatttttca ctgcgatagg cgctaagttc aggccaatcg ccatcactac
    31081 cgcacccgtc acaaccggcg gcattagtcg ttcaatccag cgcgtaccga ttttcatcac
    31141 caccaggcca atgacggtat aaaccagccc acaggcgata atcccgccca gcgcgatgct
    31201 gatgttcgga ttaattccct gaccattaaa gcccgtcgcg gcaatcacca cgccgacaaa
    31261 agccgcgctg gaaccgagat aactgggcac gcgcccgccg gtaataaaga aaaacagtaa
    31321 cgtgccgatc cccgacatta aaatggaaag attgggatcc agccccatca gaatcggcat
    31381 taacaccgtc gcgccaaaca tcgccaccgc gtgttgaacg cccattactg ccgtttgagc
    31441 aaacggcaat cgttcgtccg gcgcgaccac gccgctctct gtagaggtcg attttaactg
    31501 ccagtgagga aaaccgaaca ttgccatcag ctgtctcctt aaggaggtta acaagcaggg
    31561 cgcatcagcg cgtgataact gcgatcgaac cacaccagcc cgtagggtgt ggcgtgacga
    31621 tgaatcgctt cgatggcgca aaacaaaatg tcgtgggtgc cgacgctcac cacctggctg
    31681 atacggcagt caaacgaaac cagtgccttt tccagttgcg ggcatccggt cacaccagtc
    31741 tgccagcggg cggcggcaaa gcggtgttcc atgggcgttt tgccgccaaa aaggtttgaa
    31801 agcggctcct gcccggcgct aagtgtattt acacacagcg ttcgattttc attgaatacc
    31861 ggccagacgg acgccccacg attcaggcac accagtaatg tgggcggcgt gtcggtcacg
    31921 ctgcagacgg cgctggcggt gaacccggcg cgcccggctg gaccgtccgt agtgatgata
    31981 ttgaccgccg cgcccataca ggacatcgca tcgcgaaagg tttgttgatc gacaatgttc
    32041 attgtttgct ccttacaaca gcccgcaggc ttcttcaaag gacagacgtg gcaggcgcgc
    32101 aaaaagtttg ctggaatcgc catagccgat attaatcagc agatcgctct tcagcgtgct
    32161 gcccgcaaaa aaggcgtcgt caacgtattg acggtcaaag cccgacatcg ggccggtatc
    32221 cagccccagc gcacggcagg cgacgatcag ataggccgcc tgcatggaac tgttgcgaaa
    32281 cgctgtttct tcggcaagtt gtggactgga ggtaaaccaa ctgcgggcat cgccgtgagg
    32341 aaacagctgt ggtaaccgtt cataaaattc actgtcccag gcgacgatag cggtgacggg
    32401 cgcggtcagg gttttttgca gattgccgct ggaaagcgcc gggcgcagac gttcttttcc
    32461 ttctgcagtg cggataaaca cgatccgggc cggagaacag ttagctgatg tcggccccca
    32521 tttcatcagg gcataaatct cccgtaacgt ctcatcgctg acggggggct cccgccagcc
    32581 gttgtgagtg cgggcatcgg tgaacagggt gctaagcgca cctgggctaa cggcttcgtt
    32641 catagcaatt ccttacagag cggcttcacg gtgatgtaac aggctggcaa gcccgttgag
    32701 taacagagca ttaaacgttt cgggatcggt cacgttgcag gcgtgtccgc catagcgcat
    32761 caccattttc tggctatcgg gcagggcggc atgaagttca ctggaacatg ctgttggcac
    32821 cagcagatcg tcactggcgc agatgatttg caccgggcag cggatacgat ccgcatggtg
    32881 actaaagtca gcgcgtttga gggcgttaag tcgacgcagt aaattatttt tgccctgaaa
    32941 atgcgccagt gccagcgcat cttctgcctc aaggcgaggt gcgcgggccg ccatccagtc
    33001 ggcgggatag aggaacaacg gctgcgcttc cacccatgcc tgcgcgccgc cgctatgtag
    33061 taactgttcg cgaacctgaa aacagcggcg cgtatgggtg tttattcgta gccagccgtt
    33121 aacgctgacc agcacagtta ccgacgcggg ataatccagc gccagctgca ttcccaccag
    33181 cgcaccgagc gcatggccga ccaccgcgta acgctcaatc cctgcggcta ccagcgcctg
    33241 atgcagttcc gctgccatct gggcgatact gtaatcttct gccagcgtgt cgggattatt
    33301 gccggtgccg cgctggtcgt aacagactac ctgatactcc tgatccagca ccgccagttg
    33361 cggtaaccag taactgccgc taccgccaag acccgaaatc aacaccacta cgggcgcatc
    33421 agcataaggg ggaggtgaga gtgaaagttt catcgcggcc tcacttggcg atatgcgcaa
    33481 ttgtggcgat ttccaccagc gcgtcaggtt ttaccagtcc gcactgaatg cagaatcgcg
    33541 ccggtttgtc acccgggaaa aactcggcgt agatttcgtt aatcgcggcg taatttttcc
    33601 agtcggtaat aaagatgctg ttgaaagtca catccgccat cgtgccaccc gccgtctcga
    33661 tgaccttgcg gatggtttcc agaacgtggc gggtttgcgc ctttgggtca tcggcaaaca
    33721 gcacgttgtt atgttgatca aaagccagcg taccggagac atacaccacg ccatcagcca
    33781 gcgtgccggg aacgaagggg gccagcggtg cgctgctgcc agcaggaata attacggatt
    33841 ttggcatcgt taaactcctt aagcgatacg agcaaaggac gtggaagaaa gcgcgtcgca
    33901 gaacgtttcg acgtcgctga cccagccaaa aaaggtttcg atattgaaca acgcagcttt
    33961 ctgtgcaaat tccggccccg cctggtgtgt tgcgtcttcc agcaccacgc cgaaatactc
    34021 cagaaaaaag ccgtcgcgta gcgtcgattc gacgcagacg ttggtagcga taccggtgaa
    34081 aaccagatgg cgtattccac ggctgcgcaa aatgctgtcc agcggcgtat tgaagaaacc
    34141 gctgtagcgc ggcttcggca gcacaatatc gccaggctgc ggcaccagtt catccaccag
    34201 ttgataatcc caggagcctt tcgccagcaa tttcccctgc agctgcggct gcttacgcat
    34261 ggttttcagg gcgttcgatt tatgaaaatt cggtgagccg gggccgccag cctcgacata
    34321 ctgttcatcc cagccatttt gaaaccagat gatcagcatc cctgccgctc gcgctgcggt
    34381 cacggcggtt tgaatgttgg caatgaccgg gcgagtggtt gagacatcaa acccggcgag
    34441 atctaagtag ccgcctggcg tggcataagc gttttgcata tccaccacga tcagcgcact
    34501 ttgctgcgga tcgaaggtaa tggcttccgg tcgagcggtt aaggtcgtca tcatgccacc
    34561 tcctgagtca gcgcagggag atgggcgcgg cactgcatca gtggttgaat gcgctcgccg
    34621 aaggtttcga ttcccgacag aaaatcatcg aaggtcaaca gcacgccttc ggcaccaggc
    34681 acgtttgcga cttcatctaa catgcgcgcg acactggcgt aagaaccgac taacgtcccc
    34741 atattgatgt ttaccgccga agtgggatcg gccatctgac ggacgttggt gtcagtacct
    34801 gagcgggtat ctttctgact ttgttcggtt agccagctta acgcctcttc atccgcgccc
    34861 gctttgtagt gttcccattt tgcacgagcg gcatcgtcgg tttcgtcggc aatcaccata
    34921 aacaacacat aagagccaac gtcgcgtccg gtttgctctg cggcctgttt catccgcgca
    34981 gcggtcgggg cgaaagccgt gggtgtattt acgcctttgc cgaaacagaa gttaaaatcg
    35041 gcataccggg cggagaacgc catgccagcg tcgctttgcc cggcgcagat cactttcatg
    35101 gggacactcg gttgcggact gacgcgacaa tcatccatag tgaaaaaatc gcctttaaaa
    35161 tcgcttttcc ccgagcccca caggtcgcgc agcacctgaa catattcggt gagatagtcg
    35221 taacgacggg agaaatagtc atcgccaggc cagatcccca tctgctcata ctcgggcttc
    35281 tgccagccag tcacgaggtt gacgccaaaa cgcccgccag agatggagtc gatggttgcg
    35341 gccatacggg cgacgattgc cggaggtaac gttaaggtgg cagctgtcgc gtatatctga
    35401 atgcgcgagg tcacggctgc cagccccgcc atcaaggtga acgactcaag gttgtgatcc
    35461 cagaactcag ttttgccgcc aaagccacgc agtttgatca tcgacagggc gaaatcgaaa
    35521 tggtagtgct ccgctttttg cacaatggct ttattcagtt caaatgtcgg catgtactgc
    35581 ggcgcgtggg tcgaaatgag ccagccgttg ttgccaatag gtacgaatac gccaattttc
    35641 atcatcaacc tctcttcgtc tcgtaaagtg aaagtcagac ggggcgctgc atcctgcata
    35701 tccttttcag ccgcgtaatg gcttgtttgc aaagcggatg ccagttttta aaaagtgaat
    35761 gttattaatg tgttaatgtt aagttgtcta aaatgcctga aaaaaagtgg actaaacggt
    35821 caaaacagtt gcacataaaa catgcattcg tgcgcgatga gagtgcagaa ggtcgaggcc
    35881 gggcgggggt tttgctatcc tgttgccaat ctacaagagg ggagagcgca tgacgcaagg
    35941 cgcagtgaaa acaacgggta aacgttcgcg cgcagtgagc gcgaagaaaa aagcgattct
    36001 tagcgcagca ctggacactt tttcacaatt cggttttcac ggcacaaggc tggagcagat
    36061 cgcggagttg gcgggtgttt caaaaaccaa tctgctgtat tactttccgt caaaagaggc
    36121 gctgtatata gccgtactgc ggcagattct cgatatctgg ctggcaccgt taaaagcgtt
    36181 tcgagaagat ttcgccccgc tggcggcgat caaagagtac atccgtctga agctggaagt
    36241 ttcccgcgat tatccgcagg cttcgcgcct gttctgtatg gagatgctgg caggtgcacc
    36301 gctgttaatg gatgaactga cgggcgattt gaaggcatta attgatgaga aatcggcgct
    36361 gattgccggt tgggttaaaa gcggcaaact cgcgccgatt gatccgcagc atttgatttt
    36421 tatgatttgg gcttccactc aacattacgc cgattttgcc cctcaggtgg aggcggtgac
    36481 aggcgcgacg ttgcgcgatg aggtattttt caatcaaacg gttgaaaacg tgcagcggat
    36541 tattattgag gggattcgac cacgctaatg gtgccggagg aaggtgtaac atcctccggc
    36601 tacctgttta accgatcgtc attaaactgg cgttaccgcc agcggcagcg gtattcacac
    36661 tcagcgaacg ctcgatatac agccgttcca gaaggatatt gctttcgcca cgggcaaaac
    36721 cctgcaccga aacaattgca ccatcccgcg cggcaacggc ttcacacaat gcgcgaagct
    36781 gatccgaatc accgtggaag atcaccgcat caaatggttg agcggttata ttttccgctt
    36841 tcgccagttg aatacgttcg ctgactgccg atggcaatgc cttcactaac tgacgatgca
    36901 gcgcattatc cggccacagc acctggctac ccaccgccag cacggcggcg agctgagtca
    36961 gcgcatcctg ttcatcatcc gcaatacaca acacgcgctc acgcggcagc agcgtccagg
    37021 tgttgcgttc acccgtcggc cctggcaaca atcgttgtgt tcctgcctgc gccaactcgc
    37081 catattgcgt acataacgcc tgcaattctg gacggtttgc cgcccattcc cgcagtgcat
    37141 ttagcggctg agtcaatgcg gctttcaact gcgcatcgac cggatactcc gcatcctgac
    37201 gcgcgagcgt caccgccagc gcactttccg ggcgattcgc cagcagacgg tagagataga
    37261 gcggaccgcc tgctttcggc ccggtgccgg acaatccttc gccgccgaac ggttgcaccc
    37321 caaccactgc gcccaccata ttacggttaa cgtacagatt accgacatgc gccgagccag
    37381 tgacctgggc gatggtttca tcaatgcgcg tatggacgcc aagcgtcaga ccataaccgg
    37441 aagcgttaat ctgctcgatc agctctggga gctggttacg gttgtaacgc accacatgca
    37501 acaccggacc aaagacctct ttttgtaatt cggcaaagtc atccagttcg atcagcgtcg
    37561 gagcgacaaa ggtgccgctt tgccattcac gggcatcttc gctgttttcc cgcaccgcct
    37621 ggaacacctg acggccttta ctacgcatgg tctgaatatg acgctcgata ttggctttcg
    37681 cttcgctatc aatcaccgga ccgatatcgg tggtcaggcg acccggatta cccatccggc
    37741 attcggccat tgcgccgcgc agcattttca gcgtgtggtc ggcaatctca tcttgcaggc
    37801 acagcacgcg cagtgccgaa caacgctgac ctgcactgtc gaacgccgag gccagcacat
    37861 ctattacgac ttgttcggtc agtgctgaag aatcgacaat catcgcgttc atgccgccgg
    37921 tttcagcgat gagcggaata gggcgaccct gagcgtccag gcggctggcg atattgcgct
    37981 gcagtaacgt agcgacttcg gttgaaccgg taaacatcac cccgcgcacg cgatcatcac
    38041 ccgtcagttg cgcgcccacg gtttcacccc gacctggcag caattgcacc acgcctggcg
    38101 gtacacccgc ttccagcaaa atggcgatcc cttgcgcggc aatcagcggc gtttgttctg
    38161 ccggttttgc cagcacgctg ttacctgccg ccagtgcggc agcgatctgt ccggtgaaaa
    38221 tagccagcgg gaagttccac ggactgatac ataccacagg ccctaatgga cggtgggttt
    38281 cgttagcgaa atcatcccgc acctgtccgg catagtagtg gagaaaatcg accgcttcgc
    38341 gcacttcggc aatggcgtta ctgaaggttt ttccggcttc acgcaccaga ataccaatca
    38401 gttgctgcat ctggctttcc attagcacgg cagcgcgatg caaaattgcc gcgcgttcag
    38461 ccggaggagt ggcaaaccag attggcgcgt tattaaccgc actttccagc gcctgttcta
    38521 cttcacgcgg cgtggcttca cgcacatagc ccacaatatc tttcggttcc gcagggttaa
    38581 taacgggcga catctcacct gccgctaccg gttgttccag cattggcaag gactgccatt
    38641 tttgcagtgc actattgagc agggctgaag agagcgaggc cagacggtgt tcgttagcga
    38701 gatccagccc tgccgagttg tcgcgcccgt gaccgtaaag atcgcgcggc aggggaattt
    38761 tcggatgcgg taatccagtt tgcccttcct gttgcgccag tttttctaca gcagtgactg
    38821 gatcggcgac cagttcatcc agtggcaaag aggtgtcggc aatacggtta acaaacgagg
    38881 tgttagcacc gttttccagc aggcggcgca ccagatatgc cagcagcgtt tcatgtgtac
    38941 cgaccggagc ataaatacga cacggacggt taagtttgcc gtcggcaact ttcccggtga
    39001 cctgctcata cagtggctcg cccataccat gcaggcactg gaactcgtac tgacccgggt
    39061 agtagttttg acccgccagt tgataaattg ccgccagcgt atgggcgttg tgcgtcgcga
    39121 actgcgggta gattagattt ggcaccgcca gcagtttttt cgcacaggca agataagaaa
    39181 cgtcggtata caccttgcgg gtataaaccg gataaccttc aaggccgtcc atctgtgcac
    39241 gcttgatttc actatcccag tacgcgcctt tcaccaggcg aatcatcaga cggcgacggc
    39301 tgcgggtggc gagatcaatc aggtaatcga tcaccaacgg gcagcgtttt tgataagcct
    39361 gaataacaaa accgatgccg ttccagcctg ccagttcagg ctcgaaacag agtttttcca
    39421 gcagatcgag ggagatctcc aggcgatcgg cctcttcggc atcgatgtta ataccaatat
    39481 cgtactgacg cgccagcagg gtgagtgatt tcagacgcgg gtaaagctct tccattaccc
    39541 ggtcatactg ggcgcggcta taacgcggat gtagcgccga cagcttgatt gaaatgcccg
    39601 gaccttcata gatgccacga ccgttagacg ctttaccaat ggcgtgaatc gcctgctgat
    39661 aggaaaccat atacgcctgt gcgtctgcgg cagtcagtgc ggcttcgccc agcatatcgt
    39721 aagagtaacg gaaacctttc tcttccagtt tgcgggcatt ggctaacgct tccgcgatgg
    39781 tttcgcccgt gacgaactgc tcgcccatca ggcgcatcgc catatccaca cctttgcgga
    39841 tcagcggttc accgctctta ccgataatgc ggttcagcga gcgggagagg ctggcttcgt
    39901 tatgggtgga aaccagtttg ccggtaaaca gcagccccca ggtagcggca ttaacaaaca
    39961 gggacgggct acgaccaatg tgtgactgcc agttaccgtt actgattttg tcgcgaatta
    40021 acgcgtcacg ggtggctttg tcgggaatac gcaacaacgc ttccgccaga cacatcagcg
    40081 ccacgccttc ctgcgatgac aacgaaaact cctgcaataa cccctgaacc atacctgcgc
    40141 gaccactggc gtttttttga ttacgcagtt tatcggccag ttgatacgcc agtttgtgcg
    40201 cctgttcagc aactggctgc ggcaggcgag cttgttccag cagcatagaa accgcttcgg
    40261 tttccgggcg gcgataggcc gcggtgatcg cggcgcggga aaccgactgg ggcaatattt
    40321 gttcggcaaa gtcgaggaaa ggctggtgtg gttcctctgc cggagtcggt gcttcatcgc
    40381 tctcattggc cgcgccagaa agcagcgcag gtagctccgg gagagtatcg ctgttttcca
    40441 gttgttcaag ataagaaaaa atcgcctgtt taattaacca gtgtggtgtg cgatcgatac
    40501 gtgtcgcagc agacttaata cgctcacgcg tcgcgtcgtc cagcttaacc cccatggtgg
    40561 tggttcccat gccattactc ctgttgttct gaaaggtgca acttaacgtt atcgtgaaat
    40621 atccatgatg ttgcaacttt gtgcaaccat gttaaatgtg acctgcgtag caagcttaaa
    40681 aatgaatgaa atgttaataa acgaaatcga tatgacaggg attaaaaaaa taactcagac
    40741 tttttctctg cggcagttaa catttttgaa aggtgcaacc gcaaaaaatg tgagagagtg
    40801 caacctgatg aaaaatagtg tcgctgagca ctaaaattta atgtaaatgg tgtgttaaat
    40861 cgattgtgaa taaccagcgc ttccggcagg atacggtcgc cctggtaaaa cataaactct
    40921 gttaccccgt tccggtggca gatataacgg caagtttcga cattgccgat aataattttt
    40981 tggagacttt agatggctat tagcacaccg atgttggtga cattttgtgt ctatatcttt
    41041 ggcatgatat tgattgggtt tatcgcctgg cgatcaacga aaaacttcga tgactatatt
    41101 ctgggcggtc gtagtcttgg gccattcgtg acggcattat cggcgggtgc gtcggatatg
    41161 agcggctggc tgttaatggg gttgcctggc gctgtttttc tttccgggat ttccgaaagc
    41221 tggatcgcca ttggcctgac attaggcgcg tggatcaact ggaagctggt ggccgggcgg
    41281 ttgcgtgtgc ataccgaata caacaataac gccttaacat tgccggatta tttcaccggg
    41341 cgctttgaag ataaaagccg cattttgcgc attatctccg cgctggttat tttgctgttc
    41401 ttcaccattt attgcgcttc gggcattgtg gcaggcgcgc gtctgtttga aagtaccttt
    41461 ggcatgagct acgaaacggc tctgtgggcg ggggctgcgg cgacgatcct ttacaccttt
    41521 attggcggtt tcctcgcggt gagctggact gacactgtac aggccagtct gatgattttt
    41581 gccctgatcc tgacgccggt tatcgtgatc attagcgtcg gtggctttgg cgactcgctg
    41641 gaagtgatta aacaaaagag catagaaaac gtggatatgc tcaaagggtt gaattttgtc
    41701 gccattatct cgctgatggg ttgggggctg ggttacttcg ggcagccgca catcctggcg
    41761 cgttttatgg cggcagattc tcaccacagc attgtccatg cgcgtcgtat tagtatgacc
    41821 tggatgatcc tctgcctggc aggggcggtg gctgttggtt tctttggtat cgcttacttt
    41881 aacgggcacc cggcggtagc aggtgcggta aaccagaacg ctgaacgcgt gtttattgaa
    41941 ctggcgcaaa ttctgtttaa cccgtggatt gccgggattt tgctgtcggc gattctggcg
    42001 gcggtaatgt caacgttaag ttgccagctg ctggtatgtt ccagtgcaat taccgaagat
    42061 ctatacaaag catttctgcg taaacaggcc agccagaaag agctggtgtg ggtagggcgt
    42121 gtgatggtgc tggtggtggc gctggtggcg attgcgctgg cggcaaaccc ggaaaaccgc
    42181 gtgctgggct tagtgagcta cgcgtgggca ggctttggcg cggcgtttgg tccggtggtg
    42241 ctgttctcgg tgatgtggtc acgcatgacg cgcaacggtg cgctggcggg gatgatcatc
    42301 ggtgcgctga cggttatcgt ctggaaacag ttcggctggc tgggtctgta cgaaattatt
    42361 ccgggcttta tcttcggcag tatcgggatt gtagtgttta gtttgctggg taaagcgccg
    42421 tcagcggcga tgcaaaaacg ctttgccgag gccgatgcgc actatcattc ggctccgccg
    42481 tcacggttgc aggaagggta agggaaggcg ttttaccgaa aatttcacgt cataacagga
    42541 agcaggcaga gggcaatcag tgattgccct ctgcgttttt tctcaaaata tttttacatc
    42601 ttctcatcat tatcactaca tttcacttgt atttttcttc atcgtaatga taatcgctat
    42661 cactgcgatt tacttttctt tgcatagatt gactaagaaa aacgtttaag ggtgggtggc
    42721 atgtttgttc cgtttctcat tatgttgcgc gaaggacttg aagccgcgct gattgtcagt
    42781 ttgattgcca gctatcttaa gcgtacccag cgaggccgat ggattggtgt aatgtggatt
    42841 ggcgtgttgc ttgccgctgc gttgtgcctg ggcttgggta tcttcattaa cgaaaccacc
    42901 ggcgaatttc cgcaaaaaga acaggaactg tttgaaggca ttgtggcggt gatcgccgtg
    42961 gtgatcctta cctggatggt tttctggatg cgcaaagtgt cgcgcaacgt caaagtacaa
    43021 ctggagcagg cggtcgatag cgcattgcag cgtggaaatc atcatggctg ggcgctggtg
    43081 atgatggtct tttttgccgt tgcaagggaa gggctggagt cggtcttttt cctgctggcg
    43141 gcatttcaac aagatgtcgg ggtctggccg ccgctgggtg caatgctcgg tcttgctaca
    43201 gccgtggtgc ttggcttcct gctctactgg ggcggtattc gcctcaatct tggtgcattt
    43261 tttaaatgga ccagtctgtt tattctcttc gtcgccgcag ggctggcagc tggtgccatt
    43321 cgcgcatttc atgaagccgg attgtggaac cactttcagg aaatcgcctt cgatatgagc
    43381 gcggtgctct caactcactc gctgtttggc acactgatgg aagggatttt tggctatcag
    43441 gaagcaccga gcgtcagcga agtcgccgtc tggtttattt atctcatccc ggcgctggtg
    43501 gcatttgttc tgccaccacg cgcaggggcg actgcgtccc gctccgtgta gcaaatacga
    43561 cgcaaactct tgcttagtta caacatactt taaagggata gtctcgtcat gaccattaac
    43621 ttccgtcgta acgcattgca gttgagcgtg gctgcgctgt tctcttctgc ttttatggct
    43681 aacgccgccg atattccgca agtcaaagtc actgtgacag ataagcagtg cgagccgatg
    43741 accattacgg ttaacgccgg gaaaacacag ttcattattc agaaccacag ccagaaggcg
    43801 ctggagtggg agatcctcaa aggcgtgatg gtggtggaag agcgggaaaa tatcgcccct
    43861 ggttttagcc agaaaatgac ggcgaattta cagcctggcg aatacgatat gacctgcggt
    43921 ctgctgacta acccgaaagg gaagttgatc gtcaaaggtg aagcaacggc ggatgcggcg
    43981 caaagtgatg cgctgttaag tcttggtggt gcaattactg catataaagc gtatgtcatg
    44041 gcggaaacca cgcaactggt gaccgacacc aaagccttta ccgacgctat taaagcaggc
    44101 gatatcgaaa aagcgaaagc actgtatgcg ccgacgcggc agcactatga gcgcatcgaa
    44161 ccgattgctg aactgttctc cgatctggat ggcagcattg acgcccgtga agatgattac
    44221 gagcaaaaag ccgccgatcc aaaattcacc ggtttccacc gtctggaaaa agcattgttt
    44281 ggcgataaca ccaccaaagg gatggataag tatgctgacc agctttatac cgatgtggtc
    44341 gatttgcaaa aacgcatcag tgaactggct ttccctcctt caaaagtggt cggcggtgca
    44401 gccggactga ttgaggaagt ggcggccagc aaaatcagcg gtgaagaaga tcgctacagc
    44461 cacaccgatc tgtgggattt ccaggctaac gttgaaggct cgcagaaaat tgtcgatctg
    44521 ctgcgtccac aactacaaaa agcgaatccg gaactgttgg caaaagtcga tgccaacttc
    44581 aaaaaggtcg ataccattct ggcgaaatac cgcactaaag agggttttga aaattacgac
    44641 aaactgaccg atgccgaccg gaacgcactg aaaggaccga ttactgcgct ggcggaagat
    44701 ctggcgcaac ttcgtggtgt gctggggctg gactaagcgt tatgcagtat gaagatgaaa
    44761 acggcgtgaa tgaaccgtca cgccgacgtt tactgaaagg gattggtgcg ctggcgctgg
    44821 cgggaagttg tccggttgct catgcacaaa aaacgcaaag tgcgccgggt acgctttcac
    44881 cggatgcacg caatgagaaa cagccgtttt atggtgagca tcaggcaggg atcctgacac
    44941 cacaacaggc tgcaatgatg ctggtggcgt ttgatgtgct tgccagcgat aaagccgatc
    45001 ttgaacggtt gtttcgcttg ttgactcagc gttttgcttt tctgactcag ggcggagcgg
    45061 caccagaaac gccaaatccg cgcctgccac cactcgattc cggcattctt ggcggctaca
    45121 ttgcgcccga taatctcacc atcacgttat cggtgggtca ctcattgttt gatgagcgct
    45181 ttggccttgc gccacagatg ccaaaaaagt tgcagaagat gacgcgtttc cccaacgact
    45241 cgctggatgc ggcgttatgt catggtgatg tgttgctaca aatttgcgcc aacacccagg
    45301 acacggtgat ccatgcgctg cgcgatatca tcaaacacac gccggatttg ctcagcgtgc
    45361 gctggaagcg ggaagggttt atttccgacc acgcagcgcg tagtaaaggc aaagagacgc
    45421 cgataaattt gctgggcttt aaagacggca ccgccaatcc cgatagccag aatgcgaagt
    45481 tgatgcaaaa agtggtgtgg gtgacggcag atcagcagga gcctgcgtgg acaatcggtg
    45541 gcagctatca ggcagtacgc ttgattcagt ttcgagtgga attttgggac agaacgccgc
    45601 tgaaagagca gcagacgata tttggtcgtg ataagcaaac cggtgcgccg ctgggcatgc
    45661 agcatgagca tgatgttccc gattacgcta gcgatccgga agggaaggtg attgcgctgg
    45721 acagccatat ccggctggcg aatccccgca cggcggagag cgagtccagc ctgatgctgc
    45781 gtcgtggcta cagttattcg ttgggcgtca ccaattccgg gcaactcgat atggggctac
    45841 tgtttgtctg ctaccaacac gatctggaaa agggcttcct gacagtacaa aaaaggttga
    45901 atggcgaggc gctggaggaa tatgtcaaac ctatcggtgg cggctatttc tttgcgctgc
    45961 cgggtgtgaa ggacgcgaac gattatctcg gaagcgcatt attgcgggtt taatgttttt
    46021 aggcgtataa ggcgtttacg ccgcaccagg cgttcgtgcg ctgatgcgac gcttgcgcgt
    46081 cttatcatgc ctacaatcgg tgcgggtcgg taggccggat aaggcgttca cgccgcatcc
    46141 ggcaagcttt taccagtacc gcgaatcctg ctgaaagcac acagcttttt tcatcactgt
    46201 catcactctg tcatctttcc agtagaaact aatgtcactg aaatggtgtt ttatggttaa
    46261 atataagtga atatattgtt gcaatgaatg cgaaatctgt tgtacttatt aagtagcagc
    46321 ggaagttccc ggcagtgata gtcagtcact atggagatcg cggatggtaa cgtcctgtac
    46381 tggacatgtt ttagagaatc agcgcgccac cactcgcgga gatttctcct ccggtagtca
    46441 tctcgtcact ttgtattttc aacctcatcc tttcttttca tgtgttaccg acgccgtaaa
    46501 cggtgcgcgt agccgttttt cggcatttta tccaaaagca aactatggct tacaaggaag
    46561 ccaaccctct gatgttcgtg cgcataatcg cgctgccaac ggcgcgtgtg atgaatacaa
    46621 acaactcaag gtgctctcca tgggaagaca aaaagcagtg atcaaagctc gtcgcgaggc
    46681 aaaacgtgtg ctgagacggg attcgcgcag ccataagcag cgtgaagaag aatcggtcac
    46741 ctcgcttgtg caaatgagcg gcgtagaagc cattggtatg gcccgcgaca gtcgcgatac
    46801 ctcgcccatc ctcgcgcgaa atgaagcgca attgcactat ctgaaggcta ttgagagtaa
    46861 gcagctgata tttgccacgg gtgaagccgg gtgcggaaaa acctggatca gcgcagcaaa
    46921 agcggcagag gccctgatac ataaggatgt tgacaggatt atcgtcaccc gtccagttct
    46981 gcaagccgat gaagatcttg gtttcttacc tggtgatatc gcagaaaagt ttgctcccta
    47041 ttttcgcccg gtctacgacg tgctggtccg tcgcttaggg gcttccttta tgcagtactg
    47101 cctgcgaccg gaaataggga aggtggaaat tgcgccgttc gcctatatgc gtggacgtac
    47161 ctttgaaaat gcagtcgtca ttcttgacga ggcgcagaat gtgactgccg cgcaaatgaa
    47221 aatgttttta acccgcctcg gggagaacgt gacggttatc gtcaacggtg atatcacgca
    47281 atgcgatttg cctcgcggcg tgcgctccgg attaagtgac gcgctggaac gtttcgaaga
    47341 ggatgaaatg gtcgggatcg tccgattcgg taaagaggat tgcgtacgtt cggcactttg
    47401 ccaacgtacg ctacatgcat acagttaagt gtattatcgg tgcagagccc gggcgaaccg
    47461 ggctttgttt tgggtgttta tacccggact agcgtttttt ctgaaaccac catttttatt
    47521 tgtccctggc tggtgaaatg tacgctcatc ctgtggcttt tttgtagttg ctgataaagc
    47581 tcatcaggta ttgctaagct ctctgcatat tcttgcggcg tatattggta tgctgcatga
    47641 tgctgctgtt tttgaaaacg cagcttattg tacaacgccc agacgattaa cacgacggca
    47701 ttcaccactg ccagcaaaaa atagaactga agtcggcttc tggcctcgct ttgccagaaa
    47761 taacccgtca gcagatcaat ggcgaataag aatatgaata aagcaaataa tgtccacaag
    47821 atagttgtgg caacataatc aaccagtaaa cgtactggcg attgtcgggt cgtaataatt
    47881 agattgttca tattaacctc tcagaatccc acgatcggga cttacccaac gagcgcgttg
    47941 ttttttaggc atcaacatga ctcgtgtaaa tgataccaac gtcgttgcca ggcttagcat
    48001 ccagaaaata accgggaacc aaataatcca gaaaagcgat gaagccagat tgtgctcata
    48061 gcgattctca atcaccagac tgacaataaa ttgcagtaaa cataacgtac acaataatat
    48121 tccggcagta tgtgtcgctg cgatatgtgt caattcaata tttaacggta cacctgcaag
    48181 ttgggctgcg taaataatga aaccgaccag gcaggtaaag gcccatattg tcgtcagaca
    48241 gtattcaaaa aacagtggcc acattcgaaa gttttctttg cgccacaacc ttgtcatatt
    48301 tttgaggaat acttctgcac cgccctgagc ccagcgcagg cgctgattcc acagcccttt
    48361 taacgtttca ggcattaata tccagcacag cgcccgtggc tcgtaaaaaa tcgtccactg
    48421 attcaactgc agcttccagc taatatcaat atcttcggtg atcatatcgt cactccagta
    48481 acccacttct gccagggcgc tgcgacgaaa tgcggcaata acaccggaaa cggtaaatac
    48541 gtttccatag atacgctggg tccgcttgat caaaccaata attgaggaat actcgccaac
    48601 ctgaatttta cccaccaggg tagaacgtgt gcgaatacga ggattaccgg ttacggcacc
    48661 cacacgcggg ttgtacaaca tcggttccac aatatatgcc gctgcatcgc ggtctaataa
    48721 cgcgtcgcca tcaatgcaca ccagatattc acttttcgcc gcggcagctc cggttttaag
    48781 cgcaatggct ttcccctggt tttgcgccag atgaatgacc cgcagacggg gaatttgtgc
    48841 agccatgcga tccaggatgg cacgggtttt gtctgttgaa ccatcattta cggcaataac
    48901 ttcaatgttc tcataacgct gtgctaaagc ggcatgtatg gtttcttcaa cgtttttctc
    48961 ctcattaaaa cagggaatga taatggagat agatggatta tctttcaact ggggggctgg
    49021 tgcgttttct ccccacggcc agtggcgttc acgatagacc cagaaataga cgccgccaat
    49081 aatccacata atggacataa aaaacggcca gaagaaaacg aacctcatca tcagttcacc
    49141 agagtgaaag tacgctacgc ataggggtat gcataacacc agacataata taaaaaacga
    49201 tacgatgcga ttaatcattt ttcggatacc aggctgttga aaactcagga cgaataacgt
    49261 ctatttcagg ttggttatgc agaaaattgt cgggataata accataattt ttcactccat
    49321 tcagttgtaa taggctcatc cagtgagcga gttgttgtga agaaatagcc tgatgctgac
    49381 catttttctg ccagttttgt gcctgtaatt ctaaaattga tttgtcttta gcctgcggga
    49441 tgcttttcat ctgattggtc aattgtatta accattgatc agccgatttt tctgtgacgc
    49501 cttccatata aggcatagcc ataatagcgg tccagtcata gctttttagg aaatcagcat
    49561 aattctgtgc aaaccaggct tcactttcag gttgtattac cggaagtgca aaaatatttc
    49621 gtgcagtttt aacatgtgga ccacgaatgg cttttacgcg cgcactaagt tctaaagtga
    49681 agtcagctaa cgcacgactt ttaaagcggg tccactgttt aaattgctcc gggttttgtc
    49741 gaatttcgct cagactcccg ctaaagccag cttgctgata agccgcgata gccgctgcac
    49801 tggcatcttc ataatctgaa agcaaagcat catcgtggaa caatatgcca tcaaaagcag
    49861 catgtccggc aagatcatca tataacatac caacttgtgc tctgaccctg tcatcgaaag
    49921 gagagagacg gcggtattgt tcaggatgaa tttgtgcttt tttctcccca gttggtaagt
    49981 attttactcg cgttaatgtg ggatctaaat cccagcttaa taccggcatc cacgcataga
    50041 tgtttacacc tgagcgggta cgcaattgcc aggcaacccg actaaaaata tctgctttca
    50101 ttggtagcaa acgatttgga aaccagacct ctttaaccag cccatcacca tcgggatcag
    50161 caaatgcttg caaatacacg gtagatattt gcatatcttt tacccgctga attagcacat
    50221 caatattgcg atccatttgc tggcggtttt cgtcataaac gtaatcaaga tcgatatgca
    50281 ttacccgttg tagtggtttt tcctgtacgg taataatttg ctgggcaaac tcttttaatg
    50341 agggattatt ggcgattaat actcgcggaa tggaatctaa ttgcgacgca tttgccaaac
    50401 ctgattcaag ggtgaagaac atgtcataac cgagtttttt taattccgct attgctatgc
    50461 cattcgcttc gccataaggc caaacaaaaa cgtgtggatt tacctcagcc tttgtacgca
    50521 ggtattccgt catttttaca gcatccaggc gaattctttc ccggtattct gctgcggttt
    50581 cataccgtgc gtggtcagta aaatatgcac gatttacata tgcaggcaat aagctgccgg
    50641 tggcattagc ctgaataccg tagtgagaat cccatgtatg agaagcgacc tcaacgagcc
    50701 gggaacgcgc aacttctcgc acttgttgcc acgtggcaaa atattctcga ctgaccatct
    50761 catcgccaaa tttcacttgt ttatccgctg gagtatcgac ccaactgccg acgggagccc
    50821 atacagccgg ccactggaag gcctgaagaa ttgggaagac acgggtataa aaactctggt
    50881 agccgtcatc aaaagtcagc actactgctt tttccggtag cggttttcct cctcgatgtg
    50941 cttcacgaat ttgagcaata ctgaccggtt gataaccgtt ctcgcgcagc caggcaaatt
    51001 gttcacgcag tgctgatgtt cgcactgaca taaaacgctg gtcggcagct tcgtcttcaa
    51061 cgttatgcca tgaaatcacc acaaaaccat tatgtggcca cggttgctcg gcgagtaaag
    51121 attcgcgatc ctgtggcggt ataaatgatg ttcttgactg gctaatgcac gcggtgagca
    51181 taattatact caccagcatc aggagatatt tatttccatt acgtaacata tttatcctta
    51241 aaatctgaat gtcatatcga attcaacgta taagttgtgt tctctgtcac cgtcataagg
    51301 tcgtttttcc cagcgtagcg ttgcgccagc atcaatcacg tcattccagc taatacgttg
    51361 cccgtagccg agttgggtga cgacatccgt gccataatgt ttttgccagg aggcaccaac
    51421 acctgcgctg aatatttgct cccagctatt ttcatagctt cgccataaca aatgacttgc
    51481 ctcaaatgcc ggaacaatat cgaacatttt tatagggttg tagtatgggg tgtcgtgttc
    51541 tgtattttgt tcgtaataca gattgggtag gaaatcgaca atcaaatatg gtgaagacca
    51601 gatgcgttct tgaccctcaa ttgagacttc atgacgctgg ttactgtcgg aaaaatcagt
    51661 gaaagcccag gagacaccgt acttacgccg ctcattttga taccagcgaa cataagcctg
    51721 tgcgctgttg cctgtaacac catttttcat tgcccgtaat ggaacgcggt gagagaggcg
    51781 ttccagttgc gaaccaatac gccagttatc attaaaatca taccagccag acaggcgcgc
    51841 gccgggttta tgctcatgat tgaaaaagcg ttcagcgtac tccgcctcga gccagatatt
    51901 acgtgaccgc cactcaacac ctgccagcca gtcgcgaaca atcccttttc cttcgctaaa
    51961 ttgtccatcg gcataaccga atccagcaaa accgcgccag ttatcattca gcggtggtga
    52021 ataaacgatg gtggttaagt cgacatcatg tttgccacta tctggacctt cggcatcaat
    52081 tcctgttgag ccagcgatac gaagctctgc aagattatgt acatcaaccg cacgttttaa
    52141 tcgtacaacg ccgggatctt gcggttcacg ttcgacaaca tcgtgggtta agacagctgc
    52201 ctgctgccat tcttgtaacg ttaatgctgt ccaggcttgt tcaacctcca gattaatatt
    52261 acgtggctcg atcacttctg ctttttttaa ttcattttct gccgcacgag gccaaccgcg
    52321 ggcttgtaac acactcgcgt aatcgatgcg cagtccctga tttcctggtg cgttataagc
    52381 aagttctctg gttgttattt cagcttgagg aagatcatta ctatattttg ctacggttga
    52441 gagaaacgaa tgcccctgta accaggtatc attcgggatg ctcgtaggcg tgcccattag
    52501 ccgaaggaaa ggcggcgaag tattaatggt atgtttggtg acagttagcg cgccgggata
    52561 attttcactc tccaggtggc tgtaaaagag atccgcaagt tcttcatcgg ataaatccgt
    52621 ggcaatggtt tccttgttat aaaagagctc ggtcattatt gactgtgctt ttttcggctg
    52681 ctgatctttg agataagccg acgcaaccca atatagcgcc cagggcggaa taatttgccc
    52741 cgtctttttt aaacgctgat agtgagaaat aacgtctcta taacgatcgc gagttaataa
    52801 cgcgccaaga tgatcaacct gaatacgctg gtactgggca gtgcggtctg ggttatcgtg
    52861 ccacagaatt tctaatgcag cgtattgggc gagggcgcga tcggcaatgg cataacgttc
    52921 attttcactg cgcgtaggca taaacgacag tctgaccagt tcggcatgaa tatcagcgcg
    52981 aatatctggc gttaaattgg catcgtcaat cgcggcagct agttgattat tacgtaatgc
    53041 cagcacgtat tctgtgggat attgttgctt agatgcattt tcaggtaatg actctgtcat
    53101 cgcccgtaat tcatcctgat aacgccccgt cagtttatag atataggctt ctgcgagtaa
    53161 attggctttg tccggtgctc cagatttaag ctgcttaagt ttaaacagcg cagtatcata
    53221 gtgacccgca tctgccaggg ttaaaatttg tccccgttga taatccttat tttgcggctc
    53281 cagagagagc gccttttgcc acagtgtaag cgagttttgc cattgttgca ggttacgata
    53341 agcgacggcg acagctgcat aaccacgcgc tggtaattgc tgatgacgat agcggttgta
    53401 aacggtaata acctgtttat cttgcccggc ccataaggca atctgtaacc agtcagcaat
    53461 ttggttatta ctgagtgttg atttttgtgc aaaccatgac aaagctggct gagtatttcc
    53521 tttgcgagct tcaataatca atgcatcata ggcgttatta acagcactct tcgccgcggg
    53581 actcgctgct aaaaatgcag cagtaagaat tttcaaagcc catttggttt tcgggcacct
    53641 ttttctgcta cttgaataca tcctgtatta ctccatgtat tgccaaaatc tctctctgta
    53701 tctaattaca ggtaactgaa aagaaagata tttttgcatc tcataatccg ttattaaacg
    53761 cggaagagag acgtgaattg ttgatgatga gaagaagaaa tgatgagcag agtgtccata
    53821 taaaatcctt ttctcgcccg aaaatccatt ccaatgatga ggatcttcag gaatacggc
//
LOCUS       DAFGPF010000019        51697 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFGPF010000019 DAFGPF010000000
VERSION     DAFGPF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 51697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51697
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.019"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(391..2964)
                     /gene="clpB"
                     /locus_tag="LSX49_001359"
     CDS             complement(391..2964)
                     /gene="clpB"
                     /locus_tag="LSX49_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL7167790.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
     gene            complement(3094..3825)
                     /gene="pgeF"
                     /locus_tag="LSX49_001360"
     CDS             complement(3094..3825)
                     /gene="pgeF"
                     /locus_tag="LSX49_001360"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HBL7167791.1"
                     /translation="MSKLIVPQWPLPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNP
                     DHVGENRKRLFAAGNLPSKPVWLEQVHGKDVLKLIGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGAEVREAFMAVDAKASTAFIQHGDKYLADIYQLARQRLASVGVEQIFGGDRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3822..4802)
                     /gene="rluD"
                     /locus_tag="LSX49_001361"
     CDS             complement(3822..4802)
                     /gene="rluD"
                     /locus_tag="LSX49_001361"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HBL7167792.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEEMRADFEEHKDEVDWL"
     gene            4937..5674
                     /gene="bamD"
                     /locus_tag="LSX49_001362"
     CDS             4937..5674
                     /gene="bamD"
                     /locus_tag="LSX49_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HBL7167793.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            5944..6285
                     /gene="raiA"
                     /locus_tag="LSX49_001363"
     CDS             5944..6285
                     /gene="raiA"
                     /locus_tag="LSX49_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBL7167794.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     misc_feature    6388..6513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            6389..6436
                     /gene="pheL"
                     /locus_tag="LSX49_001364"
     CDS             6389..6436
                     /gene="pheL"
                     /locus_tag="LSX49_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HBL7167795.1"
                     /translation="MKHTPFFFAFFFTFP"
     gene            6535..7695
                     /gene="pheA"
                     /locus_tag="LSX49_001365"
     CDS             6535..7695
                     /gene="pheA"
                     /locus_tag="LSX49_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HBL7167796.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELVVEVGKAKLLSHR
                     PVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPHWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQRQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHSLIMTRLESRPIH
                     GNPWEEMFYLDIQANLESAEMQKALKELGEITRSMKVLGCYPSENVVPVDPT"
     gene            complement(7738..8859)
                     /gene="tyrA"
                     /locus_tag="LSX49_001366"
     CDS             complement(7738..8859)
                     /gene="tyrA"
                     /locus_tag="LSX49_001366"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HBL7167797.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLILSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ"
     gene            complement(8870..9940)
                     /gene="aroF"
                     /locus_tag="LSX49_001367"
     CDS             complement(8870..9940)
                     /gene="aroF"
                     /locus_tag="LSX49_001367"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HBL7167798.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKTI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGQLTARVA"
     gene            10150..10515
                     /locus_tag="LSX49_001368"
     CDS             10150..10515
                     /locus_tag="LSX49_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HBL7167799.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     SAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWRKGADENASTIRLN"
     gene            10662..11180
                     /locus_tag="LSX49_001369"
     CDS             10662..11180
                     /locus_tag="LSX49_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HBL7167800.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPGLSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAIISGCNGFYFGNESP
                     TFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            11170..12396
                     /gene="dgcN"
                     /locus_tag="LSX49_001370"
     CDS             11170..12396
                     /gene="dgcN"
                     /locus_tag="LSX49_001370"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HBL7167801.1"
                     /translation="MMDNDNSLHKRPTFKRALRNISMTSIFITMTLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTHKEPGDTFSNFISHWLFPAPIIQPIRHNSETIGEVRLTARDSSISHFIWFSL
                     AVLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDA
                     RKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIEHASAENLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            12412..12894
                     /locus_tag="LSX49_001371"
     CDS             12412..12894
                     /locus_tag="LSX49_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBL7167802.1"
                     /translation="MIKHLLAPLIFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     VLSLKRANVVADAWAMGGQIPRSNLITQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(12971..13318)
                     /gene="rplS"
                     /locus_tag="LSX49_001372"
     CDS             complement(12971..13318)
                     /gene="rplS"
                     /locus_tag="LSX49_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBL7167803.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(13360..14127)
                     /gene="trmD"
                     /locus_tag="LSX49_001373"
     CDS             complement(13360..14127)
                     /gene="trmD"
                     /locus_tag="LSX49_001373"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBL7167804.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTYD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            complement(14158..14706)
                     /gene="rimM"
                     /locus_tag="LSX49_001374"
     CDS             complement(14158..14706)
                     /gene="rimM"
                     /locus_tag="LSX49_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBL7167805.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            complement(14725..14973)
                     /gene="rpsP"
                     /locus_tag="LSX49_001375"
     CDS             complement(14725..14973)
                     /gene="rpsP"
                     /locus_tag="LSX49_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBL7167806.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            complement(15110..16471)
                     /gene="ffh"
                     /locus_tag="LSX49_001376"
     CDS             complement(15110..16471)
                     /gene="ffh"
                     /locus_tag="LSX49_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBL7167807.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            16638..17429
                     /locus_tag="LSX49_001377"
     CDS             16638..17429
                     /locus_tag="LSX49_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417102.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HBL7167808.1"
                     /translation="MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVC
                     HAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIFQQLIS"
     gene            17450..18736
                     /locus_tag="LSX49_001378"
     CDS             17450..18736
                     /locus_tag="LSX49_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL7167809.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            complement(18790..19383)
                     /gene="grpE"
                     /locus_tag="LSX49_001379"
     CDS             complement(18790..19383)
                     /gene="grpE"
                     /locus_tag="LSX49_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBL7167810.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA"
     gene            19506..20384
                     /gene="nadK"
                     /locus_tag="LSX49_001380"
     CDS             19506..20384
                     /gene="nadK"
                     /locus_tag="LSX49_001380"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HBL7167811.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            20470..22131
                     /gene="recN"
                     /locus_tag="LSX49_001381"
     CDS             20470..22131
                     /gene="recN"
                     /locus_tag="LSX49_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBL7167812.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSQLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALETARALHQQRQHYANELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGYGHQHYFVSKE
                     TDGAMTETHMQSLDKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            22280..22621
                     /gene="bamE"
                     /locus_tag="LSX49_001382"
     CDS             22280..22621
                     /gene="bamE"
                     /locus_tag="LSX49_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HBL7167813.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(22683..22973)
                     /locus_tag="LSX49_001383"
     CDS             complement(22683..22973)
                     /locus_tag="LSX49_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HBL7167814.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDIVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(22963..23400)
                     /gene="ratA"
                     /locus_tag="LSX49_001384"
     CDS             complement(22963..23400)
                     /gene="ratA"
                     /locus_tag="LSX49_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010376629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HBL7167815.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTP
                     GQMTAAVDVSKAGISKTFTTRNQLTSNQSILMSLVDGPFKKLIGGWKFTPLSQDACRI
                     EFHLDFEFTNKLIELAFGRVFKELAANMVQAFTVRAKEVYSAR"
     gene            23571..24053
                     /gene="smpB"
                     /locus_tag="LSX49_001385"
     CDS             23571..24053
                     /gene="smpB"
                     /locus_tag="LSX49_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBL7167816.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            24268..24630
                     /gene="ssrA"
                     /locus_tag="LSX49_001386"
     tmRNA           24268..24630
                     /gene="ssrA"
                     /locus_tag="LSX49_001386"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            24859..26073
                     /locus_tag="LSX49_001387"
     CDS             24859..26073
                     /locus_tag="LSX49_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HBL7167817.1"
                     /translation="MYMSVFHNWLLDIASGNYFIYIKRLSANDTGATGGHQVGLYIPS
                     NIVEKLFPSINHTRELNPSVFLTAHVSSHDCPDTQARAIYYNNRYFGKTRNEKRITRW
                     GRGSPLQNPENTGALTILAFRLNEQNTDCSEVDIWVCVNPDEEDIIESAIGEIIPGTL
                     ISGPAGQILGGLSLQQTPVNHKYVIPEDWKKRFPSGNEIIQYAAGHYAKNSKDPDEQL
                     IDRRRVEYDIFLLVEELHVLDIIKKGFDSVDEFIALANSVSNRRKSRAGKSLELHLEK
                     LFIEHGLRHFSTQAVTEGNKKPDFLFPSAEAYHNVEFPVENLRMLAVKTTCKDRWRQI
                     LNEADKIHQVHLFTLQEGVSSAQYREMKDAGVRLVVPSTLHKKYPEAVREELITLGAF
                     ITELIELYAELS"
     gene            complement(26108..27511)
                     /locus_tag="LSX49_001388"
     CDS             complement(26108..27511)
                     /locus_tag="LSX49_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL7167818.1"
                     /translation="MLKEAEAEEKLRQENDKKLIEKVLEIYDQKYVAELLRKVGKNEW
                     SRETINRWINGKCLPKSLTSVEESLLRKMLPEPPANHPEYAFRFIDLFAGIGGIRKGF
                     EAIGGQCVFTSEWNKDAVRTYKANWFNDEQVHKFNLDIREVTLSDKTDVLETDAYAYI
                     DEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARIIRAKKPA
                     IFVLENVKNLKSHDKGKTFKVIMETLDELGYEVADAAEMGKNDPKIIDGKHFLPQHRE
                     RIVLVGFRRDLNIHKGFTLRDISRFYPEHRPSFGELLEPVVDSKYILTPKLWEYLYNY
                     AKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGEADFMNES
                     NQARRPRRLTPRECARLMGFEKPGGKPFRIPVSDTQSYRQFGNSVVVPVFEAVARLLE
                     PYILKAVSADAGKTGQP"
     gene            27948..28721
                     /locus_tag="LSX49_001389"
     CDS             27948..28721
                     /locus_tag="LSX49_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167819.1"
                     /translation="MDITEFPSGVIEHLGWYVYRLIDPRDGSTFYVGKGKGNRVFAHM
                     RGEVAATDDDELLSNKLKQIREIRLAGLEVIHVIHRHGMTDEKTAYEVEAALIDAYPG
                     LTNIMNGAGSNEFGAAHVKELIATYQPETITFHHKALMISVNRSAKDSELYDAVRFSW
                     RINVSRASQAEIILATVRGIVRGVFIADKWLKSTRENFPSLKYWDEDPDFEATQSSRY
                     GFEGREAPPEIANLYLGKKIPDELRKKGAMSPVRYSPNF"
     gene            complement(28791..29375)
                     /locus_tag="LSX49_001390"
     CDS             complement(28791..29375)
                     /locus_tag="LSX49_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBL7167820.1"
                     /translation="MAFRMSEQPRTITIYNLLAGTNEFIGEGDAYIPPHTGLPANSTD
                     IAPPDIPAGFVAVFNSDEASWHLVEDHRGKTVYDVASGDALFISELGPLPENVTWLSP
                     GGEYQKWNGTAWGKDTEAEKLFRIREAEETKNSLMQVASEHIAPLQDAVDLEIATEEE
                     NSLLEAWKKYRVLLNRVDTSTAPDIEWPEEPDTV"
     gene            complement(29375..32446)
                     /locus_tag="LSX49_001391"
     CDS             complement(29375..32446)
                     /locus_tag="LSX49_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001569831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HBL7167821.1"
                     /translation="MAVKISGVLKDGTGKPVQNCTIQLKAKRNSTTVVVNTLASENPD
                     EAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYEDSRPGTLNDFLGAMTEDDARPEA
                     LRRFELMVEEVARNASVVAQNTAAAKKSASDASTSAREAATHATDAAGSARAASTSAG
                     QAASSAQSATSSAGTASTKATEASKSAAAAESSKSAAATSASAAKTSETNAAASQQSA
                     ATSASTATTKASEAATSARDAAASKEAAKSSETNASSSASSAASSATAAGNSAKAAKT
                     SETNARSSETAAGQSASAAAGSKTAAASSASAASTSAGQASASATAAGKSAESAASSA
                     STATTKAGEATEQASAAARSASAAKTSETNAKASETSAESSKTAAASSASSASSSASS
                     ASASKDEATRQASAAKGSATTASTKATEAAGSATAAAQSKSTAESAATRAETAAKRAE
                     DIASAVALEDASTTKKGIVQLSSATNSTSESLAATPKAVKAAYDLANGKYTAQDATTA
                     QKGIIQLSSATNSTSETLAATPKAVKAANDNAEKRLQKDQNGADIPGKDTFTKNIGAC
                     RAFGGSVSTTTGNWTTAQFIEWLDSQGAFNHPYWMCKGSWSYGNNKIITDTGCGNIHL
                     AGAVIEIMGIKSAMTIRITTPTTSTGGGTTNAQFTYINHGTDYSPGWRRDYNSRNKPT
                     ASEIGALPSGGTAVSSVNLSSKGRVTALTDNTQGATGLELYEVYNNGYPTAYGNIIHL
                     KGMTAVGEGELLIGWSGTSGAHAPAFIRSRRDTTDANWSPWAQLYTSAHPPAEFYPVG
                     APIPWPSDTVPSGYALMQGQTFDKSAYPKLAAAYPSGVIPDMRGWTIKGKPASGRAVL
                     SQEQDGIKSHTHSASASSTDLGTKTTSSFDYGTKSTNNTGAHTHSLSGSTNAAGNHSH
                     RDGRRFNPSVFKDTYQYGYTSSGQNTWGVQGSVGMSTGWLANTSTDGNHSHSLSGTAA
                     SAGAHAHTVGIGAHTHSVAIGSHGHTITVNAAGNAENTVKNIAFNYIVRLA"
     gene            complement(32511..33110)
                     /locus_tag="LSX49_001392"
     CDS             complement(32511..33110)
                     /locus_tag="LSX49_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HBL7167822.1"
                     /translation="MRKVCAAILSAAICLAVSGAPAWASEHQSTLSAGYLHASMNVPG
                     SDDLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLQVTDNTGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAVDVAYEGSGSGDWRTDGFIVGVGYKF"
     gene            complement(33181..36678)
                     /locus_tag="LSX49_001393"
     CDS             complement(33181..36678)
                     /locus_tag="LSX49_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HBL7167823.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDTEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVGNLPPRPFNIRMRRMTRDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQHCDQSVPDGFGGTEPRITCNAWLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGIRTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGQGSPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSCTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVAADDGRERLVSTARTTETTYRFTQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVETSARYLGTALYWIAASINIKPGHDYYFYVRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLTEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKRLTAPTITSGGNP
                     PAFSLTSDGRLTAKNADISGSVNANSGTLNNVTINQNCTIKGMLEATQVRGDFVKAVS
                     KAFPKKVGTWGNTETPNGTVTVTISDDHNFDRQIIIPPIIFNGIAYDDPGSGNNPGGT
                     RYTGYGFEVRKNGVLIASRETKGAIPGSYSAVIDMPSGRGSVTLEFKIFQKGNQGAGN
                     ITDCTVIVTKKAASGISIR"
     gene            complement(36739..37347)
                     /locus_tag="LSX49_001394"
     CDS             complement(36739..37347)
                     /locus_tag="LSX49_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HBL7167824.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLSD
                     GWYQVRIAGRDAGENELSARLNEPLANGAVIHIVPRLAGAKSGGVFQVVLGAALIAVA
                     WWNPVGWLGAAAVSGMYAAGASMILGGVAQMLAPKARTPTAASTDNGKQNTYFSSLDN
                     MVAQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            complement(37284..38027)
                     /locus_tag="LSX49_001395"
     CDS             complement(37284..38027)
                     /locus_tag="LSX49_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7167825.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPE
                     DYFRMSPEDWLSAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDLHRGDDWWRHGQNLYLDNMEAT
                     GFYRVPLTEAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWHASAFTGICNDLVAVSTFV"
     gene            complement(38032..38730)
                     /locus_tag="LSX49_001396"
     CDS             complement(38032..38730)
                     /locus_tag="LSX49_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HBL7167826.1"
                     /translation="MQDIPQETHHETTRLTQSAQVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQAYPIQGTGFELNGKGSAARPTLTVSNLHGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            complement(38740..39069)
                     /locus_tag="LSX49_001397"
     CDS             complement(38740..39069)
                     /locus_tag="LSX49_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7167827.1"
                     /translation="METFHWKVRPDMNVVSEPKVVTVKLGDGYEQRRAAGLNNQLSIY
                     SVTIRVRKCEHPSLKAFLERHGGVRAFQWTPPYDWKPIRVVCRKWSASVGALWITITA
                     DFEQVVA"
     gene            complement(39069..42134)
                     /locus_tag="LSX49_001398"
     CDS             complement(39069..42134)
                     /locus_tag="LSX49_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL7167828.1"
                     /translation="MDQIANLVIDLGIDAAEFKNEIPRIKNLLNGAASDAERSSARMQ
                     RFMERQTQAARQTMQAASSAATAASVHAQTVEKSAQAHERMAREVEQTRQRMEALSQK
                     MREEQAQAMALAEAQDKAAAAFYRQIDSVKQASAGLQELQRIQQQIRQARNSGGIGQQ
                     DYLALISEVTAKTGVLTQAEAEATRQKVAFIRQLKEQATRQNLSSSELLRAKAAQLGV
                     SSAAEVYIRKMEQAGKATHSLGLKSAAARQEIGVLIGELARGNLGALRGSGITLANRA
                     GWIDTLMSPKGMMLSGVIGGIAAAVYGLGKAWYDGQKEGEEFNRQLSLTGHYAGVTAG
                     QLWTLSRAISGNGITQHAAAGALAQVVGSGAFRGNDIGMVARAAAQMERSVGQSVSDT
                     INQFKRLKDDPVNAAKALDNELHFLTATQLEQIRVLGEQGRSSDAARIAMSALAEETG
                     RRTADIDNNLNALGSTLKYLSDLWSRFWDAAMNIGREDSLDEQISALQEKVSRAKRLP
                     WTASSSQVEYDQQRLNELQEKKRQKDLQDAKEQAERNYQEQQKRRNAENAALNRMNET
                     EAARHQREIARINAMQYADQAVRDAAIQRENERYEKALASGKKKTRDPRNDEATRLLL
                     QYSQQQAQVEGQIAAARQSAGIATERMTEAHKQLLALQQRISDLDGKKLTADEKSVLA
                     RKDELIQALTLLDVKQQELQKQTALNELKKKTIQLTSQLAEEERAQRQQHDLDIATVG
                     MGDQQRQRYQVQLSLRQKYQQQLEQLRRDSEQKGTYNTDDYRKAEQALTESLNRQLNE
                     NRRYWQQLEVVQGNWKNGVLRAFQDFTVDADNTAGTAEQVFSSAFSNMGNGLATFVTT
                     GKLNFKSFTSSVLSDMAKILAQATMMKSIKGIGSVLGFDLSSLSLNANGGIYQSADLS
                     RYSGTVVNRPTFFAFAKGAGVMGEAGPEAILPLRRGADGKLGVVADIGGSGMAMFAPQ
                     YNIEINNDGTNGQIGPAALKVVYDLGKKAAADFMQQQARDGGRLSGAYR"
     gene            complement(42106..42435)
                     /locus_tag="LSX49_001399"
     CDS             complement(42106..42435)
                     /locus_tag="LSX49_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HBL7167829.1"
                     /translation="MQFVMRLAREFRRADWRRMLSEMSATELGEWGDYFRMQSFSDVW
                     MDAQFASLKALIVRMVSGSSDAAVADFSLLPEENGIPERTDEELMHLGEGISGGVRYG
                     PDSQPGH"
     gene            complement(42444..42830)
                     /locus_tag="LSX49_001400"
     CDS             complement(42444..42830)
                     /locus_tag="LSX49_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HBL7167830.1"
                     /translation="MFLKQGSFNYEKQSVVLSELSGLQRIEYLAFVQQRTAKFDAEEG
                     ELPEAERQIAFLRMGMDINAWLVSRSLWNAEQSQDVETLCASVITTWSYDALGAGAEM
                     VLSLSGMGAIENAGDLEHEVLTPEKS"
     gene            complement(42891..43634)
                     /locus_tag="LSX49_001401"
     CDS             complement(42891..43634)
                     /locus_tag="LSX49_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7167831.1"
                     /translation="MTTPNPLAKTKGAGTTFWMYTGKGDAFANPLSDTDWLRLAMVKD
                     LQPGEMTADAEDDTYLDDEDADWKTTTQGQKSVGDTSATLAWRPGDSGQKKLVQLFDS
                     GEVCAFRIKYPNGTVDVFRGWLSSLGKTIASKDVMTRTVKISGVGRPHLAEEGTETVS
                     VTGLTVAPASASVKVGATTTLTFTVKPDGASDKAISVHSTDPQTATVTLNGLVATVKG
                     VKQGSVSIVGMTSDGDFVAVAAVAVSAAG"
     gene            complement(43646..44047)
                     /locus_tag="LSX49_001402"
     CDS             complement(43646..44047)
                     /locus_tag="LSX49_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7167832.1"
                     /translation="MNRHTQIRQAVLARLREQCGDSATFFDGLPAFIDAQELPAVAVW
                     LSDAQYTGKMTDEDDWQAVLHIAVFIRAQAPDSELDMWMESTIFPALNDIPALSGLID
                     TLIPLGFNYQRDNEMATWAMAEITYQITYTN"
     gene            complement(44044..44622)
                     /locus_tag="LSX49_001403"
     CDS             complement(44044..44622)
                     /locus_tag="LSX49_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7167833.1"
                     /translation="MKGLENAIRNLNSLDTRMVPQASAWAINRVAQKAVSVATRQVAG
                     NTVAGDNQVKGIPLKLVRQRVRVFKASPSGKMTARIRVNRGNLPAIKLGTTQVRLARR
                     GGKLQYRGSVLKVGKYLFRDAFIQQLANGRWHVMRRIDGKNRYPIDVVKVPLSGPLTQ
                     AFEDARDRIIAAEMPKQLGYALKQQLRLWLTR"
     gene            complement(44634..44909)
                     /locus_tag="LSX49_001404"
     CDS             complement(44634..44909)
                     /locus_tag="LSX49_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA breaking-rejoining protein"
                     /protein_id="HBL7167834.1"
                     /translation="MSDPFSRLAARMDAITVRKMGKTASINDADMTVIPGETLAELNA
                     LSGPAVSLVVFSSGYRPRRGDRVVYDGQQWTVTRHERFNGKPMIFIE"
     gene            complement(44902..45225)
                     /locus_tag="LSX49_001405"
     CDS             complement(44902..45225)
                     /locus_tag="LSX49_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HBL7167835.1"
                     /translation="MAKNFVEEGKTVAIVASAAISSGDLVQVGDVFAVALTDIPQGET
                     GDGMTEGVFMLPKLKTDDMKTGKKVYLKSGKVQLTNSGSDPLVGVVWADAGTSAEEVP
                     VKLNV"
     gene            complement(45312..47339)
                     /locus_tag="LSX49_001406"
     CDS             complement(45312..47339)
                     /locus_tag="LSX49_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308856.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBL7167836.1"
                     /translation="MPQRNDRSRSTPTTSPKNNSWFRMQAGHQSDADIYIYDEIGFWG
                     VTAKQFISDLNALGDITHINLHINSPGGDVFEGIAIFNALKTHGASITVYVDGVAASM
                     ASVIAMVGNPVIMPENTFMMIHKPFGFTGGDAEDMRTYADLLDKVEAVLLPAYAQKTG
                     KTTDEIAAMLADETWMSGAECLAHGFADQVTPAVKAMACIQSKRTEEFKKMPESIRNM
                     ITPPRNSAPRVQDNEPEASRTPVQAAAPVVDENSIRAQVLAEQKARVNGINDLFAMFG
                     GRYQTLQAQCLADPECSLEQAREKLLNEMGRESTPSNKNTPAHIYAGNGNFVGDGIRQ
                     ALMARAGFEKTERDNVYNGMTLREYARMSLTERGIGVSSYNPMQMVGAAFTHSTSDFG
                     NILLDVANKAILQGWEDAPETYEQWTRKGQLSDFKIAHRVGMGGFSALRQVREGAEYK
                     YVTTGDKQATIALATYGELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAIL
                     TSNPKISTDNVSLFDKAKHANVLESAAMDVASLDKARQLMRVQKEGERHLNIRPAFVL
                     VPTAMESVANQVIRSSSVKGADINAGIINPVKDFATVIAEPRLDDNSQTTFYLAASKG
                     SDTIEVAYLNGVDTPYIDQMEGFSVDGVTTKVRIDAGVAPVDHRGLVKCTA"
     gene            complement(47284..48792)
                     /locus_tag="LSX49_001407"
     CDS             complement(47284..48792)
                     /locus_tag="LSX49_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL7167837.1"
                     /translation="MAILDDVIGVFSPGWKAARLRSRAVIQAYEAVKTTRTHKARREN
                     RTADQLSQYGAVSLREQARYLDNNHDLVIGVFDKLEERVVGKNGIIVEPHPVLRNGAI
                     ARDLAAEIRTRWSEWSVSPEVTGQFTRPMLERLMLRTWLRDGEVFAQMVSGRINSLTP
                     SAGVHFWLEALEPDFIPMTSDESNRLNQGVFVDYWGRPEKYLVYKSRPVSGRQMETKE
                     VDAERMLHLKFVRRLHQMRGTSLLSGVLIRLSALKEYEDSELTAARIAAALGMYIRKG
                     DGQSYEADGNGSKDKERELTIQPGIIYDDLKPGEEIGMVKSDRPNPNLETFRNGQLRA
                     VAAGSRLSFSSTARNYNGTYSAQRQELVESTDGYLILQDWFIGAVTRPMYRAWLKQAV
                     ASGVIRLPRDLDRSSLYTAVYSGPVMPWIDPVKEAEAWKIQIRGGAATESDWVRAGGR
                     NPDDVKRRRKAEIDENRKLDLVFDTDPASDKGGSSAATKRQEPQHTDDQSEE"
     gene            complement(48792..49004)
                     /locus_tag="LSX49_001408"
     CDS             complement(48792..49004)
                     /locus_tag="LSX49_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167838.1"
                     /translation="MNQNDIEAMIQRYTEAEMAVLDGKSVTFNGQQMTMENLSEIRQG
                     RQEWERRLAALITRRRGHPGYRLARF"
     gene            complement(49001..51103)
                     /locus_tag="LSX49_001409"
     CDS             complement(49001..51103)
                     /locus_tag="LSX49_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HBL7167839.1"
                     /translation="MLNQETAKAARTDSGYILRAPRRMRVADAVAQYMRVPMGAGNSV
                     PWDPLVAPYVIEPMNCLASREYDAVIFVGPARTGKTIGLIDGWVIYNVICDPADMLII
                     QMTEEKAREHSKKRLARTFRVSPEVVSRLSPNKNDNNVYDRTFLAGNYLKIGWPSVNI
                     MSSSDYKCVALTDYDRFPEDIDGEGDAFSLASKRTTTFMSSGMTLVESSPGRDVKDVK
                     WRRTSPHEAPPTTGILSLYNRGDRRRWYWPCPHCGEYFQPCGDVVAGFRDIADPVLAS
                     EAAYIQCPSCSGRIMPEQKRELNGRGVWLRDGESINADGSRYGDPRRSRIASFWMEGP
                     AAAYQTLSQLVYKLLTAEQEYETTGSEETLKTVINTDWGLPYLPRASMEQRKSELLEQ
                     RAEPVPSRSVPDGVNFLVATVDVQAGRHRRFVVQVTGYGSRGERWIIDRYNITQSLRG
                     DSDGESQRIDPASYPEDWDVLLTDVFHKSWPLASDPSQQMRLMAMAVDSGGEDGVTDN
                     AYKFWRRCRRDGLGKRIYLFKGDSIRRAKLITRTFPDNTGRTGRRAQAAGDVPLWLLQ
                     TDALKDRVNNALWRDSPGPGYVHFPDWLGSWFYDELTYEERSSDGKWSKPGRGANEAF
                     DLMVYAEALVILHGYEKIRWPDAPEWASRETWLECVPDSIEPSPSPEPVSTPVKKQKR
                     KKTVTDDVNPWLTSGGWL"
     gene            complement(51103..51597)
                     /locus_tag="LSX49_001410"
     CDS             complement(51103..51597)
                     /locus_tag="LSX49_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1441 family protein"
                     /protein_id="HBL7167840.1"
                     /translation="MDRELKNLTLNISQLAALSGVHRQTAAARLQNLPVAGGHESNLK
                     LYRVVDIVSAFLALPPPVAEGEMDAHERKAWYQSERERLKFEQETAQLIPASDVRREF
                     AIWAKAVVQVLETLPDILERDCGLQPAAVSRVQSIIDDLRDQIALRVTEAGADDEEEL
                     QQEE"
BASE COUNT        12346 a        14378 c        12125 g        12848 t
ORIGIN      
        1 tgagacttgg tattcatttt tcgtcttgcg acgttaagaa tccgtatctt cgagtgccca
       61 cacagattgt ctgataaatt gttaaagagc agtgccgctt cgctttttct cagcggcgcg
      121 gggtgtgcat aatacgcttt cccgctacag agtcaagcat ttatttttgc tttctctgcc
      181 ggaattctca ggagaacccc gctcacccgg cggcgtgttt gccgttgttc cgtgtcagtg
      241 gtggcgcatt atagggagtt attccggcct gacaagcgaa aaatataaaa actttatcgt
      301 tcgctcattt ttcaggcaaa acatcttaaa tatagtcttt tccgtctaac ttatagacaa
      361 aaacgagccc cgaagggctc gttttatcat ttactggacg gcgacaatcc ggtcttcatt
      421 aacttccagg cgaatcactt tacccggaac caattcacca gacagtattt gctgtgccag
      481 cgggttttca atctgctgct gaattgcacg tttcagagga cgtgcgccat agaccggatc
      541 gtaaccgttc tcgctcagca gtttcagcgc ctcgtcagaa atgtggattt cataaccacg
      601 ttcttccaga cgtttataca gacgtttcaa ctgaatctgc gcaatcgacg caatgtgctg
      661 ttcacccagc ggatggaaga ccaccacttc atcgatacgg ttaatgaatt ccggacggaa
      721 gttatggcta accacaccga gcaccagctc tttcatgtgc gcataatcca gttcaccgaa
      781 gcgttcctga atcaaatcgg aaccgaggtt agaggtcata atgacaaccg tattacggaa
      841 gtcgaccgtt ctcccctgcc cgtcagtcag acgcccatca tccagtacct gcaacagaat
      901 gttgaagaca tccggatgcg ctttttccac ttcatccagc agaatgacgg aatacggacg
      961 acgacgcacc gcttcggtca ggtagccacc ttcttcataa ccgacatatc ccggaggcgc
     1021 accaaccaga cgagacaccg agtgtttctc cataaactcg gacatatcga tacggaccat
     1081 cgcctcgtcg ctatcaaaca taaagttcgc tagcgcctta caaagctcag ttttccccac
     1141 accggttggg ccgaggaaca ggaatgaacc aatcgggcga tttggatccg ccagccccgc
     1201 acggctacga cgaatagcgt tagataccgc atcaaccgct tcgttctgac caataacgcg
     1261 atggtgcagt tcttgctcca tacgcagcag tttttcgcgc tcgctttcca tcatgcgaga
     1321 aaccggaatc cccgtccaac gcgccagcac ttcagcaatt tcggcatcgg tcactttatt
     1381 acgcaacaga cgcatagttt tgccttcgag ctgcgttgcg gcttccagtt gcttttccag
     1441 ttccgggatt ttgccgtatt gcagttcaga catccgcgcc aggtcaccca cacggcgagc
     1501 ctgttcaata gcaattttcg cctgttccag ttccgcttta atggtctgcg taccagaaag
     1561 cgaggctttc tctgctttcc actcttcttc taactcggag tactgacgtt ctttgtcgct
     1621 cagttcttcg ttgagcatat ccaggcgttt tttactggct tcatcagact ctttcattaa
     1681 cgcctgttgt tccagtttga gctggatgat acggcgatcg agtcggtcga gttcttctgg
     1741 ttttgagtca atctgcatac gaatgctgga tgctgcttca tcgatcaggt cgatggcttt
     1801 atccggcagc tgacggtcag caatgtagcg atgagacaac gtcgctgctg caacaattgc
     1861 cgggtcagta atttgcacat ggtggtgcag ctcgtaacgt tctttcaggc ctcgcagaat
     1921 agcaatggta tcttcaacag aaggctcggc aacaaacact ttctggaaac gacgttccag
     1981 cgcagcatct ttttcgatgt actggcgata ttcgtcaagc gtcgtggcac ctacgcagtg
     2041 caattcacca cgcgccaacg ctggtttcag catgtttccg gcgtccattg cgccatcggc
     2101 tttacccgcg ccgaccatgg tatgtaattc gtcgataaac aggatgacgt tgccttcctg
     2161 tttagcaaga tcgttaagta cgccttttaa acgttcttca aactcaccgc gatatttcgc
     2221 cccagccacc agcgcgccca tatccagcgc cagtacgcgg cggcctttca acccttcggg
     2281 cacttcgccg ttgataatac gctgcgccag accttcaacg atggcagttt taccgacgcc
     2341 gggttcacca atcaataccg ggttattttt agtacgacgt tgcagcacct gaatggtacg
     2401 gcgaatttct tcatcacgac caatcaccgg atcgagtttg ccttgttcgg ctcgttcggt
     2461 aaggtcgatg gtatattttt tcaaagcctg acgttggtct tcagcacctt gatcgttcac
     2521 gctttcacct ccacgcattt gttcaatcgc ttgagtaatg ttggcggtgg tcgcccctgc
     2581 tgctttcagg atgtcggcca gcgtgccgcg agactcaagt gccgccagaa cgaacagttc
     2641 tgacgagata aagttatcac cacgtttttg cgccagcttg tcgcaaagat taagaacgcg
     2701 caccagatcc tgtgatggct ggacatcacc accagtacct tcaacctgtg gtaaacgatt
     2761 taatgcctga ttgatatctg tgcgcaactg gccagcatta atgccagcgg atgttaataa
     2821 aggactaacc gaaccccctt cctgattcag cagggcgctc attaaatgaa gtggttcgat
     2881 gaattggttg tcgtgcccga gtgcaagtga ttgggcatcg gcaagagcaa gctggaattt
     2941 attagtaaga cgatccagac gcataactcc tcccataacg gatcaaagtt gctactggag
     3001 attaaatgag gtcatccctc aattattcaa ggttattgac cagattaatg tgaaaagaaa
     3061 atcacgcgta ccggatcgtc ttgattcttt aggttatatc agccaaatga aacttgccat
     3121 acgaccggtg gtcttgtcgc gacgataaga gaagaaagtc tcattttccg tatatgtaca
     3181 acggtcgccg ccgaaaattt gttcaacacc aacgctcgcc agacgctgcc gggcaagctg
     3241 ataaatatcc gccagatact tatcaccatg ctgaatgaaa gctgtactcg ctttggcgtc
     3301 tactgccata aacgcctcgc gaacctccgc ccccacttcg aacgcacgtg gcccaattgc
     3361 cggccctaac caggcgagaa tattttccgg attatcagca aaacaggaaa ccgtctcttc
     3421 caacacgcct gcgcacagtc cacgccagcc agcatgagcg gcggcgacct ccgttcccgc
     3481 acgattgcaa aacagcacgg gcaggcagtc ggcagtcatc actgcgcaaa ccgtgccagg
     3541 cgtattgcta taagaggcat ctgctcgttt tgaggcataa ggttcgccaa taagcttaag
     3601 cacgtctttg ccgtgtacct gctcaagcca gaccggttta gaaggcaaat tgcccgcagc
     3661 aaaaagtcgc ttgcgattct ccccaacgtg atccgggtta tcgccacaat gggcaccgag
     3721 gttgagcgag tcatacgggg gtaagctcac accgccgata cgggtagagc tacaagccgc
     3781 aacacctttt ggcagcggcc actgcgggac aatcagctta ctcataacca gtccacttca
     3841 tccttatgct cttcgaaatc ggcgcgcatc tcctcaatca gctccaccat atcttgtgga
     3901 ataggcgcat gccattccat ttcgatgccg gagatcgggt gataaagacg cagcatggtt
     3961 gcatgaagcg cctgacggtc aaacttacgc agcgtggaga taaacgcttc cgaagcacct
     4021 tttggcggac gcggacgtcc accataaacc ggatcgccca ccagcggatg agtgatatgg
     4081 gccatatgca cgcggatctg gtgcgtacgt ccggtttcca gacgcaaccg cagacgcgtg
     4141 tgcacacgga agtgttccat gatgcgatag tgagtgaccg ccggtttacc catgggatgt
     4201 accgccatgt gagtacgttt ggtcgggtgg cggctgattg gttcatctac tgtaccgcca
     4261 gcggtcatat gaccaattgc caccgcttca tactcacgtg taatttcacg ccgttgcaaa
     4321 gattcgacta aacgcgtctg agccggaacg gtttttgcca caaccatcag gccagtggtg
     4381 tctttatcca gacgatggac aatgcccgca cgcggtacat cggcaatggg cggataataa
     4441 tgaagcaatg cattcagtac cgtgccatcc gggttacccg cgccaggatg taccaccagg
     4501 tcgcgcggtt tattaataac gatgatatct tcatcttcat agacgatatc cagcgggata
     4561 tcctgcggtt caaaacgcgc ttcttcttca atctcagcgt tgatggcaac ctgctcgcca
     4621 cccaatactt tttctttcgg cttatcacac actttgccgt taaccagcac acgctggtcg
     4681 aggatccatt cttttatccg cgaacgtgaa taatccggga acatttcggc caaagcctga
     4741 tctaagcgtt gaccgagttg gttttcggac accgttgcag tgagctgtac tcgttgtgcc
     4801 atatatactg cttcttcgtt tatcgttggg gttttacggc tttgccgttt aatatagtgt
     4861 gctattgtag ctggtcttaa ccgggagcag gaacagagaa tctcccgtat tacattttga
     4921 ggaaagtcaa aacgtcatga cgcgcatgaa atatctggtg gcagccgcca cactaagcct
     4981 gtttttggcg ggttgctcgg ggtcaaagga agaagtacct gataatccgc caaatgaaat
     5041 ttacgcgact gcacaacaaa agctgcagga cggtaactgg agacaggcaa taacgcaact
     5101 ggaagcgtta gataatcgct atccgtttgg tccgtattcg cagcaggtgc agctggatct
     5161 catctacgcc tactataaaa acgccgattt gccgttagca caggctgcca tcgatcgttt
     5221 tattcgcctt aacccgaccc atccgaatat cgattatgtc atgtacatgc gtggcctgac
     5281 caatatggcg ctcgatgaca gtgcactgca agggttcttt ggcgtcgacc gtagcgatcg
     5341 cgatcctcaa catgcacgag ctgcgtttag tgacttttcc aaactggtgc gcggctatcc
     5401 gaacagtcag tacaccaccg atgccaccaa acgtctggta ttcctgaaag atcgtctggc
     5461 gaaatatgaa tactccgttg ccgagtatta tacagaacgt ggtgcatggg ttgctgtcgt
     5521 taaccgcgta gaaggcatgt tgcgcgacta tccggatacc caggctacgc gtgatgcgct
     5581 gccgctgatg gaaaatgcat accgtcagat gcagatgaat gcgcaagctg aaaaagtagc
     5641 gaaaatcatc gccgcaaaca gcagcaatac ataacagaaa cctgaaacac aaaacggcag
     5701 ccttgagctg ccgttttttt attctgttag ttgtgaaact gaagcgattt agtcactatc
     5761 gatctcatca aatatggccc gctttgagat attcctcaag taaaaaaaca cctcttcctg
     5821 cgatttctca caaaaaagat tcgttgacaa aaagtgacaa aattatgaga tttccatcac
     5881 acattttgac atcaggaacg ttatgctgaa ttcaccaaga cgggaagaca agaggtaaaa
     5941 tttatgacaa tgaacattac cagcaaacaa atggaaatta ctccggccat ccgccaacat
     6001 gtcgcagacc gtctcgccaa actggaaaaa tggcaaacac atctgattaa tccacatatc
     6061 attctgtcca aagagccaca agggtttgtt gctgacgcca caatcaatac acctaacggc
     6121 gttctggttg ccagtggtaa acatgaagat atgtacaccg caattaacga attgatcaac
     6181 aagctggaac ggcagctcaa taaactgcag cacaaaggcg aagcacgtcg tgccgcaaca
     6241 tcggtgaaag acgccaactt cgtcgaagaa gttgaagaag agtagtcctt tatattgagt
     6301 gtatcgccaa cgcgccttcg ggcgcgtttt ttgttgacag cgtgaaaaca gtacgggtac
     6361 tgtactaaag tcacttaagg aaacaaacat gaaacacaca ccgtttttct tcgcattctt
     6421 ttttaccttc ccctgaatgg gaggcgtttc gtcgtgtgaa acagaatgcg aagacgaaca
     6481 ataaggcctc ccaaatcggg gggccttttt tattgataac aaaaaggcaa cactatgaca
     6541 tcggaaaacc cgttactggc gctgcgagaa aaaatcagcg cgctggatga aaaattatta
     6601 gcattactgg cagagcgacg cgaactggtc gtcgaggtgg gaaaagccaa actgctttcg
     6661 catcgcccgg tacgtgatat tgatcgtgaa cgcgatttgc tggaaagatt aattacgctc
     6721 ggtaaagcgc accatctgga cgcccattac attactcgcc tgttccagct catcattgaa
     6781 gattccgtat taactcagca ggctttactc cagcaacatc tcaataaaat taatccgcac
     6841 tcagcacgca tcgcttttct cggccccaaa ggttcttatt cccatcttgc ggcgcgccag
     6901 tatgctgccc gtcactttga gcaattcatt gaaagtggct gcgccaaatt tgccgatatt
     6961 tttaatcagg tggaaaccgg ccaggccgac tatgccgtcg taccgattga aaataccagc
     7021 tccggtgcca taaacgacgt ttacgatctg ctgcaacata ccagtttgtc gattgttggc
     7081 gagatgacgt taactatcga tcattgtttg ttggtctccg gcactactga tttatccacc
     7141 atcaatacgg tctacagcca tccgcagccg ttccagcaat gcagcaaatt ccttaatcgt
     7201 tatccgcact ggaagattga atataccgaa agtacgtctg cggcaatgga aaaggttgca
     7261 caggcaaaat caccgcatgt tgctgcgttg ggaagcgaag ctggcggcac tttgtacggt
     7321 ttgcaggtac tggagcgtat tgaagcgaat cagcgacaaa acttcacccg atttgtggtg
     7381 ttggcacgta aagccattaa cgtttctgac caggttccgg cgaaaacgac gttgttaatg
     7441 gcgaccggac aacaagctgg tgcactggtt gaagcgttgc tggtactgcg caaccacagt
     7501 ctaattatga cccgtctgga atcacgtccg attcacggta atccgtggga agagatgttt
     7561 tatctggata ttcaggccaa tcttgaatca gcggaaatgc aaaaagcatt gaaagagtta
     7621 ggggaaatca cccgttcgat gaaggtattg ggctgttacc caagtgagaa cgtagtgcct
     7681 gttgatccaa cctgatgaaa aagtgccgga tgatgtgaat catccggcac tggattatta
     7741 ctggcgattg tcattcgcct gacgcaataa cacgcggctt tcactctgaa aacgctgtgc
     7801 gtaatcgccg aaccagtgct ccaccttgcg gaaactgtca ataaacgcct gcttatcgcc
     7861 ctgctccagc aactcaatcg cctcgccgaa acgcttatag taacgtttga ttaacgccag
     7921 attacgctct gacgacataa taatgtcggc ataaagctgc ggatcctgag caaacagtcg
     7981 cccgaccatc gccagctcaa ggcggtaaat cggcgaagag agcgccagta gttgctcaag
     8041 ctgaacattt tcttctgcca ggtgcagccc ataagcaaaa gtagcaaagt ggcgcagagc
     8101 ctgaataaac gccatattct gatcgtgctc gacagcgcta atacgatgca accgagcgcc
     8161 ccagacctga atttgctcca gaaaccattg gtatgcttcc ggcttacgtc catcacacca
     8221 gaccacaact tgctttgcca ggctaccgct gtccgggccg aacatcgggt gtaaccccag
     8281 caccgggcca tcgtgcgccg ccagcatggc ctgtaatggt ccatttttca ctgatgccag
     8341 atcaaccaga atacaatctt tcggtaaagg cggtaatttg ccgataactt gctcagtaac
     8401 gtggatgggc acactaacaa tcaccattcc ggcatcggca acaatatcag ccgctcgatc
     8461 ccagtcatgt tgctccagaa tccgcacctg ataacccgag agtatcagca tcttctcgaa
     8521 cagacgtccc atctgaccgc caccaccgac gataaccacc gggcgcagtg acggacaaag
     8581 cgttttaaat cctttgtcgt tttcactgga gtaagattca cgcatcaccc gacgcaaaac
     8641 atcctcaatc agatctggcg gtacacccag agcttccgcc tccgcacgac gcgaggccaa
     8701 catagatgcc tcgcgctccg gaacataaat aggcagtcca aatcggcttt tcacctcgcc
     8761 cacttcagca accaattcca gacgcttcgc taataaattc agcagcgctt tatcgacttc
     8821 atcaatttga tcgcgtaatg cggtcaactc agcaaccata ataaacctct taagccacgc
     8881 gagccgtcag ctgcccgttc agatcctgat gaatttcacg cagcaaggca tcggtcattt
     8941 cccagctaat gcaggcatcg gttacggata caccgtattt catttcactg cgcggttgct
     9001 cggaagactg attgccctcg tggatattac tttcgatcat cagaccaata attgagcgat
     9061 tgccatcttt gatttgagca accacggatt ctgccaccgc aggctgacgg cgataatctt
     9121 tattggaatt accgtggctg caatctacca tcagagacgg gcgcagtccc gcctgttcca
     9181 tctctttttc acattgcgca acatccgcag ggctatagtt tggcgcttta ccaccgcgca
     9241 ggatcacatg cccgtccgga ttcccctgag tttgtagcaa cgcaacctgc cctgcctggt
     9301 taatgccaac aaaacggtgc ggctgggcgg cggcgcgcat agcgttaatt gccgttgcca
     9361 gactgccatc ggtgccgttt ttaaaaccaa ccggcatgga aagcccggag gccatttcac
     9421 ggtgagtttg cgattccgtt gtacgagcac caattgctga ccagctaaac agatcgccca
     9481 ggtattgcgg gctattcgga tctaacgctt ccgtcgccag tggcagtccc atattcacca
     9541 gctcaagcag caatttacgc gcgatctgca gcccggcttc tacatcaaaa gagccatcca
     9601 tatggggatc gttaattaac cctttccagc cgacagtggt acggggtttt tcaaaataga
     9661 cgcgcattac cagatagagg ctatcgctga cctctgcggc aagggcttta aatcgacgag
     9721 catattccag agcagtttcc ggatcatgaa tggaacaagg accacatact accagaagac
     9781 gaggatcgcg cccggcgata atatctgaaa tggttttacg cgagtcagca atctgggctt
     9841 cttgttgcag gcttaatgga aaagcggcct tcagttgttc cggagtcatt aaaacctgtt
     9901 cgtcggtaat atgtacgtta ttcagcgcgt ctttttgcat gatggcgatc ctgtttatgc
     9961 tcgtttgcga tagttgatcc tcagcgagga tgacgtaacg ataacacata aagtaaagtt
    10021 ttcaatccat atttcgtaca catttcttta cgtaagcaat ttattcgcgc tttttaccct
    10081 tatttctgta tatataaatt tacaccatct ttaaaaacaa tccgctatgc tttgaaaaag
    10141 gagaaagaaa tgatgaaaaa atttatcgcc cccttgttgg ctttactggt tagcggatgt
    10201 cagattgatc cttatactca cgcgccaacc ttgaccagca ccgactggta tgatgttggt
    10261 atggaagatg cgatatcggg cagcgccatt aaagatgacg atgcatttag cgattcacag
    10321 gcggatcgcg gtctatacct taaaggatat gccgaagggc aaaagaaaac ttgccagacc
    10381 gattttactt atgcccgggg gctttctggt aaaagctttc ctgccagctg caataatgtt
    10441 gaaaatgcca gccaactgca tgaagtatgg cgaaaagggg ctgatgaaaa tgccagcaca
    10501 atacgattaa attaattacc cccaaaataa attaagcatg agattttact cattatgttt
    10561 tatttctcac attgatgacg accgcatgaa aggatgatat tttaatgagc attctgaaaa
    10621 aatatcgatg catttcgagc gaagatggtg aggatccctg aatgcgtttt tctcaccgac
    10681 tgttcttact gctgattctc ctgctgacgg gagcaccaat actcgctcag gaaccttctg
    10741 acgttgcgaa aaacgtgcgt atgatggttt ccggtattgt cagttacacc cgctggcctg
    10801 ggctatcagg gccaccaaag ttatgtatct tttcatcttc acgttttagt accgccttac
    10861 aagaaaatgc tgctacatct ttaccttatc tgcctgtcat cattcatact caacaagagg
    10921 cgataatttc aggctgcaat ggtttttatt ttggcaacga gtcaccgaca ttccagatgg
    10981 aattaaccga acaatatccg tcaaaggcgt tattattaat tgccgaacaa aataccgagt
    11041 gcattattgg tagcgccttt tgtctgatca tccacaataa tgacgtcaga tttgccgtaa
    11101 acctggatgc cttatcgcgt agcggtgtaa aggtcaaccc ggatgtctta atgctcgcac
    11161 ggaagaaaaa tgatggataa cgataattct cttcataagc gccccacgtt taaaagagca
    11221 ttacgcaaca tcagcatgac cagcatattt atcactatga cgctgatctg gctgctgctt
    11281 tccgtgacgt cagtgctaac cctgaaacaa tacgcgcaaa aaaacctggc actgacagca
    11341 gcaacaatga cttacagtct ggaagcagct gtcgtttttg ccgatggccc tgcagcaact
    11401 gaaacactgg cagcgctggg ccagcaaggc caattttcaa ctgcagaagt gcgtgataag
    11461 cagcaaaata ttctggcatc ctggcattac acccataagg aaccaggcga tactttcagc
    11521 aatttcataa gccactggct cttccctgcc cccatcattc agccgattcg tcacaatagt
    11581 gaaaccattg gcgaagtacg cttaactgct cgcgacagtt caatcagcca ttttatctgg
    11641 ttttcgctcg ctgtcctgac cggttgtatt ctgctggcat caggcatcgc aattaccctc
    11701 acccgccatt tgcacaatgg cctggtggaa gcgctgaaaa atatcaccga tgtcgtacat
    11761 gatgtgcgtt ctaaccgcaa tttttcccga cgagtttcgg aagaacgtat cgctgagttt
    11821 caccgcttcg ctctcgactt caacagtctg ctggatgaaa tggaagagtg gcagcttcgt
    11881 ttacaggcca aaaatgcgca gcttctacgt accgcgctac atgacccatt aaccgggctg
    11941 gctaaccgcg cagcgtttcg tagcggcatc aacacgttga tgaacaattc cgatgcccga
    12001 aaaacgtcgg cgttactatt tcttgatggc gataatttca aatatatcaa tgatacctgg
    12061 ggtcatgcga cgggcgatag agtcttgatt gaaatagcaa aacggttagc tgaatttggc
    12121 gggctgcgac ataaagcata ccgcctgggc ggcgatgaat tcgctatggt gctctatgat
    12181 gtacagtcgg aatctgaagt gcagcagata tgctcagcac tgacacaaat ttttaatctc
    12241 ccgtttgatc ttcataatgg ccatcaaact accatgacat taagcattgg ttacgcgatg
    12301 accattgagc acgcctctgc ggaaaattta caagagcttg ccgatcacaa tatgtatcag
    12361 gccaaacacc agcgtgccga aaaactggtg agataacaag gatatatcga tatgataaag
    12421 cacctgctag cccccctgat tttcacctcg ctaatactta ctggctgcca gtcccctcag
    12481 ggaaagttta ctcctgagca agtcgccgct atgcaatctt atggatttac tgaatccgcc
    12541 ggcgactggt cgctgggctt atcagatgcc attctgttcg caaaaaatga ctacaaattg
    12601 ctcccggaaa gccagcaaca aatccaaacc atggcagcca aattggcctc gacagggcta
    12661 acacatgccc gtatggatgg acacaccgac aactatggtg aagacagtta caacgaagtc
    12721 ttatcattaa aacgggcgaa tgtcgtggcc gatgcatggg ctatgggtgg acaaattccg
    12781 cgcagcaatc tcatcacaca gggtttagga aaaaaatatc ccatagccag taacaagacc
    12841 gcccagggcc gcgccgaaaa ccgccgcgtc gcagtggtga ttacaacccc ttaaaacacg
    12901 agcaaacaga caaaaaaagg gccagccaat tggccagccc ttcttaacag gatgtcgctt
    12961 aagcgaaatc ttagttaaga cgctctttga tacgagcagc cttaccagta cgctcacgca
    13021 ggtagtacag tttagcttta cgaacagcac cacgacgttt gacagaaatg ctgtcaacta
    13081 ccggagagtg agtctggaag acacgctcaa cgccttcgcc gttggaaatt ttacgaacag
    13141 tgaatgcaga gtgcagaccg cggttacgaa ttgcgataac cacgccctcg aatgcctgca
    13201 gacgtttttt ggaaccttca acaacccata ctttcacttc cacggtatca cccggacgga
    13261 aggaaggtac gtcctgcttc atctgctctt gttcaagttg cttaataatg ttgctcataa
    13321 tttaatctct tatcctgggt aaactgatat ctcgggggct tacgccatcc catcatgttt
    13381 atgttgctgt tgtgcgtgtt ccgttttgaa ctccgccagc aaccttgctt gctcttcagt
    13441 cagagccagg ttttccagaa gttcaggtct tctaagccag gtacggccca gcgactgttt
    13501 caaacgccag cgacgtatct cggcatggtt gcccgacagt aacactggcg gaacttccat
    13561 cccttctaac acctcaggcc gcgtatagtg cgggcaatcc agcaatcctt cagcaaagga
    13621 gtcttccgtt gccgaggcct catgtcccag tactcccgga ataaaccggg aaacggagtc
    13681 aatcagcgtc attgctggta actcaccacc actgagaacg taatcgccga ttgaccattc
    13741 ttcatcaatt tcggtttgga tcacgcgctc atctatacct tcgtagcgac cgcacaccag
    13801 aatcaatttt tgattcgttg ccagctcgct gacgcccgct tgatcaagct tgcgtccctg
    13861 tggtgacaga taaatcacct ttgcgccttc acccgccgcg gcttttgctg catgaatggc
    13921 gtcccgcaag ggttgcacca tcattaacat ccccggtccg ccgccgtaag gacgatcgtc
    13981 cacggtacgg tgccgatcat acgtgaagtc gcgaggactc cagctctgga tgctcagcag
    14041 gccattttta actgcccggc cagttacccc gtaatcggta attgcgcgga acatttcagg
    14101 aaacaggcta attatgccaa tccacatagc gccgtctttt accgtttatc cggtggttta
    14161 aaaaccagga tcccaatcta cttcgattga acgagtagtg agatcgactt tcttgataac
    14221 ctgcccatcg aggaacggta cgagacgttc cttgatacca aacgcatctt tcaggtttgc
    14281 cttaatgacg agaacgtcat tagatccggt ttccatcata tctacgactt taccgagatc
    14341 gtagccttca gtggttacta cctggcagcc catcaggtct ttccagtagt agtcaccctc
    14401 ttcaagctga ggcaactgcg atgaatccac gacaatttca caattcgtca gcaggttcgc
    14461 cgcatcacga tcgtcaacgc ctttcagctt gatgatcatg tcctgattgt ggtgcttcca
    14521 gctttccagc tggacttgct gccactgacc cgccttctgg ataaaccagg gctgatagtc
    14581 aaaaatgctt tcggcgtctt cggtggaaga aaacactctg agccacccac gaataccgta
    14641 agacgaaccc atttttccca aaacgatggg atcaacaggt gcttgcgcgg tgagttgttt
    14701 gctcatcatg accaccgtga cagattaagc tgctttgttt acttctttga tcagcgcagc
    14761 aacgcgatca gaaatagttg cgccctggcc aacccagtga gcgatgcgat ccagatccag
    14821 gcgagtgcct tcttcttttt cgctagcgat tgggttgaag aaaccaacgc gctcgatgaa
    14881 gcgaccgttg cgtgcattac ggctgtcagc gacaacaacc tggtagaacg gacgcttttt
    14941 agcgccgtga cgtgctaaac gaatagttac cataacatcc tcttgtgtga ataaaacaac
    15001 cggaccccat cgaggaacgg agtccggtgt catattaaaa gcccgaaaat tttactgatt
    15061 tctggagaaa atgcaatcag cagttaataa ctctgtcgca taaggtcatt tagcgaccag
    15121 gaaatcccgg cggcatcatc cctttcatgc ttctcatcat cttcgccatc ccgcccttct
    15181 tcattttctt catcatgcgc tgcatgtcgt cgaactgttt cagaagacgg ttaacgtcct
    15241 gcacctgcat accgcaaccg gcagcgatac ggcgcttacg cgaacctttg atgatttctg
    15301 gcttagcgcg ctctttcatc gtcatcgagt tgatgatggc ttccatacgc accagcactt
    15361 tatcgtccat ctgcgacttg acgttatccg ggatctgccc catgcccggc agcttgccca
    15421 tcaggctagc catgccgccc atatttttca tctggcgcag ctgctcaaga aagtcgttga
    15481 gatcgaagcc gtcgcctttt ttcagcttgc tggctaattt ctcagcttgc gcgcggtcaa
    15541 ctttgctttc gatatcttcg atcagtgaca gtacgtcgcc catgccgaga atacgggagg
    15601 caatacggtc cggatggaat ggctccagcg cctcggtttt ctcgccaaca ccgaggaact
    15661 tgatcggttt gccagtgatg tgacgaatag agagcgccgc accgccgcgg gcatcgccgt
    15721 ccactttggt caacactaca ccggtaagcg gtaacgcttc attgaatgct tttgccgtat
    15781 tggccgcatc ctgaccggtc atggcatcga ccacaaatag ggtttcaacc ggattaatcg
    15841 acgcatggac ttgtttgatc tcgtccatca tcgcttcgtc aacgtgcaga cgaccggcag
    15901 tatccaccag cagcacgtcg tagaatttca gtttggcttc tttcagcgcc gcgttaacga
    15961 tatctaccgg cttctgacca acatcagaag ggaagaaatc aacgcccacc tgctctgcca
    16021 gcgtctcaag ctgtttgatt gccgccgggc gatagacgtc ggcagaaacc accagtactt
    16081 tcttcttgtg cttctcgcgc aggaacttac cgagtttacc aacgctggtt gttttaccgg
    16141 caccttgcag gcccgccatc agcacgaccg caggcggttg cgcagccagg ttcagggtct
    16201 ggttctcttc gcccatcgcc gcaaccagtt cgttacggac aattttgacg aactcctgcc
    16261 ccggcgtcag gctcttatta acttcatgac caaccgcttt ctcttttacg cgattgataa
    16321 actcacgcac taccggcaga gcgacgtcag cctccagcag cgccatgcgc acttcgcgca
    16381 gcgtatcttt tacgttgtct tcagtgaggc gtccacggcc actgatattg cgcagcgtgc
    16441 gcgacaaacg atcggttaaa ttatcaaaca ttgtctctcg cctggggtgg aaacggttgg
    16501 ccgcaatcgc gacacatcat cagtattttg ccgcagtata acatgaaggc gtctttgttg
    16561 ttatgcaacg gttggagcag cgttcacctg acgctatact gcttctcttt cttattgctc
    16621 aaactgtcga cattactatg cccgtttttg ctctgctcgc gcttgtcgcc tactccgtca
    16681 gtcttgcgct gattgttccc ggtctgctgc aaaaaaacgg cggctggcgg cgcatggcta
    16741 ttatttctgc ggtcatcgcg ctggtctgcc acgcaatcgc tctggaagcc cgcatcctgc
    16801 ccgacggtga tagcggacaa aacctcagcc tgctgaacgt tggttcattg gtcagtttga
    16861 tgatctgtac ggtaatgacc attgtggctt ctcgcaatcg tggctggttg ttgctaccca
    16921 ttgtctatgc ctttgcgctt atcaacctag cgctggcgac ctttatgccc aatgaataca
    16981 tcacccatct ggaagcaacg ccggggatgc tggtgcacat tggcttatcg cttttttcct
    17041 atgccacgct aattatcgct gccctgtacg cgctgcaact ggcgtggatt gattaccaac
    17101 tgaagaacaa gaagctggcg tttaaccagg aaatgccgcc attgatgagt atcgagcgta
    17161 aaatgttcca tatcacgcag attggcgtgg tgctgctaac gctcactctt tgcactggcc
    17221 tgttctacat gcacaactta tttagcatgg aaaatatcga caaggccgtg ctctctatcg
    17281 tggcgtggtt tgtctatatt gtgctgctgt ggggacatta tcatgaagga tggcgtggac
    17341 gccgcgtcgt ctggtttaac gttgcgggtg cagtcattct gacactggcc tacttcggca
    17401 gccgaatttt tcagcagtta atcagctaaa cccagaaaag gagtttcccc tggaacacat
    17461 ttctactact acgttgatca ttattctgat catcatggtg gtcatttcag cctatttttc
    17521 cgggtccgaa accggaatga tgaccctcaa ccgctatcgt ctgcggcata tggcgaaaca
    17581 gggtaatcgc tcggccaaac gcgtcgaaaa attgctgcgt aagccagacc gcctgataag
    17641 cctggtgtta atcggcaata acctggtcaa tattcttgcc tccgcgctcg gcactattgt
    17701 tggaatgcgt ttgtacggcg atgcgggcgt ggcaattgcg actggtgtgc tgacttttgt
    17761 cgtgctggtt tttgctgagg tattgccaaa aaccattgcc gcgctgtacc cggaaaaagt
    17821 cgcttatccg agtagttttc tgctggctcc gctgcaaatt ttgatgatgc cgctggtctg
    17881 gttgctgaat gctattaccc gcatgttaat gcgcatgatg ggcatcaaaa ccgatatcgt
    17941 ggttagtggc tctttaagca aagaagaatt acgcaccatt gtgcacgaat cgcggtcaca
    18001 aatttcccgt cgcaatcagg atatgctgct gtcggtactc gatctggaaa agatgaccgt
    18061 cgatgacatc atggtgccgc gcagtgaaat tatcggtatt gatatcaacg atgactggaa
    18121 atcgattctg cgccaactct cccactcacc tcacgggcgc atcgtgctct accgtgattc
    18181 gctggacgac gccatcagta tgctgcgtgt gcgtgaagcc tggcgactca tgtcggagaa
    18241 aaaagagttc accaaagaaa ccatgctacg cgccgcggac gagatctatt ttgtcccgga
    18301 gggtacgccg ctcagcacac agttggtgaa gtttcagcgc aacaaaaaga aagtcggcct
    18361 ggtcgtcaac gagtatggag acattcaggg gctggtgacg gtcgaagata ttctcgaaga
    18421 gattgtcggc gatttcacca cgtcgatgtc gccaacactt gccgaagagg tcacgccgca
    18481 aaacgacggg tcggtgatta tcgatggcac cgccaacgtg cgagaaatta acaaagcctt
    18541 taactggcat ctaccggaag atgatgctcg tactgttaac ggcgtcattc tggaagcgct
    18601 ggaggagatt ccggtagcag gcacccgcgt gcgtataggc gagtacgata tcgatattct
    18661 cgacgtacag gacaatatga ttaagcaggt aaaagttttt cctgtaaaac cgctgcgcga
    18721 gagtgtggcg gagtaaaaaa acggcccggc attcgcatgc tggaccgtga tttattacga
    18781 aaacagaaat taagcttttg ccttcgctac agtcaccatc gccgcacgaa ttgtacgacc
    18841 gttcagcgta taacccttct gcataatgcc cagtacgtta cctggcgcaa cgtcatcaga
    18901 ttccaccatt gcgatggcct gatgcacatt cgggtccagt ggtacgttag tttcggcgat
    18961 cacttcaacg ccaaacttac gcacaacatc cagcatcgac ttcagcgtca gctcaatacc
    19021 ttcaaccatc gcggacatat ccgggttagc tttatcagcc acttccagcg cacgatccag
    19081 gctatcaatc accggcagca attcgttgat gaatttctcc agcgcgaatt tgtgagcttt
    19141 ttcaatatcc agttcagtac gacgacgcag gttttccatt tcggctttta cgcgcaaaat
    19201 gccgtcacgt tcacgggtct gggcttcagc cagctgagct tcgagattcg caattttttc
    19261 atcgcgcgga tccacctgct cagcagaagc ttctggctca actgcctcaa tctcttcgtg
    19321 ctgatccatg ataatttctt ccggggcttg cccctcaggc gttttctgtt ctttactact
    19381 catgaatttc tccgcgtttt tttcgcattc atctcgctaa cttcgcttat tatggggatc
    19441 agtttcaggg tttcaaggga agcactcaca ttgtcatcaa tcttcgcaac aaggacctcg
    19501 gaaaaatgaa taatcatttc aagtgtattg gcattgtggg acacccacgg caccccactg
    19561 cactgacaac acatgaaatg ctctaccgct ggctgtgcac aaaaggttac gaggtcatcg
    19621 ttgagcaaca aatcgctcac gaactgcaac tgaagaatgt gaaaactggc acgctcgcgg
    19681 agattgggca acaggctgat ctcgcggttg tcgttggcgg cgacggtaat atgctgggcg
    19741 cggcgcgcac gctcgcccgc tacgatatta aagttattgg aatcaaccgt ggcaacctgg
    19801 gtttcctgac tgaccttgat cccgataacg cccagcaaca attagccgat gtgctggaag
    19861 gccactacat cagcgagaaa cgttttttgc tggaagcgca agtctgtcag caagattgcc
    19921 agaaacgcat cagcacggcg attaacgaag tggtacttca tcctggcaaa gtagcgcata
    19981 tgattgagtt cgaagtgtat atcgacgaga tctttgcgtt ttcgcagcgt tccgatggac
    20041 tgattatttc gacgccaaca ggctccaccg catattccct ctctgcgggc ggtcctattc
    20101 tgacaccctc tctggatgcg attaccctgg tgcccatgtt cccgcatacg ttgtcagcac
    20161 gaccactggt cataaacagc agcagcacga tccgtctgcg tttttcgcat cgccgtaacg
    20221 acctggaaat cagttgcgac agccagatag cacttccgat tcaggaaggt gaagatgtcc
    20281 tgattcgtcg ctgtgattac catctgaatc tgattcatcc gaaagattac agttatttca
    20341 atacattaag caccaagctc ggctggtcaa aaaaattatt ctaattttac gccagcctct
    20401 ttactgtata taaaaccagt ttatactgta cacaataaca gtaatggttt ttcatacagg
    20461 aaaacaacta tgttggcaca actgaccatc agcaactttg ctatcgttcg tgagcttgag
    20521 attgattttc atagcggcat gaccgtaata actggcgaga ccggcgcggg taaatctatt
    20581 gcaatagatg ccctcggcct ttgtctcggt ggtcgcgctg aagccgacat ggtgcgtacc
    20641 ggcgctgctc gtgccgacct gtgcgcccgt ttttctctga aagatacgcc agcggccctg
    20701 cgttggctgg aagaaaacca gcttgaagac gggcatgaat gtttgcttcg tcgcgtaatc
    20761 agcagcgatg gtcgctcccg tggtttcatc aacggtacag ctgttcctct gtcacaactg
    20821 cgcgaactgg gtcagttgct gattcagatc catggtcagc acgctcatca gttactcacc
    20881 aaacccgagc accaaaaatt cctgcttgat ggctatgcca atgaaacctc tcagctccag
    20941 gaaatgaccg cacgttatca gttgtggcat caaagctgcc gtgacctcgc gcatcatcag
    21001 cagttaagtc aggaacgcgc cgcccgtgcg gagctgctgc aataccaatt aaaagaactt
    21061 aacgaattta atccgcagcc tggagagttt gagcaaatcg acgaagagta caaacgtctg
    21121 gcgaacagcg gtcaattgct gaccaccagc cagaatgcat tggcattaat ggctgacggt
    21181 gaagacgcaa atctgcaaag tcaactttac acggctaaac aactggtgag cgaattgatt
    21241 ggcatggaca gcaaactgtc cggcgtactt gatatgctgg aagaggctac catccagatt
    21301 gctgaagcca gtgatgaact acgccactac tgcgatcgtc tggatctcga tcccaaccga
    21361 ctgtttgaac ttgaacagcg catctcaaaa cagatttcgc tggcacgtaa acatcacgtc
    21421 agccctgagg cattgccaca gtattaccag tcgctactgg aagaacagca gcaactggac
    21481 gatcaggccg actcacaaga aacgctcgcg ctggcggtaa cgaaacatca tcagcaggca
    21541 ctggaaacgg cgcgcgcgtt acaccagcaa cgccagcatt atgcaaatga gttggcacag
    21601 ctgatcaccg atagtatgca tgcactctct atgccacatg ggcagtttac gatcgatgtt
    21661 aaatttgacg agcatcacct gggcgctgac ggcgctgatc gtattgagtt tcgggtaacc
    21721 accaacccag gtcagccaat gcagcctatt gccaaagtcg catccggtgg tgagttgtcc
    21781 cgcatcgcat tggcaatcca ggtcattacc gcgcgtaaaa tggaaacccc agcactgatt
    21841 tttgatgaag tggatgtagg gattagcggc ccaacagcgg cagttgtcgg caaactgcta
    21901 cgtcaacttg gcgaatcaac tcaggtgatg tgtgttaccc acctgccaca agtcgcggga
    21961 tatggtcatc aacactattt tgtcagcaaa gaaaccgatg gtgcgatgac agaaacgcat
    22021 atgcaatccc tggataaaaa agcgcggtta caagagttgg cgcgcctgct tggtggcagt
    22081 gaagtcacac gtaacacact ggcgaatgcg aaagaactgc ttgcggcgta aacttttttc
    22141 ctgcttcacg gtcagagtaa acagcaaaac gccgtaagac cggaaagcaa aaggttttaa
    22201 agtgatgaaa ggtctattat catcggcata ttacagatga gccacgtact gctcgggccc
    22261 gaaaaggaat caaatcacta tgcgctgtaa aacgctgact gctgcagcag cagtactatt
    22321 gatgttgacc gcaggctgtt ccactctgga gcgagtggtt taccgtcctg acatcaacca
    22381 ggggaactat ctgaccgcta acgacgtatc caaaatacgt gttggcatga cgcaacaaca
    22441 agttgcgtac gcattgggta caccgctgat gtccgatcca tttggtacaa atacctggtt
    22501 ctatgtcttc cgccagcaac ctggtcatga aggtgtaacg cagcaaacgc tgacgctgac
    22561 ctttaacagt agcggtgtgt tgaccaacat tgataacaaa cctgcgctga gtggtaacta
    22621 ataataaagt tgctctcaaa gacgttaaaa aaggtgctca atgagcacct tttttctgtc
    22681 tgttatttat tcgctgattt ttctgctcgt tgcctgcgaa gctctttcgg atcggcaatg
    22741 agaggacgat aaatctccac ccgatcgcca tcatgcacaa tatcgctgag ttttgccgga
    22801 cggctgtaaa tgccgacttt gtttttagtt aaatcgatat cggtacgcaa ttccagcaaa
    22861 ccactggcgc gaatagcttc ttcaaccgtc gcgccctcct gcaacgtcac gcgctgcagg
    22921 tactgcttct caggtagcgc ataagccacc tcaacggcaa ttttacctgg cactgtagac
    22981 ctcttttgca cgaacagtaa aagcctgcac catattagct gccagctctt taaacacacg
    23041 accaaaggcg agttcaatca acttattggt aaactcaaag tcgagatgaa actcaatacg
    23101 gcacgcgtcc tggctcaacg gcgtaaactt ccaaccgcct atcaatttct taaacggtcc
    23161 atcaaccaga ctcatgagaa tactttgatt actggtcaac tggttgcggg ttgtaaacgt
    23221 tttgctgatc ccagccttag acacatctac cgcagcggtc atctgcccag gagtggactc
    23281 cagaatccgg cttccagtgc accctggtaa aaactgagga taagactgaa cgtcattcac
    23341 taactgatac atttgctccg cgctgtaggg taccagtgcg gtccggctaa tctgaggcat
    23401 aacaatttcc atcaacaaaa atccaacaaa taatatcatt tatcctgctg taaaaaaaac
    23461 gctatcccgg cgctgggtaa catcgggatc atgctaagat agagccttgt cccccgcagg
    23521 attgatatgg ggtgttttcg atttcagatt accgatgatt cacgacgctt atgacgaaga
    23581 aaaaagcaca taaacctggt tcagcgacca tcgcgcttaa caagcgcgcc cgtcacgaat
    23641 actttatcga agaagagttc gaagcgggac ttgccctgca aggctgggag gttaaatccc
    23701 tgcgtgcagg aaaagccaat atcagcgaca gctacgtcct tctgcgtgac ggagaggcat
    23761 ttctgtttgg cgctaacatc acgccaatgg ctgtggcctc cacgcatgtg gtgtgcgatc
    23821 ctacccgtac ccgcaagtta cttctcaacc agcgcgaact ggactcattg tacggtcgcg
    23881 taaatcgaga aggctatacc gtagtggcgc tctccctgta ctggaaaaat gcctggtgca
    23941 aagtgaaaat cggcgtcgcc aaaggtaaaa aacagcacga taaacgttca gatatcaaag
    24001 aacgcgaatg gcaggtggat aaagcgcgta tcatgaaaaa cgcccatcgt taaacctata
    24061 taagcgatac taatcaaatc ctcaccgcgc ctccctatcc ggtggcgcga atgaacatct
    24121 tgtcgactgt caaatctgac acagatgtag ccatcccatt gcttaatcga aaaaaaatca
    24181 tactatgcag gcgctaattc caggatgata acgccttttg ggctagtcat gctgctcata
    24241 aatctggtat acttaccgtt acacattggg gctgattctg gattcgacgg gatttgcgaa
    24301 acccaaggtg catgccgagg ggcggttggc ctcgtaaaaa gccgcaaaaa atagtcgcaa
    24361 acgacgaaaa ctacgcttta gcagcttaat aacctgctta gagccctctc tccctagcct
    24421 ccgctcttag gacggggatc aagagaggtc aaacccaaaa gagatcgcgt ggaagccctg
    24481 cctggggttg aagcgttaaa acttaatcag gctagtttgt tagtggcgtg tccgtccgca
    24541 gctggcaagc gaatgtaaag actgactaag catgtagtac cgaggatgta ggaatttcgg
    24601 acgcgggttc aactcccgcc agctccacca atcatgattg gacggtgtaa ggacaacacc
    24661 aacaaaaaca ggaagttagc agtctcagca ggacaccgac cagacggtga ggagacaaaa
    24721 aaggatacgc aaaggagccg cggctctcga gtgacacaaa agcccgctta tgcgggcttt
    24781 ttgtttttcc cttaagttcc tagccgctta tctataacta tggaaaaatg ttaaccctga
    24841 ctgtatgtta acaaagggat gtatatgtcg gtttttcata actggctgct tgatatcgca
    24901 agcgggaatt actttatcta catcaaacgc ctttctgcaa acgacacagg cgcaacaggt
    24961 ggccatcagg tcggacttta tatcccctca aatatcgttg aaaagctttt tccatctatc
    25021 aatcatactc gcgaactgaa cccttcagtc ttccttactg cgcatgtatc atcccatgat
    25081 tgccctgata cccaagcacg cgcaatttat tacaacaacc gttattttgg taagacccga
    25141 aacgaaaaaa gaattacgcg ctgggggaga ggaagtccat tacagaaccc tgaaaataca
    25201 ggagccctca caattcttgc tttcaggtta aacgaacaga acactgactg ttccgaggta
    25261 gatatatggg tctgcgtcaa tcccgatgaa gaggatatca tcgagtctgc tattggcgaa
    25321 atcatacctg gaaccctaat ttccggccct gccggacaaa ttttgggcgg attgtctctt
    25381 cagcaaactc cagtaaatca taaatatgtt attcctgaag actggaagaa gcgttttcct
    25441 tctggaaacg aaattattca atatgctgct ggccattatg ctaaaaactc caaggatcca
    25501 gatgagcaac tgattgaccg tcggcgtgtc gagtatgata tttttctact cgtcgaggaa
    25561 ttacatgttc ttgatattat taagaaagga ttcgattctg tagatgagtt tattgcatta
    25621 gccaactctg tcagtaatcg acgtaaatca agggcaggca aatcacttga acttcaccta
    25681 gagaagcttt ttatcgagca cggactacgg catttctcca ctcaggcagt tactgaaggt
    25741 aataaaaaac cagatttcct gtttccttca gcagaggcat atcataacgt tgaatttcct
    25801 gtagaaaact tacgtatgct ggcagtaaag accacctgca aagatcgctg gcgtcagata
    25861 ctgaatgaag cagataaaat ccatcaggta catttattta cactgcaaga aggtgtttct
    25921 tcagcacaat accgagaaat gaaagatgcg ggtgtcagac tcgttgtacc atcaacttta
    25981 cataaaaaat acccagaagc agttagagaa gaattaataa cgctcggagc attcattact
    26041 gagctgatag agctttacgc tgaactatca taggctgact cccggcttaa aaggccggga
    26101 gatgttctca aggctgccca gtcttaccag catcagcaga aacagctttg aggatatagg
    26161 gttccagaag tctggcaaca gcttcaaata ctggcaccac aactgagtta ccgaactgcc
    26221 gatatgactg agtatctgaa accggaatac ggaatggttt ccctccaggt ttttcaaatc
    26281 ccataaggcg tgcgcactct cggggagtca gcctgcgtgg tcgacgagcc tgattactct
    26341 cattcataaa gtcagcctct cccgttgcca tatcccaacc acgatcaata agaatttctg
    26401 atccgtcttt gtgatatctg gcagaaagtg tgcgtgcaat gctttcctta ttctcaggat
    26461 tgaccaaccc aaagccaaaa ccattcccct tggctgcatg ctttttggcg tagttataaa
    26521 ggtactccca tagttttggc gtaagtatat atttactgtc gactacaggc tccagcaatt
    26581 caccaaatga tgggcggtgt tccggataaa aacgactgat atcacgcaag gtaaacccct
    26641 tgtgaatatt cagatctcgt ctaaatccga ccagaacaat gcgttcacga tgctgaggca
    26701 aaaaatgctt cccatcgata atctttggat cgttttttcc catttctgca gcatcggcaa
    26761 cttcgtagcc cagctcgtca agggtctcca taatgacttt gaaagtttta cccttatcat
    26821 ggctcttcag atttttgaca ttttccagca caaaaattgc cggttttttt gctcgtataa
    26881 tacgtgccac gtcaaaaaaa agtgttcctt gtgcttcaca ttcaaaacca tgcgcacgac
    26941 caagtgagtt tttcttacta acaccagcaa ggctaaatgg ctggcacggg aaccccgcaa
    27001 gaagcacatc atgatccggc acatgctcat caatatatgc ataagcatcc gtttccaata
    27061 catcggtttt atcactcagc gtgacttccc gaatatcgag attgaattta tgcacctgtt
    27121 catcgttaaa ccagttggcc ttgtatgtac gcacagcatc tttattccat tcactggtaa
    27181 aaacacactg gcctccaatg gcctcaaaac ctttccgtat ccctccaatt ccagcaaata
    27241 agtcaatgaa gcggaaagca tattccggat ggtttgcagg tggttctggt agcatcttac
    27301 gcagaagaga ctcttctact gaagtcaacg attttggtaa acacttgcca ttaatccagc
    27361 ggttaatggt ttcacggctc cactcatttt ttccgacttt tctcagtaat tcagccacat
    27421 acttctgatc atagatttcc agcactttct cgataagctt tttatcattt tcctgtcgca
    27481 gcttttcttc cgcctcggct tccttcagca gatgctgtgc caacacttca aattcagaca
    27541 taattcctcc aaggggtcta atgggtgaaa ctttatcact cattcaaccc agaaggaaat
    27601 gttttatctg gatatttaaa cagtgactac aacgtaatct agcactggtg atgctttgtt
    27661 aggcatagag aatcattcta tatacgacta atgacagaaa aacagcagac aagtagtttg
    27721 ttcataaatt aacgcatact atgtgtctac ggttttcgag accggtccaa tcatcaaacg
    27781 aaacataaaa ttagctcaca ttatgaggaa aagtatcttt tttgtactat gtaaattcaa
    27841 aggcttagcc tcatttctcc gatggttttc tcaacactac tggttgtgag cccttgcaat
    27901 gatcattaat atacgtctca caaataattc ttcatagata ttgcaaaatg gatattactg
    27961 agtttccttc tggagtaatt gaacaccttg gctggtatgt ataccgattg attgatccga
    28021 gggacggaag caccttctat gtagggaaag gcaaaggtaa ccgcgtattt gcccatatgc
    28081 gcggtgaagt ggcagcgact gatgatgacg agttactgag caacaagcta aagcaaatta
    28141 gagaaataag gttagcagga cttgaagtta tccatgtcat ccatcgacac ggaatgactg
    28201 atgaaaagac ggcgtacgaa gttgaagcag cacttattga tgcctaccct gggttaacga
    28261 atatcatgaa tggtgctggc agcaatgaat tcggcgccgc gcatgtcaaa gagttgatag
    28321 caacatatca gcccgaaacc ataacatttc atcataaagc attaatgata tccgttaaca
    28381 gaagtgcaaa ggattcagag ctttatgatg cggttcgatt tagctggcgc attaatgtct
    28441 ctcgcgccag ccaagcagaa atcattcttg ctactgtaag ggggatcgtt cgaggggttt
    28501 tcattgctga taaatggctc aaatcaacac gtgaaaattt cccttcgttg aaatactggg
    28561 acgaggatcc tgactttgag gcaacacaaa gttcgcgcta tggttttgaa ggtcgagaag
    28621 ccccacctga aatagcaaat ctttatcttg gaaaaaaaat accagatgaa ttaagaaaaa
    28681 aaggagctat gtccccggtc cgttactcac ctaatttttg agtctttaag tgataagcat
    28741 aaaccgcagc acgtcatgca tacgtcgtgt ctgcggtttt tcttttttgc ttacacggtg
    28801 tctggttctt ctggccactc aatatccggt gcagttgatg tatcaacacg gttcagcaac
    28861 acccgatact tcttccaggc ttccagcaac gagttttctt cctccgttgc gatttccaga
    28921 tctacagcat cctgaagtgg cgcaatatgc tcactggcta cctgcatcag gctgtttttt
    28981 gtttcttctg cctcccggat ccggaacagt ttttctgctt ccgtatcctt cccccaggct
    29041 gtgccgttcc acttctgata ctcccctccc ggcgacaacc aggtaacatt ttccggtaac
    29101 ggaccgagtt cagaaataaa taacgcgtcg ccggaagcca cgtcataaac cgttttaccc
    29161 cgatggtctt caacgagatg ccacgatgcc tcatcactgt tgaaaacagc cacaaagcca
    29221 gcaggaatat ctggtggtgc aatatcggta ctgtttgctg gcagacctgt atgaggcgga
    29281 atatatgcat caccttcacc aataaattca ttagttccgg ccagcagatt ataaattgtt
    29341 atggtccgtg gttgttcact cattctgaat gccattatgc aagcctcaca atatagttaa
    29401 atgcgatgtt tttgacggtg ttttccgcgt taccagcagc gttaacggtg atggtgtgtc
    29461 catgtgaacc aatcgcaacg gagtgcgtat gagcaccaat accgacagta tgcgcgtgtg
    29521 cacctgcaga tgctgctgtg ccggacagtg aatggctatg attaccatct gtactggtat
    29581 tcgctaacca ccccgtagac atacctactg agccttgtac accccaggta ttttgacctg
    29641 agcttgtata accatattga taagtatctt taaaaacact ggggttaaat cgacggccat
    29701 ctctatggct gtgattacca gctgcattcg tgctgccact taaactatgg gtatgcgcac
    29761 cagtgttatt cgtggattta gtgccgtaat caaacgacga tgtggttttc gtccccaaat
    29821 ccgtactgga tgcgctggcg ctgtgggtgt gcgatttaat gccatcctgt tcctgagaca
    29881 atacggcacg accactggcg ggcttgccct taatcgtcca gccacgcata tcagggatca
    29941 cgcctgacgg ataagcggct gcaagtttcg ggtaagcaga tttgtcaaaa gtctgcccct
    30001 gcatcagggc ataaccagac ggaacggtat ctgatggcca cgggattggt gcaccgactg
    30061 gataaaactc tgcaggagga tgagccgagg tgtaaagctg cgcccacggc gaccagtttg
    30121 cgtcggtcgt atcccgtcgt gaacgaataa atgccggagc atgagcaccg cttgtaccac
    30181 tccagccgat gagtaactca ccttcgccaa cggctgtcat ccctttcagg tgaatgatat
    30241 ttccatacgc tgttggatat ccgttgttat acacctcgta taactcaaga cctgttgccc
    30301 cctgcgtatt gtctgtcagc gcggttaccc gaccttttga agacagatta actgatgata
    30361 ctgctgttcc acctgacggt aacgccccga tctctgatgc cgttggctta tttctggagt
    30421 tatagtccct tcgccagcca ggtgaataat ctgttccgtg attaatatag gtaaactggg
    30481 cgttagttgt tccaccacca gtggaggtgg tcggtgtggt aatgcggatc gtcatcgctg
    30541 actttatccc cattatttca atgacagctc cggcgagatg aatattaccg cagccagtat
    30601 cagtaatgat tttattattg ccataagacc aggaaccctt gcacatccag tagggatggt
    30661 taaatgctcc ctgagaatcc agccactcga taaactgtgc agtcgtccag tttcctgttg
    30721 ttgtgcttac tgacccaccg aaggcacggc aggcaccaat atttttcgta aaggtgtctt
    30781 tgccagggat atccgcaccg ttctgatctt tctgcagacg tttctcagca ttgtcattgg
    30841 ctgcttttac tgcctttggc gttgccgcca gcgtttcaga cgtgctgttg gtcgcgctgc
    30901 ttagctggat tatccctttc tgtgctgtcg ttgcatcctg tgcggtgtat ttcccgttag
    30961 ccaggtcata cgcggcctta acggcttttg gcgttgccgc cagtgactcg gaagtgctgt
    31021 tggtcgcact gctgagctgt actatcccct ttttcgtcgt gctcgcatcc tcaagcgcca
    31081 cggcggatgc aatatcctct gcccgttttg ccgctgtctc agcgcgcgtt gctgcagatt
    31141 ccgccgtact tttgctctga gctgcagccg tcgcactacc agcagcctct gtcgccttcg
    31201 tggatgccgt cgtggcgcta cccttcgctg ctgacgcctg tctggtcgcc tcatcttttg
    31261 aagcagacgc agatgatgcc gatgacgacg ccgaactggc tgacgatgcg gcagccgttt
    31321 ttgaggattc tgcgctggtt tccgacgctt tcgcgttcgt ttcggatgtc ttcgctgcgg
    31381 aagcagacct cgctgctgcg ctggcctgtt cagtggcttc gccagccttc gttgtggctg
    31441 ttgaagcaga cgatgcggcg ctttctgccg attttccggc ggcggtggca ctggctgagg
    31501 cctgcccggc acttgttgac gctgcactgg cagacgacgc agccgctgtt tttgagcctg
    31561 ccgcagccga ggcgctctgt cccgctgccg tttcagaaga cctggcgttc gtctctgacg
    31621 tttttgccgc cttcgcggaa tttcctgccg ctgttgccga ggaagctgcg ctactggcgc
    31681 tcgaggatgc gttcgtttct gatgattttg ccgcctcttt tgaagccgcc gcatcccggg
    31741 ctgaagtggc agcttctgac gctttcgtgg tcgcggtgga tgcagaagtg gctgctgatt
    31801 gttgtgacgc tgcagcattc gtttctgacg ttttcgcggc actggcactg gtagctgccg
    31861 cgctttttga ggactctgca gcggcagcac tttttgatgc ttcagtggcc tttgttgatg
    31921 ccgttcctgc gctggaagtc gctgactgag ccgacgacgc ggcctgtccg gctgacgtgc
    31981 tggctgcgcg tgctgagcct gcagcatcag tcgcatgggt tgccgcctca cgggctgatg
    32041 tgctggcatc actggctgac ttcttcgcgg ctgccgtgtt ctgtgccacc acggacgcgt
    32101 tacgcgccac ctcttccacc atcagctcaa aacggcgcag tgcctccgga cgggcatcat
    32161 cctccgtcat ggcaccgaga aaatcattca gcgtaccggg tcgggaatct tcatacactg
    32221 tgatggtccc ggcatgtgac ggcgggaatc cttccaccaa cagaataacg ctgtactgac
    32281 cgtactcaac gtccatactg taacgcccgg cttcatccgg attttcagat gccagcgtgt
    32341 tcaccaccac cgtggtactg ttacgttttg ctttcagctg gattgtgcag ttctgtaccg
    32401 gttttcctgt gccgtctttc agtacacctg aaatttttac tgccatattc accccacaaa
    32461 aaagcccgcc tgaaccggcg ggctgtcata acactgtgtt acctggctaa tcagaattta
    32521 taaccaacac ccacgatgaa cccgtcagtg cgccagtcac cgctgccgga gccttcataa
    32581 gcgacatcaa cggccacgga ttcggtcggg ttaaactgca cgccagcccc ccacgccaga
    32641 gacgtgttgc tgtggcgacc gtcatcactt ccggtcagca catcgtgcgt tttccccgta
    32701 ttgtcggtca cctgcagata atccccggag aaagtcgaca cacggctgta agccacaccc
    32761 gccatcgcat acgcgctgaa ccattcattc acgcgcacag acggccccgc cattacgctg
    32821 aaccagcggt tacgaacgga atcttcatgc cagcgggtat cgctgtaacg ggtcagctgg
    32881 cgattcttgt ctcctgcata gctgaatgac gtcaccagcc ccagtgtgtc cgtaaactca
    32941 taacggtatt tcacgttaat cccgttcaga tcatcactgc cggggacgtt catcgaggca
    33001 tgaagatacc ccgcgctcag cgtggactga tgttcagacg cccatgcagg cgcaccggat
    33061 acggccagac aaatggctgc ggacaaaatg gctgcacaaa ctttacgcat aattacctct
    33121 cgcttttctg caataaaaaa ggcgtcattc ctgacgccct ttattggggt tataaatatt
    33181 tcaacgaata ctgatgccgg aagcggcttt tttggtcaca atcaccgtac agtcggtgat
    33241 attgcctgcc ccctgattgc ctttctggaa aatcttaaac tccagagtga cgcttcccct
    33301 gccactcggc atatcaataa ccgcactgta actaccggga atggcccctt tagtttctct
    33361 ggatgcgatt aatacgccgt ttttgcgaac ttcaaaacca taacccgtgt atcgcgtgcc
    33421 tcctgggtta tttccgctcc ccggatcgtc atacgctata ccgttaaaaa taatgggcgg
    33481 aataataatc tggcggtcaa agttatgatc atcgctgatg gtgactgtaa ccgtaccgtt
    33541 tggtgtttcc gtgttacccc acgtaccgac ttttttcggg aaggcttttg atacagcttt
    33601 aacgaaatct cctctgacct gggtcgcctc cagcatgccc ttaatcgtac agttctggtt
    33661 aatcgtgaca ttgttgagcg ttcctgagtt cgcattcaca ctgccactga tatccgcatt
    33721 tttcgccgtc agtctcccgt ctgatgtcag ggaaaatgcc ggaggattac cgccgctggt
    33781 aatggtgggg gccgtcaggc gtttcaggaa cacttcattc atgaatatct gatcgccctg
    33841 accaacaaac atcggctttg tgttgccatt cgcaggatta atcatcgcaa tcctgtctgc
    33901 tgccagcagc acctgactct gcatgccgtc aggggtgttc tcaataccgg caccgatacc
    33961 cgcaatataa aggcgtccgt cctgcatctg ctgcagcttc actgcccaca tgctgttcag
    34021 gttattattt gtatcaacct gaaccttctg tatctgctgg atcgctgcac tctggtcttc
    34081 cagtttctta ttgacggtct gtgttatttc attgctgaca tccgttatgg acgtcctgat
    34141 ttcagtcagg tcaggcgcaa gctgaccgtt atcaatctgc gtccacagct cctgagccag
    34201 atgggttttc cctatctcgc ctttgaaaaa atccagatag cctgatgcat catcactcgg
    34261 ctgaccgaca gcctccacga atgccgattt gccaacggtg ttcacactgc gaacgtaaaa
    34321 ataataatca tggcccggtt tgatattgat actggcggct atccagtaca gtgccgtacc
    34381 aagataacgc gcgctggttt caacctgcct gatatccgca atccgttttt ccgagaacca
    34441 gaactcaaac tgtaccgtcg ggtcataaac cgcaagatgc ggcgtggcgg ttatctgaaa
    34501 atagcccggc gtcagctcaa tccgcgacgg cgctgccggt gcggcaatcc ggaacgatac
    34561 cgacgccgga tcgccctgct gcccccacgc atttactgcc cggactgtca gcctgtagtt
    34621 ccccagcgcc agttgtgtga agcggtatgt ggtttccgtc gtccgggccg tgctgaccag
    34681 ccgctcacgg ccgtcatccg ctgccacggt caggcgaagc aggaagctca cgcccttcac
    34741 caccttcggc gtgtcccagc gggccagcac ctggtattcc ccgctgtctg cggtgacttc
    34801 tgcggtcagg tgctgcaccg ctggcggcgt gacaccattt accgtgcagc tctggtcgcc
    34861 gtcaaagtgc gccccgttat ccacgatggc ctctttttcc ggtacatgct gcacggcggt
    34921 gatggcatac gtgccgtcgt cgttctcacg gatactcacg cagcggaaca ggcgctggcg
    34981 caacgtcggc agcttcagcc cccatacgct gtattcagca acgccgtcag gaacacggct
    35041 cactttcacc ttcacgccgt cggtgacgga ctgaacctcc acgctgaccg gactcccctg
    35101 cccgtcaacc aggcttatca gcgtggtgcc ggaagatggc agcgtgattt cacggtcgag
    35161 cgtcagcgtc cgggtctggc tgtttaccgc cagcacgcgc ccgccggtgc ggataccggc
    35221 atagtcatca tcgcagattt caatgacatc gcccggtaca tggcgaagcc cttcggcacc
    35281 cacgctgaag tccacggtct gcgtttccag cagttctgtt ttaatcagcc acagcccggc
    35341 gcggtgtgcc tgcccccggc tggtacagcc aaaagcatcc atcttcgtga cgttacgacc
    35401 gtaacgggca atggcctgcg tgtcctccac aagctctgtc gccgtctccc agccgttatt
    35461 cgggtcaatc cagttcacct caacggcatt atggcggtcc ttcagggcgc tgaagctgta
    35521 gcggaacggc gcaccatcat ccggcatcac cacattactg cggttatagg tccacacctt
    35581 atccgacggt cggtcctgca cgaacgtcag cgtctgcccg ttccataccg gcatacagcg
    35641 catcgcagag cagaaatcac tgagcacatc ccacgccttg cgctgtgtgg tcagccaggc
    35701 attacaggtg atgcgcggct ccgtgccgcc aaaaccgtcc ggcaccgact gatcgcaatg
    35761 ctggccgatg acatacagcg cccatttgtc cacatccgcc gcaccaagac gtttccccat
    35821 gccgtagcgc ggatgggtca gcatatccca cagacaccag gccatgttgt tgctgtatgc
    35881 tggcttaaac gttccgtccc agataccgct gtattgccgc gtctgcgggt tatagttcga
    35941 cggcacctgc agaatgcgcc cgcgcagatg ataattacgg ctcacctgct ggctgccgaa
    36001 ctgctccgaa tccacctgca cgccgaccag tgccgtgttc gggtagcact gtttcacatc
    36061 gatgatttcg gtgtatgacg accagagcgt tttgttctgc agctggtctg tggtgctgtc
    36121 ccgcgtcatc ctgcgcatcc gtatattgaa cgggcgcggc ggcaggttac ccaccaccac
    36181 cgaggccaga tactgcgagg tggttttgcc cttaatggtg atgtcttttt ccgtcaccca
    36241 gccaccatta cgctggatct gaaccagcag gcggacttcc gacggattcc ggtccccctt
    36301 tgaggtggtt tccaccagtg cctgcacgcc gaaggtaaag cgcagacggt cgatgtttgc
    36361 agacgtaatg gtgcgggtga tcggcgtgtc atatttcact tccgtaccca gcaccgtctc
    36421 ggagccggag gattcaaacc cctccggcgg tgtctgctcc tgctcacctg cccggaacac
    36481 caccgtgaca ccggagatgt tggtattccc ctcagtgtcc agcaccggcg tactgttcag
    36541 cagcacgctt tttaatccat ccaccggacc ttcaaccggc ccttcgctga tggcatcgat
    36601 cacactcagc agctgcgtgg acttcaggtt gtccttcgct tcgcgcgggg tatgcccctt
    36661 actgctgcct ttacccattc ctcacgctcc ataaatgaca aaaccgcccg caggcggttt
    36721 cacataaaac attttgcatc agcgaccaat caccacaacc tgaccaccgt ccccttcgtc
    36781 tgccgtgctg atctcctgag aaaccacgcg agaccccacg cgcatttcac cgtacagaac
    36841 aggcagaaca ttgccctggg caaccatgtt atccagtgag gagaaatagg tgttctgttt
    36901 gccgttatct gtactggctg ccgtgggcgt cctggctttc ggtgccagca tctgcgccac
    36961 tccgcccagg atcatactgg cccctgccgc atacatgccc gatacagccg cggcccccag
    37021 ccagcccaca gggttccacc atgccaccgc aatcagcgcc gccccaagca ccacctgaaa
    37081 cacaccgcca cttttagctc ccgccagacg cggcacgatg tggatcacgg caccatttgc
    37141 cagcggctca ttaagacggg cagataattc attttcgcct gcatcacgcc cggcaatccg
    37201 tacctgatac cagccgtcgc tcagtttctg acgaaacgcc gggagctgtg tggccagtgc
    37261 ccggatggct tcagcccccg ttttcacacg aaggtcgata cggcgaccaa atcgttgcaa
    37321 atccccgtaa aggcagatgc gtgccatgcc cggtgacgcc agagggagtg tgtgcgtcgc
    37381 tgccatttgt cggtgtacct ctctcgttta ctcagttgtt caggaatatg gtgcagcagc
    37441 tcgccgtcgc cacagtaaat ggcggcatga ttcggcaccg atgaaccaaa acagcacagc
    37501 agcacgtcgc caggctgcgc ctctgtcagt gggacacggt aaaaacccgt tgcctccata
    37561 ttgtcaagat agagattctg gccgtgacgc caccagtcat ccccgcgatg caaatccggc
    37621 atctcaattc ccgccagatg gtaagcgtcc cggaacagcg tgtaacagtc cgtcaccccg
    37681 tgctcaaagc gccgcccggt gagatgcggc acacagcgga atttatgaat cgccccccgg
    37741 cagaccagcc accacggcaa atcactctgc acctgcagcc gccggtcggc ctcactcagc
    37801 cagggcagac caccggggtg gctgtggacc agcgccacaa tctctccctg catttctgca
    37861 ctcagccagt cctccggcga catccggaaa taatcctccg gctcaccgga gatattcacg
    37921 cagggaaaat atctttcccc ctccggcgtt ctcaccacga agccgcacga ctccgctggc
    37981 gcacatcgcc gggcgtgcgc cagaatcgct gattctgtct ctgtcatggg attactgcga
    38041 aagtttgtta atggaaagga agccgccaaa gttgccgacg ttattgcgaa acttacagcc
    38101 gctcaggcat ttgctgcatt tatccttcgt gatatcggac gtcggctggt catattcatc
    38161 cgcgactgcc ggaccgtgat aaccgcactc atcaccgcga taggtccagg tgcaggtgtt
    38221 ggccagcatg atacgtcccg gaaaaacagc gccatccgtt tccgtcggcg tggacagtac
    38281 aaaagaggca ctcaccgcgc tcagttcgct gcactgctcg atgcgccagc ggctgatcac
    38341 ctcctgctcc ggatcggcgt cactgtttcc gttgacgaag ttcaccgcat ccagaaaacg
    38401 ggcgtaaacc ttacgccgga ccaccgttcc gccgaccaga ctctgcaggt cttccgccat
    38461 cccggtgacc atgccgtgca ggttagaaac cgtcagtgtc ggacgggcag cactgccctt
    38521 gccattcagt tcaaatcccg tcccctgaat ggggtatgcc tgatactgcc gcccctgcca
    38581 ggtaaccggc tcaccttttt cgttctgctc attacagaaa aaataacgtt caccaccgac
    38641 ctctgtcaga tcgatttccc agagcaccac ctgggctgac tgagtgaggc gtgtcgtctc
    38701 atgatgtgtt tcctgtggaa tatcctgcat cagagcctcc tatgccacga cctgttcaaa
    38761 atctgccgtt atggttatcc acagcgcccc cacgcttgcc gaccatttac gacaaaccac
    38821 cctgatcggc ttccagtcat aaggtggcgt ccactgaaat gcgcggacgc caccgtgccg
    38881 ttccagaaag gcttttaaag atgggtgttc acatttacga acacgtatcg tcacgctgta
    38941 aatcgacaac tggttattca gtcccgccgc acgacgctgt tcataaccat cgcccagctt
    39001 cactgtcacc actttcggct ctgataccac attcatatcc gggcgcactt tccagtgaaa
    39061 cgtctccatt accgatatgc tccacttaac cgaccaccat cacgggcctg ctgttgcata
    39121 aagtccgctg ccgctttttt cccgaggtca taaaccacct tcagggcagc cggacctatc
    39181 tgcccgttcg tgccatcgtt attgatctcg atgttgtact gcggggcaaa catcgccata
    39241 cctgaaccac caatatccgc cacaaccccc agcttaccgt cagcaccacg acgcagtggc
    39301 agaatggctt caggtcccgc ttcccccatc acacccgcgc cttttgcaaa agcaaaaaac
    39361 gtcggacggt taaccaccgt gccactgtaa cgactcaaat cagcagactg ataaatcccc
    39421 ccattggcat tcagggaaag gctgctgaga tcaaatccca gtacactgcc aatccctttt
    39481 atcgatttca tcatggttgc ctgcgccagg attttcgcca tatctgacag cacagaagag
    39541 gtgaaggatt tgaaattgag tttgccggta gtgacaaaag ttgccaggcc atttcccatg
    39601 ttgctgaagg ctgacgagaa cacctgttct gctgttcctg ccgtattatc tgcatccacg
    39661 gtaaaatcct gaaatgcacg caggactccg tttttccagt taccctgcac aacttcaagc
    39721 tgttgccagt aacggcgatt ctcattcagt tgtcggttca ggctctccgt cagcgcctgc
    39781 tcggcctttc tgtagtcatc cgtgttatat gttcctttct gctcactatc ccgcctcaac
    39841 tgctccagct gttgctggta tttctggcga agactcagtt gtacctgata tcgctgccgc
    39901 tgctgatcac ccatacccac cgtggcgata tccaggtcat gttgctgacg ctgagcgcgc
    39961 tcttcttcag ccagttgact ggtcagctga attgtttttt tcttcagctc gttgagtgcc
    40021 gtctgtttct gaagctcctg ctgttttaca tccagcagcg tcagtgcctg aatcagttca
    40081 tctttacggg ccagcacact cttttcatct gccgtcagtt ttttcccgtc caggtcgctg
    40141 atgcgctgct gcagagccag aagctgttta tgcgcttctg tcatcctttc cgtggcaatg
    40201 cctgctgact gtctggcagc agcaatctgt ccttccacct gtgcctgttg ctgactgtac
    40261 tgcagcaata accgggtggc ctcatcatta cgggggtcgc gtgttttttt cttaccggat
    40321 gccagggctt tctcgtaacg ttcattttca cgttgtatcg ccgcatccct gacagcctga
    40381 tcggcgtact gcatggcatt aatacgcgca atttcacgct gatgtcgtgc tgcttccgtt
    40441 tcattcatcc ggttcagtgc agcattttca gcattacggc gtttctgttg ctcctgataa
    40501 ttccgctctg cctgctcttt tgcatcctgc aaatccttct ggcgtttttt ctcctgaagc
    40561 tcgttaagac gctgctgatc gtactcaacc tgagaagatg atgccgtcca ggggagtctt
    40621 ttcgcccgcg acactttctc ctgtaaagcg gaaatctgtt catccagcga gtcttcacga
    40681 ccaatattca tggccgcatc ccagaaacga ctccataaat cagacagata cttcagcgta
    40741 ctgcccagcg cattgaggtt attatcaata tccgcagtac gccgaccggt ttcctctgcc
    40801 agtgcagaca tggctatccg tgccgcatca ctggaccgcc cctgttcccc aaggacgcgt
    40861 atctgctcaa gctgagtggc agtaagaaaa tgcagctcat tgtccagagc cttcgcggca
    40921 tttacaggat catccttcag ccgcttaaac tgatttatgg tatcgctgac cgactggcca
    40981 accgatcgct ccatctgtgc ggcagctctc gccaccatac cgatatcgtt tccacgaaat
    41041 gcaccactcc ccaccacctg agccagcgca ccggctgcag catgttgcgt aataccattc
    41101 ccggaaatag cacgactgag cgtccacagc tgcccggcag tgactccggc ataatgcccc
    41161 gtcagcgaca actggcggtt aaattcttcc ccctccttct gaccatcata ccaggcttta
    41221 cccagaccat agacggccgc ggcaataccg ccaataaccc cgctcagcat catgcctttc
    41281 ggtgacatca gtgtgtctat ccatccggca cggttagcca gcgttatccc ggatcccctc
    41341 agcgcaccta aattgccgcg agccagttca cctatcagaa cgcctatctc ctggcgggcc
    41401 gctgcacttt tcagacccag cgaatgcgtg gcttttcctg cctgctccat tttgcggata
    41461 tacacttctg cagcactgct tacccccagc tgggcagcct tagcacgaag caactcagaa
    41521 gaagaaagat tctggcgggt tgcctgctct ttaagctgac ggataaacgc cactttctgt
    41581 cgggtagcct ctgcctcagc ctgcgtaaga acaccggttt tcgccgtaac ctcagaaatc
    41641 agcgccagat aatcctgctg accaatcccg ccactgtttc tggcctgtcg gatctgctgc
    41701 tgaatacgct gtaattcctg cagtcccgca ctggcctgtt tcacactgtc aatctgacga
    41761 taaaacgcgg cagccgcttt atcctgagcc tccgccagag ccatggcctg cgcctgttcc
    41821 tcgcgcattt tctggctcag tgcctccata cgctggcggg tttgctccac ctcgcgggcc
    41881 atgcgttcat gagcctgtgc gctcttctcc accgtctgcg catggacgga tgcggctgtt
    41941 gcagccgaag aagccgcctg cattgtctgc cgggcggcct gagtctgacg ctccataaaa
    42001 cgctgcatac gggcagaaga ccgttctgca tcgctggctg caccattcag aaggtttttg
    42061 atacggggaa tttcattttt aaactctgcc gcatcaatcc ccaaatcaat gaccaggttg
    42121 gctatctggt ccataacgca cacctccgga aataccttcc ccaagatgca tcagttcttc
    42181 gtccgttcgc tccggtatcc cgttctcttc cggtaaaagg ctgaaatcag ccaccgcagc
    42241 atcactgcta ccggacacca ttctcacgat caatgccttc agcgaggcaa actgcgcatc
    42301 catccacaca tcactgaagc tctgcatccg gaaataatcg ccccattcac caagctcagt
    42361 ggccgacatt tccgacagca tccgccgcca gtctgcccgc cggaactccc gggcaagccg
    42421 catgacaaac tgcatttccc gcgtcaggac ttttccggcg tcagcacctc atgctccaaa
    42481 tccccggcat tctcaatggc tcccataccg ctcagcgaca gaaccatctc cgcccccgct
    42541 cccagggcat catacgacca tgttgtaata acggatgcgc aaagcgtctc aacatcctga
    42601 gactgttccg cattccacag tgagcgggaa accagccagg cattgatatc catccccatc
    42661 cgcagaaaag caatctgtcg ttcagcctcc ggcagttctc cctcttcggc atcaaacttt
    42721 gccgttcgct gctgaacaaa cgccagatat tcaattctct gcagcccgga cagctcactg
    42781 agcaccacgg actgcttttc ataattaaac gagccctgtt tcagaaacat catgttctcc
    42841 acctgcaaaa aagccccgga taaccggggc aaatgatgag tatcgtcctg ttaacctgcg
    42901 gcgctgacag ccaccgcagc cacggccaca aaatcgccgt cagaagtcat gcccacaatg
    42961 ctgacactgc cctgcttcac gcctttcacc gtggccacaa gcccgttcag ggtcaccgtg
    43021 gcagtctgtg gatctgtcga atgcacactg atcgctttgt cactggctcc gtcaggtttt
    43081 actgtaaagg tcagcgtggt ggttgctccc acttttacac tggcagatgc cggtgccacc
    43141 gtcagcccgg taacgctcac tgtttcagtg ccttcctctg ccagatgcgg acgccccaca
    43201 ccgctgattt tcactgtgcg ggtcatcacg tcttttgagg caatggtttt acccagtgag
    43261 ctcagccagc cacggaaaac atcaacagtg ccgttgggat atttgatacg aaacgcgcag
    43321 acttcaccgg agtcgaacaa ctgaaccagt tttttctgcc cgctgtcacc cggacgccag
    43381 gccagcgtcg ccgaagtatc accgacggat ttctgcccct gggttgtcgt tttccagtct
    43441 gcatcttcat catcgagata agtgtcatct tctgcatcag cggtcatttc gccaggttgc
    43501 agatccttca ccatcgcaag acgcagccag tcagtgtccg ataaagggtt cgcaaacgca
    43561 tcgcccttgc cggtgtacat ccagaacgtc gttcccgcac ctttcgtttt tgccagtgga
    43621 tttggtgtgg tcattgccac ctcctttaat tcgtgtacgt gatctggtac gtgatttccg
    43681 ccatcgccca ggtggccatc tcattatcac gttgatagtt aaaaccgaga gggatcaggg
    43741 tgtcgatgag tccggaaagt gccggtatat cattcagagc cgggaaaatg gtgctctcca
    43801 tccacatatc cagctctgaa tccggtgcct gtgcccggat gaagacagca atatgcagaa
    43861 cagcctgcca gtcatcttca tccgtcattt ttccggtgta ctgagcatca ctcagccaca
    43921 ccgccacggc aggcagttcc tgcgcatcaa taaatgccgg aagcccgtca aaaaacgtgg
    43981 cgctgtctcc acactgttcc cgaaggcgtg ccagtacggc ctggcggatt tgtgtatgtc
    44041 ggttcatcgg gtcagccata acctcagttg ttgtttcagt gcatacccca gctgtttcgg
    44101 catttccgca gcaataatgc ggtcgcgggc atcttcaaat gcctgtgtca gcggtccgga
    44161 cagcgggact ttcaccacat caatggggta acgatttttg ccatcaatac gccgcatcac
    44221 atgccagcga ccattcgcca gttgctgaat aaacgcatcc cggaaaagat atttacccac
    44281 cttcagcaca ctgccacggt actgcagttt tccaccacgc cgggccagtc tgacctgggt
    44341 tgtccccagc ttaatagcgg gcagattgcc ccggttaacg cggatcctgg ccgtcatttt
    44401 tcctgacgga ctggctttaa acacccggac acgctgacgt accagtttca gggggatccc
    44461 tttcacctgg ttatctcccg caacggtatt cccggcaacc tgccgggtgg cgaccgagac
    44521 cgctttctgt gccacacggt ttatcgccca tgcgctggcc tgtggcacca tacgggtatc
    44581 aaggctgttc agattacgga tggcattctc aagccccttc atcccacacc tctttactca
    44641 ataaagatca ttggcttacc gttaaaacgt tcatgccgtg tgaccgtcca ttgttgtccg
    44701 tcataaacaa cgcgatcccc gcgccgtggg cggtatcccg aagaaaacac caccagagat
    44761 accgcaggtc cggacagagc attcagctct gccagtgttt ctcccgggat cacagtcata
    44821 tcggcatcat taatcgaggc tgtctttccc atctttctga ccgtgatcgc atccatacgc
    44881 gctgccagcc gggaaaaggg atcagacatt gagttttacc ggcacttctt ctgcactggt
    44941 tccggcatct gcccagacaa ccccgaccag cggatcagag ccgctgttag tcagctgaac
    45001 ttttccggac ttcagataaa ccttcttacc cgttttcatg tcatccgttt tcagcttagg
    45061 cagcataaac acaccttcgg tcatgccgtc gcctgtttca ccctgtggaa tatcggtcag
    45121 cgccaccgca aaaacatcac ccacctgcac cagatctccg ctgctgatgg ctgcactggc
    45181 aacaatcgcc accgtttttc cttcttctac aaaattcttt gccataactg tctccgcaca
    45241 gccccgttca ggggctgatt tcaggtacaa aaaaagccct tacgggccat cagagttgtt
    45301 gtctgcgacg tttacgccgt acatttcacc agaccgcggt gatcaactgg cgcgacaccg
    45361 gcgtcaatac gcactttcgt tgtcacgcca tccacactga agccctccat ctgatcaata
    45421 tatggcgtat ccacaccgtt gagataagcc acttcaatcg tatcggagcc ttttgacgca
    45481 gccaggtaga aggtggtctg gctgttatca tcaagacgag gctctgcaat aacggtcgca
    45541 aaatctttca ccgggttaat aataccggcg ttaatgtcag cccccttgac acttgaggag
    45601 cgaatgacct ggttagcaac agactccatc gccgtcggta ccagtacgaa cgcaggacga
    45661 atattcagat gacgctcccc ctctttctga acgcgcatca actggcgggc tttatccagc
    45721 gatgccacgt ccattgcagc gctctccagt acgtttgcat gtttcgcttt atcgaacaga
    45781 cttacattat ctgtggagat tttcgggtta gacgtcagaa tggcataaac cagatcggca
    45841 atagtggatt tcgccgcacg gcccagcttc atcgggacat cggtcagcat attcagatca
    45901 tcattgataa tggcctgacg ggtgatactg aacagctcgc cataggtcgc cagtgcaata
    45961 gtggcctgtt tatctccggt ggtgacgtat ttatattccg ccccttcacg cacctgacgc
    46021 agagcactga agccccccat acccacacga tgggcaattt taaaatcaga caactgacct
    46081 ttccgcgtcc actgttcata ggtttcaggg gcatcttccc agccctgcag aatggctttg
    46141 ttcgcaacat ccagcagaat attaccgaag tcagacgtac tgtgtgtgaa cgccgcaccg
    46201 accatctgca tcgggttata actggaaacc ccaatacccc gttcagtcag tgacatacgg
    46261 gcatattcac gcagggtcat cccgttgtag acattatcac gttcggtttt ttcaaatccg
    46321 gcacgcgcca tcagcgcctg gcggatcccg tcccccacaa aattaccgtt accggcataa
    46381 atatgagccg gggtattttt attggatggc gtggactcgc gccccatctc gttcaacagc
    46441 ttttcgcggg cctgctccag cgaacattca ggatcggcaa gacactgagc ctgcagcgtc
    46501 tgataacgcc cgccaaacat ggcaaacaga tcattaatac cgtttacacg cgctttttgc
    46561 tctgccagta cctgcgcacg gatgctgttt tcatccacca cgggtgctgc tgcctgcact
    46621 ggcgtccggg aggcttcagg ttcattatcc tgtacgcgtg gagcactgtt gcgtggcgga
    46681 gtaatcatgt ttcgaatgga ttccggcatc tttttaaatt cctctgtacg ttttgactga
    46741 atacatgcca ttgccttaac ggctggcgtt acctgatcag caaatccatg tgccagacat
    46801 tcggcaccgg acatccaggt ctcatccgcc agcatggcag caatttcatc ggtggttttc
    46861 ccggttttct gtgcataagc gggtaacaga accgcctcaa ctttatcgag caggtcggca
    46921 taggtgcgca tgtcctccgc atcaccgccc gtaaagccaa atggtttatg aatcatcatg
    46981 aaggtgtttt ccggcataat gaccgggttt cccaccatcg caatgaccga cgccattgac
    47041 gccgccacac cgtcgacata aacggtaatg gacgcaccat gtgttttcag cgcattaaaa
    47101 atggcgatgc cttcaaagac atcgccaccc ggtgaattaa tatggagatt aatgtgggtg
    47161 atatcgccca gtgcattcag atcactgata aactgcttcg ctgtaacacc ccagaaacca
    47221 atctcgtcat aaatataaat atccgcgtca ctctggtgac cagcctgcat cctgaaccag
    47281 gaattattct tcggactggt cgtcggtgtg ctgcggctcc tgtcgtttcg ttgcggcact
    47341 gctgcctcct ttatcactgg ccggatcggt atcaaatacc agatccagtt tgcggttttc
    47401 atcaatttcg gccttgcgcc gacgtttgac atcatccgga ttacgaccac cagcacgtac
    47461 ccagtctgat tctgtcgccg ctccaccacg aatctggatt ttccaggcct cagcctcctt
    47521 aacagggtca atccacggca tcaccggtcc ggaatacacc gcggtataca gtgaagaacg
    47581 gtcaagatcg cggggtagcc tgataacacc ggatgccaca gcctgtttca gccaggcacg
    47641 atacatcgga cgggtgacgg caccaataaa ccagtcctgc aggatcaggt agccatcagt
    47701 ggattcaacc agctcctgac gctgggcgct gtaagtgccg ttatagttgc gcgctgtact
    47761 ggaaaaactc agacgactgc ccgccgccac ggcacgcaac tgaccattac gaaaagtttc
    47821 aaggttagga ttggggcgat ccgacttcac cattccgatt tcttcgccgg gtttcagatc
    47881 atcgtaaata atgcctggct gaatggtaag ctcgcgttcc ttatccttgc tgccattacc
    47941 atccgcttca tagctctgcc cgtcgccttt ccggatgtac atccccagag cagcggcgat
    48001 ccttgctgca gtcagctcag aatcttcata ctctttcaga gcactgaggc ggatcagcac
    48061 accggacaat aaagacgtcc cgcgcatctg gtgcagacgg cgaacaaatt taagatgcag
    48121 cattcgctct gcatccactt ctttggtttc catctgccgt ccggatacgg gacggctttt
    48181 atacaccaga tatttttcgg gacgccccca gtaatcaaca aacacgccct gattcagcct
    48241 gttgctctca tcactggtca tgggaataaa gtccggctcg agcgcctcca gccagaaatg
    48301 aacaccggca gaaggcgtca ggctgtttat gcgcccggaa accatctggg caaacacctc
    48361 accatcgcgc agccaggtac gcagcatcag acgttccagc atcggacggg taaactgccc
    48421 ggtgacttcc gggctgacag accattcact ccatcgggtg cgaatctccg cagccagatc
    48481 acgggcaatg gccccattgc gtaataccgg atgtggctcg acaataatcc cgtttttccc
    48541 caccacccgt tcttccagct tgtcaaatac accaatgacc agatcgtggt tgttatcaag
    48601 gtaacgggcc tgctcacgta acgacacggc cccgtactgg cttaactggt cggcagttcg
    48661 gttttcccgc cgggctttgt gtgtccgcgt cgtttttacg gcctcataag cctggatcac
    48721 cgcccgggaa cgcagccttg ccgctttcca tcctggtgaa aaaacgccaa tcacatcatc
    48781 aagaattgcc atcagaacct cgccagccgg tacccgggat gcccccgtcg tcgtgtaatc
    48841 agagccgcaa ggcggcgctc ccactcctgc cgtccctgcc ggatctcaga taagttttcc
    48901 atggtcatct gctgaccatt aaaggtgacg gattttccgt ccagcaccgc catttcagct
    48961 tccgtataac gctgaatcat ggcttcgata tcattctggt tcataaccat cctccggaag
    49021 tcagccaggg gttaacatcg tcagttactg ttttcttccg tttttgtttt ttaacaggcg
    49081 tggataccgg ttccggtgag ggtgacggtt cgatactgtc cgggacacac tccagccagg
    49141 tttcccggct cgcccactcc ggtgcatccg gccagcggat cttttcgtat ccatgcagaa
    49201 tgaccagagc ctcggcatac accatcaggt caaaagcttc gttggcaccg cgacccggct
    49261 tactccattt cccgtcactg ctccgctctt catacgtcag ttcgtcgtaa aaccagctcc
    49321 ccagccagtc agggaaatgc acatagccgg gacctggcga gtcacgccat aacgcgttat
    49381 tcacccggtc tttcagtgca tccgtctgaa gaagccagag cggcacatca cctgcagcct
    49441 gcgcccgtcg gcccgttcgt ccggtgttat cagggaatgt acgggtgatc agttttgcgc
    49501 gccggatgct gtcgccctta aacaggtaaa tacgtttacc aaggccatca cgacggcaac
    49561 gacgccagaa tttataggca ttatcagtga ccccgtcttc accgccggag tccaccgcca
    49621 ttgccatcag tcgcatttgt tgagaaggat cggaggccag cggccagctt ttatgaaaaa
    49681 catccgtcag caggacatcc cagtcttccg gatagctggc cggatcaatt cgctggctct
    49741 ccccgtcgct gtcaccgcgc aatgactgcg tgatgttgta acgatcaata atccagcgtt
    49801 cgccacggct gccatagccc gttacctgaa ccacaaaacg gcgatgacgt cccgcctgca
    49861 catccactgt cgccacaaga aaattaacgc catccggcac actgcgggaa ggaactggct
    49921 ctgcccgctg ctcaagcagt tcactttttc gttgctccat gctggcgcgg ggaagataag
    49981 gtaatcccca gtcggtattg ataaccgtct tgagtgtttc ttcacttccg gttgtctcgt
    50041 attcctgttc tgcagtaagc agtttgtaaa cgagttgcga gagtgtctgg taagcagctg
    50101 ccggaccctc catccagaat gacgcaatac gtgagcgtcg gggatcacca taacgactgc
    50161 catccgcatt gatggattca ccatcccgca accagacccc acgtccgttc agctcacgtt
    50221 tttgttcagg cataatccgt cctgaacagg aaggacactg aatataagcc gcctcacttg
    50281 ccagcacggg atcggcaata tcacggaaac cagcaaccac atcgccgcag ggctgaaaat
    50341 actcaccaca gtgtggacag ggccagtacc agcgacggcg atcgccacgg ttatagagcg
    50401 acagtatccc cgtggttggt ggagcctcat gcggtgaagt ccgtcgccat ttcacatcct
    50461 tcacatccct gccgggggaa ctctccacca gcgtcatacc actggacata aatgttgtgg
    50521 tacgttttga ggcaagagag aaagcatccc cctcgccatc aatatcttcc ggaaaacggt
    50581 cataatccgt cagcgcgacg catttataat ctgatgagga catgatattg actgacggcc
    50641 agccgatttt caggtagtta ccagcaagga atgttctgtc ataaacgttg ttgtcatttt
    50701 tgttcggact caggcgactg accacttccg ggctgacgcg aaacgttctg gcgagtcgtt
    50761 ttttggagtg ttcgcgggct ttttcctccg tcatctgaat aatcagcata tcagcaggat
    50821 cgcaaatcac gttgtaaatc acccagccgt caatcaggcc gatagtcttg ccggttcgtg
    50881 ccgggccaac aaatatcact gcgtcgtatt cacgcgaggc caggcagttc atcggctcaa
    50941 taacatacgg tgccaccagc ggatcccacg ggactgagtt ccctgccccc atgggcaccc
    51001 gcatatactg agcaacggca tcagcaaccc gcattcgtct cggtgcgcga aggatataac
    51061 ctgaatcggt tcgtgctgcc tttgcggttt cctgattcag cattactcct cctgctgtaa
    51121 ttcctcctca tcatccgcac ctgcttcagt cacccgcagg gctatctgat cgcgcagatc
    51181 atcaataatg gactgaacac ggctcacagc ggcaggctgc agaccgcagt cacgttcaag
    51241 aatatccggt aatgtctcca gcacctgcac gaccgctttt gcccagatgg caaactcccg
    51301 tctgacatca ctggccggaa tgagttgtgc cgtttcctgt tcgaacttaa gacgctcacg
    51361 ttcagactga taccaggctt tgcgctcatg cgcgtccatt tcgccttctg caaccggcgg
    51421 tggtaatgcc agaaatgccg acacaatatc aaccacccga taaagcttga ggttgctttc
    51481 atgcccccct gcaacgggta gattttgcag ccttgccgca gcagtctggc gatgtacacc
    51541 tgacagtgcc gccagttgac taatattcag cgtcagattt tttaactctc gatccatacc
    51601 cgctccagaa tgttttaaac atgcatcttg cgaacaactt taggcaaacg gtgttggtga
    51661 tgaacaaaaa acaatcaaaa tcgacaccac aaaaata
//
LOCUS       DAFGPF010000020        50594 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFGPF010000020 DAFGPF010000000
VERSION     DAFGPF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 50594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50594
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.020"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            130..1530
                     /gene="sthA"
                     /locus_tag="LSX49_001411"
     CDS             130..1530
                     /gene="sthA"
                     /locus_tag="LSX49_001411"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HBL7167841.1"
                     /translation="MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTH
                     PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            complement(1513..2430)
                     /gene="oxyR"
                     /locus_tag="LSX49_001412"
     CDS             complement(1513..2430)
                     /gene="oxyR"
                     /locus_tag="LSX49_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HBL7167842.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(2697..4070)
                     /gene="argH"
                     /locus_tag="LSX49_001413"
     CDS             complement(2697..4070)
                     /gene="argH"
                     /locus_tag="LSX49_001413"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBL7167843.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYSNATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEDLPLSELQKFSLVIGEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLG"
     gene            complement(4131..4907)
                     /gene="argB"
                     /locus_tag="LSX49_001414"
     CDS             complement(4131..4907)
                     /gene="argB"
                     /locus_tag="LSX49_001414"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBL7167844.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGL
                     FLGDGDSIKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            complement(4915..5919)
                     /gene="argC"
                     /locus_tag="LSX49_001415"
     CDS             complement(4915..5919)
                     /gene="argC"
                     /locus_tag="LSX49_001415"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBL7167845.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDIGEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDVAFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     ATHLGADVIFTPHLGNFPRGILETITCRLKPGVSQVQVAQALQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            6073..7224
                     /gene="argE"
                     /locus_tag="LSX49_001416"
     CDS             6073..7224
                     /gene="argE"
                     /locus_tag="LSX49_001416"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HBL7167846.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQSVPGTRNKFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIMGQSGHSSDPSRGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHKLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            7526..10177
                     /gene="ppc"
                     /locus_tag="LSX49_001417"
     CDS             7526..10177
                     /gene="ppc"
                     /locus_tag="LSX49_001417"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HBL7167847.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GHEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            10360..12093
                     /locus_tag="LSX49_001418"
     CDS             10360..12093
                     /locus_tag="LSX49_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HBL7167848.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGT
                     HIKYKYRYPEDQGKFDGNTEHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAT
                     DPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            12319..13170
                     /locus_tag="LSX49_001419"
     CDS             12319..13170
                     /locus_tag="LSX49_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7167849.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGPVPDLAYQVDFPRLE
                     IVLEGEFIDTGAGAALVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQSQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(13157..13498)
                     /locus_tag="LSX49_001420"
     CDS             complement(13157..13498)
                     /locus_tag="LSX49_001420"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBL7167850.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCQLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQTHLILE"
     gene            complement(13500..14378)
                     /locus_tag="LSX49_001421"
     CDS             complement(13500..14378)
                     /locus_tag="LSX49_001421"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418387.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HBL7167851.1"
                     /translation="MTSSAGQRISCNVVETRRDDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDAAQARDVVKMNLQRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIKQIHLLPFHQYGEPKYRLLGKTWSMKEVAAPSSADVAT
                     MREMAERAGFQVTVGG"
     gene            complement(14344..16641)
                     /locus_tag="LSX49_001422"
     CDS             complement(14344..16641)
                     /locus_tag="LSX49_001422"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL7167852.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVIMRRA
                     KATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAASCT
                     DGPRREELLTIAEISRHNAEHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQTSLTQGEDPAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRLGTGIPQIF
                     NDEVVVPAFLNRGVLLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMIFDQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGAVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            complement(16692..17012)
                     /locus_tag="LSX49_001423"
     CDS             complement(16692..17012)
                     /locus_tag="LSX49_001423"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBL7167853.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            complement(17027..18106)
                     /locus_tag="LSX49_001424"
     CDS             complement(17027..18106)
                     /locus_tag="LSX49_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBL7167854.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGVMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICVPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAVTAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTEEKEDDLDLDFEIN"
     gene            18415..20916
                     /gene="ptsP"
                     /locus_tag="LSX49_001425"
     CDS             18415..20916
                     /gene="ptsP"
                     /locus_tag="LSX49_001425"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL7167855.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLVGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVAS
                     ANHFCEEFARSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQHQTIYIDG
                     NAGAIVVEPGESVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRQLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            20928..21590
                     /gene="fsa"
                     /locus_tag="LSX49_001426"
     CDS             20928..21590
                     /gene="fsa"
                     /locus_tag="LSX49_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBL7167856.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGMVKEAKRLRDAIPGIVVKIPVTSEGLAAIKMLKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTT
                     HL"
     gene            21601..22704
                     /gene="gldA"
                     /locus_tag="LSX49_001427"
     CDS             21601..22704
                     /gene="gldA"
                     /locus_tag="LSX49_001427"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HBL7167857.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            22980..23597
                     /locus_tag="LSX49_001428"
     CDS             22980..23597
                     /locus_tag="LSX49_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
                     /protein_id="HBL7167858.1"
                     /translation="MKASLALFSLLTVFTSYSLKSPAVPPTVVQIQANTNLAIADGAR
                     QQIGSTLFYDPAYVQLTYPGGDVPQERGVCSDVVIRALRSQKVDLQKLVHEDMAKNFA
                     AYPQKWQLKRPDSNIDHRRVPNLETWFTRHDKTRPTSKNPSDYQAGDIVSWRLDNGLA
                     HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFSWRMVGHYRYFAK"
     gene            complement(23624..24529)
                     /gene="yijE"
                     /locus_tag="LSX49_001429"
     CDS             complement(23624..24529)
                     /gene="yijE"
                     /locus_tag="LSX49_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HBL7167859.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKRI"
     gene            complement(24623..26803)
                     /gene="katG"
                     /locus_tag="LSX49_001430"
     CDS             complement(24623..26803)
                     /gene="katG"
                     /locus_tag="LSX49_001430"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HBL7167860.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGGGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(27132..28022)
                     /gene="metF"
                     /locus_tag="LSX49_001431"
     CDS             complement(27132..28022)
                     /gene="metF"
                     /locus_tag="LSX49_001431"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBL7167861.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRII
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLRRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            complement(28404..29957)
                     /locus_tag="LSX49_001432"
     CDS             complement(28404..29957)
                     /locus_tag="LSX49_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HBL7167862.1"
                     /translation="MKIKILAAGIALTLPFWACAKDVTIIYTNDLHAHVEPYKVPWIA
                     DGKRDIGGWANITTLVKQEKAKNKATWFFDAGDYFTGPYISSLTKGKAIIDIMNTMPF
                     DAVTIGNHEFDHGWDNTLLQLSQAKFPIVQGNIFYQNSSKSFWDKPYTIIEKDGVKIG
                     VIGLHGVFAFNDTVSAATRVGIEARDEIKWLQRYIDELKGKVDLTVALIHEGVPARQS
                     SMGGTDVRRALDKDIQTASQVKGLDILITGHAHVGTPEPIKVGNTLILSTDSGGIDVG
                     KLVLDYKEKPHNFTVKNFELKTIYADEWKPDPQTKQVIDGWNKKLDEVVQQTVAQSPV
                     ELKRAYGESASLGNLAADALLVAAGKNTQLALTNSGGIRNEIPAGAITMGGVISTFPF
                     PNELVTMELMGKQLRSLMEHGASLSNGVLQVSKGLEMKYDSNRPVGQRVITLTLNGKP
                     IEDATVYHIATQSFLADGGDGFTAFTEGKARNTTGGYYVYHAVVDYFKAGNTITDEQL
                     NGMRVKDIK"
     gene            30090..31220
                     /locus_tag="LSX49_001433"
     CDS             30090..31220
                     /locus_tag="LSX49_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBL7167863.1"
                     /translation="MSTLFTINACKSFGCRNLGQPTSTDYSWPDYRLGYPALHCRACG
                     SYPPLFDEQQFRDWLTVHLSTFATEKGHFCPVCYGTETICYGHNPQGSQRIQCRNCKK
                     VWTPKQYQKEITTPEIIETVALLVPFQGVSSGQKLYVLISFDALRGNILHLSTNYTQH
                     QAGESLHYRYRGNAEPELHDNNIVQRVDMREAQFLRRSQFDEIQYGSAALKRNAKGAI
                     LRPVITAHGHFRVLNILFPTVKTHVISHECFLRGAIITAWADLFRQQQGEIWFIEEEI
                     ADDTDNMPWRFQGKTYHGWWKNQWQLWVQGKNRKMVCALTGGKSSKAEMLSLATSRHF
                     IDWLHKQAVFTHSAPLSAGRVTQILLSLAQDYNNCASRLISD"
     gene            complement(31184..33616)
                     /gene="metL"
                     /locus_tag="LSX49_001434"
     CDS             complement(31184..33616)
                     /gene="metL"
                     /locus_tag="LSX49_001434"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HBL7167864.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADNLISAF
                     VSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPSAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(33619..34779)
                     /gene="metB"
                     /locus_tag="LSX49_001435"
     CDS             complement(33619..34779)
                     /gene="metB"
                     /locus_tag="LSX49_001435"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBL7167865.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQSDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            35056..35373
                     /gene="metJ"
                     /locus_tag="LSX49_001436"
     CDS             35056..35373
                     /gene="metJ"
                     /locus_tag="LSX49_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HBL7167866.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            35433..36041
                     /locus_tag="LSX49_001437"
     CDS             35433..36041
                     /locus_tag="LSX49_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HBL7167867.1"
                     /translation="MKIRLLIPGLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     SDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEDSKYIVRRVKGELNAEQQQK
                     LAQTAKRYLGKPYDSSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSNPLV
                     QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            complement(36102..36314)
                     /gene="rpmE"
                     /locus_tag="LSX49_001438"
     CDS             complement(36102..36314)
                     /gene="rpmE"
                     /locus_tag="LSX49_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBL7167868.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            36517..38715
                     /gene="priA"
                     /locus_tag="LSX49_001439"
     CDS             36517..38715
                     /gene="priA"
                     /locus_tag="LSX49_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBL7167869.1"
                     /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGSRVRVPFGKQQERIG
                     VVVSVSDVSELPLNELKAVVEVLDVEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQQHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDDFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILASPLADDKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIINGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            38871..39896
                     /gene="cytR"
                     /locus_tag="LSX49_001440"
     CDS             38871..39896
                     /gene="cytR"
                     /locus_tag="LSX49_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HBL7167870.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSRAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            39988..40947
                     /gene="ftsN"
                     /locus_tag="LSX49_001441"
     CDS             39988..40947
                     /gene="ftsN"
                     /locus_tag="LSX49_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HBL7167871.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            41040..41570
                     /gene="hslV"
                     /locus_tag="LSX49_001442"
     CDS             41040..41570
                     /gene="hslV"
                     /locus_tag="LSX49_001442"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HBL7167872.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            41580..42911
                     /gene="hslU"
                     /locus_tag="LSX49_001443"
     CDS             41580..42911
                     /gene="hslU"
                     /locus_tag="LSX49_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HBL7167873.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL"
     gene            42978..43904
                     /gene="menA"
                     /locus_tag="LSX49_001444"
     CDS             42978..43904
                     /gene="menA"
                     /locus_tag="LSX49_001444"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBL7167874.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGAVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            43997..44482
                     /gene="rraA"
                     /locus_tag="LSX49_001445"
     CDS             43997..44482
                     /gene="rraA"
                     /locus_tag="LSX49_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HBL7167875.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(44567..44812)
                     /gene="zapB"
                     /locus_tag="LSX49_001446"
     CDS             complement(44567..44812)
                     /gene="zapB"
                     /locus_tag="LSX49_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HBL7167876.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            45237..46082
                     /gene="glpF"
                     /locus_tag="LSX49_001447"
     CDS             45237..46082
                     /gene="glpF"
                     /locus_tag="LSX49_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HBL7167877.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            46105..47613
                     /gene="glpK"
                     /locus_tag="LSX49_001448"
     CDS             46105..47613
                     /gene="glpK"
                     /locus_tag="LSX49_001448"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBL7167878.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGMEEYIRNNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            47784..48794
                     /gene="glpX"
                     /locus_tag="LSX49_001449"
     CDS             47784..48794
                     /gene="glpX"
                     /locus_tag="LSX49_001449"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HBL7167879.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            48891..49637
                     /gene="fpr"
                     /locus_tag="LSX49_001450"
     CDS             48891..49637
                     /gene="fpr"
                     /locus_tag="LSX49_001450"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HBL7167880.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIE
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPDCETLWMLATGTAIGPYLSILQLGKDLERFKNMVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESAVGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(49642..50070)
                     /gene="uspD"
                     /locus_tag="LSX49_001451"
     CDS             complement(49642..50070)
                     /gene="uspD"
                     /locus_tag="LSX49_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HBL7167881.1"
                     /translation="MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKLSADLLIVPFIDK"
     gene            complement(50097..50396)
                     /locus_tag="LSX49_001452"
     CDS             complement(50097..50396)
                     /locus_tag="LSX49_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HBL7167882.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAAASSADEGASVAYKIKDLEGQVELDAAFTFSCQAEMIIFELSLRSLA"
BASE COUNT        12213 a        13670 c        13017 g        11694 t
ORIGIN      
        1 aagaaggagg aagacaaagc aaaggccgct cacgatatag ccagataaat gacggggatc
       61 aattggctta cccgcgataa aatgttacca ttctgttgct tttatgtata agaacaggta
      121 agccctacca tgccacattc ctacgattac gatgccatag taataggttc cggccccggc
      181 ggcgaaggcg ctgcgatggg cctggttaag caaggtgcgc gcgtcgcagt tatcgagcgt
      241 tatcaaaatg ttggcggcgg ttgcacccac tggggcacca tcccgtcgaa agctctccgt
      301 cacgccgtca gccgcattat agaattcaat caaaacccac tatacagcga ccattcccga
      361 ctgctccgct cttcttttgc cgatatcctt aaccatgccg ataacgtgat taatcaacaa
      421 acgcgcatgc gtcagggatt ttacgaacgt aatcactgtg aaatattgca ggggaacgct
      481 cgctttgttg atgagcatac gttggcgctg gattgcccgg acggcagcgt cgaaacacta
      541 actgctgaaa aatttgttat tgcctgcggt tctcgtccat atcatccaac agatgttgat
      601 ttcacccatc cacgcattta tgacagcgac tcaattctta gcatgcacca cgaaccgcgc
      661 catgtactta tttacggtgc tggagtgatc ggctgtgaat atgcgtcgat cttccgcggt
      721 atggatgtaa aagtggatct gatcaacacc cgcgatcgcc tgctggcatt tctcgatcaa
      781 gagatgtcag attctctctc ctatcacttc tggaacagtg gcgtagtgat tcgtcacaac
      841 gaagagtacg agaagatcga aggctgtgat gacggtgtga tcatgcatct gaagtcgggt
      901 aaaaaactga aagctgactg tctgctctat gccaacggtc gcaccggtaa taccgattcg
      961 ctggcgttac agaacattgg gctggaaact gacagtcgcg gacagctgaa ggtcaacagc
     1021 atgtatcaga ccgcacagcc gcacgtttac gcggtgggcg acgtgattgg ttatccgagc
     1081 ctggcgtcgg cagcctatga ccaggggcgc attgccgcgc aggcgctggt gaaaggtgaa
     1141 gccaccgcac atctgattga agatatccct accggcattt acaccatccc ggaaatcagc
     1201 tctgtaggca aaaccgaaca gcagctgacc gcgatgaaag tgccatatga agtaggccgc
     1261 gcccagttta aacatctggc acgtgcacaa atcgtcggca tgaacgtggg cacgctgaaa
     1321 attttgttcc atcgggaaac aaaagagatt ctgggtattc actgctttgg cgagcgcgct
     1381 gccgaaatta ttcatatcgg tcaggcgatt atggaacaga aaggtggcgg caacactatt
     1441 gagtacttcg tcaacaccac ctttaactac ccgacgatgg cggaagccta tcgggtagct
     1501 gcgctaaatg gcttaaaccg cctgttttaa cactttatcg aaatggccat ccattcttgc
     1561 gcggatggcc tctgccagct gctcatagcg gctgcgcagc ggtgagccag gacgataaac
     1621 caggccaata gtgcggcgtg gttccggctt aatgcacggc agataaacaa ccccatcgcg
     1681 tttgcgttcc ggcggcacag ccagcgcagg cagtaaagtg atcccgctac ctgccgccac
     1741 catgttgcgc agagtttcca ggctggtcgc gcggaagtgt gtatcttcat ccgccccggc
     1801 ttcaaaacag aaacccattg cctgatcgcg caaacagtga ccatcttcca gcatcagcag
     1861 tttttcccct gccagatcgg ccatcggtac gcattcgcgg ttcgcccacg ggtggtcttc
     1921 atagatagcc agcaacattg gctcatcaaa caacggcact tcaatgaatg cttcgctctc
     1981 tttcaccagc gcgaggatca cgcaatcgag tttgccgctg tccagttgcg ccagtaactg
     2041 gtgggtctgt gcttcatgca gatacatttc cagctttgga aaggtctggt gcagcatcgg
     2101 gataatatgc ggtagcaggt acggtccaac cgtgggaatc aaaccaatat gcagcggtcc
     2161 ggacatcgtc tcgccctgct ggcttgccat ctctttaagg actttcacct cacgcagcac
     2221 ggtacgcgcc tgatccacca gcagcattcc cgcctgggtg aataacactt tacggctggt
     2281 ccgctccagc aacatcacgc ccagctcatc ttccagctta cgaatttgcc cgctaagcgt
     2341 cggctggcta acgtggcagg aatctgccgc acgccgaaaa tggcggtgtt cagccaatgc
     2401 caccaggtac tcaagatcac gaatattcat tatccatcct ccatcgccac gatagttcat
     2461 ggcgataggt agaatagcaa tgaacgatta tccctatcaa gcattctgac tgataattgc
     2521 tcacagaaac ggagcggcac ctcttttaac ccttgaagtc acagcccgtt tcgagagttt
     2581 ctcagctcga ataactaaag ccaacgtgaa cttttgcgga tctccaggat ccgctttttt
     2641 ttgccataaa aaagcccagc gataagccag gctcaaattt atacatataa atgttcttac
     2701 cccaaccgcg cctgcgcaaa agcaatcgcc tgcgccacct gttgcggtga gacaccgcct
     2761 tttgccgcac gcttgtcgag gcacgattgc agcgacagaa tcggatagac atcttcgcca
     2821 atcaccaggc tgaatttctg caactcactg agtggcagat cttccagcgg tttgccctga
     2881 cgaatggctt ccaccaccgc ttcacccaca atatggtgcg cctcgcggaa cggtacgcct
     2941 ttcgccacca gataatccgc cagttcagta gcgttggagt aaccctgctg cgccgcttcc
     3001 tggcaacgcg gacgtttcac ctgaatgccg tccagcacca gcgccgccat atgcaggcag
     3061 tccagccagg tatcgagcgc gtcgaacaga ccttctttgt cttcctgcat atctttgttg
     3121 taagccagcg gcaaaccttt cagcgtcatc atcatgccgg ttaacgcccc ctgcacccga
     3181 ccgcatttac cgcgaatcag ctccagcgca tccgggtttt tcttctgcgg cattaatgat
     3241 gaaccggaag tcacacggtc agaaagctcc acaaaccccg cttcgccggt gttaaagaaa
     3301 atcagatctt cagcaaaacg cgacagatgc accatgccga tagcggcagc agaaagcagt
     3361 tccaacacat ggtcacggtc agaaacgctg tcgagactgt tacgggtcgc cgaagcaaag
     3421 cccagccaac ctgctaactg ttcacggtcg atttcatagg ccgttcctgc cagtgcgcca
     3481 cagcctagcg ggctgacatc cagacgctta agcgcatcct gcaaacggct ttcatcacgc
     3541 gccagcatct caacgtaggc caggcaccag tgcgcgaacg tcaccggctg ggcgcgttgc
     3601 aggtgggtgt aacccggcat caccgcgtcc tgattgttct gcgcggtctc gaccagagcg
     3661 gattgtaact gccggttagc cgtcagcaac tcgctaacgg tatctttgca ccacagtttc
     3721 aggtcagttg ctacctgatc attacggcta cgcccggtat gcaatttttt gcctaactga
     3781 cccactttgt cgatcagttt gccttccacc cagctatgga tatcttcggc gtcgctttca
     3841 aggatttgtt gtggcctggc gcgaacatct tccagcagca cgttcagcgc ctcttccagt
     3901 tgcgcctgct cttctgcggt taacacgccg accgttacca gggctttgga ccaggccaca
     3961 gagccaacaa tatcctgctc cgccagacgg taatcaaagc gcagtgagtc gttgaattgt
     4021 ttgaaccgtt gatctgctgc ctgggtaaaa cgcccgcccc aaagtgccat aactctgttt
     4081 ccttattttg aaattcaatg ccggaaagct gcgcctccgg ccaacaaaac ttaagctaaa
     4141 atccgcgtcc ccatcggcat accgttaaac agtgccggaa gctgttccgc atgacgccag
     4201 gaggcgatat ctaccggacg gcccaacgtg cgcgcagcat ccagcgccgc gttcactttc
     4261 acaatcatgc cgtcagtaat aatgccctgc tcaatcagtt gttctgcttt cgcggcggtc
     4321 atttcggcaa tacgttgccc tttgccgtcg agaatgccgc tgacgtcaga gagcaaaatc
     4381 agatccgcgc ccagcgttgc cgccagcgcc gtcgccgcct ggtcggcatt gacgttcatc
     4441 agttgccctt cgtctgttac gccaatggag ctgaccaccg gcagataacc gttctccagc
     4501 aaactgttga taagcttagg cgaacctggc tgcgccagtc caacatggcc taactcttca
     4561 tcaagctggg tcactttgat gctgtcgccg tcaccgagaa acaaacctac ggccgcaatc
     4621 tgatgtttct tcgcccatgc cagcagggtt ttatttgccg ttcccgccag tgctccggtg
     4681 ataatgtcta tctgatccgc aggcgtcacc cgcaggccat ttttcttttt caccggcaga
     4741 ttcagccctt tcatcagctc atccaccaca caaccgccgc cgtgcacaat caccagcgga
     4801 cgctgatgtg actcgcgata attcaccagt gcgctaaaca gacgttccag cgcctcttca
     4861 ctatccagca gtacgccacc cagtttgata attaatggat tcatcattgc acccttaaat
     4921 aagagactgc gtttccgcat agccgaaacg aatattggcg cactgcaccg cttgtgccgc
     4981 cgcgcctttc agtaagttgt cttcggtcgc cacaataatc agatgctcgc cctgaacggc
     5041 aaaaccgata tcgcagaatg gcagtccaac gacatttttc agcgccggaa cgcctttgtc
     5101 atacagccgc accagtggtt tatgggcata cgcctgctgt aacgcttgcg ccacttgcac
     5161 ctggctcaca cccggtttca ggcggcaggt aatggtttcg agaatgccgc gcgggaaatt
     5221 gcccagatgc ggggtgaaga taacgtcagc accgaggtgt gtggcgatct ctggttgatg
     5281 gcgatgggta aagacgccat acggttgcag gctaacttca caaaaactat ttgaaatcgc
     5341 tgccttacgt cctgcaccgc tcacgccgct ggtggcgttg atcaccggcc actgattgag
     5401 gtcaagaaga tcggcatcaa tcaacggttt cagcgccagc tgtgctgccg tcggataaca
     5461 gcctggcacg gcaatcaagt tcgcttcttt taatttatta ccgcaccact ccgccagacc
     5521 gtaggctgcc tgttccagca gttccgggta ttgatgggta aagccgtaat atttttcata
     5581 gaaggcgaca tcgttaacac gaaacgcgcc ggaaaggtcg aacaccacac agcctgcttc
     5641 aagaaattgc ggcgctaaat cgtggctgac ttcatgggcg gtggcgagaa acaccacgtc
     5701 cacccctggg ctaaactcgc cgatatccga catcggctgc aacggcagat caacgatgcc
     5761 ttttagctgc ggatgcaaat cggagattaa ctttcccgca tcattgcttt gcgctgaaac
     5821 agtcaaagcg gttatgttca tatgcggatg gcgatttaca taggtcacta gctctgcgcc
     5881 agcgtagcca ctggcaccca caatcagcgt attcaacatc ggggctattc accttcttat
     5941 gtctggttgc caggttaaac gtaaaacatt caccttacgg ctggtgggtt ttattacgct
     6001 caacgttagt gtatttttat tcataaatac tgcatgaata ttgatactat catgaccaga
     6061 ggtgtgtcaa caatgaaaaa caaattaccg ccatttatcg agatttaccg tgctctgatt
     6121 gccacacctt caataagcgc cacggaagag gcactcgatc aaagcaatgc agatttaatc
     6181 actctgctgg cggactggtt taaggattta ggcttcaatg tggaagtgca gtctgtgcca
     6241 ggaactcgca acaaatttaa tatgctggcc agttgcggac agggggctgg cggtttgttg
     6301 ctggcggggc ataccgatac ggtgccattt gatgacggac gctggacgcg cgatccattt
     6361 acgttgacgg agcatgacgg caagctttac ggcttaggca ccgccgacat gaaaggcttt
     6421 tttgcgttta tccttgatgc gctacgcgat gtcgacgtca cgaagcttgc aaaaccgctc
     6481 tacattctgg cgactgccga tgaagaaacc agtatggccg gagcgcgtta ttttgccgaa
     6541 actaccgccc tgcgcccgga ttgcgccatc attggcgagc caacgtcgct gcaaccggta
     6601 cgcgcacata aaggccacat ctcaaatgcc attcgaatta tgggtcagtc gggccactcc
     6661 agcgatccgt cgcgcggggt taacgctatc gaactgatgc acgacgccat cggccatatt
     6721 ttgcaattgc gcgataacct gaaagaacgc tatcactatg aagcgtttac cgtgccatac
     6781 cccacactca acctcgggca tattcacggc ggcgacgcct ctaaccgtat ttgcgcttgt
     6841 tgtgagttgc atatggatat tcgtccgctg ccaggcatga cactcaatga acttaatggt
     6901 ttgctcaacg atgcattggc tccagtgagc gaacgctggc cgggtcgtct gacggtcgac
     6961 gagctgcacc cgccgatccc tggctatgaa tgcccaccga atcataaact ggttgaagtg
     7021 gttgagaaat tgctcggagc aaagaccgaa gtggtgaatt actgtaccga agcgccgttt
     7081 attcaaacgt tatgcccgac gctggttctg gggcctggct caattaatca ggctcatcag
     7141 cctgatgaat atctggagac gaggtttatc aagcccaccc gcgaactgat cacccaggtg
     7201 attcaccatt tttgctggca ttaaaacgta ggccaaacaa tgtcggatgc gatgcttgcg
     7261 catcttatcc gacctacacc tttggtgtta ctcgaggcga ttttttaaca ttcccataag
     7321 ttacgcttat ttaaagcgtc gtgaatttaa tggcgtaaat tcctgctatt tattcgtttg
     7381 ctgaagcgat ttcgcagcat ttgacgtcac cgcttttacg tggctttata aaagacgacg
     7441 aaaagcaaag cccgagcata ttcgcgccaa tgcgacgtga aggatacagg gctatcaaac
     7501 gataagatgg ggtgtctggg gtaatatgaa cgaacaatat tccgcattgc gtagtaatgt
     7561 cagtatgctc ggcaaagtgc tgggagaaac catcaaggat gcgttgggag aacacattct
     7621 tgaacgcgta gaaactatcc gtaagttgtc caaatcttca cgcgctggca atgatgctaa
     7681 ccgccaggag ttgctcacca ccttacaaaa tttgtcgaac gacgagctgc tgcccgttgc
     7741 gcgtgcgttt agtcagtttc tgaacctggc caacaccgct gagcaatacc acagcatttc
     7801 gccgaaaggc gaagctgcca gcaacccgga agtgatcgcc cgcaccctgc gtaaactgaa
     7861 aaaccagccg gaactgagcg aagacaccat caaaaaagca gtggaatcgc tgtcgctgga
     7921 actggtcctc acggctcacc caaccgaaat tacccgtcgt acactgatcc acaaaatggt
     7981 ggaagtgaac gcctgtttaa aacagctcga taacaaagat atcgccgact acgaacacaa
     8041 ccagctgatg cgccgcctgc gccagttgat cgcccagtca tggcataccg atgaaatccg
     8101 taaactgcgc ccaagcccgg tagatgaagc caaatggggc tttgccgtag tagaaaacag
     8161 cctgtggcaa ggcgtaccga attacctgcg cgaactgaac gaacaactgg aagagaacct
     8221 cggctacaaa ctgcccgtcg aatttgttcc ggtacgtttt acctcgtgga tgggcggtga
     8281 ccgcgacggc aatccgaacg tcactgccga tatcacccgc cacgtcctgc tactcagccg
     8341 ctggaaagcc accgatttgt tcctgaaaga tattcaggtt ctggtttctg aactgtcgat
     8401 ggttgaagcc acccctgaac tgctggcact ggttggcgaa gagggtgccg cagaaccgta
     8461 tcgctatctg atgaaaaacc tgcgttctcg cctgatggcg acacaggcat ggctggaagc
     8521 gcgcctgaaa ggcgaagaac tgccaaaacc agaaggtctg ctgacacaaa acgaagaact
     8581 gtgggaaccg ctctacgctt gctaccagtc acttcaggcg tgtggcatgg gtattatcgc
     8641 caatggcgat ctgctcgaca ccctgcgccg cgtgaaatgt ttcggcgtac cgctggtgcg
     8701 tattgatatc cgtcaggaga gcacccgcca taccgaagcg ctgggcgagc tgacccgcta
     8761 cctcggtatc ggcgactacg agagctggtc agaagccgac aaacaggcgt tcctgatccg
     8821 cgaactgaac tccaaacgtc cgcttctacc gcgcaactgg caaccaagcg ccgaaacgcg
     8881 cgaagtgctc gatacctgcc aggtgattgc cgaagcgccg caaggctcca ttgccgccta
     8941 cgtgatctcg atggcgaaaa cgccgtccga cgtgctggct gtccacctgc tgctgaaaga
     9001 agcgggtatc gggtttgcga tgccggttgc tccgctgttt gaaaccctcg atgacctgaa
     9061 caacgccaac gatgtcatga cccagctgct gaatatcgac tggtatcgcg gcctgattca
     9121 gggcaaacag atggtgatga ttggctattc cgactcagca aaagatgcgg gcgtgatggc
     9181 agcttcctgg gcgcaatatc aggcacagga tgcattaatc aaaacctgcg aaaaagcggg
     9241 tattgagctg acgttgttcc acggtcgcgg cggttccatt ggtcgcggcg gcgcacctgc
     9301 ccatgcggcg ctgctgtcac aaccgccagg aagcctgaaa ggtggcctgc gcgtgaccga
     9361 acagggcgag atgatccgct ttaaatatgg tctgccagaa atcaccgtca gcagcctgtc
     9421 gctgtacacc ggggcgattc tggaagccaa cctgctgcca ccgcctgagc cgaaagagag
     9481 ctggcgtcgc attatggatg aactgtcagt catctcctgc gatctctacc gtggctacgt
     9541 acgtgaaaac aaagattttg tgccttactt ccgctccgct acgccggaac aagaattggg
     9601 taaactgccg ttgggttcac gtccggcgaa acgtcgcccg accggcggcg tcgagtcgct
     9661 gcgcgccatt ccgtggattt ttgcctggac gcaaaaccgc ctgatgctcc ccgcctggct
     9721 gggtgcaggt acggcgctgc aaaaagtggt cgaagatggc aaacagagcg agctggaagc
     9781 catgtgccgc gattggccat tcttctcgac gcgtctcggc atgctggaga tggtcttcgc
     9841 caaagcagac ctgtggctgg cagaatacta tgaccaacgc ctggtcgaca aagcactgtg
     9901 gccgttaggt aaagagttac gcaatctgca agaagaagac atcaaagtgg tgctggcgat
     9961 tgccaacgat tctcacctga tggccgatct gccgtggatt gcagagtcta ttcagctacg
    10021 gaatatttac accgacccgc tgaacgtatt gcaggccgag ttgctgcacc gctcccgcca
    10081 ggcagaaaaa gaaggccatg aaccggatcc tcgcgtcgag caggcgttaa tggtcactat
    10141 tgccgggatt gcggcaggta tgcgtaatac cggctaatct tcctctcctg caaaccctcg
    10201 tgcttttgcg cgagggtttt ctgaaatact gctgttctaa caccctcgtt ttcaatatat
    10261 ttctgtctgc attttattca aaatctggat atcccttcag atatccttaa ggaattgtcg
    10321 ttacattcgg cgatattttt ttcaagacag gttcttacta tgcattccac agaagtccag
    10381 gctaaacccc tttttagctg gaaagccctg ggttgggcac tgctctactt ttggtttttc
    10441 tctactctgc tacaggccat tatttacatc agtggttata gtggcactaa cggcattcgc
    10501 gactcgctgt tattcagttc gctgtggttg atcccggtat tcctctttcc gaagcggatt
    10561 aaaattattg ccgcagtgat cggcgtggtg ctatgggcgg cctctctggc ggcgctgtgc
    10621 tattacgtca tctacggtca ggagttctcg cagagcgttc tgtttgtgat gttcgaaacc
    10681 aacaccaacg aagccagcga gtatttaagc cagtatttca gcctgaaaat tgtgcttatc
    10741 gcgctggcct atacggcggt ggcagttctg ctgtggacac gcctgcgccc ggtctatatt
    10801 ccaaagccgt ggcgttatgt tgtctctttt gccctacttt atggcttgat tctgcatccg
    10861 atcgccatga atacgtttat caaaaacaag ccgtttgaga aaacgttgga taacctggca
    10921 tcgcgtatgg agcctgccgc accgtggcaa ttcctgaccg gctattatca gtatcgtcag
    10981 caactaaact cgctaacaaa gctactgaat gaaaataatg cattgccgcc gctggctaat
    11041 ttcaaagatg aatcgggtaa cgaaccgcgc accttagtgc tggtaattgg cgaatcgacc
    11101 cagcgtggac gcatgagcct gtacggttat ccgcgtgaaa ccacgccgga gctggatgcg
    11161 ctgcataaaa ccgatccgaa tctgaccgtg tttaataacg tggttacgtc tcgtccgtac
    11221 accattgaaa tcctgcaaca ggcgctgacc tttgccaatg aaaagaaccc ggatctgtat
    11281 ctgacgcagc cgtcgctgat gaacatgatg aaacaggcgg gttataaaac cttctggatc
    11341 accaaccagc agacaatgac cgcccgcaat acgatgctga cggtattttc gcgccagacc
    11401 gacaagcagt actacatgaa ccagcaacgt acgcagagtg cgcgtgaata cgacaccaac
    11461 gtgctgaagc cgttccagga agtgctgaag gaccctgcgc cgaagaaact gatcatcgtt
    11521 catctgctgg gtacgcatat caagtacaag taccgttatc cggaagatca gggcaaattt
    11581 gacggtaata cagagcatgt tccaccggga ttaaacgcag aagagctgga gtcatataat
    11641 gattatgaca atgctaacct gtacaacgat cacgtggttg ccagcctgat taaagacttt
    11701 aaagcgaccg atccgaacgg tttcctggtt tatttctctg accacggtga agaggtttac
    11761 gacacgccgc cgcacaaaac tcaggggcgt aatgaagaca atccgacgcg tcatatgtac
    11821 accattccgt tcctgctgtg gacgtcagaa aaatggcaag cgactcatcc gcgtgatttc
    11881 tcacaggatg ttgatcgtaa atacagcctg gcggaactga tccacacctg gtcagatttg
    11941 gcgggcttat cttacgacgg ttacgatcca acccgttcag tggtgaatcc gcagttcaaa
    12001 gaaactaccc gctggattgg taacccgtat aagaaaaacg cactgatcga ttacgacact
    12061 ctgccgtatg gcgatcaggt gggtaatcag taattatcag ccagatgtta tttgccggat
    12121 gcgacgcttg acgcgtctta tccggcctac agatcgcggc ggtaggccgg ataaggcgtt
    12181 tacgccgcat ccggcaatac aagtcgactg aaactgccgc aatgtttaca tctcactccc
    12241 atcaggccac acttttcagg tggccttttt tcataatgcc agttactgtt ttcccgtcta
    12301 catacctaag ggaataacat gtatcacgac gtcagctatc tgctctcccg cctgatcaac
    12361 ggcccgctgt ccctgcgcca gatttacttt gccagcagca acggcccggt gcccgatctt
    12421 gcgtatcagg tcgattttcc acgtctggaa attgtgctgg aaggtgagtt tattgatacc
    12481 ggcgctggag cagcgttagt tcccggcgat gtgctgtacg tccctgctgg tggctggaat
    12541 tttccacaat ggcaagcccc cgccacgacc tttagcgtgc tatttggcaa acagcaactc
    12601 ggcttcagcg tcgtgcaatg ggatggcaaa caatatcaaa atctggcgaa gcaacacgtc
    12661 gcccgacgcg gcccacgcat tggttctttt ctgctacaaa cgctcaatga aatgcaaatg
    12721 cagtcgcagg agcagcaaac ggccagactt atcgtcgcca gcctgcttag ccactgccgc
    12781 gatttgctcg gcagccaaat acagaccgcc tcacgcagcc aggctctatt cgaagctatt
    12841 cgtgattata tcgacgaacg ctatgcctcc gcacttaccc gcgaatctgt cgcacaggcg
    12901 ttctatattt cgccaaatta cctctcgcac ctgtttcaaa aaacgggggc cattggtttt
    12961 aacgaatacc tgaatcacac gcgactggag cacgctaaga cattattgaa aggctatgac
    13021 ctgaaggtaa aagaagtggc gcacgcctgc ggctttgtcg acagcaacta cttctgccgt
    13081 ctgtttcgta aaaataccga acgctcgccg tcggaatatc gtcggcagta ccacagccaa
    13141 ctgacagaaa aaccgactac tccagaataa gatgggtttg ctgcggcgca gaaagcactt
    13201 tgcgcactgc gctcatcacc ctctgcggct cacgcaggaa agcgtagatg ctgcattgca
    13261 cgtagcgaca atgttcaaat cgctcagcac cggcaagctc gatatccgta attaacagcg
    13321 caacatccgc ccggcggata tcctcgtccg ctaaacgatt ctccgttccc aacgcgccct
    13381 gagtttcaat gctgacgccc cacttctcta actggcacaa cttttccagc cgttccgccg
    13441 ccatataagt atgcgccacg ccgcttacgc aggcggttac tgccaccaga tatgccattt
    13501 taacctccca cggtaacctg aaatccggcc cgttctgcca tttcacgcat cgttgccaca
    13561 tcggctgacg acggcgcagc aacctctttc atcgaccatg ttttccccag caggcggtat
    13621 ttcggctcgc cgtactgatg aaacggtaac agatggatct gcttgatatt cagcgggatc
    13681 agcacgtcca gcgcctgctg catattctcc cggctgagcg tgaaaccagg gatcagcggt
    13741 aaacgcggga tcacgttgac accctcactc accagcaaac gcagattctc cagcacgcgt
    13801 tgcaggttca tcttcaccac atcccgcgcc tgagccgcat ccataatttt taaatcgaac
    13861 aacacttcat cgcacaattt cgccagcggt aacagcttgc tggctggcgc gtctccggca
    13921 gtttcgatgg cgcatgacac accccatagc cgcagtcgct gtaaaaaacg ggtcgcaaac
    13981 tccgcctgca ttaacacttc gccgccagaa agcgtgacgc cgccgccgga cgtgcgaaag
    14041 aaaatgtcat ctttcatcac ttcccgttcc agcgcgtcaa ggctgatatc gcggccaatc
    14101 cgttcaaatg ccccggaggg gcattcatcc gcatcacgca aacatttcgc gcagtgcaga
    14161 catttcgcct ctctgcgcac cgtctggatt ttgccggaga tcgactccgg attagcacac
    14221 catgggcaaa gatgcggaca gcctttaaaa aagaccaccg tacgaatgcc ctcgccgtca
    14281 ttcagtgaat aacgctgaat gttgaaaatg cgcgccacat catcgcggcg cgtttccaca
    14341 acgttacagc tgatgcgctg tccggcggat gatgtcatcc tggatctcct tcgacagttc
    14401 gacaaagaag gcgctgtatc cggcaacgcg caccaccagc ccggcataat cttgtgggcg
    14461 ctgttgcgct tcccgtaacg tgtcggcgtt caccacgtta aactgaatat gctgcaactt
    14521 aagctgggta aacgcccgta agaagtcggc cagtttgcgt aatcccgctt caccttcgag
    14581 ggtcgccgga gtgaatttca cgttcagcaa tgtaccgtta gaaagcagtg tgttatcgag
    14641 cttactgact gatttcagta ccgccgttgg tccttgtgcg tcctgaccca gcatgggtga
    14701 caagccaccg tctgccagtt gctctccggc aaagcgaccg tctggcgtcg cgccaaccac
    14761 cgctcccaac gggacatgag cagaaacggt atacgatccc ggcgtgaagt agccgccgcg
    14821 cgggttctgg tatttttcca cttctttgca gtagtggcgt aacagttcgg cgctaatgtt
    14881 atccacctcg tcgatatcgt taccgtattt ctcgaagcgg ttaattaagc gagcgcggac
    14941 tttttcgcct tctggcgtgg cgaagttggc ttttaatacc gacagcaatt cgtcaaaact
    15001 taaacgctgt tgatcaaaaa tcatcccttt caacgcatgg agagaatcgc tcaggttggc
    15061 gataccgatc ccctgtacgc cggagaagtt ataacgcgcg ccgccatcgg taatatcgcg
    15121 acctttttcc agacaatcgc tgataaaaga cgagagtagc ggtacaggtg cccagtcgcg
    15181 atggccgata tcacaaatat tgctgccctc aaccatcagg gtgatgtagt ggctgatctt
    15241 ggcgcggatc tgttccagta aaccttcata agtcagcgca gcgttgcctt cattttcatg
    15301 caggcagatt tccatcactt tcagcaggtt aaacatcgcg atgtcatgca agccgtaggt
    15361 tctgccggga atagataatt ccacacagcc cactacggaa tagtcgcgcg catcttccag
    15421 caaaacgcca cggttgagga acgctggcac taccacttca tcgttaaaga tttgcggaat
    15481 accggtgccg aggcgaatgg tttctgcggt tttcatcagg aacggcgtgt cgatcaaggc
    15541 gttagtgcgc acgccgaggt tcggttgcgg taattgcacg ctttgataag cgtcaaggca
    15601 aaggaacgaa agcacgttca ccgcgctacg tccgttctcg gttaacccgc cgagcagtgc
    15661 ggtatagccg gtagggaaac cggcgaaata acgcgcgcta ctggtggagc gcaacagcac
    15721 gatgtcgttg catttcaccc ataaagattc gagcagttct ttcaggaatg ccggatcttc
    15781 gccctgggtt aatgatgtct gatagaacgg caacatatac tggtcgaagc gccccaacga
    15841 tagcgaactg gcgttggatt cgtattgcag aatgatgttc atgtaccaga ataactggca
    15901 cgcctgccag aacgtctgcg gcttatgttc ggcgttatgg cgggagatct ccgcaatagt
    15961 cagcaattct tcgcgacgcg ggccatcagt gcagcttgcc gccatcgttt ccgccagttc
    16021 ggcgtaacgc aaaatatgtt tctgcgaggc ttccagcagt aacagcgctg cctgataaaa
    16081 gtgattctcc ggctgttgct gacaatgttg ctgcatctgt gccaccagct cccccagccc
    16141 gtgattcagc aggcgcgggt aatcaataat aatgtgcccc tggcctttat ccgtctggtt
    16201 gatgctgaaa atctgcgtgc tggtcgcggc ttttacttca tccgtcatct gcccgttgat
    16261 gaaatctttc atcgaacgtt tttcccagta cgggaacaac tcttcgcggt agatacgttt
    16321 atcttcttcg ctgatagcaa agcggtcctg cggacgcgtc gggaattgat ccagttcttt
    16381 cagcagccag taagggtcca tttccggcga cataatcccg gcgcgtggtt ttacggtgcg
    16441 gttaccggca atcagttctt catcacgaat cgaaatttca acgtgttcaa ggatatacgc
    16501 tgttgctttc gcccgacgca ttatcaccgg ctccccttcg gtttgccgat ggctggcggt
    16561 ataaagcaac gcccgctcca gcgagatttc acgggtattg gcaaacagtg cagttttgag
    16621 gcgagagata cgattcgtca tgaggaactc ctgtgggaaa gcgaacccgc ccttgcgggc
    16681 gggataagaa cttaagcggt ttgtgccagg tgagcttcaa ttttgctcat aatggcgtca
    16741 gcacgcttta ccgcgtcgct gatgttgaca cgcacgatag tcttgccagc aaaacgctct
    16801 tcaaatttga tgccgatatc tttggtcaaa atcaccatat cggcgcttgc cacgtcttcc
    16861 gcagtcagtt cattttccag accaatcgac ccctgggttt ctacttttac ttcccagcct
    16921 ttcgctttcg cggcgctttc cagcgcctct gccgccatat aagtatgggc aacacctgaa
    16981 ggacatgcgg ttactgcgat aattttcgtc atggctcgtt cctcaattaa ttaatttcaa
    17041 aatccagatc caggtcgtct tccttctctt cagttgaaga cccattttta cgcgccagac
    17101 ttttcagcac gttcacgcag actgccgtca caaccgcccc gacagccact gccgcgatgt
    17161 aacccaactt accttcaacc accggcagca caatcagacc accccagcct gcatagcact
    17221 gcgcaccgac cagcgccgca gttaccgcac cacaaactga accgaccatg atggaaggaa
    17281 tgacacgcag cggatcggca gcggcgaaag gaatcgcccc ttcagtaacg ccaacacagc
    17341 ccatcaccag tgccgccttg ccggtttcgc gctcttctgc ggagaaattt ttacgaccaa
    17401 tcagcgtcgc cagccccatc cccagcggtg gaacacaaat cccaacagcg gcaatagcca
    17461 ccacggtata aacaccctga gcaacgcaaa tcagcatgaa ggcataggcc actttgttaa
    17521 ccgggccgcc catatcgaac gccagcatca gacccatgat caccgccagc ataacaatgc
    17581 tgccctgctg catcccctga agccactggg tcaggctgtt ggtcaacgcc cccaccggct
    17641 cgcccagccc ccacatcatg acgccagcgg taatcagtgt gccgacgatt ggaatgatga
    17701 agattggcat taccgagcgc agaactttat gcactggaat tttcttcagg taatgcacca
    17761 cgatgccgcc gataatcccg gcgatcagcg caccaaagaa gcccgcgcca aagctgttac
    17821 caacccaggc accgatagcg catggagcca gcgcagaacg ttctgcaatg gaataaccga
    17881 tgtaagcggc gaggaaaggc accatcagcg tcaaacctgc aacgccgata tcaaacagtt
    17941 ttttcagatt cggatcggct acggcatccg gcactgcgcc tttgccatac aacatgacgg
    18001 aaaccgccag caaaataccg cccgatacca cgaagggaat catgtgtgaa acgcccgtca
    18061 ttaaatgctg acgggtattt ttcaggatct gcaccaactc attcataagc tgctcccggg
    18121 cttgcgaaag cccatgtcca tatttttgat ggaagaaaca ataggcaatc gcaggcggag
    18181 caaacagtgg ataaaaaggc catttactgg acttttgtaa tatcagtaca aaaatgcgat
    18241 ccgcctcata acttgcgata atccggaagt acgccgcaaa acggcgtctt gtgagacgcg
    18301 tcgcaaattg acggttacat tacatttgtc cagcttttgg cagatttgtc acatggcagg
    18361 ccgttgccgt gcgctcttat cctgtaaaca gaaaaccgta ccgggagaaa ggcaatggcc
    18421 ctgattgtgg aatttatttg tgagctacct aacggcgtcc atgcgcgtcc ggcaagccac
    18481 gttgaaacgc tgtgtaatac tttttcatca caaattgagt ggcataacct gcgcactgac
    18541 cgcaagggca acgccaaaag cgcccttgcg ctgattggca ccgatacgct ggtgggcgat
    18601 aactgccagt tactgatttc cggggccgac gaacaggaag cgcaccagcg tttaagccaa
    18661 tggctgcgcg atgaattccc ccactgcgac gcaccgctgg cggaagtaaa atctgacgaa
    18721 ctggaaccac tgccggtttc actgaccaat ctgaatccgc aaattatccg cgctcgcacc
    18781 gtgtgcagcg gtagcgcagg cggcattctg acgccgatct cttctttaga tctcaatgcg
    18841 ctgggtaatc ttcccgcagc caaaggcgtt gacgccgaac aatccgcact ggaaaacggt
    18901 ctgacgctgg tactgaaaaa catagagttt cgtctgctgg atagcgacgg tgctaccagc
    18961 gcgattctgg aagcgcaccg atccctggct ggcgatactt ccctgcgcga acatttactg
    19021 gcaggtgtca gcgccggatt aagctgcgcc gaagcgattg ttgccagtgc gaatcacttt
    19081 tgcgaagagt tcgcccgttc cagcagcagt tacctgcaag aacgtgccct ggacgtacgc
    19141 gacgtctgct tccagttact ccagcaaatc tacggtgagc aacgcttccc ggcaccgggc
    19201 aaactgacgc agcccgccat ttgtatggct gatgaactga cccccagcca gttcctcgaa
    19261 ctggataaaa atcatctcaa aggtctgtta ctgaaaagtg gcggcaccac atcacatacg
    19321 gtgatccttg cccgttcgtt caacattccg acgctggtag gtgtggatat tgatgccctt
    19381 actccgtggc agcatcagac gatttatatc gacggcaacg caggggcgat tgtggttgag
    19441 ccaggggaat ccgtggcccg ttattatcag caagaagccc gcgtacagga cgctctgcgt
    19501 gagcaacagc gtgtctggct gacccagcaa gcgcgtaccg ctgacggtat ccgcattgaa
    19561 attgccgcta acatcgctca ctccgtggaa gcgcaggccg cattcggcaa tggtgcggaa
    19621 ggcgttggtt tgttccgcac tgaaatgctc tatatggatc gcaccagtgc accgggtgaa
    19681 agcgagctgt acaacatctt ttgtcaggcg ctggagtctg ccaacggacg cagcattatt
    19741 gtgcgcacta tggacattgg tggtgacaaa cccgttgatt atctgaacat tcccgcagaa
    19801 gctaacccgt tcctcggtta tcgcgcggtg cgtatttatg aagaatacgc gtcgttgttt
    19861 accacacaac tacgatcgat cctgcgcgcc tctgctcacg gcagcctgaa aatcatgatc
    19921 ccgatgatct cctcaatgga agagatctta tgggtgaaag aaaaactggc ggaagccaaa
    19981 cagcaactgc gtaacgaaca cattccgttt gatgagaaga tccagctcgg catcatgctg
    20041 gaagtgccgt cggtgatgtt catcatcgat caatgctgcg aagagattga tttctttagt
    20101 attggtagta atgacctgac gcaatatcta ctggcagtgg atcgcgataa cgctaaggtg
    20161 actcgtcact acaacagcct gaatccggcc ttcttgcggg cgctcgatta cgccgtgcag
    20221 gcggtgcatc gccagggcaa atggattggt ctgtgcggtg aactgggagc gaaaggttcc
    20281 gtgctgccgt tgctggtcgg tttagggctg gatgaactca gcatgagcgc accatcaatt
    20341 ccggcggcga aagcgcggat ggcgcaactt gatagccgtg agtgccgcca gttgctcaac
    20401 caggcaatgg cctgccgtac ttcgctggaa gtggaacacc tgctggcgca attccgcatg
    20461 acccaacagg acgcaccgct ggtcaccgcc gagtgcatca cactggaaag cgactggcgc
    20521 agcaaagaag aagtgctcaa aggcatgacc gataacctgc tgctggcggg ccgctgccgc
    20581 tatccgcgta aactggaagc cgacttgtgg gcgcgcgagg ccgttttctc taccggactg
    20641 ggctttagtt tcgccattcc ccacagtaaa tcggaacaca ttgagcaatc caccatcagc
    20701 gtagcgcgtc tgcaagcgcc agtgcgctgg ggcgatgatg aagcgcaatt catcattatg
    20761 ttaaccctga acaaacacgc cgcgggcgat caacatatgc gcattttctc gcgcctcgct
    20821 cgtcgcatca tgcacgaaga attccgtaat gcgctggtta acgccgcctc tgccgacgct
    20881 atcgccagcc tgctgcaaca tgaactggaa ctgtaaaagg aaacatcatg gaactgtatc
    20941 tggacaccgc taacgtcgca gaagtcgaac gtctggcacg catattcccg attgccgggg
    21001 tgacaactaa cccgagcatt atcgctgcca gcaaggagtc catctgggaa gtgctgccgc
    21061 gcctgcaaaa agcgatcggt gatgagggca ttctgtttgc tcagaccatg agccgcgacg
    21121 cgcagggtat ggtgaaagaa gcgaaacgcc tgcgcgacgc tattccgggc attgtggtga
    21181 aaattccggt aacctctgaa ggtctggcag caattaaaat gctgaagaaa gaaggcatta
    21241 ctacgctggg aaccgcagtg tacagcgccg cgcaaggatt actggcggcg ctggctggag
    21301 ccaaatacgt tgctccatac gttaaccgcg tagatgccca gggcggtgac ggcattcgta
    21361 ctgtacagga gttgcaagcg ttactggaaa tgcatgcgcc agaaagcatg gtgctggctg
    21421 ccagctttaa aacaccacgt caggcgctgg attgtttgct ggcaggatgt gaatccatca
    21481 cactgccctt agatgtagcg caacaaatgc ttaacacccc tgcggtagag tcagctatag
    21541 agaagttcga gcacgactgg aatgccgcat ttggcactac tcatctctaa aggagtaatt
    21601 atggaccgca ttattcaatc accaggtaaa tacatccagg gcgcagatgt aattaatcgt
    21661 ctgggcgagt acctgaagcc actggcggaa cgctggttag tggtgggtga caaatttgtt
    21721 ttaggttttg ctcaatccac tgtcgagaaa agctttaaag atgctggact ggtagtagaa
    21781 attgcgccgt ttggcggtga atgttcgcaa aatgagatcg accgtctgcg tggcatcgcg
    21841 gagactgcgc agtgtggcgc aattctcggt attggtggcg gaaaaaccct cgatactgcc
    21901 aaagcactgg cacatttcat gggtgttccg gtagcgatcg caccgactat cgcttctacc
    21961 gacgcaccgt gcagcgcatt gtctgttatc tacaccgatg agggtgagtt tgaccgctat
    22021 ctgctgttgc caaataaccc gaatatggtc attgtcgaca ccaaaatcgt cgctggcgcg
    22081 cccgcgcgtc tgttagcggc gggtattggc gatgcgctgg caacctggtt tgaagcgcgt
    22141 gcctgttccc gtagcggcgc gaccaccatg gcgggtggca agtgcactca ggcagcgctg
    22201 gcactggctg aactgtgcta caacaccctg ctggaagaag gcgaaaaagc gatgcttgcc
    22261 gccgaacagc atgtagtgac tccggcgctg gagcgcgtga ttgaagcgaa cacctatttg
    22321 agtggcgttg gttttgaaag cggcgggctg gcggcggcac acgcggtaca taacggcctg
    22381 accgctatcc cggacgcgca tcactattat catggtgaaa aagtggcatt cggtacgctg
    22441 acgcagctgg ttctggaaaa cgcgccggtg gaggaaatcg aaaccgtagc tgcgcttagc
    22501 catgcggtag gtttgccaat aactctcgct caactggata ttaaagaaga tgtcccggca
    22561 aaaatgcgaa ttgtggcaga agcggcatgt gcagaaggtg aaaccatcca caacatgcct
    22621 ggcggcgcga cgccagatca ggtttacgcc gcactgctgg tagccgacca gtatggtcag
    22681 cgtttcctgc aagagtggga ataatctact ccaaactccc ggcttgtccg ggagtttgaa
    22741 cgcaaaattg cctgatgcgc tacgcttatc aggcctacgc aatctctgca atatagtaaa
    22801 tttacgtact tttgtagacc ggataaggcg ttcacgccgc atccggcacg ctgtgccagt
    22861 aatctgaaac ttccacgttg ttcgggtgtt tttttatccg cttctggaca ttttctccac
    22921 agaacaatcg ttagcccgga aggtcgaatc tgtgactctt attttcacgg acgaaacaga
    22981 tgaaagcttc actggcgtta ttcagtcttc tgacggtatt taccagttac tccttaaaat
    23041 ctcccgccgt tccaccaacc gtggtacaaa tccaggccaa caccaatctt gccatcgcag
    23101 acggcgccag acagcaaatc ggcagcacgc tattttacga tccggcgtat gtgcagctta
    23161 cctatcctgg cggtgatgtc ccgcaagaac gcggcgtatg ttccgatgtg gtgatccgtg
    23221 cattgcgcag ccagaaggtc gatttgcaga aactggtgca cgaagatatg gcgaagaatt
    23281 ttgctgcgta cccgcaaaaa tggcagttaa agcgcccgga cagcaacatc gatcaccgtc
    23341 gggtgcctaa tctggaaacc tggtttaccc gccacgataa aacacgcccc accagcaaga
    23401 accccagtga ctatcaagcg ggcgatattg tctcctggcg attagataac gggctggcac
    23461 atattggggt ggtgtcagat ggcttcgccc gcgacggtac gccgctggtg atacataaca
    23521 ttggcgcagg cgcgcaggaa gaagatgtac tgtttagctg gcggatggtg gggcactatc
    23581 ggtattttgc taaataagag atctccccac atgaagaaaa aattcagatc ctttttacac
    23641 tgacggcttc ttttttctta cggctcacca gcgccagtgc cagtacaatc agcacaatac
    23701 cgctaccttc aactgccccc ggattctcac cgagcagcca ccaggaaaag agtacgccgc
    23761 aaacgggaac ggccagtgtg cttaagctgg caatactggc aggcaagttt ttcaatacaa
    23821 acaaccataa gctccacgcc agcgctgtcg ccagaatcgc actgtaggcc agcgcccaga
    23881 acacggtggg ttgccagtca atttcacgtt gcggcaccag taaagcgacc acgctcatca
    23941 ccagcgccgc atacagcatc tgccaggatg ttagcgacaa taaatccacg cgcggatggc
    24001 gggcatacag acgtttagca acaatcgcgc tcgcccccca actcacaccg gagaggattg
    24061 ccagcatggc acttttcatc gaagagaaat cgagttgcca cggctgcaac accaaaaata
    24121 agccgaaagc ggcaatcagt atcgcgaaat attgcccacg tcgcaggcgt tcaccgagaa
    24181 acaacgcggc gaaaatcacc acccagaacg gcatggtata gctcaggatt gccaccttcc
    24241 ccgctccgcc gctgaccagc gcccactgtg ccaggccaac catcccgcag gtttgtaaca
    24301 gggcaatggc taaggtgtat ttaaacggcg tcgggcgcat tccgcgacca cgtaataaaa
    24361 gaacgatgaa taaaacgaga gcgccgaaaa tgcagcgtaa ggcggtgaag tcgaaggcac
    24421 cgatgtagct ggtgacttgc ttcatgaaaa tccagctata actccagata agtgtgagca
    24481 caaccaggcc actgattgcc agtgggttgc tctttcctgc ggcagacatg agagatccag
    24541 tgtgtagttt tcctgtggac actatacgcc ggtaaagaaa cttcagcgac tgcatgaaag
    24601 gcagtcgctg aagaaggtca gattacagca ggtcgaaacg gtcgaggttc atcactttca
    24661 cccacgctgc cacgaagtct ttaacaaact tctcgtgggc atcgctgctg gcgtagactt
    24721 ccgccaccgc acgcaggaca gagttagaac caaagaccag atccgcacgg ctggctgtgt
    24781 atttcacttc gccagtttcg cggtcacggc cttcgaacag ttctttcgat tcgtcggtcg
    24841 ctttccactc gtaacgcata tccagcaagt tcacgaagaa gtcattgctc aatacaccaa
    24901 cgcggtcagt gaagacgccg tttttgctgc catcgaagtt ggcacccagt acgcgcatcc
    24961 cgcccaccag cgcagtcatt tccggcgcgg tcagcgtcag ttgctgtgct ttatcaatca
    25021 acagtgactc ggtggtggaa acgtccagac gagcgcgata gttacggaaa ccgtcagcaa
    25081 ttggttccag cagttcgaac atctcaatgt cagtctgatc ctgacgcgca tcaacgcgac
    25141 ccggcgcaaa cggtacatga atgctcaaac ctgcggcgct tgcggctttc tcaacgccaa
    25201 ccacacctgc cagcacgatg atatccgcca gcgaagcttt gccagactct ttctgaattt
    25261 tctccagaac tggcagagca cgaacggctg cggcgttcac atcccagtca cgctgcggca
    25321 ttaatgccag acgcgcaccg ttggcaccac cacgtttgtc gccaccacgg aaggtagaag
    25381 cagacgccca ggccaccgat accagctcac taacagacag accagaatcc gcaatcgcga
    25441 atttcagatc gataatgtcc tgctcggtcg ggttgtagat cggctgcggc agcggatctt
    25501 gccagatcag atcttctttc ggtacttccg gcccgatgta acgagatttc ggccccatat
    25561 ccctgtgcgt cagtttgaac caggcacgag caaaggcttc gttgaacgcc tgcggatcgt
    25621 tgaggaaacg acgagagatc ttctcgaact caggatcaaa acgcagcgtc aggtcggtca
    25681 ccagcatcgt cggtttacgt ttcttcgacg gatcaaacgg atccgggata atttccggtg
    25741 cgtctaccgc ttcaaactgg attgcgccag ccgggctgcg ggtctgtacc cactcatact
    25801 tgaacaggtt ctcgaagaaa tagttgctcc actgggtcgg cgtctgggtc cagaccactt
    25861 ccagaccaga ggtaatggca tctgcgccaa cgccgctgcc gtaagtgctc gcccagccta
    25921 aaccttgttc ttcaatcggt gcagcttctg gatcaggacc tacatttgat gtcggaccgg
    25981 caccgtgggt tttacccagc gtatgaccac ccgcaatcag cgccacggtt tcttcgtcat
    26041 tcatgcccat gttgccgaag gtcgcgcgga tagctgctgc tgccgaaagt ggttcgccgc
    26101 tgtgatccgg gccttccggg ttaacgtaaa tcaggcccat ctcggttgca cccagcggtg
    26161 ctttcgccag cgcttccgga tgacggtgag tcagccaggc tttttcatca ccccagttaa
    26221 catccagatc cggttcccag acgtcttcac gaccggcacc aaaaccgaag gtacggaagc
    26281 cggagttttc cagcgccacg ttacccgcga ggataaacag gtcggcccag gagattttct
    26341 gaccatattt ctgtttgatt ggccacaaca ggcgacgcgc tttatcgagg cttacgttat
    26401 ccggccagga gttcagcggt gcaaagcgtt gctgaccacg acccgcgccg ccgcgaccgt
    26461 cgattgaacg gtaagtaccc gcgccgtgcc aggccatacg aataaacaga ccagcgtagc
    26521 tgccccagtc ggcaggccac cacggctgag attctgtcag cagggctttc agatcttttt
    26581 tcaggccgta gtaatctaat ttgctgaatt ctttgcggta gtcaaagtcc tcacccagcg
    26641 ggttagaacg attagaatgt tggtttaaca ggtcaacacg gagttgattt ggccaccagt
    26701 cgcgcgtggt tgtgccccca cctgcgctct ggtcgtgacc gccctgatgg aacgggcatt
    26761 tgccggtggc tgtcgtgtta tggatatcgt ctgacgtgct catcaatgtg ctcccctcta
    26821 cagtgttacc gttacgatac acagcgttag agagaagtta taattgaatt aatccacgga
    26881 tgcgatagtt gagatcttac atattgttgg ttaaagagat gtagatcaaa ttgatcgtaa
    26941 ttaagacttt ttgattatgt ccgatttagg acaaatgctt tataaaaaag ggttttagat
    27001 ttgtatcctt caagtaatga gggagaaaac aaggctgata accttatttt cccgccctca
    27061 tttcgaggca gcattttgtg ctctgtttaa aatttgtgaa cactgtgtga ttttcacaaa
    27121 aggcacaata cttataaacc aggtcgaact cccagtgtat ggcaaatcgc ataactcatt
    27181 tcagcgcggt taagcgtata gaagtggaaa tctttcactc cttcacggct taaaatcttc
    27241 accatatcca tggcgatatt cgcgcccacc agcttgcggg tttcagcatc gtcatccagg
    27301 ccgtcgaaca tttgtgccat ccacgccgga atacgcacgt tggtcatgtc ggcaaatttc
    27361 ttcgcctgtt taaagttcga aaccggcaaa attcccggaa tgatttccac atcaatgcct
    27421 gccgagacgc agcgatcgcg aaaacgcagg tagctttcga catcgaagaa gaactgagta
    27481 atggcgcggt tggctccggc atccactttt cgtctcaggt tgagtaaatc ggcctgggca
    27541 cttttcgctt ctggatgtac ttccggatac gccgccacgg agatatcgaa atctgccact
    27601 tcttttaaca gcgtcaccag gtcagaagca tacatttctg gcttaccact tcccggcggc
    27661 aggtcgccac gcagcgccac gatatggcga ataccgttat tccagtagtc gcgtgcaatg
    27721 atccgcagct cggcaggcgt cgcatcaatg caggtaagat gcggtgccgc ttccaggccg
    27781 gtgcgatctt taatgccttt aataatgctg tgcgtacggt cgcgctcgcc ggagtttgcg
    27841 ccataggtca ccgatacaaa cttcggtttc aggctgctaa ggcgatcgat ggagttccac
    27901 agggtctgct ccatttcact ggtacgcggc gggaaaaatt cgaacgaaac gttaatctgc
    27961 ccctggactt ctgccagact ctgattcagg gcatcccgct ggctggcgtg aaaaaagctc
    28021 ataccttacc tcatcaatcg cttatcgtta tatgttgtgt tgtgcacatc tatccgttta
    28081 gacgtccaga tgtaaagatg aaggaaaagc cgaagggcgt caaccgaaaa ataaccaatg
    28141 atggtgagga aaaatcaggg aagatgaaaa aaactcatct taattagagg cgataaaaga
    28201 tttctctata gcgcaatcca cctcgcacgt tttgactcat attctgacaa cacagcgaca
    28261 cctgggctaa ttcgaaaaac aacgtcctgc caccggatgg tgatgttaag gcatctgatt
    28321 cggcctgcgc cctcgcgtag gccgaataca ggatctgcgc aatcaacggg taacaaacag
    28381 ttgagtcaat tcagtgcgca cttttatttg atatccttca cgcgcatacc gttgagctgt
    28441 tcatccgtaa tggtgttgcc cgctttgaag taatcaacca ccgcgtgata aacgtaataa
    28501 ccgcccgttg tgttacgcgc tttcccttcg gtaaaggcgg taaaaccatc tccaccatca
    28561 gcaaggaaac tctgagtagc aatgtgataa accgtcgcat cttcaatggg tttgccattc
    28621 aaagtcagtg tgattacccg ctgaccaacc ggcctgttgc tgtcgtactt catttccagg
    28681 cctttcgata cctgtaaaac gccattgctt aaacttgcgc cgtgttccat cagactgcgt
    28741 aattgtttac ccatgagttc catcgtcacc agttcgttgg ggaacggaaa cgtactgatg
    28801 acgccgccca tcgtgatcgc ccctgcgggg atctcattgc ggataccacc agagtttgtt
    28861 aacgccagtt gggtgttttt acccgccgct accaataaag cgtcagccgc caggttcccg
    28921 agggaagccg attcaccata ggcacgtttt aattcaaccg gcgattgcgc caccgtttgt
    28981 tgcaccactt catcaagctt tttattccag ccgtcgatca cctgtttcgt ttgcggatcg
    29041 ggcttccact cgtcagcgta aatggtttta agctcgaagt ttttcaccgt aaaattatgc
    29101 ggcttctctt tgtagtcgag aaccagtttg cccacatcaa tcccgccgct gtcagtggag
    29161 aggatgagcg tattgccgac tttaatcggt tccggcgtac ccacatgtgc atgtccggtg
    29221 atcaaaatat ccagcccttt cacctgactt gccgtctgaa tatctttatc caacgcgcga
    29281 cgcacatctg tgcctcccat actggactgg cgggctggaa caccttcgtg gatcagggcg
    29341 acggtcaaat caaccttgcc tttgagttca tcgatataac gttgtagcca tttaatttca
    29401 tcgcgcgctt caatacccac gcgcgtggca gcagataccg tatcattaaa ggcaaatact
    29461 ccgtgcaaac caataacgcc tattttcaca ccgtcttttt cgatgatggt atagggctta
    29521 tcccagaatg atttactgct gttctgataa aaaatattgc cctgcacaat agggaatttt
    29581 gcctggctca actgtaataa tgtgttgtcc cagccgtggt caaattcatg gttgcctatt
    29641 gtgacggcat caaacggcat agtattcata atatcgataa tagccttacc tttggtcagg
    29701 ctgctgatat atggcccggt aaaatagtcg cccgcatcaa aaaaccatgt cgctttattt
    29761 tttgcttttt cttgcttaac cagcgtagtg atatttgccc agccgccaat atcccgttta
    29821 ccgtcagcga tccacggcac tttataaggc tcgacatgtg catggaggtc gttggtataa
    29881 atgatggtga catctttagc gcaagcccag aatggcagtg ttaatgcgat acccgcagca
    29941 agtattttaa ttttcataaa cagtcccttt cagtgagata aaggattgct acattacgtt
    30001 ctgaaagact tatttatgtg agagtaatca catccgcagg ggatagttgc cggacaaaat
    30061 caacgacctt gtgaaatcgt tggtgatata tgtcgactct gtttacgatt aatgcctgta
    30121 agtcgtttgg ttgccgtaat ttagggcagc caacatcgac agattatagc tggcccgact
    30181 atcgactggg ttatccggca ctgcactgtc gggcatgtgg cagttacccg ccgttgtttg
    30241 acgagcaaca atttcgtgac tggttgacag ttcacttatc tacttttgca acagagaaag
    30301 gccatttttg cccggtatgt tatggcacag agacgatttg ttatggtcac aatccacagg
    30361 gttcgcaacg cattcaatgc cgtaactgca aaaaagtatg gacacccaaa caatatcaga
    30421 aagaaataac gactcccgaa ataatcgaaa cggttgcttt gctcgtgcca tttcagggag
    30481 tcagcagcgg gcagaaactg tatgttttaa tcagttttga tgctcttcgc ggtaatattc
    30541 ttcatctttc tactaattac acgcagcatc aggctggaga aagtctgcat tatcgataca
    30601 gaggaaatgc agaaccagag ttacacgaca ataatattgt acaacgcgtt gatatgcgcg
    30661 aagcacaatt tctacgccgc agtcagtttg atgaaattca gtatggcagc gcagcgctca
    30721 agcgcaatgc caaaggcgct attctgcgtc cggttatcac tgcacacggg catttcagag
    30781 tactgaatat tttattccct acagtaaaaa cacatgtaat ttcacacgag tgttttttaa
    30841 gaggtgccat tattacggcc tgggctgatc tgtttcgcca acagcaaggt gaaatttggt
    30901 ttattgaaga ggaaatagct gacgataccg ataatatgcc ctggcgtttt cagggaaaaa
    30961 cttatcacgg ctggtggaaa aatcagtggc aactctgggt tcagggaaaa aatcgtaaaa
    31021 tggtatgtgc attaacgggc ggaaagagta gcaaagcaga aatgctctct ttagcaacca
    31081 gcagacattt tatcgactgg ctacataaac aagcagtatt tactcacagc gccccgcttt
    31141 ccgcagggcg cgttacgcaa atactgcttt ctctggctca ggattacaac aactgcgcca
    31201 gtcggttaat atccgactga atcgccccgg cggtgacgtc gcgccctgca cctggcccgc
    31261 ggatcaccag cgggttgtcg cgataccagc ggctttcgat ggcaaagacg ttatcgcatg
    31321 gcagtagtga tgccagcgga tggtcttcac gcaccgcttc cacgcccaca cgcgctttgc
    31381 cattggcatc gaaacgcgcc acgtagcgca gcaccagccc catttcgcgg gccgcttcca
    31441 gtcgttgcac catctgctcg ttaagttcat cgccattttc aaagaaatgg tcgatgctgc
    31501 cgccttcgca atgggcaggc accagtgatt caacacgtac ctggtccggt tcaatgttgt
    31561 aacccgcttc acgcgccaga atcaccagct tgcgcattac gtctttgccg gaaaggtcat
    31621 cacgcgggtc aggttcggtt aagccttgct gccacgcctg atccaccagt tcggtaaacg
    31681 gcacgctacc gtcgaattgc aggaacagcc aggagagcgt gccggagaag atcccactga
    31741 tcgacaaaat ggtatcgccg ctgtcgatca gatcgcgcac ggtatggttg atcggcaaac
    31801 ccgcaccgac ggtggcgttg tacagccagt gacgcccggt tttttcgaag gcgtcgtgga
    31861 tctggcgata tttattgctg tcgcttgctc ctgccagttt gttggcactg atgacgtgga
    31921 aaccgtggct ggcgaaatca agatactggt cagcgagctg ctggctggcg gtaacgtcca
    31981 gcaccactaa atcatcatac ggatgggcgc gcatccacag gaacagcgac tcttcatcct
    32041 gctcgaccgc ttcatcgttg aagaaggcta acgcgcggct ggcgtccaga ccgtcatagc
    32101 tcaacaggct acggcggctg tccaccacgc ctgccagcac aaattcaaag ccggtacgtg
    32161 ccgaaagcgt actctgctca cgggcgaaca gttccagcca gcgggaaccg atattgccct
    32221 tgccgaacaa taccaggccg atgcgttttt ccgcgcggaa gacggactga tgcagcccct
    32281 gaatcaggct ttcggtcggg ccggtgcgca gtactgccac caggctgatg ccgtcatcgg
    32341 actgccaggt aaattcgacc ggctggcctt tcagttgctg ccagaagcgg tggcaatgca
    32401 gcgggttacg ggtgacgccc gccccaacca tcgccaccag cgccagcccc tgacgcaggc
    32461 gcagttcgcc aggtaatccc gcttcgtcga ggattttcag cgcactgtcg gccacttctg
    32521 aggtgtagca aaattgcagc aactggcgat cgttatgcac gccaaccgcc agtggacgta
    32581 cctgagcacg tttcaggatc tggtcgatct ctttatgcgc cagtttgaaa tcctggctgg
    32641 cgggcacctg aaactcaatc aagcagacat catcatggct ggtgacaata cgcgcaccag
    32701 taccggaggc cagcacgcgt tcaatgcgcg tggaaccttg atccggcgtg tagctacagc
    32761 gcagttgcag gtcgatttcg ctgccagaaa cgggctgtaa agtacgggca tgaagaacgg
    32821 gagccgccag acgcgccagt tcgctggctt catccagacg cagcaacggc agcaggcagg
    32881 catctttcac tttacgcggg tcggcgctat ataccccggc gacgtcgctc cagatggtta
    32941 cgcgagaaac acccgccagc gcaccgattt gtgtcgcgga atagtcggaa ccgttacgcc
    33001 ccagcagcac cgtttcaccg gcgttgttac ggctgataaa cccggtcacc accagacgtt
    33061 tgcccggatg ttgtaccagt agctgttgca gcaacgggta agaaagccct tcatcaacct
    33121 gcggttgcgc agcgcgttca gcgcgtaaaa actcgcgggc atcaagccag gccgatggca
    33181 gcccttgttg attaagcacc gcagacatca ggcgcgccga ccacacttca ccgtggccca
    33241 ccacttccgc atacaccgca tcgttaatac cgctgtcgag caacgccgcc aggcgctcaa
    33301 gatcgctgac aaaagcgcta atgaggttat cggcttcttc ggcgggtagc aggccgctaa
    33361 tcagatcgca ctgataacga cgtaatgttt gttgaacctg atgcgcagag agacgatcgg
    33421 tctggcttag tttcaaccag ttaatcaact ggttagtggt gctaccggcg gcggaaacca
    33481 ccatcatatc gtcaggctga gagtactccg ccataatgcc cgcgacacgc aaataacact
    33541 tcacatcagc cagactactg ccaccaaatt tatgcagttg acgacctttc gcccctgcct
    33601 gcgcaatcac actcattttt accccttgtt tgcagcccgg aagccatttt ccaggtcggc
    33661 aattaaatct tcgccatctt caataccggt ggagatacgc agcagcgtct cggagatccc
    33721 ggcggcagca cgcgcttctg gtgccatgcc tgcatgtgtc atggttgcgg cgtgagagat
    33781 taaactttcc actcccccta atgattccgc cagcgtaaac aacgacagcc cgcccaggaa
    33841 acgacgcagc gtctgctcat cgccatccag ttcaaaactc aacattgcgc caaagccttt
    33901 ttgctggcgc gcggcaattt catgcccctg attttccggc agcgacgggt gatacagttt
    33961 cttcaccaac ggctgggttt gcagatattt cacaatcgcc tgcgcgttgc gctgcgccag
    34021 ctccatacgc ggcaccagcg ttcgcaaccc gcgcagcagc agatagctgt caaacgcgcc
    34081 gcccgtcacg ccaatattgt ttgcccacca ggcaagttca gtgacaacgt ccgggtcttt
    34141 agcaatcact acgcctgcca ccacgtcaga gtgaccgttc agatatttcg tgcatgaatg
    34201 caacaccaga tcggcaccta atgccagtgg attttgtaat gccgggctta agaaggtgtt
    34261 atccaccacg ctcaccgccc cgacttccct tgccagatgg caaattttcg caatatccac
    34321 gacgcgtaac aatggattac ttgggctttc taccagtacc agtttgggtt tttctgccag
    34381 cgctgcccgt aatgcctgtt catcgctttg atcaacaaac aacacgcgat agcaaccgcg
    34441 tttcgccagg ctgtcgaaca ggcgatagct accgccgtag cagtcgtgcg gcgcaaccag
    34501 cagatcgcca ggtttcaaaa agacggtcgt taccaggtga atcgcggaca tgccggtatt
    34561 agtaagtacg gcaccggcac cgccttccag ttctgccagc gcacgctgaa ccacatcgcg
    34621 cgttgggttg ccgcgacgcg agtaatcatg cgcacgtggt tcattaaatc cggtaaagtt
    34681 ataggtactg gaaagatgga tgggagggac aacgcaacca tactgttcgt cgtcatttaa
    34741 cccgctacgc actgcgatgg tggcctgttt acgcgtcatg tgatgaagtt ccctgggctt
    34801 tgtcggtgaa atgtcaggca ccagagtaaa cattgtgtta atggacgtca atacatctgg
    34861 acatctaaac ttctttgcgt atagattgag caaatcccaa atagccgtta aaattatatg
    34921 cattatcacg ccgacaggtg cattacacga tgtcacggta acgcctgtac ggtaaactat
    34981 gcgggtttac ggtcagtacc cacattaact gtgtggtctg gtctcaattt attgacgaag
    35041 aggattaagt atctcatggc tgaatggagc ggcgaatata tcagcccata cgctgagcac
    35101 ggcaagaaga gtgaacaagt caaaaagatt acggtttcca ttcctcttaa ggtgttaaaa
    35161 atcctcaccg atgaacgcac gcgtcgtcag gtgaacaacc tgcgtcacgc taccaacagc
    35221 gagctgctgt gcgaagcgtt tctgcatgcc tttaccgggc aacctttgcc ggatgatgcc
    35281 gatctgcgta aagagcgcag cgacgaaatt ccggaggcgg caaaagagat catgcgtgag
    35341 atggggatta acccggagac gtgggaatac taaagcggaa aagagcggcg cggagttaac
    35401 cagccgcttt tttcatacat ggacgtttaa cgatgaaaat caggctactg atccccggcc
    35461 tgctggtttc tgtgcctgca tttgcctggc aaccacaaac cggcgacatc atctttcaga
    35521 tctctcgctc atcgcaaagt aaagcgatcc aactggcgac ccattccgat tacagccaca
    35581 ccggtatgct ggtgatacgc aacaaaaagc cctacgtctt tgaagccgtc ggcccggtaa
    35641 aatatacccc gctgaaacag tggatcgccc acggtgaaga tagcaagtac atcgtgcgtc
    35701 gcgttaaagg cgagctaaat gccgaacaac agcaaaaact ggcgcaaacg gcaaaacgtt
    35761 atctcggtaa accgtatgac tccagcttct cgtggagcga cgatcgccag tactgttcgg
    35821 aagtggtgtg gaaggtctac cagaatgcgc tgggaatgcg tgtgggcgag cagcagaagc
    35881 tgaaagagtt cgatcttagt aacccgctag ttcaggcaaa gctcaaagaa cgctacggca
    35941 aaaatattcc gcttgaggaa acggtagttt caccacaagc cgttttcgac gcgccacaac
    36001 tcaccacggt cgccaaagaa tggccgctgt tttcctggta atacgaccaa aattcaggca
    36061 caaaaaaagc gccgtgcggc gcttttttcg gaaatccggt cttatttgct gcccgggatg
    36121 ttgaaacgct tgttgaagcg gtcaacacgg ccaccggtag caacatcacg ctgtttgcca
    36181 gtgaagaacg ggtggcactt gctgcacacg tcgaggttca ggtcatgacc aacggtggag
    36241 cggattttca ttacgttacc gcaagagcag ctagcagtaa tttcttcgta tttcgggtga
    36301 atatcttttt tcatgggaaa acctcggttt aaggccgcgt cgctcttcca gccctaacgc
    36361 cagacaccac gcgatgttaa aagtatagct tcaatacgat catttcgtac gaaggcgcga
    36421 aatcatacag aaattaacca gcgtatgcaa actgatccgc actcttctac ggcaatgtgt
    36481 atactaaccc accgaatttc aagtcaggat gatgctatgc ccgttgccca cgttgccttg
    36541 cccgttccgc ttcctcgtac ctttgactat ctgctgccag aaggcatgac ggttaaagcc
    36601 gggagtcgcg tgcgcgtgcc gtttggcaaa caacaggagc gcatcggggt tgtggtgtca
    36661 gtgagcgatg tcagtgagct gccgcttaac gagctgaaag cggtagttga agtgctggac
    36721 gttgagccgg tatttactca ctccgtctgg cgattactgc tctgggcggc agattactat
    36781 catcatccga ttggcgatgt gctgtttcat gccttgccga ttttactgcg ccaggggcgg
    36841 cctgcggcaa acgcgcctat gtggtactgg tttgccactg aacaaggtca ggcggtggat
    36901 ctgaacagcc tgaaacgttc gccaaagcaa caacaggcgc tggcagcgtt acggcaaggc
    36961 aaaatctggc gcgatcaggt tgccacgctc gaatttaatg atgccgcgtt gcaggcactg
    37021 cgcaaaaaag gtctgtgtga tttagcaagt gaaacaccag agtttagcga ctggcgaacg
    37081 aactatgccg tttctggtga gcggttgcgg ttgaataccg aacaggccac cgccgttggc
    37141 gcaattcata gcgcggcaga tactttttct gcctggctgc tggcgggcgt taccggttcc
    37201 ggtaaaacgg aggtttatct cagtgtactg gaaaacgtgc tcgctcaggg caaacaggcg
    37261 ctggtgatgg tgccggaaat cggcctgaca ccgcaaacta tcgcccgttt tcgtgaacgt
    37321 tttaatgccc cggtggaagt tctgcattcc ggcctgaacg acagcgagcg tctttcggcg
    37381 tggttgaaag cgaaaaatgg cgaggcggcg attgtcatcg gcacccgctc cgcgctgttt
    37441 acgccgttta aaaatctcgg cgtgattgtt attgatgaag agcacgacag ttcctacaaa
    37501 cagcaggaag gctggcgcta tcatgcccgc gacctggcgg tgtatcgcgc gcatagcgag
    37561 caaatcccaa ttattcttgg ctccgcaacg cccgcactgg aaacgttatg caacgtgcag
    37621 cagaaaaaat accgcctgct gcgcctgacc cgtcgggcgg gcaatgcgcg cccggcaatt
    37681 caacatgtgc tggatttaaa aggtcagaag gtgcaggcag gtctggctcc ggcgttgatc
    37741 acccgtatgc gccagcattt acaggccgac aaccaggtta tcctctttct taaccgccgg
    37801 ggttttgcgc ctgcgctact gtgccacgac tgtggctgga ttgccgaatg cccgcgttgc
    37861 gatcactact acacgctgca tcaggcacaa cagcatttgc gctgtcacca ctgtgacagc
    37921 caacgcccgg tgccgcgcca gtgcccttcc tgcggttcca cacacctggt acccgtgggg
    37981 ctgggcaccg aacagcttga acagacgctc gcgccgctgt tccccggcgt gcccatttct
    38041 cgtatcgacc gcgataccac cagccgcaaa ggggcgctgg aacagcaact ggcggaagtg
    38101 catcgcggcg gcgcgaggat cttgattggc acgcaaatgc tggcgaaagg tcaccacttt
    38161 ccggatgtga cgctggtagc gttactggat gtggacggcg cgctgttttc tgccgatttt
    38221 cgctcggcag agcgtttcgc tcagctttac acccaggtcg ctggtcgtgc cgggcgtgcg
    38281 ggtaaacagg gcgaagtggt gctgcaaacg caccatccgg aacatcctct gttgcaaacg
    38341 ttgctctata aaggctacga cgactttgcc gaacaggcgc tggctgagcg acggatgatg
    38401 cagctgccgc catggaccag ccatgtgatt gtgcgtgcgg aagatcataa caatcagcac
    38461 gcgccgctgt tcctgcaaca gttgcgtaat ctgatcctcg ccagcccgct tgcagacgac
    38521 aaactgtggg ttctcggtcc ggttccggca ctggccccta agcgtggtgg ccgctggcgc
    38581 tggcaaattt tgttgcagca cccttcccgc gtgcgattac agcacatcat caatggtacg
    38641 ctggcgctta ttaatacaat accggattcc cgtaaagtga aatgggtgct ggatgtcgat
    38701 cccatcgagg gctaaaccgc tcacgatgcg aggcggatcg aaaaattcaa tattcatcac
    38761 acttttcatg aaaattctgt aaccgttttc acgcgctatc tgctaaaaat gttgccgatg
    38821 tgaagtaaac atggatgtag tacgcctgac gtgccaggcg aggagtgagt gtgaaagcga
    38881 agaagcagga aactgccgcg accatgaaag acgttgccct caaggcaaaa gtctctacag
    38941 cgactgtctc ccgagcatta atgaatcccg ataaagtctc ccaggccacc cgtaatcggg
    39001 ttgaaaaagc ggcccgggaa gtgggttatt taccgcagcc tatggggcgc aacgtcaagc
    39061 gtaatgaatc ccgcaccatt ctggtgattg tcccggatat ctgcgaccct ttctttagcg
    39121 aaattattcg cggtatcgaa gttacggcgg caaatcacgg atatctggtg ctgattggcg
    39181 actgtgcgca tcaaaatcag caggaaaaaa cctttatcga tttgatcatc accaagcaaa
    39241 ttgatggcat gttgttgctg ggttcaaggc tgccgtttga tgccagcatt gaggaacagc
    39301 gtaatctgcc gccgatggtg atggcgaacg aatttgcacc ggaactggag ctgcctaccg
    39361 ttcatatcga caatctgacc gccgcatttg atgcagtaaa ttatttatat gagcaagggc
    39421 ataaacggat tggctgtata gccggtcccg aagagatgcc gctgtgtcac taccgcctgc
    39481 aaggctatgt tcaggcgctg cgtcgctgcg gcattatggt tgatccgcaa tacatcgccc
    39541 gtggcgactt caccttcgaa gccggaagca gagcaatgca acagctgctt gatcttccac
    39601 aaccgcctac tgctgtcttc tgccatagcg atgtgatggc gctcggcgca ctttctcagg
    39661 caaaacgtca ggggctgaaa gtcccggaag acctttccat aatcggtttt gataacatcg
    39721 acctgacgca attttgtgat ccgccgctga caaccatcgc gcagccgcgt tacgaaatcg
    39781 gtcgggaagc tatgctgtta ttgcttgatc aaatgcaggg gcaacacgtt ggcagtggct
    39841 ctcgtttaat ggactgcgaa cttatcatcc ggggatcaac acgcgcgtta ccttaaagta
    39901 aacctttaag actgccgtga ctggtcaaag gcccgccgct taagtaacat ggcgggctga
    39961 cgaacgaata aatacagcga aacgatagtg gcacaacgag attatgtacg ccgcagccaa
    40021 ccggcacctt cgcggcgaaa aaagagcacc tcacggaaaa agcaacgaaa tctgcctgcg
    40081 gtttctcccg ctatggtcgc tattgctgcc gccgttcttg tgacctttat cggtggtctg
    40141 tacttcatta cgcatcacaa gaaagaagag tccgagacgc tgcaaagcca gaaagtgacc
    40201 ggaaacggac taccaccaaa accagaagaa cgctggcgct acattaaaga gctggaaagt
    40261 cgccagccgg gtgtgcgtgc gcccacagaa ccttctgccg gtggtgaagt gaaaacgccg
    40321 gagcaactga caccagaaca acgccagctt cttgaacaaa tgcaggccga tatgcgccag
    40381 cagccaacgc agctggttga agttccgtgg aatgagcaga cgccggaaca gcgtcagcaa
    40441 acgctacagc gccagcgtca ggcgcagcaa ttagcggagc agcaacgcct ggctcagcag
    40501 tcgcgtacga ctgaacaaag ctggcagcag cagacgcgta cgtcgcaagc cgcgccggta
    40561 caggcgcaac cgcgccagtc taaaccggct tctactcagc agccgtacca ggatctgctg
    40621 caaacccctg cgcacacgac cgcgcagtcg aagccgcagc aagctgcgcc ggttgctcgt
    40681 gccgctgacg cgccaaaacc gacggcggag aaaaaagacg aacgccgctg gatggtgcag
    40741 tgcggttcgt tcagaggcgc ggaacaggca gagacggtac gtgctcagct ggcgttcgaa
    40801 ggctttgact caaaaattac caccaacaat ggctggaatc gtgtggtgat tggcccggtg
    40861 aaaggcaaag agaacgcaga cagcaccctc aatcgcttga agatggcggg tcatacaaac
    40921 tgcattcggc tcgccgccgg gggttgaaac cctcaaaatc ccccccatct ataattgcat
    40981 tatgccccgt acttttgtac ggggtttgta ctctgtattc gtaaccaagg ggtcagctcg
    41041 tgacaactat agtaagcgta cgccgtaacg gccatgtggt catcgctggt gatggtcagg
    41101 ccacgttggg caataccgta atgaaaggca acgtgaaaaa ggtccgccgt ctgtacaacg
    41161 acaaagtcat cgcgggcttt gcgggcggta ctgcggatgc ttttacgctg ttcgaactgt
    41221 ttgaacgtaa actggaaatg catcagggcc atctggtcaa agccgccgtt gagctggcga
    41281 aagactggcg taccgatcgc atgctgcgca aacttgaagc actgctggca gtcgcggatg
    41341 aaactgcatc gcttatcatc accggtaacg gtgacgtggt gcagccagaa aacgatctta
    41401 ttgctatcgg ctccggcggc ccttacgccc aggctgcggc gcgcgcgctg ttagaaaaca
    41461 ctgaacttag cgcccgtgaa attgctgaaa aggcgttgga tattgcaggc gacatttgca
    41521 tctataccaa ccatttccac accatcgaag aattaagcta caaagcgtaa ggatctccca
    41581 tgtctgaaat gaccccacgc gaaatcgtca gcgaactgga taagcacatc atcggccagg
    41641 acaacgccaa gcgttccgtg gcgattgctc tgcgtaaccg ctggcgtcgc atgcagctca
    41701 acgaagagct gcgccatgaa gtgaccccga aaaatatcct gatgatcggc ccgaccggtg
    41761 tcggtaaaac tgaaatcgcc cgtcgtctgg ctaagctggc gaatgcgccg ttcatcaaag
    41821 ttgaagcgac caaattcacc gaagtgggct atgtcggtaa ggaagtggat tctattattc
    41881 gcgatctgac cgatgccgcc gtgaaaatgg tacgcgtcca ggctatcgag aaaaaccgtt
    41941 atcgcgctga agaactggca gaagaacgta ttctcgacgt actgatccca ccggctaaaa
    42001 ataactgggg acagaccgaa cagcagcagg agccgtccgc tgctcgtcag gcattccgca
    42061 aaaaactgcg tgaaggccag cttgatgaca aagaaattga gatcgatctt gccgcagcac
    42121 cgatgggcgt tgaaattatg gctcctccgg gcatggaaga gatgaccagc cagctgcagt
    42181 ccatgttcca gaacctgggc ggtcagaagc aaaaggcgcg taagctgaaa atcaaagacg
    42241 ccatgaagct gctgattgaa gaagaagcgg cgaaactggt gaacccggaa gagctgaagc
    42301 aagatgctat cgacgctgtt gagcagcacg ggatcgtgtt tatcgacgaa atcgacaaaa
    42361 tctgtaagcg cggcgagtct tccggtccgg atgtttctcg tgaaggcgtt cagcgtgacc
    42421 tgctgccgct ggtagaaggt tgcactgttt ccaccaaaca cgggatggtc aaaactgacc
    42481 acattctgtt tatcgcttct ggcgcgttcc agattgcgaa accgtctgac ctgatcccgg
    42541 aactgcaagg tcgtctgcca atccgcgttg agctgcaggc actgaccacc agcgactttg
    42601 agcgtatttt gaccgagccg aatgcctcta tcaccgtgca gtacaaagca ctgatggcaa
    42661 ctgagggcgt aaatatcgag tttaccgact ccggtattaa gcgcatcgcg gaagcggcat
    42721 ggcaggtgaa cgaatctacc gaaaacatcg gtgctcgtcg tttacatacc gttctggagc
    42781 gtttaatgga agagatttcc tacgacgcca gcgatttaag cggtcaaact atcactattg
    42841 acgcagatta tgtgagcaaa catctggatg cgttggtggc agatgaagat ctgagccgtt
    42901 ttatcctata atcgcgttca atcattttca tcattgtttg atggggctga aaggccccat
    42961 ttttattggc gcgtattatg actgaacaac aaattagccg aactcaggcg tggctggaaa
    43021 gtttacgacc taaaaccctc cccctcgcct ttgctgcaat tatcgtcggg acggcgctgg
    43081 catggtggca aggtcacttc gatccactgg tcgccctgct ggcattgatt accgccgggc
    43141 tattacagat cctttctaac ctcgccaatg attacggcga tgcggtaaaa ggcagcgata
    43201 aacctgaccg cattgggccg ctacgcggca tgcaaaaagg ggtcattacc cagcaagaga
    43261 tgaaacgggc gctcattatt accgtcgtgc tcatctgtct ctccgggctg gcactggttg
    43321 cagtggcgtg ccatacgctg gccgattttg tcggtttcct gattcttggc gggttgtcga
    43381 tcattgccgc tatcacctac accgtgggca atcgtcctta tggttatatc ggtttgggtg
    43441 atatttccgt actggttttc tttggctggt tgagcgtcat ggggagctgg tatttacagg
    43501 ctcatacatt gattccggca ctgatccttc cggcaaccgc atgcggcctg ctggcaacgg
    43561 cagtactgaa cattaataac ctgcgtgata tcaatagcga ccgcgaaaac ggcaaaaaca
    43621 cgctggtggt gcgcttaggt gcagtaaacg cgcgtcgtta tcatgcctgc ctgctgatgg
    43681 gctcactggt gtgtctagcg ctgtttaatc tcttttcgct gcatagcctg tggggctggc
    43741 tgttcctgct ggcggcaccg ttgctggtga agcaagctcg ttatgtgatg cgcgaaatgg
    43801 acccggtggc gatgcgacca atgctggaac gcactgtcaa aggagcgtta ctgactaacc
    43861 tgctgtttgt tttagggata ttcctaagcc agtgggcagc ataactgaca aatatcaatt
    43921 aacaattgat gattttgcca acagcccaca tagcgcgata tactgaaaat tctcgcagca
    43981 actgaatgtt aagcctatga aatacgatac ttccgagctt tgtgacatct atcaagaaga
    44041 tgttaacgtc gtggaaccgc tgttctccaa ctttggcgga cgggcgtcgt ttggcggaca
    44101 aataatcacg gtaaaatgtt tcgaggacaa cgggttgctg tacgatctgc tcgaacagaa
    44161 tggccgtggt cgtgttcttg tcgtcgatgg cggaggttct gttcgccgcg cactggtcga
    44221 tgctgaactg gcgcgtctgg cagtacaaaa tgaatgggaa ggcctggtca tttacggcgc
    44281 ggtgcgtcag gtagatgacc tggaagagtt ggatatcggc atccaggcga tggcggcaat
    44341 tccggttggt gccgctggcg aaggcattgg cgaaagcgat gtccgcgtca attttggcgg
    44401 tgtcaccttc ttctccggcg accatcttta tgccgacaat accgggatta ttctttcaga
    44461 agatccgctg gatattgaat gataaaaaag gcaccgcaag gtgccttttt tctgcgttac
    44521 ctgttggcct acacagtaaa gaaattacgc gaaagatgaa gtgtaatcag acctcttcca
    44581 tgcgacccag cagggcctgc agacgttcct gccagccgtt ctgctgttct ttcagatggt
    44641 tgttctcacg ctccagctct tcgcgctgat gctgggcatt ttgaacttcc tgcgacagtg
    44701 agttgttttt ttctttcagc tcttcgattt ccatctgcaa cagagtgatg gtatcaatcg
    44761 cctgctgtac ttttgcttcc agtttctcaa acacttctaa tgacattgtc atacctctcc
    44821 tgaattgcaa ggcgttgatg gataaaaatc ctcgtcccga ttaccggtga cgccttaata
    44881 aatacgagcg cactttagtt agctccgatt gtatgaagcc gcgccatcgc tgtccagcgg
    44941 cacgccttgc agattacggt ttgccacact tttcatcctt ctcctggtga cataatccac
    45001 atcaatcgaa aatgttaata aatttgttgc gcgaatgatc taacaaacat gcatcatgta
    45061 caatcagatg gaataaatgg cgcgataacg ctcattttat gacggagcac acacatttta
    45121 agttcgatat ttctcgtttt tgctcgttaa cgataagttt acagcatgcc tacaagcatc
    45181 gtggaggtcc gtgactttca cgcatacaac aaacattaac tcttcaggat ccgattatga
    45241 gtcaaacatc aaccttgaaa ggccagtgca ttgctgaatt cctcggtacc gggttgttga
    45301 tttttttcgg tgtgggttgc gttgcagcac taaaagtcgc tggtgcgtct tttggtcagt
    45361 gggaaatcag tgtcatttgg ggactggggg tggcaatggc catctacctg accgcagggg
    45421 tttccggtgc gcatcttaat cccgctgtta ccattgcatt gtggctgttt gcctgtttcg
    45481 acaagcgcaa agttattcct tttatcgttt cacaagttgc cggcgctttc tgtgctgcgg
    45541 ctttagttta cgggctttac tacaatttat ttttcgactt cgagcagact catcacattg
    45601 ttcgcggcag cgttgaaagt gttgatctgg ctggcacttt ctctacttac cctaatcctc
    45661 atatcaattt tgtgcaggct ttcgcagttg agatggtgat taccgctatt ctgatggggc
    45721 tgatcctggc gttaacggac gatggcaacg gtgtaccacg cggccctttg gctcccttgc
    45781 tgattggtct actgattgcg gtcattggcg catctatggg cccattgacg ggctttgcca
    45841 tgaacccagc gcgtgacttc ggtccgaaag tctttgcctg gctggcgggc tggggcaatg
    45901 tcgcctttac cggcggcaga gacattcctt acttcctggt gccgcttttt ggccctatcg
    45961 ttggcgcgat tgtaggtgca tttgcctacc gcaaactgat tggtcgccat ttgccttgcg
    46021 atatctgtgt tgtggaagaa aaggagacca caactccttc agaacaaaaa gcttcgctgt
    46081 aatatgacta cgggacaatt aaacatgact gaaaaaaaat atatcgttgc gctcgaccag
    46141 ggcaccacca gctcccgcgc ggtcgtaatg gatcacgatg ccaatatcat tagcgtgtcg
    46201 cagcgcgaat ttgagcaaat ctacccaaaa ccaggctggg tagaacacga cccaatggaa
    46261 atctgggcca cccaaagctc cacgctggta gaagtgctgg cgaaagctga tatcagttcc
    46321 gatcaaattg cagctatcgg tattacgaac cagcgtgaaa ccactattgt ctgggaaaaa
    46381 gaaaccggca aacctatcta taacgccatt gtctggcagt gccgtcgtac cgccgagatc
    46441 tgcgaacatc tcaaacgcga tggcatggaa gagtacattc gtaacaacac cggtctggtg
    46501 attgacccgt acttctctgg caccaaagtg aagtggatcc tcgaccatgt ggaaggctct
    46561 cgcgagcgtg cgcgtcgtgg tgaattgctg tttggtacgg ttgatacgtg gcttatctgg
    46621 aaaatgactc agggccgtgt ccatgtgacc gattacacca acgcctctcg taccatgttg
    46681 tttaacatcc atactctgga ctgggacgac aaaatgctgg aggtgctgga tattccacgc
    46741 gagatgctgc cagaagtgcg tcgttcttcc gaagtatacg gtcagactaa cattggcggc
    46801 aaaggcggca cgcgtattcc aatctccggg atcgccggtg accagcaggc ggcgctgttt
    46861 ggtcagttgt gcgtgaaaga aggaatggcg aagaacacct acggtaccgg ctgctttatg
    46921 ctgatgaaca ctggcgagaa agcggtgaaa tcagaaaacg gcctgctgac caccatcgcc
    46981 tgcggcccga ctggcgaagt aaactatgcg ctggaaggtg cggtgtttat ggcgggcgcg
    47041 tccattcagt ggctgcgcga tgagatgaag ttgattaacg acgcctacga ttccgaatat
    47101 tttgccacca aagtgcaaaa caccaatggt gtgtatgtgg ttccggcctt taccgggctg
    47161 ggtgcgccat actgggatcc gtatgcacgc ggggcgattt tcggtctgac tcgtggggtg
    47221 aacgctaacc acattatacg cgcgacgctg gagtctattg cttatcagac gcgtgacgtg
    47281 ctggaagcaa tgcaggccga ctccggtatt cgtctgcacg cgctgcgcgt ggacggcggt
    47341 gcggtggcga acaatttcct gatgcagttc cagtccgata ttctcggtac gcgcgttgag
    47401 cgcccggaag tgcgcgaagt caccgctttg ggtgcggcct atcttgctgg tctggcggtt
    47461 ggcttctggc agaatcttga cgagctgcaa gagaaagcgg tgattgaacg cgagttccgt
    47521 ccaggcatcg aaaccactga gcgtaattac cgttacgcag gctggaaaaa agcggtcaaa
    47581 cgcgcgatgg catgggaaga acacgacgag taataatgat tgcctgatgc gacgcttgcg
    47641 cgtcttatca ggcctacgag tcggatacac atccggcatc acgcagactc tgaaaccgtg
    47701 cgggggcaac cccgcacaca tcaataatcc cgcccttccc ctgtgctaca cttcgcgcca
    47761 ttccttactg cttagagttt gctatgagac gagaacttgc catcgaattt tcccgcgtca
    47821 ccgaatcagc ggcgctggct ggctacaaat ggttaggacg cggcgataaa aacaccgcgg
    47881 acggcgcggc ggtaaacgcc atgcgtatta tgctcaacca ggtcaacatt gacggcacca
    47941 tcgtcattgg tgaaggtgaa atcgacgaag caccgatgct ctacattggt gaaaaagtcg
    48001 gtactggtcg cggcgacgcg gtagatattg ctgttgatcc gattgaaggc acgcgcatga
    48061 cggcgatggg ccaggctaac gcgctggcgg tgctggcagt aggcgataaa ggctgtttcc
    48121 tcaacgcgcc agatatgtat atggagaagc tgatcgtcgg accgggagcc aaaggcacca
    48181 ttgatctgaa cctgccgctg gcggataacc tgcgcaatgt tgcggcggcg ctcggcaaac
    48241 cgttgagcga actgacggta acgattctgg caaaaccgcg ccacgatgcc gttatcgctg
    48301 aaatgcaaca actcggcgta cgcgtatttg ctattccgga cggcgacgtt gcagcctcaa
    48361 ttctcacctg tatgccggac agtgaagtcg atgtgctgta cggcattggc ggcgcgccgg
    48421 aaggcgtggt ttctgcggcg gtgatccgcg cattagatgg cgacatgaat ggtcgtctgc
    48481 tggcacgtca tgacgtcaaa ggcgacaacg aagagaatcg tcgcattggc gagcaggagc
    48541 tggcacgctg caaagcgatg ggcatcgaag ccggtaaagt attgcgtttg ggcgatatgg
    48601 cgcgcagcga caacgtcatc ttctctgcca ccggtattac caaaggcgat ctgctggaag
    48661 gcattagccg caaaggcaat atcgccacca ccgaaacgct gctgatccgt ggtaaatcac
    48721 gcaccattcg tcgcattcag tccatccact atctggatcg taaagacccg gaaatgcagg
    48781 tgcacattct ctgagtgatt tgatcgattg agccttccag tccttcggga ctggaatttt
    48841 tttgttcgga gaacgaagat aaggcaagtc aatcaaaaca ggagaaaaac atggctgatt
    48901 gggtaacagg caaagtcact aaagtgcaga actggaccga cgccctgttt agtctcaccg
    48961 ttcacgctcc cgtgcttccg tttaccgccg ggcaattcac caaacttggc cttgaaattg
    49021 aaggcgaacg cgttcagcgt gcctactctt acgttaactc gcccgacaat cccgatctgg
    49081 agttttacct ggtcaccgtc cccgatggca aattaagccc gcgactggcg gcgctaaaac
    49141 cgggtgatga agtgcaagtg gttagtgagg cggcaggctt ctttgtgctg gatgaagtcc
    49201 ctgactgcga aacactgtgg atgctggcga ctggtacggc gattggccct tatttatcga
    49261 ttctgcaatt gggcaaagat ttagaacgct tcaaaaacat ggtgctggtt cacgccgcac
    49321 gatatgccgc cgacttaagc tatctacctc tgatgcagga actggaaaaa cgctacgagg
    49381 ggaaactgcg cattcagacg gtggtcagtc gggaaacggc tgcgggttcg ctcactgggc
    49441 ggataccggc gttaattgaa agtggtgaac tggaaagcgc ggttggcctg ccgatgaata
    49501 aagaaaccag ccatgtgatg ctgtgcggca atccacagat ggtgcgcgat acacaacagt
    49561 tgctgaaaga gacccggcag atgacgaaac atttacgtcg ccgaccgggc catatgacag
    49621 cggagcatta ctggtaagcg gttacttgtc gataaacggc acgatcaaga gatccgcact
    49681 caacttattg atcatcccgc gatatgccgg catcaaacgg ttgataaatg agtggtgatg
    49741 accacagaca aggaggtcgc actgctcttt ttgcataatt tccagcagtg tttccggcat
    49801 ttctccgcgt tcaatacgca gttttgtctt cggccattga atatttttcg tcagtttata
    49861 cagcttgtta tccgacttat tcttcaacaa ttgaagaata tcttctgttg cagggaagta
    49921 gatacccgga tacaactcgc ttaagccatc atcaatatga attaacgtca ggtgagcgtc
    49981 attatgtctg gcgagctcca gggctttatt caccagtaag gcatcttctt cattcccgga
    50041 aattgccacg ccaatgtgtt tataagccat gtttaactcc ttctaaagca actccatcaa
    50101 gctaacgaac gcagtgataa ctcaaaaata atcatctcgg cctggcatga gaaggtgaag
    50161 gccgcatcaa gctcaacttg cccttccaga tctttaatct tataggccac gctggcccct
    50221 tcatctgcag aggatgcagc ggcggcaagc tctttcagtt tggtcataaa ggactctgct
    50281 tcttcgcggg tggcaaaaaa gcgcgaaaac ttactggtac agttgtcgtt atcaatcacc
    50341 gtaccgatat caatcgcaca tcctttagta ctgcatttat ctacgacatc tttcataggg
    50401 cacctctgta tattcgcctc tctgtcgatt acgacttaag aataatgcgc cgttaaagga
    50461 agaacaaaca agtaatgatc ttatggatta ccattttttt tgatattgct taaggtgaag
    50521 agttcagaag gattttccgg gcattgtcac ttgcatcgtg gaaataacaa tcccggaaaa
    50581 aaatagcgat aaga
//
LOCUS       DAFGPF010000021        49701 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFGPF010000021 DAFGPF010000000
VERSION     DAFGPF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49701
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.021"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            93..725
                     /gene="comR"
                     /locus_tag="LSX49_001453"
     CDS             93..725
                     /gene="comR"
                     /locus_tag="LSX49_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HBL7167883.1"
                     /translation="MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDHYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIARTTLRLWPELLK"
     gene            complement(787..1326)
                     /locus_tag="LSX49_001454"
     CDS             complement(787..1326)
                     /locus_tag="LSX49_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HBL7167884.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKV"
     gene            complement(1553..2857)
                     /gene="ndh"
                     /locus_tag="LSX49_001455"
     CDS             complement(1553..2857)
                     /gene="ndh"
                     /locus_tag="LSX49_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HBL7167885.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
     gene            complement(3256..3798)
                     /locus_tag="LSX49_001456"
     CDS             complement(3256..3798)
                     /locus_tag="LSX49_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7167886.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            complement(3821..4846)
                     /gene="nagZ"
                     /locus_tag="LSX49_001457"
     CDS             complement(3821..4846)
                     /gene="nagZ"
                     /locus_tag="LSX49_001457"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HBL7167887.1"
                     /translation="MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRE
                     LVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISARLNQLHERW
                     QEEKAGH"
     gene            complement(4857..5681)
                     /gene="thiK"
                     /locus_tag="LSX49_001458"
     CDS             complement(4857..5681)
                     /gene="thiK"
                     /locus_tag="LSX49_001458"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HBL7167888.1"
                     /translation="MPFRSNNPLTRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRL
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTDQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            complement(5662..6303)
                     /gene="lpoB"
                     /locus_tag="LSX49_001459"
     CDS             complement(5662..6303)
                     /gene="lpoB"
                     /locus_tag="LSX49_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HBL7167889.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPTEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            complement(6317..6694)
                     /locus_tag="LSX49_001460"
     CDS             complement(6317..6694)
                     /locus_tag="LSX49_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HBL7167890.1"
                     /translation="MRKGCFGLVSLALLVLVGCRSHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            complement(6697..7056)
                     /gene="hinT"
                     /locus_tag="LSX49_001461"
     CDS             complement(6697..7056)
                     /gene="hinT"
                     /locus_tag="LSX49_001461"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HBL7167891.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            7390..9579
                     /gene="fhuE"
                     /locus_tag="LSX49_001462"
     CDS             7390..9579
                     /gene="fhuE"
                     /locus_tag="LSX49_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HBL7167892.1"
                     /translation="MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPATEETV
                     IVEGSATAPDDGENDYNVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDRSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTKWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRNLSITGTYQF"
     gene            complement(9639..11072)
                     /gene="ptsG"
                     /locus_tag="LSX49_001463"
     CDS             complement(9639..11072)
                     /gene="ptsG"
                     /locus_tag="LSX49_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HBL7167893.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLT
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(11367..12164)
                     /locus_tag="LSX49_001464"
     CDS             complement(11367..12164)
                     /locus_tag="LSX49_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL7167894.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            complement(12175..13179)
                     /gene="holB"
                     /locus_tag="LSX49_001465"
     CDS             complement(12175..13179)
                     /gene="holB"
                     /locus_tag="LSX49_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBL7167895.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNALGIDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYGVQSGDWYSLLAALNNEQAPARLHWLATLLMDALKRHYGAAHVTNVDVPGLVVE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            complement(13176..13817)
                     /locus_tag="LSX49_001466"
     CDS             complement(13176..13817)
                     /locus_tag="LSX49_001466"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBL7167896.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTNWVKELDA"
     gene            complement(13807..14829)
                     /gene="yceG"
                     /locus_tag="LSX49_001467"
     CDS             complement(13807..14829)
                     /gene="yceG"
                     /locus_tag="LSX49_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HBL7167897.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDQVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            complement(14832..15641)
                     /gene="pabC"
                     /locus_tag="LSX49_001468"
     CDS             complement(14832..15641)
                     /gene="pabC"
                     /locus_tag="LSX49_001468"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HBL7167898.1"
                     /translation="MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTAYPAHYDRLRNEGMTLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEEALQADEMVICNALMPVMPVRACGDVSFSSATLYEYLAPLCERPN"
     gene            complement(15761..17002)
                     /gene="fabF"
                     /locus_tag="LSX49_001469"
     CDS             complement(15761..17002)
                     /gene="fabF"
                     /locus_tag="LSX49_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBL7167899.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            complement(17090..17326)
                     /gene="acpP"
                     /locus_tag="LSX49_001470"
     CDS             complement(17090..17326)
                     /gene="acpP"
                     /locus_tag="LSX49_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL7167900.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            complement(17537..18271)
                     /gene="fabG"
                     /locus_tag="LSX49_001471"
     CDS             complement(17537..18271)
                     /gene="fabG"
                     /locus_tag="LSX49_001471"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HBL7167901.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            complement(18284..19213)
                     /gene="fabD"
                     /locus_tag="LSX49_001472"
     CDS             complement(18284..19213)
                     /gene="fabD"
                     /locus_tag="LSX49_001472"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL7167902.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            complement(19229..20182)
                     /gene="fabH"
                     /locus_tag="LSX49_001473"
     CDS             complement(19229..20182)
                     /gene="fabH"
                     /locus_tag="LSX49_001473"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HBL7167903.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLTANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            complement(20250..21320)
                     /gene="plsX"
                     /locus_tag="LSX49_001474"
     CDS             complement(20250..21320)
                     /gene="plsX"
                     /locus_tag="LSX49_001474"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBL7167904.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            complement(21401..21574)
                     /gene="rpmF"
                     /locus_tag="LSX49_001475"
     CDS             complement(21401..21574)
                     /gene="rpmF"
                     /locus_tag="LSX49_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL7167905.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            complement(21626..22147)
                     /gene="yceD"
                     /locus_tag="LSX49_001476"
     CDS             complement(21626..22147)
                     /gene="yceD"
                     /locus_tag="LSX49_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HBL7167906.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            22346..22930
                     /gene="yceF"
                     /locus_tag="LSX49_001477"
     CDS             22346..22930
                     /gene="yceF"
                     /locus_tag="LSX49_001477"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HBL7167907.1"
                     /translation="MPELILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            complement(23042..24001)
                     /gene="rluC"
                     /locus_tag="LSX49_001478"
     CDS             complement(23042..24001)
                     /gene="rluC"
                     /locus_tag="LSX49_001478"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HBL7167908.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDDGLKRCLQKLRNAR"
     gene            24574..27759
                     /gene="rne"
                     /locus_tag="LSX49_001479"
     CDS             24574..27759
                     /gene="rne"
                     /locus_tag="LSX49_001479"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HBL7167909.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKSAPATPAAPA
                     QPGLLSRFFGALKALFSGGEETKPSEQPTPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     PRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQTPRRERSRR
                     RNDDKRQAQQEVKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETVAAEPIVQEAAAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVQVQPMVTEVPVAAAAEPVVSAPVVEEVAEVVEAPVQVAEPQPEVVETTH
                     PEVIAAAVTEQPQVITESDVAVAQEVAEHAEPVVEPQEETADIEEVAETAEVVVAEPE
                     VVAQPAAPVVAEVTAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQR
                     PTFAFEGKGAAGGHTATHHASAAPARPQPVE"
     gene            complement(27954..28907)
                     /gene="flgL"
                     /locus_tag="LSX49_001480"
     CDS             complement(27954..28907)
                     /gene="flgL"
                     /locus_tag="LSX49_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBL7167910.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTESAPFSEADGKYEGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLNK"
     gene            complement(28919..30562)
                     /gene="flgK"
                     /locus_tag="LSX49_001481"
     CDS             complement(28919..30562)
                     /gene="flgK"
                     /locus_tag="LSX49_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBL7167911.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPA
                     VLQNTKNKGDVAIGATVTDTSAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASAEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSTTQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            complement(30628..31569)
                     /gene="flgJ"
                     /locus_tag="LSX49_001482"
     CDS             complement(30628..31569)
                     /gene="flgJ"
                     /locus_tag="LSX49_001482"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HBL7167912.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPIKFPLETVVRYQNQTLSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF"
     gene            complement(31569..32666)
                     /gene="flgI"
                     /locus_tag="LSX49_001483"
     CDS             complement(31569..32666)
                     /gene="flgI"
                     /locus_tag="LSX49_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HBL7167913.1"
                     /translation="MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            complement(32678..33376)
                     /gene="flgH"
                     /locus_tag="LSX49_001484"
     CDS             complement(32678..33376)
                     /gene="flgH"
                     /locus_tag="LSX49_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HBL7167914.1"
                     /translation="MQKNAAHTYAISSLLALSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            complement(33430..34212)
                     /gene="flgG"
                     /locus_tag="LSX49_001485"
     CDS             complement(33430..34212)
                     /gene="flgG"
                     /locus_tag="LSX49_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HBL7167915.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            complement(34384..35139)
                     /gene="flgF"
                     /locus_tag="LSX49_001486"
     CDS             complement(34384..35139)
                     /gene="flgF"
                     /locus_tag="LSX49_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HBL7167916.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLVVQTADGSEGYTRN
                     GSIQVDPTGQLTIQGHPVVGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAESQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            complement(35159..36364)
                     /gene="flgE"
                     /locus_tag="LSX49_001487"
     CDS             complement(35159..36364)
                     /gene="flgE"
                     /locus_tag="LSX49_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HBL7167917.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDSLPSVNAFDASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWDVYTLDSSDP
                     TGTANPATTLVFNANGVLTSDPTKDITTGAINGADPATFSLSFLNSMQQNTGANNIVA
                     TTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWSA
                     TQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQ
                     ILNTLVNLR"
     gene            complement(36389..37084)
                     /gene="flgD"
                     /locus_tag="LSX49_001488"
     CDS             complement(36389..37084)
                     /gene="flgD"
                     /locus_tag="LSX49_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HBL7167918.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSISGQIDNSQSLQASNLIGHGVMI
                     PGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNNGNTLDLGT
                     YGTTTLDEVRQII"
     gene            complement(37096..37500)
                     /gene="flgC"
                     /locus_tag="LSX49_001489"
     CDS             complement(37096..37500)
                     /gene="flgC"
                     /locus_tag="LSX49_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBL7167919.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            complement(37504..37920)
                     /gene="flgB"
                     /locus_tag="LSX49_001490"
     CDS             complement(37504..37920)
                     /gene="flgB"
                     /locus_tag="LSX49_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBL7167920.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPSAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            38075..38734
                     /gene="flgA"
                     /locus_tag="LSX49_001491"
     CDS             38075..38734
                     /gene="flgA"
                     /locus_tag="LSX49_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HBL7167921.1"
                     /translation="MLTIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVR
                     VSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIVRGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAVSLRDLSPDQPIQLTHFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMISGQVVSGVVDADGNILIN
                     L"
     gene            38810..39103
                     /gene="flgM"
                     /locus_tag="LSX49_001492"
     CDS             38810..39103
                     /gene="flgM"
                     /locus_tag="LSX49_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HBL7167922.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            39108..39524
                     /gene="flgN"
                     /locus_tag="LSX49_001493"
     CDS             39108..39524
                     /gene="flgN"
                     /locus_tag="LSX49_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HBL7167923.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEIAVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTPYRGSKKISI"
     gene            complement(39564..41099)
                     /gene="murJ"
                     /locus_tag="LSX49_001494"
     CDS             complement(39564..41099)
                     /gene="murJ"
                     /locus_tag="LSX49_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBL7167924.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGILQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(41209..42132)
                     /locus_tag="LSX49_001495"
     CDS             complement(41209..42132)
                     /locus_tag="LSX49_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL7167925.1"
                     /translation="MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALP
                     ICDSWRIPYADSLSSLAASCDAVFVHSSTASHFGVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATASSLRMDKHRTNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGNATLESGTLLTNESGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVDCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            complement(42134..42781)
                     /locus_tag="LSX49_001496"
     CDS             complement(42134..42781)
                     /locus_tag="LSX49_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HBL7167926.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRE
                     SRYMHLFSGEVENPPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            complement(42792..43376)
                     /gene="rimJ"
                     /locus_tag="LSX49_001497"
     CDS             complement(42792..43376)
                     /gene="rimJ"
                     /locus_tag="LSX49_001497"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HBL7167927.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALSAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            43612..44820
                     /gene="mdtH"
                     /locus_tag="LSX49_001498"
     CDS             43612..44820
                     /gene="mdtH"
                     /locus_tag="LSX49_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415583.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HBL7167928.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSY
                     MGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKR
                     AARRLLERDA"
     gene            44884..45531
                     /gene="grxB"
                     /locus_tag="LSX49_001499"
     CDS             44884..45531
                     /gene="grxB"
                     /locus_tag="LSX49_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HBL7167929.1"
                     /translation="MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            45664..46224
                     /locus_tag="LSX49_001500"
     CDS             45664..46224
                     /locus_tag="LSX49_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL7167930.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            46330..47373
                     /gene="pyrC"
                     /locus_tag="LSX49_001501"
     CDS             46330..47373
                     /gene="pyrC"
                     /locus_tag="LSX49_001501"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBL7167931.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVK"
     gene            47450..47695
                     /gene="dinI"
                     /locus_tag="LSX49_001502"
     CDS             47450..47695
                     /gene="dinI"
                     /locus_tag="LSX49_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HBL7167932.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
     gene            47984..48238
                     /gene="bssS"
                     /locus_tag="LSX49_001503"
     CDS             47984..48238
                     /gene="bssS"
                     /locus_tag="LSX49_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415578.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HBL7167933.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFQVNEYRRH"
     gene            48353..49471
                     /gene="solA"
                     /locus_tag="LSX49_001504"
     CDS             48353..49471
                     /gene="solA"
                     /locus_tag="LSX49_001504"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HBL7167934.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHH
                     GDTRLIRHAYGEGEKYVPLVLHAQMLWDELSRHNEDDPIFVRSGVINLGPADSAFLAN
                     VAHSADQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
                     EAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRK
                     VFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERV
                     PFAEVASDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITG
                     LSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            49519..49632
                     /locus_tag="LSX49_001505"
     CDS             49519..49632
                     /locus_tag="LSX49_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HBL7167935.1"
                     /translation="MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF"
BASE COUNT        12064 a        13358 c        12319 g        11960 t
ORIGIN      
        1 aagcgattat ttttatggtt tctggactgg tgaacggagg tgattatttt tataataacc
       61 tttcattcac agtcaccagg tacaacggca tcatggcaac tgactcaaca caatgtgtaa
      121 aaaaaagccg tggccgccca aaagtgttcg acagggatgc cgcgcttgat aaggccatga
      181 aattgttctg gcagcacggt tatgaagcga cttctcttgc ggacctcgtt gaagcgaccg
      241 gagctaaagc gcccacgcta tacgcggaat ttaccaacaa agaggggtta ttccgcgccg
      301 tactcgacca ctatatcgat cgttttgccg ccaagcatga agcacagctg ttttgtgaag
      361 agaaaagcgt ggagtctgcg ctggctgact attttgctgc catcgccaac tgctttacca
      421 gcaaagacac tccggctggc tgcttcatga tcaacaactg caccaccctc tccccggatt
      481 caggagatat cgccaatacg ctgaaatcac gccatgcgat gcaagagcgc actttgcagc
      541 agtttttatg tcaacgacaa gcgcgcgggg aaatcccgac ccactgtgac gtgacgcatc
      601 tggcagaatt ccttaattgt attattcagg ggatgtcgat cagcgcacgc gaaggtgcat
      661 cactggaaaa actgatgcag attgcccgaa cgactttgcg tttatggccg gaactgctga
      721 aataggtcgc aaaaaaagcc cctcagcctg agcgaatgag gggctaaatt gcagagtaca
      781 gccttgttat actttgttat tcaaaatcag ctgcccgttg ctatctagcg ggatctgcgt
      841 acccggatcg cggtccatgc ggattttgcc ctgctgatcg ccaatcttat aggtcacatc
      901 ataaccgagc attttttctg acttgtcata caccgtttta caacgctgtt gcgtagtcgt
      961 gtaagtatcg ctttcctgga gagagccctg gatctggtta cctgcatatc caccccccag
     1021 cgcccccaca acagtggcga catctttacc gcgaccacct ccaaactgat gcccaatcac
     1081 gccgccagca acagcgccga gcaccgaccc ggtaatgcga ttttcatcct gcaccggtcg
     1141 acgatgggtc actgtaacgt tgcgacactc ctgacgcggt gttttaaccg tttccttgat
     1201 tggggttgca gaaacaacct gagcgtattg cgggccacgt tcaaacacgt tcagactggc
     1261 cactgccgct acgcccagcg cagctgcgac accaatcccg atacccgcca acattgactt
     1321 attcacggga acacctcctt ctttgtagtt atgccaatca tgcaagcgaa ggagaaaagc
     1381 agctatcaga cagaagatga aaagcgcggg aatggctgga aatactcagg gattcggagg
     1441 agtctgaagg aatgcctgat gcgacgctta acgcgtctta tcaggcctac cgctcgtacc
     1501 atttgtccag ggcggataag gcgtttatgc cccatccgcc agtacaagtc gattaatgca
     1561 acttcaaacg tggacggata acgcggttaa tactccccac cagcatcatt aatccggttt
     1621 taaagtaacc atgcagcgca atctggtgca ttcggtacag cgagatgtat acaaagcgcg
     1681 caattcgtcc ttcaatcatc attgagccgc gcgtcaggtt acccatcagg ctaccgactg
     1741 tggaaaagtt cgacagcgat accagcgaac cgtgatcttt atactgataa tttttcagcg
     1801 gcttaccgtt catctgcgcc agaatgttgt tcattgcgca ggttgccatc tgatgtgcgg
     1861 cctgagcgcg cggcggaaca aagccccctt ccggacgcgg gcatgacgcg cagtcgccaa
     1921 tagcgtatat gtctggatcg cgagtggttt gcagcgtcgg ttccaccacc agctggttga
     1981 tacggttggt ttcaagacca ccgatatctt tcaggaagtc tggcgctttg atcccggctg
     2041 cccacaccat cagatcagcc tcaatatatt cgccatcttt agtgtgcagg ccgccttcat
     2101 cagcactggt gaccatggtt tgcgtcagca cgcgaacgcc aagtttcgtt aactcactat
     2161 gggccgcagc agagatacgt ggcggcaatg caggcaaaat acgttcgccc gcttctacca
     2221 gcgttacgtt cagggcttcg ttggtcagac ctttataacc gtaactgtgc agttgcttga
     2281 ccgcgttgtg caattcagcg gagagttcta cacccgtcgc gccgccgccg acaatcgcaa
     2341 tgtttacttt gccattcgcg cccaggttgg cggagtattt caggaacaga ttcagcatct
     2401 cctggtggaa gcgacgcgcc tggtgcgggt tatcgaggaa aatgcagttc tctttgacac
     2461 ctggtgtatt gaaatcgtta gaggtgctac ccagcgccat taccagggtg tcataggcga
     2521 ttttacgttc cggaaccagc agttcacctt tctcgtcgcg cagttctgca atagtgattg
     2581 ttttcgcttc acgatcaata tcaattacgg aacccagctg gaactggaaa ccatgattgc
     2641 gcgcatgggc cagatagctc aacgcatcga cgccttcatc aagcgagcca gtcgccactt
     2701 cgtgcagcag cggtttccac aagtggctgt ggttacgatc gaccagcgta attttggctt
     2761 ttttcttgcg tcccagctta tgccccagct gtgttgccat ttccagccca ccagcaccgc
     2821 cgccgacaat cacaattttt ttcaatggcg tagtcaacgt gaccccctta aatttattaa
     2881 ccaattgtta attaatggtt attaacatag ctcttaatta acaacaggtt atagcaatga
     2941 aaatgttctt cgctattgag aataacatga atggtgcatt ggtcatacca aaattgatgt
     3001 taatcaagtt ttgttgctga aaagataggc gactttaccg ggtgagatca aaaaacagag
     3061 tttgttgttc attatttgag ctgatttgtg agaatgatat agagtgaggt gtgtatggag
     3121 ggcgttcggt aggcctgata agaggcgcat caggcattga tgctcgactg tcggatgcgg
     3181 cggaacgcct tatccaaccc acagaatcag gagcgcatca ggtaccggca aggttacctg
     3241 atgcgacgag ggcatttacc cgagggtttt gaacgcttta atgcgctgta aatgcgggga
     3301 gatattcttg aatttgtgcg tctgctcttc gtcccagaca atctcgtaat aatgatgcaa
     3361 ctcttcagat gtccgctggc tgttaagcgc ttcatcatta cgcgacaaaa tcaccaggca
     3421 acgatcgcga ttcttctcac ggaagttggt cacacactta gtggcaatat cggcatactc
     3481 ttccgggcga tcaatcttcc cttccatgtt ctcataaggg aacaaattgg ggttgaagat
     3541 cacctggcgg atatcacaga gaaaaccaat ccgctcagcc caataaccgc ccagaccaac
     3601 accacaaatg agcgggcgct cgtcgacgtt cagttgcaac attttgtcca cttctttgag
     3661 caaatgctgc atatcatgtt ttggatgccg cgtactgtag cttattagcc gtacatccgg
     3721 gtcaataaac tgcaattgta agactttctc gtggttaccc ggactgttag agtcaaaacc
     3781 gtgcaaatag ataatcatcg cttcctcaca taagccaggg ttaatgacct gccttctctt
     3841 cctgccagcg ttcatgtaac tgattcagac gggcgctgat cgctttccag cgagccgagt
     3901 ccatcagttc ctgtcgcgaa aatgaacctt tatgatacaa acgtgtaaca cgttctgcct
     3961 tgatcggtga cagattatct aacacgctga cggccccttt acgattattg cagaccagga
     4021 tcatatcgca acctgcatcc agtgatgcct gtccacgctc ggcataactg cccataatcg
     4081 ctgcgccttc catcgataaa tcgtcagaga aaatcacgcc gtcaaaaccc aattcctgac
     4141 gcaaaacggt tttcagccag tagggagaac cgctcgccgg acgcggatca acatcactgt
     4201 agatcacatg cgcaggcata atggcgtcga gtttattttc gcggattaag gaactgaaga
     4261 ccgacatatc tttagcgcga atctccgctt gcggacgtgg gtcgcacggt gtttctttgt
     4321 gtgagtctgc cgttactgca ccgtgacctg ggaagtgttt cccggtagtt ttcattccgg
     4381 cttcatgcat accatcaata aaccggctgg caattgccag ggctttttgt ggatcggcat
     4441 gataagaacg ctcgccaatc gccgcgctga tatgcccgac gtccagcact ggcgcaaagc
     4501 tgatatcaat atccatagca atcatttcgc tggccatcaa ccaacctgcc tcttgcgcca
     4561 gttttccgcc ttcttccatt cccaacagcg cagcgaatga ttgtgccgct ggcaagcggg
     4621 taaaaccttc acgaaaacgc tgcacgcgtc caccttcctg atctaccgcc accaccagat
     4681 gatttcgcga tgctgcgcgg atctggcgca ccagttcacg taactgggca ggatcatgat
     4741 agtttcgcgt aaagagaatc agccctccca ccagcggatg cgccagtatt tcacgctctt
     4801 ccgcgtccag ttcgtaacct tcgacatcca acattactgg acccacactg ctctccttat
     4861 tgttttatta atagctgccg ccaggtgtca tcggccagcc tgataaattg ttgatcgccg
     4921 gtttgtcgcc agcggtactc aaaccaccct gctttgagca tcagcagcca gggaaaccat
     4981 cgcctgacct gacgccataa ttgcgccgga taaatcttcg cgcgagtggc atagtcattg
     5041 accaattgcc gatgctggtc agtattttcc acccacaccg ccgccagttc cagcgcgata
     5101 tcaccatctc cggcatactc ccagtcgatg agttttaacc ctgacgcgct atgcactaaa
     5161 tttccggcgt ggacatccat atgcaatgga cttaagcgta aaagccgtgg ttcccgcgct
     5221 ttgcgcagac gttttaacat tcgcagccaa cccactgtcc gccgcgccgg atcgctttgc
     5281 tgccagtaca gttccagtaa cggcaacagc gttattcgcc agccaaaacg cggttgttga
     5341 tgtagataat acagcaagcc tgccagttcg ttggtatccg gcaaatacgt ttttacctcg
     5401 ccgggcagat agtcaaccac catccagtca cggagatata aatgcggctt cggtgcaatg
     5461 catgcgggta gttgtgataa agcccgatac tggcgcaaga acgcggactg cggcgcatca
     5521 ggatcgtgcg gctgacgcac aacaaaacgc tggccctgat gttcaatgag aaaactcccg
     5581 ccactaagcc cactattaaa cgtcgtgacg ggatgaaact gcgggaaaaa gcgcgacagc
     5641 aattcgtcgc gcgtgagggg attattgctg cgaaacggca cctttacctg accagataat
     5701 ttcgcccgtc tgcaccagca tcagctgcat ttgtagggtc ggagcgttaa cgttgccaga
     5761 ggcgctggag tacagcacgt aatgagcgcc aacattgcgg gcaatgccta tggctttact
     5821 acgggtgcct aaactgtcct gcggcgacaa acctaattgt tgcttagcca tcgacagctg
     5881 ctgggcggaa accagggtaa atttaccgtt attagccagc gcatttcgca gcgtttcggt
     5941 cgcttctgcg gcattcaacg aaccgttagt acggttgtta acgctatcaa ccagcaggac
     6001 gctacccgca gtcacgccat cagccccaag catcttactg accatcggct gcattgcgcc
     6061 attccagtca taatggcgaa tatgcggcgc aggcggtgca gtttgatctt cgtgctcaat
     6121 tgggcctggc tgctgcggta tcgtcggcac cgatggcact gtggggacag gctgttgtgg
     6181 ctcggttggt tgttccggcg ctggtttcac ttcttctacc ggtgcaggtt cacgttgccc
     6241 cacacacccg gcaagaaaca tcgccagcgc ggtaatcaag gcgtagcgac tcatttttgt
     6301 catcaagatt caccccttac aaatatagat aaagtctgac tttgtgcgcc cccagaaaat
     6361 tggcgctgcc gtacagcgtg accgccgaat gtgcgggaat ggtaacgctg cgtggccttt
     6421 ccagaggatg catctccagc cctctggcgt cataccagta aaaacgataa tgaacggtaa
     6481 cgggttcttg cctttcgtta taaagcgttg aggatgctga aggttgaata tcagatgtcg
     6541 aaaggacggg cttttctgca ctgatgcccg cagccaataa agatgactcc atcaccagcg
     6601 attgctcatc attcaccgga atttccggat gtgaacgaca gcccaccagc actaacaacg
     6661 ccagagacac cagcccaaag catccttttc tcatcgttac agacctttat gcgccagcat
     6721 tggtcccagc ggacggccac ccaacaagtg catatggatg tggtaaacct cttgtccgcc
     6781 atggcggttg gtgttcatga tcagacgata gccatcttcg gcaatacctt cttgctcagc
     6841 aatttttgcc gctacggtga tcatgcgtcc cagcgcctgc tcatgctcag ctgacacgtc
     6901 gttcacagtc ggaatgagga tattcggaat gatcagaata tgcgttggcg cttgcggcga
     6961 aatatcgcga aacgccgtta ccagatcatc ctggtagacg atatcggagg ggatctcacg
     7021 acgaataatt ttgctgaata tagtttcttc tgccacgaca ttttcctttt tcaaatagcc
     7081 atgcgttgcg ccatgctacg ccgcgccaca ctgcgagtat agagtatggt cgagttaaac
     7141 ctgctctttc aaccttaact cacgatttct taagcaaaaa accgttttgc tgccgtatat
     7201 atcgccatta ttcccatttc tgcctgcgaa tgcgctgaaa agacattttc tgtttggttt
     7261 acacaccaaa tatgaatgcg tatatttctc atttgcattt acatacaaaa ttattcgcac
     7321 actaaatata accgctcatc accctgctcc ggcatgagcc tgacgccaac ataaaccaag
     7381 agatttcaaa tgctttcgac acaatttaac agggataatc aacatcaagc catcatcaaa
     7441 ccgtcactcc ttgccggttg catagcactg gcactattac cttccgccgc ttttgctgca
     7501 ccagccactg aagaaacggt gattgttgag ggttcagcca cagccccaga tgatggcgaa
     7561 aatgattaca acgtaacgtc tacctctgcg ggtacaaaaa tgcagatgac tcaacgtgat
     7621 attcctcagt cggtcactat tgttagccag cagcggatgg aagatcagca gttacaaacg
     7681 ctgggcgaag tgatggaaaa cacgctgggg atcagcaaaa gtcaggcgga ttccgatcgt
     7741 gctctttatt attcccgcgg attccagatc gataactata tggttgatgg tatccccacc
     7801 tattttgaat cgcgctggaa tctgggcgac gcactttctg atatggcact gtttgaacgc
     7861 gtagaagtag tgcgtggcgc gacaggcctc atgaccggga cgggtaatcc atctgcggca
     7921 attaatatgg ttcgaaaaca cgcgaccagt cgtgaattta aaggcgatgt ctcggcggaa
     7981 tacggtagct ggaacaaaga acggtatgtg gcggatttac aaagcccact caccgaagac
     8041 ggtaaaatcc gcgcacgaat tgtcggcggc taccagaata acgactcatg gctggaccgc
     8101 tacaacagtg aaaagacctt cttctccggc attgtcgatg ctgatttagg cgatcttacg
     8161 atgctttcag ccggttacga atatcagcgt attgatgtta atagcccaac ctggggcggt
     8221 ttaccgcgct ggaatactga tggcagcagc aacagttacg atcgcgcacg cagtaccgca
     8281 cctgactggg cgtacaacga taaagagatc aacaaggtct ttatgaccct gaagcagcgg
     8341 tttgctgata cctggcaagc gacgctgaat gccacccact ctgaagtcga atttgacagc
     8401 aaaatgatgt atgtcgatgc ctatgtaaac aaagcggatg gtatgctggt tgggccatac
     8461 agtaattatg gccctggttt tgattatgtc ggaggcaccg gttggaacag cggcaaacgt
     8521 aaagttgatg cgctggatct gttcgctgac ggtagttatg aattgtttgg tcgtcagcac
     8581 aatttaatgt ttggtggcag ttacagcaaa caaaacaatc gttacttcag ttcatgggcc
     8641 aacattttcc cggatgaaat tggcagtttc tacaacttta atggcaattt cccacaaacc
     8701 gacaggtcac cacagagtct ggcgcaggac gataccacac atatgaaatc gttatatgct
     8761 gccactcgtg tcacccttgc cgatccgctg catctgatcc tcggcgcacg ttataccaag
     8821 tggcgggttg atacgctgac ttacagcatg gagaaaaacc acaccacgcc ttatgctgga
     8881 ctggtgtttg acatcaatga taactggtcg acctacgcca gctatacctc tatttttcag
     8941 ccgcaaaatg atcgtgacag ttcaggcaaa tatctggcac caatcaccgg taacaactac
     9001 gagctgggtc tgaaatcgga ctggatgaat agccgtctga ccaccacgtt agccatcttc
     9061 cgtattgagc aggataatgt cgctcagtcc accggtacac ctatccccgg cagcaacggc
     9121 gaaaccgcct ataaagcggt ggatgggaca gtcagtaaag gtgtggaatt tgaactcaac
     9181 ggcgcaatta ccgacaactg gcagctgacg tttggcgcaa cgcgctatat tgcagaggat
     9241 aacgaaggaa acgccgttaa tcctaatctg ccacgcacca cggttaaaat gttcaccagc
     9301 tatcggttgc ctgtcatgcc agagttgacg gtcggcggtg gtgttaactg gcaaaatcgc
     9361 gtgtataccg acaccgtgac accgtatggc accttccgcg ccgagcaagg tagctacgcg
     9421 ctggtggatc tcttcacccg ctaccaggtg acgaaaaact tctcgttaca ggggaacgtc
     9481 aataacctgt tcgacaaaac ctacgatacc aacgtggaag gttctattgt ctacggcgca
     9541 ccgcgtaatt taagcattac cggcacgtat caattctgaa taacgcctgt aaaaaaggca
     9601 gccatctggc tgccttagtc tccccaacgt cttacggatt agtggttacg gatgtactca
     9661 tccatctcgg ttttcaggtt atcggattta gtaccgaaaa tcgcctgaac accagaacca
     9721 gcaaccacta cgcccgctgc gcccagtttc ttcaggccag cctgatccac tttagacaca
     9781 tcagcaacgc tgacgcgcag acgggtaata catgcgtcga ggttagtaat gttttcttta
     9841 ccaccaaatg cagcaaccag agccggtgcc atttcgctgg tacctgtcgc ttttgcgtct
     9901 tcagtcgcgt cttcacgacc cggcgttttc agatccagtg ctttaatcag cacgcggaag
     9961 atggtgtagt aaacaatggc ataaccgata ccgacgatcg ggaacagcca cagtttgctg
    10021 ctgttaccag acagaacgat gaagtcgatc agaccgtgcg agaacgacgt accgtcacgc
    10081 atccccagaa gaatacagat tgggaatgcc aggcctgcca gaatcgcgtg gatgatgtac
    10141 aggatcggcg caacgaacat gaaggagaac tcgatcggct cggtgatacc ggtcaggaac
    10201 gaggtcagcg ccgcggagat cataataccg cccactttcg cgcggttttc tggtttagca
    10261 gagtgccaga tagcaattgc ggcagctggc agaccgtaca ttttgaacag gaagccacca
    10321 gacagtttac ccgcagtcgg gtcacccgcc atataacgcg gaatgtcgcc gtggaaaacc
    10381 tgacctgctg cgttggtgta ttcaccaatc tgcatctgga aaggtacgtt ccagatgtgg
    10441 tgcagaccaa acggtaccag gcaacgttcg atgaaaccgt aaatgccaaa cgcaactacc
    10501 gggttctggt aagcagccca ctgagagaag gtctggattg cagagccaat aggcggccaa
    10561 atgaaggaca gcacaacgcc agtaaagatg gcagtcaggc ctgaaatgat cggcacaaag
    10621 cgtttaccgg caaagaagcc aagatactca ggcagcttaa tacggtagaa acggttaaac
    10681 atgtacgctg cgatcgcacc ggagataatc cccccgagta cgccagtatc cgccaggtgt
    10741 ttagaggcga tttcttcagc aggtaaatgc agtaccagtg gcgcaaccac ggccatggtt
    10801 ttaaccatga tgccataggc aacaactgcg gccagcgcgg atacgccatc gttattggta
    10861 aagccgaggg cgacaccgat cgcaaaaatc agtggcatgt ttgcaaagac ggaaccgcct
    10921 gcttctgcca taacatgcga tacaacggcg ggcagccagc tgaaattcgc ggaaccgacg
    10981 cccagcagaa tacctgcgat aggcagtacg gataccggca gcatcagcga tttaccgacc
    11041 ttttgcaggt tagcaaatgc attcttaaac ataattgaga gtgctcctga gtatgggtgc
    11101 tttttttacg ttctcacgcg tggcaagggg ggagtgcctc gccgtgtaca gggcatctaa
    11161 gcgcccttta tttattacac agagtaaaat aattcagtgc cgatttgttt gacggctatc
    11221 acgtttcaac ttcagatcat tggagaagtt gcacattttg acaaaacata tgtcacaata
    11281 tttcaaacgt ggttattcac cgcccgattt tcggcggtga actttactcg ttttagccat
    11341 taattacgag ctttaaaaaa actcattcaa cggatggatt gaaggcggga agcatcgatg
    11401 tgaaacagac gggcgaagtt atcggtggtt acctgcgcca gttcttcaac ggcaacacct
    11461 ttcaacacag ccatgtattc tgcaacgtca cgaaccatcg caggttgatt ctcttttcct
    11521 cgatgcggta ctggcgcaag gtaaggtgag tcagtttcca ccagtaaccg atccaggggg
    11581 acataacgcg cagcatcgcg cagttgctcc gcattacgga aggtcacaat gccggaaaag
    11641 gagatgtaaa atccgagatc cagtaattta cccgccgttt ctctgtcctc tgtaaaacag
    11701 tgtagtacgc caccgcaatc cgtcactttt tcttcgcgca gaattgccag cgtatcggcg
    11761 cgggcgtcac gggtgtggac gataaccggc ttgttcagtt cacgaccaat ctggatatga
    11821 tggatgaagg actcttgctg acgtacttta gtttccggcg tgtaataata atccagcccg
    11881 gtttcaccca gcgctacaac gccctcttct gccgccagac gacgtaaatc ttctacatcg
    11941 tagggatcat tctggttgag tggatgcacg ccacaagaaa atacgacgtt gtcgcgttcg
    12001 cctaccagat cccgcatgtg taaataaccc ggtaatgttg tggcgactgc cagacaaaat
    12061 ttcacatcgc gtgcggcggc tttcgccaga acgtcatcca cgtccttatg caaagattca
    12121 taatccagac catcgagatg gcagtgtgag tcgactaaaa acatgatgtc tctcttaaag
    12181 atgaggaacc ggtagcacaa cgcccggttg caggtaatgc tcaatacgca gtaaaagatc
    12241 ggtgatgaga agctcgcggt tgatacctgt gacagacatt aactgttcac gaatgtggca
    12301 aacatccccc agtatagcct gcaggcgcga gggagaaaga tggtttgcca gttcgacgac
    12361 cagccccggc acatcaacat tggtcacgtg cgcagcgcca taatggcgtt ttagcgcatc
    12421 catcagcaac gttgccagcc agtgtaaacg cgccggagct tgttcattat taagggccgc
    12481 tagcagcgaa taccagtcgc ccgattgcac gccatatgcc agcgcctgac acaatgtttc
    12541 acgagcctgc cagttatctc cctgaaacaa cgccagtgcc gccccaggcg aaccggcgct
    12601 taagcgcaat gcggcaagta gtgcatcctg tgacattgtc acttcgcgtg aaagccaggt
    12661 cacggcgtac tgttccggcg gcggcgcaag gtaatgtaac cgacaacgac tacgtaatgt
    12721 tgccagtaaa cgttctggct cgcgggtagc aaggaaaaac cacgtctctg ctggtggctc
    12781 ttcaagcgtt ttcagcaatg cgttagccgc ggcgtcggtt agtaaggcag catcggttac
    12841 ccagacaact ttcgcaccac ctaagcgtgc gtgctcattc agcttttcgg tgacctcacg
    12901 taccgcatca atgcccagcg catttttccc tttttcggga gccagggtgt agtaatcggg
    12961 atgtgtgcca gcctgcatca actgacatcc acgacagtga ccgcaacttt tgtggccctg
    13021 cggttgttgg cagagtaaat aacggctcag ggcgtagatt aaagcatcat cgcccatgcc
    13081 cggtaacgcc tgaatgagta gcgcatggtg acctcttccg gcctgatagc tggctaccag
    13141 tttttcgaaa tcaggtcgta accatggata ccatctcatg cgtccaactc cttcacccaa
    13201 ttggtcacgg tagtgcggat tgcatccatc acggcctcca gcggctgggt ggcatcaatg
    13261 gtatgaatgc ttttatcttg tgctgccagt tccagatagc gggcgcgggt gcgattaaag
    13321 aaatcgaatg actcttgctc aatacgatcc agctcaccac gggcgcgagc acgttttaag
    13381 ccgacctctg gggtgacatc aagataaagc gttaagtcag ggcgaaaatc cccgagaaca
    13441 gcatcacgca gtgttgccag catatgttgg tcaataccac gtcctccacc ctgataggct
    13501 tgagtggaga gatcgtggcg atcgccaatc acccaggtgc cgttagccag cgcaggtttg
    13561 atgaccgttt ctaccagttg aacgcgcgcg gcataaaaca tcaaaacttc ggctttatcg
    13621 gtaatgactt catcgcctac cgatttgata tccagcacca ggcttcttaa cttttcggca
    13681 agttgcgtac cgccaggttc ccgagtgaaa accatgtcgc ggatacccag ttgctcaagc
    13741 gtctcaacca ccacgttacg cgcggtagtt ttgcctgcgc cttccagccc ctcaatgacg
    13801 atatacttac tgcgcatttt tttccttaag cactttcaga taatcctgca cagacttgtt
    13861 atgactggca agattggtat taaacgtgtg accaccttta ccatcggcca caaaatagag
    13921 atacggcgtt tttgccggat gcgcagcagc cttcagcgaa tccgcccccg gcgtcgctat
    13981 cgcacctggc ggcagaccgg taatggtata ggtgttatac gctgtcggcg tttccaggtc
    14041 tgcacgagaa agtttgccat tataacgctc tcccatcccg taaatcacgg tcgggtcggt
    14101 ctgcaggcgc ataccaatgc gtaaacggtt gataaatact gaggcaacct gatcgcgttc
    14161 actggcaacg gcggtttctt tttcgataat tgatgccatc gtcaccaact ggtttttatc
    14221 tttataaggc agaccgtccg cacgcccttc ccaggcgcta tcgaccgctt tcaccatttt
    14281 cttgtgcgct cgtttgagta acgcgacatc ggtggtattg gcggtataca tccaggtgtc
    14341 tggccagaac caaccttcaa tccactccgg gttttccagt tcaagtgcct gcgctacggt
    14401 ggcgtactta tcgtcgctca gcgtgtgctt gatatacgga gcctcacgca attgcttgag
    14461 gtagtcgctc agacgcatcc cttctaccag tcgcagcggg aactgtgctt ctttaccgct
    14521 ttccaacaat ttcagcatct cgcgcacggt catctgcggt gtaaagcggt aagtcccggc
    14581 tttaaagtga gaaagatccg gttcgatacg cagcagccat tggaaaaccc gtgggcgatt
    14641 gatgatctta tcggcataaa gctgttcacc gagcgccaga cgtccggtcc ctggcttcag
    14701 ggtaaatatc gtctcttctt tgataagcaa tttgctgtcg gcaagatggc gaaccttcca
    14761 gacgcccaca ccagcggcga tacccagtac caccagcaat aacaagatta tcaataacac
    14821 ttttttcatg actaattcgg gcgctcacaa agtggggcta aatattcata taacgttgct
    14881 gacgaaaagg agacatcgcc acaggcacgt acgggcatca ctggcattaa cgcattacaa
    14941 ataaccatct catctgcctg caacgcctct tccagagagg cttgcacttc gacaagctga
    15001 taagaggatt gtgccagcaa acggatacag aattgtcgca taatgccgtt aacacctgcc
    15061 tgatccagtc gcggcgtata aactacgttg cccttccgcc agaacaaatt agccgcacag
    15121 cattccgtaa cccacccttc gctgtcaagg accagcgcct catcagcgtt tgtctgctca
    15181 agatgagagc ggatcaatac ttgctcaagc cgattaagat gtttaatacc tgcaagatga
    15241 ggattgcgcc ccagccgcac cgggcttagc gccaacgtca tcccttcgtt acgcaaacgg
    15301 tcgtaatgtg caggataagc cgtaacggag agaatccgcg ttgccggtcc actgttcaat
    15361 gtgctgtacc ctcgcccgcc actaccgcga ctgatcacga ctttcagtac accattttgc
    15421 tgttctgctg ccagcgtttt catctcttgt tcaagctgag gccagaagtc acaggaaatc
    15481 atcaaccgct gacaagcatc ctgtagtcgc tggatatgcg ccgataacaa actgacttta
    15541 ccgtcgataa ctctggcggt ggtaaaacaa ccatcaccaa actgcgttgc ccgatcgctt
    15601 actgccagcg attcctgctt atgaccgtta attaagaaca taccggctcc ttatcagaga
    15661 attgttagtg tggcagcatg ttcactacgg aacaagtcgg aataaaagct aagaaaaaag
    15721 gcccgcaagc ggacctttta taagggtgga aaatgacaat ttagatcttt ttaaagatca
    15781 aagaaccatt agtgccaccg aagccgaagg aattacacag agtgtattcc attccgctaa
    15841 cctgacgcgc ttcgtgcggt acgaaatcca aatcgcaacc ttcatccggg ttatccaggt
    15901 tgatggttgg cggaacagcc tgatcgcgca gcgcaaggat ggagtagata gattctactg
    15961 cacccgccgc acctaacagg tgaccggtca tagatttcgt ggagcttacc aacacgcggc
    16021 ttgcagcttc accgaagatg gttttcaccg cctgcgcttc agctttatcg ccagccggcg
    16081 tagaagtacc gtgcgcgtta acgtagccaa tctgactcgc ttcaatgcct gcatcacgca
    16141 gagcatttgc catcgccaga gctgcgcctg cgccattttc tggcggtgac gtcatatgat
    16201 aagcatcgct gctcatacca aagccgacga gttcagcgta aattttcgca ccgcgttttt
    16261 tcgcgtgttc gtactcttca agtaccagca taccggcacc atcgcccagt acgaaaccat
    16321 cacgctcttt atcccacggg cggctcgccg cttgcgggtt atcattgcgg gtagataatg
    16381 cgcgtgccgc gccaaaacca ccaacgccca gcggcgtact ggctttctct gcgccacctg
    16441 caaccatcac gtcagcatcg ccatacgcga taatacgcgc agcatggcca atgttgtgca
    16501 cgccggaagt acaggcggtc gcgatagaga tgcttgggcc acgcaggcca tacatgatag
    16561 tcagatgacc tgccaccatg ttcacaatcg ttgacggaac gaagaatggg ctgatcttac
    16621 gtggaccacc gttcatcaga gatgtgtggt tttcttcgat cagtccgagg ccgccaatcc
    16681 cggagccaat tgcggcacca atgcgggttg cgttctcttc cgttatttca aggccagaat
    16741 cctgcatggc ctgaacgcca gcgacaattc catattgaat gaaggcatcc atcttgcgct
    16801 gttctttgcg cgagataatg tcctcacagt taaaatcctt tactaagcca gcaaatttcg
    16861 ttgcataggc gctagtatcg aaatggtcga ttaggctgat gccactctga ccggcaagca
    16921 gagctttcca ggtagactct acggtattgc cgacaggaga caacatgccc agtccggtca
    16981 caactacacg acgcttagac acgtttgtcc tccagggagg gaaaaaatga ttctagtggg
    17041 acaaaaagat aaaactcagg cggtcgaacg accgcctgga gatgttcact tacgcctggt
    17101 ggccgttgat gtaatcaatg gcagcctgaa cggtggtgat tttctcagct tcttcgtccg
    17161 gaatctcagt atcaaactct tcttccagag ccattaccag ctcaacggtg tcaagagaat
    17221 ccgcgcccag gtcttcaacg aaagaagcat tgttggtaac ttcttcctgc ttaacgccca
    17281 gctgttcgcc gataattttc ttaacgcgtt cttcgatagt gctcatactc ttaaatttcc
    17341 tatcaaaact cgctttcgcg atggttttcg tagtgtataa aatgttgaaa aatttgcaac
    17401 taaatcccgg caggtcttac cacgatttta cgttattttg aggccttacc ccccaataac
    17461 gcaaatcatt ttgcactaat tattactcat aaccacgcag actgcgcgca acatgagcat
    17521 tttgtgcaaa tcgcggtcag accatgtaca tcccgccgtt cacatgcaaa gtttcacccg
    17581 tgatgtaagc tgcttcgtcg gatgccagga atgcaaccgc gttggcgatt tcctgtgcgc
    17641 cgccgaggcg acccgcagga acctgcgcca ggatacccgc acgctggtca tcgctcagcg
    17701 cacgtgtcat gtccgtttca ataaagcccg gagcaacaac gtttacagta ataccgcgtg
    17761 acgcaacttc gcgcgccagt gatttactga agccgatcaa gcccgctttc gccgcagcgt
    17821 agttggcctg accgccattt cccatggtac caaccacaga accgatagtg ataatacgac
    17881 catgacgctt tttcatcata gcgcgcatta ccgcttttga cagacggaaa acagatgaaa
    17941 ggttggtttc gataatatcg ttccactctt catctttcat tcgcattaac aggttatcac
    18001 gagtgatacc ggcattattg accaggatat ccacttcacc aaattctgcg cgaatttttt
    18061 ccagaacaga ttcgatagat gccgggtcgg tcacattcaa catcagacct ttgccgttgg
    18121 cacctaaata atcactgatc gcctgagcgc cattttcact ggtcgcagtg ccaataactt
    18181 tcgcgccacg ggctgcgagc gtttcagcaa ttgcgcggcc aattccgcgg cttgcaccgg
    18241 ttaccagtgc gatttttcct tcaaaattca tgattttcct cttttaaagc tcgagcgccg
    18301 ctgccatcgc tgaaggttcg ttcagcgccg aggcggtcag ggtgtcgaca atgcgtttcg
    18361 tcaggccagt aagcactttg cccgggccga cttcatagag atgttctacg ccttgcgctg
    18421 ccatgtattc aacagacttc gtccactgaa ccgggttata caactgacgt accagtgcgt
    18481 cacgaatggc atcaccattg gtttcgcatt tcacatcaac gttattcaca acaggaactg
    18541 ttggtgcgtt aaaggtgatt ttcgctaatt ctactgccag tttgtcggct gctggtttca
    18601 tcagcgcaca gtgagacggt acgctcactg gtagcggcag agcgcgtttt gcgcccgcag
    18661 ctttacaagc agcacccgca cgctcaaccg cttctttatg accggcaata accacctgtc
    18721 ccggagagtt aaagtttacc ggagaaacga cctgaccttc tgcagcttct tcacacgctt
    18781 tcgcaataga cgcatcatcc agaccgatga ttgccgccat agcacccgtt ccttccggta
    18841 cggcttcttg catgaacttg ccgcgcatct caaccagacg caccgcatca gcgaaatcaa
    18901 tcacaccagc gcaaaccagc gcggagtatt cccccaggct gtgaccggcc atcattgccg
    18961 gtgctttacc gccctgctgc tgccatacgc gatacagcgc aacagatgca gtcaacagcg
    19021 ctggctgggt ttgccaggtt ttattcagtt cttcagctgg cccctgctgg gtcagcgccc
    19081 acaggtcgta gcccagcgcc gcagaagctt cagcaaacgt ttcttcgaca attggatagc
    19141 tcgccgccat atcagccagc attccaacgg tttgagaacc ctgtccaggg aacacaaatg
    19201 caaattgcgt catgttttaa tccttatcct agaaacgaac cagcgcggag ccccaggtga
    19261 atccaccgcc aaaggcttca agcagaacca actgccccgg cttaatgcgc ccgtcgcgta
    19321 cagcttcatc cagagcgcac gggacagagg ccgcagaggt attaccgtgg cgatccagcg
    19381 tcaccacgac attgtccatc gacatgccga gttttttcgc tgttgcactg ataatacgca
    19441 ggttagcctg atgcggaacc agccagtcca gttgagaacg gtcaagatta ttcgccgtca
    19501 gcgtctcatc aacgatgtgc gccagttctg ttaccgcaac cttgaagact tcgttgcccg
    19561 ccatcgtcag atgaattgaa ttctctggat tcacacggtc agcattaggc agcgtcagca
    19621 actcaccata gctaccgtcg gcatgcagat gggtggagat gattcccggc tcttcagagg
    19681 cagccagcac cgcagcgccc gcgccatcgc caaaaataat aatagtccca cgatctgttg
    19741 gatcgcaggt gcgcgccagt acatcggaac cgacgaccag agcatacttc accgccccag
    19801 atttcacgta ttgatcggct acgcttaatg cataggtgaa acctgcgcag gctgctgcaa
    19861 cgtcaaatgc cgggcaacct ttaatgccca gcatgctttg aatctgacaa gctgcgctcg
    19921 ggaaagcgtg cgtagcagaa gtcgttgcca caacgatcag gccaatctgg tctttctcaa
    19981 tgcccgccat ctcaattgcg cgtgtcgccg cttcaaagcc catggttgaa acggtttcgt
    20041 ttggcgcggc aatgtggcgt tcgcggatac cggtacgagt gacaatccac tcgtcagagg
    20101 tgtccaccat tttttccaaa tcggcgtttg tccgcacttg ttcgggcaga tagctgccag
    20161 taccaataat cttcgtatac atgtacgctc agtcactttt cggttatata ccgtcacttg
    20221 caaactgcga gttcgctggc agcgtcctgc taccgcagag ttccgctttt gccaccgtcc
    20281 agcagctcaa aaccagctgg gtatacagat tccaggcgag cggcaattcg ctgaggaact
    20341 tgtcgctgca ccgcctgcac tgcctgttca atcgcgaccg caaaagctcg ctgattggct
    20401 gcaccatgac tttttatcac cgtgccgcgc aatcctaaca gacaggcgcc gttatactgg
    20461 tcggggttga ggtgactgaa tcgcctcgtc aggctctttt gtagccaacg ctttaataac
    20521 agtagccacc acgaccgttt tttcccttca ccctgagatt tcagcagaga aaggaacatc
    20581 ctgacaacac cttccatcgt ctttaatgtg acatttcctg taaagccgtc acaaaccagc
    20641 acatctgtct tgccagttaa caactcattg gcttcaagat agccgatata attgatagaa
    20701 gggattgttt taagcaccgc tgaggcatcc cgaatactgt cgagaccctt tacttcttct
    20761 tcaccaatat tgagcaacgc cacgcgagga ttaggaattt ccaccacctc ttcagccaga
    20821 actgagccca taatggcaaa ttgcaccaac attgtactgt cacaatcgac gttggcccct
    20881 aaatcgagga ccaccgtttt gcccttttgc tgatgcggta ataccgtcac cagcgccgga
    20941 cgctcaatcc cctccagggg cttgagtaat aattttgcca gccccattag cgccccggta
    21001 ttaccggcac tgacacaggc ttgcgctcga ccttctttca ccagctccag ggccacgcgc
    21061 attgaactcc cacgactggc gcggatagct tgcgaaggcc gggcatcact ggcgataact
    21121 gactgcgcag gaataatctg cagacgcgaa cgttgttcaa agtcagcttt agcaagtaat
    21181 ggcgtgatgg cgtcgggatt gccgactaaa agaagagtga gttgcgaatt agaattcagt
    21241 gcctgcaatg ctgcaggcac tgtcacggaa gggccaaaat cccctcccat gacatctaac
    21301 gccagggtta gacgtgtcaa ggtatcgtcg ccgcccggtt tggtctttcc ccagttgcct
    21361 ggggaaaatc ctcactaagc ttcatcacgc agacgcgtaa ttacttagcg atgaccttgc
    21421 ggccgcggta gtaaccgtcg gcagtgatgt ggtgacgcag gtgtttttca ccagaagttt
    21481 tgtctacaga caggctggtg actgcggtca gcgcgtcatg ggaacgacgc atgccacgtt
    21541 tggaacgggt tggtttattc tgttgtacgg ccatggacct tactcctcaa ttacggttta
    21601 tccccgatcc aacggggagc accaattact tacgctttaa gctggctaat acggcaaatg
    21661 ggtttggctt ttgcgcttct tcaggcagtt caccaaagac catgtccgct tcggacactt
    21721 cacagtgttc agaatcatgc accggaacta ccggcaaggc gaggatgatt tcatcttcaa
    21781 ccattgcaag cagatcgatt tcaccgaatt cgttaacctc aatcggttca tacgcttccg
    21841 gcagtgcttc agcctgttcg tctgaacgca caggactaaa acaatacgtt gtgtagacct
    21901 gatgagtaaa cggcttcccg caacgctgac actcgagcgt taccgtcacc ttcgcatcgc
    21961 cgtttaacac tgcgagacgt tggttatcga tagcgaacga catggagcat tccacatcac
    22021 tgtccacact gactacggat tcggcgacgc gctcaacctg atcaggagta tagataccct
    22081 ggtaatcaag gcgtttttga gccgtacgaa ccggatcgag agtcaggggt aattttacct
    22141 tttgcatagg gcgcgcatat taactttgta acgtcataga gtcaaagaaa aaggcagcct
    22201 gtggttgcct tttgccaata attcgcacac attgcgggtt actgctttat tttcgttcag
    22261 tgctgataac gaacatcaac ctgcaaaacg aagcgcatag tttaaaatgg ctatcatcaa
    22321 tacgctatat ctgatggaaa aaaatatgcc tgaacttatt ttagcctcca cctcgccctg
    22381 gcgtcgcgct cttctggaaa aactgcaaat ctcttttgaa tgtgcagcac ccgaggtcga
    22441 cgaaactcca cgcagcgacg aatcaccgcg acagttggtg cttcgactgg cacaagaaaa
    22501 agcgcaatct ctggcgtcac gttatccgga tcatttaatt attggttcag accaggtatg
    22561 tgttcttgat ggcgaaatca ccggtaaacc gttaacggaa gaaaatgccc gtctgcaatt
    22621 acgcaaagcc agcggcaata tcgtcacctt ctatactgga ctggcgttgt ttaattcggc
    22681 gaatgggcat ctacaaacag aagtggagcc ttttgacgtc catttccgtc acctgagcga
    22741 ggcggagatt gataattacg tgcgtaaaga gcatcccctg cactgcgcgg gtagctttaa
    22801 gagtgaagga tttggcatta cgctgtttga gcgtttagag gggcgtgatc ctaacacgct
    22861 ggttggttta ccgctaatcg cgctgtgtca gatgttacgt cgggaaggaa aaaacccgct
    22921 gatgggatag ttttttgcgc cggatgcggt tacgtcgcat ccggcaatcg gtgctggcgg
    22981 cctgatgcgg cataaacgcc ttatcaggcc aaccgcccat tatcatgctt atatgctcgt
    23041 attagcgcgc gttacgcagt ttttgcaaac aacgcttcaa accatcatcc atcggcgctt
    23101 cgatacgcat cacctcaccg gtccccggat gggtaaactt caacgctgcg gcgtgcagga
    23161 acagacgatt taatcccgtg cctgcttcag tgagctgtct gtcaaattca cggtcaccgt
    23221 agcgatcgtc aaaggcaatc ggatgacccg catattgtgt atgcacacgg atctgatgag
    23281 tacgccctgt taccgggcta caacgcacca gggtggcaaa tgcatagcgc tcttccactt
    23341 taaagcgtgt ttccgacggt ttgccttcct gactcacacg cacgatacgt tcgccgcttt
    23401 gcagaatatt tttcagtaac ggcgcttgaa cgctcttcac atgcgactgc cactgaccgc
    23461 gcaccagcgc caggtaatct ttttgcatcc ctttttcacg taattgctca tgcagagaac
    23521 gcaacgccga gcgttttttc gctaccagca acacacctga ggtgtcccgg tcaagacgat
    23581 gaaccagttc aaggaaccgc gcttccgggc gcaacgcccg caaaccttcg ataacgccga
    23641 agcttaaacc actaccgcca tgtaccgccg taccggaagg tttattcagc accaggatat
    23701 ggtcatcttc atataagatg acgtccgcca gcgccgccac cttttgcaga tgtggcgaaa
    23761 ccgcctcttc ttcccgttca gcaacgcgaa ccggtgggat acgcacctca tcacccgctt
    23821 cgagtttata ttcaggctta atacgttttt tgttcacccg cacttcgcct ttacgcaaaa
    23881 tacggtaaat catacttttt ggtacacctt tcaattgggt acgcaaaaag ttatcgatac
    23941 gttgccccgc ttcgtcagcg gtgatagcaa caatttttac ggatggagtc tctgttttca
    24001 tggtgggcga ttctaattag ccaacaggat tcgcgccact catttttcta tgcttatatt
    24061 tagttttgca ccttattact tcactacatg atcactttat tgatggttat taaaccaatc
    24121 accagcaaga agtgaaaaaa ctgtgagtaa gcgggtgata aatggtaaaa gtcatcttgc
    24181 tataacaagg cttgcagtgg aataatgagg ccgtttccgt gtccatcctt gttaaaacaa
    24241 gaaattttac ggaataaccc attttgcccg accgatcatc cacgcagcaa tggcgtaaga
    24301 cgtattgatc tttcaggcag ttagcgggct gcgggttgca gtccttaccg gtagatggaa
    24361 atatttctgg agagtaatac ccagtctgtt tctttgataa ttgcgctgtt tttccgcatg
    24421 aaaaacgggc aaccgacact ctgcgcctct ttgagctgac gataaccgtg aggttggcga
    24481 cgcgactaga cacgaggcca tcggttcaca cccggaaagg cgttactttg cccgcagctt
    24541 agtcgtcaat gtaagaataa tgagtaagtt acgatgaaaa gaatgttaat caacgcaact
    24601 cagcaggaag agttgcgcgt tgcccttgta gatgggcagc gtctgtatga cctggatatc
    24661 gaaagtccag ggcacgagca gaaaaaggca aacatctaca aaggtaaaat cacccgcatt
    24721 gaaccgagtc tggaagctgc ttttgttgat tacggcgctg aacgtcacgg tttcctccca
    24781 ctaaaagaaa ttgcccgcga atatttccct gctaactaca gtgctcatgg tcgtcccaac
    24841 attaaagatg tgttgcgtga aggtcaggaa gtcattgttc agatcgataa agaagagcgc
    24901 ggcaacaaag gcgcggcatt aaccaccttt atcagtctgg cgggtagcta tctggttctg
    24961 atgccgaaca acccgcgcgc gggtggtatt tctcgtcgta tcgaaggcga cgaccgtacc
    25021 gaattaaaag aagcactggc aagccttgaa ctgccggaag gcatggggct tatcgtgcgc
    25081 accgctggcg tcggcaaatc tgctgaggcg ctgcaatggg atttaagctt ccgtctgaaa
    25141 cactgggaag ccatcaaaaa agccgctgaa agccgcccgg ctccgttcct gattcatcag
    25201 gagagcaacg taatcgttcg cgcattccgc gattacttac gccaggacat cggcgaaatc
    25261 cttatcgata acccgaaagt gctcgaactg gcacgtcagc atatcgctgc attaggccgc
    25321 ccggatttca gcagcaaaat caaactgtac accggcgaga tcccgctgtt cagccactac
    25381 cagatcgagt cgcagatcga gtccgccttc cagcgtgaag ttcgtctgcc atccggtggt
    25441 tccattgtta tcgacagcac cgaagcgtta acggccatcg acatcaactc cgcacgcgcg
    25501 acccgcggcg gcgatatcga agaaaccgcg tttaacacca acctcgaagc tgccgatgag
    25561 attgctcgtc agttgcgcct gcgtgacctc ggcggcctga ttgttatcga cttcatcgac
    25621 atgacgccag tacgccacca gcgtgcggta gaaaaccgtc tgcgtgaagc ggtgcgtcag
    25681 gaccgggcgc gtattcaaat cagccatatt tctcgctttg gcctgctgga aatgtcccgt
    25741 cagcgcctga gcccatcact gggtgaatcc agccatcacg tctgcccgcg ctgctccggt
    25801 accggtaccg ttcgtgacaa cgaatcgctg tcgctctcta ttctgcgtct gatcgaagaa
    25861 gaagcgctga aagagaacac ccaggaagtt cacgccattg ttcctgtgcc aattgcttct
    25921 tacctgctga atgaaaaacg ttctgcggta aatgcgattg aaactcgtca ggacggcgta
    25981 cgctgtgtga ttgtgccaaa cgatcagatg gaaaccccgc actaccatgt gctgcgcgtg
    26041 cgcaaagggg aagaaacccc aaccttaagc tacatgctgc cgaagctgca tgaagaagcg
    26101 atggcgctgc cgtctgaaga agagttcgct gaacgtaagc gtccggaaca acctgcgctg
    26161 gcaacctttg ccatgccgga tgtgccgcca gcaccaacgc cagctgaacc tgccgcgcct
    26221 gtcgtagccc cagcacctaa atctgcaccg gcaacaccag ccgctcctgc ccaacctggg
    26281 ctgttgagcc gcttcttcgg cgcactgaaa gcgctgttca gcggtggtga agaaaccaaa
    26341 ccgtccgagc aaccaacacc gaaagcagaa gcgaaaccgg aacgtcaaca ggatcgtcgc
    26401 aagcctcgtc agaacaaccg ccgtgaccgt aatgagcgcc gcgaccctcg tagtgaacgt
    26461 actgaaggca gcgataatcg cgaagaaaac cgtcgtaatc gtcgccaggc acagcagcag
    26521 actgccgaga cgcgtgagag ccgtcagcag gcagaggtaa cggaaaaagc gcgtaccacc
    26581 gacgagcagc aaacgccgcg tcgtgaacgt agccgccgcc gtaacgatga taaacgtcag
    26641 gcgcaacaag aagtgaaggc gctgaatgtt gaagagcaat ctgttcagga aaccgaacag
    26701 gaagaacgtg tacgtccggt tcagccgcgt cgtaaacagc gtcagctcaa tcagaaagtg
    26761 cgttacgagc aaagcgtagc cgaagaagcg gtagtcgcac cggtggttga agaaactgtc
    26821 gcagccgaac caattgttca ggaagcggca gccccacgca cagaattggt gaaagttccg
    26881 ctgccagtcg tagcgcaaac tgcaccagaa cagcaagaag agaacaatgc tgataaccgt
    26941 gacaacggtg gcatgccgcg tcgttctcgc cgctcgcctc gtcacctgcg cgtaagtggt
    27001 cagcgtcgtc gtcgctatcg tgacgagcgt tatccaaccc agtcgccaat gccgttgacc
    27061 gtagcgtgcg cgtctccgga actggcctct ggcaaagtct ggatccgcta tccaattgta
    27121 cgtccgcaag atgtacaggt tgaagagcag cgcgaacagg aagaagtaca agtgcagccg
    27181 atggtgactg aggtccctgt cgccgccgct gccgaacctg ttgttagcgc gccagttgtt
    27241 gaagaagtgg ctgaagtcgt agaagccccc gttcaggttg ccgaaccgca accggaagtg
    27301 gttgaaacga cgcatcctga agtgattgct gccgcggtaa ctgaacagcc gcaggtgatt
    27361 accgagtctg atgttgccgt agcccaggaa gttgcagaac acgcagaacc ggtggttgaa
    27421 ccgcaggaag agacggcaga tattgaagaa gttgccgaaa ctgctgaggt tgtggttgct
    27481 gaacctgaag ttgttgctca acctgccgcg ccagtcgtcg ctgaagtcac agcagaagtt
    27541 gaaacggtag ctgcggttga acctgaggtc accgttgagc ataaccacgc taccgcgccg
    27601 atgacgcgcg ctccggcacc ggaatatgtt ccggaagcac cgcgtcacag tgactggcag
    27661 cgccctactt ttgccttcga aggtaaaggt gccgcaggtg gtcatacggc aacgcatcat
    27721 gcatctgccg ctcctgcgcg tccgcaacct gttgagtaat agttagctca agtaatcaag
    27781 ccctggtaac tgccagggct tttttatttc atctttgagt caacatatta aaattcatca
    27841 aatggcatcc ttgctaacca acaatacaaa ataggcaaaa aaatgcccgc tccggcgatc
    27901 ccagagcggg cagacaaaac atacccagtt tcatgatatg ttttaaagcg agcttatttg
    27961 ttgagctgga agagcgacaa tccctgcata tcggtaaatg ctttatacga tgcctgcaat
    28021 gccgtttgct gcatgatgta agatgaaata gttgcattcc agtccacatc aaccagatcg
    28081 ctcatctgct gcgtttgccc taaagcgcga tcgctaccta atgaatccag cgactccagt
    28141 tcgttcagtt gcgtgcctaa ttccgcgcga acagtcagca cattgttcag cgagtttttc
    28201 agtccgcggt tggttttatc cagtgccgca gcggcggttt ctttatccgc ttcgctatcc
    28261 gcgaccggcg ttttcagggc tgcgatggcg ctatccagca tggcaaaaag attggtttca
    28321 gaagcgctac cgtctggttc cgctaccgcg ttgctagtaa tactgtcgaa aattttgtcg
    28381 cccgtatgtc ctatcaccat cgaacgcgaa gcatcgacct gttgtttaat actttctgct
    28441 ccgccttcgt atttgccatc cgcctcgcta aacggtgcgg attctgtttt ataaccggca
    28501 aaaatgtagc gcccgttacc gtcagtggtg ttcgccagat tcagcaactg gtcacgaagc
    28561 ccctgaatat ccgtagccag cgaggcccgg tcatcgtcac tcaaggtgcc attgctggcg
    28621 tagacaattt tttcctgagc attctgtata gcggttgtga cctggctaag tacactctct
    28681 tccagtgaca ctttttgagt ggcgaaagta cgcgccagcg tgtactggct gttttgcgcc
    28741 tgtgcctggg agagaacaac agcttgtgat gcagcaatgg gatcatctga agggttaacg
    28801 actcgcttac ccgtcgacat ctgttcgccg tacttcatcc attctgcctg agaattggtg
    28861 atgccgcgca tgttttgctg gtacatcatc tgggtactga aacgcatttt atctcccctt
    28921 agcgaatgtt aatcagcgca tcaaaaatcg cgtttgccgt ctgcagaacc tgcgcattcg
    28981 cgaggtaata ctgctgaaaa cgttgcagat ttccgtactc ctcatcgaga ttgacaccgg
    29041 aaatcgactg ctgctgattg gaaagctgcg tcaccacatt accttgagtg gtgctactgg
    29101 ttttcaacgt cgcggtttta ttaccgatat cactcactaa cgaggcataa gcgtcgttaa
    29161 aggatttcgc accgcccacc gttttactgt tgctttgcag atcgagcagg gcctgaccgt
    29221 tgcggttgtc gctatcaccc gcatcttctg cgctcgccat ggcgattttc gcttcgtcgg
    29281 tgattaatac atccatgttg acgatggcgt cacttaccgg tttcagcgtg aagctgtcgt
    29341 taacggcagg cgttcctgta aacgtcaact ccagaccatc aaatgccact ttaccgttgg
    29401 catccggcgt caccgtaaaa gtggtattgc tggcaaggcg ggtgacctgc cactgattat
    29461 tatcgaacga gattttgtaa tctgtcgcca gtaccgcgga ggtatcagtt accgttgcac
    29521 cgatcgcaac gtcacctttg tttttcgtgt tttgcagaac cgcgggctta ccgatagcaa
    29581 agaaatcttc accggcatcg ccgttagcat caaatccggc tttgtgttgg gtgttgaaag
    29641 cctcggcaaa tgccagcgcc agttgtccaa gcgtattacg cgtctggtcc agatcctgag
    29701 aacggaatgt cagaatgccg cccagcgacc cggtattcag taatttctcc gggatctcaa
    29761 tattgcctgc cgtcccatca acataagcga cagtcgtacg agaagggtcg gcgctggaag
    29821 gaactgccgc aagttgccgc gccgtacttc cctgaaccag tgagtagcca ttggccatcg
    29881 tgatgttata agtgccacca tcctgaacac tgacttctac gccaacaatc tggtttaatt
    29941 cgctcaccag ttgatcgcgt tgatccagca gattgttagg tgacgcccct gcccccacgc
    30001 ctgtcaggcg ggagatctga tcgttcaggc tggcgatttg tttagcgtaa ttgttgatct
    30061 gatcaacact ggcacctatc gcgatattga cctgtttgtc ctggtcgcgc agatattgat
    30121 cggtggtttt aaactgattc accaaccctt ctgatttccc aatcagcgcc tggcgcgctg
    30181 ccggatcttc cgcgttactc accagcgttt gcaggctggt gaagaaatcc tgcatctgtg
    30241 ttgccagcga agaggtactg gtggagagca tattgtcgat tttcgacatc tgctcatagc
    30301 gggcagtcag gccgctactt tgcgtctgcg ccgcacgtaa ctggttggta ataaacgcat
    30361 catactcacg ctgcacacca gaaacgtaga cgccattgcc aacccagccg ccagcgccca
    30421 acgtgctatt ggcctgcgcc ataatagtgg tttggcgggt atatccggca acgttatagc
    30481 tggagatatt attacttgcc gtatttaacg ccgcctgggc cgcgttcagt ccgctcatgg
    30541 cgttattgat caagctggac atggaggttc cttataagcc ttcaattaca gagtattatc
    30601 ggcagcgacc cgccggactt gagttattca gaacagatta tcaatgttca tgctgtaggt
    30661 tttgctcacc ttgtcgctta tcgatttcat ctgctgaatc atgttggtga gtttgcgggc
    30721 atagtgagga tcggtggcat agcccgcgtc ctgtagggcc tgcgccccct gctccgcact
    30781 cgcggcggtc gtcacggcgg cgtagcgcgg gttacgcgtt aacagcccaa cgtaatccga
    30841 caatgcttcc agatacgagc tgtagacccg aaacttcgct tttactttct tcgcttcgcc
    30901 attttcatat tcagtcgtgg tgatttcagt gactggccct ttccagttgc cagaggcttt
    30961 gacaccaaac aggttatagc tcggctcgcc gttttcacgg cggatttgcc gttgtcccca
    31021 gccagattcc agcgccgcct gagcgaggat caaatgatgt ggcacaccac tttgctggct
    31081 tgccagttgg gcgggcagcg agagttgcgc gaggaatgct ttactgtcac ccggcagcga
    31141 atcatcgtag ttacgtggta cggccttttg caccagctgc gaaagcgtct gattttgata
    31201 acgcaccacg gtttcgagcg ggaattttat cggtgctgct ggcgtggact cctctggcaa
    31261 tggttgttct ggcgtcatct gtttaaccat catctctgcc agccccagac ctttgcccgc
    31321 cgtcatctgt tgggcaatct gctggtcata catactggta tacaggcgag tgtgctcgct
    31381 gctgaacagg ccatcttttg gtaaagcgtc gcgcatgctt ttcaacatca tctgcacgaa
    31441 catcccttcc acctggcggg ccaccggacg gatatttgcc gctggatctt cgcccgcttt
    31501 cgcctttagt tcgttgagtg attgcgcatc ccaggccgca cttgccagta gtttgctgtc
    31561 gctgatcatc agatgatttc cagttttgcc cgcagacatc ccgcactttg cattgattgc
    31621 agtatggaca tcagatccat cggcgtagcg cccagcgcat tgagcgcacg caccacgtta
    31681 ttgaggctgg cgctggaacg tacgctttgc agcgaaccgc cgctctggcg taaatcgatc
    31741 tgcgtttgtg gagtaaccac agtctgccca ccaccaaacg gtgtatctgg ctggctgaca
    31801 ttggcctgac gattaactgt tactgagaga ttcccctgcg ctaccgcgca gctgtcgagg
    31861 gtcacttcgc gattcatcac caccgaacca gtgcgcgagt taatcactac tttagcgtcc
    31921 tgcggggtga cattaacctg catattctgg atatcggcaa ggaaacggac ctgggaactg
    31981 ttgccacttg gtacgcgcac ctgaatagtc cgcgcatcta acgcggtggc gctgccatat
    32041 ccacgcacgc ggttgatggt gtcagcgatt tgctgcgcca tactgaaatc ttcgtcgtta
    32101 agttgcaaat taagggtatt cccgacgcca aactggctgg gcaattcacg ttcaataacc
    32161 gcaccattgg tgatccgtcc accgttcagt tgattcacct gaacactgct accgccagcg
    32221 gaggcccctg cgccgccaac cagaatattg ccctgcgcca gcgcatacac ctgactgtca
    32281 acgcccttaa gcggtgtcat caataacgta ccgccacgca gacttttggc atttcccatg
    32341 gaagaaacca ccacgtcaat ggtttgcccc tgacgtccaa acggtggaag tgacgctgtc
    32401 accataaccg cagcgacgtt ttttagctgc atattagtgc ccgtcggaac ggtaattccc
    32461 agctgtgaga gcatgttatt aagcgtttgt gtggtaaacg gcgtctgagt tgtctggtca
    32521 cctgtaccat caagccccac caccaggcca tagccaatca gtgagttttg ccttaccccc
    32581 tgaacactgg tgagatcgcg aatacgctca gcctgagccg ccgtggtaac cagtaaaaga
    32641 attaatgcag agagaaattt aatcaccaca gcctcactta cattggcgac aggttaagga
    32701 agaaacgctg caaccagccc atattttgcg cttcgttaat gtagccattg cctacgtatt
    32761 caatgcgcgc atctgccacc tgagtagacg gtacggtatt gctgccgctg atagtgcgtg
    32821 gattaaccac cccagagaag cgaataaatt cggtaccctg attaatggcg atctgttttt
    32881 cacccaccac atgcaggttg ccgttgacca gtacctggtc aaccgtcacc gtcaacgtac
    32941 cgctaaaggt attgctggca ttggccccgc cttttccgtt gaacgtgtta ccaccggagg
    33001 cttcgacatc ggcacgagcg ttaccaaaca acccctgcaa atagcgcggc acagtatcaa
    33061 agccaaaatt agttttaccg tcacggctgg cattcgcaga ggagcttttg ctggcgctga
    33121 cgttctcctg caacacgata gtcagcgtat cgccaatatt gcgtggtcga cgatcttcaa
    33181 acagcggttg atagccatag ttaatcggct gagcagactg gaaaatagac ccgttggcga
    33241 cgggcgtcgg accgggaacc ggttgtgcac tggtcgcccc ctgtaccagc ggcgtggagg
    33301 gtatccaggc gcagccggtt agtgaaagcg ccaacaagct ggaaatggca taagtatgcg
    33361 cagcgttttt ttgcatggct atcatcttca aaaatcagta aaccggtgaa cctgcccacc
    33421 ggttaagcct tagagttgcg tcagtttttg cagcatctga tcggtggtgg acaccgcttt
    33481 actgttgatt tcgtaagcgc gttgcacctg aatcatattg accagttctt ccgccacgtt
    33541 gacgttagac gtttcaacat acccttgata cagcagtccc gcgccgttca ggcccggcgt
    33601 gctttcgttc ggtgcaccgg aggattgcgt ttcggtgtag aggttttcgc caatgctctc
    33661 cagtccggtg tcattcataa aggtggtgag attgagctgc ccaacctgaa ccggagctgc
    33721 ctggccttgt tgggttacgc tgaccacgcc atcacgaccg atggtgatac ttaacgcatt
    33781 cgccggaatg gtgatcgctg gctgcacctg aaaaccaccg gccgtcacca gctgcccgtt
    33841 ctgatccacc tggaaagagc cgtcacgggt ataggctgat gagccatctg gcaacatcac
    33901 ctggaaaaag ccctgccctt taatcgcgac gtctttactg ttattggttt gcgacaggtt
    33961 gccctggctg tgtaaacgtt ccgtggcgac agggcgtacc cccgtaccga tttgtaatcc
    34021 ggatggtaag gtggtttgtt cggaagactg tgcccccggc tggcgaatgg tttgataaag
    34081 tagatcttca aacaccgcgc gctgacgctt aaaaccgttg gtactaacgt ttgccaggtt
    34141 gttggcaatg acgtccatat tggtttgctg ggcgtcaagg cccgttttgg cgatccataa
    34201 tgaactgatc ataaaatgtc ctgtagtgga ttagtgacaa agtgcatatg tcttcttgcc
    34261 ggatgcggcg taaacgcctt atccggccta caagagctcg caaaatcgat aaattgcgat
    34321 tgcccccata gacccgataa acttgcgcat agggcaactt atacttgtca tgtatccttt
    34381 caattaactc atcgacagca gttggttggc acggcctgcg ttatcatcga cgctgctgat
    34441 caccttcatc tgcatttcaa aacgccgtgc gctggcaatc atgtcgctca ttgccgcaac
    34501 ggcattgacg ttactgcctt ccagaacccc cgacatcaca cgcaaggttg gatctgcctg
    34561 cagtaccggc ccacgcgtag cctggctttc tgcgcttaaa cgaaaaatgc catcgtcacc
    34621 gcgctggact tcgctgcccg tggctttcac cagcttcaga cgccccactg gcgcaaccgt
    34681 atttgccgga tcgcccggat tcagcgccga gattgtgcca tcggcagcaa tagtgatttc
    34741 cgccccttcc ggcacagcaa ttggccccgc ctcgcctacc accggatgtc cctgaattgt
    34801 cagttgcccg gtgggatcaa cctgaatgct gccattacgc gtataccctt cactgccgtc
    34861 agcggtctgc acgaccagcc aaccatcctg ctgcaacgca acgtccagcg ggcgcgaggt
    34921 gtaatccatc ttgccgggcg tcatgtctgc acccggtgtt gacgccgtta ccagcgtgcg
    34981 cgtgggcagt gaaagccctt ccaccggcac tgcgcgcaag gcgtttaact gcgcgcgaaa
    35041 accgggcgta gaggcattgg ccagattact ggcggttacc gcctgttgat tcagcgtctg
    35101 gctggctgct cccatcgcgg tataaattgc gtgatccatt gagctatccc gtcagcgatt
    35161 agcgtaagtt aaccagcgta ttgaggatct ggtcctgggt tttgatggtc tgggcgttag
    35221 actgatagtt acgctgggca acgatcatat tgaccagttc tttactgaga tcgacgttgg
    35281 acgcttccag cgcaccgttg gtcagggtgc caaagttgcc cgtcccggct gtccccaaca
    35341 gcgccacgcc agaagattgc gtagcggacc agacgttgtc gccttcggat gccagacctt
    35401 cgttgttggc aaagttcgcc agtacaatct gccccagcag ttgggtttgt tcgttggaat
    35461 agttgccgac aaccgtaccg tcatcattga tttgataact caccagatcg cccggtttgt
    35521 agccgttctg ggtggttgcc acaatgttgt tagcgccggt attttgctgc atggagttga
    35581 ggaagctcag gctaaacgtg gcgggatctg cgccgttaat tgcgccggtg gtaatatcct
    35641 ttgttggatc tgaggtcaga acgccattgg cattaaacac cagcgtcgtt gcagggttag
    35701 ctgtgcctgt tggatcactg ctatccaggg tgtaaacatc ccagttatta tccccggtct
    35761 tcacaaagta gacgctcatg tcatgagcat taccctgact atcgaaaaca gtcaccgaac
    35821 cttttttgtt atagctatcc gcattgctgg catcaaatgc gttaacagag ggaagcgaat
    35881 cactggaatt caggttgatc tgcatcgacg ccgtggtggt agttttcgct gccatcaggg
    35941 tattcggaat cgaaatattg gtcggattcg ccccttgctg aatagtcggc ggcgtaccgg
    36001 ttgccgggta acccgtcagc tgtaaacctt gcatattcac caggttacgg ttttcatcca
    36061 gcttaaattg tccgttacgg ctgtagaata ccgaaccatt gctgtctacc agacggaaaa
    36121 aaccgttctg gctgatagca acgtccagac cacgcccggt gttggtggtc gtgccatcgg
    36181 taaagtcctg agtgatacca gcaactttta cccccagtcc cactttcgaa ccggcaaaca
    36241 tatcggcaaa agaggccgtg cctgatttaa agccgtaggt ggcggagttg gcgatattgt
    36301 tgccaataac atcgaggttg gtggcggcag cgtttaatcc gctaaccgct tgagaaaagg
    36361 ccatgactga ctcctgaaat gtgaaggctt aaattatctg ccgtacttcg tcgagggtag
    36421 tggtgccgta agtgccaaga tccagcgtat taccgttgtt gccgcggatc accccctgca
    36481 ccagagcaaa ctgcagcggt tgggcaacca gttgtgtacc accgttactg gcgctaatcg
    36541 ctacattgta agaaccgttc ggcgcagtgc tgccgtcagt caacgtaccg tcccaggtga
    36601 aactgtggac tccggcagtc agttcaccga tatcaatggt acggacgacc gcgccgtttt
    36661 tatcggtgat ggtggccgtc actttgtctg ctgcctgttg caactcaaca ccaaacggcg
    36721 tggtcgtggt cacagcccct tcttcactgc cggttcccgc aagaactgtg gtaccgggga
    36781 tcatcacgcc gtgaccgata aggttactgg cctgtaacga ctgactgtta tcaatctgtc
    36841 cggaaataga tccgagcgtg gtattgagtt tttcaatccc actgaccgtg ctgatttgtg
    36901 ccaattgcga cgtcagctcg ttgttttcca ttggattggt cgggtcctgg tttttcagct
    36961 gcgccaccaa caaagtcaga aaactgcttt gtaaatctgc ggcgttgctg cccgtgagcg
    37021 aactactgct ggtggtactg acgccggtat tcgtcggatc ggtggtggtt accgcaatag
    37081 acatagcttt ctcctttatt gaccgagcgt aagggttttc agcatcatgc ttttcaccgt
    37141 gttgagcact tcaacattgg cctgataact gcgtgacgcc gacatggtgt taaccatctc
    37201 cccgacgaca tcaacgtttg gcattttcac gtagcccttt gcatccgcca gcggattacc
    37261 cggttcataa accagtttgt ccggggcctg actttctata acatcggcaa cctttacgcc
    37321 gcctgtcgca gcacctggtg cagcgttaac ctggaatacc acctgttttg cccgatatgg
    37381 ctgtccatcg ggaccggtca cgctatcagc attcgccaga ttactggccg ccacgttcag
    37441 acgctgggac tgggcagtta acgccgaccc ggcgatatca aaaatattca gcagtgccat
    37501 ccgttaattt ccgctctgta aaacgttcat catgccttta atttgcccgc tcaacgcgct
    37561 aaggctcatc tggtattgca ggctgttatc ggcaaactgg gtgcgttcgc gatccatatc
    37621 gacagtatta ccgtcaagcg aaggctggtc cggaatacgg tattgcagtt ctgcggaagg
    37681 aggcgtcagc gcctgcgccg gaatgtgttg cgttgaggtc atcgtcagag caaccacact
    37741 ggttgcatcc cgtccacgtt gcatgacttt tttaagttca ctggcaaaat cgatatcgcg
    37801 cgcctgataa ccaggggtat cggcattggc gatgtttgct gccagcactt cctgacgctg
    37861 ggcgcgcaga ttgagcgcct cttgttgaaa acgtaaggcg gcgtcgagct tatcgagcat
    37921 atctcctccg caggtatcaa aattctgcca tcagcttaaa tgcctttacg cgcgcgttat
    37981 cggcggaata aacgcaaaat gggtcgctat ttatgccgtt gatggtcatt gcggacaggt
    38041 acaattcacg ttgtagaaat ggctgggggc gaaaatgctg acaataaaac gtagcgtggc
    38101 gatcatcgcg atactcttca gtccgttaag tacggcgagc aatctcacat cgcaattgca
    38161 caactttttt agcgcccaac tcgcgggggt aagtgatgag gttcgtgttt ctattcgtac
    38221 agcgcccaat ctgctaccgc cgtgcgagca gccattgctt tcgatgagca ataattcccg
    38281 cctgtggggc aatgtgaatg tgttggcacg ctgcggtaac gacaaacgat atttacaggt
    38341 taatgtacag gccacaggaa attatgtggt tgccgcgatg cccattgtgc gtggaggaaa
    38401 gctggaagct ggcaatgtca aactgaaacg cggacggctg gataccttgc caccgcgtac
    38461 ggtgctggat atcaatcaac ttgttgatgc cgttagcctg cgcgatctat cacccgatca
    38521 acctatccag ttaacccact ttcgccaggc atggcgggta aaagcgggac aacgcgtcaa
    38581 cgttatcgcc agcggtgatg ggtttagcgc caacgcagaa ggtcaggcgc tgaacaatgc
    38641 agccgtcgca cagaatgcgc gggtgcgcat gatatcggga caagtggtca gcggcgttgt
    38701 tgatgcagat gggaatattc ttataaacct gtaagctgtt aaagattacc cgtcccttgc
    38761 cgataaataa gcaacacatg ataaaagcgc cctcaatgag gaataaacca tgagtattga
    38821 tcgcacttcg cctctgaagc cagtaagcac cgttcaaccg cgcgaaacca ctgacgcgcc
    38881 ggtaacaaac acccgagcgg caaaaacaac agcctccacc agcaccagtg tgacgttaag
    38941 cgacgcgcaa gcaaaactga tgcaacccgg cagcagtgat atcaatcttg aacgtgtcga
    39001 agcgttaaag ctggcgattc gtaacggtga actaaaaatg gacactggca aaattgccga
    39061 tgcgctgatc aacgaagcgc agcaagactt gcagagtaat tgatcgtatg acgcgtcttg
    39121 cagagatcct cgaccagatg tccgctgtgc ttaacgatct caaaacggta atggatcaag
    39181 agcagcaaca tctctctatg gggcagatca acggcagcca gttgcaatgg attacagaac
    39241 aaaaaagctc actgctggcg acgctggatt acctcgaaca gttacgcagg aaagaaccca
    39301 atacagcaaa tagcgttgat attagtcaac gctggcagga aattgctgtg aaaacgcagc
    39361 aactacgcca aatgaatcaa cataacggct ggttactgga aggacagatt gagcgcaatc
    39421 aacaggcgct ggaaatgttg aaaccgcatc aggaaccgac gctgtatggg gcgaacggtc
    39481 agacctcaac cccctatcgc ggcagtaaaa agatttcgat ctgaagatta tctccggcct
    39541 gcactgcagg ccggaatgta tcgttacacc gtccggcggg caaattcttt aactttgaag
    39601 cccagtactg ccagtgcagc gaagtacgcg gcaatccccg ccagcacgac cgccattaaa
    39661 cgcagtaaac gccagggcat ggtacccaat gaccactccg gcatgatatg taacatacct
    39721 aaaagcacgc cagacatcac cagtaccgcc accaccagac gcaacagaaa cgccatccag
    39781 ccgggttgcg gagtaaagat tttctgctta cgcaactgcc agtaaagcag cgaagcattc
    39841 agacacgccg ccagaccaat agaaagtgac agcccggcat gtttcaacgg accaataaac
    39901 gccaggttca tcaattgcgt taaaatcagc gtaacgatgg caattttcac tggcgtttta
    39961 atgtcctggc gggaataaaa gccaggagcc aacactttca ctacaatcag gccaatcaaa
    40021 cccaccgagt aggcaattaa cgcccgctgg gtcatcagcg catcaaaggc ggtaaattta
    40081 ccgtactgga acagcgaaac ggttaacgga ccggaaagaa tgcccaacgc aaccgcactt
    40141 ggcagcgcca acaggaaaca aagacgcagc ccccagtcca tcaaacggtt gtattcatca
    40201 tgattgccac tggcaaaact tttcgacagc gacggtagca aaatggtgcc aagcgccacg
    40261 cccagcacac cggacggaaa ctccattaag cggtcggcgt aatacatcca cgacaccgaa
    40321 ccggaagcaa gaaacgaggc aaaaatggtg ttgatgatta aggagatctg gctcacagag
    40381 acgccaagga ttgccggtcc catctgtttc accacacgca ttgctccggc atcgtggaag
    40441 ttaatgcgtg gcaaaaccag catgccgatc ttcttcagat gaggtagctg atacaccagc
    40501 tgcaggatgc cgccgaccgt aacagcccag gccagcgcca gcaccggtgg attaaagtac
    40561 ggcgcggcaa acagcgcaaa accaatcatg ctgatattga gcaatgtcgg ggcaaacgcc
    40621 ggaattgaga agcggttcca ggtattcaga atcgctccca ccagcgacgc cagggagatc
    40681 agcaagatat agggaaaggt tatctttagt agctggctgg tcagggcaaa tttgtcggca
    40741 gtgtcagcga agcctggcgc ggtcaccatg atcacccacg gtgcagcgag catgccagcg
    40801 accgtcacaa ccgccagcgc aagtgtcagc aggccagaaa cataagagac aaagacccgc
    40861 gtggcgtctt caccctgctt gcttttatat tctgccagaa tcggtacaaa tgcctgggaa
    40921 aatgcccctt cggcaaagat acggcgtaac aagttaggaa gtttaaaagc gacgaaaaag
    40981 gcgtcggttg ccatccctgc gccaaagatt ctggcgacaa ttgcgtctcg tgcgaagcca
    41041 agcacacgcg aaaacatggt catcgagctg acggcggcca gcgattttaa taaattcatc
    41101 ggtgttctaa tccagaccca cgggcaaaac gcctgcaagg caggcgctga aagaggcgaa
    41161 tagtctacct ggattatggt gaattgctac cgccagatgt tacagggttt attcactcat
    41221 cgcatcgcgc cagatcttgt caacgatacg ttgcgccagc acggcctgtt cgccggctgt
    41281 ttgcggaact gtctgatttt gcacgcattc aatgaagtgc cgcgcacagt cgacaaatcc
    41341 acgttgctca agcgtactct gccaaccagg aatcggttta tgcactacgc cctgcccgcg
    41401 ctcctcacgc cattcgcgca tatccgtaat gtcgatcagc gcaccatcag tcacggcctg
    41461 cacggtttca cgctgacttc cggcccggcg atgcatacag gtggtgatct gcaaaggacc
    41521 agccgaaaaa tggtgctcgg caaacagcat ttcgccggac tcattggtca gcaacgtacc
    41581 gctttcgaga gttgcattgc cgccagacaa ccacagcgcg gtatcaacca catgcaaata
    41641 atcatccagc aatgtgaaat aaagatcgtg tggcccgacg ctattggtac gatgtttatc
    41701 cattcttagc gaggacgcgg tggcgagttg cgtttttaac tcaccgtaga gtggtgcgaa
    41761 acgacggtta aaaccgacca tcaacgtcag ttttttccgc gccgccagtt ccaccagccg
    41821 ttcagcatcg cgcagatttt ctgccagcgg tttatcgaca cagacatgta cccccgcatt
    41881 gagtaacgta ctgaccacgc caaagtggct ggcggtgctg gaatgcacaa aaaccgcatc
    41941 gcaactggcg gcaaggctgg ataacgaatc agcataagga atgcgccagc tgtcacaaat
    42001 tggcagggct ttggcgcgcg taggcgacca ggcaccttgt aacgtccagt cagacgctgc
    42061 cgccagcacc ggtaaccacg ctttttgcgc gatgccgcct aaccccacta cgccgatacg
    42121 taattttttc actttaatct cccagatggg ccagcaacga atcaagacgc tgtttcagtt
    42181 ctgccacttc gatttccagg gcttcgacgc gggcctgtaa atcaccgtca accgcgttcg
    42241 acatatccgt taccgccggc ggattctcaa cctcaccact gaaaagatgc atgtagcggc
    42301 tttcgcgttt acccggttcg cgggccagac gcaccacaaa aggaccatct tcgcgattcg
    42361 ccagttgttc cagcgtcgac tccacttccg ccatatcgct gaattcatac attcgcgcgg
    42421 cgcggctgcg cagttcaccc ggcgtctggg caccacgcaa taacagcgtg gtgattaacg
    42481 ccacttctgc ggcgctcagt ttcagatcgc caaattctga attacaaaaa cgttgctcat
    42541 atttggtgac ccgattacca aaaccgctca ccgtgcgtag ataatgacgt ttgaccagat
    42601 tatccagctg ttcctgcact tcagattcac tcagattcat aaccggttca cggttcgttt
    42661 tctgattaca ggccgtgact acaccattta cggagagcgg gtattgctcc ggcgtggtca
    42721 cctgtttttc cagcaagcaa ccaatcacgc gggcttccag ggcggtcagt tgatatttca
    42781 tgagattctc cttagcggcc gggcgtccag tctggggtag ttaatgccgt cagtacgtga
    42841 tcgcgccatt gtccatcaat caacagatag tctttcgcat agccttcttt ttcaaaaccc
    42901 agtcgcgcca gtaaatcacc gctgcgttta ttgtgcggca tataattagc cataatgcga
    42961 tgaatatgtt gggtgcgctg catataacga atggctgcgc tcagagcttc aaacatgagt
    43021 cctttgccct gccatttttg cccaatcgaa taaccgagat agcaggcatg aaaagagccg
    43081 cgaacaacat tggaaaaatt ggcaacgcca ataatctctt tttcgtccgg gtcgaataag
    43141 ccaaagtaga aagctgaacc ttgtttatga aattcgttaa tcatccctag cctggcctgc
    43201 cagcctgatg gataacagtg gctttcgtcg cgcactggct cccagggctt gaggaaatgg
    43261 cgattctctg cgtaataatc cgccagacgc caggcatcac gatcatgcac cagacgcacg
    43321 accagtcggt ctgtggttaa gcgcactttt ggcacgttac tgcgatagcc aaacattcta
    43381 tacctactcc ttcccgtaac gtctttaata cgctgtaagt attactatac ctgcgcaacc
    43441 agaccctgtg aaaagtccag aatgccattt tctgcattat tcacatattt gataaaaact
    43501 ctctatcaaa gcgacgtttt gataaaaaaa tattgtcccc gaagtgatgg gaaaagtctt
    43561 agcggcaatg cagaatagaa agtgctcatc ttttatttcc cgggagggga aatgtcccgc
    43621 gtgtcgcagg cgaggaacct gggtaaatat ttcctgctca tcgataatat gctggtcgtg
    43681 ctggggttct ttgttgtctt cccgctgatc tctatccgct tcgttgatca aatgggctgg
    43741 gccgccgtca tggtcggtat tgccctcggt ctacgccagt ttattcagca aggtctgggt
    43801 attttcggcg gcgcaattgc cgaccgcttt ggtgccaaac cgatgattgt caccggtatg
    43861 ctgatgcgtg ccgccggatt cgccacaatg ggtatcgccc acgaaccgtg gctactgtgg
    43921 ttttcatgcc tgctttcggg actcggcggc acgttgtttg atcctccgcg ttcggcgctg
    43981 gtggtgaaac taatccgtcc acaacagcgt ggtcgttttt tctcgctgtt gatgatgcag
    44041 gacagtgccg gtgcggtcat tggcgcattg ttggggagct ggctgttgca atacgacttt
    44101 cgcctggtct gcgccacagg ggcagttttg tttgtgctgt gtgcggcgtt caatgcgtgg
    44161 ttgttaccag catggaaact ctccaccgta cgcacgcccg ttcgcgaagg catgacccgc
    44221 gtgatgcgcg acaagcgttt tgtcacctat gtcctgacgc tggcgggtta ctacatgctg
    44281 gctgtacaag tgatgctgat gctgccaatt atggtcaacg acgtggctgg cgcgccctct
    44341 gccgttaaat ggatgtatgc cattgaagcg tgtctgtcgt taacgttgct ctaccctatc
    44401 gcccgctgga gtgaaaagca ttttcgtctg gaacaccggt taatggctgg gctgttgata
    44461 atgtcattaa gcatgatgcc agtgggcatg gtcagcggcc tgcaacaact tttcaccctg
    44521 atttgtctgt tttatatcgg gtcgatcatt gccgagcctg cgcgtgaaac cttaagtgct
    44581 tcgctggcag acgcaagagc tcgcggcagc tatatgggat ttagccgtct gggtctggcg
    44641 attggcggcg ctattggtta tatcggtggc ggctggctgt ttgacctggg caaatcggcg
    44701 caccagccag agcttccgtg gatgatgctg ggcattattg gcatcttcac tttccttgcg
    44761 ctgggttggc agtttagcca gaaacgcgcc gcgcgtcgtt tgcttgaacg cgacgcctga
    44821 tttgatactc ccccctgact cctccatact gaaagagaac tgacagccaa atggaggagt
    44881 cacgtgaagc tatacattta cgatcactgc ccttactgcc tcaaagcccg catgattttc
    44941 ggcctgaaaa atatccccgt cgaattacat gttctgctca acgacgacgc agaaacaccc
    45001 acccggatgg tcggtcaaaa acaggttccc attctgcaaa aagatgacag ccgctatatg
    45061 ccagaaagca tggacatcgt tcactatgtc gataaactcg acggcaaacc gttactgacc
    45121 ggcaaacgtt cccctgccat tgaagagtgg ctgcgcaagg tcaatggcta cgccaacaaa
    45181 ctgctgttgc cgcgttttgc caaatcggca tttgatgagt tttctactcc tgccgcgcgc
    45241 aaatatttcg tcgacaagaa agaggccagc gcgggtaatt ttgccgacct gctggcccac
    45301 tctgacggtc tgattaagaa tatcagcgat gatttacgtg cgctggacaa actgatcgtc
    45361 aaaccgaacg ccgtgaatgg cgaactttcg gaagatgata ttcagctatt tccgctcctg
    45421 cgtaatctga cgctagtagc cggaatcaac tggccaagcc gcgttgctga ttaccgcgat
    45481 aatatggcga aacagacaca aatcaatttg ttatcatcaa tggcgattta atcctgaccc
    45541 gtcgcggcag cctgtattcg cgggttgccg ccgttttcag ttttttctgc tggcgcgtta
    45601 tcgctggtga cacatgctgc gttgtgtcag gatattgacg cagatttcat gtcgaggact
    45661 accatgaaca agtttttatt tgccgctgca ttgatcgtca gtggcctgct cgttggctgt
    45721 aatcaactca cccaatacac catcaccgaa caagaaatta accagtcgct tgcgaaacat
    45781 aataatttct caaaagatat cggtttaccc ggcgtggctg acgcccatat cgttctgaca
    45841 aacctgacca gccaaattgg tcgcgaagag ccgaataagg ttaccctaac cggagacgcc
    45901 aatctggaca tgaactccct gttcggtagc cagaaagcga ccatgaaact gaagctgaaa
    45961 gcgctgcccg tgtttgataa agaaaaaggc gcgatcttcc tgaaagagat ggaagtggtc
    46021 gatgcgacgg tacaaccgga aaaaatgcaa acggtgatgc aaacgttgct tccctattta
    46081 aaccaggcat tacgcaatta ctttaaccag caacctgctt acgtcctgcg cgaagatggc
    46141 agccagggcg aagcaatggc gaagaaactg gcgaaaggca ttgaagtgaa gccaggcgaa
    46201 attgtcattc cgtttactga ttaatcacga gggcgcattc gcgcccttta tttttcgtgc
    46261 aaaggaaaac gtttccgctt atcctttgtg tccggcaaaa acatcccttc agccggagca
    46321 tagagattaa tgactgcacc atcccaggtt ttaaagatcc gccgcccaga cgactggcac
    46381 cttcacctcc gcgatggcga catgttaaaa actgtcgtgc cgtataccag cgaaatttat
    46441 ggacgggcta tcgtaatgcc caatctggct ccgcccgtga ccaccgtaga ggctgccgtg
    46501 gcgtatcgcc agcgtattct tgacgccgta cctgccgggc acgatttcac cccgctgatg
    46561 acctgttatt taacagattc gctggatcct aatgagctgg agcgcggatt taacgaaggc
    46621 gtgttcaccg ctgcaaaact ttatccggca aatgcaacca ctaactccag ccacggcgtt
    46681 acgtcagttg acgcaatcat gccggtactt gagcgcatgg aaaaaatcgg tatgccgcta
    46741 ctggtgcatg gtgaagtaac acatgcagat atcgacattt ttgatcgtga agcgcgcttt
    46801 atagaaagcg tgatggaacc gctgcgccag cgcctgaccg cgctgaaagt cgtttttgag
    46861 catatcacca ccaaagacgc tgccgactat gtccgtgacg gaaatgaacg gctggctgcc
    46921 accatcactc cgcagcatct gatgtttaac cgcaaccata tgctggttgg tggtgtgcgt
    46981 ccgcacctgt attgtctacc catcctcaaa cgcaatatcc accaacaggc attgcgtgaa
    47041 ctggtcgcca gcggttttaa tcgtgtattc ctcggaacgg attctgcgcc acatgcacgt
    47101 catcgcaaag agagcagctg cggctgcgcg ggctgtttca acgccccaac cgcgctgggc
    47161 agttacgcta ccgtctttga agagatgaat gctttgcagc actttgaagc attctgttct
    47221 gtaaacggcc cgcagttcta tggcttgccg gtcaacgaca cattcatcga actggtacgt
    47281 gaagagcaac aggttgctga aagcatcgca ctgactgatg acacgctggt gccattcctc
    47341 gccggagaaa cggtacgctg gtccgttaaa taataaaaat cgtagcttcc tgttgtcatt
    47401 aggttatttt acctgtataa ataaccagta tattcaacag ggggctatta tgcgaattga
    47461 agtcaccata gcgaaaactt ctccattgcc agctggggct attgacgccc tggctggcga
    47521 actttcccgc cgtattcagt atgcgtttcc tgataatgaa ggccacgtat cggtacgtta
    47581 tgccgcagca aataatttat cggttattgg cgcgacaaaa gaagataaac agcgcattag
    47641 cgaaattctc caggagacgt gggaaagcgc cgatgactgg tttgtcagcg aataatatgc
    47701 agtgattttt gtttttgccg ggtcgccccg gcttttttat tttacttgcg aattgtgagt
    47761 acaaaatttc tacacttact caaaataatt gcacaatatg ctaaaaaaat atgaatgaca
    47821 tgctgtttta ttgttcatat aaatcttaaa agcagaaatt tatctgttcc ccctttaaaa
    47881 attcggtgaa tacccttact tattggtata ctgaagttgc ttcagataaa aacgcattga
    47941 acctcgaata acgttgtcta gtaacacgaa ttagggggcc atgatggaaa aaaataatga
    48001 agtcattcag actcatccgc tcgtagggtg ggacatcagc accgttgata gctatgatgc
    48061 gctgatgttg cgtttgcact accagacccc aaataagtcc gagcaggaag ggactgaagt
    48121 tggtcagacg ctctggttaa ccactgatgt tgccagacaa tttatttcga tattagaagc
    48181 aggaatcgcc aaaattgaat ccggtgattt ccaggtaaac gagtatcggc gtcattaaca
    48241 tgacatgacc atccacccaa aaggcacctc accggtgcct ttaccatttc tgggttgtat
    48301 atctgcattc agttaattac tctgcttaaa ccatgagagc agagagaaaa aaatgaaata
    48361 cgatctcatc attattggca gcggttccgt aggcgctgcc gccgggtatt atgcaacccg
    48421 cgccggttta aacgtgctaa tgaccgacgc ccatatgcca ccgcatcaac acggcagcca
    48481 ccacggcgat acgcgattaa ttcgccatgc ttatggtgaa ggcgaaaagt atgtcccgct
    48541 ggtcctccac gcgcaaatgc tgtgggatga actttcccgc cacaacgaag atgatcccat
    48601 ttttgtacgc tctggtgtca ttaacctcgg tccggctgac tccgcatttc tcgccaacgt
    48661 cgcccacagc gccgaccagt ggcaactcaa cgttgaaaag ctcgacgcgc aagggattat
    48721 ggcccgctgg ccagaaatac gcgtcccgga caactacatc ggtttatttg aaactgattc
    48781 cggttttttg cgcagcgaac tggcgattaa aacctggatc caactggcga aggaagcggg
    48841 ctgtgcgcag ctgttcaact gcccggtcac cgcaattcgt catgacgatg atggcgtaac
    48901 tattgaaacg gcagacggtg agtatcaggc gaaaaaagcg attgtctgcg cgggaacatg
    48961 ggtaaaagac ctactcccgg agctgcctgt ccagcccgta cgcaaagtat ttgcctggta
    49021 tcaggccgat ggccgctata gcgtgaagaa taaattcccg gcatttaccg gtgagctgcc
    49081 caatggcgat caatattatg gttttccggc agaaaacgac gcgttgaaga ttggcaaaca
    49141 taacggaggc caggttatcc attcagcgga tgaacgtgtt ccgtttgcgg aagtggccag
    49201 cgatggttcg gaagccttcc cgttcttgcg caatgtgttg ccgggtatcg gttgctgcct
    49261 gtacggcgct gcctgcacct atgataattc gcctgacgaa gattttatta tcgataccct
    49321 acccggccac gataatacac tgctcattac cggcctgagt gggcacggtt ttaaatttgc
    49381 gtcagtttta ggggaaatag ctgccgattt tgcgcaagac aaaaaaagcg attttgattt
    49441 gacgccattc aggctttccc gcttccaata atcatcatta cggcctccag aatgaggccg
    49501 tttttacagg agtatttaat gcgtcgactg ttgcactatc tcatcaataa tattcgcgag
    49561 catctgatgc tttatctttt tctctgggga ttgttggcaa ttatggatct gatctatgtg
    49621 ttttattttt agttttccgc actgacataa actgacaaat atttaatctc cctttcattt
    49681 agcgtgaaaa attgaatgag a
//
LOCUS       DAFGPF010000022        47920 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFGPF010000022 DAFGPF010000000
VERSION     DAFGPF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47920
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.022"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..264)
                     /locus_tag="LSX49_001506"
     CDS             complement(<1..264)
                     /locus_tag="LSX49_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7167936.1"
                     /translation="MSENDIIIRTHYESPLRMHIDSDILTPSSEPISQFARQLITLLD
                     TSDLSSMLSYCVTQEFTVSCRKISHNCYSTALFIINFATSPIHA"
     gene            788..2716
                     /gene="thrS"
                     /locus_tag="LSX49_001507"
     CDS             788..2716
                     /gene="thrS"
                     /locus_tag="LSX49_001507"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBL7167937.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSDYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            2720..3262
                     /gene="infC"
                     /locus_tag="LSX49_001508"
     CDS             2720..3262
                     /gene="infC"
                     /locus_tag="LSX49_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBL7167938.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            3359..3556
                     /gene="rpmI"
                     /locus_tag="LSX49_001509"
     CDS             3359..3556
                     /gene="rpmI"
                     /locus_tag="LSX49_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBL7167939.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            3609..3965
                     /gene="rplT"
                     /locus_tag="LSX49_001510"
     CDS             3609..3965
                     /gene="rplT"
                     /locus_tag="LSX49_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBL7167940.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     misc_feature    4082..4206
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            4088..4132
                     /gene="pheM"
                     /locus_tag="LSX49_001511"
     CDS             4088..4132
                     /gene="pheM"
                     /locus_tag="LSX49_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HBL7167941.1"
                     /translation="MNAAIFRFFFYFST"
     gene            4416..5399
                     /gene="pheS"
                     /locus_tag="LSX49_001512"
     CDS             4416..5399
                     /gene="pheS"
                     /locus_tag="LSX49_001512"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBL7167942.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     gene            5414..7801
                     /gene="pheT"
                     /locus_tag="LSX49_001513"
     CDS             5414..7801
                     /gene="pheT"
                     /locus_tag="LSX49_001513"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBL7167943.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHNGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVEPEIVPVGATIDDTLPIAVEAPDACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGIHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            7806..8105
                     /gene="ihfA"
                     /locus_tag="LSX49_001514"
     CDS             7806..8105
                     /gene="ihfA"
                     /locus_tag="LSX49_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HBL7167944.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE"
     gene            8206..9186
                     /gene="btuC"
                     /locus_tag="LSX49_001515"
     CDS             8206..9186
                     /gene="btuC"
                     /locus_tag="LSX49_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HBL7167945.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     TPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPVNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR"
     gene            9249..9800
                     /gene="btuE"
                     /locus_tag="LSX49_001516"
     CDS             9249..9800
                     /gene="btuE"
                     /locus_tag="LSX49_001516"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HBL7167946.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKYAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWADRGFVVLGFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGLVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            9800..10549
                     /gene="btuD"
                     /locus_tag="LSX49_001517"
     CDS             9800..10549
                     /gene="btuD"
                     /locus_tag="LSX49_001517"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HBL7167947.1"
                     /translation="MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQNALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPANLAQAYGMNFRRLDIEGHRMLISTI"
     gene            10627..11091
                     /locus_tag="LSX49_001518"
     CDS             10627..11091
                     /locus_tag="LSX49_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL7167948.1"
                     /translation="MRFCLILITALFLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI"
     gene            11339..12052
                     /gene="ydiV"
                     /locus_tag="LSX49_001519"
     CDS             11339..12052
                     /gene="ydiV"
                     /locus_tag="LSX49_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HBL7167949.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQDLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLDRDNFAG
                     ELLKYPFIELLINENYPHFNEGKDNRDLLSLSQMYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTPEILAQIIPFDFHAL
                     QGCLWPAVPINQITTLVQR"
     gene            12115..13551
                     /locus_tag="LSX49_001520"
     CDS             12115..13551
                     /locus_tag="LSX49_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HBL7167950.1"
                     /translation="MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIP
                     SSLFKNGAGVWGGENLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TVEPGAMLMRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWPHLADDEDKYRLW
                     FTDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDGLNEALDSYQQVLLTHYGQRMRQKLG
                     FMTELKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRGRLQQDEITDNERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRDDDYVSRPPDWGKRLEVSCSS"
     gene            complement(13555..13746)
                     /gene="hemP"
                     /locus_tag="LSX49_001521"
     CDS             complement(13555..13746)
                     /gene="hemP"
                     /locus_tag="LSX49_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HBL7167951.1"
                     /translation="MRYTDSRKLTPETDANHKTASPQPIRRITSQTLLGPDGKLIIDH
                     DGQEYLLRKTQAGKLLLTK"
     gene            complement(13878..14924)
                     /gene="aroH"
                     /locus_tag="LSX49_001522"
     CDS             complement(13878..14924)
                     /gene="aroH"
                     /locus_tag="LSX49_001522"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HBL7167952.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            complement(15081..15914)
                     /gene="ppsR"
                     /locus_tag="LSX49_001523"
     CDS             complement(15081..15914)
                     /gene="ppsR"
                     /locus_tag="LSX49_001523"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HBL7167953.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     Y"
     gene            16247..18625
                     /gene="ppsA"
                     /locus_tag="LSX49_001524"
     CDS             16247..18625
                     /gene="ppsA"
                     /locus_tag="LSX49_001524"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HBL7167954.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGVDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(18682..20328)
                     /gene="fadK"
                     /locus_tag="LSX49_001525"
     CDS             complement(18682..20328)
                     /gene="fadK"
                     /locus_tag="LSX49_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HBL7167955.1"
                     /translation="MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVV
                     DNHGATYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKTGAVS
                     VPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
                     APATSSLSLSQILADNTPLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASER
                     AYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQ
                     RCTCMLGATPFVYDLLNLLEKQPADLSALRFFLCGGTTIPKKVARECQQRGIKLLSVY
                     GSTESSPHAVVNLDDPLPRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNV
                     FMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVE
                     DILLQHPKIHDACVVAMPDERLGERSCAYVVLKAPHHSLSLEEVVAFFSRKRVAKYKY
                     PEHIVVIEKLPRTVSGKIQKFLLRKDIMRRLTQDVCEEIE"
     gene            complement(20385..20678)
                     /locus_tag="LSX49_001526"
     CDS             complement(20385..20678)
                     /locus_tag="LSX49_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HBL7167956.1"
                     /translation="MSQNATVNVDIKLGVDKFHVDEGHPHIILAANPDINEFRKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWQYPAGTFGIEFRYG"
     gene            complement(20675..21964)
                     /locus_tag="LSX49_001527"
     CDS             complement(20675..21964)
                     /locus_tag="LSX49_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL7167957.1"
                     /translation="MSDDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAASAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVSASNPHHYAVGVKEVIGLTPEQINDRFNVTGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSVSLGLVCGLGDIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SAHMVPEGGLAMVPQLVNDGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KERADFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNDMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(22019..22957)
                     /locus_tag="LSX49_001528"
     CDS             complement(22019..22957)
                     /locus_tag="LSX49_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HBL7167958.1"
                     /translation="MSQLNSVWVFSDNPERYAELFGSAQQWGQQVYAIVQNTEQAQAV
                     MPYGPKCIYVLEQNDALQRTENYAESIAALLKDKHPAMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIVDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTRDISH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLNR"
     gene            complement(22977..23741)
                     /locus_tag="LSX49_001529"
     CDS             complement(22977..23741)
                     /locus_tag="LSX49_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HBL7167959.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHSLYMVQDAQLEHALPLDTAKALA
                     TAVEKIGFDLLIFGEGSGDLYAQQVGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIGWSQSAPLAEL
                     TGIRVPPQTERKHIILDNDSPEAIAELAEHLKKALN"
     gene            24057..24968
                     /locus_tag="LSX49_001530"
     CDS             24057..24968
                     /locus_tag="LSX49_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL7167960.1"
                     /translation="MYQRCFDNASETLFVAGKTPRLSRFAFSDDPKWESGHHVHDNET
                     ELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHAVASDVNDPATTCTCALYGFQFQ
                     GAEENQLLQPHSCPVIAAGQGKEVIKTLFNELSVILPQSKNSQTSSLWDAFAYTLAIL
                     YYENFKNAYRSEQGYIKKDVLIKDILFYLNNNYREKITLEQLSKKFRASVSYICHEFT
                     KEYRISPINYVIQRRMTEAKWSLTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPS
                     DYRRQFKNCFAEQEILSEFPQPVSLAG"
     gene            complement(25011..26162)
                     /locus_tag="LSX49_001531"
     CDS             complement(25011..26162)
                     /locus_tag="LSX49_001531"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBL7167961.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(26176..27771)
                     /locus_tag="LSX49_001532"
     CDS             complement(26176..27771)
                     /locus_tag="LSX49_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HBL7167962.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SDLAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIVFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
     gene            complement(27918..28676)
                     /gene="aroD"
                     /locus_tag="LSX49_001533"
     CDS             complement(27918..28676)
                     /gene="aroD"
                     /locus_tag="LSX49_001533"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBL7167963.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDI
                     LEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(28707..29573)
                     /gene="ydiB"
                     /locus_tag="LSX49_001534"
     CDS             complement(28707..29573)
                     /gene="ydiB"
                     /locus_tag="LSX49_001534"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HBL7167964.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEV
                     DNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMEPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(29585..30850)
                     /locus_tag="LSX49_001535"
     CDS             complement(29585..30850)
                     /locus_tag="LSX49_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7167965.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMTSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYCLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVANELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGEHKFSTRLNTIKHRG"
     gene            complement(31077..32291)
                     /locus_tag="LSX49_001536"
     CDS             complement(31077..32291)
                     /locus_tag="LSX49_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7167966.1"
                     /translation="MKNPYYPTALGLYFNYLVHGMGVILMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILHTNNIIIAYVFG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGRHLPVIKKTTSSTEHRCSIIDLASYSLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFISFIALLTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFILALFIGLRSRKETR
                     HHTLKENIAPGG"
     gene            complement(32391..32747)
                     /locus_tag="LSX49_001537"
     CDS             complement(32391..32747)
                     /locus_tag="LSX49_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707588.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HBL7167967.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGNSESWRQWENGKCAIP
                     DYVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQQVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
     gene            complement(32883..32990)
                     /gene="rprA"
                     /locus_tag="LSX49_001538"
     ncRNA           complement(32883..32990)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="LSX49_001538"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(33176..34288)
                     /gene="ydiK"
                     /locus_tag="LSX49_001539"
     CDS             complement(33176..34288)
                     /gene="ydiK"
                     /locus_tag="LSX49_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HBL7167968.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKSNK"
     gene            34502..37558
                     /locus_tag="LSX49_001540"
     CDS             34502..37558
                     /locus_tag="LSX49_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBL7167969.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDKEMLGLNIVEFAGDDEALIDERVNALCVRLDELIASQQAGVIGWQVCREL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGFDAPMMKVDAVKRGTFDRQIPI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLEALNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLTLGEERGEFNVLLANEWLASALESQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEAKNHKNSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            37555..37965
                     /gene="menI"
                     /locus_tag="LSX49_001541"
     CDS             37555..37965
                     /gene="menI"
                     /locus_tag="LSX49_001541"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HBL7167970.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGLLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSVREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            38065..38253
                     /locus_tag="LSX49_001542"
     CDS             38065..38253
                     /locus_tag="LSX49_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HBL7167971.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            38802..39170
                     /gene="sufA"
                     /locus_tag="LSX49_001543"
     CDS             38802..39170
                     /gene="sufA"
                     /locus_tag="LSX49_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HBL7167972.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMIGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            39179..40666
                     /gene="sufB"
                     /locus_tag="LSX49_001544"
     CDS             39179..40666
                     /gene="sufB"
                     /locus_tag="LSX49_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBL7167973.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYHAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDN
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTVISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            40676..41422
                     /gene="sufC"
                     /locus_tag="LSX49_001545"
     CDS             40676..41422
                     /gene="sufC"
                     /locus_tag="LSX49_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBL7167974.1"
                     /translation="MLSIKDLHVSVEDKAILRGLSLDVRPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTSGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ"
     gene            41397..42668
                     /gene="sufD"
                     /locus_tag="LSX49_001546"
     CDS             41397..42668
                     /gene="sufD"
                     /locus_tag="LSX49_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBL7167975.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGAKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLDGLTNSQFVCIAGEISPQQRDALALTLDAVRLVFVDGRYVPALSDATE
                     GSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPTKPLLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPLSHHFAHNDLLLADDATAFSHSFLLGGAVLRHNTSTQLNGENSTVRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQMFYLRSRGINQQDAQQMIIYA
                     FAAELTEALCDEGLKQQVMARIGQRLPGGAR"
     gene            42665..43885
                     /gene="sufS"
                     /locus_tag="LSX49_001547"
     CDS             42665..43885
                     /gene="sufS"
                     /locus_tag="LSX49_001547"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HBL7167976.1"
                     /translation="MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEA
                     EFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVA
                     NSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTL
                     FDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCD
                     FYVFSGHKLYGPTGIGVLYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEA
                     GTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALAQLESVPDLTLYGPQNRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVD
                     RLVTGLQRIHRLLG"
     gene            43898..44314
                     /gene="sufE"
                     /locus_tag="LSX49_001548"
     CDS             43898..44314
                     /gene="sufE"
                     /locus_tag="LSX49_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HBL7167977.1"
                     /translation="MAVLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDKSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            44462..45466
                     /gene="ldtE"
                     /locus_tag="LSX49_001549"
     CDS             44462..45466
                     /gene="ldtE"
                     /locus_tag="LSX49_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HBL7167978.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVAVSSGATPAASNAPSVESAQNGEPEQGNMLRATQ
                     "
     gene            complement(45529..45765)
                     /gene="lpp"
                     /locus_tag="LSX49_001550"
     CDS             complement(45529..45765)
                     /gene="lpp"
                     /locus_tag="LSX49_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HBL7167979.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
     gene            complement(46076..47488)
                     /gene="pykF"
                     /locus_tag="LSX49_001551"
     CDS             complement(46076..47488)
                     /gene="pykF"
                     /locus_tag="LSX49_001551"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HBL7167980.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVV
                     MVSGALVPSGTTNTASVHVL"
BASE COUNT        12126 a        11562 c        12359 g        11873 t
ORIGIN      
        1 tgcatggatg ggtgaagtgg caaagttaat gataaaaagg gcagtggaat aacaattgtg
       61 tgatattttt cgacagctta cggtaaattc ctgagtaaca cagtatgaca gcatcgaact
      121 taaatcagag gtatcaagta gggtgatgag ctggcgcgca aattgactaa taggctctga
      181 tgaaggcgtt agtatgtcgc tatcgatgtg cattctaaga ggagactcat aatgagttct
      241 gataatgata tcgttttcac tcataatcta ttcgccttat atatgtctgg agattttgag
      301 gatgatgatt aattattatc gccagaacga aatgcgcacg aaaaattgct ataagaattg
      361 tgtcactttt atcattgcga tatgaccact tcgtcactga atctcatgat cgtttaaata
      421 ccaccgccaa ataacgcaac gaactttgct ggattcagtt tatgctgctg taaatccgct
      481 cgtagtaaac ctttcagaca ctctgtgatg atatcagtgg ttctttaagc gttttgctgg
      541 tgtactcact acaaacgaat tgcgaatcga atcaatgtga aacggaaagg tacaatctcc
      601 ctttttttag tgttaacatc gttcaaccgg gtggaaggtg agaggttaat gtctttcatt
      661 tgtgtacctg attgcgaacc aatttagcat ttgttggcta gatggtttcg caatgaactg
      721 ttaataaaca aatttttctt tgtatgtgat ctttcgtgtg ggtcaccact gcaaataagg
      781 atatataatg cctgttataa ctcttcctga tggcagccaa cgccattacg accacgctgt
      841 aagccccatg gatgttgcgc tggacattgg tccaggtctg gcgaaagcct gtatcgcagg
      901 gcgcgttaat ggcgaactgg ttgatgcttg cgatctgatt gaaaacgacg cacaactgtc
      961 gatcattacc gccaaagacg aagaaggtct ggagatcatt cgtcactcct gtgcgcacct
     1021 gttagggcac gcgattaaac aactttggcc gcataccaaa atggcaatcg gcccggttat
     1081 tgacaacggt ttttattacg acgttgatct tgaccgcacg ttaacccagg aagatgtcga
     1141 agcactcgag aagcggatgc atgagcttgc tgagaaaaac tacgacgtca ttaagaagaa
     1201 agtcagctgg catgaagcgc gtgaaacttt cgccaaccgt ggggagagct acaaagtctc
     1261 cattcttgac gaaaacatcg cccatgatga caagccaggt ctgtacttcc atgaagaata
     1321 tgtcgatatg tgccgcggtc cgcacgtacc gaacatgcgt ttctgccatc atttcaaact
     1381 aatgaaaacg gcaggggctt actggcgtgg cgacagcaac aacaaaatgt tgcaacgtat
     1441 ttacggtacg gcgtgggcag acaaaaaagc gcttaacgct tacctgcaac gcctggaaga
     1501 agccgcgaaa cgcgaccacc gtaaaatcgg taaacagctc gacctgtacc atatgcagga
     1561 agaagcgccg ggtatggtat tctggcacaa cgacggctgg accatcttcc gtgaactgga
     1621 agtgtttgtt cgttctaaac tgaaagagta ccagtatcag gaagttaaag gtccgttcat
     1681 gatggaccgt gtcctgtggg aaaaaaccgg tcactgggac aactacaaag atgcaatgtt
     1741 caccacgtct tctgagaacc gtgaatactg cattaagccg atgaactgcc cggggcacgt
     1801 acaaattttc aaccaggggc tgaagtctta tcgcgatctg ccgctgcgta tggccgagtt
     1861 tggtagctgc caccgtaacg agccgtcagg ttcgctgcat ggcctgatgc gcgtgcgtgg
     1921 ttttacccag gatgacgcgc atatcttctg tactgaagaa caaattcgcg atgaagttaa
     1981 cggatgtatc cgtttagtct atgatatgta cagcactttt ggcttcgaga agatcgtcgt
     2041 caaactctcc actcgtcctg aaaaacgtat tggcagcgac gaaatgtggg atcgtgctga
     2101 ggcggacctg gcggttgcgc tggaagaaaa caacatcccg tttgaatatc aactgggtga
     2161 aggcgctttc tacggtccga aaattgaatt taccctgtat gactgcctcg atcgtgcatg
     2221 gcagtgcggt acagtacagc tggacttctc cttgccgtct cgtctgagcg cctcctatgt
     2281 gggcgaagac aacgagcgta aggttccggt aatgattcac cgcgcaattc tggggtcgat
     2341 ggaacgtttc atcggtatcc tgaccgaaga attcgctggt ttcttcccga cctggcttgc
     2401 gccggttcag gttgttatca tgaatattac cgattcacag tctgattacg ttaacgaatt
     2461 gacgcaaaaa ctatcaaatg cgggcattcg tgttaaagca gacttgagaa atgagaagat
     2521 tggctttaaa atccgcgagc acactttgcg tcgcgtccca tatatgctgg tctgtggtga
     2581 taaagaggtg gaatcaggca aagttgccgt tcgcacccgc cgtggtaaag acctgggaag
     2641 catggacgta aatgaagtga tcgagaagct gcaacaagag attcgcagcc gcagtcttaa
     2701 acaattggag gaataaggta ttaaaggcgg aaaacgagtt caaacggcgc gccctaaccg
     2761 tatcaatggc gaaattcgcg cccaggaagt tcgcttaaca ggtctggaag gcgagcagct
     2821 tggtattgtg agtctgagag aagctctgga gaaagcagaa gaagccggag tagacttagt
     2881 cgagatcagc cctaacgccg agccgccggt ttgtcgtata atggattacg gcaaattcct
     2941 ctatgaaaag agtaagtctt ctaaggaaca gaagaaaaag caaaaagtta tccaggttaa
     3001 ggaaattaaa ttccgtcctg gtacagatga aggcgactat caggtaaaac tccgcagcct
     3061 gattcgcttt ctcgaagagg gtgataaagc caaaatcacg ctgcgtttcc gcggtcgtga
     3121 gatggcgcac cagcaaatcg gtatggaagt gcttaatcgc gtgaaagacg atttgcaaga
     3181 actggcagtg gtcgaatcct tcccaacgaa gatcgaaggc cgccagatga tcatggtgct
     3241 cgctcctaag aagaaacagt aaggccttca agtagcactg tctgtggagc ctttgggctt
     3301 cacaggcatt gttcgccttt gtttcgttta ttaacaatgc gaagtggaag ttattaaaat
     3361 gccaaaaatt aagaccgtac gcggtgctgc taagcgcttc aaaaaaaccg gtaaaggtgg
     3421 ttttaagcac aagcacgcta acctgcgtca cattctgacc aaaaaagcga ccaaacgtaa
     3481 acgtcacctg cgtccgaaag ccatggtttc caaaggcgat ctgggcctgg taatcgcgtg
     3541 cctgccgtac gcataagccg ttaacgtttt taacttttta attagaatat agatacagga
     3601 gagcacatat ggctcgcgta aaacgtggtg ttattgcacg cgcacgtcac aagaaaattt
     3661 tgaaacaagc taaaggctac tacggtgcgc gttctcgcgt ataccgcgtt gccttccagg
     3721 ctgttatcaa agctggtcag tatgcttacc gcgaccgtcg tcaacgtaag cgtcagttcc
     3781 gtcaactgtg gattgcgcgt atcaacgcag cagcacgtca gaatggtatt tcttacagca
     3841 aattcatcaa tggcctgaaa aaagcctctg ttgaaatcga ccgtaagatc ctggctgata
     3901 tcgcagtatt cgacaaagta gcgttcaccg ctctggttga aaaagcgaaa gcagctctgg
     3961 cataagccag ttgaaagagg gagctagtct ccctcttttc gtttcaacgc catcaaaaca
     4021 ttgactttta tcgccgtagc cttttcaata aaggtctttt gaagagtacc aaaaggtaac
     4081 gcaagcaatg aatgctgcta ttttccgctt ctttttttac tttagcacct gactccagga
     4141 ggctagcgcg tgagaagaga aacggaaaac agcgcctgaa agcctcccag tggaggcttt
     4201 ttttgtatgc gcgttttgaa aaataaaaag cctgtctcat caggcgtaat tgtcgcagcc
     4261 agtctggaca cggccagcgc ggagaaaccg gaccgtactt aagtacgtga ggatttcgag
     4321 cactgcccgg gaccaaaatg gcaagtaaaa tagcctgatg ggatgggctc taagtccaac
     4381 gaaccagtgt caccactgac acaatgagga aaaacatgtc acatctcgca gaactggttg
     4441 ccagtgcgaa ggcggccatt agccaggcgt cagatgttgc cgcgttagat aatgtgcgcg
     4501 tcgaatattt gggtaaaaaa gggcacttaa cccttcagat gacgaccctg cgtgagctgc
     4561 cgccagaaga gcgtccggca gctggtgcgg ttatcaatga agcgaaagag caggttcagc
     4621 aggcgctgaa tgcgcgtaaa gcggaactgg aaagcgcagc actgaatgcg cgtctggcgg
     4681 cggaaacgat tgatgtctcc ctgcctggtc gtcgcattga aaacggcggg ctgcatccgg
     4741 ttacccgtac catcgaccgt atcgaaagtt tcttcggtga gcttggcttt accgtggcaa
     4801 ccgggccgga aatcgaagac gattatcata acttcgatgc tctgaacatt cctggtcacc
     4861 accctgcgcg cgctgaccac gacactttct ggtttgacgc tacccgcctg ctgcgtaccc
     4921 agacctctgg cgtacagatc cgcaccatga aagcccagca gccaccgatt cgtatcatcg
     4981 cgcctggccg cgtttatcgt aacgactacg accagactca cacgccgatg ttccatcaga
     5041 tggaaggtct gattgttgat accaacatca gctttactaa cctgaaaggc acgctgcacg
     5101 acttcctgcg taacttcttt gaggaagatt tgcagatccg cttccgtcct tcctacttcc
     5161 cgtttaccga accttctgca gaagtggacg tcatgggtaa aaacggaaaa tggctggaag
     5221 tactgggctg cgggatggtg catccgaacg tgctgcgtaa cgttggcatc gacccggaag
     5281 tttactctgg tttcgccttc gggatgggga tggagcgtct gactatgttg cgctacggcg
     5341 tcaccgacct gcgttcattc tttgaaaacg atctgcgttt cctcaaacag tttaaataag
     5401 gcaggaatag attatgaaat tcagtgaact gtggttacgc gaatgggtga acccggcgat
     5461 tgatagcgac gcgctggcaa atcaaatcac gatggcgggc ctggaagttg atggtgtaga
     5521 accggttgcc ggtagcttcc acggcgtggt tgtgggtgaa gtggttgagt gtgcgcagca
     5581 tccgaacgct gacaaactgc gtgtgacaaa agtgaatgtc ggcggcgatc gcctgctgga
     5641 catcgtctgc ggtgcgccaa actgccgtca gggcctgcgt gtggcggtag cgaccattgg
     5701 tgctgttctg ccgggtgatt tcaaaattaa agccgcgaaa ctgcgtggcg aaccgtctga
     5761 agggatgctg tgctccttct ctgagctggg aatttctgac gatcataacg gcattatcga
     5821 gctgcctgcg gatgcgccga ttggcaccga catccgcgaa tacctgaaac tcgatgacaa
     5881 caccatcgaa atcagcgtga caccaaaccg tgccgactgc ttaggtatca ttggtgttgc
     5941 gcgcgacgtt gccgtgttga accagctgcc gctggttgaa ccggaaatcg ttccggttgg
     6001 tgcgaccatc gacgacacgc tgccgattgc agtagaagcg ccggatgcct gcccgcgcta
     6061 tcttggccgt gttgtaaaag gcattaacgt taaagcgcca actccgctgt ggatgaaaga
     6121 aaaactgcgt cgttgcggga tccgttctat cgatgcagtt gttgacgtca ccaactatgt
     6181 gctgctcgaa ctgggccagc cgatgcacgc tttcgataaa gatcgcattg aaggcggcat
     6241 tgtggtgcgg atggcaaaag agggtgaaac gctggtattg ctcgacggta ctgaagcgaa
     6301 gctgaatgct gacaccctgg tcatcgccga ccacaacaag gcgctggcga tgggcggcat
     6361 atttggtggc gaacactctg gcgtgaatga cgaaacgcaa aacgttctgc tggaatgcgc
     6421 tttcttcagc ccgctgtcta tcaccggtcg tgctcgtcgt catggcctgc atactgatgc
     6481 gtctcaccgt tatgagcgtg gcgttgatcc ggcactgcag cacaaagcga tggaacgtgc
     6541 gacccgtctg ctgatcgaca tctgcggtgg tgaagcgggt ccggtaattg atatcactaa
     6601 cgaagcaacg ctgccgaagc gtgcaaccat cactttacgt cgtagcaaac tggatcgcct
     6661 gatcggccat catattgctg atgagcaggt aacagacatt ctgcgtcgtc tcggctgcga
     6721 agtgaccgaa ggcaaagacg agtggcaggc agttgcgccg agctggcgtt tcgacatgga
     6781 gattgaagaa gatctggtcg aagaagtcgc gcgtgtttac ggctacaaca acatcccgga
     6841 tgagccggta caggcaagcc tgattatggg gattcaccgt gaagctgacc tgtcgctcaa
     6901 gcgcgtaaaa acgctgctca acgacaaagg ctatcaggaa gtgatcacct acagcttcgt
     6961 tgatccgaaa gtgcagcaga tgatccatcc aggcgttgaa gccttactgc tgccaagccc
     7021 gatctctgtt gaaatgtcag caatgcgtct ttctctgtgg accggcctgc tggcaaccgt
     7081 ggtgtacaac cagaaccgtc agcagaatcg tgtacgcatt ttcgaaagcg gtctgcgttt
     7141 cgtgccagat actcaggcac cgttgggtat tcgtcaggat ctgatgttag ccggtgtgat
     7201 ttgcggtaac cgttacgaag agcactggaa cctggcaaaa gagaccgttg atttctatga
     7261 tttgaaaggc gatcttgaat ccgttctcga cctgaccggt aaactgaatg aggttgagtt
     7321 ccgtgcagaa gcgaatccgg cactgcatcc ggggcaatcc gcagcgattt atctgaaagg
     7381 tgaacgtatt ggttttgttg gggttgttca tcctgaactg gaacgtaaac tggatcttaa
     7441 cggtcgcact ctggtgttcg aactggagtg gaacaagctc gcagaccgcg tggtgcctca
     7501 ggcgcgcgag atttctcgct tcccggcgaa ccgtcgtgac atcgcggtgg tggtcgcaga
     7561 aaacgttccc gcagcggata ttttatccga atgtaagaaa gttggcgtaa atcaggtagt
     7621 tggcgtaaac ttatttgacg tgtaccgcgg taagggtgtt gcggaggggt ataagagcct
     7681 cgccataagc ctgatcctgc aagataccag ccgtacactc gaagaagagg agattgccgc
     7741 taccgtcgcc aaatgtgtag aggcattaaa agagcgattc caggcatcat tgagggattg
     7801 aacctatggc gcttacaaaa gctgaaatgt cagaatatct gtttgataag cttgggctta
     7861 gcaagcggga tgccaaagaa ctggttgaac tgtttttcga agagatccgt cgcgctctgg
     7921 aaaacggcga acaggtgaaa ctctctggtt ttggtaactt cgatctgcgt gataagaatc
     7981 aacgcccggg acgtaacccg aaaacgggcg aggatattcc cattacagca cggcgcgtgg
     8041 tgaccttcag acccgggcag aagttaaaaa gccgggtcga aaacgcttcg cccaaagacg
     8101 agtaatctga tctaactaaa aaggccgctc tgcggccttt tttcttttca ctgtcgaaga
     8161 gtcaccgtaa aatcaacgcc atgacacttc agcagaacgg ataccatgct gacacttgcc
     8221 cgccaacaac agcgacaaaa tattcgctgg ttattatgcc tgtcagtttt gatgctgctg
     8281 gcgcttctct taagcctttg cgccggtgaa caatggatct cgccaggtga ctggtttact
     8341 cctcgtggcg aactgttcgt ctggcaaatt cgcctgccac gtacgctggc tgtattgctg
     8401 gttggtgctg cgttggctat atccggcgct gtaatgcagg cgttgtttga aaatcctctg
     8461 gcagaacctg gactacttgg cgtctctaac ggcgcaggcg tggggcttat cgccgcggta
     8521 ttgcttgggc aagggcaact ccccaactgg gcgctggggc tgtgtgcgat tgctggcgcg
     8581 cttatcatca ctttaatact cttacgtttc gcccgtcgtc atctttcgac cagtcggtta
     8641 ttgctggctg gcgttgcatt agggattatc tgtagtgcac taatgacgtg ggctatctac
     8701 ttttccacct ctgttgattt acgtcagctg atgtactgga tgatgggcgg ttttggcggc
     8761 gtagactggc ggcaaagctg gctgatgctg gcattgatcc ccgtgttgtt gtggatctgt
     8821 tgtcagtcca ggccggtgaa tatgttagca cttggcgaga tctcggcgcg gcaactgggt
     8881 ttacccctgt ggttctggcg caatgtgttg gtcgcagcga ccggctggat ggttggcgtc
     8941 agtgtggcgc tggcgggtgc tatcggcttt attggtctgg tgatcccaca tattctccgg
     9001 ctgtgtggtt taaccgatca tcgcgtatta cttcccggct gcgcgctggc aggggcgagc
     9061 gcattgctgc tggccgatat tgtagcgcgc ctggcattag ctgccgcaga gctgcctatt
     9121 ggcgtggtca ccgcaacgtt gggtgcgccg gtgtttatct ggttattgtt aaaagcagga
     9181 cgttagccgc aaaaagacgg tctatgatta aaagctaaga tttttactga ccacacccag
     9241 gagaaacgat gcaagattcc attctgacga ccgtagtgaa agatatcgac ggtgaagtga
     9301 ccacgctgga gaagtacgcc ggtaatgtgc tgttgattgt caatgtcgcc tcaaagtgtg
     9361 gcttaacgcc gcaatatgag cagttggaga atattcagaa agcctgggcc gatcgtggtt
     9421 ttgtggtgct gggattcccg tgcaaccagt ttctggaaca agaaccgggc agcgatgaag
     9481 agattaaaac ttactgtacc accacatggg gggtgacgtt cccgatgttc agtaagattg
     9541 aagttaatgg cgaaggacgc catccgctgt atcaaaaatt gattgccgca gcgccgaccg
     9601 cagtcgcgcc ggaagagagc ggattctatg cccgtatggt cagcaaaggt cgtgcaccgc
     9661 tgtaccctga tgatatttta tggaattttg agaaattttt agttggcagg gacggattgg
     9721 tcatccagcg tttttccccg gatatgacgc cggaagatcc cattgtgatg gaaagcatta
     9781 aactggcgtt ggcaaaataa tgtctattgt gatgcagtta caggatgttg cggaatctac
     9841 ccgcctgggg ccgctttctg gcgaggttcg ggctggggag atcctgcacc tggtggggcc
     9901 gaacggcgcg ggtaagagta ccttgcttgc acgaatggcc ggaatgacca gcggtaaggg
     9961 aagcattcag ttcgcggggc aaccactgga agcatggtct gcaacaaaac tcgcgctgca
    10021 tcgcgcctat ctttcacaac agcagacgcc gccgtttgca atgccggtct ggcactacct
    10081 gacactgcat cagcacgata aaacgcgtac cgaactactg aatgatgtcg caggggcgct
    10141 ggctcttgat gacaaactcg gacgtagcac caatcaactt tccggcggtg aatggcaacg
    10201 cgtacgtctt gctgcggtgg tgcttcaaat cacaccacaa gctaatcccg caggccaatt
    10261 gctgcttctt gatgagccga tgaacagtct tgatgttgcg caacaaaatg cgttagacaa
    10321 aattctgagc gcgctgtgtc agcaaggact ggcgattgtg atgagcagtc acgatctcaa
    10381 ccacacattg cgtcatgcgc atcgggcgtg gttgctaaaa ggtggaaaaa tgctggccag
    10441 tggacgcaga gaagaggtgc tcacgccggc aaatctggca caggcctatg ggatgaattt
    10501 tcgccgtctg gatatcgaag gtcacagaat gctgatttcg accatctgat ttcattagta
    10561 tcttgaaaat cgggtaatta cgacgctaaa ttaatgcaag aataaaaaac agaggaaccg
    10621 tacggaatgc gtttctgcct tattttgatc acagcactgt ttctggccgg gtgtagccac
    10681 cataaagcac cgccgccaaa tgccaggctt tctgattcga tcaccgttat tgccggtttg
    10741 aacgaccagc tacaaagctg gcatggcacg ccgtatcgtt atggtggcat gacgcggcgc
    10801 ggtgtggact gttcgggatt tgtggttgtg acgatgcgcg atcgtttcga tttgcagctg
    10861 ccccgtgaaa ccaaacaaca agcctctatt ggcacgcaaa ttgataaaga cgagttgctg
    10921 ccaggtgacc tggtcttttt caaaacgggt tccggacaaa atggtttgca tgtaggtatt
    10981 tacgatacca acaaccaatt tatccacgcc tctaccagca agggagtgat gcgttcctca
    11041 cttgataatg tctattggca gaaaaatttc tggcaggcga gacgaatcta gtatgtcgaa
    11101 aaatggacgg cgatgataca tcgccgtcca tttactcctg aatacagtag tattttgcag
    11161 acagaaattc cgtaaatgga ttattcgttt ataatcagga taatctaaaa aaaaggaccc
    11221 ctgaaaaagt ggttaacatg gaacaaatga aagttactcc ttctgtaatt gttatgtctt
    11281 atggcctcat cccttttagc cggatactga aaaacatcct tcgagaggga cggttaccat
    11341 gaagattttt ttggagaatc tttatcattc tgattgctat ttcctgccga taagagataa
    11401 ccagcaagac cttgtcggcg ttgagttaat tacccatttc tccagtgaag atggtacggt
    11461 tcgtatcccg acgagtcggg ttatagcgca acttaccgag gagcaacatt ggcaattatt
    11521 ttctgaacag ttggaattac taaaatcatg ccaacacttt tttattcaac ataaactctt
    11581 tgcctggctt aatttaacgc cacaagtggc tacattatta ttagacaggg ataatttcgc
    11641 aggcgaacta ttaaaatatc cgtttattga actgttgatt aatgagaatt acccgcattt
    11701 caatgaagga aaagataatc gcgatctttt atccttatcg caaatgtatc cccttgtgtt
    11761 aggtaatttg ggagcaggta atagcacaat gaaagcggtg tttgatggtc ttttcacccg
    11821 cgtcatgctg gataaaagtt ttattcagca acaaatcacg catcgctcct tcgaaccgtt
    11881 tattcgtgcg atccaggcgc aaatttcccc ttgttgcaat tgcatcatcg cggggggcat
    11941 tgatacgcca gaaatattgg cacagattat accctttgat ttccatgctc tccagggatg
    12001 cctgtggcct gcggttccta taaatcagat aacgacgttg gttcagcgat aaccctcctg
    12061 tttgctggtg tttaggacga gagtaaccgt ctacactatc aaacaggagg atctatgacc
    12121 ctgtctttta ttacccgctg gcgcgatgaa ttgccagaaa cctatacagc actttcccct
    12181 acgcctttaa ataatgcccg gctgatttgg cataataccg aactggctaa cacgctgagt
    12241 attccatcgt cgctgtttaa aaatggcgca ggtgtctggg gcggcgaaaa cctactgcct
    12301 ggtatgtcac cactggcgca ggtttacagt ggtcatcagt ttggcgtctg ggcgggccaa
    12361 ctgggtgatg ggcgcggcat tttactcggc gaacaactgc ttgctgatgg cactacaatg
    12421 gactggcatc tgaaaggtgc tggcctgacg ccttattcgc gaatgggtga tggacgggcg
    12481 gttttacgtt cgacgatacg agaaagtctc gccagtgagg cgatgcatta tctgggcatt
    12541 ccgacgaccc gcgctttaag tatcgtcacc agcgattcgc cagtgtatcg ggaaacggtg
    12601 gagccaggcg cgatgctgat gcgtgtggca ccaagtcatc tgcgctttgg tcatttcgaa
    12661 catttttact atcgccgcga gccggaaaag gttcgtcagt tagctgactt tgccattcgt
    12721 cattactggc cacatcttgc agatgatgag gacaaatacc gtctctggtt taccgatgtt
    12781 gtcgcacgta ccgcctcgtt aattgcccaa tggcagactg tcggctttgc tcatggggtg
    12841 atgaataccg acaacatgtc gctgctgggg ctgacgcttg attacgggcc gtttggtttt
    12901 cttgatgatt acgaacccgg ttttatttgt aatcactcgg atcatcaagg gcgttacagc
    12961 tttgataatc aacctgccgt cgcgttgtgg aatttacagc gtctggcgca gacattgtca
    13021 ccatttgttg ccgtagatgg cctgaatgag gccctggaca gctatcagca ggttttgttg
    13081 acgcattatg gacaacggat gcggcagaaa ctgggcttca tgacggagct aaaagaggat
    13141 aacgcgctac tgaatgaatt attcagtctg atggcgcgag agcgcagcga ttatacccgc
    13201 acattccgca tgctgagtct gaccgagcag cacagcgcgg cgtcaccgct acgtgatgag
    13261 tttattgatc gtgcagcatt tgatgactgg tttgcccgtt atcgggggcg tttgcaacaa
    13321 gacgagatta ccgataatga gcgtcagcaa ctgatgcaaa gcgttaaccc ggctctggtg
    13381 ttgcgcaact ggttggcgca acgggcgatt gaagcggcag aaaagggtga tatgacggaa
    13441 ttgcaccgcc tgcatgaggc gttgcgaaat cctttcagcg acagagatga tgactatgtc
    13501 agtcgtccac ctgactgggg taaacggctg gaagtcagct gctcgagtta aaggctactt
    13561 ggtcaacagc agcttgccag cctgagtttt acggagcaga tattcttgtc cgtcatgatc
    13621 gataatcagt ttgccatccg gacctaacag tgtctggctg gtaattcgcc ggatgggctg
    13681 cggggaagcg gtcttgtgat tggcatccgt ttcaggcgtg agttttctgc tatccgtata
    13741 acgcataaaa attaataata atttatataa caatgattct tattatcaat attatggagg
    13801 gccagagcaa gcagtaattt gttgagaaga caacaagttg cgcagaaatg cccatcctgt
    13861 caggaatggg cacgcattca gaagcgggta tctaccgcag aggcgagttt ttcgaccagg
    13921 cgttcggtat cttcccagcc cagacacggg tcggtaatgg attgaccgta agtgagcggc
    13981 tgaccgccga cgattttttg cgttccttcg cgcaggaaac tttccgccat aattccggca
    14041 atcgccgtag agccattgcg gatttgctga caaatatcct cacaaacttc taactggcga
    14101 cggtgctgct tctggcagtt accgtggctg aaatccacca ccagatgttc aggcaaatca
    14161 aattcgtgca gcgtatcgca ggctgcggcg atatcatcgg catgataatt cggttttttg
    14221 ccgccacgca taataatgtg gccatacggg ttgccgctgg tctgatagat ggtcatctga
    14281 ccgtttttgt ctggcgagag gaacatatgg ctagcgcggg ctgcgcggat agcatccacg
    14341 gcaatccgcg tgttgccatc ggtaccattt ttaaaaccca ccggacagga gagtgccgaa
    14401 gccatttcgc ggtggatctg actttcggta gtacgtgcgc caatcgcgcc ccaactgatt
    14461 aaatcagcaa taaactgacc ggtcaccata tcgaggaact cagtcgcggt agggacgccc
    14521 agctcattta cctgtaaaag taatttgcgc gccagctcca gaccgtgatt tacccgatag
    14581 ctaccgttta aatctggatc ggagatgagt cctttccagc cgacaaccgt tcgtggtttt
    14641 tcaaaatagg tgcgcattac gatttccagc cgtgactggt actggttgcg cagcgactgc
    14701 agacgggtgg cgtactccat cgcagcggtg agatcgtgga tcgagcaggg gccaataatg
    14761 accaacagtc gcttatcttc accattcagt attttttcaa ttctacggcg ggagtcggtg
    14821 acatgggtgg cgacgccagg cgttacggga taccgtagcg cgagttcggc gggcgttacc
    14881 aggctctcaa tacgcgcagt acggagttcg tcagttctgt tcattacaag tctcagaaat
    14941 ttgttgcttc tacggcagga ctaccgggaa gtgatgcgca tcacgataaa ccaatcgcag
    15001 ctgatttcaa gtgcgaggtg tgtcacacct cgccgggtgg ttagcatgat aacaaaaaaa
    15061 caagctaatg cactagttct ctagtacatt cggcggctaa ggcccatgat atcgaggatc
    15121 ttggtggcaa tctcttctac cgaataattg gtactgttaa tccacgggat ctgattttta
    15181 cggtacaacg cttccacttc cgcgacttcc atcctgcact gacgaagcga ggcatagcga
    15241 ctgttctccc gacgttcctc gcgaatcgcc gccagacgtt ccgggtcgat agtcaggccg
    15301 aacaatttat gctgaagtgg tttgagcgac gcgggtagca ccagattatc catatcatcg
    15361 gcaataaagg ggtagtttgc cgcgcggata ccaaattgca ttgccagata cagactggtg
    15421 ggggttttac cacagcgaga aacaccgagc aggatcacct gagcctggtc cagattgcgc
    15481 aacgaaatac cgtcatcgtg ggcaagggtg taatcaatcg ccgcaatgcg cgcatcatat
    15541 ttattgagat tattagggtt aaggccatgg gtacgatgag caatcggcgt tggatccagt
    15601 ttcatctctt gttgtagtgg ggcaaccagc gcctgaacga tatcctggca aaagccttca
    15661 ctttgcaaga tgatagcgcg aatctccggc aacacgatgg agtagaagac cagcgggcgc
    15721 acacctgtct ggtgataaat tgcgtcaatc tgatccttca ctgcccgtgc acggctctca
    15781 ttttcgacaa acggcagcgt aatgctgctg atagtgacgg gaaattgtga cattactgcg
    15841 tgtcctaata cctccgcagt tattgccgta ccatcagaaa tataaaaaac gtggcgatca
    15901 acagcattat ccattttgtt cttcccgtga tgcagacata attctatgaa agcataaatt
    15961 aaaaacgcac agaagcgtag aacgttatgt ctggtttata aaatgaaact taaattttat
    16021 tttttatgaa aacagcattt catttttatg gtttcgttta taccgatggt ttatgtggaa
    16081 attgtcgaag agagcagatt tgcgcaacgc tgggatcagt cttaaaaagt aaaaaaatat
    16141 atttgcttga acgattcacc gtttttttca tctggttaaa tatgcaaaga taaatgcgca
    16201 gaaatgtgtt tctcaaaccg ttcatttatc acaaaaggat tgttcgatgt ccaacaatgg
    16261 ctcgtcaccg ctggtgcttt ggtataacca actcggcatg aatgatgtag acagggttgg
    16321 gggcaaaaat gcctccctgg gtgaaatgat tactaacctt tccggaatgg gtgtttccgt
    16381 tccgaatggt ttcgccacaa ccgccgacgc gtttaaccag tttctggacc aaagcggcgt
    16441 aaaccagcgc atttatgaac tgctggataa aacggatatt gacgatgtta cccagcttgc
    16501 gaaagcgggc gcgcaaatcc gccagtggat tatcgacact cccttccagc ctgagctgga
    16561 aaacgccatc cgcgaagcct atgcacagct ttccgccgat gacgaaaacg cttcgtttgc
    16621 ggtgcgttcc tccgctactg cagaagatat gccggacgct tcttttgccg gtcagcagga
    16681 aactttcctc aacgttcagg gtgttgacgc cgttctcgtg gcagtgaagc atgtattcgc
    16741 ttctctgttt aacgatcgcg ccatctctta tcgtgtgcac cagggttacg accatcgtgg
    16801 cgtagcgctc tccgccggtg ttcagcggat ggtgcgctcc gacctcgcat cttctggcgt
    16861 gatgttctcc attgataccg aatccggctt tgaccaggtg gtgtttatca cttccgcatg
    16921 gggccttggt gaaatggtcg tgcagggtgc ggttaacccg gatgagtttt acgtccataa
    16981 accgacactt gcggcgaatc gcccggctat cgtgcgccgc accatggggt cgaaaaaaat
    17041 ccgcatggtt tacgcgccga cccaggagca cggcaagcag gttaaaatcg aagacgtacc
    17101 gcaggaacag cgtgacatct tctcgctgac caacgaagaa gtgcaggaac tggcaaaaca
    17161 ggccgtacaa attgagaaac actacggtcg cccgatggat attgagtggg cgaaagatgg
    17221 tcacaccggc aaactgttca ttgtgcaggc gcgtccggaa accgtgcgct cacgcggtca
    17281 ggtcatggag cgttatacgc tgcattcaca gggtaagatt atcgccgaag gccgtgctat
    17341 cggtcatcgc atcggcgcgg gtccggtgaa agttatccat gacatcagtg aaatgaaccg
    17401 catcgaacct ggcgacgtgc tggttactga catgaccgac ccggactggg aaccgatcat
    17461 gaagaaagca tctgccatcg tcaccaatcg tggcggtcgt acctgtcacg cggcgatcat
    17521 cgctcgtgaa ctcggcattc cggcggtagt gggctgtggt gatgcaacag aacggatgaa
    17581 agacggcgag aacgtcactg tttcttgtgc cgaaggtgat accggttacg tctatgcgga
    17641 gttgctggaa tttagcgtta aaagctccag cgtagaaacg atgccggacc tgccgttgaa
    17701 ggtgatgatg aacgtcggta acccggaccg tgctttcgac ttcgcctgcc tgccgaacga
    17761 aggcgtgggc cttgcgcgtc tggaatttat catcaaccgt atgattggcg tccacccacg
    17821 cgcactgctt gagtttgacg atcaggaacc gcagttgcaa aacgaaatcc gcgagatgat
    17881 gaaaggtttt gattctccgc gtgaatttta cgttggtcgt ctgactgaag ggatcgcgac
    17941 gctgggtgcc gcgttttatc cgaagcgcgt cattgtccgt ctctctgatt ttaaatcgaa
    18001 cgaatatgcc aatctggtcg gtggtgagcg ttacgagcca gatgaagaga acccgatgct
    18061 cggcttccgt ggcgcgggcc gctatgtttc cgacagcttc cgcgactgct tcgcgctgga
    18121 gtgtgaagca gtgaaacgtg tgcgcaacga catggggctg actaacgttg agatcatgat
    18181 cccgttcgtg cgtaccgttg atcaggcgaa agcggtggtt gaggaactgg cgcgtcaggg
    18241 gctgaaacgt ggtgagaacg ggctgaaaat catcatgatg tgtgaaattc cgtccaacgc
    18301 cttgctggca gagcagttcc tggaatattt cgacggcttc tcaattggct caaacgacat
    18361 gacgcagctg gcgctcggtc tggatcgtga ctccggcgtg gtgtctgaac tgttcgatga
    18421 gcgcaacgat gcggtgaaag cactgctgtc gatggcgatt cgtgccgcga agaaacaggg
    18481 caaatatgtc gggatttgcg gtcagggtcc atccgaccac gaagactttg ctgcatggtt
    18541 gatggaagag gggatcgata gcctgtctct gaacccggac accgtggtgc aaacctggtt
    18601 aagcctggct gaactgaaga aataaaataa atacccggcg gcgttttgtc gccgggttta
    18661 tgtgatcccc gaagatgaaa cttattcaat ctcttcacag acatcctgag ttaatcgccg
    18721 cataatatct ttccttaaca aaaacttttg tattttacct gagacagtgc gcggtagttt
    18781 ttcgattacc acgatatgtt caggatattt atattttgcg acccgtttac ggctaaaaaa
    18841 agccaccacc tcttccagcg ataatgaatg atgcggcgct ttcagcacga cataagcgca
    18901 tgaacgttca cctaaacgtt catcgggcat cgcaaccaca caggcatcgt gaattttagg
    18961 atgctgcaat aaaatatctt ctacttcacg gctgctaata ttttcgccgc cgcggacaat
    19021 aatatctttc ttgcgcccgg ttatttttat atagccagcc tcatccatgc ggcagagatc
    19081 gccgctgtaa taccagcctt cttcatccag cgcacgggcg gttaattcag gttcatcaaa
    19141 ataccccata aacacattgg ggccacgcga ggcttcttca ccttcgcaac ctggcggtaa
    19201 agtcttgcgt gcgtcatcga ccactttaat ctctacacct gcggcagcgt aaccgtcggt
    19261 gtgcataaag cgcggcaaag gatcgtcgag attcaccacc gcatgcggcg aactttctgt
    19321 ggaaccataa acacttaata atttaatgcc gcgctgctgg cattctcgcg ccactttttt
    19381 ggggattgtg gtacctccgc aaagaaagaa gcgcagcgct gaaaggtctg cgggttgttt
    19441 ctctagtaaa ttcaaaagat catagacaaa cggcgttgcg ccgagcatac aggtgcaacg
    19501 ctgctgctca agcagcgcga gacacgcatc aggagtgaaa atatctaaca acacgctgcg
    19561 agcaccaatc aaaaaaggtg ctgttacgcc atgcagaaag cccgttgcgt gaccaagtgg
    19621 cgcaggcatc ataaagacat cctgccaggt cagatttagc cgcgcgcaat aagcccgctc
    19681 actggcgaga atattgttat gcgttagcat cacacccttt ggcagaccct cggttccgga
    19741 ggtaaatagc acagcggcta attcatcgcc gtgggtcgtt atcgccgtgg tcagaggagt
    19801 attgtcggcg agaatctgac ttaatgagag ggaagaggtg gcgggagcca gtttgtccac
    19861 gccgacaatt tgttgtagtt gtggaagctg attttgcagc ggcaggatta aatctaccgg
    19921 acgcgtttgt ttaaacaacg tcggtgcaaa gaacattttt gcctgacact tattgagcac
    19981 ccacaccagt tctgcttccc gccaggaagg taacagcggc acggaaaccg caccggtttt
    20041 caggcaggca agatagataa cggtaaattc acaccagcct ggcagttgaa atgcgatgcg
    20101 atcgcctgat tcaataccct tcgctaacat ccagtttgcc agacagctcg cggcgtgatc
    20161 gagcgcgcta taggtgtacg ttgcaccatg attatcgacc acggcaattt tgtctggcat
    20221 cgcacgagcg gtctgctgcc agtaatcggc cagcgaagca tcgccccata acccttgctg
    20281 acgatacgcc gcacgacgtt gttcgttgaa cgttaatgtc actttcattt tggactctcg
    20341 aaacagaaca tcaggcccga gatgcgggcc tgtgggatgc atgattagcc gtagcgaaat
    20401 tcaataccga aggtgcctgc gggatattgc cactgttcga gaatagtgtt gccgcacagc
    20461 acccgacagg tgccgcactc cagacaaccg gcggaatcga aatgaatgtt tcctgcgtca
    20521 tcctgcttat aaagtccggc agggcaagct ttcattaatt tacggaattc attgatatcg
    20581 ggatttgccg ccaaaatgat atgcgggtgg ccctcatcaa catggaattt atcgacgcct
    20641 aatttgatgt cgacgttaac cgtagcgttc tggctcatag cgcggttgct cccttaatgc
    20701 catctttcag caagttgatc agcccaattt tcttcgcgtg tcccatgatc attttgcgta
    20761 ccggctggtt tggtttgccg tcaatggtga acatatcgtt catgatgtcg gcgaccattc
    20821 gtgggtattg gctaaacagg cgcgggtttt ccatcagcgc cgggatcttg cggaaatgct
    20881 gcatatcgcg cataacacaa ctttgttcca gctcacgttt gtattgcgcc agactgctgg
    20941 cggagaaatc cgcgcgttct ttggcggcga tcaccgttgt ggcggcagcc tgagctgatg
    21001 caatggctaa atccatgccg cgaactgtaa aacccaaatt caggcagaag cctgcggcgt
    21061 caccaacgat catcacgcca tcgttaacca gctgcggcac cattgccaga ccgccctccg
    21121 gcaccatatg cgcggaatat tcaagcagtt tgccgccgct aatcagcggg cgaatagcgg
    21181 ggtgttgttt aaaatcttcc agcatttgcg gcacgctttt ttgcgcatgg gcgatatcac
    21241 ccaatccaca aaccagcccc aacgatacgg aatccttgtt ggtatagagg aatccgccgc
    21301 ccatcaggcc gtcagaaggg gaaccggcaa acagccaggc ggcaccttcc tcgcccgtaa
    21361 cattaaagcg atcgttgatc tgttctggtg tcaggcctat aacctcttta acaccaacag
    21421 cgtaatgatg cggattggaa gcggaaacca ttcccagcga gcggccaagc atcgagttaa
    21481 cgccatcagc cagaatcacc acattcgctt cgagaatatc atccccggcc tggacgccag
    21541 tgaccttgtt tccttcacga accagcgcat cgacgcgtac gcccgggata aactgcgcgc
    21601 ccgcctgctc ggcttgttcc atcaaccacg ggtccagacg attacgcaat acggtataag
    21661 acgcgtgttg cggaacatct ggttgctcgc ggtgaaaatc gagggtaacg gcgctttctt
    21721 cggttaagaa ggagattttc tcgcgtgtga ccttgcgttc taccggcgct gatgctgcaa
    21781 agcctggaat aattgcttca agtgtgtggg cataaagacg cccgccggtc atgtttttac
    21841 atccggcact gtcgccgcgt tctatcacca ggacatccag cccggctcgc gccatgacca
    21901 gtgcggcaac gctaccggca acgcccgcac cgaccacaat ggcatcaaat ttgtcatccg
    21961 acatgcgtta tgctcccttc ccgctgcgtt tacagcggga gatgtggttg aaagggaatt
    22021 agcgattcaa ctggctaatc agggcaggga cgactttgta gatatcgccc accagaccgt
    22081 agtcggcata gttgaagatt ggcgcatttt tatctttatt aatggcgaca atcacttttg
    22141 cgccgttgcc gccaaccata tgctggatct gcccggagat ccccagcgtc aggtagagat
    22201 cggatttcag caacacgccg gagacaccga tataacgttc acgctccatc cagttctcgc
    22261 cttcggcaat tggacgtgaa cagccgactt cagcattcag cactgccgcc agttcgtgga
    22321 ccattttcag gtcatcctgc gccgccagac cacgaccgac gccaaccaca cgttttgctt
    22381 tgctcaggtc cacgctgctt gccgctttcg cacggcgttc gcgacagaga atttcatgac
    22441 gcggggcaac ataaggtacc gtttctgtcg ggcactgatg agagatatca cgggtgcacg
    22501 gttcctgaac accgggtgca agggtaatga tcgccagcgg gctgttgatc ttttcctgag
    22561 cgaacgctaa cccgccatac atccggtgtt cggcgcaaat gtgaccatcg acaatatcca
    22621 ccgccgtggc atcgttcacc agcgccgcat tcagttgcac acttaaccgt gcggccagag
    22681 ctttaccacg tttcgtcgcg gccaacagca acatagcggg gtgtttatct ttcagcaggg
    22741 cagcaatgct ttcggcgtaa ttttcagtac gttgcagcgc gtcgttttgc tcaagaacat
    22801 aaatgcattt tggcccataa ggcataactg cctgcgcctg ctcggtattt tgtacaatgg
    22861 catacacctg ttggccccat tgctgagcgc tgccaaacag ttcagcataa cgttcaggat
    22921 tatcgctaaa gacccagacg ctgtttaatt gactcatcgt ttcttctccg taggcttcag
    22981 ttcagggctt tcttcagatg ttccgccagc tcggcaatgg cctccggcga atcgttatcg
    23041 agaatgatgt gcttacgttc tgtttgcggc ggtacgcgaa tgccggtcag ttcagcaagt
    23101 ggtgcgctct ggctccagcc aatatcactt gcctgccact gatttaccgg ttttttaccc
    23161 gcgccgagaa tggctttcat cgaaggaata cgtggcacgt taatatcgga ggtgacgcag
    23221 agcacggctg gaacagagag ttcaataact tcaacatcat cttcaagcgt gcgttcaatc
    23281 accagtgtat tgccctgacg ctgaatagca ctcactgcat taatcaccgg aagttgcaga
    23341 atttctccga ccagcaagcc aacctgctgg gcataaaggt cgccggaacc ttcaccaaag
    23401 atcagtaaat cgaagccgat cttttcaact gctgtcgcca gcgcctttgc ggtatcgaga
    23461 ggcagtgcat gctcaagttg tgcatcctgc accatataca ggctgtgcgg cccgcgggat
    23521 agcacgtctt tgcgcacttt cgagttctgc aacaaagagc cgccgacggt cagcgcggct
    23581 atctcatcgt catctgttgc aagctggctt gcagcttcaa tggcattgag atcgaactgg
    23641 ctgattttgg cgtcggcatt gtcgaaattc agggtgtatt ctggagtgac aacaatgtcc
    23701 tgttcttcag gcaccagctt aaagcaggtt attattttca tgatttctcc tgtgagtcgc
    23761 atacggaacc atctccgatg gaaagtaaaa atggcctgaa aatagtgtgc gatagcggtg
    23821 cggggttttc gacggagcaa gctgttttcc ttgccaacaa tcttgcaaaa aaaatgcgat
    23881 cgctaaaaca aaagtgcaat ttgcggcaat atagttattc catgaccgta ctatcttgca
    23941 ttcagtgtaa ataatcttgt ttagctctcg ctaaacgcgg ttgtataacc gcaatacacg
    24001 ccgtatttta tccggcatat attgtttttg cttgctcatg gaatagggag gttgtcatgt
    24061 atcaacgctg ttttgataat gccagtgaaa cgctgtttgt cgccggtaaa acgccacggc
    24121 tttcacgttt cgcatttagc gatgatccaa aatgggagtc tggacatcac gttcatgaca
    24181 atgaaaccga gctgatttac gtcaagaaag gggtagcaag gtttaccatc gattcttcgt
    24241 tatatgtcgc gcatgccgat gacattgtgg tgatagaacg tggcaggttg catgcggtgg
    24301 cctctgacgt taacgatccg gcaacgacgt gtacctgtgc gctgtacggc tttcagtttc
    24361 agggggctga ggaaaatcag ctactgcaac cgcattcttg cccggtaatt gccgcaggac
    24421 agggaaaaga agtcattaaa accttattta atgagctaag tgtgattttg ccgcaaagta
    24481 aaaatagcca aacatcttcg ttatgggacg catttgccta tacgttagca attctttact
    24541 acgaaaactt taaaaatgct tatcgttcgg agcagggata tattaaaaaa gatgttctga
    24601 taaaagatat tcttttctat ctgaataata actatcgcga aaaaatcact ttagagcagt
    24661 tatcgaaaaa atttcgtgcc agcgttagtt atatctgcca tgaatttacc aaagagtatc
    24721 gtatttcccc tattaactat gttattcaac ggcgtatgac ggaagcgaaa tggtcactca
    24781 ctaatactga attatcacag gcagagatct cctggcgtgt gggttatgaa aatgtcgatc
    24841 actttgccaa actgtttttg cgccatgtcg gctgttcgcc cagcgattac cgcaggcaat
    24901 ttaaaaactg ttttgcggaa caagaaatcc tatctgaatt tcctcaacca gtaagtcttg
    24961 ccggataaat ctggcggcgc agtttgttaa gaagctgcgc cgcctgcaga ttatttgttc
    25021 tgataatctt tcaggatctg ccgacctgct acgtaaatca taatttcgtc tgtaccgccg
    25081 ccgatacgtt cacaacggac atcacgccag aagcgggaga cgcgcgcctc atcggtatag
    25141 cccagaccgc ccatgatttg aatcgcatca tcaatgactt ccattgcggt acgtgcgcag
    25201 tacagttttg ccagcgccgc gctggtgcgc agtgactgat gctgatcggc ttgccatgcc
    25261 actttcaaca ccatgttgcg catgttgtcg atcttaatcg ccatcagcgc cagtttttcc
    25321 tggatcatct ggttatgacc aatgggctta ccaaaagcga tacgctggtt ggcatagcgg
    25381 gcggcatctt cgaatgcgca ttcggcaaag ccggtgctgc gcgcggcgtt gatcaggcgc
    25441 tccatctcaa agttgtacat cacattgagg aaacccattc cttcttcgcc caccatgtcg
    25501 ctctcttcaa cttccacgtt gtcgagatag acttcgcagg tgctgagcat atgccagccg
    25561 attttatgca gtggattgat tttaatgccg ggcttactgg agtcgaccca ccacagagta
    25621 aaggcctttt tcggatcttt cggttgcgga tcgcgcgcca acaccagcat atatggatac
    25681 tctttcgcac cggtaataaa ggttttctgt ccgttgatgt aaaccttgcc gtttttacgc
    25741 gtgtaagtgg tagtggcact gttgttgtct gagcctgcgc ctggctccgt caatgccagg
    25801 gcataggcgg gatcacccgt ttccagggtg ctctctgccg ttttacgtag ctgctctgca
    25861 gaaccgaaac ggcgcatact gtgaatacat tgaccgttgg taatcaaaaa tgccggagca
    25921 ccgcattttg acacttccat cagcgccagc atttgggtga cgtaatccgc agggatacca
    25981 ccaaattctt ccggcacgcc aagcatggaa ataccgttat ccgccagtgc ccgcataaac
    26041 tcacgcgggt atgtcccgtt ttgatcgcag gtgcggaaat actcttccgg aaagttagtc
    26101 gtaatcagtt cgcgaatact ggccagcagc agttcttgtt cttcagttaa agagaaatcc
    26161 atcattatac tcctgttaat gagccgcttc aggcaggaca aaacccatcg ccgcatcgat
    26221 aaataatctt tcgtccatca gtttgagttc tggcgaaatc actggggtga aatccatttt
    26281 gtcgagaata tctttttgta aatcgacgcc aggagcgatt tcgattaaat gcaggccgtc
    26341 ttcttttagc gtgaatacgg cgcgctcagt gatataacga acatccagcc ctcgctcgag
    26401 agcgattttt ccgctgaaag ttatttccgg tagttcccga ataaatttct tcacccgtcc
    26461 ttcctggacg atatttaatt tgccgtcggt aatttctgtt tttaaactgc ccgcagttaa
    26521 tgtgccgcag aaaacgattt tcttcgaagt ggcactgata tcaataaatc caccggtgcc
    26581 catgatttta ccattgaatt tatgcacgcc gacgttaccg tgctggtcga cttcagcaaa
    26641 actcaaataa caaacatcca gaccaccacc gtgataaaaa tcaaactggg acgtcatatc
    26701 cagaatggcg cgggtattca cgttcgcgcc aaaggcgatc ccctgtgaag taataccgcc
    26761 aatcggacct gtttctaccg tcagaataaa gtcatcagca caaccttctt cccgggcgac
    26821 caggccaatg ccgtcagcaa taccgacgcc gacattcccc actgcgcctt tgcgcatttc
    26881 gaataatgca cgccgtgcaa ctaatttacg ttggtttagg ggcaggctaa gtttggtgct
    26941 gtcatcaagg gtgaagtcac cagaaataaa gcggttaacc ggcgcaccgc catacagttg
    27001 ggtttgatcc ggatcgacca ccacaatatc caccagataa cccggaatac ggacagattt
    27061 aggatgcagc gtggctttct taaccatttt ctgcacctgc atcatcacaa taccgccgtt
    27121 attgtgcacc gcctgggcaa taaccaatgc gtcgagatac atcacctcat cttcaaaagt
    27181 ggcgtagcct tcgctgtcgc aggtggtagc gcgaatgaag gcgatatctg gcgcaatcgc
    27241 tttgtaatag agatattctt tgttatcaaa ctcgaccagt ttaatcaggt cttctttagt
    27301 gacttcattc agtttgccgc cttgctggcg tggatcgaca aatgttccga tgccaatatc
    27361 actaataata ccaggctggt gggctgcggc ggcgcgtaag gtttgtgtaa gtacaccttg
    27421 tggatagtta taagcaataa ttttattttg ttctgcgaga tcagaaatac gcggtgattg
    27481 tccccagtga ccgcataatg cccatttcac caggccttct tgcgccagcg gactaatacc
    27541 acggtcggcg cgatcgccaa gccctgttgg actaataatc gataaattac gtggtgtttg
    27601 agtctgttta tatttatcag caagagcagt aattaacgtg gtggcttcca gaataccgcc
    27661 gccagcgcct aacacacaaa gtgttgcttc gtcgggaata taattcaccg cttcctgtgc
    27721 cgataggacc ggcactcgtc cattaatacg aggtggtttt acaggtttca ttgttaattc
    27781 ctgattcagg tgtgattttc cctacgccag atggagaatt agcgcacaga gactcacgaa
    27841 atatttttat taaatacggt taaaaatact ttttttagtt cggcgggaga gggtattccc
    27901 gccgaaaata ttattgctta tgcctgatgt aaaatagtta ataccgtacg caaatcattt
    27961 accgagattt gccctggcgc agaggctttt tttaccgcac caaaagttgc cgccgaccca
    28021 aatacttcac cagccagacg agaaattacg ccagtttttg ccatcgacat cgtgatgatt
    28081 ggacgatcgg catactgctc ctgcatctcc agggtcgcgg caagcaacgt cagcacatcg
    28141 ctggtacttt gcggcatcag cgcaatctta ggaatatcgg cgtcgaagga ctgcattttg
    28201 cgcagacggg caatgatttc ttcggcttcc ggcgttttat ggaagtcatg gttggacatg
    28261 acaactttca catcatgcgc gtgggcgtag gcgacggttt ctttaacctg atcatcgccg
    28321 gtaaataact ccagatcgat catatcaacc aggccgctgt cgatggctgc acgattgagt
    28381 gcaatataag cctcggtgga aatcgcctgc tcgccgcctt ctttggcact gcggaaggta
    28441 aacagcagcg gtttttctgg catggtttca cggagaattt ttgctgccgc catgacagac
    28501 tccacattgg agaggtcggc atagtggtcc acacgccatt ccagaatatc aaagtccgct
    28561 tcacgatagg cgagagcttc ggatttcacg ctggcgatat ctttcgccat cagcgagacg
    28621 atgattttag gtgcgcccgt accaatgacg agatctttta cagttacggt tttcattttt
    28681 taccctttct gcacgcggtc agcctgtcag gcaccgaacc ccatgacctg tttaacatat
    28741 tccagaggga aatctttgcc agtccataac gtgaactgtt cagccccttg ccacaacaac
    28801 atgccgtatc catcaatcgt tttgcaaccc gcttgttgcg cctgctgcaa taacttcgtc
    28861 atatgagggt tatacacgca ttcagtgacc agaagtcccg ggtgtaacag actgatatca
    28921 ttaaccaatg attcattctc aaggggttcc atacccactt tggtgccatt ggttaaaatg
    28981 tcggcggaag ccagggcttc tgcaaaggct tgctgatcgg cgagatcggt gactgtcacg
    29041 acgcaatcgg tgttttcgtt aacccgctgc gcgaaggcga gagctttatc gaagaactca
    29101 tcccgacggt taaagagttt aatttctttt aaaccttcaa ttgccccctg cgcgccaatt
    29161 gccgttgagg caccaccggc ccctaatagc accatcgttt tgcctttgat atcaaaaccg
    29221 ctctctttaa tggcgcgaat atgacccgtg ccgtcggtgt tatagccacg cagatagcca
    29281 tcatcattta cgatggtgtt gatggcaccc accagtttgg ccgctggcgt taattcatca
    29341 acatattcac acgccagttg tttgttcggc attgatacac cagttccgcg cattttgagg
    29401 gcttttaatc cttcaattgc tccgggaaaa ctatcgttat ccacttcaaa ggccatatag
    29461 gtaaatggca atcccgcttt ttctaaggct ttattctgca tttcgggcga taaactgtgg
    29521 cggatgggat aggccatcaa cccaatcaat tcgtattttg cggtaacatc cataattaac
    29581 tcctttaacc tctatgctta attgtgttta accgggtgct aaatttatgc tcgccaaacc
    29641 gcacatcatt ttcaggaata atgaaaacgc ggtaatagcg gataaaaaca ataattgcgg
    29701 taatcagggc cagcagcgcg aaagtaaaat cgagaacaat gatatattgc aggccgatgt
    29761 tcgacagata accggtaatc agcggaataa caaagttagc cagtccaccc atcatcatat
    29821 atatactggt gactttggct ttgctttttg ggaaaaactc tgacatgacc gaaacgccga
    29881 gctgtaaaat gccgccagct gctgagaaac cgataacaaa ggctccggca ttacacacca
    29941 atggagatgg gtacaggtag ataatggcag ctgttattgt tgccagtgca gagttaaata
    30001 cattagccca gatgggccgg accatttttt tcagcagtgc ggcaaaaata aagacacaga
    30061 ccagcgaacc catactgtaa taagagatgg tttttaatgc ctcagcttct gacataccag
    30121 caaaagccat cgcatatttg ggcatccaca ccacaatcac ataaaaggtc gagaatgcgg
    30181 ctacaccgaa cagtactgat gaaacacctt ccagccagac taacggtttg ctgttcattt
    30241 gcggtaattc attagctacg ctggcgtcca ccaactggct ggggaatttg cttttcaaca
    30301 gcatcagcgt gatcagtaca aacagaatac ccggaataat cagcccatag ccgtaccaga
    30361 tgttattgag caacatatag ctcaccagca ttggatagaa catttgcccg aatgacacca
    30421 tcgctttaac cagtatgacc gccgaaccag aggctttcgg aaagcattcc atgagcgcgg
    30481 ggtagccacc cgtatccagc gctgagttag cgatacctac gcacactgcc agacagtagg
    30541 cgagagttaa attcgggcaa gcaggaatac caaagaagaa tagcagatac attattactg
    30601 ccattaatat caccgcccga cgaccaaact tatcggagat cactccgaag aataaaatac
    30661 tgatcaatcg ccccaatccg ataccggaaa ttaaataggc aatgcccgcg ttgtcagtgg
    30721 aaaacttttc tgccaaagat gtcatgtttt gggcaagcgt aataacacta atgccgtgca
    30781 ggaaatagct gaagtaaata caaagaacag ccaggataaa tggcgtgctg aaagccttat
    30841 tttgagacat gttcacagct ccttgctgaa agataatttc gttaccgtac gtattgttct
    30901 ccgacggttt acataattac tatactgaag atgattttcc ctgggtacat ggcataaagt
    30961 ttatgtttcc aggaatattg catgtcatag tttgtttttg atcgctattt tccttagtta
    31021 gcgcagaaag agttatttat ccgtaagatc ttgcataacc tgaaaagaat attgcattac
    31081 ccacccggag cgatattttc ctttagcgtg tgatgccgcg tttctttgcg actgcgtaag
    31141 ccaataaaca gtgccagtat aaagccgata gcagcgatgg cggtatcgaa ccacataata
    31201 tcggcaatac ttctttgcga aagatgagcc gtaatcaacg gaatggtaaa tgttgcaatg
    31261 ctgcccgcac tgtaatagat ccccgtagct ttacctttag cgtagggaaa acgttccgcc
    31321 attaacgtca ggccaatttg tacaacaccg cctgcggagg taaaaccgat gacgaaagca
    31381 aatattatca ccacataaaa tgtgggatgc aggcagacgg tgagcagggc gataaatgag
    31441 ataaaggtgt acagcatcag taatgttgtt gggcgaacgg tattacgaat gagtggagca
    31501 gtaataaata cacacagcag cgaacccacg gtgtagatac tgagtaattt gatcgacatg
    31561 gtgtatgaca tgccagcgac aaattgtccg tattgtgcca gccactggct aaccagataa
    31621 aacgttgcca ttgagatata gccatatagg gaataactgg ctaaatcgat aattgaacag
    31681 cgatgttccg tagagctggt ggttttcttt atgacaggta agtgacgacc cggatggggt
    31741 gggaacgtac aacggtataa aaacagagcg ttaataaaca taatgcctgc ggcaatcata
    31801 aaggaccaac cgaaccacag ttcagcccac actaacaggc tgataattag cggtaataaa
    31861 aattgtccgc tggaaacaaa tgctttaatt aaaatattgg ctgtacccgg tgagcgtgga
    31921 aaagcttcca tcaaactggg ataggtgcct gcatcgagaa aactgtttgc cattcccgcc
    31981 agaaagccaa aaacataagc gataatgatg ttattggtgt gcaggatgcc aaaaaagaag
    32041 gccatatagc agcacatccc gagcatgata aaagggcggc gaccaaagcg atcggataat
    32101 aatcctgcaa aaagcaagac acttaatcga ccaatgccca gtgatgagat aactatcgag
    32161 acgcccgcgg cattagtctg ccaaagcgtc tccagcgagg ccatattcag gctcatcaaa
    32221 atgacgccca taccatgcac caggtaatta aaatacaacc caagtgcggt agggtaatag
    32281 ggatttttca taggttctac ttagcaaagg tgctttaaaa agtgtagcga tgttgtgtca
    32341 gtatccgttc attattgttg taacaacgac aattcctttc tgtggagaaa ttaacaaagc
    32401 cgctccagat cgtgtgcata taattcagcg gctaccgatt gatagatctt ccagtcaata
    32461 aaattgccat cagggtagac ttgttgaaac gcggttaagt cggggaaaaa acgcatggtg
    32521 ttgttgccga tgcggttatt tattttctct atgattgcat gaagatgttt ttttcgttgc
    32581 tgacgcatag ccaacagttg ctcgactaca taatcaggaa tggcgcattt gccattttcc
    32641 cactgacgcc agctttcact gttaccggtc tgggcaatcc aggtcgcgca ttcatcaata
    32701 gtcatggcaa aaatatggcg aagtgcctgg agttcataag cgttcatcgt gtaatggctg
    32761 catgaaataa acaataaaat ataaataaca ttatcagcct gctgacggct tgaagagagt
    32821 cacagtatct tgtgcaacat tattggaaag agtgaggggc gaggtagcga agcagaaaaa
    32881 tgttaaaaaa aagcccatcg tgggagatgg gcaaagacta cacacagcaa ttcgttgttt
    32941 cactcagggg atttccatgc ttataaatca atatgttgat ttataaccgt gagctaatag
    33001 taggcatacg gactttttgc gtcgatcaga ttcgtctcat tagtttaaaa actgtaaaga
    33061 atttgcgaca ggtactacca gctgaatagc ggtaagcagg aaaatatggg gaagagcaag
    33121 caaatatcaa ttagcagggg ttaacaatca ggcggcagag ccgcctgatg agaaattact
    33181 tattcgattt ctcgatttcg ccaagttctt cgagaatttc ttccggttgg tccgtcggcg
    33241 gtgggacttc ttccacccac gcggcaaaca gacgccagga aacggctaac agaaccggac
    33301 caataaacag accgatcatc ccgaaagcaa tcaaaccacc aataacgcca gagaggatca
    33361 ggatcagcgg taaatcggca cccatgcgaa ttaacattgg gcggatgacg ttatcgagcg
    33421 tgccaaccac accgctccaa actaacaata ccgttcccca ggtggtatcg ccagtccagt
    33481 agagccagat aatcgccgga atcagtaccg gcaacggtcc aagctggaca aggcaggaga
    33541 ggatcattaa caccgttagc aaagttgcat aaggtacgcc ggatacggcg aggccgatac
    33601 cgccaagcac tgcctgtact aacgccgtca ccaccacacc cagcgccacc gcgcggatag
    33661 cctgtgccgc cagcagcacg gcggcatctc cgcgaacgcc tgccagacgg gttgcaaaat
    33721 ggcgaatgcc ttgtgccacc tgttcaccgc gccagtacag cagggcgctg aagagaagca
    33781 tcagcgcaca atgcaccata aagcgcccga tatgcgccgc ctgcccaacg aaccaggtgg
    33841 tggtggtgcc aatataagga cggactttcg ccatgatcgc cgtccccccc atatccagca
    33901 aattgtgcca gcctgcatat agcttcgcgc caatcaccgg aatggtatta agccacgcca
    33961 gatcgggtaa cgtcatgtca ccactggaaa tggctttaat tagcgggccg ctgccgtcga
    34021 cgatactgtt aaccagcaaa gcaataggga tgataaacac catcactaat aacagcgtca
    34081 tcaccagaac ggcgagagag cggcgaccaa acatgatctt ttgcaaacgt aacaataccg
    34141 gccaggtggc gataaccact gtaccggccc atgcaaagcc gagaataaag ggttgtacaa
    34201 tccacagaca tgccacaatc atgatggcta aaaacagcac cgaaagcaga atttgtgcga
    34261 catccctggg ctgacgaaca tttaccataa ctacttttca ccttttttgt gcgtcaaatc
    34321 gtcgacgcga cgtgaacacg cgaaactcac ctgcataatg atgagcaatt tcagcggttt
    34381 ttaacaggtc gattctgccc ttaattctga tgggcgtgtt agaaaaaaat gtggtacaac
    34441 aactcaggca acacgcaaac gattaatctc tcatcacaga ccgcaggaaa gggtcaatat
    34501 aatgattcca cagatttccc aggcacccgg cgtcgttcaa ctggtgctta attttttgca
    34561 agagctggag caacagggtt ttaccggcga tacggcgaca agttatgccg atcgtctgac
    34621 aatgtcgact gacaacagta tttaccaact tctccccgat gcggtggtat ttccgcgttc
    34681 aaccgcagat gtagcgctga tcgcccgtct tgccgcgcag gaacgctatt catcgttgat
    34741 ctttaccccc cgcggcggcg gcaccggcac taacggtcag gcgctcaacc aggggattat
    34801 tgttgatatg tcccgccata tgaaccgcat catcgaaatt aaccctgaag agggctgggt
    34861 gcgcgttgag gccggggtga ttaaagacca actcaatcag tacctgaaac cctttggcta
    34921 cttttttgcg ccagaacttt cgaccagcaa ccgggcaacg ctcggcggga tgatcaatac
    34981 cgatgcatcc ggtcagggat cgctggtcta tggcaaaacg tcagatcacg tacttggcgt
    35041 acgcgcggtg ttgttggggg gcgatattct cgatacgcaa cctttacccg tcgaactggc
    35101 ggaaacgctg ggtaaatcca ataccacaat cgggcgaatt tataacacgg tttatcaacg
    35161 ttgccgtcag caacgccagt taatcatcga caacttcccc aagcttaacc gctttcttac
    35221 cggttacgat ctgcgtcatg tctttaacga tgagatgacc gagttcgacc tgacgcgcat
    35281 tctgacgggt tcagaaggga cgctggcctt tattaccgaa gcgcgactgg atattacgcg
    35341 cttgcctaaa gtacgccgtc tggtgaacgt caaatatgac tcttttgact ccgcgctgcg
    35401 taacgcgccg tttatggttg aggcgcgcgc gctttcggta gagacggtgg actcaaaagt
    35461 gctcaacctt gcacgggaag atattgtctg gcattccgtc agcgagttga ttaccgatgt
    35521 gcctgataaa gagatgcttg ggctgaacat tgtggaattt gccggtgatg atgaggcact
    35581 gattgacgag cgagttaatg cactctgtgt gcggcttgat gagctgattg ccagccaaca
    35641 ggcaggagtg atcggctggc aggtgtgccg cgagctggcg ggtgttgaac gtatctatgc
    35701 gatgcgcaaa aaagccgttg gtctgcttgg caatgccaaa ggtgctgcta agccaattcc
    35761 gtttgctgag gatacctgcg taccgccgga acacctggcg gattatattg ctgaatttcg
    35821 cgcgctgctc gacagccacg gcttaagcta cggtatgttc ggtcacgtcg acgcaggtgt
    35881 cttgcacgtc cgtccggcgc tggatatgtg cgatccgcaa caagagattt tgatgaagca
    35941 aatctctgat gatgtagtgg cgcttaccgc gaaatacggt ggtttgttgt ggggcgaaca
    36001 cggcaaaggt tttcgcgccg aatacagccc ggcgtttttc ggtgaggaac tttttgcaga
    36061 actgcgtaaa gtgaaagcgg catttgaccc gcataaccga ctcaaccccg ggaagatttg
    36121 cccgccagaa ggtttcgatg cgccgatgat gaaagtggac gcggtgaagc gcggtacatt
    36181 cgatcgacag atccccattg cggtacgcca gcagtggcgt ggtgcaatgg agtgtaacgg
    36241 caacggttta tgcttcaact ttgatgctcg tagtccgatg tgtccgtcga tgaagatcac
    36301 ccagaaccgg attcattcac cgaaagggcg cgctacgctg gtacgtgaat ggctgcgttt
    36361 gttggcggat cgcggcgttg acccactcaa actggaacaa gaacttcctg aatccggagt
    36421 cagtttgcgg acgttaattg cccgcacgcg caatagttgg catgcgaata aaggcgaata
    36481 tgacttctca cacgaagtca aagaggcgat gtcgggctgt ctggcctgta aagcgtgttc
    36541 gactcagtgc cccatcaaaa ttgatgtgcc ggagtttcgc tctcgtttcc tgcaactcta
    36601 tcacacccgt tatttacgcc cgctgcgcga ccacctcgtc gctacggttg agagttacgc
    36661 accgctgatg gcacgcgcgc cgaaaacctt taatttcttc attaaccagc cgctggtgcg
    36721 caaactctcg gaaaaacata tcggcatggt tgatttgccg ctgctgtcgg tcccctcgct
    36781 acaacaacaa atggtggggc atcgctcggc aaacatgacg ctggaacagc ttgaagctct
    36841 caatgcagag cagaaagcgc gcacggtgct tgtggtgcag gaccccttta ccagctatta
    36901 cgatgctcaa gtggtggcgg attttgtccg tctggtcgaa aaattaggtt tccagcccgt
    36961 gttactgcca ttttcgccaa atggcaaagc ccagcatatc aaaggttttc ttaatcgttt
    37021 tgcgaagacg gcgaaaaaga cggcggattt cctcaaccgt atggcgaagc tgggtatgcc
    37081 aatggtaggc gtcgacccgg cgctggtact ttgttatcgc gatgaatata aactgactct
    37141 gggcgaggag cgtggcgagt ttaacgtctt actggcgaat gaatggctgg caagcgcact
    37201 tgagtcacag ccagtggcta cagtcagcgg tgaatcatgg tatttctttg gtcactgtac
    37261 cgaagttacc gccttgccgg gcgcgccagc acaatgggcg gcaatatttg cccgttttgg
    37321 cgcgaaactg gaaaatgtca gcgtggggtg ctgcggcatg gcagggactt acggacatga
    37381 agcgaaaaat cataaaaatt cgctcgggat ctatgagtta tcctggcatc aggcgatgca
    37441 gcgactgccg cgtaatcgct gtctggcgac cggatattcc tgccgtagtc aggtaaaacg
    37501 ggttgaaggc acgggggtac gccatcctgt gcaggcttta ctggagatta ttaaatgata
    37561 tggaaacgaa aaatcaccct ggaagcactg aatgctatgg gggaaggaaa catggtgggg
    37621 ttgctggata ttcgctttga acatattggt gatgacaccc ttgaagcgac aatgccagta
    37681 gactcgcgga caaagcagcc tttcgggttg ctgcatggag gtgcatccgt ggtactggcc
    37741 gaaagtatcg gttccgttgc cggttattta tgtaccgagg gtgagcaaaa agtggttggt
    37801 ctggaaatca atgctaacca cgtccgctca gtacgagaag ggcgggtgcg cggcgtatgt
    37861 aaaccgttgc atctcggttc gcgtcaccag gtctggcaga ttgaaatctt cgatgagaaa
    37921 gggcgtttgt gctgttcgtc acgattgacg accgctattt tgtgacgttg tcaccagaaa
    37981 agtgtgacgc atattgcttt tggttattat ctgcacagta aacggtggta tactgtgcag
    38041 gtcttgtcta aaagcgagga tgctatgtct actcaacttg atcccaccca actggccatt
    38101 gaatttttac gccgtgacca aagcaatctt tcacctgccc aatatctcaa gcgtctgaaa
    38161 caattagaac ttgaatttgc tgacctgctt actctctctt ctgctgaatt aaaagaagaa
    38221 atctatttcg cctggcgtct gggcgtgcat tgatcctgat ttaatgtcgc gagttcgcca
    38281 aatcggcctg gattaatctt cgtccaggtt cgagggcctt cttaatactg cctatctacc
    38341 cgcctgataa cgttcaaaaa taatacaaat cgcagtttgt gttaaaacag tgggttagct
    38401 ttatgagatt atccttatcg ccccttcaag agctaagcca ctgtgagtgc cggagataag
    38461 cgccggatgg ggtagaaacc cttaagcctg tgtcgcacag acttaagggt tttcttattt
    38521 ctgaacgctg cactttttta cctatccctt aaatagtcat tttcaatgca actttttctt
    38581 tttcatcaca gccttaatgc tccttagata ataatcatta tctaacaatg agatacctaa
    38641 ttcttagcgt gcctgttaac ccacaaatca gggtctatgc ttattaaaag caggtaaaaa
    38701 gcatgtttta cgctaaagcc cctgcgtttg ctgggttgaa ctgataatca ttatcactaa
    38761 catgctgtta tacgctgaaa gcgatgaagt gaggtaaatc gatggacatg cattcaggaa
    38821 cctttaatcc acaggatttc gcctggcaag gcttaacgct gacacccgca gcggcgatac
    38881 acatccgcga actggtggca aagcagccgg gtatgatcgg cgtgcgctta ggcgtgaagc
    38941 aaacgggctg cgcgggcttt ggctatgtgc tcgacagtgt tagcgagccg gacaaagacg
    39001 atctgctgtt tgaacacgac ggcgcgaagc tgtttgtccc gctgcaagcg atgcctttta
    39061 ttgatggcac ggaagtcgat ttcgttcgtg aaggacttaa tcagatattc aaatttcaca
    39121 accctaaagc ccagaatgaa tgtggctgtg gcgaaagctt tggggtatag gcggtactat
    39181 gtctcgtaat actgaagcaa ctgacgatgt caaaacctgg accggcggcc cgctgaatta
    39241 taaagaagga ttcttcaccc agttagccac cgatgagctg gcaaagggga taaacgaaga
    39301 ggtggtgcgc gcaatttcgg cgaagcgtaa tgagccggag tggatgctgg agtttcgtct
    39361 caacgcctat cacgcatggc tggagatgga agaaccgcac tggttgaaag cgcactacga
    39421 caagctgaat tatcaggatt acagctacta ctcggcacca tcgtgcggta attgtgacga
    39481 caactgcgcg tctgaacccg gcgcggtgca gcaaactggc gcgaacgcct ttttaagtaa
    39541 agaggtggag gcggcgtttg agcagttggg cgttcccgtg cgggaaggca aagaggtggc
    39601 ggtggatgcc attttcgact ctgtttcggt tgccactact tatcgcgaaa aactggcgga
    39661 gcagggaatt attttttgtt cctttggcga ggcgatccac gatcacccgg aactggtgcg
    39721 taaatatctc ggcaccgtgg tgccggggaa tgacaacttc tttgccgcac ttaatgcggc
    39781 ggtagcctct gacggtacgt ttatttatgt gcctaaaggc gtgcgttgcc cgatggaact
    39841 ttccacctat tttcgcatta acgcggaaaa aaccgggcag tttgagcgca ccattctggt
    39901 ggccgacgaa gacagctacg ttagctacat tgaaggctgt tccgctccgg tgcgtgacag
    39961 ctatcagtta cacgcggcgg tggtggaagt catcatccat aaaaacgccg aggtgaaata
    40021 ttctacggta caaaactggt tccctggcga taacaacacc ggcggtattc tcaacttcgt
    40081 caccaagcgt gctttgtgcg aaggcgaaaa cagcaaaatg tcatggacgc aatcagaaac
    40141 cgggtcagcg attacgtgga aatatcccag ctgcattttg cgcggcgata actccattgg
    40201 tgagttttac tcagtggcgc tgaccagcgg tcatcaacaa gcggataccg gcaccaagat
    40261 gatccacatc ggtaaaaaca ccaaatcgac cgttatctcg aaagggatct ctgccggaca
    40321 tagtcagaac agttatcgcg gcttagtgaa aatcatgccg acggcaacca atgcgcgcaa
    40381 tttcactcag tgcgactcaa tgctgattgg cgctaattgt ggggcgcata ccttcccgta
    40441 tgtcgaatgt cgcaataaca gcgctcagct ggagcacgag gcaacgacat cacgtattgg
    40501 tgaagatcaa ctgttttact gcctgcaacg cgggatcagc gaagaagatg ccatctcgat
    40561 gattgttaac ggtttttgca aagacgtgtt ctcggaactg ccgctggaat ttgccgttga
    40621 agcacaaaaa ctcctcgcca tcagccttga gcatagcgtc ggataaggaa taaacatgtt
    40681 aagtattaaa gatttacacg tcagcgtgga agataaagct atcctgcgtg gattaagcct
    40741 cgatgttcgt cccggcgaag ttcacgccat tatggggcca aacggttcgg gcaaaagtac
    40801 cttatcggca acgcttgccg ggcgagaaga ttatgaagtg acgagcggca cggttgagtt
    40861 taaaggcaaa gatttgcttg cgctgtcgcc ggaagatcgt gcaggtgaag gcatctttat
    40921 ggccttccag tatccggtgg aaattcccgg cgtcagtaac cagtttttcc tgcaaacggc
    40981 acttaatgcg gtgcgcagct atcgcggcca ggaaacgctc gaccgctttg attttcagga
    41041 tttgatggaa gagaaaatcg ctctcctgaa gatgccggaa gatttattaa cccgttcggt
    41101 aaacgttggt ttttccggcg gcgagaaaaa gcgcaacgat attttgcaaa tggcggtgct
    41161 ggaaccggag ttatgcattc ttgatgagtc agactccggg ctggatattg acgcattaaa
    41221 agtggttgcc gatggcgtga actcgctgcg tgacggcaag cgttcattca tcattgttac
    41281 gcactatcaa cgcattctcg actacatcaa gcctgattac gtccatgtgc tgtatcaggg
    41341 acgaattgtg aaatccggcg atttcacgtt ggtcaaacaa ctggaggagc agggttatgg
    41401 ctggcttacc gaacagcagt aacgcactgc aacagtggca tcatttgttt gaagctgaag
    41461 gggcgaaacg ctccccgcaa gcacagcagc atttacaaca attgctgcgt accggactgc
    41521 cgacacgtaa acatgaaaac tggaaatata cgccgctgga cgggctgacc aatagccagt
    41581 ttgtctgcat tgcgggggag atatccccac agcagcgtga tgccttagcg ttaacgttag
    41641 acgccgtgcg gctggtgttt gtcgatggac gttacgtgcc cgcactgagc gatgcaactg
    41701 aaggcagcgg atatgaagtg agcattaacg acgaccgtca ggggttaccc gacgctattc
    41761 aggcggaagt gtttctgcat ttgacggaaa gcctggcaca aagcgtgacg catatcgccg
    41821 tgaagcgcgg tcaacggccg acaaagccat tgctgttaat gcatatcacc cagggcgtgg
    41881 caggtgaaga ggtgaatact gcccattacc ggcatcatct ggatctggcg gaaggtgccg
    41941 aagcaacggt gatcgaacat tttgtcagcc ttaatgatgc tcgtcacttc accggcgcac
    42001 ggttcactat caacgtcgca gcgaacgccc atttgcagca tatcaagctg gcgtttgaaa
    42061 acccgctcag tcaccacttt gctcataacg atttgttgct ggctgatgat gccaccgcat
    42121 ttagccacag tttcctgctg ggtggcgcag tgttacgaca caacaccagt acgcaactca
    42181 atggcgaaaa cagcacggtg cggatcaata gcctggcgat gccggtgaaa aacgaggtgt
    42241 gtgatactcg tacctggctg gaacacaata aaggtttttg taacagccga cagttgcaca
    42301 aaactatcgt cagcgacaaa ggccgcgcgg tatttaacgg tttgatcaac gtcgcgcagc
    42361 acgccatcaa aacggatggt cagatgacca acaataatct gctgatgggc aaactggcgg
    42421 aagtggatac taaaccgcag ctggaaatct atgcagatga tgtgaaatgc agccacggcg
    42481 cgacggtggg gcgtattgat gacgaacaga tgttttatct gcgctcgcgc gggatcaatc
    42541 agcaagatgc ccagcagatg atcatctacg cctttgctgc cgaactgacg gaagcactgt
    42601 gtgatgaggg gcttaaacag caggtgatgg cccgaatcgg tcaacgactg ccaggaggtg
    42661 caagatgact ttttccgtcg acaaagtgcg ggccgacttt ccggtgcttt ctcgtgaggt
    42721 aaacggtttg ccgctggctt atctcgacag tgccgccagt gcgcagaaac caagccaggt
    42781 gattgacgcc gaggctgagt tttatcgtca cggctacgcg gcggtgcatc gcggtattca
    42841 taccttaagc gcccaggcga ccgagaaaat ggagaacgtg cgcaagcggg catcgctgtt
    42901 tattaatgcc cgttcggcgg aagagctggt gttcgtccgc ggcacgacgg aagggatcaa
    42961 tctggtcgcc aatagctggg gcaacagcaa tgtgcgagcg ggcgataaca tcatcatcag
    43021 tcagatggag caccacgcta acattgtccc ctggcagatg ctttgcgcac gcgttggcgc
    43081 agagctgcgt gtgatcccgc tcaaccccga cggtactctg caactggaga cgctgcctac
    43141 gctgtttgat gagaaaactc gcctgctggc aattactcat gtctccaacg tgcttgggac
    43201 agaaaatccg ctggcggaga tgatcacact tgcgcatcaa catggcgcaa aagtgctggt
    43261 ggatggcgct caggcggtga tgcatcatcc ggtggatgtt caggcgctgg attgcgattt
    43321 ctacgtgttt tccgggcata aactgtatgg tcccaccggc attggcgtgc tgtatgtcaa
    43381 agaagccttg ttgcaggaga tgccgccgtg ggaagggggc ggttctatga ttgccaccgt
    43441 tagcctgagt gaaggcacta cctggaccaa agcgccgtgg cggtttgaag ccggtacgcc
    43501 caataccgga ggtattattg gccttggcgc ggcgctggag tatgtttcgg cgctggggct
    43561 taataacata gccgagtatg aacagaatct gatgcactac gcgctagcac agctggaatc
    43621 tgtaccggat ctcactctct atggcccaca gaacaggctt ggcgttattg cttttaatct
    43681 cggtaaacac cacgcctatg atgttggcag ttttctcgat aattacggca ttgctgtgcg
    43741 taccggacat cactgcgcta tgccattaat ggcctattac aacgtccccg cgatgtgtcg
    43801 ggcgtcgctg gcaatgtaca acacccatga agaagtggat cgtctggtaa ctggattgca
    43861 acgtattcat cgtctactgg ggtaaaaggg aggctctatg gctgtattgc cggataaaga
    43921 aaaattgctg cgtaactttt tacgctgcgc caactgggaa gagaaatatc tctacattat
    43981 tgaactggga cagcgtctgc cagaattacg tgacgaagac aaaagcccgc aaaatagcat
    44041 ccagggctgc cagagtcagg tgtggattgt aatgcgccag aatgcgcagg gaattattga
    44101 attgcagggc gacagcgatg cggccattgt aaaagggctt attgcggtcg tctttattct
    44161 ttacgatcaa atgacgccgc aggatattgt caatttcgat gtgcgcccgt ggtttgaaaa
    44221 aatggcgctc acccaacatc tcaccccatc acgctcacaa ggtctggaag cgatgattcg
    44281 cgcaattcgc gccaaagccg ctgcacttag ctaaactaaa gggacagctt tcatccggtt
    44341 ggctcacatt gtcgggtggt caatgtttac actggcctgc acaggagtgt tttggtttca
    44401 ggtgaactaa gcgccatccg acgtttcagc gtgagtctcc ggcaaataca ggaggtttac
    44461 aatgaaacgc gcgtctttgc ttacactcac gcttatcggc gcttttagcg ccatccaggc
    44521 tgcctgggcg gttgattatc cgctaccacc aaccggcagc cgactggttg ggcaaaatca
    44581 aacgtatacg gtgcaagaag gggataaaaa ccttcaggcc atcgcccgac gttttgatac
    44641 tgcggcaatg ttgatccttg aagccaataa cactatcgcc ccggtgccaa aacccggtac
    44701 gacgataact attccttcac aactgttatt acctgatgca ccgcgccagg ggataattgt
    44761 gaaccttgca gaactgcgcc tttattatta tccgccggga gaaaatatcg tgcaggttta
    44821 tccgataggt attggtttgc aggggctgga aacgccggtg atggaaacgc gtgtggggca
    44881 gaaaatccct aacccaacct ggacgcctac ggcgggcatt cgtcaacgtt cgctggagcg
    44941 tggcattaaa ttaccgccgg tcgttcctgc cgggccaaat aacccgctag gacgttacgc
    45001 actgcgcctc gcgcatggta atggcgaata cctcattcat ggcaccagtg cgccggacag
    45061 cgtcggtttg cgcgtcagtt cgggctgtat tcgcatgaat gcaccggata ttaaagcttt
    45121 attctccagc gtgcggacgg gaacgccggt gaaagtgatc aacgaaccgg tgaaatattc
    45181 cgtggaacct aacgggatgc gttatgttga agtacatcga ccactatcgg cagaagaaca
    45241 gcagaacgtt cagacaatgc cgtacacgct gccagcaggc tttacgcaat ttaaagacaa
    45301 taaggctgta gatcagaagt tagtcgataa agcgttgtat cgtcgggcag ggtatccggt
    45361 tgcggtgagc agtggagcaa ctcccgcagc cagcaatgcg ccttcagtag agtcagcgca
    45421 gaatggggaa ccagagcaag ggaatatgtt acgcgcgacg cagtagcggt aaatagcagg
    45481 caaaaaaatg gcgcacaatg tgcgccattt ttcacttcac aggtactatt acttgcggta
    45541 tttagtagcc atgttgtcca gacgctggtt agcacgagct gcgtcatctt tagcagcctg
    45601 aacgtcggaa cgcattgcgt tcacgtcgtt gctcagctgg tcaactttag cgttcagagt
    45661 ctgaacgtca gaagacagct gatcgatttt agcgttgctg gagcaacctg ccagcagagt
    45721 agaacccagg attaccgcgc ccagtaccag tttagtagct ttcattatta ataccctcta
    45781 gattgagtta atctccatgt agcgttacaa gtattacaca aagtttttta tgttgagaat
    45841 atttttttga tgggaaggca cttatttttg atcgttcgct caaagaagca tcgaacgctg
    45901 ggttttagat aaaaaaattg agagaaaaca ggatgcttcc atcggattca tcttagataa
    45961 agtgagatta tatagtgaaa tccgatttga ttttttattg cttctggtta tcgattaaat
    46021 aaaaaaagcg cccatcagga cgcttcgata tacaaattaa ttcacaaaag caatattaca
    46081 ggacgtgaac agatgcggtg ttagtagtgc cgctcggtac cagtgcacca gaaaccataa
    46141 ctacgacatc acctttgtgt gccagaccgc tctgcagagc cagttcttta cccagacggt
    46201 agaagtcatc agtagaagtg atctctttaa ccagctgcgg cacaacgcct ttgctcagta
    46261 ctaactggtg agccgttttt tcgttggtgg tcagtgccag gatggtggca tccgggaagt
    46321 atttacgtac tgcgcgagca gatttaccgc cctgagtagc aaccacgatc agcggagcat
    46381 ccagtttttc agcagtttca acggcaccac ggcataccgc ttcggttata cgcagtttac
    46441 ggttgtcatt gttgaactcg agacggctgt tcatcacgcg gtcggtacgt tcgcagatgg
    46501 tcgccatgat agaaaccgct tccagcgggt atttaccttt tgcggattca ccagacagca
    46561 tcactgcgtc agtaccgtcg aggatggcgt ttgcaacgtc accggcttct gcgcgagtcg
    46621 ggcgtgggtt tttgatcatg gaatccagca tctgggtcgc agtgataacg actttacgtg
    46681 cacggataca tttttcgatc atcatcttct gggcgaagat aacttcttct accgggattt
    46741 ctacacccag gtcgccacgc gcaaccatga tgccgtcaga ggcttcgagg atttcgtcga
    46801 agttgttgag gccttcctgg ttttcgattt tggagatgat gtggatgttt tcgccgccgt
    46861 gcgctttcag gtgctcacgg atttcgataa cgtcagaacg cttacgaata aaggaagcag
    46921 caacaaagtc tacgccttgt tcgcaaccaa agatcaggtc ctgtttgtct ttttcagcca
    46981 gtgctggcag ggcaatggaa acgccaggca ggttcacacc tttgttttcg cccaggtcgc
    47041 cgttgttcag cactttacag ataactttgt taccttcaat ggcggtaact tccataccga
    47101 tcagaccgtc gtcaaccagt acggtgttgc caacagacag gtcagtagtg aaaccttcat
    47161 acgttaccgc aaccatttcg ctgttgccga taacagattt atcagtagtg aaagtaaagg
    47221 tctgacccgc tttcagagaa acgtcgttac cgccttccag tttcatggtg cggatttccg
    47281 gacctttggt atcaagcagg atagcggcgg ttttaccagt tttgctcatc acgttgcgca
    47341 gattctgaat gcgctgaccg tgttctgcat agtcaccatg agagaagttc agacgcataa
    47401 cgttcatgcc agcgtccagc attttagcta acatctcttc agattcggtt ttcggtccga
    47461 tggtgcaaac aattttggtc tttttcatga cagtcttagt ctttaagttg agaaggatgg
    47521 gagaaacttg ctttctgggc gcactgccgg aaagcgaatc cggtattacg aaagtggttg
    47581 tgcctcgctc taaggatagg tgacatcgaa aaagcgtgca gaggaatgtg tgcttgtgtc
    47641 tcagcccaac gtgagtgcct gtttttgagt cgttgagttc tacagtccaa agtgctgaaa
    47701 ccattcaaga gtcaattggc gcgcattata cgctgaaatt aatccaaaag gaaaacaaaa
    47761 acagcgtttc aaaaaatata caacttgtta gacaataaat tgttatcaaa gattcagcgt
    47821 tccagggaaa aggttacgca aaaacttcgt tgtttgcgca acgtctggtg ccggggttgt
    47881 cagtgtgagg ataagtgaaa gttcatccgg tgtataaata
//
LOCUS       DAFGPF010000023        47913 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFGPF010000023 DAFGPF010000000
VERSION     DAFGPF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47913
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.023"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(1..258)
                     /locus_tag="LSX49_001552"
                     /pseudo
     CDS             complement(1..258)
                     /locus_tag="LSX49_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005010036.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(688..1356)
                     /locus_tag="LSX49_001553"
                     /pseudo
     CDS             complement(688..1356)
                     /locus_tag="LSX49_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313257.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1479..1931)
                     /gene="tabA"
                     /locus_tag="LSX49_001554"
     CDS             complement(1479..1931)
                     /gene="tabA"
                     /locus_tag="LSX49_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin biofilm protein TabA"
                     /protein_id="HBL7167981.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRL
                     FYLISEDMTEPYKARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPETDWLVDKDIAF
                     LPEVVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA"
     gene            complement(2076..2669)
                     /locus_tag="LSX49_001555"
     CDS             complement(2076..2669)
                     /locus_tag="LSX49_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313255.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7167982.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLAEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSLEQLCATAALAGEAIKTILKE"
     gene            2740..3453
                     /gene="bdcA"
                     /locus_tag="LSX49_001556"
     CDS             2740..3453
                     /gene="bdcA"
                     /locus_tag="LSX49_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7167983.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAA
                     ERLAHETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            3584..3979
                     /locus_tag="LSX49_001557"
     CDS             3584..3979
                     /locus_tag="LSX49_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBL7167984.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPEKQFEDIMTVKNEIFSAP
                     PYPNWTAVGVTWLAGFDFEIKVIARIPEL"
     gene            4260..4394
                     /gene="pyrL"
                     /locus_tag="LSX49_001558"
     CDS             4260..4394
                     /gene="pyrL"
                     /locus_tag="LSX49_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HBL7167985.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            4398..5333
                     /gene="pyrB"
                     /locus_tag="LSX49_001559"
     CDS             4398..5333
                     /gene="pyrB"
                     /locus_tag="LSX49_001559"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBL7167986.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            5346..5807
                     /gene="pyrI"
                     /locus_tag="LSX49_001560"
     CDS             5346..5807
                     /gene="pyrI"
                     /locus_tag="LSX49_001560"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HBL7167987.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            5880..6266
                     /gene="ridA"
                     /locus_tag="LSX49_001561"
     CDS             5880..6266
                     /gene="ridA"
                     /locus_tag="LSX49_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HBL7167988.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(6472..9168)
                     /gene="mgtA"
                     /locus_tag="LSX49_001562"
     CDS             complement(6472..9168)
                     /gene="mgtA"
                     /locus_tag="LSX49_001562"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBL7167989.1"
                     /translation="MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTAVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(9309..9362)
                     /gene="mgtL"
                     /locus_tag="LSX49_001563"
     CDS             complement(9309..9362)
                     /gene="mgtL"
                     /locus_tag="LSX49_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HBL7167990.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            9547..10494
                     /gene="treR"
                     /locus_tag="LSX49_001564"
     CDS             9547..10494
                     /gene="treR"
                     /locus_tag="LSX49_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HBL7167991.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            10613..12034
                     /gene="treB"
                     /locus_tag="LSX49_001565"
     CDS             10613..12034
                     /gene="treB"
                     /locus_tag="LSX49_001565"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HBL7167992.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGNFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            12084..13739
                     /gene="treC"
                     /locus_tag="LSX49_001566"
     CDS             12084..13739
                     /gene="treC"
                     /locus_tag="LSX49_001566"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBL7167993.1"
                     /translation="MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHK
                     LGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR
                     NDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALA
                     DESSVFYTYQKLIALRKQEAILTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRE
                     IQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK"
     gene            14133..16271
                     /gene="nrdD"
                     /locus_tag="LSX49_001567"
     CDS             14133..16271
                     /gene="nrdD"
                     /locus_tag="LSX49_001567"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBL7167994.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWSIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            16430..16894
                     /gene="nrdG"
                     /locus_tag="LSX49_001568"
     CDS             16430..16894
                     /gene="nrdG"
                     /locus_tag="LSX49_001568"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HBL7167995.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QTFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVKRIRAECPGKDIW
                     VWTGYKLDELNAAQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR"
     gene            complement(16939..17325)
                     /gene="cybC"
                     /locus_tag="LSX49_001569"
     CDS             complement(16939..17325)
                     /gene="cybC"
                     /locus_tag="LSX49_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HBL7167996.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVIEKADN
                     AAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNAYHQKYR"
     gene            complement(17508..18860)
                     /gene="pmbA"
                     /locus_tag="LSX49_001570"
     CDS             complement(17508..18860)
                     /gene="pmbA"
                     /locus_tag="LSX49_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HBL7167997.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFL
                     LDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            18954..19505
                     /locus_tag="LSX49_001571"
     CDS             18954..19505
                     /locus_tag="LSX49_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HBL7167998.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            complement(19656..21029)
                     /gene="mpl"
                     /locus_tag="LSX49_001572"
     CDS             complement(19656..21029)
                     /gene="mpl"
                     /locus_tag="LSX49_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HBL7167999.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            21205..22203
                     /gene="fbp"
                     /locus_tag="LSX49_001573"
     CDS             21205..22203
                     /gene="fbp"
                     /locus_tag="LSX49_001573"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HBL7168000.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA"
     gene            complement(22236..23231)
                     /gene="yjfF"
                     /locus_tag="LSX49_001574"
     CDS             complement(22236..23231)
                     /gene="yjfF"
                     /locus_tag="LSX49_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease YjfF"
                     /protein_id="HBL7168001.1"
                     /translation="MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPIYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQR"
     gene            complement(23218..24240)
                     /locus_tag="LSX49_001575"
     CDS             complement(23218..24240)
                     /locus_tag="LSX49_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7168002.1"
                     /translation="MPQSLPDTTPPKRRFRWPTGMPQLAALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITAGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVLTLLLFWLLTRKTALGMFIEAVGINIRAAKNAG
                     VNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RSHDKT"
     gene            complement(24254..25756)
                     /locus_tag="LSX49_001576"
     CDS             complement(24254..25756)
                     /locus_tag="LSX49_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL7168003.1"
                     /translation="MTTDQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGEN
                     GAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFGLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVL
                     RNGSFVGCRETRELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKPQTLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            complement(25896..26852)
                     /gene="ytfQ"
                     /locus_tag="LSX49_001577"
     CDS             complement(25896..26852)
                     /gene="ytfQ"
                     /locus_tag="LSX49_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HBL7168004.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            27162..27692
                     /gene="ppa"
                     /locus_tag="LSX49_001578"
     CDS             27162..27692
                     /gene="ppa"
                     /locus_tag="LSX49_001578"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HBL7168005.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLVAVPHSKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            complement(27772..28122)
                     /gene="chpB"
                     /locus_tag="LSX49_001579"
     CDS             complement(27772..28122)
                     /gene="chpB"
                     /locus_tag="LSX49_001579"
                     /EC_number="4.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease toxin ChpB"
                     /protein_id="HBL7168006.1"
                     /translation="MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLG
                     MTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAADE
                     VVEEALLRLQAVVE"
     gene            complement(28116..28367)
                     /gene="chpS"
                     /locus_tag="LSX49_001580"
     CDS             complement(28116..28367)
                     /gene="chpS"
                     /locus_tag="LSX49_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin ChpS"
                     /protein_id="HBL7168007.1"
                     /translation="MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILT
                     PISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGDEIW"
     gene            complement(28579..28920)
                     /locus_tag="LSX49_001581"
     CDS             complement(28579..28920)
                     /locus_tag="LSX49_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HBL7168008.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            complement(28923..32702)
                     /gene="tamB"
                     /locus_tag="LSX49_001582"
     CDS             complement(28923..32702)
                     /gene="tamB"
                     /locus_tag="LSX49_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HBL7168009.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVP
                     GLDIGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPEEKPLGETLKDLFSR
                     PVLPEMTDVHLPLNLNIEEFKGEQLRVTGDTDITVRTMLLKVSSIDGNTKLDALDIDS
                     SQGIVNASGTAQLSDNWPVDITLNSTLNVEPLKGEKLKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQLYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGQEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEFPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVNI
                     NLVTLNAKGSEKQHELQLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVTDPQGRRNLGGNVNIRNFNLAMINPIF
                     NRGEKAAGMVSANLRLGGDVQSPQLFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEPKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            complement(32699..34432)
                     /gene="tamA"
                     /locus_tag="LSX49_001583"
     CDS             complement(32699..34432)
                     /gene="tamA"
                     /locus_tag="LSX49_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HBL7168010.1"
                     /translation="MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKARETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQTLDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGT
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            34638..35276
                     /gene="msrA"
                     /locus_tag="LSX49_001584"
     CDS             34638..35276
                     /gene="msrA"
                     /locus_tag="LSX49_001584"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL7168011.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            35599..36942
                     /locus_tag="LSX49_001585"
     CDS             35599..36942
                     /locus_tag="LSX49_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL7168012.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANM
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(37004..37210)
                     /locus_tag="LSX49_001586"
     CDS             complement(37004..37210)
                     /locus_tag="LSX49_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HBL7168013.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            37535..38092
                     /locus_tag="LSX49_001587"
     CDS             37535..38092
                     /locus_tag="LSX49_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HBL7168014.1"
                     /translation="MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEKSSAVVVLDKDGRVQ
                     WAKDGALTQEEVQQVMDLLHKLINK"
     gene            complement(38082..38822)
                     /gene="cysQ"
                     /locus_tag="LSX49_001588"
     CDS             complement(38082..38822)
                     /gene="cysQ"
                     /locus_tag="LSX49_001588"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HBL7168015.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNVMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
     gene            39012..40955
                     /gene="cpdB"
                     /locus_tag="LSX49_001589"
     CDS             39012..40955
                     /gene="cpdB"
                     /locus_tag="LSX49_001589"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HBL7168016.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDIHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     LVVVLAHSGLSADPYKVMAENSVYYLSEIPGVDAIMFGHAHAVFPSKDFADIEGADIA
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARPIYDIANKKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPNSTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMINANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKG
                     QYPMNKVATDDIGFAIYQVDLSK"
     gene            complement(41084..41464)
                     /locus_tag="LSX49_001590"
     CDS             complement(41084..41464)
                     /locus_tag="LSX49_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL7168017.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIAYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            41553..42413
                     /gene="qorB"
                     /locus_tag="LSX49_001591"
     CDS             41553..42413
                     /gene="qorB"
                     /locus_tag="LSX49_001591"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HBL7168018.1"
                     /translation="MIAITGATGQLGHYVIESLMKTVPASQIVAIVRNPAKAQALAAQ
                     GITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKAAGVKFIAYT
                     SLLHADTSPLGLADEHIETDKMLADSGIVYTLLRNGWYTENYLASAPAALEHGVFIGA
                     AGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKSVT
                     YQNLSEADFAAALKSVGLPDGLADMLADSDVGASKGGLFDNSKTLSKLIGRPTTTLAE
                     SVSHLFNVNN"
     gene            42521..43486
                     /locus_tag="LSX49_001592"
     CDS             42521..43486
                     /locus_tag="LSX49_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709987.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBL7168019.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLASVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNIQ
                     TPDFSLPFGPRPLVFISLMVAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLLRQQMPPLMTLSGIALLVIGVVIAVRAKPEKPLTESVSES"
     gene            43594..44256
                     /gene="ytfE"
                     /locus_tag="LSX49_001593"
     CDS             43594..44256
                     /gene="ytfE"
                     /locus_tag="LSX49_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HBL7168020.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALA
                     GE"
     gene            complement(44301..45713)
                     /gene="cycA"
                     /locus_tag="LSX49_001594"
                     /gene_synonym="dagA"
     CDS             complement(44301..45713)
                     /gene="cycA"
                     /locus_tag="LSX49_001594"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HBL7168021.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(46022..46642)
                     /gene="fklB"
                     /locus_tag="LSX49_001595"
     CDS             complement(46022..46642)
                     /gene="fklB"
                     /locus_tag="LSX49_001595"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL7168022.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            46861..47499
                     /gene="ytfB"
                     /locus_tag="LSX49_001596"
     CDS             46861..47499
                     /gene="ytfB"
                     /locus_tag="LSX49_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YtfB"
                     /protein_id="HBL7168023.1"
                     /translation="MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIILVV
                     GFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQ
                     ESQPEEQPQTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
                     GAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR"
     gene            complement(47483..>47913)
                     /locus_tag="LSX49_001597"
     CDS             complement(47483..>47913)
                     /locus_tag="LSX49_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7168024.1"
                     /translation="KALDFSDLPPQKAIEKIIDFTWDYYISNPWFLKIVHSENQSKGV
                     HYAKSQRLLEINHAHLQLMESLLDEGKKQNIFKPDIDPLQVNINIAALGGYYLINQHT
                     LGLVYHISMVSPQALEARRKVIKETILSWLLVDPSSTAHE"
BASE COUNT        11796 a        12741 c        11892 g        11484 t
ORIGIN      
        1 ccataaacat atcctaactc attaagatac atctgttctc cctcataact cttaagtaat
       61 tgatagaagt accacttagc aaaatcaggt tgcttcatga aaaaatcctt caaaaaaaat
      121 atcattcact aaaatactga gaggcacttt atcaaaaacc aatttaacat catcaaatag
      181 ccttagtatt aagcgcgatt tttcttgatt acttaaatta aaatcattga catatacaac
      241 caacttctcc caaatcaatt cctgtaactc agggctgttt ttatagggtt ctttattgag
      301 gttgaaaaat aatgtctcag ctattttaga ctgatcgcag ttaaaatcaa tatgatcgat
      361 cacggagcgg gcatgcttta tctttgtagt atcatcagaa tattgcatac tttgattaaa
      421 acaccactcc agaattttta catcattaat atatggcaat tttaaaaaag tcttcaacat
      481 cgaatcgatg accttttcga gattaacttt tgcatcatct aaggaatcaa taagaatatt
      541 agacaggtta attttgatgt tattaatttc atcattacct tctgtaccac tagcaattct
      601 ggtatcatgt aacgttttca gatcatttat ttcttcaagt ataccacctt cgcctagtaa
      661 gtatggaatc gtgtcatcac atacatgagg cattaatagc agatgttctt tctttatttt
      721 ttctaatgta ctggctaatg gcttttctaa taactcgtta taatcaattg cgtccttcca
      781 gttcaactga tgattattta atagaagcgc catattcttg ttagcttcac gttggtaaca
      841 cgccagaacc ttgttagtaa tcaggtgtaa tgaactatca tcttttcttt caaaagactt
      901 accttcataa cgaaaactca aaaaatcaga ttgtggaaat ataatggctg tatgtccttg
      961 acgagtcccc atagtagtgg tagtagaaag tgaaatttct ataatcacct tagatgaatc
     1021 cgcacgctca ccttcaggat tattcataac aaaattcatt atttcactgc catcattatt
     1081 tttgatataa gatgaggact caatatgagc catcatattt ctacccgctt cgttggagca
     1141 tttgctaaaa tccacataac ccagggtaaa tatttttgcc aaaaactcca aaaatgctcc
     1201 aggagataga atattccttc tgctatcctg cccctcggca ttacgagcaa aatcattcat
     1261 tcccacacac caggtattta agacttcatt ttttggttta acattgtcgg ctgatgccat
     1321 gtgttgataa caattcaaat ctgatatttt tgccatgacg aactccttga gttaataaga
     1381 acgtctaagc attacaaatt ttactcacaa aaaaatatca aaaatcgctc ttttcacaaa
     1441 ctcgccgtaa acctggagtt atttacggcg aaaagtcatc acgccatcag catcttcact
     1501 actgctttgc gaacctgggc tggtgcaccc actgcgcaca gcggtttatg cacttccccc
     1561 ggataaaaca caacaaaatc accttcattc aggataactg ttttctcatc aacgacttcc
     1621 ggcaaaaatg cgatgtcttt atctactaac cagtcggtct ccggcgtacc tgcaggttgt
     1681 gtgctgaagg tcatgccttc ctgacctttt aacacaatct gaatgtcgag ataacgggca
     1741 tggtactccg cacggcgagc tttgtacggc tcggtcatat cttccgagat aagataaaac
     1801 agacgattgc cttcgatatc gtgcttaccc tttggcgttt ctgccgtaac gtgtgctttg
     1861 atatgctcaa tcgcctggcg taactcctgg ggtagccatg gctgaagatt atgaatattt
     1921 ccgatgatca tcttttccac tccttaatta aaacaatgtt tcatttccac cgttatacga
     1981 aaagatgatc aattccgcca gccttaacgc gtgaattatt gtcttatcac aacttatcgg
     2041 caggcgcgtt cccgcctttc ggatcaaggt cagcatcact ccttgagaat agtttttatc
     2101 gcttcccccg ccagtgcagc tgttgcacag agttgttcga gggagtgccc ctctcgtgcc
     2161 ttcgcagaaa gccctgacat cacggtactc ataaaatcag tcacacattg tgcgctttgt
     2221 ggatgccgcc tggcgatata gtcataaatg gtcgtttctg cggcgtgata atattgaacg
     2281 gcaatatcac gcgcttgtgg atcatgacta tgaatgcctt caagaaccat acagccagcg
     2341 cagccgccgt tttggctata tctgcgcgcc gcttctttta atacctcagc caggcactcc
     2401 cctaccggac gatcatcacg aagaatatcg gcaagcggaa tagcttccgt accgacatat
     2461 tcattgagta cacggctaaa taacccagcc ttactgccaa aagccgcgta gagactcggg
     2521 gggttaatac caagataatc agtaacttca gcaacactga cagcatcgaa acctttttgg
     2581 tgaaaaagca cttttgccgc agagactgcc tgctcaggag cgaaacgtct gggacgacct
     2641 ggaacgcgag attgtttttt agtgaccatt acaaaacttg ttgacagaaa gttaaaacag
     2701 ttttgtaatg catgttacat aataaatcaa ggagtcctta tgggcgcttt tacaggtaag
     2761 acagttctca tcctcggtgg tagccgtgga ataggtgccg ctatcgtacg tcgtttcgtc
     2821 accgatggag ccaatgtacg attcacctat gcggggtcga aagatgccgc tgaacgcctg
     2881 gcacatgaga ctggagcgac agcagtattc acagatagtg ctgacagaga cgctgttatt
     2941 gatgtcgttc gtaagagcgg cgcattggat atcctggtgg taaatgcagg tattggcgtc
     3001 tttggcgatg ccctggaatt aaatgccgac gatattgatc gccttttcaa aatcaatatt
     3061 catgcccctt accatgcctc tgttgaagcc gcccggcaga tgcccgaagg cgggcgcatc
     3121 ttaatcatcg gctccgtgaa tggcgatcgt atgcctgttg caggcatggc tgcttatgcc
     3181 gccagtaaat ctgccctgca aggcatggcg cgcgggctgg cccgtgattt tggaccgcgt
     3241 gggatcacca tcaacgtcgt ccagccaggg ccaatagata ccgacgctaa tcccgccaac
     3301 gggccaatgc gcgatatgtt gcatagtttt atggctatca aaagacatgg gcaaccggaa
     3361 gaggtcgctg gaatggtcgc atggttagca gggccagaag ccagttttgt taccggcgcg
     3421 atgcatacca ttgatggcgc gtttggggca taaccgacta cgctcaatta agcccagcca
     3481 ttatccatga tgtctgggtt ttgtttactc acgtcgttcc ctaaaagcgg ctcccggtaa
     3541 atataaatct tctgttcatg tcgtaaatct tgaggataac caaatggtag aaagaaccgc
     3601 tgttttccct gctggccgac attcactgta tgctgaacat cgttattcgg cggctattcg
     3661 ttccggcgat ttgctgtttg tttccgggca agtaggaagt cgagaggacg gaacaccaga
     3721 acccgatttt cagcaacaag tcagactggc atttgataat ttgcatgcga ccctggcagc
     3781 tgcgggatgc acttttgacg atatcattga tgttacgagc tttcataccg atccggaaaa
     3841 acaatttgaa gacatcatga cggtcaaaaa tgaaatattt agcgcccctc cttatccaaa
     3901 ctggacggcg gtgggcgtta cctggctggc aggctttgat tttgaaatta aagtgatagc
     3961 gcgcatccct gagctgtaag caatagtgtt agccgttcgt tttcacactc cgccgtataa
     4021 gtcggatgaa tggaataaaa tgcatatctg attgcgtgaa agtgaaaaag aaaaaagcag
     4081 gaaatgtctg caattattga taccgaacga cagttctctt ccagaatcaa agcaaataaa
     4141 aatgcataca ttttgacttt taattcaaat aaaccgtttg cgctgacaaa atattgcatc
     4201 aaatgcttgc accgcttctg gctatgagta taatgccgga caatttgccg ggaggatgta
     4261 tggttcagtg tgttcgacat tttgtcttac cgcgtctgaa aaaagacgct ggcctgccgt
     4321 ttttcttccc gttgatcacc cattcccagc ccctcaatcg aggggctttt ttttgcccag
     4381 gcgtcaggag ataaaagatg gctaatccgc tatatcagaa acatatcatt tccataaacg
     4441 accttagtcg cgatgacctt aatctggtgc tggcgacagc ggcgaaactg aaagcaaacc
     4501 cgcaaccaga gctgttgaag cacaaagtca ttgccagctg tttcttcgaa gcctctaccc
     4561 gtacccgcct ctctttcgaa acatctatgc accgcctggg tgccagcgtg gtgggcttct
     4621 ccgacagcgc caatacatca ctgggtaaaa agggcgaaac gctggccgat accatttcgg
     4681 ttatcagcac ttacgtcgat gcgatagtga tgcgtcatcc gcaggaaggt gcggcgcgcc
     4741 tggccaccga gttttccggc aatgtaccgg tactgaatgc cggtgatggc tccaaccaac
     4801 atccgacgca aaccttgctg gacttattca ctattcagga aacccagggg cgtctggaca
     4861 atctccacgt cgcaatggtt ggtgacctga aatatggccg caccgttcac tccctgactc
     4921 aggcgttagc gaagttcgac ggcaaccgtt tttacttcat cgcgccggac gcgctggcaa
     4981 tgccgcaata cattctggat atgctcgatg aaaaagggat cgcatggagt ctgcacagct
     5041 ctattgaaga agtgatggcg gaagtagaca tcctgtacat gacccgcgtg caaaaagagc
     5101 gtctggaccc gtccgagtac gccaacgtga aagcgcagtt tgttcttcgc gccagcgatc
     5161 tccacaacgc caaagccaat atgaaagtgc tgcatccgct gccgcgtgtt gatgagattg
     5221 ccaccgatgt ggataaaacg ccacacgcct ggtacttcca gcaggcaggc aacgggattt
     5281 tcgctcgcca ggcgttactg gcactggttc tgaatcgcga tctggtactg taaggggaaa
     5341 tagagatgac acacgataat aaattgcagg ttgaagctat taaacgcggc acggtaattg
     5401 accatatccc cgcccagatc ggttttaagc tgttgagtct gttcaagctg accgaaacgg
     5461 atcagcgcat caccatcggt ctgaacttgc cttctggcga gatgggccgc aaagatctga
     5521 tcaaaatcga aaataccttt ttgagtgaag atcaggtaga tcaactggca ttgtatgcgc
     5581 cgcaagccac ggttaaccgt atcgacaact atgaagtggt gggtaaatcg cgccccagtc
     5641 tgccagagcg catcgacaat gtgctggtct gcccgaacag caactgtatc agccatgccg
     5701 aaccggtttc ttccagcttt gccgtgcgaa aacgcgccaa tgacatcgcg ctcaaatgca
     5761 aatactgtga aaaagagttt tcccataatg tggtgctggc caattaattg cggttggtaa
     5821 taaaagtctg gctccctata atgagccaga ctttttaccg ctgtaataaa ggagaaatca
     5881 tgagcaaaac tatcgcgacg gaaaatgcac cggcagctat cggtccttac gtacagggcg
     5941 ttgatctggg caatatgatc atcacctccg gtcagatccc ggtaaatccg aaaacgggtg
     6001 aagtaccggc agacgtcgct gcacaggcac gtcagtcgct ggataacgta aaagcgatcg
     6061 tcgaagccgc tggcctgaaa gtgggcgaca tcgttaaaac caccgtgttt gtgaaagatc
     6121 tgaacgactt cgctaccgtt aatgctacct acgaagcctt cttcaccgaa cacaacgcca
     6181 ccttcccggc acgttcttgc gttgaagtcg cccgtctgcc gaaagacgtg aagattgaga
     6241 tcgaagcgat cgctgttcgt cgctaatctt gatggaaatc cgggctatca tgcccggatt
     6301 aagtctgatg acaaacgcaa aatcgcctga tgcgctacgc ttatcaggcc tacgtgattc
     6361 ctgcaattta ttgaatttgt tggccggata aggcatttac gccgcatccg gcatgaacaa
     6421 agcttacttt gtctgcaatc tgaatcgggg ctatcgtgcc cagtttattc tttattgcca
     6481 gccgtaacga cggctataga accctttcac caactgggtt aatgtcatat accctgccag
     6541 aatcgcaacc agccacggga aatagcttaa cggcagcgcc tgtaattgca gataactggc
     6601 cagcggtgaa aacggcaatg cgatcccgac aatcatcacg atcacggtca tgatcattaa
     6661 cggccacgat gcacagctct gaataaacgg cacacggcgg gtgcggatca tatgcacaat
     6721 cagcgtttgc gacagtaagc ccaccacaaa ccatcccgac tggaacagcg tttgcgtttc
     6781 cggcgtgttg gcatggaata cccaccacat caggcaaaac gtcagaatat cgaagatcga
     6841 gctgatcggt ccgaagaaga tcataaagcg ccccagatcc gccgggttcc aacgctgcgg
     6901 cttttgaatt tgctcgtcgt cgacgttatc aaacgggatc gccacctgtg acacatcata
     6961 cagcaggttc tgaataagca agtgtaacgg caacatcggc aggaagggca agaaagcact
     7021 cgccaccagc acgctgaaca cattaccgaa gttggagctc gccgtcattt tgatgtattt
     7081 cagcatgttg gcgaaagtgc gacgtccttc aataaccccc tcttccagca ccatcaggct
     7141 tttttccagc aggatgatat cagccgcttc acgggcaata tctaccgcgc cgtccacaga
     7201 aatgccgata tccgcagcgc gtaaggcggg cgcatcatta ataccatcgc ccataaagcc
     7261 aaccacatgc ccttcgcgct tcagtaaggt cacaatgcgt tctttatgca tcggcgtcag
     7321 acgagcaaac agcgtggtac gctgtgcgag atttgccagt tcgtcgtcag atagcgtttc
     7381 aatatcacta ccaatgacca cctctcccgc gtccagcccc acttcatggc acactttcgc
     7441 tgcaactaac tcactgtcgc cagtaaggat ttttacggta attccactcg cttttaatgc
     7501 cttcagtgcc ggagcagttg tctctttcgg cggatcaagg aaagcaatat atccttcgag
     7561 gatcaggtcg gattcatccg cccgctggta atctccttca cgcgctggca ggtatttcgt
     7621 cgccaccgca accacgcgca gcccctgacg attcagcgta tcagtaaccc gcttaatctt
     7681 acgcagcatg atgtcatcga gcggcacaat ctcgccattg tgacgcacct gcgaacacac
     7741 attgaggatt tcctgcaatg cacctttgca aaccagctga tggtgctcgg tattttctgc
     7801 cactaccacc gacatccggc gacgctcgaa atcaaacgga atctcatcga ttttttgcca
     7861 acgactggcc agcgagcgcg ctgactcttc atccgtacct tcgagcaccg ctgtatcgag
     7921 caggttttta agtccggtct gataatgact gttcaaccac gcgctatgca gcacgcgttc
     7981 gctggtttta ccggagatat cggtatgatt ctccagcaca attttgtcct gtgtcagggt
     8041 gccagtttta tcagtgcaca gaatatccat tgcgccaaag ttctgaatag catccagatg
     8101 tttgacgatc actttctgtt tcgacagctt tactgcgccg cgcgccagcg tcgaggtaac
     8161 aatcatcggc aacatttccg gcgttaagcc taccgcgacc gaaagcgcaa acagtgccgc
     8221 ttcccaccag tcgcctttgg tgtaaccatt gattaacagc accaccggag ccatcaccag
     8281 cataaagcga atcagcagca tactgacgcg gctgatccct tgctgaaagg cattcggctc
     8341 gctttcctgc tcactaacac gccccgccag ttgaccaaac caggtattgg cacctgtagc
     8401 aatcaccatt gcttgtgccg tgccgctcac cacggtggtg cccataaaac acagggtgtc
     8461 gcactccagc ggattgctgt gctccggctg gcgagtggta gctgcttttt ctacgggcag
     8521 agactcaccg gttaacgacg cctgagcgac gaacagatcc cgcgcctgca agatacgtaa
     8581 atctgccggg atcatatccc ccgccgccag ttttataata tcgccgggca ccagctggtc
     8641 gatcgggatc tccagccagc cattttcgcc tttgtcgtta attacgcgca gcaccgtcgc
     8701 agtattgctg accatcgctt tcagggcatc tgccgcttta gtggaacgtg cttcctgaat
     8761 aaagttcagc aacgtagaaa tagcgaccat tagcgcgata acgcccgcgg caaataaatc
     8821 ttccgtggcg taagaaatag cgccgagaat ggtgagtaaa atattaaatg ggttgcgata
     8881 gcagacccat aaatgtaccc accacggcga cggttgttgt gcgggtaatt tattttcacc
     8941 atgttgttcg cgggcagatt ccacttccgc ctgatttaac ccttccggat gggtgtcgaa
     9001 cgttttccat aattcttctt cgggcatcac cgccattttc aggcaatgcg cacttaagga
     9061 cggcgggacc gccgtattca ctgtctgctg cgcgccaggc aatggatcgc gatgaaccag
     9121 acgggaaggt aaatggcgaa tgagccgggt aaaaatttct ttaaacataa ggagtccctc
     9181 cgcactgtct gaaacagtac agaaatgtct tcaggcgtgg cgaagcctta cctgaaggta
     9241 ataaagctga gcagggacgt taaaacgtca cggccttacg catccggtaa cgccgtgaaa
     9301 agacgggctt accggaaaag ttttaatctc cgtcgaggga gaggcgtggg atcaggttcc
     9361 atataacctc cggtaagtga aaaaagcgcc gcaaataata aggagaatcc aataatattc
     9421 gtagcatcta tggcgatata atacctgctg gcaactaaac caacgataaa ccagacttta
     9481 cccattgctg aatgcacggg taaagttagg ctcaaataat taaacaacac gttacaggac
     9541 aacaggatgc aaaatcggct gaccatcaaa gacatcgcac gcttaagcgg cgtggggaaa
     9601 tctacagttt cccgggtgct gaataacgaa agcggcgtga gccagcgcac ccgcgagcgt
     9661 gttgaagcag tgatgaatca gcatggattt tccccttccc gctctgcgcg cgctatgcgt
     9721 gggcaaagcg ataaagtggt cgccatcatt gttacccgtc tggattcgtt gtcagaaaat
     9781 ctcgccgttc aaaccatgct gccagcgttc tatgaacaag gttacgaccc aatcatgatg
     9841 gaaagtcagt tttccccaca attagttgcc gaacatttgg gggtgctgaa acggcgtaat
     9901 atcgacggcg tagtgctgtt cggttttact ggcataacag aagaaatgtt agcccactgg
     9961 cagtcatcgc tggttctgct ggcgcgtgac gcaaaaggct ttgcttcggt ctgttatgac
    10021 gacgaagggg caatcaagat cctgatgcaa cggctgtatg accaggggca tcgtaatatc
    10081 agttatctcg gcgtgccgca tagtgacgtg acaaccggta agcgacgtca cgaagcctac
    10141 ctggcgttct gcaaagcgca taaactgcat cccgttgccg ctctgccagg gcttgctatg
    10201 aagcaaggct atgagaacgt ggcaaaagtg attacgcctg aaactactgc gttactgtgc
    10261 gcaaccgaca cgctggcact tggcgcaagt aaatacctgc aagagcaacg catcgacacc
    10321 ttgcaactgg cgagcgtcgg taatacaccg ttaatgaaat tcctccatcc ggagatcgtc
    10381 accgtagatc ccggttacgc cgaagctgga cgccaggcgg cctgccaatt gatcgcacag
    10441 gtaaccgggc gcagcgaacc gcaacaaatc atcatccccg ccaccctgtc ctgatcgttt
    10501 cctgaacgat aaattgtgat cttcgctgcg tttcgggaac gttcccgttt ttaaattttt
    10561 ccgcgcaata tattctgcag ccaaccaaaa atgtcatctg ccatggggct ttatgatgag
    10621 caaaataaac caaacggata tcgatcggtt gattgaactg gtcggcgggc gcggcaatat
    10681 tgcgacggtg agccactgta ttactcgcct gcgctttgtc ctcaaccaac cggccaatgc
    10741 cagaccgaaa gaaattgagc aactccccat ggtgaaaggc tgtttcacca atgccgggca
    10801 atttcaggtg gtgattggca ccaatgtggg tgattactat caagcactga ttgcgtcaac
    10861 cggacaggcg caggttgata aagagcaggt aaaaaaagcc gcccggcaga atatgaaatg
    10921 gcatgagcag ttgatctctc atttcgcgga gatcttcttc ccgctgctgc ccgcgttgat
    10981 tagcggcggt ttgatcctcg gttttcgcaa tgtgatcggc gatttgccca tgagcaacgg
    11041 tcagacgctg gcgcaaatgt acccttccct gcaaacgatc tacgattttc tgtggttgat
    11101 cggtgaagcg atcttcttct acctgccggt cggtatttgc tggtcagcgg tgaaaaaaat
    11161 gggcggcacg ccgatccttg gtatcgtgct tggcgtgaca ctggtttctc cccagctgat
    11221 gaacgcttat ctgctcgggc agcagctgcc ggaagtgtgg gactttggca tgttcagcat
    11281 cgccaaagta ggctatcagg cgcaggtgat cccggcactg ttagccgggc tggcgctggg
    11341 cgttattgaa actcgcctta aacgcatcgt gccggattac ctctatctgg tggtggtacc
    11401 cgtctgttcg ctgatcctcg cggtgttcct cgcccatgcg ctgattggtc cgtttggtcg
    11461 catgattggc gatggcgttg cctttgcggt acgtcacctg atgaccggca actttgctcc
    11521 gattggtgcg gcattgtttg gcttcctgta cgcgccgctg gtgatcaccg gcgtacacca
    11581 gaccaccctt gctattgatt tgcagatgat tcaaagcatg ggtggcacgc cagtgtggcc
    11641 gctgattgcg ctgtcgaata tcgctcaggg ctccgccgtg ataggcatta tcatttccag
    11701 ccgcaagcac aatgaacgcg agatctccgt gcctgccgct atctccgcct ggcttggggt
    11761 cactgagcct gcaatgtacg gcatcaacct gaaatatcgc ttcccgatgc tgtgcgcgat
    11821 gattggttct ggtctggcag gattgctatg cggcctgaac ggcgttatgg cgaatggcat
    11881 cggcgtaggc ggcctgccgg gaattctctc gattcaaccg agctactggc aggtatttgc
    11941 gctggcaatg gctatcgcca tcatcatccc gattgtactc acctcgttta tctatcagcg
    12001 gaaataccgc ctgggcacgc tggacattgt ttaattttct tcggggcgca attgcgcccc
    12061 ctcgcatttg caggaataac gtaatgacta atcttcccca ctggtggcaa aacggcgtta
    12121 tctaccagat ttatccaaag agttttcagg acaccacggg tagcggcacc ggcgatttac
    12181 gtggcgttat ccaacgcctg gactatctgc ataaactggg cgttgatgcc atctggctaa
    12241 ccccctttta tgtctctccc caggtcgata acggttacga tgtagcgaac tatacggcga
    12301 ttgatcccac ctacggcacg ctggacgatt ttgacgaact ggtgacgcag gcaaaatcgc
    12361 gcgggattcg tatcattctc gatatggtgt ttaaccatac ctctacccaa catgcctggt
    12421 ttcgcgaggc gctgaacaaa gaaagccctt accgccagtt ttatatctgg cgcgatggcg
    12481 aaccagaaac gccaccgaac aactggcgtt caaaatttgg cggtagtgcg tggcgctggc
    12541 atgcggaaag cgaacagtac tatttgcatc tctttgcacc agaacaggcg gatctcaact
    12601 gggagaatcc agcggtacgc gcagagctga aaaaagtctg tgaattctgg gccgatcgtg
    12661 gggtcgacgg gttgcgcctg gatgtggtga atctgatctc caaagacccg cgtttccctg
    12721 aagacctgga tggcgacggg cgtcgcttct acaccgacgg gccacgagca cacgagtttt
    12781 tgcacgagat gaaccgcgat gtgtttacgc cacgcgggtt aatgaccgta ggtgaaatgt
    12841 cctccaccag ccttgagcat tgccagcgat acgcggcact gacaggcagt gaattgtcga
    12901 tgacctttaa ttttcatcac ctgaaggtcg attatcccgg tggtgaaaaa tggacgctgg
    12961 ctaaacctga ctttgtggcg ttgaaaacat tgttccgcca ctggcaacaa ggaatgcaca
    13021 acgtggcatg gaatgccttg ttctggtgta accacgatca gccgcgcatt gtttctcgct
    13081 ttggtgatga aggtgaatac cgcgtgcctg cggcaaaaat gctggcgatg gtgctgcatg
    13141 gcatgcaggg aacgccgtat atctaccagg gcgaagagat tggcatgacc aacccgcatt
    13201 tcacgcgcat tactgactat cgcgacgtgg agagcctcaa tatgtttgcc gagctgcgca
    13261 acgatggtcg tgatgccgac gagttattgg caatcctcgc cagtaaatcc cgtgacaaca
    13321 gccgcacgcc catgcaatgg agcaacggcg ataatgccgg gtttacggct ggcgaaccgt
    13381 ggattggcct gggcgataac tatcaacaaa tcaacgtaga agccgcgctg gccgatgagt
    13441 cctcggtgtt ttacacctac caaaagttaa tcgcactgcg taagcaagaa gccatcctga
    13501 catggggcaa ttaccaggat ctgctgccaa acagccctgt attgtggtgc tatcgccgtg
    13561 aatggaaggg gcaaaccttg ctggtcattg ccaaccttag ccgtgagatc caaccctggc
    13621 agccagggca aatgcgcggc aactggcagc ttgtgatgca taactacgaa gaagcctcac
    13681 cacaaccctg tgccatgaat ttacggcctt ttgaggctgt ctggtggtta cagaagtaaa
    13741 tcttccctaa gccccggtaa tgccggtcat tccggggttt tgtctgtcag catgttgttt
    13801 ttgttgattt ttcaaccagc aaattcatta aaaaatttac ataacgctgt agcgcccgtc
    13861 atccgtacgc tctgcttttt actttgagct acatcaaaaa aagttaaaac atccttgatg
    13921 caaagcacta tatatagact ttaaaatgcg tcccaaccca atatgttgta ttaatcgact
    13981 ataattgcta ctacagctcc ccacgaaaaa ggtgcggcgt tgtggataag cggatggcga
    14041 ttgcggaaag caccggaaaa cgaaacgaaa aaaccggaaa acgcctttcc caatttctgt
    14101 ggataacctg ttcttaaaaa tatggagcga tcatgacacc gcatgtgatg aaacgagacg
    14161 gctgcaaagt gccgtttaaa tcagagcgca tcaaagaagc gattctgcgt gcagctaaag
    14221 cagcggaagt cgatgatgcc gattattgcg ccactgttgc cgcggttgtc agcgagcaga
    14281 tgcagggccg caaccaggtg gatatcaacg agatccagac cgcagttgaa aaccagctga
    14341 tgtcgggtcc atacaaacaa ctggctcgcg cttacatcga gtaccgtcac gatcgcgaca
    14401 ttgaacgtga aaaacgcggt cgcctgaacc aggagatccg tggtctggtc gagcagacca
    14461 acgcctcgtt actcaacgaa aacgccaaca aagacagcaa ggtgattcca acccagcgcg
    14521 acctgctggc cgggatcgtg gctaaacact atgcacgtca gcacctgctg ccgcgtgacg
    14581 tggtgcaggc acatgagcgt ggcgatattc actatcacga tctcgattac tcaccgtttt
    14641 tcccgatgtt caactgcatg ttgatcgacc tgaaaggcat gctgacccag ggctttaaaa
    14701 tggggaacgc cgagattgaa ccgccgaagt cgatctcaac ggcaaccgcg gtaactgcgc
    14761 agattattgc tcaggttgcc agccatattt atggcggcac caccattaac cgtatcgatg
    14821 aagtgctggc accgtttgtc accgccagct acaacaaaca tcgcaagacc gcagaagagt
    14881 ggagcatccc ggacgccgaa ggctacgcta actctcgtac cattaaagag tgctacgatg
    14941 ccttccagtc gctggagtac gaagtaaaca ccctgcacac cgccaacggt cagacgccgt
    15001 ttgtaacctt tggttttggt ctgggcacca gctgggagtc gcgcctgatt caggaatcta
    15061 tcctgcgtaa ccgtatcgca ggccttggta aaaaccgtaa aactgcggtg ttcccgaaac
    15121 tggtgtttgc gattcgcgat ggcctgaacc ataaaaaagg cgatccgaac tacgacatca
    15181 aacagctggc gctggagtgc gcaagcaagc gcatgtatcc ggatatcctg aactacgatc
    15241 aggtagtgaa agtcaccggt tcgtttaaaa ccccgatggg ctgccgcagc ttcctcggcg
    15301 tgtgggaaaa tgaaaacggc gagcagatcc acgatggtcg taacaacctc ggcgtgatca
    15361 gcctgaacct gccgcgtatt gctctggaag caaaaggcga tgaagccacc ttctggaagc
    15421 tgctggatga acgtctggtg ctggcacgta aggcactgat gacccgtatc gctcgtctcg
    15481 aaggcgtgaa agcgcgcgtc gccccgatcc tctatatgga aggtgcttgt ggcgtacgtc
    15541 tgaatgctga cgatgatgtt tctgaaatct tcaaaaacgg tcgtgcgtct atttcgctgg
    15601 gttacatcgg catccacgaa accattaacg cgctgttcgg cggcgagcat gtttacgaca
    15661 acgagcagct tcgcgcgaaa ggtatcgcca ttgttgaacg tctgcgccag gcagtggatc
    15721 agtggaaaga agaaacgggt tatggtttca gtctctacag cacgccgagt gaaaacctgt
    15781 gcgaccgctt ctgccgtctc gatactgctg agtttggcgt ggtgccgggc gtgaccgata
    15841 aaggttacta caccaacagt ttccacctcg atgtggagaa gaaggtgaac ccgtacgaca
    15901 agatcgactt tgaagcgcct tacccgccgc tagcgaacgg tggtttcatt tgctacggcg
    15961 agtatccaaa cattcagcac aacctgaagg cgctggaaga tgtctgggat tacagctatc
    16021 agcatgtacc gtattacggc accaatacac cgattgatga gtgctacgag tgtggcttta
    16081 ccggtgagtt cgagtgcacc agcaaaggct tcacttgccc gaaatgtggt aaccatgacg
    16141 cctcccgtgt gtcggtgact cgccgcgtgt gcggatattt aggtagcccg gatgcacgtc
    16201 catttaacgc cggtaagcag gaagaagtta agcgccgcgt taaacatttg gggaatgggc
    16261 agataggtta atcttcactc tacgttaagc aaatgccgga tgcggcgtaa acgccttatc
    16321 cggcctacat ggcaacaacg attgtaggtc tgataagacg cgacagcgtc gcatcaggcg
    16381 ttgattaccg gatgcatcct atacgcggac tgataagcca ggcgaaacaa tgaattatca
    16441 tcagtactat cctgtcgaca tcgtcaacgg ccccggcact cgctgcaccc tgtttgtctc
    16501 cgggtgtgtt catgaatgcc ccggttgcta taacaaaagc acatggcggg taaattccgg
    16561 tcagacattt actaaagcaa tggaagacca gattattaac gatctgaatg acactcgtat
    16621 caaacgccag ggtatttccc tctccggcgg cgatccgctg catccgcaaa acgtgccgga
    16681 tattctgaaa ctggtaaaac gcatccgcgc cgagtgtccg ggtaaagaca tctgggtgtg
    16741 gacaggctat aaactcgacg aactcaacgc tgcgcaaatg caggttgttg atttgattaa
    16801 cgtactggtc gacggcaaat ttgtgcagga tttaaaagac ccttccctga tctggcgcgg
    16861 cagcagcaat caggtggtgc atcatttgcg atgataagtt ccctgttacc tgagtgcagg
    16921 caacagggaa atgaggaatt aacgatactt ctggtgatag gcgttgcggg tcgttttcag
    16981 ttgctctgca gcagcctgcg cttcttttac tttaccttca tttgccagct tcagcgcgtc
    17041 gtcaatctga ccgaccagaa tgtcgaaacc gtggcggaaa tctttcattt ccgggctgtc
    17101 cggtgattta tcttcgagct tcggcggcgt tgctttttgc gcatccagcg ctgcggcgcg
    17161 catcttcgtt aacgcgtctt tgacttgcgc cgcgttatcc gctttttcga tcacttttaa
    17221 attgtcgttg agggtttcca tattgtcttc aagatcagcg gcaaacgacg cagaactgaa
    17281 taccaacgag gagactgcaa gaatagctaa caggctttta cgcattgctc acttcctttt
    17341 ttatttacac ttcatccttc acactgcctc atcgacggct acgctcattc gcccgggtca
    17401 cgtactgcga gtacgctccc cggccctcat tcactttccg tctcgatgca gtgcgaatga
    17461 ttttgtgtaa ttttttagtt tatagcgcgg caggtcgcgc cagtttttta ctgcccggcg
    17521 attttcatct ccggcaacag cacagaacca cactgtatat tactgcgtgt ttcaatatcg
    17581 ttaccgacgg tgacaatatt gcgccacata tcttttaaat tacctgcgat ggtgatttca
    17641 ctaacgggat actgaatttc gccattctct acccagaagc ccgctgcacc acgggaataa
    17701 tcaccggtaa tggcactcac gccctggccc atcagctccg tcaccaccag cccggtgccc
    17761 atctctttga gcatttgttc gaagcttagc ccttgtccgg caatccgcca gttgtgaata
    17821 ccgcccgcat gtccggtgct tttcagcccc agtttccgcg ccgagtagct ggtcagcagc
    17881 cactgagtca ggatgccatc tttaataata tcgcgacgct cggtgcgcac accttcgctg
    17941 tcgaatggcg tcgacgccag ccctttcagc agatgcggat gctcttcaat ggtcagccag
    18001 tccggcagaa tttgtttacc cagcgaatcc agcagaaagg tagatttacg gtaaaccgag
    18061 ccacccgcta tcgcccccac cagatggcca aaaagcccgg ttgccacttc attggcaaaa
    18121 atgactggcg ctttcatggt ggagagttta cgcggtgaca ggcgcgataa agtacggcga
    18181 gcacagtcgg ccccgaccca ctctggcgtt tgcagatcgc tcatcgcgcg gccaatggtg
    18241 taggcgtaat cacgctccat atcgccattt tcttcggcaa ttacacagct ggagagtgaa
    18301 tgacgcgtag agcagtaacc ctgcaacatg ccgtggctgt tgccaaaaac tttgacaccg
    18361 tagtggctgt taaaactgcc gccttcggta ttggtaatgc gtttgtccgc ctgcaatgcc
    18421 gcctgttctg cgcgggccgc cagttcaatg gcttcatccg gggaaacttc cgcagggtgg
    18481 aacaagtcga gatctggtgc gtcaaaggcc agcagctctt tgtctgccac gccggcacag
    18541 ggatctggcg aggtataacg ggcaatatcc agcgccgcct gtacggtgcg ggcaatggcc
    18601 tgcgggctta aatcggtgga tgatgcgcta cctttgcggt tctggtgata aacagtgatc
    18661 cccagcgcgc catcgctatt gaattcaaca ttctccactt caccataacg cgtgcttacg
    18721 ctaatgccgg tggtcttgct gacggcaact tccgcaccgt ccgatttgcc tgaggccaac
    18781 tccagcgcag tggaaactgc ttcttccaga atcttgcgct gcgcttcaac ttgagagatt
    18841 actttcattg caagtgccat aatgtagaga gtttctctga agtctaacag agaaccgttt
    18901 ttcagtgcgc atcttaactg gtaacattag cctctttttt taaggagcct gagatgacta
    18961 agcagcccga agactggctc gacgacgttc ccggtgatga catcgaagac gaagacgatg
    19021 aaattatctg ggtcagtaaa agtgaaatta aacgtgatgc cgaggagcta aaacgccttg
    19081 gcgcggaaat tgttgatctg gggaaaaacg cgctggataa gatcccgtta gatgcggatc
    19141 tgcgcgcggc tattgagctc gcccagcgta ttaagatgga aggtcgccgc cgccagttgc
    19201 agctcatcgg taagatgctg cgccagcgcg acgtagagcc tattcgtcag gcgctggata
    19261 agctgaaaaa ccgtcacaac cagcaggtgg tgctgttcca taaactggaa aacctgcgcg
    19321 atcgtctgat cgatcaaggt gatgacgcca tcgctgaagt attgaatctg tggcccgatg
    19381 ccgatcgtca gcagctgcgt actctgatcc gtaacgcgaa gaaagagaaa gaagggaata
    19441 agccgccgaa atccgcacgc cagattttcc agtatctgcg cgaactggcg gagaatgaag
    19501 ggtaattttc gttgttgatg tgagtatggt ttgccggatg cggtgcacct gtaggccgga
    19561 taagacgcat caagcgtcgc atcaggcact atgctcaaat gccggatgcg gcgtaaacgc
    19621 cttatccggc aatgctatct caggctgagg ccgaattact gcgcagcttc cgccttcttc
    19681 gccagaccat ccagcagttt ctgatggatc ccaccaaaac cgccgttgct catgaccaga
    19741 atatggtcgc caggctgagc ggttttcacc accatatctg ccagcgtatc cacatcgcca
    19801 ctccagtgtg caggctgaac gcaggcttct gccacttctg ccacctgcca cggaatatgc
    19861 gccggttgca gcaggaagac ttcatcggca cgacctaatg aaggtgccag atcgtctttg
    19921 cagatcccca ttttcatggt attcgagcgc ggctccagca cagcaataat gcgcgccgta
    19981 ccaccaactt tgccacgcag cgccgcaagc gttgccagaa ttgccgtcgg gtgatgggca
    20041 aaatcgtcat ataccgtcac gccattcgct tcaccacgca actccagacg gcgacgagcg
    20101 ttaataaacg aacccagcgc gttagcggca tctgcaggcg ctacaccaac atggcgagcc
    20161 gccgcaatcg ccatcaggcc attgtgcata ttatgttcgc ccaccagcga ccatttcact
    20221 tcgcccactt tttcgccatc cagcaagact tcccattcag aagcgtcagt ggtcagcttt
    20281 ttcgcctgcc agtgaccctg ctcacccacc agctcctgct cgctccagca gcccatcgcc
    20341 atggtctgtt tcaggttgat gtcattttcc ggccagataa tacggccctg ccccggaacg
    20401 atacgcacca gatggtggaa ctgtttctgg atcgctttca ggtcgtcaaa gatatcggcg
    20461 tgatcgaact caaggttgtt gaggatcagc gtacgcgggc agtaatggac aaatttagag
    20521 cgtttgtcga agaaggcgca gtcatactca tccgcttcga taacaaagaa gtcgctttcg
    20581 cccagacgcg ccgaaacctc aaagttcccc ggcacaccgc cgatcacaaa tcccggtttg
    20641 taaccgcact gttccagaat ccaggtcgcc attcccgcgg tggtagtttt gccgtgtgta
    20701 ccggcaacgg ccagcaccca gcggtcgcgc agcacaaaat cgtgcagcca ctgtggacct
    20761 gacatataag ggatgttttt ttccagtacc gcttccacac acggatttcc acgggtcatg
    20821 gcgttgccaa taatcaccag atccggctgc ggatcgagct ggctggcatc gtaaccctga
    20881 atcagctcaa tgccttgctt ctcaagtaag gtgctcatcg gcggatacac attggcgtcc
    20941 gaacccgtta cttcatggcc taactggcgc gccagcatcg ccagaccgcc cataaatgtg
    21001 ccacaaattc ctaaaatatg aatgcgcata cgtcactatc cttttttaat ctgccgctca
    21061 ttttacgcat atgtcgggca agtgagaaac gcatttcagg ataatccgca atttgctggc
    21121 gcgattcacc tgagcgcaac attgagatta tttgttaaga ttgttgcggt cgctttactc
    21181 cataaacatt gcagggaaag ttttatgaaa acgttaggtg aatttattgt cgaaaagcag
    21241 cacgagtttt ctcatgctac cggtgagctc actgctttgc tgtcggcaat aaaactgggc
    21301 gccaagatta tccatcgcga tatcaacaaa gcaggactgg ttgatatcct gggtgccagc
    21361 ggtgctgaga acgtgcaggg cgaggttcag cagaaactcg acttgttcgc taatgaaaaa
    21421 ctgaaagccg cactgaaagc acgcgatatc gttgcgggca ttgcctctga agaagaagat
    21481 gagattgtcg tctttgaagg ctgtgaacac gcaaaatacg tggtgctgat ggaccccctg
    21541 gatggctcgt ccaacatcga tgttaacgtc tctgtcggta ccattttctc catctaccgc
    21601 cgcgttacgc ctgttggcac gccggtaacg gaagaagatt tcctccagcc tggtaacaaa
    21661 caggttgcgg caggttacgt ggtatacggc tcctctacca tgctggttta caccaccgga
    21721 tgcggtgttc acgcctttac ttacgatcct tcgctgggcg ttttctgcct gtgccaggaa
    21781 cggatgcgct tcccggagaa aggcaaaacc tactccatca acgaaggaaa ctacattaag
    21841 tttccgaacg gggtgaagaa gtacattaaa ttctgccagg aagaagataa atccaccaac
    21901 cgcccgtata cctcacgtta tatcggttca ctggtcgcgg atttccaccg taacctgctg
    21961 aaaggcggta tttatctcta cccaagcacc gccagccacc cggacggcaa actgcgtttg
    22021 ctgtatgagt gcaacccgat ggcattcctg gcggaacaag cgggcggtaa agcgagcgat
    22081 ggcaaagagc gtattctgga tatcatcccg gaaactctgc accagcgccg ttcgttcttt
    22141 gtcggcaacg accatatggt tgaagatgtc gaacgcttta tccgtgaatt cccggacgcg
    22201 taatctcctg cgcctctcca cacggagagg cgtttttatc gctgcgcaat attgactctt
    22261 gtcactggcg aactctgacg attctcccac agcaccgtta atccacgctg taaggcaata
    22321 aaaatgaaca gcaaaatgcc gatggcgatt ttcgtccacc aggaactcag cgtaccgtca
    22381 aagttgatat aagtctgaat tagcccctga atcgccacgc caaaaagcgt ccctaatacc
    22441 gttccaacgc caccgctcaa aagcgtaccg ccaattacca ctgaggcgat agcatccagt
    22501 tccacaccta cgcccgccag cgcatatccg gcctgggtat aaatcgagaa gacaatcccc
    22561 gccagcgttg ccagtccggt ggagagcata taaatgcgaa tagtggtgct gcgggtagaa
    22621 atccccatca ggtttgccga cgttgcgttg ccgccaatgg cgtatacctg attaccaaaa
    22681 cgggtacgat gcgcgaggaa tatgccgata accaccaccg ccagcatcag cagtcccatc
    22741 gcacttaagc gaccgccgcc agggattttc cacgcaaggc ttgagagcgt gtcataaatg
    22801 ggatggttta tcgggatcga ctcttctgaa acgagatagc tgacgccgcg caaaaagaac
    22861 attcctgcca gggtaatgat aaatgccggg atcttcaggg cgtcgatcaa aagccccata
    22921 aatgcgccaa aggcacagcc catcaccagc actagcggaa acgccagcag cggcgagagg
    22981 ccgaaatcgc caatcacttt tgccagaaac acgccagtaa aggcgatcac cgaaccgacg
    23041 gagagatcga taccgccaga gaggatcaca aaggtcatgc caacggcgat tatcccaaga
    23101 aaggcgttat cggtcaggat attgcagatc actcttgtgg aagcaaaacc gggaaactgg
    23161 gtcaggcagt agagatagcc cagcacaaag acgccgatgg tgatcatcag cggcaagtta
    23221 cgttttatca tggctacgta ctcctttaat cagactgata aagcgttgcg actgaacaat
    23281 cagcacacaa agcaccacca ccgcttttac gacctggttc atctccggcg gaaagccaga
    23341 aagtaaaatt ccggtgttca tcccctgaat aatcagcgcc cccacgactg agagcagcag
    23401 gttaaagcgc ccgcccatca gcgatccgcc gccaatcacc accgcaagaa tggcgtccag
    23461 ctccagccat aacccggcgt tattggcatc ggcaccgcga atatccgccg ccacgataat
    23521 gcccgcaatc gccgcacaca gcccgctcaa cacgtaggtg agcatgacga tgatccgcgt
    23581 gtttaccccg gcattttttg ccgcccgaat gttgatacca acggcttcga taaacatccc
    23641 cagcgccgtt ttgcgggtca acagccagaa caggagaagc gtcagcaccg cgataatgac
    23701 cggcgttggc aggaacaaca gcgatccgct gccaaaccat gagagatccg gcgagttaaa
    23761 cgtgacgatc tgcccggcgg tgatcagttg cgccacgccg cgcccggcga ccatcaggat
    23821 cagggtggcg acaaacggct gaattttgag gatcgctacc agtatgccgt tccacaatcc
    23881 cgccaggatg ccggtgccca gggcgcttaa caaaacaatc ggcaggctga atcccgcgac
    23941 cgtcatcgca gccgttgtgg ctccggcgat agccatcacc gcccctacgg agagatcaat
    24001 cccaccggtg gcgatcacca gcgtcatacc aatcgccagt aacgcaacgg gagctgcacg
    24061 gttaagaatg tcgatagggc taccgaacaa acgcccatcc tgaagcacca cctgccagaa
    24121 atgcggggct accaggctat cgaccagcag caccagcaat agcgccgcca gctgcggcat
    24181 tcccgttggc cagcgaaagc gccttttcgg cggcgtagtg tccgggagag attgaggcat
    24241 cacactgttc tccttacgcc gcaatggcgt tcatgatcgc cggaacggaa agctctgcca
    24301 gcgggatctc cgccacctgt ttgcgatcgc gcatgataat cacccgatcg gcatagccca
    24361 ccagctcttc cagttcggag gagatcacca acagcgccag accgtcagca cacagcgttt
    24421 caatcaggcg gatgatctcg gcgtgggcac caacatcaat gccgcgggtt ggctcgtcga
    24481 ggatcagaaa ttgcggtcgg gtcagtagcc aacgtgaaag caacactttt tgctgattgc
    24541 cgccagagag aaattcaatc ggttgttcag ttgaaggtgt gcgaatgcca agctggcgga
    24601 taaagcgttc ggcaatctct tgctgctctt tgcgggaaat gggtcgtagc cagccgcgct
    24661 gggcctggag agcgaggatg atattttccc gcaccgaggc ggcagcgatg atgccatcgg
    24721 ttttcctgtc ttccgggcag aatccgatgc ccagtactga agcctgatgt ggcgatcgca
    24781 gggtttgcgg tttgcctttg atcaacgccg tgccgctgtc agcaggtttg ataccgaaga
    24841 tcacttcggc ggtttcggta cgtccggatc ccagcaagcc agccagaccg acgatctcgc
    24901 cggggcgcac ttcgagatca aacggtgcta tcgttccttt tttgccgtaa tttttgaacg
    24961 cggcaacggg tttgtcgctc aacaatgttc gcccggcacg ctgtagcgcg tgggtatcca
    25021 gctcgcgccc cagcatcatt tttaccagtt cgatctgcgg tagctcgcgc gtttcccgac
    25081 agcctacgaa actgccgttg cgtaagacgg tgatccgatc gctgacctga tagacctgat
    25141 cgagaaagtg agtgacaaag atcaggctga cgccgcgatc gcgcaactga cgcatcaggc
    25201 caaataatag ctccacttcc tgggtgtcga ggctggcggt gggttcatcg aggatcagca
    25261 ctttggcgga gagatcgata gcccggcaaa tggcgacgat ttgctgcatc gccaccgaaa
    25321 aacggttaag cggttcgcgc acgtcgaggg agaaaccgta agatgccatc agttcggtgg
    25381 cgcgcttttc catctcttta cggcgtagaa ggccgaaacg tttgggttcg cggcctataa
    25441 atagattatc agcaaccgac atattgggta gcaggttgac ttcctgatag acggtgccga
    25501 taccgagttg ttgtgcatgg gcggtatttt tcggtgagat agcctggcct tccagccaga
    25561 tggtgccgcg atcggcgtgg tatacaccag ttaatgcttt gattagcgtt gattttcccg
    25621 ccccgttttc accaagcagc gccatgattt cgccacggcg caggctgaaa tcaacgttgt
    25681 ctaacgcttt gacgccgggg aaaaatttac ttaatccttc ggtgcggagg atctcctggt
    25741 gttggtcggt cgtcatggtt tcccccggtg taaagcgtgc tcccagtagg catgataaga
    25801 cgcggtaagc gtcgcatcag gcttcagtgc accatcgccg gatgcggcgc gagcgcctta
    25861 tccggcctac gaatcggcat caggcatagc aaccctcaat accccatatt tttcttcttc
    25921 tctaactctt cttttgcggt atcaggcaga taaagggtgg atttggtcag cgtcagcttt
    25981 tcaggcatgg tgccgtcttt tttgtatttc tccagcgcgt cgaaggcggg acctgccata
    26041 ttcggcgtca gttcaacact ggcgttcgct tcgccatcaa tcatcgcttt gtagatatcg
    26101 ggtacaccgt caatggaacc cgtgaggata tctttgcccg gtttcaggcc cgcttcttta
    26161 attgcctgaa ttgcgccaat caccatgtca tcgttatggg cgtaaaccat gcagatgttt
    26221 ttgccgttgt tttccgcttt gataaagctc tccataactt ctttgccttt actgcgggtg
    26281 aagtcacctg actgcgagcg gatgattttg atatttggcg cattcttaat ggcttcggca
    26341 aagcctttct tacggtcaat ggcgacgctg gccccaacgg tgccctgcag ttccaccacg
    26401 ttgcatggtt tgccattcac ttcttttacc agccagtcac caatcaactt gccttcgagg
    26461 atgttgtcgg cagtgacggt ggtcatatag agagatttgt ctttcacatc gatggaacgg
    26521 tcaagcaaga agaccgggat ttcggcatct ttcgcctctt ttaataccgg ttcccaaccc
    26581 gtcgcaacca ctggagcgat aaagatcgca tccacccctt gtgcaacgaa ggaacgtacc
    26641 gctttaatct ggttttcctg cttttgctga ccatcggcaa ttttcaacgt aattccgcgt
    26701 ttttcggcct cacttttcgc cacattggtt tctgcagcgc gccagccgga ttccgatccg
    26761 acctgcgaaa atcctacggt taatggagcg gccaacgcca tagacgacat ggctgccgag
    26821 actgcagaga ctacaagtaa gcgtttccac atagggttgt cctcgtcggg gtaattatta
    26881 ttggtgaaaa gatgttcgcg aaaaaactat agacaattcg ttatgtaacg gattgcgtta
    26941 catcacactt caaaaaagta aataaaacgt taatcacaag tttgtaatcg ctttcatctc
    27001 actatgaaaa atgcggctac ggttatggat tttcctgctc tgtataccgt cttaaaactg
    27061 gcgaaaaagg aaaatgaaga cgaaaacaag caaagacatt cggcgcgagt tggctataat
    27121 actcggcact tgtttgccac atatttttaa aggaaacaga catgagctta ctcaacgtcc
    27181 ctgcgggtaa agatctgccg gaagacatct acgtggttat tgagatcccg gctaacgcag
    27241 atccgatcaa atacgaaatc gacaaagaga gcggcgcact gttcgttgac cgcttcatgt
    27301 ccaccgcgat gttctatccg tgcaactacg gttacatcaa ccacaccctg tctctggacg
    27361 gtgacccggt tgacgtactg gtcccgactc cgtacccgct gcagccgggt tctgtgatcc
    27421 gttgccgtcc ggttggcgtt ctgaaaatga ccgacgaagc cggtgaagat gcgaaactgg
    27481 ttgcggttcc gcacagcaag ctgagcaaag aatacgatca cattaaagac gttaacgatc
    27541 tgccagagct gctgaaagcg cagatcgctc acttcttcga gcactacaaa gacctcgaaa
    27601 aaggcaagtg ggtgaaagtt gaaggttggg aaaacgcaga agccgctaaa gctgaaatcg
    27661 ttgcttcctt cgagcgcgca aagaataaat aagttcttct agcgcaataa ccctgaacgc
    27721 cgagcttcgg ttagtaaggg tttttttatg cccgcgataa ataaacacac cttattccac
    27781 caccgcctgc aagcgtaata acgcctcttc caccacctca tccgcagcca gaccaatacg
    27841 ctttgccagc cgggcgcgta gatccatcat ccgcacctga ttcaccagca ccacgccgtg
    27901 cacatcgcct tcttcgcaat gtaaaggaac gctaaatccg gcataacggg caaaatttcc
    27961 gccctgcgta atgggggcca ccagcgtcat tcccagttga ttaaaggctt gaacggagag
    28021 cacaagcgca ggtcgaccag caccttgctg ttcatggccg cttgctggat caaagccaac
    28081 cagcacaatg tctccccgtt caaattcact tttctttacc atatttcgtc acccgcaggg
    28141 gtggatttac cccagacatc ctgctcgcta agttccgcgg cgttcatgtc acactgtgcc
    28201 agcagttcat caagcgagta gcgcctggag atgggtgtca gaatcagttg attgttgctc
    28261 acttgcgcct ccacgctctg ccccggctgt aagttaagtt ctttcattac gatattggga
    28321 atgaccatac ctgcactgtt cccccatctt tttatggtaa tacgcatctg cacctcctta
    28381 agttatacaa agtataactc acggtgctac aggaaacgtt ttacccctgc gcatttgtga
    28441 acgccagcag agttttttat gcgttaacag atatggaaag cggctcggag agaaaagcaa
    28501 agggtgaggg aattacaaaa cagaatgcga gtcgtctcgc aaaaaacaac gccacccgaa
    28561 ggtggcgtat gcatatggtt acttatccct gtctaaccag tcgccgcttt caattagctt
    28621 taatccatcg acgggtcgtt gataaacgta catccatgca ctcccgtacg gcgtctgaat
    28681 caactggcgc gcgtattcac cgcccctggt gcgcaaggca tcaagttcgg ccagcgtggc
    28741 gttgtcaata cgataaactt caccgtgtac tgttccgttc cccggaactg cgcctggata
    28801 gtggcccagg ctatacaact ggtagttatc gatactgaaa tcgcccagta actgggcatt
    28861 ggtcatccag tgactgttgc cttgtttgtg gcgtaaactg ccgtagacaa atattcgcat
    28921 tgctaaaact cgaactgata gagcaaatcc agtgcctggt ctacaccaga cacggcttcc
    28981 agatatagct taggcatcag gcgataacgt aacgtgagtg ttgctataga gtcaaatata
    29041 cccacgccgt atttcacttg cagacctggc aatacatagc cgctgactac tacctgggag
    29101 gagtcgccta ctccctgggt gtcgagcgct aaattgctta cgccaaacgt ctcgccgatt
    29161 ttacccacaa tctggccact ttgcgcaacc cccagaccaa tcagcatcga ggtcattgcc
    29221 gcactgtcgc tctgatcgct ctccagccct tgtccacgta gcaaataaga caatgcagct
    29281 tgttgcgaca tcgccgggtc agagaagatc tccgctttcg gttcgtccgc cagaccagtg
    29341 acgcgaactc cggcgattac gtcgtcttct gtagcatccg ggttacgaat agcttcaata
    29401 ttaagatacg gttgatccgg cggaccagag aacagtaact cacccttacg cacaatcaga
    29461 tcctgaccat aggcatggaa gcgcccttca gggatgttga tctgcccgtt caggcccagc
    29521 ccttgtttgt cctgaacgac gttaagatcg cccgtcagcc gcgctttcag gccaaaggcg
    29581 tcaatgcgca cattgttgcc aacgtggaca atcaggttac tgttaatcgg aatcgacgcc
    29641 gttttcggct cttccggttg caggttatcg ttaagcatca ccacatcgct ggagacgcct
    29701 actgcgcttt ccggcagatc gtgcaccacg atgcgcgccc acgggacatc cacgcgacca
    29761 tcgagggtaa acaggtttgg tgtagcctcg aatacaacat ctggcgatac atccattcgt
    29821 accatcggcg gcacggtgat ccgcacttta ctgcctttcg ccgttactcg tgcccgccag
    29881 ttttcaattt ggctccagtc ggcatcaccg ttcaggtaga tttcaccctg ctgggtccgt
    29941 actgtaccgg caagcgtcga gcgcataccg ttaaagttga ccgcaagctg gctcggctgc
    30001 atatcaaacg gcataaagtt gccgtcgata tccacacccg taacctgaag ctgaccaaac
    30061 aactgcgggc tttgcacatc accacccaga cgcaagttgg cactcaccat ccccgctgct
    30121 ttttccccac ggttaaagat ggggtttatc atcgcaaggt tgaagttacg gatattgacg
    30181 ttgccaccaa gattacggcg gccttgcgga tcggtcacct gcacctgtcc atcaaactgg
    30241 ccgttattgg tcaggcggat ggtccagccc aattcggcac ggttgttacg caattccgcc
    30301 gtcagattca gtgtctgaaa cgccacgggc agcgccgcat cgttgacggt ttgcgttacc
    30361 tgcacgttac gccccgaaag ggtgatactg ccctgcggca gcccctcttt cgtggtgtcc
    30421 caggcaacat ccgctttacc cgtgaagata ccgctggcct gagtggtttc tggcataaac
    30481 ggtttcagca tggcgaggtc gaagcggttg agattcacca ccgcacgccc ttcggccccc
    30541 gcatcgatag tttgcggcac gcacagttcc gcattcgggt taagccagca gtgtggcccg
    30601 atgctgattt tttgctcctt attgcggtaa tccagcgcaa tatcgcgggt cagcgaccac
    30661 gggccgaccg gcgtctggaa gcgggtattg ctaagagttc ccttccagcg ttcttctttg
    30721 cgatcaaaac ttcctgccag attaagctgc ccggagacag gctcgccctg aatccgcaac
    30781 tgtagctcgt gctgcttttc gctgcctttg gcattcaggg tgacgaggtt gatatttaca
    30841 tccggctgcg aaatttgctc aacgcgtacg tcgagtttcc cggcgatctg atcggtggat
    30901 ttaatgtcgc cttccacgcg aacctgcgcc acggaaagtt cctgccagcg caggccgcgc
    30961 gcggtgatat ctgccagtag ttgtggcgct tccaccgtgc cgcgtacttt caccagccct
    31021 ttcgctgtac cgccaagccc cggcagcgcg ttatccagcc ccggcgcgtt gatggtggca
    31081 tcaagattga gatcttttac ccccagctcg cctttcactt cggcactgtt tggcccgagt
    31141 tccagatgca gccctgggat catccactgc atataactgt tgcctttcag cgtgccgtca
    31201 acgttcactt tgttctgttt gacgttaccg gtcagcttca gttctggcac ctccatctgc
    31261 caggtgccgc cgtacaggct accgcgggtt ttaatcaagc cattgagttt cgacggccac
    31321 tccgggaact ctttggcggt gttaatgcca ttaagcgtta gctcaccgcg ccaactaatg
    31381 gcctgctgcc agtcgagcaa cgccttgagt tcagttttcc cttccagcgc cgcgacggtg
    31441 agtttgtcga gattgacctg ctgttcatta cctttggcat caagggtaat ggtggctggc
    31501 gggatctcct gtcccttcac tgccgtacgc atagagagcg tgtaatcggt cattttgccg
    31561 gtaagtttca gtttcagatc atccgcctga tactgcttct caccagtgaa cggccagtaa
    31621 agctgtttgc tgttcacttc cacgttgagc ggcaatccgg cttccgccag tcgcgtctgg
    31681 gcgcgtaaat ccatatccac cggaccggaa aggttaacgc caatctccag ctgttcgcgc
    31741 agcgcaccgc ccactttcag cttcagtttt tctcctttca acggctccac gttcagtgtg
    31801 ctgttgaggg tgatatccac cggccagttg tctgacagct gcgccgtgcc gctggcgttg
    31861 acgatccctt gactggaatc gatatccagg gcgtccagtt tagtattgcc gtcaatgctg
    31921 ctcactttca gcagcatggt gcgcacggtg atgtccgtgt cgcccgtcac gcgtaactgc
    31981 tcgcctttaa actcttcaat gttcaggtta agcggcaaat gcacgtcggt catttccggc
    32041 aataccgggc gagaaaagag atctttcagc gtttcgccga gcggcttttc ctccggctgc
    32101 ggattttcaa ttttcggttc gaccacttct tcctgcgcca cttccgccac tttcggcaga
    32161 gcaatcagca ggcctttcag cgacgtcggt ttcagggtca gggttttctc ctgccagttc
    32221 aggccggagg tgaagtccat caccgacacc gtggtgtcat caatcttgat gttgacgttg
    32281 tccagcgcca cccgtgtcag ggtgatggga tacggcgtgg agagatccag cggaccgcta
    32341 tcttcctctt cttcaacctg ttcagaagga ggcatttttt tactgtcgat gttgacctga
    32401 atgtctttca gcgccaggtc attaatacaa acgctactgt tccacaggca ctcaagaccg
    32461 accgccagat gcagattacc cgcttttacc gccacgcctg gctgctcata acgaacgtca
    32521 gacaaggtga gatcgcgcca gccgccggtg accttgccaa tatccagtcc tggcacccag
    32581 cgatccgccg ctttaaatac aagatgcagg ccgctggtgg tgcccaccag aaacgccacc
    32641 gatcccagca acagtaagat aacgataacc acgccgaggc tgattttttt ccataaactc
    32701 ataattctgg ccccagaccg atgtaaaact gtaacccgtg ttcgtcttta tccgcgaccg
    32761 gtacggcaaa atcgagtttg attggcccga ccggcgattc ccagcgcacg ccgaccccgg
    32821 taccggtttt aaagtcgctg cggcgaatat cgcttaccgc ttcgccacta tcgacaaaca
    32881 ccgcgcccca ccattttccg gtcacgttgt actggtattc cagcgatccg gttatcaact
    32941 tcgaggcccc tttcaggtca ccgttggcgt atttcggggc gatagatttg tatttgtagc
    33001 cgcgaatact gcgatcgccc ccggcgaaga aacgcagatc cggcggtact ttgtcgaaat
    33061 caccggtttc aatccagccc agcgtgccgc gtgtaacgaa acgatggcga tcgtacagtg
    33121 tgcggatcca gacgttctgc gcctggaaaa cggagaaatc gacatctgaa ccccaggccg
    33181 tgttggagta gtcgatagag tagcgttgcg agtcgcccca ggttggcatc aggccaccac
    33241 gagaacgcgt gcggctaatc atcaccccag gataaaacag catcgtggtg ttggtaattt
    33301 caccctgggt aaagtggtcg aggctccagc gcaggttaat ggcacgctgc cagccgctgg
    33361 agagatccca gtagcgagaa gccaccagcg tagtggagtc agattcggta tcgttcaggt
    33421 cagtgcgctt aaaaccgccc tgcaccaaat aatattgttc cagtggattc ttcagcagcg
    33481 gcattttata gctgaagtcg agggtctgtt ccggcgcgga aatactggta ctggtggtca
    33541 gactgtgacc ataagagttc atccacggct ttttccacgt cgctttcacg cgcggtccca
    33601 cgtccgtaga gtaaccgacc ccggtttcga tggtgttttc agttcgcggc gaaaccacgc
    33661 ccgtcaaggg taatactttc gtttcgcgcg ctttatcaaa ttgtggagcc accaccaccg
    33721 agttaaacca gccggtagca gaaagtcggc ggttcagttc cgccagatct ttcgattcgt
    33781 actcatcgcc ctctttaaac ggcaccagat tttgcaggta ttcatcgcgg atttgtgatc
    33841 cttcaaaggt cacatgccca aagcggtaac gttcgccact gttataatca atatcccaga
    33901 aggctttatg caggccgagc gcaatgccca gctgcgcttt ggtaaattcg ctatcgaaat
    33961 aacctttacg caacgcaatg ctggttaagg actttttgaa attttcataa tcgccctggt
    34021 tcagcaccgt gccaatagcc gggcgagtat cgagcaattt caaatagtct ttatcggtcc
    34081 gcgcgccgcc gcgcaatacc acatcggtgc cgccaattaa caccggcaca cctggcgtga
    34141 ctttggcgat caatacctgc cgccctttct ttggcggtgg acggagatca aattcaatgg
    34201 tcggctggta ataacccagc gctttcagac cttcgcggat ggcatcatcg acgcgtgcgc
    34261 gaaagcgacg gtctggcgtc acttcatcac tttcaatcgt agaaagctgc gcacgaacgt
    34321 tcttttccag ctgtcccgat aacccctcga cctgtagacg gacgttcgcg gcgacggcag
    34381 atccgcttaa gcagagtaag cttacacagc ataactgtcg gatatagcgc acattttctc
    34441 ctgaatatcc ttttttcctg cccctggaac gccgttaaac ggcttaacaa aaatccagta
    34501 atatggatta aaaagcagac taaaccccaa atatttctta tgttttactt tagacctatt
    34561 cacggtggtt attgtgtgca aatacgcctc ttgttacaac cttaacccca atgaccgatt
    34621 ttcgggagag cgacaccatg agtttatttg ataaaaagca tctggtttcc cccgccgatg
    34681 ccctgcctgg acgtaacacc ccgatgcccg tagccacgct gcatgcggtc aacggtcact
    34741 caatgaccaa tgtacctgac ggaatggaga ttgccatttt tgcgatgggt tgtttctggg
    34801 gagtggagcg tctgttctgg cagttacccg gcgtttacag caccgccgca ggctataccg
    34861 gaggctatac gccaaatccg acttatcggg aagtgtgctc cggtgatacg ggtcatgccg
    34921 aagcggtacg cattgtttac gatccttccg tcatcagcta tgagcagttg ctacaggtat
    34981 tttgggagaa tcacgatccc gcccagggaa tgcgtcaggg caatgaccac ggcacgcagt
    35041 atcgttcagc gatttatccg ctgaccccag aacaggatgc cgcagctcgc gccagtctgg
    35101 aacgttttca ggcggcgatg cttgccgccg atgacgatcg tcacatcacc acggaaatcg
    35161 ctaacgccac accgttttat tatgccgaag atgaccacca gcaatatctg cataaaaacc
    35221 cgtatggtta ctgtggaatt ggcggaattg gcgtctgtct gccaccggaa gcatagcgtt
    35281 acgggtacaa atgtagattg ttgataaagt gcgctttatt tatgccagat gcggcgtgaa
    35341 tgccttacca ggcctacaaa atcgtccaaa ttcaatatat tgcagggact gcgtaggcct
    35401 gatcggcata gcgcatcagg cagtattgca tttatcagca gtctgaattt taaccctctg
    35461 gcgactttac agtaccttac gctatactag ccactgaaaa tgccggttca ctttcttcga
    35521 atcggctttc aatgtgtatt tcacacaaat taatcaactt ccccttccga ggatctggcc
    35581 tgaaaggtcg gataagatat gttaaacagt attttagtca tactctgctt gatcgctgta
    35641 agtgcgttct tctcgatgtc tgagatctca cttgccgcct cacgcaaaat caaacttaaa
    35701 ctgctggctg atgaaggcaa tataaatgcc caacgcgttc tgaatatgca ggaaaatccc
    35761 ggcatgttct ttacggtggt ccaaatcggt ctgaacgcag ttgcgattct cggcggtatc
    35821 gtcggtgatg cggcattttc tccagctttt cacagcctgt tctcccgcta tatgtcggca
    35881 gaactctctg agcaactgag ctttattctc tctttctcgt tagtgactgg catgtttatc
    35941 ctgtttgcgg atttaacccc gaaacgcatc ggtatgattg cgccagaagc ggtggctttg
    36001 cgtatcatca acccgatgcg cttctgcctg tacgtttgca ccccgctggt gtggttcttc
    36061 aacggcctgg cgaacatgat cttccgtatt ttcaaactgc caatggtacg taaagatgac
    36121 atcacttctg atgacatcta cgcggtagtg gaagccggtg cgctggcggg cgtgttacgt
    36181 aaacaggaac acgagctgat tgaaaacgtc tttgagctgg aatcccgtac cgttccgtct
    36241 tcaatgacac cgcgtgaaaa cgtgatttgg tttgatctcc acgaagatga gcaaagcctg
    36301 aagaataagg tggcggaaca tccgcactct aagttcctcg tctgtaatga agatattgac
    36361 cacatcatcg gttatgtcga ttctaaagac ctgctgaacc gcgtgctggc taaccaaagc
    36421 ctggcactga acagcggcgt acaaattcgc aacacgctga ttgtgccgga tacgttaacc
    36481 ctttcagagg cgttggaaag ttttaaaacc gcaggtgaag acttcgcggt gatcatgaac
    36541 gagtacgcgc tggtggtggg gatcatcacc ctcaacgacg tgatgaccac gctgatgggc
    36601 gatctggtcg gtcaggggct ggaagagcag attgtcgccc gtgatgagaa ctcatggctg
    36661 attgacggcg gcaccccaat tgacgacgtc atgcgcgtgc tggatattga cgagttcccg
    36721 cagtcgggca actacgaaac catcggaggc tttatgatgt ttatgctgcg taagatcccg
    36781 aaacgcaccg attcggtgaa attcgccggc tacaaatttg aagtggtgga tatcgataac
    36841 taccgcatcg accagctgct ggtgacccgg atcgacagca aggccaccgc cctttcgcca
    36901 aaactgcctg acgctaaaga taaagaagaa agcgtcgcgt aacccccaga aacatcaacg
    36961 gctcctgaat caggagccgt cttattactg catagcactt tggttaagcc atctctgttt
    37021 gcagacgcat aacctgacgg ttaacttcgg acatcactga caaatgcagc ttatccttca
    37081 cttttgggat aagaatctta cccttatcaa attcaaaagc gccaacgtcc ttgatgtata
    37141 accgtccacg gaacaggatc tttacgtact tcgccacctg aagtgggttg taccgttgga
    37201 aaattttcat tgttatctcc tgctgagtat tacgcctgtg cggtgccaca atcggcccaa
    37261 ctattatgag gcgcaaattt taatgcctag tgactataga ctatccgggc aatgtttcca
    37321 ccgcgtataa ctttttttac ctaaaggtta caattattca gaattatctt tttaccgaag
    37381 cgcggtcttc agtataagca ttcatttttc atatgatttg tgcgcttgac cgcaaactgg
    37441 catcacactt gcgggaaatt cgataaatag cacatatgat taaaactcag acccaagtgg
    37501 tcggatcacc tgcatatcat aagaaggaaa caccatgacc ctacgcaaga ttctggcact
    37561 cacctgcctg ctgttgccga tgatggcttc cgcacatcag ttcgaaaccg gtcagcgagt
    37621 gccgccgatt ggcatcaccg atcgtggcga gttggtgctt gataaagatc agtttagcta
    37681 caaaacctgg aacagcgcgc agttagtggg aaaagtgcga gtactgcaac atattgctgg
    37741 tcgcacctct gcaaaagaga aaaacgcgac gctgattgaa gcgattaaat cagcgaagtt
    37801 accgcacgat cgttaccaga ccaccaccat tgttaacacc gacgacgcaa ttccgggttc
    37861 cggcatgttt gtgcgcagca gtctggagag taataaaaag ctttatccct ggtcgcagtt
    37921 tattgttgat agcaatggcg tcgcacgcgg tgcctggcag ctggatgaaa aaagttccgc
    37981 tgtagtggtg ctggataaag acggtcgcgt gcaatgggcc aaagacgggg cgcttactca
    38041 ggaagaggtg cagcaagtga tggacctgct gcataaatta attaataaat agacactctg
    38101 aacccaggat tcaggaacga ctcgcgcgga gtgtaatcca gcggtttacc ctgccagtcg
    38161 tgaacgtgcg ctccggcagc tgcggccaca gcatgtccag cggcggtgtc ccaaatattc
    38221 gttggtccga agcgcgggta cagctgcgcc tgtccttccg ccaccaggca gaatttcagc
    38281 gaagagccga tggacgtggt ctgatgttcg ccaagctgtt gcagatactc tttcagctcc
    38341 gcatctgcat gggaacggct gataaccacc agcggcgggc gcgcatcgcg gacctgaatc
    38401 tgcttgcgca caccgcactc ttctttccag gccttgcctt ctgccgcgct gtacattacg
    38461 ttcattaccg gcgcatacac cacacctaaa atcggtttgc catggtcaat gagcgcaatg
    38521 ttaacggtga attcgccatt gcgtttaata aactctttag taccatccag cgggtctacc
    38581 agccagtaac gctgccagtg ctgacggact tcccaaccgg gaggatcttc ttcagaaagg
    38641 accggaatat ccggtgtcag cgtacgtaaa ccgtccatga taacggtgtg tgcggcaata
    38701 tccgctgccg ttaccggaga attgtccgct ttgctgacga cgtccatcgg tttcgtcccg
    38761 tcgtagacct gcataatggc atcgcctgca ttccgtgcaa gctggcatac ttgatctaac
    38821 atttctccac ctcgtctctg tgagcggtgt taacttattg ttttacttat accctatcgt
    38881 taatgaatgc gccaactgtg atagtgtcat cattttcaaa gcgtaaaatt gtggcattct
    38941 tcactgttct ataagtaaga cgtttattct cccttttctt tcgtattccc gatgataaaa
    39001 ggatgtccct gatgattaag tttagcgcaa cgctcctggc cacgctgatt gccgccagtg
    39061 tgaatgcagc gacggtcgat ctgcgtatca tggaaaccac tgatctgcat agcaacatga
    39121 tggatttcga ttattacaaa gacaccgcca cggaaaaatt cggactggta cgtacggcaa
    39181 gcctgattaa cgatgcccgc aatgaagtga aaaacagcgt actggtcgat aacggcgatt
    39241 tgattcaggg gagtccgctg gcagattaca tgtcggcgaa aggattaaaa gcaggtgata
    39301 ttcacccagt gtataaggca ttaaatacgc tggactatac cgtcggcacg cttggcaacc
    39361 atgagtttaa ctacggtctg gattacctga aaaatgcgct ggcgggagcg aaattccctt
    39421 atgtaaatgc caacgtcatt gacgccagaa ccaaacagcc aatgtttaca ccgtatttaa
    39481 ttaaagacac cgaagtggtc gataaagacg gaaaaaaaca gacgctgaag attggctata
    39541 ttggcgtcgt accgccgcaa atcatgggct gggataaagc taatttatcc gggaaagtga
    39601 cggtgaatga tattaccgaa accgtgcgca aatacgtgcc tgaaatgcgc gagaaaggtg
    39661 ccgatctcgt tgtcgttctg gcgcattccg ggctgtctgc cgatccgtat aaagtgatgg
    39721 cggaaaactc agtttattat ctcagtgaaa ttccgggtgt tgacgccatt atgtttggcc
    39781 atgctcacgc cgttttccca agtaaagatt ttgctgatat cgaaggagct gatatcgcga
    39841 aaggcacgct gaatggtgtt ccggcggtaa tgccaggcat gtggggcgat catcttggtg
    39901 tggtcgactt acaactcagt aatgacagcg gtaaatggca ggtgacgcag gcgaaagcgg
    39961 aagctcggcc gatttacgac atcgccaata aaaaatccct cgcggcggaa gacagcaagc
    40021 tggtagaaac actcaaagcc gatcacgatg ccacacgcca gttcgtcagc aagccaatcg
    40081 gtaaatctgc cgacaatatg tatagctatc tggcgctggt gcaggacgat ccgaccgtgc
    40141 aagtagtgaa caacgcgcaa aaagcgtatg tcgaacatta cattcagggc gatccggatc
    40201 tggcaaaact gccggtgctt tcagctgccg caccgtttaa agttggtggt cgcaaaaatg
    40261 acccggcaag ctatgtggag gtggaaaaag gccagttgac cttccgtaat gccgccgatc
    40321 tttatctcta ccccaatacg ctgattgtag tgaaagccag cggtaaagag gtgaaagagt
    40381 ggctggagtg ctccgccgga cagtttaacc agattgatcc taacagcacg aaaccgcaat
    40441 cactcatcaa ctgggatggt ttccgcacct ataactttga tgtgattgat ggtgtgaatt
    40501 atcagattga tgttacccag cctgcccgtt atgacggcga gtgccagatg attaatgcca
    40561 atgcggaaag gattaagaac ctgaccttta atggcaagcc gattgatccg aacgccatgt
    40621 tcctcgttgc caccaataac tatcgcgctt acggcggcaa atttgccggt acgggcgaca
    40681 gccatatcgc ttttgcttca ccggatgaga accgctcggt gctggcagcg tggattgctg
    40741 atgagtcgaa acgtgcgggg gaaattcacc cggcggcaga taacaactgg cgtttagcac
    40801 cgattgctgg cgataagaaa ctggatatcc gtttcgaaac ttccccgtca gataaagccg
    40861 cagcgtttat taaagagaaa gggcaatatc cgatgaataa agtcgcgacc gatgatatcg
    40921 ggtttgcgat ttatcaggtg gatttgagta agtaaaacac ttctttttcg gcctataaat
    40981 catcaaccgc atccggcatt tattggcgga tgcgatgctg gcgcatctta tccgccctac
    41041 aagccatgca ccgtagacca gataagctca gcgcatccgg cagttatgcc gcacgttcat
    41101 cccgcaccgc caacacctcg ggcaaattca actcaatcca gtccgccagt gcagcaacct
    41161 tttcgctcac ctgctcgccc agcggcgtga ggctgtattc cacatgcggc ggcaccaccg
    41221 gatacgcgat acggttaaga aaaccatcct gttctaacgc ctgtaacgac tgcgcaagca
    41281 tcttttcact caccccaccg attttgcgcc gcaggtcgct aaagcgatga gtaccttcgc
    41341 gtagcgccac cagaatcaat accccccaac ggctggtgac gtgtttcaac acctcgcgcg
    41401 acgggcactg ttccgcaaag agattaccct ctttcagttg ttgcgacagg ctaacctgac
    41461 tcatttcata cttacctttt tgtacgtact tactaaaagt aagtttaggt gttagcgtat
    41521 ttaaacacaa gacaaaacga tggagacttc ccatgatcgc tattactggt gccactggcc
    41581 aacttggtca ctatgttatt gaatccttga tgaaaacggt tcctgccagc caaatagtgg
    41641 ctatcgttcg taatccggca aaagcccagg ccctggcagc acaaggcatt accgtgcgtc
    41701 aggctgacta cggcgatgaa gccgcactga catctgcact tcagggagtg gaaaaactac
    41761 tgctgatctc ttccagcgaa gtgggtcaac gtgccccgca gcatcgtaat gttattaatg
    41821 ccgcaaaggc ggctggcgtg aaatttatcg cttataccag cctgctacat gcagatacct
    41881 ccccgctcgg cctcgccgat gagcacatcg agacggataa aatgctggct gattctggca
    41941 tcgtttacac cctgctgcgc aacggctggt acaccgaaaa ctacctcgcc agcgccccgg
    42001 cagcactgga acacggcgta tttatcggtg cggcgggcga tggcaaaatc gcctcagcaa
    42061 cgcgggcaga ttatgcggca gctgcggcac gcgtgattag cgaagccggt cacgaaggca
    42121 aggtttacga actggcgggc gatagtgcct ggacgttgac acagttagcg gcagagctga
    42181 ccaaacagag cggaaaatcc gttacctatc aaaatctgag cgaagccgat ttcgccgcgg
    42241 cactgaaaag cgtcggactg cccgacggac tggcggatat gctggcggat tctgacgttg
    42301 gcgcatcgaa aggtggtctg tttgataaca gcaaaacgct tagcaaattg attggccgcc
    42361 caacgacaac gttagccgaa agcgtaagcc atctttttaa tgttaataac tagttaatta
    42421 aagtggcatc ctcccgcatc ctctctaata atgacgggat gccgggagca atcatgtctg
    42481 cttcctgaac tttcttctga cagaccaatg gatgccagta atgattagcg gcgtgctgta
    42541 cgccctgtta gcagggttga tgtgggggct tatttttgtc gggccgttga tcgtaccgga
    42601 atacccggcg atgttgcagt cgatggggcg ttatctggcg ttagggttaa ttgcgctgcc
    42661 cattgcctgg ctgggacgcg tgcgtctgcg tcagttggcg cgtcgggact ggcttaccgc
    42721 cttgatgctc actatgatgg gcaacctcat ttattacttc tgccttgcca gtgccattca
    42781 acgtactggc gcgcctgttt ccacgatgat tatcggcacc ctgccggtgg tcattcctgt
    42841 ctttgccaat ctgctttata gccagcgcga cggcaaactc gcgtggggaa aactcgcccc
    42901 ggcactgatt tgtattggca tcggcctggc gagtgtgaat attgctgagt taaaccacgg
    42961 actccccgat tttgactggg cacgttatac ctctggcatc gtgctagcgt tagtttccgt
    43021 ggtctgctgg gcatggtatg ccctgcgcaa cgcccgctgg ctgcgggaaa atcccgacaa
    43081 acatccgatg atgtgggcga cggcgcaggc gctggtcacg ctgccggttt ctctcatcgg
    43141 ctatctcgtc gcctgttact ggctgaatat acaaacgccg gacttctcct taccttttgg
    43201 cccccgtccg ctggtgttta ttagtctgat ggttgcgata gccgtgcttt gctcatgggt
    43261 tggcgcactc tgctggaacg tcgccagcca gcgattaccg acagtgattc tcgggccgct
    43321 gattgttttc gaaacgctgg caggtttgct gtacaccttt ttactccgcc agcaaatgcc
    43381 gccgctaatg acgctgagcg gtatcgcgct gttagtgatt ggcgtggtca ttgcggtcag
    43441 agcaaaacca gaaaaacctt taactgaatc tgtctcagaa agttgacacg ctggcagtga
    43501 gttaaataag cctctgctac gtaagggtta tagcttttgc cttaaagatg catttaaaat
    43561 acatcttata ttattaagaa tgaggtatca gctatggctt atcgcgacca acctttaggt
    43621 gaactggcgc tctctatccc tcgcgcttcg gctctgtttc gtaaatatga tatggattac
    43681 tgctgtggcg gtaagcagac gctggcgcgc gcggcggcac gtaaagaact ggatgttgag
    43741 gtcattgaag ctgaactggc aaagcttgct gaacaaccga ttgagaaaga ctggcgtagc
    43801 gccccgctgg cagaaatcat tgaccatatc atcgtgcgct accacgatcg tcaccgcgag
    43861 cagctgccgg agctgatcct gcaagcgact aaagtcgagc gcgttcacgc cgacaaaccg
    43921 agcgtgccaa aagggctgac aaaatacctg actatgctgc atgaagagct ttccagccac
    43981 atgatgaaag aagagcagat cctcttcccg atgatcaaac aaggcatggg cagccaggca
    44041 atgggaccaa tcagcgtgat ggaaagcgag cacgatgaag cgggcgaact gctggaagtg
    44101 attaaacaca ccaccaataa cgtcacaccg ccgccggaag cctgcaccac ctggaaagcg
    44161 atgtataacg gtattaatga actgattgat gacctgatgg atcacatcag cctggaaaac
    44221 aatgtactgt tcccacgcgc gctggcgggt gagtaatcta aaagctggat ggcattgcgc
    44281 catccagcat gataatgcgg ttatttccgc agttcagcag cccgcttctt accaataaac
    44341 aaccagccca gccccagtgc gataaaccac agcggggtga ccaacagcgc ctggcgagtg
    44401 tcatcttcca gtgtcagcaa cacgaccacg aacacaaaga acgccataca tacccagcac
    44461 atcagcttgc cgagcggcat cttgtagatc gacttctcat gcagatgagg acgctgtttg
    44521 cggtaaacca ggtacgagca aaggataatt gtccagacga acataaacag aatcgcggaa
    44581 acggttgtaa tcatcgtgaa cgcgccaatc acgctaggat tcacatacaa catcaccacg
    44641 ccgccgagca gacagataca cgagaaggtc aaccctttcg cgggtactgc gcgcttagaa
    44701 agtttagcga acgctttcgg tgctacacct tcctgcgcca gaccaaacag catacggctg
    44761 gtagagaaga cgccgctgtt agcggaagac gccgcagagg tcagcaccac aaagttgatc
    44821 acgcttgcgg cagcaggcag ccctaccaac acgaacagtt caacaaacgg gcttttctcc
    44881 gggactaccg aactccacgg cgtcacggac ataattacaa tcagcgcgaa gacgtagaac
    44941 ataatgatac ggatcggaat agagttaatt gcacgcggca gtgatttctc cggatctttg
    45001 gtttccgcag cggttgtacc taccagctca atccctacga aagcgaaaac cgctatctgg
    45061 aatccggcaa agaagccact taaacctttc gggaaccagc cgccatcatt ccacaaatgc
    45121 gcgaatgacg cttccacacc agtcggtgac tgaaagtgca tcgccaccat aaccaggccg
    45181 acgacaatca gcgacacaat ggcgacgatt ttgatcatcg caaaccagaa ctccatctca
    45241 ccgaacattt tcacggtggc gagattgagc gtcagcagca gcactatcac cgccagcgag
    45301 gcgacccagt cggagagatc ggggaaccag aactgagcat aagcagtgat cgccaccacg
    45361 tctgccatac cggttacaac ccagcagaac cagtaagtcc agccggtgaa atatcctgcc
    45421 cacggcccga gtaaatcgga agcgaagtca ctaaaagatt tgtattccag attcgaaagc
    45481 agcaattccc ccattgcccg catcacgaaa aagagcataa aaccgatgat catataaacg
    45541 aaaatgatcg acggcccggc aaggctaatc gttttgccag accccataaa caaccccgta
    45601 ccaatggcac cgccaatggc aataagctga atatgtcggt ttgtgagatt gcgccgtagc
    45661 gactgttcag ccggagcctg atcatcggca acgactttta cctgatctac catgtttttt
    45721 tcttcctgta cctgtctgtg ttgttcaggc tctacggcct ttagtcagtc tatgatacga
    45781 cgaatctgta tcgggactca tcgatattag gtaacaatac gcgggatgaa tactaagatt
    45841 tagatctaat gttaatttta tgtttaaagt gagtgtcata tcacggtgat aacgcgaaac
    45901 agctcacaaa aatacacgct tacggggtct ttgcaacaca aaatagcgcc gtttggcaaa
    45961 ctgaagggtt tattgctgaa tgcctgctcc cctctggttc gaggggaaca gaatgcgctg
    46021 cttagaggat ttccagcagt tcgacttcaa acaccagggt gctgaacgga gggatggatg
    46081 cgcctgcgcc gcgctcgcca tatgccagtt cctgcgggat agtcagttcc catttagaac
    46141 ctaccggcat cagagtcagt gcttcaatcc agccagggat cacgccatta accggaaatt
    46201 cagcgggttc accacgagca acggagctgt caaacacggt gccgtcgatc agtttaccgg
    46261 tgtaatgaac acgaacgcgg tcggtacgtg ccggaattgc gccttcaccc tggttgatca
    46321 cgcggaattg caggccagat tcggtgctat tcacaccttc ttttttggcg ttttcttcca
    46381 ggtatttcac accttcagca gccatcgcct ggaaacgctg acgacgaacg gcatcggcgc
    46441 gctcgtggat ttcacgcagc gcgcgatgca ccacatcaac cggaacagcc ggatgtttgc
    46501 cttccagcgc atcggcaata cctgcaacca gtgcttctgg cagcagccct tccaggccag
    46561 attcactcag ttgttgccct acctgcaaac caatgccgta gcttgcttgc gcttcgatgg
    46621 tgtcaaaagt tggggtggtc atcgtatttc ctttcttagg gtataaaagt agcgggcagc
    46681 atatcagcca cacttctttg ggtaaaactt tgtcgcagga atgatgacaa atcccgggga
    46741 aaaagaaaca atagcaatat cccgtatgaa tataataaag gcgggtttac cacggacatc
    46801 atagcgttag cttattcata ggctatgatt gaggaacaag acgcggagca ggaggaaacc
    46861 atgcccgggc gctttgaact aaaaccaacc ctggagaaag tctggcacgc gccggacaat
    46921 tttcgcttca tggacccgct gccgccgatg catcgtcggg ggatcattat tgccgccatt
    46981 atattggtgg tcggatttct gcttccatct gatgatacgc ccaacgcgcc ggtggtgacg
    47041 cgtgaagcgc agttagatat tcagtcgcaa tcacaaccgc cgacagaaga acagctgcgg
    47101 gcgcaattag tcacaccaca aaatgatcct gatcaggtgg ctccggtcgc tccagaacct
    47161 atacaggaaa gccagccaga agaacagccg caaactaccc aaacacaacc attccagcca
    47221 gatagcggaa ttgataatca atggcgctct taccgtgtcg aacccggtaa aacgatggcg
    47281 cagctgttcc gcgaccacgg actgcccgct accgatgtct atgcaatggc gcaggtagaa
    47341 ggcgcgggta agccgctgag taatttgcaa aacgggcaaa tggtgaaaat ccgccagaac
    47401 gccagcggcg tggtgacggg cttaaccatt gatacgggga ataatcaaca ggtcctgttc
    47461 acccgccagc cggatggcag ttttattcgt gcgcggtaga tgaagggtca accaaaagcc
    47521 agctaaggat tgtctctttg atgaccttac gtctggcttc cagtgcctgg ggggaaacca
    47581 tactgatatg ataaaccagg ccaagcgtat gctggttgat caaataatat ccgccaagcg
    47641 cagcaatatt aatattcacc tgcaatgggt cgatatctgg cttaaaaata ttttgtttct
    47701 tcccttcatc caataaggat tccattaact gcaagtgcgc atggttaatt tctaaaagac
    47761 gctgtgattt tgcataatgc acacccttac tttgattttc actatgcaca atttttaaaa
    47821 accagggatt agaaatataa taatcccatg taaaatcgat tattttctca atggctttct
    47881 gtggcggaag atctgagaaa tcaagggcct ttt
//
LOCUS       DAFGPF010000024        47471 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFGPF010000024 DAFGPF010000000
VERSION     DAFGPF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47471
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.024"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            137..379
                     /locus_tag="LSX49_001598"
     CDS             137..379
                     /locus_tag="LSX49_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168025.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            494..1132
                     /locus_tag="LSX49_001599"
     CDS             494..1132
                     /locus_tag="LSX49_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HBL7168026.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGATWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            1129..1866
                     /locus_tag="LSX49_001600"
     CDS             1129..1866
                     /locus_tag="LSX49_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HBL7168027.1"
                     /translation="MIKQTIVALILSVGASSVFAAGTVKVFSNGSSDAKTLTGAEHLI
                     DLVGQPRLANSWWPGAVISEELATAAALRQQQALMTRMAELAADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQS
                     FTPGRDVASYLSDQSLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETPDALNADILQTLTQRIPQ"
     gene            1866..3962
                     /locus_tag="LSX49_001601"
                     /pseudo
     CDS             1866..3962
                     /locus_tag="LSX49_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
     gene            complement(4009..4287)
                     /locus_tag="LSX49_001602"
     CDS             complement(4009..4287)
                     /locus_tag="LSX49_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168028.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            4502..4912
                     /gene="psiE"
                     /locus_tag="LSX49_001603"
     CDS             4502..4912
                     /gene="psiE"
                     /locus_tag="LSX49_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HBL7168029.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            complement(5006..5896)
                     /gene="malG"
                     /locus_tag="LSX49_001604"
     CDS             complement(5006..5896)
                     /gene="malG"
                     /locus_tag="LSX49_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HBL7168030.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            complement(5911..7455)
                     /gene="malF"
                     /locus_tag="LSX49_001605"
     CDS             complement(5911..7455)
                     /gene="malF"
                     /locus_tag="LSX49_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HBL7168031.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKIYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGT
                     LTNNQSGVKYRPNDQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            complement(7609..8799)
                     /gene="malE"
                     /locus_tag="LSX49_001606"
     CDS             complement(7609..8799)
                     /gene="malE"
                     /locus_tag="LSX49_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HBL7168032.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFETDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYQ
                     DELAKDPRIAATMDNAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALKDAQT
                     RITK"
     gene            9164..10279
                     /gene="malK"
                     /locus_tag="LSX49_001607"
     CDS             9164..10279
                     /gene="malK"
                     /locus_tag="LSX49_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HBL7168033.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            10351..11691
                     /gene="lamB"
                     /locus_tag="LSX49_001608"
     CDS             10351..11691
                     /gene="lamB"
                     /locus_tag="LSX49_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HBL7168034.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYTGSSSTNPYYGKAVSADFNGGSFGRGDSDEWTFGAQMEIWW"
     gene            11924..12844
                     /gene="malM"
                     /locus_tag="LSX49_001609"
     CDS             11924..12844
                     /gene="malM"
                     /locus_tag="LSX49_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HBL7168035.1"
                     /translation="MKMNKSLIALCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLSTGGQQLNVSGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSVPDIPDPIARHTTDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAAPAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            13023..13520
                     /gene="ubiC"
                     /locus_tag="LSX49_001610"
     CDS             13023..13520
                     /gene="ubiC"
                     /locus_tag="LSX49_001610"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HBL7168036.1"
                     /translation="MSHPALTQLRALRYFTEIPALEPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            13533..14405
                     /gene="ubiA"
                     /locus_tag="LSX49_001611"
     CDS             13533..14405
                     /gene="ubiA"
                     /locus_tag="LSX49_001611"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HBL7168037.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARTLFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(14560..16983)
                     /gene="plsB"
                     /locus_tag="LSX49_001612"
     CDS             complement(14560..16983)
                     /gene="plsB"
                     /locus_tag="LSX49_001612"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HBL7168038.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTKQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            17154..17522
                     /gene="dgkA"
                     /locus_tag="LSX49_001613"
     CDS             17154..17522
                     /gene="dgkA"
                     /locus_tag="LSX49_001613"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL7168039.1"
                     /translation="MANNTTGFIRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            17632..18240
                     /gene="lexA"
                     /locus_tag="LSX49_001614"
     CDS             17632..18240
                     /gene="lexA"
                     /locus_tag="LSX49_001614"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HBL7168040.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            18313..19638
                     /gene="dinF"
                     /locus_tag="LSX49_001615"
     CDS             18313..19638
                     /gene="dinF"
                     /locus_tag="LSX49_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HBL7168041.1"
                     /translation="MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVY
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
                     IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGI
                     SGEMLKTAWRGNFRHLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGE
                     HIIALLTSLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAA
                     GFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNDTWFVAT"
     gene            19754..19963
                     /locus_tag="LSX49_001616"
     CDS             19754..19963
                     /locus_tag="LSX49_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL7168042.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVDSWEKRHDYRW"
     gene            complement(20005..20520)
                     /gene="zur"
                     /locus_tag="LSX49_001617"
     CDS             complement(20005..20520)
                     /gene="zur"
                     /locus_tag="LSX49_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HBL7168043.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALEFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCSACVEVEACRHPEQCHH
                     DHSIQVKKKPR"
     gene            20676..21671
                     /gene="dusA"
                     /locus_tag="LSX49_001618"
     CDS             20676..21671
                     /gene="dusA"
                     /locus_tag="LSX49_001618"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HBL7168044.1"
                     /translation="MPAESHTVYPAYRFSIAPMLDWTDRHCRYFLRLLSRNTLLYTEM
                     VTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEARGYDEINLNVGCPS
                     DRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYEFLCDFINTV
                     SGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKSL
                     EEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPVAVVRAMYPYIEREL
                     SQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVLEHALKLVADKR"
     gene            21805..22047
                     /gene="pspG"
                     /locus_tag="LSX49_001619"
     CDS             21805..22047
                     /gene="pspG"
                     /locus_tag="LSX49_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HBL7168045.1"
                     /translation="MLELLFVIGFFVMLMVTGVSLLGIIAALIVATAFMFLGGMLALM
                     IKLLPWLLLAVAVVWVIRAIKAPKVPKYQHYDRWRY"
     gene            complement(22212..23195)
                     /locus_tag="LSX49_001620"
     CDS             complement(22212..23195)
                     /locus_tag="LSX49_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HBL7168046.1"
                     /translation="MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVKNKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSMHNIN
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREENLVERLKEITGGKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDARRAHEILESRATQGSSLLIP"
     gene            complement(23301..25337)
                     /locus_tag="LSX49_001621"
     CDS             complement(23301..25337)
                     /locus_tag="LSX49_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBL7168047.1"
                     /translation="MIDETLTALTDIKMPHYAPLAQASGSIDLNGTILPEYCCNTLVL
                     GSGAAGWRAAVELKRQNVDVMVASSKAFWGTSACSGSDKQTLHTANTRANGDHFLTLS
                     NTLAAGGAMDHDTAYVEAVGSVNTCEVLKYLGLDLPEDLFGATLRYQTDHDEFGRATS
                     CGPRTSRLMVKVLAQEAMRLNIPLCDHTTAIHILTSGEGENRRVVGVIAIDKACRDNP
                     WRMVVIRCQHLVLATGGPGELYRDSVYPVNCFSALGMALEAGITLVNLTESQFGIGTP
                     RSQFPWNLSGTYMQAMPRIYSQDHSGRQYNFLAAYYPTTRMLASAIFRKGYQWPFHAE
                     RMLEYGSSLLDVAVYEETQKGRDVFLDFLREPEPAADGTSFNLQELDDDVIDYLQQNH
                     ALLAQPLARLTQMNPLAIRLYQMHGHDLTASPLKFTLNNQHLNGGIEVDIWGRTSLTG
                     CYAAGENAGTHGVTRPGGAALNAGQVFARRCALHIAHQKSQDRPLERQQILSTINEAQ
                     QYLNQGLLRDDVRETIQNTMSHHAAILCHTQGINTAAQTLATLCEDIRREGIQCDENS
                     LAQSFQWRQSAQLALAVLRSLQCYVENGGGSRGARAIYDGEAGIAPQTPGGPLLAWRF
                     RPENQDARQYMICVCREANDYQTWTRPCRERGVLTLTNFERQWQNWIAATPFQY"
     gene            complement(25348..26628)
                     /locus_tag="LSX49_001622"
     CDS             complement(25348..26628)
                     /locus_tag="LSX49_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001057569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL7168048.1"
                     /translation="MNMTTSVPQTPSLFRRIMTKLAAFAPGIFLIGYSIGTGSITTMA
                     KAGANYGVSLMWAVALSCIVTWFLIRIYGRYASVTGERALTAFRRHIHPGVAMLFLIG
                     LTVAVSGSIMGVMGILADVMATWSTTWFSGGISALAWAIAMVIMINVMLWTNSNAGFD
                     KILSALVGIMGLAFVINFFIMMPPVADLLAGFIPSVPDPVAGDNSTPFLIISGMVGTT
                     VAPAMFLMRTTLVKSNGWGVDNLPHQNRDAIVSAGMMFIISAAVMAAAAGTLYQTGTG
                     LNNASQMVIILEPIAGSAAVGLFVIGIVAAGLSSQFPNLLLTPWLLADWRDTSNEVSP
                     GYRILMTVMSLLCLVVPLFHARPVLVMIASQAFNAIILPLTVLCMFWLANKPSLMGKY
                     RCSRWENVMFIAISVFTLIMGYMAMSGLIESLMK"
     gene            complement(26655..27434)
                     /locus_tag="LSX49_001623"
     CDS             complement(26655..27434)
                     /locus_tag="LSX49_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBL7168049.1"
                     /translation="MNNGTIDLQRNGFIATLVINRPAKLNALTPEMLEQLLAHCHTLE
                     TDSEIRVVLLTSASEKAFCVGADIHRWTSLSALDMWRNWIRRGHQAFDALAQLPQPVI
                     ALLHGLAYGGGLELAATADIRICSAEAQMALPETGLATVPGWSGTQRLTALLGRSLVK
                     ELVFTGEPLDAQRALSCGLVNRVVAREALHDAGLQLAQRIAQRAPVAVQIAKQVIDAG
                     EGIAVASTLEALAGAFSATTEDAHEGSQAFTEKRQPHFQAR"
     gene            complement(27427..28998)
                     /locus_tag="LSX49_001624"
     CDS             complement(27427..28998)
                     /locus_tag="LSX49_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HBL7168050.1"
                     /translation="MCSVRTITAPEAADLIVDGAVVTVSSSSGMGCPDAVLAAIGERF
                     QRAGHPQNITSIHPIAAGDMYGVKGIDHLAQPGLLAKVIAGSYPSGPSSMTPPLIWQM
                     INDNAIPAWNLPSGILFDMHREAAAHRPGVLTQTGMDTYVDPLLQGGAMNEKAAQQSL
                     VERVRFANDDWLFFPSIVPQVAIIRATTADERGNLTYEHEGAYLGPLEQATAVRNNGG
                     IIIAQVKRQVAAGSLKPKEVRIPGVLVDYIVIAPEQTQTTQTQYEPAISGEISRPLSA
                     FRYMEHGPARVIAQRVAQELQSGDAVNIGFGISANVPRILLEQGRHGDVTWLLEQGAI
                     GGVPLLEFQFGCASNAEAFLPSPQQFTYFQGGGFDLTLMSFLQIGADGSVNVSHLPAR
                     PHVTAGCGGFIDITSHAKRIIFSGFFNAGAQLQLEEGQLRIIKEGKAKKLVQDVAHVT
                     FSGKRAIRLGQQVQYITERCVLELTPDGLLVTEIAPGIDPERDILAQSDAPLRLADDL
                     KLMNPLYFQQGSHHE"
     gene            29254..30288
                     /locus_tag="LSX49_001625"
     CDS             29254..30288
                     /locus_tag="LSX49_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL7168051.1"
                     /translation="MAKSDTGRKRVTLTDVARAAGVSKSTVSLVLNDSSLIKKETQQK
                     VQQAIEQLGYVYNRFAANLRSQKSLTIGVVIDDLINPFFAEFTMGLEMTLAEHGFITV
                     MSNTSQRSDRQKQVLDTLLEHHVAGIVLCPVNSTSEADLQRYANSSTPLLITMRPLDW
                     QQLPVDYVGVDSHAGVREATEYLIQQGHRDIVFIGGLTHHMRYQGYLEAMNHHGLQPW
                     STDAFSLRAEPTQANGYQLMQQLLDMPSPPTAVICYNDLMAFGAESALGERGLFAGED
                     ISLIGNDGVAACAYSNPPLTTIAVEPLALGKQAAQQILRRIAQPDAPLSHYIYRPTLQ
                     IRASTGKRGR"
     gene            30361..31776
                     /gene="dnaB"
                     /locus_tag="LSX49_001626"
     CDS             30361..31776
                     /gene="dnaB"
                     /locus_tag="LSX49_001626"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBL7168052.1"
                     /translation="MAGNRPFNKQQTDNRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            31829..32908
                     /gene="alr"
                     /locus_tag="LSX49_001627"
     CDS             31829..32908
                     /gene="alr"
                     /locus_tag="LSX49_001627"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBL7168053.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEANLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGAPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            32931..33488
                     /locus_tag="LSX49_001628"
     CDS             32931..33488
                     /locus_tag="LSX49_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBL7168054.1"
                     /translation="MSYSEIAACLAYAVSVWLAARNNVHTWWIGIIGSILYGWVFWSV
                     QLYADVTLQLFFIVTSITGWIHWLKGQGGDILPVRRTQASHFFLLLLCAVVVAGGYGF
                     LLHTFTNAWAPWLDSLILTFSVLAQFMLMGRRIENWYVWLAVNTLAVPLYMTRGLNLT
                     AGLYFLFWINAWYGLYQWRKELQTS"
     gene            33485..34489
                     /locus_tag="LSX49_001629"
     CDS             33485..34489
                     /locus_tag="LSX49_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7168055.1"
                     /translation="MKPFATGLVVGKFAPLHCGHEKLINTALAQCEELFIISYSVPEM
                     PDCEPEKRLTWLQVRFPQATFLVLTPELVARYNLPAIPHNNADADIHRHYVATLCLQI
                     LRCRPHAVFTAEDYGDGFANVLARRFAQPVEHVRMARPVGDEAPSGTLIRSDVHRYRY
                     MLANDVYYSFVRRICLLGGESTGKSTLSKALAGVLDTVYVAEFGRDYWEEKNGILTAD
                     DLLHIACEQVRREQQAEANHYLICDTSPLTTLFYALDQYGHAPQELHQLAEREYSLVV
                     LCGAEFPFVQDGTRQGEVFRARQQVWYEQELSRRNIPYLSVSGPLQERVEQILRQLPD
                     "
     gene            34571..35764
                     /gene="tyrB"
                     /locus_tag="LSX49_001630"
     CDS             34571..35764
                     /gene="tyrB"
                     /locus_tag="LSX49_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HBL7168056.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLKAVADAEARLNAQPHGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTL
                     GGSGALKVGADFLKRYFPESSVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNEQWDAVIEILKARELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLVEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDQLREEFGVYLIASGRMCVAGLNTQNVHRVAKA
                     FAAVM"
     gene            35946..38690
                     /locus_tag="LSX49_001631"
     CDS             35946..38690
                     /locus_tag="LSX49_001631"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001468317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HBL7168057.1"
                     /translation="MENMTSPGTLLSGDNATWLEEYYQTWLRTPEQLPEDWRRFFLSP
                     ELTVQSVSGDNNISGATLKKQAAVIQLINAWRTQGHLRAKLDPLGLNPPADVPSLQPG
                     FWGLSEEDLLQEFSVTFGAHTTQMPLKQLLNLLEQAWASSQAYELAHLENREEINWLL
                     SRIESSNAPQADAQTCIARFEKLMAAETLERYLHTRYVGQKRFSLEGGESAIPALDTL
                     TKRLRAQGVEEMVIGMAHRGRLNVLVNLLNKDPAQLFAEFEGKQTIGSGSGDVKYHMG
                     YSSNLETPAGSLHVALAYNPSHLEIVNPVVLGQVRARQERRGEDGQAKVVGVLIHGDS
                     ALGGLGVNQTTFNLSQTQGYGTGGTLHLVINNQIGFTTSRLQDMRSSRYCTDIAKMVA
                     APIIHVNGDDVDAVCQVMELACEWRDTFRRDIIIDICCFRKHGHNESDEPRLTQPQMY
                     QAVDAHPGTLARYGESLARRGLLTQAQQDEMTARYRDWLDSCQKREPQPLKPAIHSFS
                     ANWYGLTNPHWSAPVSTALPRQKLAAYGEIISTLPPDVVAHPTIKRQLALRQDMAAGT
                     QPVDWGMAEMLAYASLVDAGVGVRLSGEDSGRGTFSHRHAVVHHQTEARRYLPLQHIR
                     AGQASFDVYDSVLNEEALLAFEYGYSTSAPQQLVIWEAQFGDFANGAQVAIDQFISSG
                     ETKWDRYSGLTILLPHGYDGQGPEHSSARPERWLQLCAENNMQVVMPSESAQMFHLLR
                     GQALRPMRKPLVIMMSKRLLRFKGAMSELCEFTDDAYKPVITDPQLHQSQKVKRVILC
                     SGQVYYDVLEARKQREHEDEVAIVRLEQLYPFPVAELNDVLASWPNCCEWIWLQEEPE
                     NQGAWRQIRHELAALKINTPYWQYAGRPAAAAPATGYGRVHKQQIDEFLAAAFADIQP
                     "
     gene            38723..39877
                     /gene="odhB"
                     /locus_tag="LSX49_001632"
     CDS             38723..39877
                     /gene="odhB"
                     /locus_tag="LSX49_001632"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001468318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HBL7168058.1"
                     /translation="MIEITVPVLPESVTEGTLTTWCKQEGEHVKRDDVIAELETDKVI
                     LEIPAPHDGVLSNIIVSEGSTVTSAQLLAHLKPQAVIEETVTPVTETLAMPSARLEAQ
                     RSGVELADVAGSGRNGRILKEDVQRVTPAPAIQPERVAEIAPAKPLTPGARQERREPM
                     SRLRQRIAERLLASQQNNAILTTFNEVNMQSVMDLRARWKDRFAEKHGVKLGFMSFFV
                     KAVTRALERFPVVNASVDGNEIIWRDYCDIGIAVSSNRGLVVPVLRNAQSLSLVEIER
                     QIAEYATQARNGKLPLEALQGGTFSITNGGTFGSMMSTPIINPPQSAILGMHAITPRP
                     VAENGQVVIRPMMYLALSYDHRIIDGQEAVHTLVAIRELLESPEQLLLDL"
     gene            39889..41307
                     /gene="lpdA"
                     /locus_tag="LSX49_001633"
     CDS             39889..41307
                     /gene="lpdA"
                     /locus_tag="LSX49_001633"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000103914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL7168059.1"
                     /translation="MSTIFDVAVMGGGPGGYVAALRAAQNGLSVVCIDDGVNAQGEPS
                     PGGTCLNVGCIPSKSLLQSSELYAQVQHEASIHGVNVDGVSFNAAAMIQRKDAIVSRL
                     TMGISLLFKKNKVKHLCGLATLECAQDEIWQLRVNDQHLHARNVVIATGSQPRQLPGV
                     TIDNQQILDNRGALALSEVPPRLGVIGAGVIGLELGSVWNRVGSDVTLLEMAPTFLPA
                     LEARLSNEVRKAMIASGMKMQLAVEIEAIEQRDDGVHVRWRQGEKREESRFDKLILAI
                     GRVPRLSGVDLVQLGLEADNRGGIAVDNLCRTGKAGLWAIGDVVRGPMLAHKAMAEGV
                     VVADQIAGLVVEPINFALIPSVIYTQPEVAWVGENEASLKAAGRVFNKGNSLFAGNGR
                     ALALGQEGGRCTLYSDKHTDRVLGGAIVGPQASELINEIALAMTFSASGEDIACAIHA
                     HPTLSEVIHEAAMALNNKALHG"
     gene            41329..42498
                     /gene="sucC"
                     /locus_tag="LSX49_001634"
     CDS             41329..42498
                     /gene="sucC"
                     /locus_tag="LSX49_001634"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HBL7168060.1"
                     /translation="MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKG
                     AVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLGSQLVTYQTGPEGQYVSSILLCE
                     NIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
                     CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAK
                     VSLDDNALYRHPELQVLRDETQEDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATM
                     DIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVNIFGGIVRCDMIARA
                     IIHALNEASITLPVVVRLSGNNAAEGQRLLAESGLTVEAVDSLDDAAKRIIALLN"
     gene            42511..43383
                     /gene="sucD"
                     /locus_tag="LSX49_001635"
     CDS             42511..43383
                     /gene="sucD"
                     /locus_tag="LSX49_001635"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HBL7168061.1"
                     /translation="MSVLINKHTRVLVQGITGKNGTFHTEQAIAYGTQIVGGVTPGKG
                     GQRHLDRPVFDSMKDAMRQTEADASVIYVPAPFVLDSVVEAIEAGVKLVVVITEGVPT
                     LDMVKVRRLLDCHPDVRLIGPNCPGVITPGECKIGIMPGEIHRPGRIGIVSRSGTLTY
                     EAVAQTTALGLGQSTCIGIGGDPVPGTNFIDALRLFENDPQTDAVIMIGEIGGNAEER
                     AAEFIRHDMNKPVVGYIAGVTAPKGKRMGHAGAIISGGSGSAEDKFRAFDKAGMAWTR
                     NPALLGETLWNVIK"
     gene            43595..45094
                     /locus_tag="LSX49_001636"
     CDS             43595..45094
                     /locus_tag="LSX49_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HBL7168062.1"
                     /translation="MSSISHGAPQKRRIIPNPGLWLAIIAGIIITLLPLGDTLPVAGQ
                     NMIAILVFAIIVWISEAMDYTASAIVISALIIFMVGFAPDMNHPDTILGTAKALKMTL
                     SGFSNSALALVAAAMFIAAAMTITGLDKRIALFTMSKIGASSRSIIIGAIVVTIVLSL
                     VVPSATARTACVVPIMMGVIAAFKVDKHSRLAASMMIVIAQATSIWNVGIQTSSAQNL
                     LSIGFINKTFGAGHSVSWLDWLLAGAPWSLTMSVILYFLARKLLPPETEAVEGGSEAI
                     KKALAELGPTTGKEKRLIGISLLLLLFWSTGGKLHSIDTTSVTLAGLAIMLLPGIGVM
                     SWKEVEKRVQWGTLLMFGIGISLGSTLLDTQAASWMANYVVKGFGLDGLPSLAIFAIL
                     AAFLIIIHLGFASATALTAALLPILISLLSSLPPELGVNPVGMTILLAFSVSFGFILP
                     INAPQNMVCMGTDTFTPRQFTRVGLYLTVIGYLLLLLFAATWWKILGLM"
     gene            45106..46179
                     /locus_tag="LSX49_001637"
     CDS             45106..46179
                     /locus_tag="LSX49_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ldh family oxidoreductase"
                     /protein_id="HBL7168063.1"
                     /translation="MSLQIAVEKVRWLAAGLLELNGCDADIAQDVAEHMIEAERYGFA
                     SHGVTLLPKYLENIARGDVTANARPECLTSEGNLQRFHAHNGFGQHAGKVAVNAAIEQ
                     TKHRGFCLLTLCHAHHLGRMGHYGQMVADQGLAMLAMSNVTGRPALVAPWGGAEPRMT
                     TNPFCFAWPFSDGRPPILVDFATSSMALNKARVMSSTGKQAAPGQLIDAQGNPSNDPG
                     VLFSNPPGALLPFGEHKGFGLALMIEMMAGILSGGDTIAEDHQTDGSAHNHLFALIID
                     PDQFTDLAGEKGQFFADYLLATQPQPGGNPVIYPGMPEAANRERNAKMITIPVSFWSW
                     VVEHYARKGIDLGLHPQESALAG"
     gene            complement(46168..>47471)
                     /locus_tag="LSX49_001638"
     CDS             complement(46168..>47471)
                     /locus_tag="LSX49_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBL7168064.1"
                     /translation="RFACEQTLTLAGYRVISCCDAEHSIPLIQSQANIIILTDVRLPG
                     ISGLELLSYINEMDSKIPVILITGHGDVEMAVDAMRNGAFDFIEKPSSSDKLLSIIAR
                     AVEKRRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKMILNVADTGADVLIYGETGC
                     GKEVVARMLHHWSTRRQGQFVALNCAGLPETLFESEIFGHEAGAFTGAVKKRIGKIEH
                     ANGGTLFLDEIEGMPSGMQVKLLRVLQERTIERLGANQLIPVNCRVIAATKEDLLRRS
                     EEHLFRLDLYYRLNVVSLNIPPLRQRREDIPELFYWFASQAAQKYNRPLPDISPMLLA
                     WLQSQSWPGNVRELKHNAERFVLGLLTHHQPVPMTQQEESGLTACIDAFEKKLIEDML
                     RQTEGQVSLTARLLQLPRKTLYDKLNKHQIQPQVYRPESSS"
BASE COUNT        11278 a        11889 c        12753 g        11551 t
ORIGIN      
        1 tgatattcat tccaattgtc ctaaaactcc atcactaatt ccccgcgccg taattcgcat
       61 gctttagttg tgtatactcg atcccgcccg aaatgttttg ggtaaatctc cattcattca
      121 atgaagggaa attgttatga aaaaagttct gtatggcatt tttgccatat ctgcgcttgc
      181 ggcgacttct gcgtgggctg cacctgtaca ggtgggcgaa gcggcaggat cggcagcaac
      241 gtcggtttcg gcgggtagtt cctccgcgac cagcgtcagc accgtaagct cggcggtggg
      301 tgtcgcgctc gcggcaaccg gtggcggtga tggttctaat accgggacca ccacaaccac
      361 gaccaccagt acccagtaat aaagtatgta tccccaaaat aattcgagtc atcgcatctg
      421 aagcttgaag tatgaagggg attaaccata accacactcc ggtgtggtta ttctgcccct
      481 ctggagaaga gtcgtgaagc gaccagcact cattcttatc tgcctgctat tacaggcctg
      541 ttcagccacg actaaagagc tgggcaattc actgtgggac agtctgttcg gtacgccagg
      601 cgtacagctg acggacgatg atattcaaaa tatgccctac gccagccagt acatgcagct
      661 taatggcggg ccgcagttat ttgtggtgct ggccttcgct gaagacggac aacaaaaatg
      721 ggtcactcag gatcaggcca cccttgtcac acaacatggt cgtctggtga agactttgct
      781 tggcggcgac aacctgattg aagtgaataa ccttgccgcc gacccgctga ttaaacccgc
      841 acaaattgtt gatggtgcaa cctggacgcg cacgatgggc tggaccgagt accagcaggt
      901 acgctacgcc accgcacgct cagtcttcaa atgggatggc accgataccg tcaaagtcgg
      961 cagcgatgaa accccggttc gcgtgctgga cgaagaagtc tccaccgacc aggcgcgctg
     1021 gcataaccgc tactggatcg acagcgaagg gcaaattcgc cagtcggaac agtatctcgg
     1081 cgcggattac ttcccggtga aaaccaccct catcaaggcg gcaaaacaat gattaaacaa
     1141 actattgtcg cattgatttt gagtgtgggg gcgtcatcgg tcttcgcggc gggaaccgtc
     1201 aaggtattca gcaatggcag cagtgatgcc aaaacgctga cgggtgcaga gcatttaatc
     1261 gatctggtag gccaaccgcg gctggcaaac agctggtggc ctggtgcggt gattagcgaa
     1321 gagctggcca cggcggcagc attgcgtcag cagcaggcgt tgatgacacg gatggcagaa
     1381 ctggccgcag actccagcgc cgacgatgcc gccgcaatta acgccttacg ccagcaaatt
     1441 caggcgttga aagtgacggg caggcaaaaa atcaatcttg atcctgatat cgtccgcgtt
     1501 gccgaacgcg gtaacccgcc gttgcagggc aactacacgc tgtgggtcgg accgccgccg
     1561 tccacggtca cgttgttcgg gcttatcagt cgtcctggca agcagtcatt cactccaggt
     1621 cgcgacgtgg cgagctatct ctctgaccag agcctgctca gcggtgcgga tcgcagctac
     1681 gcgtgggtgg tttacccgga cggacgcacg caaaaagcgc cggtggctta ctggaacaag
     1741 cgtcacgtag agccgatgcc cggcagcatt atttatgttg gcctcgcgga ctccgtctgg
     1801 agtgagacac ctgatgccct taacgccgac attcttcaga ctctgacgca gcggataccc
     1861 caataatgaa aaaaagacat ctgcttagct tactggcgct gggtattagc acagcttgct
     1921 acggcgaaac atatcctgcg cccattggtc cgtcgcaatc ggatttcggt ggcgtaggat
     1981 tattacaaac gcccaccgcg cgcatggcgc gggaagggga gctgagcctg aactatcgcg
     2041 ataacgatca gtaccgttat tactcagctt cagtgcaact cttcccgtgg ctggaaacaa
     2101 cgctgcgcta caccgacgtg cgcacccggc agtacagcag cgtcgaagcg ttctctggcg
     2161 atcaaacgta taaagataaa gccttcgatc tcaaactgcg tttgtgggaa gagagttatt
     2221 ggctgccgca agtggcggtt ggtgcgcggg atatcggcgg tacggggctg tttgatgcgg
     2281 aatatcttgt tgccagcaaa gcctgggggc cgttcgattt tacactcggc ctgggctggg
     2341 gatatctggg caccagcggt aacgtgaaaa atccgctctg ttcagccagt gataaatatt
     2401 gctatcgcga taacagctac aaacaggcgg gatctatcga cggcagccag atgttccacg
     2461 gcccggcctc actgtttggc ggcgtggaat accagacgcc ctagcaaccg ctgcgtctga
     2521 aactggagta tgaaggcaat aattatcagc aggattttgc cggaaagctg gagcaaaaaa
     2581 gtaagtttaa cgtcggggcg atttatcgcg ttaccgattg ggccgacgtt aaccttagct
     2641 atgaacgtgg caacactttt atgtttggcg tcacgctgcg caccaacttt aacgatctgc
     2701 gcccgtctta caacgataac gcccgcccgc aatatcaacc gcagccgcag gatgccattt
     2761 tgcagcattc ggtggtggcg aatcagttaa cgctgttgaa atacaatgcc ggacttgccg
     2821 atccgcagat ccaggcgaaa ggcgatacgc tgtatgttac cggcgagcag gtgaaatatc
     2881 gtgatccgcg cgaagggatc atccgtgcta atcggatcgt gatgaacgat ctgccggatg
     2941 ggataaaaac gatccgcatt acggaaaatc gccttaatat gccacaggtg acgacggaaa
     3001 ccgatgtcgc cagcctgaaa aatcatctcg ccggagagcc gttgggccac gaaacgaagc
     3061 tggcgcaaaa acgcgtcgag ccagtggttc cgaagtccac cgagcagggc tggtatatcg
     3121 acaaatcacg ctttgatttc catatcgatc cggtgctgaa ccagtcgatc ggtggcccgg
     3181 aaaactttta catgtatcag ctgggcgtga tgggaacggc ggatttgtgg ctgacggacc
     3241 atctgctgac cactggcagc ctgtttgcta accttgccaa caactacgac aagtttaact
     3301 acaccaatcc accgcaggac tcgcacttac cgcgcgtgcg tacccatgtg cgcgagtatg
     3361 tgcagaatga tgtctatgtg aataacctgc aagccaacta cttccagcat ctgggcaacg
     3421 gcttctacgg tcaggtctac ggaggttatc tcgaaaccat gtttggcggc gtgggggcag
     3481 aagtgttgta tcgcccgctg gatagcaact gggcgtttgg tctggatgcc aactacgtta
     3541 aacagcgcga ctggcgtagc gcaaaagata tgatgaaatt caccgattac agcgtgaaaa
     3601 ccggacatct gaccgcgtac tggacgccat ctttcgccca ggacgtgtta gtgaaagcga
     3661 gcgtcgggca gtatctggct ggggataaag gcggcacgct ggagatcgct aaacgctttg
     3721 acagcggcgt ggtggttggc ggctatgcca cgatcacgaa tgtttcgaaa gaggagtacg
     3781 gcgaagggga cttcaccaaa ggcgtgtatg tctctgtacc gctggatctc ttctcgtctg
     3841 gcccgacacg cagccgtgcg gcgattggct ggacgccgct gacgcgtgac ggtggtcagc
     3901 aacttgggcg taagttccag ttgtatgaca tgaccagcga ccgtagcgtc aatttccgct
     3961 aagtcatggg aaaggtgcca ggtttcgcac tcactggcac ctttattctt aatggcctgt
     4021 cgagccatca ggaacgcagt tcacccccgg tttgcgatct ggtgtgtaaa ggcgaaaaca
     4081 ttctgtcttc ctgtccgtcg atatcggttg caggtctggt tgcctgagcg actgggccat
     4141 cattgggctg gagacattgc tttgcggtag gtcggcttta tcagcagtac cgagcggacc
     4201 agcataagca ggaagaacag agactgataa catcaaagca gcaaaataag gcttcatttt
     4261 taccaccttt atcaggttac gtttcatttg ttccagagga acattgtcga tttttcgcgc
     4321 attgctggtg gctgggaatc acctgaatgg gtgatttttt tgggctgtgt gttttgccag
     4381 atgagacatt gatgggagat gcccacttaa ttgagctgaa caaaacatac acaaaaaata
     4441 tagatctccg tcacattttt gcgttataca ggaagctcgc cactgtgaag gaggtactgc
     4501 tatgacgtca ctctctcgtc cgcgcgtgga gtttatctcc accattttgc agaccgtact
     4561 caatcttggc ctgttgtgcc tcggcctgat tttggttgtc ttcctcggca aagaaacggt
     4621 gcatctggct gatgtgctgt tcgcgccaga acaaaccagt aaatatgagc tggtagaagg
     4681 tctggtggtt tactttctct atttcgaatt tatcgcgctg attgtgaagt actttcagtc
     4741 cggttttcac ttcccgctac gttactttgt ctatattggg atcactgcca ttgtgcgctt
     4801 gatcatcgtc gatcataaat cgccactgga tgtgttgatc tactcggcag cgatcctgtt
     4861 actggtgatc accctgtggt tgtgtaattc gaaacggctg aagcgggagt aaaaaaaggc
     4921 gctccgtgga gcgccgaata acagtcacaa gttgggataa cgtaagttga gggtgcagcg
     4981 gcataacatt ggcagaacaa catctttaac ctttcacacc acctgccgtc aggccgttga
     5041 ccagccagcg ttgagccagc aagaagacga tggtgatcgg taatgcagac atcacggcag
     5101 cggcggcaaa gtcaccccac aggtagtttt gcgggttgag gtattgctgc atccccacgg
     5161 ccagggtgta gctgtttacg tcacgcagta atagcgacgc gaccggaact tcagtaatgg
     5221 cagcgataaa cgacaggatg aacacaaccg ccagaatcgg tactgacagc ggcaacagga
     5281 caaggcggaa ggcctgccac ggtgtcgcac catccagcgc cgccgcttct tccagcgaac
     5341 tgtcgatggt ttcgaaataa cctttgatgg tccagacatg cagcgcaatc ccgcccagat
     5401 acgcgaaaat tacgccgccg tgagtattca ggccaatgaa tggaatgtac tcacccagac
     5461 gatcaaacaa cgcatacaac gcgaccagtg aaagtactgc cgggaacatc tggaaaatca
     5521 gcattccttt cagcagcgtc gctttgcctg gaaagcgcat acgggcgaaa gcgtaggcgc
     5581 aggtggtgga gagcgccaca atgccaatcg cggaaatccc ggcgaccttt accgagttcc
     5641 acagccacag cagtaccggg aatggcggtg gcgtaatgcg accatcagcc tgttccacgc
     5701 taaaacctaa cgccagtttc cagtgatccc aggagatttg ctccgggatc agactaccgg
     5761 tcgcgaagtt cccctgacgc agcgagatgg cgacgaccat cagcagcggg aacataattg
     5821 ccgcgataaa aagtagcagt agcaggtgag taataaacaa acgtgctttt tgcgatttcg
     5881 gttggaccat tgccattttt gttatctccc ttaatcaaac ttcattcgcg tggctttcag
     5941 gttcactatc gccagcgcgc ccaccagcag gaagatcagc gtggcaattg ctgctgccag
     6001 accgaagtcc tgacccccgc cgccttcaaa agcgatacgg taggtgtagt taacaagcag
     6061 gtcggtataa ccggctggcg tggtcgtgcc aagacgatcc gggccgccgt tggttaacag
     6121 ttgaatcagc acgaagttgt taaagttaaa ggcgaagctg gcgatcatca gcggcgtcag
     6181 cggtttaatc agcagcggca gcgtaatctt aaagaagttc tggaatggac ctgcgccatc
     6241 cattgctgag gcttcataca aatcgtccgg aatcgctttc agcaagccca tgcagaggat
     6301 catcatgtac ggataaccca gccaggtgtt gacgataatc agcatcgtgc gggcggtggt
     6361 cggatcgctg aaccaggcgg gcttcacgcc aaacagcgcg ctcaacatca tgttgatttc
     6421 accaaaactc tggttaaaca accctttgaa aatcaagatt gaaatgaacg atggcaccgc
     6481 gtagggcaga atcagcagga cgcgatagac cgctttgccg cgcaacgctt cccactgcac
     6541 cagacacgcc agaaccatgc cgaccgccac cgttaaaaag acagtgatca gcgagaacac
     6601 cacggtccag acgaaaatgg cgaggaacgg tttctgaatg ccttcgtcgg taaagacgcg
     6661 ggtaaagttt ttccagccgg tggtcacggt gtaaccgggg cttagctttt catcacccca
     6721 gttaccgtcg gcagtgatgg actggtaaaa accaatctgg tcgtttggac gatattttac
     6781 gccactctga ttattggtca gcgtgccgtc accgtcgagt gtgtagagcg gctgcgtgcc
     6841 agaaaactgg cgcagggagc tcatcatcac tttgttgcca tccggcagaa tggcggtaat
     6901 gtcactcagt gcctgacgat tctgggtaat tacgcgcaga ttcgcgcgtt cgccttcggg
     6961 ctgggcggtc gtttctttca gttgcagttt ttgctcgccg ccaaatttaa aagcgtcgga
     7021 gaggtaattt ttgccggttt cgccgtcgct gagcgccagt tgccactcat cgcccgccgg
     7081 ataaagacca aaattataga ttttgcctgc ttgccaggag cgatctagca acacttcctg
     7141 cgcacgttca aaagtcagct ggttagtgct gctgtagttg gtgaaggcaa tggcgatggt
     7201 gcagaccaga gggaagagga cgaataatcc cattccagcc attcccgggt aaacatagcg
     7261 ccaggcgtag gctttacgat tggcgaaaat atacagcccc gctgagctca atatcagcgt
     7321 ggtaatggcg aacaggtatt ccccttgtgc gtacattaaa acaacaaggt aacccaccag
     7381 caggccgagc agacctaaca ctgaccattt cagcgcgtcg ctttgccacc aatgtttctt
     7441 tttaatgaca tccatggggt tcttcctcat tccaggacgg ataaggcttt cataccttat
     7501 ccgacaacaa ctgcctgatg cgacgctgac gcgtcttatc aggcctacat acgtttcaat
     7561 ttcgtaggcc ggataaggcg ttcacgccgc atccggcatt tcacagcatt acttggtgat
     7621 acgagtctgt gcatctttca gcgcagcatc cacagtctga cgaccgctgg cggcgttgat
     7681 caccgcagta cgcacggcat accagaaagc ggacatctgc gggatgttcg gcataatttc
     7741 acctttctga gcgttatcca tggtggcggc aatacgtgga tctttcgcaa gttcatcctg
     7801 ataggacttc agcgctactg cacccagcgg tttgtcttta ttgaccgctt ccagaccttc
     7861 gtcagtcagc agatagtttt cgaggaactc tttcgccagc tctttgttcg gactggcggc
     7921 gttaatacct gcgctcagca cgccaacgaa cggtttagat ggttgacctt tgaaggtcgg
     7981 cagtaccgtt acaccataat tcactttact ggtgtcgatg ttggaccatg cccacgggcc
     8041 gttgatagtc atcgctgttt cgcctttatt aaaggcagct tctgcgatgg agtaatcggt
     8101 gtctgcattc atgtgtttgt ttttaatcag atcaaccagg aaggtcagac ccgctttcgc
     8161 gccagcgtta tccacgccta cgtctttaat gtcgtacttg ccgttttcgt acttgaacgc
     8221 ataacccccg tcagccgcaa ttagcggcca ggtgaagtat ggttcttgca ggttgaacat
     8281 cagcgcgctc ttacctttcg ctttcagttc tttatccagc gccgggatct cttcccaggt
     8341 ttttggcggg ttcggcagca gatctttgtt ataaatcagt gataacgctt cgacagcgat
     8401 cgggtaagca atcaacttgc cgttgtaacg tacggcatcc caggtaaacg gatacagctt
     8461 gtcctggaac gctttgtccg gggtgatttc agccaacagg ccagattgag catagccacc
     8521 aaagcggtcg tgcgcccaga agataatgtc agggccatcg ccagttgccg caacctgagg
     8581 gaatttctct tccagtttat ccggatgctc aacggtgact ttaattccgg tatctgtctc
     8641 gaatttctta ccgacttcag cgagaccgtt atagccttta tcgccgttaa tccagattac
     8701 cagtttacct tcttcgattt tggcgagagc cgaggcggaa aacatcatcg tcgttaatgc
     8761 ggataatgcg aggatgcgtg cacctgtttt tattttcata atctatggtc cttgttggtg
     8821 aagtgctcgt gaaaacacct aaacggactc tagtttcttt atacggcaac ctctttccat
     8881 cctccttgcc cctacgcccc atcgttgctt tgtgtgatct ctgttacaga attggcggta
     8941 atgtggagat gcgcacataa aatcgccacg atttttgcaa gcaacatcac gaaattcctt
     9001 acatgacctc ggtttagttc acagaagccg cgttctcatc ctcccgcctc ctcccccata
     9061 aaaaagccag ggggtggagg atttaagcca tctcctgatg acgcatagtc agcccatcat
     9121 gaatgttgct gtcgatgaca ggttgttaca aagggagaag ggcatggcga gcgtacagct
     9181 gcaaaatgta acgaaagcct ggggcgaggt cgtggtatcg aaagatatca atctcgatat
     9241 ccatgaaggt gaattcgtgg tgtttgtcgg accgtctggc tgcggtaaat cgactttact
     9301 gcgcatgatt gccgggcttg agacgatcac cagcggcgac ctgttcatcg gtgagaaacg
     9361 gatgaatgac actccgcctg cagaacgcgg cgttggtatg gtgtttcagt cttacgcgct
     9421 ctatccccac ctgtcagtag cagaaaacat gtcatttggc ctgaaactgg ctggcgcgaa
     9481 aaaagaagtg attaaccagc gagttaacca ggttgcggaa gtgctgcaac tggcgcattt
     9541 gctggatcgc aaaccgaaag cgctctccgg tggtcagcgt cagcgtgtgg cgattggccg
     9601 tacgctggtg gccgagccaa gcgtattttt gctcgatgaa ccgctctcca acctcgatgc
     9661 tgcactgcgt gtgcaaatgc gtatcgaaat ctcccgtctg cataaacgcc tgggccgcac
     9721 aatgatttac gtcacccacg atcaggtcga agcgatgacg ctggccgaca aaatcgtggt
     9781 gctggacgct ggtcgcgtgg cgcaggttgg gaaaccgctg gagctgtatc actatccggc
     9841 agaccgtttt gtcgccggat ttatcggttc gccaaagatg aacttcctgc cagtaaaagt
     9901 gaccgccacc gcaatcgatc aagtgcaggt ggagctgccg atgccgaatc gtcagcaagt
     9961 ctggctaccg gtcgaaagcc gtgatgtcca ggtgggagcc aatatgtcgc tgggtattcg
    10021 cccggagcat ctactgccga gtgatatcgc tgacgtcatc cttgagggtg aagttcaggt
    10081 cgtcgagcaa ctcggcaacg aaacgcaaat ccatatccag atcccttcca ttcgtcaaaa
    10141 cctggtgtac cgccagaacg acgtggtgtt ggtagaagaa ggtgccacat tcgctatcgg
    10201 cctgccgcca gagcgttgcc atctgttccg tgaggatggc actgcatgtc gtcgactgca
    10261 taaggagccg ggcgtttaag caccccacaa aacacacaaa gcctgtcaca ggtgatgtga
    10321 aaaaagaaaa gcaatgactc aggagataga atgatgatta ctctgcgcaa acttcctctg
    10381 gcggttgccg tcgcagcggg cgtaatgtct gctcaggcaa tggctgttga tttccacggc
    10441 tatgcacgtt ccggtattgg ctggacaggt agcggcggcg aacaacagtg tttccagact
    10501 accggtgctc aaagtaaata ccgtcttggc aacgaatgtg aaacttatgc tgaattaaaa
    10561 ttgggtcagg aagtgtggaa agagggcgat aagagcttct atttcgacac taacgtggcc
    10621 tattccgtcg cgcaacagaa tgactgggaa gctaccgatc cggctttccg tgaagcaaac
    10681 gtgcagggta aaaacctgat cgaatggctg ccaggctcca ccatctgggc aggtaagcgc
    10741 ttctaccaac gtcatgacgt tcatatgatc gacttctact actgggatat ttctggtcct
    10801 ggtgccggtc tggaaaacat cgatgttggc ttcggtaaac tctctctggc agcaacccgc
    10861 tcctctgaag cggggggttc ttcctctttc gccagcaaca atatttatga ctataccaac
    10921 gaaaccgcga acgacgtttt cgatgtgcgt ttagcgcaga tggaaatcaa cccgggcggc
    10981 acattagaac tgggtgtcga ctacggtcgt gccaacctgc gtgataacta tcgtctggtt
    11041 gatggcgcat cgaaagacgg ctggttattc actgctgaac atactcagag tgtcctgaag
    11101 ggctttaaca agtttgttgt tcagtacgct actgactcga tgacctcgca gggtaaaggt
    11161 ctgtcgcagg gttctggcgt cgcgtttgat aacgaaaaat ttgcctacaa tatcaataac
    11221 aacggtcaca tgctgcgtat cctcgaccac ggtgcgatct ccatgggcga caactgggac
    11281 atgatgtacg tgggtatgta ccaggatatc aactgggata acgacaacgg caccaagtgg
    11341 tggaccgtcg gtattcgccc gatgtacaag tggacgccaa tcatgagcac cgtgatggaa
    11401 atcggctacg acaacgtcga atcccagcgc accggcgaca agaacaatca gtacaaaatt
    11461 accctcgcac aacaatggca ggctggcgac agcatctggt cacgcccggc tattcgtgtc
    11521 ttcgcaacct acgccaagtg ggatgagaaa tggggttatg actacaccgg tagctcttca
    11581 accaacccat actacggcaa ggctgtgtcg gctgatttca atggcggtag cttcggtcgt
    11641 ggcgacagcg acgagtggac cttcggtgct cagatggaaa tctggtggta atagcaaaaa
    11701 actgggccgg ataaggtgtt tgcaccgcat ccggcaatca atgcctgatg cgacgctgtt
    11761 gcgtcttatc aggcctacaa ccgctgccga aagtaggccg gataaggcgt ttacgccgca
    11821 tccggcataa aaacagcttt aaggggcgaa agcccctctg attatcgggt ttagcgcgct
    11881 attgcctggc taccgctgag ctccagattt tgaggtgaaa acaatgaaaa tgaataaaag
    11941 tctcatcgct ctctgtttat cagcagggtt gctggcaagc gcacctggaa tcagccttgc
    12001 cgatgttaac tacgtaccgc aaaacaccag cgacgcgcca gccattccat ctgccgcgct
    12061 gcaacaactc acctggacac cggtcgatca atctaaaacc cagacgactc aactgtcgac
    12121 cggcggccaa caactgaacg tttccggcat cagtggtccg gttgctgcgt acagcgtccc
    12181 ggcaaacatt ggtgaactga cactgacgct gaccagcgaa gtgaacaaac aaaccagcgt
    12241 atttgcgccg aacgtgctga ttcttgatca gaacatgacc ccatcagcct tcttccccag
    12301 cagttatttc acctaccagg aacccggcgt gatgagtgca gatcgtctgg aaggcgttat
    12361 gcgcctgaca ccggcactgg ggcaacagaa actctatgta ctggtcttca ccacggaaaa
    12421 agatctccag cagacaaccc aactgctcga cccggcaaaa gcctatgcca aaggcgtagg
    12481 taactcggtg ccggatattc ctgacccgat tgcccgtcac accactgatg gtttgctgaa
    12541 actgaaagtg aaaacgaact ccagctccag cgtgttggta ggaccactat ttggttcttc
    12601 cgctccagct ccggttacgg taggtaacac ggcggcacca gctgtggctg cacccgctcc
    12661 ggcaccggtg aagaaaagcg agccgatgct caacgacacg gaaagttatt ttaataccgc
    12721 gatcaaaaac gctgtcgcga aaggtgatgt tgataaggcg ttaaaactgc ttgatgaagc
    12781 tgaacgcctg gggtcgacat ctgcccgttc cacctttatc agcagtgtaa aaggcaaggg
    12841 gtaattacgc tccacagtgc tgattttgca acaactggtg cgtctcctgg cgcacctttt
    12901 tttctcctcc tgtactattg ttgcgttttt gttgcgcatt agttcactta atttgcttta
    12961 catctcccgt aaatattttt ctgcgataca atgcctttac gttatgtaac ggagagttcg
    13021 gcatgtcaca ccccgcgtta acgcaactgc gtgcgctgcg ctattttaca gagatccctg
    13081 ccctggagcc gcaactgctc gactggctgt tgctggaaga ttccatgaca aaacgttttg
    13141 aacagcaggg aaaaacggtg agcgtgacga tgatccgcga agggtttgtc gagcagaatg
    13201 aaatccccga agaactgcca ctgctgccga aagagtctcg ttactggtta cgtgaaattt
    13261 tgttatgtgc cgatggtgaa ccgtggcttg ccggtcgtac cgtcgttcct gtgtcaacgt
    13321 taagcgggcc ggagctggcg ttacaaaaat taggtaaaac gccgttagga cgctatctgt
    13381 tcacatcatc gacattaacc cgggacttta ttgagatagg ccgtgatgcc ggactgtggg
    13441 ggcgacgttc ccgcctgcga ttaagcggta aaccgctgtt gctaacagaa ctgtttttac
    13501 cggcgtcacc gttgtactaa gaggaaaaaa atatggagtg gagtctgacg cagaataagc
    13561 tgctggcgtt tcatcgctta atgcgtacgg ataagccaat tggcgcgtta ctgctgctct
    13621 ggccaacatt atgggcgttg tgggtggcga caccgggcgt tccccagctc tggatcctgg
    13681 cggtgtttgt cgcgggcgtc tggctgatgc gcgctgctgg ttgcgtggtg aatgattatg
    13741 ctgaccgcaa gtttgatggt catgttaagc gcacggcgaa ccgaccactt cccagcggcg
    13801 cggtgacaga gaaagaagcg cgtacgctgt ttgtagtgct ggtactgatt tcatttttac
    13861 tggtgctgac gctgaatacg atgactattc tgttgtcaat tgccgcgctg gcgctggcgt
    13921 gggtataccc gtttatgaag cggtataccc atctaccgca agtggtgctg ggcgcggcgt
    13981 ttggctggtc gattccaatg gcttttgccg ctgtgagtga gtcggtgcca ttgagttgct
    14041 ggttaatgtt cctcgccaat attctctggg cggtggctta cgacacgcag tatgcgatgg
    14101 ttgaccgcga tgatgatgtg aagattggca ttaaatccac cgcaatcctg ttcggccaat
    14161 acgataaatt gattattggt attttgcaga ttggcgtact agcgctgatg gcgatcatcg
    14221 gtgagttaaa tggcttaggc tggggatatt actggtcaat tctggtagct ggcgcgctgt
    14281 ttgtttatca acaaaaactg attgccaacc gcgagcgtga agcctgcttt aaagcattta
    14341 tgaataataa ctatgttggt ctggtactgt ttttagggct ggcaatgagt tactggcatt
    14401 tctgatgatg taaaaaagcc ggatgatcat ccggctttct tctgggttgc ctgatgcgct
    14461 gcgcttctca ggcctacaca acatatcgca atttattgaa tttgcagatc atggtaggcc
    14521 gaataaggcg tttgcgtcgc atccggcaat tctcactgat tacccttcgc cctgcgtcgc
    14581 actctcaatc gtcaaacgca cgtctgatgt aatcaactcc gccagcaact gatatacctt
    14641 catcgtttct gccggttcgg cgtcgccgct atcgctgata tacccttcat cacgcagcgt
    14701 cagcaccaga gaactgaaca ccgccttgtc gaagaattcc ggcgcgttga taccgtgcag
    14761 cacggagaga cgttgcgcga cggtgcggct ctctttttcc agcgtaccgc ggttgatcga
    14821 cgggttggca ctcaacagcc agaaggtgat ggcataacgt tgcagcgttt cgcgcgcgcc
    14881 tgcggccagc agctgtagcg tgcgagaatg cgccgggttg atatgcaact catcatcttg
    14941 cagggtaatc agcccctgac gttgcatctc atttgccagc gcatcaataa cgtccggtaa
    15001 ctcgtcgcga tcccagcgca ggaacagttc cgctttcagc attgggtaaa gcacattgac
    15061 gtgctccatc aatacgtcgc gggagatgtg gcgatgctgg gtgacaattg ccgccatcag
    15121 cgaaggcagc accaacatat gcgcaatgtt gttgcgatag taggtcatca gcaccgcttg
    15181 ctcgcgcggc agaatgatga tgtcgccgat agtgtctttc tcgacttcaa acttgttcat
    15241 ttgcagcgcg tgatcgataa gctcgctggc gctggctgaa ggaacggtag agtccgtgga
    15301 gtaaggcacg ttgcgcatca gatccaggta gcagttgagt tgcttggtta actgctcgcg
    15361 ggtgagtgag cgctgacgtg acgccagaag cgcagtacag cacaggttca tggcgttcgc
    15421 cgcgcctgcg ttgttaatgc gtaccatcag atcggcagca atattattga ccgtcggcgt
    15481 taaccaggcc ggacgcaccg cttcgatggg atcgatagat tcacgccagt ctggtacgtg
    15541 ctggttaagg taggtcatca acggcattgg ttcaccgaag ttgacgtaac cctgaccgag
    15601 attacgcagc ttgcttaaac cgcgcagcat ctgcggcagg ctctctttct ctttcgtcgc
    15661 accgcgcagt tctttggcgt aagtacccac ttccatgacg tgctcataac cgatatagat
    15721 cggaatcagc gtaatcggac gagtgccgcc acgcagcatc gcctgaatgg tcatcgatag
    15781 cgtaccggtt ttcggatcca gcaaacgccc cgtacgggaa cgaccgcctt ccacgaaata
    15841 ctcgacggaa taaccacggc tgaacagttc gccgagatac tcacggaaaa cggtggaata
    15901 aagtttattg cctttaaacg tacggcgaat aaagaacgcc cccagacggc ggaaaatcgg
    15961 cccggccggc cagaagttca ggttgatccc ggcggcgata tgcggcggca ccagcccctg
    16021 gtgatacagc acgtaagaaa gcagcaggta gtccatgtga ctgcggtggc aaggcacata
    16081 cactagctca tggccgtcgt gggccagctg gcgaacgcgc tcggcgttat ggacgttgat
    16141 accctggtaa agtcggttcc aggtgaagcc cagaatgcgg tcagtcaggc ggatcatctc
    16201 gtaagagaaa ttcgccgcaa tctcttccat cagcgcaatc gcgttctgct gcgctttttc
    16261 atgggagatt tttttgctgc gtgcttcatc ttctaccgct ttcgcaatgg cgcgggaggc
    16321 gagcagctta ttaaacagat cctgacgagc aggcagacgt ggacccacgg cagccagacg
    16381 ttgacgggca aagtgcatac gcgccacgcg cgccagtttc tgagcgatag ttttatccgt
    16441 gccgtgttca tccgccatac ggcgcagtga aactgacggc gagaaacgca caaaactgtc
    16501 gcgaccgagc cacagtacag cgaaaaattt ctgtacgccg ttaagcatac gcagcggcgg
    16561 gttcacttcg cctttttcac gccccggcgc gcgaccaaac atcaccgata ctggcaccat
    16621 ctgcacatcc agatttgggt tgctgcggtg caaatcgaga tagtcgtgga acagcttaat
    16681 agactcttct ttcggcgtgt aataggtgaa cacacgcggc ccgccgtgaa tgaacacata
    16741 gcgcggcagt agcgtgccgt cgatttccag cggttctaac gggtcaggca ggtcatgtgc
    16801 cagacactgg gcgcgcaacg tcagcaagtc agctttcgag ttgtacggta aaacgtacat
    16861 aattggacga gaggtatcca gccccagttc cggggcagga tccgccggaa tagacttgct
    16921 ttttaccagg atgcttaatg gtaaattcag taatttgtag taaattcgtg gccagccgga
    16981 cataaacgat gtaaagcctc tggttaataa tgcaaatgcg cggcaaggat agcagaaagt
    17041 catgggaaat tctgtggtat ccgctcatgt ttcgcgcggc gttacgcaaa cccgaatcat
    17101 cggatttaac ggtacactga tattgacgct cataatgtaa aaaggttctt tcaatggcca
    17161 ataataccac tggattcatc cgaattatta aagctgctgg ctattcctgg aaaggtttac
    17221 gcgctgcatg gatcaacgaa gcggcattcc gtcaggaagg cgtagcggta ttgttagcgg
    17281 tggttatcgc ctgctggctg gatgtggacg cgattacccg cgtgctgctt atcagctccg
    17341 tgatgctggt gatgattgtg gaaattctca atagcgccat cgaagctgtg gttgaccgaa
    17401 ttggctctga ataccatgag ctttccggac gcgctaaaga tatgggatct gccgcagtgc
    17461 tgattgccat tatcgtcgcc gtgattacct ggtgcatcct gttatggtcg cattttggat
    17521 aacccttcca gatttcgata aatctctggt ttattgtgca gtttatggtt ccaaaatcgc
    17581 cttttgctgt atatactcac agcataactg tatatacacc cagggggcgg aatgaaagcg
    17641 ttaacggcca ggcaacaaga ggtgtttgat ctcatccgtg atcacatcag ccagacaggt
    17701 atgccgccga cgcgtgcgga aatcgcgcag cgtttggggt tccgttcccc aaacgcggct
    17761 gaagaacatc tgaaggcgct ggcacgcaaa ggcgttattg aaattgtttc cggcgcatca
    17821 cgcgggattc gtttattgca ggaagaggaa gaagggttgc cgctggtagg tcgtgtggct
    17881 gccggtgaac cgcttctggc gcaacagcat attgaaggtc attatcaggt cgatccttcc
    17941 ttgttcaagc cgaatgctga tttcctgctg cgtgtcagcg ggatgtcgat gaaagatatc
    18001 ggcattatgg atggcgattt gctggcagtg cataaaactc aggatgtacg taacggtcag
    18061 gtcgttgtcg cacgtattga tgacgaagtt accgttaaac gcctgaaaaa acagggcaat
    18121 aaagtcgaac tgttgccaga aaacagcgag tttaaaccaa ttgtcgttga ccttcgtcag
    18181 cagagcttca ccattgaggg gctggcggtt ggggttattc gcaacggcga ctggctgtaa
    18241 catatctctg agaccgcgat gccgcctggc gtcgcggttt gtttttcatc tctcttcatc
    18301 aggcttgtct gcatggcatt cctcacttca tctgataaag cactctggca tctcgcctta
    18361 cccatgattt tctccaatat caccgttccg ttgctgggac tggtcgatac ggcggtaatt
    18421 ggtcatcttg atagtccggt ttatttaggc ggcgtggcgg ttggtgcaac ggcgaccagc
    18481 tttctcttta tgttgttgct gtttttacgc atgagcacca ccgggctgac tgcacaggct
    18541 tatggtgcca aaaatcctca ggcattagcc cgtgcgctgg tgcaaccgtt gctgttggcg
    18601 ttgggggccg gggcgttaat tgcgctgctg cgtacgccga ttatcgatct ggcgctgcat
    18661 attgttggtg gtagtgaagc agtcctggaa caggcgcgac gctttcttga aatccgctgg
    18721 ttaagcgcac cggcgtcgct ggcgaatctg gtattacttg gctggttact cggcgtgcaa
    18781 tatgcccgtg cgccagtaat tttgttagtg gtcggcaata tcctcaacat tgtgctggat
    18841 gtctggctgg tgatggggct gcatatgaac gtgcagggcg cggctctggc gacggttatt
    18901 gcggaatatg caacattgct gattggtctg ctaatggtgc gtaaaattct caaactacgc
    18961 ggaatctccg gcgaaatgct gaaaacagcc tggcgaggaa acttccgtca cttgctggcg
    19021 cttaaccgcg atatcatgct gcgctcgctg ttgctgcaac tctgtttcgg cgcgatcact
    19081 gtacttggcg cgcgactggg gagtgacatt atcgctgtta acgcggttct gatgacgcta
    19141 ctcaccttta ccgcctatgc gctggatggt tttgcctacg cggttgaagc acattccggt
    19201 caggcatacg gtgcgcgcga cggtagtcaa ttgctggatg tctggcgggc agcgtgccgc
    19261 cagtcgggga tcgtagcgtt actgttttcg gtggtttatt tgctggcagg ggaacacatc
    19321 attgcgttgc tgacgtcgtt aacccagatt cagcagctgg ctgaccgcta tcttatctgg
    19381 caggtgattt tgccgttggt cggcgtctgg tgttatctgc tggacggcat gtttataggc
    19441 gcaacgcgtg ccgccgaaat gcgtaacagt atggcggtgg ccgccgcagg ttttgcactg
    19501 acgctcctta cgctgccgtg gctggggaat catggtttgt ggctggcgtt aaccgtcttt
    19561 ctggcgttac gcgggctttc tctggcggct atctggcggc gtcactggcg taacgatacc
    19621 tggtttgtcg caacgtgacg gttaaaaatt ctgaataaat aatcctaagc caaattgctg
    19681 actacactta atctcacgtt cagaagaaaa gtgaacgtac tctcattcac aacctaacga
    19741 tgaggtcttg attatgaata aagatgaagc cggcggtaac tggaaacagt ttaaaggtaa
    19801 agtgaaagag caatggggca aactgaccga tgatgatatg acgatcattg aaggaaaacg
    19861 tgatcagtta gtgggtaaaa tccaggaacg ctacggttat cagaaagatc aggcagaaaa
    19921 agaggttgat agttgggaaa aacgccatga ttaccgctgg taattaatcc ctcctgcccg
    19981 acatgtacaa ggatgtacac ccttttagcg aggtttcttt ttcacctgaa tagagtggtc
    20041 atgatggcac tgttcaggat gacgacacgc ttctacttct acacatgctg aacataatcc
    20101 atgtgcttca ataacattat gccgcagggc aaaacccatt tttgccgcca gcgtatgcat
    20161 gatgtcttcc acgccttcag cacattcttc tttcaccgcg ccgcagcgat cgcaaataaa
    20221 catggctgaa gtatgggtgg gctgatcgaa cagatgacag agcacataac tgttggtgga
    20281 ttccacctta tgcacaaaac cttgttcaag cagaaactcc agcgcgcgat aaaccgttgg
    20341 cggcttggct tgcggttcag cttcgcgcag caaatcaagc agatcataag cgctgatagc
    20401 gccatcctgc agactcatca ggcgcaacac ttcgagacgc tgtggggtca ggcgcacatt
    20461 acgctgtgcg cagatttttt cagcctgcgc taataactcc tgcgttgtgg tcttttccat
    20521 tgggcacctc gacagtgggg ttaagaatgt ccttacttta ccatagttct cacttaaacg
    20581 ccgagaacag ggtgtcatgg ctgtcacatt gcctgatcgc atattcgtta tgctatagta
    20641 gcgcccccaa tttaccagat gcttaaaaag tcgccatgcc agcagaatca cacactgttt
    20701 atcccgctta ccgtttctcg attgccccga tgcttgactg gacggacaga cattgccgtt
    20761 atttcctgcg tctgctttcc cgcaatacgt tgctgtatac cgaaatggtg accacagggg
    20821 cgattattca cggtaaaggt gattacctgg cgtacagtga agaagaacat ccggtagcgt
    20881 tgcaactcgg gggtagcgat ccggcggcgc tggcacagtg tgcgaagctg gcagaagcgc
    20941 gcggatatga tgagatcaac ctgaatgtcg gctgcccgtc tgaccgggtg cagaacggca
    21001 tgtttggtgc gtgtctgatg ggtaatgcgc agctggttgc cgactgcgtg aaagcgatgc
    21061 gcgatgtggt gtcgattccg gtgacggtga aaacgcgtat tggcatcgat gatcaggaca
    21121 gctatgaatt tctctgcgat ttcatcaaca ccgtttccgg caaaggtgag tgtgagatgt
    21181 tcatcatcca cgcacgtaaa gcctggcttt ctgggttaag tccgaaagaa aaccgtgaga
    21241 tcccgccgct cgattatccg cgtgtgtatc aactgaagcg tgactttccg catctgacga
    21301 tgtcgattaa cggtggtatc aagtcgctgg aagaagctaa agcgcatttg caacatatgg
    21361 atggcgtgat ggtcgggcgc gaggcgtatc agaatccggg gattctggcg gcggtagacc
    21421 gagagatttt tggttcctcg gataccgatg ccgatccggt ggcggtagtg cgcgccatgt
    21481 atccgtacat tgagcgtgaa ctcagccagg ggacgtatct cggccatatt acccggcata
    21541 tgctgggctt gttccagggt attcctggcg cgcggcagtg gcgacgttat ttaagtgaaa
    21601 atgcccataa agcgggtgca gacattaatg tgctggaaca cgcgctcaaa ctggtggcgg
    21661 ataagcgtta acttttcacc aaaaagtagt caaattcacc acgccctgcg caccgtcgcg
    21721 gggcgttttg ctgttaaatc aatagattat ttttggcatg attcttgtaa tgccagcaag
    21781 agatttcata tttgggagag catcatgctg gaactacttt ttgtaattgg cttttttgtc
    21841 atgctgatgg tcactggtgt ttcgttgctg ggtattatcg ccgcgctgat tgtggcgacg
    21901 gcctttatgt tcctcggcgg tatgctggca ttgatgatta agttgctgcc gtggctgctg
    21961 ttggcggttg cggtggtgtg ggtgatcagg gcgattaaag caccaaaagt gccgaaatat
    22021 cagcattatg accgctggcg ttactaaggg attgtgcgga tgatcacaac ctaaggtttt
    22081 atccttagaa caaaatagga attgataatc aaatctgtca ctattgcgtg tcaaacaaat
    22141 tcatcgagct gtaccctaca tacagccgaa ctataaaaga aagggcttcc caggtggaag
    22201 cccaatttct tttatggaat caacaggctg gaaccctgcg tcgcccggct ttccagaatc
    22261 tcatgcgcac gccgcgcatc cttcagcgga tatttctgct gctcggcgac atcgacctta
    22321 atcacaccgc tggcaatcaa agagaacagt tcattactgg cctcggttaa ttcctcccgc
    22381 gtggtgatat agccttgcag ggaagggcgt gtcacataca acgagccttt ctgattgaga
    22441 atgcctaagt tcacaccggt aaccgcacct gatgagttgc caaaactcac cattaagccg
    22501 cggcgttgca ggcaatccag cgaccgttcc caggtgtctc tgcccactga atcgtacacc
    22561 acgcgcactt tcttgccacc ggtgatctct tttaaccgct cgaccagatt ctcttcacga
    22621 tagttaataa cctgccatgc gcccgctttt agcgcactct gcgctttttg cgcggttccc
    22681 acggtgccga taagtttcgc gcccagggct tttgcccact ggcaggcaat caagccaacg
    22741 ccgccagccg ctgcgtggaa caggaactgt tcatcgggtt taatttcata ggttttgcgc
    22801 agcagataat aaaccgttaa gcctttcagg aaggatgccg cagcttgctc aaaagaaatt
    22861 gccgcaggca gaatcgccgc tttatccgca ttaatgttat gcatagagct gtaagcgcct
    22921 aatgccgatt gtgcatagac tacgcgatcg cctgccttaa tatgctttac accactgccg
    22981 actttactca cgatgcctgc cgcttcggtg cctaatccgc tgggtagcga tggtggcggg
    23041 taaaggccgc tgcggatata cgtgtcgata aaattgatgc cgatggcttt atttttgacc
    23101 tggatttcat tctccgccgg atcggcagga gtgaactcca cggcctgaag tacttccggg
    23161 ccaccgtgct tgtgaaattc gatgcgcgtt gccatttaaa ctcctttact gagcgacata
    23221 tctgttttaa gcctaacagt agtcgccagg ccgcgcgggg attttttccg ggctgcggtc
    23281 acaacccgga atatctctga tcagtattga aacggcgtcg ccgcaatcca gttttgccac
    23341 tggcgctcaa agttggttag cgttaatacg ccccgttcac ggcacgggcg agtccaggtt
    23401 tggtaatcat tagcttcccg acaaacacaa atcatatatt gcctggcatc ctgattttct
    23461 ggccgaaaac gccaggccag gagtggccca cctggtgttt gcggtgcaat accggcttcg
    23521 ccatcataga tagccctggc accacgactc ccaccaccgt tttcgacata acattgtaaa
    23581 gaacgcagta cagccagcgc cagttgcgca ctttgccgcc actggaaaga ttgtgccagg
    23641 ctgttttcat cgcattgaat accttcccgg cgaatatctt cacaaagtgt tgccagggtt
    23701 tgcgcggcag tgttgatccc ctgtgtatga cacaaaattg cggcatggtg gctcatggta
    23761 ttttgtatcg tttctcgcac gtcgtcacgt agcagcccct gattcaggta ctgttgcgcc
    23821 tcattaatcg tactgagaat ttgttgcctc tcgagaggcc ggtcctggct tttctgatga
    23881 gcaatatgta atgcacagcg gcgggcgaaa acttgcccgg cattgagcgc tgctccacct
    23941 gggcgcgtga caccatgtgt tccggcattt tctccggcag cataacaacc agttagcgat
    24001 gtacgtcccc aaatatcaac ttcaattccg ccattaagat gttgattatt tagcgtaaac
    24061 ttgagcggtg aggctgtgag atcatgaccg tgcatctgat acaaacgaat agccagagga
    24121 ttcatctgtg ttaatctcgc cagcggttgt gccaacaggg cgtgattttg ttgcagatag
    24181 tcgatgacat catcatccag ttcttgcagg ttgaatgacg ttccgtccgc tgcgggttct
    24241 ggttcccgta gaaaatcaag aaaaacatcg cgcccttttt gagtctcttc ataaactgcg
    24301 acatccagca ggctggagcc atattccagc attcgttccg cgtgaaacgg ccactggtaa
    24361 cctttacgaa atattgcgga ggccagcata cgagtcgtgg ggtaataagc tgccagaaaa
    24421 ttatactgac gcccggagtg gtcctgcgaa tagatgcgcg gcatcgcctg catgtaagta
    24481 ccggaaagat tccacggaaa ctggctgcgc ggtgtaccga taccaaactg actttccgta
    24541 agattaacca gagttatacc tgcttccagt gccatgccca acgcactaaa acagttcacc
    24601 ggataaacac tgtcacgata aagttcacct ggtccgcccg tggctaaaac cagatgctgg
    24661 cagcgaatca cgaccattcg ccagggatta tcccgacagg ctttatcgat ggcgatcacc
    24721 cccacgactc gtcgattttc cccttcacca ctggtcagga tatgaatcgc cgttgtgtga
    24781 tcgcaaagag gaatattaag gcgcattgcc tcctgggcca gcaccttcac catcaggcgc
    24841 gatgttcgag gaccgcagct agtggcacgg ccaaattcat cgtgatcggt ttgataacgc
    24901 aacgttgcgc caaagagatc ttcaggcaga tccagaccca gatatttcag tacttcacag
    24961 gtgttcaccg atccgaccgc ctcaacatat gcggtgtcat gatccatcgc accacctgcc
    25021 gccagggtgt tacttaatgt cagaaaatgg tcaccatttg cacgcgtatt cgcggtgtga
    25081 agcgtttgtt tatcggaacc agaacaggcg gaagtgcccc agaaggcttt gctggaggcg
    25141 accattacat cgacattttg ccgtttcagc tcgacggcag ctcgccatcc tgccgcgcca
    25201 ctgcccagaa ccagcgtgtt gcagcagtac tctggtaaaa tggtaccgtt aaggtcgata
    25261 ctaccgctgg cttgagccag cggtgcgtaa tggggcattt tgatatcagt gagcgccgtt
    25321 agcgtttcgt caatcattgc gtcccaccta tttcatcaga ctttcgatta agccgctcat
    25381 tgccatatag cccatgatta gcgtaaatac gcttatggca ataaacatga cgttttccca
    25441 gcgtgagcaa cgatatttgc ccattaacga aggcttgttc gccagccaga acatacataa
    25501 aacagtcagc ggcagaataa tggcgttaaa ggcctggctg gcaatcatca ccaataccgg
    25561 gcgtgcgtgg aacagcggca caaccagaca aagcagagac ataaccgtca tcaggatacg
    25621 gtaacctggg ctaacttcgt tgctggtatc acgccagtca gccagcagcc agggcgttaa
    25681 cagcaaattt gggaactggc tggaaagccc ggctgcaaca ataccaataa caaagagccc
    25741 cacggcagct gagccagcaa taggttcgag aataatgacc atttgcgagg cattatttaa
    25801 acctgtgcca gtttggtaca acgtacccgc agccgcagcc atcaccgccg cactgatgat
    25861 gaacatcatt cctgcactga caatggcatc acgattttga tgaggcaaat tgtccacacc
    25921 ccaaccatta ctttttacca gggtcgtgcg cataagaaac attgctggtg ctacggtggt
    25981 acccaccatg ccagaaatta tcagaaatgg cgtactgtta tcgccagcga caggatcggg
    26041 aacagacgga ataaatccgg ccagcagatc tgcgaccggc ggcatcataa tgaaaaaatt
    26101 aatcacaaac gccagcccca taatgccaac cagcgcggag aggattttgt cgaacccggc
    26161 gttgctgttg gtccagagca tcacgttaat cataatgacc atcgcgatag cccaggcgag
    26221 agctgagata ccgccactaa accaggtcgt ggaccatgtt gccattacat ccgccagaat
    26281 acccattacc cccataatgg aaccgctcac ggcaacggtt aacccgatca gaaacaacat
    26341 cgcaacgccg ggatggatat ggcgacgaaa tgcagtcaac gcgcgttcac cagtgacgga
    26401 agcataacga ccataaatac ggattaaaaa ccaggtaaca atgcaagaaa gcgccacggc
    26461 ccacatgagc gagacaccat agttagcacc tgctttagcc atagtggtga tgctgcctgt
    26521 tccgatgctg tagccaataa gaaagatgcc aggtgcaaag gccgcgagtt ttgtcattat
    26581 tcgccgaaat aaagaaggcg tttggggaac agaggttgtc atattcatta tctttctttc
    26641 cttgtaagag gcgatcagcg tgcctgaaag tgcggttgac gcttctcagt aaatgcctga
    26701 ctgccttcat gagcatcttc agtcgtggcg gaaaaagcgc cagccagtgc ttcaagcgtc
    26761 gaggccacag caataccttc tccggcatca ataacctgct tggcgatctg cactgcaacg
    26821 ggagcacgct gggcgatacg ttgtgccagt tgcagtccgg cgtcgtgtaa cgcctccctg
    26881 gcgacaacgc gattcaccag cccgcaggac agtgcccgct gtgcatccag tggttcaccg
    26941 gtaaatacca gttctttcac cagtgagcgc ccaagcagtg ccgtcagccg ctgcgttcct
    27001 gaccagccag gcactgtcgc cagcccggtt tctggtagtg ccatttgtgc ttcggcgcta
    27061 caaatacgga tatcggcggt agcagccagt tccagaccac cgccataagc caggccgtgc
    27121 aacagggcga ttacgggctg tggcagttgt gccagagcat caaatgcctg atgaccgcgg
    27181 cggatccagt tgcgccacat atcgagtgca gaaagagagg tccagcgatg aatatccgcg
    27241 ccgacacaaa acgctttttc actggcactg gtcagcagta ctacgcggat ctccgaatca
    27301 gtttccaacg tgtggcaatg cgccagcagt tgttcgagca tctctggggt taatgcgttg
    27361 agtttcgccg ggcgattaat caccaaagtg gcaatgaaac cgttgcgctg gaggtcaatg
    27421 gtgccgttat tcatggtgac ttccttgttg aaaatagagg ggattcatta gtttgagatc
    27481 gtctgccaga cggagtgggg catcgctttg ggcgagaatg tcgcgttcag gatcaatacc
    27541 tggggcaatt tctgtgacca gtagcccgtc tggggttaat tccagaacgc agcgttcagt
    27601 aatgtactgt acttgttgcc cgagtcttat tgcgcgtttg ccggagaacg tcacgtgggc
    27661 gacgtcctgt accagttttt tggctttgcc ttctttaatg atacgcagct gaccctcttc
    27721 cagttgcagt tgggcaccgg cattgaaaaa gccagagaaa ataatgcgtt tcgcatgtga
    27781 ggtgatatca ataaatccac cgcatccggc agtgacatgt ggacgagcgg ggagatgtga
    27841 gacgttcact gagccatctg cgccgatttg taaaaacgac atcagagtga gatcaaaacc
    27901 accaccctgg aaataggtga actgctgggg agagggcaaa aatgcttctg cattagaggc
    27961 acaaccgaac tgaaattcca gcagtggaac tccgccaatc gcgccctgtt ccagcagcca
    28021 ggtgacgtca ccgtggcgac cttgttccag taaaatgcgt ggtacgttgg cagaaatacc
    28081 aaagccaata tttaccgcat ctccactttg tagttcttgc gcgactcgct gggcaataac
    28141 tcgcgccggg ccatgttcca tataacgaaa ggctgacagc ggacgactga tttcgccgga
    28201 aatggcaggt tcatattgcg tttgtgtcgt ttgtgtttgt tccggcgcaa tcacgatgta
    28261 atccaccagt acacccggaa tacgcacctc ttttggtttc agacttccgg cggcaacctg
    28321 tcgttttact tgcgcaatta tgatgccacc attattgcga acggcagtag cctgttccag
    28381 tggccccaga taagcccctt catgttcata agtcaggttg ccgcgttcat cggcagtggt
    28441 agcgcgaatg atcgccacct gcggcacgat actggggaaa aacagccagt cgtcgttagc
    28501 aaatcgaaca cgttcaacca gagattgttg cgccgctttt tcattcattg caccgccctg
    28561 caacagggga tccacatagg tatccatgcc tgtttgtgtc agcacgccag gacgatgagc
    28621 cgccgcttcc cggtgcatat caaataagat cccggaaggc agattccagg cggggatcgc
    28681 gttgtcattg atcatttgcc agattaacgg aggcgtcatt gatgatggac cggaggggta
    28741 ggagccagcg atcacttttg ccagtaagcc cggttgcgcc agatgatcga tgccttttac
    28801 gccatacata tcaccagcgg cgatagggtg gatggaggtg atgttttgcg gatgtccggc
    28861 acgttgaaag cgttcaccta ttgctgccag caccgcatcc ggacacccca ttccactgga
    28921 ggaggagacg gtgacaactg cgccatcaac aatcaaatct gcagcttccg gtgcagtgat
    28981 cgtgcgtaca gagcacataa taatttcctt gtttcgatat aaaaataatt aaaaatatac
    29041 atttaaaaca atatgataat tttcataaat taattggaac gatctaattt atgcgtaatt
    29101 tgtacgatta gggtgtaaaa aacacaacaa gggaagtgcg aatctgtgat cgaaacgacg
    29161 atctcctgcg atcccttgcg ttaacggatc gcatgagtaa aaggagatta tgataaagta
    29221 attgccttga tcttatgggg gtttggagca ggcatggcga agtcggatac aggaagaaag
    29281 cgggtaacat taaccgatgt tgcgcgtgcg gctggcgttt cgaaatcgac tgtatcgctg
    29341 gttctcaacg acagttcact tatcaaaaaa gagacgcaac aaaaagtcca gcaagccatt
    29401 gaacaattag gctatgtcta taaccgtttt gctgccaatc tgcgttcgca aaaatcgcta
    29461 actatcggcg tagtcattga cgatttgata aatcctttct tcgctgaatt tactatgggt
    29521 cttgagatga cgctggcgga gcacggtttt atcaccgtga tgtccaatac ctcccagcgt
    29581 agtgaccggc aaaaacaggt gcttgatacc ttgctggaac accacgtcgc gggcattgtc
    29641 ctctgtccag tgaacagtac ctcagaagcc gatttacagc gttatgccaa cagttccaca
    29701 cccttattaa tcacgatgcg ccctctggat tggcaacaat tgcccgtcga ttacgttggc
    29761 gtggacagcc acgcaggtgt acgggaagcg acggaatatc tcattcaaca agggcacaga
    29821 gatatcgtgt ttattggtgg tcttacgcac catatgcgtt atcagggata ccttgaggcg
    29881 atgaatcacc atggtttaca gccgtggagt actgatgctt tttcgctgcg tgctgaaccg
    29941 actcaggcca acggctacca gttgatgcaa cagctgttgg atatgccttc gccacccaca
    30001 gcggtgattt gttataacga tttaatggct tttggcgcgg agtcggcact aggcgaaaga
    30061 ggattatttg ccggggaaga tatttcgttg attggtaatg atggcgtggc ggcttgtgct
    30121 tacagtaacc cgccgttaac cacaattgcg gtagaaccat tggctctggg gaaacaggcg
    30181 gcgcagcaaa ttttacggcg tattgcgcaa ccagacgcac cgctcagcca ttacatctat
    30241 cgcccgaccc tgcaaattcg cgcttccacc ggaaagcggg ggcgttaaat gctgtagcga
    30301 gaaactgttt ctcgctatac tctcttgtcc cccattcaac agcaggtaac accattcgtt
    30361 atggcaggca atagaccttt caacaaacaa cagactgata accgcgaacg cgatccacaa
    30421 gttgccgggc tgaaagtgcc tccgcactcg atcgaagcgg agcagtcggt gttgggcggt
    30481 ttaatgctgg ataacgaacg ctgggatgat gtagccgagc gtgtggtggc agacgatttt
    30541 tacacccgcc cacaccgtca tatctttact gaaatggcgc gtttgcagga aagcggtagt
    30601 cctatcgatc tgattaccct tgcggaatcg ctggaacgcc aggggcaact cgatagcgtc
    30661 ggtggttttg cttatctggc agagctgtca aaaaatacgc caagtgcggc gaacatcagt
    30721 gcctatgcgg atatcgtgcg cgaacgtgcc gttgtccgtg agatgatctc cgttgcgaat
    30781 gagattgccg aagccggttt tgatccacaa gggcgtacca gtgaagatct gctggacctt
    30841 gctgaatccc gcgtcttcaa aattgccgaa agtcgtgcaa acaaagacga agggccgaag
    30901 aacatcgccg atgtgctcga cgcaaccgtg gcgcgtattg agcagttgtt tcagcagcca
    30961 cacgatggcg ttaccggggt aaacaccggt tatgacgatc tcaacaaaaa aaccgctggc
    31021 ttgcagccgt cggatttgat catcgttgcc gcgcgtccgt cgatgggtaa aacgacattt
    31081 gcgatgaacc tcgtcgaaaa cgcggcgatg ttgcaggata aaccggtact tatcttctcg
    31141 ctggagatgc catcagaaca gattatgatg cgttctctgg cgtcgctgtc gcgtgttgac
    31201 cagactaaaa tccgtaccgg gcagctcgat gatgaagatt gggcacgcat ttccggcacc
    31261 atgggtattt tgctcgaaaa acgcaatatc tatatcgatg attcctccgg cctgacgcca
    31321 acggaagtgc gttcccgcgc acgccgtatt gcccgtgaac acggcggcat cgggcttatc
    31381 atgatcgact acctgcaact gatgcgcgta ccggcgcttt ccgataaccg tacgctggaa
    31441 attgcagaaa tctcccgctc gctgaaagca ctggcgaaag aactgaacgt gccggtggtg
    31501 gcgctgtccc agttgaaccg ttctctggaa caacgtgccg acaaacgccc ggtcaactcc
    31561 gacctgcgtg aatctggctc tatcgagcag gatgcggact tgatcatgtt tatctatcgt
    31621 gatgaggtgt atcacgaaaa cagtgattta aaaggcatcg cggaaattat tatcggtaaa
    31681 caacgtaacg gcccaatcgg gacggtacgc ctgaccttta acggtcaatg gtcgcgcttc
    31741 gacaactatg cggggccgca gtacgacgac gaataataat tattttatga attaggtaat
    31801 taaagcaaac acttatcaag gaacacaaat gcaagcggca actgttgtga ttaaccgccg
    31861 cgctctgcga cacaacctgc aacgtcttcg tgaactggca cctgccagta aaatggttgc
    31921 ggtggtgaaa gcgaacgctt atggtcacgg tcttcttgag accgcgcgaa cgctccccga
    31981 tgctgacgcc tttggcgtag cccgtctcga agaagctctg cgactgcgtg cggggggaat
    32041 caccaaacct gtacttttac tcgaaggctt ttttgatgcc agagatctac cgacgatttc
    32101 tgcgcaacat tttcataccg ccgtgcataa cgaagaacag cttgctgcgc tggaagaggc
    32161 taacctggac gagccggtta ccgtctggat gaaactcgat accggtatgc accgtctggg
    32221 cgtaaggccg gaacaggctg aggcgtttta tcatcgtctg acccagtgca aaaacgttcg
    32281 tcagccggtg aatatcgtca gccattttgc gcgcgcggat gaaccaaaat gtggcgcaac
    32341 cgagaagcaa ctcgctatct ttaatacctt ttgcgaaggc aagcctggtc aacgttccat
    32401 tgccgcgtcg ggtggcattt tactctggcc acagtcgcat tttgactggg tgcgcccggg
    32461 catcattctt tacggcgtat ctccgctgga agatcgctcc accggtgccg attttggctg
    32521 tcagccagtg atgtcgctaa cctccagcct gattgccgtg cgtgagcata aagccggaga
    32581 gcctgtcggt tatggtggaa cctgggtaag cgaacgtgat actcgtcttg gcgtagtcgc
    32641 gatgggctat ggcgatggtt atccgcgcgc cgcgccgtcc ggtacgccag tgctggtgaa
    32701 cggtcgcgaa gtgccgattg tcgggcgcgt ggcgatggat atgatctgcg tagacttagg
    32761 tccacaggcg caggataaag ccggggcccc ggtcatttta tggggcgaag gtttgcccgt
    32821 agaacgtatc gctgaaatga cgaaggtaag tgcttacgaa cttattacgc gcctgacttc
    32881 aagagtcgcg atgaaatacg tggattaata ttcgtctcca gggagggaca atgtcttatt
    32941 cagaaatcgc cgcgtgtctg gcatacgcgg tttccgtctg gctggctgcc agaaacaatg
    33001 tgcatacatg gtggatcggc ataattggca gcatattgta cggctgggtt ttttggtccg
    33061 tgcaactcta tgccgacgtt acgctccagt tattcttcat cgtgaccagc atcactggct
    33121 ggatccactg gctgaaaggt cagggtggcg acatcttgcc ggtgcgccga acgcaagcca
    33181 gtcacttttt ccttttgttg ctctgtgctg tcgtcgtggc aggcggttac ggctttttac
    33241 tccacacctt taccaatgct tgggcaccct ggctggattc gttgattttg accttcagcg
    33301 ttctggcaca attcatgttg atgggaagac gtatcgaaaa ctggtacgtc tggttagcgg
    33361 tgaataccct ggcggtgcca ctgtatatga cgcgcggttt aaacctgacc gctggcttat
    33421 atttcctgtt ctggattaac gcctggtatg gtttgtatca atggcgcaaa gagttgcaaa
    33481 catcatgaag ccttttgcaa cgggtctggt ggttggtaaa ttcgcgcctt tgcattgtgg
    33541 tcatgaaaag ttgatcaata ccgcactggc gcaatgtgaa gaactgttca tcatcagtta
    33601 ttccgtgccg gaaatgcctg actgtgaacc tgaaaagcgc ctgacgtggc tgcaagtgcg
    33661 cttcccgcaa gcgacgtttt tggtactgac gccagagctt gttgcgcgtt ataacttacc
    33721 tgctatcccg cataacaatg ctgatgccga catccaccgt cattatgtgg cgacgctatg
    33781 cttgcagata ttacgttgcc gcccacacgc tgtatttact gcagaagact atggcgatgg
    33841 ctttgctaac gtgctggcgc ggcgttttgc ccaacccgtt gaacacgttc gaatggcgcg
    33901 cccagttggc gatgaagcgc cttcgggaac gcttattcgt tccgatgttc accgctatcg
    33961 ctacatgttg gcgaatgatg tttattacag tttcgttcgc cgtatctgtc tgcttggtgg
    34021 cgaatctacc ggtaaaagca cgctttcaaa agcgctggcg ggcgtgcttg atacggtgta
    34081 tgtcgctgaa tttggccgcg actattggga agaaaaaaac ggtatcttaa ctgcggatga
    34141 tttgttgcat atcgcctgcg aacaggtacg ccgggaacaa caagcagaag ctaatcacta
    34201 tcttatatgt gacacgtcgc cactcacgac cttattctat gcccttgatc aatatggtca
    34261 tgctccgcaa gaacttcacc aactggcgga gcgggaatac tctctggtag tgctttgcgg
    34321 cgcagaattt cccttcgtgc aggatggcac ccggcaagga gaggtatttc gcgcacggca
    34381 acaggtgtgg tatgaacagg aattgtcgcg caggaacatt ccttatcttt cggtttcggg
    34441 gccactgcaa gagcgagtgg agcaaattct tcgccaactt cccgactgac tttgaacatc
    34501 ctctcgatct tcgccttctt ccggtttatt gtggtttaac cacctgcccg taaacctgga
    34561 gaaccatcgc gtgtttcaaa aagttgacgc ctacgctggc gacccgattc ttacgcttat
    34621 ggagcgtttt aaagaagacc ctcgcagcga caaagtgaat ttaagtatcg gtctgtacta
    34681 caacgaagac ggaattattc cacaactgaa agccgtggcg gatgcggaag cgcgcctgaa
    34741 tgcgcagcct catggtgctt cgctttattt accgatggaa gggcttaaca gctatcgcca
    34801 tgccattgcg ccgctgctgt ttggtgcgga ccatccggta ctgcaacaac agcgcgtagc
    34861 aaccattcaa acccttggcg gctcaggggc attgaaagtg ggcgcagatt tcctgaaacg
    34921 ctacttcccg gaatcaagcg tctgggtcag cgatcctacc tgggaaaacc acgtagcaat
    34981 attcgccggg gctggattcg aagtaagtac ttacccctgg tatgacgaag cgactaacgg
    35041 cgtgcgcttt aatgacctgt tggcgacgct gaaaacatta cctgcccgca gtattgtgtt
    35101 gctgcatcca tgttgccaca acccaacggg tgccgatctc actaatgagc agtgggatgc
    35161 ggtgattgaa attctcaaag cccgtgagct tatcccattt cttgatattg cctatcaagg
    35221 atttggtgcc ggtatggaag aggatgccta cgccattcgc gccattgcca gcgctggatt
    35281 acccgctctg gtgagcaatt cgttctcgaa aattttctcc ctttacggcg agcgcgtcgg
    35341 cggactttct gttctgtgtg aagatgccga agccgcaggc cgcgtactgg ggcaattgaa
    35401 agcaactgtt cgccgcaact actccagccc gccgaatttt ggtgcgcagg tggtggctgc
    35461 ggtgctgaat gacgaggcat tgaaagccag ctggctggtg gaagtagaag agatgcgaac
    35521 tcgcattctg gcaatgcgtc aggaactggt gaaggtattg agcacagaga tgccagaacg
    35581 caatttcgat tatctgctta atcagcgcgg catgttcagt tataccggtt taagtgccgc
    35641 tcaggttgac caactacgtg aagaatttgg tgtctatctc atcgccagcg gtcgcatgtg
    35701 tgtcgccggg cttaacacgc aaaatgtgca tcgcgtggca aaggcgtttg ctgcggtgat
    35761 gtgattttaa tcaacaggcg gatctctccg cctgttcctg actccagcca ctccctacta
    35821 ttttgtccct tttttcgccc acttttacat catctctttt ctataagttt ttgaaaatta
    35881 gtgtttttaa ctgttggtac ggattgtgca gtaatgcagc tgtctatgac catcaggaga
    35941 aaaacatgga gaacatgacc tcgcccggca cgctgcttag tggagataac gcgacctggc
    36001 ttgaagagta ctaccagacc tggttgcgta cgccggaaca actcccggaa gactggcggc
    36061 gtttttttct ttcacctgaa ctgactgtcc aaagcgtatc cggtgataac aatatcagcg
    36121 gtgcgacctt aaaaaaacag gctgcggtaa tacaactgat caatgcctgg cgcacgcagg
    36181 ggcatctgcg cgcaaagctt gatccacttg gtttgaatcc cccggctgac gttccctccc
    36241 tccagcctgg tttttgggga ttaagcgaag aagacttgtt gcaggagttt agcgtcacct
    36301 ttggcgcaca caccacgcaa atgccactta agcaactgct taacctgctg gagcaagcct
    36361 gggccagtag ccaggcttat gaacttgctc atctggaaaa tcgtgaagaa atcaactggt
    36421 tgttatcacg gattgagagc agcaatgcgc cacaagctga tgcccaaacc tgtattgctc
    36481 gttttgaaaa actgatggcg gcagagacgt tagagcgtta tctgcatacc cgttatgttg
    36541 ggcagaaacg gttttctctg gaagggggcg aaagtgcaat cccggcgctc gatacgctga
    36601 caaaacgcct gcgtgcgcaa ggtgtggagg aaatggtcat tggcatggcg caccggggaa
    36661 gacttaatgt tctggttaat ctgttgaata aagacccggc acagcttttt gctgagtttg
    36721 aaggcaagca gacgatcggc agtggttcag gcgatgtgaa ataccacatg gggtattcca
    36781 gcaatctgga aacacctgcc ggttcgctgc atgtggcgct ggcgtataac ccctcacatc
    36841 tggagatcgt gaatccggtg gtgctgggcc aggtgcgagc caggcaggaa cgccgtggtg
    36901 aggatggtca ggcaaaagtg gtgggcgtac ttattcatgg ggattccgcg ttgggcggcc
    36961 tcggcgtcaa ccaaaccacg tttaacttat cgcagactca gggctacggc actggcggta
    37021 cgctacatct ggtgattaac aatcagattg gcttcaccac ttcccgcttg caggatatgc
    37081 gttcttcacg gtactgcacc gatattgcca aaatggtagc ggccccaatt atccacgtta
    37141 atggcgatga cgttgacgct gtttgccagg taatggaact ggcgtgcgaa tggcgagaca
    37201 ccttccggcg tgacatcatc atcgatattt gctgcttccg taagcacgga cacaacgaaa
    37261 gcgatgagcc acgtcttacc cagccacaaa tgtatcaggc agtggatgct caccctggta
    37321 cgctcgcccg ttatggtgaa tctcttgccc gccgcggcct gttaactcag gcgcaacaag
    37381 atgagatgac ggcacgctat cgcgactggc tggatagctg ccagaaacgt gaaccgcagc
    37441 ctctcaaacc tgcaattcac tcttttagcg ctaactggta tgggttgacc aaccctcact
    37501 ggagcgcccc ggtatctacg gcattgcctc ggcaaaagct ggcagcgtat ggtgaaatca
    37561 tttctacact gccacccgat gtggtcgcac atcctaccat taaacggcaa ctggcgttac
    37621 gccaggatat ggccgcaggt actcagccag tagactgggg aatggctgaa atgctggcct
    37681 atgcatcgct tgtggatgcg ggtgttggtg tgcgtctttc tggtgaagac tcagggcgtg
    37741 gcacgttcag tcatcgccat gcagtggtac atcatcaaac ggaagcccgt cgttatctgc
    37801 cgttacagca tatccgcgct ggtcaggcat ctttcgatgt ttatgattcg gtgcttaatg
    37861 aagaagcgct cttagccttt gaatatggct attcaacgtc tgcgcctcag caactggtta
    37921 tttgggaagc acagtttggt gactttgcca acggcgctca ggttgctatt gaccaattta
    37981 tctcgtctgg cgaaaccaag tgggatcgct atagcggttt aaccattctt ctgccgcatg
    38041 gctatgacgg acaagggccg gagcactctt ccgcacgtcc tgagcgctgg ctgcaactgt
    38101 gcgcagaaaa caacatgcag gtggtgatgc ccagtgagtc agcacaaatg ttccatttgt
    38161 tgcgcggtca ggcattacgc ccaatgcgca aaccgttagt gataatgatg agtaagcgtt
    38221 tacttcggtt taaaggcgcg atgagcgagc tttgtgaatt cactgatgac gcttataaac
    38281 cggtaatcac cgatccgcaa ttgcatcagt cccagaaagt taagcgcgtt attttgtgta
    38341 gcggccaggt ctattacgac gtactggaag cccgtaagca gcgtgagcat gaagacgagg
    38401 tagcgattgt tcgcctggag caactctacc cgttcccggt cgcagaactg aatgatgttc
    38461 tggcgagttg gccgaactgc tgcgaatgga tttggttgca ggaagagcca gaaaaccagg
    38521 gcgcgtggcg gcagattcgt catgagctgg cggcactgaa aattaacact ccttactggc
    38581 agtatgcagg ccgcccggca gcggcagcac cagcgacagg gtatgggcgt gtacataaac
    38641 aacaaatcga cgaatttctt gctgctgcgt ttgcagatat tcagccatga aaggcgcaca
    38701 aaaataataa ggagaacatt ttatgatcga aattactgtc cctgtattac cggaatctgt
    38761 cacggaaggc acgctgacaa cctggtgtaa acaagaaggc gagcacgtaa aacgcgatga
    38821 tgtgattgcc gagctggaaa ccgataaagt cattctggaa ataccggccc cgcacgatgg
    38881 cgtgttaagc aatattatcg tcagcgaagg tagcacggtc acgtccgcgc aactgttggc
    38941 gcatcttaag ccgcaagctg tcatagaaga aaccgtcaca ccagtcaccg aaaccctggc
    39001 gatgccttcc gcacggctgg aggcacagcg tagtggtgtc gaacttgctg acgttgcggg
    39061 gagcgggaga aatggacgta tcctgaaaga ggatgtgcag cgcgttactc ctgcaccagc
    39121 cattcagcct gaacgggtgg cggagatcgc gccagctaaa cccttgacac cgggtgctcg
    39181 tcaggaacgt cgtgagccga tgtcgcgctt acgtcagcga attgctgagc gtctgctggc
    39241 ttcccaacaa aataacgcca ttcttaccac attcaacgaa gtaaacatgc agagcgtgat
    39301 ggacttacgc gcccgctgga aagatcgttt tgccgagaag cacggcgtga agctgggctt
    39361 tatgtccttc tttgttaagg ccgttacccg ggcgctggag cgcttccctg tagtgaatgc
    39421 cagcgtcgat ggcaacgaga ttatctggcg tgattattgc gatatcggca ttgcagtgag
    39481 cagcaaccgc ggcctggtag tgcctgtgtt acgcaatgcg caatcactct ctttggtgga
    39541 aattgaacgg caaattgccg aatacgccac acaggcacgc aatggcaaat tgccgctgga
    39601 ggcgttacag ggcggcacgt tctctatcac caacggcggt acttttggtt cgatgatgtc
    39661 aacgccaatc attaacccgc cgcagtcggc cattcttggg atgcatgcca tcacgccgcg
    39721 cccggtcgca gaaaacggtc aggttgttat tcgtcccatg atgtaccttg ctctcagcta
    39781 tgaccatcgc attatcgatg gtcaggaagc cgtgcataca ttggtggcaa tacgtgagct
    39841 actggaatca ccggaacaac tgttgctgga tctttaagga gggcgccgat gagtacaatt
    39901 tttgatgtgg cagttatggg gggggggcca ggtggttacg tagcggcact gcgggctgcg
    39961 cagaatgggc tttccgtagt atgtattgat gatggtgtta atgcacaggg cgaaccttcg
    40021 ccgggcggta cgtgtctcaa tgtcggctgt attccgtcaa aatcgttgct gcaatcttcc
    40081 gaactgtacg cgcaagtgca gcatgaggcg agcattcatg gcgttaatgt tgacggcgta
    40141 tctttcaatg cagctgcgat gattcaacgt aaagacgcca tagtaagccg cctgacaatg
    40201 ggcatcagct tgctgtttaa gaaaaataaa gtgaagcacc tgtgcggcct cgcaacgtta
    40261 gaatgtgctc aggatgagat ttggcaatta cgtgtaaacg atcaacacct tcacgcccgt
    40321 aatgtagtga ttgcaacagg ttctcagccg cgtcagctgc ctggcgttac cattgataat
    40381 caacagatcc tcgacaatcg tggcgccctg gcattgagcg aagtgccgcc gcgtctcggt
    40441 gtgatcggcg ctggcgtgat tggccttgaa ctggggtctg tgtggaatcg ggttggttca
    40501 gacgtcacgt tgctggagat ggcgccaacg ttcttgcctg cactggaagc tcgcctgtcg
    40561 aacgaagtcc gtaaagcaat gattgccagt gggatgaaaa tgcaactggc agtagagatt
    40621 gaggctattg aacaacggga tgacggtgtg catgtgcgct ggcggcaggg tgagaagcga
    40681 gaagaaagcc gcttcgataa attaattctt gccattggac gtgtaccgcg actttctggt
    40741 gtcgatctcg tgcaactcgg tcttgaagcc gataaccgtg gcggtattgc cgtcgataac
    40801 ttatgccgta ccgggaaagc cgggctgtgg gcaattggtg atgtcgtgcg agggccgatg
    40861 ctggcgcata aagcgatggc tgaaggtgta gtggtggctg atcaaattgc cggactggtg
    40921 gtagagccga ttaattttgc gctgatccct tcggtgattt acacccaacc ggaagttgcg
    40981 tgggtagggg aaaacgaggc ctcactgaaa gccgctggca gagtctttaa caaaggaaat
    41041 tctctgtttg ccggtaacgg tcgcgcctta gcattaggcc aggaaggtgg gcgttgcacg
    41101 ttatacagtg ataaacacac tgaccgcgta cttggcggag cgattgttgg cccgcaggca
    41161 tcggagctga ttaatgaaat tgcgctggcg atgactttta gcgcctctgg cgaggatatt
    41221 gcctgtgcga tccatgcgca tccgacatta agcgaagtca tccacgaagc agcaatggcc
    41281 ttgaataata aagcattaca cggataacac acaccactga gggaatatat gaatttacat
    41341 gagtatcagg ccaaatcgtt actggctggc atggggatgc cgtgtccaaa agagatagct
    41401 atccaacaga tttcgcaact ggcagatgcc tggcaacata ttgcttgccc gagtaaaggc
    41461 gcggtactta aagcgcaggt acatgctggt gggcgcggta aagctggcgg cgtaaaagtg
    41521 cttaagcagc tgccggaagc acaggctttt gtacagcaaa tgttgggatc gcaactggtg
    41581 acttatcaga ccgggccaga aggacagtat gtcagcagta ttttactgtg cgaaaacatt
    41641 tatccggtac gccaggaact ctattttggc atggtggtgg atcgtgaaag ccagcgggtc
    41701 acgtttattg tcagcccgga aggtggtgtg gaaattgaaa aagtcgccca tgagacaccg
    41761 gagaaaatca gcagtgtcag cattgatcca ctgacaggcg tgcagccttg ccatatccgc
    41821 gaaatgtttg ctgttctgca actggaacac ggactatttg ctgcctttag tcgcctggtt
    41881 aatcaggcgt ggaaagcctt taacgaactg gattttgccc tgctggaaat taaccctctg
    41941 gtgttgcggg aaacgggcga atttatgtgt gcagacgcga aagtatcgct ggatgataac
    42001 gcgctgtatc gtcacccgga actccaggtg ctacgtgatg aaacccagga agatccacgc
    42061 gaaagccagg cagcgaagct tgatcttaat tatgtctcgc tggacggaaa tatcggctgc
    42121 atggtcaatg gtgcagggct ggctatggca accatggaca tcatcaagct atacggtgaa
    42181 caacccgcaa acttcctgga tgttggcggt ggcgcaaccc aggagcgcgt cagtgaagcc
    42241 tttcggctga ttgtttccga cagcaaagtg aaagccattc tggttaatat ttttggtggg
    42301 attgtccgtt gcgacatgat cgccagagcc attattcatg ctctgaatga ggccagcatc
    42361 accctgcctg tcgtggtgcg tctctccggt aataacgccg ccgaagggca gcggttactg
    42421 gcagaaagtg gtctgacggt ggaagccgtc gattctctgg atgatgccgc gaaacgcatc
    42481 attgcgttac tgaattaaca ggaggttaag atgagcgttt tgatcaacaa acacacgcgg
    42541 gtactggtgc agggcattac cggcaaaaac ggcacatttc atacagagca ggctattgcg
    42601 tatggcacgc agattgtggg tggagtgacg cctggtaagg gcgggcaacg gcatctggat
    42661 cgcccggttt ttgattcaat gaaagatgcg atgcgacaaa ctgaggccga tgccagcgtg
    42721 atttatgtgc ctgcaccgtt tgtgctggat tctgttgttg aggctattga agctggcgtc
    42781 aaattggttg tggtgatcac tgaaggtgta ccgacactgg atatggtgaa agttcgtcgg
    42841 ctgcttgact gccacccgga tgtgcggctg attgggccaa actgcccagg agttatcacg
    42901 ccgggtgagt gcaaaatcgg gattatgcct ggtgaaatcc accgcccagg gcgtattggg
    42961 attgtttccc gctccggtac attaacctac gaagctgtag cgcaaaccac ggcgctggga
    43021 cttgggcaat ccacctgtat tggtattggc ggcgatccgg ttccggggac taactttatt
    43081 gatgcgctgc gtttattcga aaatgatccg caaacagacg cggtaattat gatcggtgaa
    43141 attggtggta atgcggaaga acgggccgcg gaatttattc gccatgatat gaataaaccg
    43201 gtcgtaggtt atattgccgg tgttactgca ccaaaaggaa aacgcatggg acacgccgga
    43261 gccattattt ctggcggtag cggcagtgca gaggataaat tccgtgcgtt cgataaagca
    43321 ggcatggcat ggacaagaaa cccggcgttg cttggcgaaa cgttatggaa tgttattaag
    43381 taatccataa atgaatatca agggagcata tcgctccctt tttttatctg tgtggtaaga
    43441 gaatcacctt ttatttactg tgcggaaaac cgcgcacaaa ataaaaagaa taaataataa
    43501 aatcattaaa taacaaagca ttattaaaaa attaaagatg gcatagctcc tgcaatagcc
    43561 aggcaggttt tttatttttc acaatgaggt gaatatgtca tcaatatcac atggcgcacc
    43621 acaaaagcgt cgaattatcc ctaatcccgg cctgtggttg gcgatcattg ccggaattat
    43681 tattactctt ctgcctctgg gcgatacctt gcccgtcgcc ggacaaaata tgatcgccat
    43741 tctggtgttt gccattattg tctggatcag cgaagcgatg gattacaccg ccagtgcaat
    43801 tgttatttcc gcactgatta tctttatggt tggttttgcc ccggatatga atcacccgga
    43861 cacgatcctt ggcaccgcga aagcgctgaa aatgactctg tcgggttttt ctaattctgc
    43921 tctggcgctg gtggcagcag caatgtttat cgcggcggca atgaccatta ccgggctgga
    43981 taaacgtatt gcgctgttta ctatgtcgaa aataggtgcc agtagccgca gcattattat
    44041 cggtgccatt gtggtgacca tcgtcctgag cctggtcgta cccagtgcca ctgcccgtac
    44101 ggcttgcgtg gtgccgatta tgatgggggt cattgcggca tttaaggtgg ataaacattc
    44161 acgtttagcg gcgtcaatga tgattgttat cgcccaggcg accagtatct ggaacgttgg
    44221 tattcaaact tcgtcggcgc aaaacctgct ttctatcggt tttatcaata aaactttcgg
    44281 cgccgggcat tctgtcagct ggcttgactg gctgttagcg ggcgcgccct ggagcctcac
    44341 catgtcggtg atcctctatt tcctcgcacg taaattgttg ccgccagaaa cggaagctgt
    44401 tgaagggggg agcgaggcca ttaaaaaagc actcgcagag ttagggccaa ccaccggtaa
    44461 agaaaaacgc ttgatcggta tttcgctgtt gttactgctc ttttggtcta ctggcggaaa
    44521 attacacagt attgatacca cctctgtcac ccttgccgga ctggcgatta tgttgctgcc
    44581 aggcatcggt gtaatgagct ggaaagaggt cgaaaaacgt gtgcagtggg gcacgttgct
    44641 gatgtttggt attggtatca gcctggggtc cacgttgctt gatacacagg cagcttcatg
    44701 gatggcgaac tatgtggtga aaggttttgg tcttgacggt ttaccatcac ttgccatctt
    44761 cgcgattctc gccgctttct tgataatcat tcacctgggg tttgccagtg ccactgcgct
    44821 aactgccgca ttgctgccca tcctgattag cctgttaagc agtctgccgc cagaactcgg
    44881 cgttaacccg gtcggcatga ccattctgct cgccttcagt gtcagttttg gcttcatcct
    44941 gccgattaac gcgccacaaa atatggtgtg tatgggtacg gataccttca cgccacgcca
    45001 gtttacccgt gtgggactgt acctgacggt aatcggctac ctgttgttgc tactgtttgc
    45061 cgccacctgg tggaaaattt taggtctaat gtgaggaaac caacgatgtc attacaaatt
    45121 gctgttgaaa aagtgcgttg gttagctgcc gggctgctgg aacttaatgg ctgtgatgcc
    45181 gatatcgctc aggatgtggc ggaacatatg attgaagcgg aacgttatgg ctttgccagc
    45241 cacggcgtca cgctgctacc gaaatatctg gaaaatatcg ctcgtggcga tgtaaccgcg
    45301 aatgcccgcc cggaatgctt aacaagtgaa ggtaatttac agcgttttca tgcccacaat
    45361 ggctttggtc aacacgccgg aaaagtggcg gtaaatgctg ccatcgaaca aacaaaacac
    45421 cgcggttttt gcctgttaac gttgtgccat gcgcatcatt tagggcgtat ggggcattac
    45481 gggcaaatgg ttgctgatca aggcctggcg atgctggcca tgagtaacgt caccgggcgt
    45541 cctgcactgg tcgccccgtg gggcggtgcg gaaccgcgta tgaccactaa ccctttctgc
    45601 tttgcctggc cgttcagtga tgggcgtccg ccgattctgg ttgattttgc caccagtagc
    45661 atggcgctaa ataaagcacg ggtaatgtcg tccaccggga agcaggccgc gccgggacaa
    45721 ttgattgatg cacaggggaa tccaagcaat gatcctgggg tgttattcag caatcctcca
    45781 ggggcgttac tgccatttgg tgagcataaa ggatttggcc tggcactgat gattgaaatg
    45841 atggcgggga tcttatctgg tggtgacacg atcgccgaag atcatcagac ggatggatct
    45901 gcgcataatc atctttttgc gttgattatc gatcctgatc aattcaccga tctggcaggg
    45961 gagaaagggc agttctttgc ggattatctg ttagctacgc agcctcaacc tggcggcaat
    46021 ccggtgattt accccggtat gccagaagct gccaaccggg aacgcaatgc gaagatgatt
    46081 acgatcccgg tatcattctg gtcctgggta gttgaacatt acgcccgcaa aggtatcgat
    46141 ttggggttac atcctcagga atcagcatta gctggatgat tctggtcgat aaacttgcgg
    46201 ttgaatctga tgtttgttga gtttgtcata taaagtcttg cgcggcagct gtaatagccg
    46261 cgctgtcaaa ctgacctggc cttccgtttg tcgcagcata tcttcgatta actttttctc
    46321 gaaagcatca atgcaggcgg taagaccact ctcttcttgc tgagtcattg gcactggctg
    46381 gtggtgggtc agtaaaccga gaacaaaacg ctctgcattg tgtttaagtt cacgtacatt
    46441 gccaggccaa ctttgtgact gcaaccaggc cagtaacatg ggagaaatat caggcagagg
    46501 acgattatat ttttgtgccg cctgactggc gaaccagtaa aacagttcag ggatatcttc
    46561 tcgtcgctgg cgtagaggtg gaatattcag gctaaccaca ttcagacgat aatagagatc
    46621 gagacgaaac agatgttctt cgctgcgacg cagtaaatct tccttggtcg ctgcaataac
    46681 acggcaattc accggaatta attgattggc acctaatcgt tcaatggttc tttcctgcaa
    46741 tacacgtagc agttttacct gcattcctga tggcattccc tctatttcat cgagaaataa
    46801 cgtaccacca tttgcatgtt caatttttcc aatacgcttt ttaaccgcac cggtaaatgc
    46861 gcccgcctca tgaccaaata tttcgctttc aaacaacgtt tctggtaagc ctgcacagtt
    46921 taaggcaaca aactgcccct gacggcgggt actccagtga tgcagcattc tggcgacgac
    46981 ttctttacca caacctgttt caccataaat aaggacatcg gcaccggtat ctgcgacatt
    47041 aaggatcatt ttacgcagtt gctgcatctg cggactacga ccaatcagca ccgggccatt
    47101 ttcctgttgc agattcgcca gtaattgctg attttctaaa accaatcgcc gtttttctac
    47161 cgctctggca ataatactca ataatttatc tgagctactt ggtttctcaa tgaaatcgaa
    47221 tgcaccatta cgcatggcat ccaccgccat ttccacgtca ccgtgtccgg taattaaaat
    47281 aaccggaatt ttgctatcca tttcgttgat gtaactgagg agctctagtc ctgatattcc
    47341 aggtaacctg acatcggtca gtataataat gttggcctga ctttgaataa ggggaatact
    47401 gtgttctgca tcgcaacagg aaataacgcg ataaccagcc agcgtgagcg tttgttcaca
    47461 ggcaaaacgt a
//
LOCUS       DAFGPF010000025        46381 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFGPF010000025 DAFGPF010000000
VERSION     DAFGPF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46381
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.025"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..785
                     /gene="pdeL"
                     /locus_tag="LSX49_001639"
     CDS             <1..785
                     /gene="pdeL"
                     /locus_tag="LSX49_001639"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding transcriptional activator/c-di-GMP
                     phosphodiesterase PdeL"
                     /protein_id="HBL7168065.1"
                     /translation="HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRW
                     EHPQTGMIPPDQFIPLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAG
                     CFLAAGFEKECLNLVKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALD
                     DFGTGYATYRYLQAFPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEG
                     VETQEQADLMIGKGVHFLQGYLYSPPVPGNKFISEWVMKAGG"
     gene            complement(827..1759)
                     /locus_tag="LSX49_001640"
     CDS             complement(827..1759)
                     /locus_tag="LSX49_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7168066.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFHAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMAQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHRES"
     gene            complement(1851..2348)
                     /locus_tag="LSX49_001641"
     CDS             complement(1851..2348)
                     /locus_tag="LSX49_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBL7168067.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALAAGWLASVSGISGFWASVITTVPFSAVV
                     VWQGRFGLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATT
                     KRDGY"
     gene            2606..3211
                     /locus_tag="LSX49_001642"
     CDS             2606..3211
                     /locus_tag="LSX49_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HBL7168068.1"
                     /translation="MTIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLANTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLKLARERGFEEIAQLLIAAGA"
     gene            3251..4114
                     /locus_tag="LSX49_001643"
     CDS             3251..4114
                     /locus_tag="LSX49_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HBL7168069.1"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFNGLFRHDDKVQFDDQGITIGQHHHIEMSHCQRWLSPTLQMTAV
                     NFHLIAWQQWYDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLVLILFISGHPAEKYKEEFYLGLQRGRNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     gene            4104..5651
                     /gene="fdrA"
                     /locus_tag="LSX49_001644"
     CDS             4104..5651
                     /gene="fdrA"
                     /locus_tag="LSX49_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HBL7168070.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGVDNEQLLAEIEELFNTKAQSGSHEARYG
                     TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAISMLENDPQTEIIVLISKPPAPAVARKVLERARACRK
                     PVVACFLGRGETPVDEQGLQFARGSKEAALKAVMLSGVKQEHLDLHTLDQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETLFAVMEKHGDVYSNIQPDPEFRLQDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            5651..7069
                     /locus_tag="LSX49_001645"
     CDS             5651..7069
                     /locus_tag="LSX49_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HBL7168071.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKITAANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
                     PPVTWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     gene            7222..8172
                     /locus_tag="LSX49_001646"
     CDS             7222..8172
                     /locus_tag="LSX49_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HBL7168072.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSESQRDELQKANPDWRFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQDGKEVIITTPECLPAALRGETGTHIIKT"
     gene            8182..9564
                     /locus_tag="LSX49_001647"
     CDS             8182..9564
                     /locus_tag="LSX49_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBL7168073.1"
                     /translation="MKENNSRREFLSQSGKMVTAAALFGTSVPLAHAGVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKQHPDAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQTGFECEIVAFP
                     QHGLLLSKSESLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELAHRMAAQRISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     gene            9941..10990
                     /gene="yahK"
                     /locus_tag="LSX49_001648"
     CDS             9941..10990
                     /gene="yahK"
                     /locus_tag="LSX49_001648"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HBL7168074.1"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPHDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSESKREAAKALG
                     ADEVVNSRNADEMVAHVKSFDFILNTVAAPHNLDDFTTLLKRDGTITLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            11613..11857
                     /locus_tag="LSX49_001649"
                     /pseudo
     CDS             11613..11857
                     /locus_tag="LSX49_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11874..12545)
                     /locus_tag="LSX49_001650"
     CDS             complement(11874..12545)
                     /locus_tag="LSX49_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HBL7168075.1"
                     /translation="MMKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYIFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLTSIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            12692..12967
                     /locus_tag="LSX49_001651"
     CDS             12692..12967
                     /locus_tag="LSX49_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBL7168076.1"
                     /translation="MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVASQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            complement(13068..14654)
                     /gene="prpR"
                     /locus_tag="LSX49_001652"
     CDS             complement(13068..14654)
                     /gene="prpR"
                     /locus_tag="LSX49_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HBL7168077.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFSRHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGQFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKMSLAALSVPFSAALRQGLETCQILLLHYDWPGNIRE
                     LRNMMERLALFLSVESTPDLTPQFLQLLLPELARESAKTPIPGLLTAQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            14893..15783
                     /gene="prpB"
                     /locus_tag="LSX49_001653"
     CDS             14893..15783
                     /gene="prpB"
                     /locus_tag="LSX49_001653"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HBL7168078.1"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNILRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDDLFARGQVK"
     gene            15943..17112
                     /gene="prpC"
                     /locus_tag="LSX49_001654"
     CDS             15943..17112
                     /gene="prpC"
                     /locus_tag="LSX49_001654"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HBL7168079.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEIFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ"
     gene            17146..18597
                     /gene="prpD"
                     /locus_tag="LSX49_001655"
     CDS             17146..18597
                     /gene="prpD"
                     /locus_tag="LSX49_001655"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HBL7168080.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSRVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPVFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI"
     gene            18637..20523
                     /gene="prpE"
                     /locus_tag="LSX49_001656"
     CDS             18637..20523
                     /gene="prpE"
                     /locus_tag="LSX49_001656"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HBL7168081.1"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDREVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            20848..22107
                     /gene="codB"
                     /locus_tag="LSX49_001657"
     CDS             20848..22107
                     /gene="codB"
                     /locus_tag="LSX49_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBL7168082.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     gene            22097..23380
                     /gene="codA"
                     /locus_tag="LSX49_001658"
     CDS             22097..23380
                     /gene="codA"
                     /locus_tag="LSX49_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="HBL7168083.1"
                     /translation="MSNNALQTIINARLPGKEGLWQIHFHDGKISAIDAQSGVMPVTE
                     NSLDAEQGLVLPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTKPAQTTVYLEQPEAIDYKR"
     gene            complement(23501..24112)
                     /gene="lacA"
                     /locus_tag="LSX49_001659"
     CDS             complement(23501..24112)
                     /gene="lacA"
                     /locus_tag="LSX49_001659"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HBL7168084.1"
                     /translation="MNMSMTERIKAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEF
                     EKRESLIKEMFATVGENAWVDPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGCHVVINPGITIGDNSVIGA
                     GSVVTKDIPPNVVAAGVPCRVIREINDRDKQYYFKDFKVESSV"
     gene            complement(24178..25431)
                     /gene="lacY"
                     /locus_tag="LSX49_001660"
     CDS             complement(24178..25431)
                     /gene="lacY"
                     /locus_tag="LSX49_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HBL7168085.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSHFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLVAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     gene            complement(25483..28557)
                     /gene="lacZ"
                     /locus_tag="LSX49_001661"
     CDS             complement(25483..28557)
                     /gene="lacZ"
                     /locus_tag="LSX49_001661"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HBL7168086.1"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPDADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPAENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFQVTTRFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPELWSAEIPNLYRAVVKLHTADGTLIEAEACDVGFL
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTSATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQYFQFRLSGRTIEVTSEYLFRHSDNEFLHWMVALDGKPLASGEVPLDVGPQGKQLIE
                     LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPSASHAIPQ
                     LTTSETDFCIELGNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGHGEMVVSVGVEVASDTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFNRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            complement(28680..29762)
                     /gene="lacI"
                     /locus_tag="LSX49_001662"
     CDS             complement(28680..29762)
                     /gene="lacI"
                     /locus_tag="LSX49_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor LacI"
                     /protein_id="HBL7168087.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQACHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACANVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPITEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLPPNT
                     QTASPRALADSLMQLARQVSRLESGQ"
     gene            complement(29839..30672)
                     /gene="mhpR"
                     /locus_tag="LSX49_001663"
     CDS             complement(29839..30672)
                     /gene="mhpR"
                     /locus_tag="LSX49_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator MhpR"
                     /protein_id="HBL7168088.1"
                     /translation="MQNNEQTEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLH
                     RTTVRRLLETLLEEGYVRRSTSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLR
                     EVVWPTDVSTLDVDAMVVRETTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQE
                     RKELIEMLASRPGDDYQLAREPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLR
                     SEQRVIGCLNLVYMASAMTIEQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHL
                     R"
     gene            30863..32527
                     /locus_tag="LSX49_001664"
     CDS             30863..32527
                     /locus_tag="LSX49_001664"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HBL7168089.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGLSRFPNVRCLFSRELEAFSQQDDEVTLHLKTEEG
                     QRETVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     gene            32529..33473
                     /gene="mhpB"
                     /locus_tag="LSX49_001665"
     CDS             32529..33473
                     /gene="mhpB"
                     /locus_tag="LSX49_001665"
                     /EC_number="1.13.11.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxyethylcatechol 2,3-dioxygenase"
                     /protein_id="HBL7168090.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            33491..34357
                     /gene="mhpC"
                     /locus_tag="LSX49_001666"
     CDS             33491..34357
                     /gene="mhpC"
                     /locus_tag="LSX49_001666"
                     /EC_number="3.7.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /protein_id="HBL7168091.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARP"
     gene            34367..35176
                     /gene="mhpD"
                     /locus_tag="LSX49_001667"
     CDS             34367..35176
                     /gene="mhpD"
                     /locus_tag="LSX49_001667"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HBL7168092.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQHDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNETIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            35173..36123
                     /gene="mhpF"
                     /locus_tag="LSX49_001668"
     CDS             35173..36123
                     /gene="mhpF"
                     /locus_tag="LSX49_001668"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="HBL7168093.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEENVAQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            36120..37133
                     /gene="dmpG"
                     /locus_tag="LSX49_001669"
     CDS             36120..37133
                     /gene="dmpG"
                     /locus_tag="LSX49_001669"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HBL7168094.1"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAVLKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGGDLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     gene            37309..38520
                     /gene="mhpT"
                     /locus_tag="LSX49_001670"
     CDS             37309..38520
                     /gene="mhpT"
                     /locus_tag="LSX49_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter MhpT"
                     /protein_id="HBL7168095.1"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESTVFAGEKQAAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNSMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRMQPCADA"
     gene            38622..39161
                     /locus_tag="LSX49_001671"
     CDS             38622..39161
                     /locus_tag="LSX49_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HBL7168096.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQTQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(39286..40119)
                     /gene="fghA"
                     /locus_tag="LSX49_001672"
     CDS             complement(39286..40119)
                     /gene="fghA"
                     /locus_tag="LSX49_001672"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HBL7168097.1"
                     /translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAENEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPNLVMHHFPATARKSIAGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(40212..41321)
                     /gene="frmA"
                     /locus_tag="LSX49_001673"
     CDS             complement(40212..41321)
                     /gene="frmA"
                     /locus_tag="LSX49_001673"
                     /EC_number="1.1.1.284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="HBL7168098.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFELARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            complement(41356..41631)
                     /gene="frmR"
                     /locus_tag="LSX49_001674"
     CDS             complement(41356..41631)
                     /gene="frmR"
                     /locus_tag="LSX49_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HBL7168099.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            41937..42899
                     /gene="tauA"
                     /locus_tag="LSX49_001675"
     CDS             41937..42899
                     /gene="tauA"
                     /locus_tag="LSX49_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7168100.1"
                     /translation="MAISSRNTFLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVATSQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDAWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
     gene            42912..43679
                     /gene="tauB"
                     /locus_tag="LSX49_001676"
     CDS             42912..43679
                     /gene="tauB"
                     /locus_tag="LSX49_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding subunit"
                     /protein_id="HBL7168101.1"
                     /translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKGIQGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEK
                     MQRLEIAHQMVKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     gene            43676..44503
                     /gene="tauC"
                     /locus_tag="LSX49_001677"
     CDS             43676..44503
                     /gene="tauC"
                     /locus_tag="LSX49_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HBL7168102.1"
                     /translation="MSVLINEILHSHRLKWRWPLSRQVTLSIGTLAVLLTVWWAVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRILLALLAAVLIGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            44500..45351
                     /gene="tauD"
                     /locus_tag="LSX49_001678"
     CDS             44500..45351
                     /gene="tauD"
                     /locus_tag="LSX49_001678"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HBL7168103.1"
                     /translation="MSERLSITPLGPYIGAQITGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIQTPPAGAILAAKELPSTGGDTLWASGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEAEHQRWREAVAKNPPLLHPVVRTHPVTGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     IPFYRAG"
     gene            complement(45391..46365)
                     /gene="hemB"
                     /locus_tag="LSX49_001679"
     CDS             complement(45391..46365)
                     /gene="hemB"
                     /locus_tag="LSX49_001679"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBL7168104.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
BASE COUNT        10917 a        11963 c        12799 g        10702 t
ORIGIN      
        1 atcactatca ccatatcgtc acgcctgaag ccatcagtct ggcgttggaa aaccacgagt
       61 ttaaaccgtg gatccaaccg gttttctgcg cgcagactgg ggtactgacg ggctgtgaag
      121 tgcttgtccg ctgggaacat ccacaaacgg gaatgatccc accggatcag tttattcctc
      181 tggcggagtc atccggtctt attgtcataa tgactcgcca gctgatgaaa cagactgcgg
      241 atattctgat gccggtaaaa catttgctgc cggacaattt ccatattggt atcaacgtct
      301 cggcgggctg ttttttggct gcgggatttg aaaaagagtg tctgaacctg gttaagaaat
      361 taggtaacga taaaatcaag ctggttcttg agttgactga acgtaatcct attccggtaa
      421 cgccagaagc cagagcgata tttgacagcc ttcatcagca caatattact tttgcgctgg
      481 atgactttgg tacgggttat gcgacctatc gttacttgca ggcgttcccg gtcgatttta
      541 ttaaaattga caagtcgttt gtgcaaatgg cgagtgtcga cgaaatctcc ggtcatattg
      601 tggacaatat tgtcgaactg gcgcgtaagc ctggtttgag tatcgtggcg gaaggggtag
      661 aaacccagga gcaggcggat ttaatgatcg gcaaaggcgt tcacttttta cagggctatt
      721 tgtactctcc gccagtaccg ggtaataaat ttatctctga atgggtaatg aaagcaggtg
      781 gttgatgtaa accgctattc acagcgcatc gggaggttgg cagcgattaa ctctcccgat
      841 gcagtaaatc ctgatagatc cccgttaata tgccatttgg cgcaaattgt tttttaatcc
      901 actgcgtcac ctgaccggtg gcagagtgct gggttgcgag taacatgcgt gaatcctggc
      961 gcgggttatg gatttgtcgg gtaaccagca aggattgcgc catcgcctca cggaccatgt
     1021 aatccggcaa aaaaccaatt ccttcaccta aaatctggca ctgacatttg gtgttgaaat
     1081 cgggcaccag aatcgattcc tgcccatgca gcaaccagcc tactttttta ttaatcgtat
     1141 gcgcggtgtc ctccaccatg atattagggt agagacgcag ctggctttcg gcgatcggct
     1201 ccggcacaaa ggctaatgga tgatccggag cgatggcaaa agcccagcga atcgcgccaa
     1261 tctccgtgta atcaatgccg ccaccgtcca gcagcgtgtc gggtgcgccg atagcgatat
     1321 ttgcctgatt attaataatc gcatcccaga cgccgttata cacttcggtg gtgacggtaa
     1381 tctggcaggt aggaaactgc tttttcagca cctgtaataa gcgtgcggtg tgtttgggcg
     1441 tataaagcag ctgattaata caaatgcgca cacgcgcttc tatgccctgc gaaatagtat
     1501 cgatactgcg tttaatggcg tgaaaatcat tcagcaggtc ggtagctttg cggaaaaaat
     1561 aacgcccgga ctccgttaac tcaatgctgc gggtactgcg agtgaacagc accacatcca
     1621 gccctgtttc cattcgcttg atggtgtagc taatggcgga agtggttaaa cccaactctt
     1681 ctgcggcttt actgaagctg ccaaaacgtg cagcggtagt aaatgccaac agattctctt
     1741 cggtaaaaat tgagttcatt aaaccattcc cgccattatc gaatatgaat ttctccagcc
     1801 atgactgtag aggtatcggt taaagataga taatcatttt tgaataactt ttaatacccg
     1861 tcgcgtttag tcgtcgcttc gcttaatttt tgtcctccat attctgaaat tatccccacg
     1921 cagttacccg ccagaaaacc cagtaatgtc accgtccagt tcatcccgct ggcaaaaaat
     1981 agcgtcatgc cgagaaagcc tccgggaata aaagacaata aaccgaaacg tccttgccag
     2041 accactaccg ctgagaaagg cacggtagta atcacgctcg cccagaaccc agaaatccca
     2101 ctcaccgagg ccagccaacc ggcagccagc gcggcgaaaa atgcccacac catcccggaa
     2161 taattaaccg ccagacttct gataaacccc gatttaccgc cgcctgcggc ataaaaactg
     2221 caaaaggcga cgaagccaat ggttcctaat aattcccatc cctgagagag cccgacatgt
     2281 gaagacacta actgccaaag ccctgcacaa ataccgacgg tgacacccgt tgccgtgagt
     2341 ccgttcatct tgttcccctc tggttagaca tggacaaaag ctactcttac atgtgcagac
     2401 tatagagaaa taaaacctga ttgagtgaaa gggtatcggg tcaaagaaac aaatattgca
     2461 ctaccgcaca ctgcgaaaag attgttgaac atcattcaac aaaaaggcga aatacggcga
     2521 attaaattta agcgggttct tttatcagat tatcgttgct attctcaatt catcgaaaac
     2581 agccacaaaa accaggggaa tgtgaatgac tataaaaaat ctacctgccg actatttatt
     2641 ggctgcgcaa cagggtgata tcgataaagt aaaaacctgc cttgcgctgg gtgtcgatat
     2701 taatacctgc gatcgtcagg ggaaaacggc aattacgctg gcaagtttat atcagcaata
     2761 tgcttgcgtt caggcattaa ttgatgccgg agcggatatt aataagcaag atcatacctg
     2821 tttaaatcct tttttaatta gctgtctgaa cgatgattta acgctactac gaattatttt
     2881 accggctaaa cccgatctta attgcgtaac ccgttttggc ggtgtcggcc tgacgcctgc
     2941 ctgtgaaaaa ggccatttaa gtattgtaaa agagcttttg gcaaatacgg agattaacgt
     3001 taaccagact aaccatgttg gctggacacc gttgctggaa gcgattgtgc ttaatgatgg
     3061 tgggattaaa cagcaggcga ttgtccagtt attgctggaa cacggtgcca gcccgcatct
     3121 gaccgataaa tatggcaaaa cgccgctgaa actggcgcgg gaacggggct ttgaagagat
     3181 tgcgcagttg ctgatcgccg caggtgcata aaccgggagg cttgttatca acacaccaga
     3241 aaaacggtgt gtgtgggcgc taactgcgga tgctgatttt ctggcgcagc gggggcaagg
     3301 acaggttgaa caggtctttg ccagagcggt aaatatcgca ctcccggctc gccagcagtt
     3361 gctgacgctg ctttgtgaag agtacgacaa tgcgcctaac agttgtcggt tggcactcac
     3421 tcactttaat ggtctgttcc ggcatgatga taaggttcag tttgacgatc aaggcattac
     3481 gattggtcaa catcatcata tagagatgag tcattgccag cgttggctgt ccccaacctt
     3541 gcaaatgacc gctgtgaatt ttcaccttat cgcctggcaa cagtggtacg acattattca
     3601 tcagcacctg ggggaaaatg aaaccctgtt taattatcgc ggcgataatc cgttttatca
     3661 ggcgttaaat aaagaactac atattaaacg acgggcagtt attcaggccg taaacgataa
     3721 acaaaatatc gcctcagcag tcgccagtat gatggggtta gggattggcc ttacgccatc
     3781 agccgatgat tatctgaccg gactggtact tattttattt atttccggac atccggcgga
     3841 aaaatacaaa gaggaatttt atctcggcct gcaacgcggc agaaataata ccacgttatt
     3901 aagtgccatc acgctggaag ccgcattaca acaacgctgc cgggaaaata ttcatcgttt
     3961 tattcacaac attatttatg acatccctgg gaacgcaact caggcaatag aaaaaattaa
     4021 acatattggc tccagttccg gctgcgacat gctgtatggc atggccgatg gttgtgcgct
     4081 gagtcaaacc tacggaggga attatgtcag ttaaaatagt cattaaaccg aatacctatt
     4141 ttgattctgt ctcgctgatg tctatctcca cgcgtgcaaa taaactcgac ggcgtcgagc
     4201 aggcatttgt ggcgatggcg accgaaatga acaaaggcgt gttgaagaat ttaggactgc
     4261 tgacgccgga gctggagcag gcgaaaaacg gcgacctgat gattgtcatc aatggtaaat
     4321 cgggtgtgga caacgagcag ttgctggcgg agattgaaga actgttcaac accaaagcgc
     4381 aaagcggctc gcacgaggcg cgttacggca ctattgccag cgccaaaaag catatcccgg
     4441 aaagtaacct ggcagtgatt tcggtcaacg gtctgtttgc cgctcgcgaa gcgcgtcagg
     4501 cgctgcaaaa tgacctcaac gtgatgctgt tttccgataa tgtctcagtt gaagatgaac
     4561 tggcgctcaa acagttggcc catgaaaaag ggctgctgat gatggggcca gactgcggca
     4621 cggcgattat caacggcgcg gcgctctgct ttggtaacgc cgtgcgtcgc ggcaacatcg
     4681 gtattgttgg cgcatctggc accggcagcc aggaattgag cgtccgtatc catgaatttg
     4741 gtggcggcgt ttcacaactg atcggcaccg gcgggcgcga cctgagcgag aaaatcggcg
     4801 gactgatgat gctcgatgcc atcagcatgc tggaaaacga tccgcaaact gaaatcattg
     4861 tgcttatctc caaaccgcct gcgcctgcgg tggcccgcaa agtgctggaa cgcgcacgcg
     4921 cctgccgcaa gccagtggtg gcctgcttcc tcggtcgtgg cgaaacgcca gtggatgagc
     4981 aggggctaca gtttgctcgc ggcagcaaag aggcggcatt gaaagcggtg atgctctccg
     5041 gcgtgaaaca agaacatctc gatctgcata cgcttgacca gccgttgatt gcggatgtgc
     5101 gcgcgcgtct gcaaccgcag cagaaataca ttcgtggtct gttctgcggc ggtacgctgt
     5161 gtgacgaaac cctgttcgcg gtgatggaaa aacatggcga tgtctacagc aatatccagc
     5221 ccgatcctga attccgcctg caagatatca accgcagcat caaacacacc ttcctcgact
     5281 ttggcgatga tgacttcacc aacggcaagc cgcatccaat gattgacccg accaaccgta
     5341 tcagccgctt gatcgaagaa gcgcgcgatc cagaagtggc ggtgatcgtg atggattttg
     5401 tgctcggatt tggatcgcat gaagatccgg tcggttccac catcgaggcg atcaaagaag
     5461 cgaaagcgat cgccgctgcc gaaggacgcg agttgatcat tctcgcctat gtgctgggca
     5521 ccgatctcga tacgccatca ttagaacaac aaagccagat gctgcttgat gccggagtga
     5581 ttctggcgag cagcagcacc aataccggat tgctggcgcg tgaatttatc tgcaaagggg
     5641 aggaagcctg atgagccagt cactgtttag ccaaccgttg aacgttatta acgtcggtat
     5701 cgccatgttt agcgatgatc tgaaaaagca gcatgtagaa gtgacccaac tcgactggac
     5761 gccgccgggg cagggcaata tgcaggtggt gcaggcactg gacaacattg ccgattcgcc
     5821 gctggcggac aaaatcaccg ccgctaacca gcaggcgctg gagcgcatta tccagtcgca
     5881 tccagtgctg attggttttg atcaggcgat taacgtggtg ccgggcatga cggcgaaaac
     5941 cattcttcac gccgggccgc cggtcacctg ggaaaaaatg tgcggcgcga tgaaaggcgc
     6001 ggtcaccgga gcgctggtgt ttgaaggact ggcgaaagat ctcgacgagg cggctgagct
     6061 ggcggcttcc ggggagatca ccttctcgcc gtgccacgag cacgactgtg tgggatcgat
     6121 ggcgggcgtc acctcggcct cgatgtttat gcacatcgtg aaaaacaaaa cctatggcaa
     6181 catcgcttat accaacatga gcgagcagat ggcgaagatt ttgcgtatgg gcgctaacga
     6241 ccagagcgtg atcgaccgcc tcaactggat gcgcgatgtg caggggccaa tgctgcgtga
     6301 cgcgatgaaa attatcggcg agatcgatct gcgcttaatg ctggcgcagg cgctgcatat
     6361 gggcgatgaa tgccataacc gcaataacgc cgggacgacg ctgctgattc aggcgctgac
     6421 gccggggatt attcaggcgg gttattccgt tgagcaacag cgcgaagtgt ttgagtttgt
     6481 cgccagcagc gattacttct ccggcccaac gtggatggcg atgtgtaaag cggcgatgga
     6541 tgcggcgcac ggcattgaat acagcaccgt ggtgaccacc atggcgcgta acggcgtcga
     6601 gttcggcctg cgggtcagcg gcctgccggg gcaatggttt accggcccgg cgcagcaggt
     6661 catcggcccg atgtttgccg gttataagcc ggaagattcg gggctggata tcggcgacag
     6721 cgccatcacc gaaacctacg gtatcggcgg atttgcgatg gcgaccgcgc ccgcgatcgt
     6781 tgcgctggtg ggcggcacgg tggaagaggc tatcgatttc tcccgtcaga tgcgtgaaat
     6841 cacccttggc gaaaacccca acgtcaccat tccgctgctc ggttttatgg gcgtgccgtc
     6901 ggcaatcgac atcacccgcg tgggtagcag cggcattctg ccggtgatca acaccgccat
     6961 tgcccataaa gatgcgggcg tcggcatgat tggcgcgggc attgtgcatc cacccttcgc
     7021 ctgcttcgag aaagccattc ttggctggtg cgaacgttac ggcgtctgac ctgcaaagta
     7081 cgcgttgtct ctgccggatg cggcgtgaac gccttatccg gcctacgagt ggcacgagaa
     7141 ttgtaggcct gataagcgta gcgcatcagg cagtctggcg ttggtcataa ccccatcacc
     7201 ctctgtcgcg gacataacaa catgaaagaa cttgtggtcg ttgccattgg tggcaacagc
     7261 attatcaaag ataacgccag ccagtcgatt gagcatcagg cggaggcggt gaaagccgtg
     7321 gccgatacgg tgctggaaat gctggcttcc gattacgaca ttgtgctgac ccacggcaac
     7381 gggccgcagg tcgggctgga tttacgccgt gcggagattg cccacgagcg cgaagggctg
     7441 cccttaacgc cgctggcgaa ctgtgtggcg gatacgcaag gtggcattgg ctatctgatc
     7501 cagcaggcgc tgaacaaccg actggcgcgt cacggcgaga aaaaagccgt cactgtggtg
     7561 actcaggtgg aagtggataa aaacgatccg ggttttgccc atcccaccaa gcccatcggc
     7621 gcattcttta gtgaaagcca gcgtgacgaa ctacaaaagg caaaccctga ctggcgtttt
     7681 gttgaagatg ccggacgggg ctatcgccgc gtggtcgcct cgccggaacc gaaacgtatt
     7741 gtcgaagcac ctgccattaa ggcgctgatc caacaaggct ttgtggtgat tggcgcgggc
     7801 ggcggtggaa ttcctgtggt gcgcaccgaa gcgggagatt accaaagcgt ggacgcggtt
     7861 atcgacaaag atctctccac cgcgctactg gcccgcgaaa ttcacgccga cattctggtg
     7921 atcaccaccg gcgtcgaaaa agtctgtatc cactttggca agccgcagca acaggcgctc
     7981 gatcgcgtag atattgccac catgacccgc tatatgcagg aagggcattt cccacctggc
     8041 agcatgttgc caaaaatcat cgccagcctg acgttcctgg aacaggacgg caaagaagtg
     8101 attatcacca cgccggaatg cctgcctgcg gcgctacgcg gcgaaacggg cacccatatt
     8161 attaaaacct aaggacgtaa gatgaaagaa aacaatagcc gccgtgaatt tctgagccag
     8221 agcggtaaga tggtcaccgc cgccgcgctg tttggtacct cagtgccgct cgcccatgcg
     8281 ggggtagctg gcaccctaaa ctgcgaagcg aacaacacca tgaaaatcac tgacccgcat
     8341 tactatctcg ataacgtgct gctggaaacc ggttttgact acgaaaatgg cgtggcggta
     8401 cagacccgca cggcgcgcca gaccgtggag attcaggacg gtaaaattgt tgccctgcgc
     8461 gagaacaagc agcatccgga cgccacgctg ccgcactatg acgctggcgg taagctgatg
     8521 ctgcccacca cccgcgatat gcatattcat ctcgacaaaa ccttctacgg cgggccgtgg
     8581 cgctcgctca atcgtccggc aggcaccact atccaggaca tgatcaaact cgagcagaaa
     8641 atgctgccgg aactgcaacc gtacacgcag gaacgggcgg aaaaactgat cgatttattg
     8701 cagtcgaaag gcaccactat tgcccgcagc cactgcaata tcgaaccggt ttccggcctg
     8761 aaaaatctgc aaaatttgca ggcggtgctg gcgcgacgtc agacgggctt cgagtgtgag
     8821 atcgtcgcct tcccgcagca cggtttgctg ctgtcgaaat cggaatcctt aatgcgcgaa
     8881 gcgatgcagg cgggggcgca ttacgtcggc gggctggacc cgaccagtgt tgatggcgcg
     8941 atggaaaaat ccctcgacac catgttccag attgcgctgg actatgacaa aggcgtcgat
     9001 attcacctgc acgaaaccac gccggcaggc gtggcagcca tcaattatat ggttgaaaca
     9061 gtggagaaaa cgccacagct gaagggcaag ctgaccatca gccacgcctt tgcgctggca
     9121 acgctcaacg aacaacaggt agatgaactg gcgcaccgga tggcggcgca gcgaatttcg
     9181 atcgcttcga cggtgccgat tggcacgctg catatgccgc tcaaacagct gcacgacaaa
     9241 ggcgtaaaag tgatgaccgg caccgacagc gttatcgacc actggtcgcc ttacggcctg
     9301 ggcgacatgc tggaaaaagc caatctgtac gcgcagctct atattcgtcc taacgaacag
     9361 aacctctccc gctctctgtt tttagccact ggcgatgtat tgccgctcaa cgaaaaaggc
     9421 gagcgcgtgt ggcccaaagc gcaggatgat gccagttttg tgctggtgga cgcctcctgt
     9481 tccgccgagg cggtggcgcg tatttcgccg agaacggcga cgttccataa agggcaactg
     9541 gtgtggggga gtgtggcagg ttgatacgaa cttgatatgt ttgcaacggt gaacagtaag
     9601 agatttaagc cccagggagt ggggcggcct gagtatgagt gtgtcggcag aaatggacat
     9661 tatctttgaa gaatatgccc ttattgacgt tgtgtagata actatttgtc tacgtgaaaa
     9721 tatcatcagt tttgccgatt tttgtctttt acggatagca aatatcacac ttataggcgc
     9781 tcgccttatg gggaacgttg ctgctctgtt tcattcaggc tcgcggcatg ttagggctgg
     9841 atcgggtggt ttaaatattg gctatattca atggacgcgt tttgccgcga tgacatatca
     9901 ggcatcgtca aatacacata gctaatcagg agtaaacaca atgaagatca aagctgttgg
     9961 tgcatattcc gctaaacaac cgcttgaacc gatggatatc acccggcgtg aaccgggacc
    10021 gcatgatgtc aaaatcgaaa tcgcttactg tggcgtctgc cattccgatc tccaccaggt
    10081 ccgttcggag tgggcgggga cggtttaccc ctgcgtgccg ggtcatgaaa ttgtggggcg
    10141 cgtggtagcc gttggtgatc aggtagaaaa acatgcgccg ggcgatctgg tcggtgtcgg
    10201 ctgcattgtc gacagttgta aacattgcga agagtgtgaa gacgggctgg aaaactactg
    10261 tgatcacatg accggaacct ataactcgcc gacaccggat gaaccgggcc atactctggg
    10321 aggctactca caacagatcg tcgttcatga gcgatatgtt ctgcgtattc gtcacccgca
    10381 agagcagctg gcggcggtgg ctcctttatt gtgtgcagga atcaccacgt actcgccgct
    10441 acgccactgg caggccgggc cgggtaaaaa agtgggcgtg gtcggcatcg gcggtctggg
    10501 acatatgggg attaaactgg cccacgcgat gggggcgcat gtggtggcat ttaccacttc
    10561 tgagtcaaaa cgcgaagcgg caaaagccct gggggccgat gaagttgtta actcacgcaa
    10621 tgccgatgag atggtggctc atgtgaagag tttcgatttc attttgaata cagtagctgc
    10681 gccacataat ctcgacgatt ttaccacctt gctgaagcgc gatggcacca taacgctggt
    10741 tggtgcgcct gcgacaccgc ataaatcgcc ggaagttttc aacctgatca tgaaacgccg
    10801 cgcgatagct ggttctatga ttggcggcat tccagaaact caggagatgc tcgatttttg
    10861 cgccgaacat ggcatcgtgg ctgatataga gatgattcgg gccgatcaaa ttaatgaagc
    10921 ctatgagcga atgctgcgtg gtgatgtgaa atatcgtttt gttatcgata atcgcacact
    10981 aacagactga aaaaaattaa taaatatcct gtggtttaac atattaattt cgctctcctt
    11041 aactttttag ttaaggagag cgaaataata tcaaagtagt ggtaaaccta tagcgtaaat
    11101 tcagattgtt aaattaactc tactacttta cacgttagtt atgagcgatt tctgatagtg
    11161 tctggtttaa tcagagcttt attatctgcg acgtttattt ttatttaaga gagccacctg
    11221 caagttgtta ttccaccaga gagtgaatcg caaagcaggt catcatttca tctgtatatc
    11281 tgtatgccaa atggcattcc ccctcctttt tcgccgatat tttgttgtga tcgacgaagt
    11341 ttcgcttaaa aaagcaccag cagtggtttc gcagctatat ggtgtataaa aaatgttctc
    11401 atacagatgt tttgtgaatg tgtgggttga cattcatatg aaaaaaatca taattccatc
    11461 atgtttgtgt gggggctttt ctgtatctta cgcatcgcac tcaagcctga cagaaaatat
    11521 gctgtaaggc tcatatcaaa aaccgccatt agctcatcag gaagagcaga cgacaaccag
    11581 gattgttgta tggtacgggg ttcgaggcct cgatggcggt ccaacttttc aaaactcttc
    11641 tgaatcagat ccccttatta tcatccctgc aaagtggaac attgccattg tttggctatt
    11701 caggacgggt cagaccaatg aaaaagccca cacaggggag agtaggctga aatgggaagc
    11761 taaagactca agtaaactta tcggaaataa ggaccacgca ttacgggggc tatcatcgcc
    11821 gatggttggg attcggcaaa tcaggttgat tacgtagaga gtaaattatc tgctcaccgc
    11881 tgcgtcaccc cttcgtaaat caggcgtagc gcgaatacac caataattgc accaataacc
    11941 cgactggcaa cgcgttgcat acgcccataa gcacgacgca cagcgggcaa agaaaacgcc
    12001 tggcttagaa agactcgcca gataattgat gtgagcacaa tccccgccca ggccattaat
    12061 cgtgcccatg ttggtgtttc ggcatttaat gttactgaga aaatactgat aaaaaataaa
    12121 acggtttgcg ggttagagag atcggtaatt aatccacggc ggaaaaagat ataccagggg
    12181 gcactaatcg gttgttgtag tgtgctcatt tgcggtgttg actggcggcg catgctgcac
    12241 cacgcaaacc ataagagata agcgccgccg acgattctga taagcgaaaa aatctcctca
    12301 cactgcgtaa ttagcgttgc aagaccaaac aaacccaacc cggaataaaa tgcatcgccc
    12361 agcgccacgc ccagcccggt caacaccccc gcgcgtcgac cggaagccag gctggtttgt
    12421 actaccacaa agagattggc tcccggatta aaaaaagtaa tcacgaacaa tcctacggtc
    12481 aggtaaacgg cgtgcaaagg atccatagtg atttcatcca taaataagtg aagtaacttc
    12541 atcatatttc taccaaaaat aatcgggtgc gagagagatc acaaagtgtc ttatttccgg
    12601 ttactggcgt ttatgccctg actgaactaa ttattaatca acccaataat gtgggtgggt
    12661 gatagtgtga taacaactct ggagccgtaa tatgaaaata atctctaaaa tgttagtcgg
    12721 tgcgttagcg tttgccgtta ccaatgtcta tgccgcagaa ttaatgacca aagcggaatt
    12781 tgaaaaggtt gcatcgcaat atgaaaaaat aggtgatatt tcaaccagta atgaaatgtc
    12841 gaccgcagat gcgaaagaag atttgatcaa aaaagccgat gaaaaagggg ctgatgtgtt
    12901 ggtactgacc tctggtcaaa ctgacaataa gatccacggc acggcaaata tttataagaa
    12961 gaagtaattc tgaatcctat gtaaacatcc ccgatgcgtt agtttatcgg tgatcatcat
    13021 ctatcgaaat ttatgccgga taaagcgttc gcgctgcatt cggcagttca gcttttcagc
    13081 cgccgccaga acgtcgtccg gctgatacct aaataattcg ccgctgctgt tttatcgcca
    13141 ttaaatttct ccagtgcctg ttgtgctgtc agcaagcctg gaatgggagt cttcgccgac
    13201 tcgcgcgcca gttccggcag tagcagctgc aaaaattgcg gcgttaaatc cggcgtcgat
    13261 tccacactta aaaacagcgc cagtcgttcc atcatattgc gcagttcacg aatattgccc
    13321 ggccagtcgt agtgcaataa tagaatctga caggtctcta atccctgacg taatgccgca
    13381 gaaaaaggga cagagagtgc cgccagagac attttcaaaa agctttccgc cagcggcaga
    13441 atatccgcca cccgctcgcg tagcggcggc agttgtagac gcaaaatact cagccgataa
    13501 aacaggtcac ggcgaaactg cccttgctgc atatcttctt ccagattgca gtgagtggcg
    13561 ctaatgaccc gcacatccac cggaacaggc tgatgcccgc cgacgcgggt gacctctttt
    13621 tcttccagca cccgcagcag ccgagtctgc aacggcagcg gcatttcgcc tatctcgtca
    13681 agaaacagcg taccaccgtg ggcgatttca aacagcccgg cgcgtcctcc gcgtcgcgag
    13741 ccggtaaacg ccccttcctc atagccaaac agctccgctt ccagcagcga ttcggcaatc
    13801 gccccgcagt taacggcaac aaacggatgt gactttttgc cctgtcgcgc atcgtggcgg
    13861 gaaaaatatt cccgatgaat cgcctgggcc gccagctctt tgcccgtccc cgtttccccc
    13921 tcaatcaaca ccgccgcact ggagcgggca tacagcaaaa tagtctgccg cacctgttcc
    13981 atctgtggtg attgaccgag catatcgccc agcacgtaac gagtacgcag ggcgttgcgg
    14041 gtggcatcgt gagtgttatg gcgtaacgac atgcgcgtca tatccagcgc atcgctgaat
    14101 gcctggcgca cggtggcggc ggaatagata aaaattccgg tcattccggc ttcttctgcc
    14161 agatcggtaa tcagccctgc gccgaccacc gcttcggtgc cgttggcttt caactcattg
    14221 atttgcccgc gggcgtcttc ttcggtgatg tagctacgtt ggtcgaggcg caaattaaag
    14281 gtcttttgaa acgccaccag cgctggaatg gtttcctgat aggtgacaac accgatagaa
    14341 gaggtgagtt ttccggcttt tgccagtgcc tgtaacacat cgtagccgct cggtttaatc
    14401 aaaataactg gcactgacag gcgactttta agatatgcgc cgttagagcc agcagcgatg
    14461 atggcgtcgc accgttcgtt ggccagtttc ttgcggatgt aggtcaccgc tttttcaaag
    14521 ccaagctgga taggggtgat attcgccagg tgatcaaact cgaggctgat atcgcgaaac
    14581 agctcgaaca ggcgcgttac agataccgtc cagataaccg gtttgtcgtc attcagccgt
    14641 ggtggatgtg ccatagcgca ccgcaaagtt aagaaaccga atattgggtt tagtcttgtt
    14701 tcataattgt tgcaatgaaa cgcggtgaaa cattgcctga aacgttaact gaaacgcata
    14761 tttgcggatt acttcatgaa tttatcttta actcattgaa attaaatgtt taattttatt
    14821 aaggcaattg tggcacaccc attgctttgt ctttatcaac gcaaataaca agttgataac
    14881 aaaggatggg ctatgtctct acactctcca ggtaaagcgt ttcgcgctgc actgactaaa
    14941 gaaaatccat tgcagattgt tggcactatc aacgctaacc atgcgctgct ggcgcagcgt
    15001 gccggatatc aggcgattta tctctccggc ggtggcgtgg cggcagggtc gctggggctg
    15061 cccgatctcg gtatttctac tcttgatgat gtgctgactg acattcgccg tatcaccgac
    15121 gtttgttcgc taccgctgct ggtggatgcg gatatcggtt ttggttcttc tgcttttaac
    15181 gtggcgcgca ccgtgaaatc gatgattaaa gccggtgcgg caggattgca tattgaagat
    15241 caggttggtg cgaaacgctg cggtcatcgc ccgaacaaag cgatcgtctc gaaagaggaa
    15301 atggtggatc ggatccgtgc ggcggtggat gcgaaaaccg atcctgattt tgtgatcatg
    15361 gcgcgcaccg atgcgctggc ggtagagggg ctggatgcgg cgatcgagcg tgcgcaggcc
    15421 tatgttgaag cgggtgccga aatgctgttc ccggaggcga ttaccgaact cgccatgtat
    15481 cgccagtttg ccgatgcggt gcaggtaccg atcctcgcca acattaccga atttggcgca
    15541 acaccgctgt ttaccaccga cgaattacgc agcgcccatg tcgcaatggc gctctacccg
    15601 ctttcagcgt ttcgcgccat gaaccgcgcc gctgaacatg tctacaacat cctgcgtcag
    15661 gaaggcacac agaaaagcgt catcgacacc atgcagaccc gcaacgagct gtacgaaagc
    15721 atcaactact accagtacga agagaagctc gacgacctgt ttgcccgtgg tcaggtgaaa
    15781 taaaaacgcc cgttggttgt attcgacaac cgatgcctga tgcgccgctg acgcgactta
    15841 tcaggcctac gaggtgaact gaactgtagg tcggataaga cgcatagcgt cgcatccgac
    15901 aacaatctcg accctacaaa tgataacaat gacgaggaca atatgagcga cacaacgatc
    15961 ctgcaaaaca gtacccatgt cattaaaccg aaaaaatcgg tggcactttc cggcgttccg
    16021 gcgggcaata cggcgctctg caccgtgggt aaaagcggca acgacctgca ttaccgtggc
    16081 tacgatattc ttgatctggc ggaacattgt gaatttgaag aagtggcgca tctgctgatc
    16141 cacggcaaac tgccaacccg tgacgaactc gccgcctaca aaacgaaact gaaagccctg
    16201 cgtggtttac cggctaacgt gcgtaccgtg ctggaagcct taccggcggc gtcacacccg
    16261 atggatgtta tgcgcaccgg cgtttccgcg ctcggctgca cgctgccaga aaaagagggg
    16321 cataccgtct ctggcgcacg ggatattgcc gacaaactgc tggcgtcact tagctcgatt
    16381 cttctctact ggtatcacta cagccacaac ggcgaacgca ttcagccgga aaccgatgac
    16441 gactctatcg gcggtcactt cctgcatctg ctgcacggcg aaaagccgtc gcaaagctgg
    16501 gaaaaggcga tgcatatttc gctggtgctg tacgccgaac acgagtttaa cgcttccacc
    16561 tttaccagcc gggtgattgc gggcactggc tctgatatgt attccgccat tattggcgcg
    16621 attggcgcac tgcgcgggcc gaaacacggc ggagcgaatg aagtgtcgct ggagatccag
    16681 caacgctacg aaacgccgga cgaagccgaa gctgatatcc gtaagcgggt ggaaaacaaa
    16741 gaagtggtca ttggttttgg gcatccggtt tataccatcg ccgacccgcg ccaccaggtg
    16801 atcaaacgcg tggcaaagca gctctcgcag gaaggcggct cgctgaagat gtacaacatc
    16861 gccgatcgcc tggaaacagt gatgtgggag agcaaaaaga tgttccccaa tctcgactgg
    16921 ttctccgctg tttcctacaa catgatgggt gttcccaccg agatattcac accactgttt
    16981 gttatcgccc gcgtcactgg ctgggcggcg cacattatcg aacaacgtca ggacaacaaa
    17041 attatccgtc cttccgccaa ttatgttgga ccggaagacc gccagtttgt cgcgctggat
    17101 aagcgccagt aaacctctac gaataacaat aaggaaacgt acccaatgtc agctcaaatc
    17161 aacaacattc gcccggaatt tgatcgtgaa atcgttgata tcgtcgatta cgtgatgaac
    17221 tacgaaatca gctccagagt agcctacgac accgcacatt actgcctgct cgacacgctc
    17281 ggctgtggtc tggaagctct cgaatatccg gcctgtaaaa aactgctggg gccaattgtc
    17341 cccggcaccg tcgtacccaa tggcgtgcgc gtccccggaa ctcagtttca gctcgacccc
    17401 gtccaggcgg catttaacat tggcgcgatg atccgttggc tcgatttcaa cgatacctgg
    17461 ctggcggcgg agtgggggca tccttccgac aacctcggcg gcattctggc aacggcggac
    17521 tggctttcgc gcaacgcggt cgccagcggc aaagcgccgt tgaccatgaa acaggtgctg
    17581 accgcaatga tcaaagccca tgaaattcag ggctgcatcg cgctggaaaa ctcctttaac
    17641 cgcgtcggcc tcgaccacgt tctgttagtg aaagtggctt ccaccgccgt ggtcgccgaa
    17701 atgctcggcc tgacccgcga ggaaattctc aacgccgttt cgctggcatg ggtagacgga
    17761 cagtcgctgc gcacctatcg ccatgcgccg aacaccggta cgcgtaaatc ctgggcggcg
    17821 ggcgatgcca cttcccgcgc ggtacgtctg gcactgatgg cgaaaaccgg cgaaatgggt
    17881 tatccgtcag ccctgactgc gccggtgtgg ggcttctacg acgtctcctt taaaggcgaa
    17941 tcgttccgct tccagcgccc gtatggttct tacgtgatgg aaaatgtgct gttcaaaatc
    18001 tccttcccgg cggagttcca ctcccagacg gcagttgaag cagcgatgac gctctatgaa
    18061 cagatgcagg cagcaggcaa aacggcggcg gatatcgaaa aagtgaccat tcgcacccac
    18121 gaagcctgta ttcgcatcat cgacaaaaaa gggccgctca ataacccggc tgaccgcgac
    18181 cactgcattc agtacatggt ggcgatcccg ctgctgttcg ggcgcttaac ggcggcagat
    18241 tacgaggaca acgttgcgca agataaacgc atcgacgctc tgcgcgagaa gatcaattgc
    18301 tttgaagatc cggtgtttac cgctgactac cacgacccgg aaaaacgcgc catcgccaat
    18361 gccataaccc ttgagttcac cgacggcacg cgatttgaag aagtggtggt ggagtaccca
    18421 attggtcatg ctcgccgccg tcaggatggc attccgaagc tggtcgataa attcaaaatc
    18481 aatctcgcgc gccagttccc gactcgccag cagcagcgca ttctggaggt ttctctcgac
    18541 agaactcgcc tggaacagat gccggtcaat gagtatctcg acctgtacgt catttaagta
    18601 aacggcggta aggcgtaagt tcaacaggag agcattatgt cttttagcga attttatcag
    18661 cgttcgatta acgaaccgga gcagttctgg gccgagcagg cccggcgtat tgactggcag
    18721 acgcccttta cgcaaacgct cgaccacagc aacccgccgt ttgcccgttg gttttgtgaa
    18781 ggccgaacca acttgtgtca caacgctatc gaccgctggc tggagaaaca gccagaggcg
    18841 ctggcattga ttgccgtctc ttcggaaaca gaggaagagc gtacctttac cttccgccaa
    18901 ctgcatgacg aagtgaatgc ggtggcgtca atgctgcgct cgctgggcgt gcagcgtggc
    18961 gatcgggtgc tggtgtatat gccgatgatt gccgaagcgc atattaccct gctggcctgc
    19021 gcgcgcattg gtgctattca ctcggtggtg tttgggggtt ttgcctcgca cagcgtggcg
    19081 gcgcgaattg atgacgctaa accggtgctg attgtctcgg ctgatgccgg ggcgcgcggc
    19141 ggtaaaatca ttccgtataa aaaattgctc gacgatgcga taagtcaggc acagcatcag
    19201 ccgcgtcacg ttttactggt ggatcgcggg ctggcgaaaa tggcgcgcgt tagcgggcgg
    19261 gatgtcgatt tcgcgtcgtt gcgccatcag cacatcggcg cgcgggtgcc ggtggcatgg
    19321 ctggaatcca acgaaacctc ctgcattctc tacacctccg gcacgaccgg caaacctaaa
    19381 ggtgtgcagc gtgatgtcgg cggatatgcg gtggcgctgg cgacctcgat ggacaccatt
    19441 tttggcggca aagcgggcgg cgtgttcttt tgtgcttcgg atatcggctg ggtggtaggg
    19501 cattcgtata tcgtttacgc gccgctgctg gcggggatgg cgactatcgt ttacgaagga
    19561 ttgccgacct ggccggactg cggcgtgtgg tggaaaattg tcgagaaata tcaggttagc
    19621 cgcatgttct cagcgccgac cgccattcgc gtgctgaaaa aattccctac cgctgaaatt
    19681 cgcaaacacg atctttcgtc gctggaagtg ctctatctgg ctggagaacc gctggacgag
    19741 ccgaccgcca gttgggtgag caatacgctg gatgtgccgg tcatcgacaa ctactggcag
    19801 accgaatccg gctggccgat tatggcgatt gctcgcggtc tggatgacag accgacgcgt
    19861 ctgggaagcc ccggcgtgcc gatgtatggc tataacgtgc agttgctcaa tgaagtcacc
    19921 ggcgaaccgt gtggcgtcaa tgagaaaggg atgctggtag tggaggggcc attgccgcca
    19981 ggctgtattc agaccatctg gggcgacgac gaccgctttg tgaagacgta ctggtcgctg
    20041 ttttcccgtc cggtgtacgc cacttttgac tggggcatcc gcgatgctga cggttatcac
    20101 tttattctcg ggcgcactga cgatgtgatt aacgttgccg gacatcggct gggtacgcgt
    20161 gagattgaag agagtatctc cagtcatccg ggcgttgccg aagtggcggt ggttggggtg
    20221 aaagatgcgc tgaaagggca ggtggcggtg gcgtttgtca ttccgaaaga gagcgacagt
    20281 ctggaagacc gtgaggtggc gcactcgcaa gagaaggcga ttatggcgct ggtggacagc
    20341 cagattggca actttggccg cccggcgcac gtctggtttg tctcgcaatt gccaaaaacg
    20401 cgatccggaa aaatgctgcg ccgcacgatc caggcgattt gcgaaggacg cgatcctggg
    20461 gatctgacga ccattgatga tccggcgtcg ttggatcaga tccgccaggc gatggaagag
    20521 taggtcggat aaggcgctcg cgccgcatcc gacaccgtgc gcagatgcct gatgcgacgc
    20581 tgacgcgtct tatcatgcct acaggcctga accgtaggtc ggataaggcg ctcgcgccgc
    20641 atccgacacc atgcgcagat gcctgatgcg acgctgacgc gtcttatcat gcctacccac
    20701 tgtttttaca cagataagtt tcccccgcct ttttgtactc attcatataa gaaatatatc
    20761 cccatacgaa aacgattgct ttttatcttc agatgaatag aatgcggcgg attttttggg
    20821 tttcaaacag caaaaagggg gaatttcgtg tcgcaagata acaactttag ccaggggcca
    20881 gtcccgcagt cggcgcggaa aggggtattg gcattgacgt tcgtcatgct gggattaacc
    20941 ttcttttccg ccagtatgtg gaccggcggc actctcggaa ccggtcttag ctatcatgat
    21001 ttcttcctcg cagttctcat cggtaatctt ctcctcggta tttacacttc atttcttggt
    21061 tacattggcg caaaaaccgg cctgaccacc catcttcttg ctcgcttctc gtttggtgtt
    21121 aaaggctcat ggttgccttc actgctgctg ggcggcaccc aggttggctg gtttggcgtt
    21181 ggcgtggcga tgtttgctat tccggtgggc aaggcaaccg ggctggatat taatttgctg
    21241 attgccgtct ccggtttact gatgaccgtc accgtcttct ttggcatttc ggcgctgaca
    21301 gttctttcgg tgattgcggt tccggctatc gcctgtcttg gcggttattc cgtgtggctg
    21361 gccgttaacg gcatgggcgg cctggacgca ttaaaagcgg tcgttcccgc acaaccgtta
    21421 gatttcaatg tcgcgctggc gctggttgtg gggtcattta tcagtgcggg cacgctcacc
    21481 gctgactttg tccggtttgg tcgtaatgcc aaactggcgg tgctggtggc gatggtggcc
    21541 tttttcctcg gcaactcgtt gatgtttatt ttcggtgcag cgggcgcggc ggcactgggg
    21601 atggcggata tctctgatgt gatgattgct cagggcctgc tgctgcctgc gattgtggtg
    21661 ctggggctga atatctggac caccaacgat aacgcgctct atgcgtcggg tttaggtttc
    21721 gccaacatta ccggtatgtc gagcaaaacc ctttcggtga ttaacggtat tatcggtacg
    21781 gtctgcgcat tatggctgta taacaatttt gtcggctggt tgaccttcct ttcggcagct
    21841 attcctccgg tgggcggcgt gatcatcgct gattatctga tgaaccgtcg ccgctatgag
    21901 cactttgcga ccacgcgtat gatgagtgtc aattgggtgg cgattctggc tgtcgcgctg
    21961 gggattgccg caggccactg gttaccggga attgttccgg tcaacgcggt attaggtggc
    22021 gcgctgagct atctgatcct taacccgatt ttgaatcgta aaacgacagc agcaatgacg
    22081 catgtggagg ctaacagtgt cgaataatgc tttacaaaca attattaacg cccggttacc
    22141 cggcaaagag gggctgtggc agattcattt tcacgacgga aaaatcagcg ccattgatgc
    22201 gcaatccggc gtgatgcccg taactgaaaa cagcctggat gccgaacaag gtttagtttt
    22261 accgccgttt gtggagccgc atattcacct ggacaccacg caaaccgccg gacaaccgaa
    22321 ctggaatcag tccggcacgc tgtttgaagg cattgaacgc tgggccgagc gcaaagcgtt
    22381 attaactcat gacgatgtga aacaacgcgc atggcaaacg ctgaaatggc agattgccaa
    22441 cggcattcag catgtgcgta cccatgtcga tgtttcggac gcaacgctga ctgcgctgaa
    22501 agcaatgctg gaagtgaaac aggaagttgc gccgtggatt gatctacaaa tcgtcgcctt
    22561 cccgcaggaa gggattttgt cgtatcccaa tggtgaagcg ttgctggaag aggcgttacg
    22621 cttaggggca gacgttgttg gggcgattcc gcattttgaa tttacccgtg aatatggcgt
    22681 ggagtcgctg cataaaacct tcgccctggc gcaaaaatac gaccgtctca tcgatgttca
    22741 ctgtgacgag attgatgatg agcaatcacg ctttgtcgaa accgttgctg ccctggcgca
    22801 ccgtgaaggc atgggcgcgc gagtcaccgc cagccatact acggcaatgc actcctataa
    22861 cggggcgtat acttcgcgcc tgtttcgttt gctgaaaatg tccggtatta actttgtcgc
    22921 caacccgttg gtcaatattc atctgcaagg acgtttcgat acgtatccaa aacgtcgcgg
    22981 catcacgcgc gttaaagaga tgctggagtc cggcattaac gtctgctttg gtcacgatga
    23041 tgtcttcgat ccgtggtatc cgctgggaac ggcgaatatg ctgcaagtgc tgcatatggg
    23101 gctgcatgtt tgccagctga tgggctatgg gcagattaac gacggcctga atttaatcac
    23161 ccaccacagt gccagaacgt tgaatttgca ggattacggc attgccgccg gaaacagcgc
    23221 caacctgatt atcctgccgg ctgaaaatgg gtttgacgcg ctgcgccgtc aggttccggt
    23281 gcgctattcg gtacgtggcg gcaaggtgat tgccagcaca aaaccggcac aaaccaccgt
    23341 atatctggag cagccagaag ccatcgatta caaacggtaa tcggctgggt taccgcgagc
    23401 gtagtttatg ccggatgcgg cgtgaacacc ttatccggcc tacgtagatc actgaaattg
    23461 taggcctgat aagcggagcg catcaggcaa ttttgcttat ttaaactgaa gactcaactt
    23521 taaaatcttt gaaataatat tgcttatccc ggtcgtttat ttcgcgaata acccgacaag
    23581 gaacgcctgc agccacgacg tttggtggaa tgtcttttgt gacgacacta cccgcgccaa
    23641 taacagaatt atccccgatg gtgatgcctg gattaataac cacatgacat ccgatccaga
    23701 cgttattgcc aatcgttatc ggaaaagagt acatctctcc gttttttctc aattcatggt
    23761 gtaccgggtg tcccgtaacg gaaagagtaa cgttgggtgc aatcagtacg ttatcaccga
    23821 tcgttaccgt gtagtcgtcg acaatggtta aattgaaatt tgcataaaaa ttgcggccta
    23881 tatggatgtt ggaaccgtaa gagaaataga cgggggggtc tacccaggcg ttttccccta
    23941 ccgtggcaaa catttcttta atcagacttt cccttttttc aaattctgat ggatgcgagt
    24001 gattaaactc atacattaac gtttttccac gaagtctttt ttcaggtaag ccttcgcaca
    24061 tatcggtaaa tagcttgcct gcttttattc tttctgtcat cgacatgttc attgcgatca
    24121 ttccgccctg atatgttggt cggataaggc gctcgcgccg catccgacat tgattgctta
    24181 agcgacttca ttcacctgac gacgcagtag agaaagcggg ccggggccgc taagcgtgaa
    24241 cacggaaatt aaggtgaagc ccagcgccac cagacccagc accagataag cgccctggaa
    24301 accgatgctt tcatacatat tgcccgccag tacagacata aaaatcatcg ccagttgctt
    24361 aaagaagcag aaacagacca gataaatcgt cgctgaaaaa cgcacttcaa actggctggt
    24421 aatatattta aagcagccca ccagcaggaa cggtacttca aacatatgca gcgttttcag
    24481 aataaccact tccagcgctg aggtggcgaa cgatgagcca ataatacgta cagacataat
    24541 agtgccagcc accagcaggg catttttccc accgatgcga ttaatgatca gtggcgcaaa
    24601 gaacataatc gaggcattaa gtaattcgcc cattgtcgtt acgtagccaa atacccgcgt
    24661 accctgttca ccggtagcaa aaaacgaagt aaagaaatta gcaaactgtt ggtcaaaaac
    24721 atcgtaggtg caggaaacgc caataacata cagtgacaaa aaccacagtt ttggctgtct
    24781 gaacagttcc agcgccagct taaggctaaa tgccgaatgg ttggcaccta ccgcattggc
    24841 aaccgtggct gaagagggcg catccgtttt ggcgaaaaag agtaaaacgg cgaggatgag
    24901 tgcacagcca gaacccagcc agaaaacaaa ctgattattg atggtgaaca tgatgccgac
    24961 aatcgaggca cacagcgccc agccaacaca gccaaacatc cgcgcgcgac caaattcgaa
    25021 atgactgcga cggctgactt tctcgataaa tgcctctact gctggcgcac cggcgttaaa
    25081 acaaaagcca agataaatac caccaacaat cgatcctact aaaatgttgt attgtaacag
    25141 tggtccgaag ataaaaataa agaacggcgc aaacatcact aacatgccgg taataatcca
    25201 cagcaggtat ttgcgcagcc cgagtttgtc agaaagcaga ccaaacagcg gttggaataa
    25261 tagcgagaac agagaaatag cggcaaaaat aatacccgta tcacttttgc tgatatggtt
    25321 gatgtcatgt agccaaatcg ggaaaaacgg gaagtaggct cccatgataa aaaagtaaaa
    25381 gaaaaagaat aaaccgaaca tccaaaagtt tgtgtttttt aaatagtaca taatggattt
    25441 ccttacgcga aatacgggca gacatggcct gcccggttat tattattttt gacaccagac
    25501 caactggtaa tggtagcgac cggcgctcag ctggaattcc gccgatactg acgggctcca
    25561 ggagtcgtcg ccaccaatcc ccatatggaa accgtcgata ttcagccatg tgccttcttc
    25621 cgcgtgcagc agatggcgat ggctggtttc catcagttgt tgttggctgt agcggctgat
    25681 gttgaactgg aagtcgccgc gccactggtg tgggccataa ttcaattcgc gcgtcccgca
    25741 gcgcagaccg ttttcgctcg ggaagacgta cggggtatac atgtctgaca atggcagatc
    25801 ccagcggtta aaacaggctg cagtaaggcg gtcgggatag ttttcttgcg gccccaggcc
    25861 gagccagttt acccgctctg cgacctgcgc cagctggcag gtcaggccaa tccgcgccgg
    25921 atgcggtgta tcgctcgcta cttcaacacc tacactgacg accatctcgc cgtgtccatc
    25981 aatccggtag gttttccggc tgataaataa ggttttcccc tgatgctgcc acgcgtgggc
    26041 ggtcgtaatc agcaccgcgt cggcaagtgt atctgccgtg cactgcaaca acgccgcttc
    26101 ggcctggtaa tggccagccg ccttccagcg ttcgacccag gcgttagggt caatgcgggt
    26161 cgcttcactt acgccaatgt cgttatccag cggcgcacgg gtgaactgat cgcgcagcgg
    26221 ggtcagcagt tgtttttcat cgccaatcca catctgtgaa agaaagcctg actggcggtt
    26281 aaattgccaa cgcttattac ccagctcgat gcaaaaatcc gtttcgctgg tggtcagttg
    26341 agggatggcg tgggacgcgg aggggagtgt cacgctgagg ttttccgcca gacgccattg
    26401 ctgccaggcg ctgatgtgtc cggcttctga ccatgcggtc gcgtttggtt gcactacgcg
    26461 taccgttagc cagagttgtc cggcgctctc cggctgcggc agttcaggca gttcaatcaa
    26521 ctgcttacct tgcgggccaa catccagagg cacttcaccg cttgccagcg gcttgccatc
    26581 cagcgccacc atccagtgca ggaactcgtt atcgctatga cggaacaggt attcgctggt
    26641 cacttcgatg gttcgcccgg ataaacggaa ctggaaatac tgctgttggt gttttgcttc
    26701 cgtcagcgcc ggatgcggcg tgcggtcggc aaagaccaga ccgttcatac agaactggcg
    26761 atcgttcggc gtatcgccaa aatcaccgcc gtaagccgac cacgggttgc cgttttcatc
    26821 atatttaatc agcgactgat ccacccagtc ccagacgaag ccgccctgta aacgggggta
    26881 ctgacgaaac gcctgccagt atttagcgaa gccgccaaga ctgttaccca tcgcgtgggc
    26941 atattcgcaa aggatcagcg ggcgcatttc tccaggcagc gaaagccatt ttttgatgga
    27001 ccatttcggc accgccggga agggctggtc ttcatccacg cgcgcgtaca tcgggcaaat
    27061 aatatcggtt gcggaggtgt cggctccgcc gccttcatac tgtaccgggc gggaaggatc
    27121 gacagatttg atccagcgat agagtgcgtc gtgattagcg ccgtggcctg actcattccc
    27181 cagcgaccag atgatcacac tcgggtgatt acgatcgcgc tgcaccatcc gcgttacgcg
    27241 ttcgctcatc gcgggtagcc agcgcggatc atcggtcaga cgattcattg gcaccatgcc
    27301 gtgggtttca atattggctt catccaccac atacaggccg taacggtcgc acagcgtgta
    27361 ccacagcgga tggttcggat aatgcgaaca gcgcacggca ttaaagttgt tctgcttcat
    27421 cagcaggata tcctgcacca tcgtctgctc atccatgacc tgaccatgca gaggatgatg
    27481 ctcgtgacgg ttaacgccgc gaatcagcaa cggcttgccg ttcagcagca gcagaccatt
    27541 ttcaatccgc acctcgagga aaccgacatc gcaggcttct gcttcaatca gcgtgccgtc
    27601 ggcggtgtgc agtttaacca ccgcacgata gagattcggg atttcggcgc tccacagttc
    27661 cggattttca acgttcaggc gtagcgtgac gcgatcggca taaccgccac gctcatcgat
    27721 aatttcaccg ccgaaaggcg cggtgccgct ggcgacctgc gtttcaccct gccacaaaga
    27781 aaccgtcacc cgcagttcat cgcgcagctc gccgtacatc tgaacttctg cctccagtac
    27841 cgcgcggctg aaatcatcat taaagcgagt ggtaacttgg aaatcgctga tttgcgtggt
    27901 cggtttatgc agcaacgaga cgtcacggaa aatgccgctc atccgccaca tatcctgatc
    27961 ttccagataa ctgccgtcac tccagcgcag caccatcacc gcgaggcggt tttctccggc
    28021 gcgtaaaaat gcgctcaggt caaattcaga cggcaaacgg ctgtcctggc cgtaaccgac
    28081 ccagcgcccg ttgcaccaca gatgaaacgc cgagttaacg ccatcaaaaa taattcgcgt
    28141 ctggccttcc tgtagccagc tttcatcaac attaaatgtg agcgagtaac aacctgtcgg
    28201 attctccgcg ggaacaaacg gcggattgac cgtaatggga taggttacgt tggtgtagat
    28261 gggcgcgtcg taaccgtgca tctgccagtt tgaggggacg acgacagtat cggcgtcagg
    28321 aagatcgcac tccagccagc tttccggcac cgcttctggt gccggaaacc aggcaaagcg
    28381 ccattcgcca ttcaggctgc gcaactgttg ggaagggcga tcggtgcggg cctcttcgct
    28441 atttcgccag ctggcgaaag ggggatgtgc cgcaaggcga ttaagttgtg taacgccagg
    28501 gttttcccag tcacgacgtt gtaatacgac ggccagagaa tccgtaatca tagtcatagc
    28561 tgtatcctgt gtgaaattgt tatccgctca caatttcaca caacatacga gccggacaca
    28621 tagagtgtaa agactggggt gcctaatgag tgagctgact cacattaatt gtgttgcgct
    28681 cactgcccgc tttccagtcg ggaaacttgt cgtgccagct gcattaatga atcggccaac
    28741 gcgcggggag aggcggtttg cgtattgggc ggaagggtgg tttttctttt caccagtgag
    28801 acgggcaaca gctgattgcc cttcaccgcc tggccctgag agagttgcag caagcggtcc
    28861 acgctggttt gccccagcag gcgaaaatcc tgtttgatgg tggttaacgg cgggatataa
    28921 cacgagctgt cttcggtatc gtcgtatccc actaccgaga tatccgcacc aacgcgcagc
    28981 ccggactcgg taatggcgcg cattgcgccc agcgccatct gatcgttggc aaccagcatc
    29041 gcagtgggaa cgatgccctc atttagcatt tgcatggttt gttgaaaacc ggacatggca
    29101 ctccagtcgc cttcccgttc tgttatcggc tgaatttgat tgcgtgtgag atatttatgc
    29161 cagcccgcca gacgcagacg cgccgagaca gaacttaatg ggcctgctaa cagcgcgatt
    29221 tgctggtgac ccaatgcgac caggtgctcc acgcccagtc gcgtaccgtc ttcatgggag
    29281 aaaataatac tgttgatggg agtctggtca gagacatcaa gaaataacgc cggaacatta
    29341 gcgcaggcag cttccacagc aatggcatcc tggtcatcca gcggatagtt aatgatcagc
    29401 ccactgacgc gttgcgcgag aagattgtgc accgccgctt tacaggcttc gacgccgctt
    29461 cgttctacca tcgacaccac cacgctggca cccagttgat cggcgcgaga ttttatcgcc
    29521 gcaacaattt gcgacggcgc gtgcagggcc agactggaag tggcaacgcc aatcagcaac
    29581 gactgtttgc ccgccagttg ttgtgccacg cggttgggaa tgtaattcag ctccgccatc
    29641 gccgcttcca ctttttcccg cgttttcgct gaaacgtggc aggcctggtt caccacgcgg
    29701 gaaacggtct gataagagac accggcatac tctgcgacat cgtatagcgt tactggtttc
    29761 acattcacca ccctgaattg actctcttcc gggcgctatc atgccatacc acgaaaggtt
    29821 ttgcgccatt cgatggtgtc agcgtaaatg cacgccgctt cgccttcccg ctaccagaat
    29881 agcctgcgat tcaacccctt cttcgatctg ttttgccacc cgttgcagcg ccggaagatg
    29941 cttttccgct gcctgttcga tggtcattgc gctcgccata tacaccagat tcagacagcc
    30001 aatcacccgt tgttcactgc gcagcggtac ggcgatagag gcgatcttct cctcctgatc
    30061 ccagccgcgg tagttctgtc cgtacccctc tttgcgcgcg cgcgccagaa tggcttccag
    30121 ctttaacggt tctcgtgcca gttgatagtc atcaccgggg cgggaggcta acatctcgat
    30181 taattccttg cgttcttgtt ccgggcaaaa ggccagccag gtcaggcccg aggcggtttt
    30241 cagaagcggt aaccgtcgcc cgaccattgc ccggtgaaaa gataagcggc tgaaacgatg
    30301 ggtggtttcg cgtaccacca ttgcatcaac atccagcgtg gacacatctg tcggccatac
    30361 cacttcgcgc aacagatcgc ccagcagcgg ggccgccagt gcagaaatcc actgttcgtc
    30421 acgaaatcct tcgcttaatt gccgcacttt gatggtcaga cgaaaactgt catcggaggt
    30481 actgcgccgg acatatccct cttccagtaa cgtctccagc agtcgccgca cagtggtgcg
    30541 atgcaggccg ctgagttccg ccagcagccc gacgctggca ccgccatcaa gtttatttaa
    30601 catatttaat aacattagac cgcgggttaa gccgcgcacg gttttgtatt ccgtctgctc
    30661 attgttctgc atattaattg acatttatat agttaaaaca acgttgtgca cctggtgcac
    30721 attcgggcat gttttgattg tagccgaaaa cacccttcct atactgagcg cacaataaaa
    30781 aatcatttac atgtttttaa caaaataagt tgcgctgtac tgtgcgcgca acggcatttt
    30841 gtccgagtcg tgaggtactg aaatggcaat acaacaccct gacatccagc ctgctgttaa
    30901 ccatagcgtt caggtggcga tcgctggtgc cggtccggtc gggctgatga tggcgaacta
    30961 tctcggccag atgggcattg acgtgctggt ggtggagaaa ctcgataagt tgatcgacta
    31021 cccgcgtgcg attggtattg atgacgaggc gctgcgcacc atgcagtcgg ttggcctggt
    31081 cgataatgtt ctgccgcaca ctacgccgtg gcacgcgatg cgttttctca ccccaaaagg
    31141 tcgctgtttt gctgatattc agccaatgac cgatgaattt ggctggccgc gccgtaacgc
    31201 ctttattcag cctcaggtcg atgcggtgat gctggaagga ttgtcgcgtt ttccgaatgt
    31261 gcgctgcctg ttttcccgcg agctggaggc cttcagccag caagatgacg aagtgacctt
    31321 gcacctgaaa acggaagaag ggcagcggga aacggtcaaa gcccagtggc tggtggcctg
    31381 tgatggtggg gcaagttttg tccgtcgcac cctgaatgtg ccgtttgaag gtaaaactgc
    31441 gccaaatcag tggattgtgg tagatatcgc caacgatccg ttaagtacgc cgcatatcta
    31501 tttgtgttgt gatccggtgc gcccgtatgt ttctgccgcg ctgcctcatg cggtacgtcg
    31561 ctttgaattt atggtgatgc cgggagaaac cgaagaacag ctgcgtgagc cgcaaaatat
    31621 gcgcaagctg ttaagcaaag tgctgcctaa tccggacaat gttgaattga ttcgccagcg
    31681 tgtctacacc cacaacgcgc gactggcgca acgttttcgt attgatcgcg tactgctggc
    31741 gggcgatgcc gcgcacatca tgccggtgtg gcaggggcag ggctataaca gtggtatgcg
    31801 cgacgccttt aacctcgcat ggaaactggc gttggttatc caggggaaag cccgcgatgc
    31861 gctgctcgat acctatcaac aagaacgtcg cgatcacgcc aaagcgatga ttgacctgtc
    31921 cgtgacggcg ggcaacgtgc tggctccgcc gaaacgctgg cagggtacgt tacgtgacgg
    31981 cgtttcctgg ctgctgaatt atctgccgcc agtaaaacgc tacttcctcg aaatgcgctt
    32041 caagccgatg ccgcaatatt acggcggtgc gctggtgcgt gagggcgaag cgaagcactc
    32101 tccggtcggc aagatgttta ttcagccgaa agtcacgctg gaaaacggcg acgtgacgct
    32161 actcgataac gcgatcggcg cgaacttcgc ggtaattggc tggggatgca atccactgtg
    32221 ggggatgagc gacgagcaaa tccagcagtg gcgcgcgttg ggcacacgct tcattcaggt
    32281 ggtgccggaa gtgcaaattc ataccgcaca ggataaccac gacggcgtac tacgcgtggg
    32341 ggatacgcaa ggtcgcctgc gtagctggtt cgcgcaacac aatgcttcgc tggtggtgat
    32401 gcgcccggat cgctttgttg ccgccaccgc cattccgcaa accctgggca agaccctgaa
    32461 taaactggcg tcggtgatga cgctgacccg ccctgatgcc gacgtttctg tcgaaaaggt
    32521 agcctgatat gcacgcttat cttcactgtc tttcccactc gccgctggtg gggtatgtcg
    32581 acccggcaca agaggtactc gatgaggtca atggcgtgat tgccagcgcc cgcgagcgta
    32641 ttgcggcttt ctcccctgaa ctggtggtgc tgtttgcgcc agatcactac aacggctttt
    32701 tctatgacgt gatgccaccg ttctgtttag gcgttggagc gacggcaatt ggtgatttcg
    32761 gcagtgcggc aggagagctg cccgtgcctg tggagctggc ggaggcctgt gcgcatgccg
    32821 tcatgaagag cgggatcgat cttgccgttt cttactgtat gcaggtggac cacgggttcg
    32881 cccagccgct ggagttcctg ctcggtgggc tggataaggt gccagtactg ccggtgttca
    32941 tcaacggtgt cgccacgccg ctgcccggtt tccagcgtac ccgcatgttg ggggaagcca
    33001 ttggacgttt caccagtact ctcaataaac gcgtgctgtt cctgggttcc ggtgggcttt
    33061 cccatcagcc gccggtgccc gaactggcga aagccgatgc ccatatgcgc gaccgtctgt
    33121 tggggagcgg gaaagattta cccgccagtg agcgcgaatt gcgtcagcaa cgggtgatta
    33181 gcgccgctga gaagtttgtt gaggatcaga gaacgctgca tccgctcaac ccgatttggg
    33241 ataaccagtt catgactttg ctggagcagg gacgcataca ggaactggat gccgtcagta
    33301 acgaagagct ttccgccatt gccggaaagt cgacacatga aatcaaaacc tgggtcgccg
    33361 cttttgccgc tatttctgcg tttggcaact ggcgtagcga agggcgttat taccgcccaa
    33421 tcccggagtg gattgccgga tttggctcgt taagcgccag aacagagaac tgaatatgca
    33481 ggagaagatg atgagttatc agccacaaac cgaagccgcc accagccgtt ttctgaatgt
    33541 agaagaagcg ggtaaaacgc tgcgcatcca ttttaatgac tgcggacaag gcgacgaaac
    33601 cgttgtcctg ctgcatggtt ccggcccggg tgctactggc tgggcgaact tcagccgcaa
    33661 tatcgatccg ctggtagagg cgggctatcg ggtgatcctg ctggattgtc cgggttgggg
    33721 taagagcgat tcgatcgtta atagtggttc gcgatcggat cttaatgcgc gaatcctgaa
    33781 aagcgtggtg gatcaactgg atatcgccaa aatccacctg ctgggcaact cgatgggtgg
    33841 ccacagttct gtggcgttca ctcttaactg gccggagcgc gtcggcaaac tggtgctgat
    33901 gggcggcggt acgggcggca tgagtttgtt tacgccgatg ccaaccgaag gtattaagcg
    33961 actgaatcag ctttatcgtc agccgactat cgaaaacctg aagctgatga tggatatctt
    34021 cgtttttgat accagcgatt tgaccgacgc cctgtttgaa gcgcgcctga ataatatgct
    34081 gtcgcgccgc gatcacctgg aaaacttcgt taagagcctg gaagccaatc cgaaacagtt
    34141 cccggatttt ggcccacgtc tggcggaaat caaagcgcaa accctgattg tctgggggcg
    34201 caacgaccgc tttgtgccga tggatgcggg tctgcgtctg ctgtccggca ttgccggttc
    34261 tgaactgcat atcttccgcg actgtggtca ctgggcgcag tgggaacatg ccgacgcttt
    34321 caatcaactg gtgctgaatt tcctcgcacg cccttaagga acggtcatga cgaagcatac
    34381 tcttgagcaa ctggcggcgg atttacgccg cgccgcagag cagggcgaag cgattgcgcc
    34441 gctgcgcgat ctgattggta tcgataacgc tgaagcggcc tacgccattc agcacatcaa
    34501 tgtgcaacat gacgttgcgc aggggcgtcg cgtggtgggg cgcaaagtgg ggctgacgca
    34561 tccgaaagtg cagcaacaac tgggcgttga tcaaccggat ttcgggacat tatttgccga
    34621 catgtgttat ggcgataatg aaaccattcc tttttcccgt gttctgcaac cccgcattga
    34681 agcggagatt gcactggtgt tgaaccgcga tctacccgca accgatatca ccttcgacga
    34741 attgtataac gccattgaat gggtacttcc ggcgctggag gtggtgggga gccgcattcg
    34801 cgactggtcg attcagtttg tcgataccgt ggcagataac gcttcctgcg gggtgtatgt
    34861 catcggcggt ccggcgcaac gcccggcggg gttagacctg aaaaactgcg ccatgaagat
    34921 gacgcgtaat aacgaagagg tttccagcgg gcgcggcagc gaatgcctgg gacatccgct
    34981 taatgccgcc gtctggctgg cacgcaaaat ggccagtctg ggtgaaccgc tgcgcgccgg
    35041 agatatcatt cttaccgggg cattaggtcc gatggtggcg gtgaatgcgg gcgatcgttt
    35101 tgaagcccat atcgaaggca taggttcagt tgctgcgaca ttttcaagcg cagccccaaa
    35161 aggaagtctg tcatgagtaa gcgtaaagtc gccattatcg gttcaggcaa cattggcacc
    35221 gatctgatga ttaaaatttt gcgtcacggt cagcatctgg agatggcggt gatggtcggc
    35281 attgatcctc agtccgacgg tctggcgcgt gccagacgta tgggcgtcgc caccacccat
    35341 gaaggggtga tcgggctgat gaacatgcct gaatttgctg atatcgacat tgtatttgat
    35401 gcgaccagcg cgggcgcgca tgtgaaaaac gatgccgctt tgcgcgaagc gaaaccggat
    35461 attcgcttaa ttgacctgac gcctgctgcc atcggccctt actgcgtgcc ggtggttaac
    35521 ctcgaggaga acgtcgctca actgaacgtc aacatggtca cctgcggcgg ccaggccacc
    35581 attccaatgg tagcggcagt ttcacgcgtg gcgcgtgttc attacgccga aattatcgct
    35641 tctattgcca gtaaatctgc cggacccggc acgcgtgcca acatcgatga atttacggaa
    35701 accacttcgc gcgccattga agtggtgggt ggcgcggcaa aagggaaggc gattattgtg
    35761 cttaacccag cagagccacc gttgatgatg cgtgacacgg tgtatgtatt gagcgacgaa
    35821 gcttcacaag atgatatcga agcctcaatc aatgaaatgg ctgaggcggt gcaggcttac
    35881 gtaccgggtt atcgcctgaa acagcgcgtg cagtttgaag tcatcccgca ggataaaccg
    35941 gtcaatttac cgggcgtggg gcagttctcc gggctgaaaa cggcggtctg gctggaagtc
    36001 gaaggcgcag cgcattatct gcctgcctat gcgggcaacc tcgacattat gacttccagt
    36061 gcgctggcga cagcggaaaa aatggcccag tcactggcgc gcaaggcagg agaagcggca
    36121 tgaacggtaa aaaactttat atttcggacg tcacgttgcg tgacggtatg cacgccattc
    36181 gtcatcagta ttcgctggaa aatgtccgcc agattgccaa agcactggat gatgcccgcg
    36241 tggattcgat tgaagtggcc cacggcgacg gtttgcaggg ttccagcttt aactatggtt
    36301 tcggcgcaca tagcgacctt gaatggattg aagcggcggc ggatgtggtg aagcacgcca
    36361 aaatcgcgac gttgttgctg ccaggaatcg gcactattca cgatctgaaa aatgcctggc
    36421 aggctggcgc gcgggtggtt cgtgtggcaa cgcactgtac cgaggctgat gtttccgccc
    36481 agcatattca gtatgcccgc gagctcggaa tggacaccgt tggttttctg atgatgagcc
    36541 atatgaccac gccggagaat ctcgcaaagc aggcaaagct gatggaaggc tacggtgcga
    36601 cctgtattta tgtggtggat tctggcggtg cgatgaacat gagcgatatc cgtgaccgtt
    36661 tccgcgccct gaaagcagtg ctgaaaccag aaacgcaaac cggcatgcac gctcaccata
    36721 acctgagtct tggcgtggcg aattctatcg cggcggtgga agagggctgc gaccgaatcg
    36781 acgccagcct cgcgggaatg ggcgcgggcg caggtaacgc gccgctggaa gtatttattg
    36841 ccgccgcgga taaactgggt tggcagcatg ggggcgatct ctatgcgtta atggatgccg
    36901 ctgacgacct ggtgcgtccg ttgcaggatc gaccggtacg agtcgatcgc gaaacgctgg
    36961 cgctgggata cgctggtgtt tactccagct tcctgcgtca ctgtgaaacg gcggcggcgc
    37021 gttatggctt aagcgcggtg gatattctcg ttgagctggg caaacgccgg atggttggcg
    37081 gccaggagga tatgatcgtc gacgtggcgc tggatctgcg caacaacaaa taatattgac
    37141 tgccgagaac gtgcattttg tatgcccatc ccagcacgac tgccggatgc ggcgtgaacg
    37201 ccttatccgg cctacatttc gcccgtaggc agtcattaaa tagttctgat tacgcggctg
    37261 gcaatgtatc agtcgcgatt cacctgcact cgcaatgagg ttcatcttat gtcgactcgt
    37321 accccttcat catcttcatc ccgcctgatg ctgaccatcg ggctttgttt tttggtcgct
    37381 ctgatggaag ggctggatct tcaggcggct ggcattgcgg cgggtggcat cgcccaggct
    37441 ttcgcactcg ataaaatgca aatgggctgg atatttagcg ccggaatact cggtttgcta
    37501 cccggcgcgc tggttggcgg gatgctggca gaccgttatg ggcgtaagcg tattttgatt
    37561 ggctcagttg cgctgtttgg tttgttctcg ctggcaacgg cgattgcatg ggatttcccc
    37621 tcactggtct ttgcgcggct gatgaccggt gtcgggctgg gggcggcgtt gccgaatctt
    37681 atcgccctga cgtctgaagc cgcgggacca cgttttcgtg ggacggcagt gagcctgatg
    37741 tattgcggtg ttcccattgg cgcggcgctg gcggcgacgc tgggtttcgc gggggcaaac
    37801 ttagcatggc aaacggtgtt ttgggtaggt ggtgtggtgc cgttgattct ggtgccgcta
    37861 ttaatgcgct ggctgccgga gtcgacggtt ttcgctggcg aaaaacaggc tgcgccacca
    37921 ctgcgtgcgt tatttgcgcc agaaacggca accgcgacgc tgctgctgtg gttgtgttat
    37981 tttttcactc tgctggtggt ctacatgttg atcaactggc tgccgctgct tttggtggag
    38041 caaggattcc agccatcgca ggcggcaggg gtgatgtttg cactgcaaat gggggcggca
    38101 agcgggacgt taatgttggg cgcattgatg gataaactgc gtccagtaac catgtcgcta
    38161 ctgatttata gcggcatgtt agcttcgctg ctggcgctgg gaacggtgtc gtcatttaac
    38221 agtatgttgc tggcgggatt tgtcgcgggg ttgtttgcga caggtgggca aagcgttttg
    38281 tatgctctgg caccgttgtt ttacagttcg cagatccgcg caacaggtgt gggaacagcc
    38341 gtggcggtag ggcgtctggg ggctatgagc ggtccgttac tggccgggaa aatgctggca
    38401 ttaggcactg gcacggtcgg cgtaatggcc gcttctgcac cgggtattct tgttgctggg
    38461 ttggcggtgt ttattttgat gagtcggaga tcaagaatgc agccgtgtgc cgatgcctga
    38521 cgcgccttat taagcagggg cgaaagggac ttgcccccaa tacacctacg gcgtttacag
    38581 gtatactcgc taaaaattat tcagcgggtt tggaaacaaa gatggcaaaa cttaccttac
    38641 aagagcagtt gctcaaagcg ggactagtca ccagcaaaaa agcggcgaag gtcgagagaa
    38701 cggcgaaaaa atcgcgtgtt caggcgcgtg aagcacgggc ggcggtagaa gaaaataaaa
    38761 aggcacagct tgagcgtgat aaacagctta gcgagcaaca aaaacaagcg gcgttggcga
    38821 aagaatataa agcccaggtg aagcagctca ttgaaatgaa ccgaattacc attgccaatg
    38881 gcgatattgg ttttaacttc actgacggca atctgattaa gaagattttt gtcgataagc
    38941 tcacgcaaac gcagttgatt aatggtcgtc tggcgattgc ccgcttgttg gtcgataaca
    39001 atagcgaagg tgaatacgcc attattcccg ccagcgttgc cgataaaatt gctcagcgtg
    39061 atgccagcag tattgtgttg cacagcgcgc tcagcgccga agagcaggat gaagacgatc
    39121 cgtatgccga cttcaaagtg cctgatgatt tgatgtggta aacattgata aatcgtgtgc
    39181 agatgcctga tgcgacgctt ttcgcgtctt atcaggccta cggtttacga gcgaaatgtg
    39241 ggccggataa ggtttacgcc gcatccggca tgcgtgcgcg gatgctcaac gcatattcag
    39301 tttattggcg tggtaggcaa tatgctcgcc aataaaactg gagacaaaat aatagctgtg
    39361 atcataaccc tcgtgataac ggattaacgt cttgatattc atctcctggc agatcttttc
    39421 aagatttgga gtccgcagtt gttccgcgta aaaatcatca ctcaacccct gatcaaccat
    39481 gatttccgca acgcgttgac cttgtgaaat aagactcacc ggatcgtaat ccaaccaggc
    39541 atctttattt tcaccaagat atgcggcaaa ggcttgctgt ccccacggta cttgcgatgg
    39601 ggagacaatg ggcgaaaacg ccgagacgct gacatattca tctgggttac gtaacgccag
    39661 caccagcgcg cccagcccgc ccatagaatg acctgcgatt gactttctgg ccgttgccgg
    39721 aaaatgatgc atcactaaat tcggcagctc gttgcggata tagtcataca ttttgtaatg
    39781 ttcattccac ggcgcttgcg tcgcgttcag gtaaaacccg gcaccttgcc cgagatcgta
    39841 acggtcagca tctgcgacat gactgcctcg cggactggtg tccggcgcaa caacaataat
    39901 gttgtgctca gccgcgtaac gctgcatccc cgatttagta atgaaatttt gctcgttgca
    39961 ggtcaggcct gaaagccagt acaacaccgg caatttttca ttctcggctt ttggggggag
    40021 atagacgccg acattcattt cacatttcag tgattgggaa taatgccgat acacattttg
    40081 ccagccgcca aagctggcat gtttttcaat gagttccatc agtcattatc tcacggttaa
    40141 tcccccggac ggctgcccgg ggagagtatt aagaacccca tctgaactgg acggggtaaa
    40201 ccagcgggaa atcagtaacg aattacggtt cgaatggatt taccttcatg catcaggtcg
    40261 aaggcgtcat taatttcatc caggctcatg gtatgcgtga caaacggttc cagatcgata
    40321 tcacctttca tcgcatcttc aaccataccc ggtaactggg aacgaccttt cacgccgcca
    40381 aacgcggaac ctttccatac gcgaccggtg accaactgga atggacgggt ggagatttcc
    40441 tgaccggagc ctgctacccc gatgatcacc gactgacccc agccgcggtg cgcgctttcc
    40501 agcgctgcac gcatcacgtt gacgttaccg atgcattcaa aggtatggtc gataccccat
    40561 ttgttgatat ccagcaggac atctttaatc ggtttgtcgt agtcattcgg gttaatgcag
    40621 tcggtggcac cgaagcgacg cgccagttcg aatttcttcg ggttggtatc gatagcgata
    40681 atccgtcccg cttttgcctg acgcgcgccc tgaaccactg ccagaccaat cgcgccaaga
    40741 ccaaacacgg caacagaatc acctggctgg actttagctg tgttgtgtac cgcgccaata
    40801 ccggtggtca cgccacagcc cagcaggcag acgtgttcat ggtttgcttc tggattaatt
    40861 ttggccagag acacttccgc taccacggtg tattcactga atgttgagca tcccatgtag
    40921 tgataaagcg gctgcccgtt gtaagaaaaa cgggtggtgc cgtctggcat caagcctttg
    40981 ccctgcgttt cgcgaaccgc gacacacagg ttggttttgc cagaacgaca aaactcacac
    41041 tcgccgcact ctgcggtgta aagtgggatc acatggtcgc caggtttgac gctggttacg
    41101 ccttcaccga cttcaactac aaccccggcc ccttcgtgac cgagaaccac tgggaagaca
    41161 ccttccgggt catcgccgga gagggtaaat gcgtcggtat ggcaaacacc ggtatgggtg
    41221 actttaatca gcacttcacc ttttttcggt ggtgcaacgt caatttcaac gatttccagc
    41281 ggtttaccgg gagcaaatgc aacggcagca cgtgatttca tctctcgctc ttcctcaata
    41341 tggtaataga ttcagctatt taagataggc acgaaccagt tcaatagtgt cgtcaacgga
    41401 ttggctgact tcacggctgt agcagtcatt tcggtcaaac gtttcccgga tatggctttc
    41461 aagcacttct gccatcagtc cgttagccgc gccccgaacg gcagcgatct gttggagtat
    41521 ggcacggcat tcggcatcac cctccagcga ccgttccaga gcatcaatct gcccccgaat
    41581 acgacgaact cgagtaagga cctttttctt ctcttccgga gtactgggca tttcgcacct
    41641 catcatctgc acgcaatata ctataggggg gtatgctata tgtcaatgca taccccccta
    41701 tagtatataa cactggagaa taaaatttat ccggccccag tatttgtagg catgataaga
    41761 ggcgtgagcg tcacatcagg cgatgtttgt taaaagtagc aaaatgcgca aactcgctaa
    41821 ccattgccga tttttttcta aaaacgcttt gttattaaca agacgtttta attcctttat
    41881 caaacttacc cgcaacgaaa tactgctccc ataacaagac gggggagcag acaatcatgg
    41941 caatttcatc gcgtaacaca tttcttgccg cactggcatt catcgctttt caggcgcaag
    42001 cggtgaacgt caccgtggcg tatcaaacct ccgccgaacc ggcgaaagtg gctcaggccg
    42061 acaacacctt tgctaaagaa agcggagcaa ccgtggactg gcgtaagttt gacagtggag
    42121 ccagcatcgt gcgggcgctg gcttcgggcg atgtgcaaat cggcaacctc ggttccagcc
    42181 cgttagcggt tgcaaccagc caacaggtgc cgattgaagt cttcttgctg gcgtcaaaac
    42241 tgggtaactc cgaagcgctg gtggtaaaga aaactatcag taaaccggaa gacttgattg
    42301 gtaaacgcat cgccgtaccg tttatctcca ccacccacta cagcctgctg gcggcgctga
    42361 aacactgggg tattaaacct gggcaagttg agattgtgaa cctgcagccg cccgcaatta
    42421 tcgccgcatg gcagcgggga gatattgatg gtgcttatgt atgggcaccg gcggttaacg
    42481 ccctggaaaa agatggcaag gtgctgaccg attctgaaca ggtcgggcag tggggcgcgc
    42541 cgacactgga cgtctgggtc gtgcggaaag attttgccga gaaacatcct gaggtcgtga
    42601 aagcgttcgc taaaagcgcc atcgatgctc agcaaccgta cattgctaac ccagacgcgt
    42661 ggctgaaaca gccggaaaac atcagcaaac tggcgcggtt aagcggcgtg ccggaaggtg
    42721 acgttccggg gctggtgaag gggaatacct atctgacgcc gcagcaacaa acggcagaac
    42781 tgaccggacc ggtgaacaaa gcgatcatcg acaccgcgca gtttttgaaa gagcagggca
    42841 aagtcccggc tgtagcgaat gattacagcc agtacgttac ctcgcgcttc gtgcaataaa
    42901 aggaggcgca gatgctgcaa atttctcatc tttacgccga ttatggcggc aaaccggcac
    42961 tggaagatat caacctgacg ctggaaagcg gcgagcttct ggtagttctg gggccgtctg
    43021 gctgcggcaa aactacgttg ctgaatttga ttgctggttt tgtgccttat cagcatggca
    43081 gcattcaact ggcgggtaag ggtattcagg gaccgggagc agagcgtggc gtagtttttc
    43141 agaatgaagg gttgttaccg tggcgcaatg tacaggacaa cgtggcgttc ggcctgcaac
    43201 tggcaggtgt agagaaaatg cagcgactgg aaatcgcaca ccagatggtg aaaaaagtcg
    43261 ggctggaagg cgcagaaaaa cgctacatct ggcagctttc cggtggtcaa cgtcagcggg
    43321 tggggattgc ccgcgcgttg gcggcaaatc cccagctgtt attactcgac gaaccgtttg
    43381 gtgcgctgga cgccttcacc cgcgaccaga tgcaaaccct gctgctgaaa ctttggcagg
    43441 agacgggaaa gcaggtgctg ttgattaccc acgatataga agaagcggtg tttatggcga
    43501 ctgaactggt tttgctttca cccggcccag gccgtgtgct ggagcggctg ccgctcaact
    43561 ttgctcgccg ctttgttgcg ggagagtcga gccgcagcat caagtccgat ccacaattca
    43621 tcgccatgcg cgaatatgtt ttaagccgcg tatttgagca acgggaggcg ttctcatgag
    43681 tgtgctcatt aatgaaatac tgcattcgca tcggctgaaa tggcgctggc cgctctcgcg
    43741 tcaggtgacc ttaagcattg gtacgttagc ggttttgctc actgtatggt gggcagtcgc
    43801 ggcgctgcaa ctgattagcc cgctgttttt gccgccaccg caacaggtac tggcaaaact
    43861 gctcaccatt gccgggccgc agggatttat ggacgccacg ctgtggcagc atctggcagc
    43921 cagcctgacg cgcattttgc tggcgctact cgcggcggtg ttgatcggta ttccggtcgg
    43981 gatcgccatg gggctaagcc cgacggtgcg cggcattctg gatccgataa tcgagcttta
    44041 tcgtccggtg ccgccgctgg cttatttgcc gctgatggtg atctggtttg gtattggcga
    44101 aacctcgaag atcttgctga tctatttagc gatttttgcg ccggtggcga tgtcggcgct
    44161 ggcgggggtg aaaagcgcgc agcaggttcg cattcgtgcc gcccagtcgc tgggtgccag
    44221 ccgtgcgcag gtgctgtggt ttgtcatttt gcccggcgcg ctgccggaaa tcctcaccgg
    44281 attacgcatt ggtctgggtg tgggctggtc tacgctggtg gcggcggagc tgattgccgc
    44341 aacgcgcggt ttaggattta tggttcagtc agcgggtgaa tttctcgcga ctgacgtggt
    44401 gctggcgggg atcgcggtga ttgcgattat cgcctttctt ttagaactgg gtctgcgcgc
    44461 gttacagcgc cgcctgacgc cctggcatgg agaagtacaa tgagtgaacg tctgagcatt
    44521 accccgctgg ggccgtatat tggcgcacaa attacggggg ccgacttaac gcgcccgtta
    44581 agcgataatc agtttgaaca gctttaccat gcggtgctgc gccatcaggt ggtgtttctg
    44641 cgcgatcaag ctatcacgcc gcagcagcaa cgcgcgctgg cccagcgttt tggcgagctg
    44701 catattcacc ctgtttaccc tcatgctgaa ggggttgacg agatcatcgt cctggatacc
    44761 cataatgata atccgccgga taacgacaac tggcacaccg atgtgacatt tattcaaacg
    44821 ccacccgcag gggcgattct ggcggcgaaa gagttaccct cgaccggcgg cgatacgctc
    44881 tgggccagtg gtattgccgc atatgaggcg ctctctgttc ccttccgcca gctgttgagc
    44941 gggttgcgtg cggagcatga tttccgtaaa tcgttcccgg aatacaagta ccgcaaaacc
    45001 gaggctgagc atcaacgctg gcgtgaggcg gtcgcgaaaa atccaccgtt gctacatccg
    45061 gtggtgcgaa cgcatccggt gaccggtaaa caggcactgt ttgtgaacga aggttttacc
    45121 acacgaattg ttgatgtcag cgagaaagag agcgaagcct tgttaggttt tttgtttgcc
    45181 catatcacta aaccggagtt tcaggtgcgc tggcgctggc aaccgaatga tattgcgatt
    45241 tgggataacc gagtgactca gcactatgcc aatgcggatt acctgccaca gcggcggatt
    45301 atgcatcggg cgacgattct tggggatatt ccgttttatc gggcggggta agggggaaat
    45361 gccgggttgg ataacccggc ataatgatca ttaacgcaga atcttcttct cagccaaatc
    45421 cagcgcaaag tagctgaaaa tcagatccgc acccgcacgc ttaatcgaac ctaagctttc
    45481 gagcacgact ttctcttcat ctatagcacc cgccagcgcg gcgaacttaa tcatcgcgta
    45541 ctcaccgctc acctgatacg cgccaatcgg caattcagta cgttcacgca gctcacgcac
    45601 gatgtcgagg tatgctccgg caggtttaac catcaggcag tctgcgccct gggcttcatc
    45661 cagcagtgac tcacgaatcg cctcacgacg gttcattggg ttcatctgat agcttttgcg
    45721 gtcgcctttt aatgcgcttc cggcagcttc acggaacggg ccataaaagg aggaggcgaa
    45781 cttggtcgaa tacgacataa tcgccgtatc tttaaagccc gcagcgtcca gcgcctggcg
    45841 aatcgcctgt acctgaccat ccatcgcggc agaaggggcg atgaagtctg cgcctgcagc
    45901 agctgcaacc acggcttgct tgcctaaatt ttccagagtc gcgtcgttgt cgacgccatg
    45961 ctcgcacaga acaccgcagt gaccgtgaga tgtgtattca cagaagcagg tgtctgacat
    46021 aacgatcatt tctggcacgg tctgcttgca gatgcgcgac atacgcgcca ccagtccatc
    46081 ttcccgccag gcatcgctgc cggtttcatc ggtatggtga gagatgccga aagtcatcac
    46141 ggaacgaata ccggcgttgg cgatgcgttc aatttcgcgt gccagatgtt tctctggaat
    46201 gcgcatcacg cctggcatgg cttcaacggc tttatagtcg tcaatttctt cttcaacaaa
    46261 gatcggcaac accaggtcgt taaggctaag tgttgtctct tcaaacatag cgcgcagcgc
    46321 aggagatttg cgcaggcgac gagggcgttg gattaagtct gtcatggtct gcctgatgtt
    46381 t
//
LOCUS       DAFGPF010000026        46376 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFGPF010000026 DAFGPF010000000
VERSION     DAFGPF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46376
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.026"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            139..402
                     /gene="yhcN"
                     /locus_tag="LSX49_001680"
     CDS             139..402
                     /gene="yhcN"
                     /locus_tag="LSX49_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HBL7168105.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
     gene            complement(457..729)
                     /locus_tag="LSX49_001681"
     CDS             complement(457..729)
                     /locus_tag="LSX49_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HBL7168106.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(821..2788)
                     /gene="aaeB"
                     /locus_tag="LSX49_001682"
     CDS             complement(821..2788)
                     /gene="aaeB"
                     /locus_tag="LSX49_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HBL7168107.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPCMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVHRLTGMLHKYQHALTDS"
     gene            complement(2794..3726)
                     /gene="aaeA"
                     /locus_tag="LSX49_001683"
     CDS             complement(2794..3726)
                     /gene="aaeA"
                     /locus_tag="LSX49_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HBL7168108.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            complement(3734..3937)
                     /locus_tag="LSX49_001684"
     CDS             complement(3734..3937)
                     /locus_tag="LSX49_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HBL7168109.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            4120..5049
                     /gene="aaeR"
                     /locus_tag="LSX49_001685"
     CDS             4120..5049
                     /gene="aaeR"
                     /locus_tag="LSX49_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HBL7168110.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            complement(5171..6616)
                     /gene="tldD"
                     /locus_tag="LSX49_001686"
     CDS             complement(5171..6616)
                     /gene="tldD"
                     /locus_tag="LSX49_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HBL7168111.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVNNLTVGGTA"
     gene            complement(6772..10572)
                     /gene="yhdP"
                     /locus_tag="LSX49_001687"
     CDS             complement(6772..10572)
                     /gene="yhdP"
                     /locus_tag="LSX49_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HBL7168112.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTSITSGGGNDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKET
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWIPEQDVGGKDNKRS
                     DELRIRASNLELAGLEGVRPLVAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLNNDKGFQLDGRNIDVKAKAVHARGGFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINGDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPAAVNEALSGSVAWDGKVGIELPYHAGATYNVELNGDLKNV
                     SSHLPSPLAKPAGEPLSVNVKVDGNLNSFELTGQAGADNYFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTR
                     GDSTQSSPFPTTERISFRGWPDAQIRCAECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFARLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
     gene            complement(10640..12109)
                     /gene="rng"
                     /locus_tag="LSX49_001688"
     CDS             complement(10640..12109)
                     /gene="rng"
                     /locus_tag="LSX49_001688"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HBL7168113.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            complement(12099..12692)
                     /gene="yhdE"
                     /locus_tag="LSX49_001689"
     CDS             complement(12099..12692)
                     /gene="yhdE"
                     /locus_tag="LSX49_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HBL7168114.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV
                     RKINGSFHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            complement(12701..13189)
                     /gene="mreD"
                     /locus_tag="LSX49_001690"
     CDS             complement(12701..13189)
                     /gene="mreD"
                     /locus_tag="LSX49_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBL7168115.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            complement(13189..14292)
                     /gene="mreC"
                     /locus_tag="LSX49_001691"
     CDS             complement(13189..14292)
                     /gene="mreC"
                     /locus_tag="LSX49_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBL7168116.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGITQPTPQQPATGNAVTA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            complement(14358..15401)
                     /gene="mreB"
                     /locus_tag="LSX49_001692"
     CDS             complement(14358..15401)
                     /gene="mreB"
                     /locus_tag="LSX49_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HBL7168117.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            complement(15706..17646)
                     /gene="csrD"
                     /locus_tag="LSX49_001693"
     CDS             complement(15706..17646)
                     /gene="csrD"
                     /locus_tag="LSX49_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HBL7168118.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLLSNDFSTLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGTND
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIILMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLCEIQNAREQHSRLDT
                     LIRSYAAQDMKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     LVEEQFFSLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIASQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGRVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLLISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRRRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            17798..18772
                     /locus_tag="LSX49_001694"
     CDS             17798..18772
                     /locus_tag="LSX49_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL7168119.1"
                     /translation="MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRILPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPARRA
                     QAWQRLVTDLPESFYTQAAKEISLAEAPKFAEAIINNQIQGRTLVKVN"
     gene            18809..18973
                     /locus_tag="LSX49_001695"
     CDS             18809..18973
                     /locus_tag="LSX49_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168120.1"
                     /translation="MKSLFNQLTGKAVSRTAFVEHLGYEVVQHHPNWKVMISTDHKLM
                     RIDAPPNSHY"
     gene            19749..20219
                     /gene="accB"
                     /locus_tag="LSX49_001696"
                     /gene_synonym="fabE"
     CDS             19749..20219
                     /gene="accB"
                     /locus_tag="LSX49_001696"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBL7168121.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            20230..21579
                     /gene="accC"
                     /locus_tag="LSX49_001697"
     CDS             20230..21579
                     /gene="accC"
                     /locus_tag="LSX49_001697"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBL7168122.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA
                     SGGGGGRGMRVVRSDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            complement(21671..22717)
                     /locus_tag="LSX49_001698"
     CDS             complement(21671..22717)
                     /locus_tag="LSX49_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL7168123.1"
                     /translation="MKNEIWSWIGDLSQVAGIKHYELRSGRAKGTEAFDVRTGAGLAF
                     TVVKDRALDIAWASYKDTALSFITPNGVVAPAFFESQGNGFLRSFYAGLLTTCGLSYI
                     GTPCEDEGETLGLHGRLAATPAEEVGYRTERTDDSIEFVINGKVRETRLFGENLTLER
                     TIRCRYGENVMRIEDKVTNHGFTRQPLQILYHFNYGWPLLSPQAEILLSAKSITPRTP
                     HAAEGLTSHLEICTPQPGFDEQVYYLTLNSDSQGMSKVALVNAELGWGIYEKFDTMQL
                     PNFIQWKNLGAGEYVMGLEVSNSFPDGRDKERAQGRLPFIEPGETKKYCFELGIVDGD
                     AEISALKAEIAGYR"
     gene            complement(22714..23676)
                     /locus_tag="LSX49_001699"
     CDS             complement(22714..23676)
                     /locus_tag="LSX49_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL7168124.1"
                     /translation="MSKVFTIGEILVEIMASKIGQPFDQPGIWNGPYPSGAPAIFIDQ
                     VTRLGVPCGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDR
                     DFIFNIKNAACGKLSAQHVDENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIVKANGG
                     VISFDPNIRKEMLDIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPERAIAGFLEE
                     GVKEVIVKRGNQGASYYSANEQFHVESYPVEEVDPTGAGDCFGGAWIACRQLGFDAHR
                     ALQYANACGALAVTRRGPMEGTSRLMEIETFIQRHDMSIREAAQ"
     gene            complement(23698..24687)
                     /locus_tag="LSX49_001700"
     CDS             complement(23698..24687)
                     /locus_tag="LSX49_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7168125.1"
                     /translation="MTEKTLASPKPSGIPIANNFKKVFRQYGGILSGMVVLIILFSFI
                     NDSFFTANNITNIILQVSIIAITAYGMTYVLLLGDIDLSVGSTIALIGTFAALGASWG
                     IPFVLLVPLSIIAALALGMINGGLTAIAGIPSFIVTVATMGIFRGIAYIVTDGMPIMI
                     KDDAFLALGNGEFLYIPIPIWILIILLLINHFILTKTTFGRKIYITGGNKEAAIYSGI
                     NVTRLKIKVFMITAVLAGISGMILASRLYSGQPNSALSYELDAIAAAVLGGTSLNGGY
                     GTVVGTVIGALTIGVINNGMNLMNVPYFYQMVVKGLVILVAVYFDVRNKRKRS"
     gene            complement(24688..26187)
                     /locus_tag="LSX49_001701"
     CDS             complement(24688..26187)
                     /locus_tag="LSX49_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL7168126.1"
                     /translation="MTDVILDVSHIAKTFGHVQALKDITLSLRKGRVHTLLGENGAGK
                     STLMKILAGVYPPTQGTITLRGETITINNPQHSRQLGIAIIFQELSLSNNMTVAENIY
                     ANNEPRRFGIINDKKMLADCQNLLAELGIPLDPLEMVGNMSMAHRQLVEIAKALSYAA
                     DVVIMDEPTSSLSDNEAEILFNIIEKLKQRGCAVIYISHRMDEIMRISDDISVIRDGE
                     YIATHEKKNSDIQHLIAQMVGREMKNIWPARLGEKPDENVPAKLEVKNLSHPSLFKEV
                     SFAVRPGEVLGFFGLVGAGRSDVMKALFGLVSYHGTVLIDGKEVRIANPKQAIDHGIA
                     FVTENRKEEGLVLMHDVNMNTHHVAFQYNASRMGLINHRQEEAKTLQSIARMNTKVSS
                     VHQAVGALSGGNQQKIVLSKWLEKTPRILLLDEPTRGVDVGAKFEIYNVIRQLAAAGT
                     AIILVSSELPEVMALSDRLVVMRNKTIADIYSCENLTQTQVMTAATGVR"
     gene            complement(26248..27138)
                     /locus_tag="LSX49_001702"
     CDS             complement(26248..27138)
                     /locus_tag="LSX49_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL7168127.1"
                     /translation="MKNIKLLGSAMLVSLALFSQSSLAKEYKIGASLLTQQHPFYIDL
                     ANAMKEEAKKDNVNLSVSIANQDLNKQLSDVEDFITKKVDAIIISPVDSKGVQAAIIK
                     ADKAGIPVITVDVAAEGVPVVSHVATDNYAGGVEAGKLMGKLLSGKGTVAIISYPALQ
                     SVVARVDGFKKGLSDTPDIKIVAEQPGITRAEALTTAQNIMQANANLNGLFGFGDDAA
                     LAAVIAAKSAHNDNIKIIGFDGMKEARDAVDSEKTFAAVIRQYPDQMGAKAIDAAVDH
                     LNGKPVEKMIPVQPGVYTGK"
     gene            complement(27174..28028)
                     /locus_tag="LSX49_001703"
     CDS             complement(27174..28028)
                     /locus_tag="LSX49_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose bisphosphate family class II aldolase"
                     /protein_id="HBL7168128.1"
                     /translation="MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSP
                     VMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLDHHEESDDIFNKVRAGIRSVM
                     IDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLRVDEKDSAYTSPAAA
                     TEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDV
                     QHCIRRGICKVNVATELKIAFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIG
                     VCGSEGKI"
     gene            28369..29199
                     /locus_tag="LSX49_001704"
     CDS             28369..29199
                     /locus_tag="LSX49_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7168129.1"
                     /translation="MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGV
                     TIRGDLSYLEQQGYLKRSFGGAIATPLSSEPEAIQPIAPLSLAQQMEIARHCARLIRD
                     RDTLFLGHGTICRKIIPLLSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDT
                     ALAGKQLEQALQHFTITHSILEISHLDADGTLNINVPRLAAAWQLCFDHAQNKTVIVA
                     ADPAPSTAAIGHLHQAENVIVSRSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE
                     "
     gene            29231..30166
                     /locus_tag="LSX49_001705"
     CDS             29231..30166
                     /locus_tag="LSX49_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL7168130.1"
                     /translation="MGELLAEFLSRNPHQKFTQPGEFIGPFPSGAPAIFAAQVAKLSH
                     RAIFFGCVGNDDFARLIIERLRHEGVITDGIHVMNNAVTGTAFVSYQNPQLRDFVFNI
                     PNSACGLFTAEHIDKDLLKQCNHLHIVGSSLFSFRMIDVMRKAITTIKSAGGTVSFDP
                     NIRKEMLSIPEMAQALDYLIEYTDIFIPSESELPFFARHKNLSEEQIVSDLLHGGVKH
                     VAIKRAQRGASYYKLKNGTLHAQHVAGHDIEIIDPTGAGDCFGATFITLFLSGFPAHK
                     ALQYANASGALAVMRQGPMEGISSLADIEDFLQQH"
     gene            30259..30501
                     /locus_tag="LSX49_001706"
     CDS             30259..30501
                     /locus_tag="LSX49_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HBL7168131.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLPGVAPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVRFIYRDIPLEDDDAA"
     gene            30491..31942
                     /gene="panF"
                     /locus_tag="LSX49_001707"
     CDS             30491..31942
                     /gene="panF"
                     /locus_tag="LSX49_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HBL7168132.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVDTLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLAKLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            31954..32835
                     /gene="prmA"
                     /locus_tag="LSX49_001708"
     CDS             31954..32835
                     /gene="prmA"
                     /locus_tag="LSX49_001708"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBL7168133.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            33164..34129
                     /gene="dusB"
                     /locus_tag="LSX49_001709"
     CDS             33164..34129
                     /gene="dusB"
                     /locus_tag="LSX49_001709"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBL7168134.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            34155..34451
                     /gene="fis"
                     /locus_tag="LSX49_001710"
     CDS             34155..34451
                     /gene="fis"
                     /locus_tag="LSX49_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HBL7168135.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            34536..35420
                     /gene="yhdJ"
                     /locus_tag="LSX49_001711"
     CDS             34536..35420
                     /gene="yhdJ"
                     /locus_tag="LSX49_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HBL7168136.1"
                     /translation="MRTGCEPTRFGNEAKTIIQGDALTELKKLPAESVDLIFADPPYN
                     IGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLF
                     TIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
                     NYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIV
                     LDPFAGSFTTGAVAVASGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTG
                     NLSKRSRLSEVDPDLIAK"
     gene            35504..35683
                     /locus_tag="LSX49_001712"
     CDS             35504..35683
                     /locus_tag="LSX49_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HBL7168137.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNP
                     LKLVNCDELNFQDRM"
     gene            complement(35686..36348)
                     /gene="acrS"
                     /locus_tag="LSX49_001713"
     CDS             complement(35686..36348)
                     /gene="acrS"
                     /locus_tag="LSX49_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HBL7168138.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQDHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
                     VVMIIIDGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHKTNELS
                     VI"
     gene            36747..37904
                     /gene="acrE"
                     /locus_tag="LSX49_001714"
     CDS             36747..37904
                     /gene="acrE"
                     /locus_tag="LSX49_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HBL7168139.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQA
                     SYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
                     ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQS
                     SNDFMRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLR
                     AVFPNPQHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNNKSQVEAR
                     PVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
     gene            37916..41020
                     /gene="acrF"
                     /locus_tag="LSX49_001715"
     CDS             37916..41020
                     /gene="acrF"
                     /locus_tag="LSX49_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HBL7168140.1"
                     /translation="MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVS
                     VSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDI
                     AQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVAS
                     NVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ
                     LGGTPALPGQQLNASIIAQTRLKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN
                     VIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ
                     LSIQEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPREATEKSMSQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK
                     GGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEE
                     DQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAG
                     MAFVSLKPWEERSGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFE
                     LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGV
                     SLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMV
                     PFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGY
                     DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA
                     ATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLR
                     PILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR
                     CFKG"
     gene            41273..41494
                     /locus_tag="LSX49_001716"
     CDS             41273..41494
                     /locus_tag="LSX49_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168141.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            41925..42950
                     /locus_tag="LSX49_001717"
     CDS             41925..42950
                     /locus_tag="LSX49_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7168142.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDVCRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPTEWIVL
                     PEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            43018..44199
                     /locus_tag="LSX49_001718"
     CDS             43018..44199
                     /locus_tag="LSX49_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL7168143.1"
                     /translation="MPHRRSTVKGSLSFANPTVRAWLFQILAVVAAVSIVGWLFHNTV
                     TNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRIFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWP
                     FAAVLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSIYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            44209..45312
                     /locus_tag="LSX49_001719"
     CDS             44209..45312
                     /locus_tag="LSX49_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL7168144.1"
                     /translation="MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLVVWWLMYGGFLGLDRVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH"
     gene            45320..46078
                     /locus_tag="LSX49_001720"
     CDS             45320..46078
                     /locus_tag="LSX49_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL7168145.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEALAMHYLERVRIAEHAQKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFAHPKSERTRAFLSQVIH"
     gene            complement(46141..46256)
                     /gene="rrf"
                     /locus_tag="LSX49_001721"
     rRNA            complement(46141..46256)
                     /gene="rrf"
                     /locus_tag="LSX49_001721"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(46296..46371)
                     /locus_tag="LSX49_001722"
     tRNA            complement(46296..46371)
                     /locus_tag="LSX49_001722"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46336..46338),aa:Thr,seq:ggt)
BASE COUNT        11514 a        11897 c        11296 g        11669 t
ORIGIN      
        1 attcacattt ttaacactta gtatcaactg aaacagttag cgtggtatta attagttcaa
       61 taattagtgt atacttgatt ttgtgatatg ggtcacgaaa caaaggccca gctaaaagat
      121 tatgtcgagg taaaaatcat gaaaatcaaa accactgttg ctgcattaag cgtactttct
      181 gttctctctt tcggtgcatt cgctgccgac tccattgatg ctgcacaagc acaaaatcgt
      241 gaagcaatcg ggaccgtatc cgtaagtggt gtggcgtctt cgccaatgga tatgcgtgaa
      301 atgctgaaca aaaaagcgga agagaaaggc gcaacggcct accagattac tgaagctcgt
      361 agtggtgaca cctggcacgc tacggctgaa ctgtacaaat aaaccctcat cgtcttgtcc
      421 gacgatattg cccccggttc gggggctttt tttgcgctaa tgacgaacat taaaacgcaa
      481 atgcccttcc agctcttcct ctgcctcatc aaacagcaat attaacgcgc caaaacggcg
      541 acgcgttttc tctcccagat gaacaaattc aatctcaagt ggtagcggca ggacatcgtt
      601 cattaacaca tcccatagtg agtcgagatc gcgtacctta tctttcgcca gaccaaaggt
      661 ttggctaaag tcacgataaa aatcctcctg actctcaatc tcatcaaaat caaaggtata
      721 aatattcatc tgttgccacc gtcacgtttc gcggcgagtt ctgccgttca tcgctaagta
      781 tagccatgaa aaaaccgacg cttcaggcgt cggttttgac ttaactatcg gtcaacgcat
      841 gttgatactt atggagcata cccgtaagcc gatgtactgg ttccgtcacc tgcggtggcg
      901 cttgccagat gcgtagcttt tcctggtaga tttccagttc ttccagcaac tggccaaagt
      961 accgacgacg tttatcatcg ctacgggcag atatcacatg gtctgctgtg cggcgcattt
     1021 gtcggtgaaa cgccgataaa tcctcgttaa ccgggatcgg cgcatcacgc aggcgctggt
     1081 gcgcgataat catcgtcagc gccaggcgaa atttcggcaa atcccctggg aacttattca
     1141 tcagcaaaaa cagctgctga taaagtgccg ggaggtgatt ctctttacga cgtgccacat
     1201 tggtagtcat cgcggaaaca gcggcagaaa caaactgatt aagcagtaca cgtccagtcc
     1261 tgtcgcgcga tttatcccgc accagcaaaa taacggtgaa cgcgagcaca cagccgacga
     1321 tttgccctaa tgcgctgtcg agaaactgac tgaaatggaa agtcatcggg ttatccagca
     1381 cgataatgtt tatggtgctg gccaacgccc ccatcgagcc caatctccgt ttctgtactt
     1441 ctatgccgag gaaaaatccc agcactgcca ggctaataca cagcagcaac atgctctgtt
     1501 gggtattagg gataatcacc aaaaagtaga gcagccctaa cggcagcgct gccagcgtcc
     1561 cgtagataaa gtcgatcgcc accatgcatg gattcggcaa acgcattgcc agtgacgtca
     1621 cgaccgcaat catcaccatt gcaccactgc cggaagtcca gcccgtccac agccagaaaa
     1681 gcgtgcccag aatgcaagaa agtgtggttc gccagaagtt aaccattgca tgatgacgtt
     1741 cggctgactc tacttttact tccggttcgc cttgcaggat ctcttcttcg gtggcgttga
     1801 tttttgtgtt actgataacg ccgcgcttga gaagctgata acgcgttgcc gccgcgaccc
     1861 aactataaat ggtaacaggc gtttcccgtt ccccggtcca ggcgatcact ctccgcaggc
     1921 gtttgagctg cttgtggacg tcctgcgcag tttctaccgg cgtgtcaaaa aattcgcgga
     1981 aagtatcagt gatcaattcc gggcgcgtat tctgaataag ataagtttcg caggattggg
     2041 taatcagcgt cagcgatagc gtattgatcg cttttaaacg tcgattagcc cgcgcccagc
     2101 gggaagattc catattcagg ttgctgcgca taccttgtaa cgccgtagta cgtcgcacca
     2161 gatcgcccca ggctttatcg acaacttcac catcgccatg cttgatacag agttgcatta
     2221 attgatattg cgcgaccagc aaactttcca gctctcgatc cacttcttgt ttgatcgatc
     2281 gcggagaaaa gagcaaatcc gccataattg cacacacaat accgataacg atctcgctac
     2341 aacgttcgac ggcaaactgc ggcgtaagca atggttccgg ctgaatggtg atcacaatga
     2401 tcagcgcggt ataaccggcc agcccccacg catacgagtt ttctattcgt accagcgagg
     2461 atatccaggt acaaaaaccg gcccagatac agcacaccag aatcatcaat aatggtgctc
     2521 ggatcatcgc aatgatgatt accagtccgg caatacagcc aataaatgtg ccgatgatgc
     2581 gcaaaaagcc acgatagcga atagcgccag aatacggttc acctcccgca gcaaaggccg
     2641 gaccggcggc aacaatcgcc gctgtcagta ccgcccagcg tggcgtttcc agctggaagt
     2701 gaaagccaac aaacagcgcc agtacaatgg cggtcgccag ttttaccgca aagcgaatat
     2761 gttgattagc aatggagaaa atacccatcg tgattaacca aactcacgca ggcgatgagc
     2821 cattttacgg aagaacgaat cctgactttc gtcgcgatct tgtttgccag tgactaccac
     2881 cgtagcagtg gtgcccgcag gccagatgtt ctcttgctgg ttgtcgagac gaatacgtac
     2941 cggaacacgt tgcgccaaac gtacccattc aaggttagag tcgatggtcg ccatcccttt
     3001 gtcgtcacgc gtgctgctgg cattggtgac ccctgcggca acactatcaa cagtcccttt
     3061 cagcactttg ttactgccaa gcggcgtgat ctccgcacga tacccagggc gcaccccttc
     3121 cagcttagtt tcttccatat aggccagtac atagaaggag ttctgtttca ccagcgcaac
     3181 cgccgttgat ccacgggtaa taaactcacc ggtatagacg ttgaggttgg tcacccagcc
     3241 atctgctggc gcgcggatca ccgtgcgttc aagatccagt tttgccagat cgcgggtcgc
     3301 ctgcgctttc gctaactgat gcagaaccgt ttgtagtacg ttgttggcct ggtcgatctc
     3361 ttcgcgggac atcgcctgca caccgagacg gttacgacgt ccggcctcct ggcgtttctc
     3421 ctgtgccagt acctgataat aagcaacatc ggcttgcgct tcctcaagcg ccttttgata
     3481 gcgcggctgg tcgatggtga acagtacctg tccttttttc accagctggt tatcatgaac
     3541 attcacctgg gtaatgagtc cagaaacgtc cggcgcgatc gcaacgacgt cagcgctaaa
     3601 gcgcgcgtca cgcgtccacg gggattcggt gtaatagacc caggcattaa aaattgcgat
     3661 gaaggccaga atgactaata cgaccgtgat ggccgtacgg gagaattttc ttattagtgt
     3721 tttcacttca acctcaaacg aacagtcgcg atatcaaata aaacaagcag caatagagcg
     3781 cggtgttgaa caacgccgga tgccagacaa agtcgtagat acctgttggc acaagtaccc
     3841 ggcgcaccag ccagaaaatc gccagtgata aaagcaattc gaaaaatatc ggtgggaagg
     3901 acagcccaaa caccacgata acgggaaaca gactcatgtt gaccttggtt gtatagagag
     3961 agcaggcgtt attattttca gcatctgtcg ccgcagagaa gggcatagaa agccgggcga
     4021 gagcaacatt gctgtagatt gatatttaat atattaacgt aactgttatg ctgttatcta
     4081 tattatgtga tctaaatcac ttttaagtca gagtgaataa tggaacgact aaaacgcatg
     4141 tcggtgtttg ccaaagtagt tgaatttggc tcttttaccg ccgccgccag acagctacag
     4201 atgagcgttt cgtccatcag tcagacggtg tcaaaactgg aagatgagtt gcaggtaaag
     4261 ctgttaaacc gtagcacacg cagcattggc ctgaccgaag ccggtagaat ttactaccag
     4321 ggctgccgtc ggatgctcca tgaagtgcag gatgttcatg agcaactgta tgccttcaat
     4381 aacaccccca tcgggacgct gcgcattggc tgttcttcaa ctatggcaca aaatgttctc
     4441 gccgggctga cagcaaaaat gctgaaagaa tacccaggtt tgagcgtcaa tctggttacc
     4501 ggaattcctg cccccgacct gattgccgac ggtctggatg tggtgatccg cgtcggcgcg
     4561 ttgcaagatt ccagcctgtt ttcccgccgt ctgggcgcga tgccaatggt ggtgtgcgcc
     4621 gcaaaaagct atctcacaca atacggcata ccggaaaaac ccgccgattt aagtagtcac
     4681 tcatggcttg aatacagcgt gcggcccgac aatgaatttg aactgatcgc accggaaggg
     4741 atctcgactc gcctgatccc acaaggaaga tttgtgacta atgatccgat gacgctggtg
     4801 cgctggctga cggcgggtgc cgggatcgcc tacgtgccgc tgatgtgggt gatcaacgag
     4861 atcaatcgtg gggagctgga gatcctgctg ccacgttacc agtcagatcc acgcccggtt
     4921 tatgcgttat ataccgaaaa agataagctg ccgctgaagg tacaggtcgt gatcaactcg
     4981 ctgacggatt attttgttga ggtcggtaaa ttgtttcagg agatgcacgg gcgcgggaaa
     5041 gagaagtaat taatattgta ctgttacgtt gtacaaacct gtgccgacgg gttcccctaa
     5101 ccccagaggg gcgaggggac cgttcgtgca cggagaagga ttaattatcc ttctgaaaat
     5161 actgaaatta ttacgcagta ccgccaacag tcaggttatt aactttcagc gttggctggc
     5221 ccacgccaac cggcaaactt tgcccttctt taccgcagac acccacgccg ttatccagtt
     5281 tcaggtcgtt gccaaccatc gaaatctgct gcatggtttc gataccggaa ccaatcaacg
     5341 ttgcgccttt caccggctta gttactttac cgttttcaat cagatacgct tctgaggtgg
     5401 agaaaacgaa tttgccggag gtgatatcca cctgaccgcc accaaagttc ggtgcataga
     5461 taccgtactc aacggattca ataatttcct gcggggtcga tttacccggc agcatatagg
     5521 tgttggtcat acgcggcatg ggcagatggg cgtaggattc acggcgaccg ttgccagtcg
     5581 gcgtcatccc catcaaacgc gcgttgagtt tatcctgcat gtagcctttc agaatgccgt
     5641 tctcaatcag cacgttgtac tggcctggcg taccttcgtc atcaatcgcc accgaaccac
     5701 ggcgatcgac catcgtgcca tcatcaacca cggtacacag ttctgaagcc accaactccc
     5761 cgacctgtcc actaaatact gaagtgccac ggcggttgaa gtcgccttcc agaccgtgac
     5821 ccaccgcttc atgcaacagc acgcccggcc aacctgcgcc aagtactacc ggcatggtgc
     5881 ccgctggtgc agcaacggca gaaagattga ccagcgccat acgcactgct tcttttgccc
     5941 acgcatccgc acggacttcg ccgtcgagat cggcaaggaa gaactcataa ccaaaacgac
     6001 cgccgccacc actggcaccg cgttcgcgtt tgccatcttc ttcgaccaaa acgctcacgg
     6061 aaagacgcac cagcggacgg acatccgccg ctagtgtgcc gtcggtggcc gcaaccagaa
     6121 ttaattcata gacaccactg aggctggcag tcacttcctg tacgcgcttg tccgcttcgc
     6181 gggcaacctt atcgacgcga cgcaggatat ccaacttctc ttcacggctc atgctttgca
     6241 gcggatctac cgaggtatat aacgggctat gctctaccgc gcccagcgtc tgtactttgc
     6301 catcaccact atcacggacg atggtgcgcg ccgcttgtgc actctgttcc agcgccagca
     6361 ggctgatttg gtcagcataa gcaaatccgg ttttttcacc actgattgca cgcacaccaa
     6421 cgccctgatc gatgttgtaa gaaccatctt taataatacg gtcttctaaa acccaggatt
     6481 cgtgatagct cgactgaaaa tagagatcgc cataatcaag gcgacgttcg gccagttgac
     6541 cgaggatcgc gaacaagtcc tgatgtttca ggccgttcgc cgctagcaat tgttcactta
     6601 ccaggttcag actcatcgtt tttgctactc gttagttact gcagtagagg attttttacg
     6661 gctgccggat gcggcgtgaa cgccctgtcc ggcctacggt tatgttctgg ctcgttggcc
     6721 tttggcaacg attatcatat gagattgggg caattacgcg ccctcgtcaa atcattgcgc
     6781 tttttcttta cgcggttgtc gcaacacttc gttgatttgc ggatcgtcca gcggacccga
     6841 aatgtgatag cgcaaaatgg agactttgct ccacagcggt cccagcactt tactggcggc
     6901 aaacactgcc gcgccaacaa tggggttaac cgcaaaggcc gcagccacac ccaccgtcgc
     6961 agaaatctct ggtgcgacaa ccgcttccat attcaggtcg cgacgtacca gatttaccga
     7021 ccctttcatg gcgatgtccg cttccaggcc atccaccagc gtgtcgtcgg tgtgcataac
     7081 gccgtcttta atccacgcgg tgctgcgaat ggagtcaaaa tagaaccctt cgccaaaagt
     7141 gtctctgaaa tcaaaacgca gcttacgcat cagggcatct acgctcaata agcgcagcaa
     7201 ttgcccggca tgtccggtat tgatttcggt aatttcgcct ttacccagtt gagtatgaat
     7261 gatgccattc aacgtcgcct catctggctg ccagggtgct ttgcgccagt gtaaatcgta
     7321 atccacatta aatgacgact ggcgtatggg cgtcgtgaca ccaaaaaatt ctgcggcggc
     7381 atcaattttc tgcccgcgca gttttccttt cagcgaggtt cgttcattcc ccggattgtt
     7441 aacccattca ccatcggcag tgagccgcgc aaaaccagta tcaatcagtc cattagtcag
     7501 cgttaacgta tcgccagaaa tggtgatatc actgtcaatg cgaccgaatt tttgccccca
     7561 gaaccagcac tctgcgcatc gtatttgtgc gtctggccag ccacggaagc taatgcgttc
     7621 cgttgtcggg aaaggtgatg actgtgttga atcaccacga gttttcgcca cgcttgggtt
     7681 gtaataaaga tatttgatat tcgccagcca cggcgcgtta ttacgcatcg ccagcgtggc
     7741 gttgatttca cgcccttgcg cctcaaccag ggtgccattt gccgtcggtt gcgaaacaat
     7801 actcaggtta ttccattgct gatttcccag cgacaacata ggcgtacgta acgttatgtg
     7861 ttgtgggaaa ctcgctgcac caccgacact ctccgccgcg cctttctgga acagggccag
     7921 ccactcggca ccattcatcg gcggcatatt gagttcaacg ccactttgtt ccggcaacgg
     7981 cgggagcgtt ttactgtctg ccgcccaaat agcacgatcg agcgtcagct tttgaccgag
     8041 caaccagcgg ctattgaaat agttatccgc accagcctgt ccggttaatt caaagctgtt
     8101 gagattgcca tcaaccttaa cgtttaccga tagtggttca cccgcaggtt tggctaacgg
     8161 tgaaggtaag tgactgctca cattcttcaa atcgccgttc agctctacgt tatacgtcgc
     8221 gccagcatga taaggcagct caatgcccac tttaccatcc cacgccacgc tgccacttaa
     8281 tgcttcgttc accgctgcag gcagaacgcc ggttttcgct ggttgccagt taccgttgag
     8341 attcaccgcg acctggtagg cttttgcccc ttctttggtg gaaaaatcca cgttcaacgg
     8401 ctgattaaac cagcttgctg tcagtggttc actttgcaga tcgccattga taaagctgaa
     8461 tttaccgctc aaatttttca gggtgctgtc gagtggtttg ataaacagac tgttattacg
     8521 cagcgtcact tcacctttcg cggttaccaa ctcgccgttc agcgggatat caagatgtaa
     8581 gcgagcattc acatcgccgt cgagctggag ttcttgcagg gtcgcaccca gggaatcttt
     8641 cagcggtgtc tcatcaaagt aagggccaac ggctttaccc ggacctttaa tgtcagcgtc
     8701 aatcagcagt ttttcttttg agtagtcagg gatcactgcg gtgagattac tcgcgcgcac
     8761 gccgcccaga ttaacgccat cggttttcat ccataaaccg tcgttaataa agtccagttc
     8821 aatatcaagg ttagttaatg caggccagtc cggctggaag gcaaacttcg cgttgcgcag
     8881 cggcaccagc acttcaaact gaccttcgtt gtgtttatag gggaagagtt gcggattgcc
     8941 accataaacc agcgtcgcgt tatccgcttc accgccctga atcgcgccac ttaagtaatc
     9001 aaccaggtct ttacccatca agttttccgg gaaatagcgc caggcttgtg aaccatcatc
     9061 ggtactgatg ccagccagaa tacccagcca gggttcatcg ttagcaggtt gcaggtaacg
     9121 aaaaccgccg cgcgcatgga cggctttggc tttaacgtca atattacgcc catccagctg
     9181 gaaacctttg tcattgttca gccagcttat cgttgcctgg ccgtcggcga tttccagtgg
     9241 cgcacggaat accgtttcgt aaggcatctt tgcctgcttc atcgacgcag taagcaaacc
     9301 attttctacg ctgccggaaa gcgtcccgga gaagtgttcc gcacccggta ataatttcca
     9361 ttgcttccag gccagatcgc tccacgatgc ctgaaaacgg gtcttgtctg ccgcctgaag
     9421 cgggatatcc agcgccagag tgttaatctt gccgctcggt tgtgtggagc gccaaacatc
     9481 acccagtgca ggtgaaagtt tcgcgaccag cgggcgtacg ccctccagcc ctgccagctc
     9541 cagattactg gcacgaatcc ggagttcgtc actgcgttta ttgtctttgc cgccaacgtc
     9601 ctgttccggt atccaggcca gcgtcaatgc tccgctcggc cagggtttgc cgtccatcgt
     9661 gatccgtgta tcgggaatag agaactgcca tcccggattt tcacgcgtaa tatgcgcagt
     9721 cagattatcc accgacagcg tatgcgtttc cttctcgccc aaccagctgg caccgccctg
     9781 tttcagccag acgtcaccgc cggttacatc gcctttgtcg atcgtcatcc agccttcaag
     9841 ggagaactgt gccgtttcca gcgcaatatt gtcctgcatc catttaccga gccacggctt
     9901 caggtcgatg tcatccgcct ggagccagac gcgaccattg cttaacaacc cctcatcatc
     9961 gcgcaaatcc atacgcacct gcatcacgcc gtgctgtccg gtaaggctgg agaggcttac
    10021 caggccttcc gcacggtgtc gacgtggatc gttcagccag gtgagctgtg ggatcgccag
    10081 ctcggcgcgc tgaccggatg gcgtcaggaa actgacttca ctgtcgcgga gatcgaaatg
    10141 gtcaaattga cgaagaaaca gatcgctgat gtgactggct tccaggctat cattaccacc
    10201 gccgctggtg atagaagtgt tggtgcgaaa gcgcagctgc cagaaagtga ggtcgcgaaa
    10261 ctgccagcgc atatgtaaca ggctctgcca gacatccagc gccagggtaa cgcgtttaac
    10321 cgaaaattcg ccgccatctt ttagttctgc acggatgtcg tgcgcttcaa gcgtcggacc
    10381 aaaattctgc cagctggctg agagctgact ggcttctacc ggcatgccag tcgcggattc
    10441 tattttgttg aggatttccg gacgccaggc gtcaagatgc ggtaaagcaa tacgcaggcc
    10501 gctaaccagc agggcagcga tcacaacgag cgcggctcca gtaagcagta aaatccccgg
    10561 caatcgcctc acccgtcact ccttgtctgc taaaaatgtg actcaaaaac cctttgccgg
    10621 atggcggccc agcatctgtt tacatcatta cgacgtcaaa ctgctcctgg ttatagagcg
    10681 gttcaatttg tactttaacc tgtttgccaa cgaaaatttc cacttccgcc agcgagtgtg
    10741 actcttcgcc tttcaaggct tcggctactg ccggagaagc atagaccagg aaacggtcgg
    10801 agtcgtaagc atggtggaca cgaacaatct cgcgcatgat ttcatagcat accgtttcca
    10861 cggttttcac cgttccgcga ccgtggcagg ttgggcattc gttacacagt acgtgctcaa
    10921 tgctttcgcg ggtgcgttta cgcgtcatct ccaccagccc cagcgccgaa aaaccattaa
    10981 cgctggtttt cacccgatct ttgctcaacg cctgctccag cgagtgcagc acgcggcgac
    11041 ggtgatcttc attattcata tcgatgaaat caataatgat aatcccgccc agattgcgca
    11101 accgtaactg gcgagcgata gcctgcgtcg cttcaatatt ggtattgaaa atggtgtcgt
    11161 ccagattgcg atgaccgaca aacgccccgg tattgatgtc cacggtggtc atcgcttcgg
    11221 tctggtcgat aatcagataa ccaccggatt tcagttctac tttgcgttcc agcgctcgct
    11281 ggatttcgtt ttcgacatca aagagatcga aaatcggctg gcgtccggtg taatgctcca
    11341 gcttgctggt catctcggga atgtactctg aggtaaactc cagcaatgct tcgtaagtca
    11401 ggcgtgagtc aacgcgaatg cggtcgagtt cggcgtcggc gaaatcacgc agaacacgct
    11461 gcgccagcgc cagttcgccg tacagctgat aacgggtctg cgggcgtttt ttacgctcca
    11521 taactttggt ccagacgcgt ttcagataag cagcatcgga ggccagttcg gcctcgccaa
    11581 ccccttccgc tgcagtacgg atgataaacc cgccctgctc gtcgcaatac tctgcgacca
    11641 cttttttcag gcgttcacgt tctgattcgc tttcaattcg ttgggatacc ccaacgtgag
    11701 aagcccctgg cataaacacc agatagcgag aaggcagcgt gatatcggtg gtcaggcgcg
    11761 cacccttagt gccaagcgga tctttcacca cctgcaccat cagatcttgc ccctgacgga
    11821 ccagttccga gatgtcgcgc accgtgaatt gcttttgttc ttcacccgcc acacattcgg
    11881 tgtgcggcat gatgtcagat gcatgaagaa acgcggcttt atccagccca atatctacaa
    11941 aagccgcctg catacccgga agtacacgac ttacacgacc cttgtagata ttgcctacta
    12001 ttccgcgtcg cgcctcacgt tcaatatgaa tttcctgcag aataccgcca tcaatatacg
    12061 ccactcgagt ttccgaaggc gttacgttta ccaacaattc agccgtcatg tttatccctt
    12121 ttctcacgca gtgcgttaaa attacttaat aattcatacg tttcaaccag cggtaagccg
    12181 actacggcgt gaaagctgcc atttatcttc ctgacaaaac agccacccag cccctgaata
    12241 ccgtatgcac ctgctttatc taacggttcg ccgctggcga catagcccgc gatgtcttcg
    12301 tctgttaacg ttctgaaagt cacatcggtg accaccaggc aatcgagaat gtgctggctg
    12361 tcggccaacg ccactgccgt catcacctga tgggtctgac ccgataattt gcgcaacatc
    12421 tgcgccgcat gctctgcgtc gcgcggtttc tcgagcactt ctccattcag gataacgata
    12481 gtatccgcac ccagcaccgg gagatcctgc gccgtttgcg cgacacccgc ctgtgctttc
    12541 tcgcgcgcca gacgcacaac atactgctgc gcgctctcct gcggctgacg ctgctcctca
    12601 atgcccgtaa caatacgttc aaaggtcacg ccaagttgcg caagtaactc ctgacgacgc
    12661 ggagaaccgg aagctaaata cagagaagtc atagaaacct ttattgcact gcaaactgct
    12721 gacggacttt acgcatcagc aagaaaatcc acggccagag aacgccattg actacactac
    12781 tccagaacac ttccggtctg aaagagacgt taatcactaa aaactctgcc cagaaaacaa
    12841 taatatccac caccagcgaa agcaacatga cgaccagcgc ctgctgccat aatgcgaggt
    12901 tgcggaaaag ctggtatttc agcgccacca ggtaagcaat gatgctcatc gccaatacgc
    12961 gtacgccaag cgtcgagccg ctgatcagat ccagtatggc acccatcaca aaacctgtgc
    13021 ccacatttac gcgatggggc aaggccagga tccaatacaa caagatgagt aacacccagt
    13081 ttggccggaa aacaatcagg ttgtccggcc atggcatgat ttgcagcaac agcgcaatga
    13141 ggaaagagag ccagattacc cagcgtccct ggctacgata gctcgccact attgtcctcc
    13201 cggcgcacgc gcaggcggtt gagcaccact ttgcggcggc gtagcccttt gtggagagcg
    13261 attagcagcg ggctgtgtgg gcgcagcagg cgcagtaact gcatttcctg tcgccggttg
    13321 ctgcggagtc ggctgagtga tccccgttgc cggttcaggt aactttggcc ccatcgcgtc
    13381 tggcgaaggc aatacctgcg gcatcatctg catcagacgt tcattagcaa cacgatgcac
    13441 ctcttccggc gtcatcgggt tagcgccgtt acgatccgcg ccccacagca gcagcagata
    13501 acgcaaacgt tgcagtcctg cagtcggacg cgcctgaatc acagtataag cgcgctgggt
    13561 atcgagtttt acggaagaga caaccgcgac cggatagcct tccgggaaac gaccgcccag
    13621 accggaagtc accagcacat caccaacacg aatatccgta ttcgctggca gatgctcaag
    13681 ctgcaaatca tccgtacaac cgttaccggc tgcaattacg cggatatcgt tgcgcagcac
    13741 ctggattggc agcgcgtggg tcgcatcaca aatcagcagc acgcggctgg tcagtttagc
    13801 gacggccacc acctgaccaa caacaccttt gtcgctgata accggctggc cttcataaac
    13861 gccattaacg ctacctttat cgataacaac ttgatcgcta taaggatcgt taaccgtgga
    13921 gataacctga gtcaccattt tctgctcatc ctgacgcagc ggggaaccca gcagctcgcg
    13981 cagacgcgcg ttctcctgtt tgtattgtcc aagcatcagc agttcactgt ttttcagcaa
    14041 cagttcctga cgtaacgccc ggttttcaag ttctagttgg tcacgcgagg ccagcgtctg
    14101 cgatacgcca tccagcaatt cacgaggagc attggaaaca aagtagaaag gactgacggc
    14161 ggtatccata taagtacgga tttgactgaa cgtccccagg cggctgtcgg caataataat
    14221 gccgagcgcc accagcaccg ccagaataag gcgaatctgt agcgacgggc cacggctaaa
    14281 aattggcttc ataagttatg cgtattctcg tatcagacca ggcagggtaa acagacactt
    14341 cccctgcctg catccgatta ctcttcgctg aacaggtcgc cgccgtgcat gtcgatcatt
    14401 tccagcgctt tgccgccacc gcgcgccaca caggtcagcg ggtcttcagc aacaacgact
    14461 ggaatgccgg tttcttccat taacaaacgg tcaaggttac gcagcagtgc gccaccaccg
    14521 gtgagcacca tgccgcgctc ggagatgtcg gaagccagtt ccggcgggca ctgttccagt
    14581 gcaaccatta ccgcgctcac aataccggtc agcggttcct gcagtgcttc gaggatttcg
    14641 ttggagttca gggtaaaacc gcgtggaaca ccttctgcaa ggttacggcc acgaacttcg
    14701 atttcacgga cttcatcgcc cgggtaagcc gaaccgattt cgtgcttgat acgttctgcg
    14761 gtggcttcac cgatcagaga accgtaatta cgacgtacat agttgatgat agcttcgtcg
    14821 aaacggtcac caccaatgcg cacggaagag gagtaaacca cgccgttcaa ggagataaca
    14881 gcaacttcag tagtaccacc gccgatatca accaccatag aaccggtcgc ttcagaaacc
    14941 ggcaggccag caccaattgc ggcagccatc ggttcttcaa tcaggaagac ttcacgggca
    15001 ccagcgccct gcgcggattc acgaattgcg cggcgttcaa cctgggtcgc gccaaccggc
    15061 acacaaacca gaacgcgcgg gcttggacgc ataaagctgt tgctgtgcac ttgtttgatg
    15121 aagtgctgga gcattttttc agtcacgaag aagtcggcga taacgccgtc tttcattggg
    15181 cgaatggcag caatattgcc cggcgtacgg cccagcatct gcttcgcgtc atgacctact
    15241 gcagctacgc ttttcggtga accggcacga tcctgacgaa tggccaccac ggaaggctca
    15301 ttcaatacga tgccttgtcc ttttacataa atgagggtat tcgcagtacc caggtcaatg
    15361 gacaagtcat tggaaaacat gccacgaaat tttttcaaca tactaaggga taatcctgaa
    15421 agctggggcg gaaaagaaaa tccgcttact ttaccaacca cacgcagcag cgacaaggcg
    15481 caaaaatcat ctgctacggt gaaaattagt gcagttcgtt tcctttgtta caaatctctg
    15541 cctgagtcca gaaaggctta atgcatcagc agcattcctc gcctgtttgc aaccgcgtaa
    15601 ggtcattcat ctgcatatgt gctgcaacaa tctggcgagc agacaagcac actcccatga
    15661 gacgcagcgc gcgttattct acgtgaaaac ggattaaacg gcaggttaaa ccgagtatct
    15721 ttgtgaatat tttttcacgt tagtatcaag tggctgtgag gacgcgaaaa aatccccttg
    15781 cccacctgta acaccgcgct gaatcagggt ctgccactcg cttcgcgaac gcacgccggt
    15841 ggcgtaaacc tgggtgctgg tcccggagca ggcttccacc aggctttgaa ccagcagctg
    15901 gttctccgtt cgcttctcaa tgtttctgac cagccccgga tggagcttga gtaactcaac
    15961 attaagttct ttgatccaac tggtgcttac cagcgtcaaa ccagcctggt tgacggctac
    16021 ccgtacccct aaagcattca ctaaacgaat aacaggttgt aagcgactga tatgttgacc
    16081 aacatcggcc tctgcaagtt caataattat gcgtcttcgt tgcgattttt cacattgcat
    16141 taacgtatcg cgcagccaac gctgaaaacg cgggcgaatc agcgactcaa cggtaacctg
    16201 aatcgccaga ttttcctctg gccagtaacg caatagtgga ataagacggc tgattagcaa
    16261 gcggtcatac tcttccgata aaccaaactg caagaccatc ggcatatact ctgccgagct
    16321 aacctcttca ttaccatcga agatgcggca catgagttca cgatgatgaa cccggccttc
    16381 gcgagtaacc gccggttttt gataaaggcg cgggccgccg cgactgagca tttgctcgat
    16441 aagcgtacgc cagcgaacat taccgcgtcc tttttcaggc aacgagtcat cgtaaatagc
    16501 ccagctattg ccgccctgca atcccgcatt acgcgtggca gactctgcat gttccattac
    16561 ctgctcggta tcctgaccac tacgccaggc acagatacca atgtggatca tatcgtcgcg
    16621 atcgagcatt ttattgttcg gcaaggtatc gacggctttg attaactgac tggcgatgct
    16681 ctctgcctct tttagcgtcc ggtgcggtaa cagcgcagca aaatcactgc gatggtaacg
    16741 cgccagcagt gcgccagggt agcgcatcat aaatgtcgat agcagattcg tcagagagaa
    16801 gaattgttct tcaaccaggc tgtgccccca ggtatcactc aacatattga aatccggcag
    16861 acgaatcatc atcacgatcc cgtgggtacc tactttctct tgatcttcca gtaacgttgc
    16921 taactgatta tcgaaaaaga gtcggttatt gaggccggtt ttcatgtcct gggcggcata
    16981 agagcggatc agcgtatcaa gacggctgtg ttgttcgcgt gcgttctgaa tttcacaaag
    17041 cagcgtatcc agcgcactgc tggttctggg cggccattca tagatggttc ccaacacatt
    17101 agagccacgc tcaccgttta agatacgagt agcccgggtt tccagcaatt cttgcccggc
    17161 aagttgccgt tgtaaccagc gtaccgccag gaagagcata agaatgataa agccaatcgc
    17221 ccccgtgagc ggcgcggtgg tcattaaaga atggaaatag ttgcccatcg gatcctgata
    17281 aaccagacgc agcgacatcc ccggatgctt tatcaacgga acgctcagtt cacgaaacag
    17341 atcgttggtg ccaaccggac gataactacc atttctggcc agggtataaa cctgcttatc
    17401 accatggagc aggtctacac gaacgatatc tgccgacatc attaattcgg taatttgtgg
    17461 ccttaatgtg ctgaagtcat tcgacagtag gtgggtatca atcgccgtcg ccaccgcctg
    17521 aacacgatga ctaaacttat actgaatggc gttgtagaaa cttagcgaac agcccagcaa
    17581 agtcacaaaa attgttaacc cggtgagcag cgtgacaaag gccgaaaatt tcgtcgttaa
    17641 tctcatcctt gtgttaactc cgatagtgag gaagcgggca tactagcaaa tcagatttat
    17701 ctcgcaattt attgcgcttc atcggctttg cttttccatt agcgagtata gtcttcagaa
    17761 attattttcc aatccatcat gcacatgagg accacttatg caggcgttac ttttagaaca
    17821 gcaagacggc aaaactctcg catcagtaca gactctggac gaaagtcgcc tgccggaagg
    17881 cgatgtcacg gttgatgttc actggtcgag cctgaactac aaagatgcgc tggcgattac
    17941 cggtaaggga aaaatcatcc gtaattttcc gatgattcct gggatcgatt ttgccggaac
    18001 tgtacgcacc agcgaagatc cgcgttttca tgccggtcag gaggtgttac tcactggctg
    18061 gggcgttggt gaaaaccact ggggtgggct ggcggaacag gcgcgagtga aaggtgactg
    18121 gctggttgcc atgccgcaag ggctggacgc gcgtaaagca atgattatcg gtactgccgg
    18181 ttttaccgcc atgctgtgtg tgatggcgct ggaagatgcc ggtgttcgcc cgcaggatgg
    18241 ggagattgtc gtgacgggtg ccagtggtgg cgtcggcagt accgccgtgg cgctgctgca
    18301 taagttgggt tatcaggtcg ttgctgtttc cggtcgcgaa agtacccatg aatatctgaa
    18361 aagtttaggt gccagccgta ttcttcctcg cgatgagttt gccgaatccc gtcctctgga
    18421 aaaacaagtc tgggctgggg caattgacac cgttggcgac aaagtgctgg caaaagtgct
    18481 ggcgcaaatg aattacggcg gctgcgtggc ggcctgtggt ctggcgggtg gttttactct
    18541 gccaaccacg gtcatgccat ttattctgcg taatgtccgt ttgcaagggg tggattcagt
    18601 aatgacgcca ccagcacgcc gtgcacaagc ctggcagcga ctggtcaccg atttaccgga
    18661 atcattctat acccaggcgg caaaagagat atctctggca gaggcaccga agtttgccga
    18721 ggccatcatt aataaccaga tccagggtcg cacgctggtg aaggttaact aaccatttag
    18781 cagggaataa taagagaggg aactcatttt gaaatcatta ttcaatcagt taacgggaaa
    18841 agcggttagc cggacagctt tcgtcgaaca tcttggttat gaagttgtac aacatcatcc
    18901 aaactggaaa gtcatgattt cgactgacca taaattgatg cgcattgatg ctccaccaaa
    18961 cagccattat tgatacgcct ccgtcgcctg ttaggtttat ggtgctttgc cttggcgacg
    19021 ctacgcttaa tctgttactg atttctggta ccatgggggg aataatctga ttttatttga
    19081 ttacaaatta accacttaaa cctattgaat gcggagcatt gtcagtcggt taattttgcg
    19141 tgctttagca ttcacatctt tccggacgat gcagtgaaaa ttgggtaatc cccagcaacc
    19201 gctgcgtaat gtcgtctatc ttgtcgcgat cctggcatcc ctacattatt tgtggtctgt
    19261 gaagattatc tcattgcagc ccccatcttc gcagggctgg ctttacagcg tttcacctta
    19321 cgttataaga agttccgtcg atgatggcgc taatttcgtg aattgtgcgg cttgttgcaa
    19381 attacacggt gttgaaggtt atttacatgt tagctgttga ttatcttccc tgataagacc
    19441 agtatttagc tgccaattgc tacgaaatcg ttataatgtg cgacctcgtc ctccctgacg
    19501 cagtttttgc actgcggaaa aggtgacatt ggcgcaacga aggtatattt tgttttttgc
    19561 cggaggatag cagcagatcg ctgcacaatg tccgtcaagt ctaacattga cactctgggg
    19621 caaaatagac cggcgtcccg gcctgctgga atttatcgct atgcatacag ctgtcggggc
    19681 atacgcttta cagacggcgg tgaaacgcct gtcacaatca cactaaacaa agagtacgga
    19741 acccactcat ggatattcgt aagattaaaa aactgatcga gctggttgaa gaatcaggca
    19801 tctccgaact ggaaatttct gaaggtgaag agtcagtacg cattagccgt gcagctcctg
    19861 ccgcaagttt ccctgtgatg caacaagctt acgctgcacc tatgatgcag cagccagctc
    19921 aatctaacgc agccgctccg gcgaccgttc cttccatgga agcgccagca gcagcggaaa
    19981 tcagtggtca catcgtacgt tccccgatgg ttggtacttt ctaccgcacc ccaagcccgg
    20041 acgcaaaagc gttcatcgaa gtgggtcaga aagtaaacgt gggcgatacc ctgtgcatcg
    20101 ttgaagccat gaaaatgatg aaccagatcg aagcggacaa atccggtacc gtgaaagcaa
    20161 ttctggtcga aagtggacaa ccggtagaat ttgacgagcc gctggtcgtc atcgagtaac
    20221 gaggcgaaca tgctggataa aattgttatt gccaaccgcg gcgagattgc attgcgtatt
    20281 cttcgtgcct gtaaagaact gggcatcaag actgtcgctg tgcactccag tgcggatcgc
    20341 gatctaaaac acgtattact ggcagatgaa acggtctgta tcggccctgc tccgtcagta
    20401 aaaagttatc tgaacatccc ggcaatcatc agcgccgctg aaatcaccgg cgcagtagca
    20461 atccatccgg gttacggctt cctctccgag aacgccaatt ttgccgagca ggttgaacgc
    20521 tccggcttta tcttcatcgg cccgaaagca gaaaccattc gcctgatggg cgacaaagta
    20581 tccgcaatcg cggcgatgaa aaaagcaggc gttccttgcg taccgggttc tgacggcccg
    20641 ctgggcgacg atatggataa aaaccgcgcc attgctaaac gcattggtta tccggtgatt
    20701 atcaaagcct ccggcggcgg cggtggtcgc ggtatgcgcg tagtgcgcag cgacgctgaa
    20761 ctggcacaat ccatctccat gacccgtgcg gaagcgaaag cagctttcag caacgatatg
    20821 gtttacatgg agaaatacct ggaaaatcct cgccacgtcg agattcaggt actggctgac
    20881 ggtcagggca acgctatcta tctggcggaa cgtgactgct ccatgcagcg ccgccaccag
    20941 aaagtggtcg aagaagcacc ggctccgggc attaccccgg aactgcgtcg ctacatcggc
    21001 gaacgttgcg ctaaagcgtg tgttgatatc ggctatcgcg gtgcaggtac tttcgagttc
    21061 ctgttcgaaa acggcgagtt ctatttcatc gaaatgaaca cccgtattca ggtagaacac
    21121 ccggttactg aaatgatcac cggcgttgac ctgatcaaag aacagctgcg tatcgctgcc
    21181 ggtcaaccgc tgtcgatcaa gcaagaagaa gttcacgttc gcggccatgc ggtggaatgc
    21241 cgtatcaacg ccgaagatcc gaacaccttc ctgccaagtc cgggcaaaat cacccgtttc
    21301 cacgcacctg gtggttttgg cgtacgttgg gaatctcata tctacgcggg ctacaccgta
    21361 ccgccgtact atgactcaat gatcggtaag ctgatttgct acggtgaaaa ccgtgacgtg
    21421 gcgattgctc gcatgaagaa tgcgctgcag gagctgatca tcgacggtat caaaaccaac
    21481 gttgatctgc agatccgcat catgaatgac gagaacttcc agcatggtgg cactaacatc
    21541 cactatctgg agaaaaaact cggtcttcag gaaaaataat ttgtgacgcg cggtgttttc
    21601 atcgcgctta gcaaagaacg taatcaacgc cgggcctgtt aatgctaccc ggcgttttta
    21661 ttgccgttaa ctaacggtag cctgcaattt ccgctttcaa cgcgctaatt tcagcatcgc
    21721 catcaacaat tcccagctca aagcagtatt tctttgtttc ccctggctca ataaagggca
    21781 gacgcccctg cgctcgttct ttatcacgac cgtcaggaaa actattactg acctccagtc
    21841 ccataacata ttcacccgcg cctaaatttt tccactggat aaagttgggt agctgcatgg
    21901 tgtcgaattt ctcgtaaatt ccccacccca gttcggcgtt caccagcgca actttactca
    21961 tcccctgact gtcgctattc aacgtgagat agtaaacctg ctcgtcaaaa ccgggctgtg
    22021 gggtacaaat ctccagatga ctggttaacc cttccgccgc atgcggagtt cgtggcgtta
    22081 tgcttttagc cgacagcaag atttctgcct gtggcgataa taaaggccag ccgtaattaa
    22141 agtgataaag aatttgcagc ggctggcggg tgaaaccatg attagtcacc ttgtcttcaa
    22201 tgcgcattac attttcgcca taacggcagc gaatggtcct ttccagcgtc agattttcac
    22261 cgaacaatcg tgtttcccgt actttgccat tgatgacaaa ttcaatgctg tcgtcggtcc
    22321 gttctgtgcg ataccccacc tcttctgctg gagtcgcagc caaacgcccg tgtaacccca
    22381 gcgtttctcc ttcatcctca cagggtgtgc caatgtagct aagtccgcag gtagtcagta
    22441 accccgcgta aaagctacgt aaaaacccgt tgccctgaga ctcaaaaaaa gcgggggcga
    22501 caacaccgtt gggggtgata aaagagagcg cagtgtcctt gtagctggcc catgcaatat
    22561 ccagcgcgcg atcttttacc accgtaaatg ccagtcccgc accagtacgg acatcaaacg
    22621 cttctgtacc ctttgctctg ccactacgta actcatagtg tttaattccg gcaacctgcg
    22681 agagatcgcc aatccacgac caaatttcgt ttttcattgt gctgcttccc gaatggacat
    22741 gtcatggcgc tggatgaacg tttcgatttc cataaggcga gacgttccct ccattgggcc
    22801 acgtcgggtt accgccagtg caccgcaggc gttggcatat tgtaatgccc gatgggcgtc
    22861 aaaccctagc tggcggcagg caatccacgc gccaccaaag cagtctcctg caccggtcgg
    22921 gtcaacttct tccaccggat agctctcaac atgaaactgc tcattcgcgg agtagtaact
    22981 ggctccttga ttgccgcgct tcacaatcac ctctttaaca ccttcttcaa gaaaaccagc
    23041 gattgcacgc tccggcgtcg agtgtggcga caagagcaac acttccccct cactgggcat
    23101 atagatatcc gttaactcaa gaacaaagtg gagggcatcg cgcatttctg gaatatcaag
    23161 catttcttta cgaatattcg ggtcgaaaga aataacgcca ccatttgctt taacgatggt
    23221 tactgctttt tttactgcgt ctaccatatg gaatgaaaac agggatgaac ccataatatg
    23281 aaaatgggta caatccttca gaatattttc atcaacatgc tgtgccgata atttaccgca
    23341 agcggcattc ttgatattaa aaataaaatc gcgatcgcca gagttatgat aagtaacaaa
    23401 ggcactaccg gtggcttcca gaggtaagac tgaaatcccc ctgatgtcca caccgtcagc
    23461 agccagacga tgtatattaa tatcaccaaa gccatcattc cccacgcagc taatgatgcc
    23521 gcacggaacg ccaagacgtg tcacctggtc gataaaaata gcgggcgcac cactgggata
    23581 agggccgttc cagatacctg gttgatcaaa tggctggccg attttactcg ccataatttc
    23641 aaccagaatt tctccaattg tgaagacctt actcatatga ttaattcctt gaaatgatta
    23701 gctgcgtttt cttttatttc ttacgtcaaa ataaacggct acaagaatga ctaatccttt
    23761 aaccaccatc tggtaaaaat aaggaacatt cattaagttc atgccattat taataacgcc
    23821 gatggttaat gcgccgatca ccgtccccac cacggttcca tagccgccgt tcaggctggt
    23881 gcctcccagt acagctgcgg caatagcatc cagttcgtag ctcaacgcgg aattcggttg
    23941 cccggaatag aggcgtgagg caaggatcat cccgctgata cctgccagca cggctgtaat
    24001 cataaagact ttaattttca agcgggtgac atttatccct gaataaattg ccgcttcttt
    24061 attaccacca gtgatataaa tttttcgtcc aaaggttgtt ttagtaagaa tgaagtggtt
    24121 tatcagcaat aagatgatta atatccatat aggaataggt atatagagaa attctccatt
    24181 ccccagcgcc agaaaggcat catctttaat catgatgggc ataccatcgg tcactatata
    24241 agcgatacca cggaagatcc ccatagtagc aacggtgaca ataaacgaag ggatccccgc
    24301 tatagccgtc aagccaccat ttatcatccc cagagccagt gctgcaataa tggataatgg
    24361 gaccaataaa acaaatggaa ttccccatga agccccaagc gcagcaaatg tgccaatcaa
    24421 tgcaatggtt gaaccgaccg ataaatcaat atcgccaagc aaaagcacat aagtcattcc
    24481 ataggcggta attgcaatta tcgaaacctg aagaataata ttagtaatgt tattggcggt
    24541 aaaaaaactg tcattaataa aactgaacag aatgattaac accaccattc cactgaggat
    24601 accaccatat tgcctgaaga cttttttaaa attatttgca atgggaattc ccgaaggttt
    24661 cggactggca agagttttct ctgtcattta acgtactcct gttgcagcgg tcattacctg
    24721 tgtctgcgtt aaattttcac atgaataaat atcggcaata gttttattac gcattaccac
    24781 cagacgatcg ctaagtgcca tgacttctgg cagttcagag gacaccagaa taattgctgt
    24841 ccctgccgca gccagttgac gtatcacgtt atagatttca aattttgcgc cgacatccac
    24901 tccgcgcgtt ggctcatcga gcaataaaat acgcggagtt ttctccagcc acttcgataa
    24961 cacgattttc tgttgattac cgccgctcag tgctcccact gcctgatgca cagaactcac
    25021 tttagtgttc attctggcaa ttgattgcag cgtcttcgcc tcttcttgtc ggtgattgat
    25081 gagtcccatc cgcgaagcgt tatattgaaa cgccacatgg tgcgtgttca tattgacgtc
    25141 gtgcatcagc actaaccctt cttccttgcg gttttcggtc acaaaagcaa tgccatgatc
    25201 aatagcctgt ttgggattag cgatcctgac ttccttacca tcaatcaaca cagtcccgtg
    25261 atacgaaacg aggccaaata gcgccttcat cacatcggaa cgcccggccc ccaccaggcc
    25321 aaaaaatccg aggacttccc ccggacgcac agcgaaactg acctctttaa aaagcgaagg
    25381 atgggaaaga ttttttactt ccagttttgc aggaacattt tcatccggtt tttccccaag
    25441 acgtgctggc caaatatttt tcatttcccg accaaccatt tgggcaatca agtgctggat
    25501 atcactgttt ttcttttcat gcgtagcgat atactcaccg tcgcggatca ccgaaatatc
    25561 atctgaaatc cgcataattt catccatgcg atgagagata taaataaccg cacagcctcg
    25621 ctgctttaat ttttcaataa tgttaaacag gatctccgct tcattatcac ttagcgaaga
    25681 tgtcggttca tccataatca cgacatccgc tgcatagctt aaggctttag caatttctac
    25741 cagttgccta tgtgccatcg acatattgcc gaccatttcc agagggtcta gtgggatgcc
    25801 cagttccgcg aggaggttct ggcaatctgc gagcattttt ttatcgttaa tgatgccaaa
    25861 acgtcgcggt tcattattgg cataaatatt ttccgccacg gtcatattat tactcaggct
    25921 cagttcctga aaaataatcg caatccctaa ctggcgagaa tgctgcggat tattaatggt
    25981 gatggtttca ccacgtagtg ttatcgttcc ctgggttggc ggataaacac cggccagtat
    26041 tttcattaat gtcgatttac cggcaccatt ctcgcctaat aaagtatgca cccgcccttt
    26101 acgtaaagag agtgtaatat cttttaatgc ctgaacatga ccaaatgtct tcgcaatatg
    26161 cgaaacatca agaataacat ccgtcataat gacctcggtg tcacaacaaa acgccaataa
    26221 cgttttgttg tgaggtgaag atatttacta tttacctgta taaacgccgg gttgtaccgg
    26281 gatcattttt tctaccggtt taccattgag gtgatcaaca gcggcatcaa tggctttagc
    26341 acccatttga tctggatatt gccgaatcac ggccgcaaac gttttttcac tgtcaacggc
    26401 atcacgcgct tctttcatgc cgtcaaaacc aatgattttg atgttgtcgt tatgcgcaga
    26461 ttttgctgcg ataaccgctg ccagcgccgc atcatcacca aagccaaaca gaccattcag
    26521 gttagcattt gcctgcataa tgttttgcgc agtcgttaac gcttcagctc gcgtaatacc
    26581 aggctgttca gcaacaattt taatatccgg tgtatcgctt aaccctttct taaaaccatc
    26641 aacgcgcgca accaccgatt gtagtgccgg ataagaaata atggctacag tacctttacc
    26701 actcaaaagt ttacccatta acttgcctgc ttcaacgcct cccgcatagt tatcggtcgc
    26761 aacatgcgat acgaccggaa cgccttccgc agcgacgtca acggtgataa cgggaatacc
    26821 ggccttatcg gctttaatta tcgctgcctg gacgcctttc gaatcgaccg gagagataat
    26881 aatggcatcc acttttttag taataaaatc ctcaacatca gaaagttgtt tgtttaaatc
    26941 ctgattggca atagagacac ttaaattgac attgtctttt tttgcctctt ctttcatggc
    27001 attcgcaaga tcaatataga aaggatgttg ttgtgttaat aatgacgcac caattttata
    27061 ctcttttgcc aacgaacttt gcgagaacaa tgccaggctc accaacatag ctgaaccaag
    27121 taatttaata tttttcataa acaatcctca ttatttttgt agggtacaac gtcttaaatt
    27181 tttccttcac taccacaaac gccaataata cgagttacga cttctttcat ggcggccttt
    27241 gcgggctgca tatagtgacg tggatcattt gccgcaggat tgttgtagaa atatcctttt
    27301 aacgcatcgg caaacgcaat tttcaattct gtcgcaacat tcactttaca aataccgcga
    27361 cgaatacagt gctgaacgtc ctgttccgat aagcccgaag caccatgcaa caccagcgga
    27421 atctccactc gctgacgaat ctgttccagc cgcacaaaat ccagtcgtgg ttcatgcgca
    27481 tataaaccat gtgctgtgcc gattgctacc gccagggagt caatttgggt acgttgaaca
    27541 aactctgtag ctgcggctgg cgaggtataa gcggaatctt tttcatccac ccgcagatcg
    27601 tcctcctggc cgccaagacg ccctagctcg gcctcaacgc taacatcaaa gcgatggcaa
    27661 aaggtggtaa cttcttgcac tcgcgcaatg ttgtcttcaa atggcaaatg ggagccatca
    27721 atcatgacag aacggatccc tgcgcgaacc ttgttaaaaa tgtcatcact ctcttcatga
    27781 tggtcgagat gcaggactaa cggcaggttg tactcgcgag ccagcgattg tactaacgaa
    27841 attaaacttc ccacgccacc ataacgatat gtaccgggtg ttcccgccag cataacggga
    27901 gagcgaagtt gtgcagcgct ctcaacaact acctgtaaag tttcaaggtt atgaatgttg
    27961 aaagcaggga cggcatatcc ctctgactgg gcttttttca gcatgttttt gcttgaaata
    28021 atgtacatcg cagctcctgt tatttgtcgt tcgccttaca aaatgaagaa agagaatctt
    28081 cactttcatt ttgaaagcaa actagcacag caaaagcagc aaaaagcgtg atgcatgtcg
    28141 aacatcatca aaataactta caaaaaataa cttaatttat ttttcacttt gcaagtgaac
    28201 ccaatgaaaa ccctgcataa atatgaatat attcatttat ttttcaatgt attaagatat
    28261 tttagctgca attttgaccc atgattttct tttcgaattg tcgatatgat tgaaggataa
    28321 ctttcaaaga aaaatacaag gggctatagt gttacgcatt aaaggccaat gaagagtgtt
    28381 aacgtgccga gaaaatcgtc taacttactg aaacgtagat taaaaattgc agaaattgtt
    28441 gccgcccagg gtgaaatcaa agttgatgac ttatctgcgc aacttggtgt ctctggcgtg
    28501 acgatccgcg gcgatctcag ttatctggag caacagggat atttaaagcg atcatttggc
    28561 ggtgctattg cgacaccact ctcctctgaa ccagaagcga tacaaccgat cgcgccattg
    28621 tctctggcac aacaaatgga aatagcacga cattgcgcac ggttaattcg cgatcgtgac
    28681 acgctatttc ttggacatgg gacaatctgc cgtaagatca ttccattgct cagcgaagtg
    28741 aaaaaactgc gtctgatcac caacgatccc gaacatgcgc tgctggcaaa tcagtttatt
    28801 gatggcgaaa taatactggc tggcagtgaa atgctgcgcc ccgacaccgc actggccgga
    28861 aaacagcttg aacaggcact tcagcatttc accattacac atagcattct ggaaatcagc
    28921 catctggatg ctgatggtac tttaaatatc aacgttccca gactcgccgc tgcctggcag
    28981 ctctgtttcg atcatgccca gaataagacg gttatcgttg ccgccgatcc tgcgccatca
    29041 acggctgcta tcgggcattt gcatcaggca gaaaatgtga tcgtcagccg cagcattaac
    29101 gaacaatatc agcaacaatt gcagtcggct gatttcgtta tcctttatac cagtaatgag
    29161 tgctttacct ggtccaatcg cgaaaggctt caggaatgag aggggttttg tgacaataac
    29221 tatctgcgct atgggcgaat tgctggccga gtttttgtcc cgcaacccac atcaaaaatt
    29281 cactcagcct ggggagttta tcgggccatt tcccagcggt gcgccagcaa tttttgctgc
    29341 tcaggtggca aaactgtccc atcgggccat cttctttgga tgtgttggta atgatgattt
    29401 tgcccgactc attatagagc gtctccgtca tgaaggtgtc attaccgatg ggatccatgt
    29461 tatgaacaat gccgtcacag gtacggcgtt cgtgagttat caaaatcccc agctgcggga
    29521 tttcgtcttt aatatcccta acagcgcctg cggtttgttt actgccgagc acattgataa
    29581 ggatctgctt aaacagtgta accatctgca tattgtgggc tcatcgttgt tctcatttcg
    29641 catgatcgat gtcatgcgta aagcaataac gacgatcaaa tcggctggcg gcaccgtttc
    29701 tttcgatccc aatattcgca aagagatgct gagcattcct gaaatggcgc aggctctcga
    29761 ttatttgatt gaatatacgg atatttttat ccccagcgaa agcgaactcc ctttcttcgc
    29821 gcgtcacaaa aatctgtcag aggaacagat tgttagcgat cttctccacg gcggcgtaaa
    29881 acatgtggcg ataaaacgcg cccagcgtgg ggctagctat tacaagctta aaaacggtac
    29941 attacacgcc cagcatgttg caggtcacga tatcgaaatt atcgatccaa cgggtgcagg
    30001 cgactgcttt ggcgcaacgt ttatcactct tttcttatcc ggtttcccgg cacacaaggc
    30061 gctgcaatat gcaaatgcca gcggcgcgct cgccgtaatg cggcaaggtc cgatggaagg
    30121 gatatcctca ctggcagaca ttgaagactt tttgcagcag cactgaacgg caattttctg
    30181 tcagattatt ttccctgcct gaagacttgc cgtagaattg cccgtttctc gtatcccccc
    30241 atgaggagga ccccttccgt ggacactcgt tttgttcagg cccataaaga ggcgcgctgg
    30301 gcgctggggc tgaccctttt gtatctggcg gtatggttag tagccgctta cttacctggc
    30361 gttgcccccg gttttaccgg ttttccgcgc tggtttgaga tggcctgcat cctgacgccg
    30421 ctgctgttta ttggactgtg ctgggcgatg gtgagattta tctatcgcga tatcccactg
    30481 gaggatgacg atgcagcttg aagtaattct accgctggtc gcctatctgg tggtggtgtt
    30541 cggtatctct gtttatgcga tgcgtaaacg gagcactggc accttcctta atgagtattt
    30601 cctcggcagc cgctctatgg gcggtattgt gctggcgatg acgctcaccg cgacctatat
    30661 cagtgccagt tcgtttatcg gcgggcctgg agctgcttat aaatacggcc tgggctgggt
    30721 attgctggcg atgattcagc ttcctgcagt ctggctttcg ctcggtattc tcggcaagaa
    30781 gttcgcaatt cttgcgcgcc gctacaatgc ggtgacgctg aacgatatgc tgtttgcccg
    30841 ctaccagagt cgtcttctgg tgtggctggc gagtttgagt ttgctggttg cgttcgttgg
    30901 tgcgatgacc gtgcagttta tcggcggtgc gcgcctgctg gaaaccgcgg cgggtattcc
    30961 ttatgaaacc gggctgctga ttttcggtat cagcattgcg ttgtataccg cctttggcgg
    31021 ctttcgcgcc agcgtgctga acgacaccat gcaagggctg gtgatgctga ttggcaccgt
    31081 tgtgctgctt attggcgtgg tacatgccgc aggtggttta agtaatgcgg tagacacgct
    31141 gcaaaccatc gatccgcaac tggttacgcc acaaggcgct gacgatattc tgtcgcctgc
    31201 ctttatgacg tcgttctggg tactggtgtg ctttggcgtt ataggcctgc cgcatactgc
    31261 ggtgcgctgt atctcttata aagacagcaa agcagtacat cgggggatca tcatcggtac
    31321 gattgtagtc gcaatcctga tgttcggtat gcatctggcc ggagcgttag gtcgggcggt
    31381 gatccccgat ctcaccgtac cggatctggt gatcccgacg ttaatggtaa aagtgctgcc
    31441 accgtttgcc gccgggatct tcctggctgc accgatggct gcgatcatgt cgacaattaa
    31501 cgcccaactg ctgcaaagtt ccgctacgat cattaaagat ctctatctga atatccgtcc
    31561 ggatcaaatg caaaacgaga cgcgtctgaa gcggatgtcg gcggtgatca cgttggttct
    31621 cggtgcgttg ctgctgcttg ccgcctggaa gccgccagaa atgatcatct ggctgaattt
    31681 gctggccttc ggtgggctgg aagccgtttt cctgtggccg ctggtgctgg gtctttactg
    31741 ggaacgcgcc aacgccaaag gcgcgctaag tgcgatgatc gttggcggcg tgctgtatgc
    31801 cgtactcgcg aagctgaata ttcagtacct gggcttccac cctatcgtgc cctcgttact
    31861 actaagtttg ctggctttcc tggtcggaaa ccgtttcggt acatccgtcc cgcaagctac
    31921 cgttttgact actgataaat aaagagtttt gccatgcctt ggatccaact gaaactgaac
    31981 accaccggcg caaacgcgga agatcttagc gatgcgctga tggaagcggg tgccgtttct
    32041 atcacttttc aggataccca cgatacgcca gtatttgagc cgctgccggg cgaaacgcgc
    32101 ctgtggggcg acaccgatgt gattggtctg ttcgacgctg aaaccgatat gaacgacgtg
    32161 gtggcgattc tggaaaacca tccgctgctc ggcgcgggct tcgcgcataa aatcgaacaa
    32221 ctggaagata aagactggga gcgcgaatgg atggataatt tccacccgat gcgctttggt
    32281 gaacgactgt ggatctgccc aagctggcgt gatgtgccgg acgaaaacgc cgtcaacgtg
    32341 atgttagacc cagggctggc gtttggtacg ggtacccatc caactacctc tctgtgcctg
    32401 caatggctcg acagcctcga tttaaccggt aaaacagtca tcgactttgg ctgcggttcc
    32461 ggcattctgg ctatcgcggc gctgaaactg ggtgcagcaa aagccattgg tattgatatc
    32521 gatccgcagg cgatccaggc cagccgcgat aacgccgaac gtaatggcgt ttctgatcgt
    32581 ctggaactct acttaccgaa agatcagcca gaagaaatga aagccgacgt ggtggtcgct
    32641 aacatccttg caggcccatt acgtgaactg gcaccgttaa tcagcgtcct gccagtttca
    32701 ggcggtttgc tgggcctttc cggtattctg gcaagccagg cagagagcgt ttgcgaagct
    32761 tatgccgaca gcttcgctct ggacccggtc gtggaaaaag aagagtggtg ccgcattacc
    32821 ggtcgtaaga attaaccttc gcatcgccgt atggcgacgc agagcgaagt gcgagcgatg
    32881 tcacaaaagg cacgttaatt tgccgattat ttacgcaaat ttgcgtgcca aaattttcat
    32941 tcataaagaa aaattgagaa cttactcaaa tttctttgag tgtaaatttt agtcactatt
    33001 ttctaatatg atgattttta tgagtaatta tcgcgctacg ctcattttaa atgcaattct
    33061 ttgatccatc tcagaggatt ggtcaaagtt tggcctttca tctcgtgcaa aaaatgcgta
    33121 atatacgccg ccttgcagtc acagtatggt catttcttaa ctcatgcgca tcggacaata
    33181 tcagctcaga aatcgcctga tcgcagcgcc catggctggc attacagaca gaccttttcg
    33241 gacgttgtgc tacgagatgg gagccggatt gacagtatcc gagatgatgt cttctaaccc
    33301 acaggtttgg gaaagcgaca aatctcgttt acggatggtg cacattgatg aacccggtat
    33361 tcgcaccgtg caaattgctg gtagcgatcc gaaagaaatg gcagatgcag cacgtattaa
    33421 cgtggaaagc ggtgcccaga ttattgatat caatatgggt tgcccggcta aaaaagtgaa
    33481 tcgcaagctc gcaggttcag ccctcttgca gtacccggat gtcgttaaat cgatccttac
    33541 cgaggtcgtc aatgcagtgg acgttcctgt taccctgaaa attcgcactg gctgggcacc
    33601 ggaacaccgt aactgcgaag agattgccca actggctgaa gactgtggca ttcaggctct
    33661 gaccattcat ggccgtacac gcgcctgttt gttcaatgga gaagctgagt acgacagtat
    33721 tcgggcagtt aagcagaaag tttccattcc ggttatcgcg aatggtgaca ttactgaccc
    33781 gcttaaagcc agagctgtgc tcgactatac aggggcggat gccctgatga taggccgcgc
    33841 agctcaggga agaccctgga tctttcggga aatccagcat tatctggaca ctggggagtt
    33901 gctgcccccg ctgcctttgg cagaggttaa gcgcttgctt tgcgcgcacg ttcgggaact
    33961 gcatgacttt tatggtccgg caaaagggta ccgaattgca cgtaaacacg tttcctggta
    34021 tctccaggaa cacgctccaa atgaccagtt tcggcgcaca ttcaacgcca ttgaggatgc
    34081 cagcgaacag ctggaggcgt tggaggcata cttcgaaaat tttgcgtaaa cagaaataaa
    34141 gagctgacag aactatgttc gaacaacgcg taaattctga cgtactgacc gtttctaccg
    34201 ttaactctca ggatcaggta acccaaaaac ccctgcgtga ctcggttaaa caggcactga
    34261 agaactattt tgctcaactg aatggtcagg atgtgaatga cctctatgag ctggtactgg
    34321 ctgaagtaga acagcccctg ttggacatgg tgatgcaata cacccgtggt aaccagaccc
    34381 gtgctgctct gatgatgggc atcaaccgtg gtacgctgcg taaaaaattg aaaaaatacg
    34441 gcatgaacta attcaggtta gctaattgct tgattaaaag gcgctactcg gcatggggaa
    34501 gcgccttttt tataggtgtc acaaagggag tgaccatgag aacaggatgt gaaccgaccc
    34561 gatttggtaa tgaagcaaag accatcatcc agggtgatgc attaaccgaa cttaaaaagc
    34621 tccccgccga aagtgtcgat ctgatctttg ccgacccacc gtataacatc ggtaaaaatt
    34681 ttgatggtct gatcgaagcc tggaaagaag atctgtttat cgactggctg tttgaagtga
    34741 ttgcagagtg ccatcgcgtt ctgaaaaagc agggcagcat gtacatcatg aatagcacgg
    34801 aaaacatgcc ctttatcgat ctccagtgcc gcaagctttt taccatcaaa agtcgcatcg
    34861 tctggtcata tgacagttct ggagtgcagg cgaaaaaaca ctacggctcc atgtacgaac
    34921 ccatcctgat gatggtgaaa gacgcaaaga actacacgtt caacggtgat gctattctgg
    34981 tagaagccaa aaccggatcg cagcgcgcgt tgatcaatta tcgcaaaaat cctccacagc
    35041 cttacaatca tcaaaaagta ccgggtaacg tctgggattt tccgcgcgtg cgttatttga
    35101 tggatgaata tgaaaaccac ccgacgcaaa aaccggaagc cttgctgaaa cgcattattc
    35161 tcgcctcttc caacccaggc gatatcgttc tcgacccgtt tgccggtagc tttactaccg
    35221 gtgccgtagc cgtcgccagc gggcgaaaat tcattggtat tgagatcaac agcgagtaca
    35281 tcaaaatggg gcttcgacgg ctggatgtcg cgtcgcatta ctctgcggaa gaactggcga
    35341 aagtgaaaaa aagaaagacc ggcaacctgt caaaacgaag ccggttaagc gaagttgacc
    35401 ccgatctcat tgcaaagtaa aggaagtgta agcctggttt tcagattatt catttcgtgt
    35461 atatttcctg ccagacttgg ttaaacatgc acaggctcag gtaatgattc gcaagtattg
    35521 gtggctcgtc gttttcgctg tcttcgtttt tctgtttgat actttactga tgcagtggat
    35581 tgaactgctg gcaacagaaa cagacaaatg ccgcaatatg aactcagtta atccactaaa
    35641 actggttaac tgtgacgaac tgaattttca ggacagaatg tgaatttata tgacacttaa
    35701 ttcattcgtt ttatgaatta atttcgttat gttttcatct ggcatgaaca ttcttaatac
    35761 gttatcgacc agagcggggg cttgtttata aagatcataa cccgccatat tcattaacca
    35821 gttttgaaca attccgctga aggcaccatc aataataatc atcacaacat ctaaatcgag
    35881 attatttgct acacaacctt gttgctgaca cgcctgcaat acttcgcgga gagtctgcgg
    35941 attaaagccc atcttttcgc gtatcactcc ctcggccagc atctcatcat taaattcaca
    36001 tttgtgatat aagattttca gcaacgcctg ctggcgggga attttggcaa tatattgcaa
    36061 accgacaatc aatttttcac gcaattgctg aaacgggtca tgctctaacc cagcggtcaa
    36121 gtgatcctgg attaactccc gcaatgaagg ctgttgcaac cacatctcat taaacagttg
    36181 agtcttgttt tcgaagtgcc agtagatagc gccacgcgta acgttagcag cgtcggcaat
    36241 gtcgttgagc gtcgtcttgc ttacgccatg ctgcgcaaac tgggcgatgg cagtttcaat
    36301 cagttcttgc cgggtcttca gggcttcagc tttggttctt tttgccatga ttaattattc
    36361 aggaaataaa tatattcgac acaggatgag aaaatagcga aggttaatct atcacctaat
    36421 gtgtatttat acgagaggct aatattgcgt tgctataaat cgtcaaataa atgatatgta
    36481 ttatttacat aaaatacatt cacttgacct atacatattt caatttacga gattttaatt
    36541 ctatttcttt cattccgcgt caaaacaaaa cagtagaata ttaatctttt tttgtgttta
    36601 tgtgccttga gttgccagta ttcataacta ttccttacat cgacgaatga taatttgtag
    36661 gatagcgaac tgtatttttc tttctgcgag ttaacgcatt gcctttttgg gcaaataacg
    36721 cgcttttggt tttttgagga atagtaatga cgaaacatgc caggtttttc ctcctgccct
    36781 cctttattct gatctccgcg gctttaatcg ccggttgtaa cgataaggga gaagagaaag
    36841 ctcacgtcgg tgaaccgcag gttaccgttc atattgtgaa aacggccccg ttagaagtta
    36901 agactgaatt accaggccgc accaatgctt accgtatagc cgaagttcgc ccacaggtta
    36961 gcgggatcgt actgaatcgc aatttcactg aaggcagcga tgtgcaagca ggccagtccc
    37021 tgtaccagat cgatcccgcg acctatcagg caagttatga cagcgcgaaa ggcgaactgg
    37081 cgaaaagtga agccgccgcc gccatcgcgc atttgacggt aaaacgttac gttccgctcg
    37141 tgggtacgaa atacatcagt cagcaggagt acgaccaggc cattgctgat gctcgccagg
    37201 ccgatgccgc cgtgattgcc gcaaaagcca cagtcgaaag cgctcgcatc aatctcgctt
    37261 ataccaaagt gactgcgcca attagcggac gtatcggcaa atcgaccgtg accgaaggcg
    37321 ctcttgtcac taatgggcaa acgactgaac tggcgactgt ccagcagctc gatcctatct
    37381 acgttgatgt gacccaatcc agcaacgatt ttatgaggct gaagcaatcc gtagagcaag
    37441 gaaatttgca taaggaaaac gccaccagca acgtagagtt ggtcatggag aacggtcaaa
    37501 cctatcccct gaaaggtacg ctgcaattct ccgatgtgac cgttgatgaa agcaccggct
    37561 ccataaccct acgtgctgtc ttccctaacc cgcaacatac gcttttgccg ggtatgtttg
    37621 tgcgcgcacg gattgatgaa ggcgtccaac ctgacgccat tcttatcccg caacaaggcg
    37681 ttagccgcac accacgtggt gatgcaaccg tgctgattgt taacaataaa agtcaggttg
    37741 aagcgcgccc tgtcgttgcc agtcaggcga ttggcgataa atggttgatt agcgaaggtc
    37801 tgaaatctgg cgatcaagtc attgtcagcg gcctgcaaaa agcgcgtccg ggagagcagg
    37861 ttaaagccac taccgatacc cccgcagata ctgcatcgaa gtaaggcaat ctgacatggc
    37921 aaactttttt attcgacgac cgatatttgc atgggtgctg gccattattc tgatgatggc
    37981 gggcgcactg gcgatcctac aattgcccgt cgcccagtat ccaaccattg cgccgcctgc
    38041 ggtttctgtt tcggcaaact atccgggtgc tgatgcgcag accgtgcagg atacagtgac
    38101 gcaggttatc gaacagaata tgaacggtat cgataacctg atgtatatgt cctccaccag
    38161 cgattccgcc ggtagcgtga caattaccct taccttccag tccgggaccg atcctgatat
    38221 cgcgcaagta caggtgcaga acaaactcca gctcgccacg ccgttgctgc cgcaggaggt
    38281 tcagcagcag gggatcagtg ttgaaaagtc cagtagcagc tatttgatgg tggcgggctt
    38341 tgtctctgat aaccctggca ccacacagga cgatatctcg gactatgtgg cctctaacgt
    38401 taaagatacg cttagccgtc tgaatggcgt cggtgacgta cagcttttcg gcgcacagta
    38461 tgcgatgcgt atctggctgg acgccgatct gctaaacaaa tataaactga caccggttga
    38521 tgtgattaac cagttgaagg tacagaacga tcagatcgct gccggacagt tgggcggaac
    38581 gccagcgtta ccagggcaac agttgaacgc ctcgattatt gctcagacgc ggttaaaaaa
    38641 tccggaagaa ttcggcaaag tgaccctgcg cgtaaacagt gacggctcgg tggtgcgtct
    38701 gaaagatgtc gcacgggttg aacttggcgg tgaaaactat aacgttatcg ctcgcatcaa
    38761 cggaaaaccg gcggcgggcc tggggattaa gctggcaacc ggcgcgaatg ctctcgatac
    38821 tgcgaaagcc attaaggcaa aactggcgga attacagcca ttcttcccgc agggaatgaa
    38881 ggttctttac ccttatgaca ccacgccttt cgtccagctt tctatccagg aagtggtgaa
    38941 aacgctgttc gaagccatta tgctggtgtt cctggtgatg tatctgttct tgcagaacat
    39001 gcgggcaaca ttgataccca ccattgctgt acctgtcgtg ttgttaggga catttgccat
    39061 actcgccgct tttggttact ccatcaatac gctaacgatg tttgggatgg tacttgccat
    39121 cggacttctt gttgatgatg cgatagtcgt tgtggagaac gtcgagcgcg taatgatgga
    39181 ggataaactc ccccccagag aagcgacgga aaaatcgatg tcgcaaatcc agggcgcgct
    39241 ggtaggtatc gcgatggtac tgtcggcggt atttattccg atggcattct tcggtggctc
    39301 aacaggggca atttatcgcc agttctctat cactattgtt tcagcaatgg cgctttcagt
    39361 actggttgcg ctgattctca cccccgcgtt atgtgcaaca ttgctgaaac cagtctctgc
    39421 cgagcatcac gaaaataagg gaggattctt cggctggttt aacaccactt tcgatcatag
    39481 cgttaatcac tacaccaata gcgttggcaa aatcctcggt tccacagggc gatatttact
    39541 gatctatgcg ctgattgttg caggaatggt ggtgttgttt ttacgtcttc cgtcttcctt
    39601 cttacctgaa gaggatcagg gtgtctttct gaccatgatt cagttacccg ctggcgcgac
    39661 gcaagagcgg acgcaaaaag tgttggatca agtgacggat tactatctga agaacgagaa
    39721 agcgaacgtt gaaagtgtct ttacagttaa cggctttagc ttcagcggcc aggcacaaaa
    39781 cgccggtatg gccttcgtca gtctgaaacc gtgggaagag cgtagtggtg acgaaaacag
    39841 tgcggaagca gtaatccatc gtgccaaaat ggaattgggc aagatccgcg acggttttgt
    39901 cattccattt aatatgccag ccattgttga actaggcacg gcaacgggtt tcgactttga
    39961 gttaattgat caggctgggc tgggtcacga tgccctgacc caggcccgta accagttgct
    40021 tggcatggcg gcgcaacatc ctgccagctt agtcagcgtg cgccctaatg gcctggaaga
    40081 caccgcgcag tttaaactgg aagttgacca ggaaaaggcg caggcattag gtgtttcact
    40141 ttctgacatc aatcagacca tttcaacggc gttgggtggg acttacgtta acgacttcat
    40201 cgaccgtggt cgcgtgaaaa aggtgtatgt tcaggcggat gccaaattcc gtatgctgcc
    40261 agaagatgtc gataaacttt atgtccgcag cgccaacggc gaaatggtgc cattctctgc
    40321 ctttaccact tcacattggg tgtatggctc tccgcgactg gaacgctaca acggtctgcc
    40381 gtcaatggag attcaggggg aagccgcgcc aggaaccagt tccggcgatg ctatggcgtt
    40441 gatggaaaac cttgcgtcaa aattaccggc gggcattggt tatgactgga cgggtatgtc
    40501 atatcaggaa cgtttatcgg gaaaccaggc tcccgctctg gtagcaattt cctttgtggt
    40561 tgttttcctg tgccttgctg cactctatga aagctggtca attcctgtct cggttatgtt
    40621 ggtcgtgccg ttagggattg tcggcgtgct actggcggca acactcttta atcaaaaaaa
    40681 tgacgtctac tttatggtgg gcttgctaac gacaattggc ttgtcggcca aaaacgctat
    40741 tttgattgtt gagttcgcta aagatctcat ggagaaagag ggtaaaggtg ttgttgaagc
    40801 gacactaatg gcagtacgta tgcgcctgcg tcctatcctg atgacctctc tcgcctttat
    40861 tctcggcgta ttaccgctag ctatcagtaa cggtgccggc agtggcgcgc agaacgcagt
    40921 gggtatcggg gtaatgggcg ggatggtttc tgcaacgttg ctggcaatct tcttcgtgcc
    40981 ggtgttcttt gtggtgatcc gccgttgctt taaaggataa atcagaaaca taaaggcact
    41041 ttcgggtgcc tttattattt ccagtgaaac ccataaaaat taataagata ttcctctact
    41101 cactttttaa aaactttcta tagttcccgc tcccttcact atttttacaa ttcacataat
    41161 ttgtcattat tcattccgca agatttataa cctccagtga taaaatggca ttcagctcgt
    41221 taataagaga gttaacttat taagcgttag cgtttattac tgaggtaaca ccatgaaaag
    41281 attaattcct gtggcattgc tcaccgcatt gctggcgggc tgtgctcacg attcgccctg
    41341 cgttccggtt tatgacgatc agggtcgact ggttcacact aatacctgta tgaaaggcac
    41401 gactcaggat aactgggaaa cggctggggc tattgccggc ggggcagcag ctgttgctgg
    41461 cctgacgatg gggatcatcg ctctgtcgaa ataactaaac agggcgcgga gctccgcgct
    41521 ctttttaacg atacagtatc tttccataag ataaaatatt gctatattct gctgggtaat
    41581 tccctgctga tttagcatgt tatatcacgt tatttcgctg ctttcgaaat aacgcatcaa
    41641 tttaactttc acacttccca ccagaaatat actcacgcta acaatcatta ttctgcttag
    41701 taaaaaacgc gtaaatattt tgcgccaaaa tgtggcgcat gtttcatttt cgcaccatta
    41761 cgaggcgctg tttttattat ttcctgtcta cactcagctt attgcgacgc gaaatcgtgc
    41821 gcaaaagctg gcactacttt tgcttataag aggatggcca cagacaggta aaagacgttt
    41881 cccaaacgtc ctataacgat aattttcgcc tcacaggaag cattatgaaa aagatgatga
    41941 tagccacact ggctgccgcc agcgtgctgc ttgccgttgc aaatcaggcg catgctggcg
    42001 cgacgcttga tgccgttcag aaaaaaggtt ttgtgcaatg cgggatcagt gatggattac
    42061 ctgggttctc ttatgccgat gctgacggta agttttcagg tattgatgta gatgtttgtc
    42121 gtggtgttgc cgctgctgta ttcggtgacg atacgaaagt gaaatatacc ccgctcactg
    42181 caaaagaacg cttcaccgct ttacagtcag gggaggtgga tttgctctcc cgtaatacga
    42241 cctggacttc atctcgcgat gccgggatgg gaatggcatt tactggcgtc acttattacg
    42301 acggcattgg cttcctgacg cacgataaag cggggctaaa aagcgcgaaa gaactggatg
    42361 gcgctaccgt ctgtattcag gcggggactg ataccgaact caacgtcgcc gattacttca
    42421 aggcaaataa tatgaagtac acgccagtaa ccttcgatcg ctcagacgaa tcagcgaagg
    42481 ctctggaatc tggccgctgt gatactctgg cctcggatca atcacaactg tatgccctac
    42541 gcatcaaatt aagcaaccca actgaatgga ttgtcttacc ggaagttatc tctaaagaac
    42601 cacttgggcc ggtagttcgt cgtggcgatg atgaatggtt ctcgattgta cgctggacgc
    42661 ttttcgccat gctgaatgct gaagagatgg gcatcaattc ccagaatgtc gatgaaaaag
    42721 cggctaatcc agcaacgcct gatatggcac atctgctggg taaagaaggc gattacggca
    42781 aggatctgaa gctggataat aaatgggcct ataacatcat caaacaggtg ggtaactact
    42841 cggaaatttt cgagcgtaac gtaggttcag aaagcccgct gaaaattaaa cgtgggcaaa
    42901 ataatctctg gaataacggc ggtattcagt acgcgccgcc cgtgcgttaa gtcggtgtga
    42961 ggtaacgagc gttgctacgg cggcgctctt ttcagcgtta tggttttcga ggtttctatg
    43021 ccccatcgcc gctcaaccgt taaaggctca ctctcttttg ccaaccctac ggttcgcgcc
    43081 tggttattcc agatccttgc cgttgttgct gctgtcagca ttgttggttg gttatttcac
    43141 aacactgtaa cgaatctcag taatcgtggc ataacatcag gatttgcttt tcttgaccgc
    43201 ggggccggtt ttggcatcgt tcagcatttg attgattatc agcaaggcga cacttacgga
    43261 cgcattttta ttgtcggcct actcaatacg ctactggttt ctgcattgtg tattgtgttc
    43321 gcttctgttt tgggcttctt tatcggtctg gcgagacttt cggataactg gctgctacga
    43381 aagctttcca caatttatat tgagatcttc cgtaatattc ccccgctgct gcaaatcttc
    43441 ttctggtact ttgccgtgtt gcgcaatttg cccggaccac gacaggcagt gagcgcgttt
    43501 gacctggcct ttttgagcaa tcgtgggctt tatattccgt cgccgcagct gggagacgga
    43561 tttattgcgt ttatcctggc tgttgttatg gctatagtcc tttctgttgg gctattccgc
    43621 tttaataaaa cataccagat aaagaccgga caactgcgcc gcacctggcc attcgccgct
    43681 gtgttgatca ttggtttgcc tttactggcg caatggcttt ttggcgcagc actacactgg
    43741 gatgtcccag cccttcgagg ctttaatttc cgcggcggga tggttttaat tcctgaactg
    43801 gcagccttaa cgctagcact ttcgatttat acctctgcat ttatcgccga gattatccgc
    43861 gcagggatcc aggcagtgcc ttatggtcaa catgaagcgg ctcgatcact gggattaccc
    43921 aacccggtta cgctacgcca ggtcattatt ccccaggcat tgcgggtgat tattccaccg
    43981 ttaaccagcc agtatctcaa catcgtcaag aactcctctc ttgccgccgc tattggctat
    44041 cccgatatgg tttcgctgtt tgctggcacc gtgctgaacc aaacggggca agccatcgag
    44101 acgatagcca tgaccatgtc ggtctatctg attatcagcc tgactatctc gctgctgatg
    44161 aatatctata accgccgcat cgcgatcgtt gaacgctaag gagtcatgat gacaaaagta
    44221 ttgctgtctc atcccccgcg cccggcgagc cataactcaa gccgcgcgat ggtgtgggtg
    44281 cgaaaaaatc tgttctccag ctggagcaat agcctgctga ctattggctg catatggttg
    44341 atgtgggaac tgatcccacc gttgctgaac tgggcatttt tgcaggctaa ctgggttggc
    44401 tcaacgcgtg ccgactgcac aaaagccggt gcctgttggg tcttcatcca cgaacgattt
    44461 ggtcagttta tgtatggact ttacccacac gaccaacgct ggcgaattaa cctggcatta
    44521 ctgattggcc ttgtgtctat cgcaccaatg ttctggaaaa tacttccgca tcgcggtcgc
    44581 tatattgcgg tctgggcggt gatttaccca ctggttgtct ggtggctgat gtatggtggg
    44641 tttcttggtc ttgatcgggt tgaaacccgg caatggggcg ggttgacgct aactttaatt
    44701 attgcatcag ttgggattgc gggggcgcta ccgtggggga tcttactggc gttaggtcgc
    44761 cgctcccata tgccgattgt gcgtatctta tcggtcattt ttatcgagtt ctggcgcggc
    44821 gtaccgctga ttaccgtatt gtttatgtct tcggtcatgc tgccgttgtt tatggcagaa
    44881 ggcaccagta tcgataaact gatccgcgcg ctggttggcg tgatcctgtt tcagtcagca
    44941 tatgttgcgg aagtcgtgcg aggcggatta caggcgctgc ctaaagggca atatgaagcg
    45001 gcagagtcgc tggcattggg ttattggaaa actcaggggc ttgttattct gccccaggcg
    45061 ttgaagctgg taattcctgg gctggtaaat accatcatcg cactcttcaa agataccagt
    45121 ctggtgatca tcatcgggtt gttcgatctt ttcagtagcg ttcagcaggc aaccgttgat
    45181 cccgcgtggt tgggtatgtc gacggaaggg tatgttttcg ccgcgctgat ctactggatc
    45241 ttctgtttca gcatgtcacg ttatagccaa catctggaaa aacgttttaa caccgggcgt
    45301 acaccgcatt gaggacacta tgagccaaat tttactgcaa cctgctaacg cgatgattac
    45361 gctggaaaac gtcaataaat ggtatggaca attccatgtt ttgaaaaata taaatttaac
    45421 cgtgcaaccg ggcgaacgga tcgttctatg tggcccttca ggttccggta aatcaacaac
    45481 cattcgttgt attaatcatc tggaagaaca tcaacaggga cggatcgtgg tagatggcat
    45541 cgaacttaat gaagatatcc gcaatattga gcgcgtcagg caggaagtgg gaatggtctt
    45601 tcagcatttc aatctcttcc ctcatctgac cgtgttacag aactgtaccc tggcaccgat
    45661 ttgggtacgc aagatgccaa agaaagaggc tgaagctctg gcgatgcatt accttgagcg
    45721 ggtgagaatt gccgaacatg cccagaagtt tcccggacag atttctggtg gtcagcagca
    45781 acgtgttgcc atagcacgtt cgctgtgtat gaagccgaaa attatgttgt ttgatgagcc
    45841 aacgtcggcg ctcgatcctg agatggtgaa agaggtgctg gatacgatga ttgggctggc
    45901 gcagtcgggt atgacaatgt tgtgtgtaac acatgagatg gggtttgcac gaaccgtcgc
    45961 tgaccgggtg atttttatgg atcgtgggga aatagtggag caagctgcac ctgatgaatt
    46021 ttttgcgcat cctaaatcag agcgtacgag ggcattttta tcgcaggtaa tccattaatt
    46081 gaatattagt tcgaaaagca aaaaggccat cctttcggat ggcctttcgc ctgatttgat
    46141 gtctggcagt tccctactct cgcatgggga gaccccacac taccatcggc gctacggcgt
    46201 ttcacttctg agttcggcat ggggtcaggt gggaccaccg cgctactgcc gccagacaaa
    46261 ttcttttcta atctgccgaa ctttaaccta aaaagtggtg ctgataccca gagtcgaact
    46321 ggggacctca cccttaccaa gggtgcgctc taccaactga gccatatcag cacgct
//
LOCUS       DAFGPF010000027        46189 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFGPF010000027 DAFGPF010000000
VERSION     DAFGPF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46189
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.027"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            184..1518
                     /gene="adeQ"
                     /locus_tag="LSX49_001723"
                     /gene_synonym="yicO"
     CDS             184..1518
                     /gene="adeQ"
                     /locus_tag="LSX49_001723"
                     /gene_synonym="yicO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeQ"
                     /protein_id="HBL7168146.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGVFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALSLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDSNGKFPNMNKALYVDSISSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTA
                     VVVGVMFLLVMFFSPLVAMVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITT
                     VMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD"
     gene            1571..2023
                     /locus_tag="LSX49_001724"
     CDS             1571..2023
                     /locus_tag="LSX49_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HBL7168147.1"
                     /translation="MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            complement(2139..2462)
                     /locus_tag="LSX49_001725"
     CDS             complement(2139..2462)
                     /locus_tag="LSX49_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBL7168148.1"
                     /translation="MTAKTKFKSPAFEAIHSAAAGLSRVDAISAETMRTFDKACLTSV
                     QDLQPVEIKALREKLKVSQPVFAHYLNTSVSTVQKWESGAKRPNGISLKLLSIVQKHG
                     LEVLL"
     gene            complement(2446..2799)
                     /locus_tag="LSX49_001726"
     CDS             complement(2446..2799)
                     /locus_tag="LSX49_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL7168149.1"
                     /translation="MFKTKWFAREARSHAITDEELCRAILETEQGKADVLGGGVFKKR
                     LHRNRERAIILAKGGSNWFYTFLYAKQDMSNINSQELAGFRELAKHYAFLTKAQLTAM
                     INTKELTEICYDCKN"
     gene            3033..4223
                     /gene="nepI"
                     /locus_tag="LSX49_001727"
     CDS             3033..4223
                     /gene="nepI"
                     /locus_tag="LSX49_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HBL7168150.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFVGTSLSSFIL
                     KRSVKLALAGAPFVLALSALVLTLWGSDKIVATGVAIIWGLTFALIPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MKKS"
     gene            complement(4264..4557)
                     /locus_tag="LSX49_001728"
     CDS             complement(4264..4557)
                     /locus_tag="LSX49_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168151.1"
                     /translation="MKPTMLLMITIFLIFPAISQAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDESNKQHIREAIVAMERNNQSNYWEALGKVECPDM"
     gene            4779..5597
                     /gene="nlpA"
                     /locus_tag="LSX49_001729"
     CDS             4779..5597
                     /gene="nlpA"
                     /locus_tag="LSX49_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HBL7168152.1"
                     /translation="MKLTTHHLRAGAALLLAGVLLAGCDQSSSDEKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVNDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW"
     gene            complement(5601..6524)
                     /locus_tag="LSX49_001730"
     CDS             complement(5601..6524)
                     /locus_tag="LSX49_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBL7168153.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLIGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISMDSRRRARKINRPARHE"
     gene            complement(6702..7199)
                     /locus_tag="LSX49_001731"
     CDS             complement(6702..7199)
                     /locus_tag="LSX49_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020237521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168154.1"
                     /translation="MGHGTCKAANSARHLIESKEKNRSSRVKVFSTHINLSHPAASWL
                     ATQTCANNIFNLFQNNNALYLFENDNKIELRMGHDSFFSIETIDKINKENIKGIKLKN
                     ETTYVSLPNPTILITTTSTPERQFSISVLDDDNKENLPTDTAPCFIIGIPDEYTKAIE
                     LLNIK"
     gene            complement(7769..8806)
                     /locus_tag="LSX49_001732"
     CDS             complement(7769..8806)
                     /locus_tag="LSX49_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HBL7168155.1"
                     /translation="MSDKDLTQPPAGEFIMFASGDGRVRVECRFESDTIWLSQAAMAE
                     LYDKDVRTINEHLINIFSEGELVQNSTIRKFRIVRQEGKRQVSREIDHYNLEAILAVG
                     YRVRSPRGTQFRQWATQTLQEYLIKGFVMDDERLKNPPVGSSVVPDYFDEMLERIRDI
                     RASERRVYLRVREIFALAADYQPSLKETTQFFQTIQNKLHFACTGHTAAELIHKRADA
                     SQPHMGLTSYKGEEVRKGDVTVAKNYLTQDEVSELNRVVNMWLDFAEDQARRRQQVFL
                     RDWQDKLDQFLQFNDREVLQGAGKISKKMADEKAQAEYVQFAEQQRRLKEAEGEKDIA
                     GLLQWNKESKK"
     gene            complement(8859..8953)
                     /locus_tag="LSX49_001733"
     tRNA            complement(8859..8953)
                     /locus_tag="LSX49_001733"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8917..8919),aa:Sec,seq:tca)
     gene            9246..10628
                     /locus_tag="LSX49_001734"
     CDS             9246..10628
                     /locus_tag="LSX49_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HBL7168156.1"
                     /translation="MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSMNGKMIYAAITYTLLTLLYTIVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMR
                     DDLRDIWQNDQWRIVGFLTIFNILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASITMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDA
                     AEKAQNSATISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQ
                     QQFTSQEVQN"
     gene            10638..12956
                     /gene="yicI"
                     /locus_tag="LSX49_001735"
     CDS             10638..12956
                     /gene="yicI"
                     /locus_tag="LSX49_001735"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HBL7168157.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEQQGNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYVTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHSFLSLPVYVRDSTLLALGNNDQRPDYAW
                     HEGTAFHLFNLQDGHEAVCEVPTADGSVIFTLKAARTGNTITVTGTGEAKNWTLCLRN
                     IVKVNGLQGGSQAESEQGLVVTPQGNALTITL"
     gene            13251..14804
                     /locus_tag="LSX49_001736"
     CDS             13251..14804
                     /locus_tag="LSX49_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL7168158.1"
                     /translation="MQMITSRQNRLLRFLLPRREYTTIVTIAGYLNVSEKTIQRDLRL
                     LEQWLGQWRINVEKRAGAGVMLSAENIADLLHLDHLLVAECEEIDGVMNNARRVKIAS
                     QLLSETPNETSISKLSERYFISGASIVNDLRVIESWLAPLGLSLIRSPSGTHIEGSEG
                     QVRQAMALLINGIINHNEPQGVVYSRLDPGSYKALVHYFGEEEVLFVQSLLLDIENEL
                     SWSLGEPYYVNIFTHILIMMYRNTHGNALSREEDQTRQYDENIFNVASQMIHKIEQRI
                     AHTLPDDEVWFIYQYIISSGVAIDGQKDVSIISHMQASNEARLITWRLITVFSDIVDC
                     DFSEDSALYDGLLVHIKPLINRLNYRIHIRNPLLEDIKAELADVWRLTQYVVNQVFKT
                     WGENAVSEDEVDYLTVHFQAAMERQIARKRVLLVCSTGIGTSHLLKSRILRAFPEWTI
                     VDVISAANLSQVLPDNIELIISTINLPTVTMPVAYVTAFFNDADIKRVTEMVITEKLH
                     HATSRVVEI"
     gene            14831..15301
                     /locus_tag="LSX49_001737"
     CDS             14831..15301
                     /locus_tag="LSX49_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007370547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL7168159.1"
                     /translation="MDITKILNTNRVILDMQATNKAEAIEELTNLLKKDGAIDCRETF
                     IKDVWQREAEGSTGFENHIAIPHGKSSAVINTTLAIGRTRQDIPWETLDGSSVRCIIL
                     FAVRLEDQNTTHIRLLSQVAGALADDDIIEQLLVETSPQKIIDLFSQYAQSDVC"
     gene            15319..15633
                     /locus_tag="LSX49_001738"
     CDS             15319..15633
                     /locus_tag="LSX49_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBL7168160.1"
                     /translation="MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGT
                     ENELQAADISAADVVILAVDVKIKGEERFTNKRIVRVKTEIVIKSPVQFLEKVEKSLG
                     NK"
     gene            15658..16749
                     /locus_tag="LSX49_001739"
     CDS             15658..16749
                     /locus_tag="LSX49_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBL7168161.1"
                     /translation="MKENKITVSQEIKKHLLTGISWMIPLIVAAGICIALGQVLGGTD
                     VGEKTGTIPWMLNQIGGWGMGLIVPLISAAIAYSIADRPGFAPGLIVGFLCGQIHTGF
                     IGGMLGGFLVGYTILLLKRYIRLPQSMQGLMPIMVLPVLSTIIGGLLMMTLIGKPIAW
                     LQEALIHLLESMQGGSRFLMGAILGAMATFDFGGPVNKTMSLFSDGLLVSGVYGPEAV
                     KFVGSIIPPFGITLSFLLTRHKYTRAEREALKAAFPMGICMITEGVIPIAARDLLRVV
                     GSCVVASAVAGGLIMVWGVESPVPHGGMFVVPLFTHPLLFCLALGIGTVICGVMLSLW
                     KKPVTERDEEFDELSDQKLKDEEITFTLE"
     gene            16761..17612
                     /locus_tag="LSX49_001740"
     CDS             16761..17612
                     /locus_tag="LSX49_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBL7168162.1"
                     /translation="MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPI
                     ILNLYQGHLAHFPAPVAAAVVKTLAESASVPVALALDHGKNPDCIRQAFRAGFSGLMI
                     DASAFPLEENVRQTRAVVELAASAQLCVEGELGHLADAPRYDQAANADLMTQPTDVEP
                     FIAQTGIDLLAVSVGTAHGMYAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQL
                     QLCTTLGVAKINVGAAIFERGKSALLHTLCHDISIELVDALKAMELAFEEAITPYLQA
                     SGAIGKA"
     gene            17693..18553
                     /locus_tag="LSX49_001741"
     CDS             17693..18553
                     /locus_tag="LSX49_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL7168163.1"
                     /translation="MLVSMKELLQPTRQHGFAIGAFNVADNCFLRAVVDEAEATNTPA
                     IIAIHPSEHDFVGDAFFAHVREITQRSPVPFVLHLDHGASVEHVLRAIRCGFTSVMID
                     GSLLPYEENVALTAEVVRLAHAVGVSVEGELGTIGQTGTSVEGGVSQVTYTDPAQAAD
                     FIARTGADTLAVAIGTAHGIYPKGMQPKLQMDILRDIAGRIDIPLVLHGGSANPDAEI
                     AESVTLGVGKINISSDMKYAYFQKVREILAKESWWDPNVIYPDAINAAREVIRHKMKL
                     FGSLGKASLY"
     gene            18601..19533
                     /locus_tag="LSX49_001742"
     CDS             18601..19533
                     /locus_tag="LSX49_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL7168164.1"
                     /translation="MHYLGLDIGGTKIAAVVMDAHGWEIRRYRCPTQKSTYQQFVSCV
                     VALIEQIRRDVQRPMLTGIALPGSISPLTGLIKNANIQVINGHALQADLQQLLGQPVV
                     IANDGNCFALSEACDGAGQDYDVVFGITLGTGCGGGIAIKQRPFIGAWGNAAECGHIT
                     LPGYTEQEDGPSVSCYCGKHNCVESFVSGSGFSERYQQMTGNLLTPAAIVTLAQRGDA
                     CAMQQVARFRQQLARTLATIVNVVDPGVIVIGGGLSNVELLITDLNAEVAPLVFTDQF
                     TTPIVKAQHGDSSGMRGAAWLAMRNGEANETFTN"
     gene            19514..20194
                     /locus_tag="LSX49_001743"
     CDS             19514..20194
                     /locus_tag="LSX49_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HBL7168165.1"
                     /translation="MKRSQINYVIDKAHAIAQTFRVCLPEFAYFTVDDWLQRERDNWQ
                     EVVDLQLGWDITDFGRGDFNQTGLTLLTMRNGALGSAAYPKPYAEKMLQIQQDQQTPW
                     HFHTHKMEDILNRGGGDLCMQLAWANEANLCDDQRVITVSVDGQRRTMKPGETLVLKP
                     GQGICLPPRLYHRFWAEKAFVLGWEISMVNDDQHDNYFLEPGGRFPAIEEDEPVKWLL
                     CGEYGILR"
     gene            complement(20238..21947)
                     /locus_tag="LSX49_001744"
     CDS             complement(20238..21947)
                     /locus_tag="LSX49_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HBL7168166.1"
                     /translation="MKFIGKLLLYILIALLVVIAGLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLKNVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPEAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRMADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVADLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFAPQGVALRQFTSRWEGG
                     MVRTSGNWQRDGKTLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNSLQLKRFSASRN
                     LIIDIDPDFPWQLTALDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQHWGWPEL
                     PLTGDGNIQLTASGDIQVNVPLKPTVSGQLHAVNAAKQQVTQTMNAGVVSSGEVTSTE
                     PVQ"
     gene            complement(22068..23459)
                     /gene="xanP"
                     /locus_tag="LSX49_001745"
     CDS             complement(22068..23459)
                     /gene="xanP"
                     /locus_tag="LSX49_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HBL7168167.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            23739..24944
                     /gene="gltS"
                     /locus_tag="LSX49_001746"
     CDS             23739..24944
                     /gene="gltS"
                     /locus_tag="LSX49_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HBL7168168.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLILKKSMGWEVNFDMSLRDPLMLAFFATIGLNANLASLRAGGRVVGVFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSMMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            complement(24978..27059)
                     /gene="recG"
                     /locus_tag="LSX49_001747"
     CDS             complement(24978..27059)
                     /gene="recG"
                     /locus_tag="LSX49_001747"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBL7168169.1"
                     /translation="MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFNAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARV
                     VAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIEVGWLAGKQKGKARLAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVRHACMTEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPAEKQAVMTSFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(27065..27754)
                     /gene="trmH"
                     /locus_tag="LSX49_001748"
     CDS             complement(27065..27754)
                     /gene="trmH"
                     /locus_tag="LSX49_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HBL7168170.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWSTMQAAG"
     gene            complement(27761..29869)
                     /gene="spoT"
                     /locus_tag="LSX49_001749"
     CDS             complement(27761..29869)
                     /gene="spoT"
                     /locus_tag="LSX49_001749"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HBL7168171.1"
                     /translation="MYLFESLNQLIQNYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            complement(29888..30163)
                     /gene="rpoZ"
                     /locus_tag="LSX49_001750"
     CDS             complement(29888..30163)
                     /gene="rpoZ"
                     /locus_tag="LSX49_001750"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL7168172.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            complement(30218..30841)
                     /gene="gmk"
                     /locus_tag="LSX49_001751"
     CDS             complement(30218..30841)
                     /gene="gmk"
                     /locus_tag="LSX49_001751"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBL7168173.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            31099..32781
                     /gene="ligB"
                     /locus_tag="LSX49_001752"
     CDS             31099..32781
                     /gene="ligB"
                     /locus_tag="LSX49_001752"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709426.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HBL7168174.1"
                     /translation="MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGNETRDVMIPPLNGAVMHPVAHTGVRK
                     MADKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVRL
                     ISAVPQTVSGPLANSTLQGEIFLKRKGHIQQQMGGINARAKVAGLMMRQGNSDTLNSL
                     AVFVWAWPDGPHLMTDRLKDLATAGFTLTQTYTRAVKNADEVAHVRNEWWKAKLPFVT
                     DGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLV
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHQFNLARQQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP"
     gene            complement(32778..33395)
                     /locus_tag="LSX49_001753"
     CDS             complement(32778..33395)
                     /locus_tag="LSX49_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HBL7168175.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(33647..34510)
                     /locus_tag="LSX49_001754"
     CDS             complement(33647..34510)
                     /locus_tag="LSX49_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBL7168176.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIIARETEGQALKVLIEQRL
                     EGVTAEVVKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            34637..35353
                     /gene="rph"
                     /locus_tag="LSX49_001755"
     CDS             34637..35353
                     /gene="rph"
                     /locus_tag="LSX49_001755"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBL7168177.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            35419..36060
                     /gene="pyrE"
                     /locus_tag="LSX49_001756"
     CDS             35419..36060
                     /gene="pyrE"
                     /locus_tag="LSX49_001756"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBL7168178.1"
                     /translation="MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV"
     gene            complement(36097..36693)
                     /gene="slmA"
                     /locus_tag="LSX49_001757"
     CDS             complement(36097..36693)
                     /gene="slmA"
                     /locus_tag="LSX49_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HBL7168179.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(36800..37258)
                     /gene="dut"
                     /locus_tag="LSX49_001758"
     CDS             complement(36800..37258)
                     /gene="dut"
                     /locus_tag="LSX49_001758"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBL7168180.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            complement(37236..38456)
                     /gene="coaBC"
                     /locus_tag="LSX49_001759"
     CDS             complement(37236..38456)
                     /gene="coaBC"
                     /locus_tag="LSX49_001759"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBL7168181.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVCVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVNRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            38628..39296
                     /gene="radC"
                     /locus_tag="LSX49_001760"
     CDS             38628..39296
                     /gene="radC"
                     /locus_tag="LSX49_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709417.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL7168182.1"
                     /translation="MKNNVQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            39513..39749
                     /gene="rpmB"
                     /locus_tag="LSX49_001761"
     CDS             39513..39749
                     /gene="rpmB"
                     /locus_tag="LSX49_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBL7168183.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            39770..39937
                     /gene="rpmG"
                     /locus_tag="LSX49_001762"
     CDS             39770..39937
                     /gene="rpmG"
                     /locus_tag="LSX49_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL7168184.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            40035..40844
                     /gene="mutM"
                     /locus_tag="LSX49_001763"
     CDS             40035..40844
                     /gene="mutM"
                     /locus_tag="LSX49_001763"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HBL7168185.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(40883..41362)
                     /gene="coaD"
                     /locus_tag="LSX49_001764"
     CDS             complement(40883..41362)
                     /gene="coaD"
                     /locus_tag="LSX49_001764"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBL7168186.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRASQMFDHVILAIAASPSKKP
                     MFTLEERVELAQQATAHLENVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(41370..42647)
                     /gene="waaA"
                     /locus_tag="LSX49_001765"
     CDS             complement(41370..42647)
                     /gene="waaA"
                     /locus_tag="LSX49_001765"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HBL7168187.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            43061..44119
                     /gene="rfaQ"
                     /locus_tag="LSX49_001766"
     CDS             43061..44119
                     /gene="rfaQ"
                     /locus_tag="LSX49_001766"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HBL7168188.1"
                     /translation="MDKPFRRILLIKMRFHGDMLLTTPVISSLKKNYPDAKIDVLLYQ
                     DTIPILSENPEINALYGIKNKKAKASEKIANFFHLIKVLRANKYDLIVNLTDQWMVAI
                     LVRLLNARVKISQDYHHRQSAFWRNSFTHLVPLQGGNVVESNLSVLTPLGLESLVKQT
                     TMSYPPANWKRMRRELDHAGVGQNYVVIQPTARQIFKCWDNAKFSAVIDALHARGYEV
                     VLTSGPDKDDLACVNEIAQGCQTPPVTALAGKVTFPELGALIDHAQLFIGVDSAPAHI
                     AAAVNTPLISLFGATDHIFWRPWSNNMIQFWAGDYREMPTRDQRDRNEMYLSVIPAAD
                     VIAAVDKLLPSSTTGTSL"
     gene            44116..45240
                     /locus_tag="LSX49_001767"
     CDS             44116..45240
                     /locus_tag="LSX49_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL7168189.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIAQTVAARGHHVRVYTQSWEGE
                     CPDVFELIKVPVKSHTNHGRNAEYFAWVQKHLREHPVDRVVGFNKMPGLDVYYAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEQGKPTQLLMLTDKQIADFQKHYQTEAE
                     RFHILPPGIYPDRKYSQQPANSREIFRKKNGITEQQYLLLQVGSDFTRKGVDRSIEAL
                     ASLPDSLRHNTLLYVVGQDKPRKFEALAEKRGVRSNVHFFSGRNDVSELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAIAEPFRQETLNEILRKA
                     LTQSSLRQAWAENARHYADTQDLYSLPEKAADIITGGLDG"
     gene            45233..46030
                     /gene="rfaP"
                     /locus_tag="LSX49_001768"
     CDS             45233..46030
                     /gene="rfaP"
                     /locus_tag="LSX49_001768"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312532.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HBL7168190.1"
                     /translation="MVELKEPFATLWRGKDPFEEVKTLQGEVFRELETRRTLRFEMAG
                     KSYFLKWHRGTTLKEIIKNLLSLRMPVLGADREWNAIHRLRDVGVDTMYGVAFGEKGI
                     NPLTRTSFIITEDLTPTISLEDYCADWATNPPDVRVKRMLIKRVATMVRDMHAAGINH
                     RDCYICHFLLHLPFSGKEEELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFGMPLRKILSFERNLLNMASVKAEHIKERTQRKGL"
     gene            46067..>46189
                     /locus_tag="LSX49_001769"
     CDS             46067..>46189
                     /locus_tag="LSX49_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HBL7168191.1"
                     /translation="MTIYFINWVADYELKMIQYLKKKHKIKNITTPKKYNWVNKK"
BASE COUNT        11155 a        11029 c        12119 g        11886 t
ORIGIN      
        1 attattcata tttttctcat tttgatttta tcaatttgat tattatttat cataaagaaa
       61 cgtcgcgaga ttattaaaga atatccatta atgtgcaatt gaaatgtgat aattatcact
      121 gaaccgttgt tgtcatttgt tttacaaaag caagggatta aatctcctcc aatggacaaa
      181 aaaatgaata atgacaatac cgattacgtg agtaatgaat cagggacgct ttcgcgatta
      241 tttaaactac ctcagcatgg gaccaccgtc cgcacagaat tgattgcggg gatgaccact
      301 tttttaacca tggtgtacat cgtttttgtg aacccgcaaa tcctcggcgc ggcacaaatg
      361 gacccaaaag tggtgtttgt taccacctgt ttgattgccg gtatcggcag tattgcgatg
      421 ggggtatttg ctaacttacc cgtggcactg gctccggcaa tgggcctgaa cgccttcttt
      481 gccttcgtgg tcgtgggggc gatgggtatc tcctggcaga ccgggatggg cgcgatattc
      541 tggggcgcag ttgggctatt tttgctcacg ctgtttcgta tccggtactg gatgatctcc
      601 aacattccat taagtttacg tattggtatc accagcggaa tcggattatt tatcgcctta
      661 atgggattaa aaaatactgg cgttattgtc gccaataaag acaccctggt gatgattggc
      721 gatttaagtt ctcacggcgt gttgttaggt attttagggt tttttattat aactgtgttg
      781 tcatcacgtc attttcatgc cgcggtgctt gtttctattg tggtgacgtc ttgctgtgga
      841 ttatttttcg gtgatgttca ttttagcggt gtctattcca ttccgcctga tattagcggc
      901 gtcattggtg aagtggattt gagcggtgcg ttatcacttg aactcgccgg tatcattttc
      961 tcctttatgc tgatcaactt atttgattca tcagggacat taattggtgt gactgataaa
     1021 gctggcttaa tagatagtaa cggtaaattc cccaatatga ataaggcgct gtatgttgat
     1081 agcatcagtt cggtggcggg tgcgtttatc ggtacctcgt ctgttaccgc ctatattgaa
     1141 agtacttcag gtgtggctgt cggtggtcgc acggggctga ctgcggttgt tgtcggcgtt
     1201 atgtttctgc tggttatgtt cttctcaccg ctggtggcga tggttcctcc ttacgcaacc
     1261 gccggagcgt taatctttgt tggcgtattg atgacatcga gcctggcacg cgttaactgg
     1321 gatgatttta ccgaatcggt gcctgcgttt attaccacgg tgatgatgcc ctttacgttc
     1381 tcgatcaccg aagggattgc actaggcttt atgtcgtact gcatcatgaa agtgtgcacc
     1441 gggcgctggc gcgatctgaa cctgtgtgtg gtggtggtcg cagctctgtt tgcactgaag
     1501 attattctgg tggattagta actggcgagg gtttccagat atcatgagtt ctgattacgc
     1561 aggagaactc atgatctgga taatgctcgc cacgctggcg gtagtgtttg tggttggttt
     1621 tcgggtgctg acatccgggg ccagaaaagc gattcgccgt ctcagcgatc ggctgaacat
     1681 cgatgtcgta cccgtggagt cgatggtcga tcaaatggga aagtcagccg gtgacgaatt
     1741 tttacgttat ttgcatcgcc cggatgagtc gcacctgcaa aacgccgcgc aggtgttgct
     1801 catctggcaa attgtcattg tcgatggtag cgaacagaac ctgctgcaat ggcatcggat
     1861 tttacaaaaa gcccgccttg ccgcgccgat taccgatgct caggtcagac tggcgctggg
     1921 ttttctgcgc gaaaccgaac ctgaaatgca ggatatcaat gcttttcaga tgcgctataa
     1981 cgcgttcttt cagcctgccg agggcgttca ctggctgcat taaaaccgct tcgtcttatc
     2041 agcctacaga ccgcgcctga cctggtgggt ggataaggcg tgtacgtcgc atccggtatc
     2101 ggaattgaca gtaggtgaac gcattatcta cgttctattt acagcagcac ctccagcccg
     2161 tgtttttgca caatgctgag cagttttaat gaaatgccat tggggcgttt agcgccactt
     2221 tcccattttt gtacagttga aacgctggta ttgagatagt gagcgaagac gggctgactc
     2281 acttttaatt tttcccgcag tgcttttatc tcaacaggtt gtaagtcttg cacgctggtc
     2341 aggcaggctt tgtcaaaagt acgcatcgtt tcggcagaaa tagcatcgac tctggacaat
     2401 ccagccgctg cgctgtgaat agcttcaaat gcaggacttt taaatttagt ttttgcagtc
     2461 atagcagatc tctgtcagtt ctttagtgtt aatcattgct gtcagttggg ctttcgtcag
     2521 gaaggcataa tgctttgcaa gttcacgaaa cccagccagt tcctgactat taatgttcga
     2581 catatcctgt tttgcatata aaaacgtgta aaaccaattg cttccccctt tcgccagaat
     2641 aattgcacgc tcacgatttc ggtgaaggcg ctttttaaaa acgccaccac caagtacatc
     2701 agctttacct tgttccgttt ctaaaatggc ccggcacaac tcttcatctg ttattgcatg
     2761 agacctggct tcccttgcaa accatttggt tttaaacacg cgcatatcgt tgagatcctg
     2821 ttattaaagt atatcaccaa gtgcaatact ttatccctta ttcccaacct aatcgcgaaa
     2881 atgcatatca ccttgcccta tgatttttat ttcttcgagc agcctcgaac ttttcccaca
     2941 acaccgtaaa agttgcaaaa acgttaaata cgtcacacat ttcaatgtta aagtggtcgg
     3001 ctttccctct gaaacatgcc acgggtaaca ccatgagtga atttattgct gaaaaccgcg
     3061 gcgcggatgc catcacccga ccgaactggt cagccgtttt ctcggtggca ttttgcgttg
     3121 cctgtcttat tatcgttgag tttttgcccg tcagtttgtt gacgccaatg gcccaggatt
     3181 taggcatttc ggaaggggtt gccgggcaat cggtgaccgt aaccgctttt gtggcgatgt
     3241 ttgccagttt gtttattacc cagaccattc aggccactga ccgccgctac gttgtcattc
     3301 tgttcgccgt tttgctgacg ctttcctgtt tgctggtttc ctttgccaac tcattcagtc
     3361 tgttgttaat cggtcgcgcc tgtctggggc tggcgctggg cggattctgg gcgatgtcgg
     3421 cgtcgctgac catgcgtctg gtaccgccgc gtacggtgcc gaaggcgctg tcggtgatct
     3481 tcggcgcggt ttctattgcg ctggtgattg ccgcgccgtt gggcagtttt ttaggcgagc
     3541 ttatcggttg gcgcaatgtc tttaatgcgg cggcggtgat gggcgtgctg tgtattttct
     3601 ggattatcaa atcactgcct tcgctgccag gcgaaccttc gcatcagaaa caaaatactt
     3661 tccgcttatt acaacgtccg ggagtgatgg ccgggatgat cgccatcttt atgtcctttg
     3721 ccggacagtt tgcttttttc acttatattc gcccagtgta tatgaatctg gcgggattcg
     3781 gtgttgatgg cttaaccctg gtgctgctga gttttggtat cgccagcttt gtcgggacat
     3841 cgctttcgtc gtttattctc aaacgttcgg tgaaactggc cttagcgggc gcaccgtttg
     3901 tgctcgccct gagcgcgctg gtactgacgc tgtggggaag cgataaaatt gttgctactg
     3961 gtgtggcgat tatctggggg ctgacctttg ctttaattcc cgttggctgg tcaacgtgga
     4021 tcactcgctc actggccgat caggcagaaa aagccggatc tattcaggtg gccgttattc
     4081 agcttgccaa tacctgcggt gcggcaatcg gcggttatgc gttggataac attggtctga
     4141 cttcgccgct gatgttgtcc ggcacattga tgttgctgac tgcattgttg gtgactgcaa
     4201 aggtgaaaat gaagaaatcc tgatatcagg taaagaagcg ttggtcagtg gttgttgccg
     4261 ttcttacata tccgggcatt ctaccttacc caacgcttcc caataattgc tctgattatt
     4321 acgttccatc gctacgatgg cttcgcgtat gtgttgttta ttgctttcat cagacaacat
     4381 taacttttcc cacgcttcat ctgataacga tgcctgcggg gtacaaattt tacgtaaatc
     4441 ttgcaatacc gtggttttct cttttgccga ctgtagggaa ctgaatggcg actcggcctg
     4501 agaaatggct ggaaaaatca ggaatatggt aatcatgagt agcatcgttg gcttcatagc
     4561 ggcaaccttc tgcaaatgtg catcgaatga agcataagtg tagtttgctt ttgccgctct
     4621 catcatgctg tacgaaaggt gtttgcgtgg tcagtaagaa gtgccagact ttatattcca
     4681 cttttattcc tttttattct tatcgatagc gtttcgtttt ttaaactgca gcgaccttac
     4741 cgctatagtc aggtaatcat taataaaagg ataaaaaaat gaaactgaca acacatcatc
     4801 tacgggcggg ggccgcatta ttactggcag gagttctgct ggcaggttgc gaccagagca
     4861 gtagcgatga aaagcatatt aaagttggcg ttattaatgg cgcagaacaa gatgtcgcgg
     4921 aagtcgctaa aaaggtagca aaagagaaat atggcctcga tgttgaactg gtaggattta
     4981 gcggttcgtt gctaccgaac gatgcgacaa atcatggcga gcttgatgcg aacgtcttcc
     5041 agcatcgacc ctttcttgaa caagataatc aggcgcatgg ttataaactg gtagcggtgg
     5101 gaaatacgtt tgtcttcccc atggcgggtt attccaaaaa aatcaaaacc gtggcgcaaa
     5161 taaaagaagg cgcgacagtg gcgatcccca acgacccgac taaccttggt cgtgcgcttt
     5221 tactgctgca aaaagagaag ctaattactc tgaaagaggg aaaagggtta ttacctaccg
     5281 cgttggatat aaccgataat ccacgccatt tgcagataat ggagctggaa ggggcacagt
     5341 tgccacgtgt actggacgac ccgaaagtgg atgtagcgat tatcagcacc acttacatcc
     5401 agcaaacagg actttctccg gttaacgaca gcgtatttat tgaagataaa aattcgccgt
     5461 atgtgaatat tctggtggca cgggaagata ataagaatgc agaaaacgtg aaggaatttc
     5521 tgcaatctta tcaatcaccc gaagtcgcta aagcggcaga aaccatcttt aacggaggcg
     5581 cggtgcctgg ctggtaattc tcactcatgc cgcgccggac gatttatttt tctggcgcgg
     5641 cggcgggaat ccattgaaat caaaatcacc gatgacagaa tcagcagcgt tcccagccag
     5701 tccggcaatg tgaaggtgat ccccagcaac agcaaagaga gcagtgcgct acttaatggt
     5761 tctgcacagc ttaaaatgct ggcttttgga ccaccaatta attgtgctcc tttcaggtac
     5821 agactaaatg tcagggacgt accaatgacc accaaataaa aaaacgccag aatcaaactg
     5881 ccgttaacga caaagtttgt cccttgtctg gcataaaagg gcagcaggat cagaccgcca
     5941 atgagcatac tccagccgac gaccggtaac gtgccatagc gagcaatcag cgttgaggga
     6001 taggtggtat agaatgcagc agcaaatgcc gaggcaatgc cccagaataa cgcggcagga
     6061 gagatcgata atgacgtcgg attaccgtgt gtcaccaata aaaaagtccc gatcagcgat
     6121 gtcaaaatag cgcaaaaaac caggatgccg gggcgggatt tacgcaccag tgagaaccag
     6181 gcgacgataa tagtcggtga gaggaattgc agcaccgttg ccgtggctgc gttcgatttt
     6241 tcgatggtta gcaaaaaagt gagctgtacg gttagcgcgc caaccacgga aaaaatcagt
     6301 aggctaatgg catctttgtg attgttaata atagaaaaga ttttatcacc atgaacaaat
     6361 gatagcgtca gcagaatcaa tccggcgaat atcaaacgcg tcatagtcaa aaactgcgac
     6421 gacatctggc tttgctccat gatgtattgc gcgcagaccc ctgaacttcc ccacaacacg
     6481 gcggcaatca gaacgttcag catccccttt ctggtggaac ccatttttcc ctctgcatac
     6541 tgttttgtct tttcatcaat atacgttaag gataccacta ccgatgacgg tgagggagta
     6601 gagtaatcaa tcagttttag tgaatggagg aaataatgac atataacaat tattcatatg
     6661 gtgtttaaaa aacctcacta aaaactcaat atgaaattta attatttaat gttcaataac
     6721 tctatggctt tagtatattc atcaggaata ccaattataa aacaaggtgc ggtatcggta
     6781 ggtagatttt ctttgttatc atcatccaga acagaaatag aaaactgtcg ttcaggtgtt
     6841 gatgttgtgg ttattaaaat ggttggatta ggaagagaaa catatgttgt ctcatttttt
     6901 agttttattc ctttgatgtt ttctttgtta attttatcaa tcgtttcaat agagaaaaaa
     6961 gaatcatgcc ccattcgcag ttcaatttta ttatcgtttt cgaataaata aagggcatta
     7021 ttgttttgaa acagattgaa tatattgtta gcgcaagttt gagttgctag ccaggatgcc
     7081 gctggatgac tcaaattaat atgtgtgcta aagactttga cgcgactact tctgtttttc
     7141 tctttacttt caattaaatg cctagcgctg ttggctgctt tacaagttcc atgccccaca
     7201 cggcaaaaat aatctcctga aaggatactt acaatcagta ttacaccaat gacgacagaa
     7261 aaaatagttc cgatgagttt gatgatgaca atccttgtgc agtgttattt tcaccatgga
     7321 ttataatgtt atagtgaaat tattgcacct gtaatttttc tttgattgtt ttaatcatca
     7381 catttacgca cttcttcatc tttgtagcag gtaaaagcca tatatggatg gctggtgtcc
     7441 ggtgcagata aaatgcaact tattcttgat agcttgaaaa aagagaggtt tttttgagtg
     7501 acggttgatg gtcggtggca aggaagacgt tttcgtacac tcggcaagaa aaatgaatca
     7561 ctctgtcata ctaccagata catcagcagg gtcaggttgc tcagaaataa gcaggatggg
     7621 gatcactgaa gaggcatttt ggcgatcaca ggagtcgcat ttgatggtta agttattgat
     7681 ttaatgttta tattttgaac ttgataaatg agtaacccca taagtacccc caaatggttt
     7741 tgcgtatggc gtttgggggg attccgggct actttttcga ctctttattc cactgtagca
     7801 aaccagcgat atccttctcg ccttcggctt cttttaagcg ccgttgttgt tcggcaaact
     7861 gaacatactc cgcctgcgct ttttcatcgg ccattttctt gctgatttta ccagcgccct
     7921 gtagaacctc tcggtcgtta aattgcagga actgatccag cttatcctgc cagtcgcgca
     7981 aaaagacttg ctgacgacga cgggcctgat cctcggcaaa gtccagccac atattaacca
     8041 cgcgattaag ttcgctgacc tcatcctggg tgagataatt ttttgccacc gtcacgtcgc
     8101 ccttacgtac ctcttcacct ttataactgg tcaagcccat gtgcggctgg ctggcatctg
     8161 ctcgtttgtg gatgagttcc gcagcggtat gcccggtaca ggcaaaatgc agtttattct
     8221 ggatggtttg aaaaaattgc gtggtttctt taagcgatgg ctgatagtcg gcagctaaag
     8281 caaagatctc ccgcacccgc aaatataccc gacgctcgct ggcgcgaata tcgcggatgc
     8341 gttcaagcat ctcatcaaaa tagtcgggca caaccgatga accgacaggc ggattcttca
     8401 gccgctcatc gtccatcaca aaacctttga tcaggtattc ctgaagcgtc tgggtggccc
     8461 actggcggaa ttgcgtgcct cgaggcgagc gaacgcgata gccgacagcg agaatggctt
     8521 cgaggttgta atggtctatc tctctggaaa cctgacgttt tccttcctgg cgaactatcc
     8581 ggaatttccg gatggttgag ttttgaacaa gttcaccttc ggaaaatata ttgattaaat
     8641 gttcgttaat agtgcgaaca tctttatcgt acagttcagc cattgccgcc tgggataacc
     8701 agattgtgtc tgactcaaag cgacattcaa cacgcactct tccgtcaccg ctggcaaaca
     8761 taataaactc gcctgctggg ggctgggtta agtctttgtc tgacatgttg cctccgaagg
     8821 agtgttgttg acgtcgggag agttcaggag aggcattttg gcggaagatc acaggagtcg
     8881 aacctgcccg ggaccgctgg cggccccaac tggatttgaa gtccagccgc ctcaccggag
     8941 acgacgatct tccgcgcctc gattgctaca tggaggcggg gcgcattata gctacttcct
     9001 tgagtttcta catcccccag atcagttttt tccgcctaat acacgcagcg tattatcacg
     9061 aaagcattat agttcatata aaactcatat tttacaatga tatatgagcg aaattaacgc
     9121 taccacgatc acataaaaca agaatcataa attaataacc agatatcgga atattcgctc
     9181 tcgcagggat ggtttacaaa atgcgttatc ggtctcagca cccctatagc atcaaggaaa
     9241 agcagatgaa gagtgaagtg ttgtccgtta aagagaaaat tggttatggc atgggagacg
     9301 ccgccagcca cattattttc gataacgtaa tgttatatat gatgttcttt tataccgata
     9361 tttttggcat tcctgccgga tttgtcggaa ccatgttttt ggtcgctcgt gcactggatg
     9421 cgatttccga tccttgcatg ggattgttgg ccgatcgaac gcgctctcgc tggggtaaat
     9481 ttcggccgtg ggtactgttt ggtgcactgc cattcgggat cgtctgtgta ctagcctata
     9541 gcacgccaga tctcagtatg aacggaaaaa tgatttatgc agcaattact tacaccctac
     9601 ttaccttact ttataccatc gtcaatatcc cttactgcgc attgggtggt gtaatcacca
     9661 atgacccgac tcagcgtatc tcgctgcaat cctggcgttt tgtgctggcg accgcgggag
     9721 gcatgctctc tactgttctg atgatgccac tggttaattt aattggtggt gataataaac
     9781 cactcggttt ccagggcggt atcgcggtcc tttccgtggt ggcatttatg atgctggcat
     9841 tctgtttctt caccactaaa gaacgcgttg aagcaccacc tacaacgacg tctatgcggg
     9901 atgatttacg tgatatctgg caaaacgacc agtggcgtat tgtcggtttc ctgaccattt
     9961 tcaatatcct ggcggtgtgc gtacgtggtg gggcgatgat gtattacgtc acatggattt
    10021 tgggtacgcc ggaagtattt gttgcttttc tcaccactta ttgcgtgggt aacctgattg
    10081 gttccgcact ggcaaaaccg ctgaccgact ggaaatgtaa agtcactatc ttctggtgga
    10141 cgaacgccct gctggcagtg attagcctcg cgatgttctt tgttcctatg caggccagca
    10201 tcaccatgtt tgtcttcatc ttcgtgattg gtgtgttgca tcaactggtg acacctatcc
    10261 agtgggtaat gatgtccgat accgtcgact acggcgagtg gtgtaatggt aaacgcctga
    10321 ccgggatcag ttttgctggc acgctgtttg tgctcaaact ggggttggcc ttcggtggtg
    10381 cccttatcgg ctggatgctg gcttatggcg gatatgatgc ggcagaaaaa gcgcagaaca
    10441 gcgccacaat tagcatcatt atcgcgctat tcacgattgt tccggcgatc tgttacttgc
    10501 tgagcgcgat tatcgctaaa cgctactact cgctcacgac gcacaatctg aaaaccgtta
    10561 tggaacagct ggcgcagggc aaacgccgtt gccagcaaca attcacctct caagaagtgc
    10621 agaactaagg aacggcaatg aaaattagcg acggaaactg gttgattcaa cctggcctca
    10681 atttgattca cccgcttcag gtgttcgagg ttgaacagca gggtaatgaa atggtggtct
    10741 atgctgcccc tcgtgatgtg cgtgaacgta cctggcagct tgatacgcct ttatttacgc
    10801 tgcgcttttt ctccccacag gaaggtattg tcggtgtacg gattgagcat tttcaggggg
    10861 cgctgaataa cggtcctcat tacccgctca atattttgca ggacgtgaag gtcactatcg
    10921 aaaacacaga acgttacgct gagtttaaaa gtggcaactt aagtgcgcgt gtcagcaaag
    10981 gtgagttctg gtcactggat tttctgcgca acggcgaacg tattaccggt agtcaggtga
    11041 aaaataatgg ctacgtgcag gacacgaata atcaacgaaa ttatatgttt gaacggctgg
    11101 atcttggcgt tggcgaaaca gtttacggcc tgggagagcg ctttactgcc ctggtgcgca
    11161 atggtcagac ggtagaaacc tggaaccggg acggcggcac aagtactgaa caggcgtata
    11221 aaaatatccc gttttatgtg actaaccgtg gttatggggt actggtcaat catccccaat
    11281 gtgtctcttt tgaagtggga tcggagaaag tctccaaagt acagttcagc gttgagagtg
    11341 aatatctcga atactttgtt atcgacggcc cgacgcctaa agcggtactt gatcgttata
    11401 cccgttttac tggccgtccg gcgctgccgc ccgcgtggtc cttcggtctg tggctaacca
    11461 cttcatttac caccaactac gacgaagcga cggtaaacag ctttatcgat ggtatggcgg
    11521 aacgcaatct gccgctgcat gttttccact ttgactgttt ctggatgaaa gccttccagt
    11581 ggtgcgattt tgagtgggat ccgctgactt ttccggaccc ggaagggatg atccgccgcc
    11641 tgaaagcgaa agggctgaaa atctgcgtct ggattaaccc ctatattggg caaaaatccc
    11701 ccgtctttaa agagttacaa gagaaaggtt atttactcaa acgcccggac ggttcgctgt
    11761 ggcagtggga taaatggcag ccaggtctgg cgatttatga ctttaccaat ccggatgcct
    11821 gcaaatggta cgccgacaaa ctgaaaggtc tggtcgcgat gggcgttgat tgctttaaga
    11881 ccgactttgg cgaacgtatt ccaaccgatg ttcaatggtt tgatggttcc gatccgcaga
    11941 aaatgcataa ccattatgca tacatctaca acgaactggt gtggaacgtg ctcaaggaca
    12001 ccgttggtga ggaagaagcc gtcttgtttg cccgctcggc ctccgttggt gcgcagaaat
    12061 ttccggtaca ctggggtggc gactgttacg ctaactacga atcaatggcg gaaagcctgc
    12121 gcggtggttt gtctattggc ctttcaggtt ttggcttctg gagccacgat atcggcggct
    12181 ttgaaaatac cgctccggcg cacgtttaca aacgctggtg cgcgtttggt ttgctctcca
    12241 gccatagccg tttacatggc agcaaatctt atcgtgtgcc gtgggcctac gatgatgagt
    12301 cctgtgatgt ggtgcgcttc ttcacgcaac tgaaatgccg catgatgccg tatctgtatc
    12361 gtgaagctgc acgtgcaaac gcccggggta cgccgatgat gcgggccatg atgatggagt
    12421 tcccggacga tccggcttgt gattaccttg accgtcaata catgttaggc gacaacgtga
    12481 tggttgcgcc tgtgttcact gaagcgggcg atgtgcagtt ctacctgccg gaaggtcgct
    12541 ggacacacct gtggcacaac gatgaactcg acggtagtcg ctggcataaa cagcagcaca
    12601 gcttcctgag tctgcccgtt tatgtgcgtg atagcaccct actggcgctg ggcaacaacg
    12661 atcaacgtcc cgattacgcg tggcacgaag gtacggcatt ccacctcttt aatctgcaag
    12721 acgggcatga agccgtctgt gaagtgccca ctgctgacgg ttcggtgatc tttactttaa
    12781 aagcagcacg tactggcaac acgattactg tgactggtac gggcgaggcg aagaactgga
    12841 cactgtgctt gcgcaatatt gtgaaagtaa atggtctgca aggcggttcg caggctgaaa
    12901 gtgagcaggg actggtggtg actcctcaag ggaatgcgct gacaattacg ttgtaatcta
    12961 ttgaagaatg ccggatacga atggttttgt gtcgtatccg gtaaataatc tcacatctgg
    13021 taataaatat ttcttccatc gtatttgcga gcatgatcac gattattcat cacgaaaatg
    13081 tgatctgtgc tgaaaaatat cccttaaccg ccttgctttg ttttatcact gtccggatta
    13141 cggacagatt ttagtattgt tgtgaaatta ttctgcttta tatttaccct cagagatggc
    13201 aactgaagct cttccatatg gggcttctta atctgtgata agggtaaaaa atgcaaatga
    13261 ttacctcgcg acaaaacaga ttattacgat tccttttacc tcgaagggaa tatacgacta
    13321 ttgttacgat tgccggctat ttaaatgttt cggaaaaaac cattcaacgt gatttacgtt
    13381 tacttgagca atggctggga caatggagaa taaatgttga gaagcgtgct ggcgcgggtg
    13441 tgatgttaag cgcggagaat attgctgatt tgctgcatct tgatcatttg ttggtggcag
    13501 aatgtgaaga gattgatggt gtaatgaata atgccaggcg cgttaaaata gcgtcgcagt
    13561 tattaagtga aacaccgaat gaaacgtcga tcagtaaatt gtcagaacgc tattttatca
    13621 gcggagcctc tattgttaat gacctgagag taattgagtc ctggcttgcg ccgttggggt
    13681 tatcgttgat ccgcagccca agtggtacgc atattgaagg tagtgaaggg caagtccgac
    13741 aggcaatggc attactgatt aacggcatta ttaaccataa tgagccgcaa ggtgtcgtgt
    13801 attcacgtct ggatcccgga agctataaag cattagtcca ttattttgga gaggaagaag
    13861 tgttatttgt ccagtcattg ttactggata tagaaaatga attaagttgg tctttgggag
    13921 aaccttatta cgttaacatt tttactcata tccttattat gatgtatcgc aacacgcacg
    13981 ggaatgcgtt atcaagagaa gaagatcaaa ccaggcaata tgatgaaaat atctttaatg
    14041 ttgccagtca gatgattcat aagatagaac aacgaattgc acatacattg cccgatgatg
    14101 aagtctggtt tatttatcaa tatatcattt catcaggtgt ggcgattgat ggacaaaaag
    14161 atgttagcat tatttcacat atgcaggcca gcaatgaagc gcgtctgatt acctggcgtt
    14221 taattacggt attcagtgac atcgtggact gcgattttag tgaagacagc gcattatatg
    14281 atggcttatt ggtgcatatt aaaccgctga ttaaccgact aaattatcgt attcatatcc
    14341 gtaatccatt gctggaagat attaaagcag aattagcgga tgtctggcgg ttgacgcaat
    14401 atgtggtgaa tcaggtattt aaaacctggg gtgagaatgc ggtgagcgag gatgaagtgg
    14461 attacctgac cgttcatttt caggctgcga tggaacggca aattgcccgt aaacgcgtat
    14521 tactggtctg ttcaaccgga atcggaactt cgcatctact gaaaagccgt attctgcgag
    14581 catttcctga atggacgatt gttgatgtta tttcagcagc gaatttatca caggttttgc
    14641 ctgacaatat cgaactgatt atttcgacca ttaatttgcc tacagtcact atgccggtcg
    14701 cttatgttac cgcttttttt aatgatgccg atattaagcg ggtcactgaa atggtgatta
    14761 cggaaaaatt acatcatgcg acgtctcggg tcgttgaaat ttaatgtcag aattttatga
    14821 ggtatgacga atggacataa caaaaatcct gaatacgaat cgcgttattt tagatatgca
    14881 agcgacgaat aaagcggagg cgattgaaga attaactaat cttctcaaaa aagatggtgc
    14941 gatcgattgt cgggaaacct ttattaaaga tgtctggcag cgcgaagcgg aaggctcgac
    15001 tggttttgaa aatcatattg cgatcccgca tggtaaatct tcagctgtga ttaatactac
    15061 gctggcaatt ggccgtaccc gccaggatat tccctgggaa acgctggatg gcagtagcgt
    15121 gcgctgtatt attttatttg cggtacgtct tgaagatcaa aataccaccc atatccgttt
    15181 actttcccag gtcgcgggcg cgctggcgga tgatgacatc atagaacaat tgttagttga
    15241 gacgagtccg caaaaaatca ttgatctctt tagtcagtat gcacaatccg atgtctgcta
    15301 aataacaggg agtatgtcat gaatattgtc tgtgttgccg cctgtacggc gggtattgct
    15361 catacctata ttgctcgtga aaagttaatc aaaggagcaa aagctctggg ccataccatt
    15421 aaagttgaaa cccagggaac cattggtaca gaaaatgaat tacaggcggc agatatctct
    15481 gctgctgacg tcgtgattct tgctgtagat gtgaaaataa aaggagaaga acgcttcacc
    15541 aataaacgta ttgtgcgagt aaagacagag atcgtcatta agtcgcccgt tcaatttctt
    15601 gaaaaggtcg aaaaatcact gggaaacaaa tgatccttat actggaggga tcttaatatg
    15661 aaagaaaata aaattacggt ttcacaggaa attaaaaaac atttattaac cggcatctcg
    15721 tggatgatac cccttattgt ggccgccggg atatgtattg cgttggggca agttcttggc
    15781 ggtacagatg ttggtgaaaa aacaggaaca atcccgtgga tgcttaatca gattggcggc
    15841 tggggaatgg ggctgattgt gccgctgatt agcgcggcaa ttgcctattc tattgccgat
    15901 cgtcccggat ttgccccggg cctgattgtc ggctttctct gtgggcaaat ccataccgga
    15961 tttattggcg gtatgttggg tggtttcctg gtgggctaca ccattttgct acttaaacgc
    16021 tatatccgcc tgccgcagtc gatgcaagga ctcatgccaa tcatggtgtt gccggtatta
    16081 agcaccatta tcggtgggct gttaatgatg acgctgattg gtaaacccat cgcctggtta
    16141 caagaagcac tgattcattt gctcgagtcg atgcagggcg gatcgcgctt cctgatgggg
    16201 gccatacttg gcgcgatggc aaccttcgat ttcggtggtc cggtcaacaa aaccatgtcg
    16261 ctgttttccg atggcttgct ggtcagtggc gtctacggac cagaagccgt gaaatttgtc
    16321 ggctcaatca tccctccgtt tggcatcaca ctttcgttct tactgacacg ccataaatac
    16381 acccgtgcgg agcgcgaggc gctgaaagcc gcgtttccga tggggatctg catgattact
    16441 gaaggagtca ttccgatcgc cgcgcgtgac ctactgcgag tagtgggatc ttgtgtggtg
    16501 gcatcggcgg tcgcgggcgg cttaatcatg gtgtggggcg tggagagtcc ggttccgcat
    16561 ggcggcatgt ttgttgtgcc tctgttcacc catcctctgc tgttttgcct ggcgctgggt
    16621 ataggcacgg tgatttgtgg cgtgatgctt tcactctgga agaaaccggt aacggaacgc
    16681 gacgaagagt ttgacgaact gagcgatcaa aagctgaaag atgaagagat cactttcacc
    16741 ctcgaataac cggaggccct atgtttgccg atatgaaaag tatggtgatg aaagcctggc
    16801 atgaacatta cgccttgctg gcgatcaact gtatgaatct ggaaagtgct cacgcagcta
    16861 tccgcgtggc ggagaagaat cgcgctccga tcattctcaa tctctatcag gggcatctgg
    16921 cgcattttcc tgcacccgtc gcggcggcag tggttaaaac gctcgcggaa tctgcctcag
    16981 taccggtcgc tctggcgctt gatcatggca aaaatccgga ctgtattcgt caggcgtttc
    17041 gtgctggttt cagcggatta atgattgatg cttctgcttt tcccctggag gaaaacgtgc
    17101 gccagaccag ggcggtggtg gaactcgccg ccagcgcgca gctctgcgtg gaaggcgaac
    17161 tgggccatct ggcagatgcg ccgcgttacg accaggccgc caatgcagac ctgatgacgc
    17221 aacccactga tgtggaaccg tttatcgcgc agacaggcat tgatctactg gccgtctcgg
    17281 taggcacggc gcacggcatg tacgcgcctg gcgttgtacc tgctattgat tttcagcgtc
    17341 tggcggagat tttccactgc tcgagcgtgc ctctggcatt acatggcggt agcggtacgc
    17401 cgttcgatca gctccagctc tgtacgactc tgggggtagc aaaaatcaac gtgggggcgg
    17461 ccatttttga acgggggaaa tccgcgctcc tgcataccct ctgtcacgat atatccattg
    17521 aactggtgga cgcgctgaaa gctatggaac tggccttcga agaagcgatt acaccgtatt
    17581 tacaggcgag cggcgctatc ggcaaagcct gattcatttt ctgtcatggc ctttatgcca
    17641 gtgcaataac gcaccggcag ggcggactac acgctgaaac tggagattta acatgttagt
    17701 ttcgatgaaa gaattactgc aacctacccg ccagcacggc tttgccattg gcgcatttaa
    17761 tgtggcggat aactgtttcc ttcgcgcagt cgtggatgaa gcagaagcga caaatactcc
    17821 ggcgattatt gccatccatc ccagcgaaca tgattttgtg ggcgatgcct ttttcgctca
    17881 cgttcgcgaa attacccagc gtagtccggt cccgtttgta ctgcacctcg atcatggtgc
    17941 ctctgtagag catgttttgc gtgcgattcg ctgcggattt acctcagtaa tgatcgacgg
    18001 ttcgctgctg ccgtatgaag aaaacgtggc gctgaccgca gaagtggttc gcctcgctca
    18061 cgcggttggc gtgtcggttg agggtgaact gggaaccatc ggacaaacag gaacgtcggt
    18121 agaaggtggt gtttcacaag tgacctacac agatccggcg caggccgccg attttattgc
    18181 tcgtacaggt gccgacacac tggctgtggc gattggtaca gcgcatggca tctatccaaa
    18241 agggatgcag ccgaagctgc aaatggacat tttgcgcgac attgccggac gtattgatat
    18301 tccgctggtg ctacacggtg gttcggcaaa cccggacgcg gagattgctg aatcagttac
    18361 gctcggcgtc ggcaaaatca atatctccag cgatatgaaa tacgcctatt tccagaaagt
    18421 gcgtgaaatt ctcgctaaag agagctggtg ggacccgaac gtcatctatc cggatgcgat
    18481 taacgcggcg cgggaagtca ttcgccacaa aatgaaactg ttcggttcgc tcggtaaagc
    18541 atcactgtac taagccagaa gggcggggtg acccgccttt tacgcaacaa ggaacgagat
    18601 atgcactatc tggggttgga tattggtggg accaaaatcg ccgccgttgt catggatgcg
    18661 catggctggg agattcgccg ttaccgctgc ccgacgcaaa agtcgacata tcaacaattt
    18721 gtctcatgcg ttgtggcgct tatcgagcag attaggcggg acgttcaacg accgatgctg
    18781 acagggatcg ccttacccgg cagtatctcg ccactcactg gcctgattaa aaacgcgaat
    18841 attcaggtga ttaacggtca tgcgttacag gctgatttgc agcaattgct tgggcaaccg
    18901 gtggtgatag ccaatgatgg taactgtttc gcgctatcag aagcttgcga cggtgccggg
    18961 caagattatg acgtggtatt tggtattacg cttggtacgg gctgcggcgg tggcattgcc
    19021 atcaagcaac gaccgtttat aggggcctgg ggaaatgctg ccgaatgcgg tcatatcacg
    19081 ttgccaggct atacggagca ggaagatggt ccatcagtca gttgctattg cggcaaacac
    19141 aactgcgtgg agtcgtttgt ttccggcagc ggttttagtg aacgctatca acagatgact
    19201 ggtaacttgc tcactcctgc ggcgattgtc accctggcac aacgtggtga tgcttgtgcc
    19261 atgcagcagg tggcacgttt tcgccaacag cttgcccgca cgctggcaac catcgttaac
    19321 gttgttgacc ctggcgtgat tgtgatcggc ggcgggcttt cgaatgtgga actgcttatc
    19381 accgatctga acgcagaagt cgctccactg gttttcaccg atcaattcac cactcccatt
    19441 gtaaaagcac agcacggcga cagtagcgga atgcgtggcg ctgcctggct tgctatgcgc
    19501 aacggagaag ccaatgaaac gttcacaaat taattatgtt attgataaag cacatgccat
    19561 tgcgcagacc ttccgcgttt gtttgccaga gttcgcctat tttacggtgg atgactggct
    19621 gcagcgggaa cgggataact ggcaagaagt ggtcgactta cagctcggtt gggatatcac
    19681 cgattttggt cgtggtgatt tcaaccaaac gggactaaca ctgctaacga tgcgcaacgg
    19741 cgcgctgggg tcggcggcat atccaaaacc gtatgctgag aaaatgttgc agatccaaca
    19801 agatcagcag actccctggc attttcacac ccacaaaatg gaagatatcc tcaatcgggg
    19861 cggtggagac ttatgcatgc agttggcctg ggccaacgaa gccaatctct gtgatgatca
    19921 acgagtcatt accgtgagtg ttgatggtca gcggcgtacc atgaaacctg gtgaaacgct
    19981 ggtgctaaag ccggggcagg gcatttgcct gccgccgcgt ctgtatcatc gcttctgggc
    20041 ggaaaaagcg tttgttctcg gctgggaaat ctcgatggta aatgatgacc aacacgataa
    20101 ttattttctt gagccgggag gacgttttcc ggcgatagaa gaagatgaac cggtgaaatg
    20161 gttattgtgc ggtgagtatg gaattttgcg ctaataacgg ggaacgctag cgctgatatc
    20221 cgctagcgtc cttattttta ctgcaccggc tccgtcgacg taacttcacc actggaaact
    20281 acgcccgcat tcatggtttg agtcacttgc tgctttgcgg cattcacggc atgcaattgc
    20341 ccgctaaccg taggtttcag cgggacattg acctgaatat cgccactggc ggtaagctga
    20401 atattgccgt cgccagtcaa cggtaattca ggccatcccc aatgttgcaa aatattcacc
    20461 ggcacaccgc gtccattcag gctgatatgg gtctgacgtt gtggcgtttg tgaaacactg
    20521 gcggtggctt ccagaatgcc tttttcagta aatgcactca gttcgctgat attcaccgtg
    20581 ctgctgttgg cagttagcgc cagcgacgga cgacggacat caacacgatt aaacgttgcg
    20641 gcggcggcat tcagattcgc cgagccactc cagacgcccc atttatgatc ggtaaccagc
    20701 gtcagattgg caccgtaacc atcgagcgcg gtgagctgcc acgggaagtc agggtcgata
    20761 tcaatgatca gattgcggct ggcgctaaat ctcttcagtt gcaggctgtt taaccaaccg
    20821 ggtgtcgttt ccatccacaa ctgttgccag tttttgggca aggtatattc cagtccggca
    20881 attgccgcat catcgaggat cagcgttttc ccgtcgcgtt gccagtttcc tgacgttctg
    20941 accatacccc cttcccagcg gctggtgaac tggcgcagtg ctacgccctg cggggcaaat
    21001 tccgcgttta taatcggatc aaataaatgc agcgagccat aaataaactc gctggcgttc
    21061 atcgacagtt taccttcctg tgtctgccag tcatctttac tgaaggtcat gttgcgcaag
    21121 ctgagatcga ggtcggccac cgcccagtcc ggaccttgca aacgagcgtc gatgacttcc
    21181 aggcgaccaa tctgcaacga cgggacagag cgtaatggtg caaagaagtc ggttagcgat
    21241 ttttcgcttt gtagacggat atccgccatg cgcaggtttt ccacttgcca gctgccgtca
    21301 gcgttacgct gcgcgtttcc ggttaatgtc ccgcgggcga tgtcggcacc caggttagtc
    21361 agcgtaacgc gatcgttatc aatactgcct tcaatcagta cattggtggc aggaacatca
    21421 ttgagcgaaa gcgatccggc actaaactga atctgtgcct tcgtacccag cactttaccg
    21481 gcttctggtg accacggaac cacgccgcca tttacccgct gcgcgctcag tttccattcg
    21541 ctattcgggc tattaaacgc catatcacgc agttgcagac gatcggcttt gaacggtagc
    21601 ggcgcggtct ggtcggtgag attcagcgtc ccgttttcca gcaggatggt atcgacatgg
    21661 cgtggttcgg tcagttgccg actgcttagc gcaatgtcga cactttttgc taccagggtc
    21721 gcgggctggc catcacggcc aaacgtgacg ttcttcagca cgatatgaga tggcgcggaa
    21781 aaacggtgat ccatcgcccc gaaggccaga tgatagtcgc tattctcgga aacccatgcg
    21841 ctgatatgtt ctgctcccca gcgagtttgc agaagaaaat agaggccagc gatcaccact
    21901 aacagagcga tgagaatgta gagaagcagc ttcccaataa atttcatggt cttccatccc
    21961 gtgaaatgca cataagggag ttatgcacga tttacgcgca atcctcaagg cgggaatggt
    22021 gaaagaggtg agactgcggc ggtaattatc ttaccgccgc cagtgaatta ctgtttttct
    22081 ggtgggaaaa tcagattcag cacgatggca gtaataccgc ccgcggcaat cccggaggag
    22141 agcaggtttt tcagccattc aggggcaaac tgcaaaatca gcggctgctg agacacgccc
    22201 agaccgaccg ccagcgacag cgcgataatc agaatcgccc ggcggttcag cggctcacga
    22261 gaaacgatac gcacaccgga ggcggcgatg gtgccaaaca ttacaagcgt tgcgccgccc
    22321 agaaccggtt ctggaatgtg ttgtacaaaa ccgctcactg ccgggaacag acccagcacg
    22381 atcaacatca gcgcgacgac aaaaccgaca tagcggctgg caacaccggt taactggatc
    22441 accccgttgt tctgcccgaa gcaggagttc gggaaggtat taaataccgc cgagacaaac
    22501 gagttcaggc cgtttgccag tacgccgcct ttcaggcgtt tcatgtacag cggaccggac
    22561 actggctgtt cggaaacgtc agaggtcgcc gtgatatcgc caatggtttc cagcgaagtg
    22621 atcataaaga ccagcatcag cggcagcagc agactccatt caatgccaag accgtaatag
    22681 agcggcgttg gcaccataat cagttcttgt gtcatcggtt cgttgctttc tggcaacatg
    22741 cccataaacc acgccagcgc atatccggcc gccatcgcaa tcaccagtga ggccacgcgt
    22801 aagtaagggt tacgttgacg gttaagcagg ataattaagg ctaagaccac gcctgccagc
    22861 agcagatttt tcggtgcgcc gaaggtgtta tcgctcatgg ctgcgtaacc gccgccaatg
    22921 gaggtcagtc caacctgaat tagcgacagg ccgataatca tcaccacaac gccagaaacc
    22981 agcggcgtaa taatgcggcg cgccagatgc agaacgcggg agatcaccat ctcggtacaa
    23041 cttgccagca tcaacgtgcc gaacaaagct gccatcatgg taggaacatc agcaccaccg
    23101 gtcttcagcg ctgtgccgcc cataatcagc ggagcaacaa agttgaagct ggtgccctga
    23161 atagacaaca acccggagcc aaccggaccc caggccttaa tttgaataat cgatgccaca
    23221 ccggaggcaa acagcgacat actaataatg tgttgcgtgt cttgtgccgg taaacccagc
    23281 gcctggcaga ttaatagcgc tggcgtgatc accgcaacga acatcgccag caaatgctga
    23341 caggcggcaa acagagtttg aggaagcggc ggacgatctt caagacggta aatcagttcg
    23401 ctgttttgag tctgcgcaac cggttgcgca ttttctgact cgagggtgga aacagacatc
    23461 gaaaacaatc ccgtggtagc aaagcgggca ttttagctga ccgaaagaga aaagcaaacg
    23521 tttgccacat cctcatctaa atatttaaat gagataaatg tactttttta tataactttt
    23581 agttgttttc tgcttaaaat ccatgccatt tttctatttt cagcgaagaa ttcgaaccag
    23641 gaaagcatga ctcgatactc gtcatatttc gccttactgc aaatgcgcga tgaagtatga
    23701 cgagtatgaa agagtgatgc ggacacaaag gagtaactat gtttcatctc gatactttag
    23761 caacgcttgt tgccgcaacg ctgacgttgc tgctcgggcg caagttggtc cattccgtct
    23821 cctttttgaa gaaatacacc ataccggaac ctgttgcggg tggtttatta gtggcgctgg
    23881 cgctgctgat actgaaaaaa agcatgggct gggaagtcaa ctttgatatg tccctgcgcg
    23941 atccgttgat gctggctttc ttcgccacca ttggcctgaa cgccaacctt gccagtctgc
    24001 gagctggtgg gcgtgtggtg ggggttttcc tgattgtggt tgttggcctg ttggtgatgc
    24061 aaaatgccat tggcattggt atggctagcc tgttagggct tgatccgctg atggggctgc
    24121 tggccggttc tattacgctt tccggcggtc acggtacggg tgctgcatgg agtaaattgt
    24181 tcattgaacg ttatggtttc accaacgcga cagaagtggc gatggcctgt gcaacgttcg
    24241 gtttggtgct gggcggcttg attggcggtc cggtggcgcg ctatctggtg aaacactcca
    24301 ccacaccgaa cggtattccg gatgaccagg aagttccgac ggcgttcgaa aagccggatg
    24361 tgggccgcat gatcacctcg ctggtgctga ttgaaactat cgcgctgatt gctatctgcc
    24421 tgacggtggg gaaaattgtt gcgcaacttt tggctggtac tgcttttgaa ctaccgacct
    24481 tcgtctgtgt actatttgtt ggcgtgattc tgagcaacgg tctgtcaatg atgggctttt
    24541 accgcgtctt tgagcgagcg gtatccgtgc tgggtaacgt aagcctgtcg ttgttcctgg
    24601 cgatggcgct gatggggctg aaactgtggg agctggcttc gctggcgttg ccgatgctgg
    24661 cgattctggt ggtacagacc atcttcatgg cgttgtacgc catcttcgtt acctggcgca
    24721 tgatgggcaa aaactacgat gcggcagtgc tggctgcggg tcactgtggt tttggcctcg
    24781 gtgcaacgcc aacggcaatc gccaacatgc aggcgatcac tgaacgcttt ggcccgtcgc
    24841 acatggcgtt cctggtcgtg ccgatggtcg gtgcgttctt tatcgatatc gtcaatgcgc
    24901 tggtgattaa gctgtatttg atgttgccga tttttgccgg ttaaccgatg aagcggcggt
    24961 cttctcaccg ccgcttttta cgcattcgag taacgttctg tttctggcat ccagcgttct
    25021 atcagggctt ttgcctgttg tgggtaacgt tcgtgaatat gtcgcgccag gcgctgaact
    25081 tccgggatca tcgcctgatc gcgcagtaaa tccgccactt taaattcagc attacccgtc
    25141 tgacgtgtac ctaacaattc gccagggccg cgaatctcca gatctttctg tgcaatcaca
    25201 aaaccatcgt tgctgtcgcg tagtacctgc aggcggattt gcgcggtttt ggagagcggc
    25261 gttttgtaga gcagcacgca gtgagaagcc accgcgccac gacctacacg cccgcgaagc
    25321 tggtgtaact gcgccagacc cagacgctcc gggttttcga taatcatcag actggcattg
    25381 ggtacatcaa caccgacttc aatgacagta gtggcaacca gcaggtgtag ctcgccttgt
    25441 ttaaacgatg tcatcaccgc ctgtttctcg gcgggtttca tccgtccgtg taccaggcca
    25501 acattcaact ctggtagcgc cagtttcaac tcttcccagg tcgcttccgc cgcctgcgct
    25561 tccagtaatt ccgactcttc aatcaacgta caaacccagt acgcctgacg cccttcagtc
    25621 atacaggcgt ggcgcacgcg gtcaatgatg tcggtacggc gggtatcagg aatagcgacc
    25681 gtagtcactg gcgtgcggcc tggtggcagc tcatctatca ccgaggtatc gagatcggca
    25741 tacgcagtca tcgccagcgt gcgggggatg ggcgtggcgg tcatgatcaa ctgatgcgga
    25801 tggaagccct gctgctggcc tttctcccat aacgccagac gctgatgcac gccaaaacga
    25861 tgctgttcgt cgataatcac cagcgccagg ccgttaaact gcacctgttc ctggaaaatg
    25921 gcgtgcgtac caacaatcat ctgcacctga ccgctggcga tggcttcttg ctgagccagt
    25981 cgtgctttac ctttctgttt tccggcgagc cagcctactt cgataccgag cggtgcaaac
    26041 cagttacgga agttattggc gtgctgctcg gcgagtaatt cggttggtgc catcaatgcc
    26101 acctgtttgc cgtgcgcaat cgcacgcaac gcggcgaggg cggcgaccag cgttttaccg
    26161 gaacctacat cgccctgcac cagacgcatc atcggcacat ccagcgccat atcgcgctcg
    26221 atctccgcca ctacgcgtgc ctgtgcgccc gttggcttga acggtaaggc ggcgaggagt
    26281 ttatttttca gcgcgtcatt ggcgctcagc ggctgagcat gaaaacgttg tgcaccggca
    26341 cgtaacgcca acatgctgag gttgtgcgcc agcaactctt ccagaatcag ccggcgttgt
    26401 gccggatgct gcccggtttc gagatcgcta agctgtagcg tcggcggtgg gcggtgcaaa
    26461 gtgcgcaacg cttccggtag cgtcatcatt ccttgtgaca gttccggcgg caggagttct
    26521 tcaatggcgc atgtgtcgag cagatccagc gcctggtcgg ttaatttacg cagcgtagcc
    26581 tgctttacgc cttccgtagt tgggtaaacc ggcgtgagcg tttcctgtaa ctctggcgtg
    26641 ctgagatcgc cctgtacgcg gtattccggg tggatcatct ccgcaccata tttgccgcgc
    26701 tttgcttcgc cataggccag cacgcggcgg cctgtcgcca ggctattttt cattgccgca
    26761 ttgaagttga aaaagcgcat agtgagaatg ccggaaccgt cgctgatctg gcaggtcatc
    26821 atccgccgac cgccgaagga gatattgcag ttcagcactt cgccttccac cgtggcataa
    26881 acacccggca gtagttcacc gatggggtag agatgtgtgc gatcttcgta gcgcagagga
    26941 aggtgtaaga gcaaatcctg tacggtatgc aggttgattt tcgccagctt gttactaagc
    27001 gctgcgccaa cgcccgttag ggaactgagc gggacagcat ctaacaggcg acctttcatc
    27061 gcgcttaccc tgcggcctgc atggtggacc accagtcagc atcggcttca atctcgcctt
    27121 gctgattaac gtgggggtag ggcagacctt tgcgttttgc gactttcgcc agcaccggat
    27181 agccgccttc aaacagcagg cgttgttgct cggcttccgg caacatgctg ttttcacgca
    27241 ggtacatgcc cgcattttgc cgctggcgct gggcttcgta aagaatgagg gctgaggcaa
    27301 cggaaacatt cagcgactgc accatgccga tcatcggaat gatgatatcc tgatccgcca
    27361 gggccaacgc ttcctgcgtg atgcccgttt tctcctgtcc catcaaaata caggtcgggc
    27421 gagtgtaatc aatttcgcgg aaatcaacag cgttatcaga aagatgggtt gccagaatct
    27481 gcatgccctg gcctttcaga tgagcgacgg catcgccaat ggtgcggtgc gttttcacct
    27541 gtacccagct gttactaccc gcagctgccg aagccatggt gcgcatccgg ctgccaggcc
    27601 agacagcatg aacttcatgt acgccaacgg catctgcggt acgaataatc gcagaaacgt
    27661 tatgaggttt gtggacctgc tccatgcaga cggtcagatc aggctgccgc ctggcgagca
    27721 tttcgcagat gcgtgcataa cgtgttgggt tcataaaaca ttaatttcgg tttcgggtga
    27781 ctttaatcac gtctggcatc acgcggattt tgcgcatgat attcgccaga tgcacacggt
    27841 cacgggcggt cagacgaata aaggcgctat agacgcgacc atctttctct tccgtattca
    27901 aactttgaat attcgaggtc gtggtgttaa ttgccgccgt caggtttgcc agcgcgccct
    27961 gatgattgaa catctccacc ttgatttcgg tgatgaattc ctgcgccgtc tctttatccc
    28021 attcaacagc cataaacttc tctggctctt tctggtagcc acggatgtta cggcaggatt
    28081 catggtggat caccagacct ttaccggggc tgacgtgggc gataatcggg tcgccaggaa
    28141 ttgggcggca gcatttcgca aaggtgatca gcacgccatc ggcaccttta atgggcagat
    28201 gtccgtgact ttgggttgcc ggtggaatgg aggcgtcccc atgttgcaga tttttcgcga
    28261 ccaccacgct cattgcgtta ccaaggccga tttctgccag cagatcgtca agcgttgcca
    28321 gcttcatgcg gtccagctcg cgctgaatat tttcctgcgg gatttcattg agcttacggc
    28381 taccacccaa cgcatggttg agcagacgac ggcccaggct tacagaatca tcacgcttga
    28441 ggtttttcag caactgacga attttggcgc gcgctttcga gctgacgaca aagttcagcc
    28501 acgcggcatt cgggcgagca cccggtgcgg taatgatttc aacggtttga ccgctagtaa
    28561 gcggctgcga cagcgggtaa ggctggcggt cgacgcgtgc gcccacgcag gcatggccga
    28621 tatcggtatg caccgcataa gcgaagtcga cgggcgttgc accggcaggc agttcgacaa
    28681 tgcgcccttc tggtgtgaaa acgtaaatct catccgggaa gagatcggat ttaacgctct
    28741 cgataaattc aaacgagcta ccggcactct gttgcagctc cagcaggctt tgcatccagc
    28801 gctgggcgcg tatttgcgcg gtagtgctgg tttcgccgtg ctctttataa gcccagtgcg
    28861 cggcaacacc catctccgcc atctgatcca tatcttcggt acggatctgg acctcaaccg
    28921 gcacgccgtg cgggccaatc atcgaggtgt gcaaagactg atagccgttc gcttttggaa
    28981 tggcgatata gtctttcacg cggcccggac gcggcttgta caggctgtgc atctggccca
    29041 gcacgcgata acaggtgtca gaatcattga cgatcacgcg gaaagcgtag atgtccatga
    29101 ttgagtgaaa acgctgctct ttgagcacca ttttgcagta aatcgaataa agatgctttt
    29161 cgcgaccact gacgcggcac ggtattcccg cttcctgcaa acgcccttcg atttcagaaa
    29221 gaatcttctg gatcatctct ttacggttgc cgcgcgcggc tttcaccact tctttgatta
    29281 cgcgataacg gttgggatac agcgcctcaa aacccagctc ctcgagttcg gttttaatgt
    29341 ggtggatacc taaacggtgc gccagcgggc tgtatatttc gagagtttca cgggcgatgc
    29401 ggcgacgttt gtccgggcga agtgagccca gcgtgcgcat gttgtgggta cggtcggcaa
    29461 gtttgatgag aatgacgcgg atatcctgca ccatcgccat aatcatcttg cgaaagtttt
    29521 cggcctgcgc ctctttctta tcgcggaact tgagtttatc aagtttcgac accccctcta
    29581 ccagctcggc gacgctttta ccaaaaagct gttccatgtc ctggtaggtg gcgggtgtat
    29641 cttcaatcac atcatgcagc agcgccgcca tcagcgtttc atagtcgagt ttcatctcgg
    29701 ccagaatgca ggcaaccgcc accggatgcg tgatataggg ttcaccgctt gaacgtgttt
    29761 gcccctcgtg agcatcacgt gcaacgagat acgcctgccg cagacgcttg atttggtctt
    29821 ccggcaggta gttttgaatc agctgattca ggctttcaaa cagatacaag ggcgacccgc
    29881 tttgtgatta acgacgacct tcagcaatag cggtaacggc ttgtaattca gcggcttcct
    29941 gctcttgctg ctcctggcgt tcgcgaacgt cgaggatctg gttgttgatc agaccttctt
    30001 cgatttcgcg cagcgcgatt acagtggttt tatcgttttc ttccggtacc agcggatcct
    30061 ttccgcctac ctgcatctga cgagcgcgac gcgcggcgac cagtaccagg tcaaaacggt
    30121 taccaatttt ctctacagcg tcctgaacag ttacgcgtgc catacttaaa aagctccaca
    30181 ggtgaagaaa tgactgggca tgatactgaa atcaggttca gtctgccaac aatttgctga
    30241 ttaaagcgtc atgacgctgc ttttggcggc tcatgcgcag acgttcggcg cgaataatgg
    30301 tcttcaaatc ggtcaacgcg gtatcgaagt catcattcac aatcaggtaa tcatattcgg
    30361 cgtaatggct catttctgca acagcttgcg ccatacgctt tgcaatgacc tcttcgctgt
    30421 cctgaccgcg accgcgtaga cggcggtcca gttcgatttt agacggcggt aaaataaaga
    30481 tactccgcgc gtgcggcatc ttctggcgaa tttgctgcgc accctgccag tcgatatcga
    30541 gaaaaacatc gacaccggtc gccagtactt gctcaatggc ctcacgcgaa gtgccatagt
    30601 aattaccaaa aacttctgcg tgttcgagga acgcatctct actaatcatt tctttaaatt
    30661 catcatgatt aacaaagaaa taatgttcac cgtggacttc accaggacgc ggttggcgtg
    30721 tggtgtgtga aacagaaacc tgggtgtcat acaacggttg ggtttttaat aaagcctgaa
    30781 tcaggctgga tttacccgcg ccactggggg cagaaacaat ataaagcgtg ccttgagcca
    30841 tgagtatctt tcgtatgtga ttagcgaaat aaagcctaca tacgagctta ttatacacgg
    30901 cgcggccatg tgacgtagcc cttgctcaca ctttttgcgc aaagttgttg cgttttgcgt
    30961 agctgcttcc gcatttgcct gtgattcact gcaataaaga cgattctcag gaagcgtcct
    31021 cgcagactcc gtttttgcca ctcggctttg ccttcaccac attgtatatc tgcctgacta
    31081 tctacagcgg aggtgatgat gaaagtatgg atggcgatat taataagtat cttgtgctgg
    31141 caatcatcgg tgtgggcggt ctgtccggcc tggtcgccag ccagagcaca ggaagaaatt
    31201 tcccgcctgc aacagcaaat aaaacagtgg gacgatgact actggaagga agggaaaagt
    31261 gaggtggaag acggtgttta cgatcagtta agcgcccgtc ttacgcagtg gcaacgctgt
    31321 tttgggaacg agacccgcga tgtgatgata ccgcctttaa acggtgcggt tatgcatccg
    31381 gttgcccata cgggtgtacg caaaatggcg gataaaaacg cattaagtct ttggatgcgc
    31441 gaacgtagcg atctttgggt gcagccaaaa gttgatggcg ttgcggtaac cctggtttat
    31501 cgggacggga aactgaacaa agcaatcagt cgcggcaatg gcctgaaagg cgaggactgg
    31561 acgcagaaag ttcgcttaat ttccgctgtg ccgcaaaccg ttagcgggcc tttagccaac
    31621 agcacgcttc agggggaaat atttctcaag cgtaaggggc atatccaaca acaaatgggg
    31681 ggaataaatg cccgcgcaaa agttgctggc ctgatgatgc gccaggggaa tagcgatacg
    31741 ctaaactcac tggctgtttt tgtctgggca tggccggatg gaccgcattt aatgaccgat
    31801 cgtttaaagg atctggctac cgcaggtttt actttaacgc agacgtatac ccgcgcggtt
    31861 aaaaatgctg atgaggttgc gcacgtacgc aatgagtggt ggaaagcaaa attacccttc
    31921 gtcaccgatg gcgtggttgt gcgagcggcg aaagaacccg aatcccgtca ttggctaccg
    31981 ggccaggcgg agtggctggt ggcctggaaa tatcaacctg tagctcaggt tgccgaagtg
    32041 aaggcgattc agtttgcggt gggtaagagc ggtaaaatat cggtggttgc gtcacttgta
    32101 cctgtcatgc tggatgataa aaaagtccag cgggtgaata ttggttccgt caggcgctgg
    32161 caggagtggg atattgcgcc tggtgatcag atcctcgtca gccttgccgg tcaggggatt
    32221 cctcgcattg atgatgtggt ctggcgcgga gcagaacgta caaaaccgac accaccagaa
    32281 aaccgcttta actcgttgac ctgctacttt gcttctgatg tttgtcagga acagttcatt
    32341 tcacgcttag tctggctggg gtcaaaacag gttctggggc ttgatggcat tggtgaggcc
    32401 ggctggcgcg ccctgcatca gactcatcgc tttgagcata tcttttcctg gcttttatta
    32461 acgccagagc aattacagaa cacgccgggg atcgcgaaaa gtaaaagtgc gcagttatgg
    32521 catcagttta atctggctcg tcagcagcct tttactcgct gggtgatggc aatgggaata
    32581 ccgctaactc gggcggcgct taatgccagt gatgaacggt cctggtcgca acttttattt
    32641 agcacggaac agttctggca gcagctgccg gggactggat cggggcgcgc cagacaggtt
    32701 attgaatgga aggaaaatgc gcaaatcaag aagctgggca gttggctggc tgcccagcag
    32761 atcacaggtt ttgaacctta gtgaccttcg tggctgtagt aaaagaccgg taatcccagc
    32821 ttaagacgta gcgccagtaa acgggcaaaa aagccgaata ccagggtgga gataatcacc
    32881 acatcatggt tagaaacata gtgttgcagc gcgatgtaca gcacggcgga ggcaaatgag
    32941 acacccgcat acaactcttt ctggaatacc agtgggatgc gtttacagaa catatcgcgc
    33001 aaaacgccgc caaacacgcc ggtggttacc gccgcgacaa cggcaataat cgggccgtgc
    33061 cccatatcca gagcaacctg tgcgccgatg atagaaaata ccaccagtcc gagcgcatcg
    33121 agcaccagaa acactttgcg cagataaggc attacaggag caactatagt ggtgagtact
    33181 gcagcggtag cgacgataat cacatattcc gggtgtttga cccagccgag cggatagtgg
    33241 cccagcagaa tatcgcgcac tgaccctccg ccaattgccg tggcggtcgc aataataatt
    33301 acgccaaatg tatccatgcg ccgtcgtccg gccgccagcg cccccgtcat ggcttcggca
    33361 gtaatgccaa ccaaatacaa aatgtgtaac agcatggttc tctccctaaa aatctgtctg
    33421 gaagggtagc gatttgtgcg cattgtcacg attgagattt tttaaggaga gaatagattg
    33481 ataatttgta gttatgtgaa attgctattt tctgtagtaa gaatgcattt ttctgatttt
    33541 gtgataagta aaatgcatta gaaaaagtat ggagtaaata aatatgagga cgaaactata
    33601 tgcgtagcgc cgctgtaatt aacaacggcc tacggagata tgtcgcttac tcgatattct
    33661 gaatctgctc gcgcatctgt tcaatcaaca ctttcagctc gatggcggag tttgtcactt
    33721 cggcgttgat agatttcgac gcaagagtgt tcgactcgcg gttgaactcc tgcatcataa
    33781 agtccagacg acgaccaacg gcttcttttt tcttcagaat gttgtaggtc tctttgacat
    33841 gcgcttcgag gcggtccagt tcttcggcaa cgtcaattcg ttgtgccagc agaaccaact
    33901 cctgctccag acggttgttt tccagttgca cctgagcatc ttccagcttc gctaccagac
    33961 gctcacgctg ccattgcagg atttccggca tatgggcgcg gactttgacc acttcggcgg
    34021 tgacgccttc cagacgctgc tcaatcaaca ctttcagcgc ctgaccttcg gtttcgcgcg
    34081 cgatgataaa gtcatccagg gtgccatcca acgccgcgag aatttcagct gcaatcgcgt
    34141 cgagatcttg ctcctgggct gccatcacgc ccggccagcg tagaatatca accgggttga
    34201 tttctccttc gtcgctctgc atttttaccc agttcgcggc agttaccagc tgtttagcca
    34261 gtttttcgtt gaggatcagc tcaccttgcg cgctaacatc tggctcatag cgcagagtac
    34321 attccacttt accgcgcgtc aggcgagaac gaatacgctc gcgaacgaca ggttcaaggc
    34381 tacggaactg ctccggcaga cgaaagtaag tttccagata acgctggttt accgagcgca
    34441 tttcccaggt tgcgctcccc cattcaccct tgatttcacg ccgggcgtag gcggtcatac
    34501 tgcggatcat agacgttcct gtttataaaa ggagaggtgg aaggattata gccatcgatg
    34561 ccttgtcagg ataggaataa ccgccggaag tccgtataat gcgcagccac atttgtttca
    34621 agccggagat ttcaatatgc gtccagcagg ccgtagcaat aatcaggtgc gtcccgttac
    34681 cctgactcgt aactatacaa aacatgcaga aggctcggtg ctggtcgaat ttggcgatac
    34741 caaagtattg tgtaccgcct ctattgaaga aggcgtgccg cgcttcctga aaggtcaggg
    34801 ccagggctgg atcaccgcag agtacggtat gctgccgcgt tctacccata cccgtaacgc
    34861 gcgtgaagcg gcgaaaggta agcagggtgg acgcacaatg gaaatccagc gtctaatcgc
    34921 ccgtgctctt cgcgcggcag tagatttgaa agcactgggt gagttcacca ttacgctgga
    34981 ctgtgacgtg cttcaggctg atggtggcac gcgtaccgct tcgattacgg gtgcctgcgt
    35041 ggcgctggca gatgcgctac agaagctggt ggaaaacggc aagctgaaaa ctaatccaat
    35101 gaaagggatg gtagccgcgg tctctgtcgg gattgtgaac ggtgaagcgg tttgcgatct
    35161 ggaatatgtt gaagactctg ccgcagagac cgacatgaac gtagtgatga ccgaagacgg
    35221 gcgtatcatt gaagtgcagg ggacggcaga aggcgaaccg ttcacccacg aagagttact
    35281 caccttgttg gcgctggccc gagggggaat cgaatccatt gtagcgacgc agaaggcggc
    35341 gctggcaaac tgatttttaa ggcgactgat gagtcgcctt ttttttgtct gtagaaaagt
    35401 aagatgagga gcgaaggcat gaaaccatat cagcgccagt ttattgaatt tgcgcttagc
    35461 aagcaggtgt taaagtttgg cgagtttacg ctgaaatccg ggcgcaaaag cccctatttc
    35521 ttcaacgccg ggctgtttaa taccgggcgc gatctggcac tgttaggccg tttttacgct
    35581 gaagcattgg tggattccgg cattgagttc gatctgctgt ttggccctgc ttacaaaggg
    35641 atcccgattg ccaccactac cgccgtggcg ctggcggagc atcatgacct tgacctaccg
    35701 tactgcttta accgcaaaga ggcaaaagac cacggtgaag gcggtaatct ggttggtagc
    35761 gcgttacaag gacgcgtaat gctggtagat gatgtgatca ccgccggaac ggcgattcgc
    35821 gagtcgatgg aaattattca ggccaatggc gcgacgcttg caggcgtgtt gatttcgctt
    35881 gatcgtcagg aacgcgggcg cggcgaaatt tcggcgattc aggaagttga gcgtgattac
    35941 aactgcaagg tgatctctat catcaccctg aaagacctga ttgcttacct ggaagagaag
    36001 ccagaaatgg cggaacatct ggcggcggtt aaggcctatc gcgaagagtt tggcgtttaa
    36061 cgaaactcgc cggatgaaaa gtcatccggc gtcatattac tgcaactgtg cggcaattag
    36121 cggccagcgg gcgtcaaaat catccgtcgg gcggtattta aactcgctgc ggacaaatcg
    36181 tgacagcata ccttcacaaa atgccagcaa ctggcttgcc agcagggttt catcggtggt
    36241 gtaaccttca ccctcacgca ttctcttttc acgcaatacc tgacgcaact gcgcttcaat
    36301 acgctcgaac agctggttga tgcgcccttg cagacgatcc tgttcgaaca ttagcgcatg
    36361 accagtgagg atgcgagtca ggccaggatt acgctcacca aaaccgagga gcaacaacac
    36421 gatcagacgc aggcgcgctg tggtgtcttt ctcatctttc agaatcaggt tgatacgagt
    36481 aatcaggcta tcttcgataa actcaatcag gctatcgaac atgcgggtct tactggggaa
    36541 gtggcgatac agtgccgctt cggaaacgcc gacagaggcg gccagttttg ccgtcgtgat
    36601 acgttggctt ccatcgctgg attccagcat cagcgccaga gactgaagta tttcctcgcg
    36661 acggttcctt ttcgcagttt gtttttctgc catgttacaa aatacccctg aaaataagca
    36721 cttgccaggc ggcacccacg ctatgaccgc aaacgaaatg tttgcggcta tgttatgacg
    36781 ttattcggat gcgtatgtgt tactgacgac cagagtgacc aaagccgcct tcaccgcggt
    36841 cggtggcgtc gaaatcttcc accagattaa attcagcctg tactaccgga acaaaaatca
    36901 tctgggcgat gcgttcgcca ggttgaatgg tgaagctgtc ctgaccacgg ttccacacgg
    36961 aaatcatcaa ctggccctga tagtcagaat cgatcaatcc taccaggtta ccaagcacga
    37021 taccgtgctt atgtcccaat ccggagcgcg gtagcatcat tgccgccagt gaaggatcgg
    37081 caatatgaat cgccagcccg gtcggaacca gcgtagtgtc acccggagcc agttctacgg
    37141 cgtcgtcgag acaggcacgc aggtcaagtc cggcagagcc agaggtggca taagtcggga
    37201 gcggaaattc cttcccaacg cgcgggtcca gaatcttaac gtcgattttt ttcatcataa
    37261 cgggtcacga tctcgtcgag taataattgg ccaaggagct ctttgcgctc aagcggtaag
    37321 actttatctc cgtcctgcca gaaaaggtgt aatgcgttgt tgtcgctgtt aaatccttga
    37381 gttggctggg aaacatcgtt cgcgcagatc agatcaaggt ttttacggat acgtttttgc
    37441 cgggcgtatt cttccacatt atttgtttcg gcggcaaatc caacgacgta aggtcgatgg
    37501 tcttttagtg cggcaacgcc tgcgacgata tcggggtttt taaccatttt tattgttaat
    37561 tcatcaccct gcgtggcctg ctttttgatt ttttctgggg ccacggtagc tgcgcgataa
    37621 tccgccacgg cggcgcaacc gataaaaata ttttgctgct gtactgaagc attcacggcg
    37681 gcttccattt ccagcgcggt catcacatca acacggttaa caaacggtgg cgtcggtagt
    37741 gaaaccggac ctgataccag cgtgacgttc gcgccacgac gggctgcggc ggcggcgata
    37801 gcaaaaccca tcttgccgga gctgtgatta gagatataac gcacgggatc gagcggttca
    37861 cgcgtcggac cggcggtaat cataatgttc agatgtttca ggtcgttgac gggcgaaaaa
    37921 tgcgctaccg ccatatccac aatagttaac ggatcgagca ttcgtcctgg gccgatatca
    37981 ccacaagcct gactgccgct gtctggcccc cagatgagca aaccacgtga ggcaagcacc
    38041 tctaaattat gctgggtggc ggcggcacgg tacatctgct ggttcatggc ggggagcacg
    38101 gctacaggcg caggtgtagc cagacaaatc gtcgatacca ggtcattcgc cattccggct
    38161 gcaacacggg caattaaatc tgccgtggca ggggcgagaa tcactaaatc agcccatttt
    38221 cccagctcaa tatggcccat agcggcttcg gctgccgggt ccagcagact gtcggaaacg
    38281 ggataaccag aaaccgcctg caagctaagt ggggtgataa aggcttttgc cgcttcggtc
    38341 atggctacgc agacatcggc cccgcgatcg cgcaaacgac gcaccagttc aggggtttta
    38401 taggcagcaa taccgccgct aacgccgaga acgatttttt taccggccag gctcatgatg
    38461 atttttcctg ttgggtgaca ccagaagttg gcgattttat cacaatactt ttgttgtcgt
    38521 gccttcacct gagattcact ttgcgaggcg ctttccagga ttgaaaactg gccgtcgatt
    38581 taaaggaacg gctatgacag gatgcgagca ccacaaagga ggtgaaggtg aaaaacaatg
    38641 tacagctgtt gatgccgcgc gaaaaaatgc tgaagtttgg tattagcgcc ttaacggatg
    38701 tcgagctgct ggcgctattt ctgcgtaccg gaacgcgcgg taaagatgta ttaaccctgg
    38761 caaaagagat gctggagaat ttcggctctc tttatggctt gttaacctct gaatatgagc
    38821 aatttagtgg cgttcatgga attggcgtgg cgaaattcgc ccagttaaag gggattgccg
    38881 aactggcgcg gcgttactac aacgtacgga tgcgtgaaga aagcccttta ctcagcccgg
    38941 agatgacgag ggaattttta caaagccagc tcacgggcga ggagcgggag atctttatgg
    39001 tgatctttct cgactcccaa cacagggtta taacgcatag ccgtcttttt tccggcacgc
    39061 taaaccatgt tgaagtccat cctcgggaaa ttatccgcga agcgataaaa ataaacgcct
    39121 cggcgctgat ccttgcgcat aatcaccctt cgggttgtgc tgaacccagt aaagcggata
    39181 aactcattac tgaacggata ataaagagtt gtcagttcat ggatttacgc gtgctcgacc
    39241 atatcgtgat tgggcgtgga gagtatgttt cttttgccga acgcggctgg atttaacccg
    39301 ctatgcgcga tccttcggga tctttgtctg ttcgggactt gagcacatcg ctgagtcagc
    39361 gtatactacg ccacctttga gaatctcggg tttggcattt gggcctggca atcgagagtt
    39421 cacatagaac tgcgatgacc gggctgtaaa gcctgacgag gcgccaatac cccatacgaa
    39481 gctcgagcta atttgatttt tggagaatag acatgtcccg agtctgccaa gttactggca
    39541 agcgtccggt gaccggtaac aaccgttccc acgcactgaa cgcgactaaa cgccgtttcc
    39601 tgccgaacct gcactctcac cgtttctggg ttgagagcga gaagcgtttt gtcaccctgc
    39661 gcgtatctgc taaaggtatg cgtgtaatcg ataaaaaagg catcgataca gttctggctg
    39721 aactgcgtgc ccgtggcgaa aagtactaag tacttagagg aaataaatca tggctaaagg
    39781 tattcgtgag aaaatcaagc tggtttcttc tgctggtact ggtcacttct ataccactac
    39841 gaagaacaaa cgtactaagc cggaaaaact ggaactgaaa aaattcgatc cagttgttcg
    39901 ccagcacgtg atctacaaag aagcgaaaat caaataattt ccgctttgat gtaacaaaaa
    39961 acctcgcccc ggcggggttt tttgttatct gcttgccccc atattgactg catctgttca
    40021 ttcctggaga tgctatgcct gaattacccg aagttgaaac cagccgtcgc ggcatagaac
    40081 cgcatctcgt tggtgcaacc attcttcatg cggtggtgcg caacggacgc ttgcgctggc
    40141 cggtttcaga agagatctac cgtttaagcg accaaccagt gcttagcgtg cagcgccggg
    40201 ctaaatatct gctgctggag ctgcctgagg gctggattat cattcatttg gggatgtctg
    40261 gcagcctgcg catccttcca gaagaacttc cccctgaaaa gcatgaccat gtggatttgg
    40321 tgatgagcaa cggcaaagtg ctgcgctaca ccgatccgcg ccgctttggt gcctggctat
    40381 ggaccaaaga gctggaaggg cacaacgtgc tggcccatct tggaccggag ccgcttagtg
    40441 acgatttcaa cggtgagtac ctgcatcaga agtgcgcgaa gaaaaaaacg gcgattaaac
    40501 cgtggctgat ggataacaag ctggtggtag gcgtagggaa tatttatgcc agcgaatcgc
    40561 tgtttgcggc ggggatccat ccggatcggc tggcgtcatc actgtcgctg gcggagtgtg
    40621 aattgttagc tcgggtgatt aaagcggtgt tgctgcgttc gattgagcag ggcggtacaa
    40681 cgctgaaaga ttttctgcaa agtgatggta aaccgggcta tttcgctcag gaattgcagg
    40741 tttacgggcg aaaaggtgag ccgtgtcggg tgtgcggtac gccgattgtg gcgactaaac
    40801 atgcgcagcg ggcaacgttt tattgtcggc agtgccagaa gtaattgatg cgcgccggat
    40861 ggcataccat ccggcataaa ctctacgcta acttcgccat cagcgcctga tggacattct
    40921 ccggcaggaa atgggtgaca tcgccctgat ggcgcgccac ctctttcacc aacgatgaag
    40981 agataaacga ccactctttc gacggcatca gaaacacact ttccagctcc ggcattaagt
    41041 ggcgattcat atgcgccagc tgcatttcat attcaaaatc cgccaccgca cgcaggccac
    41101 gaatcagcac cgtagcgtgt tgattacggg cgaagttcgc catcaaatca ctaaacccga
    41161 ccacttccac gttctccaga tgcgcggttg cctgctgtgc cagctccaca cgctcttcca
    41221 gggtaaacat cggtttttta ctgggactag cggcaatcgc cagaataacg tgatcgaaca
    41281 tttgcgaggc gcgcgtcacg atatcgatat gaccattggt aatgggatcg aaagtacccg
    41341 gataaatcgc ccgtttttgc ataacaacct caatgcgttt tcggtggcag gtaaggttcc
    41401 agcagttgaa gcagacgctg tagtgcgccc tggttttgat acagcacttc aacggcatga
    41461 cggccataga aactacggta atcggcgtcg gtgagtaaag aggaaacctc ttttgcaagc
    41521 gtagtggcat cggtaacggt aatcagcccg cttgcctgct ccagccgcgc gcaaatgtct
    41581 ttaaagttaa acgtatgcgg ccccatcaat accggaatag cgtgtgcggc cgcttccagc
    41641 ggattatgcc caccacgttc aaccagtgaa ccgccaacaa aggcgagatc ggcaatgccg
    41701 tacagtaaca tcaactcgcc catcgtatcg ccaaccacaa cctgcgtgct ggtggagggg
    41761 acttcccctg aagatcgtgt gatatagctt agtccagcct ggcggacaag gttaatcgca
    41821 tccgggaagc gttctggatg acggggtacc aggatgagca ataaattcgg gaattgctgt
    41881 aacaatgcct gatgtgcggc gatcaccaca ctctcttcgc cttcatgagt gctggtggca
    41941 atccataccg ggcggtgtgg tgcccactgg cggcgcagcg tcacggcttt agcagccaac
    42001 tgcggcgtta cagaaatatc gaatttcagg ctaccggtaa cggtcacctg attatttttt
    42061 gcgcccagcg ccacaaaacg tgcaccatct tcttcatttt gggcggcaat cagcgtaata
    42121 cgacgcagca agcggcggac gaatttaccc agtttggcat aacctgcggc cgagcgggca
    42181 gagagtcgcg cgttagcgat caccagcgga attttacgtt tatgtagcgc cgcaatcagg
    42241 ttaggccata gttcggtttc cataatcaac accagtttag ggtcgacttt attcaggaaa
    42301 cggttgagtg catcgggcag gtcatacggc agataaacgt gctgaacatc cttcccgaaa
    42361 gccgattgta cgcgctccga accggttgga gtcatggttg ttacggtaat cggtaaatca
    42421 ggataacgat gacgcagtgc gcgcaccaac gggatcgccg ccagagtttc accgacggag
    42481 acggagtgca gcataatgcc gcctggtttt agcggatggc ggtaaaaacc gtaacgttca
    42541 ccccagcgtt ttcgataggc cggagcctta cgtccgcgca cccagagccg tatccagatc
    42601 agtggctgaa taaggtagag aagggcggtg taaagcaatt cgagcatagt aaatagctga
    42661 cttatggatg tgctggggat tctatgtatt tagctgtggc tttaccatta cttttcccgt
    42721 ttttgactta aatagcaatt tacccgccaa ttcttgctga acatctatac tttttttgta
    42781 tttttatgcg attcattgat ttctgcagta cgtgcaggaa ggaatcgcag agcaacagta
    42841 aaaagaatat ggttgctaat gattttattt gattgatttc tttattgaaa atcaacaatg
    42901 tgcttaaaaa tcattcgggt cggattgccg cgaaagaagt gatacactag cgcgtcaata
    42961 tcagtgcggt atcagtattc aggtagctgt tgagcctggg gcggtagcgt gctttttctg
    43021 cttcacctta atcggataat ctcaacaaaa agagttactt gtggataagc catttcgaag
    43081 aattttgctc attaagatgc gttttcatgg ggatatgtta ttaactactc ccgtcattag
    43141 ttcgctgaaa aaaaattacc ctgacgcaaa aatcgatgtg ctgctttatc aggacaccat
    43201 cccgatcctg tctgaaaatc cagagattaa cgcgctctac ggcataaaaa ataaaaaagc
    43261 aaaagcctca gaaaaaattg ccaacttttt tcatctcatc aaggtattac gtgccaataa
    43321 gtatgacctt atcgttaatc ttaccgatca atggatggtt gctatactgg ttcgcttatt
    43381 aaatgcccgt gtgaaaattt cccaggatta tcatcatcgg cagtctgctt tttggcgtaa
    43441 tagtttcact catttggtgc cgttgcaggg tggaaatgtg gtggaaagta acttatccgt
    43501 gctgacgcca ttgggacttg aatcgttggt gaagcagaca accatgagtt acccgcctgc
    43561 aaactggaaa cgtatgcgtc gcgaacttga tcacgctggt gttggacaaa attatgtggt
    43621 tatccaacct acggcgcggc aaatcttcaa atgctgggac aacgccaagt tttccgctgt
    43681 gattgatgcc ttacatgctc gtggttatga agtcgttctg acgtccggcc cagataaaga
    43741 cgatctggcc tgcgtcaatg aaattgcgca gggatgccag acgccaccag taacggcgct
    43801 ggccggaaag gtgaccttcc cggaacttgg tgcgttaatc gatcatgcgc agctgtttat
    43861 tggcgttgat tccgcaccgg cgcatattgc cgctgcagtt aatacgccgc tgatatcgct
    43921 gtttggtgcg acggaccata ttttctggcg tccctggtca aataacatga ttcaattctg
    43981 ggcgggagat taccgggaaa tgccaacgcg cgatcagcgt gaccgaaatg agatgtatct
    44041 ttcggttatt ccggcggcag atgtcattgc agctgtcgat aaattacttc cctcctccac
    44101 gacaggtacg tcgttatgat cgttgctttt tgtttatata aatattttcc ctttggcggt
    44161 ttgcagcgcg attttatgcg tattgctcag acagtcgccg cccgaggcca tcatgttcgg
    44221 gtttataccc agtcgtggga aggcgaatgc cctgatgtat ttgaactgat caaagtgccg
    44281 gttaaatcgc ataccaatca cgggcgcaat gcggaatatt ttgcctgggt gcaaaaacat
    44341 ttacgtgaac accccgtcga tagagttgtt ggatttaata aaatgccggg gctggacgtt
    44401 tattatgccg ctgatgtttg ttatgccgag aaagtagcgc aggagaaagg ctttttctat
    44461 cgcctgacgt cacgttatcg ccattatgct gcctttgagc gggcaacctt cgaacagggc
    44521 aagccgacac agctgctgat gctgacagat aagcaaatcg ccgatttcca gaaacattat
    44581 cagactgaag cggaacgttt tcatattctg ccaccgggga tttatcctga tcgtaaatat
    44641 agccagcagc cagccaatag ccgtgaaatc ttccgtaaga agaatggaat aaccgaacaa
    44701 caatatttat tgttgcaggt tggttcagac ttcacgcgta aaggtgtcga tcgttccatt
    44761 gaagcacttg cttcgttacc ggattcgctg cgccacaaca cattgctata tgttgttggg
    44821 caggataaac cgcgaaaatt tgaggcgctg gcagaaaaac gcggcgtgcg cagtaatgtt
    44881 cacttcttct cggggcgcaa cgatgtctcg gaattaatgg cggcggcgga tttattactt
    44941 catcctgcct accaggaagc cgcgggaatt gtactgctgg aagcgataac tgcaggatta
    45001 ccggtactaa caacagccgt ttgtggctat gcgcattata ttgttgacgc caattgcggc
    45061 gaggctattg ctgagccatt ccgccaggaa acattgaatg agattttacg caaagcgtta
    45121 acgcaatctt cattgcgcca ggcctgggcg gaaaatgcgc gacattatgc tgatacacaa
    45181 gatttataca gtctgccaga gaaagcggcg gacatcataa cgggtggtct ggatggttga
    45241 acttaaagag ccgtttgcca cgttatggcg cggtaaagat ccttttgagg aagttaaaac
    45301 cttgcagggt gaggtatttc gtgaactgga aactcgccgc actctgcgct ttgaaatggc
    45361 gggcaaaagc tattttctca aatggcatcg cggcacgacc ctgaaagaga taatcaaaaa
    45421 tttactctca ttgcggatgc cagtattagg cgcagaccgc gaatggaatg cgattcatcg
    45481 actgcgggat gtcggcgttg atactatgta tggggtggca ttcggcgaaa aaggcattaa
    45541 tccgctgacc agaacctcgt ttattattac cgaagatctg acaccaacca tcagtctgga
    45601 agattactgt gctgactggg cgaccaaccc accagatgtt cgcgtgaagc gtatgcttat
    45661 taagcgtgtc gcgacgatgg tgcgcgatat gcatgctgcg ggcattaacc accgtgactg
    45721 ttatatctgt catttcctgc tgcacttgcc tttttccggt aaggaagagg agttaaaaat
    45781 ttcagtaatt gacctgcacc gggcgcagat acgtgcaaaa gtaccgcgtc gttggcggga
    45841 taaagatttg attggtttgt atttttcatc aatgaatatt gggctgacgc agagagatat
    45901 ctggcgattt atgaaggttt attttgggat gcctttacgt aagatattat cttttgaacg
    45961 gaatttattg aacatggcaa gtgttaaggc cgagcatatt aaagagcgaa cacaacgcaa
    46021 aggattataa aaatattaat cagtatgtac tggaactaac ttcattatga ctatttattt
    46081 tataaactgg gttgcagatt atgaattaaa aatgatccag tacttgaaaa aaaagcacaa
    46141 gataaaaaat ataacaacac caaaaaaata caactgggtt aataagaaa
//
LOCUS       DAFGPF010000028        45093 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFGPF010000028 DAFGPF010000000
VERSION     DAFGPF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 45093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45093
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.028"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            43..672
                     /locus_tag="LSX49_001770"
     CDS             43..672
                     /locus_tag="LSX49_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001344968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBL7168192.1"
                     /translation="MCEHLITVVEKYGAAERVHLGKQAGNVGRSVTKLPLMGKSLHKT
                     IERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLACRRRGLIVLTDRYPQDQIPGA
                     YDGTVFPPNIEGGRFVSWLASQERKAFHWMASHKPDLVIKLNVDLEVACARKPDHKRE
                     SLARKIAITPQLTFGGAQLVDIDANQPLEKVLIDAEKAITDFMTARGYH"
     gene            complement(721..2220)
                     /gene="pitB"
                     /locus_tag="LSX49_001771"
     CDS             complement(721..2220)
                     /gene="pitB"
                     /locus_tag="LSX49_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HBL7168193.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRFWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGAQVTEFHCHPANTFDAIARVKTMLPGNMESYEPLSV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
     gene            complement(2512..4371)
                     /gene="gss"
                     /locus_tag="LSX49_001772"
     CDS             complement(2512..4371)
                     /gene="gss"
                     /locus_tag="LSX49_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HBL7168194.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHTPLPQGQQ
                     WTRELEMVVENGGYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDQTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK"
     gene            4576..5442
                     /gene="yghU"
                     /locus_tag="LSX49_001773"
     CDS             4576..5442
                     /gene="yghU"
                     /locus_tag="LSX49_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HBL7168195.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFASINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP
                     ALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGG
                     FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGN
                     VVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDAS
                     DFETNTEDKRQG"
     gene            complement(5512..5760)
                     /gene="hybG"
                     /locus_tag="LSX49_001774"
     CDS             complement(5512..5760)
                     /gene="hybG"
                     /locus_tag="LSX49_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HBL7168196.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(5773..6114)
                     /gene="hypA"
                     /locus_tag="LSX49_001775"
     CDS             complement(5773..6114)
                     /gene="hypA"
                     /locus_tag="LSX49_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HBL7168197.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(6107..6595)
                     /gene="hybE"
                     /locus_tag="LSX49_001776"
     CDS             complement(6107..6595)
                     /gene="hybE"
                     /locus_tag="LSX49_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HBL7168198.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDSV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVANPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(6588..7082)
                     /locus_tag="LSX49_001777"
     CDS             complement(6588..7082)
                     /locus_tag="LSX49_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HBL7168199.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKNAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
                     ATHD"
     gene            complement(7082..8785)
                     /gene="hybC"
                     /locus_tag="LSX49_001778"
     CDS             complement(7082..8785)
                     /gene="hybC"
                     /locus_tag="LSX49_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HBL7168200.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(8782..9960)
                     /gene="hybB"
                     /locus_tag="LSX49_001779"
     CDS             complement(8782..9960)
                     /gene="hybB"
                     /locus_tag="LSX49_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HBL7168201.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLQRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(9950..10936)
                     /gene="hybA"
                     /locus_tag="LSX49_001780"
     CDS             complement(9950..10936)
                     /gene="hybA"
                     /locus_tag="LSX49_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HBL7168202.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINSPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(10939..12057)
                     /gene="hybO"
                     /locus_tag="LSX49_001781"
     CDS             complement(10939..12057)
                     /gene="hybO"
                     /locus_tag="LSX49_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HBL7168203.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMVESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(12246..12533)
                     /locus_tag="LSX49_001782"
     CDS             complement(12246..12533)
                     /locus_tag="LSX49_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HBL7168204.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(12652..13539)
                     /locus_tag="LSX49_001783"
     CDS             complement(12652..13539)
                     /locus_tag="LSX49_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBL7168205.1"
                     /translation="MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKYAVGGMTA
                     LALFDLLKSNYALATQVEFTDPEIVAEYITYPSPNGHGEVRGYLVKPAKMSGKTPAVV
                     VVHENRGLNPYIEDVTRRVAKAGYIALAPDGLSSVGGYPGNDDKGRELQQQVDPTKLM
                     NDFFAAIEFMQRYPQATGKVGISGFCYGGGVSNAAAVAYPELACAVPFYGRQAPTADV
                     AKIEAPLLLHYAELDSRINEGWPAYEAALKANNKVYEAYIYPGVNHGFHNDSTPRYDK
                     SAADLAWQRTLKWFDKYLS"
     gene            13696..14736
                     /gene="gpr"
                     /locus_tag="LSX49_001784"
     CDS             13696..14736
                     /gene="gpr"
                     /locus_tag="LSX49_001784"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HBL7168206.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTEELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(14776..15270)
                     /locus_tag="LSX49_001785"
     CDS             complement(14776..15270)
                     /locus_tag="LSX49_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HBL7168207.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            15461..16345
                     /gene="yghA"
                     /locus_tag="LSX49_001786"
     CDS             15461..16345
                     /gene="yghA"
                     /locus_tag="LSX49_001786"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HBL7168208.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(16384..16809)
                     /gene="exbD"
                     /locus_tag="LSX49_001787"
     CDS             complement(16384..16809)
                     /gene="exbD"
                     /locus_tag="LSX49_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HBL7168209.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(16816..17550)
                     /gene="exbB"
                     /locus_tag="LSX49_001788"
     CDS             complement(16816..17550)
                     /gene="exbB"
                     /locus_tag="LSX49_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HBL7168210.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            17802..18989
                     /gene="metC"
                     /locus_tag="LSX49_001789"
     CDS             17802..18989
                     /gene="metC"
                     /locus_tag="LSX49_001789"
                     /EC_number="4.4.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HBL7168211.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFVEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
                     MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNDEELANYLDNFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGKIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            19129..19788
                     /locus_tag="LSX49_001790"
     CDS             19129..19788
                     /locus_tag="LSX49_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBL7168212.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(19828..20727)
                     /gene="yqhC"
                     /locus_tag="LSX49_001791"
     CDS             complement(19828..20727)
                     /gene="yqhC"
                     /locus_tag="LSX49_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YqhC"
                     /protein_id="HBL7168213.1"
                     /translation="MKREEICRLLADKVNKLKNKENSLSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCVAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            20921..22084
                     /gene="yqhD"
                     /locus_tag="LSX49_001792"
     CDS             20921..22084
                     /gene="yqhD"
                     /locus_tag="LSX49_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL7168214.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFF
                     EQLGVLTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            22189..23016
                     /gene="dkgA"
                     /locus_tag="LSX49_001793"
     CDS             22189..23016
                     /gene="dkgA"
                     /locus_tag="LSX49_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HBL7168215.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRS
                     IDTAAAYKNEEGVGKALKNASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVKAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIVENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
     gene            23216..24142
                     /locus_tag="LSX49_001794"
     CDS             23216..24142
                     /locus_tag="LSX49_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HBL7168216.1"
                     /translation="MKIILLFLAALASFTVHAQPPSQTVEQTVRHIYQNYKSDATAPY
                     FGETGERAITSARIQQALTLNDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQTD
                     ADHADAIVRFRIFQDDKEKTSQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLA
                     AIASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDM
                     PIERQFIYDNPICFGEESLFSRVDEIRVLEKTTDSARIHVRFTLTNGNNEEQELILQR
                     REGKWEIADFIRPNSGSLLKQIEAKTAARLKQ"
     gene            24193..24450
                     /gene="yqhH"
                     /locus_tag="LSX49_001795"
     CDS             24193..24450
                     /gene="yqhH"
                     /locus_tag="LSX49_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HBL7168217.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKINQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(24492..26711)
                     /locus_tag="LSX49_001796"
     CDS             complement(24492..26711)
                     /locus_tag="LSX49_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBL7168218.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKS
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICSHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRLQNAGAKKRPKAAVGR"
     gene            26963..27712
                     /locus_tag="LSX49_001797"
     CDS             26963..27712
                     /locus_tag="LSX49_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCD domain-containing protein"
                     /protein_id="HBL7168219.1"
                     /translation="MEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNT
                     SRTTIREAIIMLELKGVLNVKQGSGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVI
                     ESNITGFAASQISFNELQELKKIIGLQEKAIAAESDKFEDLDHRFHSIIAEATQNRVL
                     IKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREAS
                     WRHLENSKNELIKIFKQDASISDFDDFFFAR"
     gene            28035..29507
                     /locus_tag="LSX49_001798"
     CDS             28035..29507
                     /locus_tag="LSX49_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL7168220.1"
                     /translation="MSGNESIDAAHYDQVTTWPRGGLQADIVHIGFGAFHRGHQAVYT
                     DLTNQLSDTHWGIFEINLFGDAQLIENLNAQNGLFSVVETSASQSTSRLVRSVTGGIH
                     TPVDGIAAAIQKLTEPQVKIVSLTITEKGYCLDSQTRSLDLTNGLIKHDLQNPDAPQS
                     AIGLIVCALQQRKAAGLAAFSVLSCDNLPDNGHLTRNAVLGFARQLDQPLAQWIEENV
                     SFPGTMVDRIVPAMTESQFALLETKTGYADPCGIVCESFRQWVIEDNFVHGRPQWDKA
                     GAMFVSNVQPYEEMKLRMLNGGHSFLAYNGSLAGYEFIWQCMEDADFRSITRQLMINE
                     QARTLNPDLNIDAQEYADLLIERFSNRNVAHRTGQIAMDGSQKLPQRALTPWLKLHQQ
                     KQNNAVLSLLVAGWLHYVIEAVEKSQSVADPMNEQFQALIKEQQDAWQQALALLHLSA
                     IFGDLSNHQPFINEIKIAFANIKNKGIKATISQLLSDEQK"
     gene            29504..30520
                     /locus_tag="LSX49_001799"
     CDS             29504..30520
                     /locus_tag="LSX49_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000853917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL7168221.1"
                     /translation="MKTLICQQPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAF
                     AGRQPFFSYPRVLGHEICAEAVSRGSQCQTAQSGQRYSVIPCIPCGECAACREEKTNC
                     CERVSLYGVHQDGGFSEYLAVREDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKA
                     EQNVLVIGAGPIGLATAAIARAKGAHVVVADIDCQRRQHVVDHLAINAFNPTQEDFIA
                     ALREAFGGELACVVLDATGNKASMSHDVNLIRHGGKIVFIGLYIGELVIDDPTFHKKE
                     TTLLSSRNATREDFALVIELMRSNKIHENLMKNQAFNFFSVGEDYQRNVVENKNMVKG
                     VITF"
     gene            30531..31541
                     /locus_tag="LSX49_001800"
     CDS             30531..31541
                     /locus_tag="LSX49_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ldh family oxidoreductase"
                     /protein_id="HBL7168222.1"
                     /translation="MTTVYVSEENLKSLVHHKLHTAGLDTDTTQQVTDVLVHADITGV
                     HSHGVMRVEHYCTRLAAGGLNKAPQFSIEQISPSVAILDSDDGMGHSALISATEHAIK
                     LAQQEGLGFVSVKNTSHCGALSYFAEMITNKGLVAIVMTQTDTCVAPHGGAERFLGTN
                     PIAFGFPVENSHPMIVDMATSATAFGKILHAKETGKHIGEGLAIDKNGYGTTDPYKIE
                     NLLPFGQHKGSGIALAIDALTGVLMNANFGNHIVRMYGDYDKMRKLASLVIAIDPKKL
                     GNPVFAKTMAKMVTELHAVKPAPGVEKVLAPNDPQMHYKEKCQQEGIPVPAGIFHYLA
                     EN"
     gene            31614..32597
                     /locus_tag="LSX49_001801"
     CDS             31614..32597
                     /locus_tag="LSX49_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBL7168223.1"
                     /translation="MKALRPLTASLMLLTSCLLISNTTLAKTTLKLSHNQDKSHAVHK
                     ALSYLADKTKEYSNGELVIRIYPNATLGNERESLELMNSGALQMVKVNAASLESFAPD
                     YSLFSLPFLFRDRDHYYRVLQSDLGKKILNSSESKGFVGITYYDGGARSFYSNKPITK
                     PEDLAGMKIRVQQSPSAIAMMKALGGVATPMAQGELYTALQQGVVDGGENNTVVYADM
                     RHAEVAKVYSRDEHTMVPDVLIISTDVLNKLGDKERTALLKAADESMMQMKDVIWPAA
                     EKEAYDKMKGMNATVVDVDKSAFKERVKPLYDEFKAKDAQSAKNLELVESM"
     gene            32639..33121
                     /locus_tag="LSX49_001802"
     CDS             32639..33121
                     /locus_tag="LSX49_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL7168224.1"
                     /translation="MRTLTHILNKILAGCCCIILAIMVFCVTWQVIARFIFNAPSTVL
                     DEFTQILFMWMILLGGVYTAGLKKHLAIDLLAQKLPAASVLTLDSFIQIIITVFAVIF
                     MIYGGNIVVEKAQHVGQISPVLKWPMDKVYWVMPVSGLILVWYSVMNIIDNYRKRNFH
                     "
     gene            33132..34436
                     /locus_tag="LSX49_001803"
     CDS             33132..34436
                     /locus_tag="LSX49_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL7168225.1"
                     /translation="MDFEYIYPVLILFGSFAVMLAIGVPITFAIGLSSLLSIITALPP
                     DAAISVISQKMTVGLDGFTLLAIPFFVLAGNIMNTGGIARRLVNLAQALVGRLPGSLA
                     HCNILANTLFGAISGSAVASAAAVGGIMSPLQEKEGYDPAFSAAVNIASAPIGLMIPP
                     SNVLIVYSLASGGTSVAALFLAGYLPGILTAVALMFVAALYARRHHYPVAERINYRQF
                     LQVFRESIPSLMLIFIIIGGIIAGVFTPTEASAIAVIYSLALAMIYREITLKKLNDIL
                     LDSVVTSSIVLLLVGCSMGMSWAMTNADVPELINELITRVSDNKWVILFIINIILLIV
                     GTFMDITPAILIFTPIFLPIAQHLGIDPIHFGIIMVFNLTIGLCTPPVGTILFVGCSI
                     GKVSIDRAIKPLLPMFLALFVVMAIICYFPQLSLMLPGLFST"
     gene            complement(34507..35919)
                     /gene="ftsP"
                     /locus_tag="LSX49_001804"
     CDS             complement(34507..35919)
                     /gene="ftsP"
                     /locus_tag="LSX49_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HBL7168226.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(35994..36731)
                     /gene="plsC"
                     /locus_tag="LSX49_001805"
                     /gene_synonym="parF"
     CDS             complement(35994..36731)
                     /gene="plsC"
                     /locus_tag="LSX49_001805"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HBL7168227.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAENYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(36966..39224)
                     /gene="parC"
                     /locus_tag="LSX49_001806"
     CDS             complement(36966..39224)
                     /gene="parC"
                     /locus_tag="LSX49_001806"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBL7168228.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDIACYVAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAVIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGI
                     LASERKMNNLLKKELQADAQGYGDERRSPLHEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(39362..40969)
                     /locus_tag="LSX49_001807"
     CDS             complement(39362..40969)
                     /locus_tag="LSX49_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL7168229.1"
                     /translation="MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPG
                     TLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQ
                     WSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKAM
                     DDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDKWV
                     VNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIE
                     KSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATT
                     LTPPEVKGFSATTFDELQKPMSERVAMAKVLLKQAGYDASHPLRFELFYNKYDLHEKT
                     AIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKS
                     DSEENVGHWKNAQYDALLNQAAQTADATKRNALYQQAEVIINQQAPLIPIYYQPLIKL
                     LKPYVGGFPLHNPQDYVYSKELYIKAH"
     gene            complement(41078..41560)
                     /locus_tag="LSX49_001808"
     CDS             complement(41078..41560)
                     /locus_tag="LSX49_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBL7168230.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPDAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTIWGIIRHWLPASGEKMRKAPILFHYTNLAEGMTEQRLEMDVYVPLA
                     "
     gene            complement(41613..42005)
                     /gene="ygiW"
                     /locus_tag="LSX49_001809"
     CDS             complement(41613..42005)
                     /gene="ygiW"
                     /locus_tag="LSX49_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HBL7168231.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            42157..42816
                     /gene="qseB"
                     /locus_tag="LSX49_001810"
     CDS             42157..42816
                     /gene="qseB"
                     /locus_tag="LSX49_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HBL7168232.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            42813..44162
                     /gene="qseC"
                     /locus_tag="LSX49_001811"
     CDS             42813..44162
                     /gene="qseC"
                     /locus_tag="LSX49_001811"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HBL7168233.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDG
                     DNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
                     AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRP
                     LVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKAL
                     LQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQANID
                     VRLTLNANGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGV
                     TPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVDFGNAKQGGFEAKVSW"
     gene            complement(44208..44540)
                     /locus_tag="LSX49_001812"
     CDS             complement(44208..44540)
                     /locus_tag="LSX49_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2645 family protein"
                     /protein_id="HBL7168234.1"
                     /translation="MLKKQLLSIFEALLYIMLTYWLIDSFFAFNKYDWMLESGDNICS
                     IPSVSGEDRILQAMIAAFFLLTPLIILILRKLFMREMFEFWLYVFSLVICLGCGWWLF
                     WGRFIFCY"
     gene            complement(44547..>45093)
                     /locus_tag="LSX49_001813"
     CDS             complement(44547..>45093)
                     /locus_tag="LSX49_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HBL7168235.1"
                     /translation="YNRDKIIKYAYAAGIRPELLGGVAWIESGGMPENYKFQIYETKR
                     MIGLLDMPENKTSFGSMGIQIRTAAITLGLDPSELTTRNQLELATCLMEDDFTFQIAA
                     TYLRDLVLFDYPSSATLYMTNEQYIMAGIRYNRGVERDLGFFICLINNLPARDTDDYK
                     FISYGMRLLEIREHIKKLINE"
BASE COUNT        11400 a        11634 c        11081 g        10978 t
ORIGIN      
        1 ttaattgccg ttattggtag cgatggttca ggcaagtcaa cggtgtgtga acatctcatt
       61 accgttgtcg aaaaatatgg tgctgccgaa agagttcatt taggaaaaca ggccggaaat
      121 gtcggtcgtt cagtgacaaa attaccgttg atgggaaaat ccttacataa aacaattgaa
      181 cgaaatcagg tgaaaacagc aaaaaaattg ccaggaccag ttccggcgct ggtaattaca
      241 gcgtttgtcg cccgtcgctt actgcgcttt cgtcatatgc ttgcctgtcg tcgtcgcggg
      301 ttaattgttc taaccgaccg ttatcctcag gaccaaattc ctggcgctta cgatggtaca
      361 gtgttcccac ctaacattga aggtggtcgt tttgtctcat ggctggcaag ccaggaacgt
      421 aaagcgtttc actggatggc gagccataaa cctgatctgg tcatcaaact caatgttgac
      481 cttgaagttg cctgcgcgcg taaacccgac cataaacggg aatcgctggc gaggaagatt
      541 gccataacgc cacagttaac ctttggcggt gcacaactgg ttgatatcga tgctaatcag
      601 ccactggaaa aggtgctgat tgatgcagaa aaagcgatta cggattttat gaccgcgcgt
      661 ggttatcact agtcaaaaat ggaaatgccc gatcgccagg accgggcatt ttcaggaagg
      721 ttaaatcaac tgcaatgcta tccagtacaa cccaccagaa agaaaaatcg ccgccggtaa
      781 agtaaacacc cacgccatca ggatgctggt taccgtttta cgctgtaacc caccgccgtc
      841 caccaccatc gttcctgcta cggcagatga gagtacgtgt gttgtggaga cgggcatccc
      901 aatataactg gcaaggccga tagacactgc cgccgtcatt tgtgccgcca tgccttgcgc
      961 atacgtcatg ccgcgcttac caatcttctc accgatggtc atcgctacac gacgccagcc
     1021 aatcatggtg ccaatgccga gcgccagtgc tactgccatg atgatccata ccggtgcgta
     1081 ctcaatggtg cttaacatat cgctgcgcag ttttttcagc aggttctggt cttctttact
     1141 gacgcctggc agtttcgcca gcttcgcgga agtatcagag atgcacagca taatgcggcg
     1201 cagctggctg cgctgactca cgcttaacgg ctcgtagctt tccatattgc ctggcagcat
     1261 cgttttaacg cgcgcaatcg catcaaaggt atttgccgga tgacagtgaa actccgtcac
     1321 ttgcgcgcca tcagtcgatg ccgcaggcaa tggaggttcc atcgcaatca acttctgcgg
     1381 cagttcagga tgctgttgca ggtagtgttc gaagttggtg acggcatcgc gggtacgggt
     1441 aatttcatag ccggacgcgt tcatattgac gacgaagcca gcaggggcaa tccccaccag
     1501 taccagcatt accaggccga tccctttctg cccgtcgtta gcgccgtgcg aaaacgccac
     1561 gcccgcagcg gaaacaatca gcgcaatacg cgtccagaat ggcggcttac gtttgccttt
     1621 tttctttttg cgatcttccg gaatgcggtg aatacggtca cgctttttcg tcccgctcca
     1681 gaaacggcgc agcaggaaaa tcagaccacc cgcaatgacc aggccgacga taggggaaac
     1741 aatcagcgag gagaaaattt tggtcacttc acgcaggttt aacgcatcca tcaccgatga
     1801 gccggttaac agcgcgttgg ttaaaccgat gccgataatc gcaccaatca aggtgtgcga
     1861 actggaggcc ggtaaaccaa agaaccacgt tcccaggttc cagataatcg ccgccagcag
     1921 catggaaaag accatcgcca ggccgtgagt tgaccccata ttcagcaaca aatcggttgg
     1981 taacatatgg acaatggcat aggcaacgct aagtccgccc aataacacgc caaaaaaatt
     2041 aaaaaatgcc gccatcacca cagcaagttg tggttgcatg gcacgagtat aaataacggt
     2101 tgccaccgca ttcgccgtgt catgaaaacc attgattgct tcgtagaaca acacaaatgc
     2161 cagagcaagt aataacaaaa gccctgtgta tatatcaagg ccaacaaata aatttagcat
     2221 atattagatt acgccatttt gaatttacga acggacgcat tatcagtgac tttaacggca
     2281 tgggcaaagt gaaatatcat tttttaacga taaaaagcgt gttatttctt gtgtatcaga
     2341 caataagcat tcattcaaaa cctttagaaa taatcaaaac acaggtattc tgctggttaa
     2401 tatattcaca tataaaatga ataaatattg gaatatataa atattgaatg ttttgattaa
     2461 tccccgtact gattattctt cataatcagt acggggttgc tacaacatgt attacttttt
     2521 caccacaatt aacggttcaa tatcactctc ttttttgatg accagtgatt catcaccgcg
     2581 caaacacgtc ccaccgtagt tgccgccaac ggtgaaggta catacctgaa tgtatttacc
     2641 gtccactttc ggcaaacacc acagttgctg gtaaatattt ttctgttcgg caaatttacc
     2701 actggtctga tcaagcacct cttcatgatg gctgaccagg tcaatgttgc taccacagcg
     2761 cccggcaatc ggtttaacgg cataaccggt tttcaccagc tcatcattca cggtgaagtc
     2821 agtatccaac agataacgat ggtgcgggaa cagagaccag aggatcggca gaatcgcttt
     2881 gttaccgggg atcaccgtcc atagcggctc aaaaaccaac acttccgggc gcagcaatac
     2941 gtcgataaga cgcacttcat tttgtggatg cccggtacgg atcggcactg cggcaaattc
     3001 acggtcgctc acttcgcgga tttgatcaaa tgccgtttcc cacgcccagg ttttccatac
     3061 gcagttaacc agtcgccctt ccccatcaat cagttgcccg gcagcatccc agcccagttc
     3121 atccaaccca cgcaagatac gcgtttcaaa gcccgcctgg tgcagcgcct gctccataaa
     3181 ctgcgcgtga tagttttcct cgatatcttt gtcctgcatg atatggacaa acggacgtgc
     3241 acgactgtgt ttccacgcgc cagccagttc gttaatcagt ccttccgcag gattgaagcc
     3301 gttgccttta tagccctgct ccgcccaacg ttcgaggatc aagcccgctt cggtatgaca
     3361 ggaggcagaa tcggcgttgt attcgtagac tttcaggcca cgttcatcca tgcagaaatc
     3421 catacgacca gtgatcatat gatgacggcg acgctgccag gagagacgca aacgtggcca
     3481 gaggattttc ggaatgtcaa acagcgccag caggttgtca tctttcagca ccttgtcggt
     3541 ggcgtgaaga tacatcaggt gcagctcgtt ggtggcttta atcagctcct gctcggcact
     3601 ctcggtaatg gtgtagtaat gatacggatc ctgattgatc acctggccgt tggcctgtac
     3661 ataggcgttt tgcagcggat ctttttcatc cagccattta ccgtcaaact ggcctttgtt
     3721 ttccagacgc gccccgctga ttttcagcag ttcgcctgca atttccggct gtggcaagct
     3781 gtattcggta tcttccgtct ggatcatcca gcccagaata gtggtgtcat cgaaggtgtc
     3841 tttcagggta tagccgccgt tttcgaccac catctccagc tcgcgtgtcc actgttgccc
     3901 ttgcggcaac ggggtatgaa tcacgttctg ttccgcaata cggactttgt tgccatgcaa
     3961 ttgggtaatg atggcgacat ggccagtgtc tttaaattca ccgcctttat cccagataag
     4021 aagcgccccc gctaccggtg cacgcggcga accgttagga aatgcctgca atggcaggat
     4081 gttgtcattg accacttcac gcaggaagcg cagtgagaaa atctcccatg ccatacccac
     4141 gtcagtgaag actacaccgt agttcagaaa gagaaaacgg cgagcaaatt caacgcattg
     4201 ccatttgtgg cccatatatt catcgtcgat atagctacgg aatacggcgt catcttcgta
     4261 ttcctgcgga tcgagagaac tgtaatctga agagtagatt gctaccccac ctggggcgta
     4321 gcccaataat gtcccgaacg gggcatcctg gctggtcgtt cctttgctca tcactttacc
     4381 tttaacaata caacctaagc agttggcgta attgttgtgc tctgattacc tgctcagcga
     4441 cattaaccgg acagaggtca gactaatcat acacctcatc gcagcggctg gcgcaaaggg
     4501 ttaaaaaatt cacattctgt acagcaagtg acctgctaca ctgcttcaac actaccactc
     4561 agaaggcaac tcactatgac agacaatact tatcagcccg cgaaagtctg gacgtgggat
     4621 aaatccgctg gcggcgcgtt cgccagtatc aatcgcccgg tttctggtcc gacgcatgaa
     4681 aaaacgctgc cggtgggcaa acatccattg caactttatt cgctgggaac gccgaacggt
     4741 cagaaagtaa cgattatgct tgaggagctg ctggcactgg gcgttactgg tgcagagtac
     4801 gacgcctggc tgattcgtat tggcgatggc gatcaattct ccagcggctt tgtcgaagtg
     4861 aacccaaact cgaagatccc ggcgctgcgc gaccataccc ataatccacc gatccgcgtg
     4921 tttgagtctg gatcgattct gctttatctg gcggagaaat ttggctactt cctgccgcag
     4981 gatttggcaa agcgtactga aacgatgaac tggctgttct ggttacaggg cgcggcaccg
     5041 ttcctcggcg gtggttttgg tcacttttac cattacgcgc cggtgaaaat tgagtacgcc
     5101 atcaaccgct ttaccatgga agccaagcgc ctgctcgacg tgctggataa gcaactggcg
     5161 cagcacaagt ttgttgcggg cgatgagtac accattgcgg atatggcgat ctggccgtgg
     5221 tttggcaacg tggtgttagg cggcgtgtat gatgccgcag agtttctgga tgcgggcagt
     5281 tataagcacg tgcaacgctg ggcgaaagaa gtgggcgaac gtccggcggt gaagcgtggg
     5341 cgtattgtta accgcaccaa cgggccgctg aacgagcagt tgcatgagcg ccatgacgcc
     5401 agtgatttcg agacgaatac ggaagataag cgtcaggggt aagtcgcaac attggcaggc
     5461 ttatcgctat gtagccggat aaagcattta cgccgcatcc ggctttaatc atcacgcgct
     5521 ggtaatgtcg taatccattt ggcgcagtgc gtctaatgtg gctttggctt catcttcgtc
     5581 gatgatgctc atggcaaatc cgacgtgtac cagcacccac tggcccagca gatcggcagg
     5641 gttaccttca caaatcaggg cgatattcac gtcgcgcttg ataccacata cttcaacctg
     5701 cgcaagctgg tgaatatctt caccgacagc cagcacctgg cctggaacgc caatacacat
     5761 tgttaactcc agttattcaa cttcaatact tttgacgatc agcgaatcgc cggtatcgac
     5821 acgcaaccgc tcgccatgac agagcggaca ctgcgcatcg tgctgatgaa tctccaccac
     5881 ctggctgcaa tcccagcacc aggcctgggc gggtttatag acgatatgta aatcgcaccc
     5941 ttgcgccacc gttccgtggc agacaatttc aaaactaaaa cggacggcgc tctcctcaac
     6001 gcaggagagc gcgccaattt ccagccacac ggcggtgacg cgcttaacat cgtgctgctc
     6061 cgcctgccgt tggataattt caacggcgct ctggcaaagc gacaactcat gcattttcgc
     6121 cactcctgcg accaaacagc agggcgcgac gccctgcgtg tggtacatcc ggattagcga
     6181 ccggtagcga aaggatcatc cgcgcgcagt catccgtcag gcgttggccc tcttcaatcg
     6241 acatgctatg cgaaagcggt gacatcagcg aacaggagag atattgagaa acactgtcca
     6301 gttcgccaac ggtaaaggtc atagtgccat acggcagttg cagaccaatt ttttcactca
     6361 ctttgcgcag cggccagagt tgatccgggc cggggaagat aactgcactc agcatccacg
     6421 gggtgatcac acaccccgtc cactgacctt cgaacagcgt aaagtcagaa acatacaccg
     6481 gcattgaggg atgcagaaaa gagagatcgt gcatcgaacg ccgggcaatt tcttcaaacg
     6541 ctgcctgtac ttgcgccttc ggggaggtct ggaaacctgc tatctcttca gtcatgagtc
     6601 gcctcccgtg ggatagcttc cacgcctgat tcgcgcagcg cagccagaac ctgctcaagc
     6661 gcaggttcaa tcattgcttc aaccgtcggc gttaagccga tgtgcggctc cagcgattcc
     6721 gggatcacac cgaccagcgt cagctttttc ggaaactcgc cggtgaagcg cagggccgac
     6781 aatacgtcgg ccaggccaag ctgatgcgga gagattttgt tggtaaacaa cgccggaact
     6841 tcttcatccc gcaggatcat catcgttccc ggcgcgttct ttttcgacac aatggcatcc
     6901 gcaataatca gatgatcgcg atttgccatg tcgccaagca gctccattcc cgccgtgccg
     6961 ccatcgagga tctcaacata atccggcaga atgtatcgtt gctctaacgc ttcaacaatc
     7021 cgcacaccga tggcttcatc ggtcagcaaa atattgccga cccctaagac taaaatacgc
     7081 attacagaac cttcactgaa accacttcgt tgccgtcggc atccactacg tgtaccgcac
     7141 aggccatgca cgggtcgaag gagtgaatgg tacgcaccac ttccagcggt ttattcggat
     7201 cggcaaccgg tgtacccacc agcgactgct cgtaaggacc gacgtcatca ttgaagttac
     7261 gcggaccaga gttccaggtt gatggaacaa ccgcctggta gttgctgatg ataccgtctt
     7321 taataaccat ccagtgagag agcataccgc gcggcgcttc gaggaagcca acacctttga
     7381 actcacccgt tgccggaatg ttcggcttca caaaggtggt gtgatcgcct ttgccgatat
     7441 tggtgatcag tgcactgtat tggttttgca ggatatcctg caattcacag cagtgaacgg
     7501 tacgaccaat aatacggccc agcgtggagt gcagctgtgc cacttccagc gtgttgccag
     7561 tcagtttctg ataaatcgca acgatttcat tcagtttgtt ctgggtagat tcgcgacctg
     7621 ccgccagttt caccagcata ttagccagcg gacccacttc taccgttttg ccgtagaaag
     7681 tcggcgattt cacccaggaa tatttaccgt catcagacca accgtcgtaa gccggaatgg
     7741 tggtaccttc ccacggtgcc tgcggcgctt cgtctttata ccaggagtgc ttcgcgcttt
     7801 cctgaatgcc tttgatcagg tattcatcgg aatgagaagt gatcggacga tacgaggaca
     7861 gatccgcatt ctcaatgtag ccgcccggga acaggaagct gccgtttttg ctgtcggtcg
     7921 ggaattccgg cacgctcagg tagttcaccg cacctttacc gcgcgtcagc cattccgggt
     7981 agaacgcggc gataactgcg gtatcaacct tataaacctg ttcaacaaag tcgctcagct
     8041 tgtcgatgaa agacttgatg tacatcaggc gctcaaggtt cagcacgccc aaaccgtcga
     8101 ggttgattgg gttagcgacc ccgcctaccg ccaggttctg aatgtgcggc gttttaccgc
     8161 ccagcagcgc cacgacgcgg ttagcgtcac gctggcactc cagcgcctgc aggtagtgcg
     8221 ctaccgcaat caggttcact tccggcggca gtttcatcgc cgggtgaccc cagtagccat
     8281 tggcgaaaat acccaactga ccgctggcaa ccagatcttt aatcttgttc tgaactttgg
     8341 tgaactcttc cggactgttc agatgccagg tcgaaacgcc tttcagcatt tcagaggctt
     8401 tggttgggtc agcttgcagt gcagaagtga tgtccaccca gtccagcgcc gaaagctgat
     8461 agaaatgaac gatatggtca tgcgtggtgt gcgcagccag aatgatgtta cggatgtatt
     8521 gcgcgttaac cggaacgtcg atattcagcg cactttctgc cgcacgaacg gaagacagcg
     8581 cgtgagtggt agtacatacg ccacagatac gttgcacaat catccatgca tcgcgcggat
     8641 cgcggttttt cacgatctct tccatgccgc gccacatggt accggaagcc catgctttcg
     8701 aaacgacgcc attttcgatt tcgcaatcga tgcgtaaatg cccctcaata cgggttaccg
     8761 gatcaatagt aattctctgg ctcatgcttt gctcgcctca tgacgattat gatcgttttg
     8821 ttttaaagga ggaagtatcg gcagtagacg aatgagtacg atgtaagcgc aaatctcaat
     8881 agccacaaaa ccaatagaaa tcaacagttc ttcccaggtc gggaagtagg cgtaaccgcc
     8941 gcccgggttg aatgccacca gcgaataggt cagacgccag gttgcacaac ctaacagtgc
     9001 gctcagtgct gacaggaaca gcatgcggga atcattacgc agcttcgcca cacgcagaac
     9061 gaccagcggg aagagcatca gcaggacttc aatccagaac atcacggagt agaagtcacc
     9121 ggcaaacgct aacgacagct tgtcgcgata gataagctcg ccaaagcgca gcacgatgaa
     9181 aatcgccagc aacacactga tggtgttggt cagcttgacg aacaggctct tttcatccgg
     9241 accgttgcca cgcagacccg cctgcaccag tgaaccttca aagatgacaa tcgagaagcc
     9301 catgatgaac gccgtcagca gcgagaacag cggcaacatt tcatagctct gccacagcgg
     9361 atgcaccttg tagcccgccg agatcatcag cgaccccatt gaagactggt gcatggtcgg
     9421 cagcagcgca ccgagcgcga tgatgaagaa catcaccttg ttcagacgct gtagcgacac
     9481 cttccagccc agacgttcaa acagtgccgg agcaaactcc agtgccatca cgccgatata
     9541 gatggtcata cagaccgccg tctcgaacag taccgagttc acgttgaagt gacccggaat
     9601 gtagaagtac ggcaggttcc agtagcgacc cacgtcgata gtgatcgaca agccacctag
     9661 tgagtaacca aacagactcg ccaacagcgc cggacgcacc agcggatggt attgcccacg
     9721 gttaaagacg tataccgccc acgccagcgc ccagccgcca caggcaaagc cggtgccgat
     9781 caacaggtca aacgcgatcc acacgcccca cgggaagccg ccgttcaggt cagagacaga
     9841 gcccagaccg aacaccagac gcttcacaat caggagcata cagatgacga ttaacggtcc
     9901 aaaaatcatg accggtttac tgatgatttt gccgcccagc ggttgtggat catgactcat
     9961 gatcgtctcc tccgtcgtga tggtcgtttt tggtgttgcg acgaaccagc acggttaagc
    10021 ccgccagcac agccagtggt agcatcatgc ctttatacag ggtgtgttga atattttcgg
    10081 aacgcgcacc ggtagaaaga tcgtccagtt tcggcaggtc gagattttca taaggcacac
    10141 ccgtcagtac cagaacctga gtaccgccgc cctctttctc gccgtacaga tgcggataat
    10201 atttcggcac cgtatgcagg taagtgtcgc cagatttcag cgtctgacgc ggatagtggt
    10261 attcgctgcc aggcttcagc gccagacgtt ttttcgcctc cgccatcagc tcttcacgcg
    10321 taccaaaaat caccgcgccc gccgggcaca cttctacgca gccaggcaga ccgcctttat
    10381 cgagacgttc cacacctttc tggttgcaca actcgcactt atgcagcgca ccaaacgggt
    10441 tgttgtagtc gtacttcggc acgttgtatg ggcaggcgac catgcagtaa cggcagccgg
    10501 tgcacacatc tttgtcgtaa tggacaatgc cggttttcgg atcttttttc agcgcagaga
    10561 ccgggcacac agagacacag ttcggatcga cgcagtgcat acactgtttc ttaatgtacg
    10621 cgtagccatt ctcctcctgg tctttgttga cccctgtgcc gctggtccac acctgaatga
    10681 tgttattggt atacggcgac agtttgtcgt tgttcgacca ggtctgttcc ccttgcgggt
    10741 tacgttcagg ggagttgata tcctgacact tggtgacgca agcctgacag cctacgcaca
    10801 aggtcgagtc gtacaacatc cccagcgatc ccggaattgg cgggcggttt tcagcagccg
    10861 catgactgac agacggcagc gcgcccgtca gcaatgcccc gcaggaggct gctttaataa
    10921 aattacgtct gttcacggtt attctccccg tgagtcagcg ttatctttct tttgctgacg
    10981 acccagttca cgcaccgcca tcacgctgac accggcaacc agcccaacca ctccgccgag
    11041 caaaccaata gcgcctgccg agacgttgcc gccttcttta gcgttaacgt ccggtttctg
    11101 tgaacgcgga gtctggtttt cgacgttggc aagctgatgg atgcctttat ggaagccgat
    11161 accttcttcg ttacagccat agcacgggtg accaatcgct accggccaca cgccgccaac
    11221 atcgcagaat tgcagcgttg agcagttgcc gtaagtttct ggccctttac agccgaggtg
    11281 gtacaggcac cagccttcgc ggtggccttc atcaccgaac tctttggcaa aacgaccagc
    11341 atcgaagtgc gggcgacgtt cacagtgttc gtgaatcaga cgaccatagg cgaaagtcgg
    11401 acggtttttg tcatccagtt tcggcggttt gccgtaagtg atgatgtgcg caacggtcgc
    11461 caggaagttg tgcgggttcg gcgggcagcc aggaatattg ataacggttt tgcccggtag
    11521 aacttcttgc aggctgactg cgccagttgg gttaactcca gctgcggcaa caccgcccca
    11581 cgcagagcag gaaccgatag cgataatggc tgctgcgcct tccgccgctt tgcggatgtg
    11641 atccacaatc ggctcaccgg caaccatgca ataaataccg ttatctttta atgggatgga
    11701 accatccacc actaacacat actgcccttt gtacttctcg agagcgttat gtttgttctc
    11761 ttcgacctga tgaccgaagg cggcggaaag cacttcgtga tactccagag agatagtctc
    11821 cagcacgagg ttttctaccg ttggatgcgt tgcacgaagc agagattccg tacaaccggt
    11881 gcactcctgc gcgccaatcc agataactgg cggacgctgc gggttagtaa ccgattcgac
    11941 catctctgca gcggctttgc tacttaaccc catggtggcg gctaatgctg cacaaagctt
    12001 catgaaatca cgacggttaa tgccgtgaga atggatgagg gtgttatctc cagtcattta
    12061 tagttattcc gttgcgaaga cctggcatat attttgcctc aatcgcaaaa tcaataatgc
    12121 gatcgatgcg ccatttacca cacatttatt atggttatcg atatcatgat actgcggcgg
    12181 ggcactaaaa cgaagggaag aagcattagt gtaattaatt aaagcaagat aatacgtatg
    12241 tttgatcaat tttctaggcg ataaccggcc ataaaaaagc gcaacgtaga acaggaatta
    12301 ttctcacgaa agaaatccat taccatctct ttatccagtc cataacggcg cgtcagaata
    12361 cccgcttccc aggcgctaag ctggcgatct ccggtctttt cgtacatccg gtgtgagtag
    12421 cctaatacaa aaccgcgttt ataatcggca cagaattttg tcacattaac cgcactgtcg
    12481 gcatgcgttg cttttaatcc cgccattaag cctttaccaa aatggttatt catcgttcac
    12541 ctcattcgct atatattgtc atatatagcg atattttagg caaagaacga catttgcgca
    12601 cgctattttt tcatgcttgt ttaagacgta atcctgtaag agataaaccc atcaggagag
    12661 atatttatcg aaccatttca gcgtcctttg ccaggcaaga tcggcggcag atttgtcata
    12721 acggggcgtg gaatcattat ggaatccgtg attaaccccc ggatatatat acgcctcata
    12781 gaccttatta ttggctttca acgccgcctc gtaagcgggc cagccctcgt tgattcggct
    12841 atccagttca gcgtagtgga gcagtaaagg cgcttcaatc ttcgccacat cggcagtggg
    12901 tgcctgacgc ccataaaacg gcaccgcgca ggccagttcc ggatacgcga ctgctgccgc
    12961 gttcgatacg cccccgccat agcaaaatcc gctaataccc actttgcctg tcgcttgcgg
    13021 atagcgttgc ataaactcaa ttgcggcaaa gaaatcattc atcagtttgg ttggatcaac
    13081 ctgctgttgc agttcgcggc ctttatcatc gttaccagga tagccaccta ctgagcttaa
    13141 accgtctggc gccagggcga tgtacccagc cttcgccact cgccgcgtca catcttcgat
    13201 atacggattc agccctcgat tctcatgcac cactaccacg gctggcgttt tgccgctcat
    13261 ttttgcgggc ttcaccagat aaccccgtac ctcgccgtga ccatttggcg agggatacgt
    13321 gatgtactca gcaacaattt ccgggtcggt aaactctacc tgagtcgcca acgcataatt
    13381 tgacttgagc aaatcaaaca gcgctaatgc cgtcatcccg cccaccgcat acttcgccgc
    13441 aaggttgagg aactcacgtt tcgagatttt cccgtgagcg taatagtcgt agtaatccag
    13501 caactcttgt gggaaatctt tggcggttaa acgcggcatc gttgcactcc tcaactggtg
    13561 tttttttaag caaagcataa gcgcgtgttt ttgcccagtt tttcgtcact ctgtgagcca
    13621 gactacggga tacgcgctgg cgaatcgcta aactagaaac attgtttcga aattgaacga
    13681 tggaaaggag aggtcatggt ctggttagcg aatcccgaac gttacgggca gatgcagtac
    13741 cgctattgcg gaaaaagtgg tttacgcctg cccgcgttat cgctcggttt atggcacaat
    13801 ttcggtcacg ttaacgcgct ggaatcacag cgtgcgatcc tgcgtaaagc gtttgattta
    13861 ggcattacgc actttgattt agccaacaac tacgggccgc ctccaggaag cgcagaagag
    13921 aactttggtc gcctgctgcg cgaggatttt gccgcttatc gcgatgaact gattatctct
    13981 accaaagccg gatacgatat gtggcccggc ccatacggct ctggcggctc acgtaaatac
    14041 ctgctcgcca gcctcgacca aagcctgaag cgtatggggc ttgagtatgt cgatatcttt
    14101 tactctcatc gcgtcgatga aaatacgccg atggaagaaa ccgcctctgc gctggctcat
    14161 gctgtacaaa gcggtaaggc gctgtatgtc gggatctcct cttactcgcc agagcggacg
    14221 caaaaaatgg tcgagttgct gcgcgagtgg aaaattccgc tgttaattca tcaaccttcg
    14281 tacaatttac tgaaccgctg ggtggataaa agcggcctgc tggataccct gcaaaataac
    14341 ggcgtgggct gcattgcctt tactccactg gcacagggat tgctgaccgg aaaatatctc
    14401 aacggtattc cgcaagattc acggatgcat cgtgaaggga ataaagttcg tggtctgacg
    14461 ccgaaaatgc tcaccgaagc caacctcaac agcctgcggt tattgaatga aatggcacag
    14521 cagcgtggac aatcaatggc gcaaatggcg ttaagctggt tgctgaaaga tgatcgcgtg
    14581 acgtcggtat tgattggtgc cagccgcgcg gagcaacttg aggagaacgt gcaggcgctg
    14641 aataatctga catttagcac cgaggagctg gcgcagattg atcagcatat cgccgatgga
    14701 gagctgaatt tgtggcaggc gtcttccgat aaatgacctg ttaataacgg gcgcgagaac
    14761 cgcgcccgaa tcagatcagt gattatgacg agtcagtcgg tcaagatagc ccatcacaaa
    14821 tgcagagagc acaaacgtca gatggataat gacgtaccac atcagtttgt tatccgggac
    14881 atttttcgca tccataaaga cgcgcagtaa gtgaatggaa gaaattgcca caatcgacgc
    14941 tgctactttg tttttcagcg acgttgcatc cattttcccc agccagttca gcttctcttt
    15001 gttctcggag atatccagtt gtgagacgaa attctcgtaa ccggaaaaca tcaccatcac
    15061 cagcaaaccg ccaaccagcg tcatatccac cagcgacagc aacacgagga tcaaatctga
    15121 ttccgccatc gagaagatat tcggcagtac gtgaataatc tcctggaaga acttcagcgc
    15181 cagggcaact aacgccagcg aaaggccaaa gtacacgggg gcaagcagcc agcgagaagc
    15241 atacattgca ttttcaagaa aacgttccat acattcctgt cgtgtagtta aaacgggcaa
    15301 cagtatatcg caattaagta aacagcacgc aacagcaaat caacatatac gttaaacctt
    15361 tgtcgcataa ttctgagggt tagggatctt cctggttccc ttatcaacgc atcgagagcg
    15421 tctaccctta aaggacgttg aacctgaagg gagaaaaacg atgtctcatt taaaagaccc
    15481 gaccacgcag tattacactg gtgaatatcc caaacagaaa caaccgacgc caggcatcca
    15541 ggcgaagatg acaccggtac cggattgcgg cgagaaaacc tatgttggta gcggtcgcct
    15601 gaaagatcgt aaagcactgg tgacaggggg cgattccgga atcggtcgcg ctgccgccat
    15661 tgcttacgcg cgtgaagggg ctgacgtggc gatcagttat cttcccgtgg aagaagaaga
    15721 cgctcaggat gtgaaaaaga tcattgaaga atgcggacgc aaagccgttc tgctgccagg
    15781 cgatttaagc gatgagaaat tcgcccgttc gctggttcac gaagcacaca aggcgttagg
    15841 cgggctggat attatggcgc tggtagccgg gaaacaggtt gccattcctg atattgcaga
    15901 cctcaccagc gaacagtttc aaaagacctt tgccattaac gttttcgcgt tgttctggct
    15961 aacccaggaa gcgatccccc tgctaccgaa aggtgcaagt atcatcacca cttcctcaat
    16021 ccaggcatac cagccaagcc cgcatttact ggactatgcg gctacgaagg cggcaattct
    16081 gaactacagc cgtggcctgg caaaacaggt cgcggagaaa ggtattcggg tgaatattgt
    16141 cgcgccaggc ccgatctgga cagcactgca aatttctggc ggacaaacgc aggataagat
    16201 cccgcagttt ggtcagaaaa cgccgatgaa gcgtgcgggg caaccggcgg agctggcccc
    16261 tgtatatgtt tacctggcaa gtcaggagtc gagctacgtc accgcagaag tgcacggtgt
    16321 ctgcggcggc gagcatttag gttaaaaaaa tgcccggttg tgaaaagcaa ccgggcatca
    16381 tttttatttc gctttcgcag tttcttcgcc gaccagacct attttcaggt aacccgcctg
    16441 atgcagcgta tccattacct tcatcaacgt ctcgtaatcg acagttttat ccgcacggaa
    16501 gaagatggtg gtgtctttct tgccttcggt taacgcattc aacgccgtaa tcattgtttc
    16561 atcggtgacc ggatcgttac caataaacat cgagttgtct gctttcaccg acagataaac
    16621 cggtttttcc gggcgcggct gcggcgtgct ggtagaagca ggcaaattca ccttcacatc
    16681 taccgtcgct aacggtgccg ccaccataaa gataatcagc aaaaccaaca tcacgtcgat
    16741 aaacggcgtc acgttgatat catgcatttc gccgttatcg tcgaggtttt cgttaagatg
    16801 catcgccatc ggacattatc ctgcacgtaa tttttgtgcg acacgaaccg gatgcgcagc
    16861 ggcgctggct tccagatcca ggtcacggct ttgcagcaac aatacctgcg ctgcaacatc
    16921 acccagcatc gctttaaagc cgccaatctg gcgtgcaaat acgttataga taacgaccgc
    16981 aggaatcgct gccacgaggc cgattgccgt tgctaacaga gcttctgcaa tacccggcgc
    17041 aacgactgcc aggttagtgg tctgcgtttg cgcgatacca ataaagctgt tcatgatgcc
    17101 ccagaccgta ccaaacagac caacgaacgg cgaaatcgcg ccgatggttg ccagatagcc
    17161 gttaccacgg cccatttgac gacctactgc ggcgacccga cgctccagac ggaagctggt
    17221 acgttcttta ataccttcgt tatcgtcgct gccttctgac agttccagct cattctgcgc
    17281 ttcattgagc aaatgcaggc tcaagctttt gctaccaaaa tcagcggcga tatcgttggc
    17341 ctggtttaag gaacgcgctt cagccagcag ttgctgctcg cgcttaagac gacgcttctg
    17401 attgaagaac tccacgctct tactgaagaa gattgcccag gtgactacgg aggccaaaat
    17461 aagcccaatc atcacgcact taacgacaat atcggcgtgc tgatacatac cccagacgga
    17521 gaggtccgtc tgcattaaat tattacccac tgtgtatctc caggacgcaa gtcacaaaat
    17581 ctgtgcataa taatatcaaa acgacgtcga attgatagtc gttctcatta ctatttgcat
    17641 actgccgtac ctttgctttc ttttccttgc gtttacgcag taaaaaagta accagcacgc
    17701 catttgcgaa aattttctgc tttatgccaa ttcttcagga tgcgcccgcg aatattcatg
    17761 ctagtttaga catccagacg tataaaaaca ggaatcccga catggcggac aaaaagcttg
    17821 atactcaact ggtgaatgca ggacgcagca aaaaatacac gctcggtgcg gtaaatagcg
    17881 tgattcagcg cgcgtcttcg ctggtctttg acagtgtaga agccaaaaaa cacgcgacac
    17941 gtaatcgcgc caatggcgag ttgttctatg gacggcgtgg aacgttaacc catttctcct
    18001 tacaacaagc gatgtgtgaa ctggaaggtg gcgcaggctg tgtgctattt ccctgcgggg
    18061 cggcagcggt tgctaattcc attcttgctt ttgtcgaaca gggcgatcat gtgttgatga
    18121 ccaacaccgc ctatgaaccg agtcaggatt tctgtagcaa aatcctcagc aaactgggcg
    18181 taacgacatc gtggtttgat ccgctgattg gtgccgatat cgttaagcat ctgcagccaa
    18241 acactaaaat cgtgtttctg gaatcgccag gttccatcac catggaagtc cacgatgttc
    18301 cggcgattgt tgccgccgta cgcagtgtgg tcccggatgc catcattatg atcgacaaca
    18361 cctgggcagc cggtgtgctg tttaaggcgc tggattttgg catcgatgtt tctattcagg
    18421 ccgccaccaa atatctggtt gggcattcag atgcgatgat tggcactgcg gtgtgcaatg
    18481 cccgttgctg ggagcagctg cgagagaatg cctatctgat gggccagatg gtcgatgccg
    18541 ataccgccta tataaccagc cgtggcctgc gcacattagg tgtgcgtttg cgccaacatc
    18601 atgaaagcag tctgaaagtg gctgaatggc tggcagaaca tccccaagta gcgcgagtta
    18661 accaccctgc tctgcctggc agtaaaggcc acgaattctg gaaacgagac tttacaggca
    18721 gcagcgggct attttccttt gtgcttaaga aaaaactcaa tgatgaagag ctggcgaact
    18781 atctggataa cttcagttta ttcagcatgg cctactcgtg gggcgggtat gaatcgttga
    18841 tcctggcaaa tcaaccagaa catatcgccg ccattcgccc acaaggcaag atcgatttta
    18901 gcgggacctt gattcgcctg catattggtc tggaagatgt cgacgatctg attgccgatc
    18961 tggacgccgg ttttgcgcga attgtataac attgccactt ttggacaatt ttgcagacat
    19021 tttattgtga aaagtcttaa attgttgcgt ccgggatcaa ggcgtcccgg acgattcagg
    19081 agtacaatag gcagataaag gcttaaacgc tgttccacag gaaagtccat ggctgttatt
    19141 caagatatca tcgctgcgct ctggcaacac gactttgccg cgctggcgga ccctcatatt
    19201 gttagcgttg tttactttgt tatgtttgcc acgctgtttt tagaaaacgg cttgctgccc
    19261 gcctcatttt tgccaggcga cagcttgttg atactggcag gcgcattgat tgcccagggg
    19321 gttatggatt ttctgcctac gattgcgatt ctgaccgccg cagcaagtct gggctgctgg
    19381 ctaagttata ttcaggggcg ctggttaggg aataccaaaa cggtgaaagg ctggctggca
    19441 cagcttcctg ctaaatatca ccagcgcgcc acctgcatgt ttgaccgcca cggtctgctg
    19501 gcgctgctgg ctggacgttt tcttgcattt gtccgtacgc tgctgccaac catggcggga
    19561 atttccggtc tgccaaaccg ccgcttccag tttttcaact ggttaagcgg attgctgtgg
    19621 gtcagcgtgg taaccagttt cggctatgcc ttaagtatga ttccgttcgt taaacgacat
    19681 gaagatcagg taatgacgtt cctgatgatc ctgccaattg ccttgttaac cgctggcttg
    19741 ttgggcacgc tgtttgtggt gattaaaaaa aaatactgta acgcctgacg attttccccg
    19801 ttcccggttg ctgtaccggg aacgtattta attcccctgc atcgcccgca ttcttgccgc
    19861 atcttccccc ggcgtcacac cgaagtaacg tttaaactca cggctaaatt gcgatgcgct
    19921 ttcatagccg acgcgcatcg ccgccgcgct ggccttcatg ccgtcgtgga tgatcatcat
    19981 ccgcgcctta tgcagacggt aattcttcaa atactgcaac ggcgaggtgc tggtgacaga
    20041 cttaaaatta tggtggaacg ccgatacgct catgttggct tctgccgcca gttgctcgac
    20101 gctcaggttt tcggtgtatt tattctcaat ccgtttcagc acgcgactaa tcaggctgaa
    20161 gtgagtctgg cggctgacca gtgccagtaa cgcgccgccg caaggtccgg tcagcacgta
    20221 gtacagaatt tcgcggatga tctgtttgcc gagaatacgc gcatccagcg gtcgctccat
    20281 cacgtcgagt aaccgctccg ccacgcataa aatctcttct gataacgtgg cagagttaat
    20341 cccgctggct gccatcgacg gctggaaatg ctcatcttcg ccaatgtcca tcaacagttc
    20401 ctgtaactgc aaaatatcga cattgagacg caaccctgcc agcggcacct ctgacgtggc
    20461 ataggtttcg cactcaaacg gcaacggcac cgtcagcagc aggtattcat tggcatcata
    20521 acgaaacacg cgttcattga tataaccgat tttatgcccg gaaaagagaa ttatgatgcc
    20581 aggctcgtac atcaccggtg tgcgtgcgaa aggcgtctcg ccatacaaca aacgcacatc
    20641 gggcaacagc tctgacaaac tattttcttt atttttcagt ttattaactt tatccgccag
    20701 caagcggcaa atctcttcac gtttcatatc gcgtaatttc ttaggaataa tgcggcaatt
    20761 tgattgtgcg caattttgta gcatttctcc agcactctgg agaaataggc aagacattgg
    20821 cagaaatgag cattgagagg tacggcgctg gcgaccacaa tgaaaaacat caggcagacc
    20881 gatctctgcc ctcatattga cccagcaaag ggagcaagta atgaacaact ttaatctgca
    20941 caccccaacc cgcattctgt ttggtaaagg cgcaatcgct ggtttacgcg aacaaattcc
    21001 tcacgatgct cgcgtattga ttacctacgg cggcggcagc gtgaaaaaaa ccggcgttct
    21061 cgatcaagtt ctggatgccc tgaaaggcat ggacgtactg gaatttggcg gtattgaacc
    21121 aaacccggct tatgaaacgc tgatgaacgc cgtgaaactg gttcgcgaac agaaagtgac
    21181 gttcctgctg gcggttggcg gcggttctgt actggacggc accaaattta tcgccgcagc
    21241 ggctaactat ccggaaaata tcgatccgtg gcacattctg caaacgggcg gtaaagagat
    21301 taaaagcgcc atcccgatgg gctgtgtgct gacgctgcca gcaaccggtt cagaatccaa
    21361 cgcaggcgcg gtgatctccc gtaaaaccac aggcgacaag caggcgttcc attctgccca
    21421 tgttcagccc gtatttgccg tgctcgatcc ggtttatacc tacaccctgc cgccgcgtca
    21481 ggtggctaac ggcgtagtgg acgcctttgt acacaccgtg gaacagtatg ttaccaaacc
    21541 ggttgatgcc aaaattcagg accgtttcgc agaaggcatt ttgctgacgc tgatcgaaga
    21601 tggtccgaaa gccctgaaag agccagaaaa ctacgatgtg cgcgccaacg tcatgtgggc
    21661 ggcgactcag gcgctgaacg gtttgatcgg cgctggcgta ccgcaggact gggcaacgca
    21721 tatgctgggc cacgaactga ctgcgatgca cggtctggat cacgcgcaaa cactggctat
    21781 cgtcctgcct gcactgtgga atgaaaaacg cgataccaag cgcgctaagc tgctgcaata
    21841 tgctgaacgc gtctggaaca tcactgaagg ttcagacgat gagcgtattg acgccgcgat
    21901 tgccgcaacc cgcaatttct ttgagcaatt aggcgtgctg acccacctct ccgactacgg
    21961 tctggacggc agctccatcc cggctttgct gaaaaaactg gaagagcacg gcatgaccca
    22021 actgggcgaa aatcatgaca ttacgctgga tgtcagccgc cgtatatacg aagccgcccg
    22081 ctaagctttt tacgcctcaa actttcgttt tcgggcattt cgtccagact taagttcaca
    22141 acacctcacc ggagcctgct ccggtgagtt catataaagg aggaacgtat ggctaatcca
    22201 accgttatta agctacagga tggcaatgtc atgccccagc tgggactggg cgtctggcaa
    22261 gcaagtaatg aggaagtaat caccgccatt caaaaagcgt tagaagtggg ttatcgctcg
    22321 attgataccg ccgcggccta caagaacgaa gaaggtgtcg gcaaagccct gaaaaatgcc
    22381 tcagtcaaca gagaagaact gttcatcacc actaagctgt ggaacgacga ccacaagcgc
    22441 ccccgcgaag ccctgctcga cagcctgaaa aaactccagc ttgattatat cgacctctat
    22501 ttaatgcact ggcccgttcc cgctatcgac cattatgtca aagcatggaa aggcatgatc
    22561 gaattgcaaa aagagggatt aatcaaaagc atcggcgtgt gcaacttcca gatccatcac
    22621 ctgcaacgcc tgattgatga aactggcgtg acgcctgtga taaaccagat cgaacttcac
    22681 ccgctgatgc aacaacgcca gctacatgcc tggaacgcga cacacaaaat ccagaccgaa
    22741 tcctggagcc cattagcgca aggagggaaa ggcgttttcg atcagaaagt cattcgcgat
    22801 ctggcagata aatacggcaa aacccctgcg cagattgtta tccgctggca tctggatagc
    22861 ggcctggtgg tgatcccaaa atcggtcaca ccttcacgca ttgtcgaaaa ctttgatgtc
    22921 tgggatttcc gtctcgacaa agacgaactt ggcgaaattg caaaactcga tcagggcaag
    22981 cgtctcggtc ccgatcctga ccagttcggc ggctaacgtg caaattctcc cggtggcggt
    23041 aatgttccgc taccggactt ttcagaaatc atttattccc ctcgcgtccc gcccgttgct
    23101 actcttcctt gttcaggaat gccaaatata aggacatcat catgcagagc cggaagctct
    23161 taaaagaaca actcatctat atccgggata aacgcaacgg agaggtgaaa aacagatgaa
    23221 aataatactt ctgtttttag cagccctggc aagttttacc gtacacgcac agcccccctc
    23281 acagaccgta gaacaaacag tccggcatat ttatcagaac tataaatcag atgccactgc
    23341 cccttatttt ggtgaaaccg gagagcgagc gataacttct gcgcgtattc aacaggcgct
    23401 taccctgaac gacaatctta cgctgccggg caatattggc tggctggatt atgatccggt
    23461 ttgtgattgt caggattttg gcgatctggt gttagaaagc gtagcgataa cccaaactga
    23521 cgccgatcat gccgatgcca ttgtgcgctt tcgtatcttt caagacgata aagaaaagac
    23581 ctcgcagaca ctgaaaatgg tggcggaaaa tggtcgttgg gtcattgacg atattgtcag
    23641 caatcatggc agcgtcttac aagcggttaa tagcgagaat gaaaaaacac tggccgctat
    23701 agcttcgttg caaaaagaac agccggaagc ctttgttgcc gaactctttg aacatattgc
    23761 tgattatagc tggccgtgga cgtgggtggt ttccgactct taccgccagg cggtcaatgc
    23821 cttctataaa accaccttca agacggccaa caatcccgat gaagatatgc caatagaacg
    23881 gcaatttatt tacgacaatc cgatctgttt tggcgaagag tcgttatttt cacgcgttga
    23941 tgaaattcga gtcctggaga aaaccaccga ttccgcccgc attcatgttc gctttacgct
    24001 gaccaatggc aacaacgaag agcaagaact gattttacag cggcgcgaag gtaagtggga
    24061 aatcgctgat tttatccgcc cgaacagcgg cagcctactt aagcagattg aggcaaaaac
    24121 cgccgccaga ttaaaacaat gagctgaatt aaataacaat tagccggaac aataaataaa
    24181 agggaacact atatgaaaac gattttcacc gtgggagctg ttgttctggc aacctgcttg
    24241 ctcagtggct gcgtcaatga gcaaaagatc aatcagctgg cgagcaatgt gcaaacatta
    24301 aatgccaaaa tcgcccggct tgagcaggat atgaaagcat tacgcccaca aatctatgct
    24361 gccaaatccg aagctaacag agccaatacg cgtcttgatg cacaggacta tttcgactgc
    24421 ctgcgctgct tgcgtatgta cgcagaatga taaaaaaatc cccggcagca ttctgttacc
    24481 ggggatattt tttaacgtcc aaccgccgct ttagggcgtt tcttcgcacc agcattctgc
    24541 aggcgagatt gcgtagacga cgcttttttt gccgtagcag gcgtctgacg ctgggtcgcc
    24601 atcggcgtat gtttagtcaa cgccggacgg gtattgcggt tctggcgacg agcctcacgc
    24661 atctcttcaa tagttggcgc aggcactaag caatcgcgac ggctgccaat cagatgcttt
    24721 ttgcccatcg cttccagcgc ctggcggatt aacggccagt ttgccggatc gtggtaacgc
    24781 aacaacgctt tatgcaaacg acgctgtttg tcgcccttcg gcacgaagac gtcttcactc
    24841 ttataaccaa tcttcgccag cgggtttttg ccggtgtaat acatggtggt cgagttagcc
    24901 agcggcgacg gatagaagtt ctgcacctgg tcgaggcgga agcgatgctt tttcagccat
    24961 agcgccagat tcaccatatc ttcatcacgc gtacccgggt gcgcggagat gaaatacggg
    25021 atcagatact gttctttacc tgcctgtttc gagtaagtat cgaacagctc tttaaagcgg
    25081 tcatagctgc ccatgcccgg cttcatcatc ttcgataacg gcccttcttc ggtatgttcc
    25141 ggggcaatct tcagataacc gccaacgtga tgggtcgcca gctctttgat atagcgcgga
    25201 tcttctacag cgatgtcata acgcacacca gaggcaatca ggatcttttt aatgcctttc
    25261 agatcacgcg cacggcgata gagattgatg gtcggttcat gattagtgtc catgtgcgaa
    25321 caaatatccg gataaacgca cgacaaacga cggcaggttt gctcagcgcg tggcgatttg
    25381 cagcgcaaca tatacatgtt ggcagtaggc ccaccgagat cggaaatcac gcccgtaaaa
    25441 cctggaacag tgtcgcggat cgcttcgatc tcattaataa tcgaatcttc ggaacggctc
    25501 tgaataatgc gcccttcgtg ctcggtaata gaacagaaag agcagccgcc aaagcagcca
    25561 cgcataatgt tgaccgagaa acgaatcatt tcgtaagccg gaattcgggc attaccgtaa
    25621 gccggatgcg gcacgcgctt gtacggcagc gcaaagacgc tatccatctc ttcggtagaa
    25681 agcggaatag caggcgggtt gatccataca tagcggtcgc catgtttttg catcaatgcg
    25741 cgggcgcagc ctgggttagt ttcgtggtgc agaatgcgcg aagcatgggc gtacagcact
    25801 ttatcgccct tcactttctc gaaagaaggc agcaacacgt aggttttttc ccacggtttc
    25861 gggcgtggtg gctgcacggt tacagatttg gcttcctgct ttttcggagc taccggtttg
    25921 ttatccgcgc acggcaaatc ttcgccatac ggatgcggga ttgggtcgat tttcccaggg
    25981 gtatcaagac gggtggaatc cacaccgctc cagcctggca acgcctcttt tacgataatc
    26041 gcggtattac gcacatcgcg gatttcacta atcggctcgc ccatcgccag acggtgcgcc
    26101 acttccacca gcggacgctc accgttacca aacatcagca tgtcggcttt cgaatccacc
    26161 agcacggaac ggcgcacggt atccgaccag taatcatagt gcgcggtacg gcgcaggctg
    26221 gcctcaatac cgccgaggat caccggcaca tctttccacg cctctttaca acgttgggta
    26281 taaaccagtg tggcgcgatc cggacgctta cccgcgacat tatctggcgt gtaggcatcg
    26341 tcatgacgta aacggcgatc ggcggtatag cggttgatca tcgagtccat gttgccagca
    26401 gtaacaccga aaaacagatt cggtttaccc agacgcataa agtcgtcttt actgctccag
    26461 tctggctggg cgatgatccc gacgcgaaag ccctgcgctt ccagcatacg accgcaaatc
    26521 gccatcccga agcttgggtg atcgacatac gcgtcgccag taaccaaaat gatgtcgcag
    26581 ctatcccagc ctagttgatc catctcttca cgtgacatcg gcaaaaacgg tgccggtcca
    26641 aaacaggcgg cccagtactg cggccaggag aacaggtcgc gatccggttg gatcagggag
    26701 atagagctca ttttgcttcc agaaatggta aaaaaataat caaaggccgg ggattatacg
    26761 ctgtatcacg cgcggaaatg aagtgatgtt gatgaacggt ggcgaaatac cctggtgagg
    26821 tttttcactg cccgacttgg gcaagcacat ttaaggctgg cggtatcgtg gcaactgccg
    26881 ctactattta tgccgctcag caacgttcaa atcatattgc acgtcgatcg gctatccgag
    26941 gacacccaca gtaaggcaag gtatggaaca ggttattaca aagcgccgct attacgatat
    27001 tggtctacag attgaagagc tgctgtattc aggcgtattt aaggccggag aacgcttacc
    27061 ttcagaacgt gaactgagcg agcggtttaa taccagccga actaccattc gtgaagccat
    27121 cattatgctg gaactgaaag gcgtattgaa tgtgaagcaa gggtcaggga ttttctttgt
    27181 cgactccacc gataagctca accagaaatc attaatgccc tattcagaaa ttggcccgtt
    27241 tgaactgtta caggcacgtc aggtaattga gagcaatatt accggttttg ctgccagcca
    27301 gatcagcttt aacgagttac aagagttgaa gaaaatcatt ggattacagg aaaaagccat
    27361 cgctgcggaa agtgataaat ttgaagacct ggatcaccga tttcatagca ttattgccga
    27421 agcgacgcaa aatcgggtac tcatcaaaca agctgctgaa ttatggcggg cagttcgtac
    27481 agaaaacccc cgctggaaga aacttaacta caagtacctg catgaaaagc atttgcgtct
    27541 gcaatggctg gaagatcacc gggctatttt cctggctctg caacagaaag attcagagct
    27601 cgccagggaa gcgtcctgga gacatctgga aaacagcaaa aatgaactga tcaaaatctt
    27661 caaacaagac gcttccatca gcgattttga tgactttttc ttcgctcgtt aaccttcatt
    27721 agtccagagc tggcggaaaa aataacgccg gctctgcctt ccgccctcca ctggtacacg
    27781 ctctcttttt aattggtcta ataaatcgac tatcatcaga tatcttagat tagcggcaat
    27841 tatcctaaaa actgacctct aaaaaacttt cctttcattt tattcatata actcattgat
    27901 acagatataa ataacgcctt gttgttctgt ttcgtacttt tacctttctc tgcaagcgtg
    27961 atgcatctct ctgtttttgg tctaatgaat tatgtaaatt ggtatacaca caagccacca
    28021 ggagtaagag cataatgtca gggaacgaaa gtatcgatgc cgcccactat gatcaggtaa
    28081 ccacctggcc tcggggcggg ttacaggcag atattgtcca tattggtttt ggcgcttttc
    28141 atcgcggaca ccaggctgtc tacacggatc tcactaatca gctttctgac acccactggg
    28201 ggatctttga gatcaacctg tttggtgatg ctcaactgat cgaaaactta aatgcgcaaa
    28261 atgggctgtt ttcggttgtg gaaacatctg catcgcaatc tacctcacgc cttgtgcgtt
    28321 cggtaactgg cggtattcat acccccgtgg atggcattgc cgcagcaatc cagaaattga
    28381 ctgaacctca ggtaaaaatc gtttcattaa ccatcaccga gaaaggctat tgtctcgatt
    28441 cgcaaacgcg atcgcttgat ctcaccaatg gattaatcaa acacgatcta caaaacccgg
    28501 atgcgcctca gtcggctatt ggcttgatcg tctgtgcttt gcaacaacgt aaagcggcag
    28561 ggctcgccgc ttttagcgtg ctctcctgcg acaacttgcc agacaatggg catctgacgc
    28621 gaaatgccgt tctcggtttt gcccgacaac tggaccagcc cctggctcag tggatcgaag
    28681 aaaatgtctc atttccaggc acgatggtcg atcgcattgt tccggcaatg accgaatcgc
    28741 aattcgcctt actggaaact aaaaccggtt atgccgatcc ctgcgggatc gtctgcgaat
    28801 catttcgtca gtgggtgatt gaagataatt ttgtgcatgg gcgaccacaa tgggataaag
    28861 caggcgcgat gtttgtcagc aatgttcagc cttatgaaga gatgaagtta cgcatgttaa
    28921 acggtggcca ttcatttctg gcctataacg gctcactggc tggctatgaa tttatctggc
    28981 aatgcatgga agacgctgat tttcgttcca ttacccgcca actgatgatt aatgaacaag
    29041 cccgaacact taatccagac ttaaatatcg acgcccagga atacgccgac ctgttaattg
    29101 aacgctttag caaccgtaat gttgcacacc gtaccgggca aatcgctatg gacggttcac
    29161 aaaagcttcc ccagcgtgcg ctgacgccct ggctgaaatt gcatcagcaa aaacaaaaca
    29221 atgctgttct gtcactgctc gttgctggtt ggttgcatta tgtcattgaa gctgttgaga
    29281 aaagccagtc tgtcgcggat ccaatgaatg aacaatttca ggcgctaata aaggaacaac
    29341 aagacgcatg gcaacaggcg ctcgcattac tgcaccttag cgccatattt ggtgatttaa
    29401 gcaaccatca gccatttata aatgaaataa aaatcgcctt tgcaaatata aaaaacaaag
    29461 gcatcaaggc caccatcagc caattattat cggatgagca gaaatgaaaa cattaatttg
    29521 tcagcagcct ggcgttatgg aatatgtgga aaaggatatt cccacaccag cagataatga
    29581 agtgctgtta aaaataaaag ctgtgggtat ttgtggtact gatattcacg cttttgccgg
    29641 cagacagcct ttttttagct acccacgtgt attaggtcat gaaatatgcg ccgaagcggt
    29701 ttcgcgaggc agccagtgcc aaacagcaca atcaggccag cgctattccg tcatcccatg
    29761 cattccgtgt ggcgagtgcg cagcctgtcg ggaagagaaa acgaactgct gcgaacgtgt
    29821 ttcgctgtat ggcgtgcatc aggatggggg ttttagtgag taccttgcgg tacgtgaaga
    29881 caaccttgtg cctctccctg acgaggtcag cgacagtgcc ggagcattgg ttgaatgttt
    29941 cgccattggt gcacatgccg ttcgtcgggc agagatcaag gctgaacaaa acgtactggt
    30001 gattggcgct gggccaatcg gtctggctac cgcagccatc gcccgggcta aaggggcaca
    30061 tgttgttgtt gctgatattg actgtcaacg tcgccagcac gttgtggatc atctggcgat
    30121 taatgccttc aatcccacac aggaagattt tattgccgcg cttcgtgagg cctttggagg
    30181 cgaactggct tgcgtagtac tggatgcgac gggaaataaa gcttcaatga gtcatgatgt
    30241 caatcttatt cgtcatggcg gcaaaattgt tttcatcggt ttgtacattg gtgaacttgt
    30301 tattgacgat ccgaccttcc ataaaaaaga gacaacgtta ctcagcagcc gcaatgccac
    30361 acgggaagat tttgcgttgg tgattgaact gatgcgcagc aataaaattc acgaaaattt
    30421 aatgaaaaac caggcgttca atttctttag tgttggcgaa gattaccagc gtaacgttgt
    30481 agaaaataaa aatatggtca agggtgtgat cactttttaa gggaacaaat atgacaactg
    30541 tttatgtcag tgaagaaaat ttaaaatcac tggtgcacca caaattacat accgccgggc
    30601 tggataccga caccacacaa caggtgacag atgttttagt acatgccgat attaccggtg
    30661 tgcattcaca tggtgttatg cgtgtcgaac attattgcac ccgccttgct gccggagggt
    30721 taaataaagc cccgcagttt agcattgagc aaatttcacc gtcagtggcc attctcgact
    30781 ctgacgacgg aatggggcat tccgcattaa ttagcgccac tgagcacgct attaaactgg
    30841 cccagcaaga gggtctcggt tttgttagcg ttaaaaacac gtctcactgt ggtgcgttat
    30901 cttattttgc agagatgatc accaacaaag ggttggttgc tatcgtaatg acgcaaaccg
    30961 atacctgtgt ggctccccat ggcggcgccg agcgcttttt gggaactaac cccatcgcct
    31021 ttggtttccc ggtggaaaac agccatccga tgattgttga tatggcgacc agtgccacgg
    31081 ctttcggcaa aatacttcat gcaaaggaaa ccggaaaaca tattggtgaa ggactggcga
    31141 tagataaaaa cggttatggc accactgatc cgtataagat tgaaaacctg ctacctttcg
    31201 gccaacacaa aggttcaggc attgcactgg ctattgatgc actgactggc gtgctgatga
    31261 atgcgaattt tggcaaccat attgttcgca tgtatggtga ttatgacaag atgcgtaagc
    31321 tggcaagttt ggttattgcc atcgatccga aaaagctcgg caatcctgtt tttgcaaaaa
    31381 ctatggcgaa aatggtcacg gagctgcatg ccgttaaacc ggctcctggt gtcgaaaaag
    31441 tgttagcgcc gaacgatccg caaatgcact acaaagaaaa atgccaacag gaaggtattc
    31501 cggttccggc aggaatattc cattatctgg cagagaatta atcactattt tttattataa
    31561 cgatagaaaa gcgctgtatt tatcgtttct gttatattaa ccaggagcag gatatgaaag
    31621 cacttcgtcc tctgacggca tcgcttatgc tgttaaccag ttgtttatta atatctaata
    31681 ccacactggc aaaaacaaca ttaaaactga gtcataatca ggataaaagc catgctgtcc
    31741 ataaagcatt aagctattta gcggataaaa ccaaagagta ttctaatggt gaattagtta
    31801 ttcgcattta cccaaatgcg acattaggta atgagcgtga atcactggaa ttaatgaact
    31861 ccggtgcatt acagatggtt aaggttaatg ctgcatcact agaatcattt gctccggatt
    31921 acagcctttt cagtctgccg ttcttattcc gcgaccgtga tcactattat cgtgttctgc
    31981 aaagtgattt aggtaaaaaa atacttaatt catcagaaag caaaggtttt gttggtatta
    32041 cgtactatga cggcggtgcg agaagttttt attccaataa accgattaca aaacctgaag
    32101 atttagcggg aatgaaaatc agggttcaac aaagccccag cgccattgca atgatgaaag
    32161 cactcggtgg tgtcgctacc ccgatggcgc aaggcgaact ctacaccgca cttcagcaag
    32221 gagtggttga tggcggagag aacaataccg ttgtctatgc cgatatgcgt cacgccgaag
    32281 tcgcaaaagt ctattcacgt gatgaacaca ccatggtacc tgatgtgtta attatcagca
    32341 ccgacgtgtt aaataaactt ggtgataaag agcgcacggc attattaaaa gcagccgatg
    32401 agtcaatgat gcagatgaag gacgtcatct ggcctgcggc tgaaaaagaa gcctacgaca
    32461 aaatgaaagg gatgaacgca acagttgttg atgttgataa atccgctttc aaagaacgcg
    32521 tcaaaccgtt atacgatgaa ttcaaggcga aagatgcaca atcagccaaa aaccttgagc
    32581 tagtagaaag tatgtaaccc taatgggcag gtaattcctg ccttttcatg gaagacttat
    32641 gcgaacactc actcatattc ttaataagat ccttgccgga tgttgctgca ttattctcgc
    32701 cattatggtg ttctgcgtaa cctggcaagt tattgcacgt tttattttta acgctcccag
    32761 cactgtgctt gatgagttca cccagatttt atttatgtgg atgattttac ttggcggtgt
    32821 atatactgcg gggttaaaaa aacatctggc cattgatttg ttggctcaaa aacttccggc
    32881 tgcatctgtt ctgacgcttg acagttttat ccaaattatt attacggtct ttgcggttat
    32941 tttcatgatc tatggcggga atattgttgt tgaaaaagca caacatgttg gacaaatctc
    33001 tccagtatta aaatggccaa tggataaagt atattgggtt atgcctgtca gtgggcttat
    33061 tctggtctgg tattcagtaa tgaatattat tgacaactat cgtaaacgga attttcatta
    33121 acgagggaaa tatggacttt gaatatatct accccgtctt aattttattt ggcagttttg
    33181 ccgtcatgct ggcaataggt gtgccaatta cttttgcgat tggtctttct tcgctgttat
    33241 ctattattac tgccttacca cccgatgccg ccatttctgt gatttcgcaa aagatgactg
    33301 tggggctgga tggctttacg ctattagcca ttcccttctt cgtgttagcc ggaaacatta
    33361 tgaataccgg tggtatagcc agacgactgg ttaacctggc gcaagcatta gttgggcgtc
    33421 ttcctggctc actggctcat tgtaatatcc tcgcgaatac actgtttggt gcgatttcag
    33481 gttcagccgt tgcgtcagcc gccgcggtag gtgggattat gtcaccactg caagaaaaag
    33541 agggatatga tccggcgttt tcagcagcgg ttaatattgc ctctgccccc attggcctga
    33601 tgatcccacc gagcaatgtg ttgattgttt attcccttgc cagtggcggg acttctgtcg
    33661 ctgcgttgtt cttagctgga tatctgccgg gcatcctcac cgctgttgcc ttaatgtttg
    33721 tagctgcact ttatgcccga cgtcaccatt atccggtggc cgagcgcatt aattaccgtc
    33781 agtttttaca ggtattccgc gaatcaattc ctagcctgat gcttattttt atcattattg
    33841 gcggtattat cgcgggggta tttacgccta cagaagcatc ggcaattgcg gtaatttata
    33901 gtttagccct ggcgatgatt taccgggaaa tcactcttaa gaagctcaat gatattctgt
    33961 tagattcggt agtaaccagt tcaattgttc tgttactggt aggctgctcg atggggatgt
    34021 catgggccat gacgaatgct gatgttcctg agttgatcaa cgaactgatt acccgcgttt
    34081 cggataacaa atgggtcatt ctgtttatta tcaatatcat tctgttgatc gttggtacct
    34141 ttatggatat cacgccggcg atcctgatat ttacacctat tttcctgccg atcgcccagc
    34201 atctggggat tgatccgatt cacttcggca tcattatggt tttcaactta accattggcc
    34261 tttgcacacc acctgtcggc accattctgt ttgtgggatg cagcattggt aaggtcagta
    34321 tcgacagggc aataaaacca ttactgccga tgtttctggc attgtttgta gtaatggcaa
    34381 ttatttgtta tttcccgcag cttagtctga tgctgccagg attattttcg acctgataca
    34441 caatgaagac tgcatactga gtaattttca atgccccacc actctgtggg gcattgaatt
    34501 ggtccattac ggtaccggat tgaccaacag ttgcccaatc gagccacggt ccgccatttc
    34561 cagcgtctga ctgttgaagt agaacgggaa gtgcgcccag gaaggctgac cgaaataaac
    34621 aagcagctcc acttgtccgt caacccaaac ggtatctttc cagcctctgt cttccgggaa
    34681 cggcatcgcg ccattcacgt tacggatctg gaacatcacg ccttcaatat ggaacgcttg
    34741 cggctcgtcc gcgcgcaccg tccagcgttc ccacgttcct tgctgcgcag taacatcaat
    34801 acggttgacg tcccacaact gcccattaat ccccgggtca tcacccagac tgatatcacg
    34861 acttcgaatc ggcgaaccgg ccatgatttc agttggcagc aagcgcatcg gaagactgtc
    34921 tgtgaccagc ggcagaaggc cggttgggcg cagcgttagc accagcgtag aaaccagaat
    34981 gctggatggc tcaaagaagc cacgaatacg atcaacaatg ctcgccgctt cgccacaggt
    35041 aatcgacact tcatcaccgt tgctcatatc caccagaatc tcacgacgct cgcccggtgc
    35101 cagcgaaagt tgcttcaccg atacaggagc gggcaggaat ccctgatcgc cagaaatcac
    35161 atgtaacggg cgaccatcgc tcatctgtag ttgatagcga cgagagttcg acgcgttcaa
    35221 cagacgcaag cgcacccagc cacgcgagac ttcaacgtac gggctttgta caccgttaac
    35281 cagtagcgta tcgccaacaa agccgccgct tccaggttcg ttatattctg gcgtaccaaa
    35341 gttatccagc cgtttatcct gaataatgac aggaaaatca tccacaccat aatggttggg
    35401 gataggcagc gatttactga cttcatcttc caccagccac attccggcaa ggccgttata
    35461 gacctgctga gccgtgcggt tgggagtatt ggcgtgatac cacagagtag ctgcgttctg
    35521 gcgaatgggc agtacgggtg cccagtcagc gtttggcgac atcatccgtg ccggaccgcc
    35581 catcagcggg ccaggtacct gtagcccggc caccgtcatt gagacatttt ctgtcaggcg
    35641 gttgctgtaa ataagcttaa catcgtcgcc cttccagacg cggatagtcg gccccaggta
    35701 acgaccattg attccccaaa ccgacgcgcg tgtccctggc gtaaatgacc agtgcgcacg
    35761 ttgtacagtc ataaacagcg gttgcccacg gcgagattca agcagcggcg gaacgggtag
    35821 cggttgctgt tgcccggctg cgctggcctt caggggaaca gcgcctgcac aaagtgcaat
    35881 ccccgatgcc tgaatgaact gacgccgact gagtgacata tttgctccat gtaaaactgg
    35941 ctaaagtaat accgtgcagg aaagtgttcc ccgcaaaaat acagattgcc gacttaaact
    36001 tttccggcgg cttcgcgttc tgcgacttct ttatcgagct cggcgatttt ttgttccatt
    36061 atcgaacgac aatgggcagc caactcgcga acctgatctt tgccatactg actgacgtca
    36121 attggcggca gcatttcgac aatcaccaga ccgttgtgta gccgattaag attaatctta
    36181 ttcgaagttg tagagacgca cacgggtata atcgggacgc ccgccgcaat tgccgcgtga
    36241 aatgccccgg tcttgaacgg cagcaggccg cgaccacggc tgcgggttcc ttccgggaac
    36301 atccagatgg aaatacggcg ttttttgaag tgattcacta cttccgcaat agtgccgtga
    36361 gctttagtgc gattgtttct gtcgatcaat aagttgccgg ttaaccaata caactgcccg
    36421 aagaagggga tccacagcaa actcttttta cctaccgtca ctgtcggcgg ctgcacaatg
    36481 ttcgatgccg tcaccatgtc ataattgttc tggtggttag caatatagat agcattgccg
    36541 tagttttcag cgtctgcagg tttgcggcac tccactttca ggccgaaaag cggcgcaaga
    36601 cgaccaaaca tatgcccaaa ggtggccaca tgtttcggat tacgcgggct gaaaaggcag
    36661 taaatggagc cgaatacaca gactaagatg ctgtaaatca cggtaataat aagacgaaag
    36721 atatatagca taacaccctc tgaaggtctg agagactggc attgtacgtc acctgaaaat
    36781 caggttaggg cattgttaaa agccgctctc tggaaaagcg tattgttaat cgcaacgcat
    36841 gaataaacaa cggtttcaag ggaattttta tcgtttccgg ggattgaata cgctgccgga
    36901 tgacgactta acgtttcatc cggcgttcct tgcaagcggg aggaaacagc gccctccccg
    36961 gcatattact cttcgctatc accgctgctg gcacggcgag gagagtcgat ctcaacacga
    37021 tcgatacgct gcaaaccgcg catcaacgta ccgcggcgtc cacgttcgcc agtgactttc
    37081 tgtagctctt ccggacgcag tttaattttg cgtttcccaa catgaatggt cagcgtgctt
    37141 tgcggcggca gaacgtacag ttgcgccagg ccatcctcgc cacgcgcggc ttctgccgat
    37201 ggaatgttga taatcttgtt gcctttgccc ttcgacagct gcggcagatc gcttaccggg
    37261 aacatcaaca tacggcctgc ctgagtgatt gccagcagca tatcggaagc atcttcaatc
    37321 accaccggcg gcataacatg ggcattttcc ggtaaggtga tcaaagcctt acctgcacgg
    37381 ttacgcgcca ccagatcgtt aaaggtgcag acgaaaccgt aacccgcatc ggaagccatc
    37441 agcagtttct gatcgtcgct ttccatcagc atatggtcaa cggtcgctcc aggcggcaac
    37501 gttaatttgc cggtgagcgg ctcgccctga ccacgcgccg acggcagcgt aatcgggtcg
    37561 atggcatagc tacgaccggt ggaatcaaca aacactaccg gttggttgct cttacctttc
    37621 accgccgctt tgaagctatc acccgcttta taattcaggc ccggcgcgtc gatatcatgg
    37681 cctttagcgc tgcgtaccca gcccatctgc gacagcacaa tggtgacagg ttcagacggc
    37741 agcatgtcgt gctcgctcat cgctttcgct tcttcgcgtt catgcaacgg cgaacgacgt
    37801 tcgtcaccgt agccttgcgc gtctgcctgc agttctttct tcagcaggtt attcatttta
    37861 cgctcggaag ccaaaatgcc ctgcaactgg tcgcgctctt tttccagctc actctgctca
    37921 ccgcgaatct tcatctcttc cagtttggca agatgacgca gtttcagttc gaggatcgct
    37981 tccgcctggg tttccgtaag gccaaaccgc gacatcagcg ccggtttcgg ttcatcttca
    38041 ttacgaatga tctcaatcac ttcgtcgata ttgagaaacg ccaccagcaa accttcgagg
    38101 atatgcaggc gcttgagaac tttctccaga cgatagttca gtcggcggcg cacggtatcg
    38161 cggcggaaca ccagccattc ggagaggatt tccagcaggt ttttcaccgc cggacgacca
    38221 tccagaccga tcatattgag gttaatgcga tagctctttt ccagatcggt ggtagcaaag
    38281 aggtggttca tcacctgatc catatccacg cggttggaac gcggcacaat caccagacgg
    38341 gtcgggttct cgtggtcaga ttcatcgcgc agatcgtcaa ccatcggcag ctttttgttg
    38401 cgcatttgcg cagcaatttg ctccagtacg cgcgcacctg aaacctgatg cggcaatgcg
    38461 ctgataacca ccgcgccatc ttccttcttc caaaccgcgc gcatacgcac tgaaccacgt
    38521 ccgttctcgt agattttacg aatctcggcg cgcgaagtga taatttccgc ttcagtcgga
    38581 taatccggcc cctgcacgat atccagcagc tgatcgagcg tggttttcgg ctggtcgatt
    38641 aaggcaatta ccgcctgagc cacttcacgc aggttatgcg gtggaatatc ggtcgccatg
    38701 ccgacggcaa taccggtggt gccgttaagc aaaatgtttg gcagacgggc aggcagcatt
    38761 ttcggctcct gcaaagtgcc gtcgaagttt ggcacccagt cagccgtccc ctgccccagc
    38821 tcgctcaata gcagctcgga atatttcgac aaccgggatt cggtgtaacg cattgccgcg
    38881 aacgatttcg gatcgtccgg cgccccccag ttcccctgac catcaaccag cggataacgg
    38941 taagagaacg gctgcgccat caggaccatc gctacataac aggcaatatc gccgtgcgga
    39001 tggtatttac ccagtacgtc accgacggta cgggccgatt ttttaaattt ggcgctggca
    39061 ttcaggccca gctcagacat cgcatacaca atgcggcgct gaacaggttt cagaccatca
    39121 ccaataaacg gcaacgcacg gtccatgatc acgtacatgg agtagtttaa gtaggcgttt
    39181 tccgtaaatt catgtagcgc aaggcgctct gccatatcgc tcattaattc tgattcctca
    39241 acttattcgc cagccttcaa aggggcaata ttgccggaga tactacatta tctgccgcgt
    39301 cgagtcacag gagatcagcg tgaatagcgc cgccggacgt gctccggcgg cgataaaggc
    39361 atcaatgtgc cttgatatac aactctttgc tgtagacata atcctgggga ttatgcagcg
    39421 gaaaaccgcc aacgtagggt ttaagcagtt tgattaacgg ctgatagtag atgggaatca
    39481 gcggtgcctg ctggttgatg atcacttctg cctgctgata cagcgcatta cgctttgttg
    39541 catcagccgt ttgtgccgcc tggtttagta aggcgtcata ctgcgcgttt ttccagtggc
    39601 cgacgttttc ttcactatcg cttttgagcg tgttcaggaa gctggaggca tcattgtacg
    39661 tcgcatccca cgactgccga gacagcataa aatcaccggc tcgtcgggca tcaagatagg
    39721 ttttccactc cattgtgcgc agcgtcacct gtgcacccag ccattttttc cattcggaag
    39781 acaacgctat cgcggtcttt tcatgcagat cgtacttgtt gtagaacagc tcaaagcgta
    39841 gcggatgaga ggcgtcgtat cccgcctgtt tcagcaagac ttttgccatc gcgacgcgct
    39901 cactcattgg cttttgcagt tcatcgaacg tcgtcgcgct aaagcctttt acctctggcg
    39961 gcgtcagcgt ggttgcgggc gttctcaacc ccagtacctt ttgcgcaata agctgtcgat
    40021 caaccgtaag atatagcgcc cgacgcaccc gcacatcgtt aaatggcggt ttctcaaggt
    40081 taaagttgta atattcgctg ttcagacgcg ggataattcg tagctcgcca ggcagtgatt
    40141 tttcaatggc gggaatttgc tgcgccggaa cccaggtgag atcgacctct cccgcgcgat
    40201 agcggttata gccggtgacc gaattatcca gcgccagata ctcaacctgt tgcaatactg
    40261 tatgttgcgc atcgcggtac tttggatttt tgcgtgcagt aatcttttcg ttaactaccc
    40321 atttatcaag cacaaaggca ccgttgtaaa ccatgttctc tggcttactc cagctatcgc
    40381 catgtttagc gatgacatga tgaggaaccg ggaacagcgt cggccaggcg agcatcgtcg
    40441 tgaaccaagg aaccggctgc tcaagcgtaa cttcaagagt acgatcatcc atcgctttga
    40501 cacccagcga tgtaacatct gctttacccg caacaatagc cgcggcattg ttaatgtgcg
    40561 cctgtgccag atagccagca aaagggcttg ccgttttcgg gtcaaccgcg cgctgccagc
    40621 cgaggacaaa atcctctgcc gtcagaggct gaccgtctga ccactgcaaa ccgctacgca
    40681 gatggaaaat atagcgcttg ccgccgtcaa gtatctccca gcgttcagcc tgagcgggct
    40741 gcacctggcc ttcaccgtcc atccatacca gaccttcaaa cagatccagc acaatctgcg
    40801 cggcggtatt ctcctctacc ttttgcgggt cgagcgtgcc tgggtcgcta tgattgttgt
    40861 aacgaaagac ttgttgcggg gcgagcggtg tgttggcggg aacgtcagca gcgtagagag
    40921 gagccgcact taccaggctg accagccata ataaatttcg cgtatacatg gtattcctta
    40981 ccggagaaat tataagcccg acaacaatac gcctgtggca ttgtttgctc aaacttatcg
    41041 cgagtgattt ggctcacact ccggtaaaga ttccccatca cgctaacggt acataaacat
    41101 ccatttccag tcgctgctct gtcatccctt cggcaagatt ggtgtagtga aacagaatcg
    41161 gtgctttacg cattttctcg ccgcttgcag gcagccagtg gcgaatgatg ccccatatcg
    41221 tgtgtgaaat atcgtccagc tcgccaacat ggcgggccac agcataacgt ccaccggtaa
    41281 gttcaccatt acttacgcca taacgattat cggggatcgg ttcgctaacg ctgccgcaga
    41341 tatcaaagcg aaacgcatct ggtgcggtgg tggcagggtc gtcccaggcg acgccaaaag
    41401 tctggctttg gttaacagga gaaagccccg tctctttacg ccacatgata aatttcgcca
    41461 cgctgtagtt gagcaactca gggctacagc ggtgcggcaa catcgccaca gggattgatg
    41521 ggaaatcgat aatatttaca tccagtgtca ggtttgtcat tttgcctccc tgcgaaatta
    41581 ttcccgggaa cgcgtcccgg gagcggtaac aattacggat ttactttgcg gatctgtttg
    41641 acgtcaattt caacagagtt ccagtcttta tcgacttcac cctgaatctc aaccgtatct
    41701 ttcggcgtca ccgtcacgcc gttccagcgt ttatggtcga tatcaacatt gatagtaccg
    41761 ctggcatctt tgaacacgta gagatcgtca gagatgcgtt caacgatatt gccgcgtagg
    41821 gttacccagg tgtcgtcacg cagggatttt gcgctttcta cagtcgttac gctgccgttc
    41881 ggcccctgga atcctccggc ctgactttgc gttgccgatg ggccagaaaa acctccctgc
    41941 tctgctgcca taaccggtgc actgcacagg gccattactg cgattactgc tgcgaatttt
    42001 ttcatgttta ttactccctt taatgtctgt ttccgagcat ttaacaagat agtccttaac
    42061 aacttcttaa gggaaaaaaa taaaatttaa tgctgtacag agcgcgttac aacacggttt
    42121 actggcagca aatacggtta tcgcagggat gaaaaaatgc gaattttact gatagaagat
    42181 gacatgctga ttggcgacgg catcaaaacg ggccttagta aaatgggttt tagcgtcgac
    42241 tggtttacac aaggtcgtca gggaaaagag gcgctatata gcgcacctta tgatgcggtg
    42301 atcctggatt taaccttacc aggcatggat ggtcgcgata ttttgcgcga atggcgagaa
    42361 aaaggtcagc gtgagcctgt attgatcctg actgcgcgcg atgcgctggc ggaacgtgta
    42421 gaagggctgc gtctgggagc tgacgattat ctgtgtaaac cttttgcgtt gatagaagtc
    42481 gccgccaggc tggaagctct gatgcgccga accaacggcc aggccagcaa cgagctgcgc
    42541 cacggcaacg tcatgctcga ccccggcaaa cgtatcgcca cgctggctgg cgaaccctta
    42601 acgctgaaac caaaagaatt tgccctgctg gaattactga tgcgtaacgc tggtcgggta
    42661 ctgccgcgca aactgattga agagaaactg tatacctggg acgaagaggt caccagtaat
    42721 gccgttgaag tgcatgtgca tcatctgcga cgcaaactcg gtagtgattt tattcgtacc
    42781 gtgcatggta ttggctacac attaggtgag aaatgaaatt tacccaacgt cttagtctgc
    42841 gagtcaggct gacgctaatc tttttaattc tggcctcggt gacctggctg ctttccagct
    42901 ttgtcgcctg gaaacaaaca acggataacg tcgatgagtt gttcgacacc caactgatgc
    42961 tgtttgccaa acggttaagt acgctcgatc tcaacgaaat caacgcggcg gatcgcatgg
    43021 cacagacgcc aaataaatta aaacacggtc atgttgatga cgatgcgctg acttttgcca
    43081 tctttaccca cgacggcaga atggtcctta acgatggcga taacggagaa gatattccct
    43141 atagctatca gcgggaaggt tttgctgacg ggcaactggt cggtgaagac gatccctggc
    43201 gttttgtctg gatgacctca cctgatggca aatatcgcat cgttgtgggt caggaatggg
    43261 aataccgtga agacatggcg ctggcgattg ttgccggaca attgatcccg tggctggtcg
    43321 cactgccgat tatgttaatc atcatgatgg tgctactggg tcgtgaactc gcgccgctga
    43381 acaaactggc gctggcacta cgtatgcgtg acccagactc ggaaaaacca ctaaacgcga
    43441 cgggcgtacc cagcgaagtg cgcccactgg ttgagtcgct aaatcaactg ttcgcccgca
    43501 cacatgcgat gatggttcgt gaacgacgct ttacctccga cgcagctcac gaacttcgta
    43561 gcccgttaac ggcgctgaaa gtgcaaaccg aagttgctca gctctctgac gatgatccgc
    43621 aggcgcggaa aaaagcgctg ctccaattac attccgggat cgatcgcgct actcgtctgg
    43681 ttgatcaact gctcacgcta tcgcggctgg actcactgga taaccttcag gacgtcgcgg
    43741 agatcccgct tgaagatctc ctgcaatcgt cggtgatgga tatttaccac acggcgcagc
    43801 aggcgaacat tgacgtgcga ctgacactca atgccaacgg catcaaacgc accggacaac
    43861 cgctattgct aagtttgttg gtgcgaaatt tgctggataa cgccgtgcgt tacagtccac
    43921 aaggtagcgt ggtagacgtc acgctgaatg ccgataattt catcgtgagg gataacggcc
    43981 ctggtgtgac accagaggca ctggcgcgaa ttggcgaacg cttctatcgc ccacccggac
    44041 aaaccgctac cggcagtgga cttgggctat cgattgtcca gcgaatcgcc aaattgcatg
    44101 gcatgaatgt tgattttggg aatgcgaaac aaggtggatt tgaagcgaag gtaagctggt
    44161 aacttctctg tctatgagag ccgttaaaac gactctcata gactttacta atagcaaaat
    44221 ataaaccgtc cccaaaaaag ccaccaacca caacccagac aaataacgag cgagaataca
    44281 tatagccaaa actcgaacat ttcccgcata aagagttttc ttaagataag aataataagt
    44341 ggtgtcagaa gaaaaaatgc tgcaatcatt gcttgtaata tacgatcttc gcctgaaaca
    44401 gaaggtatac tgcaaatatt gtctcccgac tcaagcatcc agtcatactt attgaaagca
    44461 aaaaaagaat ctattaacca ataagtaagc attatatata atagtgcttc aaatattgat
    44521 agtagttgtt tttttaacat atctgattac tcattaatca attttttgat atgttctcta
    44581 atctctaaca acctcatacc ataagagatg aatttataat catctgtatc acgcgcaggc
    44641 aaattattaa ttaaacaaat aaaaaaaccc aaatctcgtt caacaccacg attatatcta
    44701 ataccagcca taatatactg ctcattcgtc atatacagtg ttgccgaaga gggataatca
    44761 aaaagaacaa gatctcttaa ataagtagca gcaatttgaa aggtaaaatc atcctccatt
    44821 aggcatgtcg ctaactctaa ctgatttctg gtagttaatt ctgaagggtc tagacctaga
    44881 gtaatcgctg cggttcgtat ttgtataccc attgagccaa atgatgtttt attttcaggc
    44941 atatctaaca atccgatcat tctttttgtt tcatatatct gaaacttata attttcaggc
    45001 atacctcctg actcaatcca ggccacgccg cccagtaact ctggacgaat tccagcggcg
    45061 tatgcatatt taattatttt gtctctatta tat
//
LOCUS       DAFGPF010000029        43712 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFGPF010000029 DAFGPF010000000
VERSION     DAFGPF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43712
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.029"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(23..1477)
                     /gene="xylB"
                     /locus_tag="LSX49_001814"
     CDS             complement(23..1477)
                     /gene="xylB"
                     /locus_tag="LSX49_001814"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBL7168236.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDDMLQACHLSRDQMPALYEGSEITGALLPEVAK
                     AWGMAAVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALITAARQADESAEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            complement(1548..2870)
                     /gene="xylA"
                     /locus_tag="LSX49_001815"
     CDS             complement(1548..2870)
                     /gene="xylA"
                     /locus_tag="LSX49_001815"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBL7168237.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK"
     gene            3236..4228
                     /gene="xylF"
                     /locus_tag="LSX49_001816"
     CDS             3236..4228
                     /gene="xylF"
                     /locus_tag="LSX49_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7168238.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVVKDGFHKESEL"
     gene            4306..5847
                     /gene="xylG"
                     /locus_tag="LSX49_001817"
     CDS             4306..5847
                     /gene="xylG"
                     /locus_tag="LSX49_001817"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HBL7168239.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVSLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALKKFTGSISQLDDAAEQKCILESIQQL
                     KVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            5825..7006
                     /gene="xylH"
                     /locus_tag="LSX49_001818"
     CDS             5825..7006
                     /gene="xylH"
                     /locus_tag="LSX49_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HBL7168240.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            7084..8262
                     /gene="xylR"
                     /locus_tag="LSX49_001819"
     CDS             7084..8262
                     /gene="xylR"
                     /locus_tag="LSX49_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XylR"
                     /protein_id="HBL7168241.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
                     "
     gene            complement(8370..9194)
                     /locus_tag="LSX49_001820"
     CDS             complement(8370..9194)
                     /locus_tag="LSX49_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HBL7168242.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            9514..11544
                     /gene="malS"
                     /locus_tag="LSX49_001821"
     CDS             9514..11544
                     /gene="malS"
                     /locus_tag="LSX49_001821"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HBL7168243.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGEYTLQLDTRSGTPT
                     LMISIQNAVEPVASLVRECPKWDGLPLTLDVSATFAEGAAVRDYYSQQIAIVKNGQIT
                     LQPAATSNGLLLLERAETDTSAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGSEADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGDEVKKTLGERWNDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKTDTHAKIIDGFTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALHEWKKANPDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCLAQMDTTWQQMAEKLQDFNVLSYLSSHDT
                     RLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ASVAHWQKISQFRARHPAIGAGKQTTLSLKQGYGFVREHGDDKVLVIWAGQQ"
     gene            11722..12975
                     /gene="avtA"
                     /locus_tag="LSX49_001822"
     CDS             11722..12975
                     /gene="avtA"
                     /locus_tag="LSX49_001822"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HBL7168244.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPEKIEAGVKILAEEIERAWAESH"
     gene            complement(13014..13487)
                     /locus_tag="LSX49_001823"
     CDS             complement(13014..13487)
                     /locus_tag="LSX49_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL7168245.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHQENQDCAALSPDEFISRI
                     RVIKDHSWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQSRCIGCKSCMLACPFG
                     AMEVVSSRKKARAIKCDLCWHRATGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(13589..14437)
                     /gene="yiaJ"
                     /locus_tag="LSX49_001824"
     CDS             complement(13589..14437)
                     /gene="yiaJ"
                     /locus_tag="LSX49_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HBL7168246.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWESHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DQGAIT"
     gene            14638..15636
                     /gene="yiaK"
                     /locus_tag="LSX49_001825"
     CDS             14638..15636
                     /gene="yiaK"
                     /locus_tag="LSX49_001825"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HBL7168247.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMCGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTEDNSDEYGISQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            15648..16112
                     /locus_tag="LSX49_001826"
     CDS             15648..16112
                     /locus_tag="LSX49_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBL7168248.1"
                     /translation="MIFGHIAQPNPCRLPAAIEKALDFLRTTDFNALDPGVVEIDGKN
                     IYAQIIDLTTREAVENRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRDI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPACNKNATTAIRKIVVKVALAAL"
     gene            16135..17055
                     /locus_tag="LSX49_001827"
     CDS             16135..17055
                     /locus_tag="LSX49_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4862 family protein"
                     /protein_id="HBL7168249.1"
                     /translation="MKTNNAGYIIGAYPCAPSFHQRSEEEEKDFWRQLSETPDILGLE
                     QPCLENFHPLGDQWLLRHTPESWKFVVTAVMETMRRRSENSGFGLASSDEEQRQACVA
                     YYRHLFNKINALQANKVLALALQAAPLATNPNVMQATDAFARSLKEIASWDWPCKLVL
                     EHCDAMTSSSPRKGFLPLENVLEVITDYDISICINWARSAIEGRNTTLPLTHTQMAKQ
                     AGKLGALMFSGTTLNGAYGEWQDLHAPFAPFCAESLMTTDHVRELFNVAESSTLHFAG
                     IKLLEINATADVHHRIEILRNGIHSLNESR"
     gene            17169..17636
                     /gene="yiaM"
                     /locus_tag="LSX49_001828"
     CDS             17169..17636
                     /gene="yiaM"
                     /locus_tag="LSX49_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HBL7168250.1"
                     /translation="MKRILEGILAIIIAILSCIIFINIILRYGFHTSILSIDELSRLL
                     FVWLTFIGAIVAYMDNSHVQVTFLVEKLSPANQQRVSLLTHTLILLLCLGLAWGAIEK
                     TAQDWSNLSPILGVPVGLMYAAAIPTSLIIALLELRHLYRQFTNTPSRNQQGA"
     gene            17639..18916
                     /gene="yiaN"
                     /locus_tag="LSX49_001829"
     CDS             17639..18916
                     /gene="yiaN"
                     /locus_tag="LSX49_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HBL7168251.1"
                     /translation="MTILIFIVSLLGAIAIGVPIAWALLLCGISLMFWMDIFDVQILA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSQRIVDLPMKLVGHRPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRQANYPVNRAAGLIGSGGIIAAIIPPSIPLIIFG
                     VSSGLSISKLFMAGIAPGIMMGVTLMVTWWWQAKRLNLPCQPKASLREVWQSLVSGIW
                     ALFLPIIIIGGFRSGLFTPTEAGAVAAFYALFVSVVVYREMTFSTLYHVLINAAKTTS
                     VVMFLVASAAVSAWLITIAELPMMVSELLQPLVDSPRLLFIVIMLAIMVISTVMDLTP
                     TVLILTPVLMPLVKEAGIDPVYFGIMFIINCSISLITPPVGNVLNVVCGVAKLKFDDA
                     VKGVAPYVMVLFMLLALFIFIPELITAPLKWMS"
     gene            18929..19915
                     /gene="yiaO"
                     /locus_tag="LSX49_001830"
     CDS             18929..19915
                     /gene="yiaO"
                     /locus_tag="LSX49_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HBL7168252.1"
                     /translation="MKLRSVTYALLIAGVATFSTSSLAAQSLRFGYETSQTDSQHIAA
                     KKFNELLQEKTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFTGLSPVIN
                     LLDVPFLFRDTAHAHKTLDGKVGDDLKVSLEGKGLKVLAYWENGWRDVTNSRQPVKTP
                     ADLKGLKIRTNNSPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAK
                     FFEVQKYLSLTHHAYSPLLVVINKAKFDGLTPEFQQALISSAQEAGSYQRKLVAEDQQ
                     KIIDGMKEAGVEVITDLDRKAFSDALGTQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            19919..21415
                     /gene="lyxK"
                     /locus_tag="LSX49_001831"
     CDS             19919..21415
                     /gene="lyxK"
                     /locus_tag="LSX49_001831"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HBL7168253.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQCCTAVIRSLLTHSGVSGEQIVGIGISAQGKGLFLLDKNDKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSRGEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAVLTGLKAGTPVVGGLFDVVSTALCAGLEDEFTLNAVMGTWAVTSGITHGL
                     RDGEAHPYVYGRYVNDGQFIVHEASPTSSGNLEWFTAQWGEISFAEINQAVASLPKAG
                     GALFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTRVYRDFSE
                     AQRDLQHPVRTLLPDMAAHQLYQQKYQRYQHLIAALQGYHARIKEHTL"
     gene            21412..22074
                     /gene="ulaD"
                     /locus_tag="LSX49_001832"
     CDS             21412..22074
                     /gene="ulaD"
                     /locus_tag="LSX49_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL7168254.1"
                     /translation="MSRPLLQLALDHSSLEAAQRDVTLLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QNCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKEIRVKAFIAGRSLAGAANPAQVAADFHAQIDSIWGGK
                     RA"
     gene            22067..22927
                     /locus_tag="LSX49_001833"
     CDS             22067..22927
                     /locus_tag="LSX49_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBL7168255.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSAAQRASLVTAMLETGVAIPSMCLSAHRRFPFGSRDDAVRQRAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTE
                     HSPGQFRDVPFGEGCVDFVGIFKTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            22921..23616
                     /gene="araD"
                     /locus_tag="LSX49_001834"
     CDS             22921..23616
                     /gene="araD"
                     /locus_tag="LSX49_001834"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL7168256.1"
                     /translation="MLEQLKADVLAANLALPVHHLVTFTWGNVSAIDETRQWMVIKPS
                     GVEYEVMTADDMVVVEIASGKVVEGSKKPSSDTPTHLALYRRFAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRLMTAEEINGEYEYQTGEVIIKTFEERGLNP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(23648..24463)
                     /locus_tag="LSX49_001835"
     CDS             complement(23648..24463)
                     /locus_tag="LSX49_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7168257.1"
                     /translation="MLELSMTLPIKVQNGGLFISRGVGRHPARRLESWEIIFVEKGRL
                     TIQEDERIFLVDAGESLLLWPNRQHVGVEDFPADLKFYWLHFEVKAPDNDPRWLTHLS
                     VPQQTKVADPQVLVALFRQFLSEQEKHQRTPALEFIVLLILQQLTRDARLDEQADGAG
                     TTLAWKAQKLIRTQYHRPLSTALLARELYCNADYLGRVYRRVFHLTLTEAIHRQRVRE
                     AEKLLISEARSLTEVAALCGFNDVGYFRQIFRKHTGLTPAAWKRRYSKEHINS"
     gene            24689..26089
                     /locus_tag="LSX49_001836"
     CDS             24689..26089
                     /locus_tag="LSX49_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7168258.1"
                     /translation="MTSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMN
                     FLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMGVIADRTQSRWGRFRPWQLWIAI
                     PIGIIGILTFTVPDASMGVKIAWAFGTYLLLSVGYTAINVPYCALINTMTTRHNEVIS
                     CQSWRFVLCGVAGFLVSVGLPWMVDLFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWV
                     RERVPLSTMGKFTLREHLAGLRNNDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQG
                     STGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLAALAVLMWFLPSSPA
                     YQTLWLVVILGNGVILGFTLPLHFSLMAFADDYGEWKTRVRSSGMNFAFNLFFIKLAW
                     ASSAGIISLLFIFVAYQPGVENQTASSLGGIAAMETLLPALFHLLLAMAIRFCKLNNP
                     MMSRIASDLRQRHVQP"
     gene            26100..28073
                     /locus_tag="LSX49_001837"
     CDS             26100..28073
                     /locus_tag="LSX49_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001026880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
                     /protein_id="HBL7168259.1"
                     /translation="MNISEVDLHKLTVSDPFLGQYQQLVRDVVIPYQWDALNDRIPEA
                     EPSHAIENFRIAAGLQEGEFYGMVFQDSDVAKWLEAVAWSLCQKPDAELEKTADEVIE
                     LIASAQCEDGYLNTYFTVKAPEERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLE
                     VVCRLTDHIDSVFGPDESKLHGYPGHPEIELALMRLYEVTEEPRYLALTNYFVEQRGA
                     QPHYYDQEYEKRGQTSHWHTYGPAWMVKDKAYSQAHLPIAQQQTAIGHAVRFVYLMTG
                     VAHLARLSHDESKRQDCLRLWNNMAQRQLYITGGIGSQSSGEAFSSDYDLPNDTVYAE
                     SCASIGLMMFARRMLEMEGDSQYADVMERALYNTVLGGMALDGKHFFYVNPLEVHPKS
                     LKFNHIYDHVKPIRQRWFGCACCPPNIARVLTSIGHYLYTPREDALYINIYAGNSMEV
                     PVENGTLRLRVSGNYPWQEQVTIAVESPQPVRHTLALRLPDWCIQPQIILNGEEVEQD
                     IRKGYLHITREWQEGDTLNLTLPMPVRRVYGNPLVRHVAGKVAIQRGPLVYCLEQVDN
                     GESLHNLWLPADAPFTTFEGNGLFRHKILIQAPGYRYEQSNPEQQPLWHYDSAPAKRQ
                     PQILTFIPWFSWANRGEGEMRIWVNEETSAIRR"
     gene            complement(28250..29788)
                     /gene="aldB"
                     /locus_tag="LSX49_001838"
     CDS             complement(28250..29788)
                     /gene="aldB"
                     /locus_tag="LSX49_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HBL7168260.1"
                     /translation="MTNNPPSAQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGEIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSYGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(29896..31191)
                     /locus_tag="LSX49_001839"
     CDS             complement(29896..31191)
                     /locus_tag="LSX49_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBL7168261.1"
                     /translation="MAIKSPPGLIPLSHLSGEELLAHLRFNRVTDEKGRYLPFDELQY
                     RIKKGENVDVAWTLTRLARNAAIQRINYCNEAGEQAGFNITPVIAEACELVDKRATAL
                     ALKDQTERLRGAGAELSQLRLEEPITSSQLEGANTTTLVARKMLETGRSPRTEDEHMI
                     AGNARLMAEIPHLLAEPLTPALIRQLHAIGMGGINDAKYRPGEFRETDDVVIADYDGN
                     IVHQPPAAALLPERLEKVCQWLNSHEGYIHPLVRACILHFMLAHEHPFRDGNGRTSRA
                     LFYWYMLKSGYDVFKYISISRLLHAAPVKYAASYQYTESDGMDLTYFLEYQAGVIKRA
                     LQNWQQHIDEITQRSAKLDSVLFSSGVLKRLNPRQVTLLNVMLANPGKEYTVAEISAS
                     LGVSDNTARADLRTIVKEGFAQEKRINNQQAVYVAHYPL"
     gene            complement(31321..32472)
                     /gene="yiaY"
                     /locus_tag="LSX49_001840"
     CDS             complement(31321..32472)
                     /gene="yiaY"
                     /locus_tag="LSX49_001840"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HBL7168262.1"
                     /translation="MAASTFFIPSVNVIGADSLNDAMNMMADYGFTRTLIVTDNMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
     gene            complement(32663..34507)
                     /gene="selB"
                     /locus_tag="LSX49_001841"
     CDS             complement(32663..34507)
                     /gene="selB"
                     /locus_tag="LSX49_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBL7168263.1"
                     /translation="MIITTAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGIDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRV
                     RALHAQNQPTETAHAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRIVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDIHSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPEK"
     gene            complement(34504..35895)
                     /gene="selA"
                     /locus_tag="LSX49_001842"
     CDS             complement(34504..35895)
                     /gene="selA"
                     /locus_tag="LSX49_001842"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBL7168264.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVTKAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQALLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            complement(35993..36601)
                     /locus_tag="LSX49_001843"
     CDS             complement(35993..36601)
                     /locus_tag="LSX49_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HBL7168265.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            complement(36672..37808)
                     /locus_tag="LSX49_001844"
     CDS             complement(36672..37808)
                     /locus_tag="LSX49_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBL7168266.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLEPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPNA
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
     gene            complement(37811..38173)
                     /locus_tag="LSX49_001845"
     CDS             complement(37811..38173)
                     /locus_tag="LSX49_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HBL7168267.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            38710..40623
                     /gene="mtlA"
                     /locus_tag="LSX49_001846"
     CDS             38710..40623
                     /gene="mtlA"
                     /locus_tag="LSX49_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBL7168268.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     KTSKVKEEDDIEAAARRVQEMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTENEVKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGRK"
     gene            40943..42091
                     /gene="mtlD"
                     /locus_tag="LSX49_001847"
     CDS             40943..42091
                     /gene="mtlD"
                     /locus_tag="LSX49_001847"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL7168269.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVDAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGTLPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            42091..42678
                     /gene="mtlR"
                     /locus_tag="LSX49_001848"
     CDS             42091..42678
                     /gene="mtlR"
                     /locus_tag="LSX49_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HBL7168270.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(42689..42898)
                     /locus_tag="LSX49_001849"
     CDS             complement(42689..42898)
                     /locus_tag="LSX49_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168271.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRQLYRPKQVEEK"
     gene            43182..43544
                     /locus_tag="LSX49_001850"
     CDS             43182..43544
                     /locus_tag="LSX49_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HBL7168272.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
BASE COUNT        10635 a        11437 c        11052 g        10588 t
ORIGIN      
        1 ccggtcaggc aggggataac gtttacgcca ttaatggcag aagttgctga tagaggcgac
       61 ggaacgtttc tcgtcgtggc tgataagcgg cataacgctg cgcatctggt agatgcgact
      121 gttctaacgg tagttgcggc aacaactcaa tgagcgattt ctctggattc gccgcaatct
      181 gcgccagcct tgctgcgccc agtgctggcc ccacatcgcc acccgtgcgg taatccagtt
      241 gctgaccgct aatgtccgcc agcatttgac gccagtactc actacgcgcc ccgccaccaa
      301 tcaacgtaac actttgcggt ttaatgccgc aggcatgcac gacatccatg ccatctgcca
      361 gcgcataacc cacgccttcc agcactgctc gcgccagttc attggggcca tgttgatgag
      421 tcaaaccaaa gaaaacccct ttcgcctggg gattattgtg tggtgtacgc tcgccagaaa
      481 gataaggcag aaaccaaact ggctcggcac tttcatcagc ctgtcgagct gcagtgatta
      541 aagcagggac attgctcagg ccggttaatt tcgcggccca atccagacac gaagccgcac
      601 tcagcattac agacattaaa tgccaacgtt gcggtaacgc atggcaaaag ctatgtacgg
      661 cgctttctgg cttgcttaag aacccttcgc tgacagcaaa atagaccccc gacgtcccca
      721 gcgataacat tgcctgatta gcatcaacca ttcccacacc aaccgcacca gctgcattgt
      781 cgccaccgcc tgcgacaact ggcaccgccg ccatacccca cgctttcgca acttcaggta
      841 gcaaagcacc agtaatttcg ctgccttcgt ataatgcggg catctggtca cgagataagt
      901 ggcaagcctg cagcatgtcg tcactccagt cacgctttgc gacatccagc cacatggtgc
      961 cagctgcgtc agacatatcg ctggcaaact cccccgtcat acgcagacgc aagtaatctt
     1021 tcggtaataa tactttatcg atttgacgga atatctccgg ctcatgccgc tgaacccata
     1081 gcaatttagg cgcagtaaat ccgggcatca tcaggttgcc ggtaatcacc cgcgattgcg
     1141 gaactcgcgc ttccagcaaa gtgcactctt gcgcacagcg cccgtcgttc cacaaaatgg
     1201 cagggcgtaa cacccgttgc tgagcatcca gtaaggttgc accatgcatc tgtccggcaa
     1261 tacctaatgc tttaacgtct tgcagagaat gctgaacgcc cagagctttc attgcgcgat
     1321 cagttgcctg ccaccactgt tccgggtctt gttccgacca gagtggatgc gggcgcgaaa
     1381 cggtcagctt ttccgtttgc gcagcaacca cctcaccctg ctcgttgagc aaaataactt
     1441 ttacgcccga ggtgccaaga tctatcccga tatacatatc gatcgttcct taaaaaatgc
     1501 ccggtatcgc taccgataac cgggccaacg gactgcacag ttaaccgtta tttgtcgaac
     1561 agataatgat ttaccagatt ttccagttgc tcctggcgac cactctgatg caccggagac
     1621 aaattatgtt cctgagcata tttggctaaa tctgccagtg acatttggcc tttcaggatt
     1681 tgctggccta attcactatt ccagccggaa taacgctgcg cgatgcgttt atccagctcg
     1741 ccatcttcaa tcatgcgcgc tgcaattttc agcgccaacg ccatcgtatc catcgcgccg
     1801 atatgaccgt aaaacagatc atatttatca gtactttgac gacgtacttt ggcatcgaag
     1861 ttcagaccac cggtggtgaa accgcctgct ttgagaattt catacatcac cagcgcattc
     1921 tcttccacac tgttcgggaa ctggtcggtg tcccagccca gttgcgcatc gccacggttg
     1981 gcgtcgacag aaccgaacag gccaagcgca atggcggtgg ctatttcatg atggaaagag
     2041 tgacctgcca gcgtcgcgtg gttagcttca atgttcagtt taatctcttt ttccagacca
     2101 aactgtttca ggaagccata gaccgtcgca gcatcgtaat catattgatg tttggtcggt
     2161 tcttgcggtt tcggttcgat aagcaacgtg ccctggaaac cgattttatg tttatgctca
     2221 accaccatct gcataaagcg gcccagctgt tcacgctcct ggcgcaagtc ggtatttaac
     2281 agcgtttcgt aaccttcacg accaccccac aggacatagt tttcaccgcc caatttatgg
     2341 gttgcttcca tcgctgtaac aacttgcgtt gccgcccaac tgaagacttc aggatctggg
     2401 ttcgtcgccg cacccgcgcc atagcgaggg tttgtaaagc agttagcagt tccccacagc
     2461 agcttcacgc cgctctcttc ttgcttgcct gccaggacat caaccatttg cgcaaaatta
     2521 ttgatgtact cttttaacga cgcgccctca ggggaaacat ccacatcgtg gaagcaataa
     2581 aatggcacat gtaacttgtg gaaaaactca aatgcgacat ctgctttacg cttcgccaac
     2641 gccagtgcct caccaggctg ctgccacgga cgattaaacg cccccacacc aaacatatcc
     2701 gccccgttcc agcagaaggt gtgccagtag caggcggcaa aacgcaagtg ctcttccata
     2761 cgcttgccca acaccagttc gtcgggattg tagtgacgga atgctaacgg gtttgaggat
     2821 tttgagcctt cataacgaac gcgatcgagc tggtcaaaat aggcttgcat attgaactcc
     2881 ataatcaggt aatgccgcgg gtgatggatg atgtcgtaat attgggcact ccctttcagt
     2941 tgctcaatta tgttatttca cactgctatt gagataattc acaagtgtgc gctcgctcgc
     3001 aaaataaaat gggatgatga aactgggtaa ttcctcgaag agaaaaatgc aataagtaca
     3061 attgcgcaac aaaagtaaga tctcggtcat aaatcaagaa ataaaccaaa aatcgtaatc
     3121 gaaagataaa aatctgtaat tgttttcccc tgtttagttg ctaaaaattg gttacgttta
     3181 tcgcggtgat tgttacttat taaagctgtc ctctaactac agaaggccct acaccatgaa
     3241 aataaagaac attctactca ccctttgcac ctcacttctg cttaccaacg ttgcggcaca
     3301 cgccaaagaa gtcaaaatag gtatggcgat tgatgatctc cgtcttgaac gctggcaaaa
     3361 agatcgagat atttttgtga aaaaagcaga atctctcggc gcgaaagtat ttgtacagtc
     3421 tgcaaatggc aatgaagaaa cacaaatgtc gcagattgaa aacatgatta accggggtgt
     3481 cgatgttctt gtcattattc cttataacgg tcaggtatta agtaacgttg taaaagaagc
     3541 caaacaagaa ggtattaaag tattagctta cgaccgtatg attaacgatg cggatatcga
     3601 tttttatatt tctttcgata acgaaaaagt cggtgaactg caggcaaaag ccctggtcga
     3661 tattgttccg caaggtaatt acttcctgat gggcggctcg ccggtagata acaacgccaa
     3721 gctgttccgc gccgggcaaa tgaaagtatt aaaaccttat gttgattccg gaaaaattaa
     3781 agtcgttggt gaccaatggg ttgatggctg gttaccggaa aacgcattga aaattatgga
     3841 aaacgcgcta accgccaata ataacaaaat tgatgctgta gttgcctcaa acgatgccac
     3901 cgcaggaggg gcaattcagg cattaagcgc gcaaggttta tcagggaaag tagcaatttc
     3961 cggccaggat gcggatcttg caggtattaa acgtattgct gccggtacgc aaactatgac
     4021 ggtgtataaa cctattacat tgttggcaaa tactgccgca gaaattgccg ttgagttggg
     4081 caatggtcag gagccaaaag cggataccac actgaataat ggcctgaaag atgttccctc
     4141 ccgcctgctg acaccgatcg atgtgaataa aaacaacatc aaagatacgg tagttaaaga
     4201 cggattccac aaagagagcg agctgtaagc gttacgcccc ggcgcggagc gggggcgtga
     4261 tttctctcca tgccgcgtta attaattggc ttaggtggag tcgttatgcc ttatctactt
     4321 gaaatgaaaa atattaccaa aaccttcggc agtgtgaagg cgattgataa cgtcagcttg
     4381 cggttgaatg ctggcgaaat cgtctcactc tgtggggaaa atgggtcagg taaatcaacg
     4441 ctgatgaaag tgctgtgtgg tatttatccc catggttcct acgaaggcga aattattttt
     4501 gcgggagaag agattcaggc gagtcacatc cgcgataccg aacgcaaagg tatcgccatt
     4561 attcaccagg aattggcgct ggtgaaagaa ctgaccgtgc tggaaaatat cttcctgggt
     4621 aacgaaataa cccataatgg cattatggat tatgacctga tgacgctacg ctgtcagaag
     4681 ctgctcgcac aggtcagttt atccatttca cctgataccc gcgttggcga tttaggactt
     4741 gggcaacaac aactggttga aattgccaag gcacttaata aacaggtgcg tttgttaatt
     4801 ctcgatgagc cgacagcctc attaactgag caggaaacgt cggttttact ggatattatt
     4861 cgcgatctac aacagcacgg tatcgcctgt atttatattt cgcacaaact caacgaagtc
     4921 aaagcgattt ccgatacgat ttgcgttatt cgcgacggtc aacacattgg tacgcgtgat
     4981 gctgctggaa tgagtgaaga cgatattatc accatgatgg tcgggcgaga gttaaccgcg
     5041 ctttacccta atgaaccaca taccaccgga gatgaaatat tacgtattga acatctgacg
     5101 gcatggcatc cggttaatcg tcatattaaa cgagttaatg atgtctcgtt ttccctgaaa
     5161 cgtggcgaaa tactgggtat cgccggactc gttggtgccg gacgtaccga gactattcag
     5221 tgcctgtttg gtgtgtggcc cggacaatgg gaagggaaaa tttatattga tggcaaacag
     5281 gtagatattc gtaactgtca gcaagccatc gcccagggga ttgcgatggt acccgaagac
     5341 agaaagcgcg acggcatcgt tccggtaatg gcggttggta aaaatattac cctcgccgca
     5401 ctcaaaaaat ttaccggtag tattagccag cttgatgacg cggcagagca aaaatgtatt
     5461 ctggaatcaa tccagcaact caaagttaaa acgtcgtccc ccgaccttgc tattggacgt
     5521 ttgagcggcg gcaatcaaca aaaagcgatc ctcgctcgct gtctgttact taacccgcgc
     5581 attctcattc ttgatgaacc caccaggggt atcgatattg gcgcgaaata cgagatctac
     5641 aaattaatta accaactcgt ccagcagggt attgccgtta ttgtcatctc ttccgaatta
     5701 cctgaagtgc tcggccttag cgatcgtgta ctggtgatgc atgaagggaa actaaaagcc
     5761 aacctgataa atcataacct gactcaggag caggtgatgg aagccgcatt gaggagcgaa
     5821 catcatgtcg aaaagcaatc cgtctgaagt gaaattagcc gtaccgacat ccggtggctt
     5881 ttccgggctg aaatcactga atttgcaggt cttcgtgatg attgcagcta tcatcgcaat
     5941 catgctgttc tttacctgga ccaccgatgg tgcctactta agcgcccgta acgtctccaa
     6001 cctgttacgc caaaccgcaa ttaccggcat cctcgcggta ggaatggtgt tcgtcataat
     6061 ttctgctgaa atcgaccttt ccgtcggctc aatgatgggg ctgttaggtg gcgtcgcggc
     6121 gatttgtgac gtctggctag gctggccttt gccacttacc atcattgtga cgttggttct
     6181 gggactgctt ctcggagcct ggaacggatg gtgggtcgcg taccgcaaag tcccttcatt
     6241 tattgtcacc ctcgcgggca tgttggcatt tcgtggcata ctcattggca tcaccaacgg
     6301 cacgactgtt tcccccacca gcgccgcgat gtcacaaatt gggcaaagct atctacctgc
     6361 cagcaccggc ttcatcattg gcgcgcttgg cttaatggct tttgttggct ggcaatggcg
     6421 cggaagaatg cgccgtcagg ctttgggttt gcagtctccg gcctctaccg cagtagtcgg
     6481 tcgccaggct ttaaccgcta tcatcgtatt aggcgcaatc tggctgttga atgattaccg
     6541 tggtgttccc actcctgttc tgctgctaac gttactgtta ttgggcggca tgtttatggc
     6601 aacgcggacg gcatttggac ggcgcattta tgccatcggc ggcaatctgg aagcggcacg
     6661 tctctccggg attaacgttg aacgcaccaa acttgccgtg ttcgctatta acggattaat
     6721 ggtagccatc gccggattaa tcctcagttc tcgactcggc gctggttcac cttctgcggg
     6781 aaatatcgcc gaactggacg caattgcagc atgtgtgatt ggcggcacca gtctggcagg
     6841 cggcgtcggg agcgtggccg gagcggtaat gggggcattc atcatggctt cgctggataa
     6901 cggcatgagt atgatggatg taccgacctt ctggcagtat atcgttaaag gtgcgattct
     6961 gttgctggca gtatggatgg actccgcaac caaacgccgt tcttgatttt gataaaaatt
     7021 ttctcaaagc cggtaacgta ttaccggttt tgagtttttg catgattcag caggaaaaga
     7081 accatgttta ctaaacgtca ccgcatcaca ttactgttca atgccaataa agcctatgac
     7141 cggcaggtag tagaaggcgt aggggaatat ttacaggcgt cacaatcgga atgggatatt
     7201 ttcattgaag aagatttccg cgcccgcatt gataaaatca aggactggtt aggagatggc
     7261 gtcattgccg acttcgacga caaacaaatc gagcaagcgc tggctgatgt cgacgtcccc
     7321 attgttgggg ttggtggctc gtatcacctt gccgaaagtt acccacccgt tcattacatt
     7381 gccaccgata actatgcgct ggttgaaagc gcatttttgc atttaaaaga gaaaggcgtt
     7441 aaccgctttg ctttttatgg tcttccggaa tcaagcggta aacgttgggc cactgaacgc
     7501 gaatatgcat ttcgtcagct tgtcgctgaa gaaaagtatc gcggagtggt ttatcagggg
     7561 ttagaaaccg cgccagagaa ctggcaacac gcgcaaaatc ggctggcaga ctggctacaa
     7621 acgctaccac cgcaaaccgg gattattgcc gttactgacg cccgggcgcg gcatattctg
     7681 caagtatgtg aacatctaca tattcccgta ccggaaaaat tatgcgtgat tggcatcgat
     7741 aacgaagaac tgacccgcta tctgtcgcgt gtcgcccttt cttcggtcgc tcagggcgcg
     7801 cggcaaatgg gctatcaggc ggcaaaactg ttgcatcgat tattagataa agaagaaatg
     7861 ccgctacagc ggattttggt cccaccagtt cgcgtcattg aacggcgctc aacagattac
     7921 cgctcgctga ccgatcccgc cgttattcag gctatgcatt acattcgtaa tcacgcctgt
     7981 aaagggatta aagtggatca ggtactggat gcggtgggca tatcacgctc caatcttgag
     8041 aagcgtttta aagaagaggt gggtgaaacc atccatgcca tgattcatgc cgaaaagctg
     8101 gagaaagcgc gcagtctgct gatttcaacc accttgtcga tcaatgagat atcgcaaatg
     8161 tgcggttatc catcgctgca atatttctac tctgttttta aaaaagcata tgacacgacg
     8221 ccaaaagagt atcgcgatgt aaatagcgag gtcatgttgt agcgatgatg agaattgtcg
     8281 gcgtcgcttc aggtaactca gcacaaccac ctgatgggag caaaagcctt atccgactga
     8341 caagtcggat aaggctcgag gaaatgcaat tacatatgcg ccgcgattaa ccgttggtta
     8401 tcctggtaca ttgcaaacag gtagttgtta taactcttcc ctttggtcga gtagcccttc
     8461 agcttgtgaa tcatcgctgt ggcagtcact tcctgatccg ctttacgcag ctgtgcacgc
     8521 gatttacgga acgaagagta agccgggtgc gtattgaggt ttgtaacata ggcgctcacc
     8581 gattctttaa cagaactaaa ctgtgagtac cctttcactt tacccggcgc attggtacaa
     8641 cgtcctttca tgcatttcat gccgaaaaga ttgttgttgt tgcgcgccag ctttgacgtt
     8701 ccccaaccgc tttctgctgc agccatcgtc gccaccatac tggtagggat aatgtctacg
     8761 cgttcaagca aggtattcca cgggattttt cgcgtattac cagaccactt caccttgtag
     8821 cgtttggcga tgtctttcag acgcgcacgc tcagcaggtg accattggcc ctgatactgt
     8881 tttgaaatca gccagttacg ttccgcagta atggccgcat tttggctggt aatgtaaggc
     8941 attacagtcc ggagaaacgc ctttttcctt ggtgttccgg aagggtattt tcgcaaatca
     9001 ggaagtgaac tactctttgc actattgcga gaatactctt gtttactgct tacctgttta
     9061 ttactagctt tagttaagtg ggacttttga ctcgctgttg ttgtgtgcgt cttcgctaac
     9121 acctcactcg aaaacaccag agtgagtaac ataagaatca tcgccccata tcgtcgtatg
     9181 ggagtcaaaa tcatcaggtc tcctggtcgg atttaatcat tccaacacct tatatttttt
     9241 acaaatttga gagttgaatc tcaaatcata tcaaaaatag ctgtcaagag caccccaagg
     9301 aatagtccaa atctgaaact atgtcacgag ttaacgattc agattggcgc taaatcgcag
     9361 aaaatgtggg gtttatcgca aaattcagcc gttttttgcg cgcgatcgct cacccttgct
     9421 tctcatcctg tggagttacc gctcagggat gagttttgtc tggcttatcg ctggcaaact
     9481 gtctgaaatc gcagcaataa ggactcatcc gccatgaaac tcgccgcctg ttttctgaca
     9541 ctccttcctg gcttcgccgt tgccgccagc tggacttctc cggggtttcc cgcctttagc
     9601 gaacagggga cgggaacatt tgtcagccac gcacagttgc ccaaaggtac gcgtccacta
     9661 acgctaaatt ttgaccaaca gtgctggcag cctgcggatg cgataaaact caatcagatg
     9721 ctttccctgc aaccttgtag caacacgccg cctcaatggc gattgttcag ggacggcgaa
     9781 tatacgctgc aactagacac ccgatccggt acaccaacat tgatgatttc catccagaac
     9841 gccgtcgaac cggtagcaag cctggtccgt gaatgcccga aatgggatgg attaccgctc
     9901 acactggatg tcagcgccac ttttgcggag ggagccgcag tccgggatta ttacagccag
     9961 caaattgcga tagtgaagaa cggtcaaata acgttacaac ccgctgccac cagcaacggt
    10021 ttactcctgc tggaacgggc agaaactgac acatccgccc ctttcgactg gcataacgcc
    10081 acggtttact ttgtgctgac agatcgtttc gaaaacggcg atcccagtaa tgaccagagt
    10141 tacggacgtc ataaagacgg tatggcggaa attggcactt ttcacggcgg cgatttacgc
    10201 ggcctgacca acaaactgga ttacctccag caactgggcg tcaatgcttt atggataagt
    10261 gccccatttg agcaaattca cggctgggtc ggcggcggta caaaaggtga tttcccgcat
    10321 tatgcctatc atggttatta cacacaggac tggacgaatc ttgatgccaa tatgggcagt
    10381 gaagccgatc tacggacgct ggttgatagc gcgcatcagc gcggtattcg tattctcttt
    10441 gatgtcgtga tgaaccacac tggctatgcc acgctggcgg atatgcagga gtatcagttt
    10501 ggcgcgttat atctttctgg tgacgaagtg aaaaaaacgc tgggtgaacg ctggaacgac
    10561 tggaaacctg ccgccgggca aacctggcat agctttaacg attacattaa tttcagcgac
    10621 aaaacaggct gggataaatg gtggggaaaa aactggatca gaacggatat cggcgattac
    10681 gacaatcctg gattcgacga tctcactatg tcgctggcct ttttgccgga tatcaaaacc
    10741 gaatcaacta ccgcttctgg tctgccagtg ttctataaaa acaaaacgga tacccacgct
    10801 aaaatcatcg acggctttac ccctcgcgat tacttaaccc actggttaag tcagtgggtc
    10861 cgcgactatg ggattgatgg ttttcgggtc gataccgcca aacatgttga gttgcccgcc
    10921 tggcagcaac tgaaaaccga agccagcgct gcacttcacg aatggaaaaa agctaacccc
    10981 gacaaagcat tagatgacaa acctttctgg atgaccggtg aagcctgggg ccacggcgtg
    11041 atgcaaagtg actactatcg ccacggcttc gatgcgatga tcaatttcga ttatcaggag
    11101 caggcggcga aagctgtcga ttgtctggcg cagatggata cgacctggca gcaaatggcg
    11161 gagaaattgc aggatttcaa cgtgttgagc tacctctcgt cgcatgatac ccgcctgttc
    11221 cgtgaagggg gcgacaaagc agcagagtta ttattattag caccaggcgc ggtacaaatt
    11281 ttttatggcg atgaatcctc gcgtccgttc ggtcctaccg gttctgatcc gctgcaaggt
    11341 acgcgttcgg atatgaactg gcaggatgtt agcggtaaat ctgccgccag cgtcgcgcac
    11401 tggcagaaaa tcagccagtt ccgcgcccgc catcccgcaa ttggcgcggg caaacaaacg
    11461 acactttcgc tgaagcaggg ctacggcttt gttcgtgagc atggcgacga taaagtgctg
    11521 gtcatctggg cggggcaaca gtgacttttc cggcttcccg ttcgtgagta cctcgggaag
    11581 ccgccaacca ggataaaatg tcagccctaa tcagcattgc aggataaagc cccgctcact
    11641 cttcaacaga ccgatttgca ccccagcaaa tgtagcgtta ttgttacctt ccttgctaca
    11701 gagttcgaca gatatcccgc tatgacattc tccctttttg gtgacaaatt tacccgccac
    11761 tccggcatta cgctgctgat ggaagatctg aacgacggtt tacgcacgcc tggcgcgatt
    11821 atgctcggcg gcggtaatcc ggcgcagatc ccggaaatgc aggactactt ccagacgcta
    11881 ctgaccgaca tgctggaaag tggcaaagcg actgatgcac tgtgcaatta cgacggtcca
    11941 caggggaaaa cggagctact cacactgctt gccggaatgc tgcgcgagaa gttgggctgg
    12001 gatatcgaac cacagaatat tgcactaaca aacggcagcc agagcgcgtt tttctactta
    12061 tttaatctgt ttgccggacg ccgtgccgat ggtcgggtca aaaaagtgct gttcccgctg
    12121 gcaccggaat acattggcta cgctgacgcc ggactggaag aagatctgtt tgtctctgcg
    12181 cgtccgaata ttgaactgct gccggaaggc cagtttaaat accacgtcga ttttgagcat
    12241 ctacatattg gcgaagaaac cgggatgatt tgcgtctccc ggccgacgaa tccaacaggc
    12301 aatgtgatta ctgacgaaga gttgctgaag cttgacgcgc tggcgaatca acacggcatt
    12361 ccgctggtga ttgataacgc ttatggcgtc ccgttcccgg gtatcatctt cagcgaagcg
    12421 cgcccgctat ggaatccgaa tatcgtgctg tgcatgagtc tttccaagct ggggctacct
    12481 ggctcccgct gcggcattat catcgccaat gaaaaaatca tcaccgccat caccaatatg
    12541 aacggcatta tcagcctggc acctggcggt attggtccgg cgatgatgtg tgaaatgatt
    12601 aagcgtaacg atctgctgcg cctgtctgaa acagtcatca aaccgtttta ctaccagcgt
    12661 gttcaggaaa ctatcgccat cattcgccgc tatttaccgg aagatcgctg cctgattcat
    12721 aaaccggaag gagccatttt cctctggcta tggtttaagg atttgcccat tacgaccgag
    12781 cagctctacc agcgcctgaa agcacgcggc gtgctgatgg tgccggggca caacttcttc
    12841 ccgggactgg ataaaccgtg gccgcatacg catcaatgta tgcgcatgaa ctacgtacca
    12901 gagccggaga aaattgaggc gggtgtgaag attctggcgg aagagataga aagagcctgg
    12961 gctgaaagcc attaatacgc tattccggcg ttgagaaacg ccggaaaaac gtttcaaaca
    13021 ggctgctgcc gtagccgatg ccgctgcact ttctcgacat ccatgcactg caacgccttt
    13081 gtcgggcagg cttcaacaca ggccggcccc gtcgcccgat gccagcacag atcgcactta
    13141 atcgccctcg cctttttgcg cgaagaaacg acctccatcg caccaaacgg gcaagccagc
    13201 atacagcttt tacagccaat gcaacgtgat tgttcaacga aaatatgccc atgttcgcgg
    13261 cttatcgcgt caacagggca gacattcgcg cacggtgcat cttcacactg atgacaggct
    13321 actgccgtgg tccagctgtg gtctttaatg acacgaatac gggaaataaa ctcgtctggt
    13381 gacaacgcag cgcaatcctg attctcctga tgcgacactg cgcaagccac ttcacaggta
    13441 cggcaaccga tacatttcgt cgcatccgca ataataaacc ggttcatgat cactcctttg
    13501 cactaaaaca gcagagtgcc agagagcgcg tccctactgc tttgatccaa cgaaggaaat
    13561 gttaaagttt tggcacttgt ccaaagggtt atgtaatcgc gccctggtcg tccctgacag
    13621 taaatcccag ctcattagaa atagcctgcg cggtttcacg cagtggtttc aggagatttt
    13681 tctctcccac ctgtttcaga cgtgatgtcg aaagcgaaat cgacacggcg tacggcaccc
    13741 gcccatgaat atcaaacacc ggaacagcaa tacaggagac gccgagttcg ttttcttctc
    13801 tgtccatcgc cgctccactt tcacgaatgt gcgccagttc gtcgaacatc gcgggcagct
    13861 cggtaatggt attgcgggtt aacggctgga tctcatgctg atggctttcc cagtatgact
    13921 tcacgtagtc cgggtgacca aacgccatgt agatcttgcc cattgcggaa cagtagagcg
    13981 gcatatgctg gcctatatag gcacgggttc gcagcatccc ggttgtgggt tccagcttat
    14041 aaatcaaaat agcgtgatcg tcttcgcggc tggagaagtt aatggtttca ccagtggcga
    14101 tgttcagtgc ctcaagatgc ggagcggcga tatgaatgat attcagcgaa gatagcgcct
    14161 tctgcccgac ggcaataaat ttggtggtca ggcgataact ccctgcggcg ggcgcggtgg
    14221 tcacatagcc gcaggactgt aatccctgca ataagcgatg gacggtactc ttatttaaac
    14281 cagccagctc cgaaagatgc gccaacggac aaccgtttgg atagttgctc aaaatctcaa
    14341 tcagcatcaa cccacgaaac agactctggc ttccggctgg acgctctttt tcctgcgcca
    14401 tctcgttctc tttttttccc atcacttctt tccccatttt gtcgcgtcct gatggtagcg
    14461 caaagtgtgc cgtagttcac gatctcgaca gataatttat aaccacttga tttttaagtt
    14521 ttttgaaatt catcaatcag attgctttgt taaaaagtga tcgatatatt tgaaatcaag
    14581 tttcgtatat tgaaatttta agccaaaaaa gcgatcaaaa aaacaaggaa gcctgggatg
    14641 aaagtgacat ttgagcagtt aaaagcagcc tttaatcggg tcttaatttc acgcggcgtt
    14701 gacagcgaaa cggctgacgc ctgtgcagag atgttcgccc gcaccaccga atccggcgtt
    14761 tattctcacg gcgttaatcg tttccctcgt ttcattcaac aactggaaaa cggcgatatc
    14821 attcctgatg cccaacccaa acgtataacc agcctcggcg caattgaaca gtgggacgcc
    14881 cagcgttcga tcggtaacct gacagcgaaa aagatgatgg atcgcgccat tgaactggct
    14941 gccgatcacg gtattggtct ggtggcacta cgtaatgcca accactggat gtgcggcggc
    15001 agctacggct ggcaggcggc ggaaaaaggc tacattggca tttgctggac caactccatc
    15061 gccgtaatgc caccgtgggg cgcaaaagag tgtcgcatcg gcaccaaccc gctgatcgtc
    15121 gccattcctt ccacgccgat caccatggtc gatatgtcga tgtcgatgtt ctcttacggc
    15181 atgttagaag ttaatcgcct ggctggtcgt cagctcccgg tagatggtgg ctttgatgat
    15241 gagggcaatt tgaccaaaga acctggcgtt atcgagaaaa atcgccgcat tttgccgatg
    15301 ggctactgga aaggttcggg catgtcgatt gtgctggata tgatcgctac cctcctttct
    15361 gacggcgcat cggttgccga agtcaccgag gacaacagcg acgaatacgg catttcacaa
    15421 atttttattg ccattgaagt ggacaagctt atcgacggtc ccacccgcga tgccaaactg
    15481 caacgcatta tggattacgt taccagtgcc gagcgtgctg acgaaaatca ggccattcgc
    15541 ttacccggcc acgaatttac taccctgctg gcagaaaacc gccgtaacgg tattaccgtt
    15601 gatgacagcg tgtgggcaaa aatccaggcg ttataaggag ataagccatg atttttggac
    15661 atatcgcgca gcctaatccg tgccgtttgc ccgccgccat tgaaaaggcg ctcgattttc
    15721 tgcgcaccac cgacttcaac gccctggatc cgggcgttgt cgaaatcgac ggcaagaata
    15781 tttatgcgca aattatcgat ttaaccacac gcgaagcggt ggaaaaccgt ccggaagtgc
    15841 atcgtcggta tatcgatatt cagtttctgg cgtggggtga agagaaaatt ggcattgcca
    15901 ttgatacggg aaacaataaa gtcagcgaat cactattaga gcagcgcgat attatttttt
    15961 atcacgatag tgaacatgaa tcatttatag aaatgatacc gggtagttac gctattttct
    16021 tcccgcagga tgtacatcgc ccggcatgta ataaaaatgc cactacggca atacgcaaga
    16081 tcgtggttaa agtggccctc gctgctttat aaaaaatgat tactggagca cataatgaaa
    16141 acgaataatg ccggttatat tatcggcgcg tatccctgtg caccttcttt tcaccaaaga
    16201 agtgaagagg aagagaagga tttctggcga caattatctg agactccaga cattttgggt
    16261 ctggaacaac cttgcctgga aaattttcac cctcttggcg atcaatggtt actccgtcat
    16321 acgccagaga gctggaaatt tgtcgtcacc gcagtgatgg aaaccatgcg tcgccgcagc
    16381 gaaaacagcg ggtttggtct cgcctccagt gatgaagaac agcgccaggc ctgcgtggcg
    16441 tactatcgcc acctgttcaa taaaatcaac gcattgcagg ctaataaagt gctcgcactg
    16501 gcgctccagg ctgcaccgtt agcaacgaat cctaatgtta tgcaagcgac ggacgctttt
    16561 gcccgctcat tgaaagaaat cgccagttgg gactggccgt gcaagctggt gctggaacac
    16621 tgcgacgcca tgacatcttc ttccccccga aaaggctttt tgcctttaga aaatgtgctg
    16681 gaagttatta ccgattatga catcagcatc tgtatcaact gggcgcgctc tgccattgaa
    16741 gggcgcaata caacgctgcc gctgacccac acccaaatgg cgaaacaagc cggaaaactc
    16801 ggcgcgttga tgttctctgg tacgacgcta aacggggcat acggcgaatg gcaggattta
    16861 cacgcaccgt ttgcaccatt ctgcgcagaa agcctgatga ccacagatca tgttcgcgag
    16921 ttatttaatg tagcagaatc gtcaacattg cattttgctg gcatcaagct actggaaata
    16981 aatgcgacgg ctgatgtgca ccatcgcatc gaaatattac gtaacggcat tcactctctg
    17041 aatgaatctc gttaaataga tccgcttata tatcactttg aatatctaat tagccgtttt
    17101 ctgataatta ttacgaatat taacaacatt agcgcataaa aaatattgca taaccagaag
    17161 gactcgttat gaaacggata ctcgaaggca ttcttgcgat catcatcgca atactgtctt
    17221 gtattatttt tattaatatc attcttcgat atggattcca cacaagtata ttatcgattg
    17281 atgaattatc ccgactttta tttgtctggt taacctttat tggcgcaatc gttgcttata
    17341 tggacaacag ccatgtgcag gttacttttt tagtcgaaaa actctcaccg gctaatcaac
    17401 aacgtgtttc gctgctaacc catacgctca ttttattgct gtgtctgggg ctggcctggg
    17461 gcgctataga aaaaacagcg caagactgga gcaacttatc gcccattctt ggcgtccccg
    17521 ttggcttaat gtacgccgcc gctatcccca ccagtctgat tatcgcattg ctggaattgc
    17581 gtcacttata ccggcagttc acaaataccc ccagccgaaa ccaacaagga gcctgacgat
    17641 gacaatcctt atatttattg tcagtttgtt aggggctatc gcaattggtg ttcccatcgc
    17701 ctgggcatta ttgttgtgcg gcatctcatt gatgttctgg atggatatct ttgatgtgca
    17761 aattctggca caaacgttgg taaatggcgc agacagcttc tccctgttag ccatcccctt
    17821 ctttgtactg gcgggtgaga tcatgaacgc gggcggcctg tcgcaacgta tcgtcgactt
    17881 gccaatgaaa ctggtaggcc acaggccagg cggtctgggt tacgtgggcg tgctggcagc
    17941 gatgatcatg gcaagcctgt ccggttctgc ggttgctgat accgcagctg tcgcggcgct
    18001 gctggtgccg atgatgcgcc aggccaacta tccggtaaac cgcgccgccg ggcttatcgg
    18061 ttccggcggg attattgcgg ccattatccc accttccata ccactcatta tcttcggcgt
    18121 ctccagcgga ctctccatca gtaagctgtt tatggcgggc atcgcaccgg gcatcatgat
    18181 gggcgtcacg ctgatggtta cctggtggtg gcaggcaaaa cgactgaatt taccttgtca
    18241 gccgaaagcc tcactgcgag aagtctggca atccttagtt tccggtattt gggcgctctt
    18301 tttaccgata attattattg gcggtttccg ttcggggtta tttacaccga ccgaagcagg
    18361 cgcggttgcc gccttctacg ctctgttcgt ctcggtggtg gtctatcgcg agatgacctt
    18421 ctccacgctt tatcatgtgc tgattaacgc ggcaaaaacc acatccgtgg tgatgttcct
    18481 ggtggcctct gctgcggtat ctgcatggct tattacgatc gccgaattac ccatgatggt
    18541 atcggagcta ttacaaccgt tggttgattc gcctcgctta ttattcatcg tcattatgct
    18601 cgctattatg gtgatcagta cggtcatgga cttaacgcct accgtattaa ttcttacacc
    18661 agtattaatg ccattagtga aagaagcggg aatagatccg gtctatttcg gcatcatgtt
    18721 tattatcaac tgttcaatat cactgattac gcctccagtc ggtaatgttc ttaacgtggt
    18781 atgcggcgtg gcgaaactta aatttgacga tgcggtaaaa ggcgttgcgc cttacgtcat
    18841 ggttttattc atgttgttag cattatttat ttttataccg gagctcatta ccgctcctct
    18901 taaatggatg agttaaaagg aaatcataat gaaattacgt tctgtaacct acgctttatt
    18961 aattgccgga gtggcgacgt tcagcacatc ttctctggcg gcacaatcat tacgtttcgg
    19021 ttatgaaacc tcacaaaccg attcacaaca tattgcggcg aaaaaattta atgaattact
    19081 gcaggaaaaa accaaaggcg aactgaaatt aaaactgttc ccggatagca cccttggtaa
    19141 tgcgcaggcg atgatcagcg gcgtgcgtgg cggcactatt gatatggaga tgtctggctc
    19201 taacaacttt acgggactct cgcccgtcat caacctgctc gatgtcccgt tcctgttccg
    19261 cgataccgct cacgcgcata aaacgctcga cggcaaagtc ggtgatgacc tgaaagtctc
    19321 ccttgaaggt aaagggctga aagtgctggc ttactgggaa aacggctggc gcgatgtcac
    19381 caactcacgc cagccagtta aaacacctgc cgacctgaaa ggactaaaaa tccgcaccaa
    19441 caacagcccg atgaatatcg ccgcatttaa agtttttggc gctaacccga tcccgatgcc
    19501 gtttgccgaa gtctataccg ggctggaaac ccgcactatc gacgctcagg aacacccgat
    19561 caacgtcgtc tggtcagcaa aatttttcga agtgcagaag tacctttctc tgacccatca
    19621 cgcctattcc ccacttctgg tggtgatcaa caaagcgaag tttgatggct taaccccgga
    19681 gttccagcag gcactgatct catctgcgca ggaagcgggt agctatcagc gcaaactggt
    19741 cgccgaagat cagcaaaaaa tcatcgacgg tatgaaagaa gcgggcgtgg aagtcatcac
    19801 cgatctcgac cgcaaagcct ttagcgatgc gctgggtacc caggtccgtg acatgtttgt
    19861 taaagatgtt ccccagggtg ctgatctgct gaaagccgtg gatgaggtgc aataaaccat
    19921 gacgcaatac tggctggggt tagattgtgg cggtagctgg ctgaaagccg ggctgtatga
    19981 ccgagaaggc cgggaggcgg gcgtgcagcg cctgccgctg tgcgcattaa gtccacagcc
    20041 aggctgggca gagcgcgaca tggcagaact gtggcaatgt tgcactgctg tcattcgctc
    20101 cctgcttacc cattctggcg tcagcgggga acaaattgtc ggtatcggca tctccgcgca
    20161 gggaaagggc ttatttctac ttgataaaaa cgacaaaccg ctcggtaacg ccattttgtc
    20221 ctcggatcgc cgggcgatgg aaatcgttcg tcgctggcag gaagatggca tcccggaaaa
    20281 actctatccg ctgacccgac aaaccttatg gaccgggcat ccggtgtcgc tgttacgctg
    20341 gctgaaagag cacgaaccag aacgctacgc gcaaattggc tgcgtgatga tgacgcacga
    20401 ctacctgcgc tggtgtttaa ccggcgtcaa aggttgcgaa gagagcaata tttctgagtc
    20461 caatctctac aacatgagtc gcggggaata tgacccgtgc ctaaccgact ggctggggat
    20521 cgctgaaatc aatcacgccc tgccgcctgt tgtcggatct gccgaaatct gcggggaaat
    20581 caccgctcag acagccgtac tgactggtct gaaagcgggt acccccgttg tcggcggcct
    20641 gtttgatgtg gtttccaccg cactctgcgc cgggctcgaa gacgaattca ccctcaatgc
    20701 ggtgatgggg acctgggcgg tgaccagcgg cataacccac ggtttacgtg acggtgaagc
    20761 gcatccgtat gtctatggtc gctacgttaa cgatggtcaa tttatcgttc acgaagccag
    20821 ccccacctct tccggcaatc tcgaatggtt taccgcacag tggggagaaa tctcatttgc
    20881 tgagattaat caggccgtag ccagtttgcc gaaagccggt ggcgctctct ttttcctgcc
    20941 gttcctgtac ggcagcaacg ccggactcga aatgaccagc ggtttctacg ggatgcaggc
    21001 cattcacacc cgtgcacacc tcttacaggc tatctatgaa ggggtggtgt tcagccatat
    21061 gacccatctc aaccggatgc gcgaacgttt tactgatgtg cacaccctgc gcgtcactgg
    21121 cggcccggcg cactccgatg tctggatgca aatgctggct gacgtcagcg gtctgcgtat
    21181 cgagctgccg caggtggaag aaaccggctg ctttggtgcg gcacttgccg cccgcgtcgg
    21241 taccagggtt tatcgcgatt tcagcgaagc ccaacgtgac ttacagcacc cggtacgcac
    21301 cctgctgccg gatatggccg cccatcagct ttaccaacaa aaataccaac gctatcaaca
    21361 tctcattgcc gcacttcagg gttatcacgc ccgcatcaag gagcacacat tatgagtcga
    21421 ccacttctgc aactggccct cgaccactca tcacttgaag ccgcgcagcg cgacgtgacg
    21481 ctgttaaaag acagcgtcga tattgtcgaa gcaggcacca ttctctgttt aaacgaaggg
    21541 cttggcgcag tgaaagcctt gcgcgaacag tgcccggaca aaatcatcgt tgccgactgg
    21601 aaggtcgccg acgcgggtga aacgctcgcg caacaggcat ttggcgcagg cgctaactgg
    21661 atgaccatca tctgcgccgc gccgctcgcc acggtggaaa aaggccacgc gatggcacag
    21721 aactgcggcg gtgaaattca gatcgagcta ttcggcaact ggacgctgga cgatgcccgt
    21781 gactggcatc gtattggtgt acgacaggcg atttatcatc gtggtcgtga cgcgcaggcc
    21841 agcgggcaac agtggggcga ggccgatctg gcacgcatga aggcgctttc cgatatcggc
    21901 cttgagcttt ccattaccgg cgggattacc cctgctgacc tgccgctgtt taaagagatc
    21961 cgcgtgaaag cgtttattgc cggacggtcg ctggcaggcg cagcaaatcc ggcgcaagtg
    22021 gccgctgatt ttcatgcgca aatcgactcc atctggggag gcaagcgtgc gtaatcatcc
    22081 gttaggtatt tatgaaaaag cgctggcgaa agatctctcc tggccggagc ggctggtgct
    22141 ggcaaaaagc tgtggttttg attttgtcga aatgtcggtg gatgaaaccg acgaacggtt
    22201 gtcacgtctt gactggagcg ccgcacaacg tgcttcgctg gtcactgcga tgctcgaaac
    22261 gggtgttgct attccgtcaa tgtgcctgtc cgcacatcgt cgttttcctt ttggtagccg
    22321 ggacgacgcc gtgcgccagc gggcgcggga gattatgagt aaagcgattc gcctggcacg
    22381 cgatctcggc attcgtacta ttcaactggc aggttacgac gtctattacg aagatcatga
    22441 cgaaggcacc cagcaacggt ttgctgaagg gctggcgtgg gcggttgaac aggcagcggc
    22501 atcacaagtc atgctggcgg tggagattat ggacaccgcg tttatgaact ctatcagcaa
    22561 atggaaaaag tgggacgaaa tgcttgcgtc accgtggttc accgtttacc cggacgtcgg
    22621 caatctcagc gcctggggca atgatgttcc cgccgaactg aaactgggca tcgaccgtat
    22681 cgccgccatc cacctgaaag acactcaacc cgttaccgaa catagccccg gacagttccg
    22741 cgatgtgccg tttggcgaag gctgtgtcga ttttgttggc atcttcaaaa cgctgcatga
    22801 gctgaactat cgcggttctt tcctgattga gatgtggacc gaaaaagcca aagagccggt
    22861 gctggagatt attcaggcgc ggcgctggat tgaagcgcgt atgcaggagg ccggatttat
    22921 atgttagagc aactgaaagc tgacgtgctg gcggcaaacc tggcgcttcc cgttcatcat
    22981 ctggtgacgt tcacctgggg caatgtcagc gcgatagacg aaacgcggca atggatggtg
    23041 attaagcctt ccggcgttga gtatgaggta atgaccgccg acgatatggt ggtggttgag
    23101 atagccagcg gcaaggtggt ggaaggcagc aaaaagccct cttccgacac gccaacgcat
    23161 ctggcgcttt accgtcgctt tgcggagatt ggcggcatag tgcataccca ctcgcgccac
    23221 gccaccatct ggtcgcaggc cggacttgat ctccccgcct ggggcactac tcacgccgat
    23281 tatttttacg gagccatccc ctgcacgcgc ctgatgaccg cagaagagat caacggtgag
    23341 tatgaatacc agaccggcga agtgatcatt aaaaccttcg aagagcgtgg gttgaacccg
    23401 gcacaaatcc cggcggtact ggtgcattct cacggcccgt tcgcctgggg aaaaaatgcc
    23461 gccgatgcgg tgcataacgc cgtggtactg gaagagtgcg cctatatggg tctgttctcg
    23521 cgccagcttg cgccacagct ccctgcgatg caaaacgaac tgctggataa gcactacctg
    23581 cgtaagcatg gggccaatgc ctattacggg cagtaatccc tcacgccggg gcttcatcgc
    23641 cccggcacta cgaattgata tgttccttgc tgtaacgccg cttccacgct gctggcgtta
    23701 agccggtgtg tttgcgaaaa atctgccgga aatagccgac gtcattaaac ccgcacaacg
    23761 ccgccacttc cgtgagcgat cgcgcttcgc taattaacag cttttcggct tcgcgcaccc
    23821 gctggcggtg gattgcttct gttaacgtca gatgaaacac ccgccgatag acgcgcccaa
    23881 gataatcggc attgcagtac agctcgcggg ctaaaagcgc cgtggaaagc gggcggtgat
    23941 attgcgtgcg aatcagtttc tgcgctttcc aggcaagggt ggtgcctgca ccatcggcct
    24001 gttcatcaag acgcgcgtca cgggtgagct gctgcaaaat cagcagcaca ataaactcca
    24061 gcgccggagt gcgttgatgc ttttcctgtt cgcttaagaa ctggcgaaac aaggccacca
    24121 gcacctgcgg atcggcaacc ttagtttgtt gcggcacgct aagatgagtg agccagcgcg
    24181 gatcgttgtc cggcgcttta acctcaaaat gcagccagta aaatttgaga tcggcgggaa
    24241 aatcctccac cccaacatgc tgtcggttcg gccagagtaa taaactctct cccgcatcga
    24301 ccagaaatat ccgttcatct tcctgaatcg ttaatcgacc tttttcgacg aagataattt
    24361 cccatgactc cagccgcctt gcaggatgcc tccctacgcc acgggaaata aataatccac
    24421 cattttgcac tttaatcggt aacgtcatgg ataattcgag cattgatatg taatttcccg
    24481 cttattcatt aatgattaaa cacattacct tttgattatt aatcaaaaac attaatttca
    24541 cctgatccat ttcacacttt taaattcagg tcggaatcgt cacctttttt tactcttttc
    24601 tcgccttgtt gatattcccg ttcacggcag aattaatcag gtcattgcaa taaaactaaa
    24661 aattgctccc tattcacgag gaatatctat gacctctaca ccgattacca ccgctgatat
    24721 cgctaaaggt aaaattgacg atgcgttatc tgtacgggaa aaaataggct acggcctggg
    24781 tgacgcaggc ggcaccgtaa taacttgcct gatcatgaac tttctcacct ttttctacac
    24841 cgacgttttt ggcttaactc cggcgctggt tggcacgctg tttattgcgc tacgcgtgtt
    24901 tgatgccatc tccgacccgg tgatgggcgt cattgccgac cggacgcaaa gtcgctgggg
    24961 gcgctttcgt ccgtggcagt tatggattgc cattcccatc ggcattatcg gcatcctgac
    25021 attcaccgtg ccagatgcca gcatgggagt aaaaatcgcc tgggcgttcg gtacttacct
    25081 gctcctttca gtcggttata cagccatcaa cgtaccgtac tgcgcgctga tcaacaccat
    25141 gaccacccgc cacaatgaag tgatctcctg ccagtcctgg cgattcgttc tctgcggcgt
    25201 agcgggattt ctggtttcgg taggcttacc gtggatggta gatctcttcg gtcagggcaa
    25261 cgctgcacgc ggctatcaac ttggcgtcgg cgtattgtgc gccattgccg tggtgatgtt
    25321 cctgtgctgt ttcttctggg ttcgtgaacg ggtgccactc tccacaatgg ggaaatttac
    25381 cctgcgcgaa catcttgccg ggctgcggaa caacgaccaa ctgctgctga tgctggtcat
    25441 gtctttcctg ctgattaacg tctttaatat tcgcggcggt gggtatatgt acttcattac
    25501 ctacgtctta caaggcagta cgggctacac gtcgctgttc ttcaccatgg tcaccttcgc
    25561 ctccattatc ggctcggtga ttgtcagccc attaacgcgg cgtttcgata ccgtcaaaat
    25621 ttactactac accaacctgc tcctcgctgc actggcggtg ttgatgtggt tcctgccctc
    25681 cagcccggct tatcaaacgc tgtggctggt ggtgatcctc ggtaatggcg tgattcttgg
    25741 cttcacattg ccactgcact tctcattgat ggcctttgcc gatgactacg gcgagtggaa
    25801 aacccgcgta cgttcttccg gcatgaactt cgccttcaat ctgtttttca tcaagctggc
    25861 ctgggcctcc agcgccggga tcatcagcct gctgtttatt tttgtcgcct accagccagg
    25921 cgtggaaaac cagaccgcca gttcgcttgg cgggatcgcg gcgatggaaa cattgctgcc
    25981 tgcgctgttc cacctgctgc tggcgatggc gatccgcttt tgcaaactca ataaccctat
    26041 gatgtcacgc attgctagcg acctgcgtca gcgtcatgta cagccttaag gagcacaaga
    26101 tgaacatttc ggaagtcgat ctgcataaac tgacggtcag cgatccgttc ctcggtcagt
    26161 accaacaact ggtccgcgac gtggtgattc cttatcagtg ggatgccttg aacgatcgta
    26221 tcccagaagc ggaacccagc catgcgattg aaaactttcg cattgccgcc ggacttcagg
    26281 agggtgaatt ttacgggatg gtgtttcagg acagcgacgt cgccaaatgg ctggaagcgg
    26341 tagcctggtc gctgtgccag aagccggacg ccgaactgga aaaaaccgcc gacgaggtga
    26401 ttgaactgat cgcttccgcc cagtgcgaag atggctatct caatacttac tttacggtaa
    26461 aagcgcccga agaacgctgg agcaatctgg cggagtgtca tgaactttac tgcgccggtc
    26521 atctgattga agccggagtc gccttcttcc aggctacggg caagcggcgc ttgctggaag
    26581 tggtttgccg tctgaccgat catatcgaca gcgtatttgg tccagatgaa agtaagttac
    26641 atggttatcc tggtcacccg gaaattgaac tggcactaat gcgcctgtat gaagtgaccg
    26701 aagagccgcg ctacctggcg ctgacgaact attttgtcga acagcgtggt gcgcaaccgc
    26761 actattacga ccaggaatat gaaaagcgcg ggcagacctc gcactggcac acctacggcc
    26821 cggcgtggat ggtgaaagac aaagcctaca gccaggcaca tttgcccatc gcacagcagc
    26881 aaaccgccat tggtcacgcg gtacgttttg tctacctgat gaccggcgtc gcgcatctcg
    26941 cgcgtttaag tcacgatgaa agcaagcgtc aggactgcct gcggctgtgg aacaatatgg
    27001 cccagcgtca gttatatatt accggcggca ttggctcaca gagcagcggt gaagcgttca
    27061 gcagcgatta cgatctgccg aatgacacgg tatacgctga aagttgcgcc tccatcggcc
    27121 tgatgatgtt tgcccgacga atgctggaaa tggaaggcga cagtcaatat gccgatgtga
    27181 tggagcgcgc actgtacaac accgtgctcg gcggcatggc gctggatggc aaacatttct
    27241 tctatgtgaa tccgctggaa gtacatccaa aatcgctgaa attcaaccat atctacgatc
    27301 acgttaagcc gatccgccag cgttggtttg gctgcgcttg ttgtccgcca aatatcgccc
    27361 gcgtgctaac ctcgattggt cattatctct acacgccgcg tgaagatgcg ttgtatatca
    27421 acatctacgc aggaaacagc atggaggtgc cggtagaaaa tggcacgctg cgcctgcggg
    27481 ttagcggaaa ctatccgtgg caggaacagg tgacgattgc ggttgaatca ccccagccgg
    27541 tgcgtcatac gctggcttta cgtctaccgg actggtgcat acagccgcag atcatattga
    27601 atggggaaga ggtcgagcag gatattcgta aagggtattt gcacattacc cgtgaatggc
    27661 aggagggcga cacgctgaat ctgactttgc caatgccggt acgtcgcgtt tacggtaacc
    27721 cgctggtgcg tcacgtcgcc ggaaaagtgg cgattcagcg cggcccgctg gtgtattgtc
    27781 tggaacaggt cgacaacggc gagtcactgc ataatctgtg gctgcccgcc gatgcgccat
    27841 ttacgacatt tgaaggtaat ggattgttcc gccataagat cttaatccag gcaccgggtt
    27901 accggtatga acagagcaat ccagagcagc aaccgctgtg gcattacgac agcgcgccag
    27961 ccaaacgcca gccgcaaatt ctgacgttta tcccgtggtt tagctgggcc aaccggggtg
    28021 aaggcgaaat gcggatctgg gtgaatgagg aaaccagtgc catccgtagg taggataagg
    28081 cgctcgcgcc gcatccaacg catggtgcac attgccggat gcggcgtgaa cgctttatcc
    28141 gacctacaaa agcatgcaaa ttcaatatat tgcatgagct atgtaggcat gataagacgc
    28201 gaaagcgtcg catcaggcaa tgaatacccg atgcgaccag cttcttacat cagaacagcc
    28261 ccaacggttt atccgagtag ctcaccagca ggcacttggt ttgctggtaa tgctcaagca
    28321 tcattttgtg ggtttcacgg ccaatgcctg attgtttgta gccgccaaac gccgcatgtg
    28381 ccgggtaagc gtgataacag ttggtccaca cgcgccctgc ctgaatgccg cgccccatct
    28441 tataggccag attaccgttg cggctccaga cgcccgcgcc cagaccatat tgcgtatcgt
    28501 tcgccagctc cagcgcttct tccatcgttt tgaaggtggt taccgccagc accgggccaa
    28561 aaatctcctc ctggaacacg cgcatattgt tctgaccaaa cagaatcgtc ggttcgaggt
    28621 agtagccgtc tttcagttcg ccttccagca gcttacgtcg cccgccggtg agcacatcag
    28681 cgccctcttt tttaccgata tcaatgtagt tgaggatggt ttccagttgc ccgtaagaaa
    28741 cctgcgcgcc catttgcgtc acgctgtcga gcgggttacc gctgcgaatg ctttcgacac
    28801 ggcggatagc gcgttccata aagcgttcgt agatagactc ctgcactaaa gcacggcttg
    28861 gacaggtgca aacttcgccc tggttaaagg caaacagtgc aaagccttcc agcgctttat
    28921 cgaaaaaggc atcttcttca tccatcacat cagcaaagaa gatatttggc gatttgccgc
    28981 ccagctccag cgtcaccgga ataatgtttt gcgtggcgta ttgcataatt tgttggccca
    29041 cttccgttga gccggtaaac gccactttgg cgatgcgttt cgaggtcgcc agatattcgc
    29101 caatttcccc acctgcgcca ttgaccacgt tcaccacccc tggcggcagt aaatcaccga
    29161 cgatttccat tagcagcagt acagaaagcg gagtaagacg tgcgggtttc agcaccacac
    29221 agttgcccgc cgccagcgcg ggggccattt tccagctcgc catcagcagc gggaagttcc
    29281 acgggataat ctgccccacc acgcctaacg gttcatggaa atgataggcc acggtttcgc
    29341 tatccacttc actgatccca ccttcctgcg cccgaataca cgaggcgaaa tagcgaaaat
    29401 gatcaatcgc cagcggcacg tcggcagcac tggtttcgcg aatgggtttg ccgttatccc
    29461 aggtttctgc cgtcgctaaa agttcaaggt tttgttccat tcgatcggca atcttaaaca
    29521 gaatcgccgc gcgatcctgc accgaggtgt gcgcccattt atctttcact ttatgcgcag
    29581 catccagcgc cagatcgatg tctcgtttgc ccgaagacgc cacttcgcac agtagctgcc
    29641 cggtcaccgg cgtcaggttc tggtaatact cgccatcggc aggcgctacc cattcgccac
    29701 cgataaagtt gtcgtagcgg gcttttaatt tgagggggaa accatactcg ccgggcttaa
    29761 tctgtgctga agggggatta ttggtcatga tcgtctcctt gcggtgtgag gtataacaag
    29821 ggtagacgtg actggcgaaa tcttcgccag tcggtaacag ctttacgacg gctatcacga
    29881 atttacgggc aaaagctaca gcgggtagtg tgcgacgtac actgcttgct ggttattaat
    29941 tcttttctct tgcgcgaatc cttctttaac aattgtccgt aaatcagctc gagccgtatt
    30001 atcagagacg cccaagctcg cgctaatttc agcaactgtg tactctttcc ccggattggc
    30061 gagcatcaca ttcaggagcg ttacctggcg cggattcagg cgtttaagca caccagagct
    30121 aaacagcaca ctatcgagtt ttgcgcttcg ttgtgtaatt tcatcgatat gctgctgcca
    30181 gttttgcaga gcacgtttaa tgacacccgc ctgatattca aggaaataag tcagatccat
    30241 accatctgat tcagtgtact ggtagctggc ggcatatttg accggtgcag catgaagcaa
    30301 acggctgatg gaaatatatt taaagacatc gtagcccgat ttcagcatat accagtaaaa
    30361 cagcgcccga ctggtgcgcc cgttgccatc ccgaaacgga tgttcatggg ccagcataaa
    30421 atgcagaatg caggcacgga ccaacggatg aatataccct tcatggctgt ttaaccactg
    30481 gcaaactttt tccagccgtt ccggtaacaa tgccgcagcg ggcggttgat gcactatatt
    30541 gccatcatag tcggcgatca caacatcatc tgtttcacga aattctcccg gacgatattt
    30601 cgcgtcattg attccaccca taccaatggc atgtaactgg cgaataagcg caggtgtcag
    30661 cggttctgcg agtaagtgcg gaatttccgc catcagccgg gcatttcccg caatcatatg
    30721 ctcgtcttca gtgcgtggcg accgccctgt ttccagcatt tttctcgcca ccagcgttgt
    30781 agtattcgca ccttccagct gggagctggt gatcggctct tccaggcgta actggcttaa
    30841 ctcggctccg gccccgcgta accgttcagt ctgatctttc agcgccagcg cggtagcacg
    30901 tttgtcgaca agctcgcacg cttctgcaat caccggggta atgttgaatc cggcctgttc
    30961 acccgcttca ttgcaataat taattcgttg gatcgccgcg ttgcgcgcca gacgggtaag
    31021 cgtccacgcc acatcgacgt tttctccttt tttgatgcgg tactgcaact catcaaaagg
    31081 cagataacgt cctttttcat cggtaacccg gttaaagcgc aggtgggcca ggagttcctc
    31141 acccgataag tgtgataaag gaataagtcc gggaggtgat ttgatagcca tgtgcttatc
    31201 tcaaaaaagc gcaatattga gatagtgtat agcaggaaag agaaactatc tcaaaaaaag
    31261 caagttttga gatagttgaa aaagcggctg acaactcgcc agccgttgtg ggaatgatga
    31321 ttacatcgct gcgcgataaa tcgccacaat ttcttcgtga gttgcctgga tcgggttagt
    31381 aaagccgcag gcatctttca gggcattagt cgccagaacc gcgaaatctt cttctttcac
    31441 gttcaggtcg cgtaggcctg ccgggatatc cactttcttc gccagttcac ggatggcgtt
    31501 aatgcaggct tcagcacctt ccgcgtcgtt tttacctgtc acgttcacgc ccattgcagc
    31561 ggcacaatca cgcagacgtg cagcggcgac tttgctgttg aatacctgaa catgcggcag
    31621 caaaacggcg ttacatacac cgtgtggcag gttgtagaaa ccgcccagct ggtgcgccat
    31681 cgcatgaaca taacccagag aagcattatt gaacgccata ccggcgagga actgggcata
    31741 agccattgct tcacgcgctt tcgcattact gccatcttca acggctaacg gcaggttttc
    31801 ggcaatcatg gtcacggctt tcagtgcaca agcgtcagtg atcggcgtgg cggcaataga
    31861 aacatacgct tcgatagcgt gcgttaaggc atccataccc gttgcggcgg tcagtgactt
    31921 cggcataccg atcatcagag aggagtcatt gacagaaagc agcggagtga catgtttatc
    31981 cacaatcgcc attttgatgt gacgcgcttc gtcagtgatg atgcaaaaac gggtcatttc
    32041 agaggccgta cccgccgtgg tgttgatggc gatcatcggc agctgcggtt ttgcagagcg
    32101 gtcaacgcct tcataatcgc ggatgtcacc gccgttggct gcaaccagcg caataccttt
    32161 tgcgcagtcg tgtggagaac caccgcctaa ggaaatcacg ctatcgcaat tattttcttt
    32221 aagtaatttc aaacctgcag cgacgttttc cgtggtggga ttaggttggg tgccatcata
    32281 aataacgcta aaaatattgc gttcttccag tgctttttgc acatcacccg ccatacccaa
    32341 tttcgttaac atattgtcgg tgacaattaa ggtacgggta aatccataat ctgccatcat
    32401 attcattgca tcattcaatg aatcagcacc aataacattc acggaaggaa taaaaaaggt
    32461 tgaagctgcc ataacacact cctgaaagtg taaaaaaggg cgggcagctt actgagaatt
    32521 ttcatttgaa aatatgatca atattaccgt ttattaaaat atttttaata aaaagcacgt
    32581 tacattcatc aaataacgtg ccttcttaac attaataaga aattttgtat taattcatat
    32641 ttattatgaa ttaatcattt ccttattttt ccggaaataa taatgcgtcg cgcaataaat
    32701 gatcatttcc acgacgacgc gtaaagccaa tgcggtcaaa atattccaga atctgaattg
    32761 ccagcttgcg gcctacgcct aagcgatcgc ggaaatccgc cgcgcaggtt gaaccacatt
    32821 cctgatcgag atcgcggatc atattggcaa attcgacaat ccgatcgtta cggtaataac
    32881 gatctttgac gatcgcagta attatcccct gttgggccgc ctggcgtagc gtcaggcgca
    32941 ttgcctgctc gtcggttccc gtctcttttg ccaggtcacg cacccaccat ggctcgtcac
    33001 caaacagcgg ctctgctttt tgccagatgg cctgctgctc ttcgctgaag cccgctttat
    33061 gatccggcag atgcagccag ccgtgatggc tgtggatgtc gccgctttcg cgcatctttt
    33121 caatcagcaa cagtaccagc gcttcatctt ccattggcaa cgccatacgt cgcagacgtt
    33181 cgcgcccagg accaggttca tcgcgatgtt gctcatgata agtcgctaat gtgtcgagaa
    33241 ttttccgctg ccagcgggcg gcaactggcg cattcaacaa gctgtaacca gcctgaatat
    33301 agccaggctg ttgcagcagt tcgcgcatcc cttcgccgtt gagctgccgt gcccaggcga
    33361 aatccgcaag gttaaccgcg ccgcgttcca gatgaacaga taacgcatcg gcatcgctct
    33421 gcgcccgtgc aagagacgcc agccattgca gatattccgg cttacgctta ccgcgacgcg
    33481 gcgggttaag catcaccaca cgcgcccccg ccagcgtgtt gcgggccgag atatcgcgca
    33541 gcactatgcg atcgttatcc gccagccaca gcggcgtgtc gaacaccagc tcggcaaggt
    33601 tatcttccag tagcgaaaca cgtcccgtaa cgtggctggc ggcgtggtga atatgcagcg
    33661 gctgccactg ggtcagcggt gtatgggttt gaagctcgac aatcacccgt gtgaacggct
    33721 ccggcggcac atcggcaagc agccagtcgc cacggttaat ctgctctttt tccgcatcac
    33781 ccgcgatgtt aagcgcgata cgctgcccgg catgggcagt ttctgttggc tgattttgcg
    33841 catgcagcgc acgcacgcgc atcggtttat ttacaccagt cagccagagt gaatcgccta
    33901 ctttcacttc cccgcttaac gccgtaccgg tgacgaccag cccggcacct tttacggtaa
    33961 atgcgcggtc gatcgcgagg cggaaactat gttggctggc gtgttcacgt tctggtaact
    34021 gaagcagatg ctcgcgcagg gcatcaattc cccgaccttc ggttgctgcg gtgataaaca
    34081 gttttgcctc agcaaaaccg tattcccgca gcacctcctt tacctggcgt tcaacctcat
    34141 caacacgcgc ttcgtccacg cgatcggctt tggtcagcgc cactgtcagc atcgggttac
    34201 cggtcagctg caaaatcgcc agatgctcac gggtctgtgc catcacaccg tcatcgcacg
    34261 ccaccaccaa cagcgcgtga tcgataccac caacgcccgc cagcatgttg gaaagaaact
    34321 tttcatgacc gggtacgtcg ataaaaccag gcacgcgacc atccggctgc ggccagtagg
    34381 catagccgag atcgatggtc atgccgcgct ttttttcttc cggcagacgg tcggcattta
    34441 cgcccgtaat cgcctgcaac aaggttgttt tgccgtggtc aacgtgtccg gcagtcgtaa
    34501 taatcatttc aacaacatct ccaaaaaccg ttgctcatct tcaaggcagc gtaaatccag
    34561 ccacaatcgt ccgtcataaa tacgaccaat caccggcact ggcaattcac gccagcgggc
    34621 ggctaatgac tcaaggtggc taccgcgtcc atcatggggg gtaaacgtta atgccgcgct
    34681 cggcaggcga tcaaccggca gcgaaccact gccgatctgc gaaagacatg gcataacctg
    34741 taccgcaaac tccgcgccgt aatgtgcggc aaggagagcc tgtaaacgtt gtgcctggat
    34801 ttgaatgacc tctgcgctgc gggtaagcag gcgcagggtc ggtaattttt cactcagagc
    34861 ttcagggtgt aaataaagac gcaacgtggc ttccagcgcc gcgagggtca ttttatccgc
    34921 gcgtaatgca cgcttcagcg ggtggctttg caggcgggcg atcatttctt ttttaccaac
    34981 aataattcct gcctgcggcc cgcctaacag cttgtcgccg gagaagctca ccagactgac
    35041 gcccgccgca atcaactcct gcggcattgg ctctttcggc aaaccgtact ggctaagatc
    35101 gaccagcgag ccactgccta aatcagtcac cactggaaca tccagttctt tgccgagcgc
    35161 caccagttcc gcttcatcta tcgctttggt gaacccctga atgctgtagt tactggtatg
    35221 tactttcatc aacagtgcgg tattttcatt caccgcctga cgataatcat tcgcgtgcgt
    35281 gcggttggtg gtccctactt cgtgtagggt gcatcctgcc tgacgcataa catcgggaat
    35341 acgaaacgcg ccgccaatct ccaccagttc gccgcgagaa accaccacct ctttcccgct
    35401 ggcagtggcc gccaacatca ataacaccgc cgccgcattg ttattaacga tacaggcatc
    35461 ttccgccccc gtaatacggc acagcagctg cgccagcgcc cgatcgcgat gtccacgtcc
    35521 ggcgtcgtcc agatcgtact cgagggtcac tggcgaacgc atagccttcg taacggcttc
    35581 caccgcggct tccgcctgta aagctcgccc aaggttggta tgcagcacgg ttcccgtcag
    35641 gttgatcacc ggacgcagcg cgctttgcgc ctctttcgtc aaccgggcat cgacttcttg
    35701 cgcccagttt tcacaccacg cgggcagcgt ctggctgtca cgaatcactt ctcgcgcttc
    35761 gtcaagcatc tgacgcagca attccaccac gcgggtgtga ccataagtat cacgcaaaga
    35821 aaggaaggag ctatcgcgca ataagcgatc aatagccgga agttgactat agagggaacg
    35881 cgtttcggtt gtcataggaa acctggctga tcaaggccct ctcacacgga gaagggcgtt
    35941 taacataacc acggattgta acgtgagatg ggtcaggagg acatatcgcg catcaagcct
    36001 ttggcggttc ggtgcgagca aaactttcgc ggctaaacag gttttcgacc agtttgacta
    36061 agtgtgggcg gtcgacacac cagcctggcg caacgcggcg gaaattgaga tatccgaccg
    36121 cacaggcaat ggcgatagtc gccagattga ccgtatcggt tttgagcgtg ccatcgacca
    36181 gatatccttc cagcacatcc agactgcggt tgattttctc acgctgacgt aacaattcat
    36241 cttcagactg ctgcgccgcc ggacgcgcct gttcacgcac cgataccagc ccggcatcca
    36301 taatgccatc cgccagcgcc tcaattttgc gcacccgcaa cgactccagc ggatcacgcg
    36361 gcaacatcgc cggagcaaca ttcattaatt caatatattc agcgatgatc ggcgaatcaa
    36421 accagcattc gccctcttcg gtcaccagca ccggcacttt tcctaacggg ttaaattgcg
    36481 ccacgccgtt gtccgcgtta tagggcagtt cattaataaa ttcgaacgtt atgccctttt
    36541 ctaacaacag aatagaaagt ttgcgtacaa acgggctggt gtagctaccg acgagtttca
    36601 tgccgagtcc tttgtgcgag gaaaaatatc agtatggctc aggctcgcgc aaaacacagg
    36661 tgatacaagt ctcaatgatc caaataaaga taatgcatcc aactggtcat tcttagcagc
    36721 actttccgca tcaccgaaac atggctgaaa tggtcggagt aaactgccac ctgggcgtag
    36781 atgccgtcgg gtaaggcatc gatatcagcg ttagggtcca gctcaatggt tcccagcaca
    36841 ccgtccgtgc cgggcacgac cgttaatgat tgcaataccc cctgcgcctg ataagaaccg
    36901 cctggcacga caggtaaaat actggtcagt ttgccgtgaa acacctgccc aggtagcgcg
    36961 ttaaacacca cttccgcatc atcgccgggt ttcagacgta acagcgagtt ttgccgaaat
    37021 tgggcgacaa tttgccgttt ttgctcgggg atgaagacca tcaccggacg cagcggcaag
    37081 gcagcggcgt atgtacctgg gcggatcagt acctgagtga cgtagccatt gctcggtgcg
    37141 cgaatgacgg tctgctcaag gttatatttt gcttcagtaa gttgcgctct taagctcaca
    37201 atctgcgatt gctcgccgtt aaccatactg tcgagctggc tctggatctg cgcctgctcc
    37261 gccaccgagc ctttcaccag cgcatcctgc gcgaggaaat tttgccgcgc atcgtcgatg
    37321 tcacgttccg agaacggatt caccgccgcc tggctgcctt tcagataacg ttgataattt
    37381 ttaaacagac ggtcgcgctc cgctgaaacc tgggtggtgt tggcctgcgc ttcagtgagt
    37441 tgcgcgcgca gcgtctttat attatgcgtc gccgtcatca ggtctgcctg aagtctgtca
    37501 actcgcgcct ggtaacgaac cggctcgagc ttaaaaagca cctcgccctt ctgaataagc
    37561 tgattatttt tgtcggtgac ttcagtaaca attcccgtca cctgtggcgt gatggggatc
    37621 gctatcactg ccttttgcgc ggtaaaagtg taagggtggt tgtagttcat caacaagatc
    37681 aaaccactca ccagaaacac gcctcccagc gccgccgtcg ccagcgtcca ctgatttacc
    37741 ggaatgcgga agattttaaa gaccgcccac gccagcgcca cgtaagttaa aacaatcaat
    37801 agatccatat ttagatctcc ggaaacgtgg aatagtcagt ctttttctcg gcggcgagtt
    37861 gatgctccag ccgggaaatt cggtcagaaa gtgcggcgat ttccgggtca gtcgctttct
    37921 cttgcgacgc aacatgtgac tgcatgcccc agccgcgctc cggttgatag agcgtcgccc
    37981 agatccacag gaacggccag ataacatgta gagtaaacag gctcacccag cccgccgtat
    38041 gaatagcgtc ggcatgggga tggttgcgct ttttggcaat cagataaggg atgtcatgta
    38101 tcgcgatgat tccataaaaa atcaccagaa agacgaagat cagcactccc aacgcgaaat
    38161 agtttagaaa catatctgcc tcggattcac gtttatcagt gttgtttttt ggctggcagc
    38221 cagaagggag tcaggctgat attttgacaa taatccgggt tcgcgattct cgccataaca
    38281 ccaaagaata attttaagag gtgatgagtt gcttagttac ataacgattt catgacgaag
    38341 gcataacatg ctgtagatca catcaggtga acgccgtaag aaaatatctt gtgattcaga
    38401 tcacaaagat tcaacaaacc atcaaaacaa aaatgtgaca ttactcacat ttaaatgcca
    38461 tttttagcga aaatcgccgc cttgttgctt ttttacacaa gcattttgtg atgagcatca
    38521 cgtcaattac ctctctaccc cctacattta tgtgactgat atcacacaaa aggccgccga
    38581 ctggacagtt aaccgattca gtgccagatt tcgcagtatc tacaaggtcc ggctacctct
    38641 gccgccacat taacaaaaaa cctcgggctt ccagcctgcg cgacagcaaa cataagaagg
    38701 ggtgttttta tgtcatccga tattaagatc aaagtgcaaa gctttggtcg tttcctcagc
    38761 aacatggtga tgccaaatat cggcgcgttt atcgcgtggg gtatcatcac cgcgttattt
    38821 attccaacag ggtggttacc gaacgaaacg ctggcgaagc tggtcgggcc gatgatcact
    38881 tatctcctgc cgctgctgat cggttatacc ggtggtaagc tggttggcgg cgaacgtggc
    38941 ggcgtagtcg gtgccattac caccatgggc gttatcgtcg gcgcagacat gccgatgttc
    39001 ctcggctcta tgattgcagg tccgctgggc ggctggtgca ttaagcactt cgaccgctgg
    39061 gtagacggta agatcaaatc cggttttgag atgctggtga ataacttctc cgcaggcatc
    39121 atcgggatga tcctcgctat tctggcattc ctcggcattg gcccgattgt tgaagccctg
    39181 tccaaaatgc tggcggcggg cgttaacttc atggttgtcc atgacatgct gccgctggcg
    39241 tctatctttg ttgaaccggc gaaaatcctg ttcctcaaca acgccattaa ccacggtatc
    39301 ttctcgccgc tgggtattca gcagtcccat gaactgggta aatccatctt cttcctgatt
    39361 gaagctaacc caggtccagg tatgggcgtg ctgctggcgt acatgttctt tggtcgtggt
    39421 agcgctaaac agtctgcggg cggtgcggca atcatccact tcctgggggg tatccacgaa
    39481 atctacttcc cgtatgtgct gatgaatccg cgtctgattc tggccgttat cctcggcggt
    39541 atgactggcg tattcacgct gactatcctg ggcggtgggc tggtttctcc ggcatctccg
    39601 ggttctatcc ttgctgtact ggcgatgacg ccaaaaggtg cttacttcgc taacatcgcg
    39661 ggtgtgtgtg cggcgatggc agtttccttc gttgtctctg ccattctgct gaaaaccagc
    39721 aaagtgaaag aagaagatga tattgaagct gctgcacgtc gcgttcagga aatgaaagct
    39781 gagtctaaag gtgcgtctcc gctgtctgca ggcgatgtga ctaacgacct gagccacgtc
    39841 cgtaaaatca tcgttgcctg tgatgccggt atgggttcca gtgcgatggg tgcaggcgtg
    39901 ctgcgtaaga aaattcagga tgcaggtctg tcgcagattt cggtcactaa cagcgcgatc
    39961 aacaacctgc cgccagatgt ggacctggtc atcactcacc gtgacctgac cgaacgcgct
    40021 atgcgccagg ttccgcaggc acagcatatt tcgctgacca acttcctcga cagcggcctg
    40081 tacaccagcc tgaccgaacg tctggttgct gcccagcgcc atactgaaaa cgaagtgaaa
    40141 gtgaaagaca gtctgaaaga cagctttgac gattccagtg ctaacctgtt caaactgggc
    40201 gcggagaaca tcttcctcgg tcgcaaagcg gccaccaaag aagaagcgat tcgttttgct
    40261 ggcgagcaac tggtgaaagg cggttacgtt gagccggaat acgttcaggc gatgctggat
    40321 cgtgaaaaac tgaccccgac ttatctgggt gagtctatcg cggtgccaca cggtacggtt
    40381 gaagcgaaag atcgcgtact caaaacgggc gtcgtgttct gccagtaccc ggaaggcgtg
    40441 cgcttcggtg aagaagaaga tgacattgcc cgtctggtga ttgggattgc tgcccgtaac
    40501 aacgagcaca ttcaggtgat caccagcctg accaatgcac tggatgatga gtccgtcatc
    40561 gagcgtctgg cacacaccac cagcgtggat gaagtgctgg aattgctggc aggtcgtaag
    40621 taatccattc ccaccctctc cgcatgaaga aggtggggct aattgcttga tgcgcttcgc
    40681 ttatcaggcc tacaacataa agcacaattt gttttgtcgg tcggataagg tgtttacgcc
    40741 gcatccggca gtcggtgcac aatgcctgat gcgacgctga cgcgtcttat cagacctaca
    40801 ggtcagtgcc aaacacgtag gccggataag gcggtttacg ccgcatccgg caaaaagccc
    40861 ctctcctcac ggagagggtt tgggtgaggg aaaagcctca ccccagccct ctcgggtaaa
    40921 aacattgatg aaggttaata ctatgaaagc attacatttt ggcgcaggta atatcggtcg
    40981 tggctttatc ggtaaactgc tggcagacgc aggtatccaa ctgacgtttg ccgatgtaaa
    41041 tcaggtggtg cttgatgccc tgaatgcccg tcatagctat caggttcatg tggttggtga
    41101 aaccgagcag gtagataccg tttctggcgt cgatgccgtc agcagcattg gtgatgatgt
    41161 cgttgatctg attgctcagg ttgatttagt cactaccgcc gttggcccgg tcgtgctgga
    41221 acgtattgct ccggccatcg ccaaagggct ggtgaaacgt aaagaacaag gtaatgaatc
    41281 tccgctgaac atcatcgcct gtgaaaacat ggtccgcggc accacgcagc tgaaaggcca
    41341 tgtgatgaac gccctgcccg aagacgccaa agcgtgggta gaagaacacg ttggctttgt
    41401 tgattccgcc gttgaccgca tcgtaccgcc ttcggcttcg gcaactaacg atccgctgga
    41461 agtgacggta gaaaccttca gcgaatggat tgtcgataaa acccagttca aaggcacgct
    41521 gccaaacatc cctggcatgg aattaaccga caatctgatg gcatttgtcg aacgtaaact
    41581 cttcaccctg aatacaggtc atgctataac cgcgtacctc ggaaaactgg cgggtcatca
    41641 gaccattcgt gacgcaattc tcgacgagaa aatccgcgcg gtggtaaaag gggcaatgga
    41701 agaaagtggt gcagtattga tcaagcgcta cggctttgac gctgacaagc atgcggcata
    41761 catccagaaa atccttggtc gtttcgagaa cccgtacctg aaagatgatg tagaacgcgt
    41821 aggccgtcag ccgctgcgta aactgagtgc tggcgaccgt ctgatcaagc cactgctcgg
    41881 aaccctggaa tatggtctgc cacataaaaa cctgattgaa ggtattgccg ctgcaatgca
    41941 cttccgcagt gaagatgatc cgcaggctca ggaactggca gcgctgattg ccgacaaagg
    42001 cccacaagcc gcgctggcac agatttccgg tcttgatgcc aacagcgagg ttgtatccga
    42061 ggcggtaacc gcttataaag caatgcaata atggtggacc aggcgcagga taccctgcgc
    42121 ccgaataaca gattgtcaga tatgcaggca acaatggaac aaacccaggc ctttgaaaac
    42181 cgtgtgcttg agcgtctgaa tgctggcaaa accgtgcgaa gctttctgat caccgccgtc
    42241 gagcttttga ccgaggcggt aaatcttctg gtgcttcagg tattccgcaa agacgattac
    42301 gcggtgaagt atgctgtaga accgttactc gacggcgatg gtccgctggg cgatctttct
    42361 gtgcgtttaa aactcattta cgggttgggc gtcattaacc gccaggaata cgaagatgcg
    42421 gaactgctga tggcattgcg tgaagagcta aatcacgacg gcaacgagta cgcttttacc
    42481 gacgacgaaa tccttggacc ctttggtgaa ctgcattgcg tggcggcgtt accaccgccg
    42541 ccacagtttg aacctgcaga ctccagtttg tatgcaatgc aaattcagcg ttaccaacag
    42601 gctgtacgat caacaatggt cctttcactg acagagctga tttccaaaat cagcttaaaa
    42661 aaagcctttc aaaagtaagt actttcgctt acttctcctc tacctgtttc ggacgataaa
    42721 gctgacgata atactccaga cgttgtagat ataacggcac gctttcatca ggtattccgg
    42781 acggaatcgc gttacgggga ggtagttttt tcagatactc ccggaacgcc tggctcgatg
    42841 ccatgaaatc tacggcttta tcgataagaa gcggaacgtt ttcacctaat ttgcccatga
    42901 tgatatctcc gtattacccc gcgccgggaa tgcgcggccg ccaattttag tttagatccc
    42961 ggtataaatg acattaagga aaacgtgctc aatcctcaat aatcacctgc ttctgttgac
    43021 tatctttttt ctttaaattt cttaactaat caatgtattg ggtgattttt taacgcatta
    43081 atggttacaa tctggaacta ttacaatgcc atcagttgtg aacaaagcac ctggtcgcgc
    43141 atactagagg ctataaattt atctctatca gaagtcatca catgaaagaa gtcgaaaaaa
    43201 acgaaatcaa acgtctcagc gatcgtctgg acgccatccg tcaccagcag gccgatctat
    43261 cgctggttga agccgcagac aaatatgccg aactggaaaa agagaaagcc acgctggaag
    43321 cagaaattgc tcgcctgcgc gaagttcaca gccagaaact cagcaaagaa gcgcagaaac
    43381 tgatgaagat gccgttccag cgtgcaatca ccaaaaaaga gcaggctgat atgggcaaac
    43441 tgaaaaaaag tgttcgcgga ctggtggttg tgcacccaat gaccgcgctg ggccgtgaaa
    43501 tgggcctgca agagatgaca gggttctcaa agactgcgtt ttaagttcct ttctcgtcgc
    43561 tgtaactact gccactcacg atttactcgc tcctgctggc acatgcagga gcctgtgcca
    43621 ctcattaaat acgatgtctt tcttaccgta aactgtttca gtttcccctc gagtttgagg
    43681 tatttttgca ggctaaaatc tgaaaatttg tt
//
LOCUS       DAFGPF010000030        43052 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFGPF010000030 DAFGPF010000000
VERSION     DAFGPF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43052
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.030"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            116..391
                     /locus_tag="LSX49_001851"
     CDS             116..391
                     /locus_tag="LSX49_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168273.1"
                     /translation="MPTVLSRIAMQLKKIAWIIPVFMVSGCSLSPAIPVIGAYYPGWF
                     FCAIASLILTLITRRIIQRTNINLAFVGIIYTALFALYAMLFWLAFF"
     gene            410..1441
                     /gene="mdtN"
                     /locus_tag="LSX49_001852"
     CDS             410..1441
                     /gene="mdtN"
                     /locus_tag="LSX49_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HBL7168274.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVSDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSVNATVEKARAAAKQASDTLRRTEPLLREGFVSAEEVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGA
                     SAVANLEPQ"
     gene            1441..3492
                     /gene="mdtO"
                     /locus_tag="LSX49_001853"
     CDS             1441..3492
                     /gene="mdtO"
                     /locus_tag="LSX49_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313090.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HBL7168275.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAITQMHQALNDRLDDAISHLTDSLAPLPETRIEREAL
                     ALQKLNVFCLADDANWRTQSAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAIAEGQCWQSDWRITESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     TKPPSIVADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGALGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVVLERQLD
                     SEERALLIERSQTVIRQGRDILHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPAKEQAQGAT
                     Q"
     gene            3489..4955
                     /gene="mdtP"
                     /locus_tag="LSX49_001854"
     CDS             3489..4955
                     /gene="mdtP"
                     /locus_tag="LSX49_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HBL7168276.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLNGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYAMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAISAHNAALAETAAVELSLTTGVAQLYYSMQASYQMLDLLEQTRDVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIAAVKGQITETRESLRALIGAGASDMPE
                     IKPVALPQVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDSIHLDTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAAPVVEKK"
     gene            5153..7300
                     /locus_tag="LSX49_001855"
     CDS             5153..7300
                     /locus_tag="LSX49_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5570..5572,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HBL7168277.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAESAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRVAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            7675..9243
                     /locus_tag="LSX49_001856"
     CDS             7675..9243
                     /locus_tag="LSX49_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL7168278.1"
                     /translation="MIKKLLPLLVLSTISATTVAATPPNTLVVAQGLDDIVSLDPAEA
                     NELSSIQTVPSLYQRVVQPDRNDPTKITPILAESWQADPAAKTLTIKLKSDAKFASGN
                     PVRPEDVIYSYVRAVTLNKSGAFILNVLGWQPENIASQLKKIDDHTVQVQWSADVSPA
                     LALNILSTPIASIVDEKLVAPNAKNNDFGNEWLKMHSAGSGAFKMRTYQPHQAIVMEA
                     NASSPTGAPKLKSVIIKNVPDPATRRLLIQQGDADMARDLGADQIDALQGKPGVKVMS
                     IASAEQNYLAFNTGNKDNPLMSNPAFWEAARWLVDYDGITKNLLKGQYFTHQSFLPVG
                     FPGALEETPFTFNPAKAKEILAKAGIKDPHFTLDVENKPPFITIAQSIQASFAQGGVK
                     VDLLPAAGSQVYSRVRAHQHQGAIRMWLPDYFDAHSNASSFAYNDGKSSTVAGLNGWK
                     IPELNKETLAAIAEPDSTKRLDLYKKMQQELQRSSPYVFIDQGKTQIVMRDNVQGYQQ
                     GLNADMVWFDQVTK"
     gene            9343..10392
                     /locus_tag="LSX49_001857"
     CDS             9343..10392
                     /locus_tag="LSX49_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7168279.1"
                     /translation="MSVVFSTRARWRGKRPLLALLQGLFTVALTLLGLLLITFALSAL
                     SPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLAVQFWHYLMNLAHGDLGIASSTGQPV
                     LQDLLSAFPATIELATLALIVGAVVGVIAGVLCARYVGSPLDFTVRTLTLLGNSVPVF
                     WLGLLMLALFYARLQWSAGPGRLDDIYQFTIEPRSGFALIDTWLSGDREAFTNAINHL
                     ILPVLLLAYFSLASITRLTRSACLGEMNKEYILLARAKGASEMTILLRHVLPNIRGTL
                     LTVIALAYTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVCFVLIN
                     NLTDLLVRLTDPRLR"
     gene            10392..11225
                     /locus_tag="LSX49_001858"
     CDS             10392..11225
                     /locus_tag="LSX49_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7168280.1"
                     /translation="MPMFLFLRRLRHSPAAFCGLIIILLLMLIALFAPWLAPHDPNWQ
                     DAAARLQAPSRQHWLGTDSYGRDLLSRLIYGSRPALGLVALVTIITLPVGLLIGILAG
                     YYGGWLERVLMRFTDIVMSMPRLILAFAFVAMLGPGLVNGALALALTTWPAYARQARS
                     EIQRLRHSDYLAAAEMMGIRGRRLLAGHILPLCLPSAIVRLALDLAGIILAAAGLGFL
                     GLGARPPMAEWGAMIADGMQVIFDQWWIAAAPGAIILIASLAFNLLGDGLRDVLEPQH
                     D"
     gene            11218..12054
                     /locus_tag="LSX49_001859"
     CDS             11218..12054
                     /locus_tag="LSX49_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7168281.1"
                     /translation="MTDSRLSINNLCVDYPESRVVNNVSFTLGNERLALVGESGSGKS
                     MTARALMGLVRKPGVVTADTLNILGRDALTLNARGWQQLRGNDIAMVLQDPRYALNPV
                     KTVKAQLEEALTLHQRLNRREKEEKINTAIQAVGLNTRVLQSYPRELSGGMGQRVMIA
                     IALINDPRVLIADEPTSALDVRLRNQILELLVTQCEQRQMAMLLISHDLPLVAQFCHR
                     VLVMYQGNKVDEMHAAALPTATHPYTRTLWTCRPNAQTYGQMLPTLDRTAMTPEKYHD
                     DC"
     gene            12041..12745
                     /locus_tag="LSX49_001860"
     CDS             12041..12745
                     /locus_tag="LSX49_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7168282.1"
                     /translation="MTIVEINHLQVTFAEKTAVSAASFSVNAGETFSLIGESGCGKST
                     ILRVIAGLQRDWHGQVSLFGHTIKPGMRFQGDLRRNVQMVFQDPYASLHPNHTLWRTL
                     AEPLKIRGEREIEKRVQTALEQVGLPFDAARRYPHQLSGGQRQRVVIARALLLRPQLL
                     LLDEPTSALDMSVQAEILNLLNQLKLEHQMTYLLVSHDADVIAHMSDRAALMSEGKIQ
                     RFFDRDAMEKGEHRMD"
     gene            12856..13545
                     /locus_tag="LSX49_001861"
     CDS             12856..13545
                     /locus_tag="LSX49_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBL7168283.1"
                     /translation="MKKIITLMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(14034..15347)
                     /gene="gltP"
                     /locus_tag="LSX49_001862"
     CDS             complement(14034..15347)
                     /gene="gltP"
                     /locus_tag="LSX49_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HBL7168284.1"
                     /translation="MKNIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREMLGKFDKTADQ"
     gene            complement(15690..16286)
                     /gene="nrfG"
                     /locus_tag="LSX49_001863"
     CDS             complement(15690..16286)
                     /gene="nrfG"
                     /locus_tag="LSX49_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HBL7168285.1"
                     /translation="MKQPQIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRD
                     PLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     RGENAELYAALATVLYYQASQHMTVQARAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD"
     gene            complement(16283..16666)
                     /gene="nrfF"
                     /locus_tag="LSX49_001864"
     CDS             complement(16283..16666)
                     /gene="nrfF"
                     /locus_tag="LSX49_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HBL7168286.1"
                     /translation="MNKGLLTLLLLFTCFARAQVVDTWQFANPQQQEQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYTMVEEGKSEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMALILWRVRAKR"
     gene            complement(16659..18377)
                     /locus_tag="LSX49_001865"
     CDS             complement(16659..18377)
                     /locus_tag="LSX49_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HBL7168287.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLIPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGTCARICWRWALPGW
                     SALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQRGIFRH
                     WSLLLTIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFGLFVLISLASLALYGW
                     RARDGGPAVRFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFALLMLVVIVLATFVSGKRARLPTLLAHAGVLLFAAGIVVSSVSRQEISLN
                     LQPGQQVTLAGYTFRFERLDLQAKGNYTSEKAIVALFDHQQRIGELTPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGADRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GRKRDE"
     gene            complement(18397..19353)
                     /gene="nrfD"
                     /locus_tag="LSX49_001866"
     CDS             complement(18397..19353)
                     /gene="nrfD"
                     /locus_tag="LSX49_001866"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HBL7168288.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAIRQRSNPHSTEAHFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            complement(19350..20021)
                     /gene="nrfC"
                     /locus_tag="LSX49_001867"
     CDS             complement(19350..20021)
                     /gene="nrfC"
                     /locus_tag="LSX49_001867"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HBL7168289.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACRKVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTHL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            complement(20018..20584)
                     /gene="nrfB"
                     /locus_tag="LSX49_001868"
     CDS             complement(20018..20584)
                     /gene="nrfB"
                     /locus_tag="LSX49_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HBL7168290.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASGDRYEVTQQRN
                     PDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            complement(20629..22065)
                     /gene="nrfA"
                     /locus_tag="LSX49_001869"
     CDS             complement(20629..22065)
                     /gene="nrfA"
                     /locus_tag="LSX49_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HBL7168291.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPATPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            22457..24415
                     /gene="acs"
                     /locus_tag="LSX49_001870"
     CDS             22457..24415
                     /gene="acs"
                     /locus_tag="LSX49_001870"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HBL7168292.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSIDAPDTFWGEQGK
                     ILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSSSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGNPLKGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            24625..24939
                     /locus_tag="LSX49_001871"
     CDS             24625..24939
                     /locus_tag="LSX49_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HBL7168293.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPVGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            24936..26585
                     /gene="actP"
                     /locus_tag="LSX49_001872"
     CDS             24936..26585
                     /gene="actP"
                     /locus_tag="LSX49_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HBL7168294.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMLGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(26624..27313)
                     /locus_tag="LSX49_001873"
     CDS             complement(26624..27313)
                     /locus_tag="LSX49_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL7168295.1"
                     /translation="MANFQLSMLCLAITLVIYFLNKRLYRRFRKLPLMPLVLTPTLLV
                     MLLVFGNISWQNYIGEAHWLLWLLGPATIAFAVPVYDNRAIIKRHWMSLTAGVLTATV
                     VAVTSSVWLARLFTLPDEIQRSLAVRSVTTPFALAASQSLGGQPDLVALFVVVTGVFG
                     MAIGDVLFLRLSIREGMAKGAGFGAASHGAGTARSYELGQQEGVVASLVMMLSGVLMV
                     LVSPLVARMMF"
     gene            complement(27306..27716)
                     /locus_tag="LSX49_001874"
     CDS             complement(27306..27716)
                     /locus_tag="LSX49_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL7168296.1"
                     /translation="MPVALRRITPAVVQSIQVFFQVVLYAGLFIFAQYLVSWLHLPLP
                     ANLVGMILMLALIVCRILPLQWVRAGARWLLAEMLLFFVPAVVAVVNYAQLLLVDGWR
                     IFAVIALSTVMVLGTTAWVVEKVYRYEMRRLNRG"
     gene            27820..28704
                     /locus_tag="LSX49_001875"
     CDS             27820..28704
                     /locus_tag="LSX49_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7168297.1"
                     /translation="MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELN
                     CILLIRDGRRLLLTDTGRVVFERGLALLAEFRQLEAELSDINQLKTGVLRLGIPPMVG
                     MLMAGPIGLFRQRYPGVELKISEFGGLTVQQAVMNGELDMALTALPVEESGLTTLSLF
                     SHPLCVLTPHSGKWLECDAVSPETLAEHPLLIYNEDFALSKQLMKLFDEHGVKPRIAV
                     RSGQWDFLAAMVQAGVGIAILPEPICQRLDKNTLKWLPLESELSWKLGMIWREGVYLS
                     HSAHAWLSCCEGYWLTPE"
     gene            complement(28740..30389)
                     /locus_tag="LSX49_001876"
     CDS             complement(28740..30389)
                     /locus_tag="LSX49_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HBL7168298.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSILEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(30540..31889)
                     /gene="ghxP"
                     /locus_tag="LSX49_001877"
                     /gene_synonym="yjcD"
     CDS             complement(30540..31889)
                     /gene="ghxP"
                     /locus_tag="LSX49_001877"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HBL7168299.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFTTFPVMMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(32436..32900)
                     /gene="soxR"
                     /locus_tag="LSX49_001878"
     CDS             complement(32436..32900)
                     /gene="soxR"
                     /locus_tag="LSX49_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HBL7168300.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIREAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            32986..33309
                     /gene="soxS"
                     /locus_tag="LSX49_001879"
     CDS             32986..33309
                     /gene="soxS"
                     /locus_tag="LSX49_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HBL7168301.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(33312..34898)
                     /gene="pdeC"
                     /locus_tag="LSX49_001880"
     CDS             complement(33312..34898)
                     /gene="pdeC"
                     /locus_tag="LSX49_001880"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HBL7168302.1"
                     /translation="MSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIRLNDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLFLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAEFIPLAEKEGMIEQV
                     TDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKF
                     EVTEHAFLDVDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEAQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            35327..35608
                     /locus_tag="LSX49_001881"
     CDS             35327..35608
                     /locus_tag="LSX49_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HBL7168303.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRADYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(35707..36243)
                     /gene="ssb1"
                     /locus_tag="LSX49_001882"
     CDS             complement(35707..36243)
                     /gene="ssb1"
                     /locus_tag="LSX49_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HBL7168304.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            36498..39320
                     /gene="uvrA"
                     /locus_tag="LSX49_001883"
     CDS             36498..39320
                     /gene="uvrA"
                     /locus_tag="LSX49_001883"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBL7168305.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPDGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(39355..39711)
                     /locus_tag="LSX49_001884"
     CDS             complement(39355..39711)
                     /locus_tag="LSX49_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBL7168306.1"
                     /translation="MTILELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(39715..40131)
                     /locus_tag="LSX49_001885"
     CDS             complement(39715..40131)
                     /locus_tag="LSX49_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBL7168307.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRAVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(40242..40955)
                     /gene="aphA"
                     /locus_tag="LSX49_001886"
     CDS             complement(40242..40955)
                     /gene="aphA"
                     /locus_tag="LSX49_001886"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HBL7168308.1"
                     /translation="MRKITQALSAVCLLFALNSSAVALASSPSPLNPGTNVAKLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
     gene            41232..43052
                     /locus_tag="LSX49_001887"
     CDS             41232..43052
                     /locus_tag="LSX49_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL7168309.1"
                     /translation="MKISWNYIFKNKWRFHITSISLFLIMLAVSIAFLHLRFNTLSGT
                     DKMRLEMYKSTLYSTIEQFYVLPYMLSTDHIIRQAVITPDDMTSSELNQRIAHFNTQL
                     KTAAIFILDTQGKAIASSNWQDPGSYVGQNYSYRPYYKHAMSGLNGRFYGIGSTTNTP
                     GFFLSTSIKDKGKIVGVVVVKISLNEIEKAWAEGPENIIVNDEHGIIFLSSKSPWRMR
                     TLQPLPVQAKQKLQSTRQYSLDNLLPADYYPCYTVSNFTFLKDKKEQLCLFPQYYTQQ
                     IAIPEFNWKMTIMVPLDNLYWSWAISLVITLIIYLLFLLFIKYWRMRSHAQQLLTLAN
                     ETLEKQVKERTSALELINQKLIQEIKERSQAEQVLQITRSELAESSKLAALGQMATEI
                     AHEQNQPLAAIHALTDNARTMLKKEMYPQVEQNLKHIISVIERMTQLISELKAFASRH
                     RVPKGSADVIKVMYSAVALLNHSMEKNNIERRIKAPSMPLFVNCDELGLEQIFSNLIS
                     NALDSMEGSSYKRLDIAIRQANNKVIITIKDSGGGFAPEVVDRIFEPFFTTKRRGMGL
                     GLAIVSEIVRNSNGALHASNHPEGGAVMTLTWPEWGEKHE"
BASE COUNT        10687 a        11475 c        10961 g         9929 t
ORIGIN      
        1 tgcggtggct gaataaagct atttttattc atcgagaaaa tagccatact gacgccttca
       61 atggatattg atattcacta cagatattgt tcgcagcaga caggatgtat ttaatatgcc
      121 aacagttctc tctcgcatag cgatgcaact caaaaaaata gcctggataa ttcccgtctt
      181 catggtttcg ggatgctcat tatctccggc aatcccggtg atcggcgctt attatcccgg
      241 ctggtttttc tgcgccattg ccagccttat tttgacgctc atcacgaggc gaattattca
      301 gcggacaaat atcaatctgg catttgtcgg aattatttat accgcccttt ttgctctcta
      361 cgccatgctg ttctggctgg catttttcta atcaatttga gacgcgctca tggaaagtac
      421 gccgaaaaaa gctcctcgca gtaaattccc tgctctgtta gtggttgcgt tggcgctggt
      481 tgcccttgtt ttcgttatct ggcgcgtaga cagtgcgcca tcaactaatg acgcttacgc
      541 gtcagcagat accattgatg tggtgccgga agtcagcggt cgcattgtag aactggcggt
      601 cagcgacaac caggcggtga aacagggcga tttgctgttc cgcattgacc cgcgcccgta
      661 cgaagccaat ctggcgaaag ctgaagcctc cctcgcggcg ctggataagc aaattatgct
      721 cacccagcgt agcgttgacg cgcaacagtt tggtgccgac tcggttaatg ccacggtaga
      781 aaaagcccgt gccgccgcga aacaagccag cgatacgtta cgccgtaccg aaccgctact
      841 gcgagaaggt tttgtttctg cggaagaggt tgaccgtgca agaaccgccc agcgtgcggc
      901 agaagcggac cttaatgccg tattgttgca ggcgcagtca gccgccagtg ccgtcagcgg
      961 cgtcgatgcg ctggtcgccc aacgtgcggc ggtcgaagcg gatattgccc tgaccaaact
     1021 gcatctggaa atggcgaccg ttcgcgcgcc gtttgatggc cgggtcattt ccctcaaaac
     1081 ctccgtcggg caatttgctt ctgccatgcg ccctattttc accctaatcg acactcgtca
     1141 ctggtacgtg atcgccaatt tccgcgaaac tgatctgaaa aatattcgct caggtacacc
     1201 cgcaacgatt cgcctgatga gcgacagcgg caaaaccttc gagggtaaag tggattcgat
     1261 tggctacggc gtgctaccgg atgacggcgg cctggtgctg ggcggcctgc cgaaagtgtc
     1321 gcgttctatt aactgggtcc gcgttgccca gcgttttccg gtcaaaatca tggttgataa
     1381 acctgacccg gaaatgttcc gcatcggcgc ttcggcagtc gctaatcttg agccgcaata
     1441 atgagcgcgc tcaactccct gccattaccg gtggtcaggc tgctggcgtt ctttcatgaa
     1501 gagttaagcg agcggcggcc aggtcgtgtg ccgcagaccg tgcaactctg ggtaggctgc
     1561 ctactggtga ttctgatctc gatgactttt gagatccctt ttgtggcgtt atcgctggca
     1621 gtgctgtttt acggtattca gtcgaacgcg ttttacacca aatttgtggc gatcttgttt
     1681 gtggttgcca cggtgctgga gatcggcagc ctgtttttga tctacaaatg gtcatacggc
     1741 gaaccgttga tccgattgat catcgccggg ccgatcctga tgggctgcat gtttttgatg
     1801 cgcacccatc ggctggggct ggtctttttc gccgtcgcca ttgtcgctat ttacgggcaa
     1861 accttccccg ccatgctcga ctatccggaa gtggtcgtgc gcttaaccct gtggtgtatc
     1921 gttgtcggcc tctacccgac gttattgatg acgttaatcg gcgtgctgtg gtttcccagc
     1981 cgcgctatca cgcagatgca tcaggcgctt aatgatcggc ttgatgatgc cattagccac
     2041 ctgacggaca gcctcgcacc gctacccgaa acgcggattg aaagagaggc gctggcgctg
     2101 caaaaactca atgtcttttg cctcgcggac gatgccaact ggcgaactca gagcgcatgg
     2161 tggcaaagct gcgtggcaac ggtaacctac atttactcga cgctgaatcg ctacgatccc
     2221 acctcttttg ctgattctca ggcaattatt gaattccgac aaaaattagc ctcagaaatc
     2281 aacaaactgc agcatgccat tgccgaaggt cagtgctggc aaagcgactg gcggatcact
     2341 gaaagtgaag cgatggcggc acgggaatgt aacctggaga atatctgcca gacattgttg
     2401 caactgggtc agatggaccc gaatacgccg ccaacgcccg ccaccaaacc gccatcaata
     2461 gtcgccgacg cttttaccaa tccagactat atgcgctacg cggtaaaaac gctgctcgcc
     2521 tgtttgatct gttacacctt ctacagcggc gtggactggg aaggcattca cacctgtatg
     2581 ctgacctgcg tgatcgtcgc taatccaaat gtcggttcgt cgtaccagaa gatggtgctg
     2641 cgttttggcg gggccttttg cggcgcgatt ctggcgctgt tattcacgct actggtcatg
     2701 ccctggctgg acaatattgt cgaattgctg tttgtgctgg caccgatttt cctgttgggc
     2761 gcatggattg ccaccagctc tgaacgctct tcttatatcg gcacacagat ggtggtcacc
     2821 ttcgcgctcg ccacgctcga aaacgttttt ggcccggtgt acgacctggt ggaaattcgc
     2881 gatcgcgctc tgggtatcat cattggtacc gtggtgtcgg cggtgattta cacctttgtc
     2941 tggcctgaaa gcgaagcgcg cacgctgccg caaaaactgg ctggcgcgct gggtatgttg
     3001 agtaaagtaa tgcggatccc acgccagcag gaagtcacgg ctctgcgcac ttatctgcaa
     3061 attcgcatag gtctgcatgc ggcgtttaat gcctgtgaag agatgtgcca acgcgtggtg
     3121 ctggagcgtc aactggacag cgaagaacgc gccttactga ttgaacgttc gcaaacggtt
     3181 attcgtcagg gccgcgatat tcttcacgcc tgggatgcca cctggaactc ggcgcaggcg
     3241 ctggataacg cactacagcc ggacagagca ggtcagtttg ccgacgcact ggagaaatac
     3301 gccgctggtc tggcaaccgc actcagccgt tctcctcaaa taacgcttga agaaacaccc
     3361 gcctcgcagg ccatcctgcc caccttatta aaacaggagc aacacgtctg ccagcttttc
     3421 gcccgcttgc cagactggac agccccggca ttaacgcccg ccaaggaaca ggcacaagga
     3481 gccacacaat gatcaatcgt caactttcac gtctgctgtt gtgcagcatt ctcggcagca
     3541 cgacgctgat ttccggctgt gccctggtac gtaaggattc tgcgcctcat caacagctca
     3601 aaccggaaca aatcaaactg gccgatgata ttcatcttgc cagctccggc tggccgcagg
     3661 cgcagtggtg gaaacaactc aatgacccgc agctggatgc gctgatccaa cggactctaa
     3721 atggttcaca caccctcgcc gaagcgaaac tgcgggaaga aaaagcgcag tcccaggccg
     3781 atttgttaga tgccggttca caattacagg tcgcagcgtt agggatgctc aaccgccaac
     3841 gcgtctcggc gaacggcttt ttaagccctt atgcgatgga tgcgccagca ctgggtatgg
     3901 acgggccgta ctatacggaa gccacagtcg gtttgtttgc cggactggat ctcgatttgt
     3961 ggggtgtgca tcgctcagcg gttgctgccg ccattagcgc gcataatgcc gcgctggcag
     4021 aaaccgcagc agtagagcta tcgctgacca cgggcgtagc gcagctttat tacagtatgc
     4081 aggccagcta tcagatgctc gatctgttag aacaaactcg cgatgtgatt gattacgcgg
     4141 tgaaagcgca ccagagtaaa gtggcgcacg gtctggaagc gcaagtgcct ttccacggcg
     4201 cgcgggcaca gattctggcg gtcgataaac aaattgctgc cgtcaaaggg caaatcaccg
     4261 aaacgcgaga atctctgcgt gcattgattg gcgcgggagc cagcgatatg ccggagatca
     4321 aaccggtggc attaccgcaa gtccagaccg gtattccggc gacactctct tatgagttgc
     4381 tcgccagacg cccggatctg caagccatgc gctggtatgt tcaggcgtca ttagatcagg
     4441 tggattccgc gcgggcgctg ttctatccga gctttgatat caaagcgttt ttcggcctgg
     4501 attctatcca cctggatacc ttattcaaaa aaaccagtcg ccagttcaac tttatcccag
     4561 gtctgaaatt gccgctgttt gacggtggac ggttgaatgc caatctcgaa ggcactcgcg
     4621 ccgccagcaa catgatgatt gaacgttaca accagtcagt actgaacgcg gtgcgtgacg
     4681 ttgccgtcaa cggcacacgt ctgcaaacgc tcaacgacga gcgagagatg caggctgaac
     4741 gcgtagaagc aacgcgcttc acccagcgcg cagccgaggc cgcctaccaa cgcggcttaa
     4801 ccagccgctt acaggccacc gaagcccggt tgccagtgct tgccgaagag atgtcattac
     4861 tgatgctgga cagccgccgg gtgatccaaa gcattcagtt gatgaaatcg ctgggcggcg
     4921 ggtatcaggc ggctcccgtc gtcgagaaaa aataaaatgt ctaccgcgtg atggctgtca
     4981 cgcggtattt cgtttcgtca cgtcaaaact gacgacagcc tgtttttcgt cagagttttg
     5041 aataaatagt gcccgtaata tcagggaatg accccaaata aaatgtggca taaaagatgc
     5101 atactgtagt cgagagcgcg tatgcgtgat ttgattaact ggagcgagac cgatgaaaaa
     5161 agtcgtcacg gtttgcccct attgcgcatc aggttgcaaa atcaacctgg tcgtcgataa
     5221 cggcaaaatc gtccgggcgg aggcagcgca ggggaaaacc aaccagggta ccctgtgtct
     5281 gaagggttat tatggctggg acttcattaa cgatacccag atcctgaccc cgcgcctgaa
     5341 aacccccatg atccgtcgcc agcgtggcgg caaactcgaa cctgtttcct gggatgaggc
     5401 actgaattac gttgccgagc gcctgagcgc catcaaagag aagtacggtc cggatgccat
     5461 ccagacgacc ggctcctcgc gcggtacggg taacgaaacc aactatgtaa tgcaaaaatt
     5521 tgcgcgcgcc gttattggta ccaataacgt tgactgctgc gctcgtgtct gacacggccc
     5581 atcggttgca ggtctgcacc aatcggtcgg taatggcgca atgagcaatg ctattaacga
     5641 aattgataat accgatttag tgttcgtttt cgggtataac ccggcggatt cccacccaat
     5701 cgtggcgaat cacgtaatta acgctaaacg taacggggcg aaaattatcg tctgcgatcc
     5761 gcgcaaaatt gaaaccgcgc gcattgctga catgcacatt gcactgaaaa acggctcgaa
     5821 catcgcgctg ttgaatgcga tgggccatgt cattattgaa gaaaatctgt acgacaaagc
     5881 gttcgtcgct tcccgtacag aaggctttga agagtatcgt aaaatcgttg aaggctacac
     5941 gccggagtcg gttgaagata tcaccggcgt cagcgccagt gagattcgtc aggcggcgcg
     6001 gatgtatgcc caggcagaaa gcgccgccat cctgtggggc atgggggtaa cccagttcta
     6061 tcagggcgtg gaaaccgtgc gttctctgac cagcctcgcg atgctgaccg gtaacctcgg
     6121 taagccacat gcgggtgtaa acccggttcg tggtcagaac aacgtgcagg gtgcctgcga
     6181 tatgggcgcg ctgccggata cgtatccggg ctatcagtac gtgaaagatc cggctaaccg
     6241 cgagaaattt gccaaagcct ggggcgtaga gagcctgcca gcgcataccg gttatcgtat
     6301 cagcgagctg ccgcaccgcg tggcgcatgg tgaagtgaga gcggcgtaca ttatgggcga
     6361 agatccgctg caaactgacg cggaactgtc ggcagtacgt aaagcctttg aagatctgga
     6421 actggttatc gttcaggaca tctttatgac caaaaccgcg tcggcggcgg atgtcatttt
     6481 accgtcaacg tcgtggggcg agcatgaagg cgtgtttact gcggctgacc gtggcttcca
     6541 gcgtttcttc aaggcggttg agccgaagtg ggatctgaaa acggactggc aaatcatcag
     6601 tgaaattgcc actcgtatgg gttatccgat gcactacaac aacacccagg agatctggga
     6661 tgagttgcgt catctgtgcc cggatttcta cggtgcgact tacgagaaaa tgggcgaact
     6721 gggcttcatt cagtggcctt gccgcgatac ttcagatgcc gatcagggga cttcttatct
     6781 gtttaaagag aagtttgata ccccgaacgg tctggcgcag ttcttcacct gcgactgggt
     6841 agcgccaatc gacaaactca ccgacgaata cccgatggta ctgtcaacgg tgcgtgaagt
     6901 tggtcactac tcttgccgtt cgatgaccgg taactgtgcg gcactggcgg cgctggctga
     6961 tgaacctggc tacgcacaaa tcaataccga agacgccaaa cgtctgggta ttgaagatga
     7021 ggcattggtt tgggtgcact cgcgtaaagg caaaattatc acccgtgcgc aggtcagcga
     7081 tcgtccgaac aaaggggcga tttacatgac ctaccagtgg tggattggtg cctgtaacga
     7141 gctggtgacc gaaaacttaa gcccgattac gaaaacgccg gaatacaaat actgcgccgt
     7201 gcgcgtcgag ccgatcgccg atcagcgcgc cgccgagcag tacgtgattg acgagtacaa
     7261 caagttgaaa actcgcctgc gcgaagcggc actggcgtaa taccgcttaa actcacgtta
     7321 aaagcggtga tattacccaa cgcctttgta tcaatccgga aacgactctc tgtttccgga
     7381 tttttttata catacctgcg cagtcaaacc agcctatcct ggttattagc gacgtcttct
     7441 cggttgttct tctattccag tcacgattgc aaatgagaat tatctttact caattctcat
     7501 cgcggcctaa cgtaataata ctttacattt gatgaaccaa atttcggtaa ggtgagaaat
     7561 catcgaccgt ttaactcgtt ctattaacgg gatattttgg cgcgattaat gcaacaaaac
     7621 cccgtctgat agaatattaa taacctcaaa gtaatttcag ggattgggaa gcatatgatt
     7681 aaaaaactat tacctttact ggttttaagc acaatttccg ccacaaccgt tgccgctaca
     7741 ccgcctaata cgttggttgt agcccagggg ctggatgata ttgtgagcct ggacccggca
     7801 gaagctaatg aactctcaag tattcagact gtaccaagtc tgtatcaacg cgtagtgcaa
     7861 ccggaccgta atgatccgac gaaaattact ccgattctgg cggaaagttg gcaggctgac
     7921 cccgcagcca aaacgctaac cataaaactg aaaagcgatg cgaaatttgc ctctggtaat
     7981 ccggtacgcc cggaagatgt gatttactct tatgtccggg ctgtcacact gaataaatcc
     8041 ggtgcgttta ttctcaatgt gctgggatgg cagccggaaa atatcgccag ccagttgaag
     8101 aaaatcgatg accataccgt ccaggtgcaa tggagtgccg acgtcagccc ggctctggca
     8161 ctgaatattc tctccacacc aatcgcctca attgttgacg agaagctggt tgcgccaaac
     8221 gccaaaaata acgactttgg taatgaatgg ctgaagatgc attccgctgg cagcggcgcg
     8281 tttaaaatgc gtacttacca accgcatcag gccatcgtga tggaagccaa cgccagctca
     8341 ccaaccggcg ccccgaaact gaaaagcgtc atcatcaaaa atgttcccga tccggcaaca
     8401 cgtcgcctgc tgatccaaca aggtgatgct gatatggctc gtgatctggg agccgatcaa
     8461 atcgatgcat tacagggtaa acctggcgta aaagtgatga gcattgcctc cgccgaacag
     8521 aactacctgg ccttcaatac cggtaacaag gataacccgc tgatgagtaa tcctgcgttc
     8581 tgggaggccg ctcgctggtt ggtcgattac gacggcatca ccaaaaatct cttaaaagga
     8641 caatatttta cccatcagag tttcctgccc gtgggctttc ctggagcact ggaagaaaca
     8701 ccgtttacct ttaatccagc caaagcaaaa gagatcctcg ctaaagccgg aatcaaagac
     8761 ccgcacttca cgcttgatgt cgaaaataaa ccgccattta ttaccatcgc gcagtcaatt
     8821 caggccagct ttgctcaggg cggtgtaaaa gttgatttgc tgccagccgc agggagtcag
     8881 gtctactctc gcgttcgcgc ccaccagcat cagggggcca ttcgtatgtg gttgcctgat
     8941 tattttgacg cacattccaa cgccagctct ttcgcctata acgatggcaa atccagcacc
     9001 gttgccgggt taaacggctg gaaaatcccg gaactgaaca aagaaacgct ggcggccatc
     9061 gctgaacctg atagcactaa acgtcttgat ttgtataaga aaatgcaaca agaactacaa
     9121 cgtagttccc cgtatgtctt tattgatcaa ggcaaaacgc aaattgtcat gcgtgataat
     9181 gtgcaggggt atcaacaagg gttgaatgcc gatatggtct ggtttgatca ggtaaccaaa
     9241 taaccctgta tgcaactcgc gtccagccat gttaccgggc gcggtaccag ggctggcctg
     9301 tattgcaggc cagccgctga tttatcactg tatggaaaga tcatgtctgt cgttttttcc
     9361 actcgcgcaa gatggcgagg caaacgccct ctgctcgcgc tgttgcaagg gctgtttacc
     9421 gttgctctga cgctactcgg cctgctgctg attacctttg cgctttcggc tctctcaccg
     9481 gtcgatcgcg tactacaaat cgttggcgat cacgccagcc agtccaccta tgatcaggta
     9541 cgccaccagt taggattgga tcagccgtta gccgtccagt tctggcatta cctgatgaat
     9601 ctggcacacg gcgatctggg catcgccagc tccaccgggc aaccagtact ccaggacttg
     9661 ctatcagcat tcccggcgac cattgaactg gcaacgttgg cgcttattgt cggtgctgtt
     9721 gtcggcgtca ttgcgggtgt actttgcgcc cgttatgtcg gttctccgct ggatttcacc
     9781 gtgcgaacat taactctact gggaaattcc gtccctgttt tttggcttgg tctgctgatg
     9841 ctggcgctgt tctacgccag actgcaatgg agtgccgggc cgggcaggct ggatgatatt
     9901 tatcaattca ccatagaacc ccgcagcgga tttgcgctga ttgatacgtg gctttctggc
     9961 gatcgcgagg catttaccaa tgcaatcaac catttgatac ttccggtttt attactggcg
    10021 tacttctcgc tcgccagtat tacgcgcctg actcgttccg cctgtcttgg cgaaatgaat
    10081 aaagaatata ttctgctggc gcgcgccaaa ggggccagcg agatgacaat tttgctacgt
    10141 catgttttac ccaacattcg cggcaccttg ctcaccgtta tcgccctcgc ctatacatca
    10201 atgctggaag gcgcggtact gacagaaacc gtcttttcat ggccaggtat tgggcgctac
    10261 ctcactacag cgctcttcgc gggtgatacc acagcaatca tgggaggaac gctgctgatt
    10321 ggcgtctgct ttgtgttgat aaataactta accgacctgc tggtccggct gaccgatccg
    10381 aggttacgct gatgccgatg tttctctttt tacgccgttt acgccattca cccgccgcgt
    10441 tttgcgggtt gataattatc ctgttattga tgctaattgc gctcttcgcg ccgtggctgg
    10501 cacctcacga tcctaactgg caggatgcgg cggcgcgatt acaagcaccg agtcgtcagc
    10561 actggctcgg cactgacagt tacgggcgag acctactttc acgtttaatc tacggcagcc
    10621 gcccggcact ggggctggtg gcattggtga caatcattac actcccggtc ggtctgctga
    10681 ttggcatttt agccgggtac tacggcggct ggctggaacg cgtgctgatg cgttttactg
    10741 acatagtaat gtcaatgccg cgtttaattc tggcttttgc ttttgttgcc atgctggggc
    10801 cggggctggt taacggcgca ctggcccttg cattaaccac ctggcctgct tatgcgcgtc
    10861 aggcacggag tgagatccaa cgtctgcgac acagtgatta tcttgccgcc gcagaaatga
    10921 tgggcatccg cggcaggcgt ctgctggctg gtcatatttt gccattgtgc ctgccatctg
    10981 ccattgtccg tctggcgctg gatttagcgg gtatcattct ggcggctgct ggtctgggtt
    11041 ttcttgggct tggtgctcgc ccgccaatgg cggaatgggg agccatgatc gccgacggta
    11101 tgcaggtcat ttttgatcaa tggtggattg ccgccgctcc cggcgcaatt atcttaattg
    11161 ccagtctggc ctttaatctg ctgggtgatg gcttgcgcga tgttctggag cctcaacatg
    11221 actgactcac gtcttagtat caacaatctc tgcgtcgatt atccggagtc ccgggtcgtc
    11281 aacaatgtca gttttacatt aggcaatgaa cgtctggcgc tggtcggtga gtcgggttca
    11341 ggtaagtcca tgaccgcccg cgccctgatg gggctggtgc gtaaaccggg tgtagtaacc
    11401 gcggacacac ttaacattct ggggcgtgat gcactcaccc ttaacgcgcg tggatggcaa
    11461 cagttgcgcg gtaacgatat cgcgatggta ttgcaagatc cgcgttacgc gcttaatcca
    11521 gtaaagacag taaaagcgca actggaagag gcgcttacgc tccatcaacg tctgaaccgc
    11581 cgcgagaaag aagagaaaat aaacaccgca attcaggctg tcggcctcaa tacgcgagta
    11641 ctgcaaagct atcctcgtga actttctggc ggcatggggc agcgagtgat gattgcaatt
    11701 gcgctcatca acgatccccg ggtattgatt gccgatgagc caacatcagc actagatgtg
    11761 cgcctgcgta atcagattct ggaactgctg gttacccagt gtgaacaacg tcagatggca
    11821 atgttgctga tcagtcacga cctgccatta gttgcccaat tttgccatcg ggtgctggtg
    11881 atgtatcagg gaaataaggt ggatgaaatg cacgctgctg cgctacctac agcaacgcat
    11941 ccttacacgc gcacactgtg gacttgccgc ccaaatgcac aaacttacgg gcagatgctg
    12001 ccgacgctgg acaggacggc aatgacgccg gagaaatacc atgacgattg ttgaaattaa
    12061 tcacttacag gtgacttttg ctgagaaaac cgcagtttct gccgccagtt tttcggttaa
    12121 tgccggagag acatttagtt taattggcga atcaggctgc ggaaaatcca cgattttgcg
    12181 cgtaattgct ggattacagc gcgactggca cggtcaggtg tcactgtttg ggcacaccat
    12241 caaaccagga atgcgttttc agggcgatct ccgccgcaat gtgcaaatgg tgtttcagga
    12301 tccctatgcc tcgttgcatc ccaatcatac tctgtggcga acgctggctg aaccactcaa
    12361 aattcgtggc gaaagagaaa tagaaaaacg cgtccagact gcactggaac aggttggctt
    12421 gcctttcgac gccgctcgtc gctacccaca ccagctttcc ggtggtcaac ggcaacgtgt
    12481 ggttattgct cgcgccctgt tgttacgacc acaacttctt ctgctggatg aacccacctc
    12541 ggcgttggat atgtcggtac aagcggaaat ccttaatttg ttgaatcaac ttaagctgga
    12601 acaccaaatg acatatctgc tggtcagtca cgatgccgat gtcatcgcgc atatgtctga
    12661 tcgagcggca ttgatgtccg agggaaaaat tcagcgattt tttgatcgcg acgccatgga
    12721 aaagggggaa catcggatgg attaaaaaac ctgacattgc attaattcat tctgctttca
    12781 ggtcttttta cagttgtttt tttgtccacc cgaacacttt atactgtctc tcccctacca
    12841 aacttcatta tcaaaatgaa aaaaattatc actttgatgt tgtttttgac attctttgcc
    12901 cacgcgaacg actccgagcc tggcagccag tatttaaagg cagcagaggc cggagaccga
    12961 cgcgcacaat attttcttgc cgacagctgg tttagctccg gcgatttgag caaagccgaa
    13021 tattgggcac agaaagccgc cgacagcggt gatgccgatg cctgcgcgct gttggcgcag
    13081 atcaaaatca ccaatccggt cagtctggac tatccacaag caaaagtgct tgccgagaaa
    13141 gcagcgcaag cgggcagtaa agaaggtgaa gtaacgctgg cgcatattct ggtaaatacg
    13201 caagcgggta aaccggatta tccaaaggcg atttcgctgt tagaaaacgc ctcggaagat
    13261 ctggagaacg actctgccgt cgatgcccaa atgctgcttg gtttgattta cgccaacggc
    13321 gtgggcatta aggccgacga tgacaaagca acctggtatt tcaaacgtag ctctgcgatt
    13381 tcccgaaccg gttattccga atactgggcg ggaatgatgt tcttaaacgg tgaagagggt
    13441 tttatcgaga agaataaaca aaaggcgctg cactggttga atctgagctg tatggaagga
    13501 tttgataccg gttgtgaaga gtttgaaaaa ttaactaacg gttaaggtag gcgcagcaaa
    13561 cgtcgcatca ggcattgatg tcggatgcgg cgtaaacgcc ttatccgacc tacaaaaatc
    13621 acgccaaatc aggctattgc gctgtctgac gtaggcctga taagacacgt cagcatcgca
    13681 tcagacattg atgccggatg cggcgtaaac gccttatccg acctacaaaa atcacgccaa
    13741 atcaggctat tgcgctgtct ggcgtaggcc tgataagacg cggcaagcgt cgcatcaggc
    13801 gttgatgtcg gatgcggcgt aaacgcctta tccgacctac aaaaatcacg ccaaatcagg
    13861 ctattgcgct gtctggcgta ggcctgataa gacgcgttaa gcgtcgcatc aggcgttgat
    13921 gtcggatgcg gcgtaaacgc cttatccgac ctacaaaaat cacgctacat caggctatta
    13981 ctcagtcagg catccacaca ttgccgggtg gatatccccc cggcaatctt caattactga
    14041 tctgctgttt tatcaaattt gcccaacatt tcacgctcgt aggccagcgc ttttttacgg
    14101 tcaaatttgt gttcccactt ggcaatcacc agcaccgcca gcgcattacc caccacgttc
    14161 agcgcagtac gcgccatatc gaggatacgg tcaacaccgg caataaacgc cagaccttcc
    14221 agcggaatac ctacgctacc cagcgttgcc agcagcacca caaacgacac gcccggcacg
    14281 ccagcaatcc ctttcgaggt caccatcagc gtcagcacca gaatgatttc ctgccagatg
    14341 gacaggtcaa tgccatacag ctgagcgatg aaaatagcgg caatactttg atacagcgtc
    14401 gaaccatcaa ggttaaaaga gtaaccggtc ggcaccacga aactggtgat cgacgccggt
    14461 gcaccgtagg cttccatctt ctcaataatt cgcggcagca cgctttcaga actggcagta
    14521 gagtacgcca gaatcagctc atctttcaga atacgaatca ggatccagac acttaacccg
    14581 cacaggcgcg ccacaattcc cagtacgacc agcgcgaaga acagaatggc gaaatgcacc
    14641 agcagcacca gtttcgccag tggccacaga gaagagaaac caaagttagc caccgtcacc
    14701 gcaatcagcg caaacacacc caccggcgca taacgcatca ccatgtgagt cactttaaac
    14761 atggtttcag agatggagcg gaaaacggtc accagcggtt cacgatgcgt cgcgggcagg
    14821 gatgaaagcc ccagaccaaa cagcaccgag aagaagatga tcggcagcat ttcgcctttc
    14881 gccatcgacg ccacgatgtt cgtcggcacc agcgacaaaa tcgtgcccat aatgccgtgg
    14941 gaactgcttt gtaccgcttc cgtagtgctc tgatatttcg agatatcgac ggtcgccagc
    15001 tgcgacatat ccaccccggc accgggctgg aagacgttcg ccagagtgat ccccaaaatg
    15061 atggcgacgg tggtgatcac ctcgaagtag ataatggttt tcgcaccaat acgcccgagc
    15121 tgtttggcat caccaacacc cgcgataccc accaccagcg tggagatcac aatcggcaca
    15181 acaatcattt tgatcagatg gatgaagata tcacccgccg gagagagcaa attgacgacc
    15241 agccagtcgc ggctgtcgct atggtagtgc aggtagcttc ccaggagaat gcccagcacc
    15301 atagcaaaca gaatctgcca ggccaggctg aattttatat ttttcatcag aataacttcc
    15361 tcaatggagc gccgttcccc gttcagaaac gcgagaacgt gacatactgc cagggcatga
    15421 attgtgttgc gttggtttgt agattttttt aacgcttatg atcagtatca tttgcgcggt
    15481 atgttgcgca accctttaac aacagagctt ttcgctgcat taatgcataa taacgcgagt
    15541 ttatggcagg attaatgaat aaccatttgt tatagaagga tttttatttg tttaatctgc
    15601 aataatactg attagtgatt atttttgatt atatgttcat tcgattattt tttatgcagc
    15661 tcaataacat aatcttcatc accagatgat taatctgatc tccgctgcaa caatttcgcc
    15721 atattaatcg actcgaccag ctgtgtccgg ttgatccggg gtgagttgag atccatcact
    15781 ttttgccata gttcgatggc ttgcgcgtaa ttcgcctgca taaacgcatc ggaagccagc
    15841 agcatcagag cggtgatttc gttagagtcc agcgcgaggg ctttgtcgat cattgcgcga
    15901 gcctggacgg tcatatgttg gctggcctgg taatacagca ccgtcgccag cgccgcatac
    15961 agttcagcgt tctcaccacg tagttgcaac gcctgacggt acgccagcag cgaattgctg
    16021 taatcgtttt gccacagata atactcgccc agtaacgccc actgttcgct gttttgtgga
    16081 ttagcacgga ttttatcctg caatgcctga agctgcgctt ccggggtttg ctggctggca
    16141 aactgatgca gcggatcgcg ctgacgctga tactccgcac gtaccgcctg ccattttgga
    16201 cttaacagat aactgccgac acagagaaat accatcaaaa tcgtgagtgt tgtcagcatt
    16261 ttcaccggta tttggggctg tttcatcgct tcgccctcac tcgccagagg atcagtgcca
    16321 tcagcagtaa caacactact ggcagcgccc acaacaccag agtctgaccc gttaacggtg
    16381 ggttatagcg aacaaaatct ccgtagcgtt cggtcatcca gccaatgatt tcgacttcac
    16441 ttttcccctc ttccaccatg gtgtaaacct gatggcgcat actgactgcc accggcgcat
    16501 tggattccag taagttctga ttctggcact gcggacaacg taactggctg gcaatattta
    16561 acgcctgttc ctgttgttgc ggattagcga attgccaggt gtctacaacc tgagcgcgcg
    16621 caaaacaggt aaataacagc agtagcgtga gaagcccttt attcatcgcg cttccttccc
    16681 cgccatccgc ttaacaatgc gcccgcaatc atcaacaatc ctccccccca gatccagcgc
    16741 acaccgcttt gtacatacaa acgaaatgcg taacgatccg ctccggtttt ctctcccatg
    16801 accgcatacc agtcatggat gccgttccag cgaatcgagg gttccatcat ttgctgacgg
    16861 cgtgcttcgt aaaaacgccg ctccggcgtt aattcaccaa tgcgttgctg atggtcaaac
    16921 agtgccacta tcgctttttc gctggtgtaa ttgcctttgg cttgcagatc gaggcgctca
    16981 aaacggaagg tgtatcctgc cagcgtcacc tgctgacccg gctgtaaatt caggctgatc
    17041 tcctgacggc tgacgctgga aaccacgatc cccgcggcaa ataacagcac gcccgcatgc
    17101 gccagcagcg tcggaagccg cgcgcgtttg ccagagacaa acgtcgccag cacaatcacc
    17161 accagcatca acagagcaaa cggtaacgtc gcgcggttaa aatacggcgc gccaacggag
    17221 aggcgtcccc agcccagcag gccgtaaatc atcggataaa gcgttcccac cagcacgatc
    17281 agtagcactg cgcaaaacag caacagcgta gcgaggatta acatttcccg cgataacccc
    17341 gaaaaacgca ccgccgggcc accgtcccgc gctcgccagc catacagagc cagagacgca
    17401 aggctaatca gtacaaacag gccgaacaac ggcacggcgc ggacgttatc cagcgcgaac
    17461 gcatgaaccg aaaccagaat gccagaacgg acaatcaacg tgcccagcag cgacagcatc
    17521 agagtaacta tcgtcagcaa cagcgaccag tggcggaaaa tcccccgctg gcgtgtcagg
    17581 gataaactgt gcagcagcgc tgtggcagaa agccagggta gtaaagaggc gttttccacc
    17641 ggatcccaga accaccagcc gccccagccc agttcgcaat aggcccacca ggaaccgagg
    17701 atgatccccg ctgttaatgc gctccagcca ggtagtgccc aacgccagca aattcgggcg
    17761 caggtaccat caaactcgcc gcgcagtaaa ctcgccagcg ccacgctcgc cgccaccatc
    17821 aaaccgccgt agccgagata aagcagcggt ggatgaaaga taagaccggg atgttgcagc
    17881 atcggattga gatcgcggcc ttcgattgct ggtggaaata tccgcacgaa gggatcggac
    17941 cacagcacca caaacagtag cagtgcggcg agcatgagag ataaaacggc tagcgtcagc
    18001 ggaaatagcg gatcggtttg ctgccggtaa tgccaggcaa acagcgcgct ccaggcggaa
    18061 agcagcagca cccaaagcaa cagcgaacct tcatgaccgc cccacaccgc cgccagtttg
    18121 agttcccacg acagcaggct atagctatgt tgggcgacat aaataaccga gaaatcgctg
    18181 atgagaaaac aatacgtcag tacgccaaag gcgagcagca ggagcgcgaa ctgcgccaga
    18241 atgccgatgc aagtgagtcg catcatggca ggccagcgca accgcactcc cgcgaaggcc
    18301 gtcaacggga tcaacacgtt gaccccgaga cttaacaaca acgccagaaa accgacttca
    18361 ggaaggaata cgtccagaaa ccacctctgt tctggcttac gccaccgtta actgcccggc
    18421 gtagagaatg aaaaagcgca gcatcaacac gccgaccagg ctggccccac atgccgccag
    18481 cacggcagga atgccggaac tgcgattgac ccacggtttg agcaacattg gcacaatcag
    18541 ccccagcccg gcgacaccaa gccagaacca ccacgtccag aaaccgccgc ccaatgccgc
    18601 caccagcgca cgcactttac cgtcatcgcc cagcgccaga ccgacaaaaa acgccaccag
    18661 caggaagatt tcaccccata ccacggggat ttccatacgg tgtacaaagt gcgcttccgt
    18721 ggaatgcggg ttactgcgtt ggcgtatcgc catggcgatc agcgccaccg ccgcaccgga
    18781 cgagatgccg gagaagagga acagcaccgg caggatcggg ttattgagga acggatacga
    18841 tttcagcgcc gacagcagaa agccggtata agcccccaac aacaccgcca gcaccagcat
    18901 caatgtttcc agtccgcgat gaacgggcgt cagcaggctc aagacctttt gcacgatccc
    18961 cagcttcggc aaccagcgtt gttgcagggc aagcaaatca tgttcaaaga ttttcgccag
    19021 ccacagcacc agcaccacca tgtaaagctg aaacagcatc acccccatcg acatcaccga
    19081 ggtaaaactg tagtggaaca tcagcttcca gaaggtccac ggtcttgtca ggtggaagac
    19141 gaggatcaac agaccgagga tcaccgcgcc aggcccgaca atcagcgtgg tgcgcagcaa
    19201 cgtactgtct gcaccgcctg cctgcgggta gaagcgacgt aacagcacgg ccagtgtcac
    19261 cagaccggca gaaataccaa tcaaaaacag gtagatggca atcggccagt cccacaccag
    19321 cgattcaaaa tgaaatgcgg aagtctgcgt cattggctca cctccccgta tttaaacggt
    19381 acgcggtaca gcttcggttt ggtgcccagc gccagcttgt agcggtaagt gggcttctgg
    19441 cgcagcagtt gcgaaatctc actgttggga tcgtccagat tgccaaacgt cagcgccttc
    19501 gtcgggcaag cttcaacgca cgcgggcagc ttaccggcct gcaaatgggt cttacggcag
    19561 aaatcgcatt tgtccgccgt cttcgtgacc ggatggataa agcgcacgcg gtacggacag
    19621 gcggcgatgc agtactgaca accgacgcag agatccggat taacatcgac aatcccactg
    19681 gcagcgtcgc gaaaagacgc accggtcggg cagacgtcaa cgcacggcgc atgatcgcag
    19741 tgctggcaag acttacggaa gaagcgatat ttcacatcag gaaattcgcc ctgcggctcg
    19801 ctacgaataa tcgtcaggcg cgagacgcct tccggcacct tgttcacttt ccgacaagca
    19861 tccatacagg cggtacagcc gatgcataac gactcgtcat gcaccatgcc gtaacgcacc
    19921 ccattgatat tcaacgtttt cgccaccacg cgccctgcgg tgccgctgac ggcggccagc
    19981 acaccgacgc cggtgagaaa ctggcgacga gaccaggtca tggctgctcc ttaagcaacg
    20041 gaacagacgc cgggttaaag ttcggattgg tgcgctgatc gctgtggcaa tcgacgcaaa
    20101 tcttaatccg tcctttgtca cttaacgtct gcatcgtatc ttgctgtgga tgcagggaat
    20161 ggcagctggc gcacgccact ttggttacgt ggacatcgtg cggccagaat gctttttgca
    20221 actgttccgg cagatggcag gacatacaga cgctgttctg ctctccaacc ttgtacatcg
    20281 gctcgttaaa gcgcatcaca tctttcaccc cttcgcggtg ttgcggtgat ggctggccgt
    20341 gacagttggt gcaggtgacc ggcagtttgt tattcgggtt gataacggaa gcatgtttgc
    20401 catgcatacc ttcggtatct ggcttatgac agtccagaca ggcggcatcc gggttacgct
    20461 gctgggtaac ttcgtagcga tcaccagatg cctgcgccgc aggggtagcg gtaattccgt
    20521 tcaggctcca caacaggccc gacgccagca ccccggcagt taataacgaa cgtaatacgc
    20581 tcatattcac tccattgtgt tttccgcccc ttgcgaggcg gaacggggtt attggcttaa
    20641 cagaccgttt ttacgtgcct gctcttccca ctgcgggatc accgttttga tgaagtcctg
    20701 cttctcggcc ttgatttgct ccatgttcag gccaatggcc tgctgggctt tctctttggt
    20761 cgagatatcc gggatctgga tttcatgggt aatgcctttg gtcgccagca ggcgcgccag
    20821 tttggtgcgt gcatccgccg ctttatccat cgccgtaccg agcatcctca gaccttcttc
    20881 cggtgcgtgc atatgaatgc cgtgggaagc gatcgccaaa tcccaacgcc actgggcatg
    20941 acggatatcg tcctgaatcg gcttcatttc ggcttccgtt gcgcctgcat ccagcgccgc
    21001 tttcgcttcg aagtgagcgt gaaccagttg atcttcaacc ttgattttca ggtcgttaat
    21061 cgactgctta cgttccgcga ccactttttg caaggcagct ttgtcctggg tatggcagtt
    21121 cgcacaagtc tgggcgaagt tatcaaacgg attaccaatt ttatggtcgg tgtagagttt
    21181 gccttcggcg ttctgcactt ttggcatatg gcaatcgata caggtcacgt tgtttttgcc
    21241 gtgaatgccc gctgtccagg tttcatattc cgggtgctgc gctttcagca ttggcgtttt
    21301 cgacagggag ttagtccagt cagagaaggc aattttgtcg taatactgct ccatattttc
    21361 gactttcatg ccgtcatccc acgggaattt aaccgctttg tttttgccgt cgaagtaata
    21421 ctccacatgg cactgaccgc aaaccatcga ttgctggtcg aaacgtccgg ctttctcaaa
    21481 aggtttacca atggcttcca tcgcgcgagc cgcatacgga cgggaaaggg ttaactccgg
    21541 tttgcctttg gcgaactctg gtgaggcggt gttatggcaa tcggcacaac ctaagttgtt
    21601 gacgatttcc gggccgccgc gcgcccattt accgtggaag tagccatctt cgccgtcttt
    21661 ctggatcaga cgcgccacat ccgggctttt acaactccag cacgccatcg gtagcggacc
    21721 atcttcagcg tttttcggcg caccggtacg caaggtttca cgcacatcgg tcacagcaaa
    21781 ggcatgtcca cgcggcttgt tgtaatcgcg cgagaaggga taccccgccc acaggatcac
    21841 cagccgtgga tcttccgcca gggcgtcaac acgctctgac tgttccgagg tagctttcca
    21901 ggagagatat tgatcgggat gctgcggggc aaaggtttca ttcttcgctt ccacagttac
    21961 aggtgttgcg ggagcagccg tttgttcagc gtgaacagaa gtgaaaaaga aaaaaggaat
    22021 caataagctg aagatacggc gtgcgtttat ttttatcctt gtcatagggc ttcatccgaa
    22081 ttgagccatt gttgcaatgg cggtttttat tgtttttcac gacagtaacc gcacctacac
    22141 tgtcatgaca ttgctcgccc ctatgtgtaa caaataacca cactatgaat gttgtcttta
    22201 atcaattgta agtgcatgta aaataccact ttagagttag tcggtatctt cctctttttc
    22261 aacaacatgc ataactgcat gttcctcaaa gaattaatca acttttgttg ctgaccttca
    22321 aaaattaccc tgccgtttat ttgcacaatt ctacttttgc gtgatctgtc gcccaaatac
    22381 taaacaaaac tgccaatacc cctacattta acgcttatgc cacatattat taacatccta
    22441 caaggagaac aaaagcatga gtcaaattca caaacacacc attcctgcca acatcgcaga
    22501 ccgttgcctg ataaaccctc agcagtacga ggcgatgtat caacaatcta ttgacgcacc
    22561 agataccttc tggggcgaac agggaaaaat tctcgactgg atcacaccgt accagaaggt
    22621 gaaaaacacc tcctttgccc ccggtaatgt gtccattaaa tggtacgagg acggcacgct
    22681 gaatctggcg gcaaactgcc ttgaccgcca tctgcaagaa aacggcgatc gtaccgccat
    22741 catctgggaa ggcgacgacg ccagccagag caaacatatt agctataaag agctgcaccg
    22801 cgacgtctgc cgcttcgcca ataccctgct cgaactgggc attaaaaaag gtgacgtagt
    22861 tgcgatttat atgccgatgg taccggaagc cgcggtcgcg atgctggcct gcgcccgcat
    22921 tggcgcggta cattcggtga ttttcggcgg cttctcgccg gaagccgttg ccggacgcat
    22981 tatcgactcc agttcacgac tggtgatcac ttccgacgaa ggtgtgcgtg ccgggcgtag
    23041 tattccgctg aagaaaaacg ttgatgacgc gctgaaaaac ccgaacgtca ccagcgtaga
    23101 gcatgtggtg gtactgaagc gtactggcgg aaaaattgac tggcaggaag ggcgcgacct
    23161 gtggtggcac gacctggttg agcaagccag cgatcagcac caggcggaag agatgaacgc
    23221 cgaagatccg ctgtttattc tctatacctc cggttctacc ggtaagccaa aaggcgtgct
    23281 gcacactacc ggcggttatc tggtgtacgc ggcgctgacc tttaaatatg tctttgatta
    23341 tcatccgggc gacatctact ggtgcaccgc cgatgtgggc tgggttaccg gacacagtta
    23401 tttgctgtat ggcccgctgg cctgcggcgc gaccacgctg atgtttgaag gcgtaccgaa
    23461 ctggccgacg cctgcccgta tggcgcaggt ggtggacaag catcaggtca atattctcta
    23521 taccgcgccc acggcgattc gcgcgctgat ggcggaaggc gataaagcga tcgaaggcac
    23581 cgaccgttcg tcgctgcgca ttctcggttc cgtgggcgag ccaattaacc cggaagcgtg
    23641 ggagtggtac tggaagaaga tcggcaacga gaaatgcccg gtggtcgaca cctggtggca
    23701 gaccgaaact ggcggtttca tgatcacacc actgcctggc gctaccgagc tgaaagccgg
    23761 ttcggcaaca cgtccgttct tcggcgtgca accggcgctg gtcgataacg aaggtaaccc
    23821 gctgaagggg gccaccgaag gcagtctggt gatcaccgac tcctggccgg gtcaggcgcg
    23881 tacgctgttt ggcgatcacg aacgttttga gcagacctac ttctccacct tcaaaaatat
    23941 gtatttcagc ggcgacggcg cgcgtcgtga tgaagatggc tattactgga tcaccgggcg
    24001 cgtggacgac gtgctgaacg tctccggtca ccgcctgggg acggcagaga ttgagtcggc
    24061 gctggtggcg catccgaaaa ttgccgaagc cgctgtggtc ggtattccgc acaatattaa
    24121 aggtcaggcg atctacgcct acgtcacgct taatcacggg gaggaaccgt caccagaact
    24181 gtacgcagaa gtccgcaact gggtgcgtaa agagattggc ccgctggcga cgccagacgt
    24241 gctgcactgg accgactccc tgcctaaaac ccgctccggc aaaattatgc gccgtattct
    24301 gcgcaaaatt gcggcgggcg ataccagcaa cctgggcgat acctcgacgc ttgccgatcc
    24361 tggcgtagtc gagaagctgc ttgaagagaa gcaggccatc gcgatgccat cgtaacccac
    24421 aattgtcgga tgcgctccga cctacatctg gcaacggctg taggtcggat aagatgcgcc
    24481 agcatcgcat ccgacaacaa gcgccggatg cggcgtgaat gccttatccg gcctacattc
    24541 ggcaagggtt acccaagcgt taaccttctc ccataaggga gcgggaatta aaacaatccc
    24601 tacattacct ctggagaatc tgtgatgaat ggtacgattt atcagcggat agaagacaat
    24661 gcgcatttca gggagttagt cgaaaaacgg caacggtttg ccaccatcct gtcgattatt
    24721 atgctggcag tttatatcgg ctttatttta ctgatcgcct tcgcgcccgg ctggctgggc
    24781 accccgctga atccgaacac cagcgtcaca cgcggtattc cagtcggtgt cggggtaatt
    24841 gtgatctcct ttgttctcac tggtatctac atctggcggg cgaacggcga attcgaccgt
    24901 cttaataatg aagtcctgca tgaggtacaa gcatcatgaa aagagttctg acggcgcttg
    24961 ccgccacact ccctttcgca gctaacgccg cggatgctat tagcggggcc gtagagcgcc
    25021 agccaacgaa ctggcaggcg attattatgt tcctgatttt cgtcgtgttt acgctcggca
    25081 ttacctactg ggcgtcaaaa cgcgtacgtt cgcgtaatga ctactacacc gcaggcggca
    25141 atatcaccgg ttttcagaac gggctggcga ttgccgggga ctatatgtcc gccgcctcat
    25201 tcttggggat ctccgcgctg gtgtttacct ccggctatga cggcttaatt tactcgctgg
    25261 gcttcctggt gggctggccg atcattctgt tcctgattgc cgaacgtctg cgtaacctcg
    25321 gtcgctacac ctttgccgat gtggcctctt accgtctgaa acaagggccg attcgtattc
    25381 tttcggcctg tggttctctg gtggtggtgg cgctttacct tatcgcccag atggtgggcg
    25441 caggtaaact gatcgagctg ctgtttggcc ttaactatca cattgcggta gtgctggtcg
    25501 gcgtgctgat gatgatgtac gtcctgttcg gcggcatgct ggcgaccacc tgggtacaaa
    25561 ttattaaagc cgtgctgttg ctgttcggtg ccagctttat ggcctttatg gtgatgaaac
    25621 acgtcggctt tagcttcaac aatctgttca gcgaagcgat ggcggtacac ccgaaaggtg
    25681 tcgacatcat gaagccgggc gggctggtga aagatcctat ctccgcgctc tctttggggc
    25741 taggactgat gtttggtacg gcgggcttgc cgcatattct gatgcgcttc tttacggtca
    25801 gcgatgcccg cgaagcacgt aagagcgtgt tctacgccac cggatttatg ggctacttct
    25861 acatcctgac ctttattatc ggctttggcg cgatcatgct ggtcggtgcg aatccggaat
    25921 ataaagacgc ggcgggccat ctgattggtg gtaacaacat ggcagcagtt cacctggcca
    25981 atgcggtggg cggcaacctg ttcctcggct ttatttcagc ggttgctttc gccaccattc
    26041 ttgcggtggt tgcgggtctg acgctggcgg gcgcatcggc ggtgtctcac gacctgtacg
    26101 ctaacgtctt caaaaaaggt gcgaccgaac gtgaagagct gcgggtatcg aaaatcaccg
    26161 tactgatcct cggtgtgatt gccattatcc tcggcgtgct gtttgagaat cagaacatcg
    26221 cctttatggt ggggctggcg tttgccatcg cggcgagctg taacttcccg atcattctgc
    26281 tttccatgta ctggtcgaaa ctgactaccc gtggcgcaat gctgggcggc tggttaggac
    26341 tgattactgc ggtggtgctg atgatcctcg gcccgacgat ttgggtacag atcctcggtc
    26401 acgaaaaagc cattttcccg tatgaatacc cggcgctgtt ctctatcagc gtggcattcc
    26461 tcggtatctg gttcttctcg gcaacggata attcagcgga aggtgcgcgc gagcgtgaac
    26521 tgttccgtgc gcagtttatc cgctcccaga ctggctttgg cgttgagcag ggccgcgcgc
    26581 attaatctct ccccttcccc ggtcgcttga tcggggaatt tcttcagaac atcatcctgg
    26641 ccaccagcgg cgaaaccaat accatcaata cacctgaaag catcatgacc aggcttgcaa
    26701 ctacgccttc ttgttgaccc agttcatacg accgcgcagt cccggcacca tgagatgccg
    26761 cgccgaatcc agcacctttc gccatccctt cgcgaataga gagacgtaaa aacaacacgt
    26821 cgccaatcgc catgccaaac acaccggtga ccaccacaaa cagcgccacc agatcaggct
    26881 gtccgccgag cgactggctc gctgccaaag caaatggcgt agtgaccgaa cgcaccgcca
    26941 ggctacgctg gatctcatct ggcagggtaa acaatcgcgc cagccacact gagctggtca
    27001 ctgccaccac cgttgccgtc agtacgcctg ccgtcaacga catccagtga cgcttaatga
    27061 tcgcccgatt gtcatacact ggtaccgcaa aggcgatggt ggccggacct aatagccata
    27121 gtaaccagtg cgcttcgcca atatagtttt gccaggaaat attgccaaaa accagcagca
    27181 taaccagtag cgtaggcgtc agcaccagag gcatcaatgg caatttacga aagcggcgat
    27241 aaaggcgttt gttaagaaaa tagataacta gcgtaattgc cagacagagc atacttagct
    27301 gaaaattagc cacggtttaa cctgcgcatt tcatagcgat agactttttc cactacccag
    27361 gcagtcgtgc ccagcaccat caccgtactc agcgcgatca cagcaaaaat acgccagcca
    27421 tccaccagta atagttgtgc atagttcacc acagccacca cggcagggac aaaaaacagc
    27481 aacatttcgg ccaatagcca acgcgccccg gctcgaaccc attgcagagg aagaatgcga
    27541 caaacaatca gcgccagcat caggatcatc cccaccaggt tggcaggcag cggcaaatgc
    27601 agccaggaga cgagatactg cgcaaaaata aataaacctg catacagcac aacctgaaaa
    27661 aatacctgga tagattgcac tacggcaggg gtaatgcggc gaagcgccac gggcatgaga
    27721 ggatatcctg aaaataaaac agaatggtaa gtatagagag cgctcgcccc tgactgaaat
    27781 gaattaaaat cattgcaggt atagtcaaag ggaatagtta tggatatcag aacgctgcgt
    27841 tattttgtcg aagtcgtgcg ccagcaaagc ttcacccgcg cagcggagaa gttgtttgtc
    27901 acccaaccaa ctatcagcaa gatgctgaag aatctcgaag atgagctgaa ctgtatattg
    27961 ttgatccgcg atggtcgtcg gctgcttctc actgatactg gtcgcgtcgt atttgagcgc
    28021 gggctggctt tactggctga gtttcggcaa ctggaagctg agcttagcga tatcaatcag
    28081 cttaaaaccg gcgttttgcg gctgggaatc ccgccgatgg ttgggatgtt gatggccggg
    28141 ccgattggcc tttttcgcca gcgttacccc ggcgtagaat tgaaaatttc ggagtttggt
    28201 ggtctgacgg tacaacaagc ggtgatgaac ggtgaactgg atatggcact gacagccctg
    28261 ccagtagaag aaagcggcct gacaacgtta tcgctgttta gtcatccact atgtgtactg
    28321 acgccacatt caggtaaatg gcttgaatgt gatgccgtct caccggagac attggcggaa
    28381 catcctctac ttatctataa cgaagatttt gccttaagta agcaattgat gaagttattc
    28441 gatgaacatg gcgttaagcc gagaattgca gttcgcagcg ggcaatggga ttttctcgcc
    28501 gcgatggttc aggccggtgt cggaatagcc atattgccgg aacccatttg ccagcgatta
    28561 gataaaaaca ccttaaaatg gctaccgctg gaaagcgaac taagctggaa attaggaatg
    28621 atttggcgtg agggcgttta cctttcccac tctgcccacg cgtggctgag ctgttgtgaa
    28681 ggatactggt taacgccaga gtaagtcggg ttggcgggct cgcccgccaa ccatgcagat
    28741 tactgatttt cctcaatcag caacgcttca agcaaatcga gatcgtgcag taatttttgc
    28801 agcgtttcgt tactgatctc ccgcgtggcg cgcaggtggt acagttcagc acgttcagaa
    28861 cgcaatgccg ccagacggaa gcgacgctcc aggttctctt ccaggattga actttctaca
    28921 tcattacgtc catcggcgcg acgacgcagg ttaccaatga cgcgagaact aacctctgtg
    28981 agcagctggt tatcgatatt ctcttcggta tccgccgcca aacgctcctc cattttctgg
    29041 atcgccacaa tcgccacttc tgccgttgcc gctcgtgcaa tacgttcctc tttcaattgt
    29101 tgcgaatggt ccgcgacttc tatgtgttgt agcagaatag gcaacatcac cacgccgaca
    29161 aacaacgaga agagaatgac gccagccgcc aggaacacca actcatagcg cgcagggaag
    29221 acgttaccat ccggcaagag aagcgggata gagagcacac cggccagagt gatcgcccca
    29281 cgcaccccgg cgaaagacgc gatcaggatt tctcgtgtag tccacgaacc aaactccatc
    29341 ggcttcttct tcaggaagcg gttgctgaac tttttcatcg tccacagcca gccgaaacgg
    29401 accagcatca gcgccgcata tatcagaata atatcggtaa acagcatcca gatttcgacg
    29461 ttaggatcga tttctgccgc catcagcgac gtctccagaa tccccggcaa ctgcagacct
    29521 aacagcagga acaccatgcc gttaaagaca aattccagca tcgcccaggt gctgtttgcg
    29581 cgcaggcgca ttgccagcgg cgcacggcgc atcacaccgg agcgggtgat ggtcatcccg
    29641 gcggcaaccg cagcgaggat gccggaaacg ccaatatgtt ccgcaatcag ataagaagcg
    29701 aatggcagca agaacagcag aacgatctgc gtcgcgggtt catcaccgcc ccagcggctg
    29761 aggaatcgca gcgagcgacc atacagccag ctcaccacaa aaccggcgag aataccgcct
    29821 attgccactt tcataaattc gaccgtcgca ccgccgacgg tgaagatcat tgtccccatc
    29881 gccactgcca cggcaaactt caacgacacc aggccggagg cgtcattcat caacgcttcg
    29941 ccctgcaaaa tgcccatgat ttttttcggg atgcgcccct cgccaacaat cccggagagc
    30001 gctacagcat cggtcggaga aagcaccgca gccagcgcaa aggcggggat cagcggaatg
    30061 cccggcacca cccagtaaat aaggaagcca atgccgacca cggtgaccac caccagcgcc
    30121 agcgcgaggc cgaaaatctc tcgcccatgt tcgagaaatt cacgggtcgg cgttttccaa
    30181 ccatcagcga acagcaacgg cgggataaac aagactaaaa agagttcagg atcaaactcc
    30241 acatgcaaac caaacgtcgg ccacgccagt agcgcaccga tggcgatttg cataagcgga
    30301 agcgggatct gaaagggcat gacacgagtg accaccccgg acagcgagac cacgagggtc
    30361 attatcagta tggtgaagaa gatttccatg cgttccctgt ttgcgatgtt ttttatgatc
    30421 tgagaaaggc gttatgcctg aattctcatt ttttcagaat atcgcaaaag ctcacacaat
    30481 gtgcggagaa aataaaaacg ggcagccatt gccacccgtt ttcagaatcc tatgtaagat
    30541 tagatagccc agccacccgc atagaaggtc accagcgcca cggcaataac gaccgtaccg
    30601 atgttcaact tgcgccattc gccggaaacc agacgaccaa tcaccagagt cgcgaagcca
    30661 atcatgatgc ctgttacgat gttacaggtc agcacgatga ataccgccgt aaccagaccc
    30721 gccatcgcat caacaaaatc agcaaagtcg attttcgcca cgttgctcag catcagcagg
    30781 ccaacgtaca tcagcgccgg agccgttgcg taccccggaa cgaggtaaga gagcggagag
    30841 aggaacagaa tcagcaggaa cagcacgcca acggtgatag ccgtcaaacc ggttttaccg
    30901 cccgccgccg tacccgccgc agactcgatg tataccgctg ccggagctgc acccaccagg
    30961 ccagaaaaaa cgctgctcat ggagtcggtg gtcagtgctt tcccgccgtc gatgatctgc
    31021 ccatctttat ccagcaggtt cgcctgaccg gcgacggcac ggatagttcc ggtggcatca
    31081 aatactgccg tcatcaccag tgccagaaca cttggcagga ctacaggatt cagcgcgccc
    31141 ataatgtcca ggctgcctat cagtgaattg ccgttttcat cgctcaatga aggcatggcg
    31201 aaaacgccgg agaaatggac gttaggatcg aagatcaaac cgacaattga gataccgata
    31261 atggtcagca gaatgccgcc agggactttc agtttttcca ggccgataat cactgccagc
    31321 cccaccaacg acatcatcac cggaaaggtc gtaaaatccc ccagcgcgac gggcagacca
    31381 tcaagcgggt ttttaatcac cagaccgaca ccattagcgg caatgagcag caggaacaga
    31441 ccgataccaa tccccgtgcc gtgcgccaca ccgtgcggca agttgcgcaa aatccagcta
    31501 cggatacccg tggcagaaat taccgtaaac agcacaccca tcaggaacac ggcacccagc
    31561 gcgacaggta cgctaatatg ttgccccagc accagactga atgcggtaaa cgccgtcaga
    31621 gagatggcgc aaccaatcgc caacggcaga ttagcccaca gacccatcac gatagaaccg
    31681 agtccggcaa ccagacaggt tgcaacgaaa actgccgcag gcgggaagcc cgctttaccc
    31741 aacatgcctg gaacgacgat aaccgagtag accatcgcca gaaacgttgt taacccggca
    31801 accacttcct gacggacagt gcttccacgt tgtgaaattt taaaccaggc gtcgagtgaa
    31861 ccgccggtac gcgctgatgg cgtagacata agaaaacatc ccctgagagt ttaattttcg
    31921 tcaagatgcg tggcggacaa tcccctgcca gcgaaacgtt atcttcctgc tccaggtttg
    31981 cgacaatttg ctgcgtcgca aaaaaagcaa acgtttagct ccgcgcatac aaaacgggtg
    32041 gtaaaaaaag caaacgatta tccggcgatc atagcggctt tttcaaccga agtttgctgc
    32101 ttttttctct tttattgtct tgacgatgaa aaaccaggca attgatgcgc aaacgttatc
    32161 gtcgatgcgc aagattgcag cgttatcgag ccgtataccg ttcaggattg cgataaaaaa
    32221 tcgtctgaga tgacaaaaat attgcggcta aaaagtgtac ttttacactg gcgaagaaac
    32281 gccggtaaca tacaattaaa gcatcaacac caaccggaac ctccaccacg tgctcgaatg
    32341 aggtgtgttg acgtcggggg aaaccctcct gtgtaccagc gggatagaga gaaagacaaa
    32401 gaccggaaaa caaactaaag cgcccttgtg gcgctttagt tttgttcatc ttccagtaag
    32461 cgtgcgccgg taccttcttc tcctaagcgg tcgcccgggt tacgcaacgg gcaatcactg
    32521 cgcgaaaggc agccacaacc aatacatcca tccagttcgt cacgcagcgc cactaaggta
    32581 tgaatgcgcc gatccaactc ttctcgccat tgggacgaaa gctgtttcca ctctttcgca
    32641 cttaacgtat gcccttctgg caacacgcca aacgcttcac gaatggttgc gagcggaatg
    32701 ccaatacgct gagcaatttt gataattgcg acatatcgca acacatcacg tttatatcgc
    32761 cgctgattgc cgctattacg gatactggta atcaaccctt tgctttcata gaaatgcagc
    32821 gccgataccg ccacaccgct gcgtttcgcc acttcgccgg gtgttagcag cgctttaatg
    32881 cggggtaatt tcttttccat aaatcgcttt acctcaagtt aacttgagga attatactcc
    32941 ccaacagatg aattaacgaa ctgaacactg aaaagaggca gatttatgtc ccatcagaaa
    33001 attattcagg atcttatcgc atggattgac gagcatattg accagccgct taacattgat
    33061 gtcgtcgcaa aaaaatctgg ctattcaaag tggtacttgc aacggatgtt ccgcacggtg
    33121 acgcatcaga cgcttggcga ttacattcgc cagcgccgtc tgttactggc cgccgttgag
    33181 ttgcgcacca ccgagcgtcc gatttttgat atcgcaatgg acctgggtta tgtctctcag
    33241 cagaccttct cccgcgtttt ccgtcggcag tttgatcgca ctcccagcga ttatcgccac
    33301 cgcctgtagt tttattgccc gcgcgttaat tcccgcgcgg gtaattgctc catccattgc
    33361 ataaacacct gcggcggcat cgccttcgcg aagaaccatc cctggcaata gcgcacgccg
    33421 cgtttgcgca gccagttaac ctgcgcctca gtttcgacac cttcagcaat cgtttttaac
    33481 cccaggctgt gcgccagctc gatgatgtgt tccgcaatca aatgactggt tttgtgggtg
    33541 gtcagcgtct caacaaacga tttatcgatt ttcaaaatat cgacattcaa tgatttaagg
    33601 ttatgcaagt tagagtagcc aataccaaaa tcatcaattg ccacttcgta accggccttg
    33661 cggaaagcca gaataatcgg cgtcattttg tcgacatcaa gaaatgcatg ttcagtcact
    33721 tcaaatttaa tttgctgcgg gcgcaccgca tgttgctctg ttttctgatt ggttcgcgct
    33781 atcaaccgtg aggtatgaaa atcggaggct gacaggttaa tagaaacata gcgatcggca
    33841 tgtgttgcca gatacgcgcc caaatcgcgg aagacattat caataacata atcagttacc
    33901 tgttcgatca tcccctcctt ttctgccagc ggaataaact ctgccggatt cattacttgc
    33961 ccctgctcac cgggccaacg taacaacgct tcagcgccga tacatttttc tgttttgata
    34021 tcgattattg gctggtaata aaggaaaagt tgatgttttt cgagggcgcg ttgcaatttg
    34081 cgtttgggag acaaatagtt ttgtcgaata cgtagccaga gtaatagcag aacaagactc
    34141 cccaaaatac cggcgggcaa cgcaaaaata agatgattat aaaaatgggt tataagacgt
    34201 tgatatgaag tcgcaacaat ggccgcaatt gggcgttttg tcgaataaac tgtcgcatat
    34261 aaatagccat ttcgttgtac ggttaaatca ttcaaacgaa tcagcggaga aaacgttgct
    34321 gccgaggcct cgttgcttaa cgagaaaaag gttttcgtca ccgtatcata cacaccccat
    34381 tgcaatgtcg gatcatcaga catcacttca ctccagaaga gagggttaat gaccgctaca
    34441 taattccccc gctgcatata ggtcatttta tagcctgaga aaaaaggcgt atcacggtaa
    34501 taatagatag aaacgttagg ttcacgctta taatcggccg gtgcaatcgt atagccattt
    34561 acagacgcta tcagcgatga gcataaaaaa tggttatcac gagcataaat caattcatta
    34621 atataaagat agccacgaat aatattcaac attcgctttt gatgggctgg agtgcaaact
    34681 tgcccctgat agcgttcagc tgcatcgctc actaaatctg cctgacgaat gaccagctca
    34741 gatttatcca acgccagctg agcaaaagtt cggagctgat tattcacttc tgattttgcc
    34801 caaaagaagg caatccatag cgacagaatg atgggaaaga gaactaaaaa gataatgccc
    34861 ggaaacgcca gtaattggtg tcgtgcacga tgactcattg ctatcaattc cctgcctgtt
    34921 tatacccggt tattgcaagg tgaaaccctg gctaccgacg tctttagata aatcttacgg
    34981 tataaatagc acttttgcct gatataaaat tgagaccttt ttaatcgtca ccaggatgac
    35041 gataattcat tgatcttaaa aattaatcac cttcaggaat gcagaggcgg cgggaagata
    35101 tacccttaat gccgctgaaa aaacacataa tctgtacggc aataaaagtc acggcctaat
    35161 ctggctaaca aacaaccaat tgtgatatag ttcacaaaat tcatgaaaca aacagagtgt
    35221 ttcatttttg tgttctgcaa gccccgcgat agccagagtg tatcacgcct cccgtgaaca
    35281 acgccgcgct gtccagggca tcagctcttt ttcgaggaat tgtttgatgg ctaccctcac
    35341 cactggcgtg gttcttcttc gctggcaact tcttagtgcc gtaatgatgt ttctggccag
    35401 cacgctcaac atccgttttc gtcgggctga ttatgtcggg cttgcagtga tcagcagcgg
    35461 tttgggcgta gtttccgcct gctggttcgc aatggggttg cttggcatca caatggcgga
    35521 tatcaccgcc atctggcaca acatcgagtc ggtgatgata gaagagatga atcagacacc
    35581 gccacaatgg ccaatgattt tgacttgata tgtagaagcc tccataacgg aggcttcttt
    35641 tttatggctg gcagatgctt taatcatcca ccttaaaaca atatacccta ttgttttaaa
    35701 gacaaatcag aacggaatat cgtcatcaaa gtccatcggc ggctcgttag acggcgctgc
    35761 cggagcggac tgctgcgggc gagactgcgc gccgccgctg aactgattgc caccctgcgg
    35821 ctgctgaggc tgaccccaac cgccctgcgg ctgaccacca ccgatattgc cacctgcagg
    35881 agcgccacca ccctgacgac cacccagcat ctgcatggtg ccgccaacgt tcaccacgac
    35941 ttctgtggta tagcgatcct gaccggattg atcggtccat ttgcgggtac gcagctgacc
    36001 ttcgatataa acctgagaac ctttacgcag atattcgctg gctacttctg ccagtttgcc
    36061 gaacagcaca acgcggtgcc attcagtctg ctctttcatc tcgccggtgg ctttatcacg
    36121 ccaggattcg gaagtagcca gcgtaatgtt ggcaactgcg ccaccatttg gcatgtagcg
    36181 tacttccggg tcctgaccca gattaccaac gagaataacc ttgtttacgc ctctgctggc
    36241 catgttcgtg tctcctgaaa aaaaatcgtt ctgaataagt gtaaacgcgc gattgtacca
    36301 ttaccaatag cgcttttact atgttgtgac ctcggttccg ggaaacaaac ctggccagac
    36361 attgttacac aacactccgg gtaatgcatt ccaatactgt atattcattc aggttaattt
    36421 gtgtcataat taaccgtttg tgatcgccgg tagcaccatg ccaccgggca aaaaagcgtt
    36481 taatccggga aaggtgaatg gataagatcg aagttcgggg cgcccgcacc cataatctca
    36541 aaaacatcaa cctcgttatc ccccgcgaca agctcattgt cgtgaccggg ctttcgggtt
    36601 ctggcaaatc ctcgctcgct ttcgacacct tatatgccga agggcagcgc cgttacgttg
    36661 aatccctttc cgcctacgcg cggcagtttc tgtcactgat ggagaagccg gacgtcgacc
    36721 atattgaggg gctttctcct gccatctcaa ttgagcagaa atcgacgtct cataacccgc
    36781 gctctacggt ggggacaatc accgaaatcc acgactattt gcgtctgctg tacgctcgcg
    36841 ttggtgagcc gcgctgcccg gaccacgatg taccgctggc ggcgcaaacc gtcagtcaga
    36901 tggtggataa cgtgttgtcc cagccggacg gcaagcgtct gatgctgctc gcgccaatca
    36961 ttaaagagcg caaaggcgaa cacaccaaaa cgctggagaa cctggcaagc cagggttaca
    37021 tccgtgctcg tattgatggc gaagtctgcg atctttccga tccgccgaaa ctggaactgc
    37081 aaaagaaaca taccattgaa gtggtggttg atcgcttcaa agtgcgtgac gatcttaccc
    37141 aacgtcttgc cgagtcgttt gaaaccgcgc tggagctttc cggtggtacc gcggtagtgg
    37201 cggatatgga cgacccgaaa gcggaagagc tgctgttctc cgccaacttt gcctgcccga
    37261 tttgcggtta cagtatgcgc gagctggaac ctcgcctgtt ttcatttaac aacccggcgg
    37321 gagcctgccc gacctgtgac ggacttggcg tacagcaata tttcgatcct gaccgcgtga
    37381 tccagaatcc ggaattatcg ctggctggcg gtgcgatccg tggctgggat cgccgcaact
    37441 tctattattt ccagatgctg aaatcgctgg cagatcacta taagttcgac gtcgaagcgc
    37501 cgtggggcag cctgagcgcg aacgtgcata aagtggtgtt gtacggttct ggcaaagaaa
    37561 atattgaatt caaatacatg aacgatcgtg gcgatacctc cattcgtcgt catccgttcg
    37621 aaggcgtgct gcacaatatg gagcgccgtt ataaagagac ggaatccagc gcggtacgtg
    37681 aagaattagc caagtttatc agcaatcgtc cgtgcgccag ctgcgaagga acccgtctgc
    37741 gtcgggaagc acgccacgtg tatgtcgaga atacgccgct gcccgccatc tccgacatga
    37801 gcatcggtca tgcgatggaa ttcttcaaca atctcaaact cgcaggtcag cgggcgaaga
    37861 ttgcagaaaa aatccttaaa gagatcggcg atcgtctgaa attcctcgtt aacgtcggcc
    37921 tgaattacct gacactttcc cgctcagcag agacactttc cggcggtgaa gcccagcgta
    37981 ttcgtctggc gagccagatt ggtgcaggcc tggttggcgt gatgtacgtg ctggatgagc
    38041 cgtctatcgg cctgcaccag cgcgataacg agcgcctgct gggtacgctt atccatctgc
    38101 gcgatctcgg taataccgtg attgtggtgg agcacgacga agacgcgatt cgcgccgctg
    38161 atcatgtgat cgatatcggt ccgggtgcgg gtgttcacgg cggtgaagtc gtcgcggaag
    38221 gtccgctgga agcaataatg gcggtgcctg agtcgttgac cgggcagtac atgagcggta
    38281 aacgcaagat tgaggtgccg aagaaacgcg ttccggcaaa tccggaaaaa gtgctgaaac
    38341 tgacgggcgc acgcggcaac aacctgaaag acgtgacgct gacgctgccg gtgggtctgt
    38401 ttacctgcat taccggagtt tcaggttccg gtaaatcaac gctgattaac gacacactgt
    38461 tcccaattgc ccaacgccag ttgaatggtg cgaccatcgc cgaaccagca ccgtatcgcg
    38521 atattcaggg gctggagcat ttcgataaag tgatcgatat cgaccaaagc ccaattggtc
    38581 gtactccgcg ttctaacccg gcgacctata ccggcgtgtt tacgcctgtg cgcgaactgt
    38641 ttgcgggcgt accggaatcc cgtgcgcgtg gttatacgcc aggacgtttc agctttaacg
    38701 ttcgcggcgg acgctgcgaa gcctgtcagg gcgacggcgt gatcaaagtg gagatgcact
    38761 tcctgccgga catttacgta ccgtgcgacc agtgcaaagg caaacgctat aaccgtgaaa
    38821 cgctggagat taagtacaaa ggcaaaacca tccacgaagt gctggatatg accatcgaag
    38881 aggcgcgtga gttctttgat gcggtgccag ctctggcacg taagctgcaa acattgatgg
    38941 acgttggtct gacgtatatt cgtctgggtc agtccgcaac cacactttct ggtggtgaag
    39001 cccagcgcgt gaagctggcg cgtgagctgt caaaacgcgg caccgggcag acgctgtata
    39061 ttctcgacga gccgaccacc ggtctgcact tcgccgatat tcagcaactg ctcgacgtac
    39121 tgcataaact gcgcgatcag ggcaatacca ttgtggtaat tgagcacaat ctcgacgtga
    39181 tcaaaaccgc tgactggatt gtcgacctgg gaccagaagg cggcagtggg ggcggcgaaa
    39241 tcctcgtctc cggtacgcca gaaaccgtcg cagagtgcga agcttcgcat acggcgcgct
    39301 tcctcaagcc gatgctgtaa tcgttaaggc cgctttctga gcggccttct tctttcagag
    39361 ttgcaccagc aatttacgtt tttcttccgg cagcaaattc accgcctgct gataagacgc
    39421 atccaccaga taatagattt gcgaatccgg cagcgatccg tcgagataca cggtgctcca
    39481 gtgtgctttg ttcagatggc ggcttggacg cacatcgctg tgctgctgac gtagcagctc
    39541 cgccagctcc gggctggttt tcagcgaaac agctgggcga ttttctactt ctttcaccat
    39601 cgcaaacagc acatcttcca ctttgatctg cgtcgctttc cagtcgttat gcacgctctg
    39661 ttctgcgcct ggttttgcca tgcaatattg tagcaactcc aaaatggtca ttttttactc
    39721 cccttgaagt gtcgcgatga tgcgacgcga tccgccgtgg atgcgatgtt cccccagcca
    39781 gatgccttgc caggtgccgg tctgaatacg ccctttatgc accggcaata caagcgatgt
    39841 tcccagcatt gaggatttga tatgagaagg catatcgtct gctccctcat agtcatgctc
    39901 ataatttccg ttgtcgggaa cggcgcggag gaaaaaacgc tccatgtcgt ggcgtacggt
    39961 gggatcgcag ttctcattaa gtgtcagaga ggcggaggta tgttgcagca acagatgcag
    40021 taaaccgatg ttaacgcgcg gcatatcagc cagctgattc agaatttcat ccgttaccag
    40081 atgaaaccca cgagatttgg cgctaagcgt gagcgtcttt tgataccaca tgtgctgctc
    40141 cttgataaaa ctctcttaat cagtttgcag caagacagcg aaaggataaa ggtgtgatta
    40201 aaaaaacagc attcgggaga gtattacgct ctcccgctct gtcagtattc tgaattgacg
    40261 atcacctctt caccaaacgc acccgcttgt ggcaagggtt tgtaggtaga gttggaggcg
    40321 cgcagaatgc ggataccacg agcgccaaca tcgcgtgcgg cggtaatatc gttatcggaa
    40381 tcaccataaa aaattcggat atttttatcc tgcagccatt gcgattttgt attttgacct
    40441 ggtttatcgc ccgcaaagat caccggattc atgttggtgg caggaatatg aaaattatcc
    40501 gccagcgttt ttgaaaccgt ttctgttttg gtcgggctac gaccagtcac aaagaagatc
    40561 gcgtcaccgc ggcgtacatg catatcaatc agctggcgag cgacctcttt tggaatgctg
    40621 aattcatccc agccattgtt cattttttcc cagaacacag gatttttcag ataatcttcg
    40681 ctttctggtg agaaggtttt tttgccgcgc cagaaacccg gactggaaaa aagtaccgta
    40741 tcatcgatat caaaccccac cgccattggc ggacgtcctg cgaggctatt ttcaatttgt
    40801 gcaaccgaaa cccaatgaat tggtgcctgt tcagcgagtt tggctacgtt agtacccgga
    40861 ttaagcggtg aaggagatga ggccagggca acagcggaac tgtttagagc gaacaataag
    40921 caaacggcac tcaatgcctg tgtgatcttg cgcatatttt tccctaaata gtcagtaagt
    40981 tgaaacttat tattgtgcgt ttgttgaaaa aaccatctga ccataacgcc aaccgcaggg
    41041 gaaaggaagg attatctgcg gatttgtcac ataaaaagag catgatcaca tttggaatac
    41101 ctgtgcgata aaccacacat tgccacggtt attctgctta cacattcaca caatggcact
    41161 cttttggttc tcgcaaacat tgttcaggga atatactgat gataaatata aatgcattca
    41221 atggatgatg aatgaaaata tcgtggaatt atatatttaa gaacaaatgg cgatttcaca
    41281 ttacaagcat ttcacttttt cttatcatgc tcgcggtttc aatcgctttt ttgcacttgc
    41341 gttttaatac cttgtccggt accgataaaa tgcggcttga aatgtataag tccacattat
    41401 attccaccat cgagcaattt tatgttttac cctatatgct ctcaacagac catatcatcc
    41461 gtcaggcggt aattacgcct gacgatatga cgtccagcga actcaatcaa cgaattgcac
    41521 atttcaatac tcaactcaaa accgcagcaa tatttattct ggatacccaa ggtaaggcca
    41581 tcgcttctag taactggcag gaccccggca gctatgtagg gcaaaattat agctatcgcc
    41641 cctattataa acacgccatg tctggcttaa atggacgctt ttacggtatt ggtagcacta
    41701 cgaatacacc gggattcttc ctctctacaa gtataaaaga taaaggaaaa attgtcggtg
    41761 ttgtagtagt aaaaataagt cttaatgaaa ttgaaaaagc atgggccgaa ggtcctgaaa
    41821 atattatcgt gaatgatgaa catgggatta tatttttaag ttcaaaatcg ccatggcgaa
    41881 tgcgaacact gcaaccgtta cctgttcagg caaaacaaaa actacaatct acccgccaat
    41941 atagtctcga caatctttta ccggcggatt attatccctg ttataccgtg agcaatttta
    42001 ctttcctgaa agataaaaaa gaacaactct gtttattccc gcaatattat acgcaacaaa
    42061 tagccattcc agaatttaac tggaaaatga caattatggt ccccttagat aacctgtact
    42121 ggtcatgggc tatttcgtta gtcattacac taattattta cctgctgttt ttgttattta
    42181 ttaaatactg gagaatgcga tctcatgcac aacaattatt aacactggcg aatgaaacat
    42241 tagaaaaaca ggttaaagag cgtacatctg ccctggaatt gatcaatcaa aaattaatac
    42301 aggagataaa agagcgcagt caggctgaac aagtattaca aattacgcgt agtgaactgg
    42361 cagagtccag caaactggcg gcgcttggac agatggcaac cgaaattgcc catgaacaaa
    42421 atcaaccgtt agccgccatt cacgcactta ctgataacgc gcgtactatg ctaaaaaaag
    42481 agatgtatcc acaggttgaa cagaatctga aacacattat ttccgtgatt gagcggatga
    42541 cgcagctcat ttccgaactt aaagcatttg cctcgcgcca tcgcgtacct aaaggttctg
    42601 ccgatgtcat caaagtgatg tatagcgccg tggcgttact taatcacagc atggagaaaa
    42661 ataacattga gcgacgaata aaagccccat ccatgccgtt atttgtcaat tgcgatgaac
    42721 tcggtcttga acagatattc agtaatttaa ttagcaacgc cttagattct atggaaggta
    42781 gctcttacaa acgactggat atcgccattc gccaggcaaa taacaaagtt attattacca
    42841 ttaaagacag cggtggcggt tttgcacctg aagttgtcga tcgcatattt gaaccatttt
    42901 ttaccactaa acgtagagga atggggttgg gactggcaat agtcagcgaa attgtccgaa
    42961 attcgaacgg cgcactccac gccagtaatc atcctgaagg cggcgcagta atgacattaa
    43021 cctggcctga atggggagaa aaacatgaat aa
//
LOCUS       DAFGPF010000031        42152 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFGPF010000031 DAFGPF010000000
VERSION     DAFGPF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42152
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.031"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            40..114
                     /locus_tag="LSX49_001888"
     tRNA            40..114
                     /locus_tag="LSX49_001888"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72..74,aa:Gln,seq:ctg)
     gene            152..226
                     /locus_tag="LSX49_001889"
     tRNA            152..226
                     /locus_tag="LSX49_001889"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:184..186,aa:Gln,seq:ctg)
     gene            complement(381..1556)
                     /gene="ubiF"
                     /locus_tag="LSX49_001890"
     CDS             complement(381..1556)
                     /gene="ubiF"
                     /locus_tag="LSX49_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HBL7168310.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFTVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVVFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPTSLTALHRHNDLQELELKGGETILAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPARIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLIRRHAL
                     QYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFMMQSGMDLFYAGFSNNLPPLRFVRNLGLMAAERAGVLKRKALKYALGL"
     gene            1702..3126
                     /gene="miaB"
                     /locus_tag="LSX49_001891"
     CDS             1702..3126
                     /gene="miaB"
                     /locus_tag="LSX49_001891"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBL7168311.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            3279..4319
                     /locus_tag="LSX49_001892"
     CDS             3279..4319
                     /locus_tag="LSX49_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415193.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBL7168312.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESV
                     PEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREEQEQK"
     gene            4316..4783
                     /gene="ybeY"
                     /locus_tag="LSX49_001893"
     CDS             4316..4783
                     /gene="ybeY"
                     /locus_tag="LSX49_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBL7168313.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEAIETEIMLALGYEDPYIAEKE"
     gene            4873..5751
                     /gene="corC"
                     /locus_tag="LSX49_001894"
     CDS             4873..5751
                     /gene="corC"
                     /locus_tag="LSX49_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HBL7168314.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            5776..7314
                     /gene="lnt"
                     /locus_tag="LSX49_001895"
     CDS             5776..7314
                     /gene="lnt"
                     /locus_tag="LSX49_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HBL7168315.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSTAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYVQWFTPQP
                     EKTIQVSMVQGNIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLITGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSLNGIQLTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYSRTGNWPLWVLTALFGFAAVLMSLR
                     ARKR"
     gene            complement(7441..9318)
                     /locus_tag="LSX49_001896"
     CDS             complement(7441..9318)
                     /locus_tag="LSX49_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL7168316.1"
                     /translation="MSASSVKPLNVQLPAITLILFALCVGIFCYLAQWMSYEEVDQSA
                     LIHLGANVASLTLSDESWRLLSSVFLHSSFSHLLMNMFALLVVGTVAERILGKWRLLI
                     IWLFSGIFGGLISACYALRESEQIVISVGASGAIMGIAGAAIATQLASGAGTHHKNQR
                     RVFPLLGMVALTLLYGTRQTGIDNACHIGGLIAGGALGWLSARLVGQNRLVTEGGIIV
                     AVTLLLTGTIWLVQQQIDESVLQVRQSLREAFYPQEIEQERRQKKQQLVEERNALRET
                     LSAPVSREQASGDLLAEIADIHDMAISRDANTLYAAIENTNSIVVFDLGQKKILHTFT
                     APIAKEKSVKHCGGCKDQGVRSLALSPDETLLYATSFEANALSVINVATGEIIQSITT
                     GAHPDSLILSRDGTKAWVMNRTSNSVSAIDLVAYQHVADIPLEKYDGTGMSGKPGAWV
                     MALSPDEKTLLVPGAGRGNIVRINTITHQKEDFPAGDARGVVSAMGFRPKNGEIIFAD
                     SQGISRIRAEDQQASIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILLNINAGQ
                     IIGVYPASYVNHLRFSADGRKIFVMAKNGLIQLDRESSLDPQAIIRHPQYGDVACIPE
                     P"
     gene            9772..10680
                     /gene="gltI"
                     /locus_tag="LSX49_001897"
     CDS             9772..10680
                     /gene="gltI"
                     /locus_tag="LSX49_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HBL7168317.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPAAGNTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNAERQKQAAFSNTIFVVGTRLLTKKGGDIKDFADLKGKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            10850..11590
                     /gene="gltJ"
                     /locus_tag="LSX49_001898"
     CDS             10850..11590
                     /gene="gltJ"
                     /locus_tag="LSX49_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HBL7168318.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMDLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAFIMLVMTLVERKVRLPGNMGGK"
     gene            11590..12264
                     /gene="gltK"
                     /locus_tag="LSX49_001899"
     CDS             11590..12264
                     /gene="gltK"
                     /locus_tag="LSX49_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HBL7168319.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            12264..12989
                     /gene="gltL"
                     /locus_tag="LSX49_001900"
     CDS             12264..12989
                     /gene="gltL"
                     /locus_tag="LSX49_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HBL7168320.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDS
                     PKDAFFDNPKSDRAKDFLAKILH"
     gene            13107..14042
                     /gene="rihA"
                     /locus_tag="LSX49_001901"
     CDS             13107..14042
                     /gene="rihA"
                     /locus_tag="LSX49_001901"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HBL7168321.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVASGAVKPLMRNLIIADNVHGESGLDGPALPEPAFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            14126..15796
                     /gene="hscC"
                     /locus_tag="LSX49_001902"
     CDS             14126..15796
                     /gene="hscC"
                     /locus_tag="LSX49_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HBL7168322.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVNASAGDNFLGGEDFTHMLVDEVLKRA
                     EVAKTTLNDSELAALYACVEAAKCSNQSPMHIRWQYQDEMRKCEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRNEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGTYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASDYLAIEIP"
     gene            complement(15856..17307)
                     /gene="djlC"
                     /locus_tag="LSX49_001903"
     CDS             complement(15856..17307)
                     /gene="djlC"
                     /locus_tag="LSX49_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HBL7168323.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLARLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAATEHEILRVFRALLDSENDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAIAIEARYLSLNCASLLAERLNWHSFNDCEGIDEEEREAFLEAI
                     QAGDCFDFLSLLEYPVALQNQTVEYYFSLERCCRYHPDYVTAFLAMEGPWFIPDDAKL
                     HRKLLRWYSSVQTGMAELIPVAQQWQAEEPESEDARYYQCAQRLYCGEGESLLADLCA
                     YRESYPSTQADNLLLQWSKRHCPDYFALLVMVIEARSMVDAQGKPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEQDSPLLDLYRVAEQVVL
                     EAFPKQEMLARLDARLERGEAHPLETIITRMLLTKVKLEPEDEDVDEPTPENHEEIND
                     EDEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(17304..18011)
                     /locus_tag="LSX49_001904"
     CDS             complement(17304..18011)
                     /locus_tag="LSX49_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HBL7168324.1"
                     /translation="MNKEEQYLLFALSTPMEILNQGCKPAHDSPKMYTGIKEFDLSSS
                     WGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSSPEEWKALIAGGSERGLIYTQFV
                     AQTAMCCGEGGIKAWDYVRMGFLSRVGVLNKWLTEDESLWLQSRVYIRAHHYYHSWMH
                     YFSAYSLGRLYWQSSQCEDNASLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQP
                     LTVQPECPVTLKDVSDL"
     gene            18113..18667
                     /locus_tag="LSX49_001905"
     CDS             18113..18667
                     /locus_tag="LSX49_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBL7168325.1"
                     /translation="MNKKLMYIFAIFIVAAITCISQPKKTTLRDKAMANYAFDYLSSP
                     GSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRA
                     QSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQ
                     KWLKLAAKQHYKNAERLLAGLSAH"
     gene            18807..19142
                     /locus_tag="LSX49_001906"
                     /pseudo
     CDS             18807..19142
                     /locus_tag="LSX49_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706566.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
     gene            complement(19212..19694)
                     /locus_tag="LSX49_001907"
     CDS             complement(19212..19694)
                     /locus_tag="LSX49_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HBL7168326.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            19929..22511
                     /gene="leuS"
                     /locus_tag="LSX49_001908"
     CDS             19929..22511
                     /gene="leuS"
                     /locus_tag="LSX49_001908"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBL7168327.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEY
                     KEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            22526..23107
                     /gene="lptE"
                     /locus_tag="LSX49_001909"
     CDS             22526..23107
                     /gene="lptE"
                     /locus_tag="LSX49_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HBL7168328.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            23107..24138
                     /gene="holA"
                     /locus_tag="LSX49_001910"
     CDS             23107..24138
                     /gene="holA"
                     /locus_tag="LSX49_001910"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBL7168329.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAA
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMSEALNRLSQPQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            24140..24781
                     /gene="nadD"
                     /locus_tag="LSX49_001911"
     CDS             24140..24781
                     /gene="nadD"
                     /locus_tag="LSX49_001911"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBL7168330.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSMQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            24805..25416
                     /locus_tag="LSX49_001912"
     CDS             24805..25416
                     /locus_tag="LSX49_001912"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HBL7168331.1"
                     /translation="MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLHD
                     VSFDLVLCSELERAQHTARLVLSDRQHPVHIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQQAIPTNGEGFQAFSQRVERFIARLSEYQHYQNILVVSHQGVLSLLIARL
                     IGMPAESMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA"
     gene            25676..25993
                     /gene="rsfS"
                     /locus_tag="LSX49_001913"
                     /gene_synonym="rsfA"
     CDS             25676..25993
                     /gene="rsfS"
                     /locus_tag="LSX49_001913"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBL7168332.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            25997..26464
                     /gene="rlmH"
                     /locus_tag="LSX49_001914"
     CDS             25997..26464
                     /gene="rlmH"
                     /locus_tag="LSX49_001914"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBL7168333.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            26495..28396
                     /gene="mrdA"
                     /locus_tag="LSX49_001915"
     CDS             26495..28396
                     /gene="mrdA"
                     /locus_tag="LSX49_001915"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HBL7168334.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            28399..29511
                     /gene="mrdB"
                     /locus_tag="LSX49_001916"
                     /gene_synonym="rodA"
     CDS             28399..29511
                     /gene="mrdB"
                     /locus_tag="LSX49_001916"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HBL7168335.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            29522..30610
                     /gene="rlpA"
                     /locus_tag="LSX49_001917"
     CDS             29522..30610
                     /gene="rlpA"
                     /locus_tag="LSX49_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HBL7168336.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVPVPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAASQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            30750..31961
                     /gene="dacA"
                     /locus_tag="LSX49_001918"
     CDS             30750..31961
                     /gene="dacA"
                     /locus_tag="LSX49_001918"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HBL7168337.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            32071..32334
                     /locus_tag="LSX49_001919"
     CDS             32071..32334
                     /locus_tag="LSX49_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HBL7168338.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            32435..33076
                     /gene="lipB"
                     /locus_tag="LSX49_001920"
     CDS             32435..33076
                     /gene="lipB"
                     /locus_tag="LSX49_001920"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HBL7168339.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDESTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA"
     gene            33336..33860
                     /locus_tag="LSX49_001921"
                     /pseudo
     CDS             33336..33860
                     /locus_tag="LSX49_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415162.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
     gene            34101..35066
                     /gene="lipA"
                     /locus_tag="LSX49_001922"
     CDS             34101..35066
                     /gene="lipA"
                     /locus_tag="LSX49_001922"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HBL7168340.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(35166..35369)
                     /gene="tatE"
                     /locus_tag="LSX49_001923"
     CDS             complement(35166..35369)
                     /gene="tatE"
                     /locus_tag="LSX49_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HBL7168341.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(35498..36286)
                     /locus_tag="LSX49_001924"
     CDS             complement(35498..36286)
                     /locus_tag="LSX49_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
                     /protein_id="HBL7168342.1"
                     /translation="MLVAAGQFAVTSVWEKNVEICASLMAQAAENEVSLFVLPEALLA
                     RDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG
                     NIVARYAKLHLYDAFAIQESRHVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
                     LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPF
                     GVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL"
     gene            36379..36762
                     /gene="crcB"
                     /locus_tag="LSX49_001925"
     CDS             36379..36762
                     /gene="crcB"
                     /locus_tag="LSX49_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HBL7168343.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIG
                     AFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(36816..37025)
                     /gene="cspE"
                     /locus_tag="LSX49_001926"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(36816..37025)
                     /gene="cspE"
                     /locus_tag="LSX49_001926"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HBL7168344.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(37200..37760)
                     /gene="pagP"
                     /locus_tag="LSX49_001927"
     CDS             complement(37200..37760)
                     /gene="pagP"
                     /locus_tag="LSX49_001927"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HBL7168345.1"
                     /translation="MNVSKYVAIFFFVFIQLISVGKVFANADEWMTTFRENIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGQSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     ATFQMTYIPGTYNNGNVYFAWMRFQF"
     gene            38347..39732
                     /gene="dcuC"
                     /locus_tag="LSX49_001928"
     CDS             38347..39732
                     /gene="dcuC"
                     /locus_tag="LSX49_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HBL7168346.1"
                     /translation="MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFIRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
     gene            complement(39773..40453)
                     /gene="dpiA"
                     /locus_tag="LSX49_001929"
                     /gene_synonym="citB"
     CDS             complement(39773..40453)
                     /gene="dpiA"
                     /locus_tag="LSX49_001929"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HBL7168347.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(40422..42080)
                     /gene="dpiB"
                     /locus_tag="LSX49_001930"
     CDS             complement(40422..42080)
                     /gene="dpiB"
                     /locus_tag="LSX49_001930"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HBL7168348.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSIISAVKTRDYKRLATIADKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKPGALEKGESYFITGKGSIGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMVIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELYLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
BASE COUNT        10513 a        10831 c        10424 g        10384 t
ORIGIN      
        1 tgtgtcgaat atgttcggca aattcaaaaa ccaatttgtt ggggtatcgc caagcggtaa
       61 ggcaccggat tctgattccg gcattccgag gttcgaatcc tcgtacccca gccaatttat
      121 tcaagacgct taccttgtaa gtgcacccag ttggggtatc gccaagcggt aaggcaccgg
      181 attctgattc cggcattccg aggttcgaat cctcgtaccc cagccacatt aaaaaagctc
      241 gcttcggcga gctttttgct tttctgcgta tattcaatgc cgaatacgat gttgactcgt
      301 cttatcctta caaagtcgga tgcgacgctg ccgcgtctta tccgacctac ggttggcatg
      361 catccagcaa tgttgtgagg ctacaaccct aacgcatatt tcagcgcctt acgtttcaac
      421 acgccagcac gctccgccgc catcaaacca agattacgca caaaacgcag cggtggcaga
      481 ttattgctga atccggcata aaacagatcc ataccacttt gcatcatgaa gttatccgcc
      541 atacgccgca tctggtaacg cttgagcaca ggataactgg cccacgcttc gccgtagctg
      601 cgggcgttca ccagaacgtc aatcagggca tcgacatcac gataaccaag attcactccc
      661 tgccccgcca gcggatggat ggtatgcgcg gcatcgccca ccagagcaag ccctggttgc
      721 acatactgca acgcatggcg acgtataagc ggaaacgcac cagcggcaag cggtgtcacg
      781 taacccagac gcgacgggaa atgcttcgcg atttccgcct gtagctgcgc catattcata
      841 ttctgcaact ggcgaatgcg cgccggagag tcataccaca ccagcgatgc ccagttatca
      901 aacaacggca gaaacgcacg cggtccgtcc ggggtaaatt gctgccaggt gctgtcgccg
      961 ggatcgttct cacactgtac gctaatcaac atacacgact gcgcatactg ccaggcatga
     1021 acgccaattc ccgccatctg tcgcacctgc gaatttgcgc cgtcggcacc aatcaccagc
     1081 ttcgcgagga tcgtttcacc gcccttcagt tccagctcct gaagatcatt atggcgatgc
     1141 agtgcagtca gcgaggttgg cacacgtaac gttactttcg gatgcgcttc cagcgcctgc
     1201 cacaaagcct gttgcaggac agtgttttcc accatgtagc caagcaacgg tagcttaagt
     1261 tcagcggcgt caaacacgac atgcgccgtt tcccactccc acgtttccag tctgcggtaa
     1321 ggatggcaac gcatagcctg tactgcatcc cagaccccta accctttaag caatgatacc
     1381 gaagccgcgc tgatcgccga gatccgcaca tccggttggc tgtcagcgac aaacggcgca
     1441 ggttctgcgt gctcgatcac cgttaccgta aacccgtgct gtgccagccc cagcgccagt
     1501 gcgccgccga ccattcctcc gccgacaatg gcaatttccg ttggttgatt tgtcatggtc
     1561 aatcatcctg ttagcaatat gctttaagtt tacaggattt ttacccccaa gggctgataa
     1621 cgctcatact ggtcacaacg gcagcaaagc attacactat gcgccctgca ttcctggcta
     1681 ctatttcgca agagcaagtc gatgaccaaa aaactccata ttaaaacctg gggctgtcag
     1741 atgaacgagt acgattcatc gaagatggcc gatctgctgg atgccaccca cggctatcaa
     1801 ctgaccgacg tggcggaaga agcggatgtg ctgctgctga acacctgctc aatccgcgag
     1861 aaggctcagg aaaaagtctt ccatcagttg ggtcgctgga aactgttaaa agagaagaat
     1921 ccagacctga ttatcggcgt cggcggctgc gtggcatcgc aagaaggcga gcacattcgc
     1981 cagcgcgccc actatgtcga tattattttt gggccgcaaa cgctgcatcg tctaccggag
     2041 atgatcaact ccgtgcgcgg cgaccgcagc ccggttgtag atatcagctt cccggaaatc
     2101 gagaagtttg accgtctgcc ggaaccgcgc gccgaagggc cgaccgcgtt tgtctccatc
     2161 atggaaggct gcaataaata ttgcacctac tgcgtggtgc cttacacccg tggtgaagag
     2221 gtaagccgtc cgtccgacga tattctgttt gagatcgccc agcttgcggc tcagggcgtg
     2281 cgtgaagtca acctgctcgg tcagaatgtg aatgcctggc gtggtgagaa ctacgacggc
     2341 accaccggaa cgtttgccga tctgctgcgt ctggttgcgg cgattgacgg gatcgatcgt
     2401 attcgcttta ccaccagcca tccgatcgaa ttcaccgacg atatcatcga agtgtatcgc
     2461 gacacgccgg agctggtgag cttcctgcac ttgccggtac agagcggttc cgatcgcatt
     2521 ctgaacctga tgggccgtac tcacacggcg ctggagtaca aagcgatcat ccgtaaactg
     2581 cgtgcggcgc gtccggatat tcagatcagt tctgacttca tcgttggctt ccctggcgaa
     2641 accaccgacg acttcgagaa aacgatgaag ctgattgccg acgtcaattt cgacatgagc
     2701 tacagcttta tcttctccgc tcgtccagga acgcctgccg ccgatatggt tgatgatgtt
     2761 ccggaagaag agaagaagca gcgtctgtat attctgcaag agcgcattaa tcagcaagcg
     2821 atggcatgga gccgccgtat gctcggcacc acccagcgta ttctggtaga aggtacatcg
     2881 cgtaagagca tcatggagct ttccggtcgt actgaaaata accgcgtggt taacttcgaa
     2941 ggcacgccgg atatgatcgg taaattcgtc gatgtagaaa ttaccgacgt ctatccaaac
     3001 tccctgcgcg gaaaagtggt gcgtactgaa gatgaaatgg gtctgcgcgt cgcagaaaca
     3061 ccggaatcgg tgattgcccg tacccgcaaa gaaaacgacc ttggcgtggg ttattatcag
     3121 ccgtaattct caggcccgcc gttccggtgg gccttgtttt ttctctcttt atccccatct
     3181 ttatcgcaat gcttgcgcct ttttcctgtg gcgtgaataa tttccttata ggccggtgaa
     3241 tgttcagctt ccggcggcat acagataaga ggaacggttt gaacatagac actcgcgaaa
     3301 tcaccctgga gccagcagac aatgcgcgtc tgttgagcct gtgcggcccg tttgatgaca
     3361 acatcaaaca actcgaacgc cgtctcggca tcgaaatcaa tcgccgtgat aaccacttta
     3421 aactgaccgg ccgtccgatt tgcgtcaccg ctgcggcaga cattctgcgt agcctgtatg
     3481 tcgatactgc cccgatgcgc ggtcagattc aggatatcga accggaacag atccaccttg
     3541 cgattaaaga agcgcgggta ctggagcaaa gcgcggagag cgtgccggag tacggcaaag
     3601 cagtcaatat caaaaccaaa cgcggcgtaa ttaagccgcg cacgccaaac caggcgcagt
     3661 acatcgccaa tattctcgac catgacatta ccttcggcgt tggcccggcg ggtacgggta
     3721 aaacctacct ggcagtggct gcggcagttg atgccctgga gcgtcaggaa attcgccgta
     3781 ttctgctgac tcgtccggcg gtcgaagccg gtgagaaact gggcttcctg cctggcgatt
     3841 taagccagaa agtagacccg tatctgcgcc cgctgtacga cgcgctgttt gaaatgctgg
     3901 gctttgagaa agtcgagaaa ctgattgagc gcaacgttat tgaagtcgca ccgctggcct
     3961 atatgcgtgg tcgtacgctg aacgacgcgt ttatcattct tgatgagagc cagaacacca
     4021 ccatcgaaca gatgaagatg ttcctgaccc gtatcggttt taactcaaaa gcggttatca
     4081 ccggcgacgt cacacagatc gacctgccgc gtaataccaa gtctggtttg cgtcatgcca
     4141 tcgaagtgct ggctgatgtc gaagagatca gctttaactt cttccacagc gaagacgtgg
     4201 ttcgtcaccc ggtggtggcg cgtatcgtta acgcttatga agcctgggaa gaagccgaac
     4261 aaaaacgtaa agcggcgctg gcggcagaac gcaagcgcga agaacaggaa caaaaatgag
     4321 tcaggtgatc ctcgatttac aactggcatg tgaagataat tccgggttac cggaagagag
     4381 ccagtttcag acatggctga atgcggtgat cccgcagttt caggaagaat cggaagtgac
     4441 tattcgcgtg gtcgataccg ccgaaagcca cagtctgaat ctgacctatc gcggtaagga
     4501 taagccgacc aacgtgctct ccttcccgtt tgaagtgccg cctggcatgg aaatgtcgct
     4561 actgggcgat ctggttatct gccgtcaggt ggttgagaag gaagctcagg agcaaggcaa
     4621 accactggag gcgcactggg cgcatatggt ggtgcacggc agtctgcatt tgttaggtta
     4681 cgatcacatc gaagatgacg aagcagaaga aatggaagcc atcgaaacag agattatgct
     4741 tgctctgggc tatgaggatc cgtacattgc cgagaaagaa taatttgcca ggcatttgac
     4801 tggcagacgt ccccgccgtt ggtgattaac gacggcgttt tgattaacta acatgagaac
     4861 ccatacgacg ccatgagcga cgacaattca cacagtagtg acacgataag caacaagaag
     4921 ggatttttct ccctgttact cagccaactt ttccacggtg aaccgaaaaa ccgtgacgaa
     4981 ctgctggcgc tgatccgtga ttccgggcag aacgacctta tcgacgaaga tacgcgcgat
     5041 atgctcgaag gggtgatgga catcgcagac caacgcgttc gcgacatcat gatcccccgc
     5101 tcccagatga ttaccctgaa acgcaaccag acgctggacg aatgccttga tgtcatcatc
     5161 gagtccgccc actcacgttt cccggtgatt agcgaagaca aagatcacat tgaagggatt
     5221 ctgatggcga aagacttgct gccgtttatg cgcagcgatg ctgaagcctt cagcatggac
     5281 aaagtgttac gtcaggcggt tgtcgttcct gaaagtaagc gcgtagaccg gatgctgaaa
     5341 gagtttcgct ctcagcgtta ccacatggcg atcgtcattg acgaattcgg tggggtttcc
     5401 ggtctcgtga ccattgaaga catcctggaa ctgattgttg gtgagattga agacgagtat
     5461 gacgaagaag atgatatcga cttccgtcag ctgagtcgtc atacctggac cgtgcgcgca
     5521 ctggcttcta ttgaagactt caacgaagcg ttcggcaccc actttagcga tgaagaggtt
     5581 gacactatcg gtggtctggt gatgcaggca tttgggcatc ttccggcgcg tggcgaaacc
     5641 atcgacatcg acggttacca gttcaaagtg gcgatggccg acagtcggcg tattattcag
     5701 gttcatgtca aaatcccgga tgactcaccc cagccgaagc tggatgaata aaaccgaaac
     5761 tggatagata actacatggc ttttgcctca ttaattgaac gccagcgcat tcgcctgctg
     5821 ctggcgttat tattcggtgc ctgcggaacg ctggccttct ctccttacga cgtctggcct
     5881 gcggcgatta tttcgctgat gggacttcag gcgctgacct ttaaccgccg tccactccag
     5941 tctaccgcta ttggcttttg ctggggattt ggcctctttg gcagcggtat taactgggtc
     6001 tatgtcagca tcgcgacctt tggcggaatg cctggcccgg ttaacatctt cctggtggta
     6061 ctgctggcgg cgtatttgtc gctgtatacc ggactgtttg ctggcgtgct gtcgcgtctg
     6121 tggccgaaaa ccacctggct gcgcgtggcg attgccgccc ctgctctctg gcaagtgacc
     6181 gagtttctgc gcggttgggt acttacaggc ttcccgtggt tacagttcgg ctatagccag
     6241 attgatggcc cgttaaaagg gctggcaccg ataatgggcg tggaagccat taacttcctg
     6301 ctgatgatgg ttagtggcct gctggcactg gcgttggtca aacgcaactg gcgtccgctg
     6361 gtggtggccg tcgtgctgtt tgcccttccc ttcccgctgc gttacgtcca gtggtttacc
     6421 ccgcaaccgg agaaaaccat tcaggtttcg atggttcagg gcaatattcc gcaatcgctg
     6481 aaatgggacg aaggccagct tcttaatacg ctgaagattt actacaacgc aacggcaccg
     6541 ctgatgggca aatcatcgct gattatctgg ccggagtcgg cgataaccga tctggaaatt
     6601 aatcagcaac cgttcctcaa agctctggac ggtgagttgc gcgataaagg tagctcgctg
     6661 atcaccggga ttgtcgacgc gcgtctcaat aaacagaacc gctacgatac ctacaacacc
     6721 atcatcacac tgggtaaagg cgcaccgtac agctatgaat cagccgatcg ctataacaaa
     6781 aaccatctgg tgccgtttgg cgagtttgtc ccactggagt cgattctgcg tccattagca
     6841 ccgttctttg atttgccgat gtcgtcattc agccgcggac catatattca gccaccgctg
     6901 tcgttgaatg gcattcaact tactgcggcc atttgctacg aaatcattct cggcgagcaa
     6961 gtgcgcgata acttccgccc ggataccgac tatctgctga ctatctccaa cgatgcgtgg
     7021 tttggtaagt ctattggtcc atggcagcac ttccagatgg cgcgaatgcg tgcgctggag
     7081 ctggcgcgcc cactgttgcg cagcaccaac aacggcatta cggcggtgat tggcccgcag
     7141 ggtgagattc aggcgatgat cccgcagttc acccgcgagg tgttaaccac taacgtaacg
     7201 ccgaccaccg gactcacccc gtactcacgt accggcaact ggccactgtg ggtgctgacg
     7261 gcactgtttg gctttgccgc tgtactgatg agtctgcgtg ctcgcaaacg ttaatgtgcc
     7321 tgatgcgcga cgcttatcag gcctacgcga tttttgcaat atgttgaatt ttcgcgattt
     7381 tgtaggataa agcgtacttt ttcaacacgc tctggggcat gattatcatg cccttttttc
     7441 ttacggttca gggatacaag ccacatcgcc atattgggga tgccgaataa ttgcctgcgg
     7501 atcaagtgaa ctttctctgt ccagttgtat tagcccgttc ttcgccataa caaatatctt
     7561 tctaccatcc gctgaaaaac gaagatgatt cacgtagctg gcaggataaa cgccaataat
     7621 ctgcccggca ttaatattga gcaggatgac ataaccttgc aggccatatg acaccaacgc
     7681 taaatattga ccgtccgggc taataccctc aacggaataa acgctcctgc tacaccattg
     7741 cgtcataatg ctggcttgtt gatcctcagc tcttatacgt gaaatcccct ggctatcggc
     7801 aaaaataatc tcaccatttt ttggtcggaa tcccatcgca gaaacgacac cacgcgcatc
     7861 acctgcggga aagtcttctt tctgatgcgt gatggtattg atccgcacga tgttacctct
     7921 gcctgctccc ggaaccagta atgttttttc atccggggaa agtgccataa cccaggcgcc
     7981 tggtttaccg ctcatccccg tcccgtcgta tttctccagc gggatatccg ccacatgctg
     8041 ataagccacc agatcaatcg ctgacacact attactggtg cgattcatca cccaggcttt
     8101 tgtgccatca cgcgagagga taaggctgtc aggatgtgcg ccggtggtaa tcgactgaat
     8161 aatctccccc gttgccacgt taatgaccga taatgcattc gcttcaaatg aagtcgcata
     8221 cagcaacgtt tcatccgggc ttagcgccag cgacctgacg ccctgatctt tacagccacc
     8281 acaatgtttg actgactttt ctttcgctat gggggctgta aaggtatgca ggattttctt
     8341 ttgtccgagg tcgaaaacaa caatgctgtt cgtgttttca attgcggcat acaacgtatt
     8401 agcatcccga ctgatcgcca tatcatggat atcggcaatc tcagcgagta aatcaccact
     8461 ggcctgctca cgacttaccg gagcggataa tgtttccctg agggcgttgc gctcctccac
     8521 taactgctgc tttttttgtc gtcgctcttg ttcaatctcc tgcggataaa acgcttcacg
     8581 caggctttgc ctgacctgta aaactgattc atcaatctgc tgctgcacaa gccagatagt
     8641 cccggtcaga agaagagtga ccgcaacaat aatcccgcct tccgtaacga gccgattttg
     8701 cccaactaaa cgcgcactca gccaacccaa cgcgcccccc gcaatcaggc cgccaatgtg
     8761 gcaagcgtta tctattcctg tttgccgggt accatacaac agtgtcagcg ccaccatacc
     8821 caacagagga aatactcgcc gctggttttt atggtgtgtg cccgcacctg aagcaagctg
     8881 tgttgctatc gcagcgcccg ctattcccat aattgccccg gatgccccaa cgctgatgac
     8941 tatctgctca ctttcgcgta acgcataaca ggcgctgatc agcccaccaa agatgccgga
     9001 gaataaccag ataatcagga gtcgccattt ccccagtatc cgttccgcca ctgtccccac
     9061 caccaggagt gcaaacatat tcatcagcaa atgggaaaaa ctactgtgca gaaaaacact
     9121 gctcaataag cgccaggatt catccgacaa cgtgagagaa gcaacgttag cgccgagatg
     9181 gatgagtgcg gattgatcga cttcttcgta actcatccat tgtgcgaggt aacaaaatat
     9241 cccaacacag agcgcaaaaa ggatcagggt tattgcgggt aattgaacat ttaacggctt
     9301 aaccgaagat gcagacataa ggtgattctt ccttgaaaag actagtaaaa agcattttcc
     9361 cgtgtgtagt tatcatcccg gcaaacgtcc cacaccgaaa agttaacact gtccgaaata
     9421 tgactttttc aaactgaaat tacaatcgta attaattcac ccctaagtat tttttggcat
     9481 gtaagttgct ttatttactg tgtaagcaat gaaatcagcc gcaacgcaac cgggttgcac
     9541 caccacaaat cagcggtagc accaaaaagg tgcggtttaa gaattttgct tcggaatggt
     9601 gcggcgcacc tcgcaaaaac aaacaataaa acagcaatat ctttacattt atccaaacta
     9661 aatgttacct aacaagcaca acactgcaca ataaagtcgc agatgataac aacacaaaca
     9721 ctcacaacgg gtatccatgc gtttttaacg cagaagataa aggagttgga tatgcaatta
     9781 cgtaaacctg ccacagcaat cctggccctg gcgctttccg caggactggc acaggcagat
     9841 gacgccgccc cggcagctgg caatacgctg gacaaaatcg ccaaaaacgg cgtgattgtc
     9901 gtcggtcacc gtgaatcttc agtacctttc tcttattacg acaatcagca aaaagtggtg
     9961 ggctactcgc aggattactc caacgccatt gttgaagcag tgaaaaagaa actcaacaaa
    10021 ccagacttac aggtgaaatt gattccgatc acctcacaaa accgtattcc actgctgcaa
    10081 aacggcactt tcgattttga atgcggttct accaccaaca atgccgaacg ccaaaaacag
    10141 gcggctttct ctaacactat tttcgtggtc ggtacgcgcc tgctgaccaa aaagggcggt
    10201 gatatcaaag attttgccga cctgaaaggc aaagccgtag tcgtcacttc cggcaccacc
    10261 tctgaagttt tgctcaacaa actgaatgaa gagcaaaaaa tgaatatgcg catcatcagc
    10321 gccaaagatc acggtgactc tttccgtacc ctggaaagcg gtcgtgccgt tgcctttatg
    10381 atggatgatg ctctgctggc cggtgaacgt gcgaaagcga agaaaccaga caactgggaa
    10441 atcgtcggca agccgcagtc tcaggaagcc tatggttgca tgttgcgtaa agacgatccg
    10501 cagttcaaaa agctgatgga tgataccatc gctcaggtgc agacctccgg tgaagcggaa
    10561 aaatggtttg ataagtggtt caaaaatcca attccgccga aaaacctgaa catgaatttc
    10621 gaactgtcag acgaaatgaa agcactgttc aaagaaccga atgacaaggc actgaactaa
    10681 ttacaagaac caggggcgga aattccagcc ctctcgattg ttacgtagca cggacagact
    10741 atacgcctgg tggtcgttcc ccatcgggcc tgaaaaccgc aatacgctgg gtaacaatct
    10801 tcgagggtag cagttaacgc tgctaccctc ttttttctgg agtagattta tgtctataga
    10861 ctggaactgg ggtatttttt tacaacaagc cccgttcggc aacaccacct atcttggttg
    10921 gatctggagt ggctttcagg tgacgatcgc tttgtcgatc tgcgcctgga ttatcgcttt
    10981 cctcgtcggt tcatttttcg gcattttacg taccgttcca aaccgttttc tctccggtct
    11041 gggtacgttg tatgtcgaac tgttccgcaa cgtgccgttg attgtgcaat tctttacctg
    11101 gtacctagtg atcccggagc tgctgccaga gaaaatcggc atgtggttta aggcagagct
    11161 ggatcccaat attcagtttt tcctttcatc catgctctgc ctggggctgt ttaccgccgc
    11221 ccgtgtttgc gaacaggtac gcgcagctat tcagtcgctg ccgcgtgggc aaaaaaatgc
    11281 cgcgctggcg atggatctga cgctaccgca ggcttaccgc tacgtactgc tgcctaatgc
    11341 ttatcgcgtt atcgtcccgc cgatgacctc agagatgatg aacctggtga aaaactccgc
    11401 catcgcctcg actatcggtc tggtggatat ggcggcgcag gcgggtaaat tgctcgatta
    11461 ctcggcccac gcctgggagt cgtttaccgc catcacgctg gcgtatgtat tgattaacgc
    11521 ttttatcatg ctggtgatga cgctggttga acgtaaagtt cgcctgcccg gcaacatggg
    11581 gggcaaataa tgtacgagtt tgactggagt tccattgttc cttccctgcc atatctgctc
    11641 gacgggctgg tgatcacgct gaaaatcacc gtcacggcag tggtgattgg tattttgtgg
    11701 ggcaccatgc tggcggtgat gcgcttgtcc agctttgcgc ccgtagcgtg gtttgccaaa
    11761 gcctacgtta acgtattccg ctcgattcct ttagttatgg ttttgctgtg gttttacctg
    11821 atcgtaccgg gttttctgca aaacgtgctg ggattatcac ccaaaaatga tatccgttta
    11881 atttcggcga tggtggcgtt ttcgatgttt gaagcggcct actattcaga gattatccgt
    11941 gctggtattc aaagtatttc tcgtggtcag tcgagcgccg cgctggcgtt gggaatgact
    12001 cactggcagt cgatgaaact gattattctg ccgcaggcgt tccgcgcgat ggtgccgctg
    12061 ttgctcactc agggcatcgt actgtttcag gatacctcac tggtgtatgt gttatctctg
    12121 gccgatttct tccgtaccgc ctcaaccatt ggtgagcgtg atggtacgca ggttgagatg
    12181 atcctgtttg ccggatttgt ttatttcgtt attagcctta gcgcgtcgtt gttggtcagc
    12241 tacttgaaaa gaaggacagc ataatgatta ccctgaaaaa tgtttcaaaa tggtatggtc
    12301 actttcaggt gctgaccgac tgctcaaccg aagtgaaaaa aggcgaagtt gtggtggttt
    12361 gcggcccgtc tggttccggc aaatcaacgc tgattaaaac cgtcaacggc ctcgaaccgg
    12421 tgcagcaagg tgaaatcacc gtcgatggca tcgtggttaa cgacaagaaa accgatctgg
    12481 cgaaactgcg ttcccgcgtc gggatggtgt ttcagcattt cgagctgttc ccccatctgt
    12541 cgattatcga aaacctgacc ctggcgcagg tgaaagtgct taaacgcaat aaagcgccgg
    12601 ctcgtgaaaa agcattgaaa ttgctggagc gcgtcgggct ttccgcacat gccaataagt
    12661 ttccggcgca gctttccggc ggccagcagc agcgtgtggc gatcgctcgc gcattgtgca
    12721 tggatcctat tgccatgctg ttcgacgaac caacgtcggc gctggatccg gagatgatca
    12781 acgaagtgct ggacgtgatg gtcgaactgg cgaacgaagg aatgacgatg atggtggtga
    12841 cccacgaaat gggctttgcc cgtaaagtgg cgaatcgggt gatctttatg gacgagggta
    12901 aaattatcga agactcgccg aaagacgctt tcttcgataa tccgaaatcg gaccgcgcaa
    12961 aagacttcct cgcaaaaatc ctgcattaat cactctggcg cgcatactca attgcgcgcc
    13021 atctcacgct ttctcgtttc gtccctcgta tctgttacat cccggcgtta cccttgtcgc
    13081 aaagaaacac acaacaagga gcaacaatgg cactgccaat tctgttagat tgcgacccag
    13141 gtcatgacga cgctatcgca atagttctcg ccctcgcctc accagagctt gatgtcaaag
    13201 caattacgtc ttccgccgga aaccagacac cagaaaaaac cttacgcaat gttctgcgta
    13261 tgctgacctt gcttaatcgc accgatattc cggtagcaag cggtgcggta aaaccgttaa
    13321 tgcgtaattt gattattgcg gacaacgtgc acggcgaaag cggcctggac ggcccggcat
    13381 tgccggaacc ggcatttgca ccgcaaaact gcacggcagt ggagctgatg gcgaaaacgc
    13441 tgcgtgaaag tgcggaacct gtcaccattg tttctaccgg accgcaaact aacgttgcct
    13501 tgctgctcaa tagccacccg gaactgcata gcaaaattgc ccgtatcgtg attatgggcg
    13561 gcgcaatggg gcttggtaac tggacgcctg cggctgaatt taatatttac gttgacccgg
    13621 aagcggcaga aattgtcttc cagtcaggaa ttccggtggt gatggccggt ctggatgtta
    13681 ctcacaaagc acaaatccac gttgaagaca ctgagcgttt ccgcgcgatt ggcaaccctg
    13741 tttcaaccat tgttgccgaa ctgctggatt tcttcctcga atatcacaaa gacgaaaaat
    13801 ggggctttgt cggcgcacca ctgcatgacc catgcaccat cgcctggctg ttgaaaccgg
    13861 agttgtttac cactgttgag cgctgggttg gcgtggaaac acaagggaaa tatacccagg
    13921 gtatgacagt tgttgattat tattatctga ctggcaataa accgaatgcc accgtaatgg
    13981 tcgatgttga tcgtcagggc tttgttgatt tactggctga tcgtctgaaa ttttacgctt
    14041 aacatacgtc attgattaag atcaccacgc attacctggg tggtcttaat ctggttatct
    14101 ctttttcttt caagatataa atgcaatgga taatgcagaa cttgctattg gtatcgatct
    14161 cggtactacc aatagtttaa ttgccgtctg gaaagacggt gccgcgcaat taattccaaa
    14221 taagttcggt gaatatttaa caccatccat aattagcatg gatgaaaata atcatatttt
    14281 agtcggaaaa ccggctgtat cacggcggac ttcgcatccg gataaaacgg cagcgttatt
    14341 taaacgtgca atgggcagta ataccaactg gcggttaggc agcgacacat ttaacgcgcc
    14401 agaactgtcc tctttggtat tacgctcatt aaaagaagat gccgaagaat ttctgcaacg
    14461 tccgattaaa gatgtggtga tctccgttcc tgcttatttc agcgatgaac aacgcaagca
    14521 tacccgttta gcagcagagt tagccgggct aaatgcagtg cgcctgatta atgagccaac
    14581 ggcagccgcg atggcgtatg gcctgcatac gcagcaaaat acccgctcgc tggtttttga
    14641 tctcggtggc ggcacgttcg acgttacggt gctcgagtac gccacgccgg tgattgaagt
    14701 taacgcctcc gctggcgata acttcctcgg tggcgaagat tttacccata tgctggtcga
    14761 tgaggtttta aaacgcgcgg aagttgccaa aaccacgctt aacgatagcg aactggcagc
    14821 cttgtacgcc tgcgtggaag cggcaaaatg tagcaatcaa tcgccaatgc acattcgctg
    14881 gcagtaccag gatgaaatgc ggaaatgcga attttacgag aacgaactgg aagatttgtg
    14941 gttgccgctg ctcaatcgct tgcgagtgcc gattgaacag gcgttgcgcg atgcacgtct
    15001 gaagccgagt caaatcgaca gtctggtgct ggttggcggc gcgtcacaaa tgccgctggt
    15061 gcagcgaatc gcagtgcgtc tgtttggcaa attaccgtat caaagttacg atccgagcac
    15121 cattgtcgcg ctgggcgcag caatccaggc cgcctgccgc ttacgcaatg aagatattga
    15181 agaagtgatc ctcactgata tttgccctta ctcgttgggt gttgaagtta accgtcaggg
    15241 cgtatccggc attttctcgc cgattattga acgaaacacc acagtaccgg tgtcgcgtgt
    15301 agaaacttat tcaaccatgc acccggaaca ggattcaatt acggttaacg tctatcaggg
    15361 agaaaaccac aaagttaaaa ataacattct tgtggaatcc ttcgatgtgc cgttgaagaa
    15421 aaccgggact tatcagtcga ttgatattcg ctttagttat gatatcaacg gcttgcttga
    15481 agttgacgtg cttctggaag acggcagcgt taagtccaga gtgattaatc acagtccggt
    15541 aacattgagc gcgcagcaga ttgaagagag tcggacgcgg ttatccgcat tgaaaattta
    15601 tccgcgcgat atgctcatca atcgcacctt taaagccaaa ctggaagagt tgtgggcgcg
    15661 ggcgctgggt gacgagcgag aagagattgg tcgggtgatc accgattttg atgcggcgtt
    15721 gcagtcaaac gatatggccc gcgtggatga agttcggcgg cgggcgagcg attatttagc
    15781 cattgagatc ccataaacac ggctaccgga tgcggcgtaa acgctgcatc cggcatcggc
    15841 gcaaaaaaca catcgtcaac taaacaacat cgcgattttg ccgagagcat aacctatcac
    15901 cagcaccgtt aaactgattt tgataatgct ggtaatgctc tgtggttttt catcctcatc
    15961 atttatttct tcatggtttt caggtgttgg ctcatcgaca tcttcatcct ccggctcgag
    16021 cttcactttc gtcaacagca ttcgggtgat aatggtctct aatggatgtg cctctccgcg
    16081 ttccagccgc gcgtccagac gggccagcat ctcttgtttc ggaaacgctt caagtactac
    16141 ctgttccgct acccgataca aatccagtaa cggtgaatct tgctctgtct cgctaccgac
    16201 tctcgatttc caccacgccc atgctttgcg tttgaagaat aacgactcaa taaacgattg
    16261 acctaacggc gataattttc cgctatgtaa aatctccgcc cataacagcc gcgtccgggc
    16321 gctctcacca ggaacatatt tcaacggctt accttgcgca tctaccatgc tccgcgcttc
    16381 gataaccatc actaataacg cgaaataatc cgggcaatga cgcttgctcc actgcaacaa
    16441 caaattatcg gcttgtgtag atgggtaact ttcccggtac gcgcagagat cggcaagcag
    16501 gctttccccc tcgccgcagt acaaccgttg tgcgcactgg taataacggg catcttcgct
    16561 ttctggttct tccgcttgcc actgttgagc gacaggaatg agttccgcca tacctgtttg
    16621 caccgagctg taccagcgca acagtttgcg atgcaacttc gcatcatcag gaatgaacca
    16681 cggaccttcc atcgccaaaa acgcagtgac atagtcagga tggtaacggc agcaacgttc
    16741 cagcgagaag taatactcaa ccgtctggtt ctgcaacgca acgggatatt ccagaaggct
    16801 aaggaaatcg aaacaatcac cagcctgaat ggcctcaaga aaagcctccc tttcttcctc
    16861 atctattcct tcgcagtcat taaacgaatg ccagttcaaa cgctctgcca gcaaagaagc
    16921 acaatttaat gaaagatatc gcgcttctat agcgattgca cacagcggcc agcgtaattg
    16981 atcgacatcc tccatgttcc aggtatttaa ttgctgaata aatttctgcc aggcggaggg
    17041 ctgaaaacga tcattttctg aatccagtaa tgccctgaat acacgtagta tttcatgctc
    17101 agtggcagca tctttttctt catcatctgc ttcctcgaca ggatttaccg ccagtcgcag
    17161 cgcctcttca taggcctggc gtaatgcttt aaacccttgt ggatcggttt cgggatgaca
    17221 taacggtaag cgagcaagat aagcctggcg gataatgtct atttgcgtcg tgctttcaat
    17281 ttcgaggatt tgccaacatg ttttcatagg tcgctcacat ccttaagcgt taccgggcat
    17341 tcaggctgga cagttaatgg ctgccaggga agcgtggcat agaaacggtc gcttcccgct
    17401 gccagctctt cgaacatccg actcccggcg ctatcgtatt tgtacagggt tagcgcctcg
    17461 cgtagcgaag cgttgtcttc gcactgagaa gattgccagt agagacgccc taacgaatag
    17521 gcagaaaaat agtgcatcca gctgtgatag taatggtgtg ctcgtatata gacgcgcgat
    17581 tgcagccata aactctcgtc ttccgtcaac cacttgttga gcacaccaac ccgtgataaa
    17641 aaacccatcc gcacataatc ccaggctttg attccccctt ccccacaaca catagcggtt
    17701 tgggcaacga attgggtata aatcaaccct ctctccgagc cgccagcaat taatgctttc
    17761 cactcttcag gggaagagcg atgccatgtc agatataagc cagctaaatc attggcatga
    17821 ccatcatcgg tcatctgata aatagtctga attaaatcat cacgattatt tattccccag
    17881 gatgatgaga gatcgaattc ttttatcccg gtatacattt ttggcgagtc atgcgcgggc
    17941 ttgcaaccct gattaagtat ttccatgggc gtagaaagcg caaaaagaag atattgttct
    18001 tccttattca tttgttaata atcccttaag tgcattaact gactactttt ttattattga
    18061 tgagtataaa cttgacgctt tcaaaataaa aagaaaatcg aagcattcac acatgaataa
    18121 aaaattaatg tatatattcg caatatttat agttgcagca ataacctgta ttagccaacc
    18181 caagaaaacg acgttgcgtg ataaagccat ggcgaattat gcctttgatt atttaagctc
    18241 accgggcagt cttccattca ccacggcagc cacggagctt tccgcgattc atggtcactc
    18301 aacgtcgcaa tatcgccttg gagaatttta tcttcatggt agcgacggta aaccactgga
    18361 ttatacacag gcgagatact ggtatgagca atcagcagaa caggaaaatc cacgcgcgca
    18421 aagtaaactg gggtggatct acctcaaagg tctgggggtc aaacccgaca cccgtaaagc
    18481 aattctctgg tataaggaag cagctgaaca agggtatgct catgctcaat atactttggg
    18541 tttgatctac agaaatggct caggtattaa tgttaaccat tatgaatctc aaaaatggtt
    18601 aaaactggcc gccaaacaac attacaaaaa tgcggaaaga ttacttgccg ggctttccgc
    18661 acattaacgt cgactgtcac ccgaacagat ggagtatttt ccctatcaaa ccagcaaaga
    18721 taaaaatata gaaaataatt ttaatgatgc ccagacagcc tggcccacca tcgtcaacgg
    18781 gcattggctg cggttgcggc tccgataacg ctggcgaagg ggtggaccag gactataagc
    18841 aagcgatgta ctggtatctg aaggctgctg ctcaggaaag cgtcggcgct tacgtcaaca
    18901 tcggttatat gtataaacac ggacaaggcg ttgagaaaga ttatcaggcc gcctttgaat
    18961 agtttacgat agccgctgaa tgcaatgacg ccacagcctg gtataacctg gccattatgt
    19021 atcactacgg agaaggaaga cctgtcgatc tccgacaggc tctcgacttg tatcgtaaag
    19081 ttcagtcatc cggaaccaga gatgtcagtc aagaaattcg tgagattgaa gatttactgt
    19141 agagataaaa acaagggccg gggaatttca ttcggcccat attctcttta ttgctgtgcg
    19201 aaatcagact attacggctc aaacgggcgt ctctggaact ggtcatgacc acatttaggg
    19261 catagcgtca gcacttccgg tgtgtagatc gggagatgga agtgacattt ctcgcagacc
    19321 agatttccca gccctaccac ttctccgctg tgataaaccc catgatgatt gaggtcctgg
    19381 aaaacttcgc gccattcaag ctgcgtttta tcggtgatgt ctgccagctc ctgccacaag
    19441 ctttctttaa tcacccgcat aaagacgctg tcagactctt ctttcaggct ctcttcatag
    19501 ctcatggcga actcttccag gtcacgtctg acagctcgcg tcagctcatc gacctcggtt
    19561 cgcgttaact cccctgtttt tattacgcgc tcgcgcgcct gttccaccag tgcgtcgata
    19621 tcacgttcgc cattgcgcag gcgttcgctc agtgacgcga ccagttcacg gtaatattga
    19681 gcaaccttgt tcatcgtttc atctcccggg tcgttaactg actataataa tagacgttct
    19741 ttgttccttg ctttgctaat acgcccacaa actctgtaaa ttaatgtatg aataatccgg
    19801 gcatcatttc aacgtcgagt gcgcgaaagg ctgttttgac gcgggcgttt gggctatgct
    19861 atgcggatct gaaaaaccac atcaacgcta catttgtagc cgtattgaaa acaggaccac
    19921 tggctgccat gcaagagcaa taccgcccgg aagagataga atccaaagta cagcttcact
    19981 gggatgagaa gcgcacattt gaagtaaccg aagacgagag caaagagaag tattactgcc
    20041 tgtctatgct tccctatcct tctggtcgac tacacatggg ccacgttcgc aactacacca
    20101 tcggtgacgt gatcgcccgc taccagcgca tgctgggcaa aaacgttctg cagccaatcg
    20161 gctgggacgc atttggtctg cctgcggaag gcgcggcggt gaaaaacaac accgcgccag
    20221 caccgtggac gtacgacaac atcgcgtata tgaaaaacca gctcaaaatg ctgggctttg
    20281 gttatgactg gagccgcgag ctggcgacct gtacgccgga atactaccgt tgggaacaga
    20341 aattcttcac cgagctgtat aaaaaaggcc tggtatataa gaagacttct gcggtcaact
    20401 ggtgcccgaa cgaccagacc gtactggcga acgaacaagt tatcgacggc tgctgctggc
    20461 gctgcgatac caaagttgag cgtaaagaga tcccgcagtg gtttatcaaa atcacagctt
    20521 acgctgacga gctgctcaac gatctggata aactggatca ctggccagac accgttaaaa
    20581 caatgcagcg taactggatc ggtcgttccg aaggcgtgga aatcaccttc aacgttaacg
    20641 actatgacaa cacgctgacc gtttacacta cccgcccgga cacctttatg ggttgtacct
    20701 acctggcggt ggctgcgggt catccgctgg cacagaaagc ggcggaaaat aatcctgaac
    20761 tggccgcctt tattgacgaa tgccgtaaca ccaaagttgc cgaagctgaa atggcgacga
    20821 tggagaaaaa aggcgtcgat actggcttta aagcggttca cccattaacg ggcgaagaaa
    20881 ttcccgtttg ggcagcaaac ttcgtattga tggaatacgg cacgggcgca gttatggcgg
    20941 ttccgggtca cgaccagcgc gactacgagt ttgcctctaa atacggcctg aacatcaaac
    21001 cggttatcct ggcagctgac ggctctgagc cagatctttc tcagcaagcc ctgactgaaa
    21061 aaggcgtgct gttcaactct ggcgagttta atggtcttga ccatgaagcg gccttcaacg
    21121 ccatcgccga taaactgact gcgatgggcg ttggcgagcg taaagtgaac taccgcctgc
    21181 gcgactgggg tgtttctcgt cagcgttact ggggcgcgcc gattccgatg gtgacgctgg
    21241 aagacggtac cgtaatgccg accccggacg accagctgcc ggtgatcctg ccggaagatg
    21301 tggtgatgga cggcattacc agcccgatta aagcagatcc ggagtgggca aaaactaccg
    21361 ttaacggtat gccagcactg cgtgaaaccg acactttcga cacctttatg gagtcctcct
    21421 ggtactatgc gcgctacact tgcccggagt acaaagaagg tatgctggat tccaaagcgg
    21481 ctaactattg gctgccggtg gatatttaca ttggtggtat cgaacacgcc attatgcacc
    21541 tgctctactt ccgcttcttc cacaaactga tgcgtgatgc aggcatggtg aactctgacg
    21601 aaccagcgaa acagttgctg tgtcagggta tggtgctggc agatgccttc tactatgttg
    21661 gtgaaaacgg cgaacgtaac tgggtttccc cggttgatgc tatcgttgaa cgtgacgaga
    21721 aaggccgtat cgtgaaagcg aaagatgcgg caggccatga actggtttat accggcatga
    21781 gcaaaatgtc caagtcgaag aacaacggta tcgacccgca ggtgatggtt gaacgttacg
    21841 gcgcggacac cgttcgtctg tttatgatgt ttgcttctcc ggctgatatg actctcgaat
    21901 ggcaggaatc cggcgtggaa ggggctaacc gcttcctgaa acgtgtctgg aaactggtgt
    21961 acgagcacac agcaaaaggt gatgttgcgg cactgaacgt cgatgcgctg actgaagatc
    22021 agaaagcgct gcgtcgcgat gtgcataaaa ctatcgctaa agtaaccgat gatatcggcc
    22081 gtcgtcagac cttcaacacc gcaattgcgg cgattatgga gctgatgaac aaactggcga
    22141 aagcaccgac cgatggcgag caggatcgcg ccctgatgca ggaagcgctg ctggcggtag
    22201 tccgtatgct taacccgttc accccgcaca tctgcttcac gctgtggcag gaactgaaag
    22261 gcgaaggcga tatcgacaac gcgccgtggc cggttgctga cgaaaaagcg atggtggaag
    22321 actccacgct ggtcgtggtg caggttaacg gtaaagtccg tgcaaaaatc accgttccgg
    22381 tggacgcaac ggaagaacag gttcgcgaac gtgctggcca ggaacatctg gtagcaaaat
    22441 atcttgatgg cgttactgta cgtaaagtga tttacgtacc aggtaaactc ctcaatctgg
    22501 tcgttggcta agcgcgggag gaagcgtgcg atatctggca acattgttgt tatctctggc
    22561 ggtgttaatc accgccgggt gtggctggca tctgcgtgac accacgcagg ttccttccac
    22621 tatgaaagtc atgatcctgg actcaggcga tccgaacggg ccattaagcc gtgcggtgcg
    22681 taaccagtta cgtctgaatg gtgtcgagtt gcttgataaa gaaaccacgc gtaaggacgt
    22741 tccatccctg cgtttgggta aagtgagcat cgcgaaagat accgcatcgg tattccgtaa
    22801 cggtcaaaca gcagagtatc agatgatcat gacggtgaat gcgaccgtgt tgatccccgg
    22861 ccgtgacatc tacccgatta gcgccaaggt cttccgttcg ttcttcgata acccgcaaat
    22921 ggcgttagcg aaagataacg aacaagacat gatcgtaaaa gagatgtacg accgtgctgc
    22981 cgaacagctg attcgtaagc tgccaagcat ccgtgctgca gatattcgtt ccgacgaaga
    23041 acagacgtcg accacaacgg atactccggc aacgcctgca cgcgtctcca ccacgctggg
    23101 taactgatga ttcggttgta cccggaacaa ctccgcgcgc agctcaatga agggctgcgc
    23161 gcggcgtatc ttttacttgg taacgatcct ctgttattgc aggaaagcca ggacgctgtt
    23221 cgtcaggtcg ctgcggcgca agggttcgaa gaacaccaca ctttttccat tgatcccaac
    23281 accgactgga atgcgatttt ttcgttatgc caggccatga gcctgtttgc cagtcgacaa
    23341 acgctattgc tgttgttacc cgaaaacgga ccgaatgcgg cgatcaatga acaacttctc
    23401 acactcaccg gacttctgca tgacgatcta ctgttgatcg tccgcggtaa taaattaagc
    23461 aaagcgcaag aaaatgccgc ctggtttact gctcttgcga atcgcagcgt gcaggtgacc
    23521 tgtcagacac cggagcaggc tcagctgccc cgctgggttg ctgcgcgcgc aaaacagctc
    23581 aacttagaac tggatgacgc tgcaaatcag gtgctctgct actgttatga aggtaacctg
    23641 ctggcgctgg cccaggcact ggagcgttta tcgctactct ggccggacgg caaactgaca
    23701 ttaccgcgcg ttgaacaggc ggtgaatgat gccgcgcatt tcaccccttt tcattgggtt
    23761 gatgctttgt tgatgggaaa aagtaagcgc gcgttgcata ttcttcagca actgcgtctg
    23821 gaaggcagcg aaccggttat tttgttgcgc acattacaac gtgaactgtt gttactggtt
    23881 aacctgaaac gccagtctgc ccatacgcca ctgcgtgcgt tgtttgataa gcatcgggta
    23941 tggcagaacc gccggggcat gatgagcgaa gcgttaaatc gcttaagcca gccgcagtta
    24001 cgtcaggccg tgcaactcct gacacgaacg gaactcaccc tcaaacaaga ttacggtcag
    24061 tcagtgtggg cagagctgga agggttatct cttctgttgt gccataaacc cctggcggac
    24121 gtatttatcg acggttgata tgaaatcttt acaggctctg tttggcggca cctttgatcc
    24181 ggtgcactat ggtcatctta aacccgtgga aacgctggcg aatttgattg gtctgacgcg
    24241 ggtcacaatc atccctaata atgttcctcc gcatcgtccc cagccggaag cgaacagcat
    24301 gcagcgtaaa cacatgcttg aactggcgat tgccgacaag ccattattta ctcttgatga
    24361 acgcgagcta aagcgcaatg ccccctctta cactgcgcaa acactgaaag agtggcggca
    24421 ggaacaagga ccggacgtgc cgctggcgtt tattattggt caggattcat tgctgacctt
    24481 tccgacctgg tacgaatacg aaacgatact cgacaatgca catttgatcg tctgtcggcg
    24541 tccaggttac ccacttgaaa tggcgcaacc gcaataccag caatggctgg aagatcattt
    24601 gacacataac ccggaagatc ttcaccttca gcctgccggt aaaatttatc tggctgaaac
    24661 gccgtggttt aacatctcgg cgaccatcat ccgcgaacgt ttgcaaaacg gtgaatcgtg
    24721 tgaggattta ttaccggaac cggtactgac ttacattaac caacaaggct tgtatcgctg
    24781 atacctgtcg ttacggaggg catgatgcga ctgtggttaa ttcgtcatgg tgaaacgcaa
    24841 gcgaatgtcg atggtctgta cagcggtcat gcgcccacac ccctgaccgc gcgcggtatt
    24901 gagcaagcgc aaaatctgca tacgctgcta catgatgttt cctttgacct ggttttatgc
    24961 agtgaactgg aacgggcaca gcataccgcg cgactggttc ttagtgaccg ccagcacccc
    25021 gttcatatca tccctgaact caatgaaatg ttttttggcg actgggagat gcgacatcat
    25081 cgtgacctca tgcaagaaga tgccgaaaac tatagcgcgt ggtgcaatga ctggcagcaa
    25141 gctatcccca cgaacggtga aggatttcag gcattttcgc aacgtgtgga acgatttatc
    25201 gcaaggctta gtgaatatca gcactatcag aatattttag tcgtcagcca tcagggcgta
    25261 ctgagtctgt taattgctcg tttaattggt atgcctgccg agtctatgtg gcatttccgc
    25321 gttgaccagg ggtgttggag cgccattgat atcaaccaaa aattcgcgac gctacgcgtc
    25381 ctcaatagcc gtgccatcgg ggtcgagaat gcatgacttt tctgtttttt tacgggtaag
    25441 ccgcaacgac cattgacagc cccgggcagg ctgatattct ccgcagccag actttttccg
    25501 ccagacacga ctttgtagaa attgttttac aaaaatggcg atgcaatctg cggcgcgggg
    25561 tgggatgata gcccactttc gaaagccgat tcggcgacaa ttgtcccgaa atcgcctctg
    25621 gttcaggtat actgacagac catttttatc tatttgattc acccaggggg aaaacttgca
    25681 gggtaaagca ctccaggatt ttgttatcga caaaattgat gacctcaaag gtcaggacat
    25741 catcgcctta gacgttcagg gcaaatccag catcaccgac tgcatgatca tctgtacggg
    25801 tacgtccagc cgccatgtta tgtccattgc tgatcacgtt gtgcaggagt ctcgcgcagc
    25861 gggcctgtta ccgctcggcg tagaaggtga aaacagcgcc gactggattg tcgtggattt
    25921 gggcgatgtg attgtccatg tcatgcagga agagagccgt cgcctgtatg aactggaaaa
    25981 actctggagt taatgcgtga agctgcaact tgtcgccgtg ggaacgaaaa tgccggactg
    26041 ggtacaaacc ggttttaccg agtacctgcg tcgttttccg aaagatatgc ccttcgagct
    26101 gattgaaatt ccggccggaa aacgcggcaa gaatgcggac atcaagcgca tactcgacaa
    26161 agagggtgag cagatgttgg cggccgcagg caaaaaccgc attgtcaccc tcgatattcc
    26221 aggcaagccc tgggatacgc cgcagttagc cgctgagctg gaacgctgga agctggatgg
    26281 tcgcgacgtc agtctactga ttggcgggcc tgaagggttg tcgcctgcct gtaaagcggc
    26341 ggcggagcag agctggtcgc tgtcggcact tacccttccc catccgctgg ttcgcgtgct
    26401 ggtcgcagag agtctgtacc gggcgtggag catcaccacc aaccatcctt atcaccgtga
    26461 gtgataagtg agctttgagt agaaaacgca gcggatgaaa ctacagaact cttttcgcga
    26521 ctatacggca gagtccgcgc tgtttgtgcg ccgggcgctg gtcgcctttt tggggatttt
    26581 gctgctgacc ggcgtgctta tcgccaacct gtataatctg caaattgttc gctttaccga
    26641 ctaccagacc cgctctaatg aaaaccgcat taagctggtg cctatcgcac ccagccgcgg
    26701 cattatctac gaccgtaacg gtatccctct ggctctcaac cgcactatct accagataga
    26761 aatgatgccg gagaaagtcg ataacgtgca gcaaacgctg gacgctttgc gcagcgtggt
    26821 tgatctgacc gatgatgata ttgctgcatt ccgaaaagag cgcgcacgtt cacaccgttt
    26881 cacctctatt ccggtgaaaa ctaacctgac cgaagtacaa gtagctcgct ttgccgtcaa
    26941 ccagtaccgt tttccgggtg ttgaagttaa aggctataaa cgtcgttact atccttacgg
    27001 ttcggcgttg acccacgtca tcggctatgt gtcgaaaatc aacgataaag acgtcgaacg
    27061 cctgaataat gacggcaaac tggccaacta tgcggcaacg catgatatcg gtaagctggg
    27121 cattgagcgt tactatgaag acgtgctgca cggtcagacc ggttatgaag aggttgaagt
    27181 taacaaccgt gggcgtgtta tccgccagtt aaaagaagta ccaccgcagg ccggacacga
    27241 tatttacctg acgctggatc tcaaactcca gcaatatatt gaaacgctgc tggcgggtag
    27301 ccgcgcagct gtggtagtca ccgatccgcg taccggtggg gtgttggcgc tggtttccac
    27361 gcctagttat gacccaaacc tgtttgttga cggtatctcc agcaaagatt attccgcctt
    27421 gctgaacgac ccgaatacac cgctggtgaa ccgcgccaca cagggggttt atcctcccgc
    27481 gtctacagtt aaaccctatg tggcggtttc ggcattgagc gccggagtga tcacgcgcaa
    27541 tacgacgttg tttgaccccg gctggtggca acttccaggt tcggaaaaac gttatcgtga
    27601 ctggaaaaaa tggggccacg ggcgtctgaa tgtcacaaga tcgctggaag aatctgcgga
    27661 taccttcttc tatcaggtgg cctacgatat ggggatcgat cgcctctccg aatggatggg
    27721 taaattcggt tatggtcatt acaccggtat cgacctggcg gaagaacgtt ccggcaacat
    27781 gcctacccgc gaatggaaac agaaacgctt taaaaaaccg tggtatcagg gtgacaccat
    27841 tccggttggt atcggtcagg gttactggac agcgacccca atccagatga gtaaggcact
    27901 gatgatcctg attaatgacg gtatcgtgaa ggttccgcat ttgctgatga gcaccgccga
    27961 agacggcaaa caggtgccat gggtacaacc gcatgaaccg cccgtcggcg atattcattc
    28021 cggttactgg gagctggcga aagacggtat gtacggtgtt gctaaccgcc ctaacggtac
    28081 ggcgcataaa tattttgcca gcgcaccgta caaaattgcg gcgaaatccg gtaccgctca
    28141 ggtcttcggt ctgaaagcga acgaaaccta taatgcgcac aaaattgccg agcgtttacg
    28201 tgaccacaaa ctgatgaccg cctttgcgcc atacaacaat ccgcaagtgg ctgtcgccat
    28261 gattctggag aacggtggcg cgggtccggc ggttggtacg ctgatgcgcc agatcctcga
    28321 ccacattatg ctgggtgata acaacaccga tctgcctgcg gaaaatccag cggttgccgc
    28381 agcggaggac cattaatcat gacggataat ccgaataaaa aaacattctg ggataaagtc
    28441 catctcgatc ccacaatgct gctgatctta ctggcattgc tggtttacag cgccctggtt
    28501 atctggagcg ccagcggtca ggatattggc atgatggagc gtaaaatcgg ccagattgcg
    28561 atgggtctgg tcatcatggt ggtgatggcg caaattcctc cacgcgttta tgaaggctgg
    28621 gccccctatc tctatatcat ctgtattatt ttgctggtgg cggtagatgc tttcggtgcc
    28681 atctctaaag gcgctcaacg ctggctggac ctcggtattg ttcgttttca accgtcggaa
    28741 attgccaaga tagccgtacc gttgatggtt gcacgcttta tcaaccgcga cgtttgccca
    28801 ccttcattga agaatacagc tatcgcgctg gtgctgatat ttatgcccac gctgctggtg
    28861 gctgcacagc ctgacctggg aacatcaatc ctcgttgcgc tttccggcct gtttgtactg
    28921 ttcctctctg gccttagctg gcgtctgatt ggcgtcgcag tagtgctggt agcggcgttc
    28981 attccgattc tgtggttctt cctgatgcat gattaccagc gccagcgcgt aatgatgctc
    29041 ctggacccgg aatcagaccc actcggcgca ggctatcaca ttattcagtc taaaattgct
    29101 attggctccg gcggattacg cggcaaaggc tggctgcacg gcactcagtc acagcttgaa
    29161 tttctccccg aacgccatac cgactttatc ttcgcggtac tggcggaaga gctgggatta
    29221 gtgggcattt tgattctgct cgctctctac attctgctga tcatgcgcgg gctgtggata
    29281 gccgccagag cgcaaaccac ctttggtcgc gtcatggctg gcggcttaat gctgatatta
    29341 ttcgtttatg tcttcgtaaa tattggtatg gtaagcggta ttctgccggt tgtaggggtt
    29401 ccgctcccac tggtcagtta tggaggatcg gcgctaattg tgctgatggc tgggttcggg
    29461 attgtaatgt caatccacac ccacaggaaa atgttgtcga aaagcgtgta agaggtgcgc
    29521 aatgcgtaag cagtggctcg ggatctgcat cgcggcagga atgctcgcgg catgtacaag
    29581 cgatgatggt cagcaacaga cggtaagtgt accgcagcct gcggtatgta acggccccat
    29641 agttgaaatt agcggggcag acccgcgttt cgaaccactg aacgcgacgg caaatcagga
    29701 ttaccagcgc gacggtaaaa gctacaaaat cgtgcaggat ccgtctcgat ttagccaggc
    29761 gggactggcg gcaatctatg atgccgaacc cggcagtaac ctgacggcct ctggcgaagc
    29821 tttcgatccg acacagttga cggcggccca tccaacgctt ccgatcccca gctacgccag
    29881 aatcactaac ctggctaacg ggcgaatgat cgtggtgcgc attaatgatc gcggccctta
    29941 tggcaacgac cgcgtgattt cgctttctcg cgcggcagct gaccgtctta acacgtcaaa
    30001 caacaccaaa gttcgtatcg atccgattat tgtcgcccag gatggttcgc tttctggtcc
    30061 tggtatggct tgtaccacag tcgccaaaca gacttacgcc ctgccagcac ctcccgattt
    30121 aagcggtggc gcgggaacaa gttcagtgcc tgtcccgcag ggtgacattc ttccggtcag
    30181 taattcgacg ctaaaaagcg aagatccgac cggcgcgccg gtaaccagca gcggtttcct
    30241 cggcgcacca acgaccttag cgcctggtgt actggaaggc agcgaaccga cgcctgcgcc
    30301 acagcccgtt gttacagctc cgtcgacaac gcctgcaacc tcacctgcaa tggtgacacc
    30361 gcaagccgcc tcgcaaagcg ccagcggcaa ctttatggtg caagtcgggg ccgttagcga
    30421 tcaggctcgt gcgcaacagt accaacagca actgggacag aagttcggcg tccccggtcg
    30481 cgtaactcaa aatggcgcgg tctggcggat ccagcttggc ccattcgcca gcaaagccga
    30541 agccagtacc ttgcagcaac gtttgcaaac cgaagcccaa ttacagtcat ttattaccac
    30601 cgcgcagtag cgtaaagcag gcatctgatg tgtcaatttc tgtaaatgac gttaacaaag
    30661 tcacgcggaa agtcagatgc ctgccggtag tgcatttgct atagtagggc acttttttta
    30721 attccatcac ggatgtcgta gttcagacca tgaataccat tttttccgct cgtatcatga
    30781 agcgcctggc gctcaccacg gctctttgca cagcctttat ctctgctgca catgccgatg
    30841 acctgaatat caaaaccatg atcccgggtg taccgcagat cgacgcggag tcctacatcc
    30901 tgattgacta taactccggc aaagtactcg ccgaacagaa cgctgatgtc cgccgcgatc
    30961 ctgccagcct gaccaaaatg atgaccagtt acgttatcgg ccaggcaatg aaagccggta
    31021 aatttaaaga aactgattta gtcactatcg gcaacgacgc atgggccacc ggtaacccgg
    31081 tgtttaaagg ttcttcgctg atgttcctca aaccgggcat gcaggttccg gtttctcagc
    31141 tgatccgcgg tattaacctg caatcgggta acgatgcttg tgtcgccatg gccgattttg
    31201 ccgctggtag ccaggacgct tttgttggct tgatgaacag ctacgttaac gccctgggcc
    31261 tgaaaaatac ccacttccag acggtacacg gtctggatgc tgatggtcag tacagctccg
    31321 cgcgagatat ggcgctgatc ggccaggcgt tgatccgtga cgtaccgaat gaatactcga
    31381 tctataaaga aaaagaattt acgtttaacg gtattcgcca gctgaaccgt aacggcctgt
    31441 tatgggataa cagcctgaat gtcgacggca tcaaaaccgg acacactgac aaagcaggtt
    31501 acaaccttgt tgcttctgcg actgaaggcc agatgcgctt gatctctgcg gtgatgggcg
    31561 gacgtacttt taaaggccgt gaagccgaaa gtaaaaaatt gctaacctgg ggcttccgtt
    31621 tcttcgaaac cgttaatcct ctgaaagtag gtaaagagtt cgcctctgaa ccggtttggt
    31681 ttggtgattc tgatcgcgct tcgttagggg ttgataaaga cgtgtacctg accattccgc
    31741 gtggtcgcat gaaagatctg aaagctagct atgtgctgaa cagcagtgaa ttgcatgcgc
    31801 cgctgcaaaa gaatcaggtc gtcggaacta tcaacttcca gcttgacggc aaaacgatcg
    31861 aacaacgccc gctggttgtg ctgcaagaaa tcccggaagg taacttcttc ggcaaaatca
    31921 ttgattacat taaattaatg ttccatcact ggtttggtta aaaattgaac acttgaaagt
    31981 gtaatttccg tccccatata ctaagcatca gtaaaaaact cccgccttct ggcgggagtt
    32041 gctatttaat tacgttacgc cggagctgac atgaaaacca aacttaacga actgcttgaa
    32101 ttccctactc cttttactta caaagttatg gggcaggcgt tacctgagct ggttgatcag
    32161 gtggttgaag tggtacagcg ccatgcgcca ggtgactaca ccccaacggt aaaaccaagc
    32221 agcaaaggca actaccactc ggtatctatc actatcaacg ccactcatat cgagcaggtt
    32281 gaaacactgt atgaagaact gggcaaaatc gatattgtcc gcatggttct gtaactcgct
    32341 tctccgttac ccggctcctg gtcgggtaac tcccctctcc tcgctgtgat atacttttcc
    32401 cccactttta ctcattctcc acggagatgc cgttttgtat caggataaaa ttcttgtccg
    32461 ccagctcggt cttcagcctt acgagccaat ctcccaggct atgcatgaat tcaccgatac
    32521 ccgcgatgaa agtacccttg atgaaatctg gctggtcgag cactatccgg tattcaccca
    32581 agggcaggca ggaaaggcgg agcacatttt aatgccgggt gatattccgg tgatccagag
    32641 cgatcgcggt gggcaggtga cttatcacgg gccggggcaa caggtgatgt atgtgttgct
    32701 taacctgaaa cgccgtaaac tcggtgtgcg tgaactggtg accttgcttg agcaaacagt
    32761 ggtgaatacc ctggctgaac tgggtataga agcgcatcct cgggctgacg cgcctggtgt
    32821 ctatgtcggg gaaaagaaaa tttgctcact gggtttacgt attcgacgcg gttgttcatt
    32881 ccacggtctg gcattaaacg tcaatatgga tctttcacca tttttacgta ttaatccttg
    32941 tgggtatgca ggaatggaaa tggctaaaat atcacaatgg aaacccgaag cgacgactaa
    33001 taatattgca ccacgtttac tggaaaatat tttagcgcta ctaaacaatc ctgacttcga
    33061 atatattacc gcttaattcc atacatcaat ggcccaattt acactgggtc attactcata
    33121 atacctgcta atgctttaca tctccttcgc gtttgtatat tttctttatc acttgcagaa
    33181 atgcgatgct acgccttgct ccgtagccca cctaattgat taactcattg aaataattga
    33241 ccatggtgag caaaagcgtt ccgtcccaat tagacataag attattgtaa tttttttaaa
    33301 tattattttt tcatgaataa aattggagta agtgcgtgga tagtaataat aaaattgaac
    33361 cctgtttaag cagaaaatcg tcagaaggta aaccacaaat atttacaacc ttacgaaata
    33421 ttgatcttac ccttctgact attttgaagt tgcatatgtc cataaaggaa tcgttaatgc
    33481 agcgaaagtg cttaatctgc cccccctcgg caatctatca gcctattcag aaactgcgcg
    33541 ttatattccc tgacctattg tttattcgca aaggccaggg tgtcactcct accgcatttg
    33601 cgatgtatct atatgagtct atcactcagg gacttgagtc cattcttggc gcgctggata
    33661 tcgaaggaag ctatgataag caacggacga taactattgc gccctccccc tcggtcggag
    33721 ccctggtcct tcctgtcatc tatcgggcga ttaaaactca ctatccacag cttttactgc
    33781 gcaacccgcc catcagcggc gcggaaaacc aactcagtca gtttcaaacc gatctcatca
    33841 tcaataacat gttttgcacg gggtcataga tgttatccgt aatgcatttt gaaaaagtat
    33901 tgttacagcc agatcacagc gcacaacgat aaaatggcac aatccaacaa caattttaca
    33961 ttttcgcgac cgctttggct gctttcaggt ccgtttcaat gatatactgc cagtcgttaa
    34021 ttcaaaaata gttgataatt acaacaatct attgaattga aacgctttcc ttcgtaattc
    34081 gcaactggaa cacgcacgct atgagtaaac ccattgtgat ggaacgcggt gttaaatacc
    34141 gcgatgccga taagatggcc cttatcccgg ttaaaaacgt ggcaacagag cgcgaagccc
    34201 tgctgcgcaa gccggaatgg atgaaaatca agcttccagc ggactctaca cgtatccagg
    34261 gcatcaaagc cgcaatgcgc aaaaatggcc tgcattctgt ctgcgaggaa gcctcctgcc
    34321 ctaacctggc ggaatgcttt aaccacggca ctgcaacgtt tatgatcctc ggcgctattt
    34381 gtacccgccg ttgcccgttc tgtgacgttg cccacggtcg cccggtagct cctgatgcca
    34441 atgaaccagt gaaactggcg cagaccattg ccgatatggc gctgcgttat gtggttatca
    34501 cctccgttga ccgtgatgat ctgcgcgatg gcggtgccca gcactttgcg gattgcatta
    34561 ctgccattcg ggaaaaaagc ccgcaaatca aaattgaaac tctggtgccg gatttccgcg
    34621 gtcgtatgga tcgtgctctg gatattctga ctgcaacgcc accagatgtg ttcaaccata
    34681 acctggaaaa cgtaccgcgt atttaccgtc aggtacggcc tggtgcagat tacaactggt
    34741 cgcttaagct gctggaacgc tttaaagaag cgcatccgga aatcccgacc aagtctggtc
    34801 tgatggtggg actgggtgaa accaatgaag aaattattga ggtaatgcgc gacctgcgcc
    34861 gtcatggtgt gacgatgcta acgctggggc aatatttgca gccaagccgc catcacctgc
    34921 cggttcaacg ttacgttagc ccggatgagt tcgacgaaat gaaagccgaa gcgctggcga
    34981 tgggctttac ccatgctgca tgcggtccgt ttgtccgctc ttcttaccac gccgatttgc
    35041 aggcgaaagg gatggaagtt aagtaatcct gtaataatta cttacatctg tctgataaaa
    35101 aacccgcttt ttgaagcggg tttttgtatc gaacaagata ttgagggagc gtcctgctcg
    35161 ccacgtcact ctttatgaga gagcttttca gcctgaagat caacgtctgc gccttttttc
    35221 gccgcagcat cgtcatcatt catcgccttc ttgaaccctt taatggccgc tccaaggtct
    35281 ccgcccagcg tacgtaactt cttagtccca aacagcagaa cgaccagcgc cgcaactacc
    35341 agcagtttgg taatactaat ctcacccata gataccttct tgacatataa ccggcaacag
    35401 aacgcgcctt aaaaaccaga gaatattaac ggtcattcga cgcgcgcaca caatagcaat
    35461 ctgtaacaag gtgaatcaag cgccgagtaa aaaaacatca taataattgc ggcggcgcaa
    35521 agcgacggtt gtttaagacg ggcagttgcg cgcgcacctg acgcacacgt tcgggcgtca
    35581 cttccgccat aatgagtgca ggcatttctg acgctgccgc aatggtgacg ccaaagggat
    35641 ctataatccg gctttgcccg atatttttgt tcccgcactc ccccgccgcc accatataac
    35701 aggtggtatc cagcgcacga gcggcaagca acgttgacca gtgatgctct ttgagcggcc
    35761 cacgaaccca ggcggcagga agtaccagta tttcagctcc ctgtaatgcc tgtgccagcg
    35821 ccagctctgg aaagcgtaag tcataacagg tcatcagacc gaccttcatc ccctccacct
    35881 ccagtaacgg agctatttca ttaccagcat caacatggcg tgattcctga atggcaaatg
    35941 catcatagag atgcagtttg gcataacggg cgacgatgtt tcctgcctgt agcgccacca
    36001 gcatattcca tgcgcgcccc ggtgttgaag gaacatgaat cgtcagaatt gtcgtcatca
    36061 tgttacgttt actttctcgc cgtaaacgac cgaggaattc gccttccagc agttgtgctg
    36121 atttaaccga tagatctgca tcatgatcat cacgcgccag taatgcttcc ggcaggacaa
    36181 acagcgaaac ctcgttttcc gccgcctgcg ccatcaacga ggcacaaatc tcaacgttct
    36241 tttcccacac agatgtaaca gcaaactgtc ctgcggcaac cagcattgcc acctcctgtc
    36301 agagtcgtaa aattcgccaa cggcgattat tcggcgttac acttatcact catacaaatc
    36361 aaatagcagg attttgcagt gttacaactt cttttagcag tttttattgg cggtggtacg
    36421 ggaagcgtgg cgagatggct gttaagtatg cgatttaacc cgctgcatca ggcgattccg
    36481 ttgggaacgc tggcagcaaa cctgattggg gcattcatca taggaatggg attcgcctgg
    36541 ttcagcagga tgacgaacat tgatccagtg tggaaagtat taatcaccac cggattttgt
    36601 ggcggtctaa caaccttctc aacattttcg gcagaagtgg tgtttttgtt acaagagggc
    36661 cgctttggct gggcgttact gaacgttttc gtcaaccttt tggggtcttt tgccatgacc
    36721 gcactggctt tctggctgtt ttccgcctca accgcacact aaagaccaaa aaaaacccgc
    36781 tgattaagcg ggttttgaat tcttgctgac gtatcttaca gagcgattac gtttgcagca
    36841 gaagggcctt tggcaccgtt agtgatttcg aactctacgc gctgaccttc agcaagagtt
    36901 ttaaaaccat tagtctggat tgcagagaag tgtacgaaca cgtctttgct gccgtcttcc
    36961 ggagtaatga aaccgaatcc tttggactca ttaaaccact taacgttacc tttaatctta
    37021 gacatcaaaa ttacctttac atgaaaaata gacacaaatg ctgtgtcggt taccagtaca
    37081 ccaattgtgg tacgctttgt ccagtgcaac tttactaaaa agtgataaaa gtcgcgttat
    37141 ttttgatgtt aattatttta gtggttgatt ttaaagaatt tactaaaact tcatttgtct
    37201 caaaactgaa agcgcatcca ggcaaagtac acattgccat tgttgtaggt acccggaatg
    37261 taggtcatct gaaacgtcgc ggggccatac cccacagagg ccaatggcag tagaaccgga
    37321 agagggatgt aattccagtt atcgcgcgcc gttacgccag cggtaaatcc caggcctaaa
    37381 tgaaaatttt catccgccag cggtcgccag gtactttccc atccgtatcc ggcaatcggt
    37441 tcccatttgt tccacgagtc cttaaatgcc attgcataca ggccatgcca gtttcctttt
    37501 tcatcccaac gcgactgacc aaaaccgcca ccccacggtc gctcgttata gcgatcggtt
    37561 ttttctttgt cataggcaaa acgcgcatgc caggtgatgg caggaatata taaatcataa
    37621 tgttctggct gttgccaggt ttgtgcaata ttttctctaa acgttgtcat ccactcatca
    37681 gcgttagcaa aaactttacc aacactgatt aactgaataa aaacaaagaa aaatatagcg
    37741 acatatttac tcacgttcat ttgtgaccat taaacattta tcaaaaatct actactaaca
    37801 tagcaaaact acaattaaca taacctcaat agccccaaca tgaagaataa tatgaatagc
    37861 tgctctattt atttccgcta gttcaagata aatatttccg cgcatcgatt aaagacgatg
    37921 catcgttttc tgcgatggga atagtcataa aagaaaaacc aagtcgtttc tgataacaaa
    37981 atacaaccga taaaaattac cttatttttt aataagatat aaaaaatatc ttaacgaaaa
    38041 atatattatg tatcgtcaac ccatgctcat ggaagattat tttttgagca cacaaccgca
    38101 gctaacacct tacaattaac aaatttgcat caatccgcca tcaatttaca cacattatta
    38161 tgtgatattt gccaaccgct aaatatgcgt tttgttatct acgtataaaa acagcaactt
    38221 caatgtctta atggcagttt ttcttgattt taatcagcat tcaccgccaa tttattgggc
    38281 atattttttc cttaactttt aggaattttt tattatttac tttggggcct ggagacagga
    38341 aaaattatgc tgacattcat tgaactcctt attggggttg tggttattgt gggtgtagct
    38401 cgctacatca ttaaagggta ttctgccact ggcgtgttat ttgtcggtgg cctgttattg
    38461 ctgattatca gtgccattat ggggcacaaa gtgttaccgt ccagccaggc ttcaacaggc
    38521 tacagcgcca cggatatcgt tgaatacgtt aaaatattgc taatgagccg cggcggcgac
    38581 ctcggcatga tgattatgat gctgtgtggc tttgccgctt acatgaccca tatcggcgcg
    38641 aatgatatgg tggtcaagct ggcgtcaaaa ccattgcagt atattaactc cccttacctt
    38701 ctgatgattg ccgcctattt tgttgcctgt ctgatgtcac tggccgtctc ttccgcaacc
    38761 ggtctgggtg ttttgctgat ggcaaccctg tttccggtga tggtaaacgt tggtatcagt
    38821 cgtggcgcag ctgctgccat ttgtgcctcc ccggcggcga ttattctcgc accgacttca
    38881 ggggatgtgg tgctggcagc gcaggcttcc gaaatgtcgc tgattgactt cgccttcaaa
    38941 acaacgctgc ctatctcaat tgctgcaatt atcggcatgg cgatcgccca cttcttctgg
    39001 caacgttatc tggataaaaa agagcacatc tctcatgaaa tgttagatgt cagtgaaatc
    39061 accaccactg cccctgcgtt ttatgccatt ttgccgttca cgccgatcat cggagtgctg
    39121 atttttgacg gcaaatgggg tccgcaatta cacatcatca ctattctggt gatttgtatg
    39181 ctaattgcct ccattctgga gttcatccgc agctttaata cccagaaagt tttctctggt
    39241 ctggaagtgg cttatcgcgg tatggcagat gcatttgcta acgtggtgat gctgctggtt
    39301 gccgctgggg tattcgctca ggggcttagc accatcggct ttattcaaag tctgatttct
    39361 atcgctacct cgtttggttc ggcgagtatc atcctgatgc tggtattggt gatcctgaca
    39421 atgctggcgg cagtcacgac cggttcaggc aatgcgccgt tttatgcgtt tgttgagatg
    39481 atcccgaaac tggcgcactc ctccggcatt aacccggcgt atttgactat cccgatgctg
    39541 caggcgtcaa acctgggtcg taccctatca cccgtttctg gcgtagtcgt tgcggttgcc
    39601 gggatggcga agatctcgcc gtttgaagtc gtaaaacgca cctcggtgcc ggtgcttgtt
    39661 ggtttggtga ttgttatcgt tgctacagag ctgatggtgc caggaacggc agcagcggtc
    39721 acaggcaagt aaatagtaat gccggaggca agtttcctcc ggctttatca tgtcacccac
    39781 tgtggtatat gcgttgcggt ctgccaactt tgccgtgaac aatttcagca ataatcagat
    39841 ggcggctggc gcaatattca agataacgcc tggcagtggt gcgactgatg gtcagtgcct
    39901 gcgccaccgt ttctgccgta tgttgcacac caggctcttt gaacagtttt cgcaccgcgt
    39961 ttagcgtcaa ggggtcaatg ccggtcggca gttcgtcttt gggttcaccg cgagcatagg
    40021 cattaaacat ctcatcaatt tgcttctggc tggcgctatc aatactttcc agcatatgtt
    40081 tacgctggcg gaaacgggtt agcgtttgcc ccagacgttc ataggcaatt ggcttaatga
    40141 gataatcaaa tacaccacaa cgtacggctt cagacaccgt ttccatatcg ctggctgcag
    40201 tggtaaacac cacgtcgccg ggataatgcg cctgcaccag ttcatgcagt aaattaatcc
    40261 ctctaccgtc aggaagatag ttatcgagca agattagccc cggcttaaaa cgctcgatca
    40321 tcattcgggc ctgcgccagg tttcccgcca gtaatatctg gctgaatccg ggaatgtgac
    40381 gaatatattc cgcatgcatc tctgccagcg gcgtttcgtc ctcaacgatc aatagggtta
    40441 atggagctgt cattaggttt cactttcgga atatagattg aaaataaggt accgcaggga
    40501 tcattatctt cgagagtgat aacaccaccg cagcgcgtta cgtagctggc aatcaagtac
    40561 aacccaatgc catgttcacc gggctcgtca gcacgcgtac tgacaccctg ctcaaatatt
    40621 ttgtctcgta gagactctgg aacgccgcag ccctgatcgg cgacttcaat caccacatca
    40681 tcgccttcat cgctgaggta taattcaaca atcttgtttc cttcatcgct acgcaggctt
    40741 gcttcgaagg cgttatcaag taaattgcca acaatggctg caaactcggt gctgtccagt
    40801 cctggcggca gttgcgaaag ctggctaccg gggacgatga ccatttttag ccccagttcg
    40861 cgggcgcgct gcactttacc aaaaagcagc cccgccacct ggcgatcggc aaacgcctca
    40921 cgcaggctgt caataagctg ttgctgggcc tgagactcac cctgcaccat cgccagcacg
    40981 cgatcatact ctttcatctg caacagacca ttgagcgtcg acatccaatt gagatgctcg
    41041 tgtcgcaatg tacgaaggct ctcgacgtat tgtttaattt gcgtcagttg cgcattgagg
    41101 gtggaaattt cgtctttact acgaaagctg ataatggccc ccagcaaatc atcgccagaa
    41161 cgaatagctt cccgattggc gataacgctc agaccgttaa agttcgccac cacatcctga
    41221 cgtttttcat caatctgttc ggtaaagaaa tcggcgggcc tgaccacttc agcaatgggt
    41281 ttacccaacc attgccgtcc gggggagctc agccccagca tctttcttgc gttacgattg
    41341 atggcggtaa tgtacccgtg cggatccacc gcaatcagcc cttcataaac cgaactaaac
    41401 agcgcctctt gctgacggac cacgcgtgcg atttgctttg gctccatgcc catcatctgc
    41461 cgacggatat gcgcggccag gaaccacgat agcaacatca aaatccctaa cagcacgaca
    41521 aacacgcctg ccatcggtaa taaaaactca gcccgccagc tatcgatttt actcaccaga
    41581 tagccaatcg acaccacacc gatgactttt ccatcgtcat caaagattgg cgttttggca
    41641 cgcatcgcca tgccaattga ccctttcccg gtgatgaagt agctctcccc tttctccagc
    41701 gcgcccggtt tggtgaactg cataggataa ccaattttct ccggattagg atggtaaaga
    41761 cgaatcgagt gccggtcgcc aatcaccaca taatcgaaat cagtatctct ttgtaatttg
    41821 tcagcgatgg tcgccagcct cttgtagtca cgcgttttca ctgcgctgat gatactgtca
    41881 ttagaagcaa taatttttgc ctgattcatt gccatgtcgc gcacatgaag cgttaaatag
    41941 tcctcaaaac tggccgtaaa atattgcgcc agggctgcaa tgacaaatat tgagaacacc
    42001 agaatcagca aaaagatacg cagcggaaat gccagtcttt ggaaaaatgc aaactgttta
    42061 ttctcgttaa gctgcaacat tgttttcctt gcgggttgtc ccgagcctct ttgacggatg
    42121 taattaaaat gttgaataaa aatacataga ta
//
LOCUS       DAFGPF010000032        41086 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFGPF010000032 DAFGPF010000000
VERSION     DAFGPF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41086
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.032"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(22..98)
                     /locus_tag="LSX49_001931"
     tRNA            complement(22..98)
                     /locus_tag="LSX49_001931"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(62..64),aa:Met,seq:cat)
     gene            307..1404
                     /gene="mltA"
                     /locus_tag="LSX49_001932"
     CDS             307..1404
                     /gene="mltA"
                     /locus_tag="LSX49_001932"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HBL7168349.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGVDNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            1481..2287
                     /gene="tcdA"
                     /locus_tag="LSX49_001933"
     CDS             1481..2287
                     /gene="tcdA"
                     /locus_tag="LSX49_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HBL7168350.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMNAGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(2338..2781)
                     /gene="csdE"
                     /locus_tag="LSX49_001934"
     CDS             complement(2338..2781)
                     /gene="csdE"
                     /locus_tag="LSX49_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HBL7168351.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLTQWEDKYRQLIMLGKQL
                     PALPEELKAQAKEIAGCENRVWLGYTVAENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TAAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAAAKQV"
     gene            complement(2781..3986)
                     /gene="csdA"
                     /locus_tag="LSX49_001935"
     CDS             complement(2781..3986)
                     /gene="csdA"
                     /locus_tag="LSX49_001935"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HBL7168352.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEASRQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNASDDKNIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKPELLEAMSPWLGGGKMVHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLTDYDINQAESWSRSLATLAEEALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            4178..4405
                     /locus_tag="LSX49_001936"
     CDS             4178..4405
                     /locus_tag="LSX49_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HBL7168353.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            4756..5673
                     /gene="gcvA"
                     /locus_tag="LSX49_001937"
     CDS             4756..5673
                     /gene="gcvA"
                     /locus_tag="LSX49_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HBL7168354.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGENPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            5692..6087
                     /locus_tag="LSX49_001938"
     CDS             5692..6087
                     /locus_tag="LSX49_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HBL7168355.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            6080..7180
                     /gene="rlmM"
                     /locus_tag="LSX49_001939"
     CDS             6080..7180
                     /gene="rlmM"
                     /locus_tag="LSX49_001939"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HBL7168356.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(7224..7955)
                     /gene="fucR"
                     /locus_tag="LSX49_001940"
     CDS             complement(7224..7955)
                     /gene="fucR"
                     /locus_tag="LSX49_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HBL7168357.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(8013..8435)
                     /gene="fucU"
                     /locus_tag="LSX49_001941"
     CDS             complement(8013..8435)
                     /gene="fucU"
                     /locus_tag="LSX49_001941"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HBL7168358.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            complement(8437..9855)
                     /gene="fucK"
                     /locus_tag="LSX49_001942"
     CDS             complement(8437..9855)
                     /gene="fucK"
                     /locus_tag="LSX49_001942"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HBL7168359.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTDCHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAVVMDNIERLISAQQLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATSIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDT
                     SLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTTQLQRNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            complement(9964..11739)
                     /gene="fucI"
                     /locus_tag="LSX49_001943"
     CDS             complement(9964..11739)
                     /gene="fucI"
                     /locus_tag="LSX49_001943"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HBL7168360.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVRKPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGKPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
     gene            complement(11772..13088)
                     /gene="fucP"
                     /locus_tag="LSX49_001944"
     CDS             complement(11772..13088)
                     /gene="fucP"
                     /locus_tag="LSX49_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HBL7168361.1"
                     /translation="MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYA
                     FGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAI
                     VLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALI
                     AMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN"
     gene            13635..14282
                     /gene="fucA"
                     /locus_tag="LSX49_001945"
     CDS             13635..14282
                     /gene="fucA"
                     /locus_tag="LSX49_001945"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HBL7168362.1"
                     /translation="MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTG
                     IPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
                     EANLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            14310..15458
                     /gene="fucO"
                     /locus_tag="LSX49_001946"
     CDS             14310..15458
                     /gene="fucO"
                     /locus_tag="LSX49_001946"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBL7168363.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLDVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTDEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(15563..16318)
                     /gene="xni"
                     /locus_tag="LSX49_001947"
     CDS             complement(15563..16318)
                     /gene="xni"
                     /locus_tag="LSX49_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HBL7168364.1"
                     /translation="MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTH
                     AVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNE
                     ADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
                     QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(16430..17797)
                     /gene="sdaB"
                     /locus_tag="LSX49_001948"
     CDS             complement(16430..17797)
                     /gene="sdaB"
                     /locus_tag="LSX49_001948"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HBL7168365.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     DSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            complement(17855..19144)
                     /gene="sdaC"
                     /locus_tag="LSX49_001949"
     CDS             complement(17855..19144)
                     /gene="sdaC"
                     /locus_tag="LSX49_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HBL7168366.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPIIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
     gene            complement(19701..21065)
                     /gene="ppnN"
                     /locus_tag="LSX49_001950"
                     /gene_synonym="ygdH"
     CDS             complement(19701..21065)
                     /gene="ppnN"
                     /locus_tag="LSX49_001950"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HBL7168367.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
     gene            complement(21177..22025)
                     /gene="queF"
                     /locus_tag="LSX49_001951"
     CDS             complement(21177..22025)
                     /gene="queF"
                     /locus_tag="LSX49_001951"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HBL7168368.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQLAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKVSVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATSGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPST
                     TRLVRQ"
     gene            22093..22638
                     /gene="syd"
                     /locus_tag="LSX49_001952"
     CDS             22093..22638
                     /gene="syd"
                     /locus_tag="LSX49_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HBL7168369.1"
                     /translation="MDDLTARALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            23260..23589
                     /locus_tag="LSX49_001953"
     CDS             23260..23589
                     /locus_tag="LSX49_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HBL7168370.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWRNDEPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNNQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
     gene            23589..24371
                     /gene="truC"
                     /locus_tag="LSX49_001954"
     CDS             23589..24371
                     /gene="truC"
                     /locus_tag="LSX49_001954"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HBL7168371.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLA
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            24389..24838
                     /locus_tag="LSX49_001955"
     CDS             24389..24838
                     /locus_tag="LSX49_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBL7168372.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDTLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDALLQEQSAQRVGEMLLIDASENPEPETESNPWVEHWGTMLS"
     gene            25272..26624
                     /gene="gudP"
                     /locus_tag="LSX49_001956"
     CDS             25272..26624
                     /gene="gudP"
                     /locus_tag="LSX49_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HBL7168373.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            26626..27966
                     /locus_tag="LSX49_001957"
     CDS             26626..27966
                     /locus_tag="LSX49_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HBL7168374.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGIGEAPGGEVIYQTLVGAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGQALNVPVCELLGPGKQRDAITVLGYLFYIGDRTKTD
                     LPYLENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            27987..29327
                     /gene="gudD"
                     /locus_tag="LSX49_001958"
     CDS             27987..29327
                     /gene="gudD"
                     /locus_tag="LSX49_001958"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HBL7168375.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKAT
                     PLPYQSQPDDQCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGTYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPLEIKGGLVQV
                     PEKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(29558..32314)
                     /gene="barA"
                     /locus_tag="LSX49_001959"
     CDS             complement(29558..32314)
                     /gene="barA"
                     /locus_tag="LSX49_001959"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HBL7168376.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSLPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFYHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            32371..33672
                     /gene="rlmD"
                     /locus_tag="LSX49_001960"
     CDS             32371..33672
                     /gene="rlmD"
                     /locus_tag="LSX49_001960"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL7168377.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGL
                     LPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILVPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LECFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVEPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQ
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            33720..35954
                     /locus_tag="LSX49_001961"
     CDS             33720..35954
                     /locus_tag="LSX49_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBL7168378.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            36050..36841
                     /gene="mazG"
                     /locus_tag="LSX49_001962"
     CDS             36050..36841
                     /gene="mazG"
                     /locus_tag="LSX49_001962"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBL7168379.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQIAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            37069..38706
                     /gene="pyrG"
                     /locus_tag="LSX49_001963"
     CDS             37069..38706
                     /gene="pyrG"
                     /locus_tag="LSX49_001963"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HBL7168380.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            38794..40092
                     /gene="eno"
                     /locus_tag="LSX49_001964"
     CDS             38794..40092
                     /gene="eno"
                     /locus_tag="LSX49_001964"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBL7168381.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(40152..41024)
                     /locus_tag="LSX49_001965"
     CDS             complement(40152..41024)
                     /locus_tag="LSX49_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HBL7168382.1"
                     /translation="MRYFILIFTLVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKEL
                     TRKLESIFNNTQVQIAVLIIPTTKDETIEQYAARVFDNWRLGDAKRNDGILIIVAWSD
                     RTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQQLAKGLELAIIALNNRLTSQHQY
                     SVNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDL
                     FLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKKASGRSYHSDNSGSGGGSSGGGFSG
                     GGGSSGGGGASGRW"
BASE COUNT        10161 a         9960 c        10911 g        10054 t
ORIGIN      
        1 tttacttcat caaattttaa ttggttgcgg gggccggatt tgaaccgacg accttcgggt
       61 tatgagcccg acgagctacc aggctgctcc accccgcgtc cgtggatgcg cactatactc
      121 tgctcgcgtt ttcatgcaac ctttttttta ccccgatcac ggatttggca tgattttgaa
      181 caaaaacaaa tcactagagc ctattttttg tgcaaaattt gcgtcaggga gaggctgctc
      241 atttcattaa acgcggtggt ttgttatctt cgttgcgcct tattttttaa cctgaagaag
      301 agaacaatga aaggacgttg ggtaaagtac cttcttatgg gcacggttgt ggcaatgctt
      361 gccgcctgct cttccaaacc aaccgatcgc ggacagcaat ataaagacgg gaaatttacc
      421 cagcctttct ctctggtgaa ccagccagat gccgttggcg cgccgattaa tgccggtgat
      481 tttgccgagc aaattaacca tatccgtaat tcgtcaccgc gtctgtatgg caaccagagt
      541 aatgtttata acgcggtgca agagtggctg cgcgcaggcg gtgatacccg caatatgcgc
      601 cagttcggca ttgatgcctg gcagatggaa ggtgtcgaca actatggtaa cgtgcagttt
      661 acaggctatt acacgccggt aattcaggcg cgccataccc gtcagggcga gttccagtat
      721 ccgatttacc gtatgccgcc aaaacgtggt cgtctgccgt ctcgtgcgga gatctacgca
      781 ggagcgctga gtgataaata tattctcgct tacagtaact ccctgatgga taacttcatt
      841 atggatgtgc agggtagcgg gtatatcgac tttggtgatg gcagtccgct taactttttc
      901 agctatgcag ggaaaaacgg tcatgcctat cgcagcattg gtaaggtgtt gatcgaccgt
      961 ggcgaagtga aaaaagaaga tatgtcgatg caggcgattc gtcactgggg cgaaacacac
     1021 agtgaagctg aggttcgcga gctgctggaa cagaacccgt ctttcgtctt ctttaaaccg
     1081 caatcttttg caccggtgaa aggggcaagt gcggtgccgc tggttggccg tgcttctgtt
     1141 gcctccgatc gttcaattat tccgccaggt actaccttgc tggcagaagt gccgctgctg
     1201 gataataacg gcaaatttaa cggtcagtac gaattgcgtc tgatggtggc gctggatgtc
     1261 ggtggcgcaa tcaaaggcca acacttcgat atctatcaag ggatcgggcc ggaagccgga
     1321 caccgcgcag gttggtacaa ccactatgga cgtgtctggg tgctgaaaac cgccccgggc
     1381 gcaggtaacg tctttagcgg ctgatgtgat attctgtatg ccgtttttac ggatatgaca
     1441 gggtgagggg taacctcacc ctttttaatt ctgaggtgct atgtctgtgg taattagtga
     1501 tgcatggcgt cagcgttttg gtggcacagc gcgtctgtat ggtgaaaaag cattgcaact
     1561 gtttgctgac gcgcatattt gtgtggttgg tatcggtggt gtcggttcct gggcggcgga
     1621 agcgctagcg cgcacgggga ttggtgcaat cacgcttatc gatatggatg atgtgtgcgt
     1681 caccaatacc aatcggcaaa ttcacgctct gcgcgataac gtcgggctgg caaaagcgga
     1741 agtcatggcg gagcgtattc gccagattaa cccggagtgc cgtgtaacgg tagtggatga
     1801 cttcgtgacg ccggataacg tagcgcaata tatgaatgcc ggttattcgt acgtgattga
     1861 tgctattgat agtgtacggc ccaaagcggc gctgattgct tattgtcggc gcaataaaat
     1921 cccgctggtc acgaccggtg gcgctggtgg gcagattgac ccgacgcaga ttcaggttac
     1981 cgatctggcg aaaacgattc aggacccgtt ggcggcgaag ttgcgcgagc gcctgaaaag
     2041 cgattttggc gtagtgaaaa acagtaaagg taagctcggc gtggattgcg tgttctctac
     2101 cgaagcgctg gtgtacccgc agtcagacgg caccgtctgt gcgatgaaag ccacggcgga
     2161 agggccaaag cggatggatt gtgcctcagg atttggcgcg gcgacgatgg tgaccgccac
     2221 ttttggcttt gttgcggttt ctcatgcgct gaagaagatg atggcgaaag cggcgcgtca
     2281 ggggtaaaca atcaggtcgg atgcgacgcg aacgtcttat ccgacctggt tctgtgctta
     2341 aacctgcttc gccgcagcga taatcgcctc gcttaacgca ttcaacccct ggctgcgtga
     2401 ggcgctaagt tgcgcacgta atcccagctc atcaaacaat gccagcggcg actgtgcctg
     2461 caattcggca gcggttttcc cctcaacggc agtcaacaac accgccaaca ggccgcgcac
     2521 aatgcgccct tcgctgtcgc caaagaaatg catcttgccg ttttcagcca cggtatatcc
     2581 cagccagacg cggttttcgc atccggcaat ctctttagcc tgcgctttta actcctctgg
     2641 caaagccgga agctgtttcc ccagcatgat caactgccga tatttatctt cccattgcgt
     2701 caacggtgcg aaggtattgc gtaacgtttc tgcggttacg gttgtgccga acggatgtcc
     2761 ggcgaattgc gggtttgtca ttaatccacc aataattcca gcgcgcggtc aacggcattc
     2821 accagcgcat ccacatcact ctttgtatta tatggcgcaa atgaggcgcg cagtgtgccg
     2881 gttacgccta attctgccag tagcggctga gcgcaatgct gcccggcgcg cagggcaata
     2941 ccgtactccg ccagcagtgt caccatatcg ctgtgatgaa ctccagcaaa atcaaaggcc
     3001 agcaggctgg aatcctggca gcggaatgaa cgaaagcctg gacgtttcgc cagcgcttct
     3061 tctgcaagcg ttgctaagct acggctccag ctttcggctt ggttgatatc gtaatctgtc
     3121 agccattcca gcgccgcgct taatcctatg acgccagcga catttggcgt tcctgcttcc
     3181 agtttccacg gcgcagattg agtcgtgaaa ccgtcaaaac tcacttcgtg aaccattttg
     3241 ccgccgccca gccagggcga catcgcttcc agcagttctg gtttgccata cagcacgccg
     3301 atgcctgtcg gaccatacag tttgtgacct gaaaaagcat agaaatcaat atccagttgc
     3361 tgaacatccg cggggaaatg caccgccccc tgagcaccat caaccatcac caccatcccg
     3421 gctgaatgag caaaagtaat cgctctcgcc agatccgggc aaccgccagt gacgttcgac
     3481 atctggccca acgccagaat ccgactacgg ggagtaatca gttctggcaa caaatcgaca
     3541 tccggcagtc gctgcgcatt aagcggcaat ttcaccactt tggcccccgt ttgttgggcg
     3601 accatcagcc aggggacgag gttggcgtgg tgttctgcca cactgacaat aatttcatcg
     3661 cccggttgca gacgcggacg ggcatagcat tgcgccacca tgttgatgga ttcagtggtg
     3721 ccgcgcgtcc agacgatatt tttgtcatcc gatgcattca gtaattgtgc cactttttcc
     3781 cgcgcagctt cgtaacgcgc ggtcaggcgt tgggcttcgg caaactggct gcgatggacg
     3841 tttccggcgc tcaggctata aaactgtcgg gaggcttcaa ccacggcttc aggtttaagc
     3901 gcggtcgcgg cgctgtcgag atagacgccc gcatcctgta gcgcgggaaa ctgggcgcga
     3961 aactgcgcgg gattaaaaac gttcatggta ctcctcggct tgatgcaccg atcgtgacgc
     4021 aaaattcact ttgatacaag gagagtgcta accatcagaa ttatctggat atcctggcga
     4081 agccgcgtca gtaacatatg ctgaatagtg ttaggcgtta attttagcct gttaatcaat
     4141 actattaaga tttattaatc gctttaagga gaagatgatg aaaaagactg ccgcaattat
     4201 ttctgcctgt atgctgactt ttgccctgag cgcctgttcc ggttcgaact atgtgatgca
     4261 caccaatgac ggacgtacca tcgtctctga cggcaaacca cagactgata acgataccgg
     4321 tatgatttcg tataaagacg ctaatggcaa caaacagcag atcaaccgta ccgacgtgaa
     4381 agagatggtc gaactggatc agtaattcgc gatcgcaagg taaaaaaaag caccgcaatt
     4441 aggcggtgct acattaatca ctatggacag acagggtaaa tgtacaggaa gtgaaaaaag
     4501 gtagctttgc taccatggtc tgaatcgcag accaattgca aacacaacaa cacaacatca
     4561 caaccgtaag ccaaaagttc accagaacac gcattccgat aaaacttttc gttccggctc
     4621 aggaagtgcc gccactatag gtatttgctg gtagaagctc aacggacaat ttataatggc
     4681 tcagattaaa aaaactaata ggttacacag tgtaatctaa ttgttaaatt catttaacat
     4741 caaagtttaa aagccatgtc taaacgatta ccaccgctaa atgccttacg agtttttgat
     4801 gccgcagcac gccatttaag tttcactcgc gcagcagaag agctttttgt gacccaggcc
     4861 gcagtaagtc atcaaatcaa gtctcttgag gattttctgg ggctaaaact gttccgccgc
     4921 cgtaatcgtt cactcctgct gaccgaggaa gggcaaagct atttcctcga tatcaaagag
     4981 atattttcgc aattaaccga agcgacgcgt aaactccagg cccgtagcgc taagggggcg
     5041 ttgacggtca gtttactccc cagtttcgcc attcattggt tggttccgcg actttccagc
     5101 tttaattcag cttatccggg aattgatgtt cgaatccagg cggttgatcg tcaggaagat
     5161 aagctggcgg atgatgttga tgtggcgata ttttatggtc ggggcaactg gccggggcta
     5221 cgggtggaaa aactgtacgc cgaatattta ttgccggtgt gctcgccgct actgctgact
     5281 ggcgaaaacc ccttgaagac cccggaagat ctggctaaac atacgttatt acatgatgcg
     5341 tcacgccgtg actggcagac atatacccga cagttggggt taaatcatat caacgttcag
     5401 caagggccaa tttttagcca tagcgccatg gtgctgcaag cggctatcca cgggcaggga
     5461 gtggcgctgg caaataacgt gatggcgcaa tctgaaattg aagccggacg tcttgtttgc
     5521 ccgtttaatg atgttctggt cagtaaaaac gctttttatc tggtttgtca tgacagccag
     5581 gcagaactgg gtaaaatagc cgcctttcgc caatggatcc tggcgaaagc cgctgctgaa
     5641 caagaaaaat tccgctttcg ttatgaacaa taatttacgt agggtacgac catgaccagc
     5701 cgttttatgc tgattttcgc cgccattagc ggcttcattt ttgtggctct gggcgctttt
     5761 ggcgcgcatg tgttaagtaa aaccatgggg gccgttgaga tgggctggat ccagaccggc
     5821 ctcgaatacc aggcgtttca tacgctggcg atcttaggtc tggcggtggc aatgcagcgt
     5881 cgcatcagta tctggtttta ctggagtagc gttttcctcg cgttaggcac ggtgctgttc
     5941 agcggcagcc tttattgcct ggcgctgtcc catctgcgtt tgtgggcgtt tgttacaccg
     6001 gttggcggcg tgagcttcct tgcgggttgg gcgttaatgt tagttggtgc tatccgttta
     6061 aagcgcaagg gcgtaagtca tgaataaggt tgtattgctg tgccgtccgg gctttgaaaa
     6121 agagtgcgcc gcagaaatta ccgataaagc cggccagcgg gaaattttcg gttttgcccg
     6181 cgtgaaagag aatgcgggtt atgtgattta tgaatgttat caacctgatg atggcgataa
     6241 gttaatccgt gagctgccgt tcagttcatt aatttttgcc cgccagtggt ttgtagtggg
     6301 ggaactcctg cagcatttgc cgccagaaga tcgtattacc cccattgttg gcatgttgca
     6361 gggtgtagta gagaagggcg gtgaactgcg tgttgaagtt gccgatacca acgaaagcaa
     6421 agagttgctg aaattctgcc gtaaattcac cgtgccgcta cgcgctgcct tgcgtgatgc
     6481 gggggtgctg gcgaactatg aaacgccgaa gcgtccggtt gtgcatgtat tctttattgc
     6541 accaggctgt tgctataccg gttactcata cagcaacaat aattcgccgt tctatatggg
     6601 cattccgcgc ctgaaatttc cggcagatgc gccgagtcgt tccacgctca aactggaaga
     6661 ggcatttcat gtgtttattc ccgcggatga gtgggatgaa cgcctggcga acgggatgtg
     6721 ggcggtggat ttgggcgctt gcccaggcgg ctggacctac caactggtga agcgcaacat
     6781 gtgggtttat tccgtcgaca acggcccgat ggcgcaaagt ctgatggata ccgggcaggt
     6841 gacgtggctg cgggaagacg gtttcaaatt ccgtccgaca cgcagcaata tctcctggat
     6901 ggtatgcgat atggttgaaa aaccggcgaa agttgcggca ttaatggcgc agtggctggt
     6961 taatggctgg tgccgtgaaa ctatcttcaa tctcaaactg ccgatgaaaa aacgctacga
     7021 agaagtgtca cacaatctgg cgtatattca ggcacagctt gatgaacatg gcataaatgc
     7081 tcagattcag gcgcggcagt tgtatcacga tcgcgaagaa gtgacggtgc acgtccgccg
     7141 tatctgggct gcggtgggtg gtcgtcgcga cgagcgataa caggcaaggc cggggcgtcg
     7201 tctccggcct gctacccttt ccgtcaggct gttaccaaag aagttgcaac ctggcgctca
     7261 tcagaaataa tgtgcgtgac ctcatccaga tgcccgatgc gggcttcccc tgaacgatta
     7321 aatttacttt tatcaatcaa taacaacgat tgcgcggcac gttttaataa cattgatttg
     7381 taatcagcgt tgatggcatt ggagtcccac agtgcgccgc tgctatcgat cccttcacaa
     7441 gaaaaaataa acagatcgat ttccagcgat ttaagttggg aaatcagcga gggattgacg
     7501 taacagccat atttgcgctc aagtgtgccg ccggaactga tcagttgaat gcgttcgcgt
     7561 ttaccgagtt catggcaaat cggatggcta ttggtgaaga cctggatgtt gatgtcaggc
     7621 aactggcgtg ccagatacca gcaggttgaa ctggcgtcta aggctatcac catcccttct
     7681 tcaatccacg cgagcgcctc gcgcgcgata tctgctttat gcgcataatg gcttttcagc
     7741 cggatgtgaa agggatcgcc actgtcttga ttttgacggt ggatatattt agcgcgccca
     7801 tgattgcgca gaattttacc ctgcgtctgt aattcattga gatcgcgacg aatggtttct
     7861 ttactgacct ttagctgttc agagagagct tccgtggtca ggctggtatg gttcagcagc
     7921 aggtcgacta tcgcttgctg gcgtgccgct ttcatatttt tcaccccatc attcgataac
     7981 cgcccgcgtc atgcgggcgt accggtatga gattacggtg ttaccccttt ttttaaaaga
     8041 atattcccgt acttcgctcg ttcgcctgtg ataacgatcg caaaggcttt ttgcgcccgt
     8101 tcataaaacg caaaacgatt gatgcggatg atgtcaggac acggggcttg tagtgaaagc
     8161 gcattacggt aacgtcgttc tacttcagga tcgagagtgt caccttctac cgccgccatc
     8221 atcaccagcg gtggtgcata actgtccagt tcaaataacg ggataatcgc ctggagcaag
     8281 tcgctcacca acaggccatc agcgcggatc acctgcggtc ccatcgaatg ggcgggaaag
     8341 tgagcatcgg aaaaaataat ttcatctcca tgccccatct ctgccagcac tttcaatagt
     8401 tcgggagaaa ttaacggcga aattgttttc agcatttcac acctcctcta taaattcagg
     8461 ttcagtttgc gggtagaaat aacggtactg ataatgaatc tgcgcgcggg cttcttccgg
     8521 gctgttaaat tcccctacgc cataccaacc aaacagcgca gctcctgcga cggtcgtttc
     8581 ggcatcgtcg agaactttta ccggaatatc aagcatattg gctttaatct gattccacaa
     8641 tgtgttgcga cttcctccgc cgactaacaa taattcagag gctttaaagt gcccgatttt
     8701 ttccagcatc tgtagattgc gctgtaattg cgtggttaac ccttccagcg ccgcgcgata
     8761 gaaatgcccc cgcgtggtat taagcgttac gccttgccag ccagcgttct ggcacgacaa
     8821 taaatcacac tgcattttca ctccatctgc gccaggcgcg atcaggcgag cttcttcaat
     8881 caacatttgc cagggagttt cagccgtcca gaacagtttt ctcacccatt ccagcacgcc
     8941 ggatgccagc cattgcatac ctgggttata caaccctgcc tggctatcca gttcgcaggt
     9001 agaaccggcg tactgactta acagcgaagt atcaacctgg gcgctgcgga ccattaaaat
     9061 ttcccatgta ccggaagaga gcacgggttc attttgttcg gcaccagcgc caaaaagggc
     9121 gaactgggta tcgtgacctg cggaaatcac cggtatgcca acgggtaagc cgagcattgc
     9181 tgcggcgctg ttctgtagcg taccaatctg ttcacccgct tccaccagac gagggaagag
     9241 tcggcgtgga atactggtgg cttgtaaaat ttgcggactg aaatcgcgtt gctggatatc
     9301 cagcatctgg ctggttccgg ccatcgtaat atcagtagtg aattcgccgg ttaaacggtg
     9361 gttaatcagc gacgaaataa agagccaggc gtgcgcgcgt tccagcagtt gtggatgatt
     9421 ttctttcaac cacaccaact tatataacgt attgaaacta aaggctccga ctccagaaat
     9481 agcctgcaac tgctgtgcgg agatcaaccg ttcaatattg tccattacca cggctgttcg
     9541 cggacatttc cagctaatga tcggatagag cagattgcct tgcttatcta ccagagcgcc
     9601 atccacacca aaggtggtga cggcgatacc acggatgtgg caatcagtca gttcactatt
     9661 gatttgccga cagcaatcag caaagcgttg caaaatggcg tctaaagacc actggtgcca
     9721 ggtgttgttt tccatcgcga tatcgctggc attaggcgtt gaggcgcggg caacaatttt
     9781 tccctgccga ttaaccgcga tggccctgac attggtcgcg ccacagtcga gtaccaggat
     9841 aacttcttgt ttcataatcg ctcctgcaat atagccggat aacattgctt atccggctaa
     9901 ccactcttgc ttgttcaggc ccggtagccg gagcgaccgg gcatcacatc agggagtcat
     9961 gtattaacgc ttgtacaacg ggccgtagtt ctggcaagcg cggtaatcct ggccttcaat
    10021 atccatgccg tgcgcggccc aggcagaagg acgatacact ttggtctctt caacgttgtg
    10081 catacatacc gggatacgca gcatggaggc aagagtgata aagtctgcgc caacgtggcc
    10141 gatggtcaga actccgtggt tagcgcccca gttcgccatt accgagtaca catccgtaaa
    10201 cggcccttta ccggtgaggc gcggtgcaaa ccaggtggtt ggccaggttg agttggtgcg
    10261 tttgttgagg atgtcatgca catccttcgg caattccacg ctccagcctt ccgcgatttg
    10321 cagtaccggt cccaggcctt tgatgatgtt gacacgagtc atggtgaacg ggacgccgcc
    10381 ttcggtaagg aagcgggaag agtaaccgcc gccacggaag tattcgtgga tcgccgggca
    10441 ccattcggta gcggcgaggc aagcgtcagc ctcttgctga gagatttccc agtgcggctt
    10501 catcgtcggt ttaccttcgc tgtcgcgttg tttacaggag ccgtccagcg cagcagaacc
    10561 ggagttgatc aaatggatga tgccgtgttc tgccagcccg tccagtttat gccccgttac
    10621 acgctcaatt gcttctggtg accagtaggt acggacatcg gcaaatacct gagcggtgcc
    10681 ggtgagctgg tggcccatta acattgccac gccgttaaga ctgtcgtttt cggtcgccac
    10741 gacaaacggt ttgcgcacgc cattccagtc aaatgaactg ttgaggatcg cttcagcggt
    10801 atcgccattg ggatattgat cggtccagtg acgttgcccc tggaagcctg cagcgatggc
    10861 gttgtagcca agtgattctt ccacgcgacc aatatcggcc agtttgctat tgccttgcat
    10921 catgtcgcgg atacacatcg ccatcagtaa actttcgcgc agaactgcgc ggctttgctc
    10981 ggcattgcgt tgatactgtt tgttattttc atcttcgcca tagcggaagt ttttatcagc
    11041 ccaggccagc gccatttcca gttcggcttc gtcgtaaatc ttctgatcga tacggcgacg
    11101 cagttcggtc atatccaccg cctggacttt cattcccagc caggattcaa agaagttgtg
    11161 atcaacgatg gaaccggcga tacccatcga aacgccgccc agcgacagat aacttttacc
    11221 tttcatgctg gcgactgcta aaccggcgcg ggcaaagcgc agcagttttt cttcaacatc
    11281 ggcaggaatc gatgtgtcat cggcatcctg aacgtcatga ccgtaaatgg agaatgccgg
    11341 gatgcctttc tggctgtgag ctgccagagc cgctgccagg taaacagcgc cgggacgttc
    11401 agtgccgtta aagccccaaa tggctttcgg gcgggttgga tccatgtcga tggtttcact
    11461 gccatagcac cagcaaggcg ttaccgtaat ggtgaggcct acattctgac tgctgaattt
    11521 ttcttcgcaa gcagcggctt cagccatacc cgcgatacag gtatcggaaa tgacacactc
    11581 gacggcagct ccgcaggcat ggcgcagttt ctcggtcagc agtgcagccg tggctttcgc
    11641 catattcatt gtttgttctt caagcgactc acgaacaccc atgcgacgac cgtcaataac
    11701 cgggcggata ccaattttcg gtaagctgat ttttttcatt actgattcct cactttattc
    11761 ggaaaatatg ttcagttagt tgccgtttga gaacggaaac gggcaaagat aaagatgact
    11821 gcgaagcaga gtgccgggat cagttcggca gtggggatgt tgcccgctgc gtcactgaca
    11881 aaccccatga ccggagtgac aataccgccg ccaataatgg tcataacgat gaaggacgaa
    11941 ccgtatttgg tgtcctggcc gagattctta atgcccagcg agaagattgt tgggtactga
    12001 atcgacataa aggcactgca taaagtcagg gctattaagc ccacatgacc gccagcgaag
    12061 gctgagatca ggcacagtgc catagcgatt aatgcgtagg ctgccaggac tttgtgtggc
    12121 gcgaagcgac tgatgagcca ggtaccggtg aaacgaccaa taaagaagca caccatggtt
    12181 ccggttaaat agttagcggc aaagcctgct gtcatacctg gaatttcttc tacagcgtag
    12241 cgaattaaat agctccagca ggccgtttgt gcgccaacgt agcagaattg cgctaatact
    12301 gcccagcgcc agtggcgaat acgcgccagg cgagaaagcg atgcggagaa cgatccttgt
    12361 ttggcgtcac tgtgattatc actctgcaat gccgggaatt tcgtcagcat gatcagcagg
    12421 gcgaccagta acacgatagc cacgatgatc atataaggtg tctgtaccga taataccaag
    12481 ctgtgtttat acgcactcaa ttgctctgga gacattttat cgagaacgtc ttgcgattga
    12541 tgtggcacgt tagacaaaat aagactttgc ccaaagacaa ccgcgataat tgcgccaaat
    12601 gagttaaatg tttgcgcaag atttaagcgg aagtgaccac tgctttccgg ccctaatacc
    12661 gtaacaaaag ggtttgcggc agtttccaga caacctaatc cggctgcaat aataaatagg
    12721 ccaactaaaa acaaggtgta gttcattatt tctgcggcgg gccagaataa tgcagcgccg
    12781 aaggcatata aaaacaatcc ggtaataatc cctgctttat aactgagttt tttcatcaat
    12841 atcccggcag ggattgggat aatgaaataa ccaaagtaaa aggccgattg gatcaggcca
    12901 gcctggaaat ttgtcagcgt aaaagcctgc tggaattgag gcaataaaat gtcgttaagg
    12961 ttattggcta ccgcccaaag aaaaaacagt gagcacagca gcgcgaatgg aataatgtaa
    13021 cttctgcttt gccctgcatc tttatctacc gcacggtaac tctgcgtttg tattgatgtg
    13081 tttcccatag catcctctta ggttcagaag cttaagcacg taatcggtta tgttttcaaa
    13141 agtgcaaaac cagcgagttc gggcttcata tcagtgaata tttgcctgtc tgaaatgaac
    13201 tcatggattc attttcaaat aaaaaacgct ctgtaatatg acggcggtca cacttattag
    13261 ccggagggtg actttatgtg actaccatca ctttaataat cgaaatttca tgcccgtttc
    13321 agaaaataaa tcataaaaaa cacaaaccag atgaccgtat taattgtttg tgccgaaaac
    13381 gggcattcct ggcagggagg agtagaaaaa tgaccgtttt gataaatatt tttaagagcg
    13441 gtcattttta atggggttat aaaaagagaa cttgcagtta tttactgtga ttagttgaac
    13501 caggtcacaa aatataagct tgtgaatttc tttctggtta atcaggaaga atatggtgag
    13561 taattaaacg gctaattcaa tagtgtgaaa ggaacaacat tattgccctg ttttgaatca
    13621 gagagaggta gctaatggaa cgaaataaac ttgctcgtca gattattgac acttgcctgg
    13681 aaatgactcg cctggggctg aaccagggaa cagcgggtaa cgtcagtgta cgttatcagg
    13741 atgggatgct gattacgcct acaggtattc catatgaaaa actgacggag tcgcatattg
    13801 tctttattga tggcaacggc aaacatgagg aaggaaaact cccctcaagc gagtggcgtt
    13861 tccatatggc ggcctatcaa agcagaccgg atgccaacgc ggttgttcac aatcatgccg
    13921 ttcattgtac ggcagtttcc attcttaacc gaccgatccc cgcgattcac tacatgattg
    13981 cggcggctgg cggtaattct attccttgcg cgccttatgc gacctttgga acacgcgaac
    14041 tttctgaaca tgttgcgctg gctctcaaaa atcgtaaggc aactttgtta caacatcatg
    14101 ggcttatcgc ttgtgaggcg aatctggaga aagcgttatg gctggcgcat gaagttgaag
    14161 tgctggcaca actttacctg acgaccctgg cgattacgga cccggtgcca gtgctgagcg
    14221 atgaagagat tgccgtagtg ctggagaaat tcaaaaccta cgggttacgg attgaagagt
    14281 aatttcgtaa agcaacaagg agaaggatga tggctaacag aatgattctg aacgaaacgg
    14341 catggtttgg tcgaggtgct gttggagctt taaccgatga agtgaaacgc cgtggttatc
    14401 agaaggcgct gatcgtcacc gataaaacgc tggtgcaatg cggcgtggtg gcgaaagtga
    14461 ccgacaagat ggatgccgca ggactggcat gggcgattta cgacggcgta gtacctaacc
    14521 caacaattac tgtcgtcaaa gaagggctcg atgtattcca gaatagcggc gcggattacc
    14581 tgatcgctat tggtggtggt tctccacagg atacgtgtaa agcgattggc attatcagca
    14641 acaacccgga gtttgccgat gtgcgtagcc tggaagggct ttccccgacc aataaaccca
    14701 gtgtaccgat tctggcaatc cccaccacag caggcactgc ggcagaagtg accattaact
    14761 acgtgatcac tgacgaagag aaacggcgca agtttgtttg cgttgatccg catgatatcc
    14821 cgcaggtggc gtttattgac gctgacatga tggatggtat gcctccagcg ctgaaagccg
    14881 cgacgggtgt cgatgcgctc actcatgcta ttgaggggta tattacccgt ggcgcgtggg
    14941 cgctaactga tgcgctgcac attaaagcga ttgaaatcat tgctggggcg ctgcgaggat
    15001 cggttgctgg tgataaggat gccggagaag aaatggcgct cgggcagtat gttgcgggta
    15061 tgggattctc gaatgttggg ttagggttgg tgcatggtat ggcgcatcca ctgggcgcgt
    15121 tttacaacac gccacacggt gttgcgaacg ccatcctgtt accgcatgtc atgcgctata
    15181 acgctgactt taccgatgag aagtaccgcg atatcgcgcg cgttatgggc gtgaaagtgg
    15241 aaggtatgag cctggaagag gcgcgtaatg ccgccgttga agcggtgttt gctctcaacc
    15301 gtgatgtcgg tattccgcca catttacgtg atgttggtgt acgcaaggaa gacattccgg
    15361 cactggcgca ggcggcactg gatgatgttt gtaccggtgg caacccgcgt gaagcaacgc
    15421 ttgaggatat tgtagagctt taccataccg cctggtaaat gtgctgatgt gataatgccg
    15481 gatgcgacgc tagccgcgtc ttatccggca tataagtgca ttaaattcaa tgtgttgata
    15541 atcgtttgca tccggcacgc cgttacctta ccaaccgcaa ttgctgtaaa ttgccgtcga
    15601 tatgcaaatc ggtttgtaag cgggcaatat cgcggcacag aaacgccatc tctttatggg
    15661 tttctaattt tttgcgccac ttttcggcaa ccgcatccag attctcatat atcccttcca
    15721 gactctgaaa ctcgaccagt agctgcgtgg cgctttttgg tccgatcccc gcaacacccg
    15781 gtacctttga actgctgatc cccgcaagcc cccagtaatc gggcaactgc tgcggttgaa
    15841 cgccaaattc tttatcgata aatggcgcat ccagccaacg tttctggaag taatcacgaa
    15901 tacgtaatgt cggtgaaagt aactgacagt agcctttatc tgtcgaaaca atcgttgcct
    15961 gatgcccggc ctgtgtcact ttgaccgcca gcgtggcggc taagtcatcg gcttcgttgc
    16021 cgctggcgga ccagcacggg acgccgcgtt gctcaaaggc ggcgcgtaat gcaggcatct
    16081 cgttgtgcaa ctcttccggc attggcggtc gacccgcttt gtaatctggt aaacgctgat
    16141 gacgccagcc gctactgcgg ttttcatcat caaaaacggc gaccgcgtgg gttggctggc
    16201 tgtgcataat gagctgatcg agcgcgtgct ggcaggtttc gacacagggc gaaccctgaa
    16261 cggcatgaat gcgacgaata agattcagtg catcgacaat aagcaaatga acagccacga
    16321 taaccccctt aaagatcagg cgataagggt aacattcgat gccagaacag gctatggctg
    16381 gatgagaaat cgggaagagg cctcgcaaaa agaggcctct ggagagcgat taatcgcagg
    16441 caacgatctt cattgccagg ccgccgcgag aggtttcgcg gtacttggcg ttcatatctt
    16501 tacctgtttc gtacatggtc tcgataactt tatcgaggca gacgcgcggc tcgctggtac
    16561 ggcgcagcgc catacgcgcg gcgttcaccg cttttactgc cgcaatggcg ttacgctcga
    16621 tgcacggtac ctgcacctgt ccagcaaccg ggtcacacgt cagaccgagg ttatgctcca
    16681 tggcgatttc cgccgcgatg cacacctgcg ccgggcttgc gcctaacagt tctgccagac
    16741 cagctgccgc catagagcac gccacgccga cttcaccctg gcagccgact tcggcaccag
    16801 aaatcgaggc gttcatctta taaagagaac caatggcgct ggctaccagc aggtaacgcg
    16861 ccagtgagtt agcgttcact tcgcggataa acttgtcgta gtacgccagc acggccggga
    16921 taatcccgca cgcaccgtta gtcggcgcag tcaccacgcg accgccagca gcgttctctt
    16981 cgttcactgc cagtgcaaac atgttgatcc agtcaactac cgccatcggg tcagtggtgg
    17041 ttttatcctg gctgaccagc atccggcgta gtgccgcagc acggcgtgga acgcgcagtt
    17101 tgccaggtaa cacgccttcg gtagaaatac cgcgttcaat accgccacgc atgacttccc
    17161 agacgttcgc caggtgctgt tccagctctt ctttgctgtg cagcgccagc tcgtttttca
    17221 tcatcaggcc agagagtgac agcccggttt cctgacaatg tttttgtaga tcggcagcgg
    17281 aactgtacgg ataaggaact tcaaccggtg cgctatcctg ctgaccaaaa tgctcttcat
    17341 caacgataaa gccaccgcca atagagtaat aagtctggct gtaaacgact ttatcgcccg
    17401 ccagcgcggt aatgcgcata ccgttttcat gcagagaaag gttgtcggca tggaagttca
    17461 tgcactgatc aaccgggaac tccacttcat gctgaccgtt tgccagcatc aggcgaccat
    17521 gagtattcac atcctgaata aaaccaggga tggaatcgat atccacggta tccggcaggt
    17581 tacccgccag acccataatt atggcgatat ctgtgtggtg gcctttaccg gtcagagaga
    17641 gcgagccgta cacgtcaacc accacgcggg tcacgtcttt aagcaggtta cgggcaatca
    17701 gatcgtcggt aaattgttta cccgctttca ttggtccaac ggtatgagaa ctggaagggc
    17761 caatgccgat tttgaaaata tcgaatacgc taatcatagg aaatacatcg cgttaaaacg
    17821 gaggaagcgc cgcccgaaag cggcgcgaaa ggacttagct gaacagagag tagaagattg
    17881 cggagattgc aatcagaccc atcacgacaa cgaatacgtt gctgatgtga ccgctgtact
    17941 tacgcattgc cggtactttc tgaattgcgt acatcggcat caggaacagg atcatcgcga
    18001 tgattgggcc gcccagggtt tcaatcatac ccaggatgct cgggttcagg gtggcaacaa
    18061 tccaggtcgt taccagcatg aacagcgcag tgatacggtt cagcttgttg atttcgatag
    18121 acttaccttt accacgcaga gatttaatca ccataccgtt gaagccttca cgtgcgccca
    18181 ggtagtggcc gaggaaggat ttggtgatag cgataatcgc gataatcgga gccatccacg
    18241 cgatgatcgg cgcgttaaag tggttagcca ggtaagacag aatcgagatg ttctgctctt
    18301 tagccgcagc caggtctgcc ggagtcaggc tcagtacgca gctgaagacg aagaacatta
    18361 cggtcagcac catcatgatg tgtgcgaatg ccaggatctt agagcatttc tgttctgcca
    18421 tatcgccgta ctcttcacgc ttcgcaacgg cgaaagaaga gatgatcgga gagtggttga
    18481 acgagaacac cattaccgga attgccagcc acagggtcat ccacagaccg tttccggttg
    18541 cagatgcagt gtccagagac agcgtttcca gtgctgcgcc gttccactgc gggatcaggt
    18601 acagagccag cagcatcagt acgccaacaa acgggaatac cagaatactc atcgctttaa
    18661 cgatcatctg ctcaccgaag cgaacgatgg tcatcatacc cacgatcagg atcagcgaca
    18721 gaatcgcacg tggcggtggc gtcataccca gttggtgaga catgaagctt tcaactgtat
    18781 tggtgattgc cacgctataa accagcagga tcgggtagat agcgaagaag tagagcagag
    18841 taatcagttt acctgcgcca ataccaaagt gttcttctac aacctcggtg atgtcttcgc
    18901 ccgggttttt accagacagt acgaagcgag tcaggccgcg gtgagcaaaa aacgtcatcg
    18961 ggaatgcaag gatagccatg atgatcagcg ggatcatacc gccaacaccg gcgttgattg
    19021 gcaggaacag cacgcccgcg ccgattgccg tgccgtaaag gcccagcatc cacatggtgt
    19081 ctgtcttgcg ccaggcacta cgagagtctt tcgacgcaat cgtgctggtt tgagtcgttt
    19141 ccatctattt ctcctggagg aatgcaaata attcagcttt tagccagttc agcccgggaa
    19201 ggtgcctgac cgtaaaaatg aaatctgtct atcggcgatg gcttaatcat tttccaccgt
    19261 aataatttga gggcggaaag atacacacaa gttatgtatc tatcagtgat cttgatccca
    19321 aatacaataa tctacttgga agatagataa tcacaacgct ttactctgta aatcaaaagt
    19381 aaaagagaat ttaagggcaa tatttgccca ttaaacgaca tctgacttct tctggggcgc
    19441 gcaatatatg taggttgaac tggaaaaatc aatactttta gttaatcatg gcgataattt
    19501 ctttttcatg gcgataaaat gtggtttatg aaaataggga aacgtttgcg tttcaacata
    19561 aattgtatga catattaact gtggtgatat ttgtcgcgtg aggttggtaa gaaacattca
    19621 tataacaaat gaaatgagtt gatgagtaag tgaccaaaaa cgataaaacc cggcaacaaa
    19681 cgtcaccggg ggaggggaga ttacgtgcag atttcgtagc aagggatgta ggctgagcct
    19741 ggcaacttca tacgatgctg ggcaacaaaa ccctgtagca ggtcgtccat acgacgcata
    19801 atctctttgt cgccgttgat tttgtaagga ccaaactctt caatggcgcg aataccgact
    19861 tcttttacat tacccgccac aataccggag aacgcacggc gcaggtcggc agccagcact
    19921 tcaacgggtt gatccgggta aagcttcaga ttagccatat tctcgtgaga cggctcaaac
    19981 ggcatttgca aatctggcgc aatgcgcatt gaccagttaa agctgtaagc gtcaccagtg
    20041 tcgcggcgat tttctttcac cagcggcatc gattttttca tctgacgagc gacttcagcg
    20101 gcgtcatcaa tgatgatgcg gtaatggcgg cgcgcgtttt cacccagcgt atgcacgaca
    20161 aactcgtcca gtacgcggaa gtagtcggcg ctctctttcg ggccggtgag gatcaatggt
    20221 aaaacctgat ctttgttggc cgggttcatt aaaattccca gcaaatacag caactcttct
    20281 gctgtaccca caccgccagg gaagataatg ataccgtgag cgatacggac aaacgcttcc
    20341 agacgttttt cgatatctgg catgatgatc aattcgttga ccagcgggtt aggcggttca
    20401 gcggcgataa tcgacggctc tgtcatacca ataaagcgac tgtctttgta acgctgctgc
    20461 gcgtgtccga ccgcagcacc tttcatcggc gcttccatcg ctcccggacc acagccggtg
    20521 cagatattca gttcacgcag gcccaactga ttcccgacgc gacgggcata caaatactcg
    20581 ttttcgttaa ttgagtgacc gccccagcag accaccatat ttggcgcttc accgacatgc
    20641 agcgcgcgag cgttacgcaa gatggaaaag accaggttag tgatgtggac ggagttgtcg
    20701 agattcaggt tgggaaaacg aacggtgtta tgaatttgcc cataaacgaa gagaatgtca
    20761 cgcagaaccg cgaacaagtt ggcctgcaaa gcgcgaataa ttcgcccatc gacaaaagcc
    20821 tcttccgggg gatttatcag ttccagcttt acgccgcgtt cacgtcgcag gacgttaata
    20881 tcgaaatttt caaaacgaga cagcaattct ttgctgttat cggtcaaact accggagttc
    20941 agtacggcaa gtgaacagtt gcgaaacagt tgatagaggt cgctgctggc ggtgcgttta
    21001 agcatatcca cttccagctg cgacaacata tccatggagc caagcgggct aatatgtgta
    21061 atcaagaaaa actccttatg ggacgaatat cgtcattccc tttgattaca atagccctgc
    21121 ctgatgacct ttcacaacct tctgcgtgaa tccagcacgc aaaattgaga aaaaatttat
    21181 tgccgaacca gtcttgtggt cgatgggaca aaatcgctat tactgcgcca cgggttaatg
    21241 tccagaccgc cacgacgggt ataacgtgcg taaacgctca atttctctgg ctggcagaag
    21301 cgtaacaggt cattaaagat gcgttccacg cactgttcgt ggaactcgtt gtgatgacgg
    21361 aaagagacca ggtaacgcag cagtttttct ctgtcaattt ggcgtccacg atactgaatt
    21421 tggatggaac cccaatctgg ttgatgggtg atcaggcagt ttgatttcag caggtggctg
    21481 acaagcgtct cttccactac tttttcaccg ctggtggcat tctccagata gtcagtagtg
    21541 aattcatagt tatcgatagt gatatcctgg tcatcaatgc aggtgccatt gaaatgacct
    21601 atcggctggc cttccagttc atcaagacga tataacgcca cgctaacctt accctgggcg
    21661 caagtgctta agtcgcgctc tagcgtctgg cgcacctcat cccagttatt aaaacgcgtc
    21721 tggttaaaac tgttgagata gagcttaaaa ctcttcgact caatcagatt tacgctggtg
    21781 taatcaagtt caacatgacc gacagcgagt tgcggcaaac ctttcgcatt cagccaggaa
    21841 agttcataca gcgtccagat atccgtaccg tgaaaaggca ggttatccgc tttcagaccc
    21901 agcgggtcgc gattcaggct gcgtggaacg ccttgcagta ggctggcgtc ataggtatcc
    21961 cggtaatcgg ttgattttcc aagtgtcagg cccgcaagtg cctgatggtt tgcataagaa
    22021 gacatgtttc accgtcataa accagataaa ctaaacgaca agtgtatctg gtttaagtga
    22081 agagagaaat tagtggacga tttgaccgca cgagccctga aagattttac tgcacgctac
    22141 tgcgatgcgt ggcatgaaga gcataaaagc tggccgttaa gtgaggaact gtacggcgtt
    22201 ccttcaccgt gcattatttc aactaccgaa gatgccgtat actggcaacc ccagccgttt
    22261 accggggaac aaaatgtaaa cgcggttgaa cgcgcttttg atattgtgat acaacccacg
    22321 attcatacct tttatacgac tcagtttgcc ggggatatgc acgcgcagtt tggcgatatc
    22381 aaactgacat tgctgcaaac ctggagtgaa gacgacttcc gtcgggtgca ggaaaatctg
    22441 attggtcatc tggtgactca gaaaaggcta aaactgccgc ccacgctatt tatcgcgacg
    22501 ctggaagaag agttagaggt catctcggtg tgtaatctct ccggtgaagt gtgcaaagag
    22561 acgctgggaa cacgtaaacg gacgcattta gcctcaaatc ttgcggaatt ccttaatcaa
    22621 cttaagcctc ttctgtaatc caaatacccc atctgattgt gagagatctc ttacagactc
    22681 tgtaggagat cgccaggaaa taagcgaata cttaaaaaga taagaatcgt tattctcatt
    22741 taaaaacaac atgttgcttg ttaattctta actttcatat gaaattttcc ttaaggcatt
    22801 gtctgtaagc gccttgtaag acttcgagaa aaagacgatt ctatcttcgt cgacagggag
    22861 tcagacaacg aagtgaacat caggatgatg acacttctga aggacacacc aggatggtgt
    22921 ttcagggaaa ggcttctgga tgaagcgaag aggatgacgc aggacgcgtt aaaggacacc
    22981 tccaggatgg agaatgagaa ccggtcagga tgattcggtg ggtcaggaag gccagggaca
    23041 cttcaggatg aagtatcaca tcggggtggt gtgagcagga agcaatagtt caggatgaac
    23101 gattggccgc aaggccagag gaaaagttgt caaggatgag cagggagcaa caaaagtagc
    23161 tggaatgctg cgaaacgaac cgggagcact gtgaatacag tgctcccttt ttttattcct
    23221 gctatccttc gcggcagttt ttcttattga ggttgcttta tgaccactca tgaccgcgtt
    23281 cgtctccagt tgcaggcgct tgaagcgtta ctgcgtgaac atcagcactg gcgaaacgat
    23341 gaaccccagc cgcatcaatt taatagtacc caaccgttct ttatggacac catggaacca
    23401 ctggagtggt tgcagtgggt gctgatcccg cgaatgcacg atttgttaga taacaaccag
    23461 ccgttaccgg gcgcttttgc tgttgcgccc tattatgaaa tggcgctggc gactgatcat
    23521 ccgcaacgcg cgcttattct ggctgagctg gagaaactgg atgctctttt tgcggatgat
    23581 gcgagctaat gctggaaata ctctatcagg atgaatggct ggttgcggta aataaaccct
    23641 ccggctggct ggttcaccgc agctggctgg atcgcgacga gaaagtagtg gtcatgcaaa
    23701 ccgtgcgtga ccagataggc cagcatgttt ttactgctca tcgtctggac cgaccaactt
    23761 ctggtgtgtt gttgatggga ttatccagcg aagccggacg gctgctggca caacagtttg
    23821 aacagcacca aatccagaaa cgttaccatg cgattgtgcg tggctggttg atggaagaag
    23881 cggtgctgga ttatccactg gtggaagaac tggacaaaat cgctgataaa tttgcccgcg
    23941 aagataaagg cccgcagcca gcagtgacgc attatcgcgg tctggcgacc gtagaaatgc
    24001 cggtagcgac tggacgttac ccgaccacgc gctacggcct ggtggaactg gagccgaaaa
    24061 ctggacgcaa gcaccagctt cgtcgccatc ttgcccattt gcggcacccg attattggcg
    24121 acagcaaaca tggtgattta cgccagaatc gcagcggtgc tgagcatttt ggccttcagc
    24181 ggttaatgct gcatgccagt cagttgtcat tgacgcatcc ttttactggc gagccgctgg
    24241 ctattcacgc gggcctggac gacacctgga tgcaggcgtt atcacaattt ggctggcggg
    24301 gtctgcttcc tgaaaatgaa agggttgagt tcagtgcgcc atcgggtcag gatggagaga
    24361 taagttccta atccagggag aaaacggtat ggcggaaatt ggtatttttg tcggcactat
    24421 gtacggaaat tcgctgttag tggccgaaga agcggaagcg attctgaccg cgcagggcca
    24481 caaagcaacg gtatttgaag atcctgaatt aagcgactgg ctgccctatc aggataagta
    24541 tgttctggtg gttacgtcca cgaccgggca gggcgacctt cctgatagca ttgtgccgct
    24601 ctttcaggga attaaagata ccctgggctt ccagccgaat ctgcgttatg gcgtgattgc
    24661 gctcggcgac agtagttatg tgaatttctg caatggcggc aaacagttcg atgccttgtt
    24721 gcaggaacag agcgctcagc gggttggcga aatgctgttg attgacgcca gtgagaaccc
    24781 ggaaccggaa acggaatcaa atccgtgggt tgaacattgg ggcacgatgt tgtcctgata
    24841 tgttcagcga gcggtaaatg ccgttttagc ggtgctgaat cgaatctttt caggcaaatg
    24901 ccagtaaaaa ctgcttcata gcgcggattt ttactggcgt ttgcctggag tcaagcgatc
    24961 catttcatac tcttctttat ttcttcgttt taacccttcc tttcttgttc ttgttttcat
    25021 ttccgtgaag tggattccac cgtccagggc taatgccaaa atcgggcctc attgaacgca
    25081 ttaatgttgt gttgttgcac ggtgagccgc tatggcgcgc tttttatact gctattgcca
    25141 gatataaaca cgcgccgtat tcggcgaacg acctataaaa acggcaaaaa caccctacgt
    25201 cacctctgat ttcctggcga tgtcgcagtc cagagtgagc gtggctaacg cgaattttca
    25261 ggagtgcaac aatgagttct ttaagtcagg ctgcgagcag tgtggaaaaa cgcacgaatg
    25321 ctcgttactg gatagtggtg atgttgttta tcgtcacatc cttcaactac ggcgaccgcg
    25381 ctacgctttc tattgccggt tcggaaatgg ccaaagatat cggccttgat cccgtgggaa
    25441 tgggctatgt gttctctgcc ttctcatggg cttatgttat cgggcagatc cctggtggct
    25501 ggttgctgga tcgttttggt tcaaaacgcg tctacttctg gtcgatcttt atctggtcga
    25561 tgtttacctt gctgcaaggc ttcgtcgata tctttagtgg attcggcatt atcgtggccc
    25621 tgtttacact gcgcttcctg gtcgggcttg ctgaagcgcc atctttccct ggcaacagcc
    25681 gcattgttgc ggcctggttt ccggcgcagg aaaggggaac ggcggtgtcg atttttaact
    25741 ccgcccaata cttcgcaacg gttatcttcg cgccgattat gggctggctg actcatgaag
    25801 tgggctggtc acacgtcttc ttctttatgg gcggtctggg cattgtcatc agctttatct
    25861 ggttgaaagt catccacgag ccaaatcaac atccgggcgt aaatcagaaa gagctggagt
    25921 acatcgccgc gggtggcgcg ctgatcaata tggatcagca aaacaccaaa gttaaagtgc
    25981 cgttcagcgt gaagtggggg cagatcaaac agctgctcgg gtcacggatg atgatcggcg
    26041 tttatatcgg tcagtactgt atcaacgccc tgacttactt tttcattacc tggttcccgg
    26101 tttatctggt gcaggcgcgc gggatgtcga ttctgaaagc gggctttgtg gcttccgttc
    26161 cggcggtttg cggttttatc ggcggtgtgt tgggggggat tatttccgac tggctgatgc
    26221 gtcgcacggg ttcactgaac attgcgcgta aaacaccgat cgtgatgggc atgttgttgt
    26281 cgatggtgat ggtgttctgc aactacgtca acgttgagtg gatgatcatc ggctttatgg
    26341 cgctggcctt cttcggtaag gggatcggtg cgctgggttg ggctgtaatg gctgatactg
    26401 cgccaaaaga gatcagcggt ctttccggtg gcctgttcaa catgtttggt aacatttctg
    26461 gcatcgtcac gccaatcgca attggttata tcgttggcac gactggctcc tttaatgggg
    26521 cgctgattta tgttggtgtt catgccttaa tcgcggtact cagctacctg gtgctggtgg
    26581 gcgatatcaa gcgtattgag ctgaaacctg tcgcggggca ataagatgac gacacaatcc
    26641 agtcctgtta ttactgatat gaaagtcatt ccggtcgccg gacatgacag catgttgctt
    26701 aatattggtg gtgcacataa cgcatatttc acccgcaata ttgtggtact caccgataat
    26761 gccgggcata ccggcattgg tgaagcgccg ggcggagagg tgatttatca aacactggtc
    26821 ggggctattc cgatggtgct gggccaggaa gttgcgcgcc tgaataaagt ggttcagcag
    26881 gtgcataaag gtaatcaggc agccgatttt gataccttcg gcaaaggtgc ctggactttt
    26941 gaattgcgcg ttaatgccgt agcggcgctg gaagccgcct tgcttgacct gttaggtcag
    27001 gcgctgaatg ttccggtctg cgaactgtta gggccaggca agcaacgtga tgctattacc
    27061 gttctcggtt atctgtttta tatcggtgat cggaccaaaa ccgatcttcc ttatctggaa
    27121 aatacgccgg gcaaccatga gtggtatcag ttgcggcatc agaaagcgat gaacagcgaa
    27181 gccgttgtgc gtctggcgga agcctcacag gatcgctatg gctttaaaga tttcaaactt
    27241 aagggtggcg tgttacctgg cgagcaagaa atcgacactg ttcgtgcatt gaagaaacgc
    27301 ttcccggatg cgcggattac cgttgatccc aatggtgcct ggctgcttga tgaagccatt
    27361 tctctgtgca aagggctgaa tgatgttctt acctatgcgg aagacccgtg cggcgctgag
    27421 cagggtttct ccggtcgtga agtgatggcg gagtttcgac gggcgaccgg cttgcccgtc
    27481 gcgaccaaca tgattgccac caactggcgc gaaatgggtc atgcggtgat gctcaatgcg
    27541 gtagatattc cacttgccga tccgcacttc tggacgcttt ccggtgcagt ccgcgtggcg
    27601 caactttgcg acgactgggg gctgacctgg ggctgccatt ctaataacca ctttgatatc
    27661 tctctggcga tgtttaccca tgtgggcgcg gcggcaccgg gtaatcctac cgctatcgat
    27721 acccactgga tttggcagga gggcgattgt cgtctgacca aaaatccgct ggagattaaa
    27781 aacggaaaaa ttgccgttcc tgatgcgccc ggtctgggcg tggaactgga ctgggaacag
    27841 gtacaaaagg cacatgaggc ctataaacgt ctgcctggcg gtgcgcgtaa cgacgcaggc
    27901 ccgatgcagt acctgatccc cggctggacc tttgaccgta aacgccccgt tttcggccgt
    27961 cattgattct gaaaaaggac ataaatatga gttctcaatt tacgacgcct gttgttactg
    28021 aaatgcaggt catcccggtg gcgggtcatg acagtatgct gatgaatctg agtggtgcac
    28081 atgcaccgtt cttcacgcgt aatattgtga ttatcaaaga taattccggt cacactggcg
    28141 taggggaaat tcccggcggc gagaaaatcc gtaaaacgct ggaagatgcg attccgctgg
    28201 tggtgggtaa aacgctgggt gaatacaaaa acgttctgac gctggtgcgt aatacgtttg
    28261 ccgatcgtga tgccggtggg cgcggtttgc agacatttga tttgcgtacc actattcatg
    28321 tagttaccgg gatagaagcg gcaatgctgg atctgttggg gcagcatctg ggggtaaacg
    28381 tggcatcgct gctgggcgat ggccaacagc gtagcgaagt cgaaatgctc ggttatctgt
    28441 tcttcgtcgg taatcgcaaa gccacaccgc tgccgtatca aagccagccg gatgatcaat
    28501 gtgactggta tcgcctgcgt cacgaagaag cgatgacgcc ggatgcggtg gtgcgcctgg
    28561 cggaagcggc atatgaaaaa tatggcttca acgatttcaa actgaagggc ggtgtactgg
    28621 ccggggaaga agaagcagaa tctattgtgg cactggcgca acgtttcccg caggcgcgta
    28681 ttacgctcga tcctaacggt gcctggtcgc tgaacgaagc gattaaaatc ggtacatacc
    28741 tgaaaggttc gctggcttat gcagaagatc cgtgtggtgc ggagcaaggt ttctccgggc
    28801 gtgaagtgat ggcagagttc cgtcgcgcaa ctggcctgcc gaccgcaacc aatatgatcg
    28861 ccaccgactg gcggcagatg ggccatacgc tctcgttgca atccgttgat atcccgcttg
    28921 cggatccgca tttctggacg atgcaaggtt cggtacgtgt ggcgcaaatg tgtcatgaat
    28981 ttggcctgac ctggggttca cactccaaca accacttcga tatttccctg gcgatgttta
    29041 cccatgttgc cgctgccgca ccgggtaaaa tcaccgcgat tgatacgcac tggatctggc
    29101 aggaaggtaa tcagcgcctg accaaagaac cgttagagat caaaggcggt ctggttcagg
    29161 tgccagaaaa accggggctg ggtgtagaaa tcgatatgga tcaagtgatg aaagcgcacg
    29221 agctgtatca gaaacacggg cttggcgcgc gtgacgatgc gatgggaatg cagtacctga
    29281 tccccggctg gacgttcgat aacaagcgtc cgtgcatggt gcgttaagac agaaaaccaa
    29341 aaccggctct atctggagcc ggtttgagac tgatgccaaa cgcaaaattg cctgttgcgc
    29401 tacgtatcag ggctacatca ttttttaatt cattgaattt aattggtttt gcaggccgga
    29461 taaggcgtta acgccgcatc cggcataaac acaggcactt gtcaccaatc tgaaaccagc
    29521 gtcataaaaa tccggttgct actcgacaag acgtccatta cccgagaatt ttgctggctt
    29581 cgcgcgctac attatccatc tcgtccaaca gttccagcag ctccggctcc aaatcttctt
    29641 ctttagtacc gctacgtagc tgttgttcga tcagttggca gagattcttc atacgcggta
    29701 caccgctata gccgcaactg ccatgcagtt tatgaatcaa atcaaccagg ccttccgggt
    29761 tttctccaac cagctgttcc tcaactttgt tgcgaacttc aggcaggaaa tcgagtaaca
    29821 tttgcagcat atcgcgcgct aaatcggttt ttcctgctgc ctggcgtagt gccagttgcc
    29881 agtcgagggt cgcattcggg ttgaccacaa tttcgttgac ttcgggcgtc acgacgcgag
    29941 aggaaatacc gctgccaggc ttgtagcgca acagcaaatt atgcaatcgc tcttcttcga
    30001 tcggtttggc gagataatca ctcatccccg cgccaagcag tttctctttt tgcccggcca
    30061 tcgcatgcgc cgttaccgcg ataaccggcg tttgctgctg atgcgggagc tggtggatga
    30121 gctcacatgc ccgaatgccg tccatgtccg gcatttgaat atccattaag attaaatcga
    30181 acggcatctg tttcgcccgt tcaactgcct gatgcccgct atcgcaaagt tccacatgtt
    30241 gcaccatatc ttccagcaat gcgccgataa gtttcaggtt agcggggttg tcatcaaccg
    30301 ccatgactgt cattgccagc ttactttcat cggttacagg caaaagcgtg ttttgtttgt
    30361 gatgataaaa ttccgtcagg gcaggcaaca ggcgcgtagg tgttaatggt ttcagcagac
    30421 acgcgccgat accatcttgc ttaagttttt cagcattgac ttgtgcatgg caaggaagtg
    30481 ccagcatcag gaaatcggtc atcgataccg ctttcgctaa tcgctcatgt tgcattgtta
    30541 gcggctcgcg gaaggtcacc gcgatgccta acaacatcat gtcgtaatgc gcgggaggca
    30601 gcgcggagaa cgttgggcta taaaccactt ccagcggcgt ttcacttaaa atatccagcg
    30661 tgcattgtgc tgctgcggag tttggttcga cataggccag gcgcttacca gcgaggcact
    30721 gggtggatgg cccttcgata ataatgttcg ggttcagatc gagattaatg tggaaccaga
    30781 aagttgaacc acgattcggc aggctatgga acgaaatatc accgcccatt tcattaacca
    30841 gtttttgtgt aatcaccagc cccagcccgg tgccaccatg acggcgggaa atactggcat
    30901 cagcctgtct gaaggcctgg aataagcgcg attgatcgcg ttcaggaata ccaatgccgg
    30961 tatcccgaat ctgcacttca atttgcactt tggtattact cagcgcacgt ttttccacca
    31021 gaatatcgat gttgccattc tcggtgaatt taatcgcgtt ccccaccagg ttagtgatga
    31081 tttgctgtaa acgtagcggg tcgccaatca cgttatcggg gacgtcgctc ttaatattga
    31141 gcgtcaattc cagcccttta tcgtgggaag agtgtgccag aagggtaacg acttcatcca
    31201 gcgtgctgcg cagtgggaac ggaatacttt ccagaatcag cttaccggct tccagtttcg
    31261 agaagtcgag aacatcatta ataattgcca gcaaattatt tgccgaacgt tcaatcgtat
    31321 tcaggtgatc gcgctgcgtt ggtgttaatt ctgttttcag cgtcaggcgg gtaaagccaa
    31381 taacaccatt cagtggtgta cgcagctcgt gtgacatatt tgccagaaac tcggatttaa
    31441 tacgcgccgc ttcctgggcg cgctttttcg ccagatccaa ctcaacgttc tgaatctcca
    31501 tttgctccag cgtctcacgc agatcggacg tcgcctggtc gatattgtgt tgcatctctt
    31561 cgtgataagc cgccagcgac attgccatcg agttgatacc gtttttcagc atatccagct
    31621 cgccgagcat aaatccttcc acccggctgt cgagttgccc gcgacggatg cggtcgacgg
    31681 tattcaccat gttgcgaatc ggaccggtta catcgcgcat taagcgccag ccaaaaataa
    31741 gcgcaatacc gatacaaaac agcatcatca cgctggaaat aaagatctct ttatattgct
    31801 gcaagcgaac cgatttaaga tccagctcaa gcgcaatata tcccaacata ttttgactat
    31861 ttttggcatc gctactgggc gattcgtcgg gggagtaact ctcagaaata atcggcgtgc
    31921 ggaggatcat aatatcgccg tcacgagtga cagtgagctg gcgaggaaac ggcacgttgc
    31981 tgccgagctg cattgatgag ggatcaagat gaaaattgga ggtgacaaag agtcggttat
    32041 tttcatcata aaccgaaatc gcgcgaacaa tatcagaatg gcgacgatgc agtacgctta
    32101 ttaactgacc gatagattcg cgattttgca gactcatgcc atattcagta gaaactgcaa
    32161 gcggctcaat aatgctggca ccggcatctt ccagttgacg ctgcaagtcg ttatagcgat
    32221 gcacgacgaa aaagatactc agcaataaac caataaggac ggtcggtgcc aggatcagaa
    32281 tcatcatgcg tgcgcgcagg ctgtagttgg tcatggagtt ccgttatggg acaattaagg
    32341 tcacactgtt aaattgagaa agtctcgcca atggcgcaat tctactctgc aaaacgacgc
    32401 acgacgacgc gtcagatcat aaccgtttca gtcaacgacc tcgactcttt tggtcagggt
    32461 gtggcgcgac ataacggcaa aacattattt atccccggat tattgccgca ggaaaacgcg
    32521 gaagttactg ttactgaaga taaaaaacag tatgcccgcg ctaaagtcgt acgccggtta
    32581 agcgatagcc cggaacgcga aacgccacgc tgtcctcatt ttggcgtatg cggcggctgt
    32641 cagcaacaac acgccagcgt ggatttacag cagcgaagca aaagtgcggc actcgcccga
    32701 ttaatgaaac acgaagtctc tgaagtgatc gccgatgttc cttggggcta tcgccgtcgc
    32761 gcgcgtttaa gtctgaacta cttaccgaaa acacagcaac ttcagatggg gtttcgcaaa
    32821 gcgggctcca gtgacattgt cgacgttaaa caatgcccca ttttagtgcc ccaactagaa
    32881 gcattgctgc ccaaagtcag ggcatgcctg ggcagcttac aagctatgcg ccatcttggt
    32941 catgttgaac tggtacaggc aaccagcggc acgctaatga ttttgcgcca taccgcaccg
    33001 ctaagttcgg cagatcgcga aaaactggaa tgcttttcgc attctgaagg cctggatctg
    33061 tatctcgccc ccgatagtga gatactcgaa accgtctctg gtgagatgcc ctggtatgac
    33121 tcaaatgggt tgcgcttaac ttttagcccg cgcgatttta ttcaggtcaa tgcgggtgtg
    33181 aaccaaaaaa tggtagcgcg tgcgttggaa tggctggatg tggaacctga agatcgcgta
    33241 ctggatctgt tctgcggtat gggcaacttt acactgccat tggcgacaca agctgccagt
    33301 gtggtcggtg tagaaggtgt tccggcgctg gtggaaaaag gccagcagaa tgcgcgtctt
    33361 aatggcttac agaatgtgac gttttatcac gaaaatcttg aagaagatgt cacaaagcag
    33421 ccgtgggcga aaaacggctt cgataaagtg ttgttggacc cggcgcgagc aggtgccgca
    33481 ggtgttatgc agcaaattat aaaactggaa cctattcgta tagtttatgt atcctgtaac
    33541 cctgcaacgc tggctcggga tagcgaagcg ttattaaaag caggatatac cattgcgcga
    33601 ctggcgatgc tggatatgtt cccacacacg ggacatctgg aatcgatggt acttttctcg
    33661 cgcgttaaat agttacgatt tgccgatttc ggcaggtctg gtccctaaag gagaggacga
    33721 tggttgcggt aagaagtgca catatcaata aggctggtga atttgatccg gaaaaatgga
    33781 tcgcaagtct gggtattacc agccagaagt cgtgtgagtg cttagccgaa acctgggcgt
    33841 attgtctgca acagacgcag gggcatccgg atgccagtct gttattgtgg cgtggtgttg
    33901 agatggtgga gatcctctcg acattaagta tggacattga cacgctgcgg gcggcgctgc
    33961 tattccctct ggctgatgcc aacgtagtca gcgaagatgt gctgcgcgag agcgtcggta
    34021 agtcggtcgt taaccttatt cacggcgtgc gtgatatggc ggcgatccgc cagctgaaag
    34081 cgacgcacac tgattctgtt tcctccgaac aggtcgataa cgttcgccgg atgttattgg
    34141 cgatggtcga tgattttcgc tgcgtagtca tcaaactggc ggagcgtatt gctcatctgc
    34201 gcgaagtaaa agatgcgccg gaagatgaac gtgtactggc ggcaaaagag tgcaccaata
    34261 tctacgcgcc gttggcgaac cgtcttggga ttgggcaact gaaatgggag ctggaagatt
    34321 actgcttccg ttatctccac ccgaccgaat acaaacgcat cgcaaaactg ttgcatgaac
    34381 gccgtctcga ccgcgaacac tatatcgaag agtttgtcgg ccatctgcgc gctgagatga
    34441 aagctgaagg cgttaaagcc gaagtgtatg gccgtccgaa acacatctac agcatctggc
    34501 gcaaaatgca gaaaaagaac ctcgccttcg atgagctgtt tgatgtgcgt gcggtacgta
    34561 ttgtcgccga gcgtttacag gattgttatg ccgcactggg gatagtgcac actcactatc
    34621 gccacctgcc ggatgagttt gacgattacg tcgctaaccc gaaaccaaac ggttatcagt
    34681 ctattcatac cgtggttctg gggccgggtg gcaaaaccgt tgagatccaa atccgcacca
    34741 aacagatgca tgaagatgca gagttgggtg ttgctgcgca ctggaaatat aaagagggcg
    34801 cggctgctgg cggcgcacgt tcgggacatg aagaccggat tgcctggctg cgtaaactga
    34861 ttgcgtggca ggaagagatg gctgattccg gcgaaatgct cgacgaagta cgtagtcagg
    34921 tctttgacga ccgagtgtac gtctttacgc cgaaaggtga tgtcgttgat ttgcctgcgg
    34981 gatcaacgcc gctggacttc gcttaccaca tccacagtga tgtcggacac cgctgcatcg
    35041 gggcaaaaat tggcgggcgc attgtgccgt tcacctacca gctgcagatg ggcgaccaga
    35101 ttgaaattat cacccagaaa cagccgaacc ccagccgtga ctggttaaac ccaaacctcg
    35161 gttacgtcac aaccagccgt gggcgttcga aaattcacgc ctggttccgt aaacaggacc
    35221 gtgacaaaaa cattctggct gggcggcaaa tccttgacga cgagctggaa catctgggga
    35281 tcagcctgaa agaagcagaa aaacatctgc tgccgcgtta caacttcaat gatgtcgacg
    35341 agttgctggc ggcgattggt ggcggggata tccgtctcaa tcagatggtg aacttcctgc
    35401 aatcgcaatt taataagccg agtgccgaag agcaggacgc cgccgcgctg aaacagcttc
    35461 agcaaaaaag ctacacgccg caaaaccgca gtaaagataa cggtcgtgtg gtggtagaag
    35521 gggtcggtaa cctgatgcac cacatcgcgc gctgctgcca gccgattcct ggagatgaga
    35581 ttgtcggctt cattacccag gggcgcggta tttcagtaca ccgcgccgat tgcgaacaat
    35641 tggcggaact gcgctcccat gcgccagaac gcattgttga cgcggtatgg ggcgagagct
    35701 actccgccgg atattcgctg gtggtccgcg tggtggctaa tgatcgtagt gggttgttac
    35761 gtgatatcac caccattctc gccaacgaga aggtgaacgt acttggcgtt gccagccgta
    35821 gcgacaccaa acagcaactg gcgaccatcg acatgaccat tgagatttac aacctgcaag
    35881 tgctgggtcg cgtgctgggt aaactcaacc aggtaccgga tgttatcgac gcgcgtcggt
    35941 tgcacgggag ttaatcttac atagctggat atggcgtcag ccgtatccag cgatatcttt
    36001 tactcgaagg tattacacct gacggacccg caattttcag gataattcaa tgaatcaaat
    36061 cgaccgtttg ctcaccatca tgcagcgcct gcgcgacccg gaaaacggct gcccgtggga
    36121 taaagagcag acatttgcca ccattgcgcc ttacaccctt gaagaaacct acgaggtgct
    36181 ggacgccatc gcccgtgaag attttgacga tctgcgcggt gaactgggcg atctgctgtt
    36241 ccaggtggtg ttttacgcac aaatagctca ggaagaaggg cgctttgact ttaatgatat
    36301 ttgcgctgct attagcgata aattagagcg tcgccatccg catgtttttg ctgacagttc
    36361 tgccgaaaat agtagtgaag tgcttgcccg ttgggagcaa atcaaaaccg aagagcgcgc
    36421 gcagaaagcg cagcattcgg cgctggacga tattcctcgt agtttaccgg ctttaatgcg
    36481 tgcgcaaaaa atccagaaac gttgcgccaa cgttggtttc gactggacga cgcttggtcc
    36541 ggtagtcgat aaagtctacg aagagatcga cgaggtgatg tacgaggcgc ggcaggctgt
    36601 tgtcgaccag gctaaactgg aggaggaaat gggtgacctg ctgtttgcca cggtcaatct
    36661 ggctcgtcat ttagggacaa aagcggaaat cgcattgcaa aaagcgaacg aaaaattcga
    36721 gcgtcgtttt cgcgaagtgg agcgtattgt tgccgcgcgt ggactggaaa tgacaggtgt
    36781 tgacctcgaa acaatggaag aagtctggca acaggtaaaa cggcaggaaa ttgatctcta
    36841 agggaattac gtggtcaagc gcgatttgtg tcatttttta aatgacaagc gcttgatttg
    36901 cgtcaaaaac atttacccca aaggggctat tttctcactc ctgatttcaa tagtgcgctg
    36961 gcgaagagga gggataatga aagtttgtgg cacaggtcat gttcgggtat actgctttcc
    37021 cgtcctggtt attccatcgt cttttcaacc taacttctca ggttcagcat gacaacgaac
    37081 tatatttttg tgaccggcgg ggtcgtatcc tctctgggta aaggcattgc cgcagcctcc
    37141 ctcgcagcca ttcttgaagc ccgtggcctc aatgtgacca tcatgaaact ggatccgtac
    37201 atcaacgtcg atcccggtac tatgagccca atccaacacg gggaagtgtt cgttactgaa
    37261 gacggcgctg aaaccgacct ggacctgggg cactacgagc gtttcattcg taccaaaatg
    37321 agccgccgca acaacttcac cacgggtcgt atctactctg acgttctgcg taaagaacgc
    37381 cgcggtgact atctcggcgc aaccgtacag gttattccgc acatcactaa cgctatcaaa
    37441 gagcgcgtgc tggaaggcgg cgaaggtcat gacgtagtac tggtcgaaat cggcggtact
    37501 gtcggtgata tcgaatccct gccgttcctc gaagcgattc gccagatggc tgttgaaatt
    37561 ggccgtgagc acaccctgtt tatgcacctg acgctggtgc cgtacatggc agcgtcaggt
    37621 gaagtcaaaa ccaaaccgac tcagcactct gtaaaagagc tgctttcaat cggtatccag
    37681 cctgatatcc tgatttgtcg ttcagatcgc gccgttccag cgaacgaacg tgcgaagatt
    37741 gcattgttct gtaatgttcc ggaaaaagcg gttatttctc tgaaagacgt cgattccatc
    37801 tataaaattc cgggcctgtt gaaatctcag gggctggacg attatatttg taaacgattc
    37861 agcttaaact gcccggaagc gaatctgtcc gaatgggaac aggttatctt cgaagaagcg
    37921 aatccggtaa gtgaagtcac cattggtatg gtcggcaaat acattgagct gccggatgca
    37981 tacaaatccg tgatcgaagc actgaaacac ggtgggctga agaatcgtgt cagcgtcaac
    38041 atcaaactga tcgattcaca agatgttgaa acgcgcggcg ttgaaatcct caaaggtctg
    38101 gacgcaatcc tcgtacctgg cggtttcggc tatcgtggcg tagaaggcat gattacgacc
    38161 gcgcgttttg cgcgtgagaa caatattcct tatctgggca tttgcctggg tatgcaggtg
    38221 gcgttaattg attacgctcg ccatgttgcc aacatggaga acgccaactc tacggaattt
    38281 gtgccagact gtaagtaccc ggttgtggcg ctgattaccg agtggcgcga tgaaaacggc
    38341 aacgttgaag ttcgtagcga gaagagcgat ctcggcggta ccatgcgtct cggcgcacag
    38401 cagtgccagt tggttgacga tagcctggtt cgccagctgt acaatgcgcc gacaattgtt
    38461 gagcgtcatc gtcaccgtta cgaagtcaac aacatgctgt tgaaacagat tgaagatgca
    38521 ggtctgcgcg ttgcgggccg ttccggggat gatcagttgg tcgagatcat cgaagttccg
    38581 aatcatccgt ggttcgtggc ttgccagttc catccggagt ttacttctac tccacgtgat
    38641 ggtcacccgc tgtttgctgg ctttgtaaaa gccgccagcg agttccagaa acgtcaggcg
    38701 aagtaagtaa aaaagttaga acggcaacgc gtaccctggg tacgcgttgt ttgtctggag
    38761 tttcagttta actagtgact tgaggaaaac ctaatgtcca aaatcgtaaa aatcatcggt
    38821 cgtgaaatca tcgactcccg tggtaacccg actgttgaag ccgaagtaca tctggagggt
    38881 ggtttcgtcg gtatggcagc tgctccgtca ggtgcttcta ctggttcccg tgaagctctg
    38941 gaactgcgcg atggcgacaa atcccgtttc ctgggcaaag gcgtaaccaa agctgttgct
    39001 gcggttaacg gcccgatcgc tcaggcgctg attggcaaag atgctaaaga tcaggctggc
    39061 attgacaaga tcatgatcga cctggacggc actgaaaaca aatccaaatt cggcgcaaac
    39121 gcaatcctgg ctgtatctct ggctaacgcc aaagctgctg cagctgctaa aggtatgccg
    39181 ctgtacgagc acatcgctga actgaacggc actccgggca aatactctat gccggttccg
    39241 atgatgaaca tcatcaacgg tggtgagcac gctgacaaca acgttgatat ccaggaattc
    39301 atgattcagc cggttggcgc gaaaactgtg aaagaagcca tccgcatggg ttctgaagtt
    39361 ttccatcacc tggcaaaagt tctgaaagcg aaaggcatga acactgctgt tggtgacgaa
    39421 ggtggctatg cgccgaacct gggttccaac gctgaagctc tggctgttat cgctgaagct
    39481 gttaaagctg ctggttatga actgggcaaa gacatcactc tggcgatgga ctgcgcagct
    39541 tctgaattct acaaagacgg taaatacgtt ctggctggcg aaggcaacaa agcattcacc
    39601 tctgaagaat tcactcactt cctggaagaa ctgaccaaac agtatccgat cgtttccatc
    39661 gaagacggtc tggacgaatc tgactgggac ggtttcgcat accaaaccaa agttctgggc
    39721 gacaaaatcc agctggttgg tgacgacctg ttcgtaacca acaccaagat cctgaaagaa
    39781 ggtatcgaaa aaggtatcgc taactccatc ctgatcaaat tcaaccagat cggttctctg
    39841 accgaaactc tggctgcaat caagatggcg aaagacgctg gctacactgc agttatctct
    39901 caccgttctg gcgaaactga agacgctacc atcgctgacc tggctgttgg tactgctgca
    39961 ggccagatca aaacgggttc tatgagccgt tctgaccgtg ttgctaaata caaccagctg
    40021 attcgtatcg aagaagctct gggcgaaaaa gcaccgtaca acggtcgtaa agagatcaaa
    40081 ggccaggcat aagtctgact ttatctgatt taaaaatgcc agccttcggg ctggcgtttt
    40141 ttatggttga gttaccaacg accggacgcg ccgccaccgc cagaagaacc gcccccgccg
    40201 ctaaatccgc cgccacttga gccgccaccg gaaccgctgt tgtctgaatg ataacttcta
    40261 ccagatgctt ttttctgaag tacacataaa caggtaaaga ccataatggt ggtgaaagta
    40321 aaaaagaaga aaaatacagc aatggaaaaa gttttatcgg agaacaggaa taaatctaaa
    40381 agatagattg ctgaaataca gacactgctt ttacatgcgc gacaaaaatt actgccttga
    40441 tgaaaaaacc agaaagggaa gaacatcact gcaaataccc aaaaaatagc aaagtagtaa
    40501 tgatcgctgg aagatgctga ttcactttct gaaggattaa ccgaatattg gtgttgtgaa
    40561 gtgagtcggt tattcaaagc gattatagct aactctaatc ctttagctaa ttgttgttgt
    40621 ttaaatgcgg gtatcatgtt gctacggatg atatctccag ccagagcatc ggttaccttt
    40681 tcttccagtc cataacctac ctggatgcgg acagtgcgat ccgaccaggc aacaatgatc
    40741 agtatcccat cattgcgttt ggcatctcct aaacgccaat tgtcaaaaac ccttgcagca
    40801 tattgttcaa ttgtctcgtc tttggttgtg ggaataatta atacagcaat ttgtacttgg
    40861 gtattattga aaatagattc tagcttgcgc gtcagttctt tcttttcttg tgagtttaag
    40921 ctactcgtaa gatccgtaac ttgttgctgt aattgtggga caatagttgg ttgggctgca
    40981 acaaaggaac acacgagtgt gaatattagt atgaaatagc gcattataaa tgtcctatta
    41041 aagctggata aataaattga cggcggtatc ggtaatttga ggttcg
//
LOCUS       DAFGPF010000033        39968 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFGPF010000033 DAFGPF010000000
VERSION     DAFGPF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39968
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.033"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            208..831
                     /gene="nfeR"
                     /locus_tag="LSX49_001966"
                     /gene_synonym="yqjI"
     CDS             208..831
                     /gene="nfeR"
                     /locus_tag="LSX49_001966"
                     /gene_synonym="yqjI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NfeR"
                     /protein_id="HBL7168383.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLCVNQSDITDAQIKKIIAVIDRAAFDITQLD"
     gene            complement(938..2458)
                     /gene="aer"
                     /locus_tag="LSX49_001967"
     CDS             complement(938..2458)
                     /gene="aer"
                     /locus_tag="LSX49_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerotaxis sensor receptor Aer"
                     /protein_id="HBL7168384.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTGKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFIVLAAMLWFVAAPVVTYIFCALVMLLGNACFEWQIVRPIENVASQ
                     ALKVATGERNSVEHLKRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQASAMVKHRASRLEDAVTVLH"
     gene            2876..4255
                     /gene="ygjG"
                     /locus_tag="LSX49_001968"
     CDS             2876..4255
                     /gene="ygjG"
                     /locus_tag="LSX49_001968"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417544.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HBL7168385.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAM
                     RTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMA
                     IEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALA
                     AMRVSVEEA"
     gene            complement(4297..4629)
                     /locus_tag="LSX49_001969"
     CDS             complement(4297..4629)
                     /locus_tag="LSX49_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBL7168386.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRIV"
     gene            4848..5831
                     /gene="ebgR"
                     /locus_tag="LSX49_001970"
     CDS             4848..5831
                     /gene="ebgR"
                     /locus_tag="LSX49_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HBL7168387.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLAIELTN
                     CYEHNGLPDIKNVTGILIVGKPTSALRAAACALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYINQGVNRIGFIGGEDLPGKADIREVAFAEYGRLKHVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKLKLRGTTR"
     gene            6015..9107
                     /gene="ebgA"
                     /locus_tag="LSX49_001971"
     CDS             6015..9107
                     /gene="ebgA"
                     /locus_tag="LSX49_001971"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HBL7168388.1"
                     /translation="MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLSL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLIGKQLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSARF
                     DFTVEQPQQWSAESPYLYHLVMTLKDADGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWENVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWFTT
                     LDDYTLHAEVRAEGETLATQQIKLCDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHPIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKM
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAMFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWHYTQENIHAAQHCNELQRSDDITLNLDHQLPGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSQASYEFGAGFFSTNLHSENKQ
                     "
     gene            9104..9553
                     /locus_tag="LSX49_001972"
     CDS             9104..9553
                     /locus_tag="LSX49_001972"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HBL7168389.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDS
                     LTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            9616..11049
                     /locus_tag="LSX49_001973"
     CDS             9616..11049
                     /locus_tag="LSX49_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL7168390.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            11183..12253
                     /gene="ygjJ"
                     /locus_tag="LSX49_001974"
     CDS             11183..12253
                     /gene="ygjJ"
                     /locus_tag="LSX49_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HBL7168391.1"
                     /translation="MKLITAPCRALLALPFCYAFSALGEEARPAEHDDTKTPEMISTS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYDSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLAEGITWMNGLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHDPSDQLFLMQYFYW"
     gene            12270..14621
                     /gene="ygjK"
                     /locus_tag="LSX49_001975"
     CDS             12270..14621
                     /gene="ygjK"
                     /locus_tag="LSX49_001975"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL7168392.1"
                     /translation="MKIKTILTPVACALLMSFSAHAANADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLISKDVQVEMILRFATPRTSLLETKITSDKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPMQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKYNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDRVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKAWLAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGDKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVANGGKRSDWTVKFAENRSQDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIIERGKGPESWSPLFNGEATQANADAVVKVMLDPKEFN
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFRHAK
                     GLTADGPIQENYNPLTGSQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            14847..16865
                     /gene="fadH"
                     /locus_tag="LSX49_001976"
     CDS             14847..16865
                     /gene="fadH"
                     /locus_tag="LSX49_001976"
                     /EC_number="1.3.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HBL7168393.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDANQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELTHEEILQLIDDFAHCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSM
                     LDLVEGGGTFAEMVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMIEVTGVTLKLNHTVT
                     ADQLQAFDETILASGIVPRVPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGF
                     DTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(16910..17326)
                     /gene="higA"
                     /locus_tag="LSX49_001977"
     CDS             complement(16910..17326)
                     /gene="higA"
                     /locus_tag="LSX49_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HigA"
                     /protein_id="HBL7168394.1"
                     /translation="MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLND
                     PENPLLDLVCAKITAWEESAPEFVEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIG
                     SKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID"
     gene            complement(17323..17637)
                     /gene="higB"
                     /locus_tag="LSX49_001978"
     CDS             complement(17323..17637)
                     /gene="higB"
                     /locus_tag="LSX49_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin HigB"
                     /protein_id="HBL7168395.1"
                     /translation="MHLITQKALKDAAEKYPQHKTELVALGNTIAKGYFKKPESLKAV
                     FPSLDNFKYLDKHYVFNVGGNELRVVAMVFFESQKCYIREVMTHKEYDFFTAVHRTKG
                     KK"
     gene            complement(17922..19058)
                     /gene="rlmG"
                     /locus_tag="LSX49_001979"
     CDS             complement(17922..19058)
                     /gene="rlmG"
                     /locus_tag="LSX49_001979"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HBL7168396.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGPVLILNDAFGALSCVLAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTPDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR"
     gene            19143..19646
                     /locus_tag="LSX49_001980"
     CDS             19143..19646
                     /locus_tag="LSX49_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBL7168397.1"
                     /translation="MSNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNALGLHTAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQDKI"
     gene            19723..20415
                     /locus_tag="LSX49_001981"
     CDS             19723..20415
                     /locus_tag="LSX49_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HBL7168398.1"
                     /translation="MLRAFARLLLRICFSRRTLKIGCLLLLIAGATIFIADRVMVNAS
                     KQLTWSDVNAVPARNVGLLLGARPGNRYFTRRIDSAAELYHAGKVKWLLVSGDNGRKN
                     YDEASGMQQALIAKGVPAKAIFCDYAGFSTLDSVVRANKVFSENHITIISQEFHNQRA
                     IWLAKQYGIDAIGFNAPDLNMKHGLYTQLREKLARVSAVIDAKILHRQPKYLGPLVMI
                     GPFSEHGCPAKE"
     gene            20494..21480
                     /locus_tag="LSX49_001982"
     CDS             20494..21480
                     /locus_tag="LSX49_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL7168399.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQTQLFLSHKIHVICEKPLASNQAE
                     VDAAIACARENQVVLFEAFKTAYLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFATLVDEHLVNHPGLAVSRITAKLLTEIRRQTGVIFPADNVKL"
     gene            21763..22728
                     /gene="alx"
                     /locus_tag="LSX49_001983"
     CDS             21763..22728
                     /gene="alx"
                     /locus_tag="LSX49_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HBL7168400.1"
                     /translation="MNTVGTPLLWGGFAVVVTIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRVG"
     gene            23052..24296
                     /gene="sstT"
                     /locus_tag="LSX49_001984"
     CDS             23052..24296
                     /gene="sstT"
                     /locus_tag="LSX49_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBL7168401.1"
                     /translation="MTTQHSPGLFRRLAHGSLVKQILVGLILGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVIF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(24300..24851)
                     /locus_tag="LSX49_001985"
     CDS             complement(24300..24851)
                     /locus_tag="LSX49_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HBL7168402.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQRRGIDPFKVEKTPSAVDERG"
     gene            complement(24934..26421)
                     /gene="uxaA"
                     /locus_tag="LSX49_001986"
     CDS             complement(24934..26421)
                     /gene="uxaA"
                     /locus_tag="LSX49_001986"
                     /EC_number="4.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL7168403.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGEHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIAHLHQLYSVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVEFANGKQTCNERNDFRELAIFKSGVTL"
     gene            complement(26436..27848)
                     /gene="uxaC"
                     /locus_tag="LSX49_001987"
     CDS             complement(26436..27848)
                     /gene="uxaC"
                     /locus_tag="LSX49_001987"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL7168404.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            28331..29629
                     /gene="exuT"
                     /locus_tag="LSX49_001988"
     CDS             28331..29629
                     /gene="exuT"
                     /locus_tag="LSX49_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexuronate transporter ExuT"
                     /protein_id="HBL7168405.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     VARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVDTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH"
     gene            29759..30535
                     /gene="exuR"
                     /locus_tag="LSX49_001989"
     CDS             29759..30535
                     /gene="exuR"
                     /locus_tag="LSX49_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HBL7168406.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQAADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDARTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            30880..31542
                     /locus_tag="LSX49_001990"
     CDS             30880..31542
                     /locus_tag="LSX49_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBL7168407.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKFEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            31546..31929
                     /gene="mzrA"
                     /locus_tag="LSX49_001991"
     CDS             31546..31929
                     /gene="mzrA"
                     /locus_tag="LSX49_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HBL7168408.1"
                     /translation="MQIPRMSLRQLAWSGAVLLLVSTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            32076..32444
                     /locus_tag="LSX49_001992"
     CDS             32076..32444
                     /locus_tag="LSX49_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HBL7168409.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHQKKIAKQKDEVAERQQDLAEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            32482..32787
                     /locus_tag="LSX49_001993"
     CDS             32482..32787
                     /locus_tag="LSX49_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HBL7168410.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            32790..33194
                     /locus_tag="LSX49_001994"
     CDS             32790..33194
                     /locus_tag="LSX49_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL7168411.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            33184..33483
                     /locus_tag="LSX49_001995"
     CDS             33184..33483
                     /locus_tag="LSX49_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HBL7168412.1"
                     /translation="MSSKVERERRKAQLLSQIQQQRLDLSATRREWLEATGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG"
     gene            33670..34062
                     /locus_tag="LSX49_001996"
     CDS             33670..34062
                     /locus_tag="LSX49_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HBL7168413.1"
                     /translation="MKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVP
                     GFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGMNSLMFMKN
                     LTISGGFLLLAITGPGAFSIDRLLNKKW"
     gene            34132..35118
                     /gene="yqjG"
                     /locus_tag="LSX49_001997"
     CDS             34132..35118
                     /gene="yqjG"
                     /locus_tag="LSX49_001997"
                     /EC_number="1.8.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionyl-hydroquinone reductase YqjG"
                     /protein_id="HBL7168414.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     KGGFAAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGASGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQPKIDELNGWIYDTINNGVYKAGFATSQQAYDEAVAKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            35401..35769
                     /locus_tag="LSX49_001998"
     CDS             35401..35769
                     /locus_tag="LSX49_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HBL7168415.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKLEQE"
     gene            complement(35803..36699)
                     /gene="yhaJ"
                     /locus_tag="LSX49_001999"
     CDS             complement(35803..36699)
                     /gene="yhaJ"
                     /locus_tag="LSX49_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HBL7168416.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIPKLFSGK"
     gene            36804..37505
                     /locus_tag="LSX49_002000"
     CDS             36804..37505
                     /locus_tag="LSX49_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HBL7168417.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASTGEVLLLSTQPGVSYS
                     EHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMSKQQLIASPEGGMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            37528..37692
                     /locus_tag="LSX49_002001"
     CDS             37528..37692
                     /locus_tag="LSX49_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312016.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168418.1"
                     /translation="MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(37801..39063)
                     /locus_tag="LSX49_002002"
     CDS             complement(37801..39063)
                     /locus_tag="LSX49_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBL7168419.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AISDAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNG
                     VVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSM"
     gene            complement(39091..>39968)
                     /locus_tag="LSX49_002003"
     CDS             complement(39091..>39968)
                     /locus_tag="LSX49_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="septum formation protein"
                     /protein_id="HBL7168420.1"
                     /translation="SDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALG
                     VSMVGMWHLYNVGSLPPLGLLMKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEV
                     ARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDG
                     AAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKIPAEKINENLVQRGIM
                     IFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLII
                     VTGLLLCVSPFLAFS"
BASE COUNT         9517 a        10481 c        10314 g         9656 t
ORIGIN      
        1 aagtgatttg tagcactgat atatctgtag tctgataaga cgcgcaacct cttatcaagc
       61 atcattgctc aatgccggat gcggcgtgaa cgccttatcc ggcctacatg ttgagtaaac
      121 ctgcgtttaa aaatcatttt tgtacttgca gtaatgctca tatcagatat aaattagata
      181 tatctaatta agcaaaagga ggctgatatg agccatcatc acgaagggtg ttgtaaacat
      241 gaaggccagc cacgccatga gggctgctgc aaaggtgaga agtcagaaca cgagcactgc
      301 ggacacggtc accagcatga acacggtcaa tgctgcggtg gtcgccacgg tcgcggcggc
      361 ggtcgtcggc aacgtttctt tggtcacggt gaattgcgtc tggtgattct ggatattctc
      421 tcgcgcgatg acagccacgg ttacgagttg attaaagcga ttgaaaatct gacccagggg
      481 aattacaccc caagcccggg cgtcatctac ccgacgctgg attttctgca ggagcagtcg
      541 ctgattacca tccgcgaaga ggaaggtggt aagaagcaga ttgcgctgac cgaacaaggc
      601 gcgcagtggc tggaagaaaa ccgcgaacag gtagagatga ttgaagaacg catcaaagcg
      661 cgttgcgttg gcgctgcgct gcgccagaac ccgcaaatga agcgggcgct ggataatttt
      721 aaagcggtgc tggatttatg cgtcaaccag agcgatatca ctgatgcaca aataaaaaag
      781 atcattgcgg tgatcgaccg cgccgctttt gatattaccc aactggatta atcaccgatt
      841 gccggatgcg gcgtacccta cacaccccgt aggcctgata agatgcgcca gcatcgcatc
      901 aggcattgtg ctccaaccgc cggatccggc ataccgatta atgcagcacc gtcaccgcgt
      961 cttccagtcg gctggcgcgg tgtttcacca tcgccgacgc ctgcgcactc tcttccacta
     1021 actcggcgtt tttctgggtg atcaggttaa gctcatccac tgcacgggtc aggctggaaa
     1081 gcccatcggc ctgttccagc gttgaatggc taatctgagc tatcaactgg gtgacgtttt
     1141 ttacctgcgc cacaatatct tccatcgtcc gtccggcggc gtgtacctgc tgcgaaccag
     1201 attgcacctt atcagcactg gcatcaatca gcttgcgaat atcgttggca gcattggcgc
     1261 tgcggctggc taaatgacgc acttcccccg ccaccactgc aaaacctttg ccctgttcgc
     1321 cggcacgcgc cgcttccacc gccgcattca gggccagaat attggtctga aacgcaatat
     1381 cgttaatcag cgaagtaatg gtgccaatgc gctgggtact gtcggcaata tcgtccattg
     1441 tcttgatcac cgtagtcatc gcctccccgc cctgcactgc cgcattactg gcggtgatag
     1501 aaagtttatc ggcagccgac gccgtggcag agttctgttt caccgacgcc gccatttggt
     1561 tcatggtcgc caccgtttgc tgaacgttat caactgtctg ctgggtatgt tcgttcagtt
     1621 catcggtgcc tttcgccagc gtctcactgc cgtttctgac actggacacc tggcttgaga
     1681 catcattaat tagccaacgg cacatcaggc caagctgccc taccgcgcgt aatgtcagcc
     1741 ccagctcatc gctgcgcttc agatgctcaa cactattacg ttctccggtc gccactttca
     1801 gtgcctggct ggcgacattt tctatcggac gtacaatttg ccattcaaaa caggcatttc
     1861 ccaacaacat cactaatgca cagaagatat acgtcaccac cggggcagca acaaaccaga
     1921 gcatggccgc cagcacgata aacatcaggg tcatcactcc acgcgcccgc cagcgaagcg
     1981 gtaatgaagg cagtttaccc agccagcctt tacgcaccac caggccttta tgaatacgct
     2041 taccggtacg tccggcattc agcgctttgt acagcggctc caccgccgcg atctcttcat
     2101 ccgtcgcccg ggtacgaatc gacatatagc cactgatttt tccctcgcgc accatcggta
     2161 ccgcattggc ccgcacccaa taatggtcgc catttttgcg gcgatttttc acgatgccgc
     2221 tccagggttc cccttttttc agggtgaacc acatatccgc aaacgccgct tttggcatat
     2281 ccgggtgacg caccatgttg tgcggttgcc cctgtaactc ctgcaaggta tagccgctca
     2341 cctgcacaaa agtgtcatta gcatgagtga tatagctttg cagatcggta gtggacatca
     2401 gagtggtgtc gtccgccagc ggggtatttt gctgggtgac atacggatga gaagacatgt
     2461 tcgcgtcctg tgcaggttat atggttgtta acttcttgtc agagtttatg tcggccccgc
     2521 tgcggttatc tttaaccaat taatttgatt tagatcgcaa tttgcgatta aagcacaaat
     2581 ctaattcctt gatttaaaat actttcactc tgttactata cgaaaacgtt aattatcttg
     2641 cccaaaaatc aggcaattat tgccctgaaa gcgtgcattt gcgcagcaat catcaaatcc
     2701 atacccgaca aaaaccgtgc aaaataacag caaatgttag caaatagcat taaatattgc
     2761 gcaaatgata accacatttg tgtttatccc gattttcgcg atcgcagccg gagtggcgca
     2821 atccctgcaa tacttaaatc ggtatcatgt gatacgcgag cctccggagc atattttgaa
     2881 caggttacct tcgagcgcat cagctttagc gtgcagcgcc cacgccctga atctcattga
     2941 aaagcgaacg ttggatcatg aggagatgaa agcacttaac cgggaggtga ttgaatactt
     3001 caaagagcat gtcaatccgg ggtttttaga gtatcgcaaa tctgttaccg ccggcgggga
     3061 ttacggagcc gtagagtggc aagcgggagg tttaaatacg cttgtcgaca cccagggaca
     3121 ggagtttatc gactgcctgg gaggttttgg aattttcaac gtggggcacc gtaatccagt
     3181 tgtggtttcc gccgtacaga atcaacttgc gaaacaaccg cttcacagcc aggagctgct
     3241 tgatccgtta cgggcgatgc tggcgaaaac ccttgcggcg ctaacgcccg gtaaactgaa
     3301 atacagcttc ttctgtaata gcggcaccga atccgttgaa gcggcgctga agctggcgaa
     3361 ggcttatcag tcaccgcgcg gcaagtttac ttttattgcc accagcggcg cgttccacgg
     3421 taaatcactt ggcgcgctgt cggccacggc gaaatcgacc ttccgcaaac cgtttatgcc
     3481 actgctgcca gggtttcgtc atgtaccgtt tggcaatatc gaagccatgc gcacggctct
     3541 taacgagtgc aaaaaaaccg gtgatgatgt tgctgcggtg atcctcgaac cgattcaggg
     3601 cgaaggtggc gtaattctgc cgccgccagg ctatctcacc gccgtgcgta agctgtgcga
     3661 tgagttcggc gcactgatga tcctcgatga agtacaaacg ggcatggggc gcacgggcaa
     3721 gatgttcgcc tgcgagcatg agaacgtaca gccggatatc ctttgtctgg caaaagcgct
     3781 cggcggcggc gtgatgccga ttggcgcaac catcgccact gaagaggtgt tctcagtcct
     3841 gttcgacaat ccgttcctgc acactaccac ctttggcggc aacccgctgg cctgtgcggc
     3901 ggcgctggcg accatcaatg tgttgctgga gcagaactta ccggctcagg ctgaacaaaa
     3961 aggcgatatg ttgctggacg gtttccgtca actggcgcgg gaatatcccg atctggtaca
     4021 ggaagcgcgt ggtaaaggga tgttgatggc gattgagttt gttgataacg aaatcggcta
     4081 taactttgcc agcgagatgt tccgccagcg cgtactggtg gccggaacac tcaacaacgc
     4141 taaaacgatc cgcattgaac cgccactgac actgaccatt gaacagtgtg aactggtgat
     4201 caaagcggcg cgtaaggcgc tggcggccat gcgagtcagt gtcgaagaag cgtaatatca
     4261 aatcggatgg cgatacgacg tcgccatccg atctttttat acgatacgta cgcccgcagg
     4321 catcatccgc tccggcgtta acagcacgct ttcactgccg tcatcggttt ccgcacacaa
     4381 cagcatgcat tccgacgttt caccgcgcat tttcgctttt tgcagattgc ataagaccac
     4441 cactgttttt cccatcagct cttcttcgct gtagtacggc accagactgg tcacggtttg
     4501 cagcgttttt tcccccacat caacctgtac gatgtacagc ttgtcggcgt tttcatggcg
     4561 tttcacttcc acaatctttc cgacgcgcat ttccagacgt gcaaaatcag cgtaagccac
     4621 ggtttccatt gtttcctccc ttcaagtaaa attttactaa actatagcaa aagtttttct
     4681 caatcctgta ggctaaaaat ggagaatgca ggcgtgatca cattcgtgag ccgctgtgtt
     4741 accgtcacag cgtcaaagaa acgcgcttta tttactgaaa acaggtgacc cgataagcac
     4801 ttcctctaca atgggggcgc acatcaggga aagtaaaaaa ggtaaacatg gcaacactaa
     4861 aagacatcgc aatcgaagct ggcgtatccc tggcgacagt atccagggtc ttgaatgacg
     4921 atccgacatt gaatgtgaaa gaagagacga aacatcgcat tctcgagatc gccgaaaagc
     4981 tggagtacaa gaccagtagc gcccgtaaac tccagacagg cgcagtcaac caacaccata
     5041 ttctggctat ctacagctac caacaggagt tggagatcaa cgatccttac tatctggcga
     5101 tccgccacgg cattgaaact cagtgcgaaa agctggcgat cgaactgacc aactgttatg
     5161 aacacaacgg cttaccagac attaaaaacg tcaccggtat tttaattgtc ggcaaaccca
     5221 cgtccgccct gcgcgccgcc gcctgtgcgt tgaccgacaa tatctgtttt atcgactttc
     5281 acgaacccgg cagcggttac gatgcggtgg atatcgatct ggcacgtatc agtaaagaaa
     5341 tcatcgattt ctatatcaat cagggcgtta atcgtattgg ttttattggc ggtgaagact
     5401 tacccggcaa ggcggatatt cgtgaggtcg cctttgcgga atatggtcgt ctgaaacacg
     5461 tggtacgcga agaggatatc tggcgcggcg gtttttccag ttcgtcgggc tatgaactgg
     5521 caaaacagat gctggcgcgg gaagactatc cgaaggcact gtttgttgct tccgattcca
     5581 ttgctatcgg cgtactgcgg gcaattcatg aacgtggcct gaacatccca caggatattt
     5641 cgcttatcag cgttaacgat atccccaccg cgcgatttac ctttccgccg ctctccaccg
     5701 tgcgcatcca ttccgagatg atgggaagtc agggcgttaa cctggtgtat gaaaaagccc
     5761 gcgatggtcg cgcgctgccg ctgttggtct tcgttcccag caaattaaaa ctgcgcggca
     5821 cgacccgtta aatcccctta cacactgtcc ggcaatcgtt tttgccggac agtgctgccg
     5881 tttattttcg tgatccagtt aaagtaaatg catttacctg ctatttttta gtaaaaattt
     5941 tactaaactc cccagcaatt acacaaacta ccatcaccat aaatggttcc gatttctctc
     6001 taccgggagg ccctatgaat cgctgggaaa acattcagct cacccacgaa aaccgacttg
     6061 cgccgcgtgc gtactttttt tcatatgatt ctgttgcgca agcgcgtacc tttgcccgcg
     6121 aaaccagcag cctgtttctg tccttaagcg gtcagtggaa tttccacttt tttgaccatc
     6181 cgctgcaagt accagaagcc ttcacctctg agttaatggc tgactggggg catattaccg
     6241 tccccgccat gtggcaaatg gaaggtcacg gcaaactgca atataccgac gaaggttttc
     6301 cgttccccat cgatgtgccg tttgtcccca gcgataaccc aaccggtgcc tatcaacgta
     6361 ttttcaccct cagcgacggc tggcagggta aacagacgct gattaaattt gacggcgtcg
     6421 aaacctattt tgaagtctac gttaacggtc agtatgtggg gttcagcaaa ggcagtcgcc
     6481 tgaccgcaga gtttgacatc agcgcgatgg ttaaaaccgg cgacaacctg ttgtgtgtgc
     6541 gcgtgatgca atgggcggac tctacctacg tggaagacca ggatatgtgg tggtcggcgg
     6601 ggatcttccg cgatgtttat ctgatcggaa aacaactcac gcacattaac gatttcaccg
     6661 tgcgcaccga ctttgacgaa gcctattgcg atgccacact ttcctgcgaa gtggtgctgg
     6721 aaaatctcgc cgcctcccct gtcgtcacga cgctggaata taccctgttt gatggcgaac
     6781 gcgtggtgca cagcagcgcc attgatcatt tggcaattga aaaactgacc agcgcccgct
     6841 ttgattttac tgtcgaacag ccgcagcaat ggtcagcaga atccccttat ctttaccatc
     6901 tggtcatgac gctgaaagac gccgacggca acgttctgga agtggtgcca caacgcgttg
     6961 gcttccgtga tatcaaagtg cgcgacggtc tgttctggat caataaccgt tatgtgatgc
     7021 tgcacggcgt caaccgtcac gacaacgatc atcgcaaagg ccgcgccgtt ggaatggatc
     7081 gcgtcgagaa agatctccag ttgatgaagc agcacaacat caactccgtg cgtaccgctc
     7141 actacccgaa cgatccgcgt ttttacgaac tgtgtgatat ctacggcctg tttgtgatgg
     7201 cggaaaccga cgtcgaatcg cacggctttg ctaatgtcgg cgatatcagc cgtattaccg
     7261 acgatccgca gtgggaaaac gtctacgtcg agcgcattgt tcgccatatt cacgcgcaga
     7321 aaaaccatcc gtcgatcatc atctggtcgc tgggcaatga atccggctat ggctgtaaca
     7381 tccgcgcgat gtaccatgcg gctaaggcgc tggatgacac gcgactggtg cactacgaag
     7441 aagatcgcga tgctgaagtg gtcgatatta tttccaccat gtacacccgc gtgccgctga
     7501 tgaatgagtt tggtgaatac ccgcatccga agccgcgcat catctgtgaa tatgctcatg
     7561 cgatggggaa cggaccgggc gggctgacgg agtaccagaa cgtcttctat aagcacgatt
     7621 gcattcaggg acattatgtc tgggaatggt gcgaccacgg gatccaggcg caggatgaca
     7681 acggcaatgt ctggtataaa ttcggcggcg actacggcga ctatcccaac aactataact
     7741 tctgtcttga tggtttgatc tattccgatc agacgcctgg gccgggcctg aaagagtaca
     7801 aacaggttat cgcgccggta aaaatccacg cgttggatct gactcgcggc gagttgaaag
     7861 tcgaaaataa actgtggttt accacgctgg atgactacac cctgcacgca gaggtgcgcg
     7921 ccgaaggtga aacgctcgcg acgcagcaga ttaaactgtg cgacgttgca ccgaacagcg
     7981 aagccccctt gcagatcacg ctgccgcaac tggacgctcg tgaagcgttt ctcaacatta
     8041 cggtgaccaa agattcccgc acccgctaca gcgaagccgg acaccctatc gctacttatc
     8101 agttcccgct gaaggaaaat accgcgcagc ctgtaccttt cgcgccaaat aatgcgcgtc
     8161 cgctgacgct ggaagacgat cgtttgagct gcaccgttcg cggctacaac ttcgcaatca
     8221 ccttctcaaa aatgagtggc aaaccgacat cctggcaggt gaatggcgag tcgctgctga
     8281 cccgcgagcc aaagatcaac ttcttcaagc caatgatcga caaccacaag caggagtacg
     8341 aagggctgtg gcagccgaat catttgcaga tcatgcagga acatctgcgc gactttgccg
     8401 tagaacagag cgatggtgaa gtgttgatca tcagccgcac ggttattgcc ccaccggtgt
     8461 ttgacttcgg gatgcgctgc acctacatct ggcgcatcgc tgccgatggc caggttaacg
     8521 tggcgctttc cggcgagcgt tacggcgact atccgcacat cattccgtgc atcggtttca
     8581 ccatggggat taacggcgaa tacgatcagg tggcgtatta cggtcgtgga ccgggcgaaa
     8641 actacgccga cagccagcag gctaacatca tcgatatctg gcgcagcacc gtcgatgcca
     8701 tgttcgagaa ctatcccttc ccacagaaca acggcaaccg tcagcatgtc cgctggacgg
     8761 cactgactaa ccgccacggc aatggtctgc tggttgttcc gcagcgccca attaacttca
     8821 gtgcctggca ctacacccag gaaaacatcc acgcagccca gcactgtaac gagctgcagc
     8881 gcagtgatga catcaccctg aatctcgacc accagttgcc tggcctcggc tccaactcct
     8941 ggggcagcga ggtgctggac tcctggcgcg tctggttccg tgacttcagc tacggcttta
     9001 cgttgctgcc ggtttctggc ggagaagcta ccgcgcaaag ccaggcgtcg tatgagttcg
     9061 gcgcagggtt cttttccacg aatttgcaca gcgagaataa gcaatgagga tcatcgataa
     9121 cttagaacag ttccgccaga tttacgcctc tggcaagaag tggcaacgct gcgttgaagc
     9181 gattgaaaat atcgacaaca ttcagcctgg cgtcgcccac tccatcggtg actcattgac
     9241 ttaccgcgtg gagacggact ccgcgaccga tgcgctattt accgggcatc gacgctattt
     9301 tgaagtgcat tactacctgc aagggcagca aaaaattgaa tatgcgccga aagagacatt
     9361 acaggtagtg gaatattatc gtgatgaaac tgaccgcgaa tatttaaaag gctgcggaga
     9421 aaccgtagag gtccacgaag ggcaaatcgt tatttgcgat atccatgaag cgtatcggtt
     9481 tatctgcaat aacgcggtca aaaaagtggt tctcaaagtc accatcgaag atggttattt
     9541 ccataacaaa taaaaactac ggcggcaaaa ggagtttgcc gccaccgcta ccctactcat
     9601 tttcggagat gtgttatgtc tgataccaaa cgtaatacaa tcggcaaatt cggcttgctc
     9661 tcgctgactt ttgccgccgt ttacagcttt aacaacgtta tcaataataa tattgagctt
     9721 ggactggcct cggcaccgat gtttttcctc gcaacaattt tttattttat tcccttctgt
     9781 ctgatcatcg cagaatttgt ttcgttaaat aaaaactcgg aagccggtgt ctacgcgtgg
     9841 gtaaaaagtt cgctgggcgg acgttgggca tttattactg cctataccta ctggttcgta
     9901 aacctgttct ttttcacctc attattgccg cgcgttattg cttacgcctc gtatgcattc
     9961 ctcggctacg aatatattat gacgccggtt gccaccacca ttatcagtat ggtgctgttc
    10021 gccttttcca cctgggtttc taccaacggg gcgaaaatgc tggggccaat tacctccgtc
    10081 acttcaacgc tgatgctgct gttaacgctc tcctacattt tactggcagg tacggcactg
    10141 gttggcggcg tacagcctgc tgaccccatc actgttgacg cgatgatccc aaactttaac
    10201 tgggcgttcc tcggcgttac cacctggatc tttatggctg caggtggcgc ggagtccgtc
    10261 gcggtgtacg ttaacgacgt caaaggcggt tcgaaatcgt tcgttaaagt gatcatcctc
    10321 gccgggattt ttattggcgt actgtactcc gtctcctcgg tactgattaa cgtcttcgtc
    10381 agcagcaaag agttgaagtt taccggcgga tcggtacagg tattccacgg catggcggcg
    10441 tattttggtc taccggaagc actgatgaat cgctttgtcg gtctggtgtc ctttaccgcg
    10501 atgttcggtt ccctgctgat gtggacggca acgccggtga aaattttctt ctccgaaatt
    10561 ccggaaggca tctttggtaa gaaaaccgtc gaactgaacg aaaacggcgt tccggcgcgc
    10621 gcagcgtgga tccagttcct gatcgtcatc ccgctgatga ttatcccgat gctcggttcc
    10681 aataccgtgc aggatctgat gaatactatt attaatatga ctgctgcagc gtccatgctt
    10741 ccgccgttat tcatcatgct ggcttacctg aatttacgcg ccaaattaga tcacctgcca
    10801 cgcgatttcc gtatgggctc ccgccgcacc ggtattatcg ttgtttcaat gctgattgcg
    10861 atatttgcag tagggtttgt cgcttcgaca ttcccgactg gcgcgaatat tctgaccatc
    10921 attttttata acgtcggcgg tattgttatc ttcctcggct ttgcgtggtg gaaatacagt
    10981 aaatatataa agggattaac ggctgaagag cgccatattg aagcgacgcc agccagcaat
    11041 gttgattaag cagaataata aaaaatgagc aggcattttc cctcttcctg gatggggaga
    11101 gggaaaatag tttctgcctt tatattttta taattacaac gataaaaggc tgtacttttt
    11161 ctttagctca tggattaaca caatgaaatt aatcactgca ccatgcagag cattacttgc
    11221 cctgcctttt tgctacgctt tttctgcact tggcgaagaa gcacgtccgg cagaacatga
    11281 cgacacaaaa acccccgaaa tgatctcgac atcttctcct tcatttcgtt tttacggcga
    11341 attaggggtt ggtgggtata tggatttaga gggtgagaat aaacataaat acagcgacgg
    11401 cacctatatt gaaggtggcc tggagatgaa gtacgactcc tggttcggcc tgatttacgg
    11461 cgaaggctgg accgtgcagg ccgaccacga cggtaatgcc tgggtgcctg accatagctg
    11521 gggtggtttc gaaggtggga ttaaccgttt ctatggcggt tatcgtacca atgatggcac
    11581 cgaaatcatg ctcagtctgc gtcaggattc ctcgctggat gacctgcaat ggtggggcga
    11641 tttcacgccc gatctgggct acgtcattcc caatacccgc gacattatga ctgcgctgaa
    11701 ggtacagaac ttaagcggca actttcgtta tagcgttacc gccacacctg ccggacatca
    11761 tgacgaaagc aaagcctggc tacattttgg caagtacgat cgctacgacg acaaatacac
    11821 ctatccggca atgatgaacg gttacatcca gtatgacctt gcagaaggta tcacctggat
    11881 gaacggtctg gaaatcaccg acggcacagg ccaactctat ctcacgggcc tgcttacccc
    11941 taactttgcc gctcgcgcct ggcaccatac cggacgcgcc gacgggctgg acgtaccggg
    12001 aagtgaaagt gggatgatgg tgagcgccat gtatgaagcg ttaaagggcg tttatctctc
    12061 caccgcttac acctacgcca aacatcgccc tgaccacgct gacgatgaaa ccacctcttt
    12121 catgcagttt ggtatctggt acgaatacgg cggcggacgt ttcgcaacgg cttttgatag
    12181 ccgcttctac atgaaaaatg cctctcacga tcccagcgac caactcttcc tgatgcaata
    12241 tttttactgg taataaggac agtaatctca tgaaaatcaa aactatttta acaccagtag
    12301 cctgtgctct gctgatgagc ttttccgccc atgccgctaa cgctgacaat tataaaaacg
    12361 tgattaaccg tactggcgcg ccgcagtaca tgaaggatta cgattacgac gatcaccagc
    12421 gttttaatcc gtttttcgat ctcggagcct ggcatggtca tctgttgcca gacggcccga
    12481 acactatggg cggctttcca ggcgttgcgt tgttgacgga agagtacatc aactttatgg
    12541 ccagcaattt cgaccgcctg accgtctggc aggacggcaa gaaagtcgat ttcacgctgg
    12601 aggcatacag tattcccggc gcgctggtgc aaaagttgat atcgaaagat gtacaggtcg
    12661 aaatgattct gcgcttcgcc acgccgcgca catcactact ggaaaccaaa atcaccagcg
    12721 ataaaccgct ggatctggtg tgggatggcg aactgctgga aaaactggaa gcgaaagaag
    12781 ggaaaccgct ttccgataaa accattgctg gcgagtaccc tgactatcag cgcaaaatca
    12841 gcgccacccg cgatggcctg aaagttacct ttggcaaagt gcgcgccacc tgggatctgc
    12901 tgacctccgg tgaatcagaa tatcaggtgc ataaatcatt accgatgcag actgaaatca
    12961 acggcaatcg ctttaccagt aaggcgcata tcaacggatc gacgacgctc tataccacct
    13021 attcccatct gctgaccgct caggaagtta gcaaagagca aatgcagatc cgcgatattc
    13081 tggcgcgtcc ggcgttttat ctcaccgcct cgcagcaacg ttgggaagaa tacctgaaga
    13141 aaggattaac caatccggat gcgacgccgg aacagacgcg cgtcgcggtg aaagccatcg
    13201 aaacgctcaa cggtaactgg cgatcgccgg gcggtgcggt gaaatataac accgtcacgc
    13261 cgtcggtgac cgggcgctgg ttctccggca accagacctg gccgtgggat acctggaagc
    13321 aggcgtttgc gatggcgcat ttcaatccgg acatcgccaa agagaatatc cgcgcggtct
    13381 tctcctggca gatccagcca ggcgaccgcg tgcgtccgca ggatgtgggc tttgtccccg
    13441 acctgatagc gtggaacctt agccccgagc gtggcggcga tggcggcaac tggaacgaac
    13501 gtaataccaa acccagcctt gccgcctggt cagtaatgga agtgtataac gtcacccagg
    13561 ataaggcctg gttggcagag atgtacccga agctggtggc ctatcacgac tggtggttac
    13621 gtaaccgcga tcacaacggc aacggcgtgc cggaatatgg cgcgacccgc gacaaagccc
    13681 acaacaccga gagcggcgag atgctgttta cggtgaaaaa aggcgacaaa gaggagacgc
    13741 agtctgggct gaacaactac gcccgtgtgg tggagaaagg ccagtacgac agtctggaaa
    13801 ttccggcaca ggttgctgcg tcgtgggaat caggtcgtga tgacgccgcc gttttcgggt
    13861 ttatcgacaa agaacagctg gataaatatg tcgctaacgg cggcaaacgt agcgactgga
    13921 cggtgaaatt cgccgaaaac cgcagtcagg acggaacgtt gctgggctac tcgctattgc
    13981 aggagtcggt ggatcaggcc agctatatgt acagcgataa ccattatctg gcggagatgg
    14041 cgacgattct cggtaagccg gaagaggcca aacgctatcg tcagttagca caacagctcg
    14101 cggactacat caacacttgt atgttcgacc cgactacaca gttctactat gacgtgcgta
    14161 ttgaagataa accgctggcg aacggctgcg cgggcaaacc gattattgag cgcggtaaag
    14221 ggccggaaag ctggtcgccg ctgtttaacg gtgaggcaac gcaggccaat gccgacgcgg
    14281 tggtgaaggt gatgctggat ccgaaagaat tcaacacctt tgtcccgctg ggaacggcgg
    14341 cgttaaccaa tccggctttt ggcgcggata tctactggcg cgggcgcgta tgggtggatc
    14401 agttctggtt tggtctgaaa gggatggagc gttacggtta tcgtgatgat gccctgaagc
    14461 tggcggatac gttcttccgg cacgccaaag gattaaccgc cgatggccca attcaggaga
    14521 attacaaccc gctcactggc tcgcaacaag gcgcaccaaa tttctcctgg agtgccgcgc
    14581 atttgtatat gttgtataac gattttttcc gtaagcagta atttgcaacg gctggcggat
    14641 gcggcgtgaa cgccttatcc gccctacatg tgcaatcccc caggccggat aaaacgcggc
    14701 aagcgtcgca tccggcgtta ccaccgggcg tattcttttt gaatcccatc acaaaccccg
    14761 cactcccctt ttcccttttc tccggcgacg gctaaattag aactcatccg accacataac
    14821 aattatttta catactggac aattttatga gctacccgtc gctgttcgcc ccgctggatt
    14881 taggttttac cacgttaaaa aaccgcgtgt tgatgggctc aatgcacacc gggctggagg
    14941 agtacccgga cggcgctgaa cggctggcag cgttttatgc cgaacgcgcc cgtcacggcg
    15001 tggcgttgat tgtcagcggc ggtatcgcac cagatttaac aggcgttggc atggaaggcg
    15061 gtgcaatgct caatgacgcc aaccagatcc cacaccatcg caccattacc gaagccgtac
    15121 atcaggaagg cggcaaaatc gccctgcaaa ttttgcatac cgggcgctac agctaccaac
    15181 cgcatctggt cgctccctcc gcattgcagg cccccatcaa ccgtttcgtt cctcacgaac
    15241 tcacccatga agagatcctg caactgatcg acgatttcgc ccactgcgcg caattggcac
    15301 gggaggcagg atacgacggt gtagaggtga tggggtccga agggtatttg atcaacgaat
    15361 ttctgacgct gcgcaccaat cagcgtagtg accagtgggg cggcgattac cgcaaccgga
    15421 tgcggtttgc cgtagaagta gtgcgtgcgg tgcgcgaacg tgtcggcaac gacttcatta
    15481 ttatctaccg tttgtcgatg ctcgacctgg tcgaaggcgg cggtactttt gccgaaatgg
    15541 tagagctggc gcaggccatt gaagcggcgg gcgcgaccat tatcaacacc ggcattggct
    15601 ggcatgaagc gcggattccg accatcgcca cgcccgtgcc gcgcggcgcc tttagctggg
    15661 tcacgcgcaa actgaaaggg cacgtttcgc tgccactggt gaccaccaac cggattaacg
    15721 atccgcaggt tgccgacgac attctctcgc gcggtgatgc ggacatggta tcgatggcgc
    15781 gaccgtttct cgctgatgcg gagctgctat caaaagcgca atcgggacga gccgatgaga
    15841 tcaacacttg tattggctgc aaccaggcct gtctcgatca gatcttcgtt ggcaaagtca
    15901 cctcgtgcct ggtgaatcct cgcgcctgcc acgaaaccaa aatgccaatc cttcctgccg
    15961 tgcagaaaaa aaatctggcg gtggtcggtg cgggacctgc tgggctggcg tttgccatta
    16021 acgcggcggc gcgtgggcat caggtaacat tgtttgatgc gcacagcgag atcggcgggc
    16081 agtttaatat cgccaaacag atccccggca aagaggagtt ttacgaaacg ctgcgctatt
    16141 accgccggat gatcgaagtg acgggtgtaa cgctaaaact caatcacacc gtgacggcgg
    16201 atcagttaca ggcgttcgat gaaacgatcc tcgccagtgg gatcgtgccg cgcgttccgc
    16261 ctatcgacgg gatcgatcat ccgaaggtac tgagttatct cgatgtactg cgcgacaaag
    16321 cgccggtggg caacaaagtt gccatcatcg gttgtggcgg aattggtttt gatacggcga
    16381 tgtatttaag tcagccgggc gaatccacca gccagaatat cgccgggttc tgtaatgagt
    16441 ggggaatcga cagtagcctg caacaggccg gaggtttgag tccgcaaggc atgcaaatcc
    16501 cccgtagccc acggcagatt gtgatgctcc agcgcaaagc cagcaaacca ggacaagggt
    16561 taggcaaaac caccggctgg atccatcgca ccaccctgct ctcacgcggc gtgaaaatga
    16621 tcccaggcgt aagttaccag aagatcgacg atgacgggct gcatgtagtg atcaacggcg
    16681 aaacgcaggt actagcagtg gacaatgtgg tgatctgcgc ggggcaagag ccaaaccgcg
    16741 cattggcgca accgctgatt gatagtggga aaactgtgca tttaattggc ggctgcgatg
    16801 tagctatgga gctggacgca cggcgggcaa ttgcccaggg aacacggctg gcgctggaga
    16861 tttaaatcgt tgtttgaagc gccggatgcg acgcatccgg cacgtcgcgt taatcaataa
    16921 acaaggcggg agaaataccg aatcgcgttg ccagtttttt agcgtgttcc agcgttaatt
    16981 tccttttccc gctcaaaacg cgtgacacca tcgatttact gcctatttcc ggaagatcgg
    17041 aaagggttaa accatattga tccataaggg tacgaatcac ggctataccg ccaggcatgg
    17101 cttgagccat ggcattaaat tccacaaatt cgggcgctga ttcttcccac gcggttattt
    17161 tggcacacac cagatccagt aaggggtttt caggatcgtt gagcagcaga tgatctacca
    17221 gttccagcgc ctgggtgtat tgttcctcgt tctgaatacc cgccagaaaa ggtgccacag
    17281 cagttagctt ttctcctgct tgcaagatgt cggcaatcgc aatcattttt tccccttagt
    17341 acgatgaacg gcggtaaaga aatcgtattc tttatgcgtc ataacttcac gtatgtagca
    17401 cttttgcgat tcaaaaaaga ccattgctac aacacgtaat tcattgcccc cgacattgaa
    17461 aacataatgc ttatccagat atttgaagtt atccagagaa gggaatactg cttttaatga
    17521 ctcaggtttt ttgaaatatc ccttagcaat cgtgttcccc agagccacca actccgtttt
    17581 atgttgcggg tatttttccg cagcatcttt caatgctttt tgagttatca ggtgcattct
    17641 tcatcacgtc cgttgacaaa ttggcaatat gataacatcc gttgacagat tggcaacgaa
    17701 tgaatttatc tgtgtgacgg aagaataaac gtagaaaaac gctaaacaag agaatgtaga
    17761 ggatggtgac aggaattttt tgttttatgg aagcgcgatt ccagaactgg gcagacattg
    17821 ccggatgcga cgcttgccgc gtcttatccg acctgggggt aatgtgctga acgtatgccg
    17881 gataaggcgt ttacgccgca tccggcaggt aaccctcaat cttaccgacg acgccccagc
    17941 ttcactgctt tcagcaccac aaatttatta ttcgtggcga tggtggtgca gttgccgaaa
    18001 attttcttca gtttatggaa gtaatccaag tgacggttgg caacgatata cagctcgccg
    18061 ttgattttca ggcagcggcg ggcgtggtgg aacatctccc aggcgacgtt atcggtcagc
    18121 gcatgttgct gatgaaacgg cgggttgcag agcacagcat taaaacggaa aggctccacg
    18181 ccggaaagcg cgttgttgat cataaactcg cagcgatcca gtgcctcggg catgttggtt
    18241 tcaacgttca aacggctgga agcaaccgcc atcggtgatt catcgacaaa caccactttc
    18301 gcctgcgggt ttttatcgag caatgtcagg ccaataacgc cattaccgca accgagatcg
    18361 acaatctcac cttcgagatt ctctggcaga tgttgcataa agaagcgcgc gccaatatcc
    18421 agcccggtgc gggagaagac attcgcatgg ttgtggatag tccagtcagt accttccagc
    18481 ttccagctaa cggtctgcgg cgcatcggcc aacggcggtt cgttgaaggt gcagttaatc
    18541 aggcgcgctt tcttccatgc cagcgtggtg gtggtcgggc cgagcacttt ttcgaacaat
    18601 tccagcgtgg aagtgtgaat gtcacgggct ttggcaccag caataatgcg cgtatctggc
    18661 gtgaccactt tgcgcagcgc gcgcagttgt tgttccagca atgccagtgt tttcggcact
    18721 ttgatcagca ccacacccgg ctgttgcggg tagtcggcgg tgctgtcgag aaacttcacg
    18781 ctcgactcat caatcccgtt gaggcgtaaa ttctcgcgcg tggccagttc actgatgtat
    18841 gagtcgccaa tgctgtacgg cttatgttcc gccagcacac agcttaacgc accaaaagca
    18901 tcattcagga tcaacaccgg gccgcggatt tctgtgtcgt ccaactgttg cagcaaatac
    18961 tcatccgccg cttcccacgc ctgtagcggg ttaacgtcat ccgtcgccgg aaaacgttgt
    19021 agtgtcagtg aacggaaacc gttgtctaag tggctcatcg gccctcctga atgataaaat
    19081 ttcgacgttg cccctgaaaa gggtgcgtga gtataccctt tttctctttt tcgtgggcgg
    19141 ttatgagcaa tcttacttat cttcagggtt atcccgagca gctactttcc caggtgcgaa
    19201 cgctgattaa cgaacagcgt ctgggcgatg tgctggcaaa acgttatccg ggaacacacg
    19261 actacgccac cgataaagcc ctctggcaat atactcagga tcttaaaaat cagtttctgc
    19321 gcaatgcccc gccgatcaat aaagtgatgt atgacaataa gatccacgtg ctgaaaaacg
    19381 cgctcgggtt acatactgcc gtttcgcgtg tgcagggcgg caagctgaaa gcaaaagcag
    19441 agatccgcgt cgctaccgtg tttcgcaacg cgccggaacc gtttttgcgc atgatcgtgg
    19501 tgcacgagct ggcgcacctg aaggagaaag agcataacaa agcgttttac cagttgtgct
    19561 gtcatatgga accgcagtac caccagcttg agttcgacac ccggctgtgg ctaacgcagt
    19621 tgtcgcttgg gcaggacaaa atctgaaaat gatgtcaggc gttatttttt cctcctttag
    19681 cgcctaaaat cgatctcctc cctttcgtta aggataacga ccatgctgcg cgcatttgcc
    19741 cgccttcttc ttcgtatttg tttttctcgc cggactctta aaattggctg tttattgttg
    19801 cttatagcag gagcgaccat ttttattgcc gatcgcgtta tggtcaacgc cagcaagcag
    19861 ctgacctgga gtgatgtcaa cgccgttccg gcgcggaacg tgggtttatt gctgggggcg
    19921 aggccgggta atcgctactt tacccgacgt attgatagcg ccgcagagtt gtaccacgcc
    19981 ggaaaagtga aatggctatt ggtgagcggc gataatggac gtaaaaatta cgatgaagcg
    20041 tcaggaatgc agcaagcctt gatcgctaaa ggcgtaccgg caaaagccat cttctgcgac
    20101 tatgccggat tctcaacgct tgattcggtg gtgcgtgcca acaaggtgtt tagtgaaaac
    20161 catatcacca ttatctcgca agaatttcat aaccaacgcg ccatctggct ggcaaaacag
    20221 tatggtatcg atgctatcgg ttttaacgcg ccagacctga atatgaagca cggtttatat
    20281 actcaactgc gggaaaaact tgccagagtc agcgcggtga ttgatgcgaa aatcctccat
    20341 cgccagccga aatatctcgg gccgttggtt atgattgggc cgtttagtga gcatggctgt
    20401 ccggcaaaag aataatgcgt atctgcgcac gtcgaagata aaaaaggcgt gctacagtga
    20461 cgacagaatc cctttatgga gtatccacgc gttatgatac gtttcgctgt gattggtacg
    20521 aactggatca ctcgccagtt cgtcgaggcc gcccatgaga gcggtaaata caagttaacc
    20581 gccgtctatt cccgcagcct tgaacaggcc cagcacttcg ccaatgattt ttctgtcgag
    20641 catctgttta cgtcgctgga agcgatggca gaaagcgatg ccattgacgc ggtgtatatt
    20701 gccagcccaa attccctgca cttttcccag acacaacttt tccttagtca caaaattcat
    20761 gtgatttgcg agaagccact ggcgtcgaat caggcggaag tggatgccgc cattgcctgt
    20821 gcgcgggaaa atcaggtggt gctgtttgag gcatttaaaa cggcctacct gccgaacttt
    20881 catctgttac gccaggcgct gccgaaagtc ggcaaactgc gtaaagtctt tttcaactat
    20941 tgccagtatt cctcgcggta tcagcgttac ctggacggag agaatcccaa caccttcaat
    21001 ccggcattct ccaacggttc gattatggat atcggctttt actgcctggc gtcggcggtg
    21061 gcattattcg gtgaaccgaa aagcgtgcag gcaaccgcca gtttgctggc aagcggtgtg
    21121 gatgcccacg gcgtggtggt gatggattac ggtgatttca gcgttacgtt gcagcactca
    21181 aaagtgagcg attctgtcct ggcaagcgag attcagggcg aagcgggatc gctggtgatt
    21241 gaaaaactct ctgaatgcca gaaagtctgc tttgtaccgc gtggcagcca gatgcaggat
    21301 ctcacccagc cacagcatat taataccatg ctctacgaag cagagctgtt cgctaccctg
    21361 gtggatgagc atctggtgaa tcatccaggg ctggcggtca gtcgtatcac cgccaaactg
    21421 ctgactgaga tccgccgcca gactggggtg atttttccgg cagataacgt aaaactataa
    21481 ttgccaaagt aaaacagtgt aaaaggtatg taacagacca ttgactgact gaatggtctg
    21541 tcatactttg ttacctgcaa aggggagtaa cttcattgtc ggtcgatcgt cattacggtg
    21601 tgtgaaaaac cacatccggt caccgggcaa cccgaaagga atacgcagac gtattccttt
    21661 tttgttgtaa gtgagacctt gccggaaggc gaggtctatg cataaaaagc agcggctgac
    21721 gtcttccgac gttggccgtt tttttatgtg taaggaactt ctatgaatac tgtcggcacg
    21781 ccgttgctat ggggcggatt cgctgttgtt gtcaccatta tgctggctat cgacctgttg
    21841 ttgcaggggc gtcgtggggc acatgccatg accatgaaac aggctgcggc ctggtcgctg
    21901 gtctgggtga cgctgtcgtt actgtttaac gccgctttct ggtggtatct ggtgcaaacc
    21961 gaaggtcgcg ccgttgccga tccacaggca ctggcctttc tcacgggtta tctgattgag
    22021 aaatcgctgg cggtcgataa cgtctttgtc tggctgatgt tgttcagcta tttctctgtt
    22081 ccggcggcat tacaacgccg cgtgctggtg tatggcgtac tcggggcgat tgttctgcgt
    22141 accatcatga tcttcactgg tagctggctg atttcacagt tcgactggat cttgtatatc
    22201 ttcggtgcct tcctgctgtt taccggcgtg aagatggcgc tcgcccatga agatgaatca
    22261 ggcattggcg acaagccgct ggtgcgctgg ctgcgcggtc atttgcgcat gaccgacacc
    22321 atcgacaacg agcatttctt tgtgcgtaag aatggtttgt tgtatgccac gccgctgatg
    22381 ctggtgctga ttctggtgga gttgagcgac gtgattttcg ccgtggatag tattccggct
    22441 atcttcgccg tgaccaccga tccgtttatt gtgctgacct caaacctgtt tgcgatcctc
    22501 ggcctgcgtg cgatgtattt cctgctggca ggtgtggcag agcgtttctc gatgctcaaa
    22561 tatggtctgg cggtgattct ggtgtttatc ggtatcaaga tgctgattgt cgacttctac
    22621 catattccga tcgccgtctc gctgggcgtg gtgtttggca ttctggtgat gacgtttatt
    22681 atcaacgcct gggtgaatta tcggcatgat aagcagcggg ttggatgatt tttaatctgc
    22741 ctaagccgtg taccctgtca tccacatgag caccgttttc tccctctccc caaaaggggc
    22801 gaggggactg accgagtact tttttgacgt tgtcatcagt ctggaagccg cacgttgggc
    22861 tttattttca tgtcaaacaa atgtaaccat taagttgcga aatatgactt ctccttaaaa
    22921 tccagcatat ttcgcttccc gaagctgtaa ctttccttat actcgacctt gcaaacactt
    22981 tgttacatcc tgaaagatgc gtcgacagaa cgcaccaggg atgtgcgaca acacaatgaa
    23041 aggatcgaaa aatgactacg caacattcac cggggctatt ccggcgtctg gctcatggca
    23101 gcctggtaaa acaaatcctg gtcggcctta tactggggat tcttctggca tggatctcaa
    23161 aacccgcggc ggaagctgtt ggtctgttag gtactttgtt cgtcggcgca ctgaaagccg
    23221 ttgcccccat cctggtgttg atgctggtaa tggcatctat tgctaaccac cagcacgggc
    23281 agaaaaccaa tatccgccct attttgttcc tctatctgct gggcaccttc tctgctgctc
    23341 tggccgcagt aatcttcagt tttgccttcc cttctaccct gcacttgtcc agtagcgcgg
    23401 gtgatatttc gccgccgtca ggcattgtag aagtgatgcg cgggctggtt atgagcatgg
    23461 tttccaaccc cattgatgcg ctgctgaaag gtaactacat cgggatcctg gtgtgggcaa
    23521 ttggcctcgg tttcgcactg cgtcacggta acgaaaccac caaaaacctg gtcaacgata
    23581 tgtcgaatgc cgtcaccttt atggtgaaac tggtgattcg cttcgcaccg atcggtattt
    23641 ttggtctggt ttcttctacc ctggcaacca ccggtttctc cacgctgtgg ggctacgcgc
    23701 aactgctggt cgtgttggtt ggctgtatgt tactggtggc gctggtggtt aaccccttgc
    23761 tggtgtggtg gaaaattcgt cgtaacccgt tcccgctggt gctgctgtgc ctgcgcgaaa
    23821 gcggcgtgta tgccttcttc acccgcagct ctgcggcgaa cattccggtg aatatggcgc
    23881 tgtgtgaaaa gctgaatctg gatcgcgata cctattccgt ttctattccg ctgggagcca
    23941 ccatcaatat ggcgggcgca gcaatcacca ttaccgtgtt gacgctggct gcagttaata
    24001 cgctgggtat tccggttgat ctgcccacag cgctgctgtt gagcgtagtg gcttctctgt
    24061 gtgcctgtgg cgcatccggc gtggcggggg gatctctgtt gctgatccca ctggcctgta
    24121 atatgttcgg tatttcgaac gatatcgcca tgcaggtggt tgctgtcggc tttattatcg
    24181 gcgtattgca ggactcctgt gaaaccgcgc tgaactcgtc aactgacgtg ctgttcactg
    24241 cggcagcttg ccaggcggaa gacgatcgtc tggcaaatag cgccctgcgt aactaatact
    24301 tagccccttt cgtctacggc ggaaggggtt ttctccactt taaacggatc aattcccctt
    24361 ctctgcatac gccagaaacg aatgatattc aggccattca tcagcagaaa actgccttca
    24421 atcatcgtgc cgcctatcga ccccgcccag aagttgtgaa tcacccagca acacgttgaa
    24481 aaccacatta cgcagcgcat ggtcagccct ttacagcgga acagcgccca ggtactgaca
    24541 atcgtgccga ttaccggcaa tagttcaaca ggatgatgga acttcgcgag gccaattccg
    24601 ccagtcagca caataaaaat cgccattacc cataagctgc gcgtgcgtaa ggtaatcaat
    24661 gtacgaatgg cattaaggat ggcactggca ccggcaggat aggtgcccag aagaaaaaaa
    24721 tgtacgccaa taacggcgct atagaccgaa agttgctttt tgaagcgacg ttcgtcacga
    24781 ttgaaaaatg ttgtgatacc aatcagaaag gcgatgacac ccacgccctg ggccagccaa
    24841 tacgcggtca tgataaatcc ttagcaggta tggaaaagca aacggcgctt cacattatga
    24901 aacgccgttt tttattaaca actcatttcg actttatagc gttacgccgc ttttaaagat
    24961 cgccagttcg cggaagtcgt tacgctcgtt acaggtttgc ttaccgttgg caaactcaac
    25021 gatggtgtcg ataaattctt ccagcaactg cggcatcgct ttaccgtgga tcagctgacc
    25081 cgcgtcaaag tcgatccagt gttttttctt cgccgccagt tcactgttgg tggcgatttt
    25141 caccgtcggc acaaatccac catacggcgt gccacgacca gtactgaaca gcaccatatg
    25201 gcagcccgca cccgccaggg cgctggtcgc tacggcatcg ttacccggcg cacttaacaa
    25261 gttcagcccc ggcgttttca gacgctcgcc gtaacgcagc acgtcaacca cgacactgga
    25321 acccgctttc tgggtacagc caagcgattt atcttccagc gtggtgatac cgcctgcttt
    25381 gttccccggt gatgggtttt cgtagatcgg ctggtcatgg gcaataaagt actgcttgaa
    25441 gtcattgacc atggtgacca gtttttcaaa cgttgcttcg tcgcggcaat ggtccatcag
    25501 caactgctct gcgccaaaca tctccggcac ttcggtcagt acggtagtac cgccgttagc
    25561 aatcacgtag tcagagaaac gccccagcat cgggttagca gtaataccag aaagaccgtc
    25621 agaaccaccg cactccagac caaacttcag ttcgctgagt ttgcccggct cgcgtttatc
    25681 gttgcgcatc acgctataca gctgatgcaa atgcgcgatc ccggcctcga tttcatcatc
    25741 ctgctgttgg cagatcatga aatgaacgcg ttcaggatcg atatcgccca acgtttcacg
    25801 gaatgcggca acctggttat tttcgcaacc cagaccaatc accagcactg cgcccgcgtt
    25861 cgggtggcgc accatgtttt gcagcatggt gcgggtattg atgtgatcgt cgcccagttg
    25921 tgagcagccg taggtgtggc tgaagaggaa cacgccgtcg gtaccttcag cgttgttggt
    25981 ctctttcagg aaacgatttt ggatctgccg cgcgatgccg ttgacacagc ccacggttgg
    26041 caggatccac agctcattac gcaccccgac atcaccgtta gcgcgacgat agatctgcac
    26101 ttcacgatct gccgcttgcg caggcagatc ctgaaaatca ggttgatagc gatactgatc
    26161 cagatcgctc agattcgtgc gcgtattgtg ggcgtgaacg tgttcccccg ccgcaatatc
    26221 cgccaatgca taaccaatcg gcaggccata tttaatgacg ttggcccctt ttgcgatatc
    26281 cgttaacgca aatttatgtc cacgagcaac atcctggcgc agcgtaacag tctggttatc
    26341 gacactgact tctgtgcctt cagccaaatc cgctaaagca accgcgacgt tatccagcgc
    26401 atggatcttg atgtattgca tatcaacccc agaccttagt tcagttcaat ggcgaagtag
    26461 tcacgcgcat tgttaaagca aatatttttc accatctcgc ccagcaggtt gatgtccgcc
    26521 ggtgcttcgc ctgcttccac ccagcgaccg atcatctggc acagaatgcg gcggaagtat
    26581 tcgtgacggg tgtatgacag gaagctacgg ctgtcagtca gcatgccgac aaagcggctc
    26641 agcagaccga gctgcgccag ttgggtcatc tgacgttcca taccgtcttt ctggtcgtta
    26701 aaccaccagc cggaaccgaa ctgcattttg cccggcatac cttcgccctg gaagttaccg
    26761 atcatggtgc ccagcacttc gttatcgcgc gggttcaggc agtagagaat ggttttcggc
    26821 agcaggtttt cttcgttctg cttgctcagc agcttagata gctcttccgc catcggacgg
    26881 tcgttgatgg agtcaaagcc gacatccggc cccagcagtt tgaactgacg caggttgtta
    26941 ttacgcagtg cgccaatgtg gtactgctgt acccatccgc gacgtgcata ttcggcacca
    27001 aggaacacca gcaccgcagt tttgaactgt gctacttcgt gctcgctcag ggtttcgcct
    27061 gccagacggc gcgcgaggat gctgtccagt tccgcttcgt tcgcttcagc aaacatcacc
    27121 acatccagcg cgtggtcaga cactttacag ccgtgagcgg cgaagtgatc cagacgttta
    27181 gtcagggcag tttgcaggtc agcaaagcgg cgaatgtcgg tatcagaaac ttcgcccagc
    27241 ttcgccatgt agtcgttaaa ggtcgcctgt tcaatgttaa aggctttgtc cggacgccag
    27301 ctcggcagca ctttaatggt gaaagagccg tctttggcga tctctgcgtg atgctccaga
    27361 gaatcgatcg ggtcatcggt ggtgccgacc attttcacgt tcatctgctg catgatgccg
    27421 cgcgcggaga agttatcctg cgccagcagt tcgttacatt cgttccagat ttcatcggca
    27481 gttgacggag aaagcaattt gccagtgata ccaaacggac gacgcagttc gaggtgcgtc
    27541 cagtggtata acgggttgcc gatagtgtgc ggaacagtcg ccgcccaggc gtcaaatttt
    27601 tcacggtcag acgcatcacc ggtgcacaga cgctcggcca caccgttggt acgcatagcg
    27661 cgccatttgt agtgatcgcc cttcaaccag atgtcataca ggtttttaaa acgatagtct
    27721 tccgcaatct gctgcggcgg caaatggcaa tggtaatcga aaatcggctg gtcttttgcg
    27781 tagtcgtgat acagacggcg ggcaaattca gtatctaaca ggaaatcttc agtcataaac
    27841 ggagtcattt tcgtcttcct ctcaacgagt gagctagctt gcttatggtg cgatgctgac
    27901 aaagttatca caccaatttc cagagtccga agatattttc gtgagttaga tcaataaacg
    27961 tagttaaaaa aattactctc aaagtggtaa atctcgctgc aggccgcgcc agtactggcc
    28021 tcgtcgtcgt caggtaatgt ccctacaaat attcgcacat ttgtgatggc tctcaccttt
    28081 taaagttgta tgacaagtta tctttctgcc gtcgcaaatc ataagtcgac ggaatgcaaa
    28141 ttgccgattc attcatttgt tagatgaatc gggttaaccg gtacggaagc cgaattagca
    28201 cgaaactttc atggcaacgt tcggggcgtg ccggtttttt ttcggttacc cggtcgtaac
    28261 taacatcttc agcctctggc gggatgatgg ccgcgcttcc tgcggatata acaaaacgat
    28321 gaggttttac atgcgtaaaa ttaaagggtt acgttggtat atgatcgcac tggtgacgct
    28381 cggcaccgtg cttggttacc tgacgcgtaa cactgtggcg gcagctgcgc caactctgat
    28441 ggaagagtta aacatctcca cccaacagta ttcctatatc atcgcagcgt attctgctgc
    28501 ttatacggtc atgcaaccgg tagcgggtta tgtactggat gtgctgggta cgaaaatcgg
    28561 ttatgcaatg tttgctgtac tgtgggccgt gttctgtggt gcaaccgcgc tggcaggtag
    28621 ttggggtggc ctggcggttg ctcgtggtgc ggtcggtgcc gcggaagccg cgatgattcc
    28681 ggcgggtctg aaagccagct ccgaatggtt cccggcaaaa gagcgttcca tcgcggtagg
    28741 ttactttaac gtaggttctt cgattggtgc gatgattgcg ccgccgctgg tggtatgggc
    28801 aatcgtgatg cacagctggc agatggcatt tatcatctcc ggtgcgttga gctttatctg
    28861 ggcgatggca tggctgattt tctacaagca tccgcgcgac cagaaacatc tgaccgatga
    28921 agaacgcgac tacattatta atggtcagga agcccagcac caggttgaca cagcgaagaa
    28981 aatgtccgtt ggtcagatcc tgcgtaaccg tcagttctgg ggtatcgcgc tgccgcgctt
    29041 cctggcagaa ccggcatggg gtacttttaa cgcgtggatc ccgctgttca tgtttaaagt
    29101 ttacggcttt aacctgaaag agatcgcgat gtttgcctgg atgccgatgc tgtttgctga
    29161 cctcggttgt atcctcggtg gttacctgcc accactgttc cagcgttggt ttggtgtgaa
    29221 cctgatcgtt tcccgtaaga tggtcgtaac gctgggtgcg gtgctgatga ttggcccggg
    29281 tatgatcggt ctgttcacca acccgtatgt cgcgattatg ctgctgtgta tcggtggttt
    29341 tgctcaccag gcactgtctg gcgcactgat tacgctctcg tctgacgtgt tcggtcgtaa
    29401 cgaagtggcg acggcgaacg gtttaaccgg gatgtccgca tggctggcaa gtacgctgtt
    29461 tgcactggta gtcggtgcac tggctgacac catcggcttc agcccgctgt tcgcagttct
    29521 ggcagtgttc gacctgttag gtgcgctggt tatctggacc gtgttgcaga acaaaccagc
    29581 gattgaggtg gcgcaggaat cacataacga tcccgcaccg caacattaag gcttcgtgta
    29641 agttttagtt tcccttcaaa gccgccttct caggcggctt tttcatcact gcgagtagag
    29701 ctaaactcgc aaaagtggta taacaaatat agtctgccgt atcatgcctg gagcgcatat
    29761 ggaaatcact gaaccacgcc gtttgtatca acaacttgcc gctgatctga aagagcgcat
    29821 cgaacagggc gtctatctgg tgggtgataa actgcctgcc gaacgcttta ttgccgatga
    29881 aaaaaacgtc agccgcaccg tggttcgtga agccatcatc atgctggaag ttgaaggcta
    29941 tgtcgaagtg cgtaaaggtt caggtattca tgtggtttcc aaccagccgc gccatcagca
    30001 ggcggctgac aataatatgg aattcgccaa ttacggtccg tttgagttgc tccaggctcg
    30061 ccagctcatc gaaagtaata ttgccgagtt cgcggcaact caggtcacaa aacaggacat
    30121 catgaaattg atggccattc aggagcaggc acgcggcgaa caatgcttcc gtgattccga
    30181 gtgggatttg cagttccata ttcaggtagc cctggcgacg cagaactccg ccctggcggc
    30241 tatcgttgaa aaaatgtgga cccagcgtag tcataacccg tactggaaaa aactgcacga
    30301 acacattgat gcccgtaccg tcgataactg gtgtgatgac cacgatcaaa tcctcaaggc
    30361 gctgattcgc aaagatcctc atgctgctaa gctggcaatg tggcagcacc tggaaaacac
    30421 caagatcatg ttatttaacg aaaccagcga cgatttcgag ttcaatgccg accgctatct
    30481 gttcgccgaa aacccggtgg tgcatctcga tacagccacc agcggcagta aatgaaattc
    30541 ctgtccgaca ggcgctacag tgcgcctgtt tgtctcgtcg gtaagcgaaa agtataaagt
    30601 gtcagcctgt gtaaatcctc tcgcctccct cccctgcatt cagcaaaatc agactccatg
    30661 gacatgtaat tttgataacg aacaacgttg acctttgtta caattagatt caatttgaat
    30721 ttatgctttt gaatgctttc ttatctcacg atttaacagg gaatagttca ggctgtgttg
    30781 atgtatcaaa cccgcagaac ataccaagac agcaataaca ttgcggtagt gcatcattta
    30841 aaaccagcgt ggcgttaacc gattcaccag gaataatgaa tggaactttt gacccaattg
    30901 ctgcaagccc tgtgggcgca ggattttgaa accctggcca atccgtcgat gattggcatg
    30961 ttgtattttg tcttgtttgt cattttgttc cttgaaaacg gcttgcttcc ggcggccttt
    31021 ttaccgggcg acagtttact ggtactggtc ggcgtattga ttgcgaaagg cgcgatgggc
    31081 tatccgcaaa cgattctgct gctgaccgtt gccgccagcc tcggttgctg ggtcagctat
    31141 attcaggggc gatggctggg caatacccgc accgtacaaa actggctatc tcatttaccc
    31201 gcgcattatc atcaacgcgc acaccatctt tttcataaac acggtttatc ggcgctgtta
    31261 attggtcgct ttattgcgtt tgtcagaaca ctgctgccga cgattgccgg gttatcaggg
    31321 ctgaataacg cgcgctttca gttcttcaac tggatgagtg gtctgctgtg ggtgttgatc
    31381 ctgacaactc tgggttacat gctcggcaaa acaccggtat ttttaaagtt cgaggaccag
    31441 ctgatgtcat gcctgatgct gctcccggtg gtgctgctgg tgtttggcct ggcaggttct
    31501 ctggtcgtgt tatggaaaaa gaaatatgga aatcgggggt aagggatgca aatacctcgc
    31561 atgtcacttc gccagctagc ctggtccggc gctgttttac ttctggtcag cacactattg
    31621 ctggcctggt ccgcggttcg ccagcaagag tctacgctgg cgattcgtgc cgttcatcaa
    31681 gggacaacga tgccagacgg tttttcaatc tggcatcacc ttgacgctca cggcattcct
    31741 ttcaaaagta tcacccccaa aaacgacact ctgttaatta cctttgactc cagcgaccag
    31801 agcgccgccg caaaagcggt cctcgacaga acattgcccc atggctacat cattgcgcag
    31861 caggacaata acagtcaggc tatgcagtgg ctgacccggt tgcgggataa ctctcatcgc
    31921 ttcggataac ttcctgttat ccgaaacaga tcactcactt tggtgatttc accgtaactg
    31981 tctatgatta atgaggcggt ggttaacacg accgcttcgt tgtctggaca atcgttcctt
    32041 tgtaataggt ccgaatcaca atggaaggtt caagaatgaa ataccgcatc gctttagctg
    32101 tttctctctt tgctcttagt gccggtagtt atgccactac cctgtgtcag gaaaaggagc
    32161 aaaatatcct taaggagatc agctatgccg aaaaacacca aaaccagaat cgtattgacg
    32221 gtctgaataa agccctgagt gaagtccggg ccaactgttc agatagccaa ctgcgtgccg
    32281 atcatcagaa gaaaatcgca aagcagaaag atgaggtggc ggaacgccag caagatttag
    32341 ccgaggcgaa gcaaaaaggc gatgcagata agattgccaa acgcgaacgg aaactggcag
    32401 aagcgcagga agagctgaaa aagctggaag cgcgcgacta ctaactcaca atagtcacta
    32461 cttactcacc tggagaaaac tatgtcgaaa gaacacacta cggaacatct gcgtgctgag
    32521 ttgaaatccc tttccgatac gctggaagag gtgcttagct catctggcga gaagtcaaaa
    32581 gaagagttga gtaagattcg tagcaaagcg gagcaggcac tgaaacagag ccgttatcgc
    32641 ctgggtgaaa ccggtgatgc cattgccaaa caaacccgtg tcgcggcggc gcgtgccgat
    32701 gagtatgtgc gtgaaaatcc gtggacgggc gtgggcattg gcgcagcaat cggtgtagtg
    32761 ctcggcgttc tgctgtcgcg tcgttaatta tggcggacac tcatcacgcg caagggcccg
    32821 gtaaaagcgt tctgggcatc gggcagcgaa ttgtttccat catggttgaa atggtggaga
    32881 cacgtctgcg gctggcggtg gtggagctgg aagaggaaaa agcgaatctc tttcaacttt
    32941 tactgatgct gggcctgacg atgcttttcg ctgcatttgg tcttatgagc ctgatggtgc
    33001 taattatctg ggcggttgat ccgcaatatc gcctgaatgc gatgattgcc accaccgtgg
    33061 tgttgctgct actggcactg attggcggca tctggacgtt acgtaaatcg cgtaagtcta
    33121 cgttgctgcg ccacacgcgc catgagctgg caaacgatcg gcagctgctc gaggaggagt
    33181 cccgtgagca gtaaagtcga acgtgaacga cgtaaggcgc aactgcttag ccagatccag
    33241 caacaacggc tggatctttc cgccactcgt cgtgaatggc tggaggcaac aggcgcttac
    33301 gatcgtcgct ggaatatgct gttgagtctg cgctcctggg cgctggttgg cagtagcgtg
    33361 atggctatct ggacgattcg ccatcctaat atgctggtcc gctgggccag acgcggtttt
    33421 ggtgtatgga gcgcctggcg tctggtgaaa acaaccctca agcaacaaca gcttcgcggt
    33481 taacttcctc tctggccgga gaaattccgg ccttattcct caaatttttt gaaaatattt
    33541 gacagttttc cttgctaaca atcacgcttc gccacgttta tgattctctc catcgacagc
    33601 aacgacgcta atagcgcgcc cttgcacaaa aaaacaatca gcagcctgag cggcgcagtg
    33661 gagagtatga tgaaaaaatt agaagatgtt ggtgtactgg tagcgcgtat tttaatgccg
    33721 attctgttta ttaccgcagg ctggggaaaa attactggct acgcgggtac ccaacaatat
    33781 atggaagcaa tgggcgtccc cggctttatg ctgccgctgg tgattctgct tgagtttggt
    33841 ggtggtctgg caatcctgtt cggtttcctg acacgtacca cagccctgtt tactgcgggc
    33901 tttacgctgc tgacggcatt tttatttcac agcaattttg cagaaggcat gaactcgctg
    33961 atgtttatga aaaacctgac tatttctggc ggattcctgc tgctggcaat taccggtcca
    34021 ggcgcattca gcatcgaccg cctgctgaat aaaaagtggt aagcacgcgc tatacttaac
    34081 gataaaaaac gagggggaag ctcctcgttt ttgctattgg aggatagaaa aatgggtcaa
    34141 ctgattgacg gcgtctggca tgacacctgg tacgatacca aatccaccgg cggtaaattt
    34201 caacgttcag cttccgcatt tcgtaactgg ctcactgccg atggcgcgcc aggccccact
    34261 ggcaaaggcg gttttgccgc agagaaagat cgttatcatc tctatgtttc actcgcctgc
    34321 ccgtgggcac accgcacgct gatcatgcgt aagctcaaag gactggaacc gtttatttcc
    34381 gtttccgtag tgaacccgct gatgctggaa aacggctgga cctttgatga cagttttccg
    34441 ggagcaagcg gcgacacgct ctatcaacat gaatttctgt atcagcttta tctccacgcc
    34501 gatccacact acagcggacg agttactgtt cccgtgctgt gggacaaaaa aaaccacacc
    34561 atcgtcagca acgaatcagc agaaatcata cgcatgttca ataccgcgtt tgatgcgctg
    34621 ggtgcgaaag ctggagatta ctacccacca gccctgcaac cgaaaattga cgaacttaac
    34681 ggctggattt acgacaccat taacaatggc gtgtataaag ccggttttgc caccagccag
    34741 caagcctacg acgaggcggt ggcgaaagtg tttgaatcgc tggcgcgact ggaacagatt
    34801 ttaggtcagc accgttacct gaccggcaac cagctaaccg aagccgatat tcgcctgtgg
    34861 accacgctgg tgcgttttga tccagtgtat gtgacccact tcaagtgtga taagcaccgc
    34921 atcagcgatt acctgaatct gtatggcttc ctgcgcgata tctaccagat gccgggaatt
    34981 gccgaaacag tcaatttcga tcacatccgt aatcattact tccgcagcca taagaccatc
    35041 aaccctacgg ggattatttc aattggtccg tggcaggatc tcgatgaacc gcatggacga
    35101 gatgttcgct tcggttaaaa aaaggcacct tacgaggtgc ctctgataat tagctaagta
    35161 cgtgttgttc atgtcggatg cggcgtaaac gccttatcaa acctacaaaa catttatatt
    35221 caatatgttg caatgaccgc gcaggccaga taagcgtagc gcatctggca attttgcgtt
    35281 tgcccttatc cttcacagcg ccttattaat tcatcgcgat aatatttact gccatttcat
    35341 tcacgtctat tcttaatttg ctgctttaaa aacaagtgat tgagcaaaat tgaggcaaaa
    35401 atggactggt atctgaaagt actaaaaaat tatgtcggtt tccggggtcg tgcgcggcgc
    35461 aaagagtact ggatgtttat tctggtcaac atcatcttta cgttcgtgct ggggctactg
    35521 gataaaatgt taggctggca acgtgccggt ggcgaaggca tcctgacgac aatctacggt
    35581 attctggtgt ttttaccatg gtgggcagtt cagttccgcc gcctgcacga caccgaccgc
    35641 tcggcgtggt gggcactgct attcttaatc ccgtttatcg gctggcttat tatcatcgtc
    35701 tttaactgcc aggcgggtac gccaggcgaa aaccgctttg gaccagatcc gaaactggaa
    35761 caagaataat aattaagcac cttgtaaaag gtgcttaatc gattattttc cgctaaaaag
    35821 tttgggaatt tcccgcagac accaggattt cgcctccccc atactgtcac gacgccaggc
    35881 cataataata tcgatctcgc tggtcgattc cgggctgacg acacgcaacc gcccttccgc
    35941 aatatctttt tcgaccatcg gatacggcat cgtcgccacg ccaagccccg ccagtaatgc
    36001 ctgacgttta tcttcaatcg tgctcaccgt taagcgcggc tgtttgtcca gcaactgtac
    36061 ggtcaacacc gggcgctcac gagcggtatc cgccaccgca attccacgat atttcacgcg
    36121 cgtcacttca gataacggtt ccggctcctg atgaatcggg tgatccggcg cggcaacata
    36181 gacgttcatt aaggtataga gtttgcgcga gttgatctcc gacgaggaac gaaaatgcat
    36241 atccggcgcg ataacgatat ccgcccgccc ctgctccagc cgttcccacg cccccgccag
    36301 cacttcggtg ataattgcca gttgggtatt ggcttttgcc gccagtttgt cgattaacgg
    36361 gaaaaaggca ggtgtcggta ccagcgcctc ggtcacaatg gtgagatgcg tttcccaacc
    36421 gcgcgcgagg gcttccgcat cggtagtcag tttatctgcg gcttccagca aaacgcgccc
    36481 tcgctccagc aacatcctcc cgacattggt gaatttggtg cgatggcccg agcggtcaaa
    36541 cagcaccaca tccagctctt cttccagttt ttgcatggtg tagctaagtg cggaaggcac
    36601 gcgtcccagc tcatccgccg ccgccgcaaa actgccccgg cgatcgatcg catccataac
    36661 ccgtagtgct tccagcgtta atgccctttc tttggccatt tcgttctcat tcaggaaatt
    36721 tgaacatacc gggcagaata tctggctaac aatgtagcgt ccagcccctt accataaaag
    36781 gaagtaaaga gaggtcaaga attatgatta ctacccgaac tgccaggcag tgtggacaag
    36841 cagactacgg atggttgcag gcccggtata ctttttcctt tggacactac ttcgacccga
    36901 aattgttagg ctatgcctct ctgcgcgtgc ttaaccagga agtgctggcc ccaggtgccg
    36961 cctttcagcc acgaacctat cccaaagtcg atattttaaa tgtgattctg gatggagaag
    37021 ctgagtatcg cgacagcgaa ggcaatcatg ttcaggccag cactggtgag gtgttgctgc
    37081 tctctaccca gccgggtgtc agctatagcg aacacaatct cagcaaagac aaaccgttaa
    37141 cgcgaatgca gctttggctg gatgcctgcc cgcagcgaga gaatccgctg attcaaaagc
    37201 tggcgcttaa tatgagcaag cagcaattaa tcgcctcgcc agaaggtggg atgggaagcc
    37261 tgcaattgcg ccagcaagtg tggctgcacc atatcgtgct cgacaaaggc gaaagtgcga
    37321 atttccagtt gcatgggcca cgcgcgtatt tgcaatcgat tcacgggaaa tttcatgcgc
    37381 ttacgcatca tgaagagaaa gcggcgctaa cctgcggtga tggggcgttt attcgtgacg
    37441 aggctaacat tacgctggtt gccgattccc cactgcgcgc tttgctgata gatttgcctg
    37501 tctagttgtt tttacaggga gatgatgatg agtaaaaaat cggccaaaaa gcgccagcca
    37561 gtgaagcccg tggtggcgaa agaacctgct cgtaccgcca aaaattttgg ctatgaagag
    37621 atgttgagcg aactggaagc catcgtcgcg gatgctgaaa cgcgtttagc cgaggatgaa
    37681 gctaccgcgt aaagacaggt tgccggatgc ggcgcaaacg ccttatccgg cacaataccc
    37741 aaaaccgggc gtttatctgg ccttgctcgc cataatctcg ataatctgcc gatccgtttg
    37801 ctacatcgaa tggcttgcta acgcacacag gttggcaatc gactgctcaa catcatgcgc
    37861 cacaatccct tcattgccgg tcacggcggt atcatccagc gccattaaca ccgctttcca
    37921 cgcagccgaa gcactggtcg aaaccttcat cgcgcagctg ttcgatgcac catcgcaaat
    37981 catgccgctg acatcgccga tcatactgct gatcgccatc gagatggttt cataacgccc
    38041 atccaccagc catgccatcc cggcagcggc ccccattgct gcggtcgttg cggcacacag
    38101 cgcagacaaa cgcggtaact ggttatggat gtaaatcgcg ctcaaatgcg aaagcatcag
    38161 cgcacgcgcc agccgttcat catccgctcc gaagtgttca gctaccacca ccacgggcat
    38221 tgttgcggtg atcccctggt tacccgagcc ggagttactc attgccggaa gcgtagcgcc
    38281 gcccatacgc gcatcggatg ccgcgctggt acgaatcaca atggatgaag agagatcttt
    38341 cgccagcaaa ccgcgcgcgc actgtttttc cagcgtcgca ccaatatgca gcccccagtt
    38401 accgctcaaa ccttcctgcg ataacgcaca atttaacttc gcagaatcga gaataaagcg
    38461 gatcgccgca aacgggactt cattgacgaa cttcaggatc tcagccagcg tcgtcctgga
    38521 aagcaccgtc agcggcgact cttgctcgcc ctctgccaca cacgcctgct gggtaaacac
    38581 cacaccattg tgcgtctcaa tatgcacaat gttggtatgc ccgccgacga tggtgacaca
    38641 cgcccatttc tcaccgttcc agactttggc gcgtgagaag aggatttcat cgcaaggttc
    38701 ctggatctta actgagactt tccccgccgc cagcagtgct ttggcatcgg aaattgcctg
    38761 cgcagttgcg tctttcagca cttccagccc ggcgttagca tttccaccta acgctcccag
    38821 cgccgccgca attggcagcc ccaccattcc tgtaccggga acggtgacac ccagaccgtt
    38881 cttcatcaga tttggcgaaa cccaggcttc tacacgttca accggacctt ccagttcagc
    38941 cgcagcaacc gccgccgcca gcgccagtga aatcggttca gtacacccca gcgccggttt
    39001 tacttcctcc tgaacggcga ggatgtaacg ctgccataac ggatttaaag tcgaatcaaa
    39061 catattaaaa accttaaaat ttcaggtaaa tcaagaaaat gccaggaacg gagaaacaca
    39121 aagcaacaaa ccagtgacga taatcaggta caaagacatc cctttgtatt tgtgcaatgc
    39181 cggtactttg taaaccagcc acgccgggat caggcaccct accatgccga aaatcgggct
    39241 acagatagag gtgaagctca acaccggggc gttcagtacg atggcgctcc aggccagcaa
    39301 aatggcgaaa atcatgatgc cgcgctgaac gagattttcg ttaatcttct cggcaggtat
    39361 cttgcgacgc aggatgttca ttacgatccc ttgcgttgct tcgcgaaagc ctaaatagac
    39421 gccaaagaat gcagtcatta cagcaaagat attgagaatg acgctgacca ctttcaccca
    39481 cgctgcgccg tcaccgctaa taaactgtgc ggcaatcgcc agcgcggaaa tattctgctc
    39541 gtaggctttt accgcttcgt catgtcccat cgccagcgtg aacgacacgg cgtagaaaaa
    39601 gacggtgaca aacaaaatgc caaacgcgat attcattgcc cgcaatgctt tatgccgcgc
    39661 cacttcaatt gatttttccc gcgagcgata agagatcacc atcgggctta acgtctggat
    39721 aaatagaatc gacgtcaggg taaacggcag cgtaataatg gcgtttttca tcagcagccc
    39781 cagcggcggt agcgaaccga cgttatacag atgccacatt cccaccatcg acacgcccag
    39841 cgccgcgacc accagcagct tggtcagcac catgccggtc gaaattttga ataacaattt
    39901 ctcgccgcgt gaggagatcg ccaccagaat gcaaatcagt accagaccat aaaagggact
    39961 gtctgaca
//
LOCUS       DAFGPF010000034        39088 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFGPF010000034 DAFGPF010000000
VERSION     DAFGPF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39088
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.034"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(37..633)
                     /locus_tag="LSX49_002004"
     CDS             complement(37..633)
                     /locus_tag="LSX49_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL7168421.1"
                     /translation="MNNTDLIHLIKHFMRNEHKAVEEVIDSPLSEVANLIKVLQSCQG
                     KVVFIGVGKSGIIARKLAATFASTGTPSFFVHGTEAVHGDLGMVAKDDVVILISNSGE
                     TAEILATLPSLKKMGNYLISFTRSHHSSLAISCDLSVEIPVKSEADNLGLAPSCSSTV
                     VLVVGDAVALALSELKKFTRADFGLYHPGGALGIKANS"
     gene            complement(636..1811)
                     /locus_tag="LSX49_002005"
     CDS             complement(636..1811)
                     /locus_tag="LSX49_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000382418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBL7168422.1"
                     /translation="MDVFNTPVSRKGTYCTQWDFCEDRFGVKDVLPFSISDMDLPIPD
                     AITRALKKRLEHPILGYSRWQHGEYLNAIVNWYYQQYQTDIKPEWITYSPSVMYSIAK
                     AIELLTSHGDNILVFTPVYNAFFDVIKHSERNILTASLIIKNEGSYAINWQDFDLKIK
                     SAKMVLLCNPHNPTGTVWSEEELHKIAASCTRHNVWLCSDEIHSDFVFNRSFTSALKI
                     KKEKVVVFNSISKTFNVPALTGSYMISTDDNFNHKFRTISRYRDFVNSPSVLNIIATI
                     IGYNECEGWLKSLKAHIASNIQFTQQYLNENIPELIVRPADGCYFSWIDCSAIGYPFD
                     EFYSRLIHEGKVGIMAGHVYGTEGEGYLRLNLACSREKLYMGLTRLVSVIKNINQGE"
     gene            complement(1811..3391)
                     /locus_tag="LSX49_002006"
     CDS             complement(1811..3391)
                     /locus_tag="LSX49_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL7168423.1"
                     /translation="MKQKKAWSFFQSLGKAFMYPIALLSVCGMMLGLGSGLASDDMAK
                     LIPFLAIPIIKTILDFIVSLGLFAFVNLPVLFAIAIPLGLLKDKEDKAYGAFSGLIGF
                     MAMHLGTNFYLKQHDLLVVADQMSTHGQTIILGIQSYNTSVLGGIVAGLLVASMYKKI
                     VNLRIPESLGFYSGPRLVPIITLIVMSGFGLIIPFIWPPFFNLFMLIGHWISTSGPVG
                     YFFYAVAERVTIPFGLNHLVTSVFRFTPIGGSAVIGGEEYYGTLNMFMAYVKENAVIP
                     LDLAGKMEQGKLMIQYGLAGAALAMYRTAHAQNRKAIKALLISGVLTVIIGGVSEPIE
                     FLFLFVSPLLFVFHAFMNGFANMVLPYMGVKMGFTGDLIQFISFGVLRGTRTGWPIAV
                     CVEVAYFFIYYFVFRWTILKFNLMTVGREESSPVTLNAHEDTAIADIPTPDKSELQAA
                     EQMVKALGGKENIKSLDNCVTRLRLTIADMGLIDEVAIKIAGGIAVVKLDQNTLQVII
                     GTKVIALRRDMDNYMGIY"
     gene            complement(3423..4247)
                     /locus_tag="LSX49_002007"
     CDS             complement(3423..4247)
                     /locus_tag="LSX49_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL7168424.1"
                     /translation="MIIEKVMNNNCVQASMNGQEVIISGPGVGYNKKYGMSVPEHPAN
                     RIFYVRNEQKNKLYKLIEHVDIEYVFVAEKIVQYAEKNLEKNLNPSLLLILADHISNA
                     ISRVASGIQINNVFLDEIKALYKAEYAISRDALTIINEQFSVQLPDDEIGFIALHILN
                     NYENSVDYESVRIIELSQIITGLIEVVYNRKVDRSSFNYSRFMMHLKYFSSRVLCNEE
                     IKQKDIGDIYEQFLEKDILLQRAIHEIERYLYATFKYELILEEKLYLSIRTKVLMD"
     gene            complement(4505..5758)
                     /gene="amiC"
                     /locus_tag="LSX49_002008"
     CDS             complement(4505..5758)
                     /gene="amiC"
                     /locus_tag="LSX49_002008"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HBL7168425.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATLARRG"
     gene            5990..7321
                     /gene="argA"
                     /locus_tag="LSX49_002009"
     CDS             5990..7321
                     /gene="argA"
                     /locus_tag="LSX49_002009"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HBL7168426.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQTRVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(7403..9229)
                     /gene="recD"
                     /locus_tag="LSX49_002010"
     CDS             complement(7403..9229)
                     /gene="recD"
                     /locus_tag="LSX49_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HBL7168427.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTAEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERAGQLSRLTG
                     SHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTD
                     IEKRLLQSGEDYIAMLEEVLAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRG"
     gene            complement(9229..12771)
                     /gene="recB"
                     /locus_tag="LSX49_002011"
     CDS             complement(9229..12771)
                     /gene="recB"
                     /locus_tag="LSX49_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HBL7168428.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYKRLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIDAVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIEKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGEMQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDAVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDVAGLRTC
                     IEALCDDDIAWQTAQIGDNQPWQVNDALTAELNARTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVVSVVEVPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VQEKLELGGFEPQWEPVLTEWITAVLLAPLNETGISLSQLSDRDKQVEMEFYLPISEP
                     LIASQLDALIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYERHFGGVIYLFLRGV
                     DKEHPQQGIYATRPNAGLIDLMDEMFAGMTLEEA"
     gene            complement(12764..15652)
                     /gene="ptrA"
                     /locus_tag="LSX49_002012"
     CDS             complement(12764..15652)
                     /gene="ptrA"
                     /locus_tag="LSX49_002012"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HBL7168429.1"
                     /translation="MPRSIWFKALLLFVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAANIALSLPELNPYIP
                     DDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEAQAITLARHVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPEEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKIADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(15828..19196)
                     /gene="recC"
                     /locus_tag="LSX49_002013"
     CDS             complement(15828..19196)
                     /gene="recC"
                     /locus_tag="LSX49_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HBL7168430.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLPQL
                     LEREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTDELGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVTPDNL
                     LHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(19209..19532)
                     /locus_tag="LSX49_002014"
     CDS             complement(19209..19532)
                     /locus_tag="LSX49_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBL7168431.1"
                     /translation="MSASLRNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLASR
                     NQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(19517..19924)
                     /locus_tag="LSX49_002015"
     CDS             complement(19517..19924)
                     /locus_tag="LSX49_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311708.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HBL7168432.1"
                     /translation="MNREKGVSSLALVLMLLILGSLLLQGMSQQDRSFASRVSMESQS
                     LRRQAIVQSALEWGKMHSWQTLPAVQCLLYAATGARVCLRLLADNEALLIAGYEGVSL
                     WRTGEVIDGNIVFSPRGWSDFCPLKERALCQLP"
     gene            complement(19921..20484)
                     /locus_tag="LSX49_002016"
     CDS             complement(19921..20484)
                     /locus_tag="LSX49_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HBL7168433.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTNTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGSCTGEGLEIVGQGDCVIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGATSCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
                     TVNMHAASKADPQTVVDASYSVTGSNL"
     gene            complement(20475..20945)
                     /locus_tag="LSX49_002017"
     CDS             complement(20475..20945)
                     /locus_tag="LSX49_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HBL7168434.1"
                     /translation="MKKQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISLIREGTLWCLVSSVAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(21130..21924)
                     /gene="thyA"
                     /locus_tag="LSX49_002018"
     CDS             complement(21130..21924)
                     /gene="thyA"
                     /locus_tag="LSX49_002018"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL7168435.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(21931..22806)
                     /gene="lgt"
                     /locus_tag="LSX49_002019"
     CDS             complement(21931..22806)
                     /gene="lgt"
                     /locus_tag="LSX49_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL7168436.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(22957..25203)
                     /gene="ptsP"
                     /locus_tag="LSX49_002020"
     CDS             complement(22957..25203)
                     /gene="ptsP"
                     /locus_tag="LSX49_002020"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL7168437.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRRIDFAEAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(25216..25746)
                     /gene="rppH"
                     /locus_tag="LSX49_002021"
     CDS             complement(25216..25746)
                     /gene="rppH"
                     /locus_tag="LSX49_002021"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HBL7168438.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            26431..27120
                     /gene="mutH"
                     /locus_tag="LSX49_002022"
     CDS             26431..27120
                     /gene="mutH"
                     /locus_tag="LSX49_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HBL7168439.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAKRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDMIVLGQIERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLARHFLIQ"
     gene            27189..27902
                     /locus_tag="LSX49_002023"
     CDS             27189..27902
                     /locus_tag="LSX49_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HBL7168440.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            28040..28258
                     /gene="ygdR"
                     /locus_tag="LSX49_002024"
     CDS             28040..28258
                     /gene="ygdR"
                     /locus_tag="LSX49_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HBL7168441.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            28366..29406
                     /locus_tag="LSX49_002025"
     CDS             28366..29406
                     /locus_tag="LSX49_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HBL7168442.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHSLDPAQMALAFVRRQPFVASTLLGATTMEQLKTNVESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(29438..30631)
                     /gene="lplT"
                     /locus_tag="LSX49_002026"
     CDS             complement(29438..30631)
                     /gene="lplT"
                     /locus_tag="LSX49_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HBL7168443.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLIALAACALAYGGAVIANIYIPKLAAARPGQSWNLISMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(30624..32783)
                     /gene="aas"
                     /locus_tag="LSX49_002027"
     CDS             complement(30624..32783)
                     /gene="aas"
                     /locus_tag="LSX49_002027"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HBL7168444.1"
                     /translation="MLFSFFRNLCRVLYRVRVTGDTKALKGERVLITPNHVSFIDGIL
                     LALFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAI
                     ARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQLKQQPEEEALILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENIRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            33369..34400
                     /gene="galR"
                     /locus_tag="LSX49_002028"
     CDS             33369..34400
                     /gene="galR"
                     /locus_tag="LSX49_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HBL7168445.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETIGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIPANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(34407..35669)
                     /gene="lysA"
                     /locus_tag="LSX49_002029"
     CDS             complement(34407..35669)
                     /gene="lysA"
                     /locus_tag="LSX49_002029"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBL7168446.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVLEFGQD
                     LQAISAGGGLSIPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     AGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            35791..36726
                     /gene="lysR"
                     /locus_tag="LSX49_002030"
     CDS             35791..36726
                     /gene="lysR"
                     /locus_tag="LSX49_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HBL7168447.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERIRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAVKKVLTPDDFHGENYISLSRTDSYRQLLDQLFTENQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(36713..37405)
                     /gene="ygeA"
                     /locus_tag="LSX49_002031"
     CDS             complement(36713..37405)
                     /gene="ygeA"
                     /locus_tag="LSX49_002031"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBL7168448.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCSLPFL
                     HIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADDRAKINQI
                     IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(37534..38952)
                     /gene="araE"
                     /locus_tag="LSX49_002032"
     CDS             complement(37534..38952)
                     /gene="araE"
                     /locus_tag="LSX49_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HBL7168449.1"
                     /translation="MVTINTESALTPRPLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
BASE COUNT         9909 a        10479 c         9350 g         9350 t
ORIGIN      
        1 gatggcgtga ccggttactg tatttatatt ttgaaattat gaatttgctt taatgccgag
       61 tgcacctcct ggatgatata agccgaaatc agcacgagta aattttttca attcagagag
      121 tgcaagcgcc accgcatcac caacaaccag aacaacagtc gacgagcatg acggtgctaa
      181 acctaaatta tccgcctcac ttttgacggg gatttcaaca gataaatcac aacttatcgc
      241 aagcgatgag tggtgactgc gggtaaaaga gatcaaataa ttacccattt ttttcagact
      301 aggcagtgtc gccaggattt ccgccgtctc accactgttt gaaataagaa taacaacatc
      361 gtctttcgcc accattccaa ggtcgccgtg tacagcttcc gtaccgtgaa caaaaaacga
      421 gggagttccg gtgctggcaa atgttgcggc gagtttcctg gcaataatac cggacttacc
      481 aacaccaata aaaacaactt ttccctgaca agattgtaat actttaatta aatttgcgac
      541 ctccgaaaga ggggaatcaa taacttcttc aactgcttta tgttcgttac gcataaaatg
      601 tttaatgaga tggataagat ccgtgttatt catttttatt ctccctgatt aatattttta
      661 attacactca caagacgcgt aagccccata tataattttt ctcgactgca ggccaggttc
      721 agacgaaggt agccctcccc ctccgttcca tagacatgcc ccgccataat gcccactttg
      781 ccttcatgaa ttaatcgact gtagaattca tcaaaaggat aaccaatagc agaacaatct
      841 atccaggaaa aatagcaacc atcagctggc cttacgatca attctggaat attttcattc
      901 agatactgct gggtgaattg aatgttagag gcaatatgtg cctttaatga ctttaaccat
      961 ccctcacatt cgttatagcc aataatagtt gcaattatat tcagtactga tggggagttt
     1021 acaaaatcgc gatacctcga tatcgttctg aacttatgat taaaattatc gtcagttgaa
     1081 atcatatacg atcctgttag tgcaggaaca ttaaatgttt tcgatatcga gttaaatact
     1141 actacttttt ctttttttat tttaagcgcg gatgtaaagc tacgattaaa aacaaaatca
     1201 ctatggattt catctgaaca taaccagaca ttatgccttg tacagcttgc agcgatttta
     1261 tgcagttctt cttccgacca gactgttcct gtcgggttat gaggattaca taataacacc
     1321 atctttgcgc ttttaatctt aagatcaaaa tcttgccagt tgatagcgta gctcccctca
     1381 ttttttataa tcaaagaggc tgtcagaata tttcgctcgc tatgtttaat tacatcaaaa
     1441 aatgcattat agacaggtgt aaaaacgaga atattatcac catgcgatgt caataactct
     1501 attgcttttg caatagagta catcacactg gggctatagg ttatccattc aggtttaata
     1561 tctgtttgat attgttgata ataccagttt actatcgcat tcagatattc accatgttgc
     1621 caacgactgt accctaaaat cgggtgttcc aggcgttttt ttaatgctct ggtgatagcg
     1681 tctggtatcg gaagatccat atctgaaata gagaatggta gtacatcttt tacaccaaat
     1741 ctgtcctcgc aaaagtccca ttgggtacaa tatgttcctt tgcgggaaac aggagtatta
     1801 aaaacatcca tcagtatatc cccatatagt tatccatatc ccgacgcagg gcgatgactt
     1861 tagtgccgat aatgacttgt agggtatttt gatcaagttt aacaaccgca atcccgccag
     1921 ctatttttat tgcaacttcg tcaatcaatc ccatatctgc gattgttaaa cgtaaacgag
     1981 ttacgcaatt atccagtgac ttaatattct ctttaccacc aagtgcctta accatctgct
     2041 ccgccgcttg cagctctgat ttatcaggag ttgggatatc cgctatagcc gtatcttcgt
     2101 gagcgttcag cgtgacagga ctggactctt cacggcctac ggtcatcagg ttaaatttaa
     2161 gaatggtcca acggaacaca aagtaataaa tgaagaaata ggccacttcg acacacaccg
     2221 cgatcggcca acctgttctt gtgccacgca atacgccaaa gctaataaat tgaatcagat
     2281 cgccagtaaa tcccatcttc acgcccatat atggcagaac catgttagcg aatccattca
     2341 taaaggcatg gaagacaaac agcagtggac tgacaaataa gaacagaaac tcaatcggtt
     2401 cgctgacgcc gccaataatc accgtaagca ccccggaaat aagcaatgct ttgatagcct
     2461 ttctgttttg agcatgagca gtgcgataca tcgccagcgc ggcaccagcc agaccatact
     2521 gaatcatcag tttgccctgc tccattttcc ccgccaaatc cagcggaatg accgcattct
     2581 ctttgacgta cgccataaac atgttcaggg tgccgtaata ttcttcgccg ccaatcacag
     2641 ccgaaccgcc gattggcgta aagcggaaaa ctgacgtcac cagatggttt aagccaaaag
     2701 gaatcgtcac gcgttcggca actgcataga agaaataacc aacaggaccg gaagttgaaa
     2761 tccagtgtcc aatgagcatg aaaagattga aaaacggcgg ccagataaaa ggaatgatca
     2821 gaccaaatcc actcatcaca atcagtgtaa tgataggcac cagacgtggg ccgctataaa
     2881 aacctaacga ttcaggaatg cgtaaattaa cgatcttttt atacatgctg gcgactaata
     2941 acccagcaac aattcccccc aacacgctgg tattgtagga ctggatcccc agaatgatgg
     3001 tttgcccatg tgtcgacatt tggtcagcaa cgaccaataa gtcgtgctgt ttaagataaa
     3061 agttcgttcc cagatgcatc gccataaaac caattaagcc agaaaaagca ccataggctt
     3121 tatcctcttt atcttttaat aatcctaagg gaatcgctat cgcaaacaat acaggtaaat
     3181 taacaaaggc aaacaaacca agactaacaa tgaaatcaag tatggtttta attattggga
     3241 tagccagaaa tggaattaac tttgccatat catcactggc taaaccactt cccagcccta
     3301 gcatcatgcc acatacactt agcagagcaa tgggatacat aaatgccttc cccaggctct
     3361 gaaaaaaact ccaggctttc ttttgtttca tgtgggttat ctcatataaa tgttatatat
     3421 aattagtcca ttaatacttt ggtacgaata gagagatata gtttttcttc taaaattaat
     3481 tcatatttaa aagtggcata cagataccgt tcaatttcat gaattgcgcg ctgtaacagg
     3541 atgtcctttt caagaaactg ttcatagata tcaccaatat ctttctgttt tatttcttca
     3601 ttgcataaca cgcgacttga aaaatattta aggtgcatca taaatctgga atagttaaat
     3661 gaacttctgt ccacctttct gttataaaca acttcaataa gccccgtgat tatttgcgac
     3721 aactcaataa ttcgtactga ttcataatca actgaatttt cataattatt taaaatatgc
     3781 aatgctataa aaccaatctc atcatcagga agttgaacgc tgaattgctc attaatgata
     3841 gttaatgcat cgcgacttat cgcatactct gctttgtaca acgctttgat ttcatcaagg
     3901 aaaacattat taatttgtat acctgaagcg actcgggata ttgcattcga aatgtgatcc
     3961 gcaagaatca atagtagcga tggattgaga tttttttcga gatttttctc cgcatattgc
     4021 actatttttt cggcaacaaa cacatactca atatctacat gttcaatcaa tttatagagt
     4081 ttgttttttt gttcatttct gacataaaaa atccggttag ccggatgctc agggaccgac
     4141 attccatatt ttttgttgta accgacgcca ggcccagaaa tgataacctc ctgtccattc
     4201 atcgatgcct gtacacaatt attgttcatg actttttcga tgatcattcc atggctccaa
     4261 aaaaaaaggc aaggcacgtc agaagtaata actacttcaa acattgcctt gcctgattta
     4321 acagttacaa gatgattaac taatgcgtat acattacacg gaattgtgct taattaaaga
     4381 gatggtcggc ttatttttca agccgacatt caaatatccg acatcagtca caaaaccagc
     4441 gtctaatatt caggtaaatg ttatctattc gacgaaatat aaattcattg aataaataaa
     4501 aacattatcc ccttctcgcc agcgtcgccc catcggcaaa atacgcttta attcccgcaa
     4561 gaatagactc cgcaacttcc tgctggaaag tcgccgtttt cagtttacgc tcttcctcaa
     4621 cgttactgat aaacgccgtt tcgaccagaa tggagggaat atctggtgcc tttagtacgg
     4681 caaacccagc ctgttcaact tgatttttat gcagcttgtt gattttaccg agcttattca
     4741 gcaccgcttt accaaactta aggctgtcgg caatggtcag cgactgcacc atatcgaaca
     4801 tggtgtggtc gacatagcgg tcaccgcttt tgcttacgcc accaatcaag tccgaggcgt
     4861 tctgggtttg tgccagatat tttgccgcag tactggttgc gcctttggtt gagagcgcaa
     4921 acaccgagga accgctcggc tggcgactgg taaaggcgtc ggcatggata gaaacaaaca
     4981 agtcagcgcg ctgtttctgg gcttttgcta cgcgcacttg caacggaatg aagatgtctt
     5041 cattgcgcgt catgtacacc ttcatattgc cctctttctc gatcagagag cgcagacggc
     5101 gagctatttg caataccacg tctttttcgc gtgttttgta tttccccacc gcaccggagt
     5161 cttcgccacc gtggccaggg tcaagcataa tgacaatcgg acgatcccgc cctgctttac
     5221 ccggttgtgg accactttgt gctggcggca cctgcttttc gaggtcgcct ttgttgtaat
     5281 cctccagcag cgccagcagc gggtcctgca tatcctgtgc attggccgga tagaggtcca
     5341 tcaccagacg ctctttaaac ccggcgaccg gcgcaagggc aaacagctgc ggttttacgt
     5401 tttgctttaa ttcaaaaacc atacgtacgg tttgcgggtc aaattgcccg acgcgcgccg
     5461 acttgatgaa cgggtcgtca gcgcggattt gcgcagccat ccccttgagc actgagttca
     5521 ggtttacatc ttcgatatcc accaccacgc gttcaggatt actcaacgcg aactgcttat
     5581 atttcagctg acgatttgat tctaccgtca cgcgggtgta gctggacgca ggccagacgc
     5641 gcaccgccac gacctggctg accgcagcca ggctgacctg acttacgctc aatagccaca
     5701 tggcacccgc gccttgcagt aaacgacgac ggctgattgc agtgttggat cctgacatgc
     5761 ctctcccgag caaaagaaat ctaagctgtg taacaagtaa acgaccaatt tgaccggaaa
     5821 ctttagcgaa agacgcataa tctgtcatct ataaaacggt aaacattctt tttatattca
     5881 cggtattact gataaaaaac tcgctcccgc ataaaattta cacttgcacc ctgcgaaaaa
     5941 acagaataaa aatacaataa tttagaataa tcatgcaaag aggtgtaccg tggtaaagga
     6001 acgtaaaacc gagctggtcg agggattccg ccattcggtt ccctatatca atacccaccg
     6061 gggaaaaacg tttgtcatca tgctcggcgg tgaagccatt gagcatgaga atttctccag
     6121 tatcgttaat gatatcgggt tgttgcacag cctcggcatc cgtctggtgg tggtctatgg
     6181 cgcacgtccg cagatcgacg caaatctggc tgcacatcac cacgaaccgc tgtatcacaa
     6241 gaatatacgt gtgaccgacg ccaaaacact ggaactggtg aagcaggctg cgggaacatt
     6301 gcaactggat attactgctc gcctgtcgat gagtctcaat aacacaccgc tgcagggcgc
     6361 gcatatcaac gtcgtcagtg gtaattttat tattgcccag ccgctgggcg tcgatgacgg
     6421 cgtggattac tgtcatagcg ggcgtatccg gcggattgat gaagacgcga tccatcgtca
     6481 actggacagc ggtgcaatag tgctaatggg gccggtcgct gtttcggtca ctggcgagag
     6541 ctttaatctg acctcggaag agattgccac tcaactggcc atcaaactga aagctgaaaa
     6601 aatgattggt ttttgctctt cccagggcgt cactaatgac gacggtgata ttgtctccga
     6661 acttttccct aacgaagcgc aaacgcgggt agaagcccag gaagagaaag gcgattacaa
     6721 ctccggtacg gtgcgctttt tgcgtggcgc agtgaaagcc tgccgcagcg gcgtgcgtcg
     6781 ctgtcattta atcagttatc aggaagatgg cgcgctattg caagagttgt tctcacgcga
     6841 cggtatcggt acgcagattg tgatggaaag cgccgagcag attcgtcgcg caacaatcaa
     6901 cgatattggc ggtattctgg agttgattcg cccgctggag caacaaggta ttctggtacg
     6961 ccgttctcgc gagcagctgg agatggaaat cgacaaattc accattattc agcgcgataa
     7021 cacgactatt gcctgcgccg cgctctatcc gttcccggaa gagaagattg gggaaatggc
     7081 ctgtgtggca gttcacccgg attaccgcag ttcatcacgg ggcgaggttc tgctggaacg
     7141 cattgccgct caggcgaagc agagcggctt aagcaaattg tttgtgctga ccacgcgcag
     7201 tattcactgg ttccaggaac gtggatttac cccagtggat attgatttac tacccgagag
     7261 caaaaagcag ttgtacaact accagcgtaa atccaaagtg ttgatggcgg atttgggtta
     7321 agcgatgcaa atcgccggat gcgacatgca caacattcat aggtatgata agacccacat
     7381 gcgtcgcatc aggcaattac gtttatcccc gtgaactaaa caacgccgcc agaccactgc
     7441 gccgctcggt gcgcgtggca attgccgcac ttaaaatgcg ctcatcggca tacagcgaca
     7501 gacggcgacg cgcgcgggtc accgcggtgt aaaccagctc tcgcgttact accggcgtgc
     7561 gttgactcgg taaaatcaac gccgcatggt cgaactccga tccctgcgat ttatgtaccg
     7621 tcatcgccca cgtcgtttcg tgctctggca ggcgactcgg ttgcacagac ttaatattgc
     7681 cgtccggcat cgcaaaccag acgcgcgtcc cctgcccgcg atccagcgca ataccaatat
     7741 cgccattaaa caacccaagc gcgctgtcat tacgggcaat catcactggt cgaccttcgt
     7801 accaacgaga gtgcggatga cgatgaattt tgcgcttctg ttgcataaat tgctcaattc
     7861 gctcattcaa tccagccacg ccaaacggtc cttcccgcag ggcgcacaaa agctggtact
     7921 cattgaacgc ctgaatgatt aaatccggct cggcacgcgc ttgcagcaga tccagataac
     7981 gtccgtaacc cgcaagaact tcctcaagca tcgcaatata atcttcgcca ctctgtaaaa
     8041 gccgtttttc gatatcagta aaatcctgct gaaaaacggt tttcactgcc gttttatcac
     8101 ctcggttaat cgccgcagct aactgaccaa tgccagaatc gctgccgaaa cgatagcttt
     8161 tttgcagcag gcagaggctg tcgcgcaaag atgccgcttc tgtgccagtt cctgctggaa
     8221 cgtggcttcc cgtcaggcgg ctcaactgcc cggcacgctc ggcggtaaag cccgcgttgg
     8281 cataagcgca gatatcgccc agcacagccc cagcctcaac cgaggccagt tgatcacgat
     8341 cgccgagaaa gatcactcgc gcatgatcgg gcaaggcgtc gatcagtctc gacatcatag
     8401 gaagatcgat cattgacgct tcatctacca ccagcacatc aagatgcagc gggttaccgg
     8461 catgatgacg taaacgctgg ctacccggct gcgcgcccag caatcggtgc aaagtgctgg
     8521 catcttccgg aatgcgtttc ttttgttcag cggtcagcgg taactgtcgc aaagccttgc
     8581 cgagagattc ggttaagcgc gcggcagctt tacccgttgg tgcagccaga cggatacggc
     8641 agcgttctcc gtcggccatt tgaattaagg ctgccagcaa cttcgctacg gtggtcgttt
     8701 taccggtgcc aggaccgccg gaaatcaccg aaatccgccg cgtcagcgcc actgccgccg
     8761 caactttttg ccagttaatt tcatcgctta ctggaaaaag tttgtccagg gtttgcgcca
     8821 gtagagcttc atcaacctca atggcatgat tcacttcgtt gaaaaaacgt gccactgtgc
     8881 gctcgttaca ccacatgcga ttcaaataaa gacgatcgcc acagaggatc atcggcgttg
     8941 gttcatctcc ccggctgacc gcttgtgaag ccagcaagca ttcttcccaa ttttgtagct
     9001 caccgatttc actgacacag gtcgccaaca gcggatgcga cgcctcgtta ttttccagtc
     9061 gtgaaagcgg caaacaaacg tgtccctctc cggcatcatg acttaatagt gccgccgcga
     9121 gggtgacggc aggatgttca tctcccgcca cggtcagggc aaactgcacg tccagcgggc
     9181 gtagctgttt gtgctccaca gcttccagta attgcttttg caatttcatt acgcctcctc
     9241 cagggtcata ccggcaaaca tctcatccat caggtcaatc aacccggcgt tgggtcgggt
     9301 cgcgtagatc ccttgttgcg gatgttcttt atcaacgcca cgcaggaaca gataaataac
     9361 gccgccaaag tggcgctcat agtcgtaatc agcaatacga tggcgcagat aacggtgcag
     9421 cgccagggta taaagctgat attgcagatc atagcggtgt gcctgcattg ccgctgccat
     9481 agcctgttgg gtgtaagccg aactgtcttc acccaaccag ttggatttat agtcgagcag
     9541 gtaataacgc ccttcgtggc ggaacaccag atcgataaag ccttttaaca tgccacgtac
     9601 ctgcatgaac tccagcggcg ggcagccagc agatagcggg tcaaactggc gaattagtgc
     9661 atcaagctgg ctggcgatga gcggttcgct aattggcagg taaaactcca tctccacctg
     9721 tttatcgcga tcggaaagct gactcaggct aatacccgtt tcattgagag gtgccaggag
     9781 gacagccgtg atccactcag tcaacaccgg ttcccactgc ggttcaaagc caccgagctc
     9841 cagtttttcc tgtacccagt tcgggtcaac cggctgggta aaatcgaggt cttcaaacaa
     9901 actgtgcaag aatgtccccg gtgacgcacc gcgcgggaac tgatgcggtg ttaacgtcgg
     9961 tacttcaacg acgctgacca cgcctgcggc atcaacatcc aaccgtggca tcagatcctg
    10021 agcgataccg tgaccacgct gctgcaaacc ggagtagctg gtgacacgcc agttatcgcc
    10081 gggcaatcgt tgtagcgtcc tcgcattcag ttctgcagtt aatgcatcat taacctgcca
    10141 gggctggtta tcaccaattt gtgccgtttg ccaggcaata tcatcatcgc acaacgcttc
    10201 aatgcaggta cgaagccctg ccacatcttg cggttctcct ttttgcagca aacgcccgag
    10261 cgcactttgg tggacgtcgg tatcaccttt tttatcgcca cgacggcgca ccagcggtgc
    10321 aacgccgaga ctgcaatgcc aaaccgaacg cgtcagcgcc acgtaaagta aacgcagatc
    10381 ttccgccaga cgttcggcct ccgcgaggtc gacgctttct ggcgcagcat taagatccag
    10441 aacggcctca aacgagtggc gatcgtgata aaacgcctga tcctggacgc ggaaattggt
    10501 aataaatggc aaccagacca gcggatattc cagccctttt gatttgtgta tcgtgacaat
    10561 ctgcaccaga tgtttatcac tttcgaggcg catttgttgg ctggaggcat tactgtctgg
    10621 ctcgaggata tgttgcgata accagcgtac cagcgcatgt tcactttcca gctgcgttcc
    10681 ggcttcttgt agcagttcgc tgatatgcaa gatatcggta agacgccgct caccgcctgc
    10741 cgttgccagc aagttttctg caatgttacg cgccgacatc agcgcccgca gcatcggcat
    10801 aacgccacgt ttgcgccaga tttgccgata accatcgaac tcttcgacta ccgcatccca
    10861 cgcatgttcg tcattattca gcgtttcaat atccagcgca ttcagcccca tcattgacgt
    10921 tgccagcgca ctgcgcaggg tgttctcacg ttcgggcgtc atcaccgcct gcaacagcca
    10981 aagcatctcc tgtgcttcca gagtttcaaa aacactgtcg cggttcgaaa ggtaaacgga
    11041 agggatttcc agcagcgtta aggcatcgcg cacctgagcg gcctcctggc ggctgcgcac
    11101 cagcacactg atgtccgaag cacgcaccgg acgcgcatcg tcgccgttca tcagcaacgc
    11161 ttcgccccgc tgtccggctt gtagccagtc gcggatttgc gcagcacata cctgcgccat
    11221 ggtactttga tagtcgccaa cgccgcagct ttcgccttcc atcagccaca ttttcatcgc
    11281 aggctgcatt tcacctttaa acacaaagcg taacgcctga tttttcccgg cagatttcac
    11341 aggaataaac ggtatttcac gaaacatgaa cgcgtcatca gtctggctga aaagtttgtt
    11401 aacgctgttc accattcccg gtgcggaacg ccagttggta tctaaggtgt agtgagcatg
    11461 aacttcgcta cgcgccttca tataagtgaa gatatccgca ccccggaatg catatatggc
    11521 ctgtttcggg tcgccaatca gcaacaatgc ggtttccggc tgatggtgcc agatacggcg
    11581 aaaaattcgg tactgctggg ggtcggtatc ctgaaattca tcgatcattg ccaccgggaa
    11641 tcgcgtacgg atcgccgctg ccaatacctc gccgctttca ctacgcagcg cggaatcgag
    11701 ccgacttaac atgtcatcaa aacccaattc gccacggcgg cgtttttcac gcgctactgt
    11761 ttcgcggatc tcagccaatg cgcgggtgat caccagatcg cggatcgaca atggttctgc
    11821 aagcagttga tcgatcgcct caaacagtgg atgtcgcggg gtttcccccc cggctttcgt
    11881 gcgatcttct aagaaacgct gagagaattt ttccagcgac tccggcaact gatagctatt
    11941 ggtctcttct tctgcccagg cgctgatctt ctcgatccat ttagcctgat tgctacggtt
    12001 aaacttgcgt cgatcaatac cagaagattc gatcagcgca tccagttcac ccactgcgtc
    12061 gcgccactgc tgttttacgg catcaatacg cgccacaatt tgcgcgtggc gggaagccag
    12121 cgtttcatca tcggggggcg gtgctttgat aactggcgct tcgccttgca gataacgatt
    12181 aatatcgcgc agcaacgcct gcggcccttt ccaggtttca aagacgacct gggcaatttc
    12241 acgcggcagc gggtagcagt ggcgacgcca gaaatcggcg caggcctggt agcgtagcag
    12301 agactcatct tcaatcagct gctgctcaaa cagcatgccg gattcaaagg cattcaggtt
    12361 gagcatgcgc tggcaaaagc cgtggatagt aaagactgcc gcttcatcca tctgccgctc
    12421 ggctaacaac aaccactgcg cggcttgcgc tttatcgtcg atctcttcca gcaggcgttt
    12481 gtacagtgga ttgtcggtgg tttcacgcag acaggcgatg cgcaactcgt ggatattgct
    12541 acggatacga ccacgcaatt ctgccgtggc agcctcggta aaggtcacca ccagcagttc
    12601 ttcaacggtc agcgggcggg gaaaggcggc cgaaccgcct agtccaagta acaggcgcaa
    12661 atagagcgcc gcaatcgtaa aggttttgcc tgtgccggca gaggcttcaa tcaggcgctc
    12721 gccctgtaag ggcaagcgca aaggatctag tgtctcggcg acatcactca ttcttttcac
    12781 tcatcagggg cattgtttgc tgcaacgcgc tgacgttctc ccacactttc cagccttcag
    12841 gatgcacata ttcggctttc ccattctggc tgccggaaat ctgcgacaga atagccatac
    12901 cttgcggctc gaccaccgcc tgatggaaga aatcagcaat tttttgcggc gtcagcagtt
    12961 ttatctgggc cacgatttta tcacgcgaat cgaagcgcat attgccgcga tcgaaatctt
    13021 tacttaactt cgatgcttct tcgccgagcg tttgcggtgc ctgcagcatc tgggtaatta
    13081 ccgcctgctg gatttgcgca aactcttctg gcttcatcgc ccgcaatttt gcctctgcgg
    13141 ttgggaaaaa cgccttgtaa cgctcccaca agaatgaagg ctgtttatca ttgctttgca
    13201 aaaggaagcc catgccccac tgacgcccca cgctcattgg aaacgcaaac acggcatagc
    13261 ccaactgttc ttcggtacgc aactgattgt agaaccacgg ctgtacgatc tgccccaaca
    13321 gagaactata cgctgagctg gtgtattcat cgtagccagt cggtacaaat accgctgcca
    13381 gtgcggagtc ggtgctgtta ccggcttttt caaagatgac ggattgtttt ttatcgacca
    13441 cgacatcttt gttacgacac cactctgaac catcagcgcc caactgtttt tgcacatggc
    13501 gtgccagcgt tattgcctgg gcttcagtca tgttgccgat aaccataaac tctggtctag
    13561 cccctgattt taaggcgtcg cgataggcca gcacctcttt caacgtaatg gagggcaaaa
    13621 ttttgcgccg ttcatctcgc gagaagtacg gcacttgcga gagcatctgc gcgggcataa
    13681 tcgcctgctc gaacgctttg cccttttctg cggaatccat catctggtta taccaggact
    13741 tcgcctgctc aagctgatct tccgtagcgg tatagctaaa gtagccctcc agcagagcct
    13801 ggaacagctg cggcagacgc tgggtgtaac cattagcatt aaccataagg ccgttgttag
    13861 cattggtgga aaaacttatg ccaccaaccg acgcctggtt gcttaactga tcaagcgcca
    13921 gccctgcgag ataatcattg agtgcaaaca tcacctgatt gcgggcgctg tccatggctt
    13981 tcggattacg caaaatcagg ctgacatcag ctttgggctc gctggcaaaa taacggcttg
    14041 gcgcatacac cacgcgcaga ttcgactcat caacaatcaa ctctggatgg tcgtatttct
    14101 tctctgactt aatcagcgag aaatcgtcag gaatataggg gttaagctcc ggtaaggaga
    14161 gcgcaatatt ggcggctttt ttctgccagt cagcgaaagt ttgtgcgcta attttatcga
    14221 cctgatacgg cgcatcgaca aagtaagccg ttttgttgtg cggctctttc gggctgatat
    14281 accagatacg cgcattctgt ggcgtcatca tcgccagacg ttcttttacc gctttagcgt
    14341 cgtaccgatc ggcaatattg actgcatcca gtgtatgctc aacaggaacg cgaatcatgg
    14401 tatctgccag ccattcgacg taatccatat cacgggtgat tgacggataa cggaagtcga
    14461 tatccagcac attcgccagt tcatcgaagt attgtttatc gatccctttt tcacgtaaca
    14521 gattgaggta gctaaaaatg gccgccacaa cctgatcgcg attcgccaga cctttatcgg
    14581 ttaaagacgc agagatcgct aatacgccgc tgttgccgtt gacgatagga tcggaattgg
    14641 cgctaatgcc ctcaactaat ccctgctttt gcagccagtc agaaagtgta ccagggctgc
    14701 gattaccaat cagataggta atcaattcat ccgttttact acggaacttc gctgaattgt
    14761 tatcgatgcg aaactcaacg cgcagaactt tacgcggcag cgccgggacg taatgaatga
    14821 taatgccctt ttgcgcgtcg gtgactaccg gcacggtgat ttccggtttt ttgctctctt
    14881 tgttcggcac gcgaccaaag gtgtccgccg ccattttcgc caactccggc aacggtttat
    14941 tgctgtaaat aaccgccttc atcagattgg cggaatagta cttctcgtgg aaatctttca
    15001 gcgcctgctg taccggatta cctggtttgt cgcttaaagt ttcgaggtta ccaccagaaa
    15061 actttgaacc ggggtgtgcc gggttaatgg tttctgcgct gacctgtgcc atgcgcatcc
    15121 cgtcacgcgt acgcgccatg gttaattcgg cattcactgc attacgctca cgttcggcgt
    15181 atttcttgtc gagcaagggt tctgcaatag catcggccag gcggtctacc gcaccgggta
    15241 aggcatcgtt ctcaacttcc agatagaaag ccgtgcgata cggtgccgtg ctggcattgt
    15301 gactgccgcc gtgcattttg agatattcgg ccagactgtc agcctgcgga tactttttcg
    15361 accccatcag actcatatgt tcaaggtaat gtgccagccc ctggtacgcc tcaggatctt
    15421 ccagcgaccc aacgggcacc accagcgccg agagcgattt aactgcctgc ggatcagaaa
    15481 ccagtaagac caccataccg ttatccagac gtatagcctg atactggcgg ttatctttat
    15541 cacttttacg gatggtttcc tgaatcggct gccatcccgt ttctgcctga cttaagggtg
    15601 cccagagggc aacaaacaac aataatgctt tgaaccagat gctgcggggc attcacggac
    15661 ctcataatca actttatttt ctggccagat tcaacacgtt aacgcaaatc atctgccaga
    15721 atttaatctt gtgctgaacg agtcagccta tgtctatata accatcagtc cgtgactggt
    15781 gcgcatcata aagtaagcgg atagattgcg caatttttat acaacactca tgactgatta
    15841 aagcgaaaca gcggtaacag gaaacgttgc gactgttcaa cgatagcctc cattgtctct
    15901 ggtgttaatt gccgccagag ccgttgatac cagatatcat caccttcgcc acgcaccatc
    15961 atgttgcctt cgtaagcctg aaggaatttc gtacgggctt tttgcaacgt ggaatcgtca
    16021 tccagcatgg catcgttttg cgcgtcataa caggttttta gccacgcgcc gccactttca
    16081 ggtaacacca gcaatggcgc ggacattcct tcacgatacc cctcaatcag ttgtgagagg
    16141 taatgcaaag cctgttcggc tgcaagcggc ggaaaacgcc actcgccgtc tttgcgtaga
    16201 aaaaggcgac tttcaccatt accaccgctg gcacagtaga caaggtgttc cagccaaagt
    16261 tgcattccct gcgccacact taataaagag ggacgccagc gcaacaggcc atccggctgc
    16321 acctgcggca accagcccgt tatttgcaca ccgttgcagg cgagatcaat ctccatactc
    16381 tgccccggct ggcgacaggc aatgactctg tcggcaagct gctgcatctc ctgacactgc
    16441 gtttcccaga aaatttcacc aaaagcgcca tacggtaaat cccctgccgc ccggaagcga
    16501 cggaacaagc gttcggcatc atcctgctca accagtgcat tcaataactg ctgattgatt
    16561 tgataacggc taagtccttc cagaataaat ggctcggtgt cggggatttc gctgtcttcg
    16621 gtacggaagt tcacctgcaa acgcatctgg aaaaatgccc gcaccggatg tgcccagaat
    16681 cgttgtagcg tttccagcgg cacggtttcc ggtaaggtaa atggcagcgg ctgaacaaat
    16741 tcagaatgtg ctttaccagc ctggctggcc gcaggtagcc attcacgagc ataactttgt
    16801 cgttcgcctg gctggtagtt ttgtggatca aacggcattc gggtatggag gcaagtaaga
    16861 tgcgctttta cccttgcctc gctttcatca cagttgagcg cttcatcgcc cggtagataa
    16921 tggctttgcc cgatgtagtc gatcagttcc tgcaccagta ccgacgggaa acgttcactg
    16981 ttatcctgaa tggaacgccc gatatagctg atatagagtt tttgctgcgc ggaaattaac
    17041 gcttccagga acagatagcg gtcgtcatcg cgacggctac ggtcgccacg cttcggtttc
    17101 tggctcatca gatcaaagcc caatggcgca agctgacgtg gataaacgcc gtcgttcatt
    17161 cccagcaggc aaaccacttt gaacggaatt gaacgcattg gcatcagagt acaaatgtta
    17221 accggtccgg cgagaaaacg ctggctgata cgttcttgat ccaggcgctg tgccagttca
    17281 tcacgcaata gtgacagcgg caccgcgtcg ccatactgcg cacctaaacc ttcggcgata
    17341 atcgcctgcc attgttgttc gatcagcgtc atcgccgctt cggtttccgc atccggcagg
    17401 aagaaggcgt tgagcatatc gcgacaaacc ggcaaccact cttccagcgg acgctcctgc
    17461 gccagcccgc gacgccagat atttagctgc attagcagtg aagccagatg ccccaccagt
    17521 tctgcaatta agccgctcga ttcatcataa ggtagaaccg attgccactc gccctgcgcg
    17581 ctctccatcg cgtagcccag caacatgcgc gtcaggccaa accgccaggt gtgttgaccg
    17641 gtagcgggaa gttccagctc gcgaacgttg tcgtcatcta tcccccaacg aatgccggac
    17701 tcgttgaccc actggcgtaa ataacgcagc ccttcttcgg tgatgtcaaa ccgcgccgcc
    17761 agcaccggca catccagtaa tgccagcacg tcttccgaca caaagcggct gtctggcaac
    17821 gataacaggc tgataaacgc ttcaagtaca ggatgcgact gccgcgcccg acggtcggaa
    17881 atggcgtaag gcaggtaacg atccgcaggt gcgctaccaa acacagcctg aataaacgga
    17941 ctgtagctgt cgatatcagc caccatcacg atgatgtcgc gcggagtaag tgtcgggtct
    18001 tcctccagca tcgccagcag gcgatcgtgt aaaacttcaa cttcacgctg cgggctatgg
    18061 caaacgtgga aggtgatact gctatccagt ggatcaagcg ggcgtttgtt atcgctacgg
    18121 gaaaactctt cgatgttcac accagcaacg gcgcggtttt ccagttccag aatgtcagac
    18181 tgaatattat gcagcaggtt atctggcgtc acatcgacaa aagcgtccag ctcctggctg
    18241 ctctccaggt cagaaaggag ataaatgtag tcgcgcccaa gcttgcccca tgaagccagc
    18301 agcgggttgc cgacatcctg ttcaccatcg ctgttaaaga gctgcccggc attttcgctg
    18361 tcgcgaaata gcggtaattc gcgatcttca aaactgtgtc ggcgctggcg agtcagtagt
    18421 ttcgccagat aagcgggatc tttaatgtcg ccccagtaat aacggcaggg gttggtaaac
    18481 aggagatgga tttcaatatg tttacccagc gcctgtagcg cctggagata aacaggcggt
    18541 aacgcggaaa taccgcatat aaagacgcgc gaaggtaacc ccggcgggca ggtcgtcgcg
    18601 gactccagcg tttcgataaa gcgctgatag agattggcgc ggtgccagcg cggttgccca
    18661 agttcgtcgg tatattccac caacgccttc cacaacggcg cttgccaggc ctgtgcttct
    18721 cccaaccctt ctaccagatg tcctgtttcc cactgtgcca gccagtccgg acgatagacc
    18781 agatactggt caaacaggtc cgccgctttt gaagaaagct ggaacagttt tcgcttgtca
    18841 ctatcgtcag tcagataatg ccgcaacagg gtaaagtctt cgcgctccaa cagttgcggc
    18901 agcagtgtca tcagtttcca gctcatgctc tgtttgttaa aggcgctctc tttggggatc
    18961 tccggtaaca cccggacgaa catatcccag ataaagctcg ctggcagcgg aaaatcaatg
    19021 tttgccgcaa taccaaactt ttgcgacagg gtcatttgca gccactgtgc cataccggta
    19081 ctttgcacca gaatcatctc tggttcgaaa ggatcgtcca gccgttcgcg ttcgacaata
    19141 aactccatca acgcttccag cacgtccaga cgattggaat ggtagaccct taacatagcg
    19201 gctcctgact actgacgatt cgggcaatgc aggcgggtca tctcgccttc tctgcccccg
    19261 ggtgaaacta gcgtaacgct gatgctgaca catcccgcct gcgatgtctg cattcggttg
    19321 acctgccagt tagcaggtgg cgaaatcgcg cgcagttgcg tttgctgcca gccatgccgc
    19381 cagagctgtt ggtactggtt tctgctggca agactgttca ttaatgttcg ctggaaaccc
    19441 gataacgcag tgacaatcat caccatcaac accatcgcca acattacctc cggcagacta
    19501 aagccttgtt gattcctcag ggaagctgac ataacgccct ctctttcagc ggacaaaaat
    19561 cgctccagcc gcgtggcgaa aaaacaatgt ttccatcgat gacttcgcct gttcgccaca
    19621 acgaaacgcc ttcataacca gcaatcaata aggcttcatt atctgccagt aaacgcagac
    19681 aaacccgggc accggtggca gcatacagta agcactgaac tgcgggcagc gtctgccagg
    19741 agtgcatttt tccccactcc agcgccgact gaacgatggc ctggcggcgc aatgactgac
    19801 tttccatgct cacgcgagaa gcaaaactgc gatcctgctg actcattcct tgcaatagca
    19861 agctacccaa aatcagcagc atcaggacca gagccagtga cgaaacaccc ttttcgcggt
    19921 tcacaggttg gatcctgtca cgctatagct ggcatccacc acggtttgcg gatcagcctt
    19981 gctggcagcg tgcatattaa ccgtcaacac cggcgagaag ccgctgacat cctgacgtac
    20041 gacctgaaaa gtgtcgataa tgatggcatc cggattagtg actttatccc agcccttacc
    20101 ttcacaggat gtcgcaccgc gtagcgtttc cagcacatgc tccttcagac gaaatccaat
    20161 ctggtcggac tcttttaccg gttcgcgatc ccagatacca ttactgttcg catcccactg
    20221 cacaatgaca cagtcaccct gtccgacaat ttccagccct tcgcccgtac agctgccatg
    20281 gcaataaccc gccctctgga gatgcttcgc gacggtaaat acccgcagcc agatttcatc
    20341 ttccagcgcc agcttacggg tgttcgttaa actttcacgc tgtaacgcag gcagaaagcg
    20401 tgcagccccc agcaacaata cgctactgat cgccatagca atcaacactt ccagcagaga
    20461 aaaaccttgc tcttttacag gcatccttct gtttctcctt gctgacaaag ccggagtctt
    20521 ccccacggcg aaaccactag ccaccactcg cccgttgagt ttttgaagcg aatatgcccg
    20581 gcccatgcgg tattgcgcag gccaaagaaa gcaagcgaag gtgtcaggtc gctcatttcg
    20641 acttcgggcc agcgcggcac aaagaccaat ggtgaactgc catgacaggt attcgcccca
    20701 gcaacggaac tcacaaggca ccataacgtc ccctccctga taagactgat actgtggtcg
    20761 cggttatgcc agttggcatc ttcacgtaaa tagagcaaat agtcccgcgc ctggctggcg
    20821 gtttgccaaa gccgttgcga ctgctgccag tattgccagc catagagccc acttgcgctt
    20881 agcatgacca gaatcagcat cgcgaccagc gtttcaatca gcgtataacc acgttgtttt
    20941 ttcatgccgg cagtatggag cgaggagaaa aaaagacgag ggccagtttc tatttcttcg
    21001 gcgcatcttc cggactattt acgtcgttgc aggacgttgc aaaatttcgg gaaggtgtct
    21061 cgaagaattt aacggagggc aaaaaaaacc gacgcacact ggcgtcggct ctggcaggat
    21121 gtttcgtaat tagatagcca ccggcgcttt aatgcccgga tgtggatcgt atccttcaat
    21181 ctcaaagtct tcgaaacggt agtcgaagat ggattcgggt ttacgtttga taatcaactt
    21241 cggcagcgga cgcggttcgc ggcttaattg cagatgagtt tgatccatat ggttgctgta
    21301 cagatgcgtg tcgccaccgg tccagacaaa atcacccact tccagatcgc actgctgcgc
    21361 catcatatgc accagtaacg cgtagctggc aatgttgaac ggcaggccga ggaagacgtc
    21421 acaggagcgc tgataaagct ggcaagagag tttgccgtct gccacataga actggaagaa
    21481 tgcatggcac ggtgccagcg ccattttatc cagttcgcct acgttccacg ctgaaacaat
    21541 aatgcgacgg gaatccgggt cgtttttcag ctggttcagt accgtagtga tctggtcaat
    21601 atgacgacca tccggcgttg gccaggcgcg ccactgttta ccatacactg gcccgaggtc
    21661 gccgttttca tcggcccatt cgtcccagat ggtgacattg ttttcgtgta gataagcaat
    21721 gttagtgtcg ccctgcagga accacagcag ttcgtggatg atggaacgca ggtggcaacg
    21781 tttagttgtc accagcggga atccatcctg caggttaaaa cgcatctgat gaccaaaaat
    21841 ggaaagcgtt ccggttccgg tacggtcgtt tttctgtgtg ccttcgtcga gcactttttg
    21901 catcagttct aaatactgtt tcatggttcc tcaggaaacg tgttgctgtg ggctgcgacg
    21961 atatgcccag accatcatga tcacacccgc gacaatcatc gggatggaaa gaatttgccc
    22021 catgctgatg tactgcaccc aggcaccagt aaactgcgcg tcgggctggc ggaaaaactc
    22081 aacaatgatg cgaaacgctc cgtaaccaat caggaacaag cctgagacag ctcccattgg
    22141 gcgcggttta cgaatataca ggttgaggat aataaacagc accacacctt ccagcagcag
    22201 ctcgtaaagc tgtgatgggt ggcgcggcag cacaccgtaa gtgtcgaaaa tggattgcca
    22261 ctgcgggttg gtttgcagca gcaaaatatc ttctgtacgg gagccaggga acagcatggc
    22321 aaacgggaag ttcgggtcaa cgcggcccca caattcaccg ttaataaagt tgcccagacg
    22381 cccggcacca agaccaaacg gaatgagtgg agcaataaaa tcagagacct ggaagaagga
    22441 acgtttagta cggcgggcga agataatcat caccacgata acgccaatca ggccgccgtg
    22501 gaaggacatg ccgccgtccc agacacggaa aagatacagc ggatcggcca taaactgcgg
    22561 gaaattgtag aacagaacat aaccaatacg tccaccgagg aagacgccga ggaagcccgc
    22621 atagagtaag ttttcaactt catttttggt ccagccactg cccggacgat tcgcccgtcg
    22681 tgttgccagc cacattgcaa aaatgaaacc caccagatac atcagtccgt accagtgaag
    22741 cgccacgggt cctattgaga aaatgaccgg atcaaactcc ggaaaatgca gatagctact
    22801 ggtcatctgt caccacaagt tcttgttatt tcgctgaaag agaacagcga ttgaaatgcg
    22861 cgccgcaggt ttcaggcgct ccaaaggtgc gaataatagc acaaggggac ctggctggtt
    22921 gccggatacc gttaaaagat atgtatatga tccgcgctat aaccccccac gaatcagccc
    22981 gcccatgccg cgacgctcca taaaggctgc aacctgatgg cgaacttcgg tcgccagttg
    23041 cgcttccaga ctacgctgcg caagattttc tgcttcggca aaatcaatgc gccgcagcag
    23101 gtattttacg cgcgctacag aacgtccgtt catagacaga tggcgatacc caagcccaat
    23161 gaggattgcc acgcacatcg gatcgcccgc catttcaccg cacaaacgga gatcgattcc
    23221 atgtatttcc gcttcccggg cgatcatcgc cagagctcgt aacattgcag gatgaagact
    23281 gtcataaatg ttcgccaccc gggtattgtt gcgatcaacg gccaggatgt attgcgtcag
    23341 atcgttggtg ccaacagaga tgaaatcgac ccgctttgcc agatgcggca gcataaacac
    23401 cattgacggc acttccagca tgatgccgat acgtggtttg ggaatttcgt aaccgatcat
    23461 ctcctcgact tcacgtccgg cacgttcaat caggcggcgt gcttcgtcaa cttcatcgag
    23521 gcttgtgacc atcggcaaca gaatattcag gttgcccgta gcggcattag cacgcagcat
    23581 cgcccgcacc tggatcaaga agatctccgg ctgatcgagc gtaatgcgaa tcccacgcca
    23641 acccaggcat ggattctctt cgctgatcgg catgtaaggc agctgcttat ctgctccgac
    23701 atccagcgta cgcaaggtga cgggtttatc attaaacatt tgcagcatcc cctgatactg
    23761 cgccacctgt tcttcttccg acggaaaacc actttgcagc atgaatggga tttcagtgcg
    23821 ataaagtcct atgccatcaa tacggctgcc cagtttttct tcatgttccg ggcttaaacc
    23881 ggcattgagc atgactttaa tgcgttcgcc gctttttaac tgggcgggta aattgacgtc
    23941 atcttccgcc agacggctaa gctcgatctc ttcactaatt agccgctgat attcttgcag
    24001 cagtaccggc tccggatcga ccagcaattc accgcgataa ccatcgacga tcagcgtccg
    24061 acgatgcagt accgaaggct gaatatccgc gcccatcacg gtagggatcc ccagcgcacg
    24121 taccatgatc gcagcatggg agttggcagc gccatcgcgc acgacaacac cgactaagcg
    24181 atcctggggc agctcagcaa gcgttgtcgc tgacagttca tctgccacca gaatgaaacg
    24241 ttccggccag gcgttcggcc cttgattagc gtcatcaaga tgaaacagca atcgctgacc
    24301 aagtgcacgt aaatcgccag cccgctcttt gagatagtta tcgcttagcg cggcaaactg
    24361 ttcggcaaat ttttcaatga ccgtttttac cgcccactct gccaccgagc ctttatcaac
    24421 ctcggcaaac aattcgcgac gcagccgggt atccgaaagc aggtgtgagt aaagatcgaa
    24481 aatagccgcc gtttcttttt gtgcaccggc agcaaagcgt ttgctatagc ggcgaaactc
    24541 gttagccgcc tcttccaacg ccccggtcag tcgttcgcgt tccagagccg gatccagcgt
    24601 tgatgcctga tacacctgtt ccattaaagg taacgtggca tcctgccagc cttcggcaat
    24661 cgccacacca ggtgctgccg gtaatgcacg gattcgcgtc tggcgatatt gcccaaacaa
    24721 ggcagtcaac tgcgactgag aaagaatagc tgccatctgg gtggcaagcg tcaccaggaa
    24781 ggattcttca ctttcgtcat actggcgcaa ctctcgttgc tgtaccacca gtacaccaag
    24841 caactggcga cgttgaataa ttggtacgcc taaaaacgcg cggaaacgtt cttcttttac
    24901 ggaggggatg tatttgaagc tggggtgctt ttgcgcatct gcaaggttta tcggttccgc
    24961 cagcctgcca accaggccga cgatcccttc atcaaacgcg agcgttacag tgcgaccgcg
    25021 tggttttttc agtccccggg tcgccatcag gtagtaacaa cgtcgatcat gatcggccag
    25081 gtagaccgaa cagacctcgg tatccatcgc aagacagatg tcggtaacca gaatatttaa
    25141 cgcctcattc aggcgtggtg cgctggctac cttttcgact atttcgcgca ggcgagtgag
    25201 cataattggc gtgacttaac ctcttttacg tcgataagca gatgcgtttt gtggttttgg
    25261 cgtattttcc tgcagtgaca tcaccacact cgcgaactct ttcattaccc tacggtagac
    25321 atcacgttta aatgacacca cctgtctgac tggataccag taacttaccc atcgccagcc
    25381 gtcaaactct ggtgtactgc tggtttgcat attgatttct gcatcgccgc tcaccagctg
    25441 caagagaaac catttttgtt tttggccgat acaaaccggc ttcgtgtccc aacgcaccaa
    25501 acgtttcggt aatttgtagc gcaaccagtt acgcgttgaa gcaaggattc gaacgtcttt
    25561 gcggcttaat cctacttctt caaacaattc acggtacatc gcctgctctg cggattctcc
    25621 ggggttgatt ccgccttgcg gaaattgcca ggagtgctga ccaaatcgcc gggcccacat
    25681 tacctgcccc tggcgattac aaatcacgat acctacgttt gggcggtagc catcgtcatc
    25741 aatcaccgga ctacctcaaa ataaagcttt atatacgaat gattgtttca tactccagga
    25801 agacggtaaa ccactctctg cagggcatta cacactaata acaattgaat aactcacagt
    25861 tatgtgcaga gttataaaca gaggaagggg tggatagccg tttttattca ccttttctgt
    25921 ggatagagtt gtgaagaact acggaattac tacgggaaaa cccggagcat tctgaataag
    25981 acagatatag agattttaaa atattcatta tcagtcaatg tattacatgt gatttgagta
    26041 ataaaaaaga gtaattcgtg acccaggtca cacctctcat ttacgggttg gcgaaagatc
    26101 aaccaacgcc gtatttatcc acagaatgtg ccactaagtt aagcactgaa ccactaaaaa
    26161 ctggagtttc gtcgcacgtc aaggctgtaa atggaaacag tagtgaaggt ttttcacagt
    26221 tatcccagct ttctgtggat aacatggtgt aagatcctgt ttattttcag tgaccagatt
    26281 tggaaaaccc gttgcagtgt tgcgcaactc gattaccggc aacctaaaaa gcaatataaa
    26341 tcagagaatt gaacaacgca tgtggaaaaa gttacactgc gaatattcgg cacataattg
    26401 ctgtttgttt tttaaccaag gtatcatgac atgtcccaac ctcgcccact gctctctcct
    26461 cccgaaactg aagaacaatt gttagcgcaa gcacaacaac tttctggtta tacattggga
    26521 gaactggcgg cacttgccgg gctggttacg ccggagaatt taaaacgcga taagggctgg
    26581 attggcgtgt tactggagat ctggctaggt gccagcgcag ggagtaaacc tgagcaagat
    26641 tttgctgctc tgggcgtgga acttaaaact atccctgtgg atagtcttgg tcgtccgctg
    26701 gaaacaacat tcgtttgtgt tgccccgtta acgggcaata gcggggtgac atgggaaacc
    26761 agccacgtgc gccacaagct caaacgcgtg ctgtggatac cggttgaagg cgagcgcagc
    26821 atcccgctgg caaagcgtcg cgtaggatca ccgttgctgt ggagcccgaa tgaagaggaa
    26881 gaccggcagc tacgcgaaga ctgggaagaa ttaatggata tgattgttct cggtcagatt
    26941 gagcggatca ccgctcgtca cggggaatat ttacagatac gaccgaaagc agcgaatgcg
    27001 aaagcgctga ccgaagctat tggtgcccgg ggcgaacgga ttctgacgct gccgcgcgga
    27061 ttttatttga agaagaattt caccagtgcg ctactggccc gtcattttct gatccagtag
    27121 ccatcgcttt gacctgccgc tttccgggca tataattacc gcttcatttt tttggcaggg
    27181 ctttttagat gttatttgca tggataaccg atcctaacgc ctggcttgcg ctcggtacgc
    27241 tgacgctgct ggagatcgtt cttgggatcg acaatattat tttcctttct ctggtggtgg
    27301 caaagctccc aacagcacaa cgtgctcatg cgcgccgtct ggggttggcg ggagccatgg
    27361 tcatgcgtct ggcgctgctg gcatccatcg cctgggttac gcgcctgacg aatccgcttt
    27421 ttacaatatt cagtcaggaa atttccgccc gtgatttgat tctgcttctg ggtggcttgt
    27481 tccttatctg gaaagccagc aaggaaatcc acgaatccat cgaaggtgaa gaagaagggc
    27541 tgaaaacacg cgtttcatca ttcctcggcg ctatcgtgca gattatgctg ctggatatta
    27601 tcttcagcct cgactcggtg attaccgctg tgggtctgtc agatcacctg tttattatga
    27661 tggctgccgt ggtgattgcc gtaggcgtga tgatgttcgc cgcgcgctcg attggtgatt
    27721 ttgtcgagcg ccatccttcg gtaaaaatgc tggcgctctc tttcctgatt ctggtgggct
    27781 ttaccctgat tctggaaagt ttcgacatcc acgtaccgaa aggttacatc tacttcgcga
    27841 tgttcttctc tattgcggtt gaaagcctaa acctgattcg caacaaaaag aatccgctct
    27901 gatactccgt acgctctcct gcgggagggc gtactcactc ctgttaccct cacagtttaa
    27961 gattttcctg ctttcaagat atataacgtc ggtttataaa cagactatta tcataggtgg
    28021 gccaaatgag gataaccgga tgaaaaaatg ggcagtaata atttctgcag tcggactggc
    28081 gtttgctgtt tccgggtgtt ccagtgatta cgtcatggcg accaaagatg gccgtatgat
    28141 tttgaccgat ggaaaacctg aaattgatga tgataccggg ctggtgagtt atcacgatca
    28201 gcaaggtaac gcgatgcaaa ttaaccgtga tgatgtttcg caaattattg aacgttaaca
    28261 aataaggtca gcatccggct ggccttaaga tttttctctt tcccttttcc cttccctctg
    28321 ccatttttat attccttatg tcgtgattat aaaaaggaaa cggctatgca atatcaccgt
    28381 ataccccaca gttcgctgga agtcagcacg ctggggcttg gcacgatgac gtttggtgaa
    28441 cagaacagcg aagccgacgc ccacgcacaa ctcgactatg ccgtcgctca gggcattaac
    28501 cttatcgacg ttgccgaaat gtacccagta cctccgcgcc ccgaaactca agggctaacc
    28561 gaaacctacg tcggcaactg gctggcgaaa catggcagcc gcgaaaagtt aattatcgcc
    28621 tccaaagtga gcggaccgtc gcgcaataat gacaaaggca tccgcccgga tcaggcgctg
    28681 gatcggaaga atatccgtga agcgctgcat gacagcctca agcgtctgca gactgattac
    28741 ctcgatctct atcaggtgca ctggccgcag cgcccaacca actgcttcgg caaactcggt
    28801 tatagctgga cagattctgc gcctgcggtt tcgctgctgg atacgctgga cgcactggca
    28861 gagtaccaac gcgcgggaaa aattcgttat ataggcgtgt cgaacgaaac tgcatttggc
    28921 gtaatgcgct acctgcatct ggcggacaaa cacgatctgc cgcgtattgt caccattcag
    28981 aacccctaca gcctgttaaa ccgcagtttt gaagtaggtc tggcagaagt cagccagtat
    29041 gaaggggtcg aactgctggc ctattcgtgc ctgggtttcg gcacgctgac cgggaaatat
    29101 ctcaatggtg caaaacccgc tggcgcacgt aatacgctct ttagtcgctt cacccgctat
    29161 agcggtgagc aaacgcaaaa agccgtcgcg gcgtatgttg atatcgccag acgtcatagc
    29221 ctggaccctg ctcagatggc gctcgcattt gtacgccgtc aaccgtttgt tgccagcact
    29281 ctgctgggcg caaccacgat ggagcagctg aaaactaacg tcgaaagttt gcatctggag
    29341 ttgagcgaag acgtattagc tgaaattgaa gcggtgcatc aggtttatac gtatcctgca
    29401 ccataagatt aacgccggtt aaaaccggcg ttaaatatta atgacggcgc tgccagatcc
    29461 acagcgccgt tattgccagc gcaaacagcg caccgaagcc aatgccaatg ggcacgaccg
    29521 ggatgcctac cattaccgcc agcgagtaaa tgcccagcat caacaacatg gcgctgtttt
    29581 cgccaaggtt ttgtactgca atcgcattcc ccgccccgac gcttttttta ccccgctcct
    29641 gtagcaacgc attgagcgga acgacaaaaa aaccccccag cacgccaatc agcatcaaca
    29701 aagcataggc tggcagcagc tcgtgttgca gggagaaaat cagtaccacc acgccaatca
    29761 aaatcccggc tggcatacag cgtgacacgg tttccagcgt aactaacttc gctgccgcac
    29821 ctgcaccaac cacgatacca atcgctacca tcgcgttgag ataggtcggc gtagcgttat
    29881 cggtaatacc cagcgccacc ggtacccaca gcaccaacag gaaacgcagc gtgacacccg
    29941 ctccccagaa taaactggtg cccaccagcg aaaaacgcgt ttcaccattg cgccatagcg
    30001 aggtgcaggc attcaggaaa ctgcgggtca tgctgatgag attccaggac tgccccggac
    30061 gcgccgccgc cagtttggga atgtagatat tggcaatgac cgcgccaccg taggccagtg
    30121 cgcatgcggc cagggcgatc aggacatgcc agtcagccag aacaccacca gctacggaac
    30181 cgagcaaaat cgccgctatg gtagacgcct ccattaaacc gttagctttt actaacttac
    30241 tacccgtggt taattcgccg agaataccgt atttcgccgg tgaataggct gcagcaccaa
    30301 cacccaccaa cgtatagccg agaaacggat tgataccaaa gcagatactg gctgcgccca
    30361 gtagcttcag gccgttggca aacatcatca cccggccttt ggcgaagcta tccgccacct
    30421 gcccgacaaa cggcgcaaaa agaatgtaag cacctacaaa caccatttgc aggatgggct
    30481 ggctccactc cggatagaac tgcgctttca gtaacgccag agtagcaaac agtagcgcat
    30541 tatcgccaaa cgcagagaga aactgcgcca cgataaccgc tttcatcccc ttcgaccaca
    30601 acgaagtgtt agtgtgcact gactcactca tcgtgttgtt ccgcttcgtc tacccagctt
    30661 ttcaacgtga caaagtcagg tttgccgctg ccaagtaatg gcatctgttt cagatagcga
    30721 atatcgcgcg gtacagcaag ctccggcacg ccgtgctcgc gggcatactg ttgtaactta
    30781 tcgcgcgtca gttcgttatc tgtggtgaaa agcaccagtg cctcgccttt gctggcatcg
    30841 ctcttaatcg cagtggcatg gactttatct ggcgaaacac caagtgccag ttgttccacc
    30901 atttccagcg acaccatttc gcctgcaatt ttggcaaagc gttttgcgcg gccctgaatc
    30961 tgcacaaagc cctgctcatc aaaacgcacg atatcgccag tgtcatacca gccgcgctcc
    31021 atttcgccgc gaatattctc ggcggtgggc acttccagta caccaggctt ctccacccgc
    31081 agatagccgt tcattatgtt cggccctttc agttgcaggc gtccgccctc ttcgatacca
    31141 ggaaccgaca acaggcgcgc atccattcct ggtagaatac gccctaccgt accgggtttc
    31201 gccgccatcg gtacgttgat agaaacgaca ggcgcgcatt cggtcacacc gtagccttca
    31261 aggatgcgca ggccaaattt atcctgccaa agctgtttgg tactttcttg tagtttttct
    31321 gcgcctgcca ccacatagcg tagacgatag aagtcatacg ggttggcaaa gcgcgcgtag
    31381 tgaccgagga aagtcgaggt accgaacaac acggtgcaac tgcggtcata caccaactcc
    31441 ggcacaatgc ggtaatgcag cgggcttgga taaaggaaca cttctgcacc tgtgagcagt
    31501 ggcgtaaaca ggcctaccgt cagcccaaag gagtgaaaca gcggtaacgc cgacataaag
    31561 cgatcgttgg tggtgaagtc ggcaatcgtt ttaatctgct caacgttcgc cagaatgctt
    31621 ttatggctat ggacgacgcc tttcggatgg ccttcagaac cggaggtaaa gaggatcagc
    31681 gcttcttctt ccggctgctg ttttaactgt gccagacgcg gcatcagcaa atgagcgaaa
    31741 atccacactt tgtcggcagt ggtgacatct gcttttaaat cttccagata gacccagcgc
    31801 acctgagtaa gttgctccgg cagatgccag agtttgcctt tatcgagaaa ctgacgggaa
    31861 gtgaagatgg ttttgatttc agccgccgta atagcactgg tcagcccttt taccccggcg
    31921 gtgtagttca tcattgcggg aatgcggcga cgggcgatgg ccccaaaaat cactgccgca
    31981 ctgatgcctg cattgggcag cattaagccg atgcgttcgc cttcaacact gtatttttca
    32041 aggatgcgtc caacaaacag cgttttcgta agcaatttgc gataggagtc tggggtaaag
    32101 ttgacgtctt cgacacattt cttcccggct ccgaagcggt acattgcgct cagtaaagat
    32161 tcgtacagcg tttcacgcgg gcgcaccgcc atacgcgcct ccatcattat ttgatgcagc
    32221 atttcgccag cgattttgcg acggtcacgg gcacgcggcg catccggcat ctccacctgc
    32281 gttggtggca aaatatgcag agtaatttgc gggaacaagc gacgtttaac cagacctttc
    32341 aggcggctga agtgcgtaag ttccgcccct tcaatacgca caggaataac cgttgcacca
    32401 gacttcgccg cgacaaatcc cgcgccatcg tagattttca tcagcgagcc agtggtggtg
    32461 atgcgtcctt cagggaaaat caccactggt cggccctgtt ccaccagacg taccagatgt
    32521 ttaatcgcca taggttgcgt cgggtcgaga ggaacaaagt cgataaatga tttcagccaa
    32581 cgcatatacc actgttggct tattgaggtg taaacggcaa ataccggacg tacgggtaaa
    32641 aacaatgcca gcagtatgcc atcaataaaa gagacgtgat taggcgtgat tagaacgcgc
    32701 tcgcccttca gtgccttggt gtcacccgta acgcgaacgc gatacaaaac acggcacaaa
    32761 tttcgaaaaa agctaaaaag cattccaact ccctttgctc tgattcagta aaagcgaatg
    32821 gagggagatt acacgagata aagaacgcga gcgacagtaa attaggtgcg aaaaaaaacc
    32881 tgcgcatccg cgcaggttgg tgcaagagac agggtacgaa gagcgtaccg aataatctca
    32941 ccaatcaata cctctgggat cttgattgtg gtctgcacga cgactcttcg ccagcgagaa
    33001 aacgcaaagg aatgaaggga aatgcaacga ggtgtgtaaa ttgtcggtta ctgttacaga
    33061 ttgatgaccg gcaaaaaaaa acctgcgcat ctgcgcaggc tggtgtaatt catgtgctca
    33121 acccgaagtt gacttcacct atcaatacct ctgggatcac cactttagca acctgaaacc
    33181 aaacgccacc agcggtcaat cgcaacagcg tttcgcaaag tgtaaccaaa ggtttgcaat
    33241 ctcttttttt gtcttactta tttgcgtttg gctcacattc ccacaatgaa aacacgccgc
    33301 cccttgaacc aacgggcgtt ttccgtaaca ctgaaagaat gtaagcgttt acccactaag
    33361 gtattttcat ggcgaccata aaggatgtag cccgactggc aggcgtttca gtcgccaccg
    33421 tttcccgcgt cattaataat tcacccaaag ccagcgaagc ttcccgactg gctgtgcata
    33481 gtgcaatgga gtctcttagc tatcacccga acgccaacgc ccgtgcgctg gcgcagcaga
    33541 ccactgaaac gatcggtctg gtcgttggtg atgtttccga tccgtttttc ggtgcaatgg
    33601 tgaaagcggt cgaacaggtg gcttatcaca ctggtaattt tttattgatt ggcaacggtt
    33661 accacaacga acaaaaagag cgtcaggcca ttgagcaact gatccgccat cgctgtgctg
    33721 cgctggttgt ccatgccaaa atgatcccgg atgccgattt agcctcatta atgaaacaaa
    33781 tgcccggtat ggtgctgatc aaccgtatcc tgcctggctt tgaaaaccgt tgtattgctc
    33841 tggacgatcg ttacggtgcc tggctggcaa cgcgtcattt aattcagcaa ggtcataccc
    33901 gcattggtta tctgtgctct aaccactcta tttctgacgc cgaagatcgt ctgcaagggt
    33961 attacgatgc ccttgctgaa agtggtattc cggccaatga ccggctggtg acatttggcg
    34021 aaccagacga aagcggcggc gaacaggcaa tgaccgagct tttgggacga ggcagaaatt
    34081 tcactgcggt agcctgttat aacgattcaa tggcggcggg cgcgatgggc gtgctcaatg
    34141 ataatggtat tgatgtaccg ggtgagattt cgttaattgg ctttgatgat gtgctggtgt
    34201 cacgctatgt gcgtccgcgc ctgaccaccg tgcgttaccc aatcgtgacg atggcgacgc
    34261 aggctgccga actggctttg gcgctggcgg ataatcgccc tctcccggaa atcactaatg
    34321 tctttagtcc gacgctggta cgtcgccatt cagtgtcaac tccgtcgctg gaggcaagtc
    34381 atcatgcaac cagcgactaa ccgcagttaa agcaattcca gcgccagtaa ttcttcaatg
    34441 gtctggcgac ggcgaatcaa ccgcgcctga ccattatcaa acagaacttc tggtaacagc
    34501 ggacggctgt tgtagttgga tgacattgac gcgccatatg cccctgtatc atgcagtacc
    34561 agataatcac ccgccttcac ttccggcaag gcgcgggttt cgacatttcc cccttcctgc
    34621 tgggtaaaga catcgcccga ttcacataac ggcccggcga cgacggtttc caccgttggc
    34681 gcgtgttcca gagaacgacc atcagctgcc agggcactga tatggtggta actaccgtac
    34741 attgccgggc gcatcagatc gttgaacccg gcatcaacca gaacaaagtg gcggctaccc
    34801 atttgtttga cgctccgcac ttgagtaatt aatacgccag cctgcgctac cagaaagcga
    34861 cccggttcaa tttccagttt cacaggatgg cccaaatggc gggcgatttg ctcacgcgcg
    34921 gcattccaca gaccataata atgttcggta tcaaccgcct cttcaccctg ttgataagga
    34981 atagaaagcc caccgcccgc agaaatagcc tgtaaatcct gaccgaattc gaggacttga
    35041 cgcaccatag caccacatac ctgttccaga tgggcataat cgacgccaga accaatgtgc
    35101 atgtgaatgc cgaccagctg tagatgatga cgttgtatca cgtccagtgc ggcgggcaga
    35161 tcggtgtacc agataccgtg cttgctgttt tcgccaccgg tattggtttt ttggctatgc
    35221 ccgtgaccaa accccggatt aacacgcagc catacccgat gccctggcga aacctgcccc
    35281 agttggtcga gcatatcaac agaacccgca ttcaccggaa tttgcaattc actgacgcgt
    35341 tcaagcgtcg cctgatcgat aacatctgcc gtaaaaacaa tatcatcagg gtgcgtttgc
    35401 ggattgtaac ccgccgccag tgcacgctct atttcaccta acgagacgga atccactttt
    35461 acgccctgct cacgcattaa gcgcaaaata tgaatattgg aacaggcttt ctgtgcaaag
    35521 cgcaccacat caaactgttt cagcgccgca atctgccgac gaataatttg cgcatcgtag
    35581 acccacaccg ggcagccaaa ttctgcgggc aaacgcagca gattttcggc ggtgagatcg
    35641 gtatcagtgc tgaacagtga atgtggcata acaaactcca gataagtgct tttttatgat
    35701 tacgccacat cataaaaaga ataaaaaata tcgatttatg tcgagtctat gcaaaaatga
    35761 tatggattac cggattgcga gagagcgcta atggccgccg ttaacttacg tcatattgaa
    35821 atttttcatg cggtaatgac cgccggaagc ctgactgagg cggcacacct gctacacacc
    35881 tcacagccaa ccgtcagccg cgaactggcg cgctttgaga aggtgatcgg gctgaaattg
    35941 tttgagcgca tacgtggacg attacatcct accgtgcaag gactgcgtct gtttgaagaa
    36001 gtgcaacgat cctggtacgg actggatcgc attgtcagtg ccgcagaaag tctgcgcgag
    36061 tttcgccagg gagaactgtc tattgcctgc ctgccggtct tttcgcaatc ttttttaccg
    36121 cagctcctgc aaccctttct ggcacgttat cccgatgtca gcttaaatat cgtgccccag
    36181 gaatcaccgc tacttgaaga gtggctctcg gcccagcgtc atgatttagg actcactgaa
    36241 acgctccata cgcctgcggg aacagaacgt accgaattac tctctttaga tgaagtgtgt
    36301 gtgttacctc cgggccatcc gctggcggta aaaaaggtat taacgccgga tgattttcac
    36361 ggtgagaact acatcagcct ttcccgtact gacagctatc gccagttgct ggatcaattg
    36421 tttactgaga atcaggttaa acgacgcatg atcgtagaaa cccacagcgc cgcgtcagtc
    36481 tgcgcaatgg tacgggcggg ggtaggcgtt tcagtggtta acccgctcac cgcactggat
    36541 tatgcggcaa gcggtttagt ggtgcggcgg ttcagcattg cggttccatt caccgtcagc
    36601 ctgatccgcc ccctgcaccg cccgtcatca gcgctggtgc aggcgtttag tgagcattta
    36661 caagcgggat taccgaaact ggtcacttct cttgacgcta ttttgtcgtc agctacgaca
    36721 gcataaaagc gacagcatcc tcggcatgga tcgccgcggt atcaaacaca ggcagaacac
    36781 tgcgctcttc tggcaccagt aaaccaattt ctgtgcagcc aaaaatgacg ccctgtgcgc
    36841 cctgttctgc aaggcgagca atcacttgcg cataataagc gcgtgacgct tcggtaaatt
    36901 gccccagaca cagttcttca aaaataatct gattaatttt cgcccggtca tccgcttcag
    36961 gaataagaca gttgatggaa aattgttccg tcagccgccc gcgataaaaa tcctgttcca
    37021 tggtgtaacg tgtacccagc agcgccacac gagtcattcc tgccccggta attgcacgtc
    37081 cagtggcatc cgctatgtgt aagaaaggca gagagcaacg agactcaatg gcatccgcca
    37141 ctttgtgcat cgtattggtg cataacacaa taccttctgc gcccgcccgc tgtaagccaa
    37201 gcgccgcctc agccagaata tccccggttt tgtcccactc accgcgacgc tggcactctt
    37261 ctatttcatg aaaatcgacg ctatgtagca gcacttgcgc agagtgaagc ccaccaagcc
    37321 gctgtttaat gccttcattt atcagacgat agtaaggaat agtggattcc cagctcattc
    37381 ctcccagcaa accaattgtt ttcattcctc tctcctgatg agtgttaccg caacaaggct
    37441 gaataaggaa cgaggcaaac gcctcaacgg ccaggtgcct aatctctatt aacgaaaaaa
    37501 gggccggatg tacagcacat ccggcccgtg aaatcagacg ccgatatttc tcaacttttc
    37561 gcctgccatc agtttgcgct cgatatgttc cagcgtgaca tttttggttt ccggaatgag
    37621 ccagaaagtg atgcccacaa acgcaatgtt cagcgcagtg tagagccaga acgtaccggc
    37681 agcgccaatg ctatcaagca gtgtcaggaa ggtcgcgccg ataatcatat tcgacaccca
    37741 gtttgtcgtc gttgagcagg tgatgccaaa atcgcggcat ttcagcggct gaatttcaga
    37801 gcacaagatc cacaccactg gcgcggcgct catcgcataa ccggcaatac acatcatcgt
    37861 catgccaaca gagagccagg acaagccact ggaagccgta ccgttatcaa actgcatcag
    37921 gcagtaaccc agcaccagag tgcctaacgc catcacgctg aaaccaattt tcagcgccgg
    37981 cttacgccct gctttatcta ccgtaaagac cgcaatgaag gtagcgaaca taaaggtcag
    38041 ccccacgacc agagtcgcaa tcatctgttg ttctgtggtc gtaaagcccg ccattttgaa
    38101 gatacgtggc gcgtagtaca tgatgatgtt cataccggta aactgctgca tcgcctgcaa
    38161 caacataccg agaaatacag cacgacggac gttacggttg atcttaaaca gtgcccaacc
    38221 gccctgtttt aacttcaggc tttcgcgaat ttcgttgagt tcttctcgcg ctttttccga
    38281 cgtatcgcgc agcatacgca atacttcttc cgcctcaata tgacgcccct tttccgccag
    38341 ccagcgcggg ctatttggca ggaagaccac cagaataatc agcagaactg ctggtaaagc
    38401 aagaaccccc aacattgcgc gccagttacc gctataactg aacgctgtat cggataaaaa
    38461 cgccagcacg atgccgagag tgaccatcaa ctggtacatg ctgatcatct taccgcgaac
    38521 gttttcactt gccatttcag aaagatatag aggagcggtg taagacgcga tcccgacagc
    38581 aatgcccaac accacacgag cggcgattaa catctctacg ctggtcgcaa aagcggaccc
    38641 tatcgaaccg agtacaaaca ggatggcccc cgccatcagg ctgtatttac gccccaggcg
    38701 gaacgacagc caaccattaa acagcgcacc aattgctgca ccgagcatca tgctactgac
    38761 cacccattcc tgcaaacgac tggtcagcac aaagtgatcg gtaatgaacg gcaacgctcc
    38821 ggcgattacg ccgatatcaa gaccaaataa caatcctgcg accgcagcag ctaccgaaac
    38881 aaacatattc atacgccgcg tatcccgcag aggacgtggc gttaaagcag attccgtatt
    38941 gatagtaacc attttttcct gccagcagag agtaagacat agtgaaaaaa tacgtgaaca
    39001 attcacacag gtgtcaggtc ggaaatagca taaatatgga ttaaattgct acgacatgtc
    39061 gttatgtgat ggatattcca attttcaa
//
LOCUS       DAFGPF010000035        38819 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFGPF010000035 DAFGPF010000000
VERSION     DAFGPF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38819
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.035"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..222)
                     /locus_tag="LSX49_002033"
     CDS             complement(<1..222)
                     /locus_tag="LSX49_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H"
                     /protein_id="HBL7168450.1"
                     /translation="MFKPTYLARLQACCNKFELADLLQIKVTFLTNVLYRIRPENQYK
                     KFTIKKKSGGEREIFAPDEKLKDIQQRLSE"
     gene            1301..1477
                     /locus_tag="LSX49_002034"
     CDS             1301..1477
                     /locus_tag="LSX49_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016158417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168451.1"
                     /translation="MKKTFTFSLLAIVFASLLSACVPHHHHRHSDGPRGPAPSGKPMP
                     PSNGGPNHGSHGRY"
     gene            complement(1514..3433)
                     /gene="dhaR"
                     /locus_tag="LSX49_002035"
     CDS             complement(1514..3433)
                     /gene="dhaR"
                     /locus_tag="LSX49_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001467850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase operon
                     transcriptional regulator DhaR"
                     /protein_id="HBL7168452.1"
                     /translation="MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFA
                     SIYRRKKAMLTLGQAALEDAWEYMAPRECALLILDETACILSRNGDPQTLQQLSVLGF
                     NDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQALWNWAFCATPLFDSKGRLTGT
                     IALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVIS
                     WDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFE
                     SQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQT
                     RRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAAL
                     AEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDA
                     RRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNN
                     KLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPE
                     HLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRK
                     MKQHGIDAGQFKRRG"
     gene            3661..4731
                     /gene="dhaK"
                     /locus_tag="LSX49_002036"
     CDS             3661..4731
                     /gene="dhaK"
                     /locus_tag="LSX49_002036"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309732.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBL7168453.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQIDGGEGVLLI
                     IKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRPFSSLDQTVDEMFDTLLENGSYHRTLRLWDYQQGSWQEEPQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            4742..5374
                     /gene="dhaL"
                     /locus_tag="LSX49_002037"
     CDS             4742..5374
                     /gene="dhaL"
                     /locus_tag="LSX49_002037"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase ADP-binding subunit
                     DhaL"
                     /protein_id="HBL7168454.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFGKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQTTQARQSLT
                     LEELYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSCEQNLSVPAALDAASS
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            5385..6803
                     /gene="dhaM"
                     /locus_tag="LSX49_002038"
     CDS             5385..6803
                     /gene="dhaM"
                     /locus_tag="LSX49_002038"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaM"
                     /protein_id="HBL7168455.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDNCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPEIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTEISDTCPPYDEEARSLAV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTL
                     TVEEEQERLRQAIDFTLLDLMTLTAKAETSGLDDIAAIFSGHHTLLDDPELQAAASEL
                     LQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGTPLSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKTQRFNRQG"
     gene            7123..8820
                     /gene="treA"
                     /locus_tag="LSX49_002039"
     CDS             7123..8820
                     /gene="treA"
                     /locus_tag="LSX49_002039"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HBL7168456.1"
                     /translation="MKSPAPSRPQKMALIPACIFLCFAALSVQAEETSVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPK
                     EGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPKPYVVPGGRFREVYYWD
                     SYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELL
                     AQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTP
                     RPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVP
                     VDLNSLMFKMEKILARASKAIGDNAMANQYETLANARQKGIEKYLWNDQQSWYADYDL
                     KSHKVRNQLTAAALFPLYVNAAAKDRASKMATATKTHLLQPGGLNTTSVKSGQQWDAP
                     NGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGG
                     GGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPLSESTTQPLKQKEAEPTP"
     gene            9150..10172
                     /locus_tag="LSX49_002040"
     CDS             9150..10172
                     /locus_tag="LSX49_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HBL7168457.1"
                     /translation="MSLTRRRFTQILASTLFLHHLPSFAQSVKFWASLTLPEAQHITR
                     IVSAGAPADLLLLAVAPEKMVGFSSFDFARQALIPLPEHIRQFPRLGRLAGRASTLSL
                     EGLMALHPDLVVDCGNTDETWISQARQVSEQTQIPWLLLNGKLEQSAEQLTTLGKTLG
                     EEHRAAEQANLASRFVGEAQAFATSPAANLSFYAARGPRGLETGLQGSLHTEAAELLG
                     LHNVAQIADRHGLTQVSMENLLRWQPDIILVQEAVTADFIRRDPLWQGVKAVAEQRIL
                     FLSGLPFGWLDAPPGINRLLGLRRLHAWLDPAINRQFKSDMQHYAQLFWHCSLSDADY
                     QKLVAS"
     gene            10172..11152
                     /locus_tag="LSX49_002041"
     CDS             10172..11152
                     /locus_tag="LSX49_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL7168458.1"
                     /translation="MRTVNGCILLLAAISITFAAVSGAYHLDMQQLLALILRQENVPV
                     QEQIVFWQIRVPRILAALFLGAALAGAGTTYQGMFRNPLVSPDILGVSAGAGLGACAA
                     ILWGLSIVYIQLYAFCGGLMVVAGVWLITRRVTRHDPILTLVLVGIALGTLCGAGISL
                     IKTLADPYTQLPSITFWLLGGLSTVTLRDLCYAAPIILIGSLPLFFLRWRMNLLTLSD
                     DEARSLGLNVTRLRFGLIVCATLITASTVAIAGIIGWVGLVVPHIARLLTGHNHQQLL
                     PMAMCTGAILLLLTDTLARSIGTTEIPLGILTAFVGAPFFLFLLLRGGRQ"
     gene            11149..11907
                     /locus_tag="LSX49_002042"
     CDS             11149..11907
                     /locus_tag="LSX49_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7168459.1"
                     /translation="MTLLAVRHASLGYSRHPVLRDVSFTLSQGTICCLLGANGCGKTT
                     LMRSILGVIPLLKGEILLDSLPVQTLSHRQRAQAIAWVPQAHDGIFAFSVLDMVLMGL
                     APTIGAFSVPGKQERLKATEQLEKLGILHLATRRWNTLSGGERQLALIARALVQQPRL
                     LLLDEPASSLDFGHQIQLLDTLAQLKNNGMTMLMSTHHPLHANAIADSIIQVEPDGRV
                     TQGLPTEQLTTKKLAALYRVSADQIHHHLSAIKH"
     gene            11917..12729
                     /locus_tag="LSX49_002043"
     CDS             11917..12729
                     /locus_tag="LSX49_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL7168460.1"
                     /translation="MLIDDIDFADLYLQQLRLAHRTEKTPDHWDQRAEKMAENCASPT
                     DSYLQQLTSKIDLQGAQTLFDMGCGPGTVSLALADKLTTIYGVDYSQGMLNVAARRAA
                     ALKADNVHWIQRAWEEDWSDLPRCDIAVASRSTLVADMRQAMSKLNNQARLRVYTTHL
                     VSTSFVSPAIQRAAGREVIELPNYIFALNVLYQMGIYAHVDFIRGQNCQQDNSTWERF
                     EQNVSWSLGALNDDERERLYRWYQQQDARALAPASRDWALIWWDSVPQETLR"
     gene            12726..13580
                     /locus_tag="LSX49_002044"
     CDS             12726..13580
                     /locus_tag="LSX49_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ModD protein"
                     /protein_id="HBL7168461.1"
                     /translation="MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGG
                     CISGISVACKMLTTLGLTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEW
                     SCGVSDYLAQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETI
                     LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKF
                     SPQQATEIAQIAPSLAPHCTLALTGGINLTTLKNYLDCGIRLFITSAPYYATPADIKV
                     SLQPAASI"
     gene            13606..15576
                     /locus_tag="LSX49_002045"
     CDS             13606..15576
                     /locus_tag="LSX49_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBL7168462.1"
                     /translation="MRLKKRYLCTALSLAFTQQAVAAQESDTLTVWSSPVSSTTTTVL
                     DQPTMKALDKQNVAQALSVVPGVVLQKSGSRNEEQVKVRGFDSRQVPVYFDGVPIYVP
                     YDGNLDLARILTNNLGAVEVSKGYSSLLQGPNQMGGAINITTQKPTKPLEASLGYRQG
                     WSRSQDNAYDMHASFAASSDLGYLQVSGSQLKQDFLGLPHGVNNDIAGKHGKMINSSA
                     DDKRGIVKLGFTPRENDEYTLTYIKQDGEKDNPPYSGNSGQKSRYWQWPEYDKESFYY
                     QGTTQLNDRFTLKSRLYRDTFENTLMMYNSLADLKNKKGSYSHYSDYSDGAGLQLAAD
                     VRENDLLSFAVNWKDDVHREKGAPHAAYDRYEDRTWSLASEYQWAAADNVDVVAGISY
                     DWRDSVEAKKHEKDGSITHYDDNNQSAFNWQVMGKYHFANEDTLALSYYDRTRFPTLK
                     ERYTTSKPAYNQIAIVNPQLKPERARGVDLTWNGAFTHDWGFEVSVYYNRVSDAILSH
                     NIDADTIQNQNSGTVDYSGLDAGIKGKISNILDVGLSYALIHADAKRKDIGKITDLPT
                     QTMTAWMTLKPWEPLSVTLSEEARSSSYSNSDGSQKAAGFAVTHIRADYTLGHGFSVN
                     ASVNNLFDTKYAYSEGFIEEGRNFWAGIEYTF"
     gene            complement(15626..15880)
                     /locus_tag="LSX49_002046"
     CDS             complement(15626..15880)
                     /locus_tag="LSX49_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL7168463.1"
                     /translation="MGIIAWIIFGLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAILVLGVFRLLRRE"
     gene            16081..16815
                     /locus_tag="LSX49_002047"
     CDS             16081..16815
                     /locus_tag="LSX49_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HBL7168464.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLNKAAIPLRISWNGGQLISKIL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRITAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AELHEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREARKKADNVRD"
     gene            complement(16817..17428)
                     /gene="emtA"
                     /locus_tag="LSX49_002048"
     CDS             complement(16817..17428)
                     /gene="emtA"
                     /locus_tag="LSX49_002048"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309714.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HBL7168465.1"
                     /translation="MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQIKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM"
     gene            17528..18442
                     /gene="ldcA"
                     /locus_tag="LSX49_002049"
     CDS             17528..18442
                     /gene="ldcA"
                     /locus_tag="LSX49_002049"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HBL7168466.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIQRLTDAGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAQGNVITFSGPMLVANFGADELNAFTEHHFWLALRNKTFTIEWQ
                     GEGPTCQTEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAHAILNNTEEGTQLTISGHPVLKM"
     gene            18537..20273
                     /locus_tag="LSX49_002050"
     CDS             18537..20273
                     /locus_tag="LSX49_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBL7168467.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIAL
                     PAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            complement(20330..21400)
                     /gene="dadX"
                     /locus_tag="LSX49_002051"
     CDS             complement(20330..21400)
                     /gene="dadX"
                     /locus_tag="LSX49_002051"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309712.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HBL7168468.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIE
                     RIWSALGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISSAMARIEQAAEGLECRRSLSNSAATLWHQEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(21410..22708)
                     /gene="dadA"
                     /locus_tag="LSX49_002052"
     CDS             complement(21410..22708)
                     /gene="dadA"
                     /locus_tag="LSX49_002052"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HBL7168469.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGGKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVDQAAFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEALSVARYSRGFTPSRPGHLHGAHS"
     gene            23038..24570
                     /locus_tag="LSX49_002053"
     CDS             23038..24570
                     /locus_tag="LSX49_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HBL7168470.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSIELLERCPPRMG
                     NL"
     gene            complement(24622..25341)
                     /gene="fadR"
                     /locus_tag="LSX49_002054"
     CDS             complement(24622..25341)
                     /gene="fadR"
                     /locus_tag="LSX49_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HBL7168471.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            25563..27104
                     /gene="nhaB"
                     /locus_tag="LSX49_002055"
     CDS             25563..27104
                     /gene="nhaB"
                     /locus_tag="LSX49_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HBL7168472.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAALLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKV
                     REVLQQFDDQSRNQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTVAGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            27250..27780
                     /gene="dsbB"
                     /locus_tag="LSX49_002056"
     CDS             27250..27780
                     /gene="dsbB"
                     /locus_tag="LSX49_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HBL7168473.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMARFPEWLPLDKWVPQVFVASGDCAERQWEFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(27825..29093)
                     /gene="umuC"
                     /locus_tag="LSX49_002057"
     CDS             complement(27825..29093)
                     /gene="umuC"
                     /locus_tag="LSX49_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V catalytic protein"
                     /protein_id="HBL7168474.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVHNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDEVWGIGRRISKKLDAMGIKTVLDLADSDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFAFNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFA
                     GQGIQQQWQMKRAMLSPCYTTRSSDLLRVK"
     gene            complement(29093..29512)
                     /locus_tag="LSX49_002058"
     CDS             complement(29093..29512)
                     /locus_tag="LSX49_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HBL7168475.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIIIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            29709..30098
                     /locus_tag="LSX49_002059"
     CDS             29709..30098
                     /locus_tag="LSX49_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin E"
                     /protein_id="HBL7168476.1"
                     /translation="MEAFAQKGILIKVLDDGIKKLCSIAAGVVEGKLIPELKNKLKSV
                     QSFFTTLSNTVKQANKDIDAAKLKLTTEIAAIGEIKTETETARFYVDYDDLMLSLLKE
                     AAQKMINTCNEYQKRHGKKTLFEIPEV"
     gene            complement(30305..30751)
                     /locus_tag="LSX49_002060"
     CDS             complement(30305..30751)
                     /locus_tag="LSX49_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HBL7168477.1"
                     /translation="MSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKGL
                     PAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(30843..31502)
                     /locus_tag="LSX49_002061"
     CDS             complement(30843..31502)
                     /locus_tag="LSX49_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBL7168478.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLGLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKVGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            complement(31574..31867)
                     /locus_tag="LSX49_002062"
     CDS             complement(31574..31867)
                     /locus_tag="LSX49_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HBL7168479.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            32108..32509
                     /locus_tag="LSX49_002063"
     CDS             32108..32509
                     /locus_tag="LSX49_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PPC domain-containing protein"
                     /protein_id="HBL7168480.1"
                     /translation="MKIKGISKAVLLLALLTSTSFAAGKNVNVEFRKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYSLP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            complement(32612..32980)
                     /locus_tag="LSX49_002064"
     CDS             complement(32612..32980)
                     /locus_tag="LSX49_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168481.1"
                     /translation="MNMMRIFYIGLSGVGMMFSSMASGNDAGGLQSPACGVVCDPYIC
                     VSSDGISPELTRKYLGEKAAENLQSLQGYDPSEFTFSNGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQTTTKMLFMCRE"
     gene            33500..34195
                     /gene="minC"
                     /locus_tag="LSX49_002065"
     CDS             33500..34195
                     /gene="minC"
                     /locus_tag="LSX49_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBL7168482.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKSPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            34219..35031
                     /gene="minD"
                     /locus_tag="LSX49_002066"
     CDS             34219..35031
                     /gene="minD"
                     /locus_tag="LSX49_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBL7168483.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            35035..35301
                     /gene="minE"
                     /locus_tag="LSX49_002067"
     CDS             35035..35301
                     /gene="minE"
                     /locus_tag="LSX49_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBL7168484.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(35668..36010)
                     /locus_tag="LSX49_002068"
                     /pseudo
     CDS             complement(35668..36010)
                     /locus_tag="LSX49_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(36045..36164)
                     /locus_tag="LSX49_002069"
     CDS             complement(36045..36164)
                     /locus_tag="LSX49_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBL7168485.1"
                     /translation="MPLSYTGYHHFIMMSLMSGEHNTFALSLQDESPGLVPAG"
     gene            complement(36125..36309)
                     /locus_tag="LSX49_002070"
                     /pseudo
     CDS             complement(36125..36309)
                     /locus_tag="LSX49_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36410..36583
                     /locus_tag="LSX49_002071"
     CDS             36410..36583
                     /locus_tag="LSX49_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168486.1"
                     /translation="MSYFSFEIILIPVKNIIPIITVTLILNYLNNSERSLVKQILIED
                     EIIVCATYLIPDN"
     gene            36585..36929
                     /locus_tag="LSX49_002072"
     CDS             36585..36929
                     /locus_tag="LSX49_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415690.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HBL7168487.1"
                     /translation="MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNG
                     VNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVI
                     GGTGGAILGKMK"
     gene            36933..37268
                     /locus_tag="LSX49_002073"
     CDS             36933..37268
                     /locus_tag="LSX49_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmgD family protein"
                     /protein_id="HBL7168488.1"
                     /translation="MMMKKFALLAGLFVFAPMTWAQDYNIKNGLPSETYITCAEANEM
                     AKTDSAQVAEIVAVMGNASVASRDLKIEQSPELSAKVVEKLNQVCAKDPQMLLITAID
                     DTMRAIGKK"
     gene            complement(37327..38439)
                     /locus_tag="LSX49_002074"
                     /pseudo
     CDS             complement(37327..38439)
                     /locus_tag="LSX49_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001582666.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
BASE COUNT         9793 a         9857 c         9321 g         9848 t
ORIGIN      
        1 ttcagaaagt cgttgttgaa tatctttcag tttttcatca ggagcaaaga tctcccgctc
       61 tcctccagac tttttcttta tagtaaattt tttgtattga ttttctggcc ttattctata
      121 caaaacatta gtcagaaatg taactttaat ctgaagcaaa tcagccagtt caaatttgtt
      181 acaacaagcc tgcagccttg ccagataggt aggtttaaac ataacagtaa attccattat
      241 tgattatgtt aatgcacatg caggtactct tacgcattta acggtgacgc caagatgact
      301 tgacggcagt cagagggcga atactcccga ccttgttaac actgattgcg ataccacaac
      361 caacaaatct acctgcatgt gccgtattaa attagcatag tcatcatata actcaagccc
      421 ccaatcaatt tttttcaaaa tcctcaataa gttatagatg gtttgcgttc tgttcatttc
      481 tggcatcaga gtgatgatta ggcaagttag ctgggaaaat ttatccggag tatatacaaa
      541 gaaagtagtc agcccagttg aatcatctaa acaagaccaa ttaactaatt tatttaaatg
      601 aaaaataatg cttttgagct aaccaattat gcacttaagc taaatttacc gtttttgggg
      661 ctagcccaac atcgagggcg cataagcttt agcccacttt tactttcctg ttttctttag
      721 taacagaagg ttaactatca aatatttttg ttgggctatg tgggctaaca gttttcatat
      781 ttacgtgttt ttttattctt ctccggtttc cgtttcagat accggagtaa acaacagcgt
      841 ataagcccag ggacgtgcat gcttgaggtg tctcagccgt ggcatacgta tcagccatcc
      901 ctccacgctg gtggactttt tgagcattcc agcctcatga aggattctgc cggcagtatc
      961 cttgctgaga ggagtagaac ctacgccctt cgcattacga atgcgagcta actccaaaat
     1021 gagtacgaac atgagtacaa aaaaaatata tcattaaatg tagtataaat ttcaatcaga
     1081 tacagcaaaa attacaattc aacgtctaat tccgctaata ctactctggc ggttaataac
     1141 gagccattat gtgagttgca cgtaatggct tttttacgcc tgctacgcgt cttctttcaa
     1201 ttctgagtta ccaaaactca taatcagact cctgacaata ttaacaatgc agcttttatg
     1261 tgataacaat cacagtgcat taaccgttca agagtttgtc atgaaaaaaa catttacctt
     1321 cagcctgtta gcaattgtct ttgcaagcct gttgagtgct tgtgttcccc accatcatca
     1381 ccgccacagc gatggccctc gtggtcctgc gccctccggt aagccaatgc caccttcaaa
     1441 tggtggacca aatcacggca gtcatggtcg ctattaatta gtaattcata gcgggaaagt
     1501 acatactctc ccgctatcca cggcgcttaa actgccctgc atcaatgcca tgttgcttca
     1561 ttttccgcca cagcgtagtg cggccgattc caagtaaagc cgacatttcc tgaatgcgac
     1621 cgcctgtgac ttgggctgcg ttaataattg cctctttttc aacttccgca aatgacagac
     1681 tggtggaaag gcgggtggcg ctgacatcat ctgtcgcctg ctcggtaaac agatgttccg
     1741 gcaaatcact gacgcgaatg cgcccattat cactactcag agcaagattc tcgatgacgc
     1801 tgtaaagttc aaaatcgttg ccaggccatg cacaggaaac caggcgagcg agggcatcgt
     1861 catcaatttt cagccgcgta gagaagcgtt tttcaaggct gcgtaatttg ttattcacca
     1921 gcgccggaat gctgccacgc cgcatacgca gtggcgggat ggtaatttca aatgcatgca
     1981 gcgcgtaata cagctggcga ctaaaacgat tttgttccac cagcattgcg aggtccgcgg
     2041 tcgttgtggc aatcactttg acatcaatgg gtattaaacg ccgcgcatcc agtcgcgtga
     2101 taacaccctg cttgataacc tgaagcaaag cagactgtaa ctccaccgcc agatattcaa
     2161 tcttttcaag aaacagcgtg ccgccgtgcg ccagttccag ccgactcaga cggccatttt
     2221 cattatccgt gcgatcgcca ccaataaatt cttccgccag cgccgcatca ccatataact
     2281 cacaattgac ggcgatataa ggccccgctg cacgctcgct ttcattatga attgcctgac
     2341 ttagcagtgc cttgcccacg ccctcttctc cacaaagcag gacaggaaag ctactgcgcg
     2401 ccgcctggcg accaaaatga atcaagcggc gggtttgcgg atcgtcctgt ggcatatgag
     2461 cgaaggtatg gctgactttt cctaattgac tggtcattaa ctgccgcatc tgttccacag
     2521 gatggagcaa taaaataaag ctggttccct gcgtttctat tatcggttta agggttatca
     2581 ccgcatcaat aaactgatgc tgactttcaa aggttgcttc tacgtgtttg agcggatgtg
     2641 cctgttttat tgcttgttgc aatacggcgg gtaacgttaa gagttcagtg attgcccttc
     2701 cctgacttgc cgtcgcgtca aggcgcaaga ctcgcgccgc ctgggcgttg ataaattgca
     2761 aattaccctg ctcgtcccag ctaatcacgc catcatccat actttctaac agggcattaa
     2821 gttgatttaa atgacggtta gtttcagcga gcaaactgtc cgtcagcagt aaatttccga
     2881 cctcgcgtgc gattgccaac gtcaacggca aatcagctgc ggtagtttgc tcaaccggac
     2941 acgccagcgc tattgttccc gtcaatcggc ccttgctgtc aaacaacggc gttgcgcaaa
     3001 aggcccagtt ccagagtgcc tgtttgaaat gttgatcggc catcgttttc acggcctgac
     3061 cagagatagc cgctaacgat agcgcacaag taccaataat tccctcggcg caatacgtgc
     3121 cgtcattgaa tcccagtaca cttagctgct gcaaggtttg cggatcgcca ttacggctga
     3181 gaatgcaggc ggtttcatcg aggataagca acgcacactc tcgcggtgcc atatattccc
     3241 aggcatcttc cagcgcagcc tgcccgagcg tcagcatcgc tttcttacgc cgataaatag
     3301 aagcaaatgt cacgccctgg gcctggtgtg gtacgttcca tgtctcccgt ttcatcagct
     3361 tattgcatct ctcccaggag gttgcaatta agggagatat gccccgacca tcgttgttaa
     3421 aagcgccact catatcccgc atcccttatg acaaaaggtg ttccggctcg caattttaag
     3481 tattaataca cgtaaaagtt tcaatatgga acactcatta aagcatatgt ttcactatga
     3541 aacataattt gggctaattt tcttttccct tgcctgatgc acaatggatt catcggcagt
     3601 cagtggtcgc cgtgtcgttg aacatcatcc atgccctacc gtaattgctg gagcaaaata
     3661 atgaaaaaat tgatcaatga tgtgcaagac gtactggacg aacaactggc aggactagcg
     3721 aaagcgcatc catcgctgac actgcatcag gatccggtgt atgtcacccg agctgatgcc
     3781 cccgttgcag gaaaagtcgc cctgctgtcg ggtggcggca gcggacacga gccgatgcat
     3841 tgtggttata tcggtcaggg gatgctttcg ggggcctgtc cgggcgaaat tttcacctca
     3901 ccgacgcccg ataaaatctt tgaatgcgcc atgcaaattg atggcggcga aggtgtactg
     3961 ttgattatca aaaattacac cggcgatatt cttaacttcg aaacagcaac cgagttactg
     4021 cacgatagcg gcgtaaaagt gaccactgtg gtcattgatg acgacgttgc agtaaaagac
     4081 agtctttata ccgccgggcg acgcggcgtt gccaacaccg tattaattga aaaactcgta
     4141 ggtgcagcgg cggagcgtgg cgactcactg gacgcctgtg cggaactggg gcgtaagttg
     4201 aataatcaag gccactcaat aggtatcgct ctcggtgcct gtaccgttcc tgccgcgggc
     4261 aaaccttctt ttaccctggc ggataatgag atggagtttg gcgtcggcat tcatggtgag
     4321 ccaggtattg accgccgccc cttctcttcc cttgatcaaa ccgtcgatga aatgttcgac
     4381 accctgctgg aaaatggctc ataccatcgc actttgcgtt tatgggatta tcaacaaggc
     4441 agctggcagg aagaaccaca aaccaaacaa ccgctccagt ctggcgatcg ggtgattgcg
     4501 ctggttaaca atcttggcgc aactccgctt tctgagctgt acggcgtcta taaccgcctg
     4561 accacacgtt gccagcaagc gggattgact atcgaacgta atttaattgg cgcgtactgc
     4621 acctcactgg atatgaccgg tttctcaatc accttactga aagttgatga cgaaacgctg
     4681 gcactctggg acgccccggt ccacaccccg gcccttaact ggggtaaata aggagaaagc
     4741 aatgtcactg agcagaactc aaattgttaa ctggctcact cgttgtggcg atattttcag
     4801 caccgagagc gagtatctta ctggactgga tcgcgagatt ggcgacgctg accacgggct
     4861 aaatatgaac cgaggctttg gcaaagtggt ggaaaaactc cctgctatcg cagataaaga
     4921 tatcggtttc attctcaaga ataccggcat gacgctactt tccagcgtcg gaggtgccag
     4981 tggtccgctg ttcggtacct tctttatccg cgccgcacag acaacccagg cacggcaaag
     5041 cctgacgctg gaagagcttt atcagatgtt ccgcgatggc gcggacggcg taatcagtcg
     5101 cgggaaagcc gaacctggcg ataaaaccat gtgtgatgtg tgggtgccgg tggtggaatc
     5161 gttacgtcag tcctgcgagc aaaatctctc tgttccggcg gcgctcgacg ctgccagtag
     5221 catcgccgaa tccgctgcac aaagtacgat tacgatgcaa gcccgcaaag gccgcgccag
     5281 ttatctcggt gaacgcagta ttggtcacca ggatcccggc gcgacctcgg tgatgtttat
     5341 gatgcaaatg ttggcgttag ccgcaaaaga gtaaggaatt ggtgatggta aacctggtca
     5401 tagtttcaca tagcagccga ctgggagaag gtgtcggtga attagcccgt cagatgttaa
     5461 tgagtgataa ttgtaaaatc gccattgccg cgggaattga cgatccacaa aatcccattg
     5521 gtaccgatgc cgtcaaagtg atggaggcca tcgaatctgt tgccgatgcc gaccatgtgc
     5581 tggtcatgat ggatatgggt agcgcattat tgagtgctga aactgcgctg gaattgctgg
     5641 ctcccgagat cgccgcaaaa gtacgtttgt gtgctgcgcc gttggtcgaa ggtacactgg
     5701 cagcaacggt cagcgcggcc tcgggggcgg atatcgacaa agttatcttt gacgccatgc
     5761 atgcgctgga agccaaacgt gaacaactgg gtttaccgtc ctccgacact gaaatctctg
     5821 acacatgtcc tccgtacgat gaagaagccc gttctctggc ggtggtcata aaaaaccgta
     5881 acggcctgca tgtacgtccg gcctcccggc tggtttatac cttatcgaca tttaatgccg
     5941 atatgttgct ggagaaaaac ggcaaatgcg ttacaccgga gagtattaac cagattgcgt
     6001 tactacaagt tcgctataac gatacgctgc gcctgattgc gaaaggacca gaagctgaag
     6061 aggcactgat cgctttccgt cagttggctg aagataactt tggtgaaacg gaggaagttg
     6121 ctccacctac tctgcgtccc gttccgcctg tttcgggtaa agccttttat tatcaacctg
     6181 ttttatgtac ggtacaggca aaatcaaccc tgaccgtgga agaagaacaa gaacgattac
     6241 gccaggccat tgacttcacg ttattagatc tgatgacgtt aacagcgaaa gcagaaacca
     6301 gcgggcttga cgatattgcc gcaatctttt ctggtcacca tacactgtta gatgatccgg
     6361 aactgcaggc ggcggcaagc gaactccttc agcatgaaca ttgcacggcg gaatatgcct
     6421 ggcagcaagt tcttaaagaa cttagccagc aataccaaca gctggatgat gaatatctac
     6481 aggctcgcta tatcgatgtg gacgatcttc tgcatcgcac cctggtccac ctgacccaaa
     6541 cgaaagaaga actcccgcag tttaactcgc caactattct actggcggag aacatttatc
     6601 cctccacagt actgcaactg gatccagcgg ttgtaaaagg tatctgcctt agcgccggaa
     6661 ctccgctatc ccacagtgcc ctaatcgccc gtgaactggg aattggctgg atttgccagc
     6721 agggtgagaa actgtatgcg atacaaccag aagaaacgct aacgctggac gttaaaacgc
     6781 aacgtttcaa ccgtcagggt taaaccaccg ttcggatggc atcattctga tgtcatccgg
     6841 caatttactc tgcactgatg ttttttaact acctgttata tttttcacca aattatgatg
     6901 atttttcttc gctaatcgcg aacccaacgt cgctggctga cgaataaaca gatgttattt
     6961 tatcactcta tttcgccgtt atttatccct ttaattccct tttctaaaat gtctgtcagt
     7021 tcgcagaatg tgatttcgat catgcagcta gtgcgatcct gaactaaggt tttctgatac
     7081 ttgaataccg ttttattcgg tttcgccaaa ggagaatgat tgatgaaatc ccccgcacct
     7141 tctcgcccgc aaaaaatggc gttaattcca gcctgcatct ttttgtgttt cgctgcgcta
     7201 tcggtgcagg cagaagaaac atcggtaaca ccacaaccgc ctgatatttt attagggccg
     7261 ctgtttaatg atgtgcaaaa cgccaaactt tttccggacc aaaaaacctt tgccgatgcc
     7321 gtgccgaaca gcgatccgct gatgatcctt gctgattatc ggatgcagca aaaccagagc
     7381 ggatttgatc tacgccattt cgttaacgtc aatttcaccc tgccgaaaga gggcgagaaa
     7441 tatgttccgc cagaggggca atcactgcgc gaacatattg acggactttg gccggtatta
     7501 acgcgttcta ccgaaaacac cgaaaaatgg gattctctat taccgctgcc aaagccttat
     7561 gtcgtgccag gcggacgttt tcgcgaggta tattactggg acagttactt caccatgtta
     7621 ggacttgccg aaagcggtca ctgggataaa gtcgcggata tggtggccaa ttttgctcat
     7681 gaaatagaca cttacggtca tattcccaac ggcaaccgca gttactattt aagccgctcg
     7741 caaccgccct tctttgccct gatggtagag ttactggcgc agcatgaagg cgacgccgcg
     7801 ttgaaacaat acctgccgca aatgcaaaaa gaatatgctt actggatgga cggtgttgaa
     7861 aacctgcaag ccggacaaca ggaaaaacgc gttgtaaaac ttcaggatgg tacccttctc
     7921 aaccgctact gggacgatcg cgatacgcca cgaccagagt catgggtgga agatattgcc
     7981 actgccaaaa gcaatccgaa tcgacctgcc actgaaattt accgcgacct gcgctctgcc
     8041 gctgcgtctg gctgggattt cagctcgcgc tggatggaca atccgcagca gttaaacacc
     8101 ttacgcacca ccagcatcgt accggtcgat ctgaacagct tgatgttcaa aatggaaaaa
     8161 atcctcgccc gcgccagcaa agctatcgga gataacgcga tggcaaacca gtacgaaacg
     8221 ctggcaaatg cccgtcaaaa agggatcgaa aaatacctgt ggaacgatca acaaagctgg
     8281 tatgccgatt acgacctgaa aagtcataaa gtgcgcaatc agttaaccgc ggccgccctg
     8341 ttcccgctgt acgtcaatgc ggcagcgaaa gatcgcgcca gcaaaatggc gacggcgacg
     8401 aaaacacatc tgctgcaacc aggcggcctg aacaccacgt cggtgaaaag tgggcaacaa
     8461 tgggatgcgc caaacggctg ggcgccgttg cagtgggtcg cgacagaagg attacaaaac
     8521 tacgggcaaa aagaggtagc gatggacatt agctggcact tcctgaccaa tgttcagcac
     8581 acctatgacc gggagaaaaa gctggtggaa aaatatgatg tcagcaccac cggaacaggg
     8641 ggcggcggtg gcgaatatcc attacaggat ggctttggct ggaccaatgg cgtgacgctg
     8701 aaaatgctgg atttgatctg cccgaaagag caaccgtgtg acaatgttcc ggcgacgcgt
     8761 ccactcagtg aatcaacaac acagccgcta aaacaaaaag aggcggaacc tacgccttaa
     8821 ctttactgta tatcgagcaa tgccattacg tgcataaaat tggcattgct ctttcttcat
     8881 cacgaaatac cactctttct acggtctatg cctttatttt cttttattag agaagatttt
     8941 aattttattt tatcaacttg ttaatcatca cacctctatt tatattttcc cccactcccc
     9001 attctccctg acaattttct tgtggaacaa agtgttattt aagaaacaag caaatcattc
     9061 tgtctcttta gacaaatttt gacatcaaac atgatctttt tcgctatatg tgtaagtata
     9121 tagcggtttt aattatcagg atattactta tgtcactaac cagacggagg tttacacaga
     9181 ttcttgcgtc gacattgttc ctgcatcatc tgccgtcctt tgcacaatca gtcaaattct
     9241 gggcctcact gacgcttccc gaagcccaac acattacacg catcgtcagc gcaggcgcgc
     9301 ccgccgattt actattgctg gctgtcgcgc cagaaaaaat ggtcggtttt tcctcttttg
     9361 attttgcccg tcaggcatta attccattgc cagagcacat tcgccagttc cccaggctgg
     9421 gacgactcgc cgggcgcgcc agcacactct cgctggaagg gcttatggcg ttacatcccg
     9481 atttggtcgt tgattgcggc aatacggatg aaacctggat ctcccaggca cggcaggtta
     9541 gcgaacagac acaaataccc tggttattgc ttaacgggaa actggaacaa tcagcagaac
     9601 agttaacaac gcttggcaaa acgttaggcg aagagcaccg cgccgcagaa caagccaatc
     9661 tcgccagccg cttcgttggt gaagctcagg cattcgccac ctcacccgcc gctaatctca
     9721 gcttttatgc tgcgcgcggt cctcgagggc tggaaacggg cttacagggt tcgttgcata
     9781 ccgaggcggc ggaattatta ggtttgcaca acgtcgcgca aatagccgat cgccacggtc
     9841 tgacacaggt ttccatggaa aatctcctgc gctggcagcc ggatattatt ctggttcagg
     9901 aggccgttac tgcagatttt attcgtcgtg atcctctctg gcagggcgtg aaagcggttg
     9961 cggaacaacg catcttattt ttaagtggcc tgccctttgg ctggctggat gccccgccgg
    10021 gaatcaaccg tcttctggga ttacgcagac ttcacgcctg gctggatccc gccatcaatc
    10081 gccagtttaa aagtgacatg cagcattacg cccaactgtt ctggcattgt tcactcagtg
    10141 acgccgacta tcaaaaattg gtggcgagct aatgagaacc gtaaacggat gtattttgct
    10201 gctggcagct atcagtatca cttttgccgc cgtaagtggg gcttatcatc tcgatatgca
    10261 gcaactgctg gcgctcattc ttcgtcaaga aaatgttcct gtgcaggaac aaattgtctt
    10321 ctggcaaatc cgcgtgccgc gtattcttgc tgcgctgttt ctgggcgcgg cgctggcagg
    10381 ggccggaacc acctatcagg gaatgttccg taatccctta gtgtcaccgg atattttagg
    10441 cgtctccgcc ggtgccggac ttggtgcctg cgcggcaatc ctgtggggat tatccattgt
    10501 ttacatccag ctgtacgcat tttgcggcgg gctgatggtg gtcgcgggcg tctggttgat
    10561 tacgcgtcgg gtgacccgcc acgatccgat cttaaccctg gtgctggtag gcattgcgtt
    10621 aggaacgttg tgcggagcgg ggatatcgct aataaaaacg ctggccgatc cttacaccca
    10681 gttaccgtca attaccttct ggttgctggg ggggctgtcc accgtgacct tacgcgatct
    10741 ctgctatgct gcaccgatca ttctcatagg ctccttgccc ctgttttttc tccgctggcg
    10801 catgaattta ctcacgcttt ccgacgacga agcccgttcg ctgggactga acgtgacacg
    10861 tctgcgcttt ggattgattg tctgcgccac actcatcacc gccagcacgg tagcaatagc
    10921 aggcataatt ggttgggtcg gcctggtcgt tccgcacatt gcccgcttgt tgaccggtca
    10981 taaccatcag cagctgttgc ccatggcaat gtgtactggc gcgattctgc tcctgcttac
    11041 cgatacgctg gcacgcagca ttggaacaac agaaatccca cttggcattc tgaccgcttt
    11101 tgttggtgca ccgtttttcc tgtttttgtt gttacgcgga ggtcgccagt gactttgctt
    11161 gccgtccgtc atgcgtctct gggttactcc cgccatccgg tgctacgcga cgtgtccttc
    11221 accctgtcgc aaggaacaat ttgttgtctg ttaggagcca atggttgcgg caaaaccaca
    11281 ctcatgcgct ccattcttgg cgttataccg ttattaaaag gcgagatctt actggatagc
    11341 ctccctgtgc agacactcag ccatcgccag cgcgcgcagg ctattgcctg ggtgccgcag
    11401 gcgcacgacg gcatttttgc ttttagtgtg ctggatatgg tgttgatggg cctggccccc
    11461 accataggcg ctttttccgt tcccggtaag caagaacgcc tgaaagcaac ggagcaactg
    11521 gaaaagctgg gcattttgca tctggcgaca cgacgctgga atacgcttag cggcggtgaa
    11581 cgtcagctgg ctttaatcgc ccgtgcactc gtccagcaac cgcgcttgtt attactggat
    11641 gagcctgcct ccagcctcga tttcggtcat cagatccaac ttctggacac gctggcgcag
    11701 ctcaaaaata acggcatgac aatgttaatg tcgactcatc atccgctcca tgcaaacgcc
    11761 attgccgaca gcattatcca ggtagagcca gatggacgag taacacaagg cttaccgacc
    11821 gaacagttaa caacgaaaaa actggctgcc ctgtaccggg tttctgccga ccagattcac
    11881 catcacctct ctgcaattaa gcactaagga aaaatcatgc tcattgacga tattgatttt
    11941 gcagaccttt accttcagca actcaggctg gcccatcgca cagaaaaaac gccggatcac
    12001 tgggatcaac gggcggaaaa aatggcggaa aattgcgcct cgcctacgga cagctacctg
    12061 caacaactga cctcaaaaat tgacctgcaa ggcgcgcaaa ccttattcga tatgggctgc
    12121 ggaccgggta ccgtatcgct ggcgctggcg gacaaactca cgacgattta tggcgttgat
    12181 tacagtcagg ggatgctgaa cgttgccgcc cgtcgtgccg ccgcgctaaa ggcagacaat
    12241 gtccactgga tccagcgcgc ctgggaagag gactggagtg acctgccacg ctgcgatatt
    12301 gccgtggctt cccgctccac tctggtggct gatatgcgcc aggcaatgag caaactgaat
    12361 aatcaggcac ggcttcgcgt ctatacgact catctggtca gcacctcgtt cgtctctcca
    12421 gccattcagc gggcggctgg tcgggaagtg atcgaattac ccaactatat ctttgcactc
    12481 aacgtcctgt atcagatggg aatttatgct cacgttgatt ttatccgcgg acaaaattgc
    12541 caacaggata acagcacctg ggaacgtttt gagcagaacg tcagctggag tctgggcgcg
    12601 cttaacgacg atgagcgtga gcggttatat cgctggtatc aacaacaaga tgctcgtgcc
    12661 ctcgcccctg ccagccgcga ctgggcgctc atctggtggg atagcgtacc gcaggagaca
    12721 ctgcgatgat tttcctttct caggcacaaa tcgatgcgtt attgctggaa gatatccagg
    12781 gcggtgacct gaccacgcga gcattaaata ttggacacca gcatggctat atagagtttt
    12841 ttctccgtca gggcggctgc atcagcggca tttctgtcgc gtgtaagatg ttaactacgc
    12901 tgggattaac tattgatgac gcggtcagcg acggttcaca agcgaacgcg ggtcagcggc
    12961 taatccgtgc gcaaggtaat gccgcagcac ttcatcaggg atggaaggca gtccagaatg
    13021 tgctggagtg gagttgcggt gtttctgatt atctcgctca aatgctggcg ttacttcgtg
    13081 aacgttaccc tgatggcaat atcgcctgca cccgaaaagc aattccgggc acccgcttac
    13141 tggcctcgca ggcaattctg gctgccggag gactgattca tcgtgccgga tgtgcggaaa
    13201 ccatattatt gtttgccaac caccgccatt ttcttcatga caatcaggac tggtcaggcg
    13261 caatcaatca gttacgtcgc cacgcacccg agaagaaaat agttgttgaa gccgacacgc
    13321 cgaaagaggc aatcgccgcg ttacgcgcgc aaccagacgt acttcagctc gacaaattta
    13381 gtccgcaaca ggcaactgaa attgcgcaaa tagcaccgtc gctggctccc cactgcacgc
    13441 tggctctgac cggcggaatt aatctgacaa cactcaaaaa ttacctcgac tgcggcattc
    13501 gcctttttat tacctccgcg ccttattacg cgacaccagc tgacattaaa gtcagtctgc
    13561 aacccgcagc ctctatttaa ttctttgtta aacggaattt attctatgag actcaaaaaa
    13621 cgttatctct gcacagcatt atcacttgcc tttacccagc aggccgtagc ggctcaggag
    13681 agtgacacgc tgaccgtatg gtccagtccg gtatcatcaa cgacgaccac cgttctcgat
    13741 caacccacca tgaaggccct ggataaacag aatgtcgctc aggcattaag tgtcgtcccc
    13801 ggcgtggtgc tgcaaaagtc aggtagccgc aacgaagaac aggtcaaagt tcgtggcttt
    13861 gatagtcgtc aggtgccggt ctatttcgac ggtgtgccca tttatgttcc ctatgacggc
    13921 aacctcgatc tggcgcggat tctgaccaac aatttggggg cagttgaagt ttccaaaggg
    13981 tattcgtcgc tgcttcaggg gcctaatcag atgggcggag ccattaatat caccacccag
    14041 aagccaacaa aacctctgga agcaagtctg ggatatcgcc agggatggag ccgtagccag
    14101 gacaatgcct acgatatgca tgcttcattt gccgccagca gcgatctggg gtatttgcaa
    14161 gtcagcggta gccagctaaa gcaggatttt ctcggcctgc cgcatggtgt aaataatgat
    14221 attgcaggca aacacggcaa gatgattaat tcatcggctg atgataaacg cggcattgtg
    14281 aagctcggtt ttacaccacg cgaaaacgat gaatacacat tgacttacat taagcaggat
    14341 ggtgaaaaag ataacccgcc atacagtgga aatagtggtc agaaatcacg ctactggcag
    14401 tggccagagt atgacaaaga aagtttttat tatcagggaa cgacccaact aaacgatcgt
    14461 tttaccctga aaagtcggct gtatcgcgac acctttgaaa atacgctaat gatgtacaac
    14521 tcgctggctg atttgaaaaa taaaaaaggc agctacagcc attattccga ttacagcgac
    14581 ggtgccgggt tacaactggc agccgatgtg cgtgaaaacg atctgctgtc gtttgccgtt
    14641 aactggaaag atgacgtaca ccgggaaaaa ggtgcgccgc acgccgctta cgatcgctat
    14701 gaagatcgta cctggtcgct cgccagtgaa tatcaatggg ctgctgccga taatgtcgat
    14761 gtcgtggctg gaatcagcta tgactggcgc gatagcgtag aagcgaaaaa acatgagaaa
    14821 gatggcagta tcacccatta tgacgacaac aatcagtcag cttttaactg gcaggtgatg
    14881 gggaaatacc actttgccaa tgaagacacg ctggcgcttt cgtactatga ccgcacacgc
    14941 tttccgacgc tgaaagaacg ctataccacg tccaaacctg cgtataacca gatagcgatt
    15001 gttaacccgc agctcaagcc ggaacgcgcg cgcggggtgg atttaacctg gaatggtgcc
    15061 ttcacgcacg actggggatt tgaggtcagc gtttactata accgggtgag tgatgccatc
    15121 ctctcgcaca atatcgatgc cgataccatt caaaatcaga acagcggcac ggtggattac
    15181 agcggtctgg atgccggtat taaggggaaa atcagcaata tactggatgt aggattgagc
    15241 tacgccctga tccacgctga tgccaaacgc aaagacatcg gcaagataac cgatctgcca
    15301 acgcagacaa tgaccgcatg gatgactctc aaaccgtggg agccgttaag cgtaacgctg
    15361 tcggaagagg cgcgttcctc cagctacagc aacagtgacg gttcacaaaa agccgccggt
    15421 tttgcggtga ctcacattcg agccgattac accttaggtc atggcttcag cgttaatgcg
    15481 tcggtcaata acctgtttga taccaaatat gcctacagtg aagggtttat tgaagaaggt
    15541 cgcaatttct gggcaggtat cgagtatacg ttctgatgtg aaagcggata gcggcatctg
    15601 tatcgctatc cgccttatga aaatcttatt ctcttcgcag gaggcggaat acgcccagca
    15661 ccaggatagc gcccaccacc gccaccagga agctgtgcaa attaaaaccg ctgatggagc
    15721 cgccaatgcc aaacatggtc gccagccagc cgccgaccac cgcaccgact atcccaagaa
    15781 tacaggtcag gaaaaatcca ccaccatctc gccccggcat gattagcttg gcgataatgc
    15841 cggctatcag gccaaaaata atccaggcaa taattcccat gttcaggccc tcgtttcgat
    15901 gaatcggacg caagaaatgc ttacgtcaac gctctaagta taggcaaggg cgggatcgat
    15961 gctgggcata tgtcggctga tttaagaaca acatgtaaaa aatattcgcg catttgtatt
    16021 aagttttgtt aactgcgacc gataaaccaa agacagtttg tcagtcagga gtttttccgc
    16081 gtgagtcatt accatgagca gttcctgaaa caaaatccgt tagccgtcct gggcgtgtta
    16141 cgcgatttga acaaagccgc aattcctttg cgtatcagct ggaatggcgg gcagctgatc
    16201 agcaaaatac tggcaataac tccggataaa ctggtgctgg atttcggcag ccaggccgaa
    16261 gacaacatcg ccgtgctaaa ggcgcagcac attaccatta ccgccgaaac tcagggtgcg
    16321 aaagtcgagt ttactgttga acaactacag cagagtgaat acttgcagct tccggcattt
    16381 attaccgtac cgcctcccac cttatggttt gtacaacgac gccgatattt ccgcatcacc
    16441 gccccactcc atccgcctta tttttgccag accaaactgg cggataacag tacgttacgt
    16501 ttccgcctgt atgatttgtc gttaggcggc atgggcgcat tactggaaac agcaaagcct
    16561 gccgaattac acgaaggcat gcgcttcgct cagattgaag tcaacatggg gcaatggggt
    16621 gtttttcact ttgacgccca gttaatctcc atcagcgagc gcaaagtgat tgatggcaaa
    16681 aatgaaacca tcaccactcc ccgtctgagc ttccgttttc ttaacgtcag cccgacggtg
    16741 gagcggcaat tacagcggat tattttctct ctcgagcgag aagcccggaa aaaagcggac
    16801 aatgtgcgtg actgatttac atcgcgtcca gtgcctgctc aagtttgtag atatagcgcg
    16861 gagcctgcgg cgcaggatga tttcgcgcta cgtgatcgag gaactcatca gcatccagat
    16921 cgttgatttt gctgatcgcc tttttccgat ctgacgagaa agtccgtagc agcgcacctg
    16981 ccccgttagc gtatgacacc accagcgcat attgcagtac cttcggatct tcaatgcctg
    17041 ccagcgggcc ggtttccaga atattcaggt aagccgctcc cattgaaata ttacgctccg
    17101 gatttttcag ctcgctggtc gtcggctcac cgctccagcc catacgacga tatacatcac
    17161 gtccggaggt tgaagctttt atctgcatca aaccaatggc attcgattta ctcaccgcgt
    17221 tcggattacc acccgattcg atagcgataa tcgccgtgat caattgtgga tcgacgcccc
    17281 aggctgcacc ggctttctgg cttattggca tccactgcat cgcacgttgc accggaactt
    17341 tcgcgttcca cggcgggttc gtatagtcat gctttgatga acaacccgct aataacacaa
    17401 tcaaaaaggc aaaccatctc aatttcactt cttctatcct tatagcctgg aatcgccgtt
    17461 gaggtgacaa cggcacacct aagcggcatg atatacattt cgtttctgtt gtcagcaagg
    17521 aattgccatg tctctgtttc acttaattgc cccatcgggt tactgcatta aacagcacgc
    17581 cgcgctgcgt ggtatccagc gccttaccga cgcggggcat caggtcaata acgtcgaggt
    17641 tattgcccgt cgttgtgagc gttttgcggg tacggaaacg gagcgtctgg aagatctcaa
    17701 ttctcttgcc agactgacta cccccaacac catcgtgctg gctgtacgcg gcggttacgg
    17761 tgccagtcgt ttactggcag atattgactg gcaggcactg gtggctcgcc aacaacatga
    17821 cccgttactc atttgcggac atagcgattt taccgccatt cagtgcggtc ttctggcgca
    17881 aggcaatgtc atcaccttta gcggccccat gctggtagca aactttggcg cggatgaact
    17941 aaatgccttt accgagcacc acttctggct ggcgttacgc aataaaacgt tcaccattga
    18001 atggcaaggg gaaggcccga catgtcagac cgaaggcacg ctgtggggag gcaatcttgc
    18061 gatgctgatt tcactgattg gtacaccgtg gatgccaaaa attgagaacg gtattctggt
    18121 gctggaagat attaacgagc accctttccg cgtcgaacgc atgctgttgc agctctatca
    18181 tgctggaatt ttgccacgtc agaaggcgat tattctcggt agctttagcg gcagcacacc
    18241 taatgattat gacgcaggtt acaacctgga gtcagtgtac gcgtttttgc gttcccgcct
    18301 gtcgattcca ctcattaccg gcctcgattt tggtcatgaa caacgcacgg ttacgctgcc
    18361 gttgggcgca catgccattc tgaataacac cgaggaaggc actcagttga cgattagcgg
    18421 tcatcctgtt cttaaaatgt aaaaaaatca cgcttcaggg ctaagtaaaa cgctgtctct
    18481 gccgctaata tggtagggtt tatatcagag acagcgtaat caggagtaac cgaccgttgg
    18541 atgccacaac aataattagc cttttcatct taggatccat ccttgtcacc agcagtatat
    18601 tacttagttc attttcttcc cgtcttggca ttcctattct ggttattttt ctggcgatcg
    18661 gcatgttggc gggggttgat ggcgtcggcg gtatcccgtt tgataattac cccttcgcct
    18721 acatggtaag taacctggcg ctggcgatta ttttgctcga cggcgggatg cgcactcagg
    18781 ccagttcctt tcgtgtggcg ttaggaccgg cactgtcgct ggcgacgctg ggcgtactta
    18841 tcacctctgg tttaaccggc atgatggcgg cgtggctgtt taatcttgat ttgattgaag
    18901 gattattaat cggcgctatc gtcggctcca ccgatgctgc agcggtcttt tctctgctgg
    18961 gtggtaaggg gcttaacgaa cgtgttggct cgacgctgga aattgaatcc ggcagtaatg
    19021 atccaatggc ggtctttctg acgattactc tgattgcgat gatccagcag catgaaagca
    19081 gtgtcagctg gatgttcgtg gtcgatattc tgcagcaatt tggcctcggg attgtcatcg
    19141 ggcttggcgg tggttattta ctgctgcaaa tgattaatcg catcgccctg cccgccggat
    19201 tatatccatt gctggcatta agcggcggta ttttaatttt tgctttaacc acggcgctgg
    19261 aaggcagcgg tattctggct gtttatctgt gcggttttct gctgggtaat cggccgattc
    19321 gcaaccgcta cggcatcctg caaaatttcg acggcctcgc ctggctggcg caaatcgcca
    19381 tgttcctggt gctggggcta ttggttaacc caagcgatct gctgcctatt gccattccgg
    19441 cgctcatttt gtccgcatgg atgattttct tcgcccgtcc tctttcggta tttgccggat
    19501 tgctaccgtt ccgtggcttc aatctgcgtg agcgcgtgtt tatcagctgg gtaggattac
    19561 gcggcgcggt gccgattatt ctggctgtgt tcccgatgat ggcggggctg gagaatgcgc
    19621 gactgttctt taatgtcgcc ttctttgtgg ttctggtttc actgctattg cagggaacat
    19681 cactctcgtg ggcggcgaaa aaagccaaag tggtcgttcc gccagtggga cgtccggtgt
    19741 cacgcgttgg cctggatatt catccggaaa atccgtggga gcagtttgtt tatcaattga
    19801 gtgccgataa atggtgcgtg ggcgcggcac tgcgtgattt gcatatgcca aaagagacgc
    19861 gtattgcggc actgtttcgt gataaccagt tgcttcatcc caccggcagc acccgactgc
    19921 gcgaaggcga tgtgttgtgt gtaattggtc gggaacgcga tctcccggcg ctcggtaaac
    19981 tgttcagcca gtcgccgccg gtcgcgctgg atcaacgctt ctttggtgac ttcattctcg
    20041 aagccagcgc caaatatgct gatgtggcgc tgatatatgg tctggaagac gggcgagaat
    20101 atcgcgataa gcagcaaacg ctgggtgaaa tcgtccagca gttgttaggc gcggcaccgg
    20161 ttgtcggtga ccaggtagag tttgccggga tgatctggac ggtggccgag aaagaagata
    20221 atgaagtgtt gaagattggt gttcgggtag cggaggaaga agccgaatct taagtttaat
    20281 gtgtttcgta acgctggata cgacgctggt cgcatccagc gataacaagt tacaccgtca
    20341 caaccgggac gcgtaacgcc agcgcgcaca tcaactcata gcctaccgtt ccggcagcgg
    20401 cggcgacatc atcaattttg atctccttgc cccacagctc aactggcgta ccaatacccg
    20461 cttgcgggca aggcgttaaa tcgaccgcca gcatatccat cgagactgtc cccaccgtca
    20521 tggtgcgaac gccgtccact aaaacagggg taccggtagg cgcgtggcgc ggataaccgt
    20581 cggcgtatcc tgcggcgaca atgccgattc gctgttcatc gcgcgcagta tagcgaccgc
    20641 cgtagcccac acgctcgccc gcttttagcg tctggacacc aataatctca ctgcttagcg
    20701 tcatcaccgg acgtaatccg gtattggcga tatcacgcca ctgaccggac ggcgaagcac
    20761 catacaaaat aatgccaggc cgaacccagt caaaatgcgc ttcctggtgc cacagagtcg
    20821 ccgccgaatt agacaacgaa cgccgacact ccagcccttc cgccgcctgc tcaatacgcg
    20881 ccatcgcgct ggaaattcca tcaggatgtt ccgcttcggc aaaatgcgac atcagggtca
    20941 tttcgccaac attcgccatc gcccgcaact gctgccagac ggtaagcacg cgatcgggct
    21001 ggaagcccaa ccgattcatc ccactgttca ctttaagata aatatccaac ggtgctttta
    21061 gccgcgcatt ttgcagtgct ttgagctgcc agttgctgtg tacgcaggtg gtcaggcggt
    21121 gctggtcata aatctccaga tcctgagcat ggaaaaatcc ttccagcatc aggatcggtc
    21181 ctttccagcc gcgctcacgt aacgttattg cctcttccag gttaagcaat gcaaagccat
    21241 cggtagcccc gagcgcgctc cagatacgct caataccgtg cccgtaagcg ttcgctttta
    21301 ccaccgacca gacgcgcgcg tgcggcgcgg cctggcggac aatggacaga ttctgtttta
    21361 atgcctgcag atcgaggctg gcctgtatcg gacgggtcat ctcgtttcct tagctgtgtg
    21421 cgccatgtaa atggcccggg cgtgatggcg taaatccacg gctgtagcgc gctacgctta
    21481 gagcttcata cgggatcgct ggcgtgcgcc ccgagagcag atcgcttaac aactgaccgg
    21541 aaccgcaagc catcgtccag ccgagcgtgc cgtgaccggt attcaaccac agatttttaa
    21601 agcgtgtacg cccgacaacc ggcgtgccgt ctggcgtcat cgggcgcagg ccagtccaga
    21661 aagccgcctg atcaacatga ccgccgcgtg gatagagatc gcgaaccacc atctccagcg
    21721 tttcacgacg cggttgcaac agctcggtgt taaaaccaac aatttccgcc attccgccga
    21781 cacgaatgcg gttatcgaaa cgggtaatgg cgattttgta ggtttcatca agaatagtgg
    21841 ataccggcgc accatcttcc tgcgcaattg gaatggtcag cgagtagcct ttcagcggat
    21901 acaccggaat atcaacaatg cctttgagca tcgccgtcga gtaagaacca aacgccatca
    21961 catacgcatc ggccttaatc acttcatcac cacacttcac gccgtagatt tgctcgccgt
    22021 cgcaaagcag ttggtcaacg ggcgtattaa agcggaattt accccccgcc tgctccgcca
    22081 tccgcgccag attctgggta aacagctggc agtctccggt ttcatcattg ggcagttgca
    22141 ggccgcccgt cagtttgtgc gctacttctg ccaacgcggg ctccacttcc gccaggcggc
    22201 tggattccag cagctgatac ggtacgccag catcttccag cacggcgata tcgcgggtcg
    22261 cgttttcata ctgttgttcg gtacggaaca gttgcagcgt cccaccctga cgcccttcat
    22321 actgaatatt ggtttcggcg cgcaatgctt tcaggcaatc acggctgtat tccgccagac
    22381 gtaccatccg ccctttgttt tccatgtagt ggctggtgtc gcagttacgt aacatttgcc
    22441 acatccattt caactggaac tgcgtaccgt cgagacgaac cgccagcggc gcatggcgct
    22501 ggaacatcca tttaatcgct tttaaaggca cacctggtgc cgcccacggt gcagcatatc
    22561 cgggggagat ttgcccggca ttcgcggcac tggtttccag ggcggccccc ggctcccgat
    22621 caatgacggt gacctcatgt cctgcctgat ttaagtacca ggcgctggca acgcctacca
    22681 caccacttcc cagtatgaca actcgcatag ccactccgat aacggtagat acagtaaaag
    22741 aataataatc taattacatc ttgataactc agttgaaaat attattcaac atacggcttt
    22801 tttatggtga gctggctcac atctccctga ctctgcggca atatggcgtc tttagtatct
    22861 cctgctgaac gcccttttta tccagcataa aattccgttc agaagcggat tagtggcact
    22921 ctgataataa gaaatcgcaa agaaaaaaat tctccggcga cgcggttttt aacaggtgtt
    22981 ctatgcttga aatgaggtgc tccacacaga gagcgccgac aacaatgagg tgcgcgtatg
    23041 gcgacgatcg attctatgaa taaggacacc acacgtttga gcgatggacc cgactggacg
    23101 ttcgacctgc tggatgttta tctggcagag atagaccggg tggcgaaact ctaccggctg
    23161 gatacctacc cgcaccagat tgaagtgata acctcagaac agatgatgga tgcttactcc
    23221 agcgtcggca tgccaattaa ctatccgcac tggtcattcg gtaaaaagtt tatcgagact
    23281 gaacggctgt ataagcacgg tcagcaagga ctggcctatg aaatcgtcat taactctaac
    23341 ccgtgtatcg cttacctgat ggaagagaac accattacca tgcaagcgtt ggtgatggct
    23401 catgcctgct atgggcataa ctctttcttc aaaaacaatt acttattccg tagctggacc
    23461 gacgccagtt cgattgtcga ttatctgatt tttgcccgta aatatattac cgagtgcgaa
    23521 gaacgttatg gcgttgatga agtagaacgg cttctggact cgtgccacgc gctgatgaac
    23581 tacggcgtgg accggtacaa acgcccgcaa aaaatctcgc tgcaagaaga gaaagcccgg
    23641 cagaagagtc gcgaagagta tctgcaaagt caggtcaata tgctctggcg taccctgccg
    23701 aagcgcgagg aagagaaaac ggttgctgaa gcgcgccgct atccgtccga accacaagaa
    23761 aacctgctct attttatgga gaaaaatgcg ccactgctgg aatcatggca gcgtgaaatc
    23821 ctgcgtattg tgcgtaaggt gagccagtat ttttatccgc aaaaacagac tcaggtgatg
    23881 aacgaaggct gggcgacctt ctggcactac accatcctta accatctgta tgatgaaggg
    23941 aaagtaacgg aacgttttat gctggagttt ttgcacagcc acaccaatgt ggtcttccag
    24001 ccgccctata acagcccgtg gtacagcggc atcaacccat atgccctcgg gttcgccatg
    24061 ttccaggata ttaaacggat ttgtcagtcg ccgacggaag aagacaaata ctggttcccg
    24121 gatatcgccg gttccgactg gctggaaacg ctgcatttcg cgatgcgtga tttcaaagat
    24181 gagagtttta tcagccagtt cctgtcaccg aaagtgatgc gtgatttccg cttcttcacc
    24241 gtactggatg atgatcgaca taattatctg gagatttccg ctattcataa tgaagaaggt
    24301 tatcgggaaa tccgtaaccg gttatcgtcg caatataact taagtaatct ggagccgaat
    24361 attcagatct ggaacgtgga tttgcgcggt gaccgttcgc tgacgctgcg ttacattcca
    24421 cataatcgcg caccgttgga tcgggggcgc aaagaagtgc tgaagcatgt gcatcgcctg
    24481 tggggatttg atgtgatgct ggaacagcaa aacgaagacg gcagcatcga gttgctggaa
    24541 cgttgcccgc cgagaatggg aaatctgtaa aaacaacgaa aaacccctcg tttgaggggt
    24601 ttgcttttta aacggaaggg attatcgtcc ctgaatggct aaatcacccg gcagattttt
    24661 ctgcatccgg tgccaaatct cgccactctc atgcccatag cgacgcactg tttcatatac
    24721 ctgatcgtgt gcgccttcac tgcacaacgc cgacagtttg tgatagaagc ccagcgccag
    24781 actgcgcgct tccggattgg cgaaatagtg acgaccaatg cgcgtataca gccctttcat
    24841 cccgttaagg atcagaccgt aaatcgggtt gccggaagca aacgccaggc cgcggaaaat
    24901 gttgtaatcc agctcggcaa aggcgtcggc gtgatcggcc acttcattag cggttgccag
    24961 cacttcctgc gctttatcgg gatgttgacg aaacgcggtg cgaataaaaa tagttgaaat
    25021 attggtacgc accgacagca aattatcaat aagctgcggc acactttcgt ggtccagtcg
    25081 cgccagtgtt tcaaggatat ttaaaccaga ggtttcccag aaattattca ccttcgtcgg
    25141 cttgccgtgt tgaatggtca accagccatc tcgtgccaga cgttgtaaca cttcacgtaa
    25201 cgtagtacgc gttacgccaa ttaattctga aagttcacgt tctgcgggca aaatagtccc
    25261 gggagggaag cggttattcc agatactttc aataatgtac tcttccgcga aacccgccgg
    25321 gctttgcgcc ttaatgacca tagtgagatt tccataacac agcaaaacaa agttggactc
    25381 atcataccag agggctaact acgctgatag aagacaaaaa gaagaaaaaa gggatcaagg
    25441 cttcattttc tgcatctctt tccccttgac tatcaagact tgcctcactc ctgtctgacc
    25501 gttaagcttt gcgtttaaac ataaaaacat cattgattat ttctaaggta agggaaacca
    25561 tcatggagat ctcctggggc cgcgcactat ggcgcaattt tttgggccag tcccccgact
    25621 ggtacaaact cgccctcatc attttcttaa tcgtaaatcc gttaattttc ctcatcagcc
    25681 ctttcgtcgc tggctggttg ctggtagcgg aatttatttt cactctggcg atggccctga
    25741 aatgctaccc gctgctcccc ggtggtctgt tggctatcga agcggtattc atcggcatga
    25801 ccagcgcgga acatgttcgt gaagaagtgg cggcaaatct tgaagtcttg ctgttactga
    25861 tgtttatggt ggcgggtatc tattttatga aacagctgtt gttgttcata tttacccgtt
    25921 tgctgttaag cattcgctcc aaaatgctgc tgtcgctctc tttttgcgtg gcggcggcgc
    25981 tcctctccgc gttcctcgat gccttaaccg tcgtggcggt ggtgatcagc gttgcagtcg
    26041 gtttttatgg tatttatcac cgcgtagcct cttcccgtac tgaagatacc gacctgcaag
    26101 acgatagtca tatcgacaag cattacaaag tggttctgga acagttccgt ggctttctgc
    26161 gtagtctgat gatgcatgcc ggtgtcggca ccgcattagg cggcgtgatg accatggtgg
    26221 gcgaaccaca gaacctgatc atcgctaaag cggctggctg gcattttggc gatttcttcc
    26281 tgcgcatgtc gccggtgacc gtcccggttc tgatttgtgg cctgttaacc tgcctgctgg
    26341 tagagaagct gcgttggttt ggctacggtg aaacgctgcc ggagaaagtc cgcgaagtac
    26401 tgcaacagtt tgacgatcaa agccgcaacc agcgtacccg tcaggataaa atccgtctga
    26461 ttgtccaggc gattatcggc gtctggctgg tgactgcgct ggcactgcat ctggcggaag
    26521 ttggtttgat tggtttgtca gtcattattc tggcgacatc attgaccggt gttaccgatg
    26581 aacatgctat cggtaaagcc ttcaccgaat ctctgccatt caccgcactg ttgacggtgt
    26641 ttttctcagt agtcgcggtg attatcgacc aacaactgtt ttcgccgatt attcagtttg
    26701 tgttgcaggc atctgaacat gctcagctgt cgttgttcta tattttcaac ggtctgctgt
    26761 catccatttc ggataacgtc ttcgtgggga cgatttatat caacgaagcg aaagcggcaa
    26821 tggaaagtgg cgctatcacg ttgaagcaat atgagctgct ggcggtcgcc attaataccg
    26881 gtaccaatct gccctccgtc gctacgccga acggtcaggc tgcgttcctg ttcctgctga
    26941 cctctgcact cgcgccattg attcgtctct cttatggccg catggtgtgg atggccctgc
    27001 cttacaccct cgtactgacg gttgccgggt tactctgcgt cgagtttacg cttgctcctg
    27061 taaccgaatg gtttatgcaa atgggctgga tagcaacgct ttgataacaa cttaccgggc
    27121 atataaatgc ccggtttgcc ttttcgcccg ataattgtcc aattgcgtcc tatttttgct
    27181 gcctcctggt ggcgcagcga atgaattggt ttaaactgcg cactctatgc atattgcagg
    27241 gaaatgatta tgttgcgatt tttgaaccaa tgttcacaag gccggggcgc atggctgttg
    27301 atggcgttta ctgctctggc actggaactg acggcgctgt ggttccagca tgtgatgtta
    27361 ctgaaacctt gcgtgctctg tatttatgaa cgctgcgcgt tattcggcgt tctgggtgct
    27421 gcgctgattg gcgcgatcgc cccgaaaact ccgctgcgtt atgtagcgat ggttatctgg
    27481 ttgtatagtg cgttccgcgg tgtgcagtta acttacgagc acaccatgct tcagctctat
    27541 ccttcgccgt ttgcgacctg tgattttatg gctcgtttcc cggaatggct gccgctggat
    27601 aaatgggtgc cgcaagtgtt tgtcgcctct ggcgattgcg ccgagcgtca gtgggaattt
    27661 ttaggtctgg aaatgccgca gtggctgctc ggtattttta tcgcttacct gattgtcgcg
    27721 gtgctggtgg tgatttccca gccgtttaaa gcgaaaaaac gtgacctgtt cggtcgctaa
    27781 tccattcggc gctcctgcgg gagcgctttt tcctgccgct atgtttattt gacccgcagt
    27841 aaatcagaac ttcgcgttgt ataacatggt gaaagcatgg cacgcttcat ctgccattgt
    27901 tgctggatcc cctgcccggc aaaatagagt gttcctctgc cctctttagc attcagcgta
    27961 tccattaccg ccatcaattg ctcactcccg gggcgtggtg cgttgtcatc gaataaattg
    28021 agctgcgcga ctccctgact gaagaaatcc cccagcatca cgcccgcttt ttggtagcga
    28081 tggcccgctt gccagatggc atccagagat cgcgtagcgg cgttaatgat atccctgctg
    28141 tcctgagtgg gcgtcagcag ttttaccgat gcgctattgc cgtaataagg ttcattgaac
    28201 gcaaatggtg acgtcttaat aaacgtggag ataaaccgac aatattgatg ctcgctgcga
    28261 agtttttccg ccgcccgggc agcgtaacta caaatggcct gccgcatcga cggataatcc
    28321 gtgatgcgtt caccaaacga gcgggaacag ataatttcct gcttcgtcgg tgcaaactct
    28381 tccagttgca aacagggttc accgcgcagt tcacgcaccg ttctttcgag cacgacatta
    28441 aaatgtttac ggataaaccg gatatctgaa tctgccaaat ctagaacggt tttgatcccc
    28501 atcgcgtcca gttttttgct gatccgccgt ccaatccccc agacttcatc cacggggaga
    28561 gcagacatta atttacgctg gcgttccaga tttgataaat ccaccacccc acccgtctgc
    28621 cgctgccatt tttttgccgc atgattggca agcttagcca gcgttttggt ctgggcgatc
    28681 cccacaccaa cagtaagatg ggtacgttgt agcaccgttg cgcgaatttc tctgccaaaa
    28741 tcagtcagat cgcgacaatt atgcacacct gtcagatcgc agaatgcctc atcaatactg
    28801 taaatctcga cgcggggcga tagttcttcc agcgtcgaca tcacccgatt actcatgtct
    28861 gcgtaaagct cataattgct gctaaagcaa accacgccac agcgacgaaa cagatctttt
    28921 tgtttgaacc agggatcgcc cattttaacg cccagcgcct ttgcctcagc gtttcgggcg
    28981 ataacgcaac cgtcattatt cgatagcaca accaccggtt taccccataa atcagggcga
    29041 aacaccgtct cacagctggc ataaaacgcg tttacatcac agagggcaaa catcagcgca
    29101 tcgccttaac gacgtggatc accacaccaa agacatccag cgtatcttcg ctactgatgg
    29161 taatgggcga gtacgcactg ttcataggaa taagctgtac cgtcgggcgt agttgcaatt
    29221 ttttcaccgt aaactcgccg tcaacagcag cgatgataat atcaccatgg ctggcggtaa
    29281 tagcgctatc gacaatcagt aaatcaccgt cactaatccc accatcaatc atagaatcac
    29341 cacttgcttt gacgaaataa gtcgcgctgg gatgctggat caacagttga ttcagatcga
    29401 tgcgctgttc aacgtaatct gcggccggtg aaggaaagcc acactgaaca agatcgctaa
    29461 atagcggaaa agtcacaatt tcgcggagat ccgcaggctt gataaacaac ataataatct
    29521 gcctgaagtt atactgtttt tatatacagt agtctgttct tgtcagcaga tcaatactga
    29581 ttcaggctat caatatttgt cgctgcatag actgctgatt tttcgttctc ttatcctgtg
    29641 ctcacgcggc cttctggcga cagcgtccat ccagcagaaa ggaaaaatat cacctggttt
    29701 aaaatagaat cgaagcattc gcccagaaag gcattctcat taaggtactg gatgacggca
    29761 tcaagaaact gtgttctatt gctgcgggcg tagttgaagg gaaactgatt ccagaattga
    29821 agaacaagtt aaaatctgtg cagagtttct ttaccaccct gtctaacacg gttaaacaag
    29881 cgaataaaga tatcgatgcc gccaaattga aattaaccac cgaaatagcc gccatcgggg
    29941 agataaaaac ggaaactgaa acagccagat tctacgttga ttatgatgat ttaatgcttt
    30001 ctttactaaa agaagcggcc caaaaaatga ttaacacctg taatgagtat cagaaaagac
    30061 acggtaagaa gacactcttt gagatacctg aagtctgata agcgattatt ctctctatgt
    30121 actcaaggta taaaatttat cacatttaaa aatacagacg ttttttaaag attgagagtt
    30181 acctgttgat aataaagtat cgggtaactc tcattatgac agagcgcttt caaaaacagg
    30241 gctacgaaat ggcgagcatc cagacgtata ttaagaaagc ccccatcaac atctattaaa
    30301 tttatcactg cgcccagtca ggtttattta agatatgatc ctgccagtca atcacttctg
    30361 attctttcac tgcgatatga cgcacagaga tacgttcacc atgcattgcc gctttcgaac
    30421 cagtaagtag cggatgccac gcaggtaaac ctttaccttc cgccagcaaa cgataagcgc
    30481 aggtcattgg cagccattcg aatgttggca gattttcacg ggttaattta atgcagtcgg
    30541 gttcaaactc gaaacgacgt tcgtagttcc gacattgaca ggttttaata ttgagctggc
    30601 gacaggcgac gttagtgaag tagatttcgt cggtgtcttc atccatcagt ttatgcaggc
    30661 aacactgacc gcaaccatca cacaacgact cccattctgc atcgctcatt tcgtccaggg
    30721 ttttactttg ccagaaaggt acatcgctca tcaggtgttc cgccattacg ttaaaacgca
    30781 ccttataacc agtctggcac agcgatgcaa gttttgccgc cgctttcagg cggcaaaaag
    30841 tattacaaaa cgcgagttgt caaagaatgc ccatcgaaag tgactgtcag ctcatcaccg
    30901 ctttgcaacg ggccgacacc atcaggcgtg cctgtcagca caacgtcacc gaccttgagg
    30961 gtaaaaaact tgctcatata agcgatcagc ggaacgattt tatggatcat gtccgcagtc
    31021 gtaccttgct ggcgttgctc gccgtttacg ctcaggccca gcgttgtatt ttgcgggtcg
    31081 ccggtaaatt ccgccgcggg aataaacccg gaaagcggac aagagttatc aaacgctttg
    31141 gccttttccc acggctgccc ggctttcttc atttttccct gaacatcacg caatgtcaga
    31201 tcgagcgcca cgccgtaacc ggcaatggct ttgcggacat gctcttccgt agcctgacgc
    31261 agcgtcgcgc caatcaacac cgccagttcg acttcatgat gaactgaacc gaaatcggat
    31321 gggatcgcca atggctgccg cagatcgcac agtgccgttt ctggtttaat aaacagcact
    31381 ggctcttcgg gtactgcgct gcccatctct ttaatatgtt tggcatagtt actgccaaca
    31441 cagactactt tactcaccgg ataatccagc agcgcacctt gccagttgtg atgttgatac
    31501 ataacgttcc cctcacctta tcgtggatat gaaaacccgc gccgacaaag ataatgccac
    31561 cgccggatat cggttatttg ttagtgtcgt ctgttttctg ccccatgacg gaaagatgtt
    31621 gcttcagcaa atcttcgggt ggtggcggta actgcaaata gtaaccttgc tcggttaatg
    31681 cctgtttaac cttttcaata tcggcattga ccagtttctt ccgcccatcc agcggaagaa
    31741 tcatcgctaa ctgaggctga ccaaaacctt tcatcagttc ctcaggaaca cgcgaaaaat
    31801 cgtctttttt ttcgacatat aaataggtct ggtcacgttt gctgcttcga taaatcacac
    31861 aaaacatact tttactcttt aagatgccag gttttggcat aagctaacat caatgaaacc
    31921 cgcgccacaa gccagccagc tgtagatttc tacggtttgt tcagtccatg ccccctttat
    31981 aagtaatccc ccggcaaaaa tgccgcgcca ggatttaacc gaacacagga aagccactgg
    32041 aattctcccg tgaaggattg ttatattata acagttcatc gtactcattc tgaacaggag
    32101 actaccaatg aaaattaagg gcatcagtaa ggctgtattg ttgcttgcac tgctaacttc
    32161 cacgagcttt gctgcgggta agaatgtcaa tgttgagttc agaaaaggcc atagtagcgc
    32221 tcagtactcc ggcgaaataa agggatacga ttacgataca tataccttct atgccaaaaa
    32281 aggtcagaaa gtgcatgtga gtatctctaa tgaaggcgct gatacttacc tcttcgggcc
    32341 aggaatcgat gattctgttg atttatccag atattcccca gaactcgata gtcacggaca
    32401 atactcactc cctgcttctg gcaaatatga gctgcgagtg ctgcaaaccc gaaacgacgc
    32461 ccgtaaaaac aaaactaaaa aatataacgt cgatattcaa attaagtaaa tgtcaaccga
    32521 cggggactct ccccgtcata aacgttaacg ccacactcct ctctgtcgct taagaggtta
    32581 atgacgaata gaacataatg taaacaagac atcactcacg acacataaat aacatctttg
    32641 tggtggtttg attgattttt ccactccgct taccatccac accaaaataa cgatcatcac
    32701 gacataattt ttctttaaca tcgcaaaata caccgttaga gaatgtaaat tcgctgggat
    32761 cgtagccttg taatgattgt aagttttcag cggctttttc gccgagatat ttccttgtta
    32821 actctgggga aatgccatct gaactcacac aaatatacgg gtcgcaaaca acgccacacg
    32881 caggagattg aagcccgcca gcgtcatttc cagacgccat tgatgagaac atcatcccca
    32941 cacctgacaa tccgatataa aaaatacgca tcatattcat agcacatcct gataatccaa
    33001 ccgtacaaca cttatgctca tttcatcatc aatccgtaat caaaaccgct gacctggacg
    33061 agttacgatg acctgacaga agtatcagac gtcttctgcg gtttctatga tagagcaatt
    33121 ctgcggcgga tattaagata acgggtatct gttctttaat gatgctgcaa aaaatggaaa
    33181 gttaagaaag cctggcgtgg tgaaaaaata cactcgcctc aatactggat atttaaacag
    33241 gtctgaagat gctgtcacga ttagggtgcg gaaaaaggaa gcgtaaataa gaacaatcaa
    33301 aagtacgacg gcaatgggtt gattgacaag ggtatttttt aagctatgaa tcaacgccat
    33361 ttatcacaga atagactttt actctgaata aatgggaggg tgacttgcct caatataatc
    33421 cagactataa catgccttat agtcttcgga acatcatcgc gcgctggcga tgattaatag
    33481 ctaattgagt aaggccagga tgtcaaacac gccaatcgag cttaaaggca gtagcttcac
    33541 tttatctgtg gttcatctgc atgaggcaga acctaaggtt atccatcagg cgctggaaga
    33601 caaaatcgct caggcccccg catttttaaa acatgccccc gttgtactca acgtcagtgc
    33661 actggaagac ccggtaaact ggtcggcgat gcataaggcg gtttcggcaa ctggtttgcg
    33721 ggttattggc gtaagtggct gcaaagatgc gcaacttaaa gccgaaattg aaaagatggg
    33781 gctgcctatc ctgacggaag gaaaggaaaa atcgccgcgt ccagcccccg caccgcaggc
    33841 tccagcgcaa aatacaacgc cggtcacaaa aacgcgttta attgataccc cagtgcgttc
    33901 cggtcagcgt atttatgctc cacaatgtga tctgattgtt acaagccacg ttagcgcagg
    33961 ggccgaattg attgccgatg gtaacattca tgtctatggc atgatgcgcg gtcgtgcgct
    34021 ggcaggggca agtggtgacc gggaaacgca aatattttgt acgaacctga tggcggaact
    34081 ggtgtccatc gcaggtgaat actggctgag tgatcaaatc ccagcagaat tttatggcaa
    34141 agcggcacga ctgcagttag tcgaaaacgc tttgaccgtt caaccgttaa attgatccct
    34201 ttttaacaag gaatttctat ggcacgcatt attgttgtta cttcgggcaa agggggtgtt
    34261 ggtaagacaa cctccagcgc ggccatcgcc actggtttgg cccagaaggg aaagaaaact
    34321 gtcgtgatag attttgatat cggcctgcgt aatctcgacc tgattatggg ttgtgaacgc
    34381 cgggtcgttt acgatttcgt caacgtcatt cagggcgatg caacgctaaa ccaggcgtta
    34441 attaaagata aacgtactga aaatctctat attcttccgg catcgcaaac tcgcgataaa
    34501 gatgccctca cccgtgaagg ggtcgccaaa gttcttgatg atctgaaagc gatggatttt
    34561 gaatttatcg tttgtgactc cccggcaggg attgaaaccg gtgcgttaat ggcactctat
    34621 tttgcagacg aagccattat taccaccaac ccggaagtct cctcagtacg cgactctgac
    34681 cgtattttag gcattctggc gtcgaaatca cgccgcgcag aaaatggcga agagccgatt
    34741 aaagagcacc tgctgttaac gcgctataac ccaggccgcg taagcagagg tgacatgctg
    34801 agcatggaag atgtgctgga gatcctgcgc atcaaactcg tcggcgtgat cccagaggat
    34861 caatcagtat tgcgcgcctc taaccagggt gaaccggtca ttctcgacat taacgccgat
    34921 gcgggtaaag cctacgcaga taccgtagaa cgtctgttgg gagaagaacg tcctttccgc
    34981 ttcattgaag aagagaagaa aggcttcctc aaacgcttgt tcggaggata agttatggca
    35041 ttactcgatt tctttctctc gcggaagaaa aacacagcca acattgcaaa agaacggttg
    35101 cagattattg ttgctgaacg ccgtcgcagc gatgcagaac cgcattatct gccgcagttg
    35161 cgtaaagata ttcttgaggt catttgtaaa tacgtacaaa ttgatcctga gatggtaacc
    35221 gtacagcttg agcaaaaaga tggcgatatt tctattcttg agctgaacgt gaccttaccg
    35281 gaagcagaag agctgaaata agccccctgt aaaagcgcat ttatcttcaa ggcagagtca
    35341 tctctgcctt gagtttttca tccctctcat ccacgttgtg gtaaagcggc gagtattctt
    35401 gctgatacta ctcattgcta tttccccccc ctttacacct taaggctgtt cccacgcaca
    35461 gaacaaaatg tttacgcctg gttgagtaaa taaccttatt gttagcatgg gtatccaggg
    35521 agatgataac ccgcaatttc attattcatt gttctccaat aggatgaggt ttcccgccgt
    35581 aactggcggg ctttttttgc cccagaattt tcccttttag caccctgtaa acgaaaacag
    35641 cgccgaaacg cagttaatcg ttgatggtca gaacggccag ttcacaccgg ccaccgcatt
    35701 ccacggggac tccacaccgg caccacggtt atacccaccc cgagatgccc gcttaacata
    35761 ctgctgaatg aggctttaat acctgcctgg tatattccac gtctgcccga caaatcattg
    35821 acaaaattac cgtcactatt caccttcacc cggttatcat cgacaaattc tttgcgcaca
    35881 gccgccttca gccagggttc aatttccata ccgttcccca gacgcatgtt gtagctcagc
    35941 gttgcgccca gttcacgata tatactgcgg gtatcgactg atttcgattc catgcattgg
    36001 ataaatgata gtagcgtcta agtgacctta gctctgctgc aacatcagcc cgcaggcacc
    36061 agaccagggg attcatcctg aagagacagc gcaaatgtat tgtgttcacc gctcatcaaa
    36121 gacatcatga tgaaatgatg atatcccgta taagaaagag gcatttttta aacgcagtgc
    36181 gctgaagtgt tgttggataa aaaacactct tttctgataa tactgtcgta cgcttatttt
    36241 tcgacaatga ggccgtccac aaaataaaat gactaatgta atcgttgcta atgaatatct
    36301 tctgctcaca taacaatcac acaataatat tgataaatca gattatctta cctttacaac
    36361 attgtattaa cagccaatga cacttcttga ataaaaatat tgtcaatcaa tgagttattt
    36421 ctcatttgag attattctca ttcccgtaaa aaacataatt cctatcatca cagtcacgct
    36481 cattttgaat tatctgaata atagcgagcg ttctttagtt aagcagatct taattgaaga
    36541 cgaaattatt gtgtgtgcaa cttacttaat accggacaac taagttgaag aaaaaaatac
    36601 tcgccttcgg gcttatctca gcattgttct gctccacgcc agcaatggcg gatatgaatc
    36661 gcaccacgaa aggtgcattg ctaggtgcag gcgttggttt acttactggc aatggtgtta
    36721 atggcgtact gaaaggtgca gctgttggcg ctggtgttgg tgcagtaaca gaaaaaggcc
    36781 gtgacggtaa aaatgcgcgt aaaggtgcaa aagtgggtgc cgccgttggt gctgtcactg
    36841 gcgttctgac cggcaatggc ctcgaagggg cgattaaagg tgccgtgatt ggcggtacgg
    36901 gtggtgcaat tctgggtaaa atgaaataag gaatgatgat gaaaaaattt gctttactgg
    36961 cgggtctgtt tgttttcgca ccaatgacct gggcgcagga ctacaatatt aagaacggtt
    37021 tgccatcaga aacctatatt acttgcgcag aagccaacga aatggcaaaa actgacagcg
    37081 cacaggttgc agaaattgtt gcggtaatgg gtaatgccag cgttgccagc cgtgatttaa
    37141 aaattgagca atctccggaa ctgagcgcca aagtggtaga aaaactgaat caggtttgcg
    37201 ctaaagatcc gcaaatgctg ttgatcacgg caattgatga caccatgcgt gctatcggca
    37261 aaaaataata tttcatatgt taccgcgtcg atgaattcga cgcggttttt tagctaacgg
    37321 gcgggatcag aacttatatt tcaggcccac catcattgcg gtgtcattgt agccattatc
    37381 acccagctgc acgcccacat taccccagac gctggccgcc ggattcagat tgccatttac
    37441 gccatgtttc atttccccca gattacgagc cccgtcttgt tcgactttca caccgttcat
    37501 tgagacagca aaatctttac tgttatggat cccgttcatt tcaacaaaag gttcaaagtc
    37561 gtcaccgtgc ggaccgctgt ttttctcctg agtacgaata aaggtgcgga aaccaagtcg
    37621 gctctggatg ttgtaatttg cgtcattctc aatacgtgag ccattggctt ccgtgtgcgc
    37681 attatgatcg acgcccatcc agatggcctg tgccgaggtc gttctcaact gtccgttgct
    37741 gtcacgccag gcattatgcc cgccaatttg acatagccaa agttggcttg aacgctcctg
    37801 ttcagttaca ggatcgatat agcgcgtttc acccgcacga tcgttcagac gcgtaacaaa
    37861 aagagtgtta gcggctgcca ggttggcgac gtaactgcca gcgtcgggtc gcaggacggg
    37921 ggtaggcgtt tctgttgatt ctgaagtgac attggaaaaa aatcactctc taccattgta
    37981 tatttttgca atgggggctt tagtgccatt tgttgtaata gaactttttt atatcaatgt
    38041 taccttgtcg aatagcaact gcataacttc catcagccac agtttcaagt accacataat
    38101 ctaaattaat atatgcttta ttcccattag cataagtacc atagctatta ataccattag
    38161 ttgttatgga accaccattc atttttaaat cagcacggct aataacttcg taactgttag
    38221 aatcacaaac ttcatcatct acagcatcga cacatgttcg agactctcca ggacttgaac
    38281 atgcaagaac tcctactgca ttttccccat aggtaacaat gttcgtttta tctgtggttt
    38341 caagactggt gttattttcc acagtcccag aatcattaac ctgacttaaa aatcccgctg
    38401 aatatgcccc ctcgtctcga ctgaattatc accattcata acgatggtgc caccaaattc
    38461 actgactact gcgctggctg ttatccctcc attttctttg tcagatacgc ttccagaggt
    38521 cttaatattg ctatcgctta tatataatac tttgttttgg ctatcaacag aaataccata
    38581 agatccatca ccactagtca tcacactggc attatttata tatccagtta caccgtcatc
    38641 cactttcaca gcatggcttt cgtcttaagt gattagatac tctccattac ttgtagaagt
    38701 attatttttg atttcaatcg gtgattcttc atcggttata taggaaatta cactataatt
    38761 atccaacaat tgtgttaccc accgccagag caataagtcc taaactgaac ccggggagt
//
LOCUS       DAFGPF010000036        38638 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFGPF010000036 DAFGPF010000000
VERSION     DAFGPF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38638
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.036"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            225..1880
                     /gene="aslA"
                     /locus_tag="LSX49_002075"
     CDS             225..1880
                     /gene="aslA"
                     /locus_tag="LSX49_002075"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase AslA"
                     /protein_id="HBL7168489.1"
                     /translation="MEFSFSPKLLVVAVAAALPLIASAADTPSTATARKGFAGYDHPN
                     QYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVG
                     FNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMY
                     GQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYT
                     EWRDVHVNPEVALSPDRSEYIQKLPFSKDDVHAVRGGEQEAIADITPKYMEDLDQRWM
                     EYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDIFA
                     NLYKALEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWK
                     GMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQS
                     NRKAEHYFLNGKLSAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLY
                     TDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD"
     gene            complement(1971..3206)
                     /locus_tag="LSX49_002076"
     CDS             complement(1971..3206)
                     /locus_tag="LSX49_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HBL7168490.1"
                     /translation="MQQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYHEKPVTH
                     MDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISN
                     SFQTNGVLLDDEWCGFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
                     QKHHVDYNVLVCVNRTSALQPLQVYDFLCDAGVEFIQFIPVVERLANETAAHAGLKLH
                     APGDIQGELTEWSVCPQEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMLQQMIAEMIDSPQQQAFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPELNYLCAGYQRYFRHLPPYLKAMVDLL
                     AHGRPASDIMQAHLLVVNK"
     gene            complement(3353..3429)
                     /locus_tag="LSX49_002077"
     tRNA            complement(3353..3429)
                     /locus_tag="LSX49_002077"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3393..3395),aa:Pro,seq:tgg)
     gene            complement(3472..3558)
                     /locus_tag="LSX49_002078"
     tRNA            complement(3472..3558)
                     /locus_tag="LSX49_002078"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3522..3524),aa:Leu,seq:cag)
     gene            complement(3579..3654)
                     /locus_tag="LSX49_002079"
     tRNA            complement(3579..3654)
                     /locus_tag="LSX49_002079"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3619..3621),aa:His,seq:gtg)
     gene            complement(3713..3789)
                     /locus_tag="LSX49_002080"
     tRNA            complement(3713..3789)
                     /locus_tag="LSX49_002080"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3753..3755),aa:Arg,seq:ccg)
     gene            complement(3892..5277)
                     /locus_tag="LSX49_002081"
     CDS             complement(3892..5277)
                     /locus_tag="LSX49_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL7168491.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLTVTAIYKVFGL
                     NRHGKAHKLEE"
     gene            complement(5468..6208)
                     /gene="rffM"
                     /locus_tag="LSX49_002082"
     CDS             complement(5468..6208)
                     /gene="rffM"
                     /locus_tag="LSX49_002082"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HBL7168492.1"
                     /translation="MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(6211..7563)
                     /gene="wzyE"
                     /locus_tag="LSX49_002083"
     CDS             complement(6211..7563)
                     /gene="wzyE"
                     /locus_tag="LSX49_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HBL7168493.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGAAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
                     "
     gene            complement(7560..8639)
                     /gene="rffT"
                     /locus_tag="LSX49_002084"
                     /gene_synonym="wecF"
     CDS             complement(7560..8639)
                     /gene="rffT"
                     /locus_tag="LSX49_002084"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HBL7168494.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPS
                     QFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
                     LYFPTRMDPSLNMMANDRQREGKMTILVGNSGDRSNEHIAALRAVYQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQTLSEKLEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLVSVDKN
                     TIAFFSPNYLQGWQRALAIAAGEVA"
     gene            complement(8636..9886)
                     /gene="wzxE"
                     /locus_tag="LSX49_002085"
     CDS             complement(8636..9886)
                     /gene="wzxE"
                     /locus_tag="LSX49_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HBL7168495.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSTLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEVSQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(9888..11018)
                     /gene="rffA"
                     /locus_tag="LSX49_002086"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(9888..11018)
                     /gene="rffA"
                     /locus_tag="LSX49_002086"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HBL7168496.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNINETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKNGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGEHFG
                     EFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(11023..11697)
                     /gene="rffC"
                     /locus_tag="LSX49_002087"
                     /gene_synonym="wecD"
     CDS             complement(11023..11697)
                     /gene="rffC"
                     /locus_tag="LSX49_002087"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HBL7168497.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRISPDAALLTPDALAPWSRV
                     QAKIAASNTGELDALQQLGFSLIEGEVDLALPVNNVSDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASGRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
                     TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(11675..12556)
                     /gene="rfbA"
                     /locus_tag="LSX49_002088"
     CDS             complement(11675..12556)
                     /gene="rfbA"
                     /locus_tag="LSX49_002088"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL7168498.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(12575..13642)
                     /gene="rffG"
                     /locus_tag="LSX49_002089"
     CDS             complement(12575..13642)
                     /gene="rffG"
                     /locus_tag="LSX49_002089"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL7168499.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVVVVDTLTYAGNLMSL
                     APVAQSERFAFEKVDICDRAELARVFTEYQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWTALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKPLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVAHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     ESWWKQVQDGSYQGERLGLKG"
     gene            complement(13642..14904)
                     /gene="wecC"
                     /locus_tag="LSX49_002090"
     CDS             complement(13642..14904)
                     /gene="wecC"
                     /locus_tag="LSX49_002090"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HBL7168500.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGELADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRANELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(14901..16031)
                     /gene="wecB"
                     /locus_tag="LSX49_002091"
     CDS             complement(14901..16031)
                     /gene="wecB"
                     /locus_tag="LSX49_002091"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBL7168501.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(16087..17133)
                     /gene="wzzE"
                     /locus_tag="LSX49_002092"
     CDS             complement(16087..17133)
                     /gene="wzzE"
                     /locus_tag="LSX49_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HBL7168502.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIVFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(17145..18248)
                     /gene="wecA"
                     /locus_tag="LSX49_002093"
     CDS             complement(17145..18248)
                     /gene="wecA"
                     /locus_tag="LSX49_002093"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HBL7168503.1"
                     /translation="MNLLTVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGKLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(18488..19747)
                     /gene="rho"
                     /locus_tag="LSX49_002094"
     CDS             complement(18488..19747)
                     /gene="rho"
                     /locus_tag="LSX49_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBL7168504.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(19832..19933)
                     /gene="rhoL"
                     /locus_tag="LSX49_002095"
     CDS             complement(19832..19933)
                     /gene="rhoL"
                     /locus_tag="LSX49_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide RhoL"
                     /protein_id="HBL7168505.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(20074..20403)
                     /gene="trxA"
                     /locus_tag="LSX49_002096"
     CDS             complement(20074..20403)
                     /gene="trxA"
                     /locus_tag="LSX49_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HBL7168506.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            20534..21799
                     /gene="rhlB"
                     /locus_tag="LSX49_002097"
     CDS             20534..21799
                     /gene="rhlB"
                     /locus_tag="LSX49_002097"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HBL7168507.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            21935..23419
                     /gene="gppA"
                     /locus_tag="LSX49_002098"
     CDS             21935..23419
                     /gene="gppA"
                     /locus_tag="LSX49_002098"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HBL7168508.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPPQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLTVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFEQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFANRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIDQESQWQSYVHWPLEVH"
     gene            complement(23466..25487)
                     /gene="rep"
                     /locus_tag="LSX49_002099"
     CDS             complement(23466..25487)
                     /gene="rep"
                     /locus_tag="LSX49_002099"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HBL7168509.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAEAKGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGTELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            25574..25855
                     /gene="ppiC"
                     /locus_tag="LSX49_002100"
     CDS             25574..25855
                     /gene="ppiC"
                     /locus_tag="LSX49_002100"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HBL7168510.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     gene            complement(25901..27376)
                     /gene="ilvC"
                     /locus_tag="LSX49_002101"
     CDS             complement(25901..27376)
                     /gene="ilvC"
                     /locus_tag="LSX49_002101"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBL7168511.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     VNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            27526..28416
                     /gene="ilvY"
                     /locus_tag="LSX49_002102"
     CDS             27526..28416
                     /gene="ilvY"
                     /locus_tag="LSX49_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HBL7168512.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEDDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSADKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCV
                     QKKRLHEPLIEAFWKILPNH"
     gene            complement(28413..29957)
                     /gene="ilvA"
                     /locus_tag="LSX49_002103"
     CDS             complement(28413..29957)
                     /gene="ilvA"
                     /locus_tag="LSX49_002103"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HBL7168513.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIAQHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTHWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(29960..31810)
                     /gene="ilvD"
                     /locus_tag="LSX49_002104"
     CDS             complement(29960..31810)
                     /gene="ilvD"
                     /locus_tag="LSX49_002104"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBL7168514.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQDDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDIIVTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDTLDDDRSNGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQEARGNKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(31875..32804)
                     /gene="ilvE"
                     /locus_tag="LSX49_002105"
     CDS             complement(31875..32804)
                     /gene="ilvE"
                     /locus_tag="LSX49_002105"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HBL7168515.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(32824..33087)
                     /gene="ilvM"
                     /locus_tag="LSX49_002106"
     CDS             complement(32824..33087)
                     /gene="ilvM"
                     /locus_tag="LSX49_002106"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HBL7168516.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(33084..34730)
                     /locus_tag="LSX49_002107"
     CDS             complement(33084..34730)
                     /locus_tag="LSX49_002107"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HBL7168517.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDILGLSLACTKHSFLVQSLEELPRIMAEAFDVASSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVSALRE
                     FLAATKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDPAEMNKLRQAHVALQGDLNALLPALQQPLNIDDWQQHC
                     AQLRDEHAWRYDHPGDAIYAPLLLKQLSDRKPADCIVTTDVGQHQMWAAQHIVHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITHKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(34733..34783)
                     /locus_tag="LSX49_002108"
     CDS             complement(34733..34783)
                     /locus_tag="LSX49_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168518.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(34870..34968)
                     /gene="ilvL"
                     /locus_tag="LSX49_002109"
     CDS             complement(34870..34968)
                     /gene="ilvL"
                     /locus_tag="LSX49_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HBL7168519.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            35321..36841
                     /locus_tag="LSX49_002110"
     CDS             35321..36841
                     /locus_tag="LSX49_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312727.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBL7168520.1"
                     /translation="MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKE
                     ARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGRYDLPIAIALLAASEQLTANKLD
                     EYELVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLIADHL
                     QAVCAFLEGKHALEHPKPTNAVSRALQHDLSDVVGQEQGKRGLEITAAGGHNLLLIGP
                     PGTGKTMLASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLT
                     AMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITY
                     PARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGI
                     LSKTVVPGENSTTVKQRVMAARERQFKRQNKLNAWLDNPEIRQFCKLESEDAQWLEET
                     LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAVSYRAIDRLLIHLQKLLT"
     gene            complement(36866..37204)
                     /gene="maoP"
                     /locus_tag="LSX49_002111"
     CDS             complement(36866..37204)
                     /gene="maoP"
                     /locus_tag="LSX49_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HBL7168521.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            37323..38162
                     /gene="hdfR"
                     /locus_tag="LSX49_002112"
     CDS             37323..38162
                     /gene="hdfR"
                     /locus_tag="LSX49_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HBL7168522.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLD
                     EVY"
     gene            complement(38258..38333)
                     /locus_tag="LSX49_002113"
     tRNA            complement(38258..38333)
                     /locus_tag="LSX49_002113"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38298..38300),aa:Trp,seq:cca)
     gene            complement(38342..38418)
                     /locus_tag="LSX49_002114"
     tRNA            complement(38342..38418)
                     /locus_tag="LSX49_002114"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38382..38384),aa:Asp,seq:gtc)
     gene            complement(38473..38588)
                     /gene="rrf"
                     /locus_tag="LSX49_002115"
     rRNA            complement(38473..38588)
                     /gene="rrf"
                     /locus_tag="LSX49_002115"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         9442 a        10563 c         9738 g         8895 t
ORIGIN      
        1 cagcatcaat aatcaacgcg atataacatc accgccttac atatcacctg cgccagaggt
       61 aggattgaaa acgctctcct gattttccaa ttcattttct ggataaataa ataatttatt
      121 tttatcacca ttatttatgc aatcatcctg tcagggagag ggatctcaat tatcaatgct
      181 taattacgtc atcattttga cgacatgaaa ccggagcatt ttgcatggaa ttttcgtttt
      241 cacccaaact tcttgttgtt gctgtcgccg cagctcttcc tctcatagcc agcgcagcag
      301 ataccccgtc aaccgccacc gcacgcaaag gctttgccgg atacgatcac ccaaaccagt
      361 atctggttaa accggcgacc actattgccg acaacatgat gccggtgatg cagcatcctg
      421 cacaagacaa agaaacccag cagaaactgg cggaacttga gaaaaaaacc ggtaagaaac
      481 cgaacgtggt tgttttcttg ctggatgatg tgggctggat ggacgttggc tttaacggcg
      541 gcggcgtggc ggtgggtaac cctacaccag atatcgacgc cgttgccagc caggggctga
      601 ttttaacttc ggcgtattct caaccgagtt cttccccaac ccgcgccacg attctcaccg
      661 gacaatactc catccaccac ggcattctga tgccgccaat gtacgggcaa ccgggcggtc
      721 tgcaagggtt aaccacgctg ccacagttgc tgcacgatca gggctacgtc acccaggcta
      781 tcgggaaatg gcatatgggg gaaaacaaag agtcgcagcc gcagaacgtt ggctttgatg
      841 atttccgcgg ctttaactcg gtatctgata tgtataccga atggcgtgat gttcatgtca
      901 acccggaagt cgccctgagc ccggatcgtt ctgaatacat ccaaaaactg ccgtttagca
      961 aagatgacgt tcatgccgtg cgcggcggtg aacaggaagc cattgccgac attacgccga
     1021 aatatatgga agatctggat caacgctgga tggaatatgg cgttaagttc ctcgacaaga
     1081 tggcgaagag tgataagcct ttcttcctct attacggcac tcgcggctgt cacttcgata
     1141 actacccgaa cgccaaatat gcgggtagct ctccggcgcg cacctcttac ggcgactgca
     1201 tggtggagat gaacgatatc ttcgccaatc tgtataaagc actggagaaa aacggtcagc
     1261 ttgataacac gctgattgtg ttcacctctg ataacggtcc ggaagccgaa gttccgccgc
     1321 acggtcgcac gccgttccgc ggtgcgaaag gttctacatg ggaaggcggc gttcgtgtgc
     1381 caaccttcgt ttactggaaa ggcatgatcc aaccgcgtaa atctgacggc attgtcgatc
     1441 tggcggatct cttccctacg gcgctggatc tggcggggca tcctggggcg aaagtagcga
     1501 atttagtacc gaaaaccacc tttatcgatg gtgtggacca gacatctttc ttcctgggaa
     1561 caaatggtca gtctaaccgt aaggccgagc attacttcct caacggtaaa ctttctgctg
     1621 tgcgtatgga tgagttcaag tatcacgtcc tgattcagca accttacgct tatacccaga
     1681 gcggatatca gggtggattc accggcacag taatgcaaac ggcgggatcg tcggtgttta
     1741 acctgtacac cgatccgcag gaaagcgact ctatcggcgt gcgccatatc ccaatgggtg
     1801 taccgctaca gaccgaaatg catgcgtata tggagatcct gaaaaaatat ccaccacgcg
     1861 cgcagattaa atctgattaa gccggcgcta tcgctgagat ctacctttgc cggatgcgat
     1921 gctgacgcat ccgacaatca accgcaggcg gccacaaaat ggctgctttt ttacttattc
     1981 accaccagca aatgcgcctg cataatgtcg ctggccggac gaccgtgcgc cagcaaatca
     2041 accattgctt taagatatgg cggtagatgg cggaaataac gctgataccc ggcacacaaa
     2101 taattcagct cgggtttgcc gctggcatcg agcataaagc ggtgtttcgg gcagcctccc
     2161 cagcacgctt ttaacacgtt gcaactgcga cactgtgccg gtaactgctt gaatttatct
     2221 tcaccaaatg cctgctgttg cggggaatca atcatttctg caatcatctg ctgaagcata
     2281 ttccctagtc gatactgcgg ataaacatag tgatcgcagg cataaacgtc accgttgtgc
     2341 tcaacaatca ccgagcgccc acaggttggc tgatgatggc aaaccgcgcc cggtgcgccg
     2401 acaaaattgg cgaacgccca ttcgatattc attacgaaaa tcttgccgac gtcgcgctta
     2461 atccagtggt cgaaaatcgc caccagaaac tcaccgaact cttgcgggca caccgaccat
     2521 tccgtcagtt cgccctgaat atcgccggga gcatgtagct taagtccagc atgagcagcc
     2581 gtttcattag ccaggcgctc gaccaccgga ataaactgga tgaactcaac acctgcatca
     2641 cacagaaaat catagacttg caaaggttgt aacgcactgg tgcgattgac gcagaccagc
     2701 acgttatagt cgacatgatg tttttgcagg agcgtcaggg cacgcatcac cagcttatgc
     2761 gtgggtctgc cacctttggt cacgcgatat tgattgtgga tctcagccgg accatccagc
     2821 gataacccta caagaaaatg attttctgcc agaaatccac accattcgtc atcgagcagc
     2881 acgccgttag tctggaagct attacttatc ttcctgccag caccatattt cgcctgtagc
     2941 gccacggcac ggcggtaaaa ctccagcccg agtaacgttg gttcgccgcc ctgccaggta
     3001 aaagccactt cgttttgggt ttcgctggca gcgatatagt gacggacata cgcttccagc
     3061 gtgtcatcgt ccatatgcgt gactggcttt tcgtggtaaa gggattgttt ttcgagataa
     3121 aaacagtagt cacagttcag attacaatca gaaccgctcg gtttcgccat cacatgaaaa
     3181 gcacgcgttg gaacctgttg ctgcatggtc gctccttgcc tgaagtcatc cttcaataag
     3241 ttaagggcga aatcataccg tggcgcaatg cgttattacg ggcgtttatt gcgaagggaa
     3301 agtgacgaaa tgcacagaaa acaaaaaacc ccgccgaagc ggggttcaaa attggtcggc
     3361 gagagaggat tcgaacctcc gacccactgg tcccaaacca gttgcgctac caagctgcgc
     3421 tactcgccga aatactgctt tttgaatttt tagttcaatt ctttaaagtc gtggtgcgag
     3481 gggggggact tgaaccccca cgtccgtaag gacactaaca cctgaagcta gcgcgtctac
     3541 caattccgcc accttcgcat tgtcacaact tctaataatg gggtggctaa tgggattcga
     3601 acccacgaca actggaatca caatccaggg ctctaccaac tgagctatag ccaccactac
     3661 aaatcttgtt acgcggtatt actaccaccg cagctcaagc gccgggacta aatggcgcgc
     3721 ccgacaggat tcgaacctga gacctctgcc tccggagggc agcgctctat ccagctgagc
     3781 tacgggcgct tagcgccgtt gcgggggtgg ataatacgga cttcccaccc ctctgtctag
     3841 tcccttttta aataaattgc gcgtttggtt acggtttgtg cgttttgctg cttattcctc
     3901 cagtttatgc gctttaccgt ggcgattaag cccaaaaact ttataaatcg ccgtcaccgt
     3961 cagcataaag atgatgccga caaacagcga catacgcgta tcttcattaa agtacatgcc
     4021 gatcaaaacg caaatcagga atgccattgt tacgtagttg gcccaaggga acaggattga
     4081 gcggaacgga tggctggcaa ttgccgcttt atgcgcacga cgaaaacgca gctggctaat
     4141 caatatcaca aaccatggca ccatccccgg aagcacgctg gcactgtaga catagacaaa
     4201 cacacgctgc ggattgggaa tgatgtagtt caggcatgag ccaattagca gaatagcaat
     4261 agataccgcc acacccgcaa ccggtacgcc gtgacgggaa actttcgcca tcgccgccgg
     4321 taactgacgg tttttcgcca gtgcatagag catacgtccg caactgtaca tgccactgtt
     4381 acagccagaa agcgctgccg tcagcaccac aaagttaata atgcccgccg cagcggtaat
     4441 gccgattttg gcgaaagtca gtacgaacgg gctgccgttg ctgcctattt cattccacgg
     4501 gaagatggta acgataacga aaatcgcgcc tacgtagaaa atcaggattc gccacagcac
     4561 cttgcctaca gcgctacgca gcgtcacctg cggattcttc gcttcaccgg cagtaatgcc
     4621 aatcagctcc acgccctggt aggacgccac cacaatacac aatgcggtca ggaacccttt
     4681 ccagccaccc gcaaagaaac cgccatgctc tgtgagattg ctaaaaccaa tcgactgccc
     4741 gccattgcca aagccaaaga aaatcacgcc caggccaatg acaatcatca cgataatcgt
     4801 ggtgactttg atcatcgcga accagaactc gatttcgccg tacaacctca ccgcagccag
     4861 attcgccaac gccaccagcg ccaccgcgat caatgcgggt atccactgcg ccatctccgg
     4921 gaaccagaac tggacataaa cgccaatggc ggtgatttct gagatcccca ccgccatcca
     4981 cataaaccag taagaccagg cggtgagata gccaaagaac gggctcatat aacgatgcgc
     5041 gtaaacggcg aacgaaccgg taaccggttc gaggaacaac atttcgccca ttgaacgcat
     5101 gatgaaaaag acgaacagcc cggcgatgat ataggccaac aatacggatg gcccggccca
     5161 tttcagggta ctggcggccc ccataaacag gccgacgcca atggtgcccc ccagggcgat
     5221 gagttcgata tgtcgagctt ccagcccacg ctgtagctct ggtttgttat ctgccataaa
     5281 tcctcgtgtt gtgtttgcat gctttccggt gttaccggtt atcgttatgg gtacatcgag
     5341 tgttgcgaat gttttcgtaa ttcaggagaa atggcaaata aagcattaaa aatttgaatg
     5401 ctttgtgtaa taaaaaagca gacaggcgac ggagtgacca cttcgtcgct ttacaaagag
     5461 aggaaaatca gaggttgccg gtatagtgcc agcgtaaata acgcagcaaa cgaagctgac
     5521 gcttaatgcg gctcggctgc gaaagcaggc ggtagagcca ctccagcccc agcgtttgcc
     5581 agattttcgg tgcgcgtttt acgtgaccgg tgaaaacatc gtaggtcccg ccaacgccca
     5641 tatacagcgc atctggatgc accagacggc agtcgcgcat gaagatctcc tgctttggcg
     5701 atcccatcgc aacggtgacg atttgcgctc cgctggcatg aatgcgttca aacagcgcct
     5761 gacgctgctc gggtttaaaa taaccatcct ggctgccaac gatattcaca ttccactggt
     5821 tgcgcagttt agcttcagtt tgcgccagca cttcaggttt accgcccaca agaaataccg
     5881 gtgtcccttc tttgcctgcg cgcgccatca gctcttccca gagatcggcc ccagcaacgc
     5941 gggaaacctg cgcctgcggg tactttttac gtactgaacg tacaacgctt atgccatccg
     6001 catatttaaa ttcggcagcg ttaattagct cccggacctc ggcgttatct tcaatggtca
     6061 gcattttttc ggcattaatg gcaaccagcg ttccttgctt aagctgcccg tcagcgaaca
     6121 gataatcgag ggcgtgctgc atatcacgcc aaccaatcaa ctgtaagcca cgcagcgtat
     6181 aggtcggtgc cgtggtgttg ttattcatta ttatccttca acctgcgtcc ggagcgatga
     6241 ttttgttcgt ttatgaatga gtccggcgct ttcaaaaagc cagtacaaca gttttgcgat
     6301 catcagacat gcgccgaaga ccacgataaa aaagaccacg cgtgagacaa acgaatccag
     6361 cccttcacgc gccagcacga tcatattgaa gatcgccccg aagcagaaac tgtgcaatat
     6421 cgcagcctta tagcgattag tctcgcggtt gcccagctca tacagccagt cgaaccattt
     6481 gatgatcagt ccaacaacaa tcgccccgag cgggatgaac aacgcgccgc ccatcaccac
     6541 cagtgagcct ataagcgtag gcgagatcgc cagtccggag tggttattca gcacttccca
     6601 ggtaaagtag ttggcggagt tcagcaccat actcgggcga cccggccaca gccaggaagg
     6661 gataaagaca tagaaatcgc ggacaattgg agccaggccc tggaagtcga tgttgtcgta
     6721 gttctgcaac agcaacgcca gattctccca cggtgaaaag gtgtcgcgag tgagatagag
     6781 aaacgtatag aacgcttcat cgccgctcac attcattcca tagcgtttta acgccagcca
     6841 gaacatgccc acaatcccca gcacgcccgc cgccgccagc atccacaacg aaatccagcc
     6901 gcgaataatg ccaataaaca ggaagatagc gaatgcgatg atgatattgg cgcgagtgcc
     6961 gccgacaatc atataagtca gcaagccaaa agcgaccgtg ctgacgagga aaaacagcca
     7021 cgctttgctg tcctggcgca gaaagtagac caccagcatc gccgggatga aaaagtaaaa
     7081 gaagcgtttt aacgccacgc cggagacttc actggagaag atctgactgt aggagttaag
     7141 ccggaacagc aaaaagccgt tgtgcatgaa gaagatgccg acgcttacca gcgcgatgcc
     7201 catcaggatc acccacgtga gattggtttc cacgcggttc atggtaaaca gcggacggcg
     7261 cggtacatca gcaacgcgtt tgcgtaggcg ggttttgtag gtgacgtagt aaaccgcgta
     7321 gaagcagccc gcagaaagca acgcctgcaa caagatttct ggcggcgcgg caccaacatc
     7381 aaagcgaaaa accagcacgc tggtcagcgg gaagccgaag aaaaaggtga gcaaaaacag
     7441 caatgaaaag aagacattga agttaaagcg cacacggcga aactcaaacc aggtcagcgt
     7501 ggcaataaac agcgtgcaga gcagccagac aacaaacagg ccactgaatt gcagcagact
     7561 catgcgacct ccccggcggc aatcgccaac gcccgctgcc agccttgcag atagttcggg
     7621 ctaaagaagg caatggtgtt tttatccacc gacaccaact ggcgctgcgc ttcacgcaca
     7681 atatcctcgt tgagatcgtc ggtagtaaac agcaccggca aatgctgttc cgtcatatcc
     7741 tgccagaacg gattttcccg gttaagcaca caaggaatgc ccgcctgaat cagtaagcac
     7801 agcgtaccaa tgccctgctg gcgggcaaaa ataaagtaac caagatcgca ctgacgaagt
     7861 agcgccagat aggcgtcaaa ttccagtttt tcgctcagag tttgtagatt ttcttcgctg
     7921 aataactcca gccccgcctg acgaacttcc tcgatgtacg cttcgttatt aggcggatat
     7981 cccatcggca ccaccacttt taccgtatcg ccaaattgct gataaacggc gcgcaaggca
     8041 gcaatatgtt cattgctgcg gtcaccggag ttccccacca gaatggtcat tttcccttca
     8101 cgttgccgat cattcgccat catattgagt gaagggtcca tccgcgtcgg gaagtacagc
     8161 agttctcccc gcacctttgg atgcgttttg gcaaaaaagc tcaaatcacc gcgggtggca
     8221 aatacacagc cgactctctt ttgcgccagg cgacgtagcg ggtaaaaaag cttatatctc
     8281 aagccactgg aaagctcgta caggtctgcc ccccagatat gccagtaaaa ctggctgggc
     8341 ttaatgccac cactcagcag agccagccac agtgtgggat tgaactgacc gtggaagaaa
     8401 aaacgctgct gacggttagc ttttgctttc gcgatgaccg cttccgccag cgattttttc
     8461 ccagggaaaa attgcacaga aagcgccgga cagctatcac ttaagccgtc gtccttgcca
     8521 acaaccataa actcgcgcgc gtgctcgctc gtcgcggcca gcgcgtcatt gaaaaaccgc
     8581 aaaacggttc ggttatggtg agggatatcc gatcccagta cgtgaatcag tacagtcatg
     8641 cccgcctacg ccagagtaaa aacacgccac aacaaagaga aaaatagacg atataggttg
     8701 ccatataggc ctgcgccgcg cccagtgcac catgcgcagg gattagccag tgggcaaata
     8761 ccatcaataa agtgaactgg ctgacttccg ccagaatata aaaccgcagt gacgctttgg
     8821 cgatcaccag ataaccaaag acataagcgc ccacttttaa cacatcaccc accaactgcc
     8881 aggcaaagag atcgcgcata gcggtaaatt tattcgacaa cagcagccag atagcaaaat
     8941 cacgcagcaa ccagacggta aaactcgccg ccgccactgc cggcaagacg aatttaagcg
     9001 atttaaccac ttcccgggtg atatcgcgct tttccgttag ccgcgacaac gtgggcagca
     9061 aatatacgct gaacgatgcc gtaataaatt gcaggtaggc atcggaaata ctgctcaccc
     9121 cttgccagat ccccacctca tcccagctat actgcgccgc cagcagttta cgcatcatga
     9181 tgtaagcaac aggcaaggtc accgacgtaa tcaacgccat gagcgtaaat ttgctcaact
     9241 gccctgccag accgttatcc cagctgggtt tcagatagct taacgggatg acaccacgtt
     9301 tgatcaacat gatggcggca ggaattacca ccagcgcggg aatcagcgcc agacccagca
     9361 acgccccttc ataaccgccc aaacggtaac tgacgtagta cgcgagaacg ccaatcaagc
     9421 tgccaacaat cagagataac gcattacctg cggcatcgcg aaagcctttc atcagcgcca
     9481 gtaacaggtt gccccaggcg atccccattt gcaccagcgc cactaaacgc accagcccct
     9541 gatagtcggt attaccaaac aatccctggc tgattggcgc agctgccagc acaaaaacca
     9601 gcgccatcag cgtagagaaa ccaagtacca tcgctgatga agtgccgacc acgcggcgca
     9661 gctgttgcgg attatcatgg tactgggcaa cgtatttggt tacaccgtta aagatgccag
     9721 ccccggcaag cacgccgagc acggtaatca actggcggaa atttgccgcc agcccaagcc
     9781 ccgccggacc aaatgacacc gccagcaact taccgactag taacccggca ccaatcttga
     9841 ccagtgtact ggccgccgtc cacaaggacg cttttgccaa cgacatatca ggagaagtag
     9901 ttcaacaaag tcgcaattac cgtacgctga ttgacgggcg acaggttgta gaacagcggc
     9961 aggcgcagca ggcgctcgct ctctttggtg gtgtagcgat cttcaccgtg gaactcacca
    10021 aagtgttccc ccgcagggca accgtgcagc ggaatgtaat gaaacaccgc catgatttcc
    10081 gcttctttca gaaagttaat caacgcgctc cggtcatcaa tatcccgcag tttaatgtag
    10141 aacatatgcg cgttctgcac gcagccatcg ggaatcgacg gcagctcgat acgcccattt
    10201 tttgccagag gcgccagtgc atcgtagtag ttttgccaca gcgccagacg ctgctgattg
    10261 atacgatccg ctgcttccag ttgcgcccac aggtacgctg cttgcagatc ggacatcaaa
    10321 tagctggagc caatatcgcg ccaggtatat ttatcgacct gaccacggaa gaactggctg
    10381 cggtttgtgc ctttttcacg gatgatctcg gctcgttcga tcaacgcttt atcgttaatc
    10441 agcgtcgcgc cgccttcacc acccgccgtg tagtttttgg tttcatggaa gctaaagcag
    10501 ccaatatgac caatggttcc cagcgcacgc cctttgtaag tggacatcac gccctgagcg
    10561 gcatcttcca ccacaaatag attatgcttc ttcgccaacg ccataatagt gtccatttcg
    10621 caggccacac ccgcgtaatg gaccggcacg ataacgcgcg ttttgtcggt gatcgccgct
    10681 tcaatcagcg tttcgttgat gttcatggtg tccgggcgaa catccacaaa gacgattttc
    10741 gcgccacgca gcacaaaggc attggcggtg gagacaaagg tgtagctcgg catgatcact
    10801 tcatcgccag gctggatatc gagcagcagc gccgccatct ccagcgaagc ggtgcaggac
    10861 ggcgtcagta acactttggc gctgccaaaa cgttgctcca gccactgctg gcagcgacgg
    10921 gtaaaaccac catcgccgca cagtttgccg ctacccattg ccgactgcat atagtcgagt
    10981 tcggttccca ccaccggcgg tgcgttaaat ggaatcatgt gatcacctgt ataaccagta
    11041 cgcggtgctt tctacattcg caccactttg tatgtatcgt ttaagcgcgg cggtgttgcc
    11101 catctgggtc gccacccgca aagttgtttt accgcgagca tacgcccagt ttagcgccgt
    11161 ttgcattagc tcagcacctg caccgcgtcc agccagcagg ccaattcgcg catctgtcgc
    11221 attgagttcc cgtaaagaga cataaccgcg aatatcgccg gacgccgcac gtaaaatcag
    11281 acattgatga tcaaaggtgc cgcgcacggc attttcaatc cactgtgcat aaaagcgacc
    11341 gctggcgtca ggcgcatacc acggcgcacg aaaacggctt tgcgcaaatg cggcgctggc
    11401 taactgacgt aatgcgggaa tatcggtctc ttgtgccact actgcaccgc tatcactgac
    11461 attgttcacg ggtagtgcca aatcaacttc accttctatc agggagaatc ccagctgttg
    11521 cagagcatcc agttcacccg tatttgatgc cgcaattttg gcctgcaccc gtgaccacgg
    11581 cgctaaggcg tctggcgtca ggagtgccgc gtcagggcta atacgcacaa tggcgctgtt
    11641 aacaccaaag aaggcgtttt cccaggttag tggctcaata ctggcgcgga cgggcacgaa
    11701 gtaactccag cagatattgg ccgtagccag ttttcgctaa tgaactggca gcacgcttca
    11761 caccctcgtc atcgagccag ccgttacgcc aggcaatctc ttccaggcag gcaatcttaa
    11821 agccctggcg tttttctact gtctgcacaa aagtgctggc ctcaatcagg ctgtcgtgag
    11881 tgccggtatc cagccaggca aatccgcgcc cgagcagttc aacggtcagg ttgcccgcct
    11941 cgaggtacat ctggttgatg gaggtaatct ccagttcacc acgctccgac ggcttcacct
    12001 gctttgcgta ctccacgact ttactgtcgt agaaataaag cccggtcacc gcccagtttg
    12061 atttcggctg ttttggtttt tcttccagcg agatagcgcg gaaattgtcg tcaaactcca
    12121 ccacgccaaa gcgttccggg tccatcacct gatagccaaa taccgtcgcc ccttccgtgc
    12181 gcgccgcaac atgacgcagt ttcggactga agccctgtcc gaagaagatg ttatcgccca
    12241 gcaccagaca agaaggttca ccgttgagga aggtttcacc gatgataaag gcctgcgcca
    12301 ggccgtccgg actgggctgt tcggcatatt ccagctggat accgaactca ctgccgtcac
    12361 ccagcaggcg ctggaaataa cctttatctt ccggcgtagt gatgatgaga atttcgcgga
    12421 taccggccag catcagcacc gacagcggat agtaaatcat tggcttatcg taaatcggca
    12481 acagttgctt agatacgccg cgcgtaatcg gatgcaatcg ggtgccggaa ccgcccgcca
    12541 ggataatacc tttcatgttt gcctccgctg aaaattagcc tttcagacct aaacgctcgc
    12601 cctgatagct gccgtcctgc acctgcttcc accagctttc attagccaga taccactgca
    12661 ccgttttacg cattccactt tcaaaggttt cctgcggcag ccagccaagt tcacgggcaa
    12721 ttttcgaagc atcaatggca taacgcagat catgccccgg acggtcagcg acaaaggtga
    12781 tcaggtcacg atagtgcgcc acgccgtgcg gcttattcgg agccagttct tccagcagct
    12841 cgcaaatggt ttccacaaca tcgagattct tacgctcgtt gtgaccacca atattatagg
    12901 tttcaccgac tttcccggtg gtcgccacgc aatacagcgc gcgggcgtga tcttcaacat
    12961 acagccagtc acggatttgc tgcccgttgc catataccgg cagcggttta cccgccagcg
    13021 cgttgaggat catcagcggg atcagttttt ccggaaagtg gtaaggaccg tagttattcg
    13081 agcagttggt gataagcgtc ggcagaccat aggtccgcag ccaggcgcgc accagatggt
    13141 cgctgctggc ttttgacgcg gaataagggc tgctcggcgc atacggcgtg gtttcggtga
    13201 agaaatcatc cgtcgagtgc aggtcaccat atacttcgtc ggtggagata tgatgaaaac
    13261 ggaacgctga ttttttatct tccgtcagcg cagtccagta agcccgcgcc gcttcaagca
    13321 gtgtataagt cccgacaatg ttggtttcaa taaacgctgc cgggccgtca atagaacggt
    13381 caacatggct ttcggctgcc agatgcatga cacagtctgg ctgatactca gtgaatacgc
    13441 gcgccagttc tgcccgatcg cagatatcaa ctttctcaaa ggcaaagcgc tcgctttgcg
    13501 cgaccggtgc cagcgacatc aggtttccgg cgtaggtcag cgtatcgacc accaccaccg
    13561 cgtcgctcgt ttcgttgatg atataacgca ccagcgccga gccaataaac ccggcaccac
    13621 ctgttatcag aatctttctc atcagcgcca gactcctttg gcatcgacga catactgctg
    13681 atggacgttg tcgccattga taactttgaa ctgactatga tcgaccagca tcaccagcac
    13741 atctgccgtt gccagcgcct cgtcaagctg cgccagagta caaagcccgg tcagtttctt
    13801 cggcaactgg tggatgttag gctcaacaac cagcgtttcg ccgctgtgcc actgggcgat
    13861 cagttcagcg atttccattg ccggactttc gcgcaggtca tcaatattcg gtttaaacgc
    13921 cagaccaaag caggcgattt tcagttcatt ggcgcgttta tcggtagcag ccagacaatc
    13981 agccaccgcc gctttcacct gatcgataac ccagaacggt ttgtgatcgt tcacttcgcg
    14041 cgcggtacgg ataagccgcg cctgctgggg gttctgtgcc acgataaacc acggatcaac
    14101 agcgatgcag tgaccgccca cgccagggcc tggctgaaga atattgacgc gagggtgacg
    14161 attcgccagg cgaatcagtt cccagacgtt aatcccctga tcggcacaaa tcagcgacaa
    14221 ttcattagca aaagcgatat tcacatcgcg gaagctgttt tcggtgagct tacacatttc
    14281 cgccgtccgc gagttagtga cgacacactc accttcgagg aaaattttgt acagttcgct
    14341 ggcgcgggcc gaacaaaccg gcgtcatacc accaatcacg cgatcgtttt taatcagctc
    14401 gaccataacc tggcccggta atacgcgttc cgggcagtaa gcaatgttga cgtccgccaa
    14461 ctcgcccacc tgctgtggga aagtgagatc tggacgcatc tctgctaacc attctgccat
    14521 cttctcggtt gaccccaccg gcgaggtgga ttcaaggatc actaacgcgc cttttttcag
    14581 cactggcgca atggagcgag cagccgattc aacgtaggtc atatctggct catgatcgcc
    14641 tttaaacggt gtgggtacag caatcaacca ggcatccgct tcaactggcg tcgtgctcgc
    14701 tcgtaaaaaa ccgccttcta cggcagtttt tactacgctc gccaaatcag gctcgacgat
    14761 atggatttcg ccacgattga tggtatcaac cgcgtgttgg ttgatatcga caccaatcac
    14821 ctgtttttgc cttgaggcaa acgcagctgc tgtaggcagc ccgatgtaac ccagtccgat
    14881 aacagaaatg gtcgcaaaac tcatagtgat atccgattat tttttaacgc ttccagaatg
    14941 cgagagcatg cctgaccatc accatacggg ttatgggcgc ggctcatagc ttgatattcg
    15001 ttttcgtctt ttaaaagacg cgtcacttcc tcgacaattc gctgcttatc cgtgccgacc
    15061 agacgcaccg tacccgccgt caccgcttcc ggacgctcag tggtatcgcg catcaccagc
    15121 accggtttcc ccagcgaagg cgcttcttcc tgaatgccgc ctgagtcggt caaaatcagc
    15181 caggcgtggt tcatcagcca gacaaacggt aaatactcct ggggatcgat cagaatgaca
    15241 tttttcacat gccccagaat gcgattgacc ggctctctga cgttcgggtt gagatgcacc
    15301 ggatagacaa tctggatgtc ctggtgcgtg gtggcgatgt ctgccagcgc atggcagatt
    15361 tcttcaaagc cacgaccgaa gctctcacgc ctgtgaccgg tcaccagaat catcttttta
    15421 tcggggtcga taaacgggta atttgccgcc agttctgaac gcagcgtatc gctgctcatc
    15481 acctggtcac gcacccataa cagtgcatca atgactgtat taccagtaat gaagattcgg
    15541 ctatccgcaa cgttttcacg cagcaagttt tgccgggaag tttcggttgg agaaaaatga
    15601 tacatcgcca gatgcccggt caatgtacgg ttagcctctt ccggccacgg cgaatagaga
    15661 tcgcccgtgc gcagaccagc ctcaacgtga ccaacaggaa tacgctgata aaacgccgcc
    15721 aggctggttg ccagcgtcgt cgtagtatcg ccgtgaacca gcacgacatc tggtttgaac
    15781 tcggcaagaa taggttttag cccttccaga atccgacagg ttatctctgt aaggccttgt
    15841 cctggctgca ttatgttgag atcgtagtca ggtacaatgg aaaagagttt cagcacctga
    15901 tcgagcatct cccgatgctg cgcagtgacg caaactttag cctcaaaaaa aggatctttt
    15961 gccaacgcat gcaccaacgg tgccatcttg atggcttccg ggcgcgtacc aaatacagtc
    16021 agtactttca catcgattct cttcgaataa gcggcgagcg cctttgcgct caccgcagca
    16081 gtgttgctat ttcgagcaac ggcgggttaa tgcgacacca gccccgatca gtcccccgac
    16141 aatgccccac ataatcatca ggaaggcacg acgtgggcta tcgcgtttta ccggttcttc
    16201 cggcgtacgc aaatagcgat aggtctgaaa acgcggatcc agggttggac caacattcag
    16261 ggtgtttaac atggcccgat tttgatcata gtcgagatca aaggccggac cgacggcctg
    16321 taaattttcc agtcgagcct ggagcattgg acgcccaagc aggaacattt ctgaatcagg
    16381 taattcctcg gcaggcacat ctgtcgcact gcgcgaaata ttatgctgct cagcaatttt
    16441 cagcgcctgt tcaatactgt tcatccggcg gtcatagatg gctttcgcca cctcttcctg
    16501 acgcttcacc tgagctttca tctggatagt gcgtgccgcc catgcgcctt tcagctcatc
    16561 attcagatgg ctggctgcac gctggctggc aaaagcaaca tactgacgta acaggttatt
    16621 agcgtcaggc gcggtttcgg caataagctt cacgctgtca ttgaccgcgc gggtaaagtc
    16681 accgggaata aacacgatgt tgttaatcat ttcatccagc aacgccgcat cggctttgct
    16741 gttgcccacc atccgctgtt tgtaatagtc ggtttgcagc cagaactctc tgcgggtatc
    16801 ccacgaggcc agttgcataa caaactcttt ataagcttcg tccatgaccg atggttggtc
    16861 ggcagaagcc atgtttgaac ggacatccag gttacgcaaa aattgctgct gtgagtagta
    16921 cccgcccagc atattcaccg ttggacgatc ggtaatcgcc gtcgcgctcc actcctgacg
    16981 agcaaaaaaa gtatacgcca gcgcgattaa cgcaaacgcc agccccatgc caataatcca
    17041 tagcttccca gcccacaagg tacgaaacaa cccacgaata tccagttcat tttcagcgtc
    17101 ttcggccggt ttcccaggca ttggttgtgt catcacatcc tcatttattt ggttaaattg
    17161 gggctgccac cacgatttct acgcagtctg cgttttacgc gcttaataaa gcgagcaact
    17221 ttccaggcac gcttgatgca atatccatag aggaagaatg ctagcaaaaa gagcaccagc
    17281 atgacccact ccgggacaaa atgagaatat tctgccagca cgccaatgga agcgagcaat
    17341 gctgcggcaa gggtaatcag cacaaacgcc tggcgggaag taaacccggc acgcatgatc
    17401 aaatggtgaa tatgctgacg gtctggagag aatgggctca tgcctttacg caggcgacgg
    17461 tacataatcg ccaccatatc cattagcgga atggcgataa tccacaaagc ggtaaccggg
    17521 ctgatgggat gagttttgcc ctgggtcgtt tcgagcagga tccagataac ggtaaaacca
    17581 atcagcgtac tgcccgcatc ccccataaag actttgtagc ggcgacccag gataccaagg
    17641 ttaagcatga tgtatggcag gatggcggcg atcatcgcaa agcaccagat tgcgagactg
    17701 gtttgcccgt cgaaccacaa aatcataccg attgctgcaa acgagacgca ggacaacccg
    17761 cccagcaagc catcaatgcc atcaaccatg ttgaacgcat taatggccgc ccagacggca
    17821 aatagcgtca ggaagtaacc aaacggtccg agcaccatct cccaggagcc aaagatataa
    17881 cccaggctac tgagataaag tttgccgaac accatcataa caatgccaac agcggcctgt
    17941 atggtggctc ggatttttac gctgatatca aaacggtcat ccagcgcgcc aatgaaaaca
    18001 agcacaccag cacaagcgag atagagagat gcatgcggaa tatagtagtc gacaattccg
    18061 aacgtgaagc aaatccctgc gtaaaccgaa atccccccaa cgagaggtat caatccctgg
    18121 tgacgtttgc ggaagtttgg tttatccact aaaccgactt tttttgccac cttacgggca
    18181 aaaaacagaa acagtgtcgt gaataaaaaa atactgatga gatcagtact cactgtcagt
    18241 aaattcacaa tgcatgctct cagagaaaat tattagcaga agtataacca cgaagacctt
    18301 tattcagaaa ggaaagtccg ttccgaacct accagcacta tgcgaaaatt aaccacttga
    18361 tatgcaaatt gcataacaca ccagcaaatt ccaggaattt tcctaacatc gccagcgcgg
    18421 cattaagatt acagatataa aagcaaaacg ccacgtaaac acgtggcgtt tttggcataa
    18481 gacaaattta tgagcgtttc atcatttcga agaaatcgtc attggtcttg gtcattgcca
    18541 gtttattaat gaggaattcc attgcatcga tttcgcccat cgggtgaatg attttgcgca
    18601 ggatccacat tttctgcagt tcttcctgag tcgtgagcag ctcttcttta cgggtaccgg
    18661 aacggttgta gtcgatagcc gggaagacgc gtttttcagc gatcttacga gagaggtgca
    18721 gttccatgtt gcctgtacct ttaaactctt cgtagataac ttcgtccatt ttagaaccgg
    18781 tatcgataag cgccgtcgcg ataatggtca ggctgccgcc ctcttccacg ttacgcgccg
    18841 caccgaagaa gcgtttcgga cgatgcaggg cgttggcgtc cacaccaccg gtcaacactt
    18901 tacctgacgc cggaacaacg gtgttgtaag cgcgcgccag acgagtgatg gagtcgagca
    18961 gaatgataac gtctttcttg tgctcaacca ggcgtttcgc cttctcgatc accatttccg
    19021 caacctgaac gtggcgagat gcgggttcgt caaaggtaga agcaacaact tcacctttta
    19081 ccagtcgctg catctcggtt acttcttccg gacgttcgtc gatcagcaga accatcagca
    19141 cacaatccgg gtggttgtaa gcaatgctct gagcaatgtt ctgcagcagc atggttttac
    19201 cggctttcgg cggtgccaca atcagaccac gctgaccacg accgataggt gatgccagat
    19261 ccagtacgcg agcggttaaa tcttccgtag aaccgttacc acgttccata cgcagacgag
    19321 agtttgcgtg cagcggggtt aagttctcaa agaggatttt gttgcgggcg ttttcaggtt
    19381 tgtcgaagtt aacttcgtta actttcagca gcgcaaaata gcgttcacct tctttcggcg
    19441 ggcgaatctt accagagatg gtatcaccag tgcggaggtt gaaacggcgg atttggctag
    19501 gggaaacgta gatgtcatca ggaccggcga ggtaggagct gtctgcggaa cggaggaaac
    19561 caaatccatc ctgcaatatc tccagtacgc catcaccaaa gatatcttcg ccactctttg
    19621 cgtgctgctt caggatggca aaaataatgt cctgcttacg catacgagcc aggttttcca
    19681 gccccatatt ttcgccgaga gtgatcagct cagaaaccgg cgtattcttt aattcggtaa
    19741 gattcatagt ggtgtgagtt cttaaacttg gggtaaatct cgaacttaat gttgtgaatg
    19801 gtatggcagg atcatccatg cctgtttacg gtcatcgact catgtctttt cgctgcctgg
    19861 tcacaggaga gtacgcagaa ctgaaacgac aagacggatt gagtgacgag ccagaaatct
    19921 gttcacttcg catttaagat aaaacgggaa gcgttggaaa ttacaagatt caaacttaat
    19981 aaggtatgtt taatacgaag tcaacactaa gttagcatga ctcacgccgg gcgtccagtt
    20041 tttagcgacg gggcacccga acatgaaatt cccttacgcc aggttagcgt cgaggaactc
    20101 tttcaactga cctttagaca gtgcgcccac tttggttgcc gccacttcac cgtttttgaa
    20161 cagcagcaga gtcgggatac cacggatgcc atatttcggc gcagtgccag ggttttgatc
    20221 gatgttcagt tttgcaacgg tcagtttgcc ctgatattcg tcagcgattt catccagaat
    20281 cggggcgatc attttgcacg gaccgcacca ctctgcccag aaatcgacga ggatcgcccc
    20341 gtccgctttg agtacatccg tgtcaaaact gtcgtcagtc aggtgaataa ttttatcgct
    20401 catatataac tccacaggaa taagcctggc gtgttggttt cgttgttggt gtaacattaa
    20461 ccaactaaag gttgacttta tttcaccgga tacgctttcg taaagcaata gtaagctgat
    20521 attctaccac actatgagca aaacacattt aacagaacag aagttttccg acttcgccct
    20581 gcatccgaag gttgtagaag cccttgaaaa aaaagggttt cataactgta cgcccattca
    20641 ggcactggcc cttccgctga cgctggcggg tcgtgacgta gccgggcagg cgcaaaccgg
    20701 taccgggaaa acgatggcgt ttcttacgtc aacgtttcat tatcttctct ctcatcccgc
    20761 gattgctgat cgcaaggtga atcagccgcg tgccttaatt atggcaccga cgcgtgaact
    20821 tgccgtgcag atccacgccg acgcggaacc gctggcggaa gctaccggcc tgaagctggg
    20881 tctggcttac ggtggtgatg gctacgacaa acagctgaaa gtgctggaaa gcggcgttga
    20941 cattctgatt ggcaccacgg gtcgtttaat tgactacgcc aagcagaacc acattaacct
    21001 cggtgccatt caggtggtgg tgctggacga agccgatcgc atgtacgatc tgggctttat
    21061 taaagatatc cgctggctgt tccgccgtat gccgcctgca aaccagcgcc tcaacatgct
    21121 gttctccgcc acgctttcgt accgggtacg tgaactggcg ttcgagcaga tgaacaatgc
    21181 cgaatatatt gaagtggaac cggaacagaa aacgggccac cgtattaaag aagagctttt
    21241 ctacccttct aacgaagaaa aaatgcgttt gctgcaaacg ctgatcgaag aagagtggcc
    21301 agacagagcg attattttcg ccaacaccaa acaccgttgt gaagagatct ggggccacct
    21361 ggcggcagat ggtcatcgtg tcggtttatt gacaggcgat gtcgcgcaga aaaaacgtct
    21421 gcgtattctt gatgaattta cccgtggcga tctggatatt ctggttgcca ccgacgttgc
    21481 cgcgcgtggt ttgcatattc ctgctgtgac acacgtcttt aactacgatt tacccgatga
    21541 ctgtgaagat tacgttcacc gtattggtcg tacaggtcgc gctggcgcaa gcggtcattc
    21601 catcagcctg gcgtgtgaag agtatgcatt gaatttgcct gctattgaga cctatattgg
    21661 tcactcaatt ccggtaagta aatacaatcc ggacgcattg atgaccgatc tgccaaaacc
    21721 gctgcgcctc acgcgcccgc gcacaggcaa tggtccgcgt cgtactggcg ctccgcgtaa
    21781 tcgtcgtcgt tcaggttaaa gaaaaaatgt catactccaa atcattcaag ctgtatcaag
    21841 atggcaagag aatgaatccc gatgagttta ctgtcgtaag tgattcaggt gaaagaatgc
    21901 agccaacaca gagacagatt gaaggatgaa gagtatgggt tccacctcgt cgctgtatgc
    21961 agccattgat ctcggttcga atagttttca tatgctggtt gtgcgcgagg tggctggaag
    22021 catccagacg ctgacgcgaa taaaacgcaa agtgcgtctg gctgctggcc tgaatagcga
    22081 aaatgccctg tctaatgaag caatggagcg cggttggcaa tgtctgcgcc tgtttgctga
    22141 acgtctgcaa gatatccctc ccccgcaaat tcgcgttgtc gctacggcga cattacgcct
    22201 tgccgtcaat gcgggtgatt ttattgccaa agcgcaggaa atcctcggtt gtccggtaca
    22261 ggtgatcagc ggtgaagagg aagcgcgtct gatttatcag ggcgttgctc acaccactgg
    22321 cggtgccgat cagcgcctgg tggtggatat cggcggagcc agtactgaac tggtaaccgg
    22381 cacgggtgca caaaccacct ctttgttcag cctgtcgatg ggctgcgtta cctggctgga
    22441 acgctatttt gccgatcgta atctggggca ggaaaatttt gatgctgcag aaaaagcggc
    22501 acgcgaagtg ttacgtccgg ttgccgatga attacggtat cacggctgga aagtgtgcgt
    22561 tggcgcttcc ggcaccgtgc aggcgttaca ggaaatcatg atggcacagg ggatggatga
    22621 acgcattacc ctggaaaagt tgcagcaact gaaacaacgc gccattcatt gcggtcggct
    22681 ggaagagcta gagattgacg ggctgacgct ggaacgtgcg ttagtgttcc cgagtggtct
    22741 ggcgatcctg atagccattt ttaccgaact gaatattcag tgtatgaccc tggcgggcgg
    22801 tgcgctgcgt gaaggcctgg tctacggtat gttgcatctt accgtcgagc aggatattcg
    22861 cagccgtacg ctgcgtaata ttcagcgccg ctttatgatc gatattgatc aggcacagcg
    22921 cgtagccaaa gttgcggcta acttcttcga acaggtggaa aatgaatggc atcttgaagc
    22981 aataagccgc gatttgctca tcagcgcctg tcagcttcat gaaatcggcc tgagcgttga
    23041 cttcaaacaa gcgccgcaac acgctgctta tctggtgcgt aacctggatc ttcccggttt
    23101 tacccccgca cagaaaaaac tgctggcgac gctactgctc aaccagacta atccggtcga
    23161 tctctcatcg ctgcatcagc aaaatgccgt accaccgcgc gtcgcagaac aactctgccg
    23221 tttactccgc ctggctatca tttttgccaa ccgtcgccgt gacgatctcg tgccagagat
    23281 gacattacag gctaaccatg aactgttgac cttgacgctt ccgcaaggtt ggctaaccca
    23341 acatccgctg ggtaaagaga ttattgatca ggaaagccag tggcagagct atgtccactg
    23401 gccgctggaa gtgcattaat gagtaagtgc cggatgcgat gctgacacat tttttccggc
    23461 cttgattatt tccctcgttt tgccgccatc atcgctttca gattcgccag atggctttgc
    23521 cctttctgca tccgttcttc ggcgctgacc actttgcgct cctgttccca aatcaaatca
    23581 tcctgcggca gctccagcag gaagcggctc ggctccgggc gcaccagttc gccgtactga
    23641 cggcgttctt tacacagcgt aaaggtcaat tccttctggg cgcgggtaat gccgacatag
    23701 gccagccgcc gctcctcatc aatattgtct tcatcgatgc tgctctggtg gggcaaaaac
    23761 ccttcttcca taccaaccat gtagacatag ggaaactcca gccctttcga cgcgtgcaga
    23821 gtcatcagtt gcacctgatc cagttcttcc tcgctctcgc cgcgctccat catgtcgcgc
    23881 agagtaaagc gcgtcaccac ctgggtgagc gtcatcggct catccagttc gctgccttcc
    23941 agcatctccg tcatccagct aaacagttgg ttgacgttct tcatgcgcat ttcggcagct
    24001 ttcgggctgg gcgatgtttc gtacagccag gattcataat ccatgccgtg gatcagatcg
    24061 cgcaccgcgg caatcggctc ccgctccgcc agacgctgga tttctgccag ccagtgagtg
    24121 aagcgggtca atgcttcata accacgtccg ctaagcgtct gactcaggcc catatcaaag
    24181 ctggcggtaa acatgctttt attgcgcgtc atcgcccatt cacctagctt tttcagcgtc
    24241 gccgggccaa tctctcgctt cggcgtgtta acgatacgca gaaatgcgct gtcatcgtcc
    24301 gggttagtca gcacgcgcag ataagccagc aagtccttga tttcaggacg agagaaaaac
    24361 gacgtaccgc cagatatttt gtacgggatg cggttttgca tcaggaattt ttcaaatacc
    24421 cgcgactgat ggttgccgcg ataaagaatg gcgtaatctt tgtactgcgt tttattgacg
    24481 aagtgatggg cgatcagctc gccggtgacg cgctcggctt catgttcctc gttattcgcg
    24541 cttaaaactt ttagctctgt gccgtaaccc agttcggaga acagacgctt ttcaaagacg
    24601 tgcgggttat tggcgatcag gatgttcgcc gctttcaaaa tacgtccgga agagcggtag
    24661 ttctgctcaa gcttaatcac cttcagcgcc ggaaaatcct ggctcagcag caccagattc
    24721 tgcggacgtg cgccgcgcca ggagtagatc gactggtcat cgtcacccac cacggtaaag
    24781 cgcgcgcggc tgcccaccag cagtttcacc agttcatact ggctggtgtt ggtgtcctga
    24841 tactcatcca ccagcaggta gcgaattttg ttctgccagc gctcgcggac ttcttcattg
    24901 cgttgcagca gcaacgtcgg caataaaatc agatcatcga agtcgagaac gttacaggct
    24961 ttcaggtgtg catcatacag cccataacaa tgggcaaaaa tacggtcccg ctcgcccttt
    25021 gcctctgccg ccgcctgcgc cggtgttttg agatcgttct tccagttgga gatggtcgaa
    25081 attagctgtt gcaggagaac tttgtcatct tcaatcagcc cctcggtcaa ctctttaagc
    25141 aaagcaagct gatcggtatc gtcaaacagc gaaaagttag ccttcatccc cagcgccgca
    25201 tactcgcgtt tgatgatatc cagccccagc gtgtggaagg tggaaatcat cagcccacgc
    25261 gcctctttgc gccccagcgt ctgcccgaca cgctctttca tctcgcgtgc cgccttattg
    25321 gtaaaggtca cagccgcgat atgtcgcgcc tgataaccgc aaccgcggat cagatgggcg
    25381 attttattgg tgataacacg agttttaccg gaacccgcgc ccgccagcac caggcagggg
    25441 ccggtaacga attcgacagc ttgttgttgg ccggggttta gacgcatagg aaaatcgctc
    25501 aatgaaagtc gggaggggaa aataacagcg tggtagtata gccagcctca tccttaccac
    25561 tcaaggcacg atcatggcaa aaacagcagc agcactgcat atccttgtaa aagaagagaa
    25621 actggctctg gatcttctcg agcagatcaa gaatggtgcc gatttcggca agctggcgaa
    25681 gaaacactcc atttgcccgt caggcaaacg cggcggtgat ttaggtgaat tccgccaggg
    25741 tcagatggtt ccggcgttcg ataaagtggt gttttcttgc ccggtgctgg aaccaaccgg
    25801 accgctgcat acccagttcg gttaccacat cattaaggtg ctataccgta attaacagca
    25861 aggccttctc cgggagaagg ccttgaactc tgaatcgcta ttaacccgca acagcaatgc
    25921 gtttcatatc tgtcatatag ccgcgcagtt tcttacctac ctgctcaatc gcatggctgc
    25981 gaatcgcttc atttacatca cgcagctgcg cgttatctac cgcaccttcc ggaatagctt
    26041 tacccaggtc gcccggttgc agctctgcca taaacggttt cagcagtggc acacaagcgt
    26101 aagagaacag atagttaccg tactcggcag tatcggagat aaccacgttc atttcgtaca
    26161 gacgcttacg ggcgatggtg ttggcaatca gcggcagttc gtgcagtgat tcatagtaag
    26221 cagattcttc gatgatgcca gaatcaacca tggtttcaaa cgccagttca acgcctgctt
    26281 ttaccatcgc gatcatcagt acgcctttat cgaagtactc ctgttcgccg attttgcctt
    26341 catactgcgg cgcggtttcg aatgcggttt tgccagtctc ttcacgccag gtcagcagtt
    26401 tcttatcgtc gttggcccag tcagccatca tgccggagga gaattcgccg gagatgatgt
    26461 cgtccatatg tttctggaac agcggcgcca tgatctcttt cagttgctca gagagcgcgt
    26521 aagcacgcag tttcgccggg ttagaaagac ggtccatcat cagggtgatg ccgccctgtt
    26581 tcagcgcttc ggtgatggtt tcccaaccga actgaatcag tttttctgcg tatgccggat
    26641 cggtgccttc ttccaccagc ttgtcgaagc acagcagaga gccagcctgc aacataccgc
    26701 acaggatggt ttgctcgccc atcaggtcag atttcacttc cgcaacgaaa gaggattcca
    26761 gaacgcccgc acggtgaccg ccggttgcag ccgcccaggc tttagcgatc gccatgcctt
    26821 cgcctttcgg atcgttttcc gggtgaacgg caatcagcgt cggtacgccg aatccacgtt
    26881 tgtactcttc acgtacttcg gtgccagggc atttcggcgc aaccattacg acggtgatgt
    26941 ctttacggat ctgctcaccc acttctacga tattgaaacc atgagagtag cccagcgccg
    27001 cgccgtcttt catcagcggc tgaacggaac gcactacgtc agagtgctgc ttgtctggcg
    27061 tcaggttaac caccagatcc gcctgcggga tcagttcttc gtaagtgcca actttgaagc
    27121 cgttttcggt tgctttacgc caggatgcgc gcttctcggc aatcgcttct ttacgcagag
    27181 cgtaggagat atcgagacca gaatcacgca tgttcaggcc ctggttcaga ccctgtgcac
    27241 cacagccgac gatgactact tttttaccct gaagatagct cgcgccatcg gcgaattcat
    27301 cgcgccccat aaagcgacat ttgcccagct gtgccagctg ctggcgcaga ttcagtgtat
    27361 tgaagtagtt agccatggtg attcctcgtg atgttgtgct tcttattgtt cggttcgcgt
    27421 ttgcgagatt gaattcacta tatgacagga aatttattgc ggaaattgat atattcacaa
    27481 cgtcacattg caatttctgc aacgtcaaca ttaagggctg cgccattgga tttacgcgat
    27541 ctgaaaacct tcctgcatct ggcggaaagc cgccattttg gccgcagcgc gcgggcaatg
    27601 cacgttagcc cgtccacgct ctctcggcag attcagcgcc tggaagacga tctcggtcag
    27661 ccgctgtttg tgcgcgataa ccgcacggta acgctaaccg aagcaggcga agaactgcgc
    27721 gttttcgccc agcaaacgct gttgcagtat caacagctgc gccacaccat cgatcagcaa
    27781 ggaccgtcgc tctctggcga attacatatc ttctgctcgg tgaccgctgc ctacagccat
    27841 ctgccgccga ttctcgatcg cttccgcgcg gaacacccgt cggtggagat taaactcacg
    27901 actggtgatg cggcagatgc gatggaaaag gtcgtcactg gcgaagcgga tctggcgatt
    27961 gccgggaaac cggagactct gcccggcgca gtggcgtttt cgatgctgga gaatctggca
    28021 gtagtgctga ttgcccccgc gctaccctgc ccggtgcgta accaagtttc ggcagataag
    28081 ccggactggt ctacagtgcc gtttatcatg gccgatcagg gaccagtacg ccggcgcatt
    28141 gagttgtggt ttcgacgcaa caaaatcagc aacccgatga tttacgccac ggtcggcggg
    28201 catgaagcga tggtgtcgat ggtggcgctc ggctgtggcg tagccttgtt gccggaagtg
    28261 gtgctggaaa acagcccgga accggtgcgt aaccgcgtga tgattttaga gcgcagtgat
    28321 gagaaaacgc cgtttgaact gggcgtgtgt gtgcagaaaa agcggctaca tgagccgctg
    28381 attgaggcat tctggaagat tttgccgaac cattaacccg ccaaaaagaa cctgaacgcc
    28441 gggttattgg tttcgtcgtg gcaatcgtaa cccaactcat tcaaccgggt ttcgaaatcc
    28501 ggttcatggt cgccaagttc gaacgccgcc agtacgcgcc cgtagtcggt gccatggctg
    28561 cgatagtgga acaaagaaat gttccagtgc gtacccagcg tgttgaggaa gcgcaacagc
    28621 gcgcccggcg attccgggaa ttcgaagctg tagaggcgtt cctgcaacgg atgcgacgga
    28681 cgcccgccga ccatatagcg cacatgcagc ttcgccattt cgtcgtcgga gagatccact
    28741 acgctgtagc cgccatcgtt gagcatctgc aaaatttctt tgcgctcttc gaggccacgg
    28801 ctcaggcgca caccgacaaa gatgcaggcg tttttggcat cggcaaaacg gtagttgaac
    28861 tcggtgaccg agcgcccgcc aagcagctgg cagaacttca ggaagctgcc cttctcttcc
    28921 gggatggtta ccgccagcaa cgcttcacgc tgttcgccca gttcgcaacg ttccgagacg
    28981 tagcgcaggc cgtgaaagtt cacgttagca ccagaaagaa tatgcgccag ccgctcaccg
    29041 cgaatgttgt gctgggcgat atattttttc attcccgcca gtgccagcgc gccagagggt
    29101 tccgctaccg cgcgcacatc ttcgaacagg tctttcatcg ccgcacatat ggcatcgcta
    29161 tcgacggtga tgatgtcgtc gagatactcc tggcataaac ggaaggtttc gtcgccgatg
    29221 cgtttcaccg caacaccttc ggcaaacagc cccacgcgtg gcagatcaac cggatgacct
    29281 gcatccagcg ccgctttcag gcaggcggag tcttccgctt ccacggcaat cactttgatt
    29341 tgcggcatca gttgtttgat cagtaccgcc acgcccgccg ccagaccgcc gccgccgact
    29401 ggcacaaata cgcggtcgag atgggcgtcc tgctggagca gttccagcgc cagcgtgcct
    29461 tgcccggcga tcaccatcgg atggtcgaac ggcggcaccc aggtgaagcc ctgctgctgt
    29521 gacagttcga tcgctttcgc ttttgcttca tcaaagttcg cgccgtgaag aagcacttcg
    29581 ccgccgaagc cgcgcaccgc gtcgactttg atatcggcgg tggcggttgg catgacgatc
    29641 agtgccttca cgcctaaccg tgcggaagaa aacgcgacgc cctgcgcgtg gttacccgca
    29701 gaagcggtga tcacgccgtg cgctttctgt tcttccgtca ggcccgccat catggcgtat
    29761 gcgccgcgca gcttaaagct atgaactggc tgacggtctt cgcgtttcac cagaatcacg
    29821 ttatcgagac gcgacgagag tttttccatt ttttgtagcg gcgtgacctg cgccgcttcg
    29881 tagaccggcg cgcgcagcac cgctcttaaa tattcggcgc cttccggggc gccggagaga
    29941 ggttgtgagt ctgccatcat taacccccca gtttcgattt atcacgcacc gcgcctttgt
    30001 cggcgctggt tgccaggctg gcgtaggcac gcagcgcaaa ggaaacctga cgttcacgat
    30061 ttttcggtgt ccaggctttg ttgccacgag cttcctgcgc ttcacgacgc gccgccagtt
    30121 cggcatcgct tacctgtaac tgaatgccac ggttcggaat gtcgatagcg atcaagtcac
    30181 catcttcaat caggccaatg ctgccgccac ttgccgcttc cggtgagacg tggccgatgg
    30241 aaagaccaga ggtgccgcca gagaaacgac cgtcggtgat cagcgcacag gctttaccga
    30301 gacccattga tttcaggaaa ctggttgggt agagcatttc ctgcatcccc ggaccgcctt
    30361 tcgggccttc atagcgaatt actaccacat ctccggcgac aactttaccg ccgagaatcg
    30421 cttctaccgc gtcgtcctgg ctttcgtaga ctttcgccgg gccagtgaat ttgaggatgc
    30481 tgtcatcgac gcctgcggtt ttaacgatgc agccgttttc tgcgaaatta ccgtagagta
    30541 ccgccaggcc gccgtctttg ctgtaagcgt gttccagcga gcggatacag ccattggagc
    30601 gatcgtcgtc cagcgtatcc cagcggcaat cctgcgagaa tgcctgtgta gtacgaatgc
    30661 ccgccgggcc agcgcggaac atatttttta ccgcatcatc ctgggtcaca atgatgtcgt
    30721 attgttccag cgtttgcggc aacgtcaggc caagtacatt tttcacatca cggttcagta
    30781 accccgcacg atccagctcg ccgagaatac cgataacacc accagcacgg tgaacatctt
    30841 ccatatggta tttttgggtg ctcggcgcga ctttacacag ctgcggtact ttgcgggaga
    30901 gcttatcgat atcactcatg gtgaagtcga tttccgcttc ctgcgccgcc gccagcaggt
    30961 gaagaacggt gttggtagag ccgcccatcg cgatatccag cgtcatggcg ttttcaaacg
    31021 ccgccttact ggcgatgtta cgcggcagtg cgctttcatc atcctgttcg tagtaacgtt
    31081 tggtcaattc aacaatgcgt ttaccagcat tgaggaacag ttgcttgcga tcagcgtggg
    31141 ttgccagcag cgagccgttg cccggctgcg acaggcccag cgcttcggtc aggcagttca
    31201 ttgagttagc agtaaacatc ccggagcagg aaccgcaggt tgggcaggcg gatcgttcaa
    31261 cctgatcgct ctgggagtca gaaactttcg ggtctgcgcc ctggatcatc gcatcaacca
    31321 gatcgagctt aatgatctga tcggacagtt tggttttccc ggcctccatc gggccgccgg
    31381 aaacaaagat caccggaata ttcaggcgca gggaagccat cagcatcccc ggggtgattt
    31441 tgtcgcagtt agagatgcag accatggcgt cggcgcagtg ggcgttgacc atatattcaa
    31501 cggaatcagc gatcagttcg cgagatggca gtgaataaag catgcccccg tggcccatag
    31561 cgatcccatc atccaccgca atggtgttga actctttggc aacgccgccc gccgcttcaa
    31621 tttgttcggc gaccagttta ccgagatcgc gcagatgaac gtgacccggt acaaattggg
    31681 tgaacgagtt cacaaccgcg ataatcggct taccgaaatc ggcgtcggtc attccggtgg
    31741 cgcgccacag cgcacgagca cccgccatat tacgaccatg agtggtggtg gcggaacggt
    31801 acttaggcat actttattta ctcccagtgt ctgtctcgta aatgggacgg tgcgtgccgt
    31861 cccatttttt gtatttattg attaacttga tctaaccagc cccatttatc ttcggtctcg
    31921 ccagtgaaga ggccgaagaa ggcttgctga atgcgtttgg taaccgggcc gcaacggcct
    31981 tcaccaacct gaataccatc tacactgcgc actggcgtga tttctgccgc cgtaccggac
    32041 ataaagactt catccgccag gtacagggat tcgcgcgaca gcacctgctc acgcacttca
    32101 attcccagct ctttcgccag tttgatgatg gcatcacggg taatacccgg cagcgcggag
    32161 gaggtgaacg gtggagtaaa cagcacaccg tctttcactt caaacaggtt ttcgcctgcg
    32221 ccttcagaga tataaccatt cacatccaac gcgatacctt cctgataacc gtggcggcgc
    32281 gcttcgctac ccaccaacag ggaagagagg tagttaccac cagctttcgc tgcggttggg
    32341 atggtgtttg gtgcagcacg gttccaggag gaaaccatcg catcgatccc ctgctccagc
    32401 gcttctgcgc ccagatacgc cccccacggg aaagcggcga taatcacatc ggttgagtat
    32461 cccgctggcg ggtttacgcc catgccaaca tcaccgacga aaatcagcgg acggatatag
    32521 gcgctggtga gattgttttt gcggatcacg tcgcgacaag cttccatcag ctcatcaatg
    32581 ctctgcgaaa ccgggaaacg atagattttg gcggagtcat gcagacgctg catatgctca
    32641 cgatggcgga atacaaccgg tcctttgtgc gagtcgtagc aacggatgcc ttcaaaaacc
    32701 gaggtgccat agtgcagcgc gtgcgacatc acatgcacct tcgcgtcttc ccagcgaacc
    32761 atctccccat tgaaccaaat gtaatcagct ttcttcgtgg tcatttttat attccttttg
    32821 cgctcaggcg cggatttgtt gtgatgtggt tgtgctctgg cagatagcaa cgtgtgcgac
    32881 gtccaccagt ttatttaact gactaaacag taagtcgacc gaccgtgggc tggcaacggt
    32941 caattcgata tttatatttt gtgcatcgct ggcggcagcc atattcattg agcagacgtg
    33001 gaaaccacga tgacgcacca cgcgtaaaac acgttctaag gtttccggat tgaagcgagc
    33061 cgatacattg acctgatgtt gcatcatgat aatttctcca acatttcaga attactggca
    33121 ccaggcggca ccagcggcca gacgttctca agttcgtcga ttgagacatg aagcaggtat
    33181 ggcccatcac tgttcagcat ggtgtcgagt gccgcttcaa cctggtcttt atgggtgatg
    33241 tgttggccag ggatgccgaa ggcgctggct aacatgagga aatcggggtt atcggtaagg
    33301 gtggtttcgc tgtatcgttc ctggaaaaac agttgctgcc attgtcgaac catccctaac
    33361 cgttggttat cgagtaagac gattttcaac ggtaactgct tgcgttttac ggtgcccagc
    33421 tcttgcacat tcatcataaa agagccgtca ccggagatac agacgacagt atcgttcggt
    33481 cgcgcgactt gtgcgccaac cgccgccggt aaaccgaaac ccatggtgcc taagccgctg
    33541 gaggtgatga agttttccgg gcgagtgtgg acgatgtgct gggcagccca catctggtgc
    33601 tgccccacat ctgtggtcac gatgcaatcc gcaggtttac gatccgacag ttgttttaac
    33661 aacaacggcg cgtagatagc gtcaccagga tggtcgtaac gccaggcatg ttcatcacgc
    33721 agttgcgcgc agtgttgctg ccagtcatcg atatttaacg gctgctgtaa tgctggtaac
    33781 agagcattta aatcaccctg taatgccaca tgtgcctgac gcagcttgtt catttctgcc
    33841 ggatcgatat ccatatggat aacgctggcg tgtggtgcga aggtgttcag tttgccggtc
    33901 acccggtcat caaaacgtgc gcccacggct atcagtagat cgcactcctg cactgcgaag
    33961 ttcgccgctt tggtgccgtg catccccagc atgcccagat agtacggata atctgcttct
    34021 actgcgccca gccctttcaa cgtacaggtg gcaggcattt ttgtggcagc gagaaattca
    34081 cgcaaagccg aaactgcctg cgccatgccc acgccaccgc caacgtacag catcggtttt
    34141 tgcgcttttg ccagcatctg acgcgcttgc tcgacttcgg catgtgggaa agtcacttcg
    34201 ttttcaacag tggtgaacca cggttccaga tcgccgctgg ctaactggat atcttttgga
    34261 atatcgacca aaaccggacc aggacgacca gagctggcga cgtcaaacgc ttcggccatg
    34321 atacgcggta actcttccag tgattgcacc aggaaactgt gcttggtgca ggctaacgac
    34381 aaccccagaa tatccacctc ctgaaatgcg tcagtgccga taaacggtgc ggatacctga
    34441 ccggtgatag caacaacggg gatggaatct aacagcgcgt ccgcaagccc ggttatcagg
    34501 ttggttgcac ctgggccaga cgtggcgatg caaacgccag ttttgccggt agcacgggca
    34561 taaccgatag ccgccattgc tgcaccttgc tcgtgtcggc acagcaagtg ttccacgcca
    34621 ccgtcataca atgcatcgta aaccggcata attgcgccac ccggataacc gaaaacggtg
    34681 tttacaccct gtgcccgcaa cgcatgtacc acccactgtg caccattcat agttagttcc
    34741 ccgtcctgaa tcttgagaaa cagaattttg tgctgttatt cattgtctgc tcctcagtta
    34801 tgtttttaag gtcaaaaaaa acccccggac ctttcggtgc gggggtctta gttcgttaag
    34861 gcttgatctc taagcctttc ctcgtccaag tgcagccccg catggtggga taataatcac
    34921 caccacgcta atcacgacca ggctaatcac tcgtagaagg gctgtcattt tgtcttttct
    34981 tgcatcttgt tcgaaggaat gcctaaagag ttaccataga ttttgcgaat agcacaagat
    35041 attttttggc cgatttttat gatgtcttta ataatctcaa gagaaattgt tgttttttaa
    35101 aaagaaaata gtgagtgaaa aaaattcaat ttcagtatga atgttgttcc cttcctcgta
    35161 gttcatcctt tgcccgctgc atttttgcga gcatcattcc accgccagaa caactcaact
    35221 tcacttgcac aaataaacag gaatcagcca ctaaaattca cgaatttgcg ggctacagca
    35281 gcgatatctt atgcacataa tggtgactca aggagggctt atgtcactgt caattgttca
    35341 tacccgcgca gccctgggag taaatgcgcc cccaatcact gttgaggtac atatcagtaa
    35401 aggtctacca ggcttaacga tggtgggctt accagaaaca acggtaaaag aagctcgcga
    35461 tcgcgtgcgc agcgccatta tcaatagcgg atatgaatat ccggcgaaaa aaatcaccat
    35521 caaccttgct ccagccgatc tgccaaaaga agggggacga tatgatttgc ctatcgctat
    35581 tgcgttgctg gcggcctcag aacagcttac agccaataag ttagatgaat atgaattagt
    35641 cggagaactg gcgcttacag gcgctctgcg tggcgttccc ggcgcaatct ccagtgcaac
    35701 tgaagctatt aagtcgggca gaaaaattat cgtcgcgaaa gataacgaag atgaagtggg
    35761 gctaattaac ggtgaaggat gcctgatagc cgatcatctg caggctgtct gcgcgtttct
    35821 ggaaggtaag cacgctctcg aacacccgaa accaactaat gcagtatccc gggcgctaca
    35881 acatgatctc agtgatgttg tcggtcagga gcaaggaaag cgaggactgg aaattaccgc
    35941 cgctggcggg cacaaccttt tactgattgg accgccggga acaggtaaaa caatgctcgc
    36001 cagccgtatt aatggccttt tgccagattt aagcaatgaa gaggcactgg agagcgctgc
    36061 gatattaagt ctggtaaatg ctgaatcagt acaaaaacaa tggcggcaac gcccgttccg
    36121 ctcacctcat cacagtgcgt cgttaactgc gatggtgggc ggtggtgcaa ttccagggcc
    36181 aggtgaaatt tcgctggcgc ataacggcgt gctttttctt gatgagctac ctgaatttga
    36241 acggcgtaca ctggatgcct tgcgagagcc gattgaatcc gggcagatcc atctttcacg
    36301 cacacgagca aaaataacct atccagcccg tttccagctt gtcgcggcga tgaatcccag
    36361 ccctaccgga cattatcagg gaaaccataa ccgctgcaca ccagaacaga cattacgtta
    36421 tctcaaccgg ctctcggggc cctttctcga ccgcttcgat ctctcactgg agatcccatt
    36481 accgcctccc ggcattttga gtaaaacggt agtgccggga gaaaacagca ccaccgttaa
    36541 acaacgtgta atggccgcca gagagcgcca atttaagcgg cagaataaac tgaacgcctg
    36601 gctggataat ccggaaatac gccaattctg caagcttgag agcgaagatg cgcagtggct
    36661 ggaagaaacg ctgatccatc tggggttatc gattcgtgcc tggcagcggt tattgaaagt
    36721 tgcacgaacc attgctgata ttgatcagtc tgacattatc acacgtcagc atttgcagga
    36781 ggcagttagc tatcgtgcga ttgaccgttt gctcatccat ctgcaaaaac tactgacata
    36841 aaaaaagggc atttcgccct ttttattaat cgtcagaatc ggtgtagtct tcagcacctt
    36901 caacctgcgg tttaccgccg gaaagggtgt gaaaacgttt tggacgcttg atacgcgtca
    36961 tatacttgga ccacacgcgt tctgcttctg tcactggttc acgttcgcca cggcatactg
    37021 ctacgaagag tttctcttcc tcggtaaccg gctcgcgttt gccaagatcc aactcattga
    37081 aggcataacc atgacgctca agcagttgtg cctctttgat ggtgaagtca ccatgacgag
    37141 agaatccacg tggataatgt ttattgtcga aatatcgatt agtcgtcgta aagctttccg
    37201 ccatcctgca cgctcctaat tctttgaccg agctagttat ggcgcggagt attagttacg
    37261 cttgacagag tgtaaaacaa aacatttaaa tcataacgac aaataatttt gcggagagca
    37321 ctgtggatac ggaattgtta aaaactttcc tggaagttag ccgaacgcgt cactttggtc
    37381 gagcggctga atcgctctat ctgacccaat cagccgtgag ctttcgaatc agacaactgg
    37441 aaaatcaact gggtgtgaat cttttcaccc gccacagaaa caatatccgt ttaaccgctg
    37501 ccggagaaaa gcttctgcct tatgcagaaa cgctcatgag cacctggcag gccgcccgca
    37561 aggaggtggc gcatacctca cgacataatg agttttctat cggtgccagc gcctcgctgt
    37621 gggagtgtat gcttaatcag tggctgggac gcttgtatca aaatcaggat gtccatacag
    37681 gcttacagtt cgaagcgcga attgcccaac ggcagtctct ggtaaaacag ttgcatgaac
    37741 gccagcttga tcttcttatt acaactgaag cccccaaaat ggacgaattt tgtagtcagt
    37801 tgctggggta tttcacttta gcgctttata ccagtgcccc ttctaaacta aagggagatc
    37861 ttaactatct gcgactagag tgggggccag actttcaaca gcatgaggca ggtttgatcg
    37921 gtgctgacga agttcccatt ctgacaacca gttctgctga actggcacag caacagattg
    37981 cgatgcttaa tggttgcacc tggctacccg tcagttgggc acgtaaaaaa ggcggcctgc
    38041 ataccgttgt cgatagcaca acactttcac ggccgcttta tgccatatgg ctacaaaata
    38101 gcgataaaaa tgcgttgatt cgcgatctat tgaaaattaa cgtgctggat gaagtgtatt
    38161 aatctgaatg gctggcaagg atgccggtag aaggatttac ttcggagagg gttatttcag
    38221 ataaaaaaaa tccttagctt tcgctaagga tgatttctgg caggggcgga gagactcgaa
    38281 ctcccaacac ccggttttgg agaccggtgc tctaccaatt gaactacgcc cctaattagg
    38341 gtggcggaac ggacgggact cgaacccgcg accccctgcg tgacaggcag gtattctaac
    38401 cgactgaact accgctccac cgaattcttt tacaaccacc ggttttatga ccggcttact
    38461 gcttaatttg atgcctggca gttccctact ctcgcatggg gagaccccac actaccatcg
    38521 gcgctacggc gtttcacttc tgagttcggc atggggtcag gtgggaccac cgcgctaagg
    38581 ccgccaggca aattctgttt tatcaacacg tcccgttatg acctgttgat tcaatctg
//
LOCUS       DAFGPF010000037        38243 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFGPF010000037 DAFGPF010000000
VERSION     DAFGPF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38243
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.037"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            237..629
                     /locus_tag="LSX49_002116"
     CDS             237..629
                     /locus_tag="LSX49_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2787 family protein"
                     /protein_id="HBL7168523.1"
                     /translation="MPVDQELINIILNEAGNPPPHKAKITAVSLLFKDLSYSAEKGGY
                     HPVEIRIISRNDEWYFDYITDFSYMGTVYPELEKEIDISWSQQYVFLAYVGDLPVNAG
                     RELFELWQSNFIQYHGMNIYTITVLWES"
     gene            749..1210
                     /locus_tag="LSX49_002117"
     CDS             749..1210
                     /locus_tag="LSX49_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168524.1"
                     /translation="MLSWLYDGRVKRRPLMNWLIQTYQQRWPLHEWLTEGIEEDRLDW
                     LIAQVLQKGHYRRQFPVEITRPFAGKRGLTDGRLFREMQRFLDVTDHSRLIMLSDQFH
                     WSLLVKMDEEMLCFFDSNGRTTMPRKAFSLRTGVTRRQLFPDAIYFIEREF"
     gene            1212..1664
                     /gene="radC"
                     /locus_tag="LSX49_002118"
     CDS             1212..1664
                     /gene="radC"
                     /locus_tag="LSX49_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL7168525.1"
                     /translation="MTMFTQRETRILDQARDIISRYYQRGVQLCSPDDVRRCVMVELA
                     PLEHEEFGIILLDNHNQLLHREILFRGTLNSVSVHPREVIKRVLKHNAAAVILVHNHP
                     SGEPEPSRCDIQLTKKLQELLEILDVRLLDHFIVAGTETVSMAERGLV"
     gene            1711..2640
                     /locus_tag="LSX49_002119"
     CDS             1711..2640
                     /locus_tag="LSX49_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019083242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL7168526.1"
                     /translation="MSRTALRQVVPVVQTTVFDAYIVGLAPSGRRGITSLLNRSASIL
                     KHGADAADYPWEQLNYAAVAKVRAALLDDGYAVSSVNMALSALRGVAQTAFNLNYMDA
                     ETLARIRSVKRVSGDVQRKGRALGRQEIRVLIQAAKQHPQSVRRCRDVAIVLMLCGTG
                     LRAGELVKLERRDYDNGILTVRQGKGRKYREIHVADAVDKAIRAWLKVGADEADSALF
                     RRIQRSGKVASQPLTTTGLTGILAELQQTAGIARFTPHDMRRTFITRLLEQGVDINTV
                     RQLAGHSDISTTTRYDCRGDTMKISASKRIRCF"
     gene            complement(2627..3241)
                     /locus_tag="LSX49_002120"
     CDS             complement(2627..3241)
                     /locus_tag="LSX49_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168527.1"
                     /translation="MIGNQSNKADARCHRERKSSNEVFEFLEKKLYLGRDTRQKLALI
                     ARKLTGAGFSPDKFAAEKAADVLSACVNHMFNDLLNEGEPNGIYRPEEHPMIVPARSP
                     KALEIYTVYQLVKGRFDKLHTGESDREKYASVAEKLNEYGIWKPRLKRLSDGKEWARE
                     DVAWMLQPENINAQINIQNQKYARLSAEDETETESGNASTAKNI"
     gene            3464..3661
                     /locus_tag="LSX49_002121"
     CDS             3464..3661
                     /locus_tag="LSX49_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HBL7168528.1"
                     /translation="MNTNRILRKKEVLHLTGNSSATLYRLISKGFFPLSKRLTGDNGR
                     AVGWLESDINNWVNSRMQAGE"
     gene            3663..4130
                     /locus_tag="LSX49_002122"
     CDS             3663..4130
                     /locus_tag="LSX49_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168529.1"
                     /translation="MKEIKSKTSSAKKTLVPWFETMGKQVGLSQETISAVLKEQRLRI
                     RKLNYASAYTVSNILIQDCGGADDMWSNYAKLALILERCKYIPCGSRACAYCSTAQQL
                     HYQGVDVTGEYALYQLPELFLDFLETNDKNSSYHWDYNKLVERHEDAQARSFG"
     gene            4218..5072
                     /locus_tag="LSX49_002123"
     CDS             4218..5072
                     /locus_tag="LSX49_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168530.1"
                     /translation="MNDSYYFRTSDPDYIRHAPSMLEILSKAFPTIITQQESEYELQR
                     LNHLLNKLKGSNRCYNIIAQKLRQCRNGSPCNSLICPHCQRERILAQLAMLHVLPGNS
                     AEYVGVVLFFNKDTQTPPPWKNIGALRAQIGRYKQRISRVLNRLGYAGPATGTFSMMR
                     HMPDGPEERIFWVPQLCLFLPNDSTLIKGLKAHMSRSGGAFIDASTLNTPVIVLRYKD
                     PARLISCALNPVWHTADYTLTDKDALVKSRMELLKGRTLLKSLLTLDSLGTGVVSFSF
                     GQPPGKVH"
     gene            5673..7046
                     /locus_tag="LSX49_002124"
     CDS             5673..7046
                     /locus_tag="LSX49_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168531.1"
                     /translation="MKIPKWVYDRITEITDYVVGDTQWAVTRRQTVRWFLAHIWLETD
                     DDGWTICTVRDIRSSYASLLGQCEISYQGECFMSTLTDFLPTLSDIEFRAGKASKDPE
                     KRRASAWRFNPLLPVCDESARGKLNLVDLDTGESVSFRALLQGNGKAPGHAIDVEKRQ
                     TALKQTEKDFLAKVGRGRMSIQFVKELRSREPDHYYRAGIRSLNHLYNGRIEGQYVTY
                     DHHYRLTFGGRYYDQAFQNLPNEFKAKFRTGLLNYDIEACNLACLNHLFRQYDVDYRV
                     KSSIYKTMMEHTGLTRKQCKQMVHTTTYRIGRVTIGVNDGLGAKVYGWCGNSKKKALK
                     ILRWWNRYISPLKSALESLLERVHGAHRKSCSSPRNYHRYANEVGLILDLNSEVYQRE
                     KTHHHQYARNKALLAFMICGVEQAYIREVVSMNPGRVCMLDHDGVVATGALSLPDWRG
                     FTMKVKD"
     gene            7224..7848
                     /locus_tag="LSX49_002125"
                     /pseudo
     CDS             7224..7848
                     /locus_tag="LSX49_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830285.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            8043..10700
                     /locus_tag="LSX49_002126"
     CDS             8043..10700
                     /locus_tag="LSX49_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2339 domain-containing protein"
                     /protein_id="HBL7168532.1"
                     /translation="MDELLTLGCIALFFALVVVPILAIIALSRSTAVRSELATLRRRV
                     EVLEQRGVTEAPATVVTTVPQSVSQMVVPVETSSPAVNIVLSEPVADVTPESVDPWRP
                     QPKPQNEALPTPAVEQSSAFGGVMSSLVRWFMQGNPLAKLGILLLFLGFSFLLRYTVE
                     HSLFPLELRLVATSLFAIALLVVGWRLRHKQLVYALIIQGGATGTLYLTVFGAFWLWQ
                     MLPMTLAFALLVAICAASVGLAIMQKALSLAMLASIGGYLAPLLLSTGGGSHVALFSF
                     YLLLSVGILAISIWQHWRELNLLGLLFTFGIGGLWGLDGYRSEYYLSSQLFLIANTII
                     FGVLSVALSLRAQEKGKQIIDGVLLFASPLVGFGMQYAITRHMEYGPALSALGYGGFY
                     LALAWLALRRYPSLGRPLVLAALALGGAFTTLAIPLALSARWTAMAWALEGLGILWLG
                     VQQQQRRMSYSGTALLVLAVCSALWAQMNGMSALSLVLIFAVLSLSWLAAAWLWRNIQ
                     LQGSWVLLAGGLIFWIIALIGASQLVLKKDSLVLSGVLALMAISVWGWRIVSGRLAWW
                     ELDVSKWLLWPTMLVMLLSQISQHEIFAAGWQNLAWCLALPAAGALLWRDAETLPPRL
                     SRLAHLSLFWMILLALAAELFWFAQDLPWGMAAWGSGLMMAAGGLLIFLVHEAVHRQL
                     WPFRSWPALYASQAMIPVAAVLVVLLVLTNLQDGVVYRQTWLPLVNPLEEGAAFALLG
                     LIVFYRVSQRFFPVQISVCRPWPLIALLALSFWWLNGILLRALAWYGEVPWSAETLWH
                     SRLIQTCFALFWMLAALVVMLRATRRCSRREWLCGSVLLGIVIVKLMLVDSARGGGLA
                     RAVTFIGVAILVLIVGYFSPLPPKAGEEK"
     gene            10697..12092
                     /locus_tag="LSX49_002127"
                     /pseudo
     CDS             10697..12092
                     /locus_tag="LSX49_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383163.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3999 domain-containing protein"
     gene            complement(12279..12416)
                     /locus_tag="LSX49_002128"
     CDS             complement(12279..12416)
                     /locus_tag="LSX49_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168533.1"
                     /translation="MGQHGKSLPSFDAPETLKGRKIEWEYENLTHGNKAYNGYVTAIL
                     N"
     gene            12575..12772
                     /locus_tag="LSX49_002129"
     CDS             12575..12772
                     /locus_tag="LSX49_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168534.1"
                     /translation="MSNPGPLAALVYGFILIVLLSVSLILYSIGRTIKNEIGKGIAYA
                     LTGILLILSLLVGAFILTLLT"
     gene            12869..13225
                     /locus_tag="LSX49_002130"
                     /pseudo
     CDS             12869..13225
                     /locus_tag="LSX49_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(13848..14702)
                     /locus_tag="LSX49_002131"
     CDS             complement(13848..14702)
                     /locus_tag="LSX49_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011871062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL7168535.1"
                     /translation="MKYRFINDHREIWSIVTMCRVLKVARAGFYVWLHRPVSAGEKDN
                     QRLLELIRDAYALSGGVYGYRRVHGDLREIGEVCSRNRVARIMKRNRIQAVHGYKVPR
                     GVRGRPSLIAPNRVQREFTMVKPNQVWVTDITYIRTWQGWLYLAVVIDLFARNVVGWS
                     MKPTLSRELALDALLMAVWRRKPAENVIVHSDQGSQYGSDDWQRFCRANNLAPSMSRR
                     GNCWDNAVAESFFSSLKKERIRKRIYKTRDMARADIFDYIEVFYNRTRRHSHLGGVSP
                     EAFEKASP"
     gene            complement(14699..14983)
                     /locus_tag="LSX49_002132"
     CDS             complement(14699..14983)
                     /locus_tag="LSX49_002132"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL7168536.1"
                     /translation="MGTPRFTPEFKEEAVRQVTERGYSVADVSERLGVSAHSLYKWVR
                     SVRPDNSGHQAQDLLDARTEILRLKAQLKRTEEERDILKKAARYFAREPD"
     gene            complement(15094..16269)
                     /locus_tag="LSX49_002133"
     CDS             complement(15094..16269)
                     /locus_tag="LSX49_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HBL7168537.1"
                     /translation="MLTDTQCRTAKPKEKLYRLNDFNGLYLEVKPNGKKAWRYRFKLN
                     GKSSMFALGEYPTVKLAEAREKCEQARKQVADGVSPTQARQLDKIRKVNDASNTFELI
                     AKEWLQMKDWAGITKTRRLDMLERVVFPAIGKLPVREITPHHILKILQETAKRGAPTV
                     AAEARRTISSVFELAVATLRADSDPVWPVRKALPANKTQHKQALNPQQIGKLLSCFDN
                     SRGSYQVNYCMWLMWWTLARPAEATEAEWTEFNLDNALWTIPAARMKARREHVIPLPF
                     QAVKMLRTLQGLTGHRQHLFPGRDNPLGPMTSHSLRQLLKSLGWSGTYSPHATRTTGS
                     TRLNELGYRPDAIEAQLAHADTNNVRRTYNHATYLDERKVMMQEWADMLDKWVAGFK"
     gene            complement(16484..17575)
                     /gene="ychF"
                     /locus_tag="LSX49_002134"
     CDS             complement(16484..17575)
                     /gene="ychF"
                     /locus_tag="LSX49_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBL7168538.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAVRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            complement(17692..18276)
                     /gene="pth"
                     /locus_tag="LSX49_002135"
     CDS             complement(17692..18276)
                     /gene="pth"
                     /locus_tag="LSX49_002135"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL7168539.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGSGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            18554..18832
                     /gene="ychH"
                     /locus_tag="LSX49_002136"
     CDS             18554..18832
                     /gene="ychH"
                     /locus_tag="LSX49_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HBL7168540.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            complement(18887..20566)
                     /gene="dauA"
                     /locus_tag="LSX49_002137"
     CDS             complement(18887..20566)
                     /gene="dauA"
                     /locus_tag="LSX49_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HBL7168541.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNLEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(20691..21638)
                     /gene="prs"
                     /locus_tag="LSX49_002138"
     CDS             complement(20691..21638)
                     /gene="prs"
                     /locus_tag="LSX49_002138"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL7168542.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(21789..22640)
                     /gene="ispE"
                     /locus_tag="LSX49_002139"
     CDS             complement(21789..22640)
                     /gene="ispE"
                     /locus_tag="LSX49_002139"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBL7168543.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDIISIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLSTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLS
                     PLHRAML"
     gene            complement(22640..23263)
                     /gene="lolB"
                     /locus_tag="LSX49_002140"
     CDS             complement(22640..23263)
                     /gene="lolB"
                     /locus_tag="LSX49_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HBL7168544.1"
                     /translation="MTLPDFRFIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            23477..24733
                     /gene="hemA"
                     /locus_tag="LSX49_002141"
     CDS             23477..24733
                     /gene="hemA"
                     /locus_tag="LSX49_002141"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HBL7168545.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEERDDLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEIIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            24775..25857
                     /gene="prfA"
                     /locus_tag="LSX49_002142"
     CDS             24775..25857
                     /gene="prfA"
                     /locus_tag="LSX49_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBL7168546.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            25857..26690
                     /gene="prmC"
                     /locus_tag="LSX49_002143"
     CDS             25857..26690
                     /gene="prmC"
                     /locus_tag="LSX49_002143"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL7168547.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLEHVTGKGRTFILAFGE
                     TQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVALAQRNAQHLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            26687..27079
                     /locus_tag="LSX49_002144"
     CDS             26687..27079
                     /locus_tag="LSX49_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HBL7168548.1"
                     /translation="MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTLLLLSGIALMAKAHIQPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            27083..27892
                     /locus_tag="LSX49_002145"
     CDS             27083..27892
                     /locus_tag="LSX49_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HBL7168549.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH"
     gene            27928..28782
                     /gene="kdsA"
                     /locus_tag="LSX49_002146"
     CDS             27928..28782
                     /gene="kdsA"
                     /locus_tag="LSX49_002146"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HBL7168550.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
     gene            complement(28931..29038)
                     /locus_tag="LSX49_002147"
     CDS             complement(28931..29038)
                     /locus_tag="LSX49_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HBL7168551.1"
                     /translation="MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK"
     gene            complement(29443..30543)
                     /gene="chaA"
                     /locus_tag="LSX49_002148"
     CDS             complement(29443..30543)
                     /gene="chaA"
                     /locus_tag="LSX49_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HBL7168552.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSLWHAIWLIVHLIAVIAVTKMNASPLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
     gene            30813..31052
                     /gene="chaB"
                     /locus_tag="LSX49_002149"
     CDS             30813..31052
                     /gene="chaB"
                     /locus_tag="LSX49_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HBL7168553.1"
                     /translation="MSYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKEDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKSSNR"
     gene            31201..31896
                     /gene="chaC"
                     /locus_tag="LSX49_002150"
     CDS             31201..31896
                     /gene="chaC"
                     /locus_tag="LSX49_002150"
                     /EC_number="4.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-specific
                     gamma-glutamylcyclotransferase"
                     /protein_id="HBL7168554.1"
                     /translation="MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGRTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENYPDGVLRPGFA"
     gene            complement(31940..32293)
                     /gene="ychN"
                     /locus_tag="LSX49_002151"
     CDS             complement(31940..32293)
                     /gene="ychN"
                     /locus_tag="LSX49_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HBL7168555.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQENNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            32478..33872
                     /gene="ychO"
                     /locus_tag="LSX49_002152"
     CDS             32478..33872
                     /gene="ychO"
                     /locus_tag="LSX49_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HBL7168556.1"
                     /translation="MSRFVPRIIPFYLLLLAAGGTANAQSTFEQKAANHFENSNDGLP
                     DLGMAPEHHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDDGLVSNV
                     GVGQRWARGSWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVVESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSEEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            complement(33873..34523)
                     /gene="narL"
                     /locus_tag="LSX49_002153"
     CDS             complement(33873..34523)
                     /gene="narL"
                     /locus_tag="LSX49_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HBL7168557.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(34516..36312)
                     /gene="narX"
                     /locus_tag="LSX49_002154"
     CDS             complement(34516..36312)
                     /gene="narX"
                     /locus_tag="LSX49_002154"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HBL7168558.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALIRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQSDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADTHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWVQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            36651..38042
                     /gene="narK"
                     /locus_tag="LSX49_002155"
     CDS             36651..38042
                     /gene="narK"
                     /locus_tag="LSX49_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HBL7168559.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWI
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
BASE COUNT         9212 a         9358 c        10056 g         9617 t
ORIGIN      
        1 tatttcattg ctgaaccaca tattagtttc tctttgttac tatttgcata aaaagtatat
       61 ttttgatata ataatattgc tggtgaacta tattttaccc agtcagtacg ttgtcatgca
      121 cttaccattt attaggtgat taaaccccac ctgtgctggt gcagacataa cgtcttatca
      181 gaatatattg aacaggaaaa tcactgatga atattgtcca tcaggaaggg ctagctatgc
      241 ccgtcgatca ggaattaata aatatcatat taaatgaagc gggaaatcca ccgccgcata
      301 aagccaaaat tacagccgtc agtctgttat ttaaagacct gagttacagc gctgaaaagg
      361 gtggttacca tcctgtcgaa atacggatta tttcacgcaa tgatgaatgg tattttgatt
      421 acattaccga cttcagttat atggggacgg tataccccga acttgaaaag gaaattgata
      481 tcagctggag tcagcaatat gtctttcttg cttatgttgg tgacctgcct gttaacgccg
      541 gaagggagct gtttgaactc tggcaatcca actttattca gtatcacggc atgaacatct
      601 acaccattac cgttctctgg gaaagctaat ccccctgtac taaccatcac taatttatgg
      661 ggaattatct gtgacgactg acagagggat acgtgcgtct caacagggcg aactggactg
      721 tctttgcggt gcttattgcg tggttaacat gctgagctgg ctgtatgacg gcagggtgaa
      781 acgacgcccg ttaatgaact ggcttattca gacttatcag cagcgctggc ctttgcatga
      841 atggctgact gaaggaattg aagaagaccg cttagactgg ttaatagctc aggtgttgca
      901 gaaagggcat taccgccgcc agttcccggt tgaaatcacc agaccctttg cagggaagcg
      961 ggggttaaca gacgggcggc tgttcaggga aatgcagcgg tttcttgacg tcactgacca
     1021 ctctcgcctg attatgctca gcgaccagtt tcactggtcc cttctggtca aaatggacga
     1081 agaaatgctc tgcttcttcg acagcaacgg gcgaaccacc atgccccgta aagctttctc
     1141 cctgcgtact ggcgtaaccc gccgccagct gtttccagac gccatttact tcattgaacg
     1201 ggagttctga catgaccatg tttacccagc gtgaaacccg tatccttgac caggcgcgtg
     1261 acattattag ccggtactac cagcgtgggg ttcaactctg ttcccctgat gatgttcgac
     1321 ggtgcgtgat ggttgagctg gcaccgcttg aacatgaaga gtttggcatc atcctactcg
     1381 ataatcataa tcagctgctg caccgcgaaa tcctgttcag gggtacgcta aactcggtca
     1441 gcgttcaccc ccgtgaagtt attaagcgtg tgctgaaaca taacgccgcc gccgtcatcc
     1501 ttgtccataa tcaccccagc ggcgagcctg aacccagccg gtgtgacatc cagttgacca
     1561 aaaagcttca ggagctgctg gaaatactgg atgtgcggtt acttgatcac tttatcgtgg
     1621 caggaactga aacggtgtcg atggctgagc gaggactggt gtgatgctga aagttacttg
     1681 gtttaatgta cgttattgcg ggttacgcgc atgagcagga cagcgttgcg tcaggtcgtg
     1741 ccggtggtgc aaaccaccgt gttcgatgcg tatattgtcg gtctggcccc ctcgggacgg
     1801 cgaggtatca ccagcctgtt aaaccgcagc gccagcatac ttaaacacgg tgcggatgca
     1861 gcagactatc cgtgggaaca acttaactac gccgccgttg ccaaagtgcg cgcggcactg
     1921 ctggatgacg gttacgccgt gtcatcggtc aacatggcgc tgtcagcact ccggggcgta
     1981 gcgcagacgg cctttaacct caattacatg gatgccgaaa cgctggcacg tatccggtca
     2041 gttaagcgcg tgagcggcga tgtccagcgc aagggaaggg cgctgggcag gcaggaaatc
     2101 cgggtactga ttcaggctgc aaaacagcat ccgcaatctg tacggcgctg tcgcgatgtc
     2161 gccattgtgc tgatgctttg cggaacgggc ctgcgggccg gggaactggt taaacttgag
     2221 cgccgggact atgacaacgg catcctgacg gtgaggcaag ggaaggggcg taaataccgt
     2281 gaaattcacg tggcggatgc ggtggacaag gctattcgtg cgtggctgaa agttggcgca
     2341 gacgaggctg acagtgcgtt gtttaggcga attcagcgca gtggtaaggt cgcaagccaa
     2401 ccgctgacta cgaccgggtt aacgggtatc ctggctgagt tacagcaaac ggcaggtata
     2461 gcacgtttta ccccgcatga tatgcggcgc accttcatca cccgtttgct ggagcagggc
     2521 gtggatatca ataccgtccg ccagttggca ggccacagcg acatatccac gacgacgcgc
     2581 tatgactgtc gtggtgatac tatgaagatc agtgccagca agcgcatcag atgtttttag
     2641 cagttgaggc gttgccagac tcggtttcag tttcatcttc agcactcaac cgcgcgtact
     2701 tttgattctg gatgttaatt tgtgcattga tattttcagg ctgaagcatc cacgcaacat
     2761 cctcacgcgc ccattcttta ccgtcagaga gtcgttttaa ccggggtttc catattccat
     2821 actcattaag tttttctgct accgaagcat atttctcacg atctgactcc cccgtatgaa
     2881 gcttgtcaaa acgacctttt acaagctggt aaacagtata gatttccagt gccttagggg
     2941 acctggccgg gactatcatg gggtgttcct ccggcctata aatcccgttt ggctctccct
     3001 cattgagcag gtcattaaac atgtggttca cgcaggcact cagcacatct gccgctttct
     3061 ccgcagcgaa tttatccggg ctaaaacccg ctcccgtcag tttccgggca atcagtgcca
     3121 gtttttgccg ggtatcccgt cccagataaa gcttcttctc cagaaattca aagacctcgt
     3181 tactgctttt ccgttcccgg tggcatctgg cgtcagcctt gttgctttgg ttaccaatca
     3241 tagtcacctc catgacagtg ttttgtacaa aatatcacca ttgagcctca gtgaaaattg
     3301 cttctttata tgaccgttct ggagacagaa atagatgatc tcgaatgaca tccacattaa
     3361 agatgccctt aacgtgctca acgaaggcat cgttgagtga atccttgcgt tttttggtgg
     3421 ttgtaaataa cccgctcctg aaacagctca aaggagcaca agcatgaaca ccaaccgtat
     3481 tttgcgtaaa aaagaggtac ttcatctgac ggggaactcg tcagcgacgt tgtaccgact
     3541 catctcgaaa ggattctttc ctttgtcaaa gaggctaacg ggcgacaatg gccgggcggt
     3601 aggctggctg gagagtgata tcaataactg ggttaacagc cgtatgcagg cgggagaatg
     3661 aaatgaaaga gataaaatcg aaaaccagtt ctgcgaaaaa aacgctggtt ccttggttcg
     3721 aaactatggg gaaacaggtt ggtttatcac aagaaacgat atcagcagtg ttaaaggagc
     3781 agcgtttacg gatacgtaag cttaactacg catctgcata tacagtgtcc aatattctca
     3841 tacaggattg cggcggggcc gatgacatgt ggagcaacta cgctaaactg gcgcttatcc
     3901 ttgagcgttg taaatacatt ccctgcggga gcagggcctg tgcatattgt tctaccgctc
     3961 agcaattaca ttatcagggg gtggatgtaa ccggggaata cgctttatat cagttgcctg
     4021 agttattttt agatttttta gaaacaaacg acaaaaattc ctcttatcat tgggattaca
     4081 ataagttagt tgagcggcat gaagatgctc aggcgaggtc attcgggtaa tagccatttc
     4141 tgtatggtga aaaactgaca tattaccctg ccactgcatt ttggtggcag ggtaatcaat
     4201 acagctagga atattaaatg aacgattctt attacttcag aacatctgac ccggattaca
     4261 ttcgtcacgc accgtcaatg cttgagattt taagtaaagc attccccact attattaccc
     4321 agcaggaaag tgagtatgaa ctgcagcgtc ttaaccattt actaaataaa ctgaaaggca
     4381 gcaatcgctg ctacaacatc attgctcaaa aactaaggca gtgcagaaac ggatctccat
     4441 gcaacagtct tatatgcccg cattgccagc gggaacgcat tctggcgcaa ctggctatgt
     4501 tgcatgtctt gccggggaat tcagcagaat acgtgggagt ggtcctgttt ttcaacaagg
     4561 atacgcaaac tccgccgcca tggaagaaca ttggggcgct cagggcgcaa atcggtcgtt
     4621 ataagcagag gataagccgg gtacttaacc gcctggggta cgccggtccg gccacaggca
     4681 ccttcagtat gatgcgacat atgcctgatg gcccagaaga gcgtattttc tgggttccac
     4741 agttgtgttt gttcctgccc aatgacagta cgttgattaa ggggctaaaa gcgcatatgt
     4801 cgcgaagtgg tggggcattc attgatgcat cgacgcttaa cacaccagtg atcgtgctca
     4861 ggtataaaga tcccgcgaga ctgatttcat gcgccctgaa tccagtctgg cacacagcag
     4921 attacacact gactgataaa gacgctcttg ttaagtcaag aatggagcta ctgaaaggcc
     4981 ggacactgtt aaaaagtctg cttaccctgg actcactcgg aacaggtgtc gtttcttttt
     5041 cgtttgggca acccccaggg aaagtgcact gatttaccgg taatgcagca actgcaatgc
     5101 acttttgctg ttgattaaat tgcagtggaa cgacgaataa cagcggcaac cactgcattt
     5161 tcgttgttgt aaaactgcaa agcttgccag tgattttgat ggcgctgatg cactttaaca
     5221 ttccaactgt ctcgatttta acgcaaccgt ctgttttctg caggggctca cggatgcctc
     5281 tgcacacccg atccttacca tcaactgacg agttagcgca tctgtgaggg ctttctgtgt
     5341 ttctgtcagt gaatattcta cacacaatgg ggggagcggt cagcgagcac cattgccatt
     5401 gagcgcaacg gagagcttgg ggacatgcag cactacggag gcttcatctc cttctcatgt
     5461 cattaaacga tacggcgaac gagcgcagcg agtgagggaa ggcgtcagcc tgaacagggg
     5521 gaaagatttg cgaccggagt ggagcaaatc atgggcggag cccatcctcg cgactggggt
     5581 tttgactttc gaattgccca gcgttgagtt tggttaatgt agtgagacga ggatgctgag
     5641 aggggaccgt gagtactgaa aaggattatc cagtgaagat ccctaagtgg gtttatgacc
     5701 gtattactga aataacggat tatgtcgtgg gggatacgca atgggctgtt acccggcggc
     5761 agacagtacg gtggttcctg gctcacatat ggctggaaac agacgatgat ggctggacta
     5821 tatgcactgt ccgggatatc cgtagcagct atgccagtct cctgggacag tgtgaaatta
     5881 gttaccaggg ggagtgcttt atgtccacgc taactgattt cctgccgaca ctttcggata
     5941 ttgaatttcg tgcaggaaaa gcgagcaaag acccggaaaa gcgtagagcc agtgcatggc
     6001 ggttcaaccc cctgctgcct gtgtgtgatg agtctgccag gggtaagtta aatctggttg
     6061 acttggatac tggtgagtct gttagtttta gagctctgct tcaggggaac gggaaagctc
     6121 ctgggcatgc gatagatgta gagaaacgcc agacggccct aaaacaaacg gaaaaggact
     6181 tcttggccaa agttgggcgg gggcgcatga gtatacagtt tgtgaaggaa ttgcgtagcc
     6241 gtgagccgga tcactattac cgcgcaggaa tacgcagcct taaccatctc tacaatggca
     6301 ggattgaggg acaatatgtc acttacgacc atcattatcg tctgacgttt ggagggcggt
     6361 attatgatca agctttccag aatctgccca atgagttcaa agctaaattt cggaccgggt
     6421 tactcaacta tgacatcgaa gcgtgcaatc tggcctgtct gaaccatctg ttcagacagt
     6481 atgacgtcga ttatcgtgtg aagtcatcga tatataaaac catgatggaa cataccgggc
     6541 tgacccgtaa acagtgcaaa cagatggtcc ataccaccac ctacagaatt gggcgtgtga
     6601 ctattggtgt taatgatggc cttggggcaa aagtgtatgg atggtgcggt aacagcaaaa
     6661 aaaaggcgct aaagattttg cgttggtgga accgttatat cagtccattg aaatctgcgc
     6721 ttgagtcatt gctggaacgt gtgcatggcg cacaccgcaa gagttgttca tcaccgcgta
     6781 actatcacag gtacgctaat gaagtcggat taatactgga tcttaatagt gaggtgtatc
     6841 agcgtgaaaa gactcaccat catcaatatg cgcggaataa ggcactgttg gcgtttatga
     6901 tctgtggtgt ggagcaggcg tatatccgtg aggttgtcag tatgaaccct ggtcgtgtct
     6961 gcatgctgga tcatgatggg gtagtggcaa cgggcgcgct ttcactaccg gactggcgtg
     7021 gtttcacgat gaaagtgaag gactagctta ctttcttgaa tttaactatc tgcgatctct
     7081 gataagggcg tattacgttg tcaatcataa tgggatatgc gcattggaac gatgtgcata
     7141 tccagtaagt gatccatgtc cgctttgagc tgtgagttca acgggtcgat gcaacgctgt
     7201 ccctaatcaa gggggacgtt gccatgaaac gaagaactcg tattaactac acgccagagc
     7261 aaaaggtgat tatttgggac agatataagc aaggtgattc cctgcatgat atcccccaga
     7321 atgttcgaca gatttcactc tactatcatg cctacaatcc accaggccgg tggctaccgt
     7381 cctcccgtgc gaaagcggca ccggttagcg ttttcgcttg atgaaaaaga ggagatatcc
     7441 agaggactgg tagcaaaacg catcatcagg gacatcgctg ctaaattatc aatagctccc
     7501 tcaacgatta gccgcgagat caggaggcac ggcggtgcaa aacaataccg tgcagcaaaa
     7561 gccgatcctg ctgcgtggga aaatgctctg agaccaaaac cttgcaagct aattgaaagc
     7621 cccacattgt gtaaaatcat tgcagagaag atgcatcagg actggtcgcc ggaacaaatt
     7681 ggcggttggc taaaacgctg ttatcccgat aatcaggaaa tgcatgtgtc acatgaaatg
     7741 atttataaaa cgctttttat accaacccgg ggagctttaa aaaaagagct gcagcaatgc
     7801 ctcagaagcg gaagagtagt gcgtagatcc aaaacctcat cacttaaagt aaacagagat
     7861 acattctggt cacgaatgcc cggttgttcg tgctttgcgt tttaatcgca ttttacagtt
     7921 tctgcctgcg tgcagaggtt gatggtattt tctgaaaaag cggctcgctt tgctaatgca
     7981 tatggcacaa atacaacagt ttgtgtcatt ctgacccatc tttataccgc gacggtggaa
     8041 acatggatga gctgctaacc cttggctgca ttgctttatt cttcgcactg gtggtggttc
     8101 ccatcctcgc gattatcgcg ctcagccgca gcacggctgt tcgttctgag ctggcgaccc
     8161 tgcgtcgccg ggtggaggtg cttgagcagc gcggtgtgac tgaagcaccc gccacagtgg
     8221 taacaactgt gccgcagagt gtttcgcaga tggttgtgcc tgttgaaacg tcttcgcctg
     8281 cggttaacat cgtgctgtcg gagcctgtgg ctgatgtcac gcctgagtcc gttgacccct
     8341 ggcgtccaca accgaagccg caaaacgagg cgctacccac accagcggtc gaacaatctt
     8401 ccgcttttgg tggggtgatg tcgtccctgg tgcgctggtt tatgcagggc aacccgctgg
     8461 caaagctggg tattctgctt ctcttccttg gcttctcctt cctgctgcgt tatacggttg
     8521 aacactccct gttcccgctt gagctacgtc tggtggcgac ttcgctgttt gcgattgccc
     8581 tgctggtagt gggctggcga ttgcggcata aacagctggt ttatgcgctg atcatacagg
     8641 gtggagctac ggggacgctc tatctcaccg tttttggcgc attctggctc tggcagatgc
     8701 tgccgatgac gctggcgttt gcattactgg tggcgatttg cgcggcgagc gtgggactgg
     8761 cgattatgca aaaagcgctc agcctcgcga tgctggcaag tatcggtggc tatctggcac
     8821 cgctgttgct ttccaccggc ggcggtagtc atgtggcgct cttctctttc taccttctgc
     8881 tttccgtcgg tattctcgcc atcagcatct ggcaacactg gcgcgagctt aatctgcttg
     8941 gcctgttatt tacctttggt atcggcggtc tttggggact cgacggctat cgatcagagt
     9001 attacctgag cagtcagctt ttcctgatag ccaatacgat catttttggt gtgctgagcg
     9061 tggcgctatc gctacgagca caggagaaag gtaagcagat tattgatggc gtgctgttgt
     9121 ttgcatcgcc gctggtcggt tttggcatgc agtacgccat aacccggcat atggaatatg
     9181 gtccggcgct tagcgcgctg ggttacggcg gtttctatct ggcgttagca tggcttgcat
     9241 tgcgtcgcta tccctctttg gggaggccgc tggtgctggc ggcgctggcg ctgggtgggg
     9301 catttaccac gctcgctatc ccactggcgc tttcggcccg ctggacggcg atggcctggg
     9361 cgctggaagg tctcggcatc ctctggctgg gcgtgcaaca gcagcagcgg cgtatgagct
     9421 atagcggcac tgcgctgctg gtgctggcag tgtgcagcgc gctgtgggcg cagatgaacg
     9481 ggatgagcgc gctttctctg gtgctaatct ttgccgtact cagcctcagc tggctggctg
     9541 ccgcctggct gtggcgcaat attcagttgc agggtagttg ggttctgttg gctggcggtt
     9601 tgatcttctg gataatcgcg ctcattgggg catcgcaact ggtgctgaaa aaggactcgc
     9661 tggtgctgtc tggcgtgctg gcgttaatgg cgatatcggt ctggggctgg cggattgtct
     9721 ctggtcgtct ggcctggtgg gagctggatg tcagcaaatg gttgctgtgg ccgacgatgc
     9781 tggtgatgct gctgtctcaa atttcacaac atgagatttt tgctgcgggc tggcagaatc
     9841 tggcctggtg tctggcgtta cccgctgcgg gggcattgct ctggcgtgat gctgagacgt
     9901 tgccgccgcg cctctccaga ctggcgcacc tttcactctt ctggatgatt ctgctcgcgc
     9961 tggcggcgga gctattctgg tttgcgcaag atctgccatg gggcatggcg gcgtggggct
    10021 ccggcctgat gatggccgcg gggggcctgc tcatctttct cgttcatgag gcggttcatc
    10081 gtcagctatg gccattccga agctggcccg cactctacgc ttctcaggcg atgataccgg
    10141 tagctgcggt attggttgtt ctgctagtac tgacgaattt gcaggatggc gtagtttatc
    10201 gccagacctg gctgccgctg gtgaatccac tggaggaggg ggccgctttt gcgctactgg
    10261 gactcattgt attttatcgc gtttcgcagc gctttttccc ggtgcagatt tcggtatgcc
    10321 gtccctggcc gctcattgca ctgctggcgc ttagcttctg gtggctgaat ggcatcctgc
    10381 tgcgcgcatt ggcctggtac ggcgaagtgc cctggagcgc ggaaacactg tggcattcgc
    10441 ggctgattca gacctgtttt gccctgttct ggatgctggc ggcattagtg gtgatgctac
    10501 gtgcgacccg gcgttgctca cgtcgcgaat ggctttgtgg atccgtattg ttagggattg
    10561 ttattgtgaa actgatgttg gtagacagtg cgcgtggcgg cggcctggca cgcgcggtca
    10621 cgtttatcgg cgtggcaatt ctggtgctaa tcgtcgggta tttttcaccg ttaccgccca
    10681 aagcgggaga agaaaaatga aatggatgaa agcggtgtta tgcagcgtgc tactgagtac
    10741 tgcgggcgcg gcggtcagca gcgatgaagt gaaggaagcg ccaacggact acgcaacagg
    10801 cgtcgcgctg gaaaccacgg gggcattcgc cctggtatcg catttcgctg ccgcaggtgg
    10861 tgtatcagag cactgcatgg ccggatttgc gcgatgtgcg ggtttttaac catctggggg
    10921 atatggtgcc gtttgcgctg gtggcgcaga aaacccagac cgttacgcca gagacagtgg
    10981 ctctgcgtct tttcccgctt gatatgtcgc cggttccgcc gcgtgatgag ggtcaacgta
    11041 gtggggatgc tgttgtttta cgttcaaaaa acggtattga aattcatttg caaagcgatg
    11101 atgtcactgc gctcgggcag agctatttac tgacgttgcc ggaagagagg aaagactctc
    11161 tttcactgac gcaattgcgt ctgaactggg ggacgccgac gggcaactgg caggggaaag
    11221 cctcggttta tgtcagccgt gatttacgct actggcgacc cgtgcaggaa gatgcgccgt
    11281 taatggatct gacgcgggat agcgatcgtc tgaaaatgga cgccatcagc accaacctga
    11341 cattgtcact tgaaggaaat cgctacctgc tggtgatcct caactcgcaa agcccggcac
    11401 tgacgttaaa cagcgtgagc gctattgctg acagtaatga gccggagtcc gaacgtattg
    11461 tgattggcgc tcgggcggat aaggtgtcgg atgatgaagc cgtctggcga tggacacagc
    11521 cgcagcccct gacatcgttg cggatcgatc tggaaaatga aggcgtttta ccggtggaac
    11581 tggtctggcg cagcggcgaa aaagaaccct ggcagtcact gacaaaaacg gtgttgtatc
    11641 gcctggacgg gaagcgttca gaagatattc gtcttcctgg ccagttagtt gaggctgttc
    11701 gaatacgtac aattaatgcg cgattgccgg aggcattgcc agcattgagc ggtgcgcgcg
    11761 acagttatca actggttttt aacacgcaag gcaaaggtcc ttacatgctg gcgtggggaa
    11821 accgggcggc gaaaaaggcc gatgttggac tcgatatgtt gatccctgcg tcgctgcgta
    11881 aaacgcagga gatagataat ctgccgtggg ctataccgca ggagagcgta actctcggcg
    11941 gtgaattgcg actaacggcg acgtcggcag ccgaacaaca aagtcagtgg aaaacgctgc
    12001 tggtgtgggg ggcgttaata cttggcgttg ccgttctggc gtttatggca tggcgaatct
    12061 ggcgagaagt taaaaaggac ggtgcggcgt aagccataaa aaagcacagt tgcatagttc
    12121 acggtgttga taaactgtta caacagaggc gtttaagctg aggcggggaa ataatctatt
    12181 tgtgaataat atgttacttc actggggcgt gagtcatggg aatgattttg atacctgcgt
    12241 tttttatttt agccatcctg attatcgcta tcttcatttc agttaagaat ggccgtcacg
    12301 tatccgttgt atgccttgtt gccgtgggtg agattttcgt attcccattc tattttacgg
    12361 cccttaagcg tttccggagc atcaaaactt ggtaaagatt taccatgttg acccattatg
    12421 cggcccctct ggagaccact ttcaggtatt ttctctactg atatgtacac atggagagat
    12481 gtgattgcaa attcccatca gcattactac caaaagaatc agacaggaag cagcatagta
    12541 ttaataagaa tattttcaaa cataaaggat gattatgagt aacccaggcc cacttgcagc
    12601 gttagtgtat ggttttattt tgatagtttt gctatcggta tctttaatcc tttattcaat
    12661 tggacgtacc ataaaaaacg agattggaaa aggtatagca tacgcgctta ctggtatttt
    12721 attaattctg tcattattag ttggcgcttt cattttgacg cttcttacat aaattcctcg
    12781 aaaaatacgc tgacagcatc agctaatgga cccgactctc cgttgaacgc atgctcgcct
    12841 gcggcacctg tgccatgggc gtccgccgct acgggcaggc atcaaggttc gcttcacaac
    12901 agcggacctg ctgctacagc tatccacttc atagcgccag ggccgttaca aaacgacact
    12961 caatcgcggt gtcatggccc cgaagctact tatcatcgat gaaataggtt atctgccgtt
    13021 cagtctggaa gaagccaagc tgttcttcca ggtcatcgct aaacgttacg agaggagcgc
    13081 gatgatcctg gactccaacc tgccgttcgg gcagtgggat cagacgttcg ccagggatgc
    13141 agccctgaca tcggcgatgc tggaccgtat cttacatcac tcacacgtag tccagataaa
    13201 aggagagagc tatcgactga agtagaaacg aaaggccggg gttatacctg aagctaatcc
    13261 tgagtaaaca aggtggatca atattaaacc gttggtggtg acggttagtg gatcacttta
    13321 ttacccgttg ttgacagtaa acgcaggaag tcagatgtga tgcgccgaaa gctgctttcg
    13381 cacatgttac agggactgga aagccgggct gtttacgatt acgttgccag tcataagggc
    13441 gtttgcgcac tggagcacga tgggtttttt tcatataaag aggtcactga ctggtcccat
    13501 ccatatctgt tgattgagaa aaagcattaa ggggagccac tcagtcaatt acagcttatc
    13561 tcggttgata aacaagacgg gacatttagc actttcatga tatgcatagc cggcaggtga
    13621 tcttagcctg ctttcagcga tgaaccacac aatattcccc ttttgttact ttgatatgat
    13681 tgctcaaaat gggtggtaac actgagatcg ttgaaatgac tgcatgttat attgttactt
    13741 ttgttaccgt tgaaaacatc acgttggaga gctaaatgga ttggccaaag gagtacagca
    13801 agacgactca agtggagtga ccacattccg gtagacagtt tctgtcctca cggtgaggcc
    13861 ttttcgaagg cctccgggct gacgccaccc agatgactgt ggcgccgggt ccggttgtag
    13921 aacacttcaa tgtaatcgaa gatatccgcc cgggccatgt cccgggtttt atatatccgc
    13981 tttctgatgc gctctttttt cagtgaactg aagaacgatt ctgccaccgc attatcccag
    14041 cagttgccac gacggctcat actcggcgcc agattgttgg ccctgcagaa ccgctgccag
    14101 tcatcactgc catactgact gccctgatcg ctgtgcacta tgacgttttc tgcaggctta
    14161 cgccgccaga ctgccatcag cagcgcatcc agtgccagct cgcgcgacag cgttggtttc
    14221 atcgaccagc ccaccacatt acgggcaaaa agatcgataa ccaccgccag atacagccaa
    14281 ccctgccagg tgcggatgta ggtaatatca gtcacccaca cctggttggg ttttaccatc
    14341 gtaaattccc tctgtacgcg attaggagct atcagtgacg gccttcccct gacgccacgc
    14401 gggaccttat agccatgtac ggcctgtatc ctgttccgct tcatgattct ggcaacacgg
    14461 tttctgctgc atacttcacc gatttcacga agatcgccgt gaaccctgcg ataaccgtag
    14521 actccgccgc tcagtgcata agcatcgcgg atgagctcca gcaaccgctg attatccttt
    14581 tctccggcag aaacagggcg atgaagccag acgtaaaatc ccgcacgggc gaccttcaga
    14641 acccgacaca ttgttacgat cgaccagatt tcacggtgat cgttgatgaa gcggtacttc
    14701 agtcgggctc ccttgcaaag taccgcgctg cctttttcag aatatcccgt tcttcctcag
    14761 tacgtttaag ctgcgcttta agcctgagaa tctccgtccg cgcatccagt aaatcctgcg
    14821 cctgatgccc gctgttatcc ggtctgactg accggaccca cttataaagg ctgtgagccg
    14881 atacgccgag gcgttcagaa acatcggcaa cggaatagcc ccgttcagtg acctgacgga
    14941 cagcttcttc cttaaactct ggggtaaatc gtggtgtgcc catagactcc tcctatgctc
    15001 aaactatagg gcagatttgt ctacgggctt gggggcactc cagaaccttg aggaataagt
    15061 tctatcctcg tggttcactt tgtgcagcaa gttctacttg aatcctgcta cccatttgtc
    15121 caacatatca gcccattcct gcatcatcac tttacgctca tcaagataag ttgcatggtt
    15181 gtatgtgcga cgaacattgt tggtatcagc gtgcgcaagt tgggcctcaa tagcatcagg
    15241 tcgatagccc aactcgttta aacgggtact tcctgtggtc cgggttgcat gtgggctata
    15301 tgtaccactc cagccgaggc ttttaagtag ctggcgcagt gagtgcgatg tcattggacc
    15361 tagcggattg tctctgcccg ggaaaaggtg ctgccgatgc ccggttaatc cctgtagtgt
    15421 tctgagcatt ttgacagctt ggaagggtag gggaataacg tgttctctgc gggctttcat
    15481 tcgcgctgcc ggaatagtcc atagggcgtt atcaagattg aattctgtcc attctgcttc
    15541 ggtggcttct gcaggacgcg ccaatgtcca ccacataagc cacatgcaat agttaacctg
    15601 atacgagcca cgactattgt caaaacagct tagtaacttt ccgatttgtt ggggatttag
    15661 tgcctgtttg tgctgtgtct tattagccgg aagggccttg cgcacaggcc atacgggatc
    15721 gctatcagct ctaagcgtcg cgactgccaa ctcaaaaact gatgaaatgg tgcgacgggc
    15781 ttcagcggca actgttggtg ctcctcgttt agcggtttcc tgaagaattt taagtatatg
    15841 gtgtggagtg atctctctga cagggagctt accgatggcg ggaaaaacca cacgttcaag
    15901 catatccagt cgccgcgttt tggtaattcc ggcccagtct ttcatctgca accattcttt
    15961 agcgattagc tcaaaggtgt tggatgcgtc gttgaccttg cggatcttat ctaactgacg
    16021 agcctgtgtt gggctaactc catctgcgac ttgcttacgc gcttgctcgc atttctcgcg
    16081 agcttcggca agttttaccg tcgggtactc acccagcgca aacatgctgg atttaccgtt
    16141 gagtttaaac cgatagcgcc atgccttttt accattgggt ttcacttcga ggtagagacc
    16201 attgaaatca ttaagtcgat agagtttttc tttcggctta gcagtgcggc attgcgtatc
    16261 agtgagcata acggggcctt gtttatttat tataccgtta ttgtactcac ttaaaatgaa
    16321 gatggaagaa tgttgtactc atccatgtac tcatttttga cagcgttgtt atgagatgaa
    16381 ttgagacatt gcgaaatgaa aaatccacgc aattgcgtgg attttataga gttttacggt
    16441 tcttatgaga ttcagtgaaa cctcatgaga cagcagattt aatttagacg ttgaacagga
    16501 agttcatcac atcgccatct ttaacgatgt aatctttgcc ttctgcacgc attttgcctg
    16561 cttctttcgc gccttgttca cctttgtaag tgatgaaatc ttcaaacgag atggtttgtg
    16621 cacggataaa gcctttttca aaatcagtat ggattttgcc cgctgcctgc ggcgcggttg
    16681 caccaaccgg aatggtccat gcacgcactt ctttcacccc agcggtgaag taagtttgca
    16741 ggttcagcag cttataaccg gcacggatca cacggttcag gcccggctct tccagcccaa
    16801 gctcctgcat aaactcgtca cgctcttcgt cgtccagttc ggcaatgtct gcttcaacag
    16861 cagcacaaac cggaactaca acagaacctt ctttcgctgc gatttcacgc acctggtcaa
    16921 gatacgggtt gttttcaaaa ccgtcttcgt tgacgttggc gatgtacatt gttggtttta
    16981 gcgtcaggaa gctcaggtaa cgaacagccg ctttctcttc agcgcttaaa tccagcgcgc
    17041 gcagcatacc tgcgttttcc agctggggca ggcatttttc cagtaccgcc agctcggctt
    17101 tcgcgtcttt atcgccacct ttggctttct tctgtacgcg atgaatcgca cgttcacagg
    17161 tgtcgagatc cgccagcgcc agttcggtgt tgataacttc aatatcatcc gccgggttaa
    17221 ctttgccgga aacgtgaatg atgttgtcat tttcaaagca gcgaacaacg tgaccgatcg
    17281 cttcggtttc acggatgttg gtcaggaact ggttacccag accttcgcct ttcgatgcgc
    17341 cttttaccag accggcgata tcgacaaatt ccatggtcgt gggaagtgta cgctgcggtt
    17401 ttacgatttc agccagttga tccaggcgag ggtcaggcat tggtacgacg ccagtgttcg
    17461 gctcaatggt gcagaatgga aagttggccg cttcaatacc ggctttggtc agcgcgttga
    17521 acagggtaga tttcccgacg ttgggcaaac cgacgatacc gcatttgaat cccatgattt
    17581 aaatcacctt aatatcttaa taatcaacct gttattgcta acagattgca gaaatggaaa
    17641 taactttgcc tattatacac ggcactcggc aaaaatgccg cagacaacga cttattgcgc
    17701 tttaaaggcg tgcaatcggt tcgttgcttt ggtcaagcca tctgtaaacc acatttcagt
    17761 acaacgcgcc gcttcgtcga tggcttcatc aattaacttc tgttcactaa caggcggttt
    17821 gcctaacaca aaaccgacaa ctttattttt atcgcccgga tgaccgattc cgatgcgtaa
    17881 acggtgaaag ttagggttat tacccaattt actgatgatg tctttcagtc cattgtgacc
    17941 accatgaccg ctacccaact taaatttggc gacgccagga ggcagatcca gttcgtcgtg
    18001 ggccaccaga atttcgtccg gattaatgcg gaaaaaactg gccatcgccg caacggcttt
    18061 gccgctgaga ttcataaatg tagtcgggac taacaggcgg acatcttcgc ctccaagggt
    18121 gactcgcgaa gtataaccaa agaatttagc ctcttcgcgc agcggagcgc gcaatcgctc
    18181 tgccagtaag tcaacgaacc aggcaccagc attatgtcgc gttgcggcgt attcagcacc
    18241 ggggttcgcc aggccgacaa tcaatttaat cgtcacgttt ttttgtcctg agtgtgtaca
    18301 taactggcgc gtagtttact ggttgcggcc ccgcttgaca aaaaactgcg tatcaaatgc
    18361 agataatgca attattgcct aagtggacta ttagaaagtc aaggtgttca ggcgtttatt
    18421 tgtaaagttt tgttgaaata agggttgtaa ttgtgatcac acccgcacat aacccacagg
    18481 gtgttgtcta tactttacac ataaggaaga ggggtattcc ctgttacaac ccagaaagtt
    18541 ccggaggtga catatgaaac gcaaaaacgc ttcgttactc ggtaacgtgc tcatggggtt
    18601 gggtctggtg gtaatggtgg tcggcgtggg gtattcaatc ctcaaccagt taccacagtt
    18661 taatatgccc cagtatttcg cacatggtgc tgtgctaagt attttcgtcg gtgcgattct
    18721 ctggctggcg ggtgcccgtg ttggcgggca tgaacaggtg tgcgaccgtt actggtgggt
    18781 tcgccactat gacaaacgtt gccgccgtag cgataatcgc cgtcatagct aacaaataat
    18841 gcagtttgct gaccagtcag tttgcgctga ctggtcaatc tcgtacttat aaatccgcca
    18901 tcgccgcgcg acgattcggg aagaatgcga ggcgtcccgg gatcggttga atgcctgcgc
    18961 gagccatagt gcgcagtggc tggaattcca ggttgcacac gcgcagttca catccttcgg
    19021 gcagacgctt cacaaaacgc tggaacgcat caagaccacc agcatcaagt accggaacgg
    19081 catcccactt cagaatcaca atccgtttgc cttcaagacg tgactccagg tccgtgaata
    19141 agccttcagc ggcagcaaaa aacagcgggc caataacgcg cagaaccagg acatcgtctg
    19201 gaacgtctac gactaccggt gccaggcgag tcatacgtgc gatacgacgc ataaacagca
    19261 gcgatgccag cacgatcccc acgctgatgg caataaccat atcgaacagc acggtcagcg
    19321 acatgcacag cagcatgacg atgatgtcat ctttcggtgc atgacgcagc aagtcgacca
    19381 ctttgtgcgc ttcactcatg ttccacgcca ccatcaacag cagggctgcc atggcggaaa
    19441 gtggcagcca ggagagcagc ggtgccagta ccagcagggc aagaataacc agaatagagt
    19501 ggatcaccgc cgagataggg gaagttgccc cggcacggac gttagcggca gaacgcgcga
    19561 tggcagctgt agcggtaatg ccaccaaaga acggagcgat aatattcccc agtccctgtc
    19621 caaccagttc gctgttcgcc ttgtgtttcg tcccggtcat accatccagc accacggcgc
    19681 agagcagaga ttcgattgcg ccgagcattg ccattgagaa tgccgcaggc agcagtgtgc
    19741 gaatagaatc ccaggttagc gtgaattctg aattaggcag atcccacggc agcaccagtt
    19801 gcggcagcag ttgcggaata ccgttaccct gagaaccatc ggccaggacg tagtggaatt
    19861 gcgaaccgat ggtagcaaca tgtccgccga gcaggttaac aatccccatc accgcgcaac
    19921 cagccagcaa ggccggaagg tggccgggta aacgtatgcc cagacgcggc cagaaaacca
    19981 gaatgccaag cgtcacaatg ccaatggctg catcacccac attaatggtc ggcagcgcca
    20041 taaataatgc gccgactttt tgtagataat gttccgggac atgggccatt tgcagaccga
    20101 gaaaatcttt aatctgcatg gtaccgatgg tgatcccgat acccgaggtg aaacctaagg
    20161 tgacggaaac cggaatatac tcaatcaggc gaccaaagcg tgccagcccc atcagaatca
    20221 aaaagatccc cgacagcaag gtcgcaacca gcagtcctgc cagtccaaac tgttgcgaaa
    20281 cgggatagag aattaccaca aatgccgcag tcggaccgga aacgctaaag cgtgaccctc
    20341 ccgtcagagc aatgacaatc cccgcaacag ctgcggtata taaaccgtac tggggtgcca
    20401 caccactacc aatagccaac gccatcgcca gcgggatagc aataatcccg acggttatcc
    20461 cggcaatcag gtcacgggta aaccgtgcgg cagtatattt ttctttccag caagcgtcga
    20521 tcagagcgcg gaaaggcatc acatgtgagg aaaatatttt gttcacaata atgtttcatc
    20581 cgtgagcgca tcatctgtca actaaatggc aggtgaagga ggcataggtc atacaaatgg
    20641 atattacaga caaaaaaacc cgccgcagcg ggtctttgag ccgggttcga ttagtgttcg
    20701 aacatggcag atatcgattc ttcgttgctg atacgacgaa tcgcttcggc cagcatacct
    20761 gacagggtca gagtacgcac gttcggcagt gatttgattt catcgctcag cggaatggta
    20821 tcgcagacaa cgacttcatc aattacagag ttacgcaggt tgttcgccgc gttgccagag
    20881 aagatcgggt gagtcgcgta cgcaaataca cgtttagcac cacgttcttt cagagcttca
    20941 gcagctttac acagcgtacc gccagtgtcg atcatatcat cgaccagtac gcagtcacga
    21001 cctgcaacgt caccgatgat atgcatcacc tgggaaacgt tcgcacgcgg acgacgtttg
    21061 tcgatgattg ccatatcggt atcgttcagc agcttagcga tagcgcgggc acgcacaacg
    21121 ccgccgatgt ccggagaaac cacaattggg ttatccagat tcagctgcag catgtcttcc
    21181 agcaggatcg ggctaccaaa tacgttatca accggaacgt cgaagaaacc ctgaatctgt
    21241 tcagcgtgca gatccactgt cagcacacgg tcaacaccga cgctggagag gaagtctgca
    21301 accactttcg cagtgattgg tacacgagcg gaacggacgc gacggtcctg gcgcgcatag
    21361 ccaaagtagg ggataacagc ggtgatacga cctgcggaag cacgacgcag ggcatcaacc
    21421 ataacgacta attccatcag gttgtcgtta gtaggggcac aagtggactg gatgatgaaa
    21481 atatcaccac cgcgtacatt ttcattaatt tgtacactga cttcgccgtc gctaaagcga
    21541 cctacagcgg cgtcgccgag tgaagtgtac aggcggttgg caatacgttg tgctagttcc
    21601 ggggtggcgt taccagcaaa aagcttcata tcaggcacga gaagaacctc aggcatgcgt
    21661 ccattggtgg aaagaatctg ccgaaaactg tgcgggccag gcatgattct ttccaggcgg
    21721 tgtattaaag agcgcgatgc aacgtctgga acaaggtgac gttgtcaccg aaactcagct
    21781 tgcccggctt aaagcatggc tctgtgcaat ggggaaagat taacgccttt cgccacaaag
    21841 ccattgagcc attccggggc ttgctctagc acctggcggg cttcagactc tgtatcaaat
    21901 tcagcaaaga cacaggcccc tgtcccagtc aggcgcgacg gggcgtattc taacagccag
    21961 gaaagcaccg catcaacctc gcgaaaacgt tttcttgcga taacctcgca atcattgctg
    22021 aattcacatt ttagcaacgt ttctattgac ctttttggcg tattgcgcgg gagttcagga
    22081 tctttaaaaa tcaccggtgt cggaatactt acaccagggt gcgccaccag ataccacttc
    22141 tctggcggat ccaccggcgt tagtatttca ccaacgcctt cggcaaacgc ggcatgacca
    22201 cgaacaaaga caggaacatc tgcgcccagc gtcagcccca tttccgccag ctcatccatg
    22261 cttagtccgc attgccagag atgatttaac gccaccagaa ccgtcgcggc attggatgaa
    22321 ccaccgccga gaccgccgcc catcggcaaa cgcttgtcaa tgctgatatt cgcaccgctt
    22381 cccgtcgaaa gacgcccgct gtctgccgca gttttcatca acaaccgcgc tgcgcgaacg
    22441 atcaggttat cttcatgttc cacgccttca acgggcgtta acagacgaat atccccatcg
    22501 tcacgaagct caatgctgat gatgtcgccg taatcaagaa actgaaacag cgtttgcagc
    22561 gtgtggtaac catccgcacg ctgaccggta atgtataaaa acagattaag ttttgccgga
    22621 gagggccact gtgtccgcat tatttcacta tccagttatc catttttaac ttgatgcgtt
    22681 gaccaccgtc ggtgagttcc atattggctg gcatcgcagg ttgagttttt gtgtcataac
    22741 caccgtaaac aactttccag tttttgccat tctggctgta ggtgatttcg ctcaggcggt
    22801 actggtcgtc cagtttgtaa tcggtcgcat cacccggtaa acctaaaatc cactggcgca
    22861 agctgttgag cggaatcggc attccggtta gtttaccaat catctcttcg gcgtcatcgg
    22921 cggtgtaacg ctgaccttta ttgtcgacta attgtacgtt acccggctga gcattcagct
    22981 ccagttccgt gctgcccaat gggttagtta acagcagacg atagcgatcc tggccggttt
    23041 gttgccagaa gaagcgagcg tacacttttt gttggtcgga aatataagcg aatgcaccgc
    23101 gagtctgata ctgattaaga ttacgcacgt cttgctggtg ctgacgccac tgtggcgaat
    23161 ccgggctttt gcctgggcct ttgggtgtgg taacagaaca ggcagtgagc acgagggcag
    23221 ctagcggtag caggcggata aagcgaaaat cgggcagggt cataataatg acaagtcctt
    23281 gagatacgtt gcagttataa cccttaatgc tagcgttacc gttagccatc gtctatgttc
    23341 acgttgtctt aattgccaga atctaacggc tttcggcaat tactccaaaa gggggcgctc
    23401 tcttttattg atcttacgca tcctgtatga tgcaagcaga ctaaccctat caacgttggt
    23461 attatttccc gcagacatga cccttttagc actcggtatc aaccataaaa cggcacctgt
    23521 atcgctgcga gaacgtgtat cgttttcgcc ggataagctc gatcaggcgc ttgacagtct
    23581 gctcgcgcag ccgatggtgc agggcggcgt ggtgctgtcg acgtgtaacc gcacagaact
    23641 ttatctcagc gttgaagaac gggatgacct gcaagaggcg ctcattcgct ggttgtgtga
    23701 ttaccataat ctcaacgaag acgatctgcg taatagcctc tactggcatc aggataacga
    23761 tgcggtcagt catttaatgc gcgttgccag tgggcttgat tctctcgtcc ttggcgagcc
    23821 gcagatcctc ggtcaggtta aaaaagcgtt tgccgattcg caaaaaggtc atatgaaggc
    23881 cagcgaacta gaacgcatgt ttcagaaatc tttctctgtg gcgaaacgcg ttcgcactga
    23941 aacagatatc ggtgccagtg ctgtgtctgt cgcttttgcg gcttgtacgc tggcgcggca
    24001 gatctttgaa tcgctctcta cggtgacagt actgctggtg ggtgcgggcg aaaccatcga
    24061 gctggtggcg cgtcatctgc gcgaacacaa agtacagaag atgattatcg ccaaccgcac
    24121 tcgcgaacgt gcccaaattc tggcagatga agtcggcgcg gaaattattg ccctgagtga
    24181 tatcgacgaa cgtctgcgcg aagccgatat catcatcagt tccaccgcca gcccgttacc
    24241 gattatcggg aaaggcatgg tggagcgcgc attaaaaagc cgtcgcaacc aaccaatgct
    24301 gttggtggat attgctgttc cgcgcgatgt tgagccggaa gttggcaaac tggcgaatgc
    24361 ttatctttat agcgtggacg atctgcaaag catcatttcg cacaacctgg cgcagcgtaa
    24421 agccgcagcg gttgaggcgg aaactattgt cgctcaggaa accagcgaat ttatggcgtg
    24481 gctgcgtgca caaagcgcca gcgaaactat tcgcgagtat cgcagccagg cagagcacgt
    24541 tcgcgatgag ttaaccgcca aagcgttagc ggcccttgag cagggcggcg acgcacaagc
    24601 cattatgcag gatctggcat ggaaactgac taaccgcttg atccatgcgc caacaaaatc
    24661 acttcaacag gccgcccgtg acggggataa cgaacgcctg aatattctgc gcgacagcct
    24721 cgggctggag tagcagtaca tcattttctt tttttacagg gtgcatttac gcctatgaag
    24781 ccttctatcg ttgccaaact ggaagccctg catgaacgcc atgaagaagt tcaggcgttg
    24841 ctgggtgacg cgcaaactat cgccgaccag gaacgttttc gcgcattatc acgcgaatat
    24901 gcgcagttaa gtgatgtttc gcgctgtttt accgactggc aacaggttca ggaagatatc
    24961 gaaaccgcac agatgatgct tgacgatcct gaaatgcgtg agatggcgca ggatgaactg
    25021 cgcgaagcta aagaaaaaag cgagcaactg gaacagcaat tacaggttct gttactacca
    25081 aaagatcctg atgacgaacg taacgccttc ctcgaagtcc gtgccggaac cggcggcgac
    25141 gaagcggcgc tgttcgctgg cgatctgttc cgtatgtaca gccgttacgc cgaagcccgc
    25201 cgctggcgtg tagaaatcat gagcgccagc gagggtgaac atggtggtta taaagagatc
    25261 atcgccaaaa ttagcggtga tggtgtatat ggtcgtttga aattcgaatc tggcggtcat
    25321 cgcgtgcagc gtgttcctgc tacggaatcg cagggtcgta ttcatacttc tgcttgtacc
    25381 gttgcggtaa tgccagaact gcctgatgca gaactgccgg acatcaaccc agcagatttg
    25441 cgcatagata ctttccgctc gtcaggggcg ggtggtcagc acgttaacac caccgattcg
    25501 gcaattcgta ttactcactt gccgaccggg attgttgttg aatgtcagga cgaacgttca
    25561 caacataaaa acaaagctaa agcactttct gtactcggtg ctcgcatcca cgctgctgaa
    25621 atggcaaaac ggcaacaggc cgaagcgtct acccgtcgta acctgctggg gagtggcgat
    25681 cgcagcgacc gtaaccgtac ttacaacttc ccgcaggggc gcgttaccga tcaccgcatc
    25741 aacctgacgc tctaccgcct ggatgaagtg atggaaggta agctggatat gctgattgaa
    25801 ccgattatcc aggaacatca ggccgaccaa ctggcggcgt tgtccgagca ggaataatgg
    25861 aatatcaaca ctggttacgt gaagcaataa gccaacttca ggcgagcgaa agcccgcggc
    25921 gtgatgctga aatcctgctg gagcatgtta ccggcaaagg gcgtactttt attctcgcct
    25981 ttggtgaaac gcagctgact gacgaacaat gtcagcaact tgatgcgcta ctgacgcgtc
    26041 gtcgcgatgg tgaacccatt gctcatttaa ccggggtgcg agaattctgg tcgttgccgt
    26101 tatttgtttc gccagcgacc ttaattccgc gcccggatac ggagtgtctg gtggagcagg
    26161 cactggcgcg gttgcctgaa caaccttgcc gtattctcga tctcggaacg ggtaccgggg
    26221 cgattgcgct tgcgcttgcc agcgagcgcc cggactgcga aattatcgct gtagatcgta
    26281 tgcccgatgc tgtcgccctg gcacaacgta atgcccagca tctggctatc aaaaatatcc
    26341 acattctgca aagcgactgg tttagcgcgc tagccgggca gcagtttgcg atgattgtca
    26401 gcaatccgcc gtatattgac gagcaggacc cacatcttca acaaggcgat gtccgctttg
    26461 agccgctcac tgcgctggtt gcggcagaca gtggaatggc agacatcgtg catatcatcg
    26521 aacagtcgcg taacgcgctg gtatccggcg gctttctgct tctggagcat ggctggcagc
    26581 agggtgaagc ggtgcgacag gcatttatcc tcgcggggta tcatgacgtc gaaacctgcc
    26641 gtgactatgg ggataacgag cgcgtaacgc tcggccgcta ttatcaatga caagtttttc
    26701 tacgttgctt agcgttcatc tcattagtat cgcgctttct gttgggctat tgaccttacg
    26761 tttctggcta cgttatcaga agcatccaca ggcatttgct cgctggacgc gcattgtgcc
    26821 gccggttgtc gatacgctgt tattgttaag cggcattgcg ttgatggcta aagcgcacat
    26881 ccagccattt tccgggcagg cacagtggct gactgaaaag ctgtttggag ttatcattta
    26941 tatcgttttg ggttttattg cactcgatta tcgtcggatg cacagtcagc aggcgcgcat
    27001 tattgccttc ccgctggcgt tggtggtgct gtacatcatc attaaactcg ccaccacaaa
    27061 agtaccgtta ctggggtaag tcatgagatc gttagctgat ttcgaattta ataaagcgcc
    27121 attgtgcgaa ggcatgatcc tggcttgcga agcaatccgc cgcgattttc cctcgcaaga
    27181 tgtttacgac gaactggagc gtctcgttag tctggcgaag gaagaaatta gccagcttct
    27241 gcctttagaa gagcagttgg aaaaactgat cgcgctgttt tacggcgact ggggatttaa
    27301 agcctcacgc ggcgtttatc gtctttccga tgcattatgg ctggaccagg tgttaaagaa
    27361 tcgacagggc agtgcggtat cattaggtgc ggttttatta tgggtcgcga atcgtctcga
    27421 tttgccgctg ctgccggtga ttttccctac gcagctgata ttgcgcattg aatgtccgga
    27481 tggcgaaatt tggctgatta atccttttaa cggtgaatcg ttaagcgaac atatgctgga
    27541 tgtgtggtta aagggaaata tcagcccgtc ggcggaactg ttttatgaag accttgatga
    27601 agctgataac attgaggtaa tccgcaaatt gctggataca ctcaaagctt cgttgatgga
    27661 agaaaatcag atggagctgg cgttacgcac cagcgaagct ttattacaat tcaacccgga
    27721 agatccctat gaaattcgcg atcgcgggtt gatttatgcg caactggatt gcgaacacgt
    27781 tgcgttgaac gatttaagtt atttcgttga acagtgtccg gaagacccga tcagcgaaat
    27841 gatccgtgcg caaataaata acatcgcgca taaacatatt gtgctgcatt aattaatcga
    27901 cattttactc aagattaagg cgatcctatg aaacaaaaag tggttagcat tggtgacatc
    27961 aacgtagcaa atgacctgcc gttcgtactg tttggcggta tgaacgtgct ggaatctcgc
    28021 gatctggcga tgcgcatttg cgagcactac gtaaccgtga cccagaaact gggtatccct
    28081 tacgtgttca aagcctcttt tgacaaagcc aaccgctcct ccatccactc ttatcgtgga
    28141 ccgggcctgg aagaagggat gaaaatcttc caggagttga agcagacttt tggcgtgaaa
    28201 attatcaccg acgttcacga accaagtcag gcacagcccg ttgctgatgt cgtggatgtg
    28261 attcagttgc cggcgtttct tgctcgccag actgacctgg ttgaagccat ggcgaaaacc
    28321 ggtgcggtaa ttaacgtcaa gaaaccacag tttgtcagcc cgggacagat gggtaatatc
    28381 gttgataaat tcaaagaagg cggcaacgaa aaagtgattc tttgcgatcg cggtgctaac
    28441 ttcggctatg acaacctggt tgtcgatatg ctgggcttca gcatcatgaa gaaagtgtct
    28501 ggtaattcgc cggtgatttt cgacgttacc cacgcactgc aatgtcgcga tccatttggc
    28561 gcagcttccg gcggtcgccg tgctcaggtg gctgagctgg caagagccgg tatggcggta
    28621 ggtctggcgg ggctgtttat tgaagcgcat ccggatccgg aacatgcgaa atgtgatggt
    28681 ccatccgcgc tgccgctggc taaactggaa ccgttcctca agcaaatgaa agcgattgat
    28741 gatctggtga aaggtttcga agaactggat accagcaagt aatctttttt gcctgaaaaa
    28801 taaagtctta gcgttctgcg ttaagacttt tttcatgggt gccggataca aaaaaggccg
    28861 caggctgtta cccctgcggc cggtttcggg cgcatattgc catcacggca gcctgacgcc
    28921 cgttttcacc ttacttccgg ttacgccacc agctgacaat cactgcggta ataatccccg
    28981 ccaggatcgg tgccgccagg ttgtgccaga aaatcatggc aaactgcgcg agcgtcatat
    29041 agccgccttg ttgtaatgac aacattttgc ggctattctt gaattgttct ggttcaagat
    29101 tagcccccgt tctgttgtca ggttgtacct ctcaacgtgc gggggttttc tctttccagc
    29161 aaccaatgcc accagggata aagcccccgc aacattgcgc ctcaccggat aacgccggct
    29221 tggtgtggat actacgtcgc aattcatctt cacttcatcc ctgaaatgtt tgcaataaag
    29281 agtacattcc ggtttttcaa cagctgttgc agtcatttcg tgcaggttgt ggtacaggct
    29341 tgcaattctg attaacaacc tgtccagcta gtatgaagaa atataataag caggaattta
    29401 tattatctcc cccgatttcc gtcatcggag gagatataac tgtcaggcaa atatcgtcat
    29461 caaataggcg gcaaacagtg ccagatgcgc tgcgccattg agcacgttag ttcgtccggt
    29521 ggagaaggag atatggcaca gtactaaaga ggccaccatc accaccattt ctggcgcacc
    29581 aagtgcaaac tgcaattcgt tacccgtcat aaaggcaatt agcgtgacga caggtacggt
    29641 aagcgaaatg gttgccaaca ctgaaccaaa gaacagattc atcgcgcgct ggacctggtt
    29701 attcaacact gcttttaacg cacctaaacc ttccggcgac agaatcaaca gagccaccag
    29761 gaagccagta aaggcgacag gcgcattcat gctgtcgagc aatgtctcca gcgggctggc
    29821 gttcattttg gtgactgcaa taacggcaat cagatggaca atcaaccaga tggcatgcca
    29881 caggctgcta tgggcagacg gtttaccgtg gtgcgggtcg tcatcatcac tgtcatcttc
    29941 gtgctcgtag acaaacaaac tttgatgcgt tttggtctgg atcagcaaaa atacgccata
    30001 cattgccgca gaaattaatg ctaccagtaa cgcctgacct gttgaaaaat tcgccgcagg
    30061 cagagccatt ggaaatacca gtacgattat cgccaggggg aacagcgcaa ttaaatactg
    30121 cttgatacca aacagattca tatattgggt ggcaaactta cgtccgccca acaataatga
    30181 aaagccaacc agcccacctg taacaatcat aatgattgaa tagagcgtat cacgcattag
    30241 cgttggcgcg gcatcgccgg ttgccattaa agctgaaatc aaactgactt caagaataac
    30301 cactgaaagg ctaagaataa gcgaaccgta aggttctccc aggcgatggg ctaatacgtc
    30361 cgcatgacgg acaacactaa aggcgctact taaaatacca ataagcgcaa gaagattgat
    30421 ggcaatgacc actggtagtg tctggctgct tccccacagg aacagcacta ccagcgccag
    30481 aaccgggaaa ataagcgaag tctccttgtg gcgggttttt accgcctctt gagcatttga
    30541 cattatggtt atccctttgc agatgaattt atcgaaaatg taaaaaatag gtaggaaaaa
    30601 taacagaaat tgtctggata tcggtaacat tttacgaatt tttaccccgc tgtcggtttt
    30661 ttactcattt gggcataaaa attagtaata cgtttagaca atgtttgttt tagcacttct
    30721 taagaagagt ctgacatgaa aattcttatg ttttggcaag agtagatatt gttgaccaca
    30781 cttaatgttc aactttgtaa aaggagtcaa cgatgtcgta taaaacgaaa agcgatctgc
    30841 cggaaagcgt aaagcacgtg cttccgtctc atgcccagga tatctataaa gaagcgttca
    30901 acagcgcatg ggatcaatat aaagataaag aagatcggcg tgatgacgcc agtcgcgaag
    30961 aaacagcgca taaagtggcc tgggctgctg tgaagcatga atatgccaaa ggggatgatg
    31021 ataaatggca taaaaaatcg tcaaaccggt agcttagtta aagctattcg tgcggtgttg
    31081 ccttgcaagt ggtccgtgga ttgcatattg tcccgttagt ggtttcaaaa tgagcagtaa
    31141 aaatgtccgg aagacaccaa aaagttgtcg cagggaagta tgcagtggcg gaggtgtaag
    31201 gtgataacgc gtgatttctt gatgaatgcc gattgtaaaa cggcatttgg tgccattgaa
    31261 gaatcactct tatggtcagc agaacaacgg gcggcttcgc tggcggcgac gctggcttgt
    31321 cgacctgatg agggaccggt gtggatcttc ggttatggat cgttgatgtg gaatccggca
    31381 ctggagttta ccgagtcgtg caccggtaca ctggttggat ggcatcgcgc gttttgcctg
    31441 cgtctgaccg ccgggcgcgg gactgcgcac cagccgggac gaatgcttgc actgaaagag
    31501 ggcggacgca ccacaggcgt cgcctatcga ctgccagaag agacgctgga gcaggaacta
    31561 accctgctgt ggaagcgtga gatgattacc ggctgttatc tgccaacctg gtgtcagctt
    31621 gatcttgatg atggacgcac agtaaacgcc attgtgttta ttatggaccc gcgacatcca
    31681 gaatatgaat ctgacactcg cgctcaggtc atagcgccgt tgattgccgc ggcgagcggt
    31741 ccgctgggaa ccaatgcaca atacctgttt tcactggaac aggagcttat caaactggga
    31801 atgcaggacg atgggctgaa tgatttgctg gtatcggtaa aaaaactgct ggcggagaat
    31861 tatccggatg gtgtgttacg gccgggattc gcctgagtaa acttccctca tagtggggcg
    31921 tccgacgccc cctcaaacat taaaatgtga gcactttatc ggctgacagc gtccattgcg
    31981 ccagttcaac aagagtaccg atttccaccc catcaatcag aggaagtgta ctaatcccgc
    32041 gcccgtcggt acaggttttg cacaatttca ccggtacatt ctgagcggta aggatctcca
    32101 gcatttgctg aatgttgtag ccttcccctg gtttttgccc gcgcaacccg gctgtgaccg
    32161 catcagacat caggaacaga cgcagatcca gattgttctc ctgctctcgt aacgcaatgg
    32221 ccagccgcaa gctgttaaac aaggattcgc tcccgtaagg tgcgccattg gcaacgatca
    32281 cgattttttg cattatttac tcctgtattc agggaattag acactcatct tctatcttac
    32341 tgcttctgca gcgtctgacc aatcggtcac atttttaagg attttcctga aagcgcgaga
    32401 aaatacgaca aaaggtgcca gtaatcgtta ttctttaagg ctatggtttt tcatttttac
    32461 cggaagttac cgacgttttg agccgtttcg ttcctcgcat tattccgttt tatttactct
    32521 tgctggcggc aggcggtaca gctaacgcac aatctacctt cgagcaaaaa gcggcaaatc
    32581 actttgagaa tagcaatgat ggtctgccgg atttaggcat ggcacctgaa catcatgatg
    32641 gggaaaaaca ctttgctgaa attgtgaaag atttcggcga aaccagtatg aatgataacg
    32701 ggctggatac tggcgagcag gcaaaagctt tcgcattggg aaaagtccgc gatgcgctta
    32761 gtcaacaggt taatcagcac gtagagtcct ggctatcacc gtggggaaat gccagtgttg
    32821 acgtcaaagt ggataacgaa ggacatttca ccggcagtcg tggaagctgg tttgtgccgt
    32881 tacaagataa tgatcgttat ctcacctgga gccagcttgg tcttactcag caggatgatg
    32941 ggctggtgag caatgtgggc gttgggcaac gctgggcgcg cggcagctgg ctggtgggtt
    33001 ataacacttt ttatgacaac ttgctggacg aaaatcttca gcgagcgggc tttggcgctg
    33061 aagcgtgggg cgaatatttg cgactatcgg caaactttta tcagccgttt gctgcatggc
    33121 atgaacagac tgccacgcag gaacaacgga tggcgcgcgg gtacgacctg acagcccgga
    33181 tgcgcatgcc gttctatcaa cacctcaata ccagtgtcag cgtagaacag tattttggtg
    33241 atcgtgtcga tttgtttaac tctggtacgg gttatcacaa tcccgtcgcg ttgagtctgg
    33301 gattaaatta cacccctgtg cccttagtca ctgtgacggc ccagcataaa cagggtgaaa
    33361 gtggcgagaa tcaaaataac ctcgggctga atcttaacta ccgctttggt gtaccgctca
    33421 aaaaacaact ttctgcgggc gaggttgtcg aaagtcagtc gttacgtggt agtcgctatg
    33481 acaatccgca gcgaaataat cttccgactc ttgagtaccg acagcgaaaa acgttaacgg
    33541 tgtttctggc gacaccgccg tgggatctaa aacctggcga aacagtgccg ctgaaattac
    33601 aaatccgcag tcgttacggt attcggcaac tgatttggca gggcgatacg cagatattaa
    33661 gtttgacgcc gggcgcacaa gccaacagtg aggagggctg gacgctgatc atgcctgact
    33721 ggcagaacgg ggaaggggcg agcaatcact ggcgattgtc tgtagtggtg gaagataacc
    33781 aggggcagcg tgtctcctcc aatgagatca cgctaacgct tgtcgaaccg ttcgacgcat
    33841 tgtcaaacga cgaactgcgc tgggaaccgt aatcagaaaa tgcgctcctg atgcacccat
    33901 accgcagctt ccacgcgaga ctttagcttc attttcttca gcatgtgctt gacgtgaact
    33961 tttactgtgc tttcggtgat gtccaggcgg cgggcaatca tcttgttcgg caaaccctgg
    34021 gcaatcagct tgagaatatc gcgctcgcgt ggggttaact ggttaacatc gcgctcagta
    34081 gtggcacggt tagcgcgcaa gctggcggcc agaacaggcg ttaatgcttc gcttaatacc
    34141 atttcgccag cagctgcctg atgtaacgct ttcagcagat cttccggttc catatctttt
    34201 aacagatagc catccgcgcc gcgtttcagt gcggtgacca catcttcttc atggttagag
    34261 acgctgaata ccacaatgcg cccggagagg gacttttcgc gcagtttatc cagcgtttcc
    34321 agaccgttca tgccgggcat attgagatct aacaggatca gatcgggatc aagagactcc
    34381 gccagttcaa taccctgttc gccattactc gcttcgccaa ccacagtgat atctggtgcc
    34441 atactgataa gctgttttac gccagttcgc aacatcgggt gatcgtcgat cagcaggata
    34501 gtagccggtt cctgattact catgggtatc tccttggacg tctgtgaaag ttttttcggg
    34561 aataaaggtg accaccactt cggtgccacc tgattcacga cggcggacgc ggcaatcgcc
    34621 tcgtaaactt tgcgcacggt cgcgcattat tatcatgccg tagtgattgc tgcggatggc
    34681 attttcaggc acgccgcagc cgttatcctg gacggtcagt ttgacctgat tatcgttttg
    34741 cgccaccgtc accacgacct cactcgcttg cgaatgtttg agggcgttac ttaatgcctc
    34801 acgggcaatt tgcaacaagt ggattgcctg atgcgaaggc accagacgag gcggcaattg
    34861 ataatccagc ttcaccggga agccaaattt ggcgctgtac tcttcgcaac tcgcctccag
    34921 cgccggacgt aatccaggct cggtgagctg caaacggaat gtggtgagca attcacgcaa
    34981 ctgcacccag gatgcattca gttcgttacg gatctgactt aacagttcgc ggctgctttc
    35041 tggcagcgca tcgccctgca tctgtaagca actcacctgc atcttcatgc aagagagaga
    35101 ttgggcaata gaatcatgca gttcgcgcgc aatggtggca cgctcttcca tcacgatcaa
    35161 ctgttgctga cgttcctgat ggcgatccag cgccagcgtg gcggtgagtt gttcaaccag
    35221 ggtatccacc agttgttgtt gatcatggct aagatgacgc ccctgcggca gggtcgccag
    35281 caaaataccg tactgcgtat gagtgtcagc cagccgccac ttcagggttg tgccgcgatc
    35341 gccaacgggt aatacgccgc gcgggcagag ctggcagcct ttatcatcac aagtcatatc
    35401 tgactggcag gtaaactcct gatgattctc ttcatcatca gtgtcataca cccgcagttc
    35461 gatatcacgt agcagggtta aattctgtaa gccgttgagt acaggtgaca ggcgttcaca
    35521 cagcggggcg cgggaatgca aacggcggtt agcctgccat aaaaaagaga ggatctgatt
    35581 tttatgctcc agcccagcgg ttttctcctg aacccgctgc tcaagtacgg cataactttc
    35641 cgccagttct gcagacatat tgttcaacgc agttccaagc atcgccattt cgttgcgccc
    35701 gctgatgttt gcgcgttggg taaaatcgcg atggctgacg gcactcgcca ttgccagcag
    35761 ttgccgccac ggttgtagca atctcgcccg caaccagata atagtgaata ccagtaaaag
    35821 tgccataaat accgccatta cccgatggac cagcaccact gtctcaatgc gcatttccgt
    35881 ggtgcgatca aaaccagata ccagctgatc aagcccggca acaaactggc tgacatccgc
    35941 tgacaccgtt tcgcggtttt gtgcacgtat cagtgcaggg atcagttcat tacgccagta
    36001 atcttgtaaa ccctgtaatt gcgccagttg cccgtctcgt tctgctgctc gagtcaactc
    36061 ggcgctaaat gctgtttgtt ccatctcttt aattaagggc ttgtctttct cgcttaatgg
    36121 cactgctgcc aacagacggt aactttgcat gcgcagcgat cccgctttgt tgatcgcatg
    36181 ggcgctgccc tgaacgcctt gcaccagcca gccagaaacc gccatccctg ccagtccaat
    36241 agcagtagaa agcaacacaa taagcgcaac ctgattaacc agggtgagcg gagagagaca
    36301 acgtttaagc atgtaaacct cttccttcag gctttaaatg agcaataacc ttaatgaatg
    36361 tgacgataca ttctggaatg gcagtattct cggctattgg ctgaagtata cccatacccg
    36421 gaaagagtta ctccttattt gccgtgtggt tagtcgcttt acatcggtaa gggtagggat
    36481 tttacagtac cgtgaaaaat ctcataattt ttatgaaatc actgtactca ctatggataa
    36541 tgataaatat caatgataga taaagttatc ttatcgtttg atttacatca aattgccttt
    36601 agctacagac actaaggtgg cagacatcga aacgagtatc agaggtgtct atgagtcact
    36661 catccgcccc cgaaagggct actggagctg tcattacaga ttggcgaccg gaagatcctg
    36721 cgttctggca acaacgcggt caacgtattg ccagccgcaa cctgtggatt tccgttccct
    36781 gtctgttgct ggcgttttgc gtatggatgt tgttcagcgc tgttgcggtg aacttaccga
    36841 aagtcggttt taattttacg accgatcagc tatttatgtt gactgcgctg ccttcggttt
    36901 ctggcgcgtt attacgtgtt ccatactcct ttatggttcc tatctttggt ggtcgtcgct
    36961 ggacggcgtt cagcaccggt attctgatta ttccttgcgt ctggctgggt tttgccgtgc
    37021 aggatacctc cacgccttat agcgtcttca tcatcatttc tctgctgtgc ggctttgctg
    37081 gcgcgaactt cgcatccagt atggcaaaca tcagcttctt ctttccgaaa cagaagcagg
    37141 gtggcgcgct gggtctgaat ggtggtctgg gcaacatggg cgtcagcgtc atgcagttgg
    37201 ttgctccgct ggtggtatca ctgtcgattt tcgcagtatt tggtagccag ggcgtcaaac
    37261 agccggatgg gactgagctg tatctggcga atgcgtcctg gatatgggtg ccgttccttg
    37321 ccatcttcac cattgcggcg tggtttggca tgaacgatct tgctacctcg aaagcctcca
    37381 tcaaggagca gttgccggta ctcaaacggg gtcatctgtg gattatgagc cttctgtatc
    37441 tggcaacctt cggctccttc atcggcttct ccgcgggctt tgcgatgctg tcaaaaacgc
    37501 agttcccgga tgttcagatt ctgcaatacg ctttcttcgg gccgtttatt ggtgcgctgg
    37561 cgcgttctgc aggtggtgca ttatctgacc gtctgggcgg aactcgtgtc acgctggtga
    37621 actttatcct gatggcgatt ttcagcggcc tgctgttcct gaccttaccg actgacggac
    37681 agggcggaag cttcatggcg ttcttcgcag tcttccttgc gctgttcctg accgctgggc
    37741 tgggtagtgg ttccactttc cagatgattt ccgtgatctt ccgtaaactg acaatggatc
    37801 gcgtgaaagc agaagggggt tctgacgaac gtgcgatgcg tgaagcggca accgacacgg
    37861 cggcggcgct gggtttcatc tctgcgattg gcgcgattgg tggcttcttt atcccgaaag
    37921 cgtttggtag ctcgctggca ttaacgggtt cgccagtcgg cgcaatgaaa gtatttttga
    37981 ttttctatat cgcctgcgtg gtgattacct gggcggtata tggtcggcat tctaaaaaat
    38041 aaatcgtaat atttgattat cctttgcgcg gcatgatgtc gcgctttttt tatgcgtcat
    38101 ttagttacaa catactaatg ttgtatggct tatttcgctg gatttcatta agagtcatta
    38161 atatgttacc catggggaat actccttaat acccatctgc ataaaaatct taatggttta
    38221 aataaccaca ggtgtaaaac gtc
//
LOCUS       DAFGPF010000038        38069 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFGPF010000038 DAFGPF010000000
VERSION     DAFGPF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38069
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.038"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(204..1118)
                     /locus_tag="LSX49_002156"
     CDS             complement(204..1118)
                     /locus_tag="LSX49_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7168560.1"
                     /translation="MGKTFSIKVLFGIYLLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVILPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKSGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNSVVMPTGGCTVDSRNVTVNLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSARQVFANTAPDATKASGVGVSLMRNGKTLATGENVSLGTVNKSKVPLG
                     LSATYGQTGNKVAAGAVQSVIGVTFIYE"
     gene            complement(1178..1681)
                     /locus_tag="LSX49_002157"
     CDS             complement(1178..1681)
                     /locus_tag="LSX49_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7168561.1"
                     /translation="MKRLHKRFLLATFCTLFTATLQAADVTITVNGRVVAKPCTIQTK
                     EANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPIETSAVTAIVTGSTDNTGYYKNEG
                     TAENIQIELRDDQDATLKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALI
                     NVIYIWQ"
     gene            complement(1694..2224)
                     /locus_tag="LSX49_002158"
     CDS             complement(1694..2224)
                     /locus_tag="LSX49_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7168562.1"
                     /translation="MKYNNVIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDGNMRPVKLNDLHTGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVSASATFTLEFQ"
     gene            complement(2238..4889)
                     /locus_tag="LSX49_002159"
     CDS             complement(2238..4889)
                     /locus_tag="LSX49_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBL7168563.1"
                     /translation="MTAFRAAFKAYRMHQVLILPRFARLTFALGLATAVFPVDAEYYF
                     NPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLNDEFMASRDITFIADDNNADLIP
                     CLSTDLLVSLGIKKSALLDNKEHSADKHVPDNSACTPLQDRLADASSEFDVGQQHLSL
                     SVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQS
                     GINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHINTSAERDIIPLRSRLTVGDSYTDGD
                     IFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTAQVSVKQNGYDVYQTTVPPGP
                     FTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGN
                     NLQSSPKFVQASLMHGLKGNWTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQAN
                     TTLADDTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFYNLSDSAYSRMSGYTVK
                     PPTGDTSEQTLFIDYFNLFYSKRGQEQISISQQLGHYGTTFFSASRQSYWNTSRSDQQ
                     ISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNA
                     SYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTQGGNTSSGTSGYSSLNYRGAY
                     GNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQT
                     GIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQ
                     IGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGNDK
                     NSNCIVDYKLPAVSPGTLLNQQTAICR"
     gene            complement(4931..5641)
                     /locus_tag="LSX49_002160"
     CDS             complement(4931..5641)
                     /locus_tag="LSX49_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBL7168564.1"
                     /translation="MQTTRTPYSVSFMATVLLLFLFACHSTIANAAVALGATRVIYPA
                     NQKQVLLPVTNNDPASVYLIQSWIENAGDQKDTQFVITPPLFSMQGKKENTLRIINAT
                     NHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTHLAMAPEEAPA
                     MLRFRRSGSILTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAVTGDISF
                     QTINDYGALTPLIKATMQ"
     gene            complement(6003..6566)
                     /gene="fimA"
                     /locus_tag="LSX49_002161"
     CDS             complement(6003..6566)
                     /gene="fimA"
                     /locus_tag="LSX49_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HBL7168565.1"
                     /translation="MKLKHVGIIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGE
                     VVNAACAIDSESMNQTVELGQVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAF
                     LGTTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLVLDGATFSAKTDLIDGTNILP
                     FQARYIALGQSVAGTANADATFKVQYL"
     gene            complement(7477..8799)
                     /gene="hipA"
                     /locus_tag="LSX49_002162"
     CDS             complement(7477..8799)
                     /gene="hipA"
                     /locus_tag="LSX49_002162"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system serine/threonine
                     protein kinase toxin HipA"
                     /protein_id="HBL7168566.1"
                     /translation="MPKLVTWMNNQRVGELTKLANGAHTFKYAAEWLASRYARPLSLS
                     LPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVT
                     LIPEDETVTCPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTAL
                     LRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVP
                     DAEIIKAGRVRALAVERFDRRWNTERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIA
                     QIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDII
                     SAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLKFPEVQMHEIL
                     SDFARMIPAALDNVKTSLPTDFPENVVTAVETNVLRLHDRLSREYGIK"
     gene            complement(8799..9065)
                     /gene="hipB"
                     /locus_tag="LSX49_002163"
     CDS             complement(8799..9065)
                     /gene="hipB"
                     /locus_tag="LSX49_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HipB"
                     /protein_id="HBL7168567.1"
                     /translation="MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISN
                     FENNPDNTSLTTFFKILQSLELSMTLCDAKNASPEATEQQDLEW"
     gene            9373..10131
                     /gene="tam"
                     /locus_tag="LSX49_002164"
     CDS             9373..10131
                     /gene="tam"
                     /locus_tag="LSX49_002164"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HBL7168568.1"
                     /translation="MSDWNPSLYLHFAAERSRPAVELLARVPLENIEYIADLGCGPGN
                     ITALLHQRWPAARITGIDSSPAMIAEARSALPDCLFVEADIRNWQPEQALDLIFANAS
                     LQWLPDHYELFPHLVSLLNSHGVLAIQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQHFL
                     TRYHQMLEEQYPLQENGQILLAFPRLFIVARRTE"
     gene            complement(10135..11049)
                     /locus_tag="LSX49_002165"
     CDS             complement(10135..11049)
                     /locus_tag="LSX49_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HBL7168569.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIVFAHCLRMTLRKQPQAEVLAHYLKTEDLQRVLASNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(11246..12697)
                     /gene="uxaB"
                     /locus_tag="LSX49_002166"
     CDS             complement(11246..12697)
                     /gene="uxaB"
                     /locus_tag="LSX49_002166"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBL7168570.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFA
                     LAALIAFYRGVRNGETYPVQDDAHWLERYQQLWSQYRDRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            complement(12924..14342)
                     /locus_tag="LSX49_002167"
     CDS             complement(12924..14342)
                     /locus_tag="LSX49_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBL7168571.1"
                     /translation="MHVQPISTFRLFQEGHLLRNSIAIFVLTTLFYFIGAELRLVHEL
                     SLFWPLNGVMAGVFARYVWLNRLHYYAISYVAMLVYDAITTEWGLVSLAINFSNMMFI
                     VTVALLVARDKRLGKNKYEPVSALRLFNYCLLAALLCAIVGAIGSVSIDTLDFWPLLA
                     DWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAF
                     PLPALIWCAVRYTPQVTCLLTFVTGAVEVVLVANSVIDISVGSPFSIPQMFSARLGIA
                     TMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEALKSPSLKQTQHLTV
                     MLLDIDYFKSINDNYGHECGDKVLSVFAQHIQKIVGDKGLVARMGGEEFAVAVPSVNP
                     VDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGCASYRTLTDDFNKLMVEADTC
                     LYRSKKDGRNRTSTMRYGEEVV"
     gene            complement(14481..14840)
                     /locus_tag="LSX49_002168"
     CDS             complement(14481..14840)
                     /locus_tag="LSX49_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HBL7168572.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGVKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGEALSEEQQR
                     YIVTVIYHWLVIQMNQP"
     gene            complement(14840..15766)
                     /gene="glsB"
                     /locus_tag="LSX49_002169"
     CDS             complement(14840..15766)
                     /gene="glsB"
                     /locus_tag="LSX49_002169"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HBL7168573.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            complement(15830..17218)
                     /gene="sad"
                     /locus_tag="LSX49_002170"
     CDS             complement(15830..17218)
                     /gene="sad"
                     /locus_tag="LSX49_002170"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HBL7168574.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGVDDIENALQLAAAGFRD
                     WRETNIDYRAEKLRDIGKALRARSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLVAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEDNALGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITIAKDAEHALELANDSEFG
                     LSATIFTTDETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRV"
     gene            17319..18200
                     /locus_tag="LSX49_002171"
     CDS             17319..18200
                     /locus_tag="LSX49_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7168575.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNRRYPKIQFSLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGHAPVTRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVVAGAGIALIPRSMLESMPGHHQVESWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDAPDSAKQGYQ"
     gene            18278..18361
                     /gene="yneK"
                     /locus_tag="LSX49_002172"
                     /pseudo
     CDS             18278..18361
                     /gene="yneK"
                     /locus_tag="LSX49_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
     gene            18539..19729
                     /gene="ydeA"
                     /locus_tag="LSX49_002173"
     CDS             18539..19729
                     /gene="ydeA"
                     /locus_tag="LSX49_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HBL7168576.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAHSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIGALLTLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(19754..20419)
                     /gene="marC"
                     /locus_tag="LSX49_002174"
     CDS             complement(19754..20419)
                     /gene="marC"
                     /locus_tag="LSX49_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HBL7168577.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EVKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            20631..21065
                     /gene="marR"
                     /locus_tag="LSX49_002175"
     CDS             20631..21065
                     /gene="marR"
                     /locus_tag="LSX49_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310164.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HBL7168578.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     SGAAICEQCHQLVGQDLHQELTKNLTADEVATLEHLLKKVLP"
     gene            21086..21469
                     /gene="marA"
                     /locus_tag="LSX49_002176"
     CDS             21086..21469
                     /gene="marA"
                     /locus_tag="LSX49_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HBL7168579.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNN"
     gene            21501..21719
                     /gene="marB"
                     /locus_tag="LSX49_002177"
     CDS             21501..21719
                     /gene="marB"
                     /locus_tag="LSX49_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HBL7168580.1"
                     /translation="MKPLLSAIATALILFSAQGVAEQTTQPVVTSCGNVVVVPPSQEQ
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(21750..22649)
                     /gene="eamA"
                     /locus_tag="LSX49_002178"
     CDS             complement(21750..22649)
                     /gene="eamA"
                     /locus_tag="LSX49_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416050.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HBL7168581.1"
                     /translation="MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVA
                     FPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIV
                     LGAFTFGERLHGKQLTGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNI
                     FNKKIMSHATRPAVMSLVIWSALIPIIPFFAASLILDGSATMIHSLVTIDMTTILSLM
                     YLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFFGAV
                     LIMTGLYINVFGLRWRKAVKVGS"
     gene            22844..24031
                     /gene="ydeE"
                     /locus_tag="LSX49_002179"
     CDS             22844..24031
                     /gene="ydeE"
                     /locus_tag="LSX49_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HBL7168582.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTFCFVIGLVGFIFSGNSLLMWGMSAAVFTVGEIIYAPGEYMLIDHIAPPGMKAS
                     YFSAQSLGWLGAAINPLVSGIVLTSLPPFSLFIILALVIVVAWVLMLKGIRARPWGQP
                     ALC"
     gene            24158..24253
                     /gene="mgtS"
                     /locus_tag="LSX49_002180"
     CDS             24158..24253
                     /gene="mgtS"
                     /locus_tag="LSX49_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HBL7168583.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            complement(24472..25362)
                     /gene="dgcZ"
                     /locus_tag="LSX49_002181"
     CDS             complement(24472..25362)
                     /gene="dgcZ"
                     /locus_tag="LSX49_002181"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HBL7168584.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTAALTDYKIYLLTVRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKATN
                     DEEACRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEG
                     KQTGRNRCMFIDEQNVINRV"
     gene            complement(25616..25720)
                     /locus_tag="LSX49_002182"
                     /pseudo
     CDS             complement(25616..25720)
                     /locus_tag="LSX49_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00156 family protein"
     gene            complement(25869..27914)
                     /gene="dcp"
                     /locus_tag="LSX49_002183"
     CDS             complement(25869..27914)
                     /gene="dcp"
                     /locus_tag="LSX49_002183"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707439.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HBL7168585.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQTPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLEQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNNWL
                     IPLLNTTQQPALAELRDRATREKLFTAGWRRAEKNDANDTRAIIQRLVEIRAQQAKLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNETHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGTAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGRRFREAILSRGNSEDLERLYRQWRGKAPQIMPMLQHRGLNV"
     gene            28051..28797
                     /gene="ydfG"
                     /locus_tag="LSX49_002184"
     CDS             28051..28797
                     /gene="ydfG"
                     /locus_tag="LSX49_002184"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HBL7168586.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWSNIDILVNNAGLALGMEPAHKASIEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            28886..29572
                     /gene="ydfH"
                     /locus_tag="LSX49_002185"
     CDS             28886..29572
                     /gene="ydfH"
                     /locus_tag="LSX49_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YdfH"
                     /protein_id="HBL7168587.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            29749..29952
                     /gene="ydfZ"
                     /locus_tag="LSX49_002186"
     CDS             29749..29952
                     /gene="ydfZ"
                     /locus_tag="LSX49_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HBL7168588.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(29988..31448)
                     /locus_tag="LSX49_002187"
     CDS             complement(29988..31448)
                     /locus_tag="LSX49_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL7168589.1"
                     /translation="MGNHLLSAKATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADIL
                     ATEHFSDWGYYEVNLIGGEQQIADLQQQDNLYTVAEMSADAWTARVVGVVKKALHVQI
                     DGLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVVADVQNPHQPKTATG
                     VIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAIDVKLAQWIEDNVTFP
                     STMVDRIVPAVTEDTLAKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGVE
                     LVSDVLPYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRHAAYTLMLQEQAP
                     TLKVQGVDLQDYANRLIERYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKF
                     DLLALGVAGWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGTARVQSLLAIKAIF
                     GDDLPDNSLFTTKVTEAYLSLLAHGAKATVAKYSVK"
     gene            complement(31537..32904)
                     /gene="ydfJ"
                     /locus_tag="LSX49_002188"
     CDS             complement(31537..32904)
                     /gene="ydfJ"
                     /locus_tag="LSX49_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter YdfJ"
                     /protein_id="HBL7168590.1"
                     /translation="MTIEKHERSTKDLVKAAVSGWLGTALEFMDFQLYSLGAALVFHE
                     IFFPESSTAMALILAMGTYGAGYVARIVGAFIFGKMGDRIGRKKVLFITITMMGICTT
                     LIGVLPTYAQIGVFAPILLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSFVA
                     MGTNCGTLSATAIWAFMFFILSKEELLAWGWRIPFLASVVVMVFAIWLRMNLKESPVF
                     EKVNDSNQPTAKPAPAGSMFQSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTLLFNK
                     AIPTDALMISSILGFMTIPFLGWLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYA
                     PSTIMVALIVIHNCAVLGLFALENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPIL
                     AGIFCTMTESWYPIAIMIMAYSVIGLISALKMPEVKDRDLSALQDAAEDQPHVVRAAQ
                     PSRSL"
     gene            complement(32962..33981)
                     /locus_tag="LSX49_002189"
     CDS             complement(32962..33981)
                     /locus_tag="LSX49_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HBL7168591.1"
                     /translation="MKSILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPL
                     GEIFDEKGIQPTLVIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            complement(33993..35207)
                     /gene="rspA"
                     /locus_tag="LSX49_002190"
     CDS             complement(33993..35207)
                     /gene="rspA"
                     /locus_tag="LSX49_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HBL7168592.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGEKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            complement(35413..35739)
                     /locus_tag="LSX49_002191"
     CDS             complement(35413..35739)
                     /locus_tag="LSX49_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HBL7168593.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            35874..36215
                     /locus_tag="LSX49_002192"
     CDS             35874..36215
                     /locus_tag="LSX49_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HBL7168594.1"
                     /translation="MKITLSKRIGLLAFLLPCALVLSTTVHAETNKLVIESGDSAQSR
                     QRAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVIIP"
     gene            36250..36810
                     /gene="speG"
                     /locus_tag="LSX49_002193"
     CDS             36250..36810
                     /gene="speG"
                     /locus_tag="LSX49_002193"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HBL7168595.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFTVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(36813..37523)
                     /locus_tag="LSX49_002194"
     CDS             complement(36813..37523)
                     /locus_tag="LSX49_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HBL7168596.1"
                     /translation="MKYKLLPCLLAILLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTLVALVLDANYYRDAET
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDNHANPVDCQLIIVDEG
                     VKPAVERVYTIKNTIDYY"
     gene            37631..37936
                     /locus_tag="LSX49_002195"
     CDS             37631..37936
                     /locus_tag="LSX49_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HBL7168597.1"
                     /translation="MKHSTYCAALLLALASPTVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSTQDGAPAEPQ"
BASE COUNT        10177 a         9376 c         8586 g         9930 t
ORIGIN      
        1 taaataatag agtagtataa atacgataag ttaagcatca tctctcatag ggtttaaatt
       61 aacataattc tcaatataaa aaataagact ctggcttcaa ttgtgcgcgg attttcttac
      121 aagtgtagga taatagcctt cacaaaataa ttatccgcgc aattttcgtg aatggagcgc
      181 atagactaat gtcaaaatca caattattca tagataaaag tgacaccaat gactgactgg
      241 acggctccgg ctgcaacctt atttcctgtt tgtccatagg ttgcgcttaa acccagaggt
      301 actttgcttt tatttactgt ccccagggag acattttctc ctgttgccag tgtttttcca
      361 ttacgcatca gagagacacc cacgcccgat gcttttgttg catctggtgc tgtgttagca
      421 aacacttgtc gggcactgtc agtggtggca cccgaaagat aaaatgagag cttttgttcg
      481 ctagagcaat atacaccaag gggtatttct gcgcttccag gaaagtccgg gagattcacg
      541 gtgacattac gactatcaac ggtgcaaccg cctgttggca taacaacact gttatttgaa
      601 ataatattcc acgtaaaatt acgtggattt ccgcttccta acgtggcaat tttatacata
      661 tgaatacggg caataacttc ccctgatttt atgacaactc caccggctgc tccgactggg
      721 gtaatataga gttttaacgg taatggcatc ggtgtcttat caccaatatc caatacgttg
      781 gtatttgtcg tcaacgggaa ggggtaggtc acattattcc agtacagtga tcctttatat
      841 gactgtaggg agcctgcgaa agctgatcct tgtaccaggt ttatatgatc agtgtcgtac
      901 cagccgccgt aatcattcca gcaacttata tgctgagaca agtctacaac cagattctgg
      961 cccggtagta ttacaggatc gagattaaca taaacagagg ttgtacctgc tccaatactt
     1021 gacccgccat cgacattaca actaaaggca aaaactttgc ctgccattaa tagaagataa
     1081 ataccgaaca ggacctttat actgaatgtt ttacccatga tatatcctaa ggttaaaaaa
     1141 ttgatttaaa aaggaggcaa ataaaatcaa attgatgtta ttgccagata tagatcacat
     1201 tgattagcgc ctcgatcgtt ccctggcttg cgtttccatt caccgtgata gctcttgcct
     1261 taagtggaaa ctgtgcatta cgagtgatct catcaacaat aaccgttttg ctatcgccat
     1321 tttttaacgt cgcatcctgg tcatccctta gctctatctg aatattttcg gcagtacctt
     1381 catttttgta ataacccgta ttgtcagttg aacctgtcac gattgccgtc actgcacttg
     1441 tttcaatcgg acaatcggtt aatgacaaag taatattgtg ccagccagat gcagaaccag
     1501 gttgttgcag attgcgtgta taaagatccc cgagattaac gttagcttct ttggtttgaa
     1561 tagtgcatgg tttagcgact acccgaccat taacagtgat agtgacatcg gcggcctgga
     1621 gagttgctgt aaataacgtg caaaacgtag ctaacaggaa cctcttgtga agtcttttca
     1681 tatctgactc tgattattga aattcaaggg taaaggttgc cgaagcgctc accagtcctg
     1741 gattgacgga cttctgagtt gacttcaaac gagcggagta aggcaaaata ttgttctgtt
     1801 ctggtaccaa tgggatccac tgcatcccgg tatgaaggtc attcaatttc accggacgca
     1861 tatttccgtc cagtatttct atacccaaac cggaggccgt attgcttcct tcatccagtt
     1921 tcaacagagt attattttct gcatcctcaa taccgttaaa tgcaacccgc acccccgttg
     1981 tccctttgct gcattcactt aacgtaatct gaaaagggac ggcaggactt gtgctaccgg
     2041 tcgttggaaa ttgtctggca ctgttttttt ggagatctac ggtaaaatta agcgaatccg
     2101 atgagactgt gcagccataa tcgagaacgc gcccgctaat tttaataacg ctatctgcgg
     2161 ataaagcaga ataggtggtt aaccccagac ataaaccgag gaaaataacg ttattgtatt
     2221 tcataatcta ttgttcctta gcgacagatt gctgtctgct ggttcagcaa ggttccagga
     2281 gagactgcag gaagcttgta atcgacaata cagtttgagt ttttatcatt gccccatgaa
     2341 acctgtaatt tccctgactg tggaagtcca gtcagataaa cctgaccatt ttccgcgaca
     2401 atgctgccat ttttattctc tccgtgagtg acaattgcac cgaatggaac gcttttatta
     2461 ccgtacttca acgtcattaa tactttcccg ccgatttgtg cattaaatgt tgctctggca
     2521 atagcaccgt gagttgggat gacagtgact acggtttcat ccagttcaac attatctgca
     2581 agggaattcg cgttaagagc gacacgattt tctctatatt ctgtcgcaaa tggtaatatg
     2641 gcatagccac gccagtcggt atgaattccg gtctggttct ctattttgac attatcagcg
     2701 ccaggagcct taaccagaac cattgtgtcg cccagcggct gtccaaaggt gatgccatca
     2761 gcatgagcaa taatcccacc actcattccg taataaatct ggctgctgtc accactccga
     2821 ctgtaaccga cattcgtatt accgtaagct ccacgataat taagagaact gtaaccactg
     2881 gtgccagacg atgtattacc cccttgggtg ttaccgacct gaacgctata attcaggtta
     2941 ttatccggca gcagagtgcc ataaacccct gataggttgg tcatgccgcc tttcaaatcg
     3001 tttgacatac tgtaactggc gtttgaatta cgaaatgccg actgactgtc tgtacgcatc
     3061 caatgactaa agggaacatt aagtgtaaaa gcgagtaaat gatcccgatc gttttgccat
     3121 atattattgg aatagctgta attcagcgaa gtcgtaatat caccaaacgg cacatttaat
     3181 ccaaatgata tttgctggtc gctgcgtgac gtgttccagt aactttggcg actggcactg
     3241 aaaaatgtcg taccgtaatg tccaagctgc tgagagatgc ttatttgttc ctgaccacgc
     3301 ttactgtaga acagattaaa ataatcaata aatagtgtct gctcactggt gtctccggta
     3361 ggaggcttga cggtgtaacc actcattcga ctgtatgcac tgtcggataa gttataaaaa
     3421 ccttgcgtag aatagcgata tcctgcgacc tggatattgg ttcccgtctg gtagaaggat
     3481 ttgctgtaga cggatttaac cgattgtccg ctgtgacggg tgtcatctgc aagcgtcgta
     3541 ttggcctgcg tgatatcgaa agaaaaggca ccaaaaagtc ctaaatcttt accaatacca
     3601 aggttgaagg cctgataatc ttctgcaatt tgcattccgc cataaggtgt ccagtttcct
     3661 ttcagaccat gcatcaagct tgcttgtacg aacttggggg agctttgcag gttattccca
     3721 ctacgatatt cccccatggc aagtgcataa cgcgtatatc cagcacgttg gagaaccgga
     3781 acagacgaat aaggaacata taatgtctga atactgccgt ctgcctcttt tatggttact
     3841 tgcagatcac caccattggc cgcagagttg atatcatcaa tagtaaaagg gccgggtggg
     3901 acagtagtct gataaacatc gtatccattc tgttttacac tcacttgtgc ggtgccacga
     3961 gcaataccat gaatcaccgg agcgaaacca tgttggctat cgggcaacat cgcttctgtt
     4021 gaatttattt taaggccacg aaagttcaca ctgtcaaaaa tatcgccatc ggtataacta
     4081 tcacccactg ttaaccgtga gcgtaacgga ataatgtcac gttcagccga cgtattgata
     4141 tgctgccatt tattgctgtc agatgaattg ctactcccac tgttataact ccacgttgag
     4201 ttatcgcgca gtcgccaact accaatgttg atgccactct gtaaattcaa atatgcatag
     4261 ttggattttc ctgcattatg gttactacgg ttattaatag aattaccatt aaaactatag
     4321 tttagtagcc cggcatttat tccttcttcc cacagatcag gagaaacata gccgcgagcc
     4381 attctgccga catatatttg cggaacggag agtgacagat gttgctgacc aacatcaaac
     4441 tcagatgatg cgtcagccaa acgatcctga agtggtgtgc atgcgctgtt gtccggcaca
     4501 tgtttatctg ccgaatgttc cttgttgtct aataatgctg atttttttat gccaagactg
     4561 acaagaaggt ctgtactcag gcatgggatg agatctgcgt tattatcatc tgcaataaaa
     4621 gtaatatccc gactagccat aaattcgtcg ttcaaataaa tgtcgacccg atatgtacca
     4681 ggtggggcct cgcgtccctt agtaaaggca gataaatcga cagattcagc aaggtcattg
     4741 cttaaaaacc gtggattaaa ataatactct gcgtcaacgg gaaaaaccgc agttgctaag
     4801 ccaagggcaa aggtaagccg tgcaaagcga ggcagtatta acacctgatg catacgatat
     4861 gccttaaatg cggcacgaaa ggctgtcatt tttaatcccg attgagttta ttattaatta
     4921 ggtcactggc ttactgcatg gttgccttaa taagcggagt taatgcaccg taatcattga
     4981 ttgtctgaaa actgatatcc ccggttacag catgcgggat atccaccgat acttcacctt
     5041 ttggcggcac catggtgttt gggagattgc tatttcctgc tttcatattt gttacggtaa
     5101 tgaagtaggg cgttggatta ataagagtga gtatgctacc gctgcgacga aaccgaagca
     5161 ttgcaggcgc ttcttcaggt gccattgcca gatgcgtggg gcgataaaac atttttatgc
     5221 ggctaataat tgccagctgt aatgtattct cattcttctg gtctttttcc atagcaggga
     5281 tagctttaac attaacccag aacaggcttt cacggtcgcc tggtaactga tgattagtgg
     5341 cgttgattat ccgaagcgta ttctcttttt taccttgcat ggaaaaaagc ggtggggtaa
     5401 tgacaaactg ggtatctttc tggtcacccg cattttctat ccatgactga atgagataga
     5461 cactggcagg atcattattc gtgacaggca ataaaacctg tttctggttt gccggataaa
     5521 ttacccgcgt cgcaccaagt gcgacagctg cgttggcaat ggtgctatgg caagcaaaga
     5581 gaaataaaag taacactgtc gccataaagg aaacagagta gggggtacgc gtagtttgca
     5641 tctgatgcat tctccatgtg ttaagaggat aagcggggaa accgttacat cagacaatcg
     5701 gtaaatattg ctaatacatt ggcgagtcgc cgggtttcca gacttaatgc gtttgtaata
     5761 aatgttggtt ctcttttgat aggaaaacct tgctaccaag taaatatttt aaataacagc
     5821 aagtttaact actgttgttt attgatcgtt tagatattat gtgatttttc ataccgctcc
     5881 aaaatacaaa ccatttttca ttaataatga gatgaacatt ggtgaatttc tcgggtgtgc
     5941 gtagccatgc cacacacacc ctgtttcaat ttcagatgac gcatagtcac cttaagagtg
     6001 aattatagat attgaacttt gaaggtcgca tcagcatttg cagtaccagc tactgactgc
     6061 ccgagagcaa tataacgagc ctggaacggc agtatattcg tgccatcaat caagtcagtt
     6121 ttagcgctaa aagtagcacc atcaagtact aatacctccc ctgtacggtc caaaatttgg
     6181 ataccgacat tttgggcaga gcctgccgct gaactctgca gcgctaatgt atcgtcatta
     6241 ctggtgacag tagtacccag gaatgcaaca gctgcattac tggaaacatt ggtatcacaa
     6301 tcattcagct tgatattgaa gccaacggcg gagctgaggt cacccgcttt agccaggcga
     6361 gaagaacgaa cctgacccag ctcaaccgtt tggttcattg attctgaatc aatcgcacaa
     6421 gcggcattta ccacttcacc tttaaaatga attacaccgc cattaacagt ggtcgttact
     6481 gattcatcac cctcggctgc gcttaccgca gcagacgaca tcgccaacac agaaacgaca
     6541 ataataccga catgtttgag tttcataatt ctccaaaatt tatatttaag tagctgaata
     6601 aagagagtta acaattaagt tattctgtta ttgcttataa aacaagaatc attcttgatt
     6661 ggatgttgcc ctgagaatat agtttccatg gttattacat ttcacgaaga atgataatat
     6721 ctttaaatta caaggacacc tattcacaac aattttattg ctgcacttgt tgtagagagt
     6781 atttgtaaaa acattttatg tcgctaaata acatgacgat ttcattatgc atgttattta
     6841 taaacagcga ctaaacagaa tattattgcg aacaagggaa gtgtcaggaa aggtcaagag
     6901 gtactaatag tttatatggc tataaacatt agctatggtt aatgtttgcc tggtgaaact
     6961 aactgaatcc catgaataat gcagtaatta gtagtgcttt catatctgat acctgtttta
     7021 aacgatatat ttggaagttg acgaatatcg gaaatagctt cctccatcag ctgtagtcac
     7081 tgttctctgt atttcacatt gcatatcaac acgatatgct gagattagct aacttgagat
     7141 taaagataat tacacggcgc tatgaattat attcagaagc gtgagggata tagtgccatc
     7201 aaagcgctgg ctgctgtaaa caacgcaatt atccagctca tggtctatgg tgtgccatca
     7261 ctgaacagag gttgattttt ctaccgaaac gggagggaag tcagaaatca caacgtattg
     7321 atttatctgt gtgtggatgt gaatggtgaa gtaaaggacc ttcataatca atttaacata
     7381 atatacatta tgcgcaccaa tataaaccaa gggcgaatcc agtcgttggc ggttcatgat
     7441 tgttctgctc attaacaacg accaaaaccc catatcttac ttaataccgt attctcggct
     7501 taaccgatcg tgcaacctca acacattggt ttcaactgcc gtcaccacgt tctccggaaa
     7561 atctgtcggt aatgaagtct tcacgttatc cagtgctgcc ggaatcattc tggcaaagtc
     7621 actcaggatt tcatgcatct gcacttccgg gaatttcagc acctttgctg tcgccagaaa
     7681 atgtcgcgga taaattttat cgattgccgt ttttttgcct ttggatgcgt taagccccat
     7741 tgccagtttg agatcgctga tgtgtattcc cgtaccgcca aggaccggaa atgccgaaat
     7801 gatgtcgtaa aatggtgtga gccgataact gccgccagcc tgaataaata cggagaagtt
     7861 ttttgcatgg ccatccgttg cgccaatcaa ccactggaag acctgaaact tcataaaatc
     7921 atagcgatct ttcagcgcct cgctggaccc catcaaaaaa gccataattt gcgcgatacc
     7981 ggggcctcca tctgattcat atttcaccga tgaaggtaaa ccgaatgtct ggcacatatc
     8041 ctcctgtggc aagcgaagta aaaccgttcg ctcagtattc caacgcctgt caaaacgttc
     8101 gaccgctaac gcgcgcaccc ttcccgcttt aatgatttct gcgtccggaa cattcaaccc
     8161 gagttctttc gccagcagca aacagtaata ctcattatca acgctttggc taagatcgag
     8221 cgtcgcattg ggctgtctga tttcgccaat cggcaatttg ataatgtgcg tcgttggcgt
     8281 tattcccttc ggaatgcacc agtcattgcc tattctgagc agcgcagtct tctcctgtgc
     8341 gccagcaacc gagatgcgaa agtcattttc ttctctaatc atgcctaacg ggatatctgc
     8401 tttataagcc gttaatactt cttcaagtct ggcttcagta agcttttccc atgccattat
     8461 cggacacgtt acggtttcat cttcggggat taacgtcacg gcaccaacgc tgtctcgccc
     8521 tatttctgac aataaatcaa acggttgtct ggatttagca tgataacgtt taacgatccg
     8581 gtcacgtaca atcgggctat cgggtaacag gttatcgaag aagttaaata cggcatcaga
     8641 ggtgatattc cccctctgca atggcagcga aagtgacaac ggtctggcat aacggctggc
     8701 taaccactca gctgcatact taaaggtgtg cgcgccgttg gctaacttcg ttaactcgcc
     8761 tacccgctgg ttgttcatcc aagtgactag tttaggcatt accactccag atcttgctgt
     8821 tctgttgctt ctggcgaggc atttttcgcg tcgcatagcg tcattgagag ttcaagcgac
     8881 tgtaaaatct taaaaaatgt cgtgagcgag gtattgtcag gattgttttc gaaattggaa
     8941 attgtcgcct gcttaatgcc gatttttttc gccaactcgc tctgcgtcca gccgttttgc
     9001 tggcgaacca gtttcattgc attcgccaat tgcgttgggc tatagatctt ctgaaagctc
     9061 atcatgtcat acgtccacag caaatttatc cgcttaaggg gatattatca gttttatcct
     9121 ttagtgagga taaagtcaat ctggaaacac atcttatccg ctctacggga taaacgctgc
     9181 gatatccgcg atcgcggata aaaaggagga tttaaaaaag cacatcctaa tgcggtggct
     9241 tctttgacta ccggaatctg taatcttaat gaccgggccg cgtaaaaaac gtctgttcaa
     9301 tggggtgatg ccgtgaggcg aatttatcag ttttatctac aattggggta acgcgctgac
     9361 gggagtaaaa aaatgtctga ctggaacccc tctttatatc tgcactttgc cgctgaacga
     9421 tcgcgtccgg cggtggagct gcttgccagg gtgccgctgg agaatatcga atacattgcc
     9481 gatcttggct gtggcccagg taacatcacc gcccttctac accaacgttg gcctgctgcc
     9541 aggataacgg gcatcgactc atctccggcg atgattgctg aagcgcgcag tgctttgcca
     9601 gactgcctgt ttgtggaagc agatatccgc aactggcaac cggaacaggc actcgatctg
     9661 atttttgcta atgcctcact gcaatggctg cccgaccact acgaattgtt tcctcatttg
     9721 gtttcgttac ttaattcgca tggtgtgttg gcaatacaga tgccagataa ctggctagag
     9781 ccaacccatg tgctcatgcg cgaagtcgcc tgggaacaaa attatccgga tcgcgggcgt
     9841 gagccgctgg ctggcgttca tgcttactac gatattctga gtgaagccgg atgtgaggtc
     9901 gatatctggc gaaccactta ctatcaccag atgccgtcgc accaggcgat tatcgattgg
     9961 gtgaccgcca ctggattacg tccgtggtta caggatctga ccgagagcga acagcagcat
    10021 tttcttacgc gctaccatca gatgctggaa gagcaatatc ccctccagga gaacggacag
    10081 atattgctgg catttccgcg tctgtttatt gttgcccgcc gtacggagta attatcacgt
    10141 cagctggtaa tggcgatcgg gaagaatttt cgctggaatt tctgcttcat cattcatctg
    10201 taacaggtca atttcaatag cgttgcagat ggcatccagc ggtaaatcat tgttttcagt
    10261 accgaaggga tcttccagtt cttccgccag acaatccagc gaaataaaag tgtaggaaat
    10321 cagcacagag ataaaaggcg tcatgtaatg caggtccacg accagcgcaa acggcaacat
    10381 gatacaaaac agatacacgg tgcgatgcaa aatcagggtg taggcaaagg gaattggcgt
    10441 ataggcaatg cgctcgcatc ctgccaggac cgctgaaata tcattaagcc gatcgttgag
    10501 gctaataaac aggatatctg aaagttgtcc attgcgtcgc tgaaccgcca accactcccc
    10561 cattattaac aagatgcggt tagctggaga gttagaagcc agtacacgct gaagatcttc
    10621 agtcttgaga taatgagcca gcacttctgc ctgtggctgt ttgcgtaatg tcatgcgtaa
    10681 acagtgggcg aagacgattt gcagccgggc aaactccctt acacttgccg aatccggtaa
    10741 tgtcgttttt acctcgcgca gtaacgaccg cgaggcaatc atcaactgcc cccaaagttt
    10801 tcgcgcttca acgtaacggg cgtaaccggc attattacga aaaccaagaa aaatggcgat
    10861 ggcgacaccg agaatgctga acggtgcgag ggtgaattta atgcccaaat gcgtgtacca
    10921 gggcagcatg aaaataacag cgatcgaaaa gagaaaattg agtagtaagc gcgaggatat
    10981 cttggataat actgaaccgt gccagacaaa aatacggcgc agccagtgtt gttgtggacg
    11041 aacaatcatg gttatcttca ggcgtggaaa agtcgcccta ttaaacgtga ttatgatcac
    11101 attctcaaga tactacttac aaattaccta caagattaca acattaacag gtgctgcatg
    11161 tggcacctgt taatgataaa ggcatataga atgttgtaac taatatagcg gaataagaaa
    11221 cccggtcgaa accgggttca gagtattagc acaacgggcg tacagcttcg cgcatccctt
    11281 tttcgagaat cgcatccagg tcattagcaa cctgctcgac cagaccaggc acttgcgtca
    11341 ggtcctgctc ccagtggtct ttttctgcca acacaatcgc taccagttcc tgggtcccga
    11401 taacacggtc acgatactgg ctccagagtt gctgataacg ttccagccag tgtgcatcgt
    11461 cctgtaccgg atatgtttct ccattacgca caccgcgata gaacgcaatc aatgccgcta
    11521 atgcgaaagt aaggcgcgcc ggaagtgtgc cgtttgcctt ctgccctgcc agcagctgcg
    11581 gcaggatgcg tgtgcggaac ttggtcatac cgttgagcgc gatagacagc agttgatgct
    11641 tgatgtacgg gttacggaaa cgtccggtga ctgcactggc gaaagactcc agctcatcgc
    11701 gtggcaaatc cagtaccgga ataatttctt cgtagatggc tttttcaacg aatgcgcaaa
    11761 tttcagcatc gttcatcgct tcacctacgg tatccagccc tgcctggaac gccaccggca
    11821 ccagcgcggt gtgcgcaccg ttgaggattg ccactttgcg ttctttatac ggtttaatat
    11881 cgtcaacgat cagcacgtta agcggatatt tgtccagacg aagttcagtc gctaaggatt
    11941 tcggcccctg aatcacaaac aggtaaaagt gttcagcggt gtcgaggaaa ccatcgtggt
    12001 agcccagttc ttcttccagt ttagccactt catcacgcgg ataaccggta acgatacggt
    12061 ccaccagcgt agaacagaag ctgttagcct gatccagcca ttgaataaat gcttcaggca
    12121 atgcccactc ttgcgcatag cgcagcacca gttcacgcaa cgcgtcgcca ttatagtcaa
    12181 tcaactcaca cgggatgatg atccaacctt tatccagcgc accgttgaaa tggctaaaac
    12241 gttcgaacag cagacgggtc agttttgccg gataacttac cgctggcgcg tcatcgaatt
    12301 tatcgcccgc atggtagctg atacccgctt cggtggtgtt agagaaaaca aagcgcattt
    12361 ccgggttgtg agccagtttc aggaattcat cgtattcact atagacgctg atttcacgat
    12421 taaccgagcg aatcagacgc gcgtcgctga ccgcttcacc cttctcattc aggccacgga
    12481 taatggtggt atacagacca tcctgcgtgc tcagtgacgg cgggaatgaa gtttcaatcg
    12541 gacgaacaac gaccacgcca gaattcagat cggtgtgctc attcaggaga tcgatttgcc
    12601 agtcaacaaa ggcgcgcagg aagttacctt caccaaactg aatgatacgt tctggatact
    12661 gtgcaccggg aaaatcgcga cgatttagtg ttttcacaat gggttccctt ctgattagtc
    12721 atacaacctg tttgaattgg tacgacaggt tagcaaactt taatacgtcg aacccctgtt
    12781 ttgatcaact cctgatgatt aatgagcagt tttatgagaa aagtgtggcg cggatcatgg
    12841 tttaatcgag gaaacaggcc ttttcttgga tcataaagtg gtagaacaca ttgcatttaa
    12901 ttcgctctga gtaaataaag atgtcagaca acttcctcac cgtaacgcat agtgctggta
    12961 cggttgcgcc catctttctt cgagcgatac agacacgtat cggcttcgac catcaattta
    13021 ttaaagtcat cggtcagcgt tcggtacgat gcgcaaccac taccgacgcc aatacttacc
    13081 gtgagataaa gcgttttttg ttgccaggtg aacggttgca gttcaacgcc tttacggatt
    13141 ttttccgcca ttagcaggcc atcgacagga ttcacagacg gcactgcaac agcaaattct
    13201 tcgccgccca ttcgcgccac cagcccctta tcaccgacaa tcttctgaat atgctgggca
    13261 aacacgctta acactttatc gccacattca tgtccatagt tatcgttaat gcttttgaaa
    13321 tagtcgatat caagcagcat gaccgtcaga tgttgtgtct gtttcagcga tggacttttc
    13381 agcgcctcat aaagaccgga ccgtgagtaa acctgggtca gaaaatcaaa atcggctcgc
    13441 agcgcaactt gcttcattag cgaattgatc gctgccacgc taaaggaaac cataattggg
    13501 catatcgcca tcgtggcaat accgagacgt gcggagaaca tttgcggaat ggagaacggc
    13561 gaaccgaccg agatatcaat caccgaattt gccaccagta cgacttccac agcgccggtg
    13621 acaaaggtca acagacatgt tacttgcggc gtatagcgca ctgcacacca gattaatgca
    13681 gggagcggaa acgccagact ccccgctccg ccaatgacta ccgaggcaat aaccgacaca
    13741 ataagcgcga tagcaggcat catctgctct gctttaaagc gcggcagcac tccaggaatt
    13801 gccaacgtca gcatacaagg cacgatcaac acgcccgttg agaattgctc actaaaccag
    13861 tcggcaagca aaggccagaa atccagagta tcaatactga ccgaaccaat cgccccgaca
    13921 atagcgcata ataatgcggc aagcagacag taattaaata accgtaaggc acttactggc
    13981 tcatacttat tttttcccag acgcttatcc cgcgcgacca gtaaggcgac ggtaacaata
    14041 aacatcatat tggagaaatt gatagccagt gaaaccagcc cccattcggt ggttatggca
    14101 tcataaacca gcatcgccac ataactgatc gcatagtaat gcagtcgatt aagccagaca
    14161 tagcgggcaa acacccccgc cattacgcca ttcagcggcc agaaaagaga aagttcgtga
    14221 accagccgta actctgcacc aataaaatag aacagcgtgg ttagcacaaa aatagcgatg
    14281 ctattacgta gcagatgacc ttcctggaac aaacggaaag ttgaaatggg ctgtacatgc
    14341 attaattatc tgtccataca attgcgggtg gcaattatct caacgcaata agtaaattct
    14401 tagaaaggat agcatgttcg ctgacaacgg cggcaactaa agatacctaa tgaatgccat
    14461 tttatcgatt tccgtaatta tcatggctga ttcatctgta taaccagcca gtgatagatt
    14521 accgtcacaa tataacgttg ttgctcctca cttaacgctt ccccctgagg aatgttatgc
    14581 cacttagcca gacaaccgcg acaacaggtc gcggtggcgt gttgagcgat aaaaaccgga
    14641 tgcccgcgca tgggggtttg cttaccgtcg ttagccggta atgccggagc aagacgttta
    14701 gcgacaaaat ctgccgcatg ttgttcaatg actggcgcgc ctttctccag acaatactga
    14761 cgctctttca cacccaaacg aaagcgagag cgaaattttg aacgggataa acgcgcgaag
    14821 agtggatcga gagactgcat taataaactg aacgccctaa ttgtttcgtc aattgttcaa
    14881 ggacggcaat gcccgcaagc gagttaccgg catcatccag ttccggactc cagacagcga
    14941 tggccatttc atgcggaaca atcgccacaa taccgccacc aacgccagat tttgccggta
    15001 gtcccacccg ccaggcaaac tcccccgcgt tctggtacat accgctggtc gccatcagcg
    15061 cgttaatttg ccgcgcctgc attggcgtca ccacaggttc atcaatatga atagctttcc
    15121 cctgattcgc cagaaagaca aacgtccggg ccagctctac acagctcatt ttcagagcgc
    15181 agtaatgaaa gtagttttgc agaacggttg tcacgtcatg atggaaattg ccaaacgact
    15241 tcatcagcca ggcgatagcc gcatttcgcg cggaatgttc aaattcggaa cgcgctacca
    15301 ccgtatcgta ggaaatatca gacacaccac ttaagccgcg cacgacttcc agcatacgtt
    15361 gccgaggtgc gcttaatcgc ccttgcaaca tatcgcagac caccagcgca ccggcattaa
    15421 taaacggatt acgcggaata ccctgctcca tttccagttg cactaaagaa ttgaatggtg
    15481 atccagacgg atctttgccg acgcgttgcc agatttcctc ttcggagtaa tgacgcatgg
    15541 cgacaacgag actcagcact ttggaaatag actgaatgga aaaacgttct tgcgcgtctc
    15601 cggcctgaaa aagctgtccg tcaacggtac agatagcaat ccccaatcgg gaaccgtcta
    15661 ccgtagccag cgccggaata taatccgcga ctttaccctg accaatgagc ggccgcactt
    15721 gccgcaagat gttttctaaa attgcattat ccatggcgac tgccactttc tactcctgga
    15781 ccgcaggtct gaaaagacct gcgagtatat cagagctgaa tatatagcgt cagacccggt
    15841 ctttccacac cgtctggata ttacagaatt cgtgtaagcc gaaatgggaa agctcacgac
    15901 caaagccact cttcttcacg ccaccaaagg cgactcgcgc atcgctggca caataaccat
    15961 tgataaacac cccaccgcat tccagacgtg ccgccatctg tctggcctgt gtttcgtcgg
    16021 tggtgaaaat ggtcgctgaa aggccgaact cactatcatt agccagttcc agcgcatgtt
    16081 ctgcatcttt cgcaatggtg attgccgcaa cggggccaaa catttcttcc cgaaacgcgg
    16141 tcatttctgg ggtaacattc gccagaaccg ttggcggata gtagttacct gccccagcca
    16201 tcttttcccc gcccagtaac aaacgcgcac cctgcgccag tgttttttcc acctgatgat
    16261 gcagctcatc acgtaaatca aaacgagcca ttggtccgag agcgttgtct tcatcacggg
    16321 gatcgcccat tttcaaggct gccgcagctg ccacaaaacg ttcggtaaat gccgaagcaa
    16381 ttccctcttc gatgataaag cgttttgccg ctgcacaaac ctgtccggta ttctgataac
    16441 gtccggctac cgccgctttc accgccagtt ccagatcggc atcgttaagc acaataaacg
    16501 gatccgaacc acccagttcc agtacgcatt ttttcagtgc cgctccagcc tgtgcgccaa
    16561 tagccgctcc agcacgaaca cttccggtca ctgtgacagc agcaatgcgc gaatctttaa
    16621 tcatctgact gacaccgtcg ttgtcggcat tcagccagcc atatacgcct tgtgggatac
    16681 ccgcatcttt aaacacctgg gcaacgagct gtgcacagcc catcacattc ggcgcatgtt
    16741 taagtaagta gccgttacca gcaagaatga tgggaacagc gccacgcatc acctgccata
    16801 acggaaaatt ccacggcata atcgccagaa tcgtccccaa cggtcgatac tcaataaccg
    16861 cctgctgatt ttccaccagc gtaggttctg ccttcagcat tgccggacca tgttctgcat
    16921 accagtcaca caaattcgcc gatttcgcca cttcagcgcg cgcctggttg attggtttgc
    16981 ccatttcacg ggtgatcatt tgcgccattt cttcgctacg ggcgcgcaga gccttaccga
    17041 tatcacgcag tttttcagca cgataatcta tatttgtctc gcgccagtcg cgaaagcctg
    17101 ctgccgccag ctgaagtgcg ttttcgatat cgtcaacacc agcccacggc agcacagaaa
    17161 gttgttcacc ggtggcagga tttatcgaaa ttgcatgagt tgccggagta atggtcatcg
    17221 gggtatctcc tttatgagtc atggtatgaa gatacgcaga tttactcttg ctttaaaatg
    17281 aataatatta agccacttat tcacgaatcg agaatgccat ggatctgacc caactggaga
    17341 tgttcaacgc ggttgccgaa gctggcagca ttacccaggc tgcagcaaaa gtgcatcgcg
    17401 tgccgtcgaa tctcactacc cgtctacgtc agctggaaac agaactgggg gttgatctgt
    17461 ttattcgcga gaatcagcgt ttacgtctct cgcctgccgg gcataacttt ttacgctata
    17521 gccaacaaat tctcgcatta gtggatgaag cgcggagcgt tgtcgctggc gatgagccgc
    17581 aaggtttatt ttctctggga tcgctggaaa gcaccgctgc agtgcgcatt ccggccacgc
    17641 tggcggaatt taaccgtcgt tatcccaaaa ttcagttttc actttccacc ggcccttccg
    17701 gcactatgct ggaaggtgtg ctggagggaa aactgaatgc ggcgtttatt gatggaccca
    17761 ttaaccatac tgccatcgac gggataccgg tataccgcga ggaactgatg atcgtcacgc
    17821 cacaaggaca tgcgccagta acccgtgcca gtcaggtgaa tggcagtaac atttatgcct
    17881 tccgcgccaa ttgttcgtat cgtcgccact tcgaaagctg gtttcatgct gacggtgccg
    17941 ctccgggaac tattcacgag atggagtctt atcacgggat gttggcctgt gtggtcgcag
    18001 gagcaggcat tgcgcttatt ccacgctcta tgctggaaag tatgccgggg catcaccagg
    18061 ttgaatcgtg gccgttagct gagcaatggc gttggttaac aacctggctg gtctggcgtc
    18121 gtggtgcgaa aacgcgtccg cttgaggcat ttattcaact gctggatgcg cctgactcgg
    18181 caaaacaggg ttaccaatga gctatttttg atagttcatg cggctaatat gctctatata
    18241 gtgatgttcc aatgacttat gactatatgg ggcaaatatg gttacgccag taagcatcag
    18301 caattacata tctcttcctg atgattttcc cgttcgtaat attgcacctc aagtaaaaga
    18361 agaacaggcc cccttcctga tcgtcattaa aatgtgatgt taacaactct ctgatgcgtg
    18421 acagaacaac cgtcagagag atggaaatgc gatccagatc acaaatgcat tgtattcaca
    18481 tcattaaccg ttttaagatc atttcatcac tttttcgcaa ctcacccgat aatctgttat
    18541 gacaacaaac actgtttccc gcaaagtagc gtggctacgg gtcgttacgc tggcagtcgc
    18601 cgcctttatc ttcaatacca ccgaatttgt ccctgttggc ctgctctctg acattgcgca
    18661 tagttttcac atgcaaaccg ctcaggtcgg catcatgttg acaatttatg catgggtagt
    18721 ggcgctaatg tcattgcctt ttatgttaat gaccagccag gttgaacgcc gcaaattact
    18781 gatctgcctg tttgtggtgt ttattgccag ccacgtactg tcgtttttat cgtggagttt
    18841 taccgttctg gtgatcagtc gcattggtgt ggcttttgca catgcgattt tctggtcgat
    18901 tacggcgtct ctggcgatcc gtatggctcc ggccgggaag cgagcacagg cattgagttt
    18961 aattgccacc ggtacagcac tggcaatggt attaggttta cctctcgggc gcattgtggg
    19021 gcagtatttt ggctggcgaa tgaccttctt cgcgattggt atcggggcgc ttcttaccct
    19081 tttgtgcctg attaagttac ttcccttgct gcccagtgag cattccggtt cattgaaaag
    19141 cctcccgcta ttgttccgcc gcccggcatt gatgagcatt tatttgttaa ctgtggtggt
    19201 tgtcaccgcc cattacacgg catacagcta tatcgagcct tttgtacaaa acattgcggg
    19261 attcagcgcc aactttgcca cggcattact gttattactc ggtggtgcgg gcattattgg
    19321 cagcgtgatt ttcggtaaac tgggtaatca gtatgcgtct gcgttggtga gtacagcgat
    19381 tgcgctattg ctggtgtgcc tggcactgct gctacctgcg gcgaacagtg aaatacacct
    19441 cggggtgctg agtattttct gggggatcgc gatgatgatc atcgggcttg gtatgcaggt
    19501 taaagtgctg gcgctggcac cagatgccac cgacgtcgcg atggcgctat tctccgggat
    19561 atttaatatt ggaatcggcg cgggtgcgtt ggtaggtaat caggtgagtc tgcactggtc
    19621 aatgtcgatg attggttatg tgggcgcggt gcctgctttt gctgcgttaa tatggtcaat
    19681 catcattttt cgccgctggc cagtgacact cgaagaacag acgcaatagt tgaaaggccc
    19741 attcgggcct tttttaatga tacgttttaa tgatttccag gatgccgtta ataataaact
    19801 gcacgcccat acataccagc aggaatccca tcagacggga gatcgcttca ataccaccct
    19861 tgcccaccag ccgcataatt gcgccagagc tgcgtagact tccccacaaa ataaccgcca
    19921 ccaggaaaaa gatcagcggc ggcgcaacca tcagtaccca atcagcgaag gttgaactct
    19981 gacgcactgt ggaggccgag ctaataatca tcgcaatggt tcccggaccg gcggtacttg
    20041 gcattgccag tggtacaaaa gcaatattgg cactgggttc atcttccagc tcttccgact
    20101 tgcttttcac ttccggtgaa tcaatcgctt tctgttgcgg aaagagcatc cgaaaaccga
    20161 taaacgcgac gatcaaaccg cctgcaattc gcagaccggg aatcgaaatg ccaaatgtat
    20221 ccatcaccag ttgcccggcg taatacgcca ccatcatgat ggcaaatacg tacaccgagg
    20281 ccatcaacga ctgacgatta cgttcggcac tgttcatgtt gcctgccagg ccaagaaata
    20341 acgcgacagt tgttaatggg ttagctaacg gcagtaacac caccagcccc aggcctattg
    20401 ctttaaacaa atctaacatt ggtggttgtt atcctgtgta tctggtttat cagcgaaaag
    20461 tataaggggt aaacaaggat aaagtgtcac tctttagcta accttgcatc gcattgacca
    20521 aaacttgaac cgatttagca aaacgtggca tcggtcaatt cattcatttg acttatactt
    20581 gcctgggcaa tattatcccc tgcaactaat tacttgccag ggcaactaat gtgaaaagta
    20641 ccagcgatct gttcaatgaa attattccat tgggtcgttt aatccatatg gttaatcaga
    20701 agaaagatcg cctgcttaac gagtatctgt ctccgctgga tattaccgcg gcacagttta
    20761 aggtgctctg ctctatccgc tgcgcggcgt gtattactcc ggttgaactg aaaaaagtgt
    20821 tgtcggtcga cctgggggca ctgacccgta tgctggatcg cctggtctgt aaaggctggg
    20881 tggaaaggtt gccgaacccg aatgataagc gcggcgtact ggtaaaactt accaccagcg
    20941 gcgcggcaat atgtgaacaa tgccatcaat tagttggcca ggacctgcat caagaattaa
    21001 caaaaaacct gacggcggac gaagtggcaa cacttgagca tttgcttaag aaagtcctgc
    21061 cgtaaacgaa aaaagaggta tgacgatgtc cagacgcaat actgacgcta ttaccattca
    21121 tagcattttg gactggatcg aggacaacct ggaatcgcca ctgtcactgg agaaagtgtc
    21181 agagcgttcg ggttactcca aatggcacct gcaacggatg tttaaaaaag aaaccggtca
    21241 ttcattaggc caatacatcc gtagccgtaa gatgacggaa atcgcgcaaa agctgaagga
    21301 aagtaacgag ccgatactct atctggcaga acgatatggc ttcgagtccc aacaaactct
    21361 gacccgaacc ttcaaaaatt actttgatgt tccgccgcat aaataccgga tgaccaatat
    21421 gcagggtgaa tcgcgctttt tacatccatt aaatcattac aacaactagt tgataacgtg
    21481 acaacgtcac tgaggcaatc atgaaaccac ttttatccgc aatagcaact gcgcttattc
    21541 tcttttctgc gcagggcgtt gcggaacaaa ccacgcagcc ggttgttact tcctgtggca
    21601 atgtcgtggt tgttccccca tcgcaggaac aaccaccgtt tgatttaaat cacatgggta
    21661 ctggcagtga taagtcggat gcgctcggcg tgccctatta taatcaacac gctatgtagt
    21721 ttgttctggc cccgacatct cggggcttat taacttccca cttttaccgc tttacgccac
    21781 cgcaagccaa atacattgat atacagcccg gtcataatga gcaccgcacc gaaaaattgc
    21841 agacccgtta agcgttcatc cagcaatagt gccgcacttg ccagtccaac tacaggcacc
    21901 agtaacgata acggtgcaac ccgccaggtt tcatagcgtc caagcagtgt tccccagatc
    21961 ccataaccaa caattgtcgc tacaaatgcc agatacatca gagacaagat ggtggtcata
    22021 tcgatagtaa ccagactgtg aatcatggtt gcggaaccat cgagaatcag cgaggcagca
    22081 aagaagggaa tgattgggat taatgcgctc cagattacca gcgacatcac cgccggacgc
    22141 gttgcgtgcg acatgatctt tttattgaag atgttgccac acgcccaact aaatgctgcc
    22201 gccagggtca acataaagcc gagcatcgcc acatgctgac cgttcagact atcttcgatt
    22261 aacaccagta cgccaaaaat cgctaaggcg atccccgtca attgtttgcc atgcagtcgc
    22321 tcaccgaaag taaacgcgcc aagcacgata gtaaaaaacg cctgtgcctg taacaccagc
    22381 gaagccagtc cagcaggcat accaaagtta atggcgcaga acagaaaagc aaactgcgca
    22441 aaactgatgg ttaatccata ccccagcagc aaattcagtg gtactttcgg tcgtgcgaca
    22501 aaaaagatgg ccgggaaagc aaccagcata aagcgcaaac cggccagcat cagcggtggc
    22561 atgttatgaa gccccacttt gatgaccaca aaatttagcc cccatacaac cactaccagt
    22621 agcgccaaca ccccatcttt tcgcgacatt ctaccgcctc tgaatttcat cttttgtaag
    22681 caatcaactt agctgaattt acttttcttt aacagttgat tcgttagtca ccgtttacga
    22741 cggcattaat gcgcaaataa gtcgctatac ttcggatttt tgccatgcta ttcctttaca
    22801 tctctaaaac aaaacataac gaaacgcact gccggacaga caaatgaact tatccctacg
    22861 acgctctacc agcgcccttc ttgcctcgtc gttgttatta accatcggac gcggcgctac
    22921 gctgccgttt atgaccattt acttgagtcg ccagtacagc ctgagtgtcg atctaatcgg
    22981 ttatgcgatg acaattgcgc tcactattgg cgtcgttttt agcctcggtt ttggtatcct
    23041 ggcggataag ttcgacaaga aacgctatat gttactggca attaccgcct tcgctagcgg
    23101 ttttattgcc attcctttag tgaataacgt gacgctggtg gtgctctttt ttgcccttat
    23161 taactgcgcc tactccgttt ttgctaccgt gctgaaagcc tggtttgccg acaatctttc
    23221 gtccaccagc aaaacgaaga ttttctcaat caactacacc atgctcaaca ttggctggac
    23281 catcggtccg ccactcggca cgctgttggt gatgcagagc atcaatctgc ccttctggct
    23341 ggcagctatc tgttccgcgt ttcccatgct tttcattcaa atttgggtaa agcgcagcga
    23401 gaaaatcatc gccacggaaa caggcagtgt ctggtcgccg aaagttttat tacaagataa
    23461 agcactgttg tggtttacct gctctggctt tctggcttct tttgttagcg gcgcatttgc
    23521 ttcatgcatt tcacaatatg tgatggtgat tgctgatggt gattttgccg aaaaggtggt
    23581 cgcggttgtt cttccggtga atgctgccat ggtagttacg ttgcaatatt ccgtaggccg
    23641 ccgccttaac ccggctaaca tccgcgcgct gatgacagca ggcaccttct gtttcgtcat
    23701 cgggctggtc ggttttattt tttccggcaa cagcctgcta atgtggggta tgtcagctgc
    23761 ggtatttact gtcggtgaaa tcatttatgc gccgggcgag tatatgttga ttgaccatat
    23821 tgcgccgcca ggaatgaaag ccagctattt ttccgcccag tctttaggct ggcttggtgc
    23881 tgcgattaac ccattagtga gtggcatagt acttaccagt ctgccgcctt tctcgctgtt
    23941 tatcatctta gcgttggtga tcgttgttgc gtgggtgctg atgttaaaag gaattcgtgc
    24001 aagaccgtgg gggcagcccg cgctttgttg atttaagtcg aacacaataa gaatttaatt
    24061 cagccttcgt ttaggttacc tctgctaata tctttctcat tgagatgaaa attaaggtaa
    24121 gcgaggaaac acaccacacc ataaacggag gcaaataatg ctgggtaata tgaatgtttt
    24181 tatggccgta ctgggaataa ttttattttc tgggtttctg gccgcgtatt tcagccacaa
    24241 atgggatgac taatgaacgg agataatccc tcacctaacc ggccccttgt tacagttgtg
    24301 tacaaggggc ctgattttta tgacggcgaa aaaaaaccgc cagtaaaccg gcggtgaatg
    24361 cttgcatgga tagatttgtg ttttgctttt acgctaacag gcattttcct gcactgataa
    24421 cggatcgttg acacagtagc atcagttttc tcaatgaatg ttaaacggag cttaaactcg
    24481 gttaatcaca ttttgttcgt caataaacat gcagcgattc cttccggttt gcttaccctc
    24541 atacattgcc ctgtccgctc ttccaatgac cacatccaga ggctcttcag gaaatgcacg
    24601 actcacacca gcagtcacgg taatgttgat atgcccttca gaatgtgtga tggcatggtt
    24661 atcgactaac tggcaaattc tgacacctgc acgacatgct tcttcatcat tagtcgcttt
    24721 gacaataatg ataaattctt cgcccccgta gcgataaacc gtttcgtaat cgcgcgtcca
    24781 actggctaag taagttgcga gggtgcgtaa tactacatcg ccgattaaat gcccgtaggt
    24841 atcattaacc aatttaaatc ggtctatatc caacaacatt aaataaagat tcagaggttc
    24901 agcattgcgt aactgatgat cgaaggattc atcaagaacc cgacgacccg gcaatcccgt
    24961 cagaacatcc atattgctac ggaccgtaag caaataaatt ttgtaatcgg ttaatgccgc
    25021 agtaaaagaa agcaaccctt cctgaaaagc gtcgaaatgc gcgtcctgcc agtgattttc
    25081 aacaatagcc agcattaatt cccgaccaca gttatgcata tgttgatggg cagaatccat
    25141 tagccgaacg taaggtaatt catcgttatc gagtggcccc agatgatcaa tccaccgacc
    25201 aaactggcac agtccataag aatggttatc cgttatttct ggcttactgg catctctcgc
    25261 gaccacgctg tgaaacatac ttaccagcca ctggtagtgg gcatcgatag ccttattgag
    25321 atttaacaag atggcatcaa tttccgttgt cttcttgatc attgccactc ctttttcaca
    25381 gttccttgtg cgcgctattc taacgagaga aaagcaaaat tacgtcaata ttttcataga
    25441 aatccgaagt tatgagcatc tctgagataa cattgtgatt taaaacaaaa tcagcagata
    25501 aaaaagtgtt taattctata aattaactct gcattatcgc aattaaaagg atgacaaata
    25561 gcataaccca ataccctaat ggcccagtag ttcaggccat caggctaatt tatttttatt
    25621 tctgcaaatg agtgacccga acgacggccg gcgcgctttt cttatccaga ctgccgctaa
    25681 tgttgatcat ctggtccggc tgaatttgaa aattattata acggaagagt atacaaaaaa
    25741 agtaattttg ctggcgactg cgaaacggca ttcgcattag cggtgaagtt tgccctcgcc
    25801 cagcggctgc aattactgct ataacgaggc tggtctggcg ataaatccag gccagccatt
    25861 ggtggtgttt atacgttcaa gccacgatgt tgcaacatcg gcataatctg aggtgcctta
    25921 ccgcgccatt gtcggtacag gcgttccaga tcttcgctgt tacctctgga aagaatcgcc
    25981 tcgcgaaaac gccgcccatt ttcacgcgtt aatccgccct gctcaacaaa ccactggtaa
    26041 ccatcatcgg ccaacatttg cgtccacaga taagcgtaat aacctgcggc atatccgcca
    26101 ccaaaaatat gggcgaaata actgctgcga tagcgtggcg gtatagcagg aagatccata
    26161 ttttccgcca ccagcgcccg caattcgaaa tcatcgacat cctgcattgc ttcgttttct
    26221 tccaggcaat gccagcgcat atcgagaagt gcggcgctaa gcagttcgct catctcatac
    26281 cctttattga acaggctggc attacgcatt ttctgttgaa gttcgtcagg cattgcggtc
    26341 ccgctctgat aatgccgggc gtagcgagcg aatacctgcg gatgtgttgc ccagtgttcg
    26401 ttgatttgcg acggaaattc gacaaaatca cgcggcgtgt tggtgccgga aagcgtggca
    26461 taacgctggc gggcaaaaag gccgtgcagc gtatgaccaa attcatggaa taaggttatt
    26521 acatcatccc agagtaacaa cgcaggctca ccggcagcgg gtttctgata attgcagacg
    26581 ttataaatta ccgggtgcgt ttcattcagc gttgattgct caacaaaatt gcccatccat
    26641 gcgccgccgc tttttgaatc acgggcgaag aaatcaccgt aaaataacgc cagccccacg
    26701 ccattatgat caaaaatttc ccacacacga acgtcaggat ggtagacagg aatatcaaaa
    26761 cgttcgacaa acttaatacc gaagagctga ttcgcagtcc agaatacgcc ttcattcaac
    26821 accgtgttta attcaaaata tggcttgagc tgcgcttcat cgagatcgaa tttctcacgt
    26881 cttacctgct cggcataaaa tgcccagtcc cacggctgcg cgctaaaccc gccctgctgc
    26941 ttatcgataa ccgcctgtat ggaggctaat tcatcgctcg cacgttgacg cgccgctgga
    27001 acaatttccc gcataaagtt gagcgctgct tctggcgttt ttgccatctg atcggcgatt
    27061 ttccatgcgg cataatgagg aaaaccaagc agtttcgcct gctgcgcgcg gatctccacc
    27121 agacgttgaa tgatagcgcg ggtatcattg gcatcatttt tttccgctcg cctccagccc
    27181 gcagtaaaca gtttttcacg cgtcgcgcga tcgcgcagtt cagcaagcgc tggttgctgg
    27241 gtggtattca gcagcggaat cagccagttg ttatccagac ctttctcgcg agccgcctct
    27301 gccgccagcg caatctcttg ttcactcatt cctgccagct gcgcgatatc gttcacaacc
    27361 agaccgccgg atttatttgc tgccagtaac cgctggttaa actggctggt cagggtcgca
    27421 gcttctgtat tcagtacttt taattttgct ttatcagctt gctcaagttt ggctccggca
    27481 aggacaaaac gttgatgaat cacctccacc aggcggatgg attcactatc aagccccagg
    27541 gattcacggc gttgccagac agcatctacc cgcgcgaata attccccgtt cagatagata
    27601 tcattcgcaa gttccgccag ttcagcggaa aactgttcat caagacgctg taattcatca
    27661 ttggtatgcg ccgcagtcat cgcaaaaaag acgctggtaa cgcgggtaag taattctccg
    27721 ctttgttcca gtgccagaat agtattgttg aaatcaggtg tttgcgggtt aagcgcgatg
    27781 gcagcaattt ctgcccgctt ttgctgcatt ccctcatcga atgccgggcg atagtgatga
    27841 ttggcaattt gatcaaaatg gggagccaga tacggcagtg tgctttgcac aaggaaagga
    27901 ttcattgttg tcattttctt ctcctgaacg cgaggtgttc catagcgtag gcttactgat
    27961 aacggagtgc aatcttgcaa accagtatta cccgctctta agcatcacgt gctatgttat
    28021 tgacacacaa aatcgttgag gaacagtgag atgatcgttt tagtaactgg agcaacggca
    28081 ggttttggtg aatgcattac tcgtcgtttt attcaacaag ggcataaagt tatcgccact
    28141 ggtcgtcgcc aggagcggtt gcaggagtta aaagacgaac tgggagataa tctgtatatc
    28201 gcccaactgg acgttcgcaa ccgcgccgct attgaagaga tgctggcatc gctccctgcc
    28261 gagtggagca atattgatat cctggtaaac aatgccggcc tggcgttggg catggagcct
    28321 gctcataaag ccagcattga agactgggaa acgatgattg ataccaacaa caaaggcctg
    28381 gtatatatga cgcgcgccgt cttaccgggt atggttgaac gtaatcatgg tcatattatt
    28441 aacattggct caacggcagg tagctggccg tatgccggtg gtaacgttta cggtgcgacg
    28501 aaagcgtttg ttcgtcaatt tagcctgaat ctgcgtacgg acctgcatgg tacggcggtg
    28561 cgcgtcaccg acatcgaacc gggtctggtg ggtggcaccg agttttccaa tgtccgcttt
    28621 aaaggcgatg acggtaaagc ggaaaaaacc tatcaaaata ccgttgcatt gacgccagaa
    28681 gatgtcagcg aagccgtctg gtgggtgtca acgctgcctg ctcacgtcaa tatcaataca
    28741 ctggaaatga tgccggttac ccaaagctat gccggactga atgtccaccg tcagtaattt
    28801 ttatacccgg cgtaactgcc gggttattgc ttgtcacaaa aaagtggtag actcatgcag
    28861 ttaactcact cacaagcaag aacgaatgac cgtcgaaacg caacttaatc ccacacagcc
    28921 tgtcaatcag cagatttatc gtattcttcg ccgcgacatt gtccattgcc tgattgcacc
    28981 aggcacaccg ttgtcggaaa aagaagtttc tgttcgtttc aatgtgtcac gccagccggt
    29041 tcgtgaagcc tttattaaac tggcggaaaa cggtctgatt caaattcgtc cgcagcgtgg
    29101 cagctacgtc aacaaaattt ccatggccca ggtgcgcaac ggcagtttta tccgtcaggc
    29161 cattgagtgc gcggtggcgc gtcgggcggc gagcatgatt accgaaagcc agtgctacca
    29221 actggaacaa aatcttcacc agcaacgcat tgccattgag cgcaagcaac tggatgattt
    29281 ttttgaactt gatgacaact tccatcaact cctgacgcag attgccgact gtcaactggc
    29341 gtgggatacc attgagaacc tgaaagcgac cgttgatcgc gtgcgctata tgagcttcga
    29401 ccacgtttct ccaccagaaa tgctgttacg ccagcatctt gatattttct ctgccctgca
    29461 aaaacgtgat ggcgatgcgg tagaacgtgc aatgacgcaa catttgcagg aaatcagcga
    29521 atccgtgcgc cagatccgcc aggaaaacag cgactggttt agcgaagagt aattcatttc
    29581 ctctcatccc atccggggtg agagtctttc cccccgactt atggctcatg catgcatcaa
    29641 aaaagatgtg agcttgatca aaaacaaaaa atatttcact cgacaggagt atttatattg
    29701 cgcccgttac gtgggcttcg actgtaaatc agaaaggaga aaacacctat gacgacctac
    29761 gatcgtaacc gtaacgcaat caccactggc agccgtgtta tggttagcgg caccggtcac
    29821 actggcaaga tcctgtcgat tgatactgaa ggtctgaccg ctgagcaaat ccgccgcgga
    29881 aaaaccgtag ttgttgaagg ttgtgaagag aaactggcac cactggacct gattcgtctc
    29941 ggcatgaact aagcgtgtga atgccgccga tggcggcatt gcttttttta cttcacggaa
    30001 tatttcgcca ctgtcgcttt cgcgccatgc gctaataaag acaagtacgc ttccgtcact
    30061 ttagtcgtaa acaagctatt atctggcaaa tcatcaccaa atatcgcctt aatcgccaac
    30121 aatgactgca cgcgcgctgt cccttcagca ctactttgta ctgccttctg aataacaggt
    30181 aacagtgggt cactgatttc tatcggattt ccctgttcat caacaccacc gacataacgc
    30241 atccaacccg cgacgcccag cgccagcaga tcgaacttgc tgtcatgcgc cagatgccag
    30301 cgaacagaat ccaacatccg ctgtggcaat ttctggctgc catccatcgc aatctgccag
    30361 gttcgatgac gtaacgccgg gttgctatag cgttcaatta atcggttagc gtaatcttgc
    30421 aaatcaacgc cctgcacttt cagcgtcggc gcttgttcct gcaacattaa ggtatacgcc
    30481 gcatgacgat aatgttcatc ctccatgcag tcattaatgt gctgatatcc ggcaagatag
    30541 cccagatacg ccaggaatga atgactgcca ttgagcatgc gcaacttcat ctcttcataa
    30601 ggcagcacat cactaaccag ttcgactccc gctttttccc attccggacg tccggcaaca
    30661 aagttatctt ctattaccca ctggcggaaa ggttcacagg caacgcctgc cggatcgcgc
    30721 acaccggtaa gttgttcgat tttcgccagc gtatcctctg tcactgcggg cacaatacgg
    30781 tccaccattg ttgatgggaa agtcacgtta tcttcgatcc attgtgccag ttttacatca
    30841 atggcttgcg cataggaagt gacaacgtca cgcataacat gaccgttttc tggcatgttg
    30901 tcacatgaca tgacggtaaa tgcgggaagt cctgccgctt tacggcgagc cagcgcctca
    30961 acaatcaccc ctgttgcagt tttcggctgg tggggatttt gcacgtcggc aacgaccatc
    31021 gggtgatcga gcattaactg tccggtcgcc ggagagtgga aatacccttt ttcggtgatt
    31081 gtcagagaga caatcgcgat ttgcggttca cacatcgcag ccaacacggt ttctaagccg
    31141 tctatttgta cgtgtaaggc ttttttaacg acgccaacga cgcgagccgt ccacgcatca
    31201 gccgacattt ccgcaacggt ataaagatta tcttgctgtt gtaaatcggc aatttgctgt
    31261 tcgccgccga ttaagttgac ctcataatat ccccagtcac tgaaatgttc cgtagcaaga
    31321 atatcggcat acacgccctg atgcgcacgg tgaaatgcac caaagcctaa atgaacaatt
    31381 cttggggcca ggttattacg atcataaaca gggagcgtcg cttttgctga taacaaatga
    31441 tttcccataa caattcctta aaattaaata tagcaagcta catgtttttt tatatgaata
    31501 aaaatcccct ctccggtaag agaagggatt gaggatttac agacttctgg acggttgcgc
    31561 agctcttaca acatgtggtt gatcttctgc ggcgtcttgc agcgcactta aatcacggtc
    31621 tttcacttct ggcattttca gcgcagagat taaaccaatc acagaatatg ccatgatcat
    31681 aatggcgatc ggataccagg attccgtcat ggtgcagaaa atccccgcca ggataggacc
    31741 aaaaccggaa gcgataagac caccaatttc tttagaaata gccattcggg taaagcggtt
    31801 tttacagccg aacatttctg ccatggtaat gttttccaga gcaaataatc caagcaccgc
    31861 acagttatga atcacaatca gtgcaaccat aatggtgctc ggggcatagc ttttatctac
    31921 gatgatagaa agcattggcc atgccagcac aatcgcagag gtattcataa taatatacgg
    31981 gatccggcga ccaattttat cggataacca accaaggaac ggaatggtca taaagccgag
    32041 aatcgaactg atcatcaatg catctgttgg aattgctttg ttaaacaata acgtctgcac
    32101 taaatagcct gcaaggaaag tctgaattaa acctgagtta ccagcctgac caaaacgcag
    32161 ccctgttgcc agccagaagg atttgctctg gaacatgcta ccagcaggtg caggttttgc
    32221 tgtcggttgg ttgctgtcgt taaccttctc aaagaccggg ctttctttca gattcatacg
    32281 caaccagata gcaaagacca tcacgacaac gctcgccagg aaaggtatac gccatcccca
    32341 cgccagcagt tcctctttac tgagaatgaa gaacataaag gcccagattg ccgttgcgct
    32401 caaggttccg cagttagttc ccatagccac aaatgaggag ataattccgc gcttaccttt
    32461 tggcgcatat tccgccagca tcgtaccggc accggaaatt tccgcacctg cacccaaccc
    32521 ctgaataata cgcagcgtca ccagcaagat gggggcaaaa acaccaattt gtgcataagt
    32581 cggtaacaca ccaattaagg tggtacagat ccccatcatg gtgatggtaa taaagagcac
    32641 ttttttacgc cctattctgt cgcccatttt gccgaaaata aatgctccga caatacgtgc
    32701 cacataacct gcaccatagg ttcccattgc cagaattaac gccattgccg ttgatgattc
    32761 aggaaaaaat atttcatgaa acactaacgc tgcgccgagc gaatataact ggaaatccat
    32821 aaattcaagc gcagtgccca gccatcccga tactgctgct ttcaccaaat ccttagtgct
    32881 tctttcgtgt ttttctattg tcataatggt tatctctaaa aaagaggtaa gatgcgtact
    32941 acttattcgc cgttattggt attattcaga aaaagtgagt aagactttgc agcaatgttt
    33001 ttgatcctgt tcaaataaac taatggcatc cgcaacatgc tggaaatcaa acgtatgggt
    33061 aattagtttt tctggtttaa ttaacccttt acttaaccag tcgataacga ccgggaattt
    33121 atttgcattt aagcgtgaag agaaaataga gagttctttt ccggtaattc cttgctgaat
    33181 cacttcagac ggttcactgg agaagcccat caatacaata cgtgccgctg gagaagccag
    33241 cgttacggcc tctttcaaga ttgaaggatg acaagcggca tcgataacta atgtcggttg
    33301 gatgcctttt tcatcgaaaa tctcgccaag tggtgtctgg ctgttattaa tcgcccagtc
    33361 tgccccgctc tctttcgctt tttccagtcg ttcatcaatg cgatcggcaa caatcacatt
    33421 tttaacgtta tagacgcctt ttaatacctg aacgatcgtc aggccgattg gaccggcacc
    33481 gtaaaccaga acggtatcat tttcagtcgg ttgaccatga ccggtaacgt tagccgcaat
    33541 ggtaaaaggt tcgatcatca ccgcatattg atcggccact gcttcaggaa ttttccacgc
    33601 attttttgcc ggaaccacgg catattcact gaaaccaccg tcagcgtgca cacctaatac
    33661 agcaagtgtc gtacaaacgt tcggcttacc tatagagcac ggatagcaat gcccacagct
    33721 gaccaccgga tcgacagcaa cgcgttcacc gactctggcg ctttccacgc cttcacccac
    33781 tgcatcaatg acgccaaaga attcatgacc aatgacgcgc ggatatttcg caaaaggatt
    33841 atgcccacgg taaatatggc tatctgaacc acaaattccg gcaagtttca cttttactcg
    33901 tacttcaccc gctgacgggg tgggtatttc acgttcgata atcgacagtt gattcggttt
    33961 ttcaattaaa atgcttttca ttaccttact ccttaccagt tccacagcgt gccatcttcc
    34021 agacgtgcga ctggcagata agcaggttca tagggatatt tcgccgccag cttttcatcg
    34081 aattcgatgc caagacccgg tttttctccc ggatgcatat agccgttatc gaaagtccag
    34141 ttgtgcggga agacttcgag catttgttcg gaataaccca tgtattcctg gacaccgaaa
    34201 ttggggaccc acagatcaaa gtgcagcgcc gcagccatgc agactggtga caaatcggaa
    34261 ggaccgtgtg agccagtacg tacctgatac agcgaagcaa aatcggcaat ccgacgcata
    34321 ccggtaattc cgcctgcatg agtcagcgtg gtgcggatat aatcgatgag ttgctcttca
    34381 atcagttgtt tgcagtccca gatgctgttg aagacttcac ccaccgcgat gggtgtgacg
    34441 gtatgttggc gaatgagacg gaagcattcc tggttttccg caggcgtcgg gtcttccatc
    34501 cagaacatgc gataatcttc aatgctttta ccaaagcgcg ccgcttcaat aggcgttaag
    34561 cgatggtgca tgtcatgcag caaatgttca ttaaatccaa acttgttacg taccgcgtca
    34621 aacaatttcg gcatgaaatc gaggtatttc tccgtcgacc acagctgctc ttccggccac
    34681 tgtcctttgg ttgcgggttc ataagccaga cctttacctt tcgacatgcc gtaggtggtt
    34741 ttcataccag ggattccgca ctgcacgcgg atggctttga atcccagctc ctgatgacgg
    34801 gcataatcat ccagagcttc atcaatactg tgaccggtgg tatggcaata aaccatcacc
    34861 ccttcacgag acgcgccgcc gagtaactgg taaagcggca tgttggcagc tttggcttta
    34921 atatcccaca gcgccatatc aaccgctgaa atggccgaca tcgtaaccgg accgcgacgc
    34981 cagtaagcac ctttatagaa aaactgccag atatcttcga tacggtgtgc atcgcgacca
    35041 ataagctgcg gacaaaggtg atcctgcaaa taagaggcca cggaaagctc acgtccattt
    35101 agggtggcat ccccaaggcc cgtaataccg tcctcagtgg tgatttttaa tgtgacgaaa
    35161 ttacgccccg gacaggtaac aaaaacttca gcctttacga tcttcatgtt cgattccttg
    35221 catcgcttgt cgtgatgcat gaaatctacg caactgaact actaccatac aagtatgaag
    35281 atcaaaaaaa gccggagtga tcacaaaaaa aggcgtatat ttgcgccgtg aatggttgac
    35341 aaaagatgaa atagaatacc ttttgtcagc tgacacttcc tcgtatctta ttgataaaat
    35401 ggatttatgt tcctacgtgc gcccccagcc cgcaacaatg atcaacatgc cgcaaagcgc
    35461 aattaacgcc cccgtccagt cataaagagt cagtttcacg ccatccacaa cgcgcagcca
    35521 catcaacgcc gtgcaaacat aaacgccacc ataagccgcg taaacacgcc cactcgccgc
    35581 aggatgcaac gttaacaacc agacaaacag tgccagtgaa atccccgccg gaagcaacag
    35641 ccagatactg gcgtttcgtt ttaaccacaa ccagggcaga aagcatccaa taatttcaca
    35701 cagcgcagta gcaaaaaata gtaacgttgt tttaatcatc tttgtcactt attgacatca
    35761 tgtatagtta tagggcgaca taatatcatc aatataaaca ccctccttga acgttttgcg
    35821 ttcgcagtgg atggtgtaga atcagcttta atcattcata cagggaatga attatgaaaa
    35881 tcactctcag caaacgaatc ggcctgctcg cttttctgct gccttgcgca ctggtattga
    35941 gcacaactgt tcatgccgaa actaacaaac tggtgattga gtctggcgac agtgcacaaa
    36001 gccgccagcg cgccgctatg gaaaaagagc aatggaatga cacgcgtaat ctgcgccaga
    36061 aagtgaataa acgcactgaa aaagagtggg ataaagccga cgctgctttt gataaccgcg
    36121 ataaatgtga gcaaagcgcc aacatcaatg cctactggga gccaaatact ttgcgctgcc
    36181 tggaccgtcg aactggccgc gttattatcc cctaacctgt tattgattta aggaatgtaa
    36241 ggacacgtta tgccaagcgc ccacagtgtt aagctacgcc cgctggagcg tgaagattta
    36301 cgctatgtac atcaactcga caataacgcc agtgtgatgc gttactggtt tgaggaaccc
    36361 tacgaagcct ttgttgaact ctctgatctg tatgataagc atattcacga tcagagcgaa
    36421 cggcgctttg tggtggaatg tgacggcgaa aaagccggtc tggtggagct ggtggaaatt
    36481 aaccatgttc atcgccgcgc agaatttcag ataattatct ccccggagta tcaggggaaa
    36541 ggtctggcaa cccgtgccgc caaattagca atggactatg gcttcaccgt tctcaatctc
    36601 tataagctgt atctgatcgt tgataaagag aatgaaaaag cgattcacat ttaccgcaag
    36661 cttggcttta cggttgaagg tgaattgatg catgagttct ttattaatgg tcaatatcgt
    36721 aatgccattc gcatgtgtat attccagcat cagtatctgg ctgagcacaa aacaccgggt
    36781 cagactctcc tgaagccgac cgcgcaatag tattaataat aatcgatcgt atttttgatg
    36841 gtataaaccc gttcgacggc gggttttact ccttcatcaa caatgattag ctgacagtcc
    36901 accggattgg cgtgattgtc atattcacag ctctgtttta cattaccaac ccgttgatta
    36961 ttcagtaaag taacagcagt gtaatctaat tttttgatcg ggtccgttga tggcgtggcg
    37021 ctgacagata atgttttatc gttacttttc gtggttttac ccagcggata cccctgatca
    37081 tcatagcgat attccatctg catctgtttg ctgctggctt taatcacgaa accattatca
    37141 tcggtttccc aactcacccc ggcagaaggt aattctgcta gctggcattt tccctgcaaa
    37201 cgaactcttt tctccagcgt ctcggcatca cggtaataat tggcatccag taccagggca
    37261 accaaggtat tattttccag atccagtaat tcgagagaat caaaacagcc ttcttccgac
    37321 aaagtccccg aaacacgttt cgtcacttca ccttgctcat ccattaatgt ctgagtgaaa
    37381 tcttttacgg gaccacgcag cggatcaaaa tcgaattcat tagagaaact ggccatctcc
    37441 ggggtaaatg aaagtgttac ctctgtgcgg tcacatcctg tgagtaatat cgcgagtaag
    37501 catggcagta atttgtattt cacaacagtc acctgagagt agagatgatt ctcaatcata
    37561 gtagcaaata cagtacttta cacgttaaat gctatgctta aagaagttat cttcgcgtaa
    37621 ggagcttatg atgaaacact caacctactg tgccgcgctt ctgctcgccc tcgcctcacc
    37681 cacggtactc gccgcgccgg gatcctgtga gcgcatacag agcgatatat cacagcgcat
    37741 tatcaataat ggcgtacccg aaagcagctt cacgttaagt attgtaccca atgaccaggt
    37801 tgatcagcct gattcccagg tcgtcgggca ttgcgctaat gatacgcata aaattctcta
    37861 cacccgtacc accagcggta acgtctctgc tcccgcgcag tctacccagg atggcgcgcc
    37921 tgccgaaccg cagtaacaca ttatcgactg aacgccggat gcgacacatc cggcgatttg
    37981 aacattcaac ataaccccac cttattactc atacccttct attgatatgg attaataatt
    38041 attaacccca aatgggtaga ttccctcta
//
LOCUS       DAFGPF010000039        37746 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFGPF010000039 DAFGPF010000000
VERSION     DAFGPF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37746
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.039"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(2..1285)
                     /locus_tag="LSX49_002196"
     CDS             complement(2..1285)
                     /locus_tag="LSX49_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HBL7168598.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKILPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD"
     gene            complement(1398..3332)
                     /gene="yeaG"
                     /locus_tag="LSX49_002197"
     CDS             complement(1398..3332)
                     /gene="yeaG"
                     /locus_tag="LSX49_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HBL7168599.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            3768..4514
                     /gene="mipA"
                     /locus_tag="LSX49_002198"
     CDS             3768..4514
                     /gene="mipA"
                     /locus_tag="LSX49_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein MipA"
                     /protein_id="HBL7168600.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            4604..5458
                     /gene="yeaE"
                     /locus_tag="LSX49_002199"
     CDS             4604..5458
                     /gene="yeaE"
                     /locus_tag="LSX49_002199"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HBL7168601.1"
                     /translation="MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALIGLRENVFLVSKVYPWNAGGQKAINACEASLRRL
                     NTDYLDLYLLHWSGSFALEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATVAHVQQNAAVLEVELSSAELVMLDKAYPAPK
                     GKTALDMV"
     gene            complement(5509..6393)
                     /locus_tag="LSX49_002200"
     CDS             complement(5509..6393)
                     /locus_tag="LSX49_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HBL7168602.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGIPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHREDADGVALTFELTQSEETKKFWPHDFTLLAHFHVGKTCEIDLEAHGEFETT
                     SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKEDVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSVSMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(6477..7472)
                     /gene="gapA"
                     /locus_tag="LSX49_002201"
     CDS             complement(6477..7472)
                     /gene="gapA"
                     /locus_tag="LSX49_002201"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL7168603.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            7814..8227
                     /gene="msrB"
                     /locus_tag="LSX49_002202"
     CDS             7814..8227
                     /gene="msrB"
                     /locus_tag="LSX49_002202"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBL7168604.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            8269..8541
                     /locus_tag="LSX49_002203"
     CDS             8269..8541
                     /locus_tag="LSX49_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707337.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HBL7168605.1"
                     /translation="MNLDDIINSMTPEVYQRLSTAVELGKWPDGVTLTEEQKENCLQL
                     VMLWQARHNTEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            8911..9987
                     /locus_tag="LSX49_002204"
     CDS             8911..9987
                     /locus_tag="LSX49_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBL7168606.1"
                     /translation="MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMK
                     HYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGD
                     FLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
                     NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVTVRFPVA
                     KELGATAVVNGSTEDVVARCQQICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRV
                     GMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAIKVKPMITHRIGLSQ
                     WREGFDAMVDKTAIKVIMTYDFDE"
     gene            10014..11393
                     /locus_tag="LSX49_002205"
     CDS             10014..11393
                     /locus_tag="LSX49_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7168607.1"
                     /translation="MEQITKPHCGARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGL
                     ILAQLKALGWTDNSTTATFSAITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASM
                     VVGAFSPNMDFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSY
                     PLCSLIAMGLTPLISAEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEA
                     EKVMRSIEEGVIRQTGKPLPPVVIADDGKAPQAVPYSALLTGVLLKRVILGSCVLIAM
                     NVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGAPFGIFIAMLVMDKIPRKTMGVG
                     LLILIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSG
                     LANAVGRISGIAAPYAVAVLLSSYGVTGVFILLGAVSIIVAIAIATIGIETKGVSVES
                     LSIDAVANK"
     gene            11410..12453
                     /locus_tag="LSX49_002206"
     CDS             11410..12453
                     /locus_tag="LSX49_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HBL7168608.1"
                     /translation="MKNSKAMLQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVH
                     GFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCL
                     EGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
                     AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLTMAEQLGATVVI
                     NGAKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAI
                     NFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNN
                     KRDIIKGVIKISD"
     gene            12474..13310
                     /locus_tag="LSX49_002207"
     CDS             12474..13310
                     /locus_tag="LSX49_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL7168609.1"
                     /translation="MLADIRYWENDATNKHYAIAHFNVWNAEMLMGVIDAAEEAKSPV
                     IISFGTGFVGNTSFEDFSHMMVSMAQKATVPVITHWDHGRSMEIIHNAWTHGMNSLMR
                     DASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAE
                     FVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKT
                     AISLGIAKINIHTELCQAAMVAVKENQDQPFLHLEREVRKAIKERALDKIKLFGSDGK
                     AE"
     gene            13315..14262
                     /locus_tag="LSX49_002208"
     CDS             13315..14262
                     /locus_tag="LSX49_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HBL7168610.1"
                     /translation="MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDA
                     INEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLV
                     TEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGRALTEIFTQA
                     KTRQMIICADMIKPRLNETLNDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLA
                     CGVKTVVIKTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNL
                     RECARFANATAAISVLSIGATTGVKNRKLVEQLLEEYEG"
     gene            14272..15252
                     /gene="ydjG"
                     /locus_tag="LSX49_002209"
     CDS             14272..15252
                     /gene="ydjG"
                     /locus_tag="LSX49_002209"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent methylglyoxal reductase"
                     /protein_id="HBL7168611.1"
                     /translation="MKKIPLGTADITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILE
                     AHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGD
                     RQLYKNLSPESIREEVEASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNALKAE
                     GKIRAIGAANVDADHIREYLQHGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYS
                     PLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLAL
                     AWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALER"
     gene            15389..16147
                     /locus_tag="LSX49_002210"
     CDS             15389..16147
                     /locus_tag="LSX49_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7168612.1"
                     /translation="MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLE
                     DEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEKQLIARKALPFVDNKTTMAADSS
                     STVMELLKLLQDRSDLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEI
                     ISRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFV
                     QLADFSHINYIITDKSPGAEWIAFCKDNNIQLVW"
     gene            16265..17623
                     /locus_tag="LSX49_002211"
     CDS             16265..17623
                     /locus_tag="LSX49_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7168613.1"
                     /translation="MEQYDQIGARLDRLPLARFHYRIFGIISFSLLLTGFLSYSGNVV
                     LAKLVSNGWSNNFLNAAFTSALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAAT
                     GAAFVPDMYWLIFFRFLMGTGMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPM
                     LSAAIGVVVIAFFSWRIMFLLGGIGILLAWFLSGKYFIESPRWLAGKGRIAGAESQLR
                     EVEQQIEREKSIRLPPLTLNQSNSKVKVIKGTFWLLFKGEMLRRTLVAITVLIAMNIS
                     LYTITVWMPTIFVNSGIDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRLFGSALLI
                     IIAVLGYIYSIQTTEWAILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVN
                     AVGRIVAVFTPYGVAALLTHYGSITVFMVLGVMLVLCALVLSIFGIETRKVSLEEISE
                     VN"
     gene            complement(17716..18357)
                     /gene="pncA"
                     /locus_tag="LSX49_002212"
     CDS             complement(17716..18357)
                     /gene="pncA"
                     /locus_tag="LSX49_002212"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001587135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /protein_id="HBL7168614.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQE"
     gene            complement(18368..19384)
                     /gene="ansA"
                     /locus_tag="LSX49_002213"
     CDS             complement(18368..19384)
                     /gene="ansA"
                     /locus_tag="LSX49_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBL7168615.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLSKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQKLDTETIRKAMSQNLRGEL
                     TPDD"
     gene            complement(19516..20226)
                     /locus_tag="LSX49_002214"
     CDS             complement(19516..20226)
                     /locus_tag="LSX49_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310500.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HBL7168616.1"
                     /translation="MNKAPSLIAAIVLGLGISACGYFVGDGVKHLKTNNRYVNVRGLS
                     EKEVRADTAELTIAINFKGNIPGELFPKLEDAQKKIVAELNAQGINEKEITLGQWTSK
                     RTDSFYLKDDPTMPRYNADGSVTIKTHNVAAVEKVVAKLNELQVATEGAIAESKVAYR
                     FNGIGALRAEMIAAATKDARNAALQFATDSGSQVGSISDASQGVFQIFASGSDEDDPT
                     AINKTVRVVTTVTYALQD"
     gene            complement(20342..22198)
                     /gene="sppA"
                     /locus_tag="LSX49_002215"
     CDS             complement(20342..22198)
                     /gene="sppA"
                     /locus_tag="LSX49_002215"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707347.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBL7168617.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRQIPAQQVFPGAQGLLEGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKTLTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEVQQMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANVR"
     gene            22359..22910
                     /locus_tag="LSX49_002216"
     CDS             22359..22910
                     /locus_tag="LSX49_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HBL7168618.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDNKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            23027..24070
                     /gene="selD"
                     /locus_tag="LSX49_002217"
     CDS             23027..24070
                     /gene="selD"
                     /locus_tag="LSX49_002217"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBL7168619.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGVSFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKATAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            24075..26030
                     /gene="topB"
                     /locus_tag="LSX49_002218"
     CDS             24075..26030
                     /gene="topB"
                     /locus_tag="LSX49_002218"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL7168620.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETYKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTSVRQFRGIMAPGGGE
                     GKKKDSPRKRAPKKSPPSEEAGNGVII"
     gene            complement(26107..27450)
                     /gene="gdhA"
                     /locus_tag="LSX49_002219"
     CDS             complement(26107..27450)
                     /gene="gdhA"
                     /locus_tag="LSX49_002219"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBL7168621.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQVQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLSQGVI"
     gene            27686..27958
                     /locus_tag="LSX49_002220"
     CDS             27686..27958
                     /locus_tag="LSX49_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HBL7168622.1"
                     /translation="MSRALIAVVLAFPLITLANPHYHPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDQNYSEGAVIKAEGILLQCQRDDKTLSTNPLVWRRVKP"
     gene            complement(27924..28331)
                     /gene="nudG"
                     /locus_tag="LSX49_002221"
     CDS             complement(27924..28331)
                     /gene="nudG"
                     /locus_tag="LSX49_002221"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HBL7168623.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKIEPDES
                     QRQALVRELNEELGIEATVGDYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALRYPLAPADIPLLEAFMASRAARPAD"
     gene            28418..29038
                     /locus_tag="LSX49_002222"
     CDS             28418..29038
                     /locus_tag="LSX49_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBL7168624.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVAILLNRLLDGLDGALARRRGLTDAGGFLDISLDFLFYALVPFGFIL
                     AAPEQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGSET
                     ILLFVLSCLFPACFPWFAWVFGALCWMTTFTRVWSGYLTLKSLQRQ"
     gene            complement(29047..30354)
                     /gene="ynjE"
                     /locus_tag="LSX49_002223"
     CDS             complement(29047..30354)
                     /gene="ynjE"
                     /locus_tag="LSX49_002223"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YnjE"
                     /protein_id="HBL7168625.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLNEWIKQHNLKADAPVALY
                     GNDKDVDAVKTRLQKAGFTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKFYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPDQQVSFYCGTGWRAS
                     ETFMYARAMGWNNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(30421..31074)
                     /locus_tag="LSX49_002224"
     CDS             complement(30421..31074)
                     /locus_tag="LSX49_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL7168626.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAGQFSCTGELWLNEQRIDMLPTAQRQIGILFQDALLFDQFSVGQNLLLALP
                     ATLKGNARRNAVNDALERSGLDGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDNFRHWVFSEIRAMAIPVVQVTHDLQDVPPDSPVLDMAQWSENYNKLR"
     gene            complement(31074..32609)
                     /locus_tag="LSX49_002225"
     CDS             complement(31074..32609)
                     /locus_tag="LSX49_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7168627.1"
                     /translation="MATPLRYALIFLLWAMIAVIYAPLIPAALTLISPALSLTHWQAL
                     FADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVA
                     FATSALLLFADGGLLYDYFPYFTPPMDKLGIGLGLTLAVKESAFLLWILAAVLSEKRL
                     LQQLIVLDSLGYSRWQCLNWLLLPSVASALAMAMLAIVAWSLSVVDVAIILGPGNPPT
                     LAVISWQWLTQGDADQQTKGALASLLLMLLLAAYVLLGYLLWRGWRRTIPRVDGVRKP
                     ATPLLPSNTLASFLPLTGVLCVVLLAILADQSTINSQALINSLTMGLVAAFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLNLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPALIAFAVGFSVSIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVVKWVGYVRQ
                     GLR"
     gene            complement(32582..33748)
                     /locus_tag="LSX49_002226"
     CDS             complement(32582..33748)
                     /locus_tag="LSX49_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL7168628.1"
                     /translation="MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEVAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTEGAESPWGGAQLTFIARRD
                     VTLQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPTALKEAPDDA
                     TFARVTAPLWQYLDALHPYLWREGKDFPPSPARMDALLKANTLRLSLTFNPAHAQQKI
                     ASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFLLSPDAQLRKADPAV
                     WGDPSVLDPQKLPDGQRETLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH"
     gene            complement(33758..34306)
                     /locus_tag="LSX49_002227"
     CDS             complement(33758..34306)
                     /locus_tag="LSX49_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL7168629.1"
                     /translation="MGLPPLSKIPFILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSTDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRARLATHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPEKRS"
     gene            complement(34306..35013)
                     /locus_tag="LSX49_002228"
     CDS             complement(34306..35013)
                     /locus_tag="LSX49_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL7168630.1"
                     /translation="MMKMQSRKIWYYRITLIILLFAVLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGAFWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRNA"
     gene            complement(35027..35704)
                     /gene="ydjY"
                     /locus_tag="LSX49_002229"
     CDS             complement(35027..35704)
                     /gene="ydjY"
                     /locus_tag="LSX49_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416265.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdjY"
                     /protein_id="HBL7168631.1"
                     /translation="MLQHYSVSWKKGLAALCLLAVAGLSGCDQKENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMGYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKITE"
     gene            complement(35709..36419)
                     /locus_tag="LSX49_002230"
     CDS             complement(35709..36419)
                     /locus_tag="LSX49_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416264.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL7168632.1"
                     /translation="MNAERKFLFACLIFALVIYAIHAFGLFDLLTDLPHLQTLIRQSG
                     LFGYSLYILLFIIATLFLLPGSILVIAGGIVFGPLLGTLLSLIAATLASSCSFLLARW
                     LGRDLLLKYVGHSHTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLSHPKNEG"
     gene            complement(36586..37392)
                     /gene="xthA"
                     /locus_tag="LSX49_002231"
     CDS             complement(36586..37392)
                     /gene="xthA"
                     /locus_tag="LSX49_002231"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBL7168633.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPISVRRGFPGDDEEAQRRIIMAEIPSPLGN
                     ITVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRENPVLIMGDMNISPGDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMERLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
BASE COUNT         9381 a         9179 c         9709 g         9477 t
ORIGIN      
        1 tttagtcttt agctgttgca ttttgtttat gaaacagttc acggaacacc ggataaatat
       61 catcctggtc gcggatatgc tgcatcgcaa agttgtcgaa agtagattgc agatgctcat
      121 attctcgcca cagtgtctga tgcgcgcgac gtgtaatttc gatatagctg taataacgaa
      181 caacgggtaa tatttttttc gccagaattt catggcaaag cggagagtca tcggcccagt
      241 tatcgccgtc tgatgcttgg gctgcgtaaa tattccactg tgccgggtta taacgctctt
      301 tcactacctc atccatcagt tttagggcgc tggaaacaat ggtgccgcca gtttcctgcg
      361 agtagaaaaa ctcatgttca tcgacttctt tcgcctgggt atgatggcgg atgtatacga
      421 cttccacgtt cttatacgtt ctgctgagga acagatacag cagaatataa aaacgtttag
      481 ccatatcttt agtggactga tccattgaac cggaaacgtc catcaggcaa aacatcactg
      541 cctggctgga gggatcgggc cgtttttcgt agttcttgta acgtaaatcg aaggtgtcaa
      601 tgaaagggac gcgttcaatt ttggcacgta attctgcaat ttctttgcgc agacgttcct
      661 cttccagcag ttgcgcaggt tcactgttgc tgatgatggc caaattctct tccagcgcat
      721 gaagttcccg ccgcttgccc gccgtcatag ctgtgcgccg cgccagtgag ttctgcaatg
      781 aacgtacaac gctgatattg gccggaacgc cgttagcggt ataacccgcc cgatgcgttt
      841 tatattcggt cagctggcgt tgttggtttt gtttcagatt cggtaaggcc aaatcttcaa
      901 agagcagatc aagatactca tctttcgaaa tctgaaagac aaattcatcc tgaccttcac
      961 catcctggct ggcctggccc tgaccactgc cggaacctcc gccaccaccc tggggacgtt
     1021 caattcggtc gttctggacg aaatggtcat tgcccggatg cacacggtgg cgcaggcccc
     1081 cacgcccctg atgaaacatc ggttcgctaa tatcttccgt gggaatggat acggactcgc
     1141 cgctgtcgac gtcagtcacc gaacgcttat taatggcctc ggagatcgac tgtttaattt
     1201 gcgctttata acggcgtaag aaacgctggc gattcaccat gcttttattt ttgccgttca
     1261 gacgccggtc aataaaccag gtcatatgcc ccccgtacta catttgccaa cggtatgcta
     1321 cgcttgtgtt gccgcttctc tggcccacgg ttcgctgtcg ttgtaggccc ggtagcatgt
     1381 gtaccgggcc agggttgtta agacgattta cgtacgcgca aataccattc gcacagtaaa
     1441 cgcacctgtt tacgggtgta gcctttttcc atcatacggt cgacaaagtc gtcgtgtttc
     1501 ttctgctcgt cggttgacgt tttggcgtta aacgaaataa ccggcaacag ctcttcggta
     1561 ttggagaaca ttttcttctc gataaccgtg cgcagttttt catagctggt ccagttcgga
     1621 ttgcgtccgc tgttattcgc tctggctcgc agtacgaagt taacaatctc gttgcggaaa
     1681 tcttttggat tactgatccc cgccggtttc tcgattttct ccagctcggc gttaagagac
     1741 tcgcggtcaa acagctgccc ggtatccgga tcgcgatact cctgatcctg aatccagaaa
     1801 tccgcgtagg taacataacg gtcgaaaatg ttttgcccat attctgaata ggattcaagg
     1861 taggccgtct ggatctcttt gccgataaac tcggcatatt tcgggatcag ataacctttc
     1921 aggaactcca gatagcgttc agcctgctct tgcgggaact gctcgcgctc gatctgctgt
     1981 tccaggacgt agaacagatg gaccgggttt gccgccactt ctacatgatc gaagttgaac
     2041 acgcgggaga ggatcttaaa cgcaaaacgc gtcgacagac cgttcatccc ttcatcgaca
     2101 ccggcgtagt cacgatattc ctgatacgac ttggctttgg gatcagtgtc tttcagactt
     2161 tcaccatcat aaacgcgcat ctttgaataa atgctggagt tttctggctc tttcagacgc
     2221 gaaagaatag aaaaacgtga cagcgtttcc agcgtgccag gggcgcaggg ggcgtgagtc
     2281 aattcactgt gattaagcaa tttctcgtag attttgatct cttcggaaat gcgcaagcaa
     2341 tacggcacct tcacgatgta aacacggtcg aggaaggctt cgttgttttt gttattacgg
     2401 aaagtgaccc attcggattc gttcgagtgg gcgagaataa tcccgttgaa cggcagggcg
     2461 gagatacctt ccgtcccgtt gtagttacct tcctgggtgg cggttaacaa gggatgcagc
     2521 acttttatcg gtgctttaaa catctcgaca aattccatga tcccctgatt ggcgcggcac
     2581 agcgcaccgg aatagccgta ggcgtccggg tcattctgcg cgtagtgttc gagtttacga
     2641 atatcgactt tccctaccag ggcggagatg tcctggttgt tctcatctcc gggttccgtt
     2701 ttggcgatgg caatttgttg cagaattgac ggccagacct tcactacccg gaacttagtg
     2761 atatcgccac caaattcatg caggcgcttt gccgcccacg gcgacatgat ggtgccgaga
     2821 taacggcgag gaatgccgta ctctttttcc agaatctgcg catcttcctg cggattgaaa
     2881 agacagaacg gatgatcgtt gaccgggcta cgctcaccgt tggcgctcaa tacataaatc
     2941 ggtacgagct gcattaatga tttcagtcgc tcagcaagtg atgatttacc cccacccaca
     3001 ggccccagca gatacagaat ttgtttcttc tcttccagcc cctgagccgc gtgtttcaga
     3061 taagaaacaa tctgttcaat cgcgtcttcc atgccgtaaa actcttcaaa cgccggataa
     3121 cgtgcaatga cccggttaga aaagagtcga gaaagtctgg gttcctgggc tgtatcgacc
     3181 atgacaggct caccaatagc catcaatagc cgctcagccg cgttggcata agcactgcga
     3241 tcttgccgac aagtggtaag aaactcctgc agtgtgaact cttcgtcctt ggcagcttca
     3301 tatcgctggc gatagtgatc gaatatattc atggtatgcc gtcctttcgt tttttagcac
     3361 aggttaagag ccgttcatat gaatagtaga ggctcccgga agaggtaaac tgaacgacgt
     3421 ctcttgctaa aacacagcaa ctctcatgcc attttattga cgatgagaac aacgtgcccg
     3481 gtgatacacc ttcaaaatta agcgtagatg gcaaatggaa aacttgcctg cacggctttc
     3541 ttaatttcaa tggcatatca acaactcatc cataaatttt gcataattaa tgtaaataat
     3601 agggtcgccg gtaacgctaa attcatttgg ctgtaagcgt ggtgtcatct gcgtcaggaa
     3661 aattaaacag ttactataaa aaatgaaaac gtaaaaaggt tgggtttcga tgtattgacg
     3721 ggtaaacttt gtcgcccgct aaacatttgt ttaaggaatg attaattgtg accaaactca
     3781 aacttctggc acttggagtg cttatcgcaa cgtctgcagg cgtagcgcac gctgaaggta
     3841 aattttccct gggcgcaggc gtaggtgtcg ttgaacaccc atataaagat tacgataccg
     3901 atgtttaccc agtaccggta atcaactatg aaggcgataa cttctggttc cgtggcttag
     3961 gtggtggtta ctacctgtgg aatgacgcga cggacaaact ttcaattacc gcttactggt
     4021 cgccgcttta cttcaaagct aaagacagtg gcgatcacca aatgcgtcac ctcgatgacc
     4081 gtaagagcac catgatggct ggtctgtctt atgctcactt tacccagtac ggttacctgc
     4141 gtaccaccct ggctggcgat accctggata acagcaacgg catcgtctgg gatatggcct
     4201 ggttgtatcg ttacaccaac ggtggcctga ccgtgactcc gggtattggt gtgcagtgga
     4261 acagcgaaaa ccagaacgaa tactattatg gcgtatcgcg caaagagtcc gctcgcagcg
     4321 gtctgcgtgg ctataacccg aacgacagct ggagccctta cctggagctg agcgccagct
     4381 acaacttcct cggcgactgg agtgtttacg gtaccgcgcg ctacacccgt ctgtctgatg
     4441 aagttactga cagcccaatg gtggataaat cctggactgg cctgatttct accgggatca
     4501 cctacaaatt ctgataatgc atctttccag ggcattttgt gcataaaaac agggcgtaat
     4561 gccctgtttt gcattacggt ggtgcaatac ctgggaggaa acaatgcaac aaaaaatgat
     4621 tcaatttagt ggcgatgtct cactgccagc catagggcag ggaacatggt atatgggcga
     4681 agatgccagt cagcgtaaaa cagaagttgc tgcactacgc gcgggcattg aactcggttt
     4741 aaccctcatt gataccgccg aaatgtatgc cgatggcggt gccgaaaaag tggttgggga
     4801 agcattaatc ggtctgcgtg agaacgtctt tctcgtctct aaagtctatc cgtggaatgc
     4861 tggcgggcaa aaagcgataa atgcatgcga agccagttta cgccgtctca atactgatta
     4921 tctcgatctc tacttattac actggtctgg cagtttcgct ctcgaagaga ctgtcgcagc
     4981 gatggaaaaa ttgatcgccc agggaaaaat ccgccgctgg ggcgtttcta accttgatta
     5041 tgccgatatg caggaactct ggcagctgcc ggggggaaat cagtgtgcca ctaatcaggt
     5101 gctttaccat ctcggttcac gagggattga gtacgatcta cttccctggt gccagaaaca
     5161 gcagatgccg gtgatggctt acagtccatt agcccaggcc gggcggttgc gcaatggact
     5221 gttaaaaaat gcggtagtca acgaaattgc acatgctcac aatatcagtg cggcacaagt
     5281 attgttggcg tgggtaatca gccatcaggg tgtgatggcg attccaaaag cggcaactgt
     5341 cgcacatgtc caacaaaatg cggctgtgct tgaggttgaa ctttcgtcag cggaattagt
     5401 tatgctggat aaagcgtatc cggcaccaaa aggaaaaact gcgctggata tggtgtgatg
     5461 ttgattcgtg ccggatgcat cgcacccggc acacaatatt aacgcaaatt aacgtttagc
     5521 aacgcgaatg gattgcgcca gatgtgcagg tttctctttg gtgacttttt gcgtttctga
     5581 agcgtaagcc gtttctacac aaacaaaggt cttgtagcca tcatccggca tatcgcccat
     5641 gctaactgaa agcgccggtc ctgggttcca gcctacaacg ttcagatgat gctggtggcc
     5701 tacggcgata atacgattca gcgcttcgtc attaattacg ctgcaatctt gcggattcag
     5761 atacacgcga tcggtacggt cagggaaggt ctgaataccg tcggtcagta catcttcttt
     5821 cgcgtcattt actttatcaa tgaagcgatc gcctagtcca ctgacgctta ccttagcgat
     5881 atcacccacg ttaaagtagg tatgcagagc agaggtagtt tcaaattcgc cgtgtgcttc
     5941 aagatcgatt tcacaggttt tacccacgtg gaaatgcgct aacagcgtaa agtcgtgcgg
     6001 ccagaatttt ttcgtctctt cgctttgtgt caattcaaaa gtcagcgcta caccatcagc
     6061 atcttcacga tgtgatttca gcgtccacgg caggttgcgg gcaaaaccgt gcgcaggcag
     6121 accttgttgt gcagccggac caaaccacgg ccagcaaacc ggtatgccac cgcgaatggc
     6181 gacgccattt ttgaacggtg tgttgttact caaccacaga acttcttctt cacccgcagg
     6241 tttccacgag agaaggtgtg cgccctgtaa tgcaaaagag gcttttacct ggggatgatc
     6301 gaccacaatg aggtccagtt catccagttt acgacgggag aggacagggg agatttgttc
     6361 gatgaccgga agggcaaaaa ttttcttaat catgacgcag tcctttaact tcattttatc
     6421 aggtaaaaaa aagagcgacc gaagtcgctc tttttagatc acagtgtcat ctcaacttat
     6481 ttggagatgt gagcgatcag gtccagaact ttgttggagt aaccggtttc gttgtcgtac
     6541 caggatacca gtttcacgaa gttgtcgttc agagcgatac ccgctttagc atcgaacacg
     6601 gaagtgcaaa cttcgccgtt gaaatcggta gatactacgt catcttcggt gtagcccaga
     6661 acgcctttca tttcgccttc agcagcagct ttaacggcag ctttgatctg ctcgtaagtt
     6721 gcagcttttt ccagacgaac ggtcaggtca actacggata cgttcggggt cggaacgcgg
     6781 aacgccatac cagtcagttt gccattcagt tctggcagta ctttacctac agctttagca
     6841 gcaccggtag aagacgggat gatgttctgg gaagcgccgc ggccgccgcg ccagtctttg
     6901 tgagacgggc catcaacggt tttctgagta gcggtagtag cgtgaacggt ggtcatcaga
     6961 ccttcgatga tgccgaagtt atcgttgata actttagcca gcggagccag gcagttggtg
     7021 gtgcaggatg cgttggaaac gatgtcctgg ccagcatatt tgtcgaagtt agcgccttta
     7081 acgaacatcg gagtgttgtc tttagacgga ccagtcataa ccactttctt cgcaccagcg
     7141 gtgatgtgtt tacgagcagt ttcgtcagtc aggaacagac cagttgcttc agcgacaacg
     7201 tcaacaccaa cttcgtccca tttcaggtta gccggatcac gttcagcggt aacacggatt
     7261 tttttaccgt taacgatcag atgaccgtct ttcacttcaa cggtaccgtc gaaacggccg
     7321 tgagtggagt catatttcag catgtatgcc atgtaatcag cgtctaacag gtcgttgatt
     7381 gcaacgatct cgatgtcaga acgtttctga gcagcacgga aaacaatgcg accgatacgg
     7441 ccaaaaccgt tgatacctac tttgatagtc atatattcca ccagctattt gttagtgaat
     7501 aaaaggttgc ctgtaaaatt acaaaaacct tacgcagcgt caagcggaat cgtgtcaatc
     7561 attgcgacaa atcaatcctg tgcctaagca ttacgcgact gactcgcctc actcttcctt
     7621 tgggcttgag accacatggg gtcggcgccc cgaattttaa agggcaatta cgataaaaat
     7681 gtgattttca tcacgattta ggtgcagcca tttcgtcgag atcaagttta ggacaaaatt
     7741 ttgccagttg gtgttaatgt tttgttagaa tcagtcacgt aatgtgagca cgattaaagt
     7801 gagatgtgag caaatggcta ataaaccttc ggcagaagaa ctgaaaaaaa atttgtccga
     7861 gatgcagttc tacgtgacgc agaatcatgg gacagaaccg ccatttacgg gtcgtttact
     7921 gcataacaag cgtgacggcg tatatcactg tttgatctgc gatgccccgc tgtttcattc
     7981 ccaaaccaag tatgattccg gctgtggctg gcccagtttc tacgaaccgg tgagtgaaga
     8041 atctattcgt tatatcaaag acttgtcaca tggaatgcag cgcatagaaa ttcgttgcgg
     8101 taactgcgat gcccatctgg gccatgtctt tcctgacggg ccgcagccaa cgggcgaacg
     8161 ttattgtgtt aactctgctt ctttacgctt cactgatggc gaaaacggcg aagaaatcaa
     8221 cggttgaaaa aacgattcag caacttattc cacaggagcg gaaaaattat gaatcttgat
     8281 gacattatca acagcatgac gcctgaggta taccagcgtt tgtcgaccgc cgttgaactg
     8341 gggaaatggc ctgatggcgt tacgttgacc gaggaacaaa aagagaactg cctgcaactg
     8401 gtgatgctgt ggcaagcccg ccataatacc gaagcacagc atatgacaat tgacacaaat
     8461 ggtcagatgg tcatgaagag caaacagcag ttaaaagaag attttggtat ctcagcaaag
     8521 cctattgcca tgtttaagta agtggtttat cccctttttg ccgcggttat aaaggggata
     8581 gccaacaatg accccacgac tcatctcaat tatctcgccc cgacctggct aagtcccagt
     8641 ccgatctctt gcagtcgcgt tcacacctga atgacttctc ctgaacttaa gtctcaggcc
     8701 tatttggccg ggaatccctc tcgaatttgc tctttttgcg tcccgccttc catcaacctg
     8761 taacaacccc agccattttc tgcgtaattg tgatctaagt tgtaaaacgc agatcattat
     8821 ctgtgtttta cagatttaat gttgacctca aaaatcatgt gggtaagtat gatgaccatc
     8881 taagcaaaac aaaacacaga ggatgacgca atgaaagcac tggctcggtt tggcaaggct
     8941 tttggtggct acaagatgat tgatgtccca caacccattt gtggcccgga agatgtcgtg
     9001 attgaaatta aagccgcggc aatctgcggc gcagacatga agcactacaa tgtcgatagc
     9061 ggttcggatg agtttaactc tatccgcggc catgagttcg caggttgtat tgcgcaggtt
     9121 ggtgaaaaag tcaaagactg gaaagtgggg caacgcgtcg tgtcggataa cagcggtcac
     9181 gtttgcggcg tttgcccggc ctgtgaacaa ggtgattttc tgtgttgtac agaaaaagta
     9241 aaccttggtc tggataacaa tacctggggc ggtggttttt ccaaatattg tcttgttcct
     9301 ggtgaaattc tcaaaattca tcgtcatgcg ttgtgggaaa tccctgatgg tgttgattat
     9361 gaggacgcag ccgtacttga ccctatctgt aatgcctata aatccatcgc gcagcaatcg
     9421 aaattccttc caggtcagga tgtggtcgtc atcggcactg gcccactcgg gctgttctcc
     9481 gtacaaatgg cgcggattat gggggcggta aatatcgtcg tcgttggtct gcaagaagat
     9541 gtaacggtcc gcttcccggt tgcaaaagaa ctgggtgcga cggcagtagt aaatggttct
     9601 accgaagatg tggtggcacg ctgccagcaa atttgtggca aagacaatct ggggctggtg
     9661 attgaatgct ccggtgccaa tatcgcattg aaacaagcca tcgaaatgct ccgcccgaat
     9721 ggggaagtag tacgcgttgg aatgggcttc aaacctcttg atttctcgat taatgacatt
     9781 accgcctgga acaaaagcat cattgggcat atggcctatg actccacttc atggcgtaac
     9841 gctatcaggc tattagccag cggcgctatc aaagtcaaac cgatgatcac gcatcgtatc
     9901 ggcctgtcgc aatggcgcga agggtttgat gcgatggtcg ataaaactgc aatcaaagtg
     9961 atcatgactt acgactttga tgaataacta ctctcctgaa ggaacgttat cgcatggaac
    10021 agataacaaa accgcattgt ggtgcacggc tggatcgctt accggattgc cgctggcatt
    10081 cgtcgatgtt tgccatcgtc gcgtttggcc tgcttgtctg ctggagtaat gccgttggtg
    10141 gcttgatcct cgcgcagctg aaagcgttgg gctggacaga taattccacc actgccacat
    10201 tctcagcaat cacgaccgcc ggaatgtttc tcggtgcgct ggtgggcggc atcatcggtg
    10261 acaaaaccgg tcgcagaaat gcgtttatcc tctatgaggc cattcatatt gcctcgatgg
    10321 ttgtcggtgc tttctcaccg aatatggatt tccttattgc ctgccgtttt gtgatgggcg
    10381 ttgggctggg agctttactg gttacactgt ttgctggttt caccgaatat atgcccggaa
    10441 gaaatcgcgg aacgtggtcc agtcgggttt cctttattgg taactggtca tatccgctct
    10501 gttcattgat tgcgatggga ctcacgccgc tgattagtgc agagtggaac tggcgggtac
    10561 aactgcttat ccctgcaata ttgtcactta tcgctacggc gctggcctgg cgctactttc
    10621 ctgaatcccc gcgctggctg gaatcgcgcg gacgttatca ggaagccgag aaagtcatgc
    10681 ggagtataga agaaggcgtc atacgccaga cgggtaaacc tttgccgcct gtggttattg
    10741 ctgatgacgg taaagcacca caagcggtgc cgtattcagc cttactgaca ggagtattac
    10801 tgaaacgcgt gatattaggc tcttgtgtgc tgattgccat gaacgttgtg cagtacacac
    10861 taattaactg gttgccaacg atattcatga cccagggaat taatttaaaa gactcgattg
    10921 ttttaaatac catgagtatg tttggcgcgc catttggtat ttttattgcc atgctggtga
    10981 tggataaaat tccgcgtaaa acaatgggtg tggggctatt aatcctgatt gcggtgctcg
    11041 gatatatcta ttcactgcaa accagtatgt tgctcataac gctgattggt ttcttcctga
    11101 ttactttcgt ctatatgtac gtttgctatg cctcggcagt gtatgtccct gagatctggc
    11161 cgacagaggc caaactccgt ggctccggtc tggcgaatgc ggtagggcga atcagtggta
    11221 ttgccgcacc ttatgccgtt gcagtgctgc tcagtagtta tggcgtaacg ggagtcttta
    11281 ttcttctggg ggctgtttca attattgtcg caattgctat cgccaccatt ggaattgaaa
    11341 ccaaaggtgt ctccgttgaa agtttaagta ttgatgcagt agccaataaa taatactggt
    11401 ggattcaaaa tgaaaaattc aaaagcaatg ttgcaggtgc cgggcacaat gaaaattatt
    11461 tcagcagaaa tacctgtacc taaagaagat gaagttttga ttaaagtgga atatgtcggt
    11521 atttgtggtt cagatgtaca tggttttgaa tcaggcccgt ttattcctcc taaagaccca
    11581 aatcaagaaa ttggcctggg tcatgaatgc gccgggacgg ttgtggctgt gggaagccgc
    11641 gtgcgcaaat ttaaaccggg ggatcgggta aatatcgaac ctggcgttcc ttgcggtcac
    11701 tgtcgttact gtctggaagg caaatataac atctgcccgg acgttgattt tatggcgaca
    11761 caacccaact accgcggcgc attaacgcac tatctgtgtc atccggagag ctttacttac
    11821 aaactgccag acaatatgga cacgatggaa ggggcgctgg tggagcctgc cgcagtcggg
    11881 atgcatgccg cgatgctggc agatgttaaa ccgggtaaga agataattat tctgggagcg
    11941 ggttgtattg gtttgatgac gttgcaagcg tgcaaatgcc tgggagcaac ggaaattgcc
    12001 gtcgttgatg tgctggaaaa acgtctgaca atggcggaac agctcggcgc gacagtggtt
    12061 attaacggcg caaaagaaga cactattgca cgctgtcagc aatttaccga agacatgggc
    12121 gcagatattg tttttgaaac agcgggttct gcggtcaccg ttaaacaggc accttatctg
    12181 gtcatgcgcg gcggtaaaat tatgattgtt ggtactgtac ccggcgattc ggcaatcaat
    12241 ttcctcaaaa tcaatcgcga agtcactatc cagacggtat tccgctatgc caatcgttat
    12301 ccggtcacga ttgaagctat ttcttcaggg cgattcgatg tgaaatcgat ggtgacgcat
    12361 atttacgatt atcgggatgt acaacaggca tttgaagagt cagttaacaa caaacgcgac
    12421 attattaaag gcgttattaa aattagcgat taattaatac gggagaacag aacatgctcg
    12481 cagatatcag atattgggaa aacgatgcca caaataaaca ttatgcaatt gcccatttta
    12541 acgtatggaa tgcagaaatg ttgatgggcg ttatcgacgc agccgaagaa gcgaaatcac
    12601 cggttattat ttcttttggc acaggttttg tcggcaacac ctcatttgaa gatttctctc
    12661 acatgatggt atcaatggca caaaaagcaa cggtgccggt aataactcat tgggatcatg
    12721 gtcggagtat ggagattatt cataacgcct ggactcatgg tatgaattca ttaatgcgtg
    12781 atgcttctgc atttgatttc gaagaaaata ttcgtttaac caaagaggct gttgatttct
    12841 tccatccgct gggtattccg gtagaggcgg aattagggca tgtcggtaat gaaaccgttt
    12901 atgaggaagc gctggcaggc tatcactata ccgatcctga ccaggcggct gaatttgttg
    12961 aacgtacggg ctgtgactca ttggctgtcg ccatcggcaa ccagcatggg gtttatacgt
    13021 cagagccaca attgaacttt gaggtcgtca aacgcgtacg cgatgctgtt tctgttccgc
    13081 tggttttgca tggcgcatca gggatcagtg atgccgacat taaaactgca atttcgttgg
    13141 gtattgcgaa aatcaacatt catacggagc tctgtcaggc cgcaatggta gcagtgaaag
    13201 aaaaccagga tcagcctttc ctgcatttag aacgtgaagt gcgtaaagct ataaaagaac
    13261 gggcattgga taaaattaaa ctgttcggtt ctgatggcaa agcggaataa taatatggat
    13321 aatctcgacg ttatttgtat aggtgccgct attgttgata ttccattgca accggtcagt
    13381 aaaaatatct ttgatgtgga ttcttatcct cttgaaagaa tcgcaatgac caccgggggt
    13441 gatgcaataa atgaagcaac aattatttct cgtctgggcc atcgcacagc attaatgagt
    13501 cgtattggta aagatgccgc agggcaattt attctcgacc attgccgcaa agagaatatt
    13561 gatattcaaa gcctgaagca ggacgtcagc atagatacct ctattaacgt tggactggtg
    13621 acggaggatg gcgagcggac ctttgtcaca aaccgtaacg gcagtctgtg gaaattgaat
    13681 attgacgatg ttgattttgc gcggttttct caggcgaaat tattatcact ggccagtatt
    13741 ttcaacagtc ctctattgga tggtcgagcg ctaacagaaa tttttacgca agctaaaacc
    13801 cggcagatga ttatctgtgc cgatatgatc aaaccgcggt tgaatgaaac gctgaatgat
    13861 atttgcgaag cattgagtta tgtcgattat ctgtttccta attttgccga ggcaaaatta
    13921 ctcaccggga aagagacact ggatgaaatt gctgactgct ttcttgcgtg cggcgtaaaa
    13981 acggtggtga ttaaaacggg taaagacggc tgctttatca agcgtggtga catgacgatg
    14041 aaggtgccgg cggtcgcagg aataaccgct atcgacacca ttggtgcggg cgataacttt
    14101 gcttcaggtt ttattgcagc actgttagaa ggcaaaaatc tgcgagaatg cgcacgcttt
    14161 gccaatgcaa cggcggctat ctcggttcta agcatcggcg ccaccaccgg tgtaaaaaac
    14221 agaaagctgg tcgaacaatt gctggaagaa tacgaaggat aatgaaggca aatgaaaaag
    14281 atacctttag gcacagcgga tataacgctt tcgcgaatgg ggttgggtac atgggctatt
    14341 ggcggcggtc ctgcatggaa tggcgatctc gatcgacaaa tatgcattga tacgattctt
    14401 gaagcccatc gttgcggcat taacctgatt gatactgcgc caggatataa ctttggcaat
    14461 agtgaagtta tcgttggtca ggcgttaaaa aaactgcccc gtgaacaggt tgtagtagaa
    14521 accaaatgcg gcattgtctg ggaacgaaaa ggaagtttat tcaacaaagt tggcgatcgg
    14581 cagttgtata aaaacctttc tccggaatct atccgcgaag aggtagaagc cagcttgcaa
    14641 cgtctgggta ttgattacat cgatatctac atgacgcact ggcagtcggt gccgccattt
    14701 tttacgccga tagctgaaac tgttgcagtg cttaatgcgt taaaggccga agggaaaatt
    14761 cgcgctatag gcgctgctaa cgtcgatgct gaccatatcc gcgagtatct gcaacatggt
    14821 gaactggata ttattcaggc gaaatacagt attctcgacc gggcgatgga aaacgaactg
    14881 ctgccgctat gtcgtgataa tggcattgtg gttcaggttt attccccgct agagcaggga
    14941 ttgttgaccg gcaccatcac gcgtgattac gttccgggcg gcgctcgggc aaataaagtc
    15001 tggttccagc gtgaaaacat gctgaaagtg attgatatgc ttgaacagtg gcagccactc
    15061 tgtgctcgtt atcagtgcac aattcccact ctggcactgg cgtggatatt aaaacagagt
    15121 gatttaatct ccattcttag tggggctact gcgccggaac aggtacgtga aaatgtcgcg
    15181 gcactgaata tcaacttatc ggatgcagac gcaacattga tgagggaaat ggcagaggcc
    15241 ctggagcgtt aaatactcaa cacgattcac ctctgtttct gtgaaaactg tgatgaaaat
    15301 ctgtgattca aacaggttat tttgaaagta aacatcggtt atgcgataat tgcgctaatg
    15361 tgatgtaaaa agatacaggg gtgtaatcgt ggcggcaaaa gacaggattc aggcaattaa
    15421 gcaaatggtt gccaacgata aaaaggtgac agtctcaaat ttgagtggga tttttcaggt
    15481 aaccgaagaa accattcgcc gcgatcttga gaagttggaa gatgaaggct ttttgaccag
    15541 aacctatggt ggtgctgttt taaatacagc gatgttgacg gagaatatcc atttttataa
    15601 gcgcgcttca tcgttttatg aagagaagca gcttattgca cgcaaggcac taccctttgt
    15661 cgacaataaa accaccatgg cagccgattc cagtagtacc gtaatggaat tgctcaaatt
    15721 gttacaggac cgtagtgacc tgacgttgct aaccaactcg gcggaagcga ttcatgttct
    15781 ggctcagtca gaaattaaag tcgtttcaac gggtggggaa ctaaacaaaa atacactttc
    15841 actgcaagga agaattacta aagagatcat cagccgctac catgtcgata tcatggtaat
    15901 gagttgtaaa ggtcttgata ttaacagcgg cgcgctggac tctaatgaag cggaagctga
    15961 aatcaaaaag acaatgatcc gtcaggcgac agaagttgcg ttattggttg atcactctaa
    16021 gtttgatcgc aaagcttttg tccagttagc tgactttagt catattaatt acataataac
    16081 tgataaatca ccgggtgcag agtggatagc attttgcaaa gacaataata tccagctggt
    16141 gtggtaattt aagcacacat tgtcaatatt atttgttcct gcgcctggaa ataaaatgat
    16201 gataaagatg cggcaagtga atttgccgca attgctacct tttttagcaa atccgaggca
    16261 cccaatggaa caatatgatc aaattggcgc aagactggac cgcttgcctt tggcccggtt
    16321 tcattatcgt atatttggta taataagctt tagtctgtta ttaacggggt ttttgagtta
    16381 ctccggtaat gtcgtcttag caaagctggt aagcaatgga tggtcaaata atttcctcaa
    16441 tgccgccttt acctcggcat taatgtttgg ttatttcatc ggctctctta ccggtgggtt
    16501 tattggtgac tactttgggc ggcgcagggc gtttcgcata aatcttctca tcgtcggtat
    16561 tgcggcaaca ggggccgctt ttgtccctga tatgtactgg ctcatcttct ttcgcttcct
    16621 gatgggaaca ggaatggggg cgctgattat ggttggctat gcctcattta cggagtttat
    16681 ccccgcgacg gtgcgtggaa aatggtccgc gcggctctca tttgttggaa actggtcgcc
    16741 catgctgtct gcggcgatag gcgtggtggt tatcgctttt tttagttggc ggataatgtt
    16801 tctgctgggc ggtattggca tactgttagc ctggtttctc tcaggtaaat actttattga
    16861 gtcgccacga tggttggcag ggaaagggcg aatcgcaggt gcagaaagcc aacttcgtga
    16921 agtagagcag caaattgaaa gagagaagag tattcgttta cccccgctta ctttgaacca
    16981 gagcaacagc aaggttaagg taatcaaggg taccttctgg ctcctgttta aaggggaaat
    17041 gttacgacgt acattagtcg cgattactgt tttaattgca atgaacattt cgctttatac
    17101 catcaccgta tggatgccga ccatatttgt taactccggc attgatgtcg ataaatcaat
    17161 attaatgacc gctgttatta tgattggcgc tccggtaggg atatttattg cggcattaat
    17221 tattgatcat ttccctcgtc gattatttgg ttccgcctta cttattatta ttgccgtgtt
    17281 aggctatatc tattcaattc agacaacaga gtgggcgatt ttaatctatg gcctggtgat
    17341 gatcttcttt ttatacatgt atgtttgctt cgcgtcggcg gtttatatcc cggaactttg
    17401 gccaacgcat ttacgcctgc gtggttcggg tttcgttaat gccgtaggac ggatcgtcgc
    17461 agtcttcacg ccctatggcg ttgcggcatt attaacacat tatgggtcga tcacggtgtt
    17521 tatggtgctt ggtgtcatgt tagtgctctg tgcgctggtt ctctccattt ttggcatcga
    17581 aacgcggaag gtgtcgctgg aagagatttc tgaggtgaat taaatctttc gttgatggcg
    17641 tcaattacca gatgtatcac tgatgtgttt tatctggcct acaatgccag tacagaattg
    17701 taggccagcg taaaattact cctgcgtttc ttcccagtct gccagcgtat atagcgttgc
    17761 cccagctgct gacatttcca taaacgcgtg cgcactgtcc tgtggctgga tatttacgcc
    17821 acgacaacca tcggtaatca cgttcacctt atagcctaac tgtaaagcgt ccagcacggt
    17881 aaacttaacg caatagtcag tagccagacc cataacgatc aattcattga ttacatgagc
    17941 gcgcaaccag tcatcgagcg cagttttctg ccgacgaccg ttatcaaaaa aggcactgta
    18001 actgtcaact aaaggatttt cgcctttatg gaacaccgct gcgatcgctt tttgcttcag
    18061 taacggatgt aattgtgcgc cttcactgtt ctgcacacag tgatcgggcc agaaggtttg
    18121 tggcaaaccg tcgagttggc ctggcgtata aggctctaca ccgtgctgac tggcaaaact
    18181 gccgtgattc gccggatgcc agtcctgact ggcgataact gcttcaccgc gcgactggca
    18241 ccagtcaatc aggcggttag cgacatccac cgtactgtca ccttccggca cggcgagcgc
    18301 gccaccagca cagaaatcat tttgtaaatc gaccagtaac agggcgcgag ggggcattgc
    18361 agtctcctta atcatccggc gtcagttcgc cacgcaggtt ttggctcatg gccttgcgaa
    18421 tggtttcagt atcaagtttc tggctaagca ggtaatgcag tttggttagc gtggcttcta
    18481 cagtcatatc tgcaccgcca ataacgccgg catgggcgag ggcgttaccg gtggcataac
    18541 cacccatgtt cactttaccg gacatacatt gtgtcaggtt gaccaccaca ataccgcgat
    18601 cgctggcttc ttgtaattcc tgcaggaagg ctttgttttg tggcgcatta cccacgccat
    18661 atgagcgcag aatcaatgct ttcacaggtt ggcgcagaaa attgcgcacg acgtcagcag
    18721 aaatccccgg ataaatcgtc actacgccaa ttggttgcgg cgtgattgga tgaacgatca
    18781 attccccttc gccgtgcggg gcgggtggcg tattcaaacg acgaatatgg atacctgctt
    18841 ccagtaacgg aggaaggttt ggagaggcaa acgcatcaaa accatcggca tgggctttgg
    18901 tggttcggtt gccacgatac agtcgattat taaaaaagag agttacttcg ttgataggat
    18961 aattcgccgc aacgtacaac gcattcagca gattaatttg tccgtcagag cgtaactcag
    19021 ccagcgggat ttgtgaccct gtcacaatga ccggtttact gagattctcg agcatgaacg
    19081 acagtgcaga ggcggtatac gccatcgtgt ctgtgccgtg cagaatgaca aaaccatcat
    19141 agtcgtcata gtgcgcttta atatcttcag caatatgctg ccagtcttct ggcgtcatat
    19201 cagaagaatc catcaatggc gtatattcat gaatggtgaa atctggcatc tccgggcgat
    19261 ggaattccgg catcagcgcc agttggcgct gtagatgacc tgacaccgga atataaccct
    19321 gctcggaacg ctgcatcccg atggtcccgc ccgtgtaggc gacgtaaatt gatttctttt
    19381 gcatgatatt gatatgaatg atatcgaaag agcaaaagta tatacgtgag gggcagcgag
    19441 cgcacctgga tactctgtgg atatgagaaa agtccggcag aacggaggga ttagtgtccc
    19501 gccggagaaa agtggttaat cctgcaacgc ataggttacg gtggtgacta cgcgtaccgt
    19561 tttattaatc gccgtaggat catcttcatc actgccactg gcgaagatct ggaacacgcc
    19621 ttgtgaggca tcgctaattg accccacctg gctacctgag tccgttgcaa attgtaatgc
    19681 tgcgttgcgt gcatctttgg tggcggcggc aatcatctca gcgcgcagtg cgccaatacc
    19741 attaaagcga taggcgactt tgctctcagc gatagcgccc tccgtagcga cttgcagttc
    19801 gtttaatttc gcgacgactt tttcgacagc agcaacatta tgggttttta tcgtcactga
    19861 cccgtctgcg ttatagcgtg gcattgtggg atcatctttc agataaaagg aatctgttcg
    19921 cttgcttgtc cattggccca gggttatctc tttctcgtta atcccctgag cattgagttc
    19981 ggcaacaatt tttttctgcg cgtcttccag tttcgggaac agttcgccgg gaatattacc
    20041 cttaaagtta atcgcaattg ttaattctgc cgtatctgcg cgaacttctt tttcagaaag
    20101 cccacgcaca tttacataac ggttattggt ttttaaatgt ttaacaccat cgccaacaaa
    20161 ataaccacag gcgctaatcc ccagtccgag gacgatagcg gcaattaaag agggggcctt
    20221 attcactgat gactccatat cagatgctaa atgagcaagg gaatgtagtg gagagaggga
    20281 gtgaaagaca gtccgattca ggagtgtggc cgacagcata tcggccacat ttttgcagga
    20341 cttaacgcac gttggcgcag gtcaggcaaa acgcataacg gttttgtggg tcgttaaacg
    20401 cggccagctt gtcgctttca cttttaacgg tagaggctac cgaggccagc ggtgcaggta
    20461 acatggcctg gaacgcatct ggcaacattg cccggacaga accagacatg ttgtccatca
    20521 ctttgtcgaa gaaggtcggt tcatcaacgt agtattccag atgccactgt ttcacttttg
    20581 ccagctctgc tgctttggcg accgcatcat cgaaatcccc gagactatcg accagcccgt
    20641 tagcttttgc atcctgaccg gtccagacgt ggccctgggc gattttatca atctgctccg
    20701 gcgttgaatg acgcgcatca gcaaccagcg tgataaagcg tttatagcca ttctcaatgc
    20761 ttaactgcat catctgctgc acttccggcg gcagtgccct ggtgatagaa acatccgcca
    20821 gcggtgaagt tgagacacca tcagtatgaa caccaatcga atccagacta ttttctacgg
    20881 tggtgatcac gccgaagata ccgatagaac cggtcagggt gctggggtta gccacaatgt
    20941 aattagctgg tgtggaaatc cagtaaccac cagatgccgc catgccaccc atcgatacaa
    21001 ccacaggctt acccgctgcc cgggctgctg ccagttcagc gcgaatcact tcagacgcgg
    21061 taacgctgcc gccgggacta ttaacacgca gaacaatcgc tttcactttc gggtcaaggc
    21121 gagcgtcgcg gatttgtgcc gcagtggtat caccgccaac attcccctga gtttcctcgc
    21181 catccataat tgcgccatta gcgaagacga caccgatact gtcaccggta tctgccggcg
    21241 ttttcaatgc gtaatcgtaa taactgatgg cgcgataatt tttatcagtt ttactccagc
    21301 cgaactcttt ggtcagagtt ttttcgattt cggcactcga tgccagtgca tcgaccagct
    21361 tgttttccag cgcatatttc gcggtatcgc caccggtttt ggttaaaccc tcaagcaacc
    21421 cttgcgcgcc agggaatacc tgctgagcag ggatctggcg gttagcggca acagtattca
    21481 gatagttttg ccacagctca ccaatccagc ggctgtcagc ttcgcgggct gccggcgaca
    21541 tatcatcacg aataaacggt tcaacggcag atttatacgt acccacgcgg aacacatggg
    21601 tggaaacttt cagcttatcc agtaacgatt tgtagtacag accgttggtg gcaaagccgt
    21661 gcagatcaac cacgccttgc ggagacagcc aaattttatt ggcgaaactg gcgagataat
    21721 attgcccctg gctgtagttc tcgccaacgg cataaaccgg tttcccgctg tcacgaaact
    21781 ctttcagagc tttgccgatg tactgcatag acggctggtc gccgcctgcg aagtttttca
    21841 gatccatcac aataccggtg atattgcggt cgtccttcgc ctggcgaatg gtgttgacga
    21901 tatcaaacag tgagttttcc tgaagacgat cggaactggc accaagcagc tggcggctta
    21961 atttactaaa ccgctgagaa ctgtcgggtt tatcgacgat cacaccagaa atgtccagca
    22021 gcagtgcgcc acgactggcc gtttctttcg aatcaccacc actgacctgc atccagatcc
    22081 ccacaccaac cagcacgaga aaaataaaga acaggttaag taccatttca cggacgaaat
    22141 tcagcagacg ccacgtccat ttaaaaaatc cggcaataaa tcgccaaagg gttcgcatgt
    22201 attctcccaa cttaaggtca cacctgtttc aggcgcaata gatgtggtta tcgtaatgac
    22261 ccaaccggca cttgtcagca ggaattgcgg actgggctgt aacaaaatcc actctcgtgt
    22321 taattttgtg aataaatatc atgacaggag ttaatcaaat ggatgcactc gaactattga
    22381 tcaatcgccg tagcgcctcc cgcctggctg aacccgcgcc aacgggtgaa caactgcaaa
    22441 acatcctgcg tgcgggtatg cgtgcgccgg accataagtc catgcaaccg tggcatttct
    22501 ttgtgattga aggggaaggg cgcgagcgtt tcagcgccgt actggagcag ggggcgattg
    22561 ctgccggtag tgataacaaa gcaatcgaca aagcgcgtaa tgcgccgttc cgcgcaccgc
    22621 tcatcataac ggtggtggcg aaatgtgaag aaaatcataa agtcccgcgc tgggaacagg
    22681 aaatgtctgc gggatgcgcg gtcatggcga tgcaaatggc agcagttgcc caggggtttg
    22741 gcggcatctg gcgcagtggt gcattaactg aaagtccggt agtgcgtgaa gcattcggtt
    22801 gccgtgagca ggataaaatt gtcggttttc tctacctcgg tacgccgcag ttgaaagcat
    22861 ctacgtcgat aaacgtcccg gacccgacgc cgtttgtgac ttatttctga taattgtcgc
    22921 gaaactgtct ggattgtgag caaaggcgca ggaattcaga cactctcact tatcacttca
    22981 tggaatgagg gttaccatac ccggattgca ttgacaggag atgtccatga gcgagaactc
    23041 gattcgtttg acccaataca gccacggcgc tggttgcggc tgtaaaattt ccccaaaagt
    23101 gttggaaacc atcctgcaca gtgagcaggc gaagtttgtt gatccgaatt tgcttgtggg
    23161 taatgaaacc cgcgacgatg cggcggtgta cgatctgggc aatggcacca gcgttatcag
    23221 taccaccgac ttctttatgc cgatcgttga taatcctttc gattttggcc gcattgcggc
    23281 gactaacgcc atcagcgata tctttgctat gggcggcaaa ccgattatgg cgattgcgat
    23341 cctcggctgg ccgattaaca aactttcccc ggaaattgcc cgcgaagtga ccgaaggtgg
    23401 acgctatgca tgccgtcagg cgggtattgc gctggctggc ggtcactcca tcgatgcgcc
    23461 ggagccgatt tttggtctgg cggtaacggg gatcgtaccg accgagcggg tgaagaaaaa
    23521 cagtaccgca caagccggat gcaaactgtt cctgacgaaa ccgctgggga ttggcgttct
    23581 taccacggct gagaaaaaat cactgctgaa accagaacat cagggactgg cgacggaagt
    23641 gatgtgccgg atgaacatcg caggcgtgtc ctttgccaac atcgaaggcg taaaagcgat
    23701 gaccgacgtt acgggttttg gtttactggg gcatttaagc gaaatgtgtc agggcgcagg
    23761 tgtgcaggcg cgcgtcgact atgacgcgat cccgaaattg ccgggggttg aagagtacat
    23821 taagttgggc gcagtgcctg gcggcaccga acgtaacttt gccagctacg gtcatctgat
    23881 gggtgaaatg ccgcgtgaag tgcgcgatct gctgtgcgat ccgcaaactt ctggcggttt
    23941 gctgctggcg gtcatgccgg aagcagaaaa tgaggtcaaa gctacagccg ccgagtttgg
    24001 cattgaactg acggcgattg gcgaactggt gccagcgcgc ggcggtcgtg ccatggttga
    24061 gatccgttaa ttcaatgcgg ttgtttattg ccgaaaaacc gagtctggcg cgcgccattg
    24121 ctgatgtcct gcctaaaccg caccggaaag gcgatggctt tatcgagtgc ggtaatggtc
    24181 aggtggtgac ctggtgtatc ggtcacctgc ttgagcaggc gcagccagac gcctacgaca
    24241 gccgctatgc gcgctggaat cttgcggatt tgccaattgt cccggaaaag tggcaattac
    24301 agccccgacc ctccgtgact aaacaactta atgtcatcaa acgcttcctg catgaagcca
    24361 gcgaaatcgt tcacgccgga gacccggatc gcgaagggca actgctggtg gatgaagtgc
    24421 tggactacct gcaactggca ccggaaaagc gccagcaggt acagcgttgt ttgataaacg
    24481 acttgaaccc gcaggcggtt gagcgggcga tcgatcgtct tcgctccaat agcgagtttg
    24541 taccgctgtg cgtttctgca ctggcgcggg cgcgggctga ctggctgtac ggcattaata
    24601 tgacccgtgc gtataccatt ctcggccgca atgccggtta tcagggtgtg ctttccgtgg
    24661 gacgcgtgca gacgcccgta ctcggactgg tggtgcgccg cgacgaagag attgaaaact
    24721 tcgtggcgaa agacttcttt gaagtcaaag cacatatcgt gacacctgcc gatgagcggt
    24781 ttaccgctat ctggcaaccg agcgaagcgt gtgaaccgta ccaggatgaa gaagggcgct
    24841 tgttacatcg tccactggcg gagcatgtgg ttaaccgtat tagtggtcaa ccagctattg
    24901 tcaccagcta taacgataaa cgggaatcag aatccgcgcc gctgcctttt tcgctttcgg
    24961 cgttgcagat tgaagcggct aaacgttttg gtctgagcgc gcagaacgtg cttgatatct
    25021 gccagaagct gtacgaaacg tacaagctaa tcacttatcc gcgttccgat tgccgctatt
    25081 tgccagaaga acattttgcc ggacgccacg cggtgatgaa tgctatcagc gttcatgcac
    25141 cggatctgtt gccgcagcca gtggtagatc cagatatacg caaccgctgt tgggatgaca
    25201 aaaaggtcga tgcgcaccac gccatcattc cgaccgcacg gagttctgcg atcaacctga
    25261 cggagaacga agcgaaggtc tataacctga ttgcccgtca gtacttgatg cagttctgcc
    25321 cggatgcggt gttccgcaag tgtgttatcg aactggacat tgccaaaggc aaatttgtcg
    25381 ctaaagcccg ttttcttgct gaagcaggct ggcgcacgct gttaggcagc aaagagcgcg
    25441 atgaagaaaa cgacggcacg ccgctgcctg tggtggcgaa aggcgatgaa ttgttgtgcg
    25501 aaaaaggcga agtggtagag cggcaaaccc agccgccgcg ccattttacc gatgcaacac
    25561 tgctttcggc gatgaccggg atcgcgcgct ttgtgcagga caaagatctg aaaaagatcc
    25621 ttcgtgcgac cgatggtctg gggacagaag caacgcgtgc cgggattatt gaactgttgt
    25681 tcaagcgggg tttcctgacc aaaaaagggc gctatatcca ctccaccgac gccggaaaag
    25741 cgctattcca ttcgctgcca gaaatggcga cgcgaccgga catgaccgcg cactgggaat
    25801 cggtgctgac gcaaatcagc gaaaagcagt gtcgctatca ggactttatg cagccgctgg
    25861 tggggacatt gtaccagttg attgatcagg caaagcgcac gtcggtaagg cagtttcggg
    25921 gaataatggc tcccggcggt ggagaaggga agaaaaagga ttcgccacgc aagagagcgc
    25981 cgaaaaaaag cccgccatca gaagaggcgg gcaatggagt gataatataa aggttctttc
    26041 aaccatctga tactgaagat ttttatggcc ggataaggcg tttgcgctgt atccggcaca
    26101 attgtcttaa atcacgccct ggcttaacat cgcatccgca accttcacaa aaccggcaat
    26161 gttcgcgccc tgcacgtagt tggtttgctc accttcacca ccatgctcaa cacaggcatg
    26221 gtggatatcc agcatgatgt gatgcaaacg tgcgtcaact ttctcggctt tccagcccag
    26281 gcgcgcagcg ttttgcgcca tttccaggcc cgatgttgct acaccgccag cattagccgc
    26341 tttacccggt gcaaacagta cgcctgcctg ctggaacagt tcagtcgctt cgatggtggt
    26401 cggcatattt gccccttcgg cgacggcttt aacgccattg gcgataagct gatgcgcggc
    26461 gtcaacatcc agttcgttct gggtggcgca aggcagggcg atatcaaccg gtacagacca
    26521 cggttgttgg ccttcgagat agaccagacc aaattctttg gcgtaatctg ccactcgacc
    26581 atcgcggctg gctttgattt cgataaggcg cgccagtttc tctttcgtga atccgctttc
    26641 atcaactaca gtgccgctgg agtctgacgc agtgatcact cgagcaccaa attccatcgc
    26701 tttttcgata gcgtactggg cgacgttgcc ggagccagaa acggaaacgc gcatcccttc
    26761 aaaacccata ccgtggcgtt ttagcattgc ttctgtgaaa taaaccagac cgtagccggt
    26821 agcttccggg cgaataagac tgccgccaaa tgaaaggccc ttaccggtga agacgcaggc
    26881 ggtattgttg gagagctttt tcatcatccc cgccataaag ccgacttcac gaccaccaac
    26941 gccgatatca cctgccggaa cgtcagtatc cgcgcccagg tggcgataca gttcagtcat
    27001 cagcgcctgg cagaaacgca taacttcgcc ttcgcttttc cctttcggat caaagtcgct
    27061 gccgccttta ccaccaccca tcggcagagt agtcagggca tttttaaagg tttgctcgaa
    27121 gccgaggaat ttgagaatgg aaaggtttac tgaagggtgg aagcgcatac cgcctttgta
    27181 cggaccgatg gcggagctga attgcacacg ccatgcacgg ttgacctgca cctggttgcg
    27241 atcatcaacc catactacgc gaaattggat cacgcgctcc ggttcaacca gacgctccag
    27301 taatgacatc tgacgatatt tgggattttg ttcaagaaaa ggccagagtg tggtcattac
    27361 ttcacgaacg gcttgcgcga actcggtttg attcgggtcg cgcttttgga catggttgag
    27421 gaatgactcc agagaatatg tctgatccat agatataaaa cccttatata ttaatacgat
    27481 tatgcttatg ttgtttatgt catgtgcttt tgcagttttc gactatacca tcaagaatgt
    27541 gacggtaagc aagaaaaaaa tgacccagga aagcaaatta ataacgagag taatctcata
    27601 accaaatgcg ataactcaga cgctaaagtt ttgccgcccg gctaccgtta tctgtagaag
    27661 agacaataac gttaaggagt tccctgtgag tcgagcattg atcgccgtag tattagcatt
    27721 tccattaatt acactggcta acccgcatta tcatccggac gtggaggtaa acgtaccgcc
    27781 agaagtgttc agttcaggcg ggcagtcagc gcagccctgt actcagtgct gcgtttatca
    27841 ggatcaaaat tattctgaag gggcagtaat taaagccgaa ggaatactgc tgcaatgcca
    27901 acgggatgac aaaaccctaa gcactaatcc gctggtctgg cggcgcgtga agccataaac
    27961 gcctctaata atggaatgtc agcaggggcc agcggatatc gcagcgcctc ttcaggtgag
    28021 caccagacca gcgcctgatg ttcatgtgcc tgtaacgtcc cgtggaagtc gggtacgtgc
    28081 caggcatgaa gatggataat ccgccccgaa acttctcgct gatggctggc aacatagtca
    28141 ccaacagttg cttcgatgcc cagttcttcg tttaactcac gcaccagcgc ctgccgctgg
    28201 ctttcatccg gctcgatttt accaccggca aactcccata atcccgcctg atcgctctgg
    28261 gcagggcgtt gcgcgagtaa aattttgcca tcacgttcga tgatggcggc aacaacttca
    28321 atcattttca taaattacac acgggcagat aagcgaaaaa tgccataata tccgcactgt
    28381 tgctcaatca gaaaggcttt atatttaagg agtgcctgtg ctagaccgcc atcttcatcc
    28441 ccggattaaa ccgttgttgc atcagtgcgt gcgggttctt gataaaccgg gcattacgcc
    28501 agatggttta acattagtgg gatttgccat cggcgtgctg gcactgcctt ttctggcgct
    28561 gggctggtat ctggcggcac tagtcgccat tttgttgaac aggctgcttg atggtctgga
    28621 cggtgcgctg gcgcggcgca gagggcttac cgacgcgggc ggctttctcg atatttctct
    28681 cgattttctt ttttacgcgc tggtgccttt tgggtttatc ctcgccgcac cggagcaaaa
    28741 cgccctggca ggcggctggc tgctgtttgc gtttatcggc acgggcagca gttttctcgc
    28801 ttttgctgcg ctggcggcga aacatcagat tgataatcct ggttatgcgc ataaatcgtt
    28861 ttattatctg ggcggcttaa ccgaaggcag cgagacgatt ttgctgtttg ttctgagttg
    28921 cctctttccg gcctgttttc cgtggtttgc gtgggtattt ggtgcgttgt gctggatgac
    28981 gacctttacg cgggtgtgga gtgggtatct gacgctgaag tcgctccagc gtcagtaatt
    29041 gcaatgttat ttactgctgt ccgggccgcg ttcaccggtt gctaccggat tttttggatc
    29101 gctgctccat tcgtaccagc caccgtcgta aacggagacg ttattccagc ccattgcgcg
    29161 tgcgtacata aaggtttctg acgcgcgcca gccagtgccg cagtagaatg aaacttgctg
    29221 atctggtttg atattccatg ctttccacat agcggttata tcatcggcgc tgcgcatggt
    29281 gccatccggg ttatggaaat cttccatatg cgtcgagtcg ctacctgcgt gtccccaacg
    29341 tgctccggct atttcacctt ttggtttaat atagctgtaa ccgctggtcg taccgataaa
    29401 ttctggccac gaacgaatgc tcaccagcga tgcatcctgg cgatgcagca gtccacgcgc
    29461 ttgttccata tcaagcatca gttgcggttg tgccgggatc ttcacgccga aatccggttc
    29521 cgctttcact ttcggtggcg taccgcgctc aacgggcaga cccgcgtcgg accaggtttg
    29581 ccagcctccg tccagcaggc gcacatcttt cacgccggca taaagcataa tttgcgccac
    29641 acgcgctgca gcgtatacgt cacgcccgta cagaatgacc gtggtgtcat ggcgaatgcc
    29701 gtgttttgcc agcatcgctt tcagttgttc atcagaaact ttgttccaca gcggttcgct
    29761 ttccacttcg ttggtgtcga tgtagtcagc gccgggaata tggctgataa ggtaaaattt
    29821 tggagcgccc caggccgctt caatgacttt ccagtcaccg gcaggtttcg ccgtaacctc
    29881 tttaccttgt tgcaggtcat gcagccactg cggatatacc agctgttcaa agtgcggcag
    29941 tttttgcaga cgggaaggtt cgcttagcgc gtcactcagg atggagatat gcgtaaaacc
    30001 tgctttttgc agtcgcgttt tgacggcgtc gacatctttg tcattaccgt acagtgccac
    30061 cggggcatcg gctttcaggt tatgttgctt gatccactcg ttgagctgtt cggtgctcat
    30121 tttgtcgagc cagctagcag agaggtttaa ggcggcaggt tcatgaccgg aagggccatt
    30181 taaggtttgt ggccagccgt tataaaacgc gctggggcga gtatctatcg ctttgccatt
    30241 ttgttgttga agctggtcaa gtgtaagagg cttcgccagt tcagcggccc acgaagaagc
    30301 gcaagccagc cctaaagcca ttgccagcgc ggtcatttga gaaacacgtt tcatcgaaaa
    30361 tcccgacatt gtagttttga gagcgccatt ctgaactgac gcatcgggaa aaactttgcg
    30421 ttatcgcagt ttgttgtaat tttctgacca ctgcgccata tccagaacgg ggctatcagg
    30481 aggaacatcc tgaagatcgt gcgtcacctg cacaacaggg atcgccatgg cgcgaatttc
    30541 gctgaacacc caatggcgaa aattatcgcg cagggccaca tcaagacggc tgaatggctc
    30601 atccagtagc aacgcttttg gctgagcgag aagggcgcga agcagagcaa cgcgcgctcg
    30661 ctgaccgcca gacaaagtgg caggatcctg atggaacgct ccgtcaaggc ctgaacgctc
    30721 aagtgcatca ttcacggcat tacgtcgggc attcccctta agtgtcgccg gtagcgccag
    30781 cagtaaattt tgcccgacgc tgaactggtc aaataacagt gcatcctgga aaagaatgcc
    30841 aatctgacgc tgtgcggtgg gtagcatgtc aatccgttgc tcattaagcc atagctcccc
    30901 tgtacaagaa aactgtccgg ccagcgcacc aatcatccac gaaaacagag tggatttccc
    30961 gcagccggat ggtcccatta acgtgacaat gtcaccttta tctactgtaa agttaacgtt
    31021 tgtcagcaag cggctttctg gtaaacgtag cgaaacattt ttcacgcaga gcattagcgg
    31081 agtccttgtc tgacataacc tacccatttt acgactaacg cggtcagggc aaaaataata
    31141 agcggtaaca gcagttgcca taaagcctgg gcggcgagaa taccgttgct gccgccgctg
    31201 cttaatgcca ccgcttcagt ggtgagcgtc ggaaaacgcc ccgcgcccag ccacagcgtc
    31261 ggcatatact gcgcaatact gactgaaaat cccaccgcga aggcaatcag cgcagggcgc
    31321 aacatgagtg ggcattttac gtaaaagaag attttggccc gcgaccagcc cagtgtttgc
    31381 gcaatcaaaa ttaaccgtga atcaatgcgc tgccaggcgg gttgcaggat aaacagcatc
    31441 cacggcatta cccacagcag atgcccccag accaccgccg tccagcttcc atccaggttc
    31501 agccatagcg ccagcgtgta ctggcccgcc accagcggca gagcgggtaa taaaatgggc
    31561 aaccatagcc acaactggcg acgctgtggc ccccattcca gccacagcag taacaagagc
    31621 aaagcgatga atgccgccac cagccccatt gtcaggctgt tgatgagcgc ttgactattg
    31681 atcgtcgact gatccgcgag gatcgccagc agaaccacac acagcacacc ggttaagggt
    31741 aaaaaactcg ccagcgtatt gcttggcaat aaaggcgtgg caggcttacg aacgccatct
    31801 acgcggggaa tagtacgccg ccagccacgc catagcagat agcccagcaa aacgtaggcg
    31861 gcgagtaaca gcatcagcag caggctggcg agtgcgcctt tcgtttgttg atcggcgtcg
    31921 ccctgagtta accactgcca gctaattacc gccagcgtcg ggggattacc tggcccaaga
    31981 ataatcgcca catccacgac cgacagcgac caggcgacaa tcgccagcat cgccattgct
    32041 aacgcagacg cgacggaggg caacagcagc cagttcaggc attgccagcg gctgtagccc
    32101 agcgaatcca gcacaatgag ttgctgcaac agccgttttt cgctcaatac tgccgctaag
    32161 atccacagca gaaatgcgct ttctttcacc gccagggtga ggcccagccc aatacccaat
    32221 ttgtccattg gcggagtgaa atacgggaaa tagtcataaa gcagccctcc gtcagcaaag
    32281 agcagaaggg cgctggtggc aaaagccaca tggggaatgg cgagcagcca cggcagacgg
    32341 gcgcacatac gctgccattt cggccctggc cacaacgcca caatcaccag cagggcaatc
    32401 aacaacgccc cgaccgccgc aatggttgtc gacaccagcg tcgccagtaa tgcctgcggt
    32461 aactgtggat cggcaaataa cgcctgccag tgcgtcaacg acaaagcagg cgatatcagc
    32521 gtgagagctg ccgggatcag cggtgcataa atcaccgcta tcatcgccca cagcaaaaag
    32581 attaatgcgt accgtaacgg tgtagccatt cttgttccag cgcatttacc caacctgcgt
    32641 gcggttcagc cagtaccggc ggcagatcct gcggcattct cgattgcaat gtttcgcgct
    32701 gcccgtcagg cagtttttgc gggtcgagaa cagaaggatc gccccagaca gcaggatctg
    32761 ctttacgcag ttgcgcatcg ggtgagagca ggaaattggc aactaccttc gccgcagcac
    32821 tggcattcgc gttggcagga atggtgacga aatggacgtt gccaatcatc ccctcgcgaa
    32881 aaccaaaact gtaactgctt gcaggcaaat cgccgctggc gattttttgc tgcgcatgcg
    32941 cggggttaaa ggtcagcgac aggcgcaatg tgttagcttt cagcagagca tccatccgcg
    33001 cgggcgaagg cgggaaatcc tttccttcgc gccacaaata cggatgcagt gcatcaagat
    33061 attgccacaa gggcgcagtg acgcgggcga aagtggcatc gtccggcgct tcttttaatg
    33121 ctgtgggatc tggcgttagc ataatcagca actgttcaag aaacgccgtg ccggtaaagt
    33181 ccggtgggcg cggataggta accgtgccgg gattggcttt agcaaactcc agtaaggctt
    33241 gcggcgtttg tggtggctgt agcgtaacat cgcggcgggc gataaacgtc agttgtgcgc
    33301 cgccccaggg cgattcagcc ccttctgtag gcactgaaaa atcttcccgc accggaagct
    33361 gtgtgtcgac atagcgccag ttgggcagag tctccgccca gccggtttgt aataaattgg
    33421 cctcttttaa ggtgcggaag ttttcgccgt tcacccagag cagatccacc gaaccgcccg
    33481 ttttacgtcc ggcagcaact tcggtctgaa tgcgtttcac cgcgtctgcg gcatccgcga
    33541 gacgaacaat cttcaggttt atagcgtaat gggttttcat ctcgccgcta acccagtcga
    33601 gatagcggtt aattgcggta tcgccgcccc aggcgttaaa ccagacggtt tgtcctttgg
    33661 cctcattttt tatttcctgc cagtcactgg catgtgttgc caaagaaaac agcgataaca
    33721 atcccagcaa ccacccacaa tggcgcatct tctctcctta agaacgtttt tcaggaatac
    33781 ggcacagccc ctgagcggga atgtccatgg cagaattaaa acgggctgac agattttgca
    33841 ggcctatcaa tgccgtcagt tcggtgagcg cctgagcgtc aaaatgcgta gccagtcggg
    33901 cgcgcagagc atcatcgacc gttggcggcg ttacgcttgc ggcttcggcg tactccagcg
    33961 ccagccgttc ttcatcgcta aagagcgggc tttgccgcca gtcagccact gccagcagtt
    34021 tatcggtgct gccggtacgc tcggcgactt tcatactggt gatatccacg caaaactcac
    34081 acaggcacat ttgcgcaatg cgcgcgctga caagcgatcg tactaccgga tcgagcggtg
    34141 agcgtttgcg ctccagccag ccgacaaaca tcgacaccag ataaaagata aacgggatcc
    34201 gcccccacca gcgaatcggg cttagcacct cgccgtaatg gcgacgatgc agccacgcct
    34261 gcggacgtaa aatgaaagga attttgctaa gcggcggtaa acccatcagg cattcctctt
    34321 ctggcgctca agccatattt tcttcgccat aaaaatcacc acggtcaggg caaacagaat
    34381 aaacagtccg gtgacaaacc agaaagtacc gcctgttaac atgctgcccg cccaggaata
    34441 aacaatagtc gccggtaatt gaccaagccc ggtggcgata aaaaacgagc gaaaacgtat
    34501 tgaagtcaaa ccggcagcat agctgattgg atcgaaaggg acaaaaggca ataaccgaca
    34561 taccaggatg gtgtgtttgc cgtagcgagt gaaaaagccg tccatactgt caagtacggt
    34621 tttgccggtt aatttttcca ccacttcgcg gcccatcact ctggcgataa aaaagcacag
    34681 cgccgcgccg gccatcgaac tggtccacga cagtaagccg ccccagaacg cgccaaacag
    34741 cgacgcattg gcaaaggtga tcaaaaacgc aggtagcggt gcagcaatgg cctgtaaaat
    34801 catcaacaag aacgagacaa ctgccgctag tgcgccgtaa gactgaataa agcgttctat
    34861 accctgttgg tccacggcgg caaacgccgc aacgctgcga ttgataaact catggacgcc
    34921 gggaagcagc gcccatgcca gcagcacagc gaacaacagg atgatgaggg ttatacggta
    34981 gtaccagatt ttacgcgatt gcatcttcat catcctttat cctgctttat tcggtgattt
    35041 taaaggtaac cgttgccagc gtgttatccg ccgggagaac tgaggcattg cctttgaatt
    35101 tcacttcgcc gcgtttttcc accgcaccat aagtgtatgt tgcattgctg acgatgccga
    35161 ccgggcagct atccagacac accaggcaac ccgttttctt ctcttctgct gccgttaaat
    35221 taccgccaaa gcgcatgtcc agtttcttgc cattactgtc aacaatcact tcatcgaagg
    35281 aatacgcttt tgccgcccct tgccagttga ccgaaatatc cagtttgctg cctgtgacat
    35341 gagtcgtttc tttattatcc attgtcatgt tttcgcccgg cgtaccacct gcctctttca
    35401 gggcttcata aaatgctttc ggggtcgcat aacccataaa cagcgattta tgtccgttgg
    35461 agccatcttt aaacacaata ccgtgacgag tgtcgtcggt gaggaaacga ccattaattt
    35521 gcaccagcat ggttaccgta tggttattgg catcgacacg cagcggttgg ctgttcgaaa
    35581 gtccgtcgta ttccactttt gcagccgcat tctctttttg atcgcagccg ctaagcccag
    35641 caacagccag taagcagagt gcagccagtc cttttttcca tgacactgaa taatgttgca
    35701 acatcgttct atccttcatt ttttgggtga gaaagtgggc tgcggcgaga agcagacaga
    35761 tccacatgtt tgtgtcgggc gtagagtttt gcgagctgga cgagaataaa cagtgccagg
    35821 cccgccagac agagttgtaa aataaagcgc agcgtaatgc cttcattggc gagatcgctt
    35881 gccatcacgg tataaataac aataccgggt agggtcgtga gtgccgaaat aagggtataa
    35941 ggccagaagg cgattgtggt taatccgtaa gcgtaatttt gaatattgta aggaaacaac
    36001 gggattaagc gggtcagaat aagaaaatca ataccgttac gcgcaatgcc tttttcaatg
    36061 gcctgaaagg tatggctatg gccaacgtat ttcagcagta aatcacgtcc cagccagcgc
    36121 gccagaagga atgagcacga ggaggccagc gtggcggcaa ttaatgatag tagtgtccct
    36181 aagagcgggc caaaaactat tcctcccgcg atcaccagta tgcttcctgg taacagaaag
    36241 agggtggcaa tgatgaataa cagaatatag aggctatagc cgaacaatcc gctctggcga
    36301 atgagtgtct gtaagtgggg taaatcggtg agcagatcga ataaaccgaa agcgtggata
    36361 gcgtaaatga ccagcgcaaa aataagacag gcaaaaagaa atttacgctc agcgttcatc
    36421 gtggagtttc ctatatcaaa cttgataata gagaagtggt cagacaacta aaaacgcagt
    36481 gacggtataa caaaggacgg cgggcaacaa atcattactg acagtttgtt gatttttctc
    36541 aaggttaatt ctcctgaccc agtttgagcc aggagatcag ctaaattagc ggcggaaggt
    36601 cgcccagacg ggggcgtgat cggacggttt ttccatgctg cgaatttcat agtcgatgcc
    36661 ggtttctacg caacattctg ccagcggttg gctggcgagc agcaggtcga tgcgcagacc
    36721 gcgattatcg tcaaaacctt ttgagcggta atcaaaccat gagaaacgat ctgctgtttg
    36781 cggattcgca tggcggaagg tatcgaccaa cccccagctc atcagcctct ccatccattc
    36841 gcgttcctcc ggaaggaaag aacattttcc ggtacgcagc cagcgcttac ggttctcttc
    36901 gccaatgcca atatccaggt cgccaggact gatattcata tcgcccataa tcagcaccgg
    36961 attttcacgc ttgagttcgg tttccaggta gttttgcaga ttctgataaa actgcgcctt
    37021 tgccgggaat tttatcggat ggtcgcggct ttcaccctgc gggaagtaac cgttgatcac
    37081 ggtgatattg cccagcggcg aggggatttc cgccataata atccgccgtt gcgcctcttc
    37141 gtcgtcaccg ggaaagccgc gacgcacgga aatcggcgtc tctttggtca gcagcgccac
    37201 gccataatgg cctttctgcc cgtgataaaa cacgttgtag ccgagcttcg ccacctcttc
    37261 gagcggaaac atatcgtcat gaacttttgt ctcctgcagg ccaatcacat ccggttggtg
    37321 cttttcgacg atggcttcaa gctggtgagg tctggcgcgc aggccgttga tattaaaaga
    37381 gacaaatttc atagtcgctg ccatttattc agataaagag tgcgtggatg gtagcagaat
    37441 ttcgctttgc ttaccgcctg ttgttaagtg atttgatcga tggttgttaa tgatgtcaac
    37501 gatggcgcaa aaaatgcccg cttttggtgc gcgttgcgtc agaatggcgc agtaatttcc
    37561 agtaaatttc gtcaatgatc acaattccag aattatattt tacttctgca taacattgcg
    37621 ttttttattc tttttattca cccacatcgc aaacgtattc actttatatg cactttaaat
    37681 gcatatgatg tggttataac tgcttgattt ccagttagcc tccgccgttt atgcactttt
    37741 atcact
//
LOCUS       DAFGPF010000040        37676 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFGPF010000040 DAFGPF010000000
VERSION     DAFGPF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37676
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.040"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            50..772
                     /gene="mngR"
                     /locus_tag="LSX49_002232"
     CDS             50..772
                     /gene="mngR"
                     /locus_tag="LSX49_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-D-glycerate transport/metabolism system
                     transcriptional repressor MngR"
                     /protein_id="HBL7168634.1"
                     /translation="MGHKPLYRQIADRIREQITCGELKPGDALPTESALQTEFGVSRV
                     TVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVETHSEVLIF
                     EVIPADNFLQQQLQISEQDRVWHVKRVRYRKQKPVALEETWMPLALFPDLTWQVMENS
                     KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGQVFEY
                     SRNAFNTDDYKFTLIAQRKSPR"
     gene            complement(876..1745)
                     /gene="sucD"
                     /locus_tag="LSX49_002233"
     CDS             complement(876..1745)
                     /gene="sucD"
                     /locus_tag="LSX49_002233"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HBL7168635.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(1745..2911)
                     /gene="sucC"
                     /locus_tag="LSX49_002234"
     CDS             complement(1745..2911)
                     /gene="sucC"
                     /locus_tag="LSX49_002234"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HBL7168636.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            complement(3005..4222)
                     /gene="odhB"
                     /locus_tag="LSX49_002235"
     CDS             complement(3005..4222)
                     /gene="odhB"
                     /locus_tag="LSX49_002235"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HBL7168637.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDVVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            complement(4237..7038)
                     /gene="sucA"
                     /locus_tag="LSX49_002236"
     CDS             complement(4237..7038)
                     /gene="sucA"
                     /locus_tag="LSX49_002236"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HBL7168638.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAISEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            complement(7400..8116)
                     /gene="sdhB"
                     /locus_tag="LSX49_002237"
     CDS             complement(7400..8116)
                     /gene="sdhB"
                     /locus_tag="LSX49_002237"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HBL7168639.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            complement(8132..9898)
                     /gene="sdhA"
                     /locus_tag="LSX49_002238"
     CDS             complement(8132..9898)
                     /gene="sdhA"
                     /locus_tag="LSX49_002238"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HBL7168640.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            complement(9898..10245)
                     /gene="sdhD"
                     /locus_tag="LSX49_002239"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             complement(9898..10245)
                     /gene="sdhD"
                     /locus_tag="LSX49_002239"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HBL7168641.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            complement(10239..10643)
                     /gene="sdhC"
                     /locus_tag="LSX49_002240"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             complement(10239..10643)
                     /gene="sdhC"
                     /locus_tag="LSX49_002240"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HBL7168642.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPVTAIASILHRVSGVITFV
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            11024..11131
                     /locus_tag="LSX49_002241"
     CDS             11024..11131
                     /locus_tag="LSX49_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168643.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            11337..12620
                     /gene="gltA"
                     /locus_tag="LSX49_002242"
     CDS             11337..12620
                     /gene="gltA"
                     /locus_tag="LSX49_002242"
                     /EC_number="2.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HBL7168644.1"
                     /translation="MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYAQRDFKSDIKK"
     gene            complement(12667..13977)
                     /locus_tag="LSX49_002243"
     CDS             complement(12667..13977)
                     /locus_tag="LSX49_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000126139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBL7168645.1"
                     /translation="MTALSELLAGSWLDNWLMIIPLMFVCLFINMPVWLAMFCGILTY
                     FLCYSNVPLMVAIQRLIATTQTPSLLAIPFFILLGTLMSYTGIAARILQIANVLIGRM
                     RGGLGGANILVSTMMGGVSASNLADAAMLSRMMVPEMEQKGYSRGFAAAITASGSLIT
                     PIIPPGIALILYGLVADVSIGSMFMAGILPGLLCSAMLIVTVWLVAIRRGLKPSSEHW
                     PKPKEVSVALVQAWPALFLIVAVIGGIRANIFTPTEAGAVAVLLVMFIGFVIYRELKI
                     SHVFTALSETARSTASVMLIIMASAALGWIFSLERAGITVAEFVTSLTDNKYVFLLII
                     NLLLLVLGMFLEGSAILLILVPLLKPVVAHFGIDPVHFGIIMILNLSLGTLSPPVGTV
                     MLLVCNTVQVSVGQFMREAVPLLISLILLLLVITYIPAISLLLV"
     gene            complement(13977..14438)
                     /locus_tag="LSX49_002244"
     CDS             complement(13977..14438)
                     /locus_tag="LSX49_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL7168646.1"
                     /translation="MRLLGKMIEVAAVLTLFILVIMTIAAVIMRYCFHMPLQWTEEVS
                     GLLMIWVVMFGAVVAERDNTHLSIPFLADALTSRGQRILAFLVSLMSIILLVVMAWSA
                     WKLAAGTAFKTTQILKISWFWIDIAVTVGAIGVACFTALQLIKKTPRKEGE"
     gene            complement(14498..15466)
                     /locus_tag="LSX49_002245"
     CDS             complement(14498..15466)
                     /locus_tag="LSX49_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate TRAP transporter
                     substrate-binding protein"
                     /protein_id="HBL7168647.1"
                     /translation="MKKLLTPLLFLLALFSPMLNAAPVTIKIAYESNPGEPADTVVKH
                     WAELVKKKSNGDIVFELYPSSQLGSKQDITEQALMGMNIITISDVGFLTDYDADLGIL
                     FGPYLTEDPQKLFAIYASDWFKQKEQKLREKGVHIVMSNYLYGTRQIIAKKPIRTPED
                     LKGMKIRVPNNVMQIKAIEAMGATPTPMPLGDVYPALTQGMIDGVENPVSVLYGQKLH
                     EQAKYLSMVNYLTNTSLWLGGEAFFSTLTPAQLDIIHQTAYEAGLYSQKITTEQDATM
                     LKTMQEQGVEIIYPDVAPFKEKALKVYQQFPEWTPGLYDTIQQQLK"
     gene            complement(15494..16690)
                     /locus_tag="LSX49_002246"
     CDS             complement(15494..16690)
                     /locus_tag="LSX49_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBL7168648.1"
                     /translation="MEGYVRQNGRPGIRNTVQVIFMVECASHVAKKIAEGFPCHDVQY
                     FGFSGCYPSDYGYRLVKNLATHSNVGGVLIISLGCENFDRRRLEQEVRESGRPCHTLV
                     IQENKGTTNTITLGKQLVAEMLEQLADTPRCILNWSDLVVGTICGGSDGTSGITGNPA
                     VGRAFDQLLEKGATCIFEESGELLGCEQHMMSRAASSQARDAIEVAMTKAERYYSLMG
                     LGSFSNGNAEGGLTTQEEKSLGAYTKSGDALIAGVILPTQQTPFPGLWLMDVVPDGEP
                     RFGYPNINDSSEALELIASGCHMVLFTTGRGSVIGSVIAPIIKVCNNPQTWEHLSDDM
                     DVNAGRVISEGATLDDIADDIMQVIEHVANGQYCAAERLEHQEFVLTYKAFDYSKSAV
                     CRADPR"
     gene            complement(16690..17001)
                     /locus_tag="LSX49_002247"
     CDS             complement(16690..17001)
                     /locus_tag="LSX49_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002432396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBL7168649.1"
                     /translation="MRKRALKLHAKDNCVVALNDIASGDIVWWDEGEMVACSSVTLGH
                     KLACEALNNGDSILKYGAIIGHATRDIAMGEHVHSHNLASNAIAIFHHDDAGYQSEEK
                     A"
     gene            complement(17016..17771)
                     /locus_tag="LSX49_002248"
     CDS             complement(17016..17771)
                     /locus_tag="LSX49_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7168650.1"
                     /translation="MNAFSLHNKTALITGAASGLGLAMAKCMIVSGAKVIIADLNGEL
                     AQATAGTLGSQASWIQMDVGDTAAAQEKVDVLISEHGAIDILVNNAGNHCKKPIEEMS
                     VSDFESVLDVHVVGAFALTKALVPHMKQRGKGCVLFTASMTSFLGQPLVTGYSAAKSA
                     YLGMIRGMTTELAVHGIRVNGIAPGWIDTPMLRKAIEGDDERRNKILGRTPMKKFGKP
                     EDIGWAAVYLASDAAAFVSGQVLVVDGGALIGF"
     gene            complement(17783..18796)
                     /locus_tag="LSX49_002249"
     CDS             complement(17783..18796)
                     /locus_tag="LSX49_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL7168651.1"
                     /translation="MKALTIEQGSQARFVDIPEPVCGKGEVLINVERVGLCGSDLNTW
                     RGLNPLVNYPCIPGHEIGGTVLATGDMAGAIKPGDRVVVLPCTECGVCSSCLSGRPNA
                     CKNNQTLGVQRQGGMAQQLTMPAHKVIVCNALSVDELALVEPLAVGLHAARRAQINVG
                     EWVAVIGCGVIGLGAIAAASAMGARVIAIDIDDRKRNIALECGAQRFLNSQQCDVAAE
                     LVLLNDGRGPEVVIEAVGNQQTIEQATGLVAFSGRVVYVGYAKQPVSYQSAQFLMKEL
                     DIRGSRNATVADFRAVLALMESGRYPVSNLVSAHYPLEQADHAFSDWASDPGAYTKIL
                     IDL"
     gene            complement(18809..19495)
                     /locus_tag="LSX49_002250"
     CDS             complement(18809..19495)
                     /locus_tag="LSX49_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RraA family protein"
                     /protein_id="HBL7168652.1"
                     /translation="MWKSDNELFALMKTRLFTAVVGDILDTLGYMHQFVSPAIKPLDV
                     NTVVAGRAMPVLESDVYETKSTSGKTAIGEKPFGIMFEALDALKENDVYITTGSSLRY
                     ALWGGLMSTRAMHLKAAGAVLDGYARDSAEILELKFPTFCHGTYAQDQGPRGKVIDFG
                     VPIEFHGVRVNPGDIVFGDRDGLLIIPQVVEKEVITQALEKVATESEVRKAISDGMST
                     VQAFETFGVM"
     gene            19759..20472
                     /locus_tag="LSX49_002251"
     CDS             19759..20472
                     /locus_tag="LSX49_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBL7168653.1"
                     /translation="MSESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEVQLIQK
                     LGVSRGIVREAYRSLAALGILETHSGKVPRIKKFDDEVLRVVFGFALATEQVTTEQIL
                     QVRRWLELGVVEAAARNGEEEDFANLRAEMAKIREQFNDVESFITHDIRFHQLLAVAS
                     KNPLFMMLLQALHQQLRQSIQEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATQ
                     AMKSHFDSPVSALINNSSS"
     gene            20652..21698
                     /locus_tag="LSX49_002252"
     CDS             20652..21698
                     /locus_tag="LSX49_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL7168654.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLALHLPAALLLGPMIAGIIFSMHG
                     VTLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQQIVWFPPVSINLLLTILLAVVAGTAGCLLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIIAMQTLRLFSILLTGPA
                     IARFISTYAPKHSA"
     gene            complement(21695..22486)
                     /gene="nei"
                     /locus_tag="LSX49_002253"
     CDS             complement(21695..22486)
                     /gene="nei"
                     /locus_tag="LSX49_002253"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HBL7168655.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKSYQSRLIGQH
                     VTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAPQLDALAHALLDIPRLSYATRGQVDE
                     NKYHGALFRFKVFHRDGEPCERCGGIIEKTTLSSRPFYWCPGCQH"
     gene            complement(22522..23256)
                     /gene="pxpA"
                     /locus_tag="LSX49_002254"
     CDS             complement(22522..23256)
                     /gene="pxpA"
                     /locus_tag="LSX49_002254"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HBL7168656.1"
                     /translation="MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETIFAQTLYQIGALAAITRAQGGVMCH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGERYGLVTREEVF
                     ADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWAMVTAQTVCLH
                     GDGEHALAFARRLRATFAEKGIVVAA"
     gene            complement(23246..24178)
                     /gene="pxpC"
                     /locus_tag="LSX49_002255"
     CDS             complement(23246..24178)
                     /gene="pxpC"
                     /locus_tag="LSX49_002255"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HBL7168657.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLRDGDRLPIGKAKRDFM
                     EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSPQSNRMGYRLQGQILKR
                     TTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            complement(24172..24828)
                     /gene="pxpB"
                     /locus_tag="LSX49_002256"
     CDS             complement(24172..24828)
                     /gene="pxpB"
                     /locus_tag="LSX49_002256"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBL7168658.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EAIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAAGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLHVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPACDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            complement(24851..25594)
                     /gene="ybgI"
                     /locus_tag="LSX49_002257"
     CDS             complement(24851..25594)
                     /gene="ybgI"
                     /locus_tag="LSX49_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HBL7168659.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKEMVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            25865..27346
                     /gene="dtpD"
                     /locus_tag="LSX49_002258"
     CDS             25865..27346
                     /gene="dtpD"
                     /locus_tag="LSX49_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HBL7168660.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYSD
                     NHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGF
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITVLFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES"
     gene            complement(27388..28806)
                     /gene="phrB"
                     /locus_tag="LSX49_002259"
     CDS             complement(27388..28806)
                     /gene="phrB"
                     /locus_tag="LSX49_002259"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HBL7168661.1"
                     /translation="MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWAA
                     HNVSPRQAELINTQLNALQNALAEKGIPLLFREVDDFAASVEIVKQVCAENRVTHLFY
                     NYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGAIDPAPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQN
                     GAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLSEL
                     IWREFYRHLMTYYPSLCKHRPFIAWTDRVQWQSNPAHLKAWQEGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPTTQGEKFDREGEFIRQWLPELRDVPGKAVHEPWKWAEKTGVTLDYPQP
                     IVDHKEARLRTLAAYEEARKGA"
     gene            complement(28803..29312)
                     /locus_tag="LSX49_002260"
     CDS             complement(28803..29312)
                     /locus_tag="LSX49_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HBL7168662.1"
                     /translation="MNQQLFDDSTLIRIFALHELHNLKDRGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHRWQSLDDYYNQYRQRVIVLLSHPANRRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRRGEQSLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHAGVL"
     gene            complement(29413..29619)
                     /locus_tag="LSX49_002261"
     CDS             complement(29413..29619)
                     /locus_tag="LSX49_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HBL7168663.1"
                     /translation="MELYKEYPAWLIFLRRTCAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMDQAEKATGDFY"
     gene            29932..30021
                     /gene="kdpF"
                     /locus_tag="LSX49_002262"
     CDS             29932..30021
                     /gene="kdpF"
                     /locus_tag="LSX49_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBL7168664.1"
                     /translation="MSAGVITGVLLVFLLLGYLVYALINAEAF"
     gene            30021..31694
                     /gene="kdpA"
                     /locus_tag="LSX49_002263"
     CDS             30021..31694
                     /gene="kdpA"
                     /locus_tag="LSX49_002263"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBL7168665.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVER
                     VLFSALGVSDREMNWKQYLSAILGLNILGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGD
                     RRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLALCMFVGRFGVIIPVMAIAGSLV
                     SKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            31717..33765
                     /gene="kdpB"
                     /locus_tag="LSX49_002264"
     CDS             31717..33765
                     /gene="kdpB"
                     /locus_tag="LSX49_002264"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBL7168666.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTCISIAMASGVMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAVADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            33774..34346
                     /gene="kdpC"
                     /locus_tag="LSX49_002265"
     CDS             33774..34346
                     /gene="kdpC"
                     /locus_tag="LSX49_002265"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBL7168667.1"
                     /translation="MSGLRPALSTFLFLLLITGGVYPLLTTALGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPVLDKQIAARV
                     AALRAANPDASTSVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVNYIGQPVVNVVELNLALDKLDE"
     gene            34339..37023
                     /gene="kdpD"
                     /locus_tag="LSX49_002266"
     CDS             34339..37023
                     /gene="kdpD"
                     /locus_tag="LSX49_002266"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HBL7168668.1"
                     /translation="MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPLKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDSRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSSQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGINAHIEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM"
     gene            37020..>37676
                     /gene="kdpE"
                     /locus_tag="LSX49_002267"
     CDS             37020..>37676
                     /gene="kdpE"
                     /locus_tag="LSX49_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HBL7168669.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETG
                     I"
BASE COUNT         8785 a        10229 c         9573 g         9089 t
ORIGIN      
        1 tgaatttatc gagcataatg gctaaattcg tattaatgag atactagaaa tgggacacaa
       61 acccttatac cggcagattg ccgatcgcat tcgtgagcag attacgtgcg gcgagctaaa
      121 acctggcgat gcgttaccca ctgaatcggc attacaaaca gagtttggcg tcagccgggt
      181 tacggtgcgc caggctttgc gccagttagt cgagcagcag atcctcgaaa gcatccaggg
      241 cagcgggact tacgtcaaag aagagcgggt caattacgat atttttcagt taaccagttt
      301 tgatgaaaaa ctgtcggacc gtcacgtcga aacacatagt gaagtcctga tatttgaagt
      361 aattccggct gacaattttc ttcagcagca gctgcaaatt agcgagcagg atcgtgtgtg
      421 gcatgtgaag cgcgtgcgct atcgcaagca aaagccggtg gcgctggaag aaacctggat
      481 gccgcttgca ttattcccgg atctcacctg gcaggtcatg gaaaattcga aatatcactt
      541 tattgaagaa gtgaagaaga tggttatcga tcgtagcgaa caggagataa ttcccctgat
      601 gcccacggaa gagatgagcc gtctgcttaa tatcagccag actaagccga ttcttgaaaa
      661 agtatcgcgt ggatatttag ttgatggcca ggtgtttgaa tatagccgca acgcttttaa
      721 tactgatgac tataaattta ccctgatagc gcagcgaaaa tcgccgcgat aagcataaaa
      781 aaggccatca taagatggcc aaccatgtcg aaaccgacag cccttcgccc ttcctgtagg
      841 gggaagcggc gagggctatt tcttattaca gatatttatt tcagaacagt tttcagtgct
      901 tcaccgatat cagccaggct gcgaacggtt ttcacgcctg cggcttccag agcagcgaat
      961 ttctcatccg cagtaccttt accaccggca atgatggcac ccgcgtggcc catacgtttg
     1021 cctttcggcg cagtcacacc agcgatgtaa cccacaactg gcttggtgac gtgctctttg
     1081 atgtacgcag ccgcttcttc ttcagcgcta ccgccgatct caccgatcat cacgatcgct
     1141 tcagtctgcg gatctttttc gaacatttcg agaatatcga taaagttaga gccagggatc
     1201 gggtcgccgc cgataccaac acaggtcgac tgaccgaaac cgtaatccgt ggtctgttta
     1261 accgcttcat aggtcagcgt accggaacgg gaaacgatac ccactttacc tggtttgtga
     1321 atgtgacccg gctggatacc gattttgcat tcccccgggg tgataacgcc tgggcagttc
     1381 gggccgatca tacgaacgcc tgcttcatcc agtttcactt tcaccgtcag catatccagc
     1441 gtcgggatgc cttcagtgat ggtgataatc agtttgatgc ctgcatcgat agcttccaga
     1501 atggagtctt tgcagaacgg tgctggtacg tagataacag aggcggtagc gccagtggca
     1561 gcaacagctt cacgcacggt gttaaacacc ggcaggccga ggtgggtagt accgccttta
     1621 cctggggtta cgccgccaac cattttagtg ccgtatgcaa tggcctgttc agagtggaaa
     1681 gtcccctggc taccagtaaa gccctggcag ataaccttgg tgtttttatc aattaaaatg
     1741 gacattattt cccctccact gcggcaacaa cctgctgagc tgcatccgtc agaccttttg
     1801 ctgcaataat attcaggccg ctgtcagcca gtttcttcgc accgagttcg gcgttgttac
     1861 cttccagacg taccacgacc ggtacgttaa cacccacttc tgctaccgcg ccgatgatac
     1921 cgtcagcgat caggtcgcaa cgaacgatac cgccgaagat gttaaccaga acggctttca
     1981 ctttgtcgtc agagaggatg attttgaacg cttcggttac acgttctttg gttgcgccac
     2041 cgccaacgtc caggaagtta gccggttcgc cgccgtgcag tttaacgatg tccatcgtac
     2101 ccatcgccag acctgcgccg ttaaccatac aaccgatgtt accgtccagc gcaacgtagt
     2161 tcagttccca ctgtgcagcc tgtgcttcac gcggatcttc ctgcgactgg tcacgcattt
     2221 cacgcagatc aggctggcgg aacagtgcgt tgccatcagc gcccagtttg ccgtcgaggc
     2281 aaatcagatc gccctgtttg gtaataacca gcgggttgat ttcgataagc gcaaggtcgc
     2341 gctccaggaa aatggtcgcc aggcccatga agattttggt gaactgctga accagtttac
     2401 cttccagacc cagtttaaac gccagctcgc gtccctgata cggcatcggg ccagtcagcg
     2461 gatcaagcgc aactttgtgg atcaggtgcg gagtttcttc cgccactttt tcgatttcca
     2521 cgccgccttc ggtggaggcc ataaagacca cgcgacggga actacggtca acaacggcac
     2581 cgagatacag ctctttagcg atatcggtcg ctgcttcaac cagaatctgg ttaaccggtt
     2641 ggccattggc atctgtttga tacgttacca gacgcttgcc cagccagttt tctgcaaaag
     2701 cacggatgtc ttctttgctg tttacaactt tcacaccgcc cgctttaccg cggccaccag
     2761 cgtgaacctg acatttcact acccacggac cggcaccgat ttttgaagcg gcttcttctg
     2821 cttcgcgtgg agtagtacag gcataaccca ccggtgctgg taagccatag cgggcaaaaa
     2881 gttgttttgc ctgatattca tgtaagttca tgtgttctgt ccatccttca gtaatcgtta
     2941 tcttttaaac cgtagaccga ccccctatcc acgtcggtct acagtgcagg tgaagcttaa
     3001 actactacac gtccagcagc agacgcgtcg gatcttccag caactctttg atcgttacca
     3061 ggaagcccac ggattcgcga ccatcgatca aacggtgatc gtaggacagc gccaggtaca
     3121 tcatcggcag gatctcaacc tggccattca ccgccatcgg acgatctttg atagcgtgca
     3181 tacccagaat tgcgctctgc ggcgggttga tgataggcgt agacatcagg gaaccgaaca
     3241 caccaccgtt ggtgatggta aagttaccac cagtcagatc ttcaaccgtc agcttgccgt
     3301 cacggccttt aactgccagc tctttaattt tcttctcgat gtctgccatg ccgagggtat
     3361 cgacatcacg cagaaccggc gtcaccaggc cgcgcggcgt agaaaccgcc atactgacgt
     3421 cgaaatagtt gtggtagacc acatcatcgc cgtcgataga cgcattcact tccgggtaac
     3481 gtttcagggc ttcaaccacc gctttcacgt agaaggacat aaagcccaga cggatgccgt
     3541 ggcgtttttc aaacgcttca ccgtactgct tacgcagatc cataatcggc ttcatgttga
     3601 cttcgttgaa cgtggtcagc atggcggtgg agtttttcgc ttccagcaga cgctctgcca
     3661 cacgcttacg caggcgagtc atcggcacac gtttttcgct acgtgcagcc agggccggtt
     3721 gcgccgccgg agcagccgct gccggagcag actctttcgc cggggctttc gccagatgtt
     3781 tttccacatc ttcacgggtc agacgaccac ccacacccgt gcctttaatg gcgctggcgt
     3841 cgaggttatg ttcagccagc aggcgacgga tcgccgggct taacgcatcg ttgttttgct
     3901 cttccagaga cgcctgctgg cgttgcgccg gagtggacgc tttctcttca gatttggcgc
     3961 tggtttcttt accggcgctg ttgccttcac gcaggcgacc aaggatctga cgagacgtta
     4021 cggttgtacc ttcatcttcc agaaccgcat ccagaatgcc gtctgctgat gccggtactt
     4081 ccagtaccac tttgtcagtt tcgatttcta ccagcacttc atcacgtacg actacgtcgc
     4141 cgggtttttt atgccaggtt gcgacggtgg catcggctac ggattcaggc aggtcaggga
     4201 ccagaatatc tacgctactc attgtgtatc ctttatttat tcgacgttca gcgcgtcatt
     4261 aaccagatct tgttgctgtt tctggtgaac ggacatatac cctaccgccg gagaggcgga
     4321 ggccgggcgg cctgcataac gcagagaagc cccaaacgga atcacttcac ggaaatgatg
     4381 ctggctgcag taccatgcgc cctggttgag cggctcttcc tggcaccaga caaaatcctt
     4441 gacgtgagca aactgctgca acacttcctg catcgcttta tgcgggaacg ggtagagttg
     4501 ctcgatacgc acaatggcga catcgtgttg attgttctta cgacgttgtt ccagcagatc
     4561 gtaataaacc ttaccagaac acatcactac gcgcttcacg cccttcggat caagctcgtc
     4621 gatttcactg atggctggca ggaaggtgcc gttcgccagt tcttcgaggc tggaaaccgc
     4681 cagcggatga cgcagcaggg atttcggcga catcacgacc agtggacgac gcatcccgcg
     4741 caacgcctga cgacgcagca tgtggtaaac ctgtgccggg gtagaaggta cgcaaacctg
     4801 catgttttgc tcagcgcaaa gttgcagata acgttccaga cgcgcggagg agtgctccgg
     4861 cccctgccct tcgtaaccgt gcggcagcaa catcaccagg ccacacatcc ggccccattt
     4921 ctgttcgcca gaggagatga actggtcgat aaccacctgt gcaccgttgg cgaagtcacc
     4981 gaactgtgct tcccagatgg tcagggtgcg tggttctgcg gtggcataac cgtattcaaa
     5041 cgccagtacg gcttcttcag acagtacaga gtcccagacg cggaacgcgc cctggccgtt
     5101 atggatatgt tgcagcggcg tgtaagtgga accgttagac tggttgtgga tcaccgcgtg
     5161 gcggtggaag aaggtaccgc gaccggagtc ttcacccgac aggcgaaccg gaatgccttc
     5221 gtcaaccaac gtggcgtaag cgaggttttc cgcgccgccc cagtcgaaca gtttctcacc
     5281 ggctgccatc gcctggcgat cgccataaat tttggcaacg cgagactgca tttcaaccgc
     5341 ttccggcacc gtgctgatgc gtttagccag ttcctgcagg cgcttcatct caactttgtt
     5401 cgggtactct tcgtcccatt cgtggttgag gtacggcgac caggtgaaag agtgcatgtt
     5461 catcggacgc cactctgcta caacgcaatc gccagcatcc agcgcatcgc ggtacaggtt
     5521 aaccatctcg gtggcatctt ccagcgtcgc gactttttcc tgctccagct tgtcagcgta
     5581 gattttgcgc ggcgtcggat gttttttgat tttctgatac atcagcggct gggttgcgct
     5641 cggctcgtcg gcttcgttgt ggccgtgacg gcggtagcat accaggtcga tgaagacatc
     5701 acgtttaaag gtgttacgga aatcgagcgc cagacgggtc acaaaggcaa cggcttccgg
     5761 atcatccgca ttaacgtgga aaatcggtgc ctgaaccatc ttaccgatat cagtacagta
     5821 cggcgtcgaa cgggcatcca gcgggttaga ggtggtgaag ccaacctggt tgttgataac
     5881 gatacgtacc gtaccgccaa cttcataacc acgcgctttc gacatgttca gggtttcctg
     5941 aactacgccc tgcccggtca ctgcggcgtc accatgaatg gtgattggca gcactttgtt
     6001 gctgctcggc tcatcaagtc tgtccagacg ggcacgaaca gaaccgataa cgaccgggct
     6061 tacaatctca aggtgagacg ggttaaacgc cagcgccagg tgcaccaggc cgccatcggt
     6121 ctggaagtca gacgagaagc ccatgtggta tttcacgtcg cccgtgccga ggtgttcttt
     6181 atgtttaccg gcaaactcgt cgaacaagtc ttgcggtttt ttacccagca cgttcaccag
     6241 cacgttcaga cgaccacggt gcgccatccc gagaaccact tcgcgggtgc cgctgttgcc
     6301 agcgtggcgg atcatctctt taagcatcgg gattaacgcg tcaccgcctt ccagcgagaa
     6361 gcgttttgcg ccagggaatt ttgcgccaag gtaacgttca aggccttcag cggcggtcag
     6421 ttcgcttaag aagcgttttt tctcttcgct attgaaagtc gcgcgaccag actcgatacg
     6481 ctgttggatc cagcgttttt cttcggtgct ggtaatgtgc atatactcgg caccaatcgg
     6541 gccacagtag gtttgcttga gggcttccag cagctcgccg agtttcatgg tttctttgcc
     6601 gctggcaaat gaaccgacgt tgaaggtctc ctggaagtct gcttcggtca gatcgtggaa
     6661 agacggatcc agatcggcca ctttatcttg ctgccacagt cccagcggat cgagattcgc
     6721 atgctggtga ccacggaagc ggtatgcgtt aatgagctgc aggactttaa cctgcttcac
     6781 attggtgtca gggtcggaga tcgttgaaga gtaacgtgaa gcgtctttcg ccaggcggcg
     6841 gaaatattca cgcgtttgag agtggaattg atccggtttg actcccgtac caggtaactg
     6901 ctggaacgtc gaacgccagt tagcgtcaac cgagtcagga tcggttaaga agtcttcata
     6961 gagctgttct atccagctct ggtttgcgcc agagaggtaa gaagagtcca accaggcttt
     7021 caaagcgctg ttctgcatcg tgatccctta agcatctttt ttatgcttac ttcgccgtgg
     7081 atactaccac gcacatttca tatctgatgt gcgtgccggg gttcacttgt tgcggacttg
     7141 tcgtgttttc tgcgtccgct aaggaacctt taaaaactgt cttagtgtca ggggcagttt
     7201 ttaaagattt cctgcatttc ttttgtaggc cggataaggc attcacgccg catccggcgc
     7261 tgtttgcctg atgcgacgct tgcgcgtctt atcaggccta cggtttctgc atttcttttg
     7321 taggccggat aaggcgttca cgccgcatcc ggcactggtt gcctgatgcg acgcttgtgc
     7381 gtcttatcag gcctacggtt tacgcattac gttgcaacaa catcgacttg atatggccga
     7441 tggcgcgcgt cgggttcagc cccttcggac atacactgac gcagttcatg atgctgtgac
     7501 agcggaatac actgaatgca tcgctcaaac cgtcgaggcg gctgtcagtc tcggtatcac
     7561 ggctatcgat caggaaacga tatgccgcta acaagcctgc cggaccgata aacttatcgg
     7621 gattccacca gaaagacgga caagaggttg aacaacatgc gcagagaata cattcataca
     7681 acccgtcgag tttttcgcgc tgctctggca tctgtaaatg ctcgcgagct ggcggatttt
     7741 gtccattatt caacaggtaa ggcttaattt tctcatattg cgcatagaat tgtcccatgt
     7801 ctaccaccaa atcgcggatc accggtaaac ctggcagcgg acgaatcaca atcttcttgc
     7861 ccggctggtt gagtgccgaa atcggggtaa tacaggccag accattctta ccgttcatgt
     7921 tcagaccgtc ggaaccgcac acaccttcac ggcaggagcg gcggaacgac aggctgggat
     7981 ctttctcttt cagctgaata agcgcatcca gcagcatcat gtcgcgacct tcttccgctt
     8041 ccagggtgta atcctgcata cgcggagcat catcaacatc cgggttatag cgataaattg
     8101 aaaactcgag tctcattttc ctgtctccgc attagtaagt acgaatcttc ggcgggaatg
     8161 ccgggcgcag tttcggttcc atgttgacgc ttcggcgcgt catggattcc gactctggca
     8221 gatacaggga gtggcacagc cagttttcat catcacgatc cgggaagtcg aagcggctat
     8281 gcgcgccacg gctttcggta cggaagttgg cagaaacagc cgttgcatac gccgtttcca
     8341 tcaggttatc cagttccagg cactcaacgc gctgggtgtt gaactcgctg gaagtgtcat
     8401 ccagacgggc atttttcaga cgctcgcgga taactttcaa ctgctcaagc cctttcgcca
     8461 tcgcatcacc ttcacggaag accgagaagt tatgctgcat acattcttgc agtgctttac
     8521 ggatcgccac cggatcttca ccgttacggt tattgttcca gcggttcagg cgatccagag
     8581 acgcttctac atcagactcg ctggcatcgc gcagtgcgcc ctgctcggcg atagactctt
     8641 gcagatgcag acctgccgca cgaccaaata ccaccaggtc cagcagcgag ttgccgccca
     8701 gacggttagc gccgtgtacc gatacacaag cgatttcacc aacggcaaac agccccggaa
     8761 caaccacatc ttcgcctttc tcattcaccg tcagcgcctg accggtcact ttggtcggaa
     8821 taccgcccat catgtagtga caggttggga taaccggaat cggctctttc accggatcga
     8881 cgtgagcgaa ggtacgggag agttccagaa tacccggcag acgggattcg agaacttctt
     8941 tccccagatg gtcaagtttc agttttgcgt gtggccccca cggaccatca cagccgcgac
     9001 cttcacggat ttcgatcatg atggaacgcg ccaccacgtc acggcccgcc aggtctttgg
     9061 cgttcggcgc ataacgctcc ataaagcgtt cgccatgttt gttcagcaga taaccgcctt
     9121 caccacggca cccttcggtg accagtacgc ccgcaccggc aataccggtc gggtggaact
     9181 gccacatttc catatcctgc accggtacgc ctgcacggat agccatgccg acaccgtcgc
     9241 cagtgttaat gtgggcgttg gtggtggact gataaatacg ccctgccccg ccagtcgcca
     9301 gcactgtcgc gcgagcttta aagtaaacca cttcaccagt ttcgatgcac agtgcggtac
     9361 aaccgaccac tgcgccatcc tggtttttca ccagatccag cgcataccac tcggagaaaa
     9421 tggtggtgtg gtttttcagg ttctgctgat aaagcgtgtg caacagtgcg tgaccggtac
     9481 ggtcagctgc cgccgcagta cgtgccgcct gctcgccgcc gaagtttttc gactgaccgc
     9541 caaacggacg ttgatagata cgaccatcat caagacgcga gaacggcagg cccatatgtt
     9601 ccagttccag aatcgcttcc ggcccggttt tacacatata ttcaatcgcg tcctggtcac
     9661 cgatatagtc cgaccctttt acggtgtcgt acatatgcca ttcccagtta tcttcatggg
     9721 tattacccag cgcaacggta ataccacctt gcgcagaaac ggtatgggaa cgggtcggga
     9781 agaccttaga gagcagcgca caggtctggc cactctggga aatttgcagc gccgcgcgca
     9841 tacctgcgcc gccagcacca atcacaactg catcaaattc tctgactggc aatttcatca
     9901 cacaccccac accacaacga atccataaat cacgtaaacc accagtgcaa cgacaatcac
     9961 cagttgcagc atcaggcgca aggccagcgg tttaacgtag tcggtcaaca cctgccacat
    10021 gccgatccag gcatggatca agatagaaaa cagcgccagc agggtgaaca ctttggtgaa
    10081 cgcagaggcg aagaaaccaa tccagacttc atatgtcagc tcgccactgg tagcgaaaaa
    10141 accgaccata taaatgatgt agagcgtcag gacgatagcg gtagcacgaa cgaggatgaa
    10201 atcatgtacg ccattgcgtc ctaatgcgga ggcgttgctt accatacgag gactcctgcg
    10261 agaagtgaaa gcacgacagt aataacaaag gagattttgg cggagcgttt acccgcttcg
    10321 aatgtttctt ccagatagcc aaaatccatc atcatgtggc gaatacctac gacgacgtga
    10381 tatgccagag cggtaaggat gccccacatg ataaatttga cgaagaagct gcccataatc
    10441 gcggaagctt gctcgaaacc ttcaggggaa gagaggctgg tacccagaag ccacagcagg
    10501 atgcccactg caacaaaggt gatcacaccg gaaacgcgat ggagaatgga cgctatcgcc
    10561 gtgacgggga accggatggt ctgtaggtcc agattaacag gtctttgttt tttcacattt
    10621 cttatcatga ataacgccca catgctgttc ttattattcc ctggggacta cgggcacaga
    10681 ggttaacttt ctgttaccag gagacgtcgg gatttccttc ctccggtctg cttgcgggtc
    10741 agacagcgtc ctttctataa ctgcgcgtca tgcaaaacac tgcttccaga tgcgaaaacg
    10801 acacgttaca acgctgggtg gctcgggatt gcagggtgtt ccggagacct ggcggcagta
    10861 taggctgttc acaaaatcat tacaattaac ctacatatag tttgtcgggt tttatcccga
    10921 acagtgatct gcgtcacgat aacaacattt atttaatttt taatcatcta atttgacaat
    10981 cattcaacaa agttgttaca aacattacta ggaaaagcat ataatgcgta aaagttatga
    11041 agtcggtatt tcacctaaga ttaacttatg taacagtgtg gaagtattga ccaattcatt
    11101 cgggacagtt attagtggta gacaagttta ataattcgga ttgctaagta cttgattcgc
    11161 catttattcg tcatcaatag atcctttacc tgcaagcgcc cagagctctg tacccaggtt
    11221 ttcccctctt tcacagagcg gcgagccaaa taacaaacgg gtaaagccag gttgatgtgc
    11281 gaaggcaaat ttaagttccg gcagtcttac gcaataaggc gctaaggaga ccttaaatgg
    11341 ctgatacaaa agcaaaactc accctcaacg gggacacagc tgttgaactg gatgtgctga
    11401 aaggcacgct gggtcaagat gttattgata tccgtactct cggttcaaaa ggtgtgttca
    11461 cctttgaccc aggcttcact tcaaccgcat cctgcgaatc taaaattact tttattgatg
    11521 gtgatgaagg tattttgctg caccgcggtt tcccgatcga tcagctggcg accgattcta
    11581 actacctgga agtttgttac atcctgctga atggtgaaaa accgactcag gaacagtatg
    11641 acgaatttaa aactacggtg acccgtcata ccatgatcca cgagcagatt acccgtctgt
    11701 tccatgcttt ccgtcgcgac tcgcatccaa tggcagtcat gtgtggtatt accggcgcgc
    11761 tggcagcgtt ctatcacgac tcgctggatg ttaacaatcc tcgtcatcgt gaaattgccg
    11821 cgttccgcct gctgtcaaaa atgccgacca tggccgcgat gtgttacaag tattccattg
    11881 gtcagccatt tgtttacccg cgcaacgatc tctcctacgc cggtaacttc ctgaatatga
    11941 tgttctccac accgtgcgaa ccgtatgaag ttaatccgat tctggaacgt gctatggacc
    12001 gtattctgat cctgcacgct gaccatgaac agaacgcctc cacctccacc gtgcgtaccg
    12061 ctggctcttc gggtgcgaac ccgtttgcct gtatcgcagc aggtattgct tcactgtggg
    12121 gacctgcgca cggtggtgct aacgaagcgg cgctgaaaat gctggaagaa atcagctccg
    12181 ttaaacacat tccggaattt gttcgtcgtg cgaaagacaa aaatgattct ttccgcctga
    12241 tgggcttcgg tcatcgcgtg tacaaaaact acgacccgcg cgccaccgta atgcgtgaaa
    12301 cctgccatga agtgctgaaa gagctgggca ccaaagatga cctgctggaa gtggctatgg
    12361 agctggaaaa catcgcgctg aacgacccgt actttatcga gaaaaaactg tacccgaacg
    12421 tcgatttcta ctctggtatc atcctgaaag cgatgggtat tccgtcttct atgttcaccg
    12481 tgatcttcgc tatggcacgt acggttggct ggatcgccca ctggagcgaa atgcacagtg
    12541 acggtatgaa gattgcccgt ccgcgtcagc tgtataccgg ctacgcgcag cgtgatttta
    12601 agtcggatat taagaagtaa aaatgacacc gacaaaaccc tgcgtggaca cgcagggttt
    12661 ttaattctac accagcagca aagatattgc cggaatatag gtaatgacca acagaagtaa
    12721 aataagactg atcagtaatg gcaccgcttc acgcataaat tgcccgacag aaacctgtac
    12781 ggtattacat accagcagca tcaccgttcc gacaggtggt gataacgttc ctaacgataa
    12841 gttgaggatc ataatgatgc caaaatgcac cggatcaatg ccaaaatgag ccaccacggg
    12901 tttaagtaat gggactaata tcagcagaat ggcactacct tcaaggaaca tgccaagcac
    12961 cagcagcaat agattgataa tcaataaaaa gacgtattta ttatcggtca gagaagttac
    13021 aaactccgca accgtgatac ctgcccgctc aagggaaaat atccagccca gcgcggcact
    13081 cgccataatg attaacatga ccgatgccgt ggaacgcgcc gtctcagaga gtgctgtaaa
    13141 tacatggctg attttcagtt cgcgataaat tacaaaacca ataaacatta ccaataatac
    13201 tgctaccgct ccggcttccg ttggcgtaaa gatatttgcc cgaataccac cgataaccgc
    13261 aacaattaag aacagtgctg gccaggcctg caccagcgcc actgacactt ctttcggttt
    13321 tggccagtgt tcgctggaag gttttaaacc gcgacgaata gccaccaacc atacggtaac
    13381 gatcaacatg gcggagcaca gcagacctgg caggatcccg gccataaaca tggagccgat
    13441 ggagacatcc gccaccagtc cgtaaaggat cagtgcaata cccggtggaa taattggtgt
    13501 aatcagcgaa ccacttgccg ttatcgccgc cgcaaagcca cgggaataac ctttctgttc
    13561 catttccggc accatcatgc gcgataacat tgcggcatcc gccagatttg aggcactgac
    13621 accgcccatc atggtactga ccagaatatt agccccaccc aggccaccgc gcattctgcc
    13681 aatcaacacg ttggcaattt gcaaaatacg cgcggcaata ccggtatagc tcattaacgt
    13741 gcctaataag ataaaaaacg gaatagctaa cagcgaaggg gtttgcgtcg tggcaatcaa
    13801 acgctgaatt gccaccatta acggcacatt tgaatagcaa aggaagtagg tcagaatgcc
    13861 gcaaaacatc gccagccata ccggcatatt gataaataaa cagacgaaca taagcggaat
    13921 gatcatcagc cagttatcca gccagcttcc cgccagtaat tcactcaatg ctgtcattat
    13981 tcaccttctt tgcgtggcgt tttcttgatc agttgtaagg cagtaaaaca ggcgacaccg
    14041 atagcgccaa ccgtgacggc aatatcgatc caaaaccagg atatttttaa tatttgcgtg
    14101 gttttaaagg ctgtcccggc agctaatttc catgctgacc aggccatgac caccagcaaa
    14161 ataatagaca tcagagagac taaaaacgct aatatacgtt gcccgcgtga agtaagtgca
    14221 tcggctaaaa atggaatcga taaatgggta ttatctcgtt cagcaacaac cgcaccaaac
    14281 atgactaccc aaatcattaa taaaccggaa acctcttctg tccactgtaa tggcatatga
    14341 aaacagtaac gcattattac cgcagcaatg gtcatgatta ccaatataaa gagcgttaat
    14401 accgcagcaa cttcaatcat tttccctaaa agacgcataa acacctctgc tcttaacggt
    14461 cggtgccgaa acaccgacca gtccttatgc catgaagtta tttcagctgt tgctgaatag
    14521 tgtcatacaa accaggggtc cattccggga attgttgata gacttttaag gctttttctt
    14581 tgaaaggggc gacgtcagga tagatgattt ccacgccctg ctcctgcatg gttttcaaca
    14641 ttgtcgcatc ctgctcagtg gtaattttct ggctatataa accagcttca tacgctgtct
    14701 ggtgaataat atctaactgc gcaggtgtca gggtactgaa aaacgcttcg ccacccaacc
    14761 ataatgatgt attggtcaga tagttcacca ttgacagata tttcgcctgc tcatgcagct
    14821 tttgcccata gagaacagaa accgggtttt ccacaccatc gatcatcccc tgagtcagcg
    14881 ccggataaac atctcccagc ggcattggtg ttggggttgc gcccatcgct tcgatagctt
    14941 taatctgcat gacgttattc ggcacgcgga tcttcatccc tttcaagtct tcaggtgtac
    15001 gaatcggttt tttagcaatg atctgcctgg taccgtacag atagttgctc atgacaatat
    15061 gcacaccttt ttcccgtagt ttctgttctt tttgtttaaa ccagtcactg gcataaatcg
    15121 caaacagttt ctgcggatct tcggttaaat aaggcccaaa caatattccc aagtctgcat
    15181 cgtagtcagt taaaaatcct acatcactga tggtgataat attcatcccc atcaacgctt
    15241 gttcagtaat atcttgttta gaacctaact gtgaacttgg gtaaagttcg aaaacaatat
    15301 ctccattgct ttttttcttc acaagttctg cccagtgctt cactactgta tccgctggct
    15361 cgccggggtt actttcatag gcgattttga tagttaccgg tgcggcattc agcatcggac
    15421 taaataaagc taaaagaaat aaaagtggtg tcagtaattt tttcattatt attacctgta
    15481 agagctttat cgattaacgg ggatctgccc gacagactgc acttttgctg taatcaaatg
    15541 ctttatacgt taaaacaaac tcctgatgtt ccagtcgttc tgcggcacaa tattgaccgt
    15601 tggcgacatg ttcaatcacc tgcataatat cgtctgcaat atcgtcgagc gttgcgcctt
    15661 cgctaattac acgaccggca ttaacgtcca tatcgtcaga taaatgctcc cacgtctgcg
    15721 ggttattaca cactttaata ataggagcga tcactgaacc aataactgaa ccgcgacctg
    15781 tggtaaataa caccatatga cagccagagg cgataagttc cagtgcttct gaggaatcgt
    15841 taatattcgg atacccaaaa cgaggttcac catcaggcac cacgtccatc aaccaaagcc
    15901 caggaaaggg cgtttgttgc gtcggcaaaa taacgccagc aatcagcgca tcgcccgact
    15961 tggtataagc cccaagggat ttttcttcct gagtggttaa gccgccttca gcattaccgt
    16021 tagaaaaact ccccagcccc atcaaactgt aataacgttc ggcttttgtc attgccactt
    16081 cgatggcatc acgtgcctgc gaactagccg cgcgcgacat catatgctgc tcacaaccaa
    16141 gcaactcacc gctttcttca aaaatacagg tagccccttt ctccagcagt tggtcaaagg
    16201 cacgtcctac tgccgggtta cccgtgatac cactggtgcc atcggagcca ccgcagatag
    16261 taccaaccac caggtcgctc cagttcagga tacaacgcgg tgtatccgca agctgttcca
    16321 gcatttcagc gaccaactgc ttacccagag taatggtgtt ggtcgtgcct ttattttcct
    16381 gaatgaccag cgtatggcac ggtcgcccac tttctcgtac ttcttgctcc agccgacggc
    16441 gatcgaaatt ctcgcacccc agcgaaataa tcagtacacc acctacgttg ctatgagtcg
    16501 ccagattttt caccagccga tagccataat cgctgggata acaacctgaa aaaccaaaat
    16561 actgcacgtc gtgacaagga aatccttcgg caatcttttt agcgacatgg ctggcacact
    16621 ccaccataaa gattacctgc acagtattac gaatacctgg tcgaccattt tgccgtacat
    16681 aaccttccat tatgcttttt cctctgactg atagccggca tcatcatgat gaaaaatggc
    16741 gatggcattg ctggcaagat tatgggaatg cacatgttca cccatggcaa tatcgcgagt
    16801 ggcgtgtccg ataatggcgc cgtatttcag aatcgaatca ccattgttca gcgcttcgca
    16861 ggccagtttg tgccccaggg taacggaact acaggccacc atttccccct catcccacca
    16921 gacaatatcg ccactggcga tgtcattcag cgcgactaca cagttatctt tggcatgtag
    16981 ctttaacgca cgtttgcgca taattcctcc gtacatcaga agccgatcaa tgcgccgcca
    17041 tccaccacca gcacctgacc actgacaaac gccgctgcgt ctgaagccag ataaaccgca
    17101 gcccaaccga tatcctccgg cttgccgaat tttttcatcg gggtacgacc caggattttg
    17161 ttacggcgtt cgtcatcacc ttcaatggcc ttacgcaaca ttggtgtatc gatccagcct
    17221 ggcgcaatac cattgacgcg aatcccatga acggcaagct ccgtggtcat accgcgaatc
    17281 atgccgagat aggctgactt cgctgcgctg tagccagtaa ccagaggctg cccaagaaat
    17341 gaggtcatcg atgcagtaaa aagcacacag cctttaccgc gttgtttcat atgcggcacc
    17401 agcgctttgg ttaacgcaaa tgcgccgact acgtgaacgt cgagtactga ctcaaaatca
    17461 ctgacgctca tctcttcaat cggttttttg cagtgattgc ctgcgttatt gaccaggata
    17521 tcgatagccc cgtgttcgct aataagcaca tcaacttttt cctgcgcggc tgcggtatcc
    17581 ccgacatcca tttgtatcca actggcctgc gaccccaatg ttccggcggt cgcttgcgcc
    17641 agctcgccgt tcaggtcagc aataatgacc ttcgccccgc tgactatcat gcatttcgcc
    17701 attgccagcc ccagcccact ggctgcaccg gtgatcaacg cggttttgtt atgtaaagaa
    17761 aaagcattca tggtgtcgct ccttaaaggt caatgaggat tttggtatac gcgccgggat
    17821 cacttgccca gtcgctaaaa gcgtgatcag cctgttccag cgggtagtga gcactcacca
    17881 gattgctgac cggataacgc ccggactcca tcaatgccag cacggcacga aaatccgcca
    17941 cggtggcatt gcgcgaacca cggatatcca gttctttcat caggaactgc gcactctgat
    18001 aactcactgg ctgtttggcg taaccgacat aaaccacacg accgctaaac gccaccaacc
    18061 ctgtagcctg ttcaatggtt tgttgattac ccaccgcttc aatcaccact tccgggccgc
    18121 gaccgtcatt taacagcacc agttctgccg ccacgtcaca ttgctgcgaa ttaagaaaac
    18181 gttgcgcacc gcattccagg gcaatgttcc gcttgcgatc atcaatatcg atagcaatta
    18241 cgcgcgcccc catggcggat gccgcggcga tagcgccaag gccaattacc ccacaaccga
    18301 taactgcgac ccattcaccc acattaattt gcgcacgtct ggccgcatgt agtcccacgg
    18361 ccagcggttc taccagcgct aactcatcaa cacttaaggc attacagaca atgactttat
    18421 gtgcaggcat cgtcagttgt tgcgccatcc ccccctgacg ttgcacacca agagtttggt
    18481 tgtttttaca ggcgttagga cgaccgctca gacaggagct gcacacgcca cactcagtgc
    18541 aaggcagaac gaccacccgg tcacctggct tgatcgcccc tgccatatcg ccagttgcca
    18601 gcaccgtgcc gccaatttca tgccccggaa tacagggata attaaccagc ggatttagtc
    18661 cccgccaggt attgaggtca gaaccacaca gtccgacacg ctcaacattg attagcactt
    18721 ctcctttacc gcagacaggt tcggggatat caacaaatcg cgcctgactt ccctgctcaa
    18781 tggttaatgc cttcattcat tgctctcctt acattacgcc gaaggtttca aaggcctgta
    18841 ccgtgctcat gccatcactg atggctttgc gcacttcact ttcagttgcc actttttcca
    18901 gggcctgggt aataacttct ttctcaacaa cctggggaat aatcagtaat ccgtcacgat
    18961 caccaaacac gatatcgccc ggattcactc gcacgccgtg aaattcaata ggtacgccga
    19021 agtcgatgac cttgccgcgc ggaccttgat cctgtgcgta agtgccatga caaaaagtgg
    19081 gaaatttcaa ttcaagaatt tcagcagagt cacgggcgta accatcgagt accgcacctg
    19141 ctgctttcag atgcatggca cgggtagaca tcaacccgcc ccacaaggca tagcgcagag
    19201 agctgcccgt agtgatgtaa acatcgttct ctttgagggc atccagcgct tcaaacatga
    19261 tgccaaacgg tttttcgcca atcgccgtct tacccgacgt cgatttggtt tcgtaaacgt
    19321 ccgactccag caccggcatt gcccggcctg ccaccaccgt attcacatcc agcggcttga
    19381 ttgccggaga aacaaactgg tgcatatagc ccagcgtgtc gagaatatcg ccaaccacgg
    19441 cggtaaatag ccgggttttc atcaaagcaa aaagttcgtt atcactcttc cacattattt
    19501 tcgtcctgta agcctgttta acaggtttac agggtaagga gaaaaagcgc acaatactgc
    19561 gaagggcgtc acgaaaaagt tgtgtattta ctatttcttc gccactcttt cacacaatat
    19621 gtctttgatt cgcactgcat ggcgggcgca caggcgcagt agtctattga taatcaaggg
    19681 ttctggagga aaatatgaag gatacagtcc cggtattctg gatttcaccg accaggaaaa
    19741 agtacaacag gagtaaaaat gagtgagagt gcgttattga ccagcgtaac gttatcgtca
    19801 caggtcaaaa atcatattct taatctgatc gccgaacaaa aattgacacc ggggatgcca
    19861 gttcccagtg aagttcagct gattcagaaa ttgggtgtca gtcggggtat tgtgcgtgag
    19921 gcctatcgtt cacttgccgc cctggggatt ctggaaacgc acagcggtaa agtgccacga
    19981 atcaaaaaat ttgatgatga agtgctgcgc gtggtgtttg gatttgccct ggcgaccgaa
    20041 caagtgacaa cagagcaaat tcttcaagta cgccgctggc tggagttggg cgttgtggaa
    20101 gctgctgccc gtaatggcga agaggaagat tttgctaacc tacgggctga aatggcaaaa
    20161 atccgcgaac agttcaatga tgttgaaagc tttatcaccc atgatatccg cttccatcag
    20221 ttacttgccg ttgcctcaaa aaatccgctt tttatgatgt tattgcaggc attacatcag
    20281 cagttgcggc aatccatcca ggagggttta aacgcccaaa gcgatcagaa agagtatggc
    20341 aatcacatca tcacactaca ccagaaaatc tgcgatgctg tgtgtgccag ggatgtcgaa
    20401 acggcgactc aagccatgaa atcacacttc gacagcccgg tcagtgcact gatcaataat
    20461 tcctcgtcat aagacttatc tcagttcaat cgtttactct tccctctttt acaaacgaga
    20521 gggagacaac ggtacttaat acgcccttta gccaaaatct gtctttttct tgattaccgc
    20581 tattttttcg ttgaggcgca ttctttatgc tgtatcgata caccaaaggt aagttaaaca
    20641 gggagtgacg gatgccagtg ctacagtggg gaatgttatg tgttctgtca cttctccttt
    20701 ctattggctt cctcgcttta catctcccgg cggcactcct gcttggcccg atgatcgcgg
    20761 ggatcatctt cagtatgcac ggagtcactc tgcaacttcc ccgctccgct tttctcgctg
    20821 cccaagccat tcttggctgc atgattgcac aaaacctcac tggttcgatt ctcaccacgc
    20881 tggccgtcaa ctggccgatc gtgcttgcga ttttactggt gacgctgctt tccagcgcca
    20941 tcgtgggttg gttattggtg cgctatagct cactgcctgg gaataccggg gcctggggtt
    21001 cttctcctgg cggcgcggcg gcaatggtcg caatggcgca agattacggc gcagatattc
    21061 gcctggtggc gtttatgcaa tatctgcgag tgctgttcgt cgcaggagcc gctgttctgg
    21121 tcacccgcat gatgctgggc gataacgctg aagcggttaa ccagcagatc gtctggttcc
    21181 cgccagtgag cattaatctc ctgcttacga ttttgctcgc ggtcgttgcc ggtacggcgg
    21241 gatgcttgct acgtcttcct tccggcacga tgctcatccc gatgctggcg ggcgcagtgc
    21301 tccagtctgg tcagctcatc acgattgaac tcccggaatg gctgctggcg atggcatata
    21361 tggcaattgg ctggcggatt ggtcttggtt tcgataagca aatattactg cgggcattgc
    21421 gcccgctacc gcaaatcctg ctgtcgattt ttgctctgct ggctatttgt gcgggcatgg
    21481 cgtgggggct gacccggttt atgcatattg attttatgac cgcctacctc gccaccagcc
    21541 ccggcgggct tgataccgtg gcggtcatcg ccgcagggag caatgccgat atggcgctca
    21601 tcattgcgat gcaaaccctg cgcctgttca gtattttgct gacggggcct gccatcgcac
    21661 ggtttatttc aacctatgcg ccgaagcatt cggcctagtg ctggcagcct gggcaccagt
    21721 aaaacgggcg cgatgacagc gtggttttct caatgatgcc gccacagcgt tcgcaaggtt
    21781 cgccatcacg atgaaaaacc ttaaagcgaa acagcgcccc atgatatttg ttttcatcca
    21841 cctgcccccg cgtagcgtaa gaaagtcgcg gaatatccag taacgcgtgt gcgagtgcat
    21901 ccagttgcgg cgcattgaga tctttcgctt tatgatttcc ggtcaaccca acctgccaga
    21961 ggatctccac ccgcaaataa ttgccaagtc ctgccagaaa cgcctgatcg agcagtaatc
    22021 cagcaaactg acggttacga aagcgcggcg acaataatcg ttcctttacc acctccggcg
    22081 tcagattcgg atccagcaca tcgggaccaa cgcgttgtaa aaacggatgc gtggtcagtt
    22141 gttccggagt caacatctca atatccgagg cgctataaag cagaatggtt ttgtcagccg
    22201 tttgcagttt tacccgcaat actcgcgtgg tctgcggctc ttcgccggta tcaaccacgc
    22261 gccagacgcc gtaaagctga ttatggctgt agagcgttaa gtcgttggaa aaatgagtta
    22321 acaacgcctt accacgcgtt tccacatggg taacgtgttg accgataagt cgtgattgat
    22381 aagattttaa ctgcgggaag gcaaaccaga catcagttag tggtttgcct ttgatcgccg
    22441 cctccaggtt atccgctgca cggcggatct ccgggccttc aggcatggtg atatcctttt
    22501 ttcattcttt attaagcggg gttatgctgc gacaacaatc cccttttcag caaatgtagc
    22561 tcgtaatcgg cgggcgaacg ccagtgcgtg ctcgccatcg ccatgtaggc agaccgtttg
    22621 cgccgtgacc attgcccatt cgccggtgat acttttgact ctgccgtgtt gcaccatctc
    22681 caacgtttgc gccagcgcct gttcttcgtt ttcaatcaac gcgcctggct ggcttcgcgg
    22741 caccagcgaa ccgtctgcct gataaccacg atcggcaaac acttcctcgc gcgttaccag
    22801 gccatatcgt tcgcctgcac gaatcagctc gcttcctgcc agcccgacga gaatcaatgc
    22861 cggatcgcaa gcgtataccg ctctggcgat agcgtctgcc agttgtgcct ctttcgccgc
    22921 ctggttgtat aacatgccgt gcggtttgac atgacacatt acgccgcctt gcgcacgggt
    22981 aatcgctgcc agcgcgccaa tttgatacag cgtctgggcg aaaatggttt ctggcggcag
    23041 ctgcatggcg ctgcgaccaa aattttccct gtcgggaaaa ctcgggtgag cgccaatcgc
    23101 gacaccattt tttattgctt cacgcacgca agcctgcatg gtttgcgcat ctcctgcatg
    23161 aaatccacag gcaatattgg cagaggaaac cagcgttaat agctctgcgt cgctggcgca
    23221 gccttcgccc agatcggcgt tcaggtcaat tttcattgtg cagccgccac gctaattgtt
    23281 cgaaataacg ttgctgatct tgccgcgctt tcagtgcctc ttccagtgaa cactggacaa
    23341 aatgaatcgg ctgaccgagc ggaatttgcg ccagatggta catatcagcc tcaatgatac
    23401 aggcaatacg cgggtaacca ccggtggtct gtgcgtcgtt catcaataca atcggctggc
    23461 cgttatgcgg cacctgcacc acgcccggca acaaaccgtg agataacagt tcgcgatcgg
    23521 tggtgcgttt taaaatttgc ccctgtaagc gatagcccat gcggttactt tgcgggctaa
    23581 gctgccaggg cgaacgccag aatgcatcct gcgaggcgcg atcgaactca tgatattccg
    23641 gccccggcaa ggcgcgaatg cggttgcccc agagcagctg tttaacgccc tgcgcttcca
    23701 taaaatcacg cttcgctttg ccaatcggga gtcggtcacc atccctcagt aaacggcctt
    23761 ccagcccgcc aatccccact ttgagatcgg tgctgcatga tcccattacc ggcggaacat
    23821 caataccacc cgcgaccgcc agataactgc gcatcccgtg ctgcgggcgt ttaagcgtta
    23881 aacgctggcc tgctttcatc ggcaatcgcc agccggtcca gacggcatta tcatccagcc
    23941 gcgcttcgca accggcaccc gtcagagcaa accacccatc agtttcgaac tcaaccgtta
    24001 actgaccgag cgtgatctcc agcgcggggg cattggcgtc attacccacc agcaggttag
    24061 caatgcgtaa cgcaggcata tccagtgcgc cacagtggct gataccagac tgacgaaagc
    24121 cgtgacggcc gccatcctgc acggtggtgt acatgcccgc acgaataatc ttcagcatac
    24181 tccctccttc tgcggtacaa agcgcacgct gtctcccgga cgtaataaga tgggttcgtc
    24241 acacgccgga tcaaacaggc tgagtgaggt atgaccaatc aactgccagc cacccggcgt
    24301 tgccagcgga taaacaccgg tctgcggccc gccgatcccg acagaacctg ccggaacgtg
    24361 caagcgcggt tcagcgcgcc gtggcgtgtg tagttgttcc ggcaaactcc cgagatacgg
    24421 gaagcccggt tgaaaaccta aaaaccagac cacgtattcc acggaggagt gcaattcaac
    24481 aacctgtttt tcgctcaatc cacaatgcgc cgcgaccacc gccaaatccg gtccggctgc
    24541 gccaccgtaa actaccggaa tttcaataaa gcgagactcc ggctccagcg cctcactctc
    24601 ctcccaccag cgttgcaaac gctctatggc atccagcgcc agcgactcag gattacgcaa
    24661 aatcactgtg atattgttca tgccaggaat ggcttcaacc acattcggca tatccaccag
    24721 acgctgtgcc agtcgccaga tccgtttctg gctagccagc gtcaccggcg gttccagttc
    24781 cagtactacc gccgtttcac ctatcagata acaacgcgct cgttgcactt tcgatccctc
    24841 tgattattcg ttatgcagga ttaggaatat caataaaggt cacatcaaga tcggtatttt
    24901 cattcagcca ctcgctcaat gcgcgaatac caccgcgttc agtggcatgg tgacccgcag
    24961 cataaaaatg caatccctgc tcgcgggctg aatgaatggt ctgttcagaa acttcgccag
    25021 taataaaagc atccacgcca aaacgcgcgg cgctatcgat aaaactttgc ccaccccccg
    25081 tgcaccaagc gacgcgctgg accacctcag gtccggtatc gccacaccat aacggcttac
    25141 gtcccagacg cgcttcaatc caggaggcca gttccagtcc cggcacaggc atggtcagtt
    25201 cgccccacgg caccaacggc tcaatttcgc ccatgaccgt gatccccagt aacgccgcca
    25261 gctgtgcgtt attacccagc tccggatgcg cgtccagggg cagatgccag ccatacaggt
    25321 tgatatcatt cgccagcaac gtttttaaac ggttacgctt cattccgcga atgaccggag
    25381 attcaccttt ccagaagtag ccatgatgca caatgaccgc atccgcgccc agacgcactg
    25441 cctcatcgag caaagcctgg ctggcagtta caccggtaac aattttttgc accatctctt
    25501 tgccttccac ctgcaaacca ttcggcgcgt aatcactaat cgccgcgctg ttcagttttt
    25561 cgttaatcag ttgttccagt tcggtgtttt tcatcttcgc gccttccgta ttctgatagc
    25621 tacaccgtta acatagcgtt acctcgcctg ttcgtcgata gccaatcttt tgacatatta
    25681 agaaacaaac ccgacgccaa aagacgcaaa ttgtttatat catcacgctt cagctaatgt
    25741 atatttatgc aatcagacag catattgcat aaataatcag atctgtatca aagttttaac
    25801 tttaaggaaa cacaagcacg ccgcgcaact attacgtgac gttgcagtca attgtggaat
    25861 tattatgaat aaacacgcat cacaaccgcg cgctatttac tatgtcgttg cgctgcaaat
    25921 ctgggaatat tttagctttt acggcatgcg tgccctgctg atcctctatc tcaccaatca
    25981 actaaaatat agcgataatc acgcctacga gttatttagc gcctactgtt cgctggtata
    26041 tgtcacgcca atcctcggtg gctttttggc ggataaagtt ctcggcaatc gcatggcggt
    26101 gatgctgggg gcgttgttga tggcgatcgg tcatgtggtg ctgggtgcca gtgagatcca
    26161 tccgtcattc ctctatctgt ccctggcgat tatcgtctgc ggctatggtc tgtttaaatc
    26221 caacgtcagt tgcctgctcg gtgagctgta tgagccaacc gatccacgtc gtgatggcgg
    26281 tttctcgctg atgtatgcgg cgggtaacgt ggggtctatt atcgcaccta tcgcctgtgg
    26341 tttcgcccag gaagagtaca gttgggcgat gggctttggc ctggcagcgg tgggtatgat
    26401 cgcgggtctg gtcattttct tatgtggcaa tcgtcatttc acacataccc gcggcgttaa
    26461 caaaaaggta ctgcgtgcga caaactttct cctgcccaac tggggatggc tactggttct
    26521 gctggtggca acgcctgcgc tgattaccgt gttgttctgg aaagagtggt cggtatacgc
    26581 cttgattgtc gcgacgatca ttggccttgg ggttctggca aaaatttatc gcaaagcaga
    26641 aaaccaaaaa cagcgtaagg agctggggct gattgttacc ctcaccttct tcagcatgtt
    26701 gttctgggca ttcgcacaac aggggggtag ctcgattagc ctttatatcg accgcttcgt
    26761 taaccgcgat atgtttggtt ataccgttcc gactgctatg ttccagtcga ttaatgcctt
    26821 cgcagttatg ctgtgcggtg tgttcctggc gtgggtggtt aaagaaagcg tcgcaggtaa
    26881 tcgtaccgtg cgcatctggg gaaaatttgc tcttggcctt ggcctgatga gcgccggatt
    26941 ctgcattctg accttaagcg cccgctggtc cgcaatgtat ggtcactctt ctctgccact
    27001 gatggtgtta ggcctggcgg tgatgggctt tgcggaactg tttatcgacc cggttgctat
    27061 gtcgcagatt acgcgcattg aaatccccgg cgtgaccggc gtattaaccg gcatttatat
    27121 gctgctttcc ggcgcgattg cgaactatct ggcgggcgtg attgccgatc agacatcgca
    27181 ggcttcgttt gatgcttccg gggcgatcaa ctactccatc aatgcatata ttgaagtatt
    27241 tgatcaaatt acctggggcg cactggcgtg tgtaggactg gtactgatga tttggctgta
    27301 tcaggcgctt aagttcagaa accgcgcgct ggcgctggag tcttaataag ccagcaccat
    27361 gcctgataaa acgctcgctg cgttttatca ggctcctttc ctcgcttctt cgtacgctgc
    27421 cagcgttcgc agccttgcct ctttgtgatc gactatcggt tgcggataat ccaacgtcac
    27481 acctgttttc tctgcccact tccacggctc atgcaccgct ttccccggta catcgcgcag
    27541 ctccggtagc cactggcgga taaattcgcc ttcgcggtca aatttctcgc cctgagttgt
    27601 cgggttgaaa atacgaaaat acggcgctgc atcagtaccc gtagaagcgg cccactgcca
    27661 gccaccgtta ttagctgcca aatcaccatc aatcagctgc gacatgaaat atcgctcgcc
    27721 ttcgcgccag tcgatcaaca aatctttcac cagaaaactg gctgtaatca tccgtagccg
    27781 gttatgcatc cagccagtgc tgttaagctg acgcatggca gcatcgacaa tcgggtatcc
    27841 cgttttgcct tcctgccagg cctttaaatg ggcgggatta ctttgccact gtacacgatc
    27901 cgtccaggca ataaacggac gatgtttaca cagcgaagga taatacgtca tcaaatggcg
    27961 gtagaactcg cgccagatca gctcactaag ccagacacta ccggctccac cgtccagcgc
    28021 ctgcggctgt tccgccaaca agcgatgcaa acactggcga ggcgataacc cgcccgttgc
    28081 caggctggcg gacaaacgac tggtgccttc tactgccgga aaatctcgtt gttgctcata
    28141 ctctccggca ccgttctggc aaaactggcg taattgcgca atcgccgctt tttcttccac
    28201 cgggaaatgc gcagtatcga aagactgacg aggataattc agcgtaatgg atggcgcggg
    28261 atctatcgct ccactactac gtacttttgg cgcagcgacg cactccggca tcccttcccg
    28321 cagccgtttc agccaggcat tcttaaaagg cgtaaagact ttgtacatct catgattgcc
    28381 agtcatcacc gcccccggcg gcaggatcac gctgtcatca aatccttcac acaccacgtt
    28441 acgcagcgct ctttcaactt ccacatcccg cgcccgctca tttacctcat actgatagtt
    28501 ataaaaaaga tgagtaacgc ggttttccgc gcacacctgt ttaactattt cgacgctggc
    28561 ggcaaagtca tccacttcac ggaacaataa aggaatacct ttttccgcca gcgcgttttg
    28621 cagcgcatta agttgtgtat tgataagttc agcctgacgc ggcgacacat tatgcgccgc
    28681 ccactggcgt ggggtagcga tatacaacgc cagcacgcgt gcagacgaat tgcggcaggc
    28741 ggcagccagt gcgagattat cgtgcagacg taaatcctgg cgaaaccaga ccagatgggt
    28801 agtcataaaa ctcctgcatg gcgcaagtta atcacacgcg gccaaagttc gaaataacgc
    28861 tgccctgaaa gccaggcgtc aggataaagc gccatatagt gtttgatacg catcagcggc
    28921 gcaagaagcg attgctcgcc acggcgataa ctgtcgataa gcgccgccag ctgctggcgt
    28981 tctgtggaat caatatgtgg gcgaaaatat ccctgaacgt gcatcaaaac gttagtatga
    29041 tcacgccggt tggcagggtg agaaagcaaa acaatcacgc gttggcggta ctggttgtaa
    29101 tagtcatcca gactttgcca ccggtgaata tcagccacaa acgggccaag tttgcggtac
    29161 tccggctgag aatgcgccag aaagacgagt ttatagcggc tgtgataatc gagaagcgcc
    29221 ccgcgcgtta gtcctcgatc tttgagattg tgtaactcat gcaaagcaaa aatgcggata
    29281 agggtgctgt catcaaaaag ttgttgattc attactgctc ctgaacggtt tacaggagta
    29341 agtgtagacg ccgaaaaaag aaaaccgcca gcgtttccac cggcggtttt ctttaaacgt
    29401 catgtttggc aatcagtaaa aatcaccggt tgccttttcg gcctgatcca tccacaccgg
    29461 tttatcgctg gttttcgacc agacgcggtg caggtagcta taaaagcggg cgcggtcttt
    29521 ccagaaaagc atgaaaggca gcgccagaac gcccgctgca accgcacaag tacggcgtaa
    29581 aaagataagc catgcaggat attctttgta gagttccata cttttctccc ccttttgtat
    29641 ctacccggtg aatagcaccg gaaaaatgaa ttcgtttatc tgatgaaaat agtaccgctg
    29701 tttgtgtaat tttactactc atccgaccac ttatttttgc ttattgatgg tttatttata
    29761 ttcaccgtgt aattaagtta cataaaagtt aaattaatac taaacattag ttaaatcatt
    29821 gcttttgcca tttttatact ttttttacac cacgcccgca gatttttgcg aaatctttgc
    29881 agccagaact ctacccttcc ggtatcactt ttaggccact ggaggtgcac tgtgagtgca
    29941 ggcgtgataa ccggcgtgtt gctggtgttt ttattactgg gttatctggt ttatgccctg
    30001 atcaatgcgg aggcattctg atggctgcgc aagggttctt actgattgcc acgtttttac
    30061 tggtattaat ggtgctggcg cgtcccttag gtagcgggct ggcgcggctg attaatgata
    30121 ttcctcttcc tggtacgacg ggcgttgaac gcgtactctt tagcgcgctt ggcgtctctg
    30181 accgcgagat gaactggaag cagtatctct cagccattct tggcctgaat atactggggc
    30241 tggcggtgct gttttttatg ttgctcggtc agcactatct gccgcttaat ccacagcagt
    30301 tgccagggct gtcgtgggat ctggcgctca ataccgccgt cagctttgtc accaatacca
    30361 actggcaatc ttatagcggt gaaaccacgt tgagctattt cagccagatg gcgggcttaa
    30421 cggtacaaaa ctttctttct gccgccagcg ggattgcggt gatttttgcc ctcattcgtg
    30481 catttacccg ccagagcatg agcacactcg ggaatgcctg ggtcgatctg ctacgcatca
    30541 cgttatgggt gctagtccct gtggcgttgt tgatcgcact gttttttatt caacaaggtg
    30601 cgctgcaaaa ctttctgccc tatcaggcgg tgaataccgt tgaaggagca caacagctgt
    30661 tacccatggg gccagtagct tctcaggaag cgatcaaaat gctcggaact aacggcggtg
    30721 gcttttttaa tgccaactcg tcgcatccgt ttgaaaaccc aaccgcactg accaacttcg
    30781 tgcaaatgct ggcgattttc ttgatcccaa cagcgctgtg ctttgccttt ggtgaagtgg
    30841 cgggcgatcg tcgccagggg cgcatgttgc tgtgggcgat gtcggtgatt tttgtcatct
    30901 gcgtaggcgt agtgatgtgg gcagaagttc agggtaatcc tcatctgctg gcgctcggcg
    30961 cggacagcag catcaatatg gaaggtaaag agagccgttt cggcgtgctg gtcagtagcc
    31021 tgtttgcggt cgtgactacg gcggcttcct gcggcgcggt gattgcgatg catgattcgt
    31081 ttaccgctct tggtggcatg gtgccgatgt ggttgatgca aattggtgaa gtggtattcg
    31141 gcggcgtcgg ttccggcctt tacggcatga tgctgtttgt cctgctggcg gtgtttattg
    31201 ccgggctgat gattggtcgt acaccggaat atctgggtaa aaaaatcgac gtacgcgaga
    31261 tgaaactgac tgcactggcg attctggtca ccccgacgct ggtgctgatg ggcgcggcgc
    31321 tggcaatgat gaccgacgcc ggacgtagcg ccatgctcaa ccctggcccg catggtttta
    31381 gcgaagtgct gtacgccgtg tcatccgccg ctaacaacaa cggcagcgcc tttgccggat
    31441 taagcgccaa ctctccattc tggaactgtt tactggcgtt gtgcatgttt gtcgggcgct
    31501 tcggggtgat tatcccggtg atggcaattg ccggttcgct ggtgagtaaa aagagccaac
    31561 ccgccagctc cggcacattg ccaacgcacg gcccgctgtt tgttggcctg ttaatcggca
    31621 ccgtgttgct ggttggcgca ctgaccttta tccctgccct ggcgcttggt ccggtggcgg
    31681 aatatctctc ctgatgatat tgagtgagca ctgaatatga gtcgtaaaca actggcgcta
    31741 ttcgaaccaa cacttgtcgt tcaggcgctg aaagaagcgg tgaaaaaatt aaacccgcag
    31801 gcgcaatggc gcaatccggt gatgtttatc gtctggatcg gcagtctgct gaccacctgt
    31861 attagcatcg cgatggcaag cggtgtgatg cctggtaatg cgctgtttag cgcggcaatt
    31921 agcggctggc tgtgggtcac cgtactgttc gctaatttcg ccgaggcgtt ggcagaaggc
    31981 cgcagtaaag cgcaggccaa cagtctgaaa ggggtgaaaa aaaccgcttt tgctcgcaag
    32041 ctgcgcgaac cgaaatatgg cgctgtggca gacaaagttc ctgccgatca actgcgtaaa
    32101 ggcgatatcg tactggtaga agctggcgat attatcccct gcgatggtga agtcattgaa
    32161 ggcggcgcat cggtcgatga aagcgccatc accggggaat cggctccggt gatccgtgaa
    32221 tccggcggtg attttgcctc cgtcactggc ggcacgcgta ttctttctga ctggctggtg
    32281 attgagtgca gcgttaaccc cggcgagaca tttctggatc ggatgatcgc gatggtggaa
    32341 ggtgcgcagc gacgtaaaac gccgaacgag attgccctga ccattctcct gattgccctg
    32401 actatcgtct ttttactggc aaccgccacg ctgtggccgt tttccgcgtg gggcggtaat
    32461 gcagtcagcg taacggtact ggtggcactg ctggtctgtc tgatcccaac cactattggc
    32521 ggcctgttgt cagcgattgg cgtcgccggg atgagtcgga tgctgggcgc gaatgttatt
    32581 gccaccagcg ggcgtgcagt tgaagcggcg ggcgacgtgg acgtcctgct gctggataaa
    32641 accggcacca tcacactcgg taaccgtcag gcgtcggagt ttatccctgc gcagggcgtg
    32701 gatgaaaaaa cgctggctga cgccgcacaa ctggcttcgc tggctgatga aacgccggaa
    32761 ggccgcagta ttgtgatcct cgccaagcag cgttttaacc tgcgcgagcg cgatgtgcag
    32821 tcgctccatg ccacctttgt accgtttact gcgcaaagcc ggatgagcgg gatcaacatc
    32881 gacaaccgca tgatccgtaa aggttctgtc gatgccattc gccgccatgt tgaggctaac
    32941 ggcggtcact tccctgccga tgttgatcaa aaagtcgatc aagttgcgcg tcagggagcc
    33001 acgccgctgg tggtggtgga aggttctcgt gtgctgggcg ttattgcgct gaaagatatc
    33061 gtcaaaggcg gtattaaaga gcgcttcgcc cagctgcgta aaatgggcat taaaacggtg
    33121 atgattaccg gcgataaccg tctgactgcc gccgcgattg ccgcggaagc gggcgtcgat
    33181 gattttctcg ccgaagcaac accggaggcc aagctggcgt tgattcgtca gtatcaggca
    33241 gaaggccgtt tagtggcgat gaccggcgat ggcaccaacg atgctccggc gctggcgcag
    33301 gcggatgtcg cggtggcgat gaactccggc acccaggcgg cgaaagaagc aggcaatatg
    33361 gtggatctcg actccaaccc gaccaagttg atcgaggtgg tgcacattgg caaacagatg
    33421 ctgatgaccc gtggctcgtt gaccaccttc agcattgcca acgatgtggc gaaatacttc
    33481 gccattattc cagcggcgtt cgcggcaacg tatccgcagt taaatgcgct gaacatcatg
    33541 cgcctgcatt cgcccgactc cgccattctc agtgcggtca ttttcaacgc cttgattatc
    33601 gtctttttga ttcccctggc gttaaaaggc gtgagttata aaccgcttac cgcttctgcc
    33661 atgttgcgcc gtaacttatg gatttacggt ctgggtgggc tgctggtgcc gtttattggt
    33721 atcaaagtca ttgatttact gctaaccgtt tgcggtctgg tgtgaggttt accatgagtg
    33781 gattacgtcc ggcattatcg acatttctct ttctgttatt gattactggc ggcgtttacc
    33841 cgctgctgac caccgcactg gggcaatggt ggtttccctg gcaggccaac ggttcattga
    33901 ttcgtgaagg tgatacggtg cgcggttcgg cattaatcgg gcaaaatttt accggcaacg
    33961 gctattttca tggtcgcccg tcggcaacag cagaaatgcc ctataatcca caggcttctg
    34021 gcgggagcaa tctggcagtc agtaacccgg tgctggataa acagatagcc gcacgcgttg
    34081 ccgcattacg ggccgctaac ccggacgcca gcacgagcgt tccggttgaa ctggtgacag
    34141 cgtcagcaag cgggctggac aataatatta ccccgcaagc ggcggcctgg cagatcccac
    34201 gcgtggcgaa agcgcgtaat ctcagcgttg aacagctcac gcaactgatc gcaaaataca
    34261 gccaacaacc gctggtgaac tatatcggcc agccggtcgt caacgttgta gaactcaatc
    34321 tggcgctgga taagcttgat gaataacgaa cccttacgtc ccgaccccga tcgtctgctg
    34381 gaacaaactg ccgcgccgca tcgggggaag ctgaaagttt tcttcggtgc ctgcgcaggc
    34441 gtcggaaaga cctgggcgat gctggcagaa gcccagcgac tgcgggcgca agggctggat
    34501 attgtggttg gcgtggtaga aacccacggg cggaaagata ccgccgcaat gctggaaggt
    34561 ctggctgttc tgccgctgaa acgccaggcg taccgtgggc ggcatatcag cgagtttgat
    34621 ctcgatgccg ccctcgcccg ccgtccggca ctgatcttaa tggacgaact ggcgcacagt
    34681 aatgcgccag gttctcgtca tcctaaacgc tggcaggaca tcgaagagct gctggaagca
    34741 ggcattgatg ttttcactac cgtcaacgtt cagcatctgg aaagcctgaa cgatgtggtc
    34801 agtggcgtaa ccggaattca ggttcgggaa accgtgcccg atcctttttt cgatgccgcc
    34861 gacgacgtag tactggtgga cttgcccccg gacgatctgc gccaacgact gaaagaaggc
    34921 aaagtctata ttgccgggca ggcagaacgc gccattgagc attttttccg caaaggcaat
    34981 ctgatcgccc tgcgcgagct ggcgctacgc cgtactgccg atcgcgtaga tgagcaaatg
    35041 cgcgcgtggc gggggcatcc tggcgaagag aaagtctggc acacgcgcga cgcgatcctt
    35101 ttatgcatcg ggcataacac cggcagtgag aaactggtcc gcgcggcggc gcggctggcg
    35161 tcgcgcctgg gcagtgtctg gcacgcggtg tatgttgaaa cccctgccct gcatcgctta
    35221 ccggagaaaa aacgtcgggc aattctcagc gccttacgtc tggcgcagga gttgggcgcg
    35281 gagacggcaa cactttctga tccagcggaa gaaaaagcag tagtgcgtta tgcccgtgaa
    35341 cataatctcg gcaagattat tctcggtcgc ccggcctcgc gccgctggtg gcgtcgggaa
    35401 acgtttgctg accggctggc gcgcatcgcc cccgatctcg atcaggtact ggtcgcgctt
    35461 gatgaaccac ccgcccgcac gattaataac gcgccggata gccgctcttt taaagacaag
    35521 tggcgggtac agattcaggg atgcgtggtt gccgccgcgt tatgcgccgt tatcacctta
    35581 attgccatgc agtggctgat ggcgtttgat gccgccaacc tggtgatgct gtatctgctt
    35641 ggcgtggttg tggtggcact attttacgga cgctggcctt cggtggttgc gaccgtcatt
    35701 aatgtggtga gtttcgatct cttttttatc gccccacgcg gcacgctcgc cgtctctgat
    35761 gtgcaatatc tgctgacctt cgcggtgatg ttaaccgtcg ggctggtgat cgggaacctt
    35821 actgctggcg tgcgttatca ggcgcgggta gcccgttacc gcgaacaacg cacacggcac
    35881 ttatatgaaa tgtccaaagc tctggctgtg ggccgtagtt cgcaggatat cgccgccacc
    35941 agcgaacagt ttattgcctc cacgtttcat gcccgtagcc aggtgttgct gcctgatgac
    36001 aacggtaaat tgcagccttt aacacatccg caaggaatga cgccgtggga cgatgccatc
    36061 gcgcagtgga gttttgataa aggcctgcct gcgggcgcgg gcaccgacac gttacccggt
    36121 gtaccgtacc agattttgcc gctaaaaagc ggcgagaaaa cctacggact ggtggtggtg
    36181 gaaccgggga atctgcgcca gttgatgatc ccggaacagc agcgcctgct ggagacgttt
    36241 acgctgttag tcgccaatgc ccttgagcga ctgacactga ccgccagcga agaacaggcg
    36301 cggatggcaa gcgaacgtga acagatccgc aacgccctgc tggcggcgct ttcgcatgat
    36361 ttacgcacgc cgcttacggt gctgttcggt caggcagaaa tcttaacgct cgatctggca
    36421 agcgaaggat cgccccacgc ccgccaggcc agcgagattc gtcagcatgt gctgaacacc
    36481 acccgactgg tgaataatct actggatatg gcgcgaattc agtccggcgg ctttaatttg
    36541 aagaaagagt ggttaacgct ggaagaagtg gtcggcagcg cgctgcaaat gctggaaccg
    36601 ggtttatcgt cgcccatcaa tctttctctg ccagagccgc tgaccttaat ccacgttgac
    36661 gggccactct ttgaacgggt gctgattaac ctgctggaga acgcggtgaa atatgcgggg
    36721 gcgcaggccg aaattggtat caatgcccac atcgagggcg aaaatctaca actggatgtc
    36781 tgggataacg gccccggtct tccaccaggc caggagcaga cgatatttga taagtttgct
    36841 cgcgggaata aagagtcggc ggtaccgggt gtagggcttg ggttggcaat ttgtcgggcg
    36901 atagtggatg tacacggcgg caccattacc gcattcaacc gaccggaagg tggtgcctgt
    36961 tttcgtgtta cacttcccca gcaaacagcc cctgaacttg aagaatttca tgaggatatg
    37021 tgacaaacgt tctgattgtt gaagatgaac aggctattcg tcgctttctg cgcacggcgc
    37081 tggagggcga tgggatgcgc gtctttgagg ccgaaacgct gcaacgcggc ttgctggaag
    37141 cggctacccg taagccagat ttgattattc tcgatctcgg cctgcccgat ggtgatggga
    37201 ttgagtttat ccgcgacctg cgccagtgga gcgcggtgcc ggtgattgtg ctttccgcac
    37261 gtagcgaaga gagcgacaaa atcgccgcgc tggatgccgg agcggatgat tatctgagta
    37321 agccgtttgg cattggcgaa ttgcaggccc gtctgcgcgt cgctttacgt cgccactccg
    37381 ccaccgccgc gcccgatccg ctggtgaaat tttccgatgt taccgtcgat ttagccgccc
    37441 gcgttatcca tcggggcgag gaagaggtgc atctcacccc gattgagttc cgcctgctgg
    37501 cagtgttgct caacaacgcc ggaaaagtgc tcacccagcg ccagttactc aatcaggtgt
    37561 ggggaccaaa cgcggtcgaa cacagccact atttgcgtat ttatatgggg catctgcgac
    37621 aaaaactgga gcaagatccc gcccgccccc gccattttat tactgaaacc ggtatt
//
LOCUS       DAFGPF010000041        37495 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFGPF010000041 DAFGPF010000000
VERSION     DAFGPF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37495
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.041"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            101..1045
                     /gene="leuO"
                     /locus_tag="LSX49_002268"
     CDS             101..1045
                     /gene="leuO"
                     /locus_tag="LSX49_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HBL7168670.1"
                     /translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     ALGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQTWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
     gene            complement(1206..1244)
                     /locus_tag="LSX49_002269"
     CDS             complement(1206..1244)
                     /locus_tag="LSX49_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168671.1"
                     /translation="MKRNDKILHYRG"
     gene            1363..3087
                     /gene="ilvI"
                     /locus_tag="LSX49_002270"
     CDS             1363..3087
                     /gene="ilvI"
                     /locus_tag="LSX49_002270"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HBL7168672.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTSGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHLQLKEAVEALNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGARFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTNGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPQELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            3090..3581
                     /gene="ilvN"
                     /locus_tag="LSX49_002271"
     CDS             3090..3581
                     /gene="ilvN"
                     /locus_tag="LSX49_002271"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HBL7168673.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            3593..3679
                     /locus_tag="LSX49_002272"
     CDS             3593..3679
                     /locus_tag="LSX49_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HBL7168674.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            3761..4765
                     /gene="cra"
                     /locus_tag="LSX49_002273"
     CDS             3761..4765
                     /gene="cra"
                     /locus_tag="LSX49_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HBL7168675.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            5367..5825
                     /gene="mraZ"
                     /locus_tag="LSX49_002274"
     CDS             5367..5825
                     /gene="mraZ"
                     /locus_tag="LSX49_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBL7168676.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            5827..6768
                     /gene="rsmH"
                     /locus_tag="LSX49_002275"
     CDS             5827..6768
                     /gene="rsmH"
                     /locus_tag="LSX49_002275"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBL7168677.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            6765..7130
                     /gene="ftsL"
                     /locus_tag="LSX49_002276"
     CDS             6765..7130
                     /gene="ftsL"
                     /locus_tag="LSX49_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBL7168678.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            7146..8912
                     /gene="ftsI"
                     /locus_tag="LSX49_002277"
     CDS             7146..8912
                     /gene="ftsI"
                     /locus_tag="LSX49_002277"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HBL7168679.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLTLSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTVPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     gene            8899..10386
                     /gene="murE"
                     /locus_tag="LSX49_002278"
     CDS             8899..10386
                     /gene="murE"
                     /locus_tag="LSX49_002278"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBL7168680.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSAHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TDVNYHDSGATICFSSSWGDGEIESRLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVVVVTDDNPRTEEPRAIINDILAGMLDAGYAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            10383..11741
                     /gene="murF"
                     /locus_tag="LSX49_002279"
     CDS             10383..11741
                     /gene="murF"
                     /locus_tag="LSX49_002279"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBL7168681.1"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLVNLKAVPGRLFPIKLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDCVLSVGK
                     QSHAISTASGVGEHFSDKTALIARLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     gene            11735..12817
                     /gene="mraY"
                     /locus_tag="LSX49_002280"
     CDS             11735..12817
                     /gene="mraY"
                     /locus_tag="LSX49_002280"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBL7168682.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            12820..14136
                     /gene="murD"
                     /locus_tag="LSX49_002281"
     CDS             12820..14136
                     /gene="murD"
                     /locus_tag="LSX49_002281"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBL7168683.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGGLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWVNDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            14136..15380
                     /gene="ftsW"
                     /locus_tag="LSX49_002282"
     CDS             14136..15380
                     /gene="ftsW"
                     /locus_tag="LSX49_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HBL7168684.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            15377..16444
                     /gene="murG"
                     /locus_tag="LSX49_002283"
     CDS             15377..16444
                     /gene="murG"
                     /locus_tag="LSX49_002283"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBL7168685.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEVGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRAARA"
     gene            16498..17973
                     /gene="murC"
                     /locus_tag="LSX49_002284"
     CDS             16498..17973
                     /gene="murC"
                     /locus_tag="LSX49_002284"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBL7168686.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            17966..18886
                     /gene="ddlB"
                     /locus_tag="LSX49_002285"
     CDS             17966..18886
                     /gene="ddlB"
                     /locus_tag="LSX49_002285"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL7168687.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQSAGLPVAPWVALTRAEFEKGLNDKQLAEISSLGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPAGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            18888..19718
                     /gene="ftsQ"
                     /locus_tag="LSX49_002286"
     CDS             18888..19718
                     /gene="ftsQ"
                     /locus_tag="LSX49_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HBL7168688.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            19715..20977
                     /gene="ftsA"
                     /locus_tag="LSX49_002287"
     CDS             19715..20977
                     /gene="ftsA"
                     /locus_tag="LSX49_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBL7168689.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            21038..22189
                     /gene="ftsZ"
                     /locus_tag="LSX49_002288"
     CDS             21038..22189
                     /gene="ftsZ"
                     /locus_tag="LSX49_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBL7168690.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            22290..23207
                     /gene="lpxC"
                     /locus_tag="LSX49_002289"
     CDS             22290..23207
                     /gene="lpxC"
                     /locus_tag="LSX49_002289"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HBL7168691.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            23437..23949
                     /gene="secM"
                     /locus_tag="LSX49_002290"
     CDS             23437..23949
                     /gene="secM"
                     /locus_tag="LSX49_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308128.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HBL7168692.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLETNTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLS"
     gene            24011..26716
                     /gene="secA"
                     /locus_tag="LSX49_002291"
     CDS             24011..26716
                     /gene="secA"
                     /locus_tag="LSX49_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBL7168693.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEIEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            26776..27174
                     /gene="mutT"
                     /locus_tag="LSX49_002292"
     CDS             26776..27174
                     /gene="mutT"
                     /locus_tag="LSX49_002292"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HBL7168694.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFSGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRVYVE"
     gene            complement(27262..27459)
                     /gene="yacG"
                     /locus_tag="LSX49_002293"
     CDS             complement(27262..27459)
                     /gene="yacG"
                     /locus_tag="LSX49_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HBL7168695.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(27469..28212)
                     /gene="zapD"
                     /locus_tag="LSX49_002294"
     CDS             complement(27469..28212)
                     /gene="zapD"
                     /locus_tag="LSX49_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HBL7168696.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDSENGQVPERLDFELACC"
     gene            complement(28212..28832)
                     /gene="coaE"
                     /locus_tag="LSX49_002295"
     CDS             complement(28212..28832)
                     /gene="coaE"
                     /locus_tag="LSX49_002295"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL7168697.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            28857..28901
                     /locus_tag="LSX49_002296"
     CDS             28857..28901
                     /locus_tag="LSX49_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168698.1"
                     /translation="MIIKTLKMSARKRN"
     gene            29057..30100
                     /gene="guaC"
                     /locus_tag="LSX49_002297"
     CDS             29057..30100
                     /gene="guaC"
                     /locus_tag="LSX49_002297"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBL7168699.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQRW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     gene            complement(30135..31337)
                     /gene="hofC"
                     /locus_tag="LSX49_002298"
     CDS             complement(30135..31337)
                     /gene="hofC"
                     /locus_tag="LSX49_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HBL7168700.1"
                     /translation="MASKQLWRWRGITGDGNAQDGMLWAESRALLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGVAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGW
                     LLVLFGFLLAIANKLLMRHPTRLIARQKLLLRIPIMGSLMRGQKLTQIFTILTLTQSA
                     GISFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNAGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(31327..32712)
                     /gene="gspE"
                     /locus_tag="LSX49_002299"
                     /pseudo
     CDS             complement(31327..32712)
                     /gene="gspE"
                     /locus_tag="LSX49_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414649.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
     gene            complement(32722..33162)
                     /gene="ppdD"
                     /locus_tag="LSX49_002300"
     CDS             complement(32722..33162)
                     /gene="ppdD"
                     /locus_tag="LSX49_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HBL7168701.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLNTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     gene            complement(33366..34259)
                     /gene="nadC"
                     /locus_tag="LSX49_002301"
     CDS             complement(33366..34259)
                     /gene="nadC"
                     /locus_tag="LSX49_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBL7168702.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     PLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     gene            34347..34898
                     /gene="ampD"
                     /locus_tag="LSX49_002302"
     CDS             34347..34898
                     /gene="ampD"
                     /locus_tag="LSX49_002302"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HBL7168703.1"
                     /translation="MLLEQGWLAGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDRYPDIANNMTGHCDIAPD
                     RKTDPGPAFDWARFRALVSKETT"
     gene            34895..35749
                     /gene="ampE"
                     /locus_tag="LSX49_002303"
     CDS             34895..35749
                     /gene="ampE"
                     /locus_tag="LSX49_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HBL7168704.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     CMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHAHATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHALDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(35792..37162)
                     /gene="aroP"
                     /locus_tag="LSX49_002304"
     CDS             complement(35792..37162)
                     /gene="aroP"
                     /locus_tag="LSX49_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HBL7168705.1"
                     /translation="MEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAG
                     PGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLY
                     VLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKV
                     IAVVAMIIFGAWLLFSGNGGPQASVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLEL
                     VGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFH
                     ELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVN
                     TILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGV
                     VTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTA
                     KAVKAH"
BASE COUNT         8861 a         9112 c        10431 g         9091 t
ORIGIN      
        1 ctttttctta ttttatatgc atgataaatc atattctcga ggattatttc tctgcattcc
       61 aataagggaa agggagttaa gtgtgacagt ggagttaagt atgccagagg tacaaacaga
      121 tcatccagag acggcggagt taagcaagcc acagctacgc atggtcgatc tcaacttatt
      181 aaccgttttc gatgccgtga tgcaggagca aaacatcacc cgtgccgctc atgctctggg
      241 aatgtcgcaa cctgcggtca gtaacgctgt tgcacgcctg aaggtgatgt ttaatgacga
      301 gctttttgtt cgttatggtc gtggtattca accgactgct cgcgcatttc aactttttgg
      361 ctcagttcgt caggcattgc aattagtaca aaatgaatta ccaggttcag gctttgagcc
      421 tgccagtagt gaacgtgtat ttcatctttg tgtctgcagc ccgttagaca gcattctgac
      481 ctcgcagatt tataatcaca ttgagcagat tgcgccaaat atacatgtta tgttcaagtc
      541 ttcattaaat cagaacactg aacatcagct gcgttatcag gaaacggagt ttgtgattag
      601 ttatgaagac ttccatcgtc ctgaatttac cagcgtgcca ttatttaaag atgaaatggt
      661 gttggtagcc agcaaaaatc atccaacaat taaaggcccg ttactgaaac atgatgttta
      721 taacgaacaa catgcggcgg tttcgctcga tcgtttcgcg tcatttagtc aaacctggta
      781 tgacacggta gataagcaag ccagtatcgc gtatcagggc atggcaatga tgagcgtact
      841 tagcgtggtg tcgcaaacgc atctggttgc tattgcgccg cgttggttgg ctgaagagtt
      901 cgctgaatcc ttagagttac aggtattacc gctgccgtta aaacaaaaca gcagaacctg
      961 ttatctctcc tggcatgaag ctgccgggcg cgataaaggc catcagtgga tggaagagca
     1021 attagtctca atttgcaaac gctaactgaa tgcagaatag gtcagacatc aatgtctggt
     1081 ttattctgca ttttttattg aatgtagaat tttattctga atatttgtgc tctctatttt
     1141 aggattaatt aaaaaaatag agaaattgct gtaagttgta ggattcagcc gatttattat
     1201 caatttcatc ctctgtaatg gaggatttta tcgtttcttt tcacctttcc tcctgtttat
     1261 tcttattacc ccgtgtttat gtctctgtct gccaattgct taagcaagat cggacggtta
     1321 atgtgtttta cacatttttt ccgtcaaaca gtgaggcagg ccatggagat gttgtctgga
     1381 gccgagatgg tcgtccgatc gcttatcgat cagggcgtta aacaagtatt cggttatcct
     1441 ggaggcgcgg tccttgatat ttacgatgca ttgcataccg tgggtggtat cgatcatgtt
     1501 ttagttcgcc atgagcaggc ggcggtgcat atggccgatg gtctggcgcg cgcgaccggg
     1561 gaagtcggcg tcgtgctggt aacgtcgggt ccaggggcga ccaatgcgat tactggcatt
     1621 gccaccgctt atatggattc cattccatta gttgtccttt ccgggcaggt agcgacttcg
     1681 ttgataggtt atgatgcctt tcaggagtgc gacatggtgg ggatttctcg cccggtggtt
     1741 aaacacagtt ttctggttaa gcaaacggaa gacattccgc aggtgctgaa aaaggctttc
     1801 tggctagcgg caagtggtcg tcctggaccc gtggtcgttg atttaccgaa agatattcta
     1861 aatccggcga acaaattacc ctatgtctgg ccggagtcgg tcagtatgcg ttcttacaat
     1921 cccacgacct ccgggcataa agggcaaatt aagcgcgctc tgcaaacgct ggtggcggca
     1981 aaaaaaccgg ttgtctacgt aggcggtggg gcaatcacgg cgggctgcca tctgcagttg
     2041 aaagaagcgg tggaggcgtt gaatctgccc gttgtttcct ctttgatggg gctgggggcg
     2101 tttccggcaa cgcatcgtca ggcactgggc atgttgggaa tgcacggtac ctacgaagcc
     2161 aatatgacga tgcataacgc ggatgtgatt ttcgccgtcg gggcacgttt tgatgaccga
     2221 acgacgaaca atctggcaaa atactgccca aatgccactg ttctgcatat cgatattgat
     2281 ccaacctcaa tttctaaaac cgtgactgct gatatcccga ttgtggggga tgctcgccag
     2341 gtcctagaac aaatgcttga actcctgtcg caagaatccg cccatcaacc gctggatgag
     2401 atccgcgact ggtggcagca gattgaacag tggcgcgctc gtcagtgcct gaaatatgac
     2461 actcacagtg aaaagattaa accgcaggcg gtgatcgaga ctctttggcg gttgactaat
     2521 ggggacgctt acgtgacgtc cgatgtcggg cagcaccaga tgtttgctgc gctttattat
     2581 ccattcgaca aaccgcgtcg ctggatcaac tctggcggcc tcggcacgat gggttttggt
     2641 ttacctgcgg cactgggcgt caaaatggcg ttgccagaag aaaccgtggt ttgcgtcact
     2701 ggtgacggca gtattcagat gaacatccag gaactgtcta ccgccttgca atacgagttg
     2761 cccgtactgg tggtgaatct caataatcgc tatctgggga tggtgaagca gtggcaggac
     2821 atgatctatt ccggccgtca ttcacaatct tatatgcagt ccttaccaga cttcgtccgt
     2881 ctggcggaag cctatggtca cgtcgggatc cagatctctc atccgcaaga actggaaagc
     2941 aaacttagcg aggcgctgga acaggtgcgc aataatcgcc tggtgtttgt tgatgttacc
     3001 gtcgatggca gtgagcacgt ctacccgatg cagattcgcg ggggcggaat ggatgaaatg
     3061 tggttaagca aaacggagag aacctgatta tgcgccggat attatcagtc ttactcgaaa
     3121 atgaatcagg cgcgttatcc cgcgtgattg gccttttttc ccagcgtggc tacaacattg
     3181 aaagcctgac cgttgcgcca accgacgatc cgacattatc gcgtatgacc atccagaccg
     3241 tgggcgatga aaaagtgctt gagcaaatcg aaaagcaatt acacaagctg gtcgatgtct
     3301 tgcgcgtgag cgagttgggg cagggcgcgc acgttgagcg ggaaatcatg ctggtgaaaa
     3361 ttcaggccag cggttacggg cgtgacgaag tgaaacgtaa tacggaaata ttccgtgggc
     3421 aaattatcga tgtcacaccc tcgctttata ccgttcaatt agcaggcacc agcgataagc
     3481 ttgatgcatt tttagcatcg attcgcgatg tggcgaaaat tgtggaagtt gctcgctctg
     3541 gtgtggtcgg actttcgcgc ggcgataaaa taatgcgttg agaatgatct caatgcgcaa
     3601 tttgcagccc aacatgtcac gttgggcttt ttttgcgaaa tcagtgggaa cctggaataa
     3661 aagcagttgc cgcagttaat tttctgcgct tagatgttaa tgaatttaac ccataccagt
     3721 acaatggcta tggtttttac attttacgca aggggcaatt gtgaaactgg atgaaatcgc
     3781 tcggctggcg ggagtgtcgc ggaccactgc aagctatgtt attaacggca aagcgaagca
     3841 ataccgtgtg agcgacaaaa ccgttgaaaa agtcatggct gtggtgcgtg agcacaatta
     3901 ccacccgaac gccgtggcag ctgggcttcg tgctggacgc acacgttcta ttggtcttgt
     3961 gatccccgat ctggagaaca ccagctatac ccgcatcgct aactatcttg aacgccaggc
     4021 gcggcaacgg ggttatcaac tgctgattgc ctgctcggaa gatcagcccg acaacgaaat
     4081 gcgctgtatt gagcaccttt tacagcgtca ggttgatgcc attattgttt cgacgtcgtt
     4141 gccacctgag catccttttt atcaacgctg ggctaacgac ccgttcccga ttgtcgcgct
     4201 ggaccgcgcc ctcgatcgtg aacacttcac cagcgtggtt ggtgccgatc aggatgatgc
     4261 cgaaatgctg gcggaagagt tacgtaagtt tcccgccgag acggtgcttt atcttggcgc
     4321 gctgccggag ctttctgtca gcttcctgcg tgaacaaggc ttccgtactg cctggaaaga
     4381 tgatccgcgc gaagtgcatt tcctttatgc caacagctat gagcgggagg cagctgccca
     4441 gttattcgaa aaatggctgg aaacgcatcc gatgccgcag gcgctgttca caacgtcgtt
     4501 tgcgttgttg caaggggtga tggatgtcac gctacgtcgc gacggcaaac tgccttctga
     4561 cctggcaatt gccacctttg gcgataacga actgctcgac ttcttacagt gcccggtgct
     4621 ggcagtggct caacgtcacc gcgatgtcgc agaacgtgtg ctggagattg tcctggcgag
     4681 cctggacgaa ccgcgtaagc caaaacctgg tttaacgcgc attaaacgta atctctatcg
     4741 ccgcggcgtg ctcagccgta gctaaaccgc gaacaaaagt acgcgccagg tgaatttctc
     4801 tctggcgcgt tgagtacggg aatggacatc aatatcctta aagtaaataa gactattcct
     4861 ggctattatt gataaatgct tttaaacccg cccgttaatt aactcacctg ctgaaatgca
     4921 caataattaa atgatattga cagcgcgttt ttgcattatt ttgttacatg cagagatgaa
     4981 ttgccgattt aacaaacact tttctttgtt tttgcgcaaa cctgctggca tcaagcgcca
     5041 cacagacgca acagggactg ttaaccagag aagatatgtc ctaaaatgcc gctcgcgtcg
     5101 caaactgaca ctttatattt gctgtggaaa atagtgagtc attttaaaac ggtgatgacg
     5161 atgagggatt ttttcttaca gctattcata acgttaattt gcttcgcacg ttggacgtaa
     5221 aataaacaac gctgatatta gccgtaaaca tcgggttttt tacctcggta tgccttgtga
     5281 ctggcttgac aagcttttcc tccgctccgt aaactccttt tagtgggaaa ttgtggggca
     5341 aagtgggaat aaggggtgag gctggcatgt tccggggagc aacgttagtc aatctcgaca
     5401 gcaaagggcg cttatcagtg cctacccgtt atcgggaaca gctgcttgag aacgctgccg
     5461 gtcaaatggt ttgcaccatt gacattcatc acccgtgcct gctgctttac cccctgcctg
     5521 aatgggaaat tatcgagcaa aaattatcgc gtctgtcgag catgaacccg gttgagcgcc
     5581 gtgtgcagcg cctactgtta ggtcatgcca gcgaatgtca gatggatggc gcaggtcgat
     5641 tgttaatcgc gccagtactg cggcaacatg ccgggctgac aaaagaagtg atgctggttg
     5701 gacagttcaa caagtttgag ctgtgggatg aaacaacctg gcatcaacag gtcaaggaag
     5761 atatcgacgc agagcagttg gctaccggag acttatcgga gcgactgcag gacttgtctc
     5821 tataaaatga tggaaaacta taaacatact acggtgctgc tggatgaagc cgttaatggc
     5881 ctcaatatcc gtcctgatgg catctacatt gatgggactt ttggtcgcgg tggtcactca
     5941 cgtctgatcc tctcgcagct tggcgaagag gggcgtttgc tggcgatcga tcgcgacccg
     6001 caggctatcg ccgttgcgaa gactattgat gatccgcgct tctccatcat ccacggacct
     6061 ttctctgcgc tgggcgaata tgttgccgag cgcgatctta tcggcaagat cgacggcatt
     6121 ctcctcgatc ttggcgtctc ttcaccgcaa cttgatgatg ctgaacgcgg cttttccttt
     6181 atgcgcgatg gtccgctgga catgcgtatg gacccaaccc gtgggcagtc agccgctgaa
     6241 tggctacaaa ccgcagaaga agccgatatc gcctgggtat tgaaaaccta tggtgaagag
     6301 cgttttgcca aacgcattgc tcgcgccatt gtcgagcgta accgcgaaca gccgatgacc
     6361 cgcaccaaag aactggcgga agtcgtggct gccgcaacgc cggtgaaaga taagtttaaa
     6421 catcccgcga cccgtacctt ccaggcggtg cgcatttggg taaacagtga actggaggag
     6481 atagagcagg cgctaaaaag ctcgctcaat gtgctggccc cgggggggcg gctttcgatc
     6541 atcagcttcc actcacttga agaccgcatt gtgaaacgtt ttatgcgtga aaacagccgc
     6601 ggtccgcaag ttccggcagg gttaccgatg acagaagagc agctcaaaaa actggggggg
     6661 cgtcagttgc gagcactagg taagttgatg ccgggcgaag aagaggtggc tgagaaccct
     6721 cgtgcccgta gttcagttct gcgtattgca gagaggacga acgcatgatc agcagagtga
     6781 cagaagctct aagcaaagtt aaaggatcga tgggaagcca cgagcgccat gccttgcctg
     6841 gcgttatcgg tgacgatctt ttgcgatttg ggaagctgcc actctgcctg ttcatttgca
     6901 ttattttgac ggcggtgacc gtggtaacca cggcgcacca tacccgttta ctgaccgctc
     6961 agcgcgaaca actggtgctg gagcgagatg ctttagacat tgaatggcgc aacctgatcc
     7021 ttgaagagaa tgcgctcggc gaccatagcc gggtggaaag gatagccacg gaaaagctgc
     7081 aaatgcagca tgttgatccg tcacaagaaa atatcgtagt gcaaaaataa ggataaacgc
     7141 gacgcatgaa agcagcggcg aaaacgcaga aaccaaaacg tcaggaagaa catgccaact
     7201 ttatcagttg gcgttttgcg ttgttatgcg gctgtattct cctggcgctg gcttttctgc
     7261 tcggacgcgt agcgtggtta caagttatct ccccggatat gctggtgaaa gagggcgaca
     7321 tgcgttctct tcgcgttcag caagtttcca cctcccgcgg catgattact gaccgttctg
     7381 gtcgcccgtt agcggtgagt gtgccagtaa aagcgatttg ggctgacccg aaagaagtgc
     7441 atgacgctgg cggtatcagc gtcggtgacc gctggaaggc gctggctaac gcgctcaata
     7501 ttccgctgga tcagctctca gcccgcatta acgccaaccc gaaagggcgc tttatttatc
     7561 tggcgcgtca ggtaaaccct gacatggcgg actacatcaa aaaactgaaa ctgccgggaa
     7621 ttcatctgcg tgaagaatct cgccgttatt atccatccgg cgaagtgact gctcacctca
     7681 tcggctttac taacgtcgat agccaaggga ttgagggggt cgagaagagt ttcgataaat
     7741 ggcttaccgg gcagccgggt gagcgcattg tgcgtaaaga ccgctatggt cgcgtaattg
     7801 aagatatttc ttctactgac agccaggcag cgcacaacct gacgctgagt attgatgaac
     7861 gcctgcaggc gctggtttat cgcgaactga acaacgcagt ggcctttaac aaggctgaat
     7921 ctggtagcgc cgtgctggtg gatgtcaaca ccggtgaagt gctggcgatg gctaacagcc
     7981 cgtcatacaa cccaaataat ctgagcggca cgccgaaaga agcgatgcgt aaccgtacca
     8041 tcaccgacgt gtttgaaccg ggctcaacgg ttaaaccgat ggtggtgatg accgcgttgc
     8101 aacgtggcgt ggtgcgggaa aactcggtac tcaataccgt tccttatcga attaacggcc
     8161 acgaaatcaa agacgtggca cgctacagcg aattaaccct gaccggggta ttacagaagt
     8221 cgagtaacgt cggtgtttcc aaactggcgt tagcgatgcc gtcctcagcg ttagtagata
     8281 cttactcacg ttttgggctg ggaaaagcga ccaatttggg gttggtcgga gaacgcagtg
     8341 gcttatatcc tcaaaaacaa cggtggtctg acatagagag ggccaccttc tctttcggct
     8401 acgggctaat ggtaacaccg ttacagttag cgcgagtcta cgcaactatc ggcagctacg
     8461 gcatttatcg cccactgtcg attaccaaag ttgacccccc ggttcccggt gaacgtgtct
     8521 tcccggaatc cattgttcgc accgtggtgc atatgatgga aagcgtggcg ctaccgggcg
     8581 gcggcggcgt gaaggcggcg attaaaggct atcgtatcgc cattaaaacc ggtaccgcga
     8641 aaaaggtcgg gccggatggt cgctacatca ataaatatat tgcttatacc gcaggcgttg
     8701 cgcctgcgag tcagccgcgc ttcgcgctgg ttgttgttat caacgatccg caggcgggta
     8761 aatactacgg cggcgccgtt tccgcgccgg tctttggtgc catcatgggc ggcgtattgc
     8821 gtaccatgaa catcgagccg gatgcgctga caacaggcga taaaaatgaa tttgtgatta
     8881 atcaaggcga gggtacaggt ggcagatcgt aatttgcgcg accttcttgc tccgtgggtg
     8941 ccagacgcac cttcgcgagc actgcgagag atgacactcg acagccgtgt ggctgcggcg
     9001 ggcgatctct ttgtagctgt agtaggtcat caggcggacg ggcgtcgata tatcccgcag
     9061 gcgatagcgc aaggtgtggc tgccattatt gcagaggcga aagatgaggc gaccgacggt
     9121 gaaatccgtg aaatgcacgg cgtaccggtc atctatctca gccagctcaa cgagcgttta
     9181 tctgcactgg cgggccgctt ttaccatgaa ccctctgaca atttacgtct cgtgggcgta
     9241 acgggcacca acggcaaaac cacgactacc cagctgttgg cgcagtggag tcaactgctt
     9301 ggcgaaacca gcgcggtaat gggcaccgtt ggtaacggcc tgctggggaa agtgatcccg
     9361 acagaaaata caaccggttc ggcagtcgat gttcagcatg agctggcggg gctggtggat
     9421 cagggcgcga ctttttgcgc aatggaagtt tcatcccacg ggctggttca acaccgtgtg
     9481 gcggcattga aatttgcggc gtcggtcttt accaacttaa gccgcgatca ccttgattat
     9541 catggtgata tggaacacta cgaagccgcg aaatggctgc tttattctgc acatcattgc
     9601 ggtcaggcga ttattaacgc cgacgatgaa gtgggccgcc gctggctggc aaaactgccg
     9661 gacgcggttg cggtatcaat ggaagatcat atcaatccga actgtcacgg acgctggttg
     9721 aaagcgaccg acgtgaacta tcacgacagc ggtgcgacca tttgctttag ctcgagttgg
     9781 ggcgatgggg aaattgaaag tcgcctgatg ggcgcattca acgtcagcaa cctgctgctg
     9841 gcgctggcga cactgctggc actcggctat ccgctggctg atttgctgaa aaccgccgcg
     9901 cgtctgcaac cggtttgcgg acgtatggaa gtgttcactg caccaggcaa accgacggtg
     9961 gtggtggatt acgcgcatac gccggatgca ctggaaaaag ccttacaggc ggcgcgcctg
    10021 cactgtgcgg gcaagctgtg gtgcgtcttt ggctgcggtg gcgatcgtga taaaggcaaa
    10081 cgtccactga tgggcgcaat tgctgaagag tttgctgacg tggtggtggt gacggacgat
    10141 aacccgcgta ccgaagagcc tcgtgccatc atcaacgata ttctggcggg aatgttagat
    10201 gccggatatg ccaaagtgat ggaaggccgt gctgaagcgg tgacttgcgc cgttatgcag
    10261 gctaaagaga atgatgtggt actggtcgcg ggcaaaggcc atgaggacta ccagattgtt
    10321 ggcaatcagc gtctggacta ctccgatcgc gtcacggtgg cgcgtctgct gggggtgatt
    10381 gcatgattag cgtaaccctt agccaactta ccgatattct caacggtgaa ctgcaaggtg
    10441 cagatattac ccttgatgct gtaaccactg acacgcgaaa actgacgccg ggctgcctgt
    10501 ttgttgccct gaaaggcgaa cgtttcgatg ctcatgattt tgccgaccag gcgaaagctg
    10561 gcggcgcagg cgcactactg gttagccgtc cgctggatat tgatctgccg cagttaatcg
    10621 tcaaggatac gcgtctggcg tttggtgaac tggctgcatg ggttcgccag caagttccgg
    10681 cgcgcgtggt tgctctgaca ggttcctccg gcaaaacctc cgttaaagag atgacggcgg
    10741 caattttaag ccagtgcggc aacacacttt atacggcagg caatctcaat aacgacatcg
    10801 gtgtaccgat gacgctgttg cgcttaacgc cggaatacga ttacgcagtt attgaacttg
    10861 gcgcgaacca tcagggtgaa attgcctgga ctgtgagtct gactcgcccg gaagcggcgc
    10921 tggtcaacaa cctggcagcg gcgcatctgg aaggttttgg ctcgcttgcg ggtgtcgcga
    10981 aagcgaaagg tgaaatcttt agcggcctgc cggaaaacgg tatcgccatt atgaacgccg
    11041 acaacaacga ctggttgaac tggcagagcg taattggctc acgcaaagtg tggcgtttct
    11101 cacctaatgc cgccaacagc gatttcaccg ccaccaatat ccatgtaacc tcgcacggta
    11161 cggaatttac cctgcaaacc cctacaggta gcgtcgatgt tctgctgccg ttgccggggc
    11221 gtcacaatat tgcgaatgcg ctggcagccg ctgcgctctc catgtctgtg ggcgcaacgc
    11281 ttgatgctat caaagcgggg ctggtaaatc tgaaagctgt tccaggccgt ctgttcccca
    11341 taaaactggc agaaaaccag ttgctgctcg acgactccta caacgccaat gtcggttcaa
    11401 tgaccgccgc tgttcaggtt ctggctgaaa tgccgggcta ccgcgtgctg gtggtgggcg
    11461 atatggcgga actgggcgct gaaagcgaag cctgccatgt acaggtgggc gaagcggcaa
    11521 aagctgctgg tattgactgc gtgttaagtg tgggtaaaca aagccatgct atcagcaccg
    11581 ccagcggcgt tggcgaacat ttttccgata aaactgcgct tatcgcgcgt cttaaatcac
    11641 tgattgctga gcaacaggta attacgattt tagttaaggg ttcacgtagt gctgccatgg
    11701 aagaggtagt acgcgcttta caggagaatg ggacatgtta gtttggctgg ccgaacattt
    11761 ggtcaaatat tattccggct ttaacgtctt ttcctatctg acgtttcgcg ccatcgtcag
    11821 cctgctgacc gcgctgttca tctcattgtg gatgggcccg cgtatgattg ctcatttgca
    11881 aaaactttcc tttggtcagg tggtgcgtaa cgacggtcct gaatcacact tcagcaagcg
    11941 cggtacaccg accatgggcg ggataatgat cctgacggcg attgtgatct ccgtgctgct
    12001 gtgggcttac ccgtccaatc cgtacgtctg gtgcgtactg gtggtgctgg taggttacgg
    12061 tgttattggc tttgttgatg attatcgcaa agtggtgcgt aaagacacca agggcctgat
    12121 tgcccgttgg aagtatttct ggatgtcggt cattgcactg ggtgttgcct tcgcgctgta
    12181 ccttgccggc aaagacacgc ccgcaacgca gttggtggtt ccgttcttta aagatgtgat
    12241 gccgcaactg gggctgttct acattctgct ggcttacttt gtcattgtgg gtactggcaa
    12301 cgcggtaaac ctgaccgatg gtctcgacgg tctggcaatt atgccgaccg tatttgtcgc
    12361 cggtggtttt gcgctggtgg cgtgggcgac cggcaacatg aactttgcca gctatttaca
    12421 cataccgtat ctacgacacg ccggggaact ggtcattgtc tgtaccgcga tagtcggggc
    12481 agggctgggc ttcctgtggt ttaacaccta tccggcgcag gtctttatgg gcgatgtagg
    12541 ttcgctggcg ttaggtggtg cgttaggtat tatcgccgta ctgctgcgtc aggaattcct
    12601 gctggtgatt atggggggcg tgttcgtggt agaaacgctt tccgtcatcc tgcaggtcgg
    12661 ctcctttaaa ctgcgcggac aacgtatttt ccgcatggca ccgattcatc accactatga
    12721 actgaaaggc tggccggaac cgcgcgtcat tgtgcgtttc tggattattt cgctgatgct
    12781 ggtcctgatt ggtctggcaa cgctgaaggt acgttaatca tggctgatta ccagggtaaa
    12841 aatgtcgtca ttatcggcct gggcctcacc gggctttcct gcgtggactt tttcctcgct
    12901 cgcggtgtga cgccgcgcgt tatggatacg cgtatgacac cgcctggcct ggataaatta
    12961 cccgaagccg tagaacgcca cacgggcggt ctgaatgatg aatggctgat ggcggcagat
    13021 ctgattgtcg ccagtcccgg tattgcactg gcgcatccat ccttaagcgc tgccgctgat
    13081 gccggaatcg aaatcgttgg cgatatcgag ctgttctgtc gtgaagcaca agcaccgatt
    13141 gtggcgatca ccggttctaa cggcaaaagc acggtcacca cgctagtggg tgaaatggcg
    13201 aaagcggcgg gggttaacgt tggtgtgggt ggtaatattg gcctgcctgc gttgatgctg
    13261 ttggatgatg agtgcgaact gtacgtgctg gaactgtcga gtttccagct ggaaaccact
    13321 tccagcttac aagcggtggc ggcgaccatt ctgaacgtga ctgaagatca tatggatcgc
    13381 tatccgtttg gtttacaaca gtatcgtgca gcaaaactgc gcatttacga aaacgcaaaa
    13441 gtttgcgtgg ttaatgctga tgatgcctta acaatgccga ttcgcggtgc ggatgaacgc
    13501 tgcgtcagct ttggcgtcaa catgggcgac tatcacctga atcatcagca gggcgaaacc
    13561 tggctgcggg tgaaaggcga gaaagtgctg aacgtgaaag aaatgaaact ttccgggcag
    13621 cataactaca ccaatgcgct ggcggcgctg gcgctggcag atgccgcagg gttaccgcgt
    13681 gccagcagcc tgaaagcgtt aaccacattc actggtctgc cgcatcgctt tgaagttgtg
    13741 ctggagcata acggtgtgcg ctgggttaac gattcaaaag cgaccaacgt cggcagtacg
    13801 gaagcggcgc tgaatggcct gcatgtagac ggcacgctgc atttgttgct gggtggcgat
    13861 ggtaaatcgg cggactttag cccactggcg cgttacctga atggcgataa tgtacgtctg
    13921 tattgtttcg gtcgggacgg cgcgcagctg gcggcgctac gcccggaagt ggcagaacaa
    13981 accgaaacca tggaacaggc gatgcgcttg cttgctccgc gtgttcagcc gggcgatatg
    14041 gttctgctct ccccggcctg tgccagcctt gatcaattca agaactttga acaacgaggc
    14101 aatgagtttg cccgtctggc gaaggagtta ggttgatgcg tttatctctc cctcgcctga
    14161 aaatgccgcg cctgccagga ttcagtattc tggtctggat ctccacggcg ctaaagggct
    14221 gggtgatggg ctcgcgggaa aaagataccg acagcctgat catgtacgat cgcaccttac
    14281 tgtggctgac cttcggcctc gcggcgattg gctttatcat ggtgacctcg gcgtcaatgc
    14341 ccatagggca acgcttaacc aacgatccgt tcttcttcgc gaagcgtgat ggcgtctatc
    14401 tgatcctggc attcattctg gcgatcatta cgctgcgtct gccgatggag ttctggcaac
    14461 gctacagtgc cacgatgctg cttggatcta tcatcctgct gatgatcgtt ctggtagtgg
    14521 gtagctcggt taaaggggca tcgcgttgga tcgatctcgg tttgctgcgt atccagcctg
    14581 cggagctgac aaaactgtcg ctgttttgct atatcgccaa ctatctggtg cgtaaaggcg
    14641 acgaagtacg taataacctg cgcggctttc tgaaaccgat gggcgtaatt ctggtgttgg
    14701 ctgtgttact gctggcacag ccagaccttg gtacggtggt ggtgttgttt gtgactacgc
    14761 tggcgatgtt gttcctggcg ggagcgaaat tgtggcagtt cattgccatt atcggtatgg
    14821 gcatttcagc ggttgtgttg ctgatcctcg ccgaaccgta ccgtatccgc cgtgttaccg
    14881 cattctggaa tccgtgggaa gatccctttg gcagcggcta tcagttaacg caatcgttga
    14941 tggcgtttgg tcgcggtgaa ctgtggggac aaggtttagg taactcggta caaaaactgg
    15001 agtatctgcc ggaagcgcac actgacttta ttttcgccat tatcggcgaa gaactgggat
    15061 atgtcggtgt ggtgctggca cttttaatgg tattcttcgt cgcttttcgc gcgatgtcga
    15121 ttggccgcaa agcattagaa attgaccacc gtttttccgg ttttctcgcc tgttctattg
    15181 gtatctggtt tagttttcag gcgctggtta acgtaggcgc ggcggcgggg atgttaccga
    15241 ccaaaggtct gacattgccg ctgatcagtt acggtggttc gagcttactg attatgtcga
    15301 cagccatcat gatgctgttg cgtattgatt atgaaacgcg tctggagaaa gcgcaggcgt
    15361 ttgtacgagg ttcacgatga gtggtcaagg aaagcgatta atggtgatgg caggcggaac
    15421 cggtggacat gtattcccgg ggctggcggt tgcgcaccat ctaatggctc agggttggca
    15481 agttcgctgg ctggggactg ccgaccgtat ggaagcggac ttagtgccaa aacatggcat
    15541 cgaaattgat ttcattcgta tctctggtct gcgtggaaaa ggtataaaag cactgatagc
    15601 tgcgccgctg cgtatcttca acgcctggcg tcaggcgcgg gcgattatga aagcgtacaa
    15661 acctgacgtg gtgctcggta tgggcggcta tgtatcaggt ccaggtggtc tggccgcgtg
    15721 gtcgttaggc attccggttg tacttcatga acaaaacggt attgcgggct taaccaataa
    15781 atggctggcg aagattgcta ccaaagtgat gcaggcgttt ccaggtgctt tccctaatgc
    15841 ggaagtggtg ggtaacccgg tgcgtaccga tgtgctggcg ctgccgttgc cgcagcaacg
    15901 tttggctgga cgtgaaggtc cggttcgtgt gttggtagtg ggtggttccc agggcgcacg
    15961 cattcttaat cagacaatgc cgcaggttgc tgcgaaactg ggtgattcag tcactatctg
    16021 gcatcagagc ggcaaaggtt cgcaacaatc cgttgaacag gcgtatgccg aagtggggca
    16081 accgcagcat aaagtgacgg aatttattga tgatatggcg gcggcgtatg cgtgggcgga
    16141 tgtcgtcgtt tgccgctccg gtgcgttaac ggtgagtgaa atcgccgcgg caggactacc
    16201 ggcgttgttt gtgccgtttc aacataaaga ccgtcagcaa tactggaatg cgctaccgct
    16261 ggaaaaagcg ggcgcagcca aaattatcga gcagtcacag cttagcgtgg atgctgtcgc
    16321 gaacaccctg gccgggtggt cgcgagaaac cttattaacc atggcagaac gcgcccgcgc
    16381 tgcatccatt ccggatgcca ccgagcgagt ggcaaatgaa gtgagccggg ctgcccgggc
    16441 gtaattgtag cgatgccttt tgcatcgtat gaatttaaga agttaatggc gtaaagaatg
    16501 aatacacaac aattggcaaa actgcgttcc atcgtgcccg aaatgcgtcg cgttcggcac
    16561 atacattttg tcggcatcgg tggtgccggt atgggcggta ttgccgaagt tctggccaat
    16621 gaaggttatc agatcagtgg ttccgattta gcgccaaatc cggtcacgca gcagttaatg
    16681 aatctgggag cgacgattta tttcaaccat cgcccggaaa acgtacgtga tgccagcgtg
    16741 gtcgttgttt ccagcgcgat ttctgccgat aacccggaaa ttgtcgcagc tcatgaagcg
    16801 cgtattccgg tgatccgtcg tgccgaaatg ctggctgagt taatgcgttt tcgtcatggc
    16861 atcgccattg ccggaacgca cggcaaaacg acaaccaccg cgatggtttc cagcatctac
    16921 gcagaagcgg ggctcgaccc aaccttcgtt aacggcgggc tggtaaaagc ggcgggggtt
    16981 catgcgcgtt tggggcatgg tcggtacctg attgccgaag cagatgagag tgatgcatcg
    17041 ttcctgcatc tgcaaccgat ggtggcgatt gtcaccaata tcgaagccga ccacatggat
    17101 acctaccagg gcgactttga gaatttaaaa cagactttta ttaattttct gcacaacctg
    17161 ccgttttacg gtcgcgcggt gatgtgtgtt gatgatccgg tgatccgcga attgttaccg
    17221 cgtgtggggc gtcagaccac gacttacggc ttcagcgaag atgccgacgt gcgtgtagaa
    17281 gattatcagc agattggccc gcaggggcac tttacgctgc tgcgccagga caaagagccg
    17341 atgcgcgtca ccctgaatgc gccaggtcgt cataacgcgc tgaacgccgc agctgcggtt
    17401 gcggttgcta cggaagaggg aattgacgac gaggctattt tgcgtgcgct ggagagcttc
    17461 caggggacgg ggcgccgttt cgatttcctc ggtgaattcc cgctggagcc agtgaatggt
    17521 aaaagcggta cggcaatgct ggtcgatgac tacggccacc acccgacgga agtggacgcc
    17581 actattaaag cggcgcgtgc aggctggccg gataaaaacc tggtaatgct gtttcagccg
    17641 caccgtttta cccgtacgcg cgacctgtat gatgatttcg ccaatgtgct gacgcaggtt
    17701 gataccctgt tgatgctgga agtgtatccg gctggcgaag cgccaattcc gggagcggac
    17761 agccgttcgc tgtgtcgcac aattcgtgga cgtgggaaaa ttgatcccat tctggtgccg
    17821 gacccggcgc aggtagccga gatgctggca ccggtattaa ccggtaacga cctgattctc
    17881 gttcaggggg ctggtaatat cggaaaaatt gctcgttctt tagctgaaat caaactgaag
    17941 ccgcaaactc cggaggaaga acaacatgac tgataaaatc gcggtcctgt tgggcgggac
    18001 ctccgctgag cgggaagttt ctctgaattc tggcgcagcg gtgttagccg ggctgcgtga
    18061 aggcggtatt gacgcgtatc ctgtcgaccc gaaagaagtc gacgtgacgc aactgaagtc
    18121 gatgggtttt cagaaagtgt ttatcgcgct acacggtcgc ggcggtgaag atggtacgct
    18181 gcagggcatg ctcgagctga tgggcttgcc ttataccggc agcggagtga tggcatctgc
    18241 gctttcaatg gataaactac gcagcaaact tctgtggcag agtgccggtt taccggtcgc
    18301 gccgtgggta gcattaaccc gcgcagagtt tgaaaaaggc cttaacgata agcagttagc
    18361 agaaatttct tctctgggtt tgccggtaat cgttaagccg agccgcgaag gttccagtgt
    18421 gggaatgtca aaagtagtag cagaaaatgc tctacaagat gcattaagat tggcatttca
    18481 gcacgatgaa gaagtattga ttgaaaaatg gctaagtggg ccggagttca cggttgcgat
    18541 actcggtgaa gaaattttac cgtcaatacg tattcaaccg gccggaacct tctatgatta
    18601 tgaggcgaag tatctctctg atgagacaca gtatttctgc cccgcaggtc tggaagcgtc
    18661 acaagaggcc aatttgcagg cattagtgct aaaagcatgg acgacgttag gttgcaaagg
    18721 atggggacgt attgacgtta tgctggacag cgatggacag ttttatctgc tggaagccaa
    18781 tacctcaccg ggtatgacca gccacagtct ggtgccgatg gcggcacgtc aggcaggtat
    18841 gagcttctcg cagttggtag tacgaattct ggaactggcg gactaatatg tcgcaggctg
    18901 ctctgaacac gcgaaatagc gaagaagagg tttcttctcg ccgcaataat ggaacgcgtc
    18961 tggcggggat ccttttcctg ctgaccgttt taacgacagt gttggtgagc ggctgggtcg
    19021 tgttgggctg gatggaagat gcgcaacgcc tgccgctctc aaagctggtg ttgaccggtg
    19081 aacgccatta cacgcgtaat gacgatatcc ggcagtcgat cctggcattg ggtgagccag
    19141 gcacctttat gacccaggat gtcaacatca tccagacgca aatagaacaa cgcctgccgt
    19201 ggattaagca ggtgagcgtc agaaagcagt ggcctgatga attgaagatt catctggttg
    19261 aatatgtgcc gattgcgcgg tggaatgatc aacatatggt agacgcggaa ggaaacacct
    19321 tcagcgtgcc gccagatcgc accagcaagc aggtgcttcc aatgctgtat ggcccggaag
    19381 gcagcgccaa tgaagtgttg cagggctatc gcgaaatggg gcagatgctg gcaaaggaca
    19441 gatttactct gaaggaagcg gcgatgaccg cgcgacgttc ctggcagttg acgctgaata
    19501 acgatattaa gctcaatctt ggccggggcg atacgatgaa acgtttggct cgctttgtag
    19561 aactttatcc ggttttacag cagcaggcgc aaaccgatgg caaacggatt agctacgttg
    19621 atttgcgtta tgactctgga gcggcagtag gctgggcgcc cttgccgcca gaggaatcta
    19681 ctcagcaaca aaatcaggca caggcagaac aacaatgatc aaggcgacgg acagaaaact
    19741 ggtagtagga ctggagattg gtaccgcgaa ggttgccgct ttagtagggg aagttctgcc
    19801 cgacggtatg gtcaatatca ttggcgtggg tagttgcccg tcgcgtggta tggataaagg
    19861 cggggtgaac gacctcgaat ccgtggtcaa gtgcgtacaa cgcgccattg accaggcaga
    19921 attgatggca gattgtcaga tatcttcggt atatctggcg ctttctggta agcacatcag
    19981 ctgccagaat gaaattggta tggtgcctat ttctgaagaa gaagtgacgc aagaagatgt
    20041 ggaaaacgtc gtccataccg cgaaatcggt gcgtgtgcgc gatgagcatc gtgtgctgca
    20101 tgtgatcccg caagagtatg cgattgacta tcaggaaggg atcaagaatc cggtaggact
    20161 ttcgggcgtg cggatgcagg caaaagtgca cctgatcaca tgtcacaatg atatggcgaa
    20221 aaacatcgtc aaagcggttg aacgttgtgg gctgaaagtt gaccaactga tatttgccgg
    20281 tctggcatca agttattcgg tattgacgga agatgaacgt gaactgggtg tctgcgtcgt
    20341 cgatatcggt ggtggtacaa tggatatcgc cgtttatacc ggtggggcat tgcgccacac
    20401 gaaggtaatt ccttatgctg gcaatgtcgt gaccagtgat atcgcttacg cctttggcac
    20461 accgccaagt gacgccgaag cgattaaagt tcgccacggt tgtgcgctgg gctccatcgt
    20521 tggaaaagat gagagcgtgg aagtgccgag cgtaggcggt cgtccgccgc ggagtctgca
    20581 acgtcagacc ctggcagagg tgatcgagcc acgctatacc gagctgctca atctggtcaa
    20641 cgaagagata ttgcagttgc aggaaaagct tcgccaacaa ggggttaaac atcacctggc
    20701 ggcaggcatt gtattaaccg gtggcgcagc gcagatcgaa ggtcttgcag cctgtgctca
    20761 gcgcgtgttt catacgcaag tgcgtatcgg cgcgccgctg aacattaccg gtttaacgga
    20821 ttatgctcag gagccgtatt attcgacggc ggtgggattg cttcactatg ggaaagagtc
    20881 acatcttaac ggtgaagctg aagtagaaaa acgtgttaca gcatcagttg gctcgtggat
    20941 caagcgactc aatagttggc tgcgaaaaga gttttaattt ttatgaggcc gacgatgatt
    21001 acggcctcag gcgacaggca caaatcggag agaaactatg tttgaaccaa tggaacttac
    21061 caatgacgcg gtgattaaag tcatcggcgt cggcggcggc ggcggtaatg ctgttgaaca
    21121 catggtgcgt gagcgcattg aaggtgttga attcttcgcg gtaaataccg atgcacaagc
    21181 gctgcgtaaa acagcggttg gacagacgat tcaaatcggt agcggtatca ccaaaggact
    21241 gggcgctggc gctaatccag aagttggccg caatgcggct gatgaggatc gcgatgcact
    21301 gcgtgcggcg ctggaaggtg cagacatggt ctttattgct gcgggtatgg gtggtggcac
    21361 cggtacaggt gcagcaccag tcgtcgctga agtggcaaaa gatttgggta tcctgaccgt
    21421 tgctgtcgtc actaagcctt tcaactttga aggcaagaag cgtatggcat tcgcggagca
    21481 ggggatcact gaactgtcca agcatgtgga ctctctgatc actatcccga acgacaaact
    21541 gctgaaagtt ctgggccgtg gtatctccct gctggatgcg tttggcgcag cgaacgatgt
    21601 actgaaaggc gctgtgcaag gtatcgccga actgattact cgtccgggtt tgatgaacgt
    21661 ggactttgca gacgtacgca ccgtaatgtc tgaaatgggc tacgcaatga tgggttctgg
    21721 tgtggcgagc ggtgaagacc gtgcggaaga agctgctgaa atggctatct cttctccgct
    21781 gctggaagat atcgacctgt ctggcgcacg cggcgtgctg gtaaacatca cagcgggctt
    21841 cgacctgcgt ctggatgagt tcgaaacggt aggtaacacc atccgtgcat ttgcttccga
    21901 caacgcgacc gtggttatcg gtacttctct tgacccggat atgaatgacg agctgcgcgt
    21961 aactgttgtt gcgacaggta tcggcatgga caaacgtcct gaaatcactc tggtgaccaa
    22021 taagcaggtt cagcagccag tgatggatcg ctaccagcag cacggtatgg ctccgctgac
    22081 ccaggagcag aagccggttg ctaaagtcgt gaatgacaat gcgccgcaaa ctgcgaaaga
    22141 gccggattat ctggatatcc cagcattcct gcgtaagcaa gctgattaag aattgactgg
    22201 aatttgggtt tcgaggctct ttgtgctaaa ctggcccgcc gaatgtatag tacacttcgg
    22261 ttggataggt aatttggcga gataatacga tgatcaaaca aaggacactt aaacgtatcg
    22321 ttcaggcgac gggtgtcggt ttacataccg gcaagaaagt caccctgacg ttacgccctg
    22381 cgccggccaa caccggggtc atctatcgtc gcaccgactt gaatccaccg gtagatttcc
    22441 cggccgatgc caaatctgtg cgtgatacca tgctctgtac gtgtctggtc aacgagcatg
    22501 atgtacggat ttcaaccgta gagcacctca atgctgctct cgcgggcttg ggcatcgata
    22561 acattgttat cgaagttaac gcgccggaaa tcccgatcat ggacggcagc gccgctccgt
    22621 ttgtatacct gctgcttgac gccggtatcg acgagttgaa ctgcgccaag aaatttgttc
    22681 gcattaaaga gactgttcgt gtcgaagatg gcgataagtg ggctgaattt aaaccgtaca
    22741 atggtttttc gctggatttc accatcgatt ttaaccatcc ggctattgat tccagcaacc
    22801 agcgctatgc gatgaacttc tccgctgatg cgtttatgcg ccagatcagc cgtgcgcgta
    22861 cgttcggttt catgcgtgat atcgaatatc tgcagtcccg tggtttgtgc ctgggcggca
    22921 gcttcgattg tgccatcgtt gttgacgatt atcgcgtact gaacgaagac ggcctgcgtt
    22981 ttgaagacga atttgtgcgt cacaaaatgc tcgatgcgat cggtgacttg ttcatgtgtg
    23041 gtcacaatat tattggtgca tttaccgctt ataaatccgg tcatgcactg aataacaaac
    23101 tgctgcaggc tgtcctggcg aaacaggaag cctgggaata tgtgaccttc caggacgacg
    23161 cagaactgcc gttggccttc aaagcgcctt cagccgtact ggcataacga catttatact
    23221 gtcgtataaa attcgactgg caaatctggc actctctccg gccaggtgaa ccagtcgttt
    23281 tttttgaatt ttataagagc tataaaaaac ggtgcgaacg ctgttttctt aagcactttt
    23341 acgcacaact tatcttcatt cgtgctgtgg acttcaggct ttaatgataa gatttgtgcg
    23401 ctaaatacgt ttgaatacga tcgggatggc aataacgtga gtggaatact gacgcgctgg
    23461 cgacagtttg gtaaacgcta cttctggccg catctcttat tagggatggt cgcggcgagt
    23521 ttaggtttgc ctgcactcag caatgccgcc gaaccaaacg cgcccgcaaa agcgacaacc
    23581 cgcaaccacg agccttcagc caaagttaac tttggtcaat tggccttgct ggaaacgaac
    23641 acgcgccgcc cgaattcgaa ctattccgtt gattactggc atcaacatgc cattcgcacg
    23701 gtaatccgcc atctttcctt tgcaatggca ccgcaaacgc tgcccgttgc tgaagaatct
    23761 ttgcctcttc aggcgcaaca tcttgcatta ctggatacgc tcagcgcgct gctgacccag
    23821 gaaggcacgc cgtctgaaaa gggttatcgc attgattatg cgcattttac cccacaagca
    23881 aaattcagca cgcccgtctg gataagccag gcgcaaggca tccgtgctgg ccctcaacgc
    23941 ctcagctaac aacaataaac ctttacttca ttttattaac tccgcaacgc ggggcgtttg
    24001 agattttatt atgctaatca aattattaac taaagttttc ggtagtcgta acgatcgcac
    24061 cctgcgccgg atgcgcaaag tggtcaacat catcaatgcc atggaaccgg agattgaaaa
    24121 actctccgac gaagaactga aaggaaaaac ggcagagttc cgcgcgcgtc tggaaaaagg
    24181 cgaagtgctg gaaaacttga tcccggaagc cttcgccgtg gtgcgtgaag ccagtaagcg
    24241 tgtttttggc atgcgccact tcgacgtaca gctgctcggc ggtatggttc ttaatgaacg
    24301 ctgcatcgcg gaaatgcgta ccggtgaagg taaaaccctg accgcaacgc tgcctgctta
    24361 cctgaacgca ctaaccggta aaggcgtgca cgtcgttacc gtcaacgact acctggcgca
    24421 acgtgacgcc gaaaacaacc gtccgctgtt tgaattcctt ggcctgactg tcggtatcaa
    24481 cctgccgggc atgccagcac cggcaaagcg tgaagcctac gctgctgaca tcacttacgg
    24541 tacgaacaac gaatacggct ttgactacct gcgtgacaac atggcgttca gtcctgaaga
    24601 acgtgtacag cgtaaactgc actatgcgct ggtggacgaa gtggactcca tcctgatcga
    24661 tgaagcgcgt acaccgctga tcatttctgg cccggcagaa gacagctcgg aaatgtataa
    24721 acgcgtgaat aaaattattc cgcacctgat ccgtcaggaa aaagaagact ccgaaacctt
    24781 ccagggcgaa ggccacttct cggtggacga aaaatctcgc caggtgaacc tgaccgaacg
    24841 tggtctggtg ctgattgaag aactgctggt gaaagaaggc atcatggatg aaggggagtc
    24901 tctgtactct ccggccaaca tcatgctgat gcaccacgta acggcggcgc tgcgcgctca
    24961 tgcgctgttt acccgtgacg tcgactacat cgttaaagat ggtgaagtta tcatcgttga
    25021 cgaacacact ggtcgtacca tgcaggggcg tcgctggtct gatggtctgc accaggctgt
    25081 ggaagcgaaa gaaggtgtgc agatccagaa cgaaaaccaa acgctggctt cgatcacctt
    25141 ccagaactac ttccgtctgt atgaaaaact ggcggggatg actggtactg ctgataccga
    25201 agctttcgaa ttcagctcca tctataagct ggatactgtc gttgttccga ccaaccgtcc
    25261 aatgattcgt aaagatctgc cggacctggt ctacatgact gaagcggaaa aaattcaggc
    25321 gatcattgaa gatatcaaag aacgtactgc gaaaggccag ccggtgctgg tgggtacaat
    25381 ctccatcgaa aaatcggagc tggtgtcaaa tgaactgacc aaagccggta ttaagcacaa
    25441 cgtcctgaac gccaaattcc atgccaacga agcggcgatt gttgctcagg caggttatcc
    25501 ggctgcggtg actatcgcga ccaacatggc gggtcgtggt accgatattg tgctcggtgg
    25561 tagctggcag gcagaagttg ccgcgctgga aaatccgact gcagagcaaa ttgaaaaaat
    25621 taaagccgac tggcaggtac gtcacgatgc ggtactggca gcaggtggcc tgcatatcat
    25681 cggtactgaa cgtcacgaat cccgtcgtat cgataaccag ctgcgcggtc gttctggtcg
    25741 tcagggggat gctggttctt cccgtttcta tctgtcgatg gaagatgcgc tgatgcgtat
    25801 ttttgcctcc gaccgagtat ccggcatgat gcgtaaacta ggtatgaagc caggcgaagc
    25861 cattgagcac ccgtgggtga ccaaagcgat tgccaacgcc cagcgtaaag ttgaaagccg
    25921 taacttcgac attcgtaagc aactgctgga atatgatgac gtggctaacg atcagcgtcg
    25981 cgccatttac tcccagcgta acgaactgct ggatgtcagc gatgtgagcg aaaccatcaa
    26041 cagcattcgt gaagatgtgt tcaaagcgac cattgatgcc tacattccgc cacagtcgct
    26101 ggaagaaatg tgggatattc cggggctgca ggaacgtctg aagaacgatt tcgacctcga
    26161 tttgccaatt gccgagtggc tggataaaga accagaactg catgaagaga cgctgcgtga
    26221 gcgcattctg gcgcagtcca tcgaagtgta tcagcgtaaa gaagaagtgg ttggtgctga
    26281 gatgatgcgt cacttcgaga aaggcgtcat gctgcaaacg cttgactctc tgtggaaaga
    26341 gcacctggct gcgatggact atctgcgtca gggtatccac ctgcgtggct atgcacagaa
    26401 agatccgaag caggaataca aacgtgaatc gttctccatg tttgcagcga tgctggagtc
    26461 gttaaaatat gaagttatca gcacgctgag caaagttcag gtgcgtatgc ctgaagaggt
    26521 tgaggagctg gaacaacagc gtcgtatgga agccgagcgt ttagcgcaaa tgcagcagct
    26581 tagccatcag gatgacgact ctgcagccgc agctgcactg gcggcgcaaa ccggtgaacg
    26641 aaaagtagga cgtaacgatc cttgcccgtg tggttctggt aaaaaataca agcagtgcca
    26701 tggccgcctg caataaaagc taactgttga agtaaaaggc gcaggattct gcgccttttt
    26761 tataggttta agacaatgaa aaagctgcaa attgcggtag gtattattcg caacgagaac
    26821 aatgaaatct ttataacgcg tcgcgcagca gatgcgcaca tggcgaataa actggagttt
    26881 tccggcggta aaattgaaat gggcgaaacg ccggaacagg cagtggtacg tgaacttcag
    26941 gaagaagtcg ggattacccc acaacatttt tcgctatttg aaaaactgga atatgaattc
    27001 ccggacaggc atataactct gtggttctgg ctggtcgaaa gctgggaagg ggagccgtgg
    27061 ggtaaagaag ggcaacccgg tgagtggatg tcgctggtcg gtcttaatgc cgatgatttt
    27121 ccgccagcca atgaaccggt aattgcgaaa cttaagcgtg tgtatgtcga ataaggcgtc
    27181 acgctgcatc cgacatttgc atatgatgcc tgatgcgacg ctggcgcgtt ttatcaggcc
    27241 agcatcgcat cagatagaat gtcactgctt tggctcttcg ctccagtcat cgctttcgga
    27301 aagatcgcca ctgctgggga ttcgtttttc ttcagcagcc cattctccga ggtcgatcag
    27361 ctgacaacgt ttggagcaaa atggccgaaa cgggctgatt tcaccccaca ccaccgtttt
    27421 cccgcaggtt gggcaattca ccgtaatagt ttctgacatt tttactcctt agcaacaggc
    27481 cagttcgaaa tccagacgtt ctggtacttg tccgttttca ctgtccagcg gcataaaacg
    27541 aatggcaaaa cggctcttat gaccggaaat ttgcggataa agctgtgaat cgagcgacag
    27601 attcaggcgc agcaagtcgg catcgccacc gttatcctga taaaaaccat tcaggctggt
    27661 ttgtttacgg aagggggccg actggcgaat taaatccagc accatggtaa gtgcctgggt
    27721 aagtgggttc aggctggcaa tccaggtttc tacctggctg tcgcgctgcg cctggggtag
    27781 atgcagccaa atgtgcaatg taggtaaatc aaagctgcaa cagccgcccg ggatgctcag
    27841 tcgctgacgc accagagcaa tcaaacgatc ttcacgtaga aattgcccga tacgcggcgc
    27901 ggaaattaat acgctccccg ccgcttttaa ctgctgaatt aatgcttcaa tacggctctg
    27961 gtccacgccg ggcacgccaa tccaggtctg gagtttacgt tgctgccggt caagttcttt
    28021 caacagctca gtgcggactt cgccgcgctc gaaaacatcc agtaattcgc tgacattacg
    28081 gaagaaatgc agcgcgccag cgtggtcaac gatgggtaaa ttaacggtga gttgctgaat
    28141 caaaaactca atgcgcagcc atgtacgcat tttttcattt agtggatgtt caaaaaggac
    28201 ctgggtctgc attacggttt ttcctgtgag acaaactgcg acgcaagctg caaatagtgt
    28261 gcgtgcaggc gggcaacatc cgatgcgata gcatccggtg cgccgttatt atcaatgacg
    28321 tcatctgcca cggcaaggcg agcttcgcgc gttgcctgag cagcaaggat ttgttcgaca
    28381 tgctcgcgag ttacatcgtc gcgctgcatg gtgcgcttaa gttgcgtttc tgggctgaca
    28441 tccaccacca gcactcgatt cgctttttta tacagtgagt tttctaccag caatggcaca
    28501 acccatagta cataggggga agtagcttgc tggatctggt gttgcgtctc ttgctgaatc
    28561 agcggatgca gcagggcgtt aagccagttt ttctcttccg ggttggcgaa gatccgctcg
    28621 cgcaaggccc ggcgctgcaa tgttccatca gcagcaatca tgttagcgcc aaagtgatca
    28681 gcaatggcat gtagcgcagg tgcacctggt tcaaccacct gacgcgcaat aatatcggca
    28741 tcaatgacgt taattccgag atcagcaaac gcattggcaa cggtactctt gccactgcca
    28801 atgcctcccg ttaaggcaac tatatacctc ataatttata ttcccgggaa ttcatcatga
    28861 ttatcaaaac gttaaaaatg agcgcacgaa agcgaaattg atgaaacgtt cgctcactat
    28921 ttaccaggta aatttatggg attgtagcgt aaaaaaagac aatttcgcag tcttgcgccg
    28981 cattgattag tgcgtatgat aacgtcactg gagttgcgct cttaccctta tagccattaa
    29041 ccccaggaat ccgcacatgc gtattgaaga agatctgaag ttaggtttta aagacgttct
    29101 catccgccct aaacgctcca ctcttaaaag ccgttccgat gttgaactgg aacgtcaatt
    29161 caccttcaaa cattcaggtc agcgctggtc cggcgtgcca attatcgccg ccaatatgga
    29221 caccgtaggc acattttcta tggcctctgc gctggcttct tttgatattt tgactgctgt
    29281 gcataaacac tattctgtcg aagagtggca agcgtttatc aacaattctt ccgctgatgt
    29341 gctgaaacat gtgatggttt ctaccggcac gtctgatgcg gatttcgaaa aaactaaaca
    29401 gattctcgac ctgaacccgg cattaaactt cgtttgtatt gacgtggcga atggttattc
    29461 cgaacacttc gtgcagttcg ttgcgaaagc gcgtgaagcg tggccgacca aaaccatttg
    29521 tgctggcaac gtagtgactg gtgaaatgtg tgaggagctt atcctctccg gtgctgatat
    29581 cgttaaagtt ggcattggcc caggttctgt ttgtacaact cgcgtcaaaa caggcgtcgg
    29641 ttatccgcaa ctttctgcgg tgatcgaatg tgccgatgct gcgcatggtc tgggcggaat
    29701 gatcgtcagc gacggtggct gcaccacgcc gggcgatgtc gcgaaagcct ttggcggcgg
    29761 tgccgatttc gtcatgcttg gcggcatgct ggcgggccac gaagagagcg gcggtcgcat
    29821 cgttgaggag aacggcgaga aatttatgct gttctacggc atgagctcag agtctgcgat
    29881 gaaacgtcac gttggcggtg ttgcggaata tcgcgcagca gaaggtaaaa ccgttaagct
    29941 gccgctgcga ggcccggttg aaaataccgc gcgtgatatt ttgggcggcc tgcgttcagc
    30001 ttgtacatac gttggggctt cacgcctgaa agaactgacc aagcgcacca catttatccg
    30061 tgtgcaggaa caagaaaacc gcatcttcaa caacctgtaa tataccaacg ctggcgtgga
    30121 gcaacacgcc agcgttatcc cattccactc atcgcatcgc ctaaatggaa aattggcaga
    30181 tacattgcca ccaccagcgt accgataatt cctcccgtta tgatcagcaa cgccggttcc
    30241 agtaaggctg cgaggttatc cgccagcgcc attgtgttat cccgatgatg atgggcgagg
    30301 ttgtctaaca tgagatccag cgagccggat gcctctcctg ttctcactaa ttgcaaacag
    30361 agcgggctaa actcaccggc attttttagc gccagccaga tggggtgacc gttactgata
    30421 tcgtgctgga tttgtgtcag aagttgcacc cagtacggac agcgcattgt ttctctgacg
    30481 ctctcaacgc cctgtaaaaa agaaatgcct gcactttgtg tcagcgtcag aatcgtaaag
    30541 atctgcgtga gtttttgtcc ccgcatcagt gaacccataa tcgggatgcg taacagtaat
    30601 ttctgccgtg cgataagcct ggttgggtgg cgcatcagca gcttattggc tatcgccagc
    30661 agaaagccga atagcaccag caaccaaccc cattcgccac taaaacttgc cagcgtcatg
    30721 atcccctgcg ttagcgccgg tagcggagtg ttaaaggtct tatagatagc ggcaaactcc
    30781 ggcagaacaa aatgcagcat tgccacaacc accatgattg ccatcgctaa aatgataatg
    30841 ggataacgta acgctgattt cactttgtcg gtcaactgac gctgggcttt ttgctgacgc
    30901 gccagttcaa agcagcattc atccagctta ccggtcagtt cacctgtgcg gatcatcgcc
    30961 tgatagagcg gcggaaatac ctctgaccag ggtaataagg cattggaaaa ggcaacgccc
    31021 tgttcaagat cgtgcgccag tgattgcagc aacgcttgcc actgcttact gggatgctgt
    31081 tccgccagca gagccagccc ttcagaaagc gttaacccgg ctttgagtag cgtcgccagt
    31141 tgatgaatga cttccgcgct tttatctcct cgccactgcg cagaattgat ggcgattcgc
    31201 ttcaggctta gtggggtaac catctgttgc tgtagtgcca tgagcagcaa agcacggctc
    31261 tctgcccata gcatcccatc ttgcgcattg ccgtcgccgg ttatgccacg ccagcgccag
    31321 agttgcttac tcgccatgcg gcatccccaa tacgcggatt aactcttcaa aggtggttaa
    31381 gccttgctcc acagccaggc agccgttttc aaaaagcgtt cgcatacccg cctgtcgggc
    31441 gtgcgtttcc agcgattcaa cgtcggtatt agcggaaata agctgacgta tgaccggtgt
    31501 tatgggcaga acttcaaata aggccgtgcg accataaaaa ccgtggtagc aatgtacaca
    31561 accgggtgcc tgtcagtggg gcagcggcga cggccataca ttgtctggaa tatggatggg
    31621 ctccccttgc tgccggcgac aatgcgggca aagtttgcgt accagacgct gggctattac
    31681 cagcgtaagc gccgatgata gcatccagcg ggcgactccc atttgctgta aacgtaccag
    31741 cgtttcgcag gtggaattag tgtgtagggt agacaacacc aggtgaccgg tttgcgcggc
    31801 ttttatggca atttctgccg tttcgccatc gcggatctct ccgatcatga tgacgtcagg
    31861 atcctggcgc aataacgcac gcaaaacgcc ctgaaaggtg agtccggcac gcgaatggat
    31921 ttgcgtctgg tttaatccgg ctatggggat ctcaaccgga tcttcgacgc tacaaatatt
    31981 aatgtcagcg gtattcagcg tttgcagggc actataaagc gtgaccgttt tgccgctgcc
    32041 tgtagggcca gttaccagca ctagtccctg tggttgttgc aaggcatgag caaagtccac
    32101 cagttgtgac ggctgcattc caagcgtgtt aacatccagt gcctggttca cctgctgtaa
    32161 caaccttaat accacctttt caccaccccg acatgctaag gtcgcaatac gaaatgagac
    32221 ggcgtttcct gccagttcga cagtgaattg cccgtcctgc ggcaggcgat gttccgcaat
    32281 atccaggttt cccagcactt ttaatctggc ggttaatgcg actccggcat ccggtgaaac
    32341 gtccggtaaa ggatgcaata cgccgtcgat acgcaagcgg atgcggtagg cattgtccgc
    32401 tggttcgata tgaatatcag acgcgcgttg ttctagcgca gattgtaacg ttcgagtcag
    32461 caactctgct ttgggctgat gcttctcctg aacagctacg ggcaatgtct gttgtgtgcg
    32521 actggcgtga ccttccattt gttggcgcgt ccagcaggtg atctcaatac gtttggtggt
    32581 agcgaaatgc aatgcgtcca gtagctcatg cgaaggtgca tcgactaccg caacatgaac
    32641 cacctcttcg ctggcatcca gcaagactcc ctgataacgc agacacaggg cagtgagctg
    32701 tggaatattc attgccgctc cttagttggc gtcatcaaag cggaagacat cttcgcaggc
    32761 ttgctgcaat gcgctgtcac tttgaatatt gcagttacgc gtccagccgg tgacgccgtt
    32821 tgcgttatcc caacccggtg tcatgacgac gcttagccca ttgagacttt cttgcccggt
    32881 cagcgacacc acgccctttg ccacactcat ggctgaaaca tagcgggtgg tggtaggcga
    32941 aggaatgcca ttgctgccac cgtcgcaggt atttaatcca ccatgttcca gcgcgcacaa
    33001 ctctacggcg gtacggtaag gcacaaaggt ttgtagcatg tcggtgagtg cggctttgcg
    33061 caggtagttt tgataagcgg gaataccaat ggcgcttaaa atggcaatga tgccaataac
    33121 caccatcagt tcaataagtg taaaaccgcg ttgcttgtcc atctgtttcg ctccttgatt
    33181 tggttggcgc tactttggca aacgccatca gcacaagcga ggggcaaaaa acgaaacggg
    33241 aaagcagctt ccgaggtttt ttacttcgtt gcagcgaaag acaagaaatt tgcgaggcgt
    33301 tacgaagaaa gttggggaag gggagattta tccgcccgcg atggagcgga taaatctgtt
    33361 agcaattagc gaaaacgcat tgaaaggtcg agtgcctgta cgtgtttagt tagtgcacca
    33421 acggagataa agtccacgcc cgtttcggca aattcgcgca gtgttttgtc agtgacgttg
    33481 ccagacactt ccagtagcgc cttgccgttg gtgcgtttga cggcttcgcg catctgttct
    33541 gtttcgaagt tatccagcat gatgatatcg gcacctgctt tcagggcttc atcaagttct
    33601 tccagattct ctacttcgac ttctactggc gcatccgggt gcaaccagga cgctttttcg
    33661 accgcctgcc gcactgagcc ggaggcaata atatggtttt ctttgatcag gaaggcatca
    33721 gaaagcccca gacggtgatt cgctccgccg ccgcaaagta ccgcgtattt cagagctgaa
    33781 cgcaggccgg gtaaggtttt gcgcgtatcc aacagctgcg tgttggtgcc ttccagtaat
    33841 tcgacatagt ggcgtacctt actggcaact cctgaaaggg tttgcacaaa attaagcgca
    33901 gtgcgttcgc ccgttaacag cacgcgagat gggccttcaa gttcgaacaa gggttgattg
    33961 gcgttgatga catcgccgtc atccacatgc cagattatgg tgacatcgtc gcctgccagt
    34021 tgaataaaca cctcttcaac ccagcgtttg ccgcaaaata cgccattctc gcgggtgatc
    34081 actgtggcat gagagcgaga gttttccggt aaaagttttg ccgtaatgtc attgttggca
    34141 tcgactgttc cgcctaaatc ttcccgcagc gcctgggcca ccgcgccggg gatatcgaga
    34201 ttaatgcgtt ccagcagctc gtcacgtcgg gtgtcagggt tatagcggcg aggcggcatg
    34261 ttaaaactcc agatagctaa cgaatcataa ggtagaaaca tgctactctg aaccgggtat
    34321 tagcaccaca tataaggaga tcctgcatgt tgttagaaca ggggtggctg gctggcgcgc
    34381 gccgcgttcc ctcaccacat tacgattgcc gcccggatga cgaaacaccc accctgctgg
    34441 tggtgcacaa tattagcctg ccgccaggcg agtttggcgg tccgtggatc gacgcattat
    34501 tcactggaac tattgatccg caggcgcatc ctttctttgc ggagatcgcc catttgcgcg
    34561 tctccgctca ctgtttgatt cgccgtgatg gtgaaatagt ccagtatgtt cctttcgata
    34621 aacgagcctg gcatgcggga gtctctcagt atcaggggcg cgaacgctgc aatgattttt
    34681 ctattgggat tgagctggaa ggcaccgata cgctggcgta taccgatgcg cagtatcaac
    34741 agcttgcggc ggttacacgg gcactgattg atcgctatcc ggatatcgct aataacatga
    34801 cgggccattg tgatattgcg ccggatcgga aaaccgatcc cggtcctgca tttgattggg
    34861 cacggtttcg tgcgctggtc agcaaggaga caacatgacg ctatttacaa ccttactggt
    34921 gttaattttc gagcgcctgt ttaagttggg cgagcactgg cagcttgatc atcgtcttga
    34981 agcgttcttt cggcgggtga aacatttttc tctcgggcgc acgttatgca tgaccattat
    35041 tgcgatgggc gtgacttttt tactgttacg cgcattgcag ggtgtattgt tcaacgttcc
    35101 cacgttgctg gtgtggctgc tgattggttt gctgtgtatt ggcgcaggta aagttcgtct
    35161 tcattatcat gcttatctga cagctgcttc acgtaatgat agccatgccc atgccacgat
    35221 ggctggcgaa ctcaccatga ttcacggcgt cccggcaggc tgcgatgaac gtgagtattt
    35281 gcgtgagctg caaaatgcat tgctgtggat taactttcgt ttttatcttg ctccgctgtt
    35341 ctggctgatt gtggggggaa cctggggacc cgttacgctg atggggtatg cgtttttgcg
    35401 tgcatggcaa tactggctgg cgcgatacca gacgccgcat catcgtttac agtccggcat
    35461 tgatgccgtg cttcatgcac tggattgggt gccggttcgt cttgcgggtg tggtatatgc
    35521 cttgatcggt catggtgaga aagcgttacc ggcctggttt gcttcgctgg gtgatttcca
    35581 tacttcgcaa tatcaggtat taacgcgtct ggcacagttc tctctggcgc gtgaaccgca
    35641 tgtcgataag gtggagacgc caaaggccgc ggtttcaatg gcgaagaaaa cctcgttcgt
    35701 ggtcgtggtg gtaattgcgc tactgacgat ttacggggcg ttggtgtaaa gattattgcc
    35761 ctcaccctgc acgggtgagg gcgtagagag attaatgcgc ttttacggct ttggcggttt
    35821 tctctttaaa cagatagccg atacctaaca cgatcagcca taccgggatc aggtataccg
    35881 aaatcgccat tcctggggtc atcagcataa tcaccagtac cgccgccata aacagcaggc
    35941 agatccagtt acccagcgga taaagcaggg cagggaagcg agttaccacg ccttgttctt
    36001 gtttggcacg acggaatttc atatgcgcca gactgatcat cgcccagttg atgaccagtg
    36061 cagataccac cagcgccatt aacagtccga aagcggactc tggggcaagg tagttaatca
    36121 gtacgcacaa tgccgtaacc agcgcagaca ccagaatagt gttaaccggt acgccgcgtt
    36181 tatcgacaga cgccagcgct tttggcgcgt tcccttgttg tgccagaccg aacagcatac
    36241 ggctgttgca atatacgcag ctgttgtaca cggagagcgc agcagtcagt accacgatat
    36301 tcagcgcatt cgctacaaag gtatcgccta actcgtggaa gatcagcaca aacggactgg
    36361 tatcggcggt aacgcgggtc cacggcatta gtgagagcag aacggctaac gagccaatat
    36421 agaaaatcag gatgcggtag ataacctggt tagttgcttt cgggatactt tgctccgggt
    36481 tatcagcttc tgctgcggtg atccccacca gttccagacc accgaaagag aacatgataa
    36541 tcgccatcat catcaccaga ccggtgaagc cgtgtggcag gaaaccaccc tgatcccaca
    36601 ggttgctaac gctcgcctgc gggccgccgt tgccgctgaa tagcagccag gcgccgaaga
    36661 tgatcatcgc taccaccgcg ataactttga taatggcaaa ccagaactcc atctcgccaa
    36721 acacttttac gtttgtcagg ttgatggcgt tgatcaccac aaagaacacg gcggcagaaa
    36781 cccaggttgg gatttccgga taccagaact gaatgtattt acccacggca gtcagctctg
    36841 ccatggcaac taaaacgtac agtacccagt agttccagcc agaggcgaaa ccggcaaaac
    36901 tgccccagta tttataagca aagtggctaa aggagcctgc gacaggttct tcgaccacca
    36961 tttcacctag ctgacgcatg atcagaaagg cgataaaacc agcaatggcg taacccagga
    37021 taatccctgg ccctgcggac tgtattacgg aggcgctacc caggaatagc cctgtcccta
    37081 tcgcgccacc cagcgcgata agctgaatat ggcggttttt aaggccgcgc tttagctgct
    37141 cgccgtgctg ttgaccttcc attatgaaac ctcgtgttgt gttgtttttt tgaactacgc
    37201 agcaatgcgt gtgtaatttt gtaattccgt ttgttgtatt ggtttcttta cattttatgt
    37261 aactgaatta tgatgatagt actttcaact atcacaagat aatggtatac gcgcgagaat
    37321 gcacctgctt tatgtagatg tgttgatttt ctggataaaa aaaaagcaat tgtaagtttt
    37381 tcatcacatt taatagatac tttaagtctg ataacatact gttttaacta gctatatacc
    37441 ggatttgtct gcctgctgaa caccatgcct tagccaccag cacaataatc ttaca
//
LOCUS       DAFGPF010000042        36784 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFGPF010000042 DAFGPF010000000
VERSION     DAFGPF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36784
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.042"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(139..891)
                     /gene="yecC"
                     /locus_tag="LSX49_002305"
     CDS             complement(139..891)
                     /gene="yecC"
                     /locus_tag="LSX49_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HBL7168706.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGVAKALFADPQQPRTRQFLEKFLLQ"
     gene            complement(888..1556)
                     /gene="tcyL"
                     /locus_tag="LSX49_002306"
     CDS             complement(888..1556)
                     /gene="tcyL"
                     /locus_tag="LSX49_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HBL7168707.1"
                     /translation="MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            complement(1571..2557)
                     /gene="dcyD"
                     /locus_tag="LSX49_002307"
     CDS             complement(1571..2557)
                     /gene="dcyD"
                     /locus_tag="LSX49_002307"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HBL7168708.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEVAVNISSVVVASGSAGTHAGLAVGLEQLMPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            complement(2662..3462)
                     /gene="tcyJ"
                     /locus_tag="LSX49_002308"
     CDS             complement(2662..3462)
                     /gene="tcyJ"
                     /locus_tag="LSX49_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7168709.1"
                     /translation="MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTADDLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
     gene            complement(3550..4101)
                     /gene="fliZ"
                     /locus_tag="LSX49_002309"
     CDS             complement(3550..4101)
                     /gene="fliZ"
                     /locus_tag="LSX49_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HBL7168710.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIV
                     NKIEISRLDTLLDENGWQVEQQSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGTVREYVVRLRRLGNHLHEQNISLDQLQDGFLDEILAPWLPSTSTNNYRIALRKYQ
                     HYQRQTCTGLVQKSSSLPASDIY"
     gene            complement(4147..4866)
                     /gene="fliA"
                     /locus_tag="LSX49_002310"
     CDS             complement(4147..4866)
                     /gene="fliA"
                     /locus_tag="LSX49_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HBL7168711.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDNNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            complement(5030..6079)
                     /locus_tag="LSX49_002311"
     CDS             complement(5030..6079)
                     /locus_tag="LSX49_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079755.1"
                     /note="structural flagella protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin FliC"
                     /protein_id="HBL7168712.1"
                     /translation="MAQVINTNSLSLITQNNINKNQSALSTSIERLSSGLRINSAKDD
                     AAGQAIANRFTSNIKGLTQAARNANDGISLAQTAEGALSEINNNLQRIRELTVQASTG
                     TNSDSDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKNDSMKIQIGANDNQTISIGL
                     QQIDSTTLNLKGFTVSGMADFSAAKLTAADGTAIAAADVKDAGGKQVNLLSYTDTASN
                     STKYAVVDSATGKYMEATVVITGTAAAVTVGAAEVAGAATADPLKALDAAIAKVDKFR
                     SSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLS
                     KANQVPQQVLSLLQG"
     gene            6327..7742
                     /gene="fliD"
                     /locus_tag="LSX49_002312"
     CDS             6327..7742
                     /gene="fliD"
                     /locus_tag="LSX49_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBL7168713.1"
                     /translation="MASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKL
                     SAYGTLKSALESFQTANTALNKADLFTATSTTSSSSAFSATTTGSAIAGKYTISVSQL
                     AQAQTLTTKNSQKDSKAAIATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNA
                     KAGVSASIINVGNGEYRLSITANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGM
                     IESVTAQNAKLTVNNVEIENSSNTISDSLEDITLNLNDVTTGNQTLTISKDTSKAENA
                     VKAWVDAYNTLQDTFSSLTKYTAVDAGAESQDSSNGALLGDSTLRTIQTQLKTLLANT
                     HSSSNYKTLAQIGITSDASTGKLEIATDKLQTALKNDAAGIGEMFIGDGKSTGVTTGI
                     SSNLTSWLSSTGIIQAAKDGVSKTLNNLTDQYNAASERIDTLMTRYKAQFTQLDVLMN
                     SLNSTSSYLTQQFDTSNSNSK"
     gene            7758..8168
                     /gene="fliS"
                     /locus_tag="LSX49_002313"
     CDS             7758..8168
                     /gene="fliS"
                     /locus_tag="LSX49_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBL7168714.1"
                     /translation="MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV"
     gene            8168..8533
                     /gene="fliT"
                     /locus_tag="LSX49_002314"
     CDS             8168..8533
                     /gene="fliT"
                     /locus_tag="LSX49_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HBL7168715.1"
                     /translation="MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKIKQLLQIRMDELAKLVGQSSVQKSV
                     LSAYGDQGGFVLAPQDNLF"
     gene            8611..10098
                     /gene="amyA"
                     /locus_tag="LSX49_002315"
     CDS             8611..10098
                     /gene="amyA"
                     /locus_tag="LSX49_002315"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HBL7168716.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTIHLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(10132..10545)
                     /locus_tag="LSX49_002316"
     CDS             complement(10132..10545)
                     /locus_tag="LSX49_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL7168717.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLTGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            10732..11937
                     /gene="yedE"
                     /locus_tag="LSX49_002317"
     CDS             10732..11937
                     /gene="yedE"
                     /locus_tag="LSX49_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HBL7168718.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            11934..12167
                     /gene="yedF"
                     /locus_tag="LSX49_002318"
     CDS             11934..12167
                     /gene="yedF"
                     /locus_tag="LSX49_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBL7168719.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            12276..12773
                     /locus_tag="LSX49_002319"
     CDS             12276..12773
                     /locus_tag="LSX49_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000334561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL7168720.1"
                     /translation="MCGRFAQSQTREDYLAFLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSHMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQAVFIAAIGSTPFERGDEAGRSFCKPAQGLSVTVAMA
                     VRANL"
     gene            complement(12655..12984)
                     /locus_tag="LSX49_002320"
     CDS             complement(12655..12984)
                     /locus_tag="LSX49_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7168721.1"
                     /translation="MKRLQAFKFRLRPGGQQERGMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDPERAYKNFFRLRHHAQT
                     VCYLSRL"
     gene            13007..13531
                     /gene="tnpA"
                     /locus_tag="LSX49_002321"
     CDS             13007..13531
                     /gene="tnpA"
                     /locus_tag="LSX49_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL7168722.1"
                     /translation="MKKETDIRRGRHCVFLKHVHLVFVTKYRRQIFDHDATEKLRTYF
                     SNVCADFEAERVEMDGGPDHVHLLINYPPKLAISSLVNSLKGVSSRLLRRDRPDIAVR
                     YYDKGVLWSPGYFVSSCILTYQLDLITTISVPNRISNVISIPLIIPSTSCNFPTLELH
                     IVQTPDAKKSHVHF"
     gene            complement(13688..14485)
                     /locus_tag="LSX49_002322"
     CDS             complement(13688..14485)
                     /locus_tag="LSX49_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7168723.1"
                     /translation="MLAKDKTNLKIEEIRMHKHHEIHRVKPLMPALCRIRQGKKVINW
                     ETHSLTVDNNQIILFPCGYEFYIANYPEAGLYLAEMLCYPIDLIEKFQKFYAITDQIR
                     NTTGFCLPQNPELIYCWEQLKTSISRGFSTQIQEHLAMGVLLSLGAHHVNCLLLSDSK
                     QSLISRCYNLMLSEPGTKWTANKVARYLYISVSTLHRRLASEGVSFQSILDDVRLNNA
                     LSAIQTTVKPISEIARENGYKCPSRFTERFHNRFKITPRELRKASRE"
     gene            complement(14495..15046)
                     /gene="ybcL"
                     /locus_tag="LSX49_002323"
     CDS             complement(14495..15046)
                     /gene="ybcL"
                     /locus_tag="LSX49_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Raf kinase inhibitor-like protein YbcL"
                     /protein_id="HBL7168724.1"
                     /translation="MKKLIVSSVLAFITFSAQAAAFQVTSNEIKTGEQLTTSHVFSGF
                     GCEGGNTSPSLTWSGAPEGTKSFAVTVYDPDAPTGSGWWHWTVANIPATVTYLPADAG
                     RRDGTKLPTGAVQGRNDFGYAGFGGACPPKGDKPHHYQFKVWALKTDKIPVDSNSSGA
                     LVGYMLNANKIATAEITPVYEIK"
     gene            complement(15215..15547)
                     /gene="emrE"
                     /locus_tag="LSX49_002324"
     CDS             complement(15215..15547)
                     /gene="emrE"
                     /locus_tag="LSX49_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family multidrug efflux protein EmrE"
                     /protein_id="HBL7168725.1"
                     /translation="MNPYIYLGGAILAEVIGTTLMKFSEGFTRLWPSVGTIICYCASF
                     WLLAQTLAYIPTGIAYAIWSGVGIVLISLLSWGFFGQRLDLPAIIGMMLICAGVLVIN
                     LLSRSAPH"
     gene            complement(15891..16205)
                     /gene="fliE"
                     /locus_tag="LSX49_002325"
     CDS             complement(15891..16205)
                     /gene="fliE"
                     /locus_tag="LSX49_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBL7168726.1"
                     /translation="MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDR
                     ISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            16420..18078
                     /gene="fliF"
                     /locus_tag="LSX49_002326"
     CDS             16420..18078
                     /gene="fliF"
                     /locus_tag="LSX49_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBL7168727.1"
                     /translation="MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAK
                     APDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGL
                     PKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPS
                     LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLT
                     QSNTSGRDLNDAQLKYASDVEGRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTE
                     EQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNN
                     RQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGK
                     PLPLSNEQMKQIEALTREAMGFSEKRGDSLNVVNSPFNSSDESGGALPFWQQQVFIDQ
                     LLAAGRWLLVLLVAWLLWRKAVRPQLTRRAEAVKTVQQQALAREEMEDAVEVRLSKDE
                     QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE"
     gene            18071..19066
                     /gene="fliG"
                     /locus_tag="LSX49_002327"
     CDS             18071..19066
                     /gene="fliG"
                     /locus_tag="LSX49_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBL7168728.1"
                     /translation="MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANV
                     TQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRD
                     TASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            19059..19745
                     /gene="fliH"
                     /locus_tag="LSX49_002328"
     CDS             19059..19745
                     /gene="fliH"
                     /locus_tag="LSX49_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707825.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBL7168729.1"
                     /translation="MSDNLPWKTWTPDDLAPPPAEFVPMVESEETIIEEAEPSLEQQL
                     AQLQMQAHEQGYQAGIAEGRQQGHEQGYQEGLAQGLEQGLAEAKAQQAPIHARMQQLV
                     SEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGK
                     PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQE
                     LCRLAAPGVV"
     gene            19745..21118
                     /gene="fliI"
                     /locus_tag="LSX49_002329"
     CDS             19745..21118
                     /gene="fliI"
                     /locus_tag="LSX49_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HBL7168730.1"
                     /translation="MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCVIERQNGSKTHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAE
                     GLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
                     TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFK
                     QLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLE
                     RIFPTVS"
     gene            21137..21580
                     /gene="fliJ"
                     /locus_tag="LSX49_002330"
     CDS             21137..21580
                     /gene="fliJ"
                     /locus_tag="LSX49_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HBL7168731.1"
                     /translation="MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWR
                     EKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE"
     gene            21577..22704
                     /gene="fliK"
                     /locus_tag="LSX49_002331"
     CDS             21577..22704
                     /gene="fliK"
                     /locus_tag="LSX49_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HBL7168732.1"
                     /translation="MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTD
                     KAAPQLLVATDKPTTKGEPLISDIVSDAQQADLLIPVDETLPVINDEQSTSTPLTTAQ
                     TMTLAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPAEKP
                     TLFTKLTSAQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPH
                     QTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK
                     VDDNQAQIQMISPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ
                     QQQSQRTANHEPLTGEDDDTLPVPVSLQGRVTGNSGVDIFA"
     gene            22809..23273
                     /gene="fliL"
                     /locus_tag="LSX49_002332"
     CDS             22809..23273
                     /gene="fliL"
                     /locus_tag="LSX49_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HBL7168733.1"
                     /translation="MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADD
                     KAQQRVVPSPVFYALDTFTVNLGDADRVLYIGITLRLKDEATRSRLSEYLPEVRSRLL
                     LLFSRQDAAVLATEEGKKNLIAEIKTTLSTPLVAGQPKQDVTDVLYTAFILR"
     gene            23278..24282
                     /gene="fliM"
                     /locus_tag="LSX49_002333"
     CDS             23278..24282
                     /gene="fliM"
                     /locus_tag="LSX49_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HBL7168734.1"
                     /translation="MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQR
                     RVVRERLQALEIINERFARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRNEDQNWRDNLVRQVQHSQLELVANFADISLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK
                     "
     gene            24279..24692
                     /gene="fliN"
                     /locus_tag="LSX49_002334"
     CDS             24279..24692
                     /gene="fliN"
                     /locus_tag="LSX49_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HBL7168735.1"
                     /translation="MSDMNNPADDNNGAMDDMWAEALSEQKSTSGKSAADAMFQQFGG
                     GDVSGTLQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            24695..25060
                     /gene="fliO"
                     /locus_tag="LSX49_002335"
     CDS             24695..25060
                     /gene="fliO"
                     /locus_tag="LSX49_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HBL7168736.1"
                     /translation="MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGF
                     APKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEI
                     PQTDFQSVMKNLLKRGGRS"
     gene            25060..25797
                     /gene="fliP"
                     /locus_tag="LSX49_002336"
     CDS             25060..25797
                     /gene="fliP"
                     /locus_tag="LSX49_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310714.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBL7168737.1"
                     /translation="MRRLFSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQT
                     LVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            25807..26076
                     /gene="fliQ"
                     /locus_tag="LSX49_002337"
     CDS             25807..26076
                     /gene="fliQ"
                     /locus_tag="LSX49_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBL7168738.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQI
                     NEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG"
     gene            26085..26870
                     /gene="fliR"
                     /locus_tag="LSX49_002338"
     CDS             26085..26870
                     /gene="fliR"
                     /locus_tag="LSX49_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HBL7168739.1"
                     /translation="MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKL
                     GLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEII
                     GLQMGLSFATFVDPGSHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
                     SEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADIISELPLI"
     gene            27160..27783
                     /gene="rcsA"
                     /locus_tag="LSX49_002339"
     CDS             27160..27783
                     /gene="rcsA"
                     /locus_tag="LSX49_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HBL7168740.1"
                     /translation="MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACD
                     SQRPSVVFINEDCFIHDASNSQRIKHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLL
                     ISSKSIKPESLDDILGDILKKDTTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
                     QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR"
     gene            complement(27827..28015)
                     /gene="dsrB"
                     /locus_tag="LSX49_002340"
     CDS             complement(27827..28015)
                     /gene="dsrB"
                     /locus_tag="LSX49_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HBL7168741.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNEAGHQDGIFVEKAE"
     gene            28178..28405
                     /gene="yodD"
                     /locus_tag="LSX49_002341"
     CDS             28178..28405
                     /gene="yodD"
                     /locus_tag="LSX49_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HBL7168742.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            28701..29516
                     /locus_tag="LSX49_002342"
     CDS             28701..29516
                     /locus_tag="LSX49_002342"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HBL7168743.1"
                     /translation="MFSIQQPLLVFSDLDSTLLDSHSYDWQPAAPWLSRLHEANIPVI
                     LCSSKTSAEMLYLQKMLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEICQ
                     VLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQ
                     FIARLNELGLQFMQGARFWHVLDASAGKDQAANWITATYQQLSGRRPTTLGLGDGPND
                     APLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR"
     gene            complement(29513..31207)
                     /gene="yedQ"
                     /locus_tag="LSX49_002343"
     CDS             complement(29513..31207)
                     /gene="yedQ"
                     /locus_tag="LSX49_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
                     /protein_id="HBL7168744.1"
                     /translation="MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWRE
                     VVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAV
                     TEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
                     LRLAHNSSSMVEQAVYVSRAGFYVSTLPTLFTRNVPTRYYGYVTQPWFIGHSQRENRH
                     RAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLKNAIDKNLD
                     GEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWERL
                     DHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQS
                     SLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQ
                     AGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGANLTQAAEVAERIRLKLNEKE
                     MLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFASDNA"
     gene            complement(31378..31560)
                     /locus_tag="LSX49_002344"
     CDS             complement(31378..31560)
                     /locus_tag="LSX49_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HBL7168745.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRSAEEV"
     gene            complement(31639..32556)
                     /locus_tag="LSX49_002345"
     CDS             complement(31639..32556)
                     /locus_tag="LSX49_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HBL7168746.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKMRGQAH"
     gene            32729..33649
                     /gene="yedA"
                     /locus_tag="LSX49_002346"
     CDS             32729..33649
                     /gene="yedA"
                     /locus_tag="LSX49_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HBL7168747.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLLAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVI
                     VFAVVLVTLGKYLFPAKPVVAPVIQDASSE"
     gene            complement(33638..34108)
                     /gene="vsr"
                     /locus_tag="LSX49_002347"
     CDS             complement(33638..34108)
                     /gene="vsr"
                     /locus_tag="LSX49_002347"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VSPR family DNA mismatch endonuclease"
                     /protein_id="HBL7168748.1"
                     /translation="MVDVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDAALTERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(34089..35507)
                     /gene="dcm"
                     /locus_tag="LSX49_002348"
     CDS             complement(34089..35507)
                     /gene="dcm"
                     /locus_tag="LSX49_002348"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-cytosine methyltransferase"
                     /protein_id="HBL7168749.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENH
                     WSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPEHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFNEDIRDITLSHQEGVSDEAAAEH
                     IRQHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRP
                     AMFVLENVKNLKSHDKGKTFRIIMQTLDELGYDVADAADNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMATGEKDFDDP
                     LNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            complement(35574..36269)
                     /locus_tag="LSX49_002349"
     CDS             complement(35574..36269)
                     /locus_tag="LSX49_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBL7168750.1"
                     /translation="MELQHWQAQFDNWLKNHHQHQDAAHDLCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVTLAKNHPQRQRSSILAAEETRRLLREEFAQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGLALFDGEDPFAQ
                     HRPLDDKRYALDHFQTKLLKLPQTMQTARGKQLAQHNAQFLVEFMAKLGAELAGENEG
                     IDHKVIDAFSPAG"
     gene            complement(36309..36674)
                     /locus_tag="LSX49_002350"
     CDS             complement(36309..36674)
                     /locus_tag="LSX49_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL7168751.1"
                     /translation="MEKCDFYHIIVLSLNFPGYLKMEYGSTKMEERLSRSPGGKLALW
                     AFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGAL
                     LGGIAWYTRPRPARCRRYE"
BASE COUNT         9071 a         9556 c         9211 g         8946 t
ORIGIN      
        1 caggcaatga attacttttg caagccatcg cattctctta tgttattaat gagttatgct
       61 gatttgttaa gcagttttat cacgtttgaa atggcgtccc gccccgactg gtgaatcgtc
      121 ggggctgatt ttttcttatt attgcagcag aaacttctcc aggaactggc gggtgcgagg
      181 ctgctgagga tcagcaaata acgcttttgc taccccctgc tcgactatcc gcccctggtc
      241 cataaaaatc gcccggtccg caacatcccg ggcaaagctc atttcgtgcg tcacaatcac
      301 catcgtgcgc ttttcctgcg ccagctgacg aatggtgttc aggacttcgc ccaccagctc
      361 tggatccagc gccgacgttg gctcgtcaaa caaaatcact tcaggacgca ttgccagagc
      421 acgcgcaatc gcaacgcgct gctgttgacc gccagacaaa cgacgtggat aactggtttc
      481 tttaccggcc agcccaactt tcgccagcag ctcgcgagcg cgcgccgtgg cctcttcttt
      541 cggttcgcct ttgacgatca ccggcccttc aataatgttt tccagcaccg tacgatgcgg
      601 aaacagatta aagttctgga agacaaaccc gacgtgctga cgcaactggc gaatcagcga
      661 tttttgctga cttaatgaac gtgcagtatc aatagtgata tcgccaacgg tgatggttcc
      721 cgcttccggt tgttccagca gatttatgct gcgtagcaac gtggttttgc cggaaccact
      781 cggaccgata attgccacta cttcgcctgg cttcacctca aggtcgatac catgcagcac
      841 cgtctgaccg tggaattttt tcaccaggtt cttaacttca atggcactca tttgggttct
      901 ctctcctggc gattaagttg attctcaaaa tggttctgca acgtcgataa cacagtcgcc
      961 atgatccagt agatgagcga agccgccagg tacatggtga acacctccag cgtgcgcgag
     1021 gtaatcaact gcgcctgacg gaacagctcc ggcacctgga ttgtcgcggc cagcgacgta
     1081 tcttttacca ggctgataaa gctgttcgac agcggcggca acgccacccg cgccgcctgt
     1141 ggcaaaatcg cgcgacgcat ggtctgccat ggcgtcatac caatactggc tgcagcttcc
     1201 cactgacctt tatcaataga agaaatggcg gcgcgcagcg tttcagcagc ataggcggca
     1261 gtgttcagcg acagaccaat cattgctgac ggaatgggat ctaattcgat accaaactgt
     1321 ggcagtccgt aatagatcat aaacagttgt gcgatgagcg gcgtaccacg aaaaatagag
     1381 atataaaaac gcgccagcca gcgcacgggc cagattggcg acaggcgcat cagcgcgaga
     1441 ataaacccga gcagtaagcc aaaaaacatg cctccgatac tgagttgcag cgtataccca
     1501 gcccctttca gcaggaacgg caaggaatca ataaccagtt gtatactttc ttgcatgagc
     1561 gttcccggag ctaaacgtgg ggatgatagg cgaacagcgc aggcgcaccg ccggtatgaa
     1621 taaacaaaat cggcccttca tctttgaagc gtttctgact gataccgtca atcagccccg
     1681 ccatcgcttt tccggtatac acaggatcaa gcagaatgcc ttccagcctc gccagcaatt
     1741 tcactgcttc catgccttcg tcgttcggca cgccgtagcc aggtgcaaaa tagtcatccc
     1801 agagtaaaat ttccgctgat gcggtcagct ccagttcttt cgcaatcgcc tgttggaggt
     1861 taaccacttt cggcaattga tcggcaactg aacgcgacac agtcacgcca atcagttcgc
     1921 tttcaggcat cagctgttcc agcccaacag ccagtccggc gtgagttccg gcactgcccg
     1981 atgcgaccac caccgacgaa atattaaccg ccacttcaca ctgttgcgcg atttccagcg
     2041 cactctccac ataacccagc gcgcccaaag cattagaacc gccaaccgga atgacatacg
     2101 ggcgaaagcc ttgtgcttcg actcgcgtcg ccagctcttc cagttgggca ttgggatcgg
     2161 tcagtgcgtc gcacatttca atctgggtat tgaacagatc cagcaacaaa cgattgccgt
     2221 tggttaaata gttttccgcg gttgtaccaa taggattttc cagcagcgcc acgcagtgca
     2281 gaccgagttt cgcagcgact gcggcagtct ggcgcacatg gttagactgg atcgccccgg
     2341 cagtaatcag cgtatcggca ccttcacgca gagcatctgc cgcgagaaat tccagcttac
     2401 gtaatttatt gccgcccatt gccatgggag tgacgtcatc ccgtttgatg aaaatttccc
     2461 gtccaagata atcagaaaag cgcggcagat attcgagcgg cgttggcgcg ccaataaact
     2521 ccagccgtgg aaaacgggtt aaattatgca gtggcataac agcctccgat gtgtgttgtt
     2581 gtgattttct tattatgcac gctgaaaacg cgtaaataaa aaaggcgcta gtgaaagcgc
     2641 ccttttttgt cattatgctg attatttggt cacatcagca ccaaaccatt tttcggaaag
     2701 ggcttgcaaa gtgccatctt tttgcatttc cgcaattgca tcattcaccg ctttcagcag
     2761 gtcttcattt cctttacgca gcgccacgcc agactcctga cgagagaatg cttcaccggt
     2821 tactgccagc gtatcgttgg ttttcttcac cagatccagc gccgccagac gatcaacgag
     2881 gatcgcatcg atacggccta cgcgcagatc ctgatatttg gtcgggtcat catcataggt
     2941 acgcacatcg acgccctgaa cattctgacg cagccactct tcatagttgg tgcccagacc
     3001 gacacccact tttttgcctt tcagatcatc agccgtttta atggtgcctt cgttgccttt
     3061 tttcaccagc gcctgaatac cagaaatggt gtacggggta gagaaatcgt attttttctt
     3121 gcgctcgtca gaaatggtga cctggttaat caccacatca atgcgtttag agtccagcga
     3181 cgccagcata ccgtcccatt tggtcggttt tagtgacgcc tcaacgccaa gatgttttgc
     3241 cagttgttgg gcaaattcca cttcaaaacc ggttaatttg ccgtcatccc cctgaaaact
     3301 gaacggcgga taagttcctt ccagccctac cagcagcgtg ccgcgctctt tgactttatt
     3361 aagcagacct tcatctgcaa aacttttaac gctcataccc gcaaccagcg ccacggccat
     3421 cacacccatc aatgcctgac gtcccagatg tgctaatttc atattcaccc cgaatgttgt
     3481 tatgtctgtt tgcagtgtag agccattgtt tgtaaacaca aaaacaactc cgctacatct
     3541 tattcttatt taatatatat cagaagcagg caggctggag gatttctgca caagtccggt
     3601 acacgtttga cgctgatagt gttgatactt ccgtaacgcg atgcggtaat tgttggtgct
     3661 ggtggagggc agccacgggg cgaggatttc atcgaggaaa ccgtcctgca gctgatcgag
     3721 ggaaatattt tgctcgtgta gatgattccc caaacggcgc agacgaacga catattcacg
     3781 caccgtacca gggctcattt cagtttgctc aaaaagaaat tgcttaaagc cgataatatc
     3841 gaaaaaatca ctctgcgttt tgcaatgtaa atcaccgcaa aatcggcaca atgccgccca
     3901 tgattgttgt tccacttgcc agccattttc atcaagcagc gtgtccaggc gggaaatctc
     3961 gattttattc actattttgc cgtcgcgaac gagggtaatg cgatcgagta atttacggca
     4021 atgcgcgcaa tgggtctggc tgtgtttaaa gtctttaaga tagcggctta atggccgtct
     4081 tttcaggtgc tgcaccatca ttaagaactc ctggtagtca aaattaaagt gcggcattta
     4141 ctgacgttat aacttaccca gtttagtgcg taaccgttta atagcctggc tgtgtaactg
     4201 actgacccgc gattccccga cctccagcac cgcaccaatc tctttgagat tcagctcttc
     4261 ctgataatag agggttaata ccagtttttc gcgctccggc aacgtttcga tggcttccat
     4321 cacccgctgg cgcagattat tgtccagcag ttgttgtagc gggttttctc gctgatgatc
     4381 atcagtaacc agttcgatgc tatcgccgtg ctcttcgcgc cactcatcgt aggagaagag
     4441 ctggctgtta ttggtgtcga gcaacatttg gcgataatcg gcaatatcga tccctaaacg
     4501 ttccgctacc tcagtttccg tggcgttgcg gccaagttcc tgctccagtt gccctattgc
     4561 ctgtgccact tcacgcgcgt tgcgtcgcac gctgcgcggc acccagtcac ggctgcgaag
     4621 ttcatccagc atagcgccac ggatacgctg cactgcgtaa gttgtaaatg ccgttccttg
     4681 tagggcgtca tagcgttcga cggcattaag taacccaatg ccgcccgcct gtagcagatc
     4741 gtcaagttcc acgctcgcgg gcagtcgaac ctgcaggcgc aatgcttcgt gacgcaccag
     4801 cgggacataa cgctgccaca gcgagtgttt atccattaca ccttcagcgg tatagagtga
     4861 attcacgata aacagccctg cgttatatga gttatcggca tgattatccg tttctgcagg
     4921 gtttttaatc ggacgattag tgggtgaaat gaggggttat ttgggggtta ccggtaaatt
     4981 gcgggcagaa aaaaccccgc cgttggcggg gtcaggcagg ttaaggccat tagccttgta
     5041 acagagacag aacttgctgc ggtacctggt tggctttaga cagcacggag ttgcccgcct
     5101 gctggataat ctgcgctttc gacatgttgg acacttcggt cgcatagtcg gcgtcctgaa
     5161 tacgggactg cgcttcagac aggttggtgg tggtgttgtt caggttggtg accgcagaat
     5221 ccagacggtt ttgaacggca ccgagggagg agcggaattt gtcgacttta gcgattgcgg
     5281 catccagtgc ttttaacgga tcggctgtag cggctcccgc cacttccgct gcaccaacag
     5341 ttaccgccgc cgccgtaccg gtaatgacta cagtggcttc catgtattta ccggttgcag
     5401 aatcaacgac cgcatattta gtactgttag acgcggtgtc agtgtaagac agtaaattga
     5461 cttgtttacc cccagcatcc ttgacatccg cagcagcaat tgctgtacca tcagcagccg
     5521 tcagtttcgc cgcgctgaaa tccgccatgc cggacacggt aaatcctttc agattcaaag
     5581 tggtactgtc gatttgttgc aagccaatgc tgatcgtctg gttatcattg gcaccaatct
     5641 gaatcttcat cgaatcgttt ttcgacagca cgttcacacc gttgaactgg gtctgaccag
     5701 atacacggtc aatttcatca agacgggatt tgatttcgtc ctgaatagaa gacaggtcgg
     5761 aatcagagtt cgtgccggta gaggcctgaa cggtcagttc acgaatacgc tgcaagttgt
     5821 tgttaatctc tgacagcgcg ccttcagccg tctgcgccag agaaataccg tcgttggcgt
     5881 tacgtgcggc ctgagtcaga cctttgatgt tagaagtaaa gcggttagca atcgcctggc
     5941 ccgcggcgtc atctttagcg ctgttaatac gcagaccaga agagaggcgc tcgatagaag
     6001 tcgacagcgc agactggttt ttgttgatgt tgttctgagt gatcagcgag aggctgttgg
     6061 tattaatgac ttgtgccata attcattttc ctgttttcaa gtctacggtt taagtattgg
     6121 gcttccaccc ttcggcttcg tcgccgtcaa ccctgttatc gtctggtcac tcacaacctt
     6181 tagaattttt ttctagcggt cgaaatactc cccttcctcg ttgctgttcg tgccattaag
     6241 gcaaaaaata aatcgtaaac tttaccccgc ttacgccgat aaccccggta ttcgttctat
     6301 acacgtcgca tgattaagga aactatatgg ctagtatttc aacgcttggg gttgggtcgg
     6361 ggctggactt aagcagcatc cttgacagtc tggaggcggc agaaaaatct accctgacgc
     6421 cgatatcaaa acagcaaagc tcttacaccg cgaaactgag cgcctacggg acgctgaaaa
     6481 gtgcactaga gagtttccag acagccaaca cagcactgaa taaagccgat ttatttaccg
     6541 ccacctcaac caccagcagt tcatcggctt tcagcgccac caccacgggc agcgcgattg
     6601 ctgggaaata caccattagc gttagccaac tggcgcaggc acagacgctg acaacaaaaa
     6661 atagtcaaaa agacagtaaa gccgccatcg ccaccagcga tagcgtactg accatccaac
     6721 aaggcggcgg taaagatccg gtcacgattg atatcagcgc gggtaactcg tcactttccg
     6781 gcattcgcga tgccattaac aacgccaaag ctggtgtcag cgccagtatc atcaatgtgg
     6841 gaaacggcga atatcgtctg tccatcaccg ctaacgatac gggcagcaat aacgctatga
     6901 aacttagcgt cagcggcgac agcgccctgg aaagttttat gggttacaac ggaacgccgg
     6961 gtgatagcag caatggcatg attgaaagcg tcaccgcgca aaacgccaaa ctgacagtca
     7021 ataacgttga gattgaaaac agcagtaaca ctatcagcga ctcactggaa gatatcaccc
     7081 tcaacctgaa tgacgtcacc accggtaatc agacactgac catcagtaaa gacacatcca
     7141 aagctgaaaa tgcggttaaa gcgtgggtgg atgcctataa cacattgcag gatacattca
     7201 gcagcttaac caaatacacc gctgtcgatg ccggagctga aagtcaggac tccagtaatg
     7261 gcgcattact cggtgactcc acactgcgta ccatccagac tcagcttaaa accttgctcg
     7321 ccaatactca cagcagttca aactataaaa cgctggcaca gattggcatt accagcgatg
     7381 ccagtaccgg caagctggaa atcgcgaccg acaaactgca aacggcgcta aaaaatgatg
     7441 ccgctggtat cggtgaaatg tttataggtg acggcaaaag tactggggta accaccggca
     7501 ttagtagcaa cctgaccagt tggctctctt ccaccgggat aatccaggca gcaaaagatg
     7561 gcgtcagcaa aacgctgaat aatttgaccg accagtacaa cgcagccagt gaacgtatcg
     7621 ataccttaat gacgcgctat aaagcccagt tcacccaatt agatgtgtta atgaactcgc
     7681 tgaactccac tagtagctat ctgacacagc agttcgacac ctcaaatagc aactcgaaat
     7741 aatcttcagg agagactatg tacgcggcaa aaggcaccca ggcctatgca caaattggcg
     7801 tcgaaagcgc cgtaatgagc gccagccaac agcagttggt caccatgcta tttgatggag
     7861 tgttgagcgc actggttaga gcgcgcctgt ttatgcagga caacaatcag caaggcaaag
     7921 gcgtctcttt gtcaaaagcg atcaacatca ttgagaacgg actgcgggtg agtcttgatg
     7981 aagagagcaa agacgaacta acccaaaact tgattgctct ttatagctat atggtcaggc
     8041 gtttgctgca agccaattta cgcaacgatg tctccgcagt cgaagaagtg gaagcattaa
     8101 tgcgcaatat tgccgatgcc tggaaagagt ctttactctc cccttctttg attcaggacc
     8161 cagtctgatg aacaatgcac cgcatttgta tttcgcctgg caacaactcg tcgaaaaaag
     8221 ccagctcatg ttacgcctgg caacggaaga acaatgggac gaactcatcg ccagcgaaat
     8281 ggcgtatgtg aatgcggtgc aggagatcgc acacctgact gaagaggttg ccccgtccac
     8341 tacgatgcag gagcagctcc gcccgatgct gcgcctgatt ctcgacaacg aaagcaagat
     8401 aaagcagtta ttacagattc ggatggatga actggcgaaa ctggtcggtc agtcatcggt
     8461 gcaaaaatcg gtgttaagtg cctatggcga tcagggcggc tttgtgctgg ctccgcagga
     8521 taacctcttt tgaatcttaa tgagccgatg gctcgcgaat aatccgatta cggctacgct
     8581 tctaatattc cccttgaatg gagtcgaaga atgcgtaatc ccacgctgtt acaatgtttt
     8641 cactggtatt acccggaagg cggtaagctc tggcctgaac tggccgagcg cgcagacggt
     8701 tttaatgata ttggtatcaa tatggtctgg ttgccgcccg cctataaagg cgcatcgggc
     8761 ggctattcgg tcggctacga ctcctatgat ttatttgatc taggtgagtt tgatcagaaa
     8821 ggcagcatcc ctactaaata tggtgataaa gcacaactgc tggccgccat tgacgccctg
     8881 aaacgtaatg acattgcggt gctgctggac gtggtagtca accacaaaat gggcgcggat
     8941 gaaaaagaag ctattcgcgt gcagcgtgta aatgctgatg accgtacgca aattgacgaa
     9001 gaaatcattg agtgtgaagg ctggacgcgt tacaccttcc ccgctcgtgc cgggcaatac
     9061 tcgcagttta tctgggattt caaatgtttt agcggtatcg accatatcga aaaccctgat
     9121 gaagatggca tttttaaaat tgttaacgac tataccggag aaggctggaa cgatcaggtt
     9181 gatgatgaac tcggtaattt cgattatctg atgggggaga atatcgattt tcgcaatcat
     9241 gccgtgacgg aagagattaa atactgggcg cgctgggtga tggaacaaac gcaatgcgac
     9301 ggctttcgtc ttgatgcggt caaacatatt ccggcatggt tttataaaga gtggatcgaa
     9361 cacgtacagg aagttgcgcc aaagccgttg tttattgtgg ctgaatactg gtcgcatgaa
     9421 gtcgataaac tgcaaacgta tattgatcag gtggaaggca aaaccatgct gtttgatgcg
     9481 ccgctgcaga tgaaattcca tgaagcatcg cgcatgggtc gcgactacga catgacgcag
     9541 atcttcactg ggacgctggt ggaagccgat ccttttcacg ccgtaaccct cgttgccaac
     9601 cacgacaccc aaccgttgca agccctcgaa gcccccgtcg aaccgtggtt taaaccgctg
     9661 gcgtatgcct taattttgtt gcgggaaaat ggcgttcctt cggtgttcta tccggacctc
     9721 tacggtgcac attacgaaga tgtcggtggt gacgggcaaa cctatccgat agatatgcca
     9781 ataatcgaac agcttgatga gttaattctc gcccgtcagc gtttcgccca cggtgtacag
     9841 acgttatttt tcgaccatcc gaactgcatt gcctttagcc gcagtggcac cgacgaatat
     9901 cccggctgcg tggtggtcat gtcgaacgga gatgatggcg aaaaaaccat tcatctggga
     9961 gagaattacg gcaataaaac ctggcgcgat tttctgggga accggcaaga gagcgtagtg
    10021 acagacgaaa acggcgaagc gaccttcttt tgcaacggcg gcagcgtcag cgtgtgggtt
    10081 atcgaagagg tgatttaaat ccatccccgg cggcaagccg gggagatttc attacggcag
    10141 tggcgtcggt aacggcgctt tatccagcgc ggcggcacac tctgccgtcg ggcgatccac
    10201 acgctccatc gtcataccat cgtactcaat ggtgttaccg tcacgctcaa cctcgtacag
    10261 ctcacgtttt acggtaacgt tagtgagatc atcagacatc aatgtcaact tacccggcac
    10321 ggcaatcacc cgctgccact gacggcaatc cagggtatcg ccctctttag tgacaatgag
    10381 gctgcctatc gcttccggac tgaccaacgc acgttgcggc cctttggtct gccagtaacc
    10441 cgtcagccag tccggcgcgg gggttttcac gacattgtta tagttttcga cttcggcaca
    10501 gcccgccagc aacatgagcg cacctgcaat tgcgagtttt ttcatcattc gtcctgcatg
    10561 agaagaaaag aggattgtgg cattaaagcc ctgatgtcgc cagcctttcc aggttcagag
    10621 agaaatttga tctaaccatt atttttgtga attattaccc cgaaaataaa tttgcatggt
    10681 gtatgattcg cgactcttgt ttcaaacctt ctgagttcag aggctacatt catgtcatgg
    10741 cagcaattca aacacgcctg gttgattaaa ttctgggcgc ccatccccgc ggtcatcgcg
    10801 gcgggtattc tctccactta ctattttggc atcactggca ccttttgggc agtcacgggt
    10861 gaatttaccc gttggggcgg tcagctcctg cagttgttcg gcgtccatgc tgaagagtgg
    10921 ggttatttta aaattatcca tctggaagga tcgccattaa cccgcatcga cggaatgatg
    10981 atcctcggta tgtttggcgg ctgttttgcc gcagcgctgt gggccaacaa tgtcaaactg
    11041 cgcatgccgc gcagccgtat ccgcattatg caggccatca ttggcggtat tatcgccggt
    11101 tttggcgcac gtctggcaat gggctgtaac ctggcggcgt tctttaccgg aattccacag
    11161 ttctcgctgc acgcctggtt ctttgccatc gccactgcca ttggttcatg gtttggcgcg
    11221 cgctttaccc ttctgcccat cttccgtatt cccgtgaaaa tgcagaaagt ttctgctgcc
    11281 tcaccgttga cgcaaaaacc ggatcaggcg cggcgtcgtt ttcgtctcgg gatgctggtc
    11341 tttttcggca tgctgggctg ggcgctgctg acggcgatga accagcccaa actggggctg
    11401 gcaatgctgt ttggcgtcgg ctttggttta ctgattgaac gtgcgcaaat ctgctttact
    11461 tcggcgttcc gcgatatgtg gatcaccgga cgtacccata tggcgaaagc aatcattatc
    11521 ggtatggcgg taagtgccat cgggatcttc agttacgtac agttaggcgt tgaacccaaa
    11581 atcatgtggg cgggaccaaa cgcggtaatt ggtggtttac tgtttggttt tggcatcgtg
    11641 ctggcaggcg gctgcgaaac cggctggatg taccgcgcgg tagaaggcca ggtgcactac
    11701 tggtgggtcg gtctgggcaa cgtgatcggc tcaacgattc tggcgtacta ctgggatgat
    11761 ttcgctccgg cgctggccac cgactgggac aaaatcaacc tgctgaaaac ctttggcccg
    11821 atgggcggcc tgctggtgac atatttgctg ttgtttgctg ctctaatgtt gattattggc
    11881 tgggaaaaac gcttcttccg ccgtgcggca ccgcagactg ctaaggagat cgcatgaaaa
    11941 atatcgttcc tgattaccgt cttgatatgg tgggtgaacc ctgcccttat ccggcagtcg
    12001 caacccttga ggcgatgccg cagttaaaaa aaggggagat cctggaagtg gtgagcgact
    12061 gtccgcagtc gatcaataat attccactgg atgcgcgtaa tcacggctat acggtgctgg
    12121 atattcagca agacgggccg accattcgtt atttaattca gaagtaatcc ctcattcccg
    12181 ctgtggccca cagcgggaac atcgttacct ctctatcaca tagattttac ccgccctctc
    12241 tcctattctt ttcagtgtgc tctcaggagg tttctatgtg tggacgcttt gcccaatccc
    12301 aaacgcgtga agattacctc gcgtttctcg cggaagatat tgaacgcgat attccctacg
    12361 atcccgaacc tattggcaga tacaacgtcg cgccgggaac caaagtcctt ctgctcagtg
    12421 aacgtgatga acaccttcat ctggatccgg ttttctgggg atatgctccc ggatggtggg
    12481 ataaaccgcc gctgattaac gcccgcgtag aaactgccgc aaccagtcac atgtttaaac
    12541 cgctctggca acatggtcgg gcaatctgtt ttgccgatgg ctggtttgag tggaaaaaag
    12601 aaggcgacaa aaagcagcct tattttatct atcgtgctga tggacaagct gtttttatag
    12661 ccgcgatagg tagcacaccg tttgagcgtg gtgacgaagc cggaagaagt ttttgtaagc
    12721 ccgctcaggg tctttcagtg actgttgcaa tggctgtgag ggcgaatctt taagccattg
    12781 cgtttcagtg gcatttttcc actcaaccaa ccaggaagcc attttcccgt aagggatgta
    12841 tttattaccg gcctcatgat tctcattctg aagcgccaga gcacgattga aaacgaaacg
    12901 acatgcgcct gcgaagcgcc tcattccacg ctcctgttga ccacctggtc ttaaccggaa
    12961 tttgaatgcc tgtagtcgtt tcatgggcca aatcatactt tggcctatga aaaaagaaac
    13021 cgatatccga cgcggaaggc attgtgtttt cctgaagcat gttcacctgg tcttcgttac
    13081 taaataccga cgtcagattt ttgaccatga cgcgacagaa aaactacgca cttacttttc
    13141 aaatgtatgt gctgattttg aagctgaacg ggttgaaatg gatggcggac cagatcacgt
    13201 ccatttgtta attaactatc ctcccaaact ggcgatatcc agtctggtaa acagcctcaa
    13261 aggcgtatcg agtaggttac tgcgacgaga tcgaccagat attgcagtca ggtattacga
    13321 caaaggcgtt ttgtggagtc ctggctattt tgtcagtagc tgcatcttaa cgtatcaact
    13381 agatttaata acaacgatat ccgtacctaa ccggatatct aatgtcataa gcatcccttt
    13441 aattatcccc tcaacctctt gtaactttcc cactcttgag ctccacatag tccaaacgcc
    13501 ggatgcaaaa aaatcacacg tgcatttctg aaattgtgat ggaggaagat agtatcaatt
    13561 atatgtgctt agaaacgtcc ccgattagcg cagaagtcac cggattgttc agactccaat
    13621 aggttgagta tgccgtattt attttccaaa ataaaaatcg atgctgttgc tccttcataa
    13681 aatactttta ctctctggac gcttttctta gctctcttgg tgttatctta aaacgattat
    13741 ggaacctttc agtaaaacga gaaggacact tgtaaccatt ttccctggca atctcgctga
    13801 tgggttttac tgtcgtttgt atagcagaca acgcattatt taacctcacg tcgtccaata
    13861 tactttgaaa acttactccc tcgcttgcca gacggcgatg caatgtggaa acagaaatgt
    13921 agagatatct cgctaccttg tttgctgtcc attttgttcc aggttcggat agcattaggt
    13981 tataacaacg acttattaat gattgtttac tatctgataa aagtaaacaa ttaacatgat
    14041 gtgctcctaa tgaaagtaga acgcccattg ctaagtgttc ctgaatttgc gttgagaagc
    14101 ctcgggaaat agatgttttt agttgctccc aacaatatat taactcgggg ttctgaggta
    14161 agcagaaacc tgtcgtgtta cgaatttgat cagttatcgc ataaaatttt tgaaactttt
    14221 caattagatc aatgggataa caaagcattt ctgcaagata aagacctgct tctggataat
    14281 tcgcaatata aaattcatat ccacagggaa ataatattat ctgattatta tcaacagtta
    14341 gactatgcgt ctcccaattg ataacttttt ttccctgacg gatacgacat aaagctggca
    14401 taagaggctt aaccctgtga atctcatgat gtttatgcat ccgtatttct tcaatcttta
    14461 ggttagtctt atcttttgcc agcatactct taccctactt tatctcataa actggtgtta
    14521 tctcagcggt tgcaatttta ttggcattaa gcatataacc aactaacgct ccgctggaat
    14581 tagaatccac aggaatttta tcagttttta gagcccatac tttaaactgg taatgatggg
    14641 gtttatctcc tttgggagga catgctccac caaatcctgc ataaccaaaa tcatttcggc
    14701 cttgaacagc accagtcgga agttttgtac catcacgtct tcctgcatca gcgggcaaat
    14761 atgttacagt tgctggaata ttagcaacag tccagtgcca ccatccactg cctgtaggag
    14821 catctggatc atacacagtt acggcaaagc ttttggtgcc ttcaggagca ccagaccagg
    14881 ttaatgaggg cgatgtatta ccaccttcac acccaaatcc agaaaataca tgagacgttg
    14941 taagttgctc tcctgttttt atttcattac tagtgacctg aaatgctgcg gcctgcgcag
    15001 aaaatgttat gaatgccaat acacttgaaa cgataagttt tttcataaaa acctcattgt
    15061 tgtgacctat cgttatttta tttgatgtgc cttgatctca ttatgcataa aggcgcaatg
    15121 atcgcgcaaa tgcaatcata attataaagg tgccccgaac attagccata atatgcacaa
    15181 atcagattcc tgttatctca aggataatta ttttttaatg cggtgcactt cgtgacaaca
    15241 agttaatgac taacacaccg gcacaaatca acatcatgcc tatgatagct ggcaggtcca
    15301 gtcgttgacc aaaaaatccc caggaaagca aactaatcag aacgataccg actcctgacc
    15361 agatagcata agcaatccct gtaggtatat aagccagcgt ctgagctaat aaccagaatg
    15421 atgcacaata gcaaataatt gtgccaacag agggccataa ccgtgtaaac ccctctgaaa
    15481 acttcattaa ggttgtacca atgacctctg caagtattgc gccaccaaga taaatataag
    15541 ggttcatagc atattctttc ctgttcatac tggagagaat tgtactacag tttgaacaca
    15601 actcactgtt ttcatcctgg tgtatgtgta tccagggggc tctggcgtgg caagagataa
    15661 aggcaggaac aataatgatc agaaggaacc ccaggctaac gaaagagttc actcttcctg
    15721 ggagcaaagc gaagacaaaa catgttatcg cgtttacgga tcgtggatgg cagaaaacaa
    15781 ccaggatcag gtatccattt taaaccagaa attgagtgag tttgcccatc catgccccac
    15841 gctgtgggat cggatataat taaacaagca tagtcaacag gttacacaac ctacacctgc
    15901 atggacatca cttcctgata cgccgccacc agcttattac gcacctgaat ccccatttgc
    15961 atagaaactg aggctttttg catatcggtc atcacatcgt ttagcgccac gccgggttca
    16021 ccgagggtga atttttctgc ctgcgtgcgg gcggctgttt gtgtatcgct tatgcgatcg
    16081 agcgcggcgt gcagctgccc ggcaaaacta atggtcggtt gcggcagtga ttcctgcgca
    16141 cgcgcactca tcgccgtagc ctgtaactgg ctgataaccc cttcaatccc ctgtatcgct
    16201 gacattttcg tctcccggat aatttctgat agcaaagcct accagtaagt caataagaca
    16261 aaggcgctaa atagcaacaa aaaaacgggt ttattggcgg atagaaaaaa acgaaagcac
    16321 aaataatggg agcgtcaatt tttcgagttt gctgacccgg gagtgagtct tgttccactt
    16381 tgccaataac gccgtccata atcagccacg aggtgcgcga tgaatgcgac tgcagcccag
    16441 acaaaatctc ttgagtggct taatcgcctg cgtgcgaatc cgaaaattcc attgattgtt
    16501 gccggttccg cagcagtggc ggtcatggtc gcactgatcc tgtgggcgaa agcccccgac
    16561 taccgcacat tattcagcaa tctttccgat caggatggtg gcgcaattgt cagccaactg
    16621 acgcaaatga atattcctta ccgcttcagc gaagccagcg gcgctattga ggttccggca
    16681 gataaagttc acgaactgcg cctgcgcctg gcgcaacaag gtttgcccaa aggcggcgcg
    16741 gtcggtttcg aactgctcga tcaggaaaag tttggtatca gccagttcag cgaacaggtg
    16801 aattatcagc gggcgctgga aggcgagctt tctcgtacca tcgaaactat cggcccggta
    16861 aaaggggcgc gcgtacatct ggcaatgccg aaaccgtctt tattcgtccg tgaacaaaaa
    16921 tccccttctg catcggtgac ggtaaatctg ttacccggcc gcgcactcga tgaagggcaa
    16981 attagcgcta ttgtacatct ggtttccagc gcggttgctg gtctgccgcc aggaaacgtc
    17041 acgctggtgg atcagggcgg gcatctgtta acccagtcca ataccagcgg gcgcgatctt
    17101 aatgacgctc agttgaaata tgccagcgat gtcgaaggcc gtattcagcg gcgtattgaa
    17161 gcgatcctgt cgcctattgt tggtaacggt aatattcacg cccaggtcac ggcgcaactg
    17221 gacttcgcca gtaaagaaca aacggaagaa cagtatcgcc ctaacggtga tgaatctcat
    17281 gcggcgcttc gttcacgcca gcttaatgag agcgagcaaa gcggttccgg ttatccgggc
    17341 ggcgtaccgg gggcgttgtc gaatcaaccg gcacctgcga ataacgcacc aatcagcacg
    17401 cctccggcaa atcaaaataa ccgccagcag caggcgagca ccaccagcaa tagtgggccg
    17461 cgtagcacac agcggaatga aaccagtaac tacgaagtcg atcgcaccat tcgtcatacc
    17521 aaaatgaacg tgggcgatgt gcaacgtctg tcagtcgcgg tagtggtgaa ttacaaaacc
    17581 ttgccagacg gtaaaccatt gcctctcagc aacgaacaga tgaagcaaat tgaagctctg
    17641 acccgcgagg cgatgggctt ttctgaaaaa cgcggtgatt cgctcaatgt tgttaactcg
    17701 ccgttcaata gcagtgacga aagcggcgga gcactgccgt tctggcaaca gcaagtgttt
    17761 atcgatcagt tgctggctgc cggtcgctgg ttgctggtac tgctggtggc gtggttgctg
    17821 tggcggaaag cggtacgccc gcagctaaca cgtcgcgccg aggcggtgaa gactgtgcag
    17881 caacaagcgc tggcccgcga ggaaatggaa gatgcggtgg aagtccgtct gagcaaagac
    17941 gaacaactcc aacaacggcg cgctaaccaa cgactggggg cagaagtcat gagccagcgt
    18001 atccgtgaaa tgtctgataa cgatccgcgc gtggtggcgc tggtcattcg ccagtggata
    18061 aataacgatc atgagtaacc tgacaggcac cgataaaagc gtcatcctgc tgatgaccat
    18121 tggcgaagac cgggcggcag aggtgttcaa gcacctctcc cagcgcgaag tgcaaaccct
    18181 tagcgctgca atggcgaacg tcacgcagat ctccaacaag cagctaaccg atgtgctggc
    18241 ggagtttgag caagaagctg aacagtttgc cgcactgaat atcaacgcca acgattatct
    18301 gcgttcggta ttggtcaaag ctctgggtga agaacgtgcc gccagcctgc tggaagatat
    18361 tctcgaaacc cgcgataccg ccagcggtat tgaaacgctc aactttatgg agccgcagag
    18421 cgccgccgat ctgattcgcg atgagcatcc gcaaattatc gccaccattc tggtgcatct
    18481 gaagcgcgcc caggccgccg atattctggc gttgttcgat gaacgtctgc gccacgacgt
    18541 gatgttgcgt atcgccacct ttggcggcgt gcagccagcc gcgctggcgg aactgaccga
    18601 agtactgaat ggcttgctcg acggtcagaa tctcaagcgc agcaaaatgg gcggcgtgag
    18661 aacggcagcc gaaattatca acctgatgaa aacgcagcag gaagaagccg ttattaccgc
    18721 cgtgcgtgaa ttcgacggcg agctggcgca gaaaatcatc gacgagatgt tcctgttcga
    18781 gaatctggtg gatgtcgatg atcgcagcat tcagcgtctg ttgcaggaag tggattccga
    18841 atcgctgctg atcgcgctga aaggggccga gcagccactg cgcgagaaat tcttgcgcaa
    18901 tatgtcgcag cgtgccgccg atattctgcg cgacgatctc gccaaccgtg gtccggtgcg
    18961 tctgtcgcag gtggaaaacg aacagaaagc gattctgctg attgtgcgcc gtcttgccga
    19021 aactggcgag atggtgattg gcagcggcga ggatacctat gtctgataat ctgccgtgga
    19081 aaacctggac gccggacgat ctcgcgccac caccggcaga gtttgtgcca atggtcgagt
    19141 cggaagaaac cattattgaa gaggccgaac ccagccttga gcagcaactg gcgcaactgc
    19201 aaatgcaggc ccacgagcag ggttatcagg cagggattgc cgaaggtcgc cagcaaggtc
    19261 atgaacaggg ctatcaggaa ggactggccc aggggctgga acaaggtctg gcagaggcga
    19321 aggctcaaca agcgccaatt catgcccgga tgcagcaact ggtcagcgaa tttcaaacta
    19381 cccttgatgc gcttgatagt gtgatagctt cgcgcctgat gcagatggcg ctggaggcag
    19441 cacgtcaggt cataggtcag acgccaacgg tggataactc ggcactgatc aaacagatcc
    19501 aacagttgtt gcagcaagaa ccgttattca gcggtaaacc acagctgcgc gtacacccgg
    19561 atgatctgca acgtgttgat gatatgctcg gcgcaacttt aagtttgcat ggctggcgct
    19621 tgcggggcga tcccaccctc catcctggcg gttgcaaagt ctccgccgat gaaggcgatc
    19681 tcgacgccag tgtcgccact cgctggcaag aactctgccg tctggcagca ccaggagtgg
    19741 tgtaatgacc acgcgcctga ctcgctggct aaccacgcta gataactttg aagccaaaat
    19801 ggcgcagttg cctgcggtac gtcgctacgg gcgattaacc cgcgctaccg ggctggtgct
    19861 ggaagccacc ggattacaat tgccgctcgg cgcaacctgt gtcattgagc gccagaacgg
    19921 cagcaaaacg cacgaagtag aaagcgaagt cgtcggcttt aacggtcaac ggctgttttt
    19981 aatgccgctg gaggaagtgg aaggtgtcct gcccggcgcg cgtgtatatg ccaaaaacat
    20041 ttcggcagaa gggctgcaaa gcggcaagca gttgccgctc ggtccggcgt tattaggtcg
    20101 tgttctggac ggcagcggta aaccgctcga tggcctcccc tcccccgata cgacggaaac
    20161 cggtgcgctg attaccccgc catttaaccc attgcaacgt acaccgattg aacatgtgct
    20221 ggacaccggc gtgcgcccaa tcaatgccct gcttaccgtc gggcgcgggc agcgtatggg
    20281 gctgtttgcc gggtccggcg ttggtaaaag tgtgctgttg gggatgatgg cacgttacac
    20341 ccgcgccgat gtcattgtcg tgggtttgat tggtgaacgt gggcgcgaag taaaagattt
    20401 tattgagaat atcctcggtg ccgaaggacg tgcacgctca gtggtgattg ccgctccggc
    20461 ggatgtttct ccgctcctgc gaatgcaagg tgccgcctat gccacgcgca ttgccgaaga
    20521 ttttcgcgat cgtggtcagc atgtgttgct gattatggac tccctcaccc gctacgcgat
    20581 ggcccagcgt gaaattgcgc tggcgattgg cgaaccacct gctactaaag gttatccacc
    20641 gtcggtgttt gccaaattac cggcactggt cgagcgtgcc ggaaatggca ttagcggcgg
    20701 cggctcgatt accgcgtttt ataccgtgct caccgagggc gatgaccagc aggaccccat
    20761 tgccgactcc gcgcgggcca tcctcgacgg tcacattgtg ctgtctcgcc gactggcgga
    20821 agccgggcac tatccggcta tcgatattga agcgtcgatc agccgcgcaa tgacggcgtt
    20881 gatcagtgag caacattacg cacgagtgcg caccttcaaa cagctgttgt cgagttttca
    20941 gcgtaaccga gatctggtta gcgtcggcgc gtatgccaaa ggcagcgatc cgatgctcga
    21001 caaagccatc gccctgtggc cgcagctgga gggctatttg caacaaggca tttttgaacg
    21061 cgcggactgg gaagcgtctc tccaggggct ggagcgtatt ttcccgacag tgtcataacc
    21121 caggagataa cggcagatgg cagaacatgg cgcgctggcg accctgaaag atctggcaga
    21181 aaaagaggta gaggatgccg cgcgcctgct gggtgaaatg cgtcgcggat gtcagcaggc
    21241 ggaagaacag ctcaaaatgc tgatcgatta tcagaatgaa tatcgcaata acctcaatag
    21301 cgatatgagt gccgggatga ccagcaaccg ctggatcaac tatcagcagt ttatccagac
    21361 gctggaaaaa gccattactc agcatcgcca gcaacttaat cagtggacgc agaaagttga
    21421 cattgccctg aacagctggc gagaaaagaa acaacgtttg caggcctggc agacactgca
    21481 ggaacggcaa tccacggcgg cactgcttgc agaaaaccgc ctcgatcaga aaaagatgga
    21541 tgagttcgcc cagcgcgccg ccatgaggaa acctgaatga ttcgcttagc gcccttaatt
    21601 accgccgacg ttgacaccac cacattgcct ggcggcaaag ccagcgatgc tgcacaagat
    21661 tttctcgcgt tgttgagcga agcattagca ggcgagacaa ctaccgacaa agcggccccc
    21721 cagttgctgg tggcaacaga taagcccacg acaaaaggcg agccgctgat cagcgatatt
    21781 gtttccgacg cgcaacaagc ggatttactg atccccgtgg atgaaacact gcctgtcatc
    21841 aacgacgaac aatccacatc aacaccgtta accaccgctc agacgatgac gttggctgcg
    21901 gtggctgaca aaaatacgac aaaagacgaa aaagcggatg atcttaatga agacgtcacc
    21961 gcaagcctga gcgccctttt tgcgatgttg ccgggttttg acaatacgcc caaagtgact
    22021 gatgcaccgt caaccgtgtt accggcagag aaaccaacgc ttttcacaaa actgacttct
    22081 gcgcaactca caacagcaca gcctgatgac gcccccggca caccagctca gccattaaca
    22141 ccgctggtag cagaagccca gagtaaagcg gaagtcatca gcacaccttc gccggtgact
    22201 gctgccgcca gcccgctaat cactccacac cagacacagc cactgcccac cgtcgccgcg
    22261 cctgttttga gtgcaccgct gggttctcac gaatggcaac aatcattaag ccagcatatt
    22321 tcgctgttca cccgccaggg gcaacaaagt gcagagttgc gtctgcaccc acaggattta
    22381 ggtgaagtgc aaatttccct caaagtggat gataaccagg cgcagatcca gatgatttca
    22441 ccgcatcagc acgtacgcgc agccctggaa gcagcgctgc cggtactgcg tacgcagctg
    22501 gccgaaagtg gcattcagtt agggcaaagc aacattagtg gcgaaagctt tagtggtcag
    22561 cagcaggccg cttcccagca acagcaaagc caacgcacag caaaccatga acctctgacg
    22621 ggggaagacg acgatacgct tccggttccc gtctctttac aagggcgtgt aacaggcaac
    22681 agcggcgttg atattttcgc ctaacgtcag aggtagcacc gtaatccgcg tcttttcccc
    22741 gctttgttgc gctcaagacg caggataatt agccgataag cagtagcgac acaggaagac
    22801 cgcaacacat gactgattac gcgataagca agaaaagcaa gcgatcgctt tggatcccga
    22861 ttctggtatt cattaccctc gcggcctgtg ccagcgcagg ttacagctac tggcattcgc
    22921 atcaggttgc cgctgacgac aaagcgcagc aacgcgtcgt gccctccccg gtcttctatg
    22981 cgctggatac ctttacggtc aatttgggcg atgcggatcg cgtgctttat atcggcataa
    23041 ccctgcgact gaaagatgaa gcaacccgct cgcggctgag tgagtatttg ccggaagtcc
    23101 gtagtcgctt gctgttactg ttttcacgtc aggatgctgc cgtactggcg acagaagaag
    23161 gcaagaaaaa cctgattgcc gagattaaaa ccacactttc caccccgctt gttgccgggc
    23221 aaccgaaaca ggatgtcacc gacgtgctgt ataccgcttt tattctgcga taacgacatg
    23281 ggcgatagta ttctttctca agctgaaatt gatgcgctgt tgaatggtga cagcgaagtc
    23341 aaagacgaac cgacagccag tgttagcggc gaaagtgaca ttcgtccgta cgatccgaat
    23401 acccaacgac gggttgtgcg cgaacgtttg caggcgctgg aaatcattaa tgagcgcttt
    23461 gcccgccatt ttcgtatggg gctgttcaac ctgctgcgcc gtagcccgga cattaccgtc
    23521 ggggccatcc gcattcagcc gtaccatgaa tttgcccgca acttgccggt gccgaccaac
    23581 ctgaacctta tccaccttaa accgctgcgc ggcacagggc tggtggtgtt ctcgccgagc
    23641 ctggtgttta tcgccgtgga taacctgttt ggcggcgatg gacgcttccc gaccaaagtg
    23701 gaaggtcgcg agtttactca taccgaacag cgcgtcatca accgcatgtt aaagctggcg
    23761 cttgaaggct atagcgacgc ctggaaagcg attaatccgc tggaagttga gtacgtgcgt
    23821 tcggaaatgc aggtgaaatt taccaatatc accacctcgc cgaacgacat tgtggttaac
    23881 acgccgttcc atgtggagat tggcaacctg accggcgaat ttaatatctg cctgccattc
    23941 agcatgatcg agccgctacg ggaattgttg gttaacccgc cgctggaaaa ctcgcgtaat
    24001 gaagatcaga actggcgcga taacctggtg cgccaggtgc agcattcaca gctggaactg
    24061 gtggccaact ttgccgatat ctcgctacgc ctgtcgcaga ttttaaaact gaaacccggc
    24121 gacgtcctgc cgatagaaaa acccgatcgc atcatcgccc atgttgacgg cgtcccggtt
    24181 ctgaccagtc agtacggcac tctcaacggt cagtatgcgt tacggataga acatttgatt
    24241 aacccgattt taaattctct gaacgaggaa cagcccaaat gagtgacatg aataatccgg
    24301 ccgatgacaa caacggcgca atggacgata tgtgggctga agcgttgagc gagcaaaaat
    24361 caaccagcgg aaaaagcgct gccgacgcaa tgttccagca atttggcggc ggagatgtca
    24421 gcggaacgtt gcaggatatc gacctgatta tggatattcc ggtcaagctg accgtcgagc
    24481 tgggccgtac gcggatgacc atcaaagagc tgttgcgtct gacgcaagga tcagtcgtgg
    24541 cgctggacgg tctggcgggc gaaccgctgg atattctgat caacggttat ttaatcgccc
    24601 agggcgaagt ggtggttgtt gccgataaat atggcgtgcg gatcaccgat atcattaccc
    24661 cgtccgagcg gatgcgccgc ctgagccgtt agtgatgaat aaccatgcta ctgtgcaatc
    24721 ttccgcgccg gtttctgctg cgccactgct gcaggtgagc ggcgcactca tcgccattat
    24781 tgccctgatc ctcgctgccg cctggctggt aaaacggctg ggatttgccc ctaaacgcac
    24841 tggcgttaac ggtctgaaaa ttagcgccag tgcttcgctg ggcgcgcgtg aacgggtcgt
    24901 ggtggtcgat gtggaagatg cacggctggt gctcggcgtt accgcagggc aaatcaatct
    24961 gctacataaa cttccccctt cagcaccaac ggaggagata ccgcagaccg attttcagtc
    25021 ggtcatgaaa aatttgctta agcgtggcgg gagatcctga tgcgtcgttt gttttctgtc
    25081 gcaccggtcc ttctctggct gattacgccc ctcgccttcg cgcaactgcc gggtatcacc
    25141 agccagccgc tacctggcgg tggacaaagc tggtcgctcc cggtgcagac gctggtgttc
    25201 atcacctcgt tgacgttcat tccagcgatt ttactgatga tgaccagttt cacccgcatc
    25261 attattgttt ttggtttatt gcgtaacgcg ctgggaacgc cctccgcgcc acctaaccag
    25321 gtattgctgg gactggcact gtttttgacc ttttttatta tgtcgccagt gatcgacaaa
    25381 atttatgtcg atgcgtacca gccattcagc gaagagaaaa tctcaatgca ggaggcgctg
    25441 gaaaaagggg cgcagccgct gcgtgagttt atgctgcgtc agacccgcga ggcggattta
    25501 gggttgtttg ccagactggc gaataccggc ccgttgcagg ggcctgaagc tgtgccgatg
    25561 cgcattttgc tcccggccta cgtgaccagc gagttgaaaa ccgcatttca gataggcttc
    25621 acgattttca tccctttttt gattatcgac ctggtgattg ccagcgtgtt gatggcattg
    25681 gggatgatga tggttccccc agccaccatt gctctgccct ttaaactgat gctgtttgta
    25741 ctggtggatg gctggcaatt gctggtcggt tcgctggcgc agagctttta cagctagaga
    25801 ggcaaaatga cacctgaatc ggtcatgatg atggggactg aagcgatgaa agtcgcgctg
    25861 gcactggctg ccccactgtt gctggtggcg ctggtcacgg gtcttatcat cagtattttg
    25921 caggccgcca cgcagatcaa cgaaatgacg ctgtcgttta ttccaaaaat catcgccgta
    25981 tttatcgcca ttattattgc cggaccgtgg atgctcaatc tgttgctgga ttacgtccgc
    26041 accttgttca ctaacctgcc gtatatcatc gggtaggccg tacaatgatg caggtaacaa
    26101 gcgatcaatg gctttcctgg ttaagcctgt acttctggcc gttactgcgc gtgctggcgc
    26161 tcatttctac cgcgccaatt ctgagcgaac gcagcgtgcc gaaacgggta aaactgggtc
    26221 tggcaatgat gatcacgttc gccattgccc catcattacc tgccaacgat gttcctgttt
    26281 tttcgttctt tgctctgtgg ctggccgtgc agcagatcct gatcggcatt gcgcttggtt
    26341 ttaccatgca atttgccttt gccgctgtgc gaaccgctgg cgaaattatc ggtctgcaaa
    26401 tggggctgtc atttgcgaca tttgtcgatc ctggcagcca tctcaatatg cccgttttag
    26461 cgcgcatcat ggatatgctg gcattactgc tgttcctgac atttaacggt catttatggt
    26521 tgatttcact gctggtcgat acctttcaca ccctgccgat tggtagcgaa ccgttgaaca
    26581 gcaatgcgtt tctggcactc accaaagcag ggagtttgat tttccttaac gggctgatgc
    26641 tggcgttacc gctcattact ctgttgctga ccctgaatct ggcattaggt ttactgaatc
    26701 gtatggcccc gcaattatcc atttttgtta ttggatttcc attaactctg actgtcggca
    26761 tctctttaat ggcggcatta atgccgttaa ttgcgccttt ttgcgaacat ttattcagtg
    26821 aaatttttaa tttgctggct gatattatta gtgaattacc attaatataa ttccgtaacg
    26881 tttatcatgc taccctaagg attatccgaa aaataatatc tgcgaacatc ttccaggata
    26941 ctcctgtagc gaaatatttg ttttaagctc actcacatat cgcaacattt actttacttt
    27001 aagacaattc caggcaaatt atacaacact ttacgggata gtaagtccgc ctgaaaaatt
    27061 gcgagagtgg cgcattaggt gacccatgtt gttccgttta gtcatgatga aatattcagg
    27121 taaggggaat tatcgttacg cattgagtga gggtatgcca tgtcaacgat tattatggat
    27181 ttatgtagtt acacccgact aggtttaacc gggtatctgt tgagtagagg ggttaaaaaa
    27241 agagaaatca acgacattga aaccgttgat gaccttgcca tagcttgtga ttcacagcgc
    27301 ccttcagtgg tgtttattaa tgaggactgt ttcatccacg atgcttctaa cagtcagcgc
    27361 atcaagcaca tcattaatca acatcccaat acgttattta tcgtttttat ggcaattgcc
    27421 aatgttcatt ttgatgaata tctattggtc agaaaaaatt tattgatcag ctctaaatcg
    27481 attaaaccgg aatctctcga cgatatcctt ggcgatattc tgaaaaaaga tacaacgata
    27541 acctcgtttt taaatatgcc gactttatca ttgagccgaa ccgaatcgag tatgttgcga
    27601 atgtggatgg caggtcaggg aaccattcaa atctccgacc aaatgaatat caaagccaag
    27661 accgtttcat cgcataaagg taatattaaa cgtaagatca aaacgcataa taaacaggtt
    27721 atctaccatg tcgtccgact gacggataat gtgactaatg gtatttttgt caacatgcgc
    27781 taacacattc tgactggtgg tttcccacca gtcaggctga ataagattac tctgctttct
    27841 caacaaagat accgtcctga tgccctgctt cattaaagaa ccagatgccg agcgggtagt
    27901 cttccagcga aaccaggtac attgtgcctt cactaaactc ctcaactgcc agtaccacgc
    27961 caggacgacg cggaccgcca tccgttttga ctgttacccg atcattcacc ttcatcgttt
    28021 tcctcctgtg gctttgtgcc agtgtagaac aatttcgttt ttctggcagc gccaggcgcg
    28081 cgcgagtgct gattttctcg acggtctata cttaagagat gccaggcgga cttaacgact
    28141 ggcggcaaca acagagtaac ggttgcgagg aaagatgatg aaaaccgcaa aagagtacag
    28201 cgataccgca aaacgtgagg tcagcgtcga tgtcgatgcc ctgctggcgg cgatcaatga
    28261 aattagcgaa agcgaagttc atcgcagcca gaacgattct gaacacgtta gcgtcgatgg
    28321 acgtgaatat catacatggc gtgaattggc ggatgccttc gaactggata ttcatgactt
    28381 cagcgtctct gaagtgaatc gttgaatgca caataaaaaa atcccgaccc tgagggggtc
    28441 gggatgaaac ttgcttaagc aagaagcact taaaaaattc gttacaccag gaaatctgat
    28501 gtgttcatca ccttatctgc aatttttttc gctgacaaga aaatattcgc gctatgaatg
    28561 attaacgcta cttatgaata gaaatgtgac gcgcgtcacc ccttggtggc tctggtgtca
    28621 acgggatcgc tcccgaaaaa atcatctttg attatttgtg ctgttttgag aatcatcctg
    28681 gtaaggggag tactgcgccc atgttttcaa ttcaacaacc actactggtt tttagcgatc
    28741 ttgatagcac cctgctggac agtcatagtt atgactggca accggcagcc ccctggctca
    28801 gccgtttaca cgaagccaat attcccgtca ttctctgtag cagtaaaact tcagcggaaa
    28861 tgctgtactt gcaaaaaatg ttggggctac aaggcttacc gctgattgca gagaatggcg
    28921 cagtgatcca gcttgctgaa caatggcagg atatagacgg ttttccacgc atcatctcag
    28981 gtattagcca tggcgaaatc tgccaggttt taaatacgct acgcgagaaa gaacatttta
    29041 aattcacgac ttttgatgat gtcgacgatg caaccattgc cgaatggacg ggattaagcc
    29101 gtagccaggc ggcgctgacg cagctgcatg aggcgtcggt aacgctaatc tggcgcgaca
    29161 gtgacgagcg tatggcacaa tttatcgctc gtctgaacga actgggcttg cagtttatgc
    29221 agggtgcgcg cttctggcac gtactggatg cctctgccgg aaaagatcag gctgccaact
    29281 ggattaccgc gacctatcaa caattgtcag gcagacgccc aaccacactt ggcctgggcg
    29341 atgggccaaa cgatgcgcct ttactggagg taatggatta cgcggtgatt gtgaaagggc
    29401 taaaccgtga aggggtccat ctgcatgatg aggatccggc ccgcgtctgg cgaacgcagc
    29461 gtgaaggacc ggaaggctgg cgtgaagggc tggaccattt tttctccgcc cgttaagcgt
    29521 tatcgctcgc gaatacccga ttacgcccgg cctgttttgc gaggtaaagc cgacggtcgg
    29581 ccaatgactg gagttgttca aaatcataat caccggtttc ctcgctgcta cttaccccca
    29641 gcgaggcact gatgcgtatc gttgtactct tggcgatcag catctctttt tcatttaact
    29701 tcaggcgaat acgttctgcg acctccgcag cctgcgtcag attcgcgcct ggcagaatca
    29761 cacaaaactc ctcaccaccg acccgcccgg caacgtcctg cgcacgcaag gaactgctaa
    29821 ttaatccggc agcatgagaa agaacacggt cgcccgcctg atgaccaaag cggtcattaa
    29881 tcgctttaaa atggtcaaga tcgacctgaa tgacagaaaa aggatgttgg tgcgtctgac
    29941 acaatttagc gagcggacgg gctttttcga acaatgcgcc acggttatat aaacgcgtta
    30001 aggtgtcgtg ccacgcctgc cactgcaacg agctttgcag aacatacatg ttgctgacca
    30061 tccggcgaat cacataccag gagatgagta acatggtggt aaagagcgcc cacagcaggg
    30121 ttaatgcaat gctgatactg ccgaaatcgc cgcgcacgcc ttcgcttagc gtatggacgc
    30181 gcaccagcac accgtcgaaa tggtccagac gttcccagct aacatagcga ctgtccatac
    30241 gaatgccgcc ccgcgtgtca tgttccattg cctgcgccag caaggccagt tcacgaggat
    30301 caaaaatatt ccctgttgga tggtcaggat ttgaagaggt caaaaatctc agcttactgt
    30361 catagagctg atactcacca tcgaggtttt tatcgatggc gttttttaaa aattgctgca
    30421 tagtacgcac gggaatactc atccccagca cgccatacca gtagttatta ctgtctaccg
    30481 gaacactgac ggtaacctgc ggttcagtat tgctggcgtg ttccggttgc gaagtgaacc
    30541 agcgtaccgc gcggtgacga ttttctcgtt gtgaatggcc gataaaccag ggttgggtga
    30601 catagccgta ataacgcgtt ggtacattgc gcgtaaacaa ggtcggcagc gtcgaaacgt
    30661 aaaatccagc acgcgagaca tacaccgcct gttcaaccat cgacgaggag ttgtgcgcca
    30721 gtcgcagcaa gtaaccaact tccagtgcag cggtaatttc attgtcgagg ctttcatttt
    30781 cgcgagacag gagattcccc tcgctgacta atgcatccga tacgccattg actggcaggg
    30841 tgcgccgtcg gttgagttcg atttgccagg cgtgctcgtc gcgatgctgt tcgaactcgg
    30901 ttacggcatt acgcagagag gtgaaatcca gtggcgccac gagagcttcg cgcatgccat
    30961 tacgcaaaaa gatcagtttg tcgacgttat actgcaaatg cttatcgagc gcgttggcta
    31021 cgttttccag atgattacgc tggctggaga tataggcatc ttccagcacc accacttcac
    31081 gccaggtgag caaggtggaa aaaagcaata ccacgataaa gcagagatta acgacatgac
    31141 cgggccccag gcggcgtgcg agttttttca accagctctg gttttccatt tttgtctcgt
    31201 gctgcaccct gacgactccc aacctgcttt tttatgattc tggcataacc cggcgatagc
    31261 gtaccgcaaa acagcgataa ttttataatg gtggcatgat aagacgcgac tatcattcat
    31321 tgcaggcatt gggacaccag gccggatgtg atccggcctg gtgttaatga taccctttca
    31381 aacttcttcc gcagaacgac tcccctcccc cggaacaagc tcggtttcat gaaaagcttc
    31441 ccgcttgacc ccgtacccgt cataccaacg acactcaacc ataccgctgg agtatccagt
    31501 gacaatcatc cgcgggccgc cctctttaac cgtaacttcc tcactaacca taaagctcat
    31561 actcgcctcc ttttttcgag tgaaacttgt tcaccttagt tgaagatggc gaattttgca
    31621 taatagcctg tgcgagtatt aatgtgcctg accgcgcatt ttcgctacgg ctttcactcc
    31681 cagcaccacg atgccgccga tgataaatcc aagaatcaga tttaaaacag tcggtaatat
    31741 catcgccacc actgcacttt gctgcccggc gaaatgttca atggcgtgat gcaacggcgc
    31801 aataccatgt accacaatcc cgccgccgac gaggaacatc gccagcgtgc cgacaatcga
    31861 taacgctttc atcaaccagg gcgcaatgat caataaccct ttacctaatg cctgcatcag
    31921 cgcgctggat ttttccgcca gccaataccc caggtcatca atcttaacga taacccctac
    31981 cagaccgtag acgcccacgg tcactaccag cgcgatgcct gaaagcacca gcacctgatt
    32041 aagcaacggc gcttctgcca caatccccag cgtgatggcg acgatttccg cagacaatat
    32101 aaaatcggta cgaatcgccc cttttatttt gtccttttca aacttcagcg gatcctgcgc
    32161 cgccagcttc tccagacgct gctgactctg cgccggatct tctttatgtt tacgcgcctc
    32221 cagcatatgc agcactttct ctaccccttc aaagcagaga aacgcgccgc caatcatcaa
    32281 cagtggcgta atcgcccacg ggataaacgc actgatgatc agcgccagcg gcaccagaat
    32341 cactttattg atcagcgaac ctttcgccac gccccagacc acgggaagtt cccggttggc
    32401 ccgcacgcct gaaacttgtt gcgcattgag cgataagtca tcccctaata caccggcggt
    32461 tttcttcgcc gccagtttgc ccatcacgga gatatcgtcc agcagtgtgg cgatatcatc
    32521 gagcaacgtc agtaaactac tcccggccaa aagcattccc tctcattttt attgttgaag
    32581 ggtgtaagta tgaagcaaaa acggcagctc tgatacttgc ttcacaggtc aacatttatt
    32641 taacaatcaa gtgcaattat atctctcgcc agcagaatga ttttcacgtt tactatgaac
    32701 caccttttta tttcagccgt gagggattat gcgtttccgc cagttgttac cgctttttgg
    32761 cgcgctgttt gcgttgtata tcatttgggg ctcaacctat tttgtcattc ggattggcgt
    32821 ggaaagctgg cctccgttaa tgatggcggg cgttcgattc ctggcagccg gtattttatt
    32881 gctggcattt ttgctactgc gcggacacaa acttcccccg ctacgtccgc tgctcaatgc
    32941 cgcgctgatt ggcctgttat tgctggctgt cggtaatggc atggtgacgg ttgccgaaca
    33001 tcaaaatgtt ccttccggca tcgccgccgt agtggttgca accgtgcccc tttttaccct
    33061 gtgcttcagc cgcctgtttg gcattaaaac gcgcaaactg gaatgggtgg gtatcgccat
    33121 tgggcttgcc ggaatcatca tgctcaatag cggtggaaac ttaagcggca atccatgggg
    33181 cgcgattctg attttaatcg gctcgattag ctgggcgttt ggctcggttt atggctcgcg
    33241 cattacctta cctgtaggga tgatggcggg tgcgattgag atgctggcgg ctggcgtggt
    33301 gttaatgatt gcgtcgatga ttgcgggtga aaaactgacg gcgctccctt ccctttcagg
    33361 cttccttgcg gtcggctatc tggcgctgtt tggttcgatt atcgccatta acgcttatat
    33421 gtatttaatc cgcaacgtca gtccggctct cgccaccagc tacgcctacg ttaacccggt
    33481 ggtcgcggtc ttgctgggta cgggactggg tggcgaaacg ctgtcgaaga ttgaatggct
    33541 ggcgctcggc gtaattgtct tcgcggtggt actggtcacg ttgggaaaat atctcttccc
    33601 ggccaaaccc gttgtcgcgc cagttattca ggatgcatca agcgagtaaa tgaatcccct
    33661 gcgtgtcgat ctgcgcgctg gcaccttcgc cgcagatcca ctcttccaga cgctcggtaa
    33721 gcgccgcatc cgtaagcttc tcgcgcccac gtaacgcaca ctcccagaca atcagtacgc
    33781 gccagccgag ttcctgcaag cgactgatat cgcggcgatc gcgttcaaca tttttaccta
    33841 tcttctccag ccagaactcg gttcgagtcg caggcacttt aaacagatag cagtgatgat
    33901 gatgccagaa gcagccgtgg gtaaatatca cgcagcgata ttcatcaacg acaaaatccg
    33961 ggcgtccggg cagactggcg tcctgaacgc gaaacgcaag gccctgcccg gttaacaaac
    34021 tggcgaggcg cttctcaatc gccgtatcac gcgtggcaat cgcgcgcata tttttgctgc
    34081 gggtggcctt atcgtgaacg tcgaccatgt tgtgcctctt gctgacgcaa cgccaccgcc
    34141 tgtttgattt ttggctcaag cagttttgcc accgcggcaa agaccggcac gaccaccgag
    34201 ttaccgaact ggcgataggc ctgagtgtcc gaaaccggaa tgcggaattt cgcttctccc
    34261 ggcgcttcaa aacccattaa gcgcgcgcat tcacgaggtg ttaaccgacg tggacgatgt
    34321 tgctgattca gcggatcgtc aaagtctttc tcacccgtgg ccatatccca gccgcggtcg
    34381 attaaaattt ccgcgccatc cttgtaataa cgagcagaca gcgtacgggt gacgctttgc
    34441 ggattgttcg gataaaccat tccataaccg aagccgttac cgcgcgcctg atgttttttc
    34501 gcatatcgat agaggtactt ccacagcacc ggcgtcagga tatatttcgc ctcaaccatc
    34561 gggtccagca gctgcgccag cgtcactcgc tgtgcaggga aacattcgct gatatcacgc
    34621 agagtaaaat cggctttcag attcagatcg cgacgaaaac ccaccagcac gatgcgttca
    34681 cggtgctgcg gcaggaaatg tttaccgtcg atgattttcg gatcgtccgg cccgttatct
    34741 gctgcgtcgg caacgtcata gcccagttcg tccagcgtct gcatgatgat gcggaacgtt
    34801 tttcccttat cgtgactctt caggtttttg acattttcga gcacaaacat cgccggacga
    34861 cgcgcgtcga taatgcgcac cacatcaaag aacagcgtac cctgggtatc gcaggcaaaa
    34921 ccgtgcgccc gcccgagcga gttctttttc gatacgccag ccagcgaaaa tggctgacaa
    34981 gggaaaccgg ccagtaaaac atcgtgttca ggaatgtgtt gacgaatatg ttccgccgcc
    35041 gcctcatcac tcacgccttc ttgatgactg agggtgatgt cgcggatatc ttcattaaaa
    35101 tgatgcgtcg ccgggtcgca ataatggttg gctttataag tgcgtacagc atgtttgttc
    35161 cattcgctgg taaacacgca ctgtccgcca atcgattcaa aaccgcgacg gatgccgcca
    35221 attccggcaa atagatcgat aaagcgaaac gcataatgcg gatgatgttc cggtggtttg
    35281 ggtaacaacg tttgcagatg ggcaaactct ttctcactta aacggtgcca tgccgagtca
    35341 ttcgccagcg cacgttttaa aattgccgcg ctccagtgat tctcacccac accattaagc
    35401 tgcgccacca gcgttttaac atcataaatt tgcagcagtt tctccagcat tgcctgtgcg
    35461 gcattcccgg tgctgtatga atcggttact gatatatttt cctgcataga tttaaccggc
    35521 catctgagat ggccgacagg ttaacataat tactgccgtt tagggccacg cgctcagcca
    35581 gcgggtgaaa acgcatctat caccttgtga tcgatacctt cattctcccc cgccagttcg
    35641 gcaccgagct tcgccataaa ctcgactaaa aattgcgcgt tgtgctgtgc cagctgcttg
    35701 cctcttgcgg tttgcatggt ttgcggtaat ttcagtaact ttgtctggaa atgatccagc
    35761 gcgtagcgtt tatcatcaag cgggcgatgc tgtgcgaacg gatcttcgcc atcaaacagc
    35821 gccaagccca atgcccctga aacggcaaat acgcgcgcca ggccaatcgc ccccagggct
    35881 tccagccgat ccgcatcctg gacgatttta gcttccgttg ttaagggggc gatttgcgcg
    35941 ctgaaactgt gagcggcaat ggcatgacaa acggcctcaa ttttctccgc cggaaattgc
    36001 gcgaactctt cacggagcag gcgacgcgtc tcttctgccg ccaggattga agaacgctgc
    36061 cgttgcggat gatttttcgc cagggtcacg atatcgtgaa aataacaggc ggttaaaatc
    36121 accagcatat cgacatcgtc atctgccgcc agtttctgtg ccgtagccca gacacggcga
    36181 aaatgacaca agtcatgcgc cgcgtcctga tgttgatgat ggtttttcaa ccagttatcg
    36241 aactgtgcct gccagtgttg taactccata cgcgctccgt tgccaaagag tcgcaacctt
    36301 agcagttttt attcatagcg tctgcaacgt gcgggacgag gtcgggtgta ccatgcaatg
    36361 ccgcctaaca aggcaccaac cagggccata aacagaaatc cgaccaatgc tcctaaccac
    36421 ttccccgcgg tagatcctaa atcactttca aatcccgaca cgggggcatc ggggatccgg
    36481 ctcatcaccc agatgtatcg cgccattgcc cagacgaaat agccacacca tgtatagaaa
    36541 gcccacaaag ccaatttgcc gccagggctg cgagagagtc tctcttccat ctttgtcgaa
    36601 ccgtattcca ttttgagata acccggaaaa ttcagactta gaactattat gtgataaaag
    36661 tcacattttt ccacattgga tgagccagtc aagactcaat cattttttga acaaatagat
    36721 aaattttgcg caacggcggt gaatacagga aaaatcgatt tgaacgatgt tatttatctt
    36781 tgat
//
LOCUS       DAFGPF010000043        36715 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFGPF010000043 DAFGPF010000000
VERSION     DAFGPF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36715
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.043"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(210..911)
                     /locus_tag="LSX49_002351"
     CDS             complement(210..911)
                     /locus_tag="LSX49_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein P"
                     /protein_id="HBL7168752.1"
                     /translation="MKNIAAQMINFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVF
                     SQLLATFPASLANRDQNELNEIRRQWVLAFRENGITTMEQVSDGMRVARRQNRPFLPS
                     PGQFVAWCREEASVTAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
                     YQNMRANALTDAELRRKAADELACMTARINRGEAIPEPVKQLPVMGGRPLNRAQALAK
                     IAEIKAKFGLKGAMK"
     gene            complement(908..1927)
                     /locus_tag="LSX49_002352"
     CDS             complement(908..1927)
                     /locus_tag="LSX49_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL7168753.1"
                     /translation="MTGSEMAKAGLLEQNRLSGANRNTLIAGGIMANTAEIFNFPVPD
                     AAQKEPRVADLDDGYTRIANELLEAVMLAGLTQHQLLVFLAVMRKTYGFNKKLDWVSN
                     EQLSELTGILPHKCSAAKSVLVKRGIFIQSGRNTGINNVVSEWSTLPESGKKNKVYLK
                     EVNLPESGKKSLPKSGKGVYPNQVNTKDKLTKDNIKPFSSENSGESSDQPENDLPVVK
                     PDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLMRERDGRNHR
                     DMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQAGVTASKPKLDLTNTDWI
                     YGVDL"
     gene            complement(1924..2463)
                     /locus_tag="LSX49_002353"
     CDS             complement(1924..2463)
                     /locus_tag="LSX49_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT domain-containing protein"
                     /protein_id="HBL7168754.1"
                     /translation="MQPLTYQQTSGFSPTAVINRSQTKQVPGHEKIRDAVRAWSAVDN
                     QDVVATLIVNEYLEQGGGTIDFPDDVSRARQKLFRFLDNKFDSEKYRNNVRELTPAIL
                     AVLPLEYRGYLVEQDSFMARLAEMEKELSEAKQAVILNAPRHQKLKEISEGIVSMFRV
                     DPDLAGPLMAMVTTMLGAI"
     gene            complement(2533..2763)
                     /locus_tag="LSX49_002354"
     CDS             complement(2533..2763)
                     /locus_tag="LSX49_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7168755.1"
                     /translation="MNPAIKTAINIVGSQKKLGAACEVSQQAVYKWLHNKAKVSPEHV
                     GSIVTATGGVVKAYQIRPDLPKLFPHTEKNAA"
     gene            2868..3557
                     /locus_tag="LSX49_002355"
     CDS             2868..3557
                     /locus_tag="LSX49_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7168756.1"
                     /translation="MKTTLSERLKEARLARGLTQKALGDLVGVSQAAIQKIETGKANQ
                     TTKIVEIANALGVRAEWLSSGVGNMSDSTVQPIQSTVSHSKYFKIDVLDIEVSAGPGV
                     INREFVEVLRSVEYSFDDARHMFDGRKAENIRIINVRGDSMSGTIEPGDLLFVDITVK
                     SFDGDGIYAFLYDDTAHVKRLQMMKDKLLVISDNKSYSPWDPIEKDEMNRVFIFGKVI
                     GSMPQTYRKHG"
     gene            4153..4359
                     /locus_tag="LSX49_002356"
     CDS             4153..4359
                     /locus_tag="LSX49_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor protein"
                     /protein_id="HBL7168757.1"
                     /translation="MVHQHYGTQTVNRGAVMPGMLVKHKDGTWTASANLRGRLYLHRG
                     IERTYTRDLLVEVFLDGRGNGLNH"
     gene            4435..4731
                     /locus_tag="LSX49_002357"
     CDS             4435..4731
                     /locus_tag="LSX49_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor protein Gam"
                     /protein_id="HBL7168758.1"
                     /translation="MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLF
                     ESLCIDHLQRCGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHHVDIDSEV"
     gene            4737..5522
                     /gene="bet"
                     /locus_tag="LSX49_002358"
     CDS             4737..5522
                     /gene="bet"
                     /locus_tag="LSX49_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HBL7168759.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDD
                     DLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA"
     gene            5519..6199
                     /locus_tag="LSX49_002359"
     CDS             5519..6199
                     /locus_tag="LSX49_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBL7168760.1"
                     /translation="MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKP
                     RSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTE
                     SPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
                     SMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMASFDEMVPEFIEKMDEALAEIG
                     FVFGEQWR"
     gene            6196..6378
                     /locus_tag="LSX49_002360"
     CDS             6196..6378
                     /locus_tag="LSX49_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 domain-containing protein"
                     /protein_id="HBL7168761.1"
                     /translation="MTHPHDNIRVGAITFVYSVTKRGWVFHGLSVIRNPLKAQRLAEE
                     INNKRGAVCTKHLLLS"
     gene            6351..6542
                     /locus_tag="LSX49_002361"
     CDS             6351..6542
                     /locus_tag="LSX49_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="HBL7168762.1"
                     /translation="MHKASPVELRTSIDLAHSLAQIGVRFVPIPAETDEEFHTLATSL
                     SQKLEMMVAKAEADERDQV"
     gene            6553..6834
                     /locus_tag="LSX49_002362"
     CDS             6553..6834
                     /locus_tag="LSX49_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL7168763.1"
                     /translation="MHFSGSGLHILCAYACRHGACSVTPQQENALRSIARQANSEIKK
                     VRQQFPDKNVNDICRSVLKKHRETVTLKGFTPTHLSLAIGMLNGVFKER"
     gene            6933..7154
                     /locus_tag="LSX49_002363"
     CDS             6933..7154
                     /locus_tag="LSX49_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HBL7168764.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRLNYLAVSATHCCECGDPIDE
                     RRRLAVQGCRTCASCQQDLELIRKQRGIK"
     gene            7154..7480
                     /locus_tag="LSX49_002364"
     CDS             7154..7480
                     /locus_tag="LSX49_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL7168765.1"
                     /translation="MANLQLAVKSEYFDAMIRGEKTEEYRLCNDYWNKRIMFREYDRL
                     IITKGYPKRDDSSRRIDVPYDGYEVKTITHPHFGDKPVKVFAIKVNISTEYQSAQHKV
                     KNVQSD"
     gene            7464..7703
                     /locus_tag="LSX49_002365"
     CDS             7464..7703
                     /locus_tag="LSX49_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HBL7168766.1"
                     /translation="MFRVIDPNTWYVDHHGTPCKILRSTHNKVHYIRKGRTCIASMFR
                     FNHDFEPVNKADADRIAEEIETAEHIKKLRDMRRK"
     gene            7843..8079
                     /locus_tag="LSX49_002366"
     CDS             7843..8079
                     /locus_tag="LSX49_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBL7168767.1"
                     /translation="MSRLITLQDWAKEEFGDLAPSERVLKKYAQGKMMAPPAIKVGRY
                     WMIDRNSRFVGTLAEPQLPINANPKLQRIIADGC"
     gene            8069..9211
                     /locus_tag="LSX49_002367"
     CDS             8069..9211
                     /locus_tag="LSX49_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HBL7168768.1"
                     /translation="MAARPRSHKISIPNLYCKLDKRTGKVYWQYKHPLSGRFHSLGTD
                     ENEAKQVATEANTIIAEQRTRQILSVNERLERMKGRRSDITVTEWLDKYISIQEDRLQ
                     HNELRPNSYRQKGKPIRLFREHCGMQHLKDITALDIAEIIDAVKAEGHNRMAQVVRMV
                     LIDVFKEAQHAGHVPPGFNPAQATKQPRNRVNRQRLSLPEWQAIFDSVSRRQPYLKCG
                     MLLALVTGQRLGDICNLKFSDIWDDMLHITQEKTGSKLAIPLNLKCDALNITLREVIS
                     QCRDAVVSKYLVHYRHTTSQANRGDQVSANTLTTAFKKAREKCGIKWEQGTAPTFHEQ
                     RSLSERLYREQGLDTQKLLGHKSRKMTDRYNDDRGKDWIIVDIKTA"
     gene            complement(9325..10575)
                     /gene="icd"
                     /locus_tag="LSX49_002368"
     CDS             complement(9325..10575)
                     /gene="icd"
                     /locus_tag="LSX49_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HBL7168769.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGDAIIKNM"
     gene            10747..11400
                     /gene="rluE"
                     /locus_tag="LSX49_002369"
     CDS             10747..11400
                     /gene="rluE"
                     /locus_tag="LSX49_002369"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415653.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HBL7168770.1"
                     /translation="MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPDNQPTRVILF
                     NKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPG
                     KRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVEEPAWLWPRNPPIRER
                     KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWRDATD"
     gene            11410..11871
                     /gene="nudJ"
                     /locus_tag="LSX49_002370"
     CDS             11410..11871
                     /gene="nudJ"
                     /locus_tag="LSX49_002370"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HBL7168771.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            11925..13031
                     /gene="mnmA"
                     /locus_tag="LSX49_002371"
     CDS             11925..13031
                     /gene="mnmA"
                     /locus_tag="LSX49_002371"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBL7168772.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGTEEPWYVVDKDVENNILIVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            13067..13708
                     /gene="hflD"
                     /locus_tag="LSX49_002372"
     CDS             13067..13708
                     /gene="hflD"
                     /locus_tag="LSX49_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HBL7168773.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDGDALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            13712..15082
                     /gene="purB"
                     /locus_tag="LSX49_002373"
     CDS             13712..15082
                     /gene="purB"
                     /locus_tag="LSX49_002373"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBL7168774.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVADIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNHDHLLEELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            15251..15922
                     /gene="phoP"
                     /locus_tag="LSX49_002374"
     CDS             15251..15922
                     /gene="phoP"
                     /locus_tag="LSX49_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HBL7168775.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHL
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            15922..17382
                     /gene="phoQ"
                     /locus_tag="LSX49_002375"
     CDS             15922..17382
                     /gene="phoQ"
                     /locus_tag="LSX49_002375"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HBL7168776.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE"
     gene            17458..18579
                     /gene="roxA"
                     /locus_tag="LSX49_002376"
                     /gene_synonym="ycfD"
     CDS             17458..18579
                     /gene="roxA"
                     /locus_tag="LSX49_002376"
                     /gene_synonym="ycfD"
                     /EC_number="1.14.11.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309600.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[50S ribosomal protein L16]-arginine
                     3-hydroxylase"
                     /protein_id="HBL7168777.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGDVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(18628..19854)
                     /gene="pepT"
                     /locus_tag="LSX49_002377"
     CDS             complement(18628..19854)
                     /gene="pepT"
                     /locus_tag="LSX49_002377"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL7168778.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRK"
     gene            20104..21240
                     /gene="potA"
                     /locus_tag="LSX49_002378"
     CDS             20104..21240
                     /gene="potA"
                     /locus_tag="LSX49_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HBL7168779.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            21224..22081
                     /gene="potB"
                     /locus_tag="LSX49_002379"
     CDS             21224..22081
                     /gene="potB"
                     /locus_tag="LSX49_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HBL7168780.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFIFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKVELE"
     gene            22078..22872
                     /gene="potC"
                     /locus_tag="LSX49_002380"
     CDS             22078..22872
                     /gene="potC"
                     /locus_tag="LSX49_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HBL7168781.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            22869..23915
                     /gene="potD"
                     /locus_tag="LSX49_002381"
     CDS             22869..23915
                     /gene="potD"
                     /locus_tag="LSX49_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HBL7168782.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLSNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAAS
                     SIYEEYYQKLKAGR"
     gene            23973..24434
                     /locus_tag="LSX49_002382"
     CDS             23973..24434
                     /locus_tag="LSX49_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HBL7168783.1"
                     /translation="MSQDSRVFFRIFFGIGLVLILISVVIFYNQFTYSKDAIHTEGVI
                     VDTVWHSSHSHRTGKNGSWYPVVAFRPTPDYTLIFNSSIGSDFYEGSEGDKVNVYYSP
                     GHPEKAEINNPWVNFFKWGFIGIMGVIFISVGLLISMPSSKKTRRKRKSRP"
     gene            24431..25219
                     /locus_tag="LSX49_002383"
     CDS             24431..25219
                     /locus_tag="LSX49_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBL7168784.1"
                     /translation="MKKIIILLSLLILLPLTATSKPLIPIMKTLFTDVTGTVPDAEEI
                     AHKAELFRQQTGVAPFIVVLPDINNEASLRQNGKAMLAHAASSMSNVKGSVLLLFTTR
                     EPRLIMITNGQVESGLDDKHLGLLVENHTLAYLHADLWYQGINNALAVLQAQILKQPT
                     PPLTYYPHPGQQHENDPPGSTTTLGLFAWAVAFIVFAAFFNYTTRLYYALKFAVAMAV
                     ANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLWTSKR"
     gene            complement(25357..26178)
                     /gene="cobB"
                     /locus_tag="LSX49_002384"
     CDS             complement(25357..26178)
                     /gene="cobB"
                     /locus_tag="LSX49_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBL7168785.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQTFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL"
     gene            complement(26194..27105)
                     /gene="nagK"
                     /locus_tag="LSX49_002385"
     CDS             complement(26194..27105)
                     /gene="nagK"
                     /locus_tag="LSX49_002385"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBL7168786.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLAERLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            complement(27134..28378)
                     /gene="lolE"
                     /locus_tag="LSX49_002386"
     CDS             complement(27134..28378)
                     /gene="lolE"
                     /locus_tag="LSX49_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HBL7168787.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDNVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVNPQQEQRLSALPSFVQDDAWSNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            complement(28378..29079)
                     /gene="lolD"
                     /locus_tag="LSX49_002387"
     CDS             complement(28378..29079)
                     /gene="lolD"
                     /locus_tag="LSX49_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309522.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HBL7168788.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLEHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            complement(29072..30271)
                     /gene="lolC"
                     /locus_tag="LSX49_002388"
     CDS             complement(29072..30271)
                     /gene="lolC"
                     /locus_tag="LSX49_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HBL7168789.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            30532..31605
                     /locus_tag="LSX49_002389"
     CDS             30532..31605
                     /locus_tag="LSX49_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HBL7168790.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASTSLWYLYALIVYFVICKIF
                     NPLALPLFVLFVLMSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATLMTCVKAVPLR
                     RHLLMASLLTVLAVGAWLFNISLLLSLVSIVVIMKLFYQYEQRFGMRSSSLLNVIGSN
                     TIAIYTTHRILVEIFSLSLIPQMNAVRWSPQVELTLLLIYPFVSLLICTVAGLLVRKL
                     SQRAFSDLLFSPPSLPATVSYSR"
     gene            31732..35178
                     /gene="mfd"
                     /locus_tag="LSX49_002390"
     CDS             31732..35178
                     /gene="mfd"
                     /locus_tag="LSX49_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBL7168791.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPSMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLENSAERFQADTLARFENRGIDPMRPLLPPQSLWLRVDELFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAIQAQQKAPLDALRKFLESFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLL
                     GERVARRRQDSRRAINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFMAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
     gene            35321..36283
                     /gene="ldtC"
                     /locus_tag="LSX49_002391"
     CDS             35321..36283
                     /gene="ldtC"
                     /locus_tag="LSX49_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HBL7168792.1"
                     /translation="MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPSAGSRLVGEN
                     KFHVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPRE
                     GIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTAN
                     IRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCI
                     RLRDDDIKTLFSQVTPGTKVNIINTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPI
                     TLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(36366..36623)
                     /gene="bhsA"
                     /locus_tag="LSX49_002392"
     CDS             complement(36366..36623)
                     /gene="bhsA"
                     /locus_tag="LSX49_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HBL7168793.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK"
BASE COUNT         9225 a         9323 c         9146 g         9021 t
ORIGIN      
        1 gtatgacaag aggcgcgaaa tatacagctc gttacaaaaa aatcaactca aaaataaaat
       61 aaaatctctg cataaacttt atggctaaat gatttcacaa caatggaaga aaaattttgt
      121 tgctcacgca atcaatcatt tcgggcgtta caactagtcc tagattatat tcgctaggta
      181 tactttattt ttaagctaat actttagctc tatttcatcg ctcctttcag cccgaactta
      241 gctttgattt ctgcgatctt cgccagagcc tgtgcacgat ttagaggcct accgcccatg
      301 acaggaagtt gttttactgg ttcaggtata gcctcaccac ggttaattcg cgcggtcata
      361 caggccagtt catcggcagc cttgcgccgt aattccgcgt cagtcaacgc attggcccgc
      421 atgttctgat acaggttggt aaccagccag tagtgcgcgt ttgatttcca cggataagac
      481 tctgcatccg gatacagacc acgcttccgg caatactcgt aaaccatatc aaccagctcg
      541 ctgacgtttg gcagcccggc ggtaacggat gcttcttccc ggcaccatgc aacaaactgc
      601 ccgggtgatg gcagaaatgg tctattctgc cgacgggcaa cacgcattcc gtcgctcacc
      661 tgctccatcg tggtgatccc gttttcccgg aaagccagaa cccactggcg gcggatttcg
      721 ttcagttcgt tctggtcacg attagccagg ctcgccggga aagttgccag taactggctg
      781 aatacaccgt tgattatctg cgctacctgc tgtacctgcg gcttttcgtc gtactgttcc
      841 ggcatgttgt tggcgatccg acgcatctgc tcacggtcaa agttaatcat ctgtgcggcg
      901 atgtttttca tagatccacc ccgtaaatcc agtctgtgtt tgtcaggtcg agttttggtt
      961 tgctagctgt cacgcctgcc tgttgcttgt tacggttgat ttcgagttgg gtccacttgt
     1021 cgcggagttt ggccggactt agcacgttac cggaccagaa gttgtcctgg catgcccagc
     1081 ggaacagcac gcacatgtcg cggtggttac gtccgtcacg ttcacgcatc aggcggatat
     1141 cgttagccca ccctgcaaaa ttcggttttc tggctgatgg cgcgatggtc ttcaccatgt
     1201 caaacatcca ctctgcggcg gtcaggtctt ctgctgtccc ccacttgctg ccgctctgaa
     1261 ttgcagcatc cggtttcacc acaggaagat cgttttctgg ttggtcagag gattcgccag
     1321 aattctcgga cgaaaaaggt tttatattgt cttttgttag tttgtctttt gtgtttacct
     1381 gattcgggta aacgccttta cctgatttgg gtaaactttt tttacctgat tcaggtaaat
     1441 ttacctcttt caggtaaact ttatttttct tacctgattc gggtaatgtt gaccattcac
     1501 tgaccacatt attaatgccg gtattccgcc cgctctgaat aaaaatccca cgctttacca
     1561 gaacactttt tgcagcagaa cacttgtgcg gcaatatccc ggttaattcg gaaagttgct
     1621 cgttgctaac ccaatccagt tttttattaa agccatatgt tttgcgcatg acagccagaa
     1681 agaccagaag ctggtgctgt gttaatccgg ccagcatcac agcttccagc aactcatttg
     1741 caatgcgcgt ataaccatca tcgagatctg ccacgcgcgg ctccttttgt gccgcatccg
     1801 gcactggaaa attgaatatc tcagcagtgt ttgccataat tcctcccgca atgagtgtgt
     1861 tacgatttgc acctgaaagt cggttctgtt ccagcagacc ggctttcgcc atttctgaac
     1921 ctgtcatatc gcccccagca tggtagtaac catcgccatc aatggaccag ccagatctgg
     1981 gtccacacga aacatcgaca caataccttc actaatttcc ttcagtttct ggtggcgtgg
     2041 tgcgttgaga atgacagcct gttttgcctc actgagttcc ttttccattt cagccaacct
     2101 agccatgaag ctatcctgct caaccaggta accgcgatat tccagcggta gtaccgccag
     2161 aattgccggg gtcagttcac gcacgttatt tcggtatttt tcagaatcga atttgttatc
     2221 gaggaagcgg aacagcttct ggcgtgcacg gctgacatca tcagggaaat cgatggtgcc
     2281 gccgccctgc tccagatact cattcacaat gagtgtggca acgacatcct gattatctac
     2341 agccgaccag gcgcggacgg catcacggat tttttcgtgg cctggcacct gttttgtttg
     2401 agaacgattt atcaccgcag tcgggctaaa tccgctagtc tgttggtatg taagtggttg
     2461 cataattgac tcctttagtt tgaattgact gttaagttga ttgcttattg ttaaagagcg
     2521 tgaaatggaa atttaagctg cgttcttttc ggtgtgtgga aacaacttcg gaagatccgg
     2581 gcgaatctgg tatgccttca ctactccacc agtagccgta acaatgctgc cgacatgttc
     2641 aggggatacc tttgctttgt tgtgaagcca cttatagacg gcctgctgtg aaacttcgca
     2701 agcagcgccc agtttctttt gtgaaccaac gatattgatc gctgttttga tagctgggtt
     2761 cataacaacc tccgtggtta atttgaatca agattaaaac tatggttgtt tttagtcaac
     2821 aaccattttc gtttgatgga ataaaacctt ggttgtacat ttggactatg aaaacaacac
     2881 tctcagaaag acttaaagaa gccagattag cgcgaggcct tacacaaaag gcgcttgggg
     2941 atttggtcgg ggttagccag gctgctattc agaaaatcga aacagggaaa gctaatcaaa
     3001 caactaaaat cgtggagatc gcgaacgctt tgggtgtgcg cgcagaatgg ttatcttctg
     3061 gcgttggaaa tatgtcagac agtacagtgc aaccaataca atcaactgtc agccattcca
     3121 aatacttcaa gattgacgtt cttgatatag aagtcagtgc tgggccggga gtcatcaacc
     3181 gtgagtttgt agaagttcta cgctcggttg agtactcgtt tgacgatgct cgtcacatgt
     3241 tcgatggtag gaaggcggaa aatatccgca tcattaacgt gcgtggtgac agcatgtcag
     3301 gaacgatcga accaggtgat ctgctgttcg ttgatatcac agttaaatct ttcgacggtg
     3361 atggtatcta tgcgtttctg tacgacgaca cagcccatgt aaagcgcctg caaatgatga
     3421 aggataagct gctggtcatc tctgataaca aaagctactc accgtgggac ccgatcgaga
     3481 aagacgagat gaaccgggtg ttcatcttcg gtaaggttat tgggagcatg ccgcagacat
     3541 ataggaagca tgggtagtac caattaaaaa ttatcaactg ggcattgtgc tcattcagta
     3601 aagaactaat tcctatcttt gctctaggta gtaatattaa gccaccgcaa taatatcttt
     3661 acctaacggc gtaagaatcc cggtcaccgt gccgggtttt cttttgccct cccctcatca
     3721 cacacaccgt taaaaaaacc accataacct cgcttcagtt atcgctatgc gattcaagtc
     3781 acaaaataaa tccatcctaa atacaaccag ttatatctaa aacaaccaat aaaacaactt
     3841 ttgttgttga cgataaaaca actatagttt taaataagtt catcgcaaca acacaacgat
     3901 acggcaacta cctgattcac cgttgcgatg accgcttaga tccgcagttt gaatttcagc
     3961 aggcttcggg gagtgcgagg ggtgaaacgg acgcgtgaac gtcggtgtga ccagctgaaa
     4021 ttaactcaac atttcatacc ttagtcgctt caacgaggcg gcttagttat gacaaccggc
     4081 ggccatccac cgcctgaata cgcgcagaag tctctatatg ttcagcagcc cagcttacgg
     4141 gcaggagttt ttatggttca tcaacattac ggaacgcaga ccgttaatcg cggtgcggtc
     4201 atgccaggaa tgctggtcaa acacaaagat ggtacctgga ctgcatcagc taatttacgc
     4261 ggacggcttt atctgcatcg cggcatcgag cgcacttata cccgtgattt gctcgtggaa
     4321 gtttttctcg acggacgcgg caacggcctg aatcactaat cccctttcct gtttacctaa
     4381 tcagcccggc atttcgcagg cgatattttc acagccattt tcaggagttc agccatgaac
     4441 gcttattaca ttcaggatcg tcttgaggct caaagctggg cgcgtcacta ccagcagatc
     4501 gcccgtgaag agaaagaggc agaactggca gacgacatgg aaaaaggtct tccacagcac
     4561 ctgtttgaat cactctgcat cgatcatttg caacgctgcg gggccagcaa aaaagccatt
     4621 acccgtgcgt ttgatgacga tgttgagttt caggagcgca tggcagaaca catccggtac
     4681 atggttgaaa ccattgctca ccaccatgtt gatattgatt cagaggtata aaacggatga
     4741 gtacagcact cgcaacgctg gctgggaagc tggctgaacg tgtcggcatg gattctgtcg
     4801 acccacagga actgatcacc actcttcgtc agacggcatt taaaggtgat gccagcgatg
     4861 cgcagttcat cgcattgctg atcgtcgcca accagtacgg ccttaatccg tggacgaaag
     4921 aaatttacgc cttccctgat aagcagaacg gcatcgttcc ggtggtgggc gttgatggct
     4981 ggtcccgcat catcaatgaa aaccagcagt ttgatggcat ggactttgag caggacaatg
     5041 aatcatgtac gtgccggatt taccgcaaag accgcaatca tccgatctgc gttaccgaat
     5101 ggatggatga atgccgccgc gaaccattca aaactcgcga aggcagagaa atcacggggc
     5161 cgtggcagtc gcatcccaaa cggatgttac ggcataaagc catgattcag tgtgcccgtc
     5221 tggccttcgg atttgctggt atctatgaca aggatgaagc cgagcgcatt gtcgaaaata
     5281 ctgcatacac tgcggaacgt cagccggaac gcgacatcac tccggttaac gatgaaacca
     5341 tgcaggagat taacactctg ctgattgccc tggacaaaac atgggatgac gacttattgc
     5401 cgctctgttc ccagatattt cgccgcgaca ttcgcgcatc gtcagaactg acacaggccg
     5461 aagcagtgaa agctcttgga ttcctgaaac agaaagccac tgagcagaag gtggcagcat
     5521 gacaccggac attatcctgc agcgtaccgg gatcgacgtg agagctgtcg aacaggggga
     5581 tgatgcatgg cacaaattac ggctcggcgt catcaccgct tcagaagttc acaacgtgat
     5641 agcaaagccc cgctcaggaa agaagtggcc tgacatgaaa atgtcctact tccacaccct
     5701 gctggctgag gtttgcaccg gtgtggctcc ggaagttaat gctaaggcgc tggcgtgggg
     5761 aaaacagtac gagaacgacg ccagaaccct gtttgaattc acttccggcg tgaatgttac
     5821 tgaatccccg atcatctatc gcgacgaaag tatgcgcacc gcctgctctc ccgatggttt
     5881 atgcagtgac ggcaatggcc ttgagctgaa atgcccgttt acctcccggg atttcatgaa
     5941 gttccggctc ggtggtttcg aggccataaa gtcggcttac atggcccagg tgcagtacag
     6001 catgtgggtg acacgaaaag atgcctggta ctttgccaac tatgacccac gaatgaagcg
     6061 tgaaggcctg cattatgtcg tggttgagcg ggatgaaaag tacatggcga gttttgacga
     6121 gatggtgccg gagttcatcg aaaaaatgga cgaagcactg gctgaaattg gttttgtatt
     6181 tggagagcaa tggcgatgac ccatcctcac gataatatcc gggtaggcgc gatcactttc
     6241 gtctactccg ttacaaagcg aggctgggta tttcacggtc tttctgttat ccgaaatccg
     6301 ctgaaagccc agcggctggc tgaggagata aataataaac ggggggcggt atgcacaaag
     6361 catctcctgt tgagttaaga acgagtattg atttggcaca tagccttgct caaattggag
     6421 tcaggtttgt gccaatacca gcagaaacag acgaagaatt tcatacgtta gccacatccc
     6481 tttcacaaaa gctggaaatg atggtggcga aagcagaagc agatgagaga gaccaggtat
     6541 gacaaccact gaatgcattt ttctggcagc gggcttcata ttctgtgtgc ttatgcttgc
     6601 cgacatgggg cttgttcagt gacacctcag caagaaaatg cccttcgcag cattgcccgt
     6661 caggctaatt ctgaaatcaa aaaagtcaga cagcagtttc cggataaaaa cgtcaatgac
     6721 atttgccgta gcgtactgaa gaagcaccgc gaaacggtaa cgctgaaggg attcacaccg
     6781 actcatttaa gcctggcaat cggcatgtta aacggcgtct ttaaggaacg atgaacatga
     6841 aaagcaaaat tatcagggag ctacaggctc cttttttatt gttcgcattc accctcaagc
     6901 gtattaacca acagttcagg gattaatgaa agatggcaga catcattgat tcagcatcag
     6961 aaatagaaga attacagcgc aacacagcaa taaaaatgcg ccgcctgaac tacctggctg
     7021 tatctgccac tcattgttgt gagtgtggcg atccgataga tgaacgaaga cgcctggccg
     7081 ttcagggttg tcggacttgc gccagttgcc agcaagatct ggagcttatc cgcaaacaaa
     7141 gggggattaa gtgatggcta acctgcaact tgctgttaaa agtgaatact tcgatgccat
     7201 gattcgcgga gagaaaacgg aagagtatcg cttgtgtaat gactactgga ataagcgaat
     7261 tatgttccgg gaatatgacc gcctgattat cacaaaggga tatccgaagc gcgacgattc
     7321 cagtcgcaga attgatgttc cgtatgacgg atatgaagtg aagacaatca cacatccgca
     7381 ctttggcgat aaaccggtaa aggtgttcgc tataaaggtg aatatcagca ctgaatatca
     7441 atccgcacaa cacaaggtca agaatgttca gagtgattga ccctaacacc tggtacgtcg
     7501 accaccacgg cactccctgc aaaatcctgc gttctaccca caacaaagtt cactacatcc
     7561 gaaaaggcag aacatgtatc gccagcatgt tccgctttaa tcatgacttt gaacctgtga
     7621 ataaagctga tgcagatcgg atagcagaag agatcgaaac ggcagaacac attaagaagt
     7681 tacgtgacat gcgcaggaaa tagaaaaatt gataaattca atactgcatt tctcagcatt
     7741 aaatttatct ctatgaccag tcaagagatg tacctgccat gagcttaata tcatgtcaga
     7801 tatatcggtc acaaactccc tcagcagcta agaggaggac aaatgtctcg actaatcact
     7861 ttacaggact gggctaaaga agaatttggg gacttagcac caagtgagcg agttctgaaa
     7921 aaatacgcgc aagggaaaat gatggcccca cccgctataa aagttggtcg ctactggatg
     7981 attgaccgaa attcccgttt tgtaggaacg cttgcagaac cgcaactccc aataaacgca
     8041 aacccaaaac tccaaaggat aatcgctgat ggctgctaga ccccgatctc acaaaatctc
     8101 tatacccaat ttatattgca aattagataa gcgaaccgga aaggtatatt ggcaatacaa
     8161 acatccacta tccggtcgtt ttcatagctt aggaactgat gagaatgaag caaaacaagt
     8221 tgctactgaa gcaaatacca ttattgctga acaacgtacc agacaaatat taagcgtcaa
     8281 tgagcgtctg gaaagaatga aaggcaggcg ctcagacatt acggtgacag aatggcttga
     8341 taaatatatt tctatccaag aggacaggct gcaacataat gaactaagac ccaactccta
     8401 tcggcaaaaa ggcaaaccca ttcgtctttt ccgtgagcat tgtggaatgc aacacctcaa
     8461 ggatattacc gcacttgata ttgccgaaat aattgatgct gtaaaggctg aaggtcataa
     8521 caggatggcg caagtcgtga gaatggtgtt gatcgacgtc ttcaaagaag cacaacacgc
     8581 aggacatgtt ccgccaggat ttaacccagc gcaggcaaca aaacaaccgc gaaatcgagt
     8641 aaaccgccaa agattgtcac tgcccgaatg gcaggcaata tttgacagcg taagcagacg
     8701 gcagccctat ttaaaatgcg gcatgctact tgctcttgtt actggacaac gtttaggcga
     8761 tatctgcaat ttgaaattct ctgatatatg ggacgacatg ttgcacatta ctcaggaaaa
     8821 aaccggttca aaacttgcta ttccgcttaa cctgaaatgc gatgctctga atattaccct
     8881 tcgtgaagtt atatctcagt gcagggatgc tgttgttagt aaatatctgg tccattaccg
     8941 tcacactacc tctcaagcaa acagaggaga ccaggtttct gcaaatactc tgacaacggc
     9001 ttttaaaaag gcccgggaaa aatgtggcat aaaatgggag caaggaactg cgcccacatt
     9061 tcatgagcag cgatctctgt cagaacggtt atatcgggaa cagggtctgg atacgcaaaa
     9121 gttgttaggc cataaatcca gaaaaatgac cgaccgatac aatgatgatc gtggtaaaga
     9181 ctggattatc gtagatatca aaacagcata gaaaatagcc agttttgggg aagggttttg
     9241 gggaaagttt tggggaagat tttacatcat cataaaacaa cgggcgtgtt atacgcccgt
     9301 ttcaatattt aacacatgta gtgattacat attcttgatg atcgcgtcac caaactctga
     9361 acatttcagc agtttagcgc cttccatcag acgttcgaag tcataggtta cggtcttggc
     9421 attgattgcg ccttccatac ctttaacaat caggtcagcc gcttcagtcc aacccatatg
     9481 gcgcagcatc atctcagcgg agagaataat agagcctggg tttactttgt cctgtccggc
     9541 atatttcggc gcagtaccgt gggtggcttc aaacagggcg cattcgtcac cgatgtttgc
     9601 gccaggggcg ataccgatac caccaacctg cgctgccagg gcgtcagaaa tgtagtcacc
     9661 gttcaggttc atacaggcga taacatcata ttcagccgga cgcagcagga tctgttgcag
     9721 gaatgcatca gcaatcacgt ctttaatgac gatctctttg ccggtattcg ggtttttaac
     9781 tttcagccac gggccgccgt cgatcagttc accgccaaat tcttcacgcg ccagttggta
     9841 gccccagtct ttaaacgcgc cttcggtgaa cttcatgatg ttgcctttgt gcaccagggt
     9901 cacagagtca cgatcgttag caattgcgta ttcgatcgct gcacgaacca gacgtttggt
     9961 gccttcttcc gaacacggct taataccgat accgcaatgt tccgggaagc gaattttctt
    10021 cacgcccatc tcttcacgca ggaatttaat cactttctca gcgtcggcag agtctgcttt
    10081 ccattcgata cccgcataaa tgtcttccga gttttcacgg aagataacca tatcggtcag
    10141 ttcagggtgt ttaaccgggc ttggagtgcc ctgatagtaa cgtaccggac gcaggcagat
    10201 gtagagatcc agttcctggc gcagggcaac gttcagagag cgaataccgc caccaaccgg
    10261 agtggtcagc gggcctttaa tggcaacgcg atattcacga atcagatcaa gggtttcagc
    10321 aggcaaccag acgtcctgac cataaacctg tgtggatttt tcaccggtgt aaatttccat
    10381 ccaggagatt ttacgctcgc ctttataggc tttctcgact gcagcgtcga ccactttcag
    10441 catggctggg gttacatcta caccgattcc atcaccttca atgtaaggga taatcggatt
    10501 ttcaggaacg ttgagtttgc cgttttgcag ggtgatcttc ttgccttgtg ccggaacaac
    10561 tactttactt tccattcacc tctccttcga gcgctactgg tttgctcgtc tgccaccacg
    10621 ttgcatatgc gtttgcgtcc tgcgatacgg atgctttaga gcaatttttt gttaatgatt
    10681 tgtaattagc ttgtcaatac taccctattg tttgccgtca tgaaagatgc gcgttattag
    10741 gctataatgc ggcaattcat aatctctgaa aataccatgc aaaaaacttc ttttagaaat
    10801 caccaggtta agcgattcag ctcgcaacgt tctaccaggc gtaaacctga caaccagccc
    10861 acgcgtgtga tcctgttcaa taaaccctac gatgttcttc cgcagttcac cgatgaagcc
    10921 ggacgcaaaa cattaaaaga attcatcccg gttcaggggg tgtatgcggc aggtcgtctc
    10981 gaccgcgaca gcgaagggtt actggtgctg accaataacg gcgcgttgca ggcgcgttta
    11041 acccagccgg gtaaacgcac cggaaaaatc tattatgtgc aggtggaagg tattcccaca
    11101 caagacgcac ttgaagcctt gcgcaatggc gtaaccttaa atgatggccc taccctgccc
    11161 gcaggcgcgg agctggttga agaacccgcg tggttatggc cgcggaatcc accaattcgt
    11221 gagcgcaaaa gtattcccac cagctggctg aagatcacct tatatgaagg acgtaatcgc
    11281 caggtgcgcc gcatgaccgc ccatgttggt ttccccacgc tgcgactgat tcgctatgcg
    11341 atgggggatt actctttgga taatcttgcc aatggcgaat ggcgagacgc gacagattaa
    11401 ggatgcaaaa tgtttaaacc gcacgttacc gttgcttgcg tggtgcacgc agaaggcaaa
    11461 tttttagtcg ttgaagagac gattaatggt aaagcgttat ggaaccaacc tgccgggcac
    11521 ctggaagccg atgaaacctt agtggaagcc gccgcccgtg agctgtggga agaaaccggc
    11581 attagcgcgc agccgcaaca ctttattcgt atgcatcagt ggattgcgcc cgataaaacg
    11641 ccgtttttgc gtttcctctt tgccattgag cttgagcaaa tatgcccgac gcagcctcat
    11701 gacagcgata tcgactgctg ccgttgggtc agcgccgaag aaattttaca ggcgtcaaat
    11761 cttcgttcgc cgctggtggc ggaaagtatt cgttgttatc aaagcgggca acgctatccg
    11821 ctggagatga ttggcgattt taactggcct tttacaaagg gtgtcatcta aaaggctgcg
    11881 tgatagaata cgccgccttg aagttcaatg tcgtgagtga tccaatgtct gaaaccgcaa
    11941 aaaaagtaat cgtcggcatg tccggcggtg tcgattcctc cgtttctgcc tggctgttac
    12001 aacaacaggg atatcaggtc gaaggcctgt ttatgaagaa ctgggaagaa gacgacggtg
    12061 aggaatattg cacagcggca gcggatctgg ctgatgccca ggctgtctgc gacaagctcg
    12121 gcattgaact gcacaccgtt aactttgctg ccgagtactg ggacaacgtc ttcgaactgt
    12181 tccttgccga atataaagcc ggtcgcacgc cgaatccgga tattctgtgc aacaaagaga
    12241 tcaaatttaa agctttcctc gaatttgccg ccgaagattt aggtgccgat tatatcgcta
    12301 ccggtcatta cgtacgtcgg gcagatgtcg atggcaagag ccgcctgctg cgtggtctgg
    12361 acagcaataa agaccagagc tacttccttt atacgctcag ccatgagcag attgcgcaaa
    12421 gcctgttccc ggtcggcgaa ctggaaaaac cgcaggtgcg taagattgct gaagatcttg
    12481 gtctggtcac cgcgaagaaa aaagactcta ccggcatttg cttcattggc gaacgtaaat
    12541 tccgcgagtt cctgggccgt tatctcccgg cgcaaccggg caaaatcatt accgtcgatg
    12601 gcgatgaaat tggtgagcac caggggctga tgtatcacac cctcggtcag cgtaaaggtc
    12661 tgggtatcgg tggcaccaaa gacggcaccg aagaaccgtg gtatgtggtc gataaagacg
    12721 tcgaaaacaa cattctgatt gttgcgcaag gccatgaaca cccgcgtctg atgtctgtcg
    12781 gtctgattgc ccagcagctg cactgggtcg atcgcgaacc gttcaccggt actatgcgtt
    12841 gcacagtaaa aacccgctat cgccagaccg acatcccgtg caccgtcaag gcgctggacg
    12901 atgatcgcat tgaagtgatt ttcgatgagc cggttgccgc cgtgacgccg ggccagtctg
    12961 ccgttttcta taacggtgaa gtgtgcctcg gtggcggtat tattgagcag cgtctgccgc
    13021 tgccggtctg attattatct ttacttaaaa caaggaagca gtgaacgtgg caaagaatta
    13081 ctatgacatc accctcgccc tggccggtat ttgtcagtcg gcacgcctgg tgcaacaact
    13141 cgctcaccag gggcattgtg atggcgatgc gctacacgtc tcactcaaca gtattatcga
    13201 tatgaacccc agctcaacgc tggcggtttt tggcggcagc gaagccaacc tgcgcgtcgg
    13261 gctggaaacc ttgctcggcg tactcaatgc cagcagtcgc caaggcttaa acgccgaatt
    13321 aacccgctac acactcagtc tgatggtgct tgagcgcaaa ctctcctcag cgaaaggtgc
    13381 gctcgacact ctgggcaacc ggatcaacgg cctgcaacgc cagctcgaac acttcgattt
    13441 acagtccgaa acgctgatga gcgcgatggc tgccatctat gttgatgtta tcagcccgct
    13501 tggcccgcgc attcaggtca cgggttcccc tgctgtactg caaagcccac aggtgcaggc
    13561 gaaagttcgc gcaaccctgc tggcaggcat tcgcgccgcc gtgctctggc accaggtcgg
    13621 cggcggtcgt ctgcaactga tgttttctcg taatcgcctg accactcagg caaaacaaat
    13681 tcttgctcat ttaaccccgg agttgtgatc tatggaatta tcctcactga ccgccgtttc
    13741 ccctgtcgat ggacgctacg gcgataaagt cagcgcgctg cgcgggattt tcagcgaata
    13801 cggtttgctg aaattccgtg tacaagttga agtacgttgg ctgcaaaaac tggccgcgca
    13861 cgcagcgatc aaggaagttc ctgcttttgc tgccgacgca atcggttacc ttgatgcaat
    13921 tgtcgccagt ttcagcgaag aagatgcagc acgcatcaaa accatcgagc gtaccactaa
    13981 ccacgacgtt aaagcggttg agtatttcct gaaagaaaaa gtggcggata tcccggaact
    14041 gcacgcggtt tctgaattca tccattttgc ctgtacttcg gaagatatca ataacctctc
    14101 ccacgcatta atgctgaaaa ccgcgcgtga tgaagtgatc ctgccgtact ggcgtcaact
    14161 gattgatggc attaaagatc tcgccgttca gtatcgcgat atcccgctgc tgtcccgtac
    14221 ccacggtcag ccagccacgc cgtcaaccat tggtaaagag atggctaacg tcgcctaccg
    14281 tatggagcgc cagtaccgcc agcttaacca ggtggagatc ctcggcaaaa tcaacggcgc
    14341 tgtcggtaac tacaacgccc acatcgccgc ttacccggaa gttgactggc atcagttcag
    14401 cgaagagttc gtcacctcgc tgggtattca gtggaacccg tacaccaccc agatcgaacc
    14461 gcacgactac attgccgaac tgtttgattg cgttgcgcgc ttcaacacca ttctgatcga
    14521 ctttgaccgt gacgtctggg gttatatcgc ccttaaccac ttcaaacaga aaaccattgc
    14581 tggtgagatt ggttcttcca ccatgccgca taaagttaac ccgatcgact tcgaaaactc
    14641 cgaagggaac ctgggccttt ccaacgcggt attgcagcac ctggcaagca aactgccagt
    14701 ttcccgctgg cagcgtgacc tgaccgactc caccgtgctg cgtaacctcg gcgtgggtat
    14761 cggttatgcg ctgattgcgt atcaatccac cctgaaaggc gtgagcaaac tggaagtgaa
    14821 ccatgaccat ctgctggagg agctggatca caactgggaa gtgctggctg agccaatcca
    14881 gacagttatg cgtcgctatg gcatcgaaaa accgtacgag aagctgaaag agctgactcg
    14941 cggtaagcgc gttgacgccg aaggcatgaa gcaatttatc gacggtctcg cgctgccaga
    15001 agaagagaaa gcccgcctga aagcgatgac gccggctaac tatattggtc gcgccatcac
    15061 catggttgat gagctgaaat aagcctcaaa tcagtgccgg atggcgatgc tgtccggcct
    15121 gcttattaag attatccgct ttttattttt tcactttacc tccccttccc gctggtttat
    15181 ttaatgttta cccccataac cacataatcg cgttacacta ttttaataat taagacaggg
    15241 agaaataaaa atgcgcgtac tggttgttga agacaatgcg ttgttacgtc accatcttaa
    15301 agttcagata caggatgctg gtcatcaggt cgatgacgca gaagatgcca aagaagccga
    15361 ttattatctc aatgaacatt taccggatat tgcgattgtc gatctcggat tgcctgacga
    15421 ggatggtctg tcactgattc gccgctggcg tagcaatgat gtttcactgc cgattctggt
    15481 attaaccgcc cgtgagagct ggcaggacaa agtcgaagta ttaagtgccg gtgctgatga
    15541 ttacgtgact aaaccgtttc atattgaaga ggtgatggcg cgaatgcagg cattaatgcg
    15601 gcgtaatagc ggtctggctt cacaggtcat ttcgctacca ccgtttcagg ttgatctctc
    15661 ccgccgtgaa ttatctatta atgacgaagt gatcaaactg accgcgttcg aatacaccat
    15721 tatggaaacg ttgatacgca ataatggcaa agtggtcagc aaagattcgt taatgctaca
    15781 actctacccg gatgcggagc tgcgggaaag ccataccatt gatgtactga tgggacgtct
    15841 gcgcaaaaaa attcaggcac aatatccgca agaagtgatt accaccgttc gcggccaggg
    15901 ctatctgttc gaattgcgct gatgaaaaaa ttactgcgtc tttttttccc gctctcgctg
    15961 cgggtacgtt ttctgttagc aacggcagca gtagtattgg tgctttcgct tgcctacgga
    16021 atggttgcgc tgatcggtta tagcgtcagt ttcgataaaa ccacgtttcg gctgttacgt
    16081 ggcgagagca atctgttcta tacccttgcg aagtgggaaa acaataagtt gcatgtcgag
    16141 ttacccgaaa atatcgacaa gcaaagcccc acgatgacac taatttatga tgagaacggg
    16201 cagcttttat gggcgcaacg tgacgtgccc tggctgatga agatgatcca gcccgactgg
    16261 ctaaaatcga acggttttca tgaaattgaa gcggatgtta acgataccag cctcttgctg
    16321 agtggagatc attcgataca gcaacagttg caggaagtgc gggaagatga tgacgacgcg
    16381 gagatgaccc actcggtggc ggtaaacgtc tacccggcaa catcgcggat gccaaagtta
    16441 accattgtgg tggtggatac cattccggtg gagctaaaaa gttcctatat ggtctggagc
    16501 tggtttatct atgtgctctc agccaatctg ctgttagtga tcccgctgct gtgggtcgcc
    16561 gcctggtgga gtttacgccc catcgaagcc ctggcaaaag aagtccgcga actggaagaa
    16621 cataaccgcg aattgctcaa tccagccaca acgcgggaac tgactagtct ggtacgaaac
    16681 ctgaaccgac tgttaaaaag tgaacgcgaa cgttacgaca aatatcgtac gacgctcacc
    16741 gacctgaccc atagtctgaa aacgccactg gcggtgctgc aaagtacgct gcgttctctg
    16801 cgtagtgaga agatgagcgt cagtgatgct gagccggtaa tgctggagca aatcagccgc
    16861 atttcacagc aaattggcta ctacctgcat cgtgccagta tgcgcggcgg gacattgctt
    16921 agccgcgagc tgcatccggt cgccccactg ctggacaatc tcacctcggc gctgaacaaa
    16981 gtgtatcaac gcaaaggggt caatatctct ctcgatattt cgccagagat cagctttgtc
    17041 ggtgagcaga acgattttgt cgaggtgatg ggcaacgtgc tggataatgc ctgtaaatat
    17101 tgcctcgagt ttgtcgaaat atctgcaagg caaacagacg agcatctcta tattgtggtc
    17161 gaggatgatg gccccggtat tccattaagc aagcgagagg tcattttcga ccgtggtcaa
    17221 cgggttgata ctttacgccc tgggcaaggt gtagggctgg cggtagcccg cgaaatcacc
    17281 gagcaatatg agggtaaaat cgtcgccgga gagagcatgc tgggcggtgc gcggatggag
    17341 gtgatttttg gtcgccagca ttctgcaccg aaagatgaat aaatatgtcc atacttcacg
    17401 cattacgtta agcatccgtt ataatcggtt gcagatacca gcctgtggat gcttaacatg
    17461 gaataccaac tcactcttaa ctggcccgat tttcttgaac gtcactggca gaaacgtccg
    17521 gtggtgttaa aacgcggctt taataatttt attgacccga tctctccaga cgagttggcg
    17581 ggtttggcga tggaaagcga agtcgacagt cgactggtca gtcatcagga tggcaaatgg
    17641 caggtcagcc acggtccatt cgaaagctac gatcatctcg gtgaaactaa ctggtcattg
    17701 ttagtgcaag cagtgaacca ctggcatgag ccgaccgccg cgctaatgcg accgttccgt
    17761 gaactaccgg actggcgtat tgatgatctg atgatctctt tttctgtacc gggcggcggc
    17821 gtcggcccgc atctcgatca gtacgacgtg tttatcattc agggtaccgg tcgtcgtcgc
    17881 tggcgagtgg gcgaaaagct gcaaatgaaa cagcactgcc ctcacccgga tctgttacag
    17941 gtcgatccgt tcgaagccat catcgatgaa gagctggagc ctggcgatat tctttatatt
    18001 ccgccaggat tcccgcatga aggctacgcg ctggaaaatg cgatgaacta ttccgtgggt
    18061 tttcgcgcgc caaatacgcg ggaactgatt agcggatttg ccgattatgt gctgcaacgt
    18121 gaactgggcg gcaactacta cagcgatcct gatgttccac ctcgcgctca tcctgcggac
    18181 gttctgccgc aagagatgga taaactgcgt gagatgatgc tcgaattgat caaccagcca
    18241 gaacatttta agcaatggtt tggcgagttt atatcccagt cacgtcatga actggatatc
    18301 gcgccgccag agccgcctta tcagccggat gaaatctacg atgcgctgaa acaaggtgat
    18361 gtgctggtgc gcctgggggg tctgcgcgta ttgcgcattg gcgacgacgt gtatgccaat
    18421 ggtgagaaga tcgattcccc gcaccgtccg gcactggatg cgctcgccag caacattgcg
    18481 ctgaccgcgg agaattttgg cgatgcgctg gaagatccgt cattcctcgc gatgctcgcg
    18541 gcgctggtca atagcggata ctggttcttc gaagggtaag tttggattta agccggatgc
    18601 ggcatcacat gccgcatccc ttttcgctta cttccgttgc gccgtcaact cggcaatacg
    18661 gacgatcacc tgcaccgctt tttccatacc ttccagagtc acaaactcat gcttaccatg
    18721 atagttgtaa ccgccagtga acaggttcgg gcacggtaat cccataaacg acaactgcgc
    18781 gccgtcggta ccgccgcgga tcggtttcag ttccggttca atatcgcagt cacgcatcgc
    18841 ctgctgggcg atatcgagaa tatgcggatg ctcaaccact ttctcgcgca tattgtagta
    18901 actgtcttca atcaccagtt caatgtagca atcaggatgt aaccctttgc ccactttttt
    18961 ggcgatctcc atcattttac gtttacgcgc ttcaaactgt ttacggtcga aatcacggat
    19021 gatgtagtgc atatcggccc gttcaacggt gcctttcatg ctcgccaggt gatagaaacc
    19081 ttcatagcct tctgtcattt ccgggctttc atccgccgga acttccgcat gaatacgtgc
    19141 cgccagcgac agcgcattta ccatcactcc tttcgccgtg cccgggtgaa cattgttacc
    19201 gacaattttg atattgaccg acgcggcgtt gaagttttca aactccagtt cacctacgcc
    19261 accaccatca acggtgtaag cccagcgggc atcgaaggcg tcaacatcaa aatgtttcgc
    19321 ccctttgccc acttcttcat ccggggtaaa ggcgacgcga atatcaccat gcggaatgtt
    19381 tttttgttgc aataccgcca gcgcggtcat gatttctgca atacctgctt tgtcatcggc
    19441 acctaacaag gttttaccat cggtggtaat cagcgtctga cccagtagct gatgcagcac
    19501 cgggaacata accggtgata aaacttcatc gccgataccc agcgcaatat cgccaccgcg
    19561 atagttttca acaatttgcg gattcacatt tttgccgctg caatccggtg aggtatccac
    19621 atgagaaata aagccaatcg ccgggatatc gccagggacg ttagccggta acgtcgccat
    19681 caaagtgccc ttctcactta aggtcacatt gataagcccc atctcttcga gctgctcttt
    19741 cagcagatgc aataacttcc attggccttc cgtgctggga acctgtctca cccctgcctt
    19801 tgattgggta tcaagagaca cgtagttcaa aaatcgctca agtagtttat ccatgtagtc
    19861 accctcactt tttgtgacaa cattattaag aagcaagaaa agacaaatat tgcgtcaggt
    19921 cacttttagc cctgcaagcg ggaatattta tcagcattac cttaatgaat ataaagctaa
    19981 gccagtaatt cacaacaaag attggcgatt caagcggttt gccgtagaat taccgccctc
    20041 attaagagtc accaaggtgg ttaaccacaa accccgcatc ggtaagccat ccgttgcgtt
    20101 tacatgggac agagtaaaaa attgaataaa caaccgagtt cgctttcacc gctggtgcaa
    20161 ttggcgggaa ttcgcaaatg ctttgatggt aaagaggtca ttccccagct ggatctgact
    20221 atcaacaatg gcgagttcct cacgctgctt ggcccttctg gctgcggtaa aacaaccgtt
    20281 cttcgcctga ttgcaggtct ggaaactgtt gattccggac gcatcatgct ggataacgag
    20341 gacatcaccc acgttccggc ggaaaaccgc tatgtgaaca ctgttttcca aagctacgca
    20401 cttttccccc acatgaccgt gttcgaaaat gtggcctttg ggttgcgcat gcaaaaaacc
    20461 cccgcagctg aaattacgcc ccgcgtgatg gaagccctgc ggatggtgca gctggaaacc
    20521 ttcgctcaac gcaaaccgca tcagctctct ggtggtcaac agcaacgcgt cgccattgct
    20581 cgcgcggtgg ttaacaagcc tcgtctgttg ttgctggatg agtcgctctc agcgctggat
    20641 tacaaactgc gtaagcaaat gcagaacgag ctgaaagcgt tacagcgtaa gcttggcatt
    20701 acattcgtgt tcgtaactca cgaccaggaa gaagcactta ccatgtcgga caggatcgtg
    20761 gtgatgcgcg atggtcgcat tgagcaagac ggcacgccgc gtgaaatcta cgaagagccg
    20821 aaaaacctat ttgttgccgg gtttattggc gaaatcaata tgtttaacgc cactgtcatc
    20881 gaacgtctcg acgagcagcg cgtacgcgcc aacgttgaag gccgcgaatg taatatctac
    20941 gttaacttcg ccgttgaacc ggggcaaaaa ctgcatgttc tgctgcgccc ggaagactta
    21001 cgtgttgaag agattaacga cgacaaccac gccgaagggc tgattggtta cgttcgcgag
    21061 cgtaactaca aaggcatgac gctggagtcg gttgttgagc tggaaaatgg caagatggtg
    21121 atggtcagcg aattcttcaa tgaagacgat cctgactttg accactctct cgaccaaaaa
    21181 atggccatta attgggtaga aagctgggag gtcgtactgg ctgatgaaga acacaagtaa
    21241 gttccagaat gtagtgattg tcactattgt cggttggctt gtgttgttta tctttctgcc
    21301 caacctgatg atcattggca ccagcttttt gacccgcgac gacgccagtt tcgtcaaaat
    21361 ggtctttacg ctggataact acacgcgtct gctcgatccg ctctattttg aagtgctatt
    21421 gcactcgctg aatatggcgc tgatcgccac cctcgcctgc ctggtgctgg gctatccttt
    21481 tgcctggttt ctggcgaagc tgccacacaa ggtgcgtccg ctgctgctgt ttctgctgat
    21541 tgttccgttc tggaccaact cattgattcg tatttacggg ctgaaaattt tcctcagcac
    21601 caaaggctat ctcaacgagt ttttgctctg gctgggcgtt atcgatacac caattcgcat
    21661 catgttcacg cctagtgcgg tgattatcgg tctggtttac attctgctgc cgtttatggt
    21721 gatgccgctg tactccagta tcgaaaaact ggataagccg ttgcttgagg cggcgcgcga
    21781 tctcggtgcc agcaagttgc agacctttat tcgcatcatt atcccactga cgatgccggg
    21841 aattattgcc ggatgtctgc tggtgatgct gccagcgatg ggcctgttct atgtgtccga
    21901 cctgatgggc ggtgcgaaaa acctgctgat cggtaacgtc atcaaggtac agttcctcaa
    21961 tattcgtgac tggccgtttg gtgcagccac cagcattacg ctgactatcg taatgggcct
    22021 gatgttgctg gtttactggc gcgcttctcg tttgctgaat aagaaggtgg aactcgaatg
    22081 atcggtcgac tgcttcgcgg cggttttatg accgctatct acgcgtacct gtatatccca
    22141 atcattattt tgattgtgaa ctcctttaac agctcgcgct ttggcatcaa ctggcagggt
    22201 tttaccacca aatggtatag cctgctgatg aacaacgaca gcctgttaca ggcagcgcag
    22261 cattcactta caatggcggt gttttcggcg acgtttgcta cgcttatcgg ttcactgacg
    22321 gcagttgcgc tgtaccgtta tcgctttcgt ggtaagccgt tcgttagcgg aatgctgttt
    22381 gtggtgatga tgtcaccaga tatcgtaatg gcgatttcgc tgctggtgct gtttatgctg
    22441 ctgggtattc agcttggctt ctggtcgctg ctgttctcgc atatcacctt ctgcctgcca
    22501 tttgtggtag tgacagtgta ttcgcgcctg aaaggttttg acgtgcgaat gctggaagcg
    22561 gcgaaagatc tcggtgccag cgaatttacc attctgcgaa aaatcattct gccactggca
    22621 atgccagcgg tagcggcggg ctgggtgtta agctttaccc tgtcgatgga cgacgtggtg
    22681 gtttcttcgt ttgtcaccgg gccgagttat gaaattctgc cgttaaaaat ttattcgatg
    22741 gtcaaagtcg gcgtatcgcc ggaagttaac gcgctggcaa ccatattact ggtgctgtcg
    22801 ctggtgatgg taattgccag ccagcttatt gctcgtgata aaacgaaagg taacacaggg
    22861 gacgttaaat gaaaaaatgg tcacgccacc tgctcgcggc gggtgctctg gcactgggca
    22921 tgagcgccgc tcacgccgat gacaacaaca cgctgtattt ctacaactgg accgagtacg
    22981 tgccgccagg actgcttgaa cagttcacca aagaaaccgg tattaaggtt atctattcga
    23041 cttacgagtc gaacgaaacc atgtacgcga agctgaaaac gtacaaagac ggtgcctatg
    23101 acctggtggt tccttcaacc tattacgtcg ataaaatgcg taaagaaggg atgatccaga
    23161 agatcgacaa gtcgaagtta agcaatttca gcaacctcga tccagacatg ctcaacaagc
    23221 cgtttgaccc gaataacgac tattccattc cgtatatctg gggtgcgacg gcgattggcg
    23281 ttaacggtga tgcggtggat ccgaaatctg tcaccagctg ggccgatctg tggaagcctg
    23341 agtacaaagg cagcctgctg ctgaccgacg atgcccgtga agtgttccag atggcgctgc
    23401 gtaagctggg ctactccggt aacaccaccg atccgaaaga gattgaagct gcatacaacg
    23461 agctgaaaaa gctgatgcca aacgtcgcgg cgtttaactc cgataacccg gcgaacccgt
    23521 atatggaagg cgaagttaac ctcggcatga tctggaacgg ttctgctttc gttgcacgcc
    23581 aggcgggtac gccaattgat gtggtgtggc cgaaagaagg cggtattttc tggatggaca
    23641 gcctggcgat cccggcaaat gccaaaaaca aagaaggcgc gctgaaattg atcaacttcc
    23701 tgctgcgccc ggatgtggca aaacaggttg ctgaaactat cggttatcca acgccaaacc
    23761 ttgcggcgcg taagctgtta agtccggaag tggcgaacga taaaacgctc tacccggatg
    23821 ctgaaaccat taaaaatggt gaatggcaga atgacgttgg cgcagccagc agcatttatg
    23881 aagagtatta tcagaagctg aaagcaggac gttaattcag caagcgggcg gtgatattac
    23941 cgcccgtttt ttatttagca aggatgtggc taatgagcca ggacagtaga gttttctttc
    24001 gtatattctt cggtatcggt ctggtactga tcctcatttc tgttgttatc ttttataacc
    24061 agttcaccta tagcaaagac gcgattcata ctgaaggcgt cattgttgat accgtctggc
    24121 actccagtca ttctcatcgc acgggtaaaa atggttcgtg gtatcccgtc gttgcctttc
    24181 gtccgacgcc agattacacg ctaattttca attcgagtat tggcagcgat ttttatgaag
    24241 gcagcgaagg cgataaagtt aatgtttatt attctccagg acatcctgaa aaggctgaga
    24301 taaataaccc gtgggttaat ttttttaaat gggggtttat cggcattatg ggcgttattt
    24361 ttatctccgt cggtttatta atcagtatgc cctcctctaa aaagacacgc aggaaacgga
    24421 agtcccgccc atgaaaaaaa tcataatatt gctcagttta ctgatactcc tgcctctgac
    24481 ggcaaccagt aagcccttaa ttccaataat gaagacactt tttacggatg ttaccggtac
    24541 tgtaccagat gctgaagaga tcgcgcataa agccgagctt tttcgccaac aaaccggagt
    24601 tgcaccgttt attgtggttt tacccgacat taataatgaa gccagtctca ggcaaaatgg
    24661 caaagcgatg ctggcgcatg cggcatcttc aatgagtaat gtaaaaggaa gtgttctgtt
    24721 actctttact acccgcgagc cacggttaat tatgataacc aacggccagg ttgaaagcgg
    24781 tctggacgat aaacatctcg gccttctggt agaaaatcac acgctggctt atttacatgc
    24841 ggacctctgg tatcagggta tcaataatgc attggctgtt ttacaagcac agatattaaa
    24901 acaaccgacg ccaccactga catattatcc gcatcccgga caacagcatg aaaatgatcc
    24961 acccggcagt accacgacat taggcctttt tgcctgggca gttgcattca tcgtctttgc
    25021 tgcatttttt aactacacaa cgcgccttta ttatgcgtta aaatttgcag tggcgatggc
    25081 tgttgccaat atgggttatc aggctttatg tttgtatatc gataacagct ttgcgattac
    25141 cagaatatcg ccactctggg cagggctgat tggtgtctgt acgtttattg ccgcgttact
    25201 atggacgagt aaacggtaaa agaggcagta aagttcgcgt gtattatgcc ggatgcggcg
    25261 cgaacgcctt atccggccca caaaacccgc aaattcaatt aattgcgccc cttcacaggc
    25321 ctgacaagcg tagcgcatca ggcaattttt cccgctttat aatcccttca gcaacttttc
    25381 aacaaactct ggcaccacct ggcttgccgg accgtaatat ttctcggcaa attcattacc
    25441 aacctgactc ggttcaagat tcagttccac ggtgtgcgcg ccatgcagtt tcgcttcgtg
    25501 aacaaaccca gccgccggat aaacatgccc cgaagtacca atggcaatga aaatatcggc
    25561 catcgacaac gccatataaa tttcatccat gccgagtggc atttcgccaa accacactac
    25621 gtgcgggcgc aagggtgccg ggaactggca acaatggcat ttatcttctg gcgtaacgtc
    25681 tccggtccag tcgaggacct ggccactttg cgaacaacgt actttcagca attccccatg
    25741 catatgaatc acattggtat tgcctgcgcg ttcatgcagg ttatcgatat tttgcgtcac
    25801 cagcaaaaag cgatcgccga gagcatcttg cagtttcgcc agcgcaagat gtgcagcgtt
    25861 aggctgaatt tctggctgct gcaactgtcg acgacgggcg ttataaaacg tttgcaccag
    25921 ttcaggatcg cgatcaaaac cttccggcgt tgccacatct tcaacccgat gttcttccca
    25981 caggccatct gcggcgcgaa aggtacgaat acctgattcc gcagaaatcc ctgcccctgt
    26041 cagtacgagt actcttggtt tttccattgc ttccggcacc actttatctc tgaaaaaaat
    26101 acgctgacgc aaacgctcgc gcaggcggcg tttattttta cgaaaacgac ttaaccgatg
    26161 accccgacgc gacagcatag caacctctgt tgattaatcg gttagatgta ggaaggccgc
    26221 accacgcatt cctcccgcat caccgtggcg cgcgcgttca atgcgcggaa cacgagctac
    26281 aggtaagaga tgacgaggca acctttccgc cagttgcgtt gtgattgccg ggaaattcga
    26341 taagccacca ccaatgacga ccaggtcagg gtcaacaatg gtcaggatat ttcccagaca
    26401 aaccgctaat aaatccagat aacgctcaac gtgcgccctt gcctgctcat cgccttgatc
    26461 ataaagcgca atgatctcag gagcctgcaa cggttgatga taatagtgtt gatacagcca
    26521 cgcaaaaccg cgaccagaca gataattttc aatgcagcca tgctgaccac agccgcagcg
    26581 gcgtaacggg aaatccagcc ccatcatggt taacgcatca accggcagac gcatatggcc
    26641 aaactcgccg gtaatatagc ttttaccggt aattggttta ccgttgaaaa tcagcccgcc
    26701 gccaacgccg gtgccgagaa tcaaccccat caccagtgga tattgagtaa attcatcatc
    26761 ccatgcttca gaaagggcaa aacagttggc atcgttatca aggcgtacat cgcgatcaag
    26821 acgtgcgctc aggtcggcac gcagcggttt accgctggca gcagggacat tggcggcata
    26881 cagcgtacca tcttctgttt ccggcatacc cggaatacca atgccgacag aacctttaca
    26941 gccaaaacgt tggtcagctt cggctaccag ctcgcacact gcatctaaaa atgcgtcata
    27001 gctgtcacgc ggtgtcggca cccgcttttc ccactgcaac tgccgaccgc tatcaaacac
    27061 gcctagcgca atttttgttc caccaatatc aaacccgtaa tacattgccg ctccttgttt
    27121 taatgtactg cctttactgg ccgctaagga ctcgcgcagg gtcaatatta ctggcgcgcc
    27181 gcgccggata ccaacttgcc aaaagactca gcaacaatgc tgtgaccagt acgtagaaga
    27241 cgtccagcca gtgcaattcc gatggcagga agtcaataaa atagatatcg ctggagagga
    27301 actgatggcc gatcagcttt tcaatccact caataatcgg ggtaagttgc agtgaaacaa
    27361 ctacgccgat aatcacacca cacaggctgc cgaacagccc tgccagcaat ccataccaga
    27421 caaagatggc gcggattaaa ccatctttcg cacccaacgt tcttaatact gcgatatcgc
    27481 cactcttgtc tttcaccgcc atcactaagg tggagacgat gttgaaacag gccacaccaa
    27541 tcaccagtac catcgccaga tacataatgg cgcggatcat ctgaatatcg cgatacatat
    27601 agccgtaagt accaatccag cttttaatat aaacatagct gttggtcact tcacccgcat
    27661 cgcgtaccag cttattggcg ttgaaaacat ccgtcatttt aagggcaata cctgacacgc
    27721 tggaacccat atcaagatat tgctgagcat cggccagcgg gatcatggca aaactgtgat
    27781 cgagttgacc actcaactgc aaaataccgg caacgtgcaa acgcacacgt tttggctgca
    27841 tcagtttatg ctcgggattc gaatttggga tcataatcga cacccaatcc ccctgcttca
    27901 ctttcagcgc atccgccacg cctttgccga tgataatttg ctgttcgcct gctttaaaat
    27961 tgctccacgc atcgtcctgg acaaacgagg gtaatgcgct caaacgctgt tcctgttgcg
    28021 ggttaacgcc cttgacctgg attgcgcgca gattcgcgcc actttccacc agcccggtga
    28081 aattgatata cggcgcagcg gcggcaatgc ccggcacttt ctgcacgtta tccagtgctt
    28141 cctgccagtt ggtccacggc tgatctaccg cctcaatttc accgtgcggt actaccgcca
    28201 gaatgcggtt attcagttcg cgttcaaagc cgttcatcgc gcttaagccg acgatcaata
    28261 ccgccacgcc gagggcaatg ccaatggtag aaatgacgga gatcaacgac accatgccgc
    28321 cgcgtcgccg tccgcggcta aaacgcaggc caatcaataa cgataaaggc atcgccatta
    28381 ctccgccccc atcaggctca gttccgccgt cagacgtcca tcacgcattt ctagttggcg
    28441 gctcatacgt ttcgccagtt gcaggtcgtg agtaaccacc aggaaggcgg tgccctgcaa
    28501 gcgattcaat tccccaagca actggaagat gctgtcggcg ttacgtgcat cgaggttacc
    28561 agtaggttca tccgccagta ccagccgcgg gttattgacc agcgcacggg caatcgccac
    28621 acgctggcgt tcgccgccag aaagttcaga tgggcggtga ttcgcacgat gctccagccc
    28681 caccgctttt aacatctcca gcgcacggct gttgatttca gcgggctttt tcttgccaat
    28741 caacagcggc atagccacgt tttccagggc ggtaaaatcc ggcagcaggt ggtgaaactg
    28801 ataaataaat cccagcttct ggttgcgcag ttctgctttc gccgccgaag acagtttgct
    28861 catcggttga ccgttaaaga tcacatcgcc ggaggttggc gtatccagcc cgcctaacag
    28921 gtgcagcaag gtgcttttac cggaaccaga gctgccgacg atcgccatca tttcaccttc
    28981 gcccacgctg aaactgacat tgtgcagtac atcggtttgc acactgcctt cctgatagcg
    29041 tttgcacagg ttgtcgcatt gcaacaggat cttattcata acgtaaagcc tcagcgggtt
    29101 gagtggcggc agcgcgccag gaagggtaaa gcgtagacag cagcgcgata gccatcgcca
    29161 ccagcgcaat aacaatgacc tgtaaaggct cgatagcgac cggcagcgcc gcgccatcaa
    29221 gcaggacgcc gattatcggc atcagattat tcaactggct ggcaagcagt gcgccaagcg
    29281 ccgctccgag gatcgcaccg ataatcccgg cgctggcccc ttgcaccata aagaccatca
    29341 tgatttgccg cggagtcagc ccctgagtct gaagaatggc cacttcgccc tgcttctcca
    29401 tcaccatcag tcccagcgag gtaataatgt taaacgccgc aacggcgaca atcaggctca
    29461 gcagcaagcc catcatattt ttttccatgc gtacggcctg gaacagctcg cctttacggt
    29521 cacgccagtc ctgccatttg ctgccttcag gcagtttttg ctgacttaat gagtcgactt
    29581 tcagcggctc atccagccac aaacgccagc cggtaatatt gcctgccgga taacgcatca
    29641 gacgcgaggc atcctcaata ttcaccagca tttcatagcc atcgacttca ctgttggcgg
    29701 cgaaagtgcc aatcacattg aacaggcgct gacttggaat acgccccatc ggcgtgaact
    29761 ggctagcaga tggcaccatc acgcggattt gatcaccgcg attgacgccc aactgtgagg
    29821 caagctgttc accgaggatg acattatatt tccccggctc gaggtcagtt tgtttcacat
    29881 tgaccagata cggcgttagt ggatcttttt gcgccgggtc gatacccagc atcaccccga
    29941 ccgccacgct gcgcgcgctt tgcagtacca catcaccggt agtaataggt gcgacgcgat
    30001 taacgccgtc cagtttgact gccgtttccg ggagttgctg cgggttaaga gagccatgct
    30061 cagaagagag aattgcctgt ggcatcaggc caaggatgtt gttttgcagc tcgcgctcaa
    30121 agccgttcat cactgacaat actgtgacca gcgccatcac cccgagggta atgccgatgg
    30181 tagaaagcca ggagacgaaa cgaccgaagc gatccgctgc acgcccacgc atgtaacgca
    30241 ggccaataaa tagagcgaca ggttggtaca tgaaatccgt ctggttgctg tagcaaagac
    30301 acgagtatat aagcgaaagc aggatgggta aacgtctgaa ctgtaagtga tcgtcagggc
    30361 taatctgaaa agtaccagca aatcaatcgg ctaaagtgcc tcattttatc atcggccatg
    30421 tggcctgatc tttatctgaa aaataaccaa atacagacag atacgcatta caccacgcga
    30481 ctcgccccgc aggatcaacc gcatgttaaa taaaaagagc gtgttgtccc gatgaaacaa
    30541 aaagagctat ggattaacca gatcaaaggg ttatgtattt gtctggtggt gatttatcac
    30601 tcggtcatta ccttttatcc gcatctgacc acttttcagc atccgttatc ggaagtcctg
    30661 agcaaatgct ggatctattt caatctttac cttgcaccct ttcgtatgcc ggtttttttc
    30721 tttatctctg gctatttgat tcgccgctat atcgacagcg taccgtgggg aaattgtctc
    30781 gataaacgca tctggaacat cttctgggtg ctggcgcttt ggggcgtggt gcagtggctg
    30841 gcgttaagtg cgctgaacca gtggctggca cctgagcgcg atttaagcaa tgcctccaat
    30901 gccgcttatg ccgattccac cggtgagttc ctgcacggga tgatcaccgc cagcaccagc
    30961 ttgtggtatc tgtatgcgtt aattgtctat ttcgtgatat gtaaaatttt taaccccctg
    31021 gccctgccgt tatttgttct gtttgtactg atgagtgtgg ctgttaattt cgtacccaca
    31081 ccgtggtggg gaatgaacag tgtgatccgc aatttgcctt attacagcct tggcgcatgg
    31141 tttggcgcaa cattaatgac ctgtgttaaa gcggtaccgt tgcgccgcca tctgctgatg
    31201 gcttctttgc tgaccgttct ggcggtcggt gcctggttgt ttaatatctc gctgctgttg
    31261 tcgctggtat cgattgtggt aatcatgaag ctgttttatc agtacgagca gcgtttcggt
    31321 atgcgttcct ccagcctgct gaatgtgatt ggctccaaca ccattgctat ctataccacc
    31381 catcgcattc tggtagaaat attcagctta agcctgattc cgcaaatgaa cgcggtacgc
    31441 tggtcgccgc aagtcgaact gacgctcctg ctgatttacc cctttgtcag tttgttgatt
    31501 tgtactgttg cgggcttgct ggtaagaaaa ctttcacagc gcgcattcag cgatctgttg
    31561 ttctccccgc cttctctgcc cgctaccgtc agttactccc gctaagccat cgccccagcc
    31621 ggggcgattc aatttgctaa accatgtcga ttacggataa tgaacagcat tgcttatcag
    31681 agatatgccc catatgttga ggcatatcct aacgagaatc tgacaaccgt tatgcctgaa
    31741 caatatcgtt atacgctgcc cgtcaaagcg ggtgagcagc gtctgctggg cgagttaacc
    31801 ggcgctgcct gcgcgacgct ggtagcagaa attgccgaac gtcacgccgg tccggtggta
    31861 ctcattgcac cagatatgca aaatgctctg cgtttgcatg atgaaatcag ccagttcacc
    31921 gatcagatgg tgatgaatct ggcggactgg gaaaccctcc cttacgacag tttttcgcct
    31981 catcaggaca ttatctcctc gcgtctttcc accctttacc agttaccatc gatgcagcgt
    32041 ggcgtactga ttgttccggt gaatacgctt atgcagcgcg tttgcccgca cagctttctc
    32101 cacggtcatg cgctggtgat gaaaaaaggt cagcgcctgt cacgagatgc attacgaacc
    32161 caactggaca gcgccggtta tcgccatgtt gaccaggtga tggagcacgg cgaatacgcc
    32221 acgcgcggcg cgttgttgga tctcttcccg atggggagtg agctgcctta tcgtcttgat
    32281 ttctttgatg atgaaatcga cagcctgcgg gtgtttgacg tcgatagcca gcgcacgctg
    32341 gaggaagtag aagcgatcaa tctgttgccc gcgcacgaat ttccgaccga taaagcggca
    32401 attgaactgt tccgcagcca gtggcgtgat accttcgaag tgaagcgcga cccggaacat
    32461 atttatcagc aagtgagtaa aggcacatta cctgccggga tcgagtactg gcagccgcta
    32521 ttcttcagcg aaccgctgcc gccactgttc agttatttcc ctgccaatac gctgttggtg
    32581 aatactggcg atctggaaaa cagtgccgaa cgtttccagg ctgacacgct cgcgcgtttt
    32641 gagaatcgcg gcatcgaccc aatgcgccca ctgttgccac cacaatcgct ctggctgcgg
    32701 gtggatgagc tcttctcaga gctgaaaaac tggccccgtg tgcagctaaa aactgaacat
    32761 ttaccgacaa aagcagcgaa tgccaattta ggtttccaga aactgccaga cctggccatt
    32821 caggcacaac aaaaagcgcc gctggatgcg ctgcgtaagt tcctcgagtc tttcgacggt
    32881 ccggtggtgt tctcggtaga aagtgaaggc cgccgtgaag cgttgggtga actgctcgcg
    32941 cgaattaaaa ttgctccgca acgcattatg cgtcttgatg aagccagcga ccgtgggcgt
    33001 tatctgatga ttggcgctgc agagcatggt tttgtcgata cggtacgtaa tctggcgctg
    33061 atttgcgaaa gcgatctgct cggtgaacgc gttgcccgtc gtcgtcagga ttctcgccgc
    33121 gccatcaacc ccgatacact gatccgtaac cttgcggagc tgcatattgg tcagccggtg
    33181 gtccatctgg agcacggcgt cggtcgttat gccggaatga ccacgctcga agctggaggc
    33241 attactggcg agtatttgat gctcacctat gccaacgacg ccaaactgta tgttccggtg
    33301 tcgtcactgc atctgattag ccgttacgcg ggtggcgcag aagaaaacgc accactgcat
    33361 aaacttggtg gcgatgcctg gtcacgcgcg cggcagaaag cggcggaaaa agtgcgtgat
    33421 gtggcggcgg aattgctgga tatctacgcg caacgcgccg ccaaagaggg cttcgcgttt
    33481 aaacacgatc gcgagcagta tcagttgttc tgcgacagct tcccgtttga aaccacgccg
    33541 gatcaggcgc aggccattaa tgcggtgctt agtgacatgt gtcagccgct ggcaatggat
    33601 cgtctggtgt gcggcgatgt tggctttggt aaaacagaag tggcgatgcg cgccgctttc
    33661 atggcggtag ataaccacaa acaggtggcg gtgctggtgc ctaccaccct tctcgcgcag
    33721 cagcattacg acaacttccg cgaccgtttc gccaactggc cggtacgtat cgaaatgatc
    33781 tcccgtttcc gcagcgccaa agagcagacg caaatccttg cggaagtggc ggaagggaaa
    33841 attgatattc tgatcggtac gcacaaactg ctgcaaagtg acgtcaagtt taaagattta
    33901 ggcctgctga ttgtcgatga agaacaccgc ttcggggtgc gtcataaaga gcgcattaaa
    33961 gcgatgcgcg cgaacgtgga tattctgacg cttaccgcaa cgccgatccc acgtacgctg
    34021 aatatggcaa tgagcggaat gcgcgatctg tcgattatcg ccacgccgcc cgcccgtcgt
    34081 ctggcagtta aaacctttgt ccgtgagtat gacagtctgg tggtccggga ggcgatcctg
    34141 cgtgaaattt tgcgcggagg acaggtttat tatctctaca atgatgtgga aaacatccag
    34201 aaagccgccg aacggctggc agaactggta cctgaagcgc ggattgctat cggtcacggg
    34261 caaatgcgtg agcgcgaact ggaacgggtg atgaatgatt tccatcatca acgtttcaac
    34321 gtgctggttt gtaccaccat tatcgaaacc gggatcgaca ttcctaccgc caacaccatt
    34381 atcattgaac gcgcggatca cttcggtctg gcacagttgc accagttgcg cggtcgcgtc
    34441 gggcgttcgc accaccaggc atatgcatgg ctgctgacgc cgcatccaaa agcgatgact
    34501 accgatgcgc aaaaacgtct tgaagcgatt gcctcgctgg aagatctcgg tgcaggtttt
    34561 gcgctggcaa cgcacgatct ggagatccgc ggcgcgggtg aactgcttgg cgaagaacaa
    34621 agcggctcaa tggaaaccat cggtttctcg ctgtatatgg agttgctgga aaacgccgtc
    34681 gatgcgctga aagccggacg cgagccgtcg ctggaagatc tcaccagcca gcaaacagaa
    34741 gtcgagctgc ggatgccgtc gctattgcca gatgatttca tccctgacgt gaacacgcgt
    34801 ctgtcgttct acaaacgtat tgccagcgcc aaaacggaaa acgaactgga agagatcaaa
    34861 gtcgagctta tcgatcgctt cggcctgctg ccggatccgg cgcgtaccct gctggatatt
    34921 gcccgtctgc gccagcaagc gcagaaactg gggatcagga agctggaagg taatgagaaa
    34981 ggcggcgtga tcgaatttgc cgagaagaat cacgttaatc cggcctggtt gattggtttg
    35041 ctgcaaaaac agccgcagca ttaccgcctt gatggtccga cgcgtctgaa gtttattcag
    35101 gatttgagcg agcggaaaac gcgtatcgaa tgggtacgcc agtttatgcg tgaactggaa
    35161 gagaacgcga tcgcttaatg gtaaatcggg ggcgtttctg cgcccccatc tgcaatattt
    35221 acaaattctt tgcacttccc tgcattatcc gacactgtca ccctccataa ttcagactta
    35281 cctttttatt acaataacct tatatttatt atggactttg gtgatgatca aaacgcgttt
    35341 ttctcgctgg ctaacatttt ttacgttcgc cgctgccgtg gcgctggcgc taccggcaaa
    35401 agccaacacc tggccgctgc cgtcagcagg cagtcgtctg gttggtgaaa acaaatttca
    35461 tgttgtggaa aatgacggtg gttctctgga agccatcgcc aaaaaatata acgtcggctt
    35521 tctcgctctg ttacaggcta accccggcgt tgatccttac gtaccgcgcg cgggtagcgt
    35581 gttaacgatc ccgttgcaaa ccctacttcc agacgcgccg cgcgaaggca ttgtgatcaa
    35641 cattgcggag ctgcgtctct attattatcc gccgggaaaa aattcggtaa ccgtatatcc
    35701 catcggcatt ggtcaattag gtggtgacac gctgacaccg acaatggtga ccaccgtttc
    35761 tgacaagcgt gcaaacccaa cctggacgcc aacggcaaac attcgcgcgc ggtataaggc
    35821 acagggaatt gagttgcctg cggtagttcc ggctggaccg gataacccaa tgggccatca
    35881 tgcgattcgt ctggcggcct atggcggcgt ttatttgctt cacggtacga acgctgattt
    35941 cggcattggc atgcgggtaa gttctggctg tattcgtctg cgggatgacg atatcaaaac
    36001 actctttagc caggtcaccc caggcaccaa agtgaatatc atcaacaccc cgattaaagt
    36061 ctctgccgaa ccaaacggtg cgcgtctggt tgaagtacat cagccgctgt cagagaagat
    36121 tgatgacgat ccgcagctgc tgccaattac gctgaatagc gcaatgcaat catttaaaga
    36181 tgcagcacaa actgacgctg aagtgatgca acatgtgatg gatgtccgtt ccgggatgcc
    36241 ggtggatgtc cgccgtcatc aagtgagccc acaaactctg taaagctcgg ataaaaaaat
    36301 ccccgcgaca cggcatgtcg cggggaaaaa aacaagcagt agcaggcatt aatgagggtt
    36361 aatgcttatt tataaattac tgctgttcca tggagggtat tcggaccggt tacagaagta
    36421 atacggaaag attttgcgcc catctcatcc gctttttgcg ccagctgctc ttccagcgat
    36481 cccagatttg tccccgcgtt agcactgata gtaccgactt tttgttggcc ttctggcgtt
    36541 gactgaactt cgacagccgc aaagctggca aatgacatgg agcttaaaat cgccgcagcg
    36601 atgagggttt ttacgttttt cataatagtg gccttatgca gatgaatgac gtcgcaagca
    36661 attacttaac gatcgataac taaatgatag atgtgatctg gatcacatac aagat
//
LOCUS       DAFGPF010000044        36241 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFGPF010000044 DAFGPF010000000
VERSION     DAFGPF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36241
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.044"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(145..432)
                     /locus_tag="LSX49_002393"
     CDS             complement(145..432)
                     /locus_tag="LSX49_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HBL7168794.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTVESQKSVEDEDIIRLVAER"
     gene            complement(507..650)
                     /gene="mgrB"
                     /locus_tag="LSX49_002394"
     CDS             complement(507..650)
                     /gene="mgrB"
                     /locus_tag="LSX49_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HBL7168795.1"
                     /translation="MKKFRWVALVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            809..1048
                     /locus_tag="LSX49_002395"
     CDS             809..1048
                     /locus_tag="LSX49_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168796.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(1192..1983)
                     /gene="kdgR"
                     /locus_tag="LSX49_002396"
     CDS             complement(1192..1983)
                     /gene="kdgR"
                     /locus_tag="LSX49_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HBL7168797.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     MQILEGVEYKRSTERTIISTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF"
     gene            2160..3533
                     /locus_tag="LSX49_002397"
     CDS             2160..3533
                     /locus_tag="LSX49_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7168798.1"
                     /translation="MPKVQADGLPLPLRYGAILTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIGAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLIAAAILAVIAACVSGLRI
                     TQPRSRA"
     gene            complement(3579..4460)
                     /gene="htpX"
                     /locus_tag="LSX49_002398"
     CDS             complement(3579..4460)
                     /gene="htpX"
                     /locus_tag="LSX49_002398"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HBL7168799.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(4652..6700)
                     /gene="prc"
                     /locus_tag="LSX49_002399"
     CDS             complement(4652..6700)
                     /gene="prc"
                     /locus_tag="LSX49_002399"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HBL7168800.1"
                     /translation="MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTA
                     FEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
                     "
     gene            complement(6720..7418)
                     /gene="proQ"
                     /locus_tag="LSX49_002400"
     CDS             complement(6720..7418)
                     /gene="proQ"
                     /locus_tag="LSX49_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707288.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HBL7168801.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKSGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(7515..8012)
                     /gene="msrC"
                     /locus_tag="LSX49_002401"
     CDS             complement(7515..8012)
                     /gene="msrC"
                     /locus_tag="LSX49_002401"
                     /EC_number="1.8.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="HBL7168802.1"
                     /translation="MNKAEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDVNW
                     AGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHAFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLEKVLATTDYKKFF
                     ASVAG"
     gene            8142..9425
                     /gene="yebS"
                     /locus_tag="LSX49_002402"
     CDS             8142..9425
                     /gene="yebS"
                     /locus_tag="LSX49_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HBL7168803.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDAITGAMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLLLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            9394..12027
                     /gene="yebT"
                     /locus_tag="LSX49_002403"
     CDS             9394..12027
                     /gene="yebT"
                     /locus_tag="LSX49_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HBL7168804.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIAGWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLSSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVIIKLELPGGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEMTVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLQEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPRRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            12107..13546
                     /gene="rsmF"
                     /locus_tag="LSX49_002404"
     CDS             12107..13546
                     /gene="rsmF"
                     /locus_tag="LSX49_002404"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HBL7168805.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPVLPAPKYKVGNFPFSPVKD
                     REAGQIRQAAASVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALASPDNVNAFELTPQEAEEWYRGRDVYPHAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTGNA"
     gene            13663..13899
                     /locus_tag="LSX49_002405"
     CDS             13663..13899
                     /locus_tag="LSX49_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HBL7168806.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA"
     gene            14004..14195
                     /locus_tag="LSX49_002406"
     CDS             14004..14195
                     /locus_tag="LSX49_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HBL7168807.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRHGGCF
                     PIEDFIDGFWRPAQEYGDF"
     gene            complement(14196..14852)
                     /gene="pphA"
                     /locus_tag="LSX49_002407"
     CDS             complement(14196..14852)
                     /gene="pphA"
                     /locus_tag="LSX49_002407"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HBL7168808.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVRAVRGNHEQMAMDALASRQMSLWLMNGGD
                     WFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERQKGQGIAGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTLVQLQ
                     "
     gene            complement(15247..15588)
                     /locus_tag="LSX49_002408"
     CDS             complement(15247..15588)
                     /locus_tag="LSX49_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HBL7168809.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTKAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(15601..16473)
                     /gene="copD"
                     /locus_tag="LSX49_002409"
     CDS             complement(15601..16473)
                     /gene="copD"
                     /locus_tag="LSX49_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HBL7168810.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLTKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWSDVFSPNIWLAVLQTQFGGVWLWQIVLAL
                     VTLIVALMQPQNMPRLLFMLTTAQFILLAGVGHATLNEGVTAKIHQTNHAIHLICAAA
                     WFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTHWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(16477..16851)
                     /gene="yobA"
                     /locus_tag="LSX49_002410"
     CDS             complement(16477..16851)
                     /gene="yobA"
                     /locus_tag="LSX49_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HBL7168811.1"
                     /translation="MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYT
                     VDWHVVSVDGHKTKGHYTFSVK"
     gene            16990..17220
                     /gene="holE"
                     /locus_tag="LSX49_002411"
     CDS             16990..17220
                     /gene="holE"
                     /locus_tag="LSX49_002411"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HBL7168812.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            17322..17978
                     /locus_tag="LSX49_002412"
     CDS             17322..17978
                     /locus_tag="LSX49_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBL7168813.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSYGACLGRRSRTITVVDEQPQGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEHGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            18002..18664
                     /gene="exoX"
                     /locus_tag="LSX49_002413"
     CDS             18002..18664
                     /gene="exoX"
                     /locus_tag="LSX49_002413"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HBL7168814.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLE
                     NT"
     gene            complement(18661..20721)
                     /gene="ptrB"
                     /locus_tag="LSX49_002414"
     CDS             complement(18661..20721)
                     /gene="ptrB"
                     /locus_tag="LSX49_002414"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HBL7168815.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVDPSFVWANDSWTFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEIADAEPFVFLPRRKDHEYSLD
                     HYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRDNIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDNHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPAD"
     gene            complement(20930..21589)
                     /locus_tag="LSX49_002415"
     CDS             complement(20930..21589)
                     /locus_tag="LSX49_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HBL7168816.1"
                     /translation="MANWLNQLQSLLGQSRSSTSSSADQGLGKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ERLILALVFAAKSDGHIDAKERAAIDLQLREAGVEEKGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVREGIERDLEQQKRTLA
                     E"
     gene            complement(21916..22272)
                     /locus_tag="LSX49_002416"
     CDS             complement(21916..22272)
                     /locus_tag="LSX49_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HBL7168817.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(22339..22629)
                     /gene="yebG"
                     /locus_tag="LSX49_002417"
     CDS             complement(22339..22629)
                     /gene="yebG"
                     /locus_tag="LSX49_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HBL7168818.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            22763..23941
                     /gene="purT"
                     /locus_tag="LSX49_002418"
     CDS             22763..23941
                     /gene="purT"
                     /locus_tag="LSX49_002418"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HBL7168819.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     ADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEELQLPTSTYRFADSENLFREAVAAIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAHAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(23997..24638)
                     /gene="kdgA"
                     /locus_tag="LSX49_002419"
                     /gene_synonym="eda"
     CDS             complement(23997..24638)
                     /gene="kdgA"
                     /locus_tag="LSX49_002419"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBL7168820.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPIAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(24675..26486)
                     /gene="edd"
                     /locus_tag="LSX49_002420"
     CDS             complement(24675..26486)
                     /gene="edd"
                     /locus_tag="LSX49_002420"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HBL7168821.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDNNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(26721..28196)
                     /gene="zwf"
                     /locus_tag="LSX49_002421"
     CDS             complement(26721..28196)
                     /gene="zwf"
                     /locus_tag="LSX49_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBL7168822.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            28534..29403
                     /gene="hexR"
                     /locus_tag="LSX49_002422"
                     /gene_synonym="yebK"
     CDS             28534..29403
                     /gene="hexR"
                     /locus_tag="LSX49_002422"
                     /gene_synonym="yebK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HBL7168823.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAALALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGTKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            29531..30973
                     /gene="pyk"
                     /locus_tag="LSX49_002423"
     CDS             29531..30973
                     /gene="pyk"
                     /locus_tag="LSX49_002423"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBL7168824.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQEAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(31105..32076)
                     /gene="lpxM"
                     /locus_tag="LSX49_002424"
                     /gene_synonym="msbB"
     CDS             complement(31105..32076)
                     /gene="lpxM"
                     /locus_tag="LSX49_002424"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HBL7168825.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMVMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(32195..33517)
                     /gene="mepM"
                     /locus_tag="LSX49_002425"
     CDS             complement(32195..33517)
                     /gene="mepM"
                     /locus_tag="LSX49_002425"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HBL7168826.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(33533..34465)
                     /gene="znuA"
                     /locus_tag="LSX49_002426"
     CDS             complement(33533..34465)
                     /gene="znuA"
                     /locus_tag="LSX49_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HBL7168827.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETQVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQV
                     TIAQLEDVKPLLMKSIHDDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLNQLANQYASCLKGD"
     gene            34544..35299
                     /gene="znuC"
                     /locus_tag="LSX49_002427"
     CDS             34544..35299
                     /gene="znuC"
                     /locus_tag="LSX49_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HBL7168828.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            35296..36081
                     /gene="znuB"
                     /locus_tag="LSX49_002428"
     CDS             35296..36081
                     /gene="znuB"
                     /locus_tag="LSX49_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HBL7168829.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAFYDTPAGPSVVLCAALLFIISMMKKQAS"
BASE COUNT         8674 a         9297 c         8925 g         9345 t
ORIGIN      
        1 tcccgttacg caaataaata atatgataat tatttgaagt cagaccagag ttttaatttg
       61 aagcagttgc accatgacag tgcgtataat cagcatgaat tgagtaaccc ttcaacgacg
      121 gggttactca agattgagga aggattatcg ttcggcgacc agacgaataa tatcttcgtc
      181 ttcaaccgat ttttgactct caacggtctt tttatctgct ttctcaggtt cgtttgcttc
      241 gcacaaacga cgtaacagtg cattttgacg tttttgctga tccagcaacg cctcaagcag
      301 ttcaatctgt tcgttagtcc gtgaactggc acgattgata aaaaaccaca agatgagccc
      361 gataagaaga accaccaccg atacaaccaa agacgcaatg ttcatcacgc ctgaatttac
      421 aacttcgttc atttcaccac ctctgagtag aggcgctatt ctaccactgc tggagaggaa
      481 gaaaatccag tgctgaaaaa atgatatcac cacgggataa actggttaat ggcacaaatt
      541 ccgctgaaaa attgtacatc ctgatcgcac atcatgttga atacctgcgc ccaaagcagc
      601 aagcaagcca acaccacgac aaccagagcg acccatcgaa actttttcac tccaatctcc
      661 gtttcaccta ccttatgtca ttaaactagc atgcgttagt taaacagcgc ctaactatgt
      721 cgatattcgt gctttttcag aatgagtcgc ttgcttcagc gcatattgcc gctacgatta
      781 agcgaacata aaaagagaag aggttgtaat gcgattcatc attcgcacag ttatgctgat
      841 agcactggta tggataggat tattactcag cggatatggc gttttgattg gaagcaaaga
      901 gaatgccgcg ggattaggtt tgcaatgtac ctatctgacc gccagaggca ccagcacggt
      961 acaatacctg cacactaaaa gtggttttct ggggataaca gattgcccgt tgttacgcaa
     1021 aagcaatatt gtggtcgata atggttaagg gtaataaata accagattct cactcatgag
     1081 taaaatattc ttatcgcaag tgcgtttaat ataacgccac cttcaacttt atttttctca
     1141 tgctaaataa agaacctgtc tgtttgatat tcagacaggt tcttactctc atcagaacgg
     1201 atagtcgtga taacccattt gggcagaaat tttgcgcgcc gcggtatgca acattgcgac
     1261 atattcctgt aaacgctctt cagagaaacg caacgtcggg aaggagatgc tcagaccggc
     1321 aatgaccacg ccaaagcgat caaataccgg aaccgcaatg caacgcagtc cttcttcctg
     1381 ctcttcgtta tcttcgccat acccctgctc gcgcacctgg tccagaacgg gtaataacgc
     1441 ttctgtactg atgatggtcc gttcggtact gcgtttatac tccacgccct caagaatttg
     1501 catcacttca tcgcgatcgc gccatgccag cagtacctta ccaatcgcgg tgctgtacag
     1561 cggattacga cgcccaatcc gtgaatacat gcgcaaattg tacattgagt caattttgtg
     1621 gatgtaaaca atactgtctt cgtccagtgc gccgaggtgg atagtttctt tggtcaggcg
     1681 ggagatctca cgcatctgga tatctgcgct acgaattaaa tcgacgtttt gcaacgcgcg
     1741 ggcgcccagt tcaaacaatt tcagggtcag cgaatatttc tccgactccc cttcctgcgc
     1801 cacataacct aaggttttca tggtctgtaa aaagcgataa acggtgcttt ttgacatcat
     1861 gacgcgctgc gacaactcgg ttatccctat ttcgcgctct tcacccagcg cctgcaaaat
     1921 gccaaaaact tttagcacgg aagatacaga atcaggctgt ttatccagat ctgcgttagc
     1981 catttatcac ctcattgcga gtgttttata aaaatcagaa ctgtttttta ttataatttc
     2041 gcacctgggt ggtcgcaatc catcttttgc cggttagtta caattctgcg acatccaccg
     2101 tgaatatcag tgctagaatc atacccctgt tgattattca ccaaagatat aaaattccta
     2161 tgccaaaagt tcaggccgac ggcctgccat tgcccctgcg atacggtgcg atattaacca
     2221 ttgtgattgg tatttcgatg gctgtccttg acggcgcaat cgccaacgtc gccttgccaa
     2281 caatcgctac ggaccttcat gccacgccgg ccagttccat ctgggtagtg aacgcctatc
     2341 aaatcgccat tgtcatctcc ctgctctcgt tttcgtttct gggcgatatg tttggctatc
     2401 gacgtattta taaatgcggt ctggtcgttt ttctgttgtc ttcactgttc tgcgcccttt
     2461 ctgattcgct gcaaatgctc acccttgcgc gtgtcataca aggtttcggc ggtgcagcgt
     2521 tgatgagcgt taataccgca cttatccgcc tgatctatcc acaacgtttt ctgggtagag
     2581 ggatgggcat aaactcgttt attgttgccg tctcttctgc tgccgggccg acaattgctg
     2641 cagcaatcct ctccatcgca tcctggaaat ggttattttt aatcaacgta ccgttgggta
     2701 ttatcgccct gcttctggcg atgcgttttc tgccacccaa tggttctcgc gccagtaaac
     2761 cccgtttcga cctgcccagc gccgtgatga acgcgttaac cttcggcctg cttattactg
     2821 cattgagtgg tttcgctcag gggcaatcgc tgacattgat tggtgcggaa ctggtggtaa
     2881 tggttgtcgt tggtattttc tttattcgcc gccagctttc tcttcccgta ccgctgctac
     2941 cggtggattt actgcgtatc ccgctgtttt cactttctat ttgcacatct gtttgctctt
     3001 tctgcgcaca aatgctggca atggtttccc ttccctttta cctgcaaacc gtgctcgggc
     3061 gtagtgaagt cgaaacaggt ttacttctga caccgtggcc gttagcaacg atggttatgg
     3121 ctccactggc aggctatttg attgaacgcg tacatgcagg attgctgggt gctttagggt
     3181 tattcatcat ggctgcgggg cttttttccc tggttctgct gccagcgtca cctgcggata
     3241 tcaatattat ctggccgatg atcttatgtg gtgctggatt tggcttgttc cagtcaccca
     3301 ataaccacac cattattacc tccgctcctc gcgaacgtag cggtggagcc agtggcatgt
     3361 tagggacggc tcgtcttctg ggtcagagta gcggcgcggc tctggtagcg ctgatgctaa
     3421 atcagtttgg tgataatggt acgcacgtct cgctgatagc tgcggctatt ctggcagtga
     3481 ttgctgcctg tgtcagtggt ttacgtatca ctcagccacg atccagggca taaaaaaagc
     3541 gcgtcgatca ggacgcgctt tttagtattt acgtcatatt acttcaggta ttcacccgta
     3601 cgcagagctt caatacgttt atccagcggc gggtgggtca tgaacaactc actgagcgat
     3661 ttcgacttac cgttaatgca gaaagccatc atgctggttg cttcttgcgg ttcatagctg
     3721 gttttcaggc gttgcagcgc ggcaatcatt ttctcgcgac caaccagttt tgctgaaccc
     3781 gcatcagcat ggaattcacg atgacgcgag aaccacatgg tgataatgct cgccagaata
     3841 ccaaacacca gttccagaac cgttgcaacc gcaaagtaga tcagcgggtt gccgttgctc
     3901 tcttcacctt catcacggtt tccgcccata aaacccgcgg caagctgcgc cagaatacgg
     3961 gaaataaaga taacgaaggt gttcaccacg ccctgaatca gcgtcatggt gaccatatca
     4021 ccattggcga tgtggctgat ttcgtgagca attaccgcct cggcttcatc cgggctcatg
     4081 ttctgcagca aaccagtgct gacagcaacc agagaggcat cacggcgcgc accagttgca
     4141 aaagcattga tgtccggcgc atggtagata gccacttgcg gcatagcgat ccccgcctga
     4201 cgagcctggg ttgctacagt attgaccagc caacgttccc tttcgttacg cggttgctcg
     4261 atcacttccc cgccaacaga tcgtaatgcc atccatttgg acatcagaag cgaaacgaag
     4321 gaaccaccaa aaccgaacag caaggccatg atcatcagcc cctgaacgct gctcgactgt
     4381 atccctgtca ggctcagtac cagcccgaaa acgaccatta cggccaggtt cgttagcagg
     4441 aagagcgcga ttcgcatcat aattttcttt ttacctcagt ttaacaaaac gcaatatgcg
     4501 atacccacat cgtatgggtt acgcgactat tttcaagtct ggatagtgcg taagtcacca
     4561 gaaagacaca actttacatt ttgtagcatc tgatttacgg catcttgccg ctgttaaaaa
     4621 atcaggcaca atttcttgtg cctgatagat attacttgac gggagcgggt tgttccgcgg
     4681 gtctggcttt ttcaagcttc gccagatcga gtgcgatatt caccgtctca tccagataag
     4741 gatctggctc ctggtaatct ttcggtagat catccagttt cttcaactcc ggtttacctt
     4801 cgcgtttaaa gcgttcgttc aaacgcgcca gacgcgtcgc atcatcttca ttattctctt
     4861 tctcacgcac agcgtaattc agagaaacga tattgcgctt gtccttcata gcgttgaagc
     4921 gcgcgatatc cttcatgatg ttctggaact caggatcttt cgcgatacgc gcattatgtt
     4981 ccttcagcag ctccggttca aaggccgtta aatctcctga tttcacataa gtcgcggcat
     5041 caatgctatc ccacggcagc gcgttatctt cgaatttctc acccgtttcc gtttcttcat
     5101 tacccgtcgg catgatgatg tctggcgtta cgcctttacg ttgcgtactg ccgccgttaa
     5161 cgcgatagaa cttctggatc gtgtactgca cagaacccag cgctggccat tcaggacgta
     5221 acatctgatc gtaaatacgg ttcaatgaac ggtactgctg aacggtgcct ttaccaaacg
     5281 tcggttcacc cacaaccagg gcacgaccgt aatcctgcat tgccgcggca aagatttctg
     5341 aagccgaagc actgaagcgg tcaaccagca ccaccagcgg gcctttatag aagacctgtc
     5401 cgtcggtgtc gctgtcttca cgaaccttgc cgttgttatc gcggacctga acaatcgggc
     5461 cggatggaat gaacagaccg gagagcgata cggcttcagt caacgcccca ccaccattgc
     5521 tacgcaggtc gataatcaca ctgctgacat tctgtttttc cagtttctgc agttgcactt
     5581 tgacatcgtc tgtcaaaccc acatagaagc ctggaatatc cagcacgccg actttctctt
     5641 taccgacggt cttcaccgac attttaaccg cgcggtcttc gagacgaata cgttcacggg
     5701 tcaacgttac agtacgcgtc ttggtccctt taccagcagg taaaatttcc agacgaactt
     5761 tactgccctt aggcccttta attaaggcca ccacatcatc aagacgccag ccaatcacgt
     5821 caaccatcgg cttgcctgtt tgaccaacac cgacaatttt gtcaccaacg ctgatagctt
     5881 tgctcttcgc tgccggacct cctgccacca tcgaattgat aacggtgtag tcatcatcca
     5941 tttgcagcac tgcgccaata ccttccagcg acaaactcat ttcagtgttg aactgttcgg
     6001 tattacgcgg ggaaagatag ttggtatgcg ggtcgatttc acgtgcaaac gccgtcattg
     6061 ccagcgagaa aacatcttcg ctgttggttt gcgccagacg acgaatggca aatttgtagc
     6121 ggcgagtcag ggtttcacga atttccttat ccgtttttcc tgtcagcttc aggcttaact
     6181 cgtcgaattt gactttactg tcccacagcg cgttcaactc agcctcgttt ttcggccagg
     6241 gcgctttgct gcggtcaagg ttataagtgt cgttgccggt gaaatccatc ggcttttcca
     6301 gtaccgacaa agcgtactgg taacgttcaa aacggcgctt ttgcgccaga ttgtagagat
     6361 cgtagaaaac gtcgagttta cctgaacgca gttcatcgcc taactcagtt ttctttttcg
     6421 cgaactgttc aacatcgctt gccagcagca cattatggct gtaatcgagc agattcaggt
     6481 agcggtcaaa gattttggcc gaaaatgcct gatcgaggtc gaactggcga taatgagaac
     6541 gggtgaagcg cgacgttacg cgctcactca ccgtcgcatg ctgcgtctct tcctttaata
     6601 ccggaatttg atcagcacgc gtgatatctt ctacagcgaa ggtctggcct gctattgcaa
     6661 gcaggccagc taacgcggta agcctaaaaa acatgttcat gcctggcccg gcctccgttt
     6721 cagaacacca ggtgttctgc gcgcacaatc aaagacatac ccgaattcag ctggacgcgg
     6781 acgccgtctt tggtgatttc taatacggtg gcatccatcg cgttttgacc cgctttcacc
     6841 ttcagggctt gtccgacagt cagagctgaa atgtcagaaa ccggggtgtg ctgttcttcg
     6901 cgaggtgctt ttactgtttt tggcgctttc tctaccggct tttgcgcacg aggtttacgt
     6961 tcagcgcctt ctttgcggcg tggcgtggtc gggcgtggct tgcgttcgcg gcgcggtgcg
     7021 tcttctttct caccagcagc tgcggcagct tcgcgttttt tcgcttgctg ttcagcacgc
     7081 tgtgcctgaa cacgcgcttt cgcttcttca agctgcttgc gagcatgctc gacatgttgc
     7141 tcgtccagct caccgcatgg gttgccgtca agatcaacac gcgttgcgcc ggatttaaca
     7201 ccgtaaagat aacgccagct cgaagtgtag agacgtaaag cggatcgcaa ttgcgttttg
     7261 ctcaggttca tttccccggc aacacgatcg accaaatcct gaaaaatacc gattttcagc
     7321 ggacgcgctt caccttccgc actgaaacag tggggaaaac gttcggccag aaacgcgatt
     7381 acttctttac tgctattcaa cttaggttga ttttccatga aatttcctga ttacaacgga
     7441 cgtagccaac aagcgcaggc atgaacaggc gtcattataa tgacgctatc agtaaatgct
     7501 acgttatccg ttgattatcc tgcgacgctc gcaaagaatt ttttgtaatc cgtcgttgca
     7561 agcacttttt caagctgtgc cacaagctga cgtaagcctt gctcgtcctc gtctgtaaag
     7621 cgaccgaaga cggtactatc gatgtcgaga acaccaataa tctgattttt caccaccagt
     7681 ggcagaacaa tttcagaatt actcgccgca tcacaggcaa tatgcccgtc aaacgcgtga
     7741 acatcctcga tacgctgcac ttgattgcgg gcaaccgcag tgccgcatac gccgcgccca
     7801 acgggtatcc ggacacaggc aattttgccc tgaaatggtc cgagcaccag tgtatcgtcc
     7861 tcaagcaaat aaaaacctgc ccagtttacg tcagtgagac gctcatataa caacgcactg
     7921 gtgttcgcaa gcgttgccag aaaactggtt tctcccgcca tcagcgcgtt aaagtcgcga
     7981 tttaaatccg cgtaaaattc tgctttgttc attatataat cacttggttg tcttacctgg
     8041 aactgccagc ctattaaaat aagcattaaa tgcgttaatg ctcaagatca ttcccatcat
     8101 gggttaagat taatgttaat tcttattaca tttggcacgt catggctctt aacacaccac
     8161 aaattacgcc gacaaagaag ataacagtga gggctatcgg cgaggaactg ccgcgtggtg
     8221 attaccaacg ttgcccgcaa tgtgacatgc tgtttagcct gcccgagata aattctcatc
     8281 aaagtgccta ttgtccgcgc tgtcaggcaa aaattcgtga cgggcgcgac tggtcgctaa
     8341 cgcgcctggc ggcaatggcc ttcaccatgc tgttgcttat gccgtttgcc tggggcgaac
     8401 cgctgttgca tatctggctg ttaggcattc gtattgacgc caacgttatg caaggcatct
     8461 ggcaaatgac caaacagggc gatgcgataa cgggggcgat ggtctttttc tgcgttatcg
     8521 gtgcccccct cattctggtg acctccatag cttatttatg gtttggtaac cgattgggaa
     8581 tgaatttacg cccggtactg ctgatgcttg agcggctgaa agagtgggtg atgttggata
     8641 tctacctggt cggcattggc gttgcttcta taaaggtaca ggattatgcc catatccagg
     8701 cgggggtcgg cttgttctct tttgtggcgt tggtgatttt aacgacggtg acgttgtcac
     8761 atcttaatgt cgaagaactg tgggagcgat tttatccgca gcgccccgct acgcgaaggg
     8821 acgagaaact ccgtgtctgt cttgggtgcc attttaccgg ctatcctgat cagcgtggtc
     8881 gctgcccgcg ttgccatatc ccgctactcc tgcgtcgccg tcatagtctg caaaaatgct
     8941 gggcggcgct gttagcgtca atcgttttgt tgttacctgc caacctgttg cctatctcta
     9001 tcatttatct gaatggtggt cggcaggaag atacgattct ttccggaatt atgtcgctgg
     9061 caagtagcaa cattgcagtt gcgggaatcg tgtttatcgc cagtattctg gtaccgttta
     9121 ctaaagtgat cgtcatgttc actttactgt tgagtattca ttttaaatgc cagcaaggtt
     9181 tacgcacacg cattctgtta ctgcggatgg tgacctggat tggtcgctgg tcgatgctcg
     9241 acctgtttgt catatcttta accatgtcgc tgattaatcg cgatcagatc ctcgctttta
     9301 ctatgggacc ggctgcgttt tatttcggcg cagcggtaat tttgactatt cttgctgtgg
     9361 aatggctgga cagccgctta ctttgggatg cacatgagtc aggaaacgcc cgcttcgacg
     9421 actgaagcgc agattaaaaa taaacgccgt atctcacctt tctggctgct gccgttcatc
     9481 gcgctaatga ttgctggttg gctgatttgg gacagttatc aggaccgggg caatactgtc
     9541 accatcgact ttatgtcggc ggatggtatt gttccaggcc gtacgcctgt tcgttatcag
     9601 ggcgttgaag ttggaacagt gcaggatatc agcctcagcg acgatcttcg taagattgaa
     9661 gtcaaggtca gcatcaagtc cgatatgaaa gatgcgctgc gcgaagagac acagttctgg
     9721 ttggtgacgc caaaggcctc gttggcaggt gtctccgggc tggacgccct cgtcggtggt
     9781 aattatatcg gcatgatgcc gggtaaaggt aaagagcagg atcactttgt cgcactcgac
     9841 acccaaccga aatatcggct ggacaatggc gatctgatga tccacctgca agcccccgat
     9901 ctcggttcac tgagcagtgg ttcattggtc tatttccgca agatcccggt gggtaaagtc
     9961 tacgactatg ccatcaatcc caacaagcaa ggcgtggtga ttgatgtcct gatcgagcgg
    10021 cgttttaccg atctggtgaa aaaaggtagc cgtttctgga acgtttccgg cgttgatgcc
    10081 aacgtcagta tcagtggcgc gaaggtgaaa ctggaaagtc tggcggcact ggttaacggt
    10141 gcgattgcct tcgattcacc tgaagagtcg aaacctgccg aagcggaaga tacctttggt
    10201 ctgtatgaag acctggccca tagccaacgt ggcgtaataa taaaactgga actgccaggc
    10261 ggtgccggat taaccgccga ctcgacgccg ttaatgtatc aggggctgga agtcggacag
    10321 ctgactaaac tggatttaaa tcctggtggt aaagtcactg gggaaatgac cgttgatccc
    10381 agcgtcgtca ccctgcttcg tgaaaatacc cgcatcgaat tacgtaatcc aaaattatcc
    10441 cttagcgatg ctaatctcag tgccctgctg accggcaaaa ccttcgaact ggtgcccggc
    10501 gatggcgagc cacgtaagga gttcgtggtt gtgccaggcg aaaaagccct gctgcaagag
    10561 ccggatgttc tgacactgac cctgacagca ccagaaagtt acggtattga tgctggtcag
    10621 ccgctcattc ttcacggcgt gcaggtaggc caggttatcg atcgtaaact caccagcaaa
    10681 ggcgtcacct ttaccgtcgc catcgagcct cagcatcgcg aactggtaaa aggcgatagc
    10741 aaatttgtcg tcaacagccg tgtcgacgtg aaggtggggc tggatggcgt tgagtttctc
    10801 ggtgccagcg cctcagaatg gatcaatggc ggaatacgta ttctgccggg cgataaaggc
    10861 gagatgaaag ccagctatcc actgtatgcc aatctggaaa aagcgctgga gaacagcctt
    10921 agcgatttac ccaccacaac cgtgagtttg agtgcagaga cgctgccgga tgtgcaggca
    10981 ggatcggtag tgctgtaccg taaatttgaa gttggtgaag ttattactgt gcgtccgcga
    11041 gctaacgcgt ttgatatcga tctgcatatt aaaccggagt atcgcaacct tctgaccagc
    11101 aacagcgtgt tctgggcaga aggtggggcg aaagttcagc tgaatggtag tggcctgacc
    11161 gtacaggcat ccccgctctc cagagcatta aagggggcta ttagcttcga taacctcagc
    11221 ggtgccagcg ccagtcagcg taaaggcgac aagcgtattc tgtatgcttc cgaaacagcg
    11281 gcccgtgcgg ttggcgggca aattacgctt cacgctttcg atgccggaaa actggcggtc
    11341 gggatgccaa ttcgctatct cggtattgat atcgggcaaa tccagacgct ggatctgatt
    11401 accgcgcgca atgaagtaca ggcaaaggcg gtgctctatc cggaatatgt ccagaccttt
    11461 gctcgcggtg gtacgcgctt ctcagtggtc acaccgcaaa tttcggcagc tggcgttgag
    11521 catcttgata ctatcctcca gccgtatatc aacgtcgaac caggccgggg caatcctcgc
    11581 cgcgactttg aattacaaga ggccaccatt actgattcgc gttacctgga tggcttaagc
    11641 attattgttg aagcgccgga agccggttcg ttaggtatcg gtacacctgt gctgttccgt
    11701 ggtctggaag taggtacggt taccggaatg acgctgggga cattgtcaga tcgcgtgatg
    11761 attgcgatgc gcatcagtaa acgctatcaa cacctggtgc gtaacaattc cgtcttctgg
    11821 ttggcatcgg gttacagtct ggactttggt ctgacgggcg gcgtagtgaa aaccggcacc
    11881 tttaaccagt ttatccgtgg cggcatcgcc ttcgccacgc ctccgggtac gccactggca
    11941 ccgaaagccc aggaaggcaa gcacttcctg ttgcaggaaa gtgaaccgaa agagtggcgt
    12001 gaatggggaa ctgcgcttcc caaataatgc ccactgctcc ggcgtgcctg cgccggagcg
    12061 tttatgctaa actgcacgcc tgtttttttg ccagtggtat atgctcgtgg cccaacacac
    12121 cgtttatttc ccggacgcct ttctgacaca aatgcgcgaa gcgatgcctt cgacgctctc
    12181 ttttgatgat tttcttgccg cctgtcagcg cccgttgcgc cgcagcattc gcgttaatac
    12241 gctgaaaacc tccgttgctg atttcctgca attaaccgct ccttatggct ggacgcttac
    12301 gccaattccg tggtgtgaag aaggtttctg gattgaacgc gacaatgaag atgcattgcc
    12361 gttgggtagt accgccgagc atttaagcgg cctgttttat attcaggaag ccagttcaat
    12421 gttgcctgtt gccgccttgt ttgctgacgg taatgcacca cagcgggtga tggatgtcgc
    12481 tgctgcacca ggttccaaaa cgacgcaaat tgccgcgcgg atgaataacg aaggggcaat
    12541 ccttgccaat gagttttccg ccagtcgggt aaaagtgtta catgccaata tcagccgctg
    12601 tggcatcagt aatgttgcgc tcacgcattt tgatggccgc gtatttggtg cggcagtgcc
    12661 agaaatgttc gatgccattt tgctggacgc tccctgctcc ggcgaaggcg tggtgcgtaa
    12721 agatcccgat gcgctaaaaa actggtcacc agaaagcaat caggaaatcg cagcgaccca
    12781 acgggagctg atcgacagcg cctttcatgc attacgtcct ggcggtacgc tggtttactc
    12841 gacctgtacc ttaaaccggg aagaaaacga agccgtttgc ctgtggctga aagagactta
    12901 ccccgacgca gtagagtttt taccgcttgg cgatctcttc cctggtgcaa acaaggcgct
    12961 gaccgaggaa ggctttttgc atgttttccc acaaatttac gactgcgaag gcttcttcgt
    13021 tgctcgtctg cgtaaaactc aggcgatccc cgtcttaccc gccccaaaat acaaagtggg
    13081 caatttcccg tttagcccag tgaaagatcg cgaagccggt caaattcgtc aggcggctgc
    13141 aagtgttggc ttaaactggg atgaaaacct gcgactctgg cagcgtgaca aagaactgtg
    13201 gttgttcccg gtgggcattg aagccctgat cggtaaagtc cgattttctc gcttggggat
    13261 taaacttgcc gaaacgcaca acaaaggtta tcgctggcag catgaggccg ttattgccct
    13321 tgcctccccc gacaatgtga acgcttttga actgacaccg caggaagcgg aggagtggta
    13381 tcgcgggcgc gatgtatacc cgcatgccgc gccagtggcg gatgatgtat tggttacttt
    13441 ccagcatcag ccgattggtt tagccaaacg gattggttca cgactgaaaa acagctaccc
    13501 gcgtgaactg gtgcgcgacg ggaaactttt taccggtaac gcctgacagc gcacaaaaaa
    13561 gcgcactttt tgactggcac attcgactgc ctcaactagg ctgaaaaatg gtgcgatcgg
    13621 actggtcgta ccacaaccgg cagctaaatg gagagcacga agatgaaaac cagtgtgcgc
    13681 ataggcgctt ttgaaatcga cgacggcgaa ttacacggcg aatcgccggg tgatcgaacg
    13741 ttaaccattc cttgtaaatc agaccccgat ttatgtatgc aactggatgc ctgggatgct
    13801 gaaaccagta tccctgccct gctaaatggc gaacactctg tcctttaccg tacccgttac
    13861 gatcaacaat ctgatgcctg gattatgcgt cttgcctgat ccaaaaagaa cccgtcggca
    13921 tggcgggtta tttgtccggg ttattccccc gttgtaaaat ctctcctaaa cttaacggta
    13981 cggcaccaca cttcggggat gaaatgttcg cgctggtact ttttgtttgc tacctggatg
    14041 gcggttgtga agatattgtt gtggatgtct acaacacgga acagcagtgt ctttattcta
    14101 tgagcgatca acggatccgc catggcggtt gttttccgat tgaggatttt atagatggtt
    14161 tctggcgacc tgcacaggag tacggtgatt tttaattatt gcaattgcac aagagtcagt
    14221 tctcccccaa agacagcacc ggtatcaata taatgcaggt tgccaatatc cacgcgatgg
    14281 cgcaaaggtg tatgaccaaa ccagaaatga tcagcacctg caattccctg ccctttttgg
    14341 cgttcaccta atcgcgagcg gctccacaag acctgatgca aatcgacgtc cttttgccat
    14401 tcataaacat catctggata atcggcatga gcaataacat gtttgccggt gcggctgtgt
    14461 acttcaagaa taaagggcaa atgctgacat ttttccagcg ccgttttcgc ttgtttctgt
    14521 tgattatctg ccagcgcaat aaaccagtcg ccgccattca tcaaccataa agacatctgc
    14581 cgggatgcca gcgcatccat cgccatctgt tcatgattgc ctcttaccgc acgaacccaa
    14641 tgttgttcca gtaactgcag gcaacgtaaa ctttgcggcc cacgatcgat aacgtctccc
    14701 actgagataa gtaaatctcg ccacggatca aaacgacaat gccataattt gcggcgcaat
    14761 tgctcaagac aaccgtgtat atcgcctgaa agccagatat gtcgccattg atgacccgca
    14821 attctctgat aaacgggcgc aggctgtttc atcaatattt tcctcccgcg ctaaagatca
    14881 cataatctta acaagaatgt taaaaaacgc tggactcaaa cagtagagtg tgtgttatgg
    14941 ttgactataa agtcagcgaa gggaatgctt ctggctttta acagataaaa agagaccgaa
    15001 cacgattcct gtattcggtc cagggaaatg gctcttggga gagagccgtg cgctaaaagt
    15061 tggcattaat gcaggcttag ttgccttgct ctttaagaat agatgacgac gccaggtttt
    15121 ccagtttgcg tgcaaaatgg tcaataaaaa gcgtggtggt catcagctta aatattaaaa
    15181 accgcccgtt ctggtgaaag aactgaggcg gttttttatt ggaaatcaaa aggctatttt
    15241 aggtaattaa cagagttttt cagctcgctc tataaacggt gccagactca ttttttcgcc
    15301 gggattgtta ggatcatcaa tctgaatcac cgaaatgggt tgggctttag tcttcccact
    15361 ggcaacttcc ttttgtgcga tatcgtttaa aggatactgc acgagagtac ttgggttaat
    15421 gacatacaaa gcattacccg gtcggcaagt cagcatcacc tcttcgcgat taaacgccca
    15481 tttgtcttta cctacttcaa aacggctgac ggtaatcacc tgcggtgccg ccagcgcagc
    15541 tgcagaactg gtgagtaaca gaaacgccag aatacttttt ttcatcattt tcgtaatcca
    15601 tcaaaaaggt tcgagagtcg caagcaggct gatgatcacc agcactaccg cacctatcgc
    15661 ccattcgagt ttagtcatcc agacaaacca gggagccgca cgatcttcat cctgcctcat
    15721 gcgcggtaca agaacataac gattagccag cgcgatgacc accataatca tcaccaggat
    15781 ggctttgagc aataagagtt ggccccagtg agtcgtaagc gtggggggaa atccggtaat
    15841 caacaatgca ttaagcacgc cgcttgccag tacgccgatc accgcaaaat gcccgcacca
    15901 ggaaaaacgc atcagcgcct gaatagcctg gtgtcgccaa cggcctttga tgagttgcat
    15961 acaccagagc accggcagta atcccccaaa ccacgccgcc gcacagatca ggtgaattgc
    16021 atgattagtc tgatggattt tcgccgttac cccttcattc agcgtcgcat gaccgactcc
    16081 cgccagcaga ataaattgcg cggtagtgag cataaatagc aaacgtggca tattctgcgg
    16141 ttgcataagg gcgacgatca atgttacgag ggcgagaaca atttgccata accagacgcc
    16201 accaaactgc gtttgcaaaa cagccagcca aatgtttggc gaaaatacat ctgaccatcc
    16261 cgttcccatc aacccgccct gaacggcgag cattgcagtg gcactgatca aactccagac
    16321 ggcagcgtgc tgttgtaaac gcagaaaacg cttcgtcagc aagcgacgaa tcgttaaggg
    16381 ggccagccag gcaccgtaca ttgcgaagcc aaaaaccagc atcagcgagg tgaaatggat
    16441 aaatcgcagc gcgatccagg taaacgccag catgatttat ttcacgctaa aggtgtaatg
    16501 tcctttcgtt ttatgcccat ccaccgaaac aacatgccag tcaacggtgt aggttccggg
    16561 tttcagcgaa tcggccagtg gaacaatcag ttgcttttgg tcctgctcat tacgcttcgc
    16621 cggtaatgtt ttaatatttt cgttttttgg ccccgtgatt tttgcgccac tgaatcctgt
    16681 ttcaacgcct tccgagaagt ttaaagtgat tgcctgcgga gctgctgtca cttgtgcatt
    16741 tgccgcagga tactgatgcg ttaaatgcgc atgtgcccag acggaaggtg tcaccaacga
    16801 agtggtcagg attgccagcg cgtagcgaag ggagcgtgca gttgaagcca tattatctat
    16861 tcctttttgt aataactttt ttacagagca taaccttgtc taatgtctga gtcgaggatc
    16921 atcaattccg gcttgccatc aaggctcact cttagtaact tttgcccgcg aatgatgagg
    16981 agattaagaa tgctgaagaa tctggctaaa ctggatcaaa cagaaatgga taaagtgaat
    17041 gtcgatttgg cggcggcagg ggtggcattt aaagaacgct acaatatgcc agtgatcgct
    17101 gaagcggttg aacgtgaaca gcctgaacat ttgcgcagct ggtttcgcga gcggcttatc
    17161 gcccaccgtt tggcttcggt caatctgtca cgtttacctt acgagcccaa acttaaataa
    17221 aacttataca tagttacact ttcttacata atgcctgcta aattatgagt attttctaaa
    17281 ccgcccccat aatttgcagt cattttgaaa aggaagtcat tatgtcgttc tggaaagttg
    17341 cagcagcgca atatgagcct cgtaaaacct cactcaccga acaggtagct catcatctgg
    17401 agtttgtgag ggccgccgcc aggcaacaat gtcagctgtt agtttttcca tcgctttctt
    17461 tactggggtg tgattattcg cgacgtgccc ttcctgcccc acccgatctc tcgctattag
    17521 acccgctttg ttatgccgca acgacctggc gaatgaccat cattgccggc cttcccgttg
    17581 aatataacga tcgctttatt cgtggaattg cggtattcgc accgtggcga aaaacgccag
    17641 ggatctacca tcagagttat ggtgcatgtc tgggccgtcg ttccagaacc atcacggtgg
    17701 tcgatgaaca accgcaaggt atggatatgg acccgacctg ttcactgttt acgacagggc
    17761 aatgtctggg agaacccgac ctgctggcgt cggcccgtcg cttacaattt ttttcacatc
    17821 agtactcgat tgctgtgctg atggcaaatg cccgtggtaa cagtgcacta tgggatgaac
    17881 atggtcgtct catcgttcgc gccgatcgtg gttcattatt gttagtcggt cagcgttcat
    17941 cacagggttg gcaaggcgat atcattccat tacgctaggc tttttcggcc tggagcatgc
    18001 catgttgcgc attatcgata cagaaacctg cggtttgcag ggagggatcg ttgagattgc
    18061 ctctgttgat gtcattgacg gaaaaatcgt caatcccatg agccacctgg tgcgtcccga
    18121 tcgtcctatt agtccacagg cgatggcgat tcatcgcatc accgaagcca tggtcgccga
    18181 taaaccgtgg attgaagatg tgatcccgca ctattacggt agtgaatggt atgtcgcgca
    18241 taacgccagc tttgaccgcc gcgtactgcc tgaaatgccc ggtgagtgga tttgcactat
    18301 gaaactggcc cgtcgtttgt ggccagggat caagtacagc aatatggcgt tatataaaac
    18361 acggaagctc aatgtacaga cgccgccggg cctgcatcat caccgcgcgt tgtatgactg
    18421 ttatatcacc gctgcgttgc ttatcgatat tatgaacacc tccggctgga cggcagaaca
    18481 gatggccgat atcaccggac gtccatcgtt gatgacgact ttcacctttg gcaaataccg
    18541 tggcaaagcg gtttccgacg ttgccgaacg cgatccgggc tatctgcgct ggttatttaa
    18601 taacctggac agcatgagcc cggagctgcg tttaacactg aaacattatc tggaaaatac
    18661 ttaatccgca ggcgtagcgg gtaatgttcc ctgcgccagc gcgaccagaa aagcatattc
    18721 catcgctacg ccttcgtacg atttaaagcg accagattta ccgccatggc ctgagtccat
    18781 gtcggtacag agcaataaaa gatggttatc ggttttcagc tcgcgcaatt tagcgaccca
    18841 ttttgccggt tcccaatatt gcacctgaga atcgtgtaaa ccggtcgtta ccagtaaatg
    18901 cggataagcc tgtgcggtga cgttgtcata cgggctgtag cttttcatat actcgtaata
    18961 ttgcggatcc tgcggattcc cccactcttc aaattcgccg gtggtaagag gaattgattc
    19021 atccagcatt gttgttacaa catcaacaaa cggcacctgg gcgataacgc cgtggaacaa
    19081 ttccgggcgt tgattaatcg caacgcccat caacataccc cccgcactcc cgcccatcgc
    19141 ataacagagc gaaggagagc catagcccag ttttaacaat gcatcgcagg catcaagata
    19201 atcattaaac gtatttttct tcttcagaaa tttaccgtcc tcgtaccatt gttgccccag
    19261 ctcaccgccg ccacgaacat ggacaatggc gtagacaaat ccacgatcca acaaactcaa
    19321 gcggctaaaa ctgaaatcgg catcaatact tgcgccgtaa gaaccgtagc catacaccag
    19381 cagcgggttg tgtcctttgc gaaaatgttt gcgatgatag accagcgaaa ccggaacttc
    19441 gacgccatca cgggcgacta tccacaggtg ttcactgcgg taattcgccg catcaaaacc
    19501 aggaacttcc gtttgtttta atacacgacg ctcaccggta tccatatcca gttcaaacaa
    19561 agtatctggt gtggtcatgg acgaataacc ataacgcaat cgcgcggttt caggttctgg
    19621 attgtaggca atccaggtca cataggccgg atcatcaaag gcaatgccaa tgacttcccg
    19681 ggtcttgcgg ttaatttgcc gcaaactggt taacccgcgc tgacgctctt caaccaccag
    19741 ccagtcggta aacagcgtaa acccttccag cataatgtta tcacgtggcg gaattaactc
    19801 ttcccactgt tgctcatcac gcatacgggt acggtataag ccaaagtttt taccgtggcg
    19861 gttggaacgc agataaaacc gatgctggta gtgatcaagg ctgtattcgt gatctttgcg
    19921 gcgcggcaga aaaacaaacg gctcggcatc ggctatttcc gcgtccagca ggcgaacttc
    19981 actggtggtg gcgctggcca gatgaatgac tacatagtgc ttcgaggtcg ttttatgcag
    20041 gctgacgtaa taggtatcgt ctttttcttc gtagatcagt ttatcctgcg atgctggcgt
    20101 accgatggcg tgacgccaga cctgataagg aagcagcgtc accggatgct tgcgaacata
    20161 gtagaaagtc caggaatcat ttgcccagac aaagctgggg tcaacgttat ccagcagttc
    20221 cggataccag ttacctgttt ccagattacg aaaacgaatg ccgtactggc gtcgggaaag
    20281 aaaatcttct gccagtgcca taatggtgtt atcgggcgta atcgccattc cgcccatcga
    20341 ataaaactca ctatgagccg cgcgcttgtt ggcatcgagc aatgtttccc actcatccca
    20401 ctcttcgctg aacgccgatt gacgctggta gatagcatat tcacagcctg gttcataaat
    20461 atgccgatag cggtagccat tttttatgta gggcgcagaa acttctcttt gcggaatgcg
    20521 gtcgatgatt tcctttaaga tgcgatcctg caaggcttgt tgcgaggcca tcacccgatg
    20581 accgtaacta ttttcttgtt gcagatagtc caggacttcc ggctgagaac gcgtatcgtc
    20641 ccgcagccag tagtaattat cgatgcgcgt atcgccatga agcgtcatgg cgtggggaat
    20701 gcgggcggct tttggtagca tgttattgtt ctttctggtt gaaacatctt ataagggtgg
    20761 caaaactcac cggggatgca agcgaaacag ggtagtcatt gcttagatga tgacaggtaa
    20821 tggcgcggat atcgactgtt atgcagacag agaaaatcag cctgttcaaa tggctgtgcg
    20881 gttctggata acccgaaata gtcaacttca ggctatccag agagcggaat tactccgcca
    20941 aagtacgttt ttgctgttcg agatcgcgtt caatgccttc acgaacgtcc tgggggattt
    21001 tcagcgcatc acccagtgca ttcaggtaac tgcgttccat aaaatggtca atatcaatag
    21061 ccgcgcagct caggaaatag atttccagcg cctcttcttc attgcggacc ccggtagcca
    21121 ggcgttgtgg atccagcggt tgttcgattg cctgctcaat gagtacacgc cccttctctt
    21181 ccacaccggc ttcacgcaat tgcaggtcga ttgccgcacg ttctttggca tcaatatgac
    21241 catcactttt agcggcaaag accagcgcaa ggatcaaacg ttccgtacgc tcatccagcg
    21301 gcgtactttg cgcgccaaac tgcggttcgt cctgatgcgc cgcgcgaatt ttatctttgt
    21361 atttattcca cagcaccgta cccgctaccg ctccgccgcc aaccagtaac gcgtttgtgc
    21421 catatttcgt aagaagttta cgtgctgatt tatttgcgac cagcagccca gccagtccgc
    21481 ctaatgcgcc aggcactaaa agtttgccca atccctgatc cgcagacgag gaggtagaag
    21541 aacggctttg cccaagcagg gattgcagtt gatttaacca gttagccata tttgctcctc
    21601 aataaccatt tttagtgcct gtagcatagc ggatgaggat gtcagaaaat gtatatcgag
    21661 acaaaagatg cgcaaataag cggggcggta ggccgttatt caaagaaatt cgcgccaggt
    21721 aaggtgttca ctgtatataa ggtgataagg gtattttagg tgaaagtagt ttgacatttt
    21781 gagtggaact gtttgatgct gattgcccgg ttcgacgcta ctgcgtcttc tcaggcctac
    21841 gattgtgttg cgttgtaggg cggacaaggc acccgcgccg catccgccaa cggtcaatcg
    21901 aattatcaga agccattaac gccgctgata ttccgccatt cccgctttgc agtccacgct
    21961 gacctggtaa tgaatatcgg cacttttacc acgcacggtt agcggtactg accatttatc
    22021 atctttcccc tgaatgtcct gcaaactgac ccatgccacg ggatcggcct gaccgacaat
    22081 tttttgatca tcagcccagc gcgccacgcg attttgttgg taatcacgtt ttacgctcgc
    22141 ggcaattccg gcagcatcca gaccttcaca ctttgggaaa gtgaccgact tgctggtttc
    22201 attattggca gcgaaaactg atgcgcaggc agaaaccaac aacagcccta aaaacgcccc
    22261 tctttttttc atgtttttct ccatagcaca atgattcagg agaaagcatg gtacaaattg
    22321 tcaggagcgc aagttgcttc aggccgcgtg tgaggcatct tcctcttcgg attcagcacc
    22381 gacgacctgt ggggacggta atttgccggt tttcagaatg gtgctcagca catctttttg
    22441 ttctgccagc catagcgaaa gggcttcacg ttgctcgtct tccatttgca ctggagaatt
    22501 tgtcagccag gtgtcaagca gatcggccgt atcaagcatc ttgtcataag catcggcttc
    22561 ctttttgctg gtaaacgaca ttttctcttc gccctcacga atgactacgt atttaacttc
    22621 aaccgccatt tgcagcctct cataataact gtggttttat acagtatatt tcttttcagt
    22681 tgggaaatca acatcagcaa taaagacaca cgcaaacgtt ttcgtttata ctgcgcgcgg
    22741 aattaatcag gggatattcg ttatgacgtt attaggcact gcgctgcgtc cggcagcaac
    22801 tcgcgtgatg ttattaggct ccggtgaact gggtaaagaa gtggcaatcg agtgtcagcg
    22861 tctcggcgta gaggtgattg ccgtcgatcg ctatgccgac gcaccagcca tgcatgtcgc
    22921 gcatcgctcc catgtcatta atatgcttga tggtgatgca ttacgccgtg tggttgaact
    22981 ggaaaaacca cattatatcg tgccggagat cgaagctatt gccaccgata tgctgatcca
    23041 acttgaagag gaaggactga atgttgtccc ctgcgctcgc gcaacgaaat taacgatgaa
    23101 tcgcgagggt atccgtcgcc tggcggcaga agagctgcag ctgcccactt ccacttatcg
    23161 ttttgccgat agcgaaaacc ttttccgcga agcggttgcc gccattggct acccctgtat
    23221 tgttaaaccg gtgatgagtt cttccggtaa agggcagacg tttattcgtt ctgcagagca
    23281 acttgctcat gcatgggagt acgctcagca aggtggtcgc gccggagcgg gccgcgtaat
    23341 tgttgaaggc gtcgttaagt ttgacttcga aattaccctg ctaaccgtca gtgcggtgga
    23401 tggcgtccat ttctgtgcac cggtaggtca tcgccaggaa gatggcgact atcgtgaatc
    23461 ctggcaacca cagcaaatga gcccgcttgc ccttgaacgt gcgcaggaga ttgcccgtaa
    23521 agtggtgctg gcacttggcg gttatgggct gtttggtgtc gagctgtttg tctgtggtga
    23581 tgaggtgatt ttcagtgaag tctcccctcg cccgcatgac accgggatgg tgacgctaat
    23641 ttctcaggat ctctcggagt ttgccctgca tgtacgtgcc ttcctcggac ttccggttgg
    23701 cgggatccgc cagtatggtc ctgctgcttc tgccgttatc ctgccgcaac tgaccagtca
    23761 gaatgtcacg tttgataatg tgcagaatgc cgtaggcgca gatttgcaga ttcgtttatt
    23821 tggtaagccg gaaattgatg gcagccgtcg tctgggggta gcactggcta ctgcagagag
    23881 tgttgttgac gccattgaac gcgcgaagca cgccgccgga caggtaaaag tacagggtta
    23941 aacccggcaa aaaaacgcta caaaaatgcc cgatcctcga tcgggcattt tgacttttac
    24001 agcttagcgc cttctacagc ttcacgcgcc agcttagtaa tgcggtcgta atcgcccgct
    24061 tccagcgcat ctgccggaac cagccaggaa ccaccgatgc acagcacgct tttcagcgcc
    24121 aggtagtcac ggtagttagc cggagaaata ccacctgtcg ggcagaaacg gacctgggag
    24181 aacggacccg cgatcgcctg cagggctttc acaccgccgt tagcttcagc cgggaagaat
    24241 ttgaactctt tcaaaccgta gtccataccc agcatcagtt cggaaacagt gctgatcccc
    24301 ggaatcagag gaatagtccc ttcggtagca gctttcagca gcggctcggt cagacccggg
    24361 ctaattgcaa actgtgcacc tgcttcagtg acttctgcca gctgctgtgg attcagcacc
    24421 gtaccggcac ccacaatcgc ttcaggcact tctttggcga tagcacggat agcgtcaact
    24481 gcgcactcgg tacgcagagt cacttccaga acgcgcaccc caccagcaac caacgctttt
    24541 gctatcggca ccgcgtgttc cagttttttt accacgataa ccggtacaac cgggccggtg
    24601 gtcaggattg attctgcact tgttttccag tttttcatca gagttttctc tcgcctgatt
    24661 acaaatttgt cgtcttaaaa agtgatacag gttgcgccct gttcggcacc ggacagtttt
    24721 tcacgcaagg cgctgaataa ttcacgtcct gttcccacgc gtgacgcgct caggtcagga
    24781 atgtgcggtt cgcgagcagc cagttccgct tcgtctacca gcagcgtcag ttcgcctgtc
    24841 tgtccattca cacgaatgat gtccccgtcg cgcacttttg ccagcagccc gccatcgtag
    24901 gcctctggtg ttacgtggat agctgacggc actttacctg aagcgccgga gagtcgtcca
    24961 tcggtaacta acgcaatttt gaaacaccgg tccaataata caccaagtgg cggcatgagt
    25021 ttatgtaatt ctggcattcc gttcgctttt ggcccctgat gacggacaac aacgacacaa
    25081 tcgcggtcca gtaaacccgc ttcaaaggcc ggcataacgt catgctggct ttcaaaaaca
    25141 accgctggcg cttcaatcac ctggttctct accggcacgg cagaggtttt cataaccgct
    25201 cgccccaggt taccgcttaa cacttttgtc ccaccatgat gagagaaagg ttgttcgaag
    25261 gacgcgatca cattgttgtc gagtgatttt tctgcccctt cccgccagtc cagttcacca
    25321 ttattcagcc atggttcaag ggtataacga gacagaccaa agcctgccac cgtattgaca
    25381 tcttcatgca gcaggcctgc tttgagcagt tcacgtacca gaaccggtac gccacctgcc
    25441 gcctggaagt ggttaatatc ggccggaccg ttcgggtaga gacgtgccat cagcggtaca
    25501 acatcagaaa ggtcagagaa gtcatcccag ttaatctgaa taccggctgc gcgcgccatc
    25561 gccactaggt gcatggtgtg gttagtggaa ccaccggtcg ccagcagtgc aacgataccg
    25621 ttcaccacca ctttctcatc gatcatctta ccgatcggca tccattcatt accattaccg
    25681 gtcatgcgcg taacctggcg cgcagctgca gcggtcaaag catcgcgcag cggagaatcc
    25741 ggatgaacaa aagaagagcc tggcaactgc atccccataa actccaccac catctggttg
    25801 gtgttggcag taccgtagaa agtacatgtt cccggcgcat gataagacgc ggcttctgac
    25861 tccagtaatg ccatgcggtc cactttacct tcggcataaa gctggcgaat acgcactttt
    25921 tctttatttg gcaaaccgct tgccatcggt ccagacggca caaacaccgc aggcaaatga
    25981 ccaaacgaca gggctgccat ggtcagacct gggacaatct tgtcgcacac accgagaaac
    26041 agagcaccat caaacatgtt atgggacagc cccaccgccg cagacatcgc aatcacttcg
    26101 cggcttaaca gcgacaattc cattccatcc tgcccctggg tgacaccatc acacatcgcc
    26161 ggaacaccgc ccgcaacctg accaaccgca ttcgcttcat gcagggcttt acgaatgatt
    26221 tctggatagt gttcataagg ctggtgagcg gagagcatgt cgttatagga ggtgatgatg
    26281 gcgatattgt tacgcaacat gcttttcaaa gaggctttgt cttctggctg gcaggcagcg
    26341 aaaccgtgtg ccaggttacc gcatgccaac tgcgaacgat gaacggtcga agttttcgct
    26401 tgttctatcc gggcgaggta agcagagcga gtctcgcgcg aacgttcaat gattcgattt
    26461 gttacgcgta acaattgtgg gttcataaag gctcctgaaa ttgagttgtc agagcaggat
    26521 gattcacaac gcgtttcata catggaaatt atgattgaaa cgcctgtaac cggagctcat
    26581 agggcaaaaa cgtttcagtc agtgtaataa aaaaagcctc gtgggtgaat ccgcacgagg
    26641 cctgaaagtg taaaaattgt tctacaatct gtgcaagatc atgttaccgg taaaataacc
    26701 ataaaggatg agcgcagata ttactcaaac tcattccagg aacgaccatc acgggtaatc
    26761 atcgccactg aggcaacggg tccccaggtt ccggcctgat acggtttcgg cgcatcattg
    26821 tccatcgccc acgcctcagt aatggagtct acccatttcc aggcttcttc cacttcgtcg
    26881 cgacgtacaa acagtgcctg aataccacgc atggtttcca gcagcaaacg ttcataggca
    26941 tccgccagat gcgtctgatt aaaggtttct gaatagctca gatccagctt ggtgatttgc
    27001 aggttatgtt tgtggtcaag gccaggaact ttattcagta cctggatatc cacgccttca
    27061 tcaggttgca gacggatagt cagtttattt tgcggtagat cctgccacga ctctttaaac
    27121 agattcagtt caggtgtttt gaaatagacc acgacttcag aacatttggt cggcagacgt
    27181 ttaccagtac gcaggtagaa tggcacaccg gcccagcgcc agttatcaat gtcgacgcgg
    27241 atcgccacga aggtttctgt attgctgctc ttgttcgcgc cctcttcttc cagatagccc
    27301 ggcacttttt tgccctgagc gaagcccgca gtatattgcc cgcgtacggt tttttcgcgc
    27361 acattggagc ggtcgatgcg gcgcagagac ttcagtactt tcactttttc atcgcggatg
    27421 ctgtctgcgc tcaggtcaga cggcggagac atcgcaatca tgcaaagaat ttgcagcagg
    27481 tggttctgga tcatgtcgcg catctgaccg gctttatcaa aatagcccca gcgcccttcg
    27541 atccccactt cttctgccac ggtaatctca acatgatcaa tggtgcgatt gtcccagttg
    27601 ttcacaaaca gagagttagc aaaacgcagc gccaacaggt tcagcactgt ttctttacca
    27661 agatagtggt cgatacggta aacctggcac tcctcgaagt attcgccaac ctgatcgttg
    27721 atttcctgcg aggtcgccag cgacgtcccc agcggttttt ccatgactac gcgtgccggt
    27781 ttagcattca gttttgcctc accaagccct ttgcaaattg cgccaaaagt gctgggcggc
    27841 atggcaaagt agttaatggt gatacgattt ttttgatcca gcatcgcgcc gagacggctg
    27901 aatgcagcag tgtcattgac atcaagatta caaaaatcca gacgtgcact cagggtgtcc
    27961 cataaacctt catcaatggt ttctttcatg aaagtttcga gcgcctcgcg gacaactttg
    28021 gtataagccg ctttatccca gtcagcacgc cctacgccga taatccgggt gtccgggttg
    28081 agctgaccgg ctttttccag ttgatacagg gaaggcagca atttacgacg cgcaaggtcg
    28141 cctttcgcgc cgaaaatgac caggtcacag gcctgggctg tttgcgttac cgccatgtca
    28201 ttctccttaa gttaactaac ccggtactta agccagggta tacttgtaat tttcttacgg
    28261 tgcactgtac tgcttttacg agcttgcgaa aactgtaaac gcttatccac ccgtgcgatt
    28321 acggtaaaag cgcgcaaagt gcggcaaaac tgataaaaaa atcatcgttt tccattgggt
    28381 aaaaatctga cactgatcat gttatgaaaa aaaataacaa cttttttatc tgcttttgtc
    28441 attaacacag cacacaggcg taatatctga caaaactgca tttcgatttc tttcagagcg
    28501 gaaatcgtca ttacccgtga gtctctttac atcatgaata tgctggaaaa aatccagtct
    28561 cagctggaac atttgagcaa atctgagcgc aaagttgccg aggtcattct ggcttcgccc
    28621 gataacgcga tccattcgag tattgctgct ctggcgctgg aagccaatgt tagcgaaccg
    28681 acggtgaatc gtttctgtcg cagcatggac acacgcggtt ttcctgattt taaacttcat
    28741 ctggcacaaa gtctggcgaa tggcactccc tatgttaatc gcaacgtcaa tgaagatgac
    28801 agcgttgaat catacacggg gaaaatattt gagtccgcaa tggcaacgct cgatcatgtc
    28861 cgtcattcac tggataaatc tgccatcaac cgcgccgtcg acttgctcac tcaggcaaaa
    28921 aaaatcgcct ttttcggatt aggttcttca gccgccgttg cccacgatgc gatgaataag
    28981 ttctttcgtt ttaatgttcc ggtggtgtac tccgatgata tcgtgctgca acgcatgagt
    29041 tgtatgaatt gtagcgacgg agacgtggtg gtgctgattt ctcacacggg aagaacaaaa
    29101 aatctggtcg agctggcgca gctggcacgc gaaaacgacg ctatggtaat tgccctcacc
    29161 tctgcgggta ccccactcgc ccgggaagca acgctggcaa ttaccctcga cgtaccggaa
    29221 gatactgaca tttatatgcc catggtttct cgacttgcac agctgaccgt gatagatgtg
    29281 ctggcgacag gatttacttt gcggcgcggt acaaaattca gagataactt gaagcgggtc
    29341 aaggaagcgc tgaaggaatc gcgttttgat aagcagttac ttaatttaag tgacgatcgc
    29401 taaaaacgac tgtcactgtc ctaatcttat acgacatccg aatgagatta atttatcgcc
    29461 atcacggcgt tatttcattc ggatttcatg ttcaagcaac acctggttgt ttcagtcaac
    29521 ggagtattac atgtccagaa ggcttcgcag aactaaaatc gttaccacgt taggcccggc
    29581 aacagatcgc gataataacc ttgaaaaagt tatcgcggcg ggtgccaacg ttgtacgtat
    29641 gaatttttct cacggctcgc ctgaagatca caaaatgcgc gcggataaag ttcgtgagat
    29701 tgccgcaaaa ctggggcgtc atgtggctat tctgggtgac ctccaggggc ccaaaatccg
    29761 tgtatccacc tttaaagaag gcaaagtttt cctcaatatt ggggataaat tcctgctcga
    29821 cgccaacctg ggtaaaggtg aaggcgacaa agaaaaagtc ggtatcgact acaaaggcct
    29881 gcctgctgac gttgtgcctg gtgacatcct gctgctggac gatggtcgcg tccagttaaa
    29941 agtactggaa gtccagggca tgaaagtgtt caccgaagtg accgtcggtg gtcccctctc
    30001 caacaataaa ggtatcaaca aacttggcgg cggtttgtcg gctgaagcgc tgaccgaaaa
    30061 agacaaagca gacattaaga ctgcggcgtt gattggcgta gattacctgg ctgtctcctt
    30121 cccacgctgc ggcgaagatc tgaactatgc ccgtcgtctg gcacgcgatg caggatgtga
    30181 tgcgaaaatt gttgccaagg ttgaacgtgc ggaagccgtt tgcagccagg aggcaatgga
    30241 tgacatcatc ctcgcctctg acgtggtaat ggttgctcgc ggcgacctcg gtgtggaaat
    30301 tggcgatccg gaactggtcg gcattcagaa agcgttgatc cgtcgtgcac gtcagctaaa
    30361 ccgcgcggta atcacggcga cccagatgat ggaatcaatg attactaacc cgatgccgac
    30421 gcgtgcagaa gtcatggacg tagcaaacgc cgttctggat ggtactgacg ctgtgatgct
    30481 gtcggcagaa actgctgctg gtcaataccc gtcagaaact gttgcagcca tggcgcgcgt
    30541 ttgcctgggg gcggaaaaaa tcccgagcat caacgtttct aaacaccgtc tggacgttca
    30601 gttcgacaat gtggaagaag ccattgccat gtcagcaatg tacgcggcta accacctgaa
    30661 aggcgttacg gcgatcatca ccatgaccga atcgggtcgt accgcgctga tgacctcccg
    30721 tatcagctct ggtctgccaa ttttcgccat gtcacgacat gaacgtacgc tgaacctgac
    30781 tgctctctat cgcggcgtta cgccggtgca ctttgatagc gctaatgacg gcgtagcagc
    30841 tgccagcgaa gcggttaatc tgctgcgtga taaaggttac ttgatgtctg gtgacctggt
    30901 gattgtcacc cagggcgacg tgatgagtac cgtgggttct actaatacca cgcgtatttt
    30961 aacggtagag taagtacgtt gccggatgcg gcgaaaacgc ctcatccggc ctacagttca
    31021 atgataattc aacagatttc gaatcttctg aagcaaactt gaacttatca tcagtcgaag
    31081 gcctctcctc gcgagaggca ttttttattt gatgggataa agatctttgc gcttatacgg
    31141 ttggatttcg cccggtttgc gagttttcag caattttaat atccaggtgt attgttctgg
    31201 tcgcggacca acaaaaatct cgacttcttc attcatccgc cgcgcaatcg tatgatcatc
    31261 cgcctctaac agatcatcca tcggtgggcg cacctgaatc gtcagacgat gcgtcttgcc
    31321 atcataaatc ggaaacagcg gtacaacgcg cgcacggcac actttcatca aacgaccaat
    31381 cgcgggcaac gtcgctttat aggtggcaaa gaaatcaaca aattcgctgt gttctgggcc
    31441 atgatcctga tcgggtaaat aatatcccca gtaaccctga cgtaccgact ggatgaatgg
    31501 tttaatacca tcatttctcg catgcagacg accaccaaag cgacggcgca ccgtgttcca
    31561 gacataatca aaaaccgggt tgccctgatt atggaacatc gctgccattt tctgcccttg
    31621 cgaggccatc agcatggcag gaatatcgac ggcccaaccg tgcggcacca gaaaaatcac
    31681 tttctcgtta ttacgccgca tctcttcgat gatctccagc ccttgccagt caacgcgcgg
    31741 ctgaattttc tccggcccgc gtattgccaa ctcagccatc attaccatcg cttgcggcgc
    31801 ggtggcaaac atctcatcta caatcgcttc gcgttcagct tcactacgtt ctggaaagca
    31861 gagcgacaga ttgattaacg cacgacggcg tgagcttttt cccagtcgtc cggcaaaacg
    31921 tcccagccgt gccagaatgg gatcacggaa ctttggcggc gttaaagcga tacccgccat
    31981 cgctgctacg cccagccatg ctccccagta gcgcgggtgg cgaaaggatt tatcaaactc
    32041 aggaatgtat tcgctattat tttttttcgt ttccatgctt ttccagtttc ggataaggca
    32101 aaaatcaatc tggtgatagt gtagcggcgc aacttgcccc gcaccaaata aaaaagccgg
    32161 tactgactgc gtaccggctg cgaatggatg ttaattaatc aaaccgtagc tgcggcacaa
    32221 tctctttggc ctgtgccagg aattcgcgac gatcggagcc ggtcagccct tcggtacgcg
    32281 gcagttttgc cgtcagcggg tttacggcct gctggtttat ccatacttca tagtgcagat
    32341 gcggcccggt tgaacgtccg gtattaccgg aaagcgcgat acggtcgcca cgtttcacct
    32401 tctgtcccgg tttcaccagg atcttgcgca agtgcatata acgcgtggtg tagctgcgac
    32461 catgacgaat agccacataa taacctgctg cgccactacg tttggcaacc accacttcac
    32521 cgtcacccac tgaaagcact ggcgtacctt gtggcatggc aaaatcaaca cctctgtgtg
    32581 gcgcaacgcg accggtcacc ggattagtac gacgcgggtt aaagttagat gagatacgga
    32641 actgtttcgc cgtcgggaat cgcaagaatc ctttcgccag accagtaccg ttacgatcat
    32701 agaatttgcc atcttcagcg cggattgcat aataatcttt accttctgaa cgcaaacgta
    32761 cgcccagcag ctggctttgc tcacgtttac catcaagcat ttctcgtgac attaacaccg
    32821 caaattcatc gccttttttc agtttgcgga aatccatttg ccactgcatg gctttaatca
    32881 ctgcgctcac ttcggcgctg gttaaaccgg cgtttctggc gctggcaaca aagcttcccc
    32941 cgacggtacc tttcagcaga ttgttgaccc actctccttg ctgcatttcg ctggtcattt
    33001 taaaaccgtt agcggcagta cggtcatagg ttcgggtttc acgacgagac acttcccagg
    33061 tgaggcgctg cagttcgccg tccgcggtta atgtccagga gagttgttga ccgattttca
    33121 ggttacgcaa ttctttgtcg gcagcagcca gttgggtgat atcacccata tcaataccat
    33181 actgattgag aatgctgctt agcgtatcgc cagtggaaac aacatattca tgcacgcccg
    33241 cttcaccggc gattttgtca tccagttcgt cctggggaat ggcttcatct tcttgtgcag
    33301 cttgatcaat cggctcactg gcttcaggta agagcgaacg aatttcgttc tgttccagct
    33361 caatggtttt gacaattggc gtggcatcac ggtgataaac atagggccgc cagacagcga
    33421 cggccagagt aagaacggtg agcgacccca acataacgcg gtgtggtcgc ggtaaattat
    33481 taaacgccag ggcgacagag cgggctatct gttgcacgta atcacttcct cattaatctc
    33541 ctttcaggca gctcgcatac tggttggcta attgattcag gaattctgaa tagcttgttt
    33601 tacccagttt gatattcgtc cccaggggat ccaacgttcc catacgaacg gatgtccctc
    33661 gtgcgacgct ctcaacgacc gctggcctga actgtggctc agcaaaaacg caggttgctt
    33721 tttgctcaac caactgtgtt cttatttcat gtaaacgctg cgcgccaggt tgaatctcag
    33781 ggttaacggt aaaatgacca agcggtgtca gtccgaactg tttttcgaag tagccgtaag
    33841 catcgtgaaa aacgaaataa cctttcccct tgagcggcgc gagctcgtta ccaacctgcg
    33901 tttcggttga ggctaattgt gcctcaaaat ccttcaggtt ggcgtcaagt ttggctcgac
    33961 tttgcggcat aagttccact aattttccat ggattgcaac cgctgtagcc cgcgctatct
    34021 ctggggaaag ccaaagatgc atgttgaaat cgccgtgatg gtgatcttcg tcactttttt
    34081 ccgcgtgatc gtgatcatca tcatcgtcgt gaatactttt catcagcagc ggtttcacat
    34141 cttctagctg cgcaatcgtt acctgtttcg cttctggtaa tttacttacc ggtttttgca
    34201 tgaacgcttc catctccggg ccaacccaaa cgactaagtc cgcgttctgt aagcgtttta
    34261 catccgatgg acgcagtgaa taatcatgtt ctgaagcgcc gtcaggcagt aaaacctgcg
    34321 tttctgttac cccatcagca atggcagaag cgatgaaccc aacgggttta agcgaagcga
    34381 caacggcggc atctgcggcc tgtgttgcac cgccccagag agcggcggat aatgctgcga
    34441 aaagaagcgt ttttttatgt aacataatgc gaccaatcat cgtaatgaat atgagaagtg
    34501 tgatattata acatttcatg actactgcaa gactaaaatt aacatgacaa gtctggtttc
    34561 cctggaaaat gtctcggttt cttttggcca acgccgcgtc ctctctgatg tgtcgctgga
    34621 acttaaacct ggaaaaattt tgactttact tgggccaaac ggcgcaggta agtcgacact
    34681 ggtacgggta gtgctcggac tggtaacacc cgatgaaggg gttatcaagc gcaacggaaa
    34741 actgcgcatc ggctatgtac cgcagaagct gtatctcgac accacgttgc cactgaccgt
    34801 aaaccgtttt ttacgcttac gccctggcac acataaagaa gatattttgc ctgcactgaa
    34861 acgtgtccag gccgggcatc tgattaacgc accgatgcaa aagctctcgg gtggcgaaac
    34921 gcagcgtgta ctgttagcgc gagcattgtt aaatcgaccg caattattag tgctggatga
    34981 acccactcag ggcgtggatg tgaatggtca ggtggcgtta tatgacctta ttgaccaact
    35041 gcgtcgtgaa ctggattgtg gcgttttaat ggtatctcac gatctgcatc tggtaatggc
    35101 aaaaaccgat gaagtgcttt gcctgaatca ccacatttgt tgttccggca caccggaagt
    35161 tgtttccctg catccggagt ttatttctat gtttggtcct cgtggtgctg aacaactggg
    35221 tatctatcgc catcatcata atcatcgtca cgatttacag ggacgaattg ttttgcgtcg
    35281 gggaaatgat cgctcatgat tgaattatta tttcccggtt ggttagccgg gatcatgctc
    35341 gcctgtgccg cgggtccgct gggttcgttt gtagtctggc gtcgtatgtc ttatttcggt
    35401 gatacgctgg ctcatgcctc attacttggc gtcgcgtttg gtttgttgct ggacgtgaat
    35461 ccattctatg cggtgattgc agttacgctg ctgctggcgg gcggtctggt atggctcgag
    35521 aagcgtccac agctggcgat cgacacgtta ttagggatta tggcgcacag tgccctgtcg
    35581 ctgggcctgg tggtcgttag tctgatgtct aatattcgtg ttgatttgat ggcttacctg
    35641 ttcggtgatt tactggcagt gacgccagaa gatctcatct ctattgcgat tggcgtggtc
    35701 atcgtggtgg ctattttgtt ctggcaatgg cgcaatttgc tgtcgatgac gattagcccg
    35761 gatctggcgt ttgttgatgg tgtgaaatta cagcgcgtga aattgttgtt gatgctggtg
    35821 acggcattga cgattggtgt agcgatgaaa ttcgtcggcg cgttgattat tacttcactg
    35881 ctgattattc ctgctgctac tgcacgtcgc tttgcccgca cgccggaaca gatggctggt
    35941 gtcgctgttt tggtggggat ggtggcagtg actggcggtt taaccttttc cgcattttac
    36001 gatacacctg caggcccgtc ggtggtgcta tgcgcggcac tgttatttat tatcagtatg
    36061 atgaaaaaac aggccagcta atctttcgct gaacatattt gtcggatgcg gcgcgagcgc
    36121 cttatccgac cttgtattat ccctccagtg cagagaaaat cggtcagttt tctctgcctg
    36181 cagtccgcat gccttatccg acctacggtt cgctatctct ggtaggcctg ataagacgaa
    36241 c
//
LOCUS       DAFGPF010000045        35813 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFGPF010000045 DAFGPF010000000
VERSION     DAFGPF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35813
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.045"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            363..1187
                     /gene="gadX"
                     /locus_tag="LSX49_002429"
     CDS             363..1187
                     /gene="gadX"
                     /locus_tag="LSX49_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HBL7168830.1"
                     /translation="MQPLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIQV
                     DKCVENFVLVSRDTLSLFLPMLKEEALKLHVHKKVPSLLVHHCTRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDTQFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEGTSYSQLLTECRMQRALQLIVIYGVSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQELPNCGSAASMAAQGIFYGTDRSAEGIRL"
     gene            1556..2284
                     /gene="gadW"
                     /locus_tag="LSX49_002430"
     CDS             1556..2284
                     /gene="gadW"
                     /locus_tag="LSX49_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HBL7168831.1"
                     /translation="MAHVCSVILVRRSFDIHHEQQKISLHNESILLLDKNLADDFAFC
                     SLDTRRLDIEELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPIQLVTAIFDSFNDPR
                     VNSPILSKMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFSQHSPGTFS"
     gene            complement(2647..5760)
                     /gene="mdtF"
                     /locus_tag="LSX49_002431"
     CDS             complement(2647..5760)
                     /gene="mdtF"
                     /locus_tag="LSX49_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump RND permease MdtF"
                     /protein_id="HBL7168832.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIK
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKNNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELDTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPNQVIGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPVEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(5785..6942)
                     /gene="mdtE"
                     /locus_tag="LSX49_002432"
     CDS             complement(5785..6942)
                     /gene="mdtE"
                     /locus_tag="LSX49_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HBL7168833.1"
                     /translation="MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPG
                     SVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELN
                     SAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
                     EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQD
                     FLRMKEEVASGQIKQVQGSTPVQLNLENGKRYGQTGTLKFSDPTVDETTGSVTLRAIF
                     PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIE
                     ASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            7002..7331
                     /locus_tag="LSX49_002433"
     CDS             7002..7331
                     /locus_tag="LSX49_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168834.1"
                     /translation="MRDLQTSGIVGLSASKMGCKHSDRHGEVNDKKNVAVLPTVSASI
                     RATKGSTGGYTYQGNKVVFVSPSIITGGIEISICIPRHASHQFQLLMSLLKIRCDTQG
                     DDVAHTS"
     gene            complement(7281..7808)
                     /gene="gadE"
                     /locus_tag="LSX49_002434"
     CDS             complement(7281..7808)
                     /gene="gadE"
                     /locus_tag="LSX49_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HBL7168835.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
                     RRMSDIVTLGITSYF"
     gene            complement(8607..9179)
                     /gene="hdeD"
                     /locus_tag="LSX49_002435"
     CDS             complement(8607..9179)
                     /gene="hdeD"
                     /locus_tag="LSX49_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HBL7168836.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKKQ"
     gene            9434..9766
                     /gene="hdeA"
                     /locus_tag="LSX49_002436"
     CDS             9434..9766
                     /gene="hdeA"
                     /locus_tag="LSX49_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HBL7168837.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKKASFKDKVKGE
                     WDKIKKDM"
     gene            9882..10208
                     /gene="hdeB"
                     /locus_tag="LSX49_002437"
     CDS             9882..10208
                     /gene="hdeB"
                     /locus_tag="LSX49_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HBL7168838.1"
                     /translation="MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            10272..10919
                     /locus_tag="LSX49_002438"
     CDS             10272..10919
                     /locus_tag="LSX49_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBL7168839.1"
                     /translation="MTAEFIIRLILAVIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLGHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(10971..11741)
                     /locus_tag="LSX49_002439"
     CDS             complement(10971..11741)
                     /locus_tag="LSX49_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter ATP-binding protein"
                     /protein_id="HBL7168840.1"
                     /translation="MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLL
                     RQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHP
                     HRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLF
                     LDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCVLHDLNLAARYADRVVLMQKGKVIA
                     NGKPQDVLTQQALTMLYGADITVLKDPANHSPLIVLDH"
     gene            complement(11738..12694)
                     /gene="chuU"
                     /locus_tag="LSX49_002440"
     CDS             complement(11738..12694)
                     /gene="chuU"
                     /locus_tag="LSX49_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease ChuU"
                     /protein_id="HBL7168841.1"
                     /translation="MGLSLLLLALVLFGASQGALKISFDALFDEEYRDIWLNIRLPRV
                     LLAVLVGAALATAGVIMQGLFRNPMADPGLLGVSSGSALMVGVAIVLPFSFPVVLVLY
                     EQMVFAIAGSLVVCTIIFLITQRHRDGSMMQLLLAGIAINALCGAAIGILSYIGDEQQ
                     LRQLTLWMMGNLGQAQWPTLLVASSFILPAIIATTCLAGTLNLLQLGDEEAHYLGVNV
                     KRKRQQLLLVSSLLVGAAVSVSGIIGFIGLVIPHLIRMTTGANHRWLIPCSALAGACL
                     LLMADTLARTLVQPAEMPVGLLTSLLGGPYFMWLILRNRRIT"
     gene            complement(12779..13402)
                     /gene="chuY"
                     /locus_tag="LSX49_002441"
     CDS             complement(12779..13402)
                     /gene="chuY"
                     /locus_tag="LSX49_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobilin reductase"
                     /protein_id="HBL7168842.1"
                     /translation="MTPWLLFGAGGKGVGARTLELALAEQRPVVAVIRHADAATKLAQ
                     QGVQVFTGDACDASVVAAACRAAGPDALIISTMGGAQDYLAHRTVIDEAEKAGISRMI
                     LVTSLGCGDSWPFLSERAKAAFGQAVREKTLAESWLQTSQLDYAILRPGGLLDGAATG
                     KAQRIQNQECHGFVNRADVAAHIHELANAPALNQQVYSLIEPDLKPA"
     gene            complement(13402..13896)
                     /gene="hutX"
                     /locus_tag="LSX49_002442"
     CDS             complement(13402..13896)
                     /gene="hutX"
                     /locus_tag="LSX49_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme utilization cystosolic carrier protein
                     HutX"
                     /protein_id="HBL7168843.1"
                     /translation="MSHVSLQEFLKTEPDGTLEAIAEQYNTTLLEVVKNLPSPTVVSG
                     DKFDTVWDTVCEWGNVTTLVHTTDVILEFSGELPSGFHRHGYFNLRGKHGMSGHIKAE
                     NCTHIALIERKFMGMDTASILFFNKEGSAMLKIFLGRDDHRQLLSEQVSAFHALAASL
                     KEHA"
     gene            complement(13909..15246)
                     /locus_tag="LSX49_002443"
     CDS             complement(13909..15246)
                     /locus_tag="LSX49_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme anaerobic degradation radical SAM
                     methyltransferase ChuW/HutW"
                     /protein_id="HBL7168844.1"
                     /translation="MNTNNTLDLTPHFALDGDQPFKDRRAMMPFRGAIPVAKEQLVQT
                     WQEMINQTVSPRKRLVYLHIPFCATHCTFCGFYQNRFNEDVCAHYTDALIREIELEAD
                     SVLHQSGPIHAVYFGGGTPSALSAHDLARIITTLREKLPLAPDCEITIEGRVLNFDAE
                     RIDACLDAGANRFSIGIQSFNSKIRKKMARTSDGPTAIAFMESLVKRDRAAVVCDLLF
                     GLPGQDAQTWGEDLAIARDIGLDGVDLYALNVLPNTPLGKAVENGRTTVPSPAERRDL
                     YLQGCDFMDDAGWRCISNSHWGRTTRERNLYNLLIKQGADCLAFGSGAGGSINGYSWM
                     NERNLQTWHESVAAGKKPLMMIMRNAERNAQWRHTLQSGIETARVPLDELTPHAEKLA
                     PLLAQWHQKGLSRDASTCLRLTNEGRFWASNILQSLNELIQVLNAPAIALEKP"
     gene            complement(15266..16180)
                     /gene="chuT"
                     /locus_tag="LSX49_002444"
     CDS             complement(15266..16180)
                     /gene="chuT"
                     /locus_tag="LSX49_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312409.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     ChuT"
                     /protein_id="HBL7168845.1"
                     /translation="MPRIITRPFLFSPLTLCISAVVSAAKTMVKRKKLFTALLALSWT
                     FSVTAAERIVVAGGSLTELIYAMGAGKRVVGVDETTSYPPETAKLPHIGYWKQLSSEG
                     ILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVPATLEQMYANIRQLAKTLQVP
                     EQGEALVTQINQRLERVQQNVAAKKAPVKAMFILSAGGSAPQVAGKGSVADAILSLAG
                     AENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRSIAGITHTAAWKNQRII
                     TVDQNLILGMGPRIADVVESLHQQLWPQ"
     gene            16864..18846
                     /gene="chuA"
                     /locus_tag="LSX49_002445"
                     /gene_synonym="shuA"
     CDS             16864..18846
                     /gene="chuA"
                     /locus_tag="LSX49_002445"
                     /gene_synonym="shuA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent heme/hemoglobin receptor
                     ChuA/ShuA"
                     /protein_id="HBL7168846.1"
                     /translation="MSRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSF
                     EAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTGRTNGQDVNMRGYDHRGVLVL
                     VDGVRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQ
                     EGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPND
                     ESINNMLAKGTWQIDSAQSLSGLVRYYNNDAREPKNPQTVEASDSSNPMVDRSTIQRD
                     AQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTGSSGEYREQITKGARLENRSTLFAD
                     SFASHLLTYGGEYYRQEQHPGGATTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRY
                     DSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFS
                     IGRFYTNYWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASYFDTKAKDYIST
                     TVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEYISSINP
                     DTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSSYSKQPGYGVNDFYVSYQGQQALKG
                     MTTTLVLGNAFDKEYWSPQGIPQDGRNGKIFVSYQW"
     gene            18895..19923
                     /gene="chuS"
                     /locus_tag="LSX49_002446"
     CDS             18895..19923
                     /gene="chuS"
                     /locus_tag="LSX49_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hematinate-forming heme oxygenase ChuS"
                     /protein_id="HBL7168847.1"
                     /translation="MNHYTRWLELKEQNPGKYARDIAGLMNISEAELAFARVTHDAWR
                     MRGDIREILAALESVGETKCICRNEYAVHEQVGAFTNQHLNGHAGLILNPRALDLRLF
                     LNQWASVFHIKENTARGERQSIQFFDHQGDALLKVYATDNTDMAAWSELLARFITDEN
                     TPLELKAVDAPVVQTRADASVVEQEWRAMTDVHQFFTLLKRHNLTRQQAFNLVADDLA
                     CKVSNSALAQILESAQQDGNEIMVFVGNRGCVQIFTGVVEKVVPMKGWLNIFNPTFTL
                     HLLEESIAEAWVTRKPTSDGHVTSLELFAHDGTQIAQLYGQRTEGEQEQAQWRKQIAS
                     LIPEGVTA"
     gene            complement(19980..20510)
                     /locus_tag="LSX49_002447"
     CDS             complement(19980..20510)
                     /locus_tag="LSX49_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7168848.1"
                     /translation="MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVI
                     IDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTIAIIDFVALI
                     NGSYCSVPEADVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNL
                     KRINELVRHQHINYLV"
     gene            complement(20663..21229)
                     /gene="slp"
                     /locus_tag="LSX49_002448"
     CDS             complement(20663..21229)
                     /gene="slp"
                     /locus_tag="LSX49_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HBL7168849.1"
                     /translation="MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQ
                     PGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFL
                     DPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYG
                     YGAFWPEPGWGAPYYTNAVSQVTPELVK"
     gene            complement(21419..21798)
                     /locus_tag="LSX49_002449"
                     /pseudo
     CDS             complement(21419..21798)
                     /locus_tag="LSX49_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709288.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22415..22840)
                     /gene="arsC"
                     /locus_tag="LSX49_002450"
     CDS             complement(22415..22840)
                     /gene="arsC"
                     /locus_tag="LSX49_002450"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HBL7168850.1"
                     /translation="MSNITIYHNPACGTSRNALEMIRNSGTEPTIIYYLETPPTRDEL
                     VKLIADMGITVRALLRKNVEPYEELGLAEDKFTHDQLIDFMLQHPILINRPIVVTPQG
                     TRLCRPSEVVLEILPDAQKGAFTKEDGEKVVDEAGNRLK"
     gene            23175..23258
                     /locus_tag="LSX49_002451"
     CDS             23175..23258
                     /locus_tag="LSX49_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Damage inducible protein"
                     /protein_id="HBL7168851.1"
                     /translation="MIDKAIIVLGALIAQLELIRFLLQLLN"
     gene            complement(23312..24664)
                     /gene="gorA"
                     /locus_tag="LSX49_002452"
     CDS             complement(23312..24664)
                     /gene="gorA"
                     /locus_tag="LSX49_002452"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBL7168852.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTIEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNVEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCIGPEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(24736..25578)
                     /gene="rlmJ"
                     /locus_tag="LSX49_002453"
     CDS             complement(24736..25578)
                     /gene="rlmJ"
                     /locus_tag="LSX49_002453"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase"
                     /protein_id="HBL7168853.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDYPLLRSEFQKDNRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            25781..27823
                     /gene="prlC"
                     /locus_tag="LSX49_002454"
     CDS             25781..27823
                     /gene="prlC"
                     /locus_tag="LSX49_002454"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HBL7168854.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMELFKRFRGREPQLDAMLEHYGIKG"
     gene            27831..28583
                     /gene="rsmJ"
                     /locus_tag="LSX49_002455"
     CDS             27831..28583
                     /gene="rsmJ"
                     /locus_tag="LSX49_002455"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709277.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HBL7168855.1"
                     /translation="MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPAQLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(28632..30101)
                     /gene="dtpB"
                     /locus_tag="LSX49_002456"
     CDS             complement(28632..30101)
                     /gene="dtpB"
                     /locus_tag="LSX49_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HBL7168856.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADKFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     QLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(30418..30852)
                     /gene="uspA"
                     /locus_tag="LSX49_002457"
     CDS             complement(30418..30852)
                     /gene="uspA"
                     /locus_tag="LSX49_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HBL7168857.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            31243..31578
                     /gene="uspB"
                     /locus_tag="LSX49_002458"
     CDS             31243..31578
                     /gene="uspB"
                     /locus_tag="LSX49_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HBL7168858.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            complement(31649..33148)
                     /gene="pitA"
                     /locus_tag="LSX49_002459"
     CDS             complement(31649..33148)
                     /gene="pitA"
                     /locus_tag="LSX49_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HBL7168859.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
     gene            33380..34573
                     /locus_tag="LSX49_002460"
     CDS             33380..34573
                     /locus_tag="LSX49_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL7168860.1"
                     /translation="MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVAFRLRSEVLSVAKDDTGFTLELNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGTVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQTLISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLVAE"
     gene            complement(34660..35712)
                     /locus_tag="LSX49_002461"
     CDS             complement(34660..35712)
                     /locus_tag="LSX49_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 family protein"
                     /protein_id="HBL7168861.1"
                     /translation="MNIYIGWLFKLIPLLMGIICIALGEFVLTGSGQSEYFVAGHVLI
                     SLSAICLALFTTAFIIISQLTHGMNKFYNKLFPVIGYAGSATTMIWGWSLLASNNVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNASGSKSDGTPLQAYSSTIGNCLI
                     AVPVLLTLFGFIWSVILLRSADITPHYVAGHVLMGLTAICACLIGLVATIVHQTRNTF
                     SVKEHWLWCYWVILLGSLTIIFGIYVLISSDASARLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLAAFLAEIAQTDMAYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
BASE COUNT         9376 a         8512 c         8830 g         9095 t
ORIGIN      
        1 tcacgttgta aaaaccgaat gcccaacctt taaaaacagg tgggtattcg gctacttatt
       61 aattgcaata atatattacc tgtctattca tcgtgttgat aagatatatg ttatatgaat
      121 gttatggagc atagcgatac tgcttaatat tacgatgatg aattatttgc ttactattaa
      181 ttcctctgcg ttcttaagtc ccctttttat ataataaatc cagtcatcca gcccgagtat
      241 catcgctcat tatcatcctg ttttcccgct tcgtttaaat ttatttatca atcaatttga
      301 cttaagaggg cggcgtgcta cattaataaa cagtaatatg tttatgtaat attaagtcaa
      361 ctatgcaacc actacatggt aattgtctaa ttgcgtacgc aagacataaa tatattctca
      421 ccatggttaa tggtgaatat cgctatttta atggcggtga tctggttttt gcggatgcaa
      481 gccaaattca agtagataag tgtgttgaga atttcgtatt agtttcaaga gacacgcttt
      541 cattatttct cccgatgctc aaggaggagg cattaaaact tcatgtacat aaaaaagttc
      601 cttcattact cgttcatcac tgtaccagag atattcctgt ttttcaggaa gttgcgcaac
      661 tatcgcagaa taagaatctt cgctatgcag aaatgctacg taaaagggca ttaatctttg
      721 cgttgttatc tgtttttctt gaggatacgc agtttatacc gttacttctg aacgtgttgc
      781 aaccgaatat gcgaacacga gtttgtacgg tcatcaataa taatatcgcc catgagtgga
      841 cattagcccg aattgctagc gaattgttga tgagtccaag cctgttaaag aaaaaattgc
      901 gcgaagaagg tacgtcatat tcacagttgc ttactgagtg taggatgcag cgtgctttac
      961 aacttattgt tatatatggg gtttcaatta agcgagttgc agtatcctgt ggatatcaca
     1021 gcgtgtcgta tttcatttac gtttttcgaa attattatgg gatgacgccc acagagtatc
     1081 aggagcgatc ggcgcaggaa ttaccgaact gtggctcggc ggcaagtatg gctgcgcaag
     1141 ggatttttta cggcactgac cgttctgcgg aaggaataag attatagagt tttactcaga
     1201 cataaaaaaa acccggcata ggggaccggg aagaggatag tctgccgtct ccagactaat
     1261 aaaccgttat aacactccct gttggcacgg gaaactttgt gctctcagta agttaaatat
     1321 aacttttact ggaaataaga tcagccattt ttttataaac ataagctata cgctgtgtga
     1381 aaatataatc gtgttgcatt tacttattat caattaactg ttatgcaaaa ctactttgtg
     1441 gataaaattt ggtcctacca aatatggcag tttttgcaca cagaaacagt ctggcgtcat
     1501 ttcattagta tactgacatt gaaataatcg cagtaatgaa atataaggga tagtcatggc
     1561 tcatgtctgc tcggtgatcc tcgttcgtcg ttcattcgat attcatcatg aacagcaaaa
     1621 aatatcgttg cataacgaga gtatcctgct gctggataaa aatttggcag acgattttgc
     1681 gttttgttca ctggatacgc gacggctgga tatcgaagag ctgacagttt gccattactt
     1741 acaaaatatt cgtcagttgc cacgcaattt aggattgcat agcaaagacc gtttgttaat
     1801 taaccagtca ccccccatac agctggtgac ggcgattttt gatagtttca atgacccccg
     1861 ggtcaattcg ccgatactga gcaaaatgct ctatctttcc tgtttatcaa tgttttctca
     1921 taagaaagaa ctgatcccct tacttttcaa tagtatcagt actgtttcag gaaaagttga
     1981 acgccttatt agctttgata tcgctaaacg ttggtatcta cgcgatatcg cagaaagaat
     2041 gtacaccagc gagagtctca tcaaaaaaaa gttgcaggat gaaaatacct gtttcagtaa
     2101 aatattactc gcctccagga tgtcgatggc cagacgatta ctcgagttac gtcaaatacc
     2161 tctgcatact attgcggaaa aatgtggcta tagcagtacg tcatacttta taaatacatt
     2221 tagacaatat tatggtgtaa cgccacatca gttttcgcaa cattcgccgg gtaccttttc
     2281 ctgacatatt tcgcatttga atattggtca ggatctcacg tctgcttcat gtgaaactct
     2341 ttcctgatga tttctgccgg gctaccggct agttctcttt cgcagtttgc caggcggtat
     2401 aggtattttc aggaggaaaa gactcggcat gtttgggatt attaagctaa caattcatac
     2461 gattacggga atgtgggtca gtattgtgct gttcaaattg atgacgaatg gctggagtgg
     2521 tttctacttt cagtgctgtg tactaagcct ggtattcctg acggttagct ggttgttgag
     2581 tggtgaatgg ttagcaggaa agagtaaggc tgaaccctca cgttcaacct tactctcatt
     2641 tacacgttac gcttttttaa agcgggcaaa gagatgttcc actacaacga aaaagaccgg
     2701 aacgaagtaa attgccagca ctgttgcggc aaacatcccg cccattacgc cggtacctac
     2761 cgcgttttgc gcgccagagc cggcaccatg actgataacc agcggcagca cgccgagaat
     2821 aaaggccaga gaagtcatca ggattgggcg taaacgcata cgcgctgctt cgatgattgc
     2881 ctctaccggt gttttccctt ctttctgcat catctcaacg gcaaattcga caatcaggat
     2941 ggcgttcttg gcggaaagcc cgatggtggt cagcaaacca acctggaagt aaacgtcatt
     3001 acttaagccg cgcagatcgg tggccagtaa tgcgccaacg acgcctaacg gaacaaccaa
     3061 catcaccgag aacggaattg accagctttc ataaagtgcg gcgagggcga ggaacaccac
     3121 gaccagtgaa atggcatata gcgcgggagc ctgatttgag gataacgctt cctgatacga
     3181 cagtccggtc catgagtagc cgacgcctgc cggaagtttt gcgaccaggt ctgccataaa
     3241 tttcatggcg tcaccggtac ttttcccggc agccgcttca cctaaaatct ccattgacgg
     3301 gatgccgttg tagcgttcca gtcgcggtga accataggtc cattcggtag acgaataggc
     3361 agaaagcggt gccatcgtgc cagaggcgtt gcgtacatac cattggttga tgttatccgg
     3421 caacatacgg aacggcgtgc ctgcctggac atacactttt ttcacccgcc cctggttgag
     3481 gaagtcgttc acgtagctgc tgccgaaggc ggtggaaatt gtctggttga tatcagacag
     3541 cgccacaccc atagcctcgg ctttcgcagc gttgacgttc actttgaaca tcggcgtatc
     3601 ttccaggccg ttcgggcgta ccccgatgac ctgattcggt gattgcgctg ccagtgataa
     3661 cagctcgttt cgcgcctggg tcagtttttc gtgccccaga ttgccgttgt ccagcagttc
     3721 catatcaaaa cctgacgcgg tatccagttc agccaccgcg ggtaagttga acgggaagac
     3781 gacggcttta ttgatactgc ttagcgcaat cattgcccgc tgaataatcg cggtaaccga
     3841 gttttcctcg ccgacacgtt cagaccacgg cttgaggctg ataaacgcca gaccgttgtt
     3901 ttgcccctga ccactgaagc caaagccacc aacggtaaac accgactgaa cattattttt
     3961 ctcttttgtc agataataat ccgtcacctg ttgtagcact ttcgtggtgt taaccatggt
     4021 tgcaccggaa ggtaactgcg cggtggtcat aaataccccc tgatcctctt ctggtaagaa
     4081 agaggtcggc gtacgcagga acagcaccgc catcccggcg caaatcagta ggtagaccac
     4141 catgtagcga ccggtacaac gcaacagcga gcgggtgctg tcggtatagt gctgagttga
     4201 tttttcaaac agcgtgttga agcgtgcgaa cagggcgtta ggtttgtgac cgccctccgg
     4261 cgcggctttc agaatggtgg cgcacagggc aggggtcagg ctcattgcta caaatactga
     4321 aagcagcatg gaggagatca gcgtgatgga gaactggcgg tagatctccc cggtcgcacc
     4381 gctcataaag gccatcggca taaacactgc ggaaagaaca acggcaatcc cgaccagcgc
     4441 acgttggatc tgccccatcg atttatgcgt cgcttccttc ggcggtagct tatcttccgc
     4501 aatgacacgc tcgacgttct ccaccaccac gatggcgtca tccaccagta accctatcgc
     4561 cagcaccatc ccgaacatag ttaacgtgtt gatggtgaaa ccaactgccg acaagatcgc
     4621 aaacgtcccg agaataacca ccggtacggc aatcgtcggg atgattgtgg cgcggaaatt
     4681 ctgcaaaaac agatacatga ccaggaagac gaggatgata gcctcaacca gcgttttgaa
     4741 aacttcctga atagaaattt tgataaacgg tgtggtgtcg taaggataaa ccgtcttcag
     4801 gcttgcaggg aaataagccg ataaacggtt cagctcctct ttcaccgctc gcgaggtatc
     4861 cagggcgttt gctccggtag ccagtttgat ggcgatcccg gcggcaggtt tgccgttata
     4921 gcgcgccacg gtggaataat cttccgcccc aagttcgacg cgggcgacat cacgcagcag
     4981 cacttgcgaa ccatcttgct gaactttcaa caggattttg ccaaattctt ccggcgtttg
     5041 cagacgcgtc tgcacaatga tcgaggcgtt cagttgctgg tctgccgcct gtggcatgcc
     5101 acccagttga ccaccagaaa tctggttgtt ttgcacctta atctgggaaa taacatcgga
     5161 aggtaccagg ttatatttat tgagtttttg cgggtccagc cagatacgca tggcgtactc
     5221 ggaaccaaag agctgtacgc taccaacgcc cgcggtacgg cttagcgggt ctttgatatt
     5281 agacgctaca tagtccgcga tatcgtactg gttgaggctg ccgttatcag aaataaatgc
     5341 cgctaccatc aggatattac tgctcgactt atcgacgcta atcccctgct gctgcaccgc
     5401 ttcaggtaat gaaggcatag cgagttgcag tttattttgc acctgaacct gtgcgatatc
     5461 aggcgatgtc cccgtctcga aggtcagagt gatggaggca ttacctgccg catcgctggt
     5521 tgaagacatg tacatcaggc catcaagccc attcatattt tgctcaatca cctgagtgac
     5581 cgagtcttct accgtttgcg catcggcacc cggataggtt gcgctgacgg taatggtcgg
     5641 tggcgcaatc tgcggatact gcgcaaccgg taagttcatg atcgccagac cgcctgcaag
     5701 catcataata atggcaagta cccaggcaaa aaccgggcga tcaataaaat agttagccat
     5761 gaaagtcccc ttaagcctgc aacgttattg tttcgattcg gtgctggcgt tttcctggct
     5821 ggaggaaatt gctcgtgctt tgatacccgg acgaatgcgt tgcaagccgg aaacgatcac
     5881 ccgatcgcca gcctgcaagc cagaggtgac aacccactgg tcgccgatgg ctttgctggc
     5941 ttcgatttcg cgtagctgca cgacatcgtc tttatccaga atgagtgccg ttgctttacc
     6001 ctgggcgttg tgggtgacgc cttcctgcgg caccagtaat acattctggc ggctaccttc
     6061 atccactaat gccgtaacat acatgccagg cagcaagtca ccatttgggt tggggaaaat
     6121 cgcccgtaac gtcacggagc ccgtggtttc atccaccgtc gggtcggaga atttcagcgt
     6181 gccggtctgg ccgtaacgtt taccattttc cagattgagc tgtactggcg tactgccctg
     6241 aacctgtttg atttgcccac tggcgacctc ttctttcatg cgcaagaaat cctgcaccga
     6301 ctgcgtgaga tcgacataaa tcgggtccag acgttgtacg gtaaccagcg aatctgcctg
     6361 attagcggta acgagtgcgc cgacggtcac cgacgatttc ccgctgacgc ccgtaatcgg
     6421 cgaggtgaca ttcgcgtatt gcagattgat cgtcgcctgt tcaacagccg ctttggcgac
     6481 ggtgacattg gcttctgctt cattcaactg ggtgcgcgcg gtgtcgtaat cctgacggct
     6541 aacatagttg gtcttcagca acgatgcctg gcggttaaag gtgatgcggg cattgctggc
     6601 ggtagagagc gctttcgcca gcgagccttt ggcggagttc agctctgcct gtaaaggcgc
     6661 aggatcaatc tgatacagcg aatcgccctg gttcacttta tcgccttcga taaagttgcg
     6721 tttaatgata attccgccca cctggggacg tatctcggca acttcataag gaacggttct
     6781 accgggcaat tcgctcaaca cattgaccga accgggggag agtgtgacga caccgacctc
     6841 aggcgtcatg gcggcggcgt tttccgccga tttgtcatcg caggcggtga gcatcgcgcc
     6901 gcagaataac aacggtatta acagttttct tcttctgttc attttagtcc ctgaaaattc
     6961 ttgagaaata acggttcttt aaattgcgcg cgaggagaga tatgagggat ttacagacca
     7021 gcggcatagt ggggttgtca gccagtaaga tgggatgcaa gcacagtgat cgacatggtg
     7081 aggtcaacga caaaaaaaat gttgccgttc tgccaacagt ttctgccagc attcgggcaa
     7141 cgaagggttc tactggtgga tacacatacc aggggaataa agtcgttttc gtctctcctt
     7201 caataatcac cgggggtatt gaaatcagca tctgcatccc tcgtcatgcc agccatcaat
     7261 ttcagttgct tatgtcctta ctaaaaataa gatgtgatac ccagggtgac gatgtcgctc
     7321 atacgtctta atttcagctt gtacataatg ttgaatttct gaatctttaa tgtttgttgc
     7381 gaaatgttga gcgttgacgt gatattgctt tcatttttgt ttttcagaat cagttgcata
     7441 attttgaact gattatgtga aaaacatagt tgtgaattct tatggggcaa gtgtttacca
     7501 taagtaatct caagaagatt tttgatactt tctttacggc tgacaaaata aataggcgct
     7561 ttagctttta gtttactgat gtgataaggt gccaaaacaa taattctctc ggcatctaat
     7621 ttctccagga atttaatcgc ttcttcatca aggatatggt tgtgataggt gtcaatgatc
     7681 accttgaagg gtttattgcc tacttttttg atctctgaca gggaattgat ttttatcatt
     7741 tcgtgattat ctttcaactg ccaaaagccc tgtaaaagaa aagaatcttt cgtcatgaga
     7801 aaaatcataa cttgctcctt agccgttatc gtttcgaaca tgtcatcctt ttcattattt
     7861 acatccttgt ccgaatcgtt gttcaatata gtaaacgcct ataagaactt tgcccttcgt
     7921 gaactaatac gtctattaac actaatcaat acttcagatt tatccatcac gcactccata
     7981 tattggtcct aagtaagatt cctggttgtt atcagtttgt aactagtaaa caaaaggtta
     8041 acttttgcgg attactgccc aagaataagt tatcaataac cagtttgtga tctctgaaga
     8101 atattactaa agttaaaatg taatccgatt taaatatcga gtctccttgt ttcgacttag
     8161 gctggcaatt ggattgccag ctttctttta acgcattgaa attacctgat taaataactc
     8221 attcatgtct tcaggttttt atatagcgtc tggagacacg gatatttatg caatgtaatc
     8281 aacgccagtt gcaaaaaaat gaacccggat tacttattta accgcccata gcatcaacgc
     8341 ttacggaact ctttgttcac tttcccacag cacttttaaa acattaaacc tgaccacgga
     8401 aaatatcagc catgataatg tttgaaatgg ctaatttgcc atggaacgaa aaaaatcaga
     8461 ttaaattcag taggttgaaa taatcaacag caggcaattg tttcaatgat agtgcgtaat
     8521 tgaactgaaa cactgtatag ctaagagagt attaactgga tcatagtcac ttaatgtgac
     8581 tatgatccag gtggaaatag ggataattat tgctttttaa cgaacaaact ggcgaagctg
     8641 aacagactgg cggcgctaaa tatcagttca attcccacca gtgtggaaac cagcgttacc
     8701 gacaccatcg gcgtagcacc aaggaatatc caggcaatga cgatatccag cacaccaata
     8761 acgagctgta gccaactgcc tttcattgaa cgctgacgat accaactcat caggcgaata
     8821 acccctgcca cacagaacaa accggcaata aatgccgcaa tggcaaaaat gcccagctct
     8881 ggtgcgcgga tgaagaaata gccgatcaat aaataggcga ctgcgacgag gaaaccggat
     8941 aataccggcc agaaattatg actgcggttg ctgaatagcc cgacaataag cgcaatgccc
     9001 gagcagatta ataatgcacc cactactgtg cttaaaatgt cgccagagac gaacggaaaa
     9061 ctgatacaca gcaacccgac gataaacagc agcacggcaa taaactggat tgctctgcga
     9121 tgttttttaa gcatctccag atcaaacttc aaaattgttg ccttatctat atataacata
     9181 gaaccaccct ataaaattaa gaagaaaatc ccctgctatc aatctatgcc aaaaacgcgt
     9241 ctaagaatgc agtcgattta ataaaaattt cctaattaca gtatctgatg catctgtaac
     9301 tcattgtatt gaaataaaaa tatctgattt tgatattttc catcaacatg acatatacag
     9361 aaaaccaggt tataacctca gtgtcgaaat tgattcgtga cggctctttc actttatagt
     9421 tgaggatatt acgatgaaaa aagtattagg cgttattctt ggtggtctgc ttcttctgcc
     9481 agtagtgagc aatgcagcgg atgcacaaaa agcagctgat aacaaaaaac cggtcaactc
     9541 ctggacctgt gaagatttcc tggctgtgga cgaatccttc cagccaactg cagttggttt
     9601 tgctgaagca ctgaacaaca aagataaacc agaagatgcg gttttagatg ttcagggtat
     9661 tgcaaccgta accccagcta tcgttcaggc ttgtactcag gataaaaaag ccagctttaa
     9721 agataaagtt aaaggcgaat gggacaaaat taagaaagat atgtaattcc gggaatgcgt
     9781 tacatcgtat ttccttgcat attgaacagg ccggaatatc ttctttaaaa gcagctattc
     9841 ctcctgtttg tatataatct ctatattgaa tgggttacaa aatgaacatt tcatctctcc
     9901 gtaaagcgtt tatttttatg ggcgctgtag cggctttgtc actggtgaac gcacaatctg
     9961 cgctggcagc caatgaatcc gctaaagata tgacctgcca ggaatttatt gatctgaatc
    10021 caaaagcaat gacaccagtt gcgtggtgga tgctgcatga agaaacagta tataaaggtg
    10081 gcgataccgt tactttaaat gaaaccgatc tcactcaaat tcctaaagtg atcgaatact
    10141 gcaagaaaaa cccgcagaaa aatttgtata ccttcaaaaa tcaagcatct aatgacttgc
    10201 cgaattaatg aggtacaagt aaaaaggagt agcaagttga gccatcttgc tgctcctttt
    10261 tgcattttta tatgacagca gaatttatta tacgacttat acttgcggta attgcctgtg
    10321 gcgctattgg catggaaaga caaatgcgcg gcaaaggagc agggttacgc acacatgtat
    10381 taattggcat gggaagcgcc ctgtttatga ttgtttcgaa atatggtttt gctgacgtgc
    10441 tgtctttagg tcacgtcgga ctagacccca gccgtattgc tgctcaggtt gtgacgggcg
    10501 tcgggtttat cggtgcaggt aacattctcg ttcgtaacca aaatattgta ggtctgacga
    10561 cggcagcgga tatctgggtg accgccgcca ttggtatggt tattggcagc ggtatgtacg
    10621 aactgggtat ttatggttca gtgatgacct tgctggtgct ggaagtcttc catcaattaa
    10681 ccttccgcct gatgaacaaa aattaccatt tacagctgac attagtgaac ggtaatacgg
    10741 tatcaatgct cgactggttt aagcagcaaa aaataaaaac ggatttagtt tcgttgcagg
    10801 aaaatgaaga tcatgaagtg gtcgccattg atatccagct tcatgccacg acgtcgatag
    10861 aagatctgtt gcgattatta aaaggtatgg caggggtgaa aggcgtttca attagctaat
    10921 ctgtatagtt atttattcgc aggagtacca gtgcggtact cctgttggtt ttaatgatcg
    10981 aggacgatca gtggtgaatg gttggcagga tctttaagta cggtaatatc cgcgccgtag
    11041 agcattgtca gcgcctgctg tgtcaatacg tcctgcggct taccatttgc gataaccttt
    11101 cctttttgca ttaatacaac acggtctgca taacgcgcgg caagatttag atcgtgcaat
    11161 acgcagcaaa cattgaactg ccgttcgtga actaactggc gtaataaacg aaacaagtgc
    11221 tgctgatggt gaatatccag cgccgaagtt ggttcatcaa gaaataacca tttcggtgag
    11281 ggagtaggtt cccagagttg caccagcagg cgcgctaatt gcacgcgctg ttgttcacca
    11341 ccggataatt gccgatagtc gcggtttgct aacgcctgac agtcacataa cgccattatt
    11401 tgtgctgttt cattatcctg attaccagta cgatgcggat gccgccccat ctggataact
    11461 tcttgtacgc tgaatggaaa cgccatgtgg ctattttgac gcatcacggc ccggtgtttc
    11521 gccagttcag taatcgacca ttcatttaat ggcttattaa acaaccgaca ttcgccgcta
    11581 tcaggttgaa gatagccggt tagctggcga agcagcgtag attttcccgc accattaggg
    11641 ccgaggatgg caacaatttc cccaccggga aaagtcagcg agacattatc agtcagacgc
    11701 cgcccctgaa ggctataaac cagattctgg gcgctgatca tgtgatcctc cggttgcgca
    11761 gaatcaacca cataaaataa gggccaccaa gcaggctggt taataatccc acgggcattt
    11821 ctgctggctg taccagcgtg cgggcaagcg tgtctgccat cagcaataaa caggctccgg
    11881 cgagggcgga acaagggatt agccagcggt gatttgcccc ggtagtcatg cgaatcagat
    11941 gcgggatcac caggccaata aagccgataa taccgcttac cgatacggca gcaccaacga
    12001 gcagtgagct cactaacagt aattgctggc gtttacgctt aacgttcacg ccgaggtagt
    12061 gggcttcttc atcaccgagc tgcagtaaat tcagcgttcc ggcgagacaa gttgttgcga
    12121 taatggccgg taggatgaat gaactggcaa ccaataacgt cggccattgc gcctgtccaa
    12181 gattgcccat catccacaat gtgagttgtc gtagctgctg ctcatcgccg atatagctca
    12241 ggatgccgat cgctgcgccg cacagggcat tgatggcgat accggcgagt aataattgca
    12301 tcatgctgcc atcgcgatgg cgctgcgtga tgagaaaaat gatggtgcag accactaaac
    12361 ttccggcaat ggcaaacacc atttgctcat agagcaccag caccactggg aaggagaagg
    12421 gcagcacaat agcaacgcca accattaatg cagaaccgct actgacgcca agtaatccag
    12481 ggtcagccat tgggttgcga aaaagccctt gcataattac ccctgcggtt gccaacgctg
    12541 cacctaccag caccgccagc aaaacccgtg gtagacgaat attgagccag atatcgcggt
    12601 attcctcatc aaaaagggca tcaaaactga tctttaacgc tccctgactg gcaccaaaca
    12661 gcaccagagc tagcaataat agtgatagcc ccataaagac cctggcggaa gagagtgaat
    12721 ccttgagcac gcaaaactcc gttacgacat tacggcgcgg acatgccgcg ccgggggatc
    12781 acgccggttt caggtccggt tcaatcagac tgtagacctg ctggttaagt gctggcgcat
    12841 ttgccagttc atggatatgt gcggcgacat cagcacggtt aacaaaacca tgacactcct
    12901 gattttgtat ccgttgtgct ttgcccgttg ccgcaccatc aagcagaccg ccagggcgga
    12961 gaatggcata atcaagctgg ctggtttgca accagctttc cgccagcgtt ttttcccgta
    13021 ccgcctgacc aaacgcagcc tttgcccgct ctgataaaaa cggccagcta tcgccgcatc
    13081 ccaaagaggt caccagaatc atgcgactga tgccagcctt ctcggcctca tcaatcactg
    13141 ttctgtgcgc cagataatcc tgagctccgc ccattgttga gatgataagc gcatccgggc
    13201 cagctgcgcg gcaagcagcc gcgactacgc tggcatcaca ggcgtcgcct gtaaaaacct
    13261 gtacgccttg ttgcgccagt ttcgtggcgg catcggcatg acgaatgaca gcaacgaccg
    13321 gacgttgttc cgccagcgcc agttcaagcg ttctggcacc cacacctttt ccgcccgcac
    13381 caaagagtag ccacggtgtc atcaggcgtg ttcctttaac gatgctgcca gagcatggaa
    13441 ggcgctgact tgttcgctca ggagctgacg atgatcatcc ctaccgagga agattttcag
    13501 cattgcgctg ccttccttat tgaaaaagag aatagaggcg gtgtccatgc ccataaattt
    13561 acgttcgatc aaggcaatat gcgtgcagtt ttctgctttg atatgcccgg acatgccgtg
    13621 ctttccgcgt aggttgaaat agccgtggcg atggaaaccc gaaggcagtt cgccgctaaa
    13681 ttcgagtatt acatcggtag tatgtactaa cgtggtgacg ttgccccatt cgcagacggt
    13741 atcccagaca gtatcgaatt tatcacctga cacaacagtc ggagagggca gatttttcac
    13801 tacctccagc agcgtggtgt tgtattgttc ggcgatcgcc tccagcgtac cgtctggctc
    13861 cgttttcaaa aattcctgta acgagacatg gctcataaat cactcctgtt atggtttttc
    13921 aagcgcaatt gctggcgcat taagtacctg aatcagttca ttaagagact gcaaaatgtt
    13981 gcttgcccag aaacgacctt cattggtcaa ccgcagacac gttgacgcat cgcggcttaa
    14041 gcctttttgg tgccactggg ccagtaacgg cgcgagtttt tcggcatgtg gcgtaagttc
    14101 gtccagcggt acacgcgccg tttcaatgcc cgactgcaag gtatgacgcc actgcgcgtt
    14161 acgttcggcg ttacgcatga tcatcatcag cggttttttg cctgctgcga cggattcatg
    14221 ccaggtctga agattgcgtt cgttcatcca ggagtaacca ttaatcgaac cgccggctcc
    14281 ggaaccaaag gccagacaat cggcaccttg tttaatcagc aggttataga gattgcgttc
    14341 gcgtgtggta cggccccagt ggctgttact gatgcagcgc caaccggcat cgtccataaa
    14401 atcacaccct tgcaggtaaa gatcgcgacg ttctgccgga gagggcacgg tagtacgccc
    14461 attttccacg gctttgccca gcggtgtatt gggcaggaca ttgagcgcat agagatcgac
    14521 gccgtcgaga ccgatatcgc gggcaatagc cagatcttct ccccaggttt gcgcatcctg
    14581 acccggcaga ccaaacagca ggtcacagac caccgcggca cggtcgcgtt tgaccaggct
    14641 ttccataaac gcaatagcgg ttgggccatc cgaggtgcgg gccattttct tgcggatttt
    14701 gctgttaaac gactgaatac caattgagaa gcggtttgct ccagcatcaa ggcaagcatc
    14761 gattcgctca gcgtcaaaat tcagtacccg gccttcgata gtgatttcac aatcaggggc
    14821 cagtggcaac ttttctcgta atgtggtgat gattctggcc aaatcgtgtg ctgaaagcgc
    14881 ggaaggcgta ccgccaccga aatagaccgc gtggatgggg cccgactgat gcaatacgct
    14941 gtctgcttcc agttctattt cacgaatcag ggcgtcggta taatgagcac acacatcttc
    15001 attaaaacgg ttctgataaa aaccacaaaa tgtgcagtgt gtcgcacaaa aaggaatgtg
    15061 taggtaaacc agtcgcttac gtggtgatac cgtttgattg atcatctctt gccaggtctg
    15121 taccagttgc tctttggcaa ccggaatggc cccacgaaac ggcatcatgg cgcgcctgtc
    15181 tttaaagggc tgatcaccgt ctaaagcaaa atgtggcgtg agatccaggg tgttatttgt
    15241 gttcattcgt ctgatttaaa tccatttatt gcggccaaag ctgctggtgt aaagactcaa
    15301 cgacatcagc aatacgcgga cccattccca gaatcaggtt ttgatcaacg gtgataatgc
    15361 gctggttttt ccatgcggca gtgtgggtaa ttccggcaat agaacgtagc cgattaatat
    15421 cgccatcgac catttgtgag gtgacgacaa tcacttcagg gttagccgca atcagcgatt
    15481 ccgcgctgta gcttttgtac tgctggtggg tagcgacgtt ttctgctccg gcaagcgaaa
    15541 gaatggcgtc cgcgacgctg cctttaccgg caacctgtgg cgcacttccg cctgcggaga
    15601 gaataaacat ggctttaacc ggggcttttt tggccgccac gttttgctgt actcgctcca
    15661 ggcgttggtt gatctgtgtc accagcgcct cgccttgttc aggaacctgt aacgtttttg
    15721 ccagttggcg aatgttggcg tacatctgct caagggtggc tggtacacgc ggcagagtga
    15781 cgacgttgac tttttgcgcc cgcagttggt cgagcacaat ttgcggtcct gcatcctgcc
    15841 aggtaattac gctatccggg cgaagtgaca aaatgccttc gctgctgagt tgtttccagt
    15901 aaccaatatg cggcagtttg gcggtttctg gtggatagga tgtcgtttca tcgacaccaa
    15961 ccacgcgttt gccagcgccc atcgcgtaga ttagctccgt cagcgatcct cctgcgacca
    16021 cgatacgttc ggcagccgtt acgctaaaag tccagctaag agccagtaat gccgtaaaca
    16081 atttttttcg ttttaccatg gtcttcgcgg cagagaccac ggctgaaata cataacgtta
    16141 gtggggaaaa aagaaacggc ctggtgatga tccttggcat aatgtgagaa ctcttatcaa
    16201 attgagaatg atcatgatta tcatttgagt tatatatgaa atacaaccgt cgattcaata
    16261 cgcacggcgt tacaagcgta tttatttttg atttttatca agatgcttcg tcagctaatg
    16321 ttcttgttac cgattaaatt tcagcgcggg aaaaagctga gaacccggag atatcgcggc
    16381 ttgcagagca aagagaagag aaaattatca ctgttaacga caacgttttg tgatgaggtt
    16441 gtggggggat agccataaac acaggatggt tttctggatg ctggatagat ttcataaccc
    16501 cctgtttatt gtgttaatgg cggttaaaaa aagcttgatc ataaaaaatt gatcgataat
    16561 aattctcatt atcacgtttg agtttaacaa aatatgacat catggataac aaaatcatat
    16621 cttttgtaag ggaaaacgca cagcactctt cacttcagac gtggcgtact actttgcctg
    16681 acaaagaggg cgtgcttttg ctgaattatc agaaatattc ggcaatttta cgggatatat
    16741 acgctaatag cttcccgtgg tgatatctaa tcatttgaat tgtaaataaa tttatttttc
    16801 gccagccacc ccggtattaa cccaggcagc cagcattttt tattttcctc atggagaatc
    16861 gctatgtcac gtccgcaatt tacttcgttg cgtttgagtt tgttggcttt ggctgtttct
    16921 gccaccttgc caacgtttgc ttttgctact gaaaccatga ccgttacggc aacggggaat
    16981 gcacgtagtt ccttcgaagc gcctatgatg gtcagcgtta tcgacacttc cgctcctgaa
    17041 aatcaaactg ctacttcagc cactgatttg ctgcgtcatg ttcctggaat tactcttgat
    17101 ggtaccggac gaaccaacgg tcaggatgta aatatgcgtg gctatgatca tcgcggcgtg
    17161 ctggttcttg tcgatggtgt tcgccaggga acggataccg gacacctgaa tggcactttt
    17221 ctcgatccgg cgctgatcaa gcgtgttgag attgttcgcg gaccttcagc attactgtat
    17281 ggcagtggcg cgctgggtgg agtgatctcc tacgatacgg tcgatgcaaa agatttattg
    17341 caggaaggac aaagcagtgg ttttcgtgtc tttggtactg gcggcacggg ggaccatagc
    17401 ctgggattag gcgcgagcgc gtttgggcga actgaaaatc tggatggtat tgtggcctgg
    17461 tccagtcgcg atcggggtga tttacgccag agcaatggtg aaaccgcgcc gaatgacgaa
    17521 tccattaata acatgctggc gaaagggacc tggcaaattg attcagccca gtctctgagc
    17581 ggtttagtgc gttactacaa caacgacgcg cgtgaaccaa aaaatccgca gactgttgaa
    17641 gcttctgata gcagcaaccc gatggtcgat cgttcaacaa ttcaacgcga tgcgcagctt
    17701 tcttataaac tcgccccgca gggtaacgac tggttaaatg cagatgcaaa aatatactgg
    17761 tcggaagtcc gtattaatgc gcaaaacacg gggagttcag gcgagtatcg tgaacagata
    17821 acaaaaggag caaggctgga gaaccgttcc actctatttg ccgacagttt cgcttctcac
    17881 ttactgacat atggcggtga gtattatcgt caggaacaac atccgggtgg cgcgacgacg
    17941 ggcttcccgc aagcaaaaat cgattttagc tctggctggc tacaagatga gatcacctta
    18001 cgcgatctgc cgattaccct gcttggcgga acccgctatg acagttatcg cggtagcagc
    18061 gacggctaca aagatgttga tgccgacaaa tggtcatctc gtgcggggat gactatcaac
    18121 ccgaccaact ggctgatgtt atttggctca tatgctcagg cattccgcgc cccgacgatg
    18181 ggcgaaatgt ataatgattc taaacacttc tcgattggtc gcttctatac caactattgg
    18241 gtgccaaacc cgaacttacg tccggaaact aacgaaactc aggagtacgg ttttgggcta
    18301 cgttttgatg acctgatgtt gtccaatgat gctctggaat ttaaagccag ctactttgat
    18361 accaaagcga aagattatat ctccacgacc gtcgatttcg cggcggcgac aactatgtcg
    18421 tataacgtcc cgaacgccaa aatctggggc tgggatgtga tgacgaaata taccactgat
    18481 ctgtttagcc ttgatgtggc ctataaccgt acccgcggca aagacaccga taccggggaa
    18541 tatatctcca gcattaaccc ggataccgtt accagtaccc tgaatattcc gatcgctcac
    18601 agtggcttct ctgttggttg ggtcggtacg tttgccgatc gctcaacaca tatcagcagc
    18661 agctacagca aacaacctgg ctatggtgtg aatgatttct acgtcagtta tcaaggacaa
    18721 caggcgctca aaggcatgac cactactctg gtattgggca acgccttcga taaagagtac
    18781 tggtcgccgc aaggcatccc acaggatggt cgtaacggaa aaattttcgt gagttatcaa
    18841 tggtaatcat ctgccccgat atttcggggc atttatctgg aaggaagaga gacaatgaac
    18901 cactacacac gctggcttga gttaaaagaa caaaatcccg gaaagtacgc gcgtgacatc
    18961 gcaggtttaa tgaatatcag cgaagcagaa ctggcatttg cgcgcgtcac gcacgacgcg
    19021 tggcggatgc gcggcgatat tcgtgaaatt ctggcggcgc tcgaaagtgt tggcgaaacc
    19081 aaatgtattt gccgtaatga atatgcagtc catgagcaag ttggtgcgtt cacaaaccag
    19141 catttgaacg gacatgccgg attgatcctc aatccgcgcg cgctggattt acgtctgttt
    19201 ctcaatcaat gggccagtgt tttccacatc aaagaaaaca cggcccgtgg cgaacgccag
    19261 agtattcagt tctttgatca tcagggcgat gcattactaa aagtttatgc caccgacaat
    19321 accgatatgg cggcatggag tgagcttctg gcacggttta tcaccgatga gaatacgccg
    19381 cttgagttaa aagccgttga tgcgccagtt gttcaaacgc gagccgatgc cagtgtggtc
    19441 gagcaagagt ggcgggcgat gaccgacgtt catcagtttt ttacgttgct caagcgtcac
    19501 aatctgacgc gccaacaggc gttcaatctg gtggcagacg atttggcctg caaagtatcc
    19561 aacagtgcgt tggcgcaaat tcttgaatct gcacagcagg atggcaatga aatcatggtg
    19621 tttgttggca accgtggctg cgtacagatt ttcaccggtg tggtagaaaa agtggtgcca
    19681 atgaaaggtt ggctgaatat tttcaacccg acgtttactc ttcatctatt agaagagagc
    19741 attgctgaag cctgggttac ccgtaaaccg accagcgatg gtcacgtaac cagtctggaa
    19801 ttgtttgccc atgatggtac gcagatagcg caactttatg gtcaacgtac agaaggtgaa
    19861 caggagcaag cgcaatggcg taagcaaatt gcttcgttga taccggaagg cgttactgca
    19921 taacgtataa ttaacgggag gtctggctgt tgctgggcct ctttatattg atcaatcgtt
    19981 cacaccagat aattaatatg ctgatggcgt accagctcat tgatccgctt aagattgagg
    20041 atcatcatga tattgtgttt atggcagtag aacgttttta gcgatatttt cagtttctcc
    20101 agaatatctt ccgttgtcat ttgattcgca atacagctca gaacctgatg ctgcttgcgc
    20161 gagagggaca catccgcttc aggcacagag cagtaactgc cattgatgag tgcgacaaag
    20221 tcgatgatgg cgatagttcg cggaacaaag gtcaccggta ctttccccag gcagcgttta
    20281 atattaaagg gggagaaaat aattacatgg acaggtttta atcgttcaat ttgagtgaga
    20341 aaattagaat gaaatacatt attcattaat gtatcaataa tgacgaaggc attctgatgc
    20401 aacattacgt cgatctcttc ttcgttctgt atatgaacga cattaccttt actcagaatg
    20461 tttttcatcg cggtgaaaaa catcgtatcc ctggtaatta taagaaacat aaccgactcc
    20521 tggtacggac attaacttta taatcagttt gccaaaggta attaacagga cagggcttat
    20581 aataatagtt agcttactgt gtattaattt gatgtaatgc atgatgcaga tgctgagaaa
    20641 gcatctgcat ctttcggtgg tgttatttga ccagctcagg tgttacctga ctcaccgcat
    20701 tggtgtagta aggagccccc cagcccggtt ccggccagaa tgcaccatag ccgtaatccc
    20761 acaggttata ggtggtatta accacttctc tcaaatgcca cacctggatg ccctgcatat
    20821 tcacttcgag gaagttatac gggactttat tgataaagcc aggttgttca ccctgaatgg
    20881 taccgaggat ggtaacaaag tgattacgat agttcactgg atcaaggaag ccgctttgtc
    20941 tggcgagcag tcggccctga tagttggctt caatatcagg cttcgcatag ctatccaacg
    21001 gtaatacagc gatttctaac aacgtatccg ttttgccatt gataacgttg ataaccttcc
    21061 caccaaagcg cgcttgttga ccaacatata accccggctg gttatgaaca gcaacaaaac
    21121 ttttttgaat atcaggttgg ttattgcctt tgatattttg cggaattgaa ctacatgcgg
    21181 caagcaaaaa tgaaaggctg aggatgagtg caccttttgt catgttcatg ttactatcct
    21241 tatcaacaaa tattaaaacc ataatagata tttctttata gttttcatct gattctgagg
    21301 cgatatgcct gatagtaacg taaacctgtc tgatgtttat atctcttctg tttagttgag
    21361 ctcagttaat ttttgggcgt ggcatgagta tccattgttc cataatttat attaggaggt
    21421 ttttaatctt ttcgtgtcta atgttattta tctgattaag tattgattgt gtcttttgcg
    21481 gaagtggtgt cgagcttatc gtttcaatgt tattaataag acttacaagt tgagcctcaa
    21541 ctttgagtag tctgcatttg tatatgtggt gttcgtatgg cacgcattaa tttgttggcg
    21601 ttgttgttgc gctaaatcaa attgtttaga ggtgtatcct tctccagaga atggggaatt
    21661 aatgggttgt tgttcttccc ggttatcaca aggccacttc ggtgtgtctg gcgttttaac
    21721 attatcggta tttgttgtgc agttataaat atcaccgtta tatgtattta ttacacctgg
    21781 ggtaaagtca attgacataa cattccttat tcatcatttg ttttatgcta agattttaaa
    21841 attggataat tagaacagga atggattttc ttctacatac agtaaatata atgcgtcata
    21901 tcttcctgat ataattacct ttgacttctc ttttatttcc atctggtaat atttgagtgc
    21961 aaaaaaaggc aataataata tcgcaaaaga aaacgttaac aactatcgaa aatgctcgtt
    22021 ttaaaaaggt atgatgttct ctgatagtgt gtgaagtgat atttttgtga tgttttagat
    22081 atgtaataat aaaatgggtt aacgtatgtt gaaattattt attgtgcaaa ccactgatag
    22141 atcataatcc agtacatctt tacagtgctg cactgtatcg ctgataacta agcagctcac
    22201 tgatacacca tgctggacgc gataattgga atctcacgca gggagtactg tgtaaatagc
    22261 aaaatcgcct gatgcgctac gactgtcagg cctacaaata acatacaatt catcgaatta
    22321 tcataacgtt gtaggtcgga taagacgcgt cagcgtcgca tccgacataa ataaagcgca
    22381 tttttctaac aacctgtggg ggaatatagc cgctttattt caggcgatta cccgcctcat
    22441 caaccacttt ctcgccatct tccttggtga acgcgccttt ttgcgcatct ggcagaattt
    22501 ccagcacgac ttctgaaggg cggcacaggc gagttccctg tggcgtcacc acaatcgggc
    22561 gattaatcag aatcgggtgc tgaagcataa agtcgattaa ctgatcgtga gtaaatttat
    22621 cttctgcaag gcccagttcc tcatacggct cgacgttttt acgcagcaac gcgcgtacgg
    22681 taatccccat atcggcaatg agttttacca gctcatcgcg cgtcggtggt gtttccagat
    22741 aatagataat ggtcggttct gtaccgctgt tgcggatcat ctccagcgca ttacgcgacg
    22801 taccgcaggc cgggttgtga taaatggtaa tgttgctcat atcagtatct cattacaatg
    22861 tgaaagagag gtgtagcgcc agcgccacca gcgttacaaa ccaaagcgga caagtcaaaa
    22921 acacatatgg tttaacgaat atgtaagtgt agagaaaggt gtaggtgtga attaagcgtt
    22981 gggcattcat ttgaaaggag gtctgaatca ggacgtaaaa aaaccgactt cgcgtcggtt
    23041 tttttactgt tcagccctga gttggtggct ctggctggag tgagatagcc cacatctaac
    23101 aatgagacat gctccgtgac aggcaatgga tgagtaagcg gatgcattct cactccatcg
    23161 catggagaaa acgggtgatt gataaagcaa tcatcgttct tggggcgtta attgcgcagc
    23221 tggaactgat ccgctttctg cttcagcttc tgaactgata gcggaaacgt agctaagggc
    23281 taagagcaca ctactcttag ccctttaaca tttaacgcat tgtcacgaac tcttctgctg
    23341 ctgtcgggtg aatggcaacc gtgttgtcga agtctttttt ggttgcaccc atcttcagcg
    23401 ccaccgcgaa gccctgcaac atttcgtcca taccaaaacc aatgccgtga ataccgacaa
    23461 tcttctcttc cggtccaatg cataccagtt tcatgcgaca cggctggcgg tgagtggtga
    23521 cggcggtata catcgcggtg aaagaggatt tatacacttt cacctgatcg tcgccgtact
    23581 gctcgcgcgc ctgcggctcc gttaaaccaa cagtaccaat cggcggatgg ctgaagacca
    23641 cggtcggaat gttgctgtaa tccagatgct catccggctt gttattaaac aggcgttcag
    23701 agagacggcg acctgctgca actgccaccg gagtcagttc cactgcaccc gtgttatcgc
    23761 ccaccgcgta aataccttca acgttggtgt tttgatattt atcgacgacg atatagcctt
    23821 tttcgttggt tttaacgcca gcggcttcca ggttgatgtt gtcattggca ggctcgcgac
    23881 caatcgccca aatcaggcaa tccaccgttt cactgcgacc atcttccagc tccagcgtca
    23941 ggctgccgtc ggcatttttc accaccgctt tcgggatggc gttggtatgc aactgtgggc
    24001 cttcggcgtt catcacttcg accagcgttt cagagatcat cgggtcgaag ctgcgcagcg
    24061 gcgcatgttt acgcacaaac agatgcgtct tcgcaccgag gccgttaatc acgcccgcca
    24121 gttcaacggc gatgtaaccc gcgccaacaa ccgctacgcg ctctggcaaa gccggaaggg
    24181 cgaagaagcc atcagaatca ataccgtatt ccacgcccgg aatatccggg tggctcggac
    24241 gaccaccggt ggcgatcaga atatgatcgg ccgtgatggt ttcgccgttg acttcaatgg
    24301 ttttggcatc aacgaagcgg gcaaagcctt tgattacatc aacgttattt ttaccgagca
    24361 cgttctcata ggaagtatga atacggtcga tataggcggt acggctggcg atcaatgttt
    24421 cccagttgaa tttattgata gtggtatcaa agccgtaatc cgggccgtac atatggatcg
    24481 cttcacggat ttgtgccgcg tgccacatca cttttttcgg cacacagcca acatttacgc
    24541 aggtgccgcc cagctctttg gcttcaatca gtgcgcattt ctggccgtac atagccgcgc
    24601 ggttgatgga ggcgataccg ccgctgccgc cgccgatggc gatgtaatca tagtgtttag
    24661 tcatgacata ttgtccttat cgttgattac cgcgattgta gcgcgagacg taataggtgc
    24721 cagcaatggc tgcaattact ctggcacgat ccagcttacg gtggcgtgcc cggtgcctgc
    24781 tggaaccagt ttgctgtgca gccacggcag cacgttattc atctgctgtt ccagcttcca
    24841 cggcgggtta atcacaatca tgccggaagc ggtcatgcca cggcgatcgc tgtctggcag
    24901 caccgccagt tcaatttgca gaattttgcg aatgccggtc gcttccaggt cgtggatcat
    24961 gcgcttaatc tgctggcgca gcaccactgg ataccacaat gcgtaagtgc cagtggcgaa
    25021 acgtttgtaa ccttctgcta tcccgctgac caccgcctga tagtcggttt tcatttcata
    25081 cggcggatcg ataaggatta aaccacggcg ggaaaccggc ggtagtttgg ccttaagctg
    25141 ctggaaaccg tcggcttttt caacgcgcgc acgattgtct ttctggaatt ccgaacgtaa
    25201 caacggataa tcgctcgggt gcagttcagt cagttgcagg ctgtcctgtt cacgcagtag
    25261 ctggcgcgca atcaacggcg aaccggggta ataacgcaac tgcccgctac ggttgaagtg
    25321 ttttaccaca ttgatgtacg cctccagctc cgcaggcaaa tcgtcctgct gccagatacg
    25381 ggcgatacct tcgagatatt cgccggtacg ctcggcatgt tcgctgccta actgataacg
    25441 cccggcccct gcgtgggtgt cgagatagag aaacggttta tctttctctt tcagcgactc
    25501 gatgatcagg ctctgaacgg tatgtttaag gacgtcggcg tggttgccag cgtgaaagct
    25561 gtggcgataa ctgagcatgg gtaaaggtgt tccggtaagt aaaaatcggc ccgtattcgg
    25621 ggcgcacaaa agtctatcag gacagtatac cgaaaagagg ccgccgccgc gaaagcgtaa
    25681 cgtttctcat tgaaattcac tacacttaac cccatgctac aaacattatg taaagcgcct
    25741 gttgagcgct tccttaacct ctttaaccag gactgcgcta atgacgaatc cgttactgac
    25801 tccctttgaa ttgcctccgt tttctaaaat tctcccggaa catgtcgttc cagccgtgac
    25861 taaggcgctg aacgactgcc gcgaaaatgt ggagcgcgta gtagcgcaag gggcaccgta
    25921 cacctgggaa aatctctgcc agccgttggc ggaagtggac gatgtgctgg ggcgtatctt
    25981 ctccccggtc agccatctga actcggtgaa aaatagcccg gaactgcgtg aagcgtacga
    26041 acaaaccctg ccgctgctgt cagaatacag cacctgggta ggacaacatg aagggctgta
    26101 taaagcatat cgcgacctgc gcgatggcga tcattacgcc acgctgaaca cggcgcagaa
    26161 aaaagcggtt gataacgcac tgcgcgactt cgaactctct ggcatcggtc tgccgaaaga
    26221 gaaacagcag cgttacggcg aaattgccac tcgtctttct gaactgggca atcagtacag
    26281 caacaacgtc ctcgatgcga cgatgggctg gaccaaactc gttaccgacg aagcggagct
    26341 ggcggggatg ccagaaagcg cgctggctgc ggcaaaagcc caggccgaag cgaaagagct
    26401 ggaaggttat ttgctgacgc tggatatccc aagctacctg ccggtaatga cctactgcga
    26461 caaccaggcc ctgcgtgaag agatgtatcg tgcttatagc actcgtgctt ccgatcaagg
    26521 tccgaacgcc ggtaagtggg ataacagcaa ggtgatggaa gagatcctcg cgctgcgtca
    26581 cgaactggcg caactgctgg gctttgaaaa ctacgccttc aaatcacttg ccactaaaat
    26641 ggcagaaaac ccgcagcagg tgctggattt cttaaccgat ctggcaaaac gcgcgcgccc
    26701 gcaaggcgaa aaagagctgg cacaactgcg cgccttcgcc aaagccgaat ttggcgtcga
    26761 tgagttgcaa ccgtgggata tcgcttacta cagcgaaaaa cagaaacagc acctctacag
    26821 catcagcgat gaacaactgc gtccgtactt cccggaaaac aaagcggtta acggcttgtt
    26881 tgaagtggtg aaacgtattt acggcatcac cgctaaagag cgtaaagatg ttgatgtctg
    26941 gcatccggat gtacgtttct tcgaactata tgacgagaac aacgaactgc gcggtagctt
    27001 ctacctcgac ctgtatgccc gtgaaaacaa gcgcggcggg gcgtggatgg atgactgcgt
    27061 aggccagatg cgtaaagccg acggttcgct gcaaaaaccg gtcgcgtatc tgacctgcaa
    27121 cttcaaccgc ccggtaaatg gtaaaccggc gctgtttacc catgacgaag tgatcaccct
    27181 gttccacgag ttcggtcacg gcctgcacca tatgctgacc cgcattgaaa ccgctggtgt
    27241 ttccgggatc agtggggtgc cgtgggatgc ggtcgaactg ccgagccagt ttatggaaaa
    27301 ctggtgctgg gagccggagg cgctggcgtt tatctccggt cactatgaaa ccggcgagcc
    27361 gctgccgaaa gagttgctgg ataaaatgtt ggcagcgaaa aattaccagg cggcgctgtt
    27421 tattctgcgc cagctggagt tcggcctgtt cgatttccgc ctccatgccg agttccgtcc
    27481 ggatcagggg gcgaaaatcc tcgaaactct ggcagaaatc aagaaactgg ttgccgtggt
    27541 accgtctccg tcatggggcc gtttcccgca tgctttcagc cacatttttg ccggtggtta
    27601 tgcggcaggt tactacagct acctgtgggc cgatgtactg gcggcagatg ccttctcgcg
    27661 ttttgaggaa gagggcattt tcaaccgtga aactgggcag tcgttcctcg acaacattct
    27721 gagccgtggc ggttcagaag agccgatgga gctgttcaaa cgcttccgtg gtcgtgaacc
    27781 acagctggat gcgatgctgg agcattacgg cattaagggc tgatcattca gtgaaaatct
    27841 gcttaattga tgaaacaggc gccggagacg gcgccttatc tgttctggcg gcccgctggg
    27901 ggctggaaca cgatgaagac aacctgatgg cgctggtgtt aacgccggag catctggaac
    27961 tgcgcaagcg tgatgagccg aaacttggcg gcatctttgt tgattttgtt ggcggagcga
    28021 tggcgcaccg acgcaaattc ggcggtggtc gcggagaggc ggtggcgaaa gcggtgggca
    28081 ttaaaggcga ttatttgccg gatgtggtgg acgccaccgc agggctgggg cgcgatgcct
    28141 ttgtgctggc ttcggtcggc tgccgcgtgc ggatgctgga gcgtaatcca gtggttgccg
    28201 cgttgctcga cgatggtctg gcgcgtggtt atgcggatgc ggaaatcggc ggctggttac
    28261 aggaacgttt gcagttgatt cacgcctcca gtctgacggc gctgagcgat atcaccccgc
    28321 gtccgcaggt agtttatctt gacccaatgt tcccgcataa gcagaaaagc gcgctggtga
    28381 aaaaagagat gcgcgtgttt cagtcgctgg tggggccgga tcttgatgcc gatggattgc
    28441 tggagcctgc gcagttgctg gcaaccaaac gcgtggtggt aaagcgtccg gactatgcgc
    28501 cgccgctggc gaatgtcgcc acgccaaacg cggtagtcac taaagggcat cgctttgata
    28561 tttatgccgg aacgccggtg taaaagtaaa gcggggtagc gataacgcta ccccgctttc
    28621 tgcaagaata attaatggct ttccggcgtc gcaatcatgc gtttcagcca cggcaccatc
    28681 aatagcatca ctactgcaac gcccagcgta accaggccaa tcttaccaaa cacgttggta
    28741 tagacgggca acgtctcaag tggatcggta atgttgtctg gtactgcggt aaatgttgcc
    28801 acatagccgc ccagcaagaa cgcggcagcc tgcgtcagga accacatccc gagaataaag
    28861 cccatcaaat gctgcggcac cagggcagca atcatcgcca ggccaagggc gctaataaac
    28921 agttcaccta agctctggaa taagtacacc agcacgataa accatggcga tgtcagccct
    28981 tgggcatccg caaaccacat tccagccgct gcagccgtca aaaagcccag tgagcacata
    29041 aacatgccga gagtaaactt catcggcatc gagagatctt tgcctttgtt acccagttgc
    29101 gtgtaaatgc ctgccagtat tgggctggcg agtaccaccc agaacgggtt aagcgcctgg
    29161 aagctgaccg ggttgatgga aaagccgaga atttcatgat gcacgttgtt gatggcaaag
    29221 aagttcagcg acgttggcat ctgggcgtag agaatgtaaa acaccaccgc ttcgagcatc
    29281 aggacaaagg cgacaaacat tttattgcgc ccggttttat ccagcttgaa tgcctgacga
    29341 aagaagatga tggtgacgac gatggagaga acaatcagca ccagattggc gacttctacg
    29401 ttgtgcatca gccaggcgca gacgaagatc atcaccacgc tgccaagtaa tacgtacaac
    29461 agtttactga agctcatcgg ccggaagtcg ggttcagaac caatatcttt caccattcca
    29521 cgacaggcga tgtaaaccag taatgcgata attaaccctg caccgcacag gttgtaggtg
    29581 actgaatagc cgaatttatc agcgatcaca ggggccagcg ataacgctat caacgagccg
    29641 atattgatcg acatatagaa cagggtgaat gcgccatcaa gccgtggatc tttcggcgga
    29701 tagcatttcg aaagcaagct ggctgggtta gctttaaaca ggccgttacc gacagcgata
    29761 gtccccaggg cgatgaaaat caggtcaggc ttaagtagcg acatgccggt catgaagtag
    29821 ccaatcgcca gcacaagtgc tccgagaaca atggtgcgtt tggttcccag caggtggtcg
    29881 ccaacatagc caccaatgga aatgaggcca tagaccagcg cagcaaaagc accaaaagtg
    29941 acaaaagcct gctcttgcga gaacccaagc tgtttaacga agaaaaccgc cagtacgccc
    30001 tgcacgccgt agtagccgaa tcgctcccat aactcgacaa aaaagatcat gaaaaatggg
    30061 cgaggttgct gcagcatccc catgggtgtt gttgtattca tatttattaa ccttccaata
    30121 ccatcctgaa aagtatgaac gcgtaaggga taacgcgcga aaaagtttac atctgtcaga
    30181 gattcttaat attgatgcgg cgaatagatt aatacactat tacaacagaa aataaccagc
    30241 tgatcacact aatgatagaa aatatgatgg tgttaaatgt tgtattggca ggggttttaa
    30301 ttgcgtacgc agaccgcagg ccagataagg cgtttacgct gcatcaggta acaaggcgcg
    30361 ccaaaaagca aaacgcccgc atatgcgggc gttcaggaac acgtcgtgga gggaagatta
    30421 ttcttcttcg tcgcgcagcg gaacaatcag catatcaacg tgaacggtgt tgatcagctg
    30481 acgtgcggaa gacatcagtt tgctccagaa gtcctggtgg tgaccacaaa ccaccagatc
    30541 catatcgtat ttcttgattg catcgaccag tacctggccc agatcgccgc tgccgctcag
    30601 ggtttcagtg attgggtagc ctgcattggt tgaaagctcg gtcagcgcat gatgtgtctc
    30661 ttcagagatg cgtttctgca tatcacccag attcacatcg ataagcccgg tgtataggtc
    30721 agagtagttt acatctacgt ggatcagaga aactttcgca ttgtaggggc gagccataga
    30781 gactgctttc tctaccagaa ctttgctttc cggggagagg tcgaccgcga tgagaatgtg
    30841 tttataagcc atagtgttac tccttccata aagttgtcga tgactggcca gctagcgttt
    30901 cttgtgccgt tacgtcaccc gcgtcctgcg aactacgtgc gcggggctaa cccagccgta
    30961 aagattcagt gttaagacca tccttacctt atagcgaccc ggatgatccg tcaatccgcc
    31021 ttgcttactc gttagataaa caaattttcg acatgaatat attgatagtg gttaaccttc
    31081 tggaaaaaaa acaacctgat ctcctacact atctatagag ccgctcggat gttggtcacc
    31141 acaaaagcgg tttctccagg acctggtgtt aactgattgg cagcgtatcg ggagcggtag
    31201 ccccggggtg gaactccgcg ggcaggtcgc cggggaggag gtatgataag caccgtcgca
    31261 ttattttggg ctttatgtgt cgtttgcatt gttaacatgg cgcgctattt ctcatcacta
    31321 cgcgcgttgt tagtggtact gcgtaactgc gatccattgc tctatcaata tgttgatgga
    31381 gggggctttt ttacctcaca tggccaacca aacaaacagg tgcgtctcgt ttggtatatc
    31441 tatgcccaac gttatcgcga tcatcacgat gatgagttta ttcgccgctg tgagcgggtg
    31501 cgtcggcagt ttattctgac cagcgcattg tgtggtctgg tggtggtcag cctgattgca
    31561 ttgatgattt ggcattaagc acttcagcaa taatgacgca taaaaaaagc gggccagtaa
    31621 actgacccgc tcgttttggt gcgtacaatt acaggaactg caaggagagc cagtacagcc
    31681 cgccggaaag cagtaccgca gccggaaggg taaacaccca ggccatcaga atactggtta
    31741 cggttttacg ctgtaagccg ccgccatcta ccaccatcgt ccccgcgaca gaagaggaga
    31801 gtacgtgagt agtggaaacc ggcatcccgg tataacttgc caggccgata gacacagccg
    31861 ccgtcatctg ggcagacatc ccctgagcgt aggtcatgcc tttcttaccg attttctcac
    31921 cgatagtcgt tgccacacga cgccagccaa tcatcgtacc gatacctaac gccagcgcga
    31981 ccgccatgat gatccacacc ggcgcatact cgatggtgct aagcatgtcg gacttcagtt
    32041 tcttcaacag gcgctgatcg tcagcactca cgccaggcat tttcaccact ttatcgatag
    32101 tgtcagaaac gcacagcata atgcggcgca tctggctacg ttgatcaagc gacagcttgt
    32161 cgtagctttc cacatcggta gtcaacatgc ctttcaggcg gttgagcgcg ttaatggtat
    32221 tcgacggatg gcaatggaac tccgcgggtt gcgttgcgcc agcttccgga gccggtacta
    32281 actgatcagc accggtcgct tgtttcagca gtgcaggatg ctgctcaaag taagcttcga
    32341 cgttgttgat ggcatcacgg gtacgggtga tttcgtagcc agtggcattc atgttcacca
    32401 cgaagcctgc tggtgcgacg ccaatcaata ccaacataac cagaccaatg cctttctgac
    32461 catcgttcgc gccgtgcgaa aacgccacgc cgatagcgga aaggatcagc gcaatacgcg
    32521 tccagaacgg cggctttttc ttgccgtctt tcttttcacg ctccgctggg gtcaggtgga
    32581 tacgggcgcg tttcttggtg ccgctccagt agcgacgcag caagaaaatc agaccgccag
    32641 caaacaccag gccgacaata ggggaaacga tcagagaacc gaaaatactt aatactttcg
    32701 ggatattgag tgcatccacc actgacgtcc cggtcatcaa cgcattggtt aaaccaatcc
    32761 cgatgatcgc gccaatcagc gtatgagagc tggatgcagg taaaccaaag taccaggtac
    32821 ccaggttcca gataatcgcc gccagcaaca tagagaacac catggcaagg ccatgagacg
    32881 atcccatatt aagcagcaga tccgtcggca gcatatgcac aatggcatag gcaacactca
    32941 gaccacccag caaaacaccc aaaaagttga ataccgccgc cataaccacg gcgagctgag
    33001 aacgcatcgc gcgggtatag ataacggttg ccacggcgtt ggctgtgtca tggaaaccat
    33061 tgatggcttc gtagaacagc acaaaagcca gtgcaagcaa taataacagc ccggtatgca
    33121 aatccaggcc agcaaacaaa tgtagcatag gacgttacgc cattttgagg acatgaacgc
    33181 ggcgcattat cagtgacttt cgcggcgcgg gcaaagtgaa atatagactt tttttgattt
    33241 gcctcctgta tggattccac tcaaaaaata attatcttat ataattcagg caaatacttc
    33301 cttttagtaa tattgatgct ggtgcgacca ctgaggaatc tttacaattc acgcccgttt
    33361 tttcttagag gagcgcaacg tggaaaggtt tgatgccatt attataggcg ctggtgcggc
    33421 aggtatgttc tgttctgcgc tggcaggtca ggcaggacgc cgggttctgc tgatcgataa
    33481 tggtaaaaaa ccagggcgca aaatcctcat gtctggcggt gggcgctgca actttaccaa
    33541 cctttatgtc gaaccaggcg cttatctgag ccagaatccg catttttgta agtctgcact
    33601 cgcgcgtttt acccagtggg atttcattga tctggtcaat aaacacggca tcgcctggca
    33661 cgagaaaacg ttagggcagc tcttctgcga tgactccgcg cagcagattg tcgacatgct
    33721 ggtggatgag tgcgagaagg gcaatgtggc cttcagattg cgtagcgaag tgctgagcgt
    33781 ggcgaaggat gatacaggct tcacgcttga actgaacggc atgactgtcg gttgcgaaaa
    33841 gctggtcatt gcgaccggtg gactgtcaat gccggggctg ggcgcatcgc cgtttggtta
    33901 taagattgcc gaacaattcg gcctcaacgt gctgccgacc cgtgcgggtc tggtgccatt
    33961 cactctgcat aaaccgttgc ttgaagagtt acaggtgctg gcgggcgtgg ctgtgccttc
    34021 cgtgattacc gctgaaaacg gtaccgtttt ccgtgagaac ttactcttca cccaccgcgg
    34081 cttatctgga ccggcggtgt tgcagatttc cagctactgg caaccgggtg aatttgtcag
    34141 catcaatctg ctaccggatg tggacctcga aaccttcctg aatgagcagc gtaatgcaca
    34201 tccgaatcaa agcctgaaaa acacgctggc ggttcatctg ccgaagcggt tggttgaacg
    34261 gttacaacaa ctcgggcaaa tcccggatgt ctcgctaaaa cagctcaacg tgcgtgacca
    34321 acagacactg attagcacat tgactgactg gcgcgtacaa cccaacggca ctgaaggcta
    34381 tcgcactgcc gaagtgacgc tcggcggcgt ggacaccaac gaactctctt cacggacgat
    34441 ggaagcgcgc aaagtgcctg ggctgtactt catcggcgaa gtgatggacg tcaccggctg
    34501 gctggggggc tataacttcc agtgggcgtg gtcgagtgca tgggcttgtg cgcaggattt
    34561 ggtggcagaa taagaagcaa aatgcgctct cgataccaga gggattaacc tgaataaaac
    34621 cagataaggc gctcaacgcc ttatctgaag ccttttttat tattttttcg ctgaacccgc
    34681 ttctaatata gaaacgatgg aaaacagtgt aaaacaaact gcacctaagc caaccagaac
    34741 tcgcgaagga ataaagtaag ccatatcggt ttgcgcaatt tcagccagga acgcagcaag
    34801 gaacagacaa aacagacagg taaataccgg aatcatgggt attctgttgg ctaacgaaca
    34861 ggtgcgtcgc cataccagcg ctaacaacca cactttggag aaaatactgt agcagatcat
    34921 ccccaggcaa atgagaataa tgccgggggc caggcgggcg cttgcatctg aactgattaa
    34981 tacgtagata ccaaaaataa tggtaagtga gccaagcaaa ataacccaat agcaccacag
    35041 ccaatgttct ttcactgaga acgtattccg cgtttgatgg acaatagtgg cgacaaggcc
    35101 aataagacaa gcgcaaattg ccgttaaccc cattagtacg tgacctgcaa cataatgtgg
    35161 tgtgatatct gcactacgta acagtatgac tgaccaaatg aaaccaaaga gagtaagcag
    35221 aacgggaacg gcaattaaac aattaccgat tgttgaagaa taggcctgca atggcgtacc
    35281 gtcactctta ctgcccgagg cgtttttggg gatcaacaga aaatgtccgg aagatgccgc
    35341 tacggttgat acacaagcgg caatcatgcc aacgccgaaa ataacatgac cggcgacaaa
    35401 ttcatctgcc atcacattat tgcttgccaa cagtgaccat ccccaaatca tagttgtagc
    35461 agaaccggca taaccaataa caggaaataa cttgttgtag aatttattca tgccgtgagt
    35521 taactgagat ataataataa atgcggtagt gaacaatgcc agacatatcg cagaaagaga
    35581 aatcagaaca tgccctgcaa cgaaatattc actttgccca gaaccggtta atacaaactc
    35641 acctaatgcg atgcatatta tacccatcag taaaggaatt aatttaaaca accatccgat
    35701 atatatattc attttaaacc ccatatatat tttctgctac acttcgaaaa acatatgatt
    35761 cgtcttttca gttagttaaa tatgtctata agatgccatc aattaaaaaa agt
//
LOCUS       DAFGPF010000046        35355 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFGPF010000046 DAFGPF010000000
VERSION     DAFGPF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35355
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.046"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(81..980)
                     /gene="lysO"
                     /locus_tag="LSX49_002462"
     CDS             complement(81..980)
                     /gene="lysO"
                     /locus_tag="LSX49_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HBL7168862.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSTTVILLCNIAALMWLERGLPWSNHHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
     gene            complement(1395..2090)
                     /gene="aqpZ"
                     /locus_tag="LSX49_002463"
     CDS             complement(1395..2090)
                     /gene="aqpZ"
                     /locus_tag="LSX49_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HBL7168863.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRN"
     gene            2515..4173
                     /locus_tag="LSX49_002464"
     CDS             2515..4173
                     /locus_tag="LSX49_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HBL7168864.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENIPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(4170..5126)
                     /locus_tag="LSX49_002465"
     CDS             complement(4170..5126)
                     /locus_tag="LSX49_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001351020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF535 domain-containing protein"
                     /protein_id="HBL7168865.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFCS"
     gene            5277..6392
                     /gene="macA"
                     /locus_tag="LSX49_002466"
     CDS             5277..6392
                     /gene="macA"
                     /locus_tag="LSX49_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HBL7168866.1"
                     /translation="MKKRKTVKKRYVIAMVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDNAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKINDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            6389..8335
                     /gene="macB"
                     /locus_tag="LSX49_002467"
     CDS             6389..8335
                     /gene="macB"
                     /locus_tag="LSX49_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HBL7168867.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLEWKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVRNPPAIEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(8408..8632)
                     /gene="cspD"
                     /locus_tag="LSX49_002468"
     CDS             complement(8408..8632)
                     /gene="cspD"
                     /locus_tag="LSX49_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HBL7168868.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            8955..9275
                     /gene="clpS"
                     /locus_tag="LSX49_002469"
     CDS             8955..9275
                     /gene="clpS"
                     /locus_tag="LSX49_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HBL7168869.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            9306..11582
                     /gene="clpA"
                     /locus_tag="LSX49_002470"
     CDS             9306..11582
                     /gene="clpA"
                     /locus_tag="LSX49_002470"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HBL7168870.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(11926..12013)
                     /locus_tag="LSX49_002471"
     tRNA            complement(11926..12013)
                     /locus_tag="LSX49_002471"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11977..11979),aa:Ser,seq:gga)
     gene            complement(12267..12485)
                     /gene="infA"
                     /locus_tag="LSX49_002472"
     CDS             complement(12267..12485)
                     /gene="infA"
                     /locus_tag="LSX49_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBL7168871.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(12770..13474)
                     /gene="aat"
                     /locus_tag="LSX49_002473"
     CDS             complement(12770..13474)
                     /gene="aat"
                     /locus_tag="LSX49_002473"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HBL7168872.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFS
                     RMENASKTALLVFCDEFIRHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LSNNFWVPRCLFSPQE"
     gene            complement(13516..15237)
                     /gene="cydC"
                     /locus_tag="LSX49_002474"
     CDS             complement(13516..15237)
                     /gene="cydC"
                     /locus_tag="LSX49_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HBL7168873.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPKVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGIYLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEIL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(15238..17004)
                     /gene="cydD"
                     /locus_tag="LSX49_002475"
     CDS             complement(15238..17004)
                     /gene="cydD"
                     /locus_tag="LSX49_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HBL7168874.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLFLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQTALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(17127..18092)
                     /gene="trxB"
                     /locus_tag="LSX49_002476"
     CDS             complement(17127..18092)
                     /gene="trxB"
                     /locus_tag="LSX49_002476"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBL7168875.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNTDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
     gene            18636..19130
                     /gene="lrp"
                     /locus_tag="LSX49_002477"
     CDS             18636..19130
                     /gene="lrp"
                     /locus_tag="LSX49_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HBL7168876.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            19265..23371
                     /gene="ftsK"
                     /locus_tag="LSX49_002478"
     CDS             19265..23371
                     /gene="ftsK"
                     /locus_tag="LSX49_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL7168877.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDE
                     EITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWA
                     APVEPVTQTPPVASVDVPPAQSTVAWQPVPGPQTGEPVIAPAPEGYPQQPQYAQPAVQ
                     YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAAEQPAQQPYYAPA
                     PEQAVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPV
                     VEETKPTRPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVP
                     PVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKR
                     IRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFA
                     QTQQQRYGEQYQHDVPVNTEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDF
                     EFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPV
                     APQQQYQQPQQPVAQQPQYQQPQQPVTQQPQYQQPQQPVVPQPQYQQPQQPVAPQPQD
                     TLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADF
                     RIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPY
                     VGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAG
                     TTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDA
                     ANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQH
                     PVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVIT
                     GLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVR
                     DQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRK
                     ASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD"
     gene            23530..24141
                     /gene="lolA"
                     /locus_tag="LSX49_002479"
     CDS             23530..24141
                     /gene="lolA"
                     /locus_tag="LSX49_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HBL7168878.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            24152..25495
                     /gene="rarA"
                     /locus_tag="LSX49_002480"
                     /gene_synonym="mgsA"
     CDS             24152..25495
                     /gene="rarA"
                     /locus_tag="LSX49_002480"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HBL7168879.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAVGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            25586..26878
                     /gene="serS"
                     /locus_tag="LSX49_002481"
     CDS             25586..26878
                     /gene="serS"
                     /locus_tag="LSX49_002481"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBL7168880.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            complement(27184..27324)
                     /locus_tag="LSX49_002482"
     CDS             complement(27184..27324)
                     /locus_tag="LSX49_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HBL7168881.1"
                     /translation="MSQKSLTAITFCVTAILIIWMLHGSLCEIRMSFWGAEFAAFLQC
                     KQ"
     gene            complement(27516..27776)
                     /locus_tag="LSX49_002483"
     CDS             complement(27516..27776)
                     /locus_tag="LSX49_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001512982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HBL7168882.1"
                     /translation="MFRCPLCGASARIRTSRPENDSNTVRQKYYQCNNLECGVCFSTL
                     EAFHKFTSKHASGVHSSEGIPWHDLPASHRGNNQMSLPLSQN"
     gene            complement(27817..28926)
                     /locus_tag="LSX49_002484"
     CDS             complement(27817..28926)
                     /locus_tag="LSX49_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001494339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HBL7168883.1"
                     /translation="MTDTTMQLLSQGTDPVKMPDFDILAEGKTLSGVAERLMSLSLTD
                     NRGFEADQLTITLDDADGQLQLPPRGARLTVLIGWKGEPLTEKGTYIVDEIAHEGPPD
                     RLTVSARSADFRDEFNVKREVSWHDVTVERVVSAIAHRYGLKPQISEMLMDIEIDHAD
                     QTEESDMSFLTRMAEMLGAITTVKSGNLLFIMPGGGVNAQGQPLPSFAITRSSGDRHQ
                     FRIADREAYTGVRAYWLDLNYGKKKKVSVKRRKPPKPKKEKSSSREGDYMEGAEGNVF
                     VLRKTYQNEQAARRAAAAKWQQLQRGAASFSITLARGRAELYPEMHGTVTGFKSEIDN
                     QDWIIAKAEHTIDNSGFTTQLELEAKIPEWIAETE"
     gene            29084..30268
                     /locus_tag="LSX49_002485"
     CDS             29084..30268
                     /locus_tag="LSX49_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBL7168884.1"
                     /translation="MSETRFHGARVTESTDLVTAINDVDSSVIGIVATADDADAELFP
                     LNKPTLLTRVNDVLGKCGTTGTLYRALKAIADQVSTKVIVVRVAEHKEEGGRTQDQLV
                     IGGSESDGSYTGMYALLVAEQDESIGYRPRILAAPELDTEAVTKSLCVIAGKLRAFVY
                     ATCHGCNTMAEAITYRQKFNEREVMLLWPDFIAYNPKSGKNETFPAPAYACGLRAYID
                     HEQGWHKSLSNVPVKNVLGMSRHVFWSLQAEDSDANSLNNKEITTIIRRNGFRFWGNR
                     TPETNAYIFEVYTRTAQVLADSIAEAQFETIDSPLTPANVKDVISAIRAKLDSLVTAG
                     KLIGAECWYDVVDNGTTDLRQGRVRIRYKYTPVPPLEDMELYQTFTDEFFGPAFAVLG
                     GA"
     gene            30268..30780
                     /locus_tag="LSX49_002486"
     CDS             30268..30780
                     /locus_tag="LSX49_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HBL7168885.1"
                     /translation="MAVPKHLRFFTLFVDGENEVGKVTSVTPPKLTRKTDSYRGGGMM
                     GAVSIDLGLDDSALDASFVMGGAVRALFLKYGGTIDGTLLRFAGEYYTDAESDLYEIE
                     MRGRVTEIDMGEAKQGEATSHTYAVKNTYYKLSVNDRPLWEIDLLNHIYRKDGKDIVP
                     DRIRSALGLG"
     gene            30836..31210
                     /locus_tag="LSX49_002487"
     CDS             30836..31210
                     /locus_tag="LSX49_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7168886.1"
                     /translation="MKDIDTETRNNTVADDVTSGEDMAVERGVKLSRPIERGAEKITY
                     VEITGAIEQAGSLRGLSLSDVLNLKADTMFTLLPRVTSPRLDEVMIKKMSSRDFIQLC
                     AVAVNFMSEPDSGAKSVQETAA"
     gene            31219..31374
                     /locus_tag="LSX49_002488"
     CDS             31219..31374
                     /locus_tag="LSX49_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HBL7168887.1"
                     /translation="MCFEHIEDLVADIAAIFNWSPAEIFMMTPGEVVSWRERAALRSG
                     NADNEDS"
     gene            31361..34168
                     /locus_tag="LSX49_002489"
     CDS             31361..34168
                     /locus_tag="LSX49_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000853438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL7168888.1"
                     /translation="MKTLDIRVAFSAVDRLTRPAENARRLMGQFGDSIQRTQGAIKNL
                     ERQARSFERARDAVSKADAGIVKARRQLNALNQLQRTGTVLSEKQQKLMQQLSTRLER
                     LNESRTREIQKMRELGGELKRHGISLTGSDNTIQQAIRRTEQYNNQLERERQALARVT
                     QARERYSRAQETAGKLKTGGALAIGAAAAGGYAAGRFLQPAIGFGKEMSRVQALTRID
                     KNSPQFKALREQALKLGSETQFTASDAASGQSFLAMAGFTPQAIQAALPGVLNMALAG
                     GVELGETADIGSNILTQFNLTADQMDRVGDTLTAAFTRTNTDLRALGETMKYTGPVAA
                     KLGISLEEAAAMAGMLANNGLRGSDAGTAMRASLSRLASPPKAAADALKELGVSVADA
                     RGKMRPMEDVLLDLYKATQKYGQVDQVSFFKDIAGEEAFVGLQTLVAAAGSGELQKLT
                     RELQGARGEADRVAKVMADNLDGDLKNLDSAWEGLRIRISDLVDGPLRSVTQWLTRVL
                     EKITSLAQAHPVLTRQLLIAGGALLAMTATVGSLSLAIGVLAGPLAKLRLGFSLLTGS
                     MNAVRLLPALWGMVTGSVSLLGGAIGALFSPVGLIVAALAGAAVLIWKYWDPIRAFFA
                     GVFSGIMERLTPLRETFERFGPVFDAIGSGISQVFNWFKSLLSPMESSKETLDKCTSA
                     GEIFGNVLGGALQLVLTPAKMLLDTLAWILEKLGVLPDEAERARKKIEDAQRAAILQD
                     KVALLQGDLAKINPPKPVENGNGTGGDNPKDNKPLTDSNTGTLRRLSKIADNTGKLVE
                     ETKKRIGPGDIVFKNLPRALAVRGEWQERKIAQVSKPAPAINITPVVPAPLPPALVPV
                     VAASSRPVAEAIRSPVASVPVTSRNREPVASGFGGEIHVHLHNVVTQNPRELAKLVGE
                     MVRAEMERRARAGRGSFYDKD"
     gene            34181..34669
                     /locus_tag="LSX49_002490"
     CDS             34181..34669
                     /locus_tag="LSX49_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7168889.1"
                     /translation="MMMIYGMFVFELRTLPHQQLQQNKSWRHVKNERVNRSASWQYIG
                     AGDDRIVLSGVLYPEITGGEVSLSLLTTQAYTGRPWPLIDGVGQIYGMYVLTETNTTR
                     SEFDRYGKAKKIEFSLTLERCDEDLRERLQSSSFSDMLSGFKDKVTSSLNSAASSVKG
                     LF"
     gene            complement(34698..35297)
                     /locus_tag="LSX49_002491"
     CDS             complement(34698..35297)
                     /locus_tag="LSX49_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL7168890.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALVCAGCEQIFEDKLSGTKTDRPG
                     LKRALKRLQKGDTLVVWKLDRLGRSMKHLISLVGELRERGINFRSLTDSIDTSSPMGR
                     FFFHVMGALAEMERELIVERTLAGLAAARARGRTGGRRPKLTKEQHEQIARLIKNGHD
                     RKQLAIIYGIGTSTIYRYHPVGDIQTEETTGQTQENENR"
BASE COUNT         8743 a         8771 c         9596 g         8245 t
ORIGIN      
        1 taaaagagat ttttaatgca actttaaggg agattgattt agcgcaattt tggcggcaga
       61 gatctaccgc cagagaggta ttatgcagag aaaaaggcga tgagaatcgg cactaacaga
      121 ctaagaataa aaccgtgaac aatcgccgcc gggaccatat ccagcccgcc tgtacgttga
      181 agaacgggca gggtgaaatc catcgacgtc gcaccgcata agcccagtgc agtagagcgg
      241 ctacggcgaa tcagcccagg gattaacata atagcaatca gctcacgggc cagatcatta
      301 aaaaacgccg cgctcccgat taccggacca aaagattcgg tcaataaaat accggaaaga
      361 gaataccagc cgaaaccgga ggccattgcc agcgcggtat tgatgggaag atcaagaata
      421 aaggcgttaa ttaaaccacc aattaatgaa ctggcaacca ccaccacggc gacaatcatt
      481 ccccggcgat taaggacaat ctgctttaag gtcatgccat tattgcgcaa ctgaataccg
      541 acgaggaaaa gcagcagaat taaggtgtat tcactggctt cggtcgcgtg ttgtaagaaa
      601 gccagtccac tcagaccaat ggcaaaacca atcactacta cgccgcacag ttttagcgac
      661 tccagcgcca tcgcaatacg cgacgggagt ttttcttgct gatggtggtt gctccatggc
      721 aggccgcgct ccagccacat cagggcggca atattacaca gtaaaataac ggtagtactg
      781 acggcagaat aatgcagaat tgccaacaag ttactggcga ggttatcgag aaacgccaga
      841 ctgataccca taaaaaagag aataaggtaa accatccagc ttaagagctg attaataact
      901 cttaatgcag ctttttggcg aagcggaatg aggtaaccca caatcagggg aaccagaatg
      961 attaacagcc cagaaaacat gaaaacccag tccttgcaaa gaagattcga aatgcgcgat
     1021 gacacactac tgaaagcgga aggacgagta aagttgcaat taaaaggaaa tgttatgcat
     1081 aaggatcggt agggtattca ttttcattta aagatattct tgcgctttaa ttacaaaccg
     1141 caccggtgtt ggtggcgtca aaatcgccga cccggtagcc gtaagggata agtcgagggc
     1201 accgcgcagc ggcgattttg ttcgccagag cccgggggtg cagggggcgg cggcgattgg
     1261 ccgccccctg cacgctcctt gcgccagtgg caatatgtgg cttagctcat gaaaggagcg
     1321 caacaagatg atgaatcaac atataacaac atcttaaaaa aaggcctgac attgcgccag
     1381 gccttctgcg ttaattaatt acgcttttcc agtagagtcc ggtaaatcag accaccgata
     1441 ataccgccga caattggcac cacccagaag aaccacagtt gttctaatgc ccagccgccc
     1501 tggaagatag caaccgcagt actgcgcgcc gggttaacgg aagtgttagt caccggaata
     1561 ctgattaagt gaatcagggt taaggccaga ccaatggcaa ttggcgcaaa accagcagga
     1621 gcgaatttgt cagttgcgcc gtggatcacc agcaggaaac ctgcactcaa taccagttca
     1681 actaccagcg cggaaagcat ggaataaccg cctggtgaat gctcgccata accgttagaa
     1741 gcaaaaccgc tggctgccgc gtcaaaaccc gttttaccac tggcaattaa atacagcagc
     1801 gccgccgcaa caataccgcc gacaacctgg gcaattacgt agccaacgac ttcttttgcc
     1861 gggaaacgtc cgccagccca taaaccaata gtgaccgccg ggttaaaatg accaccagaa
     1921 atatgaccaa cagcaaaggc cattgtcaga acggtcagac cgaacgccaa cgccacgccg
     1981 gcaaaaccaa tgcctaattc cgggaagcct gcggccagta cggcactacc acagccgcca
     2041 aaaacaagcc agaaagtacc aaaacattca gctgctaatt ttctgaacat atccacctca
     2101 attaaaaatt gaccctgtga aaaatatggt cgttttatag ggtcgtcgta aaaaagtgac
     2161 gacggaaata atgcgcggct attttaaaaa cgaaggcaaa tcattcgcca gataaataaa
     2221 tccagtaaat ttgatttagg gcaacagcgg gttgccccat atagtcattt gtctgattga
     2281 cagtgtagtg caagcgaaag atttaatcct ttaggcgtaa taaaaaataa tttatcatgc
     2341 taattatttg attttgttgt ttttgcaggc ttatcagcaa gagggagtat aacgcgatta
     2401 ttcgctcatt tttcagacat ttgccatgct taaatgtgat gccatcacgt attagcaggc
     2461 ctttcccgtt atactgccag cgtaaagaat aagtcacata tttctggagg ggatatgatt
     2521 cttgagcgcg ttgaaattgt gggttttcgc ggtatcaacc gtttgtcgtt gatgctggaa
     2581 caaaacaacg tcctgattgg ggagaacgcg tggggtaaat ccagcttgct ggacgcctta
     2641 accctgctgc tatcgccaga atcagatctc taccattttg agcgcgatga tttctggttc
     2701 ccgccgggag atatcaacgg gcgagaacat catctgcata ttattttgac cttccgcgaa
     2761 tcgctgccag gccgacatcg ggttcgccgc tatcggccgc tggaagcgtg ctggacgcca
     2821 tgcaccgatg gttatcaccg tattttttat cgtctggaag gggagagtgc ggaagacggc
     2881 agcgtgatga cactgcgcag ttttctcgat aaagacggac atccgattga tgttgaggat
     2941 attaacgatc aggctcgtca tctggtgcgt ttaatgccgg tgctgcgctt gcgtgatgcc
     3001 cgttttatgc gccgtattcg taacggcacg gtgccaaatg tccccaatgt ggaagtcacc
     3061 gcgcgccagc tcgatttcct cgcccgtgag ttgtcctcac atccgcaaaa tctctctgat
     3121 ggacagattc gtcagggact ttccgcaatg gtgcaactgc ttgagcatta tttttctgag
     3181 cagggagctg gacaggcgcg atatcgttta atgcggcggc gagccagcaa tgagcaacga
     3241 agctggcgct atctggatat catcaaccgg atgattgacc gacctggagg gcgctcgtat
     3301 cgggttattt tgctcggcct gtttgctact ttgttgcagg caaaaggcac attgcgactg
     3361 gataaagacg cccgtccatt gttgctgatc gaagatccag aaacccgttt gcaccccatt
     3421 atgctttcag ttgcctggca tctgttgaac cttctgccat tgcagcgcat cgctactacc
     3481 aactcgggag agttgctttc gttaacgccg gtagagcatg tttgccgact ggtacgtgag
     3541 tcctctcgcg ttgccgcctg gcgtctggga ccgagtggct tgagtaccga agatagccga
     3601 cgcatctcct ttcacattcg ttttaaccgt ccgtcatcgc tgtttgcccg ttgttggctg
     3661 ctggtggaag gggaaacgga aacctgggtt atcaatgaac tggcgcgtca gtgcggacat
     3721 cattttgatg ccgaagggat caaggtcatt gagtttgccc agtccgggct aaagccactg
     3781 gttaaatttg cccggcgaat ggggattgaa tggcatgtac tggtcgatgg cgatgaagca
     3841 gggaagaaat atgccgctac ggtacgcagc ctgttgaata atgatcggga agccgaacga
     3901 gaacatttaa cggcgttacc ggcgctggat atggaacatt ttatgtatcg ccagggattt
     3961 tccgatgtgt tccaccgcgt ggcgcaaatc ccggaaaata taccgatgaa tctgcgcaaa
     4021 attatctcga aagcgatcca tcgctcttcc aaacccgatc ttgccattga agtggcaatg
     4081 gaggccggac gtcgtggtgt ggactccgta ccgacgctgc tgaaaaaaat gttctcacgc
     4141 gtgctgtggc tggcgcgcgg tcgggccgac taactacaaa acatcgtggc catttgtggc
     4201 tgaatagcgt cgagcatctc atagcgccga cggtattcag cccgtttttt actggcgatt
     4261 tcggcaatct cttttcgtgc tatctgtgct ggaaggcggt aatggcgttc agcatcacat
     4321 acgccgccaa ccgattccca gaaagcgttg taatcggcat ggatcttgcc ttctttatcg
     4381 cgataacgca ggctgcggta aatatgcgtt tcattgctga cggcaataat ctgctctacc
     4441 tgcaaacgtt gggcaaacag acaggccgct tccatcacga ggcgtttggg aaatagcccg
     4501 tggcaggctt tcgtcgcatt ctggatttcc tggtgtggaa tttcccattt tgcgccttgc
     4561 agtccgccaa taaacatcgt ccttttcccc tgatattcac acagggtaaa agtgagctct
     4621 gccagaggaa taccttcgct gttgcggaac aggatggtgc tgtcaccttc tttatccatt
     4681 gagatcatca tggtcagctc aagcgtgaac tgctcgccgt ttttgccttc cagcttcgcc
     4741 agttgcagcc cgggggtatt caaatataag ctgaattctt ccgccgacat acacccgcgg
     4801 agtaacgcat aatggtaacg taacgcctcc agcaattgct tacggctaag attcgccgca
     4861 aggtaagggc gatgtagacg tacaggcagt cgcggctggc gcgttaacaa cacattgaga
     4921 ttaggccagt gggaaagttc gttcatccac tcaacgctta aacgcggcat aatcaacgag
     4981 cgcagcaaaa atttctggcg aaaactacgg cgatgccaga atttacccgg ccgacactgt
     5041 cctcgtgcca gactaagaaa aagtgacagg ctgctgagag attcagatgg cgtaaaggtc
     5101 cgttcagtta gctgcgacat attcatgaaa tcaatggtta tacatgacgt cgatttaacc
     5161 attgcgtatc ttaaccaaac atcaatagtg tgattattaa cgtaaatttt agggttttgt
     5221 tgatatttcg ttgaagttaa tgacccggat tggcatatgg agtattcaga atatttatga
     5281 aaaagcggaa aaccgtgaag aagcgttacg ttattgcgat ggtgatagtc atcgccgggc
     5341 tgattacgtt atggagaatt cttaacgcac ccgtgccgac ttatcagacg ctgattgtgc
     5401 gccccggtga tttacagcaa agcgtgctgg cgaccggaaa gctggacgcg ctgcgtaagg
     5461 ttgacgtggg cgcgcaggtc agcggtcagt tgaaaacgct gtcggtggcg attggcgata
     5521 aagtaaaaaa agaccagctt ttaggggtta ttgatcctga acaggctgaa aaccagatca
     5581 aggaggtgga agcaacgctg atggagctac gcgcgcagcg gcagcaggcg gaagcggagc
     5641 tgaaactggc gcgggtgacg tattcccgtc agcaacgtct tgcacaaacg caagcggttt
     5701 cacagcagga tctcgataac gccgcgacgg agatggctgt gaaacaggcg caaattggca
     5761 ccattgacgc gcaaatcaag cgcaatcagg cctctctcga tacggctaaa accaatctcg
     5821 attacacccg catcgttgcc ccgatggccg gggaagtcac gcaaatcacc actctgcaag
     5881 gccagacggt gattgccgca caacaagcac cgaacattct gacgctggca gatatgagca
     5941 ccatgctggt aaaagcgcag gtttctgaag cggatgtaat ccacctgaag ccggggcaaa
     6001 aagcctggtt tacggtgctt ggcgatccac tgacgcgcta cgaggggcaa atcaaggatg
     6061 tgctaccgac gccggaaaag attaacgacg ctattttcta ttacgcccgt tttgaagtac
     6121 ccaaccccaa tggtttactg cggctggata tgaccgcgca agtgcatatt cagctcaccg
     6181 atgtgaaaaa tgtgctgacg atccctctgt cggcgttagg cgatccggtt ggcgataatc
     6241 gttataaagt caaattgttg cgtaatggtg aaacacgcga gcgtgaagtg acgattggcg
     6301 cacgtaacga taccgatgtt gagattgtca aagggctgga agcgggcgat gaagtggtga
     6361 ttggtgaggc caaaccagga gctgcgcaat gacgcctttg ctcgaattaa aggatattcg
     6421 tcgcagctat cctgccggtg atgagcaggt tgaggtgctg aagggcatca gcctcgatat
     6481 ttatgccggt gagatggtag cgattgtcgg tgcttcgggt tctggtaaat cgaccctgat
     6541 gaatattctc ggctgcctgg ataaggccac cagcggcacc tatcgcgtcg ccggtcagga
     6601 tgttgccacg ctggacgccg atgcgctggc gcaactgcgc cgcgagcatt tcggctttat
     6661 tttccagcgt taccatttgc tttcgcattt aaccgccgag cagaacgttg aagtacccgc
     6721 cgtctatgcc ggtcttgagt ggaaacagcg gctgcttcgc gcccaggagt tactgcaacg
     6781 actggggctg gaagaccgta cagagtatta cccggcacag ctttcgggtg gccagcaaca
     6841 gcgcgtcagt atcgcgcggg cattgatgaa cggcggtcag gtaattcttg ccgatgaacc
     6901 gaccggcgca ctggacagcc attctggcga agaggtgatg gcgatcctgc atcagctgcg
     6961 cgatcgcggg catacggtga ttatcgtcac acacgatccg caggttgctg ctcaggccga
     7021 gcgggtgatc gaaattcgcg acggcgaaat tgtgcgcaat cctcccgcca ttgaaaaagt
     7081 gaatgctact ggcggaacgg aacctgttgt caacacggcg tctggctggc ggcagtttgt
     7141 cagcggtttt aacgaggcgc tgacgatggc atggcgggcg ctggcagcga ataaaatgcg
     7201 tactttactg accatgctgg ggattattat cggtattgcg tcggtggttt ccattgtcgt
     7261 ggtgggcgac gccgccaaac aaatggtgct ggcggatatt cgttctattg gtacgaatac
     7321 tattgatgtc tatcccggga aagattttgg cgatgacgat ccgcaatatc agcaggcgct
     7381 gaagtacgac gacttaatcg ccatccaaaa acaaccgtgg gtcgcctcag ccacacctgc
     7441 cgtctcgcaa aacctgcgcc tgcgttataa caatgttgat gtggctgcca gtgccaatgg
     7501 cgtgagcggc gattatttta atgtctatgg catgactttc agtgaaggga acacctttaa
     7561 tcaggagcag ctgaacggtc gtgcgcaggt cgtggttctc gacagtaata ctcgccgcca
     7621 gcttttcccc cataaagcag atgtggttgg cgaggtgatt ctggttggca atatgcccgc
     7681 cagagtcatt ggtgtggcgg aagaaaaaca gtcgatgttt ggtagcagta aagtgctgcg
     7741 tgtctggctg ccatacagca cgatgtccgg gcgagttatg ggtcagtcgt ggctgaactc
     7801 cataactgtc agggtgaaag aaggctttga cagcgctgag gcggaacagc aactcacgcg
     7861 tttactttca ctgcgccacg gtaagaagga tttctttacc tggaacatgg atggcgtctt
     7921 gaaaaccgtt gaaaagacca cacgtacttt acaactgttt ctgacgctgg tggcggtgat
     7981 ttcgctggtg gtgggcggta ttggtgtaat gaatattatg ctggtgtcag tgaccgagcg
     8041 gacgcgggaa attggcattc gcatggctgt aggtgcgcga gcaagcgatg ttttgcaaca
     8101 gtttctgatc gaagccgtac tggtttgcct ggttggtggc gctttgggaa taacactgtc
     8161 actgttaatt gctttcacct tgcagctttt cttacccggc tgggagattg gtttttcacc
     8221 gttagcgctg ctgctggcgt ttctctgctc gacggtcacc gggattttat ttggctggtt
     8281 acccgcacga aatgcggcac gactggatcc agtagatgct ctggcacggg agtaattttt
     8341 gagataaaaa tgccagccga tcgggctggc attttgcctt taggatgtac acaatgagac
     8401 agaagagcta tgcgactgcc gcttctactt cgacgggcac aataacactg gcgtgattgc
     8461 cttttggccc ctggtggaca tcaaactgaa cggattgtcc agcttttagc gttctgtaac
     8521 catccatctg aatggtggaa taatgagcga aaatatcttc gccgccgcct tcagggcaga
     8581 tgaaaccaaa ccctttggca ttgttgaacc acttaacagt acccttttcc atgcttcgac
     8641 atccttcgca aatcttatac aagtaagatg gaataaaccg gggtcagaga gggggctgtt
     8701 caaaacctcg ccaactctag aaatacaatt tagagaatta gggcgagccg tcaagcattt
     8761 gacaggggcc agggggcagg tatgaatcaa aaatttgaag cagttaacgc tattgacagg
     8821 aatgtgacag atgtcgctga tgccaacgat agatgatagt tatctatcat gtggagtaga
     8881 ttggtcaggc aaataagctc ttgtcagcgg cagggcgttc tgccgataac cgtaaccgaa
     8941 gatgataact gacaatgggt aaaacgaacg actggctgga ctttgatcaa ctggcggaag
     9001 aaaaagttcg cgacgcgcta aaaccgccat ctatgtataa agtgatatta gtcaatgatg
     9061 attatactcc gatggagttt gttattgacg tgttacaaaa attcttttct tatgatgtag
     9121 aacgtgcaac gcaattgatg ctcgctgttc actaccaggg gaaggccatt tgcggagtct
     9181 ttaccgctga ggttgcagaa accaaagtgg cgatggtgaa caagtacgcg agggagaatg
     9241 agcatccatt gctgtgtacg ctagaaaaag cctgaatgca ggcataaaaa ttgggggagg
     9301 tgcctatgct caatcaagaa ctggaactca gtttaaatat ggctttcgcc agagcgcgcg
     9361 agcaccgtca tgagtttatg accgtcgagc acttgttact ggcgctgctc agtaacccat
     9421 ctgcccggga ggcgctggaa gcgtgttctg tagatttggt tgcgctccgt caggaactgg
     9481 aagcctttat tgaacaaacc acacccgttc tgcctgccag tgaagaggag cgcgacacac
     9541 agccgacgtt gagttttcag cgtgtactgc aacgtgcggt cttccatgtc cagtcctccg
     9601 gtcgcaatga ggttaccggt gcaaacgttc tggtcgctat ctttagcgaa caggagtcgc
     9661 aggcggcata tctgttgcgc aaacatgaag tcagccgtct cgatgtggtg aactttatct
     9721 ctcatggcac gcgtaaagac gagccgacac agtcttctga tcctggcagc cagccaaaca
     9781 gcgaagaaca agctggtggg gaggaacgta tggagaattt cacgacgaac ctgaatcagc
     9841 ttgcgcgagt gggcggaatc gacccactaa ttggtcgtga gaaggagctg gagcgtgcta
     9901 ttcaggttct ctgccgtcgc cgtaaaaaca acccgctgct ggtgggggag tctggtgtcg
     9961 gtaaaaccgc gattgcggag gggcttgcat ggcgaattgt tcagggcgat gtgccggaag
    10021 tgatggctga ctgtacgatt tactctctcg atatcggttc cctgttagcg ggcacaaaat
    10081 atcgcggcga ctttgaaaaa cgttttaaag cgttgctcaa gcagctggag caggacacta
    10141 acagcatcct gtttattgat gagatccaca ccattatcgg tgcgggtgca gcgtctggtg
    10201 gccaggtcga tgcggctaac ctgattaaac cgttgctctc cagcggtaaa atccgcgtaa
    10261 ttggttcgac aacctatcag gagttcagca acattttcga gaaagaccgt gctctggcgc
    10321 gtcgcttcca gaaaattgat attactgaac cgtcaatcga agaaactgtt caaatcatca
    10381 atggcctgaa accgaagtat gaagcgcacc acgacgtgcg ttataccgca aaagcggtgc
    10441 gtgcggcggt agagctggcg gtgaaataca ttaacgatcg tcatctgccg gataaagcga
    10501 ttgatgttat cgacgaagcg ggcgctcgcg cacgtctgat gccggtaagc aaacgcaaga
    10561 aaaccgttaa tgtggcggat attgaatccg tggtggcccg tattgcacgc attccagaga
    10621 agagtgtttc tcagagtgac cgcgataccc tgaaaaacct cggcgatcgc ctgaaaatgc
    10681 tggtcttcgg tcaggataaa gccattgagg cgctgactga agccattaag atggcgcgtg
    10741 caggtttagg tcacgaacat aaaccggtcg gttcgttcct gtttgccggc cctactgggg
    10801 tcgggaaaac agaggtgacg gtacagcttt cgaaagcgtt gggcattgag cttctgcgct
    10861 ttgatatgtc cgagtatatg gaacgccata ccgtcagccg tctgattggt gcgcctccgg
    10921 gatacgttgg ttttgatcag ggcggtttgc tgactgatgc ggtcatcaag catccacatg
    10981 cggtgctgct gctggacgaa atcgagaaag cgcacccgga cgtgttcaat attctgttgc
    11041 aggtgatgga taacggtacg ctgaccgata acaacggacg caaagcggac ttccgtaacg
    11101 tggtgctggt gatgaccact aatgccgggg tacgggaaac tgagcgcaaa tccattggtc
    11161 ttatccacca ggataacagc accgatgcga tggaagagat caagaagatc tttacaccgg
    11221 aattccgtaa ccgtctcgac aacattatct ggttcgatca tctgtcaacc gacgtgatcc
    11281 atcaggtggt ggataaattc atcgtcgagt tgcaggttca gttggatcag aaaggtgttt
    11341 ctctggaagt gagccaggaa gcgcgtaact ggctggccga gaaaggttac gaccgggcaa
    11401 tgggcgcacg tccgatggcg cgtgtcatcc aggacaacct gaaaaaaccg ctcgccaacg
    11461 aactgctgtt tggttcgctg gtggacggcg gtcaggtcac cgtcgcgctg gataaagaga
    11521 aaaatgagct gacttacgga ttccagagtg cacaaaagca caaggcggaa gcagcgcatt
    11581 aatctgattg tctggtaggt tggtgaagtc cgtaatctcg tcaggggtta cggacttttt
    11641 atttatgggg ggaggaggtt cagacccttt ttttgatgat gatggtaagt tattgataat
    11701 tagtgctgcg ggtaggtaag gataaaaaag ggtggcagca ggagattgag atggttttgc
    11761 tttattaaca acgggctaaa cgtgtagtat ttgagttcac tgccgtacag gcagcttaga
    11821 aattgccgcg gatcctgtct gccaataatg acaagttcac tgccgtacag gcagataaaa
    11881 tgcgaaaaaa aagcccgtac tttcgtacga gctcttcttt aaatatggcg gtgagggggg
    11941 gattcgaacc cccgatacgt tgccgtatac acactttcca ggcgtgctcc ttcagccact
    12001 cggacacctc accaaattgt ttttttgcct gacctcatgg ggggcaacgg ggcgctacta
    12061 tagggagttg gaataaaacg gtcaagaaga atttttatga taattattgt ttgctcatac
    12121 tgtaaacaag ttgtgcagta tatctacatc gagacaagtt acggacttat acttctaaag
    12181 tactccatac atatcacaaa ataaaaaggc cggctaaacc gaccttttac tcattctttc
    12241 tcttcgccca tcaggcggta aaacaatcag cgactacgga agacaatgcg gcctttgctc
    12301 aggtcgtacg gggtcagttc aacagtcact ttgtcgcccg tcaggatgcg gatgtagttt
    12361 ttgcgcattt taccggagat gtgtgcagta accacgtgac cgttttctaa ctctacgcgg
    12421 aacatggtat taggcaacgt ttcaagaacg gtaccttgca tttcaatatt gtcttctttg
    12481 gccatctaat cctctggggt atcactaccg taatttgaac cggcaagata atgccgaagt
    12541 tctgtaaata agtaaagatt tgcgcgctaa atcgcaacaa acaggttcgg cacattactc
    12601 cgaaaacaca cggctaagcc gcaccaaaag cgcaacgtat aagggagcgg tgagataaac
    12661 gatgggcgtt acctgacgcg aaaaattcct tatcggcagc ggggtaatga gcgtaaccaa
    12721 ctctgcgacc gcaattataa cactctgggg agaaatgtgc cgaaaacatt cattcttgtg
    12781 gtgaaaacaa gcatcgaggt acccagaaat tattcgacaa tcgtccgagg cgcatttgat
    12841 tgagataatt aaggtaatcc cggcggggaa tttcgcaggc accaagcgat gctgtgtgat
    12901 cgttaaggac ctggcagtcg ataagtttac cgccatgacg gataaattca tcacagaaga
    12961 ccagaagcgc cgttttggac gcattttcca tccggctgaa catggactcg ccacaaaata
    13021 gtgttccctg ggccacgccg tacataccgc cgacaagctc atcttcacgc cagacttcaa
    13081 tggagtgggc atgaccgagt tcgtgaaggc gatggtaggc ttcgaccacg ccacgcgtga
    13141 tccaggttcc ttcttcgcga tcgctggcac agccttcgat gacctgacca aaagcgtaat
    13201 tcatcgtgac acgatagggt gagcgtttat gaaatcgctt catactacgg ctgatatgca
    13261 gtgattctgg ccataacacc gcgcggggat cgggcgacca ccagaggatg gggtcgccag
    13321 gagaaaacca cgggaaaata ccacgctgat aagccattaa taggcgcgca gggctaagat
    13381 cgccccccag tgccagcagg ccgttaggct cacgtaatgc gccttccggg gaagggaagg
    13441 ctattgaatg gcgagaaagc tgaaccaggc gcatgaccgc aaaactccac gcaagtcgga
    13501 tcgttcaata atagcttaca aaccctgctt aaactggtaa taacgcccct gtctggcaag
    13561 cagttctgcg tgagtacctt gctcaataat ttgcccgttg tccatcacta ttatttgttg
    13621 gaaacgagag agcccgcgaa gtcgatgggt gaccattaac accgttttct cgcacatcat
    13681 ttctgcaagc aattcaagga tctgactttc ggttgtggca tctaagcctt ctgtaggttc
    13741 atccagcaat accagcggcg catcatgtaa cagcgcacgg gcgatagcca gacggcgcag
    13801 ttcaccaccg gagagctggc gtccgccttc acctaaccaa ctgttgagac ctgcatcctc
    13861 gagcagcttc tccagaccaa cgcgacgcaa gatctccgcc agagcctcat cactactacc
    13921 aggcgaggcg agtaacagat tatcacgcag cgtggcgcta aacagatgca ctcgctgggg
    13981 aacaacgctg atggtctgtc gtagagccgc ttcattcagg ctggctatgg gactatcgtt
    14041 aagcaaaatc tcgccctgtt gcgggtccca tgcgcgggtc agcagttgta acagtgttga
    14101 cttgccgcat ccggttcgcc cgagaatcgc aatatgttcc ccggcgttta cctgaagata
    14161 aatcccttta agtgcctgtt gggattgctc cggataagtg aactgaacat cccgtaatgt
    14221 cagcgaaacg cgatcggcaa cacgagtttg ggtatcaggg aaggtgactt tcggtttttg
    14281 atccgttaaa tcagtgatcc gtacggcaga ggcaatgact tgccccagat gctgaaatgc
    14341 acccgttact ggtgccagcg cttcaaacgc ggctaacgcg cagaagacaa acagggcaat
    14401 taacgcgccg ggttgagcat tgccgccaac gccgccagac gccatccaca gcatcaggat
    14461 caccgctaac gcgccaatga gcagcattat cgcttgcgac aatgcggtta gttcagattg
    14521 acggcgttgc gcttccagcc attgaatttc tgtattctct aattgcgtgc gataacgatc
    14581 gctggcacca aaaatggtca gctcagcttg cccttgcagc caggccgtca gttgttggcg
    14641 atactgcccg cgaagatgag tcagattttg cccggtgctt tttcccgcac gataaaacag
    14701 tggtggcatc aggaaaagcg tcagtaacat aatgccgccc agcgtaaagg cgagggtgaa
    14761 atcaaggaaa cttaacccga ttgtcaccac cataatcacc acaaaagcgc ctaccagcgg
    14821 cgagataacg cgcaggtaaa gatgatcgag cgtatcaaca tccgccacca cgcggttgag
    14881 taattcgccc tgacgatagc gcgccagtcc tgcaggggag aggggcagta atttgctgaa
    14941 ggtgtaaatg cgcagatgct gcaacacgcg gaaagtcgca tcgtgactta ccaggcgttc
    15001 aaaatagcgc ccggcagtac gggtgattgc tgcgccacgc acgcccgcag cgggtagcat
    15061 atagttgaag ctgtacagtc cggcaacccc cgcaaccgct gaggcggaga ggaaccagcc
    15121 cgaaagtgtc aacagaccga tactggcgag cagcgtgaca attgccagca cgataccaag
    15181 acttaacatc catttatgac gtttatacag tgccagatag ggtagcaaag cgcgcattta
    15241 aatctcctcc tgacgatggg ccagtaatgt ggcgaatggg ccaccagcca cacttaattc
    15301 cgcgtaacgt ccttgctcaa taatctgacc atcctgcatt acccaaatga catcccagtc
    15361 agcaagatct tctaactggt gggtgaccat taacgttgtc tggcgcagag aggcggcatt
    15421 cagcgcctcc attacgcgct gttcactgtg agcatcaagg ctggcagcgg gttcatccaa
    15481 cagtaatagc gaacagggat ttagtaacgc acgggccacc gccacgcgct gcgcctgccc
    15541 cacggaaagg cgggcagcct ggtcgccaac aggcgtatca acgccttgtg gcaggagcgg
    15601 tagaaactca ctgacccagg cgttatccag cgctgtttgt aactcttgtt cgctggcatc
    15661 aggtcgcgcc agtagtacgt tatcccgtaa tgttgctgcc ggtaattgtg ggttttgccc
    15721 aacccaggag agatgtttac gccatgattc cggtgataaa tcgcgtaatt ctatcccgtt
    15781 gattcgtagc gatccctgat atgagagaaa accagaaagc gcgttcaaca gtgaactttt
    15841 acctgaaccg ctgcgaccaa ccaacactgc tcgttggcct gctggcaaag taaaattcag
    15901 cggtccggcc agcgttttac cttccggcga cgtgataaac agatcctcgg cttcaatggt
    15961 caccggatcg gtcgatgcta attccgcttc accgcgctgc ggatgggcta gcggggtttc
    16021 cataaacgtt ttcaaactgt cagctgcacc aacagcctgg gctttagcat gataaaacgt
    16081 accgagatcg cgtaatggct ggaaaaactc tggcgcaagg atcagggcca gaaaacccgc
    16141 agccagcgtc acgccagtat cgtagtgacc aaaatccagc tcgccgaggt aggaaaaacc
    16201 aaagtagacc gccaccagag caatcgacag cgaggtaaaa aattcgagaa tgccggagga
    16261 taaaaacgcc agccgtagca cttccattgt ccgttggcgg aaatcttccg aagcagaacg
    16321 aatactttca atttcagctt caccacgacc aaaaatacgc aatgtttcca tgccgcgcag
    16381 gcgatcgagg aaatgcccac ttaagcgagc aagagcgaga aagttacgtc ggttagcatc
    16441 ggcagccccc attccaacca gcgccataaa taacggaatt agcggtgcag tgcccagcag
    16501 aatgagcgcc gcggcccagt tagaggggaa gatagccacc acaatcagca gcggcaccga
    16561 cactgccagc gccatttgcg gcaggtagcg tgcatagtaa tcatgcatat cgtcaatttg
    16621 ctcgagtacc agcgtcgccc agctccccgc aggtttaccc tgaatccacg ctggccctgc
    16681 ttgttgcaga cggtcgagaa cctgacggcg gatggcaaag cggatatgct gcccggcgtg
    16741 ataacccacc cgttcgcgta accagaccac ccatgcgcgc agtacaaagg tcagaaacag
    16801 taacgtaaag ggaagcagca gggcttcacg gggaatattc tccataatca tatgttgcag
    16861 aattcgcgcc atgaaccagg cctgggcaat gatcaatatg ccgctcacaa agcccagcag
    16921 acgagaaata ttcagccaac gttgggagat gacgctttgc tgttttaacc agcgggttaa
    16981 ttctttttga cgggatttat tcattgcacg cttagcaggt gagttatcag aattatttgc
    17041 agagcaatgt tacaacgggg aaaaaataaa ggcgacccat agtcgcatgg tgtcgccttc
    17101 tttacttttg ttactgattt gtaaaattat tttgcgtcag ctaaaccgtc gaggtagcgt
    17161 tccgcatcaa gagctgccat gcagcctgta ccagcagatg taatggcctg gcgataaatg
    17221 tgatccatca cgtcgcctgc ggcaaagacg ccagggatgc tggtctgggt ggcattacca
    17281 tgaatacccg actgtacttt gatgtagccg ttttccagtt ccagctgccc ttcgaaaatg
    17341 gcagtattcg ggctgtgacc gatagcaaca aacagaccgg caacgtcgag tgactcgata
    17401 ttatcggtgt tttgcgtatc gcgcagacga acgccagtga cgcccatctg atcgccggtc
    17461 acttcttcca gcgtacggtt ggtgtgcaga ataatgttgc cgttctccac tttatccatc
    17521 agacgcttaa tgaggatttt ttccgcacgg aaaccatcac ggcggtgaat cagatgaact
    17581 tccgaagcga tgttagacag atacagcgcc tcttcaaccg cggtattgcc gccgccgatg
    17641 accgcaactt tctggttgcg atagaagaaa ccgtcgcagg ttgcacaagc agaaactcca
    17701 cggcctttaa aggcttcttc agagggcagg ccgagatagc gtgcagaagc tccggtggca
    17761 ataatcagcg cgtcgcaagt gtattcgccg ctatcgccag tcagacggaa cggacgattc
    17821 tgcaaatcaa ctttgttgat gtgatcaaag atgatttcag tttcaaattt ggtggcatgt
    17881 tcgtgcatgc gctccattaa taacggaccg gtcagatcgt ttggatcgcc aggccagttt
    17941 tccacttccg tggtggtggt cagttggccg cctttttcca tgccggtaat cagcacaggt
    18001 tgcaggttgg cgcgcgccgc gtagacagca gcggtgtatc ccgccgggcc tgaacccagg
    18061 ataagcagtt tactgtgttt ggtcgtgccc atgagatccc catagttgtt ggcagacaat
    18121 ggcaggattg tagggaattt acagacgtaa aaaaagagta tgacgatttt gttaacaatt
    18181 tgtgcaatcg gcagcatcga taagcaggtc aaattctcac gtcattatca cctctgctac
    18241 ttaaatttcc cgctttataa gccgattaaa tgatgaataa acgcccctgt taatgaatat
    18301 ctggcatgtt gtactaaaaa tcgatgtttt gctttgacaa tcccctggtg ttttgcgaaa
    18361 acattcgagg aagaaaaaaa acagtattct tatatgcgca taaccatgca tgtaaatacc
    18421 atgtttaccg tgctagtgaa atctacgtat ggcgtggaca gacgccattc gtgatgtcga
    18481 tagctgccac aaggcaacgg tcttctcacc gtagacccag gcattgcgcg ccgtgaatct
    18541 tcatgatttc ggtctatcgt gacgggtagc gactctgaac agtgatgttt cagggtcaga
    18601 caggagtagg gaaggaatac agagagacaa taataatggt agatagcaag aagcgccctg
    18661 gcaaagatct cgaccgtatc gatcgtaaca ttcttaatga gttgcaaaag gatgggcgta
    18721 tttctaacgt cgagctttct aaacgtgtgg gactttcccc aacgccgtgc cttgagcgtg
    18781 tgcgtcggct ggaaagacaa gggtttattc agggctatac ggcgctgctg aacccccatt
    18841 atctggatgc atcacttctg gtattcgttg agattactct gaatcgtggc gcaccggatg
    18901 tgtttgaaca attcaatacc gctgtacaaa aacttgaaga aattcaggag tgtcatttag
    18961 tatccggtga tttcgactac ctgttgaaaa cacgcgtgcc ggatatgtct gcttaccgta
    19021 agttactggg ggaaaccctg ctgcgtctgc ctggcgtcaa tgacacacgg acatacgttg
    19081 ttatggaaga agtcaagcag agtaatcgtc tggttattaa gacgcgctaa cacggaacag
    19141 gtgcaaaatc ggcgtatttt gattacactc ctgttaatcc atacagcaac agtactgggg
    19201 taacctggta ctgttgtccg ttttagcatc gggcaggaaa agcctgtaac ctggagagcc
    19261 tttcttgagc caggaataca ctgaagacaa agaagtcaca ttgacaaagt taagtagcgg
    19321 ccgccgcctt ctggaggcgt tgctgatcct tattgtcctg tttgccgtct ggttgatggc
    19381 tgccttacta agctttaacc cttcggaccc cagctggtcg caaacggcct ggcatgaacc
    19441 tatccataat ttaggtggga tgcccggtgc gtggctggca gatacgctgt tctttatttt
    19501 tggcgtgatg gcttacacca ttcccgtcat tattgtcggc ggttgttggt ttgcctggcg
    19561 tcatcagtcc agcgacgaat acattgatta ttttgccgtt tcgctacgca tcattggcgt
    19621 tttggcgctc atccttacct cctgtggtct ggcggcaatc aacgctgacg atatctggta
    19681 ttttgcctcc ggtggcgtca ttggcagctt actaagcact acgctacaac cactgctaca
    19741 cagtagcggg ggaactattg cgctgctctg cgtttgggca gcgggcctga cgctgttcac
    19801 cggttggtca tgggtgacca ttgctgaaaa actcggcggc tggattttaa atattcttac
    19861 cttcgccagt aatcgtaccc gtcgcgatga tacctgggtc gatgaagatg agtatgaaga
    19921 cgacgaagag tatgaagatg aaaatcacgg caaacagcat gaatcacgcc gtgcccgtat
    19981 tcttcgcggc gcgctagcgc gtcgtaaacg gttggcggaa aaattcatta atccgatggg
    20041 gcggcaaaca gacgctgcgt tgttctccgg taagcggatg gatgatgacg aagagattac
    20101 ctacactgca cgcggtgtgg ctgccgaccc tgacgacgtc ctcttttcgg gcaatcgtgc
    20161 aacgcagcca gaatatgacg agtacgatcc attattaaac ggtgcgccaa ttaccgaacc
    20221 tgttgctgta gcagctgctg ctaccacggc gacacaaagc tgggctgcac cggttgaacc
    20281 tgtgactcag acgccgccag ttgcctctgt tgatgttcca cctgcgcaat ctacagtagc
    20341 ctggcagcct gtaccggggc cgcaaacggg agaaccggtt attgctcctg caccggaagg
    20401 ttacccacag cagccacaat atgcgcagcc tgcagtgcaa tataatgagc cgctgcaaca
    20461 accagtacag ccacagcagc cgtattatgc acctgcagct gaacaacctg cgcaacaacc
    20521 ttactacgct cctgcggcgg aacaacctgt tcagcaaccg tattacgcaa ctgcggcgga
    20581 acagcctgcg caacagccgt attacgcccc tgcgccagaa caagcggtgg caggtaacgc
    20641 ctggcaagcc gaagagcagc aatccacttt tgctccacag tctacatacc agactgagca
    20701 aacttatcag cagccagccg ctcaggaacc gttgtaccaa cagccgcaac ctgttgaaca
    20761 gcagcctgtt gtggagcctg aacccgttgt agaagagaca aaacccacgc gtccgccgct
    20821 ttactacttt gaagaagtgg aagagaagcg agcccgtgaa cgcgaacaac ttgcggcctg
    20881 gtatcaaccg attccagaac ctgttaaaga accagaaccg atcaaatctt cgctaaaagc
    20941 accttctgtt gcagcagtac ctccagtgga agccgctgcc gccgtttctc cgctggcatc
    21001 tggcgtgaaa aaagcgacac tggcgacggg ggctgccgca accgttgccg cgccagtctt
    21061 cagtctggca aatagcggtg gaccgcgtcc gcaggtcaaa gaggggattg gcccgcagtt
    21121 gccacgaccg aaacgcatcc gcgtgccaac tcgtcgtgaa ctggcgtctt acggtattaa
    21181 gctgccctca cagcgtgcgg cagaagaaaa agcccgtgaa gcccagcgta atcagtacga
    21241 ttctggcgat cagtacaacg atgatgaaat cgatgcgatg cagcaggatg aactggcacg
    21301 tcagttcgcc cagacgcagc agcaacgcta tggcgaacag tatcaacatg atgtgcccgt
    21361 gaacacagaa gatgcagatg ctgcggcaga ggcagaactg gctcgtcagt ttgctcaaac
    21421 tcaacaacaa cgttattccg gcgaacaacc ggctggggcg aatccgttct cgctggatga
    21481 ttttgaattt tcgccaatga aagcgttgct ggatgatggt ccacacgaac cgctgtttac
    21541 gccaattgtt gaacctgtac agcagccgca acaaccggta gcaccgcagc agcaatatca
    21601 gcagccgcaa caaccggttg caccgcagcc gcagtatcag cagccgcaac aaccggttgc
    21661 accgcagcag caatatcagc agccacaaca accggttgca cagcagccgc agtatcagca
    21721 gccacaacag ccggttacac agcagccgca gtatcagcag ccgcagcagc cggttgtacc
    21781 acagccgcaa tatcagcagc cgcaacagcc agttgcgcca cagccgcagg ataccctgct
    21841 tcatccgctg ttgatgcgta atggcgacag ccgtccgttg cataaaccga cgacgccact
    21901 gccttctctg gatttgctga caccgccgcc gagcgaagtg gagccggtag atacctttgc
    21961 gcttgaacaa atggcgcgcc tggtagaagc gcgtctggct gatttccgta ttaaagccga
    22021 tgttgtcaat tactctccgg ggccagttat cactcgcttt gaattgaacc tggcaccggg
    22081 cgtaaaagcg gcgcgcattt ctaacttgtc acgtgacctt gcccgttcac tttcgacggt
    22141 ggcggtgcgt gtcgttgaag ttattcctgg caaaccctat gtaggtctgg agttaccgaa
    22201 taaaaaacga caaaccgttt atctgcgcga ggttttggat aacgccaaat tccgcgataa
    22261 tccgtcgcca ttaaccgtgg tgctgggtaa agatatcgcc ggtgagccgg tggttgccga
    22321 tctggcgaaa atgccgcact tgttggttgc ggggactacc ggttccggta agtctgtcgg
    22381 ggtgaacgcg atgatcctga gcatgcttta taaagcacag ccagaagatg tgcgtttcat
    22441 catgatcgac ccgaaaatgc tggagctttc ggtttatgaa ggcattccgc acctgttaac
    22501 ggaagttgtt actgatatga aagatgccgc caacgcgctg cgctggtgtg ttaacgagat
    22561 ggagcgtcgt tataaactga tgtctgcgct gggtgtgcgt aatctggcgg gttataacga
    22621 aaaaattgct gaagccgatc gcatgatgcg tccgattcca gacccgtact ggaagccggg
    22681 tgatagtatg gatgcgcagc atccggtgct gaaaaaagaa ccgtacatag tggtgttggt
    22741 ggacgaattt gccgacctga tgatgacggt aggtaaaaaa gtggaagagc tgatagcacg
    22801 tctggcgcaa aaagctcgtg ccgcgggtat ccacctcgta ctggcaacgc agcgtccatc
    22861 ggttgatgtt attactggtc tgattaaagc gaatattccg acccgtatcg cctttaccgt
    22921 atccagtaag attgactcac gtaccattct tgatcaggct ggtgcggaat cactgctggg
    22981 tatgggggat atgctctact ctgggccgaa ctccactttg ccggtacgtg tccatggtgc
    23041 ttttgttcgc gatcaagaag ttcatgccgt ggtgcaggac tggaaagcgc gtggtcgccc
    23101 acagtatgtt gatggcatca cctccgacag cgaaagcgaa ggtggcgcgg gcggtttcga
    23161 tggcgctgaa gagctggatc cgttgttcga tcaggcggtg cagtttgtca ctgaaaaacg
    23221 caaagcatca atttctggcg tacagcgtca gttccgcatt ggttataacc gtgcagcgcg
    23281 tattatcgaa cagatggaag cgcaggggat tgtcagcgaa caggggcaca acggtaatcg
    23341 tgaagtgctg gccccaccgc cgtttgacta attaatgcat cgtaggccgg ataaggcgcg
    23401 gtagcgtcgc atccggcaat ctggtaactg aaaattcagt attttcttct ttcctcaagc
    23461 tgattattag cctggaatag agagtagagg gagctcccgg tcgggagtga cgtaatttga
    23521 ggaataatga tgaaaaaaat tgccatcacc tgtgcattac tctcaagctt agtagcaagc
    23581 agcgtttggg ctgatgccgc aagcgatctg aaaagccgcc tggataaagt cagcagcttc
    23641 cacgccagct tcacacaaaa agtgactgac ggtagcggcg cggcggtgca ggaaggtcag
    23701 ggcgatctgt gggtgaaacg tccaaactta ttcaactggc atatgactca acctgatgaa
    23761 agcattctgg tttctgacgg taaaacactg tggttctata acccgttcgt tgagcaagct
    23821 acggcaacct ggctgaaaga tgccaccggt aatacgccgt ttatgctgat tgcccgcaac
    23881 cagtccagcg actggcagca gtacaatatc aaacagaatg gcgatgactt tgttctgacg
    23941 ccgaaagcca gcaatggcaa tctgaagcag ttcaccatta acgtgggacg tgatggcaca
    24001 atccatcagt ttagcgcggt ggagcaggac gatcagcgca gcagttatca gctgaaatcc
    24061 cagcaaaatg gggctgtgga tgcagcgaaa tttaccttca ccccgccgca aggcgtcacg
    24121 gtagatgatc aacgtaagta gaggcacctg agtgagcaat ctgtcgctcg atttttcgga
    24181 taatactttt caacccctgg ccgcgcgtat gcggccagaa aatttagcac agtatatcgg
    24241 ccagcaacat ttgctggctg tggggaagcc gttgccgcgc gctatcgaag ccgggcatct
    24301 gcattctatg atcctctggg ggccgccggg taccggcaaa acaaccctcg ctgaagtgat
    24361 tgcccgctat gcgaacgctg atgtggaacg tatttctgcc gtcacctctg gcgtgaaaga
    24421 gattcgcgag gcgatcgaac gcgctcggca aaaccgcaat gcaggtcgcc gcactattct
    24481 ttttgttgac gaagttcacc gtttcaacaa aagccagcag gatgcatttc tgccacatat
    24541 tgaagacggc accatcactt ttattggcgc aaccactgaa aacccgtcgt ttgagcttaa
    24601 ttcggcactg ctttcccgtg cccgtgtcta tctgttgaaa tccctgagta cagaggatat
    24661 tgagcaagta ctaactcagg cgatggaaga caaaacccgt ggctatggtg gtcaggatat
    24721 tgttctgcca gatgaaacac gacgcgccat tgctgaactg gtgaatggcg acgcgcgccg
    24781 ggcgttaaat acgctggaaa tgatggcgga tatggccgaa gtcgatgata gcggtaagcg
    24841 ggtcctgaag cctgaattac tgaccgaaat cgccggtgaa cgtagcgccc gctttgataa
    24901 caaaggcgat cgcttttacg atctgatttc cgcattgcat aagtcggtac gtggtagcgc
    24961 acccgatgcg gcgctctact ggtatgcgcg aattattacc gccggtggcg atccgttata
    25021 tgttgcgcgt cgttgcctgg caattgcttc cgaagatgtc ggcaatgccg acccacgggc
    25081 gatgcaggtg gcaattgcgg cctgggattg ctttactcgc gttggcccgg cggaaggtga
    25141 acgcgccatt gctcaggcga ttgtttacct ggcctgcgcg ccaaaaagca acgctgtcta
    25201 cactgcgttt aaagccgcgc tggccgatgc tcgcgaacgt ccggattatg acgtgccggt
    25261 tcatttgcgt aatgcgccga cgaaattaat gaaggaaatg ggctacgggc aggaatatcg
    25321 ttacgctcat gatgaagcaa acgcttatgc tgccggtgag gtttacttcc cgccggaaat
    25381 agcacaaaca cgctattatt tcccgacaaa caggggcctt gaaggcaaga ttggcgaaaa
    25441 gctcgcctgg ctggctgaac aggatcaaaa tagccccata aaacgctacc gttaatgtta
    25501 tcgttgcggt aatgttgtta atgtatccct gtggtcgcag gctgtggcca catctcccat
    25561 ttaattcgat aagcacagga taagcatgct cgatcccaat ctgctgcgta atgagccaga
    25621 cgcagtcgct gaaaaactgg cacgccgggg ctttaagctg gatgtagata agctgggcgc
    25681 tcttgaggag cgtcgtaaag tattgcaggt caaaacggaa aacctgcaag cggagcgtaa
    25741 ctcccgatcg aaatccattg gccaggcgaa agcgcgcggg gaagatatcg agcctttacg
    25801 tctggaagtg aacaaactgg gcgaagagct ggatgcagca aaagccgagc tggatgcttt
    25861 acaggctgaa attcgcgata tcgcgctaac catccctaac ctgcctgcag atgaagtgcc
    25921 ggtaggtaaa gacgaaaatg acaacgttga agtcagtcgc tggggcaccc cgcgtgagtt
    25981 tgactttgaa gttcgtgacc atgtgacgct gggtgaaatg cactctggcc tcgactttgc
    26041 agccgcagtt aagttgactg gttcccgctt tgtggtaatg aaagggcaga ttgctcgcat
    26101 gcaccgcgca ctgtcgcagt ttatgctgga tctgcatacc gaacagcatg gctacagtga
    26161 gaactatgtt ccgtacctgg ttaaccagga cacgctgtac ggtacgggtc agctgccgaa
    26221 atttgctggc gatctgttcc atactcgtcc gctggaagaa gaagcagaca ccagtaacta
    26281 tgcgctgatc ccaacggcag aagttccgct gaccaacctg gtacgcggtg aaatcatcga
    26341 tgaagatgat ctgccaatta agatgaccgc ccacacccca tgtttccgtt ctgaagctgg
    26401 ttcatatggt cgtgacactc gtggtctgat ccgtatgcac cagttcgaca aagttgaaat
    26461 ggtgcagatc gtgcgcccgg aagactcaat ggcggcgctg gaagagatga ccggtcatgc
    26521 ggaaaaagtc ctgcagctgc tgggcctgcc gtaccgtaaa atcatccttt gtaccggcga
    26581 catgggcttt ggcgcttgca aaacttatga cctggaagta tggatcccgg cacagaacac
    26641 ctaccgcgag atctcttcct gctccaacgt ttgggatttc caggcacgtc gtatgcaggc
    26701 acgttgccgc agcaagtcgg acaagaaaac ccgtctggtt cataccctga acggttctgg
    26761 tcttgctgtt ggtcgtacgc ttgttgcagt aatggaaaac tatcagcagg ctgatggtcg
    26821 tattgaagta ccagaagttc tgcgtccgta tatgaatgga ctggaatata ttggctaata
    26881 cccaattttt ctgaatctaa aaagcgcctg cgggcgcttt aagtagaggt ttaatcattt
    26941 gaaaataaat ggattttatt tttaagtgtc catataacgt ccatctttga atgcaaaaag
    27001 cccacagctt ctatgctgtg ggctttgttt tttggtgtcc tcatgagtga gggaaccaaa
    27061 aagaaaaccc gcagttttta cgctgcgggc ttgttgttca cgtcaactgg aaatagggtg
    27121 ccttttcgac ctttaccctg gcaaccgatt gacggggaag ttgccttccc cgtcgcggtt
    27181 tccttactgc ttacactgta agaacgccgc aaactccgct ccccagaaac tcatccgtat
    27241 ttcacacagc gaaccgtgca gcatccagat gatgaggatt gccgtcacgc agaatgtgat
    27301 ggccgtaagc gatttttgcg acatagcgct tgctcctttt tcggggaggc gctaacctat
    27361 cacttgctga gggtagatgg ttagggcctc gggttaacgt taaagttgac tcggggcctt
    27421 tccacatctg gccttcgggt attccctccg accatcagcc gaaaggcacc cgcacgtaat
    27481 ctatcgcttt tttgttactc cggcaattct gcctgttaat tctgagataa aggcaaactc
    27541 atctgattgt ttcccctgtg tgaagctggc agatcatgcc acgggatacc ttctgaagag
    27601 tgaacgccgg aggcgtgttt tgatgtgaat ttatggaaag cttccagtgt tgagaagcat
    27661 acgccgcatt ccagattgtt acactggtaa tacttttgcc gcacggtgtt tgaatcattt
    27721 tccggacgac tggtgcggat acgggcagat gcgccacaaa gcggacaacg gaacatagcg
    27781 acctccctta acgtggtgct gcctattcta agttgctcac tctgtttccg ctatccattc
    27841 cgggattttt gcctcaagct caagctgcgt ggtaaaaccg ctgttatcaa tggtgtgctc
    27901 ggcttttgca atgatccagt cctgattatc aatctcgctt ttaaatcctg ttaccgtgcc
    27961 atgcatttcg gggtagagtt ctgcacgtcc acgcgccagc gtgatggaga atgatgcggc
    28021 tccgcgttgt agttgctgcc actttgccgc cgctgcgcgt cttgctgcct gctcgttctg
    28081 ataagtcttg cgtaacacaa acacattgcc ttccgcgcct tccatataat caccttcgcg
    28141 gctgctgctt ttctcctttt tgggttttgg cggtttacgg cgtttcacgc tgactttttt
    28201 ctttttcccg taattaagat caagccagta agcgcgtacc cccgtatacg cttcgcggtc
    28261 agcaatgcgg aactgatggc gatcgccgct gctgcgtgtg atggcaaacg atggcaacgg
    28321 ctggccctgt gcgttcacgc caccgccggg catgatgaat aacagattac cgctttttac
    28381 cgtggtgatt gcgcccagca tttccgccat gcgcgtaagg aaggacatgt cgctttcttc
    28441 ggtctggtcg gcgtggtcga tttcgatatc catcagcatt tcgctgattt gcggtttcag
    28501 accataccga tgagcgatgg cggataccac acgctcaacg gtcacatcat gccaggacac
    28561 ctcacgttta acgttaaatt catcccgaaa atctgcgctt ctggctgaaa cagtcagcct
    28621 gtccggcggt ccttcgtgag cgatttcatc aacaatgtaa gtgccttttt ctgtcagcgg
    28681 ttctcctttc cagccaatga gaaccgtcag gcgcgcgccc cgtggcggta gctgcaactg
    28741 accatccgca tcatccagcg tgatggtgag ctggtccgcc tcaaatcccc ggttgtcggt
    28801 cagtgacagg ctcatcaggc gctctgccac gcctgacagc gttttaccct ccgcgagaat
    28861 atcaaaatcc ggcattttca cggggtctgt gccctgactg agcaattgca tggtggtgtc
    28921 ggtcatctgc tccctccctg tgcggcatgg tcgcatgtgc gtgcggaggg ggttactgct
    28981 ttttgttgtc gccgtggcgg gagaacggcg caggggtgag attacgcgcg tggtgggtga
    29041 tgattgttgc cgaatcattt aacggataca aggggctgaa gctatgagtg aaactcgttt
    29101 tcatggtgcc cgtgtcacgg aaagtaccga cctggtaaca gcgattaatg atgttgattc
    29161 cagcgttatc ggtatcgtgg caacggcgga tgatgcggat gcggagctgt tcccgctgaa
    29221 caagcccaca ctgctgaccc gcgtcaatga cgtgctggga aaatgcggga ctacggggac
    29281 gctttatcgt gcgcttaagg ctatcgcaga ccaggtgagc acaaaagtga tcgtcgttcg
    29341 cgtggctgaa cacaaagaag aaggcggtag gacgcaggat caactggtta tcggtggttc
    29401 tgaatctgac ggcagctata cggggatgta tgcgctgctt gttgcagagc aggatgaaag
    29461 catcggatac cgtccgcgta ttctggccgc gccggagctg gacacggagg cggtgacaaa
    29521 atccctgtgc gtgattgcgg gtaaactgcg cgcgtttgtg tatgccacat gtcatggttg
    29581 taacacgatg gctgaggcga ttacctaccg ccagaaattc aacgaacgtg aggtgatgct
    29641 cttatggcct gacttcatcg cctacaaccc gaaaagtggc aaaaacgaaa cgttccccgc
    29701 gcctgcttat gcgtgcggcc ttcgtgcgta cattgaccat gagcagggct ggcacaaatc
    29761 gctgtccaac gttccggtta aaaatgtgct ggggatgtcg aggcatgtgt tctggtcgtt
    29821 acaggccgaa gacagtgatg ccaacagcct caacaacaaa gaaatcacga ccattattcg
    29881 tcgtaacggg ttccgcttct ggggcaaccg cacaccggaa acgaacgcct acatctttga
    29941 ggtgtatacc cgaaccgcac aggtgctggc tgattcaatt gcggaagcgc agtttgaaac
    30001 catcgacagt ccactgacgc ctgcgaacgt gaaggatgtt atcagtgcca tcagggcaaa
    30061 attggattcg ctggttactg ccgggaaact gattggcgcg gagtgctggt atgacgtggt
    30121 ggataacggc accacggatt tacgtcaggg gcgtgtgcgt attcgctaca aatatacgcc
    30181 cgttcccccg ctggaagaca tggagcttta ccagacgttt actgatgaat tctttggtcc
    30241 cgcatttgcg gtgctgggag gtgcctgatg gctgtaccaa aacatcttcg cttttttacg
    30301 ttgtttgtgg atggtgaaaa cgaagtgggt aaagtgacat ccgtcacgcc gcccaaactg
    30361 acgcgcaaaa ccgacagcta tcgtggtggt ggcatgatgg gagcagtaag tattgatctc
    30421 ggtctggacg actccgcgct tgatgcgagc tttgtcatgg ggggagctgt tcgtgcactg
    30481 ttccttaagt atggcggcac gattgacggc acgctgctgc gttttgcggg tgaatattac
    30541 accgatgcag aaagcgatct gtatgaaatc gagatgcgcg ggcgtgtgac ggaaattgat
    30601 atgggggagg ccaaacaggg cgaagccaca tcacacactt acgctgtcaa aaacacctac
    30661 tacaagctga gcgttaacga tcgcccgctg tgggaaatcg acctgttgaa ccacatctac
    30721 cggaaggacg gcaaggacat tgtgcctgac cgcattcgtt ccgcgcttgg gcttggctga
    30781 taagtaatat gcaggcggcg cagtgcgtcg cctctgactg aaaaggagac aactgatgaa
    30841 agatatcgat actgaaaccc ggaataacac cgtagcggat gatgtgacgt caggtgagga
    30901 tatggctgtc gaacgtggtg taaaactttc ccggccaatt gagcgtggtg ccgaaaaaat
    30961 cacatatgtg gagatcaccg gggctattga gcaggcggga tccctgcgtg gtctgtcgct
    31021 gtctgatgtg ctgaatctga aagcggatac catgttcacg ctgttgcctc gcgtgacctc
    31081 gccacgactg gatgaagtga tgattaaaaa aatgtcgtca cgcgatttta ttcagttgtg
    31141 cgctgtggct gtaaatttta tgagcgagcc agactctggc gcgaagagcg tgcaggagac
    31201 ggcagcgtaa tcaccctggt gtgctttgag cacatcgaag atctggtggc ggatattgcc
    31261 gccattttca actggtcgcc cgccgaaatc ttcatgatga cgcccggcga agtggttagc
    31321 tggcgtgagc gggcggcact tcgcagcggg aatgcagata atgaagactc ttgacatccg
    31381 ggtcgctttc agcgccgttg acaggctgac ccggcctgcc gaaaacgccc gccgcctgat
    31441 ggggcagttt ggtgactcca ttcagcgaac gcagggggcg atcaaaaatc tcgagcgtca
    31501 ggcgcgttca tttgagcgcg cccgcgacgc tgtcagtaaa gcggatgcgg gtatcgtgaa
    31561 agcacgacgc cagcttaacg cccttaatca gttacaacgc acgggtacag tgctcagcga
    31621 aaaacaacaa aagctgatgc agcagttaag cacccggctt gaacgcctga atgaatcgcg
    31681 cacacgggaa attcagaaaa tgcgggagct tggcggagaa ctgaaacgcc acggcatttc
    31741 cctgacaggc agcgataaca ccatccagca ggccatcaga cgcaccgaac aatacaacaa
    31801 ccagcttgaa cgcgaacggc aggcgcttgc gcgtgtaacg caggctcgtg agcggtattc
    31861 gcgcgcgcag gaaaccgcgg gaaaactgaa aacaggtggt gcgctggcaa ttggtgcggc
    31921 agcggcgggc ggctatgctg ccgggcgttt tttgcagccc gcgatcgggt tcggcaaaga
    31981 gatgtcccgc gttcaggcgc tgacgcgaat cgacaaaaac agcccgcagt ttaaggcgct
    32041 gcgtgagcag gcgttaaaac ttggctctga aacacagttt actgcgagtg atgccgccag
    32101 tgggcagagc tttctggcaa tggctggttt tactccgcag gccattcagg ccgcattgcc
    32161 cggtgttctt aatatggcgc tggcaggtgg cgtcgaactc ggcgagacgg ctgatatagg
    32221 ctccaatatc ctcacacagt tcaacctgac agccgatcaa atggaccggg ttggcgatac
    32281 gctgacagcg gcattcaccc ggaccaatac tgatttacgc gcgctgggcg aaaccatgaa
    32341 gtataccggt ccggttgccg caaaacttgg tatcagtctt gaagaagcgg cagccatggc
    32401 cgggatgctt gccaataatg gtcttcgtgg aagcgatgct ggtacggcca tgcgcgcaag
    32461 tctgtcccgc cttgcatcac cgccaaaagc tgcggctgat gcgctgaaag agctgggggt
    32521 gtcagttgct gacgccagag gcaaaatgcg cccgatggag gatgtgctgc ttgatctcta
    32581 taaggcgaca caaaaatacg gacaggtgga ccaggtttcc ttcttcaagg acatcgccgg
    32641 agaagaggcg ttcgttggtt tgcagacgct tgttgcggcg gctggttcag gagagctgca
    32701 aaaactgacc agagaattgc agggggcaag gggagaggcc gatcgcgttg caaaagtaat
    32761 ggccgataat cttgatgggg acctgaaaaa tctcgacagc gcatgggaag gtcttcgtat
    32821 tcgcatcagt gatctggttg acggtccgct gcgttctgtc acgcagtggc tcacgcgggt
    32881 gcttgaaaaa atcacctcgc tggcgcaggc ccatccggta ctgacgcgcc agctactgat
    32941 agcaggcggt gcgttgctgg caatgactgc aacggttggc tcgttgtcgc tggctattgg
    33001 tgtgcttgct ggcccgctgg caaaactgcg tcttggcttt tccctcctga ccggttcaat
    33061 gaatgctgtc agactcctgc cagcactatg gggaatggtg acgggttccg tttcgttact
    33121 ggggggcgct atcggggcgt tgttcagtcc ggtcggcctt atcgtggctg cgcttgccgg
    33181 agctgccgtt ctcatctgga aatactggga tcccatcagg gcattttttg ccggggtgtt
    33241 cagcgggatt atggaaaggc tgaccccgtt gcgcgaaacc tttgaacggt ttggtcctgt
    33301 ttttgacgca atcgggagtg ggatcagcca ggtgtttaac tggtttaaat cgctgctgtc
    33361 tccgatggag tccagcaagg aaactctgga taaatgtacc agtgctggcg agatattcgg
    33421 taacgttctt ggcggtgcgt tacaacttgt tctgacacct gcaaaaatgt tgctggatac
    33481 gctggcgtgg atacttgaaa agcttggtgt gcttccggat gaagcggaaa gggcgcgcaa
    33541 gaaaatcgaa gacgcacagc gtgcggccat tcttcaggac aaggttgcct tgcttcaggg
    33601 ggacctggcg aaaatcaatc cgccgaagcc tgtggaaaat ggcaatggca ccggaggtga
    33661 taaccccaaa gacaataaac cgctcacaga cagcaatacc ggtacgctgc gcagactcag
    33721 caaaattgct gataacacag gtaagctggt tgaggagacg aaaaaacgca ttggccccgg
    33781 cgatattgtc tttaaaaacc tgccccgagc acttgctgtt cgtggggagt ggcaggagcg
    33841 gaagattgcg caggtcagta agcctgcccc cgcaattaat atcacacccg tggtcccggc
    33901 tccgctgcct ccggcgctgg tccctgttgt tgcggccagc tcccgcccgg tggcggaggc
    33961 tatacgatct ccagtggcat cagttcctgt aacttcccgt aaccgggagc ctgttgcctc
    34021 cggatttggt ggtgaaattc atgttcatct gcataacgtt gttacgcaga atccccgcga
    34081 actggcgaaa ctggtcggtg aaatggtcag ggcagaaatg gaacggcgcg cccgtgccgg
    34141 gcgtggcagt ttttacgata aagattgagg agtcatggcc atgatgatga tctacggcat
    34201 gtttgttttt gagctgcgca cgctgccgca tcagcagtta cagcaaaaca aaagctggcg
    34261 gcatgtgaaa aatgaacgcg ttaaccgttc agcaagctgg cagtatatcg gtgcaggtga
    34321 tgatcgcatc gttctttctg gtgtgcttta tcctgaaatt acaggtggcg aagtgtcgct
    34381 gtcgctgctg accacgcagg cgtatacagg acgaccctgg cctttgattg atggcgtcgg
    34441 gcagatttac ggcatgtatg tcctgactga aacgaatacg acccgctccg agtttgatcg
    34501 ctacggtaag gcgaaaaaga tagaattttc actgactctt gaacgctgtg atgaggattt
    34561 gcgggagcgc ctgcaatcct catcgttcag tgatatgctg tccggcttca aagataaggt
    34621 gacatcatct cttaacagcg cggccagttc agttaaaggg ctgttctgat ttaacacaaa
    34681 aaccgctaat ggtcagatta gcggttttca ttttcctgag tctgcccggt tgtttcttca
    34741 gtctgtatat cgcctacagg gtgataacga taaatcgtcg atgtgccaat gccgtaaatt
    34801 attgccagtt gttttctgtc gtgcccgttt ttgattagcc ttgctatttg ctcatgctgt
    34861 tcttttgtca gcttcggtcg acgtccgcct gtgcgccccc ttgcgcgcgc tgccgccagc
    34921 ccggccagtg tacgttcaac aattaattca cgttccattt cagccagggc acccatcacg
    34981 tggaagaaaa aacgccccat tggagaagat gtgtctatgc tgtcggtcag actgcgaaaa
    35041 ttaatccctc gctcccgtag ttccccgacg agagaaatca gatgtttcat gcttcgcccg
    35101 aggcgatcca gtttccagac aaccagcgtg tcaccttttt gaaggcgctt taaagcgcgt
    35161 tttaatcccg gtcggtctgt ctttgtcccg cttaatttat cttcaaatat ttgttcacat
    35221 cctgcacaaa caagagcgtt tcgttgcagg tctgtattct ggtcatttgt tgataccctt
    35281 acatagccaa tcagcacact gaatctcccg tccaaaagcg caaatcatgc catgcaggcc
    35341 agaaacggcc attat
//
LOCUS       DAFGPF010000047        34269 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFGPF010000047 DAFGPF010000000
VERSION     DAFGPF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34269
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.047"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            74..841
                     /locus_tag="LSX49_002492"
     CDS             74..841
                     /locus_tag="LSX49_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBL7168891.1"
                     /translation="MAETSSTTAGAQTLLRGLAVLNAVYNGCHDLKSIGEFTGTTRST
                     THRLVTVLVEQRYLRHVPTQGYQLGAKLIEFGARALESTSLYEIAQPVLQRLARYTLD
                     TVHLGIVEGDEVLYLEKINSQRGLEMRSRPGHRMPLAITGIGKALILNRTEEEWRTLF
                     KTCGDETKLGAFIQNMRRYAASGFAFDLEENEPTIRCVAAPVYNARDEIVAAISVAST
                     TTYMSLARLEELAPYVKSCAEEISAELGWGKHVRKDK"
     gene            865..1869
                     /locus_tag="LSX49_002493"
     CDS             865..1869
                     /locus_tag="LSX49_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HBL7168892.1"
                     /translation="MPGAPSFIALDWGTSSLRAWRFGESPNPQEKREFPWGIMKLPSQ
                     AATREDAFHDTFLRVCGDWLAQTPCPVLACGMLGSAQGWQPAAYLPCPVTLEGLAKQL
                     TPVIHQQQTMLHIIPGVIKEGEMPEVMRGEETQIFGAISMEPSLQNAIHQGMPVLIGL
                     PGTHAKWAVVENNTITDFRTFMTGELFDVLSRHSILGATMHPGDELHWDAFTHGLTAA
                     QEHHQTGLLSTLFSTRSRLLTSNLTSSSQGDYLSGLLIGHELCGLASSLLRDLPATTP
                     IALIGSANLNSRYSQAFSHVFPDRQIHAIPNATEQGLWRIAHAAGLLSTNARECTHAI
                     "
     gene            1859..2488
                     /locus_tag="LSX49_002494"
     CDS             1859..2488
                     /locus_tag="LSX49_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001116470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HBL7168893.1"
                     /translation="MPFNTLLQKTGLVAILRGVKPDEIVAIGEKLYAAGFRLIEIPMN
                     SPEALQSISLLRDALPKDCLVGAGTVLSVEQVVAVKEAGGQIIVMPHCDTAVIRRARA
                     LGMYCAPGVATPTEAFTAIEHGANAIKLFPAEQITPEVTKAWRAVIPQSVPMLPVGGI
                     TPETMARYLSHGANGFGLGSALYHPGMTPEQVYENAVLFMNAWNNLNSN"
     gene            2513..3487
                     /locus_tag="LSX49_002495"
     CDS             2513..3487
                     /locus_tag="LSX49_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HBL7168894.1"
                     /translation="MIKHLTLPKKMAAMVLLAGAALSIAPVQAASWPTKQIELVVPYA
                     AGGGTDLVARAFADAAKNHLPVSIGVINKPGGGGAIGLSEIAAARPGGYKIGLGTVEL
                     TTLPSLGMVRFKTSDFKPIARLNADPAAITVRADAPWNSYEEFMTYAKANPGKVRIGN
                     SGTGAIWHLAAAALEDKTGAKFSHVPYDGAAPAITGLLGGHIEAVSVSPGEVINHVKG
                     GKLKTLVVMADERMKTMPDVPTLKEKGVDLSIGTWRGLIVSQKTPQDVVDVLAKAAKE
                     TAEEPAFQDALQKLNLNYAWLDAASFQTQISEQEKYFDELLTRLGLKK"
     gene            3504..4010
                     /locus_tag="LSX49_002496"
     CDS             3504..4010
                     /locus_tag="LSX49_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001596577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HBL7168895.1"
                     /translation="MNTKQSVAQLAVPHRKRLSSTMVVALLLCVVAGAVMINAADFPA
                     TAIETDPGASAFPTFYACALIVLAVLLVIRDLLQAKPASCANAQEKPAFRKTATGIAA
                     TAFYIVAMSYCGYLITTPVFLIVIMTLMGYRRWVLTPGIALLLTAILWLLFVEALQVP
                     LPVGTFFE"
     gene            4023..5513
                     /locus_tag="LSX49_002497"
     CDS             4023..5513
                     /locus_tag="LSX49_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HBL7168896.1"
                     /translation="MFESELLTQGFSTLLNNPQALLFATFGVMLGIVIGALPGLTATM
                     GVAILLPFTYGMEPVSGLLMICGVFFGGVYGGSITAILLKIPGTPAAAATAIDGYELT
                     KQGKAGLALSAATFSSFSGGTLSIIVLMFLSPVLASWALKFSASESFALATFGLSIIA
                     SISGESLIKGLIAGVGGLLIATIGLDPMGGFPRFTGGFVELMNVPFIPVMIGLFAASE
                     AFRSMEQNQQIRQGAKVAIGSLLLPWQTLRRIALTILRSSGLGVFIGMIPGAGADIAA
                     FVAYNETRRFSKTPENFGKGEIKAVASCEAGANGCTGGALLPMLTLGIPGDAVTAIML
                     GALTLQGMQPGPLMFTDHGDMVYTLFVGMIFCYFMLLVLGLLSLKVIGNVVKIPGNIL
                     TPMILALCVVGTYALNNSLFDVGIMLIAGVVGYFMQKGGYPASPVVLALIMGPMAESN
                     FRRALSLSGGSLDFLYTRPITLALLTLAAFTLLTPIIRKIMRLRRQ"
     gene            complement(5548..6312)
                     /gene="udp"
                     /locus_tag="LSX49_002498"
     CDS             complement(5548..6312)
                     /gene="udp"
                     /locus_tag="LSX49_002498"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001593007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HBL7168897.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLLK"
     gene            6574..7383
                     /locus_tag="LSX49_002499"
     CDS             6574..7383
                     /locus_tag="LSX49_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBL7168898.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLGGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPVLGLYGGQDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAEHAFNADYRPSYHAESAKDGWQRMLEWFTQYGVKK"
     gene            7640..8308
                     /locus_tag="LSX49_002500"
     CDS             7640..8308
                     /locus_tag="LSX49_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL7168899.1"
                     /translation="MTQSIFQAQPFELPFDPRTTALVMIDMQRDFVEAGGFGEALGND
                     VSRVRTAIAPCTEVLAAARQKGIMVIHTREGHRADLSDCPPAKLTRGGKTFIGEPGPM
                     GRILVRGEAGHDIIPELYPVAGEPVIDKPGKGAFYQTDLHLILQNHGIKTLIVCGVTT
                     EVCVTTTVREANDRGYECIIPEDCVGSYFPEFQKYALEMIKAQGAIFGWVTDSKAIIA
                     GLEG"
     gene            8314..9174
                     /locus_tag="LSX49_002501"
     CDS             8314..9174
                     /locus_tag="LSX49_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001374637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HBL7168900.1"
                     /translation="MVQVTLCASSLGYLFPQDETQDLRLHSAFKHAVNLYSDAGTFIT
                     LLCAQTYLNLPDAARVWLPECWDWRREIAHSDPIQLTPGLLRTPRFCVALDNATLWQS
                     PFVGGMLTLEAFPLVFQHYPTMASQRLLFCLEHNVQSTLHLPDSLTHQGLAIMEHPDA
                     LERQVPQLIGFGKGLTPDGDDYLLGYLAALWLWQLPAPLADHQYRLQQAIDQHAHNTT
                     DISRHYLERALQGHFSEPICQLLAQLVGSASAMTIASCAEQVMQFGATSGVDCLAGML
                     HGFRTLNTMN"
     gene            9269..10828
                     /gene="fdrA"
                     /locus_tag="LSX49_002502"
     CDS             9269..10828
                     /gene="fdrA"
                     /locus_tag="LSX49_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HBL7168901.1"
                     /translation="MKVKYKVFSNLYQDSVSLMQISAQISKLPGIQQASVVMGTPNNL
                     EQLRDAGLGNEINASPNDLVIAVMGEEDICNEALILAQQRLTSKPDDETDSGIKTPEK
                     VSLEMALEAEPEANLALISVPGDYAAAEAIKALNLGMNVMMFSDNVSIVQEKSIKTLA
                     RERQRIVMGPDCGTAIVNGIPLGFANVVKRGAIGVIGASGTGLQEVTCRIDQLGAGIS
                     QALGTGGHDLSKEIGGISMLFALDALAQDDETRVIVLISKPPSPIVARTILERAEACG
                     KPVVVNFLGANPHDLARPNITAATTLASAADIAVALLNAQPLPAVETDVPCDDLTMLQ
                     NACQRLPAHRQAIRGVFAGGTFCYEAQLICQQKGFSAASNTPVAGNRALANIWQSEDH
                     TLIDMGDDDFTRGKPHPMIDPTLRNQRLLNELNDSHTAVVLFDLVLGYGASTTPASEL
                     LDQLSHIDMNNAPLLIAHVCGTEADPQIRSQQISALQNAGVIIASSNAQAALWASTVA
                     QTQLQKKGLNA"
     gene            10825..12249
                     /locus_tag="LSX49_002503"
     CDS             10825..12249
                     /locus_tag="LSX49_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HBL7168902.1"
                     /translation="MNTLFNQPLKVVNAGLHSFADNIQHAGGSAIALNWQPPAQGDID
                     AGLDLASLLRHPLVENANQIAMARYLEAQPVLVDVMLAKEAIPAMAEQKRILHSGPPI
                     AWEEMCGPVKGAIIGAMLYEGWATSQQDAENQINAGEIDLAPCHHYHAVGPMAGIISP
                     SMPLWVVENKTNGHRTFSNFNEGLGKVLRFGANNDEVLNRLAWMRDELTPAMKAAIAQ
                     HGELELKPLMAQALHMGDEVHNRNAAATGLLIKRLLPALLACSLPQEHIQRVVAFITG
                     NDHFFLNLSMAACKAMMDAAANVPFSSMVTVMARNGVNFGIRISGTGDRWFQAPANAV
                     EGLFFPGFGVDDAAADLGDSAITETAGVGGFAMASSPAIVKFVGGTPADATNNSRRMQ
                     AITLGGNPAFTLPALNFAPTAAGIDARKVTDRGILPVINTGIAHKQAGVGQIGAGITT
                     APMACFVAAVRALAEIVAKENHHG"
     gene            12242..13198
                     /gene="arcC"
                     /locus_tag="LSX49_002504"
     CDS             12242..13198
                     /gene="arcC"
                     /locus_tag="LSX49_002504"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL7168903.1"
                     /translation="MVKPLAVVAVGGNALIQDEQRNSIPDQYVAVMESVQHIVDMVEA
                     GWDLVLTHGNGPQVGFILRRSELASNEVSPVPLDYAVGDTQGAIGYMFQKALHNELAR
                     RGINKPVIALVTQTRVSPHDDAFASPSKPIGAFLDEATAQQRQQQLGWTLMEDAGRGW
                     RRTVPSPAPLEIIEHDTIAHLVRQGYLVIACGGGGIPVVRDGQQLKGVEAVIDKDLAS
                     ALLASQLGADLLVIPTGVEKVAINFGTPQQQWLDAISVAEAQTLLREGQFGVGSMQPK
                     VEAIVDFINASQQQGKQASGLITSPQTIKAALAHQSGTWITL"
     gene            13215..13604
                     /locus_tag="LSX49_002505"
     CDS             13215..13604
                     /locus_tag="LSX49_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA amidotransferase"
                     /protein_id="HBL7168904.1"
                     /translation="MTTTLLAVNGTLMRGLELNPNMQKAGGIFVREDRTDAHYRLWSI
                     NDRHPGMIRVNEGGTHVDVEIWQLPLASFAALLMSEPAGLAIGKIKLADGSEVLGVLA
                     ENWLTEGQREITELGSWRKYTGHFHTV"
     gene            13630..14853
                     /locus_tag="LSX49_002506"
     CDS             13630..14853
                     /locus_tag="LSX49_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBL7168905.1"
                     /translation="MRKKEENLNTASGLRIAMILLGIAVTPVLLSSSSLGNQLSSGSL
                     ISVVLLGGVILTLLSAITISVGEKARLPTYGIVKYSFGEKGAIAINILMAISLFGWIA
                     VTANMFGHSVHDLLAQHGLEVPLALLVAAGCVIFVASTAFGFAVLGKIAQVAVPVIAL
                     VLCYILYVATHTEVAVPAAIVEMNTGVAVSTVVGTIIVLVATLPDFGSFVHNRKHALI
                     AAGVTFLVAYPLLYWAGATPSAISGQGSLLGAMAVFGAVLPAALLLIFACVTGNAGNM
                     FQGTLVVSTLLTRFPKWQITVALGILSAIVGSMDIMAWFIPFLLFLGIATPPVAGIYI
                     ADFFLYRRNGYQESVLAQESQIKVLTFAAWIIGAAVGFMTVKGLFTLTTIPSVDSILV
                     ACIAYAILSRASQHR"
     gene            14931..15836
                     /locus_tag="LSX49_002507"
     CDS             14931..15836
                     /locus_tag="LSX49_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7168906.1"
                     /translation="MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEES
                     LGVELFIRKGRYIELSPAGSYFIEHSKTILGDLEALKRNTVLIHDGIERELTIAVNNI
                     IPGDLLVAFIRDFERQFTSTTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGII
                     SEPVGQMEWDFVVSPLHPLAAKRHPLENSELRHYPAVCIRDTSVNFPPMQAWLLEGQK
                     PIFVPDFATAIALIEQNVGIGYIPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSD
                     GMGKACQWCIEYLRNQQLMTRFVFN"
     gene            16036..16881
                     /locus_tag="LSX49_002508"
     CDS             16036..16881
                     /locus_tag="LSX49_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL7168907.1"
                     /translation="MNNITVKSLIQSNYPTLHQAEKKVADYILSHAHEVVNYSVTELS
                     EKSHASEATIVRTCKKLGYQGYYHLKIALAKEVINPDNSYPENTDFSDITSLATFLLK
                     KQAEDLIQSTQFFNADVLESILKLLANCDTIFFFAAGNSNPLAVYSAYKFSQLGLKTV
                     VHVSPEMQINAAYSMGKRDLAIGISNSGSTNLMVDIFKVVKERGAKSVCITNYIKSPL
                     SKLSTHQLNTAVSDKIFFEAFDSTRVPAMGVIDMLVLLFMYKNKAHYEKYRTREEFLG
                     SRFKG"
     gene            complement(16911..18908)
                     /gene="tkt"
                     /locus_tag="LSX49_002509"
     CDS             complement(16911..18908)
                     /gene="tkt"
                     /locus_tag="LSX49_002509"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL7168908.1"
                     /translation="MNSQLLANAIRMLSVDAIQKANSGHPGAPMGMADIAEVVWRRHL
                     RHNPKNPQWFNRDRYVQSNGHGSMLIYALLHLTGYDLSMDDIRDFRQLHSRTPGHPEY
                     GYTPGVETTTGPLGQGVANAVGMAIAEKALAAEFNKPGFNIVDHHTWLFLGDGCLMEG
                     ISHEACGLAGTLKLGNLIAIWDDNGISIDGHVEGWFAEDTAARFRAYGWHVIEGVDGH
                     DPEAVDAAVREAKSVTDKPSLLCCKTIIGFGSPNKANSHDCHGSALGADEVALVRERL
                     QWPYAPFEIPGEIYAEWDATEKGAQVQQEWDALFADYAKQWPELAAEFTRRMKGDLPA
                     GWVENMQKYVHDLQSHPAALATRQVSQKCLNHFADMLPELMGGSADLSPSNLTRHQKS
                     VDFTGENPAGNYISYGVREFGMSAIMNGLALHGGFIPYGGTFLMFMEYARNALRMAAL
                     MKIRSVFVYTHDTIGLGEDGPTHQPVEQLASLRLTPNMETWRGCDQVEVAVAWQQAIE
                     RKDGPTSLVLTRQPLAQQPRTAAQLAEIARGGYVLSDCDGQPEMILISAGSEIELVVS
                     AAKALTEEGRKVRVVSMPCTERFDNQDAAYKESVLPKAVRKRLAVEASIAGFWERYVG
                     LDGKVIGMTSFGESAPANVLFKHFGFTPENVLAQARELLNS"
     gene            complement(18959..20467)
                     /locus_tag="LSX49_002510"
     CDS             complement(18959..20467)
                     /locus_tag="LSX49_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL7168909.1"
                     /translation="MSKKITSLFNFKKLQKFSSALMLPIAILPAAGLILAIGISFNIE
                     LLANCGGLIFANLPLLFCVGIVIGLTGDGSSSLSAIISYMIMNATMGTQLGITAESVA
                     ASNGDYAMILGVPTLQTGVFGGLIVAIFVYLLYTRFHNIELPQFLGFFGGKRFVPIIT
                     AVAAIIVGYLLPWLWIPVQKGLASLSTLVTSGHNANFAAFIYAVGERSLIPFGLHHIW
                     NVPFYYNFGDYMTKSGQLVTGDIPVFFAQLRDGAPLTAGLFMTGRFPIMMFALPAAAL
                     AMYQEAKPERKALIKGLLLSGALTTFVTGITEPLEYAFLFAAPVLYIIHIFLYATSFV
                     LMNILNVHIGHPFAGGLIDFVLNGVMPNRTPWYLVFLAGAGYAAIYYTVFRVLIRKLN
                     LKTPGREDEEIAVATTLTREERPYQIIEAVGGFDNIEDVDACATRLRLALVDDKKVNE
                     KRLKELGAAGLVKLGDGGVQVIFGGKSQILRDEIKTVMSRPRPTEMTVACAN"
     gene            complement(20509..21066)
                     /locus_tag="LSX49_002511"
     CDS             complement(20509..21066)
                     /locus_tag="LSX49_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL7168910.1"
                     /translation="MDAKLYITEIINELTFVKDSIREDDCTKLIDTIQQSQRVFCYGL
                     GRAGFSMKAFTMRLMHMGKEVYFLTETITPNFGPGDLFIVSSASGETAQLVALAKKAR
                     QLGGAVAVLTTNRHATITEFVDVIVQINAPSKNQKDSVFRSAQPMASLYEQALLVIAD
                     ALVMKMAAESGAPESELFKRHANLE"
     gene            complement(21405..23666)
                     /gene="metE"
                     /locus_tag="LSX49_002512"
     CDS             complement(21405..23666)
                     /gene="metE"
                     /locus_tag="LSX49_002512"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBL7168911.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPQRHQNNDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHKVKPV
                     LLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAV
                     EKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NIDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRRG"
     gene            23784..24737
                     /gene="metR"
                     /locus_tag="LSX49_002513"
     CDS             23784..24737
                     /gene="metR"
                     /locus_tag="LSX49_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HBL7168912.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     ITEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            complement(24625..25524)
                     /gene="bioP"
                     /locus_tag="LSX49_002514"
     CDS             complement(24625..25524)
                     /gene="bioP"
                     /locus_tag="LSX49_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HBL7168913.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALNE"
     gene            complement(25600..26400)
                     /gene="yigL"
                     /locus_tag="LSX49_002515"
     CDS             complement(25600..26400)
                     /gene="yigL"
                     /locus_tag="LSX49_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HBL7168914.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFNYALYEPGLLEPEGVSKVFFTCDSHEKLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLQDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNAEDAVPHYLRKLYLS"
     gene            complement(26408..27430)
                     /gene="pldB"
                     /locus_tag="LSX49_002516"
     CDS             complement(26408..27430)
                     /gene="pldB"
                     /locus_tag="LSX49_002516"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HBL7168915.1"
                     /translation="MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHSGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            27541..28161
                     /gene="rhtB"
                     /locus_tag="LSX49_002517"
     CDS             27541..28161
                     /gene="rhtB"
                     /locus_tag="LSX49_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HBL7168916.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            28320..29180
                     /locus_tag="LSX49_002518"
     CDS             28320..29180
                     /locus_tag="LSX49_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBL7168917.1"
                     /translation="MTEATTPHDAIFKAFLSRPETARDFIEIHLPPSLVKLCNLDTLH
                     LESSSFVEENLRQYYNDVLYSVETTKGCGYIYVLIEHQSSPDENMAFRMLRYAIATMQ
                     RHLEAGHDYLPLVIPILFYQGKRSPYPWSTNWLDGFPDPDIARDLYFHAFPLVDITLI
                     PDDEIMQHRSMAAFTLVQKHIRQRDMTTLLDKLSRLMILGQMSGQQIRMLINYMALVG
                     EAQDVRTLVHGLAQRVPQQGEELMTLAEELRRDALLNVAKAMLQRGFDLQLIMEMTGL
                     SQEDLYQLQS"
     gene            complement(29218..29838)
                     /gene="rhtC"
                     /locus_tag="LSX49_002519"
     CDS             complement(29218..29838)
                     /gene="rhtC"
                     /locus_tag="LSX49_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709629.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HBL7168918.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEVVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVET
                     LAWFTVVASLFALPQMRCGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(29903..31732)
                     /gene="recQ"
                     /locus_tag="LSX49_002520"
     CDS             complement(29903..31732)
                     /gene="recQ"
                     /locus_tag="LSX49_002520"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBL7168919.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLEVMTGCRTGQISLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            complement(31857..32726)
                     /gene="pldA"
                     /locus_tag="LSX49_002521"
     CDS             complement(31857..32726)
                     /gene="pldA"
                     /locus_tag="LSX49_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HBL7168920.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYIIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSDESSPFRETNYEPQLFLGFATDYNFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            32891..33358
                     /locus_tag="LSX49_002522"
     CDS             32891..33358
                     /locus_tag="LSX49_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HBL7168921.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            33410..>34269
                     /gene="rarD"
                     /locus_tag="LSX49_002523"
     CDS             33410..>34269
                     /gene="rarD"
                     /locus_tag="LSX49_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HBL7168922.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFAFI
                     WVALAIFVMDA"
BASE COUNT         8435 a         8990 c         8599 g         8245 t
ORIGIN      
        1 atattgtggg atatatcacc ttttccccac gtcattatgt ggaacacttc agcaatatca
       61 tcaggagaaa cgtatggcag aaacctcttc aaccaccgca ggcgcacaaa cgttattacg
      121 tggactggcg gttcttaatg ctgtttataa cggctgccat gacctaaaaa gtatcggcga
      181 gttcaccggc acgacccgga gcacaaccca tcgtttagtc accgttctgg tggaacaacg
      241 ctacctgcgc catgtcccaa cgcagggcta ccaactgggt gccaaactga tcgaattcgg
      301 tgccagagca ctggaaagca cctcgctgta cgaaattgcc cagcccgttt tgcaacgcct
      361 tgcccgttac accctggaca ccgtgcatct ggggatcgtt gaaggcgacg aagtgctgta
      421 tctggagaag atcaacagtc agcgcgggct ggaaatgcgc tcacgcccag gccatcgcat
      481 gccactggca atcaccggca tcggcaaggc attgatcctc aaccgaacag aagaagagtg
      541 gcgcacgctg tttaagacct gtggtgatga aacaaaactg ggcgcattta ttcagaacat
      601 gcgtcgttat gccgccagtg gttttgcttt tgatctggaa gagaacgagc cgactatccg
      661 ttgcgttgca gcgccggttt acaacgcccg ggatgaaatt gtggcggcta tttctgtcgc
      721 cagtaccacc acgtatatgt cgctggcgcg tctggaagaa ctggcacctt acgtcaaatc
      781 ctgtgcagaa gagatatccg ctgaactggg ctggggtaag cacgtccgca aagataaata
      841 aaccatgatt aaaggaaacg actaatgccg ggagcaccct catttattgc cctggactgg
      901 ggaacgtcat cgcttcgggc atggcgtttt ggcgaatcac caaatccaca agaaaaacgt
      961 gaattcccct gggggatcat gaaattaccc tcccaggcag caacacgtga ggacgctttc
     1021 cacgatacgt ttttacgtgt ctgcggcgac tggctggcac aaaccccatg cccggtactg
     1081 gcttgcggca tgctcggcag tgcgcaaggg tggcaaccag cagcttattt accttgcccg
     1141 gtcactctcg agggtctggc gaagcagttg acgcctgtta tccaccagca gcagacaatg
     1201 ctgcacatca ttcctggcgt gattaaagaa ggtgaaatgc ccgaagtgat gcgtggcgaa
     1261 gagacacaaa tcttcggtgc tatctcgatg gaaccgtccc tgcaaaatgc gatccatcag
     1321 ggtatgccag tgctgatagg cttacccggc acacatgcga aatgggcagt agttgaaaac
     1381 aacaccatta ccgatttccg aacctttatg acgggcgagt tatttgatgt tttatcccgc
     1441 cattcgattc tcggtgccac catgcatcct ggagatgaac tgcactggga tgccttcacc
     1501 cacgggctga cagcagcaca agagcatcat cagaccggat tattatcgac gctgttttcg
     1561 acccgttcgc gcctgctgac cagtaatctt acgtcgtcct cgcaggggga ttacctttcc
     1621 ggattactga taggccatga attatgtggt ctggcatcca gtttgctacg tgatttaccc
     1681 gccacaacac cgatcgcctt aatcggtagc gcaaatctga acagccgcta ttcacaagca
     1741 ttcagccacg tttttcccga cagacagata cacgccattc ctaatgccac tgaacaggga
     1801 ttatggcgaa tcgcccacgc tgccgggtta ctgtccacca acgccaggga atgtacccat
     1861 gccatttaat acgcttttgc aaaaaaccgg gttagtcgcc attttacgcg gcgtgaaacc
     1921 ggatgagatt gtcgccatcg gtgaaaaact gtacgccgcc ggattccgcc tgattgagat
     1981 tcctatgaac tcgccggagg cgttgcaaag tatcagttta ctgcgcgacg ccctgcctaa
     2041 ggactgcctg gtcggagccg gaactgtgct ttcggtagag caggtggttg cggttaaaga
     2101 ggctgggggc cagattatcg tgatgccgca ttgcgatact gcggtgatcc gtcgcgcccg
     2161 tgcgctgggt atgtattgtg cgcctggcgt cgccacgccc accgaagcct ttactgccat
     2221 tgaacatggt gctaatgcca tcaagctgtt cccggctgaa caaattacgc cagaagttac
     2281 caaagcctgg cgtgcggtta ttccacaatc cgttccgatg ttaccggttg gcggtatcac
     2341 accggaaacc atggcgcgtt atctgagcca cggcgcaaac ggctttggcc tcggttctgc
     2401 gctatatcac cccggcatga cgccagagca agtctatgaa aatgcagtac tgtttatgaa
     2461 cgcatggaac aatttaaata gcaactaact gataaataag gatataaaag caatgataaa
     2521 acatcttacc ttaccgaaaa aaatggctgc aatggtactt cttgcaggcg ctgccctcag
     2581 cattgcgcct gtacaggctg cctcctggcc aaccaaacag atcgagttag tcgttcccta
     2641 cgctgccgga ggcggtacgg atctggttgc ccgtgccttt gctgatgccg ccaaaaacca
     2701 tttacccgtc agcatcgggg ttatcaataa acctggcgga ggcggtgcta tcggcctgag
     2761 tgaaatcgcc gctgcccgcc ctggcggtta caaaattggt ttaggcacgg ttgaactgac
     2821 cacccttccc agcctcggaa tggtgcgttt taaaaccagc gactttaaac ccattgcccg
     2881 tctgaatgcg gatccggctg ctatcacagt ccgtgccgat gcgccgtgga atagctatga
     2941 agaatttatg acttacgcca aagcgaatcc cggaaaagta cgcattggta actcaggcac
     3001 cggagctatc tggcatctgg cggcagctgc actggaagac aaaacgggcg caaagttttc
     3061 tcatgtcccg tatgacggcg cagcccctgc cattacaggc ctgttaggcg ggcacattga
     3121 agcggtttcc gtaagcccag gagaagttat caaccatgtg aaaggcggca agctgaagac
     3181 actggtagtg atggcggatg agcgaatgaa aaccatgcct gacgtcccga cgttaaaaga
     3241 gaaaggcgtt gatctctcca tcggcacctg gcgcggcctg attgtgtcgc aaaaaacgcc
     3301 gcaggatgtg gtggatgttc tggcaaaggc agcaaaagag acggctgaag agcctgcatt
     3361 ccaggatgca ctacaaaagt tgaatctcaa ctatgcatgg cttgacgctg ccagcttcca
     3421 gacccaaatc agcgaacagg aaaagtactt tgacgagttg ctgactcgcc tgggcctgaa
     3481 aaaataaacc tgaggtacgg ttgatgaaca caaaacagtc tgttgctcaa ctcgccgtac
     3541 cgcaccgcaa gcgcctttca tcaacgatgg tggtggcgct gttactttgt gtggttgctg
     3601 gcgcggtgat gattaatgcc gctgattttc cagcaactgc cattgaaacg gatcccggtg
     3661 caagtgcctt ccctaccttc tatgcctgtg ccctgattgt gctcgctgtc ttgctggtga
     3721 tacgcgatct tttgcaggca aaaccagcct cttgcgccaa cgcacaggaa aaaccggcat
     3781 tcaggaaaac ggcaacagga attgcggcaa ccgcgtttta tattgtggcg atgagctact
     3841 gcggttatct cattactact cctgttttcc tcatcgtcat tatgacgttg atgggctaca
     3901 ggcgatgggt actcacaccg ggtattgcgc tgctgttaac ggcaatcctc tggttgctgt
     3961 ttgtcgaagc gttacaggtg ccattgcctg tcggcacatt tttcgaataa caggggccag
     4021 caatgtttga aagtgaactt ttaactcagg gtttttcgac attactcaat aatcctcagg
     4081 cgctgctgtt tgccactttt ggggtgatgc tgggtattgt gattggcgct ctgcctggtc
     4141 tgacagcgac catgggtgtg gcgattttgc tgcctttcac ctacggcatg gagcctgttt
     4201 ctggcttgtt gatgatttgc ggcgtctttt ttggcggcgt ctatggcggt tctatcaccg
     4261 caattttgct caaaattccc ggtacgcctg ccgccgcagc caccgccatt gacggatatg
     4321 agctgacgaa gcagggaaaa gcagggctgg cattgagtgc cgccacgttc tcttccttta
     4381 gtggcggaac gctcagcatt atcgtgctga tgtttctctc tccggtactt gccagttggg
     4441 cgctgaaatt tagtgcctcg gagtccttcg ccctggcaac cttcggactg agcattattg
     4501 ccagtatttc cggtgagtcg ctgattaagg ggctgattgc cggggttggc ggattgctga
     4561 tcgcaacgat aggccttgat ccaatgggcg gttttccacg gtttacaggt ggatttgtgg
     4621 agctgatgaa tgtgccattt atcccggtga tgattggttt atttgctgct tcagaagcat
     4681 tccgctctat ggagcaaaac cagcaaattc gtcagggggc gaaggtggct atcggcagtc
     4741 tgttactgcc ctggcaaaca ctacgccgca tcgcattaac cattttgcgc tcatcaggat
     4801 taggggtttt tatcggcatg atccccggtg cgggggcgga tattgcagct tttgttgcct
     4861 ataacgaaac tcgtcgtttc agtaagacac cagaaaactt tggtaagggt gaaattaaag
     4921 ctgtggcctc ctgtgaggca ggcgcgaatg gctgcaccgg tggcgcattg ttacctatgc
     4981 tgacgctggg gatccctggc gatgcggtaa ccgccatcat gctgggcgcg ttaacgttac
     5041 agggaatgca accaggcccg ctgatgttta ccgaccacgg cgatatggtt tatacactgt
     5101 ttgtcggcat gatcttctgt tacttcatgc tactagttct tggactgctc tctttgaaag
     5161 tcatcggtaa tgtggtgaaa attcccggca atattctcac accgatgatc ctcgcacttt
     5221 gtgtggtcgg gacttatgcg ttgaacaata gcctttttga tgttggcatt atgctgattg
     5281 caggcgtggt gggctatttc atgcagaaag gaggatatcc ggcatcaccc gtagtgctgg
     5341 cattgattat ggggccaatg gcggaaagta attttcgccg tgcgctgtcg ctttctggtg
     5401 ggtcactcga ctttctgtat acccgaccga tcactctggc attgctgact ctggcagcct
     5461 ttacgctact gacgccaata atccgcaaaa taatgcgttt acggcgtcaa taactgatat
     5521 cgctccccga agttggggag cgttttttta tttcagcaga cgacgcgccg cttccaccac
     5581 gattttcacc gcatggcttt cggtttgttt catcgtctca gcattcggga tctcttgctg
     5641 ggtgcggtta acgataaccc ccgctaccat accggcacgc aggccctgac ttgcacacat
     5701 ggtcagcagg gttgcagatt ccatttcata gttcattacg cccatcgcct gccactcttc
     5761 catagaacct ttaaagtgac gaactacgcg accagagtaa gtatcgtaac gttcctgacc
     5821 tgggtagaag gtatcagaag aagctgtcac gccaacgtga gtcgtcgcgc caatggattt
     5881 cgcagcttca accagcgcag tcgtacattc gaaatcagcg acagccggga attccagcgg
     5941 tgcgaagtgc aggctcgcgc catccagacg aacagacgcc gtggtaacca ggacatcacc
     6001 cacattaata tgcggctgaa tagcgcccgt tgtaccgata cgcaggaagg tgcgaatgcc
     6061 cagctgtgcc agctcttcaa cagcaataga ggtagacggg ccgccgatac cggtagagca
     6121 gacgataaca ggtttaccat ccagctctgc acgccaggtg gtgaattcgc ggtgagatgc
     6181 cagcttaacc ggcttatcca tcagcgcggc gatcttttcc acacgatccg ggtcgccagg
     6241 gacgatggca agcgtagccc cttgtaaatc gtttttagtg aggccgagat gaaaaacatc
     6301 agacttggac atatacaact cctctgtgaa tcggtttagt cagaagaagc aaaaagacac
     6361 tttaccgaag ggtttaacat tttttcgtga tactcatcac catgacgaaa atgtgttgca
     6421 taaatttacc catcaaaagt gatgcaaatc acataaatca ctcttcattc tgcaggactg
     6481 cataaaagat gagccgattc aggcaatgtg atttgttgca tgctgactat agttaacatt
     6541 gcgcaacatt tttataaggg tacggagaat accatggcaa caacacaaca atctggattt
     6601 gcacctgctg catcgcctct cgcttcgacc atcgttcaga ctccggacga cgcgattgtg
     6661 gcgggcttca cctctatccc ttcacaaggg gataacatgc ctgcttacca tgccagacca
     6721 aagcaaagcg atggcccact gccagtggtc attgtagtgc aggaaatttt tggcgtgcat
     6781 gaacatatcc gcgacatttg tcgccgtctg gcgctggagg ggtatctggc tatcgcacct
     6841 gaactttact tccgcgaagg cgatccgaat gattttgccg atatccccac gttgcttggc
     6901 ggtctggtag caaaagtgcc tgactcgcag gtgctggccg atctcgatca tgtcgccagt
     6961 tgggcttccc gcaacggcgg cgatgttcat cgtttaatga tcaccggatt ctgctggggt
     7021 ggacgtatca cctggctgta tgccgcgcat aatccacagc taaaagccgc agtggcgtgg
     7081 tacggcaaac tgacgggcga taagtcgctg aattcaccga aacaacctgt tgatatcgca
     7141 accgatctta acgcgccggt tctcggctta tatggcggcc aggataacag cattccgcaa
     7201 gagagtgtgg aaacgatgcg ccaggcgctg cgggcagcaa acgcgaaagc agagattatc
     7261 gtgtacccgg atgcagagca tgcgttcaac gccgattatc gtccgagcta tcatgccgag
     7321 tctgcgaaag acggctggca gcgaatgttg gaatggttta cacagtatgg tgttaaaaag
     7381 taacgccata gtcgctaaat ctgatgatta agctcacaca atttcaacga tttttttaat
     7441 ctcaaaacca tacagcatca aaaaatttgt tgctgtatgc cactctttga ctcccttcac
     7501 attcgtcatc acaccacctg ctgaatgcaa aaatttcgtt gctgtgcggc aaactttttt
     7561 cctgttttgt gccgcttttc tcctgaatac tcgttctcag aacaactgga tcgtttaaac
     7621 atcagacagg agatttacca tgacgcaatc catttttcag gctcaaccct ttgaattacc
     7681 ttttgatccg cgcacaactg cactggtcat gatcgacatg cagcgtgact ttgtcgaagc
     7741 cgggggcttc ggtgaggcac tgggcaatga tgtttcacgg gtacgcacgg ctatcgcacc
     7801 atgtacagag gtgctggcag ccgcacgtca aaaaggaatt atggttattc atactcgtga
     7861 aggccatcgt gcagacttaa gcgactgccc gccagccaaa ctgacgcgcg gcggaaaaac
     7921 ctttattggt gaaccaggac cgatgggacg cattctggtc agaggtgaag caggtcatga
     7981 catcattcct gaactgtacc cggtggcagg cgaaccggtg attgataagc ctggcaaagg
     8041 cgcgttttat caaaccgact tacatctgat tttgcaaaac cacggtatca agacgctgat
     8101 agtttgtggt gtaacaaccg aagtttgcgt aaccaccacc gtgcgcgaag caaatgatcg
     8161 tggctatgaa tgcattatcc cggaagattg tgtcggctcc tatttcccgg aattccagaa
     8221 atacgccctc gagatgatca aagcacaagg tgccattttc ggttgggtta ctgattccaa
     8281 agccattatt gcaggtctgg aaggctaacg ccgatggtac aggttacgct ttgcgcatcg
     8341 tcgttgggat atcttttccc gcaggatgaa acgcaagatt tacgtctaca tagcgctttt
     8401 aaacatgcgg taaatctgta ttcagacgcg ggaacattca tcactctgtt gtgtgcgcaa
     8461 acgtatctga atctccctga tgctgccaga gtctggctac ctgaatgttg ggactggcga
     8521 agagagattg cccattcaga tcccattcag ttaaccccag gcttgctgcg gacacctcga
     8581 ttttgtgtgg cgctcgataa cgcaacgctc tggcagtcgc catttgtggg gggaatgctg
     8641 acacttgagg cattcccttt ggttttccag cactacccaa cgatggcatc gcaacggctt
     8701 ttattttgtc tggagcataa cgttcaaagc acattgcacc tgccggatag tctcacgcac
     8761 cagggattag cgattatgga gcatccagat gcgctggaac gccaggtgcc acaactgatc
     8821 ggctttggta aaggcttaac gcccgatgga gatgactatt tgttgggcta tctggcagcg
     8881 ctctggttat ggcaactccc tgcaccactt gccgatcatc aataccggtt gcagcaggca
     8941 attgatcaac atgcgcacaa caccacggat atcagtcgtc attatctgga gcgtgcgctt
     9001 cagggacatt tttcagaacc gatttgccag ttactcgcac aactggttgg gagcgcatcg
     9061 gcaatgacaa tcgcatcctg tgcagaacag gtcatgcaat ttggcgcaac gtcaggagta
     9121 gattgccttg caggaatgct gcatggcttt cgaaccctga acaccatgaa ttgatttcaa
     9181 ccttttctcc cgtagcccgt ttatggggct acacggggat gctttgcccg aattttgcta
     9241 tcgggcggaa tgaaacaggc gtaacagcat gaaagttaaa tataaagttt tcagtaatct
     9301 ttatcaggac tcagtttctc tgatgcagat ttccgcgcaa atcagcaagt tgcccggtat
     9361 tcaacaggcc tcggtcgtca tgggaacgcc caataatctc gaacaattgc gcgatgcggg
     9421 tctgggtaac gaaatcaacg ccagtcccaa tgatttagtg attgcagtca tgggtgaaga
     9481 agatatttgc aatgaagcac tgatactggc ccagcaacgt ctgaccagca aacccgatga
     9541 tgaaacggat agtggcatta aaacaccgga aaaggtcagc ctggaaatgg cactggaagc
     9601 cgaacccgaa gccaacctgg cactcatttc tgtaccggga gactacgccg ccgccgaagc
     9661 aattaaagcg ttaaacctcg gaatgaacgt gatgatgttc agcgataacg tcagtatcgt
     9721 gcaggaaaaa tccatcaaaa cgcttgcccg agaacgtcag cgcatcgtaa tgggacctga
     9781 ctgtggaacc gccattgtta acggcattcc gttaggcttc gctaatgtgg tgaaacgcgg
     9841 agcaattggt gttattggcg cgtcaggcac cgggctacag gaagtgactt gccgaatcga
     9901 ccagctcgga gcgggtattt ctcaggcgtt gggaacaggc ggacatgatc tcagtaaaga
     9961 gattggtgga atatcgatgc tcttcgcttt agatgcgctg gcgcaagacg atgaaactcg
    10021 cgtaattgtg ctgatttcaa aaccgccttc accgatcgtt gcccggacta ttctggagcg
    10081 cgccgaggct tgtggaaaac ccgtggtggt gaatttcctc ggggcgaatc cgcatgatct
    10141 ggcacgtccc aatatcactg ccgccaccac acttgccagc gccgccgaca tcgctgtggc
    10201 gttactgaat gctcagccac ttccggctgt cgaaaccgat gtaccctgcg acgatctcac
    10261 aatgttacaa aacgcctgcc agcgcctgcc agcccatcgc caggcgatac gcggtgtttt
    10321 cgccggagga accttctgct acgaagcgca acttatctgc caacaaaagg gattcagcgc
    10381 agcttccaat acgccagttg cgggtaatcg tgctctggca aatatctggc aaagcgaaga
    10441 tcacacgttg atcgatatgg gcgacgatga tttcacccgt ggcaaaccgc atccaatgat
    10501 cgacccgact ctgcgcaatc aacgtctgct caacgaactc aacgactcac acactgccgt
    10561 cgtgttattc gacctggtac ttggttatgg cgcttccacg acgcctgcca gcgaattact
    10621 ggaccaactt tcacacatcg acatgaataa cgctccgttg ctgattgcgc acgtttgcgg
    10681 aacggaagct gatccgcaaa tacgcagtca gcagataagc gcactacaaa atgcaggggt
    10741 catcatcgcc agcagcaatg cacaggcggc gctatgggcc agcaccgttg cacagactca
    10801 gttgcagaaa aaggggctaa acgcatgaat accttattta atcagccttt gaaggttgtg
    10861 aacgcgggac tacacagttt tgctgacaat attcaacatg ccgggggaag cgcaattgca
    10921 ctcaactggc agccaccagc acaaggcgat attgacgctg gattggatct ggcatcgttg
    10981 ctacgtcatc ccctggtaga aaatgccaac caaatcgcca tggcacgtta tctcgaagca
    11041 cagcccgtgc tggtggatgt catgcttgct aaagaggcca ttccagcaat ggctgaacaa
    11101 aaacgtattt tgcactctgg cccgccgatt gcctgggaag agatgtgtgg tccggtaaaa
    11161 ggggcgatta ttggtgccat gctgtacgaa ggttgggcca ccagccagca agacgctgaa
    11221 aaccagataa acgcaggcga aatcgacctt gccccttgtc atcattatca cgcggttggc
    11281 ccaatggcag gcatcatcag cccgtcgatg ccgttatggg tggtagaaaa caaaaccaac
    11341 ggccaccgta cttttagcaa tttcaatgaa ggtctgggta aggttctccg ttttggcgcc
    11401 aataacgatg aagttctcaa tcgtctggcc tggatgcgcg atgaactgac gccggcaatg
    11461 aaagcagcaa tcgcacaaca cggcgagctg gaactcaagc cattaatggc gcaggcgctg
    11521 catatggggg atgaagttca taaccgcaat gctgccgcta ccggtttgct gattaagcgc
    11581 ctgctcccgg cattgctggc ctgctctctt ccacaggaac atatccagcg cgtcgtggca
    11641 tttatcaccg gtaacgatca cttcttcctc aatctgtcga tggccgcctg taaagcaatg
    11701 atggatgccg ccgccaatgt accgttcagt tcaatggtta cggtgatggc gcgtaacggg
    11761 gtgaattttg gtattcggat ttccggtact ggcgatcgct ggttccaggc tcctgccaat
    11821 gccgttgaag gtctgttctt ccccggattt ggcgttgacg acgctgctgc tgacctgggt
    11881 gatagcgcaa ttactgaaac cgcaggtgtg ggtggcttcg cgatggcgtc gtctccggcg
    11941 atcgtcaaat ttgtgggagg cacccctgcc gatgccacca ataacagccg tcggatgcaa
    12001 gccatcaccc tcggcggtaa ccccgcattt acacttccag ccctcaattt tgcccccacc
    12061 gcagcaggga ttgatgcgcg taaagtgacc gatcgcggca ttttaccggt catcaatacg
    12121 ggtatcgccc acaaacaagc gggggtcggg caaattggtg ccgggatcac cactgcgccg
    12181 atggcctgtt ttgtcgccgc tgtacgtgca ctggcggaga tcgtcgcaaa ggagaaccat
    12241 catggttaag ccactggctg tcgtcgcggt tggcggcaat gcgctcattc aggacgagca
    12301 acgcaatagt attcccgatc aatatgttgc agtgatggaa agcgtgcagc atatcgttga
    12361 tatggttgaa gccggatggg acctggtgct aacccacggt aatggcccgc aggtgggctt
    12421 tattctgcgc cgctctgaac tcgccagtaa cgaagtttct ccggttccac ttgattacgc
    12481 cgtgggtgat acacaaggtg caattggcta catgttccag aaagcgctgc ataacgaact
    12541 cgctcgccgt ggcataaaca aaccggtaat tgccctggtg acacaaacgc gagtcagccc
    12601 acatgacgat gctttcgcca gccccagtaa accgattggc gcgtttctcg atgaagcaac
    12661 ggcccaacaa cgccaacaac aactcggctg gacgctgatg gaggacgccg ggcgtggttg
    12721 gcggcgtaca gttccctctc ctgcaccact ggaaattatt gagcacgaca ccatcgctca
    12781 cctggtgcgc cagggatatc tggttattgc ctgcggcggc ggcggtattc cggtggtgcg
    12841 agacgggcaa caactgaaag gtgtagaagc cgtgatcgat aaagatctgg cctccgcgct
    12901 gctcgccagt cagttaggcg cagatctgct ggtgatcccc accggtgtag aaaaagtggc
    12961 gattaacttt ggtacaccac aacaacagtg gctcgacgct atcagcgttg ccgaagcgca
    13021 aacgctgttg cgggaaggtc agtttggtgt cggcagtatg caacccaaag tggaagccat
    13081 tgttgatttc atcaatgcca gccagcaaca aggcaaacag gccagcggcc tgattacttc
    13141 accgcaaacc ataaaagcag ccctggcgca tcagagcggt acatggataa ccctttaatt
    13201 ctctggagaa cacaatgact acaacgcttt tagccgttaa cggaacgctg atgcgcggcc
    13261 tggaactcaa cccaaatatg caaaaagcgg gcggtatttt tgtccgtgaa gaccgaactg
    13321 acgcccatta ccggttgtgg agtattaatg atcgccatcc gggaatgatt cgcgtgaatg
    13381 aaggaggaac acacgtcgac gtagaaattt ggcaattacc gctggccagt tttgccgctc
    13441 tgttaatgag cgaacccgct gggctggcaa ttggcaaaat caaacttgcc gatggtagcg
    13501 aagtgctggg cgtactggca gaaaactggc tgaccgaagg ccaacgggaa attacagaac
    13561 tgggtagctg gcgtaaatac accgggcatt ttcatactgt gtaacgcgca tttataaagg
    13621 gaacatacta tgcgtaaaaa agaagagaat ctgaatacgg catcaggatt gcgtattgcc
    13681 atgattttgc tgggtattgc cgtcacacct gtgctgttgt catcctcaag cctcggcaat
    13741 caactttcca gcggcagttt aattagcgtc gtattgttag gcggcgtcat tctgacctta
    13801 ctttcagcca tcaccattag cgtgggagaa aaagcccgcc tgccaacgta tggcattgtg
    13861 aaatattcgt ttggcgaaaa aggggccatc gccattaaca ttttgatggc gataagtctg
    13921 ttcggctgga ttgccgttac cgccaatatg tttggtcatt cggtacatga cttactggct
    13981 caacatggac tggaagttcc actggcactg ttagtggcgg ctggctgtgt catttttgtc
    14041 gcctctacgg catttggctt tgccgttctg ggaaaaattg cccaggttgc cgtgccggtt
    14101 atcgcgctgg tgctgtgtta catcctctat gtggcaaccc ataccgaagt ggcagtacca
    14161 gcggcgattg tggagatgaa tacaggtgtc gccgtttcca ccgttgttgg caccattatt
    14221 gtgctggttg ccacactgcc tgatttcggt agttttgtgc ataaccgcaa acatgcgctg
    14281 attgccgcag gcgtgacgtt tctggttgcc taccctctgc tctactgggc gggtgcaacg
    14341 ccgagcgcca ttagtggtca gggatcttta ctgggtgcga tggcggtatt cggtgcagtt
    14401 ctgcctgcgg cgctgttgtt gattttcgcc tgcgtcaccg gtaacgcggg caatatgttc
    14461 cagggcacgc tggtggtttc cacactgctt acccgctttc ccaaatggca gattaccgtg
    14521 gcgctgggta tcctttccgc catcgtaggc agtatggata ttatggcgtg gtttattccg
    14581 tttctgctgt tcctgggtat cgccacgcca cccgttgccg gaatttatat cgctgacttt
    14641 ttcctttatc gccgtaatgg ctatcaagag tcagtgttag cccaggagtc acagattaaa
    14701 gtgctgacat tcgcagcatg gatcataggc gcagcggttg gctttatgac cgtaaaaggc
    14761 ttattcaccc tgacgacgat cccttcggta gactcgattc tggtggcatg tatcgcgtat
    14821 gcgattctca gtcgggcaag tcaacaccgc taattcctgg gtatactcag gcaatgatta
    14881 cggctgaatc tggagagatt cagccacttt accactgacc agggagcctt atgttcatct
    14941 cagacgaaac gcttcgtgtt attcatctgg tcgccagaca ccagagcatt accaccgcag
    15001 ccgagcagtt aaataaagtc ccttccgcca tcagttacac catcaagaaa gcggaagaga
    15061 gcctgggcgt tgaactgttc attcgtaagg gacgctatat tgaattatcg ccagcgggaa
    15121 gttacttcat cgaacatagc aaaactattc ttggcgacct ggaagcatta aagcgcaaca
    15181 cagtgctgat tcacgatggt attgagcgtg aactgacaat tgcggtaaac aatattattc
    15241 ctggtgattt gctggtggca tttattcgag attttgaacg gcaattcaca tcaacaacac
    15301 tgacggtaga tcttgaggta tacaacggct gctgggatgc gctgtacagt aagcgtgctg
    15361 atctggtcta cggtgctcct catgcagtac caagcagtga aggcatcatt agcgaaccgg
    15421 tcggacaaat ggaatgggat tttgtcgtca gcccactcca cccactggca gcgaagcggc
    15481 atccattaga aaacagtgaa ttgcgtcatt atccagcggt ttgtatccgc gatacctccg
    15541 ttaacttccc cccgatgcaa gcctggttgt tggaaggaca aaaacccatt tttgttcctg
    15601 acttcgctac ggcaatcgcc ttaatagaac aaaacgtcgg tattggttat attccacatc
    15661 atctggcatt accgttattg aacagcggta aattgcttaa aaagccaatg cgcgaacata
    15721 aacacgccac caagttattt cttgccgctc gttccgatgg tatgggcaaa gcctgtcagt
    15781 ggtgcataga atatttaaga aaccagcaat taatgacacg atttgtattt aattgacaat
    15841 acaatgataa aaatataagt cttgctttaa ttagagcgcc cgtttaaatt atttttgtgc
    15901 agttgacgta attcatgaaa attaaccggt ctgttaatca ttacgttcac tgcacacctt
    15961 cattttttca cacctatcca cgcctgaaaa ctatgttata atcagcactt tctgtcagaa
    16021 tgaaatttac taattatgaa taacataacc gtaaaaagtc tgattcaaag caattaccct
    16081 acactgcatc aggcggaaaa aaaggtcgct gactatattc ttagccacgc acatgaagtc
    16141 gtgaactata gtgtcactga actatcagaa aaaagccatg ccagtgaagc gactatcgta
    16201 cgcacctgta agaaattagg ttatcagggt tattaccatt taaaaattgc attagcaaaa
    16261 gaagtcatta atcctgacaa tagctatcct gaaaataccg acttcagcga tataacatct
    16321 ttggcaacct ttttattaaa aaaacaggcc gaagatttaa tacaatcaac gcaatttttt
    16381 aatgccgacg tgcttgagtc cattctcaaa ctacttgcta attgcgatac tattttcttt
    16441 tttgctgccg gaaattcaaa cccactggcc gtttatagtg cttataaatt cagccaactc
    16501 ggattaaaaa ccgttgttca cgtcagcccg gaaatgcaaa ttaatgcggc atattctatg
    16561 gggaaacgcg acctggcgat tggtatttct aactctggca gcaccaactt aatggtcgat
    16621 atctttaaag tggtgaaaga gcgcggtgcc aaatccgttt gtatcactaa ctatattaaa
    16681 tctccgttat caaaactctc cacccatcaa ctcaataccg cggtcagcga taaaatcttc
    16741 tttgaagcct tcgactccac tcgcgttccg gcaatgggcg ttattgatat gctggtgctg
    16801 ttgtttatgt ataaaaacaa ggcgcattac gagaaatacc gcacccgtga agagtttctt
    16861 ggctcccgtt tcaaggggta aaaggtcatc ctttcacccc ttgtgcaggt ttagctgttc
    16921 agtagctcac gcgcctgcgc caggacattt tccggcgtaa aaccaaagtg tttgaacaac
    16981 acattcgccg gagcagactc accaaagctc gtcatgccga tcactttacc gtccaggccc
    17041 acgtagcgtt cccagaatcc ggcgatgctg gcttctaccg ccagacgttt gcgtacagct
    17101 tttggcaata ccgactcttt gtacgccgca tcctgattat cgaaacgctc ggtacacggc
    17161 atggaaacca cgcgaacttt acgcccttct tccgttaacg cttttgcggc gctgaccact
    17221 aactcaatct ctgaacccgc agaaatgagg atcatctcag gctgaccgtc acaatcactc
    17281 agtacataac caccacgcgc aatctctgcc aactgtgcag cggtgcgcgg ctgttgcgcc
    17341 agaggttggc gcgttaatac caacgacgtt gggccatctt tgcgctcaat cgcctgttgc
    17401 caggccaccg ccacttccac ctgatcgcaa ccgcgccagg tttccatatt cggcgtcaga
    17461 cgcagcgacg ccagttgctc aacgggctga tgtgtcgggc cgtcttcgcc caggccgatg
    17521 gtatcgtggg tataaacaaa caccgagcgg atcttcatca gcgccgccat gcgcagtgca
    17581 ttacgcgcat attccataaa catcaggaaa gtaccgccgt aagggataaa cccaccatgc
    17641 agcgcaagac cgttcatgat ggccgacata ccaaattcac gcacgccata ggagatgtaa
    17701 ttccccgccg gattttctcc ggtgaaatca accgatttct gatggcgagt caggttagag
    17761 ggcgacaagt ccgccgagcc gcccatcagt tccggcagca tatctgcgaa gtgattgagg
    17821 catttctggc taacctgacg ggttgccagc gccgccggat gggattgcag atcgtgcaca
    17881 tatttctgca tattctcgac ccagccagca ggcaaatcac ccttcatgcg acgagtaaac
    17941 tccgccgcca gttccggcca ctgcttcgcg tagtcggcaa acagtgcatc ccattcctgt
    18001 tgaacctgcg cgcctttctc ggtcgcatcc cattcggcat aaatttcacc aggaatttcg
    18061 aaaggggcat acggccattg cagacgttca cgcaccagcg ccacttcatc tgcacccagc
    18121 gccgagccgt ggcaatcgtg gctgttggct ttatttggcg aaccaaaacc gataatcgtt
    18181 ttgcagcaca gcagactggg cttatccgtg acgcttttcg cttcacgcac cgcagcatct
    18241 accgcttctg gatcgtgacc atcaacgcct tcaatgacat gccagccgta ggcacgaaaa
    18301 cgggcagccg tatcttcagc gaaccagcct tctacgtgac catcgatcga aataccgtta
    18361 tcgtcccaga tagcaatcag attgccgagc ttcagcgttc ctgcaagacc acaggcctcg
    18421 tgggagatcc cttccatcag acagccatca cccaaaaata accatgtgtg atgatcaaca
    18481 atattaaagc ccggtttgtt aaattctgcc gccagcgcct tctccgcaat cgccatcccc
    18541 accgcattag ctacgccctg ccccaacggg ccggtggtgg tttcaacacc cggcgtataa
    18601 ccatattctg gatgacccgg cgtgcgggag tggagctgac gaaagtcgcg aatatcatcc
    18661 atcgacaggt cgtagcctgt aagatgcagc aaagcgtaaa tcaacatgga gccgtgaccg
    18721 ttcgactgaa catagcggtc gcggttaaac cactgcggat tttttgggtt atgacgcagg
    18781 tgacgacgcc agaccacttc ggcaatatcc gccatcccca tcggcgcgcc cggatgaccg
    18841 gagttcgctt tctggatcgc atcaacactt aacattcgga tggcattagc cagtaattgt
    18901 gaattcatac ttcagctctc tctgtctggc gggctgaaac cagcccgcta atctcgaatt
    18961 agttagcaca ggccactgtc atttctgtcg ggcgcggtct gctcattacg gttttgattt
    19021 cgtcgcgcag gatttgcgat ttgccgccaa atatcacctg tacaccgcca tcacccagtt
    19081 tcactaaacc cgcagccccc aactccttca gccgtttttc attcactttc ttatcgtcta
    19141 ccagcgccag ccttaggcgt gttgcgcagg catccacatc ttcgatattg tcgaaaccac
    19201 ctactgcttc gatgatttgg tatggacgtt cttcgcgcgt taatgtggtt gcaacggcaa
    19261 tctcttcatc ctcacgcccc ggtgttttca gattcaactt gcggatcagt acccgaaata
    19321 cggtgtagta aatcgctgca tagcccgcgc ctgccaggaa caccagatac cacggcgtgc
    19381 ggtttggcat aacgccattc agtacgaaat caataagacc gccagcaaaa ggatgaccaa
    19441 tgtgcacatt caggatgttc atcagcacaa atgaagtggc atataagaag atgtgaatga
    19501 tgtagagaac cggcgctgca aacaaaaatg catattccag cggctccgta atcccggtaa
    19561 caaatgtggt cagcgcaccg gagagtaaaa ggcctttaat cagcgcctta cgttccggtt
    19621 ttgcttcctg atacatcgcc aacgcggcgg caggtaacgc aaacatcatg atcgggaaac
    19681 gacctgtcat aaacagcccc gccgtcaacg gagcaccgtc gcgcaattgg gcaaagaaca
    19741 ccggaatatc gcccgtcacc agttgcccgg atttggtcat gtagtcgcca aagttgtaat
    19801 aaaacggcac gttccagata tgatgcaggc caaaaggaat cagcgaacgt tcgccaacgg
    19861 cgtaaataaa ggccgcgaag ttcgcgttat gtccactggt caccagcgtt gaaagcgacg
    19921 ccagaccttt ttgtaccggt atccacagcc acggcaataa atagccgaca ataattgccg
    19981 ccacagccgt aataatcggt acaaagcgtt ttccaccgaa gaaaccaaga aactgaggca
    20041 attcaatatt gtggaagcgg gtatagagca gataaacaaa gatggcgaca atcagaccgc
    20101 caaacactcc cgtttgtaac gtcggtaccc cgaggatcat cgcataatca ccgttactgg
    20161 ctgcaacgga ctccgcagta atgccaagtt gcgttcccat cgtggcattc atgatcatgt
    20221 aactgataat cgctgaaagt gatgaagaac catcacctgt caggccaatc acaataccga
    20281 cacaaaacag caaaggaagg ttggcgaaaa tcaggccgcc gcaattcgcc agcagctcaa
    20341 tgttaaatga aatcccgatg gctaaaatca aacccgccgc cggaagaatg gcgattggta
    20401 acatcagagc agaagaaaat ttctgcaact tcttgaagtt aaacaaggat gttatttttt
    20461 tgctcatttt tattctcctg tagggtatcg agcaaataac ggcgacgact attccagatt
    20521 ggcgtggcgc ttaaacagtt cactttccgg cgcaccactt tcagcagcca tcttcatcac
    20581 taatgcatcg gcaatcacca gcaaagcttg ctcatacaac gacgccatcg gctgtgccga
    20641 gcggaaaaca gaatcttttt gatttttgga aggggcattg atttgcacga tgacgtcgac
    20701 aaactcggtg atagtggcgt gtcgattcgt ggttaacacc gccacagcgc cgccgagctg
    20761 acgtgctttt ttcgccagcg ccaccagttg tgctgtctca ccggaagcag aagaaacgat
    20821 aaacagatcg ccaggcccaa agttcggcgt aatggtttcc gtcaggaagt aaacctcttt
    20881 tcccatatgc atcaggcgca tggtgaaggc tttcatagaa aaaccggcgc gtcccaggcc
    20941 atagcagaaa acgcgctggc tttgctgaat agtgtcgatc aatttggtgc agtcatcctc
    21001 acggatagag tccttaacga aggttaattc attgatgatc tcagtgatgt acagctttgc
    21061 gtccatttca cacctcatga aataattttc tcaaacacaa aatctcatga aattttattt
    21121 cattccaatg catcagtatg aaatgtgaag ctagtcacaa gaaagatcat aggttgatat
    21181 gtttttcatt aaaaaacata gagatatcaa gtaattttta atatgtgatg gagaggcaga
    21241 tagaaaaaat ggcggaaatg acgaaattta tttcatgaga agggaataaa gaagattttc
    21301 ttaaacaggg tatgaactga tatctggaat ggtttacgca gtatgctggg aagacgtcgc
    21361 tgtaatgaga aaagaccggg tggtattacc acccggtttg gattttaccc ccgacgcaaa
    21421 ttctgcgccg cctgcaccat gttcgccagt gccgcgcggg tttctggcca gccgcgcgtt
    21481 ttcaggccac agtccgggtt gacccacaga cgctctgccg gaatgcgttt tgccgctttc
    21541 ttcagcaagg cttcaatcca ttccacgctc ggtacgtttg gcgagtgaat gtcatagacg
    21601 ccaggaccga tttcatttgg ataatcaaac tcttcaaacg actccagcaa ctccatgtcg
    21661 gaacgcgagg tttcgatggt gatgacgtct gcgtccaacg ccgcaatcga atccataatg
    21721 tcgttgaact cgcagtaaca catgtgagtg tggatttgtg tgtcatcttt cgccacggcg
    21781 gcgttgatac ggaaagcctc cacgccccac tggagatagg catcccagtc gctgcgacgc
    21841 agtggtaaac cttcgcgcaa tgccggttcg tcaatctgaa tgatgccaat tccagcggct
    21901 tccagatcgg ccacttcatc acgcagtgcc agcgcaatct gtttggcgat ggtttcacgg
    21961 ctgacatctt cacgcgggaa cgaccagcag agaatagtca ccgggccagt caacatccct
    22021 ttcaccggtt tatcagtcag ggattgcgca tattttgccc actccacggt aatcggtgcc
    22081 gggcggctaa cgtcaccaat aacaatcggt ggcttcacgc agcgggaacc gtagctctgt
    22141 acccaaccgt tttgcgtaaa gacaaagcca tccagatgct cgccaaagta ttccaccatg
    22201 tcattacgct cggcctcgcc atgtaccagc acatccagtc ccaaacgttc ctgctcaaca
    22261 atggcctgct tgatatgttc cgcaatgccc gtgcggtagt tattggcgtc gatattaccc
    22321 tttttaaaat ccagacgcag ggtacgaatc tccgtggttt gcgggaagga accaatcgtg
    22381 gtggtcggcc acgcgggcag tttaaaacgc gcacgctggg cttcagcacg cacttcatag
    22441 acattcgcac gctgactgtc ctgggcggtg atcgccgcca gacgcttttc tactgccgga
    22501 ttatgtacac gagtagagtg acgacgcgcc tgaatcggag cgctccactc tgccagagct
    22561 gccgtatcac cactgttcag cgcatcgcgc agcaatgcca gttcatgaca tttttgcagg
    22621 gcgaaggcaa accagctttt cacttctgca tcaagacgcg tttccacgct caggtcgatg
    22681 gggctgtgca gcagtgagca ggaagatgcc acccacaaat cacgtttgcc gacaatgtcc
    22741 ttaatttgcg catatttctc ggtaagatcg gcgcgccaga cgttacgacc attgataaga
    22801 cccgcagaca gcagccagtc agaaggcagg cgcttgtgca gttcagcaac gtcatcttta
    22861 ccatgtacaa gatcgacatg cagaccctga acaggcagcg cagtaatcgt gtcgaggttt
    22921 ggcgttacgc cttcaaaata ggtggtcagc agcagtttca cctggccctg gagcgcgtcg
    22981 taagcgggtt tgtatgcatc cagccacgcc tgcggcagtt ccagcactag cgcgggttcg
    23041 tcgatctgta cccactcaat gccgcgtttc gctagttctg ccagcacttg ctgataaacc
    23101 ggcagaatgt cgttcagcag gctcaggcga tcaaactgtt cacctttcac tttacccagc
    23161 cacaggtagg taaccggccc cagcagcaca ggtttcacct tgtggcccag cgccagcgcc
    23221 tcgtccactt cctccagcag ctgcgtccag gtcagtttga actgttggcc tttaacgaac
    23281 tccggcacca tgtagtgata gttggtgtta aaccatttgg tcatttccgc tgccgccgca
    23341 ggttcgccag tcggtgcacg tccacgacca atacggaaca gggtatcgat atctaccgaa
    23401 ccatcgttgt tctgatgacg ttgcggaaca ttacccagca gcagactggt tgtcagtaca
    23461 tgatcgtacc aggcaaaatc gcccaccggc agcaggtcga tacccgcttg cttttgttga
    23521 tcccagtgac gagcacgcaa ttcacgccct accgccagca gttcttcacg cgtggagttc
    23581 cccgcccaat aactctcttg cgcttttttc agctcgcgac gcaggccaac gcgagggaaa
    23641 ccgagggtgt gattaagaat tgtcattata tgccccttat ggaattttta gtatttagcc
    23701 gtccagatgt ttacacatcc ataattggcg gttactgtat attcctcaag cgcaaattat
    23761 tcatgccgaa gtgaaggact ttcatgatcg aagtaaaaca cctgaaaacg ctacaagcgt
    23821 tgcggaactg cggctcactc gcagccgctg cggcgacgtt gcatcaaacg caatccgccc
    23881 tgtctcacca gtttagcgat ctggaacaac gccttggctt ccggctattt gtgcgtaaaa
    23941 gccagccgct tcgctttaca ccgcagggag aaatcctgtt gcaactggca aatcaggtgc
    24001 tgccgcaaat tagccaggca ctgcaagcct gcaatgaacc gcagcagacg cgcctgcgca
    24061 ttgccataga gtgccatagc tgtattcagt ggctgacgcc cgcattagaa aatttccata
    24121 agaactggcc gcaggtggag atggatttta aatcgggcgt aacgtttgat ccgcagcctg
    24181 cgttgcaaca gggcgagctg gatctggtga tgacgtccga tattctgccg cgcagtggcc
    24241 tgcattattc gccgatgttc gactatgaag tacgtctggt gttagcacct gaccatccac
    24301 tggcggcaaa aacgcgtatt acaccggaag atctcgccag cgaaacgctg ttgatttatc
    24361 cggtgcagcg tagccgactg gatgtctggc ggcattttct tcagccagca ggcgtcagcc
    24421 cgtcactgaa aagcgtcgat aacaccttat tgttgattca gatggttgcc gcacggatgg
    24481 gtattgccgc actacctcat tgggtggtgg agagttttga acgccagggt ctggtggtca
    24541 ccaaaaccct gggcgaaggc ttgtggagcc gactgtacgc cgccgtgcgc gatggcgagc
    24601 agcgtcagcc gattacagaa gcgtttattc gttcagcgcg caatcacgcc tgcgatcatc
    24661 tgccgtttgt gaagagcgcg gagcgaccca cttacgatgc acccacagtg aggccaggat
    24721 caccagcgcg cctgtaataa acgttggcca gtgcggctgt tggtgccaga tagccaggtt
    24781 taccagcagc cctgccggaa cgtgcatatt attcataatg cccagcgttc cggcgtccac
    24841 ctgcgtcgcg ccgtagttcc acataaagta gccaatcccg gaagccacca cgccaagaaa
    24901 caccagaatg ccccattgca acgtggtttg cggcattttc tgcgcatttc ccagcaagaa
    24961 ccatgcaatc actgccacca ggaacgcgcc aagatagaac cacgcaaagg cgttatgctg
    25021 cggcatcggg cgagtttcca tcagacgttt gtaacccacc atgccgatgg caaaagtgat
    25081 attggagagt tgcaccagca acaagccagt ccagaaatgg tcggtgacct gatcatagcg
    25141 aataatcccg gcaccaatca ccgccaacaa ggcgctaaaa gcatagcccc agcgcagacg
    25201 gcgcttactc atgatgtcat aaatcagcgt gatgtagagc ggcgtcagta cggtgaacaa
    25261 cagcagttca gaaaccgtca ggtagagata ggcgcggaaa ctcagcatat acatcacacc
    25321 gagctgcatc gcgcccacca gcatatacag gccgaccgtt ttcaggctat tgccacgggt
    25381 acgcagaaac ggcagaaaaa caagtgccgc cagaccaacg cgcaccagca ccgcaaaata
    25441 gctatcgacg tgccccgcaa ggtactcgcc ataaaagcta aaggagaagg cccacagaat
    25501 cgtggtgatg ataagtagcg ccacaatgga aaactctttg attaacgagt atccattgta
    25561 gcgaagtatc aggttgacaa ctgaccaaat aaagaacgat tacgataaat agagcttacg
    25621 cagataatgc ggcactgcgt cttcggcgtt agtaccaatc acttccagct ctggatgcag
    25681 atctttcagc cgttgatgcg cgctgcccat aatgcagcct ttccccgcca tcgacagcat
    25741 ttcggcatcg ttcattccat cgccaaaggc aatacaatct tgcaggctgt aacccagttt
    25801 cttcgctacc gcttccaggg catggccttt tgaaacgccg ccagccatga cttccaggca
    25861 ggttaaggta gagaaactga cattgacgcg atcgccccag cgagcgttaa tcgcttgctc
    25921 cagtggcaga agtttttcat gggaatcgca ggtgaagaac actttgctga cgccttccgg
    25981 ctccagcaat cccggctcat acagcgcata attgaacacc gcttctttga aaaagcgcat
    26041 ctcttccggg cgatggcgat tcataaacca ttcgtcgtcg cgataaacgt tagtaatgat
    26101 gtccggattg tcgttgacta cgccaaacag atcgctggca atgtcgcgat ccaggttatg
    26161 agcaaaaatc aggttgccat ccagatcgtg aacgcgcgcg ccattggagg taatcatgta
    26221 agacttaatc tccagattat cgcgaatttg ccccacatca acgtggtgac gaccggtcgc
    26281 aaacacaaag ttgatgccgc gcgcggtgag cagcttcaga gtttctttgg cgtaagggga
    26341 taacgtatgg tcgggagaaa gtaacgtgcc atctaaatca gacgcaacaa cctggtacat
    26401 aagaaattta aacctctgta gagcggtttc cgctgggtga gttatgcctg ttgaaaaaat
    26461 caacgatagc gtggagcgcg actgagcgca ttgcgtcctt ttcaaaaagg atctcatggt
    26521 acgcaccttt aattaccaac ggccgtcctc cttcgacagg atggcccgca gcggtgcgta
    26581 gttcacaaaa acggtcgtgc atgcggttat ccaccacgcg ttcctcttca gcttgtaaga
    26641 gaagcgttgg cgtggcgtca tcacccgcac cggctaacac ctgttcgcca gccagaatac
    26701 tttcgcgtac ccaatggtag gtcggcccac cgacgcgaat cgttgggtca tcagcataga
    26761 aacgtaagtt acgtcgatat cgctgtctgc tgtgggtcag tacgttgata gcaaacggca
    26821 acgcgcgcca gcgcccggtg cctattgcat agccatcacg gaaacgtgga tgcgcttcgg
    26881 cccaattgag gatctgccgt gccataaatg acggcatacg aatcacgatc ccaaacattg
    26941 gcgcagttag cgcaatggcg tcacatacac ctggatggcg ttgcagaaat aatgtggaga
    27001 tcgcaccgcc catcgaatgt gccagtatat agcgtttacg ccacggaccg ggctgaacct
    27061 cctgttgcca gaatgccgcc agatcatcaa cataatcatt aaagcgatta acatgcccga
    27121 gatgtggatc ggctaacagg cgaccggaac gtccctgccc gcgatggtcg atgattaaaa
    27181 catcaaaccc cgaatggaac aggtcgtagg ccagttccgc atattttacg tagctctcaa
    27241 tacgccccgg gcagataact accacccggt catggtgctg tgcgcgaaaa cggacaaagc
    27301 gaaccggaat gtcatccaca ccagtaaact ctgcttcatc acgctgacgc cagaaatcag
    27361 tcagcggtcc catggtaaaa gcagcaaacg cgttttctct tgtttcccag tctttttgct
    27421 gctgaaacat cgggtaatct gcctcttaaa ccacgtaaaa tcgttttttt aagcgtgcct
    27481 gacacaacgc tgcgacagta gcgtattgtg gcacaaaaat agacacaccg ggagttcatc
    27541 atgaccttag aatggtggtt tgcctacctg ctgacatcga tcattttaag cctgtcgcca
    27601 ggctctggcg caatcaacac catgaccacc tcgctcaacc acggttatcg cggcgcggtg
    27661 gcgtctattg ctgggcttca gaccggactg gcgattcata ttgtgctggt tggcgtgggg
    27721 ttggggacgc tattttcccg ctcagtgatt gcgtttgaag tgttgaagtg ggcaggcgca
    27781 gcttacttga tttggcttgg gatccagcag tggcgcgccg ctggcgcaat tgatcttaaa
    27841 tcgctggcct ctactcaatc gcgtcgacat ttgttccagc gcgcagtttt tgtcaatctc
    27901 accaatccca aaagtattgt gtttctggcg gcgctatttc cgcaattcat catgccgcaa
    27961 cagccgcagc tgatgcagta tatcgtgctc ggcgtcacca ctattgtggt cgatattatt
    28021 gtgatgatcg gttacgccac ccttgctcaa cggattgctc tatggattaa aggaccaaag
    28081 cagatgaagg cgctgaataa gattttcggc tcgttattta tgctggtggg agcgctgtta
    28141 gcatcggcga ggcatgctta aaactggaat aaagctcacg taaattaatg tgcctcgaga
    28201 gattgttaca tccgcgctcg aggcatctcg taataagcgt aatctgttaa tttatttact
    28261 atttacttct ctttgttagt gccagaatgc cgccatattt cacccacgga tgatgaaaaa
    28321 tgacggaagc aacgacacca catgacgcaa tctttaaggc ttttttatcc cgaccagaaa
    28381 cggcccgtga ctttattgaa attcatctgc cgccttcttt agttaaactc tgcaatcttg
    28441 atacgctcca tctcgagtcc agcagttttg tagaggaaaa cctacgccag tattacaacg
    28501 acgtacttta ttcagtagag acgacgaaag ggtgcggata tatctatgtg ttgattgagc
    28561 atcaaagttc acctgatgaa aatatggcgt tccgtatgct tcgctatgct attgccacca
    28621 tgcagcggca tcttgaagcg ggacatgatt atctgcctct ggtgatcccc attctttttt
    28681 accagggaaa gcgtagccca tatccatggt caacaaactg gctcgatggt tttccggatc
    28741 cggacattgc acgcgatctc tattttcatg cttttccgct ggttgatatt acgctaattc
    28801 ctgatgacga aatcatgcaa caccgcagca tggccgcctt tacgctggta cagaagcata
    28861 tccgtcaacg ggatatgaca acgctgttag ataagttatc ccgcttaatg attctggggc
    28921 agatgagcgg acagcaaata cgcatgttga taaactacat ggcgctggta ggtgaagcac
    28981 aggatgtacg aacattagta catggtctgg cacaacgagt gcctcaacaa ggagaggaac
    29041 tgatgacttt agcggaagaa cttcggcgcg atgcccttct caatgtcgca aaagccatgc
    29101 tacagcgtgg ctttgatttg cagttgatta tggaaatgac cgggctttct caggaagacc
    29161 tttatcaatt gcaatcctga tgttattccc cctgatagcg tatcaggggg gaagcgctta
    29221 acgcgaaata atcaaatgaa tgccaaatcc ggcaaataac gccccggcaa aaccatcaat
    29281 ccacttcgcc agacgttgat aaccacagcg catttgcggc agagcaaaca ggctggcaac
    29341 gacggtaaac cacgccagtg tttcgacaat aatcaacgcg aaaatgcccc agcgttcggt
    29401 ggtgccgaca ttatcaccga caaacagcga gaacaccgaa ccaaagtaga taatcgcttt
    29461 aggattcgcg agattggtca gtaagccctt aagaaaactg cgcccgcttt tcgccagttc
    29521 gacttgtggc gcaggggcag aaacaacctc ttttttcagt gcaccacgta gcatctggta
    29581 acccatccag cagagataca ggccaccgcc caccataatc agcgtatgca gccaggccat
    29641 tttttcgata atcaaatgta ggccaagcaa cgcaatccca gcccaaacca ttacgccgca
    29701 ggtaatgccc agcacgccca tcatcgcttc tttacgggaa cgactaacag cggtctgaga
    29761 tacaaaaaag aaatcgggac cggggctcat aagcgccaca atgtgcacca tggcgacggt
    29821 gaggaataac atcaacatac attagactcg cggggggaaa cgtttacgga gtcttcatcc
    29881 tggcactttt ttatgctgct gactactctt cgtcgtcacc atcgacatgc gcacgaatca
    29941 gcgccataaa cggtttgcca aagcgttcca gcttgcgcat accaacgccg ttaacgctga
    30001 gcatttcgct ggcggtgatc ggcatctgtt cagccatctc aatcaaggta gcgtcgttaa
    30061 acaccacgta cggcgggaca ttgctttcat cggcaatcga tttacgcagt ttgcgtaatt
    30121 tggcgaacag tttgcgatca tagttgccgc cgaacgattt ctgcatcgct ttcggtttga
    30181 gcgccacgat acgcggcacg gcaagttgca aagaggattc gccgcgcagc accggacgcg
    30241 cagcctctgt cagttgtagg gcagaatgct gggcaatatt ttgcgtcacc aggccgaggt
    30301 gaatcagctg gcggatcacg ctcacccaat gttcatggct tttatcacgg cccatgccat
    30361 agactttcag tttgtcatga ccatagtcgc ggatacgctg attattagca ccgcgaatca
    30421 cttccaccac ataacccatc ccaaaccgct gattcacacg accaatggtg gaaagggcaa
    30481 tctgcgcatc ggttgaacca tcgtactgtt ttggcggatc gaggcagata tcgcagttcc
    30541 cgcacggctc ctgacgccct tcgccaaaat agttcagcaa taccaaacga cggcaagttt
    30601 gcgcttcagc aaacgcgccc atcgcattga gtttatgacg ttcgatatcc tgcaactgcc
    30661 cctgcggctt ctcttccaga caacggcgca gccacgccat atcagccgga tcgtaaaaca
    30721 gcatcgcttc cgcgggcagg ccatcacgcc cggcgcgtcc agtttcctga taataggatt
    30781 cgatattgcg cggaatatca aaatgcacca cgaagcgaac gttaggcttg ttgatgccca
    30841 tgccgaacgc caccgtcgcc accacaattt gcaggtcatc gcgctggaat ttttcctgca
    30901 catcagcgcg aacattattt tccagcccgg catgataggc cgccgcgcta attcccttgc
    30961 tttgcaggcg cgcagcggtg tcttctactt tcgcacgact attacagtaa ataatccccg
    31021 acttaccgcg ttgttcctgt acataacgca tcaactgatc gagcggtttg aatttctcca
    31081 tcagcatgta gcgaatattc ggacggtcaa aactgctgat ttgaatcagc ggatcgttca
    31141 gccccagcag gcgcacgata tcctggcgcg tggtgtcatc ggctgtggca gtcagcgcca
    31201 taaacggcag cgtcggaaaa cgctgacgca gctgaccgag ggcagcgtat tccgggcgga
    31261 aatcgtgacc ccattgggag atacagtgcg cctcgtcaac ggctaataac accggattcc
    31321 agtgcgccag atgctcaaga aagttatcca gcatcaggcg ttccggcgcg atataaagca
    31381 ggctgatttg cccggtgcga cagcctgtca tcacttcaag ttgctgctcg cgggtttgcg
    31441 tcgagttaag gcacgccgcc gccacgccgt tggcttgcag ttgatctacc tgatctttca
    31501 tcaacgaaat cagcggtgag acaaccacgg taaggccgtt tagcaataag gcagggattt
    31561 gatagcaaag ggattttccg ccaccagtgg gcatgacgac caggcaatcg cgaccggaaa
    31621 gtacggtgtc gataatctct tcctggccgg ggcgaaactg ttggtagcca aaggtttctt
    31681 gtaaaacctg tttagctccg gactccagat tcaacacttc cgcctgcgcc acattcaccc
    31741 cgattgcctg aaataaaaac aggcgctatt ttcagcgcct gcgcgagaaa ctgcaatgct
    31801 tttagtctct gagagggtaa tcctggatgc tggattccag atttgccaac cattcatcaa
    31861 aacaggtcgt ttagcataac tcccacacca acgcgggtct ggttgaagtt atagtcgatg
    31921 agcgattcgc cgtaaccgct gtaaacctga gtataaaggc gcacatgttt ggtgatcggg
    31981 tagcttaagc ctaactccgc gccgccgtaa ccggtgttcc agttgtactg ccctttcgcg
    32041 ctcagtaccg catcaccgag gtgatagccg attttaagct ggtagtaacc catatatttg
    32101 gtgatgtccg ggttatcgtc cgtattcccc accacatacc acggcttcac ctctaccaac
    32161 cagttaccgt tttctgccat caggcgggta taaaggcggt tccagctgcg ggaagtcggg
    32221 tctgaacgcc cgtttgagtc gtggttgtag cccatttcca catcgcgcag cgtccagcca
    32281 gcaaagttgt aatccgtggc aaaaccgagg aacaattgcg gttcgtagtt agtttcacga
    32341 aacggtgatg actcatcgct attagaaagc tgccaccagg atttctgtgt gtaggaggcg
    32401 cccagtacag agtttggccc caaaatccca cgccacagcg gaaacgccag gctcaactgg
    32461 aactttactt catccttacg cgcgttttcc gcccagtcgt aactggcaat cgcttcttta
    32521 ttcagatcgc tggtttgggt gtagatgatg tagttggtgt cataaggata aagggtgaac
    32581 ggattgtcat gctcctgcag catattggcg ataatactgc cacgcaccgc tggcgcgtca
    32641 tgcacctctt tcaccgttgc ctcttgtgca tatactgcca taggcaacat aaacaccggc
    32701 aacaaccagc cctgcagagt ccgcatcgct cgtgttctcc gtaacgaatt attgataagg
    32761 tgaatatttt tctgcgggct attttacata cttaactcca tagccgttag ttatcccttc
    32821 ctaaagtaga aaccaacaat aaataagcat aaaatcaaca tttcattaac taatgaagtg
    32881 taaggatgtt atgtctgccg tactgaccgc tgaacaagcc ctcaaattag tgggtgagat
    32941 gtttgtttat cacatgccat ttaaccgcgc attggggatg gaactggagc gttacgaaaa
    33001 agagttcgca cagctggcct ttaaaaatca gccgatgatg gtgggcaact gggcgcaaag
    33061 cattttacac ggcggggtca ttgcgtcggc gctggatgtc gccgcaggtc tggtgtgcgt
    33121 gggaagtacc ttaacccgcc acgaaaccat cagtgaagat gaactacgcc agcggctatc
    33181 gcggatgggg accattgatc ttcgcgtcga ttatctgcgc ccaggcagag gagagcgttt
    33241 tactgctacc agtagcctgt tgcgtgcagg caataaagtc gccgtcgccc gcgttgaatt
    33301 acacaatgaa gaacagcttt atattgccag tgccaccgcc acctatatgg taggttgaag
    33361 acataaaagc aggtaaactg ctgttaccaa ttaaaaatga gtattcccga tggatgcaaa
    33421 acaaacgcgg cagggcgtat tactcgctct tgccgcttat tttatttggg gtattgcgcc
    33481 agcgtacttc aaactgattt actacgtgcc cgccgatgag atcctgacgc atcgcgtgat
    33541 ctggtcgttt ttctttatgg tggtgctgat gagcatttgc cgccagtggt cctatttaaa
    33601 aacgctgatt cagacgccac agaaaatttt tatgctggca gtctctgccg tgctgattgg
    33661 tggcaactgg ctactgttta tctgggcggt gaacaatcac catatgctgg aagcgagcct
    33721 tggttacttt attaacccac tggtgaacat tgtgctgggg atgattttcc tcggcgagcg
    33781 attccgccgg atgcaatggc tggcggtgat tctggcgatt tgtggcgtgt tggttcagtt
    33841 gtggactttt ggttcactgc cgatcatcgc gctggggctg gcgtttagtt ttgctttcta
    33901 cggcctggtg cgcaagaaga ttgctgttga agcgcaaacc ggcatgttaa tcgaaactat
    33961 gtggttgctg cccgtggcgg cgatttacct gtttgctatt gccgacagct caaccagtca
    34021 tatggggcaa aacccgatgt cgctgaattt actgctgatc gccgccggta ttgtcaccac
    34081 cgtgccactg ttgtgtttta ctgcagctgc gacacgcctg cgtctctcaa cgttaggctt
    34141 tttccagtac attggtccga cgctgatgtt cctgctggct gtgacgtttt atggtgaaaa
    34201 accgggtgcc gataagatgg tgactttcgc ctttatttgg gtggcgctgg caatttttgt
    34261 gatggatgc
//
LOCUS       DAFGPF010000048        33939 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFGPF010000048 DAFGPF010000000
VERSION     DAFGPF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33939
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.048"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1025)
                     /locus_tag="LSX49_002524"
     CDS             complement(<1..1025)
                     /locus_tag="LSX49_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7168923.1"
                     /translation="MKINKILSSATLLYGMSMAMSVGSCATPVQTNLPGYTPGADIIS
                     VSPTRNQVDLIGDVVYSQIKGTRSVRQLHMSVLVPRTNDLKPAIIYYPGGGFMSSEHD
                     KFIEMRMALAEAGFVVAAVEYRTIPDTFPAPVEDGKAAIRYLREHASNYGIDPQRIGV
                     LGDSAGGWLAQMMGTTNGDKTFDKGDFLQQSSDVQAVATLYGISDLLNIGEGFPESVQ
                     EVHRSPAVTEALMINGPAFRNFAGAPITASKEKALNASPIGHMKGVKPPFLIMHGSKD
                     TLVSPEQSAKLFRMLKKNGDNAEYVLVEGAEHGDKTWYQPIIINRVVEWFTKNLGAPI
                     KTAPQQQ"
     gene            1375..1476
                     /locus_tag="LSX49_002525"
     CDS             1375..1476
                     /locus_tag="LSX49_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168924.1"
                     /translation="MRTHNPNSLLPSQMQKCTCVFLHLASDLCGGEA"
     gene            1473..1928
                     /gene="ybcN"
                     /locus_tag="LSX49_002526"
     CDS             1473..1928
                     /gene="ybcN"
                     /locus_tag="LSX49_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA base-flipping protein YbcN"
                     /protein_id="HBL7168925.1"
                     /translation="MNLPQDGIKLHRGNFIAIGQQIQPYLENGKCFRMVLKPWREKRS
                     LSQNALSHMWYSEISEYLISRGKSFATAAWVKDALKHTYLGYETKDLVDVVTGEITTI
                     QSLRHTSDLDTGEMYVFLCKVEAWAVNIGCHLTIPQSCEFQLLRDKQEA"
     gene            1928..2098
                     /locus_tag="LSX49_002527"
     CDS             1928..2098
                     /locus_tag="LSX49_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168926.1"
                     /translation="MATPLIRVMNGHIYRVPNRRKRKPELKPSEIPTLLGYTASLVDK
                     KWLRLAARRNHG"
     gene            2091..2381
                     /locus_tag="LSX49_002528"
     CDS             2091..2381
                     /locus_tag="LSX49_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HBL7168927.1"
                     /translation="MADLRKAARGRECQVRIPGVCNGNPETSVLAHIRLAGLCGTGIK
                     PPDLIATIACSACHDEIDRRTHFVDAGYAKECALEGMARTQVIWLKEGVIKA"
     gene            2378..2740
                     /locus_tag="LSX49_002529"
     CDS             2378..2740
                     /locus_tag="LSX49_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBL7168928.1"
                     /translation="MNTYCITLPWPPSNNRYYRHNRGRTHISAEGQAYRDNVARIIKN
                     AMLDIGLAIPVKISIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKM
                     PVTKGGKLELTITELGDE"
     gene            2737..2877
                     /locus_tag="LSX49_002530"
     CDS             2737..2877
                     /locus_tag="LSX49_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HBL7168929.1"
                     /translation="MMFESYMAERLRRRWVRLRLYRFPSSVLTDYRILKNYAKTLKGA
                     AA"
     gene            2874..3563
                     /locus_tag="LSX49_002531"
     CDS             2874..3563
                     /locus_tag="LSX49_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HBL7168930.1"
                     /translation="MNTQYLQYVREQLIVATADLSGATKGQLEAWLEHAQFDTGTYKR
                     KKPRILDEVTGRMITLDNPPISGKQLYAKGSSIALVSQVEFSTSSWRRAVLSLEEHQK
                     AWLLWSYSESVRWEHQVTITQWAWSEFKTLLGTRKIAGKTLERLKKLIWLAAQDVKNE
                     LAGRKTYEYQELASLVGVTSKNWSETFTERWVAMKHIFLQLDSQALLLLTKTRSKQKT
                     IFSQQDIAKLD"
     gene            3885..4190
                     /locus_tag="LSX49_002532"
     CDS             3885..4190
                     /locus_tag="LSX49_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL7168931.1"
                     /translation="MHEKESLAGAFWLVLLIIAGWGGLVRYLIDVKQSKATWSWINAL
                     AQIVVSGFTGVIGGLISIESGFSIYMILATAGISGAMGSVALTYFWERLTGVKNAKS"
     gene            4177..4653
                     /locus_tag="LSX49_002533"
     CDS             4177..4653
                     /locus_tag="LSX49_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HBL7168932.1"
                     /translation="MQNLNPQRKAFLDMLAWSEGTDNGRQPTRNHGYDVIVGGELFTD
                     YSDHPRKLVTLHPKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKER
                     GALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTLRESEV"
     gene            4870..5052
                     /gene="rzoD"
                     /locus_tag="LSX49_002534"
     CDS             4870..5052
                     /gene="rzoD"
                     /locus_tag="LSX49_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage lysis lipoprotein RzoD"
                     /protein_id="HBL7168933.1"
                     /translation="MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPPPPPAWIMQPPP
                     DWQTPLNGIISPSERG"
     gene            complement(5143..5436)
                     /gene="iss"
                     /locus_tag="LSX49_002535"
     CDS             complement(5143..5436)
                     /gene="iss"
                     /locus_tag="LSX49_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="increased serum survival lipoprotein Iss"
                     /protein_id="HBL7168934.1"
                     /translation="MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVS
                     GIGQKKTVDAAKICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ"
     gene            5917..6243
                     /locus_tag="LSX49_002536"
     CDS             5917..6243
                     /locus_tag="LSX49_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HBL7168935.1"
                     /translation="MKRRLLLLFLLSVLAVGCSQQKADEPRQLVTVYPRYPEYAAANY
                     IKGLVEVKFDIGADGTVTRIVFLRSEPHNLFRDEVVKAMAKWRFEKNRPCQGVKRQFI
                     FTPSRP"
     gene            6450..6632
                     /locus_tag="LSX49_002537"
     CDS             6450..6632
                     /locus_tag="LSX49_002537"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168936.1"
                     /translation="MLAVFQLVKNTCSRLLQCLQHAAAMRLAFTNHLSFLYQSLRELI
                     MEYQVNADVIGFGYAA"
     gene            7196..7741
                     /locus_tag="LSX49_002538"
     CDS             7196..7741
                     /locus_tag="LSX49_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HBL7168937.1"
                     /translation="MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSA
                     DVIKWYAERDAEIENEKLRREVEELRQASETDLQPGTIEYERHRLTRAQADAQELKNA
                     RDSAEVVETAFCTFVLSRIAGEIASILDGIPLSVQRRFPELENRHVDFLKRDIIKAMN
                     KAAALDELIPGLLSEYIEQSG"
     gene            7716..9641
                     /locus_tag="LSX49_002539"
     CDS             7716..9641
                     /locus_tag="LSX49_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HBL7168938.1"
                     /translation="MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFSNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHCMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLHVDEAINKTYT
                     RRNGAEMSVSRICWDIGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            9638..9844
                     /locus_tag="LSX49_002540"
     CDS             9638..9844
                     /locus_tag="LSX49_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family protein"
                     /protein_id="HBL7168939.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
     gene            9841..11442
                     /locus_tag="LSX49_002541"
     CDS             9841..11442
                     /locus_tag="LSX49_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL7168940.1"
                     /translation="MKTPTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRAWNPPGES
                     VDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDHIVGSFFRLSHRPSWRYLGIGEE
                     DARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTS
                     SSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQK
                     WTWIPRELPGGRASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKA
                     MYAATIESELDTQSAMDFILGANSKEQRDRLTGWIGEIAAYYAAAPVRLGGAKVPHLM
                     PGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANES
                     WAYFMGRRKFVASRQASQMFLCWLEEAIARRVVTLPSKARFSFQEARSAWGNCDWIGS
                     GRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFAQQVRETMERRAAGLKPP
                     AWAAAAFESGLRQSTEEEKSDSRAA"
     gene            11423..12742
                     /locus_tag="LSX49_002542"
     CDS             11423..12742
                     /locus_tag="LSX49_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HBL7168941.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLT
                     DAVSGDSLTAGEAPAALALSVDDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYS
                     GMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPDDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSATASQADVTGVVPAT
                     EGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETAR
                     RILAVAPQSAQARSDTALDRLMQGAPAPLAAGNLASDAVNDLLNTPV"
     gene            12752..13084
                     /locus_tag="LSX49_002543"
     CDS             12752..13084
                     /locus_tag="LSX49_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HBL7168942.1"
                     /translation="MTSKETFTHYQPLGNSDPAHTATAPGGLSAKAPAMTPLMLDTSS
                     RKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAF
                     AGTAISIV"
     gene            13140..14165
                     /locus_tag="LSX49_002544"
     CDS             13140..14165
                     /locus_tag="LSX49_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HBL7168943.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLV
                     DPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEEN
                     NITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKL
                     DTRRGSNSELETAVKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGN
                     TQARGLRTYGCIQDADAQLEGINASARYPKNWVTTGDPAREFTMIQSAPLMLLADPDE
                     FVSVQLA"
     gene            14207..14605
                     /locus_tag="LSX49_002545"
     CDS             14207..14605
                     /locus_tag="LSX49_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HBL7168944.1"
                     /translation="MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELEEELDDT
                     DETAGQDTPLSRENVLTGHENEVGSAQPDTVILDTSELVTVVALVTLHTDALHATRDE
                     PVAFVLPGTAFRVSAGVAAEMTERGLARMQ"
     gene            14617..14970
                     /locus_tag="LSX49_002546"
     CDS             14617..14970
                     /locus_tag="LSX49_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HBL7168945.1"
                     /translation="MADFDNLFDAAIVRADETIRGYMGTSATMTSGEQSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDTLTIGEENFWIDRISTDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            14982..15560
                     /locus_tag="LSX49_002547"
     CDS             14982..15560
                     /locus_tag="LSX49_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7168946.1"
                     /translation="MAIKGLEQAVENLSRISRTAVPGAAAMAINRVASSAISQSASQV
                     ARETKVRRKLVKERARLKRATVKNPQARIKVNRGDLPVIRLGNARVVLSRRRRRKKGQ
                     RSSLKGGDSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTT
                     AFKQNIERIRRERLPKELGYALQHQLRMVIKR"
     gene            15557..15952
                     /locus_tag="LSX49_002548"
     CDS             15557..15952
                     /locus_tag="LSX49_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7168947.1"
                     /translation="MKHTELRAAVLDALEKHDTGATLFDGRPAVFDEEDFPAVAVYLT
                     GAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDSWMESRIYPVMSDVPALSDLITSM
                     VASGYDYRRDDDAGLWSSADLTYVITYEM"
     gene            15960..16700
                     /locus_tag="LSX49_002549"
     CDS             15960..16700
                     /locus_tag="LSX49_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7168948.1"
                     /translation="MPVPNPVMPVKGAGTTLWVYKGNGDPYANPLSDVDWSRLAKVKD
                     LTPGELSAESYDDSYLDDEDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNE
                     GDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
                     TTGMTVTPASASVVKGQSTTLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVNG
                     VAAGKVNIPVVSGNGEFAAVAEITVTAS"
     gene            16716..17138
                     /locus_tag="LSX49_002550"
     CDS             16716..17138
                     /locus_tag="LSX49_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HBL7168949.1"
                     /translation="MFLKTESFEYNGVTVTLSELSALQRIEHLALMKRQAEPAGSDSN
                     RQVTVEDVIRTGAFLVAMSLWHNHPKKTQMPSMNEAVKQIEQEVLTTWPTEAISHAEN
                     VVYRLSGMYEFVVNNAPEQAEDAGPAEPVSAGKCSTVS"
     gene            17120..17554
                     /locus_tag="LSX49_002551"
     CDS             17120..17554
                     /locus_tag="LSX49_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HBL7168950.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPASPDVADMTEDDVMLMTVSEGIAGGVRYG"
     gene            17547..20108
                     /locus_tag="LSX49_002552"
     CDS             17547..20108
                     /locus_tag="LSX49_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL7168951.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTESDAKKTAAVV
                     EQSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQA
                     GLTADRMLVLSRAGQAAGLTFNQTSESLSALVKAGVSGEAQIASISQSVARFSSASGV
                     EVDKVAEAFGKLTTDPTSGLTAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAA
                     TKGFDDQTRRLKENMGTLETWADRTARAFKSMWDAVLDIGRPDTAQEMLIKAEAAFKK
                     ADDIWNLRKDDYFVNDEARARYWDDREKARLALEAARKKAEQQSQQDKNAQQQSDTEA
                     SRLKYTEEAQKAYERLQTPLEKYAARQEELNKALKDGKILQADYNTLMAAAKKDYETT
                     LKKPKQSGVKVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDLWKAESQ
                     FAVLEEAAQRRQLSVQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFA
                     QQQRAKRAAIDAKSRGLTDRQAEREATEQRLKEQYGDNPLALNNVMSEQKKTWAAEDQ
                     LRGNWMAGLKSGWSEWEESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQNWRSFTR
                     SVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFATGGFTG
                     TGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMADSRSQAS
                     GTFEQNNHVVINNDGTNGQIGPAALKAVYDMARKGARDEIQTQMRDGGLFSGGGR"
     gene            20105..20434
                     /locus_tag="LSX49_002553"
     CDS             20105..20434
                     /locus_tag="LSX49_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7168952.1"
                     /translation="MKTFRWKVKPGMDVASVPSVRKVRFGDGYSQRAPAGLNANLKTY
                     SVTLSVPREEATVLESFLEEHGGWKSFLWTPPYEWQQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            20434..21132
                     /locus_tag="LSX49_002554"
     CDS             20434..21132
                     /locus_tag="LSX49_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HBL7168953.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            21137..21880
                     /locus_tag="LSX49_002555"
     CDS             21137..21880
                     /locus_tag="LSX49_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7168954.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVVRTPKGERYFPCVNISGEPE
                     AYFRMSPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGEIHK
                     FRCVPHLTGRCFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRHGQNLYLDNLEAT
                     GLYQVPLSSAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWRASAFTGIYNDLAAASTFV"
     gene            21817..22419
                     /locus_tag="LSX49_002556"
     CDS             21817..22419
                     /locus_tag="LSX49_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HBL7168955.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLSD
                     GWYQVRIAGRDTGETELSARLNEPLANGAVIHIVPRLAGAKSGGVFQAVLGAAVMAVA
                     IWMPGVGIMASNLLFSLGASMTLGGVAQMLAPKPRTPRTQTTDNGKQNTYFSSLDNMV
                     AQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            22480..25962
                     /locus_tag="LSX49_002557"
     CDS             22480..25962
                     /locus_tag="LSX49_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HBL7168956.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQSPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLLNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTLKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKETIVDNGAHFDGEQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFMLRLTVAADDGSERLVSTARTTETTYRFRQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVEASARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITSGGNP
                     PTFSLTPDGRLSARNADISGNVNANSGTLNNVTINQNCRILGKLSANQIEGDIVKTVG
                     KAFPRNGSYASGTITVTVYDDQAFDRQIVVPPVLFRGGKHENFNSNNQQSYWYSTCKL
                     QVLKNGQEIFQQPATDVSRVFSSVIDMPAGHGHVTLTFNVSSYGANNWTPTTSISDLL
                     VVVMKKSTAGISIS"
     gene            26021..28042
                     /locus_tag="LSX49_002558"
     CDS             26021..28042
                     /locus_tag="LSX49_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HBL7168957.1"
                     /translation="MAVQISGVLKDGAGKPIQNCTIQLKAKRNSTTVVVNTVASENPD
                     EAGRYSMDVEYGQYSVALLVEGFPPSHAGTITVYEDSKPGTLNDFLGAATEDDVCPEA
                     LYRFEKMVEEAARNAEAASQSAAAAKKSETAAASSRNAAKTSETNAGNSAKAAASSKT
                     AAQNAATAAERSETNARASEEASADSEEASRRNAESAAENAGVATTKAREAAADATKA
                     GQKKDEALSAATRAEKAADRAEAAAEVTAEPCANIVPPLPDVWIPFNDSLDMITGFSP
                     SYKKIVIGDDEITMPGDKIVKFKRASTATYINKSGQLKLAEVDEPRFERDGLLIEGQR
                     TNYLRNSNKPDSWTVHSALNKTFGTDKQGFNYATVTPTESIVGTTGGYTVHGVVAADR
                     FPLASGECFTFSCRVKGAKARCRLRVSVIIGGTDTFSADSYLDLDTRIATVSGNTSLI
                     TAKAEQQGEWTYYEATYTANTDIDTVNCAFYMTNKISNETFYDDSTLTMTTPQIELGN
                     TASSFIVTTMPTTRASDVVTIPSQNNLSTRPFTVLCEVSRNWSTPPNVAPRIFDVGGH
                     SIDDNYLSLGFVATGKISANVGMVQPQIASDGERFIVGVRAKSDLSVNAICNGNYTTN
                     LNGKIFGVTATSYRFGGQTAAGTRHLFGHIRNFRVWFKELNDRQIKEAV"
     gene            28039..28317
                     /locus_tag="LSX49_002559"
     CDS             28039..28317
                     /locus_tag="LSX49_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168958.1"
                     /translation="MKDLTLKFPGNREFKSFLSSLDWEEDEDLQNKLLVDEIGFTYTE
                     TGVTEEGEPVCVRNDGYFVNIRILDDLFDVSVFSDYVVELETPLREWS"
     gene            28330..28623
                     /locus_tag="LSX49_002560"
     CDS             28330..28623
                     /locus_tag="LSX49_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168959.1"
                     /translation="MDISPLLHALCAVAAQILVGLFTGNWAYGAIAGCTFFIAREHTQ
                     AEYRWIEMFGHGKRMNMPWWGGFDPRAWDVASLMDFAVPVVACLLVWLLVNRG"
     gene            complement(28715..29572)
                     /gene="sitD"
                     /locus_tag="LSX49_002561"
     CDS             complement(28715..29572)
                     /gene="sitD"
                     /locus_tag="LSX49_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitD"
                     /protein_id="HBL7168960.1"
                     /translation="MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKGWALMG
                     DAMSHAVFPGIVLAWILGLPLATGAFVAGVFCAVATGYLKDNSRIKQDTVMGIVFSGM
                     FAAGLILYIAVKPDVHLDHILFGDMLGITIGDIIQTMIIAGLVTLVISVKWRDFLLFS
                     FDYQQAQVSGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRF
                     HIALLLATGISVIVSMTGVWLSFFIDSAPAPTIVVLFAVLFIMTFAVTSINARKKGNS
                     HTQDLLSPN"
     gene            complement(29569..30426)
                     /gene="sitC"
                     /locus_tag="LSX49_002562"
     CDS             complement(29569..30426)
                     /gene="sitC"
                     /locus_tag="LSX49_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitC"
                     /protein_id="HBL7168961.1"
                     /translation="MNVLLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGD
                     ALSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSMLFLNQRTRLKEDAIIGLIFSSFF
                     GLGLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFF
                     DENHARAIGLHPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFP
                     RLLMIAVTIGSVTSFLGAWVSYFLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRR
                     AHKALEDRS"
     gene            complement(30423..31250)
                     /gene="sitB"
                     /locus_tag="LSX49_002563"
     CDS             complement(30423..31250)
                     /gene="sitB"
                     /locus_tag="LSX49_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter ATP-binding
                     protein SitB"
                     /protein_id="HBL7168962.1"
                     /translation="MMQSAGIVVNDVTVTWRNGHTALRDASFTVPSGSIAALVGVNGS
                     GKSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLVAYVPQSEDVDWSFPVLVEDVVM
                     MGRYGHMGMLRIAKKRDRQIVTDALERVDMVNFRHRQIGELSGGQKKRVFLARAIAQQ
                     GDVILLDEPFTGVDVKTEAKIISLLRELRAEGKTMLVSTHNLGSVTTFCDYTVMVKGT
                     VLASGPTDTTFTAENLELAFSGVLRHVTLNGSEESIITDDERPFVAHRPSAVQREER"
     gene            complement(31250..32164)
                     /gene="sitA"
                     /locus_tag="LSX49_002564"
     CDS             complement(31250..32164)
                     /gene="sitA"
                     /locus_tag="LSX49_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter substrate-binding
                     protein SitA"
                     /protein_id="HBL7168963.1"
                     /translation="MHSIKKVTMLLGGLALTCSIAFQASATEKFKVITTFTIIADMAK
                     NVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMNLELWFQRFYQHLNG
                     VPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAQTYQ
                     RNADTYKAKITQTLAPLRKQITELPENQRWMVTSEGAFSYLARDLGLKELYLWPINAD
                     QQGTPQQVRKVVDIVKKNHIPAVFSESTISDKPARQVARETGAHYGGVLYVDSLSTEN
                     GPVPTYIDLLKVTTSTLVQGIKAGKREK"
     gene            32863..33621
                     /locus_tag="LSX49_002565"
     CDS             32863..33621
                     /locus_tag="LSX49_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7168964.1"
                     /translation="MKTLSGKEFRKLFNRYETGFYLSEFEYLKDFDPLFPECVGKELK
                     LGYKRKVDVWCEEDAALYAEFIATKERLKRGRLILKINQVWSRVYPAYIYAIEERINV
                     RAKGRESFKYETVQEKQCKLSIMLDGLKDLECEIAMISSEFEIEKHSMHYFYMIFDIE
                     RYINDCSYFVFSAAKVVKGVIQCIGYIDKNNKASCDEFYSGSYECLDDDQETLNYLNE
                     SCAEGIDADKDLIRKNELLALSLKELYQLLVSKK"
BASE COUNT         8452 a         8106 c         9679 g         7702 t
ORIGIN      
        1 ttttgttgtt ggggagctgt ttttataggc gctcccaggt ttttagtaaa ccactcaacg
       61 actctgttta taataattgg ctgataccat gtcttatcgc catgctcggc cccttctacc
      121 agcacgtact cagcgttatc accgttcttc ttcaacatcc tgaatagttt ggcgctttgc
      181 tcaggtgaaa ccagagtgtc tttgctacca tgcataataa gaaatggggg ttttactcct
      241 ttcatatgtc cgattggact ggcgtttagc gctttttctt ttgacgctgt gatgggggct
      301 cccgcaaaat ttctgaatgc agggccattg atcattaagg cttcggttac ggcaggagag
      361 cgatgaacct cctgcactga ttcagggaac ccctcgccaa tattcaacaa gtcagaaatc
      421 ccataaagtg tggcaactgc ctgaacatct gaggattgct gaagaaagtc acctttatca
      481 aaggttttgt caccatttgt agttcccatc atctgggcaa gccatccacc ggcagagtca
      541 cccagaactc cgattctttg aggatcaatc ccataattgc tggcatgctc tctcaggtaa
      601 cgtattgcag cttttccatc ctcaactggt gctggaaatg tatcaggaat tgttctgtat
      661 tctacagcgg ccacaacaaa accagcttct gccagagcca ttctcatttc aataaatttg
      721 tcatgttcag aagacatgaa tccgccgccg ggataataaa taatggctgg ttttaaatca
      781 tttgttcgcg ggacaagaac tgacatgtga agctgtctga cagaacgagt tccttttatc
      841 tgggaataaa caacatcacc aatgagatcg acctggtttc tggtcggtga aacactaatg
      901 atatctgcac ccggggtgta accaggaaga ttagtctgga caggtgttgc acaactcccg
      961 accgacatgg ccattgacat accatacaat agtgttgcag atgataatat cttgttaatt
     1021 ttcatgtttt acatgccttg acttatcgga tgaaattctc ttactaaatt taacggcagt
     1081 ttaatagccg tacaactcgt ggtagccagg gaaatatccc agtcgtggtt aaggttgtac
     1141 ttgacggcta ttatttcaac aatgcttaaa gtgagagctt aaggttatgc gtatgtttta
     1201 cagtccgagt agattctgac caatagcttc tttgtataat tctgtcagaa ataaatcttg
     1261 gcttgcatga agtttgagac cttatcttgt ttgattatga ataatcaatt cgccataatt
     1321 gtatcaccgg agcctgaaca actccggtga cttctgcgct aaacggggac gtttatgcgc
     1381 acacacaatc caaactctct tctcccttca cagatgcaga aatgcacctg cgtttttttg
     1441 catctagcgt ctgacctctg tggaggtgaa gcgtgaacct accacaagat ggcatcaaac
     1501 tgcatcgcgg taacttcatc gctatcggcc agcagatcca gccttatctg gagaacggaa
     1561 aatgctttcg catggtgctt aaaccgtggc gtgagaaacg cagtctttcc cagaatgcac
     1621 tcagccacat gtggtacagc gaaatcagtg aatacctcat cagcaggggg aaatcgttcg
     1681 ctaccgcagc atgggtaaaa gatgctctca aacacacata cctcggttat gaaaccaagg
     1741 acctggttga tgtcgtaacc ggcgaaatca ctactatcca gtcgttacgc catacctccg
     1801 atctcgatac cggagagatg tatgtcttcc tgtgtaaggt tgaagcctgg gcggtgaata
     1861 ttggctgcca cctgactatt ccgcagagct gcgagttcca gctgctgcgc gacaagcagg
     1921 aggcgtaatg gctacaccgc ttattcgtgt catgaacgga cacatctaca gagtaccaaa
     1981 tcgtcgtaag cgtaagcctg agctgaaacc atccgaaata ccaacactgc tcggatatac
     2041 cgccagcctg gttgataaaa aatggttgcg actggcagca aggaggaatc atggctgact
     2101 tgagaaaagc agcgcgtggt cgggaatgcc aggtaagaat ccctggcgta tgtaatggca
     2161 atcctgaaac gtcagtactg gcacatatcc ggctggctgg attgtgcggt accggtatca
     2221 aaccgccaga cctgattgcc accattgcat gttctgcctg ccacgacgaa atcgaccgtc
     2281 gcacgcattt tgttgacgct ggatatgcaa aagaatgtgc gctggaaggt atggcgagaa
     2341 cacaggttat ctggctgaaa gagggggtaa ttaaggcgtg aatacttact gcatcacact
     2401 accctggccg ccgagcaata atcgctatta ccgccataat cgcggacgca cgcatatcag
     2461 cgcagagggg caggcatacc gcgataatgt cgcccgaatc attaaaaacg caatgctgga
     2521 tatcggcctg gctattcctg tgaaaatcag cattgagtgc cacatgccgg atcgccgtcg
     2581 ccgtgacctt gataatctgc aaaaggccgc ttttgacgca ctcaccaaag caggtttctg
     2641 gctggatgat gctcaggtcg ttgattaccg cgttgtgaag atgcccgtta ccaaaggtgg
     2701 gaagctggag ctgactatca ctgaactggg agatgaatga tgtttgagtc ttatatggca
     2761 gaacgtcttc gccgccgctg ggtgcgcctg cgcttatatc gttttcctag ttctgttttg
     2821 accgattacc ggatactgaa gaattacgcc aaaacactga aaggagctgc cgcatgaata
     2881 cccaatattt acagtatgtc cgcgagcaac tcattgtggc taccgctgat ttgagcggag
     2941 caacgaaagg acagcttgaa gcctggctgg agcatgcaca atttgatact ggtacataca
     3001 aacgaaagaa gccgcgcatt ctggatgagg taactggcag gatgattacg ctggataatc
     3061 cgccgatttc cggtaagcag ttgtacgcaa aaggttcatc cattgcactg gtcagccagg
     3121 ttgagttctc aacctcgtca tggcgccgcg cggttctgtc tctcgaagaa catcagaaag
     3181 cgtggttgct gtggagttac agcgaaagtg ttcgctggga acatcaggtc accataacgc
     3241 agtgggcatg gagcgagttt aagactctgt tgggtaccag gaaaattgca ggtaaaacac
     3301 tggaacgttt gaagaagttg atctggctgg cggcacagga tgtgaagaac gagctggcag
     3361 ggcgtaagac ctatgaatac caggagctgg catcactggt gggagtgaca tcaaaaaact
     3421 ggtctgagac atttactgaa cgctgggttg caatgaagca catttttcta cagcttgata
     3481 gccaagcttt attgctttta acgaaaacac gttcaaaaca aaagaccata ttttcacagc
     3541 aagatattgc aaaactggat taaaaatcat atattttatg taaatctgat attttgccaa
     3601 tgttgtacgc actggcagta atccaaattc aagcccgagg tttaaagcct tgggcttttc
     3661 tgtttctgaa cggtgagtag ccttccaacc taccccagcc agggtgtctt cagctgttga
     3721 gttgatattg cttaaccctc tgttgccagc tacatgctgg cttttttatt ccaggcttgc
     3781 ggggagcatc aactccgtgc tttgtcgtta aattaccccg tgagcctgat ttctgacatt
     3841 taacgtcccg gccttttgtc ggcggcgaaa cattggctat tcatatgcac gaaaaagaga
     3901 gccttgccgg agcgttctgg ctcgttttgc tgatcatcgc aggttggggc ggtctggtcc
     3961 gctacctgat agatgtgaag cagagtaaag caacgtggag ttggataaat gctctggctc
     4021 aaatagtggt atcaggattc accggtgtta ttggtggcct gatcagcatc gaaagtggat
     4081 tcagtattta catgattctc gcgacagcgg ggattagtgg tgcgatgggt tcggttgcac
     4141 tgacgtactt ctgggaacga ctgacagggg tgaaaaatgc aaaatcttaa tcctcagcgt
     4201 aaagccttcc tcgatatgtt ggcgtggtca gaaggaacgg ataacgggcg acaaccgaca
     4261 cgtaaccacg gttatgatgt tattgttggc ggcgaactgt ttactgatta ctccgatcac
     4321 cctcgcaaac ttgtcacgct acaccccaaa ctcaaatcaa cagccgccgg acgttatcag
     4381 cttctttcac gctggtggga tgcttaccgt aaacagcttg gtttgaaaga cttctccccc
     4441 aaaagccagg acgcagtggc attacagcag attaaagagc gtggtgcttt accgatgatt
     4501 gatcgcggtg atatccgtca ggcaatcgac cgttgcagca atatctgggc ttcactgccg
     4561 ggcgctggtt atggtcagtt cgagcataag gctgacagcc tgattgcaaa attcaaagaa
     4621 gctggcggaa cgctcagaga gagtgaggta tgagcagaat aaccgcgatt atctccgctc
     4681 tggttatctg cgtcatcgtc tgcctttcat gggcggttaa tcattaccgc gataacgcga
     4741 ttacctacaa agcccagcgc gacaaaaatg ccagagaact gacgctggcg aacgcggcaa
     4801 ttactgacat acagatgcgt cagcgtgatg ttgctgcgct cgatgcaaaa tacacgaagg
     4861 agttagctga tgcgaaagct gaaaatgatg ctctgcgtga tgatgttgcc gctggtcgtc
     4921 gtcggttgca catcaaagca gtctgtcagt cagtgcgtga agccaccacc gcctccggcg
     4981 tggataatgc agcctccccc cgactggcag acaccgctga acgggattat ttcaccctca
     5041 gagagaggct gatcactatg caaaaacaac tggaaggaac ccagaagtat attaatgagc
     5101 agtgcagata gagctgccca tatcgatggg caactcatgc aattattgtg agcaatacac
     5161 acgcgcttcc agcggagtat aaatgcctaa agtaataaaa ccgagcaatc catttacgaa
     5221 tgtttgctgg gtttctgttt taacaacatt ttctgcacca ccacaaattt ttgctgcatc
     5281 gacagttttc ttctgcccaa ttcccgaaac gaagaaatga tgggtgatgg tttcctttgg
     5341 tgttactgct gtaggtttgt ttccaacagt aaacgtctgt tgagcacatc ctgtaataag
     5401 cattgccaga gcggcagaaa acaacatttt tttcatctta ttatcctgca ttgttaaaaa
     5461 cggcagaatc ctatgtgaca acaattaaac gatagttaaa tggattgatg aaaattaaaa
     5521 ctacacaggt gggctcagac tattggagga agttggggac actcagaatc ctgtggaatg
     5581 aaataaaccg gtctatccgt ccattaccct tttagctgcg ctgtatcgtc gccgtattcc
     5641 cgcattaacc atgaccgtag cccgacgggg aattccttct gcgtgagtgt gcgggaataa
     5701 ttaaaaacga tgcacaccgg gtttttaccg cgttaatgat tcgcgggttt atcccggtgc
     5761 gatggtggaa gaaacaggaa gctgtattac agaaagtgct actactgtat cccgatgcga
     5821 tgtatgtaat gtgagtcaga taatggcaca ggatgtggtg atgtggcagt ctggaacaca
     5881 ggatatattg tcagaataag acccgtagga ataaaaatga aaagacgcct tttactactt
     5941 tttctgttat ctgtcctggc agtgggatgc tcgcagcaaa aagctgatga gccccggcaa
     6001 ttagtgacgg tgtatccacg atatccggaa tatgctgcag caaattatat caaggggctg
     6061 gttgaggtta agttcgatat tggtgctgat gggactgtga cacggatcgt ttttctccgc
     6121 tcagagcctc ataatttgtt tcgtgatgaa gtggtgaagg ccatggcgaa atggcgattt
     6181 gaaaagaatc gcccctgtca gggagtgaag agacaattta tctttacgcc gtcacgtcct
     6241 tgatgcttcc aggtagagag gggctggaag caggagaaaa atgaaagagc cagcggttat
     6301 atttttgtca tggctgacga ggaatgatgg aagaaggcgt tgtatgccac acaacgcctc
     6361 actgttcatt tcttcttttt ctctggtgga acccgatgaa taagagttgc actggtttcc
     6421 gatgagatgg cgatatactc gggcaaagta tgctggcagt tttccaactg gtcaaaaata
     6481 cctgctctcg tctgttgcaa tgcctgcagc atgcggcggc aatgcgcctt gcttttacta
     6541 accatctttc cttcctctat cagtcgctgc gtgaactcat catggaatac caggtaaatg
     6601 cggatgttat cggttttggc tacgcagcat agtacaaaac ggacaggtgc atcccgggac
     6661 gggggaggcg tcacatgtcc ctgtgatggt tgttccgggt aatgtactgt gtggggcata
     6721 aaaatgtccg ataattttac tttctaccgc agttagttga ttcgttggtc ctggtagcac
     6781 attgggcgag gatttaaatg ccaggcaact gaaggatgat gtcgcaaggg agatagcgag
     6841 aatatttctg attttcattt gatgatgcct ctgtgtgaaa tgacggtaaa cgacgcactt
     6901 gtgccggcac ataatagcaa gcaccataat agatcagatt cgattcttgc tgtaagtgat
     6961 aattattctc gttttcgggt cctttccgtc gatccaacag gttacggggc ggcgacctcg
     7021 cgggttttcg ctatttatga aaattttccg gtttaaggcg tttccgttct tcttcgccgt
     7081 aacttaatgt ttttatttaa aacactccct gaaaagaaag gaaacgacag gtgctgaaaa
     7141 cgggcttttt ggcctctgtc gtttcctttc tctgtttttg tccgtggaat gaacaatgga
     7201 agtcaacaaa aagcagctgg ctgacatttt cggcgcgagt atccgtacta ttcagaactg
     7261 gcaggagcag ggaatgcccg ttctgcgagg cggtgggaag ggtaatgagg tgctttatga
     7321 ctctgccgac gtcataaaat ggtatgccga aagggatgct gaaattgaga acgaaaagct
     7381 gcgccgggag gttgaagaac tgcgacaggc cagcgagaca gatctccagc cagggactat
     7441 tgagtacgaa cgccatcgac ttacgcgtgc gcaggccgac gcacaggagc tgaaaaatgc
     7501 cagagactcc gctgaagtgg tggaaaccgc attctgtact ttcgtgctgt cgcggatcgc
     7561 aggtgaaatt gccagtattc tcgacgggat ccccctgtcg gtgcagcggc gttttccgga
     7621 actggaaaac cgacatgttg atttcctgaa acgggatatc atcaaagcca tgaacaaagc
     7681 agccgcgctg gatgaactga taccggggtt gctgagtgaa tatatcgaac agtcaggtta
     7741 acaggctgcg gcattttgtc cgcgccgggc ttcgctcact gttcaggccg gagccacaga
     7801 ccgccgttga atgggcggat gctaattact atctcccgaa agaatccgca taccaggaag
     7861 ggcgctggga aacactgccc tttcagcggg ccatcatgaa tgcgatgggc agcgactaca
     7921 tccgtgaggt gaatgtggtg aagtctgccc gtgtcggtta ttccaaaatg ctgctgggtg
     7981 tttatgccta ctttatagag cacaagcagc gcaacaccct tatctggttg ccgacggatg
     8041 gtgatgccga gaactttatg aaaacccacg ttgagccgac catccgcgat attccgtcgc
     8101 tgctggcgct ggctccgtgg tatggcaaaa agcaccggga taacacgctc actatgaagc
     8161 gtttttccaa tggtcgtggc ttctggtgcc tgggcggtaa agcggcaaaa aactaccgtg
     8221 aaaagtcggt ggatgtggcg ggttatgatg aacttgctgc ctttgatgag gatattgaac
     8281 aggaaggctc tccgacgttc cttggcgaca aacgtattga aggctcggtc tggccaaagt
     8341 ccatccgtgg ctccacgccc aaagtgagag gcacctgtca gattgagcgt gcagccagtg
     8401 aatccccgca ttgtatgcgt tttcatgttg cctgcccgca ctgcggggag gagcagtacc
     8461 ttaaatttgg cgataaagag acgccgtttg gcctcaaatg gacgccggat gatccctcca
     8521 gcgtgtttta tctctgcgaa cataatgcct gcgtcatccg ccagcaggag ctggacttca
     8581 ctgatgcccg ttatatctgc gaaaagaccg ggatctggac ccgtgatggc attctctggt
     8641 tttcgtcatc cggtgaagag attgagccgc cggacagcgt gacctttcac atctggacgg
     8701 cgtacagccc gttcaccacc tgggtgcaga ttgtcaaaga ctggatgaaa acgaaaggag
     8761 atacgggaaa acgtaaaacc ttcgtgaaca ccacgctcgg tgagacatgg gaagcgaaaa
     8821 tcggtgaacg tccggatgct gaagtgatgg cagagcggaa agagcattat tcagcgcccg
     8881 ttcctgaccg tgtggcttac ctgactgccg gtatcgactc ccagctggat cgctacgaaa
     8941 tgcgcgtatg gggatggggg ccgggtgagg aaagctggct gattgaccgg cagattatta
     9001 tgggccgcca cgacgatgaa cagacgctgc tgcatgtgga tgaggccatc aataaaacct
     9061 atacccgccg gaatggtgca gaaatgtcgg tatcccgtat ctgctgggat attggcggga
     9121 ttgacccgac catcgtgtat gaacgctcga aaaaacatgg gctgttccgg gtgatcccca
     9181 ttaaaggggc atccgtctac ggaaagccgg tggccagcat gccacgtaag cgaaacaaaa
     9241 acggggttta ccttacggaa atcggtacgg ataccgcgaa agagcagatt tataaccgct
     9301 tcacactgac gccggaaggg gatgaaccgc ttcccggtgc cgttcacttc ccgaataacc
     9361 cggatatttt tgatctgacc gaagcgcagc agctgactgc tgaagagcag gtcgaaaaat
     9421 gggtggatgg caggaaaaaa atactgtggg acagcaaaaa gcgacgcaat gaggcgctcg
     9481 actgcttcgt ttatgcgctg gcggcgctgc gcatcagtat ttcccgctgg cagctggatc
     9541 tcagtgcact gctggcgagc ctgcaggaag aggatggtgc agcaaccaac aagaaaacac
     9601 tggcagatta cgcccgtgcc ttatccggag aggatgaatg acgcgacagg aagaacttgc
     9661 cgctgcccgt gcggcactgc atgacctgat gacaggtaaa cgggtggcaa cggtacagaa
     9721 agacggacgg cgagtggagt ttacggccac ttccgtgtct gacctgaaaa aatacattgc
     9781 ggagctggag gtgcagaccg gcatgacaca gcgacgcagg ggacctgcag gattttatgt
     9841 atgaaaacgc ccaccattcc cacccttctg ggaccggacg gcatgacatc gctgcgtgaa
     9901 tatgccggtt atcacggcgg tggcagcgga tttggtgggc agttgcgggc gtggaaccca
     9961 ccgggtgaaa gtgtggatgc agccctgctg cccaacttta cccgtggcaa tgcccgcgca
    10021 gacgatctgg tacgcaataa cggctatgct gccaacgcca tccagctgca tcaggatcat
    10081 atcgtcgggt cttttttccg gctcagtcat cgcccaagct ggcgctatct gggcatcggg
    10141 gaggaagacg cccgtgcctt ttcccgcgag gttgaagcgg catggaaaga gtttgccgag
    10201 gatgactgct gctgcattga cgttgagcga aaacgcacgt ttaccatgat gattcgggaa
    10261 ggtgtggcca tgcacgcctt taacggtgaa ctgttcgttc aggccacctg ggataccagt
    10321 tcgtcgcggc ttttccggac acagttccgg atggtcagcc cgaagcgcat cagcaacccg
    10381 aacaataccg gcgacagccg gaactgccgt gccggtgtgc agattaatga cagcggtgcg
    10441 gcgctgggat attacgtcag tgaggacggc tatcctggct ggatgccgca gaaatggaca
    10501 tggatacccc gtgagttacc gggcggtcgt gcttcgttca ttcacgtctt tgaacccgtg
    10561 gaggacgggc agacccgcgg tgcaaatgtg ttttacagcg tgatggagca gatgaagatg
    10621 ctcgacacgc tgcagaacac gcagctgcag agcgccattg tgaaggcgat gtatgccgcc
    10681 accatcgaga gtgagctgga tacgcagtca gcgatggatt ttattcttgg cgcgaacagt
    10741 aaggagcagc gggacaggct gaccggctgg attggtgaaa ttgccgcgta ttacgccgca
    10801 gcaccggtcc ggctgggagg cgcaaaagtg cctcacctga tgccgggtga ctcactgaac
    10861 ctgcagacgg ctcaggacac ggataacggc tactccgtgt ttgagcagtc actgttgcgg
    10921 tatatcgctg ccgggctggg tgtctcgtat gagcagcttt cccggaatta cgcccagatg
    10981 agctactcca cggcacgggc cagtgcgaac gagtcgtggg cgtactttat ggggcggcga
    11041 aaattcgtcg catcccgtca ggcgagccag atgtttctgt gctggctgga agaggccatc
    11101 gctcgccgcg tggtgacgtt accttcaaaa gcgcgcttca gttttcagga agcccgaagt
    11161 gcctggggga actgcgactg gataggctcc ggtcgtatgg ccatcgatgg tctgaaagaa
    11221 gtacaggaag cggtgatgct gatagaagcc ggactgagta cctacgagaa agagtgcgca
    11281 aaacgcggtg acgactatca ggaaattttt gcccagcagg tccgtgaaac gatggagcgc
    11341 cgtgcagccg gtcttaaacc gcccgcctgg gcggctgcgg catttgaatc cgggctgcga
    11401 caatcaacag aggaggagaa gagtgacagc agagctgcgt aatctcccgc atattgccag
    11461 tatggccttt aatgagccgc tgatgcttga acccgcctat gcgcgggttt tcttttgtgc
    11521 gcttgcaggc cagcttggga tcagccgcct gacggatgcg gtatccggcg acagcctgac
    11581 tgccggagag gcacccgcgg cgctggcgtt atccgttgat gatgacggac cacgacaggc
    11641 ccgcagttat caggtcatga acggcatcgc cgtgctgccg gtgtccggca cgctggtcag
    11701 tcggacgcga gcgctgcagc cgtattcggg gatgaccggt tacaacggca ttatcgcccg
    11761 tctgcaacag gctgccagcg acccgatggt ggacggcatt ctgctcgata tggatacgcc
    11821 aggcgggatg gtggcagggg catttgactg cgctgacatc atcgcccgtg tgcgtgacat
    11881 aaagccggta tgggcgctgg ccaacgacat gaactgcagt gcaggtcagt tgcttgccag
    11941 cgccgcctcc cgacgtctgg tcacgcagac cgcccggaca ggctccatcg gcgtcatgat
    12001 ggctcacagt aattacggtg ctgcgctgga gaaacagggc gtggaaatca cgctgattta
    12061 cagcggcagc cataaggtgg atggcaaccc ctacagccat ctaccggatg atgtccggga
    12121 aacactgcag tcccggatgg atgcaacccg ccggatgttt gcacagaagg tgtcggcata
    12181 taccggcctg tccgtgcagg ctgtgctgga taccgaggct gcagtgtaca gcggtcagga
    12241 ggccattgat gccggactgg ctgatgaact tgttaacagt accgatgcga tcaccgtcat
    12301 gcgtgatgca ctggatgcac gtaaatcccg tctctcagga gggcgaatga ccaaagagac
    12361 tcaatcaaca actgtttcag ccactgcttc gcaggctgac gttactggcg tggtgccagc
    12421 gacggagggc gagaacgcca gcgctgcgca gccggacgtg aacgcgcaga tcaccgcagc
    12481 ggttgcggca gaaaacagtc gcattatggg gatcctcaac tgtgaggaag ctcacggacg
    12541 cgaagaacag gcacgcgtgc tggccgaaac ccctggtatg accgtggaaa cggcccgccg
    12601 cattctggca gttgcaccac agagtgcaca ggcgcgcagt gacactgcgc tggatcgtct
    12661 gatgcagggg gcaccggcac cgctggctgc aggtaacctg gcatctgatg ccgttaacga
    12721 tttgctgaac acaccagtgt aagggatgtt tatgacgagc aaagaaacct ttacccatta
    12781 ccagccgctg ggcaacagtg acccggctca taccgcaacc gcgcccggcg gattgagtgc
    12841 gaaagcgcct gcaatgaccc cgctgatgct ggacacctcc agccgtaagc tggttgcgtg
    12901 ggatggcacc accgacggtg ctgccgttgg cattcttgcg gttgctgctg accagaccag
    12961 caccacgctg acgttctaca agtccggcac gttccgttat gaggatgtgc tctggccgga
    13021 ggctgccagc gacgagacga aaaaacggac cgcgtttgcc ggaacggcaa tcagcatcgt
    13081 ttaactttac ccttcatcac taaaggccgc ctgtgcggct ttttttacgg gattttttta
    13141 tgtcgatgta cacaaccgcc cagctgctgg cggcaaatga gcagaaattt aagtttgatc
    13201 cgctgtttct gcgtctcttt ttccgtgaga gctatccctt caccacggag aaagtctatc
    13261 tctcacaaat tccgggactg gtaaacatgg cgctgtacgt ttcgccgatt gtttccggtg
    13321 aggttatccg ttcccgtggc ggctccacct ctgaatttac gccgggatat gtcaagccga
    13381 agcatgaagt gaatccgcag atgaccctgc gtcgcctgcc ggatgaagat ccgcagaatc
    13441 tggtggaccc ggcttaccgc cgccgtcgca tcatcatgca gaacatgcgt gacgaagagc
    13501 tggccattgc tcaggtcgaa gagatgcagg cagtttctgc cgtgcttaag ggcaaataca
    13561 ccatgaccgg tgaagccttc gatccggttg aggtggatat gggccgcagt gaggagaata
    13621 acatcacgca gtccggcggc acggagtgga gcaagcgtga caagtccacg tatgacccga
    13681 ccgacgatat cgaagcctac gcgctgaacg ccagcggtgt ggtgaatatc atcgtgttcg
    13741 atccgaaagg ctgggcgctg ttccgttcct tcaaagccgt caaggagaag ctggataccc
    13801 gtcgtggttc taattccgag ctggagacag cggtgaaaga cctgggtaaa gcggtgtcct
    13861 ataaggggat gtatggcgat gtggccatcg tcgtgtattc cggacagtac gtggaaaacg
    13921 gcgtcaaaaa gaacttcctg ccggacaaca cgatggtgct ggggaacact caggcacgcg
    13981 gtctgcgcac ctatggctgc attcaggatg cggacgcaca gctcgaaggc attaacgcct
    14041 ctgcccgtta cccgaaaaac tgggtgacca ccggcgatcc ggcgcgtgag ttcaccatga
    14101 ttcagtcagc accgctgatg ctgctggctg accctgatga gttcgtgtcc gtacaactgg
    14161 cgtaatcatg gcccttcggg gccattgttt ctctgtggag gagtccatga cgaaagatga
    14221 actgattgcc cgtctccgct cgctgggtga acaactgaac cgtgatgtca gcctgacggg
    14281 gacgaaagaa gaactggcgc tccgtgtggc agagctggaa gaggagcttg atgacacgga
    14341 tgaaactgcc ggtcaggaca cccctctcag ccgggaaaat gtgctgaccg gacatgaaaa
    14401 tgaggtggga tcagcgcagc cggataccgt gattctggat acgtctgaac tggtcacggt
    14461 cgtggcactg gtgacgctgc atactgatgc acttcacgcc acgcgggatg aacctgtggc
    14521 atttgtgctt ccgggaacgg cgttccgtgt ctctgccggt gtggcagccg aaatgacaga
    14581 acgtggcctg gccagaatgc aataacggga ggcgctgtgg ctgatttcga taacctgttc
    14641 gatgctgcca ttgtccgcgc cgatgaaacg atacgcgggt acatgggaac gtcagccacc
    14701 atgacatccg gtgagcagtc cggcgcagta atacgtggtg tttttgatga ccctgaaaat
    14761 atcagctatg ccggacaggg cgtgcgcgtt gaaggctcca gcccgtccct gtttgtccgg
    14821 actgatgatg tgcggcagct gcggcgcggc gacacgctga ccatcggtga ggaaaacttc
    14881 tggatagacc ggatttcgac ggatgatggc ggaagctgtc atctctggct tgggcgtggc
    14941 gtgccgcctg ccgttaaccg tcgtcgctga aggggggatg tatggccata aaaggtcttg
    15001 agcaggccgt tgaaaacctc agccgtatca gcagaacggc ggtgcccggt gccgccgcaa
    15061 tggccattaa ccgcgttgct tcatccgcga tatcgcagtc ggcgtcacag gttgcccgtg
    15121 agacaaaggt acgccggaaa ctggtaaagg aaagggccag gctgaaaagg gccacggtca
    15181 aaaatccgca ggccagaatc aaggttaacc ggggggattt gcccgtaatc aggctgggta
    15241 acgcgcgggt tgtcctgtcc cgacgcaggc gtcgtaaaaa ggggcagcgt tcatccctga
    15301 aaggtggcga cagcgtgctt gtggtgggaa accgtcgtat tcccggcgcg tttattcagc
    15361 aactgaaaaa tggccgatgg catgtcatgc agcgtgtggc cgggaaaaac cgttacccca
    15421 ttgatgtggt gaaaatcccg atggcagtgc cgctgaccac ggcgtttaaa cagaatattg
    15481 agcggatacg gcgtgaacgt cttccgaaag agctgggcta tgcgctgcag catcaactga
    15541 ggatggtaat aaagcgatga aacatacaga actccgtgca gccgtactgg atgcactgga
    15601 aaaacatgac accggggcga cgctttttga tggtcgcccc gctgtttttg atgaggagga
    15661 ttttccggca gttgccgttt atctcaccgg cgctgaatac acgggcgaag agctggacag
    15721 cgatacctgg caggcggagc tgcatattga agttttcctg cctgctcagg tgccggattc
    15781 agagctggat tcgtggatgg agtcccggat ttatccggtg atgagcgatg tcccggcact
    15841 gtcagatttg atcaccagta tggtggccag tggctatgac taccggcgcg acgatgatgc
    15901 gggcctgtgg agttcagccg atctgactta tgtcattacc tatgaaatgt gaggacgata
    15961 tgcctgtacc aaatccagta atgccggtga aaggggccgg gaccaccctg tgggtttata
    16021 aggggaacgg tgacccttat gcgaacccgc tttcagacgt tgactggtcg cgtctggcta
    16081 aagttaaaga cctgacgccc ggcgaactga gcgctgagtc ctatgacgac agctatctcg
    16141 atgatgaaga tgcggactgg actgcgaccg ggcaggggca gaaatctgcc ggagatacca
    16201 gcttcacgct ggcgtggatg cccggagagc aggggcagca ggcgctgctg gcgtggttta
    16261 atgaagggga tacccgtgcc tataaaatcc gcttcccgaa cggcacggtc gatgtgttcc
    16321 gcggctgggt cagcagtatc ggtaaggcgg tgacggcgaa ggaagtgatc acccgcacgg
    16381 tgaaagtcac caacgtggga cgtccgtcga tggcagaaga tcgcagcacg gtgacggcga
    16441 caaccggcat gacggtgaca cccgccagtg cttccgtagt gaaagggcag agcactacgc
    16501 tgaccgtggc attccagccg gagggcgcaa ccgacaagag cttccgtgcg gtgtctgcgg
    16561 ataaaacaaa agccaccgtg tcggtcagcg gtatgaccat caccgtgaac ggcgttgctg
    16621 caggcaaggt caacattccg gttgtatccg gtaatggtga gtttgctgcg gttgcagaaa
    16681 tcaccgtcac cgccagttaa tccggagagt cagcgatgtt cctgaaaacc gaatcatttg
    16741 aatataacgg cgtgaccgtc acgctttctg aactgtcagc cctgcagcgt attgagcatc
    16801 ttgccctgat gaaacggcag gcagaaccgg cgggatccga cagcaaccgg caggttactg
    16861 tggaagacgt catcagaacc ggcgcgtttc tggtggcgat gtccctgtgg cataaccatc
    16921 cgaagaagac gcagatgccg tccatgaatg aagccgttaa acagattgag caggaagtgc
    16981 ttaccacctg gcccacagag gcaatttctc atgctgaaaa cgtggtgtac cggctgtccg
    17041 gtatgtatga gtttgtggtg aataatgccc ccgaacaggc agaggacgcc gggcctgcag
    17101 agcctgtttc tgcgggaaag tgttcgacgg tgagctgagt tttgccctga aactggcgcg
    17161 tgagatgggg cgacccgact ggcgtgccat gcttgccggg atgtcatcca cggagtatgc
    17221 cgactggcac cgcttttaca gtacccatta ttttcatgat gttctgctgg atatgcactt
    17281 ttccgggctg acgtacaccg tgctcagcct gtttttcagc gatccggata tgcatccgct
    17341 ggatttcagt ctgctgaacc ggcgcgaggc tgacgaagag cctgaagatg atgtgctgat
    17401 gcagaaagcg gcagggcttg ccggaggtgt ccgctttggc ccggacggga atgaagttat
    17461 ccccgcttcc ccggatgtgg cggacatgac ggaggatgac gtaatgctga tgacagtatc
    17521 agaagggatc gcaggaggag tccggtatgg ctgaaccggt aggcgatctg gtcgttgatt
    17581 tgagtctgga tgcggccaga tttgacgagc agatggccag agtcaggcgt catttttccg
    17641 gtacggaaag tgatgcgaaa aaaacagcgg cagtcgttga acagtcgctg agccgacagg
    17701 cgctggctgc acagaaagcg gggatttccg tcgggcagta taaagccgcc atgcgtatgc
    17761 tgcctgcaca gttcaccgac gtggccacgc agcttgcagg cgggcaaagt ccgtggctga
    17821 tcctgctgca acaggggggg caggtgaagg actccttcgg cgggatgatc cccatgttca
    17881 gggggcttgc cggtgcgatc accctgccga tggtgggggc cacctcgctg gcggtggcga
    17941 ccggtgcgct ggcgtatgcc tggtatcagg gcaactcaac cctgtccgat ttcaacaaaa
    18001 cgctggtcct ttccggcaat caggcgggtc tgacggcaga tcgtatgctg gtcctgtcca
    18061 gagccgggca ggcggcaggg ctgacgttta accagaccag cgagtcactc agcgcactgg
    18121 ttaaggcggg ggtaagcggt gaggctcaga ttgcgtccat cagccagagt gtggcgcgtt
    18181 tctcctctgc atccggcgtg gaggtggaca aggtcgctga agccttcggg aagctgacca
    18241 cagacccgac gtcggggctg acggcgatgg cacgccagtt ccataacgtg acggcggagc
    18301 agattgcgta tgttgctcag ttgcagcgtt ccggcgatga agccggggca ttgcaggcgg
    18361 cgaacgaggc cgcaacgaaa gggtttgatg accagacccg ccgcctgaaa gagaacatgg
    18421 gcacgctgga gacctgggca gacaggactg cgcgggcatt caaatccatg tgggatgcgg
    18481 tgctggatat tggtcgtcct gataccgcgc aggagatgct gattaaggca gaggctgcgt
    18541 ttaagaaagc agacgacatc tggaatctgc gcaaggatga ttattttgtt aacgatgaag
    18601 cgcgggcgcg ttactgggat gatcgtgaaa aggcccgtct tgcgcttgaa gccgcccgaa
    18661 agaaggctga acagcagagt caacaggaca aaaatgcgca gcagcagagc gataccgaag
    18721 cgtcacggct gaaatatacc gaagaggcgc agaaggctta cgaacggctg cagacgccgc
    18781 tggagaaata tgccgcccgt caggaagaac tgaataaggc cctgaaagac ggaaaaatcc
    18841 tgcaggcaga ttacaacacg ctgatggcgg cagcgaaaaa ggactatgaa acgacactga
    18901 aaaagccgaa gcagtccggc gtgaaggtgt ctgcgggcga tcgtcaggaa gacagtgctc
    18961 atgctgccct gctgacgctt caggctgaac tccggacgct ggagaagcat gccggagcaa
    19021 atgagaaaat cagccagcag cgccgggatt tgtggaaggc ggagagtcag ttcgcggtac
    19081 tggaggaggc ggcgcaacgt cgccagctgt ctgtacagga gaaatccctg ctggcgcata
    19141 aagatgagac gctggagtac aaacgccagc tggctgcact tggcgacaag gttacgtatc
    19201 aggagcgcct gaacgcgctg gcgcagcagg cggataaatt cgcacagcag caacgggcaa
    19261 aacgggccgc cattgatgcg aaaagccggg ggctgactga ccggcaggca gaacgggaag
    19321 ccacggaaca gcgcctgaag gaacagtatg gcgataatcc gctggcgctg aataacgtca
    19381 tgtcagagca gaaaaagacc tgggcggctg aagaccagct tcgcgggaac tggatggcag
    19441 gcctgaagtc cggctggagt gagtgggaag agagcgccac ggacagtatg tcgcaggtaa
    19501 aaagtgcagc cacgcagacc tttgatggta ttgcacagaa tatggcggcg atgctgaccg
    19561 gcagtgagca gaactggcgc agcttcaccc gttccgtgct gtccatgatg acagaaattc
    19621 tgcttaagca ggcaatggtg gggattgtcg ggagtatcgg cagcgccatt ggcggggctg
    19681 ttggtggcgg cgcatccgcg tcaggcggta cagccattca ggccgctgcg gcgaaattcc
    19741 attttgcaac cggaggattt acgggaaccg gcggcaaata tgagccagcg gggattgttc
    19801 accgtggtga gtttgtcttc acgaaggagg caaccagccg gattggcgtg gggaatcttt
    19861 accggctgat gcgcggctat gccaccggcg gttatgtcgg tacaccgggc agcatggcag
    19921 acagccggtc gcaggcgtcc gggacgtttg agcagaataa ccatgtggtg attaacaacg
    19981 acggcacgaa cgggcagata ggtccggctg ctctgaaggc ggtgtatgac atggcccgca
    20041 agggtgcccg tgatgaaatt cagacacaga tgcgtgatgg tggcctgttc tccggaggtg
    20101 gacgatgaag accttccgct ggaaagtgaa acccggtatg gatgtggctt cggtcccttc
    20161 tgtaagaaag gtgcgctttg gtgatggcta ttctcagcga gcgcctgccg ggctgaatgc
    20221 caacctgaaa acgtacagcg tgacgctttc tgtcccccgt gaggaggcca cggtactgga
    20281 gtcgtttctg gaagagcacg ggggctggaa atcctttctg tggacgccgc cttatgagtg
    20341 gcagcagata aaggtgacct gcgcaaaatg gtcgtcgcgg gtcagtatgc tgcgtgttga
    20401 gttcagcgca gagtttgaac aggtggtgaa ctgatgcagg atatccggca ggaaacactg
    20461 aatgaatgca cccgtgcgga gcagtcggcc agcgtggtgc tctgggaaat cgacctgaca
    20521 gaggtcggtg gagaacgtta ttttttctgt aatgagcaga acgaaaaagg tgagccggtc
    20581 acctggcagg ggcgacagta tcagccgtat cccattcagg ggagcggttt tgaactgaat
    20641 ggcaaaggca ccagtacgcg ccccacgctg acggtttcta acctgtacgg tatggtcacc
    20701 gggatggcgg aagatctgca gagtctggtc ggcggaacgg tggtccggcg taaggtttac
    20761 gcccgttttc tggatgcggt gaacttcgtc aacggaaaca gttatgccga tccggagcag
    20821 gaggtgatca gccgctggcg cattgagcag tgcagcgaac tgagcgcggt gagtgcctcc
    20881 tttgtactgt ccacgccgac ggaaacggat ggcgctgttt ttccgggacg tatcatgctg
    20941 gccaacacct gcacctggac ctatcgcggt gacgagtgcg gttatagcgg tccggctgtc
    21001 gcggatgaat atgaccagcc aacgtccgat atcacgaagg ataaatgcag caaatgcctg
    21061 agcggttgta agttccgcaa taacgtcggc aactttggcg gcttcctttc cattaacaaa
    21121 ctttcgcagt aatcccatga cacagacaga atcagcgatt ctggcgcacg cccggcgatg
    21181 tgcgccagcg gagtcgtgtg gcttcgtggt gagaacgccg aagggggaaa gatattttcc
    21241 ctgcgtgaat atctccggtg agccggaggc gtatttccgg atgtcgccgg aggactggct
    21301 gcgggcagag atgcagggtg agattgtggc gctggtccac agccaccccg gtggtctgcc
    21361 ctggctgagt gaggctgaca ggcggctgca ggtgcagagc gatttgccgt ggtggctggt
    21421 ctgccggggt gagattcata aattccgctg tgtgccgcat cttaccgggc ggtgctttga
    21481 gcacggggtg acggactgtt acacgctgtt ccgggatgct tatcatctgg cggggattga
    21541 gatgccggat tttcatcgcg gggatgactg gtggcgtcac ggtcagaatc tctatctgga
    21601 taatctggag gccacagggc tgtatcaggt gccgttgtca tcagcacaac cgggcgatgt
    21661 gctgctgtgc tgttttggtt catcggtgcc gaatcatgcc gccatttact gtggtgatgg
    21721 cgagctgctg caccatattc ctgaacaact gagcaaacga gagaggtata ccgacaaatg
    21781 gcagcgacgc acacactccc tctggcgtca ccgggcatgg cgcgcatctg cctttacggg
    21841 gatttacaac gatttggccg ccgcatcgac cttcgtgtga aaacgggggc tgaagccatc
    21901 cgggcgctgg ccacacagct cccggcgttt cgtcagaaac tgagcgacgg ctggtatcag
    21961 gtacggattg ccgggcgtga tacaggtgaa acggaattat cagcccgtct taatgaaccg
    22021 ctggcaaatg gtgctgtgat ccatatcgtg ccgcgtctgg caggagccaa aagtggcggt
    22081 gtgtttcagg ctgtgctggg ggcggctgtt atggcggttg ctatatggat gccgggggta
    22141 ggaattatgg cgagtaatct gctgttttct ctcggtgcca gtatgacgct tggcggtgtt
    22201 gcacagatgc tggcccctaa acccagaacc ccccgcacac agacaacgga taacggcaaa
    22261 cagaacacct atttttcttc actggataat atggttgccc agggcaatgt tctgcccgtt
    22321 ctgtacggtg aaatgcgcgt gggatcacgt gtggtatctc aggagatcag cacagcagat
    22381 gaaggtgatg gtggtcaggt tgtggtgatt ggtcgctgat gaaaaacgtt ttatgtgaaa
    22441 ccgcctccgg gcggttttat cgtttatgga gcatgacgaa tgggtaaagg cagcagtaag
    22501 gggcataccc cgcgcgaagc gaaggacaac ctgaagtcca cgcagctgct gagtgtgatc
    22561 gatgccatca gcgaagggcc ggttgaaggt ccggtggatg gattaaaaag cgtgctgctg
    22621 aacagtacgc cggtgctgga cagtgagggg aataccaata tatccggcgt cacggtggtg
    22681 ttccgggccg gtgagcagga gcagtcaccg ccggagggat ttgaatcctc cggctccgag
    22741 acggtgctgg gtacggaagt gaaatatgac acgccgatca cccggaccat cacgtcggca
    22801 aacatcgacc gtctgcgctt taccttcggt gtacaggcac tggtggaaac cacctcaaag
    22861 ggagacagga atccgtcgga agttcgcctg ctggttcaga tacagcgtaa cggtggctgg
    22921 gtgacggaaa aagacatcac cattaagggc aaaaccacct cgcagtatct ggcctcggtg
    22981 gtggtggata acctgccgcc gcgcccgttt aatatccgga tgcgcaggat gacgccggac
    23041 agcaccacag accagctgct gaacaaaacg ctctggtcgt catacaccga aatcatcgat
    23101 gtgaaacagt gctacccgaa cacggcactg gttggcgtgc aggtggactc ggagcagttc
    23161 ggcagccagc aggtgagccg taattatcat cttcgcgggc gcattctgca ggtgccgtcg
    23221 aactataacc cgcagacgcg gcaatacagc ggtatctggg acggaacgtt aaaaccggca
    23281 tacagcaaca acatggcctg gtgtctgtgg gatatgctga cccatccgcg ctacggcatg
    23341 gggaaacgtc ttggtgcggc ggatgtggat aaatgggcgc tgtatgtcat cggccagtac
    23401 tgcgaccagt cggtgccgga cggctttggc ggcacggagc cgcgcattac ctgtaatgcg
    23461 tacctgacca cacagcgcaa ggcgtgggat gtgctcagtg atttctgctc ggcgatgcgc
    23521 tgtatgccgg tatggaacgg gcagacgctg acgttcgtgc aggaccgacc atcagataag
    23581 gtgtggacct ataaccgcag taatgtggtg atgccggatg atggcgcgcc gttccgctac
    23641 agcttcagcg ccctgaagga ccgccataat gccgttgagg tgaactggat tgacccggat
    23701 aacggctggg agacggcgac agagctcgtg gaggatacgc aggccattgc ccgttacggc
    23761 cgtaacgtca cgaagatgga tgcctttggc tgtaccagcc gggggcaggc acaccgcgcc
    23821 gggctgtggc tgattaaaac ggagctgctg gaaacgcaga ccgtggactt cagcgtgggt
    23881 gctgaagggc ttcgccatgt accgggggat gtcattgaaa tctgcgatga tgactatgcc
    23941 ggtatcagca ccggtggtcg tgtgctggcg gtgaacagcc agacccggac gctgacgctc
    24001 gaccgtgaaa tcacgctgcc atcctccggt accacgctga taagcctggt tgacggaagt
    24061 ggcaatccgg tcagcgtgga ggttcagtcc gtcaccgacg gcgtgaaggt gaaagtgagc
    24121 cgtgttcctg acggtgttgc tgaatacagc gtatgggggc tgaagctgcc gacgctgcgc
    24181 cagcgactgt tccgctgcgt gagtatccgt gaaaacgacg acggcacgta tgccatcacc
    24241 gccgtgcagc atgtgccgga aaaagagacc atcgtggata acggggcgca ctttgacggc
    24301 gaacagagtg gcacggtgaa tggtgtcacg ccgcccgcgg tgcagcacct gaccgcagaa
    24361 gtcaccgcag acagcgggga atatcaggtg ctggcgcgat gggacacacc gaaggtggtg
    24421 aagggggtga gctttatgct tcgcctgacc gtggcagcgg atgacggcag tgagcggctg
    24481 gtcagcacgg ccaggacgac ggaaaccaca taccgcttca ggcaactggc gctggggaac
    24541 tacaggctga cagtccgggc ggtaaatgcg tgggggcagc agggggatcc ggcgtcggta
    24601 tcgttccgga ttgccgcacc ggcagcgcca tcgcggattg agctgacgcc gggctatttt
    24661 cagataaccg caacgccgca tcttgccgtt tatgatccga cggtacagtt tgagttctgg
    24721 ttctcggaaa agcggattgc ggatatcagg caggttgaag ccagcgcgcg ttatcttggt
    24781 acggcgctgt actggatagc cgccagtatc aatatcaaac cgggccatga ttattatttt
    24841 tacattcgca gtgtgaacac cgttggcaaa tcggcatttg tggaggctgt tggccagccg
    24901 agtgatgatg catccggcta tctggatttt ttcaaaggag agatagggaa aacccatctg
    24961 gctcaggagt tgtggacgca gattgataac ggtcagcttg cgcctgacct ggctgaaatc
    25021 aggacgtcca ttacggatgt cagcaatgaa atcacgcaga ccgtcaataa gaaactggaa
    25081 gaccagagtg cagcgatcca gcagatacag aaggttcagg ttgatacaaa taataacctg
    25141 aacagcatgt gggctgtgaa gctgcagcag atgcaggacg gacgccttta tatcgcgggt
    25201 attggtgccg gtattgagaa tacccctgac ggtatgcaga gtcaggtgct gctggcggcg
    25261 gacaggattg cgatgattaa tcctgcgaat ggcaatacaa agccgatgtt tgttgggcag
    25321 ggcgatcaga tattcatgaa cgaagtgttc ctgaaatatc tgacggctcc caccattacc
    25381 agcggtggca atcccccaac gttttcactg acacctgatg gtcgactttc tgcgagaaat
    25441 gcggatatca gcggtaacgt gaatgcgaac tccgggacgc tcaataatgt cacgattaac
    25501 cagaactgtc ggattctggg aaaactgtca gctaaccaga ttgaaggtga tattgtcaaa
    25561 acggtgggaa aagcctttcc gagaaatggc agttatgcca gcggtacaat aacggtcact
    25621 gtgtacgatg accaggcttt tgaccgtcag atagtcgtcc cccccgttct gtttcgcggt
    25681 ggtaagcatg aaaacttcaa cagcaacaac caacagtcat actggtattc aacctgtaag
    25741 ctgcaggtgc tgaagaacgg acaggaaatc tttcagcaac ccgcgacgga tgtcagcagg
    25801 gtattttcat cagtcattga tatgcctgcc ggacacggcc atgtcaccct gactttcaat
    25861 gtttcttcat atggtgcaaa taactggacg ccaacgacca gtatcagcga ccttcttgtt
    25921 gtcgtgatga agaaatcaac agccggcatc agtatcagtt gaattttaaa acccaaattc
    25981 gggcaccaga aatggtgcct tttttatttg tggagtgaat atggcagtac agatttcagg
    26041 tgtgctgaaa gacggtgcag gaaaaccgat acagaactgc accattcagc tcaaagcaaa
    26101 acgtaacagc accacagttg tggtgaacac ggtggcctca gaaaatccgg atgaagccgg
    26161 acgttacagc atggatgttg agtatggcca gtacagcgtc gccctgctgg ttgaaggttt
    26221 tccgccttca catgccggga ccatcaccgt gtatgaggat tctaagccgg ggacattgaa
    26281 tgattttctg ggcgctgcaa cagaagatga tgtttgtccg gaggcactgt atcgttttga
    26341 aaagatggtg gaagaggcgg cacgcaacgc tgaagccgcc tctcagagcg cagcggcagc
    26401 aaagaaatca gaaacagcag cggcatcgtc caggaacgcg gcgaaaacat cagagacgaa
    26461 tgcaggtaac agcgcgaaag cggcagcttc ttcaaaaaca gccgcacaaa acgcagcaac
    26521 agcggcagaa cgttcagaga caaatgcccg tgcgtcagaa gaagcctccg cagacagtga
    26581 agaggcttcc cgccgtaatg cagagtcagc cgctgaaaat gccggagtcg ccaccacaaa
    26641 agcgcgggag gccgcagcag acgcaacaaa ggccgggcag aaaaaggatg aggctctgtc
    26701 ggcagcgaca cgagctgaaa aggcggcaga ccgcgcagaa gccgcagcgg aagtgactgc
    26761 agagccctgt gcgaatatag tgccgccgct gcctgatgtg tggataccgt ttaacgattc
    26821 actggatatg attacgggtt tttcgccatc ttataaaaag atagttattg gtgacgatga
    26881 aataacaatg ccaggcgaca agattgttaa gtttaaacgt gcttcaacag caacgtatat
    26941 taataagtcc ggccaactca agcttgctga agttgacgaa ccgcgatttg agcgcgatgg
    27001 cttattgatt gaaggacaga ggacaaatta tctgaggaac tcaaataaac cagactcatg
    27061 gactgttcat tccgcactga ataaaacatt tggcactgat aaacaggggt tcaattatgc
    27121 cacggtgaca cccacggaaa gtatagtggg aacaacaggt ggctatactg tgcatggtgt
    27181 ggttgcagca gacagattcc cgctggcaag tggtgaatgt ttcacttttt cgtgccgggt
    27241 taaaggcgct aaagcacgat gcaggttaag agtttcagtt attattggtg gaacagatac
    27301 cttctctgct gactcttatc ttgatctgga tacccggatc gcaacagtaa gcggtaatac
    27361 atcccttata acagccaaag ctgaacaaca gggcgagtgg acctactatg aggccactta
    27421 tacagctaat acggacattg ataccgttaa ctgtgctttt tatatgacaa ataaaataag
    27481 taatgagaca ttctatgatg actcaacatt aaccatgacg acgccgcaaa ttgaactggg
    27541 caatacggca tcgtcattta ttgtaactac aatgccaaca acacgcgcaa gtgatgtagt
    27601 tactatccca tcgcagaata acctgtcaac acggcctttt acggtattgt gcgaagtaag
    27661 caggaactgg agtacaccgc ccaatgttgc gccaaggata tttgatgttg gagggcacag
    27721 tattgatgat aattatttat cgctggggtt tgttgcaaca ggaaagataa gcgccaacgt
    27781 aggaatggtt cagccacaaa ttgcctcaga tggagaaagg ttcattgtgg gtgtgagagc
    27841 taaatctgat ttatcagtaa atgcaatatg caatggtaat tatacaacaa accttaatgg
    27901 taaaatattt ggagttacag caacatcgta ccggtttggt gggcagaccg cagcaggaac
    27961 gcgtcatttg tttggacaca tcagaaattt cagagtctgg tttaaagaat taaatgacag
    28021 gcaaatcaag gaggcagtat gaaagattta actttgaaat ttcctggtaa cagagagttt
    28081 aaatccttcc tgtcatctct tgactgggag gaggatgaag acctccagaa taaactgtta
    28141 gtcgatgaaa ttggtttcac ctacacagaa acaggggtaa cagaagaggg agaacctgtc
    28201 tgtgtccgga atgacggtta ttttgtcaac attcgcattc ttgatgactt gtttgatgtt
    28261 tctgtattct ctgattatgt cgtggagctg gaaacaccgc ttcgggaatg gagctgaaag
    28321 gaggaaataa tggatataag ccccttactt catgcacttt gtgctgtggc tgcgcagata
    28381 ctggttggtc tttttaccgg aaactgggct tacggagcga tagccggttg tacgttcttc
    28441 attgcgcgtg aacataccca ggcagaatat cgctggattg aaatgttcgg gcatggcaag
    28501 cgaatgaata tgccgtggtg gggcggtttt gatccgcgag cttgggatgt ggcaagcctg
    28561 atggattttg ctgtgccggt ggtggcgtgt ctgctggtct ggctgttggt taatcgtggg
    28621 tgaaaaaagg tgagctgtat atgcaacgga ggaagaaacc ccgttgctgg aagccaggaa
    28681 aaagtatcgg gtgttgctgt cctcggatgt tgtgctaatt gggtgataac agatcctgtg
    28741 tatgggagtt tccctttttg cgtgcgttga tgctggtaac ggcaaacgtc atgatgaaca
    28801 aaaccgcgaa taagacgaca atcgtcggag ctggtgcgct gtcgataaaa aaggacaacc
    28861 agacaccagt cattgacact attaccgata tgccagtcgc cagtaggagc gcaatatgaa
    28921 agcgttgtgt caggagtacc gcaatggcgc caggcgcaat gagcagagaa atggagagaa
    28981 tgatacctac cgctttcagc gtcgccacaa tggtcagaga gaccatgcac agcagcccat
    29041 aatgcagcca tctcgtatgc aaaccgctta cctgcgcctg ttgataatca aagctgaaca
    29101 gcaaaaaatc ccgccatttt acgctaataa caagtgtaac cagcccggca ataatcatcg
    29161 tctggattat atcgccgatg gttatcccga gcatgtcgcc gaaaagaata tggtcaagat
    29221 gtacgtctgg tttgactgca atatacaaga tcagacctgc ggcaaacatg ccagaaaaaa
    29281 caatccccat cactgtatct tgcttgattc ggctgttgtc tttcaggtat cccgtcgcca
    29341 ccgcacagaa tactccggcg acgaatgccc ctgtagccaa aggtaacccc agaatccagg
    29401 caagcacgat gccaggaaaa accgcatgac tcatcgcgtc acccatcagt gcccaacctt
    29461 tcaggaccag aaagaccgac agcagcgcac agggtatgga aactaccagt gaaatcagca
    29521 gtgcgtgact cataaaggtg aactgcagtg gctccagtaa taatgccatc atgagcgatc
    29581 ctccagcgcc ttatgcgcac gccgacgatt tgccaaaagc ccatgggtgg gcgcaaagac
    29641 aaatgctaaa agaaacagca gtgtctgcgc caccacgatg attccacctg tcgcgccgtc
    29701 cagaaagtaa ctgacccacg cgccgaggaa actggttaca ctgccaatag ttacagcaat
    29761 catgagcagg cggggaaaac gatcggttaa caaccatgct gttgcaccgg gagtcaccac
    29821 cagacagatc accagaaagg caccaaccgt ttgcagcgcc gcaacggtcg aaaccgacag
    29881 cagggtgaag aagaggagtt ttaatctgcc cggatgcaat ccaatagcac gggcgtgatt
    29941 ctcgtcgaaa aaggtcacca taagatcttt ccatttgaaa aaaagcacga tgatcgagag
    30001 aatgccaatg atagtgagtt gcaggatatc cgccggatcg attgccagaa tattgcccag
    30061 gacgatggtc tgaatgttca cagatgtcgg gttcaatgac accataaaca gccccaggcc
    30121 aaaaaaggac gagaagatca gaccgatgat ggcatcttct tttaagcggg tgcgttggtt
    30181 aagaaacagc atgctgcccg cagccagtcc gccggaaaag aaggctccca gagaaaacgg
    30241 aagccccagc atatatgccc ccgcaacacc cgggacaata gagtgcgaca acgcatcgcc
    30301 aatcagcgac cagcctttta gcatcagata gcatgacagg aaagcgcaga gaccgccgac
    30361 catcgccgag acccacatcg cattgagcat atattcatag ctgaagggtt ccagtagcac
    30421 gttcatcttt cttccctctg caccgctgac ggtcgatgag ccacaaaagg gcgttcatcg
    30481 tcagtaataa tgctttcttc cgagccgtta agtgtgacat ggcgcagtac gccgctaaaa
    30541 gccagctcta ggttctcggc tgtaaaagtg gtgtctgtcg gcccgcttgc caggacggtg
    30601 cctttgacca tgaccgtata atcgcaaaat gtcgtgacgg atccgagatt gtgtgttgag
    30661 acaagcatcg ttttgccttc cgcgcgtaac tccctcaaca ggctgatgat tttggcttcg
    30721 gttttcacat caacgccagt aaaaggttca tccagcagga tcacatcacc ctgctgtgca
    30781 atcgctctcg ccagaaagac gcgtttcttt tgtccaccgg aaagctcgcc gatttgtcga
    30841 tggcgaaaat tcaccatatc gacacgttcc agcgcatcgg tgacaatttg acgatccctc
    30901 tttttggcga tacgcaacat acccatatgc ccatagcggc ccatcatcac cacatcttcc
    30961 accagtacag gaaatgacca gtcaacatct tctgactgag ggacgtaggc aaccaggttt
    31021 ttctgtaacg cctgtcgcgt gggaataccc agaacagata tctttccgct ggtcagacgc
    31081 acaaatccca taatcgcttt aaacaacgtc gattttccgg aaccgtttac cccaaccaga
    31141 gcggcaatag atccacttgg tactgtgaag gatgcatcgc gcagtgctgt gtgcccgtta
    31201 cgccaggtga cagtaacatc attaacgaca atgcctgcag attgcatcat tatttctccc
    31261 ttttcccagc tttaattccc tgtaccagcg tactggtagt aaccttaaga aggtcgatat
    31321 acgtcggtac cgggccgttt tctgtgctca gggaatcgac atagagcaca ccgccgtagt
    31381 gtgcgccggt ttcacgcgca acctgacgcg ctggtttatc ggaaatcgta ctctcgctaa
    31441 agactgccgg gatatgattt ttcttaacta tatcaacaac cttacgtacc tgctgcggtg
    31501 ttccttgttg atcggcatta atcggccaca gataaagctc ttttagcccc aaatcgcgtg
    31561 cgagataaga aaaagcccct tcactggtga ccatccatcg ctgattctca gggagttccg
    31621 taatctgctt acgcaggggg gcaagggttt gggtaatctt ggctttataa gtatcggcat
    31681 tgcgttggta ggtttgtgca tttgccggat cgtattttat caacgcatca cgaatattat
    31741 cgacgtaaat cagagcatta tctggcgaca tccatgcatg ggggttaggt ttgccctcat
    31801 agggtccttc ggtgatccct acaggcgtca cacccgaaga gacaattact tctggaaccc
    31861 cattgagatg ctggtaaaag cgttggaacc acaattccag attcatacca ttggcgagaa
    31921 tcagttgtgc cccctgcgca cgtttaatat cgccaggggt aggctgatac tcatgaattt
    31981 ctgcaccagg cttggttatg gatgagactt ctgcagcatc tcccgccacg tttttggcca
    32041 tatccgcgat gatggtaaat gttgtaatga ccttgaattt ttcagttgca cttgcctgaa
    32101 atgcgatcga gcaggtgagt gcgagccccc ccaagagcat ggttactttt tttatcgagt
    32161 gcataattta gtacctatag tgagcaaaat tagaacaaat atagcaacgg ctatgtttta
    32221 tagcacagcc tatacaaaat gaaaatgatt atcattagca gctttgaggc ccaaaacagg
    32281 gattaggttg tttcctgctg gcgacgcgtt attgaggaaa aaagtaaggc agctagtagg
    32341 ctttgaaata acgttttgcg gttggctgat gcaatttcga gagtgcatgt attgaatgat
    32401 ttctagccgt tactgatttt cgtatttttt gtatgggagg atttgcacct ccccccaccg
    32461 agcctccatg actttactcc actgtctcta gggctgctgt gtgccaggag cggaagcagg
    32521 ggggccagag actccttaaa agttgatagc tcgttttgca gggagactta cacggtaagc
    32581 gttattccga agagcttaaa attgaagcag tcaaacgggt tgttgagcgt gtttatgcgc
    32641 tgccatctga ttaatcgacg gaagcagttc cgtttggtct atgatgcagt tgtccggcag
    32701 gcgctctgtg acgcaaaaga acgataggag tagcattgaa gtgaacgagg ttatgcttgt
    32761 cttatattat cctctatttt aaaaacatca gctggttgtg taagagtttt tattgtttta
    32821 tcttgttgac tttgctttta tgaaaacaga gtgattgata caatgaaaac cttaagtggg
    32881 aaagagttta ggaaattatt taatcgttat gagacaggat tctatctaag tgagtttgaa
    32941 tacttaaagg actttgatcc tttgtttcct gaatgcgtag ggaaagaatt aaagttgggt
    33001 tataaacgaa aagttgatgt atggtgcgaa gaggatgctg cgctatatgc agaatttata
    33061 gctacaaaag aaaggctgaa aagaggccgg ttaatcctaa aaataaacca agtgtggtcg
    33121 cgtgtatatc ctgcttatat ttatgcaatt gaagaaagaa taaatgtcag ggcaaagggg
    33181 agagagtcat ttaagtatga aactgtgcaa gaaaaacaat gtaaactttc cataatgtta
    33241 gatggtctga aagaccttga atgtgaaata gctatgattt caagtgagtt tgaaattgaa
    33301 aaacactcta tgcactattt ttatatgatt tttgatattg aacgctatat aaatgactgc
    33361 agttactttg ttttttctgc tgctaaagtt gttaaaggcg tgattcaatg cattggttac
    33421 attgacaaaa ataacaaagc aagttgcgat gaattttatt caggcagcta tgaatgcttg
    33481 gatgatgatc aggaaacact gaactattta aatgaatcat gcgcagaggg tatagacgct
    33541 gataaagatc tcatcaggaa gaatgagtta ttagccttat ccctgaagga attgtatcaa
    33601 cttctcgttt caaaaaaata acaagtaata cggcgagcga tatgacgtgc catgggatat
    33661 ccgcacccag cagcatgttg tctccacgat gtccgcagtt cgctcataat agacattcac
    33721 tacagttata gtagaaggta tgcatgctgc tgagtgggga aagtgtgaaa gaaaagaaga
    33781 cagctgcttt gtttgtcgtc acgtttatct tcattggcta tgcaagtcgt aatacaaggc
    33841 gggacaaaac tgagacacat aaggcctcgc aatggcttgc aaggccacac atgtattgag
    33901 atgttaataa aatgtagact tgtaattttg atataaatg
//
LOCUS       DAFGPF010000049        33364 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFGPF010000049 DAFGPF010000000
VERSION     DAFGPF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33364
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.049"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(279..1679)
                     /gene="asnS"
                     /locus_tag="LSX49_002566"
     CDS             complement(279..1679)
                     /gene="asnS"
                     /locus_tag="LSX49_002566"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBL7168965.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPNTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
     gene            complement(1848..3050)
                     /gene="pncB"
                     /locus_tag="LSX49_002567"
     CDS             complement(1848..3050)
                     /gene="pncB"
                     /locus_tag="LSX49_002567"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBL7168966.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLENKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPLEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            3316..5928
                     /gene="pepN"
                     /locus_tag="LSX49_002568"
     CDS             3316..5928
                     /gene="pepN"
                     /locus_tag="LSX49_002568"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HBL7168967.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDVPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIVNEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     QDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            complement(5971..6738)
                     /gene="ssuB"
                     /locus_tag="LSX49_002569"
     CDS             complement(5971..6738)
                     /gene="ssuB"
                     /locus_tag="LSX49_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HBL7168968.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQDDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMQRGEFETRLRKQG"
     gene            complement(6735..7526)
                     /gene="ssuC"
                     /locus_tag="LSX49_002570"
     CDS             complement(6735..7526)
                     /gene="ssuC"
                     /locus_tag="LSX49_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HBL7168969.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVMAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRELVEMARS
                     YGLSGMPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            complement(7538..8683)
                     /gene="ssuD"
                     /locus_tag="LSX49_002571"
     CDS             complement(7538..8683)
                     /gene="ssuD"
                     /locus_tag="LSX49_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HBL7168970.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLLGETVDFNGKHIHVRGA
                     KLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPKLVKEKIEHVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQASFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVANDFIPRNVAQS"
     gene            complement(8680..9639)
                     /gene="ssuA"
                     /locus_tag="LSX49_002572"
     CDS             complement(8680..9639)
                     /gene="ssuA"
                     /locus_tag="LSX49_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415456.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein SsuA"
                     /protein_id="HBL7168971.1"
                     /translation="MRKIIKLVLAGLLSVSTIAVAAESSPEALRIGYQKGSIGMVLAK
                     SHQLLEKRYPQTKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLTTFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     LSAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            complement(9632..10207)
                     /gene="ssuE"
                     /locus_tag="LSX49_002573"
     CDS             complement(9632..10207)
                     /gene="ssuE"
                     /locus_tag="LSX49_002573"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HBL7168972.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFVP
                     EDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSTLKAQEILHGVFADDSQVIDYQHKPQFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNAHA"
     gene            10444..11454
                     /gene="pyrD"
                     /locus_tag="LSX49_002574"
     CDS             10444..11454
                     /gene="pyrD"
                     /locus_tag="LSX49_002574"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HBL7168973.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
                     KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQVMHHKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            11628..12170
                     /gene="zapC"
                     /locus_tag="LSX49_002575"
     CDS             11628..12170
                     /gene="zapC"
                     /locus_tag="LSX49_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415466.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HBL7168974.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     SPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWMPMPGDAAYVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(12167..13276)
                     /gene="ycbX"
                     /locus_tag="LSX49_002576"
     CDS             complement(12167..13276)
                     /gene="ycbX"
                     /locus_tag="LSX49_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HBL7168975.1"
                     /translation="MATLTRLFIHPVKSMRGIGLTHTLADVSGLAFDRIFMITEPDGT
                     FITARQFPLMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRALQQ
                     RCPASVKMEQFRPNLVVSGASAWEEDSWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPADEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAGA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSATGDDGTILCCSCVPKTALKLAR"
     gene            13374..15482
                     /gene="rlmKL"
                     /locus_tag="LSX49_002577"
     CDS             13374..15482
                     /gene="rlmKL"
                     /locus_tag="LSX49_002577"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HBL7168976.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETANIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYANRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            15494..17401
                     /locus_tag="LSX49_002578"
     CDS             15494..17401
                     /locus_tag="LSX49_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7168977.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVDGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKSEEAAAPKAETVKRSSSKLSYKL
                     QRELELLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            17531..18784
                     /gene="pqiA"
                     /locus_tag="LSX49_002579"
     CDS             17531..18784
                     /gene="pqiA"
                     /locus_tag="LSX49_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HBL7168978.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            18789..20429
                     /gene="pqiB"
                     /locus_tag="LSX49_002580"
     CDS             18789..20429
                     /gene="pqiB"
                     /locus_tag="LSX49_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HBL7168979.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     LLDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTSNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            20426..20989
                     /gene="pqiC"
                     /locus_tag="LSX49_002581"
     CDS             20426..20989
                     /gene="pqiC"
                     /locus_tag="LSX49_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309063.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HBL7168980.1"
                     /translation="MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQVAVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLARVWSQEAASIAQEIKRLP"
     gene            21245..21412
                     /gene="rmf"
                     /locus_tag="LSX49_002582"
     CDS             21245..21412
                     /gene="rmf"
                     /locus_tag="LSX49_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HBL7168981.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(21482..22000)
                     /gene="fabA"
                     /locus_tag="LSX49_002583"
     CDS             complement(21482..22000)
                     /gene="fabA"
                     /locus_tag="LSX49_002583"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HBL7168982.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAND
                     LKVGLFQDTSAF"
     gene            complement(22069..23829)
                     /locus_tag="LSX49_002584"
     CDS             complement(22069..23829)
                     /locus_tag="LSX49_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HBL7168983.1"
                     /translation="MTITKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIADAARTLQSDAGQLVGGHYEVSGHTIRLR
                     HAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVSQWCRWVTFTARHNHLPAPGADAWPVLIREAA
                     RYTGEQETLPLSPQWILRQCQEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            24015..24467
                     /gene="matP"
                     /locus_tag="LSX49_002585"
     CDS             24015..24467
                     /gene="matP"
                     /locus_tag="LSX49_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HBL7168984.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDEL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE"
     gene            complement(24543..25595)
                     /gene="ompA"
                     /locus_tag="LSX49_002586"
     CDS             complement(24543..25595)
                     /gene="ompA"
                     /locus_tag="LSX49_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706879.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HBL7168985.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     IPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTA
                     KLGYPITDDLDIYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEI
                     ATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKH
                     FTLKSDVLFTFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQA
                     LSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRV
                     EIEVKGIKDVVTQPQA"
     gene            complement(25951..26460)
                     /gene="sulA"
                     /locus_tag="LSX49_002587"
     CDS             complement(25951..26460)
                     /gene="sulA"
                     /locus_tag="LSX49_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HBL7168986.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTAEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            26679..27308
                     /gene="sxy"
                     /locus_tag="LSX49_002588"
     CDS             26679..27308
                     /gene="sxy"
                     /locus_tag="LSX49_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HBL7168987.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     CLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(27271..29433)
                     /gene="yccS"
                     /locus_tag="LSX49_002589"
     CDS             complement(27271..29433)
                     /gene="yccS"
                     /locus_tag="LSX49_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HBL7168988.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGQLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVTQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWKFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNQALAGLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(29443..29889)
                     /locus_tag="LSX49_002590"
     CDS             complement(29443..29889)
                     /locus_tag="LSX49_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBL7168989.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            30012..32066
                     /gene="helD"
                     /locus_tag="LSX49_002591"
     CDS             30012..32066
                     /gene="helD"
                     /locus_tag="LSX49_002591"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HBL7168990.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWRRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGMQQQIRQALSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIEGARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGDRCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDEGQLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(32098..32556)
                     /gene="mgsA"
                     /locus_tag="LSX49_002592"
     CDS             complement(32098..32556)
                     /gene="mgsA"
                     /locus_tag="LSX49_002592"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBL7168991.1"
                     /translation="MELTTRTLPSRKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(32652..33314)
                     /locus_tag="LSX49_002593"
     CDS             complement(32652..33314)
                     /locus_tag="LSX49_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HBL7168992.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
BASE COUNT         8448 a         8281 c         8758 g         7877 t
ORIGIN      
        1 tgtttctgat ggaaacttta tcgaccgggc acaaaatctt ctttcagaca tccagaatgc
       61 caaaaaatcg tataaaaatt gtgctatcag ctaagaaaaa actaatccgc aataagaatg
      121 cagattattt tttgtgcgta aatgttgcag tgtaatattc cgtaacagga tgatcgttat
      181 ggcagggttg caaatagatt gcttgactta acaaacagat aacttgacag aaaggataaa
      241 aaaagagcca gcgggcgctg gctcttgaag acactaaatt agaagctggc gttacgcgga
      301 gtacgtggga acggaataac atcacgtacg ttttgcacgc cagttacgta agcaatcagg
      361 cgttcaaaac caagaccgaa acctgaatgc ggaacagtac cgtagcgacg cagatcgcga
      421 taccaccagt aatcttcttt gttcaggccc atttcaagca tacgctcgtc cagcacgtcc
      481 agacgttctt cacgctggga gccaccaatg atctcaccga tgcccggagc cagaacgtcc
      541 atagccgcaa cggttttacc gtcttcgtta aggcgcatat agaacgcttt aatatctttc
      601 ggatagtttt taaccactac tggtgcttta aagtgttctt ccgccagata acgctcatgc
      661 tcagaagaga gatcgacgcc ccagtaaacc gggttttcaa acttcctgcc gcagttttcg
      721 agaatggtca ctgcgtcggt gtaatccacc tgcgcgaaat cggcctcaat gaagcgttcc
      781 agacgtgaaa cggcatcttt atctacgcgt tcagcgaaga atttcatgtc gtcagcgcgt
      841 tcttcgagaa ccgctttgaa gacatatttc agcatggctt cagccagacc tgcgatatcg
      901 ttcaggttag caaacgccac ttccggctcc agcatccaga attccgccag gtgacggctg
      961 gtgttggagt tttcagcacg gaaagtcggg ccgaaggtat aaattttgga caatgcgcaa
     1021 gcgtaggttt cgccgttcaa ctggccagat acggtcagga aagactcttt accaaagaag
     1081 tctttgtcga aatccacttt gccctgatcg ttacgcggca ggttttccag atccagcgta
     1141 gaaacacgga acatttcgcc tgcaccttcg gtatcagatg cggtaatcag tggcgttgaa
     1201 acccagaaga atccctgctc gttaaagaag cgatgcagcg cctgcgccag cgtatggcga
     1261 acgcgcgcga cggcaccaat caggtttgtg cgcggacgca ggtgagcgac ttcacgcaga
     1321 tactcaatgc tgtggcgttt tgccgccatc gggtaagtgt ttggatcttc aacccaacca
     1381 gcaacttcaa ccttgctggc ctgaatttca aattgttgcc cctggcccgg cgacgccacg
     1441 actttacccg ttacaatgac cgagcagccg gtggtcagac gcaggacgtc ttcattgtaa
     1501 ttgggcagag aattattgat gacagcctgt acaggatcaa agcaggaacc gtcataaacg
     1561 gcgaggaagg agatgccagc ttttgaatct cggcgggtac gtacccatcc gcgcacggtg
     1621 acttcgctgt caacggctac gcggccctgg agtacgtcgg ctacaggcac aacgctcata
     1681 atattctctc tgttaatagt cggaaaaaat aaacacttgt ccacccgtaa atggggggat
     1741 acctatgtta cctggcatct gcaatcagac aagcagaatt cgcaaatgca gcgaaagatt
     1801 tcggaattaa aggtaaaaaa agggagccga ttagctccct gatgatatta actggctttt
     1861 ttaatatgcg gaaggtcgaa cgctttgcgc agcgcccgaa caaacgcttt atcgtggcag
     1921 atcgttttgc cagggctgtc agaaagtttc gccaccggtt taccgttaca ctctaccaac
     1981 ttaatgacaa tattcagagg ttttacctgg gggatatcgc aggtcaggcg agtcccaata
     2041 ccaaaactta attgcacgcg ggaagagaag tggcggtata gctcaaccgc tttgcgtaaa
     2101 tccagattgt cagagaaaac cagcgtttta ctctgtggat caattcccag cttttcataa
     2161 tgtgcaatgg ctttttcacc ccattcaagc gggtcgccag agtcatggcg caggccctgg
     2221 taacgactgg caaattccac gccgaaatct cgcaggaaag catccatggt gatgcagtcg
     2281 gttaacgcaa tgccaagttg gtcgggatac tcttccagcc aggcagcaag tgcagctcgc
     2341 tggctgttgg ctagatccgg gctgatttgc tgatgcgcct ggaaccattc gtgtgcctgt
     2401 gttcccattg gcgtgaggga aagccgacgc gccagatcgt agttgctggt gcccacgaac
     2461 caggattcct gttgcagacg tttcacgatg gtttcttgta cttcgcgaga aaaacggcgg
     2521 cgggtgccaa aatccatcag atggaagcgc gacatatcaa gaccggcggt taatgccgag
     2581 aagtcgacta atttgttttc cagcgtgtcg agggcttgcg caacgtcggc ctgcggtgag
     2641 cgatagcgat gtaccatttc actgataacc gccagcaaag gaacttccca gaggatgact
     2701 tcacgccacg ggccgcttaa acgaatatcc agcttgccat tatcgttgga cacggtgact
     2761 tgttccgggt taaagcggaa ctcgcgtagc cagttaagat agtcggcctt aaagaaaggc
     2821 agggcagaga gccactgata ttcatcatcc tgcaggcgca ggtgctgcat cgcctgaacc
     2881 tgttcacgaa tagcatcggc ataaataccc agcagatcgt cacctcggca acgaaactcc
     2941 gccgcgacat gcacatcgta atagtgatga aacacggctt gctgcatatg caacttataa
     3001 gcatctgtat ccagcaacga gtgcagaaca ggagaagcga attgtgtcat aggtgcgcag
     3061 tagcgtcctc gtacaggagc gtttagtaca ataaacatct tcaggaactg ctggagtata
     3121 ccttgtttcg caatttattg aaccccgatc acaccatatg ccacctttct ggtcgatggc
     3181 ataacgcggt gtatgttata aaaatgtagc aataaaggcg tttgtacctg aaaagatgaa
     3241 gattctgcat agcgcgattt acgcaacagg aatagactga acaccagact ctataaaaga
     3301 tgctaaaggt tatttatgac tcaacagcca caagccaaat accgtcacga ttatcgtgcg
     3361 ccggattacc agattactga tattgacttg acctttgacc tggacgcgca aaagacggtc
     3421 gttaccgcgg tcagccaggc tgtccgtcat ggtgcatcag atgttccgct tcgtctcaac
     3481 ggcgaagacc tcaaactggt ttctgttcat attaatgatg agccgtggac cgcctggaaa
     3541 gaagaagagg gcgcactggt catcagtaat ttgccggagc gttttacgct taagatcgtt
     3601 aatgaaatta gcccggcggc gaatactgcg ctggaagggc tttatcagtc aggcgatgcg
     3661 ctttgcaccc agtgtgaagc cgaaggtttc cgccatatta cgtattatct cgaccgcccg
     3721 gacgtgctgg cgcgttttac caccaaaatt attgccgata aaaccaaata tcccttcctg
     3781 ctttccaacg gtaaccgcgt tgcgcaaggt gaactggaaa atggacgtca ttgggtacag
     3841 tggcaggatc cattcccgaa accgtgttac ctgtttgcgc tggtggctgg tgattttgat
     3901 gtactgcgcg ataccttcac tacccgctct ggtcgtgaag tggcgctgga gttgtatgtc
     3961 gatcgtggca accttgatcg tgcgccgtgg gcaatgacct cgctgaaaaa ctccatgaaa
     4021 tgggatgaag aacgcttcgg cctggagtat gacctcgaca tctatatgat cgtcgcggtg
     4081 gatttcttca atatgggcgc aatggagaat aaggggctga atatctttaa ctccaaatat
     4141 gtgctggccc gcaccgacac cgccaccgac aaagattacc tcgatattga acgcgttatc
     4201 ggccatgaat atttccataa ctggaccggc aaccgtgtca cctgccgcga ctggttccag
     4261 ctcagtctga aagaaggttt aaccgtcttc cgcgatcagg aattcagctc tgaccttggt
     4321 tcccgcgcgg taaaccgtat caataatgtg cgcaccatgc gcggattgca gtttgcagaa
     4381 gacgccagcc cgatggcgca cccaattcgc ccggatatgg tcattgaaat gaacaacttc
     4441 tacaccctga ccgtttacga gaagggcgcg gaagtgattc gtatgatcca cactctgctt
     4501 ggcgaagaaa atttccagaa agggatgcag ctctatttcg agcgtcatga tggtagcgca
     4561 gcgacctgtg acgattttgt gcaggcgatg gaagatgcgt cgaatgtcga tctctcccat
     4621 ttccgccgtt ggtacagcca gtccggcacg ccggttgtga ccgtcaaaga cgactacaat
     4681 ccggaaactg agcagtacac cctgaccatc agccagcgca cgccagctac gccggatcag
     4741 gcagaaaaac aaccgctgca tattccgttt gccatcgaac tgtatgacaa cgaaggcaaa
     4801 gtgatcccgt tgcagaaagg cggtcatccg gtgaattccg tgctgaacgt cacccaggcg
     4861 gaacagacct ttgtttttga taatgtctac ttccagccgg tgcctgcgct gctgtgcgaa
     4921 ttctctgcgc cagtgaaact ggaatataag tggagcgatc agcaactgac cttcctgatg
     4981 cgtcatgcgc gtaatgattt ctctcgctgg gacgcggcgc aaagtttgct ggcaacctac
     5041 atcaagctga acgtcgcccg tcatcagcaa gggcagccgt tgtctctgcc ggtgcatgtg
     5101 gctgacgctt tccgcgcggt gctgctcgat gagaagattg atccggcgct ggcggcagaa
     5161 atcctgacgc tgccttccgt caatgaaatg gcagaactgt tcgatatcat cgatccgatt
     5221 gctattgccg aagtacgcga agcactcact cgtactctgg cgactgaact ggcagatgag
     5281 ctgctggcta tttacaacgc gaattaccag agcgagtacc gtgttgagca tgaagatatt
     5341 gcaaaacgca ctctgcgtaa tgcctgcctg cgcttcctcg cttttggtga aacgcatctg
     5401 gctgatgtgc tggtgagcaa acagttccac gaagcgaaca atatgaccga tgcgctggcg
     5461 gcgctttctg cggcggttgc tgcacaactg ccatgccgtg acgcgctgat gcaggagtac
     5521 gacgacaagt ggcatcagga tggtctggtg atggataaat ggtttatcct gcaagccacc
     5581 agcccggcgg cgaatgtgct ggagacggta cgtggtctgt tgcagcatcg ctcatttacc
     5641 atgagcaacc cgaaccgcat tcgttcattg attggcgcat ttgcgggcag caacccggca
     5701 gcgttccatg ccgaagatgg cagcggttat cagttcctgg tggaaatgct taccgacctg
     5761 aacagccgaa atccacaagt ggcttcgcgc ctgattgaac cgttgattcg cctgaaacgt
     5821 tacgatgcca aacgtcagga gaaaatgcgc gcggcgctgg aacagttgaa agggctggaa
     5881 aatctctctg gcgatctgta cgagaagatc accaaagcac tggcttgata aataaccgaa
     5941 tggcggcaat agcgccgcca ttcggagaat ttacccctgt tttctcaggc gagtttcaaa
     6001 ttcaccacgc tgcatcaccc gctgcaatac ttccgcttcc agctctgcta atcgtaccga
     6061 ccctaaccgg cgcggacggg ggatatccac cgtcaaatcc agaccaattt ttccctcttc
     6121 aattaacaac acccggtcag ccatcgctac cgcttcgctc acatcatgcg tcaccagcaa
     6181 gacggtaaag ccgtgctcct gccagagtga tacaatcaaa tcctgcatct cgagtcgcgt
     6241 taaagcgtcc agcgcaccga gtggttcatc aagcaacaat aaacctggtc gatgaatcag
     6301 cgcccttgcc agcgccacac gttgtttctg cccgccagaa agtgcggcag gccattcccc
     6361 cgcgcgattc tccagtccta ccgcagccag agcccgacgc gcggcatcgc gccactggcc
     6421 tttaaggcct aacccaacgt tatcaatcac cgatttccac ggcagcagac gcgcgtcctg
     6481 aaacatcatt cgcgtatcat cctgaatctc agccagcggt gtggtgcccg ctaacacgtc
     6541 gcctgcggtt ggcgtttcca gacctgccag caggcgcagc agggtacttt tgccaccacc
     6601 gctgcggccc accaccgcca caaactgacc tgctggaata tgtaaatcca gttggttcag
     6661 gacgatattt tccgcgtaat gtttgcttac tgcattgagc aacaatggtg tgccctggtt
     6721 cagacgagca gtattcatac cgtggcctcc ttcaaatgat aagccgggtt ccagcgcaac
     6781 cagagacgct ctaacagctg cgcgctgacg tcagcaagtt tgccgagcag ggcgtaaaga
     6841 ataatggcga ctaccaccac gtccgtttgc agaaactccc gcgcattcat cgccagataa
     6901 ccaatgccgg aattggcaga aatagtttcg gcaacgatca gcgtcagcca catcaggccc
     6961 aaagcaaaac gcacaccgac cataattgag ggcagggcac caggcaggat cacatggata
     7021 aacagcggca tgccggataa tccatagcta cgtgccatct ccaccagctc acggtcgata
     7081 ttacggatgc catgccaggt gttgatataa atggggaata gcgtaccgag cgccaccaga
     7141 aagatttttg cggattcatc aatgccaaac cacaaaatca ccagcgggat cagcgccaga
     7201 tgcggcacgt tgcgcaacat ctgaattgag gtatccagca gtcgctcacc ccagcgtgac
     7261 agcccgctaa tcagccccag aattaatccc agcgatccgc caattgaaaa accaatcagt
     7321 gcacgccagg agctgatcgc cagatgctgc cacagttcgc cgctggcaga gagcgtccag
     7381 aacgccatca ccactccttc cggtgagggc aaaatacgcg tcgatagcca gccaaccgag
     7441 gaggccagtt gccacaccgc cacgatgccc accggtaaaa accagggggc aacgcgcaat
     7501 aaccacttct tcactggcgt tgccatcatc gtgttcctta gctttgcgcg acgttacggg
     7561 ggataaaatc attcgccacc gcttcgcctt gtggattcag cggttgtggc tggggaattt
     7621 ccgggatggc gacatccaga tgtgggaaca gtaactcgcc gacccgatac gcttcttcca
     7681 gatgcgggta gcccgaaagc acaaaactgt cgatgccaag tgcagcgtat tcgttgattc
     7741 gcgcggcgac cgtaggacca tcgcccacca gcgctgtccc ggcaccgccg cgcactaagc
     7801 caacacccgc ccataaattg gggctgatct ccagattgtc gcgcttgccg ttatgtagcg
     7861 ccgccattcg ctgttgtcct acggaatccg ttcgggcgaa tgaggcctgt gctttggcga
     7921 tagtttcatc atcaagatgc gagattaacc gctcggcggc ctgccacgct tcgtcgttgg
     7981 tttcacgaac aatcacatgc agacgaatac cgaaacgaat tttgcgtcca tgcgcggcag
     8041 ctttcgcccg cacgtgttcg attttctctt ttaccagttt cggtggttcg ccccaggtaa
     8101 ggtagagatc aacttgttct gccgccagct cctgggcgac atctgacgat ccgccaaagt
     8161 aaagcggagg ataaggctgt tgaatcggcg ggaagagcag tttggccccg cgtacatgaa
     8221 tatgtttgcc gttgaaatcc acagtctcgc caagcaacaa ccgccgccag acctgggtaa
     8281 attctgccga ggcttcgtaa cgctcgctat gatcaaggaa cacgccgtcg cctgccagtt
     8341 cttggggatc gctgcctgtg accaggttaa acaacgcacg tccgttagag agacggtcaa
     8401 gcgtggcggc ctggcgggcg gcaacggtag gtgaggttac gctggggcgc agggcgacaa
     8461 gaaacttcag ccgttgtgtc accgggatca tcgacgccgc caccagccac gcatcttcac
     8521 acgatcgccc cgtcgggatc agcacaccgg tatagcccag acgatccgcc gcttgcgcaa
     8581 tttgttgcag ataaccgtga tcaaccggac gtgaaccttc ttccgttccc agataatgcc
     8641 cgtcaccgtg ggtcggtaaa aaccagaaca tattcagact cataattgtt ttccttccag
     8701 ttgagtgggc tgccagatgc gctggcgaat atcgactttt ttcggcacca gacggttttc
     8761 ataaaacaga tctgccgttt gctgctgtaa ggcggcaact tcagcgctca acggtttgat
     8821 ggtggtggga ggacgatgat ccagatacga ggcaataacc ggtgccggta agcccatcgt
     8881 ttttgccagt aaagcgatgc tttgttcgcg ctggctgcgg gttaacgcat cggcctcact
     8941 aaaggttgtc agcacaccct gaataaaagc gccgtttttt tctgcatacg gacgagctgc
     9001 cagataaaac gatccagttt gattgagatc ggtgccgtct ttcagcaccc gcacgccgcc
     9061 ctgtaataat gcagcggagt agtagggatc ccagatagcc caggcgtcaa cgttaccttg
     9121 ctggaacgcg gcgcgggcat cggcaggcgt caggtaagtg ggctgaatat ccgtgaattt
     9181 aagcccggcc tggcgaaggg ctcgcagtaa aagattgtgc gaactggaac ctttctgaaa
     9241 ggcaactttg tgacctttaa gatcggctac ggttttgatc gggctgtttt ctgccaccag
     9301 aatcacttcg gctttgggct tcggtggctc gacgcccacg tataccaaat cagccccggc
     9361 agcctgggca aagattggcg gaatatcccc ggtactgccg agatcgatac tgccaacgtt
     9421 taacgcctcc agcatctgtg ggccagcggg gaactcgacc caggagattt ttgtttgcgg
     9481 atagcgtttt tccagtaact ggtggctttt tgccagcacc ataccaatac tgcctttttg
     9541 atagcctata cgtaacgctt caggcgagga ttctgcagca accgcaatcg tagagacgct
     9601 aagtaaaccc gccagcacca gtttaatgat cttacgcatg ggcattacct cgcaaagaca
     9661 gtaggtcagg aacctgaaca tcgcggcggt gcaacgcctg ccagaaagtt tctagcgcgg
     9721 tatcaagacg agtttgcaga tttggcgtga actggggttt gtgttggtaa tcaattactt
     9781 gcgagtcatc ggcaaacacg ccgtgcagga tctcctgggc tttcagcgta cttaaaactg
     9841 gcttaagggc ataatcgacc gccagcagat gggccacggt gccgcctgtc gccagcggca
     9901 gcaccacttt gccttgcaac gcacgttctg gcagcaggtc gagcagggtt ttcagtgcac
     9961 cggaataggc ggctttatac acaggcgtgg cgacaatcag cccatcggcc tgttgcagct
    10021 gttcggtgaa ggtcttgagt gccggactat cgaaacgagc ataaagcaga tcttccggga
    10081 cgaagttttg caaattccag tgataaacct ctacatccag gccatttagt ttttcccgcg
    10141 catattccag caaggagctg gagcgagaag gaaatcgagg actacccgcc agggtgatga
    10201 cacgcatact ctctccttat aaccaattgt tcttgttttg ttaacattga taacaattcg
    10261 gtcagtctga cagagggcgt ccgcgagtcg aaatgattta tctgaggaag aaaagccaaa
    10321 aaaagcataa aaaaagcgca ataagaaaac gtttgctatt tattgccgca ggtcaattcc
    10381 cttttggtcc gaactcgcac ataatacgcc cccggtttgc acaccgggaa tccaggagag
    10441 ttcatgtact accccttcgt tcgtaaagcc cttttccagc tcgatccaga gcgcgctcat
    10501 gagtttactt ttcagcaatt acgccgtatt acaggaacgc cgtttgaagc actggtgcgg
    10561 cagaaagtgc ctgcgaaacc tgttaactgc atgggcctga cgtttaaaaa tccgcttggt
    10621 ctggcagccg gtcttgataa agacggggag tgcattgacg cgttaggcgc gatgggattt
    10681 ggatccatcg agatcggtac cgtcacgcca cgtccccagc caggtaatga caagccgcgt
    10741 ctctttcgtc tggtagatgc cgaaggtttg atcaaccgta tgggctttaa taatcttggc
    10801 gttgataacc tcgtagagaa cgtaaaaaaa gcccattatg acggcgttct gggtattaac
    10861 atcggcaaaa ataaagatac gccggtggag cagggtaaag atgactatct gatttgtatg
    10921 gaaaaaatct atgcctatgc gggatatatc gccatcaata tttcatcgcc aaatacccca
    10981 ggattacgca cactgcaata tggtgaagcg ctggatgatc tcttaactgc gattaaaaat
    11041 aaacaaaatg atttgcaagt gatgcaccat aaatatgtgc cgatcgcagt gaagatcgcg
    11101 ccggatcttt ctgaagaaga attgatccag gttgccgata gtttagttcg ccataatatt
    11161 gatggcgtta ttgcaaccaa taccacactc gatcgttctc tggttcaggg aatgaaaaat
    11221 tgtgatcaaa ccggtggctt aagtggtcgt ccgcttcagt taaaaagcac cgaaattatt
    11281 cgccgcttgt cacaggaatt aaacggacgc ttgccgatta ttggtgttgg cggcattgac
    11341 tcggttatcg ctgcgcgtga aaagattgct gcgggtgcct cactggtgca aatttattct
    11401 ggttttattt ttaaaggtcc gccgctgatt aaagaaatcg ttacccatat ctaattattt
    11461 cttcaaattc ctctttataa gataatcagg gctttatttt cagccctggt tgttttatat
    11521 tcatcgctgt tgcttattta gacattttgt acttttattg ttgaggttat taagcgaagc
    11581 gacaatggat tgtgtcgctg cggttttata aggttgggga gtggcagatg cgaattaaac
    11641 cagacgataa ctggcgttgg tattacgatg aagagcacga tcgaatgatg ctcgatttag
    11701 ccaatggtat gctatttcgc tcacgttttg cgcgcaaaat gttgactcca gatgcctttt
    11761 ctcccgcagg tttttgcgtt gatgacgccg cgctctattt ctcttttgaa gaaaagtgcc
    11821 gcgattttaa tttatctaaa gaacaaaaag ccgaactggt gctgaatgca ctggtagcaa
    11881 ttcgttatct caaaccgcaa atgccgaaaa gctggcattt tgtatctcat ggtgaaatgt
    11941 ggatgcccat gccgggcgat gcggcctacg tttggttgag cgacactcac gagcaagtga
    12001 atttactggt cgttgaatct ggcgagaatg ccgcgctatg tctactggca caaccctgcg
    12061 ttgttattgc gggtcgcgcg atgcagttgg gcgacgccat taaaatcatg aacgacaggc
    12121 tgaaaccgca ggttaatgtt gacagcttca gcctcgaaca ggcagtctaa cgcgccagct
    12181 taagcgcagt cttcggtaca caactacagc aaagaatagt gccatcatcg cctgttgctg
    12241 atttttttag cggcgtgact tcgccttcta aaagctgaac acggcaactt ccacaaatgc
    12301 ctgcgcggca agaataaggg atacgaattc cctgattttc taattgctcc agcagcacct
    12361 gttggttatt tccacgaaat gcctgtccct gccagtcaat atctacgttt gcgtccggtt
    12421 gttgcgtgat gttggcagta tcatcagcgg cacctgcgcc gtaaatttta gctggagccg
    12481 ttgccagaat ttccacctca tcgccaacgc gaatcacgcc gctattacgg gcaattaaat
    12541 tctgaccaaa atcgacatcg ccgttatcct gggcagtacg gaaagattgc agcgttttta
    12601 atggttcgtc tgccggatgt ttttgccctt tttctgggct gacggtggtg aaaatacagc
    12661 ggctacaagg cttaaccaca tcaaacacga catcaccaat gcgaatcact ttccagctat
    12721 cttcttccca ggccgatgca ccggaaacca ccagattggg gcggaattgc tccattttta
    12781 cactggccgg acaacgttgt tggagagcac gtaacgaggc ctcgttagca agaaggtaag
    12841 gatagccatc agcaaatgac aggggtacag tgttgtggcg tttcacgcgc cgggtcattt
    12901 gtggccccac ccagcgtaat tgcacttcgc gggagaaaaa tccacttagc catttgttga
    12961 tcgcatctgg cgcaattcgc gcggtaaaat gtgtgcccca aacttcggtt ggtgcgtctt
    13021 gtgtggcgaa atcagcaaaa cgaacatatg cgctactgcc atctggtgcg gtgagatgca
    13081 agccatcatg cacgggtgaa ggagtaaacc gtaccattag cggaaactgg cgagcggtaa
    13141 taaacgtacc gtcaggttcc gtgatcataa agatgcgatc gaaggccaga ccactgacat
    13201 ctgccagggt atgtgtaaga ccaatgccgc gcatcgattt aacaggatga ataaaaagcc
    13261 gggttaatgt cgccacggtg cggtcctcaa atgaaaataa gccctcaact ttatgacatg
    13321 acgcgcttat tagctataat gcgcaacaat tttcttagag taaaagtgac gatatgaatt
    13381 ctctgtttgc cagtacggcc cgtgggctgg aagagctgtt aaaaactgaa ctggaaaacc
    13441 tgggggccgt tgaatgccag gtggttcagg gtggggtcca tttcaagggc gacacacggc
    13501 ttgtttacca gagcctgatg tggagccgcc tggcctcgcg tattatgttg ccgctgggcg
    13561 agtgtaaggt ttacagtgat ttagacctct atctcggcgt tcaggcgatc aactggacag
    13621 agatgtttaa tcctggcgcg accttcgctg tccatttcag tggtttaaat gacaccattc
    13681 gcaacagcca gtacggcgcg atgaaagtga aagacgcgat cgtcgatgct ttcacgcgga
    13741 aaaatctgcc acgtcccaat gttgatcgcg atgcgccgga tattcgcgtt aacgtctggc
    13801 tgcataaaga aaccgccaat atcgcccttg atctcagtgg tgatggcttg catctgcgtg
    13861 gctatcgtga tcgtgctggt attgcaccga tcaaagaaac cctggcagcc gcgattgtga
    13921 tgcgatccgg ctggcagcca ggaacaccac tgctcgatcc aatgtgtggt tctggtacgt
    13981 tgctgattga agcagcgatg ctggcgaccg accgcgcacc gggcttgcac cgtggccgtt
    14041 ggggctttag cggctgggcg cagcatgatg aagctatctg gcaggaagtg aaagcggaag
    14101 cgcaaactcg cgcccgtaaa ggcctggcag agtatagctc tcatttttac ggttcggaca
    14161 gcgacgcccg ggtgattcaa cgtgcgcgca ctaacgcccg tcttgcgggg attggtgaac
    14221 tgatcacctt tgaggtgaaa gatgtcgcgc aactgaccaa tccgctgccg aaagggccgt
    14281 acggtacagt gttgagcaac ccgccatacg gtgaacgtct ggacagcgaa ccggcgctga
    14341 ttgcgctgca tagtctgctg ggccgaatca tgaaaaacca gttcggtggc tggaatctct
    14401 ctttgtttag tgcctcgccg gatctgctaa gctgcctgca gctgcgtgca gacaaacagt
    14461 acaaggcgaa aaacggcccg ctggactgcg tacagaaaaa ctaccacgtt gccgaaagca
    14521 caccagacag caaaccggca atggtagcgg aagactacgc caaccgcctg cgtaagaacc
    14581 tcaaaaaatt cgagaagtgg gcacgtcagg aagggattga atgttatcgc ctgtatgatg
    14641 ccgatctgcc ggaatataac gttgccgttg accgttatgc cgactgggtg gtggtgcagg
    14701 agtatgcgcc gccaaaaact attgatgcgc acaaagcgcg tcagcgtctg ttcgatatta
    14761 tcgctgcaac catttcggta ctggggattg cgccaaacaa actggtgctg aaaacccgtg
    14821 aacgccagaa gggcaaaaat cagtaccaga aactgggcga gaagggcgag tttcttgaag
    14881 ttaccgaata taacgctcac ttgtgggtga acttgacgga ttacctcgat accggtctgt
    14941 tcctcgatca ccgtatcgcc cgtcgtatgc tcggtcagat gagcaaaggc aaagatttcc
    15001 tcaacctgtt ctcctatacc ggtagcgcca ccgtgcatgc gggattaggc ggcgcgcgca
    15061 gcaccaccac cgtggatatg tcgcgtactt atctggagtg ggcagaacgc aacctgcgtc
    15121 tgaatggcct aaccgggcgt gcgcatcgcc tgattcaggc cgattgcctg gcgtggctgc
    15181 gtgaggcaaa tgaacagttc gatctgatct ttatcgatcc gccaaccttc tctaactcaa
    15241 aacgaatgga agatgcgttt gatgttcagc gcgatcatct ggcgctgatg aaagatttga
    15301 aacgtctgct gcgtgcaggt gggacgatca tgttctcgaa caacaaacgc ggcttccgta
    15361 tggatctcga cggcctggcg aaactgggac tgaaagcaca agaaattacg caaaaaacgc
    15421 tctcccagga tttcgcccgt aaccgccaga tccacaactg ctggctgatt accgcagcct
    15481 gaaaggaata gtaatgtcat taatcagtat gcatggcgca tggctgtcgt tcagcgacgc
    15541 gccgcttctc gataacgcag aactgcatat cgaagataac gaacgtgttt gtctggtggg
    15601 tcgtaacggc gcaggcaaat cgacgttaat gaagatcctc aaccgtgaac aggggctgga
    15661 tgacggtcgc attatttacg agcaagattt gattgtagct cgtctgcaac aggatccgcc
    15721 gcgtaacgtt gagggtagcg tttatgattt cgttgccgaa ggcattgaag aacaagcgga
    15781 atacctgaaa cgctatcacg atatttcgcg cctggtgatg aacgacccga gcgagaaaaa
    15841 tctcaacgaa ctggcgaagg ttcaggaaca gctggatcac cacaacctgt ggcagctgga
    15901 aaaccgcatc aacgaagtgc tggcgcaact gggattagat cctaatgttg cgctgtcgtc
    15961 gctttccggt ggctggttgc gtaaagcggc attaggacgc gcgctggtga gcaatccgcg
    16021 cgtattgctg ctcgacgaac cgactaacca cctggatatt gaaaccatcg actggctgga
    16081 agggttcctc aaaaccttca atgggacaat tattttcatt tcccacgacc gttcgtttat
    16141 ccgcaatatg gcgacgcgca ttgttgatct cgatcgcggc aagctggtga cctatccagg
    16201 gaattacgac cagtacctgc tggaaaaaga agaagccctg cgcgtggaag aattacaaaa
    16261 tgccgagttc gatcgcaaac tggcgcagga agaggtgtgg atccgccagg ggatcaaagc
    16321 acgtcgtacc cgtaatgaag gccgcgtacg cgccctgaaa gcaatgcgtc gtgagcgtgg
    16381 tgaacgtcgc gaagtgatgg gtaccgcaaa gatgcaggtg gaagaagcca gccgctccgg
    16441 taagatcgtt ttcgaaatgg aggacgtttg ctaccaggtt gacggtaagc aactggtgaa
    16501 agatttttct gcccaggttc tacgcggcga caaaattgcc ctgattggtc cgaatgggtg
    16561 cggcaaaacc acgctgctga aactaatgct cggtcagctt caagcagaca gcgggcgtat
    16621 tcacgttggc accaaactgg aagtggctta tttcgatcag caccgcgcgg aactggatcc
    16681 cgataaaacg gtgatggata accttgccga aggtaagcaa gaggtgatgg ttaacggcaa
    16741 gccacgccac gtattgggct atttgcagga cttcctgttc catccaaaac gggcgatgac
    16801 gccggtacgt gcgctttctg gcggtgagcg taaccgcttg ttgttggcgc gtttgttcct
    16861 caaaccaagc aacttattga ttcttgacga accgaccaac gatcttgatg tcgaaacgct
    16921 ggaactgctg gaagaactga tcgacagcta tcagggcacg gtattgctgg ttagccacga
    16981 tcgtcagttt gtcgataaca ccgttacaga atgctggatc ttcgaaggcg gcggtaaaat
    17041 tggtcgttat gtcggcggtt atcatgatgc ccgtggtcag caagaacagt atgtggcgct
    17101 caaacagcct gcggtgaaaa aaagcgaaga agccgccgcg ccaaaagcag aaactgtaaa
    17161 acgcagcagt agcaaactaa gctataaatt gcagcgtgaa ctggagctgc taccgcaatt
    17221 gcttgaagat ctggaggcga agctggaagc tttacagacg caagtggcgg atgcttcctt
    17281 cttcagtcag ccgcatgagc agacgcaaaa agtactcgct gatatggctg ctgcagagca
    17341 ggagctggag caagcctttg aacgctggga gtatcttgaa gcgttaaaaa atggtggctg
    17401 atcgcaaaat agtcgattta aacagagact gctgacaacg gtaaaattgc ctgatgtact
    17461 gggtttatca ggcatgaaaa ccaacacttt gttagtcatc tgcaaaatag cgcatcatta
    17521 aggagtacca atgtgcgaac atcatcatgc cgcgaagcac atcctgtgct cgcagtgtga
    17581 catgctggtg gcgttaccgc gccttgagca tggtcagaaa gcggcatgtc cccggtgtgg
    17641 cacaacgtta accgtggcgt gggatgcccc tcggcagcgt cccaccgcct atgcgttggc
    17701 tgcactgttc atgctgttgc tgtccaactt gtttcctttt gtgaatatga acgttgcagg
    17761 agttaccagt gaaattacat tactggaaat tcccggcgtg cttttttctg aggactacgc
    17821 cagcctcggc acctttttcc tgttgtttgt gcaactggtt cccgcgtttt gtctgataac
    17881 cattctgtta ctggtgaatc gcgcggaatt accggtccgt ttaaaagagc aactggcacg
    17941 ggtgcttttt caactcaaaa cctggggaat ggcggagatt ttcctcgcgg gtgtgctggt
    18001 cagtttcgtt aaactgatgg cttacggcag cattggggta ggcagcagct ttctcccctg
    18061 gtgtttattt tgtgtcctgc aactgcgcgc ttttcagtgc gttgatcgtc gctggttatg
    18121 ggacgacatc gccccgatgc cagaactgcg ccagccgcta aaaccaggcg tcacggggat
    18181 acgccagggg ctgcgttcgt gttcctgttg tacggcaatc cttcctgctg atgaacccgt
    18241 gtgcccgcgt tgtagtacca aagggtacgt tcggcgtaga aacagcctgc aatggacact
    18301 cgcgctgctt gtaacgtcta tcatgctgta tcttccggct aatattttgc ccatcatggt
    18361 gacggattta ttaggctcga agatgccgtc gacgattctc gctggggtca ttctgttatg
    18421 gagcgaaggc tcttatcccg tcgctgcggt gatttttctg gccagtatta tggtgccaac
    18481 gttaaagatg atcgccattg cgtggctgtg ttgggatgcc aaaggacacg gcaagcgcga
    18541 cagtgaaaga atgcatttga tttatgaagt tgttgagttt gtaggccgct ggtcgatgat
    18601 tgacgttttc gttatcgcgg tgctctcggc gctggtgcgt atgggaggtt taatgagtat
    18661 ttatccggca atgggtgcat taatgtttgc tttagtcgtc ataatgacaa tgttttctgc
    18721 tatgacgttt gacccgcgtt tgtcgtggga tcgtcaacct gaatcagagc atgaggagtc
    18781 ctgacagtat ggaatctaat aatggggaag ccaaaatcca gaaagtgaag aactggtctc
    18841 ccgtgtggat atttcctatc gtcacggcgc tcattggggc ctgggttctt ttttatcatt
    18901 acagccatca gggaccggaa gtgaccctga tcaccgcgaa tgcggaagga attgaaggtg
    18961 gcaaaaccac cattaaaagc cgtagcgttg acgtcggcgt ggttgaaagc gccacactgg
    19021 ctgatgattt gacgcacgtt gaaatcaaag cgcggctgaa ttccggtatg gaaaaattgc
    19081 tgcataaaga taccgtcttt tgggtggtga aaccgcagat tggtcgagaa gggattagcg
    19141 gcctgggaac gctgctgtct ggggtttata tcgaactgca gccaggcgcg aaaggcagca
    19201 aaatggataa atacgatttg ctggactcgc caccgttggc cccgcctgat gcgaaaggta
    19261 tccgtgtgct tctcgatagc aaaaaagccg ggcagctctc gccaggggat ccggtgctgt
    19321 tccgtggcta tcgggtaggt tcggttgaaa ccagcacttt cgatacgcaa aaacgcaata
    19381 tcagctatca actgttcatc aatgcacctt atgaccgact ggtgaccagc aatgttcgtt
    19441 tctggaaaga tagtggcatt gcggttgatc tgacgtcagc gggaatgcgt gtggagatgg
    19501 gctcattgac aacgctgctt agtggcggtg tcagctttga tgtgccggaa ggtctggatt
    19561 tagggcagcc agtggcaccg aaaacagctt tcgttttgta tgatgatcag aagagcattc
    19621 aggattcgtt gtacaccgat cacattgatt atctgatgtt ctttaaagat tcggtacgcg
    19681 gtctgcaacc gggagctccg gtagaattcc ggggtattcg cctgggtacc gtaagcaaag
    19741 tgccattctt tgcgccgaat atgcgtcaga catttaacga tgattaccgt attccggtac
    19801 tgattcgtat cgagccagag cggctgaaaa tgcagcttgg cgaaaatgcg gatgttgttg
    19861 agcaccttgg cgaattgttg aaacgtggtt tacgcggatc gctgaaaacc ggaaacctgg
    19921 tcactggcgc actgtatgtt gatctcgatt tctatccaaa tacgcctgca ataaccggta
    19981 ttcgtgaatt taatggttat cagattatcc cgaccgtcag cggcggcctg gcgcaaatcc
    20041 agcaacgact gatggaagcg ttggataaga tcaacaaact gccactgaat ccgatgattg
    20101 aacaggcaac cagtacgctt tctgaaagtc agcgcacaat gaaaaacctg caaacgacgc
    20161 tggatagcat gaacaagatc ctcgccagcc agtcgatgca gcagttaccg acggatatgc
    20221 agtcaacgtt gcgtgaattg aatcgcagta tgcagggctt ccagcctggt tccgcagcct
    20281 acaacaagat ggtggcggat atgcagcgcc ttgatcaggt gttgcgagaa ctgcaaccgg
    20341 tgctgaaaac gctcaacgag aagagtaacg cgctggtatt tgaagcgaag gacaaaaaag
    20401 atccagagcc gaagagggcg aaacaatgaa aaagtggcta gtgacgattg cggcactgtg
    20461 gctggccgga tgcagctccg gtgaaattaa taaaaactat taccagttac ctgtggtgca
    20521 gagcggtaca caaagcaccg ccagccaggg taatcgcctg ttatgggttg agcaggtcgc
    20581 tgttcctgac tatctggcgg ggaatggtgt ggtttatcaa accagtgatg tgaagtatgt
    20641 gattgccaac aacaacttgt gggccagccc gttggatcaa cagttgcgca acaccctggt
    20701 tgccaacctg agtacgcaac tgcccggctg ggtggttgcc tcccagcctc tgggaagcgc
    20761 ccaggacacg ctcaatgtta ccgtcacgga gtttaacggt cgctatgatg gcaaggtcat
    20821 tgtcagtggt gagtggctgt tgaaccacca gggacaactg atcaaacgtc cgttccgtct
    20881 ggaaggagtg caaactcagg atggttacga tgagatggtt aaagtgctgg cccgtgtctg
    20941 gagtcaggaa gccgcttcta ttgcgcaaga gataaagcgt ctaccttaat cataaagatt
    21001 tgtaaatata accgtctccg gtatgttgcc tgaggcggtt tttttgtttc taacgtgcgg
    21061 aaaaagttgt tcctcttcac attttttgta caaccgacat gcccgtgtag ctcacaaata
    21121 tgacagtggc gtgaattttg cgcattgacg gcagttatga ttcgcggtat tgcttaactg
    21181 tggttgcata tttagtaatc actgttttct tttccaccag aaaccagtat gagggaaacg
    21241 aggcatgaag agacaaaaac gagatcgcct ggaacgggca catcaacgtg gttatcaggc
    21301 cggcatcgcc ggacgctcaa aagaaatgtg tccctatcag acgctgaatc aaaggtcaca
    21361 atggctggga ggctggcgag aagccatggc ggacagggta gtaatggcct gattctgtct
    21421 ctttaaaaag aaacctccgc attgcggagg tttcgccttt ttatactctg tctgattatt
    21481 atcagaaggc agacgtatcc tggaacagac cgactttcag gtcgttggcg gtatagatca
    21541 aacgaccatc aaccagcact tcgccatcag ccaggcccat aatcagacga cggttaacta
    21601 tgcgtttaaa gtgaatacga taggtcactt ttttcgccgt cggcagcacc tgacctgtga
    21661 atttcacttc acctacgccc aacgcgcgac ctttaccttc gccgcccagc cagccgaggt
    21721 agaaccctac cagctgccac attgcgtcca ggcccaggca tcccggcata accggatcac
    21781 caatgaagtg gcatccgaag aaccacagat ccggattgat atccagctct gcttcaacat
    21841 accctttgtc gaagttacca cccgtttcgg tcattttgac cacacggtcc atcatcagca
    21901 tgtttggtgc tggcaattgc gggcctttag cgccaaacag ttcaccgcga ccagaggcaa
    21961 gaaggtcttc ttttgtatag gattcgcgtt tatctaccat gttctctgta agccttattt
    22021 tattgaagca cgcaggatag ctaacacgtg tacgctgaac aagtccgatc agttcggaat
    22081 aaaccagttc agccaacgta atggccatgg aaaacggtga cgtccttcct gttgcgatgc
    22141 ttgtgcgata cgttcctgga tggtttgcat cagcgtcgtc tggccttcgc catcccacac
    22201 cagatttaat aataacggca gtgcgtcagt cacatcgtct actgcccaga tggtgaattt
    22261 gccttcttct accgctttca ccagttcact gtgaagactt aaatggcgaa cgttagcagt
    22321 ggggataatg acaccttgtt tccccgttaa ctcacgttgc tggcaaatag caaagaagcc
    22381 ttcgattttc tcatttaaac caccgactgg ctgggcgcga ccgaactgat cgactgaacc
    22441 tgtgatagcg atactctgat tcaccggcac atcggcgagg gcgctgatca gagcgcagag
    22501 ttcagccatc gaggcactat cgccatccac ttcactgtat gactgctcaa atgtcagcga
    22561 tgctgagaag gggatctgtt gctcaagctg tagttccgac atcaggaacg cttgcatgat
    22621 catcatccct ttcgcatgga tattgccgcc aagctccgct ttgcgttcga tgtcggtgaa
    22681 ttcaccatcg ccaatatgca caacgcagct aatgcgagaa ggttcgccaa aagcgcgtgg
    22741 atgacccgga aattcaatga ccgaaagggc gttaatttgc ccgatgcgtt cgccttcggt
    22801 ttcaatcagg atttgctcct gaaggatctc atcctgcatg cgttcagcga ggaaaccttc
    22861 gcgccattca cgctgctgta gcattaagtt tagctgctcg ccggagaagg tgtcgccatc
    22921 acacagggag gcgacctctt gacactggcg gaggatccac tgcgggctaa gcggaagtgt
    22981 ttcttgttca ccagtgtagc gtgctgcttc gcggataagt accggccagg catccgctcc
    23041 cggtgctggt aagtgattat gtctggcggt aaatgtcacc cagcgacacc actggcttac
    23101 tgactccgca tcgacaatct gcagagtatc ttcaaattcg ctataaatag cctgctctga
    23161 aagctctggc tccatctcct ggaaatcagc caatgattcg cgttcgccta ccagaatgac
    23221 tttcagcttc aatggcatcg aaggcacaga gacggggaga gggcgcgact catcaaacgc
    23281 aacccagtca aaacgctcgc ggttaacgat atttttcagc cgcatccaca gcagaggttg
    23341 cgccagcagt gtacgcaaag agatgatgag aataccgcca tttgcctgat gcaccagacc
    23401 aggctgcagg gtaatatcgc cattaaactg acgcaggcag ccaaagagtt gctctgcttc
    23461 tacccagtcg gcagcgacaa cttgcgttaa agtcgcaaaa ttatcatctg cactcactgc
    23521 gtgacgtaag cggatggtgt ggccggaaac ctcatagtga ccgcccacca gttggcctgc
    23581 atcgctttgt agcgtacgcg cggcatcagc aataagattc agatactcag actcttccgg
    23641 ggccttcgcc agcataaaag aggaggatgc tcgcgtatgc agcaactgct ccagcgcaaa
    23701 ttgcagtcgc ggttgagtat cactgaataa aggatcgttt tcgtcaatca aatgtggctg
    23761 agcaaatatt tcctgatagc tatcggtatc aggaaccagg tcacgccatg caagtttcgt
    23821 aatggtcaaa gttgatgttt tttagtctgt tgtcaaagcc gcgattatac cgtaaccggc
    23881 actgcagcac acgtagaaag caacgacaat acgcctggca tgggcgttaa agctcacagg
    23941 atggagattc ttttcttcac tggcctaaaa agctgatatt ctgtaaagag ttacacggta
    24001 acattgagat cgctatgaaa tatcaacaac ttgaaaatct tgaaagcggt tggaaatgga
    24061 agtatctggt gaagaagcac cgcgaagggg agttaatcac ccgttacata gaagccagtg
    24121 ccgcccagga agccgtcgat gagttgctct cgctggaaaa tgaacccgtg ctggtaaatg
    24181 gttggattga caagcatatg aatccggaac tggtcaatcg catgaagcag accattcggg
    24241 ccagacggaa gcgccatttt aatgcggaac accagcatac gcgcaaaaaa tcgatcgatc
    24301 tggaatttat cgtctggcaa cgtctggctg gccttgcgca gcgtcgcggt aaaacgcttt
    24361 ctgaaacgat tgttcagctg attgaagatg cggaaaacaa agagaaatac gcgaataaaa
    24421 tgtcttcttt gaagcaggat ctgcaggcat tgctgggtaa ggaataactg tcaaaagtca
    24481 gttcaattta cgcaaggcga aaaaaaaccc cgcagcagcg gggtttttta ccagacgaga
    24541 acttaagcct gcggctgagt tacaacgtct ttgatgcctt taacttcgat ctctacgcga
    24601 cgatccggag ccaggcaatc gatcagtgca gcacgctgtt tcacgttgtc acaggtgttg
    24661 ccagtaaccg ggttggattc gcccatacca cgtgcggaga ttttgtctgc cgggatacct
    24721 ttagagatca ggtaatcaac aacggactga gcacgacgct cggacagagc ctggttataa
    24781 gcgtcagaac cgatgcggtc agtgtaaccc agaacaacta cggaaccgtc tttcggatcc
    24841 aggttgctca gctggctgta cagctgatcc agagcagcct gaccttccgg tttcagggtt
    24901 gctttgttga aggtgaacag aacgtcagac ttcagagtga agtgcttggt ctgtacttcc
    24961 ggtgccggag ctggagccgg agcaactact ggagctgctt cgccctgacc gaaacggtag
    25021 gaaacaccca ggctcagcat gccgttgtcc ggacgagtgc cgatggtgtg tgcatcaccg
    25081 atgttgttgg tccactggta ttccagacgg gtagcgattt cgggagtgat cgcatactca
    25141 acaccgccag cgaagaccgg agaaacgccg gtgtcgtggt ctttaaagga tgcgccacca
    25201 ggtacgttag ccttggtgtc tgcacgccat accataccac ccagacgagt gtagatgtcc
    25261 agatcgtcag tgattgggta acccagttta gcggtcagct gaacgccctg agctttgtat
    25321 gcgccgttga tgttgtcgcc tttgtacggc atacgaccta accagtcgta acccatttca
    25381 aagccaacat acgggttaac ctggtaacca ccaaaagcac ctgcacccag ttggttttcg
    25441 tgggtcggac cattgttagg aataaaacca gtgtcatggt actgggacca gcccagttta
    25501 gcaccagtgt accaggtgtt atctttcgga gcggcctgcg ctacggtagc gaaaccagcc
    25561 agtgccactg caatcgcgat agctgtcttt ttcatttttt gcgcctcgtt atcatccaaa
    25621 atacgccatg aatatctcca acgagataac acggttaaat ccttcaccgg ggatctgctc
    25681 aatattaact ctaccgatat cttcggctta tgccgagcac ccctggcgat gtaaagtcta
    25741 caacgtagtt gaaaacttac aagtgtgaac tccgtcaggc atatgaaaaa aaagtcttgt
    25801 ataaggtacg tttaatcttt tttgtcagcg acaatttaca gaagaaaatc gcggaaaccg
    25861 cttcagacaa gcctccgcaa ggaaaattag tcacgactga aagcattggc tgggcgataa
    25921 aaaaagttcc aggattaatc ctaaatttac ttaatgatac aaattagagt gaatttttag
    25981 cccggaaagt tgtctcgttg cgtgagagga tgcgcttacc ggacgcataa taaaccccat
    26041 agcgttacct tcatttgccg catcaacaag ttcagcatgc tcttctgcag tcaaatcatc
    26101 tgccaaccaa ccgatcacca cgctgtaatt gcccgtgcgt aaagcgcgaa ccattgactc
    26161 cacggtgtgg caaggggaga gctggctaat ctgcattact ttcgttaagg gtagcccaga
    26221 tgcctgaacc cattcgcgac tcagtttttg ttgcggtgtt aaccagagtt gccagcgtga
    26281 ttgctgaccg agttgctgta acaatggcaa cagtagaagt tgcgtcatca tgggctgatc
    26341 ttcgcgatag acaacttcac tgataagccc ggctgtagtg ttttccgtag agacacgcgc
    26401 aattttactt gctgcggatg agaacgacga agaacgatgt gcatagcctg aagtgtacat
    26461 aatcaatcca gcccctgtga gttactgtat gaatgtacag tacatccagt gacgacaaag
    26521 atcaacccta ttttcggaaa gagcctcgca aattttgtcg ttggtggcgg gaaaacataa
    26581 attaatcttg ccccttaaga ataagttgcc tattttcgta gttaacggat ccgttaatgt
    26641 gaatcattct tttatgttat gattttaaaa ggaattttat gaaaagcctc tcctataagc
    26701 ggatctataa atcacaagaa tacctggcaa cgttgggcac aattgaatac cgatcattgt
    26761 ttggtagtta cagcctgacc gttgacgaca cggtgtttgc gatggtttct gatggtgagt
    26821 tgtatcttcg ggcttgtgag caaagtgcac agtactgtgt aaaacatccg cctgtctggc
    26881 tgacatataa aaagtgtggc cgatccgtta ccctcaatta ctatcgagtt gatgaaagtc
    26941 tatggcgaaa tcaactgaag ctggtgcgtc tgtcgaaata ttctctcgat gcagcgctga
    27001 aagagaaaag cacgcgcaat acccgggaaa gactgaaaga tttgcccaat atgtcttttc
    27061 atctggaagc gattctcggg gaggtgggga ttaaggatgt acgggcgtta cgtatacttg
    27121 gggcaaaaat gtgttggttg cgactgcggc agcaaaactg tctggtgaca gaaaagattc
    27181 tgtttatgct tgaaggggcc attatcggca ttcatgaagc tgcgctccca gtggcacgcc
    27241 gccaggagct tgcagaatgg gctgactctc ttacgccgaa acaggagttt cctgcggaac
    27301 ttgagtaatc tggcgttgca gacgaccaat ctctggcagt aatgcaatca ataacccaac
    27361 ttgttgtacg accagaggtt ctttgctgtc tgcccgtggt tcaagttgct gcatccgctg
    27421 tttcaggcca gctaatgcct gattgacgcg ttcttcatca gcaggttgat gatgtagcgc
    27481 gtcatcaaca tagcaaacgg cgtcatcaag aaacgccaga atttcaggat tagttaactg
    27541 ctcccggtga gcaccgaggg ctgagatata gctggtaaac gtatggttaa ggcacagcaa
    27601 ccgaaacgcg gcttcgcgaa tttgcggggt aacgttcggt tcgctggaca tatttgatac
    27661 caccgacgcc agttcagcat cacggttgtg tgcatcgcgg cgggcaatac gatacgccag
    27721 acggttatca cgcccctgat ggtattgttc cagtatggca tcgagatacc ggcagttggc
    27781 ctctgtggcg cgttcgagca ttcgcggcag attgcgaaac ttccagtcag gccagatgta
    27841 gctcactgcc gcccacgcaa tggcacaacc aatcagcgta tcgattacgc gaggtaacgc
    27901 cacttcaaaa ccttcaccca gcaagttgaa acacagtagc accaaaagtg tgatgaacat
    27961 cgttgcatgg gcgtattgca cgttacggaa ggcaaaaaag agcacgccgg taataaccag
    28021 cagcaccagc tgcccttcca atgatggcac aaaccacagc acaggaatac caattgcgat
    28081 acctaccagc gtaccaataa tccttaactt caggcggtgg cgcgtggcgt tatagtttgg
    28141 ctggcagaca aacaaacttg tcagcaagat ccaatacccg tgatgcattc cggttatctg
    28201 aatgatggcg tagccgaagc acaacaccag cgacattctt accgcatgac ggaagagggc
    28261 ggattccggc gtgaagtgac ggctaagacg cagccagata tcactcaatc cgtgcgggct
    28321 gtcatcagcg agctcatttt cgtcattatt atggggcagt gcctgggcct gttctgattc
    28381 aattgttgcc agttgggcat caatggcacg taaattgttc agtaaaaatc ccagtgtttt
    28441 gagtaaatca gcaggcgcgc cgttatcgcg catccgctcc agcgcagcat caatatgcgt
    28501 aaaagcgcgc tcaaaatgcg gatcatgttg ataaggctga cgcagcaaaa tacagcgtga
    28561 cagttgctgg cacgcctggc cctgcatcga catcagccgc tgaaaacgga acagcacgtc
    28621 gctgtggcga aaatgttcac gcaatgtttg atattgaata tgagaagagc tggcacgctc
    28681 gtgaatatcc tgcgtgacaa agtaataatg cagtgtgcga cgcgttcccc gttgaccacg
    28741 atcgccacgt aagcgggtca gcagcgagag tttcgtctga ttcaatgtcg ccatcagctg
    28801 accgttggcg agagccaaat cgtacagcgg tgcctggctt tcatcttcaa tatcaggatc
    28861 aaacatgcgc gacttgagct caagataacg cgccagttgt tcatagcaac gcgccaggtt
    28921 gtcctgcagc gggcggaccg ggaacagcag atgaccaata agtgtcagga cgttgtacca
    28981 gacggcaccg gccagaagat acatcggctg ctgataccag tgctcataca gtgatgttcc
    29041 caacatagtg taaatggcga tcagcaatgc accgaaggca attgttgcat agcgttgacc
    29101 cagaccgccg agcaaaatga agccgctggt agagagcgtt aagccaatcg caaatagcca
    29161 gggccaggga aacagcaatt ctactgaggc cgaggcgata aaaaagcaga acagcgtaat
    29221 gatgaggtta cgcaaacgtc ccgccagtcg gtcatcgaga tcggtcagcg ccgctgccac
    29281 catcccaagc gtcagcggaa tcgtcagttt tacatcaccc agccaccacg gaaacgctgt
    29341 ggttccacaa agcgcaataa aaatacgcgc gtaatacagc caggcgctgt tccaggtata
    29401 gcgtttgagc aaaggactta gcataaaggc catattagtg gattattcaa aacgacgacg
    29461 tgcattggct tcgcgcgcag cttgcgctgt ttctaccgat accacgcgac gaccgaccgg
    29521 ccatagtgca atagcggcaa ttttaaagtt cgcaataccg acaggaatgc caatgatgga
    29581 aatacattgt gcgatgcccg ttgcaatgtg catcaggcat aaccaccagc caaagaaaat
    29641 cagccagaaa atattcaata ccgtaccgcc agtattcagc agcacatttt tgccagccgg
    29701 gttcagttca tcgacatgaa tagcttcatt gccataaggc accagagaca gtttagtgat
    29761 ctcccagcag gatcgtgtca gtggtaaggt aaaaatcagc acaatactga ccagagtcgc
    29821 caacagccag cccagagtgg tggcaaatcc gccaagcaca aagttcagaa tgttcaaaac
    29881 ggtacgcata aaacctcgct ttactgtggt tttcagtaat gggcggcaat tgtaacgttt
    29941 ttttgggctg gagcacgttt tctctgacgg ttacactgat aagaaataat ttcgtgtgga
    30001 tctacagagt catggaactg aaagcgacaa cgcttggaaa acgtctggca cagcaccctt
    30061 acgatcgggc ggtgatcctc aatgccggga ttaaagtctc cggcgatcgc cacgaatacc
    30121 ttattccttt caatcaatta ctggcgattc actgtaagcg cggtctggta tggggcgaac
    30181 tggagtttgt actgccggac gaaaaagtgg tgcgtctgca cggcaccgaa tggggcgaga
    30241 cgcagcgttt ttaccatcat cttgatgctc actggcggcg gtggagtggc gagatgagcg
    30301 aaattgcgtc tggcgtttta cgtcagcaac tggatttgat tgccacgcgc accggagaaa
    30361 ataaatggct gacgcgtgag caaacctctg gtatgcagca acaaatccgc caggctttgt
    30421 cggcgttacc attgccggtt aaccgactgg aagaattcga taactgccgt gaggcgtggc
    30481 gtaaatgtca ggcctggttg aaagacattg aaggcgctcg gttgcagcat aatcaggcgt
    30541 ataccgaagc catgcttacc gagtatgcgg attttttccg ccaggtcgag tcttcaccgc
    30601 tgaatccggc gcaggcccgg gcagtcgtta atggcgagca ttctttgtta gtgctggctg
    30661 gtgcaggaag cggaaaaacg tcggtgctgg tggcccgtgc aggctggttg ctggcgcgtg
    30721 gtgaagcgtc ccctgagcaa attttattgc tggcgtttgg tcgcaaagcc gctgaagaga
    30781 tggacgagcg tattcgagaa cgactacata ccgaagacat taccgcacgc acatttcatg
    30841 cgctggcgct gcatattatt cagcagggca gcaaaaaagt tccgatagtc agcaaactgg
    30901 aaaatgatac cgctgcccgt catgaacttt ttattgctga gtggcgcaag caatgcagcg
    30961 aaaagaaagc gcaggcgaag ggctggcggc aatggctgac ggaagaaatg cagtggtcag
    31021 tgccagaagg taatttctgg gatgatgaaa aattacagcg tcgtcttgcc tctcgcctcg
    31081 atcgctgggt aagtctgatg cggatgcacg gtggtgcaca ggcagaaatg attgccagtg
    31141 cacccgaaga gattcgcgat ctgttcagta aacgtatcaa gttgatggcc ccgttattaa
    31201 aagcctggaa aggtgcgctg aaggcagaaa acgctgtcga tttttcgggc cttattcacc
    31261 aggcgattgt gattctggag aaaggtcgct ttatcagccc gtggaagcat attctggttg
    31321 atgaatttca ggatatctcg ccgcagcgtg cagcgttgtt agcggcatta cgcaagcaaa
    31381 atagtcaaac gacgttgttc gctgttggtg atgactggca ggcgatttac cgattcagcg
    31441 gggcgcaaat gtcgctcacc acggctttcc atgaaaactt tggtgaaggt gatcgctgtg
    31501 atttagacac gacctaccgt tttaacagtc gtatcggtga ggtggcaaac aggtttattc
    31561 agcagaaccc aggccagctt aaaaagccgc taaacagctt aaccaatgga gacaaaaaag
    31621 ccgtcacatt attggatgag gggcaacttg acgctttgct ggataagctc tctggttatg
    31681 ccaaaccgga agagcgcatt ctgatcctgg cgcgttacca tcacatgagg cctgccagcc
    31741 tggaaaaagc ggcaacacgc tggccgaagt tgcaaatcga ctttatgacc attcatgcca
    31801 gcaaagggca acaggcggat tacgtcatca tcgttggctt gcaggagggg agtgatggtt
    31861 ttccggctgc ggcgcgggag tcgattatgg aagaggcgct actgccaccg gttgaggatt
    31921 tcccggacgc tgaagaacgg cggttaatgt acgtggcgct gacccgggca cgccatcggg
    31981 tatgggcact gtttaacaaa gagaatccct ctccttttgt cgaaatactg aaaaatctgg
    32041 atgtgccggt ggcgagaaaa ccgtaagaaa caggtggcgt ttgccacctg tgcaatatta
    32101 cttcagacgg tccgcgagat aacgctgata atcggggatc agaatatcga ccgcgtcgtt
    32161 aaaatgcggt gactggataa tgaagtctgc cgttgccacg ttggtggcga ccggaatgtt
    32221 ccataccgtt gccagacgca gcaaggcttt cacgtcagga tcgtgcggca cggcatttag
    32281 tgggtcccag aagaaaatca atacatcaat tttcccttct gagatcaatg cgccaacctg
    32341 ctggtcaccc cccattgggc cactcaacat cgcgttgacg ttcatgccgg tcgcgcggga
    32401 aattaagtta ccggtagtgc ctgttgcata cagtacgtgt tgttccagta acggttgatg
    32461 ccgttccacc cagctcatca gcatttgttt gcagtgatcg tgtgccacca gcgcaatatg
    32521 tttccgcgaa ggtaaagtgc gagtcgtcag ttccataatg tacatccgta gttaactttc
    32581 ctacagatta ctgtaagtac ttatcgctgc aagataaaga ctgaaaaagc ctgcgcacag
    32641 gcacaaaaat ctcaggagga tggttgtttt tccgcccatt gcaggaaagt atttcgcgtt
    32701 tgtgggtcag ccagtttaaa ccaatacttc agccgttgtt ctgtgagcac ctgagactgc
    32761 ggtggaatag catccagctc ggaaacaccc gaaagcagcg tactgtcatc tgccatcatc
    32821 gtggcaaatt gcggtagtga agcgcgtttc gcggatttgt tatagcgttc aacctcgacc
    32881 tcataatcaa tcgtttttgc cgttgaggta atggcgagaa tatccagctt taccggaatc
    32941 ggcgtcgcat cgccatccaa caattcaagg cgcggcgcgg catcaaaatg gttagcttcc
    33001 cgctcattct ccaggcgagg caggcgaaaa ttgacctggt tgatgagctg ggtattaaaa
    33061 ctaaccacca gtggagggga gatatagagc cgttcttcac tattggaaag atgaatcgtc
    33121 ttctcaacgc gaaacactaa ctgatgcggt ccattgtcca gttcaatgct gtccgcaccg
    33181 cgcagcagag agctggaaac cttcttaccg tcgagtacca gaagatcgac atcagtagaa
    33241 agccgcagcg tggtggcaaa aacggatacc ggcaaacata atgcaatcaa ggtggtcacg
    33301 atgccggttt tcatagatag ctcctgttaa aagaccgccc gaataataat gtgtcaaaat
    33361 tttt
//
LOCUS       DAFGPF010000050        33220 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFGPF010000050 DAFGPF010000000
VERSION     DAFGPF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33220
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.050"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            208..858
                     /gene="zinT"
                     /locus_tag="LSX49_002594"
     CDS             208..858
                     /gene="zinT"
                     /locus_tag="LSX49_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HBL7168993.1"
                     /translation="MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGV
                     FDDTNVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYRKGYA
                     TDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
                     YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH"
     gene            complement(1528..1617)
                     /locus_tag="LSX49_002595"
     tRNA            complement(1528..1617)
                     /locus_tag="LSX49_002595"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1581..1583),aa:Ser,seq:cga)
     gene            1711..2508
                     /gene="mtfA"
                     /locus_tag="LSX49_002596"
     CDS             1711..2508
                     /gene="mtfA"
                     /locus_tag="LSX49_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HBL7168994.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVALAE
                     RFLQQKRLVPLQGFELNSLRSCRIALLFCLPVLELGLEWLDGFHEILIYPAPFVVDDE
                     WEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFISLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH"
     gene            2609..2684
                     /locus_tag="LSX49_002597"
     tRNA            2609..2684
                     /locus_tag="LSX49_002597"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2642..2644,aa:Asn,seq:gtt)
     gene            2846..4108
                     /locus_tag="LSX49_002598"
     CDS             2846..4108
                     /locus_tag="LSX49_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL7168995.1"
                     /translation="MSLTSAKIRTLKPSDKPFKVSDSHGLYLRVKPGGSRHWYLKYRI
                     SGKESRIALGTYPAISLSDARQQREGIRKMLALNINPVQQRAAVRGSRTPEKVFKNVA
                     LAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
                     ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGA
                     YHQGRELTRHAVLLMLHVFIRSSELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRG
                     AKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMCENTVNKALRVMGYD
                     TKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAM
                     MQWWSDYLEACRESYAPPYTIGKNKFIP"
     gene            complement(4302..5606)
                     /gene="ybtS"
                     /locus_tag="LSX49_002599"
     CDS             complement(4302..5606)
                     /gene="ybtS"
                     /locus_tag="LSX49_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salicylate synthase
                     YbtS"
                     /protein_id="HBL7168996.1"
                     /translation="MKISEFLHLALPEEQWLPTISGVLRQFAEEECYVYERQPCWYLG
                     KGCQARLHINADGTQATFIDDAGEQKWAVDSIADCARRFMAHPQVKGRRVYGQVGFNF
                     AAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGCRRLCEWVKEAGTTTQ
                     NAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQA
                     NTPVRSFMFRQEGREALGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELL
                     HDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENK
                     DAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRS
                     VFQDSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV"
     gene            complement(5634..6914)
                     /gene="ybtX"
                     /locus_tag="LSX49_002600"
     CDS             complement(5634..6914)
                     /gene="ybtX"
                     /locus_tag="LSX49_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin-associated zinc MFS transporter
                     YbtX"
                     /protein_id="HBL7168997.1"
                     /translation="MSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALV
                     RAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAI
                     LTIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWG
                     NSVQVGGSYLGMMCGGGVFMMLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATI
                     PHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGN
                     IAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMMAPGHLLLQILQCLV
                     IVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGY
                     AACFLFAGAFTLLAAWVAYIRLHSARELMTSAID"
     gene            complement(6907..8709)
                     /gene="ybtQ"
                     /locus_tag="LSX49_002601"
     CDS             complement(6907..8709)
                     /gene="ybtQ"
                     /locus_tag="LSX49_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtQ"
                     /protein_id="HBL7168998.1"
                     /translation="MKDNNPADNLAWRVIWRQLISSVGSQARMLRRSMLALLLAAFMQ
                     GIAFACLYPIIDALLRGDAPQLLNWAMAFSVAAIVTLVLRWYGLGFEYRGHLAQATHE
                     LRLRLGEQLRRVPLEKLQRGRAGEMNALLLGSVDENLNYVIAIANILLLTIVTPLTAS
                     LATLWIDWRLGLVMLLIFPLLVPFYYWRRPAMRRQMQTLGEAHQRLSGDIVEFAQGMM
                     VLRTCGSDADKSRALLAHFNALENLQTRTHRQGAGATMLIASVVELGLQVVVLSGIVW
                     VVTGTLNLAFLIAAVAMIMRFAEPMAMFISYTSVVELIASALQRIEQFMAIAPLPVAE
                     QSEMPERYDIRFDNVSYRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTTVTKLLM
                     RYADPQQGQISIGGVDIRRLTPEQLNSLISVVFQDVWLFDDTLLANIRIARPQATRQE
                     VEEAARAAQCLEFISRLPQGWLTPMGEMGGQLSGGERQRISIARALLKNAPVVILDEP
                     TAALDIESELAVQKAIDNLVYNRTVIIIAHRLSTIAGAGNILVMEEGQVVEQGTHAQL
                     LSHHGRYQALWQAQMAARVWRDDGVSASGEWGHE"
     gene            complement(8696..10408)
                     /gene="ybtP"
                     /locus_tag="LSX49_002602"
     CDS             complement(8696..10408)
                     /gene="ybtP"
                     /locus_tag="LSX49_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtP"
                     /protein_id="HBL7168999.1"
                     /translation="MALAGLAALTSLGALLFLAWSLRDIRATPDAIPAWPLGGVIGCV
                     VLTFVLRLQAFNTSHYAAFHLENILRSRLARKALQLPPGVLQQMGSGSVAKVMLDDVK
                     SLHIFVADSTPLYARAIIMPLATIVILFWLDWRLAIATLGVLAFGSVVLVLARQRSED
                     MAQRYHKAREQVSAAVIEFVQAMPVVRTFDSGSTSFLRYQRALEEWVDVLKTWYRKAG
                     FSARFSFSILNPLPTLFVLIWSGYGLLHYGSFDFIAWVAVLLLGSGMAEAVMPMMMLN
                     NLVAQTRLSIQRIYQVLAMPELSLPQSDQQPQEASITFEQVSFHYPQARTGAALQEVS
                     FHVPAGQIVALVGPSGAGKSTVVRLLLRYADPDKGHIRIGGVDLRDMQTDTLMKQLSF
                     VFQDNFLFADTIANNIRLGAPDTPLEAVIAAARVAQAHDFISALPEGYNTRVGERGVF
                     LSGGQRQRITIARALLQDRPILVLDEATAFADPENEAALIKALAAAMRGRTVIMVAHR
                     LSMVTQADVILLFSDGQLREMGNHTQLLAQGGLYQRLWQHYQQAQHWVPGGTQEEVME
                     NERQ"
     gene            10665..11624
                     /gene="ybtA"
                     /locus_tag="LSX49_002603"
     CDS             10665..11624
                     /gene="ybtA"
                     /locus_tag="LSX49_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin transcriptional regulator YbtA"
                     /protein_id="HBL7169000.1"
                     /translation="MTESPQTQSEISIHQLVVGKPANDGNIPAQCELLRCSLQEGMDI
                     LLWRGHFARPETLQLHDDLGRINFSCILEGTSRFAIQGLRRHTDWELARNRHYITHTP
                     DCRGSASYCGRFESITLSFSPETLALWVPDISAVIKNKIDSHCCCQQHRCNAETHLTA
                     QALRHALMRMHSGFSHEQKPSTLWLQGQSLVMLSLVLDEHREDASCLSCHFTPMERQK
                     LLRAKDLLLADLTQAPGVAELARESGLSVLKIKRGFRVLFNNSVYGLFQAERMQEARR
                     RLANGNTSVMTVAADLGYANASHFSAAFQKQFGVTPSTFKRGM"
     gene            11815..17922
                     /gene="irp2"
                     /locus_tag="LSX49_002604"
     CDS             11815..17922
                     /gene="irp2"
                     /locus_tag="LSX49_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin non-ribosomal peptide synthetase
                     HMWP2"
                     /protein_id="HBL7169001.1"
                     /translation="MISGAPSQDSLLPDNRHAADYQQLRERLIQELNLTPQQLHEESN
                     LIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTLAAWNQLMLSRSPENAEEETPPD
                     ESSWPNMTESTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFEGHCLTASQLEQAIT
                     TLLQRHPMLHIAFRPDGQQVWLPQPYWNGVTVHDLRHNDAESRQAYLDALRQRLSHRL
                     LRVEIGETFDFQLTLLPDNRHRLHVNIDLLIMDASSFTLFFDELNALLAGESLPAIDT
                     RYDFRSYLLHQQKINQPLRDDARAYWLAKASTLPPAPVLPLACEPATLREVRNTRRRM
                     IVPATRWHAFSNRAGEYGVTPTMALATCFSAVLARWGGLTRLLLNITLFDRQPLHPAV
                     GAMLADFTNILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQRYP
                     HGAPVVFTSNLGRSLYSSRAESPLGEPEWGISQTPQVWIDHLAFEHHGEVWLQWDSND
                     ALFPPALVETLFDTYCQLINQLCDDESAWQKPFADMMPASQRAIRERVNATGAPIPEG
                     LLHEGIFRIALQQPQALAVTDMRYQWNYHELTDYARRCAGRLIECGVQPGDNVAITMS
                     KGAGQLVAVLAVLLAGAVYVPVSLDQPAARREKIYADASVRLVLICQHDASAGSDDIP
                     VLAWQQAIEAEPIANPVVRAPTQPAYIIYTSGSTGTPKGVVISHRGALNTCCDINTRY
                     QVGPHDRVLALSALHFDLSVYDIFGVLRAGGALVMVMENQRRDPHAWCELIQRHQVTL
                     WNSVPALFDMLLTWCEGFADATPENLRAVMLSGDWIGLDLPARYRAFRPQGQFIAMGG
                     ATEASIWSNACEIHDVPAHWRSIPYGFPLTNQRYRVVDEQGRDCPDWVPGELWIGGIG
                     VAEGYFNDPLRSEQQFLTLPDERWYRTGDLGCYWPDGTIEFLGRRDKQVKVGGYRIEL
                     GEIESALSQLAGVKQATVLAIGEKEKTLAAYVVPQGEAFCVTDHRNPALPQAWHTLAG
                     TLPCCAISPEISAEQVADFLQHRLLKLKPGHTAGADPLPLMNSLAIQPRWQAVVERWL
                     AFLVTQRRLKPAAEGYQVCAGEEREDEHPHFSGHDLTLSQILRGARNELSLLNDAQWS
                     PESLAFNHPASAPYIQELATICQQLAQRLQRPVRLLEVGTRTGRAAESLLAQLNAGQI
                     EYVGLEQSQEMLLSARQRLAPWPGARLSLWNADTLAAHAHSADIIWLNNALHRLLPED
                     PGLLATLQQLAVPGALLYVMEFRQLTPSALLSTLLLTNGQPEALLHNSADWAALFSAA
                     GFNCQHGDEVAGLQRFLVQCPDRQVRRDPRQLQAALAGRLPGWMVPQRIVFLDALPLT
                     ANGKIDYQALKRRHTPEAENPAEADLPQGDIEKQVAALWQQLLSTGNVTRETDFFQQG
                     GDSLLATRLTGQLHQAGYEAQLSDLFNHPRLADFAATLRKTDVPVEQPFVHSPEDRYQ
                     PFALTDVQQAYLVGRQPGFALGGVGSHFFVEFEIADLDLTRLETVWNRLIARHDMLRA
                     VVRDGQQQVLEQTPRWVIPAHILHTPEEALQVREKLAHQVLNPEVWPVFDLQVGYVDG
                     MPARLWLCLDNLLLDGLSMQILLAELEHGYRYPQQLLPPLPVTFRDYLQQPSLQSPNP
                     DSLAWWQAQLDDIPPAPALPLRCLPQEVETPRFARLNGALDSTRWHRLKKRAADAHLT
                     PSAVLLSVWSTVLSAWSAQPEFTLNLTLFDRRPLHPQINQILGDFTSLMLLSWHPGES
                     WLHSAQSLQQRLSQNLNHRDVSAIRVMRQLAQRQNVPAVPMPVVFTSALGFEQDNFLA
                     RRNLLKPVWGISQTPQVWLDHQIYESEGELRFNWDFVAALFPAGQVERQFEQYCALLN
                     RMAEDESGWQLPLAALVPPVKHAGQCAERSPRVCPEHSQPHIAADESTVSLICDAFRE
                     VVGESVTPAENFFEAGATSLNLVQLHVLLQRHEFSTLTLLDLFTHPSPAALADYLAGV
                     ATVEKTKRPRPVRRRQRRI"
     gene            18010..27501
                     /gene="irp1"
                     /locus_tag="LSX49_002605"
     CDS             18010..27501
                     /gene="irp1"
                     /locus_tag="LSX49_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin polyketide synthase HMWP1"
                     /protein_id="HBL7169002.1"
                     /translation="MDNLRFSSAPTADSIDASIAQHYPDCEPVAVIGYACHFPESPDG
                     ETFWQNLLEGRECSRRFTREELLAVGLDAAIIDDPHYVNIGTVLDNADCFDATLFGYS
                     RQEAESMDPQQRLFLQAVWHALEHAGYAPGAVPHKTGVFASSRMSTYPGREALNVTEV
                     AQVKGLQSLMGNDKDYIATRAAYKLNLHGPALSVQTACSSSLVAVHLACESLRAGESD
                     MAVAGGVALSFPQQAGYRYQPGMIFSPDGHCRPFDASAEGTWAGNGLGCVVLRRLRDA
                     LLSGDPIISVILSSAVNNDGNRKVGYTAPSVAGQQAVIEEALMLAAIDDRQVGYIETH
                     GTGTPLGDAIEIEALRNVYAPRPQDQRCALGSVKSNMGHLDTAAGIAGLLKTVLAVSR
                     GQIPPLLNFHTPNPALKLEESPFTIPVSAQAWQDEMRYAGVSSFGIGGTNCHMIVASL
                     PDALNARLPNTDSGRKSTALLLSAASDSALRRLATDYAGALRENADASSLAFTALHAR
                     RLDLPFRLAAPLNRETAEALSAWAGEKSGALVYSGHGASGKQVWLFTGQGSHWRTMGQ
                     TMYQHSTAFADTLDRCFSACSEMLTPSLREAMFNPDSAQLDNMAWAQPAIVAFEIAMA
                     AHWRAEGLKPDFAIGHSVGEFAAAVVCGHYTIEQVMPLVCRRGALMQQCASGAMVAVF
                     ADEDTLMPLARQFELDLAANNGTQHTVFSGPEARLAVFCATLSQHDINYRRLSVTGAA
                     HSALLEPILDRFQDACAGLHAEPGQIPIISTLTADVIDESTLNQADYWRRHMRQPVRF
                     IQSIQVAHQLGARVFLEMGPDAQLVACGQREYRDNAYWIASARRNKEASDVLNQALLQ
                     LYAAGVALPWADLLAGDGQRIAAPCYPFDTERYWKERVSPACEPADAALSAGLEVASR
                     AATALDLPRLDALKQCATRLHAIYVDQLVQRCTGDAIENGVDAMTIMRRGRLLPRYQQ
                     LLQRLLNNCVVDGDYRCTDGRYVRARPIEHQQRESLLTELAGYCEGFQAIPDTIARAG
                     DRLYEMMSGAEEPVAIIFPQSASDGVEVLYQEFSFGRYFNQIAAGVLRGIVQTRQPRQ
                     PLRILEVGGGTGGTTAWLLPELNGVPALEYHFTDISALFTRRAQQKFADYDFVKYSEL
                     DLEKEAQSQGFQAQSYDLIVAANVIHATRHIGRTLDNLRPLLKPGGRLLMREITQPMR
                     LFDFVFGPLVLPLQDLDAREGELFLTTAQWQQQCRHAGFSKVAWLPQDGSPTAGMSEH
                     IILATLPGQAVSAVTFTAPSEPVLGQALTDNGDYLADWSDCAGQPERFNARWQEAWRL
                     LSQRHGDALPVEPPPVAAPEWLGKVRLSWQNEAFSRGQMRVEARHPAGEWLPLSPAAP
                     LPAPQTHYQWRWTPLNVASIDHPLTFSFSAGTLARSDELAQYGIIHDPHASSRLMIVE
                     ESEDTLALAEKVIAALTASAAGLIVVTRRAWRVEENEALSASHHALWALLRVAANEQP
                     ERLLAAIDLAENTPWETLHQGLSAVSLSQRWLAARGDTLWLPSLTPNTGCAAELPANV
                     FTGDSRWHLVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCRC
                     DVGDAGQLATVLDDLAANGGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQL
                     LQTLRNHDGRYLILYSSAAATLGAPGQSAHALACGYLDGLAQQFSTLDAPKTLSVAWG
                     AWGESGRAATPEMLATLASRGMGALSDAEGCWHLEQAVMRGAPWRLAMRVFTDKMPPL
                     QQALFNISATEKAATPVIPPADDNAFNGSLSDETAVMAWLKKRIAVQLRLSDPASLHP
                     NQDLLQLGMDSLLFLELSSDIQHYLGVRINAERAWQDLSPHGLTQLICSKPEATPAAS
                     QPEVLRHDADERYAPFPLTPIQHAYWLGRTHLIGYGGVACHVLFEWDKRHDEFDLAIL
                     EKAWNQLIARHDMLRMVVDADGQQRILATTPEYHIPRDDLRALSPEEQRIALEKRRHE
                     LSYRVLPADQWPLFELVVSEIDDCHYRLHMNLDLLQFDVQSFKVMMDDLAQVWRGETL
                     APLAITFRDYVMAEQARRQTSAWHDAWDYWQEKLPQLPLAPELPVVETPPETPHFTTF
                     KSTIGKTEWQAVKQRWQQQGVTPSAALLTLFAATLERWSRTTTFTLNLTFFNRQPIHP
                     QINQLIGDFTSVTLVDFNFSAPVTLQEQMQQTQQRLWQNMAHSEMNGVEVIRELGRLR
                     GSQRQPLMPVVFTSMLGMTLEGMTIDQAMSHLFGEPCYVFTQTPQVWLDHQVMESDGE
                     LMFSWYCMDNVLEPGAAEAMFNDYCAILQAVIAAPESLKTLASGIARHIPRRRWPLNA
                     QADYDLRDIEQATLEYPGIRQARAEITEQGALTLDIVMADDPSPSAAMPDEHELTQLA
                     LPLPEQAQLDELEATWRWLEARALQGIAATLNRHGLFTTPEIAHRFSAVVQALSAQAS
                     HQRLLRQWLQCLTEREWLIREGESWRCRIPLSEIPEPQEACPQSQWSQALAQYLETCI
                     ARHDALFSGQCSPLELLFNEQHRVTDALYRDNPASACLNRYTAQIAALCSAERILEVG
                     AGTAATTAPVLKATRNTRQSYHFTDVSAQFLNDARARFHDESQVSYALFDINQPLDFT
                     AHPEAGYDLIVAVNVLHDASHVVQTLRRLKLLLKAGGRLLIVEATERNSVFQLASVGF
                     IEGLSGYRDFRRRDEKPMLTRSAWQEVLVQAGFANELAWPAQESSPLRQHLLVARSPG
                     VNRPDKKAVSRYLQQRFGTGLPILQIRQREALFTPLHAPSDAPTEPAKPTPVAGGNPA
                     LEKQVAELWQSLLSRPVARHHDFFELGGDSLMATRMVAQLNRRGIARANLQDLFSHST
                     LSDFCAHLQAATSGEDNPIPLCQGDGEETLFVFHASDGDISAWLPLASALNRRVFGLQ
                     AKSPQRFATLDQMIDEYVGCIRRQQPHGPYVLAGWSYGAFLAAGAAQRLYAKGEQVRM
                     VLIDPVCRQDFCCENRAALLRLLAEGQTPLALPEHFDQQTPDSQLADFISLAKTAGMV
                     SQNLTLQAAETWLDNIAHLLRLLTEHTPGESVPVPCLMVYAAGRPAHWTPAETEWQGW
                     INNADDAVIEASHWQIMMEAPHVQACAQHITRWLCATSTQPENTL"
     gene            27498..28598
                     /gene="ybtU"
                     /locus_tag="LSX49_002606"
     CDS             27498..28598
                     /gene="ybtU"
                     /locus_tag="LSX49_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis oxidoreductase YbtU"
                     /protein_id="HBL7169003.1"
                     /translation="MMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSA
                     RSRELAHAFGIPLYTSPEQITRMPDIACIVVRSTVAGGTGTQLARHFLTRGVHVIQEH
                     PLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLRDAQQLRRCLAKTPQVVHATT
                     SRQLLYSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDD
                     PDMHSLIMHRLLLGWPEGHLSLEASYGPVIWSSSLFVADHQENAHSLYRRPEILRDLP
                     GLTRSAAPLSWRDCCETVGPEGVSWLLHQLRSHLAGEHPPAACQSVHQIALSRLWQQI
                     LRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL"
     gene            28595..29398
                     /gene="ybtT"
                     /locus_tag="LSX49_002607"
     CDS             28595..29398
                     /gene="ybtT"
                     /locus_tag="LSX49_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis thioesterase YbtT"
                     /protein_id="HBL7169004.1"
                     /translation="MTQSAMCIPLWPARNGNTAHLVMCPFAGGSSSAFRHWQAEQLAD
                     CALSLVTWPGRDRLRHLEPLRNITQLAALLANELEASVSPDTPLLLAGHSMGAQVAFE
                     TCRLLEQRGLAPQGLIISGCHAPHLHSERQLSHRDDADFIAELIDIGGCSPELRENQE
                     LMSLFLPLLRADFYATESYHYDSPDVCPPLRTPALLLCGSHDREASWQQVDAWRQWLS
                     HVTGPVVIDGDHFYPIQQARSFFTQIVRHFPHAFSAMTAWQKQPSTSER"
     gene            29402..30979
                     /gene="ybtE"
                     /locus_tag="LSX49_002608"
     CDS             29402..30979
                     /gene="ybtE"
                     /locus_tag="LSX49_002608"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salycil-AMP ligase
                     YbtE"
                     /protein_id="HBL7169005.1"
                     /translation="MNSSFESLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSA
                     LDAQVDELAAGLSSLGLRSGEHVIVQLPNDNAFVTLLFALLRLGVIPVLAMPSQRALD
                     IDALIELAQPVAYVIHGENLAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGER
                     QAWPQPDVSATALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLP
                     VAHNFPLACPGILGTLACGGKVVLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQA
                     REWEDSDLSSLRVIQAGGARLDPTLAEQVIATFDCTLQQVFGMAEGLLCFTRLDDPHA
                     TILHSQGRPLSPLDEIRIVDQDENDVAPGETGQLLTRGPYTISGYYRAPAHNAQAFTA
                     QGFYRTGDNVRLDEVGNLHVEGRIKEQINRAGEKIAAAEVESALLRLAEVQDCAVVAA
                     PDTLLGERICAFIIAQQVPTDYQQLRQQLTRMGLSAWKIPDQIEFLDHWPLTAVGKID
                     KKRLTALAVDRYRHSAQ"
     gene            31110..33131
                     /gene="fyuA"
                     /locus_tag="LSX49_002609"
     CDS             31110..33131
                     /gene="fyuA"
                     /locus_tag="LSX49_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore yersiniabactin receptor FyuA"
                     /protein_id="HBL7169006.1"
                     /translation="MKMTRLYPLALGGLLLPAIANAQTSQQDESTLVVTASKQSSRSA
                     SANNVSSTVVSAPELSDAGVTASDKLPRVLPGLNIENSGNMLFSTISLRGVSSAQDFY
                     NPAVTLYVDGVPQLSTNTIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDST
                     PRGYIEGGVSSRDSYRSKFNLSGPIQDGLLYGSVTLLRQVDDGDMINPATGSDDLGGT
                     RASIGNVKLRLAPDDQPWEMGFAASRECTRATQDAYVGWNDIKGRKLSISDGSPDPYM
                     RRCTDSQTLSGKYTTDDWVFNLISAWQQQHYSRTFPSGSLIVNMPQRWNQDVQELRAA
                     TLGDARTVDMVFGLYRQNTREKLNSAYDMPTMPYLSSTGYTTAETLAAYSDLTWHLTD
                     RFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQLSAGYMLTDDWRVYTR
                     VAQGYKPSGYNIVPTAGLDAKPFVAEKSINYELGTRYETADVTLQAATFYTHTKDMQL
                     YSGPVGMQTLSNAGKADATGVELEAKWRFAPGWSWDINGNVIRSEFTNDSELYHGNRV
                     PFVPRYGAGSSVNGVIDTRYGALMPRLAVNLVGPHYFDGDNQLRQGTYATLDSSLGWQ
                     ATERMNISVYVDNLFDRRYRTYGYMNGSSAVAQVNMGRTVGINTRIDFF"
BASE COUNT         7264 a         9872 c         9091 g         6993 t
ORIGIN      
        1 cgccctatcc ggcccacaca gatcgcatca agttatgttt cgtttgtcat caacctttca
       61 tcaccagaat aatttatttt atttcaataa gatagttcaa tacacctgag aataccatgc
      121 tctcatttcc taatgagttg ttgcattttt tcatatgtta caatataaca ttacacatca
      181 tgtacattaa ctctggagga aattgttttg gcgattcgtc ttcataaact ggctgttgct
      241 ttaggtgtct ttattgttag cgctcctgcc ttttcgcatg gtcatcactc acacggcaaa
      301 cccttaacag aggtcgaaca aaaagctgct aatggtgttt ttgatgatac caatgtacaa
      361 aaccgaacgc tcagtgactg ggatggagtc tggcaatccg tttacccttt actgcaaagt
      421 ggcaaacttg accccgtctt tcagaagaaa gcggatgcag ataaaaccaa aacatttgct
      481 gaaattaaag attattatcg caaaggttat gcgacagata tcgaaatgat tggcattgag
      541 gacggcattg tcgaattcca tagaaataat gaaacaacat cctgtaaata tgattacgat
      601 ggatacaaaa tactcaccta taaatcaggc aagaaaggcg ttcgttactt attcgaatgt
      661 aaagatcctg aaagcaaagc ccctaaatat atacaattta gcgatcatat aattgcacca
      721 cgaaaatcat ctcattttca catttttatg ggtaatgatt cccagcaatc tttattgaat
      781 gaaatggaaa actggccaac gtattatccc tatcagttga gtagcgaaga agtggtcgag
      841 gagatgatgt ctcattgatt tttttgcgct gacttcagtt atttaacaga acagtgcctg
      901 gtagtaacaa caataattta ccaagacaaa taagtaagac aaactcagac acgctcatac
      961 ttgagtcgtg tcttttttat tatgtctgta gaaaaaaact gagaaaaagg cgaacaataa
     1021 atacacaact cagccataca gactggcagc gcaaatgtct ccaggagcaa gtcatctgtc
     1081 atggtaaagc taaccagaaa tataggttaa ttttggtgtt taaacctttt ttacttgtta
     1141 gtatgataca aaggctttca aaaaagctgg gaaattcaac aactcttgga aattatggac
     1201 tttgtcccgc ggctttaatc tgacggccgc gttccttttt tggctcaatt attgacccct
     1261 tctctacgca acttcagttc ccgccagcaa ctttgcggca gtttcatagg atcaatgtct
     1321 aaaagaataa tggtgaccga taagaaaacg actgaataac tgtagatttt cgctcgaaac
     1381 cttcctgtca gacccatagc gaatcaagtg ctgaatgtca cagtatcgaa cagaaaacag
     1441 tgacgatcta acccttcaag aatatcctac gattgttctg tttaggaaaa gcaaggcggg
     1501 aagtcgggag ataagtcatt gataaagtgg cggagagagg gggatttgaa cccccggtag
     1561 agttgcccct actccggttt tcgagaccgg tccgttcagc cgctccggca tctctccgtt
     1621 cagatggttg ccatgatgcc aggaaatttg gcattttaac agtccctgtc cgtgcaattt
     1681 tgttcaagtg acgagtttgc gagcaaaacg atgattaagt ggccctggaa agtacaagaa
     1741 tcagcacatc aaactgccct tccctggcag gaagcactat cgatccccct tttaacgtgt
     1801 ctgacagaac aggaacaaag caaattggtc gctcttgccg aacgtttttt acagcaaaaa
     1861 cggcttgttc ctttacaggg ctttgagctg aattcattaa gaagctgccg gatagcactt
     1921 ctattttgcc tgcccgttct ggagttagga ctggaatggc tggatggttt tcatgaaatc
     1981 ttaatttatc ctgcgccatt tgtggtcgat gatgaatggg aagacgatat cggtctggtg
     2041 cataaccaac gtattgttca gtcaggtcag agctggcagc aagggcctat cgttttgaac
     2101 tggttggata tacaagattc ttttgatgct tctggtttta acctgattat tcatgaagtc
     2161 gctcataagc tggacacccg taacggcgat cgcgccagcg gagttccctt tatttcgttg
     2221 cgtgaggttg ctggctggga acacgatctt catgctgcaa tgaacaacat tcaggaagaa
     2281 atcgaattag ttggtgagaa tgcggcgagc attgatgctt atgctgccag tgatcctgct
     2341 gaatgttttg ccgtactttc tgaatatttc tttagcgccc cagaactttt tgctcctcgt
     2401 ttcccttcat tgtggcaacg tttctgtcaa ttttatcaac aagatccttt gcagagactg
     2461 catcacgcta atgatacaga ctcgttttcg gcgacgaatg ttcattaatt aacaactttg
     2521 cagattaatt aaccaattga aatggcttat gaaatttagt gttgacagac aaggtaccgc
     2581 taagtaatat gcgccccgtt ctcacgattc ctctgtagtt cagtcggtag aacggcggac
     2641 tgttaatccg tatgtcactg gttcgagtcc agtcagagga gccaattttc tgttttcatg
     2701 catccttgcg aatctttatc tgatgttgat tcaacaggtt agtgtgaaaa ctcttctcag
     2761 tgcattttga ttttacccta cgcatcggga aaaattggtg gtcaaatctg gggtcaggtt
     2821 agttcgataa tggagtgacc cccatatgtc ccttaccagc gcaaaaatcc gcaccctcaa
     2881 gccttctgat aaacccttta aagtctccga ttctcacggt ctgtatctgc gggtcaagcc
     2941 gggtggctcc cgccactggt atctcaaata ccgtattagc ggtaaagaat cccgcattgc
     3001 gctgggtacc tatccagcca tctccctgtc tgatgcgcga cagcaacgtg aaggtatccg
     3061 taaaatgctg gcgctgaata tcaacccggt acagcagcgg gctgctgtac gtggctcacg
     3121 aacaccggag aaagttttta aaaacgtggc gctggcgtgg cataaaagta acaggaaatg
     3181 gtcgcagaac accgccgacc gtctgcttgc cagcctgaac aatcacatct ttccggtcat
     3241 cgggaaccta cctgtatcag aacttaaacc ccgtcatttc attgacctgc tgaaagggat
     3301 cgaggaaaaa ggtctgctgg aggttgcgtc ccgcacacgg cagcacctga gtaacataat
     3361 gcgccatgcg gtccatcagg agttaatcga tacgaaccct gcagcaaacc ttggcggcgt
     3421 gaccacacct cctgtcagac ggcactatcc tgccctgccg ctggagcggc tgcctgaact
     3481 gcttgaacgt attggggcat atcatcaggg ccgtgaactg acccggcatg ccgttctgct
     3541 gatgctgcat gtgttcattc gctccagtga actgcgtttc gcccgctggt cagagattga
     3601 tttcacaaac cgagtctgga cgatacccgc gacgcgagaa cccattattg gcgtgcgtta
     3661 ttccggccgc ggggcaaaaa tgcgaatgcc gcatatcgtc cccctctcag aacagtccat
     3721 cgccattctg aaacagatta aggatatcac cggtaataat gaactgatct tccccggcga
     3781 ccataacccg tataagccaa tgtgtgaaaa cacggtcaat aaggcactgc gggtgatggg
     3841 ttacgacacg aaaaaggata tctgcggtca cggcttccgg gcaatggcat gcagtgcgct
     3901 gatggaatcg ggtttatggg caaaggacgc agtagaacgc cagatgagtc atcaggagcg
     3961 caataccgtg cgcatggctt atattcataa ggcagagcac ctggaagccc gcaaagcgat
     4021 gatgcagtgg tggtcggatt atctggaagc atgccgagaa tcttatgcac cgccttatac
     4081 aattggtaaa aataagttta tcccatagta tactaacgaa tcccacactc tggcaaatta
     4141 ccaccacctc cacaagaggt ggttctatat agacttttat caacttcatg acgaaaaaca
     4201 cctattttat cccaaaagaa gacaatagag tcacagagga atcaaagagc gactcaattg
     4261 tctttggaca gtctggttgt gaggttagaa aacagttact cctacaccat taaatagggc
     4321 gcaatgctcg ctaatttctc ccgggtttct gtcagttcgc gttccggcgt agattgcgcg
     4381 atgattcccg cccccgcctg tatccagcag cgctggctat cctgaaatac ggaacgcaga
     4441 actagcgccg catcaaagcg cgtatcgtcc agcagcagga ttgcgccgga ataaagctct
     4501 cgcggcgtct tctcaatttg cataatcgcg ttcagagcag catttttagg gatacctgag
     4561 gcggtaatcg acggaaacag cacggtaaac gcatcccagg catccttgtt ttccgcaagc
     4621 tgaccgctca cgccagaccc cagatgctga acgctgccgc gctggcgaac cgacattaaa
     4681 tcttcaacca ccacgctgcc cggctggcaa acggcctcca gttcagcaat agcttctttg
     4741 acagaaagga tatgctcaag cacctcttta ctgtcgtgca gcagttctgc ctctttcgcc
     4801 ttattatgct ccgggtttcc catgcgatcg cgggtgcccg caagcggttc agtgaccact
     4861 ttattgcccg tcactgacat caccagttct gggctaaagc ccagcgcttc gcgtccttcc
     4921 tgacggaaca taaacgagcg cacaggcgtg tttgcctgcc gcccgtataa cagcgtggcg
     4981 ggcatatcaa tccgcgatgg caggggaatg gcgcgcgaga caatcacttt gacatactcg
     5041 ccacggcgga tctccgcaac ggcgcgcgca acctgttgtt tatatgcctc accattgagg
     5101 gcggtatcca ccgccagtgg tgcgttctgc gtcgttgtac cggcctcttt tacccactcg
     5161 cacaaacgtc ggcacccgtc ggcggagtcc gcataaacgg tgacatttcc cttttcaaaa
     5221 ataagttctt cacggggaac ggttaacgtc agcagcggcc actccccggc gttaaaggca
     5281 atcccccgcg catgcgccgc aaagttgaac ccaacctgtc catatacccg acgtcctttc
     5341 acctgaggat gcgccataaa acgacgcgcg cagtcggcaa tggaatccac cgcccatttt
     5401 tgctccccgg catcatcaat aaatgtcgcc tgcgttccgt cggcattaat gtgcagccgt
     5461 gcctggcacc ctttgcctaa ataccaacag ggttgacgct catagacata acactcttct
     5521 tctgcgaact ggcgtaaaac gccagaaatc gtcggtagcc attgttcctc tggtaacgcc
     5581 agatgtagaa attcactgat tttcatccct tacctctctg tgttattcgc ggatcaatca
     5641 attgcgcttg tcatcagttc tcttgccgaa tgcagccgga tataagcaac ccacgccgcc
     5701 agcaacgtga atgccccggc aaacaggaag caggccgcat agccaaaatg ttgagcaaca
     5761 acgccaccga taacgcctgc cagaatggcg attgccgcat cagtacattg aaagagggtg
     5821 aagtcgacac cggcctgcaa aggcgatgaa agcgacatca gcgtggcgta aagacagacc
     5881 agcgcgcagg ccagcgaaat ggactggaca atgaccagac actggagaat ctgcagcagc
     5941 agatgacccg gcgccatcat gagcgtcatc accaccgcca gcagcgcgat cccctggacg
     6001 ccataagccg tcaacagcgc tctgccgggt gaggtgtatt tcatcagcaa tccgccggcc
     6061 agcgttcctg ctatgcccgc tgcaatattg ccgccgctga acagcgcgcc caatgcggac
     6121 atgctcaacc catgatccaa caacagcggt gccagaagag gcagcacaaa ccgcatgcct
     6181 gaattcagca tcaataccag cagtaagccc aggcgcgcct gcttcctcct tagcgcataa
     6241 cctaacgccg gaacatgcgg gatagtcgct gttcgcgtcg gctccgtaat gcgccacagc
     6301 gggagtgaca gcgccataat cagcaccgcc atcatcagca tggcgacagg ccagccggat
     6361 gccgccgaca gcatcatgaa caccccgccg ccgcacatca ttcccagata gctgccgccg
     6421 acctgcacgc tgtttcccca gccgtaaccc gtgcgggtca gttgatcgac acaaaagccg
     6481 tcgctggcga tatcaatggt ggaggcgacc gtgcctgcca ccataaacag aacaaataac
     6541 gcgacgattt gcgtatcggg gaatccccct tctcgcccaa accagccaat cgctgcggca
     6601 atagtcagga tcgccgctag cgcgacctga ccacgcagga ttaacatgcg ggaacggcgt
     6661 tcctggctac cgggcggaag ccgccagcgc tcgatccacg gcgcccaaat aaacttcagc
     6721 gcccagggca gcataaacag ggttgtcgca ccggcaagcg ccagcgaacc gccagcagcg
     6781 cgcaccagcg cgggtaagga ctgcatagac agcgccgata ccagactctg cgtcacatag
     6841 acgccggcaa tagcaaaaat cacccgcccg gtcgtcaacg tcagcggttt cacattcgac
     6901 tgaacatcac tcatgccccc actctccaga cgcggaaacc ccgtcgtcgc gccacacgcg
     6961 cgcggccatt tgcgcctgcc acagcgcctg ataacgtcca tgatgtgaga gcaattgcgc
     7021 atgagtaccc tgctcaacca cctgtccctc ttccatcacc agaatgtttc cggccccggc
     7081 gatggtggat aaacggtgag cgatgataat caccgtccgg ttgtaaacca ggttatcgat
     7141 cgctttttgc accgccagct cgctttcaat atccagcgcg gcagtcggtt catcgagaat
     7201 aacgaccggc gcgtttttca ataacgctct ggcaatggaa atccgctggc gctcgccgcc
     7261 cgatagctgg ccgcccatct ctcccattgg cgtcagccag ccttgcggaa gacgggaaat
     7321 aaactcaagg cactgcgccg cgcgggcggc ctcttctacc tcctgccgcg tcgcctgtgg
     7381 gcgcgcgata cggatattcg ccagcagcgt gtcatcaaac agccagacat cctggaaaac
     7441 aacagaaatc aggctattga gctgttccgg cgtcaggcgg cgaatatcga cgccgccaat
     7501 agaaatctgc ccttgctgcg gatcggcata gcgcattaac agtttggtga cggtagtttt
     7561 gcctgcgccg gaggcaccca ccagcgcgct catactggct gccgggaacg tcaaagaaac
     7621 atgattaagc gcgtggccgt caccttcttc gtagcgatag ctgacgttgt caaagcggat
     7681 atcgtaacgt tccggcatct cgctttgctc tgcgacggga agcggtgcta tcgccataaa
     7741 ctgctcaatc ctttgcaggg cgctggcgat cagttccaca accgaggtgt agctgataaa
     7801 catcgccatc ggttctgcga agcgcataat catcgcgacg gcggcaatca aaaaggcgag
     7861 gttcagagtg cccgtcacta cccagacgat cccggataac accaccacct gtaggcccaa
     7921 ctccacgacg ctggcgatca gcatcgtcgc gccagcgccc tgacggtgag tgcgggtctg
     7981 taagttttcc agcgcattga aatgcgccag cagcgcccgg cttttatcgg catcgctgcc
     8041 gcaggtgcgc aataccatca tcccctgagc aaattcaacg atatcgccgc tcagacgctg
     8101 gtgcgcttcc cccagcgtct gcatttgtcg ccgcatcgcc gggcggcgcc agtaataaaa
     8161 cggcaccagc agagggaaga tcagcaacat caccagcccc agccgccagt ctatccacaa
     8221 tgtcgccagc gacgccgtca gcggcgtgac aatggtgagc agcaaaatat tggctatcgc
     8281 aataacataa ttgaggtttt catccacgct gcccagcagc aaggcgttca tttcacccgc
     8341 cctgccgcgc tggagcttct ccagcggcac gcggcgtaac tgctcgccaa gtcgcaggcg
     8401 caactcatgg gtagcctgcg ccagatgacc acggtattca aagcccaggc cataccagcg
     8461 tagcaccagc gtcacaattg cggcgacgct gaaggccata gcccagttaa gaagttgcgg
     8521 cgcgtctccc cgtaacagcg catcaatgat cggataaaga caggcaaagg cgatcccctg
     8581 catgaatgcc gccagcaaca gcgccagcat actgcgtcgc agcatcctgg cctgactgcc
     8641 aacgctggag ataagctggc gccagatgac gcgccaggcc aggttatccg caggattatt
     8701 gtctttcatt ttccatcacc tcttcctgtg ttccacccgg cacccaatgc tgcgcctgct
     8761 gatagtgttg ccagagccgt tgatacaggc cgccctgcgc caacagttgc gtatggttcc
     8821 ccatttccct gagctgtccg tcggaaaaca gcaatatcac atcggcctga gtcaccattg
     8881 agagacgatg cgcgaccatg atgaccgtcc ggccacgcat ggccgccgcg agcgccttga
     8941 taagcgccgc ttcgttttcc gggtcagcaa acgccgtcgc ctcatcgagc accaggatgg
     9001 ggcgatcctg caaaagcgcc cgggcgatag taatgcgctg ccgctggccg ccggagagaa
     9061 ataccccacg ttccccgact cgagtgttgt aaccttctgg cagagcgcta ataaaatcat
     9121 gggcctgcgc cactctggcc gccgctataa ccgcctccag cggcgtatcc ggcgcgccca
     9181 gacgaatgtt attggctatc gtgtcggcaa aaaggaagtt gtcctgaaac acaaacgaga
     9241 gttgcttcat cagggtgtcc gtctgcatat cacgcagatc cacgccgcca atacggatat
     9301 ggcctttgtc cgggtcggcg taacgcagca gcaagcgcac cacggtgctt tttccggcgc
     9361 cgcttggccc gaccagcgcc acaatttgcc cggcaggcac atgaaagctc acctcctgca
     9421 acgcggcgcc agtacgcgct tgcggataat gaaagctcac ctgctcaaag gtaatgctcg
     9481 cctcttgcgg ctgctggtca gactgcggca gcgataactc cggcatcgcg agaacctgat
     9541 aaatacgctg aatgcttaaa cgcgtttgcg cgaccaggtt attgagcatc atcattggca
     9601 ttacggcttc ggccattccg ctgcccagca gtaaaacggc cacccacgcg ataaaatcga
     9661 aactgccata gtgcaacagg ccgtatcccg accagatcag gacaaacagg gtcgggagag
     9721 gattcagaat cgagaaggaa aaacgcgctg aaaaaccggc tttgcgatac caggttttga
     9781 gcacatcgac ccactcttca agggcgcgtt gatagcgcaa aaaactggtg ctgccgctat
     9841 caaacgttct caccacgggc atggcctgca cgaactcaat aaccgccgcg ctaacctgct
     9901 cgcgcgcctt atgataacgc tgagccatat cttccgaacg ctggcgggcg agcacgagaa
     9961 caaccgatcc aaacgccagt acccccagcg tcgcgattgc cagccgccag tccagccaga
    10021 acaagataac gattgtcgcc agcggcatga tgatcgcgcg ggcatagagc ggcgtgctgt
    10081 cggccacaaa aatatgtaac gacttcacgt catccagcat cactttcgcc actgacccgc
    10141 tgcccatttg ctgtaacacg ccaggcggaa gctgcaatgc tttacgggct aacctgctgc
    10201 gcagaatgtt ctccagatga aaagccgcgt aatgagaggt gttgaacgcc tgtaagcgca
    10261 gaacaaaagt taagaccacg cagccgatca cgccgcccag cggccaggcc ggaatagcgt
    10321 caggcgtcgc gcgaatgtca cgcaggctcc acgccagaaa aaggagcgcc cccaggctgg
    10381 ttaatgccgc cagccccgcc agcgccatag ctaaaataac cttcctgcga accggtgtaa
    10441 tcacctgcca aagaggaaat cgggacagcg attcagtatt ggatgattga gatgacatgg
    10501 gagtaactga atttcctgat gaatttttac ggacgccaaa aacgacaatt cagggtggcg
    10561 ttctgagaat taatgtgaat aataaccatt atcaataact catctacccc attcggttct
    10621 atttataccc gcattggtct aagccacagg gagataacca ggtcatgacg gagtcaccgc
    10681 aaacgcaatc tgaaatctct attcaccagt tggtggtcgg gaaacctgca aacgatggca
    10741 atattcctgc tcagtgtgaa ctgctgcgct gttcgttgca ggaaggtatg gatattttgc
    10801 tctggagggg ccattttgcg cggcctgaga cgttgcagct acacgacgat ctgggcagga
    10861 ttaacttctc gtgcatcctg gaaggcacat cgcgctttgc gattcaggga ctccggcgtc
    10921 acaccgactg ggagcttgcg cgcaatcgcc attacattac ccatacgcca gactgtcgcg
    10981 gcagcgcctc ctattgtggc cgattcgaga gcattaccct ctccttcagc cctgaaaccc
    11041 tcgcgctgtg ggtgccggat attagcgcgg tcattaagaa taagatcgac tcccactgct
    11101 gttgccagca gcaccgttgt aatgctgaaa cccacttaac ggctcaggcc ttgcgtcacg
    11161 cgctgatgcg catgcacagc ggcttcagtc atgaacaaaa gccgtcgacg ctatggttgc
    11221 aggggcaaag tctggtcatg ctcagtctgg tgctggatga acatcgcgaa gacgccagtt
    11281 gcctctcctg ccacttcacc ccgatggaac gccagaaact gctgcgggcg aaggatctgc
    11341 tgctggctga tctgacgcaa gcgccgggcg tcgcggagct ggccagagag tccggtctga
    11401 gcgttctcaa aattaagcga ggcttccgcg ttctgttcaa caacagcgtc tatggcctgt
    11461 ttcaggctga acgaatgcag gaagccagaa gacgcctggc caacggcaat acctccgtca
    11521 tgacggtggc ggccgatctg ggctatgcca acgccagcca tttctctgcc gccttccaga
    11581 aacagtttgg cgtaactcct tcgaccttta aacgcgggat gtaaccgggg tcgcgccccc
    11641 ctaaactcct ccctgacaga ggcccggata ccccatcagg gcctctgttc tttccgcctg
    11701 ttaccaaccc gaaacgggca taaataaacc cgtttcgggt agcatccaat tgttaataat
    11761 tattattctc atatgagtaa tgcttttcgg taagacgtgc catcaggagg aagaatgatt
    11821 tctggcgcac catctcagga ttcgctgtta ccggacaacc gccacgcggc tgattaccaa
    11881 caattacgcg agcggctcat acaggaactg aatttaacgc cgcagcagtt acatgaagag
    11941 agcaacctga tccaggccgg cctggattcc ataagattga tgagatggtt acactggttt
    12001 cgtaaaaatg gctaccgcct tacccttcgc gagctgtatg ccgcccccac gctggcggca
    12061 tggaaccagt taatgctcag ccggtcgccg gagaacgcgg aagaagaaac gccgcccgac
    12121 gaatcatcct ggccgaacat gaccgaaagt acccccttcc cattgacgcc agtacagcac
    12181 gcctacctga cgggccgcat gccggggcag acgcttggcg gcgtgggttg ccacctgtat
    12241 caggagtttg aaggccattg tctgacggcg tcgcagctgg agcaggccat cacgaccttg
    12301 ctgcaacgcc acccaatgct gcatatcgcc tttcgccccg acgggcagca ggtctggcta
    12361 ccgcaacctt actggaacgg cgtcaccgtt catgatttac gccataacga cgctgaaagc
    12421 cgccaggcct atctggacgc actgcgccag cgcctgagcc accgtctttt acgcgtggaa
    12481 atcggcgaaa cgtttgattt tcagctgacg ctcttgccgg acaatcgcca ccgcctccat
    12541 gtcaatattg acctgctgat tatggatgcc tccagcttta cgcttttctt cgatgagctt
    12601 aacgccctgc tggccggaga atcgctgccg gctatcgaca cccgctatga tttccgctcg
    12661 tatttgctgc accagcagaa gatcaatcaa ccactgagag acgacgcgcg cgcttactgg
    12721 ctggcgaaag catcgacgct tccccccgcg cccgtcttgc cgctggcctg cgaacccgcc
    12781 acgctacgtg aagtccgtaa tacccgacgc cgcatgattg tcccggcaac acgctggcac
    12841 gcctttagca accgggccgg cgagtatggc gtgacgccga caatggcact ggcgacctgt
    12901 ttttctgccg tgctggctcg ctggggcggc ctgacgcgtc tgctgcttaa catcacctta
    12961 ttcgaccgcc agccgctgca cccggcggtt ggcgcgatgc ttgccgactt caccaatatt
    13021 cttctgctgg ataccgcctg cgatggcgat accgtcagca acctggcgcg taaaaaccag
    13081 ctcacgttta cggaggactg ggagcatcgc cactggtccg gcgtcgaatt actccgtgaa
    13141 ctcaaacgcc agcagcgcta cccccacggc gccccggtgg tatttaccag caatctgggg
    13201 cgttccctct acagcagccg cgcagaatcg ccgttgggcg agccggaatg gggcatctcg
    13261 caaacgccgc aggtctggat agatcatctg gcgttcgagc atcacggcga ggtctggcta
    13321 caatgggaca gcaacgacgc gctgttccct ccggcgttag tcgaaacatt gttcgatacc
    13381 tactgccagt tgattaacca actctgcgat gacgaaagcg cctggcaaaa gccgttcgca
    13441 gatatgatgc ccgccagcca gcgcgcgata cgcgaacggg tcaacgccac cggcgccccc
    13501 attcccgaag gcttgctgca tgaaggcatt ttccgtatcg ctctgcaaca gccgcaggcg
    13561 ctggcggtaa cggacatgcg ttatcagtgg aattatcatg agctgacaga ctatgcccgc
    13621 cgttgcgcgg gcaggttaat cgagtgcggg gttcagcccg gcgataatgt ggctatcacg
    13681 atgtcgaaag gtgcaggaca acttgttgcg gttctggccg tcctgctggc tggggcggtt
    13741 tacgttccgg tttcgctgga tcagcctgcc gcacggcgcg agaaaatcta cgctgacgcc
    13801 agcgtccggc tggtgctcat ttgtcagcac gacgccagcg ccgggtcaga cgatattccc
    13861 gtccttgcct ggcagcaggc cattgaggcg gagccgatcg ccaacccggt agtacgcgcc
    13921 cccacgcaac cggcctacat tatctacacc tccggctcta ccggtacgcc gaaaggggta
    13981 gtcatttctc accggggagc gcttaacacc tgttgcgata tcaatacccg ctatcaggtt
    14041 ggcccgcatg acagggtgct ggccctctcc gccctacatt ttgatttatc ggtttacgac
    14101 atttttggcg tactgcgcgc gggcggcgcg ctggtgatgg tgatggaaaa tcaacggcgc
    14161 gatcctcacg catggtgtga gctgatccag cgccatcagg tcacgctctg gaacagcgtc
    14221 ccggcgctgt tcgatatgct gctgacctgg tgtgaaggtt tcgccgacgc cacgccggaa
    14281 aacctgcgcg cagtgatgct ttccggcgac tggatcgggc ttgacctccc cgcccgttat
    14341 cgggccttcc ggccacaagg acaatttatc gcgatgggcg gtgccaccga ggcgtctatc
    14401 tggtctaacg cctgcgaaat tcacgacgtc cccgcccact ggcgctccat cccttacggt
    14461 tttccgctaa ccaaccaacg ctaccgggtg gtggatgaac agggccggga ctgccctgac
    14521 tgggtgccgg gtgaattatg gattggcggc attggggtcg cggaaggcta tttcaacgat
    14581 cccctgcgta gcgagcagca atttttgacg ctcccggacg agcgctggta tcgcaccggc
    14641 gatctcggct gctactggcc agatggcaca atcgagttcc tcggtcgtcg cgacaagcag
    14701 gtcaaagtcg gaggatatcg catcgagctg ggcgaaatcg aaagcgcgct cagccagctg
    14761 gcgggggtga aacaagcaac cgttctggcg atcggcgaaa aagaaaaaac gctggcggca
    14821 tacgttgttc ctcagggcga ggctttttgc gttaccgatc atcggaaccc ggcactgccg
    14881 caggcgtggc acacgcttgc gggaacgttg ccctgttgcg ccatctcgcc agagatctcc
    14941 gcagaacagg tagccgattt ccttcagcat cgcctgctaa aactgaagcc gggtcacacc
    15001 gctggcgccg atcctctccc cctgatgaac tcactcgcta tccagccgcg ctggcaggcc
    15061 gtggtggaac gctggttagc atttctggtg acacaacggc gactgaagcc cgctgctgaa
    15121 ggttatcagg tctgcgctgg tgaagaacgc gaggatgagc acccgcactt cagcggacat
    15181 gatttaacgt tatcgcaaat tcttcgcggt gcccgtaacg aactgtcgtt actgaacgac
    15241 gcgcagtggt cgccggaaag cctggccttt aaccatccgg ccagcgcccc gtatattcag
    15301 gaactggcga caatttgcca acagcttgca cagcgcttac agcgcccggt gcgcctgctt
    15361 gaggtgggaa cccgcactgg ccgcgccgca gaatcgctgt tagcacagct caacgccgga
    15421 cagattgagt atgtcgggct tgagcagagc caggagatgc tgctgagcgc ccggcagagg
    15481 ctcgccccct ggcctggcgc ccgtctgtcc ctctggaatg cagacacgct ggcggcgcac
    15541 gctcactcgg cggacattat ctggcttaat aacgccctgc atcgtctgct gccggaagat
    15601 cccgggctcc ttgcgacatt acaacagctt gccgttcccg gcgcgctgct ctacgtgatg
    15661 gagtttcgcc agttaacgcc gtccgcccta ctcagcacgc tcctgttaac caatgggcag
    15721 ccggaggcct tgctgcataa cagcgccgac tgggcggcat tatttagcgc ggccggcttc
    15781 aactgtcagc atggcgatga ggtcgcgggg ttacaacgct tcctcgtaca atgtcctgac
    15841 aggcaggtgc gccgcgatcc ccgtcaactt caggccgccc tcgccgggcg tctgccgggg
    15901 tggatggtgc cgcaacggat cgtcttcctc gacgccttac cgctgacggc taacgggaaa
    15961 attgactacc aggcgctgaa gcgtcgtcat acccctgaag cggaaaaccc ggccgaagcg
    16021 gatttacccc agggcgacat tgaaaaacag gttgccgccc tctggcagca actcttatca
    16081 actggcaatg tcaccagaga aaccgacttc ttccagcaag gcggcgatag cctgctggcg
    16141 acccgtctga ccgggcaact tcatcaggca ggttatgaag cgcaattaag cgacctgttt
    16201 aatcatcccc ggctggcgga ttttgccgcc acgctgcgga aaaccgacgt cccggtcgaa
    16261 caaccattcg tccactcccc tgaagatcgc taccagccct ttgcgcttac cgacgtgcag
    16321 caggcttacc tagtggggcg tcagccgggc tttgccctgg gcggcgtcgg ctcacatttc
    16381 tttgttgaat ttgaaattgc cgatctggat ctcacccggt tggagacggt ctggaaccga
    16441 ttaatcgccc gccacgatat gctacgcgcc gtcgtgcgtg atggacagca acaggtgctc
    16501 gaacagacgc ctcgctgggt aatacccgca cacatcctcc atacgcctga agaggcgttg
    16561 caggtgcgcg aaaaactggc ccatcaggta ctcaaccccg aagtctggcc ggtattcgat
    16621 ctccaggtcg gttacgttga cgggatgccc gcccgcctgt ggctgtgtct ggataacctg
    16681 ttacttgacg ggctgagcat gcagattctg ttggcggagc tggagcacgg ctaccgctac
    16741 ccgcaacagc tgcttccgcc gctgcccgtc accttcaggg attatctgca acaaccctcg
    16801 ctacagtcgc ccaatccaga ttctctggca tggtggcagg cgcagcttga tgatattcct
    16861 ccggcgcctg cgttgccgct gcgctgcttg cctcaggagg ttgaaacacc gcgcttcgcc
    16921 cgcctgaacg gcgcactgga cagcacgcgc tggcatcggc tgaaaaaacg ggcggctgac
    16981 gcccatctca ccccgtcggc cgtactgttg tcggtgtggt caacggttct ctctgcatgg
    17041 agtgcacagc ctgagttcac gcttaacctt acgcttttcg acaggcgacc gctgcacccg
    17101 caaatcaacc agattctggg cgatttcacc tcgctgatgc tgctgagctg gcatcccggc
    17161 gaaagctggc tgcacagcgc gcagtcacta cagcagcggc tgagccagaa cctcaaccac
    17221 cgcgatgtgt cagccatccg cgtgatgcgt caactggcgc aacggcaaaa cgtgccagcc
    17281 gttccgatgc ccgtcgtctt taccagcgcg ctgggctttg agcaggataa cttcctcgcc
    17341 cggcgtaatc tgctcaaacc ggtctggggc atctcccaga cgccgcaggt ctggctcgat
    17401 caccagattt atgaatccga aggcgaactg cgctttaact gggattttgt cgccgcgctg
    17461 tttcctgccg ggcaggtgga gcgccagttt gaacagtatt gcgcattgct aaaccgaatg
    17521 gccgaggatg aaagcggctg gcaactgccg ctcgccgcgc tggtgcctcc cgttaaacac
    17581 gcagggcaat gcgcagagcg ctcaccgcgc gtatgccctg agcactctca gccacacatt
    17641 gcggcggacg agagcaccgt cagcctgatt tgcgacgcct tccgcgaggt ggttggcgag
    17701 tctgtcacgc ccgcagaaaa cttctttgag gcgggcgcaa cgtcgctgaa tctggtgcaa
    17761 ctgcacgttt tgttacaacg tcacgaattt tccaccctga cgttgcttga cctcttcacc
    17821 cacccttctc ctgctgccct ggccgattat ctggccggcg tcgccacggt ggagaaaaca
    17881 aaacgacctc gccctgttcg ccgtcgtcag cggcggatat agcgcgaagc aaactgattt
    17941 tccccggaac gccatcgcga acgcatggcg ttccattgac tttgtgaatc ttaggaaacg
    18001 ggaccgatta tggataactt gcgcttctct tctgcgccga cagcagattc cattgatgca
    18061 tcgatcgctc aacactaccc ggactgcgaa cctgtcgcgg ttatcggcta cgcctgccat
    18121 tttcctgaat cgccggatgg cgaaacgttc tggcaaaatc tgctggaagg tcgtgaatgc
    18181 agccgacgct ttacgcgcga agagcttctg gccgtcggtc tggatgccgc catcattgac
    18241 gatcctcatt atgtcaatat cggtacggtg ttagacaacg ccgactgctt cgacgccacc
    18301 ctgtttggct attcgcgaca ggaagcggag tcgatggacc cgcagcagcg cctgtttttg
    18361 caggcggtct ggcatgcgct ggaacatgcc ggttatgccc ccggcgccgt cccccataag
    18421 accggcgttt tcgcctcttc ccggatgagt acctaccccg gtcgcgaagc attgaacgtg
    18481 acagaagtcg cgcaggtaaa aggtctgcaa tctctgatgg gcaatgataa agactatatt
    18541 gccacccgcg ccgcgtacaa actcaacctg cacggcccgg cgttatcggt acagaccgcc
    18601 tgctccagct cgctggttgc cgtgcatctg gcctgtgaaa gcctgcgcgc aggcgaatcc
    18661 gatatggcgg ttgccggcgg cgtggcgctc tctttccccc agcaggcagg ctaccgctac
    18721 cagcccggaa tgattttctc tcctgatggt cactgtcgtc cctttgacgc ctcggctgag
    18781 ggcacctggg ccggtaacgg tctcggctgc gtggtgctgc gtcgcctgag agacgcgctg
    18841 ctgtcaggcg atccgattat ctcggtgatc ctctccagcg cggtcaacaa cgacggcaac
    18901 agaaaggtcg gctataccgc cccttccgtc gcagggcaac aagcagtcat cgaagaggcg
    18961 ttaatgctgg cggccatcga cgacaggcag gtaggttaca ttgaaaccca cggcaccggc
    19021 acaccgctgg gcgacgcgat tgaaattgaa gcgttacgca acgtctatgc gcctcgcccg
    19081 caggatcagc gctgtgcgct cggttccgtg aaaagtaaca tgggccatct ggataccgcg
    19141 gcgggcattg ccggactgct gaaaaccgtt ctggcagtca gtcgcgggca aattcctccc
    19201 ttactgaatt ttcacacccc caacccggcg ctgaaacttg aagagagccc ctttaccata
    19261 ccggtgtcgg cacaggcatg gcaggacgaa atgcgctatg cgggcgtctc ctcctttggt
    19321 attggcggca ccaactgcca tatgatcgtc gcctcgctgc ccgacgcgct caacgcgcgc
    19381 ctccccaata cggatagcgg cagaaaaagt accgcgctgc tgctcagcgc cgccagcgac
    19441 agcgcgttgc ggcggctggc gacggattat gccggggcgc tgagagagaa tgcggatgcc
    19501 agctctctgg ccttcacagc cctgcacgcg cgccgtctcg atctcccctt ccgcctggcg
    19561 gcgccattaa accgtgaaac cgccgaggcg ctcagcgcct gggccggtga gaaatcgggg
    19621 gcgctggttt acagcggcca cggcgccagc ggcaagcagg tgtggctgtt taccggccag
    19681 ggctcgcact ggcgcactat gggtcaaacg atgtaccagc actcaacggc gtttgccgac
    19741 acgctggatc gctgtttttc cgcctgtagc gaaatgctca cgccgtcact gcgcgaagcg
    19801 atgtttaacc ccgattcggc gcagctggac aatatggcct gggcgcagcc ggcgattgtc
    19861 gcgtttgaaa tcgcgatggc ggcgcactgg cgtgctgaag gactgaagcc agacttcgcc
    19921 attgggcatt ccgtcggtga atttgccgct gccgttgtct gcggacacta tacgattgaa
    19981 caggtcatgc cactggtttg tcggcgcggc gcgctaatgc agcagtgcgc aagcggcgcg
    20041 atggtggcgg tatttgcaga cgaagacacg ctgatgccgc tggctcgcca gtttgagctg
    20101 gatctcgccg ccaacaacgg tacgcaacat acggtatttt ccgggccgga agcccgtctc
    20161 gcggtatttt gcgccacgct ctcgcagcat gacattaact atcgtcgcct gagcgtaacc
    20221 ggtgcggcgc actccgcttt actggagccg atactcgatc ggttccagga cgcctgcgcg
    20281 ggactgcacg cggagccggg gcaaataccg attatttcca cgctcaccgc cgacgtcatt
    20341 gatgagtcaa cgctcaacca ggcggattac tggcgccgac acatgcgcca gccggtgcgt
    20401 tttatccaga gtattcaggt ggcgcatcag ctcggcgccc gcgtttttct ggagatgggg
    20461 cccgatgccc agttggttgc ttgcgggcag cgcgaatacc gcgataacgc atactggata
    20521 gccagcgccc ggcgtaacaa agaggcgagc gatgtcctca atcaggccct gctccagctt
    20581 tacgctgccg gcgtcgccct accgtgggcc gacctgctgg cgggcgatgg acaacgtatc
    20641 gctgcgccat gttatccgtt tgatactgaa cgttactgga aagagcgcgt ctccccggcc
    20701 tgcgagcctg ccgacgcagc gctgtctgcc gggctggagg tggcgagtcg cgccgcgaca
    20761 gcgctcgatc tccctcgcct ggatgcgctt aaacagtgcg ccacgcgact gcacgccatc
    20821 tacgtcgatc aactggtaca acgctgtacc ggcgatgcca ttgagaacgg cgtggacgcc
    20881 atgaccatca tgcgccgtgg acgtctgctg ccccgctacc agcagctact ccagcgcctg
    20941 ctgaataact gcgtggtcga cggcgattac cgctgcaccg acgggcgata cgtccgcgcc
    21001 cgccccattg aacatcaaca gcgggaatca ctgctgacgg aacttgccgg ttattgtgaa
    21061 ggttttcagg ctattcccga caccatcgcc cgtgccggcg atcggttata tgaaatgatg
    21121 agcggcgcgg aagaaccggt ggcgattatc ttcccgcaaa gcgcctccga cggcgtggaa
    21181 gtgctgtatc aggaattcag ctttggccgc tatttcaacc aaatcgccgc cggggtatta
    21241 cgcggcattg tccagacgcg tcagccccgc cagccgttgc gtattcttga agttggcggc
    21301 ggaaccggcg gcaccaccgc gtggctgctg ccggaactca acggcgttcc ggcactggag
    21361 taccatttca ccgatatctc ggcgctgttc acccgtcgcg cccagcagaa attcgccgac
    21421 tatgattttg tgaagtatag cgagctggat ctcgaaaaag aggcgcagtc tcagggtttc
    21481 caggcacagt cttacgatct tatcgtggca gcgaacgtga ttcacgccac ccgccatatt
    21541 ggccgcacgc tcgataatct gcgccccctg ctcaagccgg gcgggcgcct gctgatgcgc
    21601 gaaatcaccc agccaatgcg tctgtttgac ttcgttttcg gcccgctggt tcttccgcta
    21661 caggatctcg acgcccgcga aggtgagtta ttcctcacca ccgctcagtg gcaacaacag
    21721 tgccgccacg ccggattcag caaagtggcg tggctaccgc aggatggcag cccgaccgcc
    21781 gggatgagcg aacatatcat tctcgccacg ctgcccggtc aggcggttag cgccgtaaca
    21841 ttcaccgcgc catcagaacc cgtgttgggg caggcgctga cggataacgg tgattatctc
    21901 gccgactggt ctgattgcgc aggtcagccc gaacggttta acgcccgctg gcaggaggca
    21961 tggcgtctgc tttcacagcg tcatggcgac gctctgcctg tggaaccgcc ccccgtcgcc
    22021 gccccggagt ggctggggaa ggttcgctta agctggcaaa acgaagcctt ttcccgcggt
    22081 cagatgcgcg ttgaagcccg tcatcctgct ggcgagtggc tgccgctatc gcccgccgcg
    22141 cctcttcctg cgccgcaaac gcattatcaa tggcgctgga cgcccctcaa cgtcgccagc
    22201 attgaccatc cgcttacctt tagcttcagc gccggtacgc ttgcgcgcag cgacgagctg
    22261 gcgcaatacg gcatcattca cgatccgcac gcctcttcac gactgatgat tgttgaggag
    22321 agcgaggata cgctggcctt agcggagaaa gtgatagcag cgctcaccgc cagcgcagcc
    22381 ggattgattg tggttactcg ccgcgcgtgg cgagtcgagg aaaatgaagc actctctgca
    22441 tcccatcacg cgctatgggc cttgcttcgc gtcgcggcca acgaacagcc ggaacggttg
    22501 cttgccgcca tcgatctcgc cgaaaacacc ccgtgggaaa cgctgcatca agggttgagc
    22561 gcagtctcac tatcacagcg ctggctcgcc gcacggggtg acaccctttg gctcccttca
    22621 ctgacgccca atacgggatg cgccgctgaa ttaccggcaa acgtgtttac cggcgatagc
    22681 cgctggcatc tggtgaccgg agcgtttggc ggattaggcc gccttgccgt gaactggctc
    22741 agagaaaaag gggcgcgacg catcgccctg ctggcaccgc gcgtggatga gtcatggcta
    22801 cgcgacgtgg agggcgggca gacgcgcgtc tgccgttgtg atgtgggcga tgccgggcaa
    22861 ctggccacgg ttcttgacga tctggcggcc aacggcggca ttgccggagc gattcatgcc
    22921 gctggcgtat tggctgacgc gcccttgcag gagcttgatg accaccagct ggctgccgtt
    22981 ttcgcggtaa aagcgcaggc ggcaagccaa ctgttgcaaa ccctgcgcaa ccacgacgga
    23041 cgctatctta ttctctactc ttccgctgcc gccaccctcg gcgcgccggg tcagagcgcc
    23101 catgcgctgg cctgcggcta cctggacggg ctggcccagc agttttccac ccttgatgcg
    23161 ccgaaaacgc tctctgtcgc ctggggcgca tggggagaaa gcggtcgggc ggccacgccg
    23221 gaaatgctgg cgacgctcgc cagccgaggt atgggcgcgt taagcgatgc cgaaggctgc
    23281 tggcacctgg aacaggcggt gatgcgcggc gccccgtggc gactggcgat gcgcgttttt
    23341 accgacaaaa tgcccccgtt acaacaggct ctgtttaaca tcagcgccac agaaaaagcc
    23401 gcaacgccgg tcattcctcc tgctgatgac aacgccttta acggcagcct gagcgatgaa
    23461 acagcggtga tggcatggct gaaaaagcgg attgcggttc agctaaggct gagcgatccg
    23521 gcgtcactgc atccaaacca ggatctgttg caactcggca tggactcgct gctcttcctt
    23581 gaactcagta gcgatattca gcactacctg ggtgtacgca tcaatgcgga acgggcgtgg
    23641 caggatctgt ctcctcatgg actcacgcag cttatctgtt ctaagccaga ggcgacgcct
    23701 gccgcttcgc agccggaagt attgcggcac gacgccgacg agcgttatgc gcccttccct
    23761 ttgacgccca ttcagcacgc ctactggctg gggcgaaccc acctcattgg ctatggcggc
    23821 gtcgcctgtc acgtcctgtt tgagtgggat aaacgccacg atgagttcga tctcgccata
    23881 ctggagaaag catggaacca gctcatcgca cgccacgata tgttgcgtat ggtggttgat
    23941 gccgacgggc agcagcgaat cctggcgaca acgccggagt atcacatccc gcgtgacgat
    24001 ctgcgcgcgc tttccccgga agaacagcgc atcgcactgg aaaaacggcg gcatgaactg
    24061 agctatcgcg ttttgcctgc cgaccagtgg cctctttttg agctggtggt cagcgaaatc
    24121 gacgattgcc attaccgtct gcatatgaac ctcgaccttt tgcagtttga tgtgcagagt
    24181 tttaaagtca tgatggacga cctggcgcag gtctggcgcg gtgaaacgct ggcgccgctc
    24241 gctattacct tccgtgatta tgtgatggct gaacaggcgc gccgacagac atcggcatgg
    24301 cacgatgcct gggattactg gcaggaaaaa ctgccgcaac tgcccttagc gccagagctg
    24361 ccggtggttg agacgccccc ggaaacgcca cacttcacca ccttcaaatc gacgatcggc
    24421 aagacagaat ggcaggccgt gaaacagcgc tggcagcagc aaggcgtcac accgtctgcc
    24481 gcgctgctca cgctgtttgc cgccaccctt gagcgctgga gccgtaccac aacatttacg
    24541 ctgaacctga cgttcttcaa tcgccagccg atccatccgc aaatcaacca gttgattggt
    24601 gattttacct ccgtcacgct ggttgatttt aacttctcag cgccggtgac gttgcaagag
    24661 cagatgcaac agacccaaca gcgcctctgg caaaacatgg cgcacagtga aatgaacggt
    24721 gttgaggtga tccgtgagct gggccgcctg cgcggatcac aacgtcaacc gctgatgccg
    24781 gtagtgttta ccagtatgct ggggatgacg ctggaaggca tgactatcga tcaggcgatg
    24841 agccatctgt tcggcgaacc ctgctatgta ttcacgcaaa cgccgcaggt ctggctggat
    24901 catcaggtca tggagagcga cggcgagttg atgtttagct ggtactgcat ggacaacgtg
    24961 ctggaacccg gcgctgccga ggcgatgttt aatgactatt gcgccatcct gcaagccgtc
    25021 atcgccgccc ctgaaagcct gaagactctc gccagcggca tcgccaggca cattccccgc
    25081 cgacgctggc cgctgaacgc gcaggcggac tacgacctgc gggatattga gcaggcgacg
    25141 ctcgaatacc ccggcatccg gcaggccaga gcggaaataa ccgaacaggg cgcgttgacg
    25201 ctggatatcg tgatggccga cgatccttcg ccatcagcgg cgatgcctga tgagcacgaa
    25261 cttacccaac tggcgctgcc gttgcctgag caggcgcagc ttgatgagct ggaggcgacc
    25321 tggcgctggc tggaggcgcg tgcgctacag gggatcgcgg ctacgctaaa tcgtcacggc
    25381 ctgtttacca cgccggagat cgcccatcgc tttagcgcag tagtacaggc gctgtccgcg
    25441 caagcgtctc accagcgtct gctgcgccag tggctacagt gtctgacgga aagagagtgg
    25501 ttaatccgcg aaggtgaaag ctggcgctgc cgcattccgc tcagcgagat tcctgagcct
    25561 caggaagcgt gcccgcaaag ccaatggagc caggcgctgg cgcagtatct ggaaacctgc
    25621 atcgcccggc acgacgccct cttctccggg cagtgttctc cgctggaatt gctgttcaac
    25681 gagcagcatc gcgttaccga cgcgctgtat cgcgacaacc ccgccagcgc ctgtctgaat
    25741 cgctataccg cgcagattgc cgccttgtgc agcgcagaac ggattctgga ggttggcgcc
    25801 ggaaccgcag ccactaccgc gccggtgctg aaggccacgc ggaacacgcg gcagtcgtac
    25861 cacttcacgg acgtctccgc gcagttcctc aatgacgcca gagcccgttt ccatgatgaa
    25921 tcgcaggtgt cttatgcctt gttcgacatc aaccagccgc tggatttcac cgcccacccg
    25981 gaggcgggtt acgacctgat cgttgccgtc aatgtgctcc acgacgccag ccatgtcgtc
    26041 cagacgttgc gcagattaaa actgttgctg aaagccggcg gacgtttgct gatcgttgaa
    26101 gcgacggagc gaaacagcgt attccagctg gcgagcgtgg gctttattga gggattaagc
    26161 ggataccgcg atttccgccg ccgggatgag aaaccgatgc tcacccgctc cgcatggcag
    26221 gaggttctcg ttcaggccgg gtttgcaaac gagctggcgt ggcccgcgca ggaatcgtcg
    26281 ccgctgcgcc agcatctgct ggtagcgcgt tcgcctggcg taaatcgccc ggataaaaaa
    26341 gccgtgagcc gctatttaca gcagcgcttt ggcaccggtc tgcccatttt acagatccgg
    26401 caaagagaag cgttatttac gccgctgcat gccccgtctg atgcgccgac tgagccagcc
    26461 aaacccacgc cagttgccgg ggggaatccg gcactggaaa aacaggtggc tgaactctgg
    26521 caatcgctgc tgtctcgccc cgtggcaagg catcacgact ttttcgaact gggcggcgac
    26581 agcctgatgg cgacaaggat ggtcgcgcag ctaaaccgga gagggattgc cagggctaac
    26641 cttcaggatc tgttcagcca ttcgacgctg agcgacttct gcgcccatct acaggcggct
    26701 acgtcaggag aggacaaccc gatacccctt tgccagggcg acggtgagga aaccctgttt
    26761 gtcttccacg cttcagacgg cgatatcagc gcctggctgc cgctcgctag cgcgttgaac
    26821 aggcgcgttt tcggcctgca agcaaaatcg ccgcagcgct ttgccacgct cgaccagatg
    26881 atcgatgagt atgtcgggtg catccgtcgt cagcagcctc acggccctta tgtgctggcg
    26941 ggttggtcgt atggcgcgtt tcttgcggcg ggcgccgcac aacgcctgta cgccaaaggc
    27001 gagcaggttc ggatggtgtt aatcgatccc gtgtgccgac aggatttctg ttgcgaaaac
    27061 cgggcggccc tgctgcgcct gttagccgaa ggacaaacgc ctctggcact gcccgaacat
    27121 ttcgaccagc agacgcccga cagccagctt gccgacttta tcagcctcgc taaaacggcc
    27181 ggtatggtgt cgcaaaacct gacgctgcaa gcggcagaaa cgtggctcga caacatcgcg
    27241 catctgctgc gtttactgac tgagcatacg ccgggcgaaa gcgttccggt cccctgtctc
    27301 atggtgtatg ccgccgggag acccgcgcac tggacgccag cagaaaccga gtggcagggc
    27361 tggataaaca acgccgacga cgctgtgatt gaagccagcc actggcaaat catgatggaa
    27421 gccccccacg ttcaggcttg tgcgcaacac attacgcgct ggctttgcgc aacctcaacg
    27481 caaccggaga acacgttatg atgccgtccg cctccccaaa acaacgcgta ctgattgtgg
    27541 gcgccaaatt tggcgaaatg tacctgaatg cctttatgca gcccccggag gggctggaac
    27601 tggtcggcct gctggcgcag ggaagcgccc gttcaagaga gctggctcat gcgtttggca
    27661 ttccgctgta tacctcgccg gaacagataa ccaggatgcc ggatatcgcc tgtattgtcg
    27721 tgcgttcgac cgtcgccgga ggaaccggta cgcagcttgc cagacacttt ctgacgcgcg
    27781 gcgtacacgt cattcaggag catcccctcc acccggatga catcagttcc ttacaaacgc
    27841 tggcgcagga acagggctgc tgctattggg taaacacgtt ttatccgcat acgcgcgcgg
    27901 gacgcacatg gcttcgcgat gcgcagcagc tgcgtcgctg tctggctaag acgccgcagg
    27961 tggtccacgc caccaccagc cgacagttgc tctactccac tctggatttg ttgttgctgg
    28021 ctctgggcgt tgatgccgcc gccgtggagt gcgacgtggt tggcagcttt agcgattttc
    28081 actgtctgag actcttctgg ccggagggag aagcctgcct gctgcttcag cgctatctcg
    28141 atcctgacga tccagatatg catagcctta tcatgcaccg cctgctgctg ggctggccgg
    28201 aaggtcatct ttcgctggag gcgagctacg gccccgtcat ctggtcatcc agcctgtttg
    28261 tcgcagacca tcaggagaac gcccacagcc tctaccgcag accggagatc ctgcgcgatc
    28321 tgccgggtct gacgcgcagc gcggcgcccc tgagctggcg cgactgctgc gaaaccgtcg
    28381 ggccggaggg cgtcagctgg ttgctacacc agttgcgcag ccatctggcg ggcgaacatc
    28441 caccagcggc ctgccaaagc gtacatcaga tcgcgttatc acgtttatgg cagcagattt
    28501 tacgtaagac cggcaatgcg gagatcagac gcctgacgcc gccgcaccac gaccggttag
    28561 ccggtttcta caacgatgat gataaggagg cgctgtgacg caatctgcaa tgtgcatccc
    28621 gctgtggccc gcccggaacg gcaatactgc gcatctggtc atgtgccctt tcgctggcgg
    28681 cagcagtagc gcgtttcgcc actggcaagc tgagcaactg gctgattgcg cgctttctct
    28741 ggtgacctgg ccggggcgcg atcgccttcg ccatctggaa ccgctcagaa acattacaca
    28801 actggcggca ctgctggcga acgagctgga agcatccgta tcgcctgaca cgccgctttt
    28861 actcgccggg cacagcatgg gggcgcaggt ggcgtttgaa acctgccgac ttctggagca
    28921 acgggggctt gcgccacaag gactgattat ttccgggtgc catgccccgc atctgcattc
    28981 tgaacgccag ctcagccatc gcgatgatgc cgactttatc gctgagctga tagacattgg
    29041 cggatgttct cctgaactgc gggaaaacca ggaattaatg tcgctgtttc ttcctcttct
    29101 gcgcgctgat ttttacgcca ccgagagcta tcactacgac tcgcccgacg tctgtccgcc
    29161 gctgcgcacg cctgcgctgt tattgtgcgg cagccacgat cgcgaagcct cctggcagca
    29221 ggtcgatgcc tggcgtcagt ggctgagcca cgttacaggc ccggtggtga ttgacggcga
    29281 tcatttctat cccattcaac aagcccggtc cttttttacg cagattgtcc gccattttcc
    29341 ccacgcattt tctgcaatga ccgcgtggca aaaacagccc agtacttcag aaaggtgacg
    29401 catgaattct tcctttgaat ctctgattga acagtatccc ttacccattg ccgaacagtt
    29461 gcgccactgg gcggcccgtt atgcctcgcg aattgccgtc gttgatgcaa aggggtcgtt
    29521 aacctacagc gcgcttgatg cacaagttga cgaacttgcc gcaggtctgt catcactggg
    29581 tttgcgttcg ggggagcatg taattgtgca gcttcccaac gacaacgcgt ttgttaccct
    29641 gctgttcgcc ttgttaagac tgggcgttat ccccgtgctg gcgatgccct cgcaacgggc
    29701 tctggatatc gacgcgctga ttgagctggc gcaacccgtc gcttacgtta ttcacgggga
    29761 aaacctcgca gagctggccc gacagatggc gcacaaacac gcctgcttgc gtcatgttct
    29821 ggtcgctgga gagaccgtga gcgacgattt tacgccgctc ttctcccttc acggtgagcg
    29881 acaggcatgg ccgcagcctg atgtttccgc caccgcgttg ttgttgctct caggcggcac
    29941 aaccggcacg cccaaactca tcccgcgccg acatgccgac tatagctata acttcagcgc
    30001 ttctgctgaa ctgtgcggca tcagccaaca gagcgtgtat ctcgccgtcc tcccggtggc
    30061 gcataacttt ccgctggcct gccccggtat tctgggaacg cttgcctgcg gcggaaaagt
    30121 ggtgctgacc gacagcgcca gctgtgatga ggtgatgcct ttaatcgcgc aggaaagagt
    30181 gactcacgtc gccctggttc cggcgctggc gcaattatgg gtgcaggcca gggagtggga
    30241 agacagcgac ctttcgtcgc tgcgcgtcat tcaggcaggc ggcgcccggc tcgacccgac
    30301 gcttgctgag caggttatcg ccacctttga ctgtaccctg caacaggttt tcggtatggc
    30361 ggaaggcctg ctctgtttta cccggctgga cgatccgcat gccaccattc tccacagcca
    30421 ggggcgcccg ttgtcccctc tggatgaaat ccgcatcgtt gatcaagacg agaacgacgt
    30481 cgcgccgggc gaaaccgggc aattgttaac gcgcggccct tataccattt cgggctatta
    30541 ccgcgcccct gcccacaacg cgcaggcctt taccgcgcaa gggttttacc gcacaggcga
    30601 caatgtcagg ctggatgagg tggggaacct gcacgttgag ggacgcataa aagagcagat
    30661 caaccgcgcc ggagaaaaaa tagccgcggc tgaagtggaa tcggcactgc tgcgtttagc
    30721 ggaagtgcaa gattgcgcgg tggtcgccgc gccggacacg ctgcttggcg agcggatttg
    30781 cgcgtttatc atcgcgcagc aggtgccaac tgactatcag cagttgcgtc aacaactgac
    30841 ccgtatgggg ctcagcgcgt ggaaaattcc tgaccaaatc gagtttctgg accactggcc
    30901 gctcaccgcc gtcggcaaga tagacaaaaa acgcctgacg gctctcgccg tcgaccgtta
    30961 tcgccattct gcccaataag cgcaaaccga cccgaaacag gttgaaataa acccgtttcg
    31021 ggtagcacca ctattagaaa tagttatcat tttcaattca ccattgtcgg tatttttggc
    31081 gtttcgccgt cttacaggga ctcacaacaa tgaaaatgac acggctttat cctctggcct
    31141 tggggggatt attgctcccc gccattgcta atgcccagac ttcacagcaa gacgaaagca
    31201 cgctggtggt taccgccagt aaacaatctt cccgctcggc atcagccaac aacgtctcat
    31261 ctactgttgt cagcgcgccg gaattaagcg acgccggcgt caccgccagc gacaaactcc
    31321 ccagagtctt gcccgggctc aatattgaaa atagcggcaa catgcttttt tcgacgatct
    31381 cgctacgcgg cgtctcttca gcgcaggact tctataaccc cgccgtcacc ctgtatgtcg
    31441 atggcgtccc tcagctttcc accaacacca tccaggcgct taccgatgtg caaagcgtgg
    31501 agttgctgcg aggcccacag ggaacgttat atggcaaaag cgctcagggc gggatcatca
    31561 acatcgtcac ccagcagccg gacagcacgc cgcgcggcta tattgaaggc ggcgtcagta
    31621 gccgcgacag ttatcgaagt aagttcaacc tgagcggccc cattcaggat ggcctgctgt
    31681 acggcagcgt caccctgtta cgccaagttg atgacggcga catgattaac cccgcgacgg
    31741 gaagcgatga cttaggcggc acccgcgcca gcatagggaa tgtgaaactg cgtctggcgc
    31801 cggacgatca gccctgggaa atgggctttg ccgcctcacg cgaatgtacc cgcgccaccc
    31861 aggacgccta tgtgggatgg aatgatatta agggccgtaa gctgtcgatc agcgatggtt
    31921 caccagaccc gtacatgcgg cgctgcactg acagccagac cctgagtggg aaatacacca
    31981 ccgatgactg ggttttcaac ctgatcagcg cctggcagca gcagcattat tcgcgcacct
    32041 tcccttccgg ttcgttaatc gtcaatatgc ctcagcgctg gaatcaggat gtgcaggagc
    32101 tgcgcgctgc aaccctgggc gatgcgcgta ccgttgatat ggtgtttggg ctgtaccggc
    32161 agaacacccg cgagaagtta aattcagcct acgacatgcc gacaatgcct tatttaagca
    32221 gtaccggcta taccaccgct gaaacgctgg ccgcatacag tgacctgacc tggcatttaa
    32281 ccgatcgttt tgatatcggc ggcggcgtgc gcttctcgca tgataaatcc agtacacaat
    32341 atcacggcag catgctcggc aacccgtttg gcgaccaggg taagagcaat gacgatcagg
    32401 tgctcgggca gctatccgca ggctatatgc tgaccgatga ctggagagtg tatacccgtg
    32461 tagcccaggg atataaacct tccgggtaca acatcgtgcc tactgcgggt cttgatgcca
    32521 aaccgttcgt cgccgagaaa tccatcaact atgaacttgg cacccgctac gaaaccgctg
    32581 acgtcacgct gcaagccgcg acgttttata cccacaccaa agacatgcag ctttactctg
    32641 gcccggtcgg gatgcagaca ttaagcaatg cgggtaaagc cgacgccacc ggcgttgagc
    32701 ttgaagcgaa gtggcggttt gcgccaggct ggtcatggga tatcaatggc aacgtgatcc
    32761 gttccgaatt caccaatgac agtgagttgt atcacggtaa ccgggtgccg ttcgtaccac
    32821 gttatggcgc gggaagcagc gtgaacggcg tgattgatac gcgctatggc gcactgatgc
    32881 cccgactggc ggttaatctg gtcgggccgc attatttcga tggcgacaac cagttgcggc
    32941 aaggcaccta tgccaccctg gacagcagcc tgggctggca ggcgactgaa cggatgaaca
    33001 tttccgtcta tgtcgataac ctgttcgacc gtcgttaccg tacctatggc tacatgaacg
    33061 gcagcagcgc cgtcgcgcag gtcaatatgg gtcgcaccgt cggtatcaat acgcgaattg
    33121 atttcttctg attattgtaa aagggatacc gaaaaggtat cccttttaca ccactagtta
    33181 aaaccagtaa ctcagcagag tcgcaaaaat attaatccat
//
LOCUS       DAFGPF010000051        32691 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFGPF010000051 DAFGPF010000000
VERSION     DAFGPF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32691
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.051"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(27..1706)
                     /gene="bcsG"
                     /locus_tag="LSX49_002610"
     CDS             complement(27..1706)
                     /gene="bcsG"
                     /locus_tag="LSX49_002610"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HBL7169007.1"
                     /translation="MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFAAFLLMPIPHYSLHRLRHWIALPIGFALFWHDTWLPGPESIMSQGSQVAGFS
                     TDYLIDLVTRFINWQMIGAIFVLFVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFS
                     LWPAGQPTTTVTTTGGNAAATVAATGGAPIVGDMPAQTAPPTTANLNAWLNNFYNAEA
                     KRKSIFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATS
                     YSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLK
                     EVRENGGMQSELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNT
                     LPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIDQPSSFLAISDLVVRVLDGK
                     IFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ"
     gene            complement(1703..1894)
                     /gene="bcsF"
                     /locus_tag="LSX49_002611"
     CDS             complement(1703..1894)
                     /gene="bcsF"
                     /locus_tag="LSX49_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HBL7169008.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            complement(1891..3462)
                     /gene="bcsE"
                     /locus_tag="LSX49_002612"
     CDS             complement(1891..3462)
                     /gene="bcsE"
                     /locus_tag="LSX49_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HBL7169009.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKITLFSMLNHEKGLYYLARDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINSGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGCWTLVQHQEAE
                     IQPRSDEKRILSNVAVLEGAPPLSEHWQLFNNNEVLFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLAQSSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            3735..3923
                     /locus_tag="LSX49_002613"
     CDS             3735..3923
                     /locus_tag="LSX49_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HBL7169010.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDILALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            3935..4687
                     /gene="bcsQ"
                     /locus_tag="LSX49_002614"
     CDS             3935..4687
                     /gene="bcsQ"
                     /locus_tag="LSX49_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HBL7169011.1"
                     /translation="MAVLGLQGVRGGVGTTTITAALAWSLQMLGENVLVVDASPDNLL
                     RLSFNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRL
                     SDICSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQ
                     ALPDGAHILINDFRIGSQVQDDIYQLWLQSQRRLLPMLIHRDEAMAECLAAKQPVGEY
                     RSDALAAEEILTLANWCLLNYSGLKTPVGSAS"
     gene            4684..7302
                     /gene="bcsA"
                     /locus_tag="LSX49_002615"
     CDS             4684..7302
                     /gene="bcsA"
                     /locus_tag="LSX49_002615"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HBL7169012.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGASRKETPKPR
                     RRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGTRRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLFHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYIYGPPTEMLTVVVSMVWVFYNLIIL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPAQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            7313..9652
                     /gene="bcsB"
                     /locus_tag="LSX49_002616"
     CDS             7313..9652
                     /gene="bcsB"
                     /locus_tag="LSX49_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBL7169013.1"
                     /translation="MKRKIFWICAVALGMSAFPSFMTQATPATQPLINAEPAVAAQAE
                     QNPQVGQVMPGVQGADAPVVAQNGPSRDVKLTFAQIAPPPGSMVLRGINPNGSIEFGM
                     RSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
                     PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPV
                     PFFDPRDNRTNTLPMVFAGAPDVELQQASAIVASWFGSRSGWRGQNFPVLYNQLPDRN
                     AIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKGIAQ
                     GNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAI
                     NVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEAN
                     RLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNPMPGGSVDNCITFQPVQN
                     HVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKTPNEAQMET
                     LLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIVGGIPDKLKDDKQIDLLVQAT
                     ESWVKTPMRQTPFPGIVPDESDRAAETQSTLTSSGAMAAVIGFQSPYNDQRSVIALLA
                     DSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHLPWFERLWYAL
                     ANHPILLAVLAAISVILLAWVLWRLLRIISRRRLNPDNE"
     gene            9659..10765
                     /gene="bcsZ"
                     /locus_tag="LSX49_002617"
     CDS             9659..10765
                     /gene="bcsZ"
                     /locus_tag="LSX49_002617"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
                     /protein_id="HBL7169014.1"
                     /translation="MNVLRSGLVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVID
                     PSDARKITTSEGQSYGMFFALAANDRAAFDNLLDWTQNNLAQGSLKENLPAWLWGKKE
                     NSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
                     SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFS
                     PDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTE
                     KNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNY
                     VLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH"
     gene            10747..14220
                     /gene="bcsC"
                     /locus_tag="LSX49_002618"
     CDS             10747..14220
                     /gene="bcsC"
                     /locus_tag="LSX49_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
                     /protein_id="HBL7169015.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVIAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADTPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVQALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HNSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAYIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKPNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQE
                     LVNRLQNDQVLETANRLRENGKEAEAEALLRQQPPSSRIDLTLADWAQQRRDYTAARA
                     AYQNVLTREPTNADAILGLTEVDIAAGDKAAARSQLAKLPATDNASLNTQRRVALAQA
                     QLGDTAAAQQTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPMQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            14302..16290
                     /gene="hmsP"
                     /locus_tag="LSX49_002619"
     CDS             14302..16290
                     /gene="hmsP"
                     /locus_tag="LSX49_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HBL7169016.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPPQDLVGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPEDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            16473..17759
                     /gene="dctA"
                     /locus_tag="LSX49_002620"
     CDS             16473..17759
                     /gene="dctA"
                     /locus_tag="LSX49_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HBL7169017.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            17979..19475
                     /locus_tag="LSX49_002621"
     CDS             17979..19475
                     /locus_tag="LSX49_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL7169018.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLDAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAAWDQIMAPSTAAAATSVATDDVHPEVTDIPPAQ"
     gene            complement(19571..20500)
                     /gene="kdgK"
                     /locus_tag="LSX49_002622"
     CDS             complement(19571..20500)
                     /gene="kdgK"
                     /locus_tag="LSX49_002622"
                     /EC_number="2.7.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HBL7169019.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWRGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSATICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAEDAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            20732..21499
                     /gene="pdeH"
                     /locus_tag="LSX49_002623"
     CDS             20732..21499
                     /gene="pdeH"
                     /locus_tag="LSX49_002623"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HBL7169020.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFVEHGLLA
                     SVNIDGPTLIALRQQPKILRQIEELPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            21569..23629
                     /locus_tag="LSX49_002624"
     CDS             21569..23629
                     /locus_tag="LSX49_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312431.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HBL7169021.1"
                     /translation="MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLEKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLSFSEVTGSKGKADKEKVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGG
                     VDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGD
                     SDIHGSLIYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKS
                     VQPAGKVLPYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQP
                     LKFGIAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAE
                     LRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNC
                     AAANLDIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILS
                     QMKK"
     gene            complement(23808..25130)
                     /locus_tag="LSX49_002625"
     CDS             complement(23808..25130)
                     /locus_tag="LSX49_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HBL7169022.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFTPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVSSI
                     LGASVAPYIAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(25523..26536)
                     /gene="yhjD"
                     /locus_tag="LSX49_002626"
     CDS             complement(25523..26536)
                     /gene="yhjD"
                     /locus_tag="LSX49_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HBL7169023.1"
                     /translation="MTQENEIKRPTQDLEHEPIKQLDNSEKGGKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGVAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQP"
     gene            complement(26584..27483)
                     /locus_tag="LSX49_002627"
     CDS             complement(26584..27483)
                     /locus_tag="LSX49_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417978.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7169024.1"
                     /translation="MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQL
                     GTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPSGI
                     AKSLLLPRLSEFLYLHPGIELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGK
                     LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGS
                     MLTVNSSENYLAAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQR
                     RELSRRVNLFMQWLAGVMKEYLD"
     gene            28003..28605
                     /locus_tag="LSX49_002628"
     CDS             28003..28605
                     /locus_tag="LSX49_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL7169025.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQHRIPGVSIQGASQADELWQKLES
                     YPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLITATDCNKRWLQEVIHFNVLAIVP
                     RDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
                     EIGRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS"
     gene            complement(28656..30305)
                     /locus_tag="LSX49_002629"
     CDS             complement(28656..30305)
                     /locus_tag="LSX49_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HBL7169026.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARNWLKTVNQFYLEQHKLI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            30710..32107
                     /gene="ccp"
                     /locus_tag="LSX49_002630"
     CDS             30710..32107
                     /gene="ccp"
                     /locus_tag="LSX49_002630"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HBL7169027.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LANKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKAQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYMPYMQDKQ"
     gene            32318..>32691
                     /locus_tag="LSX49_002631"
     CDS             32318..>32691
                     /locus_tag="LSX49_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBL7169028.1"
                     /translation="MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIG"
BASE COUNT         7864 a         8162 c         8903 g         7762 t
ORIGIN      
        1 gggaaactct gcggcctttt tcgttcttac tgcgggtaag gcacccagtc gccgccgttc
       61 aggcgaacgt acggtttatc ctggtattga ataactactg catttgagtt ctcggagacc
      121 ggtgctgttt gtggtaaccc actggtgagt tttttccagt caacattgtc ttcggtgaaa
      181 atcttgccat caagaacgcg aaccaccaga tcggagatag ccaggaagct gctcggttgg
      241 tcgatgacaa tcggagcccc ctgatgtggt gccttcatgc cgaagaattt caccccaacg
      301 gggacgtctg tgatagacgg gctagggata tcacgtagac cagatacctg cattctgtcg
      361 cccttcagcg cgccgccgtg ttccggcacc acgaccacca tcactttacg acccgatttc
      421 tccagttcag taaagaaggc gtccagttca tcaaagaatt tttgcgcccg cgctttgtaa
      481 tccgctgttt tgctgacgcc cggataatgg ttgccgtcat gcagtggaag cgtgttgtag
      541 aacgtggcac tacggctgtt tttatctttt tcggtaacgt ccagccaacg gttaagcacg
      601 gcggtatcgt cataaaccgg cgaaccatca aagcccagca aaataaccgg cagatttgtt
      661 tgatccatca attcgctctg catgccgcca ttttcgcgaa cttccttcaa aaaaccaccg
      721 aactggccgt tatgtcccat catcaggtgc tgggtaaagc ccagtttcga caggttatca
      781 aacagatagc agtcgttatt tgccggttga tacagattag tgtgcgaagt ctgcccgcag
      841 ctggcgcgca gtaaacggat cgccgccggg ccactgtagg aggtggcgga gttaaagttc
      901 ttgaactcaa tatcgaaatg cgaccacagt ggatgcgaca tcaatccggc ggcttcaata
      961 tccgaccagg aaagcgaaca gatattaatc accagtagtt caaatggctg agcatcagcg
     1021 ggcagcgaag acgggaagat cgatttacgt ttcgcctccg cgttatagaa attattcagc
     1081 caggcgttaa ggtttgctgt tgttggcggt gcagtttgtg cgggcatatc acccactatc
     1141 ggtgcgccac ccgtcgccgc aacggttgcc gctgcgttac cacccgtcgt tgttacagtg
     1201 gtcgttggtt gaccggctgg ccacaaggag aaacttggtc ccgccagggt aagtacgttc
     1261 agccatagca gaatggcaac cacaaaaacg gtaatgcgaa tccattgtga caggaataac
     1321 caggccacga ataaaacaaa aatggcccca atcatctgcc agttaataaa gcgtgtgaca
     1381 agatcgatta aataatcggt actgaacccc gccacctgcg aaccctggct cattatgctt
     1441 tccggaccag gcaaccaggt gtcatgccag aacaaagcaa agccgatcgg cagggcaatc
     1501 cagtggcgca agcgatgcag gctatagtgc ggaatgggca tcagtagaaa cgcggcaaac
     1561 accaaattga ggagcggatg gaagttaaga tatcccgccc acaacaggcc gaacttaacc
     1621 agaaaataga agttccagcc ggaaaggccg cgccagtatt gccagaggga agaaggcatg
     1681 gcggtatttt gcgtaaattg agtcattttt tggttgccct ggctttttcc gtgcggcgta
     1741 acgtcccggc cggtttaaca taacgaggtt tagcaaagaa caaacgtaag gtgtcgcgaa
     1801 tgcgtcgcaa agagtgccgc gccagatagc ccagcgggaa aaatatcagt gcgcaaacga
     1861 caataatttc aatgatatcg ctgatggtca tcatgatgag cgctccacag catcatctaa
     1921 cagtcgcatt ggttctggta ttcgtcgcca gtggcgacca tcatgctcgg cattgatgac
     1981 cggtttagaa ctttgcgcta aaggcagcgg catgccccat tgttctgggg caagcaggcg
     2041 catctgcacc agctcggcac tgatttgatc atcttcaaac cagaccattc ggtttgagaa
     2101 aatgtcgcca gtaggcaatg ggaaaatatg attcaacgcg gtatccagat cgttaatccg
     2161 acagaatgag agaaacagca ccagccgatt accgccaatg gtcatgatat cgccggtacg
     2221 gttagggcga catagcgtca gggcttgctc aacgcggata cccggtaccg gacgtagggc
     2281 aaccagaacg cctttaccgt gggcaggtaa tagagggtta ttcatcatgt tgttgacggc
     2341 attacagaac acatcccact tctggaaacc acgcagtttg agcggctggg tcattgacag
     2401 caaggtagtg atatcttccg gcacatagcg actaaacttc tgcccttgca cgctttcgat
     2461 catcgtcaga cagcgggaga gtggcgcatt ccacgggata accatatttg caccgcaggc
     2521 caataataaa cgttcatcgg tggcgcgcag gctggcggta ttttcccgta cgaggatttt
     2581 catcgcacta ccgcgctggc gacgcagagt atgaatgctg cgggccagtg gctcgatttg
     2641 cgcattttgc tgtaaagaaa agaccaccgt cgccgcctga gcggtacggg cttcattgaa
     2701 caggacttcg ttattgttga acagttgcca gtgttccgat agcggcggcg caccttccag
     2761 tacagcaaca ttactcagaa tgcgtttttc gtcgctgcgt ggttggattt ccgcctcttg
     2821 gtgttgaact aatgtccagc aaccattttg ttgctgaacg ctaagttgct gacgggcgct
     2881 gacccctttt tcgttgcacc agaaagcaat atccagcaaa tgttggtcgc cctgaaaacg
     2941 caaactggca agaccaaaaa gtgaccgata ttcctcaagt aacaatgaaa attgtttatc
     3001 gttattattt ccggaattaa ttaccaaaag cgaacaatgg tttagccggc tccatttatt
     3061 cattttatcc aaccatgagc gaagccgctc ggcaggaatg ttttgccatg cattatttgc
     3121 gcaaacaaga ataaaaaggt aattatgggg atcaatagaa cactgcaaat cacgggccaa
     3181 atagtataga cctttttcat gatttagcat cgaaaataat gttatttttt ccggcccttg
     3241 agaatcatct aattgaaaga ttttcgctgg atcgctgtcc atgctaatga ccgcgacgtg
     3301 tgcggtttca gcctgggatg caattgtttg attcgccaga ctgatagcat cttcatggcg
     3361 atcgacgtta aaccaccaga cgccgcctgc tggcatatgt cgcagctcat cccataatga
     3421 tgagataccg atagagaata cagggtccac aatgtccctc atgtcaacat tttgtctgat
     3481 tatcagttta ctagcgaaag ctaagaaata aacctaccat tgaaattaaa acttatcaga
     3541 tttagcatgt gaatcaattt agcaggtcac aagacatgtg attttagtct tttcgttttt
     3601 aactttttct gttgcataac ggaaagtcaa aaagtgagca cattcccgtc tcgccgtaaa
     3661 caataaaccg acgaaatgct cacagttaga attgtctcat gaacggtacg gttatttcat
     3721 agggatcaag aaaaatgaat aacaatgaac cagatactct gcctgatccc gcgataggct
     3781 atatcttcca gaatgatatt ttggcgttaa agcaggcatt ttcactgcct gatattgatt
     3841 atgccgatat ttcccaacgc gaacagttgg ccgcggcatt aaaacgctgg ccgttgctgg
     3901 cagagtttgc gcaacaaaag taggggattg gtgaatggcc gtactgggat tgcagggggt
     3961 tcggggaggc gtggggacaa caaccatcac cgccgcatta gcctggtcat tacaaatgtt
     4021 gggagaaaat gtcctggtgg tcgatgccag cccggacaac ttgttgcgcc tgtcatttaa
     4081 cgttgatttt acccaccgtc agggttgggc cagagctatg ctggatggcc aggactggcg
     4141 tgacgccggg ttgcgctata cctcgcagct cgatttgctg ccttttggtc agttatcgat
     4201 tgaagaacaa gaaaatccac agcactggca aacccggctg agcgatattt gctccggctt
     4261 acagcaacta aaagccagcg ggcgttacca gtggatttta attgacttac cgcgtgatgc
     4321 ctcgcagata acccaccagc tgctgagttt gtgcgatcac tcgctggcaa tcgtcaatgt
     4381 ggatgccaac tgccatatcc gactgcatca gcaagcgctg ccggatggtg cacatatttt
     4441 gattaatgac ttccgtattg gcagccaggt tcaggacgat atttaccagc tttggttgca
     4501 aagccagcgc cgattgctgc cgatgctcat tcatcgtgat gaagcgatgg ctgaatgtct
     4561 ggcagctaag caaccagtcg gtgaatatcg cagtgatgcg ctggcggctg aagagatact
     4621 gacgctggcg aactggtgcc tgttgaatta ttccgggctg aaaacgccag tcgggagtgc
     4681 atcatgagta tcctgacccg gtggttgctt atcccgccgg tcaacgcacg gcttattggg
     4741 cgttatcgcg attatcgtcg tcacggcgcg tcggctttca gcgcgacgct cggctgtttc
     4801 tggatgatcc tggcctggat ttttattccg ctggagcacc cgcgctggca gcgtattcgc
     4861 gcagaacata aaaacctgta tccgcatatc aacgcctcgc gtccgcgtcc gctggacccg
     4921 gtccgttatc ttattcaaac atgctggtta ctgatcggtg catcgcgcaa agaaacgccg
     4981 aaaccgcgca ggcgggcatt ttcaggtcta caaaatattc gtggacgtta ccatcaatgg
     5041 atgaatgagc tgcctgagcg cgttagccat aaaacacagc atcttgatga gaaaaaagag
     5101 ctcggtcatt tgagtgccgg gacgcggcgg ttgatcctcg gtatcatcgt caccttctcg
     5161 ctgattctgg cgttaatctg cgttactcag ccgtttaacc cgctagcgca gtttatcttc
     5221 ctgatgctgc tgtggggggt agcgctgatc gtacggcgga tgccggggcg cttctcggcg
     5281 ctgatgctga ttgtgctgtc gctgaccgtt tcttgccgtt atatctggtg gcgttacacc
     5341 tcgacgttaa actgggacga tccggtcagc ctggtgtgcg ggcttattct gctcttcgct
     5401 gaaacgtacg cgtggattgt gctggtgctc ggctatttcc aggtcgtatg gccgctgaat
     5461 cgtcagccgg tgccattgcc gaaagatatg tcgctgtggc cgtcggtgga tatctttgtc
     5521 ccgacttaca acgaagatct caacgtggtg aaaaatacca tttacgcttc gctgggtatc
     5581 gactggccga aagacaagct gaacatctgg atcctcgatg acggcggcag ggaagagttt
     5641 cgccagtttg cgcaaaacgt gggggtgaaa tatatcgccc gtaccactca tgaacatgcg
     5701 aaagcgggca acatcaacaa tgcgctgaaa tatgccaaag gcgagttcgt gtcgatattc
     5761 gactgcgacc acgtaccaac gcgatcgttc ctgcaaatga ccatgggctg gttcctgaaa
     5821 gagaaacagc tggcgatgat gcagacgccg caccacttct tctcgccgga tccgtttgaa
     5881 cgcaacctgg ggcgttttcg taaaacgccg aacgaaggca cgctgtttta tggtctggtg
     5941 caggacggca atgatatgtg ggatgccact ttcttctgcg gttcatgtgc ggtgattcgc
     6001 cgtaagccgc tggatgagat tggcggtatt gctgtcgaaa cggtaaccga agatgcgcac
     6061 acttctctgc gtctgcaccg tcgtggctac acctcagcgt atatgcgtat tccgcaggca
     6121 gcggggctgg cgaccgaaag tctctcggcg catatcggtc agcgtattcg ctgggcgcgc
     6181 gggatggtgc aaatcttccg tctcgataac ccgctcaccg gtaaagggct gaagtttgct
     6241 cagcggctgt gctatgtcaa cgccatgttc cacttcttgt cgggcattcc acgactgatc
     6301 ttcctgactg cgccgctggc gttcctgctg tttcatgcct acatcatcta cgcgccagcg
     6361 ttgatgatcg ccctgttcgt gctaccgcat atgatccatg ccagcctgac taactcgaag
     6421 atccagggca aatatcgcca ctctttctgg agtgaaatct acgaaacggt gctggcgtgg
     6481 tatatcgcac caccgacgct ggtggcgctg attaacccgc acaaaggcaa atttaacgtc
     6541 accgccaaag gtggactggt ggaagaagag tacgtcgact gggtgatctc gcggccctac
     6601 atcttccttg ttctgctcaa cctggtgggc gtagcggttg ggatctggcg ctacatctat
     6661 ggtccgccaa ccgagatgct caccgtggtc gtcagtatgg tgtgggtatt ctacaacctg
     6721 attattctcg gcggcgcagt cgcagtatcg gtagaaagca aacaggtacg ccgatcgcac
     6781 cgcgtggaga tgacgatgcc cgcagcaatt gcccgcgaag atggtcacct cttctcgtgt
     6841 accgttcagg atttctccga cggtggtttg gggatcaaga tcaacggtca ggcgcagatt
     6901 ctggaagggc agaaagtgaa tctgttgctt aaacgcggtc agcaggaata cgtcttcccg
     6961 gctcaggtgg cgcgcgtgat gggtaatgaa gttgggctga aattaatgcc gctcactacc
     7021 cagcaacata tcgattttgt gcagtgtacg tttgcccgtg cggatacatg ggcgctctgg
     7081 caggacagct acccggaaga taagccgctg gaaagtctgc tggatattct gaagctcggc
     7141 ttccgtggct accgccatct ggcggaattt gcgccttctt cggtgaaggg catattccgt
     7201 gtgctgactt ctctggtttc ctgggttgta tcgtttattc cgcgccgccc ggagcggagc
     7261 gaaacggcac aaccatcgga tcaggctttg gctcaacaat gatgataacg cgatgaaaag
     7321 aaaaatattc tggatttgtg cagtggctct ggggatgagt gcgttcccct ctttcatgac
     7381 gcaggcgacg ccagcaacgc aaccactgat caatgctgag ccagctgtag ccgcccaggc
     7441 ggagcaaaat ccgcaggtgg ggcaagtgat gccgggcgtg cagggcgcag atgcgccagt
     7501 cgtggcgcag aacggtcctt cccgtgatgt gaagctgacc tttgcgcaaa ttgcgccgcc
     7561 gccgggcagc atggtgctac gtggcattaa cccgaacggc agcattgagt ttggtatgcg
     7621 cagcgatgaa gtggtgacga aggcgatgct caacctcgaa tacacgccat cgccatcatt
     7681 actgcctgtc cagtcgcagt taaaggttta tctcaatgat gaactgatgg gcgtgctgcc
     7741 agtgaccaaa gaacagttgg gtaaaaaaac gctggcacaa atgcccatta acccgctgtt
     7801 tattactgat ttcaaccgtg tgcggctgga gtttgtcggc cattatcagg acgtgtgcga
     7861 aaacccggcc agcaccacgc tttggctgga tgttgggcgg agcagtggac tggatctgac
     7921 ctatcagacc ctgaatgtga agaatgacct gtcacacttc ccggtgccat tctttgaccc
     7981 gcgtgataac cgcaccaaca ccttgccgat ggtctttgcg ggtgcgccgg atgttgagct
     8041 gcaacaagca tctgccattg tcgcctcgtg gtttggttcg cgttctggct ggcgtgggca
     8101 gaacttcccg gtgctctata accaactgcc ggatcgcaat gccattgtct ttgccaccaa
     8161 tgacaaacgc ccggacttcc tgcgcgatca tccggcggta aaagccccgg tgattgagat
     8221 gattaaccat ccgcagaatc cttacgtcaa actgctggtg gtgtttggtc gtgacgacaa
     8281 agacctgttg caggcagcga aaggtatcgc tcagggtaac attctgttcc gtggtgaaag
     8341 tgtggtagtg aatgaagtga aaccgctgct accgcgtaaa ccgtacgatg cgccgaactg
     8401 ggtgcgtacc gatcgtcctg tcacctttgg tgaactgaaa acctatgaag aacaattaca
     8461 atccagcggt cttgagccag cagcgattaa cgtttcgcta aacctgccgc cggatctcta
     8521 cctgatgcgc agtaccggca ttgatatgga tattaattac cgctacacca tgccgccggt
     8581 gaaagacagt tcgcggatgg atatcagcct gaataaccag ttcctgcaat ccttcaacct
     8641 gagcagcaaa caggaggcga accgcctgct gctgcgtatt ccggtattac aaggtttgct
     8701 ggatggcaaa acggatgtct ctattccggc gctgaaactg ggcgcgacca accagttgcg
     8761 gttcgacttt gagtatatga acccgatgcc gggcggttcg gtggataact gtattacctt
     8821 ccagccggtg cagaatcatg tggtgattgg tgacgactcc accatcgact tctcgaagta
     8881 ttaccacttc atcccgatgc cggatctacg cgcctttgct aacgcgggct tcccgttcag
     8941 ccggatggcg gatttgtcgc aaaccatcac cgtgatgccg aaaacgccaa acgaagcaca
     9001 gatggaaacc ttgctgaata ccgttggctt tatcggtgcg cagacgggct tcccggcgat
     9061 taacctgacg gtgaccgatg atggcagcac cattcagggc aaagatgccg acatcatgat
     9121 cgtcggtggt atcccggaca aactgaaaga cgataagcag atcgacctgt tggtgcaggc
     9181 gaccgaaagc tgggtgaaaa cgccgatgcg ccagaccccg ttccccggta ttgtgccgga
     9241 cgagagcgat cgcgcggcag aaacccagtc aacgctgacc tcttccggtg cgatggcggc
     9301 ggtgattggc ttccagtcgc cgtataacga ccagcgcagc gtgattgcgc tgctggcaga
     9361 tagcccacgc ggttatgaaa tgcttaacga tgcggtgaac gatagcggca aacgcgccac
     9421 catgttcggt tcggtcgcgg tgatccgcga gtccggtatc aacagcctac gtgttggcga
     9481 tgtttattac gtaggtcatc tgccgtggtt cgagcgcttg tggtatgcgc tggcaaacca
     9541 tccgattctg ctggcggtgc tggcggctat cagtgtgata ttgctggcgt gggtactgtg
     9601 gcgtctgctg cgtattatta gtcgtcgtcg tcttaacccg gataacgagt aattgaagat
     9661 gaatgtgttg cgtagtggac tcgtgacgat gctgctgctg gctgccttta gtgttcaggc
     9721 agcctgtacc tggcctgcct gggagcagtt taaaaaggat tacatcagtc aggaagggcg
     9781 cgtcatcgac cccagcgacg cgcgcaaaat caccacctcc gaagggcaaa gttacggcat
     9841 gttctttgcc ctggcggcta acgaccgtgc agctttcgat aatcttctcg actggacgca
     9901 gaacaatctc gctcagggtt ctttaaaaga aaatttgccc gcctggctgt ggggcaagaa
     9961 agagaacagt aagtgggaag tgctggacag caattcggcc tccgatggtg atgtctggat
    10021 ggcctggtcg ttgctggagg cggggcgttt gtggaaagag cagcgttata ccgacatcgg
    10081 cagcgcattg ctaaaacgta tcgcgcggga ggaagtggtg acggtgcctg ggctgggctc
    10141 catgttgtta ccgggcaaag tgggttttgc tgaggataac agctggcgtt ttaaccccag
    10201 ctacctgccg ccgacgctgg cgcagtattt cacccgcttt ggcgcgccgt ggaccacgct
    10261 gcgcgaaacc aatcaacgtt tattgctgga aaccgccccg aaaggctttt cgccagactg
    10321 ggtgcgctat gagaaagaca aaggctggca gctaaaagcc gaaaaaacgt tgatcagcag
    10381 ctacgacgct atccgcgttt acatgtgggt aggcatgatg cctgacagcg atccgcaaaa
    10441 agcgcggatg ctcaaccggt ttaaaccgat ggcgacattc actgagaaaa acggttatcc
    10501 gccggaaaaa gtggatgtgg ctacggggaa agcgcagggt aaaggaccgg tcggtttttc
    10561 tgccgccatg ctgccctttt tacaaaaccg cgatgcgcag gccgttcagc gccagcgcgt
    10621 ggccgataac tttcccggca gcgatgccta ttacaactat gtgctgaccc tgtttggaca
    10681 aggctgggat caacaccgtt tccgcttctc gacaaaaggt gagttattac ctgactgggg
    10741 ccaggaatgc gcaaattcac actaaacata ttcacgcttt ccctcggtct ggccgtcatg
    10801 ccgatggtcg aggcagcacc aaccgctcag caacagttgc tggagcaagt tcggttaggc
    10861 gaagcgaccc atcgtgaaga cctggtgcaa cagtcgttgt atcggctgga acttattgat
    10921 ccgaataacc cggatgtgat tgctgcccgt tttcgttctc tgttacgtca gggcgatatt
    10981 gatggcgcac aaaaacagct cgatcggctg tcgcagttag cgccgagttc aaatgcgtat
    11041 aaatcgtcgc ggactacgat gctgctttcc acgccggatg gtcgtcaggc actgcaacag
    11101 gcaagattgc aggcaactac cggtcatgcg gaagaagctg tggcgagtta caacaaactg
    11161 ttcaacggtg cgccgccgga aggtgacatt gctgtcgagt actggagtac ggtggcgaaa
    11221 attccggctc gccgtggcga agcgattaat cagctaaagc gcattaatgc ggatacgccg
    11281 ggcaacacgg gcctgcaaaa caatctggcg ctattgctgt ttagtagcga tcgccgtgac
    11341 gaaggctttg ccgtcctgga acaaatggcg aaatcgaacg ccgggcgcga aggggcctct
    11401 aaaatctggt acgggcagat taaagacatg cccgtcagcg atgccagcgt gcaggcactg
    11461 aaaaaatatc tctcgatctt tagcgatggc gatagcgtgg ctgctgcgca atcgcaactg
    11521 gcagaacagc aaaaacagct ggccgatcct gctttccgcg ctcgtgcgca aggtttagcg
    11581 gcggtggact ctggcatggc gggtaaagcc attcccgaac tacaacaggc ggtgcgggcg
    11641 aacccgaaag acagtgaggc tctgggggcg ctgggccagg cgtattccca gaaaggtgat
    11701 cgcgccaatg cagtggcgaa tctggaaaaa gccctcgcgc tggatccgca caacagcaat
    11761 aacgacaaat ggaacagtct gctgaaagta aaccgctact ggctggcgat ccagcagggc
    11821 gatgccgcgc tgaaagccaa taatcctgac cgggcagaac ggctgttcca gcaggcacgt
    11881 aatgtcgata acaccgacag ctatgcagtg cttgggctgg gcgatgtggc gatggcgcgc
    11941 aaagattatc ccgccgccga acgctattac cagcagacct tgcgtatgga cagcggcaac
    12001 actaacgccg tgcgcgggct ggcgaatatt taccgccagc agtcgccaga aaaagccgaa
    12061 gcgtatatcg catcgctctc tgccagccag cggcgcagca ttgatgatat cgaacgcagc
    12121 ctgcaaaacg accgtctggc acagcaggca gaggcactgg aaaaccaggg gaaatgggcg
    12181 caggcggcag cacttcagcg gcaacgactg gcgctggacc ccggcagtgt atggattact
    12241 taccgacttt cgcaggatct ctggcaagcc ggacaacgca gccaggccga tacgttaatg
    12301 cgcaatctgg cgcagcagaa gccgaacgac ccggagcagg tttacgctta cgggctgtat
    12361 ctctccggtc acgaccagga cagagcggcg ctggcgcata tcaacagcct gccgcgcgcg
    12421 cagtggaaca gcaatattca ggagctggtt aatcgactgc aaaacgatca ggtgctggaa
    12481 accgctaatc gcctgcgaga aaacggtaaa gaggcagaag cggaagcgct gctgcgccag
    12541 caaccgcctt cctcgcgtat tgacctcacg ctggctgact gggcgcagca gcgacgtgat
    12601 tacaccgccg cccgcgcggc ttatcagaac gttttgacgc gcgagcccac taacgccgat
    12661 gccattcttg gtctgacgga agtggatatt gctgccggtg acaaagcggc ggcacgtagc
    12721 cagctggcga aactgcctgc cactgataac gcctcgctga acacacagcg gcgcgtggcg
    12781 ctggcacagg cgcagcttgg cgataccgca gcggcgcagc agacatttaa taagttgatc
    12841 ccgcaggcaa aatctcagcc accgtcgatg gaaagcgcga tggtactgcg tgatggtgcg
    12901 aagtttgaag cgcaggcggg cgatccaatg caggcgctgg aaacctacaa agacgccatg
    12961 gttgcatccg gtgtgaccac gacgcgtccg caggataacg acacctttac ccggctgacc
    13021 cgtaacgacg agaaagatga ctggctgaaa cgcggcgtgc gcagcgatgc ggcggacctc
    13081 tatcgccagc aggatcttaa cgtcactctc gagcacgatt actggggttc gagcggcacc
    13141 ggtggttact ccgatctgaa agcgcacacc actatgttgc aggtggacgc gccctattct
    13201 gacgggcgga tgttctttcg cagtgatttc gtcaatatga acgtcggcag tttctccact
    13261 aatgccgatg gcaaatggga tgacaactgg ggcacctgta cattacagga ctgtagcggc
    13321 aaccgcagcc agtcggattc cggtgccagc gtggcggtcg gctggcgaaa tgacgtctgg
    13381 agctgggata tcggtaccac gccgatgggc ttcaacgtgg tggatgtggt cggcggcatc
    13441 agttacagcg atgatatcgg gccgctgggt tacaccgtta acgcccaccg tcggcctatc
    13501 tccagttctt tgctggcctt tggtgggcaa aaagactctc cgagcaatac cgggaaaaaa
    13561 tggggcggcg tgcgtgccga cggcgtgggg ctaagtctga gctacgataa aggtgaagca
    13621 aacggcgtct gggcatcgct tagcggtgat cagttaaccg gtaaaaatgt cgaagataac
    13681 tggcgcgtgc gctggatgac gggctattac tataaggtca tcaaccagaa caatcgccgc
    13741 gtcacaatcg gcctgaacaa catgatctgg cattacgaca aagacctgag tggctactca
    13801 ctcggtcagg gcggttacta cagtccgcag gaatacctgt cgtttgccat accggtgatg
    13861 tggcgggagc gcacggaaaa ctggtcgtgg gagctggggg cgtctggctc gtggtcgcat
    13921 tcacgcacca aaaccatgcc gcgttatccg ctgatgaatc tgatcccgac cgactggcag
    13981 gaagaagctg cgcggcaatc caacgatggc ggcagcagtc agggctttgg ctacacggcg
    14041 cgggcattac ttgaacgacg tgttacttcc aactggtttg tcggcacggc aattgatatc
    14101 cagcaggcaa aagattacgc acccagccat ttcctgctct acgtacgtta ttccgccgcc
    14161 ggatggcagg gtgacatgga tttaccaccg cagccgctga taccttacgc cgactggtaa
    14221 gttttcagat agcgcctctc ttaatgccgc tgcgatcggg tatactcggg cggcaatctg
    14281 ggatttccgg ggggagacaa tttgcgcgta agtcgctcgt taacaatcaa gcagatggca
    14341 atggtggcag ccgttgtcct ggtgttcgtt tttatttttt gcaccgtttt gctgttccat
    14401 ctggtccagc agaatcgcta taacacggct acgcaactgg aaagcattgc tcgctctgtc
    14461 cgcgaaccct tatcttctgc cattttgaaa ggcgatattc ccgaagcgga agctattctt
    14521 gccagcatta aaccggcagg cgtggtcagc cgtgccgatg tagtgctgcc caaccagttc
    14581 caggcgctgc gtaaaagttt tattccagag cgtccggtgc cggtaatggt tactcgcctg
    14641 tttgagctac cggtgcaaat ctcgctgggc gtttactcgc tggaacgtcc ggcaaacccg
    14701 cagccaattg cctatctggt gctacaggcg gattccttcc gcatgtataa gttcgtgatg
    14761 agcaccctct caacgttagt gaccatttac ttacttttgt cgttaatatt gactgtggcg
    14821 attagctggt gcattaaccg cctgattttg catccattac gcaatattgc tcgcgaactt
    14881 aacgccatcc caccccagga tcttgttggt caccaactgg cattaccgcg tctgcatcag
    14941 gacgatgaaa tcggtatgtt ggtgcgcagt tacaacctca accagcaatt gctgcagcgc
    15001 cattatgaag aacagaacga aaatgcgatg cgcttcccgg tgtcggattt gccgaacaaa
    15061 gccttgctga tggagatgct ggagcaggtg gtggcgcgta aacaaaccac cgcgctgatg
    15121 atcatcacct gtgaaaccct gcgtgatact gcgggtgtgc tgaaagaggc gcaacgagaa
    15181 attctgctgc tgacgctggt ggaaaaactc aaatcggtac tgtcgccacg catgatcctc
    15241 gcgcagatta gcggttatga ctttgctgtc attgccaacg gtgtacagga accgtggcac
    15301 gctatcacat taggtcagca agtgctcact atcatgagcg agcgcctgcc gattgaacgt
    15361 attcaactcc gtccgcactg tagcattggc gtggcgatgt tctacggcga tctcaccgcc
    15421 gaacagcttt acagtcgcgc tatttctgcg gcatttaccg ctcgccataa aggcaaaaat
    15481 cagattcagt tctttgatcc gcagcagatg gaagccgccc agaagcggtt gacggaagag
    15541 agcgatatcc ttaatgcact ggaaaatcat cagtttgcga tttggttaca gccacaggtc
    15601 gagatgacca gcggtaaact ggtcagtgcg gaagtgttac tgcgtatcca gcaaccggat
    15661 ggcagttggg acctgccgga tggcttaatc gatcgcattg agtgctgtgg gctgatggtt
    15721 accgtcggtc actgggtgct ggaagagtcc tgtcgattgc ttgctgcctg gcaagagcgc
    15781 ggcattatgc tgcccttgtc ggtaaacctc tcagcgctgc aactgatgca tccaaatatg
    15841 gtggcggata tgctggaact gttaacccgc tatcgcattc agccgggaac actgattctg
    15901 gaagtgacag aaagccgacg tattgacgat cctcatgctg cggtggcaat cctccgtccg
    15961 ctgcgcaatg ccggagttcg ggtggcgctg gatgatttcg gcatgggcta cgcagggctg
    16021 cgtcagctgc agcatatgaa atcgttgcca atcgacgtac tgaaaatcga caaaatgttt
    16081 gttgaaggtt tgccggaaga tagcagcatg attgctgcaa ttatcatgct ggcgcagagc
    16141 ctgaacctac aaatgattgc cgaaggcgtg gagactgaag cacaacgcga ctggctggca
    16201 aaagcgggcg ttggtattgc ccagggcttc ctttttgctc gcccactccc tattgaaatc
    16261 ttcgaagaga gttacctgga agaaaaatag ctaccccaaa ctgattacaa aactttaaaa
    16321 agtgctggtt tgtgcgagcc agctcaaact ttttaacctt tttgtttcaa ttatgatcca
    16381 ggtacatttc tgtgatgttg tctgggtgtt attttaaggc cgcaggtacc ccataacctt
    16441 acaagacctg tggttttact aaaggacacc ctatgaaaac ctctctgttt aaaagccttt
    16501 actttcaggt cctgacagcg atagccattg gtattctcct tggccatttc tatcctgaaa
    16561 taggcgagca aatgaaaccg cttggcgacg gcttcgttaa gctcattaag atgatcatcg
    16621 ctcctgtcat cttctgtacc gtcgtaacgg gcattgcggg catggaaagc atgaaggcgg
    16681 tcggtcgtac cggcgcagtc gcactgcttt actttgaaat tgtcagtacc atcgcgctga
    16741 ttattggtct tatcatcgtt aacgtcgtgc agcctggtgc cggaatgaac gtcgatccgg
    16801 caacgcttga tgcgaaagcg gtagcggttt acgccgatca ggcgaaagac cagggcattg
    16861 tcgccttcat tatggatgtc atcccggcga gcgtcattgg cgcatttgct agcggtaaca
    16921 ttctgcaggt actgctgttt gccgtactgt ttggttttgc gctccaccgt ctgggcagca
    16981 aaggccaact gatttttaac gtgatcgaaa gtttctcgca ggtcattttc ggcatcatca
    17041 atatgatcat gcgtctggca cctattggtg cgttcggggc aatggcgttt accatcggta
    17101 aatacggcgt cggcacactg gtgcaactgg gacagctgat tatctgtttc tacatcacct
    17161 gtatcctgtt tgtggtgctg gtattgggtt caatcgctaa agcgactggt ttcagtatct
    17221 tcaaatttat ccgttacatc cgtgaagaac tgctgattgt actggggact tcatcttccg
    17281 agtcggcgct gccgcgtatg ctcgacaaga tggagaaact cggctgccgc aaatcggtgg
    17341 tggggctggt catcccgaca ggctactcgt ttaatcttga tggcacatcg atatacctga
    17401 caatggcggc ggtgtttatc gcccaggcca ctaacagtca gatggatatc gtccaccaaa
    17461 tcacgctgtt aatcgtgttg ctgctttctt ctaaaggggc ggcaggggta acgggtagtg
    17521 gttttatcgt gctggcagcg acgctctctg cggtgggcca tttgccggta gcgggtctgg
    17581 cgctgatcct cggtatcgac cgctttatgt cagaagctcg tgcgctgact aacctggtcg
    17641 gtaacggcgt agcgaccatt gtcgttgcta agtgggtgaa agaactggac cacaaaaaac
    17701 tggacgatgt gctgaataat cgtgcgccgg atggcaaaac gcacgaatta tcctcttaat
    17761 ctcaccactt atgcccgcac tcccttcccc gagtgcgggt gtttgcgcat aattgacccc
    17821 tgtgcctgaa cttaccacct gggtgagttc aggtttattt cacttcttcc gtgacatttt
    17881 catgttcttg cggtctaaca cgaagtgttt ttaacgtcat ttagactgac cgacaacggg
    17941 cagtttttta ttaccaggat agttgatcag gggttcacat gcagggcaca aaaattcgac
    18001 ttttagcggg cggtttgctg atgatggcca ctgctggcta tgtgcaggca gatgcgctcc
    18061 agcctgatcc agcatggcaa caggggacgc tttccaacgg tttacagtgg caagtgctga
    18121 ctacacccca gcgtcccagc gatcgtgttg aaattcgcct gctggttaat accggttcgc
    18181 tcgccgaaag tacacaacag agcggttaca gtcacgccat ccctcgtatt gcgctaacgc
    18241 aaagcggtgg ccttgacgca gcgcaggcgc gttcattgtg gcagcagggg atcgacccta
    18301 aacgcccgat gccgccggta attgtctctt atgacaccac gctgtttaat ctgagtttgc
    18361 ccaataaccg taacgacttg ctgaaagagg cgctctctta tctggcaaat gccactggca
    18421 aactgactat cacgccagaa accatcaacc atgcgttgca aagtcaggac atggtggcaa
    18481 cctggcctgc cgatactaaa gagggctggt ggcgttatcg tctgaaagga tcaaccttgt
    18541 taggtcacga tcctgccgat ccgctgaaac aacccgttga agcggaaaag attaaagatt
    18601 tctatcagaa atggtacacc ccggatgcaa tgacgctgct ggtggtggga aacgtggatg
    18661 cgcgctcggt cgtcgaccaa atcaataaaa cgtttggcga actgaaaggc aaacgtgaaa
    18721 caccggctcc ggtgccgacg ctttctccgc tgcgtgcgga agcggtgagt attatgaccg
    18781 acgcggtgcg tcaggaccgg ttatctatca tgtgggatac gccgtggcag ccgattcgtg
    18841 aatcagccgc actgctgcgc tactggcgtg cggacctggc ccgtgaggcg ctgttctggc
    18901 atgttcagca agcgttaagc gccagtaaca gtaaagacat cggtcttgga tttgactgtc
    18961 gtgtgctgta tctgcgtgcg cagtgtgcca tcaacatcga atcaccaaac gacaagctga
    19021 acagcaacct taatctggtg gcgcgtgaac tggcgaaggt tcgcgataaa ggtctgccgg
    19081 aagaagagtt caatgcgtta gtggcgcaaa agaaactgga gctgcagaag ctgtttgccg
    19141 cctatgcgcg agctgatacc gatattctga tggggcagcg gatgcgttcg ttgcaaaatc
    19201 aggttgtcga tatcgcgccg gagcaatatc agaaactgcg tcaggatttc cttaacagcc
    19261 tgacggtgga gatgttaaat caggatctgc gtcagcagtt gtcgaatgat atggcgttaa
    19321 tactgctgca gccgaaaggc gagccggaat ttaacatgaa agcgttgcag gcggcctggg
    19381 atcaaatcat ggccccatcg actgcggctg ccgccacatc tgtcgccacg gatgacgtac
    19441 atcctgaagt gacggatatt ccacctgcac agtaatgcct gatggtgatg agttagcaca
    19501 accatcaggt atttatggat gagctggata ggggggtaac actctatcca gccttttgca
    19561 tatgctgctt ttacgctggc atcgcttcac gcgggataat cgcgccgcga tactgaataa
    19621 cggtacttgc ggtcaggtgc ccgcgtttcg ctgcgtcttc cgcactgccg cccgtcaaac
    19681 gtaccgccag ataaccggca ctgaaagagt cgccagctgc ggtggtatcg atcacttttt
    19741 ctttcggcag ttttaccgcc ggaacatcca ctaacccttc accagcaatg gacaccaggc
    19801 aagaatccgc cccgcgtttc accaccactt ctttcacgcc cgcgttatgg gtgcgcgcaa
    19861 tgacgtcttc caccggctgt tgaccccaca gcgcgtcttc atcgtccagc gtcaggaagg
    19921 cgatatccgt gcattccagc atttgttggt acacctgctg tgtctcttct ttgctggccc
    19981 acaggcgcgg acgatagtta ttgtcgaaaa tcacttttcc gccgttggcg cggcattcgc
    20041 gcagcaggga aagcagcttt tcgcggctgg tcgggcttaa gatcgccagg ctaatcccgc
    20101 tcaggtagag ataatcgaaa ttcgccagct cttcgcaaat cgtcgcggat tgctcactct
    20161 ccagccagaa tttggcggcg gcttcgttac gccagtagta gaacgtacgt tcgccggtgc
    20221 tgtcggtttc aatgtagtaa aggcccggca gacggttttc catccgttgg gtcagggaag
    20281 tatcaacgtt ctcgccgcgc caggcgtcca gcatctgctg gctaaaactg tccgttccca
    20341 gcgccgttac gtaatgaacg gttaatgccg caggatcgac ctgacgggcg atatagacgg
    20401 aagtgttcag ggtatcgccc ccgaaaccgc gcttaacgtc cgcgcctttc tcggaaagct
    20461 caatcatgca ttcgccaatc acggcaatct ttttggacat agttgtgaac ctgatctgta
    20521 aaaaattagc gttagtttgc gctgtggtgg tttgctggtc aaccatatta aaacagtgtt
    20581 ccattatttt tttgagccag aacgtattcc tgaaagattc cgttgtggag tggggaaatt
    20641 taccccggcc aggcggtaaa gttctgcctt tgcgcgccga taatctttgt cgagtccggg
    20701 cagcatcact tttaaacaca ggacatcttt gatgataagg caggttatcc agcgaataag
    20761 caaccctgaa gcaagcatcg agagcttgca ggaacggcgt ttttggttgc agtgtgagcg
    20821 tgcttacacc tggcagccga tctatcaaac atgcgggcgg ttaatggccg tggagctatt
    20881 aacggtggtc acgcatccct tgaacccttc gcaacgcctg ccgccggatc gctattttac
    20941 tgaaatcacc gttagccatc ggatggaggt tgtgaaagag cagattgatt tgctggcgca
    21001 aaaagccgac ttctttgtag agcacggcct gctggcatcg gtcaatattg atggccctac
    21061 gctcatcgcc ctgcgtcagc aaccaaaaat cctgcgccag attgaggagc ttccctggct
    21121 gcgtttcgaa ctggtggaac acatccgcct gccgaaagat tcaacctttg cctcgatgtg
    21181 tgaatttggc ccgctgtggc tggatgattt tggtaccggg atggcaaatt tctctgcact
    21241 aagtgaagtg cgttatgact acatcaaaat cgcgcgagaa ctgtttgtga tgctgcgtca
    21301 gtcaccggaa ggacgcacac tcttttctca gcttttacat ctaatgaatc gctattgtcg
    21361 cggggtgatt gtcgagggcg tagaaacacc agaagagtgg cgtgatgttc agaactcgcc
    21421 cgcattcgcc gcacaaggct ggtttctttc acgcccggca ccgatagaaa cgctgaatac
    21481 ggcggttctg gcgctataag ctgcctcatt ttccgcctgg ctggactatc tttaggactg
    21541 gcacagaaag aatatgagga agcgaacgat gagcaaggca ggcaaaataa ccgctgcgat
    21601 ttcaggggct ttcttgttgt tgattgtcgt ggcgatcatt ttgattgcaa cttttgactg
    21661 gaatcgactc aaaccgacca tcaaccagaa agtctctgcg gagttgaatc gtccgttcgc
    21721 tatccgtggc gatctgggcg tggtgtggga gcggcaaaaa caagaaactg gctggcgcag
    21781 ctgggtgccg tggccccatg tacacgcgga agacatcatt cttggcaatc caccggatat
    21841 tcccgaagtc acaatggtgc atttgccgcg agtagaagcg acgctggccc cgctggcgct
    21901 gctgaccaaa acggtctggt tgccgtggat caagctcgaa aagcccgacg cgcgcctgat
    21961 tcgcctctcc gaaaagaaca ataactggac gtttaatctc gccaacgatg acaacaaaga
    22021 cgcgaatgca aagccgtcgg cgtggtcgtt tcggctggat aatattctgt tcgatcaagg
    22081 gcggatcgcc attgatgaca aagtaagcaa agcggatctg gaaatttttg tcgatccgtt
    22141 aggcaagccg ctgtcgttca gcgaagttac cggatcgaaa ggtaaagcgg ataaagaaaa
    22201 ggtgggcgat tacgtttttg gcctgaaggc gcagggacgt tataacggtg aaccgctcac
    22261 tggtacggga aaaataggcg gtatgctggc gctgcgtggc gaaggaacgc cgtttccggt
    22321 acaggctgat ttccgctctg gtaacacccg tgttgctttt gatggcgttg tgaatgaccc
    22381 aatgaagatg gggggtgtcg atttacggct taaattttct ggcgattcgc tgggtgatct
    22441 ctatgaactg acgggcgttc tgctgcccga tacaccgccg tttgaaacgg atggtcggct
    22501 ggtagcgaaa atcgatactg aaaaatcgtc ggtctttgat tatcgcggtt ttaatgggcg
    22561 cattggcgat agcgatatcc acggttctct gatctacacc accggcaagc cacgaccaaa
    22621 actggaaggt gatgtcgagt cgcggcaatt gcggctggcg gacctgggac cgttgattgg
    22681 cgttgattcc gggaaagggg cagaaaagtc gaaacggtct gaacagaaga agggcgaaaa
    22741 aagcgttcag cctgcgggca aagtgctgcc ttatgaccgc ttcgaaaccg ataaatggga
    22801 cgttatggat gccgatgttc gcttcaaagg gcggcgcatt gagcatggca gcagcctgcc
    22861 gattagcgat ctttctactc atatcatcct caaaaatgct gacctgcgcc tgcaaccgct
    22921 gaaatttggc atagcgggcg gcagcattgc ggcgaatatt catctggaag gcgataaaaa
    22981 gccgatgcag gggcgggcag atattcaggc tcgtcgactg aaactgaaag aactgatgcc
    23041 cgatgtagaa ctgatgcaga agacgctggg ggaaatgaac ggtgacgcgg aactgcgcgg
    23101 tagcggtaac tcggtggcgg cgcttttagg caacagtaac ggcaacctga aactgttgat
    23161 gaatgacggg ctggtgagcc gcaacctgat ggagattgtt gggctgaatg tcggcaacta
    23221 cattgtcggt gcgatatttg gtgatgatga ggtgcgggtg aactgcgcgg cggcgaatct
    23281 ggatattgcc aacggcgtgg cgcgcccgca gatttttgct ttcgatactg agaacgcgtt
    23341 gattaacgtt accggtacgg caagttttgc ttcggaacag ctggatttga ctattgatcc
    23401 ggagagtaaa gggattcgga ttatcacatt gcgttcgccg ctgtatgtac gtgggacgtt
    23461 taaaaatccg caggctgggg tgaaagccgg gccgttgatt gctcgcggag ccgttgcggc
    23521 ggcactggca acgctggtaa caccggcggc ggcgttactg gcgctgatct caccttccga
    23581 aggggaggct aatcagtgca ggacaatttt gtcgcagatg aagaagtgat gataattgcc
    23641 ggatgtctga catccggcaa ttaaacagat ttagattgtt ggcaaagtgt gctttgttca
    23701 tgccggatgc ggcgtgaacg cctccggctt acaaatcctt gcgaattcaa tatattgtat
    23761 ggaaattctg gcctgataag cgtagcgcat caggcttttc actcttatta caacgactga
    23821 tgtcgcgtct catgggtcag cagcagggcg attaacgtca agccagccat cgccgccaga
    23881 tatagcccca ccgcacctaa cccgtagtta gtctgcaacc aggctgcgat atacggcgca
    23941 acggaagccc cgagaatcga cgatacgttg taagagaacg atgctccggt gtaacgcact
    24001 tctgtcggga acagctctgg taacagcgcg cccatcggac cgaaggtcag ccccatcaga
    24061 cttaacccca gcagcagaaa ggcaaaaacc agaatcgggt tgccagaacc gagcaaaggg
    24121 gtaaaggcga atagcgcgaa caggatgatc agcgtggtga tgatcaccat gcttttacgg
    24181 cgaccaaagg catcagccag taatccggcg actggcacca tcacgccaaa accaataact
    24241 gccatcatca gcatccacaa cacttcgtta cgcggcaggc caagcccaac tggcgcggcg
    24301 gcggtactaa aggtcataga gtagaccgtc atgatgtaaa acagcgtata ggttgccagc
    24361 ataatgaacg tacccagtac ggttacgcga acatgtttgg tcagcagcgt acccagcggg
    24421 atcttcacct gttttttcgc tttagcgact ttctcaaaca ccggcgactc atgcagcgac
    24481 acgcgaacat acaggccgat aatgaccagc accgccgaga agataaatgg cacacgccag
    24541 ccccagctca taaactgctc gtcggtcagt agccaggaaa gcagcaagaa agtgccgttg
    24601 gcaaagaaga agccaatcgg tgcgcccagc tgcgggaagg agccgtacaa tgcacgtttg
    24661 cgcggtgggg cgttttcagt cgccagcagc gccgcgccgc cccattcacc acctaagccc
    24721 agaccctgac caaatcgagc cagcgccagc agcagcgggg cgaaaatacc aatcgtggca
    24781 tagcctggca gcagaccaat caccacggtc gaaatcccca tcgttagcaa cgaggcgacc
    24841 agcgtcgctt tacgcccaac gcgatcgcca aaatgaccaa aaacggcaga gccaatgggg
    24901 cgcgcgacga aggcgatggc gaaggtggcg agcgactgta gcgttgctgc cgttggatcg
    24961 ccctgcggga agaagatatg cggaaacaca ataacggccg cagtggcgta aatgtaaaag
    25021 tcgaagaact caatggccgt gccaatgaga gaggcgacaa ggactttatt acgcgagttg
    25081 atcggcgtgt attcttgctc gtggtcgagt gttgtggctg ttgcttgcat aatcttttct
    25141 tattttttgg ctaacgaata gccatattac gcacagcaaa agtgatattt caatgtgtaa
    25201 caaatcgcgg aaatggtcaa aaatcaggca aaaagggaat aatgtttagg ccagtgattt
    25261 ttcttctatg aaatgcttca cataatttta taaatggtgg attaaactgg ttttaggtta
    25321 aataaaagtt accaactgga tttatatgct ggggttatga gttggaatga aattgtttgc
    25381 tcctgaatag atggctaaag aggctctggg aaagagtttc aagaggttat gtgcgcatta
    25441 tagccggatg cgatgctggc gcatcttatc cggcctacgg ggagccaggc cggataaatt
    25501 cgtacgccgc atccggccta ttttaaggct gtgttttccc cggcattcgc gggtcgtctt
    25561 tatattcggc ggtggcaatc cacgccgcgc aaaacagcgt caaacgggcg aagaagtaga
    25621 aaaatgccat cagccccagc acggaaccaa atgctgcgcc agagggtgat ttcatcaacg
    25681 atggcagggt gtaggtcatc acgattttaa tcacttcaaa accaatagca gccagaaatg
    25741 ttccgcggat cagggctttt ttgcgcggac ggtggcgcgg caaccgccag aagatccaga
    25801 agaaaagcag atagttggcg aagatggaaa tcgccacgcc aatcaaccgc catgtcggtt
    25861 tcagccactc aatgctgttc aggtgcaggg cgctaataat catttgctgc gcagaaccgg
    25921 caaccgaggt gatagaaagc gtcacaatca gcgcaatcaa caaaccaatc agcgaaataa
    25981 aatcacgcag atattttacc cagaacttct cctgatcttg cggcgagcgt tcccagacat
    26041 cgcgtgactg ggcgcgaatc gcttcacgca ggttacccat ccagttgatg ccggaataaa
    26101 gtgccactgc cagaccgaca agccctacag tcgtacgctg ctgaacggcg gtgttgatgg
    26161 tgtttttcaa tgtggcggct agcgtcggat cgctgatgtt ttgcagaatt ttgtcgaaga
    26221 tatcctgtag caacatcgga tgggaggcga gcacaaagcc ccctgcggca aacgacacca
    26281 tcaaaatggg gatcatcgac aaaaatgaga aataggtgat agccgcacca aactggttac
    26341 ccagccgatc gttaaagcgt tctgtcgcgc gaatcaggtg cgcaataacc ggttggcgtt
    26401 ggactttctc ggcagtggtg gtgacggttt ccagcgcctg gctaactttg ccgcctttct
    26461 cgctattatc caactgctta atcggctcgt gctccagatc ctgggtggga cgtttgatct
    26521 cgttttcctg cgtcatccgc tcttttgtcc ttctgtcgtg gtcattctta aaagtatagt
    26581 cggtcagtcc aggtactctt tcattacgcc agccagccac tgcataaaca ggtttacacg
    26641 ccgggaaagc tcccgacgct gcggataaac cagtgaaagg gacagcggct cggcacggta
    26701 gccaggcaac acttcaataa gccgcccggc acgcagggct tcgcgcacgg caatgcgcgg
    26761 gatctgaata atccccagac cggcaagacc ggcggcgaga tagttttcgc tactgtttac
    26821 cgtcaacatg ctgccagact taaaccactg gacgccatta acgctggcaa cctcaaaacc
    26881 taacggatgt acacccaggt gcggtgtata acgcactatt gcgtgtgaag tcagatcatc
    26941 ggggctttgc ggataaccaa agcgcgtcag atagtgcgga ctggcacagt tgaccatggt
    27001 cagtttaccg aggggacggg cgataacgcc atcttccggt aatgcgccag tgcgtatcac
    27061 gcaatcaaaa ccatcatgaa gaatatctac cggacggtca tggctactca gttccagctc
    27121 aattcccgga tgcagataga gaaattccga caagcgcggc agtaacaggc ttttcgcgat
    27181 tcctgacggg atgtcgatgc gtaatttacc gctgatactg gtggcatcct gttgaaacag
    27241 accgtccagt tcgctgagat tactcaacac atcttttgct cgttgataat aggtcatgcc
    27301 ttctggcgtg agtttgaccc gtcgcgtggt gcgctggaga agctgggtgc caagttgatg
    27361 ttccagtgcc tgtatctggc gcgaaacact tccctttggc aaagcaaaga aatccgccgc
    27421 gcgggaaaaa ctttccagct ccgcgacttt gatgaacaac tgcattgcgt gaattttatc
    27481 catttctttg accgattgtt gttcacaacg aaacagtagc gtgcatatcg cattgtttat
    27541 tgttttttct aacatctaat gccgggtttc acaatgttgt catgatgaat gtggcgattt
    27601 ctcagcagga aaagggagga atagctttat gagaaaggta aattccctta aacagagcgt
    27661 atttttcagc gattcccttt aaagtgaata gaagatgtat tggctatttg tgcttatttt
    27721 tatctcattg ccgtttgtta tttttgttta tggtcgcgga atttcatttt taattgcatg
    27781 cgtactaact accgatataa ggaaatcctc aaaaatgttt taaatagtgc cctcgacatg
    27841 taatttcagg cgtttagctg taactattta tatcggtaac tattttctac gtgtcatctc
    27901 tgtagaatgg ccaccgccaa atggcgaatt cttatttttt ctcgcgggta atacccttcc
    27961 actacttaag tctttttaac gtattcaggt ggagattcag ttatgcaaat agtcatgttt
    28021 gacaggcagt caatatttat tcatggaatg aaaatcagtt tacagcatcg tattccagga
    28081 gtgagtattc agggggccag tcaggcagac gagttatggc aaaagctgga aagttaccct
    28141 gaagccttag tgatgctcga tggcgatcag gatggtgagt tttgctactg gttgctgcaa
    28201 aaaactgtgg tgcaatttcc tgaggttaag gtgttaatta cggcgacgga ttgcaacaaa
    28261 cggtggttac aggaagttat tcattttaat gtgctggcca ttgtgcctcg tgattcaacc
    28321 gtcgagacat ttgcgttggc ggtaaatagt gcggcgatgg ggatgatgtt tctgcctgga
    28381 gactggcgaa cgacgccgga aaaggacatt aaagatctca aatcgttaag cgcccgccag
    28441 cgggagattt taaccatgtt agcggcgggc gaatcaaata aagagatcgg cagggcgctg
    28501 aatatcagta ccggaacggt aaaagcgcat ctggaatcac tgtatcgccg tctggaagtc
    28561 aaaaatcgca cccaggcggc aatgatgtta aatatctcct cctgaagagg ataattttac
    28621 agccagcagg aagttagcgg ctggctgtaa aaatattatg gttcgccgta caaaccaatt
    28681 aaacggcgta ccacaccgtt agtccagcca aacccatcct gcaacggata ctcgccaccg
    28741 ccgccttcgc gaggaacacc atcggcaata tggtatttct cgatcagttt gtgctgttcc
    28801 agatagaact gattcaccgt cttcagccag ttgcgcgcga tttcatcacc cagaaggtca
    28861 tcgccgtaca tcttaaatcc ctgaattgcc atccactgta acggtgccca gccgttgggt
    28921 ttatcccact gttcaccggt ttcgtactcg cttgccagaa tcccgccagg tgtcagtaac
    28981 cggctgcgca cggcgtttgc cagacgatcg gcctgttcat ggttcgccat accgacatag
    29041 agcggcacaa tggcggcagc ggaaaacagc gccagttgct cgcgtcgcca gtcgtaatcg
    29101 cggtagatac cgttttcatc atcccagagg taacggttta ccgcatcgcg acgggcactg
    29161 gccttctggc ggaacagtgc ttctgtctct ttctcgcctt tcagtgccga gatgttggcg
    29221 atggcgctct ccagtttaaa caggaaggca ttcagatcga tggggatgaa ctgggtggta
    29281 cgaatgctcg ccagacgacc agtatcacgc agccaacggg aagagtaatc ccaaccggag
    29341 gccgcccccg cacgtaaatc gcggtacacc tcgttaggcg ggcgaccaga atgtttcgcg
    29401 gtttcaacgt cctcaagcca ggattcgtca cgcggcgtgt cgcgatcgtc ccagtaacgg
    29461 ttgagcagcg agccgtccgg catccgcaca acatggcgat aggcctgatt agggatcaac
    29521 gattctgcac cgtccatcca gaaggcatat tccattttca ggtggtcgag atagcggcgc
    29581 gcgccgcgta caccatcttc ttcaaacaac tccaccatca gcgcaaaaac cggtggttgc
    29641 gagcggctca aataataggt gcggttgccg ttggggatgt ggccgtagtt ttcgatcatc
    29701 caggcgaagt tatcggccat gcatttcagc aaatcttccc gaccactttc cgccagcccc
    29761 agcatggtga aataggaatc ccaatagtag gtttcgctaa aacggccgcc cgggacaata
    29821 tatgactgcg gcagcgccag cagagaagac cacggaatgt gatcctgtgg ttcacgggtt
    29881 agcaccggcc acagctggtc gatatgctct ttcagggaat tttgcgggtc cgatacatac
    29941 tcgctggagt agacctccgg cagccagaag tggttttcaa caaacttgcg caagtcaaaa
    30001 tcacgatgac ggcgcacttt acggtagcgg attaaaatat ccagcgggtc cattttgggt
    30061 gcgcagtcgg gaaaggtttt actgtcgggg aaaattttcg ccgactgaac atgctcgaac
    30121 agttcgagat agcgatcggc aggcgtcagc gcatcagagg cgggcagccc ttcaatcatc
    30181 tcgggttccg gttctgcctc gatcatctca tccagtttta attcatacgg gtccagctca
    30241 tagcagagat cgacctcgat catcagttcg tctggattag ggttttgaat tttctgattg
    30301 agcataagga tccgacctcc gaaattcgtc gctaattatc gggcttttct ttaagggtag
    30361 tcattcgctc cgcctggtgg gcgacaaagc gtgcggtgga tcacgtttat taacctgcca
    30421 aaaaatataa cgcactaata tcaatggaat ttataaaaat acggatttcg tgttgttttt
    30481 cattttcaga acattcaatc ctgctctcgc cgcaatcatg atatgccatt cctgatctgg
    30541 gtaataggca ctggctatct tattgatagt ttatattcat gtaattgatt gattcctatc
    30601 aaaaagcata tctccctgtt ttttatgatg gctttgtctc gcagagacgt ttgcagcatt
    30661 ctggaaaatt ttctgggtca caataactca ctaccgtgag ggaagaataa tgaaaatggt
    30721 ctcacgtatt accgcgatcg gcctggctgg cgtcgcgatt tgctatttag ggttatctgg
    30781 ttatgtgtgg taccacgata ataaacgcag taaacaggcc gatgttcagg catctgctgt
    30841 cagtgaaaat aataaggttt taggctttct ccgcgaaaaa ggatgcgatt attgccatac
    30901 gccttcggca gaattacccg cctattatta tattcccggc gcgaaacagt tgatggatta
    30961 cgacataaag cttggatata aatcttttaa cctcgaggcc gtgcgtgcgg ctctgctggc
    31021 taataaaccc gtttcgcaaa gcgatctgaa taagattgaa tgggtgatgc agtatgaaac
    31081 tatgccgcca acgcgttata ccgcgctaca ctgggcgggt aaggtgagtg atgaagagcg
    31141 ggcggaaata ctggcctgga ttgcaaaaca gcgcgcggaa tattacgcca gcaatgatac
    31201 tgctccggag catcgcaatg aaccggtgca gcccatcccg caaaaactgc ctaccgatgc
    31261 gcaaaaagtg gcgttgggtt ttgcgctgta tcacgatccc cgtttatcgg cggatagcac
    31321 catttcatgc gctcattgcc atgcgttgaa tgcggggggc gtcgatggca gaaaaacatc
    31381 gattggtgtt ggtggcgcag ttgggccgat taacgcgccg acggtattta actcagtatt
    31441 taacgttgag cagttctggg atggtcgtgc ggcaacattg caggatcagg ctggtggacc
    31501 gccgttgaac ccgattgaaa tggcgtcgaa atcctgggac gaaattattg ctaagctgga
    31561 aaaagatccg cagcttaaag cgcagttcct cgaagtctat ccgcaaggtt tcagtggcga
    31621 aaatattact gatgccattg ctgaatttga gaaaacatta attacgccgg attccccatt
    31681 tgataaatgg ttgcgtggag atgagaatgc tctgacggcg caacagaaaa aaggctatca
    31741 attatttaaa gataataaat gtgcaacttg tcatggtggt attattctcg gcggacgttc
    31801 ctttgaaccg ttggggctga aaaaagactt taactttggt gaaattacgg cggcggatat
    31861 tggtcgtatg aatgttacta aagaagagcg tgataaattg cgtcagaaag tacccggttt
    31921 acgtaacgtt gctttaacgg caccgtactt ccatcgcggt gacgtgccga cgctggacgg
    31981 ggcagtgaaa ctgatgctgc gctatcaggt aggcaaagag ctgccgcagg aggatgtgga
    32041 tgatatcgta gctttcctgc acagtctgaa cggggtttac atgccgtata tgcaggataa
    32101 acaataatta atttgatcgc ccgaacagga gtgtttgggc gatttttatt acgataataa
    32161 agtctgtttt taatattatc atattaaatg tttatattat aaaaggtcgt ttttctgctt
    32221 aggattttgt tatttaaatt aagcctgtaa tgccttgctt ccattgcgga taaatcctac
    32281 ttttttattg ccttcaaata aatttaagga gttcgaaatg gaccagaagc tgttaacgga
    32341 tttccgctca gaactactcg attcacgttt tggtgcaaag gccatttcta ctatcgcgga
    32401 gtcaaaacga tttccgctgc acgaaatgcg cgatgatgtt gcatttcaga ttatcaatga
    32461 tgaattatat cttgatggca acgctcgtca gaacctggcc actttctgcc agacctggga
    32521 cgacgaaaac gtccataaat tgatggattt gtcgatcaat aaaaactgga tcgacaaaga
    32581 agaatatccg caatctgcag caatcgacct gcgttgcgta aacatggttg ccgatctgtg
    32641 gcatgcgcct gcaccgaaaa atggtcaggc cgttggcacc aacaccattg g
//
LOCUS       DAFGPF010000052        31973 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFGPF010000052 DAFGPF010000000
VERSION     DAFGPF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31973
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.052"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            633..1082
                     /locus_tag="LSX49_002632"
     CDS             633..1082
                     /locus_tag="LSX49_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001523573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169029.1"
                     /translation="MKDNIHTAVIMAGEFLSANEWIRRKNQLKTSVHPASVASFAPYG
                     FNINQCDDDGNLWTNFPRPHIKLKIAPGKTACFLCRREELLFGYDEAHNHYQPNLNLV
                     LFVKNHGLHKDVYLKSHDDKSEYDSRILCNEKFTTYDFRKNRSRYSF"
     gene            complement(1267..1485)
                     /locus_tag="LSX49_002633"
     CDS             complement(1267..1485)
                     /locus_tag="LSX49_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBL7169030.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKSDRQRGEVVGVEEQGKWHEE"
     gene            complement(1882..2160)
                     /locus_tag="LSX49_002634"
     CDS             complement(1882..2160)
                     /locus_tag="LSX49_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169031.1"
                     /translation="MSTFNTRKDRDRNGKAKPHKHSGIPTLTGKWRHPSMDCWVNYST
                     PGDHEWKRLYTTLRRRADDRRQCHRVMQGDDPEGIVWFPDCYPQIYYY"
     gene            complement(2519..2809)
                     /locus_tag="LSX49_002635"
     CDS             complement(2519..2809)
                     /locus_tag="LSX49_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7169032.1"
                     /translation="MDKALFERLTHSMAQMNEIIEGTRQPSRTFEVDAMKIKEIRRAS
                     GLSQSKFADLISVSVDTLRNWEQGRRSPTGPAKALLRAIANDPQHVLQALNR"
     gene            complement(2810..3121)
                     /locus_tag="LSX49_002636"
     CDS             complement(2810..3121)
                     /locus_tag="LSX49_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL7169033.1"
                     /translation="MLFIETEIFTEDVQKLLNDDEFSRFQFFLALNPDYGEVIPETGG
                     LRKVRWVSGGKGKRAGVRVIYFHQVKHYEIRLLLIYRKGIKDDLSPQEKAMLRLLNTR
                     W"
     gene            3350..4258
                     /locus_tag="LSX49_002637"
     CDS             3350..4258
                     /locus_tag="LSX49_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7169034.1"
                     /translation="MALEKGIAELVEEFIAAGRPSSRQQSITQRREGYIASAVLAGET
                     ETRVDIQTIELEGMTLRIVSPLNAPTLLPTIIYYYGGCFVSGGFATHDNQLRQLAYYG
                     QCRVIAVQYRLAPEHTFPAAHDDAQRGAELVRQHAERLGVDKQRITLAGDSAGGHLAL
                     VTALRLKRAGEWQPAQLILIYPMLDATAHFESYIRNGHDYIITRDTLLSGFEMYLPGI
                     ERRHPEASPIWRNDFNGLPPVHIITAEYDPLCDEGEALYHRMTGQGVQCTCQRYLGVI
                     HGFFQLGGISEAARSALRDVAWRAGR"
     gene            complement(4322..5263)
                     /gene="fabY"
                     /locus_tag="LSX49_002638"
                     /gene_synonym="yiiD"
     CDS             complement(4322..5263)
                     /gene="fabY"
                     /locus_tag="LSX49_002638"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HBL7169035.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(5308..5745)
                     /gene="dtd"
                     /locus_tag="LSX49_002639"
     CDS             complement(5308..5745)
                     /gene="dtd"
                     /locus_tag="LSX49_002639"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBL7169036.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQDMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            complement(5742..6614)
                     /locus_tag="LSX49_002640"
     CDS             complement(5742..6614)
                     /locus_tag="LSX49_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HBL7169037.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            complement(6608..7207)
                     /gene="yihX"
                     /locus_tag="LSX49_002641"
     CDS             complement(6608..7207)
                     /gene="yihX"
                     /locus_tag="LSX49_002641"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HBL7169038.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRVPLATLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLRAEGFSPDD
                     TVFFDDNADNIEGANRLGITSILVKDKTTIPDYFAKVLC"
     gene            complement(7348..8235)
                     /locus_tag="LSX49_002642"
     CDS             complement(7348..8235)
                     /locus_tag="LSX49_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001309103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HBL7169039.1"
                     /translation="MKTERKNEHYLALQQAFDAPWPGPVGELVTLEKGNIHLQIYPHD
                     GARITSLKAFGSEVLRQWQPQRRAFQYGCFPMVPWAGRLGNATLNAGGQCYSLPANKP
                     PHALHGMACYSTWEIIDKTADSLTLRMPLTSPWPWQGEVIQTFLLENDALVLQLEVHS
                     YADTFPASAGWHPWFAKKLTPQNTESLQVLFDADWQEEAGSDELPTGNRISPQVGPWD
                     DCFGFYDGVKVKLLWPGKLAMTMTSSANSLVVFDKQPDATCINPLTQAPNAINLTPEF
                     VTPDKPLVIETRWQFTPES"
     gene            complement(8225..9574)
                     /locus_tag="LSX49_002643"
     CDS             complement(8225..9574)
                     /locus_tag="LSX49_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HBL7169040.1"
                     /translation="MSEKLPAPREGLSGKAMRRVVMGSFAGALMEWYDFFIFGTAAGL
                     VFAPLFYPDSDPFIGLIASFATFGVGFLTRPLGGIVFGHFGDKIGRKITLIWTLAIVG
                     CSTFLIGFIPTYQEIGIWAPLILMVLRLIQGFGLGGEYGGAALMTIESAPESRRGFLG
                     SLPQTAASVGIMLATGIFALCNHFLTSEQFLSWGWRIPFWLSAVMLIVGLFIRLHTEE
                     TLDFQKQKTTNNKEKSVPPLIELFKKHPRNILLALGARLAESVSSNIINAFGIVYISS
                     QLALSRDIPLTGMLIASAIGIFSCPLVGWLSDRIGQKSLYLSGAGFCVLFAFPFFLLL
                     DSKSTLIIWCSMILGYNLGPTMMFAVQPTLFTRMFGTKVRYTGLSFAYQFSAILGGLS
                     PLIASSLLALGGGKPWYVALFLFAVSVLSFVCVWLIEPTDEQETASYRYIREQSHEN"
     gene            complement(9673..11106)
                     /locus_tag="LSX49_002644"
     CDS             complement(9673..11106)
                     /locus_tag="LSX49_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169041.1"
                     /translation="MSQITSPATYSISRPQDVIDIVNKNSAINTSIGVIFIALGGILI
                     DAYQAAMVGFGNKYIAAQFGISPGLAATVNASVLIAALIGGLLANRVINRFGQKRAFI
                     IGMGLCTIGAAAVAIAPSIWWVLVCRVIMGFGLGIDFPLATNAVAELRGSTSKKTGTS
                     VNLWQMAWYVSTTVVYLVLLPLLLSGIAEEQLWRYGIFIGAIFAVIFMILRYFFIGES
                     AMWAARVGRYQEACDILGKRYGVQARVAASGTTEAKFSEKAENKYSGGYGILFNDRYR
                     KRTILGCVVATMQAWQYNAVGVYLPLTLAGIISGGLTGALTGSAVVNALCGVTGGMIG
                     SFILQRLGTRRQSMYGFAVVTLALLSLGALATTNPWLSLGLLGSIIFFHSAGPGGLGM
                     TIATLSYPPAIRPTGVGFARAIMRTGAIAGLIFWPMLWGALKTEAFYWLAIVPFLGFL
                     TCVLINWEPLGANVDAEDAEVLAELKK"
     gene            complement(11176..12186)
                     /locus_tag="LSX49_002645"
     CDS             complement(11176..12186)
                     /locus_tag="LSX49_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001494590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBL7169042.1"
                     /translation="MDKITQVLFSDIGKVTTQYVEVPHQQLKPHEVRIAPVFYGICGS
                     DLHVLKGGHPFAKPPVVPGHEIAARVTEVGSDVKNVQPGDHVVVDPIMACMECRACKA
                     GRFNLCEPPQVAGFRAPGFARSQHIVPARNCHVAPASLPLKVLAFAEPAACARHCVNR
                     MPKASLESVLVIGAGTIGLSIVQALRIMGAGKITVIEPDAAKRALALKLGAAEVWAPG
                     ELAADVRFTGAIDVVAAQATLNDACTRVYAGGTVVCMGVPSGPREIPLPMMQRFERDL
                     LNSGMYIPEDFDAVIEWLADGRFDTSELVTDLFAIEDAAAAFERAQQNDSIKVMLQFA
                     PE"
     gene            complement(12219..13106)
                     /locus_tag="LSX49_002646"
     CDS             complement(12219..13106)
                     /locus_tag="LSX49_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBL7169043.1"
                     /translation="MSSHFTPFTLKDISRPGGGFAMLAVDQREAMRLMFAAAGQPKPI
                     ADSVLTDFKVAATRILSPYASAVLADKQFCLEQIVEQGAVANSCGLIVAADLFIPGNG
                     IPVDSVEIDMSVDPHKAREMGAKAMKLLVLWREDEPAEERLAMVDKFVRRCRSAGLVS
                     IIEPVVRPPRRGWDFDRESAIVAAAAELGGTEADLYKAEMPLGGKGDEKTLLAACQQL
                     NDQMKMPWVILSSGVDADIFGRAVSIAMKGGASGFLAGRAVWASVVGAQDPQTMLRDV
                     SVPRLQRLAEIVDEGIAQR"
     gene            complement(13131..14009)
                     /gene="yihU"
                     /locus_tag="LSX49_002647"
     CDS             complement(13131..14009)
                     /gene="yihU"
                     /locus_tag="LSX49_002647"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001318159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HBL7169044.1"
                     /translation="MATIAFLGLGQMGSPMANNLLQKGHSLQVFDVNTQAVDALVTQG
                     ATAAQTPAEAAASAEFIITMLPNGDIVRQVLLGEKGVCETVSSDALVIDMSTIHPLQT
                     DALIRELQEKGINMMDAPVGRTSVNAIDGTLLILAGGTDEQIARARPILMCMGNELVE
                     AGGPGMGIRVKLINNYMSIALNALSSEAAVLCESLGLNLDVAIKVMSGTAAGKGHFTT
                     TWPGKVLKGDLSPAFMVDLALKDLRIAVDVARKTGAPLNMGIAAESYYAAASQDGKGR
                     QDWSALLNQVRQQAGL"
     gene            14182..15078
                     /locus_tag="LSX49_002648"
     CDS             14182..15078
                     /locus_tag="LSX49_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL7169045.1"
                     /translation="MTRIACVGITVQDRIYSLPTLPEGGGKYQANHYLEIGGGPAATA
                     AVAIAKLGVEVDFIGRVGDDSCGNTLLAELEGWGVNTAFCRRYPNARSSQSAILVDQH
                     GERIIVNYPSPDLGTDAEWLEAIDFSRYDLILADVRWHSGTEKAFSLARLAGVTTLLD
                     ADMTPQDISPLVALADHAVFSTPGLKRMTGLQSPEEGLFQATTQTAGKVYVTLGSEGS
                     LWIEDGHLCQQEAFSVNVVDTTGAGDVFHGALAVALAEKMPTKEAIRFASAVAAMKCT
                     QPGGRAGIPNREQTESFLSLYA"
     gene            15118..15906
                     /locus_tag="LSX49_002649"
     CDS             15118..15906
                     /locus_tag="LSX49_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7169046.1"
                     /translation="MSIIEVTGNPRHDQLVHLIAERGYMNIEELAQLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRVSSVMNTAFEQRELSLTAEKRAIAEAVADYLPERCTVFI
                     TIGTTVEAVARALLNRRDLRIITNSLRVAQILYKNQDIEVMVPGGTLRAHNGGIIGPG
                     AVDFIEGFRADYLITSIGAIEHDGTLLEFDVNEALVARTMIKHARNTLLVADHTKFTA
                     SAAVSIGNARNVRAFFTDAPPPNSFCQLLSEENVELVVAEQEVS"
     gene            complement(16014..17837)
                     /gene="typA"
                     /locus_tag="LSX49_002650"
     CDS             complement(16014..17837)
                     /gene="typA"
                     /locus_tag="LSX49_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HBL7169047.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            18210..19619
                     /gene="glnA"
                     /locus_tag="LSX49_002651"
     CDS             18210..19619
                     /gene="glnA"
                     /locus_tag="LSX49_002651"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HBL7169048.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            19793..20842
                     /gene="glnL"
                     /locus_tag="LSX49_002652"
     CDS             19793..20842
                     /gene="glnL"
                     /locus_tag="LSX49_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HBL7169049.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRITESIHKVAERVVTLVSMELPNNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            20854..22263
                     /gene="glnG"
                     /locus_tag="LSX49_002653"
     CDS             20854..22263
                     /gene="glnG"
                     /locus_tag="LSX49_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HBL7169050.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESNVPE
                     STSHMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            22375..22485
                     /locus_tag="LSX49_002654"
     CDS             22375..22485
                     /locus_tag="LSX49_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HBL7169051.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(22718..24091)
                     /gene="hemN"
                     /locus_tag="LSX49_002655"
     CDS             complement(22718..24091)
                     /gene="hemN"
                     /locus_tag="LSX49_002655"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBL7169052.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEQQW
                     DLLFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(24280..24789)
                     /gene="yihI"
                     /locus_tag="LSX49_002656"
     CDS             complement(24280..24789)
                     /gene="yihI"
                     /locus_tag="LSX49_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HBL7169053.1"
                     /translation="MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGS
                     RAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELL
                     ETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQE
                     DMMRLLRGN"
     gene            25371..26003
                     /locus_tag="LSX49_002657"
     CDS             25371..26003
                     /locus_tag="LSX49_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBL7169054.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            complement(26385..29171)
                     /gene="polA"
                     /locus_tag="LSX49_002658"
     CDS             complement(26385..29171)
                     /gene="polA"
                     /locus_tag="LSX49_002658"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL7169055.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQPPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAARPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
     gene            29529..30461
                     /locus_tag="LSX49_002659"
     CDS             29529..30461
                     /locus_tag="LSX49_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBL7169056.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVRGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWALDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQDK"
     gene            complement(30502..31932)
                     /locus_tag="LSX49_002660"
                     /pseudo
     CDS             complement(30502..31932)
                     /locus_tag="LSX49_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418298.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
BASE COUNT         8060 a         8150 c         7654 g         8109 t
ORIGIN      
        1 aggtgagtag acatttcagt aaaagtatgc cttacaatgg attacatctg gtagttaata
       61 gagaaaatga tataaatgca ctgcgacaga cacgcgttta tacaacccgt gcaccgtgga
      121 gtgcacaaga aatggcaaga caaaagaact atatccccca aatatggctt tattgccata
      181 attatatggc ttataaaact gtgtctggtg caaagaacaa accacaacca tttatttttt
      241 taagaaacaa ttggctattt aaatggccaa aagaaatgga taaacgttcc agaagctcaa
      301 agatactgtc tgaataagca taataatgaa ggatttcgac tatgattaac aaacttactc
      361 ttccttggcc ggtattattt ttagaatttt ttgtgcgaga agttgccttt aagggtaagg
      421 gaattgttcg ttctacatta ccagcagatg cccattttta taccggtggg tcaaaagccc
      481 tgcgttatca cctacaacca ggaaaccaat ggccaaacta tatatggcat gatgatatag
      541 gtgatattgt accgtttcct ctaccctcac ttccgcttac atttaccgct aaccgaccca
      601 catttaattc cagagaatta gcggataaat ggatgaagga taatattcat accgctgtca
      661 tcatggcggg ggaatttctg tctgctaatg aatggattcg ccgcaaaaac cagcttaaaa
      721 ctagtgtaca ccctgcgtca gttgcttctt tcgcacccta tggctttaac attaaccagt
      781 gtgatgacga tggcaatctt tggactaatt tcccacgtcc ccacatcaaa ttaaaaatcg
      841 caccaggaaa aacagcttgt tttctctgcc gccgggaaga gcttttattt ggttatgatg
      901 aagcacataa tcactaccag ccgaatctta atctggtttt atttgtgaaa aatcatgggt
      961 tgcataagga tgtttaccta aaatctcatg acgataaaag tgaatacgat agcagaatat
     1021 tatgtaacga aaaatttacc acttatgatt tccgtaaaaa ccggtccaga tacagctttt
     1081 gatagtttat tatcctggat gatatcagga gcgatatcta taaagtttat gcattccctg
     1141 tgatcaattt ttcctgttag tgagcacaaa ttcaatctga ttgatgccag aataaaggca
     1201 tctggcatgt tgattttatg ttccagaatg acaaaacatt gctgttaata agcacgactc
     1261 tttttgtcat tcctcatgcc acttaccctg ttcttcaaca ccaactacct cacccctttg
     1321 cctgtcactt tttgccttac gcaccggaaa ttgctgacgc tccagatatt gctctaccgc
     1381 ttcgcgtaaa attgcagagc gcgaaacctt acgccagccc cgaagcttgt tcagccgttt
     1441 aattgcctct tctgataaat gaagaaaaac cgtattcatc gccattgcca ccaccttaca
     1501 tatattactc attaatgtat gtgcgaaaat tacgccgaaa aatcatttaa aaaaagcgga
     1561 tttttgcatg tcgttttgtt tttgcgagac tgcatccaaa gataatgtaa cagttgcagt
     1621 tatttcaatt gttactcaaa aatggtttat tacttttaat taagcggggg cacatctaca
     1681 gaaaagaaac aacaaataat aaggatgaat tatggatgct ataaatattt tatattcaag
     1741 aatatttttt tgattgggtc ttcatttgct tcatcaggat ggtgtacccg aaaaagtcag
     1801 cagctttacc gcaccagggg ttaaggtgaa atctaccatt cataacgacc ggtcagtgcc
     1861 gcaccaaccg gtctttaatt gttagtagta gtaaatttgt ggataacagt ccgggaacca
     1921 gacgattcct tccggatcat ccccctgcat tacccgatga cattggcgtc gatcatctgc
     1981 gcgacggcga agcgtagtat agagccgctt ccattcatga tcgcccggtg tactgtagtt
     2041 tacccaacaa tccattgaag ggtgacgcca tttacctgta agtgttggga tccctgaatg
     2101 cttatgcggc ttcgctttac cattacgatc cctatcttta cgcgtattaa acgtggacat
     2161 ttttagtctc ctgttaagag ttctaaaaat gtgcttcctt aaaatagttc atcattttcc
     2221 cttaattcgc atagcgtgct tttgcacgaa tttccgatac gcggggacca ttatgatagc
     2281 gtcgatgccc acacatccaa caagaacaaa tacagggagt acgaaagcaa atacctgatg
     2341 cttttttgct tccatcgcct gcagtgcgat aacgacagcg gatttttttt aatcgcacca
     2401 tatgatggcg acgttcagca cgattacggg tcatagcaaa actcctgaac aggcggcact
     2461 atgccgcttt cataggagtt ctgaatgctg gtgctttctg tatggcataa ccatgcctct
     2521 aacggttaag tgcttgcagc acatgttgcg gatcattggc aatcgctcgc agcaaagcct
     2581 ttgcaggccc ggtcggtgaa cgtcgcccct gctcccagtt acgcaacgtg tctacgctta
     2641 cggaaataag atcggcaaat ttagattgtg acaaccctga agcgcggcgt atttctttga
     2701 ttttcatagc atcaacttca aaagtccgtg aaggctgtcg cgttccttca ataatttcat
     2761 tcatctgggc catgctgtga gtcaaccgct caaaaagtgc cttatccatt taccacctcg
     2821 tatttaacaa ccggagcatt gctttttcct ggggagacag atcatcttta atacccttac
     2881 gataaataag cagtaatctg atctcataat gtttaacctg atgaaagtaa ataaccctga
     2941 caccagcacg tttccccttt cctcctgaga cccatcgaac ctttcttaac ccaccagttt
     3001 caggtattac ctcaccatag tcaggattca aggccaggaa aaactgaaaa cgactgaatt
     3061 catcgtcgtt cagcagtttt tgaacatctt cagtaaaaat ttccgtttcg atgaagagca
     3121 taattatacg ccattggctt agagcaacaa tcctttttgt acgtcattga cgtaccattg
     3181 aaaccactag cttactgata gtgctccagc aaaaccacgt ctctgccggg tttgtcttta
     3241 catttgcgag gcgctttcca gatttttcac gcccgtgaat ttccctgtat ccatccagca
     3301 aaaacgggtg tataaaactg tacattcata cagcaaaatg agttctacta tggcactgga
     3361 aaaaggaatt gcagagttag tcgaagagtt tatcgctgcg ggtcgcccct catcgcgcca
     3421 acaaagtatt acgcagcgca gagagggcta tatcgccagc gctgtccttg cgggtgagac
     3481 agaaacgcgg gtagatattc agactatcga acttgaaggg atgaccttac gaatagtgtc
     3541 accgctgaat gccccgacat tactcccgac gataatttat tactacggtg gctgttttgt
     3601 tagcggcggg ttcgcaactc acgacaacca gctgcgccag ttagcctatt acgggcaatg
     3661 tcgggttatt gccgtccagt atcggctggc accggaacat actttccccg ccgcccatga
     3721 tgatgcacaa cgaggtgcag aattagtccg gcaacacgcc gaacgactcg gcgttgataa
     3781 acaacgaata actcttgccg gtgacagtgc gggagggcat ctggcgctgg taactgcttt
     3841 gcgattgaag cgtgctggcg agtggcaacc agcacaactc atcttaattt atcctatgct
     3901 tgatgcgact gcgcatttcg aaagctacat acgcaatggt cacgattaca tcatcacacg
     3961 cgacacttta ctgagcggct ttgagatgta cctgccaggc attgaacgca ggcatcctga
     4021 agccagccct atttggcgca atgatttcaa tggcttgcca cctgtacata tcattaccgc
     4081 tgaatacgac ccactttgcg atgaaggtga agcgttgtat caccgcatga cagggcaagg
     4141 agtgcaatgc acctgccaac gctaccttgg cgttatccac ggattttttc agttaggtgg
     4201 tatcagtgag gctgcgcgat cggcgttacg ggatgttgcc tggagagcgg gaaggtaact
     4261 ccggaccagg gcccagaaaa ggttttcaga ttgaaaacct tttcagtcaa gtaaaacgcc
     4321 cctactcttc ttcgttcccg ccctcttcat acgggccaaa tggcttcgcg ggcagaacga
     4381 tatacgtgcc ttcaaacact gcacccggcg tctcgtcgcc aaagatttct acttgcatct
     4441 gcacccgtgc ttttcgtccg cgcgccagac ggtcgagatc gccacttaag gcaccaaggt
     4501 cggctaccgc atggggtttt ccgctaatcg gcttgctgta gcggatatgc gcatccgcca
     4561 gaataatcgt tccgccgagg tggcgttcgc gcagcatcag ccagataagc ccccaaccgg
     4621 tgagcgtagc cagcgagaat aaactcccgg caaacagcgt gtgatgcgga ttctgattgc
     4681 cggtttccgg catggtggtg ataaattttt gcccggtata ttgctgaatg cgcacaccca
     4741 ttttttcgct taacgggata tgttcatacc acgcttgctg gagctgggcg caccagtcgc
     4801 cgcgatgaag aatatcatcc agagtggcga cgggtttaat catcagaaaa tggcgaatcg
     4861 gcgtggtggt tggcgtggtg atttcaccct gattaacaaa ccccagcttg gcgaaaaact
     4921 ccaccgcgtc ttcacgggcg ctacaggtca cgcgcttaac gccttcctga cgtgccaccg
     4981 actccagggt catcgccatc agcgtgccta accctttgtc ctgcacgtcg ggatgaacgg
     5041 ccataaagcg aatggacgct tcattgtcgg cattaatata cagtcggcct accgctacca
     5101 gattaccctg ctcgtcgacg accatctggt gatgcgccat cgcatcccac gcgtcgcgtt
     5161 ccgaaccttt tggttgatgc aggggcttac gcaacatttc ccagcgaaac tgatagtaac
     5221 gctctaattc ttcttctgtt tgtggaaccc gaaggtgata catagcgata ctctctcttg
     5281 tttcccgtga caaccctgga agctggctca tacctgcaac cagaatgtca cggggccatc
     5341 attgaccagc gatacctgca tatccgcagc gaagcgtcct gtttgcgtgt tcatatcttg
     5401 ctgacggcag cgttcgacga aatagtcata taacgcctct gcgcgatccg gtgatgcgcc
     5461 tttggagaaa cttgggcgca tcccccgttc ggtatctgcg gcaagggtaa actgggaaac
     5521 caccagtaca ctgccgcccg cctgttgcac gttgagattc atcttgcctt cggcatcgct
     5581 aaagatgcgg tagccgagta cacgctcgca cagacggttt gctttctgtt cgtcgtcatc
     5641 cttttcgaca cccaataaca ccaaaagtcc cgcgccaatt tcacccgtca cttctccctc
     5701 cacggtgacg ctggcacggg ttacgcgttg aattaatgca atcatggttc gtcgtcttct
     5761 tcttgttcag cagcttgttt taatttgcgg tattccccga gagtgacagt aatttccgcg
     5821 ccaagcaaga cgatacacca tgtccagtag acccaaacaa agagaatggg gatcaccgcc
     5881 agcacgccgt aaatgagctg atatgacggg aacatggtga tataaagcgc gaaacctttc
     5941 tttcctgctt cgaacaggag cgcggcgaca aacgcgccga caatcgcgtc gcggttaggt
     6001 acgcgaatgg taggaacgat gctgtacagc aaccaaaagg agatccacga taacagcagc
     6061 ggaaaaatac gcagcacgtt gtcgatgaca gtattgagat cgctcgccca gcgcagggaa
     6121 agcagatagg agctgatcgc cagactggcc cctgccagca gcggccccag cgttaaaatc
     6181 atccagtaca cggcaaacga gtaaattttg ggtcgcgctc gtttactgcg ccagatggta
     6241 ttcaacgcgc tatcgatgga gtacatcaac aataacgccg tgacgatcag cccgcacgcc
     6301 ccgacggcgg tcattttgtt ggaattggcg acaaactgtt cgatatatcg ctggataaca
     6361 tcgccagtag caggcagaaa gttggcaaaa ataaagtgac gcaactgaat gctgacgtcg
     6421 gaaaacatgg gaaaagcggc gaaaagcgca aaaacaacgg caaccagcgg cactaatgag
     6481 agcaacgaca cataggcaag gttacctgcc agggttgtca tgttgtcctc atcaatgcgt
     6541 tgccagagta gttttagcca ggcccatagt ggacgggtac gatgcctggc tttgtcctga
     6601 atggttttta gcataacacc ttcgcgaaat agtccgggat ggtggtttta tctttcacca
     6661 gaatactagt aatgcctagc cgattagctc cttctatatt atcggcgtta tcgtcgaaaa
     6721 agaccgtatc gtctggtgaa aaaccttctg cccgcaaaac atgctgataa attcgtgctt
     6781 caggtttgcg catacccaag tcttgcgaca gatagatatg gtcagcagca tcacggattt
     6841 ccgggtattc ctccggccag aaggtagtat gcaggcggtt agtattggaa agcaccacca
     6901 cgcgatgccc ctgctcacgc agtttatgca tgatggcgat cacttccggt cgtagcgcaa
     6961 caaataccgc ctgccaaccg tgggagaact gctcatagct tagcggcagg gccatctcat
     7021 gacacagtgc ctctgcgaac gcttcgtcgc taatttcccc acgctcatgc tgatgaaacg
     7081 cctcgcccat gtggaaactc ttcttaagcg tagccagtgg aacacgcgtt aaatcgctcc
     7141 aggcccccag cacacggtta aagtcgatat cgacaatcac attacctaaa tcaaagatat
     7201 agagcatttt tgcctccttt cgcgccacaa gaaattaact gtagcgggaa aggatgggtt
     7261 tggctatgtg gcaataaggg taatcttgtg atgctgattg cgaaaaagca gagtaatttc
     7321 actggctttt tcgcaataga tgaatggtta agattcaggt gtaaattgcc aacgagtttc
     7381 gatgaccagc ggcttatctg gtgtcacaaa ttccggcgtt agatttattg cgttaggtgc
     7441 ctgagtcagc gggttaatac aggtggcatc gggctgttta tcaaatacca ccagactgtt
     7501 tgcagaagag gtcatggtca tcgcgagttt accaggccac agtaacttaa ccttcacccc
     7561 gtcataaaaa ccaaaacagt catcccaggg accaacttga ggagagatac gatttccagt
     7621 tggcagttca tcactacccg cttcttcttg ccagtccgca tcaaaaagca cctgcaacga
     7681 ttctgtattt tgcggagtca gctttttcgc aaaccacgga tgccagcctg cggaggccgg
     7741 gaatgtatcg gcatatgaat ggacttccag ttgcaaaacc agcgcatcgt tctccagcaa
     7801 aaaagtctga atcacttccc cttgccaggg ccacggtgaa gtcaggggca tacgtaaagt
     7861 cagggaatct gctgttttgt cgatgatttc ccacgttgag taacaagcca taccatgcaa
     7921 cgcatgtggt ggtttattgg cgggtaaaga ataacattgc ccaccagcat tcagcgtcgc
     7981 attccccagt cgccctgccc acggcaccat tgggaaacag ccatactgaa aagctctgcg
     8041 ctgcggctgc cattggcgta atacttcaga accaaatgcc tttaacgagg ttatcctggc
     8101 accatcatgc ggataaatct gcaggtgaat attgcctttt tccagcgtca ctaactctcc
     8161 tacaggccca ggccatggcg cgtcaaacgc ctgttgtagc gccaggtaat gctcgttttt
     8221 tcgttcagtt ttcatgagat tgttccctga tgtagcggta agaagcggtt tcttgttcat
     8281 cggttggctc aatcagccag acgcaaacaa aggaaagaac tgagacagca aataaaaaca
     8341 gagcgacata ccacggtttt cctcccccta gcgccagcaa acttgaggcg ataagggggc
     8401 ttagtccgcc aagaatcgcg gaaaattgat aagcaaaaga aaggccggta tatcgtactt
     8461 tggtaccgaa catgcgggtg aaaagtgttg gctgcacggc aaacatcatc gtcggaccta
     8521 agttgtagcc aaggatcata ctgcaccaga tgatgagcgt acttttgcta tccagtaata
     8581 agaagaaagg aaacgcgaac aggacacaaa accctgctcc cgacaaatac agactttttt
     8641 gacctatacg atctgataac catccaacca atggacaact gaaaataccg atcgccgagg
     8701 caatcaacat acccgtcagg ggaatatctc gcgacaatgc taattggctg gaaatataga
     8761 caataccaaa ggcgttaata atattagagg agacactttc cgccagcctc gcacccagtg
     8821 ccaataaaat atttcgtgga tgttttttga ataattcaat caacggagga acggactttt
     8881 ctttattatt cgtcgttttt tgcttttgaa aatccagcgt ttcttcggta tgcaggcgga
     8941 taaacagccc aacgatcaac atcaccgcag aaagccaaaa cggaatgcgc catccccagg
     9001 agagaaactg ctccgaagta agaaaatggt tacagagagc aaaaataccg gttgccagca
     9061 taatacccac agacgcagcc gtttgcggga gtgaacctaa aaatccgcgt cgggattcgg
     9121 gcgctgattc tatggtcatc aatgccgctc cgccgtactc gccaccaaga ccaaagccct
     9181 gaattaaacg tagcaccatt aatatgagcg gtgcccagat cccaatttcc tgatacgtcg
     9241 gaataaaacc aatcaaaaat gtggagcaac cgacaatagc caacgtccag ataagcgtta
     9301 tttttcgccc tattttatcg ccaaaatgac caaagacgat gccacctaaa ggacgagtca
     9361 gaaaaccgac accaaaggtc gcaaaggaag ctataagacc tataaaagga tcgctgtctg
     9421 gataaaacag cggtgcaaat accagtcctg ctgccgtgcc aaaaataaag aagtcatacc
     9481 attccattaa cgcgcctgcg aaactgccca taacgacacg tctcatggct ttaccggaaa
     9541 gcccttcacg cggtgcgggt aacttttcag acataatttt cctctcctgg taggcgagaa
     9601 atctgggata cgaaccacta aacgtgggca gtttgaatta atgcgcatcg gcttaaaccg
     9661 atgcgcatta aattatttct tcaattcagc cagaacctct gcgtcctcag catcaacatt
     9721 tgcacccagt ggttcccaat taatcaatac acaggtcagg aatcccagga atggcacgat
     9781 tgccaaccag taaaacgctt cggttttcaa cgcaccccac agcatcggcc agaaaatgag
     9841 tcctgcaatt gcccctgtgc gcataatagc gcgggcaaat ccgaccccag tagggcgaat
     9901 agcgggagga taagagagtg tggcaatggt catgcccagc ccaccaggac ccgctgaatg
     9961 gaagaaaata attgatccca ataaccctaa agacagccag ggattagtcg ttgccagtgc
    10021 gcctaacgac agcaatgcta aggtcacaac agcaaatcca tacatcgact gtcggcgagt
    10081 acccagtcgt tggagaataa acgagccgat catcccgcct gtcaccccac aaagggcatt
    10141 cacgacggca gaaccggtca acgcgccagt aagcccgcca cttattattc ccgccaacgt
    10201 aagaggaaga taaacaccta cggcgttata ttgccacgcc tgcatggttg ccacgacaca
    10261 gccaagaatg gtgcgtttgc ggtaacgatc attaaataag atgccatatc caccactgta
    10321 tttattctct gctttttccg agaatttcgc ttctgttgta cccgatgccg caacgcgagc
    10381 ctgaacacca taacgttttc ccagaatgtc gcacgcttcc tggtaacgcc cgacgcgtgc
    10441 ggcccacatt gcggattcac caataaagaa gtaacgcaaa atcatgaaga tgactgcaaa
    10501 aatagctccg atgaatattc cgtaacgcca caattgttct tcagcgatac ccgacagaag
    10561 cagcggcaaa agcaccaaat aaacaacggt tgtcgaaaca taccaggcca tttgccagag
    10621 gttgaccgac gttccggttt tcttcgacgt tgaaccacga agctctgcca cggcattggt
    10681 tgccaaaggg aagtcgatgc ctaaaccaaa gcccatgatg acgcggcaca ccagcaccca
    10741 ccagatactg ggagcaatag ctaccgctgc agcaccgatg gtgcacagcc ccatgccaat
    10801 aataaatgcc cgcttttgcc caaagcggtt tattactcgg ttcgctaata aaccgccaat
    10861 taacgcggcg attaatactg atgcattgac ggttgcagca agacccggcg aaatgccgaa
    10921 ttgagcggca atgtatttat taccaaaccc caccatcgcc gcctggtagg catcaatcaa
    10981 tatgccgccc aaagcaataa aaataacgcc gatactggtg ttgattgcag agttcttatt
    11041 aacaatatca attacgtcct gtggccgact aattgaataa gttgcaggac tggtgatttg
    11101 actcatcgca gtgtcctttt taattgttgt agggtggcgc tgacgtgacg cagcgccaga
    11161 cagagattta gaaaatcatt ccggcgcaaa ttgcagcatg acctttatgg agtcattttg
    11221 ctgcgcgcgt tcgaatgccg ccgctgcatc ctcaatggca aataaatcgg taaccagttc
    11281 actggtatca aaccgcccat ccgccagcca ttcgataaca gcatcgaaat cttcagggat
    11341 gtacatgcca gagttgagca agtcacgctc gaaacgttgc atcatcggta atggtatttc
    11401 acgcggccca cttggtacgc ccatgcacac gacggtgcct ccggcatata cacgggtaca
    11461 tgcatcgtta agcgtggcct gcgctgcaac gacatcaatc gcccccgtaa atcgcacatc
    11521 tgcggccagc tcacctggtg cccaaacttc tgctgcgccc agttttaacg ccagcgcgcg
    11581 tttggcagcg tcaggttcaa tcacggtaat cttacctgcc cccataatgc gcagtgcctg
    11641 cacgatggat aagcctatcg ttccggcacc aatcaccagt acgctttcca gagaagcttt
    11701 cggcattcgg ttaacgcagt gacgagcaca agccgccggt tcggcaaagg ccaacacttt
    11761 tagcggtaaa gaggctggtg cgacatggca attacgcgca ggaacaatgt gttgtgagcg
    11821 agcaaagccc ggtgcgcgaa aaccagcaac ctgcggtggt tcacaaagat taaaacgtcc
    11881 tgctttgcag gctcggcatt ccatgcaagc catgatggga tcgaccacaa catgatcgcc
    11941 cggctgtaca tttttaacgt cgctgcccac ttccgtaacg cgcgctgcaa tttcatgacc
    12001 ggggacgaca ggcggtttgg caaacggatg accgcctttc agaacatgca gatccgaacc
    12061 gcatatcccg tagaacacgg gcgcaatccg tacttcgtgc ggtttaagtt gctggtgtgg
    12121 tacttcaaca tattgagtgg tgactttccc aatatctgaa aataaaacct gggtaatttt
    12181 atccattgtt attctccaga atcgatatcc ataggggatt agcgttgcgc gataccttca
    12241 tcgacaattt cagccagccg ttgcaagcgt ggaacggaga catcgcgcag catggtttgt
    12301 ggatcttgtg caccaacaac cgacgcccaa accgctcgtc cagccaggaa gcccgacgca
    12361 ccacctttca tggcaatact tactgcacgg ccaaaaatat cggcatcaac gccagaagaa
    12421 agaattaccc acggcatctt catctgatcg ttaagttgct gacaggcagc aagtaaggtt
    12481 ttttcatcgc ctttgccccc taatggcatc tcggctttgt aaagatcagc ctctgttcca
    12541 ccaagctctg cggcggcggc aacaatggcg ctttcacgat caaagtccca accgcgacga
    12601 ggtggacgca ccacaggttc aataatgcta accagcccgg cactacggca gcgacgaaca
    12661 aatttatcaa ccattgccag acgttcctct gcgggttcat cttcacgcca gagtacaagt
    12721 aatttcattg ccttagcccc catttcacgg gctttatgcg ggtcgacgga catatctatt
    12781 tcaacgctat caaccgggat gccattacct gggataaaaa gatcggcagc gacaatcagg
    12841 ccgcaagaat tagccacagc gccctgctcg actatttgtt caagacaaaa ttgtttatcc
    12901 gccagaacgg cagaagcata aggagaaagg attcgggtcg cggcaacttt aaaatcggtg
    12961 agtacactgt cggcgatggg ttttggctgc cctgctgccg caaacatcag gcgcatggcc
    13021 tcacgctgat cgacagctaa catggcgaat ccaccacctg ggcgggagat atctttcagc
    13081 gtaaatgggg tgaagtggga tgacatagaa actcctgtta atagataaaa ttaaagacca
    13141 gcctgctggc gaacctgatt tagcagggcg ctccagtcct gccgcccttt gccgtcttga
    13201 cttgctgcgg cgtaataact ttctgctgca atccccatat tgagcggcgc ccccgttttc
    13261 cgagcgacgt caactgcaat acgcagatct ttcaatgcca ggtccaccat gaaggcggga
    13321 gaaagatcgc ctttcagcac tttgccaggc caggtggtcg taaaatgtcc tttccctgct
    13381 gccgtaccac tcatcacctt aattgcgaca tcaagattta atcccagtga ctcacataac
    13441 acagcggctt cggaggacag cgcattaagc gcaatgctca tatagttgtt aattagcttc
    13501 acgcggatcc ccattcctgg gccaccagcc tcgaccagct cattacccat gcacatgaga
    13561 atcgggcgtg cacgcgcaat ctgctcatca gtgccgcccg ctaaaatcag caatgtgcca
    13621 tcaatcgcat tcactgacgt tctgcccacg ggggcgtcca tcatattgat gcctttttct
    13681 tgtaattccc gtattaatgc atcggtctgt aagggatgaa tagtcgacat atcaatcact
    13741 aacgcgtcag atgaaacagt ttcacagacg cctttttccc ccaacagcac ctgtcgaaca
    13801 atgtccccat tgggaagcat agtgatgata aattcagcgc ttgctgccgc ttccgctggg
    13861 gtttgtgccg cagtggcccc ctgcgtaact agcgcatcga cggcctgtgt attgacatca
    13921 aatacctgta atgaatgccc tttttgcaat agattgttag ccattgggct acccatctgc
    13981 cccagcccga gaaatgcaat ggttgccatg aatactctcc tgtctgacat tgacaaaata
    14041 atgacaattg aaaattcgtt ttcgtctgtt tttgagcata tttgtaattt atgttcaaaa
    14101 acacgacacg catcactaat ttgatcattt gtgtcattta aattgaccaa agacgacaaa
    14161 attaaacagg acaagacaaa tatgaccaga attgcatgcg tgggtatcac agttcaggac
    14221 agaatttatt ctttgcccac tctgccggag ggtggcggga aatatcaggc aaatcattat
    14281 cttgagattg gtggcggccc ggcagcaaca gccgctgttg caatcgcaaa gcttggcgtg
    14341 gaggttgatt tcatcggtcg cgtcggcgat gacagttgtg gaaatacctt acttgcagaa
    14401 cttgagggtt ggggcgtcaa taccgcattt tgccgccgat atcctaacgc ccgttcgtcg
    14461 caatcagcga tcctcgttga tcagcatggc gaacggatta tcgttaatta tccaagtcct
    14521 gatctcggta ctgatgccga atggttagaa gcgatcgatt tctctcgtta tgatctgatt
    14581 ctggccgatg ttcgctggca tagcggtact gaaaaagcat tctcgctagc gcgccttgcg
    14641 ggtgtgacaa cgcttttaga cgccgatatg acaccgcagg atatttctcc acttgtcgcg
    14701 cttgccgatc acgccgtgtt ctcaacacca gggctgaaac gcatgactgg cctgcagtca
    14761 cctgaagaag gtttgttcca ggcaacgaca caaacagcag gtaaagtgta tgttacgctg
    14821 ggttctgaag gatcgttgtg gattgaagat ggtcatttgt gtcaacagga ggcattttct
    14881 gtcaatgtgg ttgataccac tggagcaggc gatgtttttc acggcgcact cgcggtagcg
    14941 ttggcagaaa aaatgccaac aaaagaggct attcgttttg ccagtgcggt tgccgcgatg
    15001 aaatgtaccc agcctggcgg tcgggccggc attcctaatc gtgagcaaac cgaatcattt
    15061 ttgtcacttt atgcgtaaaa tggtaaacat ctaccgagga ggggcaaggg agtattcatg
    15121 agtatcatcg aagtgacagg taatccacgc catgaccaac tcgttcatct aatcgcagaa
    15181 cgcggttata tgaatattga agaactggca caactgctgg atgtttcaac gcaaaccgtg
    15241 cgccgggata tccgaaaact cagtgagcag ggcttgatca cccgtcatca tggaggggcc
    15301 gggcgcgtct ccagcgtcat gaataccgct tttgagcaac gggaactttc gctcaccgcc
    15361 gagaaacggg cgatcgctga ggcagtcgcc gattaccttc ccgaacgctg taccgtcttt
    15421 atcaccatcg gtacaaccgt agaagccgtt gccagggcat tactcaaccg gcgtgattta
    15481 cgcattatca ctaatagcct gcgtgtggca cagattcttt ataagaatca ggatattgaa
    15541 gtgatggtgc cgggaggcac tttacgcgct cataacggtg ggattatcgg cccaggagcc
    15601 gtggatttta ttgaaggctt ccgcgcagat tatttaatca ccagtatagg tgccattgaa
    15661 catgacggca ccctactgga atttgatgtc aatgaagcgt tagtcgcgag aacgatgatt
    15721 aaacatgcgc ggaatacatt gttagtggcc gatcatacga agtttaccgc gtctgctgcc
    15781 gtttcaattg gcaatgcacg gaatgtcagg gcttttttta ctgatgcccc gcctcccaat
    15841 tctttctgcc agttgttaag tgaagagaat gttgaactgg tggttgccga gcaagaagta
    15901 tcctgaaatt gaaacttcgg aaaatccgct gggaatttca gcggattttg ttttccataa
    15961 gccaaaaaaa aacctgccat cgctggcagg ttttttatga ctgaaaaacg aaattaatcg
    16021 tctttcggtg cgcggttagc gcgacgacga tcgttttccg tcaggtgacg tttacgaata
    16081 cggatagagg tcggagtcac ttctaccagt tcgtcatcat cgatgaactc cagagcttgt
    16141 tccagagtca tgcggatagg cggaaccaga acaacggctt cgtcagtacc ggaagcacgc
    16201 atgttggtca gtttcttacc ggtcaggcag tttacagtca ggtcgttaga gcggctgtga
    16261 ataccgataa tctgaccttc gtaaacttct gcaccgtgac cgaggaacag cttaccgcgg
    16321 tcctgcagac cgaacagtgc gaacgcgacc gctttaccct gaccgttaga gatcagtacg
    16381 ccgttctgac gctggcccac ttcacccgga cgtacgtcgt cgtagtggct gaaggtggag
    16441 tacagcagac cagtaccgga agtcatggtc atgaactcag aacggaagcc aatcagaccg
    16501 cggcttggga tcacgtagtc gagacgtaca cggcctttac cgtctggatt catgtttttc
    16561 aggtcgcctt tacgttcgcc cagcgcctgc attacagaac cctgatgctg ttcttcaacg
    16621 tccagagtca cgttttcata cggctcttgt ttacgaccgt cgatttcacg gaagataact
    16681 ttcggacggg ataccgccag ttcgaaacct tcacgacgca tgttttcgat cagaacagac
    16741 aggtgcagtt cgccacgacc agaaacgcgg aacgcatcgg cgtcttcggt ttcttctacg
    16801 cgcagcgcaa cgttgtgtac cagttctttg ttcagacgat ccaggatctg acgagacgtt
    16861 acgaacttac cttctttacc gcagaacggc gaggtgttaa cgcagaagaa catagaaacg
    16921 gtcggctcat caacggagag tgccggcagc gcttcaacgt tttgcgtgtc gcaaacggtg
    16981 tcagaaatgt tcagttcgcc caggcccgtg atcgccacga tatcgccagc ttccgccaga
    17041 tcggtttcga tacgttccag accgaggtgg cccagcactt taccgacttt cgcgttgcgg
    17101 gttttgcctt cgctatcgat gatagtaacc tgttggttcg gcttcacttt accgcgcttg
    17161 atgcggccaa tgccgataac gccaacatag ctgttgtaat cgagctgaga aatctgcatc
    17221 tggaacggac cgtcaaggtc aacgtccggc gcaggaacgt ggtcaacaat cgcctggtac
    17281 agcggggtca tgtcttccgc catatcttcg tggtccagac ccgcgatacc gttcagcgca
    17341 gaagcgtaaa cgatcgggaa gtccagctgc tcgtcggtcg cgtcgaggtt aacgaacaga
    17401 tcgaatacct gatccacaac ccaatcagga cgcgcgccag ggcggtcaac tttgttgata
    17461 acaacaatcg gcttcaggcc gtaagcaaac gcttttttgg ttacgaagcg cgtttgcggc
    17521 atcgggccgt caaatgcgtc aaccaccagc agcactgagt ctaccatgga cattacacgt
    17581 tcaacttcac caccgaagtc ggcgtgcccc ggggtatcaa cgatgttgat acggtaatca
    17641 ttccatttga tagcggtgtt tttcgcgagg atggtaatcc cacgctcttt ctccaaatcg
    17701 ttggagtcca tcacgcgctc ttgggtttcg gcacgagagt cgaacgtacc ggattgttgg
    17761 agcagcttgt ctaccagggt ggttttacca tggtctacgt gcgcgatgat ggcgatatta
    17821 cgcaattttt cgatcacaac tttgcctcag gcattagaaa tagcgcgtta ttgtacacgg
    17881 attaatcgca ctacaaaaca ggatcacaaa catcctccgc aaacaagtat tgcagagtcc
    17941 ctttgtgatc gctttcacgg agcataaaaa gggttatcca aaggtcattg caccaatatg
    18001 gtgcttaatg ttcccattga agcactatat tggtgcaaca ttcacatcat ggtgcagccc
    18061 ttttgcacga tgttaagcat gataacgcct tttaggggca atttaaaagt tggcacagtt
    18121 ttcgctttat cttttttacg gcgacacggc ccatttaatt gcagatttcg ttaccacgac
    18181 gacaatgacc aatccaggag agttaaagta tgtccgctga acacgtactg acgatgctga
    18241 acgagcacga agtgaagttt gttgacttgc gcttcaccga taccaaaggt aaagaacagc
    18301 acgtcactat ccctgctcat caggtgaatg ccgaattctt cgaagaaggc aaaatgtttg
    18361 acggctcctc gattggcggc tggaaaggca ttaacgaatc cgacatggtg ctgatgccag
    18421 acgcatccac cgcagtgatt gacccgttct tcgccgattc taccctgatt atccgttgcg
    18481 acatccttga acctggcacc ctgcaaggct atgaccgtga cccgcgctct attgcgaagc
    18541 gcgctgaaga ttacctgcgt tctactggca ttgccgacac cgtactgttc gggccagaac
    18601 ctgaattctt cctgttcgat gacatccgtt tcggatcgtc tatctccggt tcccacgttg
    18661 ctatcgatga tatcgaaggt gcatggaact cctccaccca atatgaaggt ggtaacaaag
    18721 gtcaccgtcc ggcagtgaaa ggcggttact tcccggttcc gccggtagac tcagctcagg
    18781 atatccgttc tgaaatgtgc ctggtgatgg aacagatggg tctggtggtt gaagctcatc
    18841 accacgaagt cgctaccgca ggtcagaacg aagtggctac ccgcttcaat accatgacca
    18901 aaaaagctga cgaaattcag atctacaaat atgtcgtgca caacgtggcg caccgtttcg
    18961 gtaagaccgc gacctttatg ccaaaaccga tgttcggtga taacggttcc ggtatgcact
    19021 gccacatgtc gctgtctaaa aacggcgtca acctgtttgc tggcgacaaa tacgcaggtc
    19081 tgtctgaaca ggcgctgtac tacattggcg gcgtaatcaa acacgctaaa gcgattaacg
    19141 ccctggcaaa cccgaccacc aactcttaca agcgtctggt cccgggctac gaagcaccgg
    19201 taatgctggc ttactctgcg cgtaaccgtt ctgcgtctat ccgtattccg gtggtttctt
    19261 ctccgaaagc acgtcgtatc gaagtacgtt tcccggaccc ggcggctaac ccgtacctgt
    19321 gctttgctgc cctgctgatg gccggtcttg atggcatcaa gaacaagatc catccgggcg
    19381 aagccatgga caaaaacctg tatgacctgc cgccagaaga agcgaaagag atcccacagg
    19441 ttgcaggctc tctggaagaa gcactgaacg aactggatct ggatcgcgag ttcctgaaag
    19501 ccggtggcgt gttcacggat gaagcgatcg atgcgtacat cgctctgcgt cgcgaagaag
    19561 atgaccgcgt gcgtatgact ccgcatccgg tagagtttga gctgtactac agcgtctaat
    19621 agttgaagtt gtactacccg gcgcaacaac gccgggattt agttgccgtg gaaactttca
    19681 gcccatctct gcatgggctt ttttctccgt caattctctg atgcttcgcg ctttttatcc
    19741 gtaaaaagct ataatgcact aaaatggtgc aacctgttca ggagactgct ttatggcaac
    19801 aggcacgcag cccgatgctg ggcagatcct taactcgctg attaacagta ttttgttaat
    19861 cgatgacaac ctggcgatcc attacgccaa ccccgccgcg caacaactgc tcgcccaaag
    19921 ctcccgcaaa ttgtttggta caccgttacc ggaactgttg agctacttct cattaaatat
    19981 cgagctgatg caagaaagtc tggaggcggg gcaaggtttt accgataacg aagtgacgct
    20041 ggtcatcgac gggcgctcgc atatcctttc tgtgacggct cagcgtatgc cggacggcat
    20101 gatcctgctg gagatggcac cgatggataa ccagcgccgc ttaagtcagg aacagctaca
    20161 gcacgcccag caggttgctg cccgtgattt agtgcgcggc ctggcacatg agattaaaaa
    20221 tccgcttggc ggtttacgtg gcgcggcgca gctgctcagc aaagcattac ctgatccgtc
    20281 actactcgaa tataccaaag tgattatcga acaggcggac cggctgcgaa atctggtcga
    20341 ccgtctgttg gggccgcagc tgcccggtac gcgcattacc gaaagtattc acaaagtggc
    20401 tgaacgcgtg gtgacgctgg tgtcgatgga actgccgaac aacgtgcggt tgattcggga
    20461 ttacgacccc agcctgccgg aactggcgca cgacccggat caaattgaac aggtcttgct
    20521 gaatattgtg cgcaatgcgc tacaggcgct ggggccggag ggtggtgaaa tcattctacg
    20581 tacccgcaca gcgtttcaac tgaccttaca cggcgagcgc tatcggctgg cggcgcggat
    20641 tgatgtggaa gataacgggc cgggcattcc gcctcatttg caggatacgc tgttttaccc
    20701 gatggtcagc ggccgcgaag gtggcaccgg gcttggctta tccatcgccc gtaatttgat
    20761 tgatcagcat tcaggcaaaa ttgaatttac cagttggcca ggtcataccg agttctcggt
    20821 ttacctgcct atcaggaaat aaaggtgacg tttatgcaac gagggatagt ctgggtagtc
    20881 gatgacgata gttccatccg ttgggtgctt gaacgtgcgc tcgctggagc gggtttaacc
    20941 tgtacgacat ttgagaacgg cgcggaagta ctggaggcgc tggcgagcaa aacgccggat
    21001 gtgctgcttt cagatatccg tatgccggga atggacgggc tggcgctgct caagcagatt
    21061 aaacagcgcc atccgatgct tccggtcatc attatgaccg cacattccga tctggatgct
    21121 gccgtcagcg cctatcaaca aggggcattt gattatctgc ccaaaccgtt tgatatcgac
    21181 gaagccgtgg cgctggttga gcgcgccatc agtcattacc aggaacagca gcagccgcgt
    21241 aatgttcagc ttaacggccc aacgaccgat atcatcggtg aagcgccagc catgcaggac
    21301 gtgttccgga ttatcggtcg gctttcgcgt tcttctatta gcgtgctgat taacggcgaa
    21361 tccggcaccg gtaaagaact ggtcgctcat gccctgcatc gccacagtcc gcgagccaaa
    21421 gcgccgttta tcgcgctcaa tatggcggct atcccgaagg atttgatcga atccgaactg
    21481 tttggtcacg agaaaggcgc atttaccggc gcgaatacca ttcgtcaggg gcgttttgaa
    21541 caggctgatg gcggcacgtt atttctcgat gaaattggcg atatgccgct agatgtgcag
    21601 acgcgtttgc tgcgcgtgct ggcagacggt cagttttatc gcgttggcgg ctatgcgccg
    21661 gtgaaagtag atgtgcggat tatcgctgcc actcaccaga atcttgaaca gcgggtgcag
    21721 gaaggcaagt tccgtgagga tctgttccac cgcctgaacg tcatccgcgt tcatctgccg
    21781 ccgctgcgcg aacgtcggga agatattccc cgtctggcgc gccatttttt acaggttgcc
    21841 gcgcgagagc tgggcgtaga agcgaagttg ctgcatccgg aaaccgaagc cgcgctgacg
    21901 cgtctggcgt ggccaggcaa cgtgcgccag ctggaaaaca cctgtcgctg gctaacggtg
    21961 atggctgccg ggcaggaagt gttgattcag gatttgcctg gcgaactgtt tgaatcaaac
    22021 gtaccggaaa gcacttcaca catgcagccg gacagttggg caacgctgtt agcacagtgg
    22081 gcagacagag cgctgcgttc cggtcatcaa aacctgcttt ccgaagcaca gccagagctg
    22141 gaacggacgt tactgaccac cgcgctgcga catacgcagg ggcataaaca ggaagcggcg
    22201 cggctacttg gctggggtcg caacaccctg acgcgtaagt taaaagagct ggggatggag
    22261 tgattcacgg cttgtgtgta aagattgatt attgagcgca aattgctggt attttgcgct
    22321 ttactgttcc gataagttca gtatgatctt gcccggaaaa cggggagagt cattatgctg
    22381 gaatcaataa ttaatctggt atcgagtggc gcagttgaca gccacacacc gcaaactgct
    22441 gttgctgccg tgctgtgtgc cgcgatgata gggctgttta gctgaagctc gttgtttacg
    22501 ccggatgcgg agaaagtcgt aggcctgata agacgcaacc agcgtcgcat caggcgttga
    22561 ttgccggatg cggcgtaaac gccttatccg gcctacaaaa gcaataattt caacagattt
    22621 tgcaggcctg ataagcgtag cgcatcaggc aatcttgttc tcagcacatt gatggcgctt
    22681 tcgttttcta ctttgtaaac gaagcgccat tcacaattta aatcacccga gagaactgct
    22741 gcatccgcgc tttctggcgc agataggtat caaagcacat gcaaatgttg cggatcagca
    22801 agcgaccttt cgccgtcacc tgtattccct tctcatccac atccaccagc ccatcttttg
    22861 ctaacggggc gagcagcttg agatcttccg caaagtaatc agcgaagagc aaatcccact
    22921 gttgctcaat aggggcgtaa tccagacgga agttgcagat gagcgactta atcacatcgc
    22981 ggcgaataca gtcatcacgc gttagcgcaa taccacgcca cagcgcattg ccttgttcat
    23041 ccacttgctg atagtactgc ttcaactctt tctggttctg cgcgtagcag tcgccaatca
    23101 tgctgatggc ggaaacgccc atccccagca gatcggtatc gccctgagtg gtgtagccct
    23161 ggaagttacg atgcagcacg ccttcacgct gggccaccgc cagctcgtca tccggacggg
    23221 caaagtgatc cataccgata aactgatagc ccgattgtgt caggaaggcg atggtttcct
    23281 gcaggatatc gagtttttgc tgcggactcg gcaggtcagc atctttgatt ttgcgctggg
    23341 cggcaaaaat ggtcggcaaa tgcgcgtagt taaagacgct cagacggtca gggttcagtt
    23401 ccgccacacg cttcagggta aaggcgaaac tctccggcgt ctgtttcggc aggccgtaaa
    23461 tcaggtcaat gttggtggag gtaaagccaa tctcacgcgc atggttaagc agtgcaaaga
    23521 tgaactcttc atcctgctcg cggttaacca gacgttgcac ttctttgttg aagtcctgca
    23581 cgcccatgct cagccgatta aagccttcgg cgcgtaaatg atcgagtaca tccagttcga
    23641 tttcccgcgg atcgacttcg atcgagatct ccgcatcggc attgaactgg aagttttcgc
    23701 gcagcagctt catcagacgg ctgatttgcg ctttattcag atacgtcggc gttccgccgc
    23761 cccagtgcaa ttggctgacg tgacgcccgg cgaacagcgg tgcacgatgg acgatttctt
    23821 gctccagcgc gtccagatac tgatcggcct tgtgctgctg gcgagtaaca atcttattgc
    23881 aaccgcagaa gtaacaaagc ttatggcaga acggaatatg tacatagaga gataatggac
    23941 gctcaggata gcgcgccaca gcttgtaaaa acgcctgttc gccgaagtct tctgaaaact
    24001 ccagcgcggt cgggtacgag gtgtatcgtg gcccggaata gttatatttc tggatcaggg
    24061 ccagatccca gtcgatttgc tgtacagaca tgctcactcc ttccgatggc gtctctggcg
    24121 gctacggcgt accggcggat gcccgtttcg agtcatcagc cggttgcgca gccacttttg
    24181 tcgccgcgac aaccgctgta gtttaacgaa taaccacacc agataacata taaccggaag
    24241 ggttatcagc agaacgggaa ggcccacggc ggcaatccgt tagttgcccc gcagcagacg
    24301 catcatgtct tcttgcttct cgtcttcttc ctcttcttcg tcatcgtcat aagagaggcc
    24361 gagtttctgc atcaactcat caatacgatc cagtttggca tccacccagg attgctcttc
    24421 ggcgctcagg gtttcgcctg cttccagacg ttccagcagc gcatccagac gctcatccgt
    24481 ttccagtaac tccaactccg cctgcggtga aagcataggt ttctcactct tcggtttgtg
    24541 ctgtttggtg actttttcag tcacgcccaa tggaataggg gttttactgc caatacgtgg
    24601 atcttttggt gcgttctgac ctttgctgcc tgacgtggtg ttaccgcccg ctgcgcggct
    24661 gcccggcgca tgaccacgac gttttttctg acgcttacgg tcacgagctt cctgatccag
    24721 ctcctcgcgt gtttttcgac gcgcttttgc atgacctttg ctgcgtgagt ttgaagatga
    24781 tggtttcata atggttcgtc ttttagccgt tttattcagt atagatttgc ggcggaatct
    24841 aacagaaagc aagcaaagaa aaaaggcgac agattactct gtcgcctttt ttcctgactc
    24901 ataaccctta acgggtctta caatccttgc aggccgccaa cacaccctgt ttttccatta
    24961 gccggaacaa tccgtgttga ttccatttcc atttaattac gtctccggac gtttatcttc
    25021 ctgacaatcc tctgtcttcg cctcctggcg ctcctgaccc tcatcctgag tcattgttcc
    25081 tgttagcgtc ctcgctctat gggtgctact ttacgccttt gctttaaata aacaatcaac
    25141 cgccatcagt atttgcacat tttcagagtt ttatataaaa gcaattcact gatttatata
    25201 gcttatttga catacgtcgc agaattttct ctgctatttc gcataaagac tatcggcaat
    25261 gtctcacaaa gcatatggct tttacttaca acgctcacgc cgaaaaatcc gccttttatt
    25321 atggttcagg tataatcgcc gcaaagcttt gactgatgga gacgaccgct ttgactaatt
    25381 tgaattatca acagacgcat tttgtgatga gtgcgcctga tattcgccac ctaccttccg
    25441 ataccggaat tgaagtggct tttgcaggcc gttccaacgc aggtaaatcc agcgcgctga
    25501 acacgctgac taaccagaaa agcctggctc gtacctcaaa aaccccaggg cgcacccagc
    25561 ttatcaacct gtttgaagtg gctgacggca agcgtctggt tgacttgcct gggtacggtt
    25621 atgcggaagt cccggaagag atgaagcgca aatggcagcg cgcgctcggc gagtacctcg
    25681 aaaaacgtca gagcctgcaa ggtctggtgg tgctaatgga tattcgccat ccgctgaaag
    25741 atttggatca gcagatgatt gagtgggcgg tagacagcaa tatcgccgtg ctggtactgc
    25801 tgaccaaagc ggacaaactg gcaagcggcg cacgtaaagc gcaattgaat atggtgcgtg
    25861 aagcggtgct ggcgtttaac ggtgatgtgc aggttgaaac gttttcttcg ctgaagaaac
    25921 aaggcgtgga caagctgcgg cagaaactgg atacctggtt tagcgagatg cagcctgtag
    25981 aagaaacgca ggacggcgaa taattttctt gccttaatgc ttgtgccgga tgtggcgtat
    26041 ccggcccgta aattcaatag attacaattc taccgttggc ctgataaaca gggcgcatca
    26101 ggcattacgg atcttttctt tcgcccaata aaaaacgccc cagtcattac tgactggggc
    26161 ggctaaaata ttcagccaaa tccgattacg tgaagtaaaa ggtctgaaag atagaacatc
    26221 ttacctctgt accctacgcg actaacttta ctcttttttg ttcagttcag aaagcatttt
    26281 ttgtaatttt ttttcagttg ttgcatagga atttctaata gccatcacaa aacgtgacag
    26341 cttatgttgc ttacttacga aaaaagggca tgttcaggcg aatcttagtg cgcctgatcc
    26401 cagttttcgc cactccccac ttccaccagc aacggcacat ccagacgggt acagttttcc
    26461 atcagttgat gaatctgctt cgcgacggca tcgacatcat ctttatggac ttcaaatacc
    26521 agttcatcgt gtacctgcat gatcatacgc acacgcggtt gctcagcctg tagccacgca
    26581 tcaacggcaa tcatcgcccg tttgataatg tcggcggcgg ttccctgcat tggcgcgtta
    26641 atggctgcac gttcagccgc tgcacgacga gccccattgc tggatttgat atccggcaga
    26701 tacagacggc gtccgtccag cgtttcaacg tagccctgct ctttcgcctg agcacgggtg
    26761 cgttccatat actccagcac gccagggtag cgttcgaagt aaaggtccat gtacttctgc
    26821 gcttctttac gtggaatgtt caattgccgc gccagaccga aagcactcat gccataaatc
    26881 agaccaaagt tgatcgcttt cgcgctacga cgttgctcgc tggtgacggt ttccagtggc
    26941 aaaccaaaca cttctgccgc cgttgcacgg tggatatctt ttccttccgc gaatgcggtc
    27001 agcaagcctt tgtcacgcga gagatgcgcc ataatgcgca gttcaatctg cgagtagtcc
    27061 gctgagacaa tcacataatc ctctggcgca ataaacgcct ggcggatacg gcgaccttct
    27121 tcgttacgca ccggaatgtt ttgcaggtta ggatcggttg acgataaacg tcccgttgcg
    27181 gttactgcct ggtgataaga ggtatgtaca cgcccggttt tcgggttgat catcaacggc
    27241 agcttgtcgg tgtaggtcga tttcagcttc gccagaccac gatattccag aatcactttt
    27301 ggcaacggat agtccagcgc cagttcttcc agtacctctt ccgacgttga cggcgcgcca
    27361 cccggagttt tcttcagcgg tttaatgccc tgtttttcaa acagaatggt ttgtaactgc
    27421 ttggtggaag aaaggttaaa ttcttcacct gcaatttcat gcgctttctt ttccagctca
    27481 gccagacgca aggtgagctc ttcagagtga ttgtgcagca ctttcggatc gatcttcaca
    27541 ccgttacgtt caatgcgtga aagcaccggc accagcggca tttcgatatt ctcgaagacg
    27601 ttcaacggcc ctttgtgttt ttgcagatcc ggccacattt tcagatgcaa ctgcaaggtg
    27661 acatctgcat cttcggcggc gtaacgtccg gcttcttcga gggcaatctg gttaaaggtc
    27721 agttgatttt ttcctttacc agcaatctct tcaaaagtga tggttttgtg cttcaaccaa
    27781 cgttccgcga ggctgtccat atcgtgacgc ccggcaacgc tattgagaat gtaggactcc
    27841 agcatggtat caaacgcaat cccacgcagc tcaatgccgt aattcgccag aataccgcga
    27901 tcgtatttca ggttttgccc gaccttcagc gccttttcat cttccagcag cggttttagc
    27961 aactcgagtg cacgctcgcg agagatttga tcgggcgcat caagataatc atgagcaacc
    28021 ggaatatatg ccgctacgcc tggctcgata gcaaaagaaa gcccgaccag gttagcagag
    28081 atgttatcaa ggctgtcggt ttcggtatca aatgcaaata ccggcgcttt ttccagcttc
    28141 gcaatccacg ctttcagtgt ttcttcatca aggatggtga cgtagttgtc ataagaaatc
    28201 accgttgccg tcacttctgg cgcttcgtct gcaacactgg tttcctgcgg cctggctgcg
    28261 ggtttcgccc ctttagcctg tagccatttg cccgcttcga catcagcagt ccagcgtttg
    28321 aactcatact ttttgaacag ccctaacaac tcttccgccg ccggtggctg cacttccagt
    28381 tgttcacagg tcagctccag ttcaacgtcg gttttaatcg tcgccagctg gtatgagaga
    28441 taagcaactt ctttgttttg ctcgagcttg gctgccattg ttttcgcgcc acggaagctc
    28501 aacccagcaa ttttttctgg ctcggcatac agcgtatcca gcccgccaag accttgcagc
    28561 aatgcctgcg cggttttttc accgacgccc ggtacgccag ggatgttatc ggaggagtca
    28621 cccatcagcg ccaggaaatc gatgatcagt tctggcggca cgccgtactt attcaccacc
    28681 tcttccggtc cgaggatggt attcgtcatg gtgttgataa gcgtaatatt tggcgtcacc
    28741 agctgcgcca tatctttatc gccagtgctg atcagcaccg gacgcccggc tttttcggct
    28801 tcgcgcgcca gagtaccgat aacgtcgtcc gcttctacgc cagaaaccgc cagcagcggc
    28861 agtcccatcg ctttaaccat cgcgtgcaga ggttcgattt gtgctcgcag atcgtccggc
    28921 attggcgggc gatgtgattt gtaatgttca aacagttcat cacgaaaggt ttttcccttg
    28981 gcgtcaaaga ccaccgctgc atgcgtcggt ttatattgca tgatcagact gcgcagcatg
    29041 ttgaggacac catacatcgc accggtcggc tcgcctgcgc tgttagtcag cgggggaaac
    29101 gcgtgatatg cgcgataaag ataagatgaa ccatctacaa ggataagtgg attttggggg
    29161 atctgaacca taatgtccgt gcctgtttat cagattatgg gtaaaggatg ccacagacag
    29221 gatgaaaaca tgagtttttc accgcttttc gtgaaaatct tttgtagatc ttctggatcg
    29281 ctcgcaaatc gtcatgtgga taactttgtg cataaattat ttacatcgct tttaatttat
    29341 tatcatgctt tttacagcat gatgtttgtc tttgattttc atgcagttaa aaataaagcc
    29401 atcccttgag ataatgggat tttttctaat gtggatagat atgaattatt tttctcctta
    29461 aggatcatcc gttatttggg tcgttttctg ctaaaatctg cgccttgcgc ttctttagcg
    29521 cactgtctat ggctaacctt ttgaataaat tcattatgac gagaatactc gctgcgataa
    29581 cccttttgct gagtatcgta ttgaccattt tggtcactat tttttgctcc gtcccgatca
    29641 tcattgccgg gattgtaaaa ctattgcttc ctgtgccagt catttggcga aaggtttcgc
    29701 gtttttgtga ttttatgatg tattgctggt gtgaaggtct ggcggtatta ctgcatctga
    29761 acccacacct gcaatgggaa gttcgcgggc tggaagggtt aagtaagaaa aactggtatc
    29821 tgcttatttg taaccaccgt agttgggcag atattgtcgt actgtgcgtg ctgtttcgta
    29881 agcacattcc gatgaataaa tatttcctca agcagcagct ggcctgggtg ccttttcttg
    29941 gcctggcatg ctgggcgctg gatatgccgt ttatgaagcg ttattcccgc gcttatttat
    30001 tacgtcatcc ggagagacgt ggtaaagatg ttgaaaccac tcggcgttct tgtgaaaagt
    30061 ttcgcctgca tcccaccacc attgttaatt tcgttgaagg ctcccgtttc acgcaagaaa
    30121 aacatcagca aacgcactcc acttttcaaa acttgttgcc accaaaggcg gcaggcattg
    30181 cgatggcgct aaatgtactg ggtaaacaat tcgataaact gcttaatgtt acgctgtgtt
    30241 atccggacaa taaccgtcag ccgttcttcg atatgttaag cggtaaactg acgcgaattg
    30301 tcgtacatgt ggatttgcag cctattgccg atgagttaca tggcgactac atcaatgaca
    30361 aaagctttaa gcgccatttt cagcaatggc tgaactcact gtggcaggaa aaagaccggc
    30421 ttctgacgtc gttgatgtca tcacagcggc aggacaagta aattttgctc gcctctgaat
    30481 gagcagaggc gagtgagtat tttaatgaac aaaacgtccg gcacgagaca taaattcttc
    30541 ttcgctcatc tcctgtccgt taaaaacaac tttacccggt gtataacgca gttgcagcga
    30601 ggcggtattg ttgtcaatcg tgattaactg caacatctga cctaaggtca tcatcccgct
    30661 gatttgttta tcagactgct tttgcgcttt ttccgcatcc attccttcag ataaattaag
    30721 ctgttttgcg gtttctgtgg cgacattaag cggtaatttc acatcaaaat tgagcgattt
    30781 aatatctttg tttgtggatg atgaagattt ggctgggtcg gcaatactga tatccagatt
    30841 ggcatttagt tcgccgagtg cattcttcca tcttaccggt tgtttaatgg tcggctcact
    30901 tttttgtaat aacggtaaat actctttgaa caatgcagta ttcacttctt gcagagcaac
    30961 ttcatcgttt gctaactcag ggtgtgcagc aagctgcttc tgcatcgcaa tgttatactg
    31021 gatgataaat tggcgcaccg ctgagggatc aatagattca gcaatcaatg accactcacc
    31081 actaccgagt tgctgattcc cttttgttaa cttatcaagt tcgtaggtca gattgacatt
    31141 gatataatct ttgtctttaa cgcgatccag cttggttttt gcaacgaaag catcgatttg
    31201 ggcaacgtct tccccgtgat tgataatgtt aatctgatta aatttcgact cgctttcacc
    31261 aaccggaaat ttcttttctt ctaatcgcgc cagagaatca atggtaaaac ttttcgccgt
    31321 tactttgttc attggtgata attgcagaac aatatcttca actttgcctt caatatccag
    31381 gttagacaat gaactatcat caccattaaa agtaaactgg ccttcaccaa aagaaaactt
    31441 tccatactct gcaggggcaa catctaatgt cgtggagaat gagccaccaa acgcgaatcg
    31501 caatgtcgct tccacgggcg atttattttt cgcggcgata aatagcggtt gtgtcagctc
    31561 attattcact aagttcactt ttgccgctgc cagtgctggg atgacattac catgcattaa
    31621 cattgtgatg ggcaacggac cgtgctcaac atccacatca aatacaactt tctggcctgg
    31681 cttgatattg agatcgggtg caccgttatc aaatgtcatt tgcatttgaa aacgggaatt
    31741 aaaaaaacct ttgtcaaaat ttttataact taacgtcatg tcgtaggcat gttcaccttt
    31801 ctatttagca tcgttaaaat ctttaataaa cttttcgaca cctggctgaa tttgcgtacc
    31861 tgtgtaccat gtgccaccac cccagattac ggataacgca acaatggcac ctgtagctga
    31921 cttacgtatc atataaatat tccctgataa aacagcaaaa ctttgaatat cca
//
LOCUS       DAFGPF010000053        30708 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFGPF010000053 DAFGPF010000000
VERSION     DAFGPF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30708
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.053"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            41..604
                     /locus_tag="LSX49_002661"
     CDS             41..604
                     /locus_tag="LSX49_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HBL7169057.1"
                     /translation="MLKKTLLSMFATALLSGVAFNALADDPNQGSGKITFKGEVIDAP
                     CSIAPGDEDQTINLGEVADTVLKSGQKSLPVDVTIHLQDCILSDGTNTVDKVKITFSS
                     ASVDATDSNLLKNTLEGNIGGATDVGVRLVKSDNTNVTLGTPITINFPTTNSYQELNF
                     KARMESLGRTATPGNVQAQANYVLDYK"
     gene            689..3211
                     /locus_tag="LSX49_002662"
     CDS             689..3211
                     /locus_tag="LSX49_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001060675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBL7169058.1"
                     /translation="MNNKNTFTGDTLSHAIKNALSGVVCSLLFVLPAHAVEFNVDMID
                     VEDRENIDISRFEKKGYIPPGRYLARVQINKNMLPQALILEWVKADNESGSLLCLTKE
                     DLTSFGLNTEFIESLQTIAGRECLDLSQRQELTTRLDKATMILSLSVPQAWLKYQATN
                     WTPPEFWDTGIAGFILDYNVYASQYAPHHGDSTQNVSSYGTLGFNLGAWRLRSDYQYN
                     QNFADGRSVNRDSEFARTYLFRPIPSWSSKFTMGQYDLSSNLYDTFHFTGASLESDES
                     MLPPDLQGYAPQITGIAQTNAKVTVAQNGRVLYQTTVAPGPFTISDLGQSFQGQLDVT
                     VEEEDGRTSTFQVGSASIPYLTRKGQVRYKTSLGKPTSVGHNDINNPFFWTAEASWGW
                     LNNVSLYGGGMFTADDYQAITTGIGFNLNQFGSLSFDVTGADASLQKQNSDNLRGYSY
                     RFNYAKHFESTGSQITFAGYRFSDKDYVSMSEYLSSRNGDESIDNEKESYVISLNQYF
                     ETLELNSYLNVTRNTYWDSASNTNYSVSVSKNFDIGDFKGISASLAVSRIRWDDDEEN
                     QYYFSFSLPLQQNRNISYSMQRTGSSNTSQMISWYDSSDRNNIWNISASATDDNIRDG
                     EPTLRGSYQHYSPWGRLNINGSVQPNQYNSVTAGWYGSLTATRHGVALHDYSYADNAR
                     MMVDTDGISGVEINSNRTVTNGLGIAVVPSLSNYTTSMLRVNNNDLPEGVDVENSVIR
                     TTLTQGAIGYAKLNATTGYQIVGVIRQENGRFPPLGVNVTDKATGKDVGLVAEDGFVY
                     LSGIQENSILHLTWGDNTCEVTPPNQSNISESAIILPCKTVK"
     gene            3227..3967
                     /locus_tag="LSX49_002663"
     CDS             3227..3967
                     /locus_tag="LSX49_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001374399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBL7169059.1"
                     /translation="MKSPLITTGMICLLGICNFAQATVSPDRTRIIFNASNKSATVRL
                     TNQSKIDPYLAQSWIEDASGKKTRGYISTLPPMERIEPDEQVQIRLMALASLNNLPQD
                     RETLFYYNVREIPPRTKEQNVMQIAMQSRLKLFWRPKAIELKEGQMVPLQKVTITRTA
                     AGLTLNNPTPYHITVGYIGTNGKTLMPGADSIMVTPFASATQYLNNLPSTFQLGFVAD
                     YGGLEMFKVECNSVQSLCQSSPAKKGKI"
     gene            3964..5013
                     /locus_tag="LSX49_002664"
     CDS             3964..5013
                     /locus_tag="LSX49_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein"
                     /protein_id="HBL7169060.1"
                     /translation="MITLFRLLAILCLFYNVSVYAVNCYQDQRGGNTQIRGTLPSFRI
                     PENAQPGQKIWESDDVNVTVYCDNATGWRADDPAENIYAWIKMPAINSADILNNPYLT
                     FGVTYNGVDYEDSDVGIDTFACLDKYEQYYGGIYHDPVCNGSTLQKNVTFNARFRAYV
                     KFKARPAVDQTWDFGVVNVLQFDGEGGANLAADNKNLRYIIDGLNNILFLDCSVDVRI
                     FPESQIVNFGQISANSIATYRPKAAFSVSTIKDVAADCTEQFDVVTSFYTTDTLHDDT
                     HLEMGNGLLMRITDQKTQEDIKFNKYKRFTTYIPGQTGAMVTRDYQAELSQKPGETLV
                     YGPFKKDLIVKINYN"
     gene            complement(5067..5720)
                     /gene="ribB"
                     /locus_tag="LSX49_002665"
     CDS             complement(5067..5720)
                     /gene="ribB"
                     /locus_tag="LSX49_002665"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HBL7169061.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITDDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     regulatory      complement(5824..5972)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            6094..6393
                     /gene="ubiK"
                     /locus_tag="LSX49_002666"
     CDS             6094..6393
                     /gene="ubiK"
                     /locus_tag="LSX49_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311957.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HBL7169062.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRISELEARNNPAAELQSPPAIPPVDKAE"
     gene            complement(6428..6628)
                     /gene="glgS"
                     /locus_tag="LSX49_002667"
     CDS             complement(6428..6628)
                     /gene="glgS"
                     /locus_tag="LSX49_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HBL7169063.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQTRELELEH"
     gene            6898..7527
                     /locus_tag="LSX49_002668"
     CDS             6898..7527
                     /locus_tag="LSX49_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HBL7169064.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEIFALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHACVTLWQSPLPNLF
                     VVPVSLLFTIIAVHYTGKVVAPWIPRDHSSAITEEEYVGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKTFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            7554..9215
                     /locus_tag="LSX49_002669"
     CDS             7554..9215
                     /locus_tag="LSX49_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBL7169065.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLSGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNAKIAAFEA
                     ERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGATGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSSLSSTTPVEEKAE"
     gene            9455..9514
                     /gene="ibsE"
                     /locus_tag="LSX49_002670"
     CDS             9455..9514
                     /gene="ibsE"
                     /locus_tag="LSX49_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsE"
                     /protein_id="HBL7169066.1"
                     /translation="MMKFVIILVVLLLLSFPTY"
     gene            complement(9634..11067)
                     /gene="hldE"
                     /locus_tag="LSX49_002671"
     CDS             complement(9634..11067)
                     /gene="hldE"
                     /locus_tag="LSX49_002671"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HBL7169067.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQLDKKG"
     gene            complement(11115..13955)
                     /gene="glnE"
                     /locus_tag="LSX49_002672"
     CDS             complement(11115..13955)
                     /gene="glnE"
                     /locus_tag="LSX49_002672"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HBL7169068.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQD
                     SVIAHPEWLTELESQPPQADEWQHYAAWLQEALSNVSDEAGLMRELRLFRRRIMVRIA
                     WAQTLALVTEESILQQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSDGVYANELR
                     ALLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSAIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQT
                     QTLPSDELNRARLAWAMDFADWPQLTGVLTAHMANVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLMLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHL
                     ALQELPGHVSEDCFTAERELVRASWQKWLVEE"
     gene            complement(13978..15279)
                     /gene="ygiF"
                     /locus_tag="LSX49_002673"
     CDS             complement(13978..15279)
                     /gene="ygiF"
                     /locus_tag="LSX49_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HBL7169069.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPTDLASRVQPLFSTDFYREKWLVEVDGSRIEIALDQGEVKAGEFAEPICELE
                     LELLSGDMRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHTLMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQSKM
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQ
                     DWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            15521..16141
                     /locus_tag="LSX49_002674"
     CDS             15521..16141
                     /locus_tag="LSX49_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBL7169070.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINRLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPSRKRKDRWMN"
     gene            16205..17443
                     /gene="cca"
                     /locus_tag="LSX49_002675"
     CDS             16205..17443
                     /gene="cca"
                     /locus_tag="LSX49_002675"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HBL7169071.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVSLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALM
                     REMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDSLFGVPA
                     PARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAVASWKEQRCPKPD"
     gene            complement(17523..18344)
                     /gene="bacA"
                     /locus_tag="LSX49_002676"
     CDS             complement(17523..18344)
                     /gene="bacA"
                     /locus_tag="LSX49_002676"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL7169072.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGENKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(18435..18803)
                     /gene="folB"
                     /locus_tag="LSX49_002677"
     CDS             complement(18435..18803)
                     /gene="folB"
                     /locus_tag="LSX49_002677"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HBL7169073.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            18908..19525
                     /gene="plsY"
                     /locus_tag="LSX49_002678"
     CDS             18908..19525
                     /gene="plsY"
                     /locus_tag="LSX49_002678"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBL7169074.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            complement(19538..20470)
                     /gene="ttdR"
                     /locus_tag="LSX49_002679"
                     /gene_synonym="dan"
     CDS             complement(19538..20470)
                     /gene="ttdR"
                     /locus_tag="LSX49_002679"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
                     /protein_id="HBL7169075.1"
                     /translation="MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQIL
                     ENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGC
                     SFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDAIPDYYIAH
                     LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVK
                     VSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVRVLPEYAQSANIWAVYR
                     EPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM"
     gene            20677..21588
                     /gene="ttdA"
                     /locus_tag="LSX49_002680"
     CDS             20677..21588
                     /gene="ttdA"
                     /locus_tag="LSX49_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HBL7169076.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            21585..22190
                     /gene="ttdB"
                     /locus_tag="LSX49_002681"
     CDS             21585..22190
                     /gene="ttdB"
                     /locus_tag="LSX49_002681"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HBL7169077.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            22238..23701
                     /gene="ttdT"
                     /locus_tag="LSX49_002682"
     CDS             22238..23701
                     /gene="ttdT"
                     /locus_tag="LSX49_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate/succinate antiporter"
                     /protein_id="HBL7169078.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALLPLPAGLESHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHAMLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTIVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTADYWRLGAIFGLIFLVLLVITGLLWMPVVLL"
     gene            complement(23744..24757)
                     /gene="tsaD"
                     /locus_tag="LSX49_002683"
     CDS             complement(23744..24757)
                     /gene="tsaD"
                     /locus_tag="LSX49_002683"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBL7169079.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQEALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     DVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            24995..25210
                     /gene="rpsU"
                     /locus_tag="LSX49_002684"
     CDS             24995..25210
                     /gene="rpsU"
                     /locus_tag="LSX49_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBL7169080.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            25321..27066
                     /gene="dnaG"
                     /locus_tag="LSX49_002685"
     CDS             25321..27066
                     /gene="dnaG"
                     /locus_tag="LSX49_002685"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL7169081.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVAMSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            27261..29102
                     /gene="rpoD"
                     /locus_tag="LSX49_002686"
     CDS             27261..29102
                     /gene="rpoD"
                     /locus_tag="LSX49_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBL7169082.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDTADDDNSIDPELAR
                     EKFAELRAQYIVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(29180..29686)
                     /gene="mug"
                     /locus_tag="LSX49_002687"
     CDS             complement(29180..29686)
                     /gene="mug"
                     /locus_tag="LSX49_002687"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HBL7169083.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            29811..29886
                     /locus_tag="LSX49_002688"
     tRNA            29811..29886
                     /locus_tag="LSX49_002688"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29844..29846,aa:Ile,seq:cat)
     gene            complement(29940..30704)
                     /gene="nfeF"
                     /locus_tag="LSX49_002689"
     CDS             complement(29940..30704)
                     /gene="nfeF"
                     /locus_tag="LSX49_002689"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase"
                     /protein_id="HBL7169084.1"
                     /translation="MNNTPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEGSRPPSRDYTPLYDELRHELAID
                     FFIHDGGVASGWAMQAKPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFETEQYDPQRVRAAAYWHAK"
BASE COUNT         7718 a         8152 c         7554 g         7284 t
ORIGIN      
        1 cccattcaca gcctatccta atctataaag gattatagtc atgttaaaaa aaacattgtt
       61 atctatgttc gcaaccgcat tgttatctgg cgttgctttt aacgcgcttg ctgatgaccc
      121 aaatcagggt tctggtaaaa taacatttaa aggtgaagtt atcgatgcgc cttgttctat
      181 tgctcctggt gatgaagatc agacaataaa cctcggtgaa gttgctgata ctgtattaaa
      241 aagcggacag aaatctcttc ctgtagatgt caccattcac ttgcaggatt gtattttatc
      301 tgacggcact aacactgttg ataaagtcaa aatcaccttt agttctgcca gtgttgacgc
      361 taccgactcc aacctgctta aaaacactct ggaaggtaac atcggcggcg caactgatgt
      421 aggcgtacgt ctggtgaaat cagacaacac caacgtgact cttggcactc caatcactat
      481 caacttcccg acgactaact cctaccagga gttgaacttt aaagcccgta tggaatctct
      541 gggacgcacc gcgaccccgg gtaacgtgca ggcacaggcc aattacgtac tcgactacaa
      601 gtaagcggca attaatacgc acaacgtcag acggtaaagc cgatgatatg tcatcggcaa
      661 ctttgggtct tttttgaaat ggatttttat gaacaataaa aacacgttta ccggggatac
      721 attatcccac gcaattaaaa atgccctgtc tggcgtagtg tgttcgctac tcttcgtttt
      781 acctgcccat gcagtggaat tcaacgttga tatgattgat gttgaagacc gtgagaatat
      841 cgacatctct cgttttgaga aaaaaggcta tatcccccca ggcagatacc tcgctcgtgt
      901 gcaaataaat aaaaatatgt tgccacaagc gttaatactg gaatgggtaa aagccgataa
      961 tgaaagtggt tcgttactct gcttaaccaa agaagatctg actagtttcg gtcttaatac
     1021 ggaatttatt gaatcattgc aaaccatagc tggcagagaa tgtctcgatt taagccaacg
     1081 tcaggagtta acgacacggc ttgataaagc tacgatgata ttatcgctaa gtgttcccca
     1141 ggcgtggtta aaataccagg caacaaactg gacgccacca gagttttggg ataccggtat
     1201 cgccgggttt atccttgatt acaatgtgta cgccagccaa tatgccccac atcatggaga
     1261 cagcacccaa aacgtcagct cctatggtac gttaggcttt aacctcggcg catggcgctt
     1321 acgtagcgat taccaatata atcagaattt tgctgatgga cgctcggtaa accgcgacag
     1381 cgaatttgcg cgaacttatc tgtttcgccc tatcccctcc tggtcgtcaa aattcactat
     1441 gggccagtac gacctgagct ccaatcttta cgataccttc cactttactg gcgcatcgct
     1501 ggaaagtgat gaaagcatgc tgccgccaga tttacagggt tatgcgccac aaattaccgg
     1561 catcgcgcag accaacgcga aagtaactgt ggcacaaaat ggtcgtgtac tttatcaaac
     1621 cactgtcgcg ccaggccctt ttactatttc tgatttgggg caatcgtttc aggggcagct
     1681 ggatgtcaca gtggaagaag aagatggccg caccagcacc ttccaggttg gatccgcatc
     1741 cattccctat ttaacccgta aagggcaagt gcgctataaa acgtcgctgg gaaaaccgac
     1801 atccgtcggg cataacgata tcaataatcc ctttttctgg acggcggaag cctcctgggg
     1861 ctggttgaac aatgtgtcgc tgtatggtgg cggcatgttc accgctgatg attatcaggc
     1921 tatcactacc ggtattggct ttaatcttaa ccaattcggt tcgctttctt ttgatgtcac
     1981 cggagcagac gcgtctttgc agaaacaaaa tagcgacaat ctgcgtggtt acagctatcg
     2041 cttcaactat gcaaagcatt tcgaatcgac aggtagtcag attaccttcg cgggttatcg
     2101 cttctcagat aaagattacg tgtcgatgag tgagtaccta agctcgcgta atggcgatga
     2161 gtcaattgat aatgaaaaag agagttatgt catttccttg aaccagtact ttgaaacact
     2221 ggaattaaac tcttatctca acgttacacg caatacttat tgggacagcg ccagcaatac
     2281 caactactcc gtatctgtaa gcaaaaactt tgatattggc gatttcaaag gtatctctgc
     2341 atcgctggca gtaagtcgaa tccgctggga tgacgacgaa gagaatcaat attacttctc
     2401 tttctctcta cctttacaac aaaaccgcaa catctcctac agtatgcagc gtacgggaag
     2461 cagtaatact tcgcagatga tttcctggta cgattcatca gatcgcaaca atatctggaa
     2521 tatttcagcg tcggcaacgg acgacaatat acgtgatggc gaaccaacac tgcgcggcag
     2581 ctaccagcac tattcaccgt ggggacgtct gaacattaac ggcagtgtac agccgaatca
     2641 gtacaattct gttaccgcag gctggtacgg ttcacttacc gctacacgtc atggtgtcgc
     2701 ccttcacgat tatagctatg ctgataacgc ccgcatgatg gtcgataccg acggcatctc
     2761 cggcgttgaa atcaactcta accgaactgt taccaacggg ctgggcattg ccgttgtacc
     2821 ttcgttatcg aactacacca cctccatgtt gcgggtgaac aataacgatc tgccagaagg
     2881 tgtcgatgtc gaaaactcgg ttattcgtac tacgctcacc cagggtgcca tcggctacgc
     2941 aaaactgaat gccaccaccg gataccaaat cgtcggcgtt attcgtcagg aaaatggccg
     3001 cttccctcca ctaggtgtga atgtcacgga taaagcgaca ggtaaagatg tgggcctggt
     3061 cgcggaagac ggcttcgttt atctcagcgg tattcaggaa aacagtattc tgcatttaac
     3121 ctggggtgat aatacctgtg aagtcacgcc gccaaaccaa agtaacatta gcgaaagcgc
     3181 aataatttta ccttgtaaaa cagtcaaata attcaggatg aatataatga aatcaccatt
     3241 aatcacaaca ggaatgattt gtttactggg gatctgcaat tttgcccagg cgactgtctc
     3301 ccccgacagg acacgtatca tttttaatgc ttcgaataaa agcgcaacgg tccgtctgac
     3361 taaccaaagt aaaatcgatc cctatctggc tcagtcgtgg attgaagatg ccagcggtaa
     3421 aaaaacgcgt ggttacatat caacactgcc gccgatggaa cgtattgagc cggatgaaca
     3481 ggtacaaatt cgcctgatgg cgctggcctc attaaacaac ttaccgcagg acagagaaac
     3541 gctgttctac tataacgtgc gggaaattcc gcctcgcact aaagaacaga atgtgatgca
     3601 aatcgccatg cagagtcgac tgaaattatt ctggcgtccg aaagcaatcg aattaaaaga
     3661 agggcagatg gtgcctttac aaaaagtcac aataacacgg accgctgcag ggctgacact
     3721 caataatcca acgccttatc acatcaccgt cgggtatatc ggtactaacg gcaagacact
     3781 gatgcccggt gcagacagca ttatggtgac tccgtttgct tctgcaactc aatacttgaa
     3841 caacttgccc tcaactttcc agttaggctt tgttgctgac tatggtggac tggagatgtt
     3901 taaagtcgaa tgtaattccg tccaatccct ctgccaaagc tctcctgcta agaagggaaa
     3961 aatatgatta cgcttttccg tttactggcg attctttgcc ttttttataa cgtttcagtt
     4021 tatgctgtaa attgctatca ggatcaaaga ggtggtaata cacaaatacg tggtacttta
     4081 ccttccttca gaattccaga aaacgcccag ccgggacaaa aaatttggga aagcgatgac
     4141 gttaatgtta cggtatattg tgataacgcg acaggatgga gagctgatga tcccgcagaa
     4201 aatatttatg cctggattaa aatgccggct ataaatagtg cagacatttt gaataaccca
     4261 tacctgacat tcggtgtaac ctataatggt gtggactatg aagatagcga tgtaggaatt
     4321 gatactttcg cctgtctgga taagtatgaa cagtattatg gtggtattta tcatgatcca
     4381 gtttgtaatg gcagcaccct acaaaaaaat gtcacgttta atgcccgttt tcgcgcatat
     4441 gtgaaattta aagcacgtcc agcagtggat caaacctggg attttggcgt ggtaaatgtt
     4501 ctgcaatttg atggtgaagg tggtgctaac ttagcagcag ataataaaaa tctacgttat
     4561 attattgatg gattaaataa tattttattt cttgattgta gtgtcgatgt ccgtattttt
     4621 ccagaaagcc agatcgttaa tttcgggcaa atctctgcaa actctattgc tacttatcga
     4681 cccaaagctg catttagcgt atctactata aaagatgttg ctgccgactg taccgagcaa
     4741 tttgatgttg tcaccagttt ttatacgaca gatacgttac atgatgatac gcatctggaa
     4801 atgggtaatg gtttgttaat gcgtattact gatcaaaaaa cacaagaaga cattaagttt
     4861 aataagtaca aacgcttcac cacatatatt ccaggtcaga ctggagcgat ggttacccgt
     4921 gattaccagg ctgaactttc acaaaaaccg ggggagactc tcgtttatgg gcctttcaaa
     4981 aaagatctca tcgtaaaaat aaactataac tgaacagcaa aatgccggga acaccccggc
     5041 attttcatat ttagtatttc acgtcattag ctggctttac gctcatgtgc ctgacggtat
     5101 gccaccaggt cttcaatagt cacgagcgcc atattgtgtt tattcgcaaa ctcaatgcac
     5161 tctggtgcac gcgccatcgt gccatcgtca ttagtcagct cacacagcac accagctggt
     5221 ttaaagcctg ccagcgtcat cagatcgata gtcgcttcag tatgaccgcc acgcgtcagt
     5281 acaccacctg cctgcgcgcg aagtgggaaa acgtggcctg ggcgattcag atctgaaggt
     5341 tttgcgccat cggcaatcgc tgcgcgaacg gtcgtaatac ggtcagcggc agaaacaccg
     5401 gtagtcacac cttcagctgc ttcaatggtc acggtaaaac cggtgccata ggcgctggtg
     5461 ttattttcta ccatcattgg cagatcgagt tgtttacggc gatcgtcagt aatgcacagg
     5521 caaacaatac cactcccgtg gcgaatggtc agcgccatct gctcaacggt catggtttct
     5581 gccgggaaga tcatatcgcc ttcgttttca cggtcttcat catcaagcac catcacaccg
     5641 cgtccttcac gcagcgcagc cagtgcattt tcaacacgtt cgaaaggcgt accaaaagag
     5701 gaaagtagcg tctgattcat ggtaaaaaaa cctcactaaa attatggtta ccagaatcag
     5761 ggcagtctta ggagtggcgg catatagcca aaataacgtg agcgggtcca tgcccgacag
     5821 aatcgttact ctctcccatc cggactctaa ccgtcggccc cggaattaca ccggatctgc
     5881 tgtcctttga gttcgcaccc aaagcgctcg cgggctttca actgagttga tttaccgccg
     5941 gtggggaatt tcgccccgcc ctgagaataa gcggattcac tataacgcta atgattagcg
     6001 ccagcaacgc atagcttcac ataattctgg tttatgactt acccttatcg cactacaatg
     6061 gcactcaaca cctatcagta cagggaaact acaatgattg acccgaaaaa aattgagcaa
     6121 atcgctcgcc aggttcacga atcaatgcct aaaggaatca gggagttcgg ggaagatgtg
     6181 gagaaaaaaa tccgccaaac cctacaagcg cagctgacgc gtctcgatct ggtaagccgc
     6241 gaagaattcg acgttcagac gcaagtcctg ttacggactc gtgaaaaact ggcgttactg
     6301 gagcagcgca tcagcgaact ggaagcgcgc aataatccgg cagcagaact tcaatctcct
     6361 ccggctatcc cgccagttga taaagcagaa taaagcacca caaaaacggg ccagacggcc
     6421 cgtaatatca gtgttctaat tcaagttctc tggtttgcat catctgttgg caataccagg
     6481 cataacgtgc gcaaaaccag gttctatgtt cttcatccat gttaccagta acggccagaa
     6541 tatcgaccgg gcgaccttct gcgtgcattc tggcaaaact acgcgcgaga aaatcgaaat
     6601 tatttaaaga attaagacta tgatccataa gcacatcctc cggttattgc atacctttta
     6661 aggccatatg ctttttctga tttcagtatt ccccaattag tgtagtgcct ttaaacataa
     6721 cgtgcgtaaa tatattgtcc ccgatcacac tttttagtga aaaataaaaa aaccatatta
     6781 aaagactttc tcttccagaa cttctcaaac atgtgttatt attaacaaag ataaaagtaa
     6841 tcaaggaaac tattccaaag taaatattgc gtcactaaat ggacattgga gtgacatatg
     6901 attttattcg ccgactataa caccccttat cttttcgcta tttcctttgt actcttgatc
     6961 ggccttttag aaatttttgc acttatctgc ggtcacatgc tctccggtgc tcttgatgca
     7021 catcttgacc attatgattc cataaccaca ggtcatatta gccaggcact tcattatctc
     7081 aatattggaa gattgccagc tctcgtcgtc ctctgcttac tcgctggttt ttttggtctt
     7141 attggcatcc tgttgcaaca tgcctgcgtt acgctctggc aatcaccact ccccaacctg
     7201 ttcgtggttc ctgtcagttt actgtttaca attattgcag tgcattatac cggtaaagtc
     7261 gttgcaccct ggattccacg cgaccatagt tcagctatta cagaagaaga atatgttggt
     7321 agcatggcat taattaccgg ccatcaagcc acttcaggta acccctgcga aggaaaactc
     7381 accgatcaat ttggccaaat acattatttg ctactggagc ctgaagaagg aaaaactttc
     7441 actaaaggag acaaagtgtt aattatttgc cgactttctg caacgcgata tttggcggaa
     7501 aataatccct ggccccagat attgtgattt attaatcaaa aggaaattta ataatggatg
     7561 atatcgttaa ttctgtgccc tcctggatgt ttaccgcgat tatcgccgta tgcattctgt
     7621 ttattattgg aattattttc gccaggctct atcgtcgcgc ttcggcagag caagcatttg
     7681 ttcgtactgg tttaagtggg caaaaagtgg tgatgagcgg tggcgcaatc gtgatgccga
     7741 tctttcatga aataattccc atcaatatga ataccctgaa gctggaagtc agccgctcaa
     7801 ccattgatag cctgattacg aaagatcgta tgcgcgtcga tgtcgtggtt gctttctttg
     7861 tgcgggtaaa accttcagta gaagggattg ccaccgccgc ccagacgctg gggcaacgca
     7921 ccctgtcgcc tgaagactta cgtatgctgg tggaagataa atttgtcgat gccctccgtg
     7981 caacagcggc acaaatgacc atgcatgagt tacaggatac ccgcgagaac ttcgtgcagg
     8041 gagtacaaaa taccgtagct gaagatctgt cgaaaaatgg cctggaactg gaaagcgttt
     8101 cacttaccaa ctttaaccag acctcgaaag aacatttcaa tccgaacaat gcctttgacg
     8161 ccgaaggttt aaccaaactg actcaggaga cggagcgccg tcgtcgcgaa cgtaacgaag
     8221 ttgaacagga tgtggaagtc gcagtgcgtg agaaaaaccg tgatgcactt tcgcgcaagt
     8281 tggagattga acaacaagaa gcgtttatga cgcttgagca ggagcagcag gttaaaaccc
     8341 gtaccgctga gcagaatgcg aaaattgcgg cttttgaagc tgaacgtcgt cgtgaagcag
     8401 agcagacgcg aattctggct gaacgacaga ttcaggaaac ggaaatcgac cgcgaacagg
     8461 ccgtccgctc aagaaaggtt gaggccgaac gtgaagttcg cattaaagag atcgaacagc
     8521 agcaggtcac cgaaatcgct aaccagacga aatcgatcgc tattgccgcc aaatcggaac
     8581 aacagtccca ggcagaagcg cgtgctaacc ttgcactcgc agaagcagta agcgcccaac
     8641 aaaacgtaga aaccactcgc cagactgccg aagccgatcg tgctaaacaa gtggcgttga
     8701 tcgccgcagc gcaggatgca gaaaccaaag cggttgaact gaccgtgcgg gcgaaagcag
     8761 aaaaagaagc cgcagaaatg caggcggcgg ctatcgttga gttagccgaa gctacacgta
     8821 aaaagggtct ggcggaagca gaagcacaac gtgcgctgaa cgatgctatc aacgtacttt
     8881 ctgatgaaca aaccagcctt aaattcaaac tggcattatt gcaggcgctg cctgcggtaa
     8941 ttgagaaatc cgttgagcct atgaagtcta tcgacggcat caaaattatt caggtcgatg
     9001 gtctgaatcg tggcggcgct acgggtgatg caaacacggg taatgtgggg ggcggaaacc
     9061 tggcagaaca agcgttatca gccgcactct cttaccgcac acaggcaccg ctgattgact
     9121 ccttgctcaa tgaaattggc gtttcaggcg gctcactggc ggcattgact tcatccttaa
     9181 gctcaacaac tcccgtcgaa gaaaaagcag agtaaaccct cttctatgaa taatccctgg
     9241 cccaaaaagc cggggatttt ttatatctgc gttccgctaa aaggtgcaaa tgatcaggct
     9301 gttgcagcat tttgcgtgac tgctcgggga aggcaaaact gcctctggga aagcgttgcg
     9361 cggggtccgg cgctcatcaa caatcgggga gtcagcaagg ggctgaaacg ggaaagcccc
     9421 tcccgaggaa ggggccttat agaaggaaag ggttatgatg aagttcgtca tcatactggt
     9481 tgtgttgtta ctgttaagtt tcccgactta ctaacaactc atcagagggg ggagaaatcc
     9541 tcccttaccc ttgttccttt actttaggtt gaaaaaacaa cagcgtcaat agacctgcct
     9601 gctacgaagc gagatctgtg aaccgctttc cagttagcct tttttatcca gttggatctt
     9661 cttgatgatg ttggtcgtcg agcaaccgtc ttcaaagttg agcaccagca cttcgccacc
     9721 gttggcccag acttctttac tcccggcaat ctcttctggt ttatagtcgc cgcctttcac
     9781 cagcagatct ggcaagatcc cggcgatcaa gcgctgcggt gtgtcctctt caaacgacac
     9841 cacccagtcg accgcttcca gtgcgcccag cacaatcata cgctgttcga gcgggttaac
     9901 ggggcgggaa tcccctttca gccgtttggt ggaggcatcg ctgttcacag cgacaatcaa
     9961 acggtcaccc agtttacggg catttgccag ataagagacg tgcccggcgt gcaggatgtc
    10021 aaagacaccg ttggtcatca ccactttttc accgcgttta cgcgctgccg ctacagcaag
    10081 cttcagttcc tcttcggtca tcacaccaaa gccggtatct gcacgtccac gtactgcgtt
    10141 ttccagctcg atcggcgaaa ccgtggatgt ccccagtttg ccgaccacca caccagccgc
    10201 cgcattggca aagaagcagg cttcttccag cgaattaccc gctgccagcg ttgccgccag
    10261 gacgccaatc accgtgtcgc ccgcaccggt aacgtcatac acttcctgcg cctgggttgg
    10321 catatgcagc ggcgctttac ccggttgcag cagcgacata ccctgttcgg aacgggtcac
    10381 taacagagcc gagagttcgt aatcggcaat cagtttcatg ccgcgctcaa caatctcttc
    10441 ttcggtctta catttaccga caacagcttc aaattccgag agattcggcg ttaacagcgt
    10501 agcgccgcgg tagcgctcaa aatcggtacc ttttggatca atcagcaccg gaacacccgc
    10561 tttacgcgcc agttggatca tctgctgtac gcttgccagc gcacctttgg cgtagtcaga
    10621 aagcaccagc gcgccaatcg aactcagtgc ctgattaatc cgctcgtgca gcggctgcgg
    10681 atcaacccct tcgaaacctt cttcgaaatc cagacggatc agctgttggt tacgggaaag
    10741 tacccgtaat ttggtgatag tcggatgcgt cggtacagaa acaaagtcgc atttaacgtt
    10801 gacgtcggcc agagatttac tgagcgcgcg cgccgcatcg tcaatgcccg tcaacccgac
    10861 caggcgtgca ttagcaccga gagaagcgat attcatcgcc acgttagccg cgccgcccgg
    10921 acgttcttcg atggtattca ctttaaccac gggtaccggc gcttccggcg agatacggct
    10981 ggtgggaccg taccagtaac gatccagcat cacatcacca accaccatca ctcctgcacg
    11041 ttcaaactct ggcagcgtta ctttcattcc tgtctcctga gagattcaaa atttgcgcgc
    11101 gataatacca tacttcattc ttccaccagc cacttctgcc agcttgcccg caccagttca
    11161 cgctctgcgg tgaagcaatc ctccgacaca tggcccggca attcctgtaa tgccagatga
    11221 tgaagttcat cgcgcagcgt cgtgtaagca cgggtcagcg ccatcgcttc ctgctcttcc
    11281 ataatgtcgt tttgcgccag tagttccaga atgcgcacgt tgtctgacca gcgcgttaac
    11341 ttcggttttt cgtgagcgta gcgcaacacc agatattgag taataaattc gatatcggta
    11401 attccgcctt catcggcttt gatatcaaag cgatcgcgat gtttattgcc gagatgggca
    11461 cgcattttct cgcgcatttc ccgcacttct gtttgcaggg ttttgccttc gcgcggcagc
    11521 gtcataatct cccggcgtac tgcgtcaaag tgcgcggtga gctgcggatc gccgtacact
    11581 acacgcgcac gcaccagcgc ctgatgctcc cacgtccagg cctcgttttt ctgataatca
    11641 gcaaatgctt ctgcggatgt caccagcatt cccgccgccc cggacggacg cagtcgtgca
    11701 tccacttcat acaaaatgcc ggaagaggtt cgcgtactga acagatgcat aatgcgttgc
    11761 gccagacgca gataaaactg tcgcccgtcg atttcccgct cgccgtcagt catcgcatcc
    11821 attgggcaat catggaggaa gatcaggtca agatcggaac tgtagcctaa ctcccagcca
    11881 cccagcttgc cgtagccgac caccgcaaaa ccacgccctt cgcgttcgtt caggtgattt
    11941 ggcttaccgt agcgggcaac catttgaacc cacgcctgct gaacgacggc atcaatcatg
    12001 gcttctgcca gccaggttaa gtgatcgctc actttcatta ccggtagcgt accggcgata
    12061 tccgctgccg caatgcgtaa cagctgcgcc tgtttgaact gacgcagcgc ctcaagctgt
    12121 tgttcttcgt catcttccgg cacgcgcagc aaatactggc gcagttcatc acggtaggca
    12181 tccgtcgccg ttggttggta gagggtattt ggatcgagca attcatccag caataatgga
    12241 taacgcgcta gctggctggc aatcatcggc gatgcagcac acagagaaat caaatgctta
    12301 agcgccgcag ggaattcact aagcagctca agataagtgg tgcgagtaac aatccccacc
    12361 agcaaggcgg taatgcgcga cagcgtgaca gcagcgtctt cacgcgcaca gacatcactt
    12421 agcagatgtg gcatcagatg gtcgagcacc tgacgtcctc gcggcccgat ggtgcgctta
    12481 tccagctctt tgcggaaatc agcaatcagc attagcacct gtttgcgatc atcctcgcta
    12541 agatgcgcca gcactggcgt ggtgtcatct tcctgcaacg catcctgcca cagctcacgc
    12601 cactgttccg acagcgactc ttcctgagtt tcactttcgt cgtcgccaat caattcatta
    12661 aacacccggc gcacattggc catatgtgcg gtcagcaccc cggtcaattg cggccagtca
    12721 gcaaagtcca tcgcccacgc cagccgcgca cggttaagct catcagaagg aagcgtctgg
    12781 gtttgttcgt cgttaatgct ttgcagcagg ttttccagac gccgcaggaa cagatacgcc
    12841 actcgcaatt gttcagcatc gttttcagaa agcagatgca gcgcggcaat ggcgctgagc
    12901 gttggcagta aagagcgcga ttgcagcgac ggttcgcgcc cgccgcgaat gagctggaac
    12961 acctggacga taaattcaat ttcgcgaatg ccgcctgcgc caagtttgat gttgtcggtc
    13021 aaaccgcgtc gacgcacttc acgggcaatc attcctttca tgttgcgcag cgactgaatc
    13081 acgctgaaat cgatgtaacg acggaaaaca aacgggcgca gcaacgcacg caactcgtta
    13141 gcatagacgc cgtcgctatc ccccataatc cgcgccttga ccatcgcgta acgctcccag
    13201 tcgcgcccct gctcctggta ataatcttcc agcgccgcaa agctcagcac cagcgggcca
    13261 ctttccccaa acggacgcag ccgcatatcc acgcgataga cgaagccatc ctgcgttggt
    13321 tgatccagta ctttaatcag ccgctgcccc atgcgggtaa aaaactgcgc gttatccagt
    13381 tcccggcgtc cgccctgggt acaaccatgt tccggccagg caaaaatcag atcgatatct
    13441 gaggagaaat tcaattcccc gccgcccagc ttacccatgc ctaaaatcag cagcggttgc
    13501 gcttcgccct gcgcattgca cggcgttccc cattcgcggc agcaggcgtc atacagccag
    13561 tcacgcgccg caacaatcag cgtctccgcc agatggctga gctgctgcaa tatgctctct
    13621 tcagtaacca gtgccagcgt ttgcgcccag gcgatgcgca ccataatgcg ccgccggaat
    13681 agccgcagct cgcgcattaa cccagcctcg tcactcacat tactgagcgc ctcctgcaac
    13741 catgcagcgt aatgctgcca ttcgtcggcc tgcggcggtt ggctttccag ttccgtcagc
    13801 cactctggat gcgcaatcac gctgtcctgc acaaaatcac tgaaagtaag tactgacttc
    13861 gcctgtgcgc taagtgattc ctcggctaaa ggctctggca gccgctcaac aacggtctgc
    13921 cagtactgct gtaacggtga agagagcggc ttcataagcg attttatcct tgcctgatta
    13981 acgttttccg ctgtgcaacc agaacggttc ctgattgttt gcctcattac ggaaatgttc
    14041 aatttcaatg cgttgcccgg tcgcaatagc gtgacgcagc ccctgccagt tctccagcca
    14101 gtcttgcgcg acgacaggat cgtagtaacc cgccagcaac agtattgagt caatatcacg
    14161 cgtcaggcgt ggcaattggt cacggtagcg atcgcctaac ggctggcaga aaacgctttt
    14221 cagttcagcg gcatggcggg aaagatggat atcggcaaag cgtttgaagg aatcgctcat
    14281 tttactctgc gctttggcat ctaaaaacgg ctgccaggct ttgcttacca gccattcggt
    14341 caacgccagc ttcgccattg ccgtttcggt agagtagacc gccgttacgg cagaaaccgc
    14401 agaagcaatg gtcgcctcgc attgagtcag cagatcacgt aagtgagtgc tcgctttacg
    14461 cggcacaatg ccaccgaaca gcatcagtgt atgacgaacc aggccaatgg ctgccagcac
    14521 ctgctctttc gccgcatcgt tgccgcgtac ccacagttct tcatgatact gccattgcgc
    14581 taacgccagc tcgagcgccg cttccagccc ctgttccaca tcagcttttg ccgcaacatg
    14641 caaaatggtg gtcggtttga tttcacgcgc cggattgccc tgcgccagat gatagccacg
    14701 cgctgctttg ctcaggctgc cctggcgtaa tccggtttgc gataccagtt ggttcgccag
    14761 tttcagcacc gcacgcatgt cgccgctaag cagttccagt tccagctcac agataggttc
    14821 agcaaattca cccgctttca cctcaccctg atcgagagcg atttcaattc ggctgccatc
    14881 gacctctact agccattttt cgcgataaaa atcggtgcta aacagcggct gcacgcggga
    14941 agcgagatcg gtaggcaatt cgccgttcgg ccagacttcc gtcggtaact gcgccaggtc
    15001 gagcgtcggt tcgctcaacg ccacgttata ttccgggcgc tggtgtaagc cgcctgtcac
    15061 tcttcctgca actttcatgg tcatctcata gcgaccgttt tcgccacgaa tacgcaagcc
    15121 catgtcgtgc ccacgcagcc aattatccgg cgtttcgtag taaatattca gcaactgcac
    15181 ggggtcatgg tgctcgccgc ccagcgtatt gagatggtca cgcagcgcct caacggcact
    15241 gtgattaaca ataaacttta attcgatttc ctgagccatg gcctttactt actggttatg
    15301 tcacataagt gacgatgaac ggcgaactta atgcgatctt ttttgtcagt agatagtatt
    15361 ttgcgccaaa ttgccatgca acgggcaatt tgacgggcgt aaaagtttga agcagtggca
    15421 agacctgaca cagaggattc cgattgatgt cgaatgcttt gcgtagcgac actgatgcca
    15481 ctactatcgt tccactttcc atgacaataa cgacagcctg atgccaaaat tacgcctgat
    15541 cggattaact ttactcgcac ttagcgcgac tgccgtctca cacgctgaag aaacgcgcta
    15601 tgtttccgac gaactgaata cctgggtccg tagcggtccg ggagatcatt atcgcctcgt
    15661 gggcacggtt aacgccggcg aggaagtgac cttattacaa actgacgcca acaccaatta
    15721 tgcccaggtg aaagacagct ctggccgtac tgcctggatc ccgttgaaac aacttagcac
    15781 tgaaccaagc ctgcgctccc gtgtgccaga tctggaaaat caggtcaaaa ctctgaccga
    15841 taaactcacc aatatcgata acacctggaa tcagcgcacc gcagaaatgc agcaaaaagt
    15901 ggcgcagagt gacagcgtga tcaacaggtt aaaagaagaa aatcagaaac tgaaaaacga
    15961 gctgattgtc gcgcagaaaa aggtcgatgc cgccagcgta cagttggatg acaaacagcg
    16021 caccatcatc atgcagtggt ttatgtatgg cggtggcgtg ctggggcttg gcttgctgct
    16081 tggtctggta ctgccgcacc tgatcccaag ccgcaaacgc aaagatcgct ggatgaacta
    16141 aatcgccttc ttcgttgcac tgtcttatta ttaggaattg tgtatttgac gaagggatga
    16201 tggcgtgaag atttatctgg tcggtggtgc tgttcgggat gcattgttag ggctaccggt
    16261 caaagacaga gattgggtgg tggtcggcag tacgccacag gagatgctcg acgcgggcta
    16321 ccagcaggta ggccgcgatt ttcctgtgtt tctgcatccg caaacgcatg aagagtatgc
    16381 actggcacgt accgaacgga aatctggttc cggttacacc ggttttacct gctatgccgc
    16441 accggatgtc tcgctggaag atgatcttaa gcgtcgcgat ctgaccatta atgcgctggc
    16501 ccaggacgat aacggcgaga ttatcgaccc gtacaacggt ctgggcgatc tgcaaaatcg
    16561 tctgttgcgc catgtttccc ccgcttttgg cgaagatccg ttacgcgtgt tgcgcgtagc
    16621 gcgttttgct gcgcgttatg cccacctcag tttccgtatt gccgatgaaa ctctggcgct
    16681 gatgcgcgag atgacccatg cgggtgaact ggaacacctg acgcctgaac gggtatggaa
    16741 agagacggaa agcgccctca ccacccgcaa tccccaggtg ttcttccagg tactgcgcga
    16801 ttgcggcgca ctgcgcgttt tattcccgga aattgactcc ctgtttggcg ttccggcccc
    16861 tgccaggtgg cacccggaaa tcgacacggg tattcatacc ttaatgacgc tctcaatggc
    16921 ggcgatgctg agtccgcagg tcgatgttcg tttcgcaacg ttatgccacg atctcggtaa
    16981 aggactgacg ccgccagaac tttggccacg tcatcatggt catggcccgg cgggtgtgaa
    17041 gttagtggaa caactatgcc agcgtctgcg cgtgccaaat gaaattcgcg atttagccag
    17101 actggtagct gagtttcacg atctcatcca cacctttcca atgctgaacc cgaaaaccat
    17161 tgttaaattg tttgattcca ttgacgcctg gcgtaaaccg cagcgtgtcg agcaactggc
    17221 gctgaccagc gaggctgacg tgcgcggcag aaccggtttt gaatcagcgg actacccgca
    17281 aggccgctgg ttgcgcgaag cctgggaagt ggcgcagtca gtgccgacaa aagccgtcgt
    17341 tgaagcagga tttaaaggtg tggagattcg tgaggagctg acccgacggc ggattgcggc
    17401 ggtagccagc tggaaggaac aacgttgccc aaagcctgat taacttttta aattcagtat
    17461 attgcagaaa tcccttaggt cggataagac gcacaagcgt catatccgac actatctctc
    17521 aatcaaaaga acacgacgta caccgcagcc gccacaataa agcgataaat ggcgaacggg
    17581 ataaacgaaa tgcgcttaat caattgcagg aaggttttaa tcgctatcag cgccaccaca
    17641 aaagcggtga taaacccaac ggcaaacatc gggatatcgc cggtagtcag gaagccccag
    17701 cttttgtaga gatcgagcgc cgttgcgccc atcatcatcg gcaccgccag caggaacgag
    17761 aactcggaag cagcgtaacg gctcaccccc atcagcatcc cacctgaaat ggtcgccccg
    17821 gaacgggaga aacccggcca cagcgccaga cactggaaac agccaatcat aaacgcctga
    17881 cgataggtca tatcatcaag acccggcgca cgcggctctt tcggcttcag gcattcggca
    17941 gcaatcagca acagaccgcc aacgaccagt gcatacatga catttatcgg gttaaacaat
    18001 gatttaatcg tgtcgtggaa caacagcccc agtaccaccg ccggaatcat ccccagcaaa
    18061 atgtggatca gcgttaaacg acctttgttt tctccttcgt gctgcaacgg gcggccaaag
    18121 tggatgccaa tcaggccaaa cagacgccgc cagaacatca ctactaccgc cagaattgat
    18181 cctaactgga tcacgacttc aaaggttttc gccgtgtcgc cctcaaaccc caacaagtga
    18241 ccgacaataa tcatatggcc cgtgctggat accggcagaa attctgtcaa tccttcgacc
    18301 acacccaata ttgccgctat cagcagcgag tgcatatcgc tcatcaataa acccctaaat
    18361 tataaaaatg taacgcttgt ccgaactact gcagtatgac caggttataa tcgtttggtt
    18421 taacagctgt aaaattaatt attttctttc agattattgc cacgctcaat gattacgcca
    18481 acattcgccg cccgcgccac tgcgcctggc ttgctgagtt tgatacgcac ccacggcgag
    18541 ttgaagcgtg ctaacagcag ttccgccacc tcttcagcca cgcgttccac cagcgcaaaa
    18601 cgcgccccct cgacgtggct gaccaccgtt tctgcaatgt cagcgtaact gaggcaatcc
    18661 gccacatcat cacttttcgc cgctttacgg ttatcccacg ccatttcgat atcgaacact
    18721 aacttctgtt cgatggtctg ttcccagtcg taaacaccaa tagtggtgat taccgaaagt
    18781 tgctctataa atacaatatc catcacgtcc tgcctgcttt ttggctaacc ggataccact
    18841 tccggcgaaa tgtgcgtatt atccacagat tcatcgttga acacgaattt tcaaaacgga
    18901 acagcttatg agtgcaatcg cgcctggaat gatcctcatc gcgtacctct gcggctccat
    18961 ttccagtgcc attctggttt gccgcttgtg tgggttaccc gatccgcgaa ccagcggctc
    19021 cggcaatcca ggcgcaacca atgtgttacg tatcggtggc aagggagcag ccgtagcagt
    19081 actgattttc gacgttctga aaggaatgtt gcccgtctgg ggcgcgtatg aattaggtgt
    19141 cagccccttc tggctaggct taattgccat cgccgcctgt cttggacaca tctggcccgt
    19201 tttcttcggt tttaaaggag gaaaaggcgt tgctaccgct tttggtgcca tcgcaccaat
    19261 tggctgggat ctcactggag taatggcggg aacctggtta ctgaccgtgc tattgagtgg
    19321 ttactcgtcg ctgggagcga ttgtcagtgc actgattgct ccgttttatg tctggtggtt
    19381 taagccacaa ttcaccttcc cggtttcgat gctctcttgc ctgatcctgc tgcgtcatca
    19441 tgacaacatc cagcgtctgt ggcgtcgcca ggagacaaaa atctggacga aattcaaaag
    19501 aaagcgcgaa aaggatcccg agtgatttct ggtggatcta catgacctga tagccttcgt
    19561 cgggcttgcc cagccgttgc tggcaccatg ccgccagaaa ttccacacag acacgtaatt
    19621 tcatgctgcg atagagcggc tcccggtaaa cagcccagat attggcgctt tgtgcatact
    19681 ccggcaatac tcgcaccagt ttgccactct ccagaaacgg caacacatcc cactcggaac
    19741 gcagcataat ccctttgccc tccagcgccc attgcaacac aatctcgccg ctattggagg
    19801 aaagatgtcc gcttaccttc accgattttt tctcctgacc gttccccaac tcccatattc
    19861 cgtgggtcat atcgcgctct ttggtcacca ggcagtcatg acgacttaat tcctgtaagg
    19921 attgtggctg cggatatttt tgcagatact caggtgctgc gcataatatt cttttatttt
    19981 ttgtcaaaag atgcgcaata taataatcag gaattgcgtc attaatacga atatccagat
    20041 caatattatc ctgcactaaa tcaatttgtc gatcgaacaa ttcaaaatgc acctgtaact
    20101 caggataatt gcgcatcagt tcggtaatag ctggcgcaat atggctgcgc ccaaaaccaa
    20161 aactgcaacc aatgcggatc atcccctccg ggcgcgtttt gatttgcgtg acgtcatcga
    20221 ccagtcgctg atattgggtg aggatttcca gcgcatgttc gtaacaacgt tggccacttt
    20281 cagtcagcgc cacgccgcga gcggagcggt tcagcagcgt tgttgccagc gtattttcaa
    20341 ggatttggat ccgcttggtg acaaatgcag gcgtttgccc aagcgtcgcc gctgcagcac
    20401 taaaactccc gctatggacg atttccacca gtacctgcaa gtctttggct aaaggccagc
    20461 tatttagcat tgttaaatat ccgcagtttt gataaacgca gtgtatttcg caaaacatta
    20521 ccattccctg ctctggcgca atattcgttc ttattttcgc gttgattcac gaactgttaa
    20581 ttacatattc acggtggcaa aaaatataaa accacatttt tagtggtagt ttgtggcggt
    20641 gaatttttcc agacaaatac ataaactgga gttgccatga tgagcgaaag taataagcaa
    20701 caggcagtga ataagttgac ggagattgtc gctaacttta ccgccatgat ttctacccga
    20761 atgcctgatg acgtggtgga taaactaaaa cagctaaagg atgccgaaac atcgtcgatg
    20821 ggaaaaatca tctaccacac gatgttcgat aacatgcaaa aagcgatcga cctgaatcgt
    20881 cctgcctgtc aggacaccgg cgaaatcatg ttttttgtta aggtcggttc ccgtttccca
    20941 ctgcttggcg agctgcaaag catactcaaa caagccgtgg aagaggcaac cgtcaaagcg
    21001 ccactgcgtc acaatgcggt agaaattttt gacgaagtaa acaccggcaa aaataccggc
    21061 agcggcgtac cgtgggtcac ctgggatatc gtccccgacg gtgacgatgc ggaaatcgaa
    21121 gtttacatgg caggcggcgg ctgcacgcta cctggccgat cgaaagtgtt aatgccgtca
    21181 gaaggctacg aaggcgtagt gaaattcgtc ttcgaaaata tctccaccct cgccgtaaac
    21241 gcctgtccgc cggtactggt gggcgttggc atcgctacct cggtggaaac cgccgcagtg
    21301 ctctcgcgaa aagccatttt gcgcccgatt ggcagccgcc accccaatcc gaaagcggca
    21361 gagctggagc tacgcctgga agaaggactc aaccgtttgg ggattggtcc acaagggctg
    21421 actggcaaca gttcagtgat gggcgtgcat atcgaatctg ccgctcgcca tccgtcaacc
    21481 atcggcgttg ctgtttctac cggctgctgg gcgcatcgtc gcggcacact gctggttcat
    21541 gccgatctca cctttgaaaa tctgtctcac acccggagcg cgttatgaaa aagatcctga
    21601 caaccccgat caaagctgaa gatctgcaag atattcgcgt cggcgatgtg atctacctga
    21661 ccggtacgct ggtgacctgc cgtgacgttt gtcaccgtcg cttgatcgaa ctgaaacgtc
    21721 cgatccctta cgatctcaac ggcaaagcga ttttccacgc tggccccatc gtgcgcaaaa
    21781 acggcgacaa atgggagatg gtatccgtcg gcccgacaac cagtatgcgt atggaaagtt
    21841 ttgaacgtga atttatcgag cagaccggcg tgaaactggt ggtcggcaaa ggcggaatgg
    21901 ggccgctgac cgaagaaggc tgccagaaat tcaaggcgct gcatgtgatt ttcccggctg
    21961 gctgtgcggt actggcggca actcaagtgg aagagattga agaagtgcac tggacagaac
    22021 tcgggatgcc agagtcgctg tgggtctgcc gggtcaaaga gtttggcccg ctgattgtct
    22081 ctatagatac ccacggcaac aacctgatag ccgaaaataa aaagctgttc gccgaacgcc
    22141 gcgatcccat cgtggaagag atctgcgagc acgtccacta catcaaataa ccctcacgga
    22201 gaggctcgcc cctctccttt ttcgcaggca taacacgatg aaaccttcca ctgaatggtg
    22261 gcgatacctt gcgccgctgg cggtcatcgc cattattgct ctacttccgc ttcccgcagg
    22321 gctggagagt catacctggc tctactttgc cgtttttact ggcgtgatcg ttggactgat
    22381 cctcgaaccc gtgccgggtg ccgtggtggc gatggtgggt atatccatca tcgccattct
    22441 ttcgccgtgg ctgctgttta gcccggagca gctcgcccag ccaggtttta agttcaccgc
    22501 caaatccctc tcctgggcgg tttctggttt ttctaattca gttatctggc ttattttcgc
    22561 cgcctttatg tttggtacgg gctatgaaaa aaccgggctt ggacgtcgca tcgcgctgat
    22621 tctggtgaaa aaaatggggc atcgcacgct gtttctcggc tatgcagtga tgttctccga
    22681 gctgatactc gcgcctgtaa caccgtccaa ctcggcgcgt ggtgcgggga ttatctatcc
    22741 catcatccgt aacctgccac cgctctatca atcacaacca aacgacagca gttcgcgcag
    22801 cattggctcg tacatcatgt ggatggggat tgttgccgac tgcgtgacca gcgccatttt
    22861 cctgacggcg atggctccaa atttgctgtt aattggactg atgaaaagcg catctcacgc
    22921 catgctaagc tggggcgact ggttcctcgg gatgttgccg ctcagcattt tactggtttt
    22981 gctggttccc tggctggctt acgtgctgta cccgccggta ctgaagtctg gcgatcaggt
    23041 gccgcgctgg gcagagacgg aactgcaggc aatgggcccg ctctgttcgc gtgaaaaacg
    23101 gatgctgggg ctgatggtag gcgcactggt gttgtggatt tttggcggtg attatatcga
    23161 tgccgcgatg gtcggttaca gcgtggtggc gctgatgctg cttctgcgca ttatcagttg
    23221 ggacgacatt gtcagtaata aagcggcgtg gaacgttttc ttctggctgg cctcgcttat
    23281 caccctcgct accggactca acaacaccgg ttttattagc tggtttggca aactgttagc
    23341 aggcagctta agcggttatt cgccaacgat agtgatggtg gcgttgattg tggtctttta
    23401 tctgctgcgc tacttttttg ccagcgccac agcgtatacc tccgctctcg caccgatgat
    23461 gattgccgcc gcgctggcga tgccggaaat cccgctgccg gtgttctgcc tgatggttgg
    23521 tgcggcaatt ggtctgggga gcattcttac accatacgcc accggaccca gtccgattta
    23581 ctacggcagt ggttatctgc caacggcgga ttactggcga ctgggggcga tttttgggct
    23641 gatattcctc gtattgctgg tgattaccgg cttactgtgg atgcccgtgg tgttgcttta
    23701 agtgaggacg gtgccggaaa ttgctctccg gcacccaata gttttacgcg gccggtaact
    23761 ctgccagtgg ccagcgcgga cgcacactca cgccgagatc cgccgtcgcg cctgctttaa
    23821 accgcaccat tccggcatag gcgatcatcg caccgttatc cgtacaaaat tccggacgcg
    23881 cgtagaacac ttcgccacgg cgttttttca tcatttccgc cagtttcgcc cgcaacgtgc
    23941 ggttagcact cacgccgcct gccatgacca gtcgcttaaa gcccgtctga tccagtgctc
    24001 gcttacactt aatcatcaac gtatcgacca ctgcatcttc aaaggcgcgg gcgatatcgg
    24061 cacgcgtctg atcgtcagtg ccgttgtcac gtatggtatt tgccgcgaag gttttcagac
    24121 cagaaaagct gaaatccagc cccggacggt cggtcatcgg acgcgggaaa acaaagcgcc
    24181 cggcagtacc ctgagccgcc attttagaca gtaacggtcc gccaggataa tccagcccca
    24241 gcagcttcgc ggttttatca aacgcttcac cagcagcatc atcgatagac tcgccgagca
    24301 gctcgtactg accaatgcca gtcacgctga ttaactgcgt atgaccgccg gaaaccagca
    24361 gcgcgacaaa cggaaattcc ggtgggttat cttccagcat cggcgctaac agatgtcctt
    24421 ccatatgatg taccgggatt gccggaacgt cccaggcaaa cgccagagaa cgccccacgg
    24481 tcgcgccaac cagcagtgcg ccgactaatc ctgggcctgc ggtataggcc acagcatcaa
    24541 tgtcttttgc cgttaaacca gactccttta gcgcctcctg gatcaacggt acggttttac
    24601 gcacgtgatc gcgggaggcc agttcaggca cgacgccgcc gtagtcagcg tgcaatttca
    24661 cctgactata caattggttg gctaacaaac ctttttcatc gtcgtaaatg gcgatgccgg
    24721 tttcatcgca ggaagtttca atacccagta cacgcatgac ttgttttacc tcgctttatt
    24781 accgcgcagt gtaggaccaa tgcgggttga tgtaaaactt tgttcgcccc tggagaaagc
    24841 ctcgtgtata ctcctcaccc ttataaaagt ccctttcaaa aaaggccgcg gtgctttaca
    24901 aagcagcagc aattgcagta aaattccgca ccattttgaa ataagctggc gttgatgcca
    24961 gcggcaaacc gaattaatca aaggtgagag gcacatgccg gtaattaaag tacgtgaaaa
    25021 cgagccgttc gacgtagctc tgcgtcgctt caagcgttcc tgcgaaaaag caggtgttct
    25081 ggcggaagtt cgtcgtcgtg agttctatga aaaaccgact accgaacgta agcgcgctaa
    25141 agcttctgca gtgaaacgtc acgcgaagaa actggctcgc gaaaacgcac gccgcactcg
    25201 tctgtactaa ttccccgaga gcgttgctct ccgatcagac cgagttgtag ttgtaaggcc
    25261 gtgcttccga aaggaatgcg cggcttattt tcgtttatga attgctaaaa atcggggcct
    25321 atggctggac gaatcccacg cgtattcatt aatgatctgc tggcacgcac tgacatcgtc
    25381 gatctgatcg atgcccgtgt gaagctgaaa aagcagggca agaatttcca cgcgtgttgt
    25441 ccattccaca acgagaaaac cccgtcattc accgttaacg gtgagaaaca gttttaccac
    25501 tgctttggat gtggcgcgca cggcaacgcg atcgacttcc tgatgaacta cgacaagctc
    25561 gagttcgtcg aaacggtcga agagctggca gcaatgcaca atcttgaagt gccatttgaa
    25621 gcaggcagcg gccccagcca gatcgagcgc catcagaggc aaacgcttta tcagttgatg
    25681 gacggtctga atacgtttta ccaacaatct ttacaacaac ctgttgccat gtctgcgcgc
    25741 cagtatctgg aaaaacgcgg attaagccac gaggttatcg ctcgctttgc gattggtttt
    25801 gcgccccccg gctgggacaa cgtcctgaag cggtttggcg gcaatccaga aaatcgccag
    25861 tcattgattg atgcgggcat gttggtcact aacgatcagg ggcgcagtta cgatcgtttc
    25921 cgcgagcggg tgatgttccc cattcgtgat aaacgcggtc gggtgattgg ttttggcgga
    25981 cgcgtgctgg gcaacgatac ccccaaatac ctgaactcgc cggaaacgga cattttccat
    26041 aaaggccgcc agctttacgg tctttatgaa gcgcagcagg ataacgctga acccaatcgt
    26101 ctgcttgtgg tcgaaggcta tatggacgtg gtggcgctgg cgcaatacgg cattaattac
    26161 gccgttgcgt cgttaggtac gtcaaccacc gccgatcaca tacaactgtt gttccgcgcg
    26221 accaacaatg tcatttgctg ttatgacggc gaccgtgcag gccgcgatgc cgcctggcga
    26281 gcgctggaaa cggcgttgcc ttacatgaca gacggtcgtc agctacgctt tatgtttttg
    26341 ccggatggcg aagaccctga cacgctggta cgaaaagaag gtaaagaagc gtttgaagcg
    26401 cggatggagc aggcgatgcc actctccgca tttctgttta acagtctgat gccgcaagtt
    26461 gatctgagta cccctgacgg gcgcgcacgt ttgagtacgc tggcactgcc actgatatcg
    26521 caagtgccgg gcgaaacgct gcgaatatat cttcgtcagg aattaggcaa caaattaggc
    26581 atacttgatg acagccagct tgaacgatta atgccaaaag cggcagagag cggcgtttct
    26641 cgccctgttc cgcagctaaa acgcacgacc atgcgtatac ttatagggtt gctggtgcaa
    26701 aatccagaat tagcgacgtt ggtcccgccg cttgagaatc tggatgaaaa taagctccct
    26761 ggacttggct tattcagaga actggtcaac acttgtctct cccagccagg tctgaccacc
    26821 gggcaacttt tagagcacta tcgtggtaca aataatgctg ccacccttga aaaactgtcg
    26881 atgtgggacg atatagcaga taagaatatt gctgagcaaa ccttcaccga ctcactcaac
    26941 catatgtttg attcgctgct tgaactgcgc caggaagagt taatcgctcg tgagcgcacg
    27001 catggtttaa gcaacgaaga acgcctggag ctctggacat taaaccagga gctggcgaaa
    27061 aagtgattta acggcttaag tgccgaagag cgatcgggaa gcccccgaca gccgcactga
    27121 gaggcagcgg caaatatata agtacgccct cgtaattatc gttggcggta aacaaccgtt
    27181 ggatttcagc gttaacggct gaaggacatc gggtcaatcg cccaacacca acctcatgaa
    27241 ataagtgtgg ataccgtctt atggagcaaa acccgcagtc acagctgaaa cttcttgtca
    27301 cccgtggtaa ggagcaaggc tatctgacct atgccgaggt caatgaccat ctgccggaag
    27361 atatcgtcga ttcagatcag atcgaagaca tcatccaaat gatcaacgac atgggcattc
    27421 aggtgatgga agaagcaccg gatgccgatg atctgatgct ggctgaaaac accgcggacg
    27481 aagatgctgc cgaagccgcc gcgcaggtgc tttccagcgt ggaatctgaa atcgggcgca
    27541 cgactgaccc ggtacgcatg tacatgcgtg aaatgggcac cgttgaactg ttgacccgcg
    27601 aaggcgaaat tgacatcgct aagcgtattg aagacgggat caaccaggtt caatgctccg
    27661 ttgctgaata tccggaagcg atcacctatc tgctggaaca gtacgatcgt gttgaagcag
    27721 aagaagcgcg tctgtccgat ctgatcaccg gctttgttga cccgaacgca gaagaagatc
    27781 tggcacctac cgccactcac gtcggttctg agctttccca ggaagatctg gacgatgacg
    27841 aagatgaaga cgaagaagat ggtgacgacg ataccgccga tgatgacaac agcatcgacc
    27901 cggaactggc tcgcgaaaaa tttgcggaac tgcgcgctca gtacattgta acgcgtgaca
    27961 ccatcaaagc gaaaggccgc agtcacgctg ccgctcagga agagatcctg aaactgtctg
    28021 aagtattcaa acagttccgc ctggtgccga agcagtttga ctacctggtc aacagcatgc
    28081 gcgtcatgat ggaccgcgtt cgtacgcaag aacgtctgat catgaagctc tgcgttgagc
    28141 agtgcaaaat gccgaagaaa aacttcatta ccctgtttac cggcaacgaa accagcgata
    28201 cctggttcaa cgcggcaatt gcgatgaaca agccgtggtc ggaaaaactg catgatgtct
    28261 ctgaagaagt gcatcgcgcc ctgcagaaac tgcagcagat tgaagaagaa accggcctga
    28321 ccatcgagca ggttaaagat atcaaccgtc gtatgtccat cggtgaagcg aaagcccgcc
    28381 gtgcgaagaa agagatggtt gaagcgaact tacgtctggt tatttctatc gccaagaaat
    28441 acaccaaccg tggcttgcag ttccttgacc tgattcagga aggtaacatc ggcctgatga
    28501 aagcggttga taaattcgaa taccgccgtg gttacaagtt ctccacctac gctacctggt
    28561 ggatccgtca ggcgatcacc cgctctatcg cggatcaggc gcgcaccatc cgtattccgg
    28621 tgcatatgat tgagactatc aacaagctca accgtatttc tcgccagatg ctgcaagaga
    28681 tgggccgtga accaacgccg gaagaactgg ctgaacgcat gctgatgccg gaagacaaga
    28741 tccgcaaagt gctgaagatc gccaaagagc caatctccat ggaaacgccg atcggtgatg
    28801 atgaagattc gcatctgggg gatttcatcg aggataccac cctcgagctg ccgctggatt
    28861 ctgcgaccac cgaaagcctg cgtgcggcaa cgcacgacgt gctggctggc ctgaccgcgc
    28921 gtgaagcgaa agttctgcgt atgcgtttcg gtatcgatat gaacaccgac cacacgctgg
    28981 aagaagtggg taaacagttc gacgttaccc gcgaacgtat ccgtcagatc gaagcgaagg
    29041 cgctgcgcaa actgcgtcac ccgagccgtt ctgaagtgct gcgtagcttc ctggacgatt
    29101 aatcggtagg ccggatcagg tgttacgccg cacccggcac tagtccctcc gcacaaacgc
    29161 caccttttcg gtggcgtttt tatcgcccac gcaccaccag cgcctggtcc agctcgcgat
    29221 acgcttcaac cagtttctcc agtgaaacgc gacttaaacc gctgggattt ggcagcaccc
    29281 aaatctgcgt cgaaccaatg gtgagcgttt gtttccccca ctgtgcaccg cgctggctga
    29341 atccctgttc atatgcttgt ttgcccagaa tcgccaacgc ctgcggctga taatcttcaa
    29401 ttttttcaat cagcttacgc ccgcctgcgt gtagctcctg ctttgaaact tcattggctt
    29461 gcaccgttgg acggtctacc agtttggtga cgccacaacg ataatccagc agatgctgtg
    29521 cctcctgcgg cttcaactga cggtcggtaa acccggcctg atatatcacc ttccagaagc
    29581 gatttgccgg atgagcaaag ggaaaaccag tcccggcgga tgaaagacca gggttgatac
    29641 cgcaaaacac gacccgtaac cctggagcca aaatatcctc aaccatattt actcctttct
    29701 aacatcacca ggaaaagtat aacggattga aaatacattg tttataaaaa cagcaggcgc
    29761 gcggtaatgg ctggattgcg acacggagtt actttataat ccgctaccat ggccccttag
    29821 ctcagtggtt agagcaggcg actcataatc gcttggtcgc tggttcaagt ccagcagggg
    29881 ccaccagaca tagcaaaggc tgacgagaaa tcgtcagcct ttttcttttt atatatccgt
    29941 tactttgcgt gccagtaagc cgccgcacgt acccgctgtg ggtcatactg ttccgtttca
    30001 aagcggcggc ttaaattctt aacgactttg ccttcgccgg ttatccagat gaagtaatca
    30061 tcggcaggga tttgcatctg cgccagacgc gcatctaccg cctgctcatc atgtgccagc
    30121 cattcgatat taaaaccatc aaggtgcgcg agataatcct gacaggcgtt atcccgcacg
    30181 ctaaccagcg cactaacttg cggtttaaca gcaagtttgc tcaacgtttc caggcggcgg
    30241 cgcagtgcgg gcattccgga ttcatcgcag acatacagct gatacgcgta atcttccggc
    30301 accaccagcg aaccgcgcgg acctgccacc gtaagtttat cgcccggttt cgcctgcatc
    30361 gcccagccgc tggcgacccc accgtcgtga ataaaaaaat caatcgccag ttcatggcgt
    30421 agttcgtcat acagcggcgt atagtcacgc gacggtgggc gtgatccttc cggccagacg
    30481 atgccctctt ccgttaccgt tggcggcaca aagtgagcgt caggttgagg aaagaagagt
    30541 ttgctgtgat cgtcaaagcc gcgcgatgta aaaccgtcca gcgcctcgcc gccgaggaca
    30601 atgcgctgaa aaccggcgct gatgcgctca acgcgtagca cagtcagttc acggaagcgc
    30661 agatcattgc gaacgcgctg tgggtagcgg ggggtgttat tcattgtt
//
LOCUS       DAFGPF010000054        30515 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFGPF010000054 DAFGPF010000000
VERSION     DAFGPF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30515
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.054"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            158..1699
                     /gene="istA"
                     /locus_tag="LSX49_002690"
     CDS             158..1699
                     /gene="istA"
                     /locus_tag="LSX49_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family transposase"
                     /protein_id="HBL7169085.1"
                     /translation="MPTVPISMRKLKEILRLKYGVGLSHRQIGRSLAISPSVVSRYAN
                     RAAQLGIKQWPLPTGWDDTKLKHAFLQTQVKMKKHSLPDWATVHRELRNKCVTLQLLW
                     EEYCERNPGGFYSYNHYCRMYREWLKTTSPSMRQVHKAGEKLFVDYCGPTVGVTDPET
                     GEIRTAQVIVAVLGASSYTWAEATWSQQLEDWVMSHVRCFQWLGGVPELVVPDNLKSA
                     TSRACKYDPDVNPTYQQMLEHYNVAVLPARPRKPKDKAKAEVGVQVVERWIMARIRHE
                     IFYSLASLNQRIRELLERLNNKIMQKLGYSRAELFIQLDKPALKPLPEASYSYTLVKK
                     VRVHADYHVEIDKHYYSVPCSLLGQQLEAWISGELVRLFNQGQEVAVHPRKRTYGYST
                     RNEHMPEAHRQHATWTPERLLEWAGHIGSETHSYVLHILNSRPHPEQSYRFCLGLLNL
                     HKKYSKARLNAACARALKTKVWRLSGIKSILEKGLDKQPVQDPKPDLLSTMEHENVRG
                     SEYYH"
     gene            1714..2460
                     /gene="istB"
                     /locus_tag="LSX49_002691"
     CDS             1714..2460
                     /gene="istB"
                     /locus_tag="LSX49_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family helper ATPase
                     IstB"
                     /protein_id="HBL7169086.1"
                     /translation="MNHLYEQLTALKLTGFRDALKKQLAQPGTYQELGFEERLSLLTA
                     EELTCRENRKAERLIKHARFRLNAELSKLDYRNNRGLDRALIRSLSQGNWLTLKQNIL
                     LTGATGSGKTFLACALGHNACRQGYKVYYYRLKALMEQCYQGHADGRYSKLLTRLNNS
                     DLLLLDDWGLEPLSSEQRSDLLEIVDLMYQRGSIIVVSQLPVENWYKMIGDSTHADAI
                     LDRLVHGSIKIELKGESMRKIQSPLTEGDQ"
     gene            2543..2893
                     /locus_tag="LSX49_002692"
                     /pseudo
     CDS             2543..2893
                     /locus_tag="LSX49_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310826.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2909..3319
                     /locus_tag="LSX49_002693"
     CDS             2909..3319
                     /locus_tag="LSX49_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169087.1"
                     /translation="MKTFIKTLLVAVTILFSVFAAAKQVKLPNNIKYVNTTEAFSCTE
                     IDGMNCQTKNPFNYKDNSYVFVLERGGAWCYDYTVSVLNLKTGKEQMLEYKDNQLCSG
                     SNKPFFEIKNGVPTVGVIDTSGKPVVVALDKLKT"
     gene            3540..4358
                     /locus_tag="LSX49_002694"
     CDS             3540..4358
                     /locus_tag="LSX49_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBL7169088.1"
                     /translation="MRLTSRFGYVNQIRRDRPLTHEELMHHVPGIFGEDRHTSCSERY
                     TYIPTITVLESLQREGFHPFFACQTRVRDPDRREYTKHMLRLRRNGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLILPPPARQALAQAALTYRYGDEHRPVTTADILTPRRREDYGKDLWS
                     TYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESLR"
     gene            4358..4603
                     /locus_tag="LSX49_002695"
     CDS             4358..4603
                     /locus_tag="LSX49_002695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169089.1"
                     /translation="MQHVPEGVIQAPESPDAPEALPGCRSISDDDLCAWCTRLLYRPG
                     EISLCRLSTGNGIWPSVCDRNGYAYGCPEFQPNIIHP"
     gene            4697..5170
                     /locus_tag="LSX49_002696"
     CDS             4697..5170
                     /locus_tag="LSX49_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBL7169090.1"
                     /translation="MKTLSQNTTSSACAPETGLQQLVATIVPDEQRISFWPQHFGLIP
                     QWVTLEPRVFGWMDRLCENYCGGIWNLYTLNNGGAFMAPEPDDYDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRIID"
     gene            5186..5662
                     /locus_tag="LSX49_002697"
     CDS             5186..5662
                     /locus_tag="LSX49_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HBL7169091.1"
                     /translation="MQQISFLPGEMTTRERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEHGLL"
     gene            5725..5946
                     /locus_tag="LSX49_002698"
     CDS             5725..5946
                     /locus_tag="LSX49_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBL7169092.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            5965..6609
                     /locus_tag="LSX49_002699"
     CDS             5965..6609
                     /locus_tag="LSX49_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of toxin-antitoxin stability system"
                     /protein_id="HBL7169093.1"
                     /translation="MSRIITTTVYTLHELSSTAQEKARDWYRQHHADSNWYENVYEDF
                     RAVCGIFGIDLRQRVFRLSNGRFMEEACIWFSGFCSQGDGACFEGRWHWQPATARRLR
                     EYATQDHELHRIADALQAVQKRNFWQLQAEIHHRGRYCHPYSMDITVTRNSPTGQAMT
                     ADAEAAVSEALRDLAFWLYRQLENEYDRLTSDAAVDEALLINEYTFTEAGLRAG"
     gene            6625..6993
                     /locus_tag="LSX49_002700"
     CDS             6625..6993
                     /locus_tag="LSX49_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HBL7169094.1"
                     /translation="MSDKLHETNYPDDHNDRLWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCKAD
                     TLSSCGYVYLAVYPTPEMKN"
     gene            7082..7456
                     /gene="cbtA"
                     /locus_tag="LSX49_002701"
     CDS             7082..7456
                     /gene="cbtA"
                     /locus_tag="LSX49_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HBL7169095.1"
                     /translation="MKTLPVLPGQAASSRPSPVEIWQILLSRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSACTRSQLINSIDILRARRATG
                     LMTSDNYRTVNNITLGKYPEAK"
     gene            7453..7647
                     /locus_tag="LSX49_002702"
     CDS             7453..7647
                     /locus_tag="LSX49_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169096.1"
                     /translation="MMTLEADSVNVQALDMGHIVVDIDGVNITELINKAAENGYSLRV
                     VDDRDSTETPATYASPHQLL"
     gene            7660..7773
                     /locus_tag="LSX49_002703"
     CDS             7660..7773
                     /locus_tag="LSX49_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HBL7169097.1"
                     /translation="MQGIVPLTTETALLSCIKQAREDVLTLRHLQLLHQNR"
     gene            complement(8062..8208)
                     /locus_tag="LSX49_002704"
                     /pseudo
     CDS             complement(8062..8208)
                     /locus_tag="LSX49_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            8262..8444
                     /locus_tag="LSX49_002705"
     CDS             8262..8444
                     /locus_tag="LSX49_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HBL7169098.1"
                     /translation="MNHPVIGVVTKADLASMEQISLVTSWLREAGAHNVLVTSAVNNN
                     GVTELFALLHTEEGCC"
     gene            complement(8545..8874)
                     /locus_tag="LSX49_002706"
     CDS             complement(8545..8874)
                     /locus_tag="LSX49_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HBL7169099.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(9046..10104)
                     /locus_tag="LSX49_002707"
     CDS             complement(9046..10104)
                     /locus_tag="LSX49_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL7169100.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIA
                     PASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQ
                     QILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLDNHHDLKVLETPIYGYVWLNME
                     TAHQLELLSNLICRALRK"
     gene            complement(10302..10775)
                     /gene="sbmC"
                     /locus_tag="LSX49_002708"
     CDS             complement(10302..10775)
                     /gene="sbmC"
                     /locus_tag="LSX49_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HBL7169101.1"
                     /translation="MNYEIKQEDKRTVAGFHLVGPWEQMVKKGFEQLMMWIDSKNIVP
                     KEWVAVYYDNPDETPAEKLRCDTVVTVPNNFTLPENSEGVILTEISGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH"
     gene            complement(10894..12060)
                     /gene="dacD"
                     /locus_tag="LSX49_002709"
     CDS             complement(10894..12060)
                     /gene="dacD"
                     /locus_tag="LSX49_002709"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HBL7169102.1"
                     /translation="MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGREEEARKLLR
                     WGQQNFTTVQILHRGKKVGTERIWYGDKENIALGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            12269..13696
                     /gene="sbcB"
                     /locus_tag="LSX49_002710"
     CDS             12269..13696
                     /gene="sbcB"
                     /locus_tag="LSX49_002710"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HBL7169103.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDNEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNVFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVILVDLAGDISPLLELDS
                     DTLRERLYTAKADLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYADELQML
                     AQQYADDKEKVALLKALWQYAEEIV"
     gene            complement(13807..14265)
                     /gene="tnpA"
                     /locus_tag="LSX49_002711"
     CDS             complement(13807..14265)
                     /gene="tnpA"
                     /locus_tag="LSX49_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element IS200C family
                     transposase"
                     /protein_id="HBL7169104.1"
                     /translation="MGNEKSLAHTRWNCKYHIVFAPKYRRQVFYREKCRAIGCILRKL
                     CEWKSVRILEAECCADHIHMLVEIPPKMSVSGFMGYLKGKSSLMPYEQFGDLKFKYRN
                     REFWCRGYYVDTVGKNTAKIQDYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
     gene            complement(14482..15840)
                     /gene="plaP"
                     /locus_tag="LSX49_002712"
     CDS             complement(14482..15840)
                     /gene="plaP"
                     /locus_tag="LSX49_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HBL7169105.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQIVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(15830..15892)
                     /gene="yoeI"
                     /locus_tag="LSX49_002713"
     CDS             complement(15830..15892)
                     /gene="yoeI"
                     /locus_tag="LSX49_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HBL7169106.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            complement(16107..17036)
                     /locus_tag="LSX49_002714"
     CDS             complement(16107..17036)
                     /locus_tag="LSX49_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7169107.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLAQEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDGKSAI"
     gene            complement(17082..17906)
                     /locus_tag="LSX49_002715"
     CDS             complement(17082..17906)
                     /locus_tag="LSX49_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7169108.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSG
                     IDSYLLRMEPELVCDSDDLDALMDADALVITLPARRSGPGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            complement(17989..18243)
                     /gene="yoeB"
                     /locus_tag="LSX49_002716"
     CDS             complement(17989..18243)
                     /gene="yoeB"
                     /locus_tag="LSX49_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HBL7169109.1"
                     /translation="MKLIWSEESWDDYLYWQEADKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHLLVYAVTDDSLLIAACRYHY"
     gene            complement(18240..18491)
                     /gene="yefM"
                     /locus_tag="LSX49_002717"
     CDS             complement(18240..18491)
                     /gene="yefM"
                     /locus_tag="LSX49_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HBL7169110.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSDKGTEKDIIE"
     gene            18774..18824
                     /gene="hisL"
                     /locus_tag="LSX49_002718"
     CDS             18774..18824
                     /gene="hisL"
                     /locus_tag="LSX49_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HBL7169111.1"
                     /translation="MTRVQFKHHHHHHHPD"
     misc_feature    18800..18923
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            18970..19869
                     /gene="hisG"
                     /locus_tag="LSX49_002719"
     CDS             18970..19869
                     /gene="hisG"
                     /locus_tag="LSX49_002719"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBL7169112.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     gene            19875..21179
                     /gene="hisD"
                     /locus_tag="LSX49_002720"
     CDS             19875..21179
                     /gene="hisD"
                     /locus_tag="LSX49_002720"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBL7169113.1"
                     /translation="MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVK
                     TRGDEALREYSAKFDKTTVTALKVSADEIAAASERLSDELKQAMAVAVKNIETFHTAQ
                     KLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLC
                     SPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDAD
                     MARRVAEAVERQLAELPRAETARQALSASRLIVTNDLAQCVEISNQYGPEHLIIQTRN
                     ARDLVDSITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNVLKEQA"
     gene            21176..22246
                     /gene="hisC"
                     /locus_tag="LSX49_002721"
     CDS             21176..22246
                     /gene="hisC"
                     /locus_tag="LSX49_002721"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBL7169114.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDA
                     ILYCPPTYGMYSVSAETIGVECRTVPTLENWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAER
                     EYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            22246..23313
                     /gene="hisB"
                     /locus_tag="LSX49_002722"
     CDS             22246..23313
                     /gene="hisB"
                     /locus_tag="LSX49_002722"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HBL7169115.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQ
                     KAGYKLVMITNQDGLGAQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDREALNWPMIGE
                     QLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            23313..23903
                     /gene="hisH"
                     /locus_tag="LSX49_002723"
     CDS             23313..23903
                     /gene="hisH"
                     /locus_tag="LSX49_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBL7169116.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIEED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGTAGAKLLKNFLEM"
     gene            23903..24640
                     /gene="hisA"
                     /locus_tag="LSX49_002724"
     CDS             23903..24640
                     /gene="hisA"
                     /locus_tag="LSX49_002724"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBL7169117.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPAKRQIPLIKTLVTGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVFLYEEVCARYPQVAFQSSGGIGDINDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNA"
     gene            24622..25398
                     /gene="hisF"
                     /locus_tag="LSX49_002725"
     CDS             24622..25398
                     /gene="hisF"
                     /locus_tag="LSX49_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBL7169118.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
                     DWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC"
     gene            25392..26003
                     /locus_tag="LSX49_002726"
     CDS             25392..26003
                     /locus_tag="LSX49_002726"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBL7169119.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TLESGKVTFFSRTKQRLWTKGETSGNILNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLATVIENLRKRHQ"
     gene            complement(26189..27166)
                     /gene="wzzB"
                     /locus_tag="LSX49_002727"
     CDS             complement(26189..27166)
                     /gene="wzzB"
                     /locus_tag="LSX49_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310855.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen chain length determinant protein
                     WzzB"
                     /protein_id="HBL7169120.1"
                     /translation="MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIAL
                     AIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQATPKVSDLQETLIGRFSSA
                     FSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVN
                     QELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQIQ
                     QTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSSYYQTRQNLLDIDNLDVDKLDIHA
                     YRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGVGIVLGRNALRNYNAK"
     gene            complement(27312..28478)
                     /gene="ugd"
                     /locus_tag="LSX49_002728"
     CDS             complement(27312..28478)
                     /gene="ugd"
                     /locus_tag="LSX49_002728"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HBL7169121.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGTIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            complement(28725..30131)
                     /gene="gndA"
                     /locus_tag="LSX49_002729"
     CDS             complement(28725..30131)
                     /gene="gndA"
                     /locus_tag="LSX49_002729"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBL7169122.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQRAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            complement(30228..>30515)
                     /locus_tag="LSX49_002730"
     CDS             complement(30228..>30515)
                     /locus_tag="LSX49_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL7169123.1"
                     /translation="SFMLIHALSFLNVNGFDQKYFMYCEDIDLCMRLKLSGVDLYYTP
                     HFDAIHYAQHENRRIFTKAFRWHIRSITRYILRKPILSYKNYRKITSELVK"
BASE COUNT         7857 a         7817 c         7500 g         7341 t
ORIGIN      
        1 ccatcgagat cgggtaataa catttgaaca gatcgctgaa taacatcgat ggagatcact
       61 tttgactcat tttgttattc agtgatctcc atcaatgtta ttggaacttc acaggtgtgt
      121 tgatctgtat cttttgccat tccggtaaag gatacctatg ccaacagttc caatttctat
      181 gagaaaactt aaagaaattc ttaggcttaa atacggtgtt ggactcagcc atcgacaaat
      241 tggtcgtagt cttgcaatct ccccttccgt tgtatccaga tatgctaatc gggcggctca
      301 acttggcata aagcagtggc ccttacctac aggatgggat gatacaaaac taaaacatgc
      361 gttccttcag acccaggtta agatgaagaa gcactctctg cctgactggg ctacagtaca
      421 ccgggaactg cgtaataaat gcgtgacgct gcagctactc tgggaagaat actgtgagcg
      481 taatccaggc ggtttttaca gctataacca ttactgccgg atgtaccgtg aatggctcaa
      541 aaccacttca ccatcaatgc gtcaggtaca taaagctggc gaaaaacttt tcgttgatta
      601 ctgtggacct accgttggcg ttaccgaccc tgagaccgga gaaataagaa ctgctcaggt
      661 catcgtagct gttctcgggg catcaagtta cacatgggca gaggccacct ggtctcagca
      721 gcttgaagac tgggtgatga gtcatgttcg ctgcttccag tggttgggtg gcgttcctga
      781 acttgttgtt ccggacaatc tgaaaagcgc cacatccagg gcatgtaagt atgatcctga
      841 cgttaaccct acctaccagc agatgcttga gcattataat gtcgcagttt tgcctgcgcg
      901 gccacgtaaa ccgaaagata aagccaaagc tgaagttggc gttcaggttg ttgaacgctg
      961 gatcatggcc cgaatcaggc atgagatctt ctacagcctt gcatcgctta atcagcgcat
     1021 tcgggagttg ctggaaagac tgaataacaa aataatgcag aagttgggtt attcacgtgc
     1081 agaactcttc atccagcttg ataaacccgc actgaagcct cttcctgaag ccagttacag
     1141 ttacaccctg gtgaagaaag tcagagttca tgccgattac cacgtggaaa tcgacaaaca
     1201 ttactactcg gttccatgtt cgctgttagg ccagcaactg gaagcatgga tctccggaga
     1261 actggtaaga ctcttcaatc aggggcagga ggttgctgtg cacccgcgca agcgtactta
     1321 tggctacagt acccgcaacg agcacatgcc tgaagctcat cgacagcatg ccacctggac
     1381 gccagagcgt cttctggaat gggcggggca cataggcagt gaaactcata gttatgtgct
     1441 tcatatactg aactctcgtc cacatccgga acaaagctat cgcttctgcc ttggactcct
     1501 gaaccttcat aaaaaataca gtaaagccag acttaatgca gcatgtgcaa gagctctgaa
     1561 aacaaaggta tggcgtctgt caggtattaa atcgatcctg gaaaaaggtc tggataaaca
     1621 acctgttcag gatccaaaac cagatctgtt atccacgatg gaacacgaaa acgtacgcgg
     1681 cagtgagtat taccactgat acgggatcca atgatgaatc atctttacga acaactgacc
     1741 gcacttaaac tcaccggctt ccgtgatgcg cttaaaaagc aacttgctca accgggcaca
     1801 taccaggagc tgggcttcga agaacgcctg tcattactga cagcagaaga actaacctgc
     1861 cgtgaaaaca ggaaggcaga gcgtctgatc aaacatgcac ggttcagact taatgctgag
     1921 ttatcaaagc tggattatcg taacaataga gggctggaca gggccctcat ccgttcactc
     1981 agtcagggaa actggttaac cctgaaacaa aatattttac tgaccggggc caccggcagc
     2041 ggtaaaacgt tcctggcatg tgcacttggt cataatgcct gccgacaggg atacaaggtc
     2101 tactattatc gccttaaagc gctgatggaa cagtgctatc aggggcatgc tgatggaaga
     2161 tacagcaaac ttttgaccag gctgaataat agcgatctgc tgcttctgga tgactggggg
     2221 ctggaacctc tctcatcaga acagcgtagc gacctgctgg aaatagtgga tctgatgtac
     2281 caacgaggct caatcatcgt agtgagccag ttgccggtgg aaaactggta caaaatgatc
     2341 ggagactcca cacatgcgga tgccatccta gatcgactgg ttcatggcag tatcaagatc
     2401 gaacttaaag gagaatcaat gcggaaaata caatctccgt tgaccgaagg agatcagtga
     2461 aggtaattta aaaacggttc tgtgaaagtg acacgaaccg atctccatcg atgttactca
     2521 ccgatctcct tcacggtaat acgcaacgta cgagttgtac gaaggtgacg ctgcctacaa
     2581 agctgcgctt gacaaagcat taaaaccggt cggactgagc ggcatgttcg gtaaaggcgg
     2641 gtatatggat ggccctggcg gaaacgtaac gccagtaacc attaacggta cagtctggct
     2701 ccagggcgac ggttgcaaag ccaatacctg cggctgggac tttatcgtaa cactctataa
     2761 cccaaaaacc catgaagtcg ttggctaccg ctactttggt ttagatgacc cggcctacct
     2821 ggtttggttc ggcgaaattg gcgtgcatga attcgcgtat ctggtgaaaa actacgtagc
     2881 tgcggttaac taatttaagg agtctgtcat gaaaactttt atcaaaactt tactcgttgc
     2941 tgtaactatt ctgttctctg tcttcgctgc ggcgaaacaa gtaaaactgc caaacaacat
     3001 caaatacgtt aatactacag aggcgttttc ctgtactgag attgacggta tgaattgcca
     3061 gacgaagaat ccgttcaact ataaagataa cagctatgtt ttcgtgcttg aacgtggtgg
     3121 tgcctggtgt tacgactaca ctgtctcggt acttaacctg aaaaccggga aagaacagat
     3181 gctcgaatac aaagacaacc agctgtgctc aggtagcaac aaaccgttct tcgaaatcaa
     3241 aaatggcgta ccgacggtag gagtcatcga cacatccgga aaacctgtcg ttgtggctct
     3301 ggacaaactt aaaacctgag gagtaaacca tgcgtttctc tgcacattat taatatcaaa
     3361 ggtaaataca gccccagcca ttgttgccgg aaagccgctt aatgcgtggc tcgccagtga
     3421 aaggcttctc agacaataaa cctcattcat ttcacccgtc aggccgcgtc ttctccggga
     3481 gacgtggctt ttttcattta ttacaccagt aaatcttaac caccgataag gagcaaatca
     3541 tgcgattaac cagtcgtttt ggttatgtaa accagatacg ccgtgaccgt ccgctgacac
     3601 acgaagaact gatgcaccat gtaccgggta ttttcggtga agaccggcat acctcctgca
     3661 gtgaacgcta tacgtacatc cccaccatca ccgtactgga aagcctgcag cgggaaggct
     3721 ttcatccatt cttcgcctgc cagacccgcg tacgtgaccc ggaccgccgg gaatacacca
     3781 aacacatgct gcgtctgcgc cgtaacggag agataaacgg agaacatgtc cctgaaatta
     3841 ttctgctcaa ctctcatgac ggtacctcca gctaccagat gctgccgggt tacttcaggt
     3901 tcgtctgcca gaacggatgc gtctgtggtc agtctctggg ggaagtgcgt gttccgcacc
     3961 ggggaaatgt ggtggacaga gtcattgaag gggcttacga ggtggtgggc gtgtttgacc
     4021 ggatagagga gaagcgtgat gccatgcagt cgctgattct gccgccaccg gcacgccagg
     4081 cgctggcaca ggcggcactg acttaccgtt atggtgacga acatcggccc gtcaccaccg
     4141 ccgacattct gacgccacga cgccgggagg attacggtaa ggacctgtgg agtacttatc
     4201 agaccatcca ggagaatatg ctgaaaggcg ggatttccgg tcgcagtgca aaaggaaaac
     4261 gtatccacac ccgtgccatt cacagcatcg acaccgatat taagctcaac cgcgcattgt
     4321 gggtaatggc agaaacgctg ctggagagcc tgcgctgatg cagcatgtcc ctgaaggcgt
     4381 gattcaggca ccagaatcac ccgacgcccc ggaggcgctg ccggggtgtc gttccatttc
     4441 tgatgatgac ctgtgcgcct ggtgtacccg tctgctttac cgtcccggag aaatcagtct
     4501 gtgcagactg agtacaggca atggcatctg gccatccgtc tgtgaccgga acggttacgc
     4561 gtacggctgt ccggaatttc agccgaatat cattcatccc tgatattacc gggtctcacg
     4621 gtcagtgatg aacgtgatgt tgccagctcc cgacctttac tccctctcat ttattcacat
     4681 tacaaggatt tcatacatga aaacattgtc tcagaacacc acctcttcgg cctgtgcacc
     4741 ggagactggc ctgcaacaac tggttgccac catagtccct gatgaacagc gcatcagctt
     4801 ctggccgcag cattttggcc tcattccaca gtgggtgacc ctggagcccc gtgtcttcgg
     4861 ctggatggac cgtctgtgcg aaaactactg cggtggtatc tggaatctgt acaccctgaa
     4921 caacggcggg gcatttatgg cccctgaacc ggatgactat gatgacgaaa catgggtact
     4981 gttcaatgcc atgaacggta accgcgctga aatgagcccg gaagccgccg gcattgccgc
     5041 ctgtctgatg acgtacagtc atcacgcctg ccgtacggag tgttatgcca tgacggttca
     5101 ttattaccgt ctgcgggatt acgccctgca gcatccggaa tgcagcgcca ttatgcgcat
     5161 tattgactga aagggggccg gaacaatgca acagatttcc tttctgcccg gagaaatgac
     5221 aaccagagag cgcagcctca ttcagcgggc cctgaaaacc ctggaccgcc atcttcatga
     5281 acccggcgtg gccttcacct ccacccgtgc ggcacgggaa tggctgattc tgaacatggc
     5341 gggactggag cgtgaagaat tccgggtgct gtatctgaat aaccagaatc agctgattgc
     5401 cggtgaaacc ctcttcaccg gcaccatcaa ccgcacggaa gtccatcccc gggaagtgat
     5461 taaacgcgcc ctgtatcaca atgccgcagc cgtggtgctg gcgcacaatc acccgtccgg
     5521 tgaagtcaca cccagtaagg cagaccggct tatcaccgaa cgtctggtac aggcactggg
     5581 cctggtggat atccgggtgc cggaccatct gatagtcggt ggcagccagg ttttctcctt
     5641 tgccgaacat ggtctgcttt aacccgtcac aaccacatca cacctgtttt cacttttatc
     5701 ttctgtcttc agaggtatcc cactatgaaa atcatcaccc gtggcgaagc catgcgtatt
     5761 caccgtcagc atcctgcatc ccgtcttttt ccgttctgta ccggcaaata ccgctggcac
     5821 ggcagtgctg aagcgtatac cggtcgtgaa gtgcaggata ttcccggtgt gctggccgtg
     5881 tttgctgaac gccgtaagga cagttttggc ccgtatgtcc ggctgatgag cgtcactctg
     5941 aactgagtca gtaagggcat tctgatgagc agaattatca ccaccaccgt gtatacactg
     6001 catgagctat cctccaccgc acaggaaaaa gcccgcgact ggtaccgtca gcatcatgct
     6061 gacagcaact ggtatgaaaa cgtgtatgag gacttcaggg cggtctgtgg cattttcgga
     6121 attgacctcc gccagcgcgt tttccggctc agcaacggca ggtttatgga agaggcgtgc
     6181 atctggttca gcggattctg cagccagggg gacggagcct gttttgaagg acgctggcac
     6241 tggcagccag caacagccag aaggctccgg gagtatgcca cacaggacca tgaactccat
     6301 cgtatcgcgg atgccctgca ggcggtgcag aaacgtaact tctggcaact gcaggctgaa
     6361 atccaccacc ggggacgtta ctgccatccg tacagcatgg atatcactgt tacccggaac
     6421 agtccgactg gtcaggctat gacagccgat gcggaagccg ctgtcagcga agccctgcgc
     6481 gacctggcct tctggttgta ccgtcagctg gaaaacgagt acgacaggct gacctctgat
     6541 gccgctgtgg atgaggccct tctcatcaac gaatacacct tcaccgaagc cggtctgcgc
     6601 gccggctgac ctgaggactt tatcgtgtca gacaaactcc atgagacaaa ttatcccgac
     6661 gaccataacg accgcctctg gtggggactg ccctgcaccg tgacgccctg tttcggggca
     6721 cgtctggtgc aggagggtaa ccggttgcat taccttgccg accgcgccgg tatcagaggc
     6781 ctgttcagcg atgcagatgc gtaccacctg gaccaggcct ttccgctgct gatgaaacaa
     6841 ctggaactca tgctcaccag cggtgaactg aatccccgcc atcagcatac cgtcacgctg
     6901 tatgcaaaag ggctgacctg caaagccgat accctcagca gttgtggtta cgtttatctg
     6961 gctgtttatc cgacgcccga aatgaaaaat taactctcca gaatagcctt ctgctacggc
     7021 ctggtgtttt caccacgcca cttttccatt tttatatctg catatcagga aaatcttcag
     7081 tatgaaaaca ttacctgtat tacccgggca ggcggccagt tctcgcccgt ctcctgttga
     7141 aatctggcag atactgctgt cccgactgct ggaccagcac tatggcctca cactgaatga
     7201 cacaccgttt gccgatgaac gtgtgattga gcagcatatt gaggcaggca tttcactgtg
     7261 tgatgcggtg aactttctcg tggaaaaata cgcgctggtg cgtaccgacc agccgggatt
     7321 cagcgcctgt acccgctctc agttaataaa cagcatcgat atcctccggg ctcgcagggc
     7381 gaccggcctg atgaccagcg acaattacag aacggtaaat aacattaccc tgggtaagta
     7441 tccggaggcg aaatgatgac actggaagcc gacagcgtta acgtacaggc gctggatatg
     7501 gggcacattg tcgttgacat tgatggtgtt aatatcactg aactgattaa taaggccgct
     7561 gaaaacggtt attcactccg cgtggtggat gaccgtgact ctaccgaaac accggcaact
     7621 tatgccagcc ctcaccagtt gctgtaagac aatgcagtga tacagggtat agtgccatta
     7681 accacagaaa cagcactgtt gtcctgtatt aagcaggcaa gagaagatgt ccttaccctg
     7741 cgccatctgc agcttctgca ccagaaccgg tgaatctcac tcaacaggct tcatttcccc
     7801 tgacgccagc ctgaatacag ctggcgtttt catttataaa cagaaaggaa aaccgataat
     7861 aatggaatgg acgccccgac catgaagcaa cggtaggata ttactgataa accttccagt
     7921 ggaggtgcgt tatggccgtt ttaacgatta gcattgacct gacaaaaaat gaattccaaa
     7981 tccacggtct gggtaggaac agaaaaatct aagctcagaa aacggattaa agtaagcgtc
     8041 aacggagcac cgtattgacg cttatttatt ggtgagaact acgttccatg gcaggagttc
     8101 gtcaacacgg ttggagggcc attccggcag tatgctcaga atatggcgca gatacgcttc
     8161 cggatcgata ccgttcagac ggcaggtgcc tgcttttccg gcaacaagca ggaatctcag
     8221 cgctgaagca ggaattagag gtaaaaacgc cctaccgggc catgaatcac ccggtcattg
     8281 gagtagtaac caaagcagat ttagccagca tggaacaaat atctttggtg acaagttggt
     8341 tacgggaagc tggagcgcac aacgtgttag taaccagtgc agttaataac aatggagtta
     8401 cagaactttt tgccttgctg catacagaag aaggctgttg ttaatttcga ttggttctca
     8461 gatgagaatg atgacggtga tacacagata agaatcaatg agcaatgagg gttgccgggc
     8521 aaccctcatt gaataaaacg ggaattactt cgcttcgccg tttttcattt cgcccatagc
     8581 tttcagcttt ttggagatat cgcggcgttc tttggagagc tcggcatttt tgatgatgta
     8641 atcgtcaacg cgatcttcat agtcaccttt catgctggcg atgatgccct ggattgcttc
     8701 aacgctcatc cctggcttga tgtaatcgct caggttgtcc agcaacagga cgcgcttctg
     8761 gttgtcacgg atctttttct caacgtcctg aatttcacgt tgcagtttgt tcttacgacg
     8821 gaacagacga acaaattcca gtacgtcctg gaatgaaggc ttggtagttt ccatttttat
     8881 acccctgata atgtgagagt cggattcgtt taagcaaccg ctattcgtta gggccaacat
     8941 tactcatagc tgccgcagat gacaatgctt ttatcccttt tcactatcat accctttatc
     9001 cttgctgaat cgaagcagca gcaagatgat tctgaagttc aggaattatt tgcgcaaggc
     9061 ccggcaaatc agattcgata gcaactcaag ctgatgtgcc gtttccatgt tcagccacac
     9121 ataaccatag attggtgttt ccaagacttt caggtcatgg tggttatcga gcaactgacg
     9181 cagctcttcc acagcatcgt tcaatttttc cgtattggca aaaaccggct gcggattacc
     9241 ttcgtacagc gcatgaacaa ggctcagcag tatttgctgc atcatgtgct gggtatcacg
     9301 aagtttttgc gcgttcaata acacgaaatg gctggggcgc gtggcccagt atgcattgat
     9361 ttgcaactcc agcatacaaa ccagattgcg attaatggtc tggatacctt catatatcga
     9421 tttgggaata cgggtttctt tgctggcggg cgcaatcagc ccacgcattt tcacggcatc
     9481 ggtcaggagt ttttgtagat ggctttccag acgtgggcgt tcgagtaagt tcggtgagaa
     9541 tgcagattga tagacccgat tatactcggt cagacttttc gccagttgaa tgcgccagtg
     9601 gatgaacgcc cgttgtggcc agataccggt aaacaacatt gccagtaaag agccgaggat
     9661 cacatcgccg cttcgccata acgccgtatc aatttcacct gtcggggaac ccacaacaat
     9721 tgccagcgtc accccaatca ataatccttg atacggtttc ttgcccagcg ccagccaacc
     9781 gcaaagaaac atcgccgccg cgcaccagac taacatcagc ggtaacgaaa ttaactccag
     9841 ttgcagagcg ataagaccta aaatcgaacc caacaccgta ccgccaatac gttcgaaggc
     9901 acgagggaca acgttccccc agaacgagat tggccccata atcaccacca tggtgaccag
     9961 cggccaggtg ctttccggga tagtaaacag gcggataatg agaaaagtga gcaggaatgc
    10021 cagcgcgacc cgagtaccat gcacaatgcg gtaatggcgg tatacccgga tttcaaacgg
    10081 gcttaatgac ttatcggcac gcacgcagaa actccgtaat gaagatgaaa agcgctcata
    10141 acacatctgt cggccagaag gcgcgcctct gagttatccg acggacatac cgggaacagt
    10201 gtaatttccc ggcaggagcg aaaaatttga aaggcgcatc ttactctttt cgctttcaaa
    10261 aaaagagtgg tcttcgcgtt aacacaccgc cctgagatga attagtgatg ttttggctgc
    10321 accgcaacat acatttcgat atcccagtac ccatcttccg cgccattgtt caagtaaacc
    10381 tcgaagcagg gctttggtaa catttcataa gcactgtcct gcaagaggct attaaagaac
    10441 tgataccagg gtttagcaaa atcatcaccg actacacgag ccaccgccac cgcatactga
    10501 ccacctgaaa tttctgtcag aatgacgccc tcactgtttt cggggagcgt aaagttattc
    10561 ggtaccgtca cgacggtgtc gcagcgtaat ttttcggcgg gtgtttcatc tggattgtcg
    10621 taatagacag caacccactc cttcggcaca atatttttgc tatctatcca catcatcaac
    10681 tgctcaaaac ctttctttac catctgctcc cacgggccaa caagatggaa acctgcaacg
    10741 gtacgtttat cttcctgctt aatctcgtag ttcatgacgc ctccactaac actgttttta
    10801 tatacagtat agttgcaata ttaaaaccac aaggaatgag tgttgattat gcgagcagac
    10861 tcgcactcct gccagtctgc tgcaaaagaa aggtcaggcc ttatggtgga aataatcact
    10921 caggcgggaa aacatgctgc cttccccgac agattccagg gtaaccagcg gccagtgcgc
    10981 cacctgttta tcacggtcgt aaagttcaat ttcccctacc cgctgatggg cgctaattgg
    11041 cgcggtgagt tctttaccat caagggtata tttggctttg atatgtggaa tttcggcttt
    11101 cggtagcacc atccagaact cttgttccgt tcccagggcg atattttctt tatcaccata
    11161 ccagatgcgt tccgtaccga cctttttccc acggtgcaaa atttgcaccg tagtaaagtt
    11221 ttgttgcccc caacgcagta attttcttgc ctcttcctca cgaccttttg cgctgtcagc
    11281 ccccattacc actgcaatga ggcgacgctg cccgtctaca gccgaagcaa taagattaaa
    11341 cccggcacca gaagtatggc ccgttttcag gccgtcaaca ttcatggttt tatcccacaa
    11401 taacccgtta cggttttgct gggtgatacc gttccaggtg aggcttttct cactgtacat
    11461 atgataaaac tcgggctcgc cgtggatgat agcgcgagaa agcacggcta aatcataagc
    11521 cgagctatgc tggccaggtg catccagacc atgcactgtt tcaaaatgcg tatccttgag
    11581 atgcagcttc tcggcatagt tgttcatcat ttcaacaaac tgccgttgcc caccggcaat
    11641 atagtcagcc agagcaacac aagcgtcatt tccggaatcc acaattaaac cacggcttaa
    11701 atcacgtacc gatacgcgat cgccctcttt caaaaacatc agtgaagaac cgacaaacac
    11761 cggattatct ttcgcccacg catcacgccc cacggtgaca atatcgtctg gcgtaatgcg
    11821 atgactatcg atagcgcgat ccacgacata gcccgtcatc agctttgtca ggctggcggg
    11881 attgcgctgt tgatgctcat tacccgcggt gagaatctga ccggtggtgt aatccatcaa
    11941 tacccaggac ccggcatgaa tctctggagg ctgaggtgaa aaaggaatgt tttccgccgc
    12001 aaaaccagac gataaattaa aaacgaacaa agaagcagca ataataagac ggcgtttcaa
    12061 cagcaaaccc tcaggtgttt caaatagctg ttctttttac ggaaatactt atgaactggc
    12121 tggaataaag tgcaagaaaa tgtgactact atctcatttt tatctgacat gatctgttgc
    12181 cactcgctgc caaattgtcg cgctaaagct gattagcacg gtgatatttg atactctggc
    12241 agacagcaga aataacggat ttaacctaat gatgaatgac ggtaagcaac aatctacctt
    12301 tttgtttcac gattacgaaa cctttggaac gcaccccgcg ttagatcgcc ctgcacagtt
    12361 cgcagccatt cgcactgata acgaattcaa tgtcatcggc gaacccgaag tcttttactg
    12421 caagcccgcg gatgactatt taccccagcc tggagcagta ttaattaccg gtattacccc
    12481 gcaggaggca cgggcgaaag gagaaaacga agccgcgttt gccgcccgta ttcactcgct
    12541 ttttaccgta ccgaagacct gtattctggg ctacaacaat gtgcgtttcg acgacgaagt
    12601 cacacgcaac gttttttatc gtaatttcta cgatccttac gcctggagct ggcagcatga
    12661 taactcgcgc tgggatttac tggatgttat gcgtgcctgt tatgccctgc gcccggaagg
    12721 aataaactgg cctgaaaatg atgacggtct accgagcttt cgccttgagc atttaaccaa
    12781 agcgaatggt attgaacata gcaacgccca cgatgcgatg gctgatgtgt acgccactat
    12841 tgcgatggcg aaactggtaa aaacgcgtca gccacgcctg tttgattatc tctttaccca
    12901 tcgtaataaa cacaaactga tggcgttgat tgatgttccg cagatgaaac ccctagttca
    12961 cgtttccgga atgtttgggg catggcgtgg caataccagc tgggtggcac cgctggcgtg
    13021 gcatcctgaa aatcgcaatg ccgtaatttt ggtggatttg gcaggagaca tttcgccatt
    13081 actggagctg gatagcgaca cattgcgcga gcgtttatat accgcaaaag ccgatcttgg
    13141 cgataacgcc gccgttccgg ttaagctggt gcatatcaat aaatgtccgg tactggccca
    13201 ggcgaatacg ctacgcccgg aagatgccga ccgactggga attaatcgtc agcattgcct
    13261 cgataaccta aaaattctgc gtgaaaatcc gcaagtgcgt gaaaaagtgg tggcgatatt
    13321 cgcggaagcc gaaccgttta caccttcaga taacgtggat gcacagcttt ataatggctt
    13381 tttcagtgac gccgatcgtg cagcaatgaa aattgtgctg gaaaccgagc cgcgtaattt
    13441 accggcactg gatatcactt ttgttgataa acgaattgaa aaactgttgt tcaattatcg
    13501 agcgcgcaac ttcccgggga cgctggatta tgccgagcag caacgctggc tggagcaccg
    13561 ccgccaggtc ttcacgccag agtttttgca gggctatgct gatgaattgc agatgctggc
    13621 acaacagtat gccgatgaca aagagaaagt ggcgctgtta aaagcgcttt ggcagtacgc
    13681 ggaagagatc gtctgaaaat aaatatcctc cggcatagcc ggaggttttt caaatgcgcc
    13741 tttaaggctc tcttaccagc cgcgccctaa caggcgcaca cgatctgaca tttgcatcca
    13801 acttcgttac ttacggcccg taaacgggct gcccggatag ggaatcgata actgctctcc
    13861 cattttatcc tcttcaagct ggtgctttat gtaatcctgt atcttcgccg tgttcttacc
    13921 caccgtatcg acgtaatacc ctctgcacca gaactccctg ttcctgtatt tgaatttcaa
    13981 atcaccaaac tgctcgtaag gcatcagact gcttttccct ttcagatatc ccataaagcc
    14041 tgatacgctc attttgggcg ggatctccac aagcatatgg atatgatctg cacagcattc
    14101 agcttccaga atccgtacac ttttccactc acacagcttt ctcaaaatac agcctattgc
    14161 tctacacttc tctctgtaga acacctgtct tcggtatttt ggcgcaaata ctatgtgata
    14221 tttacagttc catcgggtgt gcgctaagct cttttcgttc cccattggga cccccttttg
    14281 atttcttgtt tgacacttgc agttgccaga ccgcaaggtg ttttaacaaa tcaaaagggg
    14341 ttttaataac tggctcaaag ctgaaagctt tccggaaccc ccagcctagc tgggggtttt
    14401 ctgtgcacaa caaaaaagcc ggagcgacaa actccggctt tttgagattt accggatgat
    14461 tatgtcatcc ggtttgtaag attacgctac gtcttcgtac tgcggaaccg ggttacggaa
    14521 actcttggtt acgcaagcca ggtaaatcag accgatagca gcccagatca gacccagaac
    14581 cattgagctt tcttccaggt taacccacag cgcaccaacg gtcagcgcac cacacatcgg
    14641 caggaacaga tactggaagt gatctttcag cgttttgtta cgcttctcac ggatccagaa
    14701 ctgcgagatg accgacaggt taacgaaggt gaacgccacc aacgcaccaa agttaatcag
    14761 cgccgtagcc attaccaggt cgaagttgat tgccagcagg gcaatcgcgc caaccaggat
    14821 gatattcatc gccggagtac gccatttcgg gtgtacataa ccgaagaagc ttttcgggaa
    14881 cacgccgtca cgacccatta cgtacatcag acgcgcaacg cctgcgtgcg ccgccatacc
    14941 ggacgccagt acggtaatgg tggagaagat cagcgcgcca acctggaacg ctttacccgc
    15001 aacgtacagc atgatttcag gctgtgacgc atccggatct ttaaaacgag agatatccgg
    15061 gaagtacagc tgcaggaagt aagttgcaaa gatgaagatc atgccgccga tcagcgcggt
    15121 caggaaaatc gcacgcggga tcacgcgctc tgcatctttg gtttcttccg acaggttgct
    15181 gatgccgtca aaaccggtaa aggagaagca caggattgtc gccccggtaa tcatcgggat
    15241 aacatgcgca tcgccagacc agaacggacg agtgctcgcc agcgtaccag cgccttcacc
    15301 ttcaaatacg ccataaacaa ccatgcccag aatcaccgcg atcagcacta tctgcaacac
    15361 gacgattaca gtgttgaagt tcgctacgga tttcagacta cgcaggttaa aggcggtcat
    15421 aaaggccacc agagccacca caaacatcca cgatggaatg gaaggcacca gagcttcaaa
    15481 atagattttc gccagcagaa tgttgatcat cggcgcgaac agatagtcga gcagagaaga
    15541 ccaacccacc ataaagccga cagtcgggct aatggatttc tgggcgtaag tgtatgcaga
    15601 gccagcagaa ggatagcggc gaaccagctt cccgtagctc agagccgtaa acaggatcgc
    15661 aatcaatgcg aacgcatagg ctgtcggcac atgaccatcc gtgaggcctg aaacgatacc
    15721 aaatgtatca aacagcgtca tcggctgcat ataggctaga cccatcatta caaccggaac
    15781 taacgtaagc gttttacgca attccacgcg agaggtgttt ggagtaacgt tatgcgacat
    15841 ggtcattctc ctttacggtg ataaccgtcg cgtaagcaaa aaattgcccc atttttttgg
    15901 attcctcagc gacaacaact gtcgattttt agtaaatatc tatccggtac gaagcccggc
    15961 ctcttggtat gaatgattgg tttgaagcaa aaaataaccg acgctaatta aacgtcggtt
    16021 tttagtcatt ttttgacagc ggcgcattgt gcctaaatgg gggggaaatg acaagagaat
    16081 gagaggcttg ccataataat ttttctttaa atggctgatt ttccgtcatc agattttgca
    16141 taaacaccgg cgatcgcact atttgctaaa atttcatctc gccaccagcc gctggcaagc
    16201 cctgcggtct gttcattcca gccaatccag acgggttcaa agagagtttg ggcgaccact
    16261 ttcttctcga ttaacgcgcc actatcgaga aaacgttgcg ccagataccg tggtaaatag
    16321 ccgcagccaa ggccgctaat ttgcagctcc agcttggttt taaaatcgaa aacggtaatg
    16381 gcttcttgtt cgtcgagaag ttgtgaggcc gtagaagcgc ctgcctgcgc agtgtccccc
    16441 accacaatcg cccgatatcg tttaatgata cgacggttta acggttcttc ttcctgggct
    16501 aacggatgat gaggcgcgac cgcaaagact tgttcaagat cgcccaaccg cgagaaacca
    16561 aactcactgg aagatggtgg ctcatgcatc gcgccaacga taatatccgc tcgcccctga
    16621 gtcagggcat cccaggaacc accgagtacg ccattgataa acttcaggcg cgtcacgcta
    16681 tgatgttgat aaaaagcttc aatgagaggc gcaagcagag aaaaaggaaa cgtgtcgtcc
    16741 acgccaatca ccagctcgtt ttcccagcct tcatgcagtt tgatcgcctg cttttccagt
    16801 tctcgcacgg tatgcagaac ttcccgccct ttctctaata acatttttcc ggtacgggtg
    16861 aatttagcgc ggtgtccgct acgatcaagc aattgaatat taaggtcgct ttccagcttg
    16921 tgaacggtgt aactcagagc ggacggcgtc ttgtagagtt tggctgacgc cgccgcaaaa
    16981 ctgccttctt tttctaaggc atcgaggatc atcaacacat ccagcagtgg tttcatacac
    17041 gcccccttgc agtgcatgcg gcgtcctgct ggcgtgatcg tttactccag cggcattacc
    17101 agcggatcgg gatactggta ttcaaatccc agttcattac aaatccgact gccatcaata
    17161 atcttacctt tgccgctgtc cagactattt ctgaactgcg gaggttccag ccccagtaaa
    17221 cgggccatct gcggatagaa aacattacgc gcagggtgag ctggcgcaca tatattatag
    17281 atgtgtccgc ctttaggtgc ctgtaacaac agagtgatag cgccaataac atcttctaaa
    17341 tggactaaat taacaccatg ttcaccatca ggggcggttt ttccggcaaa gaagcgtccg
    17401 ggatgacgtc ccggtccgac caggcccgca agacgcagaa tatcgaccga agtaccgggt
    17461 aaattgtgca gccagtcttc gagttcttct aatactcgtc cactgttggt taccggatta
    17521 cgcggggtgg tttctttcac cgtgccttgt gcgtcgccat agacagacgt cgagctggta
    17581 aaaataatac ggggaatacg atgagccagc gcgctatcca ctaactcttg taccgcttgt
    17641 aaatagaact catcgccggg gccgctacga cgtgccggaa gcgtaatgac cagcgcatcg
    17701 gcatccataa gggcatccag atcgtcagaa tcgcaaacta actcaggctc catgcgaagc
    17761 agatagctat caatgccact cattcgggcc gcttcgacac catcttgtgt ggttttactc
    17821 ccggtgactt gccagcctcg cgctgaaagt gacatcgcca gcggcatacc taaccaccct
    17881 aacccgacaa ttgcgacctt tttcatccgt tatctcctga tacaccttag atctataagg
    17941 ctacgctagc gtatcaaaac tgacaattca ttctatgaat gaatctcttc aataatgata
    18001 acgacatgct gcaatgagca gtgaatcatc agtaaccgcg tataccagaa ggtgctcctc
    18061 tgtaatgcgt cgggaccaga aacctgacaa gttatgtttc aggggttctg gtttcccctt
    18121 accttcaaat ggtgttctgc gggtatcttt gataagttca ttgatctttt taacaattcg
    18181 cttatctgct tcctgccagt acagataatc atcccatgat tcctcagacc agattagttt
    18241 cactcaataa tgtccttttc cgttcctttg tctgatttca ggctatcgat tgagtccatc
    18301 aatctccggg cgttagcggg ggaacgcagt agataagccg tctcttccag cgagttgtat
    18361 tcttcgagtg acatcagaac acaagcctct ccattctgac gagtaatgag gatcggggca
    18421 tgatcttcaa cggctttcat cattgttgcc gacaaattct gacgcgcttc gctgtagcta
    18481 attgtacgca tgtaaatctc ctcttttgta cagttcattg tacaatgatg ggtgttaatt
    18541 aactatttat taattagttt gtagatcaag acattgccag cgagacgaaa aatcagactt
    18601 tgctcttttt ggtgctgtca agttagagga cagtcctctt agcccccttc tttccccgct
    18661 cattcattaa acaaatctat cgccataaaa tatataaaaa agcccttgct ttctaacgtg
    18721 aaagtggttt aggttaaaag acatcagttg aataaacatt cacagagact tttatgacac
    18781 gcgttcaatt taaacaccac catcatcacc atcatcctga ctagtctttc aggcgatgtg
    18841 tgctggaaga cattcagatc ttccagtggc gcatgaacgc atgagaaagc ccccggaaga
    18901 tcaccttccg ggggcttttt tattgcacga ttgataacgg ttcagacagg tttaaagagg
    18961 aataagaaaa tgacagacaa cactcgttta cgcatagcta tgcagaaatc cggccgttta
    19021 agtgatgact cacgcgaatt actggcgcgc tgtggcatta aaatcaatct tcacacccag
    19081 cgtctgatcg cgatggcaga aaacatgccg attgatattc tgcgcgtgcg tgacgacgat
    19141 attcccggtc tggtaatgga cggcgtggta gaccttggga ttattggcga aaacgtgctg
    19201 gaagaagagc tgcttaaccg ccgcgcccag ggtgaagatc cgcgctactt taccctgcgt
    19261 cgtctggatt tcggcggctg ccgcctttcg ctggcaacgc cggttgatga agcctgggac
    19321 ggtccgctct ccttaaacgg taaacgtatc gccacctctt atcctcacct gctcaagcgt
    19381 tatctcgacc agaaaggtat ctcttttaaa tcctgcttac tgaacggttc tgtcgaagtt
    19441 gcgccgcgtg ccgggctggc ggatgcgatt tgcgatctgg tttccaccgg tgccacgctg
    19501 gaagctaacg gcctgcgcga agtcgaagtt atctaccgct cgaaagcctg cctgatccag
    19561 cgcgatggcg aaatggaaga atccaaacag caactgatcg acaaactgct gacccgtatt
    19621 cagggtgtga tccaggcgcg cgaatcaaaa tacatcatga tgcacgcacc gaccgaacgc
    19681 ctggatgaag tcatcgccct gctgccaggt gccgaacgcc caaccattct gccgctggcg
    19741 ggtgaccaac agcgcgtagc gatgcacatg gtgagtagcg aaaccctgtt ctgggaaacg
    19801 atggaaaaac tgaaagcgct gggtgccagt tcaatcctgg tcctgccgat tgagaagatg
    19861 atggagtgat cgccatgagc tttaacacaa tcattgactg gaatagctgt actgcggagc
    19921 aacaacgcca gctgttaatg cgcccggcga tctccgcttc tgaaagcatt acccgcaccg
    19981 ttaacgatat tctcgataac gtgaaaacgc gtggcgatga ggccctgcgt gaatacagcg
    20041 cgaagtttga taaaaccacg gttaccgcgc tgaaggtgtc tgctgatgag atcgccgccg
    20101 ccagcgaacg cctgagcgac gagctaaaac aggcgatggc ggtggcagta aagaatattg
    20161 aaaccttcca cactgcgcaa aaactgccgc cggtagatgt agaaacgcag ccaggcgtgc
    20221 gttgccagca ggtcacgcgc ccggtggctt cagtgggttt gtatattcct ggcggctccg
    20281 ccccgctctt ctcaacggta ttaatgctgg cgactccggc gcgtattgcg ggctgtaaaa
    20341 aagtggtgct gtgctcaccg ccgccgattg ccgatgagat cctttatgcg gcgcaactgt
    20401 gcggtgtgca ggacgtgttt aacgtcggcg gcgcacaggc cattgccgcg ctggcgtttg
    20461 gtacggaatc tgtgccgaaa gtggacaaaa tcttcgggcc gggtaacgcc tttgtcaccg
    20521 aagcaaaacg ccaggtaagc cagcgtctgg acggtgcggc gatcgatatg cccgcaggcc
    20581 cgtcggaagt gctggtgatt gctgacagcg gcgcaacgcc ggatttcgtg gcttctgatt
    20641 tgctctccca ggctgaacac ggcccggact cacaggtgat tttactgaca cctgatgctg
    20701 atatggcgcg tcgcgttgcc gaggccgtcg aacgccagtt ggcagaattg ccgagagctg
    20761 aaaccgcccg tcaggcactg agcgccagcc gcctgatcgt aaccaacgat ttagcgcagt
    20821 gcgtagagat ctccaatcag tacggtccgg agcacctgat cattcagacc cgcaacgccc
    20881 gcgatctcgt cgatagcatt accagcgccg gttcggtatt tctcggtgac tggtcaccgg
    20941 aatcggcagg tgattacgcc tccggcacca accacgtgct gccgacttac ggttacaccg
    21001 ccacctgttc cagcctcggg ctggcagatt tccagaaacg catgaccgta caggaactgt
    21061 cgaaagaagg tttctccgcg ctggcttcga ccattgaaac actggccgcc gccgagcgcc
    21121 tgaccgccca caaaaatgcc gttactttgc gtgttaacgt ccttaaggag caagcatgag
    21181 caccgtgact attactgatt tagcgcgtga aaacgtccgc aacctgacgc cgtatcagtc
    21241 ggcgcgtcgt ctgggcggta acggcgacgt ctggctgaac gccaacgaat atcccacagc
    21301 cgtggagttt cagcttactc agcaaacgct caaccgctac ccggaatgcc agccaaaagc
    21361 ggtgattgaa aattacgcgc aatatgcagg cgtaaaaccg gaacaggtgc tggtcagccg
    21421 tggcgcggac gaaggtattg aactgctgat ccgcgctttt tgcgaaccgg gtaaagacgc
    21481 catcctctac tgcccgccaa cgtacggcat gtacagcgtc agcgctgaaa ccattggcgt
    21541 cgaatgccgc acagtgccga cgctggaaaa ctggcaactg gacttacagg gcatttccga
    21601 caagctggac ggcgtaaaag tggtctatgt ttgcagcccc aacaacccca ccgggcaact
    21661 gatcaaccca caggattttc gcaccctgct ggagttaacc cgcggtaagg cgattgtggt
    21721 tgccgatgaa gcctatatcg agttttgccc gcaggcatcg ctggctggct ggctggcgga
    21781 atatccgcac ctggctattt tgcgcacact gtcgaaagct tttgctctgg cggggcttcg
    21841 ttgcggattt acgctggcaa acgaagaagt catcaacctg ctgatgaaag tgatcgcccc
    21901 ctacccgctc tcgacgccag ttgccgacat tgccgcacag gcgttaagcc cgcagggaat
    21961 cgtcgccatg cgcgaacggg tggcgcaaat tattgcagaa cgcgaatacc tgattgccgc
    22021 actgaaagag atcccctgcg tggagcaggt tttcgactct gaaaccaact acattctggc
    22081 gcgctttaaa gcctccagtg cagtgtttaa atctttgtgg gatcagggca ttatcttacg
    22141 tgatcagaat aaacaaccct ctttaagcgg ctgcctgcga attaccgtcg gaacccgtga
    22201 agaaagccag cgcgtcattg acgccttacg tgcggagcaa gtttgatgag tcagaagtat
    22261 ctttttatcg atcgcgatgg aaccctgatt agcgaaccgc cgagtgattt tcaggtggac
    22321 cgttttgaca aactcgcctt tgaacctggc gtgatcccgg agctgctgaa gctgcaaaaa
    22381 gcgggctata agctggtgat gatcaccaat caggatggtc tgggagcaca aagtttcccg
    22441 caggcggatt tcgatggccc gcacaacctg atgatgcaga tcttcacctc gcaaggcgtg
    22501 cagtttgatg aagtgctgat ttgcccacac ctgcccgccg atgagtgcga ctgccgtaag
    22561 ccgaaagtaa aactggtgga gcgttatctg gctgagcaag cgatggatcg cgctaacagt
    22621 tatgtgattg gcgatcgcgc gaccgacatt caactggcgg aaaacatggg cattaatggt
    22681 ttacgctacg accgcgaagc cctgaactgg ccaatgattg gcgagcaact cactaaacga
    22741 gaccgttacg cccatgtagt gcgcaacacc aaagagacgc aaattgacgt ccaggtgtgg
    22801 ctggatcgcg agggtggcag caagattaac accggcgttg gcttctttga tcacatgctg
    22861 gatcagatcg ccacccacgg cggtttccgt atggaaatca acgttaaagg cgacctctat
    22921 atcgacgatc atcacaccgt cgaagatacc ggcctggcgc tgggggaagc attaaaaatt
    22981 gctcttggcg acaaacgcgg tatttgccgg tttggttttg tgctgccgat ggacgaatgc
    23041 cttgcccgct gcgcactgga tatctctggt cgcccgcacc tggaatataa agccgagttt
    23101 acctaccagc gtgtgggcga tctcagcacc gagatgatcg agcacttctt ccgttcgctc
    23161 tcatacacca tgggcgtgac gctacacctg aaaaccaaag gtaaaaacga tcaccaccgt
    23221 gtagagagcc tgttcaaagc gtttggccgc accctgcgcc aggccatccg cgtggaaggc
    23281 gacaccctgc cctcgtcgaa aggagtgctg taatgaacgt ggtgatcctt gatactggct
    23341 gcgccaacct gaactcggtg aagtctgcca ttgcgcgtca cggttatgaa cccaaagtca
    23401 gccgtgaccc ggacgtcgtg ttgctggccg ataaactgtt tttacccggc gttggcaccg
    23461 cacaagcggc gatggaccag gtgcgcgagc gcgagctgtt tgatctcatc aaagcctgta
    23521 cccaaccggt gctgggcatc tgcttaggga tgcaactgct ggggcggcgc agcgaagaga
    23581 gcaacggcgt cgacttgctg ggcatcatcg aagaagacgt gccgaaaatg accgactttg
    23641 gtctgccact gccacatatg ggctggaacc gcgtttaccc gcaggcaggc aaccgcctgt
    23701 ttcaggggat tgaagacggc gcgtactttt actttgttca cagctacgca atgccagtca
    23761 atccgtggac catcgcccag tgtaattacg gcgaaccgtt caccgcggcg gtacaaaaag
    23821 ataacttcta cggcgtgcag ttccacccgg agcgttctgg taccgctggc gctaagttgc
    23881 tgaaaaactt cctggagatg tgatgattat tccggcatta gatttaatcg acggcaccgt
    23941 ggtgcgtctc catcagggcg attatggcaa acagcgcgat tacggtaacg acccgctgcc
    24001 gcgcttacag gattacgccg cacaaggtgc cgaagtactg cacctggtgg atctgaccgg
    24061 ggcaaaagat ccggctaaac gtcaaatccc gctgattaaa accctggtca cgggcgttaa
    24121 cgtcccggtg caggttggcg gcggcgtgcg tagcgaagaa gacgtggcgg cgttactgga
    24181 agcaggcgtt gcgcgtgtgg tggttggctc caccgcggtg aaatcaccag aaatggtgaa
    24241 gggctggttt gaacgttttg gtgccgatgc cttagtgctg gcgctggatg tccgtatcga
    24301 cgagcaaggc aacaagcagg tggcagtcag cggctggcaa gagaactcgg gcgtttcact
    24361 ggaacaactg gtggaaacct atctgcccgt cggcctgaaa catgtgctgt gtaccgatat
    24421 ctcgcgcgac ggcacgctgg cgggatctaa cgtcttttta tatgaagaag tgtgtgccag
    24481 atatccgcaa gtggcgtttc agtcctccgg cggcattggc gatattaacg atgtggcggc
    24541 cctgcgtggt actggtgtgc gcggcgtaat agttggtcgt gcattactgg aaggtaaatt
    24601 caccgtgaag gaggccatcg catgctggca aaacgcataa tcccgtgtct cgacgttcgt
    24661 gatggtcagg tggtgaaagg cgtacagttt cgcaaccatg aaatcattgg cgatatcgtg
    24721 ccactggcaa aacgctacgc cgaagaaggt gcagatgaac tggtgttcta cgatatcacc
    24781 gcttccagcg atggccgtgt ggtagataaa agctgggtat ctcgcgtggc ggaagtaatc
    24841 gacattccgt tttgtgtggc gggtgggatt aagtctctgg aagatgccgc gaaaattctt
    24901 tcctttggcg cagataaaat ctccatcaac tctcctgcgc tggcggaccc gacgttaatt
    24961 actcgcctgg ccgatcgctt tggcgtgcag tgtattgtgg tcggtattga tacctggtac
    25021 gacgccgaaa ccggtaaata tcatgtgaat caatataccg gcgatgaaag ccgcacccgc
    25081 gttactcagt gggaaacgct cgactgggta caggaagtgc aaaaacgcgg tgccggagaa
    25141 atcgtcctca acatgatgaa tcaggacggc gtgcgtaacg gttacgacct cgagcagctg
    25201 aaaaaagtgc gtgaagtttg ccacgtcccg ctgattgcct ccggtggcgc gggcaccatg
    25261 gaacactttc tcgaagcctt ccgcgatgcc gacgttgacg gcgcgctggc agcttccgta
    25321 ttccacaaac aaataatcaa tattggtgaa ttaaaagcgt acctggcaac acagggcgtg
    25381 gagatcagga tatgttaaca gaacaacaac gtcgcgaact ggactgggaa aaaaccgacg
    25441 gtctgatgcc ggtgattgtg caacacgcgg tatccggcga agtgctaatg ctgggctata
    25501 tgaacccgga agccttagac aaaaccctcg aaagcggcaa agtcaccttc ttctcgcgca
    25561 ctaaacagcg actgtggacc aaaggcgaaa cgtcgggcaa tattctcaat gtggtgagta
    25621 ttgccccgga ctgcgacaac gacacgttac tggtgctggc aaatcccatc ggcccgacct
    25681 gccacaaagg caccagcagc tgcttcggcg acaccgctca ccagtggctg ttcctttatc
    25741 aactggaaca actgctcgcc gaacgtaaat ctgccgaccc ggaaacctcc tacaccgcca
    25801 aactgtatgc cagcggcact aaacgcattg cgcagaaagt gggcgaagaa ggcgtggaaa
    25861 ccgcactggc agcaacggta catgaccgct ttgagctgac caacgaggca tctgacttga
    25921 tgtatcacct gctggtgttg ttgcaggatc aggatctgga tttagcgacg gtaattgaga
    25981 acctgcgtaa acggcatcag tgagttgcgt gctgaccgga tgcgatgttg ttgtcgcatc
    26041 cggagccatt gcccgatgcg caagcttatc gtgcctacac attatctcaa cacacgtagg
    26101 ccggataaga tgcgccagca tcgcatccgg caaaaaaaac gggcatggtg tcaccaccct
    26161 gcccgtttct cttaaatgca caataatatt atttcgcgtt gtaattacgc agcgcgttac
    26221 gccccaacac aatccccacg ccaaccatgc cgcccagcag caccgccaga atcaaggtaa
    26281 ttgccttttt cgggctatcg cgacgaatag gtaacgtcgg tttcattaca tagcggtaag
    26341 catgaatatc aagtttatca acgtcaagat tgtcgatatc cagcaggttt tgacgagtct
    26401 gatagtagct tgatgagaac accaacggac gggtcgcctc gtgcttaatc atcgactcca
    26461 gcgcttcgct ccccaaaagg aacatagtat cctgggttac gtcctgcgtc tgttgaatct
    26521 gcggctttgt cacctgcgcc tgattcgcat actgcaacgc ttcctgaatc tgacggatac
    26581 gcagatcttt ctgttcctgc gcgaccactt cctgggttct taaagagtcc tgcaagtttt
    26641 tccgtcccag agcaatgttg tccttgagat ccttttctag ctcttgattc actttatcat
    26701 caacttgctg aatgtattgg gccaacttca tttgtgcgcc ctctgcagtt tgcccaacat
    26761 aagaaacagt caatggtaat tgctggttct taacagaagg ttcgatggta agtttttctg
    26821 gctcttcctg attatccagc gtttctgcta atgcagagaa ggcagaactg aagcgaccaa
    26881 ttaacgtctc ctgcaaatcc gatactttcg gtgtagcctg accatagata acattcatgg
    26941 cattgttata gccagcaatt tgccccacgt cgggctgagt gataattgct gttgacgtcc
    27001 atttctcctt cgctactgcc aaataaccaa tagccagggc aatagccaca atgacggaaa
    27061 tgatgattgt catcttgcca cgccacaact gcactagtaa atcaatcaaa tcaatctgtt
    27121 ccgggtcatg gttttgccca gaaacattat tattttctac tctcatcatt accctaactg
    27181 acggaaattt ccaagtccgc atagtttagc gataatcctc gtgaatgcta taggataagt
    27241 gataaaaata atgaattgtt gaggaagtaa caaaagacaa tcagggcgta aatagccctg
    27301 ataacaagat gttaatcgct accaaagaga tcgcgggtgt ataccttatc tgccacatcc
    27361 ttaagctctt ctgccatacg attggagata atgacatcag cttgttgttt gaaagtggcg
    27421 agatctcgtt ccaggcgaga gttgaagaat gagtcttctt tcatcaccgg ttcgtaaatg
    27481 atcacttcaa cgcctttcgc cttgatacgt ttcataatcc cctgaatgga agacgcgcgg
    27541 aagttgtctg aaccgctctt cataatcaga cgataaatac ccaccacttg cggcttgcgt
    27601 gacaaaatgg catcggcaat aaaatcttta cgcgtgcggt tagcatcgac aattgccgaa
    27661 atcaggttat tcggcacaga ctgataattc gccaataact gtttggtatc tttcggcaaa
    27721 caataaccac cataaccaaa cgacggattg ttgtaatggt tgccgatacg cgggtcgaga
    27781 caaacacctt cgataatctg acgcgtattc agacccaaac tttctgcata gctatccagt
    27841 tcgttaaagt acgccacgcg catcgccaga taggtattag cgaaaagttt aatcgcttct
    27901 gcttcagtgg agtcggtaaa cagggtcggg atattttgct taatcgtgcc ttcctgtaac
    27961 aacgcagcaa aacgttctgc gcgttctgaa cgctcaccga tgacaatacg tgacggatga
    28021 aggttatcgt aaagggcttt accctcacgg agaaattccg gggagaatat aatattttca
    28081 gtacgatatt ttttatgcat cgctgcggta aaaccaacgg gaaccgttga tttgatgacc
    28141 ataaccgcat aagggtttat ctcaactacg tctttaatta ctgattctac actggatgta
    28201 ttgaaataat tagttttagg atcatagtcg gttggagtgg cgatgatgac ataatcagca
    28261 tcccggtagg cttcattttt atctaatgtg gcattaaagt gtattttatc tgattgcaaa
    28321 aactgctgaa tttccttatc aacaatagga gatatccgat cattcagcat agcaacgcgt
    28381 gacggtaaaa tatctaatgc cacaacctca tgattttgtg cgattagaag cccgtttgac
    28441 aagcctacat agccagtacc ggaaatggta attttcattt catgctctca gaattaactt
    28501 aactgtgaat catgatgttt ttagcatcct gacaagagtt aaaagtttta acgctacgtc
    28561 gatagctggt caacgcaacg aaaaacaatt cagaatttct ttataagaat agctgatatt
    28621 tattaagtta atattaagca gtgaaattta gtctataaga taaatggcaa aaaaagcccg
    28681 gcacaatata cgccgggcct caatttattg ttagttaagt cagattaatc cagccattcg
    28741 gtatggaaca caccttcttt atcgatgcgc ttataagtat gtgcaccgaa atagtcacgc
    28801 tgtgcctgga tcaggtttgc aggcagaaca gcggcacggt agctgtcata ataggcaacc
    28861 gcagcggcga aggtcggaac cgggataccg ttctgtactg cataagcaac gacatcgcgc
    28921 agcgcctgct gatagtcatc ggcgatttgc ttaaagtacg gagccagcag caggttagcg
    28981 atctgcggat tttcggcgta tgcatcggtg attttctgca ggaactgcgc acggatgatg
    29041 cagccagcac ggaaaatctt cgcgatttcg ccgtagttca gatcccagtt gtattcttca
    29101 gacgcagcac gcaactgaga gaagccctga gcgtaagaaa cgattttgcc cagatacagc
    29161 gcacgacgaa ccttctcgat aaactcagct ttgtcgcctg ctcgctgcgc ttgcgggcca
    29221 gagagaactt tagacgcggc aacgcgctga tctttcagag aagagatata acgtgcaaac
    29281 acagactcgg taatcagcga cagcggttcg ccgagatcca gcgcgctctg gctggtccat
    29341 ttacccgtac ctttgtttgc agcttcatcc agaatcacat caaccaggta gttaccgtct
    29401 tcatcttttt tggtgaagat atctttggta atgtcaatca ggtagctgct cagttcaccg
    29461 ttattccact cggtaaaggt ctgcgccagt tcttcgttgg tgaggttcag gccaccttta
    29521 agcagagaat aggcttcagc aatcagctgc atatcaccgt attcaatacc gttgtgaacc
    29581 atcttcacat agtggcctgc gccatcggca ccaatatagg taacgcatgg ctccccgtct
    29641 tcagccactg cggcgatttt ggtcaggatc ggcgcaacca gttcataggc ttctttctgg
    29701 ccaccaggca taatggaagg tcctttcagc gcgccttctt caccgccaga aacaccagta
    29761 ccgatgaagt taaagccttc tgcagaaagc tcacgattac gacgaatagt gtcctggaag
    29821 aaggtgttac caccatcaat gatgatgtca cctttatcga ggtacggctt aagggaatca
    29881 atagcagcat ccgtgcctgc acctgctttc accattaaca ggatgcgacg aggcgtttcc
    29941 agagattcaa caaactcttt caccgtatag taaggaacca gttttttgcc tggattttcg
    30001 gcaatcactt cttccgtttt ttcacgggaa cggttgaaaa tagagacggt ataaccacgg
    30061 ctttcgatgt tgagcgcaag gttgcgcccc atcactgcca taccgacgac gccgatctgt
    30121 tgctttgaca ttgtttactc ctgtcagggc gttaaaaaat tggtatataa agcaaagatc
    30181 tttaaataaa gataccattt cagtagtaaa attaggactt tatttaatca ctttaccagt
    30241 tcggatgtaa tttttctata gtttttataa gaaagaattg gtttccgtaa tatgtagcgc
    30301 gtaatactcc ttatatgcca tcgaaatgct ttagtaaata ttcttctatt ttcatgctgc
    30361 gcataatgaa tagcatcaaa atggggagta tagtaaagat ctactccact taattttaaa
    30421 cgcatacaaa ggtcaatatc ttcacaatac ataaaatatt tttgatcaaa accattcaca
    30481 tttaagaaac ttaaagcatg aataagcata aatga
//
LOCUS       DAFGPF010000055        30460 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFGPF010000055 DAFGPF010000000
VERSION     DAFGPF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30460
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.055"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1005
                     /locus_tag="LSX49_002731"
     CDS             <1..1005
                     /locus_tag="LSX49_002731"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBL7169124.1"
                     /translation="GGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVE
                     LREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADT
                     GIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDE
                     EALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVA
                     AYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPA
                     FTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT
                     "
     gene            1161..2696
                     /gene="gadC"
                     /locus_tag="LSX49_002732"
     CDS             1161..2696
                     /gene="gadC"
                     /locus_tag="LSX49_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HBL7169125.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDAKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKSKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
     gene            2827..4146
                     /locus_tag="LSX49_002733"
     CDS             2827..4146
                     /locus_tag="LSX49_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HBL7169126.1"
                     /translation="MDICSRNEKLAIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPVSSVNNSNPTSRARVQQQAMIDKLDHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPGSRLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPEVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
     gene            4524..4687
                     /locus_tag="LSX49_002734"
                     /pseudo
     CDS             4524..4687
                     /locus_tag="LSX49_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            4712..7111
                     /gene="dosP"
                     /locus_tag="LSX49_002735"
                     /gene_synonym="pdeO"
     CDS             4712..7111
                     /gene="dosP"
                     /locus_tag="LSX49_002735"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase"
                     /protein_id="HBL7169127.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPQYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCINEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEVQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGASFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNRDYL
                     LSTAHNAMDFIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWYDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGIGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            complement(7301..7732)
                     /gene="osmC"
                     /locus_tag="LSX49_002736"
     CDS             complement(7301..7732)
                     /gene="osmC"
                     /locus_tag="LSX49_002736"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HBL7169128.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
     gene            8075..8290
                     /gene="bdm"
                     /locus_tag="LSX49_002737"
     CDS             8075..8290
                     /gene="bdm"
                     /locus_tag="LSX49_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310112.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HBL7169129.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAEHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            8392..8529
                     /gene="sra"
                     /locus_tag="LSX49_002738"
     CDS             8392..8529
                     /gene="sra"
                     /locus_tag="LSX49_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HBL7169130.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            8685..10382
                     /gene="maeA"
                     /locus_tag="LSX49_002739"
     CDS             8685..10382
                     /gene="maeA"
                     /locus_tag="LSX49_002739"
                     /EC_number="1.1.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HBL7169131.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLV
                     LPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWHAEYRDYRRTSI"
     gene            10516..11526
                     /gene="adhP"
                     /locus_tag="LSX49_002740"
     CDS             10516..11526
                     /gene="adhP"
                     /locus_tag="LSX49_002740"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HBL7169132.1"
                     /translation="MKAAVVTKDHHVDVTDKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATKMGADLAINSRTEDA
                     AKIVQEKAGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLEDINTIFTEMEEGKIRGRMVIDF
                     RR"
     gene            11712..11989
                     /locus_tag="LSX49_002741"
                     /pseudo
     CDS             11712..11989
                     /locus_tag="LSX49_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011039853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            11989..12273
                     /locus_tag="LSX49_002742"
     CDS             11989..12273
                     /locus_tag="LSX49_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HBL7169133.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
     gene            complement(12323..12976)
                     /gene="fdnI"
                     /locus_tag="LSX49_002743"
     CDS             complement(12323..12976)
                     /gene="fdnI"
                     /locus_tag="LSX49_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HBL7169134.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPIQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI"
     gene            complement(12969..13853)
                     /gene="fdnH"
                     /locus_tag="LSX49_002744"
     CDS             complement(12969..13853)
                     /gene="fdnH"
                     /locus_tag="LSX49_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase N subunit beta"
                     /protein_id="HBL7169135.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDEEEGNHE"
     gene            complement(13866..16913)
                     /gene="fdnG"
                     /locus_tag="LSX49_002745"
     CDS             complement(13866..16913)
                     /gene="fdnG"
                     /locus_tag="LSX49_002745"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(16326..16328),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HBL7169136.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDDTLTHPRCVWNLLKAHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQAEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGIANGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            17145..18026
                     /gene="yddG"
                     /locus_tag="LSX49_002746"
     CDS             17145..18026
                     /gene="yddG"
                     /locus_tag="LSX49_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HBL7169137.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAVYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
     gene            18299..19687
                     /gene="narU"
                     /locus_tag="LSX49_002747"
     CDS             18299..19687
                     /gene="narU"
                     /locus_tag="LSX49_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter NarU"
                     /protein_id="HBL7169138.1"
                     /translation="MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLL
                     LAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRW
                     TVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK
                     QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWV
                     PLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLF
                     LTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQA
                     QREAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLT
                     WLVYGRRKFSQK"
     gene            19782..23522
                     /gene="narZ"
                     /locus_tag="LSX49_002748"
     CDS             19782..23522
                     /gene="narZ"
                     /locus_tag="LSX49_002748"
                     /EC_number="1.7.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase Z subunit alpha"
                     /protein_id="HBL7169139.1"
                     /translation="MSKLLDRFRYFKQKGEIFADGHGQVMHSNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIR
                     SNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFY
                     DWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRY
                     SDMPMLVMLEPRDDGSYVPGRMVRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSI
                     GFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPV
                     LVRQLPVKNLTLADGSTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGE
                     QITGVPRQYIETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGC
                     VGQSGGGWAHYVGQEKLRPQTGWLPLAFAFDWNRPPRQMNSTSFFYNHSSQWRYEKVT
                     AQELLSPLADASKYSGHLIDFNVRAERMGWLPSAPQLGRNPLSLKAEADKAGLSPTEF
                     TAQALKSGDLRMACEQPDSGSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQG
                     EELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMN
                     TSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVCVGHLGKETDVVLQPLLHDS
                     PAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGK
                     GISWNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQ
                     ALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVH
                     ELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNF
                     LTPHQKWGIHSTYSENLLMLTLSRGGPIVWISETDARELTIVDNDWVEVFNANGALTA
                     RAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQL
                     AWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK"
     gene            23519..25063
                     /gene="narH"
                     /locus_tag="LSX49_002749"
     CDS             23519..25063
                     /gene="narH"
                     /locus_tag="LSX49_002749"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HBL7169140.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQDEWQGGWVRDVNGKIRPRLGSKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            25063..25758
                     /gene="narW"
                     /locus_tag="LSX49_002750"
     CDS             25063..25758
                     /gene="narW"
                     /locus_tag="LSX49_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HBL7169141.1"
                     /translation="MQILKVLGLLMEYPDELLWECKDDALALIRRDAPMLTDFALDLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLNCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILTLLGGRLKQREAPWYALFDALLQLAGS
                     PLSSDSVTKQIRSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            25755..26435
                     /gene="narI"
                     /locus_tag="LSX49_002751"
     CDS             25755..26435
                     /gene="narI"
                     /locus_tag="LSX49_002751"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HBL7169142.1"
                     /translation="MIQYLNVFFYDIYPYLCGTVFILGSWLRYDYGQYTWRAASSQML
                     DKRGMVLWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAVKQQMAMILGGICGVLT
                     LIGGAGLLVRRLTNPRIRATSSGADILILAILLIQCILGLTTIPFSAQHPDGSEMMKL
                     VGWAQSIVTFQGGASTHLDGVAFIFRVHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            26515..27408
                     /locus_tag="LSX49_002752"
     CDS             26515..27408
                     /locus_tag="LSX49_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HBL7169143.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRSKVLGLGNCTVWQTSLAGK
                     HRVTIEKQNDDYRISLEQGTPGFEPPLTGETRAAIINALHLTEDDILPGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLAALTAISKQIGCNGFFPFQIRPGKSETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGNVLRVKGHQGRALGRDGVIDVTVTIRDNQP
                     EKVTISGTAVILFHAEWAIDF"
     gene            complement(27504..28349)
                     /gene="nhoA"
                     /locus_tag="LSX49_002753"
     CDS             complement(27504..28349)
                     /gene="nhoA"
                     /locus_tag="LSX49_002753"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HBL7169144.1"
                     /translation="MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVL
                     QFNHHQHWQSMYRFDLCEQQQSDYVIGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTHYENGHAVEQRNLPDVASLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            28524..29093
                     /locus_tag="LSX49_002754"
     CDS             28524..29093
                     /locus_tag="LSX49_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL7169145.1"
                     /translation="MSQFIPVELHHASCLLNHGPTVMITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIEGNGKFGIVIPGVAATNWTWAVGSVSGREEDKFNCY
                     GIPVVRGPVLGLPLVEEKCLAWMECRLLPATSAQEKYDTLFGEVVSAAADARVFVEGR
                     WQFDDDKLNTLHHLGAGMFVTSGKRVTAG"
     gene            complement(29164..30300)
                     /locus_tag="LSX49_002755"
     CDS             complement(29164..30300)
                     /locus_tag="LSX49_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HBL7169146.1"
                     /translation="MELKKLMEHISIIPDYRQAWKVEHKLSDILLLTICAVISGAEGW
                     EDIEDFGETHLDFLKQYGDFDNGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDD
                     KDVIAIDGKTLRHSYDKSRRKGAIHVISAFSTMHSLVIGQIRTDEKSNEITPIPELLN
                     MLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNP
                     EHDSYAISEKSHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKE
                     PEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFS
                     GIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS"
BASE COUNT         7360 a         7844 c         7677 g         7579 t
ORIGIN      
        1 ggcgggatgg cgatgaaatg gcgttggcgc aagcgtatgg aagccgcagg caaacccacg
       61 gataaaccaa acctggtgtg cggtccggta caaatctgct ggcataaatt cgcccgctac
      121 tgggatgtgg agttgcgtga gatccctatg cgccccggtc agttgtttat ggacccgaaa
      181 cgcatgattg aagcctgcga cgaaaacacc atcggcgtgg tgccgacttt cggcgtgacc
      241 tacaccggta actatgagtt cccgcagccg ctgcacgatg cgctggataa attccaggcc
      301 gacaccggta tcgacatcga catgcacatc gacgccgcca gcggtggctt cctggcaccg
      361 ttcgttgccc cggatatcgt ctgggacttc cgcctgccgc gtgtgaaatc gatcagtgct
      421 tcaggccata aattcggtct ggctccgctg ggctgcggct gggttatctg gcgtgatgaa
      481 gaagcgctgc cgcaggaact ggtgttcaac gttgactacc tcggtggtca gattgggact
      541 ttcgccatca acttctcccg cccggcgggt caggtgattg cacagtatta tgaattcctg
      601 cgcctcggtc gtgaaggcta taccaaagta cagaacgctt cctaccaggt tgctgcttat
      661 ctggcggatg aaatcgccaa actggggccg tatgagttca tctgtaccgg tcgcccggac
      721 gaaggcatcc cggcggtttg cttcaaactg aaagatggtg aagatccagg atacaccctg
      781 tacgacctct ctgaacgtct gcgtctgcgc ggctggcagg ttccggcctt cactctcggc
      841 ggtgaagcca ccgacatcgt ggtgatgcgc attatgtgtc gtcgcggctt cgaaatggac
      901 tttgctgaac tgttgctgga agactacaaa gcctccctga aatatctcag cgaccacccg
      961 aaactgcagg gtattgccca gcagaacagc tttaaacaca cctgataacg tttaacggta
     1021 acggtgtccc gaaacgaagc cgtttcggga caatttccaa agtctgttca ctggcattag
     1081 caacggaaaa tattgttctg aatacgcttc agaacaaaac aggtgcggtt ccgacaggaa
     1141 taccgtttta gggggataat atggctacat cagtacagac aggtaaagct aagcagctca
     1201 cattactcgg attttttgcc ataacggcat cgatggtaat ggctgtttat gaatacccta
     1261 ccttcgcaac atcgggcttt tcattagtct tcttcctgct attaggcggg attttatggt
     1321 ttattcccgt gggactttgt gctgcggaaa tggctaccgt cgacggctgg gaagaaggtg
     1381 gcgtcttcgc ctgggtatca aatactctgg ggccgagatg gggatttgca gcgatctcat
     1441 ttggctatct gcaaatcgcc attggtttta ttccgatgct ctatttcgtg ttaggggcac
     1501 tctcctacat cctgaaatgg ccagcgctga atgaagaccc cattaccaaa actattgcag
     1561 cactcatcat tctttgggcg ctggcattaa cgcagtttgg tggcacgaaa tacacggcgc
     1621 gaattgctaa agttggcttc ttcgccggta tcctgttacc tgcatttatt ttgatcgcat
     1681 tagcggctat ttatctgcac tccggtgccc ccgttgctat cgaaatggat gcgaagacct
     1741 tcttccctga cttctctaaa gtgggcaccc tggttgtatt tgttgccttc attttgagtt
     1801 atatgggcgt tgaagcttcc gcaacccacg tcaatgaaat gagcaacccc gggcgcgact
     1861 atccactggc tatgttactg ctgatggtgg cggcaatctg cctaagctct gttggcggtt
     1921 tgtctattgc gatggtcatt ccgggtaatg aaatcaacct ctccgcaggg gtaatgcaaa
     1981 cctttaccgt tctgatgtca catgtggcac cggaaattga gtggacggtt cgcgtgatct
     2041 ccgcactgct gttgctgggt gttctggcgg aaatcgcttc ctggattgtt ggtccttctc
     2101 gcgggatgta tgtcacagcg cagaaaaacc tgctgccagc ggcattcgct aaaatgaaca
     2161 aaaatggcgt accggtaacg ctggtcattt cgcagttggt gattacttct atcgcgttga
     2221 tcatcctcac caataccggt ggcggtaaca acatgtcctt cctgatcgca ctggcgctga
     2281 cggtggtgat ttatctgtgt gcttatttca tgctgtttat tggctacatt gtgttggtgc
     2341 ttaaacatcc tgacttaaaa cgcacattta atatccctgg tggtaaaggg gtgaaactgg
     2401 tcgtggctat tgtcggtctg ctgacttcaa ttatggcgtt tattgtttcc ttcctgccgc
     2461 cggataacat ccagggtgac tctaccgata tgtatgttga attactggtc gttagtttcc
     2521 tggtggtact tgccctgccc tttattctct atgctgttca tgatcgtaaa agcaaagcga
     2581 ataccggcgt cactctggag ccaatcaaca gtcagaacgc accaaaaggt cacttcttcc
     2641 tgcacccgcg tgcacgttca ccacactata ttgtgatgaa tgacaagaaa cactaaccat
     2701 gtctgaatgc ttataagaca agggagcgat aattcatcgc tccctttttc gtgcttgttg
     2761 tcgtattgac ttaaccggga taagtacgag aatgagcgca catctgttta ccggaaacca
     2821 gcacatatgg atatctgctc ccgaaacgag aaattagcga ttagaagacc agcgatactg
     2881 gttgcactgg cacttttact gtgtagttgt aaaagcacgc ctccagagtc catggtgaca
     2941 ccaccagcgg gctcaaagcc accagccacg acgcaacaat cgtcacaacc gatgcgtggc
     3001 atctggctgg ccacggtgtc tcgcctcgac tggccaccgg tttcctcggt taacaatagt
     3061 aaccccacca gccgggcacg tgtacaacaa caggcgatga tcgacaaact ggatcatctg
     3121 caacgtctcg gcataaacac ggtctttttt caggtcaagc cggatggtac cgccctgtgg
     3181 ccatcgaaaa ttttgccgtg gtccgatctt atgaccggta agattggtga aaatccgggt
     3241 tacgatccgc tgcaatttat gctcgacgaa gcccacaagc gtgggatgaa agtacacgcc
     3301 tggtttaacc cctatcgcgt atcggttaat acgaagcccg gtactatcag ggaactgaat
     3361 agcaccctgt ctcaacaacc ggccagcgtc tatgtgcaac accgcgactg gatcagaacg
     3421 tccggcgatc gctttgtcct cgacccgggc atccctgagg ttcaggactg gatcacatca
     3481 atagttgcgg aagtggtttc ccgctatccg gtagatggcg tgcagtttga tgactatttc
     3541 tatactgagt caccaggttc acggctaaat gataacgaaa cgtaccgcaa atacggaggc
     3601 gcatttgcgt caaaagcaga ctggcggcgc aacaataccc agcagttaat tgcgaaggtt
     3661 tcgcacacca ttaaaagcat taagccggaa gtcgaatttg gcgttagccc ggcaggcgtg
     3721 tggcgtaacc gatcacacga tccgctcggt tccgataccc gaggcgcggc agcctatgac
     3781 gaatcctacg ctgatacccg tcgatgggtg gaacaagggt tgctggatta cattgctccc
     3841 caaatttact ggccattctc acggagtgcc gcgcgttatg acgtgttggc aaaatggtgg
     3901 gcggatgtcg ttaaaccgac caggacccgc ctgtatatcg gtatcgcctt ctataaagta
     3961 ggagaaccgt caaagataga gccagactgg atgattaacg gcggcgtacc ggaactgaaa
     4021 aagcagctcg atcttaacga tgctgtgccg gaaattagcg gcacaatctt gttccgtgag
     4081 gactatctga ataaaccgca gactcaacaa gcggtcagct atctgcaaag tcgttggggc
     4141 agttaaactc ccattcttac tttgtaacaa gccggtgctt tacccactgg cttgttaccc
     4201 tcttgaacta tcccactagc aatcatgctt aaatacgtca aattaaccac gcaattaacc
     4261 acacttagtt aaacagccat aatcccccta ataaaaatgt atgaatatga aaaaacatac
     4321 gatattcgct gtcaccgaaa aataattacg atgggctata ctcttctgaa gaacagtagc
     4381 gtagattgaa actgtcctaa gtcgcttatt tcttttcagt atatcttcat atttcaggag
     4441 aatatggtgc agttagccaa tcccgcacgt tgtgtttggt tgattttggc ctgcggttta
     4501 accataaagg tcgacattat tttaaagccg caaacggcga ggatattgcc ctctcacttt
     4561 ccatcggtgc cgccatgttt aatggtcatc ctgactatga gcgcctcatt caaatagccg
     4621 atgaagctct gtatatcgca aaagacgagg tagaaaccgt gttgaactct gtaaagccag
     4681 tctttagatg cgccaggatg cagaggtaat catgaagcta accgatgcgg ataatgccgc
     4741 cgatggcatt tttttccccg cccttgagca aaatatgatg ggcgcggtgt taattaacga
     4801 aaatgatgaa gtgatgtttt tcaaccccgc cgcagagaag ctctgggggt acaaacgtga
     4861 agaagtcatt ggcaataaca ttgatatgct gattccgcgg gatttgcgtc ctgcgcatcc
     4921 tcaatacatt cgtcacaacc gtgaaggtgg taaagcgcgc gtcgagggga tgagtcggga
     4981 gctgcagctg gagaaaaaag acggcagtaa aatctggacc cgttttgcgc tatcgaaagt
     5041 gagcgccgag gggaaagttt attacctggc gctggtacgg gatgccagcg tagaaatggc
     5101 gcaaaaagaa cagacccgac aattgattat tgccgttgac catctcgacc gaccggtgat
     5161 tgtcctcgat ccggaacgcc atattgtgca gtgcaatcgc gcatttaccg aaatgtttgg
     5221 ttactgcatt aacgaagcca gcggtatgca gcccgataca ctcctgaaca ttccagaatt
     5281 ccctgctgat aaccgtattc gtttacagca gttgctatgg aaaaccgccc gcgatcagga
     5341 cgaatttctg ctgttgacgc gcaccggtga aaaaatctgg attaaagcct ctatcagccc
     5401 ggtttatgac gtgctcgcgc atctgcagaa cctggtaatg acattctcgg atatcaccga
     5461 agaaaggcaa atccgccagc ttgaaggcaa tattctcgcc gccatgtgca gcagcccacc
     5521 atttcatgaa atgggggaaa tcatttgtcg taatatcgaa tctgttctca acgaatcgca
     5581 tgtttctctg ttcgcgctgc gcaacgggat gccgatacac tgggcgtcat cttcgcacgg
     5641 tgcagaagtt caaaatgcgc aaagctggtc agcgaccatt cgtcagcgcg atggcgcgcc
     5701 tgcggggatc ctgcaaatta aaacctcgtc aggagcagaa accagcgcct ttatcgaacg
     5761 cgtggcagat atcagccagc atatggccgc gctggcgctg gaacaggaaa aaagccgtca
     5821 gcatattgaa caactcatcc aatttgatcc gatgaccggt ctgccaaatc gcaataacct
     5881 gcacaattac ctcgatgacc tggtcgacaa agccgtctct ccggtggtgt atctcatcgg
     5941 tgttgaccat attcaggatg tgattgatag ccttggctat gcgtgggccg atcaggcatt
     6001 gctggaagtg gtcaatcgct ttcgtgaaaa actcaaaccg gatcagtatc tctgtcgtat
     6061 tgaaggtgcg tcttttgtcc tcgtgagcct ggaaaacgat gtcagtaaca ttacccagat
     6121 cgccgatgag ctacggaatg tggtcagcaa gccgataatg attgacgata aaccattccc
     6181 gctcaccttg agcattggca tcagctacga cgtgggtaaa aaccgcgatt acctgctctc
     6241 cactgctcac aatgcaatgg attttattcg caaaaatggc ggtaacggct ggcagttctt
     6301 cagcccggcg atgaacgaaa tggtaaaaga gcgtttggtt ttaggcgcag cgctaaaaga
     6361 agcgattagc aataaccaac ttaaactggt ttatcagccg caaatcttcg cagaaacggg
     6421 tgaactgtac ggcatcgaag cccttgctcg ctggtacgat cccctgcatg gtcatgtgcc
     6481 cccttcacgg tttattcctc tcgcagaaga gattggtgaa atcgaaaata ttgggcgctg
     6541 ggtcatcgcg gaagcttgcc gtcagttagc agaatggcgt agccagaata ttcatatccc
     6601 ggcgttatcc gttaacttgt ctgcgctgca ctttcgcagt aatcagctgc ctaatcaggt
     6661 atctgacgca atgcacgcct ggggtattga cggccaccag ctgacggtgg aaatcacgga
     6721 aagcatgatg atggaacacg ataccgaaat ctttaagcgc attcagatcc tgcgcgatat
     6781 gggcatcggt ttatcggtag atgattttgg tacgggcttt tccggattat cccgcttagt
     6841 cagtcttccg gtaacggaaa tcaaaattga caaaagtttt gtcgatcgtt gtctgactga
     6901 aaaacgcatc cttgccttac tcgaagccat taccagcatt gggcaaagcc tcaatttaac
     6961 cgtcgtggcg gaaggcgtcg aaaccaaaga gcaatttgag atgctacgca agatccactg
     7021 tcgcgttatt cagggatatt tcttttcccg ccccctgccc gccgaagaaa ttccaggctg
     7081 gatgagcagc gtgttaccgc tgaaaatctg ataaattcct ctcgcccgca ctcgcgggtt
     7141 tttatttaac gtgacactgt cacttaaatg ctgtgatttc cgctacgttt agttggacaa
     7201 cgacaacgca tagccatgtc agaacaatcc cttctcagcc tgatgtgatt gtgctgacgc
     7261 atcaggcatt cacgcgcctg acgcgtcatc cggcaacgct ttacgatttc aactggtaat
     7321 ccagcgtaat ttccgctttc agtacctgag aaaccgggca tcctgctttt gctttctgga
     7381 taatgccgtc aaaggtggag gcatcaatac ccggcaccgc aacttcgctc ttcagtgcga
     7441 ttttagtaat cgcaaaaccg gcatccactt tatccagcga gacatcggcg gtggtatcaa
     7501 tcgatgttgg cgtgaatccc gcttccccca gcattaatga aagcgccatt gagaaacatg
     7561 cggcatgcgc tgcgccaatc agttcttcag ggttggttcc tttttcgcct tcaaaacgcg
     7621 tgttaaatcc atacggctgt tggttcagca cgccgctctc agtagatact gttcccttcc
     7681 cgcgtttgat atcgccttcc caatgtgcct gacctttctt atggattgtc attgttgctc
     7741 tcctgtgggc ttaaaaggaa attatagact acgtgagaaa cagcacgagg ataagcagga
     7801 taatccgaat aaaatccggc gaaaatataa tttctgcact taaattaaat ttccacaata
     7861 gataaccgga aatatataac ccaagagata ttgcatcaat atcaatcaac tcatcacaat
     7921 aataatacct atcaatatca tggagttaaa atataaaatc atcaaccagg actaatctta
     7981 acaacgaagc agcaaatatt tgccatgctg aatgtgcttt ataaatctgc gatccgtagc
     8041 agacaccata aatacacaga cacggagaat cactatgttt acttattatc aggcagaaaa
     8101 ttcaacagca gaacccgctc tggttaatgc cattgagcaa ggccttcggg cagagcacgg
     8161 tgttgtcact gaagatgaca ttctcatgga gctgaccaaa tgggtggaag cttctgataa
     8221 cgacatcctc agtgatatct accagcaaac gatcaattat gtggtcagtg gtcagcaccc
     8281 tacgctttaa ggtgctatgc ttgatcggca acctaattta ggggtttagc acgtgtttct
     8341 tcgctacggc gatgttgtcc ttaaaactag caacaggatt gaggagttaa aatgaaatcg
     8401 aaccgtcagg cacgtcatat tcttggactg gaccataaaa tttctaacca gcgcaaaata
     8461 gttaccgaag gtgacaaatc cagcgtggta aataatccca ccggcagaaa acgccccgct
     8521 gaaaagtaat tcataaccat cagtcctcaa tgacgattaa acaccattgc ctgcgcaatg
     8581 gtgtttttgt ttttatctgc tttatacttg gtgccgacgc cctggcggta atgcaaagac
     8641 gataaaagcc cccagggatg gatattcaaa aaagagtgag tgacatggaa ccaaaaacaa
     8701 aaaaacagcg ttcgctttat atcccttacg ctggccctgt attgctggaa tttccgttgt
     8761 tgaataaagg cagcgccttc agcatggaag aacgccgtaa cttcaacctg ctggggttac
     8821 tgccggaagt ggtcgaaacc atcgaagaac aagcggaacg agcatggatc cagtatcagg
     8881 gattcaaaac cgaaatcgac aaacacatct acctgcgtaa catccaggac actaacgaaa
     8941 ccctcttcta ccgtctggta aacaatcatc ttgatgagat gatgccagtc atttacaccc
     9001 caaccgtcgg cgcagcctgt gagcgttttt ctgagatcta ccgccgttca cgcggtgtgt
     9061 ttatctctta ccagaaccgc cacaatatgg acgatattct gcaaaacgta ccaaaccata
     9121 atatcaaagt gattgtggtg actgacggcg aacgtattct ggggcttggt gaccagggca
     9181 tcggcgggat gggcattccg atcggtaaac tgtcgctcta taccgcctgt ggcggcatca
     9241 gtccggccta tacccttccg gtggtgctgg atgtcggcac caacaaccaa cagctgctta
     9301 acgatccgct gtatatgggc tggcgtaatc cgcgtatcac tgacgatgaa tactatgaat
     9361 tcgttgatga atttatccag gctgtgaaac aacgctggcc ggacgtactg ttgcagtttg
     9421 aagacttcgc acaaaaaaat gcgatgccgt tacttaaccg ctatcgcaat gaaatttgtt
     9481 cttttaacga tgacattcag ggcaccgcgg cggtaacagt cggcacactg atcgcagcca
     9541 gccgcgcggc aggcggtcag ttaagcgaga aaaaaatcgt cttccttggc gcaggttcag
     9601 cgggatgcgg cattgccgaa atgatcatcg cccagaccca gcgcgaagga ttaagcgagg
     9661 aagcggcgcg gcagaaagtc tttatggtcg atcgctttgg cctgctgacc gacaagatgc
     9721 cgaacctgct gcctttccag accaaactgg tgcagaagcg cgaaaatctc agtgactggg
     9781 ataccgacag cgatgtgttg tcactgctgg atgtggtgcg taatgtaaaa ccagatattc
     9841 tgattggcgt ctcaggacag accgggctgt ttacggaaga gatcatccgt gagatgcata
     9901 aacactgtcc gcgtccgatc gtgatgccgc tgtctaaccc gacttcacgc gtggaagcca
     9961 caccgcagga cattatcgcc tggactgaag gtaacgcgct ggtcgccact ggcagtccgt
    10021 ttaatccagt ggtatggaaa gataaaatct accctatcgc ccagtgtaac aacgccttta
    10081 ttttcccggg catcgggctg ggtgttattg cttccggcgc gtcacgtatc accgatgaga
    10141 tgctgatgtc ggcaagtgaa acacttgctc agtattcgcc gctggtcctg aacggcgaag
    10201 gtctggtact accggaactg aaagatattc agaaagtctc ccgcgcaatt gcctttgcgg
    10261 ttggcaaaat ggcgcagcag caaggcgtgg cggtgaaaac gtctgccgaa gctctgcaac
    10321 aggccattga tgataatttc tggcacgccg aataccgcga ctaccgccgt acctccatct
    10381 aagcctgcgc ccggtagtga gggctaccgg gcaattttcc tctccctttt tcagatctca
    10441 tccatactgg gtagtggcga ataaatctca tttgcctcac ctgctatgca gaacatcatc
    10501 cgaaaaggag gaactatgaa ggctgcagtt gttacgaagg atcatcatgt tgacgttacg
    10561 gataaaacac tgcgctcact gaaacatggc gaagccctgc tgaaaatgga gtgttgtggt
    10621 gtatgtcata ccgatcttca tgttaagaat ggcgattttg gtgacaaaac cggcgtgatt
    10681 ctgggacacg aaggtattgg tgtggtggca gaagttggcc ctggtgttac ttcattaaaa
    10741 ccaggcgatc gtgccagcgt ggcgtggttc tatgaaggat gcggtcattg cgaatactgt
    10801 aacagtggta acgaaacgct ctgccgttca gttaaaaatg ccggatacag cgttgatggc
    10861 gggatggcgg aagagtgcat cgtggtcgcc gattacgcgg taaaagtgcc agatggtctg
    10921 gactcggcgg cggccagcag cattacctgt gcgggggtca ctacctacaa agccgttaag
    10981 ctgtcaaaaa ttcgtccagg acagtggatt gctatctacg gtcttggcgg tctgggtaac
    11041 ctcgccctgc aatacgcgaa gaatgtcttt aacgccaaag tgatcgccat tgatgtcaat
    11101 gatgaacagt taaaactggc aaccaaaatg ggtgcagatt tagcgattaa ctcacgcacc
    11161 gaagacgccg ccaaaattgt gcaggagaaa gccggtggcg ctcacgcagc ggtggtgaca
    11221 gcggtagcta aagctgcgtt taactcggcg gtggatgctg tccgtgcagg tggtcgtgtc
    11281 gtggctgtcg gtctgccgcc ggagtctatg agcctggaca tcccacggct ggtgctggat
    11341 ggtattgaag tggtcggttc gctggtcggc acgcgtcagg atctaaccga agccttccag
    11401 tttgccgccg aaggcaaagt ggtgccgaaa gtcgccctgc gtccgttaga ggacatcaac
    11461 accatcttta ccgagatgga agaaggcaaa atccgtggcc gtatggtgat tgatttccgt
    11521 cgctaagagg tctttgctgc gactgccatg ttcgggtcgc agcctgtttc gcgagacgct
    11581 ttccgtaatt tcactcttct tcttttcctc ccccatattt cccctcacaa ttcgcgaaaa
    11641 cgtagcgaaa tttgttgcgc tgcacggaac aatagtgata gtgttccttt tgagggaaca
    11701 aggatgaaga gatgataatg aatttcagac acaagggatt gcgtgacttg tttcttctcg
    11761 gcaaaacctc cggcgttata ccgacgcaag tcaaacgatt acgccaccac tcgctgtgat
    11821 tgatgcagca tgctgtcttg ctgatatcga tatgcccggt taccgactac atccgttaag
    11881 cggcgatcgc gatggaattt gggcgatatc tgtctcgggc aactggcgaa tcacatttga
    11941 attcgtcaat ggcgatgcat acatactgga ttacgaggac tatcactgat gaaaatggcc
    12001 aatcatcccc gcccggggga cattattcag gaatcactgg acgaacttaa tgtcagcctg
    12061 cgcgagtttg ccagagcaat ggaaattgcg ccctcaacgg caagccgatt gctgaccgga
    12121 aaagcagctt tgacgccaga aatggcaata aaactttccg tggtgatcgg cagttcgccg
    12181 caaatgtggc tgaatctgca aaatgcctgg agtctggcag aggcggaaaa aacggtggat
    12241 gtgtcgcgac tgcgccgtct ggttacgcaa taaaaaatgg cgcttcttaa agcgccattt
    12301 tcagcttaaa gttcaaaaga gattatatcc cttcttcact ctcttttttc gcttctgcct
    12361 tctcgatttc acgataccag cgcggatggt gtttcttcgc ccagcgacgg ctcaccttcc
    12421 cttcgatcat ccctttaatc gatcctttca cccagaatgc catatacata tggatcagga
    12481 tggcgtggat caggatgata cccgcagccg catggatcag caggctataa cggacaacct
    12541 gtatcgggaa gtactgcgca aagtacggac gccagataat cactccggtc accagcagca
    12601 cgaaaatcat gctcatgatt gaccagaaca tcatcttttg cccggcgttg tacttaccga
    12661 catccgccac tttgtgctca ttgcctttta atacttcgac aatgttcaac agccacggaa
    12721 tatctttctt atccgggatg ttgtgatgca caaaacgcac aaacataaac atcagcgcga
    12781 cgaaaatcgc aatgccgaag aacgggtgca aaatgcgtcc catctgcggc gtaccgaagg
    12841 tttgcgtcag ccattgcagc gtcgggaaga agaacgaaat cccggacagc gccaccagga
    12901 agaagcaaat caccacggtc cagtgacagg cgcgatcaat aaatttggtg cgcacaatca
    12961 ttttcgactt actcatgatt tccctcctcc tcatcgtcca cttccttatt cgggccaata
    13021 ccgatgtagt ggaaaatcaa cccggcaaaa gtggcaataa agccagccgc tgccagcggt
    13081 ttcaacgcgc ctttccacag gcttaccgag gtatcgatct tcggatcttt cggcagacca
    13141 tgatacagct ccggctgatc ggcgtgatgc agcacgtaca taacgtgcgt accaccgacc
    13201 ccttccgggt tgtagacgcc agcatgttcg taaccacgcg ctttcagttt cgccacgcgc
    13261 tgttccgcca gctccagcat ctccttcttg gtgccgaagt ggatagcccc ggtcggacag
    13321 gttttcacac aagccggttc ctggccgacg ctgacgcgat cgacacagag cgtgcattta
    13381 tatacccggt tatcctcttt gttgaggcgc ggaatattaa acggacaccc ggcaatgcag
    13441 taaccacagc cgatgcagtt ttccgactgg aaatcgacaa tcccgttagc gtactgaatg
    13501 attgcaccag cagacgggca tgccttcagg cagcccggat cttcacagtg catacagccg
    13561 tctttacgga tcagccactc cagcttgccg ttctgttcgg tttcgctaaa gcgcatcacc
    13621 gtccaggact tggcgctcag atcggcgggg ttatcgtaaa ccccgacgca gtgccccact
    13681 tcatcacgga tgtcgttcca ctccgaacac gccacctgac aggctttaca gccgatacaa
    13741 gtggaaacgt cgataagttt cgcgacttct gctttgtaat cacgcacctg agaaggcggc
    13801 gtgatggagt tagttgcgga ccttttgata atgtcctgcg tttccatagc catctgttcg
    13861 cccccttacg ccttctcgat gtttactaag aacgctttat attccggcgt ttgcgagttt
    13921 gcatcaccga cattcggcgt cagagtgtta gcgatataac ctttacgcgc gacaccttca
    13981 aagccccagt ggattggaat acccaccgtt tcaacctgct gaccgtttac attcagcggt
    14041 ttcagacggc gcgttaccac agccaccgcg cggataaagc cacgcttgct ggagacagtg
    14101 acacgatcgc cattggcaat gcctttcgcc gccgccagcg tttcgctgat ttccacaaac
    14161 tgttccggct gagcaattgc gttgagcaat gcgtgcttgg tccaggtgtg gaagtgctcc
    14221 gtcagacgat aggtcgtacc cacatacggg aactgctctt ttttacccat ccgcagcgcg
    14281 tcttgttcat acagacgaac aaccgggtta gacaccacgt tcggatgcaa cgggttagtg
    14341 cccagcggcg tttcaattgg ctcgtagtgt tccgggaacg gaccttccgc cattttgttg
    14401 atggcaaaca ggcgtcccat cccttccggt tgcatgataa acggcccggt tggcgtaccc
    14461 ggcgcggcat tgccgaagtc cggaatatcg ttacccgtcc acttgctacc gttccactgg
    14521 atcagcatcc gtttcggatc ccacggttta ccgttgatat ccgccgaagc acggttgtag
    14581 agtacgcgac ggttgagcgg ccacgcccag gcccatccca gcgtattccc cagaccggac
    14641 gggtcggagt tatcgcggtt agccatctgg ttgccctgct cggtccagct accggtgtag
    14701 atccagcaag aagatgcggt tgtaccgtca tcacgcagat gtgcaaagct actcagcaac
    14761 tgacctttct tcgcaatcag cacgccatta gcgtcataga gatcttccag cgcatagccg
    14821 ttattctctt tcgccacttc atcagactgc ggttcgtgcg gctgcttgta gttccagctc
    14881 atcttcatca gcggttctac gcctttacca ccttcggcct ggtacagctc gcgcagatga
    14941 tggtagatac ccgccagaat ttcgccgtcg ttacgtgctt cgcccggcgc gtcctgacct
    15001 ttccagtgcc actgcaacca gcgaccggag ttagcgatag aaccatcttc ttcagcaaag
    15061 caggtcgaag gcagacggaa tacttcagtc tgaatagatg ccggatcgac atcgttcgac
    15121 tcgccgtggt tctgccagaa ggtagaggtt tcagtcacca gcggatcgat aaccaccatg
    15181 tacttcagct tgctcaggca gctcaccact ttgtttttgt ccgggaagga cgcaaccggg
    15241 ttaaagccct ggcagaaata accggtgact ttaccttcat ccatcatgtt gaaatacttg
    15301 atgacgtcgt aggtctggtc ccacttcggc agccagtcgt agccccagtt gttctctttc
    15361 tgcgcggcat cgccgtagaa agatttcatc aggctaacga aaaacttcgg atagttgctc
    15421 cagtagttca cctgatcagc cagcgtcgct ttcggcgtgt tcgcttccag atacgactgc
    15481 aaatcaacct gtttttctga cggcagcgtc agataacctg gcaggctggt agagagcagg
    15541 cctaagtcag tcaggccctg aatgttggag tgaccacgca atgcgttcac gccgccaccg
    15601 gccataccca tgttaccgag cagcaactgg atcatcgcca tcgtacggat gttctgcgca
    15661 cccacggtgt gctgcgtcca gcccagcgcg tacaggaagg tggttgtgcg atccggtgcg
    15721 ctggtggagg ccagcacttc acacactttc aggaagtcgg cttttggcgt accgcaaatg
    15781 ttttctacta cgtccggcgt gtagcgggaa acgtgcgctt tcagcagatt ccatacacag
    15841 cgcggatgag tcagcgtgtc atcgcgtttc gcatagccgt tttcatcgaa ctgatagttc
    15901 caggacgact tatcgtattg acgtttttca gcgtcgtagc cgctgaacag accgtcttcg
    15961 aaagcaaaat catcacgcac cagcaggctg gcgttggtgt aatgcttaac gtattcggcg
    16021 ttgattttgt tgttttcgat caggtagcgc aaaacgccag acaggaacgt aatgtccgta
    16081 ccggaacgaa taggtgcgta aatatccgcc acagaagcgg tacgcgtaaa acggggatcg
    16141 acaacgatca aggttgcatc gttgttgttt ttcgcttcca tcgcccagcg gaaaccgacg
    16201 ggatgcgctt cagcagcgtt accgcccatc accattacga cgttagcgtt tttgatatcc
    16261 acccagtggt tggtcatcgc accgcgacca aatgttggag caagacttgc taccgttggt
    16321 ccgtgtcaga cgcgcgcctg gttgtctacc gccagcatcc cgagggagcg ggcaaatttt
    16381 tgagtcagca tcccggtttc gttgctggca ccggaagcac acagcatacc ggtagaaagc
    16441 caacggttta ccgttacgcc ctgctcgttc ttttcaataa agttagcgtc acggtcggct
    16501 ttcatcagct tcgcaatacg ggagaatgct tcttcccagc taatgcgctg ccatttgtca
    16561 gaacctggcg cacgatattc cgggtagcgc agacggtttt cgctgttgac ataatccagc
    16621 aaaccggccc ctttcgggca cagcgcacca cgacttaccg gatgatccgg gtcaccttca
    16681 atgtgataaa tcgcttctct ggcgtttttc gcgccatcac ccaggctata catcaatagc
    16741 ccgcaaccta cggaacagta tgtgcaggtg ttacggatct ctttcgcgcg taataatttg
    16801 tagtttcgcg cctgagccag tgcttgcttc ggggcaaagc ccaatgctgc tactgttgtt
    16861 cccgccatac cgcccgcgca gattttaaaa aattgtctgc gactgacgtc cattgctttc
    16921 ctcttttttc aggggtatta ctgcgcgagg aaactaacag taaaattctg aatctttttg
    16981 cgcgaaatca aaaagaacac gtgtttgcca caaaataatc cgcctgcgca aattgaccta
    17041 cctcaatagc ggtagaaaaa cgcaccactg cctgacaggc cagttaaaaa aatgctataa
    17101 aattcagctt aatttttaac ggcaagagag acaaaacagc gagcatgaca cgtcaaaaag
    17161 caacgctcat agggctaata gcgatcgtcc tgtggagcac gatggtagga ttgattcgcg
    17221 gtgtcagtga gggactcggc ccggtcggcg gcgcagctgc tatctattca ttaagcgggc
    17281 tgctgttaat cttcacggtt ggatttccgc gtattcggca gatcccgaaa ggctatttac
    17341 tcgccgggag tctgttattc gtcagctatg aaatctgtct ggcgctttcc ttagggtatg
    17401 cggcgacccg tcatcaggcg attgaagtgg ggatggtgaa ctatctatgg cccagcctga
    17461 caattctctt tgccattctg tttaatggtc agaaaaccaa ctggctgatt gtaccaggat
    17521 tattattagc cctggtcggc gtctgctggg tgttaggcgg tgacaatggg ttacattatg
    17581 atgaaattat caataatatc accaccagcc cattgagtta tttcctggcg ttcattgggg
    17641 cgtttatctg ggcagtctac tgcacagtaa cgaataaata cgcacgcgga tttaacggaa
    17701 ttaccgtttt tgtcctgcta acgggagcaa gtctgtgggt ttactatttt cttacgccac
    17761 aaccagaaat ggtatttagc acgcccgtca tgattaaact catctctgcg gcatttacct
    17821 taggatttgc ttatgctgca tggaatgtcg gtatattaca tggcaacgtc accataatgg
    17881 cggtaggttc gtattttacg cccgtccttt cctcagcgct tgcagccgtg ctgctcagcg
    17941 ccccgctgtc gttctcgttc tggcaaggcg cgctaatggt ctgcggcggt tccctgctct
    18001 gctggctggc gacacgtcgt ggctaaaata attgtcgggt ctacggcccg gcagttaatc
    18061 agataaattc tgacaatatt aaaaaataaa tttcaaatac cagaaagtca ttttagttac
    18121 atttagtaac acatatctgt ctgtttaatc cacattctgc ccccgcagtt acgctttctt
    18181 atctattctt ctaatcagca cttcacctga ttcatcctta attctaataa ctggctattg
    18241 cgccttacct cctgttttgt ctttttttca ttaccaatgt gtgcatgtga ggaacaatat
    18301 ggcactgcaa aatgagaaaa atagtcgtta tcttttacgc gactggaaac cagaaaatcc
    18361 ggccttctgg gaaaataaag gaaagcatat tgcacgaaga aacctctgga tatcagtcag
    18421 ttgtctactt cttgccttct gtgtctggat gctatttagc gcagttactg ttaatctcaa
    18481 taaaatcggt tttaatttta ctaccgatca actcttttta ttaaccgcat taccctccgt
    18541 ttctggcgca ttattgcgtg tcccctactc ctttatggtg cctatattcg gtggacgccg
    18601 atggacggtt tttagtactg caatcctgat tattccttgc gtctggctcg gaattgccgt
    18661 gcagaatccg aatactcctt ttgggatatt tatcgttatc gctttgctat gcggttttgc
    18721 aggtgcgaac tttgcttcga gcatgggcaa tatcagtttc ttctttccaa aagccaaaca
    18781 agggagcgct cttgggatta atggcggatt aggaaactta ggtgtaagtg taatgcagct
    18841 ggttgcaccg ctggtcattt ttgtccccgt atttgccttt ctcggcgtca atggcgtacc
    18901 gcaggccgac ggttcggtga tgtcgctggc gaatgccgca tggatttggg tgccattact
    18961 ggcgattgcc acgatcgccg cctggtcagg gatgaatgat atcgccagtt cacgcgcctc
    19021 aattgccgac cagctccctg tcttacaacg cctgcatctc tggctgctga gcctgcttta
    19081 ccttgccacc ttcggttcgt ttatcggttt ttctgcgggt tttgccatgc tggcaaaaac
    19141 ccagttcccg gatgtgaata ttctgcgcct ggcgttcttt ggcccattta tcggtgccat
    19201 cgcgcgatcg gttggtggtg ctatttccga taaattcggc ggcgtgcggg tgacgttgat
    19261 caacttcatt tttatggcga ttttcagcgc cctgctgttc cttaccttac cgggcacagg
    19321 ctccggtaat ttcatcgcat tttacgccgt atttatgggg ctgtttctga ccgcgggtct
    19381 gggaagtggt tctactttcc agatgatcgc cgtcatcttt cgccagataa caatttatcg
    19441 ggtgaagatg aaaggcggta gtgatgagca agctcaaaga gaagccgtca ccgaaacggc
    19501 agccgctctg ggctttatct cagccattgg cgcagtgggc ggctttttta ttccgcaggc
    19561 gtttggcatg tcgctcaata tgaccggctc tccggtgggc gcgatgaaag tgtttttaat
    19621 cttctacatc gtttgtgtgc tactgacctg gctggtttat ggtcggcgga agttcagcca
    19681 aaaataagag atcgatgcct gacacgtctt atcaggctac aaccgtgtcg catccgacaa
    19741 ggcatcagat cccaattcat tcctggagca ggagttatgt catgagtaaa cttttggatc
    19801 gctttcgcta cttcaaacaa aagggcgaaa tctttgccga tggtcacgga caggtgatgc
    19861 atagcaaccg cgactgggag gacagctatc gccagcgttg gcagttcgac aaaatcgtgc
    19921 gttccaccca cggtgttaac tgtacaggct cctgtagctg gaaaatctac gttaaaaatg
    19981 gtctggtgac ctgggaaatc caacagaccg attacccgcg cactcgccct gacctgccga
    20041 atcacgaacc tcgcggctgc ccgcgtggcg caagttactc ctggtatctc tacagcgcga
    20101 accgcctgaa atacccgctc attcgtaaac gactgattga actgtggcgc gaagccctca
    20161 agcaacacag cgatccggta ctggcgtggg catcgattat gaacgatccg caaaagtgcc
    20221 tgagctacaa acaagtgcgt ggacgcggtg gttttatccg ctccaactgg caggagctaa
    20281 atcagctgat tgccgccgct aacgtctgga ccatcaaaac ttacggcccg gatcgcgttg
    20341 ccggtttctc gccgattccg gcgatgtcga tggtttctta cgctgccgga acacgctatc
    20401 tgtcgctgtt aggtggcacc tgtttaagct tctacgactg gtattgcgac ctgccgcccg
    20461 cctcgccgat gacctggggc gagcaaaccg acgtaccgga atctgccgac tggtataact
    20521 ccagttacat catcgcctgg gggtctaacg taccgcagac acgtacgccg gacgcccatt
    20581 tctttaccga agtacgctac aaaggcacta aaaccatcgc cattacccct gactactctg
    20641 aagtggccaa attgtgcgac cagtggctgg caccgaaaca aggcactgat agtgccctgg
    20701 caatggcaat gggccatgtc attttaaaag agtttcatct cgataatccc agcgattatt
    20761 ttatcaacta ctgccgccgc tacagcgaca tgccgatgct ggtaatgctg gaacctcgcg
    20821 acgacggcag ctacgttccc gggcgcatgg tccgcgcatc tgacctggtg gatggactgg
    20881 gcgaaagcaa taatccgcag tggaaaaccg tggcagttaa taccgcaggt gaattggtag
    20941 tgccgaacgg ttcgattggt tttcgttggg gagaaaaagg caaatggaac ctggaatcca
    21001 ttgccgccgg tacggaaacc gaattgtcgt taaccctgct cggtcaacat gacgccgttg
    21061 caggcgtggc cttcccctac tttggaggca ttgaaaatcc gcattttcgc agcgtaaaac
    21121 acaatcctgt cctggtgcgc caattgcccg ttaaaaatct gacattagcc gatggtagca
    21181 cctgtccggt ggtcagcgtt tatgatctgg tactggcaaa ttacggcctc gatcgcgggc
    21241 tggaagatga aaacagcgcg aaagattacg ctgaaatcaa accttacacc cctgcctggg
    21301 gcgagcaaat taccggcgta ccgcgccagt atattgaaac catcgcccgt gaatttgccg
    21361 ataccgctca taaaacgcat gggcgctcga tgattattct cggcgcaggt gttaaccact
    21421 ggtatcacat ggacatgaac taccgcggga tgatcaatat gctgatcttc tgcggttgtg
    21481 tcgggcaaag cggcggcggc tgggcgcact atgtcggtca ggaaaaactg cgcccacaaa
    21541 ccggctggtt gccgctggcc tttgcgttcg actggaaccg tccaccgcgc cagatgaaca
    21601 gcacctcgtt tttctacaat cactccagcc agtggcgcta tgaaaaagtc accgcgcagg
    21661 aattgctctc accgctcgcc gatgccagta aatacagcgg tcacctgatt gatttcaacg
    21721 ttcgcgccga acgtatgggc tggctccctt ctgcgccgca gctggggcgt aacccgctct
    21781 ccctgaaagc tgaagccgac aaggccggat tatcccccac agaatttacc gcccaggcgc
    21841 tgaaatcggg cgatttacgt atggcctgcg aacaaccaga tagcggcagc aatcatccgc
    21901 gtaatttgtt tgtctggcgt tctaacctgc ttggctcctc cggcaaaggc cacgagtata
    21961 tgcagaagta tctgctgggg accgaaagcg ggattcaggg agaggaactc ggtgccagcg
    22021 acgggatcaa accagaagaa gtcgagtggc aaactgcggc gattgaaggc aagctcgacc
    22081 tgctggtgac gctcgatttc cgcatgtcca gtacctgcct gttctccgat atcgttctgc
    22141 ccaccgccac ctggtacgaa aaagacgata tgaatacctc ggatatgcat ccgtttattc
    22201 atccgctttc tgcggcggtc gatccggcgt gggaatcacg cagcgactgg gaaatctaca
    22261 aaggtatcgc taaagccttt tcgcaagtgt gcgtggggca tctcggcaaa gaaaccgacg
    22321 tggtattaca accactgctg catgactccc cggcagagct ttcacagccg tgtgaagtgc
    22381 tcgactggcg caaaggcgag tgcgatctga ttccaggcaa aaccgcgccg aatattgtgg
    22441 cggtggagcg cgactaccct gctacctatg aacgctttac ctcgctcggg ccattgatgg
    22501 acaaacttgg caacggaggt aaagggattt cgtggaatac ccaggatgaa attgatttcc
    22561 tcggtaaact caattacacc aagcgtgatg gcccggcaca ggggcgtccg ctgattgata
    22621 ccgcgattga tgcctcagaa gtgattctgg cgctggcacc ggaaaccaac ggccatgttg
    22681 cagtcaaagc gtggcaagcg ctgggcgaga tcaccggacg cgaacatacc catctggcgc
    22741 tgcacaaaga ggacgagaag attcgctttc gcgatattca ggcgcagccg cgtaaaatta
    22801 tctccagccc cacatggtct ggtctggaaa gcgatcacgt ctcctataat gcgggataca
    22861 ccaacgttca tgagctaatt ccgtggcgca cactgtcggg ccgtcaacag ctttatcagg
    22921 atcatccgtg gatgcgtgcc tttggtgaaa gcctggtggc ttatcgcccg cctatcgaca
    22981 cccgcagtgt cagtgaaatg cgccaaatcc cgccaaacgg cttcccggaa aaagccctta
    23041 acttcctgac accgcaccag aaatggggca ttcactcaac ctacagtgaa aacctgctaa
    23101 tgctgacgct ctctcgcggt ggaccgattg tctggatcag cgaaaccgat gcccgtgaac
    23161 tgaccattgt cgataacgac tgggtggaag tgtttaacgc caatggcgcg ctgacggccc
    23221 gcgcggtggt cagccagcgt gtaccgccgg gcatgaccat gatgtatcac gctcaggaac
    23281 gcattatgaa tattcctggt tcggaagtaa ccggcatgcg cggcggcatt cataactcgg
    23341 tcacccgcgt ttgtccgaaa ccaacacata tgattggcgg ttacgcgcag ctggcctggg
    23401 gctttaacta ctacggcact gtcggctcta accgcgacga attcatcatg atccgcaaga
    23461 tgaagaacgt taactggctg gatgatgaag gtcgcgatca ggttcaggag gcgaaaaaat
    23521 gaaaatacgt tcgcaagtcg gcatggtgct taacctcgat aaatgtatcg gctgccatac
    23581 ctgttcggtg acctgtaaaa acgtctggac cggtcgcgaa ggcatggagt acgcatggtt
    23641 taacaacgtc gaaaccaaac cgggcattgg ttatccgaaa aactgggaag atcaggatga
    23701 gtggcaaggt ggctgggtgc gtgatgtgaa tggcaagata cgcccgcgtc tgggcagcaa
    23761 gatgggcgta ataaccaaaa ttttcgccaa cccggtagtg ccgcagattg acgattacta
    23821 cgaacctttc accttcgact acgaacattt gcatagcgcg ccggaaggca aacatattcc
    23881 caccgcccgt ccgcgttcac tgattgacgg caaacggatg gacaaagtga tctggggccc
    23941 aaactgggaa gaactgctgg gcggcgaatt tgaaaaacga gcccgcgacc gcaacttcga
    24001 ggccatgcaa aaggagatgt acgggcagtt tgaaaacacc ttcatgatgt acctgccgcg
    24061 cctgtgcgaa cactgcctca atcccagctg cgtggcgacc tgccccagcg gcgctatcta
    24121 caaacgcgaa gaagacggca ttgtgctgat tgatcaggat aaatgccgtg gctggcgttt
    24181 gtgcattagc ggttgtccgt acaaaaaaat ctacttcaac tggaaaagcg gcaagtcaga
    24241 aaaatgtatc ttctgttatc cgcgaattga gtccggtcag ccaacagtct gctccgaaac
    24301 ctgcgtgggt cgcatccggt atctgggcgt gctgctctac gacgccgacc gcatcgaaga
    24361 agcagcgagt accgaacgag aggtcgatct ctatgaacgc cagtgcgaag tgttcctcga
    24421 tccgcacgat ccctcagtga tcgaagaagc cctgaaacaa ggtattccac aaaacgtgat
    24481 tgacgctgcc cagcgttcgc ctgtctacaa aatggcgatg gactggaaac tggcgctacc
    24541 gctgcaccct gaataccgca ccctgccgat ggtctggtac gttcctccgc tgtcaccgat
    24601 tcagtcctac gctgatgcgg gaggtttgcc gaaaagcgaa ggcgtgctgc ccgccatcga
    24661 aagcctgcgt attccggtgc aatatctcgc caatatgttg agtgccggtg ataccggtcc
    24721 ggtactgcgg gcgctgaaac ggatgatggc gatgcgccac tatatgcgtt cacaaaccgt
    24781 ggaaggcgtt actgatactc gtgccatcga cgaagtaggt ctgagcgtcg cccaggtcga
    24841 agagatgtat cgttacctcg ccattgccaa ctatgaagat cgtttcgtca tcccgacaag
    24901 ccatcgggaa atggcgggcg atgccttcgc agaacgcaac ggctgcggtt ttacctttgg
    24961 cgacggttgc cacggttcgg acagcaaatt caacctgttc aacagtagcc gtatcgatgc
    25021 catcaacatc accgaagtgc gcgacaaagc ggagggcgaa taatgcagat cctcaaagtg
    25081 ctcggcctgt tgatggagta cccagacgag ttgttgtggg agtgtaagga cgacgcgctg
    25141 gcgcttatcc gccgcgacgc gccgatgctc accgattttg cactcgacct gctcaacgcc
    25201 ccgctgctgg ataaacaggc cgaatggtgt gaagtgtttg accgcgggcg caccacgtcg
    25261 ctgctgctgt ttgaacatgt tcatgccgag tcccgcgatc gcggccaggc aatggtggac
    25321 ctgctggcgg agtatgaaaa ggtcggtctg caactgaatt gtagggaact gcccgattat
    25381 ctaccgctgt atctggagta tttaagcgta cttccggacg atcaggcgaa agaaggatta
    25441 ctcaacgttg cgccgatcct caccctgctt ggcggacgct taaaacaacg cgaggcaccg
    25501 tggtacgcgt tatttgacgc cctgttgcaa ctggcaggaa gccctctgtc aagtgacagt
    25561 gtcacaaaac agattcgcag tgaagagcgt gacgacaccc gccaggcgct ggatgcggtg
    25621 tgggaagaag aacaggtgaa gtttattgaa gataacgcca cggcgtgtga cagctcgccg
    25681 cttaatcaat atcagcgacg ctttagccag gatgtcgcgc cgcagtatgt cgacatcagt
    25741 gcgggaggtg ggaaatgatt cagtatctga acgtcttttt ttacgatatc tacccgtact
    25801 tgtgtggcac ggtttttatc cttggaagct ggctgcgcta cgactacggg cagtacacct
    25861 ggcgcgccgc ctccagccag atgctggata aacgcgggat ggtgctgtgg tcaaacttgt
    25921 tccatatcgg cattttgggg attttcttcg ggcacctgtt cggcatgtta acgccacact
    25981 ggatgtacgc gtggtttctg ccggtggcgg taaaacagca gatggcgatg atcctcggcg
    26041 gaatatgcgg ggtattgacg ctgattggcg gtgcggggct actggtgcgt cgtttaacaa
    26101 atccgcgtat cagggcgacg tcttctggtg cggatatcct gatcctcgcc attttgttaa
    26161 ttcagtgcat tctcgggtta accaccattc ctttttcagc acaacatccg gacggcagtg
    26221 aaatgatgaa gctggtgggc tgggcgcaaa gcattgtcac tttccagggc ggtgcatcta
    26281 cgcatcttga tggtgtcgcc tttatattcc gcgttcatct ggtgcttgga atgaccatct
    26341 tcctgctctt cccgttcacc cgactggtgc atgtctggag cgcgccgttt gagtacttta
    26401 ctcgtcggta tcagattgtg cgttcgcggc gttaattctc acgcgggccg gatagccctt
    26461 cgctctccgg ccacttgcag gctatgatag ttctccagcc acaggagaac gttaatgaaa
    26521 ccgcaagtgt accacgtcga tgcttttacc tctcaaccgt ttcgcggcaa ttctgccggt
    26581 gttgttttcc ccgccgataa tctcagtgaa gcgcaaatgc agcttatcgc ccgcgagtta
    26641 ggtcattcgg aaactgcttt tctgctgcac agcgacgaca gcgatgtgcg catccgctac
    26701 tttacgccaa cggttgaagt gccaatttgc ggtcacgcga cggtggctgc gcactatgta
    26761 cgttcaaagg tattaggttt gggaaattgc acggtctggc aaacgtcgct ggcaggaaaa
    26821 catcgtgtga ctatcgaaaa gcaaaatgat gattatcgta tttcgctgga acaaggtacg
    26881 ccaggctttg agccaccact gacaggtgaa acacgtgcag cgattatcaa cgcgcttcat
    26941 ctcactgagg acgatattct gccaggcttg ccaattcagg tggcaacaac aggacactca
    27001 aaagtgatga tcccgttgaa accagaagtg gatatcgacg ccctttcgcc tgatcttgct
    27061 gcgttgaccg ctatcagcaa acagattggc tgcaatggtt tcttcccgtt ccagatccgc
    27121 ccaggcaaaa gcgaaaccga cggtcgcatg ttctcgcctg cgattggtat tgtggaagat
    27181 ccggtgaccg ggaatgccaa tggtccgatg ggcgcatggt tagtacatca caacgtattg
    27241 ccccacgatg gcaacgtgtt gcgtgttaaa ggccatcagg ggcgcgcatt ggggcgtgat
    27301 ggtgtaattg atgtgacggt gacaattcgc gataaccaac cggagaaagt taccatttcc
    27361 ggcacggcgg tgattctatt ccatgctgaa tgggccattg atttttgatg ccgttgcctg
    27421 atgcgcttcg cttatcaggc ctacaaccgg actaatgtag gccggataag gcatttacgc
    27481 cacatccggc aacctgacat aaattatttt cccgcctccg ggtgcgtatc aaacgccgcc
    27541 atcaccagcg ctaactcatc cacagtaaag ccatgtttcg catcatctac gcccagacca
    27601 aactgttcct gcatcacggc atataacgac gccacatctg gtagatttcg ctgctcaact
    27661 gcgtgcccat tttcataatg ggtaaaatga aaattggtca gcgttagctt gccaccgtcc
    27721 ggcaaatggc gacacatcag caaatgatgg cgaaaatgcg actgcggcca gtgcgccgac
    27781 cagaaattgc ctatcacata atcgctttgt tgctgctcgc agagatcaaa acggtacatc
    27841 gactgccagt gctgatgatg attaaactgc aatacccaat catcaccctc ttgcaacaac
    27901 cgatactctc cgtgtggcgt ggtttgcatg atatccggca ttaaacgaat cggcgcggtt
    27961 agcgtctgcc caccgaaacc gacatcagca atccattttt ccccttccag ttccaccaac
    28021 agcaaacgat gggtgcgcgg cggtaatgct ggcggatttg ataacactac gcgacctaac
    28081 aagctgcgaa cgttaaaccc cagctcgcgt aacacccgct caaacacgcc attctgctca
    28141 aaacagtaac cgccacgacg ggctatcacc agtttctctt ccagcgattg atcatcaagc
    28201 tgtatttccc tcggcagcaa aacgtcgaga ttttcaaacg gaatggtgca attgtgtttc
    28261 aggtgcaatg cacgcagcgt atcaatattg gccgcagcag ctcccaacca gttaatacgg
    28321 gcaaaataat gattcagaat gggcgtcatc aggcgtttcc cttagtggtt ttctcaactt
    28381 ataacctgga atagacgccg cactggctat tttgtgcgat cgcggacatg catcacgttc
    28441 gcaaatcgcc aatcccgtta atttcgttac ttattgcgtt acgagctacg cttttaaaac
    28501 acccttcata gcgaggcgat atcgtgagcc aattcattcc cgtcgaatta caccatgcca
    28561 gctgtctgtt aaatcatggc ccaactgtca tgatcaccag tttcgatgag caatcccagc
    28621 ggcgtaacat tatggcagca gcctggtcga tgcccgtaga gtttgaaccg ccacgcgtgg
    28681 cgattgtggt agataaatcg acatggacca gggagttgat tgaaggtaac ggtaaatttg
    28741 gcatcgttat cccgggcgtt gcggcgacta actggacgtg ggcggtggga agtgtgtcgg
    28801 gtcgtgaaga agataagttt aattgctacg gcattccggt agtgagaggc ccggtgcttg
    28861 gtttgccgct ggtcgaggaa aaatgtctgg cgtggatgga gtgtcgcctg ctacctgcga
    28921 cttccgcgca agaaaaatac gatacgctat ttggcgaagt ggtatctgca gcggcagacg
    28981 cacgagtatt tgtcgaaggc cgctggcagt ttgatgatga taagctcaat acgttgcatc
    29041 atttaggtgc tggcatgttt gttaccagtg gtaagcgagt tacggcaggt taagcattac
    29101 atgctgtaac cgggtttctt tatcaaagcc tccatttggg gcgcgatttc ggccagggca
    29161 agattacgaa agcccgctcc ccgcaaggac tgacgcgaga tagtttctgt ccatggctgc
    29221 ttttcgcatc ttacgtctta accctgcctt gaatacctta tcattcgtta aaatattaat
    29281 agcgatgtgc cgtatccctg aaaataattc tgcggcgttt cctcttctta ttttgcagtc
    29341 gtcttcattc attaccacgt ccagacgcca gtgcagctta ttctccacgt gccagtggtt
    29401 tcggattgct gtggcgaact tctctgcggt taaatcagca gaactgatat aatatctgac
    29461 cgtcatttct ggctctttct tttgttctgc tattatggac cgaaaggaga ctgccacgca
    29521 taatttcttc agtcctttcc attcgaacgt gaaatcaata agttcatcag ggacatcgca
    29581 aacaatatga agacggattt cttctctgcc gtgactcttt tcactaatgg cgtaactgtc
    29641 atgttctgga ttatttaatt ctttcagtgg aaatttttcc tcaaaggctt tattaagccg
    29701 cccctgattt ccttttacag cgaataaata atcaccgccc tgtttttgta tcttctctgc
    29761 aatatctttc tggcaaccca tcgcatcagt tgtgatgatt tttcctttaa tatccagcat
    29821 gttaagaagt tcagggatag gtgtaatttc attggatttc tcatccgtcc tgatctgtcc
    29881 gatgaccaga ctgtgcattg ttgagaacgc actaatgaca tgaatcgctc ccttgcggcg
    29941 actcttgtca taagaatgcc ggagtgtttt tccatcaatt gcgatgacgt ctttatcatc
    30001 tgaagaatgg cagtcacgca tccagttaat aaagcactcg tgaaattttg caggactgat
    30061 acaggataca actctggcaa tggtatcgtg aacaggaata ccattatcaa aatcaccata
    30121 ttgcttcaaa aaatcgagat gtgtttcccc aaaatcctct atatcttccc agccttctgc
    30181 acccgaaata acggcacaaa tagtcaacag tagaatatcc gataatttat gttccacttt
    30241 ccaggcttgt ctgtaatcgg ggataataga aatatgttcc atcaattttt taagttccat
    30301 tttgttctcc ttaattatgt aaggagtatt tgatcatgta taagcaataa aaaacagctt
    30361 caggtaatga ggaatatctc aatttttaaa cataaaatgc gaattattta gtacaaaaaa
    30421 gcagcgttac gtgatctttc cctgatatct taatctgcac
//
LOCUS       DAFGPF010000056        30445 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFGPF010000056 DAFGPF010000000
VERSION     DAFGPF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30445
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.056"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1116)
                     /gene="ycjT"
                     /locus_tag="LSX49_002756"
     CDS             complement(<1..1116)
                     /gene="ycjT"
                     /locus_tag="LSX49_002756"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HBL7169147.1"
                     /translation="MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKGEINELVNLPDVVGMEIAINGEIFSLSREAWQRELNFASGELR
                     RNVVWRTSNGTGYTIASRRFVSADQLPLIALEITITPLDADASVLISTGIDATQTNHG
                     RQHIDEIQVRVFGQHLMQGIYTTQDGRSDVAISCCCKVSGDVQQCYTAKERRLLQHTC
                     AQLHAGETLTLQKLVWIDWRDDRQAALDEWGSASLRQLEMCAQQSYDQLLAASTENWR
                     QWWQKRRITVNGRDAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSDPTVARSLLRYRWHNLPGAQEKARRN"
     gene            complement(1113..2168)
                     /locus_tag="LSX49_002757"
     CDS             complement(1113..2168)
                     /locus_tag="LSX49_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL7169148.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALAEKYGNASLWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTAEQAREMCDTARKQGKVLAYDFHHRFAFDTQQLREQVTNGVLGEIYVTTARA
                     LRRSGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQREMADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(2178..2966)
                     /locus_tag="LSX49_002758"
     CDS             complement(2178..2966)
                     /locus_tag="LSX49_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL7169149.1"
                     /translation="MKIGTQNQAFFPGNILEKFRYIKEMGFDGFEIDGKLLVNNIEEV
                     KAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENDLKHVQIIGDFYHMNIEEDNLAQALHDHRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEAPAQAYRDSLAWLRTC"
     gene            complement(2984..4036)
                     /locus_tag="LSX49_002759"
     CDS             complement(2984..4036)
                     /locus_tag="LSX49_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBL7169150.1"
                     /translation="MKKLVATAPRVAALVEYEERAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFSPRPANAPRGIEFGKFQLGNMVVGDIIECGSDVNDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGADVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(4067..4909)
                     /locus_tag="LSX49_002760"
     CDS             complement(4067..4909)
                     /locus_tag="LSX49_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL7169151.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKSAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPVIFPFVDYFRNSMVVSVVSSVVAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(4896..5777)
                     /locus_tag="LSX49_002761"
     CDS             complement(4896..5777)
                     /locus_tag="LSX49_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL7169152.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     RLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(5798..7090)
                     /locus_tag="LSX49_002762"
     CDS             complement(5798..7090)
                     /locus_tag="LSX49_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7169153.1"
                     /translation="MIKSKIVLLSALVSCALISGCKEENKNNVSIEFMHSSVEQERQA
                     VISKLIARFEKENPGITVKQVPVEEDAYNTKVITLSRSGSLPEVIETSHDYAKVMDKE
                     QLIDRKAVATVISNVGEGAFYDGVLRIVRTEDGSAWTGVPVSAWIGGIWYRKDVLAKA
                     GLEEPKNWQQLLDVAQKLNDPANKKYGIALPTAESVLTEQSFSQFALSNQANVFNAEG
                     KITLDTPEMMQALTYYRNLAANTMPGSNDIMEVKDAFMNGTAPMAIYSTYILPAVIKE
                     GDPKNVGFVVPTEKNSAVYGMLTSLTITAGQKTEETEAAEKFVTFMEQADNIADWVMM
                     SPGAALPVNKAVVTTATWKDNDVIKALGELPNQLISELPNIQVFGAVGDKNFTRMGDV
                     TGSGVVSSMVHNVTVGKADLPGTLQASQKKLDELVEQR"
     gene            complement(7104..8783)
                     /gene="ycjM"
                     /locus_tag="LSX49_002763"
     CDS             complement(7104..8783)
                     /gene="ycjM"
                     /locus_tag="LSX49_002763"
                     /EC_number="2.4.1.352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosylglycerate phosphorylase"
                     /protein_id="HBL7169154.1"
                     /translation="MQQKITDYLDEIYGGTFTATHLQKLVTRLESAKRLITQRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYPQWLQRIFSHVHLLPFYPWSSDDGFSVID
                     YHQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQQPGFEDFFITVDP
                     KTDLSAVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LEKGAEYVRLDAVGFMWKEPGTNCIHLEKTHLIIKLLRSIIDNVAPGTVIITETNVPH
                     KDNIAYFGEGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPENEILALVEVLQQEGALVNWKNNPDGTRSPYEMNVTYMDALS
                     RRECSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLGYNRAINRKKY
                     SSKEITTELDNKATLRYSVYYKLSHLITLRRSHKEFHPDNNFTIDAINSFVMRIQRSN
                     ADGDCLTGLFNVSENIQHINITDLHGRDLISEVDILGNEITLHPWQVMWIK"
     gene            complement(8994..9308)
                     /gene="pspE"
                     /locus_tag="LSX49_002764"
     CDS             complement(8994..9308)
                     /gene="pspE"
                     /locus_tag="LSX49_002764"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HBL7169155.1"
                     /translation="MFKKGLLALTLVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(9383..9604)
                     /gene="pspD"
                     /locus_tag="LSX49_002765"
     CDS             complement(9383..9604)
                     /gene="pspD"
                     /locus_tag="LSX49_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HBL7169156.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(9613..9972)
                     /gene="pspC"
                     /locus_tag="LSX49_002766"
     CDS             complement(9613..9972)
                     /gene="pspC"
                     /locus_tag="LSX49_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HBL7169157.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(9972..10196)
                     /gene="pspB"
                     /locus_tag="LSX49_002767"
     CDS             complement(9972..10196)
                     /gene="pspB"
                     /locus_tag="LSX49_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HBL7169158.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(10250..10918)
                     /gene="pspA"
                     /locus_tag="LSX49_002768"
     CDS             complement(10250..10918)
                     /gene="pspA"
                     /locus_tag="LSX49_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HBL7169159.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREIEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLVRMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            11085..12062
                     /gene="pspF"
                     /locus_tag="LSX49_002769"
     CDS             11085..12062
                     /gene="pspF"
                     /locus_tag="LSX49_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HBL7169160.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEHFAIQMCREIKLPLFPGFTEHARETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPSEEAIAVSENTSLPTLP
                     LDLREFQMQQEKELLQVSLEQGKYNQKRAAELLGLTYHQFRALLKKHQL"
     gene            12216..12353
                     /locus_tag="LSX49_002770"
                     /pseudo
     CDS             12216..12353
                     /locus_tag="LSX49_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415812.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Putrescine importer PuuP"
     gene            12487..12732
                     /locus_tag="LSX49_002771"
     CDS             12487..12732
                     /locus_tag="LSX49_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HBL7169161.1"
                     /translation="MNHDIPLKYYDIADEYATECAEPVADAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            13045..14688
                     /gene="sapA"
                     /locus_tag="LSX49_002772"
     CDS             13045..14688
                     /gene="sapA"
                     /locus_tag="LSX49_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HBL7169162.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYAGKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQYIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKALGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            14685..15650
                     /gene="sapB"
                     /locus_tag="LSX49_002773"
     CDS             14685..15650
                     /gene="sapB"
                     /locus_tag="LSX49_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HBL7169163.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMIISAIRHMVLPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            15637..16527
                     /gene="sapC"
                     /locus_tag="LSX49_002774"
     CDS             15637..16527
                     /gene="sapC"
                     /locus_tag="LSX49_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HBL7169164.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            16527..17519
                     /gene="sapD"
                     /locus_tag="LSX49_002775"
     CDS             16527..17519
                     /gene="sapD"
                     /locus_tag="LSX49_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HBL7169165.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            17521..18327
                     /gene="sapF"
                     /locus_tag="LSX49_002776"
     CDS             17521..18327
                     /gene="sapF"
                     /locus_tag="LSX49_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HBL7169166.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            complement(18375..19538)
                     /locus_tag="LSX49_002777"
     CDS             complement(18375..19538)
                     /locus_tag="LSX49_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HBL7169167.1"
                     /translation="MARVSLSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTIT
                     QLTLTASLIGLGVGQLLFGPLSDKIGRKRPLILSLLLFIVSSILCATTNNIYWLVVWR
                     FIQGIAGAGGSVLSRSIARDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDW
                     RTLFWVMAEISTVLLLGCLLFIHETLPENKRGSSLLLTGRSVVQNRRFMRFCLIQSFM
                     LAGLFAYIGSSSFVLQKEFGFSPMQFSLVFGLNGTGLIIASWIFSRLARRINAMTLLR
                     GGLIAAILCALLTVLCAWIQLPIPALVALFFTIAFCSGIGTVGGAEAMSAVGTQESGT
                     ASALMGMSMFVFGGIAAPLSGIGGETLLKMSLAITVCYTLALLVALTRIDNQK"
     gene            complement(19547..20920)
                     /locus_tag="LSX49_002778"
     CDS             complement(19547..20920)
                     /locus_tag="LSX49_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBL7169168.1"
                     /translation="MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQGQGKAI
                     SHDWQQVIHDPRLQQVVTIALNSNRDVQKAIADIDSARALYGQTNASLFPTVNAALSS
                     TRSRSLANGTGTTAEADGTVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIA
                     EISTAWLTLAADNSNLALAKETMASAENSLKIIQRQQQVGTAAATDVSEAMSVYQQAR
                     ASVASYQTQVMQDKNALNLLAGTTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRP
                     DIQEAEHNLKSANADIGAARANFFPTISLTASAGVGSDALSSLFSHGMQIWSFAPSVT
                     LPLFTGGSNLAQLRYAEAQKRGLIATYEKTVQSAFKDVANALARRTTLEEQLDAQRQY
                     VKAEQQTVDVGLRRYQAGVGDYLTVLTAQRSLWSAQQELLALQLTDFTNRITLWQSLG
                     GGMSSLK"
     gene            complement(20924..24031)
                     /locus_tag="LSX49_002779"
     CDS             complement(20924..24031)
                     /locus_tag="LSX49_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HBL7169169.1"
                     /translation="MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTI
                     KISATYTGASAETLENSVTQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPD
                     TAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
                     SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAG
                     KIGALPSPDTQQLTATVRAQSRLQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDY
                     TAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFI
                     KISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSIN
                     TLTLFAMVLAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALVAIALVL
                     SAVFLPMAFFGGSTGVIYRQFSITIISAMLLSVVVALTLTPALCGSVLQHVPPHKKGF
                     FGAFNRFYRRTEDKYQRGVIYVLRRAARTMGLYVVLGGGMALMMWKLPGSFLPTEDQG
                     EIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAF
                     VSLKNWSQRKGAENTAQAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLA
                     NGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMPQLQVDIDSNKAVSLGLSLND
                     VTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSA
                     FATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSG
                     LSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVILVIPLGLLGAALAAWMR
                     DLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALRAAQTRLRPIIMT
                     SLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGK
                     PRRQE"
     gene            complement(24031..25152)
                     /locus_tag="LSX49_002780"
     CDS             complement(24031..25152)
                     /locus_tag="LSX49_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBL7169170.1"
                     /translation="MKYIATSVVAMLLLSGCDNTQSNNSSPSETEVGVVTLKSQPVSV
                     VSELTGRTSAALSAEVRPQVGGIIQKRLFKEGDLVKAGQPLYQIDAASYQAAWNEARA
                     ALQQAQALVKADCQKAQRYARLVKENGVSQQDADDAQSTCAQDKASVEAKKAALETAR
                     INLDWTTVTAPISGRIGISSVTPGALVTASQDTALTTIRGLDTMYVDLTRSSVDLLRL
                     RKQSLATNSDTMSVSLILEDGTTYSEKGRLELTEVAVDESTGSVTLRAIFPNPQQQLL
                     PGMFVRARVDEGVMENAILAPQQGVTRDAKGNATALVVNKDNKVEQRTLETGETYGDK
                     WLVLNGLHNGDRLIVEGSAKVTSGQTVKAVEVQANGGNA"
     gene            complement(25301..25867)
                     /locus_tag="LSX49_002781"
     CDS             complement(25301..25867)
                     /locus_tag="LSX49_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7169171.1"
                     /translation="MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLS
                     VGQIYRYFANKDAIIEEMVRRIIDFRIAQMDIDARTDHFPEVLALRKSLNEDDDALML
                     EVAAEATRNPRVMAMLEEADARMFANGCAHMKRMHPHLSDEHIRCCVEVFATMMEGTV
                     YRRLTPQKSDPQHLQEIYQDIVSMLINK"
     gene            26345..27133
                     /gene="fabI"
                     /locus_tag="LSX49_002782"
     CDS             26345..27133
                     /gene="fabI"
                     /locus_tag="LSX49_002782"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBL7169172.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDTSIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            27278..28405
                     /locus_tag="LSX49_002783"
     CDS             27278..28405
                     /locus_tag="LSX49_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707196.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HBL7169173.1"
                     /translation="MEQRHITGKSHWYHETQSSTAEYDVLPLVPEAAKVSDPFLLDVI
                     LDEETLAPFLSWLVPARVLAVELFPDPLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSSRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTVCDC
                     VIINQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESLRWRSSYEV
                     EKLPEEHTKSSTAELCQLANTLSLHPISLSLLEKLLNSTRVNTQPDNQLAALLCARIN
                     GSPACFAACMNSSNEYKKISPLLRKGENEINRWADRHSVERATVQAIQWLTRAPDRFS
                     AAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            28473..30407
                     /gene="rnb"
                     /locus_tag="LSX49_002784"
     CDS             28473..30407
                     /gene="rnb"
                     /locus_tag="LSX49_002784"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HBL7169174.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DGKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSTDGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETAYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
BASE COUNT         7327 a         8123 c         7507 g         7488 t
ORIGIN      
        1 gttgcgtcgc gctttctcct gcgcgccagg caagttgtgc cagcgataac gcagtaaact
       61 tcgggcaacc gtcggatcgc taaacagatg gaacggtagc aaaaatactt ctgtatccca
      121 gaaaacgtgg cctttgtagc cttcgccggt taaacctttc gccgcaatgc tgctgcgctc
      181 atcgtgggca ggcgtcatga tgcgcaggtg ataaagcgca taatctaatg cttgctgatc
      241 gtgcgcatcg cggccgttta ccgtgatacg acgtttctgc caccattgac gccagttttc
      301 tgttgatgct gcaagaagtt ggtcgtaact ctgctgcgcg cacatttcaa gctgacgaag
      361 cgacgcactg ccccattcgt ctaaagcggc ttgtctgtcg tcccgccagt cgatccacac
      421 cagtttttgc agcgtcagcg tctcacctgc gtgaagctgc gcgcaggtat gttgcaataa
      481 acggcgctct ttggcggtat agcattgctg cacatcaccg ctcaccttac agcaacagct
      541 gatggccaca tcactacgcc catcctgggt ggtgtagatc ccctgcatca gatgctgacc
      601 aaacacccgc acctggattt cgtcaatatg ctggcgaccg tggttggttt gcgtggcgtc
      661 aatgcctgtt gaaatcagca ctgacgcgtc ggcgtccagt ggagtaatag tgatttccag
      721 cgcaatgagc ggcagttggt ctgccgaaac aaagcgacgg ctggcgatgg tgtaaccagt
      781 gccgttgctg gtacgccaga caacgttgcg acgtaattcg ccactggcaa agttaagctc
      841 acgctgccat gcttcgcggg ataacgagaa aatctcacca tttatggcaa tctccatccc
      901 cacgacatca ggcaggttca ccagttcgtt gatttctcct ttacccgctc gatgatacag
      961 ccccgccaga tacatcccac gggtctggcg cgtgtaatct tcttcatggc tggcacgaag
     1021 cccaagatag ccgttcccct gcgccatcag cgaagcatac ttgttcaggg tatgctggct
     1081 gaaatggggt tctgataacg ttactggcct ggtcataatt ccacacgcgt ccctgtttcc
     1141 gcggattgat acaacgccgc caccagttgc tggatgatgt acccctgctc ggcgtcggct
     1201 atcatcacgg gcttgccctg tacgtgattg ataaaggctt ccatgctgcg caaatggcgg
     1261 ttgtcgtctg ccatttcccg ttgcatcagc gtcattaatt caccgttgtt atcggtgtag
     1321 atatgtgccg gaaacagcgt cgcaccggct ttatcaccac aaaagctgac attcataatc
     1381 gactgttcgc ggatgttgag tgcaaatgac gtttccagcc acagaatgcc gccgttatga
     1441 aattcaatgg tgccaaacag cgaatcttca acgctgtaag ttgccgggtc ccactcgcca
     1501 aattgaccac agctcttttg cgtgccgatc ttttgaaagc tatgcgcatt cacgcttttc
     1561 accgccggaa agcccagcac atacatcgca gcatccagca tatgaatgcc gatgtcgatc
     1621 agcgggccac caccctgcag ttctttattg gtaaagacac cccagccggg aacgccgctg
     1681 cgacgcaggg cgcgggcggt ggtaacgtaa atctctccca aaacgccgtt ggtcacctgt
     1741 tcacgcagct gttgcgtatc gaacgcaaaa cgatggtgaa agtcgtaggc cagcaccttg
     1801 ccctgtttgc gcgcggtatc gcacatttcc cgcgcctgtt ctgccgtcat ggcgggcggt
     1861 ttttcgcaca tcacatggca gcccgcttca agcgccatca gggtatgttc gtaatgaaaa
     1921 cggttcggtg agcagacgct aaccacatca ggtttcaccg ccagcagcat ggcctgcgga
     1981 tcgtcccaca aggatgcatt accgtatttt tctgccagcg cctgcgcctg ggaaaggcgg
     2041 ctgtcacaga cggccaccag ttccagatcg ttgcgggtgc agtagtacga agcatgaacc
     2101 ttatccgcca cctggcctgc gccgattatc gcgacacgca gcggagagct tgtcattgca
     2161 cttttcacaa agacctctta gcaggtgcgc aaccaggcca acgaatcacg gtacgcctgg
     2221 gcaggagctt ctgcccggat acgcccttca tacaccacat aaccctgata gttatcggcg
     2281 cgcagctgtt caaacagcgc gtggaaatcg agggtgccgc tgcccggctg gtaacgatgg
     2341 ttatcggcaa tatgcacatg accgagcaag tcgcggtggt catgcagcgc ctgcgccagg
     2401 ttatcttctt cgatgttcat gtgatagaaa tcgccgataa tctgcacatg tttaagatcg
     2461 ttttcgacga tgtaacggcg ggcatcggcg agagtattga tcatatgatc ctgataacgg
     2521 tttaacggtt cgagatacac cacggttccg gtacgcgcgg cgacctgttc cagtacgcgc
     2581 agggaatcac tcaccatttt gcggtcgccg tccaggctgc gcggcgaggt catcggcggt
     2641 aaacggaagg taaacatgcc ccatgcagca ggaacgacga tacctttacc gcccacttct
     2701 gccagcgctt cgagaatgcg ttcgatctgc tttaagccat taagacgacg ctcttcgata
     2761 aaatcaccaa tccagccgtc atagccgccg caggcagtgg tcaccggtaa accggtttct
     2821 ttgatcgccg ctttgacttc ttcgatgttg ttgaccagca gtttgccgtc aatctcaaaa
     2881 ccatcgaagc ccatctcttt gatgtaacga aatttctcca gaatatttcc cggaaagaat
     2941 gcctgattct gtgtgcctat tttcattttt tcattccttt gaattaaaac gtaacgccca
     3001 ttttgatgct ctgttccgga tgctgatcga catactgcat gtagctttcc gggctgttgg
     3061 caaaggtcac taccgggtcg attaaatctt cgcaattgag ataaccgttc atcagcagtt
     3121 cccagcaggt ttcttcaata cgcttacggc tccagcgcgg ataatccggg ttcggttcgc
     3181 tgcacgcgcg ggagaaaaca attttggcgt tattgaaatg cgcttcgcgt ccgaggttaa
     3241 aaccttcagc aaatggtttg gcaaacgcga cataggagat ggtgccgccg taggccagac
     3301 cgcggagcgc cgactgcagc gcgtcggcgt agccgctggt ttcgataatc acatcggcac
     3361 cctgcttgcc ggtcagcgtt ttgatctctt tacctacgtc agcgccaatg gggttaagac
     3421 agaaatccgc accgtggcga cgggcaatat cacagcgatg agcgatagga tcgacaccaa
     3481 tcaccaccga cgcgccagcg cgttttgcca gttgaatggc aatttgacca atcgcgccaa
     3541 gccctaccac caccacaaaa tcgcccacgc gcacgttggc atcgcgcacg ccgctcatgg
     3601 caaactgcgc cgggtcgtaa cagacggcgt ttttccagga gctgccttgc ggcattttgc
     3661 gcagcttgta gttattcact gcgttaatga tgaccgtctc ggagagcggg ccgtagccgc
     3721 atacgctgtc gcccaccgcg tagtcgttaa cgtcgctgcc gcactcgata atgtcgccaa
     3781 ccaccatgtt gccaagctgg aacttgccaa actcaatgcc gcgcggcgca tttgccggac
     3841 gcgggctgaa catctgccat tcaccgttaa agtcttcatc gataaacgga ctggcagcgc
     3901 ggaaatcgac cacttccgtc ccgtgcttcg gagcgccgaa acgcacgcgg atcttcactt
     3961 cattggctaa aatcgcccgc tcttcatact caaccagcgc agctacacgc ggtgctgtgg
     4021 ctactaactt tttcatgtaa aactccttgt aaagaaattg gtcgctttag cccttcacgc
     4081 caccagcggt caaaccactc ttaataaaac gttccgaaag cgcatacata atcactaccg
     4141 gtagtgcggt caccagcgag gccgccatca tccgtcccca gatgtaatca ggcgtactga
     4201 acagcgcgtt caggcccaca ggtaaggtga aattgctggc gctggaaagg aaaatcgacg
     4261 caaacagata gtcgttccac gccaccataa agcagtagac gaatacggat atcagcccgg
     4321 acattgccag gggcacggtg atacggaaga taatttgcag acgattgagg ccatccatca
     4381 ttgccgcttc ttcgatttca tcggggatgg tgtcgaagta gcttttcagc ataaacacgg
     4441 cggtaggcag agtttgcgtc accatggtga taatcagcgc catctcggtg tcgtaaatgc
     4501 caagtgcggt gatgattttg aacagcggca ccaccagcaa aatgccggag aacatgtaca
     4561 ccgtgtaaaa gctggcgttg atggtcattc gccctttaaa gcgcaggcgg gaaagcgcgt
     4621 aagccccaag aatgccgaga aataccgcca ccacggatga aaccaccgac accaccatgc
     4681 tgttacggaa gtagtcgaca aacgggaaaa tcaccggatt aaaaatgtcg acgtaatgct
     4741 ccagcgtcca ctgctgtggc agcaacgtag gatgcagcga gatcgcctct tttgcgctct
     4801 tgaacgaggt catcagcatc acaaaaaatg gaaacagcgt gatgatgaga aacagcgcca
     4861 gcccgcagta aaaaccgatt cgactgagtg tgcgtttatt tgttgccatt gaggttcacc
     4921 cgtttcctgg tcagcagaat gacagcgaaa ataatgatga aaagcaccac cgagatcgcc
     4981 gccgctttcc ctaagtcatt aaaggcaaag gcggttttgt agagatagac accgagaata
     5041 tcgaccttgg tcgtcagcag ataaacatcc gcgaacatgt agaacatcca gatagtgcgc
     5101 agggtcacca ccgtcgccag aaccggcata atcgcgggca gcgtgacgat gcgaaaccgt
     5161 tgccaggcat tcgcgccatc catctctgcc gcttcgtaca gcgatttgtc gatggtctgc
     5221 aaaatcgcca gaaacgagat aaaggcatac gggaagtagc gccagatggc gaacagcacc
     5281 accagcacaa aactactgcc cgggttatcg aaccacagcg gcgcctgctc atagagatgc
     5341 agaagatcga cgccgaggta gttcacaatg ccgtagccgt tgttgaacat gtatttccag
     5401 gcgaacacca gcgaaataga cggcgttacg taggaaagga tcaccagcga acgcgcggtt
     5461 ttgcgcaggc ggaactcgcg gttgaaaaac atcgccacgg ccagcccgag cacggtgctg
     5521 cccgccacca caagcgcggt ataccagacc gtcatccaca gcgagtgcca gaaaccagga
     5581 tcggagagaa tgcgcacata gttactcacc ccaacaaacg ttgactcgat gttgggatta
     5641 agcggcagac gtaaaaaact gatttcgata ttcgacacca tcggccacgc caccagaccg
     5701 cccagcagta ataagctggg cgcgagaagc aacagcgcaa agggcatatc ggaacgacct
     5761 gaaaaaagcc tgttcattgc ggattcctgt cctgggttta gcgctgttcg accaactcat
     5821 ccagcttttt ctggctcgct tgcagcgtgc cagggaggtc ggctttaccc acggtgacgt
     5881 tatgcaccat tgaactcacc acaccagacc ccgtcacatc acccatgcgg gtaaagtttt
     5941 tatcccctac tgcgccaaag acctgaatat ttggcaattc gctgattagc tgattcggca
     6001 attctcccag cgccttaata acgtcgttgt ctttccaggt ggcggtagtg acaaccgctt
     6061 tgttcaccgg cagcgccgcg cctggtgaca tcatcaccca gtcggcaatg ttgtccgcct
     6121 gctccataaa ggtgacaaat ttttcagccg cttcggtctc ttcagtcttt tgcccggcgg
     6181 taatggtcag cgaggtcaac atgccgtaga ccgcagaatt tttctcggtt ggcaccacga
     6241 aaccaacgtt tttcggatcg ccttctttaa tcacagccgg aaggatatag gtggagtaaa
     6301 tcgccatcgg cgcggtgccg ttcataaaag cgtctttcac ttccatgatg tcgttagaac
     6361 ctggcatggt gttggcagca aggttgcggt aataggtcag cgcctgcatc atctctggtg
     6421 tatcaagggt gattttgcct tcggcgttaa agacgttagc ctgattggat aacgcaaact
     6481 gggagaaaga ctgttccgtc aacacgcttt ctgctgtagg cagcgcaata ccgtattttt
     6541 tattcgccgg gtcattcagt ttctgtgcaa cgtccagcaa ttgctgccag ttttttggct
     6601 cctccagccc agcttttgcc agcacatctt tgcgatacca gatcccgcca atccatgcgc
     6661 tgacaggaac accggtccag gcgctgccat cttcggtgcg cacaatccgc agtacgccat
     6721 cgtagaacgc gccttcaccg acgttgctga tgaccgtggc aaccgcttta cgatcgataa
     6781 gctgctcttt gtccatcact ttggcgtagt catggctggt ttcgatcact tccggcagcg
     6841 aaccgctacg tgaaagggta atgactttgg tgttataggc gtcttcttcc acgggcactt
     6901 gttttacggt gatacctggg ttttcttttt caaaacgggc aatcaatttg ctgatgacgg
     6961 cctggcgctc ctgctccacc gaagaatgca taaattcgat ggatacatta tttttatttt
     7021 cttctttaca gcctgaaatc agggcgcagg aaaccagtgc tgataacagc acgatttttg
     7081 atttaatcat gaaatgttcc tttttattta atccacataa cctgccaggg atgcagtgtt
     7141 atttcattac ccaatatatc aacttcacta atcagatccc gaccgtgcag gtcagtaata
     7201 tttatatgct gaatattttc gctgacatta aacaatcccg tcaggcaatc gccatccgca
     7261 ttgcttcttt gaattcgcat tacaaatgaa ttaattgcat cgatggtgaa attattatcc
     7321 ggatgaaact ctttatgact gcgacgaagg gtaattaaat gcgacaactt ataatatacc
     7381 gaatacctta atgtcgcttt attgtccagt tctgtcgtta tctctttact agagtatttt
     7441 ttacggttaa tcgcgcgatt atatccaagt ttttcgacac cggcgtaatc attacgcgac
     7501 cccagaatgc tttgaatata tatcgctggc acaccgggga aacttaacaa aatcgcatgg
     7561 gcgagaataa acctggcaca ccgttcttcg tcgctacact cacggcggct caacgcatcc
     7621 atataggtga cattcatttc ataggggcta cgcgtaccgt cgggattatt tttccagttt
     7681 actaatgccc cttcctgctg taacacctcg accagcgcta atatttcgtt ttcgggtaac
     7741 aacccccgca gtgggttaag cccgatgcca tcgtgagagg caaggaagtt aaaccaggtg
     7801 gtgttgctgg aaggtagtgt caggttttgc gcccacgcac aaagtgcctc aacgttctgt
     7861 ttttgcaccg catgcagcac cagcggcggc agcgagaact ggtacaccat atgcgcttcg
     7921 tcatcgcctt cgccaaagta agcaatgttg tctttatgcg gaacattggt ctcggtaatg
     7981 atcactgtgc ctggcgcgac gttatcaata atcgaacgta acagtttgat aatcagatgt
     8041 gttttttcca gatggatgca gtttgttccc ggctctttcc acataaagcc aacggcatcc
     8101 agacggacat actctgcgcc cttttccagg tagcacagca atacatccac catcgccagc
     8161 aacacttcag ggctacggta attgaggtca atttgatcgt cgctaaaggt ggtccataaa
     8221 tgacgcgttg aatgatcgcg catctggaat ggcgttaata acggtaacgc acgcgggcga
     8281 gtgacggcgc tgagatcggt tttcggatca acggtaataa aaaaatcttc aaaacctggc
     8341 tgctgttgta aatagttttt aaaccattca ctttttgccg acatatggtt gcagacaaaa
     8401 tcaaacatta aatggctgca ttcaccgagt tgctgaatat cctgccactc ccccgcttca
     8461 ctggcgacct gatgataatc aattaccgaa aatccatcat cagatgacca tggataaaaa
     8521 ggtaataaat gaacatgtga aaaaattctt tgcagccatt gagggtaaaa ctgattaaat
     8581 gtgggtagtg gctttaaatc attactgtga aattgatcgg cataggtaat taacacgaca
     8641 tcactttcat cccagtgttt tttacgtcgc tgtgtaatta atcgtttcgc actctcaaga
     8701 cgcgttacaa gtttctgtaa atgagtcgcg gtaaatgttc caccgtagat ttcgtccagg
     8761 taatccgtaa ttttctgttg catgttgcct ttccgtggta gcggtcccat gaagcgagag
     8821 actactccgc ataaaataaa ctgtcaattg agctcaaggg gtttagtcac gcaggaaatc
     8881 tttttttacc tgggaaaaag cgtatttgtg agctgacgca aataatctat ggggatgtaa
     8941 ataaggtgtg acagaaaaaa acggcgcata agcgccgctc atggtgaatt cttttaacct
     9001 ttgaccttcg gcattgcgat gtctttcagg ccaccggcgt tctcaacgtg ggtatatccc
     9061 atctcgctaa ggatctcttt tgcctgccct gactggcgtc cggcattgca atacactttc
     9121 acggtgtcgt ttttatccgg aacggcggta gcaatgcgct ctttcacttc cttcagggga
     9181 atattgatgg ccccctgaac gtgctcttgc tgatactgct ctggaacacg aacatcgatc
     9241 cagtgttcag cggcgaaaac gggcagtgaa aacaccagtg tcagagcaag taagcctttt
     9301 ttaaacatgt aagcgtcctt ctatggatga aaattgctat ccattatacg cctgagattt
     9361 aaccattttt gcgaaactcc cctcaccttt tataacgctg cgccagttta ttggcagccc
     9421 gacttaacag cggttccagc gccacagcca gcaacatttt cagcggtcgg cgagcaactg
     9481 attttatcgc ccagcccgcc acacccgccg ggccatagcg cagtgcggta agaagtacca
     9541 gcttgcctgc taatttgaac ccaggcttca ccttttgccc ggcctgttgc cagcgagtat
     9601 tcataacttt cctcacagtt gacggaaacg gctacgcagc gtgaaagtgt cggaagtgac
     9661 ataacgttcc atctcgcgta aacgcgtttc acttgccgcc agttcacggt cgacttcatc
     9721 cagcaattcg ctgctggaag gtagctgctc accaaaggcc atgttgtccg gcattggatc
     9781 aagcgcaaat gacaaaatga tgtaagcaac cagggtaaac agcgccagac cgaagaaaat
     9841 cgacagcacc accaggatac gcaccagttt tactggtaca tcaaaatagt tggcaatccc
     9901 ggcgcagacg ccacggacca tgccctgctg cggaatacgc cataattttt tattgagatt
     9961 aatgcccgcc attagcgatc cctccagttc ggatgttctg catcaagaat ggattccagc
    10021 gcctgaatac gctcgcgcat ccgttttgct tcatcagcca gttgcgctaa tcgctgctgc
    10081 tcactttgtg acaattcact gcgaccggaa cgattgctgt aatgcagcca taaccagatc
    10141 ggtaaaacaa acagcacaaa aatggttaac ggaatagcca gaaatagcgc gctcataagt
    10201 actccttaga cgatgagcgg cggcgcgttc ggacgccgcc tggatgttat tattgattgt
    10261 cttgcttcat tttggctttt aattgtgcca gttgctcgct gattgcatca tcggctttca
    10321 gttcggcaaa ctgatcgtcc agcgattttt gtttaccgaa gctgtggctt tctgcttccg
    10381 cttccatctg gtcgatacgg cgttcgaaag attcgaaacg agccattgct tcatccagtt
    10441 tgccactgtc cagctgacga cgcacatcgc gcgacgagtt tgccgcttga tggcgtaaca
    10501 tcaatgcctg ctggcgagcg cgtgtttcgc tcaatttgtt ttccagctcg ccgatctctt
    10561 tcttcatacg cactagcgta tcgtccacca gcgtcacttc atgttccagg ctcttaatca
    10621 gatcggtcag tttctgtttt tcaattaacg ccgcacgcgc cagatcctct ctctctttca
    10681 gcagtgccag ttccgctttt tcctgccatt caatttcacg agccgacgct tgttcaatac
    10741 ggcgagtcag ctgtttcttt tctgccagcg cacgcgccga agtagaacgt acttcaacca
    10801 atgtatcttc catctcctgg atcatcagac gcaccagttt ctgtggatct tccgctttct
    10861 ctaacagagc gttgatgttg gcattcacga tgtcggcaaa gcgagaaaaa atacccataa
    10921 tgttgtcctc ttgatttctg cgttcaggat tgtcctgctg aactgttaat acaatttgcg
    10981 tgccaatttt ttatcttttt gatttataaa gatctgattg aagaatcaac agcaacatgc
    11041 caggatgaat tagcgaatta cactaacaag tggcgaattt catcatggca gaatacaaag
    11101 ataatttact cggtgaggcg aacagctttc tcgaagtgct ggaacaggtt tcgcatctcg
    11161 caccgctgga caaaccggtg ctcatcatcg gcgagcgcgg caccggtaaa gagctgattg
    11221 ccagccgtct gcattatctc tcctcccgtt ggcaagggcc gtttatttcc cttaactgcg
    11281 cggcgttaaa tgaaaatttg ctggattccg aactgtttgg tcacgaagcg ggggcgttta
    11341 ccggtgcgca aaaacgtcat ccagggagat ttgaacgtgc cgacggcggt acgctatttc
    11401 ttgatgaact cgctacggca ccgatgatgg tgcaggaaaa attattgcgt gtgattgagt
    11461 acggtgaact ggagcgcgtc ggcggcagcc agccattgca ggtgaatgtg cggttggtat
    11521 gcgcgacgaa tgccgatctc ccggcaatgg tcaatgaagg gacttttcgc gctgacctgc
    11581 tcgaccgact agcgttcgat gttgtgcaac tgccgccact acgcgaacgt gaaagcgaca
    11641 ttatgttgat ggcagaacac tttgccatcc agatgtgtcg ggaaatcaag ctgcctctgt
    11701 tcccgggttt taccgagcac gccagagaaa cattgctgaa ttatcgctgg ccgggaaata
    11761 tacgtgaatt gaaaaacgtg gtggaacgtt cagtgtatcg ccacggcacc agcgattatc
    11821 cgcttgatga catcattatt gatcccttta aacgccgtcc atctgaagaa gccatcgccg
    11881 tttcagaaaa cacctcgctt ccgacgctgc cgctggattt acgcgagttt cagatgcagc
    11941 aggaaaaaga actgcttcag gtcagcttgg aacaagggaa gtataaccag aagcgcgccg
    12001 ctgaattgct ggggttaacc tatcatcagt tccgcgcgtt gctgaaaaag caccagcttt
    12061 agcatttcga caatgcaact tgccgggtgt gccgtgaacg ccttatcagg cctacaaaat
    12121 caatacgtcg tttgcaggcc tgataagcgc tgcgcatcag gcattattgc gttaaccctg
    12181 cttctgcgta ttaatctctc agcgcatcct gcaaaatttt cattgccgca tcgaattgcg
    12241 caaccgggat ggtatgggct tcgttaggcg gcgcatattt gtggtatttg atccgccgct
    12301 atcgcaaagt gccattgtat gatggcgaca gaacgccggt gagcgaaacg taatagtcga
    12361 atgcgcggcg cattatcctg cctgagggta atgcaccgcg ccattaacta taaaaatatg
    12421 tatgacccgg atcacgagtg ctatcatccg cccttatgct tagcgcatta accccagggg
    12481 caaataatga accacgatat cccgctaaaa tattatgata ttgccgatga gtacgcgacc
    12541 gaatgcgcag agcctgtcgc agacgctgaa cgcacaccgc tggcccacta cttccagtta
    12601 ctgctcaccc gtttgatgaa caatgaagag atcagtgaag aagcccaaca tgaaatggct
    12661 gctgaagcgg ggattaatcc cgtacgcatt gatgagatcg cagagttttt gaatcaatgg
    12721 ggtaatgagt aattatttaa ttgcagacta tcggtcagta tcgttgcccg gataaagcgt
    12781 tcgcgccgca tccggctaaa aatgacacgc actgcagcgt gctttaatgg gtttctcacg
    12841 atcgtaccgc tctgctcctc gctaagttgt tctgtgagtt atagttataa agaaatcacg
    12901 ggtacgaatg ttgaactgat ggcgacgcca cctgttcaat gaccaaccac acggccctca
    12961 ttattacctc tgaacacaaa cggtaatggc aaatgtcatt aaatattagt aagatagcct
    13021 ctttacataa aatcccttaa tattatgcgc caggtattat cgtctctttt ggtgattgct
    13081 ggacttgtga gtggtcaggc aatcgccgcg cctgaatccc ccccgcatgc tgatatccgc
    13141 gacagcggtt ttgtctattg cgtcagcggg caagtcaaca cctttaaccc atccaaagcg
    13201 agcagtgggt taattgtcga tacccttgcc gcccagtttt atgatcgact gctggatgtc
    13261 gatccctata cctatcgtct gatgccggaa cttgccgaaa gctgggaagt actcgacaac
    13321 ggcgcaacct atcgcttcca cctgcgtcgc gatgttccgt ttcaaaaaac cgactggttt
    13381 actcccactc gtaaaatgaa tgccgacgat gtggttttta ccttccagcg aatttttgac
    13441 cgcaacaacc cgtggcataa cgttaatggc agcaacttcc cctacttcga cagcctgcaa
    13501 tttgccgata acgtgaaaag cgtccgcaaa ctggataatc ataccgttga gttccgtctg
    13561 gctcagccgg atgcttcttt tttgtggcac ctcgcgaccc attatgcttc ggtcatgtcg
    13621 gcagaatatg cagggaagtt agagaaagaa gatcgccagg agcaactcga ccgtcaaccg
    13681 gtcggcaccg gtccgtatca gttgtcggaa taccgcgccg ggcaatatat tcgcttacaa
    13741 cgtcatgatg atttctggcg tggtaagccg ttgatgccac aagtggtggt ggatttaggc
    13801 tctggcggta caggacgatt gtcgaaactc ctgaccgggg agtgcgacgt tctggcctgg
    13861 cctgctgcca gtcagctatc cattttgcgt gacgacccac gcttgcgttt aacgctgcgt
    13921 cctgggatga acgtcgccta tctggcattc aacaccgcca aaccgccgct aaataatccc
    13981 gctgtccgcc atgcgctggc actggcaatt aataaccagc gcctgatgca atccatctat
    14041 tatggtacgg ctgaaacagc ggcctctatt ttaccgcgcg cctcgtgggc ctatgacaac
    14101 gaggctaaaa ttactgaata caatccggca aaatcgcgcg aacagttgaa ggcgttgggg
    14161 ctggaaaact taacgctgaa actgtgggtg cccacacgtt cgcaggcgtg gaaccccagt
    14221 ccactgaaaa ccgccgaact gattcaggcg gatatggcac aggttggcgt aaaagtggtg
    14281 attgtgccgg tagaaggtcg ttttcaggag gcgcggttga tggatatgag ccatgatctg
    14341 acgttatccg gttgggcgac ggacagtaac gacccggaca gtttcttccg tccgttactg
    14401 agctgcgcgg caattcattc gcagaccaac ctcgcccact ggtgcgatcc gaaattcgac
    14461 agcgtgttgc gtaaggcgct ctcctcgcag cagctggcgg cgcgtattga agcctatgac
    14521 gaagcgcaaa gtattctggc gcaggaatta cctattctgc cgctggcgtc gtcattgcgt
    14581 ttgcaggcct atcggtacga tatcaaaggt ctggtactta gcccgtttgg taacgcctcc
    14641 tttgctgggg tgtatcgcga gaaacaggat gaggtgaaaa agccatgatt atcttcacct
    14701 tacgccgtat tttgttattg attgtgacct tgttcctgct gaccttcgtt ggcttcagct
    14761 tgagctattt caccccacat gcgccgttac aaggcgcgtc actgtggaat gcctgggtgt
    14821 tctggtttaa tggcctgatc cactgggatt ttggtgtttc cagcattaac ggtcaaccga
    14881 ttgccgaaca gttaaaagag gtcttcccgg caacgatgga actgtgcatc ctcgccttcg
    14941 gttttgcgct gattgttggc atccccgtgg ggatgattgc cgggattacg cgccataagt
    15001 ggcaggataa cttgatcaac gccatcgcct tactgggctt ttcaatcccg gtgttctggc
    15061 tggcgcttct gttgacgctg ttttgttcac tcacgctagg ttggttgccc gtttcagggc
    15121 gtttcgatct gctctacgaa gtgaaaccga ttaccggttt tgcgttgatt gatgcctggc
    15181 tttcggactc accgtggcgg gatgaaatga tcattagcgc aatccgccat atggtattgc
    15241 ccgtgatcac cctgtcggtt gcgccaacaa ctgaagtgat ccgactgatg cgtatcagca
    15301 ctatcgaagt gtatgaccag aactatgtta aagcagcggc gacccgcggt ttgtcgcgct
    15361 ttactatttt gcgtcgccac gttctgcata acgcgttacc tccggttatt cctcgcctgg
    15421 gcttacagtt ttccaccatg ctgacgctgg cgatgatcac cgaaatggtt tttagctggc
    15481 cgggtttagg gcgctggtta attaacgcca tccgccagca ggattacgca gccatttccg
    15541 ccggagtgat ggtgtgtggc tcactggtca ttattgttaa cgtgatttct gatattttgg
    15601 gtgccatggc taaccctctg aaacataagg aatggtatgc cttacgatag cgtatacagc
    15661 gaaaagcgcc cgccgggcac gctgcgtacc gcctggcgca aattttatag tgacgcctct
    15721 gcgatggtcg gcctgtacgg ctgcgcgggg ctggctgtac tgtgtatttt tggcggctgg
    15781 tttgcgcctt acggcatcga ccagcaattt ctcggttatc aattattgcc gccgtcatgg
    15841 tcgcgctatg gcgaagtttc tttcttcctg gggactgacg acctcggacg cgatgtttta
    15901 agccgtttac tgagcggagc tgcgccaacc gtaggtggcg catttgtggt gacgcttgcc
    15961 gcgacgatct gtggcctggt actgggcacc ttcgccgggg cgacccacgg cctacgctca
    16021 gcggtgctta accatattct ggatacctta ctggcgatcc cttcgctgct gctggcaatt
    16081 atcgttgtag cgtttgccgg accgagtttg tctcacgcca tgtttgctgt ctggctggcg
    16141 ctgctgccac gtatggtacg ttcgatttac agcatggtgc atgacgaact ggaaaaagag
    16201 tacgttatcg ccgcccgtct ggatggcgca tcaacgctga atattctctg gtttgctgtg
    16261 atgcccaaca tcaccgccgg gctggtcacc gagatcaccc gcgcactgtc gatggcaatt
    16321 ctcgatatcg ccgcgctggg ctttctcgat ctcggcgcac aactgccctc gcctgaatgg
    16381 ggagcgatgc tcggtgatgc gctggaactg atttatgtcg ccccgtggac tgtcatgctg
    16441 cctggtgcgg cgattatgat tagcgtgctg ttggttaacc tccttggcga cggtgtccgt
    16501 cgtgcaatta ttgcgggggt ggaataatgc cattactcga tattcgtaac ctgaccattg
    16561 aatttaaaac cggtgatgag tgggttaaag ccgtcgaccg cgtaagtatg accttaaccg
    16621 aaggtgaaat ccgcggtctt gttggcgaat ccggttccgg taaaagtttg attgcgaaag
    16681 cgatttgtgg ggtgaataaa gataactggc gtgttactgc tgaccgtatg cgttttgatg
    16741 atatcgattt gctgcgtctc tccgcacgcg aacggcgcaa gctggttggt cacaacgtgt
    16801 cgatgatttt ccaggaaccg cagtcgtgtc ttgacccttc agaacgtgtg ggtcgccagt
    16861 tgatgcaaaa catcccagcc tggacctata aaggccgttg gtggcagcgt tttggctggc
    16921 gcaaacgccg tgccattgaa ctgctgcacc gcgtggggat taaagatcac aaagatgcga
    16981 tgcgcagttt tccctatgag ttgaccgaag gcgaatgtca gaaagtgatg atagccattg
    17041 cactggcgaa tcaaccgcgt ctgctgattg ctgacgaacc gacaaactca atggagccaa
    17101 caacccaggc gcaaatcttt cgcctcctga cgcgtctcaa ccaaaacagc aataccacta
    17161 ttttgcttat cagccatgac ttacaaatgc ttagccaatg ggcggataaa attaacgtgc
    17221 tttactgcgg tcaaacggtg gaaaccgcgc cgagtaagga gttggtgacg atgccacacc
    17281 atccttatac ccaggcgctg atccgcgcga taccagactt cggcagcgcg atgccgcata
    17341 aaagtcgcct caatacgctg cccggcgcta tcccgctact ggaacagtta ccgattggtt
    17401 gtcgtctggg gccacgttgc ccgtatgcac aacgagaatg cattgtgacg ccacgtttga
    17461 cgggggcgaa aaatcatctc tatgcctgtc atttcccact gaacatggag aaagagtgag
    17521 atgatcgaaa cgctacttga agtgcgtaat ttaagtaaaa cgttccgcta ccggaccggc
    17581 tggtttcgtc gtcagaccgt agaagcggta aaacccttga gctttacgct acgtgaaggc
    17641 cagacactgg cgattatcgg cgagaatggt tcgggtaaat ccacgctggc aaaaatgctg
    17701 gcgggaatga tagaacctac cagcggcgag ttattgattg acgatcatcc gctgcatttt
    17761 ggcgattatt ccttccgcag tcagcgtatt cgcatgattt ttcaggatcc ttccacctcg
    17821 ttgaatcccc gtcaacgtat ctcgcaaatt ctggattttc cactgcgcct gaacaccgac
    17881 ctggaaccgg aacagcgtcg caaacagatt attgaaacga tgcgtatggt tgggctgcta
    17941 ccggatcacg tcagttacta tccgcatatg ttggcacccg ggcaaaaaca gcgtctgggt
    18001 ctggcgcgcg cgctgatatt gcgcccaaaa gtcattattg ccgatgaagc cctcgcctca
    18061 ctggatatgt cgatgcgttc gcagttgatt aatctgatgc tggagttaca ggaaaaacag
    18121 ggcatttcgt atatttatgt tacccagcat atcggaatga tgaagcacat tagcgaccag
    18181 gtgctggtga tgcatcaggg cgaggttgtc gagcgaggca gcaccgcaga tgtgctggca
    18241 tcgccgctgc atgaactcac caaacggctg atcgccggtc attttggcga ggcattgacg
    18301 gcggatgcgt ggcgtaagga ccgttagtgt tttgcacctc atcctgacag gcccccctca
    18361 ggatgaggtg ttcattactt ttggttgtcg attctggtga gagcaaccag caatgccagc
    18421 gtataacaca ccgtaattgc cagactcatt tttaacagtg tttctccgcc aattcccgac
    18481 aatggcgcgg ctataccgcc gaagacaaac atgctcatcc ccatcaacgc agacgccgtt
    18541 ccagattcct gcgtccctac tgcactcata gcctctgccc cgccaacagt gccgatgccg
    18601 ctacaaaatg cgatggtgaa aaataatgcc accagtgccg gaatgggcaa ttgtatccat
    18661 gcgcataaga ccgtgagcaa tgcacacaaa attgccgcta tcaggccacc tcgcaacaat
    18721 gtcatcgcgt taatccgtcg cgccaggcgc gagaagatcc atgaagcaat gataagtccg
    18781 gtgccgttaa ggccaaacac caggctaaat tgcattggac taaagccaaa ttccttctgc
    18841 aacacgaacg acgaagagcc gatatatgca aacaaaccgg ccagcataaa actttgaatc
    18901 aggcaaaagc gcataaaacg gcggttctgc accacgcttc gtccggttaa tagcaatgat
    18961 gagccccttt tattttctgg caaggtctca tgaataaata acagacagcc cagcaacagt
    19021 acggtgctaa tttcagccat tacccagaat aaagtgcgcc agtcaaaagt gctaacaatg
    19081 tacccgccca gcactggcga caacaccggt gccaggccat tcaccgtcat taacagcgca
    19141 aaaaactggg tcaacgttac tccctgatat ttgtcacgag caatagaacg agagagcacc
    19201 gaaccacccg cccccgcgat cccttgaata aaacgccaga ccaccagcca gtaaatattg
    19261 ttcgttgtcg cgcataaaat ggaagaaaca ataaacaata gcaacgacaa gattaacgga
    19321 cgtttacgcc ctattttgtc gctcagaggg ccaaataaca gttgtccgac gccaagacca
    19381 atcagtgatg cggtcagggt taattgcgtt atggtcgtgg ttgccgccag ttgctcagac
    19441 atctccggca aagccggcaa ataaagatcg gtacacatcg ggccgatacc ggctaaaaga
    19501 ccaagaatca atgcccatga aagagagact ctagccatat tattccttac ttgagtgatg
    19561 acataccgcc gcccagcgac tgccagagcg tgattcggtt tgtaaaatca gtcagttgca
    19621 gtgccagcag ctcctgctgt gcgctccaca agctgcgctg cgccgtcaac acggtcaggt
    19681 aatcaccaac acccgcctga tagcgacgca agccaacatc gaccgtttgt tgttcagctt
    19741 taacatactg gcgctgtgca tccagttgct cttcaagcgt ggtccgccgc gccagtgcgt
    19801 tagcgacatc tttaaatgcg ctctgaacgg ttttttcata ggtggcaatg agtccacgct
    19861 tttgtgcttc tgcgtaacga agctgcgcca gattacttcc gccagtaaac agcggtaatg
    19921 tgaccgatgg cgcaaatgac cagatctgca ttccgtggct gaacaacgac gacaacgcgt
    19981 cactgccaac accggcactg gcagtcagcg aaatcgtcgg gaaaaagtta gcccgcgccg
    20041 cgccaatatc tgcattggcg ctcttcaaat tatgttccgc ttcctggata tccgggcgac
    20101 gcagcagaac atcagatgat actcccgcag gaaccagact tatcatttgt tccggcaggc
    20161 tttccagtgt tcccggtagc agattttccg caagcgttgt acctgccagt aagttcagcg
    20221 catttttatc ctgcatcact tgtgtctgat agctggcaac gctggcgcgc gcttgctgat
    20281 aaacactcat cgcctcactg acatctgtcg ctgccgccgt gccaacctgt tgctggcgct
    20341 ggataatttt caatgagttt tctgcactgg ccatcgtttc ttttgccagg gccaggttgc
    20401 tgttatcagc cgccagtgtc agccaggcgg tgctgatttc agcaatcagc gttaaacgag
    20461 tgttctgggc tgtaaattca ctggcaagcc aggtttcccg cgccgcccga gataaactct
    20521 gattacgacc aaacagatct aacgtataac tggacaccgt gccgtcagcc tcggcagttg
    20581 ttcccgtacc attcgccagc gaacggctgc gggtcgaact taaggccgca ttcaccgtcg
    20641 gaaataacga cgcattagtt tgcccataga gcgcccgtgc tgagtcaata tcagcaatcg
    20701 ctttttgcac atcgcggtta ctgttcagtg caatggttac tacctgctgc aatcggggat
    20761 cgtggatcac ctgctgccag tcatggctga ttgccttccc ctggccctgt gctcccggca
    20821 aggtcgccgg gattggggat tcaggcgtac tgtagtgagg atcgagcgag acacatcccg
    20881 cactcaacaa caccagaaaa ataagagaac gacgcaacat aacttactcc tgacggcgcg
    20941 gtttaccggc aaacaaacgt ttcaccagta caaaaaacag aggaacgaag aaaatggcca
    21001 gtaatgtagc ggtcagcgtg ccgccaataa tgcccgtacc aatggcgatg cggctgttcg
    21061 cccctgcgcc ggttgctatc gccagcggca ttacccccgc aataaacgcc agcgaggtca
    21121 tgatgattgg gcgtaaacga gtctgcgccg cgcgtaatgc cgcacgactc aaggaatagc
    21181 cctctgcaac cgccgcttca gcaaattcca caatcagaat ggcgtttttc gacgacaagc
    21241 cgatagtagt taatagcgct acctggaagt aaacgtcgtt gtttaaatca cgcatccagg
    21301 ccgccagcgc cgcgccaaga agccccagag ggatcaccag aatgaccgag aacgggactg
    21361 accagctttc gtacagtgct gcaaggcaga ggaaaaccac cagaatagaa actgcataca
    21421 gacttaatgc ctgaccgctg gccagtttct cctgcaatga caaaccactc caggcccagg
    21481 ttgttcccgc aggaagactg tttgccagtt cctccatttt tgtcattgca tcgccggaac
    21541 taaagccagt cgcgttttcg ccctgaattt cataggctgc cgagccgttg tagcgcacca
    21601 gtctttccgg tccatacagc cagcgggtgg tcgcaaaagc agagaatggt gtcatggcgt
    21661 tatcgctgcc gcgcacaaac catttaccta agtctgacgg cgcggaacga aattcgctgt
    21721 cgccctgaat gtagactttt ttcacacgac cacggtcaat aaagtcattc acataagtac
    21781 cgccccacgc actggacagg gtgtcggtga catcattcaa actcaaccct aatgacaccg
    21841 ctttattact atcaatatct acctgcaatt gcggcatttg tggcaaatca ttggcgcgta
    21901 cagaatgtaa ctccggactt tgattcgctt tttctatcaa ctgattacgc atttgcagca
    21961 gtgtttcacg atcggttcca ccgttagcta acaattcaaa cgtaaaacca ttgctttggc
    22021 ccagcccatc aacggctggc ggcgtcatcg caaataccgt ggcatcacga attgtgccca
    22081 gctctttggt tgcccgtagg gcgatagcct gggcggtgtt ttctgcccct ttacgttgag
    22141 accagttttt caacgaaaca aacgccatcc cggtgttctg tccgctaccg ctaaaactga
    22201 aaccatcaac ggtaaagatg acatcggtat ttgctttctc gttaatcagg aaccagtcaa
    22261 caatctggcg attcacttct gctgtacggg cagcggtcgc cccggccggc agcgtgtact
    22321 gcaccatgat ttcgccctgg tcttcagtgg gtaagaaact gcccggcagt ttccacatca
    22381 tcagggccat tccaccaccc agcacgacat aaagccccat cgttcgggct gcacggcgca
    22441 ggacataaat tacgcctcgc tgatatttat cttcagtacg gcggtaaaag cggttaaatg
    22501 cgccgaaaaa gcctttttta tgtggtggaa catgctggag gacggaaccg cacagggcgg
    22561 gagtcaaggt caatgccacc accacggaaa gcagcattgc ggagatgatg gtgatggaga
    22621 actgacgata aattaccccc gtagatcccc caaagaaggc catcggcagg aatacggctg
    22681 acaacaccag cgcaatggca accagtgcgc cagaaatctc gcccattgat ttttccgtgg
    22741 cttcacgcgc gggcaaccct tcgtcacgca taatgcgttc gacgttctct accaccacaa
    22801 tggcatcgtc caccagcaag ccgatcgcca gcaccattgc aaacaacgtc agggtattaa
    22861 tcgaatagcc aaacaacgca agaacgccga atgtgcccag caaaacgacg gggacagcta
    22921 acgccggaat cagtgtggca cgcaggtttt gcaggaataa atacatcacg caaaccacca
    22981 atacgatggc ttcaaacagc gtctgaatta cgtcctctac ggagatttta ataaattcag
    23041 tgctgtcttt cgggtatgcg atgtcgtatc cctgcggcat gttccgctgg aattcggcaa
    23101 tcttatcctt gaccagcgtc gccgtattca gcgcattcgc accgggcgaa agcattacag
    23161 caaccccggc agacgggtga ccgttaagtt tgccgatagc ggtataatct tcactgccca
    23221 tctcaacgcg agccacatct tttatacgaa caactgcgcc gtctgactgg cttttcacga
    23281 taatattttt gaactgatcc accgtctgca agcgagactg cgcacgtacc gttgcggtca
    23341 gttgctgagt atccggtgaa ggcaatgccc ctattttccc ggcagtaacc tgcacgtttt
    23401 gcgcttcaat agcactttgc acgtctgaag gcatcagcga gtaagacgcc agtttggccg
    23461 ggtcaagcca gatgcgcata gcgtattccg cgccaaagac ttgcagactc cccacacctt
    23521 caacacgcgc cagcgggtcc tgaacgttac tgaccagcca gtcggcgata tccgaactgg
    23581 aggctttgtc agtggtgtca tacacggcag caatcagcaa aaagttgctt tgtgatttct
    23641 ccaccgtaac acccgtttgc tgcacttcgc tgggtaggcg cgactccgcc tgctgaattt
    23701 tattctgcac ctgaacctgt gcagtatctg gatcggtacc ttgttcaaag gtcacattaa
    23761 tactgaccga accatcagag ctactggttg agctgaaata gagtaaatta tcaagcccag
    23821 tgagttgttg ctcgataacc tgagtcacgc tgttctccag cgtttcggca gaagcaccag
    23881 tataagtggc tgaaatttta atggtcggcg gtgcaacgtc aggatattgc gcgacgggca
    23941 atgtgcgaat agccagaatc cctgccaaca taatcaaaat ggcgataacc caggcaaaga
    24001 ccgggcggcg aacaaaaaag cgcgaaaaca tcaggcgttg cctccattag cctgaacttc
    24061 aacagccttg acggtctgcc ctgaagtgac tttggcagaa ccttcaacaa tcagtcggtc
    24121 gccgttgtgc aggccgttca gcaccagcca tttatcacca tacgtttctc ccgtttcgag
    24181 cgttcgctgc tctactttat tgtctttatt caccaccagc gcagttgcat tgcctttagc
    24241 atcgcgcgta acgccctgtt gaggcgcgag aatagcgttt tccatcacgc cttcatcgac
    24301 acgagcgcga acaaacattc ccggtaataa ctgctgttgt ggattgggga aaattgcccg
    24361 taatgtcacc gaaccggtag actcatccac cgcgacttcg gtgagttcca gacgcccttt
    24421 ttcgctgtag gttgtgccat cttccagaat aagtgagacg ctcatggtgt cactgttggt
    24481 cgccagtgac tgtttacgca gacgtaataa atcgacactg gagcgagtga ggtcgacata
    24541 cattgtatcc agaccacgaa tagtcgttaa cgctgtatcc tgcgacgcgg tcaccagtgc
    24601 gccaggggtt accgacgaaa taccaatacg ccccgaaatc ggtgcggtta ccgtggtcca
    24661 gtcaagatta atgcgcgcag tttccagtgc ggcttttttc gcctctacac tggctttatc
    24721 ttgtgcacag gtagactgag catcatcagc atcctgttgt gaaacaccat tctctttcac
    24781 cagtcgggca taacgctgcg ctttctggca atcggctttt accagtgcct gtgcttgttg
    24841 taatgctgcc cgggcttcat tccatgcagc ctgataactg gccgcatcaa tctggtagag
    24901 aggctgtcca gccttgacca gatcaccttc cttaaataag cgtttctgga taattccccc
    24961 aacctgcgga cgtacttcag cactgagcgc agcactggtg cgtccggtta attcactgac
    25021 taccgaaacc ggttgagatt tgagcgtaac aacgccgact tctgtttctg acggggatga
    25081 attgttactt tgcgtattat cacaacccga taagagcagc attgccacta cagatgttgc
    25141 tatatacttc attattttct ccagggtgag aaataccctc ctcattgaaa ttaatgagga
    25201 tatgtcaggg atattcagtt ataacgaacc cgcatcgcga aatgaatttc gcaatgaaat
    25261 aagggggatt aatatccccc gctattggtt aattctgttc ttatttattt atcaacatac
    25321 taacaatatc ctgatatatt tcctgcagat gttgtggatc gcttttttgc ggtgttaaac
    25381 gacgataaac cgtaccttcc atcatggtag caaacacttc aacgcagcaa cgaatgtgct
    25441 cgtcgctaag atggggatgc attcttttca tatgtgcaca accgttagcg aacattctgg
    25501 cgtcagcttc ttcaagcatt gccataaccc gcgggttgcg tgtggcttct gcagccactt
    25561 ccagcatcag cgcgtcgtcg tcctcattta aggatttacg caaggcaagg acttccggga
    25621 agtgatcggt acgcgcgtca atgtccattt gggcaatacg aaagtcgatg atacggcgaa
    25681 ccatctcttc aataatggcg tctttgttgg cgaagtaacg atatatctga cccacgctaa
    25741 gctgagcttc gctggcaatt tgcgacatac tggcggcatg aaatccgcag cgacgaaaac
    25801 accgacgggc ggcgttaatg atttcatcct gacgctgttt gtggcgtatc tccagcttgc
    25861 tggtcatttc tgtctcctgg cctatcactt ggtgagaatg atcattctca tttttgctaa
    25921 ttatacgttt ctccaaagta atggaaagta tttttatctt attcatgatg catattctga
    25981 taatgaagag attgtggaga ttctgtgaag atagttgaca atattaagtt ggagtcaatt
    26041 catcagaaag acagcgactt gttgtcgcca gttctgtttt catcattaaa cttataggag
    26101 ctaatacgaa tagtttcaaa gtcagattct ataagatatt tccccaacct cccccttgca
    26161 ggcgtcagga gtagataacg caaaatgctc tgtaccgcag cttctctccg ctacagaaag
    26221 cgcaactata gccacccaca gccaggttga ttataataac cgtttatcag ttcgtactgt
    26281 ttactaaaac gacgaatcgc ctgattttca ggcacaacaa gcatcaacaa taaggattaa
    26341 agctatgggt tttctttccg gtaagcgcat tctggtaacc ggtgttgcca gcaaactgtc
    26401 catcgcctac ggtatcgctc aggcgatgca ccgcgaagga gctgaactgg cattcaccta
    26461 ccagaacgac aaactgaaag gccgcgtaga agaatttgcc gctcaattgg gttctgacat
    26521 cgttctgcag tgcgatgttg ccgaagatac cagcatcgac accatgttcg ctgaactggg
    26581 gaaagtttgg ccgaaatttg acggtttcgt acactctatt ggttttgcac ctggcgatca
    26641 gctggatggt gactatgtta acgccgttac tcgtgaaggc ttcaaaattg cccacgacat
    26701 cagctcctac agcttcgttg caatggcaaa agcttgccgc tccatgctga atccgggttc
    26761 tgccctgctg accctttcct accttggcgc tgagcgcgct atcccgaatt acaacgttat
    26821 gggtctggca aaagcgtctc tggaagcgaa cgtgcgctat atggcgaacg cgatgggtcc
    26881 ggaaggtgtg cgtgttaacg ccatctctgc tggtccgatc cgtactctgg cggcttccgg
    26941 tatcaaagac ttccgcaaaa tgctggctca ttgcgaagcc gttaccccga ttcgccgtac
    27001 cgttactatt gaagatgtgg gtaactccgc ggcattcctg tgctccgatc tctctgccgg
    27061 tatctccggt gaagtggtcc acgttgacgg cggtttcagc atcgctgcaa tgaacgaact
    27121 cgaactgaaa taatcgttct gttggtaaat attgggcggc gttctgccgc ccgttatctc
    27181 tgttatacct ttctgatatt tgttatcgcc gatccgtctt tctccccttc ccgccttgcg
    27241 tcaggataac gatttccttt acgaccaagg agcgcccatg gaacaacgcc acatcaccgg
    27301 caaaagccac tggtatcatg aaacgcaatc cagtactgcg gagtatgacg ttctgcctct
    27361 ggtcccggaa gccgcaaagg tcagcgatcc ctttctgctc gacgtgatcc ttgatgaaga
    27421 aacgctggcc cccttccttt catggctggt ccctgcgcgc gttcttgcag tggagttgtt
    27481 ccctgacccg cttaccgtga ctcgttcaca gaccttcacc gcttatgaac gcttgtcgac
    27541 ggccctgacg gttgctcagg tttgcggcgt ccaacggtta tgtaactact attctgcgcg
    27601 acttacgccg ctccccgggc ctgattcctc cagggaaagt aatcatcggt tggcacaaat
    27661 cacgcaatat gcccgccaac tggctagctc gccttctatt atcgacaacc gatcgcgcca
    27721 gcatctgaat gacgttggtc ttactgtctg tgactgtgtg atcattaacc aaatcattgg
    27781 ttttattggc tttcaggcgc ggaccattgc gacatttcag gcttatctcg ggcatccagt
    27841 acgctggtta cccgggctgg agatacaaaa ctacgccgac gcgtcactgt ttgctgatga
    27901 atcattacgc tggcgaagca gctatgaggt ggaaaaactc cctgaagagc acacaaaaag
    27961 ttcaactgca gaactttgcc aactggccaa cacactctct ctccacccta tttcactttc
    28021 ccttctcgaa aagttgttaa acagcacacg ggtcaataca cagccggata atcagcttgc
    28081 ggcgttgtta tgcgcgcgga taaatggcag tcctgcttgt tttgccgcct gtatgaattc
    28141 atcaaatgaa tataaaaaaa tcagccccct tctgcgcaag ggcgaaaatg aaattaaccg
    28201 atgggctgac cgtcattctg ttgagcgcgc taccgttcag gcgatacaat ggctgacccg
    28261 agcacccgat cgctttagcg ccgcccagtt cagcccatta ctcgaacacg aaaaatcatc
    28321 aacgcagatt attaatctgc tagtatggag cgggctgtgt ggctggataa atcgcttaaa
    28381 aatcgcgttg ggtgagacat attaaccttg ccgcgtcaga cagattcgcg taaaactgtc
    28441 agccgctcta atggccacca aaatagacaa ttatgtttca ggacaacccg ctgctagcgc
    28501 agcttaaaca gcaactgcat tcccagacgc cacgcgctga aggggtggta aaagccacag
    28561 aaaaaggctt tggcttcctg gaagtcgacg cgcaaaaaag ttatttcatt ccgccgccgc
    28621 agatgaaaaa agtcatgcat ggcgaccgaa ttatcgcggt gatccacagt gaaaaagaac
    28681 gtgaatccgc agagccagaa gaactggttg aaccgttcct gactcgtttc gtgggtaaag
    28741 ttcagggcaa aaatgaccgt ctggccatcg ttcctgacca tccactctta aaagacgcca
    28801 ttccttgccg cgcagcccgt ggcctgaacc acgagtttaa agaaggtgac tgggcggttg
    28861 ccgaaatgcg ccgtcatccg ctgaaaggcg atcgttcttt ctatgctgaa ctgacacaat
    28921 acatcacttt tggtgacgat cactttgtac cgtggtgggt tacccttgcg cgtcataatc
    28981 tggaaaaaga agcaccagac ggcgttgcta ccgaaatgct cgatgaaggt ctggttcgtg
    29041 aagatctgac tgcgctggat tttgtcacca tcgacagtgc cagcacagaa gatatggatg
    29101 acgccctttt cgccaaggcg ttaccggatg gcaaacttca gctgattgtg gcgattgccg
    29161 atccaaccgc gtggattgct gaaggcagca agctggacaa agccgcgaaa attcgcgcat
    29221 tcaccaacta tctgcctggc ttcaacatcc ctatgctgcc tcgcgagctt tctgacgatc
    29281 tctgctcact gcgcgccaat gaagtccgcc cggtactggc atgccgcatg acgctctcca
    29341 ctgatggcac cattgaagat aatatcgaat tctttgccgc caccatcgaa tccaaagcga
    29401 agctggtgta tgaccaggtt tctgactggc tggaaaatac cggtgactgg cagcctgaaa
    29461 gcgaagcaat tgccgaacaa gtccgtttgc tagcacaaat ttgccaacgc cgcggcgagt
    29521 ggcgtcataa ccacgcactg gtgtttaaag atcgcccgga ttaccgcttt attctcggtg
    29581 aaaaaggtga agtgctggat atcgtcgccg agcctcgtcg cattgccaac cgtatcgtcg
    29641 aagaagcgat gattgccgct aacatttgtg cggcccgcgt actgcgcgat aagctcggtt
    29701 ttggcatcta taacgtgcat atgggctttg atccggcgaa tgccgacgcg ctggcagcgt
    29761 tgctgaaaac gcacggtctg catgtcgatg ctgaagaagt gctcacgctg gacggtttct
    29821 gcaaactgcg tcgtgaactg gatgcgcaac caactggttt cctcgacagc cgcattcgtc
    29881 gcttccagtc atttgctgaa attagcactg aacccggtcc tcactttggc ctcggtctgg
    29941 aagcatacgc cacttggact tcgccgatcc gtaaatatgg cgacatgatc aaccaccgtc
    30001 tgctgaaagc ggttatcaaa ggcgaaactg cgacgcgtcc acaggatgaa atcactgtcc
    30061 aaatggccga gcgtcgccgt ctcaaccgga tggcagaacg tgatgttggc gactggttat
    30121 acgcacgctt cctgaaagac aaagccggga ccgacacccg tttcgcggcg gaaattgtcg
    30181 atatcagccg tggcggcatg cgtgttcgtt tggttgataa cggcgctatc gcctttattc
    30241 cagcaccttt cttacacgct gtgcgcgatg aactggtttg cagccaggaa aacggcactg
    30301 tacaaattaa aggtgaaacg gcttacaaag tgactgacgt tattgacgtc accattgccg
    30361 aagtccgcat ggaaacccgc agcattattg cgcgcccagt cgcgtaatct cctttcacgg
    30421 cccattcctc atggatgggc cgttt
//
LOCUS       DAFGPF010000057        29947 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFGPF010000057 DAFGPF010000000
VERSION     DAFGPF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29947
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.057"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..144
                     /gene="tuf"
                     /locus_tag="LSX49_002785"
     CDS             <1..144
                     /gene="tuf"
                     /locus_tag="LSX49_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312930.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL7169175.1"
                     /translation="VEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAK
                     VLS"
     gene            374..757
                     /gene="secE"
                     /locus_tag="LSX49_002786"
     CDS             374..757
                     /gene="secE"
                     /locus_tag="LSX49_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBL7169176.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            759..1304
                     /gene="nusG"
                     /locus_tag="LSX49_002787"
     CDS             759..1304
                     /gene="nusG"
                     /locus_tag="LSX49_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBL7169177.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1463..1891
                     /gene="rplK"
                     /locus_tag="LSX49_002788"
     CDS             1463..1891
                     /gene="rplK"
                     /locus_tag="LSX49_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBL7169178.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            1895..2599
                     /gene="rplA"
                     /locus_tag="LSX49_002789"
     CDS             1895..2599
                     /gene="rplA"
                     /locus_tag="LSX49_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBL7169179.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAE
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     IRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            2891..3388
                     /gene="rplJ"
                     /locus_tag="LSX49_002790"
     CDS             2891..3388
                     /gene="rplJ"
                     /locus_tag="LSX49_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBL7169180.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3455..3820
                     /gene="rplL"
                     /locus_tag="LSX49_002791"
     CDS             3455..3820
                     /gene="rplL"
                     /locus_tag="LSX49_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBL7169181.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4140..8168
                     /gene="rpoB"
                     /locus_tag="LSX49_002792"
     CDS             4140..8168
                     /gene="rpoB"
                     /locus_tag="LSX49_002792"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL7169182.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8245..12468
                     /gene="rpoC"
                     /locus_tag="LSX49_002793"
     CDS             8245..12468
                     /gene="rpoC"
                     /locus_tag="LSX49_002793"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBL7169183.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYTIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            complement(12710..13843)
                     /gene="thiH"
                     /locus_tag="LSX49_002794"
     CDS             complement(12710..13843)
                     /gene="thiH"
                     /locus_tag="LSX49_002794"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBL7169184.1"
                     /translation="MKTFSDRWRQLDWDDIHLRINGKTAADVERALNASQLTRDDMMA
                     LLSPAASGYLEPLAQRAQRLTRQRFGNVVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAEAEYAELKQLGLDGVMVYQETYHEATYAHHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDSWRVDCYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQAICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGRPSQRP"
     gene            complement(13840..14610)
                     /gene="thiG"
                     /locus_tag="LSX49_002795"
     CDS             complement(13840..14610)
                     /gene="thiG"
                     /locus_tag="LSX49_002795"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBL7169185.1"
                     /translation="MLHIADKTFDSHLFTGTGKFASSQLMVESIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVALLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA"
     gene            complement(14612..14812)
                     /gene="thiS"
                     /locus_tag="LSX49_002796"
     CDS             complement(14612..14812)
                     /gene="thiS"
                     /locus_tag="LSX49_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBL7169186.1"
                     /translation="MQILFNDQPMQCVAELTVHELLEQLEQQQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(14796..15551)
                     /gene="thiF"
                     /locus_tag="LSX49_002797"
     CDS             complement(14796..15551)
                     /gene="thiF"
                     /locus_tag="LSX49_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418420.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HBL7169187.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIRLMA
                     LQQRLTGETLKDAVAQADVVLDCTDNMATRQEINATCVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLTLRRASGCPVCGGCNADPV"
     gene            complement(15544..16179)
                     /gene="thiE"
                     /locus_tag="LSX49_002798"
     CDS             complement(15544..16179)
                     /gene="thiE"
                     /locus_tag="LSX49_002798"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709787.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBL7169188.1"
                     /translation="MYQPEFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDQR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAG
                     LRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYP
                     TVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE"
     gene            complement(16179..18074)
                     /gene="thiC"
                     /locus_tag="LSX49_002799"
     CDS             complement(16179..18074)
                     /gene="thiC"
                     /locus_tag="LSX49_002799"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBL7169189.1"
                     /translation="MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARKGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(18155..18255)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(18307..18783)
                     /gene="rsd"
                     /locus_tag="LSX49_002800"
     CDS             complement(18307..18783)
                     /gene="rsd"
                     /locus_tag="LSX49_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HBL7169190.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDDYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA"
     gene            18878..19651
                     /gene="nudC"
                     /locus_tag="LSX49_002801"
     CDS             18878..19651
                     /gene="nudC"
                     /locus_tag="LSX49_002801"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HBL7169191.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            19691..20755
                     /gene="hemE"
                     /locus_tag="LSX49_002802"
     CDS             19691..20755
                     /gene="hemE"
                     /locus_tag="LSX49_002802"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HBL7169192.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVASILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSEQYHR"
     gene            20765..21436
                     /gene="nfi"
                     /locus_tag="LSX49_002803"
     CDS             20765..21436
                     /gene="nfi"
                     /locus_tag="LSX49_002803"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HBL7169193.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALEWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            21479..22069
                     /locus_tag="LSX49_002804"
     CDS             21479..22069
                     /locus_tag="LSX49_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HBL7169194.1"
                     /translation="MLQNPIHLRLERLASWQHVTFMACLCERMYPNYAVFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            22256..22528
                     /gene="hupA"
                     /locus_tag="LSX49_002805"
     CDS             22256..22528
                     /gene="hupA"
                     /locus_tag="LSX49_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HBL7169195.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            22541..23236
                     /locus_tag="LSX49_002806"
     CDS             22541..23236
                     /locus_tag="LSX49_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HBL7169196.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALFLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGQKQQLSNDQIDLYRYRAAQIREISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(23238..23657)
                     /gene="zraP"
                     /locus_tag="LSX49_002807"
     CDS             complement(23238..23657)
                     /gene="zraP"
                     /locus_tag="LSX49_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HBL7169197.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGTGMGYGGCGGGGHMGMGHW"
     gene            23895..25271
                     /gene="zraS"
                     /locus_tag="LSX49_002808"
     CDS             23895..25271
                     /gene="zraS"
                     /locus_tag="LSX49_002808"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HBL7169198.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAA
                     ARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEEMAGQPGVRWFAVTDEQGTI
                     VMHSNSGMVGKQLYSPQEMQQLHPGDEEAWRRIDSADGEPVLEIYRQFQPMFAAGMHR
                     MRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRY
                     LRSGQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQL
                     AQVMAKEADRLNRVVSELLELVKPTHLALQAVELNTLISHSLQLVSQDANSREIQLRF
                     TANDTLPEIQADPDRLTQVLLNLYLNAIQAIGLHGVISVTASESGAGVKISVTDSGKG
                     IAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVN
                     ITRKDPQG"
     gene            25268..26593
                     /gene="zraR"
                     /locus_tag="LSX49_002809"
     CDS             25268..26593
                     /gene="zraR"
                     /locus_tag="LSX49_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HBL7169199.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSIDAETPAVSASQFGMVGKSPAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQTISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIP
                     LVQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(26590..27879)
                     /gene="purD"
                     /locus_tag="LSX49_002810"
     CDS             complement(26590..27879)
                     /gene="purD"
                     /locus_tag="LSX49_002810"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBL7169200.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLDFAQNEKVDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHNIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDEVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACEGKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVADGKVFHAGTKLADDEQVVTSGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(27891..29480)
                     /gene="purH"
                     /locus_tag="LSX49_002811"
     CDS             complement(27891..29480)
                     /gene="purH"
                     /locus_tag="LSX49_002811"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBL7169201.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKCLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DANEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERIPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTKRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
BASE COUNT         7020 a         7772 c         8254 g         6901 t
ORIGIN      
        1 gtagagatgg taatgccggg cgacaacatc aaaatggttg ttaccctgat ccacccgatc
       61 gcgatggacg acggtctgcg tttcgcaatc cgtgaaggcg gccgtaccgt tggcgcgggc
      121 gttgtagcaa aagttctgag ctaattgccg ataacatttg acgcaatgcg cactaaaagg
      181 gcatcatttg atgccctttt tgcacgcttt cgtaccagaa cctggctcat cagtgatttt
      241 ctttgtcata atcattgctg agacaggctc tgttgagggc gtataatccg aaaagctaat
      301 acgcgtttcg atttggtttg cctcgcgatc gcggggtgaa aatgtttgta gaatacttct
      361 gacaggttgg tttatgagtg cgaataccga agctcaagga agcgggcgcg gcctggaagc
      421 gatgaagtgg gtcgttgtgg tggcattgct cctggtagcg attgtcggca actaccttta
      481 tcgcgacatt atgctgccgc tgcgtgcgct ggccgtagta attctgattg ctgcagcggg
      541 tggtgtcgcg ctgttaacga caaaaggtaa agcaaccgtt gcttttgccc gtgaagcgcg
      601 taccgaagtc cgtaaggtca tttggccgac tcgccaggaa acattgcaca ccacgctgat
      661 tgtggctgcg gttaccgcag taatgtcact gatcctgtgg ggactggatg gtattctggt
      721 tcgcctggta tcctttatca ctggcctgag gttctgagat gtctgaagct cctaaaaagc
      781 gctggtacgt cgttcaggcg ttttccggtt ttgaaggccg cgtagcaacg tcgctgcgtg
      841 agcatatcaa attacacaac atggaagagt tgtttggtga agtcatggta ccaaccgaag
      901 aagtggttga aatccgtggc ggtcagcgtc gcaaaagcga acgtaaattc ttccctggct
      961 acgtcctcgt tcagatggtg atgaacgacg cgagctggca cctggtgcgc agcgtaccgc
     1021 gtgtgatggg cttcatcggc ggtacttccg atcgtcctgc gccaatcagc gataaagaag
     1081 tcgatgcgat tatgaaccgc ctgcagcagg ttggtgataa gccgcgtccg aaaacgttgt
     1141 ttgaaccggg tgaaatggtc cgtgttaatg atggtccgtt cgctgacttc aacggcgttg
     1201 ttgaagaagt tgattacgag aaatctcgtc tgaaagtgtc tgtttctatc ttcggtcgtg
     1261 cgacccctgt agagctggac ttcagccagg ttgaaaaagc ttaacccagc gatcaaaaaa
     1321 gcggcgattt aatcgttgca caaggcgcga gattggaata caatttcgcg ccttttgttt
     1381 ttatgggcct tgcccgtaaa acgatttttt atatcacggg gagcctctca gaggcgttat
     1441 tacccaactt gaggaattta taatggctaa gaaagtacaa gcctatgtca agctgcaggt
     1501 tgcagctggt atggctaacc cgagtccgcc agtaggtccg gctctgggtc agcagggcgt
     1561 aaacatcatg gaattctgca aagcgttcaa cgcaaaaact gattccatcg aaaaaggtct
     1621 gccgattccg gtagtaatca ctgtttacgc tgaccgttct ttcactttcg ttaccaagac
     1681 tccgccggca gcagttctgc tgaaaaaagc ggctggtatc aagtctggtt ccggtaagcc
     1741 gaacaaagac aaagtgggta aaatttcccg cgctcaactg caggaaatcg cgcagaccaa
     1801 agctgccgac atgactggtg ccgacattga agcgatgact cgctccatcg aaggtactgc
     1861 acgttccatg ggcctggtag tggaggacta agaaatggct aaactgacca agcgcatgcg
     1921 tgttatccgc gagaaagttg atgcaaccaa acagtacgac atcaacgaag ctatcgctct
     1981 gctgaaagag ctggcgactg ctaaattcgt agaaagcgtg gacgtagctg ttaacctcgg
     2041 catcgacgct cgtaaatctg accagaacgt acgtggtgca actgtactgc cgcacggtac
     2101 tggccgttcc gttcgcgtag ccgtatttac ccagggtgca aatgctgaag ctgctaaagc
     2161 tgcaggtgct gaactggtag gtatggaaga tctggctgaa cagatcaaga aaggcgaaat
     2221 gaactttgac gttgttattg cttctccgga tgcaatgcgc gttgttggcc agctgggcca
     2281 ggttctgggt ccgcgcggcc tgatgccaaa cccgaaagtg ggtactgtaa cgccgaacgt
     2341 tgctgaagcg gttaaaaacg ctaaagctgg ccagattcgt taccgtaacg acaaaaacgg
     2401 catcatccac accaccatcg gtaaagtaga ctttgacgct gacaaactga aagaaaacct
     2461 ggaagctctg ctggttgcgc tgaaaaaagc aaaaccgact caggcgaaag gcgtgtacat
     2521 caagaaagtt agcatctcta ccaccatggg tgcaggtgtt gcagttgacc aggctggcct
     2581 gagcgcttct gtaaactaat gcctttacgt gggcggtgat tttgtctaca atcttacccc
     2641 cacgtacgct aacgaaagtt agcagctaaa aagatttgtt cgttggagcc tggcctatcc
     2701 aggcctccgt cgaagaccgc aggagtttcg caagaaactt aatcccctgc gtagacggtg
     2761 acagaacgct aagattattc ttttatattc tggcttgttt ctgctcaccg taattaagac
     2821 gctctctccg tttggaggag tgaagtgagt tccagagatt ttctctggca aacatccagg
     2881 agcaaagcta atggctttaa atcttcaaga caaacaagcg attgttgctg aagtcagcga
     2941 agtagccaaa ggcgcgctgt ctgcagtagt tgcggattcc cgtggcgtaa ctgtagataa
     3001 aatgactgaa ctgcgtaaag caggtcgcga agctggcgta tacatgcgtg ttgttcgtaa
     3061 caccctgctg cgccgtgctg ttgaaggtac tccgttcgag tgcctgaaag acgcgtttgt
     3121 tggtccgacc ctgattgcat actctatgga acacccgggc gctgctgctc gtctgttcaa
     3181 agagttcgcg aaagcgaatg caaaatttga ggtcaaagcc gctgcctttg aaggtgagct
     3241 gatcccggcg tctcagatcg accgcctggc aactctgccg acctacgaag aagcaattgc
     3301 acgcctgatg gcaaccatga aagaagcttc ggctggcaaa ctggttcgta ctctggctgc
     3361 tgtacgcgat gcgaaagaag ctgcttaatc gcagttatct ttttaacgca ttcgcttacg
     3421 tataaactta ttctgatatt caggaacaat ttaaatgtct atcactaaag atcaaatcat
     3481 tgaagcagtt gcagctatgt ctgtaatgga cgttgtagaa ctgatctctg caatggaaga
     3541 aaaattcggt gtttccgctg ctgctgctgt agctgtagct gctggcccgg ttgaagctgc
     3601 tgaagaaaaa actgaattcg acgtaattct gaaagctgct ggcgctaaca aagttgctgt
     3661 tatcaaagca gtacgtggcg caactggcct gggtctgaaa gaagctaaag acctggttga
     3721 atctgcaccg gctgctctga aagaaggcgt gagcaaagac gacgcagaag cactgaaaaa
     3781 agctctggaa gaagctggcg ctgaagttga agttaaataa gccaaccctt ccggttgcag
     3841 cctgagaaat caggctgatg gctggtgact ttttagtcac cagccttttt gcgctgtaag
     3901 gcgccagtag cgtttcacac tgtttgacta ctgctgtgcc tttcaatgct tgtttctatc
     3961 gacgacttaa tatactgcga caggacgccc gttctgtgta aatcgcaatg aaatggttta
     4021 agcgtgatag caacaggcat tgcggaaagt gttccatttt ccggtcaaca aaatagtgtt
     4081 gcacaaactg tccgctcaat ggacagatgg gtcgacttgt cagcgagctg aggaacccta
     4141 tggtttactc ctataccgag aaaaaacgta ttcgtaagga ttttggtaaa cgtccacaag
     4201 ttctggatgt accttatctc ctttctatcc agcttgactc gtttcagaaa tttatcgagc
     4261 aagatcctga agggcagtat ggtctggaag ctgctttccg ttccgtattc ccgattcaga
     4321 gctacagcgg taattccgag ctgcaatacg tcagctaccg ccttggcgaa ccggtgtttg
     4381 acgtccagga atgtcaaatc cgtggcgtga cctattccgc accgctgcgc gttaaactgc
     4441 gtctggtgat ctatgagcgc gaagcgccgg aaggcaccgt aaaagacatt aaagaacaag
     4501 aagtctacat gggcgaaatt ccgctcatga cggacaacgg tacctttgtt atcaacggta
     4561 ctgagcgtgt tatcgtttcc cagctgcacc gtagtccggg cgtcttcttt gactccgaca
     4621 aaggtaaaac ccactcttcg ggtaaagtgc tgtataacgc gcgcatcatc ccttaccgtg
     4681 gttcctggct ggacttcgaa ttcgatccga aggacaacct gttcgtacgt atcgaccgtc
     4741 gccgtaaact gcctgcgacc atcattctgc gtgccctgaa ctacaccaca gagcagatcc
     4801 tcgacctgtt ctttgaaaaa gttatctttg aaatccgtga taacaagctg cagatggaac
     4861 tggtgccgga acgcctgcgt ggtgaaaccg catctttcga catcgaagct aacggtaaag
     4921 tgtacgtaga aaaaggccgc cgtattactg cgcgccacat tcgccagctg gaaaaagacg
     4981 acgtcaaact gatcgaagtc ccggttgagt acatcgcagg taaagtggtt gctaaagact
     5041 atattgatga gtctaccggc gagctgatct gcgcagcgaa catggagctg agcctggatc
     5101 tgctggctaa gctgagccag tctggtcaca agcgtatcga aacgctgttc accaacgatc
     5161 tggatcacgg cccatatatc tctgaaacct tacgtgtcga cccaactaac gaccgtctga
     5221 gcgcactggt agaaatctac cgtatgatgc gccctggcga gccgccgact cgtgaagcag
     5281 ctgaaagcct gtttgagaac ctgttcttct ccgaagaccg ctatgacctg tctgcggttg
     5341 gtcgtatgaa gttcaaccgt tctctgctgc gcgaagaaat cgaaggttcc ggtatcctga
     5401 gcaaagacga catcattgat gttatgaaaa agctcatcga tatccgtaac ggtaaaggcg
     5461 aagtcgatga tatcgaccac ctcggcaacc gtcgtatccg ttctgttggc gaaatggcgg
     5521 aaaaccagtt ccgcgttggc ctggtacgtg tagagcgtgc ggtgaaagag cgtctgtctc
     5581 tgggcgatct ggataccctg atgcctcagg atatgatcaa cgccaagccg atttccgcag
     5641 cagtgaaaga gttcttcggt tccagccagc tgtctcagtt tatggaccag aacaacccgc
     5701 tgtctgagat tacgcacaaa cgtcgtatct cggcactcgg cccaggcggt ctgacccgtg
     5761 aacgtgcagg cttcgaagtt cgagacgtac acccgactca ctacggtcgc gtatgtccaa
     5821 tcgaaacccc tgaaggtccg aacatcggtc tgatcaactc cctgtccgtg tacgcacaga
     5881 ctaacgaata cggcttcctt gagactccgt atcgtaaagt gaccgacggt gttgtaactg
     5941 acgaaattca ctatctgtct gctatcgaag aaggcaacta cgttatcgcc caggcgaact
     6001 ccaacctgga tgaagaaggc cacttcgtag aagacctggt aacttgccgt agcaaaggcg
     6061 aatccagctt gttcagccgc gaccaggttg actacatgga cgtatccacc cagcaggtgg
     6121 tatccgtcgg tgcgtccctg atcccgttcc tggaacacga tgacgccaac cgtgcattga
     6181 tgggtgcgaa catgcaacgt caggccgttc cgactctgcg tgctgataag ccgctggttg
     6241 gtacgggtat ggaacgtgct gttgccgttg actctggtgt aactgcggtt gctaaacgtg
     6301 gtggtgtcgt tcagtacgtg gatgcttccc gtatcgttat caaagttaac gaagacgaga
     6361 tgtatccggg tgaagcaggt atcgacatct acaacctgac caagtacacc cgttctaacc
     6421 agaacacctg tatcaaccag atgccgtgtg tgtctctggg tgaaccggta gaacgtggcg
     6481 acgtgctggc agacggtccg tccaccgacc tcggtgaact ggcgcttggt cagaacatgc
     6541 gcgtagcgtt catgccgtgg aatggttaca acttcgaaga ctccatcctc gtatccgagc
     6601 gtgttgttca ggaagaccgt ttcaccacca tccatattca ggaactggcg tgtgtgtccc
     6661 gtgataccaa gctggggccg gaagagatca ccgctgacat cccgaacgtg ggtgaagctg
     6721 cgctctccaa actggatgaa tccggtatcg tttacattgg tgcggaagtg accggtggcg
     6781 acattctggt tggtaaggta acgccgaaag gtgaaactca gctgacccca gaagaaaaac
     6841 tgctgcgtgc gatcttcggt gagaaagcgt ctgacgttaa agactcttct ctgcgcgtac
     6901 caaacggtgt atccggtacg gttatcgacg ttcaggtctt tactcgcgat ggcgtagaaa
     6961 aagataaacg tgcgctggaa atcgaagaaa tgcagctcaa acaggcgaag aaagacctgt
     7021 ctgaagaact gcagatcctc gaagcaggtc tgttcagccg tatccgtgct gtgctggtag
     7081 ccggtggcgt tgaagctgag aagctcgaca aactgccgcg cgatcgctgg ctggagctgg
     7141 gcctgaccga cgaagagaaa caaaatcagc tggaacagct ggctgagcag tatgacgaac
     7201 tgaaacacga gttcgagaag aaactcgaag cgaaacgccg caaaatcacc cagggcgacg
     7261 atctggcacc gggcgtgctg aagattgtta aggtatatct ggcggttaaa cgccgtatcc
     7321 agcctggtga caagatggca ggccgtcatg gtaacaaggg tgtaatttct aagatcaacc
     7381 cgatcgaaga tatgccttac gatgaaaacg gtactccggt agacatcgta ctgaacccgc
     7441 tgggcgtacc gtctcgtatg aacattggtc agatcctcga aacccacctg ggtatggctg
     7501 cgaaaggtat cggcgacaag atcaacgcca tgctgaaaca gcagcaagaa gtcgcgaaac
     7561 tgcgcgaatt catccagcgt gcgtacgatc tgggcgctga tgttcgtcag aaagttgacc
     7621 tgagtacctt cagcgatgaa gaagttatgc gtctggctga aaacctgcgc aaaggtatgc
     7681 caatcgcaac gccggtcttc gacggtgcga aagaagcaga aattaaagag ctgctgaaac
     7741 ttggcgacct gccgacttct ggtcagatcc gcctgtacga cggtcgcact ggtgaacagt
     7801 tcgaacgtcc ggtaaccgtt ggttacatgt acatgctgaa actgaaccac ctggtcgacg
     7861 acaagatgca cgcgcgttcc accggttctt acagcctggt tactcagcag ccgctgggtg
     7921 gtaaggcaca gttcggtggt cagcgtttcg gggagatgga agtgtgggcg ctggaagcat
     7981 acggcgcagc atacaccctg caggaaatgc tcaccgttaa gtctgatgac gtgaacggtc
     8041 gtactaagat gtataaaaac atcgtggacg gcaaccatca gatggagccg ggcatgccag
     8101 aatccttcaa cgtattgttg aaagagattc gttcgctggg tatcaacatc gaactggaag
     8161 acgagtaatt ctcgctcaaa caggtcactg ctgtcggggt aaaacccggc agcggattgt
     8221 gctaactccg acgggagcaa atccgtgaaa gatttattaa agtttctgaa agcgcagact
     8281 aaaaccgaag agtttgatgc gatcaaaatt gctctggctt cgccagacat gatccgttca
     8341 tggtctttcg gtgaagttaa aaagccggaa accatcaact accgtacgtt caaaccagaa
     8401 cgtgacggcc ttttctgcgc ccgtatcttt gggccggtaa aagattacga gtgcctgtgc
     8461 ggtaagtaca agcgcctgaa acaccgtggc gtcatctgtg agaagtgcgg cgttgaagtg
     8521 acccagacta aagtacgccg tgagcgtatg ggccacatcg aactggcttc cccgactgcg
     8581 cacatctggt tcctgaaatc gctgccgtcc cgtatcggcc tgctgctcga tatgccgctg
     8641 cgcgatatcg aacgcgtact gtacttcgaa tcctatgtgg ttatcgaagg tggtatgacc
     8701 aacctggagc gtcagcagat cctgactgaa gagcagtatc tggacgcgct ggaagagttc
     8761 ggtgacgaat tcgacgcgaa gatgggggcg gaagcaatcc aggccctgct gaagagcatg
     8821 gatctggagc aagagtgcga acagctgcgt gaagagctga acgaaaccaa ctccgaaacc
     8881 aagcgtaaaa agctgaccaa gcgtatcaaa ctgctggaag cgttcgttca gtctggtaac
     8941 aaaccagagt ggatgatcct gaccgttctg ccggtactgc cgccagatct gcgtccgctg
     9001 gttccgctgg atggtggtcg tttcgcgact tctgacctga acgatctgta tcgtcgcgtc
     9061 attaaccgta acaaccgtct gaaacgtctg ctggacctgg ctgcgccgga tatcatcgta
     9121 cgtaacgaaa aacgtatgct gcaggaagcg gtagacgccc tgctggataa cggtcgtcgc
     9181 ggtcgtgcaa tcaccggttc taacaagcgt cctctgaaat ctttggccga catgatcaaa
     9241 ggtaaacagg gtcgtttccg tcagaacctg ctcggtaagc gtgttgacta ctccggtcgt
     9301 tctgtaatca ccgtaggtcc atacctgcgt ctgcatcagt gcggtctgcc gaagaaaatg
     9361 gcgctggagc tgttcaaacc gttcatctac ggcaagctgg aactgcgtgg tcttgctacc
     9421 accatcaaag ctgcgaagaa aatggttgag cgcgaagaag ctgtcgtttg ggatatcctg
     9481 gacgaagtta tccgcgaaca cccggtactg ctgaaccgtg caccgactct gcaccgtctg
     9541 ggtatccagg catttgaacc ggtactgatc gaaggtaaag ctatccagct gcacccgctg
     9601 gtttgtgcgg catataacgc cgacttcgat ggtgaccaga tggccgttca cgtaccgctg
     9661 acgctggaag cccagctgga agcgcgtgcg ctgatgatgt ctaccaacaa catcctgtcc
     9721 ccggcgaacg gcgaaccaat catcgttccg tctcaggacg ttgtactggg tctgtactac
     9781 atgacccgcg actgtgttaa cgccaaaggc gaaggcatgg tgctgactgg cccgaaagaa
     9841 gcagaacgtc tgtatcgctc tggtctggct tctctgcatg cgcgcgttaa agtgcgtatc
     9901 accgagtatg aaaaagatgc taacggtgaa ttagtggcga aaaccagcct gaaagacacg
     9961 actgttggcc gtgccattct gtggatgatt gtaccgaaag gtctgcctta caccatcgtc
    10021 aaccaggcgc tgggtaaaaa agcaatctcc aaaatgctga acacctgcta ccgcattctc
    10081 ggtctgaaac cgaccgttat ttttgcggac cagatcatgt ataccggctt tgcatatgca
    10141 gcgcgttctg gtgcatctgt tggtatcgat gacatggtca tcccggagaa gaaacacgaa
    10201 atcatctccg aggcagaagc agaagttgct gaaattcagg agcagttcca gtctggtctg
    10261 gtaactgcgg gcgaacgcta caacaaagtt atcgatatct gggctgcggc gaacgatcgt
    10321 gtatccaaag cgatgatgga taacctgcaa actgaaaccg ttattaaccg tgacggtcag
    10381 gaagagaagc aggtttcctt caacagcatc tacatgatgg ccgactccgg tgcgcgtggt
    10441 tctgcggcac agattcgtca gcttgctggt atgcgtggtc tgatggcgaa gccggatggc
    10501 tccatcatcg aaacgccaat caccgcgaac ttccgtgaag gtctgaacgt actccagtac
    10561 ttcatctcca cccacggtgc tcgtaaaggt ctggcggata ccgcactgaa aacggcgaac
    10621 tccggttacc tgactcgtcg tctggttgac gtggcgcagg acctggtggt taccgaagac
    10681 gattgtggta cccatgaagg tatcatgatg actccggtta tcgagggtgg tgacgttaaa
    10741 gagccgctgc gcgatcgcgt attgggtcgt gtaactgctg aagacgttct gaagccgggt
    10801 actgctgata tcctcgttcc gcgcaacacg ctgctgcacg aacagtggtg tgacctgctg
    10861 gaagagaact ctgtcgacgc ggttaaagta cgttctgttg tatcttgtga caccgacttt
    10921 ggtgtatgtg cgcactgcta cggtcgtgac ctggcgcgtg gccacatcat caataaaggt
    10981 gaagcaatcg gtgttatcgc ggcacagtcc atcggtgaac cgggtacaca gctgaccatg
    11041 cgtacgttcc acatcggtgg tgcggcatct cgtgcggctg ctgaatccag catccaggtg
    11101 aaaaacaaag gtagcatcaa gctcagcaac gtgaagtcgg ttgtgaactc cagcggtaaa
    11161 ctggttatca cttcccgtaa caccgaactg aaactgatcg acgaattcgg tcgtaccaaa
    11221 gaaagctaca aagtacctta cggtgcggta ctggcgaaag gcgatggcga acaggttgct
    11281 ggcggcgaaa ccgttgcaaa ctgggacccg cacaccatgc cggttatcac cgaagtaagc
    11341 ggttttgtac gctttactga catgatcgac ggccagacca ttactcgtca gaccgacgaa
    11401 ttgaccggtc tgtcttcgct ggtggttctg gattccgcag aacgtaccgc aggtggtaaa
    11461 gatctgcgtc cggcactgaa aatcgttgat gctcagggta acgacgttct gatcccgggt
    11521 accgatatgc ctgcgcagta cttcctgccg ggtaaagcga ttgttcagct ggaagatggc
    11581 gtacagatca gctctggtga caccctggcg cgtattccgc aggaatccgg cggtaccaag
    11641 gacatcaccg gtggtctgcc gcgcgttgcg gacctgttcg aagcacgtcg tccgaaagag
    11701 ccggcaatcc tggctgaaat cagcggtatc gtttccttcg gtaaagaaac caaaggtaaa
    11761 cgtcgtctgg ttatcacccc ggtagacggt agcgatccgt acgaagagat gattccgaaa
    11821 tggcgtcagc tcaacgtgtt cgaaggtgaa cgtgtagaac gtggtgacgt aatttccgac
    11881 ggtccggaag cgccgcacga cattctgcgt ctgcgtggtg ttcatgctgt gactcgttac
    11941 atcgttaacg aagtacagga cgtataccgt ctgcagggcg ttaagattaa cgataaacac
    12001 atcgaagtta tcgttcgtca gatgctgcgt aaagctacca tcgttaacgc gggcagctcc
    12061 gacttcctgg aaggtgaaca ggttgaatac tctcgcgtca agatcgcaaa ccgcgaactg
    12121 gaagcgaacg gtaaagtggg tgcaacttac tcccgcgatc tgctgggtat taccaaagcg
    12181 tctctggcaa ccgagtcctt catctccgcg gcatcgttcc aggagaccac tcgcgtgctg
    12241 accgaagcag ccgttgcggg caaacgcgac gaactgcgcg gcctgaaaga gaacgttatc
    12301 gtgggtcgtc tgatcccggc aggtaccggt tacgcgtacc accaggatcg tatgcgtcgc
    12361 cgtgctgcgg gtgaagctcc ggctgcaccg caggtgactg cagaagacgc atctgccagc
    12421 ctggcagaac tgctgaacgc aggtctgggc ggttctgata acgagtaatc gttaatccgc
    12481 aaataacgta aaaacccgct tcggcgggtt tttttatggg tgttattcag agggcaaagt
    12541 cttcacggga aatattaaga aaggcagggc gaaacgagga agaagctttt cgccctggac
    12601 aacattcctg ctgacggcac taccataaaa aaacacaacg ctttcaacaa ccttgcgttt
    12661 ttcatcttcc gtagcggctc ggaataaatt tacgttctta cattctgtct catggccttt
    12721 gcgatgggcg tcccagatag ctgtcccagt ctttccatac cggctgcaaa ccctgagcgg
    12781 ttaacgcggc agcaaccgct tccggtctgc gatcgtcgtg cggtgagaac tgttccagct
    12841 cggggtggtt gtcggcatag ccacctggct gcgttttcga aaaagcgctg acgttattaa
    12901 ttgccagcgg aatcacgcga tcgcgaaacc acggtgattc ccgcgtggag agtgacagtt
    12961 caatctccgg tgcaagcagc cggaaagcgc agatggcttg cactaactgg cgttcatcca
    13021 taatcgacgc aggctcaatg ccgccagtac atggacgcag gcgtgggaag gagacagagt
    13081 agcggctttg ccagtaatgc tgttgcagcc atagcaaatg ttcggcaacc atatagcagt
    13141 caactcgcca gctgtcggaa aggccgatta gcgcgccgag gcctatctta tcaatccccg
    13201 cacgccctag ccgatccggc gtttccagcc gccagaagaa gtcctgtttt ttacctttca
    13261 gatgatgatg ggcataagtc gcctcatgat atgtctcctg ataaaccatt actccatcga
    13321 ggccaagctg ttttaactcg gcatattccg cctccgccag cggttgcact tccatctgta
    13381 gtgaagagaa ctgttcacgc agggcaggga gatgacgacg aaagtaatcc atccccactt
    13441 tcgcctgatg ttcaccagtg actaatagca gatgttcaaa gcccatctcc cgtatagcgg
    13501 cgctttccct ggcaatatcc gcttcatcca gcgttttgcg cttgatgcgg ttgctcatag
    13561 aaaatccgca ataagtacag tcgttagcgc aaagattgga aagataaagc gggacgtaga
    13621 agctgacgac gttgccaaat cgctgacgag tcagacgttg cgctcgctgg gccagtggtt
    13681 ccagatagcc actggcggcg ggtgatagca atgccatcat gtcgtcgcgg gtgagttgcg
    13741 aggcatttag cgcccgctct acgtcagcag ccgttttgcc gttgatacgc aggtggatgt
    13801 catcccagtc cagttgtcgc cagcgatcgc tgaaggtttt catgccgatg cctccagaaa
    13861 tccagtcagc gggctggtgg catgagcaaa atgactgcgg ctgcccggtc cggactgacg
    13921 tgccagcagg cctgcttcta ccgccagacg aaatgccttc gccatgttga cgggatcgtc
    13981 cgcgacggca atcgccgtat tcactaacac cgcgtcggcc cccatttcca gcgcctgcgc
    14041 ggcatggctg ggaacgccga tgccagcatc gacaaccacc ggaacggtgg cctgctggat
    14101 aataatctcc agcatggcgc gggtttccag tccctgattc gagccaatcg gcgcgccgag
    14161 cggcatcacc gctgcacagc cgacttcttc cagacgttta cacaataccg gatcggcccc
    14221 gcagtaaggc agcacgacaa atccctgttg taccagcgtt tcggcggctt tcagggtttc
    14281 gatgggatcg ggcaacagcc agcgggcgtc agggtgaatc tccaatttta gccagtttgt
    14341 gcctaacgct tcacgtgcca gatgggcggc gaaaatggct tcttccgcgg ttttcgcccc
    14401 ggaagtattc ggcagcaggg ccacacccgc cgcgataagc ggttcgagga tagcgtcgtt
    14461 gtgctggcgc aagtcgacac gtttcatcgc cagcgtcacc agttggctgc cggaagcgcg
    14521 aatagactcc accatcagtt gtgaagaggc gaattttccg gtgccagtaa acagatgtga
    14581 atcaaacgtt ttgtccgcaa tatgtaacat ctcaaccccc tgcaataact tgaaaaagca
    14641 ggatctggtc gccatcctgc acgatatgtt gcgcccattg ttcccgcggg acgatttgct
    14701 gattaatcgc cagtgccgca cctgcttgtt gttgttcgag ttgctccagc agttcgtgaa
    14761 cagttagttc ggcgacacac tgcatcggtt gatcgttaaa caggatctgc attgcatcct
    14821 ccacataccg ggcaaccgct ggcgcggcgc aacgtcagac tgcgccactg gctcgattta
    14881 ccgtcgaaca gtcggagttc tcccgcaggc gtctctatac cacttaataa cttaatcgct
    14941 tccagtgcct gtaaagtgcc cataaccccg accaccgggc caaccacgcc cgccgtgcgg
    15001 cagttgcgtt ctggctcctg gttatctggc cacaggcagc ggtaacatcc ctgctcccag
    15061 ggcggcgtca gtaccatcaa ctgaccgcca aatccgaccg cgctggcggt gataagcggc
    15121 gtgttgagtg ccacgcaggt ggcattaatc tcctggcgag tcgccatatt gtcagtacag
    15181 tcgagcacca catcggcttg tgcaaccgca tcttttaacg tctcacccgt taaccgttgt
    15241 tgtaatgcca tcagtcgaat atcgggattc aactgtgtca gtcgctgttg gctgacctgt
    15301 gatttcgggc gatcgatatc ttcagtggta aagaggattt gtcgttgcag attgcttaaa
    15361 tgcacatcgt cgtcatctgc cagtaccagc gtcccgacgc cagcccccgc caggtatagc
    15421 gcagcaggtg tacccagccc gccaagacca ataatcagca cctggctgtc gagcagtttt
    15481 tgctgcccgt ccagagcgat atcgtcgagc aggatttggc ggctataacg cataaagtca
    15541 cggtcattca tcgccaactc ctgcaatttc cagcagctgt gccgttgcca aacgccagtc
    15601 tgcggcttga gtaatggcgc tgacgacggc gatactgccg acacccgttg ctatcaccgc
    15661 aggcgcgcgc gccagactga taccgccaat cgccacggtg ggataatccg ccaggcgctc
    15721 aacatgccgt gccagctgtt ccagtccctg cggtgcagaa ggcatctgtt tggtttgtgt
    15781 cggaaacaca tgtcccagcg cgatataaga aggacgtgcc gccagcgcga cgtcgatctc
    15841 catatcgtca tgagtcgaaa cgcccagccg caggcccgct gcacggatgg cattgagatc
    15901 ggtggcttgc aaatcttcct gccccagatg gacgccatac gcctgatgct taatcgccag
    15961 ccgccagtaa tcgttgataa acaatcgcgc gttatagcgg cggcccagcg caattgccgc
    16021 caccacatcg gcttctacct cttcatcgcg ctgatctttg atgcgtagct ggagagtacg
    16081 tacgcctgca tccaacagac gttcgatcca ctgtacgctg tcaaccaccg ggtacagtcc
    16141 taaacgaaag ggtacaggag gaaactcagg ctgatacatc acgcttcctc cttacgcagg
    16201 tagatttctc cgcctctggc gcggaagttc tccgacatat ccgccattcc cacttcaatg
    16261 gtttgcgcgg cggcgtaatc acgcacttcc tggctgattt tcatcgagca gaatttcggt
    16321 ccacacatgg agcaaaaatg ggcgacttta ccggactctt gcggcagggt ttcatcgtga
    16381 taagcgcggg cagtaaacgg gtcgagggcc agattaaact ggtcttccca gcgaaattcg
    16441 aagcgggctt tcgacatggc gttatcgcga atttgcgcgc ccggatgccc tttcgccagg
    16501 tcggcggcgt gagcggcaat cttataggtg ataagcccct gtttaacatc ttctttattt
    16561 ggcaggccca gatgctcttt cggcgttacg tagcagagca tcgcgcagcc aaaccagcca
    16621 atcatcgccg cgccaatccc tgacgtgaag tggtcatagc ccggcgcgat atcggtagtt
    16681 agcggcccca gagtgtaaaa cggcgcttcg tggcagtgct ctaactcctc ggtcatattg
    16741 cggcgaatca tctgcatcgg cacgtggcct gggccttcaa tcatcacctg cacgtcatat
    16801 tcccaggcga ttttggtcag ttcgcccagc gtatgcagct cggcaaactg tgcttcatcg
    16861 ttggcgtcct gaatagaacc ggggcgcagg ccgtcgccca gcgacagcga aacgtcataa
    16921 gcagcacaga tttcacaaat ttcgcggaag tgttgataga ggaaattttc ctgatgatgg
    16981 gagaggcacc atttcgccat aatcgaaccg ccgcgagaga cgataccggt caggcgtttc
    17041 gcggtcatcg gcacgtagcg cagcagcacc cccgcatgga tagtgaagta atccacacct
    17101 tgctcggctt gttccagcag ggtgtcgcgg aagacttccc aggtaagatc ttcagcgatc
    17161 ccgttcacct tctccagtgc ctggtagatc ggcactgtac cgatcggcac cgggctgtta
    17221 cgcaaaatcc actcgcgggt ttcgtgaata tagcgaccag tggaaagatc catcacggta
    17281 tccgctcccc agcgcgtgga ccataccagt ttttccactt cttcttcgat ggaagaagtg
    17341 accgccgagt tgccgatatt ggcgttaact tttaccagga agttacggcc aataatcatc
    17401 ggctccgatt ccggatgatt aatgttggcc gggataatcg cacgtccggc agcaacttca
    17461 tcacggacaa attccgcagt gatattttcc ggcagacgtg cgccaaagct cattcccgga
    17521 tgctggtggc gtaaaacttc gctacgtatg cgctcgcgac ccatattctc gcgaatggcg
    17581 atgaattcca tttctggcgt gatgataccc ttgcgggcgt agtgcagttg ggtgacgcgg
    17641 cgtcctgctt tggcgcgttt tggcgttaat acgccgctaa aacgcagctc gtcaaggcca
    17701 tcatctgcca gccgcgcttt agtgtaatcg gaactgcgta cggtaagttc ttcggtatcg
    17761 ccgcgcgcat cgatccacgg ctggcgtagt tttgccagcc cttgctgcac gttaatggca
    17821 atctgcggat cgccatacgg gccggaggtg tcgtagaccg gaatcgcttc gttttcttcg
    17881 tactgcggct gttctttgct gccgccaatt agcgtcgggc taagctggat ctcacgcatc
    17941 ggcacgcgca cgccggggtg tgtgccagtg atgtaaatgc gttttgagtt gggaaaggcg
    18001 gagccttcca gggtgtcgat aaaatgttgg gcctgggcgc gctgttcgcg gcgggtcagt
    18061 tttgttgcag acatagctca ttccaaaaag ttaaggacgt ggcttgtcag acgacggatg
    18121 aagcaagaga cgatcgccgc aaaggcgatg cgatagcaga ttaactcttg ttcccttcgc
    18181 aggtattagc ctgatcaggt tccgcggatc ccgaataaac ggtctcagcc agttaaggca
    18241 ctccgacaag aaattagccc cacaaacggg gcgttgaatg taaattacgc gttaacagcg
    18301 cagaactcaa gcaggatatt tgacgcgggc ggcgtcaagc accagtagaa tcagcttatc
    18361 ttccagcaca aagcgcgctt ccagtgcctc gccgatgtca gataaaacct gttgaaactc
    18421 aaggtaatta tcatgatcga tggcggtttc caggctggaa tcgtagtcat ccataatctg
    18481 ttgagtattg gcttcgagtt gcggccaaat cttcgcggcg cgcgcgagtt gcccgttgcc
    18541 ttccagctta tgaagaatgc gctcataaat actgaaatgt ccggcagaca agtaatcgac
    18601 caggctctga caaaaatcat caagggcttt ttcgtttagc ctcatgtacg attctttgcc
    18661 aggcttaatg ccaaccagat tgtagtaagc cacgagcaga tgcttacgta catgtagcca
    18721 gcgatcaacc agtttgttac ttcctctgac gcgctccgtc aggttatcga gctggttaag
    18781 catgattgac tccgcaagtt tgtattcaaa aactgctctg tgagaaatgt aaaaaccatg
    18841 ttaaacatgc cagtgatgca aaggtagtgc aagagctatg gatcgtataa ttgaaaaatt
    18901 agatcacggc tggtgggtcg tcagccatga acaaaaatta tggttgccga agggagaatt
    18961 gccatatggc gaagcggcaa atttcgatct tgtgggtcag cgcgcactac aaatcggcga
    19021 atggcagggg gaacctgttt ggttagtaca acagcagcgg cgtcacgata tggggtcggt
    19081 acgtcaggtc attgatctcg atgttgggct gtttcaactg gccggacgtg gcgtgcaact
    19141 ggcggagttt taccgatcgc ataaatactg tggttactgc gggcatgaaa tgtatccaag
    19201 caaaaccgaa tgggcgatgc tgtgcagcca ttgccgtgag cgttactacc cgcaaatcgc
    19261 cccctgcatt attgttgcca tccgtcgcga tgattcgatc ctcctcgccc agcatacccg
    19321 ccatcgtaac ggtgtccata cagtacttgc cggattcgtc gaagtgggtg aaaccctcga
    19381 gcaggcagtc gcgcgggaag tgatggaaga gagcggaatt aaagttaaaa acttgcgtta
    19441 cgtgacctcc caaccgtggc cgtttcctca gtcgttaatg accgcgttta tggcggaata
    19501 tgacagcggc gagatcgtga tcgacccgaa agaattgctt gaggcgaact ggtatcgcta
    19561 tgacgatttg ccgttactcc cgccgcccgg caccgtagcg cgccgtctga tagaagatac
    19621 ggtggcgatg tgtcgggcag agtatgagtg atgatacact gaccgcctga cgcactaagg
    19681 aacagccaaa atgaccgaac ttaaaaacga tcgttatctg cgggcgctgc tgcgccagcc
    19741 cgttgatgtc actccagtat ggatgatgcg ccaggcgggt cgctatctac cggaatataa
    19801 agccacgcgc gcccaggcgg gcgattttat gtcgctgtgc aaaaatgccg agctggcgtg
    19861 cgaagtgact ttgcaaccgc tgcgtcgcta tccgctggat gcggcgatcc tcttttccga
    19921 tatcctcacc gtgccagacg cgatgggttt agggctctat tttgaagccg gagaaggtcc
    19981 gcgttttacc tcgccagtca cctgcaaagc cgatgtcgat aaactgccaa ttccggaccc
    20041 ggaagatgag ctgggttacg tgatgaacgc ggtgcgtacc attcgtcgcg aactgaaagg
    20101 cgaagtgccg ctgattggtt tttccggcag cccgtggacg ctggcgacct acatggtgga
    20161 aggcggcagc agcaaagcgt tcaccgtgat caaaaaaatg atgtatgccg atccacaggc
    20221 gctgcacgcg ctactcgata aactggcgaa aagcgtcact ttgtatctga atgcgcagat
    20281 taaagccggt gctcaggcag tgatgatttt cgacacctgg ggcggcgtgc ttaccgggcg
    20341 cgattatcaa cagttctcgc tctattacat gcataaaatt gttgatggtt tactgcgtga
    20401 aaacgacggt cgccgcgtac cggtcacgct gtttaccaaa ggtggcggac agtggctgga
    20461 agcgatggca gaaaccggtt gcgatgcgct gggcctcgac tggacaacgg acatcgccga
    20521 tgcgcgccgt cgcgtgggca ataaagtcgc gctgcagggt aatatggacc cgtcgatgct
    20581 gtatgcgccg cctgcccgca ttgaagaaga agtggcgtct atacttgccg gtttcggtca
    20641 cggcgaaggc catgtcttta accttggtca cggcattcat caggatgtgc cgccagaaca
    20701 tgctggcgtg tttgtggagg cagtgcatcg cttgtctgaa cagtatcacc gctaaggagc
    20761 gattatggat ctcgcgtcat tacgcgctca acaaattgaa ctggcttctt ctgtgatccg
    20821 cgaggatcga ctcgataaag atccgccgga tctgatcgcc ggagccgatg tcggatttga
    20881 gcagggcgga gaagtgacgc gagcggcgat ggtgctgctg aaatacccct cgcttgagct
    20941 ggtggagtat aaagtggccc gcatcgccac caccatgcct tacattccag gttttctctc
    21001 gttccgcgaa tatcctgcgc tgctggcagc gtgggagatg ctgtcgcaaa agccggattt
    21061 agtgtttgtc gatggtcatg ggatctcgca tcctcgccgt cttggcgtag ccagccattt
    21121 tggcttattg gtggatgtgc cgaccattgg cgtggcgaaa aaacggctct gcggtaaatt
    21181 cgaaccgctc tccagcgaac cgggcgcgct ggcccctctg atggataaag gcgagcagct
    21241 ggcctgggtc tggcgcagca aagcgcgctg taacccgttg tttatcgcta ccggccatcg
    21301 ggtcagcgtg gacagcgcgc tggagtgggt acaacgctgc atgaaaggct atcgtctgcc
    21361 ggagccaacg cgctgggcgg acgcggtggc ctcggaacgt ccggcgttcg tgcgctatac
    21421 agcaaatcag ccctaattca ggtaaactgc ggataatttc cgtatttgag aactcaacat
    21481 gttacaaaac ccaattcatc tgcgtctgga gcgcctggca agctggcagc atgtcacttt
    21541 tatggcctgc ttatgcgaac gcatgtaccc caattacgcc gtattctgtc agcaaaccgg
    21601 cttcggcgat gggcagattt accgccgcat tctcgatctc atttgggaaa cgctgaccgt
    21661 caaagatgca aaagtaaatt tcgacagcca actggagaaa tttgaagaag cgattccttc
    21721 agccgacgat ttcgatctgt acggcgttta tccggcaatc gatgcttgcg tggcgttaag
    21781 tgaactggtt cattcgcgtt taagtggcga aacgctcgaa cacgcggtgg aagtgagtaa
    21841 gacctccatc acgaccgttg cgatgctgga aatgactcag gctggtcgcg aaatgagcga
    21901 tgaagagctc aaagaaaacc cagctgtaga gcaagaatgg gacattcagt gggaaatatt
    21961 ccgactttta gctgagtgtg aagaacgcga tatcgagctg ataaaaggcc ttagggcaga
    22021 cctgcgtgag gcgggtgaga gcaatattgg tataattttt cagcaataag accagaaaac
    22081 gtgatttaac gcctgatttg tcgtacctgg agtcttccct ttcgcccccc gtctggtcta
    22141 catttggggg gcgaaaaaaa gtggctatcg gtgcgtgtat gcaggagagt gctattctgg
    22201 catttccgtc gcactcgatg cttagcaagc gataaacaca ttgtaaggat aacttatgaa
    22261 caagactcaa ctgattgatg taattgcaga gaaagcagaa ctgtccaaaa cccaggctaa
    22321 agctgctctg gagtccactc tggctgcaat tactgagtct ctgaaagaag gcgatgctgt
    22381 acaactggtt ggtttcggta ccttcaaagt gaaccaccgc gctgagcgta ctggccgcaa
    22441 cccgcagacc ggtaaagaaa tcaaaattgc cgcagctaac gtaccggcat ttgtttctgg
    22501 caaggcactg aaagacgcag ttaagtaaga ttgcgtggca gtgaacagtt ttaacgaagg
    22561 ggtggtttca ccccttttgt ctttctggcg tcgatcattg atgctggcag gtgcgctgtt
    22621 tctcactgcc tgtagtcaca actcttcact tcctcccttt accgccagtg gatttgctga
    22681 agaccagggc gcggtacgca tctggcgaaa agacagcggc gataatgtgc atcttcttgc
    22741 cgtgtttagc ccgtggcgca gtggcgatac gacgacgcga gagtatcgct ggcagggcga
    22801 taacctcacg cttatcaata tcaacgttta cagcaaaccg ccggtaaaca tccgggcgcg
    22861 ttttgacgat cgcggtgact tgagctttat gcaacgtgaa tccgacgggc aaaagcagca
    22921 gctttccaat gatcagatcg atttataccg ttatcgtgcc gcgcagatcc gcgagattag
    22981 cgatgcctta cgccagggga gagtcgtgct gcgccagggg cgctggcatg cgatggagca
    23041 gactgtgacc acctgcgaag ggcaaaccat taaacctgat ttagattcgc aggcgatagc
    23101 gcatatcgag cgccgccaga gccgttcttc tgttgatgtc agcgtggcat ggctggaagc
    23161 gcccgaaggt tcgcaattac tgttggtggc aaactctgat ttctgtcgct ggcaacccaa
    23221 cgagaaaacg ttctgattta ccagtggccc atacccatat gaccgccacc accgcagccg
    23281 ccgtaaccca ttccggtacc gcgcggaata cccgcttcag ccatcgcaat atctcgtttc
    23341 acccgtaact catctaacga ctgacgcaaa ttctccatct ctttggcgac cgcgttaatt
    23401 ttgctgctat ccggtgggtt cgcggctaac agggcattgt attcataacg ctttgtcacc
    23461 agttgctgtt gcagtgcgct gctttgagcg taaaagtcat tatggatttt ctgccacgct
    23521 gtttgttgtt cgctggtcaa aggcgcggca ttttgctgcc acataccgtg tccgccgtga
    23581 gcaaatgccg atgtcgatcc catcgccatt gctgaaagcg ccatcattac cagggcaatt
    23641 ttcgtgttcc gtttcatggt taatcctcca gtggttgtct tacttcgggt attgcatctt
    23701 tcgtgccaac ggcgaaacgc tgatatgacg ggtaatctgg catgataaac gagtaaaaat
    23761 gactcgcctg ttgtgggtag cgagtcattt ttactcattg aaacttaagc ctttgtgtta
    23821 cagcgcaggg taagcgctga taaaagatgg catgatttct gctgtcagaa agggatgggc
    23881 aggcaaagaa gaagatgcgt tttatgcaac gttctaaaga ctccttagct aaatggttaa
    23941 gcgcgatcct ccccgtggtc attgttgggc tggtggggct gtttgcggtg acagtgattc
    24001 gcgattatgg gcgcgagact gccgccgcca gacaaacgct gctggaaaaa ggcagtgtac
    24061 ttatccgtgc tctcgaatcc ggctcgcgcg tcggaatggg gatgcgcatg catcatgcgc
    24121 agcagcaggc cttactggaa gaaatggccg ggcagcctgg agtacgttgg tttgcggtca
    24181 cggatgaaca aggaacaatc gtgatgcata gcaactccgg catggtggga aaacagcttt
    24241 attccccgca ggaaatgcag cagttacatc cgggagatga agaagcgtgg cggcggatcg
    24301 atagcgcaga cggcgagcct gttctggaaa tttatcgcca gtttcaaccg atgtttgctg
    24361 ctggaatgca ccggatgcgc catatgcagc agtatgccgc gacaccacaa gcaattttta
    24421 tcgctttcga cgccagtaac attgtgagtg ccgaagatcg tgagcagaga aacaccctga
    24481 ttatcctctt cgccctggcg acggtcttgc tggcaagcgt gttgtcattc ttctggtatc
    24541 gccgatatct gcgctcgggc cagctgttgc aggatgaaat gaagcgcaaa gagaagctgg
    24601 tggcactggg gcatcttgcg gcaggcgttg cccacgaaat ccgtaaccca ctttcctcga
    24661 ttaaagggct ggcgaaatac tttgccgaac gcgcgccagc agggggagaa gcgcatcaat
    24721 tggcgcaggt gatggcgaaa gaagccgacc gtttaaaccg cgtggtaagc gagctgctgg
    24781 aactggttaa gccaacgcat ctggctttgc aggcggtgga gctcaacacg ctgattagcc
    24841 actcattaca gctggtaagc caggatgcaa acagccggga gatccagtta cgctttaccg
    24901 ccaacgacac attaccggaa attcaggccg atccggacag gctgactcag gtcctgttga
    24961 atctctatct caacgctatt caggcgattg gtctgcatgg cgtgattagc gtgacggcca
    25021 gcgaaagcgg cgcgggcgtg aaaatcagcg ttaccgacag cggtaaggga attgcggcgg
    25081 atcagcttga agccatcttc actccgtact tcaccaccaa agccgaaggc accggactgg
    25141 ggctggcggt cgtgcataat attgttgaac aacacggtgg tacaattcag gttgcaagcc
    25201 aggaggggaa aggcgcaacg ttcaccctct ggcttccggt caatattacg cgtaaggacc
    25261 cacaaggatg acgcacgata atatcgatat tctggtggtg gatgatgaca ttagccactg
    25321 cactattttg caggctttac tgcgcggctg gggctataac gtcgcgctgg cgaacagcgg
    25381 gcgacaggcg ctggagcagg tgcgggaaca ggttttcgat cttgtgcttt gcgatgtgcg
    25441 aatggcagag atggacggca tcgccacgct aaaagagatc aaagcgttaa atccggcgat
    25501 tccggtactg attatgaccg cgtactccag cgtcgagacg gcggtagagg cactgaaaac
    25561 cggggcgctg gattacctca tcaagccgct ggatttcgat aacctgcagg caacgctgga
    25621 aaaggcgctc gcgcatacgc acagtatcga cgctgaaacg cctgcggtgt ctgccagcca
    25681 gttcggtatg gtcggtaaaa gcccggcgat gcaacacctg ctcagtgaaa tcgccctcgt
    25741 cgcgccatcg gaagccacgg tgctgatcca cggcgattcc ggtaccggta aagagctggt
    25801 cgccagggcg attcacgcca gtagcgcacg tagcgaaaaa ccgctggtaa cgctcaactg
    25861 tgcggcactc aacgaatcct tgctggaatc tgaattgttc ggtcatgaaa aaggggcgtt
    25921 taccggagcc gacaaacggc gagaagggcg ctttgttgag gcggacggcg gcacgctgtt
    25981 tctcgatgag attggcgata tctcgccgat gatgcaggtt cgtctgctgc gtgcgattca
    26041 ggagcgcgaa gtgcaacgtg tcggcagcaa ccagactatc tcggttgatg tccggctgat
    26101 tgcggcgacc catcgcgatc ttgccgcaga ggtgaatgcc gggcgttttc gccaggatct
    26161 ctactatcgg ctgaacgtgg tggcgattga agtaccatcg ctgcggcaac ggcgggaaga
    26221 tattcctctg ctggctggcc attttcttca gcgctttgcc gaacgtaatc gcaaggcggt
    26281 aaaaggcttt acgccccagg cgatggatct gctgattcat tacgactggc cgggaaatat
    26341 tcgtgaactg gaaaacgcgg tggaacgggc ggtggtgctg ctgaccgggg aatatatttc
    26401 cgaacgcgag ctgccgctgg cgattgccag tacgccgatc ccgctggtac aaagtcagga
    26461 tattcagccg ctggtggaag tcgaaaaaga ggtgattctg gcggcgctgg agaaaacggg
    26521 cggcaacaaa accgaagccg cccgccagtt agggatcacg cgcaaaacgc tattggcaaa
    26581 actgtcgcgt tagttctgct cgcgttcgat agcgcgccag ccgatatctt tccggcagaa
    26641 gcagtcgtcc caatggatat cggtcattaa ggcataagcg cgtttctgcg cttctgccac
    26701 ggtatgaccc agcgcggtaa cgcacagtac gcgcccgccg ctggtcacta cctgctcgtc
    26761 atccgccagt ttcgtgcccg cgtggaacac tttgccgtct gccacttctt ccagcggcag
    26821 gccgtggatc acatcgccgg tgcggtaatc gcccggatat ccacccgcag ccatcaccac
    26881 gccgagagaa gcgcgttcat cccactcgga cgttttctcg tccagcttgc cttcacaggc
    26941 cgccaggcag agctcaacca gatcggactt catgcgcagc ataatcggct gggtttccgg
    27001 atcgccaaag cggcagttaa attcaataac ctttggatta ccctgtttgt cgatcatcag
    27061 gcccgcatag agaaaaccgg tgtaggtgtt gccttccgcc gccatgcctt tcacggttgg
    27121 ccagatgata cgttccatgg tgcgctgatg aacttcatcg gtcactaccg gcgcaggaga
    27181 gtaagccccc attccgccgg tgtttggccc ggtatcttta tcgcctacgc gtttgtgatc
    27241 ctggctggtg gccatcggta gcacatgctc gccgtccacc atcacgataa agctcgcttc
    27301 ttcaccgtcg aggaactctt cgataacaat acgatgaccc gcgtcgccaa acgcgttgcc
    27361 cgccagcata tcgtgaacag ctgcttcagc ttcttccagc gtcatcgcca cgataacgcc
    27421 tttcccggct gccagaccgt cagctttaat gacgattggc gcgcctttct cacgcagata
    27481 tgccagcgca ggttctacct cggtgaagtt ctggtattcc gctgtgggaa tgttatggcg
    27541 ggccagaaag tctttggtga atgctttaga accttccagt tgtgcagcac ctgcggttgg
    27601 gccgaagatt ttcagcccgg cggcgcggaa ggtatcgact acgcctttca ccagcggcgc
    27661 ttccgggccg acgatggtta gatctacctt ttcgttttgt gcgaaatcca gcagcgccgg
    27721 gatatcggtt acgccgatag cgacgttctg tagcgcgggt tccagcgcag tgcctgcatt
    27781 gcccggagca acaaaaacag tttcaaccag cggcgactga gccgctttcc aggccagcgc
    27841 gtgctcgcgc ccgccgttac cgatcactaa tactttcatc tgtcgctcca ttaatggcgg
    27901 aagtggcgca tgtcggtgaa gagcatcgca ataccgtgct cgtcggcggc ggcaattact
    27961 tcgtcatcac ggatagaacc gccaggctgg attacgcagg tcacgcccgc agcggctgcg
    28021 gcatcaatac cgtcgcggaa cgggaagaac gcgtcagaag ccattgacga acctttcact
    28081 tccaaacctt catcggcagc tttaataccg gcgattttcg cggagtacac gcggctcatc
    28141 tggcctgcgc caataccgat ggtcatattg tttttggcat agacgatagc gttggatttc
    28201 acgaacttcg ccactttcca gcagaacagc gcatcacgaa gttcctgttc agtcggctga
    28261 cgtttggtga cgacgcgcag ttcttccgca ccgaccatcc ccagatcgcg atcctgaacc
    28321 agtagaccgc cgttcacgcg tttgaaatca agacccggaa tacgttcgcc ccactgaccg
    28381 caggtcagaa cgcgtacgtt ctgcttggcg gcggtgattt tcagggcttc ttcgctggcg
    28441 gacggcgcaa taatcacttc gacgaactga cgagaaatga tggcctgcgc ggtttcagca
    28501 tccagttcgc ggttaaaggc aatgatgccg ccgaatgcgg aggttgggtc ggttttgtac
    28561 gcgcgatcgt aagcatcaag aatggaattg ccgatagcca cgccgcaagg gttggcgtgc
    28621 ttcacaatca cacatgccgg ctcggcgaac tctttcacgc actccagcgc cgcatcggta
    28681 tcggcgatgt tgttataaga gagagcttta ccctgaacct gggttgcggt agcaacggag
    28741 gcttctttca cattctcttc tatatagaag gcagcctgct ggtggctgtt ctcgccgtaa
    28801 cgcatatcct gcttcttaat gaagttcagg ttcagcgtgc gtgggaagcg accggcggct
    28861 tctttgcttt caccgtggta agccggaacc atgctgccga agtagttggc aatcatgctg
    28921 tcgtaggcgg cagtgtgttc gaaggctttg atggcgaggt cgaaacgggt tgcaagcgtc
    28981 agcgatcctt cgttggcatc catctcttta ataatggcgt cgtagtcgct gctcttcacc
    29041 acgattgcga catctttatg gttcttggcg gcggagcgca ccatcgttgg gccgccgata
    29101 tcgatgttct ctaccgcatc ttccagcgag cagccttcac gagcgacggt ctgggcgaac
    29161 ggatacaggt taacaaccac catatcgata ggctggatct gatgttcttc cataatggca
    29221 tcgtcctggc cgcgacggcc cagaatgcca ccatgtactt tcggatgcag ggtcttcacg
    29281 cgtccatcca tcatctccgg gaaaccggtg taatcggaaa cttcggttac cggcagacat
    29341 ttttctgcta acagacgggc agtgccccct gtagacagca gctccacacc gcgtgcggaa
    29401 agtgcctggg cgaattcgac gataccggct ttgtcagaaa cactgagcag agcgcggcgg
    29461 actggacgac gttgttgcat ggtaaatccc ctggatttga ctattacaga gagcgttagc
    29521 tgaatttttc gcgaaaaact cagctaacgc ccctaacggg gcatccttat ttttcgcccg
    29581 cattgtaacg aaaacgtttg cgcaacgctc gcgaattttt ctctttcaat ggtgatcaca
    29641 attttgacag tggctaccgt gggaaaaata cagaaattac attgatgatt gtggataact
    29701 ctgtgtgtaa aaaggtataa agcggggttt tgctggggaa tgcagcagtc agtcattttt
    29761 ctgcaatttt tctattgcgg cctgcggaga actccctata atgcgcctcc atcgacacgg
    29821 cggatgtgaa tcacttcaca caaacagccg gttcggttga agagaaaaat cctgaaattc
    29881 agggttgact ctgaaagagg aaagcgtaat atacgccacc tcgcgacagt gagctgaaag
    29941 ccgcgtc
//
LOCUS       DAFGPF010000058        29335 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFGPF010000058 DAFGPF010000000
VERSION     DAFGPF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29335
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.058"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(210..755)
                     /gene="orn"
                     /locus_tag="LSX49_002812"
     CDS             complement(210..755)
                     /gene="orn"
                     /locus_tag="LSX49_002812"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HBL7169202.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
     gene            850..1902
                     /gene="rsgA"
                     /locus_tag="LSX49_002813"
     CDS             850..1902
                     /gene="rsgA"
                     /locus_tag="LSX49_002813"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HBL7169203.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMEFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            1999..2967
                     /gene="psd"
                     /locus_tag="LSX49_002814"
     CDS             1999..2967
                     /gene="psd"
                     /locus_tag="LSX49_002814"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HBL7169204.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVDLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            2989..6312
                     /gene="mscM"
                     /locus_tag="LSX49_002815"
     CDS             2989..6312
                     /gene="mscM"
                     /locus_tag="LSX49_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HBL7169205.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VVEALQSALNALEERKGSLERIKQYQEVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     NDALNQEILQISSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTEQLAESSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPANANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(6343..6657)
                     /locus_tag="LSX49_002816"
     CDS             complement(6343..6657)
                     /locus_tag="LSX49_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeO family protein"
                     /protein_id="HBL7169206.1"
                     /translation="MSARMSVLCCIWFIVAFLWITITSALDKEWMIDGRGINNVCDVL
                     MYLEDDDTRDVGVIMTLPLFFPFLWFALWRKKRGWFMYATALAIFGYWLWQFFLRYQF
                     CL"
     gene            complement(6755..8257)
                     /gene="yjeM"
                     /locus_tag="LSX49_002817"
     CDS             complement(6755..8257)
                     /gene="yjeM"
                     /locus_tag="LSX49_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HBL7169207.1"
                     /translation="MPHSIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAISFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWHIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGVTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTRMSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRVVKNPQWVAE"
     gene            complement(8476..9453)
                     /gene="epmA"
                     /locus_tag="LSX49_002818"
     CDS             complement(8476..9453)
                     /gene="epmA"
                     /locus_tag="LSX49_002818"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HBL7169208.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            9778..11586
                     /gene="frdA"
                     /locus_tag="LSX49_002819"
     CDS             9778..11586
                     /gene="frdA"
                     /locus_tag="LSX49_002819"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HBL7169209.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGMAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            11579..12313
                     /gene="frdB"
                     /locus_tag="LSX49_002820"
     CDS             11579..12313
                     /gene="frdB"
                     /locus_tag="LSX49_002820"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HBL7169210.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            12324..12719
                     /gene="frdC"
                     /locus_tag="LSX49_002821"
     CDS             12324..12719
                     /gene="frdC"
                     /locus_tag="LSX49_002821"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HBL7169211.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            12730..13089
                     /gene="frdD"
                     /locus_tag="LSX49_002822"
     CDS             12730..13089
                     /gene="frdD"
                     /locus_tag="LSX49_002822"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HBL7169212.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            13152..14285
                     /locus_tag="LSX49_002823"
     CDS             13152..14285
                     /locus_tag="LSX49_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HBL7169213.1"
                     /translation="MFKTTLCTLLITASCSTFAAPQQINDIVHRTITPLIEQQRIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMKTRVFQPLKLNHTWINVPSAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKILQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDIIINGSDNKIALAARPVKPITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNTLQ"
     gene            14374..14907
                     /gene="blc"
                     /locus_tag="LSX49_002824"
     CDS             14374..14907
                     /gene="blc"
                     /locus_tag="LSX49_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HBL7169214.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDREMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(14904..15221)
                     /gene="sugE"
                     /locus_tag="LSX49_002825"
     CDS             complement(14904..15221)
                     /gene="sugE"
                     /locus_tag="LSX49_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBL7169215.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(15397..15543)
                     /gene="ecnB"
                     /locus_tag="LSX49_002826"
     CDS             complement(15397..15543)
                     /gene="ecnB"
                     /locus_tag="LSX49_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HBL7169216.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            complement(15654..15779)
                     /gene="ecnA"
                     /locus_tag="LSX49_002827"
     CDS             complement(15654..15779)
                     /gene="ecnA"
                     /locus_tag="LSX49_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HBL7169217.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            complement(15831..16397)
                     /gene="efp"
                     /locus_tag="LSX49_002828"
     CDS             complement(15831..16397)
                     /gene="efp"
                     /locus_tag="LSX49_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBL7169218.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            16439..17467
                     /gene="epmB"
                     /locus_tag="LSX49_002829"
     CDS             16439..17467
                     /gene="epmB"
                     /locus_tag="LSX49_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HBL7169219.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPNDPLLRQVITSQDEFVVAPGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            17702..18571
                     /locus_tag="LSX49_002830"
     CDS             17702..18571
                     /locus_tag="LSX49_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HBL7169220.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSAMELR
                     DLLIALESRLHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELTDDQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQDDGNLEYDTYSQPEWKHNLFNHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEVEAITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
     gene            complement(18621..18974)
                     /locus_tag="LSX49_002831"
     CDS             complement(18621..18974)
                     /locus_tag="LSX49_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HBL7169221.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PTDSQIIGQVYKCPN"
     gene            complement(19112..20758)
                     /gene="groL"
                     /locus_tag="LSX49_002832"
     CDS             complement(19112..20758)
                     /gene="groL"
                     /locus_tag="LSX49_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBL7169222.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            complement(20802..21095)
                     /locus_tag="LSX49_002833"
     CDS             complement(20802..21095)
                     /locus_tag="LSX49_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBL7169223.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            21371..22627
                     /gene="yjeH"
                     /locus_tag="LSX49_002834"
     CDS             21371..22627
                     /gene="yjeH"
                     /locus_tag="LSX49_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HBL7169224.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPANIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEQMAAAASLPKIVVQLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLFLPKRKTPENGITT"
     gene            complement(22643..23119)
                     /gene="fxsA"
                     /locus_tag="LSX49_002835"
     CDS             complement(22643..23119)
                     /gene="fxsA"
                     /locus_tag="LSX49_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HBL7169225.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDDRDRLDHKDDRQD"
     gene            23456..24892
                     /gene="aspA"
                     /locus_tag="LSX49_002836"
     CDS             23456..24892
                     /gene="aspA"
                     /locus_tag="LSX49_002836"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HBL7169226.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            25010..26311
                     /gene="dcuA"
                     /locus_tag="LSX49_002837"
     CDS             25010..26311
                     /gene="dcuA"
                     /locus_tag="LSX49_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HBL7169227.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            26427..26765
                     /gene="cutA"
                     /locus_tag="LSX49_002838"
     CDS             26427..26765
                     /gene="cutA"
                     /locus_tag="LSX49_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HBL7169228.1"
                     /translation="MLDEKSSNTTSVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            26741..28438
                     /gene="dsbD"
                     /locus_tag="LSX49_002839"
     CDS             26741..28438
                     /gene="dsbD"
                     /locus_tag="LSX49_002839"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HBL7169229.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNEASQPVSVPQQEQPT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFIMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDIWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDSQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP"
     gene            28475..29050
                     /locus_tag="LSX49_002840"
     CDS             28475..29050
                     /locus_tag="LSX49_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL7169230.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            29157..29232
                     /locus_tag="LSX49_002841"
     tRNA            29157..29232
                     /locus_tag="LSX49_002841"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29190..29192,aa:Phe,seq:gaa)
BASE COUNT         7235 a         7662 c         7386 g         7052 t
ORIGIN      
        1 tactacttaa ttttgctttc gtaattttcg catttctgcg tcgttacggg aggcgcatta
       61 tacgagaaat ctttccctct gcaacccccc taaaaaattt tttttgagtt tttatctcaa
      121 gtgctgaaat tatcagcaag gcgttcaatt tagcgtcaaa atcacgccgc cgcaagtgga
      181 ttccggcgct tacgtgacca ggaaaaattt tacagcttga taaaatgctc gcggtagtaa
      241 gccaactccg ccaccgattc acggatatca tccatcgcct gatgcgtccc ctgcttggta
      301 aagccgtcaa gaatttccgg cttccagcgg cgcgccagct ctttcagggt gctaacatcg
      361 agatagcggt agtggaagta ggcttccagc tccggcatgt atttaaacag gaagcgacgg
      421 tcctgaccga tgctgttacc acaaatcggc gattttcccg caggcaccca ctgttttaag
      481 aattcgagcg ttgccagttc agcttcacga tcgcccatcg tgctcgcttt cacacgctct
      541 accagcccgc tggcggtatg ggtgcgcacg ttccagtcat ccatcagcgc cagctgttca
      601 tcggactgat gtactgcaat ggtcggccct tctgccagaa tattcaggtt ggcatcggtc
      661 accagcgtgg caatctcaat aatgcgatcg cgctcgggat ccagaccggt catctcaaga
      721 tcgatccaaa tcaggttgtt ttcattggca ctcatgctat tttccaccca ttcacagtga
      781 ctatattgat ccacaattgc gtgtatcata gatgttttgc ccatcagggg cgaccaggag
      841 tctgtacgat tgagtaaaaa taaactctcc aaaggccagc agcgccgcgt gaacgccaat
      901 caccagcgtc gtcttaaaac gtctaaggag aagcccgact acgacgacaa tctgtttggc
      961 gagcctgatg aaggtatcgt catcagccgc tttggtatgc acgctgatgt ggaatccgcc
     1021 gatggcgacg ttcaccgctg caatattcgc cgtaccatcc gttcgttggt gaccggcgac
     1081 cgcgtagtct ggcgtccggg taaaccggcg gcggaaggcg taaatgtcaa agggatcgtg
     1141 gaagcggtgc atgagcgcac ctcagtgttg acgcgcccgg atttctacga cggtgtgaaa
     1201 cctattgctg ccaacatcga ccagattgtc attgtctccg ccattttgcc ggagctgtcg
     1261 ctcaatatta tcgaccgtta cctggtggcc tgcgaaacct tgcagattga gccgattatt
     1321 gtgctcaaca agatagacct gctggacgac gaaggcatgg agttcgtcaa cgagcagatg
     1381 gatatctacc gcaatatcgg ttatcgcgta ttgatggttt ccagtcatac tcaggatggg
     1441 ctgaaaccgc tggaagaggc gttgaccggg cgcatcagca tttttgccgg gcagtctggc
     1501 gttggcaaat ccagcctgct gaacgcgttg ctgggtctgc aaaaagagat cctgaccaac
     1561 gatgtctctg acaactcggg gcttggtcag cacaccacga ccgccgcacg actgtatcac
     1621 ttcccgcacg gcggtgatgt gattgattcc ccaggtgtgc gtgagtttgg tctctggcac
     1681 ctggagccgg aacaaatcac tcagggcttt gtcgaattcc atgactattt aggtctgtgt
     1741 aaatatcgcg attgcaaaca cgataccgat ccgggctgcg ctatccggga agcggttgag
     1801 gaagggaaaa tcgcggaaac ccgtttcgaa aactatcacc gtattctgga aagcatggcg
     1861 caggtaaaaa cgcgtaaaaa cttttctgat acggatgact gacaattaag ctaaccgtcg
     1921 ttagaatcgt cccctttttt tcaggatccg gcatgtaggc cggatcagga acgacaaaac
     1981 aatggcctgg aggctacctt gttaaattca tttaaacttt cgctacagta cattctgccg
     2041 aaactatggc ttactcgcct ggcgggttgg ggcgcaagca agcgggcagg atggctgaca
     2101 aaactggtta tcgatctgtt cgttaaatac tacaaggtcg acatgaaaga ggcgcaaaag
     2161 ccggacaccg ccagctaccg cacctttaac gaattctttg tccgtccgct gcgtgatgaa
     2221 gtacgcccaa tcgataccga tccgaatgtc ctggttatgc ctgccgatgg cgttatcagc
     2281 cagttgggta aaatcgaaga agataaaatc ctgcaagcca aaggccacaa ctacagcctc
     2341 gaagccctgc tggcaggcaa ctatctgatg gcggatctct tccgtaacgg tacgtttgtg
     2401 accacttacc tctccccacg tgactaccac cgcgtacaca tgccgtgcaa cggtattctg
     2461 cgtgaaatga tctacgtgcc gggcgatctc ttctccgtta accatctcac ggctcagaac
     2521 gtgccgaatc tgtttgcccg taacgaacgc gtgatctgcc tgttcgatac cgaatttggc
     2581 ccgatggcgc agattctggt cggtgcgacg attgtaggca gcattgagac ggtatgggcg
     2641 ggcaccatta cgccgccgcg cgaaggcatc atcaagcgct ggacctggcc tgccggggaa
     2701 aacgacggtt ctgtggcact gctgaaaggc caggaaatgg gtcgctttaa actaggctct
     2761 accgttatca acctgtttgc accaggtaaa gtggacctgg ttgagcaact ggagagcctg
     2821 tctgtcacga aaattggcca gccgctggca gtatctaccg aaacctttgt tacgccagat
     2881 gctgaaccag ccccgcttcc tgctgaagag atcgaagcag aacacgacgc cagcccattg
     2941 gttgacgata aaaaagacca ggtctaatcc atcaaaggaa acgctgacgt gcgcctgatt
     3001 atcacttttc tgatggcctg gtgcctcagt tggggggcgt acgccgcgac ggcccccgat
     3061 agcaaacaaa tcacccagga actggagcag gcaaaagcgg cgaaacctgc gcagccggaa
     3121 gtcgtagagg cgctccagtc tgccttaaat gcgcttgagg aacgaaaagg ttcccttgag
     3181 cgcatcaagc aatatcaaga agtcattgat aattacccga aactttccgc cactctgcgc
     3241 gcgcagttaa acaacatgcg tgacgagcca cgcagcgtgt cgccgggaat gtctaacgat
     3301 gcgctgaatc aggaaattct ccagatcagc agtcagttgc tggataaaag ccgtcaggcc
     3361 cagcaagagc aggagcgcgc ccgcgagatt gccgattccc tgaatcaact gccgcaacag
     3421 caaaccgatg cccgccgtca gttgaatgaa atcgagcgcc gcctggggac gcttaccggc
     3481 aataccccgc tcaatcaggc acaaaatttc gcgttgcagt ctgactccgc acgtctgaaa
     3541 gcgctcgttg atgaactgga gctggcgcag ctatctgcca ataaccgcca ggaattagcg
     3601 cgcttgcgct cagagctggc cgaaaaagag agccagcagc tggatgcata tttgcaagca
     3661 ctacgcaacc agttgaatag tcaacgccaa ctggaagcgg aacgggcgct ggaaagtacc
     3721 gagcaactgg cggaaagtag cgccgatttg ccaaaagata tcgtcgccca gtttaaaatt
     3781 aaccgcgaac tatcggcggc actgaatcaa caggcgcagc ggatggatct cgttgcctcg
     3841 caacagcgtc aggctgccag ccagacgtta caggtccggc aggcgttgaa tacgctgcgt
     3901 gaacagtcgc aatggctggg atcatctaac ctgctcggcg aagcgttgcg ggcgcaggtg
     3961 gcacggctac cggaaatgcc aaaaccacaa cagcttgata ccgaaatggc gcagttacgt
     4021 gtgcaacggt tacgttatga ggatctgctt aataaacagc cgctgctacg gcaaatccat
     4081 caggccgacg gtcagccgct gaccgctgag caaaaccgta ttctggaagc acagctacgc
     4141 actcagcgtg agttgctgaa ctcattgttg cagggtggcg acacgctact gctggagctg
     4201 accaagctga aagtctccaa cgggcaactg gaggatgcac tgaaagaggt gaacgaagcg
     4261 acgcaccgct atctgttctg gacctctgac gtgcgcccga tgaccatcgc ctggccgctg
     4321 gaaatcgccc aggatctgcg tcgtctcatt tcgctggaca ccttcagtca gttgggcaaa
     4381 gccagtgtga tgatgctgac cagtaaagag acgattttgc cgctgtttgg cgcgttgatt
     4441 ctggtcggtt gcagtattta ctcgcgccgc tatttcaccc gttttcttga acgttcggcg
     4501 gcgaaagtcg gcaaagtgac tcaggatcac ttctggctga cgttacgcac tcttttctgg
     4561 tcgattctcg tcgcgtcacc gctgcctgtg ctgtggatga cgctgggtta cggcttgcgc
     4621 gaggcgtggc cttatccgct ggcggtcgcg attggtgatg gcgtaacagc caccgtgccg
     4681 ctgctgtggg tagtgatgat ttgcgccacc tttgctcgcc cgaacggctt gtttatcgct
     4741 cattttggct ggccgcgcga acgtgtttcc cgtgggatgc gttactacct gatgagcatc
     4801 gggcttattg tgccgctgat tatggcgctg atgatgttcg ataacctcga cgaccgcgaa
     4861 ttttccggtt cgctgggacg gctttgcttt atcctcattt gcggtgcgct ggcggtggtc
     4921 accctcagcc tgaaaaaggc cgggatcccg ctgtatctca acaaagaagg cagcggcgac
     4981 aacattacca accatatgct gtggaacatg atgattggcg cacctctggt tgccattctg
     5041 gcgtcggcgg tgggttatct ggcaacggcg caggcgctgt tagcgaggct tgaaacctcg
     5101 gttgccatct ggttcctgct actggtggtt tatcacgtta tccgccgctg gatgctgatc
     5161 cagcgccgca ggctggcgtt tgaccgggca aagcatcgcc gggcagagat gttagcgcag
     5221 cgtgcgcgtg gcgaagagga agcgcatcat cacagtagcc cggaaggagc aattgaagtc
     5281 gatgaaagcg aagtcgatct cgatgccatc agtgcgcaat ccttgcggct ggtgcgctca
     5341 attttgatgt tgatcgccct gctttcggtc attgtgctgt ggtcagaaat ccattccgct
     5401 ttcggcttcc tcgaaaatat ttcgctgtgg gatgtcactt ccacggtaca gggcgtagaa
     5461 agcctggagc cgattaccct cggtgcggtg ctgattgcca ttctggtgtt tatcatcacc
     5521 acgcagctgg tgcgcaacct gcccgcgctg ctggaactgg cgattctgca gcacctggat
     5581 ttaacgccgg gtacgggcta cgccatcacc accatcacca aatatctgct gatgctaatt
     5641 ggcgggctgg tcggcttctc gatgattggt attgagtggt cgaaattgca gtggctggtc
     5701 gccgcgctcg gtgttggtct cggttttggt ttgcaggaaa ttttcgccaa ctttatctct
     5761 ggcctgatta tcctgttcga aaaaccgatt cgcattggcg atacggtaac gatccgcgat
     5821 cttaccggta gtgtgacgaa aattaacacc cgcgccacca ccatcagcga ctgggaccgc
     5881 aaagaaatta tcgtgccgaa caaggcgttt attaccgagc agtttatcaa ctggtcgctc
     5941 tctgactcgg tcacgcgcgt ggtgttgacg attccggccc ctgccaatgc caacagtgaa
     6001 gaagtgacgg aaatcctgct caccgcagcg cgtcgctgct cgctggtgat cgacaacccg
     6061 gcgccggaag tcttcctggt ggatctgcag caggggattc agattttcga gctgcgtatt
     6121 tacgccgctg agatgggtca ccgtatgccg ctacgccatg agattcacca gctgattctg
     6181 gctggcttcc acgcccacgg tatcgatatg ccattcccgc ccttccagat gcgtctggaa
     6241 agcctgaatg gtaaacaaac ggggagaaca ttaacttctg cgggcaaagg tcgtcaggcg
     6301 ggaagtttgt aaggtctttg tggccggatg aacccatccg gctcacaagc aaaactgata
     6361 gcgcagaaaa aactgccaca accagtagcc gaaaatagcc agcgcggtgg cgtacataaa
     6421 ccagccgcgt ttttttcgcc acaaagcgaa ccagagaaaa gggaaaaaga gcggtaacgt
     6481 cattatcaca ccgacatcgc gagtatcgtc atcttcgaga tacatcaaaa catcacagac
     6541 gttgttaatc ccgcgtccat caatcatcca ctctttgtcc agcgcggagg taatggttat
     6601 ccagaggaac gccacaatga accagatgca gcacaagaca gacatgcgcg cactcatgag
     6661 gtaacccata gtttaatttc gctatagcgc atacgaaatc tcactaattc cctgtcatta
     6721 cgccctatcg tcaggccgac gatagggcat ttgattactc agccacccac tgcggatttt
     6781 ttaccactct gctgcaatag ttctggtaaa tcgccatcgc taacagcgag aagaagacag
     6841 ggccgccaat catccacaat gtgctgtccc agtctccggc ttcaaccaca ggttgaatga
     6901 tggtgaagac gttcgcaaat gtcaccacca gtacgacaac cactgtcgca atcattgccg
     6961 acatacgcgt tttgaaaatc acaaacggtc tgtcgagatc ctgacgtgct ttaaagaacg
     7021 ggaaagccag cgcgaggaac aggtaaggaa gcgtcataga cacgttcgcc atcagcgtca
     7081 gcttgttaaa gaacgccgat gcggtaccgc caccaaacga aaccagcagg atgaagacag
     7141 taaccaaccc acactgcatc cacatggcga tagacggcat ccccatcgca ttcaggcgcg
     7201 tcatcggttc cggccacaat gctttcggcg tcccctggat gatggctttc agcggtgaat
     7261 agcaaagcgt aaagaacgca ccggtataag cgaggaacat cgacagtccg gtaatacgcg
     7321 caaaccatac gcccagcgac aatgacgctt caggtgacaa atgcagtgcg ttacccagcg
     7381 tcaccccgag gctcttcatc agcacatagg taatattgcc gaggttaacg gaaccattac
     7441 ttaatacctg ctgccagttt gtgctgacgc cccataaaaa tattgccagc gaataaccga
     7501 ttgaaataac aatagcggca aaaacaatac ctttggcaaa gttcttttct ggattttccg
     7561 ttttatcaac cagaccacca accgcttcaa ttccgccata ggcaaaaatg gcaaatacca
     7621 caaacgatag cattgccaga ccggactgat aacctgggtt cggtgatgca aggaaattaa
     7681 tatcctgcgc gaaatgccca ccatttaata acaaaatagt aatgcttact aacagcaata
     7741 ctaaattcag acacattact gcaataccgc ccaccgcagt aatgcgggca attttattaa
     7801 tcccttttga agcaacgacg gtgaccagaa tcatccatgc cactgccagc agaccaacca
     7861 cctgcgtagg ctccagtccg gcaatatgcc agtgctgggt catgtcgcta ccgtagagga
     7921 atgttgagaa cggtacccaa actttcgcgg aggtactcac catccagatg atataagagg
     7981 aaaaccacat aaacgtacca atgaaggcaa aacgtggtcc gacactatta ttcatccagg
     8041 aatagatacc gccttcttct ttgcgataag cagctcccat ttcagccatc attaaggcga
     8101 atggaataaa gaataacaat gcagaaaata tataaaagga aatcgcacta taacccatta
     8161 agtaataagc cgatgggcta ttggcaaatc caaatacaga agtaaagatc atcaatatga
     8221 gtcctatcag actcatcttt tttatcgagt gaggcatgaa accatccttc atttcagcgc
     8281 gtgtataaaa cgcgcccact gaactgcact gcccaacatt gagcgggcag cgtaaaaacc
     8341 aatacagaat tgatacctgg atgatatcaa atatccagtc ttaaattgtg gcctttagcg
     8401 gaaaaatgaa aacatatgct acagaatggc gcttatcacg ccattcttcg ctgttaattc
     8461 agtaattttt cagaattatg cccggtcaac gctaaaggcg atgacttcag ccagtgtctc
     8521 cgcgcccagc gccaacatca ccagacgatc aacacctaat gccacgccgg aacagtcagg
     8581 cataccgact ttcaaggctt caatcagatt ctggtcaatg gggtgctgcg gcaaaccgcg
     8641 cgccgcgcgc ttacggttat cttgttcaaa gcgttgttgc tgctcacggg catccgtcaa
     8701 ttcatggaaa ccattcgcca gctcaatacc tttataataa acctcaaagc gttcagcgac
     8761 ccgatgatct tcggtactga tttgcgccag tgatgcctgg ctggctggaa agtggtacac
     8821 aaaggtcggt ttttctttgc caatatttgg ctctacgcca aaggtaaaca gcaattgtag
     8881 aagcgtgtcg cggtcttctt cagtatcggc aacgttgctc aaatccagtt tcgctgccac
     8941 ttcccgcagt tgcgttttgt cggcagagag tgggtcaatt tccagataac gcaagaaagc
     9001 ttgttgataa gaaaggcttt ctgctgccgg acagtccagc acctgttgca agagatcgtc
     9061 cacctcgttc atcaaccggt acatatcata gtgcggtcga taccactcaa gcatagtgaa
     9121 ctcagggttg tgataacgcc ccatctcttc attacggaag ctgcggcaca gctggaatac
     9181 cggcccacaa ccggcaacca gcaggcgctt catatggtat tccgggctgg tcattaacca
     9241 gagattcatc ccctgcgaat gcccggggcc aacgaaacgt gtctcaaacg ggaccaaatg
     9301 aatatcggtt accgtcgcct ggctcataca aggcgtctcc acctccagca ctccacgatc
     9361 ggcaaagaaa cgacggatct ccgccataat cgccgcgcgt tttaataagt taggaatgga
     9421 tgcgctcggc tgccaggatg ccgtttcgct catagttaaa tctccagttt ttgacaaggg
     9481 cacgaagtct actcgcaacg cgacggcgag acaaatttta cgcaggaata acacaacggt
     9541 gggcagtgac taaaaaaagc acgatctgat ggtttagtaa ttaaattaat catcttcagt
     9601 gataatttag ccctcttgcg cactaaaaaa atcgatctcg tcaaatttca gacttatcca
     9661 tcagactata ctgttgtacc tataaaggag cagtggaata gcgttcgcag accgtaactt
     9721 tcaggcactt accctgaagt acggggctgt gggataaaaa caatctggag gaatgtcgtg
     9781 caaacctttc aagccgatct tgccattgta ggcgccggtg gcgcgggatt acgtgctgca
     9841 attgctgccg cgcaggcaaa tccaaatgca aaaatcgcac taatctcaaa agtatacccg
     9901 atgcgtagcc ataccgttgc tgcagaaggg ggctccgccg ctgtcgcgca ggatcatgac
     9961 agcttcgaat atcactttca cgatacagta gcgggtggcg actggttgtg tgagcaggat
    10021 gtcgtggatt atttcgtcca ccactgccca accgaaatga cccaactgga actgtggggg
    10081 tgcccatgga gccgtcgccc ggatggtagc gtcaacgtac gtcgcttcgg cggcatgaaa
    10141 atcgagcgca cctggttcgc cgccgataag accggcttcc atatgctgca cacgctgttc
    10201 cagacctctc tgcaattccc gcagatccag cgtttcgacg aacatttcgt gctggatatt
    10261 ctagttgatg atggtcatgt tcgcggcctg gtagcaatga acatgatgga aggcacgctg
    10321 gtgcagatcc gtgctaacgc ggtcgttatg gctaccggcg gtgcaggtcg cgtttatcgt
    10381 tacaacacca acggcggcat cgttaccggt gacggtatgg gtatggcgct aagccacggc
    10441 gttccgctgc gtgacatgga attcgttcag tatcacccaa ccggtctacc aggttccggt
    10501 atcctgatga ccgaaggctg ccgcggtgaa ggcggtattc tggtcaacaa aaatggctac
    10561 cgttatctgc aagattacgg catgggcccg gaaactccgc tgggcgagcc gaaaaacaaa
    10621 tatatggaac tgggtccacg cgacaaagtt tctcaggcct tctggcacga atggcgtaaa
    10681 ggcaacacca tctccacgcc gcgtggcgat gtggtttatc tcgacctgcg tcaccttggc
    10741 gagaaaaaac tgcatgaacg tttgccgttc atctgcgaac tggcgaaagc gtacgttggc
    10801 gtcgatccgg ttaaagaacc gattccggta cgtccgaccg cacactacac catgggcggt
    10861 atcgaaaccg atcagaactg tgaaacccgc attaaaggtc tgttcgccgt gggtgaatgt
    10921 tcctctgttg gtctgcacgg tgcgaaccgt ctgggctcca actcgctggc ggaactggtg
    10981 gtcttcggtc gtctggccgg tgaacaagcg acagagcgtg cagcaactgc cggtaatggc
    11041 aacgaagcgg caattgaagc gcaggcagct ggcgttgaac aacgtctgaa agatctggtt
    11101 aaccaggatg gcggcgaaaa ctgggctaag atccgcgacg aaatgggcat ggccatggaa
    11161 gaaggctgcg gtatctaccg tacgccggaa ctgatgcaga aaaccatcga caagctggca
    11221 gagctgcagg aacgcttcaa gcgcgtgcgc atcaccgaca cttccagcgt gttcaacacc
    11281 gacctgctct acaccattga gctgggccac ggtctgaacg ttgctgaatg tatggcgcac
    11341 tccgcaatgg cacgtaaaga gtcccgcggc gcgcaccagc gtctggacga aggttgcacc
    11401 gagcgtgacg acgtcaactt cctcaaacac accctcgcct tccgcgatgc tgatggcacg
    11461 actcgcctgg agtacagcga cgtgaagatt actacgctgc cgccagctaa acgtgtttac
    11521 ggtggcgaag cggatgcagc cgataaggcg gaagcagcca ataagaagga gaaggcgaat
    11581 ggctgagatg aaaaacctga aaattgaggt ggtgcgctat aacccggaag tcgataccgc
    11641 accgcatagc gcattctatg aagtgcctta tgacgcaact acctcattac tggatgcgct
    11701 gggctacatc aaagacaacc tggcaccgga cctgagctac cgctggtcct gccgtatggc
    11761 gatttgtggc tcctgcggca tgatggttaa caacgtgcca aaactggcat gtaaaacctt
    11821 cctgcgtgat tacaccgacg gtatgaaggt tgaagcgtta gctaacttcc cgattgaacg
    11881 cgatctggtg gtcgatatga cccacttcat cgaaagtctg gaagcgatca aaccgtacat
    11941 catcggcaac tcccgcaccg cggatcaggg tactaacatc cagaccccgg cgcagatggc
    12001 gaagtatcac cagttctccg gttgcatcaa ctgtggtctg tgctacgccg cgtgcccgca
    12061 gtttggcctg aacccagagt tcatcggtcc ggctgccatt acgctggcgc atcgttataa
    12121 cgaagatagc cgcgaccacg gtaagaagga gcgtatggcg cagttgaaca gccagaacgg
    12181 cgtatggagc tgtactttcg tgggctactg ctccgaagtc tgcccgaaac acgtcgatcc
    12241 ggctgcggcc attcagcagg gcaaagtaga aagttcgaaa gactttctta tcgcgaccct
    12301 gaaaccacgc taaggagtgc aacatgacga ctaaacgtaa accgtatgta cggccaatga
    12361 cgtccacctg gtggaaaaaa ttgccgtttt atcgctttta catgctgcgc gaaggcacgg
    12421 cagttccggc tgtgtggttc agcattgaac tgattttcgg gctgtttgcc ctgaaaaatg
    12481 gcccggaagc ctgggcggga ttcgtcgact ttttacaaaa cccggttatc gtgatcatta
    12541 acctgatcac tctggcggca gccctactgc acaccaaaac ctggtttgag ctggcaccaa
    12601 aagcggccaa tatcattgta aaagacgaaa aaatgggacc agagccaatt atcaaaagtc
    12661 tctgggcggt aactgtggtt gccaccatcg taatcctgtt tgttgccctg tactggtaag
    12721 gagcctgaga tgattaatcc aaatccaaag cgttctgatg aaccggtatt ctggggcctc
    12781 ttcggggccg gtggtatgtg gagcgccatc attgcgccgg tgatgatcct actggttggt
    12841 attctgctac cgctagggct gtttccaggt gatgcgctga gctacgagcg cgttctggcg
    12901 ttcgcgcaga gcttcattgg tcgcgtattc ctgttcctga tgatcgttct gccgctgtgg
    12961 tgtggtttac accgaatgca ccacgcgatg cacgatctga aaatccacgt acctgcgggt
    13021 aaatgggttt tctacggtct ggctgctatc ctgacagttg tcacactgat tggtgtcgtt
    13081 acaatctaac gcatcgccaa tgtaaatccg gcccgcctat ggcgggccgt tttgtatgga
    13141 aaccagaccc tatgttcaaa acgacgctct gcaccttatt aattaccgcc tcttgctcca
    13201 catttgccgc ccctcaacaa atcaacgata ttgtgcatcg cacaattacc ccgcttatag
    13261 agcaacaaag gatccccggt atggcggtag cggtaattta tcagggtaaa ccttattact
    13321 ttacctgggg ctatgcggac atcgccaaaa agcagcccgt cacacagcaa acgttgtttg
    13381 agttaggttc ggtcagcaaa acatttacgg gcgtgcttgg tggcgacgct attgctcgag
    13441 gggaaatcaa gttaagcgat cccacaacaa aatactggcc tgaacttacc gctaaacagt
    13501 ggaatgggat cacactatta catctcgcaa cctacaccgc tggcggcctg ccattgcagg
    13561 tgccggatga ggtgaaatcc tcaagcgact tgctgcgctt ctatcaaaac tggcagcctg
    13621 catgggctcc aggaacacaa cgtctgtatg ccaactccag tatcggtttg ttcggcgcac
    13681 tggctgtgaa gccgtctggt ttgagttttg agcaggcgat gaaaactcgt gtcttccagc
    13741 cactcaaact caatcatacg tggattaatg taccgtccgc agaagaaaag aactacgcct
    13801 ggggatatcg cgaaggtaag gcagtacatg tttcgccagg ggcgttagat gctgaagctt
    13861 atggtgtgaa gtcgaccatt gaagatatgg cccgctgggt gcaaagcaat ttaaaacccc
    13921 ttgatatcaa tgagaaaata cttcaacaag ggatacaact ggcacaatct cgctactggc
    13981 aaaccggcga tatgtatcag ggtctgggct gggaaatgct ggactggccg gtaaatcctg
    14041 acatcatcat taacggcagt gacaataaaa ttgcactggc agcacgcccc gtaaaaccga
    14101 ttacgccccc aactcctgca gtacgcgcat catgggtaca taaaacgggg gcgaccggcg
    14161 gatttggtag ctatgtcgcg tttattccag aaaaagagct gggtatcgtg atgctggcta
    14221 acaaaaacta tcccaatcca gcgagagtta ccgccgcctg gcagattctc aacactctac
    14281 agtaaaattt catcgggtcc gaattttcgg accttttctc cgcttttcct tgctgtcatc
    14341 tacacttaga aaaaaaccag taaggaaaca tttatgcgcc tgctccctct cgttgccgca
    14401 gcgacagctg catttctggt cgttgcctgc agttctccta caccgccgcg tggcgtgacc
    14461 gtagtgaata atttcgacgc taaacgctat ctcggcacct ggtatgagat tgcccgtttt
    14521 gatcaccgct ttgaacgtgg actggaaaaa gtcaccgcaa catacagcct gcgtgatgac
    14581 ggcggcctga atgtcattaa taaaggctat aaccctgaca gagaaatgtg gcagcagagt
    14641 gaagggaaag cgtactttac cggcgcacca actcgcgctg cgctgaaagt gtcattcttt
    14701 ggtcctttct atggcggtta taacgttatt gcactcgatc gggaataccg ccatgcgctg
    14761 gtttgcggcc cggaccgcga ctacctgtgg atactctccc gcacgccaac catttctgac
    14821 gaagtgaaac aggagatgct ggcagtcgcg acccgggaag ggtttgatgt cagtaagttt
    14881 atttgggtac agcagcccgg tagttaatga gtgctgagtt tcagaccaat aatccccaat
    14941 acgattaacg ccagactcgc cagacgcatc gggttagcgg actcaccgag caacacaatg
    15001 ccggtgatgg ccgcgccgac tgcgccaata cccgtccaca cggcataagc cgtccctact
    15061 ggtaacgatt tcatcgccca ggcaagtagc gccatactga caatcatcgc cgtcacggta
    15121 ataacacttg gcgtcaaacg actaaagccg tgggtatatt tcaggccaac ggcccatacc
    15181 acttccagca gaccagcaat aactaagata atccaggaca tatcaggctc cggaaaattg
    15241 gggccgtccc cggtgaaaag acgcgtttgc aggtcgtcct gcaaagctga tggttgaacg
    15301 gatattttgc caggtggcag gggaatttca actattacct atgtaactat cgcagaaaaa
    15361 acaaacggca cgacacagct gtcgtaccgt tattgcttat tgctgcgctt tcgttgctgc
    15421 gccagaaatc gcgttaccgc catcagaaat gtcttcacca acgccacgcg tggtgttgca
    15481 ggcagttaat actgttgaaa gcaccagaac agaaaagatc gctgcaattg tcttcttcac
    15541 cataacgtct tccttttagg taatgttatt tatgtttgcc tatagcaaat taataataga
    15601 caacatcgcc aaaaatgacg gaaatctgat gatttttcgg aagagaagaa aaattagctg
    15661 gcagcgcggg agatggagtt gccgaggtgt ttgatatctt cgccgaaacc tcgagcggtg
    15721 ttacagcccg taagcagcgt gctggcaagc aaaacaagaa cgataaggcg tttcatcatc
    15781 tctaacctga ataagtgatg gtgcagcctg caggccgcac cacaaccgca ttacttcacg
    15841 cgagagacgt attcaccaga gcgggtatcc actttgatga cttcgccgat ttgtacaaac
    15901 agcggaactt taaccacagc gccagtagac agggtagccg gtttgccgcc agtacctgcg
    15961 gtatcacctt tcaggcccgg atcggtatcc acgatttcca gttcaacgaa gttcggcgga
    16021 gtaacggaga tcggctgacc attccacaga gttacgatac actctgcctg atccagcaac
    16081 catttggcgt tgtcgccaat tgcttttgca tcagcagaca gctgctcgaa agtttcgttg
    16141 ttcatgaagt gccagaactc accgtcgttg tacaggtaag tcaggttcat atcgacaaca
    16201 tcagcacctt cagcggaatc agtagatttg aaggtttttt ctacgcgagt accggtcagc
    16261 agacgacgca gtttaacgcg agcaaatgcc tggcctttac ccggttttac gaattcactc
    16321 gcttcaaccg cgtaaggttc gccgtctaac atgattttaa gaccagcacg aaaatcgttg
    16381 ctatagtacg ttgccataag gccctctgaa atttgttaat tggtagctaa gccacaaaat
    16441 ggcgcatatt gtaaccctaa ataccccatc cagagaagat tggttaacgc aacttgccga
    16501 tgttgtgacc gatcctgatg aacttctgcg tcttttgaat atagacgcgg acgaaaaact
    16561 gttggccgga cgcagcgcca aaaagctgtt tgccctgcgt gtgccccgct catttatcga
    16621 tcgcatggag aaaggcaatc cgaacgatcc gcttttgcgt caggtaatta cctcgcaaga
    16681 tgagtttgtt gtcgcgcccg gattctccac cgacccgctg gaagaacagc acagcgtagt
    16741 gccaggtttg ttgcataaat accacaaccg ggcgcttttg ctggtcaaag gcggctgcgc
    16801 ggtaaattgc cgctattgct tccgtcgcca cttcccctat gccgaaaatc agggcaacaa
    16861 gcgtaactgg cagactgcac ttgagtatgt tgctgcgcat ccggaactgg acgagatgat
    16921 tttctccggc ggcgatccgc tgatggcgaa agatcacgag ctggactggt tgctcacaca
    16981 actggaagcc atcccgcata tcaaacgtct gcggattcac agccgtctgc cgattgtgat
    17041 cccggcacgc atcacagatg cgctggttga acgcttttct cattctacgc tgcaaatctt
    17101 gctggtgaat cacattaacc atgccaatga ggtagatgaa acattccgtc aggcgatggc
    17161 taagttgcgc cgggtaggcg ttactttgct gaaccagagc gttctgttac gtggtgtgaa
    17221 cgataacgcg caaacgctgg caaacctgag taatgcgttg ttcgatgcgg gtgtgatgcc
    17281 gtattacctg catgtgctcg ataaagtaca gggcgcggcg cattttatgg tgagtgatga
    17341 cgaagcacgg cagattatgc gtgagttgct gacactggtg tcgggatatc tggtgcctaa
    17401 actggcgcga gaaattggcg gcgaacccag caaaacaccg ctggatctcc agctacgcca
    17461 gcagtaactg attaaacagg gaagtttaat ctttgcccgt tgcataacct ttaattattc
    17521 atatacattg ctgttattac tatttatata accgacacca ataattaacc tttcttttct
    17581 gtttatatag agtgagcacg gctatttatg ttattttaac aactattact accaagccca
    17641 tttatctggc ttataaacta aaattaatta tttaattgag aaatggttag ggagaaccta
    17701 catggccata agcatcaagg gtgttaatac cggtgttatt cgcaagagta ataatttcat
    17761 tgcactggcg ctgaaaatta aagaacctcg caataaagaa tcgttgttct ttatgtctgc
    17821 catggaattg cgcgaccttc tgattgcgct ggaaagtcgt ctgcatcaaa agcataaact
    17881 ggatgctgct gcacgccttc agtatgaaca agctcgcgat aaagtcatta agaaaatggc
    17941 agaaaatatc ccagaaattc tggttgatga gcttaaaaat gccgatatta atcgtcgggt
    18001 taacacgctg gaacttaccg atgatcaggg cgaaaatctt accttcgtat taacactaca
    18061 tgacggtagc aaatgtgagt tagtcgtcaa tgagttgcag attgaaatgc tggcgcgagc
    18121 aatcattcat gcaattaata atgcggaaat gcgtgaactg gcattacgta ttacctcact
    18181 gttagatttc ctgccgttat atgatgtcga ctgccaggat gatggtaatc tggaatatga
    18241 cacctattcc caaccggaat ggaaacataa cttgttcaac cattatctgg cggtgcttta
    18301 ccgctttaaa gatgaaagtg gcaaagaaca atttagcggc gcagtggtga aaacgcgtga
    18361 agcaacgccg ggtaaagaag tggaggcgat cactcgccga atgcttgatt tcagcccccg
    18421 actgaaaaaa ctcgcgggtg tgccatgtca ggtctatgtt cgcaccgtag cggcaaataa
    18481 cgcccaaccg ctaacccagg atcaatgctt acgcgcgctg catcacttac gtgttcaatc
    18541 caccagcaaa actgcaccac aggcgaaata atcttatctg ttttactacg aggctggaag
    18601 tatccagcct ctggatcaca tcagttcggg cacttataaa cctgaccgat aatctggcta
    18661 tccgtcggga caaaactgga caacattccc tgcgacgggc tgctgatgcc ataaatcacg
    18721 ttaccgccca ttgcagccgc ctggttgcgc agatcgtttg ctgcgccgcg catagaaccg
    18781 ccttcttctc cgtgttgccc ggaaagccag ttgctttgct tacctgttgc agtaccaatc
    18841 agctggcact ctgcacctgg ttgctcgtcc acaatgcgta cactctgacc ggcagcactc
    18901 aattcgttgc tggagctaca acccgccatc agtagcgcgg caccgacaat ccctgctaag
    18961 tattttacgt gcatgttatt ccccataatc aatgagctgg acgccactcg cgtcgtccgt
    19021 gtctgaatct tatactagaa agatgaccaa aagaaaaacc cccagacatt tctgcccggg
    19081 ggtttgttta tttctgcgag gtgcagggca attacatcat gccgcccatg ccacccatgc
    19141 cgcccatacc gccagcagcg cctaagtcag ctgcatcgtt tttcggcagg tcggtaacca
    19201 tgcactcggt ggtgatcatc aggccagcca cagaagccgc gtactgcaga gcagaacggg
    19261 ttactttggt tggatccagg atacccatat cgatcatgtt gccgtattct tcagttgctg
    19321 cgttgtaacc gtagttgccg tcgccgcctt taacggtgtt agcaacaaca gacggttctt
    19381 cgccgcagtt caggacgatc tgacgcagcg gagcttccat tgcacgcagt gcaactttga
    19441 tacccacgtt ctggtcttcg ttctgaccac gcaggtcagc cagtttagac gctacgcgga
    19501 tcagcgcaac accaccacca gcaaccacgc cttcttctac cgcagcacgg gtcgcgtgca
    19561 gggcgtcttc aacgcgtgct tttttctctt tcatttcaac ttcggtagca gcaccaactt
    19621 tgataactgc aacgccgcct gccagtttcg ctacgcgctc ctgcagtttt tcacggtcgt
    19681 agtcagaagt tgcttcttca atctgctgac ggatctgagc aacacggccc tggattgcag
    19741 cttcttcacc cacgccatcg atgatggtgg tggtgtcttt gttgatcaca acacgtttag
    19801 cctgacccag gtcttccagg gttgcttttt ccagctccat accgatctct tcagagatta
    19861 cggtaccgcc agtcagggtt gcgatatcct gcagcatagc tttacgacga tcgccgaagc
    19921 ccggagcttt aaccgcagca actttcacga tgccacgcat ggtgttaaca accagagttg
    19981 ccagtgcttc gccttcaaca tcttcagcga tgatcagcag cggtttacct gctttggcaa
    20041 cagcttccag aaccggcagc atttcgcgga tgttggagat tttcttgtca gccagcagga
    20101 tgaacgggct ttccagttct actgcgccag tttccggctt gttgatgaag taaggagaca
    20161 agtagccacg gtcgaactgc ataccttcaa ccacgtccag ttcgtcctgc agaccggtac
    20221 cgtcttcaac ggtgataacg ccttctttac cgactttgtc catcgcttca gcgatcagtt
    20281 tacctacggt ttcgtcggag ttagcagaga tggtaccaac ctgagcaatc gctttagagt
    20341 cagagcacgg tacggacagc gctttcagtt cttcaactgc agcggtaaca gctttgtcga
    20401 taccacgttt caggtccatc gggttcatgc ccgcagcaac agctttcaga ccctcagtga
    20461 tgatagcctg agccagtacg gttgcagtgg tggtaccgtc gcctgcagcg tcattcgctt
    20521 tagaggcaac ttctttcacc atctgcgcac ccatattttc gaacttgtct tccagttcga
    20581 tttcacgagc aacggaaaca ccatctttgg tgatggtcgg tgcaccgaaa gatttatcca
    20641 gaactacgtt acggccttta ggaccgaggg taactttcac tgcatctgcc agtacgttta
    20701 cgccgcgcag cattttcaca cgagcgtcgt taccgaattt tacgtcttta gctgccatta
    20761 tctttattcc ttaaattcgt atgttcagtg tcgtgcgcgg attacgcttc aacaattgcc
    20821 agaatgtcgc tttcggacat gatcaacact tcttcattgt cgatcttctc agatttcaca
    20881 ccgtagccat cgttgaaaat aacgatgtcg ccaactttca catccagcgg cttcacttcg
    20941 ccattttcaa ggatacggcc attgccgaca gccagcactt cgccgcgggt ggatttagcc
    21001 gctgcagagc cggtcagaac gatgccgcca gcagatttag tttcaacttc tttacgcttg
    21061 acgatcacgc gatcatgcaa tggacgaata ttcattgata actctccttt gagaaagtcc
    21121 gtatctgtta tgggtgacgc cggagcttac gtggtttccc ggctggtgac cagagaaatg
    21181 gggatgaggc ttcgcccctt caagggggaa aaagaaaaaa aattctgatc agcacaaaat
    21241 cgggtgaaaa ccctgattca cctcacattt catcgctatt tcttcatcac cgtcataagc
    21301 aaatctgatt gtgctaccat cgaaaatcta cgcagttgcc caaaatttgg gcgcaatcgg
    21361 acatcaaccc atgagtggac tcaaacaaga actggggctg gcccagggca tcggcctgct
    21421 atcgacgtca ttattaggca ctggcgtgtt tgccgttcct gcgttagctg cgctagtagc
    21481 aggcaataac agcctgtggg cgtggcccgt tttgattatc ttagtgttcc cgattgcgat
    21541 tgtgtttgcg attctgggtc gccactatcc cagcgcaggc ggcgtcgcgc acttcgtcgg
    21601 tatggcgttt ggttcgcggc ttgagcgagt caccggctgg ttgtttttat cggtcattcc
    21661 cgtgggtttg cctgccgcgc tacaaattgc tgccggattc ggtcaggcaa tgtttggctg
    21721 gcatagctgg caactgttgt tggcagaact cggtacgctg gcgctggtgt ggtatatcgg
    21781 tactcgcggt gccagttcca gtgctaatct acaaacagtt attgccggac ttatcgtcgc
    21841 actgattgtc gctatctggt gggcgggcga tatcaaacct gcgaatatcc ccttccctgc
    21901 gccaggaaat atcgaactta ccgggttatt tgctgcgtta tcagtgatgt tctggtgttt
    21961 tgtcggtctg gaagcatttg cccatcttgc ctcggaattt aaaaatccag agcgtgattt
    22021 tcctcgtgct ttgatgattg gcctgctgct ggcaggatta gtctattggg gctgtacggt
    22081 agtcgtctta cacttcgacg cctatggtga acaaatggcg gcggcagcat cgcttcccaa
    22141 aattgtagtg cagttgttcg gtgtaggagc gttatggatt gcctgcgtaa ttggctatct
    22201 ggcctgcttt gccagtctca acatttatat acagagcttc gcccgcctgg tctggtcgca
    22261 ggcgcaacat aatcctgacc actacctggc acgcctctct tctcgccata tcccgaataa
    22321 tgccctcaat gcggtgctcg gctgctgcgt ggtaagcacg ttggtgattc atgctttaga
    22381 gatcaatctg gacgctctta ttatttatgc caatggcatc tttattatga tttatctgtt
    22441 atgcatgctg gcaggctgta aattattgca aggacgttat cgactactgg cggtggttgg
    22501 cgggctatta tgcgttctgt tactggcaat ggtcggctgg aaaagtctct acgcgctgat
    22561 catgctggcg gggttatggc tgtttctgcc aaaacgaaaa acgccggaaa atggcataac
    22621 cacataatcc ggcgtttcga cattaatcct ggcgatcgtc tttatgatca aggcggtcgc
    22681 ggtcatcatc ctttcgctgg tactcaccat caaaagtatt accgccaccg gtcccggcgc
    22741 taaaaccgcc gcctggcatg cgagaaaagc gcaaatgcgg catcaacttc actgtcagat
    22801 gcttttgcac cggcggcaat aaaagcagaa gaccgaggaa gtcggtgaaa aagcccggta
    22861 ataaaagcag caaaccggca atgatcagcg aaacactttt aatcatctcc gccgctgggt
    22921 tttcacccgc cgccattttt tgctgcatca gcacgaaatt cttaaagccc tggttacgta
    22981 ccagtgacat accgataact gacgtgaata taaccagcac gagggtcagc aataccccca
    23041 atacatgagc aacctgaata aagattgaaa tctcaatata gacataaagg aaaatggcaa
    23101 taaaaggtaa ccagcgcaaa ggtttctcct gtaatagcag ccggttaaac ccggctacct
    23161 gaatgggttg cgaatcgcgt ttagcttata ttgtggtcat tagcaaaatt tcaagatgtt
    23221 tgcgcaacta tttttggtag taatcccaaa gcggtgatcc atttcacaaa ttaataatta
    23281 aggggtaaaa accgacactt aaagtgatcc aggttacggt agaaatcctc aagcagcata
    23341 tgatctcggg tattcggtcg atgcagggga taatcgtcgg tcgaaaaaca ttcgaaacca
    23401 catatattct gtgtgtttaa agcaaatcat tggcagcttg aaaaagaagg ttcacatgtc
    23461 aaacaacatt cgtatcgaag aagatctgtt gggtaccagg gaagttccag ctgatgccta
    23521 ctatggtgtt cacactctga gagcgattga aaacttctat atcagcaaca acaaaatcag
    23581 tgatattcct gaatttgttc gcggtatggt aatggttaaa aaagccgcag ctatggcaaa
    23641 caaagagctg caaaccattc ctaaaagtgt agcgaatgcc atcattgccg catgtgatga
    23701 agtcctgaac aacggaaaat gcatggatca gttcccggta gacgtctacc agggcggcgc
    23761 aggtacttcc gtaaacatga acaccaacga agtgctggcc aatatcggtc tggaactgat
    23821 gggtcaccag aaaggtgaat atcagtacct gaacccgaac gaccatgtta acaaatgtca
    23881 gtctactaac gacgcctacc cgaccggttt ccgtatcgca gtttactctt ccctgattaa
    23941 actggtagat gcgattaacc aactgcgtga aggctttgaa cgtaaagctg tcgaattcca
    24001 ggacatcctg aaaatgggtc gtacccagct gcaggacgca gtaccgatga ccctcggtca
    24061 ggaattccgc gctttcagca tcctgctgaa agaagaagtg aaaaacatcc aacgtaccgc
    24121 tgaactgctg ctggaagtta accttggcgc aacagcaatc ggtactggtc tgaacacgcc
    24181 gaaagagtac tctccgctgg cagtgaaaaa actggctgaa gtcactggct tcccatgcgt
    24241 accggctgaa gacctgatcg aagcgacctc cgactgcggc gcttatgtta tggttcacgg
    24301 cgcgctgaaa cgcctggctg tgaagatgtc caaaatctgt aacgacctgc gcttgctctc
    24361 ttctggtcca cgtgccggcc tgaacgagat caacctgccg gaactgcagg caggctcttc
    24421 catcatgcca gctaaagtaa acccggttgt tccggaagtg gttaaccagg tatgcttcaa
    24481 agtcatcggt aacgacacca ctgttaccat ggcagcagaa gcaggtcagc tgcagttgaa
    24541 cgttatggag ccagtcattg gccaggccat gttcgaatcc gttcacattc tgaccaacgc
    24601 ttgctacaac ctgctggaaa aatgcattaa cggcatcact gctaacaaag aagtgtgcga
    24661 aggttacgtt tacaactcta tcggtatcgt tacttacctg aacccgttca tcggtcacca
    24721 caacggtgac atcgtgggta aaatctgtgc cgaaaccggt aagagtgtac gtgaagtcgt
    24781 tctggaacgc ggtctgttga ctgaagcgga acttgacgat attttctccg tacagaatct
    24841 gatgcacccg gcttacaaag caaaacgcta tactgatgaa agcgaacagt aatcgtacag
    24901 ggtagtacaa ataaagaagg cacgtcagat ggcgtgcctt ttttcttgtg agcagtaact
    24961 taaaaataac aatttaatat caacttgtta aaaaacaagg aaggctaata tgctagttgt
    25021 agaactcatc atagttttgc tggcgatctt cttgggcgcc agattggggg gaataggtat
    25081 tggttttgca ggcggattgg gggtgctggt tcttgccgct attggcgtta aacccggtaa
    25141 catcccgttc gatgtcattt ccattatcat ggcggttatc gccgctattt ctgccatgca
    25201 ggttgctggc ggtctggact atctggttca tcagacagaa aagctgctgc gccgtaaccc
    25261 gaaatacatc acgatcctcg caccgatcgt gacctatttc ctgactatct ttgctggtac
    25321 tggcaacatc tctctggcga cactgccagt tatcgctgaa gttgcgaagg aacaaggcgt
    25381 taaaccttgc cgtccgctgt ctactgcagt ggtatccgcg cagattgcga tcaccgcatc
    25441 gccaatctca gcggcagtgg tttacatgtc ttccgtgatg gaaggtcatg gcatcagcta
    25501 cctccatctg ctctccgtgg tcatcccgtc caccctgctg gcggttctgg tgatgtcctt
    25561 cctggtcact atgctgttca actccaaact ctctgacgat ccgatttatc gcaagcgtct
    25621 ggaagagggc ctggttgaac tgcgcggtga aaagcagatt gaaatcaaat ccggtgcaaa
    25681 aacgtccgtc tggctgttcc tgctgggcgt agttggcgtg gttatctatg caatcatcaa
    25741 cagcccaagc atgggtctgg ttgaaaaacc actgatgaac accaccaacg caatcctgat
    25801 catcatgctc agcgttgcaa ctctgaccac cgttatctgt aaagtcgata ccgacaacat
    25861 tctcaactcc agcaccttca aagcaggtat gagcgcctgt atttgtatcc tgggtgttgc
    25921 gtggctgggc gatactttcg tttccaacaa catcgactgg atcaaagata ccgctggtga
    25981 agtgattcag ggtcatccgt ggctgctggc cgtcatcttc ttctttgctt ctgctctgct
    26041 gtactctcag gctgcaaccg caaaagcact gatgccgatg gctctggcac tgaacgtttc
    26101 tccgctgacc gctgttgctt cttttgctgc ggtgtctggt ctgttcattc tgccgaccta
    26161 cccgacgctg gttgctgcgg tacagatgga tgacacgggt actacccgta tcggtaaatt
    26221 cgtcttcaac catccgttct tcatcccggg tactctgggt gttgccctgg ccgtttgctt
    26281 cggcttcgtg ctgggtagct tcatgctgta atgacccatc gcggggcgtt cacgccccgc
    26341 tttctttccc gccgactaac atcctttccc cgtccgttgt atagtgacct ctctcttgca
    26401 gttccatctg ttcttgcgag gtgtttatgc ttgatgaaaa aagttcgaat accacgtctg
    26461 tcgtggtgct atgtacggca ccggatgaag cgacagccca ggatttagcc gccaaagtgc
    26521 tggcggaaaa actggcggcc tgcgcgacct tgatccccgg cgctacctct ctctattact
    26581 gggaaggtaa gctggagcaa gaatacgaag tgcagatgat tttaaaaact accgtatctc
    26641 accagcaggc actgctggaa tgcctgaagt ctcatcatcc atatcaaacc ccggaacttc
    26701 tggttttacc tgttacacac ggagacacag attacctctc atggctcaac gcatctttac
    26761 gctgatcctg ctactttgca gcacttccgt ttttgccgga ttattcgacg cgccgggacg
    26821 ttcacaattt gtccccgcgg atcaagcctt tgcttttgat tttcagcaaa accaacatga
    26881 ccttaatctg acctggcaga tcaaagacgg ttactacctc taccgtaaac agatccgcat
    26941 tacgccggaa cacgcgaaaa ttgctgacgt gcagctgccg caaggcgtct ggcatgaaga
    27001 tgagttttac ggcaaaagcg agatttaccg cgatcggctg acgcttcccg taaccatcaa
    27061 ccaggcaagt gcgggagcaa cgttaactgt cacctaccag ggctgtgctg atgccggttt
    27121 ctgttatccg ccagaaacca aaaccgttcc gttaagcgaa gtggtcgcca acaacgaagc
    27181 gtcacagcct gtgtctgttc cgcagcaaga gcagcccacc gcgcaattgc ccttttccgc
    27241 gctctgggcg ttgttgatcg gtattggtat cgcctttacg ccatgcgtgc tgccaatgta
    27301 cccactgatt tctggcatcg tgctgggcgg taaacagcgg ctttccactg ccagagcatt
    27361 gttgctgacc tttatttatg tgcaggggat ggcgctgact tacacggcgc tgggtctggt
    27421 ggttgccgcc gcagggttac agttccaggc ggcgctacag cacccatacg tgctcattgg
    27481 cctcgccatc gtctttacct tgctggcgat gtcaatgttt ggcttgttta ctctgcaact
    27541 cccctcttcg ctgcaaacac gtctcacgct gatgagcaat cgccaacagg gcggctcacc
    27601 tggcggtgtg tttattatgg gggcgattgc cggactgatc tgttcaccat gcaccactgc
    27661 accgcttagc gcgattctgc tgtatatcgc ccaaagcggg aacatgtggc tgggcggcgg
    27721 cacgctttat ctttatgcgc tgggcatggg cctgccgctg atgctaatta ccgtctttgg
    27781 taaccgcttg ctgccgaaaa gcggcccgtg gatggaacaa gtcaaaaccg cgtttggttt
    27841 tgtgatcctc gcactgccgg tcttcctgct ggagcgagtg attggtgata tatggggatt
    27901 acgcttgtgg tcggcgcttg gtgtcgcatt ctttggctgg gcctttatca ccagcctaca
    27961 ggccaaacgc ggctggatgc gcgtggtgca aataatcctg ctggcagcgg cattggttag
    28021 cgtacgccca cttcaggatt gggcatttgg tgcaacacat accgcgcaaa ctcagacgca
    28081 tctcaacttt acacaaatca aaacggtaga tgagttaaat caggcgctcg ttgaagccaa
    28141 aggcaaacca gtgatgttag atctctatgc cgactggtgc gtcgcctgta aagagtttga
    28201 gaaatacacc ttcagcgact cgcaggtgca aaaagcgtta gcagatacgg tcttacttca
    28261 ggccaacgtc actgccaacg acgcacaaga tgtggcgctg ttaaagcatc ttaatgtcct
    28321 tggcctaccg acaattctct tttttgacgg acaaggccag gagcatccac aagcacgcgt
    28381 cacgggcttt atggatgctg aaaccttcag cgcacatttg cgcgatcgcc aaccgtgaac
    28441 gacacttgca gtgggaaaga cggaggaaaa tagcgtgcaa cgtgaagatg tactgggaga
    28501 agccctgaaa ttattagaat tacaagggat tgccaacacc acgctggaga tggttgctga
    28561 acgtgtggat tatccactgg acgagctacg ccgcttctgg ccagacaaag aggcaatcct
    28621 ctacgatgcg ctgcgttatc ttagccaaca gatagatgtc tggcgtcgtc agctgatgct
    28681 ggacgaaacg caaaccgccg aacaaaagtt gctggcacgt tatcaggcgt tatcggagtg
    28741 cgttaaaaac aaccgctatc cgggctgtct gtttatcgct gcctgtacgt tttatcccga
    28801 tcctggccac cctattcatc aactggccga tcagcaaaaa agcgcggcct acgatttcac
    28861 ccacgaactg ttaaccacgc tggaagttga cgatccggcg atggtagcaa agcagatgga
    28921 actggtgctg gaaggctgtt taagccgaat gctggtgaat cgtagccagg cggatgtcga
    28981 caccgcacat cggctggcgg aagatatcct gcgcttcgcc cgctgccgtc agggtggtgc
    29041 actgacctga cagaaacaca gaaaagaagc gatttgccgc aatcttaagc agttgaatcg
    29101 cttttactga aattaggttg acgagatgtg cagattacgg tttaatgcgc cccgttgccc
    29161 ggatagctca gtcggtagag caggggattg aaaatccccg tgtccttggt tcgattccga
    29221 gtccgggcac caaattcata tcaacggacc tccacggagg tccgtttttc gtttcagaac
    29281 gccacaattt aagcgttcta cctacaaatc aattctaccg aactcaacca gattc
//
LOCUS       DAFGPF010000059        28223 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFGPF010000059 DAFGPF010000000
VERSION     DAFGPF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28223
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.059"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..299)
                     /gene="tuf"
                     /locus_tag="LSX49_002842"
     CDS             complement(<1..299)
                     /gene="tuf"
                     /locus_tag="LSX49_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL7169231.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQM"
     gene            complement(370..2484)
                     /gene="fusA"
                     /locus_tag="LSX49_002843"
     CDS             complement(370..2484)
                     /gene="fusA"
                     /locus_tag="LSX49_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL7169232.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2581..3051)
                     /gene="rpsG"
                     /locus_tag="LSX49_002844"
     CDS             complement(2581..3051)
                     /gene="rpsG"
                     /locus_tag="LSX49_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBL7169233.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="LSX49_002845"
     CDS             complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="LSX49_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBL7169234.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="LSX49_002846"
     CDS             complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="LSX49_002846"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HBL7169235.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYL
                     ESLRNAPIKVYALNEDLIARGLTGRISNDIIPIDYTDFVRLTVKHSSQMAW"
     gene            complement(3942..4301)
                     /gene="tusC"
                     /locus_tag="LSX49_002847"
     CDS             complement(3942..4301)
                     /gene="tusC"
                     /locus_tag="LSX49_002847"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HBL7169236.1"
                     /translation="MKRIAFVFSTAPHGTTAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWICAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4301..4687)
                     /gene="tusD"
                     /locus_tag="LSX49_002848"
     CDS             complement(4301..4687)
                     /gene="tusD"
                     /locus_tag="LSX49_002848"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HBL7169237.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSSVFFYREGV
                     YNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSN
                     LQPGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4687..5409)
                     /locus_tag="LSX49_002849"
     CDS             complement(4687..5409)
                     /locus_tag="LSX49_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL7169238.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5576..6388)
                     /gene="fkpA"
                     /locus_tag="LSX49_002850"
     CDS             complement(5576..6388)
                     /gene="fkpA"
                     /locus_tag="LSX49_002850"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL7169239.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATTADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6609..6827
                     /locus_tag="LSX49_002851"
     CDS             6609..6827
                     /locus_tag="LSX49_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HBL7169240.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6876..7466)
                     /gene="slyD"
                     /locus_tag="LSX49_002852"
     CDS             complement(6876..7466)
                     /gene="slyD"
                     /locus_tag="LSX49_002852"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL7169241.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7561..7761)
                     /locus_tag="LSX49_002853"
     CDS             complement(7561..7761)
                     /locus_tag="LSX49_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HBL7169242.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7771..9576)
                     /gene="kefB"
                     /locus_tag="LSX49_002854"
     CDS             complement(7771..9576)
                     /gene="kefB"
                     /locus_tag="LSX49_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HBL7169243.1"
                     /translation="MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALL
                     AGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFT
                     AATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFI
                     SVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGG
                     EFAFVLFSSASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDE
                     KPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGD
                     ATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELL
                     QAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADT
                     VQISRAREARRELEEIFQREMQQERRQLDGWDEFE"
     gene            complement(9576..10127)
                     /gene="kefG"
                     /locus_tag="LSX49_002855"
     CDS             complement(9576..10127)
                     /gene="kefG"
                     /locus_tag="LSX49_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HBL7169244.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10258..12171
                     /locus_tag="LSX49_002856"
     CDS             10258..12171
                     /locus_tag="LSX49_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7169245.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGQAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADE
                     SPIQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEPF
                     DGDLEDYQQWLSDVQKQENQADEAPKENANSAQARKDQKRREAELRAQTQPLRKEIAR
                     LEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQ
                     EQLEQMLLEGQSN"
     gene            12171..13193
                     /locus_tag="LSX49_002857"
     CDS             12171..13193
                     /locus_tag="LSX49_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL7169246.1"
                     /translation="MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFT
                     PHWHRLELPDGDFVDLAWSEDPAQARHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGNDLPIDAAVIVSAPFMLEACSYHMEKGFSRIYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            13187..13405
                     /locus_tag="LSX49_002858"
     CDS             13187..13405
                     /locus_tag="LSX49_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HBL7169247.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            13459..14328
                     /locus_tag="LSX49_002859"
     CDS             13459..14328
                     /locus_tag="LSX49_002859"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HBL7169248.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQSLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(14383..14787)
                     /locus_tag="LSX49_002860"
     CDS             complement(14383..14787)
                     /locus_tag="LSX49_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HBL7169249.1"
                     /translation="MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            15089..15721
                     /gene="crp"
                     /locus_tag="LSX49_002861"
     CDS             15089..15721
                     /gene="crp"
                     /locus_tag="LSX49_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HBL7169250.1"
                     /translation="MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            15772..17862
                     /locus_tag="LSX49_002862"
     CDS             15772..17862
                     /locus_tag="LSX49_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL7169251.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQVLLAKDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQDAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(17929..19149)
                     /gene="argD/dapC"
                     /locus_tag="LSX49_002863"
     CDS             complement(17929..19149)
                     /gene="argD/dapC"
                     /locus_tag="LSX49_002863"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HBL7169252.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQYKGRARDFLYAGAEEGVMVLNAGPDVMRFAPSLVVEDADIDEG
                     MHRFAHAVAKVVGA"
     gene            complement(19235..19798)
                     /gene="pabA"
                     /locus_tag="LSX49_002864"
     CDS             complement(19235..19798)
                     /gene="pabA"
                     /locus_tag="LSX49_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HBL7169253.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHNGVGVFKGLANPLTVTRYHSLVVEPDSLPECFEVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(19830..20432)
                     /locus_tag="LSX49_002865"
     CDS             complement(19830..20432)
                     /locus_tag="LSX49_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HBL7169254.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNKLNIRQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYLEKEGNAL
                     MQDLEEEKYLTSLEKDKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQNGAMGDLTALQMIFSKVVSEVGESE"
     gene            complement(20422..20589)
                     /locus_tag="LSX49_002866"
     CDS             complement(20422..20589)
                     /locus_tag="LSX49_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HBL7169255.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEALRRHYER"
     gene            complement(20694..21266)
                     /gene="ppiA"
                     /locus_tag="LSX49_002867"
                     /gene_synonym="rotA"
     CDS             complement(20694..21266)
                     /gene="ppiA"
                     /locus_tag="LSX49_002867"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HBL7169256.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            21537..22718
                     /gene="tsgA"
                     /locus_tag="LSX49_002868"
     CDS             21537..22718
                     /gene="tsgA"
                     /locus_tag="LSX49_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HBL7169257.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
     gene            22980..25523
                     /gene="nirB"
                     /locus_tag="LSX49_002869"
     CDS             22980..25523
                     /gene="nirB"
                     /locus_tag="LSX49_002869"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HBL7169258.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVVCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            25520..25846
                     /gene="nirD"
                     /locus_tag="LSX49_002870"
     CDS             25520..25846
                     /gene="nirD"
                     /locus_tag="LSX49_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HBL7169259.1"
                     /translation="MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYDARVKDG
                     VVQLRG"
     gene            25973..26779
                     /gene="nirC"
                     /locus_tag="LSX49_002871"
     CDS             25973..26779
                     /gene="nirC"
                     /locus_tag="LSX49_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HBL7169260.1"
                     /translation="MFTDTITKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGTISHGQMW
                     AILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
                     NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYT
                     LAGIGHNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            26798..28171
                     /gene="cobA"
                     /locus_tag="LSX49_002872"
     CDS             26798..28171
                     /gene="cobA"
                     /locus_tag="LSX49_002872"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBL7169261.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEYGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
BASE COUNT         6816 a         7558 c         7141 g         6708 t
ORIGIN      
        1 tccatctgag cagcaccggt gatcatgttt ttaacatagt cggcgtgccc cgggcagtct
       61 acgtgtgcgt agtgacgggt cggggtgtcg tattcaacgt gagaagtgtt gatggtgata
      121 ccacgagcct tttcttccgg cgcgttatcg atctggtcga atgcacgagc agcaccgccg
      181 taggttttag ccagtacggt ggtgattgca gcggtcagag tagttttacc gtggtcaacg
      241 tggccgatag taccaacgtt aacgtgcggt tttgtacgtt caaatttttc tttagacacg
      301 gctatattcc ttactatagt gctctcccct tcaggagaga gcacgggact ttggtattaa
      361 cccttaggct tatttaccac gggcttcaat tacggcctga gcaacgttac tcggcgcttc
      421 atcatacttc aggaattcca tagtgtatga tgcgcgacct ttggtcagag aacgcagctg
      481 agttgcatat ccgaacattt cagacagcgg tacttcagcg tggatcttaa cgccagtaac
      541 ttcagattcc tgacctttga gcataccacg acgacggctc aagtcaccga taacgtcacc
      601 ggtgttctct tcaggagttt ctacttcaac cttcatgatc ggctcaagca gaactggttt
      661 cgctttctta aagccttctt taaaggcgat agaagcagcc agtttaaacg ccagttcaga
      721 ggagtcaacg tcatggtaag aaccgaagtg cagacgaata cccatgtcta ctaccgggta
      781 gcctgccagc ggacctgctt tcagctgttc ctggatacct ttatcaacgg ccgggatgta
      841 ttcgccaggg attacaccac ctttaatgtc gttgatgaac tcgtagcctt tcgggtttga
      901 acccggctcc agcgggtaca tgtcgataac aacatgacca tactgaccac gaccaccaga
      961 ctgtttcgcg tgtttacctt caacatcggt aactttctgg cggatagttt cacggtaagc
     1021 aacctgcggt ttacctacgt tcgcttcaac gttgaattca cgcttcatac ggtcaacgat
     1081 gatgtcgagg tgcagttcgc ccatacccgc gatgatggtc tggttagatt cttcgtcagt
     1141 ccatacacgg aaagacgggt cttctttagc cagacggccc agagccagac ccattttttc
     1201 ctggtcagct ttggttttcg gttcaactgc gatggagatt accggctcag ggaattccat
     1261 acgttccaga atgatcggcg catccgggtc acacagggtg tcaccagtgg ttacgtcttt
     1321 cagaccgatt gcagctgcga tgtcgcccgc gcgaacttct ttgatctctt cacgtttgtt
     1381 agcgtgcatc tgaacgatac gaccgaaacg ctcacgtgca gctttcacgg agttcagtac
     1441 ggtatcacca gagttaacca caccggagta cacacggaag aaggtcaggt taccaacaaa
     1501 cgggtcggta gcgattttga acgccagtgc agagaacggc tcgtcatcac ttgcgtgacg
     1561 ctcagccgga gtgtctttac cgtcgtccag gataccgttg atcgcaggta cgtcaaccgg
     1621 ggatggcagg taatcaatta ccgcatccag catcgcctga acacctttgt tcttgaacgc
     1681 agaaccacag gttaccagga tgatttcgtt gttcagaacg cgctgacgca gagcaccttt
     1741 gatttctgct tcagtcagtt cttcaccacc cagatatttt tccatcagct cttcagaagc
     1801 ttcagctgcg gattcgatca ggttctggtg ccattcgtta gccagttcaa ccatgtctgc
     1861 cgggatatct tcgtattcga aggttacgcc ctggtcagcg tcgttccagt tgatagcttt
     1921 cattttcacc aggtcaacaa caccggtgaa atgttcttca gcaccaatcg ccagctgcag
     1981 cggaaccggg ttcgcgccca gacgggtttt gatctggtta acaactttca ggaagttcgc
     2041 acccatgcgg tccattttgt taacgaacgc aatacgcgga actttatatt tgtttgcctg
     2101 acgccatacg gtttcagact gcggctgaac accaccaact gcgcagtaaa ccattaccgc
     2161 accatcgaga acacgcatgg aacgttctac ttcgattgtg aagtcaacgt gccccggggt
     2221 gtcgatgatg ttgatgcgat gcggctcata ctgcttagcc ataccagacc agaatgcagt
     2281 agtcgcagcg gaagtgatgg taataccacg ttcctgctcc tgctccatcc agtccatggt
     2341 tgcagcgccg tcatgaactt caccgatttt atggtttaca ccggtgtaga acagaatacg
     2401 ttcggtagta gtggttttac cggcgtcgat gtgcgcactg ataccgatgt tacggtagcg
     2461 tgcgatgggt gttgtacgag ccatttgttt cctcgtttat cttttaggcg ttcaatttaa
     2521 gtagcccaaa gcgggctgct tactggaagc gcccgcctgg tgactaaaac tccgaaggga
     2581 ttaccaacgg tagtgtgcga acgccttgtt ggcttcggcc atacggtgaa cgtcttcacg
     2641 tttcttaact gcagtacctt tgttttctgc agcatcagaa agttcgttcg ccaggcgcag
     2701 agccatggat ttatcaccgc gtttacgagc agcttcaacg atccaacgca ttgccagagc
     2761 attacgacga accggacgga cttcaactgg tacctgataa gtagaaccac caacgcggcg
     2821 agacttaact tctacagtcg ggcgcacgtt ttcgagagct acttcgaatg cttccagttc
     2881 agatttacca gagcgctgag ccagggtctc cagcgcgctg tatacgatag attcagcagt
     2941 agatttttta ccatctacca tcaggatatt tacaaattta gccagcagtt ctgatccgaa
     3001 cttcggatcc ggcagaattt tacgctgacc aatgacgcga cgacgtggca tggaaatact
     3061 ccgttgttaa ttcaggattg tccaaaactc tacgagttta gtttgacatt taagttaaaa
     3121 cgtttggcct tacttaacgg agaaccatta agccttagga cgcttcacgc catacttgga
     3181 acgagcctgc ttacggtctt taacaccgga gcagtcaagc gcaccacgta cggtgtggta
     3241 acgaacaccc gggaggtctt taacacgacc gccacggatc aggatcacgg agtgctcctg
     3301 caagttgtga ccttcaccac cgatgtagga agtcacttcg aaaccgttag tcagacgaac
     3361 acggcatact ttacgcagcg cggagttcgg ttttttagga gtggtagtat atacacgagt
     3421 acatacgcca cgtttttgcg ggcatgcttc cagcgcaggc acgttgcttt tcgcaacttt
     3481 gcgagcacgt ggtttgcgta ccagctggtt aactgttgcc attaaatagc tcctggtttt
     3541 agcttttgct tcgtaaacac gtaataaaac gtcctcacac aatatgagga cgccgaattt
     3601 tagggcgatg ccgaaaaggt gtcaagaaat atacaacgat cccgccatca ccaggccatc
     3661 tggctggagt gcttaaccgt aagtctgacg aaatcagtat agtcaatggg aatgatgtcg
     3721 ttcgaaattc gaccagtcaa accgcgggca ataaggtctt cgttcagagc atagacctta
     3781 atgggggcat tacgcagact ttcaaggtag cggttgccgt caactgcggc agttacgcca
     3841 tcttgcaata atagcagttc gtcaccttca ctgagcagac gcagcagcgc agcaaagtcc
     3901 gtcagccagg gtgaacgatg taatgtgtgc agcataacgc ctcaaaacct caaaataaca
     3961 tcgtagttgg cgagttcgcg gcgtaaggca tctgcttcga gcggcgtggc ttcgaccaca
     4021 aagggtgtct gcggatctaa cccacgttcg cgcagtgaag ccgcgcaaat ccagcactgt
     4081 tcaatatcgt acagacccaa caatttaaaa gtggcaatgt aatcacgcgc cagcactgca
     4141 tcgggctttt gtcctggcag cagctgaaaa acgccatcag caataaagaa gacggccaga
     4201 tcgtcagtta atgcggaagt tgccagtaaa gcatctaaac cttcccggcc tgcagttgta
     4261 ccatgaggcg cagtagaaaa aacaaacgca attcgtttca tcagaactgt accaccctgt
     4321 cacaggtcag cgaggcttcc gccagcgcgc caagtccgct taaggtaaat cccggctgaa
     4381 ggtttgacga agcaagcccc agtcttccgg cctccgtttc atcaacaacg ccacggcgta
     4441 atgctgccgc tacgcagata ttcagcgcca caccatgttg cgcattcaac tgttgccagc
     4501 cgcgcacaag gtcaaattcg tcgcttgccg gtgaggtcaa ttggttagcg ttatagaccc
     4561 cttcccgata gaaaaaaacg ctgcttaact catggccttc tgctatcagc gcctgcgcaa
     4621 actgaaaagc actactcgcc tgttgcgtac cgtatgctgg cccggtcacc acgatggcaa
     4681 aacgcattac ttatcttgcc cctggaaatc accgctcttg aactggcgga tgtagagata
     4741 gacagtgtgt ttggagatgt tcaggcggtc agcaacctgg ttgatcgcgt ctttaatatc
     4801 gaagatccct ttctcgtaga gatttagcac gatctgacga tttttggcgt tattagaaac
     4861 attgcgatcg gcattcactt cttcgatggt gaactccagc gtttgggtaa ccagatcttc
     4921 aacagaagag gcaaagttga cgcttgaacc gacatccgga gtttccggcg gcacaaaagt
     4981 gctcataatc tgcgagaagg gaacatcaag attcatattg atgcacagca gaccaattac
     5041 acgctgttcg cggttacgaa tcgcgatagt cagggacttc attaatacgc cgcttttggc
     5101 gcgagtaaag tagcatttag aaacgctgct atccgctccc gtcatatcgt gcagcatacg
     5161 tagcgccagg tcagtaattg gcgaaccaat cttccggcct gtatgttcac cgttagcaat
     5221 gcgaatggct gaacatttta gatcctgcaa agagtgcaaa acgatttcac agtgggagcc
     5281 aataagcatc gctaacccgt ccaccaccgc ttcgtaggat ttcagaatat caaaatcggt
     5341 ctggtcaaaa ggacgttgat ccagtaaatc caactcactg gtttcgttgg ttaaaagcga
     5401 cctggacatg aaaaaaaaca ctccttttca ggagcctgtc gttaactttt cagggcaggc
     5461 tcattaatga tgcgggtaac taaattaata cagcggaggt tccgctttcc agcactaatt
     5521 atatccggcc tgtaataaaa aaaccgccgc ctggtcaggc ggcggttctt aatgcttatt
     5581 ttttagcaga gtctgcggct ttcgcatcag cttccggctt tgcatcagcc ttcggcgctg
     5641 gtttcacatc cagcagctct acgtcaaaca ccagggtaga attcggtggg atccccggaa
     5701 cacccgcttt gccgtaagcc agttctggtg gaataaccag tttgatctta ccgcctttct
     5761 tgatgttctt cagaccttct gtccaacccg gaataacacc gtccagacgg aaagagagcg
     5821 gttcaccacg ggtgtaagag ttgtcgaact ctttaccgtc gatcagcgta cctttgtagt
     5881 tcactacaac agtatcgctg tctttcggtg cttcgccttt accggcttct actacctgat
     5941 aaaccagacc agtggaagag gttttcacac ctttctcttt ggcaaatttc tcgcggtact
     6001 ctttaccttt tgcttcgtta tcagccgcgt ctttttccat cttcgcctga gcagaagact
     6061 tcacgcgagc ttcgaatgct tgcagagtct gttcgatctc ttggtcggaa agtttgctct
     6121 tatcagcaaa tgcatcctga acaccagcga tcagctgatc tttatccagt ttgatgccca
     6181 gtttttcttg ttctttaaga gagttttcca tgtaacgacc cagcgaagca cccagtgcat
     6241 aagctgattt ctgatcgtca tttttgaacg ctgctttgct gtcagcagtt gtagcaggtt
     6301 ttgcagcttc agcagcaaaa gtgattggtg catgcagggc aacggccatt gtggtcgcca
     6361 gcagcgttac tttaaacagt gatttcatcc atatctccag gatcggggca tctcacccca
     6421 gggttaacta ttatcagaag ggtactataa agcgttgtcg aacaaatcta catacagaca
     6481 cgccctatta tcatctattt tcagactctt tttgtttaaa ttagtttcga tgaccgcgaa
     6541 atgagtgctg tctcgggcag caaagttaag tagaatccgc ggcgaccatt cgacaaaaga
     6601 ggtgaatcat gcaggattta tcattggaag cacgcctggc agagctggag agccgactgg
     6661 cttttcagga aatcaccatt gaagaactga acgtcacggt gaccgctcat gaaatggaga
     6721 tggcgaaact gcgcgatcat ctgcgtctgc tgaccgagaa gttaaaagcc agccagccgt
     6781 cgaacatcgc gtcgcaggct gaagaaacgc ctccgccaca ttattgaggc gtaaaaaaag
     6841 cgggaattcc ccgctttttt gtcacctttt cggtattagt ggcaaccgca accgccgttg
     6901 cctttaccgc cacagcagcc ttcgccaccg tgttcatgac cgtgatcgtg gccatgacca
     6961 ccgcagcaac cgtcgtggtc gtgatcgtgg tggtgatcgt gcgcgccgtg aacgtgacca
     7021 tgagccagtt cttcttcggt cgcttcgcga atcgccacaa cttcaacgtt gaatttcagg
     7081 ttctgaccag ccagcatgtg gttaccatca accactacgt gatcgtcttc aaccgcagtg
     7141 atttcaaccg gtaccggacc ctggtcggtt tcagccagga aacgcatacc tacctgcagt
     7201 tcatcaacgc ccataaatac gtctttagga acgcgctgca ccaggttttc gtcgtactga
     7261 ccgtaagcgt cattcgcgcc aacagcgaca tcaaatttgt cgccaacttc atgaccttcc
     7321 agcgccgttt ccaggccaga gatcagggaa ccgtgaccat gcaggtagtc cagcggcgca
     7381 ctcaccggag actcatcaac caacacaccg tcttctgtac gtacctgata ggccaggctg
     7441 accaccaggt cttttgctac tttcatgata tctcctgagc atgggaagaa tagtggcgca
     7501 gattgtagcg gaattctgca gccgtgtact cactagctta aaaaaactcg gcgcatatcg
     7561 ctagtccgga tgaaaaatcc cgatcacttg ctcatctttg cgaacgtgat cgcgggcttc
     7621 tttgtctgct tctcgcatct gatgtccaca cttaacacat tcaacgatat caatattatt
     7681 ttcgcgccac atcgccattg aatcctgagc ctgacaggcc gggcattttg cgcccgcaat
     7741 aaaacgtttt cggattgcca tctttaccct ctactcaaat tcatcccagc cgtccagctg
     7801 gcgtcgttct tgttgcattt cacgctggaa aatctcttcc agttcgcgtc gggcttccct
     7861 ggcgcgagaa atttgtacgg tatcagcatg catcgggatt aactcccgca gcattcgcat
     7921 atccaggcgg cgaaaatgca gttgcgcgcg ctgcgcctga tgcggatgca tgccaagcgt
     7981 gaccagcgtc ttgcgcccca gctctaacgc actggagaat gtttcacggg aaaactgcgt
     8041 cacccctgcc tgtaataact catgcgcttc cacacgtccg cgcgctcgcg caagaatatg
     8101 caaatgcgga aagtgctgct ggcatatttc caccagcttc atagtgtctt ccggctcgtt
     8161 acaggtaatg acgatagact cagcggcctc tgcacccgca gaacgtaaaa gatctacctg
     8221 cgtggcgtcg ccgtaataaa ctttgtagcc atatttgcgc atcaggttaa cggcactgat
     8281 atcccgctcc agtacagtaa tgcgcatttt atttgccatc agcaaacgac caatcacctg
     8341 accaaaacgc ccaaagccca cgacaataac ctgcggttta tcatcgttga cccatggttt
     8401 ttcgtcttct tcttccggtc cgttaaactg gcgggatagc catttatcta ccagcttcat
     8461 cagcagcggc gtggtcatca tggaaagcgt caccgtcacc agcaacagcg ccatctggtc
     8521 gccctggaat aagcgttgtg aagaagcgga agaaaagagg acaaaggcaa actcaccgcc
     8581 ctgactcaac acgccagcaa actgcatccg ctctgagcta cgcacgccat acaatcgcgc
     8641 cagcagatac agcacgagaa ttttcaccgc caccagcaca accacactta tcactaccca
     8701 caacagatgg gtataaagca ccccgaggtt gagtgacatg ccgacagaga taaagaacaa
     8761 accgagcagc aagcctttga agggatcgat agccgtttcc agttcatggc gatattcact
     8821 ttccgccagt agcacacccg caataaacgt accgagcgcc atcgacaacc ccagcgcatc
     8881 cataaacaat gcggaaccca acaccagcag cagcgtcgcg gcggtgaaca cttcccgcac
     8941 accagaagct gcaataaaac ggaataccgg acgcagtaaa tagcgcccgc caatcagcat
     9001 gccgacaaac gccagcacct tcatgccgat cttcatccag tcgaaatgtt cgtctgccga
     9061 acccgccaac aacggcacta acgccagtgc cgggatcacc gccagatcct gaaacagcag
     9121 taccgagaaa cctaactggc cggattcgct gcgattcatc cctttttcac gcatcaactg
     9181 caatgccatt gcggttgaag acatcgcaag gccaatgcca ccgaccaccg ccgcctgcca
     9241 ggcgaaatcc gtcagcatca ataatcccgc cagcaacgcc gcgcttaaca gcacctgtgc
     9301 cgcgcctacg ccaaaaatcg aacgccgcag ttgccaaagc ttggagggat tcaactcaag
     9361 gccgatgata aacatcagga ataccacgcc gagttccgaa aagtggagga tctcatcgac
     9421 gtcgctaata aaccccagcc cccacgggcc aatcgcaatc cccgccagca aatatcccaa
     9481 cactgcacca atacccagcc gcgatgccag cggcaccgca gccaccgccg cgaagagaaa
     9541 cagcactcct gcgagtaaaa aatcagaacc ttccatcagc ggcctcctgg agacaacgga
     9601 tttgccagcc agtcaccgta ggctctggcg tggctcgcca gctcctgtgc gctttgccgt
     9661 ctcgcccagt aaataatgat ggggcttaac caatgcatcc ggcacatgcc cgccgccagt
     9721 tcaaaggggc gcagaacatc gctcatcgga tagcgattca acgcgtcata acggtaagca
     9781 ctttccggct ccccggtggt aatcacgcta cgccagtact ttcccgccag ttggtttccc
     9841 cccggtccgc tggcaaaacc acggcttaat acccggtcca gccactcttt cagtagcgcc
     9901 gggcagctat aggtataaag aggatgctga aagacaatca cctcgtgctc gcgcagtaat
     9961 gcctgctcac gagggatatc aataaaaaag tcgggatagt gcgcgtaaag gtcgtgcacg
    10021 gtaacattgc tgagctgcgt ggccggttta agcagaaccc ggtttgccac cgagtcctga
    10081 gattccggat gggcatacag cagcaaaact ttcgctggct gagacatcat ccccctcccg
    10141 gtatggtttt tgtgtatagt cgctgttttg ggctaccatt gcgcccggtg cggcagctcg
    10201 cccatacatt acattatcat aatgataagt taacatagtc tgaacatacg gcgccttatg
    10261 attgtttttt cctcgttaca aattcgtcgc ggcgtgcgcg tcctgctgga taatgccacc
    10321 gccaccatca accctgggca gaaagtcggc ctggtgggta aaaacggctg tggtaaatct
    10381 accctgctgg cattgctgaa aaatgaaatc agcgccgacg gcggcagcta cacctttccg
    10441 ggaagctggc aactggcgtg ggtgaatcag gaaacaccgg cgttaccgca agcggcgctg
    10501 gaatatgtca ttgacggcga ccgtgaatat cgtcaactgg aagcgcagct acacgacgcc
    10561 aacgaacgta acgacgggca agccattgca accattcatg gcaagctgga tgctattgac
    10621 gcatggagta ttcgctcccg tgccgccagc ctgctgcacg gcctcggttt cagcaatgaa
    10681 caactggagc gcccggtaag tgatttctcc ggtggctggc gtatgcgtct taaccttgcc
    10741 caggcgctga tttgccgttc agacttgctg ctgctcgacg aaccgactaa ccacctcgat
    10801 ctcgatgccg ttatctggct ggaaaaatgg ctgaagagct atcagggcac gctgatcctg
    10861 atctctcacg accgcgactt cctcgatccg atcgttgata aaattattca tatcgaacaa
    10921 caaagcatgt tcgagtacac cggcaactac agttcgtttg aagtacagcg cgccacccgt
    10981 ctggcgcagc aacaagcgat gtacgaaagc cagcaggaac gcgtagcgca tctgcaaagt
    11041 tatatcgacc gtttccgtgc caaagccacc aaagcgaagc aggcccagag ccgtattaag
    11101 atgctggagc gtatggagct gattgccccg gcgcacgtcg acaacccgtt ccgctttagc
    11161 ttccgcgcgc cggaaagcct gcctaatccg ttattaaaga tggaaaaagt cagcgcaggc
    11221 tatggtgatc gcattattct cgactcgatt aaactgaatc tggtccccgg ctcgcgcatt
    11281 ggtctgctag gccgcaacgg cgcgggtaaa tcgacattaa tcaaactgtt agccggtgaa
    11341 cttgcgccag tcagcggtga aattggtctg gcgaaaggga tcaagctcgg ctacttcgcc
    11401 cagcatcaac ttgaatacct gcgcgccgac gaatcgccta ttcaacatct ggcacgttta
    11461 gcgccgcagg agctggaaca aaaactgcgt gattacctcg gcggctttgg tttccagggc
    11521 gataaagtaa ccgaagaaac gcgccgcttt tccggtgggg aaaaagcccg cctggtgctg
    11581 gcattaattg tctggcagcg tccgaatctg ctgctgctcg acgaaccgac taaccacctt
    11641 gacctcgaca tgcgtcaggc actcactgaa gcattaatcg agttcgaagg cgcgctggtt
    11701 gtcgtctcgc acgaccgtca tttgctgcgt tccaccactg acgatctcta cctggttcac
    11761 gatcgtaaag tcgaaccgtt cgacggcgat ctggaagatt atcaacagtg gttgagcgac
    11821 gtacaaaagc aggaaaacca ggccgacgaa gcgccaaaag agaacgcgaa cagcgcccag
    11881 gcacgtaaag atcagaagcg tcgggaagcg gagctgcgtg cgcaaaccca gccactgcgt
    11941 aaagagattg cccgtctgga aaaagagatg gagaagctga acgcgcaact ggcgcaggcg
    12001 gaagagaaac tcggcgacag cgaactgtat gaccagagcc gtaaagcgga gttgaccgcc
    12061 tgcctgcaac agcaagccag cgccaaatcc ggcctggaag agtgcgaaat ggcgtggctg
    12121 gaagcccagg agcagcttga gcagatgctg ctggaaggcc aaagcaactg atggcgcaga
    12181 taacgacgac cgatgccaat gaatttagca gcagtgctga attcacccct atgcgcggct
    12241 ttagcaattg tcatctgcaa accatgctgc cgcgtctgtt tcgtcgcaag gtgaaattca
    12301 ccccgcactg gcatcgactg gagttgcccg acggcgattt tgtcgatctc gcatggagtg
    12361 aagatcctgc acaggcgcgg cataaaccgc gtttagtggt atttcacggg ctggaaggca
    12421 gtctcaatag cccttacgct cacggtctgg ttgaggcggc gcaaaagcgc ggctggctgg
    12481 gcgtggtgat gcattttcgc ggatgcagcg gtgaaccaaa ccgtatgcac cgcatttacc
    12541 attcgggcga aaccgaagac gccagttggt ttttacgctg gctgcaacgc gagtttggtc
    12601 atgcgccaac ggctgccgtc ggctattcgc tcggcggtaa tatgctggcc tgtttgctgg
    12661 caaaagaagg taatgatctc ccgattgatg cggcggtgat tgtctctgcg ccgtttatgc
    12721 tggaggcctg tagttaccat atggaaaagg gcttttcccg catttatcag cgttacttgc
    12781 tgaacctgtt aaaagccaat gccgcgcgca agctggcagc ctaccccgga acactgccga
    12841 ttaatctcgc gcagttaaaa tcggtacgtc gcatccgtga atttgacgat ctcatcaccg
    12901 ccagaattca cggctacgct gacgctatcg actattatcg tcagtgtagc gccatgccga
    12961 tgctcaatcg gatagccaaa ccgacactga ttattcacgc caaagacgat ccgtttatgg
    13021 atcatcaggt gatcccgaaa ccggaaagtc tccccccgca ggtggagtat cagctgactg
    13081 aacatggcgg tcatgttggc tttattggcg gtacattact tcatccgcaa atgtggctgg
    13141 agtcacgcat tcctgactgg ttaacaacgt atctggaggc gaaatcatgt tgattccgtg
    13201 gcaagacctc tcccccgaaa cgctggaaaa tttaattgaa agctttgtgt tacgtgaagg
    13261 caccgattat ggtgaacatg agcgtacact tgaacagaaa gtcgccgacg tcaaacgcca
    13321 gctacagtgc ggagaagcgg tgctggtatg gtcggagctg cacgaaacgg tcaatatcat
    13381 gccgcgcagt cagtttcgcg aataacctgc aaccgtcggc ggacgagata ataatgatag
    13441 ctaagtcatg gagttactat gtctgccaaa catccggtca ttgcggtaac aggatccagc
    13501 ggcgcgggga ccaccaccac cagcctcgcg tttcgtaaaa tattcgcgca gttaaatctg
    13561 catgcagccg aggtggaagg cgacagtttt caccgttata cccgcccgga aatggacatg
    13621 gcgatccgca aagcgcgcga cgccgggcgg catatcagct acttcggccc cgaagcgaac
    13681 gacttcggcc ttctggaaca aaccttcatt gaatacggtc agagtggcaa agggaaatct
    13741 cgcaaatatc tgcataccta cgatgaagcc gtaccgtgga atcaggtacc ggggacattc
    13801 accccctggc aatctttacc ggaacccact gatgtactgt tttatgaagg tttacacggc
    13861 ggcgtagtca cgccacagca taacgttgcg cagcatgtgg acttactggt cggcgtggtg
    13921 cctatcgtta accttgagtg gattcaaaaa ctgatccgcg acaccagcga gcgcgggcac
    13981 tcacgagaag cagtgatgga ctcggtagtg cgttcaatgg aagactatat caactacatc
    14041 acaccgcagt tttcccgcac ccatcttaac ttccagcgcg ttcccaccgt cgacacctca
    14101 aacccgttcg cggcaaaagg tatcccgtca ctggatgaaa gctttgtggt gatccatttt
    14161 cgtaatctgg aagggatcga tttcccctgg ctgctggcga tgttgcaagg ctcattcatt
    14221 tcccacatca atacgttagt ggtgcctggc ggcaaaatgg gtctggcaat ggaattaatt
    14281 atgctgccgc tggtgcaacg attgatggaa ggaaagaaaa tcgagtaacg ctgctattac
    14341 gccggataaa atactatccg gcttcacaac gggatagtta aatcacgcgg caaccacttc
    14401 atacgagtga gtaatattca ccgctttttc cagcatcagc gccactgagc aatatttctc
    14461 ggcagaaaga tcaaccgcac gcgcaaccgc tgcgtctttc agatcgcgac cggtgacgat
    14521 aaaatgtaga ttaatgtgcg taaacaggcg tggtgcctct tcgcggcgct cagaggtcaa
    14581 ttttacttca caatcgacca catcctgacg ccctttttgc aggatagaaa ccacatcgat
    14641 ggcactgcaa ccacccgccg ccatcaacac catttccatc gggcttggtg ctttatcgcc
    14701 tgagttgccg tccattaaaa tctggtgacc agaggcggat tcgcccagaa aagttaaccc
    14761 ttcgacccac ttcactcgcg cttgcatttt tgctactcca ctgcgtcaat tttcctgaca
    14821 gagtacgcgt actaaccaaa tcgcgcaacg gaaggcgacc tgggtcatgc tgaagcgaga
    14881 caccaggaga cacaaagcga aagctatgct aaaacagtca ggatgctaca gtaatatatt
    14941 gatgtactgc atgtatgcaa aggacgccac attaccgtgc agtacagttg atagcccctt
    15001 cccaggtagc gggaagcata tttcggcaat ccagagacag cggcgttatc tggctctgga
    15061 gaaagcttat aacagaggat aaccgcgcat ggtgcttggc aaaccgcaaa cagacccgac
    15121 tctcgaatgg ttcttgtctc attgccacat tcataagtac ccatccaaga gcacgcttat
    15181 tcaccagggt gaaaaagcgg aaacgctgta ctacatcgtt aaaggctctg tggcagtgct
    15241 gatcaaagac gaagagggta aagaaatgat cctctcctat ctgaatcagg gtgattttat
    15301 tggcgaactg ggcctgtttg aagagggcca ggaacgtagc gcatgggtac gtgcgaaaac
    15361 cgcctgtgaa gtggctgaaa tttcgtacaa aaaatttcgc caattgattc aggtaaaccc
    15421 ggacattctg atgcgtctgt ctgcacagat ggcgcgtcgt ctgcaagtca cttcagagaa
    15481 agtgggcaac ctggcgttcc tcgacgtgac gggccgcatt gcacagactc tgctgaatct
    15541 ggcaaaacaa ccggatgcta tgactcaccc ggacggtatg caaatcaaaa ttacccgtca
    15601 ggaaatcggt cagattgtcg gctgttctcg tgaaaccgtg ggacgcattc tgaagatgct
    15661 ggaagatcag aacctgatct ccgcacacgg taaaaccatc gtcgtttacg gcactcgtta
    15721 atcccgtcag agtggcgcgt tacctggtag cgcgccattt tgtttccccc gatgtggcgc
    15781 agactgattt atcaccccga tatcaactat gcacttcgac aaacgctggt gctatgtttg
    15841 cccgtggccg ttgggttaat gcttggcgaa ttacgattcg gcctgctctt ctccctcgtt
    15901 cctgcctgtt gcaatattgc gggccttgat acgcctcata aacgtttttt caaacgctta
    15961 atcattggtg cgtcgctgtt tgccacctgt agcttgctga cacaggtgct actggcaaaa
    16021 gatgttcccc tgcccttttt gctgaccgga ttaacgctgg tacttggcgt cactgctgag
    16081 ctggggccat tgcacgcaaa attgcttccc gcatcgctgc tcgccgccat ttttaccctc
    16141 agtctggcgg gatacatgcc ggtctgggaa ccgttgctca tctatgcgct gggcactttg
    16201 tggtacggat tgtttaactg gttttggttc tggatctggc gcgaacaacc gctacgcgag
    16261 tcactaagtc tgctgtaccg tgaactggca gattactgtg aagccaaata cagcctgctt
    16321 acccagcaca ccgaccctga aaaagcgctg ccgccgctgc tggtgcgcca gcaaaaagcg
    16381 gtcgatctaa ttacccagtg ctatcagcaa atgcatatgc tttccgcgca aaataatacc
    16441 gattacaagc ggatgctgcg tattttccag gaggcgctgg atttgcagga acatatttcg
    16501 gtcagtttgc atcagccgga agaggtgcaa aagctggtcg agcgtagcca tgcggaagaa
    16561 gttatccgct ggaatgcgca aaccgtcgcc gctcgcctgc gcgtgctggc tgatgacatt
    16621 ctttaccatc gcctgccaac gcgttttacg atggaaaagc aaattggcgc actggaaaaa
    16681 atcgcccgcc aacacccgga taatccggtt gggcaattct gctactggca tttcagccgc
    16741 attgctcgtg tgctgcgcac ccaaaaaccg ctctatgccc gtgacttact ggccgataaa
    16801 cagcggcgaa tgccattact tccggcgctg aaaagttatc tgtcactaaa gtctccagcg
    16861 ctacgcaatg ccggacgact cagtgtgatg ttaagcgttg ccagcctgat gggcaccgcg
    16921 ctgcatctgc cgaagtcgta ctggatcctg atgacagtat tgctggtgac gcaaaatggc
    16981 tatggcgcaa cccgtctgag gattgtaaat cgctccgtag gaaccgtggt cgggttaatc
    17041 attgcaggcg tggcgctaca ctttaaaatt cccgaaggtt acaccctgac cttgatgctg
    17101 attaccaccc tcgccagcta cctgatattg cgcaaaaact acggctgggc gacggtcggt
    17161 tttactatta ccgcagtgta taccctgcaa ctgttgtggc tgaacggtga gcagtacatc
    17221 cttccgcgtc ttatcgatac cattattggt tgtttaattg ctttcggcgg tactgtctgg
    17281 ctgtggccgc agtggcagag cgggttattg cgtaagaacg cccatgacgc tttagaagcc
    17341 tatcaggacg cgattcgctt gattctgagc gaggacccgc aacctactcc actggcctgg
    17401 cagcgaatgc gggtaaatca ggcgcataat actctgtata actcattgaa tcaggcgatg
    17461 caggaaccgg cgtttaacag ccattatctg gcagatatga aactgtgggt aacgcacagc
    17521 cagtttattg ttgagcatat taatgccatg accacgctgg cgcgggaaca ccgggcattg
    17581 ccaccggaac tggcacaaga gtatttacag tcttgtgaaa tcgccattca gcgttgtcag
    17641 cagcgactgg agtatgacga accgggtagt tctggcgatg ccaatatcat ggatgcgccg
    17701 gagatgcagc cgcacgaagg cgcggcaggt acgctggagc agcatttaca acgggttatt
    17761 ggccatctga acaccatgca caccatttcg tcgatggcat ggcggcagcg accgcatcac
    17821 gggatttggc tgagtcgcaa gttgcgggat tcgaaggcgt aatacaggct aaaccatcgg
    17881 atgaggtgtt cacgccgcat ccgacatctt ttgcctgatg cgtcttattt acgccccaac
    17941 caccttcgcc accgcgtggg cgaaacgatg catcccttca tcgatatccg catcttccac
    18001 caccagcgac ggcgcaaaac gcatcacatc aggcccggca ttcagcacca ttacgccttc
    18061 ctctgcaccc gcatacagga aatcacgcgc ccgacctttg tactgtggtt tcagctctgc
    18121 gccaatcaac agccccatac cgcgaatatc gctaaacaca tcgtactgct gatcgatctt
    18181 ctgcaaatgg tcaacaaaac gctggcgttt cgcctgaata ccttccagca cttcaggggt
    18241 attgatgata tcaaacgccg cgcccgctac tgcacaggcc agaggattac cgccgtaggt
    18301 ggaaccgtga gaaccaggat gaaacgcgga agcaatttcc gccgtggtca gcatggcgct
    18361 aatcgggaag ccgccgccta acgctttcgc agaggtcaga atatccggcg tcacgccgta
    18421 gtgcatgtaa gcaaacaaat cgccggtccg ccccatcccg cactgtactt catcaaacac
    18481 caataatgcc tgatgttgat cgcacagctc gcgcaagccc tgcaaaaact ctggcgtcgc
    18541 tgccgtcaca ccgccctcac cctggatcgg ctcaaccacc accgcacagg tgtgatcatc
    18601 catcaccgct ttcactgcgt ggagatcgtt aaagggaacg tggatgatgt ctgccggttt
    18661 tggcccaaag ccatcggaat attttggttg cccgcccacc gagacggtaa acagcgagcg
    18721 accatgaaaa gcgttatgga aggcgataat tttggttttg aacgggctat gacgcacaca
    18781 ggcgtaatgg cgtgccagtt taaaggcggt ttcgttagct tccgtgccgg agttcataaa
    18841 caccacgcgt tcggcaaacg ttgcctcaat cagtttacga ccaagacgca gcgccggttc
    18901 attggtgaaa acgttactga tatgccacag agtttcgccc tgggttttta acgcgttcac
    18961 cagcgcagga tggcaatggc ccaacgccgt aactgcaatg ccacccgcga aatcgacata
    19021 ctccttgcct tgctgatccc agattcggct gccctgacct tttaccggaa taaactctgc
    19081 cggagcataa atcggcagga tcacttcatc gaaagtcgcg cgtgtaattg ctgtttgttc
    19141 aattgccatc tcatgatcac cctgttacgc ataaaccaat gtgaaattat aatcacaaaa
    19201 tatgcataaa aaatcactta atagcaatca gaaatcagcg atgcaggaaa ttagccagca
    19261 gttgatgtcc ttgttcgcta agaatacttt ctggatggaa ttgcacacct tccagatccc
    19321 actggcgatg gcgaatcccc ataatctcgc gggtttcgct ccaggccgtc acttcaaagc
    19381 actccggtaa tgagtcaggt tccaccacca gcgaatggta gcgtgtcacg gtgagtggat
    19441 ttgccagccc cttaaatacg cccacaccat tatgtgtaat cggcgaggtt ttgccgtgca
    19501 tgacctttgc ggcgcgcaca actttgccgc caaatgcctg tgccattgcc tggtgaccga
    19561 ggcagacgcc aagaatcggc aaacgcccgg catagtgacg aataacgtca agggagatcc
    19621 cggcttcatc tggcgtacag gggccgggtg agatgacaat tttttgtggt ttaagggcgt
    19681 cgatatccgc caacgtcaac gcatcgttgc gcttaaccaa cacatccgcc cccagttcac
    19741 aaaagtactg gtagaggttc caggtaaaag aatcgtagtt atcaataagc aggatcatgg
    19801 cggctccggt acgaaagaac cgcgctattt tactcagatt ccccgacttc gcttaccact
    19861 ttgctaaata tcatctgcag cgcggtgaga tcccccattg ccccattctg atttgcctga
    19921 ttccaggcct ctttttcgat accctgccag ctcagttgat atccggcatg aatcgccagt
    19981 tgctcgaaga agatccgctg tgccaaacca cttcccaccc ggaagggatg cagcacgttg
    20041 atttcacaat agtaatgcgc caaccgctcg acgaatttat ctttctcaag gctagtcaga
    20101 tacttctctt cctccaaatc ctgcatcagg gcattgccct ctttttcgag ataggcaaag
    20161 tggcagaacg gcgtatctcc ctgataaata tcaacttcac gcagttgccc tgcccagtcg
    20221 aaaatatcct gatacagctg gcgatggata gtgcgcaaat gcggtaaacc gcgcaccagc
    20281 ggaccaagct caatggtcgc agcacgcagc gccgtcattt cgtaagcggc ctgttccagc
    20341 cgctgctgct ggcggatgtt gagcttgtta cgcatgatat cgagacccgg gtagagatat
    20401 ggatcgcgcc cttcgccgaa tttatcgctc atagtgcctc ctcagcgctt caaggcgcgc
    20461 taaagcctct gcggcagtaa gagtgactaa aggcatctcg acgccttcaa gacggcgact
    20521 ggcctggaaa ttacgattac gctgaagctc ccagagacgg gacttttgct tatcggtgag
    20581 tttcttcact tgatgcctcc ctgaacgtgt ccatttgcca caagtataag cggcaaatcc
    20641 gggttacgcc gggagagcag aagcgcgggc aagattgccc gcgcgagaaa tcattacggc
    20701 aggactttag cggaaaggat aactaccggt tttgacggca cattctggta cggaccaacg
    20761 tcatgagtcg gcacctggga aatcttatcg gcaacgtcca tgcctttcac cactttacca
    20821 aataccgcgt aaccgaaatc acgctgaccg tggtcaagga aggcgttatc ggcaacgttg
    20881 ataaagaact ggctggtggc gctgtctttg tcagcggtac gcgccatcgc gatggtgcca
    20941 cgcgtgttgc gcaggccgtt atcagcttca tttttgattg gcgggtttgg ttttttctgc
    21001 tgcatctgct cggtgaaacc gccgccctga atcataaagc caggaatgac gcggtgaaag
    21061 gtcgtgttgt tataaaaacc actgttcaca taatcgacaa agttttgcac agacactggc
    21121 gctttttgtt tatccagctc cagttcgatg ttaccagctg aggttgtcaa caatacgtgc
    21181 gggtcccctt tcgctgccat tgctgcggga gaaagagcag aaagagcgaa aacagcagcc
    21241 atcgccgcca gggtcgattt gaacatgaga tttccttaac aaacagagca gaaaaaaagc
    21301 aagtgaagag attctaaata gccttcaaga acaaggccat ccctttacct aattttacgt
    21361 atctgaaata tatgtaacct gaggataact ttttattccg tgatcaaaat cacctcttaa
    21421 aatgcaattt agcaaccgat tgcaataaaa catttaatca gatcacaaaa tcgcctaaaa
    21481 tcgcccgctc gcggcatagc ccgctatgcc attttatttt tgaacgcagg ccaatcatga
    21541 ctaacagcaa tcgcatcaag ctcacatgga ttagctttct ttcctacgca ctgaccggtg
    21601 cgttggttat tgtcaccggg atggtgatgg gaaatatcgc cgattatttc aatctgcctg
    21661 tttccagcat gagtaacacc ttcaccttcc tcaatgccgg cattttaatc tctatcttcc
    21721 tcaacgcctg gctgatggaa atcgtcccgt tgaaaacgca gttacgtttt ggctttctcc
    21781 tgatggtgct ggcggttgcc ggtttgatgt tcagccacag cctggcgctg ttctcggcgg
    21841 cgatgttcat tctcggggtg gtcagcggca tcaccatgtc gattggtaca ttcctggtaa
    21901 cacaaatgta tgaaggacgt cagcgcggtt cacgcctgtt atttaccgac tccttcttca
    21961 gtatggccgg gatgattttc ccaatgatcg ccgcatttct gctggcgcgt agcattgagt
    22021 ggtactgggt ttatgcctgc atcgggctgg tgtatgtcgc tatttttatt ctgaccttcg
    22081 gctgtgagtt cccggcgctg ggcaaacatg cgcccaaaac ggatgctccg gtagagaaag
    22141 aaaagtgggg gatcggcgta ctgtttctct ctgttgcggc gctgtgctac atcctcggtc
    22201 agttaggttt tatctcctgg gtgccggaat atgccaaagg cctgggcatg agcctgaacg
    22261 acgcaggcac gctggtaagt aacttctgga tgtcgtacat ggtcggcatg tgggcattca
    22321 gctttattct tcgcttcttt gatttgcaac gtatcctgac cgtactggct ggtctggctg
    22381 cgattctgat gtacgtcttt aacaccggaa caccggcaca tatggcgtgg tcaattctcg
    22441 ccctgggctt cttctccagc gcgatctata ccaccatcat caccctgggt tcacagcaga
    22501 ccaaagtacc gtcgccaaaa ctggttaact ttgtcctgac ctgcgggacc atcggtacta
    22561 tgttgacctt tgtggttacc ggcccgattg ttgaacatag tggtccgcag gcggcgctgc
    22621 tgacggcaaa cggtctgtac gctgtcgtct ttgtgatgtg cttcctgtta ggtttcgtca
    22681 gccgtcaccg tcagcataac accctgacct ctcattaatt gttcatgccg ggcggcacta
    22741 tcgtcgtccg gccttttcct ctcttaccct gctacgtgca tctatttcta taaacccgtt
    22801 caatttgtct gttttttgca caaacatgaa atatcagaca attccgtgac ttaagaaaat
    22861 ttatacaaat cagcaatata ccccttaagg agtatataaa ggtgaatttg atttacatca
    22921 ataagcgggg ttgctgaatc gttaaggtag gcggtaatag aaaagaaatc gaggcaaaaa
    22981 tgagcaaagt cagactcgca attatcggta acggtatggt cggccatcgc tttatcgaag
    23041 atcttcttga taaatctgat gcggccaact ttgatattac cgttttctgt gaagaaccgc
    23101 gcatcgctta tgaccgcgta cacctctcgt cttacttctc tcaccacacc gccgaagagc
    23161 tgtcgctggt gcgcgaaggc ttctacgaga aacacggcat caaagttctg gtcggcgaac
    23221 gcgctatcac catcaaccgt caggagaagg tgattcactc cagcgccgga cgtaccgttt
    23281 tttatgacaa gctgatcatg gcgaccggtt cctacccgtg gatcccgcca atcaaaggtt
    23341 ctgatactca ggactgcttt gtctatcgca ctattgaaga cctcaacgcc attgaatcct
    23401 gcgcccgtcg cagcaaacgc ggtgccgttg ttggtggcgg cctgttaggt ctggaagccg
    23461 ctggcgcgct gaaaaactta ggcattgaaa cccacgttat cgaatttgcc cctatgctga
    23521 tggcggaaca gcttgatcag atgggcggcg agcagctgcg tcgcaaaatc gaaagtatgg
    23581 gcgtgcgcgt tcacaccagc aaaaacactc ttgagattgt gcaggaaggt gttgaagcgc
    23641 gtaaaaccat gcgttttgcc gacggcagcg aactggaagt cgactttatc gtcttctcta
    23701 ccggtatccg tccgcgcgat aagctggcaa cccagtgtgg tctggacgtt gctccgcgtg
    23761 ggggtatcgt cataaatgat tcctgccaga cttccgatcc ggatatctac gccatcggtg
    23821 aatgcgcaag ctggaacaac cgtgtatttg gtctggtagc accaggctac aaaatggcgc
    23881 aggtcgccgt tgaccatatt cttggtagcg aaaacgcctt tgaaggtgca gaccttagcg
    23941 ccaagctgaa actgctgggc gtagacgtag gcggtattgg tgatgcgcac ggtcgcacgc
    24001 ctggcgcacg tagctacgtt tacctcgacg aaagcaaaga gatctacaaa cgcctgattg
    24061 tcagcgaaga caacaaaacc ctgctcggtg cggtactggt gggcgatacc agcgactacg
    24121 gcaacctgct gcaactggtg ctgaacgcta tcgaactgcc ggaaaacccg gattctctga
    24181 ttctgccggc gcactcgggt agcggtaagc cgtctatcgg tgttgataaa ctgccggaca
    24241 gcgcgcaaat ctgctcctgc ttcgacgtca ccaaaggcga cctgattgct gctatcaaca
    24301 aaggctgcca caccgttgcg gcgctgaaag ccgaaaccaa agccggtacg ggctgcggcg
    24361 gttgtattcc gctggtcact caggtactga acgcggaact ggcgaaacag ggtatcgaag
    24421 ttaacaacaa cctgtgtgaa cactttgctt attcgcgtca ggaactgttc catttgatcc
    24481 gcgttgaagg cattaaaacc ttcgaagaac tgctggcgaa acacggcaaa ggttacggtt
    24541 gtgaagtttg taaaccgacc gtcggttcgc tgctggcctc ctgctggaac gaatacattc
    24601 tgaagccgga acatactccg ctgcaggatt ctaacgacaa cttcctcgct aacatccaaa
    24661 aagacggcac ctactcggtg atcccgcgtt ctccgggtgg tgaaatcacc ccggaagggc
    24721 tgatggcagt gggtcgtatc gcgcgtgaat ttaatctcta caccaaaatc accggctccc
    24781 agcgcctggc gatgtttggc gcacagaaag acgatctgcc ggagatctgg cgtcagctga
    24841 ttgaagcagg tttcgaaacc ggtcatgcct atgcgaaagc actgcgtatg gcgaaaacct
    24901 gcgtgggtag cacctggtgc cgctatggcg ttggcgacag cgtcggcctc ggcgtggaac
    24961 tggaaaatcg ctacaaaggc atccgtacgc cgcacaaaat gaagttcggt gtctccggct
    25021 gtacccgtga atgttcagaa gctcagggta aagacgtggg tattatcgcc actgaaaaag
    25081 gctggaacct gtatgtttgc ggtaacggcg gcatgaaacc gcgtcatgcg gatctgctgg
    25141 cagcggatat cgatcgcgaa acgctgatta aatatcttga ccgcttcatg atgttctaca
    25201 tccgtactgc cgacaaactg acgcgtaccg cgccgtggtt agaaaacctc gaaggtggca
    25261 tcgattacct gaaagcggtg atcattgacg acaaactggg gctgaacgca catctggaag
    25321 aagagatggc gcgcctgcgt gaagcggtag tgtgtgagtg gactgaaacg gtcaataccc
    25381 cgtctgcgca gactcgcttc aaacacttca tcaacagcga caagcgtgac ccgaacgtgc
    25441 agatggtgcc agagcgcgaa cagcaccgtc cggcaacgcc gtatgaacgt atcccggtaa
    25501 ctctggtgga ggacaacgca tgagccagtg gaaagacatc tgcaaaatcg atgacatcct
    25561 gcctgaaacc ggcgtctgcg cgctgttagg tgacgaacaa gtagcaattt tccgcccgta
    25621 tcacagcgac caggtgtttg cgatcagcaa catcgatccg ttcttcgagt ccagcgtgct
    25681 gtcacgcggg ctgattgcgg aacaccaggg cgagctgtgg gtcgccagcc cgctgaaaaa
    25741 gcagcgtttt cgcttaagcg acggcttgtg catggaagac gaacagtttt ccgtcaagca
    25801 ttacgacgcg cgagtgaaag acggcgtggt gcagctgcgc ggttaatatt ttaacgggag
    25861 gcgcaatgcc tccccctttt tgcatggtcc tgtaataacc ttcggtatat tgcaggacat
    25921 tttttaaact ttttgtttta ttttttgttt ttatttttta aaggataatc aaatgtttac
    25981 agacactatt actaagtgtg cggctaacgc tgcgcgcatt gcacgcctgt cggcaaataa
    26041 cccgctcggc ttttgggtca gctccgccat ggcgggcgcg tatgtgggtc ttgggatcat
    26101 cctgattttc acgctcggta atttgctcga cccgtccgta cgtcctctgg tgatgggtgc
    26161 gacctttggt atcgccttaa cgctggtgat tatcgccggt tctgaactgt tcaccggaca
    26221 caccatgttc ctcacctttg gagtgaaagc gggcactatc agccacgggc aaatgtgggc
    26281 aatcctgccg caaacctggc tgggtaacct ggtcggttcc gtctttgttg ccatgctcta
    26341 tagctggggt ggcggtagcc tgctgccggt cgataccagc atcgttcact ccgtcgcgct
    26401 ggctaaaacc actgcaccgg caatggtact gttcttcaaa ggtgcattgt gtaactggct
    26461 ggtttgcctg gcaatctgga tggcgctgcg cactgaaggg gcggcgaaat ttatcgctat
    26521 ctggtggtgt ttgctggcat ttatcgcgtc cggctacgag cactccatcg ctaacatgac
    26581 gctgttcgcc ctctcctggt tcggcaacca cagcgaagcc tacacgctgg cgggtattgg
    26641 tcataacctg ctgtgggtga cgctgggtaa tactttatcg ggtgccgtat tcatgggatt
    26701 gggttattgg tatgctacgc cgaaagcgaa tcgtccggtt gcggacaaat ttaatcaaac
    26761 tgaaacggct gccggttaat tattaagggg tttttacgtg gatcatttgc ctatattttg
    26821 ccaattacgc gatcgcgact gtctgattgt cggcggtggt gatgtcgcgg aacgcaaagc
    26881 aaggttgctg ttagacgcag gcgctcgctt aacggtgaat gcattagcgt ttattccaca
    26941 gttcaccgca tgggcagatg caggcatgtt aaccctcgtc gaagggccat ttgatgaaag
    27001 ccttctcgac acctgctggc tggcgattgc agcgacggat gatgacgcgc ttaaccagcg
    27061 cgtcagcgaa gccgctgaag ctcgtcgcat cttctgtaac gtggtcgatg cgccgaaagc
    27121 cgccagcttt attatgccgt cgattattga ccgctcgccg ctcatggtag cggtctcctc
    27181 tggcggcacc tctccggttc tggcgcgcct gttgcgcgaa aaactcgaat cactgctgcc
    27241 gttacatctg ggccaggtag cgaaatacgc cgggcaatta cgcgggcgag tgaaacaaca
    27301 gttcgccacg atgggtgagc gtcgccgttt ctgggagaaa ttgttcgtta atgaccgcct
    27361 ggcgcagtcg ctggccaaca acgatcagaa agccattact gaaaccaccg aacagttaat
    27421 caatgaaccg ctcgatcatc gcggtgaagt ggtgctggtt ggtgcaggtc cgggcgatgc
    27481 cgggctgctg acactgaaag gtctgcaaca aattcagcag gcagatgtgg tggtctacga
    27541 ccgtctggtt tctgacgata ttatgaatct ggtacgccgc gatgctgatc gcgttttcgt
    27601 cggcaaacgc gcgggatacc actgcgtacc gcaggaagag attaaccaga tcctgctgcg
    27661 ggaagcgcaa aaaggcaaac gcgtggtgcg gctgaaaggc ggcgatccgt ttatttttgg
    27721 ccgtggtggc gaagagctgg aaacactgtg caacgcgggt attccattct cggtggttcc
    27781 gggtattacc gcagcctctg gttgctctgc ctattcgggt attccgctca cgcatcgcga
    27841 ttatgcccag agcgtacgct taattactgg acacttaaaa accggtggcg agctggactg
    27901 ggaaaacctg gcggcagaaa aacagacgct ggtgttttat atggggctga atcaggctgc
    27961 aactattcag caaaagctga ttgaatacgg tatgcctggt gaaatgccgg tagcaattgt
    28021 cgaaaacgga acggcagtca cgcagcgcgt gattgacggt acgctcacgc agctgggcga
    28081 actggcgcag caaatgaaca gtccatcgct aattattatt ggtcgggttg ttggcctgcg
    28141 cgataaattg aactggttct ctaaccatta atttaaccag ggccagagaa gtctggcctt
    28201 tttcgtttac aactctcttt ata
//
LOCUS       DAFGPF010000060        27680 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFGPF010000060 DAFGPF010000000
VERSION     DAFGPF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27680
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.060"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            115..402
                     /locus_tag="LSX49_002873"
     CDS             115..402
                     /locus_tag="LSX49_002873"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169262.1"
                     /translation="MNTTLVVLVLAITGALYLPWRLVRDGYKELVQMCLFCSCIVTLA
                     AVYAVLVNLDTPHPFMPMFIAVTAFGAAFVADCALSLWLYQRKANAKTANH"
     gene            457..699
                     /locus_tag="LSX49_002874"
     CDS             457..699
                     /locus_tag="LSX49_002874"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169263.1"
                     /translation="MGNIILMAEKAKGAVDEEAEVYEFEGMDDLIRFRKKFPEKMKYE
                     YHYILSGGTKNFRHIALVEANHFKQFKKLVNQYQDR"
     gene            899..1054
                     /locus_tag="LSX49_002875"
     CDS             899..1054
                     /locus_tag="LSX49_002875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169264.1"
                     /translation="MKKFICNRNGKAVFQEGDRELVAAYQMKSSPVPVTPRKLKAEME
                     AIARTAR"
     gene            1127..1384
                     /locus_tag="LSX49_002876"
     CDS             1127..1384
                     /locus_tag="LSX49_002876"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169265.1"
                     /translation="MCIDHVLTFPVPLEDASLLADYCGFEVYPTYSTNRADETPRFSV
                     VALHRHKARLETLAVADTEKSAHAFRDMAEITAAYYLHFRR"
     gene            1389..1577
                     /locus_tag="LSX49_002877"
     CDS             1389..1577
                     /locus_tag="LSX49_002877"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169266.1"
                     /translation="MNDYLSLMEQARQAEDLRDWKTAAQLYTQAMAVSPKARTMRQRR
                     ERLNLQQRIDFCERNART"
     gene            complement(1619..2389)
                     /locus_tag="LSX49_002878"
     CDS             complement(1619..2389)
                     /locus_tag="LSX49_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="HBL7169267.1"
                     /translation="MIIPTQETYDELQRAYEFFNQRLFESALPPCLITLQREKRTYGY
                     FSNGRFVGRSTGQIVDEIAMNPVYFSIRTIRDTLSTLVHEMVHQLQQHTGKPGRRGYH
                     NKEWAAMMERIGLIPSDTGQPGGKRVGESMSHYIEDGGAFDTACKELLTTEFKLSWLD
                     RFPPHKPTSPTPTGADGKGYVDDEDYEDEGYGDDGELDDEITQALSLVNPPPDTPVNK
                     SNRTKYTCPKCHTNVWGKPGLMLYCGGEHCGKAEYQPT"
     gene            complement(2603..2971)
                     /locus_tag="LSX49_002879"
     CDS             complement(2603..2971)
                     /locus_tag="LSX49_002879"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169268.1"
                     /translation="MEKQPDKLDILMDWFLGDAKEITSKLESVTTSVTETVERLDKAS
                     DEIKKSSEVAKTEVIASQRELVNTLKKEQKVSDQFFERLAGAQTGFSQALIRQILIIT
                     VVCSFVGGALGAAAITFLLH"
     gene            complement(2973..3683)
                     /locus_tag="LSX49_002880"
     CDS             complement(2973..3683)
                     /locus_tag="LSX49_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011279206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StdB protein"
                     /protein_id="HBL7169269.1"
                     /translation="MKIAVMNYSGSVGKTIISSYLLYPRMAGAKFFAIETINMSAADL
                     GVDEVMSLTGDNFGQLVEEIVFEDNAIVDIGASNVERFLSTMTKYEGAIDEFDKYLIP
                     VTPDDKAWQESIKTALALSAAGVPKSKIVLLPNRIKSTPQEDIASVYEWAKDSKKASI
                     HKDAAVFESEIYEYLAYHKISFEELLAEDPETFKAKAKTCTDADERAAAARRYRWMKL
                     ALPVKRNLDRTFEILTAE"
     gene            complement(3696..4130)
                     /locus_tag="LSX49_002881"
     CDS             complement(3696..4130)
                     /locus_tag="LSX49_002881"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169270.1"
                     /translation="MKKDLLLEPRNLAAAVRARLDEIEGLLDKGISRQEIAQILDSEY
                     SFSVTVKALDMALYRARLKRKKGGLHNPESTVNTGSHNPKEQEKAELVETGLHNPEPE
                     KLVEDMGGNKEFLSDTDFKKIGDEAKKVATSFKGSVGNKKGF"
     gene            4617..4964
                     /locus_tag="LSX49_002882"
     CDS             4617..4964
                     /locus_tag="LSX49_002882"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169271.1"
                     /translation="MPSISLRVTEAQKIDLEYRSEGNVSEYIKQQLFGQKESASEVIA
                     RLDKLLERSSSEQQTAGRDRYIEAMLIEVLLILRQVSKADAQKVAGGEIRRLGLEPWS
                     AELAQEREEQSHE"
     gene            4957..6534
                     /locus_tag="LSX49_002883"
     CDS             4957..6534
                     /locus_tag="LSX49_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system DNA-binding
                     domain-containing protein"
                     /protein_id="HBL7169272.1"
                     /translation="MNEADKGKICLGALLFTPLVTWFIAAKTLYGFTPKDARERLVLL
                     IQQTFDLWPLWGALLVGEIIAIIGLIIFFKFNHQIFKGAPFKKIYRGTRLVSQRALAS
                     LTKEREPQITIADIPIPTKAEGTHISIAGATGVGKSTIFAEMMKGCLMRGKMQRVASK
                     KDRMIILDPDGDFLSRFYKKGDKILNPYDARTEGWVFFNEIKSDFDFERFGVSIVPTA
                     KDSQTEEWNGYGRLLFTEVSRKVFNTSRNPTMEEVFYWTNEVPLEELEEYVRGTKAQA
                     LFAGSGRAVGSARFVLSNKLAAHLKMPAGNFSIREWLEDPKGGNLYITWTDEMREALK
                     SLISCWTDSIFSIVLGMSKSNTRKIWTYIDELESLDYLPSLRDALTKGRKKGLRVVTG
                     YQSYSQVISIYGSDVAETLLSNHRTSVVMAAGRLGERTLEFVSKSLGEIEGEREKTGI
                     SRRFGQMGTKNINDDHKRERAVTPTEIATLDDLTGYIAFPGNLPVAKFETHHVNYTRS
                     NPVPGVVLRESTAFAGM"
     gene            6537..9446
                     /locus_tag="LSX49_002884"
     CDS             6537..9446
                     /locus_tag="LSX49_002884"
                     /inference="COORDINATES: protein
                     motif:HMM:NF013601.1,HMM:NF024991.1,HMM:TIGR02686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative relaxase"
                     /protein_id="HBL7169273.1"
                     /translation="MLNITTITRQRVDKVVDYYADGADDYYAKDGNAMQWQGAGAEEL
                     GLTGEVEQKRFAKLLDGKVTDDISVMRKTANSESKERLGYDLTFSAPKGVTLQALVNG
                     DKRIIEAHDRAVTKAIEEAERLALGRFTVNKKTHVENTNKLIVGKFRHETSRELDPDL
                     HTHAFVMNLTKTSDGKWRSLTNDGIVNSLTLLGNVYKSELARELELAGYNLRYDRNGT
                     FDLAHFSQEQIAQFSQRSQQIEAELAKNGLSRETASHEQKNAAALKTRKSKGEVDRDV
                     LYEGWKNRAKELQIDFDSREWKGAANDDIARNTQPAALEKPIEYQADKVMTFAIRSLT
                     ERQSVITERELMDVAMKHGYGRLTLDDIRAARERAITSGNLIKEEATYAAATTNKKQQ
                     NVAMTREQWVTELVKAGRNKDEARKLVDKGITNGRLVQQKPRFTTQLAQQRERNILKM
                     EREGRGKIQTPYTREFSEGWLASRTLKPEQLKAVMGIIHTPNQFISVHGFAGTGKSYM
                     TKSAADFLKEQGVHVTSLAPYGSQVKALQAEGLESRTLQSFLRASDKKIGPGSVVFID
                     EAGVIPARQMEETMRVIRDAGARAVFLGDTKQTKAVEAGKPFEQLIKAGMETAYMKDI
                     QRQKDPELLKAALNAAEGKIKASLTHVTSIVEEKNHDQRYRRIVGDYVAMPPTDRANA
                     LIITGTNDSRKKINAYIQAELGLKGQGINYPLLNRLDTTQAQRQHSKYYEKGAVIIPE
                     RDYSNGLKRGAVYTVLDTGPGNKLTVSDGSGDTIAFSPARFSKLSVYSVEKTELAVGD
                     QVRITRNDAHLDLANGDRFKVKGVQSGEVLLENEKGRLVKIDANKPMYLGLAYASTVH
                     SAQGLTCDKVFINMDTRSLTTAKDVYYVAVTRAKHEAVIYTDDEKKLDKAASREGFKT
                     AALELEQLKRYAKEQQHDAREKGRDKTEPTQEKDNAKRKGKGHDKNNDERAFTSL"
     gene            complement(9724..9918)
                     /locus_tag="LSX49_002885"
     CDS             complement(9724..9918)
                     /locus_tag="LSX49_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169274.1"
                     /translation="MGQGINTLSLVLDNKEALALAQFVKRLTWSDLRGCAVDDDEAYV
                     IKDAVDKLQRAMAEEGFSPR"
     gene            complement(9930..10412)
                     /locus_tag="LSX49_002886"
     CDS             complement(9930..10412)
                     /locus_tag="LSX49_002886"
                     /inference="COORDINATES: protein motif:HMM:NF012792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL7169275.1"
                     /translation="MLDMRLGNSGDIPFIMNLVRDGITSGAFFYAEGNGLETVRSELQ
                     SVTQQYRDNIPVGDYLFVFAEKLTRQPVGFSLLTGRNDFAGRASHLEIRMFAVAADEQ
                     GKGIGKSMLASIIEATPGHRLEASCLPPATKMMRLLAGSGFKLIHETQGGKKTYRFTD
                     "
     gene            complement(10425..10979)
                     /locus_tag="LSX49_002887"
     CDS             complement(10425..10979)
                     /locus_tag="LSX49_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HBL7169276.1"
                     /translation="MIQRLKKRNFLFKAALVAAVLYGASAPSLFAASAQVGFSPEGTA
                     QQLVINVIGSAKDNIRMMAYSFTAPDIMKALIAAKRRGVDVKIVVDENGNTGRASRAA
                     MNLVTNAGIPLRVNSNYKIQHDKVIIVDGRHVETGSFNYTASAEKYNSENAIVMWDAP
                     ELAGQYLKHWQSRWNQGRDFTPSY"
     gene            complement(10942..11973)
                     /gene="virB11"
                     /locus_tag="LSX49_002888"
     CDS             complement(10942..11973)
                     /gene="virB11"
                     /locus_tag="LSX49_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="HBL7169277.1"
                     /translation="MTELTSNIQDIRQRPRREQGVWLTLEPLQRYLSDPDVWELRINK
                     YQQVVCETSKGRIFHDDEKITAEYISRLTDTLCGYNGLPKESVNNVLLPDGSRGIICL
                     PPAVLEGTVAIAFRKHLPVDKSLEQLRDEGRFTGWKRKVQGEVALQPFEQELLELLDK
                     DDLVSFFKIAVRNKLNIVVSGSTGSGKSTFTRSLLREVPYTERIVVSEDVHEIGSDLH
                     HEMVYMLYGDQDGRLAPAVSLKACMRLSPDRIMMTELRDDAAWDYINSLNTGHPGGIT
                     STHADDAKSTFSRIALLIKQTGVGQTLDYDVIMKTLYTTIDVVVYMEHRQIVEVLYDP
                     AFKKAQLSL"
     gene            complement(11966..13120)
                     /gene="virB10"
                     /locus_tag="LSX49_002889"
     CDS             complement(11966..13120)
                     /gene="virB10"
                     /locus_tag="LSX49_002889"
                     /inference="COORDINATES: protein motif:HMM:NF038091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein VirB10"
                     /protein_id="HBL7169278.1"
                     /translation="MRKDREENLDYLDEEDTGIEDERQGFSGSPKKRIAGARAFVGLM
                     VLIGSAMVGWFIYNQMHVKKLADDPKKDKEQVMTSSLPRQSFDDVPPTIDNTPKNSVV
                     PPLQTTQEPQQQVARQTLNNQKKELSPEEKIMRARLGVSFNGVDPEKQATTAKEQERR
                     SGQDNTETSSNSQALASRMKPARMAVAQASVMPHPNLTIAQGTMIPCGTNTELDTTVP
                     GQVKCTVSRDVYSADGTVKLIDKGAVVTGEQNSGIQNGQNRVFVLWSRLRNPDQTIVN
                     LDSSGTNALGSAGVPGQVNSHFWERMGDAIFFSVLTDGMKAGIASINNNNSDVTFNTT
                     ENSTDQLATEALRAKINIPPTLYAAQGDAVSIYVARDLDFSTVYGLEMND"
     gene            complement(13117..14004)
                     /locus_tag="LSX49_002890"
     CDS             complement(13117..14004)
                     /locus_tag="LSX49_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="HBL7169279.1"
                     /translation="MKKQLIAGLILVSLGLSGQALALEVGKGSPYDYRIKSVVYNPVD
                     VVRIDSVAGVATHIVVAPDESYVTHAFGDSNSYAFTHVENNMFIKPKGEVPSDTNLVL
                     VTNKRTYNIVLHYVGDYTTKDAQGNVKANFIKTPWSMKNATLQLTYLYPFEDMKKANK
                     TLESNRVKKALKDLQNGPYNLLYKMSDEDEYRTVAPVNVWDNFRFTYFKFPANADLPV
                     VFYIGDDGKEHTVNQHPAGEYNNIVVAETVAKEWRIRYGNKVVGVLNMNYNPNLGAIS
                     TGTTSPDVKRVKKGEGDKS"
     gene            complement(14007..14720)
                     /locus_tag="LSX49_002891"
     CDS             complement(14007..14720)
                     /locus_tag="LSX49_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004216210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HBL7169280.1"
                     /translation="MKKNKHQAISREDLNKYHEETQGLERDMVNEILNSRSRAWKIAT
                     AFFVFAVVSMITAVGVIIRFAQPLPAYLTTINKDTGEVSQVKITRDEATYGDVIDQYW
                     ISQFVIHRESYDYNSIQVDYDAMSLMASGDVADEYLSMFKGPNRIDKRLGDSERTTVH
                     INSVITDREHGVATVRFTTQQRIRQRPNPEPPRYWIATIAYEYKALPMTAQQRYINPL
                     GFRVTSYRKNAENVGAVGG"
     gene            complement(14726..14896)
                     /locus_tag="LSX49_002892"
     CDS             complement(14726..14896)
                     /locus_tag="LSX49_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169281.1"
                     /translation="MVHFFKYTAMALIGLLLAACSSSPTPPPEPNMKKLVDVNKTYPA
                     ELYRADAANNGE"
     gene            complement(14991..15998)
                     /locus_tag="LSX49_002893"
     CDS             complement(14991..15998)
                     /locus_tag="LSX49_002893"
                     /inference="COORDINATES: protein motif:HMM:NF016491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HBL7169282.1"
                     /translation="MDTVTKEFVASNLGIVISTISPVIGLALICKLTLDGLFTLARPH
                     GEPLSSLIKKFIVWSMIISFASAGGLYQTQLADAAMKIPDEFSSVLVINGSSGGTEDA
                     MGNNIDKAIHDGMQVARTAFDNADIYSGSGLASLFLACAVIISTVLICGIGAGLVLMA
                     KLLLAITVCFGPIFIFCLLFKPLYGMFNKWLGSMVNYGLVTVLLSMLFGLMIKFYQKA
                     LDAVTASGADSSLLGPVFACLLIMIVSYLILMRVPEIASRWGDGISAGIQELIPSPGG
                     GGSRGGQNAVNNQGGGAKGGAGTGNGAKTAAATAAGGPGAGAATAAGSQMQGFAKGSR
                     R"
     gene            complement(16053..16289)
                     /locus_tag="LSX49_002894"
     CDS             complement(16053..16289)
                     /locus_tag="LSX49_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="HBL7169283.1"
                     /translation="MKKLILPLALFLLAGCDSEHPVSWYKEHDQERKAMVEKCRDDAA
                     LKVKPDCQNALEAEKDLKVFGKSDDGLSMPKVTP"
     gene            complement(16293..17000)
                     /locus_tag="LSX49_002895"
     CDS             complement(16293..17000)
                     /locus_tag="LSX49_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HBL7169284.1"
                     /translation="MKKTLVSLVLALAISPVAVNAQLVVNDPANLAQALEQVTLMTQQ
                     IEQLKSQLLKQEQTLASLTGSSGIGNLLNGDISTLKGNLPSDWTQVYSDAMNSSSGIT
                     SSAQSMLKEFQSQIDGMNRSEAMSFIKQKLAEKGAYDRVMAQNAYNNEMAELNNIQEL
                     TNQIDSTTDMKQIADLQARIQTAQGAIQGEQTKLQLMAMLQTSQDKILQEQKQYAQKR
                     FVLGADGEDLSMPNVTE"
     gene            complement(17010..19640)
                     /locus_tag="LSX49_002896"
     CDS             complement(17010..19640)
                     /locus_tag="LSX49_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="HBL7169285.1"
                     /translation="MAVAEMQKGGVKDYKKEPSSLKYIPYSYHVTPHVISTVNGEYLS
                     IFKIRGRTHDCASDAELIKWHADLNQLLKGIGSEHVKLWTHLHHREINNYPDTHYNMT
                     FPRMVNEYYRDQFDDTPMMVNDLYLTVVYNPVGDSAQKMLAKFDKPSPNELREMQVDA
                     LSALEDICEQVMNSMRPYGIDRLGYYFRDKRGNIIPEQKKDDAEDDEDIIDLREDLLA
                     DVEYQDVQADKEAFSGTQHTFSKALEWLYYLVNGEWAPVPVCRGRIREYLVTTRPTSS
                     LWGDGIEIRGTDERRYTSAVEIRDYDSDTEPGQINILMEAPFEFVLTQTYCCMSQQAA
                     RTYLTNQQKALLETGDPSYTQINQMTDAVDGVVSRTFIMGWHHLTVHTFGKSLKEARS
                     NAGVAKNMLNNCGLIASQVGLASEAAYYAKLPANQHLSPRPCPLNSWNFLCFSPFHNF
                     MSGKANNNPWGPALTLFKTVANTPLYMNLHVTPEDELSFGKRPLAHTLMLGRSGAGKT
                     TLLNFLLTQAMKYNPRIFAFDRDQGMMPMIKALHGHYTVLKEGVASGWAPLQMPGTKV
                     NIAFCKRLMRLCAEITKGSVLDADQVNDLNRAVDALMDENSLIPTDLRTVDMLIQQMP
                     NPYQTAGSKQTLASLLVPWTRGHENGWLFDNDSDSLNLGEYDIYGFDLTDFIVADNEI
                     PPATRTPLLMYLNFRVRQSIDGRRRVIQVFDEFHQYLDDPIMSVEVKRGLKTDRKKDA
                     VYVFSTQEPNDALDSSIGKTIMQQCVTKILLENPDADYEDYVTRLKLTPAEFDALLSI
                     PENSRQFLVKQGSQSAMAQFNLAPRVKTPENFRKLDKILSILSGETQNAETLAKIIEQ
                     IGDDNPDKWLEPYWKSVLAA"
     gene            complement(19640..19954)
                     /locus_tag="LSX49_002897"
     CDS             complement(19640..19954)
                     /locus_tag="LSX49_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="HBL7169286.1"
                     /translation="MNLSGKYPLFKGATRLPTFAGVPRTVIIATFIFCATLFMTIHLW
                     AIVLFGLLWFIEFCISKHDDRMFRIIWLAIMTKGLNMINSPFTKLWGGSSYSPTDYGD
                     KK"
     gene            complement(20007..20297)
                     /locus_tag="LSX49_002898"
     CDS             complement(20007..20297)
                     /locus_tag="LSX49_002898"
                     /inference="COORDINATES: protein motif:HMM:NF016820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HBL7169287.1"
                     /translation="MNTAIKRFFPVAMFMMVALCVPELALAAGADTGESSMSSINSWL
                     MTWIPIAATVLIIVSAIAWIAHMLPASWAVRIVVGLIVVGSASFLVGLFGLS"
     gene            complement(20281..20598)
                     /locus_tag="LSX49_002899"
     CDS             complement(20281..20598)
                     /locus_tag="LSX49_002899"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL7169288.1"
                     /translation="MRVYLILLKQLEEVFNQNKVVRIAIQRMDKKKWIPLFDVKNSEG
                     GVITCSLRVQSGEGVRTWADLRILADMLRDDFNAREVGLFLDEPDFIFPDDGVLDKDE
                     YSD"
     gene            complement(20621..21361)
                     /locus_tag="LSX49_002900"
     CDS             complement(20621..21361)
                     /locus_tag="LSX49_002900"
                     /inference="COORDINATES: protein motif:HMM:NF013618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBL7169289.1"
                     /translation="MKQVVALFPLLIAGLLDATPANAELSAPVMALAKRCAPEVHPLT
                     IGYLVSHESRNNPYAINVNVPKGTKSPLARQPRSLDEAVKTTKWLTAHGYNFDVGLGQ
                     INSANFPKLNVSAADLFNGCKNLEAAQYVLNYCYQLATKEYAPGQSALRHALSCYNTG
                     SLTAGFTNGYVSKVVAQIGQSKPVIPALKADDGSTDVESVDTAIDAVPVDAADGEEQP
                     KDAGMTDAFGGSDKDAFGASDGDAFRQK"
     gene            21424..21660
                     /locus_tag="LSX49_002901"
     CDS             21424..21660
                     /locus_tag="LSX49_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000960954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS histone family protein"
                     /protein_id="HBL7169290.1"
                     /translation="MSRQDEKKHKTEQERETSVPKRKIIFVPLQSEKSPKGEPRYRDP
                     ANPFNTWVGRGKRPDWLKKYLDEGRELSEFEIAE"
     gene            21672..22109
                     /locus_tag="LSX49_002902"
     CDS             21672..22109
                     /locus_tag="LSX49_002902"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169291.1"
                     /translation="MSKIIDFPTGKKREKRAKAIRARRNKEAQQRSEITPSKFWWVKK
                     IKLLTVIKQSARFLLLHLGLLVADILICLLLILGKLLKIFTMIGIIAALLFLVVEYRN
                     DWHYTQSALHAAAIFVSLIALRIGHDKLLNGLIRLKSHLSRKG"
     gene            22115..22432
                     /locus_tag="LSX49_002903"
     CDS             22115..22432
                     /locus_tag="LSX49_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169292.1"
                     /translation="MRKIIIASVVILASSYSVASFAKDPCKTLACMAAKSGGQFGSIG
                     DSDCSGAIADFFNIVKKNKHGFLPNHTADARKEFLMECSGAEQNTAAVSRVISMFGRI
                     RKG"
     gene            22435..22749
                     /locus_tag="LSX49_002904"
     CDS             22435..22749
                     /locus_tag="LSX49_002904"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169293.1"
                     /translation="MKTKSIIFTAALLLTGCASQSQVDQLTKQVNTLKTDLYNLQIQQ
                     RNDTQALQREVQKSRPIGVCYLDGQPYSQGAVIAGRICASNGVIVNGKPTEVSWQVYH
                     RR"
     gene            22797..23434
                     /locus_tag="LSX49_002905"
                     /pseudo
     CDS             22797..23434
                     /locus_tag="LSX49_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000893479.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            23616..23852
                     /locus_tag="LSX49_002906"
     CDS             23616..23852
                     /locus_tag="LSX49_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014354012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169294.1"
                     /translation="MKFIESIKDKENLQKKYLMRFRRCSSLDTLEKVFDSLRDKLSGK
                     ELDAMMSASDHRRAEITHNTLWDKVPASAWRNVK"
     gene            complement(23912..24226)
                     /locus_tag="LSX49_002907"
     CDS             complement(23912..24226)
                     /locus_tag="LSX49_002907"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169295.1"
                     /translation="MSDKQEINDVAIVKWVFGIIFAVVIIGMPTLGFFKFVMLLISLT
                     ITIGTVFYFGSITKNKDNKIPMMILGGFVGIIISAGLVLYNVHERNEMCSSDFVPVFC
                     SL"
     gene            complement(24252..24578)
                     /gene="mazF"
                     /locus_tag="LSX49_002908"
     CDS             complement(24252..24578)
                     /gene="mazF"
                     /locus_tag="LSX49_002908"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HBL7169296.1"
                     /translation="MKRDYIPDAGDIVWMDFDPQAGHEQAGHRPALVLSPAVYNGRIG
                     LLLCCPMTTKIKGYPFEVRNGEGSAVLADQVKSLDWRERGAVKKGKVSAAVLAEVRSK
                     LKVLIG"
     gene            complement(24568..24825)
                     /locus_tag="LSX49_002909"
     CDS             complement(24568..24825)
                     /locus_tag="LSX49_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169297.1"
                     /translation="MLKFLKKVYSYLEFLGALIWVGVGLYSIWLGFSKLFKDNSFSIG
                     GVEVVSLLDTTPVAIMFIFCGVIIIAFIWVGYISKRLNNEA"
     gene            complement(24834..25376)
                     /locus_tag="LSX49_002910"
     CDS             complement(24834..25376)
                     /locus_tag="LSX49_002910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169298.1"
                     /translation="MKKEDRSFIRWVSLSCKIFTAALAIGVVCYAVMGVLGLVNNPVP
                     YYFSEWINWMQPKLKLPVTYHDSSLYLDNGTYSIGDYILSVGYLFVIIMAQSYAAAYF
                     LGRLNHTLISKVIMYKATKEFHQKYSGIKAAHFERLLSENLTETGLEDVSRKHWEKWR
                     EHYKSNMSYDEWKQKFKKVL"
     gene            complement(25376..25621)
                     /locus_tag="LSX49_002911"
     CDS             complement(25376..25621)
                     /locus_tag="LSX49_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBL7169299.1"
                     /translation="MTQVIIKKWGNSPSVRLPSAIVKAASLNVDDVVELSVEDGAITI
                     VPVKTKEYSLDALMAGVTNENIHEEISFGAPVGKELL"
     gene            complement(25653..25859)
                     /locus_tag="LSX49_002912"
     CDS             complement(25653..25859)
                     /locus_tag="LSX49_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169300.1"
                     /translation="MFGLMFHIMFGIVFIVMSVASLVGLVLHGHEYTPGHFGNMTALC
                     IASTLAWVWALSAAKEAWYILKSR"
     gene            26073..26657
                     /locus_tag="LSX49_002913"
     CDS             26073..26657
                     /locus_tag="LSX49_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL7169301.1"
                     /translation="MKIGYARKSTKEQDTSLEYQIEALQKAGCEKWYAEQVSRGGNKR
                     LKTGTPELENCLKALRAGDTLVVWALDRLGGTLLQLLQLMNELRSKGIHFESLKERID
                     TQSPMGEMYYSLIAIFSNFEVARNHERTMAGLAAAKKKGRIGGRKPKLSPQDIKEINA
                     LVKSPEITVKEIAARFKVSRPTIYRHITPDSNTD"
     gene            26690..27574
                     /locus_tag="LSX49_002914"
     CDS             26690..27574
                     /locus_tag="LSX49_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL7169302.1"
                     /translation="MTDKPLPAKQIKTVNTGIAIKENPPKGDDMAFTHSILCQVGLPR
                     SKVDGREFMRKSGDAWLVVQAGWLDEGSGPVEQPIPYGSMPRLALAWVSSYALRKKTR
                     EIPIGKSANEFLQLMGLSGGGRQYKTLREQMHALAACRLQLGFKGRSFNGQPVEQFDA
                     WQKDDQSGQLSLWPGVMTLSEGYFNGLIDSAVPLDNRALYGLKGSALSLDVYTWLAHR
                     LHRIEGRPIKLHWMNLREQFAQEYMGKDPDKDFKKKFLPALRDVLTVYPQAKVEKVTG
                     GILLYPSPPPIPFKEAKK"
BASE COUNT         7532 a         6796 c         6374 g         6978 t
ORIGIN      
        1 aaaagttgac ttttaagggg ggaaagccta tactttattt acggttagca atggtgctga
       61 ccggcccgga accagcggcg gcaaccgctc cgggcaacct gcgaaggaaa atgtatgaat
      121 acgactcttg ttgttttagt cctcgccata acaggcgcgt tatatctccc ctggcgtctt
      181 gtgcgcgacg gttacaaaga actggtgcag atgtgcctgt tttgctcctg tatcgtcacg
      241 ctggccgctg tatacgccgt gttagttaat ctcgatactc cacacccgtt tatgccaatg
      301 tttatcgcgg taacggcgtt cggtgcggca ttcgtggctg actgcgcttt atctctctgg
      361 ctctatcagc gtaaagctaa cgctaagacg gctaaccact aaccactaat taaaccgccc
      421 tgcggggcgg tttctaacca tgatacgggg gtaaatatgg gaaatatcat cctgatggcc
      481 gagaaagcaa aaggcgcggt tgatgaagag gctgaagtgt atgaatttga gggaatggat
      541 gatctgatcc ggtttcgtaa gaaattccct gaaaagatga aatatgaata tcattacatc
      601 ctttccggcg gcacgaaaaa ttttcggcat atcgcgcttg ttgaagccaa ccattttaag
      661 cagttcaaaa agctggttaa tcagtaccag gatcgttaac gttgaacagc gcggtaatgc
      721 cgcgctgttt tttatggagt tctggcgctt tgcgtcattt gagcgctttt acatgtatct
      781 ggagatatac aataaaagta ttatattatg atactttaag ttgacttttt ggggtgagga
      841 aattatactg tttttatcgg ttagcaatgg tgctgaccgt aagcgaagga gcaaggttat
      901 gaaaaaattt atctgcaacc gcaacggcaa ggcggttttt caggaaggtg atcgggagct
      961 ggtagccgct taccagatga aatcctctcc ggttccggtg acaccccgca agctgaaagc
     1021 tgaaatggag gctatcgcca gaacagcccg ataatcaatc acccgcgcca acggcgcggg
     1081 tatccctcat agcggcggca accgcttttt gcgaaggagc aacgcgatgt gtattgatca
     1141 cgtcctcacc tttcccgttc ccctggaaga tgccagcttg ctggcagact actgcgggtt
     1201 tgaagtgtat cccacctaca gcacgaaccg ggccgatgaa acgccccgtt tttccgtggt
     1261 ggcacttcat cgccacaaag ccaggctgga aacgttagcc gtggccgaca cggagaaaag
     1321 cgcccatgct ttccgcgata tggccgagat taccgccgct tactacttac attttcggcg
     1381 gtaatacgat gaacgattat ctatccctca tggaacaggc acgacaggca gaggatttgc
     1441 gcgactggaa aaccgccgcg cagctctaca ctcaggcaat ggccgttagt ccaaaagcca
     1501 gaacgatgcg ccagcgccgc gaaaggctga acctacagca gcgtatcgac ttttgcgagc
     1561 gtaacgcgag gacgtaaaaa ctaaaaaaaa accgcctcat acggcggttt ttttctggtt
     1621 aggttggctg gtattctgcc tttccgcagt gttcgccgcc acagtacagc atcaggcccg
     1681 gctttcccca cacgttcgta tggcatttcg ggcaggtgta ttttgtccgg tttgatttat
     1741 tcaccggcgt atctggcggc gggtttacca gcgaaagggc ttgtgtgatc tcatcatcca
     1801 gctcgccatc gtcgccgtat ccctcatcct cataatcttc gtcatcgaca taccctttac
     1861 cgtctgcgcc ggttggcgtt ggtgacgttg gtttgtgtgg cgggaaccga tccagccaac
     1921 tcagcttaaa ctccgtggta agcagctcct tgcaggcggt atcaaacgcg ccgccgtcct
     1981 cgatgtaatg gctcatggac tcaccgacgc gcttacctcc tggctggccg gtgtcggatg
     2041 gtatcaggcc gatgcgctcc atcatcgccg cccattcttt attgtggtat ccacggcggc
     2101 ccggtttgcc ggtgtgttgc tgcaactggt gaaccatttc atgcacaagc gtggaaagcg
     2161 tgtcgcgtat cgtgcggatc gagaaataga ccggattcat ggcgatttcg tcaacaattt
     2221 ggccggttga gcgaccaaca aagcgaccat tcgagaaata gccatacgtt cgtttttcgc
     2281 gctgaagggt gataaggcaa ggcggcagcg cactttcaaa caggcgttga ttgaaaaatt
     2341 cgtaggcgcg ttgaagctcg tcgtaagttt cctgggtagg gatgatcata gcggcctcac
     2401 attgggtttc tggattgcac aaaccatttt attgattatg gattgtgcaa tccactttta
     2461 tttttgggcg ttccctgcgg gcgggctttc gtgctgcgca tcgagccagg caagctgtct
     2521 cgccccttcg ggcgtcaatc cctaacgcaa tcgaggccaa aaaaaacggc ccggataggg
     2581 ccgcttcagg tcaggctttt tgtcagtgaa gcaggaacgt tatagccgcc gcgccgagcg
     2641 ctccaccaac gaaggaacag acaaccgtga taatcagaat ctgcctgata agcgcttgcg
     2701 aaaaccctgt ttgcgccccg gccagacgtt caaaaaattg gtcgctaacc ttctgctcct
     2761 tcttcagagt gttgaccagc tcgcgctggc ttgcgatcac ttctgttttc gccacctcag
     2821 atgatttctt tatttcatcg gaggctttat ccagccgttc tactgtttcg gtaacgcttg
     2881 tggttacgct ttccagtttt gaggtgattt ctttcgcatc gcctaaaaac cagtccatca
     2941 ggatatctaa tttatcaggt tgcttttcca tattattcag ccgttaatat ttcaaaggtg
     3001 cgatcaagat tacgtttaac cggtaatgct aatttcatcc agcgataacg acgcgcagcc
     3061 gccgcacgtt catcggcatc ggtgcaagtt ttagcttttg ctttaaaggt ttctggatct
     3121 tctgccagca gttcttcaaa cgaaattttg tgatacgcga ggtattcata aatttcactt
     3181 tcaaaaacgg cggcatcttt atgaatagag gcttttttag aatctttcgc ccattcatat
     3241 accgaagcaa tatcctcctg cggagtcgat ttaatgcggt taggcagaag aacaatttta
     3301 gatttaggaa cgccagcggc acttaacgcg agggcggtct taatactttc ctgccatgct
     3361 ttatcatccg gggtgacagg aatcagatat ttatcaaatt cgtcaattgc accctcatat
     3421 tttgtcatgg tagaaagaaa ccgctcaacg ttcgacgcgc caatatccac gatggcatta
     3481 tcttcaaata cgatttcttc aacgagttga ccaaagttat cgccggttaa gctcatcact
     3541 tcatcaacac ccaaatccgc agccgacata ttgattgtct cgatggcaaa gaatttagcg
     3601 ccagccatgc gaggatacag caggtatgac gaaataatgg ttttgccgac gctgccactg
     3661 taattcatta ctgcaatttt catctgtaag ctcctttaga aacctttctt attacctacg
     3721 ctacctttga atgaggttgc gactttcttt gcctcatcac caattttttt aaaatcggta
     3781 tcggataaaa attctttgtt cccgcccata tcctcaacta atttttctgg ttctggattg
     3841 tgcaatccag tttccaccag ttccgctttc tcctgctctt ttggattgtg cgatccagta
     3901 tttaccgtac tttctggatt gtgcaatcca ccttttttgc gtttcaatct tgcccggtac
     3961 aaagccatat ctaacgcttt cacagtcaca gaaaagctgt attcactatc aagaatttga
     4021 gcaatttctt gcctactaat acccttgtct aacaaacctt caatctcatc aagacgcgct
     4081 cttacagccg cagcgagatt gcgaggttcc agtaaaaggt cttttttcat accacccccg
     4141 cttgtcgaat ttcactatat ggcagccagt tttagctgtc aatcggtttt tgtagtattt
     4201 cggtagtatt cctgtagtaa ttcagtagta acgcttgtcg ataccgctca tttttgtagt
     4261 atatcagtag tatatctgta gtaatggcta tttcagtttg tagtatttta gtagtaattc
     4321 agtagtatcg gtgtagaaaa ctttcatgca agcatgaaag tggtgaatgt gaacgctttt
     4381 tgagcgctta atgcgtgtgt aagagctgtt tctcccttaa aaaaggcgtg ttatggtatc
     4441 ccttaatggc tatacaccat acgcaattac gattttcatc gtaaatgctt gaaaacaaaa
     4501 caaattattc taatttgtgt tttaatatgt aatacacagc gtattacata tgtggaatta
     4561 agccgcatct atgctagatt tgtatgtatt acatcggtat tacacaaagg aaacctatgc
     4621 catctatcag tttaagagtg accgaagcgc aaaaaatcga ccttgaatac cgttcggagg
     4681 gcaacgtatc ggagtacatc aagcaacagc tttttggaca aaaagagagt gccagtgaag
     4741 tgatcgcccg gcttgataaa ttgctggaac gttcatcttc agagcagcaa accgccggac
     4801 gagatcggta catcgaggca atgttgattg aggtgttatt gatacttcgc caggtgagta
     4861 aagcagatgc gcagaaagtt gccggtggtg aaattcgccg gttagggctg gagccgtggt
     4921 cagcagagct ggcccaggag agagaggaac agagtcatga atgaagcgga taagggtaaa
     4981 atttgcctgg gggcattgct ttttaccccc cttgttacgt ggtttatcgc ggcgaaaacc
     5041 ttgtatggtt ttacgccaaa agatgcgcgt gaacgtctgg ttttacttat tcagcagact
     5101 tttgatttat ggcctttatg gggtgcttta ttagtcggtg aaattattgc catcataggc
     5161 ttaatcatat ttttcaaatt taatcaccag atatttaaag gtgcaccatt taagaaaata
     5221 tatcgtggta cgcggcttgt ttctcagcgg gctttggctt ccctaactaa agaaagagag
     5281 ccgcaaataa caatcgctga tattccaatc cctacaaaag cggaaggtac acatatttca
     5341 atagccgggg cgaccggtgt tggtaaatca acaatctttg ctgaaatgat gaaaggttgc
     5401 ttgatgcgag gcaagatgca gcgggttgcg tccaaaaaag accgcatgat aatcctcgat
     5461 ccagatggcg attttctttc tcgtttttat aaaaaaggcg ataagattct aaatccatat
     5521 gatgccagaa cagaagggtg ggtatttttc aacgaaataa aaagtgattt tgactttgag
     5581 cgattcgggg tttctatcgt acctacagcg aaggattcgc aaacagaaga atggaatgga
     5641 tacggtcgcc ttttatttac cgaggtatcc cgtaaagtat ttaacaccag tcgaaatcca
     5701 acgatggaag aagtctttta ctggacaaat gaagtgccac tagaagaact tgaagaatat
     5761 gtcagaggta ctaaagcaca ggctttattt gctggtagcg gtcgggccgt tggtagtgct
     5821 cgctttgtgc ttagtaataa acttgccgcc cacctgaaaa tgccagcagg aaacttctct
     5881 attcgtgaat ggctggaaga tccaaaaggc gggaatttat atatcacctg gacggatgaa
     5941 atgcgtgaag cactgaaatc gcttatttca tgctggacag atagcatatt ttctattgtg
     6001 ttaggtatga gcaagagcaa tacccgtaaa atctggacgt atatagatga actggaatcc
     6061 cttgattatc tgccatcatt acgtgatgcg ttaacaaaag gccgtaaaaa aggactacgg
     6121 gttgtcactg gttatcagtc gtattcacag gtcattagca tctatggcag cgatgtagct
     6181 gaaacccttc tatctaacca tcgtacatcg gttgttatgg ccgccggtcg cctgggtgaa
     6241 agaaccctcg aatttgtctc taaatcgttg ggggagattg agggcgaaag agagaaaacg
     6301 gggattagcc gccgctttgg tcaaatggga accaaaaata tcaatgatga tcacaagcgc
     6361 gagcgggctg taacgccaac cgaaatcgcc acgctggatg atctgaccgg ctacatcgcg
     6421 tttcccggaa atctgccagt ggctaaattt gagactcatc acgttaacta cactcgttcg
     6481 aaccctgtac cgggcgtggt cttacgtgaa agcaccgcat ttgcaggaat gtaaacatgc
     6541 tgaacattac gactattacc cgtcagcgtg tcgataaggt tgtcgattac tatgctgatg
     6601 gcgcagacga ttactatgcg aaagacggta acgcgatgca gtggcaaggc gctggcgcgg
     6661 aagaactggg cttaaccggc gaggtagaac aaaaacggtt tgcgaaattg cttgatggca
     6721 aagtaacgga tgatatttcc gtgatgcgta aaacggccaa cagcgaaagc aaagaacgat
     6781 tgggatacga tcttacgttt tccgcgccga aaggcgttac gcttcaggca ctggtcaacg
     6841 gtgataaacg tatcattgaa gcgcacgatc gggcggtcac taaagccatc gaggaagcgg
     6901 aacggctggc actaggtcgc tttaccgtca ataaaaaaac gcacgttgaa aacacgaata
     6961 agctgattgt cggcaaattt cgacatgaaa cgtcacgcga gctagacccg gatttgcaca
     7021 cccatgcctt tgtaatgaac ctcaccaaaa ccagcgatgg taaatggcgt tcgctcacga
     7081 atgacggcat tgtgaactcg cttacgttat tgggtaacgt ttacaaatcc gagctggcaa
     7141 gagagctgga gctggccggt tacaacctgc gttatgatcg gaatggtacg tttgatttgg
     7201 cgcatttcag ccaggagcag atagcccaat tcagccagcg cagccagcag attgaggccg
     7261 agttagcaaa gaatggttta agccgtgaaa cggccagcca tgagcaaaaa aatgcggccg
     7321 cgctgaaaac tcgtaaaagc aaaggcgaag tagatcgcga tgtactctat gagggctgga
     7381 aaaaccgcgc caaagagctt cagattgatt ttgatagccg ggagtggaaa ggtgcggcca
     7441 acgacgatat agcgcggaat acgcagccag cggcgctgga aaagcctatc gagtaccagg
     7501 ctgacaaggt aatgaccttt gccattcgct cacttaccga acgtcaatcg gtgattaccg
     7561 agcgggagct gatggacgtg gcgatgaagc atggctatgg ccgcttaacc ctcgatgata
     7621 ttcgggctgc gagagaacgg gccataacct ccggcaacct catcaaagaa gaagcaacat
     7681 acgcagcggc cacgaccaat aaaaaacagc agaacgtagc aatgacccgc gaacaatggg
     7741 taacggaact ggtgaaagct ggccgcaata aagatgaggc ccgtaaactc gtagataagg
     7801 gcatcacaaa cgggcggctg gtacagcaaa agccgcgttt taccacacag ttagctcaac
     7861 aacgcgaacg caacatactg aagatggagc gggaagggcg cggaaagatc cagaccccat
     7921 acactcgcga gtttagcgag ggctggttag ccagcagaac gttaaaaccc gaacagttaa
     7981 aagcggttat gggaattatt cataccccca accagtttat ttctgtacat gggtttgccg
     8041 gtactggcaa aagttatatg accaaatcgg cagcggattt tctaaaagag cagggcgtac
     8101 acgtcaccag tcttgccccc tacggtagcc aggttaaagc gcttcaggct gaagggctgg
     8161 aatctcgcac actccagtct ttcctccggg cctcagataa aaaaattggc cccggctcag
     8221 tagtttttat tgacgaagca ggggtaatcc cggcccgcca gatggaggaa accatgcgcg
     8281 tgatccgcga tgcgggcgca cgagcggtat tcctgggcga taccaaacag actaaagccg
     8341 tcgaagcggg taaacctttc gagcagctta ttaaagccgg tatggaaacg gcctatatga
     8401 aagatattca gcgccagaaa gacccggaat tgctgaaagc cgcgctaaat gcagcagaag
     8461 ggaaaataaa ggcgtcgttg acccacgtaa ccagcatcgt agaggaaaaa aatcatgatc
     8521 agcgctaccg ccgcattgtc ggggattacg tggcaatgcc gccgacagac cgggctaacg
     8581 ccctgatcat caccggcacg aacgacagcc ggaaaaaaat taatgcgtac attcaggccg
     8641 agctggggct aaaaggccag ggtatcaatt acccgcttct gaaccgtctt gataccactc
     8701 aggcccagcg gcagcacagc aaatattacg aaaaaggagc cgtgattatc ccggaacggg
     8761 attacagcaa cgggctgaaa cgcggggccg tttatactgt tctcgatacc ggccccggca
     8821 ataaacttac ggtaagcgac ggcagcggcg acacaatcgc attttcaccg gcgcgatttt
     8881 ccaaattatc cgtgtactca gttgaaaaaa cggagctggc cgtaggcgac caggtaagga
     8941 tcacccgtaa cgatgcgcat ctggatttag cgaacggcga ccgttttaag gtaaaaggcg
     9001 tccagagtgg tgaggtactg ctggagaacg agaaagggcg actggtaaaa attgatgcca
     9061 ataaacctat gtatttaggg ctggcttacg cttcgaccgt tcatagcgct caggggctaa
     9121 cctgcgacaa ggtttttatc aatatggata cccgatcact cacaacggcc aaagatgttt
     9181 attacgtggc tgtcacccgc gctaaacacg aagccgtcat ttacacagac gatgagaaga
     9241 agctggataa agcggccagc cgtgaagggt tcaaaaccgc cgcgcttgag ctggaacaac
     9301 tcaaacgcta tgccaaagag cagcagcatg atgcccgcga aaaaggccga gacaaaaccg
     9361 agccgacgca ggaaaaagac aatgccaagc gtaaaggcaa aggccatgac aaaaataacg
     9421 acgagagagc atttacctcg ctctaactga ctaatccccc gaacagcacc ggcagaacaa
     9481 acccaccccg gattattggg agccggtatt gtccggggtg cactatcgta gcatttgtgt
     9541 tgcatacatc ccgtaaaaac tcattcagtg aacctgaaca accggttgtg tggccacgtc
     9601 gccggcagca gctggccaac gctggcgccg aaaacgcgaa gtgaataaaa acataaagtt
     9661 atgaggggag gggataagaa aagggcattc aaaaatttcg atgccctttt gtggaaacct
     9721 gcgctatcgc ggggaaaaac cttcttcggc cattgccctc tgtagtttat cgacggcatc
     9781 cttgatgaca tacgcctcgt cgtcatcaac ggcacacccc cgtaaatcac tccacgtcag
     9841 gcgcttaaca aactgcgcca gtgccagcgc ttctttgtta tccagcacta aagacaacgt
     9901 gttgatacct tgacccataa cccacctcgt tagtctgtaa agcggtacgt tttcttaccg
     9961 ccctgcgttt catgaatcag cttaaacccg cttccggcca acagtctcat catttttgtg
    10021 gctgggggga gacaggaggc ttccagccgg tgtccgggcg tggcttcgat gattgaggca
    10081 agcatactct tgccaatgcc tttaccctgc tcatcagccg caacagcgaa catacggatc
    10141 tcaagatgag atgcccggcc cgcaaaatca ttgcggccgg ttaacagcga aaatcccacc
    10201 ggctgccgcg ttaacttctc ggcaaagaca aagagataat ccccaacggg gatattatct
    10261 ctgtattgtt gggtgacact ttgtagctca gatctcaccg tttcaagacc gttaccctcg
    10321 gcatagaaaa atgcgccaga tgttatcccg tcgcgcacca ggttcatgat gaaaggaata
    10381 tcgccgctgt ttcctaatcg catatcaagc atatcattct ccattcaata agacggggta
    10441 aaatcccggc cctgattcca gcgtgattgc cagtgcttca ggtactgccc ggccagttct
    10501 ggcgcatccc acatcacaat cgcgttttca gagttatatt tctcggcact ggccgtgtag
    10561 ttaaaactgc cagtttccac atgacggcca tcaacgatga tcaccttgtc atgctggatt
    10621 ttgtagttac tgttaacccg aagcggaata cccgcgttcg taacaagatt cattgccgca
    10681 cgacttgcgc ggcccgtatt gccattctca tcaacgacaa ttttcacgtc tacaccgcgg
    10741 cgtttggccg caatcagcgc tttcataata tcgggggcgg taaagctgta ggccatcatt
    10801 ctgatgttat cttttgccga gccgattacg ttgataacga gctgctgcgc ggttccttcc
    10861 ggcgagaaac ctacttgcgc cgatgcagca aaaagagacg gggccgaagc cccgtaaagt
    10921 acggcggcaa ccagtgccgc tttaaagaga aagttgcgct tttttaaacg ctggatcata
    10981 aagaacctca acaatctggc ggtgttccat gtacaccacg acatctatcg tggtgtacag
    11041 cgttttcata atcacgtcat aatccagcgt ctggccgacg ccggtttgct tgataagcag
    11101 cgcaatacgg ctgaaagtgg attttgcatc gtcggcgtgg gtggatgtga tcccgcccgg
    11161 atgcccggta ttcagcgagt ttatgtaatc ccatgctgca tcatccctaa gctctgtcat
    11221 catgatacgg tcgggagaaa gacgcataca cgctttcagg ctgaccgccg gggccagacg
    11281 gccatcctga tcgccgtaca gcatataaac catttcgtga tgcagatcag acccaatttc
    11341 gtgaacgtcc tcggaaacta caatgcgctc ggtataaggc acttcccgaa gcagggagcg
    11401 ggtaaacgtt gatttacccg aaccggtaga ccctgataca acgatgttca gcttgttgcg
    11461 taccgcaatt ttaaaaaacg aaacgaggtc gtctttatcg agcaactcca gcaattcttg
    11521 ctcgaatggc tgaagggcta cttcaccctg aacctttcgt ttccagccag tgaaacggcc
    11581 ctcatcgcgg agttgttcaa gagacttatc aacgggcaga tgcttacgaa acgcgatggc
    11641 tactgttccc tccagtacgg cagggggtaa gcaaataatt ccccttgagc cgtccggcag
    11701 aagcacgtta ttaacggact ctttcggtag tccgttataa ccacaaagcg tgtcggttaa
    11761 gcgtgatata tattcagccg taattttctc atcgtcgtgg aaaatacgac ctttcgacgt
    11821 ttcacagaca acctgctgat acttgttaat tctcagctcc cacacatcgg gatcactcag
    11881 gtagcgctga agtggttcga gcgtcagcca taccccctgc tcacggcggg ggcgttggcg
    11941 aatatcttga atattactgg ttaactcagt cattcatttc taacccatat acagtgctga
    12001 aatccagatc gcgggctacg tagatggata cggcatcgcc ctgcgcagcg tagagcgttg
    12061 gcgggatatt aatcttcgcc cgtaatgctt cagtagcaag ctggtcggta ctgttttccg
    12121 ttgtgttaaa cgtcacatcg gagttgttgt tgttaatcga cgcgataccg gctttcatgc
    12181 catcagtcag cacagagaag aaaatggcat cgcccattcg ttcccaaaag tgagagttga
    12241 cctgaccagg tacgcccgca ctacctaaag cgttagtgcc gctgctgtcg aggttaacaa
    12301 tggtctgatc cgggttacgc aagcgtgacc agagaacgaa cacacgattc tggccgttct
    12361 ggataccgct attctgctcg ccagtgacca cagccccttt atcaatcagt tttacggtgc
    12421 catcagcaga atacacatca cggctaacag tacatttcac ctggcccgga accgtggtat
    12481 ccagttccgt atttgtaccg caaggaatca tagttccctg cgcaatggtc agatttggat
    12541 gcggcattac agatgcctgg gcgacagcca tacgcgccgg tttcattcgg ctcgccagtg
    12601 cctggctgtt tgagctggtt tctgtattat cctgacctga ccggcgttcc tgttctttcg
    12661 cagtcgtagc ctgtttctca ggatcgacac cgttgaagga cacacctaac cgggcgcgca
    12721 taattttttc ttccggtgat aactcctttt tctggttatt caatgtttga cgcgcaacct
    12781 gctgctgcgg ctcctgcgtt gtctgcaacg gaggaacaac gctatttttc ggcgtgttgt
    12841 cgatggtcgg cggcacatca tcaaaagact ggcgcggtaa ggagctggtc ataacctgct
    12901 ctttatcctt tttgggatcg tcggccagct tcttaacgtg catctggtta tagatgaacc
    12961 accccaccat tgccgaacct atcaacacca tcagcccgac aaaggcccgc gcaccggcaa
    13021 tacgtttttt gggggaacca ctgaagccct gacgctcatc ctcaatgccg gtatcttctt
    13081 catcgaggta atctaaattt tcctctctgt cttttctcat gatttatccc cctcaccctt
    13141 tttcacgcgc ttaacgtctg gtgacgtagt gccggtactg atcgccccaa gatttgggtt
    13201 gtaattcata ttcaggacac ccacgacttt atttccgtaa cgaatacgcc attctttcgc
    13261 taccgtttca gccacaacaa tgttgttata ttccccggct ggatgctggt taacggtatg
    13321 ctctttacca tcatcaccaa tatagaaaac aacgggtaaa tctgcgtttg cagggaactt
    13381 gaagtaagtg aaacggaaat tatcccaaac gtttaccggg gccacagtcc gatattcatc
    13441 ttcatctgac attttataaa gcaggttgta aggcccgttc tgaaggtctt tcaacgcctt
    13501 tttcacgcgg ttactttcca gcgttttatt agcctttttc atgtcctcaa acggatagag
    13561 gtaagtaagc tggagcgtgg catttttcat gctccacggc gtcttgataa agttggcttt
    13621 aacgttaccc tgcgcgtctt tcgtggtgta gtcacctaca tagtgcagca caatgttata
    13681 agtgcgtttg tttgtgacca gaacaaggtt agtatcgctg ggaacttccc ctttcggctt
    13741 gataaacatg ttgttttcaa catgggtaaa cgcataacta ttgctgtcac caaaagcgtg
    13801 tgtcacatag ctttcatcag gcgcaaccac gatatgagtg gcaacaccgg caacggaatc
    13861 aatacgcacc acgtcaaccg ggttatacac cacggattta atacggtagt cgtaggggct
    13921 accttttccc acttccagcg ccagcgcctg accagagagg ccgaggctga ccagaattaa
    13981 accggcgatt aattgttttt tcatgatcag cctcccactg cgccaacgtt ctcagcgttc
    14041 ttacggtaac tcgttacacg gaagccaagc gggttgatat agcgctgctg cgcggtcatt
    14101 ggtaacgctt tgtactcata cgcaatcgtg gcaatccagt agcgcggcgg ctcagggttc
    14161 ggacgctggc gaatgcgctg ctgcgtggta aagcgaacgg tggcaacacc gtgttcgcgg
    14221 tcggtgatca ccgagttgat atgaacggtc gttctttcag agtcacccaa ccgcttatca
    14281 atgcggttcg ggcctttgaa catggagaga tattcatcgg ctacatcacc ggaagccatc
    14341 aggctcatgg cgtcataatc aacctgaata ctgttgtagt cgtaggactc acggtgaata
    14401 acaaattgtg aaatccaata ctggtctatc acgtcgccat aagtcgcttc atcgcgggta
    14461 attttcacct gcgatacttc gcctgtatct ttattaatcg tggtgaggta tgccggtaac
    14521 ggctgcgcaa aacggataat gacgccgacc gcagtaatca tgctcacaac ggcaaagacg
    14581 aaaaaggccg tggcaatttt ccaggcgcga gagcgggaat taaggatctc attaaccata
    14641 tcgcgctcaa gcccttgagt ttcctcatgg tacttattca gatcttcccg cgatatcgct
    14701 tgatgtttgt ttttcttcag cattgttact ctccgttgtt agcggcatct gcacgataca
    14761 gctcggcggg atacgtctta ttaacatcaa ccagcttttt catgttgggt tctggcggcg
    14821 gcgtcgggct actggaacag gcggccaaca gcagcccgat aagtgccatt gccgtgtatt
    14881 tgaagaaatg caccatcttt gtcactccct ttgagtcaat cacaaaaaaa taataagtca
    14941 tcaaaattac aatttcaatg acttattaaa aattaatttc tactccactt ttagcgccgt
    15001 gaaccctttg cgaaaccctg catttgggaa cccgcagcgg tggccgctcc cgcgccgggg
    15061 ccaccggcag ccgtcgcagc agcggtttta gcaccattcc ctgtaccagc tccgccttta
    15121 gcaccaccgc cctgattatt gacagcgttc tggccgcccc ggctgccacc accaccagga
    15181 ctagggatta actcctgaat gcccgcagaa ataccatctc cccaacgaga ggcaatttct
    15241 ggtacgcgca tcaggatcag gtaagagaca atcattatca gcagacacgc gaacacaggc
    15301 cctaacaggc tactgtcagc cccggaagcg gtgacggcat cgagcgcttt ttgatagaac
    15361 ttaatcatca ggccaaacag catcgacagc agaactgtta ccagcccata gttaaccatc
    15421 gagccaagcc atttattgaa catgccatac agcggcttga acaacaggca gaagataaag
    15481 ataggcccaa agcacacagt gattgccagc agtaatttcg ccatcagtac cagcccggcc
    15541 ccgataccac agatcaacac cgtggaaata atgaccgcgc aagccaggaa taatgacgcc
    15601 agcccggaac cgctataaat atcggcgtta tcaaacgcag tacgcgcaac ctgcatcccg
    15661 tcatggatgg ccttgtcgat gttgttaccc attgcatctt cagtgccacc ggacgaaccg
    15721 ttaataacca gtaccgagga aaactcatcc gggatcttca tggccgcatc agccagttgg
    15781 gtttgataca gcccgcccgc gctggcaaag ctgattatca tcgaccacac aatgaatttt
    15841 tttatcaacg atgagagcgg ctcaccgtgt ggacgggcta atgtaaacag cccgtccagg
    15901 gtgagtttgc aaatcaacgc taacccaatt accggtgaaa tggtggatat aacaattcca
    15961 agattagagg ccacaaattc ctttgtgacc gtatccatgt aattgaaaat atccgttgta
    16021 aatgaaaagg ccatgctttc cccctaccct aatcagggcg tgacttttgg cattgagagg
    16081 ccatcatcac ttttgccaaa cactttcaaa tctttctctg cttccagcgc gttctgacaa
    16141 tctggcttca ctttgagcgc cgcatcatca cggcattttt ccaccatcgc tttacgctcc
    16201 tgatcgtgtt ccttgtacca ggaaacagga tgttcagaat cacaaccggc cagcaggaaa
    16261 agagctaaag gtaaaatcag ttttttcatg gtttattccg ttacgttagg catggaaaga
    16321 tcttcaccgt cagcgccgag gacaaagcgc ttctgggcgt attgtttttg ttcctgcaaa
    16381 atcttgtctt gcgaggtttg cagcatcgcc atcagttgca gcttcgtttg ctccccctga
    16441 atagcacctt gcgcggtctg gatacgcgcc tgaaggtcag cgatttgttt catgtccgtg
    16501 gttgagtcaa tctgattggt cagctcctga atgttattca gctccgccat ttcattgttg
    16561 taagcgttct gcgccatcac acggtcatac gcccctttct ctgccaattt ctgcttaatg
    16621 aaactcatcg cttcggaacg gttcataccg tcaatctgcg actgaaattc cttcagcatg
    16681 gattgagcag atgaagtgat gcctgaactg ctgttcatgg cgtcgctgta tacctgcgtc
    16741 cagtcagacg gtaaattgcc tttcagcgta ctaatatcgc cattcagcaa attaccaata
    16801 ccagaactac cggttaagga agccagcgtt tgctcctgct tcagcaattg agatttgagc
    16861 tgttcaattt gctgcgtcat taatgtgacc tgctcaagcg cctgggccag atttgcagga
    16921 tcgttaacta ccagttgcgc attaactgca accggcgaaa tagccagagc taaaacaagg
    16981 cttacaagtg tctttttcat gtcgttacct cacgctgcga gtacagattt ccagtagggt
    17041 tcgagccatt tatcagggtt atcatcccca atttgctcaa taattttcgc cagtgtttcg
    17101 gcgttttggg tttcccctga caggatgcta aggatcttat ccagcttcct gaagttctcc
    17161 ggcgtcttaa cgcgcggggc caggttgaat tgcgccatcg cgctttgact gccttgtttc
    17221 accaggaact ggcgggagtt ctcaggaata gacagcagcg cgtcaaactc tgccggtgtc
    17281 aatttgaggc gagtaacgta gtcctcataa tccgcatccg ggttttccag aagaattttc
    17341 gttacgcact gctgcatgat ggttttaccg atggagctat ccagcgcatc gttcggttct
    17401 tgcgtggaga atacgtaaac cgcatctttc ttacggtctg ttttaaggcc acgcttgact
    17461 tccacactca taattggatc gtcaaggtac tggtgaaact catcgaatac ctgaatcaca
    17521 cggcgacggc catcaataga ctgacgtaca cggaaattga gatacatcag gagcggagta
    17581 cgtgttgcag gagggatctc attatctgca acaatgaaat ctgtcaggtc aaagccgtag
    17641 atatcgtatt caccaagatt cagtgaatcc gagtcgttat caaacaacca accgttttca
    17701 tggccgcgag tccagggaac aagcaaggat gccagtgttt gtttactgcc tgctgtttga
    17761 tatggattcg gcatctgctg aattaacata tccacggtgc gtaggtctgt cggaatgagg
    17821 gagttctcat ccatcaaagc atccacggcg cggttaagat cattaacctg atcagcatcg
    17881 agtacgctac ctttggtaat ttcagcgcac aggcgcatca ggcgcttaca aaatgcaatg
    17941 ttaactttag tgccaggcat ctgtagaggt gcccacccgg aagcaacacc ctctttcaga
    18001 accgtatagt gaccgtgtaa cgctttaatc atcggcatca tgccctgatc gcggtcaaag
    18061 gcaaaaatgc gcgggttata cttcatagct tgcgtcagca ggaagttaag cagtgtggtt
    18121 ttaccagccc ccgaacggcc aagcattaac gtatgcgcca gcggtcgctt accgaaagac
    18181 aattcatctt ctggcgttac atgtaagttc atatacagcg gcgtatttgc cacggttttg
    18241 aacagcgtca gcgctggccc ccacgggtta ttatttgctt tcccggacat aaaattatgg
    18301 aagggagaga agcaaagaaa attccagcta ttcagcgggc aaggtcgtgg cgacaggtgt
    18361 tgattagccg gaagttttgc ataatatgcc gcttctgaag ctaaccctac ctggctggca
    18421 atcagcccgc agttgtttag catatttttg gctacaccgg cgttagaccg agcctctttg
    18481 agagacttgc caaaggtatg taccgtcagg tgatgccagc ccatgataaa tgtacgtgaa
    18541 acaacgccat caacggcgtc agtcatctgg tttatctgcg tataggatgg atcgcctgtt
    18601 tccagcagcg ctttttgctg gttagtgagg taagttcttg ccgcttgctg ggacatacag
    18661 caatacgttt gcgttaacac aaactcaaac ggtgcttcca tcaggatatt gatctggccc
    18721 ggctcagtat cggaatcgta atcccggatt tcaacagcag acgtatagcg gcgttcgtca
    18781 gtaccacgaa tctcgatgcc atccccccat aatgaggaag ttggacgggt agtaaccaaa
    18841 tattcacgaa tacggccacg acaaaccggc accggcgccc attcaccatt aacaaggtaa
    18901 tagagccact ccagcgcttt agaaaaggtg tgttgcgtac cactgaaggc ttctttatcc
    18961 gcctgaacgt cctgatattc cacatcagcc agcaaatctt cacgcagatc gataatatcc
    19021 tcatcatctt ctgcatcgtc ttttttctgc tcaggaatga tattcccccg tttatcacgg
    19081 aagtagtaac ctaaacggtc aatgccgtaa ggacgcatgg agttcatgac ctgttcgcaa
    19141 atatcttcca gcgcactaag agcgtctacc tgcatttcac gcagctcgtt gggcgatggc
    19201 ttgtcaaact ttgccagcat cttttgagca gaatccccca cagggttata aacaaccgtc
    19261 agatacaggt catttaccat catgggagta tcatcaaact ggtcacgata atattcattc
    19321 accatgcgcg ggaatgtcat attgtaatgc gtgtcaggat aattattaat ttcgcggtgg
    19381 tgtaagtgag tccataattt cacatgctca ctaccaatcc cttttaaaag ctggttcaaa
    19441 tcagcgtgcc acttaatcag ctcggcatca gaggcacagt catgggttcg cccacggatt
    19501 ttaaatatag aaaggtattc cccatttacc gtactgataa catggggcgt gacatgatag
    19561 gagtaaggaa tatatttcaa agaggaaggt tcttttttgt aatctttcac cccccctttt
    19621 tgcatttccg ctacggccat tattttttat ctccataatc agtaggtgag taactagagc
    19681 cgccccacag tttagtaaac ggggagttaa tcatatttag ccctttcgtc atgatagcca
    19741 gccatataat acgaaacata cggtcatcat gtttgctgat acaaaactca ataaaccaca
    19801 gcaagccaaa aagaacgatg gcccaaaggt ggatcgtcat aaataacgtc gcacaaaata
    19861 tgaaggtggc aataattact gttcgcggaa caccggcaaa tgtcggcagt cgcgtcgcgc
    19921 ctttaaataa cggatattta ccggataaat tcatcgtttc ctcccgtcag atacgggccg
    19981 ggggaatacc cccccggcga accttcttaa ctcagaccga aaaggccaac aaggaaagac
    20041 gcggaaccga caacaatcag gccgacaaca atacgaaccg cccagctcgc cgggagcata
    20101 tgagcgatcc atgcgatagc actcacgatg ataagaacgg tggccgcaat cggaatccac
    20161 gtcattaacc atgagttaat ggaactcatg gatgattcac cggtatctgc accggcggcc
    20221 agcgccagct caggaacgca aagggcgacc atcatgaaca ttgccaccgg gaaaaaacgt
    20281 ttaatcgctg tattcatctt tgtctaacac tccatcatca ggaaaaataa aatcaggctc
    20341 atccaggaaa agccccactt ctcttgcatt aaaatcgtct ctcagcatgt cggccagtat
    20401 ccgcagatcg gcccacgttc taaccccctc tccagactga actcgcaggg agcaagtgat
    20461 tacgccccct tcactatttt tcacatcaaa aagcggtatc catttctttt tatccatccg
    20521 ttgaatagca atccgcacaa ctttgttttg attgaatact tcttctaact gcttcaacaa
    20581 gatgagataa acgcgcatct aaactgactc ctgttactcc ctacttctgc cggaaagcgt
    20641 caccatcaga tgcaccaaaa gcgtctttat ccgagccacc aaaggcatca gtcataccgg
    20701 cgtcttttgg ttgttcttca ccatcagcag catctaccgg cacagcatct atagctgtat
    20761 caacactttc cacatcagtg gagccatcat cggctttcag agcagggatt acgggttttg
    20821 attgcccaat ttgagcaacc acctttgata cataaccgtt tgtaaatccg gcggttagtg
    20881 accccgtatt ataacaagat aaagcgtgtc tcaaagctga ctgccccggc gcatactctt
    20941 ttgttgcgag ctggtagcag taattaagaa cgtattgagc agcttcgaga tttttacaac
    21001 cgttaaacaa atctgcggca gaaacgttca attttgggaa attcgcagag ttgatttgcc
    21061 ctaaacctac gtcaaagtta taaccatgag ccgttagcca ttttgtcgtt ttaacagctt
    21121 catccaggga gcgcggctgt ctggctaacg gtgattttgt tcctttagga acgttgacat
    21181 ttatcgcgta tgggttgttg cgcgattcat ggctaaccag gtacccaata gttaaaggat
    21241 gcacttctgg cgcacaacgt tttgccagtg ccataaccgg cgctgacagt tccgcatttg
    21301 cgggtgtggc atccaaaagg ccagcaatca acagtgggaa aagggcaaca acctgcttca
    21361 tgtctttttt ccttgaaatt gcaatttcaa tgattaacta gtatagtaaa ggtaaattcg
    21421 aacatgtcaa gacaagatga aaagaagcac aaaacagagc aggagcgcga aacatcagtg
    21481 cctaaaagaa aaatcatatt cgtacccttg cagtcagaaa aaagccccaa aggggaacct
    21541 cgctaccgag atccagccaa cccatttaac acatgggttg gaaggggaaa gcgccctgac
    21601 tggctaaaaa agtatcttga cgaaggccgc gaactttcgg agtttgagat cgcagaataa
    21661 ggagttgacg gatgagtaaa attattgatt ttcctaccgg aaaaaagagg gagaaaaggg
    21721 ccaaagcgat ccgagcgcgt cgcaataaag aagcgcagca gcggagcgaa ataaccccct
    21781 ccaaattttg gtgggttaag aaaataaagt tactcaccgt gattaaacaa tcggcgcgtt
    21841 ttctcttatt acatttaggg ttattagttg ccgacatcct tatctgtctc cttcttattc
    21901 taggaaaact cctaaaaatc tttacgatga ttggtatcat cgcggcactt ctgtttctgg
    21961 tcgtggaata taggaatgat tggcattata cgcaatctgc actccatgcc gcagcaatat
    22021 ttgttagcct gattgccctg cgcatcgggc atgacaaact actgaatggc ctaataaggc
    22081 ttaaatccca tctatccaga aaagggtgat aataatgcgg aagataataa ttgcatccgt
    22141 ggtgatactg gcatcgtctt attcagttgc cagcttcgca aaagatcctt gcaagacatt
    22201 agcttgcatg gctgcgaaat caggtggtca atttgggagt attggcgata gtgattgctc
    22261 tggtgctatc gctgacttct tcaatatcgt gaagaaaaac aagcatggct tccttcctaa
    22321 tcacacagca gatgcacgta aagaatttct tatggaatgc tcaggagcgg agcagaacac
    22381 cgccgctgtt agcagggtta tttcaatgtt tggacgtatc aggaaaggtt aaatatgaaa
    22441 actaaaagca tcatcttcac cgcagctctc ttactgaccg gttgcgccag tcagtcacaa
    22501 gttgaccagt taaccaagca ggtgaatacg cttaaaacag atttgtataa cctacagatt
    22561 caacagcgca atgatacaca ggcacttcag cgcgaagtac agaaatcgcg ccccatcggg
    22621 gtttgctatc ttgacggcca accctactca caaggagcgg tcattgctgg ccgcatttgt
    22681 gccagtaatg gcgttatcgt caatggcaaa cctacagaag tttcatggca ggtttatcac
    22741 cgccgctaac aacgcgcgtt cggggcttcg gccccgtttt ttatggtaca ggtagcatgg
    22801 atatactttc ccttttcccc tctaacgtaa tcgcattgtg ggccgtgtct tttggttttc
    22861 tggccgtcct gtattggtgg aagatcaccg ccagaaaacg cagacacaaa cgtaagcaac
    22921 aacaagcccg gcgtgtactc gcaaaaattc agaccctacc ggcgttcggc tacaagatcg
    22981 cgtatctcag gaagatagac cctttcacct ttgaggaact gttactggag ggatttgagt
    23041 cgcatggctt cagcattatc agaaacaaac gctataccgg tgatggaggc attgacggcc
    23101 aggtaataat cggaaaacat cgctatctca tccaggccaa acgctatcgc ggccatattg
    23161 ctttacaaca cgttcaggag ttcgatacgt tgcttaaacg acataactgt cgcggtttgt
    23221 tttgccatac cggaaaaacc ggcgcagctt caaaagctgt tagcttcgcc agcgatagga
    23281 tggaaattat cagcggccag cgcctgattg atttactcac gcccggcagt tccttcacca
    23341 tcgcaaccgc accgcagaca atgatgaggc gtaccgcagc aacgcgagga acgaacacca
    23401 ttgtcgagga agcggataaa aagacaaccg atagcatgag agttaattaa atgaagtcag
    23461 taactataga agcaaaaact tttgctgaaa tgttgggggt aacagaaggt gagttaattt
    23521 tcgctattaa gacaactggc acatttaaaa acaaagccat cccacaacct catgaaccac
    23581 ataaatcaaa taacagattt ttatattctg acgtaatgaa atttatcgaa tcaataaaag
    23641 ataaagaaaa cctacaaaaa aaatatctga tgcgtttccg tcgatgcagc tcgttggaca
    23701 ctcttgaaaa agtatttgat agcttacgcg ataagctatc aggtaaagaa ctggatgcaa
    23761 tgatgagcgc ctcagaccat cggagagccg aaatcactca caatacttta tgggataaag
    23821 tcccggcctc cgcatggaga aatgtaaaat aaaaaaagcc cgctaacggg cttttttttc
    23881 tcactacgac catttttctt caatgctccc attacagcga acaaaaaacc ggaacaaaat
    23941 cactgctaca catttcgtta cgctcgtgca cgttgtataa aacaagacct gcactgataa
    24001 ttattccaac aaacccgccc aaaatcatca ttggaatttt gttgtcttta tttttagtaa
    24061 ttgaaccaaa gtaaaaaacc gtacctatcg taattgttaa agaaataagc aacatcacaa
    24121 atttaaaaaa acccagggtc ggcattccaa taataacaac agcaaaaata atgccgaaca
    24181 cccattttac aattgccaca tcattgattt cttgtttatc actcatgttt ataacctttg
    24241 tttaatatta cctatccaat caagactttt aatttagacc tgacctcagc caacacagca
    24301 gcagacactt ttcctttctt aactgccccc cgttcacgcc aatcaagact tttcacctgg
    24361 tcagcgagta cagcgctccc ctctccattc cgtacctcga atggataacc ttttattttt
    24421 gttgtcatag ggcagcacaa caacagccct attcttccgt tatataccgc aggacttaac
    24481 actaaagctg gtctatggcc cgcttgttca tgcccggctt gcggatcaaa atccatccat
    24541 acaatatcac cggcatcagg aatataatca cgcttcatta tttagtctct tgctgatata
    24601 cccaacccat ataaatgcaa tgataatcac cccgcaaaaa atgaacatta ttgcaaccgg
    24661 agttgtgtca agcagagata caacctcaac accaccaata gaaaatgagt tatctttaaa
    24721 taatttacta aaccctaacc agatggaata caacccaaca ccaacccaaa taagagcacc
    24781 taaaaactct agatagctat aaactttttt caaaaatttc agcataacgc ctcctaaaga
    24841 acctttttga atttctgctt ccactcatcg taactcatat tacttttgta atgttcccgc
    24901 cacttctccc aatgcttgcg gcttacatct tctagacctg tttctgtaag attttcactc
    24961 aataaccttt cgaaatgagc cgcttttata cctgaatatt tttggtgaaa ttctttagtt
    25021 gccttataca ttatcacctt gctgattaag gtatgattaa gtctcccaag aaaatatgca
    25081 gccgcatacg attgagccat gataataacg aaaagataac caaccgagag aatataatca
    25141 cctatactgt aagttccgtt atcaaggtat aagctcgaat catgataagt aactggtagt
    25201 tttaacttag gttgcatcca gttaatccat tcagaaaaat aatatggaac tggattatta
    25261 actaagccta acactcccat tacagcgtag cacaccaccc cgatagctaa ggcagcagta
    25321 aaaatcttac agctaaggct gacccatcta ataaaggatc tatcctcttt tttcattaca
    25381 acaactcctt cccaacagga gcgccgaaag aaatttcctc atgaatattt tcgttagtaa
    25441 caccggccat cagagcatcc agtgaatact cctttgtttt aacgggcacg atagtaattg
    25501 cgccgtcctc tactgacagc tccactacat catcaacgtt taacgaagcg gctttcacaa
    25561 tcgcagaagg aaggcgaaca gacggactat taccccattt tttaattatt acttgagtca
    25621 tgacatacct ctcaataaac aaagaaaact aattagcgac tcttcaggat gtaccaggct
    25681 tctttcgctg ctgaaagcgc ccaaacccac gccagagtcg atgcgataca taatgcggtc
    25741 atattcccaa agtgtcccgg cgtgtattca tggccgtgta aaacaagccc aaccaaagaa
    25801 gccacactca tcactatgaa aacaatccca aacatgatgt gaaacataag gccaaacact
    25861 cattacctct cgtatcatca ttgttgatac atccagtgta gagccacccc tttaacgtgt
    25921 caacattgtt gatacagaaa gtgtctcaca aacgatgatt tttgttacac agcccccacc
    25981 ccatccaaaa atatcaaaat ggatgttgtc agtgtaacaa aactcgttac aatactaagt
    26041 gtaacaaaaa cggtgtaaca aaagcagggc atatgaaaat aggctacgcc agaaaatcaa
    26101 ccaaagagca agacacatcc cttgagtatc agatcgaggc tttacaaaaa gctggctgcg
    26161 aaaaatggta tgcagagcag gtatcgaggg gcggtaataa gcgcctgaaa acaggtacac
    26221 cagagttgga aaactgtctg aaagcgcttc gcgccggtga cacactggta gtatgggcgc
    26281 tagaccgatt aggtggcact ctcttgcagc tcttgcagct catgaatgag ctacgcagca
    26341 aagggattca ctttgagagc ctcaaagagc gcatagacac acaaagccca atgggtgaaa
    26401 tgtactattc cctcatcgct attttttcca atttcgaggt agccagaaac cacgaaagga
    26461 caatggccgg gcttgcggcc gcaaagaaga aaggacgcat tggaggcaga aaaccaaagc
    26521 tatctccaca ggacattaaa gaaattaacg cgcttgttaa atcgccagaa attacggtaa
    26581 aagagatcgc ggcacgtttt aaggtttcac gtccaacgat ttacagacat attacccccg
    26641 acagcaatac tgattaaccg gcggcaaacg gtagcgaagg agcgaaaaag tgacagacaa
    26701 accattacca gcgaagcaaa taaaaacggt aaacaccggc atcgcaatta aagagaatcc
    26761 cccaaaaggg gatgatatgg cgtttactca ctcgatattg tgtcaggttg gcctaccccg
    26821 ttctaaggtg gatggccgcg agtttatgag gaaatcaggc gatgcctggc tggtcgtcca
    26881 agctggctgg cttgatgaag ggagcgggcc tgtagaacaa ccgatcccct atggttcgat
    26941 gcctcgttta gcgctcgcat gggtatcctc ttatgctctc cgcaaaaaga cccgcgaaat
    27001 accgatcggt aagagtgcaa acgaatttct gcaattaatg ggcttatcag gtggcggcag
    27061 acaatacaaa acgttgcgcg aacaaatgca cgcgctggcc gcttgccggt tgcagctcgg
    27121 atttaaagga cgttctttca acggtcagcc cgtagaacaa ttcgatgcct ggcagaaaga
    27181 cgaccaaagc ggccagttaa gtttatggcc gggcgtaatg accctatcag aagggtattt
    27241 caatgggcta attgatagcg ccgttcctct cgataaccgc gctctgtacg ggctaaaagg
    27301 ctcggcattg tcgttagatg tttatacgtg gctggcacat cgtttacacc gcatcgaggg
    27361 ccgcccgatt aaacttcact ggatgaattt acgggaacag ttcgcccaag agtacatggg
    27421 taaagaccct gacaaggatt tcaaaaagaa atttcttcca gctctgcgcg acgttctgac
    27481 cgtataccca caggcgaagg tagaaaaagt taccggggga atattacttt acccttcccc
    27541 gccccctatc ccattcaagg aagcaaaaaa ataggcccat gcgggccttt tttatttcgg
    27601 gttaatgcca caccactgct ttgagtcaag ttatggataa ggtgaataag cctgtaaaaa
    27661 agctgttgaa acataaagtt
//
LOCUS       DAFGPF010000061        27473 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFGPF010000061 DAFGPF010000000
VERSION     DAFGPF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27473
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.061"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            121..1464
                     /locus_tag="LSX49_002915"
     CDS             121..1464
                     /locus_tag="LSX49_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL7169303.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDAASLARNPFRVFTSLLRLELIENELLRQKAAEILRQRDIFTPRCR
                     QLLQEYEQRGGFNETQAQEFVQEALETFRWHQSATVDEKTYRALHKEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLGWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVVAQPITYEDFLPVS
                     AAGIFQSNLGNETQACNHGDASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            1689..3344
                     /gene="opgD"
                     /locus_tag="LSX49_002916"
                     /gene_synonym="mdoD"
     CDS             1689..3344
                     /gene="opgD"
                     /locus_tag="LSX49_002916"
                     /gene_synonym="mdoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein OpgD"
                     /protein_id="HBL7169304.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKNQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEK
                     WARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            3484..3708
                     /locus_tag="LSX49_002917"
     CDS             3484..3708
                     /locus_tag="LSX49_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HBL7169305.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQVSVKEV"
     gene            3771..4310
                     /gene="rimL"
                     /locus_tag="LSX49_002918"
     CDS             3771..4310
                     /gene="rimL"
                     /locus_tag="LSX49_002918"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HBL7169306.1"
                     /translation="MTETIKVSESLELHAVAESHVTLLYQLICKNKTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     PHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDSQ"
     gene            complement(4302..5282)
                     /locus_tag="LSX49_002919"
     CDS             complement(4302..5282)
                     /locus_tag="LSX49_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LbetaH domain-containing protein"
                     /protein_id="HBL7169307.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKSVLLRQIIAMSDFNDVIAGSAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGTVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAYISDSVTISDSLVCGQCRIFGHALIDQHSMIVAAQGLTPDHQLLLQIYDRAKV
                     SASRIVHQAQIYGDAVVRYAFIEHRAEVFDFASIEGNEENNVWLCDCAKVYGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLIGGNAVVRGGPILLDEHVVIQGESR
                     ITGAVIIENHVELTDHAVVEAFDGDTIHVRGPKVINGEERITRTLLAGLL"
     gene            5406..6398
                     /gene="tehA"
                     /locus_tag="LSX49_002920"
     CDS             5406..6398
                     /gene="tehA"
                     /locus_tag="LSX49_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HBL7169308.1"
                     /translation="MQNDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGL
                     VILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFR
                     PLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG
                     YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSV
                     NGGEGDTLAKMLFGYGLLQLLFMLCLMPWYLSQPFNASFWSFSFGVSALATTGLHLGS
                     GSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLVRTERAVLMKAEDKE"
     gene            6395..6988
                     /gene="tehB"
                     /locus_tag="LSX49_002921"
     CDS             6395..6988
                     /gene="tehB"
                     /locus_tag="LSX49_002921"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HBL7169309.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDGQYDFILST
                     VVLMFLEAKTIPGLIANMQRCAKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWEMVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            7291..7959
                     /locus_tag="LSX49_002922"
     CDS             7291..7959
                     /locus_tag="LSX49_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HBL7169310.1"
                     /translation="MRTTSFAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     TSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQGEGKDLNNESTPMAFENIKQVIDDMATDATMFD
                     VNKK"
     gene            complement(7994..9205)
                     /gene="ydcO"
                     /locus_tag="LSX49_002923"
     CDS             complement(7994..9205)
                     /gene="ydcO"
                     /locus_tag="LSX49_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BenE family transporter YdcO"
                     /protein_id="HBL7169311.1"
                     /translation="MLRYLYVITHEVTMRLFSIPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQELT
                     LNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLAWLAAKAVAPRYAVIAAMIIGIVIVTAQGDVVTTDIVFKPVLPTYITPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALFFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLIAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLFGIGSAFWGLIAGGVCY
                     VVLNLIANRNR"
     gene            9258..9794
                     /gene="sutR"
                     /locus_tag="LSX49_002924"
     CDS             9258..9794
                     /gene="sutR"
                     /locus_tag="LSX49_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SutR"
                     /protein_id="HBL7169312.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQSATPSVYDPQRQAMVITSLFPYDPQLCFEHF
                     SIQMAPGAISESMPHEKGVIEHVVVIDGQLDLCVDGEWQSLNCGEGVRFAADVTHVYR
                     NGGEQTVHFHSLIHYPRS"
     gene            9867..11828
                     /gene="rlhA"
                     /locus_tag="LSX49_002925"
     CDS             9867..11828
                     /gene="rlhA"
                     /locus_tag="LSX49_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HBL7169313.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLEQIRAIHQATNATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVLKVAKDHIDV
                     AVTEPLANGDGLNVMIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWHQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSVTHTLDGQFDEANNA
                     EKAMNNLKDGLTKLGQTIYYARNVQINLPGALFVPNSLLNQFRREAADMLDAARLASY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDDLLKTLPKRKG"
     gene            complement(11920..12150)
                     /locus_tag="LSX49_002926"
     CDS             complement(11920..12150)
                     /locus_tag="LSX49_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2554 family protein"
                     /protein_id="HBL7169314.1"
                     /translation="MFSKALSVVLLTCALFSGQLMAGHKGHEFMWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            12329..12565
                     /gene="hicB"
                     /locus_tag="LSX49_002927"
                     /pseudo
     CDS             12329..12565
                     /gene="hicB"
                     /locus_tag="LSX49_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
     gene            12644..14050
                     /locus_tag="LSX49_002928"
     CDS             12644..14050
                     /locus_tag="LSX49_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL7169315.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESQGYIIARPQSGYYVAPQAIKMPKATVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDIKEGIDLQALELALQEYPVKACWLMTNSQNPLGFTLTPQKKVRLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHNDSGYFLWLELPEPLDAGELSLVALTHHISIAPGNMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGKLIQERL"
     gene            14295..15440
                     /locus_tag="LSX49_002929"
     CDS             14295..15440
                     /locus_tag="LSX49_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL7169316.1"
                     /translation="MSKTFARSSLCALSMTIMTAHAAEPPTNLENPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMAKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKTLDPRVVKGDWFNVSGKVYGTPYQWGPNLLMYNTKTFPTPP
                     DSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRDQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPQGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPVAEGGKFVPYSRWTQDYIAIMGGR"
     gene            15458..16471
                     /locus_tag="LSX49_002930"
     CDS             15458..16471
                     /locus_tag="LSX49_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7169317.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGTPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVNKKQRHAMAQEALEKVALGFVQQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDPLMAEKLCGMTGSFALRPEHIRLNTHGEMQANGT
                     IQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVALV
                     EER"
     gene            16472..17413
                     /locus_tag="LSX49_002931"
     CDS             16472..17413
                     /locus_tag="LSX49_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7169318.1"
                     /translation="MAMNVLQSPSRPGLGKVSGFFWRNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIIVRTLTMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIVLIALYLAFVKRLGAFDAL"
     gene            17403..18197
                     /locus_tag="LSX49_002932"
     CDS             17403..18197
                     /locus_tag="LSX49_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7169319.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            18219..19643
                     /gene="patD"
                     /locus_tag="LSX49_002933"
     CDS             18219..19643
                     /gene="patD"
                     /locus_tag="LSX49_002933"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HBL7169320.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVNAA
                     VRAADAAFAEWGQTTPKARAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTAPSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGSPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDSE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
     gene            complement(19740..19835)
                     /gene="yncL"
                     /locus_tag="LSX49_002934"
     CDS             complement(19740..19835)
                     /gene="yncL"
                     /locus_tag="LSX49_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HBL7169321.1"
                     /translation="MNVSSRTVVLINVFAAVGLFTLISMRFGWFI"
     gene            20031..20204
                     /gene="ortT"
                     /locus_tag="LSX49_002935"
     CDS             20031..20204
                     /gene="ortT"
                     /locus_tag="LSX49_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orphan toxin OrtT"
                     /protein_id="HBL7169322.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRLLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            20290..20523
                     /locus_tag="LSX49_002936"
     CDS             20290..20523
                     /locus_tag="LSX49_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcY family protein"
                     /protein_id="HBL7169323.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTL
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(20524..20973)
                     /locus_tag="LSX49_002937"
     CDS             complement(20524..20973)
                     /locus_tag="LSX49_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBL7169324.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLVLDIFRSHGVPLRALIGPICGAILLVVGAWLVARRSF"
     gene            complement(20970..21488)
                     /gene="mddA"
                     /locus_tag="LSX49_002938"
     CDS             complement(20970..21488)
                     /gene="mddA"
                     /locus_tag="LSX49_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HBL7169325.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTIAGYPVLVSEEDGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVTAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            21737..21892
                     /locus_tag="LSX49_002939"
                     /pseudo
     CDS             21737..21892
                     /locus_tag="LSX49_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310081.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(21969..24071)
                     /locus_tag="LSX49_002940"
     CDS             complement(21969..24071)
                     /locus_tag="LSX49_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBL7169326.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTP
                     AAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVATTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDDASKLSLIFNSVDIKADDPGGLTEAEWKANPQQAPRAEQYDMRKTI
                     KQTQAGLRYERSLSAQDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNRGVPEYGQKGELRRDERN
                     LMWNVDPYLQTQWQLTDKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNVYLAAGRGFETPTINELSYRADGQSGMNFGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVKA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYIPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PAPGRNYGVGINIAWRFE"
     gene            24313..25374
                     /locus_tag="LSX49_002941"
     CDS             24313..25374
                     /locus_tag="LSX49_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBL7169327.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVASSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWIATSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDTTNTVYISGI
                     GKESVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNADGELITIDTTDNKI
                     LSRKKLLDDGKEHFFINISLDTTNQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            complement(25487..26986)
                     /gene="ansP"
                     /locus_tag="LSX49_002942"
     CDS             complement(25487..26986)
                     /gene="ansP"
                     /locus_tag="LSX49_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HBL7169328.1"
                     /translation="MSKHNTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQDIVFKPETAS"
BASE COUNT         6960 a         6748 c         6999 g         6766 t
ORIGIN      
        1 gttacagcaa aatggataat attgatgttt tcgcggcgag atcacagttt gtaaattctt
       61 ccagccggag tgaatgcggt tacctacact ccagattact gaccactgga ggcagacact
      121 atggcgaaca gcatcacggc ggatgagatt cgggaacagt tttcgcaggc aatgtcagcc
      181 atgtaccagc aagaagttcc gcagtacggc acgctgctgg aactggtagc tgatgtaaat
      241 ctggcggtgc tggaaaacaa tcctcaactg cacgaaaaaa tggtaaatgc agacgaactg
      301 gcgcgactga atgttgaacg tcatggggcg attcgcgttg ggactgcaca agagcttgct
      361 actcttcggc ggatgtttgc cattatgggg atgtacccgg tgagctatta cgatctctcg
      421 caggcagggg tgccggtaca ttcgacagca tttcggccca ttgatgctgc ttctctggcg
      481 cgtaatccct tccgcgtttt tacctcatta ctccgccttg agcttatcga gaacgaatta
      541 ttacgccaga aagcggcgga gattctgcgt cagcgcgata tcttcacccc acgttgtcga
      601 caactgttac aggaatatga gcagcggggc ggttttaacg aaacacaggc acaggagttt
      661 gtgcaggaag ccctggaaac gtttcgctgg caccagtcag caacggtaga tgaaaaaacc
      721 tatcgcgcct tgcacaaaga acatcggttg attgctgatg tggtctgttt tcctggatgc
      781 catatcaacc acctgacgcc acgcacgctg gatattgacc gggtgcagtc gatgatgcct
      841 gaatgcggaa ttgaacccaa aattctgatc gaagggccgc cgcgccgcga ggtgccgatt
      901 ttactacgcc agaccagctt taaagcactg gaagagacgg tgttgtttgc ggggcagaaa
      961 cagggcacac ataccgcgcg ctttggtgaa attgagcagc gtggtgtggc attaacgccg
     1021 aaagggcgac aactgtatga tgatcttctg cggaacgctg gaaccgggca ggataatctc
     1081 actcaccaaa tgcatttaca ggaaaccttc cgcacttttc ctgacagtga gtttttaatg
     1141 cgtcagcaag ggctgggatg gttccggtac cgtctgacgc cttcgggtga ggcgcatcgt
     1201 caggcgattc atcccggaga cgatccacag cccttaatag aacgtggttg ggtagtggcg
     1261 caacccatta cctatgaaga tttcttgccc gttagcgcgg cggggatctt ccagtcaaat
     1321 ctgggtaatg aaacgcaggc atgcaatcac ggtgatgcca gtcgcgaagc atttgagcag
     1381 gcgttggggt gtccggtttt ggatgagttc cagctttatc aggaagcgga agaacgcagt
     1441 aaacgtcgct gtggtttgct ttaaattctg accatccgcc tttgcaaaaa tttgcctgat
     1501 tttacaaacg aatcaggctc atcccatcga cataaaaaaa atgccaattt atgcatattc
     1561 tctgatttca acaattggat tattaataaa tattgtctag agtgagcggt cataaataag
     1621 cactttcttg ccgctgaaaa tgaccagcgc gggaccattc acaacaccag aaggactcac
     1681 tttcaggtat ggatcgtaga cgatttatta aaggttcaat ggctatggcc gccgtgtgcg
     1741 gtaccagcgg cattgcttct cttttttctc aggcggcatt cgcggccgat tctgatattg
     1801 ccgacgggca aacccagcgt tttgacttct ccattctaca gtcaatggcg cacgacttag
     1861 cgcaaacagc atggcgtggt gcaccacgtc cgttacctga tactctggcg acaatgacgc
     1921 cgcaggctta taacagtatt caatacgacg ccgaaaaatc gctctggcat aacgttgaga
     1981 accgtcaact ggacgctcag tttttccata tgggaatggg attccgtcgc cgcgttcgta
     2041 tgttttctgt agatccagca acacatctgg cgcgtgaaat tcactttcgc ccggagttgt
     2101 tcaaatacaa cgatgcgggt gtggatacca aacaattaga agggcaaagc gatctcggtt
     2161 ttgccggttt tcgcgtgttt aaagcccccg aactggcgcg ccgtgatgta gtatcattcc
     2221 tcggcgcgag ttatttccgc gccgttgatg acacatatca atacggtttg tcggcccgcg
     2281 gcctggcgat cgacacttac accgacagca aagaagagtt ccccgacttt accgccttct
     2341 ggtttgatac ggtaaaacca ggggcaacca cctttaccgt ttatgcgttg ctcgatagcg
     2401 ccagcattac tggtgcctat aagttcacta tccattgtga gaaaaatcag gtgattatgg
     2461 atgtggaaaa tcacctgtat gcgcgcaaag acattaaaca gctgggcatt gcaccgatga
     2521 ccagtatgtt cagctgcggt actaatgaac gtcggatgtg cgacaccatt catccgcaaa
     2581 tccatgactc tgatcgtctg tccatgtggc ggggcaacgg cgagtggatt tgccgtccgc
     2641 tgaacaatcc gcaaaaattg cagttcaatg cttacaccga caacaacccg aaagggtttg
     2701 gtttattgca actggatcgt gatttctccc attatcagga cattatgggc tggtataaca
     2761 aacgcccaag tctgtgggtg gaaccgcgta acaagtgggg taagggcacc atcggcctga
     2821 tggaaatccc aactacgggg gaaacgctgg ataacattgt ttgcttctgg cagccagaaa
     2881 aagctgtaaa agcgggtgat gagtttgcat tccagtatcg tctgtactgg agtgcgcaac
     2941 cgcctgttca ttgcccatta gcgcgcgtta tggcgacgcg taccggcatg ggcggtttcc
     3001 cggaaggttg ggcgccaggt gaacactatc ccgaaaaatg ggcgcgacgt tttgccgtcg
     3061 atttcgttgg tggcgatctg aaagctgccg cgccaaaagg cattgagccg gtgattacgc
     3121 tttccagtgg ggaagcgaag caaatcgaaa ttctctatat tgaacccatt gatggttatc
     3181 gtattcagtt tgactggtat ccgacttcgg actccactga tccggtcgat atgcggatgt
     3241 atctgcgttg tcagggcgac gctatcagtg aaacatggtt atatcagtat ttcccgccag
     3301 cgccggataa acgtcagtat gttgatgacc gcgtgatgag ttaatcgttt tttcttcggc
     3361 atcttcttcg ggaggtgccg tctggttaaa cacgatcccg ctcgcatttt ttcctaagtt
     3421 aaatgagtaa tctgctggtg tgtatttcag atacaccttg tcagccacta acagggagtg
     3481 cgtatgtttc cagaataccg agatttaata tcccgtctga aaaacgaaaa tcctcgcttt
     3541 atgtccttgt tcgataaaca caataaactt gatcatgaaa ttgccagaaa ggaaggttcc
     3601 gacggtcgag ggtacaatgc ggaagtggtc cgcatgaaaa aacaaaagct acagttaaaa
     3661 gatgagatgc tcaaaatcct gcagcaggtg agcgtcaaag aggtgtaaac tttcctaagc
     3721 cgccagccag gcggcttttt taacagctgc atggattgac tggagataag atgactgaaa
     3781 cgataaaagt aagcgaatca cttgaattac atgctgttgc ggaaagtcat gtcacacttc
     3841 tttatcagtt aatctgtaaa aataaaacct ggttacagca gtcgctaaac tggccgcagt
     3901 ttgttcaaag tgaagaggac acgcgaaaaa cggtgcaggg taatgtgatg ttgcatcaac
     3961 gcggctatgc caaaatgttc atgattttca aagaagatga acttatcggc gttatctctt
     4021 ttaatcgtat tgaaccactg aataaaaccg ctgaaatcgg ctactggctg gacgaacctc
     4081 atcaggggca ggggatcatt tctcaggcgc tgcaggcatt gattcatcat tacgctcagt
     4141 ctggtgaact tagacgcttc gtgatcaaat gtcgggtgga caatccgcaa agcaaccagg
     4201 tagcgttgcg caatggtttt atccttgaag gttgcctgaa acaggctgag tttctgaatg
     4261 atgcctatga tgatgtgaac ttatacgcgc gtattatcga ttcacaataa ccctgccagc
     4321 agcgttcgcg taatgcgctc ctcgccgtta atgacttttg gaccacggac atgaatcgtg
     4381 tcgccatcaa aggcttcaac gacggcgtgg tcagttaact ccacatggtt ttcaattatc
     4441 accgcacctg taatacggct ctcaccttgt attacaacgt gctcgtcgag cagaatcggt
     4501 ccgccacgta ccacggcatt tccgccaatc aagacatgat gttttaacac acaattacct
     4561 tccacaatgg catattccgc cacctgtgaa ctgtaatgaa tcgtcggaat ggcatcttct
     4621 tctatgccag ctttcacctg cgcgtgaccg taaactttag cgcaatcgca tagccagacg
     4681 ttgttctctt cattaccttc aatactggca aaatcaaaaa cttcggcgcg atgttcaata
     4741 aaagcatacc ggacgacggc atcgccataa atttgtgcct ggtggacaat acgcgaggcg
     4801 ctaacctttg cgcgatcata aatttgtagc aggagttgat ggtcgggcgt taagccttgt
     4861 gcggcgacga tcatagaatg ttgatcaatt aaggcgtgac caaatattct acattgaccg
     4921 caaactaatg agtcactaat ggtgacactg tcacttatat atgcaccctg gctgatttca
     4981 ctattatcga tccagacatt atccgttgcg taaacctctc cccacagcac gctggtgccg
     5041 gtgatacgcg tattcccgga aatcaccgtt ccgccgaacg caatagcatt ctggtcgtaa
     5101 atccagcaat ttccttcctg tgctaacacc gtttcgcgat cgatccagcc gccagcgctt
     5161 cctgctatca catcgttaaa atcgctcatg gcgataattt gccgtaataa cacacttttt
     5221 ttagtgccat cttcctgata actaaaggct cgctgttctt cacttagacg atatttacgc
     5281 atagcgtttt cccacaggtg acttactata accgtagcaa attctgcggc tctggctatg
     5341 ctcgagaaaa ttccataaaa tgcatttcaa atatacttta taaattaaac aaaatgagta
     5401 agaagatgca gaacgataaa gtgctcaatt tgccggcagg ctactttggt attgtgttgg
     5461 ggacgatagg gatgggattt gcctggcgct atgccagcca ggtttggcag gtcagccact
     5521 ggttggggga tgggctggtg attctggcga tgatcatctg gggattattg actggcgcat
     5581 ttattacccg actcatacgc tttccgcata gcgtgctggc agaagtgcgc catccagtgc
     5641 tgagcagttt tgtgagtttg tttccggcaa cgacgatgct ggtggcgatt ggttttgttc
     5701 cgtggtttcg cccactggcg gtgtgcctgt tcagttttgg tgtcgtggtt cagttggctt
     5761 atgccgcctg gcaaactgcg ggattatggc gtggatctca ccctgaagaa gctaccacgc
     5821 ctggactgta tctgccgaca gttgccaaca actttatcag cgcaatggcc tgtggtgcgt
     5881 tgggctacac cgacgccggt ctggtgtttt taggcgcagg cgttttctca tggctaagcc
     5941 tggaaccggt gatcttgcag cgtctgcgca gttcgggaga attacccacg gcactgagga
     6001 catcactcgg cattcagctc gctcctgcgc tggtggcctg tagtgcctgg ctgagcgtca
     6061 acggcggcga gggtgacacg ctggcgaaaa tgcttttcgg ttatggactg ctgcaactgc
     6121 tgtttatgct atgtctgatg ccatggtatc tctcccagcc atttaatgct tcattctgga
     6181 gtttctcgtt cggcgtatct gcactggcaa ccaccggttt gcatctgggg agtggcagcg
     6241 ataatggatt tttccatacg ctggcggtgc cgctgtttat ctttaccaat tttattattg
     6301 caatactgct catccgtact tttgcgcttc tgatgcaggg aaaattgtta gtcagaaccg
     6361 agcgcgccgt tttaatgaaa gcagaggaca aagaatgatc attcgtgatg aaaactattt
     6421 tactgataaa tatgaattaa cccgcacaca ctctgaagtg ctggaagcgg tgaaagtggt
     6481 taaaccgggt aaaacgctgg atctgggctg tggcaatggt cgtaacagtc tttacctggc
     6541 agccaatggt tatgatgttg acgcatggga taaaaatgcc atgagtatcg ccaacgtcga
     6601 gcgcattaag tccattgaaa atctggataa tttacacacc cgggtcgttg atctgaataa
     6661 cctcacattt gatggacagt acgattttat tctttcgact gtggtgctga tgttccttga
     6721 ggctaaaacc atcccagggc tgattgccaa tatgcaacgt tgcgctaaac ctggcggtta
     6781 caacctgatt gtggcggcga tggataccgc tgattatcca tgtaccgtcg gcttcccgtt
     6841 tgccttcaaa gagggggaat tacgtcgata ttacgaaggc tgggagatgg tgaaatacaa
     6901 tgaagacgtc ggcgagctgc accgcaccga cgccaacggt aatcgtatta aactgcgttt
     6961 cgccacgatg ctggcacgta aaaaatgatc cggtaagaac aaagcgcgtg aaaattcccc
     7021 acgctgagat ggtttactgt tcttcttttc ggtaagcata ttttttatcg aagggatgtg
     7081 aaattaatca cagtagtcga agttttttag ccgcttaacg tactgaaatt taactactga
     7141 tgattgactt agcccctttt tcggcattga ctatgtcgtc tgaaaagggg ctaaaaaatt
     7201 tattttcacc aacacttttt ttgccacaac acgaagcggc gctttttgct ataacttaaa
     7261 aagtaatata atcatctcag gaaactattc atgcgtacca catcatttgc gaaagttgca
     7321 gctttatgcg gcttgttggc tctgtctggt tgtgcctcta aaatcaccca gccagataaa
     7381 tattctggtt ttttaaacaa ttactctgat ttaaaagaaa caacctcggc aacaggtaaa
     7441 cctgttttac gttgggtaga cccgagtttt gatcaaagca aatatgacag catcgtctgg
     7501 aacccaatca cttattatcc ggtaccgaaa ccttctaccc aggtagggca gaaagttctg
     7561 gataaaattt tgaactatac caacaccgaa atgaaagaag cgatagcgca gcgtaaacca
     7621 ctggttacca ccgctgggcc gcgtagtctg attttccgtg gggccattac cggtgtagat
     7681 accagcaaag aagggctgca attctatgaa gtggttcctg ttgcattagt ggttgcgggg
     7741 acgcaaatgg ctacaggcca ccgtaccatg gatactcgct tgtattttga aggtgagctg
     7801 attgatgcag cgactaataa accggttatc aaagtcgttc gtcagggcga aggtaaagac
     7861 ctgaataacg aaagtacgcc aatggctttc gaaaatatta aacaagttat tgatgacatg
     7921 gcgaccgatg ccaccatgtt tgacgttaac aaaaagtagt tccagacgcg ccatcgttag
     7981 atggcgcttt ttattatcgg tttctgttag cgattaaatt caacaccacg taacaaacgc
     8041 ctccggcaat taatccccaa aacgcagaac caatcccgaa cagcgtcaat ccacttgccg
     8101 ttaccagaaa tgccaccacc gccgcgtcgc gctcacgctc attatgcagc gcctgataca
     8161 aactgccgcc aatggtactc aacagcgcaa gacctgccag catctggatc caacttacgg
     8221 gcagggcagc catcatcccg gtaatggcac taccaaacag acctgcgatc aaataaaaaa
     8281 tgccggcaac ggcagcggcc agccaacgtt gatctttatc cggatgcgct tccgggcttt
     8341 ggcaaatagc cgcggtgatt gccgcaatac cgacggaata aacgccgaaa ggggaaaaaa
     8401 acagtgccag caatccagta aacacaatca acggcgaaac aggagccgaa tacccggctg
     8461 ctttcattgc tgcgataccc ggtgcgtttt gcgatgccat cgtcaccaga aaaaggggga
     8521 gtgcaacgct cagactgtga gcaaacgaaa aatcaggggt aatataagtg gggagaacgg
     8581 gtttaaagac aatatcagtt gtaacaacgt caccttgcgc ggtaacgatg acgatcccaa
     8641 taatcatcgc ggcaattacc gcatagcgcg gcgcaacggc cttggctgcc agccatgcca
     8701 gcaacatact gccacacaac gtaaattgac catccagact ggcaaacgcc tgtaaaccaa
     8761 aacgtaataa aatcccggca agcattgccg ccgcaagcga gtgcggaata atgcgcatca
     8821 gacgagcaaa gagtcccgtt atgccgcaga ggactattaa cgcgttggtg acaataaaaa
     8881 cgccgatggc ttcgttaagt gttagttcct gcaatccggt gaccaacaaa gccgcgccag
     8941 gcgttgacca tgcggtgaga acaggtacgc gataccataa tgtcagagtc agcgtactga
     9001 cgcccattgc cagccccagc gccgtcatcc agccagagat ttgtgcagtg gtggctccgg
     9061 cgacaatcgc tgcttgccag attattgccg ctgaactggc gtagccaatt aataccgcca
     9121 gaaaccccgc cagtagcgtg ggtggaggaa tagaaaacag acgcatagtc acctcgtgcg
     9181 ttataacgta caggtaccgt agcatttgtc cgttataacg cacaagtgat aaacttccgt
     9241 tttgccggag gagtcgcatg gaaaatctcg ctcgtttttt atccaccaca cttaaacaac
     9301 tacgtcagca gcgcggctgg agtctttcgc gactggcaga agcgacgggc gtttctaaag
     9361 cgatgttagg gcagattgag cgtaatgaat ccagcccgac ggtcgcgaca ttatggaaaa
     9421 ttgccaccgg gttgaacgtg ccattttcaa catttatttc tccgccgcag tccgctacgc
     9481 cttcagttta tgatccacaa cggcaggcga tggtgatcac ttcgctgttt ccttatgatc
     9541 cacaactctg ctttgaacac ttctcgattc agatggcacc cggtgcaata agcgaatcga
     9601 tgccccatga aaagggggta atcgaacatg tcgtcgtcat tgatggacaa cttgatctgt
     9661 gtgttgatgg tgaatggcag agccttaatt gtggggaagg cgttcgattt gctgcagacg
     9721 tcacgcatgt ctatcgtaat ggtggggagc aaaccgtaca ttttcattcc ctcatccatt
     9781 acccgcgcag ttaagcggga aaactatttc gcaacgtcgc gcttgtggct aaaatagccg
     9841 ccatttttca gctactggat aagaaagtga ccgtatcttc tcatcgtctt gaactgttaa
     9901 gcccggcacg cgatgccgcc attgcccgcg aagctatttt gcacggtgcc gatgctgttt
     9961 atatcggcgg ccctggtttt ggtgcccgtc ataatgccag taatagcctg aaagatattg
    10021 ccgagttggt gccgtttgcc catcgttatg gtgcaaaaat tttcgtcacg cttaacacca
    10081 ttttgcatga tgatgagctg gaacccgcgc aacggctgat tactgacctc taccagaccg
    10141 gtgtcgatgc gctgattgtt caggatatgg ggattctgga acttgatatt ccgccgattg
    10201 aactgcacgc cagtacgcag tgcgatattc gtacagtaga aaaagcgaag ttcctctctg
    10261 atgttggctt cacgcagatt gtgctggcgc gagaactgaa tcttgagcag atccgcgcga
    10321 ttcaccaggc cacgaacgcg accattgaat tctttattca tggcgcattg tgcgtggcct
    10381 attcgggtca gtgctacatt tctcatgcgc aaacagggcg tagcgccaac cgtggcgatt
    10441 gctcgcaggc gtgccgtttg ccatacacat tgaaagacga tcaggggcgg gtggtttcct
    10501 atgaaaaaca tctgctgtcg atgaaagata acgatcagac tgccaacctc ggcgcgctga
    10561 ttgatgctgg cgtacgctcc ttcaagattg aagggcgtta caaagatatg agctacgtga
    10621 agaatatcac cgcccattat cgccagatgc tggatgccat tattgaagaa cgtggcgatc
    10681 tggcgcgcgc ttcatcaggt cgtactgaac atttctttgt tccatcgacg gaaaagactt
    10741 tccaccgtgg tagcacagat tattttgtga atgcccgtaa aggcgatatt ggcgcgttcg
    10801 attcgccgaa atttatcggc ctgccggtgg gcgaagtatt gaaagtagcg aaagatcata
    10861 ttgatgttgc cgttaccgag ccactggcaa atggcgatgg cctgaacgtg atgattaaac
    10921 gtgaagtcgt cggttttcgt gccaatacgg tagagaaaac cggagaaaat cagtaccgcg
    10981 tctggccaaa tgaaatgcca gcagatttgc acaaaattcg cccgcatcac ccactaaacc
    11041 gtaatcttga tcataactgg caccaggcac tgacaaaaac ctccagcgaa cgtcgggtgg
    11101 cggtagacat tgaactgggc ggctggcagg aacaactgat tctgaccctg accagtgaag
    11161 agggcgtcag cgtcacgcat acgctggacg ggcagttcga cgaagccaat aacgccgaaa
    11221 aagcaatgaa caatctgaag gatggtctga caaaactggg gcaaaccatc tattacgccc
    11281 gcaatgtgca aattaatttg ccgggggcgc tgtttgtacc aaacagtctg ttaaaccagt
    11341 tccgccgtga agccgccgat atgcttgatg ctgcgcgtct tgccagttac cagcgcggca
    11401 gccgtaaacc ggttgctgat cctgcgccgg tttatccgca aacgcatctg agtttcctcg
    11461 cgaacgtata caaccagaaa gcgcgtgaat tttatcatcg ctatggtgtg caactgattg
    11521 acgcggcgta tgaggcacat gaagagaagg gcgaagtccc ggtgatgatc accaagcatt
    11581 gtctgcgctt tgccttcaat ctgtgcccga aacaggcgaa aggcaatatc aaaagctgga
    11641 aggcgacgcc aatgcaactg gttaacggcg atgaagtatt aacgctaaag tttgattgcc
    11701 gcccatgcga gatgcacgtc attggcaaaa tcaaaaatca catactgaaa atgccgttac
    11761 cgggaagcgt agtggcatcc gtaagtccgg atgatctgct gaaaacattg ccgaagcgaa
    11821 aagggtaaaa cgccagtttt cgggttactc accactcatc aaatctgcat gatattgcct
    11881 gccgggtaag gcgtcatgcc gcatccggca acaaatgact caacgctgtc ccgcttctgg
    11941 tttgcgcgat ttttgccagt aaaaatgctc gcgcaaacct tccgccgact cttccgccac
    12001 agcacgcaat tcatcgctgt ccgcttcatg acgcagctga tgatccacat tctttaccca
    12061 cataaattca tgtcctttgt gccctgccat gagttgtcct gagaacagtg cacacgttaa
    12121 taagacaacc gataacgcct tcgaaaacat cccgccacct ttttctaacc ttttgccgct
    12181 atgatgccga tcgtttcttg aggttattat tcagttttgc aaattagagc aaagaaattc
    12241 tggaatcttc cttcctgatt ttgcattgaa ttctgccgtt gcggcgattt agtgctattt
    12301 tcgagcacat tacacacgga ggtaaacttc gccattaaat agtcacgatc actttattga
    12361 agtgcctttg agcgtcgcct ctaatgtatt gctgttaaat gcttttttac agtcagaaat
    12421 cactcagcaa gagttagcca ggcgaattgg caaacataaa caggagatta ctcgcctatt
    12481 taatttgcac catgcgacaa aaatcgacgc cgtccagctc gcggctaagg cgcttggcaa
    12541 agagttatcg ctggtgatgg tttaattaca gttaacgaaa agttgtcatt tttaacaact
    12601 gatatagact gccgaatcat ctgcacataa ttacgattcg ataatgaaaa aataccagca
    12661 gcttgcagaa caattacgcg agcagattgc gtcgggtatc tggcaacccg gcgatcgttt
    12721 gccttcgttg cgtgaccagg tggcgctttc tggcatgagc tttatgactg tcagccatgc
    12781 ctatcagttg ctcgaaagtc agggatatat tatcgcgcga ccgcaatcgg gttattacgt
    12841 tgcgccacag gcaataaaaa tgccgaaagc gacagtcatt ccagtcacac gagatgaagc
    12901 agtcgatatc aacacctata tttttgatat gttgcaggcc agtcgcgatc cgtcggtagt
    12961 tccgtttgcc tcggcctttc ccgacccgcg acttttcccc ctccaacaac taaaccgctc
    13021 gctggcgcag gtaagcaaaa ccgccacggc gatgagcgtg attgaaaact taccgccagg
    13081 aaacgcagaa ctgcgtcagg ctattgctcg tcgctatgcc ttacagggca tcaccatttc
    13141 tcctgatgaa attgtcatta ccgccggggc gttagaggca ttaaacctca gtttgcaagc
    13201 ggtaactgaa ccgggcgatt gggtgatagt agagaatcct tgtttctacg gcgcgttgca
    13261 ggcgctggag cggttacggc tgaaggcgtt atcggtagcg acggatatta aagaagggat
    13321 cgatcttcag gcgctggaac tggcgttgca ggagtatccg gtgaaagcgt gctggctgat
    13381 gactaatagc cagaacccac ttggatttac cttaacgccg cagaaaaaag tgcggctggt
    13441 agcgttgctc aatcagtaca acgtaacgct gattgaagat gacgtttata gcgaacttta
    13501 ttttggacgg gaaaaaccgc tgcctgcgaa agcgtgggat cgccacgatg gtgttttgca
    13561 ttgctcttcg ttttcgaaat gtctggtgcc tggttttcgt attggttggg tcgccgccgg
    13621 aaaacatgca cgtaaaattc aacgcttgca gttgatgagt acgctttcca ccagctcacc
    13681 gatgcagctt gcgctggtgg attacctttc tactcgccga tacgatgctc atcttcgtcg
    13741 cctgcgtcgc cagcttgcgg aacgtaaaca acgcgcctgg caggctttgc tgcgttatct
    13801 gcctgcggaa gtcaaaattc atcacaatga cagcggttat tttctctggc tggagctccc
    13861 cgagccgtta gatgcaggag aattaagcct ggtggcactg acgcatcata tcagtattgc
    13921 gccgggtaat atgttttcta ccggtgaaaa ctggtcacgt ttttttcgtt ttaataccgc
    13981 gtggcagtgg ggagaacgtg aagaacaggc ggtaaaacaa ttaggcaaac ttattcaaga
    14041 acggctgtaa tagcgtttaa tttaattcct ctcaggttgg gtaatatgaa tttcgaatag
    14101 cagtcatata tcctaactcc ttgtctatac tccagaagat aaccttacag acggcataat
    14161 gcgcggtagc tcacaacctg attaaatttt ctcagggccg aaggtgtgcc tgcaagccgc
    14221 cgtctatggt taaacaagga gatattttta cggcacggcg gctgaacaat taattacgac
    14281 aggagtaaga ccttatgagc aagacatttg cccgcagcag cctgtgtgcg ctcagcatga
    14341 caataatgac cgctcacgcc gccgaaccgc ctaccaattt agagaatccg gaagggcgac
    14401 tggatattat cgcctggccg ggatacatcg aacgcggaca aactgataaa cagtacgact
    14461 gggtaacgca attcgaaaaa gagacaggct gcgcggtgaa tgttaaaacc gccgcgactt
    14521 ccgatgaaat ggtcagtctg atggccaaag ggggttacga tctggttacg gcatccggcg
    14581 atgcctcgct gcgtttgatt atgggcaaac gcgtgcagcc aattaatacc gccttgattc
    14641 ccaactggaa aacgctcgat ccgcgcgtgg ttaaaggcga ctggtttaac gttagtggca
    14701 aagtttatgg cacaccttac caatggggtc cgaacctgtt gatgtacaac actaaaacct
    14761 tcccgacgcc gccggatagc tggcaagtgg tttttgttga gcagaatctg ccggacggca
    14821 agagcaataa aggccgcgtt caggcttatg atggccctat ctacattgcg gacgctgcgt
    14881 tgttcgttaa agccactcag ccgcagttgg gcatcagtga tccgtatcaa ctcaccgaag
    14941 aacagtacca ggcggtgctg aaagtgctgc gcgatcaaca tagtttgatc catcgctact
    15001 ggcatgacac taccgtgcaa atgagcgatt tcaaaaacga gggtgtggtt gcttccagtg
    15061 catggcccta tcaggccaac gccctgaaag ccgaaggcca gcctgtcgct accgttttcc
    15121 cgaaggaggg cgttaccggt tgggctgaca ccaccatgct acatagcgaa gcgaaacatc
    15181 cggtttgcgc ctacaaatgg atgaactggt cattaacccc aaaagtgcag ggcgatgtgg
    15241 cggcctggtt tggctcgtta ccagtagtgc cgcaagggtg taaagccagt ccgttattag
    15301 gcgagaaagg ttgtgaaaca aacggtttta actatttcga taaaatcgcc ttctggaaaa
    15361 cgcctgtagc agaagggggc aagtttgttc cctacagtcg ctggacgcag gattacattg
    15421 ccattatggg cggtcgctaa cttcgctggg gtgttttatg acgtacgcag tggagtttga
    15481 caacgtctca cggttgtacg gtgacgtgcg cgcagtagat ggcgtcagta ttgcgataaa
    15541 agatggtgag ttcttctcta tgctggggcc gtccggctcc ggcaaaacca cttgcctgcg
    15601 cctgattgct ggattcgaac agctttccgg cggggctatc tctatttttg gtacgcccgc
    15661 cagcaatctg ccaccgtggg agcgggacgt gaatactgtc ttccaggact acgcgctatt
    15721 tccgcatatg tcgattcttg acaacgtagc ctacgggctg atggtcaaag gcgtgaataa
    15781 aaagcagcgg catgcaatgg cgcaagaggc gcttgagaaa gtggcgttgg ggtttgtaca
    15841 gcaacgtaaa ccgtcacaac tttctggtgg tcagcgccag cgggttgcta tcgccagagc
    15901 actggtgaac gaaccgcgtg tgttgttgct ggatgaaccg ctcggcgcgc tggatctcaa
    15961 attgcgagag caaatgcagc ttgagctgaa aaagctgcaa cagtctctcg gtatcacttt
    16021 tatcttcgtt acccacgatc agggcgaagc gttatcgatg tccgatcggg tggcggtttt
    16081 caataatgga cgcattgaac aggtcgattc tccgcgcgat ctctatatgc gcccgcgcac
    16141 gccgtttgtt gcgggattcg tcgggacatc caacgttttt gatccgctaa tggccgagaa
    16201 actttgtggc atgacgggaa gcttcgcact acgaccggaa catatccgcc tcaacaccca
    16261 tggcgaaatg caggctaatg gcacgatcca ggcggtgcaa tatcagggcg cagcgacccg
    16321 ttttgaactg aaattgaacg gcggtgaaaa actgctggtg agtcaggcca atatgacagg
    16381 cgaagagcta cctgccacgc tcacgcccgg acaacaggtg atggtttcct ggtcacgtga
    16441 tgtgatggtg gcgctggttg aggagaggtg aatggcgatg aacgtattgc aatcaccttc
    16501 acgtccaggt ctgggtaagg tgtccggttt cttctggcgt aatccggggc tggggctgtt
    16561 tttgctgctg cttggcccgc taatgtggtt tggcattgtc tatttcggct cgctgctgac
    16621 gctgttatgg cagggctttt atacctttga cgatttcacc atgtcggtaa cgccggaact
    16681 gacgctggcg aatatccgcg cgctgtttaa tccggcgaat tacgacatca ttgtccgcac
    16741 gctgaccatg gctgtggcag tcactatcgc cagcgccatt ctggcttttc caatggcgtg
    16801 gtatatggcg cgctatacca gcgggaaaat gaaagcgttt ttttatatcg cggtaatgtt
    16861 gccgatgtgg gcgagctaca ttgttaaagc ctatgcctgg acgttattgc tggcaaaaga
    16921 tggcgtggcg cagtggtttt tacaacatct ggggctggaa ccactgctga ctgcgttcct
    16981 cacgctaccg gcggtgggag gtaatacgct gtcaacttcc gggctggggc gctttctggt
    17041 gtttctctat atctggttgc cgttcatgat cctcccggtg caggcggcgc ttgagcgttt
    17101 gccgccgtca ttgttgcagg cgtcggctga tcttggcgca cgtccacgac aaacctttcg
    17161 ctatgtggtg ctgccgctgg caatcccggg tattgccgct ggctctatct ttaccttctc
    17221 actcacgctg ggcgatttta ttgtcccgca gctggttggc cctccaggat attttatcgg
    17281 caatatggtt tattcccagc agggggcgat tggcaatatg ccgatggcgg cggcattcac
    17341 cctggtgccg attgttctca tcgcacttta cctggcgttc gtgaaacgtc tgggagcgtt
    17401 cgatgcactc tgaacgcgca ccgtttttcc tcaaactggc ggcctggggc ggcgtggttt
    17461 tcctacattt tcccatcctg attatcgctg cctatgcgtt taacactgaa gatgcggcgt
    17521 ttagttttcc accgcaaggc ctgacgctgc gctggtttag cgtggcagca cagcgtagtg
    17581 atatccttga tgccgtgaca ctgtcactta aagtggcggc gctggcgaca ttaatcgcgc
    17641 tggtgttagg gacgctggca gctgccgcgc tgtggcgacg agactttttc ggcaaaaacg
    17701 ccatttcgct gttactgttg ctgcccattg cgctgccggg cattgtcact ggtctggcgc
    17761 tattaaccgc ctttaaaacc atcaatctgg agccaggatt tttcaccatc gtggtcggtc
    17821 atgcgacttt ttgcgtagtg gtggtgttta acaatgtcat cgcccgtttt cgccgcacct
    17881 cgtggagtct ggttgaggcg tcaatggatc ttggggccaa tggctggcaa accttccgct
    17941 acgtagtgtt gccgaatctc agttcggcgt tactggctgg aggaatgctg gcgtttgcct
    18001 tgtcgttcga tgaaatcatc gtgacgactt ttacggcagg tcatgaacga acgttaccgt
    18061 tgtggttgct caatcagctt gggcgaccgc gtgatgtacc ggtaaccaac gtggtggcac
    18121 tgctggttat gttggtaaca accttgccga tcctgggggc ctggtggcta acccgcgaag
    18181 gcgacaatgg tcaataacca ctgatacagg aatatgctat gcaacataag ttactgatta
    18241 acggagaact ggttagcggc gaaggggaaa aacagcctgt ctataatccg gcaacggggg
    18301 acgttttact ggagattgcc gaggcatccg cagagcaggt caatgctgct gtgcgcgcgg
    18361 cagatgcagc atttgccgaa tgggggcaaa ccacgccaaa agcgcgtgcg gaatgcctgc
    18421 tgaaactggc tgatgttatc gaagaaaatg gtcaggtttt tgccgaactg gagtcccgta
    18481 attgtggcaa accgctgcat agtgcgttca atgatgaaat tccggcgatt gtcgatgtct
    18541 ttcgcttttt cgccggtgcg gcgcgctgcc tgaatggtct ggcggcaggt gaatatcttg
    18601 aaggtcatac ttcgatgatc cgtcgcgatc cgttgggggt cgtggcttct atcgcaccgt
    18661 ggaattatcc gctgatgatg gctgcgtgga aactggctcc ggcgctggcg gcagggaact
    18721 gcgtagtgct taaaccatca gaaattaccc cgctgaccgc gttgaagttg gcagagctgg
    18781 cgaaagatat cttcccggct ggcgtgatta acgtgctgtt tggcagaggc aaaacggtgg
    18841 gcgatccgct gaccggacat cccaaagtgc ggatggtgtc gctgacgggt tctatcgcca
    18901 ctggggaaca catcatcagc cataccgcgc cgtccattaa gcgtactcat atggaacttg
    18961 gtggcaaagc gccagtgatt gtttttgatg atgcggatat tgaagctgtg gtcgaaggtg
    19021 tacgtacttt tggctattac aatgccggac aggattgtac tgcggcttgt cggatctacg
    19081 cgcaaaaagg catttacgat acgctggtgg aaaaactcgg tgctgcggtg gcaacgttaa
    19141 aatcgggttc gccggatgac gagtctacgg agcttggacc tttaagctcg ctggcgcatc
    19201 tcgaacgcgt cagcaaggcg gtagaagagg cgaaagcgac agggcacatc aaagtgatca
    19261 ctggcggtga aaagcgcaag ggtaatggct attactatgc gccgacgctg ctggctggcg
    19321 cattacagga tgatgccatc gtgcaaaaag aggtatttgg tccggtagtg agtgttacgc
    19381 tcttcgacag cgaagaacag gtggtgaact gggcgaatga cagtcagtac ggacttgcat
    19441 cttcggtatg gacgaaagat gtgggcaggg cgcatcgcgt cagcgcgcgg ctgcaatatg
    19501 gttgtacctg ggtcaatacc catttcatgc tggtaagtga aatgccgcac ggtgggcaga
    19561 aactttctgg ttacggcaag gatatgtcac tttatgggct ggaggattac accgtcgtcc
    19621 gccacgtcat ggttaaacat taaggataat attgcagatc gtaagagtat gagatgatct
    19681 tgcgtactgt cagagcactg atttctctga cagtacgtgc tgcgtgcaaa atcactacat
    19741 caaataaacc agccaaatct catagagata agagtaaaca aaccaacagc agcaaagaca
    19801 tttatcagta ctacagttct actggaaaca ttcatttttg ccacctttta tcattgcccc
    19861 tatgtgtata gtacgggtta agaaaatccg caataatact cattctgaag atggataagg
    19921 gcaagttgct gtttgatgat tttttctcaa actggtgaaa aaaacttgat gcacgtcaaa
    19981 aaatgacgca tatttgcgcg cgttttattc atctggctgg acgcccgtac atgtctctct
    20041 atcaacacat gcttgttttc tatgcggtta tggcagcaat cgcatttctt atcacctggt
    20101 ttctttctca tgataagaaa cgcatccgtc tcttaagcgc ctttctggtg ggggcaacat
    20161 ggccgatgag tttcccggtg gcgctgttgt tttctctgtt ttaaatctta tgcactggct
    20221 tgacggcacc acgcagactt atatcatttg gatgaatcga taaatttcac aagtggctaa
    20281 ggagaaagta tgtcgcatct ggatgaagtc atcgcgcgcg tggatgccgc gattgaagag
    20341 agcgtcattg cccatatgaa cgaattatta atcgccctga gcgatgacgc ggagttaagt
    20401 cgggaagatc gctacaccct gcagcagcgt ttgcgcaccg ctattgctca tcacggtcgc
    20461 aaacataaag aagatatgga agcgcgccac gaacagttaa ccaaaggcgg taccatcctc
    20521 tgattaaaat gagcgtctgg ccaccagcca ggcgccaacc acaagtaaaa ttgcgccaca
    20581 aattgggccg atcaacgccc gaagtggtac gccatggctg cggaagatat ccagcaccag
    20641 accgccaatc agctggctgg cgaccagtac tgcaatagtt gtcgccgctc ccacattctg
    20701 atatccgctg atactggcga agacaaaaaa cgatcccagc aagccaggta taagtgtcca
    20761 ccagcgcacg ctggacacca gttcgccaaa ccccgccatg ccttgtttaa accataaaat
    20821 agaaacaaag agcacaatcc ccaccagtga gttcagcaac atggcgatga gaatggtaga
    20881 ggaggtctgg gtgatgcgca ccatcagcgt gttctggact accagaccaa tcccggctgc
    20941 aatcaaaaag gcaagggtaa gtgactgatt catccaatcg cgtccggttc agtgcgctcg
    21001 tcgagttgca actgcataaa tgtcagatcc agccagcgcc caaatttagt gcctacctgc
    21061 ggcatttgcg cggtgacgac aaatcccagc gactggtgca gatgcagcga ggcctgattt
    21121 tgcgattcga tcccggcgac catgacatgc ttcccgcaat cccgcgcttc atcaattaat
    21181 cggcttaaca atttacgccc cagacctttc ccctgatgat cgggatggac ataaaccgaa
    21241 tgttccacgg tatggcgaaa accatcaaaa ctacgccagt cgccaaacga ggcatatccc
    21301 gtcactacgc catcttcttc actcaccagc accggataac ctgctatggt ccgcgcttca
    21361 aaccaggcaa tgcggttatc cgcatccacc gtttggtcat tccagatagc cgccgtatac
    21421 aacacggcgt ggttataaat ttccgcaatt gcagcacagt cggctttgcg ggcaaaacgg
    21481 atggacatgt ctggcctcga taaaataatg atgatgatgt tatcaatact atcgaaaaca
    21541 gcccgaagca acggattcct ctatgaaatt attgcgtgtt gcagagggga tgtgacggct
    21601 gcaaacaaaa ccaatcctgt gagcctgcta ctattgatgg attcatgcca aaagcacagg
    21661 agagcattat ggggcaacaa acgcagcgta accgatgttg ggttctgtcc tcgcgtccgc
    21721 atggcgcgcc ggttccttac gtctggtttc ggtaaatgcg ctctttgtcg caccagcgca
    21781 agcatttaca gttccggaag tgggaaaacg tcaattaaat gaaatcaatc ggatccgcta
    21841 cgaactggag ttaatggcag ttgctctggc tgtcgaaaac ctcactatgc aaaaaaacgt
    21901 tgctatgttg tgccagcaat acagccgata aataaaatac gcccggcaaa taccgggctt
    21961 aaagataatt actcaaatcg ccacgcaata tttatgccga caccataatt tcgtccgggc
    22021 gcaggttcgt aatatcgccc gtttgactca ttgacaatga cagaaccaac gtattcttta
    22081 tcgaataaat tatcgacacg accaaataaa tccacggtta aattgtggta attgtattta
    22141 tacccggtga ataagccgac gagtgtataa gaaggcgctt tggccgtatt ttcatcatct
    22201 gccataatat cgcccatata acgcgcttcc gtgcctgcat accaaccatc ttccggtata
    22261 taacctatcg acgcaaagcc catattacgg gcgatccctg gcatccggtt accgttacaa
    22321 tcctgttcat tgcagacatt gctgcgatag gtcgcatcaa gccaggtcca ggacgctttt
    22381 acgcgaaaat ctcccgcgaa acgttgatcc catgccagtt cagcgccttg acgacgggtc
    22441 tttccggcat ttttgtaagt cgtacgccca ccgctactgc tatcgacaac aatttcatca
    22501 tcggtgtcgg tctggaacaa tgcgagacta agcagtccat caccaatacg cgttttactg
    22561 ccgatctcaa ttgtatcgtt ggtggagggt tttaaaccaa agttcatacc gctttgtcca
    22621 tcagcgcgat aagacagttc attaatcgtc ggcgtttcaa aaccgcgccc ggctgccaga
    22681 tagacattcc aggcatcggt cattgcatat tttaacgatc cggcaggtag ccatttgtga
    22741 taactggcat caccgctgtc atcgccgtta cccggagtaa cgtaatgatc gttggaatca
    22801 aaccacacgg agctgtagcg cacgccagca tccagcgaaa gtttgtcggt cagttgccac
    22861 tgggtttgta aatagggatc gacgttccac atcaaattgc gttcgtcgcg gcgcaactca
    22921 cctttttgcc cgtattccgg cacgccgcga ttcaggcgga agttattgta acccttgcgg
    22981 ttttcactca tgttttcgta gttcaggccg gttgtgaacg tgactggaac gcccagttca
    23041 ccacggtgtg tccagcggct gtctatcccc tggtaatggc gttgcagggt aatcacgccg
    23101 cccgcatgtg acgggttaag ttgcggggcc atggggattg actggtactg ggtcgtttct
    23161 cgctctccgg catacatcat cacactcata tcatcttgtg cgctcaggct acgctcatag
    23221 cgcaacccag cctgagtttg cttgatggtt tttcgcatgt cgtactgttc tgcacgaggc
    23281 gcttgttgtg gattcgcctt ccattctgct tcggttagcc cacctgggtc atctgctttg
    23341 atatccacac tattgaaaat caggcttaat ttgctggcgt catcaatgcg tacgcccagt
    23401 ttggcattgg ctaaattttt ctgtgcgcca ctatggtcac gatagccgtg ggtcgtaaaa
    23461 cgtgtggttg cgacggtgta atcgacatcg ccgggttgtg tgccgtcgcc cgttgcgccc
    23521 gttgctttca gcccatagcg ccagctgcca aaactgccgt agtaactact ggcttcaatg
    23581 gttggtggct gttgtccggt ctgggtggtg acattcatta caccgccaga cgcgttgcca
    23641 tacagagcag agaaggggcc acgcagcact tccacatttt gcacactgct taaatcgatg
    23701 ttagatgtct gcccttgtcc gtcgggcatg gtagcgggaa taccgtccac atacaggcga
    23761 ataccgcgaa ttccgtaagt ggagcgggag ccaaatccgc gaatcgacag ctgtaaatct
    23821 tgcgcatagt tctgtcggtt ttgtacctgt aaaccaggca ctccggtcag tgattcagac
    23881 aagttaatgc gcggtgttgc caggcgcatc tcctcgccat ccaccacgct cacggctgct
    23941 ggggtatcca gttctgaaac cacctgcggt gcggcactga caatcatggt ctgttcatca
    24001 gcggcaaaaa caacggggga aaggacaagc agtgcgggca aaacggtctg tcggacggaa
    24061 aaaatcttca tgaaaaaagc caggttaaga atgggaaaac accgtcatgg taataaaatt
    24121 gtaaatttat ggaaaacaaa acggcacaat acgttaagta attgagaaaa ttgtagtcat
    24181 aacggtaaga aatgctccac atttgagaaa ataatgatta ccattcccat ttataacaag
    24241 ggcgtaacga tgattacgct tagcgaagca ttgtgaagca gcaaaaatat cggttcatca
    24301 aagggagtcg tcatgcattt acgtcatctg ttttcatcgc gcctgcgtgg ttcattactg
    24361 ttaggttcat tgctcgttgc ttcatcattc agtacgcagg ccgcagaaga aatgctgcgt
    24421 aaagcggtag gtaaaggtgc ctacgaaatg gcttatagcc agcaagaaaa cgcgctgtgg
    24481 attgccactt cgcaaagccg caaactggat aaaggcggcg tggtttatcg tcttgatccg
    24541 gttactctgg aagtgacgca ggcgatccat aacgatctca agccgtttgg tgccaccatc
    24601 aataacacga ctcagacgtt gtggtttggt aacaccgtaa atagtgcggt cacggcgata
    24661 gatgccaaaa cgggcgaagt gaaaggacgt ctggtgctgg atgatcgtaa gcgcacggaa
    24721 gaggtacgcc cgttgcaacc acgtgagctg gtagctgacg ataccacgaa caccgtttac
    24781 atcagtggta ttggtaaaga gagcgtgatt tgggtcgttg atggcgagaa tatcaaactg
    24841 aaaaccgcca tccagaacac cggtaaaatg agtaccggtc tggcgctgga tagcaaaggc
    24901 aaacgtcttt acaccactaa cgctgacggc gaattgatta ccatcgacac caccgacaat
    24961 aaaatcctca gccgtaaaaa gctgctggat gacggcaaag agcacttctt tatcaacatc
    25021 agccttgata ccaccaatca gcgtgcattt atcaccgatt ctaaagcggc agaagtgtta
    25081 gtggtcgata cccgtaatgg caatattctg gcgaaggttg cggcaccgga atcactggct
    25141 gtgctgttta acccagcgcg taatgaagcc tacgtgacgc atcgtcaggc aggtaaagtc
    25201 agtgtgattg acgcgaaaag ctataaagtg gtgaaaacgt tcgatacgcc gactcatccg
    25261 aacagtctgg cgctgtctgc cgatggcaaa acgctgtatg tcagtgtgaa acaaaaatcc
    25321 actaaacagc aggaagctac ccagccggac gatgtgattc gtattgcgct gtaatagata
    25381 tggcgagggt gaaaacggaa agaattgcct gacttttatc acgccgcatc cggcaccttc
    25441 gtcagtagtc tgaatttgcc cggcacgtag ccgggcaatt ttgcaattaa ctcgccgttt
    25501 caggcttaaa cacaatgtcc tgtttttctt catcttcctc gacgactggc gcagtgctgt
    25561 gaatttcagc aacgcgtttg cgcacaccaa accagcctat aaccagcaga ataccgataa
    25621 tcggcagcgc cgcgatggta taagtcccgt tcgggtaatc gaacgccatc agcaccagga
    25681 cactcagtaa aaacagtaat gtcagccagg aagtgaaggg cgcgccaggc agtttaaaac
    25741 tgacatccgc tgctttgcct tctttaatcg ctttacgcag gcgcatctgg caaacgatga
    25801 taaacgccca tgaagcgatg attcccagcg acgcgaagtt caacacaatc tcaaatacgc
    25861 gtgacggcac cagatagttg aggaatacgc cgacgacata cacaaccagt gtcgccagaa
    25921 tcccggcata cggcacatgc tgacgactca ttttcgccat aaaactcggt gcggaaccgc
    25981 ccatcgccat cgagcgcaga atacgcccgg tgcagtacag acctgaattc aggctggaga
    26041 gggcagcggt cagcaccaca atgttcataa tgctgcctat atatggcaca cccagtttag
    26101 agaaaaacgt cacgaacgga ctttgccccg cctgatatgc gctccacggc aataacataa
    26161 ccagcaacac cacggagccg acgtaaaaca gaccaatacg ccaaatcaca ctgttaatcg
    26221 ctttaggtac catggtctgc ggatctttac attctccggc cgctgtaccc accatttcaa
    26281 tggaggcaaa agcaaacact acgccctgaa tcaacaccag cgcaggcagc aaaccgtggg
    26341 ggaagaagcc gccattatcg gtgattaaat gaaagccagt ggtgttgcca tccagcggct
    26401 gaccgctacc gaggaacact gtacccacga ccaaaaaggt tacaatggcg agcactttaa
    26461 taagcgcaaa ccagaactcc atctccgcaa accatttcac accgatcata ttcatggtgc
    26521 caacgatggt cagtgcagcg agcgcaaaga cccactgcgg cacgccgcca aacgcgcccc
    26581 agtaatgcat atacagagcg acggcggtaa tatcaacaat ccccgtcatc gcccagttga
    26641 tgaagtacat ccagccagca acataagcgg ccttctcacc caaaaactca cgggcataag
    26701 agacaaaact gccactggaa gggcggtgta acaccagctc acccaatgca cgcaaaataa
    26761 aaaacgaaaa caggccgcag atcaaataga ccagtgccag tgcgggcccc gccatttgca
    26821 gtcgcgcccc cgcgcctaaa aacaaacccg taccaatcgc gccgccaatg gcgatcatct
    26881 gtacctggcg attgcccatc gctttgtgat acccctcttc gtgggcatta agccagcggc
    26941 gtttcgcggc gtgttgatct gaagtgtcgg tgttgtgttt actcattgct ctccctgatt
    27001 gctttaatga aaaagtcata taagttgcca tgaacaatgt ttattcatcc tggcgatgac
    27061 aagattcacc attattcttt atgggtataa ctgtcggcgc agaatcctac cttttatcat
    27121 gtaacgatgc aaaataatcc cgctataaat atgtggggat aaagtcggct ggcgacaaaa
    27181 tagcaacctg atgaaattat gacggaaaca accactattg gtttgatgat acctgactgc
    27241 agtcctactc ttgcgccact cgttcgtcgc tctgaacgcc agtggttgca gtggacactg
    27301 gcgtggttgg ctcaatgaat agtgaggggc tagcacatga tgggtttcag gggtaatacg
    27361 ccaaatacca atacaattgc tgattaaatg agccaattgc cgacattaca gaaaaggcta
    27421 aaaaatgtaa gaggcatgta gggtgataaa cgcgctattg cccaacagga gtt
//
LOCUS       DAFGPF010000062        27276 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFGPF010000062 DAFGPF010000000
VERSION     DAFGPF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27276
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.062"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            67..798
                     /gene="artJ"
                     /locus_tag="LSX49_002943"
     CDS             67..798
                     /gene="artJ"
                     /locus_tag="LSX49_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HBL7169329.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGVSATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKINDQWFPQ"
     gene            complement(827..1954)
                     /gene="rlmC"
                     /locus_tag="LSX49_002944"
     CDS             complement(827..1954)
                     /gene="rlmC"
                     /locus_tag="LSX49_002944"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HBL7169330.1"
                     /translation="MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVEEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLQE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIAPEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGEVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGYRIERVQLFDMFPHTAHYEVLTLLVKQ"
     gene            complement(1995..2483)
                     /locus_tag="LSX49_002945"
     CDS             complement(1995..2483)
                     /locus_tag="LSX49_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HBL7169331.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            complement(2543..3388)
                     /gene="potI"
                     /locus_tag="LSX49_002946"
     CDS             complement(2543..3388)
                     /gene="potI"
                     /locus_tag="LSX49_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HBL7169332.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVALSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            complement(3385..4329)
                     /gene="potH"
                     /locus_tag="LSX49_002947"
     CDS             complement(3385..4329)
                     /gene="potH"
                     /locus_tag="LSX49_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HBL7169333.1"
                     /translation="MSTLEPAAQPKPFKLWLSQLQMKHGRKLVIALPYIWLILLFLLP
                     FLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQSLQV
                     AAISTICCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKNNGV
                     LNNFLLWLGIIDQPLTILHTNFAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAALDL
                     GARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFF
                     NNRDWPVASAVAIVMLLLLIMPIMWFHKHQQKSEGEHG"
     gene            complement(4339..5472)
                     /gene="potG"
                     /locus_tag="LSX49_002948"
     CDS             complement(4339..5472)
                     /gene="potG"
                     /locus_tag="LSX49_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HBL7169334.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLYSPGLV
                     HPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            complement(5567..6679)
                     /gene="potF"
                     /locus_tag="LSX49_002949"
     CDS             complement(5567..6679)
                     /gene="potF"
                     /locus_tag="LSX49_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HBL7169335.1"
                     /translation="MIALNKKWLSGLVAGALMAVSVSTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKAATPLVSAEVRDNPG
                     IYPPADVRAKLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            complement(7029..7505)
                     /locus_tag="LSX49_002950"
     CDS             complement(7029..7505)
                     /locus_tag="LSX49_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HBL7169336.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            complement(7593..8495)
                     /gene="rimK"
                     /locus_tag="LSX49_002951"
     CDS             complement(7593..8495)
                     /gene="rimK"
                     /locus_tag="LSX49_002951"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HBL7169337.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            complement(8556..9278)
                     /gene="nfsA"
                     /locus_tag="LSX49_002952"
     CDS             complement(8556..9278)
                     /gene="nfsA"
                     /locus_tag="LSX49_002952"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HBL7169338.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALTAAESLGLGGVYIGGLRNNIEAVTELLKLPQHVLPLFGLCLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKDALAQYDEQLAEYYLTRGSNNRRDTWSDHIRR
                     TIIKESRPFILDYLHKQGWATR"
     gene            complement(9262..9549)
                     /locus_tag="LSX49_002953"
     CDS             complement(9262..9549)
                     /locus_tag="LSX49_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1418 family protein"
                     /protein_id="HBL7169339.1"
                     /translation="MRAIGKLPKSVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNHPPQYSRSEREKDNDANH"
     gene            9709..9966
                     /gene="grxA"
                     /locus_tag="LSX49_002954"
     CDS             9709..9966
                     /gene="grxA"
                     /locus_tag="LSX49_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HBL7169340.1"
                     /translation="MQTVIFGRPGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            complement(9996..10373)
                     /locus_tag="LSX49_002955"
     CDS             complement(9996..10373)
                     /locus_tag="LSX49_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HBL7169341.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSHRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            10642..12327
                     /locus_tag="LSX49_002956"
     CDS             10642..12327
                     /locus_tag="LSX49_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HBL7169342.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            complement(12503..13039)
                     /gene="rcdA"
                     /locus_tag="LSX49_002957"
     CDS             complement(12503..13039)
                     /gene="rcdA"
                     /locus_tag="LSX49_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RcdA"
                     /protein_id="HBL7169343.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSRFTEIMSRQYQAFFSDVSDAPGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERIAG"
     gene            13123..14331
                     /locus_tag="LSX49_002958"
     CDS             13123..14331
                     /locus_tag="LSX49_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169344.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALIGMMVLSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATMHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMMVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            14331..15146
                     /gene="ybjI"
                     /locus_tag="LSX49_002959"
     CDS             14331..15146
                     /gene="ybjI"
                     /locus_tag="LSX49_002959"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415365.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HBL7169345.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFTTVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVPVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGSAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFKQ"
     gene            15232..15516
                     /locus_tag="LSX49_002960"
     CDS             15232..15516
                     /locus_tag="LSX49_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169346.1"
                     /translation="MIMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(15557..16789)
                     /gene="mdfA"
                     /locus_tag="LSX49_002961"
     CDS             complement(15557..16789)
                     /gene="mdfA"
                     /locus_tag="LSX49_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HBL7169347.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     SLMVIFLKDKQMGNSHEG"
     gene            17074..17670
                     /gene="ybjG"
                     /locus_tag="LSX49_002962"
     CDS             17074..17670
                     /gene="ybjG"
                     /locus_tag="LSX49_002962"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL7169348.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAAV
                     LWLWGLTAQRQLVIKIAIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRFCFALPIRKGWVRD"
     gene            17728..18486
                     /gene="deoR"
                     /locus_tag="LSX49_002963"
     CDS             17728..18486
                     /gene="deoR"
                     /locus_tag="LSX49_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HBL7169349.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHISKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY"
     gene            complement(18533..19735)
                     /gene="dacC"
                     /locus_tag="LSX49_002964"
     CDS             complement(18533..19735)
                     /gene="dacC"
                     /locus_tag="LSX49_002964"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HBL7169350.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRMWDFVMMKFH
                     QWFGSWFS"
     gene            19982..20608
                     /gene="gstB"
                     /locus_tag="LSX49_002965"
     CDS             19982..20608
                     /gene="gstB"
                     /locus_tag="LSX49_002965"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase GstB"
                     /protein_id="HBL7169351.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDTDF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIAPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            complement(20605..21720)
                     /gene="yliI"
                     /locus_tag="LSX49_002966"
     CDS             complement(20605..21720)
                     /gene="yliI"
                     /locus_tag="LSX49_002966"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose sugar dehydrogenase YliI"
                     /protein_id="HBL7169352.1"
                     /translation="MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLP
                     DNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYL
                     FIALGENNQRPTAQDLDKLQGKLVRLTDLGEIPDDNPFIKESGVRAEIWSYGIRNPQG
                     MAMNPWSNALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(21831..22214)
                     /gene="bssR"
                     /locus_tag="LSX49_002967"
     CDS             complement(21831..22214)
                     /gene="bssR"
                     /locus_tag="LSX49_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HBL7169353.1"
                     /translation="MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            22427..23752
                     /gene="rimO"
                     /locus_tag="LSX49_002968"
     CDS             22427..23752
                     /gene="rimO"
                     /locus_tag="LSX49_002968"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBL7169354.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            complement(23799..25127)
                     /locus_tag="LSX49_002969"
     CDS             complement(23799..25127)
                     /locus_tag="LSX49_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBL7169355.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYGLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSVSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKSVTGDEYNAKNAIFTVSEAMEHFSYLPTGLYVF
                     AYKKDVYFQVCTLIIFFAALVAVISGASCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECTTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(25135..27230)
                     /locus_tag="LSX49_002970"
                     /pseudo
     CDS             complement(25135..27230)
                     /locus_tag="LSX49_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601258.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE9 sensor domain-containing protein"
BASE COUNT         7002 a         7038 c         6476 g         6760 t
ORIGIN      
        1 tggcattgtt atcccatgcc gcagacacgg ccaaaaatca taagattgac agacgggagt
       61 tccatcatga aaaagttagt tcttgccgct ttacttgctt cttttacttt cggtgcttct
      121 gccgcagaga aaatcaattt tggcgtttca gccacctatc caccctttga atctataggt
      181 gctaataatg agattgtcgg ctttgatatc gacctggcaa aagccttgtg caaacaaatg
      241 caggcagaat gtacttttac taatcacgct ttcgacagcc tgatcccgtc actgaaattc
      301 agaaaatatg acgccgtaat ctccggaatg gatatcacgc cggagcgtag caaacaggta
      361 tcgtttacca cgccctacta cgaaaactca gccgtcgtga ttgccaaaaa agatacctac
      421 aaaacgtttg ccgatctgaa aggcaaacgt attgggatgg aaaacggcac cacgcaccag
      481 aaatatattc aggatcagca cccggaagtg aaaactgtct cctatgacag ttatcagaat
      541 gcctttatcg atctgaaaaa tggccgtatt gatggcgtat ttggtgacac cgcagtggta
      601 aacgaatggc tgaaaaccaa tccgcaactg ggcgttgcta ctgaaaaagt gaccgatccg
      661 caatacttcg gcaccggcct gggtatcgct gtacgtccgg ataacaaagc tctgctggaa
      721 aaactgaata acgcgctggc agcaattaaa gctgacggta catatcagaa aatcaatgac
      781 cagtggttcc cacagtaaga ttcagaaagc cgcacctgcg gcttttttat tgcttcacca
      841 gtagcgtcag cacttcatag tgcgcggtgt gcgggaacat atcaaaaagc tgtacccgtt
      901 cgatgcgata accaggcagt tcgcggatat ctttcgccat agtttgggcg ttacagctgg
      961 agtagataat aaaacgcggt gccatcgttg agagataatc acacagcggt ttaccgatgc
     1021 cgcggcgcgg cgggttaacc agcaccagct ccggcacttc cccctgagcg gtggcaaact
     1081 gcgtagagtc cagcgcctga aattgcaaac gcgttaagcc cagttcagcg gctgactgct
     1141 tcgcacaggc aatggcctct ggtgcaattt cgatcccggt taactgcatg tcaggcgtcg
     1201 cgcagtgtaa accaaagcca cccacaccgc agaacagatc ccacatatgt ttaaccggca
     1261 gctgtcgtac ccagtcgcgc gcggtggcgt acagctggct ggcgaccgcc ggattagtct
     1321 ggaagaaact ttgcggacgg atccacagcg gtacgtcatt aaaacgctct gccagtgcct
     1381 gttgttcggt caggtagatc tccgtctccc cttccataat cgccatatgt accggctgaa
     1441 tattgacggt aataactttc agctgcggta attgttcctg taaccacggc agcgccttac
     1501 gcaattgcgc cagtttggta tcagaacgca gtacaaaacg cagcatcatg ccaccatcgc
     1561 tctggctttc agtcagcaga atgtatttca gttcaccacg tttacgcgcc acgttgtagg
     1621 gcgttaaccc cgcacgggcg ataaacggtt ttagcgccgc aaaaacgggc gcaaatgagg
     1681 ctggataaag cgggcagtca caaaggtctt ccggtgtacc atctcgatgc agcataccga
     1741 gcagtggttt ttcaacgcta ccactcacca ccattttggc tttattacga aacccttgtt
     1801 ccgggcctga caccggcgca caccattcct caaccggaaa atcggcgagc agatttttaa
     1861 gatcggcagt tttagcggag agttgctctg gaatcggctg cgttatccac tgacaggaac
     1921 gacagcgacc cgcgtcgtaa agtgcgcact gcatacattg accttcacat catcaggggc
     1981 gacgattata cacattattg caactggaag aaccgccgac tggtcgaggg aacgaacagc
     2041 agcatcagga tgagcatatc cggcagcttc tgcagcatca ggctatggaa gatttcacgt
     2101 tttgattcac cgggaatgct gaacagctcc ggataaccat accccagcga agccgcccac
     2161 aagtaacttg cggctgtgat ttgtgtcaac agatacagcc agcgcgccca gcgacgccct
     2221 ttcaccagtg aaaacgcaca ccagatctca atgaaaacca gcaccagact gctcaaaaag
     2281 accagcgtta aactccaggt ttgtacgctg cgatgaatga actcgccaat accgcgcacg
     2341 cccagcgtat tgaaaatcat cagcacgtcg aggccacgga tcataataat ggcgagcgcc
     2401 gccacctgca ccagcgcagg cacattcagg cgagcatgag atgaagatgt tttcttaaaa
     2461 aatcccaacg tttcgtcttc catgaaaaca atgccgcgac atgcgcggca ttatgtagcc
     2521 aggttggcaa attttagtgt cttcagccac gtcttgcacg ctggatgtcg cgtatccgct
     2581 gtttttctgc gcgcgccatc agataccagg cgataaatcc gacaattccg accgcgccga
     2641 ggatcaatgt tgccagggcg ttgatttccg gattcacccc catccgcacg ctggaaaaga
     2701 ccagcatcgg taatgtggtg gctcccggcc cggaaacaaa gctggcgatc accagatcat
     2761 caagcgacaa agtaaaagcc agtaaccagc cagaaatgat cgcgggcatg atcatcggta
     2821 gcgtaatgac aaaaaacact ttcagcggcg tcgcaccgag atccatcgcg gcttcttcta
     2881 tcgagcgatc cagttcccgc agacgcgacg aaataacgac tgccacataa gccgtacaga
     2941 aagtgacatg cgccagccag atggtgagca taccgcggtc cgcaggccag ccaatagcat
     3001 gagcaagcgc gacgaataac aacaacagcg acaaacccgt gatgacatct ggcattacca
     3061 gcggtgcggt gatcatgaag gcaaaaccat ttgatccgcg aaacctgcca aagcgcacca
     3121 gcacgaccgc cgcaatagtc ccgaggatcg ccgccgccgt cgccgcacag gccgcaattg
     3181 tcagacttaa agcaaccgca ctcatcatcg cgtcatcgcg caataattcg ccataccagc
     3241 gcgttgacca gccggcccac accgtcacta gcttcgagct gttaaacgaa tagataacaa
     3301 gcatcagcat tggcgcgtag agaaaggtga agcccaacag caaaatcaca atccgccagg
     3361 gcgaacgaac caccggtaaa ttattcatcc gtgttctccc tcgctttttt gctgatgttt
     3421 gtggaaccac attatcggca taattagcag cagcaacatg acgatcgcta ccgctgaggc
     3481 caccggccag tcgcggttgt taaagaactc ctgccacagc acgcgcccga tcatgatgct
     3541 gtccgggcca ccgagcagtt ccgggatcac aaactcgccc acagccggga taaacaccag
     3601 catcgatccg gcaataatcc cacctttagt cagcggcacg atcacagtaa agaacgtttt
     3661 cagcggtcgt gcaccgagat ccagtgccgc ttctaccagc gaataatcaa tacgaatcaa
     3721 cgcggtgtaa atcggcagca ccataaacgg cacgtaggcg taaacaatgc caatataaac
     3781 cgcaaagttg gtatgcagaa tggtcagcgg ttgatcgata atccccagcc acagcagaaa
     3841 attattcagc acaccgttgt tttttaatat tcccatccag gcgtagacac gaatcagaaa
     3901 cgaggtccac gacggcagga tcaccagtag taataagata ttacgggtcg aaggcttact
     3961 gtgcgccacc gcccacgcca gcggatagcc gatcagtaaa cagcaaatag tcgaaatcgc
     4021 cgccacctgt aacgactgga gataagcatc aaaatagagc ggatcgtcgg tcagttgcag
     4081 aaaattaccg agattaagag tgatagaaag ttgcccgtca gcccactcca tcaattcggt
     4141 ataaggtgga atagcgcgcg ccatctccgc caggcttatt ttaaagacga tcagaaatgg
     4201 cagcagaaac agcaagatca accagatata cggcaacgca ataaccagtt tgcgcccatg
     4261 tttcatttgc agctgcgaca accacagctt aaagggtttt ggctgggcag caggttcaag
     4321 tgtactcatc tttgctcctt aaaccgtcag caccacacag ctgtccactt cccagcacaa
     4381 acgcacttcg tcgccccagg tcggtaaccc tttacgatga cgatgggcgt tttgtagctg
     4441 ggcgctaatc atctgcccac ttttcagacg aacgtgatac accgaaagat cgccgagata
     4501 ggcaatgtgt atcacctccc ccaccgcgaa gttacaacca ttggcgggcg gttcctcgca
     4561 aagcatgatt ttttccgggc gaagcgccac atgcaccggc acgttatcga ccactgaagc
     4621 atccgcatcg actttcagtg gatgcaccag ccccggcgaa taaagcacca gaccatcttc
     4681 ctgacgctct ttgagtacac cttcaaagac attaaccgaa ccgataaatt cagcactgta
     4741 gcgagtggtc ggatgctcgt agatctcttc cggctcgcca atctggacaa atttcccacg
     4801 attcataatg gcgatgcgcc ccgccatagt catcgcctct tcctgatcgt gagtaaccat
     4861 tacgcaggtc acaccgacgc gctccagaat atccaccact tcaagctgca tccggtcacg
     4921 cagcttttta tccagcgcgc ccatcggctc atcgagcagt aatagtttcg ggcgcttggc
     4981 aaggcttctg gccagggcca cacgctgacg ctgaccacca gaaagctgat gcggtttgcg
     5041 tttggcgaac tcctgcatat gcaccagccc aagcatctca ttgacccggc tggcaatttc
     5101 cgctttcggt agtttgtcct gtttcaggcc aaaagcgatg ttctgttcca cggtcatatg
     5161 cggaaacagc gcgtaagact gaaacatcat attgatgggg cgcaggtaag gcggcacctg
     5221 tgacaaatcg acgccatcga gcataatctg cccggccgaa ggttgttcaa aacctgccag
     5281 catacgcagc agcgtggact tgccacagcc ggatgcgccc agcagcgcga agatttcacc
     5341 tttgtagatg gtcaggctga catcatccac cgcatgttga ccatcgtagg atttggtcag
     5401 gttacggatt tctaatagcg gcgtcagcgc cttacgggtt ttcgcctgcg ggcgagggat
     5461 agcgtcattc acggctgctc tccggcattg aatgtgtgca agcgcaccat gatggtgcga
     5521 attgccggcg ggtgtggtgc gcccctccgg catctacggc tgcggattat tttccgctct
     5581 tcactttggt ccaggcgcgg gtgcgcacac ggtcgatttt cgggtcctgc actttcagag
     5641 tgaacagctt cgcacgaaca tccgcaggcg gataaatacc cgggttatca cggacttccg
     5701 cactcaccag cggcgtggct gctttattgg cgttagcata gaacacatgg tcagagatat
     5761 gtgccaccac atcaggacgc agcaggtaat tcaggaactg ataggcttcg tctttgtttt
     5821 tggcatccgc aggcatggcg aatacatcaa agaacgccat cgccccttct tttggaatcg
     5881 agaacgagac attcacgcca ttcttcgctt ccttcgcgcg gtttgacgcc tgccagacat
     5941 cgcccgccca gccaatagcg acacagatgt caccattcgc cagatcattg atgtattggg
     6001 atgaatggaa ataacgaatg ttcgggcgca gctttaacag cagatcggta gccggtccgg
     6061 tgtaatcatc cgctttagtg ctgttaggat ctttgccgag ataattcagc acggtagcaa
     6121 acacttcttc tggcgcatcc aggaaagaga caccgcagct tttcagtttt tccagatttt
     6181 caggtttgag gatcaagtcc cagctatcga cgggcgcgtt ttcgcccagc accgctttaa
     6241 ctttatcgac gttatagcca atcccggtcg tcgcccacat atagggcata gcaaatttat
     6301 tgtcgggatc gtgtttggcg accaacttca gcagctccgg atcgagattc ttccactccg
     6361 gcaatttgct tttatccagc ggctggaaaa ctcccgctgt cagctggcgc tcaagaaagc
     6421 ttgctgacgg caccaccaga tcaaagccgg tgctccccgc cattaatttg ccttccagta
     6481 cttcgttaga atcgaaaaca tcatagacga ctttaatacc ggtttctttt tcaaagttgg
     6541 ccaccgtgtc cggggcgata taatcagacc agttataaat gtggagtgtt ttttgttcag
     6601 ccgcgagcgt gctgacagaa acggccatca gagcacccgc aaccagaccc gatagccatt
     6661 ttttatttaa ggcgatcata tctctttcct tctgaaaatt cgttaacaaa cgaacaaaag
     6721 ttgtcacact gaaagatatg caataaacgt gcatattttt atcggcgcgg tgtaagaaaa
     6781 gagaactctc tcccggcctg cactgctcac tatataaaag catcgcaaga ataactttag
     6841 ccagggtttg agactatagc tcggattaaa aaacggtatt taacaaattt ttatgcgtat
     6901 ttgctctatg tgataaagcc aaatcggcac aagagaagtg aattaatctt taataaaagg
     6961 ttaaaatcag cggataattt tgcggcacgc agtcactgcg gcagcgactg cgtgctcgaa
     7021 agaagttatc agtggaggaa atagttttcg gtaacgttat tttgcccttc atcgtcagtc
     7081 ggtaacagca gttgatgggc attagcttca agaatgacca tcgaaatctg ctcttcgctc
     7141 tgacgcacga accatgcaaa ctgctcatag gttacgccct gcataacgga taaagactgg
     7201 caaaccacca gctttggcag attatcatcc tgcatatcaa gaaatgcttt cacggtcagc
     7261 gaactggcat tgatggctga taaatccgcc gccagcggca atacggctga aggtcggact
     7321 tccgccatgg cagaaaacag gatcgtgtta tcgatcagat cgattttagc atcaaagaca
     7381 ccgtcgaaat tctgcatatg gggcagatgc agagcctgac agttatcaca ttcaaaaaaa
     7441 ctcatcccca ggtcatcgag ccattgacgc aacgtatcca gaccaggaac gaccagcgat
     7501 gtcataattt tgtacaacct cttccgataa aaagaccggc acagcttacg caaaaagcgc
     7561 aggcaaaacc atgatcagta atgtgattgc gactaaccac ccgttttcag gcaatattct
     7621 gtcgtagcgt ggcgttcgat ccagcggatc attttacccg cgatgtcgat accggtggtt
     7681 ttttctattc cttccagccc tggcgacgca ttcacttcca tcaccaacgg cccgcgatta
     7741 gcacgcagaa tatccacacc agcaacgtcc agcgccatcg ttcgcgcggc ttttatcgcg
     7801 atttcacgct cctgtggtgt gatactggcg acgcttgccg cgccgccacg atgcaaattg
     7861 gaacgaaaat cgccctcttt cgcccgccgt tcaatcgcag cgactacttc atcgccaaca
     7921 accagacagc ggatatcgca cccttgcgcc tctttgatat attcctgcac cagaatatgc
     7981 gcgttcagac cgcggaaagc gtcaatcacg ctttccgccg cctgacgcgt ctccgccagc
     8041 acgacgccaa ttccctgcgt gccttcaacc agcttgacca ccagcggcgc accaccgacc
     8101 atgtcgatta aatcgctggt atcatccggc gaatgcgcaa tgcccgtgac aggcaggtcg
     8161 atgccctgac gcgccagcag ttgcatggaa cgcaatttgt cacgcgcccg ggcaatggcg
     8221 accgactcat tgagcggata gctccccagc atctcgaact ggcgcagtgc cgccgtccca
     8281 taaaaggtaa tggcggtgcc aatacgcggg atcactgcgt caaaatgggg taacttgcgg
     8341 cctttgtagt gaatagaaga cgccgcagga tttatgttca tatagcaaga aagcggatca
     8401 agaatttcaa ccaggtgacc gcgctgtata gcggcttcac gcagccgctt acacgaatag
     8461 agcgttccat cccgggacaa tatggcaatt ttcaccctgc acctctctgt cagacctggt
     8521 caaaagcccg cgtatcatac atcgacgtgg cagttttagc gcgtcgccca accctgtttg
     8581 tgcaaataat ccagaataaa tgggcggctt tctttaatga ttgttcggcg gatatgatcg
     8641 ctccaggtat cccggcgatt attgctgcca cgggtgaggt aatattccgc cagttgctcg
     8701 tcatactgcg ccagtgcgtc tttatccagc ggttgatagc tgttttcatg caccaaaatg
     8761 gaggccggta aacgcggctt aagatccgga ttatccgcag gccagccaag gcacagccca
     8821 aacagcggca gaacatgctg cggtaatttc agcagttccg tcaccgcttc aatattattg
     8881 cgcaggccgc cgatatatac cccgcccaat cccagcgatt ccgctgcggt taatgcattc
     8941 tgcgccatca ttgccgtatc aacgacaccg agcaacagtt gttccgccag gccgagctga
     9001 gcatccggac agatctgtaa atggcggtta aagtcggcac agaacaccca aaactctgcc
     9061 gcttgcgcta cgtgtttttg cccgccggtc agcgtcacca gttcttcacg taacgctttg
     9121 tcggtaatgc ggataatgct actgcactgc aaaaaactgg aactggacgt cgcacgggcg
     9181 ctgttaataa tcgcctcacg ctgcgcttcg gaaatgggtt catcagtgaa atggcgaatg
     9241 gagcgatggc cacaaataag ttcaatggtt ggcgtcatta tctttttctc tttctgaacg
     9301 tgaatattgc ggtggatggt tcatcagctg tggggcaaga cgttttgcca cctgaagaat
     9361 aaccaccacc gcagcgggaa gcatgagcaa aacaccgaga aaaatcatca gaatctgcac
     9421 ttctggccga gaaaatggct caggtagcga cagggagtcg cttaccgaca gcagcgccac
     9481 cgccagcaac atcattccga taaattccag tatcaacacg cttttaggca atttaccgat
     9541 cgcgcgcata cgcttccctc tgcaaagtga gccttcagtc taaaactttt cactgtattg
     9601 tgtttaacag ttatagcttt tagcaattaa tgcaacaggt taaacctact ttcagcgaat
     9661 acattttagc gtgatcatta caggcataaa tctatgagga gagaaataat gcaaaccgtt
     9721 atttttggtc gtccgggttg cccttactgt gtgcgtgcaa aagatctggc tgagaaattg
     9781 agcaatgaac gcgatgattt ccagtatcag tatgtagata ttcgtgcgga agggatcact
     9841 aaagaagatc tacaacaaaa ggcaggtaaa cccgtagaaa ccgtgccgca gatttttgtc
     9901 gatcagcaac atatcggcgg ctataccgat tttgctgcat gggtgaaaga gaatctggac
     9961 gcctgatcgt ctgacaagcc ctcgcattga gggctttatt gattttttct gtgctgtggt
    10021 ttaaacaaac tactgataaa taagaaacac aatgccccca gcgcacacca gaacaccgca
    10081 cttaataacc atgccagctc ttgccagaat gagcgcgtcg gtgaaaaaaa cagccgcata
    10141 atgagcatcg agcagggtgc cgccagcatt gcgccaaaca gaggtttcag gacttctcta
    10201 cgatgtgaaa agaagctggc aactgcacca ggaagaatga aaaatagcaa accgatttca
    10261 ggatgcccgg cagcccgaaa agcgcctttc atgtgcgtcg ccagaaaaag acacaccaca
    10321 atgaagagga caaaacagca gattgccccc gcccaacgtt gtttatgttt cactcgttcc
    10381 tcctgacact gcgtctatcg aacacatttt tcgccagtgt ggcgttcagt aagataaagc
    10441 cgcttcgcat tccatgctaa tataggccaa cgcaattcat atagccgttg atacctaatg
    10501 tgattacact agtaaaatat attgttactt tactatcgtt taggtgcgct gaatgaatct
    10561 gcgccctgaa ttctggtaaa aacattatcg taaattacca tttctttcaa cagcttacta
    10621 gtaaacaaga agttagcctc cgtgaatata aacgtcgccg aattgttaaa tgggaattac
    10681 attctgttat tatttgtggt cctcgcgctt gggctatgtc tcgggaaatt acgacttggt
    10741 tcgatccaac tgggtaattc cattggcgtt ttagtcgtat cgctgttatt aggccaacaa
    10801 catttcagca ttaacaccga cgcgcttaat cttggcttta tgctgtttat tttctgcgtc
    10861 ggggtcgaag ccggaccgaa ctttttttcc attttttttc gcgatgggaa aaattaccta
    10921 atgttagcac tggtgatggt tggcagtgcg ctggtgatcg ccttagggtt aggtaagctg
    10981 tttggctggg atattggcct gacggccggt atgttagctg gctctatgac gtcgacaccg
    11041 gttctggtcg gtgctggcga tacactgcgt cattccggca tggaaagcag gcagctctca
    11101 ctggcactgg ataatctgag cctcgggtat gccttaacct atttaatcgg tctggtgagt
    11161 ttgattgttg gtgcgcgtta cttgccgaaa ttgcagcatc aggacttaca gaccagcgcc
    11221 cagcaaatcg cccgcgaacg tggcctggac actgatgcca accgtaaggt ttatttaccg
    11281 gtgatccgcg cctaccgcgt cggcccggag ctggtggcct ggaccgacgg caaaaatctg
    11341 cgtgaactgg gtatttatcg acaaactggc tgctacattg aacgtattcg acgtaacggg
    11401 attctggcaa atccagacgg tgatgcggtg ctacaaatgg gcgatgaaat agcgttggta
    11461 ggctatcccg acgcccacgc ccgactcgat cccagcttcc gtaacggcaa agaagttttc
    11521 gatcgtgacc ttctcgacat gcgtatcgtc actgaagaag tggtcgttaa aaaccataac
    11581 gccgttggca aacgtctcgc acaactgaag ttgaccgatc acggttgctt ccttaaccgc
    11641 gtcattcgta gccagattga gatgccgata gatgacaacg tcgtgcttaa caaaggtgac
    11701 gttttacaag tcagcggcga tgcccgtcgc gtaaaaacca tcgccgatcg catcggcttt
    11761 atctcgattc atagccaggt cactgacttg ctggcattct gcgccttctt tgttattggg
    11821 ctgatgatcg ggatgatcac cttccagttc agcacattca gtttcggcat gggaaacgct
    11881 gccgggttgt tattcgccgg aattatgctg ggatttatgc gcgctaacca cccgaccttc
    11941 ggttacattc cgcagggtgc attaagcatg gtgaaagagt tcggcttaat ggtgtttatg
    12001 gcaggcgttg gtctgagcgc cggtagcggt attaataacg gcctgggcgc gattggcggt
    12061 cagatgttga ttgccggatt gattgtcagt cttgtgccag tggttatctg tttcttgttc
    12121 ggtgcttatg tattgcgaat gaaccgcgca ctgttgttcg gcgcaatgat gggcgcacgc
    12181 acctgcgcgc cggcaatgga gatcatcagt gatacagctc gcagtaacat cccggcgctg
    12241 ggctatgcgg gcacctatgc aatcgccaac gtcctgctga cgctggcagg gacaatcatc
    12301 gtcatggtat ggccaggatt aggataaaac tgaagttgcc ctgaaaatga aatttttttt
    12361 gcacaaccgc agaacttttc cgcagggcat cagtcttaat tagtgccact gcttttcttt
    12421 gatgtcccca ttttgtggag cccatcaacc ccgccatttc ggttcaaggt tgatgggttt
    12481 tttgttgcct gaaatttatc tactacccag caatcctctc aaccatcctc aaaatctcct
    12541 cgcgtgatag cggcttacgg tcggtgacaa aatgcagcgt cattccctca ataaacgcat
    12601 caagcgcgcg ggcggttccg ggttcaaacc attgttcgag cgtttgttga ctgcgctgca
    12661 tccagttttg cattaccgtt tttaagagcg gttttcggct agccagcgcg tagagctggt
    12721 acatcagctc catattatcc ggcgttgcga cctgtgagct gtagatcata tcggtgatag
    12781 cctggcatgc gcctggagca tcactaacat cgctaaaaaa tgcctgatat tgccgggaca
    12841 tgatctcagt aaaacggctg aacgcctcca gcaacaactc atcaattcct gaaaaatagt
    12901 aggtcatcga tcccaacggc accccggcaa gggtagcaat tttgcggtgt gtaacagcat
    12961 gtattccgta aagtttcacc gcctccagcg tggcctggat aattttttct cgtcgttgcg
    13021 gatcgttagc gcgacgcatg tcatttcctc tctctgcaat tgtgtacaaa tgtacacagt
    13081 cttgctaatg ttgtcttccc tcttcttatt ttgacgtggt ctatgaccgt aaattcttca
    13141 cgtaatgcat tgaaacgccg aacctgggcg ctgtttatgt tcttcttttt gccaggcctg
    13201 ttaatggcgt cctgggcaac ccgtacgcct gctatccgcg atattctctc tgtctcgatc
    13261 gctgaaatgg gcggtgttct ctttggtctg tcgatcggtt cgatgagcgg tattctctgc
    13321 tcggcgtggt tagtgaaacg ctttgggacg cgtaatgtca tccttgtcac gatgtcctgc
    13381 gcattgatcg ggatgatggt attaagtctg gcactctggc tgacatcgcc cttgctcttt
    13441 gccgttggtc tcggcgtctt tggggctagt tttggttctg cggaagtggc gataaacgtt
    13501 gaaggtgccg ccgttgagag agaaatgaat aagacggttt taccgatgat gcacggtttt
    13561 tatagcctgg gcacgctggc aggcgctggt gtcgggatgg cactgacggc ctttggcgtt
    13621 ccggcaacga tgcacatttt attggcggcg ctggtaggca tcgcgcctat ttatatcgcc
    13681 attcaggcaa tccctgatgg tacgggcaaa aatgctgccg atggcaccca gcatggcgaa
    13741 aaaggcgttc ctttttatcg cgatatccag ttgctgttga ttggtgttgt agtgctggcg
    13801 atggcctttg ccgaaggttc tgccaacgac tggttaccct tattaatggt tgatggtcac
    13861 ggttttagcc ctacttccgg ctcgctgatt tatgccggtt ttactctggg gatgaccgtt
    13921 ggacgcttta ccggcggttg gttcattgac cgttacagtc gcgttgccgt ggttcgggcc
    13981 agtgcactaa tgggggcgtt gggtattggg ctgattattt ttgtcgatag cgcctgggtc
    14041 gctggggtgt ctgttgtact ttggggactg ggtgcctcgc tgggcttccc gctgaccatt
    14101 tctgccgcca gcgataccgg ccccgatgca ccaacccgcg tcagcgtggt agctacgacc
    14161 ggttatctgg ctttcctcgt cgggccgccg ctgctgggct atctcggcga acattatgga
    14221 ttacgtagtg caatgatggt tgtactggcg ctggttattc tcgcggctat tgtcgcgaaa
    14281 gccgtcgcca aacccgatac caaaacgcag acggcgatgg agaatagttg atgagcatta
    14341 aattaattgc ggtagacatg gatggtactt tcttaagcga tcaaaaaacc tataaccgtg
    14401 agcggtttat ggctcagtat cagcaaatga aagcacaagg cattcgcttt gtggtcgcca
    14461 gcgggaatca atattatcag ttgatctctt tctttcctga aattgctaat gaaattgcct
    14521 ttgtggctga aaacggcggc tgggtagtga gcgaaggcaa agatgttttt aatggcgagc
    14581 tgtcgaagga tgcgtttact actgtcgtgg aacatttgct gacgcgcccg gaagtggaaa
    14641 ttattgcctg cggaaaaaat agcgcctata ccctcaaaaa atatgacgat gccatgaaaa
    14701 cggtggcgga aatgtattat caccgtctgg aatacgtcga taactttgac aacttagaag
    14761 atatcttctt taaatttggc cttaatctct ctgacgaact gatcccacaa gtgcaaaaag
    14821 cattacatga ggccatcggc gatatcatgg taccggtcca taccggcaac ggcagcatcg
    14881 atctgattat ccccggtgta cataaagcca atggccttcg ccaactgcag aaattatggg
    14941 gaatagacga cagcgaagtg gtggtctttg gcgatggcgg taacgatatt gagatgctgc
    15001 gtcaggcagg gtttagcttt gcaatggaaa atgccggcag cgcggtcgtc gcagcggcaa
    15061 aataccgggc aggctccaat aaccgtgaag gcgtactgga tgtgatcgat aaagtgctta
    15121 aacacgaagc gccatttaag caataaaaaa ggcagcacgc ccggcaacac aatacctgaa
    15181 tgaaggctgc ataattcgcg gaaattaacc cgctgcatta tttcaggcga aatgattatg
    15241 aaaaattgtc tactgttggg cgcgctttta atgggcttta ctggtgtggc gatggcgcaa
    15301 agtgtcaccg tcgatgtgcc gagtggatac aaagtggttg tggttcctga ttcagtcagc
    15361 gttccacaag cggtcagcgt cgcgactgtg ccgcaaaccg tctatgtggc tcctgcgcca
    15421 gctccggctt accgcccgca tccttatgtt cgccatcttg ccagcgtagg tgaagggatg
    15481 gttatcgaac accagattga cgaccatcac cattaattcg acaatgcctg atcgcacaaa
    15541 gcaatcaggc atttttttac ccttcgtgcg aatttcccat ctgtttatct tttaaaaaga
    15601 taaccatcag cgacagccac aaaatgccgt tgacaaggtt gaagagatta aacagtccgt
    15661 tgcccccgtt cagccaggca tgtttgctga tttcaatacc gacggtaaag atcagcattt
    15721 gcagcatccc catcgccgca gaaaccgtac ctttactcat atcgctggca aacagggtta
    15781 atcgcaccag tcccgcattc gccagaccaa taccgaaagc ataaatactt aacccggcgg
    15841 tcatccataa atacgcgtgc gatgagataa ccgttgccgc agcagcgacc aacagaccaa
    15901 tcataatcgg ccagccgccc ataataatca gcgaacgtac ggtgcggcgc gaggtcagac
    15961 gcgctaacag caagttaccc gcaattaacg ccccaaaaat aggcacttgc agcaggccat
    16021 attcatagct gctcaactgc tcaccggtaa taatgataat cggcgactgg gcgatccacg
    16081 ccagcaacgg caggctaacg aatcccagcg ccagcgcccc cgccacaaag cgaccgttct
    16141 tcagcaccag cttatagtca cgaccgagtt ctttcagcga cagtttctcg cctatacgcg
    16201 tggcggtttc aggcatagct cgttgcagac cgaaaaagga gatcgctgcc aatgcggcaa
    16261 acaagacaaa catcccttcc cagggcagca catggatcca cgccgcgccc accagcggac
    16321 caagtagtgg agcaatcagc gccacgttcg ccattagcgc ggtgatcttg atacaaaccg
    16381 cctcttcgaa ggattcctga attgcggcgt atcccacagc gccaatgaaa cagaggctta
    16441 taccctgcaa gaagcgcaac agggtgaatt gttcaatgtt ttgtgccagt aatattgcca
    16501 gacaggtgac gataaaccac accactcccg ccagcatcac cggacggcgg ccaatacgat
    16561 ccgacaacgg ccccaggagc cattgtaaaa acatcccgcc cgccagatac gcagtcatcg
    16621 aagtaggaac ccaatcaatg cccgcctgat attgttccac cacggccaac ataccgggtt
    16681 gaatcatatc gttgccgata taggttgaaa attcgtaaag caccagacag agagggaaaa
    16741 gtaacgcctg acgtccaagc ctggcaccgg aagctaattt attttgcatg caatttcttc
    16801 gccaataata atcgcgcaaa gtttaataaa agcgcagcta acgagaaagc gaattttgta
    16861 gctgaaacca cggttaagca cattcttaca ttattgcgag tatagctacg ctttctttaa
    16921 gttttattta acctttgccc gttacaatca cctaccgtaa acaggccgct tgagggaaat
    16981 aagacgatgc cgctttaccc agtttaacct gcactttatt ctcaacgact tgcctgtatt
    17041 ggctcccttt taatcacttt gcgtcgggaa gttatgctgg aaaatttgaa tctctctcta
    17101 ttctctctta ttaacgcaac gccagactct gcgccgtgga tgatctcgtt ggcgattttt
    17161 attgctaaag atttgattac cgtggtgccg ttgctggccg cagtactttg gttgtggggg
    17221 cttacagcac aacggcaact ggtgataaaa atcgctatcg cgctggcggt cagcctgttt
    17281 gtgtcctgga cgatgggaca tctttttccg cacgaccgac cctttgtcga aaatatcggc
    17341 tataacttcc tgcatcatgc ggcggatgac tcattcccga gcgatcacgg tacggtgatt
    17401 ttcacctttg cactggcatt tttatgctgg catcgcctgt ggtccggctc acttttaatg
    17461 gtgctggccg tcgtcattgc ctggtcgcgc gtttatcttg gcgtccactg gccgctggat
    17521 atgctcggtg gattgctggc aggtatgatt ggctgcctta gcgcccagat tatctggcaa
    17581 gcgatggggc ataaactcta tcaacgtctg caatcgtggt atcgcttctg ttttgcatta
    17641 ccgatccgca aaggctgggt gcgtgactga tctctgctaa aaagtgtagt attgagcggc
    17701 tcgcttcaat aactattcag agggattatg gaaacacgtc gcgaagagcg tatcgggcag
    17761 ctgctgcaag aattaaaacg cagcgataag ttacatctta aagacgccgc cgccctgctt
    17821 ggggtttcgg agatgacgat tcgtcgcgat ctgaacaacc acagtgcgcc cgtcgttttg
    17881 ctcggcggct atattgttct ggaaccacgc agcgccagcc attacctgtt aagcgatcaa
    17941 aaatcccgcc tggtggaaga aaaacgccgg gcggcaaaac tggctgcgac gctggtagaa
    18001 cccgatcaga ccctcttttt tgactgtggc accaccacgc cgtggattat tgaagcaatt
    18061 gataatgaaa tcccttttac cgccgtttgt tattcgctaa atacttttct ggcgctgaaa
    18121 gagaaacccc attgccgcgc gtttctttgc ggtggtgaat ttcacgccag caacgccatt
    18181 ttcaaaccca tcgattttca gcaaacactg aataattttt gcccggatat cgctttttat
    18241 tccgctgcgg gcgtgcatat cagtaaaggc gctacctgtt ttaatcttga agagttgccg
    18301 gtaaaacact gggccatgtc gatggcgcaa aagcatgtgc tggttgtcga ccacagtaaa
    18361 tttggcaagg tgcgtccggc gcgcatgggt gacctgaaac gctttgatat tgttgtgagc
    18421 gattgttgcc cggaagatga gtatgtgaag tacgcgcaga cgcagcgtat taagttgatg
    18481 tattaatgac gtataaccgg atgacgtttc gcgccatccg gttatcagaa gattaagaga
    18541 accagctgcc gaaccactga tggaatttca tcatcacgaa atcccacatc cgaccaaaga
    18601 atccgccctc ttccacattt tccatcacga tcagcggacg ctgctcaatg gatttaccgt
    18661 taagctggaa atcaatggtg ccgacaacct gacctttttt cagcggtgcg gtaagctgcg
    18721 gttccgttaa cgtataactc gccttcaggt ttttcagctg cccacgcggt atggtcactg
    18781 agcccgcttc gcctgccccg agattcactt cgctcttatc accaaaccag acgcgctgag
    18841 tcacaaatgt ggcatcaggt ttaattggcg tcacggtttc aaagaagcgg aaaccccagg
    18901 tcaataattt ctcagactca ttaaaacgga tacggtcagt tttcgccccc agcactacgg
    18961 agattaaacg catatcgccc tgggtagccg aagcaaccag attatatccc gcgcctgccg
    19021 tggttcctgt cttcatgcca tcaacattca gattgctgct ccacagcaga cgattacggt
    19081 taggctgacg aattttgttg aaggtgaact ctttctcttt atgaatggcg tactcttccg
    19141 gcacatcgtg gatcaatgct ttacccagca atgccatatc gcgcgcggta ctgaactgcc
    19201 ccggcgcatc caggccgtgc accgtctgga aggtagtgtt ggtcagaccc agttttttgg
    19261 cataaccatt catcaaacca ataaatgact cctggctccc ggcaacgtaa tcagccagcg
    19321 caatacaggc gtcattaccg gactggataa tcacaccttt gttcaagtct gccaccgaaa
    19381 cctgatcgcc cggtttgagg aacattaccg atgaaccacg cagtgccgga tttcccgtcg
    19441 cccaggcatc tttaccgacc gtcaccatat cggtgagttt aattttatcg gccttaagcg
    19501 cctgcccaac cacatagctg gtcataattt tagtcaggct cgcgggatcc agtttctcat
    19561 ccgcattgcc ttctgccagc actttaccgc tggcgtaatc cattaaaatc catgcacggg
    19621 catccacgct cggcgcttca acggtttgtt ccgccgcgaa tgccgttggg gcaaaaagga
    19681 ataaaaatgc agaacccgct gcaagaccac gaaggagaga ggagtattgc gtcataaatg
    19741 ccacccgagt atccattcaa aaaaaatacg ttatatcgcc gtatgataag ttcggtgatt
    19801 aataacgcac acacaaactt aaagaaaccg taagttggta aagtttttaa agtttatgca
    19861 atatcctgcc gcttcgctgc ttctggtgtc atttttttgc cagctgttgc ttaaaagtta
    19921 actttacttc accatcggag tcctgtttag cctgtggctg cctgtcggaa aaggggtgag
    19981 tatgattacg ctgtggggtc ggaataattc aaccaacgta aaaaaagtat tgctgacgct
    20041 cgaagaactg gaactacctt atgagcaaat tctcgcgggc cgtgagtttg ggataaatca
    20101 cgatactgat tttctggcga tgaaccctaa cgggctggtg ccgttgttgc gtgacgacga
    20161 aagtgatctc attctttggg aatcaaacgc cattgtccgc tatctggcgg cacagtacgg
    20221 gcaaaaacgc ctgtggatcg actcaccggc acgtcgtgcg gaagcagaaa aatggatgga
    20281 ctgggcaaac cagacgctca gtaatgctca tcgcgggatc ctgatgggat tagtcagaac
    20341 accaccggaa gagcgcgatc aggccgccat tgatgccagt tgcaaagagt gcgacgccct
    20401 gtttgccctg ctcgatgcgg aattggcaaa agtaaaatgg ttctcaggcg acgagtttgg
    20461 tgtgggcgat atcgctatcg caccgttcat ctacaatttg tttaacgttg gcctgacctg
    20521 gacaccgcgt ccaaatctgc aacgctggta tcagcaactc actgaacgcc ccgcagtgcg
    20581 caaagtggtg atgattcccg ttagctaatt gcgtgggcta actttaagta attccccact
    20641 ggactcgtcg gtgagaacgt ataaataacc gtcgggtcca gtgcgaacat cacgaattcg
    20701 ttgccctctg tccgttaaaa tacggccatc ttctgtcact ttgtcgccgt tgacgctcat
    20761 cacaatgaca tctttatctt tcagcgcgcc aataaataat ttttgctgcc actgggggaa
    20821 tttgtcgctg ttatagaaag ccatgccgct cacggcgggc gaatctttcc agtaaaaaac
    20881 aggttgctcg gtcccggcga cgatctcccc tttcgcttcc ggtatcttaa agcccgaata
    20941 gttgattccc caggttgcca gcggccagcc gtagtttttg cctttttgcg gaatattaat
    21001 ttcatcacca ccgcgcgggc catgttcatt cagccatagt gcattactcc acggattcat
    21061 cgccattcct tgcggattac gaatgccata agaccagatc tcggcgcgca caccggattc
    21121 ctttataaaa ggattatcat ccgggatttc tcccaggtcg gtcagacgca ccagtttgcc
    21181 ctgtaattta tccagatcct gcgccgtcgg gcgctgattg ttttcgccca gagcaataaa
    21241 aagataacct ttaccgtcaa ataccatccg cccgccaaaa tggttgccgg tagacagttt
    21301 tggcatctga cgaaagacgg tgcggaagtc ggtcactttt gagagatcat cacttaagcg
    21361 accataaccc acagcagttc cggctttgcc atcatcgcca acttcggaat aacttaacca
    21421 gatgcggcgc gactgagcaa aatcgggcgc taaaaccacg tccagcaggc cgccctgccc
    21481 gtgcgcccaa acgtccggca ctccggaaag cggcgcagat aatccttttc ctgcttgcca
    21541 gtgacgcaac tcgccgccgc gcagagtgat taacataccg tgattatcgg gtaaaaaggc
    21601 cagcgcccag ggatggtcga gtttgtcttg cagtacttcg acatttaccg ttgcaggagc
    21661 cgcccagaga gcggaagaaa gacaaataag gggcacaagg aaaaaggatt gtcgatgcat
    21721 aacgcctccg gattgactct ggcttaaagc gtagtcagtg gaggagagaa caaattcatt
    21781 tttacaaaaa cttaaacatg aagggggaga cgctttctcc cccttagttt tcaggccttc
    21841 tcaagcatgg cgtgcttctg caggctctgg atactcagcg ttaagctcat cagacaattt
    21901 tcaagcttat cggcgttgac ggtaataaca gtcgggcaat catggtgccc actcatcaaa
    21961 catactgcgg ctgtcgctaa tgcttcttca gcatgatgaa gagcactcca ctcttcctga
    22021 tccagatgaa gattcaaccg cagcgattta tcgtgcagtt cgcgattcag tttaaaaaag
    22081 ttatctcgta gatgattgct ttcgctgacg gacatgtatc cttttgcctt cctcagttgc
    22141 acgtatgcgg cgaggtcaac gcgtgcgtcg atcaaccggt tcagcaggtc gattcgctgt
    22201 ctgtcaacga acatacttcg atcctcctct ttccagcctt gttgcaatta aatagtatgg
    22261 ctgttttttg agcaaaatgc tgtccaggat caattcttca cgccgaatta acaaaattta
    22321 catttccttc aactccgcca gcgaatgaga ttgcgataca aattttatcc agaactctgt
    22381 agaatccctg ccctgacctt tcctgtaact gaatattttt taagctatga gcaaagtaac
    22441 tccccagccg aaaatcggct ttgtttccct tggctgcccg aaaaaccttg tcgattcaga
    22501 gcgtattctc accgaactac gcactgaagg ttatgacgtg gtaccgagct atgacgatgc
    22561 ggacatggtg atcgtcaaca cctgcggctt tattgacagc gcggtacaag aatcactgga
    22621 agccattggt gaagcgttga atgaaaacgg caaggtaatt gtgaccggtt gtctgggggc
    22681 aaaagaagat cagatccgcg aagtccaccc gaaagtgctg gaaatcaccg ggcctcatag
    22741 ctatgagcag gttctggagc acgttcatca ctacgtgcca aaaccgaaac acaacccgtt
    22801 cctgagcctg gtgccagaac aaggtgtgaa actgacgccg cgtcattatg cttatctgaa
    22861 aatttctgaa ggctgtaatc accgctgcac cttctgcatt attccgtcta tgcgcggcga
    22921 tctggtgagc cgtccgattg gcgaagtgtt aagtgaagcg aaacgtctgg ttgatgcggg
    22981 cgttaaagaa attctggtga tctcgcagga tacttccgcg tatggcgtcg atgttaaaca
    23041 tcgtactggc ttccacaacg gcgagccggt aaaaaccagc atggtcagcc tgtgcgaaca
    23101 gttatcgaaa ctggggatct ggacacgtct gcactacgtt tacccttatc cgcatgtgga
    23161 cgacgtcatc ccactgatgg cagagggcaa aatcctgccg tatctggaca ttccgttgca
    23221 gcacgccagc ccgcgcattc tcaaactgat gaagcgtccg ggttctgtag atcgccaact
    23281 ggcgcgcatc aaacagtggc gcgaaatctg cccggaactg accctacgct caacctttat
    23341 tgttggcttc cctggcgaga cggaagaaga tttccagatg ctactcgact tcctgaaaga
    23401 agcacgtctg gatcgcgttg gctgctttaa atacagcccg gttgaaggtg cagacgccaa
    23461 tgccctgcct gaccaggttc cggaagaagt gaaagaagaa cgctggaacc gtttcatgca
    23521 gctgcagcag cagatttccg ccgagcgcct gcaagagaaa gtgggtcgtg aaattctggt
    23581 gattatcgac gaagtggacg aagaaggcgc gattggtcgc agcatggcag atgcaccgga
    23641 aatcgacggc gcggtttatc tcaatggtga aaccaacgtt aagccgggtg atatcctgcg
    23701 agtgaaagtc gagcacgccg atgagtacga tttgtggggt agccgggttt aattaattca
    23761 ggccgggcaa aatcatttgt ccggcctgcg aataatgatt actgccagct aatctgcgcc
    23821 ctgccgtttt tcttactctt atacagccgc tcatccgcca gcattttcaa tcgttcgacg
    23881 gtagtacatt catttgaatg cgctacaccg atactggtgc ttaaattaat gcttcccacc
    23941 tggaaatgaa cgatttcttt tagaatcgat agcaactctt ccagcgtgcc gccagtataa
    24001 atcaccgcaa attcgtcacc tccgaagcgg tagactttac ctttatctac cgggatctgt
    24061 gatttaagga ttttcaccac tttcatcaac acttcatcgc ccagcaaatg accgaaggtg
    24121 tcgttaatgt ttttgaattt atcgacgtca aacaggcaca aataaccgcc tttttccggc
    24181 agcgctttta aatcttcgtc aaaggatttt ctgcccatcg ctttggtcag gtcgtccagg
    24241 aatgccgagt tatacatact gtagagtttt ttgacatcgg cagccgaaaa gaaaagcccg
    24301 ccatccagta cgcgttcaaa atggttatta ataatggctt ctttctccac aataccacga
    24361 ttaatcactc tgcgtaccag atagaggcaa ctggcacccg atatcactgc caccaatgcg
    24421 gcaaagaaaa taatcaatgt acatacctga aaataaacgt cttttttata agcaaatacg
    24481 tacaatccgg tcggcaaata ggagaagtgc tccattgctt ccgaaacggt gaagatggcg
    24541 tttttagcgt tatattcatc accggtcacc gatttaccgt tcttgaacag ggagaacatc
    24601 aggttctcgc tatccatcgc cagcgatttt gacagtaaag aaaaacgttc cagaccaagc
    24661 aaaaatatca gactacgatt gtgagttacc ggatagaggt aatagacgaa ggttttacca
    24721 tcaaaagaga taaaccctgt atttttgaca tgtcgatact taacaacctg cataatatct
    24781 gcacaataat ttttctcaaa ctcctttacc tgaatacatt cgtcactgga aatcagataa
    24841 ggaccgacat cgtacaaata agagggtgaa accgagtcgg cgtaagctgt gcgtaagcca
    24901 accaacagct gttcctccgt aggatttagc gtgttgatca gatcaattgc cacactccgc
    24961 cgatattcag caatatttgc caccgcaaaa gcagtatcaa taacggactg tttcaggcca
    25021 tacacccgtt cctttaccat ttgagtgtag atcccgcagg caactgctga aatcatgata
    25081 aaaatcagca gactgactgt aagtacgaat ttattgattc tggacatacg taaactactc
    25141 ttttactaat tttccacttt tatcccaggc ggagaatggc atgggtttct ggtacagata
    25201 cccctgagcc tgaacacatc ctaatttgat taattcacgc gcaacgtctt cgctctctac
    25261 gccttccgca atcaccggga tccggttata gcgtgccaga tcgaaaataa tgcgcacaat
    25321 ttttcccgca gtaccgaaaa tatcgccggt aaattgcgaa tccaccttta tactgtctgg
    25381 attaatttca taaaaacgtt tcaggtttga caaaccggtg ccaaagtcat caatcgatac
    25441 ccgtacccct tgtttacgca gttgttcaat attgagatag aaatgttcat taattcgctc
    25501 gatcacggtt tcggtgatct caacacaaag gctgttcgcc ttcaggccat tttctttcat
    25561 gatggtagta aaacgctcat gaaagtgtgg ttcgtttaac tgccagggcg aaacattaat
    25621 atgcagtaag aaatcatcct tcagcgacgc acgctgacta aaatgtctga attcacccat
    25681 cgcggtttta ataatttgat agcccagctc attgataaac ccgatatctt cagcaatggt
    25741 aatgaacttc agcggtgaaa taatcccccg ctccgcagac acccaacggc acaacgcctc
    25801 cgcgcccaaa atggtgcggg tgttaatatc aacaatcggt tgatagacca ggaatagttc
    25861 gccaatttcc attgcatggc gaatattacg cgcaatccag atattctctt ctatttcgtt
    25921 gagtttcgca tcatcacaga aaataaactc tgagaacata tggttgcgga tactggaaat
    25981 cgccagtttc agcttttctg cgtaactcca ggcgttttcc ccctgcaaag gttcacaaat
    26041 agcagactta tggatgcgca gattgcggta gccaaaactg ctgtcaaaat cgtttaccgt
    26101 cgctatctta cgggtaaacg tctgtacatt ttcccggcac aggagtaaat agagatcggc
    26161 attaaatgtc acgatatcgc agcattgcgc atatttctcg gcaattcgct gacacaattt
    26221 cctgacgatt ttattgcgtt catcaacacc aaacaccgct tccacagctt ccagaccaca
    26281 cagtttgatg atccccacag ccagatactg attattgttg gactcaataa tcgccatatt
    26341 tttaataaaa ccgctttcct gatcgtaaga gatcagcgag agcaatttat ttgcccgttc
    26401 aatttcagca tctttcattt ccgcgatcga atttttgatg ctgataatct ctttcgcatc
    26461 gccttcacga atcttcaggg cctcgatttg atccgtagag tcaggcaaaa acgccagcgt
    26521 attgaccaaa tctgtcattt cagaaaattg acgacggaaa actcgagtgg tcattaaata
    26581 aaccaccagc aatacgataa taatgaaagc aaacggcaga taaaaaagtt tatctgatgc
    26641 gttcaataaa ttaccaccag gataataaaa atagatttcg aataatgcgt tgtttggcac
    26701 cgctgatgtt ttttcaatat attccgtatc gacagaatca ataatattat aattaccttc
    26761 gctattataa ataatcaatt tttcacgagc gagttgattc ttagcaatga tctcatgacc
    26821 tgctttaaaa atagaacttc atcattagcg ctgatgtgat caagatactc gttcagatat
    26881 cgccagttta aatcgacatg aattttatct accgctaaca aatcatgatc tttgccgttg
    26941 atgtgtagcg taaaagagat acatttttta cccggacgat caaagcaatt gtatgccggg
    27001 ttccagctgt tgttagagtc atctgaagcc atcgaccacg gtcgtttcga tgggttaaaa
    27061 tcggcaaaaa taacccgccc tgactcgtcg acaagcggtc catttacttg ttcctgatga
    27121 taaacaacga ttttatcatt cgccctccgc gaaaagagat aatatttatt atcatcaagt
    27181 accagtccca ccgagtctaa aaatggcatc atttccattt tcagaatcac ggcacgttga
    27241 atctcctctg tattttttaa taaatacagt gagtcc
//
LOCUS       DAFGPF010000063        27101 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFGPF010000063 DAFGPF010000000
VERSION     DAFGPF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27101
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.063"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            76..1119
                     /locus_tag="LSX49_002971"
     CDS             76..1119
                     /locus_tag="LSX49_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL7169356.1"
                     /translation="MQGIKIYTILASSLISGSVFAQTEISTSNSSTVNASYVEPSAEK
                     IISPSDKLNNLFERNMSQPYILQKIGERTYYVQRYFYSTTFYVGDKGVLLFDAPEGRG
                     KYLLQAIRDVTPLPVTALVYSHYHVDHIGDSPFWNDEAKKEGVNLRIIASKATAEKMQ
                     FMNSRLPVATQVLSKKDDQFKFEKQTIELHRFVKAGHTDDHSVWLLKQEKVAHSPDLL
                     NPDQLPMMGFAVSDTLVYHDSNLRQVEMLDWKYFIGGHGNIGSHDDFKFQRQFLNDLR
                     DTTIKVRKEESFGKFMNKTANNHADFARAQREAIIKKVTEVLRPKYGHMYGYDASMPA
                     NIEMAIRLVGSYY"
     gene            complement(1262..2626)
                     /locus_tag="LSX49_002972"
     CDS             complement(1262..2626)
                     /locus_tag="LSX49_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family transporter"
                     /protein_id="HBL7169357.1"
                     /translation="MSTITLLCIALAGVIMLLLLVIKAKVQPFVALLLVSLLVALAAG
                     IPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTI
                     AALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPP
                     HPGPVAAAGLLHADIGWLTIIGIAISIPVGIVGYFAAKIINKRQYAMSVEVLEQMQLA
                     PASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGS
                     PMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVES
                     GVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQC
                     VLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCV
                     WLVI"
     gene            complement(2715..3491)
                     /locus_tag="LSX49_002973"
     CDS             complement(2715..3491)
                     /locus_tag="LSX49_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBL7169358.1"
                     /translation="MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYDYSPQQ
                     IQQQLVQNHLTLALFNTAPGDINAGEWGLSALPGREHEARADIDLALEYALALNCEQV
                     HVMAGVVPAGEDAERYRAVFIDNLRYAADRFAPHGKRILVEALSPGVKPHYLFSSQYQ
                     ALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRNYAGKYAHVQIAGLPDRHEPDDGE
                     INYPWLFRLFDEVGYQGWIGCEYKPRGLTKEGLGWFDAWR"
     gene            complement(3496..4134)
                     /locus_tag="LSX49_002974"
     CDS             complement(3496..4134)
                     /locus_tag="LSX49_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBL7169359.1"
                     /translation="MSDFAKVEQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNL
                     LATPTGSCLGNLDPQRLSKVTADGEWLSGDNPSKEVLFHLALYRNNPLCKAVVHLHST
                     WSTALSCLEGLDSNNVIRPFTPYVVMRMGNVPLVPYYRPGDKRIAQDLAELAADNQAF
                     LLANHGPVVCGESLQEAANNMEELEETAKLIFILGDRPIRYLTAGEIAELRS"
     gene            complement(4131..5393)
                     /locus_tag="LSX49_002975"
     CDS             complement(4131..5393)
                     /locus_tag="LSX49_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxo-tetronate kinase"
                     /protein_id="HBL7169360.1"
                     /translation="MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAID
                     ALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDAL
                     MDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEA
                     QSTGRCGVVSAHVFEQGVKAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPL
                     VTGGSGLAIGLARQWAQENGNQAREAGRPLAGRGVVLSGSCSQMTNRQVAHYRQIAPA
                     REVDVARCLSTETLAAYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAQKAS
                     QAVETLFSQLAARLAAEGVTRFIVAGGETSGVVTQSLGIKGFHIGPTISPGVPWVNAL
                     DKPVSLALKSGNFGDEAFFSRAQREFLS"
     gene            complement(5390..6298)
                     /locus_tag="LSX49_002976"
     CDS             complement(5390..6298)
                     /locus_tag="LSX49_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL7169361.1"
                     /translation="MKTGSEFHVGIVGLGSMGMGAALSCVRAGLSTWGADLNSNACAT
                     LKEAGACGVSDNAATFAEKLDALLVLVVNATQVKQVLFGEKGVAQHLKPGTAVMVSST
                     IANADAQEIATALAGFGLEMLDAPVSGGAVKAANGEMTVMASGSDIAFERLAPVLEAV
                     AGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAG
                     NSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSAS
                     NAGYGKEDDSAVIKIFSGITLPGAKS"
     gene            6494..7261
                     /locus_tag="LSX49_002977"
     CDS             6494..7261
                     /locus_tag="LSX49_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7169362.1"
                     /translation="MIPVERRQIILEMVAEKGIVSIAELTDRMNVSHMTIRRDLQKLE
                     QQGAVVLVSGGVQSPGRVAHEPSHQVKTALAMTQKAAIGKLAASLVQPGRCIYLDAGT
                     TTLAIAQHLIHMEPLTVVTNDFVIADYLLDNSNCTIIHTGGAVCRENRSCVGEAAATM
                     LRSLMIDQAFISASSWSVRGISTPAEDKVTVKRAIASASRQRVLVCDATKYGQVATWL
                     ALPLSEFDQIITDDGLPESASRALAKLDLSLLVAKNE"
     gene            complement(7312..7968)
                     /gene="pphB"
                     /locus_tag="LSX49_002978"
     CDS             complement(7312..7968)
                     /gene="pphB"
                     /locus_tag="LSX49_002978"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HBL7169363.1"
                     /translation="MPSTRYQKINAHHYRHIWAVGDIHGDYQLLQSRLHQLSFCPETD
                     LLISVGDNIDRGPESLNVLRLLNQPWFISVKGNHEAMALEAFETGDGNMWLASGGDWF
                     FDLNDSEQQEAIDLLLKFHLLPHIIEITNDNIKYVIAHADYPGKEYQFGKEIAESELL
                     WPVDRVQKSLNSELQKINGADFFIFGHMMFDNIQTFANQIYIDTGSPKSGRLSFYKIK
                     "
     gene            complement(8074..10635)
                     /gene="mutS"
                     /locus_tag="LSX49_002979"
     CDS             complement(8074..10635)
                     /gene="mutS"
                     /locus_tag="LSX49_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL7169364.1"
                     /translation="MSTIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMERQQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLENVDSAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERL
                     EVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            10921..11265
                     /locus_tag="LSX49_002980"
     CDS             10921..11265
                     /locus_tag="LSX49_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HBL7169365.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYEALFAYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKK"
     gene            complement(11304..11732)
                     /locus_tag="LSX49_002981"
     CDS             complement(11304..11732)
                     /locus_tag="LSX49_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012134844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
                     /protein_id="HBL7169366.1"
                     /translation="MAVSARNQLTGTVSAVAMGAVNDEVELTLAGGAKLVAIVTHSSQ
                     QALGLAKGKEAIALIKAPWVTLATEDCGLKFSARNQFAGSVSTITEGAVNATVHIKTD
                     AGFEIVAVVTNESQDEMKLTTGSRVIALIKASAILIATKA"
     gene            complement(11777..13855)
                     /gene="flhA"
                     /locus_tag="LSX49_002982"
     CDS             complement(11777..13855)
                     /gene="flhA"
                     /locus_tag="LSX49_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HBL7169367.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRSILSRPDTLHCSYEEFC
                     ETWPQLATGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFNTWGNQIQTLCLLPLMSGDTMLGVLKLAQCEEKVFTTTNLNLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRILSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     ALPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            complement(13929..14939)
                     /gene="hypE"
                     /locus_tag="LSX49_002983"
     CDS             complement(13929..14939)
                     /gene="hypE"
                     /locus_tag="LSX49_002983"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HBL7169368.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLAPLIQTLRDIPGVKA
                     LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            complement(14936..16057)
                     /gene="hypD"
                     /locus_tag="LSX49_002984"
     CDS             complement(14936..16057)
                     /gene="hypD"
                     /locus_tag="LSX49_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HBL7169369.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA"
     gene            complement(16057..16329)
                     /gene="hypC"
                     /locus_tag="LSX49_002985"
     CDS             complement(16057..16329)
                     /gene="hypC"
                     /locus_tag="LSX49_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HBL7169370.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            complement(16320..17192)
                     /gene="hypB"
                     /locus_tag="LSX49_002986"
     CDS             complement(16320..17192)
                     /gene="hypB"
                     /locus_tag="LSX49_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HBL7169371.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     APEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     MDQWLNWLETQRCA"
     gene            complement(17196..17546)
                     /gene="hypA"
                     /locus_tag="LSX49_002987"
     CDS             complement(17196..17546)
                     /gene="hypA"
                     /locus_tag="LSX49_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HBL7169372.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            17758..18219
                     /gene="hycA"
                     /locus_tag="LSX49_002988"
     CDS             17758..18219
                     /gene="hycA"
                     /locus_tag="LSX49_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HBL7169373.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPVA"
     gene            18344..18955
                     /gene="hycB"
                     /locus_tag="LSX49_002989"
     CDS             18344..18955
                     /gene="hycB"
                     /locus_tag="LSX49_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HBL7169374.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCATVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANTNTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            18952..20778
                     /gene="hycC"
                     /locus_tag="LSX49_002990"
     CDS             18952..20778
                     /gene="hycC"
                     /locus_tag="LSX49_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HBL7169375.1"
                     /translation="MSAISLINSGVAWFVAAAVLAFLFSFQKALSGWIAGIGGAVGSL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFVSLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEIMALCAVFLTSNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCSPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            20781..21704
                     /gene="hycD"
                     /locus_tag="LSX49_002991"
     CDS             20781..21704
                     /gene="hycD"
                     /locus_tag="LSX49_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HBL7169376.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTVGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITPRITWAGFGFAFLAFVSLLAA"
     gene            21722..23431
                     /gene="hycE"
                     /locus_tag="LSX49_002992"
     CDS             21722..23431
                     /gene="hycE"
                     /locus_tag="LSX49_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HBL7169377.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWVTVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            23441..23983
                     /gene="hycF"
                     /locus_tag="LSX49_002993"
     CDS             23441..23983
                     /gene="hycF"
                     /locus_tag="LSX49_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HBL7169378.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWQFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            23983..24750
                     /gene="hycG"
                     /locus_tag="LSX49_002994"
     CDS             23983..24750
                     /gene="hycG"
                     /locus_tag="LSX49_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HBL7169379.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGEQDEQPADILHPDMVQPLRVKVDREARRLAGYRYGRQIADDFLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            24747..25157
                     /gene="hycH"
                     /locus_tag="LSX49_002995"
     CDS             24747..25157
                     /gene="hycH"
                     /locus_tag="LSX49_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase assembly protein HycH"
                     /protein_id="HBL7169380.1"
                     /translation="MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDDYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARAA
                     QTSQQKEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            25150..25617
                     /gene="hycI"
                     /locus_tag="LSX49_002996"
     CDS             25150..25617
                     /gene="hycI"
                     /locus_tag="LSX49_002996"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HBL7169381.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPADIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEE"
     gene            25642..25827
                     /locus_tag="LSX49_002997"
     CDS             25642..25827
                     /locus_tag="LSX49_002997"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169382.1"
                     /translation="MNIKTGMCAFLLSLVLPAQATSFTEYLPMSDSEYAQKRALKPLL
                     TMPYDAEQTWHFRKVGV"
     gene            25853..26272
                     /locus_tag="LSX49_002998"
     CDS             25853..26272
                     /locus_tag="LSX49_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7169383.1"
                     /translation="MTANAARAVKATRELVNAVPFLGGSDSEDDYREALELVEYLIEE
                     DDTNPLIDFLASRIAEYENNNEKFAEFDKAVAAMPVGVALLRTLIDQHNLTYADLKNE
                     IGSKSLVSQILSGQRSLTISHIKALSARFGVKPEWFL"
     gene            complement(26364..26801)
                     /locus_tag="LSX49_002999"
     CDS             complement(26364..26801)
                     /locus_tag="LSX49_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169384.1"
                     /translation="MGSWGMEALESDEGLDLINWVEEQLQDDSTFDAESIVQRLSQHE
                     DLFGFQGDEEFLYDNYDNNVIGLVELIIQKAAGKKITSSKQIDQLDGYQLTSTFSKKL
                     QGRLQTIDDTHEWIMLFEGRAREKAKAYLIELTDKLRVVKTTA"
BASE COUNT         6312 a         7087 c         7120 g         6582 t
ORIGIN      
        1 taacgtagta atatctaaaa taacagtctg ttcagagatg ctataaatca acaacacatt
       61 aataaaggac tacgtatgca aggcattaaa atatatacaa ttctagcctc ttctcttata
      121 tctggtagtg tttttgctca aacggaaatt tcgacttcaa attcgtctac agttaatgca
      181 agttatgttg aaccttcagc ggaaaaaata atatcgccaa gcgataaact caataacctt
      241 tttgaaagaa atatgtctca gccttatatt ttacaaaaaa ttggcgagag aacttattat
      301 gttcaacgct atttttattc cactacgttt tatgtcggag acaaaggggt tttgctgttt
      361 gatgctccgg agggtcgcgg taaatattta ttacaggcaa ttcgtgatgt gactccatta
      421 cccgtaacag cgctggttta ttctcattac catgtggatc acattggcga tagtccattt
      481 tggaacgatg aggcgaagaa agaaggcgtg aatctgcgta ttattgccag taaagccact
      541 gctgaaaaaa tgcaatttat gaacagtcgc ttacccgtcg ccactcaggt tttaagtaaa
      601 aaagatgacc agtttaaatt tgaaaagcag accattgaat tacaccgatt tgttaaagca
      661 ggacataccg acgaccattc tgtatggttg ctaaaacagg aaaaagtagc tcacagcccg
      721 gatctcctga atcctgacca actgccgatg atgggcttcg ccgtatcgga tacgttggtt
      781 taccatgaca gtaatttgcg tcaggttgaa atgcttgact ggaaatattt tattggcggg
      841 catggtaata ttggttcaca cgatgatttt aaatttcaac gccagtttct taatgatctt
      901 cgggatacga caattaaagt cagaaaagaa gaaagttttg gtaaatttat gaataaaacg
      961 gcaaataatc atgctgattt tgcgcgagcc cagcgcgaag caattattaa aaaagtaact
     1021 gaagtattac gtccgaaata tggccatatg tatggctacg acgcatctat gcctgctaat
     1081 atcgaaatgg caataaggtt ggtcggttct tattactaag ataaaatcaa cttgcaagag
     1141 actgtaatta tattgcaaag tgaaaattaa cctcggtagc gagatattac cgaggttaat
     1201 attggcatac attacaccct tatcaggcac ttaaacgata catcatatct tatctggatt
     1261 attagatgac gagccatacg caccaggtaa ttaagaatcc ggtaaaaccg agaatggtcg
     1321 ttaacactgt ccaggttttc agaccgtctg ctaccgacaa ccccagatat ttggtcacaa
     1381 tccagaaccc tgagtcatta atatgtgacg cgccaagccc accaaagcag gctgccagcg
     1441 tcaccaatac gcactgaatt ggattcaatc ccatcaccgc ttctgagagt aacccgccgg
     1501 ttgtcaggat tgctacggtt gctgacccct gcgatgcacg cagcgccagt gaaataataa
     1561 atgcggctgg taacagaggc aggtcaatca tttgtaacat gttggcaagg gctttaccga
     1621 cgcccgattc caccagcact ttgccaaata cccctccagc accagtaacc aaaatcacta
     1681 ccgccgcagt gggaagggca gagcccataa tgtcgctggt gtgttgtaag ctccagccgc
     1741 gacgtaaagc caataaccag aatgccagca ccagcgcaat cattagagct accattggtg
     1801 agccgatcaa ctgtagcgta ccaagcaggg gatgcgaagg cggcatcagt gttgcagaaa
     1861 ccgttcccgc catgataatc gcgataggaa taacaattag cgaggtgact aacgcgacgc
     1921 ccggtggatt tattttatcg cttaattttg tcgcgccttc ctcactggcc ggagccagtt
     1981 gcatctgttc cagtacctcg accgacatcg catattggcg cttattgatt attttcgctg
     2041 caaagtagcc aacaatccct acgggaatag aaatcgcaat accgatgatg gttagccagc
     2101 cgatgtctgc gtggagtaat cccgctgcgg cgacagggcc tggatgcggc ggtaccgcca
     2161 cgtgaacagt gagcatgatc ccagcgacag gcaggccaaa tttgagtggt gatattttgg
     2221 caaccttggc aaaaccgtaa atgattggcg caagaataat aaagccgaca tcaaagaaga
     2281 cgggaatgcc gaggaagaac gctgccagag tcagcgcagc gatagttcgt ttgtcaccta
     2341 acttgcgact gaaataatta gccagtgact ctgcaccacc agagtgttcg atcatacgcc
     2401 ccagcatagc gccaagacca ataataatag tgacggaacc aagcacaccg cccatcccgg
     2461 cgatcatcac tttacccact tcgcccgccg gtatacccgc cgcaagtgcg actaacaggc
     2521 tgacgaggag cagagcaacg aatggttgta cctttgcctt gatgaccagt agcaacagca
     2581 tgattacgcc agctaacgca atgcataaca atgtaattgt ggacatggga aaccctgtct
     2641 gaaagttata gttaacctac cccatccgta gatgggggga tgtatgggta cgttgtaatt
     2701 agggattgag cgaattagcg ccaggcgtca aaccagccaa gcccttcttt ggtgaggcca
     2761 cgaggtttgt attcacaacc gatccagccc tgatatccca cttcatcgaa caggcggaac
     2821 agccacggat agttgatttc tccatcgtcc ggttcatgtc gatcaggtag tccggcaatt
     2881 tgtacgtgcg catatttccc ggcgtagttg cggattaaat gtgtcaggtt gccatctact
     2941 ttttgcgcat ggaaagtatc tagttgaata aacacgttat ctcgcgcaac ctcttcaaca
     3001 atagccagtg cctgatactg gctggagaag agataatgag gcttaacgcc ggggctgagt
     3061 gcttcaacca atattcgctt gccgtgtggc gcaaagcggt cggcagcgta gcggagatta
     3121 tcaataaata ctgcccggta ccgttcagca tcttcgccag cgggcacgac gcctgccatc
     3181 acatggactt gttcacaatt gagcgccaat gcatattcca gtgccaggtc gatgtctgcg
     3241 cgtgcttcgt gctcacgtcc gggaagggcg gataatcccc attctcccgc attaatatct
     3301 ccgggagcgg tattgaacag cgccagtgtc agatggtttt gcaccagttg ctgctggatt
     3361 tgctgggggg agtagtcata gggaaacaga aactccacag catcgaaccc ggcttttcgc
     3421 gctgcggcga agcgttcaat aaaaggcact tcggtgaaca tcatggataa attagctgca
     3481 aaacgaggca ttgcattaac tccttaattc cgcaatttca cctgcggtca gataacggat
     3541 cgggcggtca ccgagaataa aaatcagctt tgccgtttcc tccagctctt ccatattgtt
     3601 ggcggcttct tgcaggcttt caccgcaaac cactgggcca tgatttgcca gtaaaaaagc
     3661 ctgattgtct gctgccagtt ccgccagatc ctgtgcgatg cgtttatcgc ccggtcggta
     3721 atagggcacc agcgggacgt ttcccatccg catcaccacg tatggtgtga acggacgaat
     3781 aacgttattg ctgtccagcc cttccaggca ggaaagcgcc gtcgaccacg tactgtgcaa
     3841 atgcaccacc gctttacaga gcggattgtt gcgatacagc gccagatgaa agagcacctc
     3901 tttcgagggg ttgtcaccac ttaaccattc gccatccgcg gtgactttgg aaagccgctg
     3961 cggatcgaga ttgcccaggc atgaacctgt cggtgtcgcc agtaaattcc cgtcaggtaa
     4021 aagcagcgac agattgccag ccgaaccggt tgcatatccg cgctgaaaga atgaactggc
     4081 aatccgcgtc atctcctctc gcaaagactg ctctactttt gcgaaatcgc tcatgataaa
     4141 aactctcttt gggctcgtga aaaaaaggct tcatcaccga agttgccaga tttaagggcg
     4201 agtgagacag gcttatccag tgcgtttacc cacggcacgc cgggggaaat ggttgggcca
     4261 atatgaaacc cttttatgcc caggctctgt gtgactacgc cggaggtctc accgcctgcg
     4321 acaataaagc gtgtcacgcc ttccgctgct aaccgcgccg ctagttgaga aaacagagtt
     4381 tctactgcct gactggcttt ttgtgcaccg tattgctgtt gaattgctgc caatgcgtca
     4441 gtgctggcgg tggcaaaaac cagtggagca agtacacttt cctggcccag aacccactct
     4501 gccagctcgt gtgcataagc ggccagagtt tcggttgaga ggcagcgtgc cacatcaacc
     4561 tcacgggctg gtgcaatttg acggtaatgt gccacctggc ggttggtcat ttgagagcat
     4621 gaaccggaga gcactacgcc gcgcccagcg agcggacgcc ctgcttcgcg agcctggtta
     4681 ccgttttctt gcgcccactg ccgggccagg ccaatcgcca gaccagaacc gcccgttacc
     4741 agtggggcat cgcgcaaggc ttccccctga atttccagat ggtgttcggt cagcgcatca
     4801 agcaccgcgt agcgatagcc ctcttgctgt aagcgagcca gctcctgacg aacggctttc
     4861 acaccttgtt cgaaaacatg tgctgaaacg acgccgcagc gccctgtgga ttgcgcttca
     4921 accagacggg gaagatagct gtcggtcatg ggatttaccg ggtgatggcg cattccggat
     4981 tcggccagca gttgattcat tacgaacaaa tacccctgat aaaccgtacg tccgttgact
     5041 ggcagggccg gagagaagac cgtaaacggt gtgtcgagag catccattaa tgcatcggta
     5101 actgggccga tattcccttt cgccgtactg tcgaaagtag agcagtattt gaaatagatc
     5161 tgtttgcaac cttgctgttg caaccagctc agagccgcca gcgattgctg tgtggcttca
     5221 accaccggac aggagcgcgt tttcaggctg atcaccagtg cgtcgattgc ttccggcatt
     5281 ttacctgttg gaacaccgtt aatttgtacc gttggtagac cgttttccac cagaaaactg
     5341 gcgatatccg tcgcgccggt aaaatcatca gcgataacgc caatcttgat catgatttcg
     5401 ctcccggtag ggtgatgcca gagaaaatct tgataactgc gctatcgtct tctttcccgt
     5461 aacccgcgtt actggcgctg gtgaacatat tcaatgctgt tgaggccaat ggcagcggga
     5521 agtgcagggc tttggcggta tcggcaacca gaccaagatc cttaacaaaa atatcgacgg
     5581 ctgaatgcgg ggtgtaatcg ccatccacca catgacgcat ccggttttcg aacatccatg
     5641 aatttccggc ggcattggtc acgacgtcat acatcacatc cagcgggatc cccgcacggg
     5701 ctgcaagcgc catcgcttcg gctccggcag caatatgtac gcccgccaac aactggtgga
     5761 taatttttac ggtcgaaccc agtcccggtt ctgctccgat gcgataaact tttccggcaa
     5821 cggcttccag cacgggtgcc agtcgttcaa aggcaatatc gctaccggag gccatgacag
     5881 tcatttcacc gttagcggct tttaccgcac caccagaaac cggcgcatcc agcatttcca
     5941 gaccgaatcc agccagagcg gtagcaattt cttgcgcatc agcattggcg atagtggaag
     6001 aaaccattac tgccgtaccg ggtttcagat gttgtgcaac gcctttttca ccaaacagca
     6061 cctgtttaac ctgggtcgca ttgaccacca gcaccagcag agcgtccagt ttttcggcaa
     6121 acgtcgcggc gttatcagaa accccgcaag caccagcctc tttcaacgta gcgcaggcat
     6181 tgctgttcag gtctgcgccc caggtagaaa gacctgcgcg gacacatgac agtgctgctc
     6241 ccattcccat tgaccctaag ccaacgatac cgacatgaaa ctccgatccc gttttcatct
     6301 gctctccttg ttaatttaag tgatattttg tttgatattg tgaatataag cgcggaaaga
     6361 taacgatatg gtgagctgat tcacaaaaat taacattgtg tgttatttta tgtgaactaa
     6421 gcgttagttg cgccgcgcac gtttcgcagg caaatagcgt agaatgtcag caggacaaag
     6481 gaaggagcaa aagttgatac ccgtagagcg tcgccaaatc atccttgaga tggtagctga
     6541 aaaaggcatt gttagtattg ctgaactaac ggacagaatg aatgtgtcac atatgaccat
     6601 tcgtcgggat ttacaaaaac tggagcagca gggagccgtt gtgctggtgt ccgggggcgt
     6661 ccagtctccg ggacgcgtgg cgcatgaacc ttctcatcag gtaaaaactg cgctggcaat
     6721 gacgcaaaaa gcggctattg gcaagctggc ggcaagtctt gttcagccgg gacgttgtat
     6781 ctatctggat gcgggaacga ccacgttagc gattgcacag catctgattc acatggagcc
     6841 actcacagtg gttactaacg acttcgttat tgcggactac ttgctcgaca acagtaattg
     6901 cacaattatt cacactggcg gcgcagtgtg tcgggaaaac cgttcctgtg ttggggaagc
     6961 cgctgcgacc atgctgcgta gcctgatgat tgatcaggct tttatttctg catcgtcatg
     7021 gagtgtgcgg gggatctcta cgccagcaga agataaagtc acggtgaaac gggcgattgc
     7081 cagtgccagc cgccagcgag ttttggtctg tgatgcgacg aaatatggac aggtggcgac
     7141 atggctggcg ttaccattaa gcgagtttga tcagatcatt actgacgacg gtctgccgga
     7201 gagtgccagc cgcgcgctgg cgaagctgga tctctctttg ctggtagcga aaaatgaata
     7261 atgacctgca ataacgccgg gttactcatg cttcacagaa gaagcatgag actactttat
     7321 tttataaaat gacagccgcc cgcttttcgg cgatccggta tctatataaa tctggttagc
     7381 gaacgtctga atgttatcaa acatcatatg accaaatata aagaagtcgg cgccgtttat
     7441 tttttgtaat tcgctattaa gtgatttctg cacacgatca acaggccaga gtaattcgct
     7501 ctccgctatt tctttgccaa actgatactc cttccccgga taatctgcat gtgcgatgac
     7561 atattttatg ttgtcgttag tgatttcaat aatatgtgga aggagatgga atttcagcaa
     7621 cagatctatt gcctcttgtt gctctgaatc atttaaatcg aaaaaccagt caccaccgct
     7681 ggcaagccac atatttccat cgccagtttc gaatgcctca agcgccatcg cttcgtggtt
     7741 gcctttgacg gagataaacc agggctggtt taacaggcgc agcacgttaa gactctccgg
     7801 cccacgatcg atgttatcgc ctaccgaaat aagtaagtcg gtttcaggac aaaaagagag
     7861 ttgatgtaag cgggattgta ataattgata gtcaccatga atatcaccaa cggcccatat
     7921 atggcgatag tgatgggcat tgattttttg atagcgtgta gatggcatgg ttttaccctg
     7981 taaaataagt tttcctatta tacagggtat ttttatttga ttcgtcagtt gtcgttaata
     8041 ttcccgatag caaaaggcta tcgggaatta ttattacacc agactcttca agcgataaat
     8101 ccattccagc gcctgacgcg gagtcagtga atccgggtcg aggttttcca gtgcctcgac
     8161 cgcaggcgaa gtttcttccg gtacggacag caaagacatt tgtgtaccat ccacttgcgt
     8221 agcagcggcg ttcggcgaaa tgctttccag ctcacgcagt ttttgccgtg cgcgcttaat
     8281 aacctctttt ggcacacccg ccagagctgc aaccgccagg ccgtagcttt tgctcgccgc
     8341 gccatcctgc acgctatgca taaaggcaat ggtgtcgccg tgctccagtg catcgagatg
     8401 cacgttggcg acgccttcca ttttctccgg taactgggtc agctcgaaat agtgggtagc
     8461 aaacagcgtc aacgctttga tcttatttgc cagattttcc gcacacgccc acgccagcga
     8521 cagaccatcg taagtggacg ttccacgccc gatctcatcc atcaacacca gactatattc
     8581 ggtggcgtta tgtaaaatat tggcggtttc ggtcatctcc accataaagg ttgaacgccc
     8641 ggaagccaga tcatccgcag cacctacgcg ggtaaagata cggtcaatcg ggccaatctc
     8701 gactttttgc gccggtacgt agctgccgat atacgccatc agcgcaatca acgcggtctg
     8761 gcgcatatag gtacttttac cgcccatgtt cggaccggta atgatcaaca tgcgacgctg
     8821 cggcgacagg ttcagcgggt tagcgataaa cggctcattc agtacttgtt caactaccgg
     8881 atggcgacct tcggtaatac gaatgccagg tttatcaatg aaggtcgggc aggtatagtt
     8941 cagggtatag gcccgttccg ccaggttcac cagcacgtcg agttccgcca gcgcgctcgc
     9001 gctctgttgc aacgcttcca gatgcggcaa cagcaggtcg aacagctctt cataaagttg
     9061 tttttccaga gccagtgctt tgccttttga ggtgagaact ttatcttcgt actcttttag
     9121 ctctggaatg atgtagcgct cggcgttttt cagcgtctgg cgacgcatgt agttgattgg
     9181 tgccaaatgg ctttgcccac ggctgatttg aatgtagtag ccgtgcaccg cattaaagcc
     9241 aactttcagc gtgtccaggc cggtacgttc acgctcgcgg acttccagac gctccagata
     9301 atcggtcgcg ccgtcagcca gcgcgcgcca ctcatccagc tcttcgttat agcccgatgc
     9361 gataacacca ccgtcgcgta ccagcaccgg tggtgtgtcg atgattgctc gctccagcag
     9421 atcgcgcagc tcggcaaact cgcccatctt ctcacgcagc gcttgtaccg gtgcactatc
     9481 gacattttct aactgcgcac gcaactccgg cagttgctgg aaagcgtgac gcatacgggc
     9541 cagatcgcgt gggcgagcgg tacgcaacgc cagacgcgcc agaatacgtt ccaggtcgcc
     9601 cacctgacgc agtaccggct gcagctcggc ggtgaaatcc tgcaatgcgc caatagtttg
     9661 ctgacgctca agcaacacgc gggtatcgcg cactggcata tgcagccagc gtttcaacat
     9721 acgactaccc atcggcgtta cagtgcagtc gagcactgaa gccagcgtat tttccgcacc
     9781 gccggccagg ttctgagtaa tttccaggtt acgacgcgtc gcggcatcca taatgatgct
     9841 gtcctgctga cgttccatag tgatagaacg gatatgcggc agggtcgtgc gttgggtatc
     9901 tttcgcatac tgcaacagac aaccggcagc acaaagtccg cgtggtgcgt tctccacacc
     9961 aaaaccgacc agatctcggg tgccaaattg caggttcaat tgctggcgag cggtgtcgat
    10021 ttcaaactcc cacagcgggc gacgacgcag gccgcggcga ccttcaatca gcgacatctc
    10081 ggcgaaatct tctgcataca gtaattccgc tggattcgta cgttgcagtt ctgccgccat
    10141 cgtttcgcgg tccgccggtt cgctcaggcg aaaacgaccg gaactgatat ccagcgttgc
    10201 gtagccgaaa cctttactgt cctgccagat agccgccagc aggttgtcct gacgttcctg
    10261 caacagcgct tcatcgctga tggtgcccgg cgtaacgata cggacaactt tgcgctcgac
    10321 cggccctttg ctggtcgccg gatcgccaat ctgttcacaa atagcgacgg attcgccctg
    10381 attcaccagt ttggcgaggt agttttccac cgcatggtag ggaatccccg ccatcgggat
    10441 tggctctccc gctgaagcac cgcgtttggt cagtgaaata tccagcagtt gcgacgcccg
    10501 ttttgcgtcg tcataaaaca gttcataaaa gtcgcccatc cggtaaaaca gcaggatctc
    10561 gggatgctgg gctttcagct tgagatactg ctgcatcatg ggcgtatggg cgtcgaaatt
    10621 ttctattgta ctcatggggt taagtccggc tccctgatgt taaatgtagt gtgatggttt
    10681 ttattttcgt tgtaatcaca taaggcgcac atgataccgg agttaatcat ttcaggggaa
    10741 gacgcgaaag gtgagttctt gatgtcggtt ccgcgaaaaa tgctgctttg cagcttttgc
    10801 gtgatgacga tgaaacaaga tcgccaaatt cgtcggttga agaaacctcc tccttcagag
    10861 ccatagtccc ctttaaaatt aagttgtaat ataaatgcac cttaagagta tggaggcagc
    10921 atgtccggca agcgtatctc tcgtgaaaaa ctgacgatta aaaaaatgat cgatctttat
    10981 caagcgaaat gcccgcaggc gtcagcagag ccggagcatt acgaggcgtt gtttgcttac
    11041 gcgcaaaagc ggctggataa atgtgtgttc ggcgaagaga aaccagcctg taagcagtgt
    11101 ccggtgcact gttaccagcc tgcaaagcgt gaagagatga aacagattat gcgttgggcc
    11161 gggccgagaa tgctgtggcg tcatccgatc ttaaccgtgc gtcatctcat cgatgacaag
    11221 cgtccggtgc cggagttgcc agaaaaatat cgtccaaaga aataaatctg ccggagagcc
    11281 atactctccg gcaaatacgg cgcttacgct ttggtggcaa tcaggatggc tgatgctttg
    11341 atcaatgcaa taacgcgcga gccagtggtg agtttcattt catcctgact ttcatttgtt
    11401 accactgcca caatttcaaa acccgcatcc gttttgatat ggacagtggc gttcactgcg
    11461 ccttcggtga ttgtcgacac gctgccagca aactggttgc gagcagagaa tttcagtcca
    11521 cagtcttccg ttgccagcgt tacccacggg gctttaatca gggcaatcgc ttctttccct
    11581 ttcgccagac ccagcgcttg ctggctgctg tgagtcacaa ttgccaccag ctttgcacca
    11641 cctgccagcg tcagttctac ttcgtcattc accgcgccca ttgctactgc gctaactgtt
    11701 ccggttaatt gatttcttgc tgaaactgcc atactgcctc ctttcattga atgttgatcg
    11761 agtataacca catctgttaa atcaatgccg atttatcaat tcccagtcgc ttcattcgtg
    11821 acagcagagt cgtgcgtttc agccccagac gttgcgcagc gcctttaggc ccggcaacca
    11881 cgccgtttgt ttctttcagc acgcgaacaa tcaactgata ttcatcttcg ccctcctggg
    11941 cgacaaccgt tgcggcaggc ggcgtttcag gttctggtaa agcaatatct ggcaatgaca
    12001 gctgcagcac gttgccgcgt gttagcaata ccgcgcgctc gatgacgttt tccagctcac
    12061 gcacgttgcc cggccattcc atgttgctca ggatgcgcag cgtctcggca ggaatgctgt
    12121 cgatattgcg ccccagacga cgggcaattt tgaaggtaaa ggctttcgcc agcagcggaa
    12181 tatcttccgg acgctcgcgt agtggcggca ggtggatcgg gaatacgttc aggcggtaat
    12241 agagatcgct acggaactct cggtcggcga ccattttttt cagatcgcgg ttagtcgcgg
    12301 caattaaacg tacgtccgtc tgaatgattt tgttgctgcc gagacgttca aactcctgtt
    12361 cctgtaatac acgcagcaac ttcggctgta actccagcgg catatcgccc acttcatcga
    12421 ggaatagtga gcttttatcc gccagttcaa aacgaccaat gcgctgagcg ctggcaccgg
    12481 taaaagcccc gcgctcatga ccaaatagat cgctttccag caatccggca ggcatcgccg
    12541 cgcagttcat tttgaccatg cggcgattat tacgcccact gagattatgg atcgcgcggg
    12601 caatcagctc tttacctgta ccagtttcac cgaggatcag aacggtactg tcactttgcg
    12661 ccaccatttc aacttgttta agtacgctgt acatggcttc gctgcggcca ataatctcgc
    12721 caaattcact atcaacattg ttgagctgct cggtcagggc gaggttttca tcaaccagcc
    12781 gttctttcag acgatgaatt tcctgatagg cgagggcgtt atcgacagcg attgccacac
    12841 gttcggcaat ctggcgcagt aaattcagat tggtagtggt aaagactttc tcttcgcatt
    12901 gcgccagttt cagtacgccc agcatggtgt cgccagacat cagcggtaac aggcacaagg
    12961 tttgaatctg attgccccag gtgttgaaca acatgcgttc atagggggct aaatcgtccc
    13021 gctcgtggag attaatcaac agcatctctt tacttttgaa gacgcgttcg gtgagggttc
    13081 cggcttcatc gacttcgctc tgttcgtgag cgggatgctg tttatcaaga tagtgagtgg
    13141 agtagatgtt gagtttgttc ttacggtggc tgcgtaagac gatgctgata tcgtcaatgt
    13201 cgaagtagta gtggatttct ttggcgactt cgctgaccag ttcgtccata tccaggcggg
    13261 aaagcaccgc gttagtgatg gcgaccagga tgcggaagtt atcgcgttcc cggcataaca
    13321 actcatagtc gacattgtta acgacgcggc tctggatttg ttcggtgacg acagaaacga
    13381 tctgcgtaaa tgtttgcaga cgattgaact ctttttcgct ccaggggcga tcgtcataac
    13441 gaataaattc acagccacca aaaatatgcc cttccgccgc cagtggcatc aggcaatagt
    13501 gaccaaattt ggggtatagc ccacctgtgg ccagctgcgg ccaggtttca caaaattctt
    13561 cgtaactgca atgcagcgta tcagggcgcg acaaaatgct gcgtaccgga ccgtgtgcca
    13621 gaacagtttc gtcttcatat ttaatggggg tgtctttttc acgcgatgcg taataagacg
    13681 cacgttgagt ctgcgcttgc cacaacacaa tcgccgcgtt gtcggcgagc gcagaacgct
    13741 ttaccagttg cgaaagagcc tcacacagcg aggccagatc gggctgctgc aatagtgtcc
    13801 gagtgatgtc gaacaaccct tgctgtccga gatcactcat cggtgtatat gacattttgt
    13861 tcttccagga aagcaccgca aagcggtgca aaaggtcatt gactaactat aggagattta
    13921 gaattttatt agcatatacg cggaagcggt tcggcgtgcg gtagatcgag ggttcgtttc
    13981 acgccataca gaccggcaag acgaacacct ttacgttcta ctacttcgcc aatcagcgcc
    14041 gcatcttttc ccaatggatg ggaatgtaac gccgccagca cttgctctgc tgcgttgcgt
    14101 tcaacggcga tcaccagttt gccttcgttg gcaaagttaa gggcgtccag tcccagcagt
    14161 tcgcaaacgc cgcgcacagc aggtttaacc ggcagtgccg cttctgaaag ttcaatacca
    14221 caaccgcagg ctgccgcgaa ctcatgaacc accgcgttta caccaccacg ggtggcatca
    14281 cgcagcgctt tcacgccggg aatgtcacgc agcgtctgaa taagcggcgc cagcaccgcg
    14341 cagtcgctga ccagttctcc atccagccct agttgctcac gcaggttaag gatagtcgcc
    14401 ccatggtcgc cgagtgtacc gctaaccagc aatacatcgc ctgcggttag cgtctgtgcg
    14461 ccccagtgaa tattcgccgg aattgcgccc atgccagcgg tgttgataaa cagtttatct
    14521 gccgcgccgc gctgtaccac tttggtgtcg ccagtaacga tggcaatgcc tgccgcacgg
    14581 gcggtttctg ccatgctggt cactacggct ttcagtgtct ccatcggcaa tccttcttcg
    14641 aggataaagc cacaggagag atagcgcgga attgcgccac tgaccgcaac gtcattggcg
    14701 gtgccgcaaa tcgccagctt gccgatatta ccgccaggaa agaacagcgg gtcaatgacg
    14761 taactgtcgg tggagaacgc cagacggtcg ccttccgcta ccagctgtgc caaatcaaga
    14821 cgggcctgat cttcctgctc tgccagccac gggttggcaa aggcttccat aaacaggctg
    14881 ttgattaatt gctgcatcgc ctggccgccg ctgccgtggg cgagttggat attattcacg
    14941 cttcactctc ctgctgacga tactgatacc acgcggcgca cgctccttcg gaggaaacca
    15001 tcagcgcacc aaacgcggtt tgaggattac aggtgttacc aaacagcggg cattgatgcg
    15061 gcttacattt gcccgtcaag acttcgccac aacgcgcacg cgggtcatcg cagacctgct
    15121 gcggtgccgg gcggaaatgt gcttcggcat cgaatcgttg ataatccggc gtcaggtgca
    15181 cgccagaaga ttcaatcacg cctaagccgc gccattcact gtcgccgttg acacagaaca
    15241 catcagcaat ggcctgttgc gccagcaggt taccggcatc cggtaccacc cgacgatact
    15301 gattctctac cttgctgtgg gccgctattt tctgctccac cagcatcacc acgccttgaa
    15361 gtagatcaag gggttcgaaa ccagcgacca ctagcggacg atgaaaatcg ctggcgataa
    15421 aattataggc atcagtgccg ataaccatac tgacgtggcc cggcgcgagg aacgcgtcga
    15481 taccgttatc tggctgttcc agcaaactgc gcagtgtcgg gataagcgta atgtgctggc
    15541 agaagaagta aaaattctgc acatcgcggg ctttcgcctg ttgcagagtg atggcggtgg
    15601 tcggcatggt ggtttcaaaa cctaagccga agaataccac tttacgggtt ggattctcct
    15661 gcgccagttt caacgcatcc attggcgagt aaacgatgcg cacatcggca ccgcgtgctt
    15721 ttgcctgcaa cagcgacccc tgtttccctg gtacgcgcat ggcatcgcca aaggtacaga
    15781 agatgacttc cggatggctg gcaatctcca cgcaggtgtc gattctaccc attggcagta
    15841 cgcacaccgg gcaacccgga ccgtggataa actcaacgtt ttccggtagc aactggtcga
    15901 ggccgaattt aaaaatggcg tgggtatgac cgccacacac ttccataatc cgcagagggc
    15961 gttcggcggt gtaagagaga tgtgaagcac gttcgcgcag atgctcaatt aactgcatta
    16021 cctgttccgg cgcgcgatat tcatcaacaa aacgcattat ttttcctcgc catacaacag
    16081 cgcgccgaca tctggctcaa cgtcaaacat gttttgtaag gcgtcgagag tgtcgcgtgc
    16141 ttcggcttca ttaattacgc tcatggcaaa gccaacgtga accagtaccc actggcccac
    16201 gcgtggctga ccgttttcat cgcagctgcc gactaacgtt aaatcgacat cgcgttgaat
    16261 gccgcagacg tcgactttcg cctggttgcc gtcaatggtg cggatctggc cgggaacgcc
    16321 tatgcacatc gctgtgtctc cagccagttc agccactggt ccatcccttc gccgctggtg
    16381 gcggaaataa ggatgatttc aatttctgga ttgacttcac gggcgcaggc gatgcacttc
    16441 tcaacgtcaa agttgagata cggcagcaag tcaactttgt tgagcagcat cagcgaggcg
    16501 gcggcaaaca tgtgcggata tttcagcggt ttgtcttcac cttcggtaac ggaaagcacc
    16561 gccactttgt gtttttcacc gagatcgaag ctggccgggc aaacgaggtt accgacgttt
    16621 tcgataaaca gaataccgtt atcgtccagt ggcaggcgcg gcgcggcgtc ggcaatcatc
    16681 tgtgcgtcaa gatggcagcc tttaccggtg ttcacctgaa tcgctggggt gccggtagcg
    16741 cgaatgcgtg cggcatcgtt cacggtttgc tggtcacctt caataaccgc gcacggaacg
    16801 ctgtctttca ggcgcattaa agtttccgtc agcagggtgg ttttaccgga accagggctg
    16861 gaaaccaggt tgagcaccag ttgcttgcgg gcagcaaagc gcgcgcggtt gcgttcagcc
    16921 agacggttat ttttgtccag cacgtcaatt tcgacttcca gcatccgacg ctggctcatg
    16981 cccggcgcgt gagtgcccgc ttcgccatga ccgtaatgca gatcgccttc ttcagtctgg
    17041 ctgggggtaa attcaggcgc tttaatgccg gtgattttca tcttcgggcg tgccgccggg
    17101 gcaaatggcg cgctacgaaa cgcggaatga gggttatgtt catcaccctc gatatagagg
    17161 ttgccttcac cgcaaccgca tgttgtacac atcgctcact cctggtctat ttctatccgc
    17221 cgaatctgta aaccgtcgtc tgccacaatc tgtagcatgt caccatgaca ctgtggacag
    17281 cggcggacgc gctgggtcag tagcgtcaca tactgttggc atgtttcaca ccagcattcg
    17341 gcctcttgtt cttcgaggtg cagtttacaa ccttccgcca cgctgccgcg gcaaaccaga
    17401 tcaaaacaaa aggcaagaga gctggtttcg acacaagaaa atgcgccaat tttgagccag
    17461 accccagtta cgcgttttgc gccgtgtttt gcggcctgct gttcgatcaa ttccagtgcc
    17521 cgttggcaga gggttatttc gtgcatatcg cctcccatta actattgcca gctacaagca
    17581 ataattgcgc cagtgttgat tatccctgcg gtgaataatg tcgatgatgt cgaaatgaca
    17641 cgtcgacacg gcgacgaaat tcatctttag cttagaaatc gctttaataa caatgaatta
    17701 aaagttggca cagaaaatgc ttaaagctgg catctctgtt aaacgggtaa cctgacaatg
    17761 actatttggg aaataagcga gaaagccgat tacatcgcac agcggcatcg tcgcctacag
    17821 gaccagtggc acatctactg caattcgctg gttcagggga tcacgttatc gaaagcgcgc
    17881 ctgcatcacg ccatgagctg cgcgccggac aaagaactct gtttcgtcct ttttgaacat
    17941 tttcgcattt acgtcaccct ggcggatggc tttaacagcc acaccatcga gtattacgtc
    18001 gaaacaaaag atggcgaaga caaacagcgg attgcgcagg cgcagttgag cattgacggc
    18061 atgattgatg gcaaggtcaa catccgcgat cgcgaacaag ttctggaaca ctatctcgaa
    18121 aaaatcgctg gcgtttacga cagcttatat accgccattg aaaacaatgt gccggtgaat
    18181 ttaagccaac tggtaaaggg acaaagcccg gtagcatgag ctgaggcttt gcccgttttg
    18241 caggcgttac gcctgtttgg ggatgggcgt gtcgatgagt gtcgaaaatg acatttcatc
    18301 ggcatgtttt cgtcaaaaat gacaatcacc tgaggaatgc ctggtgaatc gttttgtaat
    18361 tgctgactcc acgctctgta tcggctgcca cacttgtgag gctgcctgtt cagagacgca
    18421 tcgccagcac ggcctgcaat caatgccgcg cctgcgagtg atgctcaatg aaaaagaatc
    18481 tgcgccgcag ctctgtcacc actgtgaaga tgcaccctgc gcaacggtct gcccggttaa
    18541 cgccatcact cgtgttgatg gtgccgtaca gctgaatgaa agcttgtgcg taagctgcaa
    18601 actgtgtggc atcgcctgcc cgtttggcgc aattgaattt tccggcagcc gtccgctgga
    18661 tattccggca aacaccaata ccccgaaagc gccaccggca ccgcctgctc cggcgcgtgt
    18721 cagcacattg cttgactggg tgccaggtat tcgcgcgatc gccgtcaaat gtgacctttg
    18781 tagctttgat gaacaaggtc cggcctgcgt gcggatgtgc ccgactaaag ccctgcatct
    18841 ggtggataac accgatatcg cccgcgtcag caaacgtaag cgtgagctga cttttaacac
    18901 ggactttggc gatctcacct tgtttcagca ggctcaaagt ggagaggcta aatgagcgca
    18961 atttccctga tcaatagcgg cgtggcgtgg tttgtcgccg ccgctgttct ggcatttctc
    19021 ttttcttttc aaaaagcgct aagtggctgg atagccggaa ttggcggcgc ggtgggtagc
    19081 ctgtatacgg cagccgcggg cttcactgtg ctgactggcg cggttggcgt gagcggtgcg
    19141 ctgtcgttgg taagctacga tgtgcaaatc tctccgctta acgcgatttg gctgattacg
    19201 ctcggtctgt gcggtctgtt tgtcagcctc tacaacattg actggcatcg ccacgcgcag
    19261 gtgaagtgca acggcttgca gatcaatatg ttgatggctg ccgccgtctg tgccgtcatc
    19321 gccagcaacc tcggcatgtt cgtggtaatg gccgaaatca tggccctgtg tgcggtgttc
    19381 ctcaccagca acagcaaaga gggcaaactg tggtttgcgc tggggcgtct tggcactctg
    19441 ctgctggcga ttgcctgctg gctgctgtgg cagcgttacg gcacgctgga tctgcgcctg
    19501 ctggatatgc gtatgcaaca gctgccgctc ggttccgata tctggctgct cggtgtgatt
    19561 ggctttggcc tgctggccgg gattattccg ctgcacggct gggtgccaca ggcacatgcc
    19621 aacgcctctg cgccagctgc cgcgctgttt tccacggtag tcatgaaaat tggcctgctg
    19681 ggcattttaa ctctgtcact actgggcggt aatgcaccgc tgtggtgggg gatcgcactg
    19741 ctggtactcg gcatgatcac cgcattcgtc ggcggtctgt atgcgttgat ggaacataat
    19801 atccaacgtc tgctggctta ccacaccctg gaaaatatcg gcatcatcct gctggggctg
    19861 ggcgctggcg taacgggtat cgcgctcgaa caaccggcgc tgattgccct tggtctggtt
    19921 ggtggtctgt accatctgct taaccatagc ctgttcaaga gcgtactgtt ccttggtgcg
    19981 gggagcgtct ggttccgtac cggtcatcgc gatatcgaaa aactcggtgg tattggcaag
    20041 aaaatgccgg ttatctccat cgccatgtta gtcgggctga tggcaatggc tgcgctgccg
    20101 ccgctgaacg gttttgccgg ggaatgggtt atctatcaat ccttcttcaa actgagcaat
    20161 agtggcgcgt ttgttgcccg tcttctcggg ccgctgctcg ccgtggggct ggcaattacc
    20221 ggtgcgctgg cggtgatgtg tatggcgaaa gtttatggcg ttactttcct cggcgcgccg
    20281 cgtaccaaag aagccgaaaa cgccacctgt tcgccgctcc tgatgagcgt aagcgtagtg
    20341 gcactggcga tttgctgcgt aattggcggt gttgctgcgc cgtggctact gccgatgctc
    20401 tctgctgctg tacctctgcc gctggagcct gctaacacca ccgtttctca accaatgatc
    20461 acgttgttgt tgattgcctg cccgctgctg ccattcatca ttatggcgat ttgcaaaggc
    20521 gatcgtttgc cgtcgcgttc ccgcggcgcg gcctgggtgt gcggctacga tcatgaaaaa
    20581 tcaatggtga ttaccgctca cggttttgcc atgccggtga aacaggcgtt tgcgccggtg
    20641 ctgaaactac gcaaatggct gaatccggtg tctctggtgc cgggctggca gtgcgagggg
    20701 agtgcgttgc tgttccgccg gatggcgctg gttgaactgg cggtgctggt ggtgattatt
    20761 gtttcacgag gagcctgaga atgagtgttt tatatccgtt aattcaggcg ctggtgctat
    20821 ttgccgttgc gccgctgctc tccggtatta cccgcgtagc acgcgcccgt ctgcataacc
    20881 gtcgtgggcc gggtgtgttg caggagtatc gcgacattat caaactgctg ggccgccaga
    20941 gcgttggccc ggatgcctcc ggctgggtgt tccgcctgac gccgtatgtg atggtgggcg
    21001 tcatgctgac tatcgccact gcgctgccgg tggtgaccgt cggttctccg ctgccgcaac
    21061 tgggcgattt gatcacctta ctgtatctct tcgccatcgc gcgtttcttc tttgccattt
    21121 ctggtctgga taccggtagc ccgtttaccg ctatcggcgc gagccgtgaa gcgatgcttg
    21181 gcgtgttggt tgaaccgatg ctgctgcttg gtctgtgggt cgccgcacag gttgccggtt
    21241 ccaccaacat cagcaacatc accgacaccg tttatcactg gccactgagc cagagcatcc
    21301 cgctggtgct ggcgctttgt gcctgtgcat tcgccacctt tatcgaaatg ggcaaactgc
    21361 cgttcgacct ggcggaagcc gagcaggagt tgcaggaagg tccgctctct gagtatagcg
    21421 gcagcggctt tggcgtcatg aaatggggta tcagcctgaa acagctggtg gtgttgcaga
    21481 tgttcgtcgg ggtgtttatt ccgtggggac aaatggaaac cttcaccgtc ggtgggctgc
    21541 tgctggcgct ggtgattgcc atcgtcaaac tggtggttgg cgtcctggtt atcgcgctgt
    21601 tcgaaaacag catggcccgt ctgcgtcttg atattactcc gcgcattacc tgggccgggt
    21661 ttggctttgc atttttagcg ttcgtctcct tgctggcggc gtgattaaag agagtttgag
    21721 catgtctgaa gaaaaattag gtcaacatta tctcgccgcg ctgaatgagg catttcctgg
    21781 cgtcgtgctg gaccacgcct ggcagaccaa agatcagctg accgtgaccg taaaggtgaa
    21841 ctacctgccg gaagtggtgg agtttctcta ctacaagcag ggtggctggc tgtcggtgct
    21901 gtttggtaac gacgaacgca aactgaatgg tcattacgcc gtttattacg tgctgtcgat
    21961 ggagaagggc accaagtgtt gggtaacggt tcgcgttgaa gttgacgcca acaaaccgga
    22021 gtatccttcc gtgacgccgc gcgttccggc ggcggtgtgg ggcgagcgtg aagtgcgcga
    22081 tatgtacggt ttgattccgg ttggtctgcc ggatgaacgc cgtctggtgc tgccggatga
    22141 ctggccggat gaactttatc ctctgcgtaa agacagcatg gattatcgtc agcgtccggc
    22201 accgactacc gatgctgaaa cctacgagtt catcaacgaa ctgggcgaca agaaaaacaa
    22261 cgtcgtgccg attggtccac tgcacgtcac ttctgacgaa ccgggtcact tccgtctgtt
    22321 cgtcgatggt gaaaacatta tcgacgccga ctaccgcctg ttctacgtcc atcgcggcat
    22381 ggaaaaactg gcggaaaccc gtatgggtta caacgaagtg accttcctct ctgaccgtgt
    22441 gtgcgggatc tgcggctttg ctcacagcac cgcctatacc acgtcggtgg aaaacgcgat
    22501 gggtattcag gtgccagaac gcgcgcagat gatccgcgcc attctgctgg aggtagaacg
    22561 cctgcactcg catctgctca acctcggcct ggcctgtcac tttaccggct ttgactccgg
    22621 ctttatgcag ttcttccgcg tgcgtgaaac ctccatgaaa atggcagaga tccttaccgg
    22681 tgcgcgtaaa acctacggcc tgaacctgat cggcgggatt cgtcgcgatc tgctgaaaga
    22741 cgacatgatt cagacccgcc agctggcgca acagatgcgt cgtgaagtgc aggagctggt
    22801 ggatgtgctg ctgagcacac cgaacatgga acagcgcacc gtcggcattg gtcgtctgga
    22861 cccggaaatt gcccgcgatt tcagtaacgt tggcccgatg gtccgcgcca gcggacacgc
    22921 tcgcgatacc cgcgccgatc acccgtttgt tggttatggc ctgctgccaa tggaagtcca
    22981 cagcgagcag ggctgcgacg ttatttcccg tctgaaagtg cgtatcaacg aagtctatac
    23041 cgcgctgaat atgatcgatt acggtctgga taacctgccg ggcggcccgc tgatggtgga
    23101 aggctttacc tacattccgc accgtttcgc gctgggcttt gccgaagcgc cgcgcggcga
    23161 cgatatccac tggagcatga ccggcgacaa ccagaagctg taccgctggc gctgccgtgc
    23221 cgcgacctac gcgaactggc cgaccctgcg ctacatgctg cgtggcaata ccgtttccga
    23281 tgcgccgctg attatcggta gcctggaccc ttgctactcc tgtaccgacc gcatgaccgt
    23341 ggtcgatgta cgtaagaaga agagcaaagt ggtgccgtac aaagaactcg agcgctacag
    23401 cattgagcgt aaaaactcgc cgctgaaata aggaatcgcc atgtttacct ttatcaaaaa
    23461 agtcatcaaa accggcacgg cgacttcgtc ttatccgctg gagccgattg cggttgataa
    23521 aaacttccgt ggtaagccag agcagaaccc gcagcagtgc atcggctgtg cggcctgcgt
    23581 caatgcctgc ccgtcaaacg ccttaacggt tgaaactgac ctcgccacag gagagctggc
    23641 gtggcagttc aatcttggac gctgcatctt ctgtggacgc tgcgaagaag tctgcccgac
    23701 ggcggcgatt aagctgtcgc aagaatacga actggcggtg tggaagaaag aagacttcct
    23761 gcaacagtcc cgcttcgcgc tgtgcaactg ccgcgtctgc aatcgtcctt tcgccgtcca
    23821 gaaagagatc gactacgcca ttgcgctgct taagcacaac ggcgacagcc gcgcggaaaa
    23881 ccaccgcgaa agctttgaga cttgcccgga atgtaagcgc cagaaatgcc tggtgccgtc
    23941 cgaccgtatt gaactgactc gccatatgaa agaggccatc tgatgagcaa tttattaggc
    24001 ccccgtgacg ccaacggcat tccggtcccg atgacggtgg atgaatccat cgccagcatg
    24061 aaggcgtcgt tactgaaaaa aatcaaacgt tctgcctacg tttatcgcgt ggactgcggc
    24121 ggctgtaacg gttgcgaaat cgaaattttc gccacgcttt cgccgctgtt cgatgcagaa
    24181 cgcttcggca ttaaagtcgt tccgtcaccg cgtcatgcgg atattttact gtttaccggc
    24241 gcggtcaccc gtgcaatgcg atcccctgcg ctgcgtgcgt ggcagtccgc gccggacccg
    24301 aaaatctgta tctcttacgg tgcctgcggt aacagcggcg ggatcttcca cgatctctac
    24361 tgcgtgtggg gcggtacgga taaaatcgtt ccggtagatg tctacatccc tggctgcccg
    24421 ccaacgcctg ccgccacgct gtacggcttt gcgatggcgc tcggcctgct ggagcagaaa
    24481 atccacgccc gtgggccggg tgagcaagat gagcagccgg cagacattct acatcctgat
    24541 atggtgcaac cgttgcgtgt gaaagtggac cgtgaagcgc gtcgtctggc gggttatcgt
    24601 tacggtcgcc agattgccga tgatttcctg acacagttag ggcagggcga agaacaggtt
    24661 gcacgctggc tggaagcgga aaacgatccg cgtctgaacg agattgtcag ccatctgaat
    24721 catgttgttg aagaggcgcg tatccgatga gtgaaaaggt ggtgttcagt caactgagcc
    24781 gtaaatttat tgatgagaac gatgccacgc ccgccgaggc gcagcaggtg gtctattaca
    24841 gcctggcgat tggtcaccac cttggggtta tcgattgcct ggaagcggca cttacctgcc
    24901 cgtgggatga ctatctggca tggattgcca ctctggaggc gggcagcgaa gcccgccgta
    24961 aaatggaagg cgtgccgaaa tatggtgaga tcgtcatcga cattaaccat gtgccgatgc
    25021 tggccaacgc attcgataaa gcccgggcag cgcaaacttc gcagcagaag gaatggagta
    25081 caatgctgtt aagtatgctg catgatattc atcaggaaaa cgccatctat ttgatggtga
    25141 ggagactgcg tgactgacgt tttactttgt gttggcaata gcatgatggg cgatgatggc
    25201 gcaggcccgc tactggcgga aaagtgcgcc gccgcgccga aaggtaactg ggtagtgatt
    25261 gacggcggta gcgcaccgga aaacgacatt gtcgctatcc gcgaactgcg cccgacacgg
    25321 ctgctgattg tcgacgccac ggatatgggg ctaaaccctg gcgagatccg catcatcgac
    25381 ccggctgaca tcgccgagat gtttatgatg actacccata acatgccgct gaactatctt
    25441 atcgaccagt tgaaagaaga tattggcgaa gtgattttcc ttggcatcca gccggatatc
    25501 gtcggctttt actacccgat gactcagccg attaaagatg cggtggaaac ggtgtatcag
    25561 cggctggaag gctgggaagg aaatggcggc ttcgcgcagt tagcggtgga agaataattc
    25621 ttcattaggg aattcaggga attgaacatc aaaacaggga tgtgcgcttt tttattgagc
    25681 ttagtgctgc ctgcacaggc caccagcttt accgaatatc tgccaatgag tgacagcgaa
    25741 tacgcgcaaa agcgggcgct gaaacctctc ctgaccatgc cttatgatgc cgagcaaacc
    25801 tggcatttta gaaaagtggg cgtctgacac gttactacag agagaacaaa gaatgactgc
    25861 taatgctgca cgcgctgtta aagcaacaag agaactggtc aatgcagtcc cctttctggg
    25921 aggcagtgac tcagaagatg attaccgtga agcactggaa ctggtcgaat atttgattga
    25981 agaagatgat actaatccac ttatcgactt tctggcgagc cgcattgcag aatatgaaaa
    26041 caataacgaa aagtttgcag agttcgacaa agccgttgca gcaatgcctg ttggtgtggc
    26101 gttacttcgc acgctgattg atcaacataa tctgacctat gcagatttga agaacgaaat
    26161 cggctctaaa tccctggtca gccagatttt atctggacaa cgttccctga cgatatccca
    26221 cattaaggca ctttcagccc gatttggcgt taagccggaa tggtttcttt gactgatggc
    26281 agacgctaaa tcgcctgatg cgctacgcct atcgggcttt gaaagggcgc agattcttaa
    26341 ttttgcgcgc ccttgtttgt cattcaggct gttgtcttta ctactcttaa tttatcagta
    26401 agctcaatca gatatgcttt tgctttttcg cgtgctcgcc cctcgaaaag cattatccac
    26461 tcatgtgtgt cgtcgattgt ttgtaaacgg ccctggagtt ttttgctgaa agtcgacgtg
    26521 agctgataac cgtcgagttg atcaatttgt ttactcgatg tgattttttt cccggctgct
    26581 ttttgaatga taagttcaac gagaccgata acattattat cgtaattatc gtagagaaat
    26641 tcttcatctc cctgaaatcc gaacaaatct tcatgctggc ttaagcgttg aacaattgac
    26701 tcggcatcaa aggtcgaatc atcttgcagt tgttcctcta cccaattaat caaatccagc
    26761 ccttcgtcgc tttcgagagc ctccattccc catgaaccca ttttgtatcc ttacctgtta
    26821 tttcagtcga aatagtatta ttcaataaag gttcatcgct aatctgcgat gaacctcaaa
    26881 atacaatcat atggatagct gacaaagtgg tcgttgttca cgccgtatcc ggcacggttg
    26941 cttcccttaa atcctccccg ttactggcaa ttactttttt ataccaccag aacgacttgt
    27001 cggaaaaaag tacccagatg tggactggca acgataaaat attcattaga aaacggattc
    27061 tctctgcctt actacgataa atactgtcat cacatgtcat c
//
LOCUS       DAFGPF010000064        26597 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFGPF010000064 DAFGPF010000000
VERSION     DAFGPF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.064"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..3005
                     /locus_tag="LSX49_003000"
     CDS             <1..3005
                     /locus_tag="LSX49_003000"
                     /inference="COORDINATES: protein motif:HMM:NF025387.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hemagglutinin repeat-containing protein"
                     /protein_id="HBL7169385.1"
                     /translation="TQSQSASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSV
                     VVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAATMAREAKETSDSRLAALKGT
                     QAVLSGVQAGVNHGLQQQSADPNNGIGVSISLNHQQSKSETKYQHDIVSGSTLSAGNN
                     VSVTATGKNKDHNNSGDILITGSQIKSGNDTSLNAQNDILLTAAADTRQTTGKNSSKG
                     GGVGVSFGGGTNGGGLSIFAGINGSGGREKGNGTTWTETTLDAGKNVSLTSGHDTTLS
                     GAQVSGEKVTADVGNNLTISSLQDSDRYDSRQNSVAAGGSFTFGSMSGSGYASISQDK
                     IKSNYDSVREQSGIYAGKDGVDVTVGNHTQLNGAVIASTATDDKNSLNTNTLGWSDIH
                     NQADYKASHTGISLSGGSGMSASQMVASNAIAGAANALTGMSGSSGHAEGTTSSAISG
                     GNLIIRNKDSQKQDIAGLSRDPENANGSIAPIFDREKEQKRLQEAQVISQISGQMSNI
                     VMTYGETEAMKAARKEHPGMSDAQLRETPEYREVMKGYGTGSTPQMVVQAITGVLGGL
                     NAGNPGQVLAGGLNPAVAQLIKQATGDNREANLMAHAVWGALAAQLGGNNAASGAAGA
                     FSGELAARYIIDNYYCGRTDNLSEQERQQISMLVTIASGIAGGLAGNSTASVGTGAQA
                     GRNSVENNYLSVSEKTELEIAKQTLKNSKDPAEREKAQQKYDALLEKDISSDKAVIAA
                     CSNGQAASVACAGERLRVIAAKGGYETGNYNNQVSDMYPDAYGQIVNLLNITSVDAQN
                     QQQVKDAMVNYAMTQFGVDKATAESYVETYDGMKTVAASMTPVLGAAAANKISVLGQG
                     IVKESVSKNPNSSSAITDAEAGGYSYYDKFKNANGGWDWPKNLGFEGDPIKTIIPVGT
                     RLDRYGEPTGSFLAPKGTPYEQRALAPGTKAEKYYEYEVIKPLPAIQGKIAPAFGEPG
                     GGIQILPNMQERVNVEWLLKNGYIREVR"
     gene            3007..3417
                     /locus_tag="LSX49_003001"
     CDS             3007..3417
                     /locus_tag="LSX49_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 63 family protein"
                     /protein_id="HBL7169386.1"
                     /translation="MLLNINEIQKKIDALTLKAGLSRYSVNLCSAPIGDGTPYVTFEN
                     NVYNYIHSERGYEFSRKVTSSLDELLYWIMSELAYKIAFQYELEHRVEGRDGRRIAFP
                     KFIELMANMNLSWELKARHEIQKILTEAPYDDSL"
     gene            complement(4026..4343)
                     /locus_tag="LSX49_003002"
     CDS             complement(4026..4343)
                     /locus_tag="LSX49_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001039978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169387.1"
                     /translation="MTKPSTIAGTAGALATAGTAASTASTVAGASAATIMSATAGTTG
                     AALASVAGASGTAGAAAISSGMAAIGSTVGGGMAAGAVITAAAPVAISAAVIYGLVKI
                     FKD"
     gene            complement(4497..7610)
                     /locus_tag="LSX49_003003"
     CDS             complement(4497..7610)
                     /locus_tag="LSX49_003003"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HBL7169388.1"
                     /translation="MTDYNTIAESNNFIVLDKYIKAEQTSDSYQSESDLERELIQDLR
                     NQGYEFIPVKSQSAMLANVREQLQNLNGVVFNDSEWRRFTEQYLDNPSDGILDKTRKI
                     HIDYICDFIFDDERLENIYLIDKKNLMRNKVQIIQQFEQTGSHANRYDITILVNGLPL
                     VQIELKKRGVAIREAFNQIHRYSKESFNSENSLFKYLQLFVISNGTDTRYFANTTKRD
                     KNSFDFTMNWAKSDNTLIKDLKDFTATFFQKHTLLNVLVNYSVFDISQTLLVMRPYQI
                     AATERILWKINSSYKAKNWSTPESGGFIWHTTGSGKTLTSFKAARLATELDFIDKVFF
                     VVDRKDLDYQTMKEYQRFSPDSVNGSENTAGLKRNLDKDDNKIIVTTIQKLNNLMKAE
                     SDLPVYNQQVVFIFDECHRSQFGEAQKNLKKKFKRYYQFGFTGTPIFPENALGSETTA
                     SVFGRELHSYVITDAIRDEKVLKFKVDYNDVRPQFKSLETETDEKKLSAAENQQAFLH
                     PMRIQEITQYILNNFRQKTHRTYPGSRGFNAMLAVSSVDAAKAYYATFKRLQEEAANK
                     SATYKPLRVATIFSFAANEEQNAIGEISDETFDTSAMDSSAKEFLDAAIREYNNYFKT
                     NFSTDSSGFQNYYRDLAQRVKNQDIDLLIVVGMFLTGFDAPTLNTLFVDKNLRFHGLM
                     QAFSRTNRIYDATKTFGNIVTFRDLERSTIDAITLFGDKNTKNVVLEKSYTEYMEGFT
                     DAATGEAKRGFMAVVSELEQRFPDPASIESEKEKKYFVKLFGEYLRTENILQNYDEFA
                     TLKALQQIDLSDPVAVEQFKEEHYVDDEKFAELQTIRLPAERKIQDYRSAYNDIRDWQ
                     RREKEADKKEKSTTDWDDVVFEVDLLKSQEINLDYILGLIFEHNRQNKGKSEMTEEVK
                     RLIRSSLGNRAKEGLVVDFIQQTNLDDLPDKASIIDAFFTFAQREQQREAEALIKEEN
                     LNEEAAKRYIRTSLKREYATENGTELNETLPRLSPLNPQYKTKKQTVFQKINAFIEKF
                     KGVGGKI"
     gene            complement(7612..8856)
                     /locus_tag="LSX49_003004"
     CDS             complement(7612..8856)
                     /locus_tag="LSX49_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7169389.1"
                     /translation="MSQTLKQIAQELIDANKKVQLIYAFNGTGKTRLSREFKELIAPK
                     NINNPSCTEAEPSRNTILYYNAFTEDLFYWDNDLDTDAEPRLKIQPNTFTSWLIALLQ
                     TLGEDDNIITNFQRYTSSKATPIFNQEYSEVTFRISKSNPATPEISDKITEDDLTSVQ
                     GQYENIKISKGEESNFVWSVIYTLLEQVVSTLNELDATNRITDEFDKLEYVFIDDPVS
                     SLDDNHLIELAVDLAGLIKSSKSTLKFIITTHNPLFYNVLYNELSNKAYEKQANGEDI
                     LSYNAKREFKKYRLEKQADGLYQILEQKTDSPFSYHLFLLSEIQSAITDGQIRKYHFS
                     FIRNVLEKMATFLGYNYWPVLLPKTTDGKPDSFANRILNLSSHSAHAGEEIAVVDDVD
                     KEKLEELVNYLIQTYGFRKKEA"
     gene            complement(8858..10033)
                     /locus_tag="LSX49_003005"
     CDS             complement(8858..10033)
                     /locus_tag="LSX49_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL7169390.1"
                     /translation="MNETDRYLEKLLDGAEVQWEKLGDVLQRTKGTKITAGQMKALHK
                     DNAPLKIFAGGKTVAFVDFKDIPEKDINREPSIIVKSRGVIEFEYYDKPFSHKNEMWS
                     YHSNNDAISIKYIYYFLKTNEGYFQKIGSKMQMPQIATPDTDMFEIPIPCPDNPAKSL
                     AIQSEIVRILDKFSELTAELTAELTAELIMRKKQYNYYRDQLLSFKEDEVEWKTLGEV
                     AQFKRGTAITQKQTTPGEIPVVANGPIPTYFHNESNRQGETIVIARSGAYAGYVSFWN
                     RPIFLTDAFSVHPDLKIVKPKFIYHVLQNKQKHIHAMKKGAGVPHVRVKEFETYDIPI
                     PPITEQDRIVSILDKFDTLTNSITEGLPREIDLRQKQYEYYRNLLFSFQKSNVKEVA"
     gene            complement(10030..11586)
                     /locus_tag="LSX49_003006"
     CDS             complement(10030..11586)
                     /locus_tag="LSX49_003006"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL7169391.1"
                     /translation="MTSIQQRAELHRQIWQIANDVRGSVDGWDFKQYVLGALFYRFIS
                     ENFSSHMENGDDSICYAALDDGIITDDIKDDAIRTKGYFIYPSQLFCNVAAKANTNDR
                     LNADLNSIFVAIESSAYGYPSEADIKGLFADFDTTSNRLGNTVKDKNARLAAVLKGVE
                     GLKLGDFNEHQIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSKLIAQLAMHGQTHV
                     NKIYDPAAGSGSLLLQAKKQFDNHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFD
                     IRLGNTLTEPHFRDEKPFDAIVSNPPYSVKWTGSDDPTLINDERFAPAGVLAPKSKAD
                     FAFVLHALNYLSARGRAAIVCFPGIFYRGGAEQKIRQYLVDNNYVETVISLAPNLFFG
                     TTIAVNILVLSKHKTDTNVQFIDASELFKKETNNNILTNANIEQIMQVFASKEDVAHL
                     AKSVAFEAVVANDYNLSVSSYVEAKDNREIIDIAELNAELKTTVSKIDQLRKDIDAIV
                     AEVEGCGVQK"
     gene            11850..12722
                     /locus_tag="LSX49_003007"
     CDS             11850..12722
                     /locus_tag="LSX49_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HBL7169392.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVQRFRLSGHGHSMVITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGRELDTLVSALMTALP
                     DHAASPLMTRLQDELRTASVRSQAREQFTGAVDRIFDTAESVCIASVARTVLHAVRDT
                     VVSVARAVWNWIFF"
     gene            12940..15324
                     /locus_tag="LSX49_003008"
     CDS             12940..15324
                     /locus_tag="LSX49_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HBL7169393.1"
                     /translation="MHEKNIALLCDEADRLLQLNINLLRQMVDEPDVLSDSKNENRLL
                     FDKQKALKRIEELEGEQIKTARREMVLAVVGTMKAGKSTTINAIVGQEILPNRNRPMT
                     SVPTLIRHVPGKTEPVLHLEHIQPVRNLLSTLQEKLATPAGQQAAQTLQQTGDTCELL
                     DILANDGWLKNEYHGEEEIFTGLASLNDLVRLAAAMGSEFPFDEYAEVQKLPVIDVEF
                     SHLVGMDACQGTLTLLDTPGPNEAGQPQMEVMMRDQLQKASAVLAVMDYTQMNSKADE
                     DVRKELNAIADVSAGRLFVLVNKFDEKDRNGDGADTVRQKVPAMLNSDVLPASRVYPG
                     SSRQAYLANRALHELRKNGTLPVDEAWVDDFVREAFGRMKKDYVCKDSELATEGATDL
                     WEGSLIDQLITEVILSSHSRAAALAVDSAAAKLMQNAENVSEYLSLRHQGLQQSIQSL
                     QAHITSLLADIREIADCQEQVTTDVRMAMEEIDAKTRELLTGVCTSLEEELNDYFRSG
                     KRKEQQMLEEENSAQPRERNAFAFFHDIFGTGNQHDRMRDFDPDSPEIKFSDRREALE
                     LMTQIESTVTSLHREAEAQFRPELEKIVRGIETGFRGTALYATENIAGRINARLEDEG
                     FTVKISFPAVSQLQTRLAVKTNLSALMEERTETVTRRCRQDGVWGTLCRWANTSDWGW
                     KEYSVDVSRSVININKVREEVMSLTRTYFGELQASIEQDINQPVRQEIDAFFCTFREK
                     VEQLRNTLIQSSEDHKRDQQAQERLTGRLQALNERVPELITDSKALREELETML"
     gene            15321..16226
                     /locus_tag="LSX49_003009"
     CDS             15321..16226
                     /locus_tag="LSX49_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HBL7169394.1"
                     /translation="MTSPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAG
                     ERTFFRRLKEGMTGEGAARQNAINASLAQGVEASLRWLTELTTSLATTNYAITRVNDR
                     VSSLVSDTARLAHYSADTRGQLLTLADQVHQKLNHLEEKLHRVDQVQRAQLHLEQIFS
                     WWSAGRYASFSPAGRCYVALEELRWGAFGDVIRQGETGQVNQLLDILRHKALTQMAQE
                     SGGSATVRLNTLDWLGGQGREQADNEWHDAINWLGDWCSEEQHPVIWSTTQAAEHLPV
                     RMPRLCSAERLSESMVDEIFQKGAA"
     gene            16223..17293
                     /locus_tag="LSX49_003010"
     CDS             16223..17293
                     /locus_tag="LSX49_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL7169395.1"
                     /translation="MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGTQISMVSGASIG
                     AFNGAIIAASPDLSEAAVRLEALWDHLGNNQVLSVNRSVYFSLLKKLFQAMNLCQIPG
                     RAGALLTTLLHHISIINGFDNPMAQPLLSDEPLTALMDHYLDTDALADGLPLYVSLYP
                     TEGGMQDIIDCIRAELGAGTTKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQG
                     TMFCDGGMGGWRNMQGNTPVTPLVDAGCNMVIVTHLSDGSLWDRRAFPDTTILEIRPR
                     KRLKHTGEEGKSGGLLSFTSAHTDIWRQQGYEDTMLTMEHIRNPLAARQALTRSEAVL
                     QKSQDITEEADSALKNAMARIK"
     gene            17426..17968
                     /locus_tag="LSX49_003011"
     CDS             17426..17968
                     /locus_tag="LSX49_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001391476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169396.1"
                     /translation="MKFIVKALIYLAVMLSFTANAAEYKEYPQGEITYYKYLPKNGWT
                     LPAGYTVEQFSSAIYKGQIRNNFPWTNQFIVRGNGVLFLANKVNKTWHVLPVDYQKLN
                     FGRLTTHYQHVNKGDGCYFYILDGHGSDAKPILRIEENCVDMKMYRKMVAEKKEREQK
                     ANQWLQQQILAEHCRRYGNC"
     gene            18329..18811
                     /locus_tag="LSX49_003012"
     CDS             18329..18811
                     /locus_tag="LSX49_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001497177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169397.1"
                     /translation="MKRLHTLMLFLVFLFIGVSPDTNAATVNQTLKCGSKARAGQPGA
                     CPTTYELYEGDATYRAAIDKALNPVGLNGMFGEDGYMDGPDGGAYPVNINGTTWVEGG
                     GCKAHACGWDYIVTLYNPKTHKVVGYYYNIDPGYLIWFGETGVHEFAYLVRDYVNKTN
                     "
     gene            19179..20000
                     /locus_tag="LSX49_003013"
     CDS             19179..20000
                     /locus_tag="LSX49_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBL7169398.1"
                     /translation="MRLASRFGYAANQIRRDRPLTHEELMHHVPGIFGEDKHTSRSQN
                     YTYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRDGEINGQHVPEII
                     LLNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGDVVEKVIEGAYEVVGVF
                     DRIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLW
                     SAYQTIQENMLKGGISGRSARGKRIHTRAIHSIDTDIKLNRALWVMAETLLESMR"
     gene            20000..20245
                     /locus_tag="LSX49_003014"
     CDS             20000..20245
                     /locus_tag="LSX49_003014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169399.1"
                     /translation="MKHIPEGVIQVPESPDAPEALPGCRSISDDDLCAWCTRLLYRPG
                     ELSLCRLSTGNGIWPSVCDRNGYAYGCPEFQPNIIHP"
     gene            20339..20812
                     /locus_tag="LSX49_003015"
     CDS             20339..20812
                     /locus_tag="LSX49_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBL7169400.1"
                     /translation="MKTLSQNTTSSACAPETGLQQLVATIVPDEQRISFWPQHFGLIP
                     QWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRIID"
     gene            20828..21304
                     /locus_tag="LSX49_003016"
     CDS             20828..21304
                     /locus_tag="LSX49_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HBL7169401.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEHGLL"
     gene            21373..21594
                     /locus_tag="LSX49_003017"
     CDS             21373..21594
                     /locus_tag="LSX49_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBL7169402.1"
                     /translation="MKIITRGEAMRIHQQHPASRLFPFCTGKYRWHGSAGAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            21757..22134
                     /locus_tag="LSX49_003018"
     CDS             21757..22134
                     /locus_tag="LSX49_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HBL7169403.1"
                     /translation="MSDKLSGITHPDDNHDRPWWGLPCTVRPCFGARLVQEGNRLHYL
                     ADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTGGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPAAPAITV"
     gene            22181..22558
                     /locus_tag="LSX49_003019"
     CDS             22181..22558
                     /locus_tag="LSX49_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001757701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HBL7169404.1"
                     /translation="MNTLPDTHVREASGCPSPVTIWQTLLTRLLDQHYGLTLNDTLFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPEFSACTRSQLINSIDILRARRATG
                     LMTRDNYRTVNNITLGKYQEAKR"
     gene            22555..22983
                     /locus_tag="LSX49_003020"
                     /pseudo
     CDS             22555..22983
                     /locus_tag="LSX49_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708774.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22957..23874)
                     /locus_tag="LSX49_003021"
     CDS             complement(22957..23874)
                     /locus_tag="LSX49_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISEc35 family transposase"
                     /protein_id="HBL7169405.1"
                     /translation="MGKSKHKISNWKQYNQALVQRGSLTVWMDEQAIQQWHCQTHHGR
                     RGRGFHYSDSAIETALMLKAVFKLPLRALEGFINSLFELMNVPLQSPDYSCISKRAKT
                     VEIKYRLPSHGPVAHLVIDATGLKVYGEGEWKIRKHGKEKRRVWRKLHLAVDAATHAI
                     VAAEVSLETVGDNEVLPTLLNPLRRKIEQVSADGAYDTKACYALLQKKGAKATIPPRK
                     NAAFWKTDHPRNEAVAALKAGELEQWKKDSGYHQRSIAETAMYRFKQLIGPKLSLRSY
                     NAQVGEILAGVKVMNKVIGLGMPIRQAVN"
     gene            24123..24320
                     /locus_tag="LSX49_003022"
     CDS             24123..24320
                     /locus_tag="LSX49_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169406.1"
                     /translation="MKLLTTETALDILIARLQDNIDCESEIIFDNDEDKTDSAALLPC
                     IEQARQDVRTLRHLQFQHLNR"
     gene            24417..24977
                     /locus_tag="LSX49_003023"
                     /pseudo
     CDS             24417..24977
                     /locus_tag="LSX49_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708776.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            25049..26053
                     /locus_tag="LSX49_003024"
     CDS             25049..26053
                     /locus_tag="LSX49_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001179707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element ISSfl8 family transposase"
                     /protein_id="HBL7169407.1"
                     /translation="MQNITLIGIDLGKHSFHIHCQDKSGKALLRKKFTRTKLMQFLAT
                     CPPSVVVMEACAGAHFMARCISDFGHETKLISPQFVRPFVKSNKNDFVDAEAICEAAS
                     RPSMRFVQPRTETQQAMRALHRVRESLIRDKVKTTNQIHGFLLEFGISLPIGDAVIKR
                     LSLVLAEHEIPEYLSRLLVRLHTHYFYLVEQIAELESELSQSINADDTAQRIMTIPGV
                     GPITASLLSSQLGDGKQFSCSRDFAASTGLVPRQYSTGGKSTLLGISKRGDKNLRRLL
                     VQCARSFIMRLERKHGKLAEWVREQLNKKHSNVVTCALANKLARIAWAITTQKKEYQA
                     "
     gene            26335..26597
                     /locus_tag="LSX49_003025"
                     /pseudo
     CDS             26335..26597
                     /locus_tag="LSX49_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309436.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
BASE COUNT         6853 a         6343 c         6621 g         6780 t
ORIGIN      
        1 caacgcagag tcagagtgcc agcaccatcg gctccactgc cggtaatgtc agtattaccg
       61 cgggcaaaca ggctcatatc agcggttcgg atgtgattgc gaaccgggat atcagcatta
      121 ccggtgacag tgtggtggtt gacccggggc atgaccgtcg tactgtggac gaaaaatttg
      181 agcagaagaa aagtgggctg acggttgccc tttccggcac ggtgggcagt gccatcaata
      241 atgctgccac catggcccgg gaggcgaaag aaaccagcga cagccgtctg gcggcactga
      301 aaggaacaca ggcggttctg tccggtgtac aggccggtgt taaccacgga ctgcagcaac
      361 agagtgctga cccgaataat ggtatcggcg tgagcatttc gctcaaccat cagcagtcga
      421 agtctgagac gaaatatcag cacgatatcg tctccggctc aaccctcagc gccggtaaca
      481 atgtctccgt cactgccacg gggaaaaata aggaccataa caacagcggc gatattctca
      541 ttaccgggag ccagattaag tccggcaatg acaccagcct gaatgcacag aacgatattc
      601 tgctgactgc cgccgctgac acccgacaga ccaccgggaa gaacagcagc aaaggtggcg
      661 gtgtgggcgt cagctttggt ggtggaacca atggcggagg cctcagtatc ttcgccggta
      721 tcaatggttc agggggcagg gagaaaggca acggcacgac ctggaccgaa accacgctgg
      781 atgcgggtaa aaatgtctcc ctcacaagcg gacatgatac caccctgtcg ggggctcagg
      841 tcagtggcga gaaagtcact gcagatgtgg gtaataacct gaccatttcg agccttcagg
      901 acagcgaccg ttacgacagc agacaaaaca gcgtggccgc aggtggaagc ttcacgtttg
      961 gctcaatgtc cggcagcggc tatgccagca tcagtcagga caaaatcaaa agcaattacg
     1021 attctgtccg ggaacagagt ggtatctacg ccggaaaaga cggggttgat gtcactgtgg
     1081 ggaatcacac tcagctcaat ggtgcggtaa ttgcgtccac ggcaacggat gacaaaaaca
     1141 gcctcaatac caacacgctg ggctggtcgg atatccataa ccaggcagac tataaagcca
     1201 gccataccgg aatcagttta tcgggtggct cggggatgtc agccagccag atggtggcct
     1261 caaatgcaat agccggtgcg gcgaacgcac ttaccggtat gtccggcagc agtggacatg
     1321 ctgaaggtac cacgtcatcc gccatcagcg gcggaaatct cattatccgt aataaggata
     1381 gtcagaagca ggatattgcc gggctcagcc gggacccgga aaacgccaac ggcagcattg
     1441 caccgatatt tgacagggag aaagagcaga agcgtctgca ggaagcgcag gttatcagcc
     1501 agattagcgg tcagatgagt aacatcgtca tgacgtatgg cgaaactgaa gcgatgaaag
     1561 cagccaggaa agaacatcct ggcatgagcg atgcacagtt gcgggagacc ccggaataca
     1621 gagaggtcat gaaaggctac ggtacgggca gtacgccgca gatggtggta caggccatca
     1681 caggcgtgct gggtggactg aatgcaggga atccggggca ggtactggct ggcggtctga
     1741 atccggcagt ggcacagctt ataaaacagg ccaccggcga taaccgggaa gcaaacctga
     1801 tggctcacgc agtctgggga gcacttgccg cacaactggg cggaaacaat gcggcttccg
     1861 gtgctgcagg ggcattcagt ggtgaacttg ctgcccggta tatcattgat aactactact
     1921 gtggtcgcac tgacaatctg agtgaacagg aacgtcagca aatcagcatg ctggtcacca
     1981 ttgcctcagg gattgcgggc gggcttgccg gcaacagtac ggcgtctgtc ggtacggggg
     2041 cacaggcagg caggaactcg gttgagaata attatcttag cgtgtctgaa aagacagagc
     2101 ttgagatagc aaaacagacg cttaaaaaca gtaaagatcc ggcagagcgc gaaaaggcgc
     2161 agcagaaata tgatgcattg cttgaaaaag atatcagcag tgataaggcg gtaatcgctg
     2221 catgcagtaa tggacaggca gccagcgtgg cttgtgccgg tgaaagactg agggttattg
     2281 ctgctaaagg aggttatgaa accggaaact acaataacca agtcagcgat atgtatccgg
     2341 atgcttacgg gcagatagta aacctgctga atatcaccag tgttgatgca caaaatcagc
     2401 agcaggtgaa agatgcaatg gtaaactatg ctatgacgca gttcggtgtg gataaagcga
     2461 cggctgaaag ctacgtcgaa acctatgacg ggatgaagac tgtagcggca tcaatgacgc
     2521 cagtgttagg tgctgcggca gctaataaaa tcagtgtatt aggccaaggt atcgttaaag
     2581 aaagcgtatc taaaaaccct aactcttcaa gtgcaattac agatgctgaa gccggaggct
     2641 attcttacta cgacaaattc aagaatgcta atggtgggtg ggattggccc aagaatttgg
     2701 ggtttgaagg tgatccaatc aaaactataa ttccggtagg cacacgccta gatagatatg
     2761 gtgagcctac tggctctttc cttgctccta aaggtactcc ttacgaacaa cgagctctag
     2821 cgccaggaac taaagctgaa aaatactatg aatatgaggt aataaaacca ttgcctgcta
     2881 tacaaggaaa gattgccccc gcttttggtg agcctggagg ggggattcaa atattaccta
     2941 atatgcaaga acgagtgaat gtggaatggc tattaaagaa tggatatatt cgtgaggttc
     3001 gctaacatgt tgttgaatat caatgaaata caaaaaaaaa ttgacgcatt gactttgaaa
     3061 gctggtctct caagatattc agttaatctt tgttctgctc caattggtga tggcacacca
     3121 tatgttacat ttgaaaacaa tgtatataat tacattcatt cagaaagagg ttatgaattc
     3181 tcgcggaagg taactagttc gctagatgag ctactttatt ggatcatgtc agaactcgct
     3241 tataagatag catttcaata tgagttagaa cacagggtgg aaggcagaga tggacgacgt
     3301 atcgcgtttc caaaatttat tgagttaatg gcaaatatga atctttcatg ggagctaaaa
     3361 gcacgacatg aaattcaaaa gattctgact gaagcaccct acgacgatag tctttaaaag
     3421 tcatatgtca gagcaagtcg cgactaatac aaataaataa aaaatagtca tgcttacaat
     3481 aaaaaacacg gactaacctc tttacagtag ttagcccgtt attgatttaa ctaacgcacg
     3541 atattaatca aactattaaa attatccaca cacattgtaa attacatttt ttgcaaccaa
     3601 cgtaagcatc cggggaactc atattgacgc atttttcggg cacgtcgttg gcatataaac
     3661 gatcgccgtc tgacgatggt tgatttattc tgttgcgccg gggcgaccgc caggcaggta
     3721 ctggagtctg gttctgaagg actgagtctg gtgatcgtgt caggccgcga agtactgacc
     3781 acgggaatgg ctgccagctg attcaggttc tgacctgttg tcagcctgcg tggtgactgg
     3841 cctggctgat ttcctgtcgt caggcgttca actcccgact gcaggttatg gcccgctgca
     3901 cgaacacctg acggcagata tcactcaccc ggagaaggta aatccctcaa gaggcagcaa
     3961 ctctgccagt cgagctttcg gaaccgtcag gaggtgcgac tggtttctgt acgaagcccc
     4021 tgcaattaat ctttgaatat tttaaccagc ccataaatga cggctgcact aatcgcaaca
     4081 ggcgctgctg cagtaattac cgcaccggca gccatcccac caccaacagt ggaaccaatc
     4141 gctgccatac ctgatgaaat tgctgctgcg cctgctgtac cggatgcgcc tgcaacggaa
     4201 gccagagcag ctcctgttgt tcctgctgtc gctgacataa ttgttgcagc tgatgcacct
     4261 gcaacggttg atgctgttga ggctgcagta ccggcagttg ccaaagcgcc tgctgttccg
     4321 gctatagttg atggtttggt catcctgatt ttccttctgc aaattgagca agtaaagtaa
     4381 aattatttgt tgaataattt tacgacgatt tctttgccct ggtaaatatc ctttaataac
     4441 gttgctgaca ttttatctga gttggttggt tgagcaaacg gtcagtagtt gttccgctaa
     4501 atctttccac ccaccccctt aaacttctca ataaatgcgt taatcttctg aaaaaccgtc
     4561 tgtttttttg ttttatattg cggatttaaa gggctgagtc tgggcagtgt ctcgtttaat
     4621 tctgtgccat tttcggtagc gtattcgcgt tttaaagacg tgcgaatata gcgtttggcc
     4681 gcttcttcat tgagattttc ttctttgatc aacgcttctg cttcacgttg ttgttcgcgt
     4741 tgagcaaagg taaagaacgc gtcaatgata ctggccttat ccggcaaatc atccaggttc
     4801 gtttgctgaa taaaatcgac caccagacct tctttagcac ggttcccaag gcttgaacga
     4861 attaagcgtt tgacctcttc ggtcatttcg ctcttacctt tgttttgtct gttgtgctcg
     4921 aaaatcagac caaggatata atccaggttt atttcctgag acttcagcaa atcgacctca
     4981 aaaactacgt catcccagtc agtggttgat ttttcttttt tgtcagcttc tttctcacgc
     5041 cgctgccagt cacgaatatc gttataggca gaacgataat cctgaatctt gcgctcagca
     5101 gggagacgaa tcgtttgtaa ttcagcgaac ttttcatcat ccacataatg ttcttctttg
     5161 aattgttcta ccgcaacagg atcgctgaga tcgatttgtt gcagggcttt cagcgtggca
     5221 aattcatcat agttttgcag gatgttctcg gtacgtaggt attcaccaaa cagttttacg
     5281 aagtatttct tctctttttc actttcaata ctggcagggt cagggaaccg ttgttccagt
     5341 tctgaaacta ctgccataaa gccgcgctta gcttcaccag tggcagcatc agtaaagcct
     5401 tccatatact ctgtataact cttttctaac accacgtttt tggtgttttt gtcaccaaac
     5461 agcgttatgg catcaatagt tgagcgttcc agatcccgga aagtgacgat attaccgaag
     5521 gttttagtgg cgtcataaat gcggttggta cgggaaaatg cctgcatcag gccgtgaaaa
     5581 cgcaggtttt tatcgacgaa tagcgtgttc aatgttggag catcgaagcc ggttaaaaac
     5641 atccctacga caattaacaa atcaatatcc tgatttttaa cccgttgggc taaatcacga
     5701 tagtagttct gaaaaccgct actgtcggtg ctgaagttag ttttaaaata gttgttatac
     5761 tcacgaattg cagcgtcaag aaactcttta gcactgctgt ccattgcgct ggtatcaaaa
     5821 gtttcatcgg aaatttcacc aatggcattt tgttcttcat tggcggcaaa ggagaagatt
     5881 gtcgcaacac gcagtggttt ataggtagca gatttattag cggcttcctc ttgtaatcgt
     5941 ttaaacgtcg cgtaataggc tttcgcggca tccacgctgc ttactgccag catggcatta
     6001 aaacctctgg agccggggta agtacggtga gtcttctggc ggaagttgtt caggatatat
     6061 tgcgtgattt cctgaatacg catgggatga agaaacgcct gctgattttc agccgcactc
     6121 agttttttct cgtcagtttc tgtctctaaa gacttaaact gtggccgcac atcgttgtag
     6181 tccaccttga atttgagcac tttttcgtca cgaatcgcat cggtaattac atacgaatgc
     6241 aattcacgac caaatacgct ggcggtcgtt tctgagccta aggcgttttc cgggaaaata
     6301 ggtgtgccgg taaaaccaaa ctgataatag cgtttgaatt tcttcttcag atttttctgc
     6361 gcttctccaa actggctgcg gtgacattca tcaaatataa acaccacttg ctgattgtat
     6421 acaggcaggt cgctttctgc tttcatcagg ttattaagtt tctgaatagt ggtgacgata
     6481 attttgttat cgtccttatc cagatttcgt ttaagacctg ctgtattttc cgagccgttg
     6541 acgctgtctg gcgaaaaacg ctgatattcc ttcatagtct ggtaatcgag gtctttcctg
     6601 tcgaccacaa agaagacttt atcaataaag tccagttctg ttgccaggcg cgcggcttta
     6661 aagctggtca gggttttacc agaaccggtt gtgtgccaga taaagccacc gctttcgggg
     6721 gtagaccagt ttttcgcttt ataggagctg ttgattttcc ataagattcg ttcggtagct
     6781 gcaatctggt acggtcgcat caccagtagc gtctgactaa tatcgaacac gctgtagttc
     6841 accagaacat taagcagagt atgtttctgg aaaaaggtag cggtaaaatc tttgaggtct
     6901 ttaatcagcg tgttgtctga tttcgcccag ttcatggtga aatcaaaact gtttttatcg
     6961 cgctttgtgg tgttggcaaa ataacgggta tcggtgccgt tagaaatgac aaacagttgc
     7021 agatacttaa acagggaatt ttcgctgtta aaactctctt tactgtaacg atgtatctgg
     7081 ttaaaggcct cacgaatcgc cacgccgcgc tttttcagtt cgatttgtac cagtggtaag
     7141 ccattaacca ggatcgtgat gtcataacgg ttagcatgag accccgtctg ttcaaactgc
     7201 tggataatct gcaccttatt gcgcatgaga ttctttttat ctatcaaata gatgttctca
     7261 agacgctcgt catcaaaaat aaagtcgcaa atatagtcga tatggatttt acgggtctta
     7321 tccagaatgc catcgctcgg gttatccaga tactgctccg tgaaacgccg ccactcgctg
     7381 tcattaaaca ccacaccatt gaggttctga agctgttccc gaacgttggc cagcatcgcc
     7441 gactgtgatt ttacgggtat aaattcatag ccctgattcc gcaggtcctg aatcagttca
     7501 cgttccaggt ccgattcgct ctggtagctg tcgcttgttt gctcagcttt gatgtactta
     7561 tcaaggacga taaagttatt ggattcagca atagtattat aatcagtcat tttatgcttc
     7621 cttctttctg aaaccataag tttgaatcaa atagttaact aactcttcca atttttcttt
     7681 atctacatca tctacaacag ctatttcttc accagcatga gccgagtgac ttgataaatt
     7741 aaggattctg ttggcaaatg agtccggctt accatcagtt gttttaggta gcaatacggg
     7801 ccaatagtta taacctaaaa aagttgccat tttttccagt acgttccgga taaagctaaa
     7861 atgatatttc ctaatttgcc catctgttat ggcactttga atttcagata aaagaaatag
     7921 atggtatgag aatggtgagt ctgttttttg ctctaatatt tgataaagac catcagcctg
     7981 tttttctaag cgatattttt taaactccct tttcgcgtta taagatagaa tgtcttctcc
     8041 attagcttgt ttttcgtaag ccttattact caattcatta taaagaacat tataaaataa
     8101 tggattgtgt gttgtaatga taaatttgag tgtagacttg cttgatttta ttaaacctgc
     8161 taaatcaaca gctaactcaa ttagatggtt gtcatctaaa gaactcactg gatcatcaat
     8221 aaaaacatat tccaatttat caaattcatc tgttatgcgg ttcgttgcat caagctcatt
     8281 aagcgtagat actacctgct ctaataaagt gtatataaca ctccaaacaa aattgctctc
     8341 ttcgccttta gatattttta tattttcata ttgcccctga acggaagtta gatcatcttc
     8401 agttatttta tctgagattt caggcgttgc aggattgctt ttactaattc gaaaggtaac
     8461 ctcagaatat tcttggttaa atataggtgt agctttactg cttgtatagc gctgaaagtt
     8521 agtaatgata ttatcatcct cacctaatgt ttgcagtagt gcaataagcc aactggtaaa
     8581 tgtattaggc tggatcttta acctaggctc cgcatcagta tctaaatcgt tatcccaata
     8641 aaacaagtct tcggtaaacg cattgtaata aagaattgtg tttcgtgatg gctcagcctc
     8701 agtacagctt ggattattaa tgtttttagg ggcaataagc tctttaaact cacgtgatag
     8761 acgtgtttta cctgtaccat taaaagcata gattaattgc acttttttat tagcatcaat
     8821 tagttcttga gcaatctgct ttagtgtctg gctcatttca agcgacttcc tttacattag
     8881 atttttggaa actgaatagc aaattacggt agtattcgta ctgtttctgg cgcaagtcga
     8941 tttcacgcgg aagaccttcg gtgatggagt tggtcagggt gtcgaattta tcgagtatag
     9001 aaacgatacg gtcttgttcg gtgataggag gtataggtat atcataggtt tcaaactctt
     9061 taactcggac atgaggcaca cccgcacctt ttttcattgc atggatatgc ttttgtttat
     9121 tttgtagcac gtggtaaata aattttggtt ttacaatttt taagtcggga tgaacactaa
     9181 aggcatcggt taaaaatatt ggccgattcc agaaactgac atatcctgca taggcaccag
     9241 atctggctat aacgattgtt tcaccttgtc tgttgctctc attatgaaaa taagtaggaa
     9301 ttggtccatt ggcaactact ggtatttctc ctggtgttgt ctgtttttgg gtaattgctg
     9361 ttcctcgctt aaactgagcc acttccccca aagtcttcca ctcaacctca tcctctttaa
     9421 aactcaacaa ctggtcgcga tagtagttgt actgtttttt acgcatgata agctctgctg
     9481 taagctctgc tgtaagctct gctgtaagct cgctgaattt gtccagaatt cgcacgattt
     9541 cagactggat ggcaagggat tttgccggat tgtccggaca ggggattggg atttcaaaca
     9601 tatctgtatc aggagttgca atttgtggca tttgcatttt actcccaatt ttctggaaat
     9661 atccctcatt tgttttcagg aaataataaa tatactttat gcttattgca tcattattcg
     9721 agtggtatga ccacatctca tttttgtgag agaatggttt gtcgtaatac tcgaattcga
     9781 taacacctct ggatttgaca ataatcgatg gttctctatt aatatctttc tctggtatat
     9841 ctttaaaatc aacaaaggct actgtttttc ctcccgcaaa gattttaagc ggcgcattat
     9901 ctttgtgaag agctttcatc tgtccggcag ttatttttgt gcctttagtt cgctgaagca
     9961 cgtcccctag tttttcccac tgaacttcag ctccatccag caatttttcc agataacgat
    10021 ccgtttcgtt catttctgca ccccgcaacc ttcaacttct gccacaatcg catcaatatc
    10081 tttgcgtaac tggtcgattt tgctgaccgt ggttttcagt tccgcattca gctcagcaat
    10141 atcgataatt tcgcggttat ctttcgcttc cacatagctg ctcaccgaca ggttatagtc
    10201 attagcaaca acggcctcaa acgcgacaga tttcgccaga tgagcaacat cttccttgct
    10261 ggcaaatacc tgcataatct gttcgatatt ggcattggtc aggatattgt tgttagtctc
    10321 ttttttgaac aattcgctgg catcaataaa ctgaacgttg gtatccgttt tatgtttaga
    10381 cagaaccaga atgtttacgg caatggtggt gccaaagaac aggttcggtg ccagtgaaat
    10441 tacggtttcg acatagttat tatcgaccag atactgacgg attttctgct ctgcgccgcc
    10501 acggtaaaaa atacccggga agcagacaat cgcagcacgg cctctggcag aaagatagtt
    10561 cagcgcatgt aatacaaacg cgaagtctgc tttggatttg ggggccagaa cgccagccgg
    10621 ggcaaaacgt tcatcgttaa tcagtgtcgg gtcatcgctg ccagtccatt tcaccgaata
    10681 cggcgggtta gaaacgatgg catcaaacgg tttttcatct ctgaagtgtg gctcagtcag
    10741 tgtattaccc agcctgatat caaacttgtc gtagttgatg ttgtgcaaaa acatgttcat
    10801 acgtgccagg ttataggtcg tatggttgat ttcctgtccg aaaaagcctt cttcaatgat
    10861 atggttatca aactgctttt tagcctgcaa caacagcgaa ccggaacctg cggccgggtc
    10921 gtagattttg ttaacgtggg tctgcccgtg catagccagt tgtgcaatca gcttagagac
    10981 gtgctgcggt gtaaagaact cgccgccgga cttaccagca ttcgccgcat agttagaaat
    11041 caggaactca taggcatcgc cgaacaggtc aatctgatgt tcgttaaagt cgccaagctt
    11101 taacccttca acccctttca gaaccgctgc caggcgggca tttttatcct taacggtgtt
    11161 acccaggcgg ttactggtgg tatcgaaatc agcaaacaaa cctttgatgt cagcttctga
    11221 agggtaaccg taagcagagc tttcgatagc aacgaagata ctgtttaaat ctgcattcag
    11281 tctgtcattg gtatttgctt tcgccgctac gttgcagaaa agctgactgg ggtagatgaa
    11341 gtagcctttg gttctgatgg catcgtcttt aatgtcatca gtaataatgc cgtcatcaag
    11401 tgccgcataa cagatgctgt catcaccatt ttccatatgg ctggaaaaat tttcgctgat
    11461 aaaacggtag aaaagtgcgc ccagaacgta ttgcttaaaa tcccatccat caacagaacc
    11521 tctgacatca ttggcaattt gccatatctg gcggtgcagt tctgctcgtt gttgaatact
    11581 tgtcattttt aatccatttt cctggtttgg acctgaatca ttgggggcaa ttctacagca
    11641 atcttgtggt tcaggcagcc ccggagtaag tcggtcgaca ttgtgagata cctggggtat
    11701 tcacgataag gaggaggaac ggaatactgc ctttcctttg cagtgcacca ggtacattct
    11761 aaataatttc agacagatat tatctccgtg gttcccccgc ctcctttccg gtgtgcgggt
    11821 ttttgtcttt tttcaccggg aatacatgta tgaatccgtc tgatgccatt gaggcaattg
    11881 aaaaaccgct ctcctccctg ccttactcac tttcccgtca catcctggaa catctgcgca
    11941 aactcaccag tcacgaaccc gtgattggca ttatgggtaa aagcggggcc ggtaaatcct
    12001 cactctgtaa tgccctgttt cagggggagg tcacaccggt cagtgatgtt cacgccggca
    12061 cccgggaagt gcagcgcttc cgtctgagtg gtcacggtca cagcatggtt atcactgacc
    12121 tgcccggggt gggcgagagc cgggacaggg atgcagagta tgaagccctg taccgtgaca
    12181 ttctgccgga actggacctg gtactgtggc tgattaaagc cgatgaccgg gccctgtctg
    12241 tggatgagta tttctggcga cacatcctgc accggggaca tcagcaggtg ctgtttgtgg
    12301 tgacgcaggc cgacaaaacg gagccctgcc atgaatggga tatggccggc attcagcctt
    12361 ctcccgcaca ggcacagaat attcgcgaaa aaacggaggc ggtattccgt ctgttccggc
    12421 ccgtacatcc ggttgtggcc gtatcggccc gcaccggccg ggaactggat acgctggtca
    12481 gtgcgctcat gacagcgctt cccgaccatg ccgccagtcc cctgatgacc cgcctgcagg
    12541 acgagctgcg cacggcgtct gtccggtctc aggcccgtga acagtttacc ggtgcggtgg
    12601 accggatatt tgacacggcg gagagcgtct gtattgcctc tgttgcacgc acggttctgc
    12661 atgccgtccg tgacaccgtg gtctctgttg cccgcgcggt atggaactgg attttcttct
    12721 gaacccggtg gtgatgtacc aggctgttgt tacagatttt taaccccatg aaaacactat
    12781 gcaaacgcag ccatacccgg gttgtcccct tgcgttgtgt ctcccagatt aatagaatac
    12841 atcgatcgtt actattatat cgatcgttat aaacgatcat ttgtggtaaa tgacctcctc
    12901 cgtggttgtc atgaaaatgc gtctcaggaa ggttaaataa tgcacgaaaa gaacatcgct
    12961 ctgctttgtg atgaagccga ccgacttttg caactgaaca ttaatctgct ccggcaaatg
    13021 gttgatgaac cggatgtgtt atctgacagt aagaacgaaa acagactgct tttcgataaa
    13081 cagaaagcac tgaaaagaat tgaggagctg gagggcgaac aaatcaaaac cgcccgcagg
    13141 gagatggtgc tggctgttgt cggcacgatg aaagcaggta aatcaaccac catcaacgcc
    13201 attgtggggc aggaaattct gcctaaccgt aaccgcccca tgacctctgt accgacgctc
    13261 atccgccacg ttcccggaaa aactgagccg gtcctccatc tggaacatat tcagcccgtc
    13321 cgcaatttat taagcacact gcaggaaaaa ctcgccaccc cggcaggaca gcaagccgca
    13381 cagaccctgc agcaaaccgg ggatacctgc gaactgctgg atattctggc aaatgatggc
    13441 tggctcaaaa atgaatacca cggggaggag gaaatcttta ccggactggc atcgttaaac
    13501 gatctggttc gtcttgctgc ggcaatgggg agtgagtttc cttttgatga atacgccgaa
    13561 gtgcagaaac tgccggtgat cgacgtggaa ttcagccatc tggtggggat ggatgcatgc
    13621 cagggaacac tcacactgct ggatacccct ggccctaatg aggccggaca accgcagatg
    13681 gaagtgatga tgcgggatca actgcagaaa gcctctgcgg ttctggctgt gatggattac
    13741 acccagatga actcaaaagc ggatgaagac gtccgtaaag agcttaatgc cattgctgac
    13801 gtatcagccg gccgcctgtt tgtgctggtc aataaatttg atgagaaaga ccgcaatggc
    13861 gatggggcag atactgtacg ccagaaggta ccggcaatgc tgaacagcga tgtgctgccc
    13921 gcctcccgcg tttatccagg ctcatcacgt caggcgtacc tggctaaccg tgcgcttcat
    13981 gagttacgga aaaacggaac ccttcctgtt gatgaagcct gggtcgatga ttttgtcagg
    14041 gaagccttcg gtcgcatgaa aaaagattac gtctgtaaag acagcgaact ggcaaccgaa
    14101 ggggcgacag acctgtggga aggctcactt atcgatcaac tgataacgga agtcatactg
    14161 agttcacatt ccagagctgc ggcactggcg gttgattctg ccgccgcaaa actgatgcag
    14221 aatgcggaaa atgtcagcga atatctgtca ttacgccatc aggggctaca gcaaagcatt
    14281 cagtcactgc aggcgcatat caccagcctg ctggcggata tccgggaaat cgcggactgt
    14341 caggagcagg tgaccactga tgtcagaatg gctatggagg agattgatgc taaaacccgg
    14401 gaattactga cgggggtctg cacctcactg gaagaggagc tgaatgacta tttcagaagc
    14461 ggtaaacgca aagaacagca aatgctggag gaagaaaatt cagcgcagcc ccgggagaga
    14521 aacgcattcg ctttctttca cgatattttc ggaaccggaa atcagcatga caggatgcgg
    14581 gactttgatc cggacagccc cgaaataaaa ttcagtgatc gcagggaagc ccttgaactg
    14641 atgacgcaaa tcgaatcgac cgtgaccagc ctgcaccgtg aggctgaagc acagttccgt
    14701 cctgaactgg aaaaaatcgt caggggtatt gaaacaggtt ttcgtggtac ggccctgtac
    14761 gccacagaaa atattgccgg acgcatcaat gcccgtctgg aggatgaagg tttcactgta
    14821 aaaatcagtt ttccggcagt cagccagtta cagacccggc tcgcagtaaa aacaaatctg
    14881 agtgcgctta tggaggaaag aacggagacc gtcacccgtc gctgtcgaca ggatggtgtc
    14941 tggggtacgc tttgtcgatg ggcaaacacc agtgactggg gctggaaaga gtacagtgtg
    15001 gatgtgagcc gcagcgtgat caatatcaac aaggtcagag aggaagtgat gtcactgacc
    15061 cggacatatt tcggggagct gcaggcatcc attgagcagg atattaacca gcccgtccgc
    15121 caggaaatcg atgccttttt ctgtacattc agggagaaag ttgaacagct gcgtaacacg
    15181 ctgattcaga gctctgaaga tcataaacgc gatcagcagg cgcaggaacg gctgaccggg
    15241 cgtcttcagg cgttaaatga aagggttcct gagctcatta ctgacagtaa ggcgttaagg
    15301 gaagaactgg agacaatgct gtgacttcac catttattca acaaattgct gataaccggg
    15361 tatgtcaggt actcacctgt cttcctgaaa aatttgtggt tgatttcgca aacggaatcg
    15421 atgttgcaca ggagcatatc cgcacggccg gagagcgcac gttcttccgg cgtttaaaag
    15481 aggggatgac cggcgaaggc gctgcacggc agaatgccat caatgcttcg cttgcacagg
    15541 gcgttgaggc gtccctgcgc tggctgacgg agctgacaac gtcacttgcc accacaaact
    15601 acgcgattac ccgggtaaac gacagggtca gttcactggt cagtgatact gccaggctgg
    15661 cgcattattc cgcagatacg cgggggcagt tactcaccct ggccgatcag gttcaccaga
    15721 aactgaatca tcttgaagaa aaactccacc gtgttgacca ggttcagcgg gcgcagttac
    15781 atcttgagca gatattctca tggtggagcg ccggacgata tgcgtcattt tcccctgccg
    15841 gacgttgtta tgtggcactt gaagagcttc gctggggcgc gtttggtgat gtgatacgtc
    15901 agggcgaaac aggccaggtt aaccagctac tggatattct cagacataaa gcattaacgc
    15961 agatggcaca ggagagtggc ggtagtgcaa ccgtgcgtct gaacactctg gactggcttg
    16021 gtggtcaggg ccgggagcag gcagataacg agtggcatga cgcgattaac tggctggggg
    16081 actggtgcag tgaagagcag catccggtga tctggtcaac cacgcaggct gcagaacact
    16141 taccggttcg catgccccgt ctctgctctg cagaacgcct ctctgaaagt atggtcgatg
    16201 aaatatttca gaagggggct gcatgagtac agaaatgaaa acggggctgg tgctgtccgg
    16261 cggcggggcg gtgggtgctt atcaggcggg agtggttaag gcactggcag agtgtggtac
    16321 acagatcagc atggtttcag gggccagcat tggcgcattc aatggtgcta ttatcgcggc
    16381 ctctcccgat ctgtcagaag ctgccgtacg cctggaggcg ctctgggatc atctggggaa
    16441 taatcaggtg ctgtcggtaa accgatcggt ttacttttca ttgctgaaaa aattgttcca
    16501 ggcaatgaac ctctgccaga tccccggacg tgcaggagca ctgcttacga cacttcttca
    16561 ccatatatcg ataatcaacg gcttcgacaa tccgatggct cagccgctgt tgtcagatga
    16621 gcctctgaca gcgctgatgg atcattatct cgatactgat gctctggcag acgggctacc
    16681 gctgtatgtg tcgctgtacc ccacagaagg gggcatgcag gatattattg actgcattcg
    16741 tgctgaactg ggtgccggaa ccacgaaaaa cgccgttttt cagcatatcc agagtctgcc
    16801 ccgcggacag cagaaagagg ctctgcttgc gtcagccgca ctgcccctgt tgttccgtcc
    16861 ccgtgaggtt caggggacaa tgttctgtga tggtggtatg ggaggatggc gaaatatgca
    16921 gggaaatacc cctgtaacac ctctggtcga tgccggatgc aatatggtga ttgtgacgca
    16981 tctgagtgac ggttctttat gggatcgccg ggcttttccg gacaccacaa tccttgaaat
    17041 ccgtccccgg aaaaggctga aacacacagg ggaagaaggc aaaagtggcg gtctgctcag
    17101 ttttacatcg gcacataccg acatctggcg tcagcagggc tatgaagaca cgatgctgac
    17161 gatggagcat atccggaacc ccctggcggc gcgtcaggca ctgacccggt cagaggcggt
    17221 attgcagaaa agccaggata taacggaaga ggcagattcg gcactgaaaa acgcgatggc
    17281 ccggattaaa taaagacgcc ccaaagaaac gccaccgcct gtggtggtgt ttttcttggc
    17341 tggtgttatt gaaaatattt tcagatatat gttacccggg tgagatttaa tattgacgca
    17401 tttattactg tcataaggag ttatcatgaa attcatcgta aaagcactta tttatcttgc
    17461 tgtcatgtta tcattcacag ccaatgctgc tgaatataaa gaatatccac aaggagaaat
    17521 tacctattac aaataccttc ccaagaacgg ctggacactg cctgcaggct ataccgtaga
    17581 acaattttcc agtgccattt acaaagggca aatacggaat aacttcccct ggacaaatca
    17641 gttcatcgtg cgtgggaatg gggtactttt cctggccaac aaagtcaata aaacctggca
    17701 tgttcttccg gtggattatc agaaattaaa cttcgggaga ttgacgaccc attatcaaca
    17761 tgtaaacaaa ggcgacggtt gttactttta catcctcgat ggccatggtt cagatgcaaa
    17821 accaatttta agaattgaag aaaactgcgt tgacatgaaa atgtacagga aaatggttgc
    17881 agagaaaaag gaacgcgaac aaaaagcgaa ccaatggctc cagcagcaga ttcttgcaga
    17941 acattgccgt cgctacggta actgctaata acaccggtaa gtaaaaaaga gggttctggt
    18001 ttccagatta ttttaaaagc attttatacc atcgttattt tctgtgctgt tggtatcagc
    18061 atatttacac tttcggcgag ccggatattc actattacaa cccggctctg tattcatcca
    18121 taatcaatcc tgatgaagtc cctgtactaa tgcgcatgtt tatcaacaac tcaatgatat
    18181 tgtctgcggg caaccgaagg taatatccgt cagtatccat ccattagcgg tcggtaatta
    18241 taccgctgtg gacttctttc acagcgctga attaatcggt cgtattacct taaatcgcag
    18301 tgctgaataa cttaacaagg aatttataat gaaacgttta catactctga tgctctttct
    18361 ggttttcctg tttattggtg taagtcctga cacaaacgcc gccactgtaa atcagacact
    18421 taaatgcggc tcaaaagccc gggctggcca gcctggtgca tgtccaacaa cgtacgagtt
    18481 atacgaaggt gacgctacct acagagctgc tatcgacaaa gcattaaacc ctgttgggtt
    18541 aaacggaatg tttggggaag acggctatat ggatggtcct gatggtggtg cgtatcctgt
    18601 aaacattaac ggaacgacct gggtagaagg tggcggttgt aaagcccacg cctgcggctg
    18661 ggactatatc gtaacactct ataacccaaa aacgcataaa gtcgttggtt actattacaa
    18721 catcgaccct ggttacctga tttggtttgg tgaaactggc gttcacgaat tcgcgtacct
    18781 ggtcagggac tacgtaaaca aaacaaatta aaggcgtaag ttatgtgatt catctgcgcg
    18841 ttattaatat caaaagtaaa tacggcccca gccatgatgg cagggctttt taatttcagg
    18901 gagcaacaga tatgtcaggt tgtacttcac gtttattccc tgagggacct tttgctgcca
    18961 aatggcatct gaatcgatca cagtctggcc ggttattacc cgatcccgat gggattattg
    19021 ggtgatctcc ttccataaaa atatgcagct cgccagtgac gggcttctca gacaataaac
    19081 ctcattaatt tcgtccatca ggccgcgtct tctccgggag acgcggcttt tttcatttat
    19141 tacaccagta aatcttaact accgataagg agcaaagtat gcgattagcc agtcgttttg
    19201 gttatgctgc aaaccagata cgccgtgacc gtccgctgac acatgaagag ctgatgcacc
    19261 atgtgccggg gattttcgga gaagataaac acacgtcccg aagccagaac tatacgtaca
    19321 tccccaccat caccgtgctg gaaagcctgc agcgggaagg cttccagcca ttcttcgcct
    19381 gccagacccg cgtgcgcgac ccgggccgcc ggggatacac caaacacatg ctgcgtctgc
    19441 ggcgtgacgg ggagataaac ggacaacatg tccctgaaat catcctgctg aactcccatg
    19501 acggtacctc cagctaccag atgctgccgg gttacttcag gttcgtctgc cagaacggat
    19561 gcgtctgtgg tcagtctctg ggggaagtgc gtgttccaca ccggggagac gtagtggaga
    19621 aagttatcga aggggcttac gaggtggtgg gggtttttga ccggatagag gagaagcgtg
    19681 atgccatgca gtcgctggtc ctgccgccac cggcacgcca ggcgctggca caggcggcac
    19741 tgacttaccg ttatggtgac gaacatcagc ccgtcaccac cgccgacatt ctgacaccgc
    19801 gacgccggga ggattacggt aaggacctgt ggagtgctta tcagaccatc caggagaata
    19861 tgctgaaagg ggggatttcc gggcgcagtg ccagaggaaa acgtatccat acccgtgcca
    19921 ttcacagcat cgacaccgat attaagctca accgcgcatt gtgggtaatg gcagaaacgc
    19981 tgctggagag tatgcgctga tgaaacatat ccctgaaggc gtgattcagg taccagaatc
    20041 acctgacgcc ccggaagcgc tgccggggtg tcgttccatt tctgatgatg acctgtgcgc
    20101 ctggtgtacc cgtctgcttt accgtcccgg agaactcagt ctgtgcagac tgagtacagg
    20161 caatggcatc tggccatccg tctgtgaccg gaacggttac gcgtacggct gtccggagtt
    20221 tcagccgaat atcattcatc cctgacatta ccgggtctca cggtcagtga tgaacgtgat
    20281 gttgtcagcc cccggccttt actccctctc atttattcac attacaagga tttcatacat
    20341 gaaaacattg tctcagaaca ccacctcttc agcctgtgca ccggagactg gcctgcaaca
    20401 actggttgcc accatagtcc ctgatgaaca gcgcatcagc ttctggccgc agcattttgg
    20461 cctcattcca cagtgggtga ccctggagcc ccgtgtcttc ggctggatgg accgtctgtg
    20521 cgaagactac tgcgggggca tctggaatct gtacaccctg aacaacggtg gcgcatttat
    20581 ggcacctgaa ccggatgacg atgatgacga gacatgggta ctgttcaatg ccatgaacgg
    20641 taaccgcgct gaaatgagcc cggaagccgc cggcattgct gcctgtctga tgacgtacag
    20701 tcatcatgcc tgtcgtacgg agtgttatgc catgacggtc cattattacc ggctgcggga
    20761 ttacgccctg cagcatccgg aatgcagcgc cattatgcgc atcattgact gaatggaggc
    20821 agggacaatg cagcagcttt cctttctgcc cggagagatg acgcccggcg agcgcagcct
    20881 cattcaacgg gccctgaaaa ccctggaccg ccatcttcat gaacccggcg tggccttcac
    20941 ctccacccgt gcggcacgag aatggctgat tctgaacatg gcgggactgg agcgtgaaga
    21001 attccgggtg ctgtatctga ataaccagaa tcagctgatt gccggtgaaa ccctcttcac
    21061 cggcaccatc aaccgcacgg aagtccatcc ccgggaagtg attaaacgcg ccctgtacca
    21121 caatgccgca gccgtggtgc tggcacacaa tcacccgtcc ggtgaagtca cacccagtaa
    21181 ggcagaccgc cttatcaccg aacgtctggt acaggcactg ggcctggtgg atatccgggt
    21241 gccggaccat ctgatagtcg gtggcagcca ggttttctcc tttgccgaac acggtctgct
    21301 ttaacccgtc accgtcacaa ccacatcaca cctgttttca cttttatctt ctgtcttcag
    21361 aggtatcaca ctatgaaaat catcacccgt ggtgaagcca tgcgtattca ccaacaacat
    21421 ccggcatccc gtctttttcc gttctgtacc ggcaaatacc gctggcacgg cagtgccggg
    21481 gcgtatacag gtcgtgaagt acaggatatt cctggtgtgc tggccgtgtt tgctgaacgc
    21541 cgtaaggaca gttttggccc gtatgtccgg ctgatgagcg tcaccctgaa ctgatgttcc
    21601 gtcacccgga aaacgagtac gaccagatgg actcagacgc cgctgtggat gaggccattc
    21661 tcgtcaatgc atacatcttc accgaaaccg gtcagcgcgc cggctgacct gtcatcgtta
    21721 aaccattctt aaccactttt cagagaggat tttatcgtgt cagacaaact ctccgggata
    21781 actcatcccg acgacaatca cgaccgcccc tggtgggggc ttccctgcac agtgaggccc
    21841 tgttttggtg cccgtctggt gcaggagggt aaccgcctgc attaccttgc cgaccgcgca
    21901 ggtatcagag gccgcttcag cgacgcagat gcataccatc tggaccaggc ctttccgctg
    21961 ctgatgaaac aactggaact catgctcacc ggcggtgaac tgaatccccg ccatcagcat
    22021 accgtcacac tgtatgcgaa agggctgacc tgtgaagccg atacccttgg cagttgtggt
    22081 tacgtttatc tggctgttta tccgacaccg gcagcgcccg caatcaccgt ataaccccgg
    22141 atatctcccc tttatcacca cctgttacag agaacttaag atgaatacat tacccgacac
    22201 tcacgtacgg gaggcatcgg gctgcccgtc tcccgtcacc atctggcaga cactgctcac
    22261 ccgactgctg gaccagcact atggcctcac gctgaatgac acactgttcg ctgatgaacg
    22321 tgtgattgag cagcatattg aggcagggat ttcactgtgt gacgcggtga actttcttgt
    22381 tgaaaaatac gcgctggtgc gtaccgacca gccggaattc agtgcctgta cccgctctca
    22441 gttaataaac agcatcgata tcctccgggc tcgccgggcg actggcctga tgacccgcga
    22501 caattaccga acggtaaata acattaccct gggtaagtat caggaggcga aacgatgaaa
    22561 ctggccctga cgctggaagc tgacagcgtt aacgtgcagg cactgaacat ggggcgcatt
    22621 gtcgttgacg tcgatggtgt taatctcact gaactgatta ataacgtcgc tgaaaacggt
    22681 tattcactcc gtgtggtgga ggaatccgac caacagtcaa cctgcacacc tccgccattt
    22741 gcaacccttg ccggcatacg ctgcagtacc gcacatatca cggaaacgga caacgcctgg
    22801 ttgtactcgc tgtcacacca gaccagtgac gttggtgaat cagaatggat tcatttcaca
    22861 ggtagcggct atctgttacg taccgatgcg tggtcatacc ggccttgttg atcaaatcca
    22921 aagttggatg gtcgctcccc aacccgccgg gcgggcttag ttgacagcct gccgaatagg
    22981 cataccaagc cctatgacct tgttcatgac tttcaccccg gccaggatct cacccacctg
    23041 ggcgttgtag ctccgcagac tcagtttcgg accgatgagc tgcttgaagc gatacatggc
    23101 ggtctcagct atcgagcgct gatgatagcc agagtccttt ttccattgct ccagttctcc
    23161 tgccttgagc gcggcaaccg cctcgttgcg tggatggtct gtcttccaga atgccgcatt
    23221 ttttctcggc ggtatggtgg ccttggcgcc cttcttttgt agtagggcat aacaggcttt
    23281 ggtgtcatag gcaccatcgg cgctgacttg ttctatcttg cggcgcaagg ggttgagcag
    23341 cgtgggcaac acctcgttat cgcccaccgt ttccaggctg acttcggctg caacgatggc
    23401 atgggtcgcc gcatctacgg caaggtgaag cttgcgccag acgcggcgtt tctccttgcc
    23461 gtgcttgcga attttccatt cgccttcgcc atagaccttg agtccggtgg catcgatgac
    23521 caggtgagcc actgggccat ggctcggtag gcggtacttg atttcgaccg tcttggcgcg
    23581 cttgctgata cagctgtagt ccggcgactg taagggcaca ttcatcagct cgaacagcga
    23641 gttgatgaag ccttccaagg cacgcagcgg tagcttgaat accgccttga gcatcagcgc
    23701 ggtttcaatg gcggagtcgc tgtaatggaa gcctcgccct cggcggccat gatgggtctg
    23761 gcaatgccac tgctggatgg cttgctcatc catccagacg gtcaacgaac cacgttgcac
    23821 caaggcttgg ttgtactgtt tccagttgct gatcttgtgc ttggacttgc ccatctggcg
    23881 ctcccggtgg tgaacctaag agatcagatc accaaactgc gggatagttc cctgatttga
    23941 gcaacaacgc cggtcatacc cggttctgcg gcttaagcgc ctgggcctgt caaaaacgtt
    24001 ccgtcgtctg gttgtcacac tcacccggcg ttatggcgtc agtctcattc atctggacgc
    24061 cagcgcagaa tgtctgccgg ggttccccac tttcgactgg taatcaggac aaaagacact
    24121 ggatgaaatt attaaccaca gaaacggcgc tggatattct gattgcgcgg ctgcaggaca
    24181 atattgactg cgaatcggaa attatctttg acaacgatga ggataaaacg gattcggcag
    24241 cactgttgcc ctgtatcgaa caggcgcgac aggatgtccg aactctgcgc catctgcagt
    24301 ttcagcacct gaaccggtga gtttcactca ttatctttct caccacactt cattcccccg
    24361 acgccagcct gaatacggct ggcgttttca tttataaaca gaaaggaaaa ccgattatgt
    24421 caggcatcac aatcgcccgt ccggaagtgg tcaacgggca tacggacgtt atctgctcaa
    24481 ccagtatccg ccacattctg gctgtacgaa agagtacact gctgcaaatc gacacactta
    24541 tccggcaact ggctgaaata tcagcaatga cagaaagtat tggcggtaaa accgcactgg
    24601 actgggcaat gaaacaggat tttcgctgcg gttgctggct gatggaaaaa cctgaaacgg
    24661 caatgaaagc catcacccgc aatctcgatc gagaaatctg gcgtgacctg atgcaacatt
    24721 cagggatgct ttccttaatg gatgcccagg accgtgatac atggtaccgg tcactggagt
    24781 acgataattt tccggaaatc agtgaagcga acattctgag cacatttgaa caactgcacc
    24841 agaataagga tgaggtgttt gagcgagggg tgatcaacgt cttcagggga ctgagctggg
    24901 attacaaaac caactcaccc tgtaaatttg gcagtaaaat tatcgtcaac aatctggtga
    24961 ggtgggaccg gtggggataa tgatatggtc acccccacct taacagcagt acgctgttaa
    25021 ggtaaatccc tttaacggag agaccatcat gcagaacatc acacttattg gtatcgatct
    25081 cggaaagcac tccttccaca ttcattgtca agacaagtct ggtaaggctc ttctgcgtaa
    25141 aaaatttacc cgtactaaac tgatgcagtt tctggcgaca tgtccgccct cagttgttgt
    25201 aatggaagcc tgtgcgggtg cacactttat ggctcgctgt atctctgatt ttgggcatga
    25261 aactaagctg atttctccac agttcgttcg cccgtttgtc aaaagtaata agaatgattt
    25321 tgttgatgca gaagccatat gcgaagcggc ttcacgacca tcaatgcgtt ttgtccagcc
    25381 aagaactgag acccagcagg ccatgagggc gttacaccgg gtcagagaat cgctcatcag
    25441 agataaggtg aaaacaacca accagatcca cggtttcttg ctggaatttg gaatcagcct
    25501 gccgataggt gatgctgtaa taaaacggtt gtctctcgtg ttggctgaac acgaaatccc
    25561 cgaatatctg agccgccttt tggtgaggtt gcatacccac tacttttacc ttgttgagca
    25621 aatagcagag ctggaatcag aattaagtca gtcaatcaac gctgatgata ccgctcagcg
    25681 cattatgaca attcctggtg ttggtccgat tactgccagc ttactatcgt cgcaacttgg
    25741 tgacgggaaa cagttctcat gcagcaggga ttttgcagct tccacaggac ttgttccccg
    25801 gcagtatagc actggaggaa aatcgactct gttgggtatc agtaagcgag gtgataaaaa
    25861 tttacgccgg ttactggttc agtgtgcccg ctcattcata atgcgacttg aacgcaagca
    25921 tggaaaactt gctgagtggg ttcgggagca actcaacaag aagcattcga atgtggttac
    25981 ctgcgctctg gcaaataaac tggctcgaat tgcctgggca atcactactc agaaaaaaga
    26041 atatcaggcc tgatatagat gctgatataa ctcaattagt ttattttaaa caataagata
    26101 caagttacct ttctggtttt gcgaagactg attattgatg acatgaacgg caaatcgacc
    26161 tgattaaaaa cctaacagat gaaatggctc actgaagccg aggggatttt taggattatc
    26221 aggtgcggaa ctcatcgggg cgcgggcatc cttgcccaca gagacgccgg atagatttaa
    26281 gcaagccaac cattaatcaa aaatcagtgt tgcaaaaacg ggggtgacca tagatttcat
    26341 ctgaacagcg ggcaacaggc cgatcgactt gccgatctgg aaagaatgct acacctgttc
    26401 agcggcaaac cgatccccga caaccgggaa aacatcacca ttcatctgga tgatcacatc
    26461 cagtctgttc agggtaaaga ggactatgaa gatgagatgt tcagtatcag atactttaag
    26521 aagggctccg cgcatatcac gttcagaaaa ccagaactgg ttgatcggct aaatgacatc
    26581 attgcgaagt attatcc
//
LOCUS       DAFGPF010000065        26444 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFGPF010000065 DAFGPF010000000
VERSION     DAFGPF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26444
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.065"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1..729
                     /locus_tag="LSX49_003026"
                     /pseudo
     CDS             1..729
                     /locus_tag="LSX49_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
     gene            900..1007
                     /locus_tag="LSX49_003027"
     CDS             900..1007
                     /locus_tag="LSX49_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169408.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(1060..1818)
                     /locus_tag="LSX49_003028"
     CDS             complement(1060..1818)
                     /locus_tag="LSX49_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HBL7169409.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGQTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
     gene            2104..3033
                     /gene="pfkB"
                     /locus_tag="LSX49_003029"
     CDS             2104..3033
                     /gene="pfkB"
                     /locus_tag="LSX49_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416237.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HBL7169410.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGTATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQG
                     IRCIVDSSGEALSAALAIGNIELVKPNHKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
     gene            3134..3424
                     /gene="ghoS"
                     /locus_tag="LSX49_003030"
     CDS             3134..3424
                     /gene="ghoS"
                     /locus_tag="LSX49_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HBL7169411.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDDG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTHSATGKDPEITITTWEEWNSNRK"
     gene            3530..4390
                     /locus_tag="LSX49_003031"
     CDS             3530..4390
                     /locus_tag="LSX49_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBL7169412.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGRDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(4431..4967)
                     /locus_tag="LSX49_003032"
     CDS             complement(4431..4967)
                     /locus_tag="LSX49_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HBL7169413.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENQE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            5114..5782
                     /gene="hxpB"
                     /locus_tag="LSX49_003033"
     CDS             5114..5782
                     /gene="hxpB"
                     /locus_tag="LSX49_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HBL7169414.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVEQVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLANVKLSSLTELTAK
                     DLLG"
     gene            5946..6536
                     /locus_tag="LSX49_003034"
     CDS             5946..6536
                     /locus_tag="LSX49_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310461.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL7169415.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPESWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            6669..8060
                     /gene="tcyP"
                     /locus_tag="LSX49_003035"
     CDS             6669..8060
                     /gene="tcyP"
                     /locus_tag="LSX49_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HBL7169416.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLTA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGLLLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHR"
     gene            complement(8107..8370)
                     /gene="cedA"
                     /locus_tag="LSX49_003036"
     CDS             complement(8107..8370)
                     /gene="cedA"
                     /locus_tag="LSX49_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HBL7169417.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQENEVEE"
     gene            8553..10814
                     /gene="katE"
                     /locus_tag="LSX49_003037"
     CDS             8553..10814
                     /gene="katE"
                     /locus_tag="LSX49_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HBL7169418.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDTNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAVPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQVAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     RLFWLSQTPFEHRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPNVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIANNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIAEADRADGSFMDELLTLMTAHR
                     VWSRIPKIDKIPA"
     gene            complement(10861..11619)
                     /gene="chbG"
                     /locus_tag="LSX49_003038"
     CDS             complement(10861..11619)
                     /gene="chbG"
                     /locus_tag="LSX49_003038"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBL7169419.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVAKFAAEEGIALRIDRQSLSKDG
                     DLPANLRSSQGFSSAFYGEEISETLFLQVLDDSSHRGERSLEVMCHPAFIDNTIRQSA
                     YCFPRLTELDVLTSASLKYAIAERGYRLGSYHDV"
     gene            complement(11632..12984)
                     /gene="celF"
                     /locus_tag="LSX49_003039"
                     /gene_synonym="chbF"
     CDS             complement(11632..12984)
                     /gene="celF"
                     /locus_tag="LSX49_003039"
                     /gene_synonym="chbF"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL7169420.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGG
                     KAKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASGVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGHIDNIPADWAVEMTCTLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(13087..13929)
                     /gene="chbR"
                     /locus_tag="LSX49_003040"
     CDS             complement(13087..13929)
                     /gene="chbR"
                     /locus_tag="LSX49_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HBL7169421.1"
                     /translation="MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDY
                     YEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
                     YREEQVIDDIPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLT
                     EFNQ"
     gene            complement(13937..14287)
                     /gene="chbA"
                     /locus_tag="LSX49_003041"
     CDS             complement(13937..14287)
                     /gene="chbA"
                     /locus_tag="LSX49_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HBL7169422.1"
                     /translation="MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKMKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(14338..15695)
                     /gene="chbC"
                     /locus_tag="LSX49_003042"
                     /pseudo
     CDS             complement(14338..15695)
                     /gene="chbC"
                     /locus_tag="LSX49_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
     gene            complement(15780..16100)
                     /gene="chbB"
                     /locus_tag="LSX49_003043"
     CDS             complement(15780..16100)
                     /gene="chbB"
                     /locus_tag="LSX49_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HBL7169423.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(16399..16737)
                     /gene="osmE"
                     /locus_tag="LSX49_003044"
     CDS             complement(16399..16737)
                     /gene="osmE"
                     /locus_tag="LSX49_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HBL7169424.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQATK"
     gene            16939..17766
                     /gene="nadE"
                     /locus_tag="LSX49_003045"
     CDS             16939..17766
                     /gene="nadE"
                     /locus_tag="LSX49_003045"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBL7169425.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSIDFLKSYLQTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAIRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            17996..18883
                     /gene="cho"
                     /locus_tag="LSX49_003046"
     CDS             17996..18883
                     /gene="cho"
                     /locus_tag="LSX49_003046"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HBL7169426.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRASNLFGLFANRRAALQALQTIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQALERLRVVCW
                     PWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLKEATTLIRAPAGFDHDGYKILCKPL
                     LSGNYEITELDPVNDQQAS"
     gene            complement(18843..19418)
                     /gene="ves"
                     /locus_tag="LSX49_003047"
     CDS             complement(18843..19418)
                     /gene="ves"
                     /locus_tag="LSX49_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310475.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HBL7169427.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASITSIA
                     ANGEFSLFPGMERIVTLLEGGEMFLESADRFNHTLKPLQPFSFAADLVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(19621..20106)
                     /gene="spy"
                     /locus_tag="LSX49_003048"
     CDS             complement(19621..20106)
                     /gene="spy"
                     /locus_tag="LSX49_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HBL7169428.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKF
                     GPHEDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAE
                     AQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(20436..21404)
                     /gene="astE"
                     /locus_tag="LSX49_003049"
     CDS             complement(20436..21404)
                     /gene="astE"
                     /locus_tag="LSX49_003049"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HBL7169429.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPRFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMANDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(21397..22740)
                     /gene="astB"
                     /locus_tag="LSX49_003050"
     CDS             complement(21397..22740)
                     /gene="astB"
                     /locus_tag="LSX49_003050"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HBL7169430.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQ
                     GLLKMKKLADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEKKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLAN
                     LRARVSGFMAIEVPTAQVSVSDAVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWCY
                     LNELLAADNPISSLKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLREGREALDTLTQLLDLGSVYPFQREGGGNG"
     gene            complement(22737..24215)
                     /gene="astD"
                     /locus_tag="LSX49_003051"
     CDS             complement(22737..24215)
                     /gene="astD"
                     /locus_tag="LSX49_003051"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HBL7169431.1"
                     /translation="MTLWINGDWVTGQGALRVKRNPVSGEVLWQGNDADAAQVEQACR
                     AARAAFPRWARLSFSDRQVRVERFAGLLESNKAELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLLPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGTQGDAFLARLVAVSQRLTPGTWDDEPQPFIGGLISEQAAQQVVTAW
                     QELEAMGGRPLLAPRLLQAGTSLLTPGIIEMTGVTGVPDEEVFGPLLRVWRYDNFDEA
                     IRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(24212..25246)
                     /gene="astA"
                     /locus_tag="LSX49_003052"
     CDS             complement(24212..25246)
                     /gene="astA"
                     /locus_tag="LSX49_003052"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HBL7169432.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSVRIERAI
                     KTWQGELPKSEQGYVFVLEDSESGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(25243..>26444)
                     /gene="astC"
                     /locus_tag="LSX49_003053"
     CDS             complement(25243..>26444)
                     /gene="astC"
                     /locus_tag="LSX49_003053"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HBL7169433.1"
                     /translation="ENFDEWMIPVYAPAPFIPVRGEGSRLWEQQGKEYIDFAGGIAVN
                     ALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEAN
                     EAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPPDIRH
                     AAYNDINSASALIDDATCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEV
                     QTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYG
                     GNPLASAVAGKVLDLINTPEMLNGVKQRHDWFVERLNSINHHYSLFSEVRGLGLLIGC
                     VLNADYAGQAKQLSQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLERFAAACEH
                     FVSRGSS"
BASE COUNT         6725 a         6898 c         6267 g         6554 t
ORIGIN      
        1 tcatttcctt atttctggaa accacgccta ttaaagctaa ccatttgcga agcatactgg
       61 attatattga acgggaacag ttaactgccg aaaaacgtaa ccattgcatg aaactgtcca
      121 aaaaaattca tagagaaaaa accatacagc caacagtaaa tctcaatgat agtgtatttt
      181 ttcgcaatct ccttctgaca ctattttttg tcgccatccg tcattacaat acgcccttga
      241 ttcattgaga aatggaaaag gcaaagtcaa cctgattaaa cattactcct ccattgaatc
      301 catacagcag catgttccct tagtccggga cgcggaattc agagcattac ttcgccatcc
      361 tcttgcaagg agtcgcgtta tcgcgagtca ggattttggc tttgctttag atattttctt
      421 ctgtcgaatg atggcaaaca atgtcagtca tatgtccgcg attttatata tagacaatca
      481 tactttgtca gtaagtaaag atgtcgtgtt atcttatata tcaacgttgg gtacttttga
      541 aaaaaatatt cttttagcca acgtcagtta tttacactgt tggccgctaa aaatcatgac
      601 aacatgtcag ctgttcatat agccattcat cataatcatc ataaaactgt agaaacatat
      661 tatgctgcta taaatgtaat cagccaaagc ctgagtttta gtgctgatga actaaagacg
      721 tatttataac ccgctattta tgatatttgt atatcgatac ataatttttt tcataaaatg
      781 cagaaacagt gaccaggtgt acaacgccac ccgacgactg taataacaaa aaatcccttg
      841 atgcctgtcc cttttgttac actccgttat cacgcacaag agatatgcag gacactggta
      901 tgccgactaa acgctttgat aaaaaacact ggaagatggt ggtggtgcta ctggcaatct
      961 gtggcgctat gttgttgcta cgttgggcag caatgatttg gggctgagca gtgacaaacg
     1021 aaaacagcca gaccgcataa cacggtccgg cagataattt tacatgctgt aacccaacga
     1081 taaggttgtc cgacgatcgg tatgttccgg tgcagactct ggaggttcag agttccatgt
     1141 aacgttgtaa gccaccttca gtccaaaatg ttcattaata gcaacattta atgcgctttc
     1201 ggagttcagc gttgtgtctt ccgcgccaaa gaccgaaaca ccctgcgtaa atttagcgtt
     1261 gtcagtcaac tgccatgcat aagccccgga ggcatagccc agcggctggg tttcactggc
     1321 attgtcggta tatttgtcgt aacgcacacc agggccgaat tcaaagcgga aactgtgtac
     1381 cgggccattc aaaaactggc gaccataacc cgcggtcaac acatcgcgct ctcgatagcc
     1441 gttataacgg tctgtcagcc agcttgcctg accaaataaa tagtcataat cagttaaatt
     1501 aaaacggcta cgcccgcccg ccgcatattt ttctgaagaa cgctcatcat tagaagaagt
     1561 attactggcg ttcccccaca gcgaccaggc agtggtttgt ccataccagg tcatagtggt
     1621 gtcagccgta agtgaggagc ttttcgtatt gcctgattgt gcaagatatc ctgcgttcag
     1681 attaccttcg aaaggttttt tagcgctggc aggatcgtcc atgacagtaa aaacggaatc
     1741 atcggcagct gcattcagtg acgcaaacat gccccccgcc aacataacga tggcaggaac
     1801 tgtcttcaaa agcttcattt atcaagagtc cgtacaacaa aaaaagagac catcgcggtc
     1861 ccggaaactt tcttaaggat aaagattagc gtccctggaa aggtaacgaa ttataaaaag
     1921 gcgcgaataa cttagcaatg tattcttatt tcattttttg aataagcatg tggcgaaaac
     1981 agatttttat ttatatatat ttatctgcaa atttttaagt aaagctccaa taaatcatat
     2041 tgttaatttc ttcactttcc gctgattcgg tgccagactg aaatcagcct ataggaggaa
     2101 atgatggtac gtatctatac gttgacactt gcgccctcac tcgatagcgc aacaattacc
     2161 ccgcaaattt atcccgaagg aaaactgcgc tgtaccgcac cggtattcga acccggaggc
     2221 ggcggcatca acgtcgcccg cgccattgcc catctgggag gcactgccac agcgatcttc
     2281 ccggcgggtg gcgcgaccgg cgaacatctg gtttcactgt tggcggatga aaatgtcccc
     2341 gtcgctactg tagaagccaa agactggacc cggcagaatt tacacgtaca tgtggaagca
     2401 agcggtgagc agtatcgttt tgttatgcca ggcgcggcat taaatgaaga tgagtttcgc
     2461 cagctcgaag agcaagttct ggaaattgaa tccggggcca tcctggtcat aagcggaagc
     2521 ctgccgccag gtgtgaagct ggaaaaatta acccaactga tttccgctgc gcaaaaacaa
     2581 gggatccgct gcatcgtcga cagttctggc gaagcgttaa gtgcagcact ggcgattggt
     2641 aacatcgagt tggttaagcc taaccacaaa gaactcagtg cgctggtaaa tcgcgaactc
     2701 acccagccag acgatgtccg caaagccgcg caggaaatcg ttaatagcgg caaggccaaa
     2761 cgggttgtcg tttccctggg tccacaaggg gcgctgggcg ttgatagtga aaactgcatt
     2821 caggtggtgc caccaccggt gaaaagccag agtaccgttg gcgctggtga cagcatggtc
     2881 ggcgcgatga cacttaaact ggcagaaaat gcttctcttg aagagatggt ccgttttggc
     2941 gtagctgcgg ggagtgcagc cacactcaac cagggaacac gcctgtgctc ccatgacgat
     3001 acgcaaaaaa tttacgctta cctttcccgc taacaaaaac attcccccag cattggggga
     3061 atcaccacca acctgtcggc aacgcgtttc tccgactatg ctcaaaagtc atgtgataac
     3121 aaaggggtga actatggcca gtggcgatct tgtccgttat gtaataaccg tcatgttgca
     3181 tgaggataca ttgactgaaa ttaacgagtt gaataattac ctgactcgcg acggtttttt
     3241 gctcaccatg acagatgatg atggcaatat ccatgagctg gggactaaca cttttggact
     3301 tatcagtacc caaagtgaag aagaaattag agaactggtt tcggggctta cccacagtgc
     3361 aaccggcaaa gatcctgaaa tcaccatcac gacctgggag gaatggaata gcaacagaaa
     3421 ataaatggtt tttgggcaat aatcagtctg tggtgtgcgt tagctcgtgt ttttacaccg
     3481 cattcttgcg ctaaccttat gatctggcag acaacatggg agagacatca tgtggcaggc
     3541 aatcagtcgt cttttgagcg agcagttagg tgaaggcgaa atagaactgc gtaatgaact
     3601 gcctggcgga gaagtccatg ccgcatggca tttgcgctat gcaggacgtg actttttcgt
     3661 caaatgtgat gaaagggaac tgcttcccgg ttttaccgcc gaagccgacc aactggagtt
     3721 actgtcgcgt agtaaaaccg tcaccgtgcc taaggtttgg gcagttggcg ctgaccgtga
     3781 ctacagtttt ctggtgatgg attatctccc acctcgcccg ctggatgcgc atagtgcatt
     3841 tattcttggt cagcaaattg cgcgtttaca tcaatggagc gaccaaccac aatttggcct
     3901 cgatttcgat aacgcgctct ccacaactcc acagcccaac acctggcaac gtcgctggtc
     3961 aacttttttt gctgaacaac ggattggctg gcagctggaa ctggcggcag aaaaagggat
     4021 cgctttcggc aatatcgatg ccatcgtcga gcatattcag cagcgtcttg cctcgcatca
     4081 accgcagcct tctctgttgc acggcgattt atggtccggc aactgtgcgc tgggtccgga
     4141 tggcccgtac attttcgacc cggcctgtta ctggggtgac cgagagtgcg acctggcgat
     4201 gttaccgctg catactgaac agccgccaca aatctatgac ggctatcagt cagtatcccc
     4261 gctacctgcc gatttccttg aacgtcaacc ggtttaccaa ctctacacgc tgttaaatcg
     4321 tgcaaggtta tttggcggtc agcatttggt tattgctcag cagtcactgg atagattatt
     4381 agcagcatga tatgggttga ggataatggc cgctccgtgc ggccttttga ttaaataaac
     4441 ccaagcagag aaaagaacac ataacctgca gcaatacaaa taaccggcag gatatacagc
     4501 gagaaaaact gcaggaaaat agtatggtgc ggaacaacaa tacgtgactc aatttgttca
     4561 cgcgttagcc cctcttcccc tttggctttt tccagaatga gttgatcttc aacaccttcc
     4621 cgcaagaagc gcgcctggcg actcatccgg gctccggaat cctgcaacgc cagtccgaca
     4681 aaaatcagga tgaaaatcac ccagaacata acgttcacgc caccattaaa attgggcgtc
     4741 ggagagttgt accagaacag attcaaaaaa ggcgtattcg cctgcatcat atcgatcatg
     4801 acatgagtaa agtcgagcat gaccgcatta atgccttcct ggttttcctg ccgggtattc
     4861 ataaatttca gcaaagaaat caatgtagag atcaatgcag gtataaaaat cacccaaccc
     4921 aaaatccttt tcaaaacagc aatgcgtcca gcttgttgat acgtcatgag ttctccttga
     4981 ttaagacgcg tcgtttcact tagtttacct gtagatatct gttttcgccc attctttaaa
     5041 ggcgatatga taggcgctta atcataagca cggcttaata ccttacatat aatgctctaa
     5101 aggagaggtt gtaatgtcaa ccccgcgtca gattcttgct gcaatttttg atatggatgg
     5161 attacttatc gactcagaac ctttatggga tcgagccgaa ctggatgtga tggcaagcct
     5221 gggggtggat atctcccgtc gtaacgagct gccggacacc ttaggtttac gcatcgatat
     5281 ggtggtcgat ctttggtacg cccggcaacc atggaatggg ccaagccgtc aggaagtagt
     5341 agaacaagtt attgcccgtg ccatttcact ggttgaagag acacgtccat tattgccagg
     5401 tgtgcgtgaa gccgttgcgt tatgcaaaga acaaggttta ttggtggggc tggcctccgc
     5461 gtcaccgctg catatgctgg aaaaagtatt gaccatgttt gatttacgcg acagtttcga
     5521 tgccctcgcc tcggctgaaa aactgcctta cagcaagccg catccgcaag tatatcttga
     5581 ctgcgcagca aaactggggg ttgaccctct gacctgcgtg gcactggaag attcggtaaa
     5641 tggcatgatc gcctctaaag cagcccgcat gcgttccatc gtcgttcctg cgccagaagc
     5701 gcaaaatgat ccacgttttg tattagcaaa cgtcaaactc tcatcgctga cagaactcac
     5761 cgcaaaagac cttctcggtt aatgaccagg gggcagtgat cacactgccc ctggttcttt
     5821 atctgaattt gcattcaaat gacggattaa tcgccaattt aagagaaaga gttacaccgt
     5881 caccacttcc gtgcactgta taaaaaccct atactgtacg tatcgacagt ttagtgagtt
     5941 ttatcatgac ggcggaaggt caccttctct tttctattgc ttgtgcggta tttgccaaaa
     6001 atgccgagct gacgcccgtg ctggcacagg gggactggtg gcatattgtc ccttccgcaa
     6061 tcctgacgtg tttgttaccg gacatcgatc acccaaagtc gtttcttggg cagcgattaa
     6121 agtggatatc aaaaccgatc gcccgcgctt ttgggcatcg tggttttacc cacagcctgc
     6181 tggcggtatt tgcgctgctg gcaacctttt accttaaggt tcctgaaagc tggttcattc
     6241 cggctgatgc gttgcagggt atggtgctgg gttatttgag ccacatactt gccgatatgc
     6301 tgacacccgc cggtgttccc ctgctctggc catgccgctg gcgtttccgc ttgcctatcc
     6361 tggttcccca aaagggcaac caactggaac gttttatctg catggcatta tttgtctggt
     6421 cggtatggat gccccattca ttacccgaaa acagcgctgt tcgttggtca tcgcaaatga
     6481 tcaatacctt acagatccag tttcatcggc ttattaagca tcaggttgaa tactaaaaag
     6541 gcaaaaatcg cctttctgga ataagcaatt ccatttgaat ataagagcca gctcacagtt
     6601 ctgttaatct tgcgccaaca ctatgactgc tacgcagtga tagaaataat aagatcagga
     6661 gaacggggat gaactttcca ttaattgcga acatcgtggt gttcgttgta ctgctgtttg
     6721 cgctggctca aacccgccac aaacagtgga gtctggcgaa aaaagtgctg gtgggtcttg
     6781 tgatgggtgt ggtttttggc cttgccctgc ataccattta tggttctgac agccaggtac
     6841 ttaaagattc tgtacagtgg tttaacattg ttggtaacgg ctatgttcaa ctgctgcaaa
     6901 tgatcgttat gccgctagtc ttcgcctcta ttctgagcgc ggttgcccgt ctgcataacg
     6961 catctcagtt aggcaaaatc agttttctga ccatcggtac gcttttgttt accacgctga
     7021 ttgcagcgct ggttggtgtg ctggtcacca acctgtttgg tttgacggct gaaggtctgg
     7081 ttcagggtgg tgcagaaact gcacgtctga acgccatcga aagtaactat gttggtaaag
     7141 tctctgacct gagcgttccg cagctggtct tgtcctttat cccgaaaaac ccgtttgccg
     7201 atctgaccgg agccaatccg acgtcaatta tcagcgtggt aatttttgcc gcattcctcg
     7261 gcgtagctgc gctgaaactg ctgaaggatg atgcgccgaa aggtgaacgc gtcttaaccg
     7321 ctatcgatac cctgcaaagc tgggtgatga aactggttcg cctggtcatg cagttgaccc
     7381 cttacggtgt tctggcgctg atgaccaaag tggttgcagg ttctaacctg caagacatca
     7441 tcaaactggg aagtttcgtt gtcgcgtcct acctcggtct gctgattatg tttgcagtgc
     7501 atggccttct gctgggcatt aatggcgtga gcccgctgaa gtacttccgt aaggtatggc
     7561 cagtactgac gtttgccttt accagccgtt ccagtgctgc gtctatccca ctgaatgtgg
     7621 aagcacaaac gcgtcgtctg ggtgttcctg aatccatcgc cagtttcgcc gcctctttcg
     7681 gtgcgaccat tggtcagaac ggttgtgccg gtttgtatcc ggcaatgctg gcggtgatgg
     7741 ttgcgcctac ggtgggcatt aacccgctgg acccgatgtg gattgcgacg ctggtcggta
     7801 ttgtcaccgt tagttccgca ggcgttgccg gtgtcggtgg tggtgcaact ttcgccgcac
     7861 tgattgtgct gcctgcgatg ggcctgccgg taacactggt ggcattgtta atctccgttg
     7921 aaccgcttat cgacatgggc cgtacggcgc taaacgttag tggctcgatg accgctggca
     7981 cgctgaccag ccagtggctg aagcaaaccg ataaagccat tctggatagc gaagacgacg
     8041 ccgaactggc acaccgttaa tcctgatttg ttacgttaaa cgcctgtcat cccgacaggt
     8101 gtttttttat tcttcgacct cattttcctg gcggatctga tttgcccaac gctgggcgga
     8161 ttcaggcaca gtaaacgccg gtgagcgcag aaatgactcc cccatcagta caaacgcaac
     8221 atatttgcca cgcagcatcc agacatctcg aaacgaatcc atctttatcg catgttctgg
     8281 cggcgcgggt tccgtgcgtg ggacatagct aataatctgg cggttttgct gacggagcgg
     8341 tttcttcatt actggcttca ctaaacgcat attaaaaatc agaaaaactg tagtttagcc
     8401 gatttagccc ctgtacgtcc cgctttgcgt gtatttcata acaccgtttc cagaatagtt
     8461 tccgaagcgg gatctggctg gtggtctata gttagagggt tttttgacca aaacagcggc
     8521 cctttcagta ataatttaag gagacgagtt caatgtcgca acataacgaa aagaacccac
     8581 atcagcacca gtcaccacta cacgattcca gcgaagcgaa accggggatg gactcactgg
     8641 cacctgaaga cggatctcat cgtccagcgg ctgaaccaac accgcctggt gcacaaccta
     8701 ccgccccagg gagcctgaaa gcccctgata cgcgtaacga aaaacttaat tctctggaag
     8761 acgtacgcaa aggcagtgaa aattatgcgc tgaccactaa tcagggcgtg cgcatcgccg
     8821 acgatcaaaa ctcactgcgt gccggtagcc gtggtccaac tctgctggaa gattttattc
     8881 tgcgcgagaa aatcactcac tttgaccatg agcgcatccc ggaacgtatt gttcatgcac
     8941 gcggatcagc agctcacggt tatttccagc catataaaag cttaagcgat atcaccaaag
     9001 cggatttcct ctcagatacg aacaaaatca ccccagtatt tgttaggttc tctaccgttc
     9061 agggcggcgc tggctctgcc gataccgtgc gtgatatccg tggctttgcc accaagttct
     9121 atactgaaga gggtattttt gacctcgttg gcaataacac gccaatcttc tttatccagg
     9181 atgcgcataa attccccgat tttgttcatg cggtaaaacc agaaccgcac tgggcagttc
     9241 cacaagggca aagtgcccac gatactttct gggattatgt ttctctgcaa cctgaaactc
     9301 tgcacaacgt gatgtgggca atgtcggatc gcggtatccc gcgcagttac cgcactatgg
     9361 aaggcttcgg tattcatacc ttccgcctga ttaatgccga agggaaggca acgttcgtac
     9421 gtttccactg gaaaccactg gcaggtaaag cctcactcgt ttgggatgaa gcacaaaaac
     9481 taaccggacg tgacccggac ttccaccgcc gcgagttgtg ggaagcgatt gaagcaggcg
     9541 attttcctga atacgaactg ggcttccagt tgattcctga agaagacgaa ttcaagttcg
     9601 acttcgatct tctcgatcca accaaactta tcccggaaga attggtgccc gttcagcgtg
     9661 tcggcaaaat ggtgctcaat cgtaatccgg ataacttctt tgctgaaaac gaacaggtgg
     9721 ctttccatcc agggcatatt gtccccggtc tggatttcac caacgacccg ttattgcagg
     9781 ggcgtttgtt ctcttatacc gatacacaaa tcagtcgtct tggtgggccg aatttccatg
     9841 aaattccgat taaccgcccg acctgccctt accataattt ccagcgtgac ggcatgcatc
     9901 gtatggggat cgacactaac ccggcgaatt acgaaccgaa ctcgatcaac gataactggc
     9961 cgcgcgaaac accgccgggg ccaaaacgtg gcggttttga atcataccag gaacgcgtgg
    10021 aaggcaataa agttcgcgag cgcagtccat cgtttggcga atattattcc catccgcgtc
    10081 tgttctggct aagtcagacg ccattcgagc atcgccatat tgtcgatggt ttcagttttg
    10141 agttaagcaa agtagttcgg ccgtatattc gtgagcgcgt tgttgaccag ctggcgcata
    10201 ttgatctcac tctggcccag gcggtggcga aaaatctcgg tatcgaactg actgacgacc
    10261 agttgaatat caccccgcct ccgaacgtca acggtctgaa aaaggatcca tccttaagtc
    10321 tgtacgccat tcctgacggt gatgtgaaag gtcgcgtggt agcaattttg cttaatgatg
    10381 aagtgagatc ggcagacctt ctggccattc tcaaggcgct gaaggccaaa ggcgttcatg
    10441 ccaaactgct ctactcgcga atgggggaag tgactgcgga tgacggtacg gtgttgccta
    10501 tagctgctac ctttgccggt gcgccttcgc tgacggtcga tgcagtcatt gtcccttgcg
    10561 gcaatattgc ggatatcgct aacaacggcg atgccaacta ctatctgatg gaagcctaca
    10621 aacaccttaa accgattgcg ctggcaggag acgcgcgcaa gtttaaagca acaatcaagg
    10681 tcgctgacca gggtgaagaa gggattgcgg aagctgaccg cgccgatggt agttttatgg
    10741 atgaactgtt aacgctgatg acagcacacc gcgtgtggtc acgcattcct aagattgaca
    10801 aaatcccggc gtaaatatgg ataaggtcac gccccctggg gagtgacctt accaccttac
    10861 ttacacatca tgataactac ccaaccgata accacgctca gcaatcgcat atttcaacga
    10921 cgctgaagtc agcacatcca gttccgttaa ccgagggaag caataagcac tctggcgaat
    10981 cgtattatcg ataaacgccg ggtggcacat cacttccagc gagcgctcgc cgcgatgact
    11041 ggagtcatca agcacttgca ggaacagtgt ctcgctaatc tcttcaccat aaaacgcgct
    11101 actgaatccc tgcgaactgc gcagattagc cggtaaatca ccatccttag aaagcgactg
    11161 acggtcgatg cgcaacgcaa tcccctcttc agccgcaaac tttgccacaa tcgggaaaat
    11221 ctgcgggaac atatgcacat gatgatggct atcaagatgc gtaggtttgc gtccaaatag
    11281 ctcaatgaaa cgcaaatact gactggcgag ctcctgagta atttcttcca gcggtaaagc
    11341 atcttcttct gccaactgcc agatccattt tcccagcaca ccatcgcggg ttaaccccgg
    11401 catagctgtc agaggcttgc ccatagtaag gacaaagtgc atccctatgg ccagactcgg
    11461 ttcatcacgg ctcaactgca ccgcatggtc aatagcctgc ccattcacca gcgccgtcgt
    11521 cgacgtgaca atcccattgc gacaggcctc gataatgccg tagttctgac ctttgcttaa
    11581 gccaaaatca tcagcattaa caatcagtaa gcgttccata atcagcctcg gttaatgtgc
    11641 ttttttaagc tctgcgatgc agtcggcaaa atttggcagc catttctcgt gcgccagaat
    11701 catctcgcgt gccagcagct cagcatcgcg atcggaatgc accaacggac taaggtttag
    11761 cgccagtaag acatcgttaa attctccact aagtgcggcg ttgctggcag caatctcgaa
    11821 gcctttgatg gtgtgaatca gccccatcac tttatcatcg aaatgcgtaa tgcgcggatg
    11881 tggcgtcgcg ccatcgcgcc ccagcgtaca ggtcatttct accgcccagt ctgccggaat
    11941 attatcaata tgcccatgat gcgggatatt aacgtaatgt tctgcttgct tgtcgttata
    12001 gatagcgttg atcacttcgc acgcagcatc agaataataa gccccaccgc gctgttccag
    12061 ttctttcggc ttaactttca actccgggtt tttatatagc tcaaaaagtt gtttctcgac
    12121 tttctgtacg acctgcgctc gtgcgccgcc tttgtagtat tcgcccattt caatagccag
    12181 catctctttt tgcttgaagt aataaagcaa ataagaacac ggcaacagat tcagagaacg
    12241 aattaagcct tcgctaaatg gcagatcgaa aatattttta acgccagatg cttttaactg
    12301 cccggatgcc acaccatcaa gcaattcggc aaagcgtgat ttgccattta ccagcacatc
    12361 cttaatgaac accatatggt tgaggccgaa cagatcgata gataaatcat cgctgtcttt
    12421 cagcatcaga acatcgcgaa taaacatctt catgccgatc ggaatattac acacgccgat
    12481 aaagcgttta aatccggtat gacgataaac ggcttcagtg accattcccg ccgggttagt
    12541 gaagttaatc acccatgcat tcggacatag ttcttcgaca tcttttacga tgtcaaaaat
    12601 caccggaatg gtacgcagac ctttaaacag accgcccgcg ccgttagttt cctgaccaag
    12661 ataaccatga cttaatggaa tacgttcatc cagttcccgc gccggtaatt ggccaacgcg
    12721 cagttgggta gtaacgaaat cagcatcttt caatgcttcg cggcgatcca gcgttttata
    12781 aagcttcatc gggacgccag cgttatcaat catccgttgg cagagatcaa aaataatatc
    12841 cagtttcgct ttaccacctt cgacatccac cagccataat tcgctgaccg gcaattcgtg
    12901 ataacgctta ataaatcctt ccagtaactc cggggtatag ctgctcccgc caccaatagt
    12961 gacgactttt aatttctggc tcataatttc tcccttcagt acagaatact gatatctggc
    13021 atatctgccc ccggacataa ataatccagc aacaggacag atatgtgaat tgtcaggtat
    13081 aacgacttac tgattaaatt cagtcaattt cttacgatag ctcttaggcg taaaggacgt
    13141 taatttctta aacgttttaa taaacaagct cgggctacta taaccggcct caaacgcaat
    13201 atccgtcact gaatagttgg tcatttccag ttgttttttg gcaaaattaa tacggatttc
    13261 attaataatc tgcattggcg ttttaccata atatcgttga gtcgctcgcg tcaaatattc
    13321 ctgtgatttg gctgacaacg tcaccatatt ctccagcgcc gattcactaa actgctcttt
    13381 atcatgcatt ttttctaccg tacttttcag ccactgcggt atatcatcaa tcacctgttc
    13441 ttcgcggtaa tgacgtaaac ggttaatgac ataaaaagta accatctcaa caaactcttc
    13501 cagccctgtt tcgcggaaat tcaatgaaga aatcactgtt tccacatagg tgagaaaagc
    13561 gttattggtc cggtatacct gcgaagctac aaagcaataa ggcaacaacg gcaggtaatg
    13621 ctgctcaaaa aagcgtttac tgatcccaac gttcaatata cgcgtggcac caaactcata
    13681 aaaactttga tggtgcgaac ctaacggaat aaaaacaaaa tcgccccgtt ccagtaacac
    13741 gcgcttaccg ttaatctcct ggaaataacg cccggttaat accagagtaa attcataata
    13801 gtcgtgctga tgcagtccgc tgatactctc agttttatta tagataaaca catggaagtt
    13861 tttgccatta aacaactgct gttctcgggc agtggcaatt tccggcgcgt taatcactgg
    13921 ctgcatcatc gactccttat gccttcagtt tttcatgaag ctcaattaat tcagtaatca
    13981 gttcacgcgc aagcatggac gtcattaaat gatcctgagc gtggaccagc accagactca
    14041 ctttcatctt accttcgcca gcatcgcctt caatcagttt cgtctgtacc agatgcgctt
    14101 cattcaatgc catccgtgac tgatccatca tcgcttttgc tgcggcaaaa tcgccctgct
    14161 tcgcctgttt cagtgccgca tacgccaggc tacgcgcttg tccggagttg atgataagcc
    14221 ccatcaccac ttcttccagc tcttcagctt ccgtttgcgt atcgggaata ttatcgagat
    14281 ccatcataca tcgttcctct ctattcttac cggcacgatt acccgtaccg gcatcgatta
    14341 aaatttcagg gcgttagcga tatcttcttc gctctcttct ttatcaatcg cgttttgtgc
    14401 tttgttagcg accacaacaa agggcagata aattaacgtt gcgataccaa ggttgaagag
    14461 tgcgaccagc aatgcggcga cgctaccgtt ggtgttaaag aaggctccca gaccggttgg
    14521 catggtccac ggtgcaatat tggtcaccgg tggaataatg cccatgtagt acgctgccag
    14581 ggtgattgcc gccagaatcg gttgtaccag tacaaacggg ataaacatca ccgggttcat
    14641 gataattggc agaccaaaca gaatcggttc gttaatctgg aagatgccag acggcagcgc
    14701 cagttttgcc acctgacgat aatcagcacg tcgagaggcg ataaagatag ccaggatcag
    14761 gcctaaagtc gcaccactgc caccaaggaa aataaaggag tccagcatcg gcttggccca
    14821 gatatggaag gtcttaccgg ctgccagcgc cgcttcgacg gaaccatatt gctgataggt
    14881 cgcgatattt tccagcgccc aaggcgtcat aatgccgttg tccagtgcgg tcagcgccag
    14941 cgcgccatga ataccgaaga accagagcag tggaacaaag atcacatagg cccagcctac
    15001 cacgctaccc aacgatgcca gtggggttga gatcgtatcc ataatgatct gatggaagtt
    15061 ggtgccccag gtattcaacg cccaggcaat aatccccatc acggaaagaa taataaaacc
    15121 aggaattaat gctgagaaag agcgcgaaac cgatgtcgga acgctatcag gtaacttaat
    15181 gacccagtta cgatgaacaa taaaggtaaa catttctgcc accaccaggc caataataat
    15241 cccggagatg atattcgccc cacctaacca gtttgcgcca accgcatagg cctcaccgac
    15301 actatatggg gtgacggtca taaatgctgc aacggataac aacccggccg ccagcgcatc
    15361 gactttacgc tcttctgcca gcgccatgcc aataaagaac ggtgccatta aagacattat
    15421 ccctaatgtt ccgttatata cgttgccgcc aatacctttc agaccattaa gtgtttcaat
    15481 ggttgaggca tccaggcgaa tacctaagga ataaaaaaac gacccctccc caaagcttag
    15541 aaaaacgttg ttaattaata caaacatggc cccgcaaggg ttaacggcat taagcgaata
    15601 aagccatttt tgattgcatt aacgtgtggc tgctttccta ttttaactgc aaaagggagg
    15661 agtacctttt caagcgatgc aataacatta ctcatagaaa aataccctta aaaaccgcaa
    15721 tttaaatatt gcggtattga tttatgaaat aactctttga cgggaaaatt taaaataaat
    15781 taatttgctg cggctttttt aatcgctgca accgcagcct taagcacgcc taaaccatcg
    15841 actttgccat aaagcagcga gtcaattact tcaaccggtt tgttgggtaa caaacgctgg
    15901 atttcgggca acatataagc aatctgcggc cctaataaca cgacatcggc attctgacct
    15961 ttttcaccag ccagtgtttc cggaaatgct tcaataatga ccggaacttc atatttttct
    16021 gcctgtgcgc gcatttttga taccagtaaa gaggtagaca tgcccgcaga acaaaacaga
    16081 taaatgtgtt tcttttccat aaaactgccc tcatcgacga ttatctgtca gccagacact
    16141 ccgcaagcct taacctgctt ccatgctctg ggtaacttgc gaaaccaaca tgactttttt
    16201 tgtggctgaa aggagtatac ggtataggcc tgagcaatag tatttctttg acctgataaa
    16261 ttgtctctcc ttgacctgtg gttatgaccc tcttcacatt tcgggcaaat aattcgcgaa
    16321 gataattaag aacacaggcc aaaaaaaacc ggcgcaatgg ccggtttccg ttgttactca
    16381 agctttcagg cgaagtgatt acttcgtagc ctgcggatca gtgtcgtatt cagcacaggt
    16441 ctgataaccg gagttgatga catgtccggt atcatctaac gcgacaaagt aggtttctgc
    16501 tttaccatca cgttgaccca ggatgtaggt ctggcaagta ccacgagcat ggatcatgct
    16561 cacttcagac gaaggtttac ccgcaatttg tgcaacctgc gcccggctca tgcctttttt
    16621 gacgtctttc accacaggct gtacaaactg gtctttggta cgatcataag ccgtacaacc
    16681 cgccagcatg gttaataccg ccgctgcact cagaattcct gccatattct tgttcatatt
    16741 ccgtcctctt gtttatcagc gtgttagata agcctggaat acattgggcg ctttttcaag
    16801 cccgtgaacg aaacggctcc gctttcagag gattcctgta tgacgtttta accaccattc
    16861 agcccgctgt cgcttgtcgt ttcagtagca acgggttagc tttaaggaag ttttgtcttt
    16921 tctgtctgga ggggttcaat gacattgcaa caacaaataa taaaggcgct gggcgcaaaa
    16981 ccgcagatta atgctgaaga ggaaattcgt cgtagtatcg attttctgaa aagctacctg
    17041 caaacttatc cgttcattaa atcactggtg ctcgggatca gcggcggtca ggactccacg
    17101 cttgccggta agctgtgcca gatggcgatt aatgagctgc gccaggaaac cggcaacgaa
    17161 tcactgcaat ttattgccat acgcctgccc tatggtgtcc aggctgacga acaagattgc
    17221 caggatgcca ttgcctttat tcaaccggat cgcgtattaa ccgttaatat caagggcgcg
    17281 gtactcgcca gcgaacaggc gctgcgcgaa gcgggcattg aactgagcga ttttgtccgt
    17341 ggcaatgaaa aagcgcgtga gcggatgaaa gcacaatata gcattgcggg tatgaccagt
    17401 ggtgtcgtgg tgggcaccga tcatgcagca gaagctatta ccggattctt cactaaatat
    17461 ggtgacggcg gtacggacat taatccgctg tatcgtctca acaaacgtca gggtaaacag
    17521 ttactggcgg cattaggttg cccggaacac ctttataaga aagcgccaac ggccgatctt
    17581 gaagatgatc gcccttctct accagatgaa gtggcactcg gcgtgaccta tgacaatatc
    17641 gacgactatc tggaagggaa aaacgtacct gaacaggtcg ccagaacaat agagaactgg
    17701 tatctgaaaa ccgaacataa acgccgtccg ccaattaccg ttttcgatga tttctggaaa
    17761 aagtaataat ttgcacctat tggattgtgc gaaaaagagt aatttgttca cgccggatgc
    17821 ggcgtgaacg ccttactcga cctacaaaac tatgcaaatt caatacattg caggagtcga
    17881 ataggcctga caggcgtagc acgtcagacg gtgtaacctt tgtcatcaac ccgcctcttt
    17941 tttaatcgct ccccgcctgt tacactggat agataaccag cattcggagt caacagtggt
    18001 acggcgttta acttctccgc ggctcgaatt tgaagctgcg gcaatttatg aatatcccga
    18061 acatttacgt tcattcctta atgacttacc cacccgacca ggggtgtatc tgtttcatgg
    18121 cgaaagtgac accatgccgc tctatatcgg caaaagcgtt aatatccgca gtcgggtgct
    18181 ttctcattta cgcaccccgg atgaagccgc catgctgcga caatcccgac gcatcagctg
    18241 gatatgtacc gccggtgaaa tcggcgctct actccttgaa gcgcgattaa tcaaagagca
    18301 gcagccgctg tttaataaac gcttgcgccg caatcgccag ctctgcgccc tgcaattaaa
    18361 tgaaaagcgt gttgatgtgg tgtatgccaa agaggtggat ttttcacgag cctccaacct
    18421 gtttggcctg tttgccaata ggcgcgcagc tttgcaagca ttgcagacca tcgccgatga
    18481 acaaaaactt tgttatggcc tgttgggact ggaaccgtta agccgcggtc gtgcatgttt
    18541 tcgttctgca ttaaaacgtt gcgccggggc gtgttgcggt aaagagagcc atgaggaaca
    18601 tgcgctacgc ttgcgccagg ctctggagcg tttgcgggtg gtgtgttggc cttggcaagg
    18661 cgcggtggca ttgaaagaac agcacccgga aatgactcaa tatcatatta ttcaaaactg
    18721 gctgtggctg ggggcggtta attcgctgaa agaagcgaca acgttaattc gggcacccgc
    18781 cgggtttgat cacgacggtt ataaaattct ttgtaagccg ctgctttccg gtaactatga
    18841 aattactgaa cttgatccgg tgaatgacca gcaagccagt tgatttcact gaacaacagt
    18901 ttaccttgcg gttgcaaaag ccgcagggtg tgcctgccat cgaaccagca cgcgccctgg
    18961 tcggtagtga gcagtttgtc gcccaattgc cacgccccgt ttattacaaa caccaccccg
    19021 ccgcgtgaac caaaggtggt aaacgtacgt tcggcaattc tgactttcgc cttacagaca
    19081 tccaggcgtg tcatgatgtt gaaatccatc gacatctgcc ctgccgtcag tttcgctttt
    19141 accaccagat ccgctgcaaa ggaaaaaggt tgtaacggtt ttaaggtatg gttaaagcgg
    19201 tctgcgcttt caaggaacat ctcgccgcct tccagcaacg tcactatcct ttccataccg
    19261 ggaaacaaag aaaactcccc attcgccgcg atggatgtaa tgctggcacg ccagtaaaaa
    19321 tcacgttttg ccggtgggaa agtgcaaatt tcgcgcgttt caccggcagc gtttcgccac
    19381 agattcaccg acattttacg catatcaaag tattccatac ccgctcccgg cccgttcttt
    19441 tcattgttat cgttcaggta accgtggatg gttatcggca actcgggtga tttacgttag
    19501 tggcgatcag gctttttttg catctgtttg agaagagaaa agaaaaccgc cgatcctgtc
    19561 caccgcatta ctgcaaggta gtggacaaga ccggcggtct tacgtttttt ggctgaaaga
    19621 ttattcagca gttgcaggca ttttaccttt tgccgctgga cgttctgtca gacgcttctc
    19681 aaaattagca ttaaattgct ttttctgttc cggcgtcagg atgttgtaaa tcttgttctg
    19741 ggtttccatg tgcgccagca tgttagcttt gcgctgttct tccatttttg cgatctgcgc
    19801 ttcagctttt gctttatcga aggtatcgct ggcaatgatg tcatgcattg cgcggcgttc
    19861 ttccagtggc ggacgtttca tctggtcacg ctggcctttc atgatttcgc ggatctgctg
    19921 tttctgcgcg tcggtcaggt tcaggtcttt gaacatcatg tcctcatgcg gaccgaactt
    19981 gcctttatgg tgcatcatcg gcttcgcgtc agccggtgct gcagtagtgg tgtctgcggc
    20041 atgggccagg ttagccgcgc caagagccag ggtagaggca acaaacagtg cagttaattt
    20101 acgcatattc tatatccttc ctttcagtta tttattacgg ctttcttaag tagcgtgccg
    20161 tgttgacgag attaacttta ctgactttag cgtcaattaa tcagagcaac ggtaaaacaa
    20221 tgaaagtgta aaaaacactt ttgcgccaat tatggagaaa aaaagaaaat ttgatggaga
    20281 gtgatgagag aatattacaa cacgatgatt ttgcagagat tatgaagaac tataccggat
    20341 gactggtgat aaataaagca aataaccagg attaatctgt attaatttat aagaaagcaa
    20401 cttaataccc gcagaatgat ttctgcgggt aagtattagc ttattttttc gagcattaat
    20461 cccgcacgta atcccaacgc taccaacgga ttagggaata acacatactc tacatcatgg
    20521 gttacggtaa aacgttcctc cccgtcctgc gccagcaatg ttcctttctc aaacggcata
    20581 aaattcagcg tgtcatttgc catatgcatt tcgaaggacg gcgagtggcg agtaatttgc
    20641 gaaaccaccc gataacggag cggcggtgtt ctcacgatac cgacactctc accagatagc
    20701 agcgcagcaa ttgcgctggc agttactgca aactggcgaa gatcgttttg tccaaagggc
    20761 aacgctttgc cgagttccag cgtacaggcc agcgcgccaa aatgtctggc gctgaaatgg
    20821 gtaaacgtac caccaggctc ctgatggaac accagtgcct ccagacccgc cgcacccagc
    20881 cacgtcagaa atttctcgtc ccagggaatg tcgcgttgcg gtaatacacc gaaccgcgga
    20941 tgcaaggagc cacgaattgc ggtatggaga tcaaggtgcc agcgcacaga ttctttgccc
    21001 tggtcataaa aatcttccag gcactgttcc agttcgcgcg cccgacaggt ttccccgctt
    21061 tcagcaaata gctgccaacg accgccaaac attcggttca tatcgctatg gcaataacgt
    21121 ttcccttgct tcagcgcagg aggattcccg aggatcacca gcaaccgcca acgtaacggg
    21181 atctcgccgt gagatatcgc gccaagcaac gcatccagca tttccacagg tgccgtctca
    21241 ttaccgtgta ttcccgctga aatcaccagt gcgccttgcg gtggcgttaa tggcgtcagt
    21301 tccagcacgc catcgcccag ccagcgccag cgaacgccgt tgatttctcg ctcggtgata
    21361 accggttttt tacccgttaa ggtcagagca agaaaattat ccatttcccc ctccctcgcg
    21421 ctggaatgga taaaccgaac caagatccaa taattgagtc agtgtatcca gcgcttcccg
    21481 tccttcgcgc agcaattgtg gatcggcaag atccgccgca gtaagacgat cgcggtagta
    21541 acgatccacc cagtcattga gcgcattaaa cagcgtatcg ttcatcatca ccgccggatt
    21601 caccgcccgg cgttcttctt ctgtcaacac cacgcgcagc cgcaggcacg ccgggccacc
    21661 gccattcgcc atgctttcac gtaaatcaaa aacttttagt gagcttattg ggttatcggc
    21721 agcaagcaat tcattgagat aacaccatac tccagcatgt tcccgacatt cctgaggcag
    21781 caccaacatc atggaaccat catcgcggct cagcagttgg ctgttaaaca gataagtaga
    21841 caccgcatct gacacggaaa cctgcgccgt gggcacctct attgccataa aaccactgac
    21901 ccgtgcacgc agatttgcca gtaactgtga ctggcgagcg aacgcctgtt gatggcaaaa
    21961 cagcacctgg cggttactca cggcaatcac gtcattatga aaaacgccct ggtcgataac
    22021 gtccgggttt tgctgggcga aaatcacctg ttggggattc acctgattca accttgccac
    22081 cgcctcgctg gcttcacggg tctgccgcgc cggataacgg gaaggccggg tatcattgcc
    22141 ctcttctcgc ccgtagacaa aaagttgcat acccggttca ccgtaatgac cgccgagacg
    22201 attgtggttt gccgccccct catcaccgag caaggctacc tgcggcaacg ccgaatggac
    22261 gctaaatttc ttttcgtcgt taaaaatcgc ttttaacagc gattcggtga cgggggcttc
    22321 cagcgaacgg tgaaatttat tgttcaggtt agcaacagtg agatgcactt tgccatccag
    22381 cgtatcggcg gatggcgcga tcgttgccgc attggctacc cacattggcg aagcggaact
    22441 gacgctggaa agccagtgcg gtgcctggcg tgcaactttt tccagtacct gctcatcgct
    22501 accactgaat cccaactgac gcagcaccgg aataaacgga cgctcgtgcg gcgggatcac
    22561 ggcctggggg aatcccgcat cggcaagttt tttcattttc agtaagccct gttttgccgc
    22621 cagtcgcggg ttagacacct gaaaacggtg acgggtagag gcttcattac caaacgacag
    22681 gcccgcgtaa tggtgcgtca gccctaccag cccgtcgaaa ttgacttccc aggcgttcat
    22741 cgcaccacct catcggaaaa atccagcccg gggttaagcg ttgcgggcaa cgttaacgag
    22801 tccgactcca gacttgccat cggccaggca caataatctg cggcatacca ggcgctgggg
    22861 cgatgattgc cggaagcgcc aatgccgccg aatggcgcgg tactggcagc accggtaagc
    22921 ggtttgttcc agttaacaat ccccgcccgt gcctccagca acagttgatc gaatttttcc
    22981 cgctcggggg aaaccagacc gcaagagagg ccgaagcgag tgttattcgc cattcgaatc
    23041 gcttcatcga aattgtcata acgccagacg cgcaataacg gcccaaacac ttcttcatcc
    23101 ggcacgccag taacgcctgt catttcaatg atccccggcg tcagcaacga tgtccctgct
    23161 tgtaataagc gcggcgcaag caggggccgt ccgcccatcg cctccagttc ctgccaggca
    23221 gtaaccacct gctgtgcggc ctgctcagaa atcagcccgc caataaacgg ctgcggttcg
    23281 tcatcccaag tgcccggcgt taaccgctgg ctgacggcaa ccaggcgagc aagaaatgca
    23341 tcgccctgcg ttccactttt cagcaataaa cggcgggcgc aggtgcagcg ttgcccggca
    23401 gtgacaaacg ccgactgaat ggtcagatgg acagcggcat cgatatccgc cacctcatcg
    23461 ataattagcg ggttattacc gcccatctca agggcgagaa ttttctccgg ctgaccggaa
    23521 agctggcgat gcagctggta gccggtattg gcgctgccgg taaacagcaa accgtcgaga
    23581 tcctccagcg cactcagcgc ctgacccgtt tcacgcccgc cctgcaccag gttcagcacg
    23641 cccggcagca agccagcctg ctgccataaa cgcattaccg cttcgccact ccacggtgtc
    23701 agttcgctgg gtttaaaaat aatggtgtta cctgccagca atgccggaac aatatgtccg
    23761 ttcggcagat gaccagggaa attatacggt ccaaacactg ccagtacgcc gtgcggacga
    23821 tggcgcaagc tcgccgcgcc gtccggcatt tcgctacgct gctcaccggt acgaacgtga
    23881 tacgccttaa ttgatatcgc gattttattg atcatcgccg tcacttcggt tgccgcttcc
    23941 cagcgcggct tgccggtttc tctggcaata atcgcggtta attcagcttt attgctttcc
    24001 agcaatccgg caaagcgttc aactcttacc tgacgatcgc taaatgagag cctcgcccag
    24061 cgcggaaacg ccgctcgggc agcccgacaa gcctgctcga cctgagcagc atcggcatca
    24121 ttgccctgcc ataacacctc gcccgatacc ggattacgct tcacacgcaa tgcgccctgg
    24181 cccgttaccc agtcaccgtt aatccataaa gtcatgctgt tttctcctct gcgcacaggc
    24241 gcaccagacg aacgcgatcc cctgcgtggc atttgagggc atccagttgt gcggcggtta
    24301 aaatcaaacg ctcggtcgct ggatcggtac gcaccagcac cacgcggaaa tggtgataat
    24361 tttcattggc gaccaggcag gccggaaaat cgccctgcgc aggctgccct tcggccactt
    24421 ccaccagccg acttttacgg atggcgcgca cgcggtcgat atcacactca agtgtcggcc
    24481 cgccgtcaaa gatgtcgata tagttacggt agcgaaaacc ttctttctcc agcaccgcac
    24541 gggcaggtgc ggtttgcgga tgtacctgac cgatgacgtc ctgtgcttcc tgggataaaa
    24601 agtgcgtata gatcggatgt ttcggcatca gttctgcaat aaatgccttt tgcccggtgc
    24661 cgcagagaaa atcagcgcgg ctaaaatcca tcgaaaagaa gcgtttaccg aggctttgcc
    24721 agaacggtga atagccgtgt tcgtcaatca ccccgcgcat ttcggcgacc actttgtcat
    24781 taaacttgtc gcgaaaagcc gccataaaca taaagcgcga tttcgacagc aaatagccgt
    24841 tgccctcttt gcgccactcc gggtcgagaa acagcgtgca cagctcgctg ctgccggtgt
    24901 gatcgttact gagaaacagc gtcggcaatg cgttatagac attcagctct ttcgaagcgt
    24961 gaaccagcgt gccgacgcga tagttgtacc agggatcgtt cagcccaacc gccacctcaa
    25021 tggcgcaaat ccccgccaca gtgcctgact cgctatcttc cagtacaaac acataaccct
    25081 gctcactttt gggcagttcg ccttgccagg ttttgattgc cctttcaata cgcaccgaaa
    25141 gcgtggcttc attggcggga agcgacgtca ggccgccgcc cgttttgctg gcaagctgca
    25201 tcagcgccga gacatctgag cgctcaacgg gacgaatgac catcatgatg aacctcggct
    25261 aacaaagtgt tcgcaagcag ctgcaaagcg ctccagtccg gtcgtcacct cttcttcgct
    25321 gacattgagc gctggcgcaa aacgcaccac gttgccaccc gcaatcagca ccatcacgcc
    25381 tgctttcgcc gcttcctgag agagctgttt cgcttgcccg gcgtaatcgg cattcagtac
    25441 acagccaatc aaaagaccta agccgcgaac ttcactgaac aaactgtagt ggtgattaat
    25501 ggaatttaga cgctcaacaa accagtcgtg acgctgttta accccgttaa gcatctctgg
    25561 cgtgttgatg agatccagca ctttgcctgc caccgccgag gccagcggat tgccgccata
    25621 ggtggtgccg tgagtgccaa cggtcatcac gctggcgcac tcttcggttg ccaacaacgc
    25681 accaaccggg aaaccgccgc ccagcgcttt ggcggtagtt aacagatcag gcgtcacgcc
    25741 gtagtgcata taggcataca gttccccggt gcgcccgaca ccggtttgta cttcatcaaa
    25801 gataagcaac gcattgtggc ggtcacacaa ttcacgcaga ccttgtaaaa atgcgttgct
    25861 ggctggcacc acaccgcctt ccccctggat gggttcgaca atcaccgcac aggtggcgtc
    25921 gtcaatcagc gcactggcag agttaatatc gttatatgca gcatgacgaa tatccggcgg
    25981 cagtggcgca aaatcctgtg aataggctgg ctgcccaccc gcactgacag taaacagcgt
    26041 gcgaccatga aacgcatttt tgaacgccac gatgccgctc ttatggctgc cgtagcggtc
    26101 gtgagcgaat ttacgcgcca gttttagcgc cgcttcgttg gcttccgcac cggagttaca
    26161 aaagaagacg cgatcggcaa acgtggcgtc gatcaatttt ttcgccagtc gcagtaccgg
    26221 ctcgttggtg taaccgttgc cggtatgcca gaacttactc gcctgttcgt tcagcgcctc
    26281 acgcagttcc ggatgcgcat ggcccagcgc gttcaccgca atgccacccg cgaagtcgat
    26341 atactctttc ccctgctgct cccacaagcg cgaaccttcg ccacgtaccg gtataaacgg
    26401 tgccggagcg taaacaggta tcatccattc atcaaagttt tcac
//
LOCUS       DAFGPF010000066        26372 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFGPF010000066 DAFGPF010000000
VERSION     DAFGPF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26372
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.066"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..165
                     /locus_tag="LSX49_003054"
     CDS             <1..165
                     /locus_tag="LSX49_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL7169434.1"
                     /translation="YTRQGYAIEAITATIDWIKENGFSLIKAGVNPENTLSKKLLIRI
                     GFNFSSIEDG"
     gene            542..799
                     /locus_tag="LSX49_003055"
     CDS             542..799
                     /locus_tag="LSX49_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjhX family toxin"
                     /protein_id="HBL7169435.1"
                     /translation="MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLT
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQLDNR"
     gene            811..1362
                     /locus_tag="LSX49_003056"
     CDS             811..1362
                     /locus_tag="LSX49_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL7169436.1"
                     /translation="MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDES
                     ARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMHILAPLAVIPEYQGMGVGGRLIR
                     TGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
                     QPMNVTGHIQCAQALMKPEHWRE"
     gene            1414..2160
                     /locus_tag="LSX49_003057"
     CDS             1414..2160
                     /locus_tag="LSX49_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL7169437.1"
                     /translation="MDIPRIFTISESEHRIHNPFTEEKYATLGRVLRMKPETRILDLG
                     SGSGEMLCTWARDHGITGTGIDMSSLFTAQARRRAEELGVSERVHFIHNDAAGYVANE
                     KCDVAACVGATWIAGGFAGTVELLAQSLKPGGIMLIGEPYWRQLPATDEIAQACGVSS
                     TTDFLTLPGLVSAFDDLGYDVVEMVLADQEGWDRYEAAKWLTMRRWLEANPDDDFAAE
                     VRAELNISPKRHVTYAREYFGWGVFALIAR"
     gene            2288..2548
                     /locus_tag="LSX49_003058"
     CDS             2288..2548
                     /locus_tag="LSX49_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169438.1"
                     /translation="MSQHEQFCQACGMPMSAPDAHSASDQYCAYCSDSNGNLKPWEEA
                     VSGLASFLDSWQKVGPEEAHKRAKRYLTAMPAWAHKAESDLS"
     gene            2586..2702
                     /locus_tag="LSX49_003059"
                     /pseudo
     CDS             2586..2702
                     /locus_tag="LSX49_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227376.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            2947..4068
                     /locus_tag="LSX49_003060"
     CDS             2947..4068
                     /locus_tag="LSX49_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418725.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBL7169439.1"
                     /translation="MSFSVQETLFSLLQHNAISGHENAVADVMLCEFRRQAKEVWRDR
                     LGNVVARYGSDKPDALRLMIFAHMDEVGFMVRKIEPSGFLRFERVGGPAQVTMAGSIV
                     TLTGDKGPVMGCIGIKSYHFAKGDERTQSPSVDKLWIDIGAKDKDDAIRMGIQVGTPV
                     TLYNPPQLLANDLVCSKALDDRLGCTALLGVADAISTTELDIAVYLVASVQEEFNIRG
                     IVPVLRRVKPDLAIGIDITPSCDTPDLHDYSEVRINQGVGITCLNYHGRGTLAGLITP
                     PRLIRMLEQTALEHNIPVQREVAPGVITETGYIQVEQDGIPCASLSIPCRYTHSPAEV
                     ASLRDLTDCIRLLTALAGMSAAHFPVEPDSGTTQEAHPL"
     gene            4065..4343
                     /locus_tag="LSX49_003061"
     CDS             4065..4343
                     /locus_tag="LSX49_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL7169440.1"
                     /translation="MKKILVACGTGMSTSTMIAHKLQEFLTEQGISATTAQCCLNEIP
                     LNCNGMDLIVTSMRTNSDYGIPTLNGAALLTGINDDALKQQIKALLTQ"
     gene            4355..5668
                     /locus_tag="LSX49_003062"
     CDS             4355..5668
                     /locus_tag="LSX49_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL7169441.1"
                     /translation="MFDYILSLGGTVFVPIIMIVIGLIFRIPWLQAIKAGVTVGIGFV
                     GMGLVIVMAIDSLSPPIKVMIERFGLALHVFDVGAGPASGVGYATAIGAMIIPVIFLL
                     NVAMLVTRLTKTMNVDIYNYWHYAITGTVVQLMTGSLIYGVLGAICHAALSLKMADWT
                     AKRVQNIVGLEGISIPQGYGSSSVPLFVLLDAIYEKIPFMKGRNIDAQEIQKRYGMVG
                     DPVIIGVVLGLIFGLAAGEGFKGCASLMITVAAIMVLFPRMIRLIVEGLMPISDGARK
                     FFQKYFKGREVYIGLDTAVTLGHPTTIAVGLLLIPIMLILASILPGNKVLPLADLPVA
                     PFFICMATVIHRGDLVRTLISGVIVMITVLLIATQFAPYFTEMALKGGFSFAGESAQI
                     SALSVGNMFGWSISELMSLGIIGVVVAVGIVASVVLFLRKRELSE"
     gene            5681..6487
                     /gene="sgcQ"
                     /locus_tag="LSX49_003063"
     CDS             5681..6487
                     /gene="sgcQ"
                     /locus_tag="LSX49_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA family protein SgcQ"
                     /protein_id="HBL7169442.1"
                     /translation="MSWLKEVIGTEKAVIAMCHLRALPGDPSFDAQLGMNWVIDKAWD
                     DLMALQNGGVDAVMFSNEFSLPYLTKVRPETTAAMARIIGQLMSDIRIPFGVNVLWDP
                     VASFDLAMATGAKFIREIFTGAYASDFGVWDTNVGETIRHQHRIGAGEVKTLFNIVPE
                     AAVYLGNRDICSIAKSTVFNNHPDALCVSGLTAGTRTDSALLKRVKETVPDTVVLANT
                     GVCLENVEEQLSIADGCVTATTFKKDGVFANFVDQARVSQFMEKVHHIRR"
     gene            6618..7049
                     /locus_tag="LSX49_003064"
     CDS             6618..7049
                     /locus_tag="LSX49_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL7169443.1"
                     /translation="MINDIKWVQAQREATDWRQAVEIATRPLVAYGAAQPCYVNGIIE
                     NTLNWGPYYLIAPGIALPHARPEQGANYNQVSITTLRTPVAFGNEECDPVWLLLCVSA
                     TDANAHILTIQRISQFIDSPQRLAAVGNASTDDALFALVSG"
     gene            7061..7693
                     /locus_tag="LSX49_003065"
     CDS             7061..7693
                     /locus_tag="LSX49_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3 epimerase family protein"
                     /protein_id="HBL7169444.1"
                     /translation="MILHPSLASANPLHYGRELTALDNLDFGSLHLDIEDSSFINNIT
                     FGMKTVQAVARQTPHPLSFHFMVARPQRWFNALAEIRPAWIFVHAETLDYPSETLTEI
                     RHTGARAGLVFNPATPIDAWRYLASELDGVMVMTSEPDGQGQRFIPSMCEKIQKVRTA
                     FPQTECWADGGITLAAAQQLAAAGAQHMVIGRALFSSSDYRATLAQFATL"
     gene            7710..8492
                     /locus_tag="LSX49_003066"
     CDS             7710..8492
                     /locus_tag="LSX49_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7169445.1"
                     /translation="MSQQRPDRIKQMLHYLWQHRHLSTQQAMELFGYAEATVRRDFQY
                     IANQYPGMIRGHGCLDFDDSTDDKEYVFDVKRTLQSVAKREIAALARTMIKDGDCFFL
                     DSGSTCLELAKCLADARVKVICNDIKIANELGCFPHVESYIIGGLIRPGYFSVGESLA
                     LEMINAFSVERAFISCDALSLETGITNATMFEVGVKTRIIQRSREVILMADHSKFDAV
                     EPHAVATLSCIKTIISDSGLPETIAQRYQRAGCQLFLPHSIK"
     gene            8795..9583
                     /locus_tag="LSX49_003067"
     CDS             8795..9583
                     /locus_tag="LSX49_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBL7169446.1"
                     /translation="MVRKGCNSLVRAEKILTHIAWVGMASYMELLNKFQYPKSSLLNL
                     LNVMVECGFLIKNKNGYYSLGIKNYELGCQALHRQNIFEVTKRPMQELSLKSGLVCHL
                     GAMESISAIYLDKIESPDSVPTSKSWIGKKIELHITALGKALLAWKTREELDYFLEAL
                     TLTPHTRNTFTDKKLFLEELQKTRLRGWAIDNEESTYGAVCLSMPVFNMYNRVNYAIS
                     LSGDPVVYSGNKIDSYLELLRKCAEQISYGLGYRNENEHLRKGN"
     gene            9588..10493
                     /locus_tag="LSX49_003068"
     CDS             9588..10493
                     /locus_tag="LSX49_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418718.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBL7169447.1"
                     /translation="MKKFSGIIPPVSSTFHRDGTLDKKAMREVADFLINKGVDGLFYL
                     GTGGEFSQMNTAQRMALAEEAVTIVDGRVPVLIGVGSPSTDEAVKLAQHAQAYGADGI
                     VAINPYYWKVAPRNLDDYYQQIARSVTLPVILYNFPDLTGQDLTPETVTRLALQNENI
                     VGIKDTIDSVGHLRTMINTVKSVRPSFSVFCGYDDHLLNTMLLGGDGAITASANFAPE
                     LSVGIYRAWREGDLATAATLNKKLLQLPAIYALETPFVSLIKYSMQCVGLPVETYCLP
                     PILEASEEAKDKVHVLLTAQGILPV"
     gene            10504..12471
                     /gene="yjhG"
                     /locus_tag="LSX49_003069"
     CDS             10504..12471
                     /gene="yjhG"
                     /locus_tag="LSX49_003069"
                     /EC_number="4.2.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylonate dehydratase YjhG"
                     /protein_id="HBL7169448.1"
                     /translation="MSVRNIFADESHDIYTVRTHADGPDGELPLTAEMLINRPSGDLF
                     RMTMNAGMGWSPDELDRDGILLLSTLGGLRGADGKPVALALHQGHYELDIQIKAAAEV
                     IKANHALPYAVYVSDPCDGRTQGTTGMFDSLPYRNDASMVMRRLIRSLPDAKAVIGVA
                     SCDKGLPATMMALAAQHNIATVLVPGGATLPAKDGEDNGKVQTIGARFANGELSLQDA
                     RRAGCKACASSGGGCQFLGTAGTSQVVAEGLGLAIPHSALAPSGEPVWREIARASARA
                     ALNLSQKGITTREILTDKAIENAMTVHAAFGGSTNLLLHIPAIAHQAGCHIPTVDDWI
                     RINKRVPRLVSVLPNGPVYHPTVNAFMAGGVPEVMLHLRSLGLLHEDVMTVTGSTLKE
                     NLDWWEHSERRQRFKQLLLDQEQINADEVIMSPQQAKARGLTSTITFPVGNIAPEGSV
                     IKSTAIDPSMIDEQGIYYHKGVAKVYLSEKSAIYDIKHDKIKAGDILVIIGVGPSGTG
                     MEETYQVTSALKHLSYGKHVSLITDARFSGVSTGACIGHVGPEALAGGPIGKLRTGDV
                     IEIKIDCRELHGEVNFLGTRSDEQLPSQEEATAILNARPSHQDLLPDPELPDDTQLWA
                     MLQAVSGGTWTGCIYDVNKIGAALRDFMNKN"
     gene            12578..13927
                     /locus_tag="LSX49_003070"
     CDS             12578..13927
                     /locus_tag="LSX49_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBL7169449.1"
                     /translation="MPLIIVVAGIALLLLLTIKIKLNTFVSLIIVSIAVAIASGMDLS
                     KVVTSVESGLGGTLGHIGLIFGFGVMLGRLLADAGGAQRIALTMLNYFGKNKLDWAVV
                     CSAFIVGIALFFEVGLILLVPILFAIAREAKISPMFMCVPMLSGLLVAHGFLPPHPGP
                     TVIAREYGADVGLVLIYGIIVGIPTFILCGPVLNKFCQRIIPDAFKKEGNIASLGATR
                     RFSESEMPGFGISFLTAMLPVILMAVVTIIQMTHAKSAADSGLFYNVILFLGNSTIAM
                     LISLLFAIYTMGLGRGKTIPDLMDSCGKAIAGIAGLLLIIGGGGAFKQVLIDSGVGQY
                     ISTLVSGMDINPILMAWGVAAFLRICLGSATVAAISTAGLVIPLLAVHPNTNLALITL
                     ATGAGSCICSHVNDASFWMIKDFFGLTTKETLLSWTLMSTLLSISGLIFILLASLVL"
     gene            14274..15260
                     /locus_tag="LSX49_003071"
     CDS             14274..15260
                     /locus_tag="LSX49_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBL7169450.1"
                     /translation="MDRDQTNSSLFNDDPVLHATWLYYQEGKSQTEVAAIMGVSRVTV
                     VKYLQTARENGLVHINLDVNVFGSIDAALQIRDKFNLQRVIIVPDGEHAGKRDDTKLM
                     RTRLSRAGGMYLNQVIENGDVLGVAWGRTIHQMSKTMTPKSCKNVTVIQMLGSMPSQP
                     DLTIIESSSQIAYKLSGRVASLHVPAVVSSARLAMELQAEPIIRSNFDVLTRCTKAFF
                     VVGNALDENPLIRVGVLNKKEMQTYRDLGAVGVICGRFYDKEGMPVVADVDQRILGIS
                     LAQLRQIERKIFLAGGERGYDATLGALLGGYVTDLIVDEGTAEFLLACELPH"
     gene            complement(15301..16305)
                     /locus_tag="LSX49_003072"
     CDS             complement(15301..16305)
                     /locus_tag="LSX49_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug DMT transporter permease"
                     /protein_id="HBL7169451.1"
                     /translation="MFIVESYAVAIIMCFITMICWGSWANTTKLVSNKKWEFPLFYWD
                     YSIGLLLCSLLFAFTLGSMGEAGRSFIPDIQQASSSSLMSAILAGIIFNISNILLVAS
                     INLAGMAVAFPVGVGLALALGVITTYIGNPQGDPLILFLGVACVVSAIIFTAIAYGRV
                     TQEADKSRRNKGLITAILAGIIMGWFFRFLADSMSDNFSQPASGLMTPYSALVLFAVG
                     LFLSNFVLNTLVMKKPISGEPVNGKMYFSGSLRDHVCGWLGGMIWCVGLAFSLIASGQ
                     AGYAISYGLGQGATMIAVIWGVFIWREFASAPAGTNKLLLTMFISYIVGIVLIIAANQ
                     "
     gene            complement(16409..17050)
                     /locus_tag="LSX49_003073"
     CDS             complement(16409..17050)
                     /locus_tag="LSX49_003073"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HBL7169452.1"
                     /translation="MERIKLAEKIISTCREMNASGLNQGTSGNVSARYTGGMLITPSG
                     IAYSKMTPDMIVFVDDKGIPEAGKIPSSEWLFHLACYKARPELNAVIHTHAVNSTAVA
                     IHNHSIPAIHYMVAVSGTDHIPCIPYYTFGSPELADGVSKGIRESKSLLMQHHGMLAM
                     DVTLEKTLWLAGETETLADLYIKCGGLHHDVPVLSEAEMTIVLEKFKTYGLKA"
     gene            complement(17081..18196)
                     /gene="mtnA"
                     /locus_tag="LSX49_003074"
     CDS             complement(17081..18196)
                     /gene="mtnA"
                     /locus_tag="LSX49_003074"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HBL7169453.1"
                     /translation="MNIKGKHYRTVWVSGDGKAVEIIDQTKLPFKFEVVALTSAEMAA
                     TAIQEMWVRGAPLIGVVAAYGIALGMNHDASDMGLQRYYDLLIKTRPTAINLKWALDR
                     MIDTLKDLCVSERKDVAWALAAEIAEEDVALCEQIGLHGTEVIREIAQKKPAGSVVNI
                     LTHCNAGWLATVDWGTALSPIYKAHENGIPVHVWVDETRPRNQGGLTAFELGSHGIPH
                     TLIADNAGGHLMQHGDVDLCIVGTDRTTARGDVCNKIGTYLKALAAHDNHVPFYVALP
                     SPTIDWTIEDGKSIPIEQRDGKEQSHVYGINPQGELSWVNTAPEGTRCGNYAFDVTPA
                     RYITGFITERGVCAASKSALADMFADLKSKALQGEQH"
     gene            complement(18206..19465)
                     /locus_tag="LSX49_003075"
     CDS             complement(18206..19465)
                     /locus_tag="LSX49_003075"
                     /EC_number="2.7.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000132329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose kinase"
                     /protein_id="HBL7169454.1"
                     /translation="MTDSIPSGYKPLTCDTLPGYLSSRLTPSCEPGGLPEEWKVSEVG
                     DGNLNMVFIVEGTHKTIIVKQALPWLRAGGEGWPLSLSRAGFEYNVLCQEAKYAGHTL
                     IPQVYFYDPEMALFAMEYLTPHVILRKELINGKKFPKLAEDIGRFLAQTLFNTSDIGM
                     SAEQKKALTAEFALNHELCKITEDLIFTEPYYNAERNNWTSPELDDAVHKAWADVEMI
                     QVAMRYKYKFMTEAQALLHGDLHSGSIMVTDTDTKVIDPEFGFMGPMAFDIGNYIGNL
                     LLAYFSRPGWDANEQRRADYQEWLLQQIVQTWSVFTREFRQLWDNKTQGDAWPTEMYQ
                     QNRAALEDAQDQFFATLLEDSLVNAGMEMNRRIIGFAGVAELKQIENTELRAGCERRA
                     LTMARDLIVNARQFKNMDSVIQSAKVK"
     gene            20265..20519
                     /locus_tag="LSX49_003076"
     CDS             20265..20519
                     /locus_tag="LSX49_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000788354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL7169455.1"
                     /translation="MKNGIDVSVIIPAYNAAETSVSLVTKILSEPHLAIELIIVDDGS
                     TDETGNVLRQIHDDRLILIEQANQGVYAARNAALALHQGE"
     gene            21623..23698
                     /locus_tag="LSX49_003077"
     CDS             21623..23698
                     /locus_tag="LSX49_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7169456.1"
                     /translation="MDLVDSVEAGKLTISELIDALAKDKNYSASKWDQRYREFTTLLQ
                     QTSTFSEPETDGLVKRLWYERDNGIASIRQGVPSLAEYQQSLPLLRELTERIRQQPDE
                     ETYQYVGNALQQAKENGLLKRMYRSLRNRVFAAFSPENYTSTVDENAFSKAAEFLNQH
                     FHLGLALTGNWLQKNYELKQAIHAQSPDTDPYYVNMAIWHLYELLRERDNEQKQEKIA
                     STTFITSNEPIENKIILHSPTNVIFFGPPGTGKTFRLQQKMKEYTSHAVPADRDAWLD
                     SRLESLNWMQVITLVLLDLGKRAKVRQIIEHMWFQRKALLNGRNGNLSNTAWAALQSY
                     TVPESLTVDYKNRREPAVFNKTDNSEWLLVDSQLEQVEDLVELYAELKRGPKSAEAIQ
                     RFAVVTFHQSYGYEEFIEGIRARSDESGNISYPIEPGIFMRLSQRANADPGHRYAIFI
                     DEINRGNISKIFGELISLIEVDKRAGMPNAMSLQLAYSGDHFSVPANVDIIGAMNTAD
                     RSLALMDTALRRRFDFVEMMPDLSLLSGAKVKGIELESLLEKLNSRIEALYDREHTLG
                     HAFFMPVKNALDAGDEEAAFKQLKIAFQKKIIPLLQEYFFDDWNKIRLVLADNQKQDD
                     NLQFVIEKTDDLDTLFGNNHGLRHHDQQSTAYELKDFDQEIWNIPQAYRSIYQPQQTP
                     LDEQAVNHG"
     gene            23691..24977
                     /locus_tag="LSX49_003078"
     CDS             23691..24977
                     /locus_tag="LSX49_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBL7169457.1"
                     /translation="MGEVISVFEYDLLGSDKAASVGAKLVPPLVFNYLEALSLASNQG
                     SQFLKLTSRSGFKLLQVQNYAGMLSTPHGFQLEILPKVGKNLTAANARQTLLTMLSHL
                     PGFRHIETQQATLQAQRMPLLEIFIHQFLHSVSQLLKQGLRSDYVSEQGNLAFMKGKL
                     MLSAQLRHNAVNRHKFCVDYDDYMPDCAANRLLHSALDKLLSLKLSSENQRWLYELRF
                     AFDGIPLSRDIERDINNLRLERGMAHYNEPMAWAQLILRGMSPSALQGNTKAISLLFP
                     MEAVFESFVAQTLPYELPSHLKVIPQAATYSLVKHGSNDCFKLRPDLLIQSRRPVQTK
                     LVMDTKWKLINSNSQKTTQYGLAQADFYQMFAYGQKYLNGIGEMYLIYPAHDQFNQPI
                     QQHFAFSKTLKLWVVPYQITANRGERMMWVKDVSSI"
     gene            25087..>26372
                     /locus_tag="LSX49_003079"
     CDS             25087..>26372
                     /locus_tag="LSX49_003079"
                     /EC_number="3.1.21.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Alw26I/Eco31I/Esp3I family type II restriction
                     endonuclease"
                     /protein_id="HBL7169458.1"
                     /translation="MKMGKIAVTPNNDKAASHSKDENLATNTIKKNVKPKYGDAAFLE
                     YTRLIVNHPNYFGMPDPFGEKGEIQWEAPSNRASGKFKHTHQRRYEWWKNKARSIGID
                     PDTEKAWISKTAKLIHPLGVKPCKKCGKEMELSYSYPNEHFFSRVRKLNYIDETFELS
                     QNEHIVDLLTRLDDRFGERIYLDLPHLFSTKSITIPDISSNLEAWIEYLKEQYIPQES
                     RMLSPGAMANPPDRFDGFHSFNRCCRSIADKGRTKENLKSYVTDRRVFEYWVDGDWVA
                     ADRLMGQVRTNNIFINEECLNAGNGGLHPTPCQADHIGPISLGFSHRPQFQLLCKSCN
                     SAKNNRMYLSDIISLLEAENEGHTVISWFAEEVWNRLKHSVDDSEKALRLSKILRDNR
                     HTYMNLLKKIMDEGYYTFLASLLHLEVANYNPIFEG"
BASE COUNT         6927 a         6379 c         6367 g         6699 t
ORIGIN      
        1 tatactcgcc agggatatgc aattgaagca attaccgcca cgattgactg gataaaagag
       61 aacggttttt cactcatcaa agccggtgtg aatccggaaa ataccctttc aaaaaaatta
      121 cttatcagga ttggcttcaa tttttcgagc atcgaagatg ggtgagcata tttatgttct
      181 ggattaaaca aaaggagaat aatctcccga agggaaaagc cgatgaggcc atttcaggcg
      241 tacttcaaca tgcattcgtc agtgtcatct gccttttcca gtaaatgggt tggcattcaa
      301 tttccaaagt acatcacact ttttctactg aaacatatcc ctcctataac tacgtgttaa
      361 tattcgctcc gtaaatacct ttcaactcaa cccgaggctt tgatgctgga gaatgtaatc
      421 atccgataat cagttccccg accttttcag gccggactga ttatcaatgc gccgaaatcg
      481 aatgcggaca ccgcggtgtg tttgcacgtt ttgcacatga tgattaaaca ggttcttcag
      541 tatgaattta tcccgtcagg aacaacgtac gttacacgtt ctcgctaaag gtggacgtat
      601 tgcgcacgtc cgcgattctt caggccgcgt cacttccgtt gaatgctaca gccgcgaagg
      661 gctgttgctg accgactgca cgctcgccgt cttcaaaaaa ctcaaaacca aaaaacttat
      721 caagtccgtc aatggtcagc cctatcgaat caacactacc gggctgaata acgttcgcgc
      781 tcagctcgat aatcgctaag gagagtttcg atgacagcac accacttcac ttttcaaatc
      841 acagatgaaa gtgatgccag tgatatccgg gaagtcgaaa cccgcgcatt tggcttcagc
      901 aaagaagccg atttaacggc ctctttactt gaggatgaaa gcgcgcgccc tgcgttatcg
      961 ctgctggccc gacatgaagg caaagccgtc gggcatattt tatttacccg ggcaaccttc
     1021 aaaggggaaa tggattcacc gctgatgcat atcctcgctc ccctggcagt cataccggaa
     1081 taccagggga tgggcgtggg aggacggttg atacgcactg gcatcgagca cctgaggttg
     1141 atgggctgcc agacggtttt tgttctcggc cacgccacct attacccccg acatgggttc
     1201 gaaccctgtg ccggagacaa aggctatccg gcaccttatc ccatcccgga ggagcacaaa
     1261 gcctgctgga tgatgcaagc actcaccgct cagcccatga acgtgaccgg ccacatccag
     1321 tgcgcgcagg ccctgatgaa accggagcac tggcgtgaat aacaatcttg ttgtgccctt
     1381 tttaatgctt aacccaataa caggaattaa ctaatggata ttccacgtat ttttaccatc
     1441 agtgaaagcg aacaccgcat ccacaacccg ttcaccgaag agaagtacgc cacgctgggt
     1501 cgcgtgctgc gcatgaaacc agagacccga attctggacc tcggcagcgg ctcgggcgag
     1561 atgctctgca cctgggcccg ggatcatggc attacgggga ctggaatcga catgagttcg
     1621 ctcttcaccg cgcaggccag acgccgcgcg gaagaactcg gcgtcagcga acgcgtacat
     1681 tttattcata atgatgcggc gggttacgtc gccaatgaaa aatgtgacgt agcagcctgc
     1741 gttggcgcga cctggattgc cggaggcttt gccgggacag tcgaactgct ggcgcagagc
     1801 cttaaaccgg gcgggatcat gctcatcggt gaaccttact ggcgtcagct tccggcaacg
     1861 gacgagatag cccaggcctg tggcgtcagc tcgacgaccg attttctgac gctaccaggg
     1921 cttgtcagcg cgtttgacga cctcggctac gacgtggtgg aaatggtact ggcggaccag
     1981 gaaggctggg accgatatga ggccgcgaaa tggctgacca tgcgccgctg gctggaggcc
     2041 aatcctgacg atgacttcgc cgccgaagtc agggccgagc taaacatctc gccgaaacgc
     2101 cacgtaacgt acgcgcggga atactttggc tggggcgtgt tcgcactcat cgctaggtaa
     2161 caacaggttc ccggtatttc tgactggaga taccgggggc ttagcctttg ctttaatctg
     2221 atgcatcacc tgcacaatac atattcagta tgtttattaa tcaagatgtc accataagga
     2281 gcatcatatg tcacaacatg aacagttctg tcaggcttgc ggaatgccga tgtcggcacc
     2341 agatgcacac agtgccagtg atcaatattg tgcgtactgc agcgacagca acggcaatct
     2401 caaaccctgg gaagaggcgg tatcaggttt agccagcttc cttgattcct ggcaaaaagt
     2461 cggcccggag gaagcacata agcgtgcaaa acgttatctg acggcaatgc cagcctgggc
     2521 tcataaagcg gagagtgatt tgagctgatt atctatactc cctctgaatc tattcaggag
     2581 atccgatgtt ttcttacatt atgctgggaa ccaacgacct gccacgcgcc attacattct
     2641 aagatccgct gatggagatg ctggggtatc cacgtgcagg acgtaatgaa gagggagcgt
     2701 cctgcaacaa agtggtgcga taacagttac cgcgttttat tcattctcat tatttcaacc
     2761 ataatcactg gtctctctag cccgtaactt tcacaaacgt tgagcgcttt tattccactc
     2821 ggctcacata attttttatt tgttcagctt tgcgcgtttt cacgtgaacg ttctcacaat
     2881 tattcgacca gtctgcgcct ataaaacgct caacgagtga ttgttttacg gtctacggag
     2941 atagctatgt cattttctgt gcaggaaacc ctgttctcgc ttttgcagca caatgcgatt
     3001 tcaggacacg aaaacgctgt cgctgacgtc atgctgtgcg aattcaggcg tcaggcaaaa
     3061 gaggtctggc gagacaggct tgggaatgtc gtcgcgcgct acggtagtga taaacccgat
     3121 gcgctgcgac tgatgatttt tgcgcatatg gatgaagtcg gttttatggt gcgcaaaata
     3181 gagccttctg gatttttacg ctttgaacgc gtaggcggtc ctgcgcaggt cactatggct
     3241 ggatccatcg tcaccctcac cggggacaaa gggccagtca tggggtgtat cggcattaag
     3301 tcctaccact ttgccaaagg cgacgagcgc acgcagtcac cttctgtcga caaactgtgg
     3361 attgatattg gtgccaaaga caaagacgac gctatacgaa tgggcattca ggtcggtacg
     3421 cctgtcactc tgtataaccc gccgcaactc ctggcaaacg atctggtgtg cagtaaagca
     3481 ctagacgatc gtctgggctg tactgccctg ctcggtgtag cggatgctat cagtactacg
     3541 gagcttgata tcgccgttta tctggtggct tcggtacagg aagaatttaa tatccgcggc
     3601 attgttcccg tattacgccg tgtaaaacct gacctggcga ttggtattga tatcactcca
     3661 tcgtgtgaca cccctgattt acacgattat tccgaggtca ggattaatca gggcgttggg
     3721 atcacctgcc tgaactacca tggtcgggga acgctggccg gattaatcac gcctcctcgc
     3781 ctgatacgga tgttggaaca gacggctctt gaacacaaca ttccggtgca gcgagaagtg
     3841 gctcccggcg tgataacaga aaccggttat atccaggttg agcaggatgg tattccctgc
     3901 gccagtctct ctattccttg tcgctatacc cattctccgg cggaggttgc cagcctgcgt
     3961 gatttgactg attgcatccg cctattgacc gctctggcag gtatgtcagc agcacatttc
     4021 cccgttgagc ctgattcagg cactacacaa gaggcacatc cattatgaaa aagatccttg
     4081 tggcatgcgg taccggcatg tcgacttcaa ccatgattgc acacaagctg caagagttcc
     4141 tgactgaaca gggcatttca gccactaccg cccaatgctg tctgaatgag atccctctta
     4201 actgtaacgg tatggacctt attgtaacct ccatgcgaac caacagtgat tacggcatcc
     4261 ctacgcttaa tggcgccgcc ctgctcacag ggatcaacga cgacgcgtta aaacaacaaa
     4321 tcaaggctct gttaactcaa taaaaggagg cattatgttt gattacatcc tgtctctcgg
     4381 cggtaccgtt ttcgtcccta tcatcatgat cgtgattggc cttatcttcc gcatcccctg
     4441 gctgcaggcg attaaggcag gggtaacggt tgggattggt tttgtcggta tgggactggt
     4501 gatcgtcatg gcgatcgaca gcctcagtcc ccctatcaaa gtgatgattg agcgtttcgg
     4561 cctggccctg catgtctttg acgttggcgc aggccctgcc tccggcgttg gttatgcgac
     4621 agccattggc gccatgatta tcccagttat ttttcttctc aatgtcgcca tgctggtcac
     4681 ccgtctgacc aaaacgatga acgtcgatat ttacaattac tggcactacg ccattacggg
     4741 tacggtggtc cagcttatga ccggtagcct gatttatggt gtgctggggg caatctgcca
     4801 tgcggcgcta tcgttaaaaa tggccgactg gacggcaaaa cgggtacaga acatcgtcgg
     4861 gctggaaggt atttcgatac cgcaaggcta cggttccagt tcagtaccgc ttttcgttct
     4921 acttgatgct atctatgaaa aaatcccttt catgaaggga cgcaatatcg atgctcagga
     4981 gatccagaaa cgctacggca tggtcggcga tccggtgatt atcggcgtag tgctcggtct
     5041 gatttttggc ctggcggctg gtgaaggctt taaaggttgc gccagtctga tgattaccgt
     5101 tgcggcaatc atggtgctgt tcccgcgcat gatccgcctg attgttgagg gcctgatgcc
     5161 catctccgac ggtgcaagaa agttcttcca gaaatatttc aaaggacgtg aagtgtatat
     5221 cggtctggat actgctgtga cgctggggca tccaaccacc attgctgtcg gtctgctact
     5281 gatacccatt atgttaattc tggccagcat tttaccgggc aacaaagtgt tacccctcgc
     5341 agacctgccg gtagcaccgt tctttatctg tatggctacg gttatccacc gcggagacct
     5401 ggtcaggacg ttgataagcg gggtcatcgt gatgattacc gtcctgctga tcgccaccca
     5461 gttcgcgcct tacttcactg aaatggcgct caaaggcggt ttcagttttg ccggtgaaag
     5521 tgcgcaaatc tcagcgttgt ccgtgggcaa tatgttcggt tggtcgattt ctgaattgat
     5581 gtcgcttggg attattggcg ttgtcgtggc ggtcggtatt gtcgccagcg tcgtgctgtt
     5641 cttacgtaaa cgtgaattat cggaataagg agtactttca atgagttggc tgaaagaggt
     5701 tattgggacg gaaaaagcgg tcatcgccat gtgccatcta cgtgcattgc ccggcgaccc
     5761 gagttttgat gcgcagttgg ggatgaactg ggttatcgac aaagcctggg acgatctgat
     5821 ggcgctccaa aatggtgggg tggatgcagt catgttctcc aacgagttta gtcttcccta
     5881 tctcacgaag gtgcgtccgg aaaccactgc ggcaatggca cgaatcatcg ggcaattaat
     5941 gagcgatatc cgcatcccgt ttggcgtgaa tgttctgtgg gatccggtcg cctcattcga
     6001 cctggcgatg gctaccggcg ctaagtttat ccgcgagata tttaccggtg cctatgccag
     6061 cgactttggc gtctgggaca ctaacgtcgg tgagaccatc cgtcatcaac accggattgg
     6121 tgcaggcgaa gtgaaaacct tgttcaatat cgtcccagag gccgccgtgt atctgggcaa
     6181 tcgcgatatc tgttctattg ctaaatcgac agtatttaac aaccatcctg atgcgctctg
     6241 tgtttctggc ctgaccgccg ggacgcgtac agacagcgcg ctgttaaaac gggtcaaaga
     6301 aacggtgcct gacaccgtcg tgttggccaa cacgggcgtc tgcctggaaa acgtggagga
     6361 acaactcagt atcgccgatg gctgtgtgac cgcaaccacc tttaaaaagg acggcgtttt
     6421 tgccaatttc gttgaccagg cgcgagtcag tcagtttatg gagaaagtgc atcatatacg
     6481 ccgataagat agggataagc agagcgctta tccccggcaa agagcaataa cccttctgcg
     6541 atccctgccg ccttcgtcaa aagtatcgac ggggatcgct accagattaa cccgaatcgg
     6601 catggagtca acgacggatg attaacgata ttaaatgggt acaggcacaa cgtgaagcca
     6661 ccgactggcg tcaggccgtg gaaatcgcca cccgcccgct ggtagcctat ggtgccgcgc
     6721 agccatgcta cgttaatggg atcatcgaaa atacccttaa ctgggggcct tattatctga
     6781 tagccccagg aatcgccttg cctcacgccc gaccagagca aggcgcaaac tataatcagg
     6841 tcagtatcac cacgctacgc accccggtcg cctttggtaa cgaggagtgc gaccccgtct
     6901 ggctgcttct ctgcgtcagc gccacagatg ccaacgcaca tattttgacc attcagcgca
     6961 tcagccagtt tattgattcg ccacaacgct tagcggcagt gggaaatgcc agcacagacg
     7021 atgcactgtt tgcgctggta tcaggttaac ggaggcgctt atgatcctgc acccttctct
     7081 cgccagcgca aatcctctgc actatggtcg tgagctgacg gcattggaca atctggattt
     7141 tgggagcctg catctggata ttgaggacag cagcttcatt aacaacatta cgtttgggat
     7201 gaaaacggtg caggccgtcg ccagacagac gcctcatccc ttgtcctttc atttcatggt
     7261 tgcccggcca cagcgctggt ttaacgcgct ggctgaaatc agacccgcgt ggatcttcgt
     7321 tcatgcagaa acgctggact atccttcgga aacgttaact gagatccgcc ataccggcgc
     7381 acgagccgga ctggtattta atccggcaac cccgatcgac gcctggcgat atctggcgtc
     7441 tgagctggac ggagtgatgg tgatgaccag tgagcccgat gggcagggac agcggtttat
     7501 tccctccatg tgcgagaaaa tccaaaaagt acgcacggct tttcctcaga ccgagtgctg
     7561 ggccgacggt ggaattacgc tggcagctgc acagcaactg gcagcagccg gggcgcaaca
     7621 tatggtgatt gggcgcgccc tgttctcttc atctgactat cgcgcgacct tagctcaatt
     7681 cgccaccctg taagaggaga ttgtttctga tgagccaaca gagacctgac cgtatcaaac
     7741 agatgctgca ctacctgtgg caacatcgtc acctctccac acagcaggcc atggagcttt
     7801 ttggctatgc ggaagcgact gtccgtcgtg atttccagta tattgccaac cagtatccag
     7861 gcatgatccg cggtcacggt tgcctggact tcgacgacag tacagacgac aaagagtacg
     7921 tcttcgacgt gaaacgtaca ttgcaatctg tggcgaaaag agaaatagct gcccttgccc
     7981 gaacaatgat caaagatggc gactgctttt ttctcgactc cggctcaacc tgcctcgaac
     8041 tggcgaaatg cctggccgat gcgcgggtaa aggtcatctg caacgacatt aaaatcgcca
     8101 atgaactggg ctgttttccc catgtggaaa gttacattat cggaggactg attcgcccag
     8161 gttatttttc ggtaggagag agtctggcgc tggagatgat caatgccttt tccgtagaac
     8221 gtgcgtttat ctcctgcgat gcgctgtcgc tggagacggg gatcaccaat gccaccatgt
     8281 ttgaggtcgg ggtgaaaaca cggattattc aacgctcgcg tgaagttatt ctcatggccg
     8341 atcactcaaa atttgatgcc gttgagccgc atgctgtagc aacactatca tgtattaaaa
     8401 cgatcatcag tgacagcggg ttacctgaga ctattgcaca gcgttatcag cgagccggat
     8461 gtcagttgtt tttacctcat tcaataaagt gataagtaag ttcgttcgag agggatttca
     8521 agcaaaaata atcaatggca cccaatagaa aatattggcg atgcgctcga acgaataaag
     8581 aagccctatg cgcaatccac acgctacgat gttgcaacaa cacgccatct actttttatt
     8641 ctcattcact aaatgtggtt gttctggatt cattattcaa agtgtgtaca agatcacatt
     8701 taatcacttc attacagttc agcatgctga acaaagcata ttttccacta tgtaatgccg
     8761 ataccattta ttccatgagc aagaaggagc cattatggtt cgcaaagggt gtaattcatt
     8821 agtccgtgct gaaaaaatat taacccacat tgcatgggtt ggtatggcaa gttatatgga
     8881 gttattaaat aaattccagt accccaaaag cagcctgctt aatttattga atgtaatggt
     8941 ggagtgtggt ttcttaatta aaaacaaaaa cggctactat tcactgggaa taaaaaacta
     9001 cgaattgggt tgtcaggcgt tacaccgtca aaatatattt gaggtgacta agcggccaat
     9061 gcaggagttg tcgctgaaaa gtggactggt ttgtcatctt ggggcgatgg agagcatttc
     9121 ggctatctat ctcgacaaga tcgaaagtcc ggactctgta ccgacgagca aaagctggat
     9181 tggcaaaaaa attgagttgc atattaccgc gttgggtaag gcattattag cctggaagac
     9241 acgagaagaa ctggattatt ttttagaagc actcacgtta actccacata cgcgcaatac
     9301 atttaccgat aaaaaattgt ttctggaaga attacaaaaa acacgccttc ggggatgggc
     9361 catagacaac gaagaatcaa cctatggggc ggtatgttta agtatgccgg tattcaatat
     9421 gtataacaga gttaactatg caatctcact ttctggcgat ccggtagttt attcaggaaa
     9481 taagatagac agctatctgg aattgctccg gaaatgcgct gagcaaatat catatgggct
     9541 gggatacaga aacgaaaatg agcatttacg aaaaggaaac tgaggtaatg aaaaaattca
     9601 gcggcattat tccaccggta tccagcacgt ttcatcgtga cggaaccctt gataaaaagg
     9661 caatgcgcga agttgccgac ttcctgatta ataaaggggt cgacgggctg ttttatctgg
     9721 gtaccggtgg tgaatttagc caaatgaata cagcccagcg catggcgctc gccgaagaag
     9781 ctgtaaccat tgtcgacggg cgagtgccgg tattgattgg cgtcggttcc ccttccactg
     9841 acgaagcggt caaactggcg cagcatgcgc aagcctacgg cgctgatggt atcgtcgcca
     9901 tcaaccccta ctactggaaa gtcgcaccac gaaatcttga cgactattac cagcagatcg
     9961 cccgtagcgt caccctaccg gtgatcctgt acaactttcc ggatctgacg ggtcaggact
    10021 taaccccgga aaccgtgacg cgtctggctc tgcaaaacga gaatatcgtt ggcatcaaag
    10081 acaccatcga cagcgttggt cacttgcgta cgatgatcaa cacagttaag tcggtacgcc
    10141 cgtcgttttc ggtattctgc ggttacgatg atcatttgct gaatacgatg ctgctgggcg
    10201 gcgacggtgc gataaccgcc agcgctaact ttgctccgga actctccgtc ggcatctacc
    10261 gcgcctggcg tgaaggcgat ctggcgaccg ctgcgacgct gaataaaaaa ctactacaac
    10321 tgcccgctat ttacgccctc gaaacaccgt ttgtctcact gatcaaatac agcatgcagt
    10381 gtgtcgggct gcctgtagag acatattgct taccaccgat tcttgaagca tcagaagaag
    10441 caaaagataa agtccacgtg ctgcttaccg cgcagggcat tttaccagtc tgaggagaaa
    10501 ctcatgtctg ttcgcaatat ttttgctgac gagagccacg atatttacac cgtcagaacg
    10561 cacgccgatg gcccggacgg cgaactccca ttaaccgcag agatgcttat caaccgcccg
    10621 agcggggatc tgttccgtat gaccatgaat gccggaatgg gttggtctcc ggacgagctg
    10681 gatcgggacg gtattttact gctcagtaca ctcggtggct tacgcggcgc agacggtaaa
    10741 cccgtggcgc tggcgctgca ccaggggcat tacgaactgg acatccagat aaaagcggcg
    10801 gccgaggtta ttaaagccaa ccatgccctg ccctatgccg tgtacgtctc cgatccttgt
    10861 gacgggcgta ctcagggtac aacggggatg tttgattcgc taccataccg aaatgacgca
    10921 tcgatggtaa tgcgccgcct tattcgctct ctgcccgacg cgaaagcagt tattggtgtg
    10981 gcgagttgcg ataaggggct tccggccacc atgatggcac tcgccgcgca gcacaacatc
    11041 gcaaccgtgc tggtccccgg cggcgcgacg ctgcccgcaa aggatggaga agacaacggc
    11101 aaggtgcaaa ccattggcgc acgcttcgcc aatggcgaat tatctctaca ggacgcacgc
    11161 cgtgcgggct gtaaagcctg tgcctcttcc ggcggcggct gtcaattttt gggcactgcc
    11221 gggacatctc aggtggtggc cgaaggattg gggctggcaa tcccacattc agcccttgcc
    11281 ccttccggtg agcctgtgtg gcgggagatc gccagagctt ccgcgcgagc tgcgctgaac
    11341 ctgagtcaaa aaggcatcac cacccgggaa attctcaccg ataaagcgat agagaatgcg
    11401 atgacggtcc atgccgcgtt cggtggttca acaaacctgc tgttacacat cccggcaatt
    11461 gctcaccagg caggttgcca tatcccgacc gttgatgact ggatccgcat caacaagcgc
    11521 gtgccccgac tggtgagcgt actgcctaat ggcccggttt atcatccaac ggtcaatgcc
    11581 tttatggcag gtggtgtgcc ggaagtcatg ttgcatctgc gcagcctcgg attattgcat
    11641 gaagacgtta tgacggttac cggcagcacg ctgaaagaaa acctcgactg gtgggagcac
    11701 tccgaacggc gtcagcggtt caagcaactc ctgctcgatc aggaacaaat caacgctgac
    11761 gaagtgatca tgtctccgca gcaagcaaaa gcgcgcggat taacctcaac tatcaccttc
    11821 ccggtgggta atattgcgcc agaaggttcg gtgatcaaat ccaccgccat tgacccctcg
    11881 atgattgatg agcaaggtat ctattaccat aaaggtgtgg cgaaggttta tctgtccgag
    11941 aaaagtgcga tttacgatat caaacatgac aagatcaagg cgggcgatat tctggtcatt
    12001 attggcgttg gaccttcagg tacagggatg gaagaaacct accaggttac cagtgccctg
    12061 aagcatctgt catacggtaa gcatgtttcg ttaatcaccg atgcacgttt ctcgggcgtt
    12121 tctactggcg cgtgcatcgg ccatgtgggg ccagaagcgc tggccggagg ccccatcggt
    12181 aaattacgca ccggggatgt aattgaaatt aaaattgatt gtcgcgagct tcacggcgaa
    12241 gtcaatttcc tcggaacccg tagcgatgaa caattacctt cacaggagga ggcaactgca
    12301 atattaaatg ccagacccag ccatcaggat ttacttcccg atcctgaatt gccagatgat
    12361 acccagctat gggcaatgct tcaggccgtg agtggcggga catggaccgg ttgtatttat
    12421 gatgtaaaca aaattggcgc ggctttgcgc gattttatga ataaaaactg aaagcataaa
    12481 taaaaacatc cagacacctg aattatccga ctctgcatca ttcgttattt gctcagtcgg
    12541 ataatgatgg gtcgctaccc tgttatgaga ggacgttatg ccactaatta tcgttgtggc
    12601 agggattgct ttactcctgc ttttaaccat aaaaattaag cttaatacgt ttgtttcgtt
    12661 aattattgtc tcgattgctg tcgccatcgc cagtggtatg gatttgagta aagtcgtcac
    12721 ctcagtcgaa tccgggcttg gcggtacgct gggccatatt ggtttgatat ttggcttcgg
    12781 tgttatgctc ggtcgcttgc tggccgatgc gggtggtgcg cagcgaatag cgctgaccat
    12841 gctgaattat ttcgggaaaa ataaacttga ctgggcagtg gtctgttcgg cgtttattgt
    12901 cggtatcgca ctttttttcg aagtcggttt aattcttctg gtacctattt tattcgctat
    12961 tgcccgtgaa gcaaaaatat caccgatgtt tatgtgtgtg ccgatgcttt ctggtttgct
    13021 ggtcgcacac ggttttttgc cgccgcaccc cggcccgact gttatcgcca gggaatatgg
    13081 cgctgatgta ggattggtac tgatatacgg tatcattgtc ggcattccaa cctttattct
    13141 ttgcggcccg gtattgaata aattctgcca gcgcattatt ccggacgcct ttaaaaaaga
    13201 ggggaatata gcctctctcg gcgcgacccg ccgattcagc gaaagcgaaa tgccaggctt
    13261 tgggatcagt tttctcacgg caatgctgcc ggtgatcctg atggcggttg tcaccatcat
    13321 ccagatgact catgccaaaa gtgccgcgga ttctggctta ttttacaacg tgatactgtt
    13381 cttaggtaat tcgacgatcg ccatgctgat ttcactgctg ttcgcgatct ataccatggg
    13441 cctggggcgc gggaaaacaa tccctgacct gatggattct tgcggaaaag ctatcgcggg
    13501 tattgccggt ctgctgctga ttatcggtgg tggtggtgca ttcaagcaag ttctcatcga
    13561 ctctggcgtt ggtcagtata tttccaccct ggtttcgggt atggatatta acccgatctt
    13621 gatggcctgg ggcgtggccg cattcctgcg tatttgtctg ggttcagcca ccgtcgcggc
    13681 gatctctacc gccggtctgg tcatcccatt gttggcagta catcccaata ccaacctggc
    13741 cttgattacg ctggctaccg gtgccggatc ctgtatttgt tctcacgtta acgatgccag
    13801 tttctggatg attaaagact tttttggcct gaccaccaaa gaaacgctgt tatcctggac
    13861 gttgatgtcc acactcttat ccatcagtgg gctgattttt attctgctcg ccagcttagt
    13921 tttataatcg ggttcttgcc agtgagccaa cctgttgttc actgtccccc ataatttagt
    13981 gagtgacggc aaccgtctgc acggtgacga atcgctggcg atcaaaaagg ggcgatattg
    14041 aaccgtcgat tatgcttgat gggtgtactc tcagtaatac tgtaaagccg gagcatgtct
    14101 ccgactttac agtatggggg aacagcaggc gatcgctcaa atggtatgct ggtttatttc
    14161 atgtaaaaga ataaaatatc tgtataaaat catgccactg gcaatctgca tcaactctcc
    14221 gggtaaacag ggttaagatg agcatttccc cggtttaata caggtataca aaagtggata
    14281 gagatcaaac aaacagcagc ctgttcaatg atgatcccgt acttcatgca acatggctgt
    14341 actatcagga aggcaaaagc cagactgaag ttgcagctat catgggggtg tcccgcgtca
    14401 cggttgtcaa atacctgcaa acagcccggg aaaatggact ggttcatatc aacctggatg
    14461 tgaatgtctt tggctctatc gacgctgctt tgcaaattcg cgataaattc aatctccaga
    14521 gagtgatcat cgtgccggat ggcgaacatg ccggaaaacg tgatgataca aagctgatgc
    14581 ggactcgcct ttcacgtgcc ggtggcatgt atctgaatca ggtgattgag aatggtgatg
    14641 tgctgggggt tgcctgggga agaacaatcc atcagatgag caaaaccatg acgccgaagt
    14701 catgtaaaaa tgtcaccgtt atacagatgc tcggttccat gccatctcag ccagacctga
    14761 cgatcattga atcctcatcg caaatcgcct acaagctttc aggccgtgtc gcctcgctgc
    14821 acgtgcccgc cgtggtatca agcgccagac tggccatgga gttacaggca gagcctatta
    14881 ttcgatcgaa ttttgacgtt ctgactcgct gtacgaaagc cttttttgtc gtgggtaacg
    14941 cgcttgatga aaatcccctg attcgggtgg gcgtgctgaa taagaaggaa atgcagacgt
    15001 atcgggattt aggcgcagta ggtgtcattt gtggtcgctt ctatgacaag gaagggatgc
    15061 ccgtcgtggc tgatgttgac cagcgtattc tgggaatcag tctggctcag ctaaggcaga
    15121 ttgaacggaa gatcttcctt gctggtgggg aaagaggcta tgacgcaacg ttgggtgccc
    15181 tgctgggagg atatgtcacg gacctgattg ttgatgaagg aacggcagag tttttgctgg
    15241 cgtgtgaatt accacactaa aagaatgaac aactgcccca tgtggatatg gggcaggatt
    15301 ttattgatta gcggcgataa taagaacaat acccacaatg tatgaaataa acatggtcag
    15361 cagcagttta ttggttccgg ctggcgcact ggcaaattct ctccagatga agactcccca
    15421 gatcacggca atcattgtgg ccccctgtcc cagaccgtag gaaatggcat accccgcctg
    15481 accagacgca atcagactga atgccagacc gacacaccaa atcataccgc ccagccagcc
    15541 gcaaacatga tcccgtaagc tcccggaaaa atacattttc ccgttgaccg gttctcctga
    15601 aataggtttt ttcatgacca gcgtgttaag gacaaagttc gacaagaaca gccccacggc
    15661 aaacagaaca agtgctgagt aaggcgtcat cagaccgctg gcaggctggc tgaaattgtc
    15721 agacatggag tccgccaaga agcggaaaaa ccatcccatg atgatacccg ccagaatggc
    15781 agtaatgaga cctttattac ggcgagattt atccgcctcc tgcgtgacac gaccataggc
    15841 tatcgcggta aaaataatgg cgctcacaac gcaggcgaca ccgaggaaca gaatgagcgg
    15901 atcgccctgc ggattgccga tataggtggt gatcacaccc agagccagtg ccagccccac
    15961 acccacagga aaagctaccg ccataccggc aagattaata gaagcgacca gaagaatatt
    16021 ggaaatattg aagataatcc ctgccagtat tgccgacatc agactactgc tgctcgcctg
    16081 ctgaatatca ggtataaaac tgcgaccggc ttcgcccata gaacccagcg tgaaggcaaa
    16141 taacaaagaa cacagcaata atccaattga ataatcccaa tagaatagag ggaactccca
    16201 ttttttattg ctgacaagtt tagttgtatt cgcccatgaa ccccagcaaa tcatggtaat
    16261 aaaacacatt attatggcga cagcatacga ttccacgata aacataaata actccttgtg
    16321 gtagttataa tcaatcgttg tggacagagg gaatagcagc cattctgcga atggctgtca
    16381 tatgttatta attaaaataa agctgtaatt acgctttcaa accatacgtt ttgaattttt
    16441 caaggacgat ggtcatttcg gcttcagaca gcacgggaac atcgtgatgt aatccgccac
    16501 atttgatgta taaatcagcc agcgtctcgg tttcacccgc cagccacaac gtcttttcca
    16561 gcgtgacgtc catggccagc ataccgtggt gctgcatcag caaggactta ctttctctga
    16621 ttcctttaga tacaccgtcg gccagttcag gactgccaaa ggtataatag ggaatacagg
    16681 gaatatgatc cgtccccgat accgccacca tataatgaat ggccggaatt gaatgattat
    16741 gtattgccac cgccgtggaa ttcaccgcat gcgtatgtat gacagcattc aattctggtc
    16801 tggctttata acacgccaga tgaaataacc attcacttga tggtatttta cccgcttcag
    16861 gtattccctt atcgtctaca aagacaatca tgtccggcgt catctttgaa taagcgatcc
    16921 cactcggcgt aatcaacatg ccaccggtat acctggcact cacattacct gatgttcctt
    16981 gattaagacc tgacgcattc atttcccgac aagtggaaat gattttttct gctaacttaa
    17041 tccgttccat tcctgatcct taatagcaat ggccgccgtt ttaatgctgt tccccctgga
    17101 gtgctttact cttcaggtca gcaaacatat ccgccagcgc tgacttactg gcagcacaga
    17161 ctccccgctc agtaatgaag ccggtaatgt atcgggcagg cgtgacgtcg aaagcgtagt
    17221 tcccacaacg ggttccttca ggggcggtat tgacccagct caattctccc tgagggttta
    17281 tcccatagac atgggactgc tcttttccgt cacgttgctc aatcggaatg ctttttccgt
    17341 cctcgatagt ccagtcaata gtgggagaag gtaacgcgac gtagaaggga acatggttat
    17401 catgggccgc cagcgcctta agataggtac caattttatt acagacatcc cctctggccg
    17461 tggttcgatc ggtcccaaca atgcagagat caacgtcacc gtgttgcatc aggtggccac
    17521 ccgcgttgtc ggcgatcagg gtgtgaggaa taccgtgtga gcccagttca aatgccgtga
    17581 gtccgccctg attacgtggc cgcgtttcat ccacccagac gtgaacaggg attccgtttt
    17641 catgcgcttt gtagatggga gaaagcgcgg ttccccagtc tacagtcgcc agccagcctg
    17701 cgttacaatg tgtcaggata ttgaccacac tcccggccgg ttttttctgg gctatttcgc
    17761 ggatgacttc tgtaccatgt aatccaattt gttcacacaa cgcgacatct tcctcggcaa
    17821 tttctgccgc cagcgcccag gccacatcct tgcgctctga tacacagaga tccttcagtg
    17881 tgtctatcat cctgtcgagg gcccatttga gattaattgc cgttggtcgg gttttgataa
    17941 gaaggtcata gtaacgctgc agacccatgt cactggcatc gtgattcatt cccagcgcga
    18001 tgccataggc tgcaacgaca ccaataagcg gagcgccacg aacccacatc tcctgaatag
    18061 ccgtagcggc catttccgca gaggtaagcg ccaccacctc gaacttaaaa ggcaacttag
    18121 tctgatcgat gatttctacc gcttttccat ccccggaaac ccagaccgta cgatagtgtt
    18181 tacctttaat attcataatg acctcttact taaccttcgc agactggatg acggaatcca
    18241 tatttttaaa ctggcgggca ttgacgataa gatcgcgcgc catggtcaat gcacgtcgtt
    18301 cacatcctgc gcgaagctct gtattttcaa tctgtttcag ctcggcaacg ccagcaaaac
    18361 caatgatccg gcgattcatt tccatgccgg cattcaccag ggaatcttca agcagcgtgg
    18421 caaaaaactg atcctgtgcg tcctcaagag cggccctgtt ctgttgatac atttctgtcg
    18481 gccacgcgtc gccctgtgtt ttgttgtccc agagctggcg gaactcccgg gtgaaaacgg
    18541 accaggtttg gacaatctgc tgaagcagcc attcctgata gtcagcgcga cgttgctcat
    18601 tcgcatccca cccagggcgt gagaagtacg ccagcaggag gttgccaata tagttgccga
    18661 tatcaaacgc cattggcccc atgaaaccga actccggatc aatcactttg gtatccgtgt
    18721 cggtcaccat gattgagcct gaatgaaggt cgccatgtaa caatgcctgc gcttctgtca
    18781 taaatttgta cttataacgc atggcaacct ggatcatctc tacatcagcc caggccttat
    18841 ggacggcatc gtccagctca ggagaagtcc agttattccg ttcagcgttg taatagggct
    18901 ctgtgaagat cagatcttcc gtaattttgc acagctcatg attcaacgcg aactcggcag
    18961 taagcgcttt tttctgttct gctgacatgc caatgtcaga cgtattgaag agagtctgtg
    19021 ctaaaaatct gccgatatct tcagctagtt tagggaattt tttaccgtta atcagttcct
    19081 tacgcagaat cacgtgagga gtcagatact ccatggcaaa cagcgccatt tccgggtcgt
    19141 aaaaatagac ctgcggaatc agtgtgtgac ccgcgtactt ggcttcctga cataagacgt
    19201 tgtactcaaa gcccgcacgg ctcagagata aaggccatcc ttcgccccct gcacgaagcc
    19261 agggcagagc ttgttttaca atgatggttt tatgtgtccc ctcaacgata aacaccatgt
    19321 tcaggtttcc gtcccccact tctgaaactt tccactcttc aggtaaccct cccggttcgc
    19381 atgaaggggt cagtctggac gagagataac ccggcagcgt gtcacatgtc agcggcttgt
    19441 aacctgatgg aattgaatcc gtcataacag ttctccttgt ctacacagaa tgataatcaa
    19501 cttgtcatgt gacaactata cattatcaaa tgtaaaatta tttgtgacac atgtagattt
    19561 tttgaactgt ataatattaa aaatgatgtc gtatggagtc atgatcttta caggaatcag
    19621 cagaggaaaa catctattat taccatgtaa ttcatgttgt tatgtcgcaa caatagtact
    19681 gcacggggaa ttattacggg caaacttagg cgaaaggaag tactgaagtg acagaataaa
    19741 tcacactttt tgtacatatg tacttttcta ttgtcttttg ttgtggaaac aaatagtgtt
    19801 tgtcatgccg atgctaatag acagatagat tcgagggcca acagccccat catcatgatg
    19861 gagcaacaga ggtgagtcta acgtttccgc acttcttatc gatcggcact aacgatcaat
    19921 atcgataaac tgatctatca aaacgattat ctttcttgca acctgcctgg ttatccttct
    19981 cttacattgc tcgcagaaaa gcccttttat tacggttagt tatctagctg agacttgcta
    20041 cgcccatttt ccatgtaccc caaatcacga ggtcacaaag gcgcggaaag atgaagagat
    20101 gtgcacgttg caacaaaaaa agaagcgtcc ttgaacagag gctctcactc gataaagaat
    20161 tctgcgacga gtgcttattc gatatcgatg aggaaatcag ggaaagaagg attatcacga
    20221 tcagacgcct caaagatgac aacgaaagaa aatcgtagct caatatgaaa aatggaatcg
    20281 atgtcagcgt cattatccct gcttacaacg ccgctgaaac cagcgttagt ttggttacta
    20341 aaatcctcag tgaaccccac ttggctattg aacttatcat tgtcgatgac ggttctactg
    20401 atgaaactgg caacgttctt cgtcaaatcc acgatgatcg gctcattctc attgagcagg
    20461 ccaatcaagg tgtctatgcc gcccgaaatg ctgctctagc cttgcaccaa ggagaatagg
    20521 ttatattcct tgatgcggac gacgatatag cagatgggtt catagaaaaa agatggcagg
    20581 cagttagtac gtcgcaagcc gacgtcatga tctttaatgg ctggcattcc tgtgctgacc
    20641 aacatcgaag agcggttcac aaaaagcagc cctatggtac gcctctgtca ggttattaat
    20701 ggattagaca ctgtgttaca caccgcgaat ggccgcatta tctgtggctg cagatggtca
    20761 ggccatccta tgtcaggcag cattcactgc gcttccagtc cggcaggagc cataaagaca
    20821 ttttttaaac ggttcatctt gcagcgagca atggttgatt ctgtacattg gatataaagg
    20881 actatatcta tatcaacaat aaggcctcta tcacacatcg gccggattac tacgttgttc
    20941 gtgctataaa ctatgttgaa gtgatcgcga aaatcatcca agtagcggaa caagaacaaa
    21001 acaaaaaata aaggtatttt tgtaccggca tgcgctggta gaggcacgtc attttttggg
    21061 actctaccgc aatcgcgttg gggataaatc gggcatgaag gactgcttca aagcgaacat
    21121 attcgcagcc catttattca gaggtatcag cagttttagc gatgtgtttt tctttattaa
    21181 gctgctgggc aagctattct gataagttgt gcgttgctac acgacaccag cgcacagctt
    21241 aatttcacgc tttctgacta aattgttcag gccttttcta taggtgcaaa cacaactccc
    21301 cgtactttcc tcttccaact caaaatcatc gcaccttgct gacccaagaa gggagcatac
    21361 cctgcactag tatccgcaca gctaatactc tattgatacc aacaacgctt cagcacaaca
    21421 aagtaactcg ataatcacaa ctcaaagtga agatgccaaa aactcgtttg agagcaataa
    21481 attcaataac atgaaaaaaa tgtattttgc attgaaaatc ttacttattg cgcttggcta
    21541 caattgcatg cttggtaata tagattataa aacaccagac tagctgcctg gtaagtaatg
    21601 taatagcaga ggaaatatca cgatggatct tgtagatagt gtcgaagcag gtaagctgac
    21661 gatcagtgaa ttgattgatg ccctggcgaa agataaaaat tactcagctt ccaagtggga
    21721 tcagcgatac cgtgaattta cgaccttgct acaacaaacc tcaacttttt ctgaacctga
    21781 aacggatggt ttagtcaaga ggctctggta tgaacgcgat aacggtattg ccagtattcg
    21841 ccagggcgtt ccatccttag cagaatatca gcaaagcctg ccactgctta gagaactaac
    21901 tgaacgaatt cggcaacagc cggatgaaga aacttaccaa tatgttggca atgcactaca
    21961 acaagctaaa gaaaacggac ttctcaagcg tatgtatagg agtttgagaa atcgcgtctt
    22021 tgccgcgttc tcgccagaaa actacaccag tactgtggat gagaatgctt ttagtaaagc
    22081 agcagaattc ctaaatcagc acttccatct cggtctggca ctgaccggaa attggttaca
    22141 gaaaaactat gaattgaaac aagccataca cgcccaatct cctgacacag atccttatta
    22201 cgtgaatatg gccatctggc atctctatga attgctccgt gaacgcgata atgaacaaaa
    22261 gcaggagaaa atagcgagca ctacattcat aaccagcaat gagcccatcg agaacaagat
    22321 catcctacat tcaccaacta acgtgatctt ctttggcccc cctggcactg gcaaaacctt
    22381 caggttgcag caaaaaatga aagagtacac ttctcatgct gttccagctg atcgtgatgc
    22441 ctggctggat tctcgccttg aatcgttgaa ttggatgcag gttataacgc tggtgctgct
    22501 cgatcttggg aaacgagcca aagttcgcca aattattgaa catatgtggt ttcaacgtaa
    22561 ggcattatta aacggtcgta atggcaacct atcgaataca gcctgggcag ctttgcaatc
    22621 ctatacagtt cccgagtcgt taaccgttga ttataagaat cggcgtgagc ctgccgtatt
    22681 taacaaaaca gataacagcg aatggttgct agttgattca cagctcgagc aagtggagga
    22741 tttggtagag ctctacgccg aacttaaacg aggccctaaa tctgccgaag ccatccagcg
    22801 ttttgcggtg gttacgttcc accaatctta cggctatgaa gaatttattg aaggtatacg
    22861 cgctcgctct gacgagagtg gcaatatctc ttatcccatt gagccgggta tctttatgcg
    22921 cctttcccaa cgtgccaatg ccgatccagg acatcgctac gccattttca ttgatgagat
    22981 caatcgcggt aacatatcca agatctttgg tgaactaatc tcactcattg aagtagacaa
    23041 gcgtgcaggc atgcccaatg caatgagcct acaactggct tatagcggtg atcacttcag
    23101 cgtacccgcc aatgtcgata tcatcggagc catgaataca gcggaccgtt ctttagctct
    23161 gatggacacg gctttgcgcc gtcgctttga ctttgtcgaa atgatgcccg atctctcttt
    23221 actgagtgga gctaaggtga aaggcataga gctcgagtcg ttgttagaga aactcaatag
    23281 ccgcatcgag gctctttacg atcgtgaaca tacgctgggg catgcgttct ttatgccggt
    23341 aaaaaatgca ctcgatgccg gtgatgaaga agctgcgttt aaacaattga agatcgcatt
    23401 ccagaaaaag atcattccgc ttttacagga atactttttc gatgactgga acaagatccg
    23461 gttggtgctg gcagacaatc aaaagcaaga cgacaacctg caattcgtga ttgagaaaac
    23521 cgacgatctc gatacgcttt ttggtaacaa ccatggttta cgacaccatg atcagcaatc
    23581 aacagcttac gaactcaaag atttcgatca agagatctgg aatattccac aggcttatcg
    23641 ttcaatttat cagccccagc agactcccct tgatgagcag gctgtaaatc atgggtgaag
    23701 ttatctccgt ttttgaatat gacctattgg ggagtgacaa agcggcttca gttggcgcaa
    23761 aactggtgcc tccactggtc tttaattatt tagaagcgct tagcttggca agtaatcaag
    23821 ggagccagtt cctcaaactc acctctcgct caggcttcaa attgcttcag gttcaaaact
    23881 acgcggggat gctttcaaca cctcacggtt tccagcttga gatactgccc aaggttggta
    23941 aaaacctcac agcggctaat gcacgtcaaa cattactgac gatgctaagc catttgcctg
    24001 ggtttcgaca tattgaaact cagcaagcca ctcttcaggc tcagcgtatg cctttgcttg
    24061 agatttttat tcaccagttt ttgcatagcg ttagccaatt acttaaacaa ggtttacgct
    24121 ccgactatgt gagcgagcaa ggtaatctgg cttttatgaa gggcaagctg atgctttctg
    24181 cacagctgcg acataacgcg gtgaatcgcc ataagttttg tgtcgattat gatgactaca
    24241 tgcctgattg tgcagccaat cggctcttac actccgcgct agataagctt cttagtctaa
    24301 agctgtcatc agagaatcaa cgctggcttt acgaactgcg ctttgcgttt gacggtattc
    24361 cacttagccg ggatattgaa cgtgatataa acaacttacg cctcgagcgt ggtatggctc
    24421 attacaacga gccaatggcg tgggcgcaat tgatcctgag aggaatgagt ccgagtgctt
    24481 tgcagggaaa caccaaagcg atatcacttt tgttccctat ggaagcggta tttgaatcct
    24541 ttgtggcaca gaccctaccc tacgaattac cttctcatct caaagtaata ccacaagcgg
    24601 ctacttattc tcttgtgaag cacgggtcta acgattgctt taaacttcgg ccggatttgt
    24661 tgattcagtc acgtcgaccg gtacaaacca aattggtgat ggacacaaaa tggaagctaa
    24721 taaatagcaa ctcccaaaaa acaacacagt atgggctagc gcaagccgac ttctatcaaa
    24781 tgtttgccta cggtcaaaaa tacctaaatg ggattggcga aatgtactta atctatcctg
    24841 cgcatgatca atttaaccaa ccgatacagc agcattttgc tttctctaaa acattaaaac
    24901 tatgggttgt tccgtaccag ataacagcaa accgcgggga gaggatgatg tgggtgaagg
    24961 atgtgtccag tatataaatt tctagccaag ctggcgatga accagtcctc taaaaaatgg
    25021 gtataatcat agtttattta ctaattaaat taatataaag taattacttt attatatgga
    25081 gaatttatga aaatgggaaa aattgcagtt actcctaata atgataaagc agccagccac
    25141 tctaaagatg aaaatttagc cacaaataca attaagaaaa acgtaaaacc taaatatggc
    25201 gatgcggcat ttttagagta cactcgacta atagttaacc acccgaatta ttttggaatg
    25261 ccagatccct ttggggaaaa aggtgagatt caatgggaag ctccatcaaa tagggcatcg
    25321 gggaaattta aacacactca tcaacggcgc tatgaatggt ggaaaaataa agccagaagt
    25381 attgggatag accctgacac tgaaaaagca tggattagta aaacagctaa actaattcat
    25441 ccacttggag ttaaaccatg caagaaatgc ggtaaagaaa tggaattatc ttactcctac
    25501 ccaaatgagc atttcttttc tcgggttagg aaacttaatt atatagatga gacttttgag
    25561 ctatctcaaa atgaacacat agttgatttg ttgactcgtt tagatgatag atttggtgaa
    25621 agaatatatt tagatttacc acatttattt tctacaaaat ccatcacgat tccagatatt
    25681 tcaagcaatc tcgaagcatg gattgagtat ctaaaagaac aatacatacc tcaagaatca
    25741 cgtatgctta gccctggagc catggcaaat cctccagatc gttttgatgg atttcattca
    25801 tttaaccgct gttgtcgctc tattgctgat aaaggaagga ccaaagaaaa tcttaaatct
    25861 tatgttactg acagaagagt tttcgaatat tgggtggatg gtgattgggt agctgcagac
    25921 aggctaatgg gccaagttag aacaaataat atatttatta acgaggaatg tttgaatgcc
    25981 ggaaatggtg gtttacatcc aactccttgc caagcagatc acattggccc aatctcacta
    26041 gggttttccc atcgcccaca atttcaacta ctttgcaaat catgtaatag tgccaaaaac
    26101 aatcgtatgt atttaagtga tataatctct ttattagaag ctgagaatga aggtcatacg
    26161 gttatttcat ggttcgcaga agaagtatgg aatcgactaa aacactctgt agatgatagt
    26221 gaaaaagcct taagactaag taaaatacta cgtgataata gacatacata tatgaatctt
    26281 cttaaaaaaa taatggatga aggttattat actttccttg caagtctttt acatcttgag
    26341 gtagccaatt ataacccaat atttgaggga tt
//
LOCUS       DAFGPF010000067        26045 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFGPF010000067 DAFGPF010000000
VERSION     DAFGPF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26045
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.067"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(156..296)
                     /locus_tag="LSX49_003080"
     CDS             complement(156..296)
                     /locus_tag="LSX49_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169459.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILT
                     AI"
     gene            392..1108
                     /gene="arcA"
                     /locus_tag="LSX49_003081"
     CDS             392..1108
                     /gene="arcA"
                     /locus_tag="LSX49_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HBL7169460.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            complement(1168..2520)
                     /gene="creD"
                     /locus_tag="LSX49_003082"
     CDS             complement(1168..2520)
                     /gene="creD"
                     /locus_tag="LSX49_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HBL7169461.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDV
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEDDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELDAPNITLGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDLRKQNLKLNVALNLSGTGDLSVVPGGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHTGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLVLLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTMDDELRIWK
                     "
     gene            complement(2578..4002)
                     /gene="creC"
                     /locus_tag="LSX49_003083"
     CDS             complement(2578..4002)
                     /gene="creC"
                     /locus_tag="LSX49_003083"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HBL7169462.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDAQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPDLGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTAVDVAALF
                     RRVSEARTVQLAEKNITLHVMPTEINVAAEPALLEQALGNLLDNAIDFTPESGRITLS
                     AEVDQEYVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQEGGVLASLRLHRHFT"
     gene            complement(4002..4691)
                     /gene="creB"
                     /locus_tag="LSX49_003084"
     CDS             complement(4002..4691)
                     /gene="creB"
                     /locus_tag="LSX49_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HBL7169463.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFGVEVFERGLPVLDKAR
                     QQVPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSTPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            complement(4704..5177)
                     /gene="creA"
                     /locus_tag="LSX49_003085"
     CDS             complement(4704..5177)
                     /gene="creA"
                     /locus_tag="LSX49_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HBL7169464.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
     gene            5388..6257
                     /gene="robA"
                     /locus_tag="LSX49_003086"
     CDS             5388..6257
                     /gene="robA"
                     /locus_tag="LSX49_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HBL7169465.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            complement(6254..6901)
                     /gene="gpmB"
                     /locus_tag="LSX49_003087"
     CDS             complement(6254..6901)
                     /gene="gpmB"
                     /locus_tag="LSX49_003087"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HBL7169466.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLETRNIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            6953..7480
                     /gene="yjjX"
                     /locus_tag="LSX49_003088"
     CDS             6953..7480
                     /gene="yjjX"
                     /locus_tag="LSX49_003088"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HBL7169467.1"
                     /translation="MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSA
                     TLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRTSVYHQAVIL
                     ALSPFHNAVYQPLQA"
     gene            complement(7559..7885)
                     /gene="trpR"
                     /locus_tag="LSX49_003089"
     CDS             complement(7559..7885)
                     /gene="trpR"
                     /locus_tag="LSX49_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HBL7169468.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLED
                     VLLKSD"
     gene            complement(7975..9912)
                     /gene="sltY"
                     /locus_tag="LSX49_003090"
     CDS             complement(7975..9912)
                     /gene="sltY"
                     /locus_tag="LSX49_003090"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HBL7169469.1"
                     /translation="MEKAKHVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     QIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            10119..11786
                     /gene="ettA"
                     /locus_tag="LSX49_003091"
     CDS             10119..11786
                     /gene="ettA"
                     /locus_tag="LSX49_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HBL7169470.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDSLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            complement(11907..13139)
                     /gene="nadR"
                     /locus_tag="LSX49_003092"
     CDS             complement(11907..13139)
                     /gene="nadR"
                     /locus_tag="LSX49_003092"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418807.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HBL7169471.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRYLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIETVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQR"
     gene            complement(13160..14542)
                     /gene="radA"
                     /locus_tag="LSX49_003093"
     CDS             complement(13160..14542)
                     /gene="radA"
                     /locus_tag="LSX49_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBL7169472.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKTPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            complement(14591..15559)
                     /gene="serB"
                     /locus_tag="LSX49_003094"
     CDS             complement(14591..15559)
                     /gene="serB"
                     /locus_tag="LSX49_003094"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HBL7169473.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGERVAEVTERAMRGELDFTASLRS
                     RVATLKGADANILQQVRENLPLMSGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKTEVTIRHADLMGVFCILSGSLNQK"
     gene            15665..16309
                     /locus_tag="LSX49_003095"
     CDS             15665..16309
                     /locus_tag="LSX49_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HBL7169474.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVDVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            16337..17353
                     /gene="lplA"
                     /locus_tag="LSX49_003096"
     CDS             16337..17353
                     /gene="lplA"
                     /locus_tag="LSX49_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HBL7169475.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHI
                     TRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFQEQEKELRELSAWMA
                     GAVR"
     gene            complement(17354..18685)
                     /gene="yjjJ"
                     /locus_tag="LSX49_003097"
     CDS             complement(17354..18685)
                     /gene="yjjJ"
                     /locus_tag="LSX49_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HipA family toxin
                     YjjJ"
                     /protein_id="HBL7169476.1"
                     /translation="MSELTDLLLQGPRSAPELRQRLAISQATFSRLVARENRVIRFGK
                     ARATRYVLLRPYRGIERIPVWRVDDAGKAHKFADIRLCWPQGSCLVTGADGDEQWFDG
                     LPWYLTDLRPQGFLGRAWGRKLAAQLNLTDDIRLWQEEDVLYALTVFNGEYTGGWLVG
                     EGNYQRWITAQRPAEIPLDQKLTRYEQLASDALAGEIVGSSAGGEQPKFTCYAQTPSG
                     NKHVLVKFTVPQQTAVSQRWGDLLIAESIAAQILRDGGIHAIESTVLVTSNRQVFLEA
                     ERFDCKGNDGRLPIVSLEAVQSEFISSPGSWPEAMRHLCEQQLVTHQSVAQTEVIWAF
                     GRLIANSDMHAGNLSFYLSEPPFALTPVYDMLPMAYAPNSAGMLRDAAIEVKFDLNIS
                     KSAWLTAIPLAQQFWQTVARDPRISEAFRHIAQEMPEKIRQIEEKVTRMGG"
     gene            complement(18852..19571)
                     /gene="deoD"
                     /locus_tag="LSX49_003098"
     CDS             complement(18852..19571)
                     /gene="deoD"
                     /locus_tag="LSX49_003098"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL7169477.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(19628..20851)
                     /gene="deoB"
                     /locus_tag="LSX49_003099"
     CDS             complement(19628..20851)
                     /gene="deoB"
                     /locus_tag="LSX49_003099"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL7169478.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     HGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            complement(20903..22225)
                     /gene="deoA"
                     /locus_tag="LSX49_003100"
     CDS             complement(20903..22225)
                     /gene="deoA"
                     /locus_tag="LSX49_003100"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313368.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HBL7169479.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEHRNPRLFDVT
                     MALCVEMLISGKLAKNDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            complement(22303..23082)
                     /gene="deoC"
                     /locus_tag="LSX49_003101"
     CDS             complement(22303..23082)
                     /gene="deoC"
                     /locus_tag="LSX49_003101"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL7169480.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            23340..24890
                     /locus_tag="LSX49_003102"
     CDS             23340..24890
                     /locus_tag="LSX49_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HBL7169481.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLAHGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDEIDIRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPDITPDDLLLEVAKNVCECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLIDPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            24862..25725
                     /locus_tag="LSX49_003103"
     CDS             24862..25725
                     /locus_tag="LSX49_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HBL7169482.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVPQCPHQALQIVDGKVVWNAVVCEQCDTCLKRCPQHATPMAQSMSVDEV
                     LSHVRKAVLFIEGITVSSGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPGQ
                     VDYLQHIEELAAFIKGLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VSRLIFPALYL"
BASE COUNT         6119 a         7214 c         6657 g         6055 t
ORIGIN      
        1 agttgtatga tgcaactagt tggattatta aaataatgtg acgaaagcta gcatttagat
       61 acgatcattt catcaaactg ttaacgtgct acaattgaac ttgatatatg tcaacgaagc
      121 gtagttttat tgggtgtcct gcccctctta gcctgttata ttgctgttaa aatggttagg
      181 atgacagccg tttttgacac tgtcgggtcc tgagggaaag tacccacgac caagctaatg
      241 atgttgttga cgttgatgga aagtgcatca agaacgcaat tacgtacttt agtcatgtta
      301 cgccgatcat gttaatttgc agcatgcatc aggcaggtca gggacttttg tacttcctgt
      361 ttcgatttag ttggcaattt aggtagcaaa catgcagacc ccgcacattc ttatcgttga
      421 agacgagttg gtaacacgca acacgttgaa aagtattttc gaagcggaag gctatgatgt
      481 tttcgaagcg acagatggcg cggaaatgca tcagatcctc tctgaatatg acatcaacct
      541 ggtgatcatg gatatcaatc tgccgggtaa gaacggtctt ctgttagcgc gtgaactgcg
      601 cgagcaggcg aatgttgcgt tgatgttcct gactggccgt gacaacgaag tcgataaaat
      661 tctcggcctc gaaatcggtg cagatgacta catcaccaaa ccgttcaacc cgcgtgaact
      721 gactattcgt gcacgcaacc tgctgtcccg taccatgaat ctgggtactg tcagcgaaga
      781 acgtcgtagc gttgaaagct acaagttcaa tggttgggaa ctggacatca acagccgttc
      841 gttgatcggc cctgatggcg agcagtacaa gctgccgcgc agcgagttcc gcgccatgct
      901 tcacttctgt gaaaacccag gtaaaattca gtcccgtgct gaactgctga agaaaatgac
      961 cggccgtgag ctgaaaccgc acgaccgtac tgtagacgtg acgatccgcc gtattcgtaa
     1021 acatttcgaa tctacgccgg atacgccgga aatcatcgcc accattcacg gtgaaggtta
     1081 tcgcttctgc ggtgatctgg aagattaatc ggctttacca ccgtcaaaaa aaacggcgct
     1141 ttttagcgcc gtttttattt ttcaacatta tttccagata cgtaactcat cgtccatggt
     1201 aacttcttta ctggctttca ttttcggcag tgaaaacgca taccagtcga tattacgggt
     1261 cacaaacatc atgccggcca gcgccaccac cagcacactg gttcccaaca acagcgcgct
     1321 atcggcagag ttgagcagtc cccacatcac accatccagc aacaacagca cgagggtaaa
     1381 caacatgcta ttacgccagc ctttcaatac cgcctgcaaa taaataccgt tcattaacgc
     1441 cccaatcaga ctggcgatta tccatgccac agtaaaaccg gtatgttcag aaagcgccag
     1501 caagagcaaa taaaacatca ccaatgaaag ccccaccagc aaatattgca ttgggtgtaa
     1561 acgttgcgcg gtgagcgttt caaaaacaaa gaatgccata aaagtcagcg caatcagcag
     1621 aatggcgtac ttagtcgccc ggtccgttaa ttggtattga tcggctggcg tcgtcactgc
     1681 gacgctaaac gcggggaagt tttcccagcc ggtatcattg cctgaagcaa aacgctcacc
     1741 gagattatta gcaaaccagc tactttgcca ttgcgcttga aaacctgact cgctaacttc
     1801 ccgtttggct ggtagaaaat cacctaaaaa actgggatgc ggccagttgc tggttaaggt
     1861 catttcgcta ttacgcccgc caggcaccac agaaagatcg ccggtaccgc ttaaattcag
     1921 cgccacattc agcttcaggt tctgcttgcg caagtcccct tcgggtaaag ggatatgcac
     1981 gccctgcccg ccttgctcta acccggtgcc gggttcaatg gtcagcgccg taccgttaac
     2041 ttcaggcgct ttcaccacac caataccacg cgcatccccg acgctaatca caataaatgg
     2101 cttgcctaag gtgatatttg gcgcgtcgag ttcgctaaga cgcgaaacat cgaaatcggc
     2161 ttttagcgtt aaatcactgt gccagacctg accggtatag atgcctatct tgcgttcttc
     2221 cacattctga ttgccatcaa ccatcaatga ctcaggtaac caaaaatgaa taaaacttcg
     2281 tttccgctcc acggttttat cgtcttcctg caccgtataa agctcggtca caggaatagc
     2341 gatgagcggc ccaacgagtt tttgcggccc gctggtactt tggcgaatca catcttccac
     2401 atcgctacgg taatcggcac gttcgacaat cacctgccga atcagcatta tcggaatcaa
     2461 caacagcaat actgcaccaa acaaggtggt cattttccag aacagggggg atttcaacat
     2521 agtcttctcc tttgcaatga cagcaggata cgaaggctat gtgggaagaa tttgaagcta
     2581 tgtgaagtga cggtgaagtc gaagcgaggc cagcacgcca ccttcctgca cgttgcgcag
     2641 cgtgacttcg ccgttaaaca aacgggcgac ctcactgaca aacgccaacc ccagaccgct
     2701 gcttttttgc ccatttgcac gcggcaaaga gtaaaagcgt tcaaaaatac gtgacagcgc
     2761 gtagtcagga atcccactac cggtatccag caccttaagg gtgacgtatt cctgatccac
     2821 ttcggcgctt agcgttatgc gaccgctctc gggagtaaaa tcgatggcgt tatccagtaa
     2881 attccccagc gcctgctcca gtaacgccgg ttcagcagca acgttaatct cagtaggcat
     2941 aacatgcaaa gtgatgtttt tttctgccaa ctgcacggtg cgcgcttcgc tgacgcggcg
     3001 aaataatgcc gccacatcaa cagcagtcag aacgacttcc tgacgattct ccagtcttgc
     3061 ctggcgtagt aacgtttcca ccagtgcctg cattcgcgca ttttgcgtca gaatgttgtc
     3121 ggtaaaacga gccaccactt ccggcggcgg accttcgcgt aaaatttccg ccgcgccacg
     3181 aatcgccgcc agtgggcttt ttagctcatg agttaacgca taaacatact gctcaatata
     3241 gtttttccct tccagcttca cgcgcatact ttccagcgcc tgcgcgagtt tacgcagctc
     3301 gctactaccg agatcgggga gaggaacggg cttattgtca gtgacggaat cagcatagcg
     3361 agtgagccgg gcaatagagc ggttgatcca ccaaaccatg cctgcgccaa tcaccagtgc
     3421 aatccccaac aaaatggcgc tggcccataa aattcgccgc tcgctacgct taatgaccgg
     3481 ggccatcgcc gcgttcggtt tgcctacgct caaaacgcca ataagccgcg agccgtccat
     3541 aatcggcgcg gcaacataca tcacagaact ttcgggatcg gcaggatttt gcaacgtgct
     3601 gcgcgcacca tactgaccac gcaacgttag ccagacgtca ttccagcgcg aataatcctg
     3661 tccaacggct ttatttgccg aatcaaacaa tactttgccc tgcgcatcgg tcatatagac
     3721 atgatattcg ttgcgcactt tgttaatgcc accgatattg gcgcgaaacg ggcgatgttg
     3781 tagctgatta aacgcctgcg ccagttgccc atgcgttggg tccccagaga gcaaatcggg
     3841 acgcgccagc tccgccagca acgttgcggt gtcgattaac gtcccctcgg ttgctcttcg
     3901 cacgcccggt ttaacttctt tgacaaaaat agccagtacg aaccaggccg ccaccgccac
     3961 cagtaaaaaa tagcccagca acaaccgcat gccgatacgc attacaggcc cctcaggcta
     4021 tatcccatgc cgcgatgagt attaatcggt gaaagatcgg ggttgatggc gcgcagcttg
     4081 gcacgcagcg ttttaatgtg ggtatcgacg gtgcgatcgt aggtgtcctg cgcatcttcc
     4141 cacacgctat ccattagttg ctggcgggac cagacgcggc ccggcgactt gagtaacgtc
     4201 ttcagcaata aaaactcata ccgcgtcagc gttaatggcg tgtcaaacca gctgatctgc
     4261 gccgcaggtt cattcaattc aaaatgacca atacggataa cgggagacgg cgtcgagaac
     4321 ttcttcaccc gacgcagtaa ggtgcgcact ctggcgcaca cttcgcgagg tgaaaacggt
     4381 ttagccacgt agtcgtcagc gccaatttcc agcccaagca ggcgatcgac ctcttcactt
     4441 cgggccgtca ggaacagtac aggtaacgcc ggatggagcg ccagtaactg gcggcacaat
     4501 tcaaagccgc tgatatcagg caaaccaaca tcgagaatca tgacatcggg aacctgctgg
     4561 cgagctttat ccagcactgg caagcctcgc tcaaagacct cgacgccaaa accttcctgt
     4621 tgcaacatgt agaccagcgt atcggctatc ccttgctcgt cttctactaa ccagaccgtt
     4681 tcccgttgca taaatcgcct ctgttattgc cgccacggca tgacaggaac cgcgctaatc
     4741 gcgtttttcg gcgaaccttc tacaactttg tcggagtaag ccagataagc gagcgcgttg
     4801 cgtttagcgt cataaaagcg cacgacctgt aacgacttaa agaccaggga cgtgcgtttt
     4861 ttgaatacta cctcgccctg agctttgccg tttttaatac gatccgacag ttcaatcggc
     4921 ccgacttgtt gacaagaaat ggccgcatcg gaggtatctt ctgccaggcc caatccccct
     4981 ttaataccac cggttttcgc ccggctcaca taacaggtga catttttcac atcgggatcg
     5041 tcaaaggctt caacaacaat tttgtgatcc gggccgatca ttttaaatac ggtgtcgacc
     5101 gaaccaatct cttctgcatg agccaatggc cccagcatta tcaggcttaa agaaaggatt
     5161 aaatgcttgt atttcatatt gttaccattt ttatctatta cacgagcaat tagttcgtca
     5221 cggtaaataa catattgatt aagaacaaaa tctcaatact tttatttccg tcaagcccta
     5281 aaacatactc gactaagaaa aaaacactga atgctaaaac agcaaaaaat gctattatcc
     5341 aattacctga tgtcaggtgc tcgttgttga aaggatgagg atattttatg gatcaggccg
     5401 gcattattcg cgacctttta atctggctgg aaggtcatct ggatcagccc ctgtcgctcg
     5461 acaatgtagc ggcgaaagca ggttattcca agtggcactt acagagaatg tttaaagatg
     5521 tcactggcca tgctattggc gcgtatattc gtgctcgtcg tttgtcgaaa tcggcggtcg
     5581 cactacgcct gactgcgcgt ccgattctgg acatcgcgct gcaataccgc ttcgactctc
     5641 aacagacatt tacccgcgca ttcaagaagc agtttgccca gactcctgca ctttaccgcc
     5701 gttctcctga atggagcgcc tttggtattc gcccgccgct gcgtctgggt gaattcacta
     5761 tgccagagca caaatttgtc accctggaag atacgccgct gattggtgtt acccagagct
     5821 actcctgttc gctggagcaa atctctgatt tccgccatga aatgcgctac cagttctggc
     5881 acgattttct cggcaacgcg ccgaccattc cgccggtgct ctacggcctg aatgaaacgc
     5941 gtccgagtca ggataaagac gatgaacaag aggtattcta taccaccgcg ttagcccagg
     6001 atcaggcaga tggctatgta ctgacggggc atccggtgat gctgcagggc ggcgaatatg
     6061 tgatgtttac ctatgaaggt ctgggaaccg gcgtgcagga gtttatcctg acggtatatg
     6121 gaacatgcat gccaatgctc aacctgacgc gccgtaaagg tcaggatatt gagcgatact
     6181 acccggcaga agatgccaaa gcgggagatc gcccaattaa tctgcgctgt gaactgctga
     6241 ttccgatccg tcgttaacgc tgcagctcat ctaatgcagg ggcgtccaga tgcgagatgt
     6301 cccctgcggt ttcaaccacc cagccagacg ccagccacag gctttcctga taatccacgc
     6361 gcgaaataga acagttacgc agacgtaagc ggcgctctgc ccatgctggt aatccgagaa
     6421 tcgtactcac caggcatccc agtgcaatac catggctcac cagtagcggt cggcttccct
     6481 gcggtaagtc ccggcaagat tccagtgccg cattaacgcg atcgctgagc tcctgcattg
     6541 actcgccttc aggaatacgc ccgtcaacgg tgccattgac cagttgccga cgccagttct
     6601 cttcttcttc ggtgagtgaa tcgatatttc ttgtttccag tacacccata tttaattcac
     6661 gcaggcgaga atcaaatatg atgtcacagc cgcaggcctg ggcgatgatt tccgccgtgc
     6721 gccgggtgcg tcctaaatcg ctactgatga tatgcgtaat gccaagctct ttggcacggg
     6781 ttgccacctg catcgcctgt tgctcacctt tggcggtcag cgggctgtca gactggccct
     6841 gaatacgtcg ctcggcgttc cactgcgttt caccgtggcg gactaggtat acctgtaaca
     6901 tgcttttttt ccgtatactg ctgtaacgtt aattttctga gtaatgctga ttatgcacca
     6961 agttgtctgt gcgaccacca atcccgctaa aattcaggcc attctgcagg catttcacga
     7021 gatcttcggc gaaggatcct gccatattgc atccgttgcc gtcgagagcg gtgtaccgga
     7081 acagcccttt ggcagtgagg aaacgcgcgc tggcgcacga aatagggtag ccaatgcccg
     7141 ccgtttactt cctgaggctg atttttgggt ggcgattgaa gctggcatcg atggtgacag
     7201 cactttcagt tgggtggtga ttgaaaacgc cagccagcgc ggcgaggcgc gttcggctac
     7261 tttgccgttg cctgcggtga ttctggaaaa agtgcgtgaa ggtgaggcgc ttggtcccgt
     7321 gatgtcgcgt tataccggta ttgatgagat tggtcgtaag gaaggggcga tcggcgtgtt
     7381 taccgccggg aaactcactc gcaccagcgt ctatcaccag gcggtgatcc tggcgctgag
     7441 tccgtttcat aatgccgtgt atcagccatt gcaggcctga ttaggcgttc acgccgcatc
     7501 cggcattcgg tgcacgatgc ctgatgcgac gctgacgcat cttatcaggc ctacaaaatc
     7561 aatcgctttt cagcaacacg tcttccagcc actggcgcag ctcgacgggc gcggctttca
     7621 gactattaga tccacgcgta atcgtcgcga tgcccgcgcc gagttcattt tttaactcac
     7681 gctggctcat ttcgccgcgc aacagctctt cgacaatacg cacgcgagtc cccaacgctt
     7741 cgcgctcatc tggcgtcagc atcaggttta acaacggtaa atggagatcg ttttggtagg
     7801 cattcttaag caggtcgaca aaacgtaacc actcctggtg acgctgttct gccatcgctg
     7861 ctgaataggg tgattgttgg gccatagtat gtcgccattg ttagcggggg aagcaaaatg
     7921 cctcccccgg ttgtactcgc taaagagtac gatagcatat cataaacgtg tggatcagta
     7981 acgacgtccc cattccgtgg cgctcatcaa cgtcggttta tcccccatga aatagcggta
     8041 gtaagcgtca taagccagca cgtttttcac ataaccgcgc gtctcggaga atggaatact
     8101 ctcgacaaat gccactgcgt cgatacgccc tgcgctgttg ccaagccagg tccgcacccg
     8161 ccctggtccg gcgttataag ctgctgagga gaaaatacgg ttattgccaa actgctgata
     8221 aacatattgc aggtaactgg tgccaatgtt gatgttcgtt tccggatcca gcaattgccc
     8281 agggctgcta taaccgggaa tagagaacat cttcaccgta tgggtcgcgg taccaggcat
     8341 aatctgcatc aggccgctgg cccctaccgg tgatttcact ttcggattcc aggcactctc
     8401 ctgacgagca atcgccatcg catagctttg cgggatctcc ttaccactgg tgtagcgttt
     8461 gaaaagatcg ttgtaagcca gcgggaatcg ctcttccaga tgatcccaca gcttcccggc
     8521 gatcgttgcc tgaacgctaa gatcccacca ttggttattg aaagcatacc gagccagttg
     8581 agcctgctct gtttttgact tgctcttcac cagattggcc cactcgctac gcgcggtgtt
     8641 atcgagattc cagtacatca actcgcgcac gcgcgccatc tccggcccct gagtcagggc
     8701 gctgtcaaca ttctgcggcg ctttatcaat cttcagctca tactcttcgc cgatgcgttg
     8761 tgcagcaacc atcgggtaga aaccacgctg ttgcatgagt tgatgcaaaa tctcttttgc
     8821 ttcagcttca cgtccgcgtt ccagcagtaa atccgcctgc cagtaacgcc attcatcttt
     8881 ctctttcgct tccataggca gacgcgccag ccaggtattc aggccgcgac gatcgccggt
     8941 gccaagcgcc attcgcacac ggcgttcaat aagcgaagta gattgcgagc gcataatcgc
     9001 gtcatcgcgc catttcgcct gctcgtcggt gacatcgttg cccatcaaac gccaggcgac
     9061 aatatcgcgc agctcctgaa tctgatcttc attaagctgc tgtgcctgag caagcgacgg
     9121 gatcatcagc cgtgcatttt cagcatcctg ccgcgccaca ctggcaaacg ccaccgccgc
     9181 catttgacgg gtaaaatcgg tcgcgccggt tgtacgcgcg aaggtcagta ccgtattagg
     9241 gttgttcgcc agtgaaatga ttgccgaagc gatagtctgg taatcggcag gcatctgccc
     9301 tgccagcact gttaccaggc cggtgttacc cgctttcatc gccagacgga tacgctctaa
     9361 atacgccagc ggatcttgtt tacctgacgc acgccagacg ctaaataact tgtcacaggc
     9421 gttaggctgg ctcttgccgg ttagccacag ctctttcgcc ccttgccagg cttcttcact
     9481 ctgcccggtg ttccatttcg catagtagta attacattgc gcttcggtag ttccgggctt
     9541 ttccgggcta aaggctaaca agccacgcca gtcttcacgc cgcgccagtt cattgacgaa
     9601 acgagattgc agcgtgcgag cgggaggaag cgtggggtta gcgcgaacaa agttagtgac
     9661 cgtcaccgcc ggttgattca tcaggtcatc agtgatctgg cggtattcca ggtagggata
     9721 aagtgggtaa tctttcagtc caggcatcat ttgttcgacc acatccattt gtcgattatc
     9781 ccaggcctgc ttaatttgcg cgtaacggct acgctgctca tccagtgagt cggctcgcgc
     9841 cacgctgctg accgtcagca gacagacacc ggcagccaac agccgccagg taacgtgttt
     9901 ggctttttcc acaagcgcat cctctaagtg taaatacatc aatgcagcgt catgccgcgt
     9961 aatagattta tgctaaccag tcattgccgt ttacgccacg ttacggacac ttttttactt
    10021 ttacggggtg atcgactggc tgggattaga cagggaaaca ggctacactt cgcctttgaa
    10081 aactcatcat cacgataaac atagaggcga agtccaacgt ggctcaattc gtttatacca
    10141 tgcatcgtgt cggcaaagtt gttccgccga aacgtcatat tttgaaaaac atctctctga
    10201 gtttcttccc tggggcaaaa attggtgtcc tgggtctgaa cggcgcgggt aagtccaccc
    10261 tgctgcgcat tatggcgggc attgataaag acatcgaagg tgaagcgcgt ccgcagccag
    10321 acatcaagat tggttatctg ccgcaggaac cgcagctgaa cccggaacac accgttcgtg
    10381 agtccattga agaagcggtt tctgaagtgg ttaacgccct gaaacgcctg gatgaagtgt
    10441 atgcgctgta tgccgatccg gatgccgatt ttgacaagct ggccgctgaa caaggccgtc
    10501 tggaagagat cattcaggct cacgacggtc acaacctgaa cgttcagctg gagcgtgcgg
    10561 cggatgcgct gcgtctgccg gactgggatg cgaaaatcgc taacctttcc ggtggtgagc
    10621 gtcgtcgcgt ggcgttgtgc cgcctgctgc tggaaaaacc agacatgctg ctgctcgacg
    10681 aaccgaccaa ccacctggat gcggaatccg tagcgtggct ggagcgcttc ctgcacgact
    10741 tcgaaggcac cgtggtggcg attacccacg accgttactt cctcgataac gttgcgggct
    10801 ggatcctcga acttgaccgc ggtgaaggta ttccgtggga aggtaactac tcctcctggc
    10861 tggagcagaa agatcagcgt ctggcgcagg aagcttcaca agaagcggcg cgtcgtaagt
    10921 cgatcgagaa agagctggag tgggtacgtc agggaactaa aggccgtcag tcaaaaggta
    10981 aagcacgtct ggcgcgcttt gaagaactca acagcaccga atatcagaaa cgtaacgaaa
    11041 ccaacgaact gtttattcca cctggaccgc gtctgggcga taaagtgctg gaagtcagca
    11101 acctgcgtaa atcctatggt gatcgtctgc tgattgactc cctgagcttc tcgatcccga
    11161 aaggagcgat cgtcgggatc atcggtccga acggtgcggg taaatcgacg ctgttccgta
    11221 tgatctctgg tcaggaacag ccggacagcg gcaccatcac tttgggtgaa acagtgaaac
    11281 tggcgtcggt tgatcagttc cgtgactcaa tggataacag caaaaccgtt tgggaagaag
    11341 tttccggcgg gctggatatc atgaagatcg gcaacaccga gatgccgagc cgcgcctacg
    11401 ttggccgctt taactttaaa ggggttgatc agggtaaacg cgttggcgaa ctctccggcg
    11461 gtgagcgcgg tcgtctgcat ctggcgaagc tgctgcaggt tggcggcaac atgctgctgc
    11521 tcgacgaacc aaccaacgac ctggatatcg aaaccctgcg cgcgctggaa aacgccctgc
    11581 tggagttccc gggctgcgcg atggttatct cgcacgaccg ttggttcctc gaccgtatcg
    11641 ccacgcacat tctggattac caggatgaag gtaaagttga gttcttcgaa ggtaacttta
    11701 ccgagtacga agagtacaag aaacgcacgc tgggcgcaga cgcgctggag ccgaagcgta
    11761 tcaagtacaa gcgtattgcg aagtaatgcg taaaatgccg gatgcggcgt aaacgcctta
    11821 tccggcctac aaaccaagca atttcaatac gttgtgaatc tccaggcctg ataagacgcg
    11881 gtaagcgtcg catcaggcat tggttcttac ctctgctccc ccatcatctc ccgcaccagc
    11941 tccacgcagc gcagaaaacg gctgtcgtaa tcgtcctctt caacccgcac gaattcgata
    12001 ttgttctctt ccagcatctc caccagcaag ttctggaact ctttgcgatc caccgaactg
    12061 ccgaggctgc gtaaaccatc cgccacccac ggcgtgttgt tctccagcag gatcaccaga
    12121 tcgaaacggt attcatcaat caacgcctgc acaaacggat gctcacgccc ttcgtacttt
    12181 ttgcagaacg cctgggtagt gacaaaatcg gtgtcgataa acgccacttt attggcatat
    12241 ttcactgcaa aatcaatata ttgcgcatgt cccagcgcga ttttatcgta gtcggaatac
    12301 tgcaacgcga tctcatcgcc accgaggtgc gaaaagacat aatcacgacc atattcccac
    12361 gcactggtag tgttgaagat attggcaagt ttgtttacca gggtggattt accgctcgat
    12421 tcaccaccga ggatcgccac ggtacgcaca aagaatggct tcacttccgt aggaatatat
    12481 tcccagtagc ggaacgggtt ttcgcggatc tgcgcaccgc tgatactcat aaaggtacgc
    12541 ttcggatcga ccagcaccgt ctcgatcccc agatgttcca tatactgtgg cgcatcggct
    12601 tcttccgagg tgtagatcag gtccggctga atcccttttt cagccataaa ctttttgatg
    12661 ccgttgctcc atacatccca gccgtgtgga tatggctcca tgccctcttc attgaaagca
    12721 tgaatacgga tatttttctg atatttaaag gtttgcaata gccagcgcag acgatccggc
    12781 accgtgggct gctgcgacat ggcgctgtct tcgaacaatg cgcggtcgcg ggtatcgtca
    12841 aaacccataa tgatatgcag ctcgtcaacc tggctacagg cgcgctggat aaggtagata
    12901 tgtccggtat gcagcgggta aaacttaccg aatacgacac cgatcgtttt cttctgccgg
    12961 ggaaattcaa gtcccaaata acggtgcaat gcctccagct tttgtgcgct ggggctttta
    13021 attttggcat tcagtaactg gcttaaatac cctttggtca taccgctggc atcagctacc
    13081 tgctgtagcg tgcagccctg ttgcttgatg gcagttttca ggtaatcaaa tgacgacata
    13141 tctccctccg tatctctcat tataagtcgt cgaacacgct aagcgcgtcg gagagttttt
    13201 taacgccaaa aatctgcatc ccttccggcg tttttttcgg cacgttagcc gccggaacaa
    13261 tcgcccggcg aaaaccgtgt ttcgccgctt ctgagattcg ttcctggccg ctgggcaccg
    13321 ggcggatctc ccctgccagc ccgacttcac caaacaccac cagatcctgc ggtagcggtc
    13381 tgtcacgcag gctggaaacc atcgccagca gtaacgctaa atcggcactg gtttccgtca
    13441 ccttcacgcc accgaccacg ttaacaaaca catcctgatc ggccatttgt agaccaccgt
    13501 gacggtgaag caccgccagc aggattgcca gacggttttg ctccagcccg actgccacgc
    13561 ggcgtggatt cgccatcatc gagtgatcga cgagcgcctg aatctccacc agcagcggac
    13621 gcgttccttc ccacactacc atcactgagc taccggaggt cacttcatcg ccgcgactta
    13681 agaaaattgc cgaagggttg ctgacttcac gcagcccctg ctcggtcatt gcaaagacac
    13741 ccagctcatt caccgcgccg aagcggtttt tatggctgcg taaggtgcga aaacgggagt
    13801 cggcatcgcc atccaaaagc accgaacagt cgatacagtg ttccagcact ttagggccag
    13861 ccagcgagcc atctttggtt acgtgcccaa ccatgacaat cgccacaccg cgcgttttgg
    13921 cgaagcgcgt cagataagcc gccgtttcac gcacctgtgc cacgctgcca ggcgatgatt
    13981 gtacatccgc catatgcatc acctggatgg agtcaattac catcagcttc ggttgctctt
    14041 cttcggcaat caggcagatc tgctcgatgc tggtttccga cagcatatta agattgtcag
    14101 tcggcaggcc aaggcgatga gcgcgcattg ccacctgttg cagcgactct tcgccggtga
    14161 catacagcgt tttcatctgc tgcgccagtt tgcacagcgt ttgcagcaac agcgtggatt
    14221 tccccgcacc agggttaccg ccaatcagaa tggcgcttcc cggcaccacg ccgccgccta
    14281 atacgcggtc gaactcttta aatccggtgg aaaaacgcgg cagctcttca aggctgatgt
    14341 cggaaagttt ctggactttt gccactccgg cgctaccggc atagccactg agacgctcgt
    14401 tacgcgccac cgttggcgac gctgcaagac gcacctcggt gatggtgttc caggcatgac
    14461 aggcactgca ctgcccctgc cagcgcggat aatcggcccc gcattcatta caaacaaagg
    14521 cgcgttttgg agcttttgcc acgatgtacc tcgttaatgc tgtgccgccc gcaggatgac
    14581 gggcggacaa ttacttctga ttcaggctgc cagagaggat gcagaatacc cccatcaggt
    14641 cagcgtgacg gatggtgact tccgtctttt cattcacttt tggcttggca tggtaggcaa
    14701 tccccagccc tgccgctttg atcatcggca ggtcattggc tccatcgcca atcgccacgg
    14761 tctgcgccag cgggatttca tactcctgcg cgaggcgggt cagggttttc gctttatatt
    14821 gcgcgtcaac gatgtcgccg atcacattgc cggtaaattt accgtccatg atctccagtt
    14881 cattggctac cacggctgtc aggcgcagct tgtcgcgcag gtattcagca aagaaagtaa
    14941 agccgccgga ggcaatcgcc actttccagc ccagcgtttc cagcttgagt accagctgcg
    15001 ttaagcctga catcagcggc agattttcac gcacctgttg cagaatattg gcgtcagcgc
    15061 ctttcagcgt cgccacgcgg ctgcgcaggc tggcggtaaa atcgagttcg ccgcgcatcg
    15121 cccgttcggt tacctccgcc accctctcgc ccgttccggc cagtttggca atttcatcaa
    15181 tacattcaat ctggatggcg gtggaatcca tgtccatcac cagcaaaccc ggcgtgcgca
    15241 ggtgtgggat tttccccagc ggtgcgacat ccagttgcgc ttcatgggcc aggcgcgtag
    15301 cccgcgcagt gagtgaacct gccagacgaa tcacctgata atcttccacg caccaggcgg
    15361 caacaatcac catagccgcg cccagtttgc tctggtattg ggtcagacgt tgtttatcca
    15421 gcccacgacc atacagcagc cagccgctac gacctgcgtg gtaatccagt ggcatcactt
    15481 catcaccact taatgaaaga ggcagaccag gccataaaga gacatcttca ggcaagtcgc
    15541 accaggtaat gttaggcatt aaggctcctg taaaatcgtt cgaagcaggg aaaataacgc
    15601 atgaggctac cttgtatcca ttgcttctgg caacattaag tctcaaattt tcaaagggtg
    15661 gaagatggct cgcacaaaac tgaaattccg gctgcatcgg gcagtgattg tcctgttctg
    15721 tcttgccttg ttagtggcgc tgatgcaggg ggcgtcatgg tttagtcaaa accaccagcg
    15781 acagcgtaat ccgcaactgg aagaactggc ccgcaccctg gcgcggcagg tgacgctaaa
    15841 cgttgcaccg ctgatgcgta ccgactcacc ggatgaaaaa cgcattcagg cgatcctcga
    15901 tcagttaacg gatgaaagcc gcattctcga cgcaggcgta tatgatgaac aaggcgatct
    15961 tatcgcccgt tctggcgaaa gcgtcgacgt gcgcgaccgg ctggcgctcg acggcaaaaa
    16021 agcgggcggc tattttaatc agcagattgt cgaacccatt gcgggtaaaa acggaccgct
    16081 cggctatctg cgcctgacgc tcgacaccca tacgctcgcc accgaagccc aacaggtgga
    16141 taacaccact aacattttac gcctgatgtt gctgctctcg ctggcaatcg gcgtagtgct
    16201 gacccgcacg ctgctacagg gtaaacgcac ccgctggcag caatcgccct tcctgttaac
    16261 cgccagcaaa ccggtgccgg aagaggaaga aagcgagaaa aaagagtgac ccattactac
    16321 aagaaaggaa atcgttatgt ccacattacg cctgctcatc tctgactctt acgacccgtg
    16381 gtttaacctg gcggtagagg agtgtatttt tcgccagatg cccgccacgc agcgcgttct
    16441 gtttctctgg cgcaatgccg acacggtagt gattggtcgt gcgcagaacc cgtggaaaga
    16501 gtgtaatacc cggcggatgg aagaagataa cgtccgcctg gcgcggcgca gtagcggtgg
    16561 cggcgcggtg ttccacgatc tcggcaatac ctgttttacc tttatggctg gcaagccgga
    16621 gtacgataaa actatctcca cgtcgattgt gctcaatgcg ctgaacgcgc ttggcgtcag
    16681 cgccgaagct tccgggcgta acgatctggt ggtgaaaacc gccgaaggcg accgcaaagt
    16741 ctcaggctcg gcctatcgcg aaaccaaaga tcgtggcttc caccacggca ctttgctgct
    16801 caatgccgac cttagccgcc tggcaaacta tctcaatccg gataaaaaga aactggcggc
    16861 gaaaggcatt acctcagtgc gttcccgcgt gaccaatctg accgaattgc taccggggat
    16921 cacccatgag caggtttgcg aggccataac cgaggccttt ttcgcccatt atggcgagcg
    16981 cgtggaagcg gaaatcatct ccccggacaa aacgccagac ttgccaaact tcgccgaaac
    17041 ctttgcccgc cagagtagct gggaatggaa cttcggtcag gctccggcat tctcgcatct
    17101 gctggatgaa cgctttacct ggggcggcgt ggaactgcat ttcgacgttg aaaaaggcca
    17161 tatcacccgc gcccaggtgt ttaccgacag tctcaacccc gcgccgctgg aagccctcgc
    17221 cgggcgactg caaggctgtc tgtaccgcgc ggatatgctg caacaggagt gcgaagcgct
    17281 gctggttgac ttccaggaac aggaaaaaga gctacgggag ttgtcggcat ggatggcagg
    17341 ggcggtgcgg tagttaccca cccatgcggg taactttctc ttcgatttgc cggatttttt
    17401 ccggcatttc ttgcgcaatg tggcgaaacg cctcgctgat acgcggatct ctggcgaccg
    17461 tttgccagaa ctgctgcgcc agcgggatcg ccgttaacca tgcgctttta ctgatgttaa
    17521 gatcaaactt cacctcaatg gcagcatcac gcagcattcc ggcgctgttt ggcgcatagg
    17581 ccatcggcag catgtcgtag acgggtgtca gcgcaaatgg tggttcagat aaataaaatg
    17641 ataaattgcc tgcgtgcata tcgctgttgg cgataagtcg cccaaacgcc cagatcactt
    17701 ctgtttgcgc cacgctctgg tgagtgacaa gttgttgctc acacaaatgc cgcattgcct
    17761 ccggccacga tcccggagaa gagataaact cactttgcac cgcctccagc gacacaatgg
    17821 gcaagcgacc atcgttacct ttgcagtcaa agcgttccgc ttccaggaat acctgcctgt
    17881 tacttgttac aagcaccgtt gactcgatgg cgtggatccc gccgtcacgc aggatttgcg
    17941 cggcaataga ttcagcaatt agcaggtccc cccaacgttg gctgactgcg gtttgctgtg
    18001 gcacggtgaa tttcaccaac acatgtttat tgcctgacgg cgtttgtgca tagcaggtaa
    18061 attttggctg ctcgccgccc gcagaagaac ccacaatttc tccagccaga gcatcgcttg
    18121 ccaactgttc gtaacgggtg agtttttgat ccaaaggaat ttccgcaggg cgttgtgcag
    18181 taatccatcg ctgataattc ccctccccga ccaaccaacc gccagtatat tcaccgttaa
    18241 atacggtcag ggcgtagagc acatcttctt cctgccagag acgtatatca tcagtcagat
    18301 tcagttgcgc ggctaacttt ctgccccacg cgcgccctaa aaagccctgc ggtcggagat
    18361 cggtcaaata ccagggcaaa ccatcaaacc actgttcgtc gccatctgcg cctgttacca
    18421 gacaacttcc ctgtggccag cacaaccgga tgtcggcgaa tttatgcgcc tttccggcat
    18481 cgtccacccg ccagacggga atacgctcaa ttccgcgata aggacgcagc agtacatatc
    18541 gcgttgcccg tgctttacca aagcgaatca cccgattttc tctggcaaca aggcgtgaga
    18601 acgtcgcctg actgattgcc agacgctggc gcaattccgg ggcagaacgc ggcccttgca
    18661 gtaaaagatc ggtcagttcg ctcattaatg aatagattcg tgaatagata cttgaataga
    18721 tttattaaca tatttcactg aaaagtatag cgaaaatatt caagctggag agataaatga
    18781 ataaatacta aaaagccgga gcagtctccc actccggctt cacacgacaa tcgcctttca
    18841 gcaaaacaca attactcttt atcgcccagc agaacggatt ccagcgcgat tttgatcatg
    18901 tcgttgaagg tggtctgacg ctcagcggca gtggtctgct cgtgagtgcg gatgtggtca
    18961 gacacggtgc agatggtcag ggctttcgcg ccaaattctg cagcgacgcc gtagataccc
    19021 gccgcttcca tttccacgcc gaggatgccg tatttttcca tcacgtcgaa catttcgccg
    19081 tccggagagt agaacaggtc agcggagaac aggttaccaa cgcgagcatc aacgcccagt
    19141 gcttttgccg cgtctaccgc gttacgcacc atgtcgaagt cagcgatagc ggcaaagtca
    19201 tggtctttaa aacggatgcg gttaactttg gaatcggtgc aggcacccat accgataacg
    19261 acgtcgcgca gttttacgtg cggcagaaca gcgccacagg aacccacgcg gataattttc
    19321 ttcacgccga aatcagtgat cagttctttg gtgtagatgg agcaggacgg gatacccata
    19381 ccgtggccca ttacggaaat tttgcggcct ttgtaagtac cagtgaagcc cagcataccg
    19441 cgaacgttgt tcacttcacg ggcatcttca aggaaagttt cagcaatata cttcgcacgc
    19501 agcgggtcgc ctggcatcaa aactacgtca gcaaaatcgc ccatttctgc attaatgtgt
    19561 ggagtagcca tcgttttatc ctttttgtga catattaaag gcggagtcac tgctccgccc
    19621 aaatccatca gaacatggct ttgccatatt ccatatcaga agtaccaaaa tattttgcca
    19681 gagtctggcc gatatccgcg aaggtttcac gatgacccag cgaacctggt ttcactttcg
    19741 ggccgtaaac cagtaccgga atgtgttcac gcgtgtggtc agtaccggtc caggtcgggt
    19801 cacaaccgtg gtcagcagtg agaatcagaa tatcgtcatc gcgcagcaaa gacatcagct
    19861 ccggcagacg gcggtcgaac agttccagac ccgcagcata accggcgacg tcgcggcggt
    19921 ggccccagga agagtcgaag tcaacgaagt tggtgaagac gatggtgtta tcacccgctt
    19981 ctttcatctc tttgatggtg gcgtcaaaca gcgcgtccag cccggtcgct ttcacttttt
    20041 tggtgatacc gcagttggca tagatgtctg caattttacc gaccgaaacc acctggccgt
    20101 gtttttcatc aaccagtttc tgcagcacgg tcggtgctgg cggctcaaca gccaggtcgt
    20161 gacggttacc agtacgctgg aagttaccgg ctttgtcgcc gataaacgga cgagcgataa
    20221 cacgaccgat gttgtagccg ccgttggtca gctcttcacg ggcgatttcg cacagctcgt
    20281 agagtttatc caggccaaag gtttcttcat ggcaggcaat ctggaacacg gagtcagcgg
    20341 aggtatagaa aatcggcttg ccggttttca tatgctcttc gcccagttga tccagaatga
    20401 ccgtaccgga agagtggcag ttaccgaggt aacccggcag attagcgcgt tcgaccagtt
    20461 tatccagcaa ctcttgcggg aagctgtttt cgtgatcgga gaagtatccc cactcaaaca
    20521 gaaccggcac accagcaatt tcccagtgac cagacggggt gtctttaccg gatgacattt
    20581 cgtgcgccca tgcgtacgcg ccgataactt cagcgttgcc atccattccc gccggaatga
    20641 aaccggtaga accttcgtgt gctttcgcca gcccaagacg ggtcagattt ggcagattga
    20701 gcgggccttt acgaccgtgg tcagcttcgc ctttggcaca agcttctgcg atatgaccca
    20761 gggtgtcagc cccgacgtca ccaaagcgtt ctgcatcttc tgtagcgccg atgccgaatg
    20821 agtccagcac cataataaat gcacgtttca tatgttctcc gtactcagtg cttcaaattt
    20881 aaatgatcgg atcagtatac cgttattcgc tgatgcggcg atagacagtt ggtgtgcttt
    20941 ccggtgcttt atcggcaagt ttaattgccg ctttcaccgc tttcgccgct tcctgccagc
    21001 tgttttcgtc tttcgcgtgg ataactgcca gcggacgctg accgtctacc tggtcgccca
    21061 gacgcgccat atcagtaaag ccgacgctgt aatcgatggt gtcagatgcc tgacggcgtc
    21121 cgccgcccat tgcaaccact gccatcccca gtgcgcgggt atccatttca ctgacaaacc
    21181 cttcggtatc agcatagact gctttcgtca gcatcgctgt cggcagatac ttcgcgtagt
    21241 tctcaacgaa gtcggtcggg cctttttgtg ccgcgaccat acgaccaaag acttctgccg
    21301 ctttaccgtt gtccagcacc gcctgcaatt tcgcgcgcgc ttcggcgtca tttttcgcca
    21361 gtttgccgga gatcagcatc tccacgcaca gtgccatcgt gacatcaaac agacgcgggt
    21421 tacgatgttc acccgtcagg aactgcaccg cttcacgaac ttcaaccgcg ttacctgcac
    21481 tggaggccag tacctgattc atatcggtga gcagcgcggt ggtgcgcacg ccagcgccgt
    21541 tagccacgcc aacaatcgct tcggcaaggg cttcagagag ttcgtaggtc ggcataaacg
    21601 cgccgctacc cactttcacg tccatcacca gcgcgtccag accttccgcc agtttcttcg
    21661 ccagaataga ggcggtgatc agcgggattg aatccacggt tgcggtaata tcgcgggtcg
    21721 cgtagaaacg tttatccgcc ggagccagtg agctggtctg gccgataatc gccacgccga
    21781 cgtctttaat aatttcgcgg aaacggttgt catccgggaa aatgtcgaag ccagggatgg
    21841 attccagttt gtcgagcgta ccgccagtat gaccgaggcc gcgaccggag atcatcggaa
    21901 tatagccgcc acaggcagcg accattggcc ccaacatcag cgaagtcaca tcgccgacac
    21961 cgccggtcga gtgtttatca acaatcgggc cattcagatg caggcttttc cagtcgagaa
    22021 cggttcctga atctcgcatc gccatggtca gcgagacacg ctcaggcatt gtcatatcgt
    22081 ggaagaaaat ggtcatcgcg agggcggcaa tctgcccttc ggagatagtg ttgtcgcgaa
    22141 tgccgttgat aaagaaacga atttcttcat cactcagcgc atgaccatca cgttttttac
    22201 gaataatttc ttgtgcgaga aacaaggtaa cctcccgtgg aaaagagacg aggtaatcgg
    22261 ggaaccggat gagcatcgct gcatcatccg gcaaatcaag ccttagtagc tgctggcgct
    22321 cttaccgtcg ccgtggccca gagctttcag caggcttgcc agcaagctgg aagcaccaaa
    22381 gcggtagtga cgcgcatcag cccagtcagc accgaacagt tcatctgcaa tggcgagata
    22441 tttctgcgca tcttccgcag tacgcacgcc gcctgccggt ttgaaaccaa cggttttttc
    22501 tacgcccata tcgcggatca cttccatcat gatgcgcgcg ctttccggcg tcgcattcac
    22561 agccacttta ccggtagagg ttttgatgaa gtcagcaccc gctttgatgg agatttcaga
    22621 cgctttacgg atcagcgctt cgtctttcag ttcgccggtt tcaataatca ctttcagcag
    22681 tacgttcgcc gcagcgcaag cctctttaca ggctttcacc aggtcaaaac caacctgctc
    22741 gttacctgcc atcagcgcgc ggtacgggaa caccacgtca acttcatcgg caccgtaggc
    22801 gattgccgca cgggtttctg ccagcgcgat ttcgatgtcg tcgttaccgt gtgggaagtt
    22861 agttaccgta gcgatacgga tttccggggt gccctgctct ttcagagttt tgcgagcaat
    22921 cgggataaag cgaggataga tacagatagc ggcggtattg ccgaccggag ttttggcctg
    22981 atgacacagt gcgatcactt tctcatcggt gtcgtcgtca ttcagggtgg tcaggtccat
    23041 caatttcagt gcacgcaggc tgcttgcttt cagatcagtc atttcattct cctggcttgt
    23101 cgccaataaa attcaccttg cgagtttgtt agtattctaa catctactcc gcaacacact
    23161 tcgatgtaca tcacaattaa ggaaatctac ttacaagttt gcatcactgt aatgcgatct
    23221 ggttcaaata attcactttc aaatgaatgc gtcagtggtg gcaaacgcat caggatcaaa
    23281 gtgaacatca cgaaacttct tacaatggcg catcaccttc ggcataaaag gaaaagaaga
    23341 tgcccacttc tcatgaaaat gcactgcaac aacgttgcca gcaaattgtc accagcccgg
    23401 tacttagccc ggagcagaag cgccattttc tggcactgga agcagaaaac aatctgcctt
    23461 acccacagct gcctgccgaa gcccgccgcg cgctggatga gggggtaatc tgcgatatgt
    23521 ttgaaggtca tgcgccgtac aaaccgcgct atgtcttacc cgattacgct cgttttctgg
    23581 cgcacggttc cgaatggctg gagctggaag gcgcgaaaga ccttgatgac gcactctctc
    23641 tgctgaccat tctttaccac catgtaccgt cggtcacatc gatgccggtc tacctggggc
    23701 aactggatgc gttgttgcaa ccgtatgtta gaattctaac acaagacgag atcgatattc
    23761 gaataaaacg tttctggcgt tacctcgaca gaaccctgcc agacgccttt atgcatgcca
    23821 atatcggtcc gtctgattcg cccattaccc gtgcaatatt acgtgcagac gcagagctga
    23881 agcaggtttc accgaacctg acctttatct acgatcctga tatcacccct gatgacctgc
    23941 tgctggaagt ggcgaaaaac gtctgtgaat gtagcaaacc gcacatcgcc aacggtccgg
    24001 tgcatgataa aattttcaca aaagggggct acgggattgt gagctgttac aactcactgc
    24061 cgctggcggg tggtggcagc acgctggtac gccttaacct gaaagccatt gccgagcgca
    24121 gcgaatcgct ggatgacttc tttacgcgca ctctaccgca ctactgccaa cagcagatcg
    24181 ccatcatcga tgcgcggtgt gaattcctct atcaacaatc acacttcttt gagaatagct
    24241 tcctggtgaa agaagggttg attgatcctg aacgttttgt gccgatgttt ggcatgtatg
    24301 ggctggcgga agcggttaac ttgctgtgtg aaaaagaagg gattgccgca cgctacggta
    24361 aagaggccgc cgcaaatgaa gtgggttatc gcattagcgc gcaactggcg gagtttgtcg
    24421 ccaatacccc cgtgaaatat ggctggcaaa aacgcgccat gttacacgca cagtcgggga
    24481 tcagttccga tatcggcacc acgccgggcg cgcgtttgcc atatggtgat gagccagatc
    24541 cgattaccca tctgcaaact gtcgccccgc atcatgctta ttattattcc ggcatcagcg
    24601 acattctgac gctcgacgaa accatcaaac gtaatccgca ggcgctggta cagctttgcc
    24661 tcggtgcctt taaagccgga atgcgtgaat ttaccgccaa tgtcagcggt aacgatctgg
    24721 ttcgcgttac cggttatatg gtgcgtttgt cggatttaga aaaatatcgc gccgaaggtt
    24781 cacgcaccaa caccacctgg ctgggagaag aagccgcacg caacactcgt attctggaac
    24841 gccagccgcg cgtgataagc catgaacagc agatgcgctt tagtcagtaa gattatcccc
    24901 ttctcctgcg ttgacgggcc aggcagtcgt ctggctctgt ttttgcaggg ctgcaatctg
    24961 cgctgcaaaa actgtcacaa tccgtggacg atgggacgtt gcaatgactg tggggagtgc
    25021 gtgccacagt gtccgcatca ggcgttgcag attgttgacg gcaaagtggt gtggaacgct
    25081 gtggtttgcg agcagtgtga tacctgcctg aagaggtgtc cgcaacatgc cacgccaatg
    25141 gcgcaatcca tgagcgtgga cgaagtgctt agccatgtcc gcaaagcggt gctgtttatt
    25201 gaagggataa cggtaagcag cggcgaagcc acgacccaac tgccgtttgt agtggcgctg
    25261 tttactgcta tcaaaaacga tccgcaactg cgccacctca cctgcctggt ggacagtaac
    25321 ggtatgttga gcgaaaccgg ctgggaaaaa ttactcccgg tgtgcgacgg cgcaatgctc
    25381 gatctcaaag cgtgggggag cgaatgtcat cagcaattaa ccggacgcga taatcagcag
    25441 attaagcgca gcatctgttt gctggcagag cgcggtaagc tggcggaact gcgtttgctg
    25501 gtgatccctg gccaggtgga ttatttgcaa cacatcgaag aactggcggc gtttatcaag
    25561 ggactcggcg atgttccggt acgcctgaac gcgtttcatg cccacggcgt gtatggcgag
    25621 gcgcaaagct gggcgagcgc cacgccggaa gacgttgagc cgttggctga tgcgttaaag
    25681 gtgcgcgggg tgagccggtt gatatttccg gcgctctatt tgtgacatgc cggatacggc
    25741 ctacggttcg gcacagactt gtaggcatga taagacgcga caagcgtcgc atcaggcatt
    25801 atgcgccgac tgccggatgc ggcgtgaacg ccttatccgg cctacggttc ggcacagact
    25861 tgtaggcatg ataagacgcg tcagcgtcgc atcaggcatt gtgcgccaac tgccggatgc
    25921 ggcgtgaacg ccttatccgg cctacggttc ggcacagact tgtaggcatg ataagacgcg
    25981 tcaagcgtcg catcaggcat tgtgcgccaa ctgccggatg cggcgtgaac gccttatccg
    26041 gccta
//
LOCUS       DAFGPF010000068        25776 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFGPF010000068 DAFGPF010000000
VERSION     DAFGPF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25776
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.068"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            241..1539
                     /gene="kgtP"
                     /locus_tag="LSX49_003104"
     CDS             241..1539
                     /gene="kgtP"
                     /locus_tag="LSX49_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HBL7169483.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAVLREWGWRIPFALGAVLAVVALRLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPIIGALSDKIGRRTSMLCFGSLATIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAFANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLTLHRKGKGMRL"
     gene            complement(1536..1859)
                     /locus_tag="LSX49_003105"
     CDS             complement(1536..1859)
                     /locus_tag="LSX49_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HBL7169484.1"
                     /translation="MRILFVCSLLLLSGCSHMANDNWSGQDKAQHFIASAMLSAAGNE
                     YSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDFAWDIAGASTGYTVW
                     QLTRH"
     gene            complement(1905..3260)
                     /gene="pssA"
                     /locus_tag="LSX49_003106"
     CDS             complement(1905..3260)
                     /gene="pssA"
                     /locus_tag="LSX49_003106"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HBL7169485.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVNVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWILITGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELDLIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            complement(3374..6034)
                     /gene="pat"
                     /locus_tag="LSX49_003107"
     CDS             complement(3374..6034)
                     /gene="pat"
                     /locus_tag="LSX49_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HBL7169486.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIANLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPGHV
                     AISNPLDLRDDASSEHYVKTLDILLHSQDFDALMVIHSPSAAAPATESAQVLIEAVKH
                     HPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RVHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDIAPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLSLAQREES"
     gene            complement(6066..6764)
                     /gene="tapT"
                     /locus_tag="LSX49_003108"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             complement(6066..6764)
                     /gene="tapT"
                     /locus_tag="LSX49_003108"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HBL7169487.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSHFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLDLVQNP
                     DYQPMVVFPASYADEQREVIFTPPADKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTRAATGLGEHFTRFKTRYLAGKT
                     QHPGSITAEQLESV"
     gene            complement(6833..7252)
                     /gene="trxC"
                     /locus_tag="LSX49_003109"
     CDS             complement(6833..7252)
                     /gene="trxC"
                     /locus_tag="LSX49_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HBL7169488.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            7459..8496
                     /locus_tag="LSX49_003110"
     CDS             7459..8496
                     /locus_tag="LSX49_003110"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HBL7169489.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSQHRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            complement(8544..9233)
                     /gene="ung"
                     /locus_tag="LSX49_003111"
     CDS             complement(8544..9233)
                     /gene="ung"
                     /locus_tag="LSX49_003111"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL7169490.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPI
                     DWMPVLPAESE"
     gene            9538..9921
                     /gene="grcA"
                     /locus_tag="LSX49_003112"
     CDS             9538..9921
                     /gene="grcA"
                     /locus_tag="LSX49_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HBL7169491.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            complement(9977..10564)
                     /gene="eamB"
                     /locus_tag="LSX49_003113"
     CDS             complement(9977..10564)
                     /gene="eamB"
                     /locus_tag="LSX49_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HBL7169492.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLA
                     GMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRQLNIVLALLLVYCAVRIFY"
     gene            10667..11548
                     /locus_tag="LSX49_003114"
     CDS             10667..11548
                     /locus_tag="LSX49_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417072.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7169493.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVISGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDDALNRRELG
                     EQPLVLVASPQIADVDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     ISIESIKRCVAANIGVSYLPRFAVVKELECGELIELPFGEQSQTITAMCAHHAGKAVS
                     PAMHTFIQCVEECFLPG"
     gene            complement(11581..12915)
                     /gene="srmB"
                     /locus_tag="LSX49_003115"
     CDS             complement(11581..12915)
                     /gene="srmB"
                     /locus_tag="LSX49_003115"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HBL7169494.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
     gene            13047..13784
                     /gene="trmN"
                     /locus_tag="LSX49_003116"
     CDS             13047..13784
                     /gene="trmN"
                     /locus_tag="LSX49_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HBL7169495.1"
                     /translation="MSQSTSVFRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADILQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            complement(13769..15391)
                     /gene="nadB"
                     /locus_tag="LSX49_003117"
     CDS             complement(13769..15391)
                     /gene="nadB"
                     /locus_tag="LSX49_003117"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBL7169496.1"
                     /translation="MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVGKAQNHPNIRVLERS
                     NAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTKEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDISRRIPYAHGVSTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSAGNHYINR"
     gene            15647..15802
                     /gene="rseD"
                     /locus_tag="LSX49_003118"
     CDS             15647..15802
                     /gene="rseD"
                     /locus_tag="LSX49_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HBL7169497.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            15799..16374
                     /gene="rpoE"
                     /locus_tag="LSX49_003119"
     CDS             15799..16374
                     /gene="rpoE"
                     /locus_tag="LSX49_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HBL7169498.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            16407..17057
                     /gene="rseA"
                     /locus_tag="LSX49_003120"
     CDS             16407..17057
                     /gene="rseA"
                     /locus_tag="LSX49_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HBL7169499.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            17057..18013
                     /gene="rseB"
                     /locus_tag="LSX49_003121"
     CDS             17057..18013
                     /gene="rseB"
                     /locus_tag="LSX49_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HBL7169500.1"
                     /translation="MKQLWFAMSLVTGSLLFSANALATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDIGSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGTAQ"
     gene            18010..18489
                     /gene="rseC"
                     /locus_tag="LSX49_003122"
     CDS             18010..18489
                     /gene="rseC"
                     /locus_tag="LSX49_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HBL7169501.1"
                     /translation="MIKEWATVVSWENGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFAS
                     DVAALCGAILGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            18687..20486
                     /gene="lepA"
                     /locus_tag="LSX49_003123"
     CDS             18687..20486
                     /gene="lepA"
                     /locus_tag="LSX49_003123"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL7169502.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTEQTYNADRLGIFTPKQIDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRGNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            20502..21476
                     /gene="lepB"
                     /locus_tag="LSX49_003124"
     CDS             20502..21476
                     /gene="lepB"
                     /locus_tag="LSX49_003124"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL7169503.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            21748..22428
                     /gene="rnc"
                     /locus_tag="LSX49_003125"
     CDS             21748..22428
                     /gene="rnc"
                     /locus_tag="LSX49_003125"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBL7169504.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            22425..23330
                     /gene="era"
                     /locus_tag="LSX49_003126"
     CDS             22425..23330
                     /gene="era"
                     /locus_tag="LSX49_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBL7169505.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            23342..24070
                     /gene="recO"
                     /locus_tag="LSX49_003127"
     CDS             23342..24070
                     /gene="recO"
                     /locus_tag="LSX49_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBL7169506.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            24082..24813
                     /gene="pdxJ"
                     /locus_tag="LSX49_003128"
     CDS             24082..24813
                     /gene="pdxJ"
                     /locus_tag="LSX49_003128"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HBL7169507.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVCILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQREKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAATFATSLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            24813..25193
                     /locus_tag="LSX49_003129"
     CDS             24813..25193
                     /locus_tag="LSX49_003129"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBL7169508.1"
                     /translation="MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWEIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVVNMHVTLADERHYACATVIIES"
     gene            25614..25694
                     /gene="shoB"
                     /locus_tag="LSX49_003130"
     CDS             25614..25694
                     /gene="shoB"
                     /locus_tag="LSX49_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HBL7169509.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLLLLFL"
BASE COUNT         6348 a         6396 c         6778 g         6254 t
ORIGIN      
        1 ttatactccc acataagcca gattcaacag cgaatacgtc ttccccaaat tgcccacttc
       61 catacttcct ccttaccaga aatctatcct taagctcctt aataaccatt ttcctgctaa
      121 ctaaattcat ggttaaggtt gtataatgat gcgcaacaaa tgtataacat tttctttacc
      181 aaaaaaaata aacaaaagcg accgacaaaa gcatcggatt acggcaggag acataatggc
      241 atggctgaaa gtactgtaac ggcagacagc aaactgacaa gtagtgatac tcgtcgccgc
      301 atttgggcaa ttgttggggc ctcttcaggt aatctggtcg agtggttcga tttctatgtc
      361 tactcgttct gttcactcta cttcgcccac atcttcttcc cttccgggaa cacgacgact
      421 caactactgc aaacagcagg tgtttttgct gcaggatttc tgatgcgccc aataggcggt
      481 tggctgtttg gccgcatagc cgataaacat ggtcgcaaaa aatcgatgct gttatcggtg
      541 tgtatgatgt gtttcggctc actggttatc gcctgtttgc caggctacga aacaatcggt
      601 acctgggctc cggcattatt gcttctcgcg cgtttattcc agggattatc cgttggcgga
      661 gaatatggca ccagcgccac ctatatgagt gaagttgccg ttgaagggcg caaaggtttt
      721 tacgcatcat ttcagtatgt gacgttgatc ggcgggcaac tgctagctct actggttgtc
      781 gtggttttac aacacaccat ggaagacgct gtactcagag agtggggatg gcgtattcct
      841 ttcgcgttag gagctgtgtt agctgttgtg gcgttgcggt tacgtcgtca gttagatgaa
      901 acttcacaac aagaaacacg cgctttaaaa gaagctggat ctctgaaagg attatggcgc
      961 aatcgccgtg cattcatcat ggttctcggt tttaccgctg cgggctccct ttgtttctat
     1021 accttcacca cttatatgca gaagtatctg gtaaatactg cgggaatgca tgccaacgtg
     1081 gcgagtggca ttatgactgc cgcattgttt gtattcatgc ttattcaacc aattattggc
     1141 gcgctgtcgg ataagattgg tcgccgtacc tcaatgttat gtttcggttc tctggcaacc
     1201 atttttaccg ttcctattct ctcagcattg cagaacgttt cctcgcctta tgccgctttt
     1261 ggtctggtga tgtgcgccct gctgatagtg agtttttata cttcaatcag tggaatactg
     1321 aaggctgaga tgttcccggc acaggttcgc gcattaggcg ttggtctgtc atatgcgttc
     1381 gccaatgcta tatttggtgg gtcggcggag tacgtagcgt tgtcgctgaa atcaatagga
     1441 atggaaacag ccttcttctg gtatgtgacc ttgatggccg tggtggcgtt tctggtttca
     1501 ctaacattgc accgtaaagg aaaagggatg cggctttagt gacgggtcag ttgccagacg
     1561 gtatagccgg tgcttgcacc ggcgatatcc caggcaaaat ccttccagct ccagccgctc
     1621 ccctcagggc ggctatccca aagctctttt gacgccccca gactgacaga gaacatcaat
     1681 ccaaacatgg cactgcgatc ccggctcatc ccctgatgct gtgaatattc atttccggcg
     1741 gcggaaagca tcgccgaggc gataaagtgt tgagctttat cctgcccgct ccagttatcg
     1801 ttagccatat ggctgcatcc agaaagtaac aatagcgaac agacaaaaag aatacgcaaa
     1861 acgtggcctc caaaaaacaa accccgtaca ggacggggtt gtgattacag gatgcggcta
     1921 attaatcggt cgatgcggat acggcgcaaa cggcggatga gtttacgaac cttcaccgga
     1981 taatcggcaa tactttgcag atcgcggtag tgcttaacga tggtggtatg ctcgcggatc
     2041 agatccagtt ctttctctcg ctgtggcgca agctccagtt gcggatcgtg gatcaaaatg
     2101 gcgttttcca gatccagacg ccaggcgcgc gggttcaggt tattaccggt gatcaaaatc
     2161 cacttatcat caacccacat ccctttcagg tgataggtgt tgtcgtcatc tttccataac
     2221 cgaactacta actggtcagt gttgacgtaa tactgtaaac gactcaggaa acgacgcaga
     2281 ttgatctcat agagataagg caatgcgcca attatcttga aaggttcatc ttccggaatg
     2341 tagaagtcat tcgcggtttt atcaccaaca ataatttcga cctttttccc ttcgcgcagc
     2401 aactggataa tattgcgcac aaggattgct ggtaggttga agtaaggtgt gcagatggtt
     2461 agtttctgct cggcacaagg cataagatgg aaaatagtct tgttcaacag actcgatttc
     2521 cccagcccca ctagcggcgt tacggaaagc tgatcgttgt cggcatcgcc ctggaaatga
     2581 taagcggcat cacgcagctc ctggcggaac aggcgaatgt cgttcttgat ttccgggctt
     2641 tttggccgat taacatcatc cagacgatta acgccgcggc cattcataat attctgtgta
     2701 acccattcaa acataatgtc tgacatctta cggttacgga tcagatgata acggtcgtag
     2761 cgatatttat cgtgctgatg caggtaaaca tcgttcaggc tggcaccgct ataaagtacg
     2821 ctatcgtcga tgataaagcc tttaaagtgc agaacaccaa gggcttcacg ggtattgatt
     2881 ggaacgccat aaaccggaac atttacgccc ggattttcct gcgccatgcg gcagtaccag
     2941 tcagcgttag tgttagatgc cgcagcgcca atgcgtccac gttgtgcacg atgccagtcg
     3001 accagcaccc gcacatccag ttccggacgc tgccttttag cctcatacaa cgcgttcaga
     3061 atgcctttgc caccgtcatc ctgttcgaga tacagggcaa caatgcaaat gcgctgcttc
     3121 gcgctggcta ttttttccag caacgtctcc cggaagtcgg cgggagcgta aaagaaatcg
     3181 acatcatcaa ctgattgaga aatcttgggt agttgggcaa ggtgttgttg atgtttatta
     3241 cgcttaaatt ttgacaacat cacagtgcat ttcttctctg ttcattgaag ggtcctctgt
     3301 gcaatgcaga cgacataagc gggcaataat aacaccagtc ccgattaagt ggtcaacatt
     3361 tccagtacct tactcatgat tcctcgcgct gggcaagact tagcgtaagc ccaacgatcc
     3421 cctcttcgag ctggatatca acgttaaacc cgagcttgcg ggccagcgcc accatgccac
     3481 gattgtttgg catcgtaata ccattcagac gttgtagtcc gtgatctcgc gtataggtaa
     3541 tcaacttttc cattaagcgt cgacctaagc ctaacccttt aagatccgag cgaaccagta
     3601 cggcaaattc ggcatcgatg ttatcagggt cggagatcgc acgtgtgacg ccgaggatct
     3661 cttccgtttg atcaattcgt cgtaccgcta caaatgccat ttcccgatcg tagtcgatct
     3721 gcgtcatgtt ggctaaatct tcatgggtaa attcgttgat ctcgctaaag tagcggtaat
     3781 aaagatcttc tttggtgact cgcgaaatga attgctgaag ctgtggctca tcttctggca
     3841 aaatcgggcg gaacaagcag cgttcaccgt ttttcaattc tacccattct tccagctgat
     3901 gcggataagg gcgcacagcc agtcggctct cgttatcacc ttcaaacggc gcgatatcca
     3961 gcgtgacatc cagcgcggta aattcactgc cagaagccag caaaggatga atatccagac
     4021 gctgaatttc cgggcaatcg acaatcaagt tggaaacctg caccagaagc tggctcaagc
     4081 ctgcaacatc caatgggcgt agcgcactgc gcgcacgaat ctttttactt ttgatcccct
     4141 gaataaccag atagcgggcc aggttcatgt tcagcggcgg cagtgcgacg acggcttgat
     4201 cttcaggacg ccactccaca ccgccttcac ccagcatgat caacggcccg aaaaccggat
     4261 cgtgctcaac cacaacccgc aactcctgag cgccagcacg gttagccata ctttgcacca
     4321 acaggccgtg gacccgcgcc tgcggccagg ccatttttac gcgatcgaaa atagcgtttg
     4381 ccgcttgctg gacttcattg gctgtacgta ggtagagcat gacgccctga acttccgatt
     4441 tatgtggaat atccggcgag cgcaatttca gtgccaccgg atagccaatc tgttcggcaa
     4501 tatgtaccgc ttcggtgcta tcactggcaa tccaggtagg gagagtattc ataccatacg
     4561 cttgcaggat gggctgaact tcatgggtat cgagcgacgt agccccttcg gcaatcgcct
     4621 gttgcaacag aagatgcgct tctgcggtat tggaagtcag attgctgggc aacgccggcg
     4681 tttcgcgtag ttgcttctga ttacgccggt actcgaccat atgcataaaa gcagtgatgg
     4741 ttccttccgg agtacggtag gtcggcagcc cggcttcgct gaataaacgt cgtgcctctt
     4801 gcgaggagtg ctcgccgcac cagttcgtca gcaaagagac atatttgctg cggggatgat
     4861 gctttaccgc ttcaattaat acttgcgcgc tttctgttgc gggagcagcg gcgctgggcg
     4921 aatgaataac catcagcgca tcaaaatcct ggctgtggag cagaatgtcc agcgttttga
     4981 cataatgctc gctgctggcg tcatcgcgca gatcgagcgg gttagagatt gccacatgcc
     5041 ctggcagtgc atcgcgcagt ttctggcagg tttcttcgct tagcgttgcc agcttgccat
     5101 tgcgtgacca taaggcatcc agcgccagcg cggcaggcgc agcaccgttg ctgataatca
     5161 tcaaccggtc gccacgcagc gggcgcatat ggctaagggt ttccaccgcc gaaaacagtt
     5221 cgtgggtgtc ctgtacccgc aacaaaccgg cacgctgaat agctgcatcc cacgccggat
     5281 ccattcctgc cgtggtgttc aacagacgtt gagccgccgg gctacgtccg cttttaatca
     5341 ccaaaatcgg tttattgcgc gaggcactac gggctgccga aacaaagcgt cgcgcgtcgc
     5401 ttaactgttc gagatagagc aggatggcgc tggttttact gtcgcgcgcc agatagtcga
     5461 gcaattcatc aacgtcgata tccaggctgt cgccgagcgc aataaagtag gaaaagccca
     5521 tctcacgctg ttgcgcccag tcgaggatgg tgttggagac agcagccgat tgcgaaataa
     5581 acgccagctt gccgcgttta atcggcacag gcgaaaagct ggcattcaga ccttgccagg
     5641 gagccagtaa gcccagactg tttggtccta gcaggcgcat gttatggcgc agggcgcagg
     5701 cgcggagatc ttcgtgttgc gatgccgggg cggaaagaat aatgcaggtt ttacagcctt
     5761 tctcgccgag ctcttccaga agagcaagat tacggctggc attggtacat aaaaccgcaa
     5821 ggtcgggtgt aaagggcaag ttggcaatat ccggccaggc caacacaccc aacaccgctt
     5881 tccaggctgg cgtcaccggg agtaccggtc cgttaaagcc tcccgccagc aggttacgca
     5941 tcatcaggta acctgcgcga ttgggtttca tcgatgcgcc aattaccgca atcgattttg
     6001 gtcgcagtag tgcttccagt cctcgctgac tcataccggt ctcccgcaga agtgaccgaa
     6061 tgattttaaa cgctttctaa ctgttctgct gtgatgcttc ccggatgttg cgtttttcct
     6121 gccagatagc gtgttttaaa gcgggtaaaa tgctcgccta accctgtcgc cgccctggta
     6181 tcgccggcca tatctaacag tgcgatggct acctcggcag tacaatattg gccttcagcc
     6241 tgggcttcac gcaggcgata ggcagaaagc cgagaaagat cgacggaaat gacgggaaga
     6301 ttatccagat acggactttt acgaaacatc ttgcgagctt ctggccaggt accatcgagc
     6361 atgataaata gcggaggctt atcggcaggt ggtgtgaaga tcacttcccg ttgctcatca
     6421 gcatacgaag cgggaaagac caccattggc tgatagtctg ggttttgcac cagatccagc
     6481 aaatcttgcg agggttcggt acgcgaccat tgaaacgcaa cggtatcagg caaaatatca
     6541 gcaatcagac gcccggtatt actgggcttc attggctcgg tgtcgaacat cagcaaacag
     6601 aagtgacttt ttgcttgtgc tggggtaatt gtcgaacaga gacataattt ctctggcaaa
     6661 agacagcgtt ggcagcgacg aacgcgatta ccgcgggcaa gaaaaggacg tgttgcgcgc
     6721 gcaatacgct cggcgcgtaa ctggagaaca gcgttttcgg tcataagaga gcgtcgaaaa
     6781 aacgccattg tcgcagagga gaaaacgggg cacaagatgc gccccggtaa gattaaagag
     6841 attcgttcag ccagctgtcg aacggcgctt tcggtactgc gccattaagc atgtcgacaa
     6901 cctgaccgtt tttgaaaatc atgatcgtcg gtatactacg aattccaaag cgactgctca
     6961 attcacgttc agcttcggta ttcactttca caaagcgcac tttaccgcta cgctcttgcg
     7021 cgacatcttc aaaaattggt gcgaaattac ggcaggggcc gcaccacggt gcccagaagt
     7081 cgatcaccac aggtagatca tctttcagca atttgtcgag cgtttcaccg gtcgcattaa
     7141 tcacctctcc gtcaaacaag tcgtgaccgc agcgtccgca ttttgccgca tcttcgatcc
     7201 gatcgtcggg aatgcgattg atggcctgac aatgggtaca aacggtattc ataactaacc
     7261 tcgggatgag taaggagact tatcggcaac gacgccggta tgtttctaat atgttacata
     7321 ttatcgggga cattgttcca gacaacaatc tgttttattc aatgggtatg atagacacag
     7381 gctttggaac gaaatcatgg cgaaccgcgc gcacttcggg taatctgcgc gcttcgcgca
     7441 gcgctggtgg agaaaagcat gaacgatgaa atgaaaggta aaagcggcaa ggtcaaagtg
     7501 atgtatgtcc gcagtgatga tgattctgat aaacgtaccc acaacccgcg taccgggaaa
     7561 gggggcgggc gtccaggaaa atctcgtgct gacggtggcc gtcgccccgc ccgcgatgac
     7621 aaacagagtc agcaccgtga ccgcaagtgg gaagattcgc cgtggcgcac ggtttcccgc
     7681 gcgccgggtg atgagacgcc ggaaaaggcc gatcacggtg gcatcagtgg taaaagtttt
     7741 attgatccgg aagttttgcg tcgtcagcgt gcggaagaaa cccgcgtcta cggcgaaaac
     7801 gcctgtcagg cactgttcca gagccgtccg gaagcgattg ttcgcgcctg gtttatccag
     7861 agcgtaacgc cacgttttaa agaagccttg cgctggatgg cggcaaaccg caaagcgtac
     7921 catgtggtgg atgaagcgga actgacaaaa gcgtcaggca cggaacatca cggcggcgtt
     7981 tgcttcctga tcaaaaagcg taacggtaca accgtgcagc agtgggtaag ccaggcaggc
     8041 gcgcaggatt gtgtactggc cctggaaaac gaatctaacc cgcataacct gggtggcatg
     8101 atgcgtagct gtgcgcactt cggcgtgaaa ggtgttgtgg tgcaggatgc agcactgctg
     8161 gagtctgggg cggctatccg taccgcagaa ggcggcgcag agcacgttca gccgattact
     8221 ggcgacaaca ttgttaacgt gctggatgat ttccgtcagg cgggttacac cgtagtgaca
     8281 acttccagcg agcagggtaa accgctgttc aaaaccagtc tgccagcgaa aatggtactg
     8341 gtgctgggtc aggaatatga agggttaccg gatgccgcac gcgatccgaa cgatctgcgc
     8401 gtgaagattg atggtactgg caacgttgcc gggctgaata tctctgtcgc aaccggcgtt
     8461 cttcttggcg aatggtggcg tcagaataaa gcctgataaa tcagccgggt ggcaactctg
     8521 ccatccggca ttttcccgca aatttactca ctctctgccg gtaatactgg catccagtca
     8581 atcggcgtct cgccacgttg ttccagccac tgatttgcca gcacaaaatg gttgcagcca
     8641 aagaatccac gatgcgccga aagcggcgac ggatgcggtg ctttcagtac atgatggcgt
     8701 tgcttatcta taatcgcccc tttcttttgc gcatgtgatc cccacaacaa aaacaccacg
     8761 ccttcgcgat gctgatttat gaggctgatg actttatcag taaacgtctc ccagccgagg
     8821 ctggcgtggg aatgcgcctg accagcgcga accgtcaaga cggtattgag cagcagaaca
     8881 ccctgacgcg cccagctttc aagataacca tgattagggc gggtgaaacc gggaatagta
     8941 ttttccagct ctttatacat attcagcagt gacggtggtg tcgcaatgcc ggggcgaacg
     9001 gaaaatgcca gaccatgcgc ctgtcctggt ccgtgataag gatcctgacc gagaatcacc
     9061 actttaacgt cacccaactc cgtaaagcgg aacgcgttaa agacatcttt ttgtggtgga
     9121 tagatagtga cgccggactg ccgctcgctg gcgacggtct gaagggtatt aagaaaatag
     9181 ggttgctgct tctcttcagc cagcacatca tgccaggtta attcgttagc catctcgctc
     9241 tcctgcgaat ctttaatccg cctagcttaa ctgcttcttt ctacagaaca aaatcatgct
     9301 cattttatag acaaaaagac atgcaaaaaa atgtaaattg gtaaaatttc acatctgcat
     9361 aagttgatgt aaaacaataa aatccatttg tgaccacact tgatatgtgg tttttattga
     9421 tttaaatcaa agaatcaagg gtgtttgagg agtatatata cactcaagca acaatggttt
     9481 taccaattgg ccgcgacagg ctgaacaaat caaataattt tgccggggag gcatcacatg
     9541 attacaggta tccagattac taaagccgct aacgacgatc tgctgaactc tttctggttg
     9601 ctggacagcg aaaaaggcga agcgcgttgc atcgttgcga aagcaggttt tgcagaagac
     9661 gaagtggttg cagtaagcaa actgggtgac attgaatacc gtgaagttcc agtagaagtg
     9721 aaaccagaag ttcgcgttga aggtggtcaa cacctgaacg ttaacgttct gcgtcgtgaa
     9781 actctggaag atgcagttaa gcatccggaa aaatatccgc agctgaccat ccgtgtatcc
     9841 ggttatgcag ttcgctttaa ctctctgact ccggaacagc agcgcgacgt tatcgctcgt
     9901 acctttactg aaagcctgta aggcttaagt agcaagttac taagcggaag agggcgacct
     9961 cttccgcttt ttttcgttaa tagaaaatgc gtaccgcgca atagaccagc aacagggcaa
    10021 gcacgatatt taactggcga ccatactggc gaaacaatcg ctgaaacaga tgccccgcca
    10081 gcgcccagca cacattgcca aacgtcccaa tcatcgccag caaaacgctg acgccaacta
    10141 cccagcttag cgcctgtgtt tgcggcagaa caaacgtcga cagtgccgta acaccgtaca
    10201 aaatgatttt gacgttcaca aactgcaaag caaagctggc ccaaaagctg attggttttg
    10261 cctgaagtcc gtcttccttt gttgggctgg tggcgatttt ccacgccagc cagacaatat
    10321 atgccgcccc cgcccaactc aaaaggtgta ccgctgccgg gtcaatcact gccagtgaaa
    10381 atgaaatgcc cgcacacagt aacatcacaa tcaaaaatcc cagactcatc cctgccagca
    10441 cacgggtact ttgacgaaat ccatgcgacg tagcagagct aagggcgaga atattgttcg
    10501 gtcctggcgt catggcggta atcagggtgt aagtccaaaa agcacttaaa agggtcggtg
    10561 tcacttgtta tctcctctgt tttggtagac agtacccgac acggaacatt taaaaaaatg
    10621 aatgttttta cattctaaat tcgatatttt cgataggttt ggggttatgg atctgcgccg
    10681 ttttattacg cttaaaaccg tggtggaaga gggttccttt ttgcgagctt cgcaaaaatt
    10741 gtgctgtaca caatcgacgg tgacttttca tattcagcag cttgagcagg agttctcggt
    10801 acaattgttt gagaaaattg gtcgacgaat gtgccttacc cgcgaaggaa aaaagctgct
    10861 gccgcacatc tatgaactta cccgagtgat ggatacgctt cgtgaggctg ctaaaaaaga
    10921 gtcggatccg gacggggaac tacgcgttat ttcaggcgaa acgttgctct cttatcgaat
    10981 gccgcaggtg ttgcagcgtt ttcggcaacg cgctccaaaa gtgcgtttat cgttgcagtc
    11041 gctgaactgt tacgtgatcc gtgatgcgct actgaatgat gaggccgatg tcggggtttt
    11101 ttatcgcgta gggaatgatg atgctctgaa ccgacgagag ttgggtgaac aaccgctggt
    11161 gctggtggct tcaccgcaaa ttgcagatgt cgattttact gagccgggaa gacataacgc
    11221 ctgtagcttt attatcaacg aaccacaatg tgtcttccgg cagatatttg agagcacgct
    11281 gcgccagcgg cggatcacgg tggaaaacac cattgagctt ataagtatcg aaagcatcaa
    11341 gcgttgtgtc gcggcaaata tcggagtcag ttacctgccg cgttttgcgg tagtaaaaga
    11401 gttggagtgc ggagaattaa ttgaattgcc ttttggcgaa cagtcgcaga ccattacggc
    11461 aatgtgcgct caccatgccg gaaaagcggt tagcccggcg atgcacactt ttattcagtg
    11521 tgttgaagag tgttttttgc cgggataaaa acaatgccgg gcttaaaccc ggcattgaga
    11581 ttactcttct gtcgtttgcg gtggcacgcc cgttccgctt ggtttacggc gcttaccaat
    11641 atttttagtg tcgcgatggc gttttttcac ccgcggcttc tctttctctt tagctttttt
    11701 cttctcggca cgtttagcca acactttctt cgatggcttg ccggtctgct tctcgcttgg
    11761 cgcacgcgtt ttcggacgta actcatcaat tacgcgagct ttaattggct cttcaatata
    11821 acggccaact ttgcccagta gcagatggtc atgggcttcc accagcgaaa tcgcggtgcc
    11881 tttacgaccg gcgcgcgcgg tacgtccgat acggtgcaaa taagtatcgc cactgcgcgg
    11941 catatcgaag ttaaagacgt ggctgacgtc aggaatgtcg ataccgcgcg cggcaacatc
    12001 ggtagcaacc agtacgttta cgcggccttc ggtcaagcgt ttaatcgctt cgttacgctt
    12061 gccttgtacc atctcacctt cgagatagca gttgttgatg cctgcttcgc gcagccagtt
    12121 tgccagctca tgcacacgct cacgcttacg cacaaacaca attgagcggg tcgcttccgg
    12181 ctgttttaac agatgcacca gcaacgcggt tttatgctca agatcatcgg cgcggtaata
    12241 ccactgatga atttttttgc gctcacgggt ggacggattg gcagaaactt ccaccggatc
    12301 ttccaacaga cgctcggcaa agtcctgaat cgcatcgcct tccagcgttg ccgaaaagag
    12361 cagggtctgt ttacgccagc gcgtttcgcc agcaatatgt tcgatatcct gggcgaagcc
    12421 catatccagc atacggtctg cttcgtcgag gatcagcgtt tcaaccgcgc ggcaatcgaa
    12481 gttctcttct tttatgtatt gcagcagacg tccggtcgtg gcgaccacaa tgtcctggtt
    12541 ttcgctgaac acttctgcgt ggttcatata ggccacgccg ccggtgatgg tggcaatatc
    12601 cagatgcgta tgtttcgcca gttcgcgggc atgatcggcc acctgcatcg ccagctcgcg
    12661 agttggggtg aggatcaaaa tacgcggcgg accggatttc ttacgtggga aatcgagcag
    12721 gtgctgcaac gctggcagca gatacgccgc cgttttaccg gtgcctgtcg gcgcagaacc
    12781 gagtacatca cggccatcga gcgcaggcgg aatggcggca gcctgaatgg cggtcgggcg
    12841 agtgaaacct ttatcctgga gggcttccag caggctttcg tcgagttcaa gttcggaaaa
    12901 agtcgttaca gtcatgttct acctctgtgt ggggcgctga ttatagacgt tacggctgca
    12961 atcttcatct gtttgtatgg atatcgcttc tcgggtattg ttctcacccg gtgctatcgc
    13021 cgtttttcct gcaaggtttt attttcatgt cacagtctac atccgtgttt cgtcgtaatg
    13081 gatttacttt taaacagttt tttgttgctc acgatcgctg tgcgatgaaa gtgggaacgg
    13141 atggcatttt gctgggcgca tgggcaccgg tagctggggt aaaacgttgc cttgatatcg
    13201 gcgcgggtag cgggttgctg gcattaatgc tggcgcagcg aacagatgac agcgtgatga
    13261 ttgatgcagt tgaactggaa agtgaagctg ccgcgcaagc gcaggaaaat atcaaccagt
    13321 ccccgtgggc agagcggatt aatgtccata cggcggatat tctgcagtgg atcacacagc
    13381 agacagtacg cttcgattta atcatcagca acccacctta ctatcagcag ggagtagagt
    13441 gcgcgacacc tcaacgggaa caggctcgct ataccactac gcttgatcac ccatcgttgc
    13501 tgacttgtgc ggcggagtgc attaccgaag agggattttt ctgcgtggtg ctgccagagc
    13561 agattggtaa tggttttact gaactggcat taagtatggg ctggcattta cgtttgcgga
    13621 cggatgtggc ggaaaacgaa gcgcgactgc cgcatcgggt gctgctggca ttctccccgc
    13681 aggcgggaga gtgctttagc gatcgcttag tcattcgtgg gccagaccag aactattccg
    13741 aagcgtatac ggcgctgacc caggcttttt atctgtttat gtaatgattg ccggcagaaa
    13801 ggatcgatgg accggaatgc gtgagcagtt ccggataatc cagcgtgaaa tgcaggccac
    13861 ggctctcctt gcgcatcatc gcacagcgaa caatcaactc ggcaacctgt accagattac
    13921 gcagctccag caaattattt gagacgcgga aatgggcgta atattcgtct atttcttgtt
    13981 ggagcatggt tatccgccgc agggcgcgtt ccaggcgctt cgttgtgcga acaatgccaa
    14041 cgtaatccca cataaacaga cgtagctcgt gccagttatg ctgaattact acccgttcgt
    14101 cagggttctc aacgcggctt tcatcccacg gcggtaacgt actgacgccg tgggcataag
    14161 gtatacgtct gctgatatct tctgccgccg accagccata gaccagacac tccagcaatg
    14221 aattcgaggc catgcggtta gcgccgtgta agccggtata actcacttcg ccaatggcat
    14281 acaaaccctc gacgtccgta cgcccatgat catcaaccat tacaccaccg caggtataat
    14341 gtgcagcagg cacaatcggc acgggttctt tcgtgagatc tatccccagc ccgagcaatt
    14401 tttcataaat catcgggaaa tgctggcgaa taaaatcggc gggcttatgg ctgatgtcga
    14461 ggaacataca atctgcgccg aggcgtttca tttcatggtc aatggcgcgg gcgacaatat
    14521 cgcgcggggc cagttcgccg cgctcatcaa aatcgggcat aaaacgcgtg ccatccgggc
    14581 gcttgagata agcgccttcg ccgcgcagtg cttccgttaa caggaaattg cgtgcctgtg
    14641 ggtgatacag cgcggtaggg tggaactgat taaattcgag attggcaacc cggcagcctg
    14701 cgcgccacgc catagcaatg ccatcgccag aagaaatatc cggattggtg gtgtactgat
    14761 aaacttttga agcaccgccg gttgccagta ccactgcttt tgcgtggcag gtttcaaccg
    14821 tttctttatt tcggttccat acccacgcgc caacaacccg tcgcgtgccc ggcaggccaa
    14881 ttttgtcaga aacaatcaga tcaaccgcgt tgctgcgctc cagcacgcga atattcggat
    14941 ggttctgcgc cttgcccacc agcgtggttt ctacttctct accggtggcg tcggcggcat
    15001 gaagaatacg acggtgacta tgtccacctt cacgagtcag atggtagctt tcttcgccat
    15061 tcggctgaat gtgggtatca aacaacaccc cctggtcgat tagccattgc acacaggatc
    15121 gtgcattact ggcgacaaat tcaactgcat ggcgatcgca aataccagcc ccggcaatca
    15181 atgtgtcttc cacatgcgag tcaatgctgt cagtttcatc aaacacggcg gcaataccgc
    15241 cctgggcata aaatgttgaa ccttccgtta ccgggccttt acttagaacg atgacctgat
    15301 gctggtcagc caggcgtagc gccagtgaaa gtccagctgc gccgctaccg ataatcaaca
    15361 cgtcacatga atgttcaggg agagtattca ttttctttgt ttaatttact aaacactgtt
    15421 tggtcagcat aacatcatgt tgtgcaaata aacacctgct attttaatat ttgttacagt
    15481 gactaaacac gctggctcag ggcggcgaga aaaagagaag ttactggctg gtggaggatt
    15541 aggtggtgaa ataaaaaggc cgttgggtta ctcttcaggc agttaaatgg gcatttctac
    15601 acagataatg cgatgttcag attctgtaga cttataatga tagataatga tccgtctaca
    15661 gcatgacaaa caaaaacaga tgcgttacgg aactttacaa aaacgagaca ctctaaccct
    15721 ttgcttgctc aaattgcagc taatggagtg gcgtttcgat agcgcgtgga aatttggttt
    15781 ggggagactt tacctcggat gagcgagcag ttaacggacc aggtcctggt tgaacgggtc
    15841 cagaagggag atcagaaagc ctttaactta ctggtagtgc gctatcagca taaagtggcg
    15901 agtctggttt cccgctatgt gccgtcgggt gatgttcccg atgtggtaca agaagctttt
    15961 attaaagcct atcgtgcgct ggattcgttc cggggagata gcgcttttta tacatggctg
    16021 tatcggattg ctgtaaatac agcgaaaaat tacctggttg ctcaggggcg tcgtccacct
    16081 tccagtgatg tggatgccat tgaagctgaa aacttcgaaa gtggcggcgc gttgaaagaa
    16141 atttcgaacc ctgagaactt aatgttgtca gaagaactga gacagatagt tttccgaact
    16201 attgagtccc tcccggaaga tttacgcatg gcaataacct tgcgggagct ggatggcctg
    16261 agctatgaag agatagccgc tatcatggat tgtccggtgg gtacggtgcg ttcacgtatc
    16321 ttccgagcga gggaagctat tgataacaaa gttcaaccgc ttatcaggcg ttgacgatag
    16381 cgggatactg gataagggta ttaggcatgc agaaagaaca actttccgct ttaatggatg
    16441 gcgaaacgct ggatagtgag ctgcttaacg aactggctca taacccagaa atgcagaaaa
    16501 cctgggaaag ctatcactta atccgtgact caatgcgggg tgatactccc gaggtgctcc
    16561 atttcgatat ctcttcacgc gtgatggccg ccattgaaga agagccagta cgtcaaccgg
    16621 cgacattgat cccggaagcc cagcctgcgc cgcatcaatg gcagaaaatg ccattctggc
    16681 agaaagtacg tccgtgggcg gcacagctta cccaaatggg cgtagcagca tgcgtatcgc
    16741 ttgcagttat cgttggcgtc cagcactata atgggcaatc tgaaacgtcc cagcagcccg
    16801 aaacgccagt atttaataca ctgccgatga tgggtaaagc cagcccggtt agtctgggag
    16861 taccttctga agcgaccgca aataatggtc aacagcagca ggtacaggag cagcgtcgtc
    16921 gcattaatgc aatgttgcag gattacgaac tgcaacgccg actccactct gaacagcttc
    16981 agtttgagca ggcacaaact cagcaagccg ctgtacaggt gccaggaatt caaactttag
    17041 gaacgcaatc gcagtaatga agcaactttg gtttgccatg tcattagtga caggtagcct
    17101 gttattctct gctaacgcct tggccactcc cgcgtccggg gcgttattac agcagatgaa
    17161 cctggccagt cagtcactga attacgagct gtcatttatc agcatcaata aacagggtgt
    17221 tgagtctctg cgttatcgac atgcacgcct cgataaccgt cctcttgcac aattgttgca
    17281 aatggatggc ccgcgccggg aagtggtaca gcgcggcaat gaaatcagct attttgaacc
    17341 gggacttgaa ccgttcacgc ttaatggcga ttacattgtt gattctctgc catcgctcat
    17401 ctataccgat ttcaaacgcc tttctcctta ctacgacttt atctctgtcg ggcgcacgcg
    17461 tattgctgat cgtctttgcg aagtcattcg tgtggttgcc cgagatggta cacgctacag
    17521 ctacatcgtg tggatggaca ccgaatcgaa attaccgatg cgggttgatc tccttgatcg
    17581 cgatggtgaa acgctggaac aatttcgcgt gattgctttt aacgtcaatc aggatatcgg
    17641 cagcagtatg cagacgctgg cgaaggcaaa tttgccgccg ttgctttctg ttcctgttgg
    17701 tgaaaaagct aaattcagct ggacgccaac ctggctgcca cagggtttta gcgaagtttc
    17761 cagtagtcga cgtccgctac cgacgatgga caacatgcct atcgaatcac gtctctattc
    17821 cgacggatta ttcagcttct cggtaaacgt taaccgcgct acgccatcga gcaccgatca
    17881 gatgttgcgc accggacgca gaaccgtcag tacaagcgta cgtgataacg ccgaaatcac
    17941 cattgttggt gaactgccgc cgcaaacggc gaaacgcatt gccgagaata ttaagttcgg
    18001 gacagcgcaa tgatcaaaga gtgggctacc gtcgtctcct gggaaaacgg gcaggcgctg
    18061 gtcagttgtg atgttaaagc ctcatgcagc agctgcgctt cacgcgccgg ttgcggtagc
    18121 cgtgtgttga ataaacttgg cccgcaaacc acgcatacca ttgtcgtacc ctgtgatgag
    18181 ccgctagtgc cggggcaaaa agtggaattg gggatcgccg aaggcagcct tcttagctcc
    18241 gcattactgg tttatatgtc gccgctggtg ggattattcc tcatcgcttc gctatttcag
    18301 ctactctttg cttctgacgt cgcagcatta tgtggtgcga tcctcggcgg tattggtggg
    18361 ttcctgattg cgcgcggcta ttcgcgtaag tttgctgccc gggcagaatg gcaaccgatc
    18421 atcttaagcg tggcattgcc gcctggcctt gtgcgatttg aaacatcttc ggaagacgcg
    18481 agccagtgat ttcactggct ttgttgcatt ttgcataaca aatgcgagga cgtttccata
    18541 taccacaatc catacggtat gaacatttcc tcgcctcaat gttgtagtgt agaatgcggc
    18601 gtttctatta atacagacgt taagctcaga acagcgactt ctaaaagcct ggttaaccgg
    18661 gcattaaggc acaataatca tactttatga agaatatacg taacttttcg atcatagctc
    18721 acattgacca cggtaaatcg acgctgtctg accgtattat ccagatctgc ggtggcctgt
    18781 ctgaccgtga aatggaggcg caggttctcg attccatgga tcttgagcgt gagcgtggca
    18841 ttaccatcaa agcgcaaagc gtgacgctgg actacaaagc gtctgacggc gaaacctatc
    18901 agcttaactt tatcgacacc ccgggccacg tagacttctc ctatgaagtt tctcgttcgc
    18961 tggctgcctg tgaaggtgca ttgctggtgg tcgacgccgg gcagggcgta gaagcgcaaa
    19021 ccctggcaaa ctgctacacc gccatggaaa tggatctcga agtggtgccg gtactgaaca
    19081 agattgacct gccggcagcc gatcctgaac gcgtggcgga agaaattgaa gatatcgtcg
    19141 gcatcgacgc caccgacgcg gtgcgctgtt cagcgaaaac cggcgttggc gtgcaagacg
    19201 ttctcgaacg cttggtgcgc gacattccgc cgccggaagg cgatccggaa ggcccattgc
    19261 aggcgctgat tatcgactcc tggttcgaca actacctggg cgttgtttca cttatccgta
    19321 ttaaaaacgg caccctgcgt aagggcgaca aagtgaaagt catgagcacc gagcagacct
    19381 ataacgccga tcgtctgggc atcttcacgc cgaagcagat tgaccgcact gaactgaaat
    19441 gtggcgaagt aggctggctg gtatgtgcga ttaaagatat ccacggcgct ccagtaggcg
    19501 ataccttaac actggcgcgt aatccggcag aaaaggcgct gcctggcttt aagaaagtca
    19561 aacctcaggt atatgctggt ctgttcccgg taagttccga cgactatgaa gccttccgtg
    19621 acgcgctggg taaactcagc ctgaacgatg cctcactgtt ctatgagccg gaaagctcca
    19681 gcgcgttggg ctttggtttc cgctgcggct tccttggcct gctgcacatg gagatcatcc
    19741 aggaacgtct ggaacgtgaa tacgatctgg atctgatcac cactgcgccg actgtagtgt
    19801 atgaagttga aaccacgtca agagaagtta tctacgtcga cagcccatcc aagctgccag
    19861 cggtaaataa catttacgaa ctgcgcgagc cgattgcaga gtgtcacatg ctgctgccgc
    19921 aggcatatct cggcaacgtt attacgctgt gcgtagaaaa acgcggcgtg cagaccaata
    19981 tggtttacca cggtaatcag gtggcgctga cgtacgagat cccgatggcg gaagtggtgc
    20041 tcgacttctt cgatcgcctg aaatctacct cgcgtggtta tgcgtctctg gattacaact
    20101 tcaaacgctt ccaggcgtcc gacatggtac gtgtagacgt attaatcaac ggtgaacgtg
    20161 ttgatgcatt ggcgctgatc acccaccgtg gtaattcgca aaaccgcggt cgcgagctgg
    20221 tggagaagat gaaagatctg atcccacgcc agcagtttga tatcgccatt caggcagcga
    20281 ttggtacgca catcattgcg cgctccaccg tgaaacagct gcgtaaaaac gtactggcta
    20341 aatgttatgg cggcgatatc agccgtaaga aaaagctgct gcagaagcag aaagaaggta
    20401 agaaacgcat gaagcagatc ggtaacgtcg agctgccgca ggaagcgttc ctcgccattc
    20461 tgcacgtcgg caaagacaac aaataaccct taggagttgg catggcgaat atgtttgccc
    20521 tgattctggt gattgccaca ctggtgacgg gcattttatg gtgcgtggat aaattctttt
    20581 tcgcacctaa acggcgggaa cgtcaggcag cggcgcaggc ggctgccggt gactcactgg
    20641 ataaagcaac gctgaaaaag gttgcgccga agcctggctg gctggaaacc ggtgcttctg
    20701 tttttccggt actggctatc gtattgattg tgcgttcgtt tatttatgaa ccgttccaga
    20761 tcccgtcagg ttcgatgatg ccgactctgt taatcggtga ttttattctg gtagagaagt
    20821 ttgcttatgg cattaaagat cctatctacc agaaaacgct gatcgaaacc ggtcatccga
    20881 aacgcggcga tatcgtggtc tttaaatacc cggaagatcc aaagcttgat tacatcaagc
    20941 gcgcggtggg tttaccgggc gataaagtca cttatgatcc ggtctcaaaa gagctgacga
    21001 ttcaaccggg atgcagttcc ggccaggcgt gtgaaaacgc gctaccggtc acttactcca
    21061 acgtggaacc gagcgatttc gttcagacct tctcacgccg taatggtggg gaagcgacca
    21121 gcggattctt tgaagtgccg aaaaacgaaa ccaaagaaaa tggaattcgt ctttccgagc
    21181 gtaaagagac actgggtgat gtgacgcacc gtattctgac agtgccgatt gcgcaggacc
    21241 aggtggggat gtattaccag cagccagggc aacaactggc aacctggatt gttccgccgg
    21301 gacaatactt catgatgggc gacaaccgcg acaacagcgc ggacagtcgt tactggggct
    21361 ttgtgcctga agcgaatctg gtcggtcggg caacggctat ctggatgagc ttcgataagc
    21421 aagaaggcga atggccgaca ggtgtgcgct taagtcgcat tggcggtatc cattaatagc
    21481 catcttcgtt cacgttgtcg ccgttatggc gacaacgtga attatttatg agataaatct
    21541 cccgtggcta acgacatccc ccgtcgttgt gtatagaata ttcccccgaa gtttaaggtt
    21601 ggcacctcca ggttgccacg gcacacgaaa cagcgttggt ccccatatac cggtaaactg
    21661 aaactgcagt gaagcagtta gccgagccat gtatatcagg tctgtttcgt gtgctgaatt
    21721 gttgacgcat ttatttattg gtatcgcatg aaccccatcg taattaatcg gcttcaacgg
    21781 aagctgggct acacttttaa tcatcaggaa ctgttgcagc aggcattaac tcatcgtagt
    21841 gccagcagta aacataacga gcgtctggaa tttttaggtg actctattct gagctacgtt
    21901 atcgccaatg cgctttatca ccgtttccct cgtgtggatg aaggcgatat gagccggatg
    21961 cgcgccacgc tggtccgtgg taatacgctg gctgaactgg cgcgcgaatt tgagttaggt
    22021 gagtgcttac gtttagggcc aggtgaactt aaaagcggtg gatttcgtcg tgagtcaatt
    22081 ctcgccgaca ccgtcgaagc attaattggt ggcgtattcc tcgacagtga tattcaaacc
    22141 gtcgagaaat taatcctcaa ctggtatcaa actcgtctgg acgaaattag cccaggcgat
    22201 aaacaaaaag atccgaaaac gcgtctgcag gaatatttgc agggtcgcca tctgccgctg
    22261 ccaacttatc tggtagtcca ggtacgtggc gaagcgcacg atcaggaatt tactatccac
    22321 tgccaggtca gcggcctgag tgaaccggtg gttggcacag gttcaagccg tcgtaaggct
    22381 gagcaggctg ccgccgaaca ggcgttgaaa aaactggagc tggaatgagc atcgataaaa
    22441 gttactgcgg atttattgct atcgtcggac gtccgaacgt tggcaaatcc acattgttga
    22501 acaaactgct ggggcagaag atctccatta cctcccgcaa ggcgcaaaca actcgtcacc
    22561 gcattgtggg gatccatact gaaggcgcgt atcaggcgat ctacgttgat accccaggcc
    22621 tgcatatgga agaaaaacgc gccattaacc gtctgatgaa caaagcggcg agcagctcca
    22681 ttggcgatgt tgagctggtg atttttgtcg tagaaggcac tcgctggacg ccggacgatg
    22741 aaatggtgct caacaaactg cgcgatggca aagcgccggt aatcctcgcg gtgaacaaag
    22801 tggataatgt gcaggaaaaa gccgatctgc tgccacactt acagttcctg gcaagccaga
    22861 tgaacttcct cgatatcgtg ccgatctctg ccgaaaccgg gctgaatgtc gacactattg
    22921 cagcaatcgt gcgtaagcat ctgcctgaag cgacccatca cttcccggaa gattacatca
    22981 ccgatcgctc acagcgtttt atggcgtctg aaattatccg cgaaaaactg atgcgttttc
    23041 tcggcgctga actgccgtac tccgtgaccg tggagatcga acgtttcgtc tctaacgaac
    23101 gcggcggtta tgacatcaac ggtttgattc tcgttgagcg tgaagggcag aagaagatgg
    23161 tcattggcaa caaaggggcc aagatcaaaa ccatcgggat tgaagcgcgt aaagacatgc
    23221 aggaaatgtt cgaagcgcct gttcaccttg agctgtgggt aaaagtgaaa tccggttggg
    23281 ccgacgacga acgcgcactg cgcagtctcg gttatgttga cgatctttaa gagtaactcc
    23341 gatggaaggc tggcagcgcg catttgtcct gcatagtcgc ccgtggagcg aaaccagcct
    23401 gatgctggac gtcttcacgg aggaatcggg tcgcgtgcgt ctggttgcca aaggcgcacg
    23461 ctctaaacgc tctactctga aaggtgcatt acagcctttc acccctctct tgctacgttt
    23521 tggcgggcgt ggcgaagtca aaacgctgcg cagtgctgaa gctgtctcgc tggcgctgcc
    23581 attaagcggt atcacgcttt acagcggtct gtacatcaac gaacttctct cccgcgtact
    23641 ggaatacgag acgcgcttct ctgaactctt tttcgattac ttgcactgca ttcagtctct
    23701 tgccggggtc actggtacgc cagaacccgc gttgcgccgc tttgaactgg cactgctcgg
    23761 gcatctgggc tatggcgtca attttaccca ttgtgcgggt agcggcgagc cggtagatga
    23821 caccatgacg tatcgttatc gcgaagaaaa agggtttatc gcaagcgtcg ttatcgacaa
    23881 taaaacgttc accggaaggc agttaaaagc gttaaacgcg cgggaatttc ctgacgcaga
    23941 cacactgcgc gccgcgaaac gctttacccg catggcgctt aagccgtatc ttggcggtaa
    24001 accattaaag agcagggaac tgttccggca gtttatgcct aagcgaacgg tgaaaacaca
    24061 ttatgaatga tgaggattgt catggctgaa ttactgttag gcgtcaacat tgaccatatt
    24121 gcaacactgc gtaacgcgcg cggtactgct tacccggatc cggtgcaggc ggcgtttatt
    24181 gctgagcagg cgggagcgga cggcattacc gtgcatttac gtgaagaccg ccgccacatt
    24241 accgaccgcg atgtgtgcat cctgcgccag acgctggata cccgcatgaa tctggagatg
    24301 gcggtgaccg aagagatgct ggcgatcgcc gttgagacga agccacattt ttgctgtctg
    24361 gtaccggaaa agcgtcagga agtaacaacc gaaggcggcc tggacgtcgc agggcagcgt
    24421 gaaaaaatgc gcgatgcctg caaacgtctg gcagatgccg ggatccaggt ttctctgttt
    24481 atcgacgccg atgaagagca gatcaaagct gcggcagagg ttggcgcacc gtttatcgag
    24541 atccacaccg gttgctatgc tgatgccaaa actgacgccg aacaggcgca agagttggcg
    24601 cgtatcgcca aagccgcgac ctttgccact agtctcggtc tgaaagttaa cgccggacac
    24661 ggtctgacct atcacaacgt gaaagccatt gccgccatcc ctgagatgca tgaactgaat
    24721 atcggtcatg ccattattgg tcgtgcagtg atgaccggac tgaaagatgc ggtggcagaa
    24781 atgaagcgtc tgatgctgga agcgcgtggc taatggcaat attaggttta ggtacggata
    24841 tcgtagagat cgctcgcata gaagcggtga tcgcccgatc cggtgagcgc ctggcacgcc
    24901 gcgtattaag cgataacgaa tgggaaatct ggaaaacgca ccaccagcca gtgcgttttc
    24961 tggcgaagcg ttttgctgtg aaagaagcgg cggcaaaagc atttggcaca gggatccgca
    25021 atggtctggc gtttaatcag tttgaagtat tcaatgatga gctcggcaaa ccacggctac
    25081 ggctatgggg tgaggcatta aaactggcgg aaaagctcgg cgttgtaaat atgcatgtaa
    25141 cgcttgccga tgagcgccac tatgcttgtg ccacggtaat tattgaaagt taaaataata
    25201 ccgttctctt tataaagtaa aacccccgaa ctggtaagga acgggggttt tactttttaa
    25261 ctttaatttt gtgcagcaca cgattccaac gaaaatgatt atggatcaat ttcgttgacc
    25321 tgtacaagca acttgcaatc tctgacataa aaaacgcgag cctttacgaa gaaatcgaca
    25381 ttgatgaaaa gattaacgtg accgcttttt gataagtaca ttaaaatcgg tttcgttatt
    25441 ggcaattttg ctgtgcttta caccatgcca ctgaattccc ccattgaaac gagtggtgtc
    25501 gtcaaagctc tggtgtggag tgcagcactc gattccaata actcgcacgt tcagttttgg
    25561 ggagatgtaa gggctaatct gaacggctgc attccttgtt taaggaaaaa cgaatgactg
    25621 attgccgata cctgattaaa cgggtcatca aaatcatcat tgctgtttta cagctgctcc
    25681 ttttgttctt ataacacaag gaaacgtact taaggtgcgt ccggtgaacc aatcggacgc
    25741 gcctttaata actataaata agtgtctggg cagata
//
LOCUS       DAFGPF010000069        24952 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFGPF010000069 DAFGPF010000000
VERSION     DAFGPF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24952
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.069"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            160..3918
                     /gene="yfaL"
                     /locus_tag="LSX49_003131"
     CDS             160..3918
                     /gene="yfaL"
                     /locus_tag="LSX49_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HBL7169510.1"
                     /translation="MRIISLRKEYLSLLPSMIASLFSANGAAAVIDSCQGYDIKASCQ
                     ASRQSLSGNIQDWSIADGQWLIFSGMVNNASGGAVFLQHSAEFTISPQNETGMTLFAD
                     NSVSGEYNNGGAIFAKENSTINLANVIFDSNVAGGYGGAIYSAGTNDTGAADLRVTNA
                     VFHNNIANDGKGGAIYTINNDVYLSDDAFNNNQAYTSTSYSDGDGGAIDVTDNSTDKT
                     HLSGKTIINNTSFTNNYAEGYGGAIYTSSTTSPYLIDISVDDNYDQNNGVMIDENNSA
                     SGYDHSATAAAGGFMYIGHSVAEFNIAADKTLVIGNTSNDGAIDSLAGTGVIVKEGAG
                     ELVLNADNNAFTGEMSIQNGEVTLGRSDELMNVGDTHCQSDPQDCFGLMVGSTVHSEY
                     QAELNVGNTQQTFVHSLTGFANGILNIDAGGNVTVNQGGFSGSIQGEGQLTVAQDGSY
                     LLTGAQSMALTGDIVVEDNAVLSLAGNQADLRAMQSDPQSIVLNGGVLDLSDFTTWDG
                     DSSYNDGLQISGSGGTVIGSNDVVDISSGDDLHIGGSDASQNGVYVVINAGDQRVTLA
                     NNNGYLGNTQIASGTLEVSDNSQLGDTSYNRSVIFTDPQQHSEMDVTTDVDTRSATTG
                     QGRNIEMRADGEIHVEDGVDTQWGGLMADSTGQQLDSVSTLTKSGGGTLELTASGTAT
                     SAVRVEDGTLKGEAENIIPYVSSLWVGEDGVFETGQNQDIRSIDATSGGDIDITDGTV
                     LRLTQQDTNQALDASLFSGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLT
                     NTSGAVSLQNGIAGDTLTVNGDYTGGGTLLLDSELNGDDSASDQLVLNGNTAGNTTVV
                     INPITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWY
                     LRSQEVNPTPPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYFNNLRAANQ
                     AFVMERRDHAGGDGQTLNLRVIGGRYHYTAAGQLAQHEDTSTVQLSGNLFSGHWGDDG
                     EWMLGIVGGYSDNQGDSRSNMTGTRADNQNRGYAVGLTSSWYQHGNQKQGAWLDSWLQ
                     YAWFNNDVSEQDDGVDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFT
                     AANHARVSQSQGDDIQMRLGLHSEWRTAVGVTPTLDLNYYHDPHATEIEEDGSTISDD
                     AVKQRGEIKVGITGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW"
     gene            complement(4058..4780)
                     /locus_tag="LSX49_003132"
     CDS             complement(4058..4780)
                     /locus_tag="LSX49_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HBL7169511.1"
                     /translation="MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNP
                     ITNTFKLGPGVDVNYMLHTQNK"
     gene            4927..7554
                     /gene="gyrA"
                     /locus_tag="LSX49_003133"
     CDS             4927..7554
                     /gene="gyrA"
                     /locus_tag="LSX49_003133"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HBL7169512.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTSEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            7703..9013
                     /locus_tag="LSX49_003134"
                     /pseudo
     CDS             7703..9013
                     /locus_tag="LSX49_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 family protein"
     gene            9018..9776
                     /locus_tag="LSX49_003135"
     CDS             9018..9776
                     /locus_tag="LSX49_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaQ family protein"
                     /protein_id="HBL7169513.1"
                     /translation="MTFVSHGETTLLTVKGKLKLQSHLDREEYVARVLDREAKSTPPE
                     AAKAMTVAIRTFLQQNADREGDCLTIPDSSATQRVSASPATTGARTMTAWTQDLIYAG
                     DPVHYHGSRATEGTLSWRHATAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPK
                     AKAWLAKKMPQWRRILQGETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDR
                     LDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            9781..10557
                     /locus_tag="LSX49_003136"
     CDS             9781..10557
                     /locus_tag="LSX49_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HBL7169514.1"
                     /translation="MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASF
                     SQTINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGAGAIRARLRLVLSWDTDNTDLDLHV
                     VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYFGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            complement(10631..11815)
                     /gene="atoB"
                     /locus_tag="LSX49_003137"
     CDS             complement(10631..11815)
                     /gene="atoB"
                     /locus_tag="LSX49_003137"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA acetyltransferase"
                     /protein_id="HBL7169515.1"
                     /translation="MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKID
                     SLHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAI
                     QAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGI
                     TAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDE
                     FPKADSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLNPLARI
                     KSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKTLGFD
                     PEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIER
                     LN"
     gene            complement(11846..13168)
                     /locus_tag="LSX49_003138"
     CDS             complement(11846..13168)
                     /locus_tag="LSX49_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00366 family protein"
                     /protein_id="HBL7169516.1"
                     /translation="MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPI
                     SMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVT
                     FFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
                     LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPK
                     LLMEEADFQKQLPKDAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNL
                     MFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFI
                     NVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVMPAAQALGADLGKSVMAIAYG
                     EQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF"
     gene            complement(13165..13815)
                     /locus_tag="LSX49_003139"
     CDS             complement(13165..13815)
                     /locus_tag="LSX49_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-CoA--3-ketoacid-CoA transferase"
                     /protein_id="HBL7169517.1"
                     /translation="MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQ
                     SENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFDSAMSFALIRGGHIDACVLGGLQ
                     VDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
                     QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL"
     gene            complement(13815..14477)
                     /gene="atoD"
                     /locus_tag="LSX49_003140"
     CDS             complement(13815..14477)
                     /gene="atoD"
                     /locus_tag="LSX49_003140"
                     /EC_number="2.8.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase subunit alpha"
                     /protein_id="HBL7169518.1"
                     /translation="MKTKLMTLQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGV
                     RDLTLIANDTAFVDTGIGPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGT
                     LIEQIRCGGAGLGGFLTPTGVGTVVEEGKQTLTLDGKTWLLERPLRADLALIRAHRCD
                     TLGNLTYHLSARNFNPLIALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQE
                     SK"
     gene            complement(14673..16058)
                     /gene="atoC"
                     /locus_tag="LSX49_003141"
     CDS             complement(14673..16058)
                     /gene="atoC"
                     /locus_tag="LSX49_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetate metabolism transcriptional
                     regulator AtoC"
                     /protein_id="HBL7169519.1"
                     /translation="MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLF
                     ADIHPDVVLMDIRMPEMDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDY
                     VIKPFDLDELNLIVQRALQLQSMKKEIRHLHQALSTSWQWGHILTNSPAMMDICKDTA
                     KIALSQASVLISGESGTGKELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHE
                     KGAFTGAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIK
                     VDIRVIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDISLLANHFLQKF
                     SSENQRDIIDIDPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQ
                     PVCNAGEAKTAPVGERNLKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYK
                     LQEYGIDPADV"
     gene            complement(16055..17881)
                     /gene="atoS"
                     /locus_tag="LSX49_003142"
     CDS             complement(16055..17881)
                     /gene="atoS"
                     /locus_tag="LSX49_003142"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     AtoS"
                     /protein_id="HBL7169520.1"
                     /translation="MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVL
                     SEKEKKLSAVVNLLNQALGNRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAG
                     YYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMI
                     PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANI
                     DIITDGLSTLAQNIPTRLPQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVI
                     AIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALE
                     ISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGEL
                     MAGVAHEVRNPLTAIRGYVQILRQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRP
                     RHSQWQQVSLNALVEETLVLVQTAGVQARVDFISELDNELSPINADRELLKQVLLNIL
                     INAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPFFTTKASGTGL
                     GLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV"
     gene            18048..20897
                     /gene="rcsC"
                     /locus_tag="LSX49_003143"
     CDS             18048..20897
                     /gene="rcsC"
                     /locus_tag="LSX49_003143"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HBL7169521.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQTDVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVNKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLNKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRES"
     gene            complement(21097..21747)
                     /gene="rcsB"
                     /locus_tag="LSX49_003144"
     CDS             complement(21097..21747)
                     /gene="rcsB"
                     /locus_tag="LSX49_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HBL7169522.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(21764..24436)
                     /gene="rcsD"
                     /locus_tag="LSX49_003145"
     CDS             complement(21764..24436)
                     /gene="rcsD"
                     /locus_tag="LSX49_003145"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HBL7169523.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDTWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGNNENEKEGTDSVSIHFNS
                     TKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTESVPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMTFMKNIGDALKEPAQSLAESAAKLNAPEGKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETELFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPE
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
BASE COUNT         6172 a         6028 c         6607 g         6145 t
ORIGIN      
        1 cttaaagtta ttaatctgaa ttgtgatgca tctaaattaa tcatcaaata ataacaaagt
       61 ggttattaca tcgggggcag aatttacaaa agaaaaatac cctatatcgc ataatgcgat
      121 taaatacgcc atcttataga aaatgatggt tagatgaata tgcggattat ctctctacgc
      181 aaggagtatt tatctttact cccgtcaatg attgcatctc ttttctctgc taacggtgcc
      241 gcagcggtca ttgattcatg ccagggatat gatatcaaag cgagctgtca ggccagcagg
      301 caaagccttt cgggtaatat acaggactgg agcatcgcgg atggacaatg gttgattttt
      361 tcgggtatgg tcaataatgc cagcggtggc gcagtatttt tgcagcacag tgctgaattt
      421 acgatatcac cacaaaatga aacagggatg accctgtttg ctgataactc ggttagtggc
      481 gaatataata atggcggggc tatctttgct aaagaaaact caacgataaa tcttgcgaat
      541 gttattttcg acagtaatgt tgcaggaggc tatggcggag caatctattc tgccggtacc
      601 aatgataccg gtgccgccga tttacgagtc actaacgccg tatttcacaa taacatcgct
      661 aatgacggca aaggcggtgc aatttatacc atcaataatg acgtctattt aagtgatgat
      721 gcttttaata ataaccaggc atatacatca acaagttata gtgatgggga tggcggcgcc
      781 attgatgtta cggataatag tacggataag acacatcttt caggaaaaac gataattaat
      841 aatacctcct ttaccaataa ctatgcagaa ggttatggcg gagcaattta taccagcagc
      901 accacatccc cgtatcttat tgatatttct gttgatgata attatgacca aaacaatggt
      961 gtgatgattg atgaaaataa cagcgcctcg ggatatgacc attcggcgac ggcagcggcg
     1021 gggggcttta tgtatatcgg tcatagtgtg gctgaattta acattgccgc cgataaaacg
     1081 ctggtaatag gcaataccag caacgatggc gcgattgatt ctcttgccgg aacgggagtc
     1141 atcgtgaaag agggagcggg agagttagtc ctcaatgccg acaataatgc gtttaccggc
     1201 gagatgagta tccagaatgg cgaggtgacg ttggggcgca gcgatgagtt aatgaatgtc
     1261 ggcgacacgc actgtcagag cgatccgcag gattgctttg gtctgatggt cggcagcact
     1321 gttcattctg agtatcaggc agaactgaat gttggcaata cacaacaaac gtttgtgcac
     1381 tcattaaccg gttttgctaa tggcattttg aatatcgacg caggcggcaa tgttaccgta
     1441 aaccagggcg gtttttccgg ctcgattcag ggtgaaggac agttgacggt agcgcaagat
     1501 ggcagctatc tcctgacagg ggcgcagtcg atggcattaa ccggcgatat tgtggtggaa
     1561 gataacgccg tattgtcgct ggcggggaat caggccgatt tacgggcaat gcagagcgat
     1621 ccgcaatcga tcgtgctaaa tggcggagta ttggatctct ctgatttcac cacctgggat
     1681 ggcgatagct catacaatga cggtctgcaa atcagcggca gcggggggac agtgattggc
     1741 agtaatgatg tcgttgatat cagcagtggc gatgatttac atattggcgg cagtgatgcc
     1801 agccagaatg gcgtttatgt cgtcattaat gcgggggatc agcgcgtaac gctggcgaat
     1861 aacaacggtt atctcggtaa tacgcaaatc gcctccggta cgcttgaagt cagcgataat
     1921 tcgcaattgg gggacacaag ttacaaccgt tcagtgatct tcacagatcc ccaacaacac
     1981 agtgaaatgg atgtgacgac tgatgttgac actcgctcgg ctacaacagg tcagggcagg
     2041 aatattgaaa tgcgcgctga tggcgaaata cacgttgagg atggcgtaga tacgcaatgg
     2101 ggcgggttga tggcggatag taccgggcaa caactggata gcgtaagcac gttgactaaa
     2161 agtggcggcg ggacgctgga gttgaccgcc agcggcactg cgacgtctgc ggtacgtgtg
     2221 gaagacggaa cgctaaaagg tgaagcggag aatattattc cttatgtttc ttcactgtgg
     2281 gtgggggaag acggtgtttt tgaaaccggg caaaatcagg atattcgctc aatcgatgcc
     2341 acctctggcg gcgatatcga cataaccgat ggtactgtgt tgcgattgac gcagcaggat
     2401 acgaaccagg cgctggatgc ctcgctgttt agcggcgacg gtacgctggt gaatgccacc
     2461 gatggcgtga cgttgacagg tgagcttaat accaaccttg aaactgacag cctgacttat
     2521 ctttccgacg tgacggttaa tggcaatctg accaatacgt ccggtgctgt cagtctgcaa
     2581 aatggcatcg ctggcgacac gctgacggta aatggtgatt ataccggcgg cggtacgcta
     2641 ctgctcgaca gcgaattaaa cggcgatgac tcggcaagcg accagttggt gttgaacggt
     2701 aatactgctg gcaataccac ggttgtgatt aatcccatta cagggattgg tgagccgaca
     2761 tctacaggta ttaaagtggt tgatttcgca gctgatccca cgcagtttca aaacaatgcg
     2821 cagttcagtc tggcaggaag cggctacgtc aatatggggg cgtatgacta cacgctggtg
     2881 gaagataaca acgactggta tctgcgatca caagaagtca atccgacgcc gccgcctgat
     2941 ccagacccga ctccagatcc tgatcccacg ccggatcccg acccaacccc cgaccctgaa
     3001 cctacgcctg cttaccagcc ggtgttgaat gccaaagttg gtggatattt taataaccta
     3061 cgtgcggcaa atcaggcatt tgtgatggag cgacgcgatc acgcaggtgg cgatggtcag
     3121 acgctgaatt tacgcgttat cggcgggcgt tatcattaca cggcggcagg gcagttggct
     3181 cagcatgaag acacttctac ggtgcagctt agcggcaacc tgtttagcgg gcactggggt
     3241 gatgatggcg agtggatgct tgggattgtt ggtggctaca gcgataacca gggcgacagc
     3301 cgctcgaata tgaccggaac tcgcgccgat aaccagaacc gcggttatgc cgttgggctg
     3361 acctcaagct ggtatcagca cggtaatcag aagcaggggg cctggttgga tagctggctg
     3421 caatatgcgt ggtttaacaa tgatgtttcc gaacaagacg atggagtgga tcattaccac
     3481 tcgtcgggga ttatcgcctc gctggaagcc ggttatcagt ggttaccggg gcgtggtgtg
     3541 gtgattgaac cgcaggcgca ggtgatttat cagggcgtgc agcaggatga ttttaccgcc
     3601 gctaaccatg cgcgcgtgtc acaatcgcag ggtgatgata ttcagatgcg gttgggttta
     3661 cacagcgaat ggcgtactgc tgttggtgtc acgccaacgt tagatctgaa ttattatcac
     3721 gatccccatg cgacggaaat tgaagaggat ggcagcacta tcagtgacga tgcggtgaag
     3781 caacggggtg aaataaaagt gggaataacg ggcaatatca gtcagcgagt ttcgctgcgc
     3841 ggcagcgtgg cgtggcagaa agggagtgat gattttgccc agatggcagg gtttttgtcg
     3901 atgacagtga aatggtaatc gctgtctgac cggcactgtt gccggatgcg gcgtaaacgc
     3961 cttatctggc ctacggggag catttgtagg cctgataaga cgcggcaagc gtcgcatcag
     4021 gcttggcgcg gttgccggat gaatccaaac aacaacctca cttattctgc gtatgcagca
     4081 tatagttcac atccacgccg gggccgagct taaaggtgtt agtgataggg ttgtaatgca
     4141 gcccggtcat atgccgttct ttaagactgg tctgatccac ccagcccagc aattctgccg
     4201 gtttaataaa cttcttcaca tcatgtgtac ctttaggcac catgcgcaaa atatattcag
     4261 caccaaccac cgccatcagc catgacttgc cgttgcggtt aagcgtcgag aaaaagacat
     4321 cgccgcccgg tttcaccagt tgcgcacagg ctctgaccac tgactgagga tcggggacgt
     4381 gctccagcat ctccatacag gtcaccacgt catactgtcc ggcatgtttt gccgcgtgct
     4441 cttccacggt ttcctgcacg taatccacct gaatgccgct ttccagtgcg tgcagttttg
     4501 ccacctgcaa tggctcaaag cccatatcca gaccggtcac cgtcgcgccc tcccgcgcca
     4561 tactctcggc cagaatgccg ccgccacaac cgacatcgag cacctttttg ccaaataaac
     4621 cgccagcacg ctcggcaata tagcccagac gcagcgggtt aatgcggtgc agcggtttga
     4681 actcaccttc aagatcccac cagcgggagg cgacggcttc aaatttagcg atctcttcgt
     4741 ggtctacgtt gtggtttacc ggcgattttt cggcattcat tggcacttct actccgtaat
     4801 tggcaagaca aacgagtata tcaggcattg gatgtgaata aagcgtatag gtttacctca
     4861 aactgcgcgg ctgtgttata atttgcgacc tttgaatccg ggatacagta gagggatagc
     4921 ggttagatga gcgaccttgc gagagaaatt acaccggtca acattgagga agagctgaag
     4981 agctcctatc tggattatgc gatgtcggtc attgttggcc gtgcgctgcc agatgtccga
     5041 gatggcctga agccggtaca ccgtcgcgta ctttacgcca tgaacgtact aggcaatgac
     5101 tggaacaaag cctataaaaa atctgcccgt gtcgttggtg acgtaatcgg taaataccat
     5161 ccccatggtg acttggcggt ttataacacg atcgtccgta tggcgcagcc attctcgctg
     5221 cgttacatgc tggtagacgg tcagggtaac ttcggttcca tcgacggcga ctctgcggcg
     5281 gcaatgcgtt atacggaaat ccgtctggcg aaaattgccc atgaactgat ggccgatctc
     5341 gaaaaagaga cggtcgattt cgttgataac tatgacggca cggaaaaaat tccggacgtc
     5401 atgccaacca aaattcctaa cctgctggtg aacggttctt ccggtatcgc cgtaggtatg
     5461 gcaaccaaca ttccgccgca caacctgacg gaagtcatca acggttgtct ggcgtatatc
     5521 gatgatgaag acatcagcat tgaagggctg atggaacaca tcccggggcc ggacttcccg
     5581 acggcggcaa tcattaacgg tcgtcgcggt attgaagaag cttaccgtac cggtcgcggc
     5641 aaggtatata tccgtgcccg tgccgaagta gaagttgacg ccaaaaccgg acgtgaaacc
     5701 attatcgtcc acgaaattcc gtatcaggtg aacaaagcgc gcctgatcga aaaaattgcg
     5761 gaactggtaa aagaaaaacg cgtggaaggc atcagcgcgc tgcgtgacga gtctgacaaa
     5821 gacggtatgc gcatcgtgat tgaagtcaaa cgcgatgcgg tcggtgaagt ggtgctcaac
     5881 aacctctact cccagaccca gttgcaggtt tctttcggta ttaacatggt ggcattgcac
     5941 catggtcagc cgaagatcat gaacctgaaa gacatcatcg cggcgtttgt tcgtcaccgc
     6001 cgtgaagtgg tgacccgtcg taccattttc gaactgcgta aagctcgcga tcgtgctcat
     6061 attcttgaag cattagccgt ggcgctggcg aacatcgacc cgatcatcga actgatccgt
     6121 catgcgccga cgcctgcaga agcgaaaact gcgctggttg ctaatccgtg gcagctgggc
     6181 aacgttgctg cgatgctgga acgtgcgggc gatgatgctg cgcgtccgga atggctggag
     6241 ccagagttcg gcgtgcgtga tggtctgtac tacctgaccg aacagcaagc tcaggcgatt
     6301 ctggatctgc gtttgcagaa actgaccggc cttgagcacg aaaaactgct cgacgaatac
     6361 aaagagctgc tggatcagat tgcggagctg ttgcgtattc tgggtagcgc cgatcgtctg
     6421 atggaagtga tccgtgaaga gctggagctg gttcgtgaac agttcggtga caaacgtcgt
     6481 accgaaatca ccgctaacag cgccgacatc aacctggaag atctgatcac acaggaagat
     6541 gtggtggtca cgctttctca ccagggttac gtgaagtatc agccgctttc tgaatacgaa
     6601 gcgcagcgtc gtggcgggaa aggtaaatct gccgcacgta ttaaagaaga agactttatt
     6661 gaccgactgc tggtggcgaa cacccacgac catattctgt gcttctccag ccgtggccgc
     6721 gtctattcga tgaaggtcta ccagttgcca gaagctactc gtggcgcacg tggtcgtccg
     6781 atcgtcaacc tgctgccgct ggaacaggac gaacgtatca ccgcgatcct gccggtgacc
     6841 gagtttgaag aaggcgtgaa agtcttcatg gcgaccgcta acggtactgt gaagaaaacc
     6901 gtcctcaccg agttcaaccg tctgcgtacc gccggtaaag tggcgatcaa actggttgac
     6961 ggcgatgagc tgatcggcgt tgacctgacc agcggcgaag acgaagtaat gctgttctcc
     7021 gctgaaggta aagtggtgcg ctttaaagag tcttctgtcc gtgcgatggg ctgcaacacc
     7081 accggtgttc gtggtattcg tttaggcgaa ggcgataaag tcgtctctct gatcgtgcct
     7141 cgtggcgatg gcgcaatcct caccgcaacg cagaacggtt atggtaaacg taccgcagtg
     7201 gcggaatacc caaccaagtc gcgtgcgacg aaaggggtta tctccatcaa ggttaccgaa
     7261 cgtaacggtt tagtggttgg cgcggtgcag gtagatgatt gcgaccagat catgatgatc
     7321 accgacgccg gtacgctggt acgtactcgc gtgtcggaaa tcagcatcgt aggccgtaac
     7381 acccagggcg taatccttat ccgtacttcg gaagatgaaa acgtggtggg tctgcaacgt
     7441 gttgctgaac cggttgacga ggaagatctg gataccatcg acggcagtgc cgcggaaggg
     7501 gacgatgaaa tcgctccgga agtggacgtt gacgacgagc cagaagaaga ataatttcat
     7561 cgcttcatgc caaaagggag ccatctccct tttttgaatt gaaaagtcca ggctgtaaag
     7621 tctgggcttt tgtcgtatta gggcgcggta aagtttggct gtgcccgtaa aaaatggctg
     7681 gctatacaca aggaatgtgg caatgagtgg tgaaaaaaag gcgaaaggct ggcggtttta
     7741 tggccttgtt ggttttgggg caatagcgct gctatccgct ggcgtatggg cattacaata
     7801 ctctggcagt gggccagaaa aaacgttgtc gccactggtg gtgcacaaca atctgcaaat
     7861 cgatctcaat gagccggacc tctttctcga cagcgactct ctgagccagc ttcccaaaga
     7921 tctccttacc attccgtttc tccacgatgt tctgagcgaa gatttcgttt tctattatca
     7981 gaatcatgcc gatcgtctgg gcattgaagg cagcattcgc cgcattgtct atgaacacga
     8041 tctcacgctg aaagataagc tcttttcgtc actcttagac cagcccgcgc aggcggcact
     8101 gtggcacgat aaacaaggcc atctttctca ttatatggtg ctgatccagc gaagtggttt
     8161 aagcaagctg ctggagccat tgctgtttgc cgctaccagc gacagccagt taagtaaaac
     8221 ggaaatcagt agcatcaaga taaatagtga aactattcct gtttatcagt tgcgctataa
     8281 cggcaataac gtcctgatgt ttgcgactta tcaggacaaa atattggctt tttccagttc
     8341 ggatatgctg tttaaagatg accaacagga taccgaagcc acggcgatcg caagtgattt
     8401 gttgagtggt aaaaaacgct gggaaacccg ctttggcctg gaagcgcgta ctgccgaaaa
     8461 aacgccagta cgccagcgca tcgtagtcag cgccaggttg ctggggtttg gctaccagcg
     8521 attaatgcct tcttttgctg gcgtacgctt cgaaatgggt aacgacggct ggcacagttt
     8581 tctggcgtta aacgatgaat ccgccagcgt agatgccagt ttcgatttta cgccggtatg
     8641 gaacagtatg cctgccggag ccagcttctg tgtggcggtg ccgtattcac acggtattgc
     8701 cgaagagatg ctttcgcaca tcagccagga aaacgacaag ctgaatgggg cgttagacgg
     8761 tggcgcgggg ctgtgctggt atgaagactc aaaattgcaa accccactgt ttgttggtca
     8821 gtttgatggc actgccgaac aggcgcaatt gccagggaaa ctgtttacgc aaaatattgg
     8881 tgcgcacgaa agcaaagcgc cagaaggtgt tttgccggta agccagactc agcagggcga
     8941 agcgcaaatc tggcgtcgcg aagtgagttc ccgatacggt cagtatccga aagcgcaggc
     9001 ggcgcaaccc gatccacatg acatttgtca gccacggtga gacaacgtta ctgacggtaa
     9061 agggcaaact gaaattacag tcgcatctcg atcgtgaaga gtacgttgcc agagttctgg
     9121 atcgcgaggc gaaaagtacg cctcctgagg cagcgaaagc catgaccgtg gcgattcgca
     9181 cgtttttaca gcaaaacgcc gatcgggaag gcgattgcct gaccatcccg gacagcagcg
     9241 ctacgcagcg tgtttctgct tcgccagcta ccacgggggc gcgaacgatg accgcctgga
     9301 cgcaggatct catctatgcg ggcgatccgg ttcattatca tggcagtcgc gctaccgaag
     9361 ggacgctttc ctggcggcac gctactgccc aggcggggca gggagagcgt tatgatcaga
     9421 tactcgcgtt tgcttatccc gacaacagcc ttagccgctg gggagcgcca cgctcaacct
     9481 gccagttatt acccaaagcg aaagcctggc tggcgaaaaa aatgccgcag tggcggcgta
     9541 tattacaagg tgagacggga tacaacgaac cagacgtgtt tgcggtctgt cgtttagtct
     9601 caggtttccc ctataccgat cggcagcaga aacggctgtt tattcgtaat ttctttacgc
     9661 ttcaggatcg gctggattta acccatgagt atctgcacct ggcctttgat ggttatccca
     9721 ccgggcttga tgagaactat atcgaaacgc tgacccgaca attattaatg gactaatgct
     9781 atgcgaaaga tttttcttcc gttgttactg gtggcgcttt cgcctgtcgc tcacagtgaa
     9841 ggtgtgcagg aagtcgagat tgatgcaccg ctctctggct ggcatccggc agagggcgaa
     9901 gatgccagtt tttcacaaac gatcaattac ccggcgtcgt ccgtcaacat ggcagatgat
     9961 caaaatatct cagcgcagat ccgcggcaaa ataaagaatt atgctgcggc gggtaaagtt
    10021 cagcagggcc ggctggtggt caacggtgcc agtatgccgc agagaattga atcagatggt
    10081 tcttttgcac gcccttatat tttcactgaa ggcagcaaca gcgtgcaggt catcagccca
    10141 gatgggcaaa gccgacaaaa aatgcagttt tactcaacgc cgggtgctgg ggcgattcgc
    10201 gcgcgtttac ggctggttct ctcctgggat acggacaata ccgacctcga tcttcatgtc
    10261 gttacgcctg acggtgaaca tgcctggtac ggtaacacag tgctgaaaaa cagtggcgca
    10321 ctggatatgg atgtcacgac agggtacgga cccgagattt tcgccatgcc agcgccagtt
    10381 cacggccgtt atcaggtgta tatcaactac ttcggcgggc gcagtgaaac ggaattaact
    10441 acggcccaac tgacgctgat caccgatgaa gggtcggtca atgagaaaca ggaaactttt
    10501 attgtaccga tgcgtaatgc tggcgagctg acgctggtga aaagttttga ctggtgatta
    10561 atggggtaac cttcgccgtc gatgttcaag aaaacgcccg ataactttcg ctatcgggcg
    10621 tttttattgg ttaattcaac cgctcaatca ccatcgcaat tccctggccg ccaccaatgc
    10681 atagtgttgc cagccccagc gttttatcgc gtgcctgcat tgcatgtaat agtgtgacca
    10741 gaatacgagc accactggca ccgataggat gtccgagcgc gatggccccg ccgttgacat
    10801 tcactttctc aggatcaaag cccagggttt tcccaacggc aaggaactgt gcagcaaatg
    10861 cttcattagc ctcaatgaga tcaatatccg ccagttgcag ccccgccagt tgtaacgctt
    10921 tttgcgtagc aggtactggc cccataccca tcaatgcggg gggcacgcca ccgctggcat
    10981 aacttttaat gcgtgccagg ggattcaggc ctgctgccag cgccgcagat tcttccataa
    11041 tcaccagagc ggcagcaccg tcgttaatac ctgacgcgtt cccggcggtg actgttcctg
    11101 ctttatcgaa ggccgggcgc aatgcgccta acgcttcagc cgtagaatcc gctttcggga
    11161 attcgtcttg actgaagacg aaggttttct tccgggtgac aacatttacc gggacgattt
    11221 cggctgtaaa agcaccggac tcaattgcgg ctgccgcttt acgctgtgaa tgtagcgcca
    11281 gttcatcctg catttcacgg gtaattccgt actctttagc cacgttttcg gcggtaatcc
    11341 ccatatgata accatgggtg gcgcacatca ggccatcgcg caggattacg tcataaacct
    11401 gtccgtctcc aagacgataa ccagagcgtg cttttgcatc gagtaagtag ggcgctaaac
    11461 tcatattttc catacccccc gccacaatgc tctgtgcctg acctgcctga atcgcctgtg
    11521 cagcaagcgc cacgcttttc agacctgaac cgcacacttt gttgaccgtg aatccgcaca
    11581 ccgtttcagc tagtccgctt tttagcagcg cctgacgtgc cggattttgc cccagtccgg
    11641 cttgcaacac gttacccata atcacttcat caacgtgtag tgaatcgatt tttgcacgtt
    11701 caatggcggc tttaattact gtcgccccca ggtcgatggc gctggtggaa gcgagtgaac
    11761 cgttaaaact accgatagca gtacgtaccg cactgacgat gacacaattt ttcattttat
    11821 attccttctg tctgtagggt tgccgtcaga acagcgttaa accaatgacg aaaatgacgc
    11881 cggagaagag cagggcagtg atgcaatagc ccatgatgtc gcggacaccg agtccggcga
    11941 ttgccagtgc tggcagcgcc cagaacggtt gtgccatgtt catccattgc tcgccgtagg
    12001 cgatcgccat taccgattta ccgagatcag cgcccagcgc ctgggctgcg ggcatcacga
    12061 acggcccctg aataacccag tgcccgccgc cagacggaac ggcgaagtta atcagtgcag
    12121 aactaaaaaa ggtcatgacc gggaaggtgt ctttgttcgc aacattgatg aagaattcgg
    12181 taatgagtcc gcccagaccg gagtgctcca tcatcagttg gatccccgcg tagaagggga
    12241 attgcaccag aataccggcg gtactgcgtg ctgccgcgct gatagcacgc atataagcca
    12301 ttggcgtttt atgtagcagc agacccgcaa tcataaacat caggttgacg gtattgatgg
    12361 tgatgttgaa gccatgttcg ctgaagtaca tcgccaggta agcgataccg agtgcgccga
    12421 tgatcaacgt cagaatgcgg ctttcttcca gtcgctcgga cggtggagca tctttcggta
    12481 gttgcttttg aaaatcagcc tcttccatga gtagtttcgg atcgatactc accacgtcag
    12541 acggttttgg catcatcatg cgggtgataa atggcatcac cacaatcaac gccacagtga
    12601 tgaaaatatt aaaaccactg aacagagtat cgcccaccgg gatcagccca gcgatatgct
    12661 caaccgggtt gcccggtgtt gcagccaaca gaggcattga gccagagaag ccgccacccc
    12721 aggtgagaaa accaatgtag gcgcaggcaa tgagcaacgg ataatcagaa ccgggtactc
    12781 gccgggcgac ttcacgggcg aacattgcac cgacaaccaa accaaatccc cagttgatga
    12841 cacaagcgac tgaaccgaag aaagtaacca gcatgacgcc ctgtacgggc gtctttgcgg
    12901 cggaggcggc agtacgcagc aaacttttca ccggagcgga gctggcaagg gcatgaccgg
    12961 taacgatgat aagcgccatc tgcataccaa acgccagcaa gttccagaaa ccgtcacccc
    13021 acattttcac catgctgatc ggcgtttgtg gtgttaacca aagcgcgatc acgaatgtta
    13081 gcaatgtcag caacatggca aagatcagtg gatcgggaag ccaccggctg acaaaacgcg
    13141 tcataaaacg cgatatgcga ccaatcataa atcaccccgt tgcgtattca gatcggcagc
    13201 tacttcaaac cgagcttctg ttttggcacg cacggtggct aaatcacacc cgtcggcaat
    13261 ttcggtgagc cacattttgc cgtcaataaa acgaaagaca gccagttcag taaccagcat
    13321 atgcaccgca tgttgcgcag tgagtggcat ggtgcagcgg cgcaaaattt ttgctgaacc
    13381 atctttggcg caatgttcca tggcgatgat cactttgcgt gacccggtca ccagatccat
    13441 cgcgccaccc ataccgggca ccattttccc aggcactacc cagttcgcga ggtttgcttc
    13501 ttcgtctact tgcaaaccgc cgagcacgca ggcatcaata tgaccgccac ggattagcgc
    13561 aaatgacatg gcgctatcaa acatggctgc accgggtaaa atgccgcacg gttgtccgcc
    13621 agcattcacc agatctggat gcgctgttgt gaccgggcct aaaccgagga agccgttttc
    13681 cgattgcaga gtgatatgaa taccctccgg taaataattg gcgaccattg tgggtaaacc
    13741 gatccctaag ttaacgatgt caccatcacg aagctcttgc gccacacggc gcgcaatacg
    13801 ttgtttcgca tccattattt gctctcctgt gaaacgatga tgtggtcgat aacggcacca
    13861 ggggtgacaa tatggtcagg ttgcagctcg ccggtttcga ccagttcatc cggctctacc
    13921 agcgtgatat cagccgcaag ggctatcagg gggttaaagt tgcgggcgct aaggtgatag
    13981 gtcaggttgc caagtgtgtc gcaacgatga gcgcgaatta gcgccaggtc ggcgcgcagc
    14041 gggcgttcga gcagccaggt tttaccgtcg agtgtcagtg tctgtttgcc ttcctctacg
    14101 acggtgccga caccagttgg ggtgagaaaa ccaccaagtc cagctccgcc acagcgaatt
    14161 tgctcgatta gcgtaccttg cggcaccaga acgacgtcca tctcaccaga tatcatgcgc
    14221 cgacctgttt ccgggttggt gccgatatgt gaagcaatca ctttgcggac tcgaccattg
    14281 acgatgagcg gaccgatgcc ggtatcaaca aacgcggtat cattggctat caatgtcagg
    14341 tcgcgaacac cagattccag taatgcttca accaggcggg atggagtgcc aatccccata
    14401 aatccgccca ccatgatggt catgccgtca cgaaagaagc cggtggcgtc ttgtaatgtc
    14461 atcaattttg ttttcatttt ttatccctct tgcatacacc gttgtgggta cagtcaggga
    14521 atagcaaggg gagtgccaga atgagattat tgaatgttgt tatttaacta attgaataga
    14581 aaaggataaa ttagatgggg gttcataagg agaatgagcg gctatgcaga aaattgcgca
    14641 ctgtgcaaat ttctgcatag caagttttgg cattatacat ccgccggatc gataccgtat
    14701 tcctggagtt tatacatcaa tgcacggcga ctgatgccca gcattaaagc agtgcgggtt
    14761 cggtttcctt cttgttgttc cagcacttcc ataatgatgc gtttttcgac gcgtttaatt
    14821 tcctctttta aattacgctc accgacaggg gctgtttttg cttcaccagc attacagact
    14881 ggctgacgaa tctgcggcgg aagatcctca gaaaaaatga tcgggcctga attcatcacg
    14941 acggcgcgtt caataacgtt ggaaagctct cgaatatttc ccggccatga ccaggcggta
    15001 agcagtgaca ttgccatcgg atcgatgtcg ataatatcgc gctgattctc actactgaat
    15061 ttttgcaaaa agtgattagc taacagggaa atatcttccc ggcgatcgcg cagaggcggc
    15121 agtattaaat gaataacgtt aaggcgataa aagagatctt cacggaaggt gccttctttc
    15181 accattgcct gcaagtcgcg gttggtggca gcaatgacgc ggatatcaac ttttatggtc
    15241 tgatggccgc caatccgttc aaattcccgt tcctgcagaa tgcgtagtaa tttggcttgc
    15301 agtaccagcg gcatttcgcc aatttcgtcg aggagcagag taccttcgtt ggcacgttca
    15361 aataatccct gacgcaaggt ttgtgcacca gtaaatgcac ctttttcatg accaaacagt
    15421 tcactttcga gcaacgattc cggcagtgcc gcgcagttga ctttaatgaa cggccccttt
    15481 gcccgccgcg aattgtagtg aatcgctctg gcaatcaact ctttcccggt gccgctttca
    15541 ccgctaatca agacgctggc ctgagaaagg gcaattttgg cggtgtcttt gcagatgtcc
    15601 atcatcgccg ggctgttggt gagaatgtgc ccccattgcc agctggtgct cagtgcctgg
    15661 tgcagatgac ggatctcttt tttcattgac tggagttgta aagcgcgctg aacgattaaa
    15721 ttcaactcat cgagatcaaa cggtttgata acatagtcga aggctccgca gcgtagtgct
    15781 tcgacggcgg tttccacttc agcataggcc gtcatcagaa taacgggtgt ccgggtctca
    15841 tggctgcgca tctcctttag tgccttgatg ccgtccatct ctggcatgcg gatatccatc
    15901 aacaccacgt cagggtgaat atcggcaaac aggtgtaatg ctgtgcgccc gttgttcgca
    15961 caatgtgttt cgaatccttg tagtgcaaaa gcggtgctca gcatacggcg aacattatct
    16021 tcatcatcca caataaggat gcgattaata gcagtcatac agtctgattt ccctgcgggt
    16081 tgatcggtaa aataagcgtg aaggttgcgc cgtagcccgg caaactggcg acgcgaatat
    16141 caccctgatg ggcattaatg atgcgttgac ttaacgccag accaagcccg gttcctgagg
    16201 ctttggtagt gaaaaaggga tcgaagatct ttttttgcag cgagagatca atgccactgc
    16261 cgttgtcctc tatcgaaatg gcctgttgcg agtcgctata ctgccaggtt cgaatgcgaa
    16321 ttttccctcg tgcactgata gcctggacgg cattgatcag gatattcagt agtacctgtt
    16381 tgagcagttc acgatcggcg ttaatcgggc ttaattcatt atccagttcg cttatgaagt
    16441 cgacccgcgc ttgtacgccg gcggtttgta ccagtaccag agtttcttca accaatgcat
    16501 tgaggctgac ttgttgccat tgactgtggc gtgggcgtga aaattcgagc aattgctgaa
    16561 taactttgtt aattgaatcg atttctttga gtactacgga cagatattcc tgatgtattg
    16621 ggtcacgggt ttgttggcgc aagatctgta cataaccacg aatagccgtt agcggattac
    16681 gtacttcatg cgccacgcca gccatcagct cacccagtgt ggcgaggcgt tctgcttgcg
    16741 ccatgcggcg ctgggtttct ttgcgggcag ttaaatcaga gaaaatcacc aaagcaccta
    16801 tcatttcacc gtgcgtgtta tgaatacgac tggtcgtgac actgagttca atggtgcggt
    16861 cacggcctgg aaaactgatc tccagtgcaa catgttcggt gccatgttcc agcgtatcca
    16921 gtacgggact gtagaactga gtattgtcga acaacatgga gtaaggctgc cctaccagtt
    16981 catgacgttg atagccagtg atgacttctg ctgctgggtt catggtggtt acatcaccct
    17041 ggcggtcaat ggcaatgacg ccatcggcag cgttttcaat aatcagatcg ttaagtgttc
    17101 gcgtttcacg cagtgcctgg gcgaggttgt taacactctg actgatttgc cccatttcac
    17161 cgggcaattg tggtaatcga gtgggaatat tttgagccag agtcgagagg ccatcggtga
    17221 tgatatctat attggcgctc aggcgacggg agaaaaggac aatcaacagc aggcttatca
    17281 gcaaaccggc ggtgagcaca atgataatcc tcacatccat tttccaggcc tggcggcgaa
    17341 tatcttcggt taattcattg gcccagatat agccgaggat ttcaccatta cgctcaatgg
    17401 gaatcattga attcaaaata tcgccgcgca cctgcctgcc tgaataaacc aaaggggtat
    17461 ttgtacgcat gacttcgcga ccagggtgat ctgcggcaat ggtaacgccc acattattct
    17521 gatatagcgc tgaaggcgcg taggtgatta tcgcatccag cgttttgttg taataaccag
    17581 cgccgatgcc agggaaggcg tgagtgatat tttcggtaat gggggcaagt tctgcattta
    17641 atgcgcggat acgctcctca cgcggtaagt cgatgtagag atcgtagcga ttgcctagcg
    17701 cctgattaag caggttgacc acggcagaaa gttttttctc tttttcagat aagactgctg
    17761 aacgtccttc cgtttctacg atataaccaa tagtaagcgt tgggacaatg accatcagga
    17821 ttgccatcag gatcatttga ttgcgtaagc ggcgtggata aatccacttc atataatgca
    17881 tgctgaaatc cactagtctt gtccggtata tgacgattat cagaggttaa ggtgatgatt
    17941 tctcggcggt gtatcatatt ccagagaaga gagaacattg cggtaacacg cttttaccgc
    18001 taccttaacc acactccatc ggtcacctga ggcggagctt cgcccctttg aaataccttg
    18061 cttcttttcg tacaaccctg aaagcctcgc gctacatgtt cagagcattg gcgttagtgc
    18121 tctggctgtt gattgctttt tcatccgttt tttacatcgt taatgcgtta catcagcgag
    18181 aatcggaaat tcgtcaggaa tttaatctga gttccgatca ggctcagcgc tttattcaac
    18241 gcacctctga tgtgatgaaa gagctgaagt acatagctga aaatcgctta tcggcagaaa
    18301 acggtgtgct ttccccgcgt ggacgagaaa cgcagacgga tgtgcctgcg tttgaaccgc
    18361 tgtttgctga ctctgattgt tccgcaatga gtaacacctg gcgaggttct ctggagtcat
    18421 tggcgtggtt tatgcgctac tggcgcgata atttttctgc ggcttacgat ctaaaccggg
    18481 tatttttaat cggcagcgat aacctctgca tggccaattt cggtctgcgt gatatgccag
    18541 tggaacgcga taccgcgcta aaagctttgc atgaacgcat taataaatat cgaaatgcac
    18601 cacaagatga tagtggcagt aacctctact ggatcagcga aggtccgcgc cctggcgtcg
    18661 ggtattttta cgccttgacg ccagtttatc tggcgaaccg gttgcaggcg cttttgggtg
    18721 tcgagcaaac catccggatg gagaactttt tcttacctgg tacgttgccg atgggggtta
    18781 ccattcttga tgaaaatggt cataccctga tttcgcttac cggaccagaa agcaaaatta
    18841 agggcgatcc tcgctggatg caggaacgct cctggtttgg ctatacggaa gggttccggg
    18901 aactggtgct gaagaaaaat ctgccaccct catcgctaag catcgtttat tcagtgccag
    18961 ttgataaggt gctggaacgc attcgcatgt tgatccttaa cgcaattttg ctgaatgtgc
    19021 ttgccggagc tgcattgttt actctcgcgc ggatgtacga gcggcgtatt ttcattccgg
    19081 cggaaagcga cgccctgcga ctggaagaac atgagcagtt taatcgcaag attgtcgcct
    19141 ccgcgccagt gggtatctgc attttgcgta ccgctgatgg cgtcaatatt ttaagtaacg
    19201 aactggcgca tacttatctc aatatgctta cgcatgagga ccgccaacgg ctgacacaaa
    19261 ttatctgtgg gcagcaggtc aattttgttg atgtcctgac cagcaacaat accaatctgc
    19321 aaatcagctt cgtccattcg cgctatcgta atgaaaacgt ggccatttgt gtgctggtgg
    19381 atgtttcttc gcgcgtgaag atggaagagt cgttgcagga gatggcacaa gcagcggaac
    19441 aggcgagcca gtcaaaatcg atgttcctgg ccaccgtcag tcatgagctg cgaacgccgc
    19501 tgtatggcat tatcggtaac ctggatctgt tgcaaaccaa agagttaccg aaaggcgtcg
    19561 atcgtctggt gacggcaatg aacaactctt ccagcctgtt gttgaaaatt atcagcgata
    19621 ttctcgattt ctcgaaaatt gaatcagaac agttgaagat cgaaccgcgt gagttttcac
    19681 cgcgtgaagt gatgaaccac atcaccgcca actatttacc gctggtggta cgcaagcagt
    19741 taggcttgta ctgctttatt gaaccggatg tgccagtggc cttaaatggc gacccgatgc
    19801 gtttacagca ggtcatctcc aacctgttga gtaacgccat aaaattcacc gataccggct
    19861 gtatagtttt gcatgttcgc gctgatggcg attatctctc tatccgtgtt cgcgataccg
    19921 gcgtggggat accggcgaaa gaagtggtgc gcttgtttga tcccttcttc caggtcggaa
    19981 cgggcgtaca gcgtaacttc caggggactg gtctgggtct ggcgatttgt gaaaaactga
    20041 tcagcatgat ggacggcgac atctcggtag attcagaacc gggaatgggc agccagttta
    20101 ccgtgcgtat tccgttatac ggcgctcagt acccgcagaa aaaaggtgtg gaagggttga
    20161 gtggtaaacg ctgctggctg gcggtccgca atgcgtcgct ctgtcagttc ctggaaacca
    20221 gtttgcagcg cagcggcatc gtcgttacaa catacgaagg gcaggaaccg actcccgaag
    20281 atgtgttaat tactgacgag gtagtgaaca aaaaatggca gggcagagcg gtagtgacct
    20341 tctgtcgtcg ccatattggt attccgctgg agaaagcgcc aggggagtgg gtacatagtg
    20401 tggctgctcc gcatgagcta ccggcattgt tggcgcgtat ttatttgatc gagatggaga
    20461 gcgacgatcc tgctaacgct ctgccgtcga cggacaaagc ggtcagcgat aatgacgata
    20521 tgatgattct ggtcgtggat gatcatccga ttaaccggcg tctgctggca gatcagttgg
    20581 gatcgttggg ctatcaatgt aaaaccgcga atgatggcgt cgatgcgctt aatgtactta
    20641 acaagaatca tattgatatc gtgcttagcg acgtcaatat gccaaatatg gatggttacc
    20701 gcttgacgca acgcattcgt cagttgggac tgacgttgcc ggtaatcgga gtaactgcta
    20761 atgcgttggc tgaagagaag cagcggtgtc tggagtccgg tatggacagc tgcctgtcga
    20821 agccggtaac gctggatgtg ataaaacaga cgctgacggt atatgccgag agggtcagga
    20881 aatcgcggga atcgtaggac ggataaggtg tttatgccgc atctggcatt cagtgcaaat
    20941 gccagatgcg acgctgacgc gtcttatctg gcctacttta atgtaatctg ttgaaataat
    21001 gggaatcgta ggacggataa ggcgtttacg ccgcatccgg caatccgtgc aaatgccaga
    21061 taagacactg acgcgtctta tctggcctac aggtgattag tctttatctg ccggactcaa
    21121 cgtcacagaa gagagataat tcagcagagc aatatcgttc tcgacaccca gcttcatcat
    21181 cgcagatttc ttctggctac tgatggtttt aatactgcgg ttcagctttt tagcgatctc
    21241 ggtcaccagg aagccttccg caaacaggcg cagaacttca ctctcttttg gcgagagacg
    21301 cttgtcaccg taaccaccag cactgatttt ttccaacagg cgagaaacgc tttccggggt
    21361 aaatttcttc cctttctgca gcgcggcgag agccttcggc aaatcggtcg gtgcaccttg
    21421 tttcagcacg atcccttcga tatccagatc caataccgca ctaagaatcg ccgggttgtt
    21481 gttcatggtc agaacaatga tcgacaggct tgggaaatgg cgcttgatgt acttgattaa
    21541 ggtaatgcca tcaccgtact tatcgccagg catggagaga tcggtaatca acacatgcgc
    21601 atccagtttc ggcagattgt tgatcagtgc tgtagagtct tcaaattcgc cgacaacatt
    21661 cacccactca atttgctcaa gtgatttgcg aataccgaac aagactatcg gatggtcatc
    21721 ggcaataatt acgttcatat tgttcatgta ataggctacc ttgctacagc aagctcttga
    21781 cataactgtc aatgtcgctg atgtattttt ctattcctgg aacatccttc tcacgaatca
    21841 gatgttccag cgtttcacat aactgcttgc cgggtaccag atttagcatg gcaaatacgc
    21901 ctttaagacg atgagccgtt tgggctaacg cagcaaagtc gctggttgct gcttcagtat
    21961 atagcctctt aacatcatcc ggtactgtgt ctacaaagag cgcataatag ccgctggcat
    22021 ggagttgcgc attttcatct ccgcccagag gcgattctgt cacctcttcc tgcgccagtt
    22081 gcacttcaat taattgtaag accgcttcct gcatagcgtt gctcatattg aaattgacgc
    22141 acaattgacc aggcccaatt tcccgtacgc cagactcatc atcgcttaaa agcaagccag
    22201 aggcagtaag attagacgga ttatccgtta aaaagatatc ataatcttga ctaattaatc
    22261 tttcatcggg tgtgatacag gttgcacccc aattttctaa ctggcgagtg acaatattcc
    22321 gaatttctgc cgaagtaaca tccaccatta cgcagacatc atccagtaat cgctcttctt
    22381 cctcttcaac ttccgggtca gctgcgagca ttttgatatg cacagagtag cgtgtaccaa
    22441 gcccatcccg cgttttgatg tttaaatgac cgcccagttt acgcgccagt tgatcgctca
    22501 gccagaatgc cagcgggtcc gccttgccat agcgatcgtt ttgggtctgg ttgataaacg
    22561 ggaagtgcaa attatccatt tcatgaatgc ttacgccttc tccagtgtcc agaatgcgga
    22621 acgtcaggcg gtcttcggag gactcatcct gatcaacctc aagggtgatt tttcctaatt
    22681 gcgttgaggt cacggcatat tgcatcagta gcagcaaaat acgtcgtaag gcatcgcgat
    22741 cgccgcggcg catatcgtgt gctttcagat gattgttaat cagcagttgc agacctttac
    22801 gcttgatggc aggcaacact gaaggcacta cttcatcaat taaatcctgc acggagaaca
    22861 gctccgtctc acttttccag ctatcgtccg caagcatgtt cgctaactgt atttcatcga
    22921 ccagtcgcac cagcacatca gcctgattcg ccagttgttt gccttccggg gcgttgagtt
    22981 tagccgcgct ctccgccagg gactgtgcgg gttctttcag cgcatcgcca atgtttttca
    23041 taaaggtcat ccgcccctgc tggtttttct catacagacg ctgcgcctgc ttgagtttct
    23101 tgtttaccag cacttcgcga tcctgatcgc gaataatgaa aatttgtgtg cgcggcgcaa
    23161 cctggctgcg gaacatgcgg atctcataca gctcgttatt gatcgtcgcc tgaataatcc
    23221 cctgatgctg ttccgccatg gtggtgatgt tttgcagatt caaatgcggc agcaaatgat
    23281 cggcaatttt gttacttatg actgtgcggt ttgattcctg atcgtgaacc agcaggccga
    23341 gcggcagcag tgagactatc tcttcattaa ttgcccgtaa aatgcgcaat tcgttattga
    23401 ccgccgtgct ggggacgctt tctgtactgc ggctggagaa atggcggaat gtggtatagc
    23461 caaataacgc cagcgccagc aaaccgatgt tcagcagcag tggcagcaga atgttttgca
    23521 acgtatccag cagtaaggtg ccgtaaggaa cctgccagac caggcgcata tcggtagagt
    23581 tgagtgccga ggagatttca atcttcgtac tgttaaagtg gatactgacg ctatccgtcc
    23641 cttctttctc attttcattg tttcccgttg ccgtcgcgtc tggctcaagg cggaaactgt
    23701 ccagcggcat acccggtggg atcaaatcat taatcggcag atcaaaagcc acgaccgttg
    23761 ccagatgtcc cggctggttg aacgtggtac gcaaggtaaa gtaatgaccg ttctgccagg
    23821 ccaggcggcg catgttagaa aaactttcgc gttcatcgag ggcgttggcc tgttgcaaca
    23881 tctctgcacg acgtgaatca acaatgtcgc tgacggtcga ttctttaaat ccggaggtga
    23941 gatctttgag gggcagggtt gagatcagca ccagactgtt atcctgacca ttcaggtaat
    24001 acatcgacca cggtacattt tctgcgcccc acaatgtgtc cagataggtg gacatccgtt
    24061 gagtcatctc aagcgttgag ttgtcgtgag agccaaagat taacgcttcc gttttgcggc
    24121 gtggtttctc cagatagtag acatcctgtt tcaggcgcgt ctcttgtaaa ccttcgccgg
    24181 aggaggggga ggtcgtcgcg gcaatgttgt cgtagatctg ccaggtcacg taacgccagg
    24241 tatcgacgcg cttttggatt gcgtgggtaa tgtcgacaat ctggtaactt ttatctttca
    24301 gccaggcgtt aacggcgctt tgtaccatta cacccatcgt caccagtaac acaatgatca
    24361 acagtaaaaa gaagcgggta atgctccccg gtaggagtga aaagcgggtc gtggccgttg
    24421 tctctttctg acgcattcgt gtttatgacc tgttaaaact tcgcgaagtg atagggcagt
    24481 ataaagggta cagtgtgaaa ttccagactc ttacctgatt gatgattctc tattctccag
    24541 tgatatttat catccggcat tgggggaaat agatgtacaa gcgccatttt gctgtacaaa
    24601 taacctacaa aaagcccaac gaaattaatt gcaaataaac gaagattgct ggaaattatg
    24661 ctgatgttaa ttatttgtga aatagttaac aagcgttata gtttttctgt ggtagcacag
    24721 aataatgaaa agtgtgtaaa gaagggtaaa aaaaaccgga tgcgaggcat ccggttgaaa
    24781 taggggtaaa cagacattca gaaatgaatg acggtaataa ataaagttaa tgatgatagc
    24841 gggagatatt ctagttgcga gtgaaggttt tgttttgaca ttcagtgctg tcaaatactt
    24901 aagaataagt tattgatttt aaccttgaat taatattgct tgatgttagg tg
//
LOCUS       DAFGPF010000070        24229 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFGPF010000070 DAFGPF010000000
VERSION     DAFGPF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24229
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.070"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            218..667
                     /gene="rpiB"
                     /locus_tag="LSX49_003146"
     CDS             218..667
                     /gene="rpiB"
                     /locus_tag="LSX49_003146"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional allose-6-phosphate
                     isomerase/ribose-5-phosphate isomerase RpiB"
                     /protein_id="HBL7169524.1"
                     /translation="MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYP
                     HYASQVALAVAGGEADGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDT
                     NVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQRRN"
     gene            736..1092
                     /locus_tag="LSX49_003147"
     CDS             736..1092
                     /locus_tag="LSX49_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169525.1"
                     /translation="MKRFPLFLLFTLFTLFTLFTLFTLFTVPAQADIIDDTIGNIQQA
                     INDAYNPDRGRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDERQRQLDQER
                     QQLEDEERRMEDEYGR"
     gene            complement(1120..1878)
                     /gene="phnP"
                     /locus_tag="LSX49_003148"
     CDS             complement(1120..1878)
                     /gene="phnP"
                     /locus_tag="LSX49_003148"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HBL7169526.1"
                     /translation="MSLILTLTGTGGAQGVPAWGCECAACARARRSPQYRRQPCSGVV
                     KFNDAITLIDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDTIPVYGPP
                     DEQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTLKFLRNNQPQVMVIDCSHPPREDAPRNHCDLNTVLALNQVIRSPRV
                     ILTHISHQFDAWLMENALPSGFEAGFDGMEIEVE"
     gene            complement(1880..2314)
                     /gene="phnO"
                     /locus_tag="LSX49_003149"
     CDS             complement(1880..2314)
                     /gene="phnO"
                     /locus_tag="LSX49_003149"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HBL7169527.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            complement(2301..2858)
                     /gene="phnN"
                     /locus_tag="LSX49_003150"
     CDS             complement(2301..2858)
                     /gene="phnN"
                     /locus_tag="LSX49_003150"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HBL7169528.1"
                     /translation="MTGKLIWLMGPSGSGKDSLLAELRQREQTQLLVAHRYITRDASA
                     GSENHIALSEREFFTRAGQNLLALSWHANGLYYGVGIEIDLWLHAGFDVVVNGSRAHL
                     PQARARYQSALLPICLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCLTLNN
                     DGSLRQSVDKLLTLIHQKEKHHACL"
     gene            complement(2858..3994)
                     /gene="phnM"
                     /locus_tag="LSX49_003151"
     CDS             complement(2858..3994)
                     /gene="phnM"
                     /locus_tag="LSX49_003151"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBL7169529.1"
                     /translation="MIINNVKLVLENEVVHGSLEMQDGKIRAFAESQSHLSEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVEREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAAM
                     CRARHIALASHDDATHAHVAQSHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDQSNRFTLPQAVRLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRKGNHIHIDHVWRQGKRVF"
     gene            complement(3991..4671)
                     /gene="phnL"
                     /locus_tag="LSX49_003152"
     CDS             complement(3991..4671)
                     /gene="phnL"
                     /locus_tag="LSX49_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HBL7169530.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLQGASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKARGAAIVGIFHDETVREQVADR
                     LHPMGVSS"
     gene            complement(4782..5540)
                     /gene="phnK"
                     /locus_tag="LSX49_003153"
     CDS             complement(4782..5540)
                     /gene="phnK"
                     /locus_tag="LSX49_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HBL7169531.1"
                     /translation="MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIRYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVMELNLAVVIVTHDLGVARLLADRLLV
                     MKQGKVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            complement(5537..6382)
                     /gene="phnJ"
                     /locus_tag="LSX49_003154"
     CDS             complement(5537..6382)
                     /gene="phnJ"
                     /locus_tag="LSX49_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBL7169532.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     LIQTRHRIPETPLTEDQIVIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKSQ"
     gene            complement(6375..7439)
                     /gene="phnI"
                     /locus_tag="LSX49_003155"
     CDS             complement(6375..7439)
                     /gene="phnI"
                     /locus_tag="LSX49_003155"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HBL7169533.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTGMRLE
                     RRISAIYKDIPGGQLLGPTYDYTHRLLDFTLLANGETPTLTTADSEQQPSPHVFSLLA
                     RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDIFIVPEELGFAVNVGELLMTECEMVNGFIDPPDEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEQNHG"
     gene            complement(7439..8023)
                     /gene="phnH"
                     /locus_tag="LSX49_003156"
     CDS             complement(7439..8023)
                     /gene="phnH"
                     /locus_tag="LSX49_003156"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBL7169534.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLAAPLSNDIVNQSLRFHTNASLVNQPEQATFAVTDEAIS
                     SEQLNALSTGTAVAPEAGATLILQVTSLSGGRMLRLTGAGIAEERMIAPQLPKCILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            complement(8020..8472)
                     /gene="phnG"
                     /locus_tag="LSX49_003157"
     CDS             complement(8020..8472)
                     /gene="phnG"
                     /locus_tag="LSX49_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBL7169535.1"
                     /translation="MHADTATRQHWMSVLAHSQPAELAARLNALNINADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVLGRDKQHAERCALIDALM
                     QQNRHFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            complement(8473..9198)
                     /gene="phnF"
                     /locus_tag="LSX49_003158"
     CDS             complement(8473..9198)
                     /gene="phnF"
                     /locus_tag="LSX49_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HBL7169536.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDSGSLHDFLREQTGITLRRSQTRISARRAQAKECQRLEIPNLSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            complement(9219..9998)
                     /gene="phnE"
                     /locus_tag="LSX49_003159"
     CDS             complement(9219..9998)
                     /gene="phnE"
                     /locus_tag="LSX49_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HBL7169537.1"
                     /translation="MQTITIAPPKRSWFSLLSWAVVIAVLVVSWQGAEMAPLTLIKDG
                     GNMATFAADFFPPDFSQWQDYLTEMAVTLQIAVWGTALAVVLSIPFGLMSAENLVPWW
                     VYQPVRRLMDACRAINEMVFAMLFVVAVGLGPFAGVLALFIHTTGVLSKLLSEAVEAI
                     EPGPVEGIRATGANKLEEILYGVLPQVMPLLISYSLYRFESNVRSATVVGMVGAGGIG
                     VTLWEAIRGFQFQQTCALMVLIIVTVSLLDFLSQRLRKHFI"
     gene            complement(10103..11119)
                     /gene="phnD"
                     /locus_tag="LSX49_003160"
     CDS             complement(10103..11119)
                     /gene="phnD"
                     /locus_tag="LSX49_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7169538.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLNPAYAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIWKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQSVKDNKGLNEQDKLAKTTAIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            complement(11144..11932)
                     /gene="phnC"
                     /locus_tag="LSX49_003161"
     CDS             complement(11144..11932)
                     /gene="phnC"
                     /locus_tag="LSX49_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HBL7169539.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSVGSHIELLGRTVQREGRLARDIRKSRANTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSYFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGCSQQFDNERFDHLYRSINRVEENAKAA"
     gene            complement(12065..12508)
                     /gene="yjdN"
                     /locus_tag="LSX49_003162"
     CDS             complement(12065..12508)
                     /gene="yjdN"
                     /locus_tag="LSX49_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HBL7169540.1"
                     /translation="MPLSPYLSFAGNCSDAIAYYQRTLGAELLYKISFGEMPKSTQDS
                     AENCPSGMQFPDTAIAHANVRIAGSDIMMSDAIPSGKASYSGFTLVLDSQQVEEGKRW
                     FDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVIKQQPTQ"
     gene            complement(12668..13003)
                     /locus_tag="LSX49_003163"
     CDS             complement(12668..13003)
                     /locus_tag="LSX49_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HBL7169541.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
     gene            13406..15634
                     /gene="crfC"
                     /locus_tag="LSX49_003164"
     CDS             13406..15634
                     /gene="crfC"
                     /locus_tag="LSX49_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
                     /protein_id="HBL7169542.1"
                     /translation="MYTQTLYELSQEAERLLQLSRQQLQLLEKIPLSVPGDDAPQLAL
                     PWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPM
                     TALPTLIRHTPGQKEPVLHFSHVAPIDHLIQQLQQRLRDCDIKHLTDVLEIDKDMRAL
                     MQRIENGIAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVE
                     FVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISD
                     EEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVS
                     SMWGYLANRARHELANNGKLPAPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQ
                     LWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQ
                     LRQNIHQVEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDAVNAQLAALFQD
                     NSESLSEMRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELS
                     ESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTRLGVVREIFSRWLNQPD
                     WGRGNEKFPTETVDYSVLQRALSAEVDLYCQQMAKVMAEQVDESVTAGMNTFFAEFAS
                     CLTELQTRLRESMALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAE
                     RY"
     gene            15631..16509
                     /locus_tag="LSX49_003165"
     CDS             15631..16509
                     /locus_tag="LSX49_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcZ-like family protein"
                     /protein_id="HBL7169543.1"
                     /translation="MTKTLLDGPGRVLESVHPRFLVDLAQGDDARLPQAHQQQFRERL
                     MQELLARVQLQTWTNGGMLNAPLSLRLTLVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRQHSAFPELPQQIVALYEWFSARCRWKEKALTQRGLLVQAGEQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLRVKATQHLAESINAAPTTR
                     HYYHQWFASSTVSTGGDHADFLSWLGKWSTADKQPVCWSVTQRWRTVALGMPRLCSAQ
                     RLAGAMVEEIFSVNLV"
     gene            16773..18275
                     /gene="proP"
                     /locus_tag="LSX49_003166"
     CDS             16773..18275
                     /gene="proP"
                     /locus_tag="LSX49_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HBL7169544.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE"
     gene            18387..18476
                     /gene="pmrR"
                     /locus_tag="LSX49_003167"
     CDS             18387..18476
                     /gene="pmrR"
                     /locus_tag="LSX49_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HBL7169545.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFATY"
     gene            complement(18452..19552)
                     /gene="pmrB"
                     /locus_tag="LSX49_003168"
     CDS             complement(18452..19552)
                     /gene="pmrB"
                     /locus_tag="LSX49_003168"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HBL7169546.1"
                     /translation="MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIDAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWIRLKKDQYVANQI"
     gene            complement(19553..20221)
                     /gene="basR"
                     /locus_tag="LSX49_003169"
     CDS             complement(19553..20221)
                     /gene="basR"
                     /locus_tag="LSX49_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HBL7169547.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            complement(20218..21861)
                     /gene="eptA"
                     /locus_tag="LSX49_003170"
     CDS             complement(20218..21861)
                     /gene="eptA"
                     /locus_tag="LSX49_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HBL7169548.1"
                     /translation="MLKRLLKRPSLNLFSWLLLATFYISVCLNIAFFKQVLQVLPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLGSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMITNIIDTTPAESYALMTPRMLLTLGLSGVLAAIIACWIKIKPTTSRLRSVLFRGAN
                     ILISVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRSANLPLIR
                     IGEDAHRNPLMQNGKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGVCD
                     RVPHQNVTALNLPGQCINGECYDEVLFHGLEDYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCTQEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            complement(21965..23302)
                     /gene="adiC"
                     /locus_tag="LSX49_003171"
     CDS             complement(21965..23302)
                     /gene="adiC"
                     /locus_tag="LSX49_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HBL7169549.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            complement(23439..24200)
                     /gene="adiY"
                     /locus_tag="LSX49_003172"
     CDS             complement(23439..24200)
                     /gene="adiY"
                     /locus_tag="LSX49_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AdiY"
                     /protein_id="HBL7169550.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFLSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
BASE COUNT         5369 a         6300 c         6797 g         5763 t
ORIGIN      
        1 catttaatca ctttaaaaac atgatgttat ttgtttttct ggtttattag atgatagatg
       61 ttgccggata gtgagtgtct ttaacgctat tgcgctgcca gatgtaactc tgtaaaacag
      121 atcgggaagg ctgatttcat cgattttggg tgtttttaat tcatttaaat cacaaatgtt
      181 tttttattgt gaagttttgc gcgagcgggg aagatgaatg aaaaagattg catttggctg
      241 tgatcatgtc ggtttcattt taaaacatga aatagtggca catttagttg agcgtggcgt
      301 tgaagtgatt gataaaggaa cctggtcgtc agagcgtact gattatccgc attacgccag
      361 tcaagtcgca ctggccgttg ctggcggaga ggctgatggc gggattttga tttgtggcac
      421 tggcgtcggt atttcgatag cggcgaacaa gtttgccgga attcgcgcgg tcgtttgtag
      481 cgaaccttat tccgcgcaac tttcgcggca gcataacgac accaacgtgc tggcttttgg
      541 ttcacgagta gttggcctcg aactggcaaa aatgattgtc gatgcgtggc tgggcgcaca
      601 gtacgaaggc ggtcgtcatc aacaacgcgt ggaggcgatt acggcaatag agcagcggag
      661 aaattgagat tcatccacta cttgcatgga tgagtaatga ctaatgtgga tagagtttct
      721 ttttgaggtt ggctaatgaa acgctttccg ctatttcttt tattcacgct gttcacgctg
      781 ttcacgctgt tcacgctgtt cacgctgttc accgttccgg cccaggccga tattatcgat
      841 gacaccattg gcaatattca gcaggcgatt aacgacgctt ataaccctga ccgtgggcga
      901 gactatgaag attcgcgcga cgacggctgg cagcgtgaag tgagcgacga tcggcgcaga
      961 caatatgatg accgccgccg ccagtttgaa gatcgccgca ggcagctgga cgaacgccag
     1021 cgccagcttg atcaggagcg tcagcaactg gaagatgaag agcggagaat ggaagatgag
     1081 tatgggcgtt gaggtagggg ccggcgcggg tattttccct cactccacct caatctccat
     1141 cccatcaaac cccgcctcaa accccgacgg cagtgcattt tccatcagcc acgcatcaaa
     1201 ctggtggctg atatgggtca gaatcacccg tggcgagcgg ataacctgat tcagcgcaag
     1261 cacggtattt aaatcacagt gattacgcgg tgcatcctcg cgcggcgggt ggctgcaatc
     1321 aatcaccatt acctgcggct gattattgcg taaaaatttc agcgtttttt ccggcaggcc
     1381 tgcggtgtca gatagccacg ccacccggct gtgcgccgtt tccagtaaat agccgaaagt
     1441 gagtttcgaa tggttaagcg gcagcggcgt gacctgcaac ccctgcaaat caaacaccac
     1501 aaacggctcc accgtgtggc tgaaatcaag caggcccgga tgtttaaaca gatcgtcgca
     1561 gccctgctca tccggtggac cgtagaccgg gattgtgtcg cccacgcccc agcgcagcgg
     1621 aaacagcccc tgcacgtgat ccatatggta gtgcgtcagc aaaaactgct ggaacgatcc
     1681 gggcgaccag cgatcggcga gatcgtgcag cccggcgtcg atcagggtga tcgcgtcgtt
     1741 aaacttcacg acgccgctgc atggctggcg gcgatactgc ggtgagcgcc gcgctctggc
     1801 gcaggccgcg cactcacagc cccatgcggg aacgccctgt gcgccgccag tgccggtgag
     1861 cgtgaggatc aggctcatgt tacagcgctt tggtgaagcg gaaatggctc tgctcgtagc
     1921 cttcgcgcag atagaaacgg tgcgcgtcgt ggcgcttcac gttggtcgaa agctcggtca
     1981 tttcggcccc ggcctggcgg gcttcttctt ctgcccacgc cagcaacttg ctaccgacgt
     2041 tcaggccgcg cgcctgcggc atcaccacca actcctgaat ttcgccgatc cagttgacat
     2101 gatgcagatg aaactgcaaa tgcaggccga tcatgccgac aacttcgcca tccagcagcg
     2161 ccagatggta gcgcatgttc ggatcgcgca gattggcgtt aaaccccacg cgaaacgcgt
     2221 ggtggtcaaa ctccgcctgt tttagctcac aaatcagcgc gtaaactgcg tcggtgtcgt
     2281 actgcgtagc cgggcgaagc tcacaagcag gcatggtgtt tctccttctg atgaatcagc
     2341 gtcagcagct tgtcgaccga ctggcgcagg ctgccgtcat tattgagcgt aagacaatcc
     2401 tgaggagtat agcgggcggc gcgcgccagc cgggcgttaa tttcactggc gttttcgcgg
     2461 ccacggtttt ccaggcgctg gcgcaggatc tccggcgaaa cctgtaaaca gatgggcagc
     2521 agtgccgatt gataacgtgc ccgcgcctgc ggcaggtggg cgcgtgagcc gttaaccacg
     2581 acgtcgaatc cggcgtgcag ccagaggtcg atctcaatgc cgacaccgta atacaaacca
     2641 ttagcatgcc agctcaaggc caacagattt tgccccgcgc gggtaaaaaa ctcccgctcg
     2701 cttaaggcga tatgattttc acttccggcg ctggcatcac gcgtgatgta gcgatgcgct
     2761 accagtagct gggtttgttc ccgctggcgg agttccgcca gcaggctgtc tttcccggag
     2821 ccggacggac ccattaacca aatcagtttt cccgtcatca gaacaccctt ttaccctgac
     2881 gccagacgtg gtcaatatga atgtgattgc ccttgcgatg cgccagcacc aggtcggcgc
     2941 gtttgccctc gccaatcacc ccgcgatcct ggagattcag tgcctgggcc gggtttttgg
     3001 tcaccagcct caccgcctgc ggtagcgtaa agcggttgct ctggtcatcg gccacgcgaa
     3061 acgccgcatc cagcaggctg gcggggtagt agtcggaaga gaggatatcc agcaggccaa
     3121 gctgcgccag ttcactggcc gccacgttgc cggagtgcga accgccgcgc acgatattcg
     3181 gcgcgcccat cagtacgttc atgccgtgct tgcgcgaggc ttctgccgct tcgaatgtgg
     3241 taggaaattc ggcgatcacg ctgccaagct gatgggattg ggctacgtgg gcgtgcgtgg
     3301 cgtcatcgtg gctggcgagc gcaatgtgtc gcgcgcggca cattgcggcg atggattcgc
     3361 gattcggctg tgaccagcgt gcggcgagcg ccagttgctc ctcttcgtac tgttgcatct
     3421 gcgcatcggt gagcgagtat ttgccctgat aatattcacg atatttttcg cggttggcga
     3481 actggcgctg gcccggtgag tgatccatca gcgacaccag cgtcacgggt tctcgctcga
     3541 ccagtttttc aaacagcggc agcgtggtgt gatgcggcag ttcgcagcgt aggtgcagac
     3601 ggtgctcggc acggttgacg ccgcgtttct gcgtctcttc gatggcgttg atcatcttct
     3661 ccagattctc cagccgatcg ccgccgtcgc gtacatcacc aatcgccacg gcgtccagca
     3721 cggtggtgat gccgctcgcc accatcagcg cgtcgtggct gctcatcgcc gagtgggcag
     3781 gccagtcaac tttcgggcgc ggggtgaaga atttatccag attatcggta tgcagctcaa
     3841 tcagccccgg tagcagccag ccgccttcgc cgtccattgc ttctgacagg tgactctggc
     3901 tttcggcaaa ggcgcggatt ttgccgtcct gcatctccag agaaccgtgt accacctcgt
     3961 tttccagcac cagtttgacg ttattgataa tcatgaagag actcccattg ggtgcaggcg
     4021 gtcggcgact tgctcgcgta cggtttcgtc atggaagata ccgacgatgg ccgcgccgcg
     4081 ggctttggct tcgcggatca gttccactac ggcggcgctg tttttagcgt ccagcgaggc
     4141 ggtaggttcg tcgagcagca gaatggggta gtcgacgata aagccacggg cgatgttgac
     4201 acgctgctgt tcgccaccgg agaaggtcga tggcgcaagg tgccacaggc gttcaggcac
     4261 gttcaggcgg gtgaggagac gcgcggcttt agcggcgcag gcttcacgcg gtacgccggt
     4321 atcgagcagc ggctgcatca ccacttccag tgccgaaata cgtgggatga cgcgcagaaa
     4381 ctggcttacc cagccgacag tggttttgcg gatctccacc actttgcgcg ctggcgcggt
     4441 gaccaggtcg acccattcat caccgtgttt gatctggatt tgcccttcgt cgggtagata
     4501 gttggcatac agcgagcgta gcagagttga ttttccactg ccggaatggc cgtggagtac
     4561 cacgcattcg ccggcgttga cggtgagtga ggcgccttgt aatacaggca ggcgcacgcc
     4621 gttttgctgg tgcaggatga aggttttact gacgttttgt acgttaatca tttttcgcct
     4681 cgtggttcgg gtgtcggatg cgacgctgat gcgtcttatc cgacctacgg ggagcgcatt
     4741 tgtaggccgg ataaggcgtt tacgccgcat ccggcaccag ctcaattctg caaaaccgat
     4801 gacaccagca actgggtata cggatggtgc gggtcgtcga gcacgcggtc ggttaaccca
     4861 ctctccacca ctttcccttg cttcattacc agcaaacggt ccgccagcag acgggcgacg
     4921 cctaaatcgt gggtgacaat cactaccgcc aggttaagct ccatcaccag accgcggagc
     4981 aggtccagca ggcgcgcctg taccgacaca tccagcccgc cagtgggttc atccataaac
     5041 accagcttcg gatgcgtcac caggttgcgg gcaatctgca aacgttgctg catgccgccg
     5101 gaaaaggtgg tcggcaggtc gtcgatccgg ttggcgggaa tctccacctc ttccagccat
     5161 ttctgcgcgg tggcgcgaat atcgccgtaa tgacgcgctc cggttgccat caaccgttcg
     5221 ccgatattgc cgcctgccga cacctggcgg cgcaggccgt caagcggatg ctgatgcacc
     5281 acaccccatt cggtgcgcag caggcgacgg cggtcggcct cgctcatcgc gtacagcgaa
     5341 cggttctcgt agcgaatttc cccttgctgt ggtgtcaggc gggcggaaat tgatttcagt
     5401 agcgtggtct tcccggaacc ggactcccca acaatgccca gaacttctcc cggccataaa
     5461 tcaaaagaga catcgctgaa gcctttgccc ggggcataaa ggtgggtcag gttattgacc
     5521 gaaagtaacg gttgattcat tggcttttgg cctcgctctg ttggcggcaa taatcggtat
     5581 cggagcagac aaacatgcgg tttccggcgt catccagcac cacttcatca agatagctgt
     5641 gggtcgatcc gcagatggcg catggttcat cccactgctg gacggtgaac ggatgatcat
     5701 cgaaatcgag gctttccacg cgggtaaacg gtggcacggc atagatgcgc ttctcgcgcc
     5761 ccgcgccaaa cagttgcagg gcgggcatca tgtccatttt cgggttatcg aatttcggga
     5821 tcggcgacgg gtccatcacg tagcgcccgt tcaccttcac cggataggcg taggtggtgg
     5881 cgatatgacc gaagcgggcg atatcttcat acagcttcac ctgcatcacg ccgtactcct
     5941 ccagcgcgtg catggtgcgc gtttccgtct cacgcggctc aataaagcgc agcggttcgg
     6001 ggatcggcac ctggaagata actatctgat cttcggtcag cggcgtttcg ggtatgcggt
     6061 gacgcgtctg gataagtgtc gcatcgtccg tgcgctcggt ggtgttcacc ccggtcacgc
     6121 gcttaaagaa gttacgaatc gacacggcgt tggtggtgtc gtctgcgccc tggtcaatca
     6181 ccttcaacac gtcgctttcg ccaatcacgc tggcggtgag ctgaatgccg ccggttcccc
     6241 agccgtaggg catcggcatc tcgcgtccgc caaacggcac ctgataaccg gggattgcca
     6301 ccgcttttaa gatagcgcgg cggatcatgc gtttggtctg ctcgtcgagg taagcaaagt
     6361 tgtagccgct cagattagcc atggttctgc tcctgttgca gacgtttgag tagctccagt
     6421 tcggcctgga aatcgacgta gtgcgggagt ttgagatgcg aaacaaagcc tgcggcttcg
     6481 acgttgtcgg catgggccag cacgaactct tcatcctgtg ccggacctgt tgcgtgctcg
     6541 ccgtattccg gtgcctgcaa cgcacggtca accagcgcca tcgccattgc tttgcgctcg
     6601 ctcatgccga acaccagccc atagccgcgt gtaaaatgcg gtggttcatc cggcgggtcg
     6661 ataaaaccgt tgaccatttc acactcggtc atcaacaatt cgccgacgtt caccgcaaat
     6721 cccagctctt ccggcacaat aaatatatcg atatagccac tgcgaatttc gcctgcgaac
     6781 gggtgattgc gcccgtaacc gcgttgggtg gagtaggcca gcgccaacaa atagccttcg
     6841 tcaccgcgca ttaattgttg tagacgggaa gaacgcgaac agggataaac cggcggcgtg
     6901 cgggtgatgt cgtccggttg tgcgccgcta tcttcttcaa acttcgccag cccctgacgc
     6961 gccagcaggc tgaagacgtg tggcgacggt tgctgttcgc tgtcagcggt ggtcagcgtt
     7021 ggcgtttcgc cgtttgccag cagggtgaaa tcgagcaggc gatgggtgta gtcgtaggtg
     7081 gggccaagca gttggccgcc gggaatgtct ttataaattg ctgaaatacg ccgttcgaga
     7141 cgcatcccgg tggtgtcgag cggctcactg accgccagct tcgccagcgt ggtgcggtag
     7201 gcgcgcaaca gaaaaatcgc ttcgacgtta tcgccgctgg cctgtttcag cgccagcgcg
     7261 gccagctcgc ggtcggcaat accgccttcg gtcatcacgc gatctaccgc gaggttaagc
     7321 tgctgttcaa tctgggcgac gctcagttca ggcaaatcag tatcgccccg gcgtcggctc
     7381 tcttgcaggg cgtgggcggc gtcgatcgcc ttttcgcccc ctttcacggc aacgtacatc
     7441 agcacacctc cacatgagtg gttcgcggaa tagccagcag gcgctcgccg caggtcagga
     7501 tcaggtcgat gccgagcggg aacgggtgcg ggcgctcggt aagttcatga agaatgcact
     7561 ttggcagttg cggggcgatc atccgttctt cggcaatacc tgcgccggtg aggcgcaaca
     7621 tacgcccgcc gctcaggctg gtgacctgta aaatcagcgt tgcgcccgct tctggtgcaa
     7681 cggcagtgcc ggtggaaagg gcgttgagct gctcgctgga gatcgcctca tctgttaccg
     7741 cgaaggtcgc ctgttccggc tgattaacca gcgacgcgtt ggtatgaaaa cgcaggctct
     7801 gattgacgat atcgttgctc aatggcgcgg caagccacac cggcgtgtcg ttatcggcca
     7861 gcgtcagcag cacgctggtg gtggcgatat tcagcggctg ccagccgcgc ttgagctgat
     7921 gcagggcgac aatcacgccc ggctcgctca tggcctttaa caggcgacga aaactgtgct
     7981 gggcatcctg cacgggaagc ataaaagcgg tttccagggt catgcgttgt ctccgcgaac
     8041 catcgtaaag aagtcgaccc ggctggcgtt cacttcggcc tggcgcgcgg caatgcgtgc
     8101 catacggtca gcgtccagcg gggcgataag ggtttctgat aagttttgaa agtggcggtt
     8161 ttgctgcatc agcgcatcaa tcagcgcaca acgttcggcg tgctgtttgt cgcgccccag
     8221 cacccagcta tagccgagcg tgccgtcagt cagacgcacg gcggcgcggg tgagcgtggc
     8281 gtcgccagca aaaaagcgtt cgccggtgcc gcccattcgc gcctgaatct gcaccaggcc
     8341 agtttcagcg gcgcggatca cctcataatc ggcgttgatg ttcagcgcgt tcaggcgggc
     8401 tgccagttca gccggttggc tgtgcgccag cacggacatc cagtgctggc gggtcgcggt
     8461 atctgcgtgc attcagtgct ccatagtgaa ttcaatcatg tcggcgcgcg tcaggctgac
     8521 ggagtactcc gccgggctgc tttcaccgtc acggtggtta agggtgcgca cgcacagcag
     8581 cggcgacaga ttcgggattt caagacgctg gcactctttg gcctgggcgc gacgggcgct
     8641 gatccgcgtc tgactgcgtc gtagcgtaat ccccgtttgc tcgcgcagaa aatcgtgcag
     8701 cgaaccgctg tcgaaacgtt gcagcgtcgg ccagagggtg aggtccgcaa agtagtggtc
     8761 gattaaacag agcgcgacgc cgttgacccg acgcagggtg cgcaggtgga tgacgttctc
     8821 cccctcggtt atccccagcg cgtcagcgac gtgaccggag gcggggcgca gcaccgatag
     8881 caatttttcg ctggtgggat ggctgccctg gtccagcagg ttctggctaa aacgcgcctg
     8941 ggcgttgagc gggtaatcga acgggcgcat cagcaccagt acgccgacgc cctgacggcg
     9001 ctgtacccag cctttttcca ccagttggtc gatggcgcgg cgcagggtgt ggcggttcac
     9061 ctcaaagcgc gccgccagtt gctgctcggc gggaagatag tcgccgcagc ggtagtgttg
     9121 acgaagctcc tgctcaagtt ttgcggctat ctcctgatag cgtgttgggt agctggtcgg
     9181 atgtgtagac aagtgcatag atatcaatgc ctcgcttatc agataaagtg cttacgcaac
     9241 cgttgagaga ggaaatccag caggctgacc gtgacgatga tgagcaccat cagggcgcag
     9301 gtttgctgga actggaaacc gcgaatcgct tcccacagcg tgacgccgat cccgcccgcg
     9361 ccaaccatac cgacgacggt cgccgagcgg acgttggatt cgaagcgata gagagagtag
     9421 gaaatcagca gcggcatgac ctgcggtagt acgccgtaaa ggatctcttc cagcttgttg
     9481 gcaccggtgg cgcgaatgcc ctccaccggg ccgggttcga tcgcttccac cgcttcggaa
     9541 agcagcttgg agagcacgcc ggtggtgtgg ataaacagcg ccagcacgcc agcgaacggg
     9601 ccgaggccga cggcgaccac gaacagcatg gcgaagacca tttcgttaat ggcgcggcag
     9661 gcgtccatca ggcggcgtac aggttggtag acccaccacg gtaccaggtt ttcagcgctc
     9721 atcaggccga aggggatgga gagaaccacc gccagcgcgg tgccccagac ggcgatttgc
     9781 agcgtgacgg ccatttcggt gaggtaatcc tgccactggc tgaaatcggg cgggaagaag
     9841 tcggcggcga acgtcgccat gttgccgcca tctttaatca gcgtaagcgg ggccatttcc
     9901 gcgccctgcc acgagacgac cagcacggcg ataacaacgg cccagctcag aagcgagaac
     9961 cagctgcgct tgggtggggc gatggtgatg gtttgcatgt ttggctccgg tctgtaggcc
    10021 ggataaggtg cttgcaccgc atccggcatc aacgtctgca cattgtcgga tgcgacgccg
    10081 ggcgtcttat ccgacctacg atttactgca ccgctttact caccgaactc attgcgctta
    10141 acgcgttgtt caggcggtcc aaatcatcca gttgcgcctg aatggcggtg gtttttgcca
    10201 gcttgtcctg ttcgttcagc cctttgttgt ccttcacgct ttgcatctct ttaaacagtg
    10261 cgagctggcg aatcggcacc agttgcaagt cgctggaggc gcggaacggc gcccagccca
    10321 ggcgctccag caccgctttc tcttccggcg ttttgccgta attcataaag aagtcgtaga
    10381 tcttgtcttt agtggtttcg gaaagatttt tgcgccagac gatcggatcg ccagggatca
    10441 gcggtgattt ccagatcacc ttcagttctt tcagcttctc cggcgcggag gttttcagct
    10501 tgtcgaggtt ttcggtgttg ttggtggcga catccacttg cttgttagcg acggcgaggg
    10561 cgttggtttc atgcccggcg ttgacggtgc gcttaaagtc gctggcggag atattgtttt
    10621 tagcgaagac gtagtaaccg gggacgagga agccggaggt agagttagga tcgccattgc
    10681 cgaaggtgag atctttccgc ttcgccagca gatcgttcag gttgttgatc gggctatctt
    10741 tgttgacgat caacacgctc cagtaacccg gcgatccatc cgccgcgacc gtctgggcga
    10801 agacctgacc gttggcgcga tccaccgctt ccatcgccga caggttgccg taccaggcga
    10861 tatccacttt attgaagcgc atcccctgga taatgcccgc gtagtccggg gcaaagaagg
    10921 cgttgacctt tacgcccagc ttcttctcca tatcctgtaa gaacggcgtc cattgcggtt
    10981 tcaggttttg ctgtgattcc gttgaaataa tgccgaaatt cagcgccttt tcctgctctt
    11041 cggcgtatgc cggatttaac agggtgctga ggctgaacat gctggtgaag gccagcgagg
    11101 caattatctt agcgttcatt cgttttcctc aatgatgggg atgtcaggca gctttcgcgt
    11161 tctcttcgac gcggttaatg ctgcggtaga gatggtcaaa acgttcgtta tcaaactgtt
    11221 ggctgcagcc gtcgtagaag acgtgcccct ggcgcagggc gacgatgcgt tcgcagtagc
    11281 gcagggcgta atccacctga tgcagcgtga cgaccacggt aatgccgtcg ttctggttga
    11341 tgtcgcgcag ggtgtccatc acgatgcgtg ccgattccgg gtccagcgag gcgatgggtt
    11401 cgtcagcgag aatgaccttc gcctgctgca tcagcgcgcg ggcaatcgcc acacgctgtt
    11461 gctggccgcc ggagagtgtg gaaacgcgtt gatgggcaaa gtgcaccatg ccaacgcggg
    11521 tcagcgcctg taacgcgcgc tgtttctgct cgcgggtgaa gtagctaaaa caggttcgcc
    11581 agaatggcgt gctgccgagc gcgccaatca gcacgttctc cagtacgctc aggcgattca
    11641 ccaggttgaa ttgttgaaag atgtagccgg tgttggcgcg gcttttgcgg atatcgcggg
    11701 ccaggcggcc ttcgcgctgg actgtgcggc ccagcagctc gatatggcta ccgacagatt
    11761 tatcgccggt aatcaaaccg cttaagtgac gtaaaagggt ggattttccg gaacccgacg
    11821 gcccaagcag agccaccatt tcaccatgat gaatgttcag atcaaccgcg tgcagcgcct
    11881 gatgctgatt gaaggttttg gcgagcttct cgacacggat aatcgtttgc atgatgcagc
    11941 ctccctaaaa aagtggctcc atcgtggcgg attattgtga cgatttggtt aattaaaagt
    12001 gactaacaga tgaagagtta acgggaattc gatgacagtg cgggagggcg ggcctcccgg
    12061 cgggttattg cgttggctgt tgtttgatga cattaatcat ccacggtacg ccaaatttat
    12121 cggtgacttt gccaaagcca tgcgcccaga acgtttcctg ccaggccatt tcgatttttc
    12181 cgttggcggc aaggttatca aaccagcgtt ttccttcttc cacctgttga gaatcgagca
    12241 ccagcgtaaa gccggagtag ctggcttttc ctgacggtat agcatcgctc atcatgatgt
    12301 cgcttcctgc aatgcgcaca ttggcgtggg cgatggcggt atcgggaaat tgcattccgg
    12361 aagggcagtt ctcggcgctg tcctgcgttg attttggcat ttcgccgaag ctgattttat
    12421 agagcagttc cgcgcccaac gtacgttgat aataggcaat cgcgtcggaa cagttaccgg
    12481 caaaagagag gtagggactt aacggcatga tggtgacctc agttaagaga agccagttaa
    12541 gtgtagttcg aaatttatac agatgagagg gaagcctgat aagacgcggt cagcgtcgca
    12601 tcaggcagtc gccaccgttg ccggatgcgg cgcgagcgcc ttatccggcc taccgatcac
    12661 aatacaatca gttctttttc acaaactcag acttcagttt catcggacca aaaccgtcga
    12721 ttttgcaatc gatgttatgg tcgccttcaa ccaggcggat gttttttact ttggtgccaa
    12781 ttttcagcat cgaagagcta cctttcactt tcagatcttt aatgatggta acgctgtcgc
    12841 cgtcagccag cagattgccg ttagcatctt taacgatcag ctcgtcgctt tcctgtgcag
    12901 gttctgcgtc gttccattcg taggcacatt ccgggcagat gtacatgccg ttatcttcgt
    12961 aggtgtattc ggagttgcat tttgggcagt gtggtaatga catgtggatt tcctcaaaag
    13021 tcagcagggc aaaagcgcca aaaaacggca gattgccgaa aaaggccgca attatacaca
    13081 aaatccctga gtttgtcggg ggtactgctg attttagatg acgatcgttt tcatttgaaa
    13141 ggaaacgcaa aaagaaaata atctttttgc ctccatttat tatttaagat aaggttaatg
    13201 ctctactcgt tcttttttta attcacatga tgtttttatc tttctgacgt tttaaacgta
    13261 ttgggagatg ttatttattc taataaaaaa acaacacgct aaatataaaa ttatttcctg
    13321 cagtaattat aaaagccgaa aacagaactc aaaaacaatc tggctaaata aaagtaataa
    13381 aatttgcttt aaggaagaat attctatgta cacacagacc ctgtatgagt taagtcagga
    13441 ggctgaacgc ctgttacagc tttcccgaca acagttgcag ttactggaaa aaatacctct
    13501 ctctgtaccc ggagacgatg cgccacaact ggctttaccc tggagtcagc ctaatatcgc
    13561 cgaacgtcac gcgatgctga ataatgagtt gcgtaaaatt tcccggctgg aaatggtgct
    13621 ggcgattgtc ggtaccatga aagcagggaa atcaaccacc attaatgcca ttgttggtac
    13681 ggaggttctg cctaatcgca atcgcccaat gactgcgctg ccaacgctta ttcgccatac
    13741 gcccgggcaa aaagaaccgg tactgcattt ttcacatgtc gcgccaatcg accatttaat
    13801 tcaacaatta caacagcgcc tgcgtgattg cgatattaag catctgaccg atgtgctgga
    13861 aatagataaa gatatgcgtg cgcttatgca gcggatcgaa aatggcatcg ctttcgaaaa
    13921 atattatctg ggtgctcaac ctatttttca ttgtctgaaa agtttgaatg atttggtgcg
    13981 actggcgaag gcgctggacg tcgattttcc tttttctgct tacgccgcca ttgagcatat
    14041 tcccgtgatt gaagtggagt ttgtccatct ggcggggctg gagagttatc ccggtcagtt
    14101 gacgttactg gatacccccg ggccaaatga agccgggcaa ccgcatctgc aaaaaatgct
    14161 taaccagcag ctggcacgcg cctcggcggt actggcggtg ctggattata cgcaactgaa
    14221 atcgatctcc gatgaagagg tccgtgaggc aattttggcg gtggggcaat cggtgccgtt
    14281 gtatgtgctg gtcaataagt tcgatcaaca ggatcgtaac agtgacgacg ccgaccaggt
    14341 gcgggcactg atttccggaa cgctgatgaa aggctgtatt acgccacagc agatatttcc
    14401 ggtgtcgtcg atgtggggct acctggcgaa tcgggcgcgc catgagttag ccaacaacgg
    14461 taagttaccc gcgccagagc aacaacgctg ggtggaagat tttgcccatg ccgcgctcgg
    14521 caggcgctgg cgtcatgccg atctggcgga cctcgaacat attcgccatg ctgccgatca
    14581 gttgtgggaa gattcgctgt tcgcccagcc aattcaggcg ttgcttcatg ccgcttacgc
    14641 taacgcctcg ttgtatgctc tgcgatctgc cgcgcataaa ctgttgaatt acgcgcagca
    14701 ggcgcgggaa tacctggatt ttcgtgcgca cgggttaaac gtcgcttgtg aacaattgcg
    14761 gcaaaatatc catcaggtcg aagaaagttt gcagctattg caactcaatc aggcgcaggt
    14821 gagcggcgag attaaacatg aaatcgagtt ggccctgacc tccgccaacc actttctgcg
    14881 tcaacagcaa gatgcggtga atgcgcagtt agccgcgttg tttcaggata attcggagtc
    14941 gttaagtgag atgcgtaccc gctgtgagac actgttacag acggcgcaga acaccatcag
    15001 tcgcgacttt acgctgcgct ttgccgagct tgagtccacc ctttgccggg tgttaaccga
    15061 tgttattcgc cccattgagc aacaagtcaa aatggaattg agtgagtctg ggtttcgtcc
    15121 tgggtttcat tttcctgttt ttcacggcgt agttccccac ttcaacaccc gccagctgtt
    15181 cagtgaagtc atttcgcgcc aggaagcaac ggacgagcag agcacgcgtt taggcgttgt
    15241 gcgtgagatt ttttcgcgct ggttgaatca gcccgactgg ggacggggaa atgagaaatt
    15301 cccgacagag acggttgatt acagtgtgtt gcaacgagca ttaagcgcag aagtcgatct
    15361 ttattgccaa caaatggcta aagttatggc agagcaggtc gatgaatctg ttacggcagg
    15421 catgaatact tttttcgctg agttcgcttc atgtttgacg gaattacaga cgcgtttacg
    15481 cgaaagtatg gctctgcgtc aacaaaatga atcggtggtc aggctgatgc aacagcaatt
    15541 gcagcagact gtgatgactc acggctggat ttacaccgac gctcagctgt tacgcgatga
    15601 tattcaaaca cttttcacgg cagaacgata ttgaccaaga cgttactgga cggccccggt
    15661 cgcgtgctgg agtcggttca tccgcgcttt ttagtggatc tggcgcaggg cgatgatgcc
    15721 cgccttccac aagcccatca gcagcagttt cgtgaacgac tgatgcagga acttcttgcg
    15781 cgcgtgcagc ttcagacatg gacgaacggc ggcatgttaa atgcgccgct tagcctgcgt
    15841 ctgacattgg tggaaaaact ggcgtcgatg ctggatcccg gtcatctggc gctgacgcag
    15901 atcgcgcagc atctggcgct gctgcaaaaa atggatcacc gccagcactc tgctttcccg
    15961 gagctccccc agcaaattgt cgccttgtat gagtggtttt cagcccgttg tcgctggaag
    16021 gaaaaggcgt taacgcaacg aggcctattg gtgcaggcgg gtgaacagag cgagcaaatt
    16081 tttacccgct ggcgtgctgg ggcgtataac gcctggtcgt tgcctgggcg ctgttttatc
    16141 gttctcgaag agttgcgctg gggtgcattt ggcgatgcct gccgtctggg aagcccgcaa
    16201 gcggtggcgt tgttgctagg tgatttgcgc gtgaaagcga cacaacattt ggcagagagt
    16261 atcaatgcgg ccccgaccac gcgtcactat taccatcagt ggtttgcctc ttcgaccgtt
    16321 tcgacgggcg gggatcatgc tgatttttta agttggctgg gaaagtggtc tacggcagat
    16381 aaacaacccg tttgctggtc agtgacccaa cgctggcgaa ctgtcgcact ggggatgcca
    16441 cgactctgtt cagcgcagcg tctggcgggg gcaatggtcg aggaaatctt ctctgtaaat
    16501 ttggtgtaaa taatcagtta caccaatgag tcctaaacga aatgcatgtg tgaagttgat
    16561 cacaaattta aacactggta gggtaaaaag gtcattaact gcccaattca ggcgtcaact
    16621 ggtttgattg tacattcctt aaccggaggg tgtaagcaaa cccgctacgc ttgttacaga
    16681 gattgcatcc tgcaattccc gctccccttt tgcggccgtc gcgctgattt ttctggcgtt
    16741 tgcggaaatg ggccaactct gcgaggaaag ctatgctgaa aaggaaaaaa gtaaaaccga
    16801 ttacccttcg tgatgtcacc attattgatg atggtaaact gcgtaaagcc attaccgcag
    16861 catcactggg taatgcaatg gaatggttcg attttggtgt ttatggtttt gttgcttacg
    16921 cattaggtaa agtttttttc ccgggggctg accccagcgt gcagatggtt gctgcactcg
    16981 ccactttctc cgttcccttt ctgattcgac cgcttggcgg gctcttcttt ggtatgttgg
    17041 gcgataaata tggtcgccag aagatcctcg ctatcactat tgtgattatg tcgatcagta
    17101 cgttctgtat tggcttaata ccgtcctacg acacgattgg tatttgggca ccgattctgc
    17161 tgttgatctg taagatggca caaggtttct cggtcggcgg tgaatatacc ggggcgtcaa
    17221 tatttgttgc ggaatactcc cctgaccgta aacgtggctt tatgggcagc tggctggact
    17281 ttggttctat tgccgggttt gtgctgggag ctggcgtagt ggtgttaatt tcgaccattg
    17341 tcggcgaaga gaacttcctc gattggggct ggcgtattcc gttctttatc gctctgccgt
    17401 tagggattat cgggctttac ctgcgccatg cgctggaaga gactccggcg ttccagcagc
    17461 atgtcgataa actggaacag ggcgaccgcg aaggtttgca ggatggcccg aaagtctcgt
    17521 ttaaagagat tgccaccaaa cactggcgca gcctgttgac atgtattggt ctggtaattg
    17581 ccaccaacgt gacttactac atgttgctga cctatatgcc gagttatttg tcgcataacc
    17641 tgcattactc cgaagaccac ggggtgctga ttattatcgc cattatgatc ggtatgctgt
    17701 ttgtccagcc ggtgatgggc ttgctgagtg accgttttgg ccgtcgtccg tttgtgctac
    17761 ttggtagtgt tgcactgttt gtgttggcga tcccggcgtt tattctgatt aacagtaacg
    17821 tcatcggcct gatttttgcc gggttactga tgctggcggt gatccttaac tgctttacgg
    17881 gcgttatggc ttctaccttg ccagcgatgt tcccgacgca tatccgatac agcgcgctgg
    17941 cggcggcatt taatatttcg gtgctggttg ccggtctgac gccaacactg gcggcctggc
    18001 tggtcgaaag ctcgcagaat ctgatgatgc ctgcctatta cctgatggta gtggcggtgg
    18061 ttggtttaat caccggcgta accatgaaag agacggcaaa tcgtccgttg aaaggtgcga
    18121 caccggcggc gtcagatata caggaagcga aggaaattct cgtcgagcat tacgataata
    18181 tcgagcagaa aatcgatgat attgaccacg agattgccga tttgcaggcg aaacgtaccc
    18241 gcctggtgca gcaacatccg cgaattgatg aataagctga aacggatggc ctgatgtgat
    18301 gctgtcttat caggtcaatt gaactcttaa ggttcactta atctctgacg cgcatactct
    18361 cctccaggtt aacggaggag agtgcaatga aaaaccgtgt ttatgaaagt ttaactaccg
    18421 tgttcagcgt gctggtggtc agcagctttc tttatatctg gtttgccacg tactgatctt
    18481 ttttcagccg tatccaggcc cgcgtgccgg aagtctcttg tcggttttgc aggaaaaact
    18541 gcccgtgatg caactgtgta atgcggctga caatacttaa ccccagacca attccgccat
    18601 aacggctgtc cattcgtaca aatgctttac tcaactcccc gcatttactc tcatcaatac
    18661 ccggtccttc atcttcaacg gccatgaccg ctccgccatc ttcttgcagc ttaatcataa
    18721 tgttgctgcc ttgcgggcta taacgatggg cgttttctac caggtttcgc aataacatcc
    18781 gcagcagggt tgcatcaccc tgaacggtga tgtcggcggc gctctctggc aatagcaggg
    18841 tttgctggcg ctggtcgagc atggtactga gttcgtcata cgaggggaga atgacatctt
    18901 ccagcagttt tacatgttga taattaccgg aagaaaatga ctgtccggca cgcgccagtt
    18961 gcagcaactg ggagacgctc tccatcatct gatcaagtcg tgccactaac ggtgctacat
    19021 caatgtgatg cgttttcgcc agcagttcca gatgcaaacg cacccccgcc agtggcgttc
    19081 gcagttcgtg cgcgacgtca gcggtaaaca acctttcatt atcgagcgtg ctggtcaggc
    19141 gactgaccag atcgtttaac gccgaaacca ccgcatcgat ttcgagggtg gcgctatgaa
    19201 tggcaatggg cgttaagttg tcggcggtgc gcgcttccag ctctttttgc agctccgcca
    19261 gcggtcgggt gatgcggcgt accgcctgat agcagataaa tagcgtcagg ctaaccataa
    19321 agacgccggg gacaatcagg ctggcgaccg cctcgcggat ctcacgcatg atgtggcgat
    19381 cgttgttgcg attgtcgcgt agcgcctgct caaacagctg aatctgctcg gtactttcat
    19441 gccatagcca gaagacgctg atcagctcaa acaccaacaa aatggccccg atggtcaata
    19501 tcagccgttg gcgcagcgat attggtcggc gcagaaaacg catcagattc aattagtttt
    19561 cctcatttgc gaccagcata tagccaaatc cgcgcacggt gcggatacgg gctttgccca
    19621 ctttgtcgcg caggttatgg atatgcactt ccagggtgtt ggtcgagggc tcgttgtccc
    19681 agttgtagat atcgttgtag agaatttccc gatgcaccgg gctgcctgct ttaagcatca
    19741 ggcgcgacag cagagcatat tctttgggcg tcagaatcaa ctcttcaccg cccatccaga
    19801 cctgacggcg acccatattc agcgtcaggt tgccaacaat cagctcactt tcgccctgat
    19861 tattatggcg tcgtagcagg gcgcggatac gggcgtgcaa ctcttccagc gcaaaaggct
    19921 tcaccagata atcgtcggcc ccgacatcca gcccggcgat tttgtcggta agggtatcgc
    19981 gggcggtgag aattaacacc ggcagagtgt attttttctg ccggatacgg gcaagaaaat
    20041 gcagcccatc ttcatcgggt aagcctaaat ccagtaccac caggctgtaa tgaccggctt
    20101 caaggctttg ttccgccatc cgcgcggtgc tcacgccatc gcacgcgtag ccttcggttt
    20161 gcgccgccag aatcaatccc tgcaataaca gcgtatcgtc ttcaacaatc agaattttca
    20221 ttcactcact ctcctgcaag tttgcagaat atcatccgca gcctggtaat acttcgtctc
    20281 aacgccagtc aggcccaata aggttgagaa taaattgtct tgtgaatagt gttgcgtttg
    20341 cgcctgtttt tgcaggcagt tctggtcaac ctgataccgt ttttgataat cctccgatag
    20401 ccacagcagc atcggcacct gtttttggct atccggggcg atggcataag gcagaccgtg
    20461 cagatagatg ccattttcac ctaacgattc accgtggtca gaaagataaa ccaggctggt
    20521 ggtaaattta tcctgatgtt ctttcagcag attaatcgct ttatcaacaa tatagtcgac
    20581 gtaaaccagc gtgttgtcgt aagtgttcac cagttgctct tgggtacagg tctggatctc
    20641 gttagtgtcg caggttgggg taaatttcct gaactgcggc ggatagcggt tgtaataggt
    20701 cgggccgtgg ctgccgatgg tgtgtaagac aatcacgcca tcaccctgca ggttattgat
    20761 gtaatcttcc agcccgtgga acagcacttc atcatagcat tcgccgttga tgcactgacc
    20821 aggcaggttc agcgcggtga cgttctggtg aggtacgcga tcgcaaacgc ctttacagcc
    20881 gccatcgttg tcattccaca gcacgttgat gcccgctcgc tgaatgatat ccagcacgcc
    20941 ttcctggtgc tgtgccagct cttctttgta gtgctcacgc ggcatatccg agaacatgca
    21001 tggtactgaa actgccgttg ccgtgccgca agaggcggta ttagggaaat agaccacgtt
    21061 atcttttgcc agacgaggat tggtttcgcg tggataacca ttcagcgaga aattctctgc
    21121 gcgcgacgtt tctccgacga tcaaaatggt caggttttta cgtttcccat tttgcattaa
    21181 tgggttgcgg tgagcatctt caccaatgcg tatcagtggc aggttggctg accgctggtg
    21241 agagtaccac gaccagctag caacaatgct gttggacggg cttaaggatt tcaccagttc
    21301 tttgttgttg cgaaacagcg aggcatagtc tttgtagaac agtgcggcaa ccagcagaat
    21361 cagcagtaca gaaatcagga tgttggcccc gcggaaaaga acgctgcgca ggcgtgaggt
    21421 ggtgggtttg attttgatcc agcaggcaat aatcgcggct aatacgccac ttaaccccag
    21481 cgttaataac attcgtggcg tcatcagggc ataactttcc gccggcgtag tatcaatgat
    21541 attggtgatc attgaacggt cgatgacgat gccataggtc atgatgaaat attgcgcagc
    21601 cgcaccgacc agaataaaca ggcaggcgag tggacgatta agccataaga aagagcctag
    21661 tgtcaggaca atattaatca cgctgaatgc gacgaccggc atcgacaaga aaaccagcac
    21721 gttatgcagt gaatccagcg gtaacacctg tagcacctgt ttaaaaaagg cgatattcag
    21781 gcagactgag atataaaaag tagcaagtaa taaccaggag aataaattca aagagggtct
    21841 ttttagtagg cgcttcaaca tcacggtgtt tccatcgaac aaagtgcgca tatgctcgca
    21901 aagcaaaatt aagccaacct taagttctta aggttggctt ttatgtttgc tggattaagg
    21961 ggaattaatc tttgcttatt ggtgcatcta agggatacgg gtttttatgc agccggttgt
    22021 aattcagcgc atacatggcg gtgattacca tcagagtgac aaatgaccac ataacctctt
    22081 tcgcgccgga ccctactacg gcccagatgc agtagaggaa ggcaatggta gtaactgcca
    22141 ggtatgccgg gcgcgcttta ccaaagtgac cgtggccgag cagcagtaac gccgcacagg
    22201 tgtaaagata tggcaccagt gtaaagatga ccgacacgga agaaaccaga ccgaattctt
    22261 tggtcgcgtt tggcgaaatg ctactgagct ggaagatggt catcaaaata ccgacgataa
    22321 tcagccccgc cactggcgtg cccgctttat ttacacgggc aaaaatcggt gggaacagtc
    22381 cgtcatcggc agcggctttc gccgtttgac ctgccagcaa cgtccagccg cccagtgaac
    22441 ctaagcaacc cgcagctgcg cagaaggaaa caatggcccc ggcggtgtca cccaacgcca
    22501 tccgtgcggc atcaccgaat ggcgaagcag aaacgcgcag tgcggcatta gggatcatcc
    22561 ccataatcgc ggtggtagaa agtacatagc aaacggcagc aatcaatacc ccgccaatgg
    22621 tggcgatagg gacgttgcgt ttcgggtttt tcaccacacc tgcggcaacg gaggcacttt
    22681 ccacaccgat gaacgaccac agcgtaacgt taagggtact ttgaatcgca ccgaaggtgc
    22741 ccaggccgct gacgttccat gccgccatat aggtttcacc acggaaccag aaccagccaa
    22801 atacggcaat cccgacgatg gggatcagcg ccagcacggt agcaacggcc tgtacgcggg
    22861 tgatcatttt cggaccgaca atgttcagca ggacgaagat ccacagcacc acgacgcagg
    22921 tgatggttaa taccaatgga tctttcagaa tcgggaagaa gtaacttaaa tatcctacgc
    22981 caatgaccac catggcgata ttgccgatcc agcaggccag ccagtagagg acgttggttt
    23041 gataaccgag aaacggccca aagcagcggc gggcgtaagc gtaagaacca ccaggacttg
    23101 ggtcgaggaa cgacattttg gcgtatacca tcgagagccc cagcgcaccg ataatcgtca
    23161 ccaaccatcc ataaatggca atcccgccag tggaggccag gtttgcaggt aacagaaaaa
    23221 cacctgaccc cataatattc cccgacacca tcagggtgac ggggattaag cccactttgt
    23281 gagcatcagc atccgaagac ataattaaac tcctgcgaag gcgagcttcg tgacaataaa
    23341 ttacgtcata tcatacgcct gcattcgata gttgaattat tatcgaccgg gttatcgctg
    23401 atgccgttat taatatagct cttcgttaag gttaaaaatc aggcgacagt gcgttctctg
    23461 tgctgactaa cataatgcag aggcgtcata ccgtagaagt ctttaaagac agaaataaag
    23521 tacgacgtac tgttgtagcc gcaggactgt gatacctgag agatattttt accgtccatc
    23581 attaattcat ttacggcata gcgcatgcgg caggtggtga ttatttggct ataactggtg
    23641 ttttcgcttt tcagcttttt ctttaacaga cttgggctaa gacataaaca actggctacc
    23701 atactaagat tccagtcttt gtggatatcg ctttcaataa tttgataaac gctgtcactt
    23761 acacaattac gtaacatata catcattagt gaaaggaatt ttttactgtc gagaaaacgg
    23821 gatagcacag tgaataataa tgcacgtgtt cgttcctttt ctgactcagt ttcagcgggc
    23881 atcatgctat gttgcgcggc aacgcgaaag acgtctggcg tcaggcatgg aagggtgagg
    23941 atgggcgtag cgctacgttg ccatactggt atttgcgaga gatctttatt cagaaaccgg
    24001 aggtaatctt tgatgatgtc gtgactaata tgagcaacca aagtgttatt aagagaggag
    24061 acgtcgataa tattattttc acaatttaat aacgccatat ggttagcttt aaggctaata
    24121 ggttctttcc cattcaccct tatccagaca tctttttcag tcaataaaac aatacaaggt
    24181 tggtcgctgc aaatcctcat acatgtactc ctgagtgcga ataaaagac
//
LOCUS       DAFGPF010000071        24207 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFGPF010000071 DAFGPF010000000
VERSION     DAFGPF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24207
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.071"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            63..614
                     /locus_tag="LSX49_003173"
     CDS             63..614
                     /locus_tag="LSX49_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBL7169551.1"
                     /translation="MQNIAVVYYSGYGHTKLVAEKVAQGAHADLISIDNEGNITEQEW
                     EKLDAADAIIFGAPTYMGGAPWQFKKFADASSKAWFTRKWQDKVFGGFTNSASLNGDK
                     QVTLIYLQTLASQHGGLWVSLGQAPANVLASTREDVNNLGGSVGLLVQSPADAGAEQI
                     PTGDLDTAVKYGERVATITARLK"
     gene            complement(785..1777)
                     /gene="rpoS"
                     /locus_tag="LSX49_003174"
     CDS             complement(785..1777)
                     /gene="rpoS"
                     /locus_tag="LSX49_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HBL7169552.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(1840..2979)
                     /gene="nlpD"
                     /locus_tag="LSX49_003175"
     CDS             complement(1840..2979)
                     /gene="nlpD"
                     /locus_tag="LSX49_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HBL7169553.1"
                     /translation="MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAP
                     ANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENG
                     RIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
                     QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSA
                     NKMLPNNKPTATTVTVPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASE
                     GGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLV
                     REQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(3119..3745)
                     /gene="pcm"
                     /locus_tag="LSX49_003176"
     CDS             complement(3119..3745)
                     /gene="pcm"
                     /locus_tag="LSX49_003176"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HBL7169554.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(3739..4500)
                     /gene="surE"
                     /locus_tag="LSX49_003177"
     CDS             complement(3739..4500)
                     /gene="surE"
                     /locus_tag="LSX49_003177"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HBL7169555.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            complement(4481..5530)
                     /gene="truD"
                     /locus_tag="LSX49_003178"
     CDS             complement(4481..5530)
                     /gene="truD"
                     /locus_tag="LSX49_003178"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HBL7169556.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALLGSGEWGTQREALAFEQ
                     AAVAEETELQTLLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            complement(5527..6006)
                     /gene="ispF"
                     /locus_tag="LSX49_003179"
     CDS             complement(5527..6006)
                     /gene="ispF"
                     /locus_tag="LSX49_003179"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBL7169557.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            complement(6006..6716)
                     /gene="ispD"
                     /locus_tag="LSX49_003180"
     CDS             complement(6006..6716)
                     /gene="ispD"
                     /locus_tag="LSX49_003180"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBL7169558.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKRVVIAISPGDSRFAQLPLANHPRITVVDGGEERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            complement(6735..7046)
                     /gene="ftsB"
                     /locus_tag="LSX49_003181"
     CDS             complement(6735..7046)
                     /gene="ftsB"
                     /locus_tag="LSX49_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HBL7169559.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNNDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            complement(7239..7562)
                     /locus_tag="LSX49_003182"
     CDS             complement(7239..7562)
                     /locus_tag="LSX49_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HBL7169560.1"
                     /translation="MRNSHNITLTNNDSLTEVEDTTWSLPGAVVGFLSWLCALAIPML
                     IYGSNTLLFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLATVGIMFGALF
                     MWLLG"
     gene            complement(7611..8216)
                     /gene="cysC"
                     /locus_tag="LSX49_003183"
     CDS             complement(7611..8216)
                     /gene="cysC"
                     /locus_tag="LSX49_003183"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HBL7169561.1"
                     /translation="MALHDENVVWHSHPVTLQQREQHHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            complement(8216..9643)
                     /gene="cysN"
                     /locus_tag="LSX49_003184"
     CDS             complement(8216..9643)
                     /gene="cysN"
                     /locus_tag="LSX49_003184"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HBL7169562.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEVLPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSA
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            complement(9645..10553)
                     /gene="cysD"
                     /locus_tag="LSX49_003185"
     CDS             complement(9645..10553)
                     /gene="cysD"
                     /locus_tag="LSX49_003185"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HBL7169563.1"
                     /translation="MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            10805..11842
                     /gene="iap"
                     /locus_tag="LSX49_003186"
     CDS             10805..11842
                     /gene="iap"
                     /locus_tag="LSX49_003186"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HBL7169564.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIA
                     AHEGKTPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSV
                     EATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIM
                     LPLVKELAKAS"
     gene            complement(11968..12120)
                     /locus_tag="LSX49_003187"
     CDS             complement(11968..12120)
                     /locus_tag="LSX49_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HBL7169565.1"
                     /translation="MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVL
                     AYESKK"
     gene            complement(12386..13120)
                     /gene="cysH"
                     /locus_tag="LSX49_003188"
     CDS             complement(12386..13120)
                     /gene="cysH"
                     /locus_tag="LSX49_003188"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HBL7169566.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMAEEETRFFGLKRECGLHEG"
     gene            complement(13194..14906)
                     /gene="cysI"
                     /locus_tag="LSX49_003189"
     CDS             complement(13194..14906)
                     /gene="cysI"
                     /locus_tag="LSX49_003189"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HBL7169567.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            complement(14906..16705)
                     /gene="cysJ"
                     /locus_tag="LSX49_003190"
     CDS             complement(14906..16705)
                     /gene="cysJ"
                     /locus_tag="LSX49_003190"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HBL7169568.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSV
                     ATGTVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSDLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIAS
                     SQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPTN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GVLTRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            17024..17386
                     /gene="queD"
                     /locus_tag="LSX49_003191"
     CDS             17024..17386
                     /gene="queD"
                     /locus_tag="LSX49_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HBL7169569.1"
                     /translation="MSTTLFKDFTFEAAHRLPHVPQGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCIYRGE"
     gene            17464..18735
                     /locus_tag="LSX49_003192"
     CDS             17464..18735
                     /locus_tag="LSX49_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417246.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL7169570.1"
                     /translation="MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNL
                     SGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRA
                     RFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILHARYVVLAEGANSVL
                     AERHGLVTRPAGEAMALGIKEVLTLEPSAIEERFHLENNEGAALLFSGGICDDLPGGA
                     FLYTNQQTLSLGIVCPLSSLTQSSVPASELLTRFKTHPAVRPLIKNTELLEYGAHLVP
                     EGGLRSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHRE
                     PQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRVWPGLMQDISRDLWDQGNTP
                     VPPLRQLLWRHLRRHGLWHLTGDVIRSLRCL"
     gene            18726..18986
                     /locus_tag="LSX49_003193"
     CDS             18726..18986
                     /locus_tag="LSX49_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311649.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HBL7169571.1"
                     /translation="MSVARNLWRAADAPHIVPTDSVERQTAQRLINACPAGLFSLTPE
                     GGLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG"
     gene            19003..19578
                     /locus_tag="LSX49_003194"
     CDS             19003..19578
                     /locus_tag="LSX49_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HBL7169572.1"
                     /translation="MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTIS
                     NIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGF
                     FCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVC
                     DEEDARNAINAGVVALSTTNTGVWTLAKKLL"
     gene            complement(19726..20586)
                     /locus_tag="LSX49_003195"
     CDS             complement(19726..20586)
                     /locus_tag="LSX49_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417249.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBL7169573.1"
                     /translation="MNIVIVTINQDHAAIASWLAAQDFSGCTLAHWQIEPQPMVAEQV
                     LDALVEQWQRTPADVVLFPPGAFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHW
                     GNALTATLQTDKRPLCLSLARQAGADKNATLPSGMQQLNIVPGVLPDWLVSIENLKNV
                     IRDPLAEARRVLVVGQGGEADNQEIAMLAEKMGAEVGYSRARVMNGGVDAEKVIGISG
                     HLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEA
                     LVTNIHADCQ"
     gene            complement(20583..21362)
                     /locus_tag="LSX49_003196"
     CDS             complement(20583..21362)
                     /locus_tag="LSX49_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBL7169574.1"
                     /translation="MNILLAFKAEPDAGMLAEKEWQAAAQGNSGPDVSLLRSLLGADE
                     QAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPE
                     FVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLVWPCFTQVERFTLDAPFI
                     TLEQRTEHGVRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAAIIRKTVAVELPA
                     MQCLQLARAEQRRGATLIGGQTVAEKAQKLWQDYLRQRMQP"
     gene            complement(21340..22749)
                     /locus_tag="LSX49_003197"
     CDS             complement(21340..22749)
                     /locus_tag="LSX49_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169575.1"
                     /translation="MTVRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRI
                     AALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWIS
                     DHIGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFS
                     PRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLASAALPALLITLLRWG
                     TPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLFSSRYWRRTAFN
                     SVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHR
                     KFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIR
                     SLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLWAPETKA
                     LPLVAAGNVGGANEHSVSV"
     gene            complement(22771..24084)
                     /locus_tag="LSX49_003198"
     CDS             complement(22771..24084)
                     /locus_tag="LSX49_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001305791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBL7169576.1"
                     /translation="MPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLE
                     TVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPL
                     AQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKKVPRRAAGPDIRHIII
                     GNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYD
                     AEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWF
                     NNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDIT
                     MLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHH
                     HGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK"
BASE COUNT         5667 a         6636 c         6083 g         5821 t
ORIGIN      
        1 taatactcca catctttaaa acctgcctca aaaaatcatt cattagtaaa aaggatattt
       61 atatgcaaaa catagctgtg gtttattatt caggatatgg tcacactaaa ctggttgctg
      121 aaaaagtggc acaaggcgcc catgcagatt taatttcgat tgataacgaa ggaaatatca
      181 ctgagcagga gtgggaaaaa ctggacgcag ccgatgccat tatcttcggt gctcccacct
      241 atatgggcgg tgcgccatgg caattcaaga aatttgctga tgccagttcc aaagcgtggt
      301 ttacacgtaa atggcaggat aaagtcttcg ggggtttcac caacagcgcc agcctgaatg
      361 gcgataaaca agttacgctg atctatctgc aaacgctggc ttcacagcat ggcggtctgt
      421 gggtgagttt aggtcaggct cctgccaatg tgcttgcgtc aaccagggaa gatgtaaaca
      481 atctgggcgg ttcggtcggt ttgctggtgc aatctccagc cgatgcgggt gcagagcaaa
      541 tccctacggg cgatctggat acagccgtga aatatggtga acgcgtggcg acaattactg
      601 cgcgcttaaa atgatgattg ccgaatgtga tgctgacgcg tctatccggt cttctacatc
      661 taaaaagtgc cgtcccctgg tcagtcagat aaagttttaa cgctgtatcc gataacagtt
      721 caacatgtac caaaagaaaa aaagccagcc tcgcttgaga ctggcctttc tgacagatgc
      781 ttacttattc gcggaacagc gcttcgatat tcagcccctg cgtttgcagg atttcgcgca
      841 aacggcgcag gccttcaacc tgaatctggc gaacacgttc acgggtgagg ccaatttcac
      901 gacctacatc ttccagtgtt gccgcttcgt accccagcaa accgaatcga cgtgccagca
      961 cttcacgctg tttggcgttc agctcgaaca gccatttgac gatgctctgc ttcatatcgt
     1021 catcttgcgt ggtatcttcc ggaccattct ctttttcatc ggccaggatg tccagcaatg
     1081 ctttttcgga atcaccaccc agcggggtgt ctaccgaggt aatgcgctcg ttaagacgaa
     1141 gcatacggct gacgtcatca actggcttat ccagttgctc tgcgatctct tccgcacttg
     1201 gttcgtggtc cagcttatgg gacaactcac gtgcggttcg caggtaaacg ttcagctcct
     1261 ttacgatgtg aatcggcaaa cgaatagtac gggtttggtt cataatcgcc cgttcgatcg
     1321 tctggcgaat ccaccaggtt gcgtatgttg agaagcggaa accacgttcc gggtcaaact
     1381 tctctaccgc gcggatcagc cccaggttgc cctcttcgat caggtccagc aacgccagac
     1441 cacgattgcc ataacggcgg gcaattttta ccaccagacg caagttactc tcgatcatcc
     1501 ggcggcgaga ggcgacatct ccacgcagtg cgcgacgcgc aaaataaact tcttcttcgg
     1561 ccgttaacag tggtgaataa ccaatctcac caaggtaaag ctgagtcgcg tccagcacac
     1621 gctgtgtggc tccctgcgat aacagttcct cttcggccaa atcgttatca ctgggttcct
     1681 cttctactaa ggccttttcg tcaaaaacct caactccgtt ctcatcaaat tccgcatctt
     1741 catttaaatc atgaactttc agcgtattct gactcataag gtggctccta cccgtgatcc
     1801 cttgacggaa cattcaagca aaagcctggt tccgccgatt tatcgctgcg gcaaataacg
     1861 cagcgggttt acggatttcc ccttgtaacg aatttcaaaa tgcaagcgtg ttgaactggt
     1921 tccggtgcta cccatggttg ctattttttg ccccgccttc acttcttgtt gttcccggac
     1981 cagcattgtg tcgttatggg cgtaggcact caggtaatca tcattatgtt tgatgataat
     2041 cagattaccg tagccgcgca gcgcgttacc ggcataaaca acgcggccat ctgcggtcgc
     2101 gataattgcc tgtcctttgc tgcctgcgat atcaatcccc ttgttgcccc cctcagaagc
     2161 gccaaaggtt tcgatcactt tgccctcagt cggccagcgc caggtggaga taggcgtact
     2221 ggttgatgta ctgctgacag tcggctcggt tgtgcttgct gttggtaccg ttacaggcac
     2281 tgtgaccgtg gtcgcagttg gcttgttgtt cggcaacatt ttgttagcac tctgttcacc
     2341 cgaagactca gaatacgtaa ttgtcggttg cgacgcaaca gcaacggtgg aattttgtgc
     2401 aggcttgatc acaactcctt gctctgctgc gtcggcctgg gtaatggcat ttccgcctgt
     2461 gattggcgta ccggaagcat tacccacctg taaggtctga ccgacgttca gcgcgtatgg
     2521 tgcctgaata ttgttgcgct gagcaaggtc acggaaatcg ttgccagtaa tccaggcgat
     2581 atagaaaagc gtgtcgcctt ttttcacggt gtatgtactg ccgctataac tgcctttcgg
     2641 aatgttccca tactgacggt tgtagacgat tcgtccgttt tccatctgta ccggctgctg
     2701 agctactggc tgcacaggct ggatttgcgg ttgttgagta gcctgaattt gtggctgctg
     2761 taccggctga atttgcggtt gctgcgctgt agacgtcgtc cccattttcg gcggcggcgt
     2821 aatcaacata ccagaattgg tatttgcggg cgcattgcca ttaacggagc tgaccggtgc
     2881 cggtggattt gaagtgtcag aacagcctgc cagccatagc gaaaccagtg acaatgccgc
     2941 aatgcggcga acggtgaatt ttgggcttcc cgcgctcatt tatcccccag gaaaaattgg
     3001 ttaataacca gtgacataat taccgtgcaa ggcaccatac tgaacactgg aaaagatgtt
     3061 cacgatacgc tgacttgcgg caaaataacc aggaaaaatc caggtatttc ctcacgtttt
     3121 aagccagctc acccttcact aaagggacaa agcgcacggc ctccacggta tcgataataa
     3181 attcgcctcc ccgacgacgc acccgtttca aatactggtg ctcctcccct acgggtaaga
     3241 cgagaatccc gccttcgtcc agctgcgtca ttagcgcagt tggaatttca ggcggtgccg
     3301 ccgtaacaat gatagcgtca aacggcgcgc gtgcctgcca accttgccat ccatcgccat
     3361 gacgggttga aacattatgt aaatcaagat ttttcaggcg gcgacgcgcc tgccactgca
     3421 agcctttaat ccgttcaacc gagcaaacat gctggacaag atgcgccagg attgcagttt
     3481 gatatcccga accagtgcca atttccagca cccgcgactg cggcgttagc tcgagtaatt
     3541 cggtcattcg cgccaccata tacggctgcg aaattgtctg cccctgacct atcggcaagg
     3601 cgatattgtc ccaggctttt tgttcaaacg cttcatcaac gaatttttca cgcggcacgg
     3661 cggcaagtgc attcagcacc tgctcatcct gaataccttg cgcacgtaat tgatccagaa
     3721 gtgcttgtac gcgtctgctt accattgcgt gccaactccc acgctgttta accagtctga
     3781 aaccacatct tgcgcgctat gcgcagttaa atccacatgc agcggcgtga tggaaacata
     3841 gccctcatct accgcagcaa aatcggtccc cggaccggca tcacatttac cgcccggcgg
     3901 gccaatccag tacagcgtat tgccgcgcgg atcttgctgc gggatcacct gatctgccgg
     3961 atgtcgtgta ccgcagcgcg tcacgcgaat acctttgatt tgatccaatg gtaaatccgg
     4021 aacgttaata ttaagaatac gcccggtgcg cagcggctct ttacacaatg cgcgcaaaat
     4081 tgagcaggtt accgccgcgg cagtgtcgta atgtttatgc ccgtcaagcg agacggcaag
     4141 cgccggaaaa cctaaatgac ggccttccat cgcggccgct accgtaccgg aataaataac
     4201 atcatccccc agattcggcc cggcgttaat tccggacaca acaatgtccg ggcgcgggcg
     4261 catcagagca tttacgccaa gatagacgca atcggtcggg gttcccattt gcacagcaat
     4321 atcaccattt tcaaaggtaa acgtgcgcag ggaagattcc agtgtcagag aattagaagc
     4381 gccgctgcgg ttacgatcgg gggcgaccac ctgaacgtca gcaaactcac gcaaggcttt
     4441 cgccagcgtt tgtataccgg gtgcatgtac cccgtcatca ttactcagca atatgcgcat
     4501 aatcacctgt tgtgttgata agttccctga caacgctggt tgcaaaactt cccgccggaa
     4561 gccagaaacg gatttctacg gtgacgtcat cccaccagtt ccagcttaat tgttgcggat
     4621 acagcagcat cgctctgcgc gcggcttcaa ctttttcacg caccagtaaa gtttgtaatt
     4681 cagtttcttc ggcgacagct gcttgttcga atgccagcgc ttcacgctga gttccccatt
     4741 cgccactgcc cagcaatgcg gcggttatca ttagctcttt atcgttgacg cgacgctgta
     4801 attccgccag ttcttcggtg gttgcaacaa accagctacc acgtccggct aattgtagcg
     4861 catcgccgtc aacaacttga ttaacgtctg cttttttgag gcgctcagca acaatctgat
     4921 taaacaacgc actgcgggct gccgacaacc aaaaactccg tttattgcga tcgcgcaccg
     4981 gagtattggt ttgcgcccag cgcagcgcgc cctgcaagtt gctaccgcca atcccaaaac
     5041 gttgggcacc gaagtagttc ggtacacctt ttacgcaaat atcgatcaga cgttgttcaa
     5101 cgtcatcgcg attgctcact tcgcgcagaa ccagggtaaa ggcgttacct ttcagcgcgc
     5161 ctaaacgcag cttgcgcttg tgccgcgcat actccagcac ctggcagcct tccagttgaa
     5221 aggcgctcag atcgggcatc tctttgcccg gcacgcgagc gcataaccac tgttccgtaa
     5281 cagcatgttt atctttttgc ccagcgaagc tgacttcacg ggcatgaatt ttcaggaatt
     5341 tcgccagtgc atccgccaca aaacgggtat tgcagccatt tttgaggatt ctaaccagaa
     5401 tatgctcacc ttcaccatca ggctcaaagc ccaaatcttc caccaccaca aagtcttccg
     5461 gattggcttt cagcagcccg gtgccttgcg gtttaccgtg gaggtaagtg agattatcaa
     5521 actcaatcat tttgttgcct taatgagtag cgccaccgct tcacaggcaa tcccttcccc
     5581 acgtccggta aatcccagtt tttccgtagt agtggctttc acgttaacat catccatatg
     5641 gcagccgaga tcttcggcaa taaacacgcg catttgtgga atgtgcggca acatcttcgg
     5701 tgcctgagcg atgatagtga catcgacgtt gccgagggca taacctttcg cctgaatacg
     5761 acgccaggct tcgcgcaaca gctcgcggct gtcggcacct ttaaatgccg gatcggtatc
     5821 cgggaacagc ttgcctatat ctcccagcgc cgccgcgcca agcaatgcat cggtcaacgc
     5881 atgcagcgcc acgtcgccat cagaatgcgc cagcagccct ttttcgtaag gaatgcgtac
     5941 gccaccaatg ataattgggc cttcaccgcc aaaggcgtgt acgtcaaaac cgtgtccaat
     6001 tcgcattatg tattctcctg atggatggtt cgggtgaggt aaaattcggc cagcgccaaa
     6061 tcctccgggc gcgttacctt gatgttatcc gcgcggcctt caacaagttg cggatgaaaa
     6121 ccgcaatatt ccagcgccga ggcctcatcg gtaatggtag cgccttcatt tagagcgcgc
     6181 gtcaggcagt catgtaacag ctcacgaggg aaaaattgcg gcgtcagcgc gtgccataag
     6241 ccgttgcgat caacggtatg agcaatggca tttttgcccg gttcggcacg tttcatcgta
     6301 tcgcgcaccg gcgcagcgag gatccctccc gtgcggctgg tttcgctcaa cgccaacaat
     6361 cgcgcgaggt catcctgatg cagacaagga cgagcggcgt catgcaccaa tacccactgc
     6421 gcgtcgccag cggctttcag acctgccagc acggaatcgg cacgctcttc accaccatca
     6481 acaaccgtga ttcgtggatg attcgccaga ggaagttgtg caaagcggct atcgccagga
     6541 cttatggcaa tgacgacacg tttcacccgg ggatgcgcca gcagcgcatg caccgagtgt
     6601 tcaagaatgg tttgattacc gattgagaga tattgcttag gacattccgt ttgcattcgg
     6661 cggccaaatc cggccgccgg aaccacggcg caaacatcca aatgagtggt tgccatgtta
     6721 attcccgggc tgatttatcg attgttttgc cccgcagact gtgcgcgctt tgacgcgtca
     6781 ggcaccagac gataaaacgt ttcgcccggc ctggtcatgc tgagttcatt acgcgcacgc
     6841 tcttcgagcg cctcctggcc gccattgaga tcgtcaattt cggcaaaaag ctgatcgttt
     6901 cgcgctttaa gtttcgcgtt tgtagcttgc tgtgccgcca catcattatt gacgcgagta
     6961 tagtcatgta taccgttctt accgaaccac agcgaatact gtagccagac cagaatagcc
     7021 agcaacagca gcgttagttt acccatcctg ccccctgaaa aacggcatct tcatcccatg
     7081 catccgaaga cgactctaca tcctctgttg gggataccgc gacaacgcgg gcaaatgtac
     7141 cacatttgtc cattgttacg tatacccagg gcgtgcagaa aataatctca ttattagtta
     7201 cggattgaat tatgaacaga atagacggga aagaacaatt aacccaatag ccacataaac
     7261 agtgcaccaa acataatgcc aaccgtcgcc agagtgaaaa caatactgta gcgtagcttt
     7321 ccgtccatca atgaatgcag tgcaatcccc accactacag cgacgggcat cagcgccaga
     7381 aagaaaggcc aggtgtagat aaaaaagagc agcgtgttag agccataaat caacatcgga
     7441 attgccaacg cgcacagcca cgataaaaaa ccaaccacag cgcctggcag cgaccatgtg
     7501 gtgtcttcaa cctcagtaag gctgtcgtta tttgttaatg taatgttgtg gctgttacgc
     7561 atatctgatc ctgttacttt gacgaaccgg gcatgaaacc cggtggtgtc tcaggatctg
     7621 ataatatcgt tctgtctcaa cagatctaat aattgctgta ccaaatttgt tactaattgt
     7681 tcaccattga gatgaatttc tgccgattca ggcgcttcgt aaacggaatc tattcccgta
     7741 aagttgcgca gttcaccggc acgcgctttc ttatataaac cttttggatc gcgggcttcg
     7801 caaatcgcca gcggcgtatc gacaaacact tcgataaagc gcccttctcc tacgcgttcg
     7861 cgaaccatct ggcgttcggc gcggtgtggc gagataaatg cggtcagcac caccagtccg
     7921 gcttcaacca tcaaattcgc cacttcaccg acgcgacgga tattctcttt acggtcggca
     7981 tcgctaaaac cgagatcgct gcataatccg tggcgaacgt tgtcgccatc cagcagatac
     8041 gtactgacgc caagtttatg taacgcctcc tccagcgccc ccgcgacggt tgatttaccg
     8101 gaaccagaga ggccggtaaa ccacagcaca acaccacgat gaccgtggtg ctgttcgcgt
     8161 tgttgcagag ttactgggtg gctatgccag acgacgtttt cgtcatgcag agccattatt
     8221 tatctcccag taaatcgcgc gcaccccaat gcgggaaatg gcggcgaacc agggcattca
     8281 attccagttc gaatgcactg aattcagatg gcgcagcagt tgcctggcta actggttcgt
     8341 gcaccatacc ggcacctacg gtcacattac tcaggcgatc gataaaaatc agcccaccgg
     8401 taaccgggtt ttgctgataa cgatctaaca ccagtggctc gtcaaaggtg agatctacca
     8461 ggccgatgcc gttcagcggc aggttttcaa cttcgcgttg ggtaaggtta ttgatatcaa
     8521 cctgataacg aatgccatca acacgagcac gcgtcttctt accggcaatt ttgatgtcgt
     8581 aactctggcc cggggaaagc ggctgttccg ccatccatac cacatccacc gacgcgctct
     8641 gcacagccgg taacacttcg tctgccgcca gcagcagatc gccacggctg atgtcgatct
     8701 catccgtcag caccagggtg atcgcttctc cggcaaaggc ttcttcgcga tcgccatcaa
     8761 aggtcacgat ccgcgcgacg tttgattcca caccagaggg cagcactttg acacgttgcc
     8821 cgacttccac acgaccggat gccagcgttc cggcgtagcc acgaaaatcg agattcggac
     8881 ggttaacgta ctgcaccggg aagcgcattg gctgagcatc caccactcgc tggatctcca
     8941 cggtttccag cacttcgagc agtgtcggac cgctgtacca cggcatactt tcactttgcg
     9001 aagccacgtt gtcgccttcc agtgcggaga gcggcacaaa gcggatatcc agattacccg
     9061 gcagctgccc ggcaaaggtc agataatctt cacgaatacg ggtgaacgtc tcttcactgt
     9121 aatccaccag atccattttg ttgatcgcca cgaccagatg tttgatcccc aacagtgtgg
     9181 agataaaact gtgacgacgg gtttgatcga gcacgccttt acgggcatcg atcagtaaga
     9241 tcgccagttc acatgtcgat gcgccagtcg ccatattgcg ggtgtactgc tcgtgccctg
     9301 gggtgtcggc gataataaat ttacgcttct cggtagagaa atagcggtaa gccacgtcaa
     9361 tggtgatgcc ctgttcgcgc tcagcttgca ggccgtccac cagcagtgcc agatccagct
     9421 tttcgccctg ggtgccgtga cgcttactgt cgttatgcag cgatgagagc tgatcttcgt
     9481 agatttggcg ggtatcgtgt agcaggcgac caatcagggt acttttgccg tcatcgacgc
     9541 taccacaggt cagaaaacgc agcaggcttt tatgttgttg cgcaatcatc caggcttcga
     9601 cgccgccttc attggcgatt tgttgtgcaa gtgcggtgtt catcttaaaa atacccctga
     9661 cgttttttca gctccataga ccccgcctgg tcgcggtcaa ttacgcggcc ctgacgttca
     9721 ctggtggtgg aaaccagcat ctcttcgatg atctccggca gtgtttgtgc gtttgactcc
     9781 accgcgccgg tcagcggcca gcagcccagc gtacggaaac gcaccatccg ttttttaatc
     9841 acttcgcccg gttgcaggtc gatacggttg tcatcaatca tcatcaacat accgtcgcgt
     9901 tccagaaccg gacgttccgc agcgagatac agtggaacaa tgtcaatatt ttccagccag
     9961 atgtattgcc agatatcctg ctcggtccag ttagagagcg ggaagacgcg gatgctttcg
    10021 cctttgttaa tttgcccgtt gtagttgtgc cacagctccg ggcgctgatt tttcggatcc
    10081 cagcgatgga agcggtcacg gaaagagtag attcgctctt tagcgcggga tttctcttcg
    10141 tcgcggcgcg caccaccgaa ggcggcatca aaaccgtatt tgttcagcgc ctgtttcagg
    10201 ccttcagttt tcataatatc ggtatgtttc gcgctgccat gaacgaatgg attaatcccc
    10261 atcgctacgc cttccgggtt tttatgcacc agcagctcgc agccgtaggc tttagccgta
    10321 cgatcgcgga actcatacat ctcgcggaat ttccagccgg tatcgacatg cagcaacggg
    10381 aaaggcagcg tacctggata aaacgccttg cgcgccagat gcagcatgac gctggaatct
    10441 ttaccgatag agtagagcat caccggattt gagaattctg ccgccacctc gcgaataatg
    10501 tggatgcttt ccgcctccag ttgccgcagg tgggtaagtc gtttttgatc cataaccgtt
    10561 cctttgcaat accgctattt tcttgccatc agatgtttcg actataggga gcgtaagaga
    10621 acgaatgaaa ttaccaatta gaatgagtag ttccttaacg gaataacgat ttggcaaagc
    10681 taatatcaaa aagtgcttaa ggcaccggat ttcgggcgtt taggaagatt tgaaattgtt
    10741 ttagcgcagc ggcagtttca tactatggcg gtaaaaaaat ttgcatggta tttaaggact
    10801 cactatgttt tccgcattgc gccaccgtac cgctgccctg gcgctcggcg tatgctttat
    10861 tctccccgta cacgcctcgt cacctaaacc tggcgatttt gctaataccc aggcacgaca
    10921 tattgctact ttctttccgg gacgcatgac cggaactcct gcagaaatgt tatctgccga
    10981 ttatattcgc caacagtttc agcaaatggg ttatcgcagt gatattcgga catttaatag
    11041 tcggtatatt tataccgccc gcgataatcg caagagctgg cataacgtga cgggaagtac
    11101 ggtgattgcc gctcatgaag gcaaaacgcc gcagcagatc atcattatgg cgcatctgga
    11161 tacttacgcc ccgctgagcg atgctgacgc cgatgccaat ctcggcgggc tgacgttaca
    11221 aggaatggat gataacgccg caggtttagg tgtcatgctg gaactggccg agcgcctgaa
    11281 aaatacgcct accgagtatg gtattcgatt tgtggcgacc agcggcgaag aggaaggaaa
    11341 attaggcgct gagaatttac tcaagcggat gagtgacacc gaaaagaaaa atacgctgct
    11401 ggtgattaat ctcgataact taattgttgg cgataaattg tatttcaaca gcggtgtaaa
    11461 aacccctgaa gcagtaagga aattaacgcg cgaccgggcg ctggcaattg cccgcagcca
    11521 tggaattgcc gccaccacaa atccaggttt gaataaaaac tatccgaaag gcaccgggtg
    11581 ttgtaatgac gcagaaatat tcgacaaagc cggtattgct gtactttcgg tggaagcgac
    11641 taactggaat cttggcaata aggatggtta tcagcaacga gcaaaaacag ccgcattccc
    11701 tgcgggaaat agctggcatg acgtaagact ggataatcaa cagcatattg ataaggcact
    11761 tcctggaaga atagaacgtc gctgccgtga tgttatgcgg ataatgctac cgttggtgaa
    11821 ggagctggcg aaggcatctt aatgggtttg aaatgattac tcccttgcct gcaggaaatc
    11881 aatgccacca gaaacagagt ataaaaaagg ggtgcaggag gccaaaccat cacaattcag
    11941 tacgcggggt tttaccccgc gtggtggcta cttcttcgat tcgtaagcga gaactgcctt
    12001 aaactccata ccacgttctc tgatactcaa ctcacacaac gagtcgccta ccatcaacgt
    12061 gaatcccagt actgtacaac acagtacgat gattgccaca agggcatatt ttgtcagcat
    12121 gtcttgcctc cctgcaaaga agagactaac atccgaattg ctacgttcga acgcgagcct
    12181 caggttgata gaaatatcgc ctggggcttt tgtccatctg gaaccttgcg aatgcttaac
    12241 gccagacagc ctcaagcacc caatgccatt ctatacctgt taattttccc tgcgatgttc
    12301 acctttaaat gccggaatgc tgctcgcaaa aaataaaaac gcctccatca tttctgacag
    12361 aggcgtttaa tttatccggc aatatttacc cttcgtgtaa tccacattcc ctttttaagc
    12421 caaagaaacg cgtttcttct tccgccatgc cgggttccca tttacgggtt gtatgggtat
    12481 cgcccaccga taaatatcct tcatcccata atgggtgata tttcaggcca tgtttttgca
    12541 ggtactgata aatagttcgg ttatcccagt cgataatcgg cagcacttta aatacgccac
    12601 gctgaattgc cagcaccggt aaattggcgc ggctgccgga ttgttcacgg cgcaggccag
    12661 caaaccaggt ttgcgcattc agttctttca gcgcccggtt catcggttcg actttgttga
    12721 tgtcattgta cttttcaatg ccttcaacgc cctgctccca cagtttgccg tagcgtgctt
    12781 cctgccaggc ggcgctttcg gtagcacgat acactttcag gttgagcttg agtttgtccg
    12841 ttaactcgtc aataaagcgg taggtttccg ggaacagata gccggtatcg gtgaggatca
    12901 ctggaatatc cgggcgaatc tgattcacca gatgcaggct caccgccgcc tgaatgccaa
    12961 agctggaaga aagtacatat tcaccgggca gattatccag cgcccaggct acgcggcctt
    13021 cagcgtccag tttttccagt tgggcgttag tttccgccag cgccagaatc cggtctacct
    13081 ttggcagttc gttcagggcg tttagatcga gtttggacat aagttcctca ctgtttgcct
    13141 tgcctgatgc aacgctcaca cgtcttatca ggcctacaag accgggctga tggttaatcc
    13201 cacaaatcgc gcgccggatc gagcaccggg cgaatgatgc ccgcacgcac cgtaaagtcg
    13261 ccgaagcctt cacccgcttc gcgctctttc gcccagcgcc ctatcagttc atcaagcgac
    13321 gccaggattt ccggctcggt gatgttttct ttatacatcc gtgggatacg tgtcccaatg
    13381 cggttgccgc caagatgcag gttgtagcga cccggcgctt tccccaccag acccacttcc
    13441 gccagcatcg cgcgaccaca accgttcggg cagcctgtta cacgcatcac gatatgctca
    13501 tcgctgacac catgtttcgc cattaaatta tcgatgttgt cgataaaaga cggcaggaaa
    13561 cgctccgctt ccgccatcgc cagcgggcaa gtcgggaatg acacgcaggc cattgagttt
    13621 tcacgctgcg gcgtgacggc attcattaac ccgctttctt tggcgatctt ctcgatcttc
    13681 gctttctcgc tttccggcac gccggcgatg atcagattct ggttcgccgt aatgcggaaa
    13741 tcacctttgt ggatcttcgc gatctccagc aagccggttt tcagcgggcg ccccggataa
    13801 tcaagaattc gaccattttc gataaacagc gtcaggtgcc agttatcatc aatgccctta
    13861 acccagccaa tacgatcgcc gcgtccggta aactcatacg ggcgaatcgg ctcgaatttg
    13921 atccccgcgc gacgttcaac ttccgcttta aacgtctcaa cccctacgcg ctccagcgtg
    13981 tatttggttt tggcattttt acgatcggtt cggttacccc agtcacgctg agttgtcacg
    14041 acggcttccg ccaccgccag cgtatgctcc agcggcagat agccaaactc actcgccgtg
    14101 cgggcgtagg ttttcttgtt gccgtgttcg atggaaagcc caccgcccac cagcaggtta
    14161 aagcccacca gcttgccgtt ttcggcgatc gccacgaagt tcatgtcgtt ggcgtgcaga
    14221 tcgatatcgt tctgcggcgg gatcactacc gtggttttga acttacgcgg caggtaggtc
    14281 tgaccaagga tcggctcttc atcagtagtg gcgacttttt cctgatcgag ccagatctcc
    14341 gcatacgcgc gggtacgagg cagcagatgt tcagaaattt tcttcgccca ttcatatgct
    14401 tccgcatgca gctgcgactc gtaagggttc gaggtgcaga gtacgttacg gttcatgtcg
    14461 ttggcggtcg ccagcgcatc aagaccgacc gagtgcagca tctggtgcac cggtttgacg
    14521 ttctttttca gaatgccgtg gaactgaaac gtctggcggt tggtcaggcg aatgctgcca
    14581 tagatggtgt tttcaccggc aaatttgtcg atcgcctgcc actgtttagt ggtaatcacc
    14641 ccacccggca gacgacagcg aagcagcatc gcgtggcgcg gctccagctt ctgttcagca
    14701 cgttcggcgc gaatgtcgcg gtcatcctgc tgatacatgc cgtggaagcg gatcagcagg
    14761 aagttatcgc ccttaaagcc gccggtcaga ccgtcgttta aatcttccgc aatggtgccg
    14821 cgcaggtagt tgctttcaag cttcatgcgc tcggcgtctg tcagttttcc ttcgaccact
    14881 aaaggccctg gatgtttttc gctcattagt agacatctcg ctgataacgg cgctctacgc
    14941 gcagctcact taaaaattca tccgccgctt cggtgtccat gccaccaaat tcggcaatca
    15001 cttccagaag tgcctgctca acgtctttcg ccatgcgatt agcgtcgccg cagacataaa
    15061 tgtgggcacc gtcattgatc cagcgccaca gctctgcgcc ctgttcgcgc agtttgtctt
    15121 gtacgtaaat tttttctttt tgatcgcgcg accaggcgag atcgatgcgc gtcagcacgc
    15181 cttctttgac gtaacgctgc cattccacct ggtagaggaa atcttccgta aagtgtgggt
    15241 tgccaaagaa tagccagttt ttacccggcg cttcgtcggc ggcacgctgc tgcataaagg
    15301 cacggaacgg cgcgatgccg gtgccagggc caatcatgat caccggggtt tccggattgg
    15361 ttggcaggcg gaagttgtcg ttatgttcga taaatacgcg gacttcaccc tcttcttcca
    15421 cacgatccgc gaggaagctg gaggcaccac cggcacgggc gcggccttcc acgtcgtaac
    15481 gcaccacacc aacggtaacg tgcacttcgt tctcgacttc cgcctgcgag gaggcgatgg
    15541 aatacaggcg cggggtcagt gggcgcagca gattaatcag cgcttcggca tccagttgcg
    15601 ccggagagaa acgcaccatg tcgacaatcg gcgtcgtcgc ggcgtaatgc tgtaacttcg
    15661 ctttatcgcc caccagcggc agcagcgttt cgctgcgggt aagcgtggca tagttctcaa
    15721 caatgttggc ggtgttgacg gtcagttcga agtgccactg tagcgcttcg ttcagaggca
    15781 acgttttgcc ctcgacggtg acaggttcat cgcctttcag ccacagcagt tcgacaagtt
    15841 ctttcaccag tgccggatcg ttttgatacc agacgcccag cgcgtcaccc ggctggtaac
    15901 gcaggtcaga gtcacctaag tcaatttcaa tgtgacgaac gtctttttca gagttacgcc
    15961 cggtaatttt ctggttaaca gagaggctcg ccaccagcgg cgcgtctttg ctatacgggc
    16021 tggtgtggat ttcatttacc gtgccagtag cgacggattg cgaaggtgcc gcgacaggcg
    16081 cacgcgattt aagcgcatca accacgcggg cgcgccactc gctggcagca gcctggtatt
    16141 caacgtcggc atcgacacgg tcgagcaggc gttcaccgcc cagttccgcc agcttactgt
    16201 caaaatcttt cccggactgg cagaaaaatt cataagagct atcgccgagg ctaaacacgg
    16261 caaacgcggt gttttccagc tttggcgctt ttttggagaa caggaactta tgcagcgcga
    16321 cggcttcttc cggcggttcc ccttcccctt gcgttgacgt caccacgata agcagttttt
    16381 cgctggcgat ttgtttgaat ttatagtcgc ccgcgttcac cagcttaacg ttcagttttg
    16441 ccgctaataa atcatcgcgt aatgcttcag caacccgacg cgcattgcca gtttgcgagg
    16501 cggagataat agttataccc ggcatttctg cggcgggcgc tggcgtcgct gcaagcgcag
    16561 caggctgctg gttgagcacg ccccagaaat agccagaaac ccaggcaagc tgggtaggag
    16621 ttaaatcggt cgtggccgcc tgaaggcgtg ccagttgctc cgggttcaac ggaagcaacg
    16681 cggaaggtgg gacctgtgtc gtcatgcgtc gttatgttcc agtaagcaaa gctgtttctg
    16741 cgccctgtca gcgcccataa aacagaagag aaggtaaggt taacggggtg aacggtgtgg
    16801 attaaagacg ggatagcgat aactaataac caaatcgact aacctgtttt agcaatagtc
    16861 tttaacaaca aaatagatta accaacccaa tgaaaaacaa atgaatattg cccatcaata
    16921 agataaatca gcgattttgc gcaacaaagt cgttttagat aatgcgaaaa aacagccttt
    16981 ccggtactct acggcggttt tatcgtcatg tagagaaatt atgatgtcca ccacgttatt
    17041 taaagatttc accttcgaag ccgctcaccg cttgccgcac gtcccacaag ggcataaatg
    17101 tggtcgcctg cacgggcatt cctttatggt gcgactggaa attaccgggg aagtcgatcc
    17161 gcatacgggc tggattatcg atttcgctga actgaaagcg gcgtttaaac caacttatga
    17221 gcgcctcgat caccattatc tcaatgatat tccaggtctg gaaaacccaa ccagcgaagt
    17281 tttagcaaaa tggatttggg atcaggttaa acccgttgtg ccgctgttaa gtgcggtgat
    17341 ggtaaaagaa acctgcaccg caggttgtat ctatcgcggc gaatgataag agtgtgtcgg
    17401 cggtcaattt cccttaagta acgctatgtt agggtgttgt gttctggata tctggggcat
    17461 gacatggaag acgactgcga cattattatt atcggtgccg gaattgctgg caccgcttgc
    17521 gcgttacgct gcgcgcgagc gggtttatcc gttttgttac tggaacgagc ggagattccc
    17581 ggcagcaaaa atctttccgg cgggcgttta tatacccatg cgctcgcgga actcctcccg
    17641 caatttcacc tgaccgcgcc ccttgaacga cgcatcactc acgaaagtct ttctctgtta
    17701 acgccagatg gcgcaacgac gttttccagc ttacagcccg gcggtgaatc ctggagtgta
    17761 ttacgtgcac gattcgatcc gtggctggtt gccgaagccg aaaaagaagg tgtcgaatgc
    17821 atccccggtg cgacggtaga tgcactgtat gaagaaaacg gcagggtgtg tggtgtcatt
    17881 tgtggtgacg atattcttca cgcccgttat gtggtgctgg cagaaggtgc caacagcgtc
    17941 ctggcggaac gccacgggtt agtgactcgt cctgctggcg aagcgatggc attgggaatc
    18001 aaagaagtgc tgacgctgga accatccgct attgaagaac gttttcatct ggagaataac
    18061 gaaggcgcag cgttgttgtt cagcggcggg atctgtgatg acttacccgg cggcgcattt
    18121 ctttatacta atcaacaaac gctctcgtta gggattgttt gcccgctctc ctcccttacg
    18181 caaagtagtg ttccggcaag cgagctgctg actcgcttta aaacgcatcc ggcagtgcgc
    18241 ccgcttatca aaaacacgga attactggag tatggtgcgc atctggtgcc agaaggtggc
    18301 ctgcgcagta tgccggtgca atacgccggt aacggctggc tgctggtggg cgatgcgttg
    18361 cgcagttgcg tcaataccgg aatttccgtg cgcggcatgg atatggcgct aactggcgcg
    18421 caggcggcgg cacaaacgct gataagcgcc tgccaacacc gcgagccgca aaatctgttt
    18481 ccgctttatc atcacaacgt agagcgcagc ctgctgtggg atgttctaca gcgttatcag
    18541 catgttccgg cgcttttgca acgtcctggc tggtatcggg tgtggcctgg gttaatgcag
    18601 gatatttccc gtgatttatg ggatcagggg aatacacctg ttccaccgct gcgccagttg
    18661 ctctggcgtc atttacgtcg tcacggcctg tggcatctga cgggcgatgt tatcaggagt
    18721 ctgcgatgtc tgtagcccgt aatctctggc gcgctgctga tgcgccgcac attgttccga
    18781 ctgactccgt tgagcgccag acggcacaac ggttgattaa cgcctgtcca gcaggtcttt
    18841 tttcgctcac acctgaaggt ggcttacgtg ttgattatca cggctgcctg gagtgtggca
    18901 cctgccgttt gctgtgcgac gaatcaacac tacaacagtg gcgctatccg ccttccggat
    18961 tcggcatcac ctaccgcttt ggataaataa taaggataat ttatgcccct cttacacctg
    19021 ctccgccaga atccggtgat tgctgccgtt aaagataatg ccagcctgca actggcaatc
    19081 gactctgaat gccagtttat ttccgtgttg tacggcaata tctgcaccat tagtaatatc
    19141 gttaaaaaga ttaagaacgc cgggaaatat gcttttattc atgttgattt gctggaaggc
    19201 gcgtcaaata aagaagtggt gattcagttt ttgaaactgg taaccgaggc ggacggaatt
    19261 atcagtacca aagcctcaat gctgaaagca gcaagagcgg aaggtttttt ctgtattcat
    19321 cgactgttta ttgttgattc gatttcgttt cacaacattg ataagcaagt tgcgcaatcg
    19381 aatccggatt gtattgagat cctgccaggc tgcatgccta aagtgctggg ctgggtgacg
    19441 gagaaaatcc gccaaccgct gattgctggc gggctggtgt gcgatgaaga agatgcgcgt
    19501 aatgcgatta acgcgggtgt tgtggcgctt tccaccacga atactggggt ctggacgtta
    19561 gcgaaaaaat tgctttgacg ggataatcgt aacaagttga atttggtgtg atttgtaggc
    19621 tgcacgccac atccgacatt cagcgcctga tgcgacgctt gacgcgtctt atcaggccta
    19681 caagtcccca gcccagaacc atcggcagga tcatccggca gcacgttatt ggcaatctgc
    19741 gtgaatgttt gtcaccagtg cctccagcac cactttccag tcatcaacta cgccaacatc
    19801 tgcctgtgaa aataccgctg cactggcgtc atgattaatc gccaccacaa acttgctatt
    19861 gcgtacgccc gccattaacg ctgctgcgcc ggaagcgcca acaacaatac acacctcagg
    19921 tgccagcaga tgtccggaaa taccaatcac tttttcggca tcaacgccac cgttcatcac
    19981 tcgtgcccga ctgtagccca cttcggctcc catcttttct gccagcatag cgatttcctg
    20041 gttatctgcc tctccgccct gccccaccac cagcacccgt ctggcttcag ctaatgggtc
    20101 gcggataaca tttttcagat tttctatgct aaccagccag tcgggaagca cacctgggac
    20161 aatgttcagt tgctgcatcc cagagggcaa cgtggcgttt ttatctgctc ccgcctgacg
    20221 tgccagcgaa aggcatagcg ggcgtttgtc tgtttgcagc gtcgccgtca acgcatttcc
    20281 ccagtgggat ttgcgcacgc ttacggttgg aatatctaac gaagtcacct ggcagatgct
    20341 tgcaccatgt aaacgccagg ccagccgggt cgacagttca tcgccaaacg cgcccggagg
    20401 aaaaaggaca acgtccgcag gcgttcgttg ccactgttcc accagtgcat ccagcacctg
    20461 ttccgcaacc atcggctgtg gttctatttg ccaatgtgcc agggtacaac cgctgaaatc
    20521 ctgcgccgcc agccagctcg ctattgcggc atggtcctga tttattgtca caattacgat
    20581 attcatggct gcatcctttg gcgtaaatag tcctgccata gcttttgcgc tttttctgct
    20641 accgtttgcc caccaatcag cgtcgctccg cgtcgttgct ctgctcttgc cagttgcaga
    20701 cactgcatcg ctggcaattc gacagcaaca gttttacgga taattgctgc tttccccgca
    20761 gccattcgct ggcgcattcc cggaactggc aaggccactt caccgcactg acgcacggca
    20821 atcaccgcag gcaagcgaac ccggcaacag cgcaccccat gttcagtacg ctgttcgagg
    20881 gtgataaacg gtgcgtcgag agtaaagcgc tccacctggg tgaagcaggg ccagaccagc
    20941 atttccgcca gcaaaaatgg cgtttgccca ttctgccctt cgctgctttg gcagccggta
    21001 attatcagat ccagcggatt ctgacgctgc cattcggcaa tatggcgagc gacaaattcc
    21061 ggcgcaaagc gcagatctgc cgccgtctcc agcaatacag cttcctcaaa cccaagagcc
    21121 atgagatagc gcagccagtg caacgcccgt tcatccccca tgctcaacgc ggttaaagac
    21181 atcggcgtac cgttttttct ctgcgccaac agcagcgcag ctgcggcctg ttcatcagca
    21241 ccgagtaaac ttcgcagaag cgaaacatcc ggtccgctat taccctgagc cgccgcctgc
    21301 cactcttttt ccgccagcat tccggcatcc ggttcggctt taaacgctaa cagaatgttc
    21361 attcgcacct cctacatttc ccgccgccac cagcgggagt gctttggttt ctggtgccca
    21421 tagccaggtc acaacaaaac caaccaacaa cactgccgcc aggagtaata aggtggcttg
    21481 cattccccac tgcgccagca cccacggcag caggccagta cttaccgccg cccccaaccg
    21541 actcatggcg gtggcaaaac cgacgcccag cgagcgaatg tcagtaggaa aactttccgc
    21601 aggcaaaatg cccaccagat tactgactgc cgaaatggtg gtgctgaaga gaacaaaaag
    21661 cagcagcgtt aatgaactgc cggaaggcaa acaggccatc actaccagcg ttgccgccag
    21721 cagcaaaaaa cttcccagca aaaacttgcg atgtgccagc aggtgcgtca gaactaatcc
    21781 cagcagcgcg cccacaatta acaacgcatt aagcatcaga ctggcagtca gcgcatcttc
    21841 cagtccaata gtctgggcga tagttggcag ccaggtataa atcacaaacc atgggattac
    21901 gaggcagaca aagaagacgc tgttaaacgc tgtgcgccgc cagtagcgcg aagagaacaa
    21961 ggttttgatg tgtttatggg tcgccgttgc cacttcatcg cccagtaaaa catgcgggcc
    22021 aaaatagcga tgaacgatag cgtgagcttc tgcaaaacgc ccctggcgca gtagccagcg
    22081 tggcgattcc ggcgtgcccc aacgtagcag cgtaatcagc aaggctggta acgccgctga
    22141 tgccagcagc cagcgccagg cctccgggct ttcggaaata aagtgatgtc cggcaatact
    22201 tgccagcaca tagcctacgg tccacaccac actgaatgcg cccagcaaaa taccgcgatg
    22261 gcggcgcggg gaaaattcag ccagcaaggt gtgaccgact gagtaatcgc ctcccagacc
    22321 aatgccgatc aaaatgcgta atccaataag atgctctggc gtggtggcaa aaaattgcaa
    22381 gaacgaagcg agcgtaatca gcataaaact gaaggtgaag attttttgcc gcccgatatg
    22441 gtcggagatc caccccaaaa ccaggctgcc aagaaacaaa ccaagtaacg ccgagccgcc
    22501 gatcattccc gccataaacg gcgtcagttg catggcgggc gtaagctgaa taatggcata
    22561 accaatgacg ccgagaacat aaccgtcggt caggtgtgcg ccgaaagtga gcgcagcaat
    22621 tcgacagtga aaacggttaa gcggtaaatc atccattcgc accggtgaag tgttcatctt
    22681 taccccttca ttgtccggta ataagaacgg cttctcgcct gagaagccga aaaggcaacg
    22741 caccgtcatc gcggaacgct gcctgacaca ttatttttca atcggataga tagtacccgt
    22801 gttcataatg ccattaggat cgaactgctt tttcagccct tccagcaacg cccacgcgct
    22861 gccgtgttcc agtttgctcc agtgaacgcg atgtttaccg ataccgtggt gatgcaccat
    22921 cgaaccgccg aggcgaatgg tttcttcgca gatgattttg ttgagcggat tgtggtactt
    22981 gtcgatttcc tcttccggct tacagtcaac gacgttgtag tcgtagacga agtacatgtt
    23041 ggtgccgttc tgatagctat gagaggagtg accgcccagc atggtgatgt cgtcggcgtg
    23101 cgggaactcg gtacgaatac ggttaataac gctttcgtag atttcgtgaa tgcagctcca
    23161 gcagccggac acttcagtgg taaagcccat gttgccggtt ttgaggatct gcacacgttc
    23221 ggcagccact ttatccggtc cccagttcag gttgttaaac caggtttcga tcagcttgct
    23281 gtccacgcgc tggcactgcg ggtagcgcgc cacgatttca gcaatccctt cacccgtcgc
    23341 cttcgcaatg cgagggttac cttcagccat aaagatcagc acgcatttgc cgtcggcaaa
    23401 atgggtgaag tgttgggtgc catcttcagc atcatacaaa cgagcaatcg acggacgata
    23461 cccttccacc atgatttcac gcaggatgtt gaagccggtt ttcatatctt ccaggatata
    23521 gccgtagaag agattgtttt ccggcgtaaa tttgaagatt ttcactgtga cttcagtgat
    23581 atagcacagt gcaccttcgt tgccgatgat gatatgacga atgtccgggc cagccgcgcg
    23641 acgtggcact tttttaatgc gtgtgacggt gccatctgcc agcaccgctt ccagaccaac
    23701 gaccatatct tcgattgcgc cgtagagtgt ggagaactgc ccgatactgc gggtcgccac
    23761 caagccgccc atctgcgcca gcggctttga ctgcggagaa tgccccgtgg tgtaaccttt
    23821 ttcgcgcaat gcgttttcca gcacctccag cggaacgcca cattgcgccg tggcctgcat
    23881 attctcaata tcaatattaa tgatttgatt catggcggag ccgtcgagca ccaccgagtt
    23941 ttccacaacg gtttccagtc caccttcggt ggcggaagca ccggtacgtg gcacaccgtt
    24001 aattttgtgc gcattcataa aattcagcac acgggatact tgttctgtgg aaccgagttt
    24061 tacgaccgct gccggaatcg gcaaagtata aattccatga atatccggaa atttacgaaa
    24121 acggtcaata ctgtttttct ttaataccgt ttcatcggta ataacgcgat ctgcaccaac
    24181 aatttccttt agctggtcga caatcgc
//
LOCUS       DAFGPF010000072        23601 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFGPF010000072 DAFGPF010000000
VERSION     DAFGPF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23601
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.072"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            45..725
                     /locus_tag="LSX49_003199"
     CDS             45..725
                     /locus_tag="LSX49_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HBL7169577.1"
                     /translation="MSMKTLLNVLTIFSLGTLTGCDYIEKASLIDDLAKQQELQKSKI
                     EELEKQQEQYKNKAELFEKQQNNITNSTRILASIVKTVKEKQDEFVFTEFNPLQTQYF
                     ILNNGSVGLAGRVLAIDAVENGSVIRISLVNLLSVPVSNIGFHATWGNEKPTDAKALA
                     KWQQLLFNTTLNSTLQLMPGQWQDINLTLKGVSPNNLKYLKLSINMANLQFDTVQPAE
                     TRQRKNKK"
     gene            769..4965
                     /locus_tag="LSX49_003200"
     CDS             769..4965
                     /locus_tag="LSX49_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YadA-like family protein"
                     /protein_id="HBL7169578.1"
                     /translation="MNKIFKVIWNPATGSYNVASETAKSRGKKSGRSKLLISALVAGG
                     LLSSFGALADNYEGQPVDYGNGSAGDGWVAIGKNSKANTFVNGSGASTALGYDAIAEG
                     EYSSAIGSRTHAIGGASMAFGVSAQAIGDRSVALGASSVATGGRSMALGRYAKTNGFT
                     SLAIGDTALADGEKTIALGNTAQAYEIMSIALGDHANASKEYSMALGASSVASAANAI
                     AVGRDSAANGTDSLALGRLSLASAANAIAMGAESEAAENATAIGFNADAIGKSSLALG
                     DNASAGETNSIAIGQGSEASKLDSIALGSNSRSAGENAIALGNNSNAGGKNSLAFGFN
                     TTANGDNAVAIGANSSAGADNTVSVGSSSLKRKIVNMGNGDINNVSSDAINGSQLYAI
                     SKSVSDRLGGYHDDPDNVINSDGTLKAPTYYLQSGQYNNVGEALQSIDNNTLHWDSKS
                     NKYSASHTVFNANGSVKSTSAKNIITDVADGTISATSSDAVNGSQLYNLKQDALLWDG
                     TAFSAKHGTSNTDSKITNVLAGTVSSTSTDAINGTQLQSTASTITSYLGGGAAMSNDG
                     VFTGPQYNIGGKNYTNVGAALTALDNDALLWDATANSNTGAFSAAHGTLKTASKITNV
                     ANGDILANSYDAINGSQLYSLADSFTSYLGGGADINNAGVLIAPTYTIGSKTYNNVGD
                     ALNAINSSFSTSISDALLWDSTANKFSAKHGGTNSIITNVADGTISSTSSDAVNGSQL
                     YDTSKYIADALGGDAEVNADGTMTAPTYSIANEDYHSVGEALDALDDNALLWDEDAGA
                     YNASHDGNASKITNVAAGDLSTTSTDAVNGSQLNATNILVTQNSQMINQLAGNTSETY
                     IEENGAGINYVRTNDNGLAFNDASASGIGATAVGYNSVAEGDSSVAIGQGSSSSVDTG
                     IALGSSSVSSRVIVKGSRNTSVTENGVVIGYDTTDGELLGALSIGDDGKYRQIINVAD
                     GSEAHDAVTVRQLQNAIGAVATTPTKYFHANSTAEDSLAVGEDSLAMGAKTIVNGNAG
                     IGIGLNTLVLADAINGIAIGSNARANHADSIAMGNGSQTTRGAQTNYTAYNMDAPQNS
                     VGEFSVGSEDGQRQITNVAAGSADTDAVNVGQLKVTDAQVSQNTQSITNLNTQVTNLD
                     TRVTNIENGIGDIVTTGSTKYFKTNTDGADANAQGKDSVAIGSGSIAAADNSVALGTG
                     SVADEENTISVGSSTNQRRITNVAAGVNATDAVNVSQLKSSEAGGVRYDTKADGSIDY
                     SNITLGGGNGGTTRISNVSAGVNNNDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKT
                     ESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGVSMVSANGRWVYKL
                     QGSTNSQGEYSAALGAGIQW"
     gene            5383..7038
                     /gene="lldP"
                     /locus_tag="LSX49_003201"
     CDS             5383..7038
                     /gene="lldP"
                     /locus_tag="LSX49_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HBL7169579.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFTSGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP"
     gene            7038..7814
                     /gene="lldR"
                     /locus_tag="LSX49_003202"
     CDS             7038..7814
                     /gene="lldR"
                     /locus_tag="LSX49_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HBL7169580.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGEKEKIQLCFEATLSEDPDLASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFVGDADGARKAM
                     MAHLSFVHTTMKRFDEDQARHARITRLPGDHNEHSREKNA"
     gene            7811..9001
                     /gene="lldD"
                     /locus_tag="LSX49_003203"
     CDS             7811..9001
                     /gene="lldD"
                     /locus_tag="LSX49_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HBL7169581.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAK
                     GNAA"
     gene            9049..9522
                     /gene="trmL"
                     /locus_tag="LSX49_003204"
     CDS             9049..9522
                     /gene="trmL"
                     /locus_tag="LSX49_003204"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBL7169582.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD"
     gene            complement(9575..10396)
                     /gene="cysE"
                     /locus_tag="LSX49_003205"
     CDS             complement(9575..10396)
                     /gene="cysE"
                     /locus_tag="LSX49_003205"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBL7169583.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(10476..11495)
                     /gene="gpsA"
                     /locus_tag="LSX49_003206"
     CDS             complement(10476..11495)
                     /gene="gpsA"
                     /locus_tag="LSX49_003206"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL7169584.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(11495..11962)
                     /gene="secB"
                     /locus_tag="LSX49_003207"
     CDS             complement(11495..11962)
                     /gene="secB"
                     /locus_tag="LSX49_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HBL7169585.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(12026..12277)
                     /gene="grxC"
                     /locus_tag="LSX49_003208"
     CDS             complement(12026..12277)
                     /gene="grxC"
                     /locus_tag="LSX49_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HBL7169586.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(12418..12849)
                     /locus_tag="LSX49_003209"
     CDS             complement(12418..12849)
                     /locus_tag="LSX49_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL7169587.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            13093..14637
                     /gene="gpmM"
                     /locus_tag="LSX49_003210"
                     /gene_synonym="pgmI"
     CDS             13093..14637
                     /gene="gpmM"
                     /locus_tag="LSX49_003210"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBL7169588.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRTFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            14647..15930
                     /gene="envC"
                     /locus_tag="LSX49_003211"
     CDS             14647..15930
                     /gene="envC"
                     /locus_tag="LSX49_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HBL7169589.1"
                     /translation="MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADE
                     RDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNK
                     QIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEA
                     TRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            15934..16893
                     /locus_tag="LSX49_003212"
     CDS             15934..16893
                     /locus_tag="LSX49_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HBL7169590.1"
                     /translation="MFPFRRNVLAFAALLALSSPVIAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVL
                     QQLVYNLPPDITLVKASSLLNEPQVDTSTPPKNTVPDTPRNPFRGVKLCKPKKPLEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKLNASAN"
     gene            complement(16880..17914)
                     /gene="waaH"
                     /locus_tag="LSX49_003213"
     CDS             complement(16880..17914)
                     /gene="waaH"
                     /locus_tag="LSX49_003213"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HBL7169591.1"
                     /translation="MMNSTNKLSVIIPLYNAGDDFRTCMESLITQTWTALEIIIINDG
                     STDNSVEIAKHYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPTDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYKYYLH
                     NTSVSRLHRQGNKNLNYQRHYIKITRLLEKLNRNYADKITIYPEFHQQITYEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(18153..19178)
                     /gene="tdh"
                     /locus_tag="LSX49_003214"
     CDS             complement(18153..19178)
                     /gene="tdh"
                     /locus_tag="LSX49_003214"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBL7169592.1"
                     /translation="MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(19188..20384)
                     /gene="kbl"
                     /locus_tag="LSX49_003215"
     CDS             complement(19188..20384)
                     /gene="kbl"
                     /locus_tag="LSX49_003215"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBL7169593.1"
                     /translation="MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPELIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLSAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMHE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGK
                     QLGVIA"
     gene            20598..21530
                     /gene="rfaD"
                     /locus_tag="LSX49_003216"
     CDS             20598..21530
                     /gene="rfaD"
                     /locus_tag="LSX49_003216"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HBL7169594.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA"
     gene            21540..22586
                     /gene="rfaF"
                     /locus_tag="LSX49_003217"
     CDS             21540..22586
                     /gene="rfaF"
                     /locus_tag="LSX49_003217"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HBL7169595.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYVALAYDKGIMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNALLLQEEA"
     gene            22590..23549
                     /gene="rfaC"
                     /locus_tag="LSX49_003218"
     CDS             22590..23549
                     /gene="rfaC"
                     /locus_tag="LSX49_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HBL7169596.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSATL
                     VTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQMVCRAPRENLINLNSQAVLEKLSSL"
BASE COUNT         5902 a         6121 c         6111 g         5467 t
ORIGIN      
        1 gcgtaattat caacatattg gggttatgaa aaggaattca tcctatgagc atgaaaacac
       61 ttttaaacgt gttaacaata ttttcactag gtacattaac aggctgtgat tatattgaaa
      121 aagcgagtct gatcgatgat cttgccaaac agcaagagtt gcaaaaaagt aaaatagagg
      181 agcttgagaa acaacaagaa caatataaaa ataaagcaga actgtttgaa aaacaacaaa
      241 ataatatcac aaacagcacc agaatacttg ccagcattgt aaagacagtc aaagaaaaac
      301 aggacgaatt tgtcttcacc gaatttaacc cgctacaaac ccaatacttc attttaaata
      361 acggctcggt cggtttggca ggccgggtgc tggctattga tgcggttgaa aatggcagtg
      421 tcattcgtat ttcgctggtt aacttattaa gcgttcccgt atcaaatatt ggctttcatg
      481 cgacatgggg gaatgagaaa cccaccgatg ccaaagctct ggcgaaatgg caacaattac
      541 tattcaacac caccctgaat tccactctgc aattaatgcc tggtcaatgg caagacatta
      601 atctgacatt aaaaggcgtc tcgcctaata acctgaagta tctgaagttg tccatcaata
      661 tggctaatct tcagttcgac actgttcaac ctgctgaaac ccggcagcgg aaaaacaaaa
      721 aataaatgca gcttctgcgc ttatatcaag gaatagagag catcaataat gaacaaaata
      781 tttaaagtta tctggaatcc ggcgacaggc agttacaacg tcgccagcga aacggcgaag
      841 agccgtggca aaaagagcgg gcgcagtaag ctgttaattt ctgccttggt tgcaggtggg
      901 ctgttatcgt catttggggc actggctgat aactacgagg ggcagccagt ggattatggc
      961 aatggctcag caggtgacgg ctgggttgct atcggtaaaa attcaaaagc aaataccttt
     1021 gtcaatggct ctggtgcgag cactgcgcta ggttatgacg cgatagctga aggtgagtac
     1081 agctcagcta taggctcacg aactcatgcg attggtggtg catcaatggc ctttggggtt
     1141 agtgcacaag caataggtga cagaagtgtc gcgctgggtg catcttcagt agcaactggc
     1201 ggtcgttcga tggctcttgg tcgttacgca aagacgaatg gttttacatc tcttgctatt
     1261 ggggacaccg cccttgccga tggtgaaaaa actattgcgt taggaaatac ggctcaagct
     1321 tacgaaatta tgagcatcgc cctcggtgat catgctaatg cctcaaaaga atattcaatg
     1381 gcgctgggag caagtagcgt tgcatctgcg gctaacgcca ttgccgtagg ccgcgacagt
     1441 gctgctaacg gcacagacag ccttgcctta ggcagactat ctctcgccag cgcagcaaac
     1501 gcgattgcta tgggtgcaga gagcgaagct gctgaaaatg cgacggcgat tggctttaac
     1561 gcggatgcga tcgggaagtc cagcctggcg ctgggagaca acgccagcgc tggtgaaacc
     1621 aactccatcg ctataggtca aggcagcgag gcaagcaaac ttgattcaat tgcgctggga
     1681 agtaacagca ggtcagcggg tgagaacgcc attgcactgg gcaacaacag taatgcgggg
     1741 ggcaaaaaca gccttgcttt cggttttaac accaccgcaa atggtgataa cgcagtcgcc
     1801 attggtgcaa attcttccgc aggtgctgac aataccgtgt ctgtaggtag ctctagttta
     1861 aagcgcaaaa ttgtcaatat gggtaatggt gacatcaata atgtcagctc cgatgccatc
     1921 aatggatcac aactttatgc catcagtaag tctgtatccg acaggcttgg aggatatcat
     1981 gatgatcctg ataatgttat aaactctgac gggacgctta aagctcccac atattatcta
     2041 caaagtggcc aatacaataa cgtgggagag gctctccaga gcatcgacaa taacacgttg
     2101 cactgggaca gcaaaagtaa taaatacagt gccagccata ctgtctttaa tgcaaatggc
     2161 tcagttaaaa gcacctcggc gaaaaacatc attaccgacg tcgctgatgg cacgatttca
     2221 gccaccagtt ccgacgccgt taacggttcg cagttgtata atctgaaaca agatgccctg
     2281 ctatgggatg gcactgcgtt tagcgccaaa catggcacca gcaatactga cagcaaaatc
     2341 accaacgtac tggcaggcac agtatcttcc accagcaccg atgccattaa tggtacacaa
     2401 cttcaaagca ctgcaagcac cattacgtcc tatttgggcg gcggcgcggc aatgagtaat
     2461 gacggcgtat ttaccggtcc tcaatataat attggtggta agaattacac caatgttggc
     2521 gcagctctta ccgctctgga caatgacgcc ctgttgtggg atgcaaccgc taattcaaat
     2581 actggcgcat tcagtgctgc acacggaaca ctcaaaaccg ccagcaagat taccaacgtt
     2641 gcaaatggtg acatattagc caacagttat gatgctatta atggctcaca actttatagt
     2701 ttagctgatt catttacgtc ataccttggc ggtggtgctg atatcaacaa tgcgggtgtt
     2761 ctcatagccc cgacctatac tatcggttcg aaaacgtaca acaacgtagg tgatgccctt
     2821 aacgcgatta actcatcatt cagcacctca atcagtgatg ccctgctgtg ggattctaca
     2881 gcgaacaaat tcagcgccaa acacggtggt accaatagca ttattactaa cgttgcagac
     2941 ggtacaattt cctctaccag cagcgatgct gtaaatggct cgcaactcta tgacacgagc
     3001 aagtacattg ctgatgccct gggtggtgac gcagaagtta acgctgacgg caccatgact
     3061 gcaccgactt actctatcgc taatgaagat taccacagcg taggtgaagc cctggatgcg
     3121 ctcgatgata acgcgctgct gtgggatgaa gacgcaggtg cctacaacgc cagccatgat
     3181 ggcaatgcca gcaaaattac caacgttgcg gcaggtgatc tctccacaac cagtaccgat
     3241 gctgttaacg gttcccagtt aaacgcaacc aatattctgg ttacgcaaaa tagccaaatg
     3301 attaaccagc ttgccggtaa caccagcgaa acctacatcg aggaaaacgg tgcgggtatt
     3361 aactatgtac gtaccaacga caacggctta gcgttcaacg atgccagcgc ctcaggtatt
     3421 ggtgctacgg ctgtgggtta taactctgtt gccgaaggtg atagcagcgt ggccattggt
     3481 caaggtagca gcagctccgt tgataccggc attgccttgg gtagcagctc cgtttccagt
     3541 cgcgtgattg ttaaaggttc tcgtaacact agtgtaacgg aaaatggcgt agttatcggt
     3601 tatgacacca ctgacggtga gttgctcggt gcattgtcaa ttggtgatga cggtaaatac
     3661 cgtcaaatca tcaacgtcgc cgatggttcc gaagcccatg acgccgttac ggttcgccag
     3721 ctgcaaaatg ccattggtgc agtcgctacc acgccgacta aatacttcca cgctaactca
     3781 acggctgaag actcactggc agtcggtgaa gactcgctgg caatgggcgc gaaaaccatc
     3841 gttaatggta atgcgggtat tggtatcggc ctgaacacgc tggttctggc tgatgcgatc
     3901 aacggtattg ctatcggttc taacgcacgc gcaaatcatg ccgacagcat tgcaatgggt
     3961 aatggttctc agactacccg tggtgcgcag accaactaca ctgcctacaa catggacgcg
     4021 ccgcagaact ccgtgggtga gttctctgtc ggcagtgaag acggtcaacg tcagatcacc
     4081 aacgtcgcag cggggtcggc ggataccgat gcggtcaacg tgggtcaatt gaaagtaacg
     4141 gacgcgcagg tttcccagaa tacccagagc attactaacc tgaacactca ggtcactaat
     4201 ctggatactc gcgtgaccaa tatcgaaaac ggcattggcg atatcgtaac caccggtagc
     4261 actaagtact tcaagaccaa caccgatggc gcagatgcca acgcgcaggg taaagacagt
     4321 gttgcgattg gttctggttc cattgctgcc gctgacaaca gcgtcgcgct gggcacgggt
     4381 tccgtagcag acgaagaaaa tacgatctct gtgggttctt ctaccaacca gcgccgtatc
     4441 accaacgttg ctgccggtgt taatgccacc gatgcggtta acgtttcgca actgaagtct
     4501 tctgaagcag gcggcgttcg ctacgacacc aaagctgatg gctctatcga ctacagcaac
     4561 atcactctcg gtggtggtaa cggcggtacg actcgcatca gcaacgtctc cgctggcgtc
     4621 aacaacaacg acgcagtgaa ctatgcgcaa ctgaagcaaa gcgtgcagga aacgaagcaa
     4681 tacaccgatc agcgcatggt tgagatggat aacaaactgt ccaaaaccga aagcaagttg
     4741 agcggtggta tcgcttctgc aatggcgatg accggtctgc cgcaggctta cacgccgggt
     4801 gccagcatgg cctctattgg tggcggtact tacaacggtg aatcggctgt tgctttaggt
     4861 gtgtcgatgg tgagcgccaa tggtcgttgg gtctacaaat tacaaggtag taccaatagc
     4921 cagggtgaat actccgccgc actcggtgcc ggtattcagt ggtaatgatc cattaacgaa
     4981 tgggtaaacg ccacattgcc tgatgcgcta cgcttatcag gcctacgggg tgattcagca
     5041 cattcctgta ggtcggataa ggcgttcacg ccgcatccgg caagataagg cactccgggt
     5101 caacaatcta agggcaattc tctgatgagg attgcccttt tctttaccag acatctccca
     5161 ccacaagaat tggccctacc aattcttcgc ttatctgacc tctggttcac aattccccaa
     5221 ttaaaactca catcaatgtt gccaacacgt aacatttagt taaccattca ttgtcattac
     5281 ccctacacaa cacaattggc agtgccactt ttacacaacg tgtgacaaag agatgggcaa
     5341 cagactcatt acacggcgtg tgtggactgc aggagacctg caatgaatct ctggcaacaa
     5401 aactacgatc ccgccgggaa tatctggctt tccagcctga tagcatcgct tcccatcctg
     5461 tttttcttct ttgcgctgat taagctcaaa ctgaaaggat acgtcgccgc ctcatggacg
     5521 gtggcaatcg cccttgccgt ggctttgctg ttctataaaa tgccggtcgc taacgcgctg
     5581 gcctcggtgg tttatggctt cttctacggg ttgtggccca tcgcgtggat cattattgca
     5641 gcggtgttcg tctataagat ctcggtgaaa accgggcagt ttgacatcat ccgctcgtct
     5701 attctttcga taacccctga ccagcgcctg caaatgctga tcgtcggttt ctgtttcggc
     5761 gctttccttg aaggagccgc aggctttggc gcaccggtag caattaccgc cgcattgctg
     5821 gtcggcctgg gctttaaacc gctgtacgcc gccgggctgt gcctgattgt taacaccgcg
     5881 ccagtggcat ttggtgcgat gggtattccg attctggtcg ccgggcaggt aacaggcatc
     5941 gacagctttg agattggtca gatggtgggg cgtcagctgc cgtttatgac cattatcgtg
     6001 ctgttctgga tcatggcgat tatggacggc tggcgcggta tcaaagaaac ctggcctgcg
     6061 gtcgtggttg cgggcgggtc gtttgccatc gctcaatacc tcagctctaa ctttattggg
     6121 ccggaactgc cagacattat ctcttcgctg gtatcgctgc tctgtctgac actgttcctc
     6181 aaacgctggc aacccgtgcg cgtattccgc ttcggtgact taggggcgtc acaggttgat
     6241 atgacgctgg ctcacacagg ttacacggca ggtcaggtgc tgcgcgcctg gacaccgttc
     6301 ctgttcctga ccgccaccgt aacactgtgg agtatcccgc cgtttaaagc cctgttcact
     6361 tcaggcggtg cgctgtatga gtgggtgatc aacattccgg tgccgtacct cgataaactg
     6421 gttgcccgta tgccgccagt ggtcagcgaa gcgacagcgt atgccgccgt gtttaagttc
     6481 gactggttct ctgccaccgg taccgccatt ctgtttgctg ccctgctctc gattgtctgg
     6541 ctgaagatga aaccatctga cgctatcagc accttcggca gcacgctgaa agaactggct
     6601 ctgcctatct actccatcgg catggtgctg gcgttcgcct ttatctcgaa ctattccggt
     6661 ttgtcatcaa cactggcgct ggcactggcg cacaccggtc atgcattcac cttcttctcg
     6721 ccgttcctcg gctggcttgg ggtattcctg accgggtcgg atacgtcatc taatgctttg
     6781 tttgccgctt tgcaggctac cgccgcacaa caaattggcg tttctgacct gttgctggtt
     6841 gctgccaaca ccaccggtgg tgtcaccggc aaaatgatct ctccgcaatc tatcgctatc
     6901 gcctgtgcgg cggtaggcct ggtgggcaaa gagtctgatt tgttccgctt tactgtcaaa
     6961 cacagcctga tcttcacctg tatggtgggc gtgatcacca cgcttcaggc ctatgtctta
     7021 acgtggatga ttccttaatg attgttttac ccagacgcct gtcagacgag gttgccgatc
     7081 gtgtgcgggc gctgattgat gaaaaaaacc tggaagcggg catgaagttg cccgctgaac
     7141 gtcaactggc gatgcaactc ggcgtgtcga gaaattcact gcgcgaggcg ctggcgaaac
     7201 tggtaagcga aggtgtgctg ctcagtcgac gtggcggcgg gacgtttatt cgctggcgtc
     7261 atgacacatg gtcggagcaa aacatcgtcc agccgctgaa aacgctgatg gccgatgatc
     7321 cggattacag tttcgatatt ctggaagccc gctacgccat tgaagccagc accgcatggc
     7381 atgcagcaat gcgcgccaca cctggcgaaa aagaaaagat tcagctttgc tttgaagcaa
     7441 cgctaagtga agacccggat ctcgcctcac aagcggacgt tcgttttcat ctggcgattg
     7501 ccgaagcttc acataacatt gtgttgctgc aaaccatgcg cggtttcttc gatgtcctgc
     7561 aatcctctgt gaagcatagc cgccagcgga tgtacctggt acccccggtt ttttctcagc
     7621 tgaccgaaca acatcaggcg gtcattgacg ccatttttgt cggtgatgct gacggggcgc
     7681 gtaaagcaat gatggcgcac cttagctttg ttcacaccac catgaaacga ttcgatgaag
     7741 atcaggctcg ccatgcacga attacccgcc tgcctggtga ccataatgag cattcgaggg
     7801 agaaaaacgc atgattattt ccgcagccag cgattatcgc gccgcagcgc aacgcattct
     7861 gccgccgttc ctgtttcact atatggatgg gggggcatat tctgaataca ccctacgccg
     7921 caacgtggaa gatttgtcag aagtggcgct gcgccagcgt attctgaaaa acatgtctga
     7981 cttaagcctg gaaacgacgc tgtttaatga gaaattgtcg atgccggtgg cgctaggtcc
     8041 ggtaggtttg tgtggcatgt atgcgcgacg cggcgaagtt caggctgcca aagccgcgga
     8101 tgcgcatggc attccgttta ctctctcgac ggtttccgtt tgcccgattg aagaagtcgc
     8161 tccagctatc aaacgtccga tgtggttcca gctttatgtg ctgcgcgatc gcggctttat
     8221 gcgtaacgca ctggagcgag caaaagccgc gggttgttcg acgctggttt tcaccgtgga
     8281 tatgccgaca ccgggagcgc gttatcgtga tgcgcattct gggatgagcg gcccgaacgc
     8341 ggcaatgcgc cgctatttgc aggcggtgac gcatccgcaa tgggcgtggg atgtgggcct
     8401 gaacggtcgt ccgcatgatt taggtaatat ctcggcttac ctcggcaaac cgaccggact
     8461 ggaagattac atcggctggc tggggaataa cttcgatccg tccatctcat ggaaagacct
     8521 tgagtggatc cgcgatttct gggatggccc gatggtgatc aaagggatcc tcgacccaga
     8581 agatgcgcgc gatgcagtac gttttggtgc tgatggaatt gtggtttcta accacggtgg
     8641 ccgccagctg gacggtgtgc tctcttctgc ccgtgcactg cctgctattg cagatgccgt
     8701 gaaaggtgat atcgccattc tggcagatag cggaatacgt aacgggcttg atgtcgtgcg
     8761 tatgattgcg ctcggtgccg acacagtact gctgggtcgt gctttcctgt atgcgctggc
     8821 aacagcgggc caggcgggtg tagctaacct gctaaatctg atcgaaaaag agatgaaagt
     8881 ggcaatgacg ctgactggcg cgaaatcgat tagcgaaatt acgcaagatt cgctggtgca
     8941 ggggctgggt aaagagttgc cggcggcatt ggctccgatg gcgaaaggga atgcagctta
     9001 agggttagac gaatatctgc tatcctgccc ccgcactaag ggggcagtat gctaaacatc
     9061 gtactttacg aaccagaaat tccgccaaat actggcaaca tcatccgtct ttgcgctaat
     9121 accggctttc gtctgcatat catcgaaccg atgggatttg cctgggacga taagcgcctg
     9181 cgccgcgcgg ggctggacta tcacgagttt accgccgtta cgcgtcatca tgactatcgc
     9241 gcgtttctcg aagcagaaaa tccccagcgt ctgtttgccc tcaccacgaa aggtacgcct
     9301 gctcacagcg ccgtaagcta tcaggatggc gattatctga tgttcggccc ggaaacacgc
     9361 ggcctgccag cgagcattct tgatgccctg cccgctgaac aaaaaattcg tattccaatg
     9421 gtgccggaca gccgcagcat gaacctgtcc aatgcggtgt cggtcgtggt gtatgaagcc
     9481 tggcggcagt tggggtatcc gggagcggta ttgagagatt agttactgta ggccggatag
     9541 atgattacat cgcatccggc acgatcacag gacatcagat cccatcacca tactcaaacg
     9601 tatggttaat gccgttgaaa tgctgatcca tatccattga cggtttatcg ctatccggct
     9661 tgccgacaat gcgtgccgga acgccagcgg cagtagtgtg cggcggcacc ggttgcagca
     9721 ccacggaacc tgcgccaatc ttcgcgccgc gcccaacttc aatattgccg agaattttcg
     9781 cgcccgcgcc aatcatcaca ccttcacgaa ttttcgggtg acggtcgcca ccagatttac
     9841 ccgtaccgcc aagcgtcaca gattgcagaa tcgatacgtc gttttcaatc accgccgttt
     9901 caccaacgac gatgcctgtc gcgtggtcga gcatgatacc gcgaccaatt tttgctgccg
     9961 ggtgaatatc aacctggaac gtcacagaaa cctggttttg cagaaaaata gccagtgcgc
    10021 gacgcccctg attccacaac cagtgaccga tgcgatacgc ctgcaaagca tgaaaaccct
    10081 tcaggtatag caacggggtt gagtatttat ccaccgccgg gtcacgggta cgcaccgcct
    10141 gaatatcaca ggccgcagag gcgatcattt ccgggtcggc ggcgtaggct tcttccacca
    10201 cttcacggat agcaatagcc ggcataatgg gcgatgacag cttgttcgcc agcatgtagc
    10261 tcagtgcact gccaaggttt tcgtgcttga gtagcgtcgc gtggtaaaaa ctggccagca
    10321 ttggctcaca gtccgccagc gttctggctt cagctttaat attgttccag acaatttcca
    10381 gttcttcaca cgacattgct tactccacac gatgagataa tgaccgaccc gttctgcgcg
    10441 ggccgggtca tagtggtaac aaaggttccc tgggtttagt ggctgctgcg ctcgtccttg
    10501 cgtgcacgac ctagtaaagt caatgctgcc tcgcgcgcgt tttttccgca atataatact
    10561 tgataaattt cctcggttat tggcatttca acgccgaagc gatgcgccag ttcgcggact
    10621 tctttcgtat tgcggtagcc ttccaccact tgaccaattt tctcctgcgc gctttgtaca
    10681 tccatgccct gaccgagcat catgccaaaa cggcggttac gcgactggtt gtcggtacag
    10741 gtaagcacca gatcgcccag ccccgccatg cccataaagg tggcaggatc ggcacccagc
    10801 gccgcgccaa gacgcgacat ctcagccagc ccacgagtga tcagcgccgt acgcgcattc
    10861 gcaccaaaac cgataccgtc ggacatcccc gcgccaatgg caatgacgtt tttcaccgcg
    10921 ccgccaagct gcacaccgat gaaatccggg ttgctgtaaa cgcggaaact tttgccacag
    10981 tgcagcaatt gctggaggtc atcggcaaag gtctggtccg tcgaggccag cgaaatggcc
    11041 gtcggtaaac ctgccgccag ttctttcgca aacgttgggc cagagataac cgccagcgga
    11101 atttgatcgc ctaaggcctc acgcgccacg tcctgtaaca gacgtccggt ttctgcttcc
    11161 agccctttgg ttgcccacac cagacgcgca tcaggacgca tcagcggttt aatctggcgc
    11221 agcacttcac caaagacatg gctgggtacg acgacgagaa tattacggct ggctgccagc
    11281 gcagtggcga gatcgctttc aagatggagc gtatcgggaa aaggcacatc ggggagaaac
    11341 gcggcgttac agcggtcgcg ttcaagcgtt gcgatatgtt cagggtcatg gccccagagg
    11401 acaacctcgt ggccatttct tgccagggtg atggcaagag cggtgccgta cgagccggca
    11461 ccgatcacag tcattgaagc attacgttgg ttcatcaggc atcctgatgt tcttcagtac
    11521 cttcgccagc ctgctgctgc aaatagttca tgaacagcgc atcgaagtta accggcgcaa
    11581 ggttcagttg cgggaatgta ccgcgggata ccatgctggt gatgcactca cgagcatacg
    11641 ggaacagaat gttcgggcag tatgcgccca ggcaatgtgc catctgggtg ccttcgatac
    11701 ccgcgatgga gaaaataccg ccctgctgaa cttcacacag gaacgcggtt tcttcgccca
    11761 gggaggccgt tacggtaaca cgcagtacca cttcgtaaac gtcatctgcc agttgagtag
    11821 atgccgtatc cagatcaagt ttaacttctg gttgccaatc tttctggaaa acgtgcggcg
    11881 cgttcggcgc ttcgaaagaa atatccttgg tataaatacg ttggatctgg aaagtcattt
    11941 cggtgttgtt ttgttctgac atgtgtagaa aacccttaag tgttgtcctt aaaatactgc
    12001 gcaatgtaat gccaacgttc acacgttatt tcagcagggg atccagtcca ccacgtgcat
    12061 ccaatgcata caagtcatca cagccaccaa tgtgctgtgc gtcaataaaa atctgtggaa
    12121 ccgtggtgcg accgctgcgt ttgatcatct cttcacgctt agcggcattg ccatcgatcg
    12181 gcaactcctg aaaactcacg cccttgctgc ttagcagtgc ttttgcacga tggcaatacg
    12241 ggcaggtttc tttggtatag atttcaacat tggccataaa ttagctcctg ttttttaccc
    12301 tgaaatttca tgttgcaggg cggcagcaaa atggagtgtc cccagaagct tatatcaata
    12361 agtcgctggg ggcctaattg cagctaacgg cctgcatcat gaaagacgac aggtaaatta
    12421 tttgccgcgc accaaaggca agttttcgcc agcccagcca gcgacgcctt ctttcagtac
    12481 gaatacttgt gcaaaaccag ctttcgtcag cgcgtttgca ggctcctggc actgcatgcc
    12541 agaaccatct accacgataa ccggtttgtc tttgtgcttc tcaagctcac caacattgtt
    12601 ggctttgatt tcgctcggca acaggttgat agaacctgcg atatggcctt tacggaagtc
    12661 atcacgctga cgtaaatcca caaccacagc gtcttctttg ttgatcagac gcgtagcttc
    12721 accacgagta atcaccttca ctttcgaggt caggctctta aacgtagtca caagaaccgc
    12781 caccagtaac gcgatccagg cgatactcag tatgggatga cggccaacaa attgcataat
    12841 ttcttgcatg gggggtaaca actcccgacg tagtgattaa aaaaccagga aaggagtata
    12901 cctgcgcagt gcggcaaata cagccagcgc gttaactgga atgcaatttt gcggggcgct
    12961 acgaaaaaaa agcgtaaatc tggcatctgc ttgccgcgag cggtcgtata ttttgatctt
    13021 cagaggctat tttatcgatt cagctgtagt aaaattacgc aaattttgac tcttgagtat
    13081 gaggttgtcg caatgtcggt ttctaaaaaa cctatggtac tggtgattct ggatggctat
    13141 ggctatcgcg aagaacagca ggataacgcc atttttagtg ctaaaacccc ggtaatggat
    13201 gcactgtggg ccaatcgtcc gcataccctg atcgacgctt ccggtctgga agtcggtctg
    13261 cctgaccgtc agatgggtaa ctccgaagta ggccacgtta acctgggtgc aggccgcatc
    13321 gtgtatcagg acctgactcg tctggacgtt gaaatcaaag atcgcacttt ctttgctaat
    13381 ccggtgttga ctggtgcggt agataaagcg aaaaacgcag gcaaagcagt acacattatg
    13441 ggtctgctct ccgcaggtgg tgtacacagc cacgaagatc acatcatggc gatggtagaa
    13501 ctggcagctg aacgcggcgc agaaaaaatc tacctacacg cattccttga cggtcgcgac
    13561 actccgccgc gcagtgctga atcctcgctg aaaaaattcg aagagaaatt tgccgcgctg
    13621 ggtaaaggcc gcgtagcgtc catcattggt cgttactacg cgatggaccg cgataaccgt
    13681 tgggatcgcg ttgaaaaagc ttatgacctg ctgactctgg cgcaaggtga gttccaggcc
    13741 gataccgccg ttgccggttt gcaggctgct tatgctcgcg acgaaaacga cgagttcgtg
    13801 aaagcgaccg ttattcgtgc agaaggtcag ccagatgcgg caatggaaga cggcgatgcg
    13861 ctgattttca tgaacttccg tgctgaccgc gcacgtgaaa tcactcgtgc attcgtaaat
    13921 gccgattttg acggcttcgc gcgtaagaaa gtggttaacg tcgatttcgt gatgctgacc
    13981 gaatacgctg ccgacatcaa aaccgcagtg gcttacccac ccgcttccct ggttaacacc
    14041 ttcggcgagt ggatggcgaa aaacgacaaa actcagctgc gtatttccga aaccgaaaaa
    14101 tatgcccacg ttactttctt cttcaacggt ggcgtagaag agtcgttcaa aggcgaagat
    14161 cgcattctga tcaactcacc gaaagtggct acctacgatc tgcaaccgga aatgagctcc
    14221 gcagagctga ccgaaaaact ggttgcggca atcaagagcg gcaaatacga caccattatc
    14281 tgtaactatc cgaacggcga catggtaggt cacaccgggg tgatggaagc ggcggttaaa
    14341 gcggttgaag cgctggatca ctgcgtggaa gaagtcgcga aagcggttga gtccgtgggt
    14401 ggacaactgc tgatcaccgc tgaccacggt aacgctgaac agatgcgcga tccggcaacg
    14461 ggtcaggcac acacagcaca caccaacctg ccagttccgc tgatttacgt tggtgataag
    14521 aacgtgaaag cggttgaagg cggcaaactt tctgacatcg cgccgaccat gttgtcgctg
    14581 atgggtatgg aaatcccgca agagatgact ggtaagccgc tgttcatcgt ggaataatcc
    14641 ctccccatga ggggaaaggc gattaatacc atgacacggg ccgtgaaacc gcgcaggttt
    14701 gcaatcaggc ccatcatcta cgccagcgtt ctgagcgctg gcgtattgtt gtgcgccttt
    14761 tccgcccacg cggatgagcg tgaccaactc aaatccattc aggctgacat cgccgcgaaa
    14821 gagcgcgcgg tacgccaaaa gcaacaacaa cgcgcaagcc tgctcgcaca attgaaaaag
    14881 caggaagaag cgatctctga agccacccgt aaactgcgcg aaacgcaaaa cacgcttaat
    14941 caactgaata aacagattga tgagatgaac gcgtcgattg ccaaactgga gcagcaaaaa
    15001 gccgcccagg agcgcagcct cgccgcgcaa ctggatgccg cgtttcgtca gggtgaacat
    15061 accggtattc agctgattct cagcggtgaa gaaagccagc gtgggcagcg gttacaggct
    15121 tatttcggct atctcaacca ggcgcgacaa gaaaccattg ctcagttgaa acaaacgcgt
    15181 gaagaagtcg ctatgcagcg tgccgaactg gaagagaaac aaagcgagca acaaacgctt
    15241 ttatatgagc agcgcgccca acaggcgaag ctgacccagg cgttgagcga gcgtaaaaag
    15301 acgctggcag ggctggagtc ttccatccag caaggtcagc aacagttgag cgagctgcgc
    15361 gccaacgaat cccgcctgcg taacagcatt gcccgtgcgg aagccgcggc gaaagcgcgt
    15421 gctgaacgtg aagcgcgcga agcccaggcg gttcgcgacc gccagaaaga agcgacgcgc
    15481 aaaggcacca cctacaagcc gaccgaaagc gaaaaatcgc tgatgtcccg taccggtggt
    15541 ctgggcgcac cgcgcggtca ggcattctgg ccggttcgcg ggccaacgct gcatcgctat
    15601 ggcgagcagc tacagggtga attacgctgg aaagggatgg tgattggtgc ctctgaaggt
    15661 actgaagtta aagcgattgc cgacggccgg gtgattctgg ctgactggct gcaaggctac
    15721 ggtctggtgg tggtggttga gcatggtaaa ggcgacatga gtctttacgg ctataatcag
    15781 agcgcactgg tgagcgttgg ttcgcaggtt cgcgcgggcc agccaattgc actggtgggc
    15841 agcagtggcg gtcagggtcg gccttcactc tatttcgaaa ttcgccgcca gggtcaggcg
    15901 gtcaatccac agccgtggtt gggaagataa gttttgtttc catttcgtcg taacgttctt
    15961 gcatttgccg ctctgttggc gctctcctcc cccgtaattg ctggcaaact tgccatcgtc
    16021 attgatgatt ttgggtatcg cccgcacaac gaaaaccagg tgctggcgat gccttccgct
    16081 atctccgtcg ctgtattacc cgattcaccg cacgccagag agatggcgac caaagcacat
    16141 aacagcggtc acgaagtgtt gattcatcta ccgatggcac cactgagtaa acagccgctg
    16201 gagaaaaata cgctacgccc ggagatgagc agcgacgaaa ttgagcgcat tattcgtagt
    16261 gcggtcaata acgtgcccta tgccgtgggg atcaacaacc acatgggcag caagatgacc
    16321 tctaacctgt ttggtatgca gaaagtgatg caggcgctgg agcgttacaa tctttacttt
    16381 ctcgacagcg taaccatcgg taatacccag gcgatgcgcg ccgcgcaagg cactggcgtg
    16441 aaggtgatca aacggaaggt gttcctcgac gattcgcaga acgaagcgga catccgtgtg
    16501 caattcaatc gcgcaattga cctagcgcgt cgcaacggtt caaccattgc cattgggcat
    16561 cctcaccctt caacggtacg cgtgctacaa cagctggttt ataacctgcc gccagacatt
    16621 acgctggtga aagccagcag cttgctgaat gaaccgcagg ttgatacgtc tacaccgccg
    16681 aaaaacactg tgcccgacac accgcgtaat ccgttccgtg gcgtgaagct gtgcaaaccg
    16741 aagaagccgc tggaacctgt ttatgctaat cgcttctttg aagtattaag cgaaagcatc
    16801 agccagagca cgctgatcgt ttacttccag catcagtggc aaggctgggg caaacagccc
    16861 gaagcggcaa aacttaacgc tagcgcaaat taaaggcgct acgcgtaatg cgatggtgcg
    16921 accgcgtttt gtcgcgccat tgccataagc ggaaagacca cagtaacgcc tggtaaccca
    16981 ccttcacgct gcggacattg gtaatcaggc gcttatacat accggaagta aatatctcgg
    17041 caatcatccg ttggcgggta agaatatccg gctctttgcg caccgcatgg caaacacgca
    17101 atgcttcgta agttatttgc tgatgaaatt ccggataaat cgtaattttg tcagcataat
    17161 ttcgatttaa tttctccagc aggcgggtaa tcttaatata gtgacgttga taattaaggt
    17221 ttttattccc ttgtctatgc aaccgactca ctgacgtatt atgcagataa tatttatata
    17281 atgattgctc ggtatatcgc gcacgcagcg cgttaaacat aaattctgtt gtccagacaa
    17341 tatcctgatg atgtaatccg gcaataaatt taatgttatt tttaacaata acatcgcggc
    17401 gataaacccc catccagacc acgtgtgtcc aacggcggga agaaagtccc atccgcagcc
    17461 agtccggacc ggttaataca ccggttgagc gaaggcgatc ggtggggatg gattgccagg
    17521 tttcacccgt ttcacgaaaa caccaatcag cgttgcactg cgccacgtcg aggtcatcct
    17581 ctaacgccat ggtcatcagc gtttcgtaca tggtgggata gacctcatcg tcagcatcga
    17641 caaaagcgac atattttccc gttgccactt caatcccacg attacgcgcc accgatgcgc
    17701 cagcattcgc ctgatgcaac aaacgaacgt gcggatagtt ttctgcgtaa tgctttgcta
    17761 tttcaacaga attatccgtt gaaccatcgt taataataat gatttccaga gcagtccatg
    17821 tttgcgtaat taaagattcc atacaagtgc ggaaatcatc gcccgcatta tataacggga
    17881 taataacact aagtttattg gtgctgttca tcataaatta ccgacgacct ctgaagttat
    17941 cctgacgttt tacaggcttt gtattaagaa actattaagc ctgtgagata ttatttttac
    18001 cggtgagaga gtcacttcag ggtagagaga taatgagagc agctatataa gagatcagtg
    18061 caattacgaa ctctttatta cactgacagg attttacata tttaacggat tatcctcagg
    18121 caaaagggct ggaataccag cccttgttcg tgttaatccc agctcagaat aactttcccg
    18181 gactggcccg aacgcatagc gtcaaagccc ttctggaaat catcgataga gaaacgatgg
    18241 gtaatgatcg gcgagagatc gaggccagac tgaatcagcg ccgccatctt gtaccaggtt
    18301 tcaaacatct cacgaccgta aataccttta atgaacaagc ctttaaagat tactttggtc
    18361 cagtcgatag acatatcgga cggtggaata cccagcatcg caatacgacc gccgtggttc
    18421 atggtgtcga gcatggtacg aaacgctggc ggcgcaccgg acatttccag accgacatca
    18481 aagccttcgg tcatgcccag ttctgccatc acatcattaa ggttttcttt agcgacgtta
    18541 accgcacggg tgatacccat tttgcgtgcc agctcaaggc ggtattcgtt aacatcagtg
    18601 atcaccacat tgcgtgcacc aacgtgtttc gccaccgccg cagccataat acctatcgga
    18661 cctgcaccag agaccagcac atcctcgcca accagatcga acgacagcgc ggtatgcacg
    18721 gcgttaccga agggatcaaa aatggaagcc aggtcgtcgg agatattgtc tgggattttg
    18781 aaggcgttga acgccggaat caccagatac tcggcgaagc agcccggacg gttaacaccg
    18841 acgccgatcg tgttgcggca cagatgggta cgaccgccac gacagttgcg acagtgaccg
    18901 caggtgatat ggccttcgcc agaaacgcga tcgccaatct tgaagccttt cacttcctga
    18961 ccaataccta ccacttcacc gacatattca tggcccacga ccatcggcac cgggatggtt
    19021 ttttgcgacc actcatccca gttatagatg tgaacgtcag tcccgcagat ggctgtttta
    19081 cggattttaa tcagcagatc gttatgcccg agttccggta caggaacgtc ggtcatccag
    19141 atgccctctt ccgctttcag tttggataac gctttcatct cacaccctca ggcgataacg
    19201 cccagttgtt taccaatacg cgtgaatgct tctactgcac gcgtaatttg ctcaggggta
    19261 tgcgccgcag acatctgggt acgaatacgc gcctgacctt taggaacgac cggatagaag
    19321 aaaccggtga cgtaaatgcc ctctttttgc agttcacggg caaatttttg cgccactaca
    19381 gcatcgccaa gcatgaccgg aataatggcg tgatcggcac ccgccagggt aaagcccgcc
    19441 gccgacatct gctcacggaa ctgacgcgcg ttcgcccaca gacggtcacg aagctcactg
    19501 cccgcttcga ccatctccag cactttaatg gaagcagcca caatggcagg tgccagtgag
    19561 ttggagaaca ggtaaggacg agaacgctga cgcagccact caaccacttc tttacgcgct
    19621 gcggtgtaac caccagaagc cccgcccaac gctttaccaa gcgtaccggt gataatatcg
    19681 acccgcccca tcacatcgca gtattcatgg gaaccacgac cattttcacc gacaaaaccg
    19741 accgcgtggg agtcgtctac catcaccagg gcatcgtatt tatctgccag atcgcaaacg
    19801 cccttcaggt tggcaatcac gccgtccatc gagaacacac catcggtggc aatcagcaca
    19861 tgacgcgcac cggcttcacg cgcttctttc agacgagctt ccagctcatg catatcgttg
    19921 ttggcataac gatagcgttt agctttacac agacgcacac catcaataat agacgcgtgg
    19981 ttcagtgcgt cggagataat ggcgtcctcc gcgctcagaa gcgtttcaaa caggccgccg
    20041 ttagcatcaa agcaggaaga gtagagaatc gcatcttcca tccccaggaa tgccgccagt
    20101 ttttgttcaa gctctttatg gctatcctgg gtgccgcaga taaagcgcac cgaagccatc
    20161 ccaaaaccat gagagtccat tcccgctttt gccgccgcaa tcagctctgg atgatttgcc
    20221 agtccgagat agttattggc gcaaaagtta ataacgtggc ttccatcagc cacagtgata
    20281 tctgcttgct gcgcagacgt aataatgcgc tcttctttaa acaacccttc cgcccgtgcg
    20341 gtttccagat cgttggttaa ctgctgataa aattctccac gcattgcgat tctccagaca
    20401 gggcaaattc cagcacatat tacccaaact tctaggtcgc gacgagatga cgcgttaaca
    20461 cttctgcaaa attcaggata aataacgtcc atcaatctca cttttggcga atggctgaag
    20521 ccaacgccgt gtagtgatat gatagaagta ttcgtgtctg agattgtctc tgactccata
    20581 attcgaaggt tacagttatg atcatcgtta ccggcggcgc gggctttatc ggcagcaaca
    20641 tcgttaaggc cctgaatgat aaaggcatca ccgatattct ggtggtggac aacctgaaag
    20701 acggcaccaa gtttgtgaac ctggtggatc tggatatcgc ggactatatg gataaggaag
    20761 acttcctgat ccagattatg gctggcgaag agttcggcga tgtcgaagcg attttccacg
    20821 aaggcgcgtg ctcttccacc accgagtggg acggcaagta tatgatggat aacaactatc
    20881 aatactccaa agagctgctg cactactgtc tggagcgcga aatcccgttc ctgtatgcct
    20941 cttccgcagc cacttacggt ggacgcacct ccgactttat tgaatcccgc gaatatgaaa
    21001 aaccgttgaa tgtctacggt tactcaaaat tcctgtttga tgaatatgtt cgccaaatcc
    21061 tgcctgaagc gaactcgcag attgttggct tccgttattt caacgtttat ggacctcgtg
    21121 aaggccataa aggcagtatg gcgagcgtcg ctttccatct caacacccag cttaataacg
    21181 gtgaatcacc gaagctgttc gaaggtagcg agaactttaa acgtgacttc gtctatgtgg
    21241 gcgacgtggc agatgtaaac ctgtggttcc tggaaaatgg cgtttccggc atcttcaacc
    21301 tcggcaccgg tcgtgcggaa tccttccagg cagtagcaga tgctacgctt gcttatcaca
    21361 agaaaggcca aatcgaatac attccgttcc cggataaact gaaaggccgc taccaggcgt
    21421 tcactcaggc agatctgacg aatctgcgcg cggcgggtta cgataaaccg ttcaaaaccg
    21481 ttgccgaagg cgtaacggaa tacatggcct ggctgaatcg tgacgcataa gagctctgca
    21541 tgaaaatact ggtgatcggc ccgtcttggg ttggcgacat gatgatgtcg caaagtctct
    21601 atcgcacgct ccaggcgcgc tatccccagg cgataatcga cgtgatggca ccggcatggt
    21661 gccgtccatt attatcgcgg atgccggaag ttaacgaagc tatccctatg cctctcggtc
    21721 acggagcgct ggaaatcggc gaacgccgca aactgggtca tagcctgcgt gaaaagcgct
    21781 acgaccgcgc ctacgtctta cctaactcct tcaaatccgc attagtgcct ttcttcgcag
    21841 gtattcctca tcgcaccggc tggcgcggcg agatgcgcta cggtttactc aacgatgtac
    21901 gcgtgctcga taaagaagcc tggccgctaa tggtggaacg ctatgtcgcg ctggcctatg
    21961 acaaaggcat tatgcgtaca gcacaagatc tgccgcagcc attgttatgg ccgcagttgc
    22021 aggtgagcga aggtgaaaaa tcatatacct gtaatcaatt ttcgctctca tcagaacgtc
    22081 cgatgattgg tttttgcccg ggtgcggagt ttggtccggc aaaacgctgg ccacactacc
    22141 actatgcgga gctggcaaag cagctgattg atgaaggtta tcaggtggtt ctgtttggct
    22201 cggcgaaaga tcatgaagcg ggcaatgaga ttcttgccgc tttgaatacc gagcagcagg
    22261 catggtgtcg gaacctggcg ggggaaacac agcttgatca agcggttatc ctgattgcag
    22321 cctgtaaagc cattgttact aacgattctg gcctgatgca cgttgcggcg gcgctcaatc
    22381 gtccgctggt tgccctgtat ggtccgagta gcccggactt cacaccaccg ctatcccata
    22441 aagcacgcgt gatccgcctg attaccggct atcacaaagt gcgtaaaggt gacgcggcgg
    22501 agggttatca ccagagcttg atcgacatta ctccccagcg cgtactggaa gaactcaacg
    22561 cgctattgtt acaagaggaa gcctgacgga tgcgggttct gatcgttaaa acatcgtcga
    22621 tgggcgatgt tctccatacg ctgcccgcac tcactgatgc ccagcaggca atcccaggga
    22681 ttaagtttga ctgggtggtg gaagaagggt tcgcacagat tccttcctgg cacgctgccg
    22741 ttgagcgagt tattcctgtg gcaatacgtc gctggcgtaa agcctggttc tcggccccca
    22801 taaaagctga acgcaaagcg tttcgtgaag cgctacaagc agagaactat gacgcagtta
    22861 tcgacgctca ggggctggta aaaagcgcga cgctggtgac gcgtctggcg catggcgtaa
    22921 agcatggaat ggactggcaa accgctcgcg aaccgttagc cagcctgttt tacaatcgta
    22981 aacatcatat tgcaaaacag cagcacgccg tagaacgcac ccgcgaactg tttgccaaaa
    23041 gtctgggcta tagcaaacca caaacccagg gcgattatgc tatcgcacag catttcctga
    23101 cgaacctgcc tacagatgct ggcgaatatg ccgtatttct tcatgcaaca acccgagatg
    23161 ataaacactg gccggaagaa cactggcgag aattgattgg tttactggct gattcaggaa
    23221 tacggattaa acttccgtgg ggcgcgccgc atgaggaaga acgggcgaaa cgactggcgg
    23281 aaggatttgc ttatgttgaa gtattgccga agatgagtct ggaaggcgtt gcccgcgtac
    23341 tggccggggc taaatttgta gtgtcggtgg atacggggtt aagccattta acggcggcac
    23401 tggatagacc caatatcacg gtttatggac ctaccgatcc gggattaatt ggtgggtatg
    23461 ggaagaatca gatggtttgt agggctccaa gagaaaattt aattaacctc aacagtcaag
    23521 cagttttgga aaagttatca tcattataaa ggtaaaacat gctaacatcc tttaaacttc
    23581 attcattgaa accttactct c
//
LOCUS       DAFGPF010000073        23291 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFGPF010000073 DAFGPF010000000
VERSION     DAFGPF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23291
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.073"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(22..738)
                     /locus_tag="LSX49_003219"
     CDS             complement(22..738)
                     /locus_tag="LSX49_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBL7169597.1"
                     /translation="MLQDVFESEEFAATLVLTPQQESHYLQAYLPLVRKVVRQLAPQC
                     NCIIDRQDMEQTALMGLLNAIRRYGLPDEGFAGYAVHRIRGAILDELRALDWRPRQLR
                     QKYHQMKDLIRETRKKLGHEPEWQELAEEGISHEDYLEYQQLEGAETLASLDELLNGE
                     GPGIPLAGRELEDQFVTQQMLQHALSQLSEKEQLILSMYYQHEMNLKEIALVLGLTEA
                     RICQLNKQIAQKIRDFVYPN"
     gene            complement(758..1225)
                     /locus_tag="LSX49_003220"
     CDS             complement(758..1225)
                     /locus_tag="LSX49_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBL7169598.1"
                     /translation="MKKIVVAGVVSAVLALVVGAGAGWSVWHHYAGKGKPTTAAQTES
                     VEALDESKSVFVTLPETIVTLHDNNGADHYLSAELVMVVASDKEAEKIKHQEPLYQSI
                     AVECLTEMKFEDLRGMKISAIRKLISDALKKDLQRRKMTAPYKDLLVKKVVFQ"
     gene            complement(1233..2294)
                     /locus_tag="LSX49_003221"
     CDS             complement(1233..2294)
                     /locus_tag="LSX49_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBL7169599.1"
                     /translation="MNPALLATLGTLAETASLKADILPPVSGENAPVFTLPKMVVAAV
                     AERVHSAKTSQQQATRPQENDPVAMQALMALLLPQPAAPHQDTPQPRNVATSPVIQQL
                     TKAVVQNAPQRPTQQQELTSLPPQLQELIGQLPQAKPEQQARLATYASEDLHAIAPTQ
                     PRVSTPPARPKPELTRVTARPQVERKTEKVPDSEPVIARAVLQVKTPELVSDHQEIVA
                     KPATLSMDELGEKLTTLLKDQIHFQLNKQQQISTIRLDPPSLGKLEIAVQLDNGKLTV
                     HIGANQSEVCRALQQFSDDLRQHLTAQNFMEVNVQVSSEGQSQQQQQSGHQQEEVSAA
                     LQLDDAPQFQQNESVLIKV"
     gene            complement(2291..2602)
                     /locus_tag="LSX49_003222"
     CDS             complement(2291..2602)
                     /locus_tag="LSX49_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBL7169600.1"
                     /translation="MEKQRRQLFALVEAMNDALDKQRWRRLPALYQQLMRQFHDYAAA
                     ETDAAQLDAVKAQLYGAFNALIKRREQRAEVLKARMEQHQRHQEGVLAYSIVNLLSEK
                     S"
     gene            complement(2607..2999)
                     /gene="fliS"
                     /locus_tag="LSX49_003223"
     CDS             complement(2607..2999)
                     /gene="fliS"
                     /locus_tag="LSX49_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBL7169601.1"
                     /translation="MYQVQDGYSQYKEIDLAARTAAASPLELVLVLFSGLMDELERAR
                     SHIEGRRFEKKAQSINKCIDILNALTSSLEFETGGELVVNLSRLYDHCVYRLYEASGE
                     LSAEKIDEVMLILSNLREGWEGLSGKLG"
     gene            complement(3022..4338)
                     /gene="fliD"
                     /locus_tag="LSX49_003224"
     CDS             complement(3022..4338)
                     /gene="fliD"
                     /locus_tag="LSX49_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBL7169602.1"
                     /translation="MINPRTIAQEIAYADVATQATNLQEKQSELDAESSGLDSLSSAL
                     SDFQSAVDALNSDTDGPVTFAATSNNDSATVSANSQAQAGSYSFFVEQLAQGQQTTFS
                     MGDDAFSATGTFELTMGDSTMDIDLSAADQNGDGDGFIDASELVNAINDSDDNPGVSA
                     ALVKTDGTTTIMLTSDSTGAQSAFSVSVTGHDASNDSTSAPVATDVSSAQDAIIHLGS
                     ASGPAITNSSNTFDDVIPGVTMTFTEVSDSDSDLTTFNISEDSSASQEKVQTFVDAYN
                     TLIDTVDSLTTHGDDSSSAGVFAGDAGLSSLANQLDDIAHASYNGVSIVDYGITLDSH
                     GHLQIDSDQFNDAMKSDPDGLTSIFVGDNSMVAQMDDLINTYTDSSNGIITLRQQNID
                     DQMSKIQDEGDQLTDTYNANYDRYLEEYTNTLVEVYTMKASMAAFA"
     gene            complement(4748..5662)
                     /gene="lafA"
                     /locus_tag="LSX49_003225"
     CDS             complement(4748..5662)
                     /gene="lafA"
                     /locus_tag="LSX49_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001570969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lateral flagellin LafA"
                     /protein_id="HBL7169603.1"
                     /translation="MLSINTNNASMAAVNAISKSSSSLSTSMERLATGNRINSSADDA
                     AGKQIANRLTAQSSGMGVALSNINDATAMLQTADSMFDEMSDVLGRMKDLSTQAANGT
                     YSDDDLQAMQDEYDELGQQMSDMLQNTTYGGTNLFGVSGTSNTGTDGLFQSAVTFQVG
                     AESSDTMTVNISSQLNTLVTDLSAISNSFSADQADTTGTAGVSGGTELTASGSANQMI
                     TSISTAMDDVSQIQSKLGASINRLNDTANNLTSMQDNTEVAIGNIMDTDYATEASNMT
                     KQQVLMQTGITMLKQSNSMSSMVSSLLQ"
     gene            6148..6990
                     /locus_tag="LSX49_003226"
     CDS             6148..6990
                     /locus_tag="LSX49_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBL7169604.1"
                     /translation="MSIIINNWRMDPSLNALIHCETGETRRLGEYHFILLETLAKNAD
                     VVLSRSYLCAEVWKNRIVGGNSLPTAIHALRVAIDDDGKQQNIIKTIPKKGYLCNKEY
                     VSFPESSPAEALIITDQIQKTTPEEISSTTPPVPVRKKHKGLMGLALAAAVILVGSTV
                     GYSHLKSTPDAPQLVKESINSPRIKIFHLSSGKENNSVPLLSQILAPGKDKLDNLLSA
                     HNMTMTTYYKYVRNRLESDIVLRNQCNGSWQLTFNVEGWQNSDINSAMYQNLEKLLNT
                     VQKC"
     gene            complement(7049..8026)
                     /locus_tag="LSX49_003227"
     CDS             complement(7049..8026)
                     /locus_tag="LSX49_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein"
                     /protein_id="HBL7169605.1"
                     /translation="MQVGLTSSSLATGGAHSAAVSSSTVASTQAVRQKLPATASEYPA
                     SPLITTRPQRYSVQLNDQLTTLQQADHYLGQLEQQLLDYRHSQRKGGQAQSTALMQML
                     DKRAALSGGAVDRELQPVLQGEARVTFHSPDLANLVHNPTPGTRMFSVSDGRQTQLSA
                     VMLSEDDSAGQYQTRLTNALRRVGVQVHQQADGISFSTTEKQWPDIERTLSVRTDGDK
                     SAFMPLKTFAEPSQAVRLAQSLQQGGAGISQTLESINQQRAQMAVQQEKARQLIDGMS
                     RFPQTENAVQASENLGGVLDSANHNYQILLQAVNGQARISSQTVRNLLG"
     gene            complement(8043..8972)
                     /gene="flgL"
                     /locus_tag="LSX49_003228"
     CDS             complement(8043..8972)
                     /gene="flgL"
                     /locus_tag="LSX49_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBL7169606.1"
                     /translation="MRVTTQQTYVSMTQSFNNLSGSLAHVVEQMATGKEILQPSDDPI
                     AATRITQLNRQQSAIEQYQSNIDSASAGLSQQESILDGVNNSLLVVRDDLLEAANGTN
                     TADSLASLGQDIESLTDSMVAALNYQDEDGHYVFGGTINDQPPIVAVDDDGDGVTDSY
                     SYQGNSDHRQTTVSNGVEVDTNVAASDFFGSNLDVLNTLNSLSQELQNPDVDPADPQV
                     QSDIQNAVDVVDTASDDLNASIASLGETQNTMSMLSDAQTDISTSNDELIGSLQDLDY
                     GPASITFTGLEVAMEATLKTYSKVSELNLFSVL"
     gene            complement(8987..10363)
                     /gene="flgK"
                     /locus_tag="LSX49_003229"
     CDS             complement(8987..10363)
                     /gene="flgK"
                     /locus_tag="LSX49_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000367241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBL7169607.1"
                     /translation="MDMINIGYSGASTAQVELNVTAQNTANAMTTGYTRQVAEISTIG
                     ASGGSPNSAGNGVQVDSIRRVSNQYQVNQVWYAASDYGYYSTQQGYLTQLEAVLSDDN
                     SSLSGGFDNFFAALNEATTSPDDSALREQVISEAGALSLRIDNTLDYIDSQSTEIISQ
                     QQAMVSQINTLTSGIASYNQQIAQAEANGDNASALYDARDQMVEELSGMMDVQVNIDD
                     QGNYNVTLKNGQPLVSGQQSSTIALETNADGTPTMSLTFAGTTSTMTTDTGGSLGALF
                     DYQNDVLTPLTDTINSMASQFADAVNNQLAQGYDLNGNPGEPLFIYDASNADGPLTVN
                     PDITADELAFSSSPDESGNSDNLQALINISTEPLEIANLGSVTVGQACSSIISNIGIY
                     SQQNQTEVDAASNVYSAAQNQQSSVSGVSMDEEAVNLITYQQIYEANLKVISAGAEIF
                     DSVLEMCS"
     gene            complement(10553..10852)
                     /locus_tag="LSX49_003230"
     CDS             complement(10553..10852)
                     /locus_tag="LSX49_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod-binding protein"
                     /protein_id="HBL7169608.1"
                     /translation="MKVNASGGIDGSDALMGPKVQANDIKQAAEQFEAIFLRNMLKEM
                     RKTNELFDSKDNPFNSDSVRMMQGFYDDELCNTLAQQHGIGIAAMLVKQLSPRHK"
     gene            complement(10852..11952)
                     /locus_tag="LSX49_003231"
     CDS             complement(10852..11952)
                     /locus_tag="LSX49_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HBL7169609.1"
                     /translation="MQNWIKAAAIAVSLTLPGVALAQSLESLVNVQGVRENQLVGYSL
                     VVGLDGTGDKNQVKFTNQTITNMLRQFGVQLPNKIDPKVKNVAAVAVSATLPPMYSRG
                     QTIDVTVSSIGDAKSIRGGTLLLTQLHGADGEVYALAQGSVVVGGMTATGASGSSVTV
                     NTPTAGLIPNGATVEREIPSDFQMGDTITLNLKRPSFKDANNIAAAINASFGGIATAQ
                     SSTNVSVRAPTSPGARVAFMSQLDDVQVQAEKIRARVVFNSRTGTVVMGDGVALHAAA
                     VSHGSLTVSINETSNVSQPNAFAGGRTAVTPQSNIAVNHARPGVVSLPESISLKTLVN
                     ALNSLGATPDDIMSILQALHEAGALDADLEVI"
     gene            complement(11967..12632)
                     /gene="flgH"
                     /locus_tag="LSX49_003232"
     CDS             complement(11967..12632)
                     /gene="flgH"
                     /locus_tag="LSX49_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002211429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HBL7169610.1"
                     /translation="MKNYLWLVALLPLLSGCESQAILVKKDDAYFAPPTTEAPPPADG
                     RAGGVFETGYNWSLTADRRAYRVGDILTVILEESTQSSKQAKTNFGKSNTVDIGAPTI
                     FGHTKDKLSGSIDANRDFDGSATSQQQNSLRGEITVSVHAVQPNGILEIRGEKWLTLN
                     QGDEYIRLSGLVRADDIQNDNSVSSQRIADARISYAGRGALSDANAAGWLTRLFNHPL
                     FPI"
     gene            complement(12715..13500)
                     /gene="flgG"
                     /locus_tag="LSX49_003233"
     CDS             complement(12715..13500)
                     /gene="flgG"
                     /locus_tag="LSX49_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003838810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HBL7169611.1"
                     /translation="MNAALWISKTGLSAQDAEMSAIANNIANVNTTGFKRDRVMFQDL
                     FYQTQEAPGAMLDQNNIMPTGLQFGSGVRIVGTQKTFTEGNVETTDNAMNVAIMGQGF
                     LQVQKANGDIAYTRDGNLQVNADGVLTNSQGLPLQPEIDVPAGATNVAFGEDGTVTAI
                     LPGDSDVTELGQLTLVNFANPAGLSAEGDNLYLETAASGQPTEGVPGEDGLGTLQDNA
                     LEGSNVDIVNEMVAMITVQRAYEMNAKMVSAADDMLQYISQTL"
     gene            complement(13579..14316)
                     /locus_tag="LSX49_003234"
     CDS             complement(13579..14316)
                     /locus_tag="LSX49_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgF"
                     /protein_id="HBL7169612.1"
                     /translation="MDRLIYTALSGASQTLYEQQISANNLANVNTNGFRADMAMATND
                     KVKGGGFDTRYMAQEGASGVNDSTGVAEKTERPLDVAIQGSGYIAVQDKNGNEVYTRN
                     GNIQQDDQGQLTIDGNLVLGDNGPIILPPNAIASFGSDGTLSVTPDDGDVTATMDIDR
                     LKLVDIPVANLAKNPEGMLVTADGVPAQRDENIKVSGGFLEGSNVSAVSEMMSSIAMN
                     RQFEAQIKMMKTAEDISDAGNRLLRGS"
     gene            complement(14316..15518)
                     /gene="flgE"
                     /locus_tag="LSX49_003235"
     CDS             complement(14316..15518)
                     /gene="flgE"
                     /locus_tag="LSX49_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body protein FlgE"
                     /protein_id="HBL7169613.1"
                     /translation="MSYEIAATGLNAVNEQLDGISNNIANAGTVGYKSMTTQFSAMYA
                     GSQAMGVSVAGTAQSISRGGSLVSTGNALDLAINDDGFFVTCDSAGNISYTRAGSFET
                     DKNGYIVNASGAYLQGYPVDDTGTLQTGTVTDIQIKTGNIPAQASSSLTFTANFDASD
                     AAIDRTTVPFDATNSSSYTDSYTTTVYDSLGNEHSVCQYFTKTSDNTWEVQYTFDGQQ
                     QTGVPATTLTFDPNTGKLTSPTTPQTIEFQTDAAAPIDLTVDYSTCTQYGSEFSVTTN
                     AADGYASATQNGVQVDDDGKVYATYSNGERMLQGQVVLATFPNENGLEAVSGTAWVQT
                     GESGTPLIGVPGSGTCGTLSSGVLESSNVDITSELVNLMTAQRNYQANTKVIATSTQL
                     DDALFQAM"
     gene            complement(15790..16503)
                     /locus_tag="LSX49_003236"
     CDS             complement(15790..16503)
                     /locus_tag="LSX49_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001508388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook capping protein"
                     /protein_id="HBL7169614.1"
                     /translation="MNTLALNAQSPQPTATAESNNVAASDTQSSSDSSPVDTFLTLFV
                     AEIQNQDPTDPTDATEYIDQLSSMAQVAMMEEMSVQANTNAVLMSNIQVMALGNLVGD
                     DIMVQTTALQVSDQTINGRATLDDACTTADLHFTDAAGDDYTVSLIPEGSSSVGPGQV
                     DFSINPADYGIPPGDYDVSVVTNTGEEEVPIEVSGEVEDVRIPLDGSSPVLNVAGVGE
                     VPFTMISQFGVPDADSDVA"
     gene            complement(16503..16934)
                     /gene="flgC"
                     /locus_tag="LSX49_003237"
     CDS             complement(16503..16934)
                     /gene="flgC"
                     /locus_tag="LSX49_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBL7169615.1"
                     /translation="MSFTDIYQISGSAMTAQTLRLNTVASNLANANAPASSEAQAYKA
                     RSPVFAAVYHHSLLAGTHRHAIDGASVQVQDVLQTGGAVKRYEPHSPLADANGDVWYP
                     DVNVVEQMADMMSASRDFETNVDVLNNVKSMQQSLLKLGEA"
     gene            complement(16937..17272)
                     /gene="flgB"
                     /locus_tag="LSX49_003238"
     CDS             complement(16937..17272)
                     /gene="flgB"
                     /locus_tag="LSX49_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005314272.1"
                     /note="with FlgF and C makes up the proximal portion of
                     the flagellar basal body rod; Yersinia has 2 copies of
                     flgB and other flagellar genes; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBL7169616.1"
                     /translation="MGISFQQALGVHPQAVKLRLERTELLTANLANVDTPNFKAKDID
                     FAREMQRANNAAVDVQYRVPMQPSEDGNTVELNSEQARFSQNSMDYQSSLTFLNLQIS
                     GIREAIEGK"
     gene            17354..18091
                     /gene="flgA"
                     /locus_tag="LSX49_003239"
     CDS             17354..18091
                     /gene="flgA"
                     /locus_tag="LSX49_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HBL7169617.1"
                     /translation="MSFQFCRRKFYFLLALALPGYAAVHPVQHSAREQVNAQVLNAAS
                     QKIESLAQQRRWHDYRYTFKVYIPSQIATAAPCTKTPGVTLTSPGDIALNRMNFTVSC
                     PQSWQMNVAVRPDVLVPVVMAKSLVARDTPLTANDVELKPYNVSAQRREVLMEPNDAI
                     GFSSKHALQPGRPITKEELISPVLVERDQPVMIVYQSAGITASMPGVALKNGRKGETV
                     KVRNASSQRVISAMVAESGVVTTVSAE"
     gene            18173..18451
                     /gene="flgM"
                     /locus_tag="LSX49_003240"
     CDS             18173..18451
                     /gene="flgM"
                     /locus_tag="LSX49_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBL7169618.1"
                     /translation="MKITPTMPGNHPTATMAGSSQPRKSTATTATTLSADDITQAGLQ
                     SAQQTLNDQQESDIDSDKVAQMQAMLASGSLQVDTEQLASDMLSFFQN"
     gene            18464..18892
                     /locus_tag="LSX49_003241"
     CDS             18464..18892
                     /locus_tag="LSX49_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBL7169619.1"
                     /translation="MSIRLQQVKALLQGIRDDDALYDSLRELLQRQRICMIRRAREDL
                     LAVNDEITQHYEQLHAHSHQRHSLLKMLGVSVNRDGLAQVFAWLPAVQKAAAQQLWQR
                     LEQKAERCKAYNDKNGELLIRQYEFIQAFLGSEADFLYQG"
     gene            19020..19952
                     /locus_tag="LSX49_003242"
     CDS             19020..19952
                     /locus_tag="LSX49_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-N-methylase"
                     /protein_id="HBL7169620.1"
                     /translation="MSFIECYEPEYVRNFMARHPDSPLYVRKVWKNEIRQSLMLTEPE
                     SCEAVLNDACAFDLQLTYRPVEENAAELSARDAIVNQAILSTLTLPDLTPELYLYAVG
                     IVLSRASKMPGRDGDILARLTTLPQALADHAQKGTLQAQFAQLPPVPQPARQLMTLLG
                     SCAFDWSILPESPRKTSLPLQMPLLTLHDANSKALLQQQLKVQWQTTWQQHFATAPWM
                     MRNWLIYRVYHEVIGQADGADYCPLVCDFYLIRTLISLWTLDGSPLRQEDIFALFAMF
                     ERWRESENAVLIRQQIQAERSADPLLYAFSLLSC"
     gene            19999..22437
                     /locus_tag="LSX49_003243"
     CDS             19999..22437
                     /locus_tag="LSX49_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001773846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL7169621.1"
                     /translation="MQTLIKTLVTHRVKPFVSVVTPTWNRGAFLPYLLYMYRYQDYPA
                     DRRELIILDDSPQSHQHIIDRLTNGTPESFNIRYIHHPEKLPLGKKRNMLNELARGEY
                     ILCMDDDDYYSPDKISYSIAMMQKHRALISGSDQIPIWYSHINRIFKSRSFGPHNILN
                     GTFCYHRNYLKKHRYDDDCNLGEEKSFTDNFSVNPLQLPGERTILCISHSHNTFDKDF
                     ILGASTPVNAVLTDIVSDPLLRNAYLGLHNATHYQAIHHQAIDQVVLINLDKRPDRLQ
                     QIREELTLLHIPPEKITRLAASENENGQRGRQQSHLQALRLAQQHGWQNYLLLEDDAV
                     ILKQEKHIQVLNALLASLAKIPWQVMILGGEISQGTMLKSLPGLVHARDCRKVCAYLV
                     NSRYYPQLAQQMNNDEHSLEDGWQPLLHTDKWLACYPSLCYQRQGFSDIEKKATDNIN
                     HYFNKLPVATKPSTLPIADTIGFFMETSFHYALYRPIITALQAQGQSCTLVINDRVFK
                     PFLDEMLATLKSIDDPQLKGMRLSEMQAHGQRVKCLVSPYHTPALNGLSTLNIRAMYG
                     LAKETWNHADWNRFYQRILCYSHYSQRALAHFGSAKVVGNPRFDAWHNGTFDRALPEN
                     IQPDSHKPTVLYAPTFGALSSLPHWAEKLGRLSGDVNLMCKLHHGTCSRPEEAASLAL
                     ARRHLKQRTDSARHTLALLAKADYVLTDNSGFIFDAIHVDKRVILLDFPGMTTLLDGE
                     KSYSTPESADQQIREILPVAHDVAELRYLLSEAFDWCAVQGQLAEIRHHYCDAFMDGK
                     AGERAAMVIMEALG"
     gene            22919..>23291
                     /locus_tag="LSX49_003244"
     CDS             22919..>23291
                     /locus_tag="LSX49_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169622.1"
                     /translation="MLQKIGYMEEDNIIEKKPWRGIPPEYTDRWREIYNNAAPEEGMH
                     LSDACPVCGDTELYRYYSLLKTQPRLLGGIMYKGPGSYWEWCGSCRSYEHMSGYVPIS
                     WVVELSGIDHSKLTAIPDMIDI"
BASE COUNT         5041 a         6463 c         6184 g         5603 t
ORIGIN      
        1 tttttgcatg atttcttcac tttaattcgg atagacaaaa tcacgaattt tctgcgcgat
       61 ctgtttattc agttgacaaa ttcgggcctc ggttagccct aataccagcg caatctcttt
      121 gagattcatc tcatgctggt aatacatgga gaggatcagt tgctcttttt cgcttaattg
      181 tgaaagcgcg tgttgcaaca tttgctgagt gacaaactga tcttccagtt cccggccagc
      241 aagcggaatg cctggccctt cgccgttcag cagttcgtcc aggctggcga gcgtttccgc
      301 cccttccagt tgctgatatt cgagataatc ttcatgcgag atcccttcct cagccagctc
      361 ctgccactcc ggttcgtgcc ccagtttttt acgcgtttcg cgaatcaggt ctttcatctg
      421 atgatatttc tgtcgcagct ggcgcggtcg ccagtcgaga gcgcgcagct catccaggat
      481 cgcaccgcga atacggtgca cggcatagcc cgcaaaacct tcgtccggca gcccatagcg
      541 acgaatggcg ttcaacagcc ccattaacgc cgtttgttcc atatcctgac ggtcaataat
      601 gcaattacac tgcggggcaa gttgccgcac cactttacgc accaacggta aataggcctg
      661 caagtagtgg ctctcctgct gcggagttaa taccagcgtg gctgcaaatt cttctgactc
      721 gaatacatcc tgtagcatgt ttatatccgc ctggtgatta ctggaagacc acttttttca
      781 ccagcaaatc cttatacggt gcggtcattt tgcgacgctg aagatctttc tttaacgcgt
      841 cagaaatcag tttgcggatg gcagatattt tcatgccgcg caaatcttca aatttcattt
      901 ccgtcaggca ttcaaccgca atactttgat acagcggttc ctgatgcttt attttttccg
      961 cctctttgtc actggcgacc accatcacta attccgccga caaataatga tccgcgccgt
     1021 tgttgtcatg caaagtgaca atggtttccg gcagcgtcac aaatacgctc ttgctctcat
     1081 ccagagcttc caccgattcc gtttgcgcgg cggtagtcgg ttttcctttt ccggcataat
     1141 gatgccagac actccatcct gctccagcgc cgaccaccaa cgccagaacg gcgctgacca
     1201 cgcctgccac cacgattttc ttcatattgc ctttacactt tgatcaaaac ggattcgttc
     1261 tgttgaaatt gaggcgcatc atcaagctgt aaggcggcac tcacctcttc ctgctgatgg
     1321 cccgactgtt gttgctgctg cgactgccct tcggaggaaa cctgtacgtt cacctccata
     1381 aaattttgcg ccgtcagatg ctggcggaga tcgtcgctaa actgctgcaa tgcgcggcag
     1441 acttcgcttt gattcgcacc gatatggacc gtcagtttgc cgttatccaa ctgtacggcg
     1501 atctcaagct tgccaagcga cggtggatcg agacgaatgg tggagatctg ctgttgtttg
     1561 ttgagctgaa agtggatctg atctttcaac agcgtcgtca gtttttcgcc cagttcgtcc
     1621 atcgaaagcg tggctggttt ggcgacaatc tcctgatgat cgctgaccaa ctctggcgtc
     1681 ttaacctgca acaccgcacg cgcaataacc ggttcgctgt ccggcacttt ttccgtttta
     1741 cgctcgacct gcgggcgcgc ggtcacacgg gttagttcag gtttcgggcg agctggcggt
     1801 gttgagacgc gcggctgcgt cggcgcaatg gcatgtaaat cttcactggc gtaagtcgcc
     1861 agtctggcct gctgttcggg tttcgcctgc ggcaactgac cgatcagttc ctgcaactgc
     1921 ggcggcaacg acgtgagttc ctgctgctgc gtcgggcgtt gcggcgcgtt ttgcaccacc
     1981 gctttcgtca attgctggat aaccggcgat gttgcgacgt ttcgcggctg cggcgtgtcc
     2041 tgatgcggcg cggcaggttg cggaagtaac agcgccatta gcgcctgcat cgccaccgga
     2101 tcgttctcct gcgggcgcgt cgcctgttgc tgactggttt tagcgctatg aacgcgctcc
     2161 gccaccgccg cgaccaccat tttcggcagg gtaaacacgg gcgcgttttc accgctcacc
     2221 ggcggtaaaa tatccgcctt caacgaagcg gtttccgcaa gcgttccgag cgtggcaagc
     2281 aatgccggat tcatgacttc tccgaaagta aattaacaat tgagtaggcc agtacgcctt
     2341 cctgatgccg ctgatgctgt tccatacgcg ctttcaacac ttctgcgcgc tgctcgcgcc
     2401 gtttaatcag ggcattaaac gcgccgtaca gttgtgcctt caccgcatcc aactgcgccg
     2461 cgtcggtttc cgccgccgcg taatcgtgaa actggcgcat caactgctga tacagtgccg
     2521 gaaggcgtcg ccagcgttgc ttgtcgaggg cgtcattcat cgcttcgacc agtgcaaaaa
     2581 gttgcctgcg ttgtttttcc atcgtcttaa cccagcttgc ccgaaagccc ttcccagcct
     2641 tcgcgcaggt tgcttaagat cagcatcact tcatcgattt tctctgccga cagttcgccg
     2701 ctggcttcat acaagcgata cacacagtgg tcatagaggc gcgaaaggtt gaccaccagc
     2761 tcgccgccgg tttcaaattc cagcgaactg gtgagcgcat tgagaatgtc gatgcattta
     2821 ttgatgctct gggctttctt ctcgaaacgc cgcccttcaa tgtggcttct ggcgcgttcc
     2881 agctcgtcca tcaggccaga aaacagcacc agcaccagtt caagaggcga tgccgccgcg
     2941 gtacgcgccg cgagatcgat ctctttgtat tgcgaataac cgtcctgtac ttggtacatc
     3001 tttaaggata ttccttctga attacgcaaa tgccgccata ctggctttca tggtgtacac
     3061 ctcaaccaac gtattggtgt actcctcgag ataacggtcg tagttagcgt tataggtatc
     3121 ggtaagctga tcgccttcgt cctgaatttt gctcatctga tcatcaatgt tctgctggcg
     3181 cagggtgatg atgccgttgc tggagtccgt gtaggtgtta atcaggtcgt ccatctgcgc
     3241 caccatgctg ttgtcgccaa cgaaaataga ggtcaggccg tcgggatcgc tcttcatcgc
     3301 gtcgttgaac tggtcggagt caatctgtaa gtggccgtga gaatcgagcg tgatgccata
     3361 gtcgacaatc gacacgccgt tgtagctggc atgggcgatg tcatcgagct ggtttgccag
     3421 tgagctgagt ccagcatccc ccgcaaagac cccggcgcta ctactgtcat caccgtgggt
     3481 ggttagcgaa tcaaccgtat caatcaaggt gttataggca tcgacaaagg tctgtacttt
     3541 ctcctggctg gcgctggaat cttcactgat gttaaaggtg gtgagatcgc tgtcagaatc
     3601 gctgacttcg gtaaaagtca tggtgacacc ggggatcaca tcatcaaacg tgttgctgct
     3661 gttggtgata gccggtccgc tggcgctacc gagatgaata atcgcgtcct gagcggagga
     3721 aacatccgtg gcaacgggcg cactggtgct atcgttgctg gcatcatgcc ccgttacgct
     3781 caccgaaaac gcgctctgcg ccccggtgct atcggaggtg agcataatcg tggtggtgcc
     3841 gtcggttttt accagtgccg ccgacacgcc cggattgtca tcggagtcgt taatcgcatt
     3901 caccagctcg ctggcgtcga taaaaccgtc accgtcaccg ttctgatctg ccgccgacag
     3961 atcgatatcc atagtgctgt cgcccatcgt cagttcaaaa gtaccggtag cggaaaaggc
     4021 gtcgtcgccc atactgaacg tggtttgctg cccctgcgcc agttgctcaa cgaaaaacga
     4081 gtagcttccc gcctgcgcct gggaattggc ggaaacggtc gccgagtcat tattgctggt
     4141 ggcggcaaaa gtcaccgggc cgtcggtatc gctgttcagc gcgtcaacgg cgctctggaa
     4201 atcgctcaac gccgagctga gcgagtccag gccgctgctt tcagcatcca gctcactctg
     4261 cttctcctgc aaattcgtcg cctgagtagc gacatccgca tacgcgattt cttgcgcaat
     4321 ggttcttggg ttgatcattg atgactccgg ataacaatgt caggttattg gcaaaaggcg
     4381 tgccaatatt ttttatgtga ataatcaata gattgaaaaa caggcggaaa tgacgtttcc
     4441 ggtctggcgg aaaaaagcct gccgcagaaa gcacaacacc gcccacaggc ggtgttgttc
     4501 gtggccggat aaggcgttta cgccgcatcc ggctatcggt gcacagtgcc tgatgcaacg
     4561 ctgacgcgtc ttatcaggcc tacgagtccg cgcctgtttt tatgcgtgtg cccatttgta
     4621 ggccggataa ggcgttcacg ccgcatccgg caatcggtgc acaacgcctg atgcgacgct
     4681 gacgcgtctt atcaggccta cgagtccgca catattttta tgcttgtgcc cgtttgtcgg
     4741 cccgaactta ctgcagcagg ctggaaacca tgctggacat gctgttggac tgtttcagca
     4801 tggtgatacc ggtctgcatc agcacctgtt gtttggtcat attggacgct tccgtcgcgt
     4861 aatcggtatc catgatgttg ccgatagcca cttcggtgtt gtcctgcatg ctggtcaggt
     4921 tgttggcggt gtcattcaga cggttgatag atgcacccaa cttggactga atctgagaaa
     4981 cgtcatccat cgcggtagaa atgctggtga tcatctggtt agccgagcca gacgcagtca
     5041 gttcagtacc gccagaaacg cctgcggtgc cagtggtgtc agcctgatcc gcactaaagg
     5101 agttgctgat agcagaaagg tcagtcacca gcgtgttcag ttggcttgaa atgttcacgg
     5161 tcatggtgtc ggaagattcc gcgcccacct ggaaagttac cgcgctctgg aacagaccgt
     5221 cagtaccggt gttgctggtg ccggaaacac cgaacaggtt ggtgccgccg taagtagtgt
     5281 tttgcagcat gtcagacatc tgctggccca gttcgtcgta ttcgtcctgc atcgcctgca
     5341 ggtcgtcgtc gctgtaggtg ccgttcgctg cctgcgttga caggtctttc atacgcccca
     5401 gcacgtcaga catttcgtcg aacatgctgt cagcggtttg cagcatcgcg gtagcatcat
     5461 tgatgttgct cagcgccaca cccataccgc tggactgtgc cgtcagacgg ttagcaattt
     5521 gtttgcctgc ggcgtcatcg gcagaagagt taatccggtt acctgtcgcc aggcgttcca
     5581 tagaagtaga cagagaagag ctgcttttgc tgattgcatt aacggcggcc attgaggcgt
     5641 tattggtgtt aatagataac atgatactgc tccttgggat taatcgtgtt cgtttcgata
     5701 ccctgtaaaa acgacacctc gggagcaaac ttaaaatcgc cgttaaaatt ttttcgccac
     5761 gtattatccg atgccacttt tagctaaaaa aagcagagtt taaattcaga taaaaagatt
     5821 attagcaata tctgccacat ggccaggtat caaaatatgt ctttatcaaa tgcttgatat
     5881 agttaagatt gtcatcaatt aacgcgtttt cttctcaatg tactgatgcc aaaatttaca
     5941 ttgcgttgca aatagtacac gtttggctat tgtacctgtc ctgtcatttc gttacatttc
     6001 cacgccatat agtgattaag aataatccta ttaccataaa atattaatta tcacgcagaa
     6061 aaatcatctt ctcagggacg tataagactg tgctttatgc aaagcactat caggaaacat
     6121 ttatcccttg ctaaggtaaa ctcaactatg agtattatta tcaacaactg gcggatggac
     6181 ccgtcgctta atgccttaat acattgcgaa acgggtgaaa cacgtcgtct cggcgaatac
     6241 cattttattt tgctggaaac attagcaaaa aatgccgatg tggttttatc gcgatcttat
     6301 ttatgtgccg aagtatggaa gaaccgcata gtcggcggta acagcctgcc gacggcgatc
     6361 catgcgttgc gcgttgctat cgatgatgat ggcaaacaac agaacattat taaaacaatt
     6421 ccgaagaaag ggtacctgtg caataaagag tatgtgtctt ttccggagtc atcgcctgcg
     6481 gaagcgctga ttattaccga ccagatacag aaaacaacgc cagaagagat atcttcgaca
     6541 acaccgcctg tacctgttag aaaaaaacat aaaggactga tggggctggc gttggccgcg
     6601 gctgttatat tggttggctc aaccgtgggg tattcacact tgaaaagtac acctgacgcc
     6661 ccgcaactgg taaaagagtc aattaacagt ccaagaataa aaatatttca tcttagttct
     6721 ggaaaggaaa ataattccgt accgttactg tcacaaatcc tcgcaccagg aaaagacaaa
     6781 ctcgataatt tattgtcagc gcataatatg acaatgacaa cctattataa atatgttcgt
     6841 aaccgactgg aaagcgatat tgttctgcgt aaccagtgca acggcagctg gcaattaacc
     6901 tttaatgtgg aaggttggca gaacagcgat attaatagcg cgatgtatca gaatttagag
     6961 aagttgttaa atactgtgca gaaatgctga caagtgccaa tatatgccgg atgcgacgct
     7021 aaacgcgtct tatccggcca accgataatt atcccaataa attcctcacc gtctggctgg
     7081 aaattcgcgc ctgaccgttc accgcctgca ataaaatctg atagttatga ttggcgctat
     7141 ccagcacgcc gccgaggttc tccgatgcct gcaccgcgtt ttccgtttgc gggaagcgtg
     7201 acatgccgtc gatcaactgg cgggcttttt cctgctgcac cgccatctgc gcgcgctgct
     7261 gattaatgct ttctaacgtc tgggaaatcc ccgccccacc ctgttgcaaa ctttgcgcta
     7321 aacgcacggc ctgcgacggt tcggcaaagg tttttagtgg cataaacgcc gacttatcac
     7381 catcggtgcg cacgcttaag gtgcgctcga tgtcaggcca ctgtttttcg gtggtggaga
     7441 aactgatgcc gtccgcttgc tgatgtacct gcacgcccac gcggcgcagg gcgttggtca
     7501 ggcgcgtctg gtactgcccg gcgctgtcat cctcagacag catcaccgcc gaaagctggg
     7561 tctgccgccc gtcagagaca ctgaacatgc gcgttcccgg cgtgggattg tgtaccagat
     7621 tcgccagatc cggcgagtgg aaggtcaccc gcgcttcgcc ctgcaacact ggttgtaact
     7681 cgcggtccac cgcgccgccg gaaagcgcgg cgcgtttgtc cagcatctgc atcagcgccg
     7741 tactctgcgc ctgcccgccc ttacgctggc tgtgacgata gtcgagcaac tgctgttcca
     7801 gttgcccgag atagtgatcc gcctgctgca acgtggtgag ctggtcgtta agctgtacgc
     7861 tgtaacgctg cgggcgagtg gtaatcagcg gcgaggccgg atattcactc gccgtcgccg
     7921 ggagtttttg ccgcaccgcc tgagtggacg caacggttga cgacgatacc gcagcgctat
     7981 gtgcgccgcc ggtggcgagt gatgaagatg taagtccgac ctgcatactg ttcctgaaag
     8041 agttagagaa cgctgaacaa attcaactca ctcactttcg agtaagtctt gagggtagct
     8101 tccattgcca cttccagtcc ggtaaaggtg atcgacgccg gaccgtaatc gagatcctgc
     8161 aatgaaccaa tcaattcatc attagatgtc gagatatcgg tctgtgcatc gctcaacatc
     8221 gacatggtgt tttgtgtctc gccgagcgac gcaatcgagg cgttgaggtc gtccgaggcg
     8281 gtgtccacca catcgacggc gttctgaata tcgctctgca cctgcggatc tgccgggtcg
     8341 acgtccgggt tttgcagttc ctgcgacaag gaattaagcg tgttaagcac gtctaaattg
     8401 ctaccgaaaa aatcgctcgc cgccacgttg gtgtccactt ccacaccgtt cgacacggta
     8461 gtctggcgat ggtcgctgtt gccctgatag ctatagctgt cggtgacgcc atcgccatca
     8521 tcgtctaccg cgacaatcgg cggctgatcg ttgatggtgc cgccaaacac gtagtgcccg
     8581 tcttcgtcct gataattgag cgccgccacc attgaatcgg tgagcgactc aatatcctgg
     8641 ccgaggcttg ccagcgaatc ggcggtattg gtgccgttcg ccgcttcaag caggtcgtcg
     8701 cgtaccacca gcaggctgtt gttgacgcca tcgagaatcg attcctgctg gcttaagccc
     8761 gccgacgcgg agtcgatatt gctctgatac tgttcaatcg ccgactgctg gcggtttaac
     8821 tgggtgatgc gcgtggcggc gattgggtca tccgacggct gcaaaatttc cttgccggtt
     8881 gccatctgct cgaccacatg cgccagagag ccggagagat tattaaaact ttgcgtcatc
     8941 gagacgtagg tttgttgggt ggttactcgc attttcgcgc tcccgcttag ctgcacattt
     9001 ccagcaccga atcgaaaatc tcggccccgg cggaaatgac tttcagatta gcttcataaa
     9061 tttgttgata ggtgatcagg ttcaccgctt cttcgtccat gctgacgccg ctgacgctac
     9121 tctgctggtt ttgcgctgcg gaatagacat tggacgcggc atcgacttcc gtctgatttt
     9181 gctgactgta aatgccgata ttgctgatga ttgacgagca cgcctgcccg accgtcacac
     9241 tgccgaggtt ggctatctcc agcggttcgg tggagatatt gatcagcgcc tgcaggttgt
     9301 cgctgttgcc gctttcgtcc ggtgaactgg aaaacgccag ctcatcggca gtgatatccg
     9361 ggttaacggt cagtgggcca tcggcattgc tggcgtcata aataaacagt ggctcgccgg
     9421 ggttaccgtt gagatcgtag ccctgcgcca gctggttgtt gaccgcatcg gcgaactgcg
     9481 acgccatgct gttgatggtg tcggtcagcg gcgtcagcac gtcgttttga tagtcgaaca
     9541 gagcgcctaa cgaaccgcca gtgtcggtgg tcatggtcga ggtggtgcca gcgaaagtca
     9601 gcgacatggt cggtgtgccg tcggcgttgg tttccagcgc gatggtcgag ctttgctgcc
     9661 cgctcaccag cggctgaccg tttttcaggg tgacgttgta gttgccctgg tcgtcaatat
     9721 tgacctgcac gtccatcatt ccgctcagtt cttccaccat ctgatcgcgg gcgtcgtaca
     9781 gcgcggaggc gttatcgccg ttggcttcgg cctgagcgat ttgctggtta tagctggcga
     9841 tgccgctggt cagcgtattg atttgcgata ccatcgcctg ctgctgactg atgatttccg
     9901 tgctttgcga gtcgatgtaa tccagcgtgt tgtcgatgcg caacgacagc gccccggctt
     9961 cgctgatcac ctgctcgcgc agggcggaat catcggggct ggtggtcgct tcgttaaggg
    10021 cagcgaaaaa gttatcgaag ccgccgctca gactgctgtt atcgtcgctc agtaccgctt
    10081 ccagttgtgt gagataccct tgttgggtgc tgtaatagcc gtaatcgctg gcggcatacc
    10141 atacctgatt aacctgatac tggttggaga cgcggcgaat actgtcgacc tgcacgccgt
    10201 taccagcgct gttcggcgaa ccaccgctgg caccgatggt gctgatctcc gccacctggc
    10261 gggtgtagcc cgtggtcatg gcgttagcgg tgttttgcgc cgtgacgttc agctccacct
    10321 gcgccgttga tgcgccgctg tagccgatgt taatcatgtc catgttgggt ccttaccggt
    10381 aaatcgtgcc ggttaaaagc ggcgtgaagt tggggattct taagttccgt aaaccgggtg
    10441 ccaaatgccg gatgcggcgt aaacgcctta tccggcctac atactacata cgggcgactc
    10501 gtaggcctga taagacgcga cagcgtcgca tcaggcaccg aacgccgaag cctcatttat
    10561 gcctgggcga caactgcttc acaagcatcg ccgcaatccc aatcccgtgc tgctgcgcca
    10621 gggtgttaca caactcatcg tcataaaacc cctgcatcat gcgcaccgaa tcgctgttaa
    10681 acgggttatc tttcgaatca aacaactcgt tggttttacg catctctttc agcatgttgc
    10741 gtaaaaaaat cgcctcaaac tgctccgcgg cctgcttaat atcattggcc tgaaccttcg
    10801 gccccattaa cgcatcgctg ccgtcaatcc cgccgctggc gttcactttc atcagatcac
    10861 ctccaggtcg gcatccagcg cgcccgcctc atgcagcgcc tgtaaaatcg acataatgtc
    10921 gtccggcgtt gcgcctaaac tgttcagcgc attgaccagc gttttcaggc tgatcgactc
    10981 cggcaaactc accacgcccg ggcgcgcatg attcaccgcg atattgctct gcggcgttac
    11041 cgccgtgcgc ccgcccgcaa aagcatttgg ctggctgacg ttgctggttt cgttaatcga
    11101 gacggtcaaa ctgccgtgcg acaccgccgc cgcatgcagc gcaacgccat cgcccatcac
    11161 caccgtgccg gtacgcgagt taaacaccac gcgggcgcgg attttctctg cctgcacctg
    11221 tacatcatcc agttgcgaca taaatgccac ccgcgcgccg gggctggtgg gcgcacgcac
    11281 gctgacgttg gtagagctct gcgcagtagc aatgccgcca aacgaggcgt taatcgccgc
    11341 cgcaatattg ttggcatctt taaacgacgg acgtttcagg ttgagggtga tagtgtcgcc
    11401 catctgaaaa tcgctgggga tctcgcgctc taccgttgcg ccgttaggaa ttaacccggc
    11461 ggttggcgta ttaaccgtta cgctcgaacc gctggccccg gtggcagtca tcccgcccac
    11521 caccacgctg ccctgcgcca gcgcataaac ttcgccatcc gcgccgtgca actgggtcag
    11581 caacaaagtg ccgccacgaa tacttttggc atcgccaatc gacgaaacag tgacatcgat
    11641 ggtctgcccg cgcgagtaca tcggcggcag cgtggcgctc accgctaccg cggcgacgtt
    11701 tttcaccttc ggatcgattt tatttggcag ttgcacgcca aactggcgca gcatattggt
    11761 gatggtctgg ttggtgaatt tgacctggtt tttatcacca gtaccgtcga ggcctaccac
    11821 caggctgtag ccgaccagtt ggttttcacg cacgccctgt acgttgacca acgactccag
    11881 cgattgcgcc agcgccacgc cgggcagcgt cagacttaca gcgatcgctg cggcctttat
    11941 ccagttttgc attgcactct ccggcattaa atcgggaaca gaggatggtt aaacagccgc
    12001 gtcaaccagc ctgcggcgtt ggcgtcgctt aacgcgccgc gtccggcata ggagatgcgg
    12061 gcatcggcga tccgctgcga ggaaaccgag ttgtcgtttt ggatgtcgtc ggcgcgcacc
    12121 aggccgctta agcggatgta ctcatcgccc tggttgagag tcagccattt ttcgccgcga
    12181 atttccagga tgccgttagg ctgcaccgca tggacggaaa cggtgatctc cccgcgcagg
    12241 ctgttctgct gctgggaagt ggcgctgccg tcaaagtcgc ggttggcgtc gatagagccg
    12301 gaaagtttat ctttggtgtg tccaaaaatc gtgggcgcgc cgatatcgac ggtgttgctt
    12361 ttgccgaagt tggttttcgc ctgtttgctc gactgggtgg actcttcgag gatcaccgtc
    12421 aggatatcgc ccacgcggta agcccgccgg tcggcggtga gcgaccagtt gtagccggtt
    12481 tcaaacacgc ccccggcacg cccgtctgcc ggaggcggcg cttcggtggt tggtggcgca
    12541 aagtatgcgt cgtctttttt gaccagaatg gcctgcgatt cacacccgct aaggagtgga
    12601 agcagcgcca ccagccagag ataatttttc acgttctgcc tgtttaaata cagtgagtta
    12661 tgtgctcttg taggtcggat aagacgcgtc agcgtcgcat ccgacatttc ggccttacag
    12721 cgtctggctg atgtactgca acatatcgtc cgcagccgag accattttgg cgttcatctc
    12781 gtacgcccgt tgcaccgtaa tcatcgccac catctcgttg acgatatcca cgttcgatcc
    12841 ttccagcgcg ttgtcctgca aggtgccaag cccatcttcg cccggtacgc cttcggtcgg
    12901 ctgaccgctg gcggcggttt ccagatagag gttgtcaccc tcagcggaaa gcccggccgg
    12961 gttggcgaag ttcaccagcg tcagttgccc taactcagtc acgtcgctgt cgccgggtaa
    13021 gatcgccgtc accgtgccat cctcaccaaa agcaacatta gtcgcccccg ccggaacgtc
    13081 gatttccggc tgcaacggca agccctgcga gttggtcagt acgccgtcag cgttcacctg
    13141 caagttgccg tcgcgggtat aagcgatatc gccgttggcc ttttgcacct gcaaaaaccc
    13201 ctgccccata atggcgacat tcatcgcgtt gtcggtggtt tcgacgttgc cttcggtgaa
    13261 ggttttctga gtgccgacaa tgcgtacgcc gctaccgaat tgcagcccgg tcggcataat
    13321 gttgttctga tcgagcatcg cgcccggcgc ttcctgggtc tggtaaaaca gatcctgaaa
    13381 catcacccgg tcacgcttga agccggtggt gttaacgttg gcgatgttgt tggcaatcgc
    13441 gctcatttca gcatcctgcg ccgagaggcc ggttttgctg atccatagtg ctgcgttcat
    13501 ggtggtaaat tccgtgttat tttttggccg cggttgccgg atgcggcgtg aacgccttat
    13561 ccggcctacg atgtgcgatt acgagccgcg caataagcgg ttgcccgcgt cgctgatatc
    13621 ttcggcggtt ttcatcatct tgatctgcgc ttcgaactgg cggttcatgg cgatggacga
    13681 catcatctcg ctcaccgccg agacgttgct gccctcgaga aaaccgccgc tgactttgat
    13741 gttttcatcg cgctgggccg gaacgccgtc ggcagtcacc agcatccctt caggattttt
    13801 cgccaggttc gcgaccggga tatccaccag cttcaggcgg tcgatatcca tcgtcgcggt
    13861 cacgtcaccg tcatcgggcg tcacggagag cgtgccgtcg ctgccaaacg aagcaatggc
    13921 gttgggcggc agaatgatcg gcccgttatc tcccagcacc agattgccgt cgatagtcag
    13981 ttgcccctgg tcatcctgct gaatgttgcc gttgcgggta tacacttcgt tgccgttttt
    14041 atcctgcaca gcaatgtaac ccgaaccctg aatcgccacg tccagtgggc gttcggtttt
    14101 ctccgcaaca ccagtgctgt cgttcacgcc gctggcccct tcctgcgcca tatagcgcgt
    14161 gtcgaagccg ccgcctttca ccttatcgtt agtcgccatt gccatatcgg cgcgaaaacc
    14221 gttggtgttg acgtttgcca ggttgttggc gctgatctgc tgctcgtaca gggtctgaga
    14281 agccccgctc agggcggtat aaatcaagcg gtccattaca ttgcctggaa cagcgcgtca
    14341 tcgagctgcg tgctggtggc gataactttg gtgttggcct gatagttacg ctgggcggtc
    14401 atcaggttga ctaactcgct ggtgatatcg acgttagagc tttcgagcac gcccgacgac
    14461 agcgtgccgc aggtgccgga accgggaacg ccaatcagcg gggtgccgga ttcgccggtt
    14521 tgtacccacg cggtgccgct cactgcctcc aggccgtttt cattcgggaa cgtcgccagc
    14581 accacctgcc cctgcaacat gcgctcgccg ttgctgtagg tagcgtaaac tttgccatcg
    14641 tcatcaacct gcacaccgtt ctgagtggca gaggcgtagc cgtcggcggc gttggtggtg
    14701 accgaaaatt cagagccgta ttgcgtacag gtcgagtaat cgacggttaa atcgatgggt
    14761 gcggcggcgt cggtctgaaa ctcaatggtc tgcggcgtgg ttggcgaggt cagtttcccg
    14821 gtgttcgggt cgaaggttaa cgtcgtcgcc ggaacgccgg tctgctgctg accgtcgaag
    14881 gtgtactgca cttcccaggt gttgtcgctg gttttggtga agtactggca taccgaatgt
    14941 tcgttgccta atgagtcata caccgtggtg gtgtagctgt cggtgtacga gctgctgttg
    15001 gtcgcgtcga acggtacggt agtgcggtcg atagccgcat cgctggcatc gaagttggcg
    15061 gtaaaggtca ggctgctgct ggcctgcgcc ggaatattac cggttttgat ctggatatcg
    15121 gtgactgtac cggtttgcag ggtgcccgtg tcatcgaccg gatagccctg caaataagcg
    15181 cccgaggcgt tgacgatata gccgtttttg tcggtttcaa acgatccggc gcgggtataa
    15241 gaaatgttgc ccgcgctgtc gcaggtaaca aaaaagccgt cgtcgttaat cgccagatcc
    15301 agcgcgttac cggtggatac cagcgaaccg ccgcgcgaaa tactttgcgc ggtgcctgcc
    15361 acgctgacgc ccatcgcctg acttccggca tacatggctg aaaactgggt ggtcatcgac
    15421 ttatagccta ccgttccggc gttggcgatg ttgttactga tcccgtccag ctgttcgtta
    15481 acggcattca gccccgttgc agcaatttca taactcattg tgtcttcctg ttaattcaga
    15541 ttttggcagc gtgcccgttg ttttgccgga tgcggcgtga acgccttatc cggcctacga
    15601 acgggtgcaa acataaaaat atgcgcgaac tcgtaggcct gataagacgc gttaagcgtc
    15661 gcatcaggca tcttgcaccg aacgccggat gcggcgtgaa cgccttatcc ggcctacaaa
    15721 accattcgga ttcaatagtt tcatgtaggc ctgataagcg aagcgcatca ggcaatttgg
    15781 caccggacat cacgccacat cactgtcggc atcgggtacg ccaaactggc taatcatggt
    15841 gaacggcact tcgcctacac cggcaacgtt aagcaccggg gagctgccgt cgagcgggat
    15901 gcgcacatcc tccacttcgc cggaaacttc aatcggcacc tcttcttccc cggtgttggt
    15961 gaccaccgag acgtcgtaat cgcccggcgg gataccgtaa tccgccggat taatcgagaa
    16021 atccacctga cctggcccga cggacgaact gccttccggg atcagcgaca ccgtatagtc
    16081 atcgcctgcg gcatcggtaa agtggagatc ggcggtggta caggcgtcgt caagcgtggc
    16141 gcgaccatta atggtctggt cgctcacctg caaggcggtg gtctgcacca taatgtcgtc
    16201 acccaccagg ttgccgagcg ccatcacctg aatgttgctc atcagcaccg cgttggtgtt
    16261 ggcctgcacg ctcatctctt ccatcatcgc cacctgcgcc atcgaagaaa gctggtcgat
    16321 atattcggtg gcgtcagtcg ggtcggtcgg gtcctggttt tggatctcag cgacaaacag
    16381 cgtcaggaag gtatcgacgg gcgagctatc gctgctactt tgcgtgtcgc tggccgccac
    16441 gttgttgctt tccgccgtgg cggtcggctg cggtgattgc gcattcagcg ccagggtatt
    16501 catcaggctt ctcccagttt cagcaaactt tgctgcatac ttttcacgtt gttgagcaca
    16561 tcgacattgg tttcgaaatc gcgcgaagcc gacatcatgt ccgccatctg ttccaccacg
    16621 ttgacgtcgg gataccagac atccccgtta gcatcggcga gcggcgaatg tggttcatag
    16681 cgtttcacag ctccgccggt ttgcagcacg tcctgcacct gcacactggc accgtcaatg
    16741 gcatgacgat gtgtacccgc cagcaaactg tggtgataca ccgccgcaaa caccgggctg
    16801 cgcgctttat atgcctgcgc ctcgctgctg gcgggcgcat tggcattcgc caggttactg
    16861 gcaacggtat tcagacgcag cgtttgcgcc gtcatcgccg aaccggaaat ctgatagata
    16921 tcagtaaatg acatgcttat ttcccttcaa tggcctctct gatgccgctg atttgcagat
    16981 tcagaaaggt cagactgctt tgataatcca tactattttg tgaaaaccgc gcttgttcgc
    17041 tgttcagttc cacggtgttg ccatcttccg acggctgcat cggcacacgg tactggacat
    17101 ccaccgccgc gttatttgcc cgttgcatct ccctggcaaa atcaatatct ttagccttga
    17161 aatttggcgt atcgacgttc gccagattcg cagtcagtag ctcggtcctc tcaagacgta
    17221 acttcactgc ctgcggatgt actcccaatg cctgctgaaa actgatcccc atttcctgcg
    17281 tcactcctgc ttcaatccgc atacgctaag caatcgccgt gccatttttt aagtgactga
    17341 agagaaaggg tttatgagtt ttcaattttg caggcggaag ttttatttcc tcctggcgct
    17401 ggccttaccg ggctacgccg ccgtccatcc cgtgcagcac agcgcgcggg aacaagtcaa
    17461 cgcccaggta ctgaatgccg ccagccaaaa aattgaatcg ctggcgcaac agcggcgctg
    17521 gcatgactat cgctacacct ttaaggtcta cattccctcg cagattgcga ccgccgcgcc
    17581 ctgtactaaa acacccggcg ttacgctgac ttcgcctggg gacatcgccc tcaaccggat
    17641 gaacttcacc gtcagttgcc cacaaagctg gcagatgaac gtagcggtgc gtccggatgt
    17701 actggtgcca gtagtaatgg cgaagtcact ggttgcccgc gatacgccgc tcaccgcgaa
    17761 tgatgtggag ttgaagcctt acaacgtcag tgcccagcgc cgggaggtgt tgatggaacc
    17821 caatgacgcg attggtttca gcagtaaaca cgcgctgcaa ccgggcaggc caatcaccaa
    17881 agaagaactg atatctccgg tgctggtcga gcgcgatcaa ccggtgatga ttgtttacca
    17941 gagcgcgggg atcaccgcct caatgcccgg cgtagcactg aaaaatggtc gcaaagggga
    18001 aacggtgaag gtgcgtaacg ccagcagcca gcgggtcatc agcgcgatgg tggcggaaag
    18061 cggcgtggtg acaacggtaa gcgcggagta atttgcgcgg gcgattaaag ttttgccgcc
    18121 tgttaaccgc tttaccggag taacccaccc aaaataccga gacgaggtta cgatgaaaat
    18181 caccccgact atgccaggca atcacccgac agccacaatg gcaggctcca gtcagccgcg
    18241 caaaagcacg gcgaccaccg ccacgacgct gagcgccgat gacattaccc aggcgggatt
    18301 gcagtctgcc cagcaaacgc tgaacgacca gcaagagagc gatatcgaca gcgacaaagt
    18361 ggcacaaatg caggcgatgc tagcctccgg cagcctgcaa gtggacaccg agcagttagc
    18421 cagcgacatg ctgagttttt tccagaacta agaggccgat gaagtgagta tccggttaca
    18481 acaggtgaag gcgttgttgc agggaattcg tgacgacgac gcactgtacg attccctgcg
    18541 tgaacttctc cagcgtcagc ggatctgcat gattcgccgc gccagagagg atctgctggc
    18601 ggtaaacgac gagataacgc agcactatga gcagttgcat gcgcatagcc atcagcggca
    18661 tagcctgctg aaaatgctcg gtgttagcgt aaatcgtgac ggtctggcgc aggtttttgc
    18721 ctggcttccg gcggtacaaa aagcggcagc gcaacagttg tggcaacgcc ttgagcaaaa
    18781 agcagaacgc tgcaaagcct ataacgataa aaacggcgag ctgttaattc gccagtatga
    18841 atttattcag gcttttttag gcagcgaagc ggattttctc tatcagggat aacgacaatt
    18901 ccttccccca tcgcggaaac ggattttccg cctgatcccc aatcctttgt ttttgattaa
    18961 aaaaattccc ggcacgctta ttgcacatcc tgcaaggtaa taaagactgg aaactaccta
    19021 tgagttttat tgaatgttac gaaccggaat atgtgcgcaa ttttatggca cgccaccccg
    19081 attcgccttt atacgtccgc aaggtgtgga aaaacgagat tcgccagagc ctgatgctga
    19141 cagagccaga aagctgcgaa gcggtgctca acgatgcctg cgcctttgat ttacagctca
    19201 cctaccgccc ggtggaagaa aatgccgcag aactctccgc gcgcgatgcg atagtaaacc
    19261 aggccatttt gagcaccctt acgctccccg atttaacccc ggagctttac ctgtatgccg
    19321 tcggaattgt gctctcccgc gccagtaaaa tgccgggcag agatggagat attcttgccc
    19381 gcttgacgac gctgccacag gcgctggccg atcatgcaca aaaaggcacg ctacaggcac
    19441 agttcgccca gctcccgccc gtgccacagc cggcgcgcca gttgatgacg ctgctcggca
    19501 gttgtgcatt tgactggtcg attttgccgg aaagcccgcg caaaacttcc ctgccgttgc
    19561 aaatgccttt gctgacgcta catgacgcca acagcaaagc cctgttacaa cagcagctta
    19621 aggtgcagtg gcaaaccacc tggcaacagc attttgccac cgcgccgtgg atgatgcgta
    19681 actggctgat ttaccgcgtt taccatgagg tgattggaca ggcagacggc gcagattatt
    19741 gcccgctggt gtgcgatttt tatcttatcc gcacgttaat cagtttatgg acgctggatg
    19801 gttctccgct gcgacaggag gatattttcg ccctcttcgc catgtttgaa cgctggcgag
    19861 agagtgaaaa tgccgtgctg attcgccaac aaattcaggc tgaacgttcc gcagatcccc
    19921 tgctttatgc gttttcactg ctgtcttgct aacgctttct ggccggtttt cccggcctta
    19981 tcgacttcgt aaactatcat gcaaaccctc atcaaaacac tcgtcactca ccgcgtaaaa
    20041 ccgtttgtca gcgtcgtcac gccaacctgg aaccgcggcg cattcctgcc gtacctgctt
    20101 tatatgtacc gctatcagga ctacccggca gaccgccgcg aactcatcat cctcgacgac
    20161 tccccgcaaa gccatcaaca catcatcgac cgcctgacca atggcacgcc ggaatccttc
    20221 aacatccgct acatccatca cccggaaaaa ctgccgctgg gcaaaaaacg caatatgctc
    20281 aacgaactgg cgcgcggcga atacatcctc tgcatggacg atgacgacta ctactcgcca
    20341 gataaaatct cttactccat cgccatgatg caaaaacacc gggcgctcat ctccggttcc
    20401 gaccagatcc ccatctggta cagccacatc aaccgcattt tcaaaagccg cagctttggc
    20461 ccacataaca tcctcaatgg caccttttgc tatcaccgta actacctgaa aaagcaccgt
    20521 tacgacgacg attgtaattt aggcgaggag aaaagtttca ccgacaattt cagcgttaac
    20581 ccgctgcaac tgcccggcga gcgcacgatt ctgtgtatct cgcacagcca caacaccttt
    20641 gataaagact ttatcctcgg ggccagcacg cctgtaaacg cggtgcttac ggatatcgtc
    20701 agcgatccgc tgctacgcaa cgcttatctg ggtctgcata acgccactca ttatcaggcg
    20761 atccaccatc aggcgatcga tcaggtcgta ttgatcaatc tggataaacg cccggatcgc
    20821 ttacagcaga tccgtgaaga actgacattg ctgcatattc cgcctgagaa gatcacccgc
    20881 cttgccgcca gtgaaaatga aaacggtcaa cggggccgcc agcaatcaca cttgcaggcg
    20941 ctgcgtctgg cgcaacagca cggctggcaa aactacctgt tgctggaaga tgacgcggtt
    21001 attctcaaac aggagaaaca tattcaggtg ctgaacgcgc tgctggcgag tctggcgaaa
    21061 attccctggc aggtgatgat cctcggcggc gaaatttcgc agggaacgat gctaaaaagt
    21121 ttgcctgggc tggtgcacgc gcgggactgc cgcaaagtgt gcgcttatct ggtgaacagc
    21181 cgctactacc cgcagctggc gcagcagatg aacaacgatg agcattcgct ggaagacggc
    21241 tggcagccgc tgctgcacac cgacaaatgg ctggcctgtt acccgagcct ttgttatcag
    21301 cgacagggct ttagtgatat cgagaaaaaa gcgactgata acattaacca ctacttcaat
    21361 aagttacccg tagccaccaa gccatctaca ttacctatcg ccgataccat cggctttttt
    21421 atggaaacct cattccacta cgcgctctac cgcccaatca tcaccgccct gcaggcgcag
    21481 gggcagagct gtacgctggt gatcaatgac cgcgtattta aaccatttct ggatgaaatg
    21541 ctggcgacgc taaaaagcat cgacgatccg cagctcaaag gaatgcgctt atctgaaatg
    21601 caggcacacg gtcagcgagt gaaatgcctg gtcagcccct atcacacgcc cgcgctcaat
    21661 ggcctttcaa ccctgaacat tcgcgccatg tacggcttag ccaaagaaac gtggaaccac
    21721 gccgactgga accgttttta tcagcgcatt ttgtgttaca gccactacag ccagcgggcg
    21781 ctggcacatt tcggcagcgc aaaagtggtc ggcaatccgc gcttcgacgc ctggcataac
    21841 ggcacgtttg accgcgctct gccggaaaat atccaacccg attcccataa acctacggtg
    21901 ctctacgccc ccacgtttgg cgcattaagc tccctgcccc actgggcaga aaaattgggc
    21961 cgcttaagcg gtgatgtgaa cctgatgtgc aaactgcacc acggcacttg ctcgcgcccg
    22021 gaagaagctg catcgctggc actggcgcgc aggcatttaa aacagcgcac cgactctgcc
    22081 cgccacacgc tggcgctact ggcaaaggcc gattacgtgc tgaccgataa cagcggcttt
    22141 attttcgatg ctattcacgt tgataagcgg gtgatcctgc tcgactttcc gggcatgaca
    22201 acgttgctcg acggtgagaa aagttattcc acgcccgaaa gtgccgacca gcaaattcgc
    22261 gaaatattgc cggtggctca tgatgttgcg gaattacgtt atctgctatc agaggcgttt
    22321 gactggtgtg cggtacaggg gcaactggcg gaaattcgtc atcactattg cgatgcgttt
    22381 atggatggca aggcgggaga acgggcggcg atggtgatta tggaggcgct ggggtaaacc
    22441 gcgcaagtgc ctgatgcgct tcgcttatca ggcctacgcg cccctgcaat atagtgaatt
    22501 tgcgatgatt tgtcggccgg aaaaggcgtt tacgccgcat ccggcacgaa cagtgcactt
    22561 atctaccctt cgatttcaaa tacatcgctt tatggctggt taatcggtaa aagttgcaca
    22621 ttttgatagc gagaagagct gtctttatga attccgaaaa gcgcccttct accctctata
    22681 accattcttt tttacctgta ttggccgcaa catacctcac ccacgaagtg gttgtagcaa
    22741 ttcgtgggct aaaggtccgc attatatgaa acgggagggc ggtagcattt ctgatattac
    22801 atgcctcaat tttgctgaac tattggctat cctggacctc aaaaatctgg tcataagata
    22861 gattttttaa gggaatacgg agtaaaggtg tggaaaacta attaataggt ttgtcttaat
    22921 gcttcagaag attggataca tggaagaaga taatattata gagaaaaaac catggcgtgg
    22981 gatcccacct gaatacacgg atagatggag ggaaatttat aacaacgctg ctcccgaaga
    23041 agggatgcat ttatcagatg cttgtccagt atgtggtgat acggaattat atcgctatta
    23101 ttctctgtta aaaacgcaac cacgcttatt aggagggatt atgtataaag gacctggaag
    23161 ttattgggaa tggtgtgggt cttgtcgttc ctatgaacat atgtcaggct atgtaccaat
    23221 atcgtgggtt gtggagttat caggaataga tcattcaaaa ttaacggcca ttccagatat
    23281 gattgatatt g
//
LOCUS       DAFGPF010000074        23257 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFGPF010000074 DAFGPF010000000
VERSION     DAFGPF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23257
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.074"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            139..705
                     /locus_tag="LSX49_003245"
     CDS             139..705
                     /locus_tag="LSX49_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HBL7169623.1"
                     /translation="MSFTNTPERYGVISAALHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLPSYSPMTRLAAKAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLSDAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
     gene            709..1284
                     /locus_tag="LSX49_003246"
     CDS             709..1284
                     /locus_tag="LSX49_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HBL7169624.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGNLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(1326..2378)
                     /locus_tag="LSX49_003247"
     CDS             complement(1326..2378)
                     /locus_tag="LSX49_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706977.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBL7169625.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKVTRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLGIPDPTE"
     gene            2603..3523
                     /gene="lpxL"
                     /locus_tag="LSX49_003248"
     CDS             2603..3523
                     /gene="lpxL"
                     /locus_tag="LSX49_003248"
                     /EC_number="2.3.1.241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) lauroyltransferase"
                     /protein_id="HBL7169626.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLARMSGACLVPFVPRRKPDGKGYQLIILPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            3695..4921
                     /gene="mdtG"
                     /locus_tag="LSX49_003249"
     CDS             3695..4921
                     /gene="mdtG"
                     /locus_tag="LSX49_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HBL7169627.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQISN"
     gene            5004..5378
                     /locus_tag="LSX49_003250"
     CDS             5004..5378
                     /locus_tag="LSX49_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secY/secA suppressor protein"
                     /protein_id="HBL7169628.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAENANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQDENTLHEWDEGE
                     FQLEPPLDTEEGRTAADEWDER"
     gene            complement(5379..5606)
                     /locus_tag="LSX49_003251"
     CDS             complement(5379..5606)
                     /locus_tag="LSX49_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HBL7169629.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDIHHGPYE"
     gene            complement(5778..8321)
                     /gene="mdoH"
                     /locus_tag="LSX49_003252"
     CDS             complement(5778..8321)
                     /gene="mdoH"
                     /locus_tag="LSX49_003252"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HBL7169630.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDVWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            complement(8314..9849)
                     /gene="mdoG"
                     /locus_tag="LSX49_003253"
     CDS             complement(8314..9849)
                     /gene="mdoG"
                     /locus_tag="LSX49_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HBL7169631.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            10243..11400
                     /gene="mdoC"
                     /locus_tag="LSX49_003254"
     CDS             10243..11400
                     /gene="mdoC"
                     /locus_tag="LSX49_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706958.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HBL7169632.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEP
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNLRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            complement(11408..12889)
                     /gene="clsC"
                     /locus_tag="LSX49_003255"
     CDS             complement(11408..12889)
                     /gene="clsC"
                     /locus_tag="LSX49_003255"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsC"
                     /protein_id="HBL7169633.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADHIELPASWHNDVMTHRYLRKMESSPFIHHLVDGTLPLIWAKTCLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVKLASILPVEWLL"
     gene            complement(12831..13364)
                     /gene="ymdB"
                     /locus_tag="LSX49_003256"
     CDS             complement(12831..13364)
                     /gene="ymdB"
                     /locus_tag="LSX49_003256"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HBL7169634.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAHLYERLLTQQGDE"
     gene            complement(13459..13770)
                     /locus_tag="LSX49_003257"
     CDS             complement(13459..13770)
                     /locus_tag="LSX49_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7169635.1"
                     /translation="MFRPFLNSLMLGSLFFPFIAIAGSTAQGGVIHFYGQIVEPACDV
                     STQSSPVEMNCPQNGSVPRKTYSSKALMSGNVKNVQIASVKVQYLDKQKKLAVMNIEY
                     N"
     gene            complement(13891..14223)
                     /gene="csgC"
                     /locus_tag="LSX49_003258"
     CDS             complement(13891..14223)
                     /gene="csgC"
                     /locus_tag="LSX49_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HBL7169636.1"
                     /translation="MNALLLLAALSSQITFNTTQQGDMYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            complement(14283..14741)
                     /gene="csgA"
                     /locus_tag="LSX49_003259"
     CDS             complement(14283..14741)
                     /gene="csgA"
                     /locus_tag="LSX49_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HBL7169637.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNS
                     ELNIYQYGGGNSALALQADARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSA
                     TLDQWNGKDSTMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            complement(14782..15237)
                     /gene="csgB"
                     /locus_tag="LSX49_003260"
     CDS             complement(14782..15237)
                     /gene="csgB"
                     /locus_tag="LSX49_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HBL7169638.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGSANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
     gene            15990..16640
                     /gene="csgD"
                     /locus_tag="LSX49_003261"
     CDS             15990..16640
                     /gene="csgD"
                     /locus_tag="LSX49_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HBL7169639.1"
                     /translation="MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWP
                     HINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
     gene            16645..17034
                     /gene="csgE"
                     /locus_tag="LSX49_003262"
     CDS             16645..17034
                     /gene="csgE"
                     /locus_tag="LSX49_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HBL7169640.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            17059..17475
                     /gene="csgF"
                     /locus_tag="LSX49_003263"
     CDS             17059..17475
                     /gene="csgF"
                     /locus_tag="LSX49_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HBL7169641.1"
                     /translation="MRVKHAVVLLMLISPLSWAGSMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            17502..18335
                     /gene="csgG"
                     /locus_tag="LSX49_003264"
                     /pseudo
     CDS             17502..18335
                     /gene="csgG"
                     /locus_tag="LSX49_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
     gene            complement(18400..18891)
                     /locus_tag="LSX49_003265"
     CDS             complement(18400..18891)
                     /locus_tag="LSX49_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBL7169642.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLVFGYAMKNSGLWLAARSTKTAHREQQIK
                     NKA"
     gene            complement(18993..19547)
                     /gene="ycdY"
                     /locus_tag="LSX49_003266"
     CDS             complement(18993..19547)
                     /gene="ycdY"
                     /locus_tag="LSX49_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone YcdY"
                     /protein_id="HBL7169643.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMTQVSADYNALFIGDECAVPPYRSAWVEGATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDSEE"
     gene            complement(19571..20308)
                     /gene="ycdX"
                     /locus_tag="LSX49_003267"
     CDS             complement(19571..20308)
                     /gene="ycdX"
                     /locus_tag="LSX49_003267"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
                     /protein_id="HBL7169644.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKYQVALEINNS
                     SFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPER
                     ILNVSPRRLLNFLESRGMAPIAEFADL"
     gene            complement(20363..21301)
                     /gene="ghrA"
                     /locus_tag="LSX49_003268"
     CDS             complement(20363..21301)
                     /gene="ghrA"
                     /locus_tag="LSX49_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HBL7169645.1"
                     /translation="MDIIFYHPTFDTQWWIEALHKAIPQARVRAWKSGDNESADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRLQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVDYISRTIAQLEKGERVCGQVDRARGY"
     gene            21535..21622
                     /locus_tag="LSX49_003269"
     tRNA            21535..21622
                     /locus_tag="LSX49_003269"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21569..21571,aa:Ser,seq:gga)
     gene            complement(21727..23094)
                     /locus_tag="LSX49_003270"
     CDS             complement(21727..23094)
                     /locus_tag="LSX49_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBL7169646.1"
                     /translation="MEKDYLGISSTVLVSLLFGLALVLVNSWFNQPTVEEVVPRSTYL
                     MVMIALFFIDTVAFIFMQLYFIYDRRQFSNCILSLAFLSCLIYFVKTVIIIQQIIEGR
                     LTSSVVQNDIAIYYLFRQMSLCMLIFLALINKVSENTKQRNLFSKKVTLCISLFFVLG
                     GPIVAHIFSSHYESYDLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNDLRC
                     DIWNGVSVIAFCAVLYNISLLFMSRYSVSIWYISRTIEVVSKLTVLVIFMCHIFSALR
                     VTKDIAHRDPLTNIFNRNYFFNELTVQSASAKKTPYCVMIMDIDHFKKVNDTWGHPVG
                     DQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTEIDTECAKALAERIRENVERLTGD
                     NPEYAIPQKVTISIGAVVTQKNELNPKEIYQLADNALYEAKETGRNKVVVKEAEILIN
                     RKDDE"
BASE COUNT         6100 a         5787 c         5306 g         6064 t
ORIGIN      
        1 acttatgaag attctttcat tattaattca aaattattga aataaaaata aatatcattc
       61 aatttgttat ttttgtgttg caattcattc tccgacacgc cattttcttt ctctcgcaaa
      121 ttcgttttgg atgtacttat gtcattcaca aatacccctg aacgctatgg tgttatatct
      181 gcggccttac attggctaag cgcaattatt gtctacggca tgtttgcttt aggtctgtgg
      241 atggtcacgc tcagttatta cgatggctgg tatcacaaag cacccgaact gcataaaagc
      301 atcggtattt tgttaatgat ggggctggtt attcgcgttc tgtggcgtgt catatctcca
      361 ccgccgggtc cgctgccgag ttattcgccc atgactcgtc ttgcagcaaa agctggacat
      421 ctcgcattgt acctattgct gttcgccatc ggcatcagcg gctatctgat ctcaactgcc
      481 gatggtaaac cgatcagcgt ttttggctgg tttgacgtcc ccgcgaccct ctccgacgct
      541 ggcgcacagg ctgactttgc cggtgccctg catttttggc tcgcgtggag cgttgtagta
      601 ctgtccgtta tgcacggatt tatggccctg aagcatcatt tcatcgataa agacgacact
      661 ctgaagcgca tgctgggaaa gtcgtcatct gactatggag tataaaaaat gaaaaaaagc
      721 ctgcttggtt taaccttcgc ttccttgatg ttctctgccg gttcagcggt tgccgccgat
      781 tacaaaattg acaaagaagg tcagcacgcc tttgttaact tccgaatcca gcatcttggc
      841 tatagctggt tatatggcac cttcaaagat ttcgacggta cttttacctt tgatgaaaaa
      901 aatccagctg ccgataaagt gaatgtgaca attaacacca ccagcgtcga tactaatcac
      961 gccgaacgcg ataaacatct tcgcagtgcg gatttcctca ataccgcaaa atatccacag
     1021 gcaacattca cctccaccag cgtgaagaaa gacggtgacg aactggatat taccggcaat
     1081 ctgacgctga atggtgtaac caagcccgtc acactggaag cgaaattaat tggtcagggt
     1141 gacgacccgt ggggcggtaa acgtgcaggc tttgaggccg aaggcaaaat taagctcaaa
     1201 gacttcaata tcaagacaga tttaggtcca gcgtctcagg aagtggatct gattatttca
     1261 gtggaaggcg tacagcagaa gtaagagtga aatgttgccg gatggcacgc atccggcaat
     1321 gatatttatt ctgttggatc aggaatgccc agtgttgtat tcagacgtcc acgagactta
     1381 ttaaagatct tattgccatt ttcacgtcct gcccgacggc gtcgctgttc ctctggcggt
     1441 aacgcgcttt cttcgcagca aatctcacta caacaacctt tgtatttttc cgcacatact
     1501 ggacactgaa taaacagcag atggcagcca tcatttttac agttggtatg gctgtcgcac
     1561 ggcgcaccgc actggtggca gtgcgcgata atctcatcag atatacgttc gcccatccgc
     1621 tcgtcaaaaa caaaattttt gccaataaaa cgcaccggca agccctgctc gcgcgcctta
     1681 cgggcgtatt caataattcc gccctcgata tgccagactt tgttgaatcc gttatgtttc
     1741 atccaggcac tggccttttc acaacgaatg ccgccggtgc agtacatgac gattttttta
     1801 tctttatgtg cctgcatcat ctcaactgct tttggcagct gctcacggaa ggtatctgcc
     1861 ggtatttcca gcgcgttttc aaagtgcccc acttcatact catagtggtt acgcatgtcg
     1921 ataaacaatg catcgggatc gtcaagcatg gcgttcactt ccgccgcttg cagatactca
     1981 ccaacattgc tggcatcaaa gtgaggatcg tcaataccgt cggcaacaat gcgatcgcgt
     2041 accttcatac gcagtaccca gaaggatttc ccgtcatcat ccaacgcgat attcaggcgt
     2101 aaaccctcta aagccggatc gaaggcatag agctgtgcgc gaaatgtttc aacattgctc
     2161 gcaggtacgc tgatttgcgc gttaatgccc tcatgcgcca gatacactcg cccaaaaaca
     2221 ttcagcgcgg taaacagttg atataaagcg tcacgggtca ccttaggatc ggcaatgtgg
     2281 aaatacttat aaaacgaaat ggtggttcgc ggttcgctct cagccaacat tttggctttt
     2341 aacgcgtcgt tggaaatgcg gttgtgtaac actggcatgg tgtacggttc ctgcgagatg
     2401 ggaaagtaaa aatccgcggc atgatatagc aattatcgat aattaacatc cacacatttt
     2461 acgctacatt ttagcattaa aaattatttg ttatttacaa gcgcggcaat ttcgcccagt
     2521 cttcagtcac aaattttggt tgcggacgaa aaaatgcgac aatacataca attgcccgta
     2581 taggttgaaa aacaggattg atatgacgaa tctacccaag ttctccaccg cactgcttca
     2641 tccgcgttat tggttaacct ggttgggtat tggcgtactt tggttggtcg tgcaattgcc
     2701 ctacccggtt atctaccgcc tcggttgtgg attaggaaaa ctggcgttac gttttatgaa
     2761 acgacgcgca aaaattgtgc atcgcaacct ggaactgtgc ttcccggaaa tgagcgaaca
     2821 agaacgccgt aaaatggtgg tgaagaattt cgaatccgtt ggcatgggcc tgatggaaac
     2881 cggcatggcg tggttctggc cggaccgccg aatcgcccgc tggacggaag tgatcggcat
     2941 ggaacacatt cgtgacgtgc aggcgcaaaa acgcggcatc ctgttagttg gcatccattt
     3001 tctgacactg gagctgggtg cgcggcagtt tggtatgcag gaaccgggga ttggcgttta
     3061 ccgcccgaac gataatccac tgattgactg gctacaaacc tggggccgtt tgcgctcaaa
     3121 taaatcgatg ctcgaccgca aagatttaaa aggcatgatt aaagccctga aaaaaggcga
     3181 agtggtctgg tacgcaccgg atcatgatta cggcccgcgc tcaagcgttt tcgtcccgtt
     3241 gtttgccgtt gagcaggctg cgaccacgac cggaacctgg atgctggcac ggatgtccgg
     3301 cgcatgtctg gtgcccttcg ttccacgccg taagccagat ggcaaagggt atcagttgat
     3361 tatactgccg ccagagtgtt ctccgccgct ggatgatgcc gaaactaccg ccgcgtggat
     3421 gaacaaagtg gtcgaaaaat gcatcatgat ggcaccagag cagtatatgt ggttacaccg
     3481 tcgctttaaa acacgcccgg aaggcgttcc ttcacgctat taaatcttcc atgctggatg
     3541 cttcagaatg gcatccggca ttaccacaga aaatccccct gatttagcga taaaagctct
     3601 ctggattgcg ccccctggaa gtcgggcgca taattagtgt gcttatcttt tcttcttatg
     3661 ttcaccgcgc ctggcgcacc aacagcggat tgctatgtca ccctgtgaaa atgacacccc
     3721 tataaactgg aaacgaaacc tgatcgtcgc ctggctaggc tgttttctta ccggtgccgc
     3781 cttcagcctg gtaatgccct tcttacccct ctacgttgag cagcttggcg ttaccggcca
     3841 ctccgccctg aatatgtggt ccggtattgt cttcagcatt acatttttat tttcggccat
     3901 cgcctcaccg ttttggggtg gactcgccga tcgtaaaggc cgaaaactca tgctattacg
     3961 ctctgctctc ggcatgggca tcgtgatggt gttgatggga ctggcacaaa atatctggca
     4021 gtttttgatc ctgcgggcgc ttcttggttt acttggcgga tttgtcccca acgctaatgc
     4081 tcttatcgcc acacaagtac cgcgtaataa aagcggctgg gcgctgggta cgctctccac
     4141 aggcggcgtt agcggcgcgt tgctcggccc aatggctggc ggtttgctcg ccgatagcta
     4201 cggcttacgt ccggtattct ttattaccgc cagtgtgctc atactctgct ttttcgtcac
     4261 cctgttttgc atcagagaaa aattccagcc ggtcagcaaa aaagagatgc tgcacatgcg
     4321 ggaagtggtg acatcactta aaaacccgaa actggtactc agcctgtttg tcaccacgtt
     4381 aatcatccag gtggcgacgg gctcaattgc ccccattctg acgctgtatg tccgcgaact
     4441 ggcgggtaac gtcagtaacg tcgcctttat cagtggcatg atcgcctcgg tgccaggcgt
     4501 ggcggctctg ctaagtgcac cacgactcgg caaacttggc gatcgaatcg gacccgaaaa
     4561 gatcctgatt acggcgctga tcttttctgt actgctgttg atcccaatgt cttacgttca
     4621 gacgccattg caacttggga ttttacgttt tttgctcggt gccgccgatg gtgcactact
     4681 ccccgccgta cagacactat tagtttataa ctcgagcaac cagatcgccg ggcgtatctt
     4741 cagctataac caatcgtttc gtgatattgg caacgttacc ggaccattga tgggagcagc
     4801 gatttcagcg aactacggtt ttagggcggt atttctcgtc accgctggcg tagtgttatt
     4861 caacgcagtc tattcatgga acagtctacg tcgtcgtcga atcccccaga tatcgaactg
     4921 atttttcgcc tttcatactt gcaaaagcgg agaatcagct atccttttcc ctgaaacctc
     4981 atcaactcaa agggagaatc gtgatgacca tgtacgcaac gcttgaagaa gccattgacg
     5041 ctgcacgcga agaatttctt gcagacaacc ccggcatcga cgccgaaaac gcgaatgtgc
     5101 aacagttcaa tgcccaaaaa tacgttttgc aggacggcga catcatgtgg caagttgagt
     5161 tttttgccga cgaaggggaa gaaggtgaat gtttacccat gcttagcggt gaagctgcgc
     5221 aaagtgtctt tgacggcgac tatgatgaga tagagatccg ccaggagtgg caagatgaga
     5281 atacattaca tgaatgggac gagggggaat ttcagcttga gccaccgctg gataccgagg
     5341 aaggacgcac agcagctgat gagtgggatg aacgttaatc actcatacgg gccatgatga
     5401 atgtcgatcg gcagcagtaa ggtatcgaaa accagggaga atggcagatc aaggatcgtg
     5461 acgtaacgcc aggcggagtc acgcacgtcc cattgcacac cgggataata ttggttgcca
     5521 tgcccctgcc ccggtatagt gcgactaatg atgctgccac agccactcag caaggtcacc
     5581 attatgctca ccacaattaa acgcatttga tacctcttcc gtaaaaaata ccggcataac
     5641 gccggtattt ttattggctc gttgtttttg ccggatgcgg cgtgaacgcc ttgccagacc
     5701 cacaaaatct tgcaaaatca ataaattgca ggaacgatgt aggcctgata agcgtagcgc
     5761 atcaggcaac tacgttttta ttgcgaagcc gcatccggtt tacgcaatgc cagtggattg
     5821 agctttatcc cttcgtaata actcacccat gaagaatatc tctccgggga attccagacg
     5881 cggaaatgca gacgggccat cgtcaccgga tcgcttagca gcaccaggcg acgatcgcga
     5941 ttcagcttct ctggcgtctc gttcagcgcc tgttcaacgt ggcggtcacg ggcgatttcc
     6001 agcaccttgc tggcgcggtg acgcgcggtc gccattgcgg ttgccagagc gttaaatgac
     6061 gggttaaaca ccgcgtgcat aaaaccatca tcaagggagc gttgacgatt catctcaagg
     6121 aaccgatcgg tatcaaccag cacctgcggc ggtgaatact cttccgggat caggaacagt
     6181 ttccagcgtt tggttcgcag accaacggtg gcacggctgg aaatcaccga aacaaacggt
     6241 gacaggatca acgagaagac aatcggtgcc agccagaaca gaaaacgcag atccagccac
     6301 gccatcccaa cagcccacac taaccctaac agcagctgtg agccgtggcg tttgaacgct
     6361 tccccccagg aagtggagtc atcatcacgc tgcggcgaat tccacactac ttcccagcca
     6421 aggaacgcgc tgacgacgaa gaccgtatgg aacagcatgc gtaccggagc cagcagcacg
     6481 gaaaacagca cttccagcag caacgataat gtaacgcgcc agaagccgcc gtattctttc
     6541 gttcctttgc accagataag caaaatgctc aatagcttcg gcaggaacaa cagcaccatg
     6601 gtcgaagcaa aaagtgcaat cgccagctca ggacgccact gcggccatac cgggaacaac
     6661 tgccgtggtt gcaggaagta ttgcggttcg gtcaacgcat gtactacctg caatgcagta
     6721 gagagcgcga ggaacataaa ccacagcgga gcggagagat aagacatcac gcccgtcagg
     6781 aacaccgcac ggtgaaccgg gtgcataccc ttcaccagga acagacggaa gttcatcagg
     6841 ttaccgtggc accagcggcg gtcacgtttt agctcatcaa gcaagttagg cggcaattct
     6901 tcataagaac ccgggagatc gtaagcaatc cagacccccc aacctgcacg gcgcatcaac
     6961 gccgcttcca cgaagtcatg tgacaggatt gaaccggcaa aagaaccttc gcccggcagc
     7021 ggagccagtg cacagtgctc gataaacggt ttcacgcgga taatcgcgtt atgcccccag
     7081 tagtgcgact cgccaagttg ccagaagtgc aaaccggctg taaacagtgg cccatacacg
     7141 cgggtcgcga actgctgaca gcgcgcatac agcgtatcca tgccggacgc tttcggcgac
     7201 gactgaatga tcccggcgtt cgggttggct tccatcaggc gcaccaggcc gcacaaacaa
     7261 tcaccggtca ttaccgagtc agcatccagc accaccatgt agctgtactg gctgccccag
     7321 cgacggcaga agtcatcgat attaccgctt ttacgcttca cgcgacggcg gcggcggcga
     7381 tagaaaatct gaccttcgcc accgacttca gcgataagct ccatccaggc tttttgctct
     7441 gcgacgcaga tatccgggtt ataactgtca ctcagaatgt agacatcaaa gtgtttggca
     7501 ttcccggtgg cttttactga ttcccacgtt gcacgcaagc cagcaaaaac acggttcacg
     7561 tcttcgttac agataggcat gatcaacgcc gtgcgatgct ccgggtttaa tggttcatcg
     7621 ccaactgttg acgcagatat actgtattta tcgcgaccaa taagcagttg caggaagccc
     7681 atcaacgccg tccagaaccc ggcggacacc caacagaaca gtaccgcaaa gaggatcagg
     7741 ataccggttt gcagcatata aggcagaagc tgcataaagg aaacccacac atcctgacca
     7801 accatatcca taggattaat cagcgcccac ccctgataag gaagaatggt cttcatatac
     7861 caggtcgcga caacagtttg cgcgagcgtc aggatcaaca gaatgtaacg gcggatggta
     7921 ccgacggtac gccacttttg ctcactctcc tgctcttctt tggtcaaacg agccagatag
     7981 cgcggcgtca catcgcgtcc acgcaggcga tcccagaaac ggcctaccgg gttggtacgc
     8041 cacgggtcgg gaaacatcga ggagcgtttt gcttctggca tcgcctttag ctgatcgcgc
     8101 ccttcgtcgt ctttaattaa ctgtccatca gcaagtgaat ctggccaggc ttgttccaga
     8161 cgcgccttta ccgagccttg cggggagtca tcctcccgcg cccaggtgcg gtgttcggca
     8221 tccagcgcct gatgaacggc gcggatatca gtcttcggca atgccgcttt ctcgcttgcg
     8281 gcgatgggca ttgcgtcaat gtactcagtt gtcttattca ttggcaggta actggtagct
     8341 ccaggtttca ctcaacgtct gatcggcatt caccagcgca gcacgcattt cagtggtttt
     8401 cttggcatct ttcactttca cacgcatcac cagacgccaa cctttggtaa ccgggttata
     8461 gcgcaccgtg ctttcaacta tctcaccatt atcaccaatg ctggtttgcg ctgtgaccgg
     8521 ggtatcctct ggcagttttt tcatctcagc gccggtaaaa tcgaccacaa aggcgatagt
     8581 accgtcaggc tggcgaatca ggttcgactg cttcacatcc cccgttgaac gacgcgtttg
     8641 ttgcacccat gcgttatctg gcgcatgcag tttgtcttca tcacggctga aggtgatggt
     8701 gtatttaaag ttcatctctt tacccggctc cggcagctga tccggcgtcc agtaagcgac
     8761 gatgttatcg ttggtttcat cgttagttgg aatttccacc agctcaacgc tgcctttgcc
     8821 ccactcccct ttcggagtca cccatgcgct tggacgaaga tcgtaacgat catcgagatc
     8881 ttcaaagcgg gagaaatcac gaccgcgctg caacagaccg aagccttgcg ggttttccat
     8941 cgagaagctg ctgacagcta aatgtttcgg gttattcaac ggacgccaga tccattcgcc
     9001 attaccagca tggatagaca gaccgttaga gtcgtgcaac tccggacgat agttatttgc
     9061 aggcgacggt tggttcggcc caaacaggaa catactggtt aacggtgcaa cccccagttt
     9121 gccgacttta tcgcgcagat agattttcga ctgcacatcc acaaccgtgt cacgtcctgg
     9181 cataactacg aatttgtaag cacctgtcgc gcgcggcgag tcaagcaatg cataaatggt
     9241 taaacgttta tcagtcggtt ttggacgctc gatccagaac tctttgaagc gtggaaattc
     9301 ttcacccgat ggcaaggcgg tatcaattgc caggccgcgt gcagaaaggc cataaacctg
     9361 acctgcacca atcacgcgga aatagctggc cccgagcatg ctgacgattt catcgttttt
     9421 atctttgctg ttgatcgggt aaagcacttt gaaaccggca aaaccaaggt cttttaccgt
     9481 gtctttgtca tgctgaacat cgccgaaagt gaaataatcc gggctgtatt tgattcgttt
     9541 gactgcggtg gcagtcactt catttatttt gaccggggta tcgaagtaca taccctgatg
     9601 gtagaactcg agtttgaatg gggtcttcag attgttccag tacgctttgt catgattaaa
     9661 ctggatctgc tgatagtccg cgtatttcat atcgcggaaa acggagggca agttgctttt
     9721 gggcgcctca tagcctttcc cggctaagga ttgagcttgc tttgcgacat catcaatact
     9781 gaaagcccag cttgaagatg tatacagggt taacattact gcagcactca accaacgcat
     9841 tttcatcatt tgtagtttat gtttcataat tagtaagcac ttcccccttt gtgtgcttat
     9901 atcgatccga tctattttaa tggataacct gccattccga caacagaatc ccggtatcgt
     9961 tcagcacact ggctcatgga ttaagcacct gattgcaacc gttttcactt tccgtgcttc
    10021 tcctaaagac agaagcatcg acttcgtgta gggtttgcca gcaaatttat ttatcaaccg
    10081 tcttacagac gcttccattc tggttagtgg tagcgatgat gctatgcata aaaaccttga
    10141 agcctgcgcc tggcgcggtc aggtcggtgt cactatggca acaagcctaa aggcataacc
    10201 cgacagggat aagacgaaaa atctgagatc agttaaccat atatgaatcc agtacccgcg
    10261 caacgtgaat atttcctcga ctccatccgc gcctggctga tgttgttagg gatccctttt
    10321 catatttctt taatctattc gagccataca tggcatgtga atagcgccga gccgtcattg
    10381 tggctgaccc tttttaatga cttcatccac tcgttccgca tgcaggtgtt tttcgttata
    10441 tccgggtact tttcctacat gcttttttta cgctatccct tgaaaaaatg gtggaaagta
    10501 cgtgtcgaac gtgtaggtat cccgatgtta acagccatcc ccttactgac attgccgcaa
    10561 tttattatgc tgcaatacgt caaaggcaaa gcggaaagtt ggcctgggct gtcattgtat
    10621 gacaaatata atacgttggc ctgggaatta atatcacacc tgtggttttt actggtgtta
    10681 gtggtcatga cgacgctgtg cgtatggata tttaaacgca tcagaaataa tttagaaaat
    10741 tctgataaaa cgaataaaaa attctcgatg gtaaaattat cggtgatttt tttgtgcctc
    10801 ggcatcggtt atgcggtaat aagaagaacg atttttattg tgtatccacc cattctgagt
    10861 aacggcatgt tcaattttat tgtcatgcaa acgttatttt atttgccgtt ctttatcctc
    10921 ggcgcactgg ctttcatttt ccctcatctt aaagccttgt ttaccacgcc ttctcgtggc
    10981 tgtacccttg cagcagcatt ggcgtttgtc gcttatttac tcaacctgcg ctatggcagt
    11041 ggcgatgcct ggatgtatga aaccgagtcg gtgatcacca tggtcctcgg tctgtggatg
    11101 gtgaatgtgg tcttctcctt tggccaccgt ttgcttaact tccagtcagc gcgggtgact
    11161 tattttgtta acgcatcgct gtttatctat ctggttcacc acccgttaac gctgtttttc
    11221 ggcgcataca ttacaccaca catcacctcc aactggcttg gttttctctg tggcctgata
    11281 ttcgtagtag ggattgcgat aattctgtat gaaattcatt tacgcatccc attattgaag
    11341 tttttgttct ctggtaaacc ggttgttaag cgtgagaacg ataaagcacc tgcccgttaa
    11401 gccgcgttta caataaccat tccacgggca atatcgacgc cagtttgacc ataacccgct
    11461 tccagaaact ggtggcgggt tcttttttga gaataatctc tttctttgca tgacgatcaa
    11521 cccagttgat ccgtccccac ctgtccagac ggagctgcca ggccgcatca tactggctct
    11581 gaataaagcg tttatcaatt aactgtgcca gcgtttcgct ctctatcacg aagcccattt
    11641 cagtattgag caatgttgaa cgcggatcga aattgaaaga gccaataaac accgttttac
    11701 catcgatgct aaaggtttta gcatgcaggc tggcaccgga attaccggtt ataccgcgat
    11761 cgtgtaatgt actactttgt tcacgcgtcg gcttgagttc atataattcc accccatagc
    11821 gaagcaattt tttgcgccag cgcgcgtatc cggcatggac gacagcaaca tcgttagcgg
    11881 caagagaatt ggttaggatc gcaatcttta ccccttttct caccatccgt aagagttgcg
    11941 ccacacctgc acgtgtcggt acaaaatagg aagagataat atcgatgcgt tcactgggtg
    12001 agcccatgat atcgaacagg cgctgcggta acagtgaatg ccgttttgcc ttgccctccc
    12061 ctttcgccgg atcatcactt aataaacatg ttttcgccca gataagcggc aacgttccat
    12121 caaccagatg atgtataaac ggactggatt ccattttgcg taagtaacga tgcgtcatga
    12181 catcgttatg ccaggaggcg ggtaactcga tgtgatccgc catttcacct tccgggacat
    12241 ccagcacctg ctgtaagggg gaaaccgatt tgcaatacca gtagcgggcg aaatcatcgg
    12301 caacgtcctc taccacgggt cctattgcca tgacatctaa atccgaaaaa agtggctctt
    12361 cccctgcccc aaaataggca tcaccaatat ttcgtcctcc caccagcgtc accacgccat
    12421 cgacagtgaa acttttattg tgcatacggc gattgagacg ggaaaagtcg gtgatataac
    12481 caagcggacg tagcaaacga aacgagaaag gattaaaaag ccggacttca atgcgtggat
    12541 ggctgtcaag caagcgtaaa atgtcatcaa gtccgggcgt attgttgtcg tccagcaaca
    12601 aacggacgcg aacgccacgc tttgctgcgg ctaacagggc ggaaaacagt aaccgacccg
    12661 acatatcgtc ctgccagatg taatactgaa catccagcgt atgctctgcc atttcagcca
    12721 gacgataccg ggcggcaaac gcatccagac ttttctccag aggaaaaagt ccacactgac
    12781 cgggatgttg cgaacacagt ggcagcaccg cgctcgccag ccgaggcaaa tcattcatct
    12841 ccttgttggg taaggagtct ttcgtagagg tgggcgtttt cttcatcata acagacaaag
    12901 tatacctgtt cgggtaaagc gtgacgggta ataaattctg aaacggtttt tactgcgatt
    12961 tcagccgctg ccgcacgggg ataaccataa accccagtac tgattgcagg aaaagccact
    13021 gacgtatagc tgtttgccgc caccagtcgt aggctattga gataggcatc ctgcaaaagc
    13081 tggtcttcgt tttgttcacc accacgccag actggcccga cggtgtgcac tacggcttta
    13141 gcgggaagat cgcctgcaag cgtaataacg gcatgccccg tagggcaatc gccctgctgc
    13201 tgcctgactt ttaaacaggc atccagcagg gccggacccg ctgcgcgatg aatggcccca
    13261 tcgacgccgc cgcctcccat taatgacgga ttagccgcat tcacaatcac atcaacggcc
    13321 agtttggtaa tatcaccctg cacaacatga atacgcgttt tcataacgcc tccttacacc
    13381 ttcttgtttc ctaagtgtac agcaggcttt ttagttaaat cgcatttttc tgcttagcaa
    13441 cgtgagttgt tcagaaactt agttatattc gatgttcatt acagccagct ttttctgttt
    13501 atcaagatac tgcactttta ctgaggctat ttgcacgttt ttaacattgc cgctcattaa
    13561 ggctttgctg gaataggttt tacgcggaac agaaccattc tgtgggcagt tcatttctac
    13621 gggtgatgac tgggtgctga cgtcacatgc cggttccaca atttggccat aaaaatggat
    13681 cacgccccct tgcgcggtgc ttcctgcaat ggcaataaaa ggaaaaaaca aactgccgag
    13741 cataagagag tttaaaaaag gtctgaacat ttattctatt tcctcaatga ttagtcatcc
    13801 ttgagggttg tgttatccat actttcaggt tggctgattc gcagcagacc attctctcca
    13861 ggttcatctt atgctcgata tttcaacaaa ttaagacttt tctgaagagg gcggccattg
    13921 ttgtgataaa tgaagtgact gtccatcaga aacagtaaca actattttca cccgatcgtc
    13981 cggggaaata tttaaactca acttcgtcaa agcaatgggt tgattagcag gcaatgagag
    14041 ggtcttttct tgcttcgtct gactttgccc tgaactgcct tcgcgcaggg acaatatttg
    14101 tactctgcac agacaagatt gagtaagagt gacttcagga ataatggtgt acatatcccc
    14161 ttgctgggtc gtattaaagg ttatctgact ggaaagtgcc gcaaggagta ataacgcatt
    14221 catattcttc tcccgaaaaa aaaacagggc ttacgccctg tttctttcat acagatgatg
    14281 tattagtact gatgagcggt cgcgttgtta ccaaagccaa cctgagtgac gttaacgctg
    14341 gagttagatg cagtctggtc aacagcagca ccgttaccgc caccgaactg tttaacagtc
    14401 atagtagaat ctttaccatt ccactgatca agagtagcgc tgttgccgaa accacgctga
    14461 gtcagatcga ttgagctgtc atcagaacct tggccaacat ctgcaccatt accgccgccg
    14521 tgctgggtaa tggtcagatc agagttgcgg gcgtcagctt gcagagcaag agcagagtta
    14581 ccgccaccgt actggtaaat attcagctct gaattcgggc cgctgttatt accgccacca
    14641 ccgtggttgc cgccaccgcc gccgtactga ggaacaacac ctgccagagc gctaccggag
    14701 aatacgattg ctgcaattgc tgctactttt aaaagtttca tgtaaaaccc ccatcggatt
    14761 gatttaaaag tcgaatggaa attaacgttg tgtcacgcga atagccattt gcgactgtct
    14821 ctgcactaca attgccgttt tttgagtacc atactgtgta atatttgctt tattaccaga
    14881 acctttctgg ataatcatcg cagtattacc ataagcacct tgcgaaatac tggcatcgtt
    14941 ggcactgccc gcctgatcaa tatatgcaag gttataatct cctgtctggt caatctttgc
    15001 ccggttgcta ctaccttctt gcgcaacaac cgccaaaagt tttgagcctc cctgccgtaa
    15061 ctgagcacta ttattagtcc cagcttgacc aattatggct gcctgattaa atgaagactt
    15121 actcaattca tttaccgcaa agttatattc tgaattagct aaatcataac ctgctgcggc
    15181 tgcaatccca ggcgcaccca gtattgttaa catcataaat aacaatttgt ttttcatgtt
    15241 gtcaccctgg acctggtcgt acatttaaga aattaaatca tttcaacttg gttgttaacg
    15301 caacccgtat tttgttaacg ctgcgttacg atggaaagta tgtctgcgga aatattttta
    15361 ataactcacc cgcgcgttgt atttttcttt ttttgttcat accaaagtat taaaacccac
    15421 gtaaatacgc tgttatctac gcaaaaaata ttttgttttc ttttaaatct ccgttttccg
    15481 ctatcaaaaa tcaccagaca gtcattcttc ttgcccgtcg ctgattgctg cgatatgtct
    15541 tgcgcacaag ccgtgacaaa cctcgtcttt ttgcagtaaa aaattgtcca cggtggtatg
    15601 gagaaaaaac aagaacgttt tacatgacga aaggactaca gcgaaatatt ttttatatgc
    15661 attattagta agttagcacc atttgtatga ttttttaaaa ttgtgcaata aaaaccaaat
    15721 gtacaacttt tctatcattt ctaaacttaa taaaacctta agattaacat tttaatataa
    15781 cgagttacat ttagttacat gtttaacact tgatttaaga tttgtaatgg ctagattgaa
    15841 atcagatgta atccattagt tttatatttt acccatttag ggctgattta ttactacaca
    15901 cagcagtgca acatctgtca gtacttctgg tgcttctatt ttagaggcag ctgtcaggtg
    15961 tgcgaacaat aaaaaagcgg ggtttcatca tgtttaatga agtccatagt attcatggtc
    16021 atacattatt gttgatcact aaaccttctt tgcaagcgac agctctcttg cagcacctta
    16081 aacaatcgct ggcgattaca ggaaaattac ataatattca acgttctctg gacgatatat
    16141 cttcaggctc tattattctt ctggatatga tggaagcgga taaaaagctt atccattatt
    16201 ggcaggatac tttgagcagg aaaaacaaca atatcaaaat attgttgcta aatacgcctg
    16261 aagattaccc gtaccgcgac attgaaaact ggcctcatat caacggcgtt ttttatgcca
    16321 tggaggatca agaacgtgtt gtcaatgggt tgcaaggcgt cctgcgcggc gaatgctact
    16381 ttacgcaaaa gcttgccagt tacctgatta cgcattcagg taactatcgt tataacagca
    16441 cggaatcagc cctccttact catcgggaaa aagagatcct gaataagctg cgtatcggcg
    16501 cgtctaataa cgagatcgct cgttcgttgt tcatcagcga aaatacggtt aaaacgcatc
    16561 tttataatct tttcaagaag atagccgtaa aaaaccggac acaagcggtt tcctgggcaa
    16621 acgataacct caggcgataa agccatgaaa cgttatttac gctggattgt ggcggcagaa
    16681 tttctgttcg ccgcagggaa tcttcatgcc gttgaggtag aagtcccggg attgttaact
    16741 gaccatactg tttcatctat tggccatgat ttttaccgag cctttagtga taaatgggaa
    16801 agtgactata cgggtaactt aacgattaat gaaaggccca gtgcacgatg gggaagttgg
    16861 atcactataa cggtcaatca ggacgttatt ttccagactt ttttatttcc gttgaaaaga
    16921 gacttcgaga aaactgtcgt ctttgcactg attcaaactg aagaagcact aaatcgtcgc
    16981 cagataaacc aggcgttatt aagtacgggc gatttggcgc atgatgaatt ttaaataata
    17041 aattgttcgg aggctgcaat gcgtgtcaaa catgcagtag ttctactcat gcttatttcg
    17101 ccattaagtt gggctggatc catgactttc cagttccgta atccaaactt tggtggtaac
    17161 ccaaataatg gcgctttttt gttaaatagc gctcaggcac aaaactctta taaagatccg
    17221 agctataacg atgactttgg tattgaaacg ccatcagcgt tagataactt tactcaggcc
    17281 atccagtcac aaattttggg tgggctactg tcgaatatta ataccggtaa accgggccgc
    17341 atggtgacca acgattatat tgttgatatt gctaaccgcg atggtcaatt gcagttgaac
    17401 gtgacagatc gtaaaaccgg acaaacctcg accatccagg tttcgggttt acaaaataac
    17461 tcaaccgatt tttaagcccc agcttcataa ggaaaataat catgcagcgc ttatttcttt
    17521 tggttgccgt catgttactg agcggatgct taaccgcccc gcctaaagaa gccgccagac
    17581 cgacattaat gcctcgtgct cagagctaca aagatttgac ccatctgcca gcgccgacgg
    17641 gtaagatctt tgtttcggta tacaacattc aggacgaaac cggacaattt aaaccctacc
    17701 cggcaagtaa cttctccact gctgttccgc aaagcgccac ggcaatgctg gtcacggcac
    17761 tgaaagattc tcgctggttt ataccgctgg agcgccaggg cttacaaaat ctgcttaacg
    17821 agcgcaagat tattcgtgcg gcacaagaaa acggcacagt tgccattaat aaccgaatcc
    17881 cgctgcaatc tttaacggcg gcaaatatca tggttgaagg ttcgattatc ggttatgaaa
    17941 gcaacgttaa atcgggcggt gttggggcaa gatattttgg gatcggtgca gacacgcaat
    18001 accagcttga tcagattgcc gtgaacctgc gtgtcgtcaa tgtgagtacc ggtgagatcc
    18061 tctcctcggt gaacaccagt aagacgatac tttcctatga agttcaggcg ggggtcttcc
    18121 gctttattga ctaccagcgc ttgctggaag gggaagtagg ttaaacctcg aacgaacccg
    18181 ttatgctgtg cctgatgtcg gctatcgaaa caggcgtcat tttcctgatt aatgatggta
    18241 tcgaccgcgg cctttgggat ttgcaaaata aaacagaacg gcagaatgac attctggtga
    18301 aataccgcca tatgtcggtt ccaccggaat cctgatagat aaaaacgccg gaattaataa
    18361 tccggcattt tactgtttaa gcgaaagcgt gagtgcccct cacgctttat ttttgatttg
    18421 ctgctcacgg tgagcggtct tcgtactacg cgccgccagc cacaggccgc tgtttttcat
    18481 tgcgtaacca aataccagtc caagcgccag cgaaggtaac accagtttcc agtccccctg
    18541 cccggcaaac gtcgcgcatg cgcctataaa cgtccccgga acaaatgaaa gcagcagctg
    18601 tttggcctga atacacatca gaaacgcgac aataccggtt attacataac cgagaatttc
    18661 cagatgtggt gccagtgcac taccgtaaat aatgaccatc gcccacacca cgccactaag
    18721 cagggttgca gcggagatcg ccagcccttt cagcccacct tgcgggcagg caaagtaggc
    18781 cgtacagccc aggaagcccg cccagcttag taagcccagg gaaacagcca cccatcccca
    18841 gataccggag agaatgcctg ttgtgattgc aatagagaga agtatgttca tgccgcgcat
    18901 gatagcagaa aacgcggcca tgaatgagat cgagcacaca ttttatgcaa caacaaatta
    18961 tcagttgcag ttatgagtga tgcagatcac atttactctt cagaatcttc ttccagctcg
    19021 tcccacattg cactaatagc atcgcgggtt agcggtgcca tggtgcgcca gaaaggcgta
    19081 gttgcatggg cctccacttt gccaaggaac gcaccacacc agggtaacag atactcactg
    19141 aacagtgttt ccagtgcttc gctctcatct tccgttgact gatcttccag ccaggaagcc
    19201 gcaagcagca atgtgccgat gtgatcggct ggcgtatccg ctagtggcat ccctcgttcg
    19261 gaaagaaaag cgcgcacttc cgcttccgtt gcgccctcaa cccatgcgct acgatatggc
    19321 ggcacagcac attcatcgcc gataaacaac gcattgtaat cggcagagac ttgcgtcata
    19381 tcacagcttt tctgtaaacg cgtcagtaac tcatcctgct ccagtggcca gttcgcagcc
    19441 agtttcccct cacgaatcag ggtaaacaac ggcaccagta aaggatcttg cggttggcgg
    19501 taatagagcg aacccagcac acgacagagg atagaaaact cgttcattaa tatatttcca
    19561 ttactagtaa ttaaaggtct gcaaattccg caatcggtgc cataccgcga gattcaagga
    19621 agttcagtaa gcggcgcgga gaaacattca aaatgcgttc tggcggaaaa tctaccgcgt
    19681 cgaggatttt aagacactct tcaaattccc ccatggtaaa tgcagtgtga gaatccgagc
    19741 ctaatgccac ccaacctcca gcgtcacgta ccgctgcagc taccgcacga cagttgtctt
    19801 cactgccctt acgtgagtgt aaaaatgagg aattattgat ttccagcgcc acctgatatt
    19861 tcgcggctgc ttcagcaacg gctttaacat ctatctcata tttcggattt ccgggatggc
    19921 ttattatatg cacattgccg ctggcgatag tggcgatcat cgcttgtgta ttggttgctt
    19981 tgtcatgtgg cgcaaaaacc ggctcatgaa aaccggcaat aatcagatcc agcgaatcaa
    20041 acattttgcc gctgcaatca atttcaccat caacattttt aatgttagct tcgatgccgc
    20101 gcaggatccc taccccatca accactcgcg gccagatacg catgttaatg aagtgccagt
    20161 gatgcggcgc atcttccata tccgggccat gatcggtgat cgcaaaaagt ttaatgccct
    20221 tttgtttggc ctgggcaatg taatcactca atgtgctata tgcatgcgtg ctggcaacgg
    20281 tatgcatatg aaggtcgacg ggatacataa ctctctcctg tattcaattc ccgccaagga
    20341 tagcaggaaa cctgatgctt tattagtagc cgcgtgcgcg gtcgacttgc ccgcagaccc
    20401 tctccccttt ttcgagctgg gcaatggtgc gcgaaatgta atccacagct tcagcgggac
    20461 gggtaatcgc ggcgacatgt ggtgttatcg tcacgcgtgg atgttgccag agcggacttt
    20521 ccggcggtaa gggttcacga ttaaaaacat ccagcattgc gcctttaact ttgccgctat
    20581 ccagcgccgc gagcaggtca tcttccacga catgaacacc acgcgccagg ttgaggagat
    20641 acgcgccatc cggtaatttt tcgagtaatt gttgattaat aatgccgacg gtttcagggg
    20701 tattcggtaa caaattaatc aatacccggc attggctcag aaatgcagaa agttcttccc
    20761 gtccggcaaa gctttgcacg ccaggccacg atttacgggt tcgactccag caacgcagcg
    20821 ggaagcgcca ggtttgcaga ctctgtgcaa ctttactgcc cagtacgcct gcgcccaaaa
    20881 tgccgatggt aaaatcttcc cgatgatatt caggcagcgg ttgccaatgc gaactatttt
    20941 gctggaggcg gtaatcgtca aaacgtcgaa accaatgcag cacctgactg acagcatatt
    21001 cctgcatttg ctcgcccata ccggtatctt ccaggcgaaa aagtggaaca gaaggcttca
    21061 gcatttcagg gtgagcctgt agcttgctca aaatagaatc aacacctgcc ccaagtgcaa
    21121 acaccgcttt aagatcgcgc cctgccagca tttcaacagg aggatgccag actaaagcat
    21181 aatcggctga ttcattgtct ccgcttttcc atgctctgac tcttgcctga ggaatagctt
    21241 tgtgcagtgc ctcaatccac cattgggtat cgaacgttgg gtgataaaag atgatatcca
    21301 tactgactcc cgaaaagcgt tgcgcgaaat ttattcgcac ttatcgttat gatctacaaa
    21361 ggccaccagc ataacaaatc cgtggtcggt gacaaaaaaa gcaaatttcg cttattaaaa
    21421 ctacatattg attgaagttt gaataatcga gcgatttttt aaaaaagttt gttgacctca
    21481 ggtcatgatt tccctaaatt agcgcccgtt ccagcaagac aggaacgaca atttggtgag
    21541 gtgtccgagt ggctgaagga gcacgcctgg aaagtgtgta tacggcaacg tatcgggggt
    21601 tcgaatcccc ccctcaccgc catatttaaa gaagagctcg tacgaaagta cgagcttttt
    21661 tttcgtatat tgcatacacc ggggggatga gaagccccag gcggaggttg acaactagcg
    21721 acagactcat tcatcatcct tgcggttgat aagaatttct gcctctttta ctaccacctt
    21781 attacgcccg gtctctttcg cctcgtaaag tgcgttatca gccagttgat agatctcctt
    21841 agggtttaac tcatttttct gcgttacaac agcgccaata ctaatcgtca ctttttgtgg
    21901 tatggcgtat tcaggattat cgccagttaa acgttcaaca ttttcccgaa tcctttccgc
    21961 taaagctttc gcacattcag tatcgatctc cgtcagcaag acgccaaact cttcgccgcc
    22021 aacgcgcgct aaaaggtcat ctggtcgtat gcttttccca atgatattca ccactgtctt
    22081 tatcacttga tcgccaaccg gatgtcccca ggtgtcgttg acttttttga agtggtcaat
    22141 atccataatc atgacgcaat aaggtgtttt tttggccgat gctgattgaa ccgtcagttc
    22201 attaaaaaaa taatttctgt tgaatatatt ggttaaggga tcgcgatgtg caatgtcctt
    22261 tgttactcgt agcgcactga atatatggca cataaaaatt accaaaacgg ttaacttact
    22321 gactacttca atagtgcgac taatatacca aatggacacg ctatacctgc tcataaataa
    22381 cagagagata ttgtacagca cggcacaaaa agcaatcacc gacaccccgt tccagatatc
    22441 acagcgtaaa tcattaaagt atagattaac cgaaagcaag gttaaccaca tgaaaatcat
    22501 tatggtaaca tatgaggctt tccaaaccac ctgaccattt tcattggtta actcggcaat
    22561 gtgtaaatcg tagctctcat aatggctaga aaatatgtga gcaactatcg gccccccaag
    22621 aacaaaaaac aaacttatgc acaaagtcac ttttttggaa aataaattgc gctgttttgt
    22681 gttttcacta actttattta tcaatgccag aaatattaac atgcacaaac tcatctgacg
    22741 aaacaaataa taaattgcaa tgtcattttg aacaacactg cttgtcaaac gcccctcaat
    22801 aatttgctga atgataatga cggttttaac aaagtaaatc aaacaactta gaaaagccaa
    22861 actaagtata cagtttgaaa attgcctacg gtcataaatg aaatacaact gcataaaaat
    22921 aaatgcaaca gtatcgataa aaaataaagc aatcataacc atcagatagg ttgatcgtgg
    22981 aacaacttcc tcaacggttg gctgattgaa ccaactatta accaaaacca atgcaagccc
    23041 aaacaataag ctcactaata cagtactact aattcccaaa tagtcttttt ccataaagct
    23101 acaccaacct gtaggttgta gatccctttt tattattaat agatataaga actgtactgt
    23161 tgtcaatatg aaaatccacc cacaaacaat accgatgatg atagttgcag aatgcaatta
    23221 ttatcacttt aatgctttat acattttttg ctgcaag
//
LOCUS       DAFGPF010000075        23026 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFGPF010000075 DAFGPF010000000
VERSION     DAFGPF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23026
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.075"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            137..988
                     /locus_tag="LSX49_003271"
     CDS             137..988
                     /locus_tag="LSX49_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBL7169647.1"
                     /translation="MLKYSKTPGIFKLEGNRLGRPYHRLPTLFTGNFDVIDSHLGSYF
                     LKKHRSNITLKKIGCEMDIINKNAELMVSQVGHLAFDIDRSLLLMLLGNFYGLESSLE
                     EAKSHNGFPTKTETRLKNRLALDICTLIFNLQTSGIALKLKLDSSTVITHWAYQLTFT
                     LAGDEESSFRILLDDAHTDFILNLIRHSEHSKPQQVAKSVNKPALIKEIIRSLPLTLN
                     VKIAELSMNVADLAQIKAGDILPISLGETFPVAIGQSELFSALIVEDKDKLFLSELAG
                     KNENNHE"
     gene            981..1352
                     /locus_tag="LSX49_003272"
     CDS             981..1352
                     /locus_tag="LSX49_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBL7169648.1"
                     /translation="MSKQEDILAGDFGLTDEVAPVAKSADAETLVTRLEDRFSDSMTL
                     LKRIPVTLTLEVSSVEIMLADLLNIDDDTVIELDKLAGEPLDIKVNNILLGKAEVVVV
                     NEKYGLRVLEFNTRDINDLAP"
     gene            1349..2101
                     /gene="fliP"
                     /locus_tag="LSX49_003273"
     CDS             1349..2101
                     /gene="fliP"
                     /locus_tag="LSX49_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538309.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBL7169649.1"
                     /translation="MKRRTQLTLGLALLALAPLALAQGGDIALLNVVTHGNTQEYSVK
                     IQVLILMTLVGLLPTMVLMMTCFTRFIIVLSLLRQALGLQQTPPNRILIGIALSLTLL
                     VMRPIWLNIYDHAVVPFENDQITLTDALSTAATPLKRFMLAQTDKKAMAQIMTIGGAK
                     GNAADQDLSIVVPAYVLSELKTAFQIGFMIYIPFLVIDLIVASVLMAMGMMMLSPLIV
                     SLPFKLMLFVLIDGWSLTIGTLTTSIRGLGLG"
     gene            2104..2376
                     /gene="fliQ"
                     /locus_tag="LSX49_003274"
     CDS             2104..2376
                     /gene="fliQ"
                     /locus_tag="LSX49_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliQ"
                     /protein_id="HBL7169650.1"
                     /translation="MLTVDVAADIVASGIKVVILLVSVLVVPSLLVGLLVSVFQAVTQ
                     INEQTLSFLPRLIVTLVVLGVCGKWMIIQLHDLCIHLFTQAALLVH"
     gene            2378..3160
                     /gene="fliR"
                     /locus_tag="LSX49_003275"
     CDS             2378..3160
                     /gene="fliR"
                     /locus_tag="LSX49_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliR"
                     /protein_id="HBL7169651.1"
                     /translation="MRTSDVTQLMDLALGLWFPFVRIMAFLRYMPVLDNSALTARVRI
                     ILSLALAIIITPLIPHPIPHNLLSLNSLILTVEQILWGMLFGLMFQFLFLALQLAGQI
                     LSFNMGMSMAVMNDPSSGASTTVLAELINVYAILLFFAMDGHLLLVSVLYKGFTYWPI
                     GNALHPQTLRTIALAFSWVLASASLLALPTTFIMLIVQGCFGLLNRIAPPLNLFSLGF
                     PINMLAGLVCFATLLYNLPDHYLHLANFVLQQLDALKGHYGG"
     gene            3150..4289
                     /gene="flhB"
                     /locus_tag="LSX49_003276"
     CDS             3150..4289
                     /gene="flhB"
                     /locus_tag="LSX49_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HBL7169652.1"
                     /translation="MADSSSEEKTEKPSAQKLRKAREEGQLPRSKDMGLAASLFAAFV
                     VISSSFPWYADFVRESFISVHQYAQEINNPQVIGQFLRHHLLILGKFILTLLPMPAAA
                     LLSSLVPGGWLFLPKKILPDFSKISPLKGIGRLFSSEHLAETGKMTVKSVVVLVMLWV
                     SLRNNFAAFLSLQALPFKLAINDGLSLYASVMRNFVILFIFFALIDVPLAKALFTKGL
                     KMTKQELKEEYKNQEGKPEVKARVRRLQRQLAMGQIRKVVPKANVVITNPTHYAVALQ
                     YDQSRAAAPFVVAKGTDEIALYIRQVATENQVEVVEFPRLARSVYYTTQVNQQIPFQL
                     YRAIAHVLTYVLQMKHWREGAQPRPALNRHISIPKEVLKLDGENN"
     gene            4273..6366
                     /gene="flhA"
                     /locus_tag="LSX49_003277"
     CDS             4273..6366
                     /gene="flhA"
                     /locus_tag="LSX49_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBL7169653.1"
                     /translation="MAKTTKSFLALLRGGNLGVPLVILCILAMVILPLPPALLDILFT
                     FNIVLAVMVLLVAVSAKRPLEFSLFPTILLITTLMRLTLNVASTRVVLLHGHLGAGAA
                     GKVIESFGQVVIGGNFVVGFVVFIILMIINFIVVTKGAERISEVSARFTLDAMPGKQM
                     AIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGG
                     VCIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDV
                     RNQLLASPSVLYTATGIMFVLAVVPGMPHFPFLMFSALLGFTGWRMSKRPQAAEAEEK
                     SLETLTRTMTETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQV
                     ISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDG
                     VLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDI
                     TQLHNRLSSMAPRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVT
                     KDHILLAADVRLALRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQGGKVMLDS
                     VPVDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYN
                     EVPDELELKIMGALM"
     gene            complement(6586..7083)
                     /gene="rayT"
                     /locus_tag="LSX49_003278"
     CDS             complement(6586..7083)
                     /gene="rayT"
                     /locus_tag="LSX49_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="REP-associated tyrosine transposase RayT"
                     /protein_id="HBL7169654.1"
                     /translation="MSEYRRYYIKGGTWFFTVNLQNRRNQLLTTQFQTLRNAIINVKR
                     DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
                     IRNTQDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAEDVTDFSAG
                     ERIIL"
     gene            complement(7259..8008)
                     /locus_tag="LSX49_003279"
     CDS             complement(7259..8008)
                     /locus_tag="LSX49_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000093946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL7169655.1"
                     /translation="MSSFLHGRFLHPGVFSLCVLLPLLASATTSHISFSYAARQRMQN
                     RARLLKQYQTHLKKQASYIVEGNAKSRRALRQHNREQIKQHPEWFPAPLKANDRRWQA
                     LAENNHFLSSNHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVFYAYNKILE
                     AKLPRTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRT
                     GETIRVSRLAEPFWQDHFLGARRILTEETIL"
     gene            8320..9060
                     /locus_tag="LSX49_003280"
     CDS             8320..9060
                     /locus_tag="LSX49_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HBL7169656.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(9031..9798)
                     /locus_tag="LSX49_003281"
     CDS             complement(9031..9798)
                     /locus_tag="LSX49_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HBL7169657.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(10003..10581)
                     /gene="lpcA"
                     /locus_tag="LSX49_003282"
     CDS             complement(10003..10581)
                     /gene="lpcA"
                     /locus_tag="LSX49_003282"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HBL7169658.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            10821..13265
                     /gene="fadE"
                     /locus_tag="LSX49_003283"
     CDS             10821..13265
                     /gene="fadE"
                     /locus_tag="LSX49_003283"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HBL7169659.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALTKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            complement(13308..13754)
                     /gene="ivy"
                     /locus_tag="LSX49_003284"
     CDS             complement(13308..13754)
                     /gene="ivy"
                     /locus_tag="LSX49_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ivy family C-type lysozyme inhibitor"
                     /protein_id="HBL7169660.1"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            13935..14705
                     /gene="yafV"
                     /locus_tag="LSX49_003285"
     CDS             13935..14705
                     /gene="yafV"
                     /locus_tag="LSX49_003285"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HBL7169661.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESDSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNERVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAI
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMMALREYREKFPAWQDADEFTFR"
     gene            complement(14804..14880)
                     /locus_tag="LSX49_003286"
     tRNA            complement(14804..14880)
                     /locus_tag="LSX49_003286"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14844..14846),aa:Asp,seq:gtc)
     gene            complement(15013..15744)
                     /gene="dnaQ"
                     /locus_tag="LSX49_003287"
     CDS             complement(15013..15744)
                     /gene="dnaQ"
                     /locus_tag="LSX49_003287"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HBL7169662.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGETTIQRIVRQASKLRVVFAT
                     DEELAAHEARLDLVQKKGGTCLWRA"
     gene            15809..16276
                     /gene="rnhA"
                     /locus_tag="LSX49_003288"
     CDS             15809..16276
                     /gene="rnhA"
                     /locus_tag="LSX49_003288"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HBL7169663.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCKVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            complement(16273..16995)
                     /locus_tag="LSX49_003289"
     CDS             complement(16273..16995)
                     /locus_tag="LSX49_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414749.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL7169664.1"
                     /translation="MKPARVPQTVVAPDCWGDLPWGELYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     gene            17029..17784
                     /gene="gloB"
                     /locus_tag="LSX49_003290"
     CDS             17029..17784
                     /gene="gloB"
                     /locus_tag="LSX49_003290"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HBL7169665.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAISANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTPSQMYQSLRKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     gene            17856..19214
                     /gene="mltD"
                     /locus_tag="LSX49_003291"
     CDS             17856..19214
                     /gene="mltD"
                     /locus_tag="LSX49_003291"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HBL7169666.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(19263..20033)
                     /locus_tag="LSX49_003292"
     CDS             complement(19263..20033)
                     /locus_tag="LSX49_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL7169667.1"
                     /translation="MTTQSHHDHVEKQFSSQASEYLTSTVHASGQDLQRLAVRLADYP
                     DASVLDMGCGAGHASFVAAQNVSTVVAYDLSAHMLDVVAQAAEARQLKNITTRQGYVE
                     SLPFADNAFDIVISRYSAHHWHDVGAALREVNRVLKPGGLLIVMDVMSPGHPVRDIWL
                     QTVEALRDTSHIRNHASGEWLTLISEANLIVDNLITDKLPLEFSSWVARMRTPEALVD
                     AIRIYQQSASTEVKTYFALQNDGSFTSDIIMLEAHKAA"
     gene            complement(20111..20911)
                     /locus_tag="LSX49_003293"
     CDS             complement(20111..20911)
                     /locus_tag="LSX49_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL7169668.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            21152..22066
                     /locus_tag="LSX49_003294"
     CDS             21152..22066
                     /locus_tag="LSX49_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7169669.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIACSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELIADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(22063..22866)
                     /gene="dkgB"
                     /locus_tag="LSX49_003295"
     CDS             complement(22063..22866)
                     /gene="dkgB"
                     /locus_tag="LSX49_003295"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HBL7169670.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVKTALELDYRAIDNAQIYDNEAA
                     VGQAIAESGVPRHELHITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHSIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRENLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
BASE COUNT         5582 a         5816 c         6030 g         5598 t
ORIGIN      
        1 taataattta attatttttt caccctatta ataatttgcc cctttcactc cccctctatt
       61 taatacctca ccttatgtca ccgccggatt tgcgtgcaca gaaacgccca taccattaca
      121 gcagagaaag taagccatgc tgaagtacag taaaacgcca ggcatcttta aattagaagg
      181 taatcggctt ggacgcccct accatcgcct gccgaccctg tttacgggga attttgatgt
      241 aattgattcg catcttggca gctactttct caaaaagcat cgcagcaata tcaccctaaa
      301 aaagattggc tgcgaaatgg atattattaa taaaaatgcc gagctgatgg tttcccaggt
      361 cgggcatctg gcgtttgata ttgatcgctc cttgctgtta atgctgctgg gcaattttta
      421 tggtctggag tcgtctcttg aagaagcgaa atcacacaat ggattcccga ccaaaacgga
      481 aacacgttta aaaaaccgcc tcgcgctgga tatctgcacg ctgattttta atctgcaaac
      541 ctccggtatt gcgctgaaat taaaactgga cagcagcacg gtaattaccc actgggcgta
      601 tcaattaacc tttacccttg cgggcgatga agagagcagt tttcgtattt tgctcgacga
      661 cgcccacacc gattttattt tgaatctgat ccgccacagc gagcacagta aaccgcagca
      721 ggtggcgaaa tccgttaata aaccggccct gattaaagaa atcatccgct ccctgccgct
      781 gaccctgaac gtcaaaatcg ccgagctatc gatgaatgtc gcggatctgg cacagattaa
      841 agccggggat attttaccca tatcactggg agaaacgttc ccggtggcga ttgggcaatc
      901 tgaattattt agcgccctga ttgtggaaga caaagacaaa ctgtttttgt cggagctggc
      961 gggaaaaaat gagaacaacc atgagtaagc aagaagatat tttagccggg gattttggcc
     1021 tcaccgatga agttgcgcct gtcgccaaat ccgccgacgc cgaaacgctg gtcacccgcc
     1081 tggaagaccg attttccgac tcgatgacgc tactgaaacg cattccggtg accttaacgc
     1141 tggaagtatc gtcggtggaa atcatgttag ccgacctgct taacatcgac gacgacacgg
     1201 tgattgaact ggataaactc gccggggagc cgctggatat taaagtgaac aatatcctgc
     1261 tgggcaaagc ggaagtggtg gtggtcaacg agaagtacgg cctgcgcgtg ctggaattta
     1321 acacccgcga tatcaacgac ctggcgccat gaaacgccgc actcaactga cgctgggcct
     1381 ggcgctgctg gcgctcgccc cgctggcgct ggcccagggc ggcgatatcg cactgcttaa
     1441 cgtggtcacc cacggcaaca ctcaggagta cagcgtcaaa attcaggtac tgattctgat
     1501 gaccctcgtc ggtttgctgc cgacgatggt gctgatgatg acctgtttca cgcgttttat
     1561 tatcgtgctg tcactgctgc gccaggcgct ggggctgcaa caaacgccgc caaaccgcat
     1621 tctgattggt attgcgctct cactcaccct gctggtaatg cgccccatct ggctcaatat
     1681 ttacgaccac gcggtagtgc cgttcgaaaa cgatcagatt accctgaccg atgcgttaag
     1741 caccgccgcg acgccgctaa aacgctttat gctggcgcag accgacaaaa aagcgatggc
     1801 gcaaatcatg accatcggcg gcgcgaaggg caatgccgcc gaccaggatc tctccatcgt
     1861 ggtgcccgcc tatgtactga gcgagctgaa aaccgccttc cagattggct ttatgattta
     1921 catcccgttt ctggttatcg acctgattgt cgccagcgta ttgatggcga tggggatgat
     1981 gatgctgtcg ccgctgattg tttcgctacc ctttaaactg atgctgtttg tgctgattga
     2041 cggctggtcg ctgaccatcg gcacgctcac caccagcatt cgcgggctgg ggctgggctg
     2101 attatgttga ccgtagacgt cgccgccgac attgtcgcca gcggcattaa agtagtgatt
     2161 ttgctggttt cggtactggt ggtgccaagc ctgctggtcg gcctgctggt gagcgtgttc
     2221 caggcggtga cgcagattaa cgaacagacc ctgagctttt tgccaaggct gattgtcacg
     2281 ctggtggtgc tgggcgtgtg cggcaaatgg atgattatcc agttgcatga tctctgcatt
     2341 cacctgttta cccaggccgc gttgctggtt cattgagatg cgcacaagcg acgttacgca
     2401 actgatggat ctggcgctgg ggctgtggtt tcccttcgtg cgcattatgg cgtttctgcg
     2461 ctatatgccg gtgctggata acagcgccct gaccgcgcgc gtgcggatta ttttgtcgct
     2521 ggcgctggcg atcatcatca cgccgttgat cccccatccc attccccaca atctgctatc
     2581 gctcaacagc ctgatcctga cggtggagca aattttatgg ggcatgttat tcgggctgat
     2641 gtttcagttt ttgtttctgg cgctacaact ggccgggcaa attctctcgt tcaatatggg
     2701 gatgagcatg gcggtgatga acgacccgag cagcggcgca tcgaccaccg tgctggcgga
     2761 gctaatcaac gtctacgcga tcctgctgtt ttttgccatg gacgggcatc tgctgctggt
     2821 aagcgtgttg tacaagggct tcacctactg gccgattggc aacgccctgc atccgcaaac
     2881 cctgcgtacc atcgcgctgg cctttagctg ggtgctggcg tcggcatcgc tgctggcgct
     2941 gccgaccact tttatcatgc tgattgtgca gggctgcttt ggcttgctca accgtattgc
     3001 gccgccgctg aacctttttt ctcttggctt tccgatcaac atgctggcgg ggctggtctg
     3061 ttttgccacc ctgctctaca acctgccgga tcactatctg catctggcga attttgtctt
     3121 acaacaactc gacgcgctga aaggtcacta tggcggatag cagcagcgaa gaaaaaacag
     3181 agaaaccctc ggcgcaaaag ctgcgtaaag cgcgtgaaga ggggcaactg ccgcgctcga
     3241 aggatatggg gctggcggcg agcctgtttg cggcgtttgt ggtgatctcc agcagttttc
     3301 cgtggtatgc cgattttgtg cgcgagagct ttatcagcgt gcatcagtat gcgcaggaga
     3361 ttaataaccc gcaggtgatc ggccagtttc tgcgccatca cctgttaatt ctcggcaagt
     3421 ttatcctcac cttgctgccg atgcctgctg ccgcgctgct ctcttcgctg gtgcccggcg
     3481 gctggctgtt tctgccaaaa aaaatcctcc cggatttcag caaaatcagt ccgttaaaag
     3541 gcattgggcg gctgttttcc agtgaacatc tggcggaaac gggaaagatg acggtgaagt
     3601 ctgtggtggt gctggtgatg ctgtgggtaa gcctgcgcaa taactttgcc gcctttctca
     3661 gcctgcaggc gctgccgttc aaactggcga taaatgacgg tttatcgctc tacgccagcg
     3721 tgatgcgcaa ctttgtcatt ctgtttatct tcttcgcgct tatcgacgtg ccgctggcga
     3781 aagccctgtt caccaaaggg ctgaagatga ccaaacagga gctgaaagaa gagtacaaaa
     3841 atcaggaagg taagccggaa gtgaaggcgc gtgtgcggcg actgcaacgg caactggcga
     3901 tggggcaaat ccgcaaagtg gtgccgaaag ccaacgtggt gatcaccaac ccgacccact
     3961 acgccgtggc gttacagtat gaccagtcgc gcgccgccgc gccgtttgtg gtggcaaaag
     4021 gcaccgatga aatcgccctc tatattcgcc aggtcgccac ggagaatcag gtggaagtgg
     4081 tcgagttccc gcggctggca cgctcggttt actacaccac ccaggtgaac cagcaaattc
     4141 cgtttcagct ttaccgggcc atcgcccacg ttctgaccta cgtcctgcaa atgaaacact
     4201 ggcgcgaggg cgcacagccg cgcccggccc tgaacagaca tatttccatt cccaaagagg
     4261 tgcttaaact ggatggcgaa aacaactaaa tcgttccttg cgctgctgcg cggcggcaat
     4321 ctcggcgtgc cgctggtcat actgtgtatt ctggcgatgg ttattctgcc gctgccgcct
     4381 gcgctgctgg atattctgtt caccttcaac attgtgctgg cggtgatggt actgctggtg
     4441 gcggtgtcgg cgaaacgacc gctggaattc agcctgttcc cgaccatttt gctgatcacc
     4501 accttaatgc gcctgacgct taacgtcgcc tctacgcgcg tggtgctgtt gcacgggcat
     4561 ctcggcgcgg gcgcggcggg taaggtgata gagtcgtttg gtcaggtggt gatcggcggc
     4621 aactttgtcg tcggtttcgt ggtgtttatc atcctgatga tcatcaactt tatcgtcgtc
     4681 accaaagggg ccgagcgtat ttccgaggtt tctgcccgct ttaccctgga cgcgatgccc
     4741 ggcaaacaga tggcaattga cgccgatctt aatgccgggt tgatcaacca ggcacaggcg
     4801 cagacccggc gcaaagatgt tgccagcgag gccgattttt acggcgcgat ggacggggca
     4861 tcgaagtttg tgcgcgggga tgccatcgcc gggatgatga ttctggcgat caacctgatc
     4921 ggcggcgtct gtattgggat cttcaaatac aacctgagcg ccgatgctgc cttccagcaa
     4981 tatgtgttga tgaccatcgg cgacggcctg gtggcgcaga tcccttccct gctgctctcc
     5041 accgcggcgg cgattatcgt cacccgcgtc agcgacaacg gcgatatcgc ccatgacgtg
     5101 cgtaatcagt tgctggcaag cccgtcggtt ctctacaccg ccactggaat tatgttcgtg
     5161 ctggcggtgg tgccgggaat gccgcatttc ccgttcctga tgttcagcgc cctgcttggt
     5221 tttaccggct ggcggatgag caagcgcccg caagcggcgg aggcggaaga gaaaagcctc
     5281 gaaacgctaa cccgtacgat gacagaaacc agcgagcaac aggtcagttg ggaaactatt
     5341 ccgctgatcg aacctatcag tttaagcctc ggctacaaac tggtggcgct ggtggataaa
     5401 gcgcagggta atccgctcac ccagcggatt cgcggtgtac ggcaggtgat atccgacggt
     5461 aacggagttc tgctgccgga gatccgtatt cgggaaaact tccgcctcaa gcccagccag
     5521 tacgccattt tcatcaacgg cattaaggct gatgaagcgg atattccggc ggataaactg
     5581 atggccctgc cctccagcga aacctacggc gagattgacg gcgtactggg gaatgacccg
     5641 gcgtacggga tgccggtcac ctggattcaa cccgcgcaga aagcgaaggc gctgaatatg
     5701 gggtatcagg tgatcgacag cgccagcgtg attgccaccc atgtgaataa gattgtgcgc
     5761 agctatattc ctgacctctt taactatgac gatattacgc agctgcataa ccgtttgtcg
     5821 tcgatggcac cgcgactggc ggaagatttg agcgcggcac tcaattacag ccagttgctg
     5881 aaagtgtacc gggcgctact gactgaaggc gtttccctgc gcgatatcgt caccatcgcc
     5941 accgtgctgg tcgccagtag tgcggtgacc aaagatcata ttctgctggc ggcagatgtg
     6001 cgcctggcgc tgcggcgcag cattacccat ccgttcgttc gcaagcagga gctgacggtg
     6061 tatacgctga ataatgagct ggaaaatctg ctgaccaacg tggtgaatca ggcgcaacag
     6121 ggcgggaaag tgatgcttga tagcgtgcca gtggacccga atatgctcaa ccagttccag
     6181 agcacgatgc ctcaggtgaa ggagcagatg aaagcggcgg ggaaagatcc ggtgctgctg
     6241 gtgccgccgc aactgcgccc cttgctggcg cgctacgcaa ggttgtttgc gccggggctg
     6301 catgtgctgt cgtataacga agtgccggat gagctggagt tgaagataat gggggcgttg
     6361 atgtaggcat ccggcatcgg tgcatattgc cggatgcggc gtgaacgcct tatccggcct
     6421 acgggtgagc acggttttgt cggcatgata agacgcgtag cggcgcatct ggcaccggtg
     6481 cacaactgcc ggatgcggcg tgaacgcctt atccggccta cgggtgagcg cggttttgtc
     6541 ggcatgataa gacgcatctg cgtcgcatca ggcatcggcg cacagctata aaatgatacg
     6601 ctccccagca ctaaaatccg ttacgtcctc cgcccaatcg atgggatata accctcgcgc
     6661 gacatcgcga tgaaacgttg agaatggcca atcactcact tgctttaccc aaccatgttt
     6721 tactggattt atataaatat aatcaacatg atggcgatag tcttgggtat tgcgaatggc
     6781 atgctcccaa aaacgcggtt gccagatatt tttcaatcca caagcatggg taaattgctt
     6841 tttaatttcc cgccagcgcg aggaaaaatc atcatcgcct tcaggtaatg tccatatgca
     6901 atgcatatgc tccggcaaaa ctacccaagc gttaatttca aaaggtctgt ctcgcttaac
     6961 gttaataata gcgttacgga gcgtctgaaa ctgggtggtc aaaagttggt ttcgacgatt
     7021 ctgtaaattt accgtgaaaa accaggttcc ccccttgatg taataacgac gatattcaga
     7081 cataacgact cctttttctc aacggtaaga agaaaaggaa aagtcggcaa tgatgttgtg
     7141 ttaaatcggg aaagcggctc gcaaaaaatg cacagattta taggcatgat aagacgcgta
     7201 gcgtcgcatc aggcaccggt acacaaccgc cggatgcggc gtgaacgcct tatccggcct
     7261 acaaaatcgt ctcttccgtc aaaatccgcc gcgcgcccaa aaaatgatcc tgccagaaag
     7321 gttcagctaa ccgacttacc cgaatggttt ccccggtgcg cggtgactcg ataaactgac
     7381 cgtctccaag atatacgccc atatggtcgg ctatctcacg gctgtggata tggaaaaaca
     7441 gcaaatctcc ccggcgcagg tcgttattcg ccacaatcgt tgcccgacgg tagtggtaca
     7501 tctcattggc cgtgcgcggg agcttagcct caaggatctt gttgtaggca taaaaaacca
     7561 acccgctaca gtcgaaacct ttatcaggcc gcgtgccccc ccagacataa ggcttgccaa
     7621 gttgctgttc caggcggtga atcgccactt cggtgatgtt atgcaggtgg ttgctgctga
     7681 ggaaatgatt gttttccgcc agcgcctgcc agcgtctgtc gttcgccttg agcggcgcag
     7741 gaaaccattc tggatgctgt tttatctgct cccgattatg ctggcgcagc gcccttctgc
     7801 ttttagcatt gccttccaca atatagctgg cctgcttttt cagatgggtt tggtactgtt
     7861 ttaataaacg cgcacggttt tgcatccgct ggcgggcggc gtagctaaaa gagatatgtg
     7921 atgtggtggc gctggcgagt aaagggagca aaacgcataa cgaaaacacg cctggatgca
     7981 gaaatctgcc gtgcaagaac gaagacatga aggacataaa ccagctgaat gaaggtgaga
     8041 attttaaaag accggaggag taaacgggat tattaattgc ttatttgcat attactattg
     8101 cggtttcata atcttaggaa ataagaaata aatctacaat ccatgcgctt ttcggactct
     8161 tgaaaactgc acctgtgcta aatttgtaaa ccctgcgccg acaggcttgc gtaaaactct
     8221 tttggtgata atgtgagcct tccaaatcca gactattccg atttgggatt cattttgccg
     8281 tcctggcgtg tgtaaccgtt ttatcaagga ataagcagta tgcgtaaaat cgcattaatt
     8341 cttgcgatgt tgttgatccc atgcgtttcg tttgccggtt tgctgggcag cagtagctcg
     8401 accacgccag tgagcaaaga gtataagcag cagttgatgg gatcccctgt ctacatccag
     8461 atcttcaagg aagaacgtac gctcgatctc tacgtcaaaa tgggcgagca atatcaactg
     8521 ctcgacagct ataaaatctg taaatattcc ggcggcttag ggccaaaaca gcgtcagggc
     8581 gatttcaaaa gcccggaagg gttttatagc gtccagcgta atcagttaaa accagacagc
     8641 cgttactaca aagcgattaa tattggattc ccaaacgcct atgaccgtgc gcatggttat
     8701 gaagggaaat acctgatgat tcacggcgat tgtgtttcca tcggctgcta cgcgatgacc
     8761 aatcagggta ttgatgagat cttccagttc gttactggtg cgctggtgtt tggtcagccg
     8821 agcgtgcaag tgagtattta tccgttccgc atgaccgacg ccaatatgaa gcgccataaa
     8881 tattccaact ttaaggactt ctgggagcaa ctgaagccgg gctacgacta ctttgagcaa
     8941 acccgtaagc caccgaccgt ttctgtggtc aatggccgtt acgtggtcag caagccgtta
     9001 agccacgaag ttgtgcagcc acaactggca tcaaactaca cgctccccga ggcaaaataa
     9061 gcgccattca cctggcataa tcttttgcca ggtttcattg cccgtcagcg gctgtgtcgc
     9121 aatcaccgtg accacatcat tcggtgtggt ctgcgagctg aagtcgattt ccacatcctg
     9181 atccagcaac gttgccacgc caaacggcgc gcggcgggtg atccagtgta aattagtcga
     9241 gcaatacgcc attacatagc gcccgtcaga aagcagcatg ttgaaaacgc ccttctgccg
     9301 cagttcatcc gccagtgagg cgatatattt aaacactgcc gccatgttgc ccggtgtgcg
     9361 cgggtaacgc tgcgttaatt tatgcaggag ccagcaaaag gctttttcgc tatcggtttc
     9421 accgaccggg cggaagttgc cggtttccag tgatttgtag cccgtcagtt gtccattatg
     9481 ggcataagtc cagttacgcc cccataactc gcgggtaaac gggtgagtat tttccagcgc
     9541 cacctcgccc cgattagcct ggcgaatatg agccaccacc gaacaggatt ttatcgggta
     9601 gtcctggaca agtttggcga tgggggaatt aaagctgggt tgcggatctt taaatgtgcg
     9661 acagccttta ccttcgtaaa aggtaatgcc ccagccatct ttatgtggcc cggttccacc
     9721 accacgctgt acaagtccgg tgaaactaaa gcagatatcg gtagggacgt tggcactcat
     9781 cccgagcaat tcgcacatgg gtaacctcca caacagcggg agcgcatggc ccccggcgaa
     9841 gattgattta agaattttca ggtcggatgt ggcgtgaacg cattattcgg cctacggttc
     9901 gggtgcagat tgtaggcatg ataagacgcg tcagcgtcgc atcaggcatc agagcacaaa
     9961 tgccggatgc ggcgtaaacg ccttatccgg cctacgccag acttacttaa ccatctcttt
    10021 ttcaattaac tggatcagga tatggatcac tttaatgtgg atctcctgaa tgcggtcggc
    10081 ataaccaaag tgcggtacgc gaatttcgat atccgccgtg ccagccattt tgccgccgtc
    10141 tttaccggtc agggtgatca ctttcatccc cttctcacgc gccgccgcga tcgctttgat
    10201 cacgtttgca gagttaccgg aggtggagat ccccagcagt acatcgcctt cgcgacctac
    10261 cgcttcaacg taacgggaga aaatatcatt gaaaccaaaa tcgttaccga cgcaggaaat
    10321 atgactaacg tcagaaatgg caatcgccgg gtagcccgga cggttttcac ggtagcgacc
    10381 ggtcaactct tcggcaaagt gcatggcgtc gcaatgggag ccgccgttgc cacaggaaag
    10441 cactttgcca ccggctttaa agctgtctgc taacaggacc gccgcgcgct gaatggcgtg
    10501 aatattggcg tcatctttta aaaagttagc cagcgtttcc gccgcttcgt tcagttcatt
    10561 acgaataaga tcctggtaca tgaggatatc cttcagcata aatgtaatag acaaaatgca
    10621 gtgtaccgga taccgccaaa agcgagaagt acgggcaggt gctatgacca ggactttttg
    10681 acctgaagtg cggataaaaa cagcaacaat gtgagctttg ttgtaattat attgtaaacg
    10741 cattgctaaa tgtttttaca tccactacaa ccatatcatc acaagtggtc agacctccta
    10801 caagtaaggg gcttttcgtt atgatgattt tgagtattct cgctacggtt gtcctgctcg
    10861 gcgcgttgtt ctatcaccgc gtgagcttat ttatcagcag tctgattttg ctcgcctgga
    10921 cagccgccct cggcgttgcg ggtctgtggt cggcgtgggt actagtgcct ctggccatta
    10981 tcctcgtgcc atttaacttt gcgcctatgc gtaagtcgat gatttccgca ccggtatttc
    11041 gcggtttccg taaggtgatg ccgccgatgt cgcgcactga gaaagaagcg attgatgcgg
    11101 gcaccacctg gtgggagggc gacttgttcc agggcaagcc ggactggaaa aagctgcata
    11161 actatccgca gccgcgcctg accgctgaag agcaagcgtt tctcgacggt ccggtagaag
    11221 aagcctgccg gatggcgaat gatttccaga ttactcatga gctggcggac ctgccgccgg
    11281 agttgtgggc gtaccttaaa gagcatcgtt tcttcgcgat gatcatcaaa aaagagtacg
    11341 gcgggctgga gttctcggct tatgcccagt ctcgtgtgct gcaaaaactc tccggcgtga
    11401 gcgggatcct ggcaattacc gtcggcgtgc cgaactcatt aggcccgggc gagctgctgc
    11461 aacattacgg cactgacgag cagaaaaatc actatctgcc gcgtctggcg cgtggtcagg
    11521 agatcccttg ctttgcactg accagccccg aagcgggttc cgatgcgggc gcgattccgg
    11581 ataccgggat tgtctgcatg ggcgaatggc agggccagca ggtgctgggg atgcgtctga
    11641 cctggaacaa acgctacatt acgctggcac cgattgcgac cgtgctgggt ctggcgttta
    11701 aactctccga cccggagaaa ttactcggcg gtgcagaaga tttaggtatt acctgtgcgc
    11761 tgatcccgac caccacgccg ggcgtggaaa ttggtcgtcg ccacttcccg ctgaacgtac
    11821 cgttccagaa cggaccgacg cgcggtaaag atgtgttcgt gccgatcgat tacatcatcg
    11881 gcgggccgaa aatggccggg caaggctggc ggatgctggt ggagtgcctc tcggtaggcc
    11941 gcggcatcac cctgccttcc aactcaaccg gcggcgtgaa atcggtagcg ctggcaacgg
    12001 gtgcgtatgc gcacattcgc cgtcagttca aaatttctat tggtaagatg gaagggattg
    12061 aagagccgct ggcgcgtatt gccgggaacg cctacgtgat ggatgctgcg gcatcgctga
    12121 ttacctacgg cattatgctc ggtgaaaaac ccgccgtgct gtcggctatc gttaagtatc
    12181 actgtaccca ccgcgggcag caatcgatta tcgacgcaat ggatatcacc gggggtaaag
    12241 gcattatgct cgggcagagc aacttcctgg cccgtgctta ccagggggca ccgattgcca
    12301 tcaccgttga aggggcaaat attctgaccc gtagcatgat gatcttcggt cagggggcga
    12361 ttcgttgcca tccgtacgtg ctggaagaga tggaagcggc gaagaacaat gacgtaaacg
    12421 cgttcgataa actgctgttc aaacatatcg gtcacgtcgg tagcaacaaa gttcgcagct
    12481 tctggctggg cctgacgcgc ggtttaacca gcagcacgcc aaccggcgat gccactaaac
    12541 gctactatca gcacctgaac cgcctgagcg ccaacctcgc cctgctttct gatgtctcga
    12601 tggcggtgct gggcggcagc ctgaaacgtc gtgagcgcat ctcagcccgt ctgggggata
    12661 ttttaagcca gctttacctc gcctctgccg ttctgaagcg ttatgacgac gaaggccgta
    12721 atgaagccga cctgccgctg gtgcactggg gcgtacagga tgcgctgtat caggcagaac
    12781 aggcgatgga cgatttactg caaaacttcc cgaaccgcgt ggttgccggg ctgctgaatg
    12841 tggtgatctt cccgaccgga cgtcattatc tggcaccgtc tgacaagctg gatcataagg
    12901 tggcgaagat tttacaagtg ccgaatgcca cccgttcacg tattggtcgc ggtcagtacc
    12961 tgactccaag cgagcataac ccggttggtt tactggaaga ggcgttggtg gatgtgattg
    13021 ccgccgaccc gattcatcag cggatctgta aagagctggg taaaaatctg ccatttaccc
    13081 gtctggatga actggcgcac aacgcgctga cgaaggggct gattgataaa gatgaagccg
    13141 ctattctggt gaaagctgaa gaaagccgtc tgcgtagtat taacgttgat gactttgatc
    13201 cagaagagct ggcgacgaag ccggtaaagt tgccggagaa agtgcggaaa gttgaagccg
    13261 cgtaattgaa taacggagcc gaaaggctcc gtttttttat cggctaatta tttaaaatta
    13321 aagccatccg gatggttttc caggctgccg gtcaacgccg cgaacagcac cgttttgcca
    13381 tcaatcgaaa gcgcatcatt cacattcagc caggtgagtt tctcttgcga cgttttctca
    13441 tcaatagtcg agaacagccc cgtcatctga ttagatttct cggaccacat cacagcgata
    13501 cgttgcgagc cacagtcatg aggtttgcac gcgctcatca cctgatacgt ctcatctccc
    13561 aatgtcacgg tttgtgcggg agtataagta ccgcctttca tcacccaggc aggcagctta
    13621 tgcccttgca ccatctgatt aaacgccgct ttggtggttt cgccctttgc aagactgcta
    13681 atggttaaat catcctgcgc cattgcactg gtggcgatga ccagagcggc gactgtcgtt
    13741 attgccttaa acatcattcc tcccgggctt atcctgccca tgtgattaac tccctaaagc
    13801 ctggcgataa cacgataatt tgcaaatcag atatttccaa tatcagcatt tgttatcaat
    13861 ttattctgcg ctaaggcaac tgcctgataa ggtgttagag ttataaaacc cttcgcataa
    13921 aggagttgta caccgtgcct ggtttgaaga ttacgctttt gcagcaacca ctggtgtgga
    13981 tggatggtcc tgccaacctg cgccattttg atcgtcaact ggaaggtatt accgggcgcg
    14041 atgtgatcgt tctaccggag atgtttacca gcggctttgc catggaagcg gcagcttcgt
    14101 cgctagcaca agatgacgta gtgaactgga tgaccgctaa agcgcagcag tgcaatgcgc
    14161 tgattgcagg cagtgttgca ttacaaacgg agtctgattc ggttaaccgc tttttgctgg
    14221 ttgagccggg cggcacggta catttttatg ataagcgtca tctgttccgc atggcagatg
    14281 agcatctgca ttataaagca ggcaatgagc gagtgattgt ggaatggcgc ggctggcgta
    14341 ttttaccgct ggtgtgctac gacttacgtt ttccggtgtg gtcgcgcaat ctcaacgatt
    14401 atgacctcgc catctacgtt gccaactggc ctgcaccgcg ctctctgcac tggcaggcat
    14461 tactgacagc ccgcgcgatt gagaatcagg cgtatgtagc gggatgtaat cgcgtcggca
    14521 gcgatggcaa cggctgccat tatcgcggtg acagccgggt gattaatcca caaggcgaga
    14581 ttatcgctac tgccgacgcg catcaggcaa cgcgcattga tgcggagcta tcgatgatgg
    14641 cattgcggga atatagagaa aagtttccgg catggcagga tgcggatgag ttcacatttc
    14701 gttagagggt gaatatggct acgagataag tttcgtggct atttttctct ggaacttaaa
    14761 cgacgaaatc ccgaatcagt aatgattcgg gctttctgaa tattggcgga acggacggga
    14821 ctcgaacccg cgaccccctg cgtgacaggc aggtattcta accgactgaa ctaccgctcc
    14881 gcgttgtgtt ccgttgggaa cgaggcgaat attacggatt gcctcaccct tcgtcaacgg
    14941 tttttctcat cttttgaatc gtttgctgca aaaatcgccc aagtcgctat ttttagcgcc
    15001 ttttacaggt atttatgccc gccagaggca ggttccgccc ttcttctgca ccagatcaag
    15061 acgggcttca tgtgctgcaa gctcttcatc tgtcgcaaaa acaacgcgta acttacttgc
    15121 ctgacgcaca atgcgctgaa ttgttgtttc accttgttgc tgttgtgtct ctccttccat
    15181 cgcaaaagcc atcgacgttt gaccaccggt catcgccaga taaacttccg caaggatctg
    15241 ggcatcgagt aatgccccat gcagcgttcg tttactgtta tctatttcgt agcgggcaca
    15301 taacgcatcg aggctgttgc gtttaccggg aaacattttc ctcgccaccg caaggctatc
    15361 ggtgacctta cagaaggtat tggtcttcgg aatatcgcgc ttaagcaacg aaaactcgta
    15421 gtccataaag ccgatatcaa acgctgcgtt atggatcacc aactccgcgc cgcggatata
    15481 gtccatgaac tcatcggcta cctcggcaaa cgtgggctta tcgagcaaaa attcatcggc
    15541 aataccatgt acgccaaagg cttccggatc caccagccga tcgggtttga gataaacatg
    15601 gaagttattg cccgtcaggc gacggttcac cacttcaacg gcaccaatct caatgatctt
    15661 gtggccttca tagtgcgcac caatctggtt cataccggtg gtttcagtat cgagaacgat
    15721 ctggcgtgta attgcagtgc tcatagcggt catttatgtc agacttgtcg ttttacagtt
    15781 cgattcaatt acaggaagtc taccagagat gcttaaacag gtagaaattt tcaccgatgg
    15841 ttcgtgtctg ggtaatcctg gacctggggg ttacggcgct attttacgct atcgcggacg
    15901 cgagaaaacc tttagcgctg gctacacccg caccaccaac aaccgtatgg agttgatggc
    15961 cgctattgtc gcgctggagg cgttaaaaga acattgcaaa gtcattttga gtaccgacag
    16021 ccagtatgtc cgccagggta tcacccagtg gatccataac tggaaaaaac gtggctggaa
    16081 aacagcagac aaaaaaccag taaaaaatgt cgatctctgg caacgtcttg atgctgctct
    16141 ggggcagcat caaatcaaat gggaatgggt taaaggccat gccggacacc cggaaaacga
    16201 acgctgtgat gaactggctc gtgctgcggc aatgaatccc acactggaag atacaggcta
    16261 tcaagtcgaa gtttaagcct gtggtttacg acattgccgg gtggcaccaa ccgcctggcg
    16321 aattcgcggt ttattcttgc tctgtttcat cggatttagc gttaaaggaa tagtccgttt
    16381 ccgggcaaca ataagttgta agcaaccaag cgcaggaata tgcgcattca atagttttcc
    16441 tccgtgtttg ttccacggga gaacgtggaa acggctggcg tgtagcactt caaaattcaa
    16501 caaagagagc cagtccagct gccgcatcag agtaaacatc cggctgttat agggcgatgt
    16561 tttgcgcaat accggcacaa gtttgcgtaa tcccattaaa ctgatgggat tgaagccact
    16621 aatcaccagc caaccatcat caatcagtac ccgatcggct tcacgcaata aacgatgcgg
    16681 atcagtgcac cacggcaatg tatgtgccag tagacaaaca tcaacggatt tatcggcaaa
    16741 aggaagatga agtgggtccg cctgcacctg gacgggcatt ccttgcgcag aaacattcac
    16801 ttgatgagaa accgcgcacg cttcgcaatt gatttctgcg cttaaattgc caatcttaag
    16861 cagatgaaaa ccatacattt tagtgaacca cgggttgagc tgacgctcca gcgccttgcg
    16921 ataaagctct ccccagggca aatcgcccca gcaatcagga gccacgacag tttgagggac
    16981 tcttgccggt ttcatcacaa ccttccgttt cacactgaga ggtaatctat gaatcttaac
    17041 agtattcccg cctttgatga caattacatc tgggttttga atgatgaagc aggtcgctgt
    17101 ctgattgtcg atcccgggga cgcagagcca gtattaaacg ccatttccgc caataactgg
    17161 caaccggagg ccatatttct cacccaccat caccacgatc acgttggcgg cgtaaaagaa
    17221 ctggtggaaa agtttccgca aattgtggtg tatggaccac aagagacaca agataaggga
    17281 acaacacagg tagtcaaaga tggcgaaact gccttcgttt tggggcatga atttagtgta
    17341 attgccacac cgggtcacac tttaggacat atctgttact tcagtaaacc ttatctattt
    17401 tgcggcgaca cgctgttttc tggtgggtgt ggtcggttgt ttgaagggac accatcacaa
    17461 atgtatcaat cacttagaaa gttaagtgcg ttacctgacg acacattggt atgttgtgct
    17521 catgaatata ccttatcaaa tatgaagttt gctttgagta ttcttccgca cgatttgtcc
    17581 ataaatgatt attatcgtaa agttaaggag ttacgggcaa aaaatcaaat aacactaccc
    17641 gtaattctga aaaatgagcg gcaaattaat gtttttttaa gaacggaaga tattgattta
    17701 attaatgtaa ttaatgaaga aacattattg caacaacctg aagaacgttt tgcatggtta
    17761 aggtcaaaga aagataggtt ctgataaaac tttcttgtca tcggctccgt tcgccgttat
    17821 gatcggtcgt cttttaagca actattgaca cacacatgaa ggcaaaagcg atattactcg
    17881 cctctgtcct gctcgtgggt tgccagagca ccggcaacgt tcaacagcac gcacagagcc
    17941 tttctgcagc tggtcaaggg gaagcagcaa agtttacaag tcaggcacga tggatggacg
    18001 atgggacgtc tatcgcgcca gatggtgact tgtgggcttt cattggcgac gagctaaaga
    18061 tgggaattcc ggaaaacgac cggattcgcg aacagaaaca gaaatattta cgcaataaga
    18121 gctatctcca cgatgtaact ttacgggcag agccgtatat gtactggata gccgggcaag
    18181 ttaaaaaacg taacatgcct atggaactgg tactactacc catagtggag agcgcttttg
    18241 atcctcacgc aacgtctggc gccaatgccg cgggcatctg gcagatcatt ccgagcacgg
    18301 ggcgcaatta tggtttgaaa cagacccgca attatgacgc gcgtcgcgat gttgttgctt
    18361 caacaactgc cgcgctgaac atgatgcagc gtctgaacaa gatgtttgac ggcgactggc
    18421 ttctgaccgt agcggcttat aacagcggcg aaggtcgggt catgaaggca attaaaacga
    18481 acaaagcgcg tgggaaatcc acggacttct ggtcgttacc gttgccgcag gaaacgaagc
    18541 agtacgtgcc taaaatgctg gcattgagtg atattctcaa aaacagcaag cgttatggcg
    18601 tacgtctgcc aacgaccgat gaaagccgtg ctctggcacg tgtgcacctg agcagcccgg
    18661 ttgaaatggc gaaggttgca gatatggcgg ggatttccgt cagcaagctg aagacattca
    18721 acgcaggcgt gaaaggctcc acgctgggcg caagtggtcc gcagtacgtg atggtgccaa
    18781 agaagcatgc agatcaactg cgtgaatctc tggcttcagg cgaaattgct gctgtacagt
    18841 cgacgctggt tgccgacaat acgccactta acagccgtgt ttacaccgta cgctctggcg
    18901 acacgctttc aagtatcgct tcacgtctcg gcgtaagcac caaagatttg cagcagtgga
    18961 acaaactgcg cggatctaag ctgaagccag gccaaagttt gacgattggt gcaggcagta
    19021 gcgcacagcg actggcaaac aacagcgata gcattacgta tcgtgtgcgc aaaggcgatt
    19081 cgctttcaag cattgctaaa cgccacggcg tgaacatcaa agatgtaatg cgctggaaca
    19141 gcgacactgc gaatctgcaa ccaggcgata agctgacgtt gtttgtgaaa aacaacaaca
    19201 tgccagattc ctgacaaacc agataataaa aaaggcaccg attcccccgg tgcctttttt
    19261 atttatgccg ctttatgtgc ttctagcatg atgatatcac tggtgaaaga gccatcattc
    19321 tgcaaggcaa aatacgtttt cacctctgtc gatgcgctct gttggtaaat gcgaatagcg
    19381 tctactaacg cttctggcgt acgcattctc gctacccatg aagaaaattc cagcggtaac
    19441 ttatctgtaa ttaaattatc aactatcaga ttggcttcac tgattaacgt caaccactca
    19501 ccgctggcgt ggttccgtat gtgagatgta tcgcgtaatg cttctaccgt ctgtaaccag
    19561 atgtcgcgca ctgggtgacc cggagacatt acgtccatca caatcagcag accaccgggt
    19621 ttcaataccc ggttcacttc acgcaatgct gcaccaacat catgccaatg atgggcagaa
    19681 taacggctga taacaatatc aaatgcgtta tcggcaaatg gcaggctttc gacataaccc
    19741 tggcgggtgg tgatattttt cagttgccgg gcttcggcag cttgtgccac gacatccagc
    19801 atatgggcag ataagtcata cgccaccacc gtgctcacgt tttgcgcagc gacaaagctg
    19861 gcatgccctg ctccgcagcc catatcaagt acacttgcat caggataatc agccagacgc
    19921 accgccagac gctgtaaatc ttgtccggat gcatgtacgg tactggtcag atattcgctg
    19981 gcttgagagc taaactgctt ttctacgtgg tcatggtggg attgtgttgt cattgcgctg
    20041 tccttttgtt atttgagtat aaaagggcag cgccaaacgt tggtctgccc tgtggcagac
    20101 ctgacatacc ttatttatca ggcttgccgg gactgaattc aacgagtagc ggattgtgat
    20161 cggacgcgcg cgtaaccagt acagaagctt cgctgacgtt cagaccacgg tagaaaacaa
    20221 aatcgagcgg gcgaccaaac gcccgacggc gctgatcatc ggtaaaacgc acctggcgca
    20281 gcgacatttc ccgcgcaaag cgatataacg cgttcatcct tctacggctc caggcattga
    20341 aatctcccgc cataatgacc gggccactgt ggtgagctat ctgatcgcca ataggaagta
    20401 actgcttact atagacatcc acgcccagac tgaagttgac ggcgtgtata ttaaccacca
    20461 tcaacaggcg ggtgtcaggt aacggataga ccgtcaccag tgccgacttc gccagacgca
    20521 aaatgggttc tcgttcacgt aacgggcagc aatacactgg atgtgccgcc gaaagggtca
    20581 ttacgccaga aggatgttgt ggcagcacga aagcgggtac ctgatcggcg gcaagatagt
    20641 tagcagtcgc aaactgtact aactctggcg ttgtctgcgc ttcctgcaat aacaccagat
    20701 gtgcatcttt gccgtagttc tttaataccg acaaccattc agcgcgttgc tgtttgtata
    20761 tgttccacac caggatccga atacgctctt cggtacttaa cggttctcca ggtggtaatg
    20821 cctggccgat gctcgcaaaa gaccccggcg gtaagatcct ttccgcaggt tgtccggcaa
    20881 catagcgcat ggcataggtg ttttttcgca cttttgactt tgaaacctct atcacgtcaa
    20941 cccttccgca ctcgggaggg ttctactgtt atagggattt tagctcactc tttcaacgag
    21001 caattgtata ttgttatgta agcaagtgct tacaccggtc aggattttgc tcattattga
    21061 gaacattaaa tcggatggca tatctcgcat cctgatggtt taatgacaaa taaattcaaa
    21121 atatctcttc tattttgcaa caggagcaaa aatgaaagcc acgtcggaag aactcgccat
    21181 ttttgtttca gtcgtcgaaa gcggcagctt tagccgggca gcggaacaat tagggcaagc
    21241 aaactcagcg gtaagccggg cggtgaaaaa gctggagatg aaacttggcg ttagcctgct
    21301 taatcggacc acgcggcaac ttagcctgac ggaagaaggc gagcgttatt ttcgtcgcgt
    21361 acagtcaatt ttgcaggaga tggcagcggc agaatcagaa attatggaga cgcgtaatac
    21421 accgcgtgga ctgttacgga tcgatgccgc aactccagtg gtgctgcact ttctgatgcc
    21481 gttgattaag ccttttcgtg aacgctatcc ggaagtcact ttatcgctag tctcctccga
    21541 aacgattatt aatttgatcg aaagaaaagt ggatgtcgcg atacgcgccg gtacgttaac
    21601 ggattccagc ttacgtgcca ggccgctatt taacagttat cgaaaaatta tcgcctcccc
    21661 cgattatatt tcccgctacg ggaagccaga aacgatcgac gatttaaagc aacatatttg
    21721 cctgggattc actgaacccg cttccctcaa tacctggccg atagcctgta gcgatggaca
    21781 attacatgag gttaagtacg gtttgtcatc caatagtggg gaaacactga aacagctttg
    21841 cctgagtggc aacgggattg cgtgtttgtc cgactacatg atcgacaaag aaatcgctcg
    21901 cggagaattg gtggagttaa tagcagataa agtgttgcca gtagaaatgc cattcagtgc
    21961 agtctattac agcgaccgtg cggtaagtac gcgcatccgg gcttttatcg atttccttag
    22021 cgagcatgta aaaacagctc ccggaggagc tgtcagagag gcttaatccc attcaggagc
    22081 cagaccttcc gggctaacca ggcggtcgtt gcaatccagt gcggcgatcg cttttttatc
    22141 ttcggcatca agctgtaaat tttgtgcctt aagattactc tccaggtttt cacgtttagt
    22201 agaagaagga attactgagt aaccttcccc catagcccac gccagaatca cttgagccgg
    22261 agtcgcattg tgtttagctg caatacgagc aataacctca tctttcagtg ccttgccata
    22321 cgccagcgtc atataggaag taatatggat actgtgctgt ttagcccaag cgaccacttt
    22381 acggttttgc agataaggag agagttcaat ctggttagta gcgatgtttt cagcgccaac
    22441 agcagcaatc gctttttcca tcaatgggat cgtaaagttg gaaataccga tctcacgcgt
    22501 cagcccttgt tttttggctt ccagcagcgc ctgcataaac tcttcaacag agacttcatc
    22561 gtttggtgac ggccagtgga ttagcgtcag atcaacataa tcggtacgca atttttgcag
    22621 gctctctttc agactcggga tcaatttgtc tttgctgaga ttttcaatcc agattttagt
    22681 ggtgatgtgg agttcatgac gtggcacgcc actttctgca atcgcctgac ctactgcggc
    22741 ttcgttatca tagatttgtg cgttatcaat tgcgcgataa tcaagttcaa gcgccgtttt
    22801 cacagatgaa ataacaacgt cgtctttcag acggaaagtg cctaaaccaa atgcagggat
    22861 agccataata tgcctctttt aatgctattt tcgttaactg aggtgattat gggcttcaga
    22921 ctgttgcgga aaaatggcgt aaaacgcaga ggatttttgc gattttggca ataatagaaa
    22981 tacaaacgaa aaaaaacctc gagcgttaac tcgaggcttc ttagta
//
LOCUS       DAFGPF010000076        22972 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFGPF010000076 DAFGPF010000000
VERSION     DAFGPF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22972
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.076"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            56..1309
                     /locus_tag="LSX49_003296"
     CDS             56..1309
                     /locus_tag="LSX49_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169671.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNHFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTARYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHHRLHA"
     gene            1706..2041
                     /locus_tag="LSX49_003297"
     CDS             1706..2041
                     /locus_tag="LSX49_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HBL7169672.1"
                     /translation="MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETATTPAPTATTT
                     KAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQP
                     AKPAAQPAA"
     gene            2134..2217
                     /locus_tag="LSX49_003298"
     CDS             2134..2217
                     /locus_tag="LSX49_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169673.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            2317..3138
                     /locus_tag="LSX49_003299"
     CDS             2317..3138
                     /locus_tag="LSX49_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HBL7169674.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVAKSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(3177..3506)
                     /gene="mdtI"
                     /locus_tag="LSX49_003300"
     CDS             complement(3177..3506)
                     /gene="mdtI"
                     /locus_tag="LSX49_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HBL7169675.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(3493..3858)
                     /gene="mdtJ"
                     /locus_tag="LSX49_003301"
     CDS             complement(3493..3858)
                     /gene="mdtJ"
                     /locus_tag="LSX49_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HBL7169676.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            4270..5304
                     /gene="tqsA"
                     /locus_tag="LSX49_003302"
     CDS             4270..5304
                     /gene="tqsA"
                     /locus_tag="LSX49_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
                     /protein_id="HBL7169677.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIA
                     VILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIM
                     TPLQAIEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
                     MLLEVPQLPGKFQQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSI
                     AVLLSDLNKE"
     gene            complement(5329..6717)
                     /gene="pntB"
                     /locus_tag="LSX49_003303"
     CDS             complement(5329..6717)
                     /gene="pntB"
                     /locus_tag="LSX49_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HBL7169678.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALIVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(6728..8260)
                     /gene="pntA"
                     /locus_tag="LSX49_003304"
     CDS             complement(6728..8260)
                     /gene="pntA"
                     /locus_tag="LSX49_003304"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HBL7169679.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQTAQKAAPEVKTE
                     EKCACSPWRKYALMALAIILFGWMASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            8784..9728
                     /locus_tag="LSX49_003305"
     CDS             8784..9728
                     /locus_tag="LSX49_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBL7169680.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            9914..11296
                     /locus_tag="LSX49_003306"
     CDS             9914..11296
                     /locus_tag="LSX49_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL7169681.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            11333..12055
                     /gene="folM"
                     /locus_tag="LSX49_003307"
     CDS             11333..12055
                     /gene="folM"
                     /locus_tag="LSX49_003307"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HBL7169682.1"
                     /translation="MGKTQSLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAI
                     DGLIKAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLTDVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSLPLDGGRHLR"
     gene            complement(12052..12387)
                     /locus_tag="LSX49_003308"
     CDS             complement(12052..12387)
                     /locus_tag="LSX49_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HBL7169683.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLASLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            12516..13235
                     /gene="rstA"
                     /locus_tag="LSX49_003309"
     CDS             12516..13235
                     /gene="rstA"
                     /locus_tag="LSX49_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HBL7169684.1"
                     /translation="MNTIVFVEDDAEVGALIAAYLAKHDMQVTVEPRGDRAEETILRE
                     NPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATVTKGIQETSLTPYKALHFGTLTIDPINRVVSLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAA
                     EPYRIKTVRNKGYLFAPHAWE"
     gene            13239..14540
                     /gene="rstB"
                     /locus_tag="LSX49_003310"
     CDS             13239..14540
                     /gene="rstB"
                     /locus_tag="LSX49_003310"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HBL7169685.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLSERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLAQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            14616..15545
                     /gene="tus"
                     /locus_tag="LSX49_003311"
     CDS             14616..15545
                     /gene="tus"
                     /locus_tag="LSX49_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HBL7169686.1"
                     /translation="MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNFSQAALVSHIQHINKLKTTFEHIVTVESELPSVARFEWVHRHFPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(15542..16945)
                     /gene="fumC"
                     /locus_tag="LSX49_003312"
     CDS             complement(15542..16945)
                     /gene="fumC"
                     /locus_tag="LSX49_003312"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HBL7169687.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLSEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DRWVRPEQMVGSMKAGG"
     gene            complement(17088..18734)
                     /gene="fumB"
                     /locus_tag="LSX49_003313"
     CDS             complement(17088..18734)
                     /gene="fumB"
                     /locus_tag="LSX49_003313"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HBL7169688.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILCDPEASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            18933..20108
                     /gene="manA"
                     /locus_tag="LSX49_003314"
     CDS             18933..20108
                     /gene="manA"
                     /locus_tag="LSX49_003314"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HBL7169689.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVHDAAGDIVSLRDVIESDKATLLGDAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     RNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
                     VAGAHPAIAHFLQQPDAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANKLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETT
                     ISQQSAAILFCVEGDATLCKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            20209..21717
                     /locus_tag="LSX49_003315"
     CDS             20209..21717
                     /locus_tag="LSX49_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HBL7169690.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKVNPWIKSGQSVIFNESVDHGPFP
                     LAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATELMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYANGQITLNGQKMPLEDFVGMFAMPTLNVPAVPAIPQQ"
     gene            complement(21762..22972)
                     /gene="uidC"
                     /locus_tag="LSX49_003316"
                     /pseudo
     CDS             complement(21762..22972)
                     /gene="uidC"
                     /locus_tag="LSX49_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416132.2"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glucuronide uptake porin UidC"
BASE COUNT         5656 a         5933 c         5547 g         5836 t
ORIGIN      
        1 ttttcctaat ctattcataa gcctgatcca caggcatatt tagcaaggat ttcaagtgag
       61 ccgtactaca actgttgatg gcgctccggc aagcgacact gacaagcaaa gcatttctca
      121 gccaaatcat tttattaaac gcggtacgcc gcaatttatg cgcgtcaccc tggcgctttt
      181 ctctgccgga ctggcaacct tcgcacttct ctattgtgtg caacctatcc ttccggtgct
      241 ttcgcaggag tttggtttaa cgcctgcgaa cagtagtatt tcactgtcca tttcaacggc
      301 gatgttggct atcggtttgc tgtttactgg cccgctatcc gatgccattg gtcgcaaacc
      361 agtgatggtc acggcgctac tgttggcctc catttgtacg ttactttcga caatgatgac
      421 cagctggcac ggcattttga ttatgcgcgc cttgattggg ctttcgttaa gtggcgtggc
      481 agccgttggc atgacttatc ttagcgagga aatccaccct agtttcgtgg ccttttcaat
      541 ggggttgtat atcagcggca actcaattgg cggcatgagc ggacgcttaa ttagcggtgt
      601 cttcacggac ttttttaact ggcgaattgc tctggcggca atcggttgtt tcgcgctggc
      661 ctcggcgttg atgttctgga aaatcctccc tgaatcacgc cattttcgcc cgacttcgct
      721 gcgccctaag acgttattta tcaactttcg tctgcactgg cgtgaccggg gattaccgtt
      781 attgttcgca gaaggctttt tgctgatggg gtcgttcgtc acgctgttta attacatcgg
      841 ctataggttg atgctttccc cctggcatgt cagtcaggcc gtggttggct tattatcgct
      901 ggcttatttg accggtacat ggagctcacc caaagccgga accatgaccg cccgctatgg
      961 acgcggtccg gtgatgttgt tttcgacggg ggttatgctg tttggtttac tgatgacctt
     1021 attcagctcg ctgtggctga tctttgccgg aatgttactc ttctcagccg gattcttcgc
     1081 agcccactcc gttgccagca gctggatcgg cccccgcgca aaacgcgcta aaggccaggc
     1141 ctcctcgctg tatctgttca gttactatct ggggtcgagt attgccggga cgctgggtgg
     1201 tgttttctgg cataactatg gctggaacgg cgtcggcgca tttattgctc tgatgctggt
     1261 cattgctctg ctggtcggga cgcgtttgca tcatcgtctg cacgcctgaa aaaataagtc
     1321 cggactgagg taaatacccg tccggactta ttgcctgctc aaaccaacgt taatagccat
     1381 cctaaaatag acgaagcgcc agccaattcc cgcagcgcat ctagcgtcat caggattata
     1441 agtacccaaa taaacggatt cattttgctg tgtgtcattt attactgatg cgcagttatt
     1501 ctaccgcttt gtaagtagta aaatagttaa cacgatcaag actactttat tggtagctaa
     1561 attttcctta agtcacaata cgttattatc aatgctgtaa tttattcagc gtttgtacat
     1621 atcgttacac gctgaaacca accactcacg gaagtctgcc attcccaggg atatagttat
     1681 ttcaacggcc ccgcagtggg gttaaatgaa aaaacaaatt gagggtatga caatgaaaaa
     1741 agtattagct ctggttgttg ccgctgctat gggtctgtct tctgctgcct ttgctgcaga
     1801 gactgcgacc acacctgctc cgactgcgac gaccaccaaa gcagcgcctg cgaaaaccac
     1861 acatcataaa aaacagcata aagcagcacc tgcccagaaa gcgcaggcgg ctaaaaagca
     1921 tcataaaaat gccaaagctg aacagaaagc tcctgaacaa aaagcgcagg cagcgaagaa
     1981 acacgccaag aaacacagcc atcagcaacc ggcaaaacct gctgcacaac ccgcagcgta
     2041 agttttcaac agtaatgctg gcgcgccccc tcgcgcctga aaattacggt gctaagcggg
     2101 taacgtttag caccgccttt agcggagggt agtatggtgg gccgttatcg ctttgagttc
     2161 attcttatca tccttatttt atgcgcactg attgccgccc gtttttatct ttcctgatcg
     2221 tagttatctg attttactcc cactttcatc ccgtcccgtc tatagtattt atgagggttt
     2281 gcttttaata atcataatta cccaccagag tgtgatatgc gtacaaccat tgctgtagtg
     2341 ttgggtgcaa ttagtttgac gtctgctttt gtgtttgcag ataaaccaga cgttgccaaa
     2401 tcggcaaacg atgaggtcag caccctgttt tttggtcatg atgatcgtgt gccagtgaat
     2461 gacacgaccc aatcaccgtg ggatgcggtt ggccaactgg aaacggccag cggcaattta
     2521 tgtacggcga cgctgattgc acccaatctg gcattaacgg caggacactg tttattgacg
     2581 ccgccaaagg gtaaagccga taaagcggta gcgctgcgtt tcgtgtcaaa taaaggtctt
     2641 tggcgctatg agatccacga catagaaggc cgcgttgatc caacactggg aaagcggtta
     2701 aaagcagatg gggatggctg gattgtacct cccgcagctg cgccgtggga cttcggtttg
     2761 attgtgctac gtaatccccc ttctggcatt acaccgttgc cgttatttga gggagataaa
     2821 gccgcgctta ccgccgcatt aaaagcggct ggtcgtaaag tgactcaggc gggctaccct
     2881 gaagatcatc tcgatacgtt gtacagtcat caaaactgtg aagtgactgg ctgggcgcaa
     2941 acgtcggtga tgtcgcatca gtgcgatacc ttgccgggtg acagcggttc gcctctgatg
     3001 ttgcataccg atgacggctg gcaattaatt ggggtgcaaa gctcggctcc tgccgcgaaa
     3061 gatcgctggc gcgccgataa ccgggccatt tctgttaccg gttttcgcga caagctggat
     3121 caactgtcgc aaaaataatg ttcaaacgct gcccgacagc gcgggcagcg tgttcatcag
     3181 gcaagtttca ccatgatcat tccagccaac agcagcacca ggccaatcca gcctttacga
     3241 tttaaccgtt gaccaaacaa gatccaacct gcggctaacg tggcggcaat accaaacccg
     3301 ccccacaatg cataagcgac agacaagtcg atccctttaa cggcctgaga aagcgcacta
     3361 aaggcagcca gcaccgccgc cagagagagc aagccaaata ttttgcgacg aaagccgtca
     3421 gaaaatttca aaaagacgtt agcaacgatt tccagcacga ttgccaatgc cagccaggcg
     3481 gcgtgaaccc attcaaactg cgccatggtt cacctccagt tcaggtttac gcgctttacg
     3541 ggtacctgac ttgatcaaca caatcccggc caccagggtg gttaacccgg caattttcat
     3601 cagcgataaa ctttcgtcga ataacaaaac gctaaacaag gtaataaata aaataccaat
     3661 accttcccac agcgcataag ctacgcctaa ggcgattttt ttaacggcga aagagagaaa
     3721 tatatacgac agagaaatca tcaccagcat taaaataaag ccgccatttc cctcactgac
     3781 gctcgcccat ttcattgaca gcgtaccggt aatttccgta gcaatagcca ggcctaataa
     3841 aatccaataa atatacattg tccttctcct gcaagagaat tattttaatt ttcgcttaat
     3901 tcagcgaaac caaagtaaag tgatcaagcc ccgcgcatag cgcaagctta ggcagaagaa
     3961 aggactaaag cgcgttgcgc cagtgctgct cacctacgag caagatagtg gatgaggtac
     4021 gaagatgggt aaatgtagaa aataacgtcc tgaacaaatt gtccataata ttacaattat
     4081 ccgcagtgtt gcttctcgtc atcgcggatg ataattgtcc tcggtagttg aacacgcctg
     4141 atttgtatca tagcttaaga attaactcaa aatattttca cttctttacc tgagcggttt
     4201 gattttcgtt atgatgaagg agcgaaaaag acattattat tagcaaagga agaaaaaacg
     4261 gggacaagca tggcaaagcc gatcatcacg ctcaatggcc taaaaatcgt cattatgttg
     4321 ggaatgctgg tcattattct ctgcggtatc cgttttgccg ccgagattat cgtgccgttt
     4381 attctcgcat tatttattgc tgttattctt aacccgctgg tgcaacacat ggtccgctgg
     4441 cgtgtgccgc gtgtactggc agtgtcgatt ttgatgacca tcatcgtgat ggcgatggtg
     4501 ttgctgttag cttatctggg gtccgcgctc aatgagttga cgcggacgtt accgcaatat
     4561 cgcaactcta ttatgacgcc gctgcaagcg attgaaccgt tgttgcaacg cgtagggatt
     4621 gatgtctcag ttgaccaact ggcgcattac attgatccga acgcggcgat gacgttgctc
     4681 accaacttat tgacgcagtt atctaatgcc atgtcatcaa tctttttatt gctgctgacg
     4741 gtgctgttta tgttgctcga agtgccacaa ttgcccggaa aatttcagca aatgatggcg
     4801 cgtccggttg aagggatggc ggcgattcag cgcgcgattg acagcgtgtc tcattatctg
     4861 gtgctgaaaa cagccatcag catcatcacc ggcctggtcg cctgggcgat gctcgccgca
     4921 ctcgatgttc gcttcgcttt tgtctgggga ttgctggcct ttgcgcttaa ttacatcccc
     4981 aatattggtt cagttctcgc ggcaatcccc cctatcgctc aggtactggt gtttaatggc
     5041 ttctacgaag cgttgctggt gctggcggga tatctgctga ttaatcttgt cttcggcaat
     5101 attctggagc cgcgcatcat ggggcgtggg ctggggcttt ccacattggt ggtatttttg
     5161 tcgttgattt tttggggatg gttgttagga ccggtgggta tgctgctttc cgtgccgttg
     5221 acaattattg tcaaaattgc gcttgaacaa acagcgggag gtcaaagcat cgccgttctg
     5281 ttaagcgatc tcaataaaga gtgacggcct ccgcagaggc cgtcagggtt acagagcttt
     5341 caggattgca tccacgctgg ctttggcgtc accaaacagc atgtgggtgt tttccttgaa
     5401 gaacagcggg ttttgcacac cagcatagcc agtgttcatc gaacgtttaa agacaatcac
     5461 gttctgcgct ttccacactt ccagcacagg cataccagca atcggactct tcggatcatc
     5521 ctgcgccgcc gggttaaccg tatcgttagc accaatcacc agtacggtat cggtatcagc
     5581 aaagtcatcg ttgatctcgt ccatttccag cacgatgtca tacggtactt ttgcttcagc
     5641 cagcaatacg ttcatatgtc caggcaaacg ccccgcaacc gggtggatac cgaaacgcac
     5701 gttaatacca cgagcgcgca atttctcagt aatttcagcg acaggatatt gcgcctgcgc
     5761 aactgccatg ccgtaccccg gagtaatgat cactgaatgg gaatttttca gcagttccgc
     5821 tgtctcttct gcggtgattt cgcggtgctc gcccacttcc tgatcatcac cagtagaaga
     5881 gccgtcggtg ccgaaaccgc ccgcaataac gctgataaag gaacggttca tcgccttaca
     5941 cataatgtaa gaaaggatag cccccgaaga accgaccagc gcaccggtca caatcagcag
     6001 gtcgttgctg agcataaagc ccgcagccgc agccgcccag ccggagtacg agttcagcat
     6061 cgacaccacc actggcatat ctgcaccacc gatggaggcg actaaatgcc agccgaatac
     6121 cagcgcaatg gcggtcatta tcagcaatgc cagcacttgc aggccgacgc tatccgtgcg
     6181 aacaaataca atcagcagca ggaaggaaac gatcagagcc gccaggttca ttttgtgacg
     6241 gtttggcagc atcaacggtt tagacgaaat cttgccacac agtttgccga acgccaccac
     6301 cgaacccgta aacgttaccg ccccgatgaa gataccgagg aacacttccg tcaggtgaat
     6361 attgaccaga atcggtgcca ttcccgcgtc atgatgcaga tagctgttaa aaccaaccag
     6421 cactgccgcc agacccacga agctatgcag gatcgccacc agttctggca tttcggtcat
     6481 ttcaactttc ttcgccagac ggataccaat tgccccacca ataaccatcg ccagcaagat
     6541 ccagccaaca ttacccgtat ccggtccaaa aatggttgcg attaacgcaa tcgccatacc
     6601 ggcgataccg aaattgttac cctggcgaga cgtttcatgt ttcgaaagcc cggccagact
     6661 gaagataaac aggatcgcgg caacaatgta tgcagctgta actaatcctc cagacatatg
     6721 ttacccctta atttttgcgg aacattttca gcatgcgctg agtcacggtg aagccaccga
     6781 aaatattaat gctggctata agcaccgcga taaaactaag gaagctaacc cagccgccct
     6841 ggccaatctg caacagtgct ccgacaacaa taatccctga aatcgcgttg gtgaccgaca
     6901 tcaacggtgt atgcagcgcg tgcgatacat tccacaccac gtaataaccg acaacgcagg
     6961 ccagcgcgaa cacagtgaag tgtccaagga actcttttgg cgcaacgctt gccatccagc
     7021 cgaaaaggat gattgccaac gccatcaacg cgtatttacg ccacggtgag caggcacatt
     7081 tttcctcagt tttcacttcc ggtgccgctt tttgtgccgt ctgcggctga gctgatacct
     7141 gaatcggcgg tgccggccag gtaatttcgc ccgcacggat cacagtcacg ccacgaatca
     7201 ccacatcatc aaaatccaca gtgatgttgc cgtctttctc tttgcacaac agtttcagca
     7261 gattaacgag gttagtgccg taaagctgtg aggattgcgt cggcagacgg cccggaagat
     7321 cggtgtaacc aattactttg acaccatttt ccgtagtgaa gatttcaccc ggcacggtgt
     7381 attcacagtt gccgccgttt tgggctgcca ggtcgacaat cacactgccc gccttcatgg
     7441 agtcaaccat ttcacgggta attagcttcg gcgctggttt gcctggaata agcgcggtgg
     7501 tgacaatgat atcgacctct tttgcctggg cggcaaagag ttccatttcc gctttgatga
     7561 acgcgtccga catcactttg gcatagccat cgccgctgcc cgcttcctct ttaaaatcca
     7621 gctcgaggaa ttctgcgccc atactttgaa cttgttcttt cacttccggg cgggtgtcga
     7681 atgcacgcac aatcgcgccg agactgtttg ctgcgccaat ggcggccaga cctgcgacac
     7741 cggcaccaat caccatcact tttgccggtg gcactttccc ggccgcagtg atttgtccgg
     7801 taaagaagcg cccaaattca tgtgccgctt caacaatggc gcgataaccg gcgatattcg
     7861 ccatcgagct tagtgcgtcc agcgattgtg cgcgtgagat acgcggcaca gagtccatcg
     7921 ccatcacggt cacgttacgt tccgcaagtt tttgcattaa ttccggattc tgcgcaggcc
     7981 agataaaact caccagcgtt gtcccaggat tcagtaacgc aatttcatca tctaacggcg
     8041 cattgacctt cagaatgatc tctgactgcc agacgctatt cccttctaca atttcagcgc
     8101 ccgcttgcac aaacgcctta tcgtcaaaac ttgccagttg acccgcgccg ctctctaccg
     8161 cgacggtaaa acccagtttc agcagctgtt ccactgtttt tggcgttgct gcaacacggg
     8221 tttcattggt taaccgttct cttggtattc caattcgcat gatattccct tccatcggtt
     8281 ttattgatga tggtttgctt gtgtcaggag ccacacaagc cgctcatgta cgagctaaat
     8341 gttactccgt taaaataaat tagtaacaaa cgccctataa cgtactgaaa attatgcctg
     8401 tgatctagcg ccaaaaatca gtatttcggc gtgaactcgc aaaatattaa cgattcagcc
     8461 gtgatagtgg gataaacacc ttagaacgcc ggataaagac tgataattgt cttcggcggc
     8521 cgggtaaaac gagacatcgc cccggcacaa atcactactt aacattaaat taacttatac
     8581 aattcagttg cttcagtagt attgatggtg atacggctgt tttttaagca tagacggtca
     8641 tttgagcaga attaaaattg gtttaaggaa tgtgatatga aaaatgacgc agacagttac
     8701 accgtttaaa tgcaataatc agccacgttt ctcgttaata acaataccag tacctggttt
     8761 gcgcaaggcg aaggattatt tttatgaagc ttaagaacac cctcctggcg tcggcactgc
     8821 tttctgctac ggcattctcc gttaacgcag caacagaact gacaccggag caagcggcag
     8881 cggttaaacc ttttgaccgt gtagtggtta ccggtcgttt taatgctatt ggcgaagcgg
     8941 tgaaagccgt ttctcgtcgc gcagataaag aaggtgccgc ctctttttat gttgtcgaca
     9001 cttctgattt tggtaacagc ggtaactggc gtgtggtcgc tgacctctat aaagccgatg
     9061 ctgaaaaagc agaagaaaca agtaatcgcg taattaacgg tgttgtcgaa ctgccgaaag
     9121 atcaggctgt tctgattgaa ccgtttgaca cggtcaccgt ccagggcttc tatcgtagcc
     9181 agccagaagt caatgatgcc atcaccaaag cggcaaaagc gaaaggtgcc tactctttct
     9241 acattgttcg tcaaatcgat gccaaccagg gcggtaacca gcgtattact gcattcatct
     9301 ataaaaaaga tgctaagaaa cgtatcgtcc agagcccgga tgtaatcccg gcagattccg
     9361 aagcaggacg tgcagctctg gctgccggtg gcgaagccgc gaagaaagtt gagatcccgg
     9421 gtgttgcgac taccgcatca ccaagttctg aagtcggtcg cttctttgaa acccagtcat
     9481 caaaaggcgg gcgttacacc gtcacgctcc cggatggcac taaagtcgaa gaactgaaca
     9541 aagcgacagc agcgatgatg gtcccgttcg acagcatcaa attctctggc aactacggca
     9601 acatgaccga agtctcctat caggttgcga aacgtgccgc gaagaaaggt gctaagtatt
     9661 accacatcac ccgccagtgg caggaacgtg gtaataacct gaccgtcagc gcagatctgt
     9721 ataaataact attcagttac tcctataagg cggcttgatg ccgcctttcg catttttagt
     9781 cataaatttc cctgcgacca ttgcatgcag acacatctct tcgtaaaatc ccgcgcttca
     9841 gtggcaaact ccatttttat gcgttttgcc ctaatattta ttcttcttgt cacgttttaa
     9901 tcactggata tcgatggaaa agaaactggg actgagcgca ctcaccgcgc tggtattaag
     9961 ctcaatgctg ggcgcgggtg ttttcagtct gccgcaaaat atggcggcag ttgccagccc
    10021 ggcagcactg ctcatcggct ggggtattac tggcgctggc attttattgc tggcctttgc
    10081 catgctgatc ctcacgcgca ttcgccccga acttgacggc ggtatcttta cctatgcccg
    10141 cgaagggttt ggcgagctaa tcggcttttg ttccgcatgg ggatactggc tgtgcgcggt
    10201 catcgccaac gtctcctatc tggtgatcgt tttttccgcg ttaagctttt ttacggacac
    10261 gccggaattg cgcctgtttg gcgatggtaa tacctggcaa tcgatcgtcg gtgcatcggc
    10321 tttattgtgg attgttcact ttttgatcct gcgcggggtg caaaccgctg ccagcattaa
    10381 ccttgtggcg acactggcaa aattgttgcc gttgggtctg tttgttgtgc tggcgatgat
    10441 gatgttcaaa ctggatacct tcaagctcga cttcaccgga cttgcacttg gcgtacccgt
    10501 gtgggaacag gtgaaaaaca ccatgctgat caccctgtgg gttttcattg gtgtggaagg
    10561 tgccgtggtt gtttctgcgc gtgcgcgtaa taagcgtgat gttggcaaag cgacactgct
    10621 ggcggttctc tccgctctgg gcgtttattt gctggtaacg ctgctttcgc tgggcgtggt
    10681 ggcacgtcct gaactggctg aaattcgtaa cccgtcaatg gccggtctga tggtggaaat
    10741 gatgggaccg tggggcgaaa tcatcatcgc tgccggtttg atcgtttccg tttgcggcgc
    10801 gtacttaagc tggaccatca tggcagcaga agttccgttc cttgcagcca ctcataaagc
    10861 attcccgcgc atttttgcgc gccagaacgc acaagctgcg ccatccgctt cactgtggct
    10921 gaccaacatc tgcgtgcaaa tttgtctggt gctcatctgg ctgaccggtt ccgattacaa
    10981 cacattgctg accatcgcct cagaaatgat tctggtgccc tatttcctgg tcggcgcgtt
    11041 cttgctgaaa atcgcaaccc gtccactgca taaggcggta ggtgtcggtg cctgcattta
    11101 tggcttatgg ttactgtacg cctctggtcc aatgcacttg ctgttatccg ttgttctgta
    11161 tgcgccgggg ctgctggttt tcctgtacgc gcgtaaaacg catacacatg ataatgtact
    11221 gaaccgtcag gaaatggtgc tgattggcat gctgttaatt gcctcagttc cggcgacctg
    11281 gatgctggtg ggataacgtt catcccatcg ttggatagca aaggagataa cgatgggtaa
    11341 aacccagtcc ttgccaatat taattactgg cggaggtcgc cgcatcggcc tcgccctcgc
    11401 atggcatttc attaatcaaa agcaaccggt gattgtcagc tatcggacgc actatcccgc
    11461 cattgatgga ctgattaagg caggtgcgca gtgtattcag gctgattttt cgaccaacga
    11521 cggtgtgatg gcgtttgccg atgaagtact aaaaagcacc catggtctgc gtgctatttt
    11581 gcataacgcc agcgcgtgga tggcggaaaa accgggagcg ccactgaccg acgtactggc
    11641 ttgcatgatg cagatccacg ttaatacccc atacctgctc aaccatgctc tggaaagatt
    11701 actgcgtggg cacggacacg ccgccagcga tatcattcac tttaccgatt atgtggtgga
    11761 gcgcggtagc gacaaacata ttgcctatgc tgcaagcaaa gcggcactgg ataatatgac
    11821 ccgctcgttt gcccgcaagc tggcaccgga agtgaaagtg aattctattg cgccatcgct
    11881 gatcctgttt aatgaacatg atgatgccga atatcgacaa caggcgctga ataaatcact
    11941 gatgaaaacc gcgcctggcg agaaagaagt gatcgacctg gtcgattact tacttaccag
    12001 ctgctttgtc accggacgca gtctcccact tgatggcggt cgtcatctgc gttaatgcag
    12061 cttaatccag catataatca acacccatgc gcttattccc cagcacgcaa cagagccaac
    12121 aaaagcagcg ggcaagcgca tcattccggt gaaataccat agcgacgcca ggtaaacaaa
    12181 atagggaata atcgaccaca tactaaaaat gatggttgcg cgtaaggctt caatgccgcg
    12241 ttcgctggca acaatataat gcgcgataag cgcaaaggtc gggaaaagtg gaatcagccc
    12301 ggcgatataa taatttttcg tttttgctaa aacaccaatc aacagcacta ccagcgcacc
    12361 gagcgcggct ttgattacca gccccatctt tttaccttaa cacttccata acaagtcatc
    12421 agtagaatac ctgatgaaac cttgtttaga aacgattgat agtaagtaaa aacagtgcgg
    12481 tgtattgtga cgtttttata tctaccgtga atgttatgaa cactatcgta tttgtggaag
    12541 atgatgcgga agtcggtgca ctgattgccg catacctggc aaaacatgat atgcaggtta
    12601 ccgtagagcc gcgcggcgac cgggccgaag aaactattct gcgagaaaat ccggatttgg
    12661 tgttactcga catcatgcta ccaggcaagg acggcatgac catttgtcgt gatttacgcg
    12721 caaagtggtc cggaccgatt gttcttctaa cctctctcga tagcgatatg aaccacatcc
    12781 tggcactgga aatgggcgcc tgcgactata ttctcaaaac gacgccccct gctgttttgt
    12841 tagcgcgttt acgcttgcat ttgcgtcaga atgagcaagc cacagtgacc aaaggtattc
    12901 aggaaacgtc tctgactccc tacaaagccc tgcatttcgg cacgttgacc atcgatccca
    12961 tcaaccgcgt agtctccctg gctaacactg aaatctcgct ctcgacagct gatttcgaat
    13021 tattgtggga attagctacc catgccgggc aaatcatgga ccgcgatgca ttgctgaaaa
    13081 atttacgcgg cgtcagttat gacgggctgg atcgtagcgt ggacgtggct atttcgcggt
    13141 taagaaaaaa actgctcgat aacgccgcag aaccttatcg tattaaaacc gtgcgtaaca
    13201 aaggctatct ttttgcgcct catgcgtggg aataagcgat gaaaaaactg tttatccagt
    13261 tttacctgtt attgtttgtc tgcttccttg tgatgtctct gctggtcggg ctggtgtaca
    13321 aatttaccgc cgaacgcgca ggcaaacagt cgctggatga tttgatgaac agttcgctgt
    13381 atctgatgcg cagcgaattg cgtgagatcc ccccacacga ctggggtaag acgctgaaag
    13441 agatggattt aaatctctct ttcgatctgc gtgtcgagcc gctgagtaaa tatcatcttg
    13501 atgatatttc catgcaccgg ctgcgtggcg gcgaaattgt cgctctggac gatcagtaca
    13561 cttttttgca acgtatccca cgcagccact acgtgctggc agttggtcct gttccttatc
    13621 tttattacct ccatcagatg cgattgctgg atatcgccct gatcgctttt attgccattt
    13681 ccctcgcctt tccggtgttt atctggatgc gtccgcactg gcaggatatg ttaaaactgg
    13741 aagcagcggc gcaacgattt ggcgatgggc atctcagtga gcgtatccac tttgatgaag
    13801 gttcgagctt tgaacgactt ggcgtcgcat ttaaccagat ggcggacaat atcaacgcct
    13861 tgattgccag caaaaaacag cttattgacg gtatcgctca cgaactgcga acaccgttag
    13921 tgcgcctgcg ttatcgactg gagatgagcg ataacctgag cgccgccgaa tcccaggcgt
    13981 tgaatcgcga tatcagtcaa cttgaagctt taattgaaga gctgctgact tatgcccggc
    14041 tcgatcgccc acaaaatgag cttcatctta gcgaaccaga cctgccgttg tggctgtcaa
    14101 cgcatctggc agatattcag gcagtaacgc ccgataaaac ggtacggata aaaacgctcg
    14161 cgcaaggcca ttatgctgcg ttggatatgc gcttaatgga gcgcgtgctg gataatttgc
    14221 tcaataacgc cctgcgctac tgtcactcaa cggttgaaac cagcctgcta ctgtcgggga
    14281 atagagcgac attaattgtt gaggatgatg gcccagggat tgccccagaa aaccgcgaac
    14341 atatctttga accttttgtt cgcctcgatc ccagccggga tcgctcaacc ggcggctgcg
    14401 ggctggggct ggccattgtc cactctatag cactggcaat gggcggtacg gttaattgtg
    14461 acaccagcga actggggggt gcccgcttct cgttcagctg gccgttatgg cataacatcc
    14521 cgcaatttac ctctgcctga cactatgcgc acggtggtca agtcaccacc actgtgctat
    14581 aaaataagga tgttgtaact aaagtgatta atattatggc gcgttacgat ctcgtagacc
    14641 gactcaacac tacttttcgc cagatggaac aagagctggc tgcatttgcc gctcatcttg
    14701 agcaacacaa gctattggtt gcccgcgtgt tctctttgcc ggaggtaaaa aaagaggatg
    14761 agcataatcc gcttaatcgt attgaggtaa aacaacatct cggcaacgac gcgcagtcgc
    14821 tggcgttgcg tcatttccgc catttattta ttcaacaaca gtccgaaaat cgcagcagca
    14881 aagccgccgt ccgtctgcct ggcgtgttgt gttaccaggt cgataacttt tcgcaagcag
    14941 cgttggtcag tcatattcag cacatcaata aactcaagac cacgttcgag catatcgtca
    15001 cggttgaatc agaactcccc tccgtggcac gttttgaatg ggtacatcgt cattttccgg
    15061 ggctgattac ccttaatgct taccgcacgc tcaccgttct gcacgacccc gccactttac
    15121 gttttggctg ggctaataaa catatcatta aaaatttgca tcgtgatgaa gtcctggcac
    15181 agctggaaaa aagcctgaaa tcaccacgca gtgtcgcacc gtggacgcgc gaggagtggc
    15241 aaagaaaact ggagcgagaa tatcaggata tcgctgccct gccacagaac gcgaagttaa
    15301 aaatcaaacg tccggtgaag gtgcagccga ttgcccgcgt ctggtataag ggagatcaaa
    15361 aacaagtaca acacgcctgc cctacgccgc tgattgcgct gattaatcgg gataatggcg
    15421 cgggcgtgcc ggacgttggt gagttgttaa attacgatgc cgacaatgtg cagcaccgtt
    15481 ataaaccaca ggcgcagccg cttcgtttaa tcattccacg gctgcacctg tatgttgcag
    15541 attaaccccc ggctttcata ctgccgacca tctgttctgg ccgtacccag cggtcaaact
    15601 cggcttcgct aagatacccc agcgcaaggg ccgccgcttt taaggtcagc ccttctttat
    15661 gcgccttttt ggcgatctcg gcggctttgt cataaccaat gtgggtgtta agcgcagtca
    15721 ccagcatcag cgattcattg agtaattgat tgattcgctc acgattcggt tcaatgccca
    15781 ctgcgcagtg tttgttgaaa ctttccatgc catctgccag caagcgcacc gattgcagga
    15841 aattatggat caccatcgga cggaagacgt tcagttcaaa gttaccggaa gcgccaccca
    15901 tgttgatcgc cacgtcattc cccatcacct gacagcagag catggttaat gcttcacact
    15961 gtgttgggtt cactttccct ggcatgattg agctgcccgg ctcattttcc gggattgaga
    16021 tttcaccaat tccgcagcgc gggccagagg ccagccagcg gacatcattg gcaattttca
    16081 tcagtgacgc agccaaccct ttcaacgcgc cgtgcgcctg aaccagggca tcacaggtcg
    16141 ccagcgcttc aaatttgttc ggtgcggtaa caaacggtgc acaggtaatg actgccagtt
    16201 catctgctac gcgacgcgca tattccggat gggtatttag tccagtaccc accgctgtac
    16261 cgcccagagc cagttccgct acgtgaggca ggctgtattc gatatgtttg agattatgct
    16321 ccagcatcgc tacccagccg gaaatctcct gccccagcgt taacggcgtg gcgtcctgca
    16381 agtgggtacg accgattttg acgatatcag caaatgcgcg ggatttttca ctcagcgtct
    16441 gggtcagggt tttaagttgt ggaatgagtt gcttgcgcag cgccagtagt gccgcaacgt
    16501 gcatcgccgt cggaaagaca tcgttggaac tttggctttt gttcacgtcg tcgttagggt
    16561 gaactttacg ttccatcccg cgcacgccac cgagtaattc actggcccgg ttagccagca
    16621 cttcgttcat attcatgtta ctttgcgtgc cggagccggt ctgccagata gccagcggga
    16681 attcgtcgtc atgctgtcct gccagtactt catccgccgc ctgccgaatg gcgctcgctt
    16741 tctcttcaga caacaagcct aaatcttcat taacttttgc cgctgcgcgc ttggttagcg
    16801 ccagcgcatg aatcagtgag gtgggcattt tctccgtcga aatgcggaaa tgctccagcg
    16861 agcgctgagt ttgtgcgccc cacagcttat ctgccgggac atcaatcgct cccatcgaat
    16921 ctttttcgct gcgtactgta ttcatggcct gctcctcacc tgattaattt tttctttctg
    16981 ttttgctttc gttaagcaac ttttagctca ctcattattt accatttgat aacaaacgtt
    17041 tggtctttcg tgccatgtaa aaaaaccgcc ccgaagggcg gctctgttta tttcacacaa
    17101 cgggtgcatt gtgtgagttg tatctgctgg aagaagtcat ttcctttatc atccacaagg
    17161 ataaacgccg ggaaatcttc cacttcaatt ttccagatgg cttccattcc cagttccgga
    17221 tattcaacac attccaggct cttaatactt ccctgcgcca atacagctgc cggaccaccg
    17281 atactgccga ggtagaagcc gccgtgtttt ttacaggcat ccgtcacctg ctggctgcgg
    17341 ttgcctttcg ccagcatgat catacttccg ccctgcgctt gcagttgatc gacataagaa
    17401 tccatccgtc cggcggtcgt tgggccaaga gaaccggagg cataaccttc cggcgttttg
    17461 gccggacccg cgtagtaaat cggatgatct ttaatatact gcggcagccc ttcaccgtta
    17521 tccatccgct ctttcagttt ggcgtgagca atatcacgac cgacgataat cgtgccgtta
    17581 agcgataagc gtgtagaaac gggatactgc gacaactgtg cgaggatctc tttcatcgga
    17641 cggttgaggt caacgcgcac cgcttcgcct tctcctgctt tgcgcagctc ttccgggata
    17701 tatttgcctg gattatgttc cagtttttcg atccagatcc cctgacggtt gatcttcgct
    17761 ttgatattac ggtcagcaga acaggagacg cccataccga ccgggcagga tgcgccgtga
    17821 cgtggcaggc gaatcacgcg gatgtcatga gcgaagtatt taccaccaaa ctgcgcaccc
    17881 agaccaagat tttgcgcttc gatcagcaat tctttttcca gttccacatc gcggaacgcc
    17941 tgaccgtgct cattcccttc cgttggcagt tcatcatagt atttagcgga agccagtttc
    18001 accgttttaa gattcgtttc tgcagaagtt ccaccaataa cgaacgcaat atgatacgga
    18061 ggacaggccg ccgtacccag cgtgcgcatc ttctcaacca ggtaattttt cagttttccc
    18121 ggcgtcagta acgctttggt ttcctgatag agatacgtct tgtttgccga accgccacct
    18181 ttggcgatac agaggaattt gtactcgtcg ccatcaacgg cataaagatc gatctgcgct
    18241 ggcaagttgg tgccggtatt cacctcttta tacatatcca gcggcgcgtt ttgcgagtag
    18301 cgcagattat cctcgatata agtgttataa acaccgcgcg ccagcgctgc ttcatcaccg
    18361 ccaccggtcc atacacgctg ccctttttta ccaacaataa tcgcggtgcc ggtatcctga
    18421 caggttggca gaacgccttt tgccgcgatg tcggagttac gcaggaattg cagcgccaca
    18481 tatttatcat tttcgctggc ctccgggtca cacagaatgt cggccacctg ttgttggtga
    18541 gccggacgca gcataaatga cgcatcatga aacgcctgac gcgccaacag agttaacgct
    18601 tcgggtgcga ctttcaaaat ctcctgccct tcaaattcag atacgctaac gtgttcgctg
    18661 gttagcaggt aatactcagt atcatctttt ttgagtggaa aaggagcctg ataatgaaag
    18721 ggtttgtttg acattgttct ctcacttact gcctggtttg gttatgctct gggcgggtgt
    18781 tccgttgccc tgttaaaagc gagtaacaat atcctacaca cttttttaac aaaaactgag
    18841 actagtacga ctttttgcgg ctccaggtta cttcccgtag gattcttgct ttaatagcgg
    18901 gattaatttc cacattaaaa cagggattga tcatgcaaaa actcattaac tcagtgcaaa
    18961 actatgcctg gggcagcaaa acggcgttga ctgaacttta tggtatggaa aatccgtcca
    19021 gccagccgat ggccgagttg tggatgggcg cgcatccaaa gagcagttca cgtgtgcacg
    19081 atgccgcagg agatatcgtt tcactgcgtg atgtgattga gagtgataaa gcgactcttt
    19141 tgggagatgc cgttgccaaa cgctttggcg agttgccttt cctgttcaaa gtattatgcg
    19201 cagcccagcc gctctccatt caggttcatc caaacaaacg caattctgaa atcggttttg
    19261 ccaaagaaaa tgctgcaggt attccgatgg atgccgctga gcgtaactat aaagatccta
    19321 atcacaagcc tgagctggtt ttcgccctga cccctttcct cgcgatgaac gcgtttcgtg
    19381 agttttccga gattgtctcc ctgctccagc cggtcgcagg tgcacatccg gcgattgctc
    19441 actttttaca acagcctgat gccgaacgtt taagcgaact gttcgccagc ctgttgaata
    19501 tgcagggtga agaaaaatcc cgcgcgctgg cgattttaaa atcggccctc gacagccagc
    19561 agggtgaacc atggcaaacg attcgtttaa tttctgaatt ttacccggaa gacagcggcc
    19621 tgttctcccc gctgttgctg aatgtggtga aattgaatcc tggcgaagcg atgttcctgt
    19681 tcgctgaaac accgcacgct tacctgcaag gcgtggcgct ggaagtgatg gcgaactccg
    19741 ataacgtgct gcgtgcaggt ctgacgccta aatacattga tattccggaa ctggttgcca
    19801 acgtgaagtt cgaagccaaa ccggctaaca agttgttgac ccagccggtg aaacaaggtg
    19861 cagaactgga cttcccgatt cctgtggatg attttgcctt ctcgttgcat gaccttagtg
    19921 ataaagaaac caccatcagc cagcagagtg ccgccatttt gttctgcgtc gaaggcgatg
    19981 caacgctgtg taaaggttct cagcagttac agcttaaacc gggtgaatca gcgtttattg
    20041 ccgccaacga atcaccggtg actgtcaaag gccacggccg tttagcgcgt gtttacaaca
    20101 agctgtaaga gcttactgaa aaaattaaca tctcttgcta agcttattaa aggcttataa
    20161 caccttcagg cggccagtcc gcctgatttc attttatgga taatcattat gaataaatcg
    20221 ctggtagcgg taggcgtcat tgttgcgcta ggcgtagtct ggacaggcgg cgcatggtat
    20281 acaggcaaga agattgaaac ccatctcgaa gacatggtcg cgcaggcgaa cgcgcaactc
    20341 aaactgacag ctcctgaatc caacctggaa gtcagttatc aaaactatca tcgcggcgta
    20401 ttcagcagcc agttgcaact gttggtgaaa cccattgccg gaaaagtaaa tccgtggatt
    20461 aaaagcggtc agagcgtcat cttcaacgaa tcggttgatc atggtccctt cccgcttgcc
    20521 cagcttaaaa aactgaatct gatcccgtcg atggcatcaa ttcaaaccac gctggttaat
    20581 aacgaagtaa gcaaaccact gtttgatatg gcaaaaggtg aaacgccttt tgagattaac
    20641 tcccgcattg gttacagcgg agattccagt tccgacattt cgctcaagcc actgaattac
    20701 gagcaaaagg atgaaaaagt cgcctttagc ggcggcgagt tccagttaaa tgcagacaga
    20761 gacggcaaag ctatctccct ttccggggag gcgcaaagtg gtcggataga cgcggttaac
    20821 gaatacaacc agaaagtgca gttaaccttt aataatctga aaaccgacgg ttccagcacg
    20881 ctggcaagtt ttggtgagcg cgtaggaaac caaaaactgt cgctggaaaa aatgaccatt
    20941 tcagtggagg gcaaagaact ggcactgctg gaaggcatgg agatcagcgg taaatcggat
    21001 ctggtcaatg acggtaaaac gatcaatagc caactggatt actcgctaaa cagcctgaag
    21061 gtacagaatc aggatctggg cagtggcaag ctgactttaa aagtcggcca aattgatggc
    21121 gaagcctggc atcagtttag ccagcaatat aacgcgcaaa ctcaggcgct gctggcacag
    21181 ccagaaattg ccaacaatcc cgaactttat caggagaaag tgacggaagc cttctttagc
    21241 gctctgccgc tgatgctgaa aggcgatccg gtgattacta tcgcgccgct aagctggaaa
    21301 aacagtcagg gtgaaagtgc gctgaatctg tcgctgttcc tgaaagatcc ggcaacgact
    21361 aaagaagcgc cgcaaacgct ggcgcaggaa gtggaccgct cggttaaatc tctggatgcg
    21421 aaactgacca ttccggtgga tatggcaact gagttgatga ctcaggtagc gaagctggaa
    21481 ggttatcagg aagatcaagc gaaaaaactg gcgaaacagc aagttgaagg tgcatcagca
    21541 atggggcaga tgttccgtct gaccaccttg caggacaata ccatcaccac cagcctgcaa
    21601 tatgctaacg gtcagataac gttaaacggg cagaaaatgc cactggaaga tttcgtgggt
    21661 atgtttgcga tgccgacatt aaacgttccg gctgtacccg ctattccgca gcagtaattc
    21721 acagccaaaa cgccggagat ttttctctcc ggcgtttttt cttacttcag cataaagtca
    21781 tactgaatac tcattttcac atcccagtaa ttcaggcgat cgcccagcgt actgccatcg
    21841 cgcttttccc gtcctttatc ggcagcaaga aagaaattca tcccttgtaa cggcccttcg
    21901 ctgacccgat agttcatacc ccctaagata cccgctcctt caatccgcac atctcgttta
    21961 ctggattcat agccgcgggt cacaatcggt gcaaatgtca gcgtaaattg cggagttaaa
    22021 cgatagttga cgcccaattg ccaggactgc attccttcac ggttacgatc aagacttaat
    22081 gaaaagggat agccaatgtc ggtatccacc acggcaccat tcattgcatg gcgcaaataa
    22141 ccaccactgc caaatacgct tccccacggc gcattccagg tcaattgtcc actaaccaac
    22201 gccgtttcat tgggctggct ggtattacga cttaaacctt caagttgcgc gtaaaagccg
    22261 agcaactccc ctttcaacgt ataattcggg tcaagcggta tgcttttctc gagaatactt
    22321 tgtatctgat tggaaacatc tttctgtacc gatgccccca gagaatagcg actggtatca
    22381 tcatgccaac tggcggctaa aaaagaacgt gcgcgatgtt tatcgtattt tcccgtctgg
    22441 ctgttataaa caccttcatc acgaataccg gttgttgaat cggtccataa aaatactcgt
    22501 gaacgccaca ttccccacag atcaatattt ggcgttaaag cccaataacc taatgctcct
    22561 tcagaaacag tcggtaatgt acgttgcgaa ctgccagcca ttaacggaat acgataaggt
    22621 aagctaccat aactataatc cgtcccgaag cgacctaatt ttagcaggct attttcactg
    22681 ggttttattt ttactgcccc cagggcaaag ccaaaacttt tatcaccatc aagataccac
    22741 cgggtactca tatcagcacg agcacctaat ttataaacat aatacgcccc gccttcaacg
    22801 ccaataatta ttggaataat aaccactatt gaaatcgagc aatcctccct gtacccatgc
    22861 gtaaatatct cttcccgtgc cagcactggg cttatcagcc ctgcgtaatt cgtttttcag
    22921 tctgatgcgt agtcccgctt catcgtcagc cagttgtgcc gcgtaagcag ag
//
LOCUS       DAFGPF010000077        22359 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFGPF010000077 DAFGPF010000000
VERSION     DAFGPF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22359
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.077"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(275..1186)
                     /gene="gsiD"
                     /locus_tag="LSX49_003317"
     CDS             complement(275..1186)
                     /gene="gsiD"
                     /locus_tag="LSX49_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HBL7169691.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(1189..2109)
                     /gene="gsiC"
                     /locus_tag="LSX49_003318"
     CDS             complement(1189..2109)
                     /gene="gsiC"
                     /locus_tag="LSX49_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HBL7169692.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGILLIQVFSVELG
                     WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            complement(2127..3665)
                     /gene="gsiB"
                     /locus_tag="LSX49_003319"
     CDS             complement(2127..3665)
                     /gene="gsiB"
                     /locus_tag="LSX49_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HBL7169693.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKEVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGLTYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFHPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQAALLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESCVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            complement(3685..5556)
                     /gene="gsiA"
                     /locus_tag="LSX49_003320"
     CDS             complement(3685..5556)
                     /gene="gsiA"
                     /locus_tag="LSX49_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HBL7169694.1"
                     /translation="MPHSDELDAGDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQSAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEHPAKQESSIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVT
                     REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLS
                     PGKLQALRRDIQFIFQDPYASLDPRQTIGDSILEPLRVHGLLPGKEAAARVAWLLERV
                     GLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD
                     LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAA
                     VPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR"
     gene            complement(5543..6508)
                     /gene="iaaA"
                     /locus_tag="LSX49_003321"
     CDS             complement(5543..6508)
                     /gene="iaaA"
                     /locus_tag="LSX49_003321"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL7169695.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLV
                     AGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACLMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFAHGMERVSPEIFSTPLRYEQLMAAREEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            6712..7947
                     /gene="moeA"
                     /locus_tag="LSX49_003322"
     CDS             6712..7947
                     /gene="moeA"
                     /locus_tag="LSX49_003322"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBL7169696.1"
                     /translation="MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDV
                     VSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQTDNGVRFTAEARSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASPLKKSPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VEVGEWVEVEPFNALFGGL"
     gene            7947..8696
                     /gene="moeB"
                     /locus_tag="LSX49_003323"
     CDS             7947..8696
                     /gene="moeB"
                     /locus_tag="LSX49_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HBL7169697.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLVVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIA
                     ITPVNALLDDAELAAMIAKHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(8772..9434)
                     /gene="fsa"
                     /locus_tag="LSX49_003324"
     CDS             complement(8772..9434)
                     /gene="fsa"
                     /locus_tag="LSX49_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBL7169698.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAVGKKPLEVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDARKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRT
                     SI"
     gene            9565..10464
                     /locus_tag="LSX49_003325"
     CDS             9565..10464
                     /locus_tag="LSX49_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBL7169699.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDPRLCLEGCELCAKTAPEVIERALNGLLIHREKLTPEHFTALTDCCPTQALTVCGE
                     VKSVEEIMATVLRDKPFYDRSGGGLTLSGGEPFMQPEMATALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLSYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIR
                     VPLIQGFNADETSVKAITDFAADELHVSEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            10470..12902
                     /locus_tag="LSX49_003326"
     CDS             10470..12902
                     /locus_tag="LSX49_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBL7169700.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMAATETRESRRDELLTIAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            13048..13863
                     /gene="ybiV"
                     /locus_tag="LSX49_003327"
     CDS             13048..13863
                     /gene="ybiV"
                     /locus_tag="LSX49_003327"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HBL7169701.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIEFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHITLDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMSNAAENIKQIARYATDDNNHEGALNVIQAVLENKPPFNL"
     gene            complement(14063..15655)
                     /locus_tag="LSX49_003328"
     CDS             complement(14063..15655)
                     /locus_tag="LSX49_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HBL7169702.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIE"
     gene            15874..16794
                     /gene="ldtB"
                     /locus_tag="LSX49_003329"
     CDS             15874..16794
                     /gene="ldtB"
                     /locus_tag="LSX49_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HBL7169703.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            complement(16852..17970)
                     /locus_tag="LSX49_003330"
     CDS             complement(16852..17970)
                     /locus_tag="LSX49_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000056422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HBL7169704.1"
                     /translation="MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKALQYHTGGQTPEWKPRLVWSCLGLYIVFLTALE
                     LKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPVLQGVLSNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLAWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLLWAALVGYVLLVMIPAG"
     gene            complement(17967..18434)
                     /gene="mntR"
                     /locus_tag="LSX49_003331"
     CDS             complement(17967..18434)
                     /gene="mntR"
                     /locus_tag="LSX49_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HBL7169705.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            18620..18748
                     /gene="mntS"
                     /locus_tag="LSX49_003332"
     CDS             18620..18748
                     /gene="mntS"
                     /locus_tag="LSX49_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HBL7169706.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            19020..20603
                     /gene="opgE"
                     /locus_tag="LSX49_003333"
     CDS             19020..20603
                     /gene="opgE"
                     /locus_tag="LSX49_003333"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HBL7169707.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGISSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYLVGIFIFALGVIAIRRKKESEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(20652..21167)
                     /gene="ompX"
                     /locus_tag="LSX49_003334"
     CDS             complement(20652..21167)
                     /gene="ompX"
                     /locus_tag="LSX49_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HBL7169708.1"
                     /translation="MKKIACVSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(21220..21285)
                     /locus_tag="LSX49_003335"
     CDS             complement(21220..21285)
                     /locus_tag="LSX49_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169709.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            21520..>22359
                     /gene="rhtA"
                     /locus_tag="LSX49_003336"
     CDS             21520..>22359
                     /gene="rhtA"
                     /locus_tag="LSX49_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HBL7169710.1"
                     /translation="MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGST"
BASE COUNT         5485 a         6116 c         5504 g         5254 t
ORIGIN      
        1 tgatagttaa tgatgaaaaa aagaccaata aatgacaatg ctgccaataa aaataaaatt
       61 atcagcctta tctttatctt ttcgtataaa ctcagcatgt taatacattt aaaaaaataa
      121 ctgtctgaac gctgtgccgc tgcaaaatag tcccttgctg cggcttttta accaaattac
      181 ccgattctac aaaatcagca gaaagttaca acacttgctt agggcaataa tttcctgtga
      241 ggtgattacc ctttcaagca atattcaaac gtaactatcc tttaattttc ggatccagcg
      301 catcgcgtaa accatcgccc aacaaattga acgccagtac ggtcagaaaa atagccaggg
      361 ccggaaatac agcgacatgc ggcgcgataa ccatatccgc tcgtgcctca ttgagcattg
      421 caccccactc tggtgtcggc ggctgcgcac cgaggccgag aaatgacagg ctggcggcag
      481 agataatcga ggtgccaatg cgcatggtga aaaacaccac gatagaagag acggtcccag
      541 gcaagatatg acgcaacaaa atggtcatat cgctggcacc aatactgcgt gctgactcga
      601 taaaggtttg ctgtttcaac accagcgtgt tgccgcgcac cagccgggca aacgcgggga
      661 tggaaaaaat ggcgactgcg ataatcacgt tagcaatgcc gcttcccaac accgcaacaa
      721 cagcgatcgc cagtaaaata cccgggaagg caaacagcac atcgcaaatg cgcatgatca
      781 gccgatccca ccagccttca taatatccag ccagcaagcc cagcaacgtc ccgatcgccg
      841 caccgataaa cacggcaaac acgcccgccg ccagcgagat ttgcgcacca accaggacac
      901 ggctgaaaat gtcgcgcccc agtgaatcga caccaaacca gtgctgcaaa gaaggtccgt
      961 tattcagatt gtcataatca aaataatttt cggcgtcata gggagcgatc cagcgtgcaa
     1021 aaatggccac cacaatcaat aaaataacga acaatgcggc ggtcatcgcc atatgctgac
     1081 ggcgaaatcg tcgccagaat tcatgccacg gtgtacgtac ctggtcaggt ttgaccagtg
     1141 gcatggcgtt taacaccgcc tgacgtcgcc agttaaatag tcgcatcctt acttgtacct
     1201 gatagccggg ttaatggcgg cgtaaagcac atccaccact aagttgataa gaataaattc
     1261 cagcgagaaa agcagaattt ccgcctgaat cactgggtaa tcgcgcattt ctacggagtc
     1321 aacgagtaag cgtccaagtc cgggccagtt gaaaactttc tccaccacga tggaaccacc
     1381 gagcaagaag ccaaactgta agcccatcat ggtcactacc gggatcatcg cgttgcgtag
     1441 cccgtgtttg aggacaaccc aggtttcgct cacccctttc gccctcgcgg tacgcatata
     1501 atcttcgctt aaaacgtcga caaacgacgc gcgggtaaag cgcgccatca cggcggccac
     1561 tgccgcgccg agcgtcaggg agggtaaaat gtagtgctgc caactgtctg ctcccacggt
     1621 aggcagccag cccagttcaa cggagaatac ctgaattaaa agtatcccca gagcaaatgc
     1681 cggaaacgag atccccgaca ccgcaatggt catactcaat cgatccggcc aacggttacg
     1741 ccagacggcg gcgataattc ccgccgccat accaaatatc accgcccaga ccatactggt
     1801 tatggtcagc cagagcgttg gcataaagcg gctggcaatc tcatcggcaa ccggacgacg
     1861 cgacaccatc gacaggccaa aatccccctg cacagcattg ctgatatagt gccagaactg
     1921 gtgatacagc ggctgatcca accccaactg ctgacgcacc agttctataa cctgcgcatc
     1981 agcttcgggc ccggcaatca atcgcgccgg atcgccgggc agcatatgga caaataaaaa
     2041 caccagcacc gagacgataa acagcgtcgg aatcaacccc agtaagcgtt tgataacgta
     2101 attaagcatt ccactccctg cgttgcttat tgcaaatccg cgtcttcaaa gctgaagccg
     2161 gtgtctggca tgatccaaaa accggtcagg tttttactgt gtgccgacac cagtttttct
     2221 accaccagcg ggatccacgg cgactcttgc cagatgatat cctgcgccgc cttatacaag
     2281 cgggtctttt ccgccggatc attagttttc agtgcctgag ccaggaagtc atccacctgt
     2341 ttattgctgt aaaacgcggt attaaacagc gttggtggcc agttctgcga ggcaaacagc
     2401 ggcgatagag cccagtcggc ttcgccggtt gaagccgacc agccagtgta gaacatccgc
     2461 acgcagctct ctttttgccc tttaccttca acttctgccg cccgctgtcc ggcatccatc
     2521 gcagtcacct gggctttaat cccaacctgc gctaactgct gctgggtaaa ttgcagcact
     2581 ttctgcgcgg tgctgtggtt atgtgacgac cacagcgtgg tactgaaacc gttgggatat
     2641 cccgcctctt tcagtaattc gcgcgctttc actggatcgt aaggccacgg tttataactt
     2701 tgcgcgtagg cgatactcgg cggtaccaca ccagtagctg gcgttgcata gcccgcgaag
     2761 gccactttca ccagcgccgg gcggttaatg gcgtaattca gcgcctcacg gaccttcggg
     2821 ttatcgaacg gcttttgcgt cacgttcata ctgatataac gctgcataat tgacggactg
     2881 gccatcaact cgatattttt gtttttctcc agcagtgcgg cctgctcgta gggaatgggg
     2941 aaagcaaact gcgcttcacc ggtttgcagc attgccgcgc gggtgttgtt atccgccacc
     3001 ggacgccagg ttatgctgtc cagtttgggc aatcctggct gccagtaacc cgcgaatttt
     3061 ttcaccttca caaaatcggt ctgattccag gtatccagtt catacggccc ggttcccacc
     3121 ggatgaaaac caatctcctt gccatatttt tccagcgctg ccggtgatat catcgcggtc
     3181 gccggatggg caagaatatt aataaacgct gagaatggct gtttgagggt aatctttacc
     3241 gttgtcggat cgatcgcttc cgttttggcg atattcttat acaggttata gcgtttaaga
     3301 tgattcgccg gatcgctggc ccggtccaga ttcgctttca ccgccgctgc gttgaaatcg
     3361 gtgccatcct ggaatttaat gccttcccgc aatttcacgg tgtaagtaag gccgtcatcg
     3421 gaaacggtgt aactctccgc cagcacgttt ttcagtttca tctctttatc cagaccgaac
     3481 agcccctggt aaaacgattt cgctacggcc tgagataacg tgtcatttgc gtcatacgga
     3541 tcgagcgtgg tgaagttcga tcccaccgcc accaccacct ctttggcagc gaatgcacaa
     3601 gatgccatca acgctgtcgc aatgcccagc gccactaacc cactacggtg tacagctctt
     3661 gccattttat tctccgcctg aatgttatct acgcatgaat gcgtattctg attgtggttg
     3721 tgcgacgtaa tgccccggcc cgacgcattg caacgagacg gctgcaacct cttcgccacg
     3781 cagatgaata ttgctgggaa gatcgtccga cagcagtaca cgctgcggtc gttgtcggga
     3841 cggttcagcg accggaactg ccgccagtaa tttacgcgta taaggatgct gcggattttc
     3901 aaagaccgcg cgccgtggac caatttcaac aatttgcccg agatacatca ccgccacacg
     3961 atgactaatc cgctcaacca cggccatatc gtgggagata aacagatacg caatgccgaa
     4021 atcacgctgg agatcgagca acaagttgat aatctgcccg cgaatagaaa catccagcgc
     4081 cgagacggct tcgtcggcaa tgatcacttt tggattcaat gccaacgcgc gagcaatgca
     4141 gatgcgctgg cgctgaccgc cggaaaactc atgtgggtaa cgccaggcat gttccggtaa
     4201 caggcccacg cgctccagca accacgcaac gcgtgcagcc gcttctttac ctggcaataa
     4261 accgtgtacg cgcagcggtt cgagaatcga atcaccgata gtctgacgtg ggtccagcga
     4321 agcgtaaggg tcctgaaaaa taaactgaat atcgcggcgc aatgcctgaa gtttaccggg
     4381 tgacaaggta tcgattcgct gaccgttaaa gataatttcg ccgccctgcg attcgaccag
     4441 gcgcaacaac gcccgcccgg tagtggattt accgctgcca gactcgccca ccagcgatag
     4501 cgtttcgcca ggccagagat caaaactgac tttctcaacg gcatgcactt cccgcgttac
     4561 gcgattcaac aaaccgctgc gcaaagggaa acgggtgacc agattacgca cccgtaaaac
     4621 aggttcgcca tccaccaccg ttttctgctc gatggatgac tcctgtttcg ctggatgttc
     4681 aagcgatatc aatgggaaac gtcggggata atctaaccct ttcatcgcac caagttgcgg
     4741 aacagcagct aacagcgcac gggtataagg atgttgcggt gcatgaaaaa tctgttcgac
     4801 gctacccgtt tccaccgcct cgccctgata catcaccagt acccgatcgg caatctctgc
     4861 caccacaccc atatcgtgag tgataaagat aacgcccatc gacatctctt tttgcaatac
     4921 tttgattaat tgcaggatct gcgcctgaat agtgacatcc agcgcggtgg ttggctcatc
     4981 ggcaatcagc accgccgggc ggcatgacag cgccatcgca atcatcactc gctggcgcat
     5041 cccgccagag agttgatgcg gataacgtga aagaatggtt tgtgcctccg gaatgcgtac
     5101 ctgatccagc atccgcttcg cctcgaccat cgcttcttca cgactggcgt tctgatgcag
     5161 acgaatagat tcagcaatct gttcacccac agtaaatacc gggttcagcg atgtcatcgg
     5221 ctcctgaaat atcatcgcca tatccgcacc gcgcacatgg cgcatttgtg cagcgctctg
     5281 ctcgctaagt tcaattactt cgcgactgcg ccgctgcaac agcattttat cgcactgcac
     5341 taaaccgccc gcctgttcca acaggcgcat caatgccagc gcagtcactg acttaccgga
     5401 gccggattcg ccaacaattg ccagcgtctc accacgttgc aggctaaaag agagattgcg
     5461 gaccgcagct attttctgct gctcctgcat aaaggcaata ttcagatttt caaccgccag
     5521 cacatcaccg gcatcaagtt catcactgtg tggcaacggt gtcccctttt tcacggtaga
     5581 taccggtggt tggcgtatcg cctgcgtagc cccaggcgcg atacattcct tcggtgttaa
     5641 acggtagcgc gacattccct tcatggtcga tagcgattaa gccaccgcta ccgccaagcg
     5701 cagggagttt ttccattact acccgctcgc aggcttccgc gagacttaat ccgccgtaat
     5761 ccattaacgc ggcgatatca tatgccgcca gcgcgcggat gaagacttcg cccgtaccgg
     5821 tacaggaaac cgccacactg gcgttattgg catagcatcc ggcccccact aagggactat
     5881 cgccaactcg tccgggtaat ttattggtca ttccgcccgt ggacgtggct gccgccagat
     5941 tgccgtctaa atccaacgcc acggccccta cggtgcccat tttctgtttt tcatccagtg
     6001 gcgcaccgct atggtcgagg actgttgccc cttcctcgcg cgctgccatt agttgttcat
     6061 aacgcaaagg tgtggagaaa atctccggcg agacgcgctc catgccatga gcaaacgcaa
     6121 aattttctgc cccttcgcca atcatcatca catgcgggct ttgctccatc accagccggg
     6181 cggcaagaac cggattacgc agatgactaa cgcccgccac cgcaccggct ttcagggtgt
     6241 taccatccat cagacaggcg tccagttcat gggtttcatc acgcgtaaag acagcgccaa
     6301 ttccggcgtt aaacagtgga cactcttcca gcagacgcac cgcttccgtc accacatcca
     6361 gcgcactttc gcccgctacc agcattttct gcccggtttc aacaatggca gacaacgcct
     6421 cgatgtagcg taattcctgt tgcagactca tctgcgcgcg gctaattgca cctgcgccac
     6481 catgaattgc aatgactgct ttgcccatag tattcgtcca ttaagagtgg ctcgccactt
     6541 ttgctataaa tatcagaatt tttatgaatg actcattcaa tttttgaata tagaaagatg
     6601 gatatggcat gtaaaggcag gagccagcgc tacgcccgag gtggcataca gtctgtggcg
     6661 tttttctgac ataataggca aattcgattt tgcctccgca ggagtgtttt catggaattt
     6721 accaccggat tgatgtcgct cgacaccgcg cttaatgaga tgctttctcg cgttacccca
     6781 ctgaccgccc aggaaacgct gccactggtt cagtgttttg gccgtattct ggcgagcgat
     6841 gtcgtttcgc cactggatgt cccggggttt gataactccg ctatggacgg ctacgcggtg
     6901 cgtttagccg atattgcctc cgggcaaccg ctgcccgttg ctggtaaatc ctttgccggt
     6961 cagccgtacc atggtgaatg gcctgcgggt acctgcattc gtattatgac cggtgcgccg
     7021 gtgccggaag gctgcgaagc ggtggtgatg caggagcaga ctgaacaaac ggacaatggc
     7081 gtgcgtttta ctgctgaagc gcgtagcggg caaaatattc gccgtcgcgg tgaagatatc
     7141 tctgcaggtg cggttgtttt cccggcgggg actcgcctga ctaccgctga actgccagtg
     7201 attgcttcgc tagggattgc cgaagttccg gtgattcgta aagtgcgtgt agcgcttttt
     7261 tctaccggtg atgaactcca gttgcccggt cagccgctgg gcgacggcca aatctacgat
     7321 accaaccgtc tcgccgtaca cctgatgtta gaacagttgg gatgcgaggt aatcaactta
     7381 gggattatcc gcgacgatcc ccatgccctg cgcgccgcat ttattgaagc cgacagccag
     7441 gcggatgtgg tgatcagttc cggcggtgtt tcagtgggtg aagcggatta caccaaaacg
     7501 attcttgaag agctggggga gatcgccttc tggaaactgg cgattaaacc gggtaaaccg
     7561 ttcgcgttcg gtaaactttc taatagttgg ttctgcggcc tgccgggcaa cccggtttca
     7621 gcgacgctga ccttctatca actggtacag cctttgctgg caaaactaag cggcaatacc
     7681 gccagcggcc tgcccgcgcg ccagcgtgta cgcacggcat cgcctctgaa gaaatcgcca
     7741 ggacgccttg atttccagcg cggcgtgctg caacgcaacg ccgatggcga actggaagtg
     7801 acgaccaccg gacatcaggg ttcacatata tttagctcct ttagcctcgg caactgcttt
     7861 atcgtgctgg aacgcgatcg cggcaatgtg gaagtgggcg aatgggtgga agtagaaccg
     7921 tttaacgcgt tgttcggagg cctgtaatgg cggaactcag cgatcaggag atgctgcgct
     7981 acaaccggca aatcattctg cgcggttttg attttgacgg tcaggaagca ttgaaagatt
     8041 ctcgcgtgct ggtcgtcggc cttggtggac tcggctgcgc agcttcgcag tatctggcaa
     8101 gcgccggtgt cggcaacctg acgctgctcg acttcgacac ggtttcgctc tccaatctgc
     8161 aacgccagac gctgcacagt gatgccacgg tcgggcaacc aaaggtggaa tccgcccgtg
     8221 acgccctgac gcggatcaac ccacatatcg cgattacgcc agtcaatgcg ctgcttgatg
     8281 acgctgaact tgctgcgatg attgcaaaac acgatctggt gctcgactgt acggataacg
     8341 ttgcagtacg taatcaactg aacgcaggct gttttgccgc gaaggtgccg ctggtttccg
     8401 gcgcggcaat tcgtatggaa gggcaaatca cggtcttcac ttatcaggac ggcgaaccgt
     8461 gctatcgctg ccttagccgt ttgtttggcg agaacgcgtt aacctgcgta gaagcaggcg
     8521 tgatggcacc gttaatcggc gtaattggtt cgttgcaggc aatggaagcg atcaaactgc
     8581 tggcaggtta tggcaaacca gccagcggga aaatcgtgat gtacgatgcg atgacctgtc
     8641 agtttcgcga aatgaaactg atgcgcaatc cggggtgtga ggtgtgcggg cagtaactgc
     8701 cacctccagg ccagataaga cgcggcactc cgccacgtca tcagcaattt atgaggatgc
     8761 agaacgtccg gttaaatcga cgttctgcca aacgctccct gccagtcctg ctcaaacttc
     8821 gccacagcgg catcaaccgc cggatagcta atcatctgtt gtgccacatc cagtggcaga
     8881 gtaattgatt cacaccctgc cagtaagcag tccagcgcct gacgcggggt tttgaaactc
     8941 gcggctaaca ctttcgcctg cggcgcatgc attttcaata actggtgtaa gtcggtcaca
     9001 gtctgaatac cgctaccgcc ctgagcatca atacgattaa cgtaaggcgc aacatattcc
     9061 gcacctgcca gcgccgacag tagcccttgt gctgcgccat ataccgcggt tcccagcgtc
     9121 ggaatccctt ccgcttttaa catcttaata gctgccagcc cctctgcggt caccggaact
     9181 ttcaccacga tatccgcaat aatagaacgc aatttacgtg cgtcattcac catcccttca
     9241 gcagtggtag ccattacctg ggcaaacaga cgcccctgac cgcccatcgc ctcgtgaagt
     9301 tgcggaagca caacctccag cggtttttta cccactgcga taatgcttgg gttagtggtt
     9361 acacccgcca gcggaaaaat acgtgacagc gccttcaccg caacaacgtc tgaagtatcc
     9421 agatacagtt ccataaccat cctcaaaatg tactttttgt ctgaatgtag actatcacgg
     9481 gaaaactctc tgaacagttg acgcacatca atccaacttt cattcgaaag tattttaatg
     9541 tttgaacgaa acagagaggc aactatgatt ttcaatattc aacgctactc gacccatgat
     9601 ggccccggta tccgcacggt cgtatttctt aaaggctgtt cgctgggctg ccgctggtgt
     9661 cagaacccgg aaagccgcgc ccgcacgcag gatctgctgt atgacccacg actctgtctg
     9721 gaaggctgtg agctgtgcgc taagaccgca ccggaagtga ttgagcgcgc gttgaatggt
     9781 ttgcttattc atcgggaaaa gttaaccccg gagcatttta cggcgctaac cgactgctgc
     9841 ccgacacagg cgttaaccgt gtgtggtgaa gtgaaaagcg ttgaggagat catggcaacc
     9901 gttttgcgcg ataaaccgtt ttacgatcgc agcggcggcg gcttaacact ttctggcgga
     9961 gaacccttta tgcagccgga aatggcgaca gcgctactgc aagccagcca cgaagccggt
    10021 attcatactg cggtagaaac ctgtctgcat gtgccgtgga aatatatcgc cccttctctg
    10081 tcctatattg atctgtttct tgccgattta aaacacgttg ccgacgcgcc gtttaaacag
    10141 tggaccgacg gtaacgccgc cagggtgctg gataatctga aaaaactcgc cgcagcgggc
    10201 aaaaaaatca ttatccgcgt gccactgatt cagggcttta atgccgacga aacctctgtg
    10261 aaagccatta ccgattttgc cgccgacgag ctgcacgtta gcgaaattca tttcctgccc
    10321 taccacacgc tgggcatcaa caaatatcac ttacttaatc tgccctatga cgccccggaa
    10381 aaaccgcttg atgcgccaga actgctcgac tttgcccagc agtatgcctg ccagaaaggg
    10441 ttaaccgcga ccttacgagg ataacaacca tgaccacact gaaactggac acgctcagcg
    10501 atcgcattaa agcgcacaaa aatgcgctgg tgcatattgt gaaaccgccg gtctgtaccg
    10561 agcgcgcgca gcactatacc gagatgtatc aacaacatct cgataagccg atcccggtac
    10621 gtcgcgcgct ggcactggcg catcacctgg cgaatcgcac catctggatc aaacatgatg
    10681 aattgatcat tggcaaccag gcaagcgaag ttcgcgccgc gccgatcttc ccggaatata
    10741 ccgtctcctg gatcgaaaaa gagattgatg atctggcaga tcgtcccggt gctggttttg
    10801 cggtgagtga agagaacaaa cgcgttctgc atgaagtgtg cccgtggtgg cgcggtcaga
    10861 ccgtacagga tcgctgctac ggcatgttta ccgatgagca aaaaggtctg ctggcgaccg
    10921 gcatcattaa agcggagggc aatatgacct ccggcgatgc gcacctggcg gtcaatttcc
    10981 cgctactgct ggaaaaaggt cttgatggtc tgcgtgagaa agtggcggaa cgtcgctcgc
    11041 gcatcaatct gacggttctg gaagatctgc acggcgagca attcctgaaa gcgattgata
    11101 tcgtgctggt ggcagtcagt gaacacattg aacgtttcgc tgccctggcg cgtgaaatgg
    11161 ccgcgaccga aacccgcgaa agccgtcgcg atgaactgct gacgatagca gaaaactgcg
    11221 atcttatcgc ccaccagccg ccgcagactt tctggcaggc gctgcaactg tgttacttca
    11281 tccagttgat tttgcagatt gaatctaacg gtcactcggt atcgtttggt cgtatggacc
    11341 agtatctcta tccatactat cgccgtgacg ttgaactgaa ccagacactg gatcgcgaac
    11401 acgccatcga gatgctgcat agctgctggt tgaaattgct ggaagtgaac aaaatccgct
    11461 ccggctcaca ctcaaaagcc tctgcgggaa gtccgctgta tcagaacgtc accattggcg
    11521 ggcaaaatct ggttgatggt caaccgatgg acgcggtaaa tccactctct tatgcgatcc
    11581 tcgaatcttg cggtcgcctg cgttcgactc agcctaacct cagcgtgcgt taccatgcgg
    11641 gtatgagtaa cgatttcctc gacgcctgtg ttcaggtgat ccgctgcggc ttcgggatgc
    11701 cggcgttcaa caacgacgaa atcgtcatcc cggaatttat taaactcggt attgaaccgc
    11761 aggacgctta cgactacgca gcaattggtt gtatcgaaac cgccgtcggt ggcaaatggg
    11821 gctatcgctg taccggcatg agctttatca acttcgcccg cgtgatgctg gcggcgctgg
    11881 aaggcggtcg tgatgccacc agcggcaaag tgttcctgcc acaagaaaaa gcgttgtcag
    11941 cgggtaactt caacaacttc gatgaagtaa tggacgcatg ggatacgcaa atccgttact
    12001 acacgcgtaa atcaatcgaa atcgaatatg tcgtcgacac catgctggaa gagaacgtac
    12061 acgatattct ctgctcggcg ctggtcgatg actgtattga gcgagcgaaa agtattaagc
    12121 aaggcggcgc gaaatatgac tgggtttctg gcctgcaggt cggcattgct aacctcggca
    12181 acagcctggc ggcagtgaag aaactggtat ttgaacaggg cgcgattggt cagcaacagc
    12241 tggctgccgc actggcggat gacttcgacg gtctgactca cgagcagctg cgtcagcggc
    12301 tgattaacgg tgcgcctaag tacggcaacg acgatgatac tgtcgatacg ctgctggctc
    12361 gcgcttatca gacctatatc gacgaactaa aacagtacca taacccacgc tacggtcgtg
    12421 gtccggttgg cggcaactat tacgcgggta cgtcgtctat ctccgctaac gtaccctttg
    12481 gcgcgcagac tatggcaaca ccggacgggc gtaaagcgca taccccgctg gcagaaggcg
    12541 ctagtccggc ctccggtact gaccatctcg gcccaacggc ggtcattggc tcagtaggta
    12601 aactgcctac ggccgcgatt ctcggcggcg tgctgctcaa ccagaaactg aatccagcaa
    12661 cgctggagaa cgaatctgac aagcagaaac tgatgatcct gctgcgcacc ttctttgaag
    12721 tgcataaagg ctggcatatt cagtacaaca tcgtttcccg cgagacgctg ctggaggcga
    12781 aaaaacatcc ggatcagtat cgcgatctgg tagtgcgcgt cgcgggctat tccgccttct
    12841 tcaccgcgct ctctccagac gctcaggacg atatcatcgc ccgtactgaa catatgctgt
    12901 aatcttctca gcccggcggc ggcgtcgccg ggctaaatca ttcacatcat caatttcagc
    12961 ctcgctttca ttcgaaatat aatttgtgct ctgcgtcaca ttgttattac actgttacgg
    13021 tttcattttc gagccaggag cacacctatg agcgtaaaag ttatcgtcac agacatggac
    13081 ggtacttttc ttaacgacgc caaaacgtac aaccaaccac gttttatggc gcaatatcag
    13141 gaactgaaaa agcgcggcat tgagttcgtt gtcgccagcg gtaatcagta ttaccagctt
    13201 atttcgttct ttcctgagct aaaggatgag atctcttttg tcgcggaaaa cggcgcactg
    13261 gtttacgaac atggcaagca gttgttccac ggcgaactga cccgacatga atcgcggatt
    13321 gttattggcg agttgctaaa agataagcaa ctcaattttg tcgcctgcgg tctgcaaagt
    13381 gcatatgtca gcgaaaatgc ccccgaagca ttcgtcgcac tgatggcaaa acactaccat
    13441 cgcctgaaac ctgtaaaaga ttatcaggag attgacgacg tactgttcaa gttttcgctc
    13501 aacctgccgg atgaacaaat cccgttagtg atcgacaaac tgcacataac gctggatggc
    13561 attatgaaac ccgtcaccag tggttttggc tttatcgact tgattattcc cggtctacat
    13621 aaagcaaacg gtatttcgcg gttactgaaa cgctgggatc tgtcaccgca aaatgtggta
    13681 gcgattggcg acagcggtaa cgatgcggag atgctgaaaa tggcgcgtta ttcctttgcg
    13741 atgagcaatg ctgcggaaaa cattaaacaa atcgcccgtt acgctaccga tgataataat
    13801 catgaaggcg cgctgaatgt gattcaggcg gtgctggaaa ataaaccgcc gtttaatctt
    13861 tgattatcac caattcagtt tattgagaaa gtgcatgtca ttataccgga tacggcgtga
    13921 ccgccttatt tggcatacaa aatcatgaaa attcaatata ttgcgataca ctaccaggcc
    13981 tgataagcgt agcgcaccag gcaatcttgc gtttgtcatc agtttcagta gccctgacca
    14041 tatcagggct actgataata acttactcga tccctttact acgcaggtaa tcttcgtaat
    14101 taccgctaaa gtcgatcacg cgttccgggg tgatttccag aatacgggtc gccagggagc
    14161 ttacaaactc acggtcgtga gaaacaaaga tcagcgtgcc ctgatacagt tccagcgcca
    14221 tgttcagcga ctcaatggat tccatatcca ggtggttggt cggttcgtcc atgatcagaa
    14281 tgttcggctt ctgcatcatt aacttaccaa acagcatccg ccctttttcc ccaccggaaa
    14341 gcactttagc tggctttttg atgtcgtcct ggctgaacag caaacgaccg agaatactgc
    14401 gcaccgcctg ctcgtcatcg ccttcctgct tccactgact catccattcg aacacggtca
    14461 gatcattttc aaactcatat tcgtggtcct gagcgtagta accaatgcgc gcgttttcag
    14521 accattttac ggtgccgctg tccggttgca gatcgcccac cagcgttttc agcagcgttg
    14581 atttaccgac gccgttggta cccagtaccg ccagtttttc acccacttcc agcagcaggt
    14641 tgagattttt aaacagtgga ccgttatcaa accctttagt cagaccttcc acttctagcg
    14701 cgttacggaa cagtttctta tcctgttcaa aacggatgaa cgggttctga cggctggaag
    14761 ctttcacctc ttccagtttg attttatcaa tctggcgcgc gcgcgaagtt gcctggcgag
    14821 atttcgaggc gttggcgcta aagcggctaa cgaaagattg caactcagca atctgcgctt
    14881 tcttcttcgc gttatcagcc agcagacgtt cacgcgcctg agtcgccgcc gtcatgtact
    14941 catcgtagtt gcccggataa acgcgcagct cgccgtaatc cagatccgcc atgtgggtac
    15001 aaaccatgtt aaggaagtga cggtcgtgcg agatgatgat catggtgctg tcacgctcgt
    15061 tcagcacctg ttccagccag cgaatggtgt cgatatcgag gttgttggtc ggttcgtcga
    15121 gcaggagaat gtcgggatca gcaaacagcg cctgagccag cagcacacgc agcttccagc
    15181 caggagcaac ttcactcatc gggccgtagt gctgttccac tggaattccc acgccaagca
    15241 acagttcacc agcgcgagct tccgcagagt aaccgtccat ttcgccgtat ttcacttcca
    15301 gatcggccac tttatagccg tcttcttcac tcatttccgg caaagcatag atgcggtcac
    15361 gctcctgctt cacttcccac aactctttat gccccatgat caccgtatcc agcacagtga
    15421 actcttcaaa ggcaaactga tcctgacgca gcttaccaat gcgttcgttg ggatcgaggg
    15481 aaacgttacc caacgtcggc tctaagtcgc cgccgaggat cttcataaag gtggatttac
    15541 cactaccgtt cgcgccaatc aggccgtaac ggttgccgcc gccgaatttg acggaaatgt
    15601 tttcaaacaa cggcttactg ccgaactgca tggtgacgtt actggaaact aacacaggcg
    15661 tatcctgaaa agagatatga caaaccgcgc attatgccat aagtctgaaa gaagatcctg
    15721 ctcctcgctt aaggtctaca ctcaagccaa aggcaaaaaa tgtgatttcg tacacatctg
    15781 atttcactgt gagctggaat gaacttataa tgcgcttcca gtactctaat attctcaacc
    15841 caatggcctg ccaggcacaa aatctcgctt aacatgaata tgaaattgaa aacattattc
    15901 gcagcggcct tcgctgttgt cggcttttgc agtaccgcct ctgcggtaac ttatcctctg
    15961 ccaaccgacg ggagtcgcct ggttggtcag aatcaggtga tcaccattcc tgaaggtaac
    16021 actcagccgc tggagtattt tgccgccgag taccagatgg gactttccaa tatgatggaa
    16081 gcgaacccgg gtgtggatac cttcctgccg aaaggcggta ctgtactgaa cattccgcag
    16141 cagctgatcc tgccggatac cgttcatgaa ggcatcgtca ttaacagtgc agagatgcgt
    16201 ctgtattact atccgaaagg gaccaacacc gttatcgtgc tgccgatcgg cattggtcag
    16261 ttaggcaaag acacgcctat caactggacc accaaagttg agcgtaaaaa agcaggcccg
    16321 acctggacgc cgaccgctaa aatgcacgca gagtaccgcg ctgcgggcga accgcttccg
    16381 gcggtcgttc cggctggtcc ggataacccg atggggctgt atgcactcta catcggtcgc
    16441 ctgtacgcta tccatggcac caacgccaac ttcggtatcg gcctgcgtgt aagtcatggt
    16501 tgtgtgcgtc tgcgtaacga agacatcaaa ttcctgttcg agaaagtacc ggtcggtacc
    16561 cgcgtacagt ttattgatga gccggtaaaa gcgaccaccg agccagacgg cagccgttat
    16621 attgaagtcc ataacccgct gtctaccacc gaagcccagt ttgaaggtca ggaaattgtg
    16681 ccaattaccc tgacgaagag cgtgcagaca gtgaccggtc agccagatgt tgaccaggtt
    16741 gttctggatg aagcgatcaa aaatcgttcc gggatgccgg ttcgtctgaa ttaatcttca
    16801 aaacgtaaag caaaggcgga ctcataatcc gcctttttaa tttgacagac cttatcccgc
    16861 cgggatcata accaacaaaa catatcccac cagcgccgcc cacaacagca tcggtatcga
    16921 ataaagatga aaacgccacc agatacggcg atcgttcgcc atccgtaacg caatcaaatt
    16981 tgccagcgat ccgggtaata aaccaaagcc acctacgttt accgcccatg ccagtaataa
    17041 agacggtggc acataattga gcagcaaaat ggtactcggc acgttactga tcacctgcga
    17101 taaaccgatc gccgttagcc ataatccggg ttcggataaa tgactcacgt tacttaacac
    17161 cccctgcaaa actggcagtt gggttagtaa atggacgtcg ataaacatcg ccataaacac
    17221 cagcagcagc gtccagtcca cactgagcac cacgcgacgc gccagcagcg caaagcccgc
    17281 cgccacaatc accagtcccc acagctcttg ttttaactcc agcgccgtca gaaagacgat
    17341 atacagcccc agacaactcc acaccagccg cggtttccac tccggcgttt gccctcctgt
    17401 atggtactgc agcgcctttc cagggaaaca acaccagcac aacagcagga gtgtcagcat
    17461 cattgcgcca gccagcggtg ccatttgggc aataaatccg gcaaacgaaa gaccagaacg
    17521 tccccagata agaatatttt gcgggttgcc aattggcgtc agtagcgaac cagcattgac
    17581 tgccagcgcc tcaaaaataa tcagccgatt aaccgggatc tcacacagtc tttttagcgt
    17641 gatagtcagc ggaacaacta taaacagcgc gacatcgttg gtcagaaagg tagaaagcag
    17701 cgccgccgcc agtaccataa acatcgccag ccgacgctcc gtagcaaaac ggcgcaccat
    17761 tttgcgcccc agcacatcaa aataaccgct taactcgaca cctttagtca gcagcatcag
    17821 gccgcttaag gtgatgatgg tgtgccagtc gatagcagca ggccaggatt tcggtgcaaa
    17881 gggaacgaaa aaacttaatc cgatgccaac aagaattaat aactgaaaaa aacgatcgcc
    17941 ttgcagcgtg cgtaaaaaag gcaggctcat ttggcaccgt gtttctgggt aaacaaacga
    18001 aaggcatcca gcgtctcttc actaacatgg tgctccatac cttccgcgtc gcgacgggcg
    18061 atttccggac tgacgcccaa caccaacaag aaattttcga ctatctgatg tcgctcgcgg
    18121 ctttcctgcg ccagcttctc tccttctgcc gttaaaaaca cgccacgcca ggggatcatt
    18181 tcaatcagcc ccatggttgc cagtcgctta agcattttag ccaccgtcgg ttgcgaaacc
    18241 cccagacgag cagccatgtc tacctgacga gcttccccca cttccctgat caagtcagaa
    18301 atcagctcaa cataatcatc aataagctcg cgccgatgcg cctctctgac ctggcggaac
    18361 ccttcaacgt gctcttccac gttcactaac tgcgtcactt tttttgctgt tggcgtacct
    18421 gcgcgacgac tcattatgct tcctcattat ggtgacgcat acatagcgtt ctcatttcgt
    18481 gcgcacattg taaaccagag ttgcgaaggt acaaaaaatt aacgttttag caatagctat
    18541 ataatatagc ctgtgctata tctgtatgta atgcaatcat ccctcaagga tcgatgggat
    18601 tagcaagtca ggaggtctta tgaatgagtt caagaggtgt atgcgcgtgt ttagtcattc
    18661 tccctttaaa gtacggttaa tgctgctctc tatgttgtgc gatatggtca acaacaaacc
    18721 gcagcaggat aaaccttccg ataaatagcg gcgtcgcggt acgccgcttc actcctgctt
    18781 ttatgcaggc acaacgcgtt ttggtctgaa aaaccccact ttttgtcgga tttgcaatcc
    18841 ccttcgcaaa agatttgttc gtcggtagtt gacctgaaca gcagctcgct ctatcttctt
    18901 gcagccctgc gtatattgcg gctcgcggat gcggacccct ttcccctctt cacgcactct
    18961 tgcaggtatt gacccttgac gccagggtaa gcacatggcg tttgttacga tagtggcata
    19021 tgaatttaac cctcaaagaa tcgcttgtta cccgtagccg ggtatttagc ccgtggactg
    19081 cgttctactt tttacagtcg ctattaatta acctcggctt aggttacccc ttcagtttgc
    19141 tctacaccgc tgcgtttacg gctattttgc ttttgctatg gcgaacattg cctcgcgtac
    19201 aaaaagttct ggtcggtatc agttcgctgg tggcggcttg ttatttccct tttgctcagg
    19261 cctacggcgc gcctaacttc aatacattgc tggcattgca ctccaccaat atggaagagt
    19321 cgaccgaaat cctgacgatt tttccgtggt acagctacct ggtcggcata tttatttttg
    19381 cgctcggcgt aatagcaatc aggcgaaaaa aagagagtga aaaagcgcgc tggaatacct
    19441 tcgacagcct gtgcctggta ttcagtgtgg cgacattttt tgttgctccc gtgcaaaacc
    19501 tggcctgggg cggcgtattt aaactgaaag atactggcta tccggtattt cgttttgcta
    19561 aggatgtcat cgtcaataat aacgaggtga ttgaagagca agaacggatg gcaaaacttt
    19621 ccggaatgaa agatacctgg acggtcactg ccgttaagcc gaagtatcag acctatgtgg
    19681 tggtgatcgg agaaagcgcg cgtcgcgatg ccctcggtgc ctttggcggt cactgggaca
    19741 ataccccgtt tgccagcagc gttaacggtt tgatatttgc tgactacatt gccgccagtg
    19801 gctccacgca gaaatcgctt ggcttaacgc tcaatcgcgt tgtcgatggc aaaccacagt
    19861 ttcaggataa ctttgtcacc ctggcaaatc gcgcgggctt ccagacctgg tggttttcca
    19921 accagggtca aatcggcgaa tacgataccg ccatcgccag catcgccaaa cgagcagatg
    19981 aagtgtactt cctgaaagaa ggtaattttg aagcagataa aaacacgaaa gacgaagcgt
    20041 tactggatat gaccgctcaa gtgctggcgc aagagcactc gcaaccgcag ctgattgttc
    20101 tacatctgat gggctcgcat ccgcaggcct gcgaccggac acaaggaaaa tacgaaacct
    20161 ttgtgcaatc gaaagaaacg tcgtgctatc tctataccat gacgcaaaca gacgatttac
    20221 tgcgcaagct gtacgatcag ttacgcaaca gcggcagcag cttctcgctg gtttactttt
    20281 ctgaccacgg tctggccttt aaagagcgcg gcaaagacgt gcaatacctt gctcatgatg
    20341 ataagtatca gcaaaatttc caggtgcctt ttatggtcat ttccagcgac gataaagcgc
    20401 atcgggtgat taaagcccgc cgctcggcca atgacttctt aggctttttc tcgcagtgga
    20461 cgggaattaa agcgaaggaa ataaatatca aatacccgtt tatatctgaa aagaaagccg
    20521 ggccgatata catcaccaac ttccagttac agaaggtgga ttacaaccat ctcggaaccg
    20581 atattttcga cccgaaacct taaaacaaaa aaatccgccc cgagaggcgg atttttatat
    20641 caccgaagtg attagaagcg gtaaccaaca ccggcaatcc aggtgcctac gtcaacgcta
    20701 cgaatacggc tctgctcgta agagaagtcc agagcaacgt tttccatcgg gttgaactgc
    20761 agaccagcac cgtaggagaa accgtagtcg ctggtgtcgt gtttgtaggt cgggtattca
    20821 gtggtctgga atttaccata acccacaccc actacaccgt agatgcttgc ccagtcgtta
    20881 atgcggtaag ccggaccagc agtgatgccg tagtactggt ttttgttgta gtcaccagag
    20941 cttgcagtac ggcttttctc ggtgtaagtg aaagaaccga tcacacccag cgggctgttg
    21001 tcttcttcat agcggtattt caggttgaaa ccgcccattt tgttcatttg gccctgagcg
    21061 tcgctctgtg cgtaaccgcc agttacagta gaagtcgcag ctacggaagt acctgcggtg
    21121 aaagccagaa ctgcggccag tgctgaaaca catgcaattt ttttcataac cacctcaaat
    21181 gtgattcaaa taagtcctaa gttttaaata tatcaaaaat taatgggaaa ctcttcgcga
    21241 tttatgatgt ctaacgggcc atttcatgta acagaacgtt tccatacacc gctatccatc
    21301 taaatttaaa tcactttttc agagaactgc gtaagtatta cgcatatttt ccctgtcatt
    21361 catccagatt attcctaatc accagactaa tgattccatc aatcctggcg cattttagtc
    21421 aaaacggggg aaaatttttt caacaaatgc tcaaccagca ttgggtatat ccagtacact
    21481 ccacgcttta cttaggttta gatatttgtg ggagaaagga tgcctggttc attacgtaaa
    21541 atgccggtct ggttaccaat agtcatattg ctcgttgcca tggcgtctat tcagggtgga
    21601 gcctcgttag ctaagtcact ttttcctctg gtgggcgcac cgggtgtcac tgcgctgcgt
    21661 ctggcattag gcacgctgat cctcatcgcg ttctttaagc catggcgact gcgctttgcc
    21721 aaagagcaac gattaccgct gttgttttac ggcgtttcgc tgggtggaat gaattatctt
    21781 ttttatcttt ctattcagac ggtaccgctg ggtattgcgg tggcgctgga gttcaccgga
    21841 ccactggcgg tggcactgtt ctcttctcgt cgcccggtag atttcgtctg ggttgtgctg
    21901 gcggttcttg gtctgtggtt cctgctaccg ctggggcaag acgtttccca tgtcgattta
    21961 accggctgtg cgctggcact gggggccggg gcttgttggg ctatttacat tttaagtggg
    22021 caacgcgcag gagcggaaca tggccctgcg acggtggcaa ttggttcgtt gattgcagcg
    22081 ttaattttcg tcccaattgg agcgcttcag gctggtgaag cactctggca ctggtcggtt
    22141 attccattgg ggctggctgt cgctattctc tcgaccgctc tgccttattc gctggaaatg
    22201 attgccctca cccgtttgcc aacacgcaca tttggtacgc taatgagcat ggaaccggct
    22261 ctggctgccg tttccgggat gattttcctc ggagaaacac tgacccccat acagctgctg
    22321 gcgctcggcg ctatcatcgc cgcttcaatg ggttctacg
//
LOCUS       DAFGPF010000078        22289 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFGPF010000078 DAFGPF010000000
VERSION     DAFGPF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22289
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.078"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            24..1478
                     /locus_tag="LSX49_003337"
     CDS             24..1478
                     /locus_tag="LSX49_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HBL7169711.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGIGPIFDYIPGG
                     IQKAENSGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIPFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG"
     gene            1538..2899
                     /gene="allB"
                     /locus_tag="LSX49_003338"
     CDS             1538..2899
                     /gene="allB"
                     /locus_tag="LSX49_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HBL7169712.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGG
                     IAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQ
                     PNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILK
                     HQQ"
     gene            2955..4256
                     /locus_tag="LSX49_003339"
     CDS             2955..4256
                     /locus_tag="LSX49_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HBL7169713.1"
                     /translation="MFNFAVGRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IAAPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYSRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            4278..5423
                     /gene="glxK"
                     /locus_tag="LSX49_003340"
     CDS             4278..5423
                     /gene="glxK"
                     /locus_tag="LSX49_003340"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HBL7169714.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTIFPDAHYICLPIADG
                     GEGTVEAMVAATDGNIVKLEVCGPMGEKVNAFYGITGDGKTAVIEMAAASGLMLVVPE
                     KRNPLLASSFGTGELILHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQP
                     LAANGGNLARVASIEMNECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQLTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAV
                     NLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(5552..6337)
                     /gene="allE"
                     /locus_tag="LSX49_003341"
     CDS             complement(5552..6337)
                     /gene="allE"
                     /locus_tag="LSX49_003341"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HBL7169715.1"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFVN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFA
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYIPVEGHAPWLVYGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(6348..7583)
                     /gene="allC"
                     /locus_tag="LSX49_003342"
     CDS             complement(6348..7583)
                     /gene="allC"
                     /locus_tag="LSX49_003342"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HBL7169716.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKKMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDATVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL
                     VATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            complement(7605..8654)
                     /gene="allD"
                     /locus_tag="LSX49_003343"
     CDS             complement(7605..8654)
                     /gene="allD"
                     /locus_tag="LSX49_003343"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HBL7169717.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QKGVAVVGISRMGHSGAISYFVQQAARAGLIGISLCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSS
                     ELFRQHLSQTMRELNTITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     gene            8971..10638
                     /locus_tag="LSX49_003344"
     CDS             8971..10638
                     /locus_tag="LSX49_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HBL7169718.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAVMQQLEKALKQLAQGSGSSQAL
                     TQVRRWDSASQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLK
                     TRAREKGLLVMGPDCGTSMIAATPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAETVRLKIVNAMK
                     ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADGHQILDLGDDFYTVGRPHPMI
                     DPTLRNLLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPATQQHTPSLL
                     ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     gene            10648..11907
                     /locus_tag="LSX49_003345"
     CDS             10648..11907
                     /locus_tag="LSX49_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HBL7169719.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNKGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRTLAPQIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            11918..12733
                     /locus_tag="LSX49_003346"
     CDS             11918..12733
                     /locus_tag="LSX49_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HBL7169720.1"
                     /translation="MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPP
                     AHPQPLAVAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAAAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     gene            12730..13623
                     /locus_tag="LSX49_003347"
     CDS             12730..13623
                     /locus_tag="LSX49_003347"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL7169721.1"
                     /translation="MKTLVVALGGNALLQRGEALTAKNQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     gene            complement(14157..15224)
                     /gene="purK"
                     /locus_tag="LSX49_003348"
     CDS             complement(14157..15224)
                     /gene="purK"
                     /locus_tag="LSX49_003348"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBL7169722.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARQPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAE
                     RSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRAAETEQLPAECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQLQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NNPSVMINLIGSDLNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSHLTATLEA
                     LIPLLPPEYASGVMWAQSKFS"
     gene            complement(15221..15730)
                     /gene="purE"
                     /locus_tag="LSX49_003349"
     CDS             complement(15221..15730)
                     /gene="purE"
                     /locus_tag="LSX49_003349"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBL7169723.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     gene            complement(15826..16155)
                     /locus_tag="LSX49_003350"
     CDS             complement(15826..16155)
                     /locus_tag="LSX49_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169724.1"
                     /translation="MQRCNGFLISGIALTAGAPLCISWFGLVGFYFGALSLVAAAVIS
                     WIVYFWLIYLVLTRPHNQRFVERYILIVGICFLPWSIVLIWAFFASSARAHNQHAEQI
                     KNSTTDG"
     gene            complement(16266..16988)
                     /gene="lpxH"
                     /locus_tag="LSX49_003351"
     CDS             complement(16266..16988)
                     /gene="lpxH"
                     /locus_tag="LSX49_003351"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HBL7169725.1"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            complement(16991..17485)
                     /gene="ppiB"
                     /locus_tag="LSX49_003352"
     CDS             complement(16991..17485)
                     /gene="ppiB"
                     /locus_tag="LSX49_003352"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HBL7169726.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKDPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            17659..19044
                     /gene="cysS"
                     /locus_tag="LSX49_003353"
     CDS             17659..19044
                     /gene="cysS"
                     /locus_tag="LSX49_003353"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBL7169727.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMNDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            complement(19080..19601)
                     /locus_tag="LSX49_003354"
     CDS             complement(19080..19601)
                     /locus_tag="LSX49_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL7169728.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKAIPPRLLFAGIILAMLPDADVLS
                     FKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKWVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLP
                     GMLLMGMLWWRRR"
     gene            complement(19709..19921)
                     /gene="ybcJ"
                     /locus_tag="LSX49_003355"
     CDS             complement(19709..19921)
                     /gene="ybcJ"
                     /locus_tag="LSX49_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HBL7169729.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGLVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            complement(19923..20789)
                     /gene="folD"
                     /locus_tag="LSX49_003356"
     CDS             complement(19923..20789)
                     /gene="folD"
                     /locus_tag="LSX49_003356"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HBL7169730.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQGE"
     gene            21060..21136
                     /locus_tag="LSX49_003357"
     tRNA            21060..21136
                     /locus_tag="LSX49_003357"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21094..21096,aa:Arg,seq:tct)
     gene            complement(21152..21753)
                     /locus_tag="LSX49_003358"
                     /pseudo
     CDS             complement(21152..21753)
                     /locus_tag="LSX49_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415069.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            21760..22134
                     /locus_tag="LSX49_003359"
                     /pseudo
     CDS             21760..22134
                     /locus_tag="LSX49_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885581.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(22189..>22289)
                     /locus_tag="LSX49_003360"
     CDS             complement(22189..>22289)
                     /locus_tag="LSX49_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBL7169731.1"
                     /translation="EEGLTHILSEHFENVKTKVKGTVVMFSASGKK"
BASE COUNT         5116 a         5629 c         6073 g         5471 t
ORIGIN      
        1 atacgtgaaa ttaagaggga tttatggaac atcagagaaa actattccag caacgcggct
       61 atagcgaaga tctactgccg aaaacgcaaa gtcagcggac ctggaaaaca tttaactatt
      121 ttaccttatg gatgggttcg gttcataacg ttcccaatta tgtgatggtt ggcggctttt
      181 ttattctcgg cttgtctacc tttagtatta tgctggcaat tatcctcagt gcctttttca
      241 ttgccgcggt aatggtatta aacggtgctg cgggcagtaa atacggcgta ccgtttgcca
      301 tgatcctgcg tgcttcttac ggcgtacgtg gtgcactgtt tcccggatta ttaagaggcg
      361 gtattgctgc cattatgtgg tttggcctgc aatgttacgc ggggtcactg gcctgcttga
      421 ttctgattgg caaaatctgg ccgggatttt tgactctcgg tggcgatttc acgctgttag
      481 gcctttctct accgggatta attactttct tactcttctg gctggttaac gttggtattg
      541 gttttggcgg cggaaaagtt ttaaataaat tcactgccat tcttaacccg tgcatctata
      601 tcgttttcgg cggtatggcg atttgggcga tttcgctggt cgggatcggt ccaatctttg
      661 actacattcc gggcggtatt cagaaagcag aaaacagtgg cttcctgttt ctggtggtga
      721 taaacgcggt ggttgcggtc tgggcagcac cggcggtgag cgcatccgac tttacgcaaa
      781 acgcccactc gtttcgtgag caggcgctgg ggcaaacgct gggtttagtt gtggcctata
      841 ttctgtttgc ggtcgccggg gtatgtatta ttgccggagc cagtattcat tacggcgctg
      901 acacctggaa cgtgctggat attgttcagc gttgggacag cctgttcgcc tcgttctttg
      961 cggtactggt tattctgatg acgactatct ctactaacgc caccggtaat attattccgg
     1021 ctggttatca gattgccgcc attgcaccga cgaaactgac ctataaaaac ggcgtactga
     1081 ttgccagtat tatcagcctg ctgatctgtc cgtggaaatt aatggaaaat caggacagta
     1141 tttatctgtt cctcgatatt atcggcggaa tgcttggtcc ggtaattggt gtgatgatgg
     1201 cgcattattt tgtggtgatg cgtgggcaaa ttaatcttga tgaactgtac accgcacctg
     1261 gcgattataa atattacgat aacggtttta acctcaccgc gttttcagta actctggtgg
     1321 ccgttatttt atctcttggc ggtaagttta ttccctttat ggaaccgtta tcacgtgttt
     1381 catggtttgt cggcgtcatc gtcgcctttg cggcctacgc cttattaaag aaacgtacaa
     1441 cagcagaaaa aacaggagaa caaaaaacca taggttaatt aatcacgata ttgaacattg
     1501 agttaaaaac caatctgtat tttacaagga gtttgttatg tcttttgatt taatcattaa
     1561 aaacggcacc gttattttag aaaacgaagc tcgcgttgta gatatcgccg ttaaagacgg
     1621 aaaaattgct gctatcggcc aggatctggg cgatgcaaaa gacgttatgg atgcgtctgg
     1681 tctggtggtt tcgccgggca tggttgatgc gcacacccat atttctgaac cgggtcgcag
     1741 ccactgggaa ggttatgaaa ccggtactcg cgcagcagca aaaggtggta tcaccaccat
     1801 gatcgaaatg ccgctcaacc agctgcctgc aacggttgac cgcgcctcaa ttgaactgaa
     1861 gttcgatgcc gctaaaggaa agctgactat cgatgcggca caactcggtg gcctggtgtc
     1921 ttacaacatt gaccgtctgc atgagttgga tgaagtgggt gttgtcggtt tcaaatgctt
     1981 cgttgcgacc tgtggcgatc gcggtatcga caacgacttc cgtgacgtca atgactggca
     2041 attcttcaaa ggcgcgcaga agctgggcga actgggccag ccagtgctgg tgcactgcga
     2101 aaacgcgctg atctgtgacg cactgggcga agaagcgaag cgtgaaggtc gcgtaactgc
     2161 ccatgactat gtggcttcgc gtccggtatt taccgaagtg gaagcgattc gccgcgtact
     2221 gtacctggcg aaagtcgctg gttgccgtct gcacgtttgc cacgtcagca gcccggaagg
     2281 tgttgaggaa gtgactcgtg cacgtcagga aggtcaggat gttacttgtg aatcctgccc
     2341 gcattacttt gtgctggata ccgatcagtt cgaagaaatc ggtactctgg cgaagtgttc
     2401 accgccgatc cgcgatctgg aaaaccagaa aggcatgtgg gaaaaactgt ttaacggtga
     2461 aatagactgc ctggtttccg accactctcc atgcccgccg gaaatgaaag ccggtaacat
     2521 catgaaagcg tggggcggta tcgctggtct gcaaagctgc atggacgtga tgttcgatga
     2581 agcggtacag aaacgcggaa tgtctctgcc aatgttcggc aaattaatgg cgactaacgc
     2641 agcagatatt ttcggtctgc agcaaaaagg ccgtatcgcc ccaggaaaag atgccgactt
     2701 cgtcttcatt cagccgaata gcagctatgt tcttaccaat gacgatctgg aatatcgcca
     2761 caaagtcagc ccgtatgttg gccgtactat tggcgcgcgt atcacgaaaa ccatcttacg
     2821 tggtgatgtg atttacgaca tcgaacaggg cttccctgtt gcgccgaaag gtcaatttat
     2881 ccttaaacat cagcagtaat ctggccctgc aatgcccgtc cttgtggcgg gcattctccg
     2941 gttaaggtgt gtttatgttc aattttgcag tgggccgcga aagcctgtta tcaggattcc
     3001 agtggttttt ctttattttt tgcaacacgg ttgtggttcc tcctacgcta ctttctgctt
     3061 ttcagttgcc gcaaagtagc ctgcttacgc tcacgcaata tgcttttctt gctaccgcac
     3121 tggcctgctt cgctcaggcg ttctgcggtc atcgtcgcgc tattatggaa gggccgggcg
     3181 gcctgtggtg gggaaccatc ctgactatca cccttggcga agcatcgcgc gggacaccga
     3241 tcaacgatat cgctaccagt ctggcggtgg ggattgcgct ctccggcgtg ctgacgatgt
     3301 tgattggttt tagcggatta ggccatcgcc tggcacggtt atttacgccg tcggtgatgg
     3361 tcttgtttat gttgatgctg ggtgcgcaac tgaccactat ctttttcaaa ggtatgctcg
     3421 ggctgccgtt tggcatagcc gccccgaatt ttaaaattca attaccgccg ttcgcgctct
     3481 cggtggcggt gatgtgcctg gtactggcga tgattatttt cctgccacaa cgttttgccc
     3541 gttacggcct gctggtcggc acgataactg gctggttgtt gtggtacttt tgctttcctt
     3601 cttcgcattc gctctccggt gagttgcact ggcagtggtt cccgctcggc agtggcggtg
     3661 ctttgtcgcc ggggattatt ctgacggcgg tgattacagg tctggtaaat atcagcaata
     3721 cctacggtgc gattcggggc acggatgttt tttatccgca gcagggcgcg gggaatacgc
     3781 gttatcgtcg cagctttgtg gcgaccggat ttatgacact gataaccgtg ccgctggcag
     3841 taattccatt ttcaccgttt gtttcatcca ttggtttatt aacccagaca ggcgattact
     3901 cgcggcgttc gtttatttat ggcagcgtta tttgcctgct ggtggcactg gttccggcac
     3961 tcacgcgact gttttgcagt atccctttac cagtgagtag tgcggtcatg ctggtttctt
     4021 atctgccttt actcttttcc gcgctggtgt ttagccagca aataacgttt accgctcgca
     4081 atatttatcg actcgcattg ccgttatttg tcggcatatt tttaatggca ttaccgcctg
     4141 tgtatctgca agaccttcca ttaacgcttc gtcctctgct cagtaacggc ttactggtcg
     4201 gaattttact ggctgttctt atggataatc ttattccgtg ggaacgcatc gaataatttg
     4261 ttgaaaaagg attgataatg aagattgtca ttgcgccaga ctcttttaaa gagagcttaa
     4321 gtgcagaaaa atgttgtcag gcaattaaag ccgggttttc gaccatattt cccgatgcgc
     4381 actatatctg tttgccgata gcggatggcg gcgaagggac ggtggaggcg atggtcgccg
     4441 cgacggacgg taacatcgtg aagcttgaag tctgcgggcc gatgggcgaa aaagtgaatg
     4501 ctttttatgg cattaccggc gacgggaaaa cggcggtgat tgagatggca gcagcaagtg
     4561 gcctgatgct ggtcgtgcct gaaaagcgta atccgttgct ggcctccagt tttggtacgg
     4621 gggagttaat tctccatgcg ctggataatg gcattcgcca tattattctc ggcattggcg
     4681 gcagtgcgac ggtcgacggc ggtatgggca tggcgcaggc gctcggtgtg cgtttccttg
     4741 atgccgacgg tcagccgctg gcggctaacg gcggcaattt agcgcgcgtg gcaagtattg
     4801 agatgaatga atgcgatccg cgtctggcga actgtcatat tgaagtagca tgtgacgttg
     4861 ataacccgct ggtaggggca cgcggcgcgg cggcggtgtt tggcccgcaa aaaggggcaa
     4921 cgccggagat ggtcgaagag ctggaacagg ggctgcaaaa ttacgcccgt gttttacaac
     4981 agctaactga aatcaacgtc tgccagatgg cgggtggtgg cgcggcgggc ggtatgggca
     5041 ttgcggcggc ggtattcctc aatgcggata ttaaaccggg tattgagatt gtgttgaatg
     5101 cggtcaatct tgcgcaggca gtgcagggtg cagcactggt gatcaccggg gaagggcgca
     5161 tcgactcgca aacggcaggc ggtaaagcgc cgctgggtgt ggcatcggtg gcgaagcagt
     5221 ttaatgtccc ggtgattggg attgctggcg tattgggtga tggcgtggaa gtggtgcacc
     5281 agtacggcat tgatgcggta ttcagcattt tgccacgtct ggctccttta gccgaagtgc
     5341 tcgccagcgg tgaaaccaat ctcttcaaca gtgcgcgaaa tattgcctgc gccattaaaa
     5401 taggtcaggg aattaaaaac tgactattac ctttaaagcg gatgcgattt atatcgcatc
     5461 tttttttacc tgaattgact acaaaaaaag ccacggaata aaccgtggca aaatccaaca
     5521 tagctaaaaa taatcaggcg agtggtatga cttaaatctc tacgtcgcgg ttgcaatctt
     5581 tcgagtaaat atagctgaac gcttcaccac gccctacgcc ataaccagcc tgtaaagaat
     5641 aagcgcccat aaagatgtaa tcgccttttt tcaccgggat ccagttattg tcgaggttat
     5701 aaaccccctg accggaaaga atataggcac cgtgttcctg aacgtgggtt tcgatataac
     5761 cgtggctggc acctggtgca aaagagagga tatgcatgtt catatcaaaa cctaactctt
     5821 tgggcagaaa atccagcaga ataacatcgt ccatgccttc ataatgaatg cgttccagtt
     5881 cgctggcatt gccataaacc agccacggcg catgaccttc taccggaata tagcgacgct
     5941 tatataaaaa gatttggctg tcttcggcct gggcgttaac aaacgtcatt aaggagcctg
     6001 gcgggcaata aagatagcca ccttcgctta aggcaaatgt tttcccttcg gctttggcag
     6061 tgatatttcc agagatcaca tacaggaacg tttcaatgcc ttcgccaccg aagccctgtt
     6121 ggttgccgcc gttttgatgc agtgtgacca gataatcaac aaaagaggca cccagctttg
     6181 gcgtggagag gattgtcgcg tcacaattta caaagcccgg aataatattt tttaccagac
     6241 cgtctggtgt taacagtgcg aaattaccgt gtttaacaat cgcacggtta gccagtaaat
     6301 catcgcggta accggtgacg ttatttaaat atcccattta taactcctta tttctgccag
     6361 gcaagttgat aaagcatgag tgccaacgtt ttgacccctt cggcaaggtc ggtaatattg
     6421 gtgcgttccg ccgggttatg gctgatcccg ttgatgctgg gaatgaaaat catgcaggtc
     6481 ggcacgcgag gcgcgaaaat ttgcgcgtcg tgcccggcac cactgtgcat cacccggtaa
     6541 ttcagttttt cgctttcaca caattctgtc agggtggcga ccagctcctt attcatcggc
     6601 acgggttctt cgtccatcca taaatcgata tcaataccaa tatccatttc atcgcaaatc
     6661 gcccgcatgt cgttttctaa ctgttgggtg aaatcgcgca gcacggtagc atcggtatga
     6721 cgacaatcaa tggtgaacgt ggttttaccc ggcactacat tcaccgtatt cgggcgcggc
     6781 tctactttgc caaaagtcag aaccagcggg tcgcccatct ttttcgcttt ttcgacagac
     6841 tgatggcaaa tgcgactgaa agcgtaaacc gtatcacgac gataacccat cggcgtggtg
     6901 cctgcatggt ttgattcacc gttcagcgtc accgtatagc gacgttgccc gacaattgca
     6961 ttcaccacgc caattgactg cccattactt tccagcacac agccctgttc gatatgcagt
     7021 tcgacaaagg ctttaatatc ctgacgcgga gttagtgggg cgttcggcag agtaaatccg
     7081 caagccttca tcgcatcgac aaaactattt cctttggcat cacagatatt ccgcacgtcg
     7141 tcaggattcg ccagcccaaa aatattttta ctgccccaga aaacatacgg gaagcggctg
     7201 ccttcttctt ctgccatcgc caccacttcg accgtacgta acggcgcgcc gtattgcgtt
     7261 ttcagccagt caattgccag ccacgccgcc agcgcaccga attgcccgtc gaggttaccg
     7321 ccgttaacca cggtatcgat atgcgaaccg ctcagaacca cttcctgtgg atattcggtg
     7381 ccattcaggc gaccgtataa attccccact tcatcgaaac gtgtttccag cccgcttgct
     7441 gccattcttt ttttaaactg ctgctgggtt tccagccatt ccggcgaata aagtaaacgg
     7501 gtcatcccac ccgctgggtc agcgccaaaa gaggaaagcc agggcagcgt ttcttctata
     7561 gcttgacgga aatgtgtaat cataagaaag tcctgtctca ataattattg cgcaaaggga
     7621 tttttcgttt cgtatgacgt gttataaagc gcgtcggaaa ttaaatactg gtaaatatca
     7681 tcaacaattt cgatgccttc gacggcggct ttgcgttgtt taatatcctg atcctgtccg
     7741 ggataataaa cctgattaaa accgggcgcg ggggtaatgg tatttaattc gcgcatggtc
     7801 tggctaagat gttgacggaa taattcgctg gaggagaaaa agttcgggtt aataactata
     7861 tgtaattgcc ccaaattacg cccggcgtgt aaatcgtcat acatcgaact aacctgtcgc
     7921 ccgaacggta agccgagtaa gacgcctgag aggacgtcaa tcatcatcat caggccatac
     7981 ccttttggcc cagcggcggg gagcagagca tgtaccgcga acggatcggt tgttggtgca
     8041 ccgtttttat cgactgccca ggtatccggg atagacatat tgcgcgagcg ggcgtcgagt
     8101 acttttcccc atgcctgtac ggtagtcgcc atatcaaagg taaggatctc gtcgccttct
     8161 cccggcgcgg caaaggccag tgggttagtg ccgtagtaaa tttccgcgcc gccaaacggc
     8221 accaccattg gatcggactg gcacagcgaa atgccaatca atccggcgcg ggcagcctgc
     8281 tgcacaaaat aagagattgc gccgctgtga cccatccggc tgataccgac caccgcaacg
     8341 cctttttgct gggcggtttt gatggcatgt tccataccca ttttcgccgc gacctgtccg
     8401 gcggcattgt cggcatgtaa aattgccgag cacggtccgg tttcctcaag acgaaactcc
     8461 ggttcgcggt tggtgccgcc ttttgaaatg cgttcggcgt agtattcaac gcgcaccgcg
     8521 ccatgagagt ggatccctct ggcatcggcg taaaccaata cttcagccac ggttgcagcg
     8581 tgctcacgtt ttaacccagc ctggcagagt ttattctcga ttagctggtg gagtgtttcc
     8641 cgactgattt tcatctgtct tcctttttaa cgacggtgtg aagcatgact gcaattaaca
     8701 tacagggaaa atatctggat tatgtgatcc agacaggcaa aaaaatatag ttagaattta
     8761 tttgataatc ttcgtgcttt taacctggtt tttaaaacaa ccatgcttat taaaaaataa
     8821 cgcgtaatag tctggcggtt atttgaattc ttttgttaat aatccccgtg tgatattcat
     8881 caccttattt actcgttgtc atcgataccg taatcgccac attaacactg ctcgtgcaat
     8941 tgccatgggt gcaattttta aggagttgtt atgatccacg cctttattaa aaaagggtgt
     9001 tttcaggatt cggtcagttt aatgattatt tcacgaaaac tcagcgaatc agaaaatgtt
     9061 gatgatgttt ccgtaatgat gggtacgccc gccaataaag cgttattaga tactacaggt
     9121 ttctggcatg acgattttaa taacgccacg ccgaacgata tttgcgtggc aattcgtagc
     9181 gaagcggcgg atgcggggat cgcgcaggcg gttatgcagc agcttgaaaa ggcgctaaaa
     9241 caactggcgc agggttcagg cagcagccag gcgttgacgc aggtgcgtcg ctgggacagt
     9301 gccagtcaga aattacccga tgccaatctg gcgctgattt cagtggctgg tgagtatgcg
     9361 gcggagttgg cgaaccaggc gctggatcgc aacctcaacg tgatgatgtt ctccgataac
     9421 gtcacgctgg aagatgaaat ccaacttaaa acccgcgcgc gggaaaaagg cttgctggtg
     9481 atggggccag actgcggtac gtcgatgatt gctgccacgc cgctggcttt tgctaatgtg
     9541 atgccggaag gcaacattgg cgtcataggc gcttccggta ccgggattca ggagctgtgc
     9601 tcacagattg cgctggcagg ggagggaatt actcacgcga ttggtcttgg cgggcgcgat
     9661 ctcagccgtg aagtgggcgg catcagtgcg ctaacggcgc tggaaatgct cagtgcagac
     9721 gagaaaagcg aagtgctggc atttgtttca aaaccacctg ccgaaactgt gcgtctgaaa
     9781 attgttaatg ccatgaaagc aactggcaaa ccgacggtgg cgctgttttt aggttatacc
     9841 ccggcggtgg cccgcgacga gaatgtctgg tttgcctcct cgctggatga ggccgctcgt
     9901 ctggcttgtc tgctttcacg cgtcactgcg cgacgtaacg cgatagcgcc tgtcagcagc
     9961 ggatttattt gcggtttgta taccggcggt acgctggctg ctgaagcggc gggattactt
    10021 gccggacacc ttggcgtgga agccgacgat acccatcaac atggcatgat gctggacgcc
    10081 gacggacatc agatcctcga cctgggcgat gatttttaca ccgtcgggcg tccccatccg
    10141 atgatcgacc cgaccttacg caacctgtta attgccgatc tcggcgctaa accgcaagtg
    10201 cgagtgttgc tgcttgatgt cgtgattggc ttcggcgcga ccgccgatcc tgccgcctcg
    10261 ctggtgagcg cctggcaaaa agcctgtgcc gcgcgttcag acaatcaacc actgtatgcc
    10321 attgccacgg tgacaggcac tgaacgtgac ccgcaatgcc gctcgcagca aatcgccacg
    10381 ctggaagatg cggggatcgc ggtagtgagt tcgctaccgg aagccacctt gctggctgcg
    10441 gcgttaattc atccgctctc gcctgccaca cagcaacaca caccgtcatt actggaaaac
    10501 gtcgccgtga ttaacatcgg attacgcagc tttgcgctgg agctacaaag cgccagcaaa
    10561 ccggttgtgc attaccaatg gtcgccagtc gccggcggca ataaaaaact ggctcgttta
    10621 ttagaacgtt tgcaataagg ggttcccatg tttacatcag tggcgcaagc caatgctgcg
    10681 gttatcgaac aaattcgtcg tgctcgtcca cactggctgg atgtgcaacc ggcttcttca
    10741 cttatcagcg aactaaacaa gggcaaaaca ctgcttcacg ccgggccgcc aatgcgctgg
    10801 caggagatga ccggacccat gaaaggggcg tgcgtgggcg catgtctgtt cgaaggctgg
    10861 gcgaaagatg aagcgcaggc gctggcaata ctggagcagg gggaagtgaa cttcattcct
    10921 tgtcaccatg tgaatgccgt cgggccaatg ggcggcatta cttctgccag tatgccgatg
    10981 ctggtggtcg agaacgtgac cgacggcaac cgggcgtact gcaacctcaa cgaaggtatc
    11041 ggcaaagtga tgcgttttgg cgcttacggc gaagatgtcc tgactcgcca tcgctggatg
    11101 cgcgatgtgt taatgccagt attaagcgcg gcgctggggc gcatggagcg cggtatcgat
    11161 ctcacggcaa tgatggcgca gggcattacc atgggcgatg agttccatca acgcaatatt
    11221 gcttcctcag cactgttaat gcgtacgctg gccccacaaa ttgctcgcct cgatcatgat
    11281 aaacagcaca ttgcggaagt gatggatttt ctcagcgtga ccgatcagtt cttcctcaac
    11341 ctcgcgatgg cctactgcaa ggcggcgatg gatgcaggcg cgatgatccg cgcaggcagc
    11401 atcgttacgg ctatgacccg caacggcaat atgttcggga ttcgggtaag cgggctgggt
    11461 gaacgctggt ttactgcgcc tgtaaacact ccgcaaggtc tgtttttcac cggcttctcg
    11521 caggagcagg cgaacccgga tatgggcgat agcgcgatta ccgaaacctt tggtatcgga
    11581 ggtgcggcaa tgatcgcagc gcctggcgta acgcgctttg tcggtgcggg tggcatggaa
    11641 gcggccagag cggtatctga agagatggcg gaaatttacc ttgaacgcaa tatgcagttg
    11701 cagatccccg gctgggattt ccagggggcg tgcctggggc tggacattcg tcgcgtggta
    11761 gaaaccggca ttacgccact catcaatacc ggtatcgccc ataaagaggc ggggatcggg
    11821 cagattggcg caggcaccgt gcgggcaccg ctggcgtgct ttgaacaggc gctggaagca
    11881 ctggctgaaa gcatggggat tggttgagga acgcacaatg acgatcatcc atcctctgct
    11941 tgccagccgt agcgcaccga attatcgcca gtcctggcgg ttagcgggag tgtggcggcg
    12001 ggcgattaac ctgatgacgg aaagcggcga actgttaacg ctgcatcgtc aggggagtgg
    12061 tttcggcccc ggcggatggg tgcttcgccg cgcgcaattc gatgcgttat gcggtggatt
    12121 atgcggcaat gaacgaccac aggttgtggc acaaggtatt cgtctcgggc gtttcacggt
    12181 taaacagcca cagcgttatt gtttgctacg tattacgccg cctgcgcatc ctcaaccgct
    12241 tgccgttgca tggatgcaac gcgcggagga aaccgggctt ttcgggccac tggcattggc
    12301 ggcaagcgat ccgctgcctg ctgaattacg ccagtttcgt cactgttttc aggccgcgct
    12361 caatggcgtt aagaccgact ggcggcactg gctgggtaaa ggccccggat taacgccaag
    12421 tcatgatgac acgctgagcg gaatgctgct ggcggcctgg tattatggcg ctttagatgc
    12481 gcgctccggt cgcccgtttt ttgcctgttc cgacaatctt caactcgtta ccactgcggt
    12541 gagcgtcagt tatttacgtt atgccgcgca aggatatttc gcctcgccac tcctgcactt
    12601 tgttcatgcg ctgagttgcc cgaaacgtac cgcagcggcg atcgattcgc tgctggcgct
    12661 ggggcatacg tcaggggcag atacgctgct ggggttctgg cttggccaac aattattaca
    12721 agggaaacca tgaaaacact ggttgtggct cttgggggca acgccttact ccagcgcggt
    12781 gaggcgctga cggcaaaaaa tcaatatcgc aatattgcca gtgctgtacc cgcgctggcg
    12841 cgcctggccc gttcttatcg gctggcaatt gttcacggca acggaccgca ggtggggctg
    12901 ctggcgttac agaatctggc gtggaaagag gtagaaccgt atccgctgga tgtactggtg
    12961 gcggaaagcc aggggatgat tggctatatg ctggcgcaga gcttgagcgc acagccgcag
    13021 atgccgcctg tcacgacggt gctgacgcgc attgaggttt cgcctgatga tccggcgttt
    13081 ttacagccag agaagtttat cggtccggtt tatcagccag aagaacaaga ggcactggaa
    13141 gcggcttacg gctggcagat gaaacgtgat ggtaaatatt tacgtcgggt ggtggcgtct
    13201 ccgcaaccgc gtaaaattct cgacagcgaa gccatcgagt tgttgctcaa agaggggcat
    13261 gtggtgattt gcagtggcgg cggtggtgtg cctgtgacgg aagacggggc agggagtgaa
    13321 gcggtgattg ataaagatct cgccgctgcg ttgctcgccg agcagattaa tgccgatgga
    13381 ctggtgatcc tcaccgatgc tgatgcggta tatgaaaact ggggaacgcc gcagcaacgt
    13441 gccattcgcc atgccacacc ggatgagtta gcgccatttg ccaaagccga tggttcgatg
    13501 gggccgaagg taacggcggt gagtggctat gtcagaagcc gtggtaaacc cgcgtggatt
    13561 ggggcgttat cgcggattga agagacgctg gcgggcgaag cggggacttg tatttcgctg
    13621 tagtgatggg caccaggcaa ttggcacatc tagcctgatg cgatgctggc gcgtcttatc
    13681 aggtctacag gcggtgtcgg aacggtaggc cggataaggc gttcacgccg catccggcaa
    13741 tcggcacacc atgcctgatg cgatgctggc gcgtcttatc aggcctacag tcggtgtcgg
    13801 aacggtaggc cggataaggc gttcacgccg catccggcaa tcggcacacc atgcctgatg
    13861 cgatgctggc gcatcttatc aggtctacag gcggtgttgg aacggtaggc cggataaggc
    13921 gttcacgccg catccggcaa tcggcacacc atgcctgatg cgatgctggc gcgtcttatc
    13981 aggtctacag gcggtgtcgg aacggtaggc cggataaggc gttcacgccg catccggcaa
    14041 tcggcacacc atgcctgatg cgatgctggt gcgtcttatc aggtctacag gcggtgttgg
    14101 aacggtaggc cggataaggc gttcacgccg catccggcaa tcaaatgagc accaggttaa
    14161 ctgaacttac tctgcgccca catcacgccg ctggcatact ccggtggcag cagcgggatt
    14221 aaggcttcca gcgtcgcggt cagatgcgat gtgtcgctgt cggtcaaatt taaatgcccc
    14281 actttacggc ccggacggac ttctttgtcg taccagtgca gatgcacaag cggcagtttc
    14341 agccagtcat aattcagatc gctaccaatc agattgatca tcaccgacgg attattcact
    14401 actggttgcg gtaacggcag atcggtaatt gcccgcagat gtagctcaaa ctggctgatg
    14461 ctggcaccgt tttgcgtcca gtgcccactg ttatgcacac gcggagccag ttcgttgatc
    14521 agcagacctt gcggcgtgac aaaacactcc atcgccatca cgcccacata gcccagctcc
    14581 tgcataatcg ccgacaacat ctcttcagct tgcgcctgca gctgtgcgtt ggcctgcggg
    14641 aaagcgacgc tggtgcgcaa aatgccgtcc tgatgcaggt tatgcgtcag cggataaaac
    14701 acggtgctgc catcaaaacc gcgcgcgcca accagcgaca cttcacctga gaagtttatg
    14761 ccctgctcga caatacattc gccgtagcat tcagccggta actgttcggt ttcagcggcg
    14821 cgtaaacgcc attgaccgcg tccgtcatag ccaccagtgc ggcgcttaac aatcgccagc
    14881 tcacctaaac gatcaaacac cgcaggccac tcgctgcgtt cggcaagtaa ctgccacggt
    14941 gcggtcggca ggtggagctt atcgaaaagc tgcttctgag tcagacggtc ggcaataatc
    15001 gggaacacat cgcggttcac aaaggccggc tggcgcgcca gctcgcgggt taatgcagtt
    15061 tccggccagc gttcgatctc agcggtaatc acgctttgtt gaaaaggcac cgccgccggt
    15121 tcagcgtcca gcccgaccgg ccagacagca atgcctaacg gttcgcctgc ctgacgcagc
    15181 atacggccta actgcccgtt accgaggacg caaacctgtt tcatgccgca cctcgcgggt
    15241 ccgggttttc cagcacttca tcagtttgtg ctttgcgcca gtcattcaga cgctggtgca
    15301 gttctttatc atgagtcgca agaatttgtg ctgccagtaa cgccgcgttt gccgcgccag
    15361 ctttaccaat cgccagcgta cccaccggaa tgccgcgcgg catttgtacg atggagtaga
    15421 ggctatcgac accgctcagt gcggcgctct gtactggcac gcccagcacc ggcaccagcg
    15481 ttttggcggc aatcatgcca ggcaggtgcg ctgcgccgcc tgcgcccgca ataatcacct
    15541 gataaccgtt ctcttcggcg ctttcggcga agctgaacag tttatcgggg gtgcggtgag
    15601 cagaaaccac ttcaacgtgg tgcgggacat tcaggatttc gaagatttcg gcggcgaact
    15661 gcatggtagc ccagtcgctt ttggacccca tcacgatggc gacacgcgcc ggattattgc
    15721 gggaagacat gcgtcttaaa actcctgtgg tgcacaactc tcggctttag agggcacaga
    15781 gaatagcacg gaaagagtgc taggaaaacg gttgcgtagg cggaattaac cgtcagttgt
    15841 tgagttttta atttgttctg cgtgttgatt atgcgctctg gctgaactgg caaagaatgc
    15901 ccatatcagc acaatgctcc acggtaaaaa gcatataccg acaatcaata tatatctttc
    15961 tacaaagcgt tggttatggg ggcgggtgag tactaaataa atgagccaga aatagactat
    16021 ccaggaaatg accgccgcag ctaccagtga caatgcgcca aaatagaagc cgacaagacc
    16081 gaaccagcta atacacagtg gcgctcctgc cgtaagggcg atgccagaaa tcaaaaatcc
    16141 gttgcagcgt tgcataataa tattccctgt tgttatttca ctcagagatt attaccttgc
    16201 tgattttaaa aaagatatac aggttgcgtt agttcggtgc tttttcagaa tctgtccatt
    16261 cgtggtcaga aaggaaaatg gattagctca acgtcatccg ccgtgacttt caccatcgaa
    16321 ccttctgtat gccaggcacc cagtaccacg cgaaaagcag gttgctgatt ggcgataagt
    16381 tcatgcaccg ccgggcgatg ggtatgcccg tggatcagcc attgcacttg atgtttttcc
    16441 atcgcactga ccaccgcgtt ttggttaacg tccatgatcg ccagcgattt actgctgttg
    16501 gcttctttac tgttcgcgcg cattcgcgcg gcaatgcgtt tgcgcacaaa caacggcagg
    16561 gcgaggaata gcgtttgcag ccagggtttg tggactttgg cgcgaaaagc ctgataaccc
    16621 gcgtcatcgg tgcacagcgt gtcgccatgc ataatcaaca cccgacgacc ataaagttcg
    16681 agcacctttt cttccggcaa taacgtcatg ccgctttcac gggcaaagcg tttgccgagc
    16741 agaaaatcac ggttgccatg aatgaaataa cagggaacgc cggaatcgga taccgctttg
    16801 atcgctgcgg ccatctggtg atgaagtggg ttgggatcgt cgtcgccgat ccaggcttca
    16861 aacagatcgc caagaatata cagcgcatcg gccttgcggg cctcccctgc taaaaaacgc
    16921 agaaaaccgg cggtgatcgc cggttcttcc acgcagagat gaagatctgc aataaagagt
    16981 gtcgccacga ttactcgcta acggtcacgc tttcaatgat aacgtcttct tttggcacgt
    17041 cctggtgcat accgctacga ccggttgcca cacctttgat tttgtctacc acgtccatgc
    17101 cttcaaccac ttcagcaaat acgcagtagc cccaaccttg caggctttcg ccagagaagt
    17161 tcaggaagtc gttatcaacc acgttgatga agaactgggc agttgcagag tgcggtgcct
    17221 gagtacgggc cattgccagc gtaccacggg tatttttcag accgttgttc gcttcgtttt
    17281 tgatcgggtc tttggtggct ttttgtttca tgcccggttc aaaaccgccg ccctgaatca
    17341 taaagccgtt gataacacgg tggaaaatgg tgttgttgta aaaaccttcg cggcagtagt
    17401 ccaggaagtt tttaactgtt tcaggtgctt tatcgtcaaa agttttgatg acaatatcgc
    17461 cgtgattggt gtggaaagta accatttttg catcctgttc cgtttgattg gtgcttcaac
    17521 ccggttcggg tcatatatag ggtggtgtta tagcataacc gcacgatcgg atcatctcgc
    17581 aatgtatgct gattcgcgcg ggaaatatgg gtattatacg caactcaatt acccacacat
    17641 gtctaaacgg aatcttcgat gctaaaaatc ttcaatactc tgacacgcca aaaagaggaa
    17701 tttaagccta ttcacgccgg ggaagtcggc atgtacgtgt gtggaatcac cgtttacgat
    17761 ctctgtcata tcggtcacgg gcgtaccttt gttgcctttg acgtggttgc gcgctatctg
    17821 cgtttcctcg gctataagct gaagtatgtg cgcaacatta ctgatatcga cgacaaaatc
    17881 atcaaacgcg ccaatgaaaa tggcgaaagc tttgtggcgc tggtggatcg catgatcgcc
    17941 gaaatgcaca aagattttga tgctttgaac attctgcgcc cggatatgga gccgcgcgcg
    18001 acgcaccata tcgccgaaat tattgaactc actgaacaac tgatcgctaa aggtcacgct
    18061 tatgtggctg acaacggcga cgtgatgttc gacgtcccga ccgatccgac atatggcgtg
    18121 ctgtcgcgtc aggatctcga tcagctgcag gcaggcgcgc gcgttgacgt ggtcgacgac
    18181 aaacgcaacc cgatggactt cgttctgtgg aaaatgtcga aagagggcga acctagctgg
    18241 ccgtctccgt ggggcgcggg ccgtcctggc tggcacattg aatgttcggc aatgaactgc
    18301 aagcagctgg gtaaccactt tgatatccac ggcggcggtt ctgacctgat gttcccgcac
    18361 cacgagaacg aaattgccca gtccacctgt gcgcacgatg gccagtatgt gaattactgg
    18421 atgcactccg gtatggtgat ggttgaccgc gagaagatgt ctaaatcgct gggtaacttc
    18481 ttcaccgtgc gtgatgtgct gaaatactac gatgcggaaa ctgtgcgtta cttcctgatg
    18541 tcgggtcact atcgcagtca gttgaactac agcgaagaga acctgaaaca ggcgcgtgcg
    18601 gcgctggaac gtctctacac tgcgctgcgc ggcacagaca aaaccgttgc gcctgccggt
    18661 ggcgaagcgt ttgaagcgcg ctttatcgag gcgatgaacg acgatttcaa cactccggaa
    18721 gcctattccg tactgtttga tatggcgcgt gaagtgaacc gtctgaaagc agaagatatg
    18781 gcagcggcga atgcaatggc gtctcacctg cgtaaacttt ctgccgtatt gggcctgctg
    18841 gagcaagaac cggaagcgtt cctgcaaagc ggtgcgcagg cagacgacag cgaagtggct
    18901 gagattgaag cgttaattca acagcgtctg gatgcccgta aagcgaaaga ctgggcggcg
    18961 gcagatgcgg cgcgtgaccg tcttaacgag atggggatcg tgctggaaga tggcccgcaa
    19021 gggaccacct ggcgtcgtaa gtaattgcgc tattgccgga tgcgagtttt cgcatccggt
    19081 tatcgtctgc gccaccacaa cattcccatc agtaacatcc ccggcaacca cacccacatc
    19141 aattcagaaa taatcacctg atgcccgtac ggcgtggtgt aacgagacaa tgcaaacggc
    19201 gcgactttaa tcacctgcca gggagcgaaa aagcgttcat ctgaccacgg ccacagccag
    19261 ccaacccatt taccgccagt ggttaccgaa tccagcaagc tgtgcgatag caacgagacg
    19321 gttaaaaaca gccagcagcg aatcagccca gccctgaacc atcgacgtcc aatcagcaca
    19381 cataacagcg ggacaacaaa cgcaaacacc agcgaatggg taaacccgcg atgaccaaaa
    19441 acatttccgt aagcaacgcc aaatttaaac gacaatacat cggcatcggg cagcatcgcc
    19501 aggatgattc cggcaaataa cagacgcgga gggatggctt tcgaacccaa ccctaaacca
    19561 atgcataggg gaacggcggc gtgcgtaata acggttggca tgatggtcgc ttcggcaaaa
    19621 tgtcgatgct atcagcatgg atgaacgggg cgtagagggc aaaagtctga aaagagaacc
    19681 ggcctgttga tacaggccgg gaaagggatc aggcaacaac ctgtacgctg tgacctgcaa
    19741 aactcactgt ctgaccggcg acgattttgc agcgtttgcg cgtttcaacc gcaccgtcga
    19801 ctttcaccag gccttcggct atcgcgattt tcgcctgcgc gccgctttcg ctccagcctt
    19861 ccagtttcag caagtcgcac agctcaacgt gcggatgttt acctaaagaa aatgtcgcca
    19921 tgttactcac cctgtggatc atgatattca acgcacgcct gtagcgtgtt ttcaatcagc
    19981 gtggcaaccg tcatcgggcc aacgccgccc ggaacaggcg taatgtatga ggcgcgttta
    20041 gccgcgtctt caaacacgac gtcgcccaca actttgccat tttccagacg gttgatgccg
    20101 acatcaatca caattgcgcc ttctttgatc cagtcaccag gaataaagcc cggcttgccg
    20161 acggcaacga tcaacaaatc ggcattttct acgtggtgac gcagattttt agtgaaacgg
    20221 tgagtcacgg tggtggtgca acctgccagc agcagttcca tgctcattgg gcgaccgacg
    20281 atattcgatg cgccaatcac cacggcgtta aggccgaagg tatcaatgtt gtaacgctca
    20341 agcagcgtga cgataccgcg cggggtgcag ggacgcagac gtggcgcgcg ctggcacaga
    20401 cgaccgacgt tgtaaggatg gaaaccgtcc acgtctttgt ccggatgaat acgttccagc
    20461 actttgacgt tatcaatacc cgccggtaac ggcagttgaa ccagaatgcc atcaatggtg
    20521 ttgtcggcat tcagcgcatc gataagctcc agcagctccg cttcgctggt ggtttccggg
    20581 aggtcataag agcgggagac gaacccgact tcttcacaag ccttgcgttt gcttgcgaca
    20641 taaatttgcg atgcagggtt gctacccacc agcacaacgg ccagtcctgg cgcccgcagt
    20701 ccggctgcaa tacgcgcctg aactttttga gcaacttcag agcgcacctg ctgcgcaatc
    20761 gttttaccgt caataatctt tgctgccatc agagagagga ttccatctgt tacgtaggtc
    20821 gaaggggatg cgcctatttt gtcagaagcg tggcgcgctg tcagttttcg ttttctgaaa
    20881 agtaaaacct tctgtacctg gctgattcac acctatcatg ataaccgtcg ttggtttgcc
    20941 gccatagtga gctacatctg atgcggtcgt acacttgttc agcaactggt tcaaaagcca
    21001 ttgactcagc aagggttgac cgtataattc acgcgattac agcacaccgt ggtatcaatg
    21061 cgcccttagc tcagttggat agagcaacga ccttctaagt cgtgggccgc aggttcgaat
    21121 cctgcagggc gcgccattaa aattcaatca gttacgcctt ctttatttct tctataattc
    21181 cagagtggga cattatcacc aaaaatgtcg tctattttcc tcgcgtgctc agtcaaatga
    21241 ttaggcgcaa ggtgagcata tctacgaacc atttctctgg actcccatcc gcccatttcc
    21301 tgaagcactg ataatgggac gcctgacgga atcaacctgc ttgcccgggt atgccagagg
    21361 tcatggaaac ggaaattttc aactcctgca cgacgacaag ctgatagcca tgctgtcttg
    21421 ctgtcaatgc gcatcttcct gagcgcaggc attgatgttc catctgctcg cttagccgcc
    21481 ctggtatgta cacccacatt tgtgatgctt gcctgtttga tcacgcaaca ctttagaggc
    21541 ggtatcgttc agcgccacac caatggcgcg atttgatttg ctatcttctg gatccaccct
    21601 ggcaacttgt cgctgcatgt caatctgttg ccactccaga tttatgatgt tcgactttct
    21661 cagaacagtt accagcgcaa atttgacgac agatttcagt agttcggggc tctcatcaat
    21721 caggcgtttt gcctgattct tttgtaagtc tcttgtgcca ttccacctca tacaggtttg
    21781 cctgcaaaca gtaccgatat tgcaccgcca gatattccgg ctggcttcgt ggttgttttc
    21841 aacagtgatg aggcatcgtg gcatctcgtt gaagaccatc tgggtaaaac ggtttatgac
    21901 gtggcatcag gggacgcgtt atttatttct gaactcggtc cgttaccgga aaatgtcacc
    21961 tggttatccc cggcagggga gtttcagaag tggaacggca catcatggat aaaggatacg
    22021 gaggaagaaa cctcgttgct ggaagcctgg aagatgtatc gggtgttgct gaaccgagtt
    22081 gatacatcaa ctgcccctga tattgagtgg cctgtgaacc ctgtcagaga gtaatcattg
    22141 ggattatgcc gcagcacgtc gtgcgcaaga acgtgctgcg tctggatgct attttttccc
    22201 tgaagcggaa aacattacta cagtaccttt aaccttggtt ttaacattct cgaaatgctc
    22261 tgagagtata tgtgttaagc cttcttcgg
//
LOCUS       DAFGPF010000079        22262 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFGPF010000079 DAFGPF010000000
VERSION     DAFGPF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22262
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.079"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..581
                     /locus_tag="LSX49_003361"
     CDS             <1..581
                     /locus_tag="LSX49_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707161.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HBL7169732.1"
                     /translation="VTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE
                     KPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSV
                     ASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVK
                     NAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ"
     gene            complement(621..1019)
                     /gene="yciA"
                     /locus_tag="LSX49_003362"
     CDS             complement(621..1019)
                     /gene="yciA"
                     /locus_tag="LSX49_003362"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HBL7169733.1"
                     /translation="MSTAHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(1124..1663)
                     /locus_tag="LSX49_003363"
     CDS             complement(1124..1663)
                     /locus_tag="LSX49_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HBL7169734.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQSVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            complement(1693..2436)
                     /locus_tag="LSX49_003364"
     CDS             complement(1693..2436)
                     /locus_tag="LSX49_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HBL7169735.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAVLLIYLFRLYMLIRQ"
     gene            complement(2464..2553)
                     /locus_tag="LSX49_003365"
                     /pseudo
     CDS             complement(2464..2553)
                     /locus_tag="LSX49_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            2792..3430
                     /gene="ompW"
                     /locus_tag="LSX49_003366"
     CDS             2792..3430
                     /gene="ompW"
                     /locus_tag="LSX49_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HBL7169736.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAASPFRHKVGTATTGDIATVHHLPP
                     TLMAQWYFGDSGSKFRPYIGAGINYTTFFNNDFNDTGEGLGLSDLSLKDSWGVAGQVG
                     LDYLINRDWLLNMSVWYMDIDTTAKYKSGVTTVKDSVRLDPWVFMFSAGYRF"
     gene            complement(3476..4606)
                     /locus_tag="LSX49_003367"
     CDS             complement(3476..4606)
                     /locus_tag="LSX49_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HBL7169737.1"
                     /translation="MARPRKYKTNVPGLSPYFDKRNNKVYWRYRHPITGKNHGLGSID
                     QKLAETIAAEANSRLARQQMEQMLSLQEKIISDTGGSSTVTIFLNNYRKIQQERYENG
                     EIKLNTLKQKAAPLRVFDERFGTRPLDAITVKDVVSVLEEYKARGHNRMGQIFRKVLI
                     DVFREAQQTGDVPPGFNPAESAKKPQVRISRQRLTFDEWMMIYNAAEKDGYFLQRGML
                     LALMTGQRLSDICKMQFSDIRDGYLHVEQQKTGTRIAIPLALRCDKLNLTLDDVVSSC
                     RDCVLSPWLLHHHHAKGTAKRGGMVKPATLTVAFKKARDSVDYNWRANGTPPSFHEQR
                     SLSERLFREQGVDTKILLGHSNQKMTDIYNDARGKEWKKLVI"
     gene            complement(4584..4832)
                     /locus_tag="LSX49_003368"
     CDS             complement(4584..4832)
                     /locus_tag="LSX49_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBL7169738.1"
                     /translation="MARLILLTEWAKEEFSEPVPTPSTLSKYAKAGMIFPLPKKVGRR
                     WRVDPQARFVGMVNKPEVIATDHPALKRILEDGAPAKI"
     gene            complement(4897..7368)
                     /locus_tag="LSX49_003369"
     CDS             complement(4897..7368)
                     /locus_tag="LSX49_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HBL7169739.1"
                     /translation="MSKVFICAAIPDEQAIKEEGAVAVATAIEAGDERRARAKFHWQF
                     LEHYPAAQDCAYKFLVCEDKPGIPRPALDSWDAEYMQENRWDEESASFVPVETESDPM
                     NVTFDKLAPEVQNAVMVKFDTCENITVDMVISAQELLQEDMATFDGHIVEALMKMPEV
                     NAMYPELKLHAIGWVKHKCKPGAKWPEIQAEMRIWKKRREGERKETGKYTSVVDLARA
                     RANQQYTENSTGKISPVIAAIHREYKQTWKTLDDELAYALWPGDVDAGNIDGSIHRWA
                     KNEVIDNDREDWKRISASMRKQPDALRYDRQTIFGLVRERPIDIHKDPVALNKYITEY
                     LTTKGVFEDEGRNQSATDTLSSPVPETDAVETAIPDNEKTECKVEVEPSVEREGPFYF
                     LFTDKDGEKYGRANKLSGLDKALAAGATEITKEEYFARKNGTYTGSQQNTDASDTTAQ
                     PDLVKVTADEVNKIMQAASISQPDANKLLAASRGEFVEGISDPNDPKWVKGIETRDSV
                     HQNQSETEQYDQKAEQNSQNALQNEPETKQPEPVVQQEEEKVCTACNQTGGGNCPDCG
                     AVMGDATYQETFNEESQDEAREKDPEEIENAGLPNKECTEGDQHANDNNEIGETANPL
                     IKVNSHRKSTSTSRLWHHLMIDLETMGKNPDAPIISIDAIFFDPQTGDMGPEFSKTID
                     LETAGGVIDRDVIKRWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQVWG
                     NGANFENTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERHNA
                     LDDARYQAKYVSVIWQKLIPNQADF"
     gene            complement(7461..7652)
                     /locus_tag="LSX49_003370"
     CDS             complement(7461..7652)
                     /locus_tag="LSX49_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HBL7169740.1"
                     /translation="MNTAFALVLTVFLVSGEPVDIAVSVHRTMQECVTAATEQKIPGN
                     CYPVDKVIHQDNNEIPAGL"
     gene            complement(7649..7837)
                     /locus_tag="LSX49_003371"
     CDS             complement(7649..7837)
                     /locus_tag="LSX49_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HBL7169741.1"
                     /translation="METLLPNVNTSEGCFEIGVNISNPVFTEDAINKRKHERELLNKI
                     CILSMLARLRPIQKGCWQ"
     gene            complement(8403..8621)
                     /locus_tag="LSX49_003372"
     CDS             complement(8403..8621)
                     /locus_tag="LSX49_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169742.1"
                     /translation="MQKREPVIIAPDYTDDELYEWMRQKINAAQDLKWANEARTKQAE
                     NLSALEQDITRLEKAAALSIARMVTYPR"
     gene            complement(8781..8936)
                     /locus_tag="LSX49_003373"
     CDS             complement(8781..8936)
                     /locus_tag="LSX49_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HBL7169743.1"
                     /translation="MDTIDLGNSESLVCGVFPNQDGTFTAMTYTKSKTFKTENGARRW
                     LERNSGE"
     gene            complement(9209..9925)
                     /locus_tag="LSX49_003374"
     CDS             complement(9209..9925)
                     /locus_tag="LSX49_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000103684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7169744.1"
                     /translation="MSTIATSLGSNIGYMKNTISERIRNRRKDVGLTQQQVAKAIGIS
                     RVSVTKWENGSSKPDGENLYLLSKLLSKSPEWILYGKDGHDKTDDLRLNQYPYISDNI
                     ARLPVLTWEQAGYWDMSCPVTKIPGIKNWVDVMTKTAENSFLLHVEGDAMTNSNGLPT
                     IPDGSTVLITPCSSNIRELVGKIILIQLEGTPNVTLKKVAIDGPNIYLLSLNPLYKPI
                     ELNGGYTIKGKVSQIHQYLD"
     gene            9975..10190
                     /locus_tag="LSX49_003375"
     CDS             9975..10190
                     /locus_tag="LSX49_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL7169745.1"
                     /translation="MFKDDVLRYFKKKRLVAEALGISHVAVVRWKAVIPKLRAMELDE
                     ITNGELKYNPELYKKQDSTSNEGKNDS"
     gene            10187..10612
                     /locus_tag="LSX49_003376"
     CDS             10187..10612
                     /locus_tag="LSX49_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBL7169746.1"
                     /translation="MKIKHEHIRMAMNAWAHPDGEKVPAAKITKAYFELGMTFPELYD
                     DSHPEALARNTQKIFRWLDKDTPDAVEKMQALLPAIEKAMPPLLVARMRSHSSEYYRE
                     IVERRDRLVKDVDDFVASAVVLYDQMNRGGPAGNAVVMH"
     gene            10635..11597
                     /locus_tag="LSX49_003377"
     CDS             10635..11597
                     /locus_tag="LSX49_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7169747.1"
                     /translation="MSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAIE
                     TIRRQIGARSESTVKSAIAELAKEGWLTKEERKVGGRNVSNIYRLNVEKLEAAAAAAR
                     ESYKPKRKISPAKNDPLTVDPSNIDPSTVDPSNFDGSTVDKKLPIRGPMIDPDPSVLK
                     PDPSDKRSSCPDASQPDPQTAEQDFLTRHPDAVVFSAKKRQWGSQEDLVCAQWIWGRI
                     VSLYEQAASYDGEITRPKEPNWTAWANDVRTMRMLDGRTHRQICEMFGRLQRDSFWVK
                     NIMSPAKLREKWDELVIRLGRSPAQRCVNHISEPDTEIPPGFRG"
     gene            11604..12350
                     /locus_tag="LSX49_003378"
     CDS             11604..12350
                     /locus_tag="LSX49_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL7169748.1"
                     /translation="MKNIAAVGVLERIRRLAPQGSVPPYRTVEEWREWQLAEGRKRSE
                     EINRQNRQLRVEKILNRSGIQPLHSKCSFANYQVQNDGQKYALSQAKSIADELMTGCT
                     NFVFSGKTGTGKNHLAAAMGNRLMVKGRSVIIVTVSDVMSVLHDSYDNGKSGEKFLQE
                     LCGVDLLVLDEIGVQRETKNEQVVLHQIIDRRTASLCSVGMLTNLNHAAMSTLLGERI
                     MDRMTMNGGRWVTFNWDSWRPNVSNMRVVK"
     gene            12372..13142
                     /locus_tag="LSX49_003379"
     CDS             12372..13142
                     /locus_tag="LSX49_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HBL7169749.1"
                     /translation="METVSDALKALKKASSHVVAARLGISREEAVNELWELKRKGVVD
                     KTGHTWFLAGEGESRVTEERPVKSEAQDMLTGEVEQKVTADMMIEFIGQDGAKTCEEL
                     AGKFGVSTRKVASTLAVVTATGRLARVNQNGKFRYCMPGDNLPAEPKAALVTESDGKA
                     FPQPAGAALPVREAATQEEIKTETVADIVQPLPSFTETQADELIFPSLRRANLALRRA
                     KSDVQKWERVCAALRELNKHRDIVRQITDSSRRVVSEK"
     gene            13158..13583
                     /locus_tag="LSX49_003380"
     CDS             13158..13583
                     /locus_tag="LSX49_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HBL7169750.1"
                     /translation="MAKVFTQEEREKIKGQVVELVRLSGRETLRQLEAKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKVKKPAVVDPDLIWSLPDG
                     EIRRYDRRLNIICRECRKSEAMQRVLAFYQGNVRYFRRY"
     gene            13758..14423
                     /locus_tag="LSX49_003381"
     CDS             13758..14423
                     /locus_tag="LSX49_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBL7169751.1"
                     /translation="MTIADFKRPKLELPNGANKLLLHSCCAPCSGEVMEALQASGIDY
                     TIFFYNPNIHPQKEYLIRKDENIRFAEQHGVPFIDADYDTDNWFERAKGMEWEPERGI
                     RCTMCFDMRFERTALYAAENGFSVISSSLGISRWKNMQQVNECGRRAVAHYPGMVYWD
                     YNWRKQGGSSRMIEISKREKFYQQEYCGCVYSLRDTNLHRKSQGRPLIKIGQLHYGKE
                     EKE"
     gene            14661..14816
                     /gene="hokD"
                     /locus_tag="LSX49_003382"
     CDS             14661..14816
                     /gene="hokD"
                     /locus_tag="LSX49_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HBL7169752.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRLRTGQTEVAVF
                     TAYEPEE"
     gene            14984..15256
                     /locus_tag="LSX49_003383"
     CDS             14984..15256
                     /locus_tag="LSX49_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169753.1"
                     /translation="MAHKTKFHNSDTDLAIRHGRRSHAFKTDWYQHPPCTEEQAEWLI
                     HNYRRRGYEIKKALSLDYRHWIISVRLPYSERPPRPSRTFQQRIWR"
     gene            15258..16313
                     /locus_tag="LSX49_003384"
     CDS             15258..16313
                     /locus_tag="LSX49_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HBL7169754.1"
                     /translation="MRVLLRPVLVPELGLVIVKPGRESMPVFHNTRVLVEPEPKSMRN
                     LPSGVVPAVRQPLAEDKSLLPFFSDERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SETVIHRYGTGAMVLCWHCDNQLRDQTSESLGQLAHQNLFAWMIDVIRHAMNGSQERE
                     LSLAELSWWAVRNQVADALPEAVLRRSLGLRAEKIRSMYRESDIVPGEQTATSILKQR
                     TKNLAPLPHAHQQNPPQEKTVVSIAVDPESPAQYLQRQKSQREEMPVYTRWVKTQKCM
                     TCGNQADDPHHIIGHGLGGMGTKADDLFVIPLCRKCHSELHAGVKDFEEKHGSQLLLL
                     IRFLMHARNSGVLKWKA"
     gene            16314..16694
                     /locus_tag="LSX49_003385"
     CDS             16314..16694
                     /locus_tag="LSX49_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBL7169755.1"
                     /translation="MTERIEFVLPYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVR
                     QQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDALTHAGLLMDDEQFDEINIVR
                     GQPVSGGRLGVKIYPIMHEEQVKK"
     gene            16691..17512
                     /locus_tag="LSX49_003386"
     CDS             16691..17512
                     /locus_tag="LSX49_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HBL7169756.1"
                     /translation="MKLEDLPKYYSPKSPGLTDASASTSKDALSITDVMAAQGMTQNR
                     AEMGFSAFLGKMGISMNDRARATELLADYALSRCDRVAALRKLPAEIKPVVMRIMASY
                     AFEDYARSAASKKQCPCCRGEKFIEGEVFTNKVQYPDGKPPVWAKCTKGVYPSYWEEW
                     KKIREVVKVSCPECKGKGEISTACKDCRGRGVAIHREESVKRGMPVIRDCQRCGGRGC
                     ERLPSTEAFNAICKVTSAITLDTWKKSVKRFYDTLVVRFDIEEAWAERQLKRVTR"
     gene            17739..17936
                     /locus_tag="LSX49_003387"
     CDS             17739..17936
                     /locus_tag="LSX49_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBL7169757.1"
                     /translation="MLKQQDMTETARVVFNELSVTEPATAGEIAQNTYLSRERCQLIL
                     TQLVMAGLADYQFGCYRRLPQ"
     gene            18088..19137
                     /locus_tag="LSX49_003388"
     CDS             18088..19137
                     /locus_tag="LSX49_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBL7169758.1"
                     /translation="MANTVKISSCELINADCLEFIRSLPENSVDLIVTDPPYFKVKPE
                     GWDNQWKGDDDYLKWLDQCLAQFWRVLKPAGSLYLFCGHRLASDIEIMMRERFSVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERILFAEHYQGPYRPKDAGYAAKGSALKQHVMA
                     PLISYFRDARAALGITAKQIADATGKKNMVSHWFSASQWQLPNESDYLKLQSLFARVA
                     EEKHQRGELEKPHHQLVDTYTSLNRQYVELQSEYKHLRRYFGVTAQVPYTDVWTHKPV
                     QFYPGKHPCEKPAEMLQQIISASSRPGDLVADFFMGSGSTVKAALALGRRAIGVELET
                     GRFEQTVREVQGLIV"
     gene            19187..19262
                     /locus_tag="LSX49_003389"
     tRNA            19187..19262
                     /locus_tag="LSX49_003389"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19220..19222,aa:Ile,seq:cat)
     gene            19363..19439
                     /locus_tag="LSX49_003390"
     tRNA            19363..19439
                     /locus_tag="LSX49_003390"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19397..19399,aa:Arg,seq:tct)
     gene            19939..20070
                     /locus_tag="LSX49_003391"
     CDS             19939..20070
                     /locus_tag="LSX49_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HBL7169759.1"
                     /translation="MIAYCFCEWHCCSRIMSVLADGVLVAGVVVVAFPLLKKKTPDC"
     gene            complement(20351..20686)
                     /gene="iraM"
                     /locus_tag="LSX49_003392"
     CDS             complement(20351..20686)
                     /gene="iraM"
                     /locus_tag="LSX49_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HBL7169760.1"
                     /translation="MKWIVIDTVIQPSCGISFSVIWSKIKLIIWYQSDAFLPPESIFT
                     LTHTGIMLNNKVLPVTIYNVVPFNKTFWNLIKNSQECPTNTDNVLNECFNNRCTLQIC
                     PYGLKQQSP"
     gene            20947..>22262
                     /locus_tag="LSX49_003393"
     CDS             20947..>22262
                     /locus_tag="LSX49_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HBL7169761.1"
                     /translation="MAFKHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLM
                     QAIAAEGDVVVSGATEPEWYYVIVLAGQSNAMAYGEGLPLPDSYDAPHPRIKQLARRN
                     TVTPGGEVCVFNDIIPADHCLHDVQDMSTINHPRADLSKGQYGCVGQGLHIAKKLLPY
                     IPNNAGILLVPCCRGGSAFTQGTEGTFSESTGASQDSARWGVGKPLYQDLLFRTKAAL
                     QKNPKNVLLAICWMQGEFDMTNASYAQQPAAFLAMVQQFRADLAGLAAQCHGGSPASV
                     PWICGDTTYAWKQEHGTQYEVVYGAYKGKESQQIYFVPFMTDGSGVNTPTNNPSEDPD
                     IAGSGYYGSASRTNKNWVSSNRPTHFSSWARRGIIPDRMATAILNVAGRTLAFISGKA
                     PEIKPSPGGDTPSGPSEDASVRTISLLPTAGDAAAQGWSIKNGGIQ"
BASE COUNT         5625 a         5137 c         5753 g         5747 t
ORIGIN      
        1 ctgtcacgat ggttgcgcct gctgatcttg aaccgccaca agccgttcaa ccaccaccgg
       61 agccggtggt agagccagaa ccggaacctg agccgatccc tgaaccgcca aaagaagctc
      121 cggtggtcat tgaaaagccg aagccgaaac caaagccaaa accgaagccg gtgaaaaagg
      181 tggagcagcc aaaacgcgat gtcaaacccg tagagtcgcg tccggcatca ccgtttgaaa
      241 atacggcacc cgcgcgcccg acatcaagta cggcaacggc tgcaaccagc aagccggtta
      301 ccagtgtggc ttcaggacca cgcgcattaa gccgtaatca gccgcagtat ccggcacgag
      361 cacaggcatt gcgcattgaa gggcaggtta aagttaaatt tgatgtcacg ccagatggtc
      421 gcgtggataa cgtacaaatc ctctcagcca agcctgcgaa catgtttgag cgtgaagtga
      481 aaaatgcgat gcgcagatgg cgttatgagc cgggtaagcc aggcagtggg attgtggtga
      541 atatcctgtt taaaattaac ggcactaccg aaattcagta agcataaagt caaaagcctc
      601 cgaccggagg cttttgatta ttactcaacg ggtaaggcgc gaggttttcc ttcgggatca
      661 accgcgacat acttaaataa tgcttctgtt gctttatagc gttgcccgat tggttctgac
      721 gccacttttt tcacccacac ttcaatatta atgctgactg atgtcgtccc tttctggaca
      781 cagcgtgcat agcagcacac cacatcgccg accgcaaccg gccgtaagaa agtcattcct
      841 tcaacccgca cggtcactac acgaccgtgg gcaatttctt tcgccagaat agcgccgcca
      901 atatccattt gtgacattaa ccaaccacca aagatgtcac cattggcatt ggtatcggcg
      961 ggcatggcta aagtacgtaa aacaagatcg ccctgaggga cgttatgtgc tgtagacatg
     1021 gtaaaaccga cttaaaagga aaatcacagg cgcgatgcta ctatgatttt cctgaggaga
     1081 acagaggaga tacagcgcca gccccgaagg actggcagtc tggttaggat ttatcttcct
     1141 gcggcatgtg gcggtagata tagataccgc ttaacaatgt gaagattaag gtaagggcgg
     1201 tcaggccaaa gactttaaag ttgacccaaa tattttgcgg cagccagaat gcgatgtaga
     1261 tgtttgccag gccgcaaagg ataaagaaaa cagcccaggc cagattcagc ttcgaccata
     1321 ccgattgcgg cagggtgagt tctttaccca gcatccgctg aattagcggc tttttcatca
     1381 cccattgact gactaacagg gcacccgcaa acagggcata aatgacagta accttccatt
     1441 taataaactc atcattgtga aagaacagcg tcaagccacc gaagacgacc accagaacaa
     1501 aagtgatcag ggccatcttc tcaaccttac gaaagcgaac ccagctatag ataagcacaa
     1561 tcgccgtggc gacgatcagc gccgcagtag ccgcatagat gtcataaatc ttgtaaaacg
     1621 cgaaaaagac aaccagcggt aaaaaatcaa gaaactgctt cattttatga ttccgtaatc
     1681 aaatgcttaa ggttattggc gaatcaacat atacaggcgg aacagataga tgagcaatac
     1741 ggctgaaatc aggttgctca aggtgttcgc cagtacggca ccaatttccg gggttaatgc
     1801 ggcaaaagaa gaggcaaaaa gcagcaacag tgtttttgcc agcaaccagc tcagtactgc
     1861 gggtgccacc agacgcatat tcgcccatgt cagccgcata ctgctacgca tcgaggcaaa
     1921 aacgcccatt ttgtcctgta ccagcatcac cggtgccaga gccagtaaaa tggccatgat
     1981 aattcccgga acgaccacca gcatgatgcc aatctgtact aaaagggtag tcagaaaaat
     2041 cagaataaat aactttggca atatcggcgc actggcacca atagctcgca gcgcactgac
     2101 tctctgaccc gcagacacca gctggataat taatattacg cccccggcga gaatggcgtt
     2161 accgattaat cctgaaaaag tggacgccgc tgaagcctgc agcaaaattt gttgctgttc
     2221 cggtgacata ttctgaacca ggtcgaacaa cccactactg ccgctaacgg gtacgccgtc
     2281 attgagctgc gcaagctgtg catcactggg tgagaaaaca tgccctaaca ccactgtgat
     2341 aaacgcacat agcaacgata ccaacagaat ggtcataaat tgattacgga agaaatttcc
     2401 ggtgtcacgg tatacggact gcgccgtgat agacatgcac tctccttgag ttttatgcag
     2461 gtgttaatta gcgggcaatt gtaccctggt taagccccgg gtggcagcat caggtcttgt
     2521 atggaaaagc atatctttgt aaagcggagg taattgctgg ccttcaggcg tgggtaaacc
     2581 gctgcaagtg gcgagcgagt taatatttgc gtagcgaaat atataaaaat tgatttaaat
     2641 cacattaacc aggattttca atgcaacttc taaattaatc tagatcaata aagggtgaat
     2701 taccatatgt aatgtgatct gtgtaggatc atttgttacc ccaatgtggg tatattcgtc
     2761 acgtttttat aaccataacg acggagcgga tatgaaaaag ttaacagtgg cggctttggc
     2821 agtaacaact cttctctctg gcagtgcctt tgcgcatgaa gcaggcgaat tttttatgcg
     2881 tgctggttct gcaaccgtac gtccaacaga aggtgctggt ggtacgttag gaagtttggg
     2941 tggattcagc gtgaccaata acactcaact gggcctgacg tttacttata tggcgaccga
     3001 caacattggt gtggaattac tggcggcatc gccgtttcgt cataaagttg gcacagccac
     3061 aaccggggat attgcgacag tccatcattt accgccaaca ctgatggcac aatggtattt
     3121 tggcgattct ggcagtaaat tccgtcctta cattggtgcg ggtattaact acaccacctt
     3181 ttttaataat gacttcaatg acaccggtga aggtcttggt ttatctgacc ttagtctgaa
     3241 ggattcatgg ggcgtggcgg ggcaagtagg cctggattat ctcatcaacc gtgactggtt
     3301 gctgaatatg tcagtctggt acatggatat cgataccacg gctaagtaca aatctggtgt
     3361 tactaccgta aaagactcgg tacgactgga tccgtgggtg tttatgttct ccgcaggata
     3421 tcgtttttaa ttttctctgc aaaacctctg caaaacccct ctgcaaaact ggtcatcaaa
     3481 tgaccagttt tttccattcc ttaccgcgtg cgtcgttgta aatatcggtc attttttgat
     3541 tcgaatggcc cagcaaaatt ttggtatcaa ccccctgctc tctgaacaat cgctctgata
     3601 aagatctctg ctcatggaaa gagggtgggg tgccattagc acgccagttg taatccacag
     3661 aatcccgggc ttttttaaat gcaacggtta atgttgctgg cttaaccatc ccgccgcgct
     3721 tagctgtccc tttcgcgtga tggtggtgca atagccacgg actaagaacg caatcgcggc
     3781 aggatgacac cacatcatct agggtgagat ttaatttatc gcaacgcaga gccagaggga
     3841 tggcaatccg ggttcctgtt ttttgctgtt cgacatgaag ataaccatcc cggatatccg
     3901 aaaattgcat tttgcaaata tctgaaaggc gctggcctgt catcagtgcc agcagcatac
     3961 cgcgctgtaa aaagtaacca tccttttccg ctgcgttata aatcatcatc cactcatcaa
     4021 aagtcagtcg ctgtcttgat atccgcacct gcggtttttt tgccgattct gcagggttaa
     4081 agcctggcgg gacatcgccc gtttgctgag cttcccggaa aacatcgatc agtaccttcc
     4141 tgaaaatttg tcccattctg ttatgtcctc tggccttgta ctcttccagt actgatacca
     4201 catcttttac ggttatggca tctaacggtc tggtgccaaa acgttcatca aataccctga
     4261 gaggggccgc tttctgtttc agcgtgttga gtttgatctc gccgttttca tatctttcct
     4321 gttgaatttt tctgtaatta ttcagaaaaa tggtaacggt tgatgaaccg ccggtatcac
     4381 taataatttt ctcctgcaga ctgagcattt gttccatttg ctgccgggca agacggctgt
     4441 tcgcttctgc tgcaatagtt tctgccagtt tctggtcaat actgccgaga ccgtgatttt
     4501 tgcctgttat gggatgcctg taacgccagt aaactttgtt atttcttttg tcaaaatacg
     4561 gagataatcc cggaacattg gttttatatt ttcgcgggcg cgccatcttc cagtatcctc
     4621 ttcaaagcag ggtgatctgt ggcgatcacc tccggcttgt ttaccattcc gacaaagcga
     4681 gcttgcggat ccactcgcca gcgtcttcca acttttttgg ggagaggaaa tatcattccg
     4741 gctttagcgt atttacttaa cgtactcgga gttgggaccg gttcactgaa ttcctctttt
     4801 gcccactcag tgagcagaat aagtcttgcc atgagcgtcg ttcgctaatc atggtcgccg
     4861 ccactatagc tggtgggcaa cgaccggggt tgaacattaa aaatcagcct gattcgggat
     4921 cagtttttgc cagataactg aaacgtattt tgcctggtaa cgggcgtcat caagtgcatt
     4981 atggcgctca ccttcgaatg gaatagccgt tctggcatcg aagtctatgg ctttccccag
     5041 ctcaacgatt gtgcgtacat cgcgatcgtt gtagtaacgc catgggcagg ggatcccctg
     5101 ccgttcgtat gaacggcgca aaatcgtgtt ttcgaagttg gctccatttc cccagacctg
     5161 aacaaaaaat tcaccggagt tttcgtcgat aaattcccgc aattgtaaca gtgcatcatc
     5221 taacgggatt tcatcggtca taatggcaga ctgcgcttca cgtgattgct tcagccacct
     5281 tttaatgacg tcacgatcaa tgactccgcc agcagtttcc agatcgatag tcttactaaa
     5341 ttccggtccc atatctccgg tttgcggatc gaaaaatatt gcatctattg agataatcgg
     5401 ggcatcagga ttttttccca tggtttcaag gtcaatcatc agatggtgcc acaacctgct
     5461 ggtggatgtg cttttacgat gactgttcac cttaattaag ggatttgctg tctcgcctat
     5521 ttcattattg tcattggcat gttgatcgcc ttcggtgcac tccttgttcg ggagtccggc
     5581 attttctatt tcctctggat ctttttcccg ggcttcatcc tggctttctt cgttgaatgt
     5641 ctcctggtag gttgcgtcac ccatcactgc gccacaatca gggcagttac caccaccagt
     5701 ctgattgcat gcggtacaaa ctttttcctc ttcctgttgc acgactggtt caggttgttt
     5761 cgtttctggc tcgttttgta acgcattttg gctgttttgt tccgcttttt ggtcgtactg
     5821 ttccgtttct gactggttct ggtgcacaga atcgcgggtt tcaatcccct tcacccattt
     5881 cggatcattc gggtcgctaa tcccttcaac aaattcacca cgtgatgcag cgagcaactt
     5941 attagcgtca ggctggctga tactggctgc ctgcataatt ttgtttactt cgtcagcggt
     6001 aacttttacc aggtctggtt gtgcggtcgt gtcagatgca tcagtatttt gttgtgaacc
     6061 tgtgtatgtg ccgtttttgc gggcaaaata ttcttctttc gtgatttcag ttgccccggc
     6121 agccagcgcc ttatccagac cagaaagttt gtttgcgcga ccgtattttt cgccatcctt
     6181 gtcggtgaag aggaagtaga acggcccctc acgctctaca gatggttcga cttccacttt
     6241 gcattcggtt ttttcgttgt ccggaattgc cgtttccact gcatcagttt ctggtactgg
     6301 cgacgagaga gtatcagttg cgctctgatt tcttccttca tcttcaaaca cgccctttgt
     6361 agtcaggtat tcagtaatgt atttgttcag tgccacaggg tctttgtgaa tgtcgatcgg
     6421 acgttcacgg acaaggccaa aaatagtctg gcggtcgtag cgaagggcat caggctgttt
     6481 gcgcattgat gccgagatac gcttccagtc ttcgcggtcg ttgtcgataa cttcattttt
     6541 tgcccagcga tggatgctgc cgtcaatgtt tccggcatcc acatcaccag gccagagagc
     6601 gtaggccagt tcgtcatcca gtgttttcca tgtctgcttg tattcgcgat gaatggcagc
     6661 aatgaccggg ctgatttttc ctgttgaatt ttcagtgtac tgttgattgg ctctggcgcg
     6721 ggcgagatca acaacagacg tgtattttcc ggtttccttg cgttcacctt cacgacgttt
     6781 tttccagatg cgcatctctg cctgaatttc gggccatttg gcaccaggct tacatttatg
     6841 cttaacccac ccgatggcat gcagcttaag ctccggatac atggcgttaa cttctggcat
     6901 tttcatcaac gcttcaacga tatgtccgtc gaatgttgcc atgtcttcct gcaacaattc
     6961 ctgtgcgcta ataaccatat caacggtgat gttttcacat gtgtcgaact taaccatgac
     7021 agcgttctgt acttcagggg ccagcttgtc aaaagtgacg ttcatcggat cggattcagt
     7081 ctcaaccggg acaaaggaag cagactcctc atcccagcgg ttttcctgca tatattcagc
     7141 atcccaggaa tcgagggcag ggcggggtat accgggttta tcctcgcaga caagaaattt
     7201 ataagcgcag tcctgagcag ccggataatg ttccaggaat tgccagtgaa attttgcgcg
     7261 ggcgcgacgt tcatcaccgg cttcaatggc agtggctaca gcgacggcac cttcttcctt
     7321 tattgcctgt tcgtccggaa tggcggcgca aataaagact ttactcattt tgttttacct
     7381 cattacagat ttaagggtga acaaatccct gccattgctg gcatataaga atgaaaccgg
     7441 atatttatta cggaactgtt ttaaagacct gccgggattt cgttattatc ctggtgaata
     7501 actttatcga ccgggtaaca gttaccggga attttctgtt cggttgctgc agtcacacac
     7561 tcctgcattg tcctgtgaac actgactgca atatcaactg gctctccgga aacaagaaaa
     7621 actgtcagaa caagtgcaaa tgctgtattc attgccagca tcctttttgt atcggacgta
     7681 aacgggccag cattgaaaga atgcatattt tatttaatag ctcccgttcg tgttttctct
     7741 tgttaatggc atcttcagta aatacagggt tactgatatt gacaccaatt tcaaaacaac
     7801 cttcagacgt attaacgttt ggtaataacg tttccattat cgcgtcctca acaatgaatt
     7861 ttgtgatgcg gtgcctggtg cctccaggtg acgttaacca gttaacaatt aacgccggat
     7921 acagagaatc cacccataac actgtttttg gttttaactg ttccgcgtgc gctcagccgc
     7981 attcaccaca tcacaaaatt cactttaaaa agggcggcag agcagtcacg gagtaaaact
     8041 gataccgcca aacgtcacca gaaaattgat aacagagggc gttgcagcgg agttgtcact
     8101 taagcgtatg gtcaacctga caacccggtg tcctcaacgg aggaaggaat aaccccgcca
     8161 tacttaccgc cgcgccattt cgcggagtgc cacaaccgga agcgcacggt cgaactaaat
     8221 ttaacgacac cgtacagaga gaccaatttc gccgtgcgct ttcgctttat gccctgactt
     8281 ttcagggaca tatcctttca gtaaactgtc agtgccggat gttcacccgt gtccggcgca
     8341 cgcactccac ctgacccgtg gagaactcct taattaccaa ccttagcttc gttggttagc
     8401 tattaacgcg ggtatgtaac cattctggca atgcttaatg ccgctgcttt ttccagcctg
     8461 gtgatatcct gctccagagc ggacagattt tcagcctgct tagtcctggc ttcattggcc
     8521 catttcagat cctgcgctgc attaattttc tggcgcatcc actcataaag ttcatcatcg
     8581 gtatagtctg gcgcgatgat gacgggttct cgtttctgca tactgattcc tcgcggtgct
     8641 gcttcgctta tcagccgtta gattttgccg agctggaaag cgcctgttta aactcactga
     8701 agctgagagc ttcttcgcct tcggcaaggc cttcgaagta ttcttcgtaa gccttttcca
     8761 tgattgtgtc gaaatccata tcactcacct gagtttcttt ccagccagcg acgggcacca
     8821 ttttcggttt taaacgtttt gcttttggta tacgtcattg cggtgaacgt gccgtcctgg
     8881 ttggggaaca cgccacatac cagagattcg ctgttgccaa gatcgatagt atccatgctg
     8941 acctcatttc cccttaacgc cgggggagcg gaacaaaaac ctgctgcata gttattaaag
     9001 ttgaaccctg ccgtcatgtt cttacgcctc gggctggcta cttaccccct gaccactgct
     9061 tggtaactcg aagtattgcc cggcgttctg tggggcgggg tgggttggta tgttgttaag
     9121 gtaacaagag ttacctttcg agtcaataca atgttgcaaa aggtacattt gagggcataa
     9181 aaaacccgca atgaatgcgg gttctgactc agtctaagta ttgatgtatt tgtgaaactt
     9241 tacctttaat ggtgtaacca ccattcagtt cgatgggttt gtaaagcgga ttcagtgaca
     9301 acagatagat gtttggtccg tcaatcgcaa ctttttttag tgttacgttt ggcgttcctt
     9361 ccaattggat taagattatt tttcccacca gttctctaat gttacttgag catggtgtga
     9421 tcagcacggt agatccgtcg gggatggttg ggaggccgtt agagtttgtc atcgcatctc
     9481 cctcaacatg caataaaaaa gagttttcag cggtttttgt catgacatca acccagttct
     9541 taataccagg aatcttggtt actggacaac tcatatccca ataaccagcc tgttcccacg
     9601 ttaaaacggg caaccgggcg atgttgtcac taatgtaagg gtactgattc agacgcagat
     9661 catcggtttt atcgtgaccg tcctttccat aaagaatcca ttcaggagat ttggaaagca
     9721 attttgacag tagatacaaa ttctcaccgt caggttttga agagccattt tcccattttg
     9781 ttacggatac acgagatatg ccgattgctt tcgcaacctg ctgttgggtt aatccaacgt
     9841 cttttcgacg attccgaata cgttcgctga tagtgttttt catgtaacca atgttactac
     9901 caagtgatgt tgctatggtt gacattgtta tgtaactatt gttacccttc tgctcgaaat
     9961 aacaggagag ttttatgttc aaagatgatg ttctgcgcta tttcaaaaaa aagcgactag
    10021 tagctgaggc tcttggaatt tcacatgtgg ctgttgtgcg gtggaaagca gttattccca
    10081 aacttcgcgc aatggaactg gatgaaatta ctaacggtga attgaaatac aacccagaac
    10141 tttacaagaa gcaggatagc acctcgaacg aaggaaagaa tgattcatga aaatcaagca
    10201 tgaacacatc cgcatggcga tgaatgcctg ggcgcatccg gacggcgaaa aagtgccggc
    10261 tgcgaaaatt accaaagcgt atttcgagct gggaatgacg ttcccggaac tgtatgacga
    10321 cagccatccg gaagccctgg cccgtaatac ccagaaaatt ttccgttggc tggataaaga
    10381 cacccctgat gctgttgaaa aaatgcaggc tctgttaccg gcgatcgaaa aggcgatgcc
    10441 gcctttgctg gtggcccgta tgcgcagcca cagttctgaa tattaccgtg agatcgtcga
    10501 acggcgggat cggctggtga aggatgtcga tgattttgtt gcgtcagcgg ttgttttgta
    10561 tgaccagatg aatcgcggcg gcccggcagg gaatgctgtg gtgatgcact aaaagcacgg
    10621 tgttcggggg ttttatgagc agcaagcttc atggtcttgt ctgggaaggg tgcgccttca
    10681 ccggcatgat cttatccagg gtggcggtta tggcccgtct tgcagactac agcaatgacg
    10741 agggcgtgtc atggcctgcc attgaaacta tccggcgtca gatcggtgca agaagtgaat
    10801 ccacagtgaa atcggctatt gcagaactgg cgaaagaggg ctggctgacg aaggaagagc
    10861 gtaaggtcgg tgggcgtaat gtaagcaata tctatcggct taatgtggaa aaactcgaag
    10921 cagctgcggc ggcggcgcgt gagtcatata aaccgaaaag aaaaattagc ccggcaaaaa
    10981 atgacccgtt aacagttgac ccgtcaaata ttgacccctc aacggttgac ccgtcaaatt
    11041 ttgatggatc aactgttgat aaaaaactgc cgattagggg gccgatgatt gaccccgatc
    11101 cgtcagtatt aaaacctgat ccgtcagata aaagatcttc ttgtccggac gcttcgcaac
    11161 cggacccgca gacggctgaa caggattttt taacccgaca ccctgacgcg gttgtgttca
    11221 gtgcgaaaaa acgccagtgg ggaagtcagg aagatttggt gtgcgcacag tggatctggg
    11281 gacgaatcgt gagtctttac gagcaggcgg ccagctatga tggcgagatc actagaccga
    11341 aagaacccaa ctggacagca tgggccaatg acgttcgcac aatgcggatg ctggatggca
    11401 gaactcacag acaaatttgt gaaatgtttg ggcgtctcca gcgggattcg ttctgggtaa
    11461 aaaacatcat gagtccggca aaactccggg aaaaatggga tgaactggtt atccgcctgg
    11521 ggcgttcgcc tgcgcagcgt tgcgtgaatc acatttctga accggacact gaaataccgc
    11581 cgggattcag ggggtgacgt gtcatgaaaa acattgcggc agttggggtt cttgaacgta
    11641 ttcgcagact tgcaccacag gggtcggttc caccgtaccg gacggtggag gagtggcggg
    11701 aatggcaact tgctgaagga cgaaaacgca gcgaggagat taaccgccag aatcgccagt
    11761 tgcgggtgga aaaaatcctg aatcgttcgg gcatccagcc tctgcacagc aaatgctcgt
    11821 ttgcaaatta tcaggtgcag aacgacgggc aaaaatacgc gctgagccag gccaaatcca
    11881 tagctgacga actgatgacc gggtgcacga attttgtgtt cagcggtaaa accggcaccg
    11941 ggaaaaatca ccttgcagcg gcgatgggca accggctgat ggtgaagggg cgcagcgtga
    12001 ttatcgtcac cgtgtctgac gtcatgagcg tgttgcatga cagctacgac aacggcaaat
    12061 ccggggaaaa atttttacag gagctttgcg gggttgattt gctggtcctg gatgaaatag
    12121 gcgttcagcg ggagacgaaa aacgagcagg tggtattgca ccagataatt gatcgccgga
    12181 cagcatcact gtgcagtgtc gggatgttaa caaacctgaa tcatgccgca atgagtacgc
    12241 ttcttggtga gaggattatg gaccgcatga ccatgaacgg tggtcgatgg gtgacgttta
    12301 actgggatag ctggcgtcca aatgtcagca atatgagggt tgtgaagtaa ttttgtccgg
    12361 aggaaatttt aatggaaacc gtatctgacg cactgaaagc actgaaaaaa gcctcttcac
    12421 atgtggtggc agctcgcctt ggaatcagtc gtgaagaggc tgtcaacgag ctgtgggaac
    12481 tcaaaagaaa aggcgtcgtt gataaaactg gtcacacctg gtttctggct ggcgaaggtg
    12541 aatcccgggt aaccgaagag cggccagtaa aatctgaagc acaggatatg ctgaccgggg
    12601 aggtcgaaca aaaagttacc gcagacatga tgattgagtt tatcggtcag gatggggcta
    12661 aaacgtgtga ggaactggcg ggtaagttcg gtgtcagtac tcgcaaggtt gcttccacgc
    12721 tggcggtggt aaccgcaacg gggcggctgg cacgcgttaa tcagaacggt aaatttcgtt
    12781 actgcatgcc gggcgataat ttaccagcag agccgaaagc cgcgctggta acggaaagtg
    12841 atggtaaggc ctttcctcag ccagcaggtg ctgcgttacc agtccgggaa gccgcaacac
    12901 aggaagaaat taaaacagaa actgtggcgg acattgtgca gccgttgcca tcgtttaccg
    12961 aaacgcaagc agatgagctg atttttccgt cccttcgcag ggcaaacctg gcgctgcgca
    13021 gggcgaaaag tgatgttcag aagtgggagc gagtctgcgc cgcgctgcgg gagctgaaca
    13081 agcaccggga tattgttcga cagattactg attcttcccg ccgtgttgta tcggaaaagt
    13141 gattgccgga ggcgcttatg gcaaaagtat ttacacaaga agagcgggaa aaaattaaag
    13201 ggcaggttgt tgaacttgta cgtctgagcg gtcgcgagac gttgcggcaa ctggaagcca
    13261 agacaggtgc gacaagatat ctgatgagtg ttctcgccag agagctggtt gccagtggcg
    13321 atgtatacaa ctctggttac gggttattcc cgtctgaaca ggcgcgtaag gactggcaaa
    13381 atgctcgcaa aaaactctca agggcaaagg tgaagaaacc tgcagtggtt gatccggacc
    13441 ttatctggtc gttaccagac ggcgaaatac gccgctacga caggcgcctg aatataatct
    13501 gtcgcgagtg ccggaagagc gaagctatgc agcgtgtact ggcattttat caaggaaatg
    13561 ttaggtattt tagacgttac tagattaaag agcattagtt cagatgtgaa ttgacatttt
    13621 catggcgcag ggtagagcca gcgtggttgt ccgctttgcg tcaaaaccag atattaccag
    13681 atttagacat atattcccga tagccctgct ctgatgctac actctgtgct attttcatga
    13741 ccccaataaa aatatttatg actattgctg atttcaaacg gcctaaattg gagctcccaa
    13801 acggggcaaa caaactacta ctgcactctt gctgtgctcc atgttccggt gaagtgatgg
    13861 aggcgcttca ggcctcggga atcgactaca ccatcttttt ctacaacccg aacattcatc
    13921 ctcagaaaga gtatttaatt cgtaaggatg aaaatattcg ctttgctgaa caacacggcg
    13981 tgccgtttat cgatgctgat tacgacaccg acaactggtt tgaacgtgcc aaaggaatgg
    14041 aatgggagcc tgagaggggg atccgttgta ccatgtgttt tgacatgcgt tttgagcgga
    14101 cagcgttgta cgctgctgaa aatggtttca gtgtgatcag cagttcactg ggcatttcac
    14161 gctggaaaaa tatgcagcag gttaacgagt gtgggcggcg agctgttgcg cattatccgg
    14221 gtatggtgta ctgggattat aactggcgca agcagggcgg ctcgtcccgt atgattgaaa
    14281 tcagcaagcg cgaaaaattc tatcagcagg aatattgtgg ctgtgtgtat tctctgcgcg
    14341 ataccaatct acaccgcaaa tctcagggac gccctcttat caaaattggc caactccact
    14401 acggaaaaga agagaaggag tgattttatg gatcaccttt ctgattgatt tcatattggc
    14461 gaggtgacgt gagttaagta gaatggctgc gggtgcttga ggctatctgt ctcaggcatg
    14521 aacactgaaa ggcagataga gaaaagcccc agttaacatt tcgcgtcctg caagacgctt
    14581 aacattaatc tgaggcccaa tctatgtctc acaaatgtag gttagcctct tacgtgccga
    14641 aaggcaaggg gaagcaggct atgaagcagc aaaaggcgat gttaatcgcc ctgatcgtca
    14701 tctgtttaac cgtcatagtg acggcactgg taacgaggaa agacctctgc gaggtacgac
    14761 tccgaaccgg ccagacggag gtcgctgtct tcacagctta cgaacctgag gagtaagaga
    14821 cccggcgggg gagaaatccc tcgccacctc tgatgtgtca ggcatcctca acgcacccgc
    14881 acttaacccg gttcggcggg ttttgttttt ttctggcatt ctggtttaca attcgcacgt
    14941 cagcctgaac acctgacacc tgctgcgcca gcagagaaaa cagatggcgc acaaaaccaa
    15001 atttcacaat tctgataccg accttgccat ccggcatggg cggcgttcac acgcatttaa
    15061 aaccgactgg taccaacacc caccatgtac tgaagaacag gccgaatggc taattcataa
    15121 ctaccgcaga cgcggatacg agattaagaa agccctcagc ctcgattatc gtcactggat
    15181 aatctccgtc aggcttcctt actctgaacg cccaccgcgt ccgtcccgca cattccagca
    15241 acgcatctgg aggtaacgtg cgggtattac ttcgacctgt tctggtaccg gaactcgggc
    15301 tggtgatcgt taagccgggc cgtgaatcca tgccggtatt ccacaatacc cgggtactgg
    15361 tggagccgga accgaaaagc atgcgtaatc tgccgtccgg ggtcgttcct gccgttcgcc
    15421 agccgctggc ggaggataaa tcattactgc catttttcag cgacgaacga gtgattcgtg
    15481 ctgctggtgg cgctggcgca ttgtctgact ggttactgcg ccatgttaaa tcctgccagt
    15541 ggccacacgg cgattatcac cacagtgaaa ccgtcattca ccgttatggt accggcgcaa
    15601 tggtgttgtg ctggcactgc gacaaccagc tgcgcgacca gacctccgaa tcactcgggc
    15661 aacttgctca ccaaaacctg tttgcatgga tgattgacgt catacgccat gcaatgaatg
    15721 gctcgcagga acgggaatta tcgctggctg aattatcctg gtgggcggtc cgcaatcagg
    15781 tggcggacgc gctaccggaa gcggtattac gtcgttcgct ggggttgcgt gcggaaaaaa
    15841 tccgctcaat gtaccgtgaa agcgacatcg taccgggaga gcagaccgcc accagcatac
    15901 tgaagcagcg cacaaaaaat cttgcgccgc tgcctcacgc ccaccagcaa aacccgccac
    15961 aggaaaagac ggtggtcagc attgccgttg atccggagtc accggctcag tatctccagc
    16021 gccagaaatc acaacgggaa gagatgcctg tatacacgcg ttgggtaaaa acgcagaaat
    16081 gcatgacgtg tggcaatcag gcagatgatc cgcatcacat cattggtcat ggactgggag
    16141 ggatgggaac aaaggctgat gatttgtttg ttattccgct gtgccgtaaa tgccatagcg
    16201 aactacacgc cggggtaaaa gattttgaag aaaaacacgg cagccagctg ttgttgctga
    16261 ttcgtttttt aatgcacgcg agaaattcgg gtgttctgaa gtggaaagca taaatgactg
    16321 aacgcataga atttgttttg ccttacccgc caacggtgaa cacttactgg cgtcgtcgtg
    16381 gcagcacata ttttgtatca aaagccgggg agcgttatcg ccgggcagtg gcgcttattg
    16441 ttcgccagca gcggctgaaa ttaagcctgt ccggaaggtt ggcaataaaa attattgcag
    16501 aaccaccgga taagcgccgc cgtgatctgg acaatattct gaaagcgccg ctggatgcgc
    16561 tgacgcatgc ggggttgcta atggacgatg agcagtttga tgaaatcaat atcgttcgtg
    16621 gtcagccagt atctggtgga cgtctggggg tgaagattta ccccataatg catgaagagc
    16681 aggtcaaaaa atgaaactgg aagatttacc gaaatactac tccccaaaat cccccggcct
    16741 gactgatgca tcggcctcaa cgtcgaaaga tgcgctgagt atcactgatg tgatggccgc
    16801 gcagggcatg acacagaatc gggctgagat ggggttttct gcgttcctgg ggaaaatggg
    16861 catcagtatg aatgacaggg cgcgggcaac agaattactg gcagattatg cactcagtcg
    16921 gtgcgatcgt gtggcggcgt tgagaaaact tccggcagaa ataaaaccgg tagtgatgcg
    16981 cattatggct tcgtacgctt ttgaggatta tgcccgcagc gcagcgagta aaaagcagtg
    17041 cccctgttgc cgaggggaaa aatttattga aggcgaagtt tttacaaaca aggttcagta
    17101 tccggatggc aagccgccag tatgggcaaa gtgtacgaaa ggtgtgtatc cgtcttactg
    17161 ggaagaatgg aaaaaaattc gggaggtggt gaaagtttct tgtcctgaat gtaaagggaa
    17221 gggggagatt tccactgcct gtaaagactg ccgtgggcgt ggtgtcgcca ttcatcgtga
    17281 agagtcggta aaacgtggta tgcctgttat cagagactgc cagcgttgtg gtggtcgtgg
    17341 ctgtgaaaga ctaccatcaa cggaggcatt taatgccata tgcaaagtga cgagtgctat
    17401 cacgcttgat acgtggaaaa aatcagtgaa acgcttttac gatacgttgg tggttcggtt
    17461 tgacattgaa gaggcatggg cggagcggca gttaaagagg gtaacgcgat agtgttgttg
    17521 atttttcccg aatctgtggt aaatttgctc taacgatggg cgttttatgc ctgacgttag
    17581 aagatttttt acaccccgcc gcctggcggg ttttttatga ctgaaatcgc gtcagtacag
    17641 taaacgcgct ggtggcggtg aatacctgtc tttcagcttg ctggcttttt cgacaagagt
    17701 tattggtgtg tcacgttaac cggaaaaggg aaaaagacat gctgaaacag caggatatga
    17761 cagaaaccgc cagagtggtg tttaatgaat taagcgtcac cgaaccggcg acagccgggg
    17821 agattgcgca gaatacttac ctttcacgcg aacgctgcca gttaatactg acccagctgg
    17881 ttatggcggg tctggcagac tatcagttcg gttgttacag acgccttccg cagtgaaggc
    17941 ttttttattt gtggtaaatg ggcggctggt gggtgttagg ggcacccacc agccatctgc
    18001 tcatgcgttg gggtcacaag caaacctcag gcccatctgc tttgcgcaaa agcggtatga
    18061 gcctatcaga gaagtgctta ttgatctatg gctaatactg taaaaatatc cagttgtgag
    18121 ttaatcaacg ccgactgcct ggaatttatc cggtcgttac ccgaaaattc tgttgacctg
    18181 atagtcacgg acccgccgta ctttaaagtg aagcctgagg gctgggataa ccagtggaag
    18241 ggcgacgatg attacctgaa gtggctggac cagtgtctgg cgcagttctg gcgggtgctg
    18301 aaacctgccg gaagtcttta cctgttctgt ggtcatcgcc tggcatctga tatcgaaatc
    18361 atgatgcgtg aacgcttcag tgtgctgaac catattatct gggcgaagcc gtccggacgc
    18421 tggaacggat gcaacaagga aagcctgcgg gcgtatttcc ccgccacaga gcgcattctg
    18481 ttcgcggaac attatcaggg gccgtatcgt ccgaaagatg ccgggtatgc ggcgaagggc
    18541 agtgcactga aacagcatgt gatggccccg ctgatttctt actttcgtga tgcgcgcgcg
    18601 gccctgggga taacggcaaa acagattgca gatgccacag gaaagaaaaa catggtgtcg
    18661 cactggttca gtgccagtca gtggcagcta ccgaacgaaa gcgattatct gaaattacag
    18721 tcgctgtttg cccgggtggc agaagagaaa catcagcgcg gtgaactgga aaagccccac
    18781 caccagctgg tggatacgta tacgtcactg aaccggcagt atgtggagct gcagagtgaa
    18841 tataagcatc tgcggcggta ttttggtgtg acggcgcagg tgccgtacac ggatgtgtgg
    18901 acacataaac cggtgcagtt ctatcccggg aaacatccgt gcgaaaaacc ggcagaaatg
    18961 ctgcagcaga taatcagcgc aagcagtcgt ccgggtgacc tggttgcaga tttttttatg
    19021 ggctcaggtt caacggtaaa agcggcactg gcgctcgggc gtcgtgcgat tggcgttgag
    19081 ctggagaccg gacgttttga gcagacagtc agggaagttc agggtttaat cgtttgaaac
    19141 ggatgagatt gcagaattaa ttacgcacca ttattattct gctcccggcc ctttagctca
    19201 gtggtgagag cgagcgactc ataatcgcca ggtcgctggt tcaaatccag caagggccac
    19261 catcacaaac cgccattagc ttatcaggaa gagcagacga cacgataaca gggttgttgg
    19321 tgcgggggcg ggtccccgat ggcggtccat tatcggtatt cagcgttgtt agctcagccg
    19381 gacagagcaa ttgccttcta agcaatcggt cactggttcg aatccagtac agcgcgccat
    19441 attcattctt ccagattcct tccggcagag ccttatactg aaatatacct ggctcaggat
    19501 attgttgaaa atattatatg tttgtcaaaa ataaaagttc tgttaagtgt tgattgagtg
    19561 tttgttatac ggtctaatgg ttttttcagc attaaatatt tatcattcat atggtgtggg
    19621 tagagtgaat attgatgagg cgtcggggtg tttcatcctt aggcagcgta ttgatatagt
    19681 caatgcagca cgagcaaagg ccttcagccg tttgacagtt ttgttctgta ctcctgatcg
    19741 tctttcggga agagacgtta ttattctgaa tagtgatgct atacagaggg tttgcgatga
    19801 gttcatggtg gctaattcag aattatttac tcttgttcag gagtacaaca gaatagccag
    19861 gacctgtggt atggatgaac ttcggattac tcatctgggg tagatacata tctggattat
    19921 caccggttac ggtaaaaagt gattgcttac tgtttttgtg aatggcattg ctgcagccgg
    19981 ataatgtcag tgctggctga cggtgtgctg gtggcgggtg tggtggttgt tgctttcccg
    20041 ttgctgaaaa agaaaacgcc agactgttag ccgggtatca gttagcggga gaaattttta
    20101 aatacttcac aattcaggcg gttgattgtt gtctggtttg cggggagttt gttaaaagaa
    20161 actggcatgg tgaatccccc tgtgcggagg ggcaatcagc gagtaggtat atgggataat
    20221 cgcggattca ggtgctggta ctgaattcac cgggaggcac ccggcaccat gcaatggcac
    20281 atagcgccac tctccagccc ctctccggag gggctgttta tattgatttt gtcagatgtg
    20341 agtaaactcc ttatggactt tgttgtttta gtccataagg acatatttgc agagtgcaac
    20401 ggttattaaa gcattcattc aatacgttat ctgtatttgt agggcattcc tggctgtttt
    20461 tgattaaatt ccagaatgtt ttattgaatg gtactacgtt gtaaatggtt acaggtagca
    20521 ctttgttatt gagcatgatg cctgtgtgag tcagtgtaaa tatactttca ggaggtaaga
    20581 aagcatccga ttgataccag attattaatt ttattttact ccatatgact gaaaaagata
    20641 ttccgcatga tggctggata actgtatcaa tcacaatcca cttcatttag tttccttgtt
    20701 tatgccttgc tggtgatgtt ctgaaaagta taaatgatat ttttgattgt aaaccataga
    20761 gcagaattat ttttctgatg ttgtttattg tttatttaaa tgcagggtgg tttatatctc
    20821 gtcttgtagt ttatccatgc atatctgctt gatgatgagg tttttattta aggtatggtt
    20881 ttgtgttttt tctgtattac atgtcaggta ttttaaagaa tcatttttca gatggtggaa
    20941 agaaccatgg catttaaaca ctatgatgtt gtcagggcgg cgtcgccgtc agatcttgcg
    21001 gaaaagctga cacataaact gaaagagggc tggcagccgt ttggtagtcc ggtggccata
    21061 accccttata ccctgatgca ggcgattgca gcagaaggtg atgtggtcgt cagtggtgca
    21121 actgagccgg agtggtacta cgtcatcgta ctggccgggc aatccaatgc catggcttac
    21181 ggtgaagggc ttccgcttcc ggattcatac gatgcgcccc atccgcgcat taagcaactg
    21241 gcccgtcgta acacagtgac tcccggtggt gaagtatgcg tatttaacga catcattcct
    21301 gctgaccatt gtctgcatga tgttcaggat atgagtacga ttaaccatcc ccgggctgac
    21361 ctgagcaaag ggcagtacgg ctgtgtcgga cagggcttac atattgccaa aaaactgctt
    21421 ccgtatatcc ctaataatgc ggggatcctg ctggtaccat gctgtcgtgg tggttcggca
    21481 ttcacccagg gcacggaggg gacattcagc gagtccacgg gggccagtca ggattcggct
    21541 cgctggggag tgggtaagcc gttatatcag gatctgcttt tccgcacgaa ggcagcattg
    21601 cagaaaaacc cgaaaaacgt tttgctggcg atatgctgga tgcaggggga attcgatatg
    21661 acgaatgcca gttacgccca gcagccagca gcatttcttg caatggtaca gcagttccgt
    21721 gctgaccttg ccgggctggc ggcgcagtgt cacggtggaa gtccggcatc agtcccctgg
    21781 atttgtggcg acacgacata cgcgtggaaa caagaacacg gtacgcaata tgaagtggta
    21841 tatggtgcat ataaaggtaa agaatcccag cagatttatt ttgttccctt tatgaccgat
    21901 ggtagcggag ttaatacacc gacaaacaac ccgtcagaag atcctgatat tgccgggtct
    21961 ggttattacg gttcggcatc ccgaacgaac aaaaactggg tatcatcaaa tcgcccgacg
    22021 catttcagct catgggcgcg tcgtggcatt attcccgatc gtatggcaac tgctattctg
    22081 aacgtagccg gtcgcacctt agccttcatt agtggtaagg caccggaaat caaaccctcg
    22141 cccggcggcg acacgccatc ggggccgtct gaagatgcat ccgtacgcac aatctccctg
    22201 ttgccgacag ccggagatgc tgctgcgcag ggctggagca ttaagaatgg cggaattcag
    22261 tt
//
LOCUS       DAFGPF010000080        22144 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFGPF010000080 DAFGPF010000000
VERSION     DAFGPF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22144
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.080"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(56..1246)
                     /gene="bcr"
                     /locus_tag="LSX49_003394"
     CDS             complement(56..1246)
                     /gene="bcr"
                     /locus_tag="LSX49_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HBL7169762.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVACALAQTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILAVAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNILFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCATSSILFCLYASR
                     PKKR"
     gene            complement(1274..1969)
                     /gene="rsuA"
                     /locus_tag="LSX49_003395"
     CDS             complement(1274..1969)
                     /gene="rsuA"
                     /locus_tag="LSX49_003395"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HBL7169763.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            2119..3885
                     /locus_tag="LSX49_003396"
     CDS             2119..3885
                     /locus_tag="LSX49_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL7169764.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSVQSV
                     ARNLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGK
                     GWIYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQA
                     QSNGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMIFAATVEHAKEIVGLLPA
                     EDAALITGDTPGSERDVLIDDFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVS
                     LYQQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFA
                     NTFWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRC
                     RECDTILVDPDDMLKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSE
                     RFRLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADVLAQQALLRHPDFVVARMKGQY
                     WQVREKVFDYEGRFRRAHELRG"
     gene            4010..4294
                     /gene="rplY"
                     /locus_tag="LSX49_003397"
     CDS             4010..4294
                     /gene="rplY"
                     /locus_tag="LSX49_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HBL7169765.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAVELDH
                     DKVMNMQVKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLLHIDFVRA"
     gene            complement(4433..5440)
                     /gene="yejK"
                     /locus_tag="LSX49_003398"
     CDS             complement(4433..5440)
                     /gene="yejK"
                     /locus_tag="LSX49_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HBL7169766.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            5622..5849
                     /locus_tag="LSX49_003399"
     CDS             5622..5849
                     /locus_tag="LSX49_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HBL7169767.1"
                     /translation="MPQISRYSDEQVEQLLAELLNILEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            5869..7629
                     /gene="pbgA"
                     /locus_tag="LSX49_003400"
     CDS             5869..7629
                     /gene="pbgA"
                     /locus_tag="LSX49_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HBL7169768.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            7704..7780
                     /locus_tag="LSX49_003401"
     tRNA            7704..7780
                     /locus_tag="LSX49_003401"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7738..7740,aa:Pro,seq:ggg)
     gene            complement(7891..8834)
                     /locus_tag="LSX49_003402"
                     /pseudo
     CDS             complement(7891..8834)
                     /locus_tag="LSX49_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247409.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            9154..9801
                     /gene="narP"
                     /locus_tag="LSX49_003403"
     CDS             9154..9801
                     /gene="narP"
                     /locus_tag="LSX49_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HBL7169769.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            complement(9836..10888)
                     /gene="ccmH"
                     /locus_tag="LSX49_003404"
     CDS             complement(9836..10888)
                     /gene="ccmH"
                     /locus_tag="LSX49_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis thiol:disulfide
                     oxidoreductase CcmH"
                     /protein_id="HBL7169770.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVPEGKRAGYVVYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSPQESK"
     gene            complement(10885..11442)
                     /gene="dsbE"
                     /locus_tag="LSX49_003405"
     CDS             complement(10885..11442)
                     /gene="dsbE"
                     /locus_tag="LSX49_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HBL7169771.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
     gene            complement(11439..13382)
                     /gene="ccmF"
                     /locus_tag="LSX49_003406"
     CDS             complement(11439..13382)
                     /gene="ccmF"
                     /locus_tag="LSX49_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis heme lyase CcmF"
                     /protein_id="HBL7169772.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGG
                     LLCLFDPRYRKRVNPQKTAPEAA"
     gene            complement(13379..13858)
                     /gene="ccmE"
                     /locus_tag="LSX49_003407"
     CDS             complement(13379..13858)
                     /gene="ccmE"
                     /locus_tag="LSX49_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HBL7169773.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            complement(13855..14064)
                     /gene="ccmD"
                     /locus_tag="LSX49_003408"
     CDS             complement(13855..14064)
                     /gene="ccmD"
                     /locus_tag="LSX49_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HBL7169774.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            complement(14061..14798)
                     /gene="ccmC"
                     /locus_tag="LSX49_003409"
     CDS             complement(14061..14798)
                     /gene="ccmC"
                     /locus_tag="LSX49_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HBL7169775.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSILGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            complement(14840..15502)
                     /gene="ccmB"
                     /locus_tag="LSX49_003410"
     CDS             complement(14840..15502)
                     /gene="ccmB"
                     /locus_tag="LSX49_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HBL7169776.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            complement(15499..16116)
                     /gene="ccmA"
                     /locus_tag="LSX49_003411"
     CDS             complement(15499..16116)
                     /gene="ccmA"
                     /locus_tag="LSX49_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HBL7169777.1"
                     /translation="MLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLL
                     RLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDG
                     DTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
                     GVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAA"
     gene            complement(16135..16737)
                     /gene="napC"
                     /locus_tag="LSX49_003412"
     CDS             complement(16135..16737)
                     /gene="napC"
                     /locus_tag="LSX49_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HBL7169778.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            complement(16747..17196)
                     /gene="napB"
                     /locus_tag="LSX49_003413"
     CDS             complement(16747..17196)
                     /gene="napB"
                     /locus_tag="LSX49_003413"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HBL7169779.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQDRMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            complement(17193..18056)
                     /gene="napH"
                     /locus_tag="LSX49_003414"
     CDS             complement(17193..18056)
                     /gene="napH"
                     /locus_tag="LSX49_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HBL7169780.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVIILVGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AATDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            complement(18043..18738)
                     /gene="napG"
                     /locus_tag="LSX49_003415"
     CDS             complement(18043..18738)
                     /gene="napG"
                     /locus_tag="LSX49_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HBL7169781.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            complement(18745..21231)
                     /gene="napA"
                     /locus_tag="LSX49_003416"
     CDS             complement(18745..21231)
                     /gene="napA"
                     /locus_tag="LSX49_003416"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic nitrate reductase subunit alpha"
                     /protein_id="HBL7169782.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            complement(21228..21491)
                     /gene="napD"
                     /locus_tag="LSX49_003417"
     CDS             complement(21228..21491)
                     /gene="napD"
                     /locus_tag="LSX49_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HBL7169783.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFTGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            complement(21481..21975)
                     /gene="napF"
                     /locus_tag="LSX49_003418"
     CDS             complement(21481..21975)
                     /gene="napF"
                     /locus_tag="LSX49_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HBL7169784.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGSYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDLQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
BASE COUNT         5418 a         6299 c         5534 g         4893 t
ORIGIN      
        1 gtggttgaca tgcatcaaca aaggaagcct tttagcttcc tcgttgtgca atagatcacc
       61 gttttttcgg ccgactggcg tacagacaga agagaatgga gctggttgca cagaatgcaa
      121 ttgaccaaat catcggccat gcagagttaa aggtcgcaag agaaagtaat gcgccaacaa
      181 ttgcccctat gccgaaacgg aaggttcctg ccagcgaaga tgccgttccc gccatatggg
      241 gaaactcatc aagaatgacc gccatcgcat tggatgacac catcgacacg cagcccacaa
      301 acgccgcaac gccaaccacc agcgaccaga atcccagccc cagcagtgca ctgatgacca
      361 tccacgctgc cataataaac tgtatccaca accccgagcg gaacatattt aacgcgccaa
      421 tacggcggac gaagcggctg ttaaagatgg tcatcacgaa cagaaaaaga atgtttagcg
      481 caaagtaata accaaagttt tccggcgcga cgtggttgat ttcaatgtag acaaacggtc
      541 cggcgcttaa gaatgagaac atcccggcaa agctgaaacc gctggccagc atataactca
      601 ggacacgctt atgacggaac agcgccgcaa agttaccaat agtggtacga atgtgaaaag
      661 gctggcgacg ctccggtggt aaggtttctt tgatcagaaa gaagatcatt gccgaagcca
      721 gaatcgccgc cacggcgagg atccagaaga tgtaatgcca gctcagccac accagcaccc
      781 agccgccaac tatcggtgcc atcagcggtg caatggtcgt caccagcatg acaaacgaca
      841 tcatccgtga gaactcttct ttcgggtaga tatcacgcat caaagcgttg ataaccacgc
      901 tggccgcagc cgcagccagc ccgtggaaga aacgcatcac aatcagctga tcgatggttt
      961 gtgccaacgc acacgccacc gcggcggcgg caaacaccag cgtaccgcca agaaccaccg
     1021 gcttacgccc gaagctgtct gccatcggcc cgtagattaa ctgccccaac gcaaagccca
     1081 gaatataagt actgagggtc atctgcgtac tgcccgccgg tacaccaaac tgcgctgaaa
     1141 ttaccggtag cgcaggcaga tacatatcaa tcgacagcgg catcaacatg gccagcaggc
     1201 caaggataaa aacaatagca aacgacgaat gctgtcgggt ggtcacaacg ggctcctgaa
     1261 agtcattgaa aagttagacg acgctggcaa tttcttcttc agttaacgga cgatattcac
     1321 cgggggctaa atcagcatcc agcgtaatac cgccaatacg ttcacgatgc agctcaacca
     1381 catggttacc cacggcggcg aacatacgtt tcacctgatg ataacgccct tcgctgatgg
     1441 tcaaacgaac ctgcgttggg gtaatcactt ccagcaccgc cggcttagtg agatcttttt
     1501 cgttatgcag ctgcacgcct ttagcaaatt gctctgccgt atcgtcagct acgggtgatt
     1561 ccagcgtcac cagataggtc ttctcgcaat gatggcgcgg ggaagtaatg cggtgcgacc
     1621 actgaccatc atctgtcatt agtaccagac cggtggtatc gatatccaga cgccctgcag
     1681 cgtgcagttt ccacgctacc ggttcatcaa gaaaatagag caccgttggg tgatccgggt
     1741 cgtccgtgga gcaaacatag ccctgaggct tattgagcat gaagtaacgt ggaccgtgtt
     1801 gctgcgccag cgggttgcca tcgtaagcga catcatgttc agggagcagt ttgaacgctg
     1861 cattacggac gatttcgcca tcgacggtga cacgattgcc gcggatttca cgcccggcaa
     1921 tagcacggct aacgccgagt tgctgtgcga taaatttatc aagtcgcatg tgtgtgattt
     1981 tgcctgtaaa aaacggaggt cgggtaatga cccgaaaatc tgaactgttg tctgcccagt
     2041 atagcggtct aataacttcc ctcaagggaa aaagatccgt ggcatactat tagcagaata
     2101 atctacctac gcgagaccat gatttttaca ctccgcccat atcagcaaga agccgtggat
     2161 gccacgctca accattttcg tcgtcataaa acccctgccg taatcgtgct gcccaccggt
     2221 gcaggtaaaa gcctggtgat agcggaactg gcgcggctgg cgcgtggtcg cgtgctggtg
     2281 ctggtgctgg cacacgttaa agaactggtg gcacaaaacc atgcaaaata tcaggcgctg
     2341 gggctggaag ccgatatttt tgccgccggg ctaaagcgca aagagagcca cggtaaagtg
     2401 gtatttggca gcgtgcagtc ggtcgcccgt aatcttgatg cctttcaggg tgaattttcg
     2461 ctgttgattg tcgatgaatg ccaccgtatt ggtgacgatg aagagagcca atatcagcaa
     2521 atcctcactc acctgaccaa agtgaatccc cacttacgcc tgctggggct gactgccacg
     2581 ccttttcgac tgggcaaagg ctggatctac cagttccatt atcacggcat ggtacgcggc
     2641 gatgagaaag cccttttccg tgactgcatt tatgagctgc cgctgcgtta tatgattaaa
     2701 cacggctatc tgacgccgcc agaacggctg gatatgccag tagtgcaata cgatttcagc
     2761 cgcttgcagg cacagagtaa cggactgttc agcgaagccg atctcaaccg cgagctgaaa
     2821 aaacagcaac gcattacgcc acacatcatc agccaaatca tggagtttgc tgcaacgcgc
     2881 aaaggggtga tgattttcgc cgcgacggtc gaacacgcaa aagagatagt gggattactg
     2941 cctgccgaag atgcagcact gattactggc gacacacccg gctctgagcg cgatgtgtta
     3001 attgatgatt ttaaagccca gcgttttcgc tatctggtca acgtcgcggt actgaccacc
     3061 ggatttgacg ccccgcacgt cgatcttatc gccattctgc gccctaccga atcggtgagt
     3121 ctttaccaac aaattgtcgg gcgcggtctg cgcctggccc ccggcaagac tgattgctta
     3181 attcttgatt atgcgggtaa ccctcacgat ctctacgcgc cggaagttgg tacaccgaaa
     3241 ggcaaaagtg acaacgttcc ggtacaggtt ttctgccctg cctgcggttt tgccaacacc
     3301 ttttggggga aaacgaccgc cgacgggaca ttgattgaac actttggtcg tcgctgtcag
     3361 ggatggtttg aagatgacga cggacatcgc gaacagtgtg acttccgttt ccgttttaaa
     3421 aattgcccgc aatgtaacgc tgaaaatgat attgccgccc gccgttgccg cgagtgtgac
     3481 accattctgg ttgacccgga tgatatgtta aaagcggcgc tacgactgaa agacgcgctg
     3541 gtattacgct gtagcggcat gtctttgcag catgggcacg acgaaaaagg cgaatggttg
     3601 aaaatcacct attacgatga agacggcgcg gatgtgagtg agcgtttccg tctgcaaacg
     3661 cccgcccagc gaactgcctt cgagcagctt tttatccgcc cgcatacgcg cacaccgggc
     3721 atcccgctgc gctggatcac cgccgccgat gtcctcgccc agcaagcctt attgcgacac
     3781 ccggattttg tcgtcgcccg catgaaaggc cagtactggc aagtgcgtga aaaagtgttc
     3841 gattacgaag gtcgttttcg tcgggcgcac gaattacgcg gttaatggta gttttgattg
     3901 atgtataagg cgattgagta tagaatctcg cccgcttttg catacgcaaa gcagatcact
     3961 tacctgttgc tgggtcgcct gtagcaggat taatttaaga gagaaagaaa tgtttactat
     4021 caacgcagaa gtacgtaaag agcagggtaa gggtgcgagc cgccgcctgc gtgccgctaa
     4081 caagttcccg gcaatcatct acggtggcaa agaagcgccg ctggctgtcg aactggatca
     4141 cgacaaagtc atgaacatgc aagttaaagc tgaattctac agcgaagttc tgaccatcgt
     4201 tgttgacggt aaagaaatca aagttaaagc tcaggacgta cagcgtcacc cgtacaaacc
     4261 gaagctgctg cacatcgact tcgttcgcgc ttaattgctg aataagttgt aaaaaacccc
     4321 gctccggcgg ggttttttgt ctctgcaaat tatgcctgat tacggtattg ctattttttg
     4381 caggccagat aaggcgttca cgccgcatct ggcattcaga acacaaaacc gattaattgc
     4441 cgccagacgt ccggcgctgc aattgatcgc gcaagttcgg cggcgtgcct ttaatggtca
     4501 gggtatcggt tgctggatcc cagaagatgc gttcacctaa cagcatcgca tcaaagttaa
     4561 tagtcaagcc accgccgcta ccggcaaact tcgtcaactg acgcagtgtg ctacggtctg
     4621 ccgggaagct ctcttccagt tcgtagcctt tttcagccgc aaactccgtg aagctcactt
     4681 cgctgacgcc tgccagctct ttcgacagcg attccagttc aatctcttca cctgcctgta
     4741 gctgctcatt acagtagcta taaacctgct ggcgcacgtt ctgtcgctct gctttatcca
     4801 gttgtgcttc ggcagtgaaa tcatcgaccg cttgcaacag cccacggttt tgcgctttcg
     4861 cgtttaaccc ttcgctggca ccgaggaaat ccataaagaa atccgccact ttgcgcccta
     4921 ctcgcccttt caggaaagtg agatagcggg tcgactctgg attggtttcc cactcggtta
     4981 aatcgatacg cgcaacaata tccgcatgat tgatatcaag ataatgggtt gggttgatgt
     5041 cgagattttc gttaacacgc atactgctca ggttgctcag aactgccacc agcagatact
     5101 ccaccgccag atagcgatag tggcaaaaca gcacgaatcc accgtcagca aaaggatatt
     5161 tcgctaattc gtcacgcagg cgaccggttg ccgcgcggct aaatgccaga aagtcctctt
     5221 cgccctgacg ctgtaagcgc agcgtctgcg ccagttcact ctcttcgcta aacaagccgt
     5281 aagctttatt tttggcgcta tagacccgat gcagttctgc caccatctca acgacggttt
     5341 ccgtcggttc cagcaatgaa tcgcgcaaca ccagctcaag gttctgctca tcacgcttga
     5401 taagctggtg cagagcaatc tggttgatat ccagactcat gataaactct cctttaagac
     5461 cgggcggtat tcaaccaccg ccggttaagc gacgcaataa aagatggcgg tcattttaca
     5521 gaaggcggcg taacgagaat gatttaacgc ataaaaaagc agaaaaaaaa ccgttgctac
     5581 ggtaatatgt tgccctttca tcaactaact gatttcgatt tatgccacaa atttcccgct
     5641 acagtgatga acaggttgaa caattgctcg cagagctgct caacatactg gaaaaacata
     5701 aggctccgac cgacctttcc ctgatggtgt taggcaacat ggtcactaac cttatcaaca
     5761 ccagcattgc cccggcccaa cgccaggcaa ttgccaactc ttttgcccgc gccttacagt
     5821 cctctatcaa cgaagacaaa gcgcactaag ggaaacagat aacaggttat ggtaactcat
     5881 cgtcagcgct accgtgaaaa agtctcccag atggtcagtt gggggcactg gtttgcactg
     5941 ttcaatattc tgctttcgct cgtcattggc agccgttacc tgtttatcgc cgactggccg
     6001 acaacgcttg ctggtcgcat ttattcctac gtaagcatta tcggtcattt cagcttcctg
     6061 gtgttcgcca cctacttgct gatcctcttc ccgctaacct ttatcgtcgg ctcccagagg
     6121 ctgatgaggt ttttgtccgt cattctggca acggcgggaa tgacgctatt actgatcgac
     6181 agcgaagtct ttactcgttt ccatctccat cttaatccca tcgtctggca gctggttatc
     6241 aacccagacg aaaatgagat ggcgcgcgac tggcagctga tgttcatcag cgtgccggtt
     6301 attttattgc ttgaactggt gtttgcgacg tggagctggc aaaagctgcg cagcctgacg
     6361 cgtcgtcggc gcttcgcgcg cccgctggcc gcattcttat ttatcgcctt tatcgcctcg
     6421 catgtggttt atatctgggc cgatgccaac ttctatcgcc cgatcaccat gcagcgcgct
     6481 aacctgccgc tttcgtaccc gatgacggca cgacgttttc ttgagaagca tggcctgctt
     6541 gatgcgcaag agtatcaacg ccgtcttatt gagcaaggca atccagacgc cgtttccgtt
     6601 cagtatccgt taagcgaact gcgctatcgc gatatgggca ccgggcagaa tgtgctgttg
     6661 attactgtcg atggcctgaa ctactcacgc ttcgagaagc agatgcctgc gctggcaggt
     6721 tttgctgagc aaaatatttc gttcacgcgt catatgagct ccggcaacac tacagacaac
     6781 ggcatctttg gcctgtttta tggcatctcg ccaagctata tggacggcat tttgtcgacc
     6841 cgtacgcctg cggcgttaat tactgcgctt aatcagcaag gctatcagct ggggttattc
     6901 tcgtcagatg gctttaccag cccgctgtat cgccaggcat tgttgtcaga tttctcgatg
     6961 ccgagtgtac gcacccaatc cgacgaacag accgccacgc agtggattaa ctggctgggc
     7021 cgctacgcac aagaagataa ccgctggttc tcgtgggtct ctttcaatgg cacaaacatt
     7081 gacgacagca atcagcaggc atttgcacgg aaatatagcc gggcagcagg caatgtcgat
     7141 gaccagatca accgcgtgct caatgcactg cgtgattctg gcaaactgga caatacggtg
     7201 gtgattatca ctgccgggcg gggtattccg ctgagcgaag aggaagaaac ctttgactgg
     7261 tcccacggtc atctgcaggt gccattagtg attcactggc caggcacgcc ggcgcagcgt
     7321 attaatgcgc tgactgatca taccgatctg atgacgacgc tgatgcaacg cctgctacat
     7381 gtcagcacac ctgccagcga atattcgcaa ggtcaggatt tgttcaaccc tcaacgccgc
     7441 cattactggg ttaccgccgc ggataacgat acgctggcaa ttaccacccc gaaaaagacg
     7501 ctggtgctga acaataacgg taaataccgc acttacaact tacgtggtga aagagtgaaa
     7561 gatgaaaaac cacagttaag tttgttattg caagtactga cagacgagaa gcgttttatc
     7621 gctaactgat taattataaa tcagttagca aaatatctta cttgcaatcg gtgtggaaaa
     7681 cggtagtatt agcagccacg agtcggcacg tagcgcagcc tggtagcgca ccgtcatggg
     7741 gtgtcggggg tcggaggttc aaatcctctc gtgccgacca aaaatcccaa gaaaaccaac
     7801 ctattgcggt tggttttttt atatctgcat ttaattcgat aaacagaccg cgacacatca
     7861 cggcctgttt attttctgtt atcagaacgt ccagaccaca cccgcctgag ttgtgctgct
     7921 ttcttcacgg gagaaacggc tgtcgatacc aagcgttagc cccgtcaatg tttgctcaaa
     7981 gccagcgcct gcatcagtgg tcacgttgtt gcggctgtta attgccgaac tccacatcgc
     8041 cgtatcgtaa ttaacgcctt ttacgctacc aagacgccca cgcacggtgt ccagttctgc
     8101 atcaaatacc agcggttgtg ctgccgccat attcagcaca tccgtggttg aagggggcat
     8161 ttgtgcgcga ttctctgcga gactccagct atggttgcca ttatccagca aggtatattc
     8221 atacgtactg atatcaacaa cgcctccggc attgcccaac gtaaatgccg catcaccgcg
     8281 cccgttgtta ccagtgtaag gttatctcct gctgccgggc tggcaccggt gtccgtcacg
     8341 aatattttga aatcacctgt tgctttaacc tccagtagcc ctcccttttc tataacggca
     8401 aagacggcaa tcccatcttt ttcaacaatt aagcgccctc ctttaatcgt gggatcagtc
     8461 gccgcgccat aaacctgtag cactccatta ttgatcgtag tctggtttac cgcgccaccc
     8521 atttgaacaa tttgataacc atcatttaat actgagtatt ctgcggtgcc atttatttca
     8581 atgtactgat atcccccgtt aatttcagta ttactactta caccaaattc ttatatatgc
     8641 tgttctccgc caggattgat tttcgtatta taggcggccc tacaaaccag ctggatatct
     8701 ttttccagga caacaccatc aactgtctca ccatactcaa cagttgatgc caatgctatg
     8761 ggcgaatata acgctgtagc caccagaaca gatattgcgg aacgacaaag agaaacagaa
     8821 ccagattggt gcattaagct ttcatcctat gaaattaatt gctgttaaaa gcattgggga
     8881 cagaaaatac ccatagctcc atacccggag tcagttttta aaaactgttt aaagaaatgc
     8941 acaagtattg tgattgattt tttagttgtt tttcctgatg agaagctgat gcaaaattcc
     9001 gtctttataa taaagatgat gccaaagcga acgacaaagt tgtagttttc actacatgtc
     9061 catacataaa atggggtaac attcacgcgc ctggtagcgt taccaacgct acgctcaaac
     9121 ataatgattc taataaaacc tcaggagact actatgcctg aagcaacgcc ttttcaggtg
     9181 atgattgtgg atgatcatcc acttatgcga cgcggtgttc gtcagttact ggagcttgat
     9241 tctggctttg aagtggtcgc cgaagcgggc gacggcgcaa gcgcgatcga tctggcgaat
     9301 agactggata tcgacgtgat cttgctggat ctcaatatga aaggcatgag tggcctggat
     9361 accctcaatg ccttgcgcag ggatggcgtt accgcgcaaa ttattatcct gaccgtatca
     9421 gatgcctcca gcgatgtctt tgcactgata gacgcaggcg cagacggtta tctgttgaaa
     9481 gacagcgacc cggaagtgtt actggaagcg attcgtgccg gagcgaaagg cagcaaagtc
     9541 tttagcgaac gcgtcaatca gtacttacgt gaacgtgaaa tgtttggcgc ggaagaagac
     9601 cccttcagcg tgctgacaga acgcgagctg gatgttctgc acgagctggc acaggggctg
     9661 tcaaataaac agattgcctc ggtgttgaat atttccgagc agacagtaaa agtccatatt
     9721 cgcaatctgc tgcgtaaact caacgtccgc tcacgcgtgg cggccaccat tctgttcctg
     9781 caacaacgcg gggcacaata aaaatagccc gatggcatca ccatcgggcc actttttatt
     9841 tactctcctg cggcgacaaa tgttgcatcg cctgcgcgat actacgttcg atcaccgcac
     9901 ggcgagtatc gttggcaggt aagagtttca acatcatttc ccacgcggca acggcttcgc
     9961 caaatcgttg ctgctcaaag gcattaaatg catacatgct taacacacgg atattgctat
    10021 ggtccgttct caccaactgg cgcagcagtt cgccgccgag gcggttgtcg ttgggatcag
    10081 atgaacgtgt caacgcttca gcgtatccca gtgcagcatc gctgtttttc ggatcgaggc
    10141 gatacgcagt ggcgtatgca tcggtggcga tactggcgtt acccagcgcc atgccaacgc
    10201 ggcccaacat aatccagcct tctatatctc ccggattttt ttgcagttga gtacgcatcc
    10261 ccagcgcaag gcgcgacatc tcttcttcgt tgagcggatc ggctttcgga tccagcgccc
    10321 tgtccagtaa cgccggagcc tgtgccgtgg cctgctgcca gattttcacc tgctgataat
    10381 tgccagtctg gtagtagctg acgccagcca caattaacgc caccacaata cccggcagat
    10441 aaacaacata tccggcacgc ttaccttccg gcacgctttg ttctggaaac gcttccggca
    10501 ccacgcgtac ccgacgccgc gaacgggcgt atatgaccca accgccaatg ccaatagcca
    10561 ctactggcag cacccacagc agcacggtca gcggcgttaa cggcggatcg taagtgacga
    10621 agttgccgta acgcgccacc atataatcga caatctcttt cttacttttg ccttcctgca
    10681 tcagttcata cactttctgg cgcaggtcgg tggcaatcat cgagttggaa tcggcaatgc
    10741 tgttgttctg gcatttcggg cagcgcagtt cttcagtgag ctgacggaac tgttgttcct
    10801 gtgcttcatc tttaaactgc aacacgtcga tggtcgccag cgctgagccg gagatcatca
    10861 gcatcagcac gcccaataaa aacctcattg tgcggcctcc ttactgtatt tctcccacag
    10921 tggcttgatc tcttcttccc agacgcgagg attgagatcg cccgcatggc gatagcgaat
    10981 gatgccgttg ccgtcaataa ggaacgtttc tggcgcgcca tagacaccga gatccagccc
    11041 taacatgccg tcgccatcaa acaggcttag cgcgtaagga ttgcccagct ctttcagcca
    11101 gctgattgcc ttctggcgat cgtctttata gttcatgccg accacgcgga tgccctgcgc
    11161 agaaagctga ttcagatatt gatgttccgc acggcaggtc ggacaccagg tcgcccagac
    11221 gttaagcagc actggtttgc cctgagtcag cacatccgcc tgataaaact gccccggatt
    11281 gtccagtgat tcgaggcgaa acttcggcac tggcttgcca atgagcgccg attccagatt
    11341 ggtcggatca tccccttcgg cattacgcgc cagctgccac agcagcgccg cggcaatcgc
    11401 caggaagata atcaacggaa ttaacaatac cttgcgcttc atgcagcctc cggcgcagtt
    11461 ttctgcgggt tcacgcgctt acgatagcga ggatcaaaca gacacagcag tccgcccaac
    11521 gccatcatca gcccgcccgc ccaaatccag cgaacaaatg gtttgtagta aagacgcacg
    11581 gcccacgcgc cgttttccag ctcttcaccg agcgccgcgt acaggtcacg cgtgatgcca
    11641 ccgtcaatcg ccgcttcggt catcatcgac ccggcagtgt tgtaataacg tttttctgca
    11701 tacagcactg tttccggctt gccatctcgc gttacgccga tagtcgccac accgccacgc
    11761 cagtttggac cagtcacttc tttgacatca cggaaggtga agcgatattc atgaatatcg
    11821 acgctatcgc cggacttcat gcgcacatca cgctcaacgc tatagttctg actaaaagca
    11881 atgccaacaa ttgtcactgc cagccccagg tgagctgcca ccatccccca ataactgaag
    11941 gtggttttcg tgccgcgtga aatacgcagc gcagcttccg caattgccag caccgcaatc
    12001 cagcaggcca ttgccaggcc gagcaccgtc atcgccacaa ctttgctttc gaacagccac
    12061 ggcaacagca gcgacagcac cagcgtagag atgaaggcga taatcaacaa attgcggatt
    12121 ttacgtgggc gatcgcgtcc ccagcgcacc agagggccga caccaagcag tagcgcaaac
    12181 ggcaccatca gccaggtaaa catggtgttg aagaacggtt cgccaatcga aatactgccc
    12241 agtcccagtt gcttgtgcac cagcggcagc aacgtcccca gcaacaccac cagcatcgcg
    12301 gctaccagca aaacgttgtt cgctaacagc aaagattccc gcgaccacag cgcattgttt
    12361 acgcgtgagc gaactttgtg tccacgcgcg gcaaacagca gcagcgaacc gccaatcacc
    12421 agcaccataa aggcgaggat aaacataccg cgcgccggat cagacgcaaa cgcgtgtacc
    12481 gataccagca cgccggaacg cacgaggaaa gtccccagca gacacaacga gaaggcactg
    12541 attgccagca gtaatgtcca cgctttgaag ctggcgcgtt gttcagtgac cgccagtgag
    12601 tgcatcagcg cagtccccac cagccacggc ataaacgagg cgttttctac cggatcccag
    12661 aaccaccagc cgccccagcc gagttcgtaa taggcccatg cggaaccgag cacaatgccg
    12721 agcgtcagga agatccacgc agccagcgtc cacggacgag taaaacgcgc ataagtgctg
    12781 tccagacgcc cactcaacaa agatgcaatg gcaaaagcaa acgccaccga gaaaccgacg
    12841 taccccatat agagcagagg cgggtggaaa atcagccccg gatcctgcaa caacgggtta
    12901 agatcgcgcc cttcaatcgg gaaattcggc agcgtgcgtg agaacgggtt agaggtaaag
    12961 agaatgaaca gcaaaaagcc gacactgacc atccccatta tcgccagtac gcgggcaaca
    13021 atatccagcg gaatacgctg actaaaaatc gctaccgcaa aggtccagcc gctcatcagt
    13081 agcacccaca gcaggagcga gccttcatgc gcgccccagg tagccgccac gcgataccac
    13141 accggaagct gggtattgga gttgctggca acataggtga cggtaaagtc gttgaccacg
    13201 aaagcattga ccagcaccag aaatgcgcca gccacagaca taaacagcag ccaggcaaac
    13261 aagcgggaag acgccatcat gcgcgcgtcc ccgcgcgcca cgccccatag cggatacaca
    13321 gacagcagca gcgcaattcc tagcgccaga cacagcagcc cgttaccaat ttctggcatc
    13381 atgatgctgg gtccttataa acactcgccg ggcgacggtg gttagcttcc atcgctttct
    13441 caacttctgg cggcgtgtag ttttcatcgt gtttcgccag cacttctttc gcgaggatat
    13501 gattgccttt ttccagttcg ccctgcacca caacgccctg cccttcacgg aacagatccg
    13561 gcaaaatgcc ttcgtaagag acatctactg aaccttcagc gtcgtaaatg gtgaaagtta
    13621 cttttagcga attgggatcg cgctgcacac tccccggcat caccatcccg ccaacgcgca
    13681 gacgctgacc gacttccggc atctgctgag tttcacgctt gccgtagaga atctcccccg
    13741 gcgtataaaa gagatcgata ttcgagcgca gcgcatatag caccagaccg atagtcagcg
    13801 ccagccccgc cagcacggca caggcaatcc acaagcggtt tttacggcga atattcatgc
    13861 agcctcctgc tgttgcgcag cacgtaaacg cgcctcacgc gcccgctgtt gcgccacgcc
    13921 acgcagaatt gcgcgatgtt gcatcaccga gtgcacgact aaaaccacca gcggaataac
    13981 ggtcatcacc accgccagcc agacaaaaaa ggcgtaaccg cccattgcga aaaattcatt
    14041 ccaggaagca aatgcagggg tcatttacgg cctcttttca gtatcagttc actcacccac
    14101 ggacggcgtt tttccatcag caaaatcaaa ttacgcatcc gcatcagcgt cagcgtggca
    14161 gacaggagca ggaagcccaa aatcgaccag cgcagcggcg aacgcatcgc cggatcgata
    14221 ctttgctgca ttcgcgttga tccctgatgc agggtgttcc accactctac ggagtaatga
    14281 ataatcggca gattcaccac gccaatcagc accaggatac ctgccgcacg cccagccaga
    14341 cgacggtcgt cgaaggcgtg ccacagggca atgacaccaa catacagaaa cagcagcacc
    14401 agttcagaag tcagacgtgc atcccatacc caccaggtgc cccacatcgg ttttccccat
    14461 gcagagccgg taaccagggc aataaaggta aacacggcac caatgggggc catcgccgcc
    14521 accgccaggt tggccatttt catctgccag acaaggccaa taaacgccgc caccgccatt
    14581 gatgcataaa tgcccatcga ccagatcgcc gcaggcacat gcaggtagat aatgcggtag
    14641 ctatttccct gctgataatc agccggagca aagccgaacc cccagatcca gccgacggta
    14701 agcacgacca cactggcaat tgccagccac ggtataaacc agccacagat ttgatacagc
    14761 cgtggtggga tcgccagttg atgcagtgtt ttccacatag tttcgatacc agactcgaac
    14821 aaaaatcagt aatccagcgt tattgaatgc tgattcgtaa cgctgccgcc gtcgcaaaag
    14881 gacttaatgt cgcggtgcct gccagcaacg cgcctaaaat tgccagatac ccatcaacgg
    14941 gcaaatgcat agaagccgcg tccatcgcgg cggtggcaaa gatgagtaat gggatagtca
    15001 gcggtaacac cagtatgctg agcagcacac caccgcgctt aagtcccact gtcagcgcca
    15061 cgcccggcgc accaagaaag ccaagcgtag gggttcccag cagtagcgtt aacgccatca
    15121 cttgccagcc ataaacatcc attcccagta gcattgctac caggggcgaa aggatgagta
    15181 acggcagacc ggttaccatc cagtgcgcca tcaccttcgc cagcacaacg gcgggcaagg
    15241 gtaacggcaa caacatcaat tgttcaagac tgccgtcctg caaatcgtca cggaacagtc
    15301 gctcgagtgc cagcaaggat gaaagcagcg cggcaaccca gataataccc ggcgcaatac
    15361 gcgccagcag ttgcggctcc ggaccgatac tgagcggaaa aagggtaatg acaatcagga
    15421 agaaccacag cgggttggcg atttcggcgc tgtggcgaaa cgctacgcgc agctcaagac
    15481 ggaaaatgcg ccagaacatc atgcggccct cgtttgcgtc agtgaaatgc ggcgaatttt
    15541 actttcagca acgttgagcg gctggtgggt agtcagaatc acaatccccc cctgctccgt
    15601 atgctgcgcc atacgctggg tcagacgatc gacgccatta acgtcaatcg cggtaaaagg
    15661 ctcgtcgagg atccataacg tggcacgggt cagccacaga cgcgctaaag cgacgcggcg
    15721 ttgttgcccg gcagaaagtt gatttaccgg aatatcttcg aatccggcaa gcccggcctg
    15781 cgccagggct tccagacatt gtgcggtatc gccatcgcga tgataaaagt gcagattttc
    15841 taacgccgtc agccgggttt tgatccccgg ctgatggcct atccataaca ggttttgatg
    15901 gtagctgtcg cgtacctgat gcaagggctg cccttgccag agaacctcgc ctgcatcagg
    15961 gcgagacaac cccgtcagca aacggagaag cgttgtcttc cccgcgccgt tgctaccggt
    16021 gatttgtacc cactctcctg cgttcagcgt aaatgataaa ccactaaata aggttcgttc
    16081 atcccgctcg caaagtaact ctctggcttc aagcatactc acgcaataac cctgttaaaa
    16141 acctggctcg acttcacgca tgtcgggcag cttgtgcgct atccctttat ggcaatcaat
    16201 acaggtttgc ccatctttca ccgcctggtc atgcatcttc gcggcaaccg atttctgggc
    16261 ggttgtatcc atatactcga agttgtgaca gttacggcac tcctgcgagt tgttgtcctt
    16321 catgcgccgc cactcattct gtgccatcgt caggcgatga gcttcaaatt tctgcggcgt
    16381 gtcaataacg ccaaaaattt taccatacag ctctttactt gctttgagct tgcgtatcat
    16441 ctttggcaca aactcgtgcg gaacgtgaca atccggacag gtcgcacgga cgccgctacg
    16501 gttgttgtag tgcacggaat ccatgtattc ctgatacacc gtgttacgca tttcgtggca
    16561 gctaatgcag aactcttcgg tattggcttt ttccatcccg gtgttaaagc cgccccagaa
    16621 gacgatgcca ccgacaaaac cgatcaacag cagcgtcccc agcgccagac ggctgggggt
    16681 acgccaccat ttccacaggc gcttaatcag accaggctta cggtcagaat ttcccataat
    16741 aacctcttat ttcccgtaac cttttgacgg ggtaaaggta ttccccacga ttggcgcggt
    16801 atcggcctgc ggtacgtgac attgcagaca gaaataacga cgcggagcca cttccgcgcc
    16861 cactttgccg tcgctgtcca taaagtgagt aggactaatg cgcggcgcgc cagtggtgcg
    16921 ataactttcg acaccgtggc actgcaagca gcggttggta ttggtcgtta cctgataacc
    16981 ttcaacgcta tgcgggatca ttggcggctg attcacatag ttcagcggca tccgatcctg
    17041 ctcttttggc atccgaatgg ccccttcctg cgtcccggat acttccggcg actggctaaa
    17101 atcgacgcca ttagccgccc aaaccgcgcc gcttaccacc agggccagca tcgccgtcca
    17161 ttgacacagc gctttcttca ggtcatggct tttcatgatt tcgctcccga actccatcgt
    17221 gtagttattg taaatacatc ctcagaacag acatccacgc agcgaccgca cgtcatgcaa
    17281 tcgcggctgg tgacctgcac cgggctttgt tcatccagca ccggggcacg tagcacatgc
    17341 ggttccgggc aaacatgaaa acaatccata cagcggttac atttctgccg atcggtggcc
    17401 gcaacggtaa tcacaccttt gctacccagc acgccataca gtgcaccaac cggacaaatg
    17461 tgcccgcacc agccgtgttc aacgaccagt agatcaaata aaaacagcgc gagaataagc
    17521 agcgcgccgc tgccgaagcc cattaccagg ctacgcccca tcagggaaac ggggttgatc
    17581 cattcccaga tgagcgtgcc agttaaggcc gatcccacca gaatgatcac caacagcacg
    17641 tagcgaatgt ggcgagggat cgtcgcagac tgattgaggt caaatcgtct gcgtaaccaa
    17701 tttgctaagt cggtaatcgg gttcagcggg cagacccagc tgcaaaataa tcgctttcct
    17761 gccagggcgt agagcacggt gataatcacc gcaccagtca gcgctaccgt ggcaggcaga
    17821 tgaccgctgg caagactttg cagtgtcatc agcggatcgg tcagtggaac ggtgtcgaat
    17881 aacaggctac tgctgtagtt gccgtgcaag atccacacac caaaccacgg accgctcaaa
    17941 aacatcccca gcacgaagaa ctgacaaagg cgacgtaaca ctaaccaacg gtgactgcgc
    18001 caccagcctt ttttctccag cgcctcgcgc ccggcgtcac gtttacgatt tgccattgtt
    18061 cccctccagc cagccgaagc ggtaatggtg acctaactcc cctttcgcca gtgacagcgg
    18121 taacaccttg attgccggtt gttccagcac gcacactttt tcgcacttac cgcagccggt
    18181 acaggcgtcg ctgtgaaccg tcggcagaaa gcgggcgtgc ttaccggttc gcgtgttgcg
    18241 ctccagctcc agggtgatgg cctcatcaat tttcgggcat tcgcgataac aaacatcgca
    18301 gcgcagcccc tgaaagttga gacagttttc ctggtccacc agtaccgcca gccccatccg
    18361 cgcgtcgtcg atcgattcga tctcacgatc cagcgcaccg ctcgggcaca ctttggcgca
    18421 cggaatgtcc tcacacattt cgcaaggaat atcccgtgcg acaaaatatg gcgtgcccgc
    18481 cgacagacca gaggccagcg tcgccagttt taaggtgtcg taagggcaag cctgaacaca
    18541 ctgaccgcaa cgcacacagg cactggcaaa ggcgttctcg tttatggctc cgggcgggcg
    18601 caaccgcaca ccagatgcgc gtgcggtttg ctgttgtaac cccagcgcca cacccacggc
    18661 agccagcccg cctgctgtgc gaacgacatc gcgcagaaag cggcggcgac cattttgagg
    18721 tttcgctgac cgggacataa tggcttacac cttctccagt ttgaccgcgc acttcttgaa
    18781 gtccgtctct ttcgagagcg gatcggtcgc atccagcgtc agtttgttaa ccagctgtgc
    18841 ggcgtcgaag aacggcatgt acaccaggcc ctgcggcgga cggttacgac cgcgcgtttc
    18901 gacaatcgag atcacttcgc cacggcgaga aaccactttc actttgtcgc cacggcgcag
    18961 atcgcgcgct ttcgcatcca gcgggtgaat aaacagaacc gcttccggga aggcgcggtg
    19021 cagttccggt acacggcgag tcatactgcc ggtatgccag tgctccagga cgcgtccggt
    19081 agagagccac aggtcgtact cttcatccgg cgcttccgcc gcaggttcga acggcagcgc
    19141 gaagatcacc gctttgccat ccggtttacc gtagaacttg tagccttcgc ccgctttcac
    19201 gtacgggtcg ttaccttcgc tgtaacgcca ctgcgtttct ttaccgttca ccaccggcca
    19261 gcgcagaccg cgtgctttgt ggtaatcatc gaacggcgcg agatcgtgac cgtgaccgcg
    19321 accaaaccat gcgtactctt cgaacaaccc tttttgcaga tagaagccca gctcgcgaga
    19381 ttcgtcgttc agctgatctt ccgccagttc ggataccggg aatttgctca cttccggagt
    19441 ggcatacaga acctcataca gcgttttgcc acgcagttcc ggtttcttag ccagcagctc
    19501 ttccggccac acttcttcag ttttgaagcg acgggagaac tgaactaact gccagagatc
    19561 cgattttgct tcacccggtg cctgtacctg ctgacgccag aactgagtac ggcgttcggc
    19621 attaccgtaa gccccctctt tctctaccca cattgcggtc ggcaggatca agtccgctgc
    19681 cagcgcactg accgtcggat atggatcgga aacgatgata aagttgcgcg gatcgcgcca
    19741 gcccggcata cgctcttcat taatgttcgg tccggcctgc atgttattgg tacacatggt
    19801 ccagtaaaca ttcagtttgc cgtctttcag cgcacggtct tgtgccaccg cgtgcagacc
    19861 gattttcgcc ggaatggtgc cactcgggat attccacttc ttctcgcaaa tatcacgatg
    19921 tttctcgtta gtcaccacca tgtccgcagg cagacggtga gcaaaggtgc ccacttcacg
    19981 cgcagtacca cacgcggaag gctgcccggt cagggagaac ggaccgcaac ccggctggga
    20041 aattttgccg gtcagcaggt gcaggttgta gaccaggttg ttggcccaca caccacgggt
    20101 atgctggttg aagcccatcg tccagtagga gatgactttc ttgttcggat cggcatacag
    20161 ctgcgccagt tgttctaact ggtctttcgg cacgccggtc atttcggcgg ttttttccag
    20221 cgtatattca gcaacgaagg ctttgtaatc ttcaaagctc atcggttcgg aggcgtcaga
    20281 acccggattc ttcgctgctt tttccagcgg atgggtcgga cgtaaaccgt agccgatgtc
    20341 cgtcgcccct ttgcgcaggt taacgtgttt gctgaagaag tcctgattta tcgcattgtt
    20401 ttgaatgata tagttggcga tatagttcag gatcaccagg tcagattgcg gcgtaaagat
    20461 gatgccgtta tccgccagct cgaagctacg atgctggtag gtagaaagca ccgccacggt
    20521 aacgttctgg ttagagagac gacggttagt gatgcgcgac cagaggatcg ggtgcatctc
    20581 cgccatgttt gcgccccaca gcacaaacgc gtcagcctgc tcgatgtcgt catagcagcc
    20641 catcggctca tccataccaa aggtacgcat aaagccaact actgccgacg ccatacagtg
    20701 acgcgcgttc gggtcgatgt tgttcgaacg gaagcccgct ttaaacagct tggacgcggc
    20761 ataaccttcc cagatagtcc actgaccaga accgaacata ccgatcgatt ccggcccttt
    20821 ttctttcagg gcggttttga atttctcttc catcacatcg aaggcctgat cccaggtgat
    20881 tggggtaaat tcgccttctt tatcatattt accgtttttc atacgcagca gcggctgcgt
    20941 caaacggtct ttaccgtaca tgattttggg caggaaatag cccttaatgc agttcaggcc
    21001 acggttaacc ggtgcgtccg ggtcgccctg acaagccacc acacgcccct gctgcgttcc
    21061 gaccagaacg ccgcaacccg taccgcagaa acggcacggc gctttatccc atttaatggc
    21121 ttcctgctga ccaacaacgg cgcgggcaac gcccggcacg ctgagaccgg cagccgccgc
    21181 agcggccgca acggcgttag ctttcataaa gctacgacga ctgagtttca tggtgtttcc
    21241 tcaccttgct cttcctgctg gtgataaacc agcgacaccg ccagcacgcc ctctacgttg
    21301 cgtactgact caatggtttg gatcagcgtt tcgctgtctt ctgcttccac caccacaatc
    21361 aactgaccgc tcggcgcgtc gctgacagca acttcacagc cggtaaaggc gttcagttgg
    21421 gtgctgatgt ctgaaattcg ttcgcttttg gcctgcacga ccaggctgca aacttgccag
    21481 ttagtgtgca tggagatact ccgcagttat ggctgatacc ggacagctgg ctgcacatgc
    21541 tccacatccg ttgcaaagtt ggctattaag ttgcggctgg tagatcccgg agagcgtcgg
    21601 gcgaaagata attgccattg gctcacagct atcctgacag cggcggcatt caactgactg
    21661 atacgccagg cacgcgtccc caatggtgaa ctgcaaatcc caggccctgg tgtggcgcgg
    21721 agaaaatagc gattcggggc aagcctgcgc gcaggcgtaa cagaagctgc actcgttatt
    21781 tttgaaatta acgctcggat agctacccgc gccgcgttgc agaatgttgt tttcacaagc
    21841 attaatacag gcgtcgcagc gggtgcaatg ggtcagaaaa tgagattcat caccggacca
    21901 gggcggacgg ataccgttac tggctttgcg ccagcgacca gtgagtatgc cccgacggga
    21961 tgcatcaatc ttcacattga ccttccatca ttaacgcgct ctgaaaattg agagcgacca
    22021 aataaaccgc ataattaata agccattttt atagccgcta agatattaaa ggatgtgtca
    22081 aagatgcata ccccgatcgg ggtaaaacct gtagcaggat caaaagagtg gcgggaagcg
    22141 tggc
//
LOCUS       DAFGPF010000081        21910 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFGPF010000081 DAFGPF010000000
VERSION     DAFGPF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21910
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.081"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            141..1510
                     /locus_tag="LSX49_003419"
     CDS             join(141..621,621..1510)
                     /locus_tag="LSX49_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS150 family transposase"
                     /protein_id="HBL7169785.1"
                     /translation="MSKPKYPFEKRLEVVNHYFTTDDGYRIISARFGVPRTQVRTWVA
                     LYEKHGEKGLIPKPKGVSADPELRIKVVKAVIEQHMSLNQAAAHFMLAGSGSVARWLK
                     VYEERGEAGLRALKIGTKRNIAISVDPEKAASALELSKDRRIEDLERQVRFLETRLMY
                     PKKAESLSSSHEKVKVLNELRQFYPLDELLRAAEIPRSTFYYHLKALSKPDKYADVKK
                     RISEIYHENRGRYGYRRVTLSLHREGKQINHKAVQRLMGTLSLKAAIKVKRYRSYRGE
                     VGQTAPNVLQRDFKATRPNEKWVTDVTEFAVNGRKLYLSPVIDLFNNEVISYSLSERP
                     VMNMVENMLDQAFKKLNPHEHPVLHSDQGWQYRMRRYQNILKEHGIKQSMSRKGNCLD
                     NAVVECFFGTLKSECFYLDEFSNISELKDAVTEYIEYYNSRRISLKLKGLTPIEYRNQ
                     TYMPRV"
     gene            1611..1763
                     /gene="hokA"
                     /locus_tag="LSX49_003420"
     CDS             1611..1763
                     /gene="hokA"
                     /locus_tag="LSX49_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HBL7169786.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQENYELAAFL
                     ACKLKE"
     gene            complement(1951..2163)
                     /gene="cspA"
                     /locus_tag="LSX49_003421"
     CDS             complement(1951..2163)
                     /gene="cspA"
                     /locus_tag="LSX49_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HBL7169787.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(2444..2734)
                     /locus_tag="LSX49_003422"
     CDS             complement(2444..2734)
                     /locus_tag="LSX49_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HBL7169788.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            3168..3878
                     /locus_tag="LSX49_003423"
     CDS             3168..3878
                     /locus_tag="LSX49_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HBL7169789.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(3928..4902)
                     /gene="ghrB"
                     /locus_tag="LSX49_003424"
     CDS             complement(3928..4902)
                     /gene="ghrB"
                     /locus_tag="LSX49_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HBL7169790.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVALPHIGSATHETRYGMAACAVDNLINALQGKVEKNCVNPHVVD"
     gene            complement(5006..5665)
                     /locus_tag="LSX49_003425"
     CDS             complement(5006..5665)
                     /locus_tag="LSX49_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HBL7169791.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGSHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            5818..8151
                     /gene="bisC"
                     /locus_tag="LSX49_003426"
     CDS             5818..8151
                     /gene="bisC"
                     /locus_tag="LSX49_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin sulfoxide reductase"
                     /protein_id="HBL7169792.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSRGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALELIHHQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLARCTTGYA
                     VFASYLLGESDGIAKNAEWAAEICGVGAAKIRELAAIFHQNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRAAVLSSMQGSLPGGTDAVDK
                     IPVARIVEALENPGGAYQHNGMDRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRDEARNDF
                     DVFAELSERWEKGGYARFTEGKSELQWLETFYNVARQRGASQQVELPPFAEFWQANQL
                     IEMPENPDSERFIRFADFRRDPQAHPLKTASGKIEIFSQRIADYAYPDCPGHPMWLAP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQTRGIQD
                     GDTVRLWNSRGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTVTAFEPPASS"
     gene            complement(8120..8560)
                     /locus_tag="LSX49_003427"
     CDS             complement(8120..8560)
                     /locus_tag="LSX49_003427"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL7169793.1"
                     /translation="MIREAQRSELPALLELWLESTTWGHPFIKSSYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRHPHLML
                     EVYQKNQPAIDFYHAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(8557..9120)
                     /gene="tag"
                     /locus_tag="LSX49_003428"
     CDS             complement(8557..9120)
                     /gene="tag"
                     /locus_tag="LSX49_003428"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBL7169794.1"
                     /translation="MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFADFVWSFVNHQPQVTQATTLSEIPTSTPASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCHPGNKP"
     gene            9278..9976
                     /locus_tag="LSX49_003429"
     CDS             9278..9976
                     /locus_tag="LSX49_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312460.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7169795.1"
                     /translation="MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGHS
                     TERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYEQ
                     VTTGPVAALHYDGTTTSMYNEFGDSTTTLADPLWHASVSTLGWRVDSRLGDLRPWAQI
                     SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALSQAENTTN
                     NSDYLYTMGVSARF"
     gene            10205..11413
                     /locus_tag="LSX49_003430"
     CDS             10205..11413
                     /locus_tag="LSX49_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169796.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLGAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSNNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTHLLE
                     TVGLEKTFVIWGAIVLVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDAISAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVIALVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KMLREAHGSL"
     gene            11737..13428
                     /gene="eptB"
                     /locus_tag="LSX49_003431"
     CDS             11737..13428
                     /gene="eptB"
                     /locus_tag="LSX49_003431"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HBL7169797.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPVNAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAREAAAN"
     gene            13520..13596
                     /locus_tag="LSX49_003432"
     tRNA            13520..13596
                     /locus_tag="LSX49_003432"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13554..13556,aa:Pro,seq:cgg)
     gene            14340..15947
                     /gene="dppA"
                     /locus_tag="LSX49_003433"
     CDS             14340..15947
                     /gene="dppA"
                     /locus_tag="LSX49_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HBL7169798.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPKIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
     gene            16254..17273
                     /gene="dppB"
                     /locus_tag="LSX49_003434"
     CDS             16254..17273
                     /gene="dppB"
                     /locus_tag="LSX49_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HBL7169799.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            17283..18185
                     /gene="dppC"
                     /locus_tag="LSX49_003435"
     CDS             17283..18185
                     /gene="dppC"
                     /locus_tag="LSX49_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HBL7169800.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            18196..19179
                     /gene="dppD"
                     /locus_tag="LSX49_003436"
     CDS             18196..19179
                     /gene="dppD"
                     /locus_tag="LSX49_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBL7169801.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDKCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            19176..20180
                     /gene="dppF"
                     /locus_tag="LSX49_003437"
     CDS             19176..20180
                     /gene="dppF"
                     /locus_tag="LSX49_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HBL7169802.1"
                     /translation="MSTHEATPQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIETPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLTGELPSPLNPPPGCAFNARCRRRFGPCIQLQPQLKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(20210..21481)
                     /locus_tag="LSX49_003438"
     CDS             complement(20210..21481)
                     /locus_tag="LSX49_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HBL7169803.1"
                     /translation="MQHNTLPKHDQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLFYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASDFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYVTLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTRKINSRVLTLAICTFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     SQLEKLRGFKAWMILLYGILLCLSPLLKLIE"
BASE COUNT         5347 a         5325 c         5716 g         5522 t
ORIGIN      
        1 aagctggaat agccacgggt gcttgaggct gtttgtctca ggtattcacc gaaaggcaga
       61 cagagaaaag ccccacctga ctataaatca aagtgtactg cacccatttt gttggacgat
      121 gaaatggaat agcccctaat atgtcaaagc caaaataccc ttttgaaaag cgccttgaag
      181 tcgtgaatca ctacttcaca actgatgatg gttacaggat catctcggca cgttttggtg
      241 tcccccgaac ccaggtcagg acatgggttg ccctctatga aaaacatgga gaaaaaggtt
      301 taattcccaa acctaaaggc gttagtgctg atccagagtt gcgtattaag gtcgtgaaag
      361 ctgtgatcga gcagcacatg tcccttaatc aggctgctgc tcactttatg cttgctggta
      421 gtggttctgt agccaggtgg ctgaaggtct atgaagagcg cggagaagct ggtttacgcg
      481 cgctcaagat tggcaccaaa agaaacattg caatatcagt tgatccagaa aaagcggcat
      541 cagcattgga gctgtcaaaa gaccgacgca ttgaggatct tgaaaggcaa gttcgatttc
      601 ttgaaacgcg gcttatgtat ctaaaaaagc tgaaagcctt agctcatccc acgaaaaagt
      661 gaaagtactc aacgagctaa ggcagtttta tcctcttgat gagcttctca gggctgcgga
      721 gataccgcgc agtacgtttt attatcatct aaaggctctc agcaagcctg acaagtatgc
      781 ggacgttaaa aagcgtatta gtgagattta tcacgagaat agaggccgat acggataccg
      841 tagggtaacg ctgtctcttc atcgagaagg gaaacagatt aaccataaag ctgttcagcg
      901 cctgatggga accctctcac ttaaagcagc gattaaggtc aagcgatacc gctcttacag
      961 aggagaggta gggcaaaccg cccctaatgt tctccaaaga gatttcaagg ctacgcggcc
     1021 aaacgagaag tgggttaccg atgttactga atttgcagtc aatgggcgca agctgtattt
     1081 gtctccagta atagatctct tcaacaacga agttatttct tacagccttt cggaaagacc
     1141 agtgatgaac atggttgaga atatgctcga tcaggcattc aaaaagctta atcctcacga
     1201 gcatcctgtt ctgcactctg accagggatg gcagtatcgt atgagaagat atcaaaatat
     1261 ccttaaagaa catggtatta aacaaagcat gtccagaaaa ggcaattgtc tggataatgc
     1321 tgtggtggag tgtttctttg gaaccttaaa gtcggagtgt ttttatcttg atgagttcag
     1381 taatataagc gaactgaagg atgctgttac ggaatatatt gaatactaca acagcagaag
     1441 aattagcctg aaattaaaag gtctgactcc aattgaatat cggaatcaga cctatatgcc
     1501 tcgtgtttaa ctgtccaact ttttggggtc agtacaaagt gaggctaccc tatgcctgaa
     1561 caccataagg ttagcctctt actcgttgga aatcaacaca ggaggctggg atgccgcaga
     1621 aatatagatt actttcttta atagtgattt gtttcacgct tttatttttc acctggatga
     1681 taagagattc actgtgtgaa ttgcatatta aacaggagaa ttatgagctg gccgcgtttt
     1741 tagcctgcaa attgaaagag taagaatctt cggcgggaag ttattcccgc ctttcttacg
     1801 gcgttacgca ttctcattac acccaaattt attcttcaca aaaataataa tagattttat
     1861 tacgtgaccg attatttatt tcctgaaaaa caaataaaaa aatccccgcc aaatggcagg
     1921 gatcttagat tctgtgcttt taagcagaga ttacaggctg gttacgttac cagctgccgg
     1981 gcctttagcg ccgctttcga tggtgaagga cactttctga ccttcgtcca gagatttgta
     2041 accatcgttc tggatagcag agaagtgtac gaacacgtct ttagagccat cgtcaggagt
     2101 gatgaagccg aagcctttgt cagcgttgaa ccattttacg ataccagtca ttttaccgga
     2161 catagtgtat tacctttaat aattaattgt gcctttcggc gatatggcgt gctttacaga
     2221 ttttgaagcg ttaaaggaat gtgcactacg aggggtatca acgataactc ttgaagggac
     2281 ttgccttact acactgcttt aatggtctgt acgtcaaacc gttgatgtgc attaagccac
     2341 gcattggtgg gtgatgcaac aattattttt catatttatg attaatcggt tggaaaacgg
     2401 tcctgttatc aggaccgtaa acagaaataa agtggataaa agcctattcc atcaactgct
     2461 tacttaatgc cgggttggct tgaatcaaac gcatcaattt tagttcggca cttgaaggct
     2521 tcacgcgtct ggattcccat tcctttacca tggcgactga tacgcccaaa acccgggcga
     2581 aatcatcgat ttttaatcct gtcccttttc gtaactgctc aatttcggta caggacgttg
     2641 ttctgtgcgt cagggtaatt ttctgcgttt catctttaaa aacaatctgt tccaggctgc
     2701 tcaacagctc atgcattgga tctttatatt ccattgaaaa ctcctcaaat cacactgcgg
     2761 gatcgtgaat tgcatcgaag ctcattaaga atagtcggga aaaacagaca cagcggggtg
     2821 tagtcagggc atactctgac tatgattcga ttcagccagt catttagcgt gacttatagc
     2881 cacctaacga tctgataaat gccgatatat ctcttaccac tcccggtttg taaagatttc
     2941 gaaaatctaa cgttctgcga aggcgtaaat ctctggctac aaaaaaggca acggcaatat
     3001 cattttttaa caatgaaaca acaaattaac cttgtttcat tttctccatg attttaccag
     3061 gaagattatg tagaaagggt atcctgcaag cctgtcctgg actatccttg tcacgtcaga
     3121 cacgcgtgtg tcgttgtgcg ctttttttgg gtgaaaggag taagaaaatg gcgacaggaa
     3181 agtcctgctc tcgctggttt gcgcctcttg cggcgttatt aatggtagtt agcctgagtg
     3241 ggtgttttga taaagaaggc gatcagcgta aagcgtttat cgacttcctg cagaatacag
     3301 tgatgcgtag cggtgaacgt ctaccaaccc tgactgccga tcagaaaaaa cagtttggtc
     3361 cttttgtctc tgattacgcg attctgtatg gttattctca gcaggtgaat caggcgatgg
     3421 attccggtct gcgcccggtt gtagacagcg ttaacgcaat tcgcgtaccg caggattacg
     3481 ttacgcaaag cggtccgctg cgtgaaatga acggttcgct gggtgtgctg gcgcaacagc
     3541 tgcaaaatgc gaagttgcag gccgatgctg cgcactctgc gttaaaacag agtgatgacc
     3601 tgaaaccggt ctttgatcag gcattcacca aagtggtaac gacgccagct gatgcattgc
     3661 aaccgttgat tccggcggca caaactttca cgcaacaact ggtgatggtt ggagactaca
     3721 ttgctcagca aggtactcag gtgagctttg tcgcaaatgg catccagttc ccgacttcac
     3781 agcaggcaag tgaatataac aaactgattg cgccattacc ggcacaacat caggcgttta
     3841 atcaggcctg gactacagca gttactgcaa cccaataaag agtaaaagcc cgagcgatta
     3901 tcgggcttta ctcctcgcag tcgcggctta gtccacgacg tgcggattca cacagttctt
     3961 ctcaaccttt ccttgtaacg cattaatcaa attatccacg gcacaggcgg ccatgccata
     4021 acgcgtctca tgggtggcag atccaatatg cggtaatgcg acgacgttgg ccattgagag
     4081 caacggcgaa tctacggaca gtggctcttg ttcgaagaca tccagcccgg cggcgtgaat
     4141 ttcccctttc tgcaatgcag caatcagtgc attttcatca accaccgggc cacgtccggc
     4201 attaatgaaa atggcggagg atttcatttt ggcgaattgt tctgcgccaa acagatgatg
     4261 cgtctcatcc gttaacggca ggatcaggca aacgaaatct gactcttgta acagagtatc
     4321 caaatcgcag tagcgggcgt tgaagcgttc ttctgcttct ttatggtggc gacgcgcgtt
     4381 atagaggatg ggcatgttga agccaaagtg cgcacgttgt gccagcgcca tgccgatccg
     4441 tcccatcccg acaatgccca gtgttttatg gtgaacgtca gtgccgtacc agtccgggcc
     4501 tatactcgcg gtccattcgc ctgcttttac ccgttctgct acctccacaa cccgacgagc
     4561 ggtagacaac accagcgcca tcagcgtatc ggcgacggtt tctgttaata cggttggtgt
     4621 gtgcatcagc agaatttttc gggcggtaag cgcatcgaca tcaaaattgt catagccgac
     4681 ggagatcgtt gatgtggcac gcagtttcgg cattttttcc agcaatgcgg catcaacatt
     4741 ctcatttgaa cccagcaagc cttcagcttc ggcaaaaatt gctgcatttt gttcgacggt
     4801 ttgtgggctg aggtttgcta cctggtgaac ggtgaaatgt tcttgcaggc gttgcagtaa
     4861 atcatcaggt aaggctttgt agaggataac ggacggcttc atgcttctct ccattcactg
     4921 ataaggcgat caccttagcc tgaaatatga tgaaggaaaa ctgaagaatg ccaggtgatt
     4981 tctgcatcac ctgacatgaa agggattaca gtgggcttaa ggtaatttct acacggcggt
     5041 tttgcgcctt accttctgcg gtgctgttgc tggcgattgg gttagccggg ccaaggccct
     5101 gagtacggat gcggctggcg tccacgccct gggtgatcaa cgcgctggca acggaatccg
     5161 cacgctgctg ggagagacgc atgttcaggt cgtgactccc cgtgctgtcg gtataaccaa
     5221 tcacgttaac cgccgttttc ggatactctt tcagtaccat tgccacgccg gtcagggtgt
     5281 tagcgcccgc cggtttcagg gttgcgctgc tgctgtcgaa ggtcacattg ttcggcatat
     5341 tgaggataat gttatccccg ctgcgggtta cgctaacacc agtgccgcgc attttgtcac
     5401 gcagcttcgc ttcctgcaca tccatgtaat aaccaacgcc gccgcccaga gctgcgcctg
     5461 ctgctgcgcc aatgagcgcg cctttaccgc gatctttctt cgaagaagag agcgcaccaa
     5521 tacccgcgcc aacgagagag cccagacctg cgccgatagc agatttacct gcttcgcgtt
     5581 cgccggtgta agggttagtt gtacagccag ataccgccag agcgccactc actacggcgg
     5641 caataagata aacacgtttc ttcattgtta atccttaata acctttttat tctttgccac
     5701 gggttccgtg gcgggagatt atgccgcgtg agcatgaaga ttattcctgg gaatactcgg
     5761 aaatttgtaa gtaatattta actgctcaat acatctaacc tttcaggagt cttcggtttg
     5821 gccaactcat cctcacgata ttccgttctg actgccgccc actgggggcc tatgctggtt
     5881 gaaaccgacg gcgaaaccgt gtttagctcg cgtggcgcgt tagccacagg aatggaaaac
     5941 tccttgcaga gcgcggttcg cgaccaggtt cacagcaata cgcgggtgcg atttccaatg
     6001 gtgcgcaaag gctttcttgc gtcaccggaa aatccgcaag gcattcgtgg gcaggatgaa
     6061 tttgttcgcg tgagttggga tgaggcgctg gagcttattc accatcaaca taaacgcatt
     6121 cgtgaggctt atggtccggc atcgattttt gctggttcct acggctggcg ttcaaacggc
     6181 gtgctgcata aggcctcgac attattacaa cgctatatgg cgttggcagg cggttatact
     6241 gggcatctgg gggattattc gaccggcgcg gcacaggcga tcatgccgta tgtcgtgggt
     6301 ggcagcgaag tttatcaaca gcaaaccagt tggccgctgg tgctggaaca tagcgatgtc
     6361 gtggtgctgt ggagtgctaa cccactcaat acgctgaaaa ttgcgtggaa tgcatccgat
     6421 gagcaggggc tttcttactt ttccgcactg cgtgacagcg ggaaaaagct gatctgcatt
     6481 gatccaatgc gatcggaaac cgtcgatttc tttggcgata aaatggagtg ggtggcaccg
     6541 cacatgggca ccgatgttgc gttgatgctg gggatcgccc atacgctggt ggaaaatggt
     6601 tggcacgacg aagcgtttct ggcgcgttgc accacaggtt atgctgtctt cgcctcttat
     6661 ttgctgggcg agagtgacgg aatagcgaaa aacgccgaat gggcggcaga gatttgtggt
     6721 gttggcgcag cgaaaatccg cgagctggcg gctattttcc accaaaatac aaccatgctg
     6781 atggcaggct ggggaatgca gcgccaacag tttggtgagc aaaaacactg gatgatcgtc
     6841 acgctggcgg caatgttggg gcaaatcggc acacccggcg gcggttttgg tctttcttac
     6901 cattttgcca atggtggtaa ccccacgcgc cgcgctgcgg tgctctcttc catgcagggc
     6961 agcttgccgg gtggcaccga tgcggtagat aaaatccctg tcgcccgcat tgttgaagca
     7021 ctggaaaacc ctggtggcgc atatcaacat aacggtatgg accgacattt cccggatatt
     7081 cgttttatct ggtgggcggg tggtgccaac tttactcatc atcaggatac caatcgcctg
     7141 atccgtgcct ggcaaaaacc ggagctggtg gtgatctccg aatgcttctg gacggctgcg
     7201 gcgaaacacg cggatatcgt tctgcctgcg accacctctt ttgagcgtaa tgatctcacc
     7261 atgaccggtg attacagtaa tcagcatctg gtgccgatga agcaagtggt gccgccacgc
     7321 gatgaagcgc gtaatgattt tgatgttttt gccgagttga gtgaacgttg ggagaagggc
     7381 ggttatgcac gttttacgga aggaaaaagt gagctgcaat ggctggaaac gttttataac
     7441 gttgcccggc agcgcggggc aagccagcag gttgaattgc cgccatttgc tgagttctgg
     7501 caagccaacc agttaattga gatgccggaa aacccggaca gtgagcggtt tattcgcttc
     7561 gccgattttc gccgcgatcc gcaggcgcat ccattaaaaa ccgccagcgg taagattgaa
     7621 atcttctcgc agcgtattgc cgattacgct tatccggatt gcccggggca tccaatgtgg
     7681 ctggcgccgg acgaatggca gggtaatgcc gaaccggaac agttgcaggt actttctgct
     7741 catccggcgc atcgtctgca cagccagctg aattacagtt ctctgcgcga attgtacgcg
     7801 gtggcaaatc gtgagcctgt caccattcat cctgacgatg cccagacgcg cggcatacaa
     7861 gatggcgata ctgttcggct gtggaactca cgcgggcaaa ttcttgccgg cgcggtcatt
     7921 agcgagggaa ttaaacctgg cgtgatttgt attcacgaag gcgcatggcc ggatttggat
     7981 ttaaccgctg acggcatttg taaaaacggc gcagtgaacg tgctgaccaa agatctcccc
     8041 agctcgcggc tggggaatgg ctgtgcgggt aatacggcgc tggcatggct ggaaaaatac
     8101 aacggtccgg aactgacagt tacagcgttt gaaccaccgg ccagctcata atccaggtgg
     8161 gtagttgggt ttcatcctgc catgcgcaat cgacaatgtg aaaaccctgc gcatggtaga
     8221 aatctatcgc cggttgattt ttttgataaa cctccagcat cagatgggga tggcgctgct
     8281 gcacatactg catcagcgcc ttaccaatac cgcgcctgac ggccttcggt gcgacaaaca
     8341 ttgctgccag aaatcggcct tccataatgc tgacaaaacc gagaagctta ccgtcttctt
     8401 cccagaccca gttttgcgcg ttggcaagat acgcatcccg caccagcgga atgcagtcac
     8461 gccagtaact cgattttata aagggatgcc cccaggttgt actttccagc cacagttcga
     8521 ggagcgcggg gagttctgaa cgttgcgctt cccgaatcat ggtttatttc ccggatggca
     8581 acagcagcca accacatgat cattcaccag cccacatgcc tgcataaagg agtaacagat
     8641 tgtggtaccg acaaacttaa aaccacgttt ttttagtgcc ttagataggg cgtcggaggc
     8701 gggtgtagat gtggggattt cgctcaacgt tgtggcttgt gtcacctgtg gttgatgatt
     8761 gacaaacgac cagacaaagt cggcaaacgg ttcgccgttc tgttccattt gcaggtacgc
     8821 ccgcgcatta ccaataattg cctgaatttt cccacgatgg cggataatcc cggcgtcctg
     8881 taccagtctt tcgacatcct cttcctgcat tgcggcaact ttcaccggat cgaactgatg
     8941 aaagcatgcg cgatagtttt cgcgtttttt gaggacggtg atccacgata acccagcctg
     9001 ctgcccttcc aggcagatca tttcgaacag ttttttactg tcagtttcag gcacgcccca
     9061 ttcattatca tggtaggcaa tataaagcgg gtcctgactc acccagccgc aacgttccat
     9121 actttccctc gctatgtacc cgatcgtaaa aatttcagcc gcttttcttg acgcatcggt
     9181 gaaaaagtca atatttaata cagggctact atgcccgata tccttcatac aatgacaata
     9241 atattgccga attcggctct tccctggagt cgtgttaatg atcataaaaa aaagcggtgg
     9301 tcgctggcag ctaagcctgc ttgcgagcgt ggtaatcagt gccttttttc tcaacacagc
     9361 ttacgcctgg caacaagaat atatcgttga tacgcaaccc ggacattcca cagagcgtta
     9421 cacctgggat agcgatcatc aacctgatta caacgatatt ttgtcgcaac gtattcaaag
     9481 tagccaaagg gcgctgggac tggaagtcaa tctggcggaa gaaacccctg tggatgtgac
     9541 cagcagtatg agtatgggct ggaattttcc tttatatgag caggttacaa ccggcccggt
     9601 cgcggcatta cattacgatg gcacaaccac ctcgatgtat aacgagtttg gcgacagtac
     9661 taccacgctg gccgatccgt tatggcatgc cagcgtgagt accttaggct ggcgtgttga
     9721 ctcccggctt ggcgatctcc gaccctgggc gcaaatcagc tataaccagc aatttggcga
     9781 gaatatctgg aaggcgcaat caggcctgag ccggatgacg gcgacaaacc agaacggcaa
     9841 ctggctggat gtcaccgtag gcgctgatat gttgctcaat caaaatattg ctgcctatgc
     9901 tgcgctatct caggcagaaa ataccactaa caatagcgac tatctgtata cgatgggggt
     9961 tagtgccaga ttttaacgtt atagatacaa ttgaaaccca taaataacaa ctaatgtggc
    10021 gatagtgggg actaacttac taaataataa atttggcgaa taattgtcga gtcattcatt
    10081 cctgaactaa tgcatttcat tccgttctga tggcatttca tgccgttttt ccccaggcat
    10141 aaagcgcact tcgttatggt tgtcagcaga gatttttcct ttttattact gcaggaatac
    10201 tgccatgaca ccttcaaatt atcagcgtac tcgctggctg acactcatcg gtactatcat
    10261 tacccagttt gctctggggt cggtttatac ctggagtctg tttaacggtg cgctttctgc
    10321 caagctgggg gctcctgtaa gccaggttgc tttctctttc ggcttgttaa gtctggggct
    10381 ggcaatttcg tcttctgttg cgggcaaatt gcaggaacgt tttggtgtta aacgcgtcac
    10441 tatggcttcc ggcattttgc tgggattagg tttcttcctg acagcacatt ccaacaacct
    10501 gatgatgctg tggttaagcg ccggtgtgtt ggttggtctg gcggatggtg cgggttacct
    10561 gttgacgctc tctaactgcg tgaagtggtt tccggagcgt aagggactta tctctgcttt
    10621 tgctatcggt tcttatggtc tgggcagcct gggttttaaa tttatcgaca cgcacctgct
    10681 cgaaacggtg ggtctggaaa aaacctttgt tatttggggc gcgattgtac tggtgatgat
    10741 tgtctttggc gcaacgttaa tgaaagatgc gccgaagcag gaagtgaaaa ccagcaatgg
    10801 tgtggtggag aaggactaca ccctggcaga gtcgatgcgt aaaccgcagt actggatgtt
    10861 agcggttatg ttcctgactg cgtgcatgag tggtctgtat gtgattggtg tagcgaaaga
    10921 tatcgctcaa agtctggcgc atcttgatgc aatttccgca gccaatgctg tgacggttat
    10981 ttccatcgcc aacctttctg gtcgtctggt gctgggcatt ctgtctgaca aaatcgcccg
    11041 tatccgtgtt atcaccattg gtcaggtgat tgcgctggtg ggtatggcgg ccctgctgtt
    11101 tgcaccattg aatgcagtga cgttctttgc agcgattgcc tgtgtggcat ttaactttgg
    11161 tggcacgatt acggtgttcc cgtcactggt cagtgagttc ttcggcctca ataacctggc
    11221 gaaaaactac ggcgtcattt acctcggttt cggtatcggc agcatttgtg gttcgattat
    11281 cgcttcactg tttggcggat tctatgtgac tttctacgtg attttcgccc tgctgattct
    11341 gtcactggcg ctttctacga ccattcgcca gccagagcag aaaatgttgc gtgaggcgca
    11401 tggctccctt taatgctcag ccgtgagcta ctgggcttca gcttcagtgt gcatcaaacg
    11461 catcaacgaa atgtataaac aataacgcgt aaaatttggg ccagttaact ggcccttttt
    11521 actgcttttt gtaacgctaa agtctctttt caaacttgca tttttgtaaa tttgtgcttc
    11581 gtgcacactc tttccccaca ctttttccct ttgctgtggt ctacttattc gcgcgtgtag
    11641 attttactta tctgactacc tccgcacttt tcccctgcct ggcctgaaaa gccactaagc
    11701 agggtgttat cacctgtttg tccagggttt gtttgcatga gatacatcaa atcgattaca
    11761 cagcagaagc tgagcttttt gcttgcaatc tatattggcc tttttatgaa tggcgcggtt
    11821 ttttaccgcc gctttggcag ctatgcgcac gattttaccg tctggaaagg catttctgct
    11881 gttgttgaac tggccgccac cgtactggtg accttctttt tactgcgtct gctttcgctg
    11941 tttggccgcc gcagctggcg tattctggca tcgctggtgg tgctcttttc tgcaggtgcc
    12001 agctattaca tgaccttcct taatgtagtc attggttatg gcatcatcgc atccgtcatg
    12061 accaccgata tcgacctgtc aaaagaagtt gttggtctga actttattct ctggttaatc
    12121 gccgtaagcg cgttgcctct tatccttatc tggaataacc gctgtcgtta caccttgctc
    12181 cgacaactgc gaaccccagg gcaacgtatt cgcagcctgg cggtcgtcgt actggcaggt
    12241 attatggttt gggcaccgat tcgtttgctg gatatccagc agaagaaagt ggagagggcg
    12301 acaggtgttg atttgccgag ttatggcggc gtcgtcgcga actcttatct gccatcaaac
    12361 tggctttcgg cattaggtct ttatgcctgg gcgcgggtcg atgaatcttc cgataacaat
    12421 tctctcctta accctgcgaa gaagtttacg taccaggctc cacaaaacgt tgatgataca
    12481 tatgtcgttt tcattattgg tgaaaccacg cgctgggatc atatgggcat tttcggctat
    12541 gaacgcaata ccacaccgaa actggctcag gagaaaaatc tggcggcgtt ccgtggttac
    12601 tcctgtgata ctgcaaccaa actctcactg cgttgcatgt ttgtacgtca gggtggagca
    12661 gaagataatc cgcagcgcac attaaaagaa cagaacattt tcgcggtatt gaagcagtta
    12721 ggattcagtt ctgatctcta cgctatgcaa agcgaaatgt ggttctacag caatacgatg
    12781 gcggacaaca ttgcttatcg tgagcagatt ggtgcggagc cacgtaaccg tggcaaaccg
    12841 gtagatgata tgttgctggt agacgaaatg cagcaatcgc tggggcgcaa cccggatggt
    12901 aagcatctga tcattctgca taccaaaggc tcacacttta actacaccca gcgttacccg
    12961 cgcagctttg cgcagtggaa gccggaatgt attggtgttg atagcggctg taccaaagcg
    13021 cagatgatca actcatacga caactcggtg acctatgtgg atcactttat ttccagcgtg
    13081 attgatcagg ttcgcgataa gaaagcgatt gtgttctatg cagctgacca cggtgagtca
    13141 attaatgaac gcgagcacct gcacggcacg ccgcgtgaac tggcaccgcc ggaacagttc
    13201 cgtgtgccga tgatggtctg gatgtcggat aaatatctgg aaaatccggt caatgcgcag
    13261 gcatttgcgc agctgaaaaa agaagccgac atgaaagtgc cacgccgtca tgtagagctg
    13321 tacgacacca tcatgggttg tcttggctat acttcaccgg atggtggaat taacgaaaac
    13381 aacaactggt gccacatccc gcaggcaaga gaggcggcgg ctaactaaga ggcctgctga
    13441 ctttctcgcc gatcaaaagg cattttgcta ttaagggatt gacgagggcg tatctgcgca
    13501 gtaagatgcg ccccgcattc ggtgattggc gcagcctggt agcgcacttc gttcgggacg
    13561 aaggggtcgg aggttcgaat cctctatcac cgaccaaatt cgaaaagcct gctcaacgag
    13621 caggcttttt tgcatctgta actcatgagg aagagaaccc ccgggggcgg ggaggttcga
    13681 ctcgacgtag gcctgataag acgcaccagc gtcgcatcag gcaaatgtac cggcccattg
    13741 tcggatgcgg cgcgaccgcc ttatccgatc tacacaccac acatttccct gtcaaatttg
    13801 cgccccatat ctcactatcc attaacggat ttgtgacaga aaccattgtc tttttttata
    13861 tttgcttaaa tctttttttg cgttacttat ggctggcgct ggcattttcc gctgtgcgtt
    13921 ttagcgttca tggtattaat cgctcagata tccaccttta cctcagattt ttttcattaa
    13981 atgcataaaa cttaatcacc aaatgttgct aaatattaag ctgattgttc tggttgtgtt
    14041 ggcgtagcac aaatttctct gctgcaaata gctgtttgaa gtttttttaa tctttgtttg
    14101 tggattctca ccgttggtgt aaatcccggt tggctgtatt gacgttttca cattctgttg
    14161 acagattgta ggtcacgagg ggcattttat ggaggatccg cactgttaca ctgatgttaa
    14221 ttagtacggc atccccacct cataacgttg acccgaccgg gcaaaaaaca aaaaaggtca
    14281 ggcagcgaca acccactgca aagggttaaa acaacaaaca tcacaattgg agcagaataa
    14341 tgcgtatttc cttgaaaaag tcagggatgc tgaagcttgg tctcagcctg gtggctatga
    14401 ccgtcgcagc aagtgttcag gctaaaactc tggtttattg ctcagaagga tctccggaag
    14461 ggtttaaccc gcagctgttt acctccggca ccacctatga cgcctcttcc gtaccgcttt
    14521 ataaccgtct ggttgaattt aaaatcggca ccactgaagt catcccgggc ctcgctgaaa
    14581 agtgggaagt cagtgaagac ggtaaaacct ataccttcca tctgcgtaaa ggtgtgaagt
    14641 ggcacgacaa taaagaattc aaaccgacgc gcgaactgaa tgccgatgat gtagtgttct
    14701 cgttcgatcg tcagaaaaac gcgcaaaacc cgtaccataa agtctctggc ggcagctacg
    14761 aatacttcga aggcatgggc ttgccagagc tgatcagcga agtgaaaaag gtggacgata
    14821 acaccgttca gtttgtgctg actcgcccgg aagcgccgtt cctcgctgac ctggcaatgg
    14881 acttcgcctc tattctgtca aaagaatatg ctgacgcgat gatgaaagcc ggtacaccgg
    14941 aaaaactgga cctcaaccca atcggtaccg gcccgttcca gttacagcag taccagaaag
    15001 attcccgtat tcgctataaa gcgtttgatg gctactgggg caccaaaccg aagatcgata
    15061 cgctggtctt ctctattact cctgacgctt ccgtgcgtta cgcgaaattg cagaagaacg
    15121 aatgccaggt gatgccgtac ccgaacccgg cagatatcgc ccgcatgaag caggataaat
    15181 ccatcaacct gatggaaatg ccggggctga acgtcggtta tctctcgtat aacgtgcaga
    15241 aaaaaccact ggatgacgtg aaagttcgcc aggctctgac ctacgcggtg aacaaagacg
    15301 ccatcatcaa agcggtttat cagggcgcgg gcgtatcagc gaaaaacctg atcccgccaa
    15361 ccatgtgggg ctataacgac gacgttcagg actacactta cgatcctgaa aaagcgaaag
    15421 ccttgctgaa agaagcgggt ctggaaaaag gtttctccat cgacctgtgg gcaatgccgg
    15481 tacaacgtcc gtataacccg aatgctcgcc gcatggcgga gatgattcag gcagactggg
    15541 cgaaagtggg cgtgcaggcc aaaatcgtca cctacgaatg gggtgagtac ctcaagcgtg
    15601 cgaaagatgg cgagcatcag acggtaatga tgggctggac tggcgataac ggggatccgg
    15661 ataacttctt cgccaccctg ttcagctgcg ccgcctctga acaaggctcc aactactcaa
    15721 aatggtgcta caaaccgttt gaagatctga ttcaaccggc gcgtgctacc gacgaccaca
    15781 ataaacgtgt tgaactgtac aaacaagcac aggtcgtgat gcacgatcag gctccggcac
    15841 tgatcatcgc tcactccacc gtgtttgaac cggtacgcaa agaagttaaa ggctatgtgg
    15901 ttgatccatt aggcaaacat cacttcgaaa atgtctctat cgaataatta aagccataca
    15961 agactgatgg caaaggcaaa actgcctgat gcgctccgct tatcaggcct acgaaaactc
    16021 tgcaatgtat tgagtttgca cgattttgta ggtcggataa ggcgtttgcg ccgcatccgg
    16081 cataaacaaa gcgctctttg tcaacaatct gcatacccgg tggcgctgtg cctctgcgtg
    16141 cagcgccatc cggcagcaat acttcattcc ctgtcccaca agggcgggaa ttgatttgtg
    16201 agcaatacag acacgcagtt ccaggctgcg ggtcactata gagaatccgg gttatgttgc
    16261 agtttattct ccgacgtttg ggactcgtca tccccacgtt tatcggtatt acccttctca
    16321 catttgcctt tgtccacatg atcccgggcg atccggtgat gatcatggcg ggcgaacgtg
    16381 ggatctcccc agagcgtcac gcgcaattgc tggctgaact cggcttagat aaaccgatgt
    16441 ggcagcagta tctccattac atttggggcg taatgcacgg tgatttaggc atttccatga
    16501 aaagccgaat tccggtatgg gaagagttcg tgccgcgctt tcaggccacg ctggaacttg
    16561 gcgtctgcgc gatgattttt gcgaccgcag tcgggattcc ggttggtgtg ctggctgcgg
    16621 ttaaacgtgg ttccattttc gatcacacag cggttggcct ggcgctgacc ggctactcga
    16681 tgccaatttt ctggtggggc atgatgttga tcatgctggt ttcggtgcac tggaacctga
    16741 cgcctgtctc cggtcgcgtg agcgacatgg tgttcctcga tgattccaat ccgttaaccg
    16801 gttttatgct gatcgacacc gccatctggg gtgaagacgg taactttatc gatgccgtcg
    16861 cccatatgat cctgcccgcc attgtgctgg gtactattcc gctggcggtc attgtgcgta
    16921 tgacgcgctc ctcgatgctg gaagtgctgg gcgaagatta tatccgcacc gcgcgtgcca
    16981 aaggtcttac ccggatgcgg gtgattatcg tccatgcgct gcgtaacgcg atgctgccgg
    17041 tggtgaccgt tatcggcctg caggtgggaa cattgctggc gggggcgatt ctgactgaaa
    17101 ccatcttctc gtggccgggt ctggggcgct ggttgattga cgcactgcaa cgccgcgatt
    17161 atccggtagt gcagggcggc gtattgctgg tggcgacgat gattatcctc gtcaacctgc
    17221 tggtcgatct gctgtacggc gtggtgaacc cgcgtattcg tcataagaag taagggggca
    17281 tcatgtcaca ggttactgaa aataaagtga ttagcgcacc ggtgccgatg accccgttac
    17341 aggagttctg gcactatttt aaacgcaaca aaggcgcggt tgtcgggctg gtttacgtcg
    17401 tcatcgtgct gtttatcgcg atctttgcca actggattgc accctataac ccagcggaac
    17461 agttccgcga tgcactgctt gccccgcctg cctggcagga aggcggcagc atggcgcact
    17521 tgctgggcac tgatgacgtg gggcgtgatg tgctgtcgcg gctgatgtac ggcgcgcgct
    17581 tgtcgctgct ggttggctgt ctggtagtgg tgttatcgct gattatgggc gttattctcg
    17641 gcctgatcgc tggttacttt ggcggtctgg tcgataacat catcatgcgc gtggtcgata
    17701 tcatgctggc gctgccaagt ctactgctgg cactggtgct ggtggcgatt ttcggcccgt
    17761 cgattggtaa cgccgcgctg gcgctaacct tcgttgcgct gccgcattat gtgcgcttaa
    17821 cccgcgccgc cgtgctggtg gaagttaacc gcgattacgt caccgcgtct cgcgtggcgg
    17881 gtgccggggc aatgcgccag atgtttatta acatcttccc gaactgcctt gcgccgctga
    17941 ttgttcaggc gtcgctcggt ttctctaacg ccattctcga tatggctgct cttggtttcc
    18001 tcggcatggg cgcgcagccg ccaacgccgg agtggggcac catgctctct gacgtgttgc
    18061 agttcgcgca aagcgcctgg tgggtcgtga ccttcccggg tctggcgatc ctgctgacgg
    18121 tgctggcatt taacctgatg ggtgacggtc tgcgtgacgc gctcgatccc aaactgaagc
    18181 agtaagaggt tcgagatggc gttattaaat gtagataaat tatcggtgca tttcggcgac
    18241 gaaagcgcac cgttccgcgc tgtagaccgc atcagctaca gcgtaaaaca gggtgaagtg
    18301 gtcgggattg tgggtgagtc cggctctggt aaatcggtca gttcgctggc gattatgggg
    18361 ctgattgatt atccgggccg cgtaatggcg gaaaagctgg agtttaacgg tcaggatttg
    18421 cagcgtatct cagaaaaaga gcgccgcaac ctggtgggtg ccgaagtggc aatgatcttc
    18481 caggacccga tgaccagcct taacccgtgc tacaccgtgg gtttccagat tatggaagcg
    18541 attaaggtgc atcaaggcgg caacaaaagt acccgccgtc agcgagcgat tgacctgctg
    18601 aatctggtcg gtattcccga tccggcatcg cgtctggatg tttacccgca tcagctttcc
    18661 ggcggcatga gccagcgcgt gatgatcgcc atggcgattg cctgtcggcc aaaactgctg
    18721 attgccgatg aaccaaccac tgcgctggac gtgaccattc aggcgcaaat tatcgaactg
    18781 ctgctggagc tacagcagaa agagaacatg gcgctggtgt taattaccca tgacctggcg
    18841 ctggtggcgg aagcggcaca taaaattatc gtgatgtatg caggccaggt agtagaaacg
    18901 ggcgatgcgc acgctatctt ccatgcgccg cgtcacccgt atactcaggc attgctgcgt
    18961 gcgctgccgg aatttgctca ggacaaagaa cgtctggcgt cgttgccagg tgtcgttccc
    19021 ggcaagtacg accgcccgaa cggctgcctg cttaacccgc gctgccccta cgccactgac
    19081 aaatgccgtg ctgaagaacc ggcgctgaat atgctcgctg acgggcgtca gtccaaatgc
    19141 cattacccac ttgatgatgc cgggaggccg acactatgag tacgcatgag gccaccccgc
    19201 aacaaccgct gttgcaggct atcgacctga aaaaacatta tccggtgaag aaaggcatgt
    19261 tcgcgccgga acgtctggtg aaggcgctgg atggcgtttc gtttaacctt gaacgtggca
    19321 aaacgctggc agtagtaggt gaatctggct gcggtaaatc gaccctaggt cggttgctga
    19381 cgatgattga aacgcccacc ggcggcgaac tgtattacca ggggcaggat ctgctcaagc
    19441 acgatccgca ggcgcagaag ctacgtcggc agaaaatcca gattgtcttc cagaaccctt
    19501 acggttcgct gaatccgcgt aaaaaagttg ggcagattct cgaagagccg ctgctgatca
    19561 acaccagctt aagcaaagaa cagcgtcggg aaaaagccct gtcgatgatg gcgaaagtcg
    19621 gcctgaaaac cgagcattat gaccgctatc cgcatatgtt ctccggcggt cagcgtcagc
    19681 gtatcgccat tgcccgaggt ctgatgctcg acccggatgt ggtgattgcc gatgagccgg
    19741 tttccgcgct ggacgtctca gtgcgtgcgc aggtgctgaa tctgatgatg gatttgcagc
    19801 aggaactggg gctatcttat gtctttatct cgcacgatct gtcggtggtg gagcacattg
    19861 ctgatgaagt gatggtgatg tacctgggcc gctgcgtgga gaaggggacg aaggaccaaa
    19921 tcttcaataa cccgcgccac ccgtacactc aggcgctgct ctccgcgaca ccacgcctga
    19981 acccggacga tcgtcgcgaa cgcatcaaac ttaccggtga actgccaagc ccgctgaatc
    20041 caccgccagg ctgcgccttc aacgcccgct gtcgtcggcg cttcggcccc tgcatccagt
    20101 tgcagccgca gctaaaagac tacggcggtc aactggtagc ttgttttgcc gttgatcagg
    20161 atgaaaatcc gcagcgttaa ctcacaaaac cggggccatg cgctccggtt tactcaatca
    20221 acttcaacag tggcgacaag cataacaaaa tgccgtacag cagaatcatc caggctttaa
    20281 acccgcgaag tttttccagt tgtgagactt tatagatcag gaaaaacgga atgaggcacg
    20341 acacaatgcc atataacggg cttcccaact gaaagaacac cagtaccgat acacgaaacg
    20401 aaacccaaat cgtcaacgta atgacgataa aagtgcagat cgccagagtc agcacgcgtg
    20461 agttaatttt cctggtatca ataattcggc ttaacagatt gagaataatg cctttaatgg
    20521 cctcgtggaa accgagataa atgccaaaga atgcagtcag tacggcaaag atattcagca
    20581 ccgtagaggt gatatgaatg atatgcccag ggatcacctg cgcggccagt gccagtgccg
    20641 agatattttg ttcaaaggca gaaacggctt cttcgtggct aattgagaag gtaaacgaaa
    20701 aggcaaaaaa caggatcacc gcgatgagcg tgacataact aattcggtgg gtacgcagcg
    20761 cgagccgggt tgccagtact ttatccgctt cccgtttacg ataggcaata ttcattgggt
    20821 taagtacctg aataaatacc gcggaaaaga agcaaaatgg aatagtaagc aggacatcgc
    20881 ggaaaaagtc ggaggcttgc gggaaggcgg ttatattggc gaaattccag tgcgggatca
    20941 tcgcaaaacc gaacacgaca ataatcccta ctttgaccac caccattggt ccggaaatct
    21001 taaacagtaa tcgttcacca ccagacgcaa tcgccaccag tacggcgaaa atggcgactt
    21061 tataaaatag agattgagaa agatcggcat cggttaaacc gaaggttttc aggtacgagg
    21121 cgctgtcgaa aaccacggag agagagtaga taaaaatccc gtggataatc atcaaaaagt
    21181 agataacccc gaggaaaatt ccccagttct tccccaggta atgactgata atatcggtgt
    21241 agtcattaca ggaatcgctt tcagaaaggg tttttaaata aatgtcctgt actacccagg
    21301 tggcaggata agcaatgatc gctgcggtaa taaataccca aattcccttc aagccaattt
    21361 gtactggcat cagcacggtt ccggcaccaa tcgccatgcc tatgcataat aaaacccagc
    21421 cgaagtcgta gcgtgtaaac ggcaatttct gatcgtgttt cggtagtgtg ttgtgctgca
    21481 taaagtcctg tccagaaaga agtcggcctc gcaaaaatga ataaacccag tttctcttgc
    21541 gcaacaggtg gagaagtcga atacgcagta tgtaaaaaat gaggcaacag attcactggg
    21601 gaggtcgcga ggaggcgcaa ttctacaaaa ttgcgcattt cactactagt ctggagtcag
    21661 cccggatatg agctgcaact attgcaaata aagaaattaa gctggaaggc atcacgcaat
    21721 gaggaagatt gccgggtgct gacggcaaaa agcaatcgta aaatcagcgg caagccggaa
    21781 gggttccggt gaggcgcaat gttgcggggg ctttatccct ggtggcattg gttgctggag
    21841 agagaaaacc cccgcacgtt gcaggtatgc acctgacaac atcacggggg ccattcttgc
    21901 atctagacca
//
LOCUS       DAFGPF010000082        21855 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFGPF010000082 DAFGPF010000000
VERSION     DAFGPF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.082"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..411)
                     /locus_tag="LSX49_003439"
     CDS             complement(<1..411)
                     /locus_tag="LSX49_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HBL7169804.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFIPTLILVMMLIDLGAFVGTQGENKYGKDTQDVK"
     gene            512..1111
                     /locus_tag="LSX49_003440"
     CDS             512..1111
                     /locus_tag="LSX49_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HBL7169805.1"
                     /translation="MKPGCTLFILLCSALTVTTTAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQITWLPIQGPEQKAAKAKAQAYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            1219..1986
                     /gene="tpiA"
                     /locus_tag="LSX49_003441"
     CDS             1219..1986
                     /gene="tpiA"
                     /locus_tag="LSX49_003441"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBL7169806.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(2041..2796)
                     /gene="cdh"
                     /locus_tag="LSX49_003442"
     CDS             complement(2041..2796)
                     /gene="cdh"
                     /locus_tag="LSX49_003442"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HBL7169807.1"
                     /translation="MKKAGLLFLVMIVIAVVTAGIGYWKLTGEESDTLRKIVLEQCLP
                     NQQENQNPSPCAEVKPNAGYVVLKDRHGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSQKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(2903..3892)
                     /gene="sbp"
                     /locus_tag="LSX49_003443"
     CDS             complement(2903..3892)
                     /gene="sbp"
                     /locus_tag="LSX49_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter
                     substrate-binding protein Sbp"
                     /protein_id="HBL7169808.1"
                     /translation="MKKWGVGLTFLLVATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGGTFDQISKR"
     gene            complement(4212..5174)
                     /gene="pfkA"
                     /locus_tag="LSX49_003444"
     CDS             complement(4212..5174)
                     /gene="pfkA"
                     /locus_tag="LSX49_003444"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL7169809.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(5355..6257)
                     /gene="fieF"
                     /locus_tag="LSX49_003445"
     CDS             complement(5355..6257)
                     /gene="fieF"
                     /locus_tag="LSX49_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709720.2"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HBL7169810.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLVSPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(6406..6906)
                     /gene="cpxP"
                     /locus_tag="LSX49_003446"
     CDS             complement(6406..6906)
                     /gene="cpxP"
                     /locus_tag="LSX49_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HBL7169811.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            7056..7754
                     /gene="cpxR"
                     /locus_tag="LSX49_003447"
     CDS             7056..7754
                     /gene="cpxR"
                     /locus_tag="LSX49_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HBL7169812.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALSLNPGRQEATFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            7751..9124
                     /gene="cpxA"
                     /locus_tag="LSX49_003448"
     CDS             7751..9124
                     /gene="cpxA"
                     /locus_tag="LSX49_003448"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HBL7169813.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTV
                     NFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(9295..9969)
                     /gene="yiiM"
                     /locus_tag="LSX49_003449"
     CDS             complement(9295..9969)
                     /gene="yiiM"
                     /locus_tag="LSX49_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HBL7169814.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTDLGLEGDEQ
                     AEKKIHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYIGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGLVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSVAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(10118..11101)
                     /gene="kdgT"
                     /locus_tag="LSX49_003450"
     CDS             complement(10118..11101)
                     /gene="kdgT"
                     /locus_tag="LSX49_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HBL7169815.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK"
     gene            complement(11361..11981)
                     /gene="sodA"
                     /locus_tag="LSX49_003451"
     CDS             complement(11361..11981)
                     /gene="sodA"
                     /locus_tag="LSX49_003451"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HBL7169816.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQAYVNNANAALE
                     SLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVQKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPIVGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            12266..13300
                     /gene="rhaT"
                     /locus_tag="LSX49_003452"
     CDS             12266..13300
                     /gene="rhaT"
                     /locus_tag="LSX49_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HBL7169817.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIV
                     SWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFY
                     AWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVA
                     ANIVGIGMAN"
     gene            complement(13297..14163)
                     /gene="rhaR"
                     /locus_tag="LSX49_003453"
     CDS             complement(13297..14163)
                     /gene="rhaR"
                     /locus_tag="LSX49_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HBL7169818.1"
                     /translation="MAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDF
                     CELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKL
                     NLDWQGAIPGFSASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVSFANEMAELLFGQ
                     LVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQ
                     FRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMT
                     PSQWRHLNSQKD"
     gene            complement(14219..15055)
                     /gene="rhaS"
                     /locus_tag="LSX49_003454"
     CDS             complement(14219..15055)
                     /gene="rhaS"
                     /locus_tag="LSX49_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HBL7169819.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQEQDGQYPSHWRVNHCVLQQVRQLVAQLEQQEEGNDLPSTASREILFMQLLLLLRKS
                     SLQESVENSASRLNLLLAWLEDHFADEVNWDAVAAQFSLSLRTLHRQLKQQTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            15343..16812
                     /gene="rhaB"
                     /locus_tag="LSX49_003455"
     CDS             15343..16812
                     /gene="rhaB"
                     /locus_tag="LSX49_003455"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBL7169820.1"
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWNVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQHGQRVGLPVAY
                     RDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTIYQLRALTEQQPELIPHIAHALLI
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINP
                     NDDRFINPDEMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
     gene            16809..18068
                     /gene="rhaA"
                     /locus_tag="LSX49_003456"
     CDS             16809..18068
                     /gene="rhaA"
                     /locus_tag="LSX49_003456"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBL7169821.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDRIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNP
                     AHHIDAVESKLFGIGAESYTVGSNEFYLGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLLDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLENVRTYEKKILSRRG"
     gene            18335..19159
                     /gene="rhaD"
                     /locus_tag="LSX49_003457"
     CDS             18335..19159
                     /gene="rhaD"
                     /locus_tag="LSX49_003457"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBL7169822.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAP
                     YHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
                     FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSG
                     PTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGQRFGVTPLASALAL"
     gene            19169..19483
                     /gene="rhaM"
                     /locus_tag="LSX49_003458"
     CDS             19169..19483
                     /gene="rhaM"
                     /locus_tag="LSX49_003458"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBL7169823.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFATIEIESEERWNAVASTDVCQRWWKYMTDVMPANADNSPVSSELQEVFY
                     LP"
     gene            complement(19524..20918)
                     /locus_tag="LSX49_003459"
     CDS             complement(19524..20918)
                     /locus_tag="LSX49_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HBL7169824.1"
                     /translation="MKKSTLSLAIGLLLACSTGMAKTQHLTLEQRMALLEERLEAAEM
                     RAAKAEGQVKQLQTQQAAEIREIKTAQGNTPVNGQSTTESEKKNATPPNLLLSGYGDL
                     KIYGDVEFNMDAESNHGLLAMTNADVNSDPTNEQWNLNGRILLGFDGMRKLDNGYFAG
                     FSAQPLGDMHGSVNIDDAVFFFGKENDWKVKVGRFEAYDMFPLNQDTFVEHSGNTAND
                     LYDDGSGYIYMMKEGRGRSNAGGNFLVSKQLDNWYFELNTLLEDGTSLYNDGNYHGRD
                     MEQQKNVAYLRPVIAWSPTEEFTVSAAMEANVVNNAYGYTDSKGNFVDQSDRTGYGMS
                     MTWNGLKTDPENGIVVNLNTAYLDANNEKDFTAGINALWKRFELGYIYAHNKIDEFSG
                     VVCDNDCWIDDEGTYNIHTIHASYQFANVMDMENFNIYLGTYYSILDSDGDKIHGDDS
                     DDRYGARVRFKYFF"
     gene            complement(21272..>21855)
                     /locus_tag="LSX49_003460"
     CDS             complement(21272..>21855)
                     /locus_tag="LSX49_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HBL7169825.1"
                     /translation="YFFINKTRVVALMPALQPIDGVAVSYIDAAVALGNTINEMDKYY
                     TQENYKDDAFAKGKTFHYYSLAVMISAKQINNLISQDKFDAEAAMKKVSELETLVAQA
                     KEADKSGMNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMAEDSFP
                     RALCDYNEMVDEIFQLIVIAGRVCDEHGYVTKS"
BASE COUNT         5469 a         5706 c         5360 g         5320 t
ORIGIN      
        1 cttcacatcc tgggtatctt taccatattt attttcgcct tgtgtgccaa caaacgcacc
       61 aagatcgata agcatcatca ccagaatcag tgttgggata aaacgcccca ccgcccattg
      121 ccataccccc ggcaaaattg cccagttacc cgccagcagc atccacgcca caatcatcag
      181 aaatgcccat gcgccggaac gcccgcgatc atgcaagcgc ttaacggtta ctgccgctgt
      241 tggccaaagc aagcacacaa ggcaaaacgc cgcggtctga atatcgagta aatttttacc
      301 cgccagtgag aaaagcacca gcatgcctgc gaaccacagg cctatccaaa tccagaaatc
      361 acggcgtcca atacgccctt taaatgagaa taaccattgc tgtatggtca tgtaagttcc
      421 ttgatggttg tcttttccag gattctaccc ttttgacaag ggcgacagat atcgttttaa
      481 tcggagccag tcataacaaa aggtactgtc aatgaagcca gggtgtacgc tgtttattct
      541 cttatgttct gcattaaccg ttacaacaac ggcgcatgca caaacaccag atacggcaac
      601 gaccgcgcct tatctgctgg ctggagcccc tactttcgat ctctccatca gccagtttcg
      661 agaagacttt aacagccaga atcccagcct gccactgaac gaatttcgtg ccatcgacag
      721 cagtcccgac aaagccaatc tcactcgtgc agcaagtaaa attaacgaga acttgtatgc
      781 ttctactgcg ctggagcgcg gtaccttaaa aatcaaaagc attcaaataa cctggctacc
      841 catccagggg ccagagcaaa aagccgcgaa agcgaaagct caggcataca tggcagcggt
      901 gatccgcaca ctcaccccat taatgaccaa aactcaaagc cagaaaaaac tgcagtcgct
      961 actaacggcg gggaaaaaca aacgttatta caccgagaca gaaggtgcac tgcgttatgt
     1021 tgtcgcggac aacggcgaaa aggggctgac cttcgctgtt gaaccgatta agctggcgct
     1081 atctgaatcg cttgaaggtt tgaataaatg acaaaaagca aagcctttgt gccgatgaat
     1141 ctctatactg tttcacagac ctgctgccct gcggggcggc catcttcctt tattcgctta
     1201 taagcgtgga gaattaaaat gcgacatcct ttagtgatgg gtaactggaa actgaacggc
     1261 agccgccaca tggttcacga gctggtttct aacctgcgta aagagctggc aggtgttgct
     1321 ggctgtgcgg ttgcaatcgc accaccggaa atgtacatcg atatggcgaa gcgtgaagct
     1381 gaaggcagcc acatcatgct gggtgcgcaa aacgtggacc tgaacctgtc cggcgcattc
     1441 accggtgaaa cctctgctgc tatgctgaaa gacatcggcg cacagtacat catcatcggc
     1501 cactctgaac gtcgtactta ccacaaagaa tctgacgaac tgatcgcgaa aaaattcgcg
     1561 gtgctgaaag agcagggtct aactccggtt ctgtgcatcg gtgaaaccga agcggaaaac
     1621 gaagcgggca aaactgaaga agtttgtgca cgtcagatcg acgcggtact gaaaacccag
     1681 ggtgctgcgg cattcgaagg tgcggttatc gcttacgaac ctgtatgggc aatcggtact
     1741 ggcaaatctg caactccggc tcaggcacag gctgttcaca aattcatccg tgaccacatt
     1801 gctaaagttg acgctaacat cgctgaacaa gtgatcattc agtacggcgg ctctgtaaac
     1861 gcgtctaacg ctgcagaact gtttgctcag ccagacatcg acggcgcgct ggttggcggt
     1921 gcttctctga aagctgacgc tttcgccgtg atcgttaaag ctgcagaagc ggctaaacag
     1981 gcttaagtct gacaggtgcc ggatttcata tccggcactt actttcctaa actcctcgcc
     2041 ttaacgcaaa atctcacact gatgatcctg gatttcttcg gctgaagcac ggttcagcgt
     2101 cagtagattt cgttgtgtcg ccagcaatac aaatgagtta tcactctgcc gtaccatcgc
     2161 cagcccgtag cttcccatat gttcccgcgc ctcaggcact tcttccgcca gcatcataaa
     2221 tgggctgcgt tgtaccagtt cgctttccgt tacccgacgc gccaggtact catgcccacg
     2281 caaaccacct ggcagtggca accagcggct actgatgttc gccagattgt tatccagctg
     2341 ttcgcgcaca tcaggacgaa tacaagaaat atgaatatga aaatggtttt gcgtacgccc
     2401 ggtgcgggag ttgatcgcca gagataccgc gcgatcggga acaggctggc cgtatttttg
     2461 gctcataaaa tcacgcgcct gccaggctaa ccagaaaaaa ttaggcgttg acggatcggt
     2521 caacaatggg ctttcagtac cgttaatacg gtacgttggc attaacagat attgcagtgg
     2581 gccatgacga tcttttaaaa ccacgtatcc ggcgttgggt ttgacttccg cacatggcga
     2641 cgggttttgg ttttcctgct ggttgggcaa acattgctca agaactatct tacgtaacgt
     2701 gtctgactct tcaccggtta atttccagta accaataccg gcagtcacaa cggcgataac
     2761 tatcatcacc aaaaaaagaa gacccgcttt tttcatcttt ttttccctgt acctcaaaga
     2821 gatgcaaggg taacgcaaaa tcgtgacaaa taaaaaaccc agtggcgaga aaccaccggg
     2881 cttgataatt atcctgggga aatcagcgtt tgctgatctg atcgaacgta ccgccgttag
     2941 caaaatgctc tttttgcgct ttcgtccagc cgccgaactc ttcatcaatg gtgaataact
     3001 tcaattttgg aaacgcattt tcgtactttt tcgctacctc agcgtcgcgc ggacggtagt
     3061 agtttttcgc tgcaatttcc tgaccttctg gcgagtagag atatttcagg taggcttccg
     3121 ccacctcttt ggtgcctttt ttctcgacca ctttatcgac caccgacacg gttggctctg
     3181 cgaggataga ctcactcggc gtgacgattt cgaatttatc tttccccagt tcattcgctg
     3241 ccagcagagc ttcgttttcc caggcaatca gtacatcgcc aattccgcgc tcgacaaaag
     3301 tgttagtgga tccacgcgcg ccagaatcca gaacttcgac gtttttatac agtgcccgaa
     3361 caaaatcctg tgcttttgcc tgatcgttgt tgttgtgatg aagcgcgtag ccccaggctg
     3421 ccaggtaatt ccagcgcgcg ccaccagagc ttttcggatt aggcgtgatc accgaaacac
     3481 ccggtttaat cagatcgttc cagtcatgga tctgcttcgg attaccctta cgtaccagga
     3541 aaacaatggt ggaagtgtac ggtgcggagt tatccggcag acgtttgatc cactctttat
     3601 caatccgccc gcgttccgca attgcgtcca cgtcataggc cagagccagc gtgacaacat
     3661 cagcttcaat accgttgatt accgacgtcg cttgtttgcc tgaaccaccg tgtgactgac
     3721 gaatcaccac gttatcgcca gtttgctgtt tccagtgggc gctgaatgcc ttgttgtact
     3781 gttcgtacaa ttcgcgcgtt ggatcatatg aaacgttaag aagctgaata tcctttgcca
     3841 taacgctggt tgccaccagc aaaaatgtta accctacgcc ccactttttc atcgcccgac
     3901 tctcttatgt tgtgttgtga tgagcaaagc gtgccagaag gttgaccaaa cattaaagaa
     3961 taaaaaaaga tttgctataa cttgcgagta tatgttgggg gattaaaaag gcggaagaaa
     4021 tccgcctcat attgctgaca aagtgcgctt tgtccatgcc ggatgcggca caaacgcctt
     4081 atccggccta caaaagtttg caaattcaat agattacaga attcatgtag gcctgataag
     4141 cgaagcgcat caggcctttt tgcttctgtc atcggtttca ggctaaagga atctgccttt
     4201 ttccgaaatc attaatacag ttttttcgcg cagtccagcc agtcgccttt gaacggacgc
     4261 ttcatgtttt cgatagcgtc gatgatgtcg tggtgaacca gctgttcgtt ctggatacct
     4321 acgcaacgac caccgtaacc tgccagcagc agatcgatag cgtaagcgcc catacgggaa
     4381 gccagaatac ggtcgtaagg caccggagaa ccaccgcgct ggatgtggcc cagcacagtt
     4441 gcgcgggttt cacgaccggt ttctttctcg atgaaatgcg ccagttcgtc aacatcacac
     4501 atatgttcgg taatcgccac gatcgcgtgt tttttacctt tcgcgatacc cgctttgatt
     4561 tcgtttacca ggtcttcacg gctgaattca acttccggaa ccacaacgaa ttcacagcca
     4621 ccggcaatgg ccgcagccaa cgtcagatcg ccacaataac ggcccatcac ttccaccacg
     4681 gaaatacgct ggtgagaaga agaggtgtca cgcagacggt cgatcgcttc tacaacggtg
     4741 ctcagcgcag tgaagaaacc gatagtgtag tcagtgcctt tgatgtcgtt gtcgatagtg
     4801 cccggcaggc cgatgcacgg gaagcccatt tcggtcagac gcattgcacc catgtaggaa
     4861 ccgtcaccgc cgataaccac cagcgcgtcg atcccacgtt ttttcaggtt ttcgatagcc
     4921 acggcgcgga tgttctcgtc gcggaattcc gggaaacgcg cagaaccgag gaacgtaccg
     4981 ccacggttga tcatgtcaga aacgctgtaa cggtctagct gtaccatacg gtcttcatac
     5041 agacccagat agccgtcata aatgcccatt acttccagac cttctgtcag cgcagaacga
     5101 acaaccccgc gaattgcggc gttcatgcct ggcgcatcac cgccgcttgt caacacaccg
     5161 attttcttaa tcatgactac ctctgaactt tggaatgcaa aatgaaatct gttgccggaa
     5221 gtcttcttgc acatcgaagt gatccaacga atgtgcaaat agtataacaa tcacttcctg
     5281 ctgaattgat tcaggtcagg ccaaatggcg gtattttata cacaaaatgc gggtctggct
     5341 ctcttttata ctgattatga aagcatagac cgtttaccct ccctgggtac gacggaacag
     5401 gggtcctgat ggataatcac atccgatccc ggaaaacgcc gtaaaatagc ctgctctacc
     5461 tgatccgcca ccatatgtgc ctgaaccaaa ggcagagagt cttccatttc caaatgaatc
     5521 tgaataaagc gggtcggccc tgactgccgc gtgcgaagat cgtgagcgcc gctaacaccc
     5581 ggccaggaag tcacgatatc aataatttct tgccgttcct catcaggcaa tgcgcgatcc
     5641 agtaatgact gtaccgcctc atatcccatg cgtaacgcgc tatataaaat atagatgccg
     5701 atccccaatg caaacagagc atcggcgcga tgccagccgt accaggacaa ccccagcgcc
     5761 agcagaattg cgccgttcat cataacatca gactggtaat gtagcatatc agcccgcacc
     5821 gcctggcttt gcgtccggcg caccacccaa cgctgaaacg agacaaggat aatcgtacaa
     5881 attagcgcca caattgtcac gataaccccg acgcctggat ctgtcatcgg tgttggagat
     5941 accagatgtt gaatacccgt caaaaacagg aatagtgccg aaccggagat aaacatactt
     6001 tgcgccagcg ccgcgaggga ctcagcttta ccgtgaccaa acgagtgatt atcgtcggca
     6061 ggttgcaggg aatatcgcac caccagtaaa ttcgtcaacg acgcaccgat atccaccagc
     6121 gaatccacca gcgcggcgag aatactcacc gacccggtat accaccatgc aaaaatttta
     6181 atcagcaata gcagcgaagc catcgccgtc gcagcaatcg ccgcccgact gaccagccgt
     6241 ccataagatt gattcataaa tactcccgct atcaactgac ggtagtataa cggaagcaaa
     6301 tcatctgcaa tgcattaagc agcaggcaaa ttgaggataa aaaaaacccc cacatcatgt
     6361 gggggaagac agggatggtg tctatggcaa ggaaaacagg gtttactact gggaacgtga
     6421 gttgctacta ctcaatagct tcaacgatga acttttttgc cattgcgtca cgtcgcgcaa
     6481 ctgctccatt cgttgttgat gtttctcgtt taaaaccgct tgctgctccg gcgttaacag
     6541 gcgatacatt tggttgcgga cttttgccat ctcaacctga cgagcaattt gctcattcgc
     6601 cattttttct gcctgtgcgc gcacagcgtt ttcatcaaaa ttttctgcgg tgacaaggcg
     6661 atgcattgtc tccagttcgc taacattaac aggaggctgt tcgtgccggg cctgttgcat
     6721 aagatctcgc atctgctgac gctgatgttc ggttaaactt atgccgtcga acatatggct
     6781 ctgcgtactg cgctgcgtaa gttcttcacc cggatgccag ttatcgcctg aaccgacttc
     6841 agcagcgtgg cttaatgaac tgactgccag cgttgaggcc atgacggcag cggtaactat
     6901 gcgcatcatt tgctcccaaa atctttctgt cgcgattcaa cgatagagag tttacgattc
     6961 aggctgcaaa catgcgtcag ggggtgtaaa acaacgtaaa gtcatggatt agcgacgtct
     7021 gatgacgtaa tttctgcctc ggaggtattt aaacaatgaa taaaatcctg ttagttgatg
     7081 atgaccgaga gctgacttcc ctattaaagg agctgctcga gatggaaggc ttcaacgtga
     7141 ttgttgccca cgatggggaa caggcgcttg atcttctgga cgacagcatt gatttacttt
     7201 tgcttgatgt aatgatgccg aagaaaaatg gtatcgacac attaaaagca cttcgccaga
     7261 cacaccagac gcctgtcatt atgttgacgg cgcgcggcag tgaacttgat cgcgttctcg
     7321 gccttgagct gggcgcagat gactatctcc cgaaaccgtt taatgatcgt gagctggtgg
     7381 cacgtattcg cgcgatcctg cgccgttcgc actggagcga acaacagcaa aacaacgaca
     7441 acggttcacc gacactggaa gttgatgcct taagtctcaa tcctggtcgc caggaagcca
     7501 ccttcgacgg gcaaacgctg gagttaaccg gtacggagtt taccctgctc tatttgctgg
     7561 cacagcatct gggtcaggtg gtttcccgtg agcatttaag ccaggaagtg ctgggcaagc
     7621 gcctgacgcc tttcgaccgc gctatcgata tgcacatttc caacctgcgt cgtaaactgc
     7681 cggatcgtaa agatggtcac ccgtggttta aaaccttgcg tggtcgcggc tatctgatgg
     7741 tttctgcttc atgataggca gcttaaccgc gcgcatcttc gccatcttct ggctgacgct
     7801 ggcgctggtg ttgatgttgg ttttgatgtt acccaagctc gattcacgcc agatgaccga
     7861 gcttctggat agcgaacagc gtcagggtct gatgattgag cagcatgtcg aagcggagct
     7921 ggcgaacgat ccgcccaacg atttaatgtg gtggcggcgt ctgttccggg cgattgataa
     7981 gtgggcaccg ccaggacagc gtttgttact ggtgaccacc gaaggccgcg tgatcggcgc
     8041 tgaacgcagc gaaatgcaga tcattcgtaa ctttattggt caggccgata acgccgatca
     8101 tccgcagaag aaaaagtatg gccgcgtgga actggtcggt ccgttctccg tgcgtgatgg
     8161 cgaagataat taccaacttt atctgattcg tccggccagc agttctcaat ccgatttcat
     8221 aaacttactg tttgaccgcc cgctattact gctgattgtc accatgctgg tcagtacgcc
     8281 gctgctgttg tggttggcct ggagtctggc aaaaccggcg cgtaagctga aaaacgctgc
     8341 cgatgaagtt gcccagggaa acttacgcca gcacccggaa ctggaagcgg ggccacagga
     8401 attccttgcc gccggtgcca gttttaacca gatggtcacc gcgctggagc gcatgatgac
     8461 ctctcagcag cgtctacttt ctgatatctc tcacgaactg cgcaccccgc tgacgcgtct
     8521 gcaactgggt acggcgttac tgcgccgtcg tagcggtgaa agcaaggaac tggagcgtat
     8581 tgaaaccgaa gcgcaacgtc tggacagcat gatcaacgat ctgttggtga tgtcacgtaa
     8641 tcagcagaaa aatgcgctgg ttagcgagac catcaaagcc aaccagttgt ggagtgaagt
     8701 gctggataac gcggcgttcg aagccgagca aatgggcaag tcgttgacgg ttaacttccc
     8761 acctgggccg tggccgctgt acggcaaccc gaacgccctg gaaagtgcgc tggaaaacat
     8821 tgttcgtaat gctctgcgtt attcccatac gaagattgaa gtgggctttg cggtagataa
     8881 agacggtatc accattacgg tggacgacga tggtcctggc gttagcccgg aagatcgcga
     8941 acagattttc cgtccgttct atcggaccga tgaagcacgc gatcgtgaat ctggcggtac
     9001 aggtttgggg ctggcgattg ttgaaaccgc cattcagcag catcgtggct gggtgaaggc
     9061 agaagacagc ccgctgggcg gtttacggct ggtgatttgg ttgccgctgt ataagcggtc
     9121 ataacgtcaa ccttcaggta aaaaaatgcc tgatgcacta cgcttatcag gcctacaaaa
     9181 cctgttgaat ttatgggttt tgtaggctgg ataaggcgtt tacgccgcat ccggcatttg
     9241 agcaggatgc ctgatgcgac gctgatagcg tcttatcagg cctacactcc ggggttattt
     9301 tccccacaaa cggcgggaaa aatcttcgat cttgccgctc agtcggcgct tttgcatcgt
     9361 tcgcgtccag cttttcgata accctgcaac ggagagtaaa cggtgatact gatcgtcatc
     9421 aaacggcata tgccatgcga tggcggcagc ctcctgcacg gtcacatcgc tgacacggga
     9481 aaccaactcc agtggcgcat cagcagatac caaccctggt gcaattacgc tatacaacca
     9541 ccccacttta cccgtgtttt gcatcaactg cgctatatcg ctgatatcaa aatggtaatt
     9601 gagtttatag caaggtgagc gtggctggct gacctgaatt aatgcctctc cccagcggaa
     9661 aatatcacca atataaacat tactttccgt cagaccgtcg gttgagagat tttcgccaaa
     9721 cgcaggcgca acaaacagct ccgcctgttc cggaaattcc cgcgcccagt agagataatg
     9781 ctcacgagga taatgacaca gcgctctgtc tggcccgccg tggatctttt tctccgcctg
     9841 ttcgtcacct tccagcccca ggtccgtcag catcaactca ccatcaacct ggattttggc
     9901 aattgcgctg ggtttgcctt cgggataagc ctgaatcttg cctgtgtata catcaaccgg
     9961 atatcgcatc tgttccctct ccacgagaaa tttccccatt agaccatatt tattttatgt
    10021 caggcgtgct gttttcgcgg taagtatcca ggcagaaacg caattgaaaa ccggacgaac
    10081 gttagttcat ccggctgtgg ggattaagga agctggttta tttcaccgta cctaaaattt
    10141 cgattttcgc cgctctggct ttgactttac gtgaccagat agaggtaaga attggcacca
    10201 gaatcgaagt cacaatgacc gccgtcgcta ccagcgaagt tgctgccgga gccataggtt
    10261 taaacgcagg caccatttct gcaatcagca caggtgtcgc taccgcggcc ccagcggaac
    10321 tggaagcggc aattccggca gtgccatcgc caccgccaat caatttatcg gcgataatca
    10381 acggaatacc ggtcacgata attactgcca cacccaacag gatccccagc aaacctgtct
    10441 gggcaattac agtcaaatca atggtattgc ccagtgcgaa ggcaaagaat ggaatcagcg
    10501 tctgcaccgc tttgctgaaa aattctcgta actcagggtc aaggttcccc agggcaaagc
    10561 ccaccaggaa cggcaatact gcgccgacga aaacatgcgg ttcaaacgag gcaatcccgg
    10621 cagtgcccag aataatcatc gtcatgagcg gcccggactc caacgacatc aacacaaatg
    10681 ccccagcttc ttcttttgtg ccgtactgct gcatgatgga agcgtaaagt ccgccgttgg
    10741 tcatatccat cgccgccacc agcgccaacg ttgaaagtcc ggcaaaaaat ccaacttcaa
    10801 caccatgttc cggaataatg cgcgaggcaa ttgccgcaac cacccacgcg acggcaattt
    10861 tagttaccac cagcgtaccg gatttacgca gtaccgttcc cgtcgcgctt aattttattg
    10921 acgcccccat gcaaaaaaac cacaccgcca gaatgggcac cgtaccggta atcatcccgt
    10981 tggtgaatga tccaaaatat ttccccgccc ccggcgagaa ggtgtggcac agtgcgccaa
    11041 ggaatagcgg gacgagcatc atcccccccg ggattttctc aatcgagcgt tttatctgca
    11101 tttccatcac ctgtcggcat atttttaagg gctgatgcgt cattcctcaa cggagcatca
    11161 gtgttgatgg aaacgaagat aaacattcat ttgatcaata aaagtgatca aaaccacatc
    11221 aattgaaacg atgttttatt tttatcggat cgttgttttt attttgaaag tgatcacaaa
    11281 aaaaccaccg ccgttggcga tggttcattt tttaagctgc aatgcggcgt aaacgcctca
    11341 ttgcagcagg cgtcaaatga ttattttttc gccgcgaaac gtgccgctgc ttcgtcccag
    11401 ttcaccacgt tccagaactc tttaatgtag tccggacggc ggttctggaa tttcaggtag
    11461 taagcatgtt cccacacatc caggcccaca atcgggaagc cggaagcgcc agaaatggct
    11521 tcgcccatca gcggagagtc ctggttagca gtagaaacca ccgccagttt atcgcctttt
    11581 tgcaccagcc atgcccagcc ggaaccaaag cgggaagctg ccgctttttc aaattctgct
    11641 ttgaaattat caacggaacc gaaatcacgt tcgatagccg ctttcaggtc gccctgcagg
    11701 gtggtgcctt ttttcagacc tttccagaac agactgtggt tagcgtgacc gccagcgtta
    11761 ttgcgcagta cggttttctt gtctgctggc agctggtcca gtttggtgat cagctcttca
    11821 accggcaggt tagcgaattc tggcaggctt tccagcgccg cattggcgtt gttaacgtag
    11881 gcctgatggt gtttggtgtg gtggatttcc atggtctgct tatcgaagtg cggttccagg
    11941 gcatcgtaag catacggcag ggatggcagg gtataactca tattcatctc cagtgtggtc
    12001 gggcggccga ttgttaatgc cgcgtaagca gttggttcat tatagttaat taaatgatat
    12061 tgaaaatgat tatcaatgcc gtacttttca taagggtatg gttttgcagg aaaatgccca
    12121 agatgtgaag caaatcaccc acttaatgcc gtgattgcca gtaaatcggc agcggcggca
    12181 acaggcgaaa ggttaatcga cagctcaatt tttacactca tctcgtcgga gatgtgacgc
    12241 gacgaaaaat gatgaggata agaagatgag taacgcgatt acgatgggga tattttggca
    12301 tttgatcggc gcggccagtg cagcctgttt ttacgcgccg ttcaaaaaag taaaaaagtg
    12361 gtcatgggaa accatgtggt cagtcggtgg gattgtttcg tggattatcc tgccgtgggc
    12421 catcagcgcc ctgttactac cgaatttctg ggcgtattac agctcattta gtctctctac
    12481 gctgctgcct gtttttctgt tcggcgctat gtgggggatc ggtaatatca actacggcct
    12541 gaccatgcgt tatctcggca tgtcgatggg aattggcatc gccattggca ttacgttgat
    12601 tgtcggtacg ctgatgacgc caattatcaa cggcaatttc gatgtgctga ttaataccga
    12661 aggcggacgc atgacgttgc tcggcgttct ggtggcgctg attggcgtag ggattgtaac
    12721 tcgcgccggg cagttgaaag agcgcaagat gggcattaaa gccgaagagt tcaatctgaa
    12781 aaaagggctg gtgctggcgg tgatgtgcgg cattttctct gccgggatgt cctttgcgat
    12841 gaacgccgca aaaccgatgc atgaagccgc tgccgcgctg ggcgtcgatc ccctgtatgt
    12901 cgctttgcca agctatgttg tcatcatggg cggcggcgca atcatcaacc tcggcttctg
    12961 cttcattcgt ctggccaaag tgaaagattt gtcgctaaaa gccgacttct cgctggcaaa
    13021 accgctgatc attcacaatg tgttactctc agcactgggc gggttgatgt ggtatctgca
    13081 attctttttc tatgcctggg gccacgcccg cattccggcg cagtatgact acatcagctg
    13141 gatgctgcat atgagcttct atgtattgtg cggcggtatc gtcgggctgg tgctgaaaga
    13201 gtggaacaat gcaggacgcc gtccggtaac ggtgttgagc ctcggttgtg tggtgattat
    13261 tgtcgccgct aacatcgtcg gcatcggcat ggcgaattaa tctttctgcg aattgagatg
    13321 acgccactgg ctgggcgtca tcccggtttc ccgggtaaac accaccgaaa aatagttact
    13381 atcttcaaag ccacattcgg tcgaaatatc actgattaac aggcggctat gctggagaag
    13441 atattgcgca tgacacactc tgacctgccg cagatattga ttgatggtca ttccagtctg
    13501 ctggcgaaat tgctgacgca aaacacgctc actgcatgat gcctcatcac aaaatttatc
    13561 cagcgcaaag ggacttttca ggctagccgc cagccgggta atcagcttat ccagcaatgt
    13621 ttcgctggat gttggcggca acgaatcact ggtgtaacga tggcgattca gcaacatcac
    13681 caactgcccg aacagcaact cagccatttc gttagcaaac gacacatgct gactactttc
    13741 atgctcaagc tgaccgataa cctgccgcgc ctgcgccatc cccacgctac ctaagcgcca
    13801 gtgtggttgc cctgcgctgg cgctaaatcc cggaatcgcg ccctgccagt caagattcag
    13861 cttcagccgc tccgggcaat aaataatatt ctgcaaaacc agatcgttaa cggaagcgta
    13921 ggagtgttta tcgtcagcat gaatataaaa gagatcgcca cgggtaatgc gataagggcg
    13981 atcgttgagt acatgcagac cattaccgcg ccagacaatc accagctcac aaaaatcatg
    14041 tgtatgttcg gcaaagacat cttgcggata acggtcagcc acagcgactg cctgctggtc
    14101 gctggcaaaa aaatcatctt tgagaagttt taactgatgc gccaccgtgg ctacctcggc
    14161 cagagaacga agttgattat tcgcaatatg gcgtacaaat acgttgagaa gattcgcgtt
    14221 attgcagaaa accatcccgt ccctgacgaa tatcacgcgg tgaccagtta aactctcggc
    14281 gaaaaagcgt cgaaaagtgg ttactgtcgc tgaatccgca gcgataggcg atgtcagtaa
    14341 cgctggcctc gctgtggcgt agcagatgtc gggctttcat cagtcgcagg cggttcaggt
    14401 aacgctgagg cgtcagtccc gtttgctgct taagctgccg atgtagcgta cgcaatgaaa
    14461 gagaaaattg agccgccact gcatcccaat tcacctcatc ggcaaaatgg tcctccagcc
    14521 aggccagaag caagttgaga cgtgatgcgc tgttttccac gctctcctgc aaactgcttt
    14581 tacgcagtaa gagcagtaat tgcataaaca gaatttcacg actggcggtc gagggtaaat
    14641 catttccctc ttcttgttgt tccaactgtg caaccagttg gcgcacctgc tgtaatacgc
    14701 aatggttaac gcgccagtga gacggatact gcccatcctg ctcttgtggc agcaactgat
    14761 tcagcccggc gagaaactga aatcgatccg gcgagcgata cagcacattg gtcagacaca
    14821 gattatcggt atgttcatac agatgccgat catgatcgcg tacgaaacaa accgtcccac
    14881 cggtgatggt atagggctgc ccattaaata catgaatacc cgtgccatgt tcgacaatca
    14941 caatttcatg aaaatcatga tgatgttcag gaaaatccgc ctgcgggagc cggggttcta
    15001 tcgccacgga cgcgttacca gacggaaaaa aatccacact atgtaatacg gtcatactgg
    15061 cctcctgatg tcgtcaacac ggcgaaatag taatcacgag gtcaggttct taccttaaat
    15121 tttcgacgga aaaccacgta aaaaacgtcg atttttcaag atacagcgtg aattttcagg
    15181 aaatgcggtg agcatcacat caccacaatg aagcaaattg tgaacatcat cacgttcatc
    15241 tttccctggt tgccaatggc ccattttcct gtcagtaacg agaaggtcac gaattcaggc
    15301 gctttttaga ctggtcgtaa tgaaattcag caggatcaca ttatgacctt tcgcaattgt
    15361 gtcgccgtcg atctcggcgc atccagtggg cgcgtgatgc tggcgcgtta cgagcgtgaa
    15421 tgccgcagcc tgacgctgcg cgaaatccat cgttttaaca atggcctgca tagccagaac
    15481 ggttatgtca cctggaatgt ggatagcctg gaaagtgcca ttcgccttgg attaaacaag
    15541 gtgtgcgagg aagggattcg tatcgatagc attgggattg atacctgggg cgtggacttt
    15601 gtgctgctcg accagcacgg tcagcgcgtg ggtctgcccg ttgcttaccg cgatagccgc
    15661 accaatggcc taatggcgca ggcacaacag caactcggca aacgcgatat ttatcaacgt
    15721 agcggcatcc agtttttgcc cttcaatacg atctatcagc tacgtgcact gacagagcag
    15781 caaccagaac ttattccaca cattgctcac gctttgctga taccggatta ctttagttat
    15841 cgcctgaccg gcaagatgaa ctgggaatat accaacgcca cgaccacgca actggtcaat
    15901 atcaatagcg acgactggga cgagtcgcta ctggcgtgga gcggtgccaa caaagcctgg
    15961 tttggtcgcc cgacgcatcc gggtaatgtc ataggtcact ggatttgccc gcagggtaat
    16021 gagattccgg tggtcgccgt tgccagccat gataccgcca gcgcggttat cgcctcgccg
    16081 ttaaacggtt cacgcgccgc ttatctctct tctggcacct ggtcattgat gggcttcgaa
    16141 agccagacgc catttaccaa tgacacggcg ctggcagcca atatcaccaa cgaaggcggg
    16201 gcggaaggtc gctatcgggt gctgaaaaat attatgggct tatggctgct tcagcgagtg
    16261 cttcaggagc ggcaaatcaa cgatcttccg gcgcttatcg ccgcaacaca ggcacttccg
    16321 gcctgccgct tcatcatcaa tcccaatgac gatcgcttta ttaatcctga cgagatgtgc
    16381 agcgaaattc aggctgcgtg tcgggaaacg gcgcaaccga tcccggaaag tgatgctgaa
    16441 ctggcgcgct gtattttcga cagtctggcg ctgctgtatg ccgatgtgtt gcatgagctg
    16501 gcgcagctgc gtggtgaaga tttctcgcaa ctgcatattg tcggcggcgg ctgccagaac
    16561 acgctgctca accagctgtg tgccgatgcc tgcggtattc gggtgatcgc cgggcctgtt
    16621 gaagcctcga cgctcggcaa tatcggcatc cagttaatga cgctggatga actcaacaat
    16681 gtggatgatt tccgtcaggt cgtcagcact accgcgaatc tgaccacctt tacccctaat
    16741 cctgacagtg aaattgccca ctatgtggcg cagattcact ctacacgaca gacaaaggag
    16801 ctttgcgcat gaccactcaa ctggaacagg cctgggagct tgcgaaacag cgtttcgcgg
    16861 cagtagggat tgatgtcgag gaggcactgc gccaacttga tcgtttaccc gtttcaatgc
    16921 actgctggca gggcgatgat gtttccggtt ttgaaaaccc ggaaggttcg ctgaccggtg
    16981 gtattcaggc tactggtaat tatccgggca aagcgcgtaa tgccagcgag ctgcgtgccg
    17041 atctggaaca ggctatgcgg ctgattccgg ggccaaaacg gcttaatttg catgccattt
    17101 atctggagtc agacacgcca gtctcacgtg accaaatcaa accagagcac ttcaaaaact
    17161 gggttgaatg ggcgaaagcc aatcagctcg gtctggattt taacccctcc tgtttttcac
    17221 atccgctaag cgccgatggc tttacacttt cccatgccga cgaccgcatt cgccagttct
    17281 ggattgacca ctgtaaagcc agccgccgtg tttcagccta ttttggtgag caactcggca
    17341 caccgtcggt gatgaacatc tggatcccgg atggcatgaa agatatcacc gttgaccgtc
    17401 tcgccccgcg tcagcgtttg ctggcagcac tggatgaagt gatcagcgag aagctaaacc
    17461 ctgcgcacca tatcgacgcc gttgagagca aattgtttgg cattggcgcg gagagctaca
    17521 cggttggctc caatgagttt tacctggggt atgccaccag ccgccagacg gcgctgtgcc
    17581 tggacgccgg gcatttccac ccgactgaag tgatttccga caagatttcc gccgccatgc
    17641 tgtatgtgcc gcagttgctg ctgcacgtca gccgtccggt tcgctgggac agcgatcacg
    17701 tagtgctgct ggatgatgaa acccaggcga ttgccagtga gattgttcgt cacgatctgc
    17761 tcgaccgggt gcatatcggc ctcgacttct tcgatgcctc tatcaaccgc attgccgcgt
    17821 gggtcattgg tacacgcaat atgaaaaaag ccctgctgcg tgcgttgctg gaacctaccg
    17881 ctgagctacg caagctggaa gcggcgggcg attacactgc gcgtctggcg ctactggaag
    17941 agcagaaatc gttgccgtgg caggcggtat gggaaatgta ttgtcagcgt cacgatacgc
    18001 cagcgggtag cgaatggctg gagaacgtgc ggacttatga gaaaaaaatt ttgagtcgcc
    18061 gcgggtaaac actgccggat gcggcacaag tgccttatcc ggcctacggg tcggcaatag
    18121 ttgtaggcct gataagacgc gacagcgtcg catcaggcat tgattgccgg atgcggcacg
    18181 agtgccttat ccggcctacg ggtcagcaac agttgtaggc ctgataagac gcgacagcgt
    18241 cgcatcaggc attgattgcc ggatgtggcg cgagtgcctt atccggccta caggtcgtgc
    18301 atccgacaac accgaattaa caggaacaca gaacatgcaa aacataaccc agtcctggtt
    18361 tgtccaggga atgatcaaag ccaccaccga tgcctggctg aaaggctggg acgagcgcaa
    18421 cggcggcaac ctgacgctgc gcctggatga cgccgatatc gcaccatatc acgacaattt
    18481 tcaccaacaa ccgcgctata tcccgctcag ccagcccatg cctttactgg caaatacacc
    18541 gtttattgtc accggctccg gcaaattctt ccgtaacgtc cagcttgatc ctgcggctaa
    18601 cttaggcatc gtaaaagtcg acagcgacgg cgcgggctac cacattcttt gggggttaac
    18661 caacgaagcc gttcccactt ctgaacttcc ggctcacttt ctctcccact gcgagcgcat
    18721 taaagccacc aacggtaaag atcgggtgat catgcactgc cacgccacca acctgatcgc
    18781 cctcacctat gtacttgaaa acgacaccgc ggtcttcact cgccaactgt gggaaggcag
    18841 caccgagtgt ctggtggtat tcccggatgg cgttggcatt ctgccgtgga tggtgcccgg
    18901 cacggacgaa atcggccagg caactgcaca agagatgcaa aaacattcgc tggtgttgtg
    18961 gcccttccac ggtgtgttcg gcagcgggcc gacgctggat gaaaccttcg gtttaatcga
    19021 caccgcagaa aaatcagcac aagtattagt gaaggtttat tcgatgggcg gcatgaaaca
    19081 gaccatcagc cgtgaagagt tgatagcgct cggccagcgt ttcggcgtta caccactcgc
    19141 cagtgcgctg gcgctgtaag gagcaaacat gatccgcaaa gcctttgtca tgcaggtaaa
    19201 ccccgacgcc cacgaagagt atcagcgtcg gcataatccc atctggccgg aactggaagc
    19261 agtgctgaaa tctcacggtg cgcataacta cgccatctat ctcgacaaag cgcgtaatct
    19321 gctatttgcc acgatagaga ttgaatctga agagcggtgg aatgcggttg ccagtacaga
    19381 tgtttgccaa cgttggtgga aatatatgac cgacgttatg cccgctaatg cggataacag
    19441 cccagtcagt agcgaactgc aagaagtgtt ttacctgcct taatgagttg cggtgccgga
    19501 aaatatccag caccgccctt tcatcagaag aagtatttaa agcgaacgcg tgcgccgtaa
    19561 cggtcatcac tatcgtcgcc gtgtatctta tcgccgtcgc tatccagaat ggagtaatac
    19621 gtgccgaggt aaatattaaa gttctccata tccatcacat tagcgaactg ataagacgca
    19681 tgaatggtgt gaatgttgta tgttccttca tcatcaatcc agcaatcgtt atcacaaacc
    19741 acgccactaa attcatcaat cttattatgt gcgtagatat aacccagctc gaaacgtttc
    19801 cacagcgcgt taatcccagc ggtgaaatct ttctcattat tagcatctaa ataggcggta
    19861 ttaagattaa ccacgatgcc attttccgga tcggttttca ggccattcca ggtcatgctc
    19921 atgccataac cggtacgatc ggactgatcg acaaaattac ccttgctatc ggtataacca
    19981 taagcattat ttaccacgtt cgcttccatc gctgcggaaa cggtgaattc ttccgtcggc
    20041 gaccaggcaa ttaccggacg cagataagca acatttttct gctgttccat atcgcgtcca
    20101 tgataattac cgtcgttata taaagatgtt ccgtcttcca gtaacgtgtt taattcaaaa
    20161 taccagttat cgagttgttt gctgacgagg aaattaccgc cagcgttaga acgcccgcgg
    20221 ccctctttca tcatatagat ataaccgctg ccatcgtcat aaagatcgtt cgcagtatta
    20281 ccggaatgtt caacaaaggt atcctgattc agcgggaaca tatcgtaggc ttcaaaacgg
    20341 cctactttga ccttccagtc gttttctttg ccaaagaaga aaaccgcatc atcgatattt
    20401 actgaaccgt gcatatcccc cagcggttgt gcggagaacc cagcgaaata gccattatcc
    20461 agttttcgca taccatcaaa acctaacaga atacgaccat tgagattcca ctgttcatta
    20521 gtgggatcgc tattcacatc agcgttggtc attgccagca ggccatgatt actttccgca
    20581 tccatattaa attctacgtc accgtagatt tttaaatcgc cataccctga aagcaggaga
    20641 ttaggcgggg tggcgttttt cttctctgac tccgtcgttg attgaccgtt taccggcgtg
    20701 ttgccctgtg cggttttaat ttcgcggatc tcggcggctt gttgtgtctg aagctgttta
    20761 acctgcccct ctgcttttgc tgcccgcatt tctgccgctt ccaggcgttc ttccagcaat
    20821 gccatgcgtt gttccagcgt taaatgctgt gtttttgcca taccggtact acatgccaat
    20881 aataaaccga tggctaaaga taatgtcgat tttttcatta tttacgttcc ctgaaataaa
    20941 ggagacccta cgctttccaa aaggaatacg tatatagaga aatataaggt gtgcactttc
    21001 gaatttttaa tccaacttca gcaggccgat ggatagtatc ccgccatata atatgagtaa
    21061 atccgctgat ttcctggaac gtgaggaata taacaatagt gccgttttta actaaatatc
    21121 gtaaaaaata ttagatatga ttcacgctga ctcataagcc acaaatataa ataacgctta
    21181 aacaaattat ctgagatatt ttaacattca caaaatcatt aaataatgat actttattca
    21241 caaaatttat ccttcactct gctttatatt gttacgactt cgtgacatat ccgtgctcat
    21301 cacaaacccg ccccgcgatt acaattaact gaaatatttc atcgaccatt tcgttgtaat
    21361 cgcataacgc tcgtggaaat gagtcttcgg ccatccagct tgagtttgcg tcctgaagtt
    21421 gctctttatc ccagtcagag tacgggactt tatctctgat gcggcgaacg tattttttag
    21481 cctcgagttg atactggcct gccgaattaa taaacgagaa attcatgccg cttttatccg
    21541 cttctttggc ttgcgccacc agcgtttcca gttcagacac tttcttcatt gccgcttctg
    21601 catcaaactt atcttgcgat atcaggttat taatttgttt cgctgaaatc atgactgcca
    21661 gagagtagta gtggaatgtt ttccctttcg caaacgcatc gtctttataa ttttcctggg
    21721 tgtaatattt atccatttcg ttaatggtat tacccaacgc tacggcagca tcaatataac
    21781 tcaccgccac gccatcaata ggttgcagcg caggcattaa cgccactaca cgcgttttgt
    21841 ttataaaaaa ataac
//
LOCUS       DAFGPF010000083        21288 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFGPF010000083 DAFGPF010000000
VERSION     DAFGPF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.083"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            29..105
                     /locus_tag="LSX49_003461"
     tRNA            29..105
                     /locus_tag="LSX49_003461"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:63..65,aa:Arg,seq:acg)
     gene            386..952
                     /gene="yqaB"
                     /locus_tag="LSX49_003462"
     CDS             386..952
                     /gene="yqaB"
                     /locus_tag="LSX49_003462"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HBL7169826.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
                     QCVVFEDADFGIQAARAAGMDAVDVRLL"
     gene            949..1377
                     /locus_tag="LSX49_003463"
     CDS             949..1377
                     /locus_tag="LSX49_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBL7169827.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGVSHPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            1450..3006
                     /gene="gshA"
                     /locus_tag="LSX49_003464"
     CDS             1450..3006
                     /gene="gshA"
                     /locus_tag="LSX49_003464"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HBL7169828.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTE
                     PFAVWLEKHA"
     gene            3156..3671
                     /gene="luxS"
                     /locus_tag="LSX49_003465"
     CDS             3156..3671
                     /gene="luxS"
                     /locus_tag="LSX49_003465"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBL7169829.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARNILERDVRINSNEELA
                     LPKEKLQELHI"
     gene            complement(3722..4834)
                     /locus_tag="LSX49_003466"
     CDS             complement(3722..4834)
                     /locus_tag="LSX49_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7169830.1"
                     /translation="MIWQLTDDKRWSALRQRFSWVEEMHHTPQDPEHHGEGDVGVHTE
                     MVLNALITLPEFQQLPAQQQEVLWAAALLHDVEKRSTTVQENGRIQSPGHARRGELTA
                     RQILWRDIPTPFVLREQIVALVRLHGLPLWLLERPEPERLLLTAAMRIDTRLLALLAR
                     ADLLGRQSPDQQSMLERIDLFELFCHEQQCWGKMRPFVSDSARWHYLTHEQSSPDFVP
                     WEAEPFEVILLCGLPGMGKDRYISEQCQGMDVISLDDMRRRINASPDDKTATGRIVQQ
                     AKEEARVFLRQKKPFIWNATNITRQLRSQLISLFTAYGARVKIVYLEVPWAQWNQQNA
                     RREYAVPEAVVMRMASRLEVPQPDEAHSVEYRMTDR"
     gene            complement(4831..5538)
                     /locus_tag="LSX49_003467"
     CDS             complement(4831..5538)
                     /locus_tag="LSX49_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase family protein"
                     /protein_id="HBL7169831.1"
                     /translation="MNTQRKYGRTWHYPFSPGTTSDDRINTDYWQDLQTITQLVHTEK
                     LDGENNCLNRYGVFARSHATPTQSAWTYKIRQRWQLLKNDLGNLELFGENLYAVHSIE
                     YRALEQDFYLFAVRCQDMWLSWEEVQFYAALFDFPCVPEISGPQPGNDEKSWQRDFLA
                     LTNARGTFDPWDTQTCQPCTLEGIVSRNHDAFSVADFSHNVFKYVRKNHVKTTVHWKR
                     HWQRARMAHEFVYGEQS"
     gene            complement(5796..7334)
                     /gene="emrB"
                     /locus_tag="LSX49_003468"
     CDS             complement(5796..7334)
                     /gene="emrB"
                     /locus_tag="LSX49_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HBL7169832.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESLHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(7351..8523)
                     /gene="emrA"
                     /locus_tag="LSX49_003469"
     CDS             complement(7351..8523)
                     /gene="emrA"
                     /locus_tag="LSX49_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HBL7169833.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            complement(8650..9180)
                     /gene="emrR"
                     /locus_tag="LSX49_003470"
     CDS             complement(8650..9180)
                     /gene="emrR"
                     /locus_tag="LSX49_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HBL7169834.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQGGVVLEAMS"
     gene            complement(9271..9606)
                     /gene="ygaH"
                     /locus_tag="LSX49_003471"
     CDS             complement(9271..9606)
                     /gene="ygaH"
                     /locus_tag="LSX49_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HBL7169835.1"
                     /translation="MSYEVLLLGLLVGAANYCFRYLPLRLRVGNARPTKRGAVGILLD
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            complement(9596..10333)
                     /gene="ygaZ"
                     /locus_tag="LSX49_003472"
     CDS             complement(9596..10333)
                     /gene="ygaZ"
                     /locus_tag="LSX49_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine exporter subunit YgaZ"
                     /protein_id="HBL7169836.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWVAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            complement(10457..11641)
                     /locus_tag="LSX49_003473"
     CDS             complement(10457..11641)
                     /locus_tag="LSX49_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169837.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMM
                     ILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISDKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGSWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            complement(11833..12825)
                     /gene="proX"
                     /locus_tag="LSX49_003474"
     CDS             complement(11833..12825)
                     /gene="proX"
                     /locus_tag="LSX49_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HBL7169838.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYGLTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNANTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEDDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            complement(12882..13946)
                     /gene="proW"
                     /locus_tag="LSX49_003475"
     CDS             complement(12882..13946)
                     /gene="proW"
                     /locus_tag="LSX49_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HBL7169839.1"
                     /translation="MADQNNPWDTTPAADSAAQSADAWGTPAAAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPSQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            complement(13939..15141)
                     /gene="proV"
                     /locus_tag="LSX49_003476"
     CDS             complement(13939..15141)
                     /gene="proV"
                     /locus_tag="LSX49_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HBL7169840.1"
                     /translation="MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGV
                     KDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDVELRE
                     VRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS
                     YPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTI
                     VFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSA
                     KDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKAALT
                     QQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRAL
                     DREGVNNG"
     gene            complement(15497..16456)
                     /gene="nrdF"
                     /locus_tag="LSX49_003477"
     CDS             complement(15497..16456)
                     /gene="nrdF"
                     /locus_tag="LSX49_003477"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBL7169841.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPDALTPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNLEKISQARREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
     gene            complement(16466..18610)
                     /gene="nrdE"
                     /locus_tag="LSX49_003478"
     CDS             complement(16466..18610)
                     /gene="nrdE"
                     /locus_tag="LSX49_003478"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBL7169842.1"
                     /translation="MATTTAERLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAF
                     MTTHVRPNSVAFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHASGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLATQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADVAISERYDEL
                     VADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHALRT
                     SMLLARERGETFAGFKQSRYASGEYFSQYLQSNWQPKTAKVGELFARSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL"
     gene            complement(18583..18993)
                     /gene="nrdI"
                     /locus_tag="LSX49_003479"
     CDS             complement(18583..18993)
                     /gene="nrdI"
                     /locus_tag="LSX49_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL7169843.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDESYIL
                     IVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA"
     gene            complement(18990..19235)
                     /gene="nrdH"
                     /locus_tag="LSX49_003480"
     CDS             complement(18990..19235)
                     /gene="nrdH"
                     /locus_tag="LSX49_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBL7169844.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            complement(19482..19811)
                     /locus_tag="LSX49_003481"
     CDS             complement(19482..19811)
                     /locus_tag="LSX49_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HBL7169845.1"
                     /translation="MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAE
                     AARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGA
                     LLSMRKS"
     gene            19963..20307
                     /locus_tag="LSX49_003482"
     CDS             19963..20307
                     /locus_tag="LSX49_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HBL7169846.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGEAS"
     gene            complement(20344..20793)
                     /gene="alaE"
                     /locus_tag="LSX49_003483"
     CDS             complement(20344..20793)
                     /gene="alaE"
                     /locus_tag="LSX49_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HBL7169847.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADILAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
BASE COUNT         5284 a         5379 c         5541 g         5084 t
ORIGIN      
        1 tatcagcagt aaaataaatt ttcccgatgc atccgtagct cagctggata gagtactcgg
       61 ctacgaaccg agcggtcgga ggttcgaatc ctcccggatg caccatattc tccgtaacct
      121 tcagcaatga aggtatcgaa gaggtagcgg tattaaccgc aggcaccagg gaggataacg
      181 ttgcgccagc agcggcccga agggcgaacg ccagtgagtc atcctcccgg atgcaccata
      241 ttatccaaaa aatttccttc aaaaatatct catttctaaa taactacttt atccatttcc
      301 tgaattttct tctccttctc catcagcgac aaaatcaagc aattacgcta aagtagcgtc
      361 atatttttcg acttgcgaga agaccatgta cgagcgttat gcaggtttaa tttttgatat
      421 ggatggcacc atcctggata ccgagcctac gcaccgtaaa gcgtggcgcg aagtattagg
      481 gcactacggt cttcagtacg atgttcaggc gatgattgcg cttaatggct cgcccacctg
      541 gcgtattgct caggcgatta ttgagctgaa tcaggccgat ctcgacccgc atgcgttagc
      601 gcgtgaaaaa acagaagcag taagaagtat gctgctggat agtgtcgagc cgcttcctct
      661 tgttgaagtg gtgaaaagct ggcatggtcg tcgcccaatg gctgtaggaa cggggagtga
      721 aagcgccatc gctgaggcat tgctggcgca cctgggatta cgccgttatt ttgacgccgt
      781 cgtcgctgcc gatcacgtca aacaccataa acccgcgcca gacacatttt tgttgtgcgc
      841 gcagcgtatg ggcgtgcaac cgacgcagtg tgtggtcttt gaagatgccg atttcggtat
      901 tcaggcggcc cgtgcagcag gcatggacgc cgtggatgtt cgcttgctgt gagtgaagcg
      961 ttatcgcttt tctcgttgtt tgccagtagt tttctcagcg ctacactatt acccggcaac
     1021 tccgaagtcg tgctggtggc aatgttgctt tccggagtga gtcatccctg ggttttagtt
     1081 ttaacagcaa caatgggtaa tagccttgga gggttaacta acgttatcct tgggcgtttc
     1141 tttccattgc gtaaaacatc gcgctggcaa gagaaagcta ccggctggct gaaacgctat
     1201 ggtgcagtca cgctattatt aagctggatg cccgtggttg gcgatttact gtgtctgtta
     1261 gcgggatgga tgcgcatctc gtggggaccg gtaatctttt ttttgtgcct tggtaaagcg
     1321 ttacgctatg ttgcagttgc agcagctacc gttcagggca tgatgtggtg gcactaattg
     1381 taggcctgca catatggtca ccattacagt tatgctaatt aaaacgattt tgacaggcgg
     1441 gaggtcaatt tgatcccgga cgtatcacag gcgctggcct ggctggaaaa acatcctcag
     1501 gcgttaaagg ggatacagcg tgggctggag cgcgaaactt tgcgtgttaa tgctgatggc
     1561 acactggcaa caacaggtca tcctgaagca ttaggttctg cactgaccca taaatggatt
     1621 actaccgatt ttgcggaagc attgctggaa tttattacac cagtggatgg tgatattgaa
     1681 catatgctga cctttatgcg cgatctgcat cgctatacgg cgcgcaatat gggcgatgag
     1741 cggatgtggc cgttaagtat gccatgctac atcgcagaag gtcaggacat cgaactggca
     1801 cagtacggca cttctaacac cggtcgcttt aaaacgctgt accgtgaagg gctgaaaaat
     1861 cgctacggcg cgctgatgca aaccatttcc ggcgtgcact ataatttctc tttgccaatg
     1921 gcattctggc aggcgaagtg cggtgatatc tcgggcgctg atgccaaaga gaaaatttct
     1981 gcgggttatt tccgcgttat ccgtaactac tatcgcttcg gttgggtcat tccttatctg
     2041 tttggtgcgt ctccagcgat ttgttcttct ttcttgcaag gaaaaccaac gtcgctgccg
     2101 tttgagaaaa ccgagtgcgg tatgtattac ctgccgtatg cgacctctct tcgtttgagc
     2161 gatctcggct ataccaataa atcgcaaagc aatcttggta tcaccttcaa tgatctctac
     2221 gagtacgtgg cgggccttaa acaggcaatc aaaacgccat cggaagagta cgcgaagatt
     2281 ggtattgaga aagacggtaa gcggctgcaa atcaacagca atgtgctgca gattgaaaac
     2341 gaactgtacg cgccgattcg tccaaaacgc gttacccgca gtggtgagtc gccttctgat
     2401 gcgctgttac gtggcggcat tgaatatatt gaagtccgct cgctggacat caacccgttc
     2461 tcgccgattg gtgtagatga acaacaggtg cgattcctcg acctgtttat ggtctggtgt
     2521 gcgctggctg acgcaccgga aatgagcagt agcgaacttg cctgtacacg cgttaactgg
     2581 aaccgggtga tcctcgaagg tcgcaaaccg ggcctgacgc tgggtatcgg ctgcgaaacc
     2641 gcgcagttcc cgttaccgca ggtgggtaaa gatctgttcc gcgatctgaa acgcgtcgcg
     2701 caaacgctgg atagcattaa cggcggcgaa gcgtatcaga aagtgtgtga tgaactggtc
     2761 gcctgcttcg ataatcccga tctgactttc tctgcccgta tcttaaggtc tatgattgat
     2821 actggtattg gcggaacagg caaagcgttt gctgaagcgt accgtaatct gctgcgtgaa
     2881 gagccgctgg aaattctgcg cgaagaggat tttgtcgccg agcgcgaggc gtctgaacgc
     2941 cgtcagcagg aaatggaagc cgctgatacc gaaccgtttg cggtgtggct ggaaaagcac
     3001 gcctgacaga aaagaaaaag gccactcgtg agtggccaaa atttcatctc tgaattcagg
     3061 gatgatgata acaaatgcgc gtctttcata tactcagact cgcctgggaa caaagagttc
     3121 agaaaatttt aaaaaaaatt accggaggtg gctaaatgcc gttgttagat agcttcacag
     3181 tcgatcatac ccggatggaa gcgcctgcag ttcgggtggc gaaaacaatg aacaccccgc
     3241 atggcgacgc aatcaccgtg ttcgatctgc gcttctgcgt gccgaacaaa gaagtgatgc
     3301 cagaaagagg gatccatacc ctggagcacc tgtttgctgg ttttatgcgt aaccatctta
     3361 acggtaatgg cgtagagatt atcgatatct cgccaatggg ctgccgcacc ggtttttata
     3421 tgagtctgat tggtacgcca gatgagcagc gtgtcgctga tgcctggaaa gcggcaatgg
     3481 aagacgtgct gaaagtgcag gatcagaatc agatcccgga actgaacgtc taccagtgtg
     3541 gcacttacca gatgcactcg ttgcaggaag cgcaggatat tgcgcgtaac attctggaac
     3601 gtgacgtgcg catcaacagc aacgaagaac tggcgctgcc gaaagagaag ttgcaggaac
     3661 tgcacattta gtcagtttaa gcagaagagg ccgggctggt gaaaacaccg cccggctttt
     3721 gttacctgtc agtcatccga tattccacgc tatgtgcttc atcaggttga ggaacttcca
     3781 gccttgaggc catccgcatc acgaccgctt caggaactgc atactcgcgt ctggcatttt
     3841 gctggttcca ttgcgcccat ggcacttcca gataaacgat ttttactcgt gcgccgtaag
     3901 ccgtaaacag actgatgagc tggctgcgca gctggcgggt aatgttcgtt gcattccaga
     3961 tgaacggctt tttctggcgt aaaaaaacgc gcgcctcttc ttttgcctgt tgcacaatac
     4021 gtccggtggc ggttttgtcg tccggactgg cattgattcg ccgccgcata tcatcaaggc
     4081 tgataacgtc cattccctgg cactgttcac tgatatagcg atctttgccc atacccggta
     4141 agccacacag caaaataacc tcaaaaggtt cagcctccca gggaacaaaa tcaggagaac
     4201 tttgctcatg agtcaggtag tgccagcgtg cggaatcaga aacgaacggg cgcatttttc
     4261 cccagcattg ttgctcatgg caaaacagct cgaacagatc gatgcgttcc agcattgatt
     4321 gctgatccgg gctttggcga ccaagcagat cggcacgagc aagcaaagcg agcagacgcg
     4381 tgtcgatgcg cattgcagcc gtgagcaaca aacgctccgg ttccggacgt tccagtaacc
     4441 atagcggtaa cccatgcaga cgcaccagtg caacaatttg ctcgcgcagc acgaacggcg
     4501 ttgggatatc gcgccataaa atttgtcgag ccgtcagttc gccccgacga gcatgaccag
     4561 gagactgaat acgtccgttt tcctgcacgg tagtgctgcg cttttcaaca tcatgcaata
     4621 acgccgccgc ccataaaact tcctgctgtt gagcggggag ttgctggaat tctggcagag
     4681 taatgagggc gttaagcacc atttcggtat gtacgccgac gtcgccttca ccatgatgct
     4741 cagggtcttg tggcgtgtga tgcatctcct caacccagct aaaacgctga cgtagcgccg
     4801 accagcgttt atcgtcggta agttgccaaa tcatgactgt tctccataaa cgaactcatg
     4861 ggccatccgc gcccgttgcc agtggcgttt ccagtgcaca gtggttttga catgattttt
     4921 gcgcacatac ttgaagacgt tatgcgaaaa gtcagcgaca gaaaacgcat catgatttcg
     4981 gctgacaatg ccttccagcg tacagggttg acaggtttgc gtatcccagg gatcgaatgt
     5041 gccgcgcgca ttggtcagcg ccagaaaatc acgttgccag cttttttcat cattccccgg
     5101 ctgcgggccg gagatttcgg gaacgcaggg gaaatcaaac agagcggcgt aaaactgcac
     5161 ctcttcccag ctcagccaca tatcctggca gcgaacggca aacaggtaaa agtcctgttc
     5221 cagcgcgcgg tattcaatgg aatgaacggc gtagagattt tcaccaaaca actccaggtt
     5281 gccgagatcg tttttcagca gttgccagcg ttggcgaatt ttataggtcc atgccgactg
     5341 cgtaggcgtg gcatgggagc gggcaaacac gccgtagcgg ttaaggcagt tattttcgcc
     5401 atcgagtttt tctgtgtgca ccaattgcgt gatggtctgt aaatcctgcc agtaatcggt
     5461 gttaatgcgg tcatcgctgg tggtgcctgg agagaagggg taatgccagg ttctcccgta
     5521 tttacgttgg gtattcataa taatccatta ttttgtgtgt aataaatgta cgcccgcgag
     5581 ggtgcgagtt ttggggttaa aagaaaaatg tgagtatcac ccgcgaaagc gagggcgaag
     5641 gaaaaagaga attaacaacc tgagcgaatg ctcagaaccg gctaatggtg aatggaagag
     5701 tttggggcgg cgaaaagata caccgaatga gtgtataaaa caaccgtttg cagaatgagc
     5761 aaataaaaag ggagccgcag ctccctttgg caaccttagt gcgcaccgcc tccgccgcca
     5821 cctgcgccaa atggcggttt agcaaaccac accagcccca gcaggacgag gaatatcccg
     5881 gctgacatcc agaagatctc attggcggaa ataatcagcc cctgattggt tatctgctgg
     5941 gcaatccagc ctgatgcctg ctgttgcgtc ataccaagcc cttccagttg actgtacatc
     6001 gcctgagcat tcgggttgaa cgggtttacc gactcagtca actgtgcatg gtgcagcgac
     6061 tcgcggttgg tccacatggt cgtggttatc gacgtgccga tagaccccgc cagcgttcgc
     6121 gtaaagttgg agaggctcga tgccgccgcc agtcgttccg gtggcaaacc ggacagcgta
     6181 atggtggtca gcggcataaa gaagcaggcc accgcaaaac cctggataaa ctgtggccag
     6241 gccgacgcgc caaaatccat acccggttca aaggtatagg cacgccagta gaagcagacg
     6301 gcatacataa taaagctgaa ggttaccagt cggcgcatat ccagtttatg cgcgaagcgg
     6361 ccgataatcg gcgacaggat caccggaata atccctaccg gcgcagaggc cagccctgcc
     6421 cacgtcgccg tgtaaccgta gacctcctgc aacaactgcg gcagcagaac aatcgcgccg
     6481 aagtagagca tatacgcgag gctgatacac aagcagccga tggtgaagtt gcgcgactta
     6541 aacaacgaca gatcgactat cgggttatcg tcggtcagct cccagacaat caggaagcag
     6601 atagccacca ccgccaccac ggtgaggatg ataatttcct gtgatgagaa ccagtccagc
     6661 tctttaccgc ggtcgagcat aatctgcagg ctgccgatac caataaccag cagtgccagc
     6721 cccacggcat caatccgccg ccgttcggtg cgggtttcac gtccgcgcag agtttgcagt
     6781 gtcatcaaca ccaccgccac gccaatcggc acgttgatga agaatatcca gccccagtgg
     6841 taattatcac tgatataacc gccgaggatc gggccgcaaa ttggcgcaac aatcaccgtc
     6901 atcgaccaca acgccagcgc gatcgagcgt ttggctggcg ggtagttatt cagcaataga
     6961 ctttgcgaaa gcggaattaa cggcccggcg acaatcccct gaatcacgcg gaagaagatc
     7021 agcatattca ggctgctgga gacaccacac gcccacgacg caatagcaaa ggcgatggtg
     7081 gaccagagga acagtttcac ttccccgacg cgctttgcca gccagccggt aagcgggatc
     7141 gagatggcat tcgccacccc gaaagaagtg attacccacg ttccctggct gagcgatgag
     7201 cccagattcc cggcgatagt ggggatcgcc acgttagcaa tggtggagtc cagcacctgc
     7261 atgaatgtcg ccagtgacag cgcaatcgtc ataatgacca gttgtgcgcc ttccagcggt
     7321 ttttgctgtt gcatcacacg cacctctgga ttagccagcg ttagctttta cgatatcgtc
     7381 gatcagttta ttgacaggtg ccaggctgat ttcacgcgcg gtgcttaccg cgaccggtgt
     7441 ggaacgtact ttgtttgcca gtacctgacc gtcacggtta gtggtattga cactcaccag
     7501 cgtggataaa ccgatacgca gcgggtattg ctccagctgt ttctggtcca gttcaatacg
     7561 cacaggcaga cgctgaacga ctttgatcca gttaccggtg gcgttttgcg ccggaagcag
     7621 tgagaacgcg ctacctgtgc ccatatccag accaaccact ttaccggtgt atttcacatc
     7681 atcgccgtaa atatcggtgg tgatggtgac cggttgaccg atacgcatat tggcaatctg
     7741 cgtctcttta aagttggcat ccacccacat attggtggct ggaacgaccg ccatcagcgg
     7801 cgtcgttggg ctaatttgcg ccccaggctg taccgcgcgg cgggagacat aaccggtcat
     7861 cggactgaca atacgggtac gctccagcgc cagccaggcg ttacgtactt cggtggcagc
     7921 ctgttgtacg gcaggctgat cttccagttt cgtccccaga atcatcgcct gattggcatt
     7981 gtattgttga atagcgacgt ccagttgcgc ctgggcactg gtgacggcgt cgcgggcgtg
     8041 ttgcagctct tcgcgaccaa tcaggttggc attgcccagc ggcacacggc ggttgtagtc
     8101 gctttgtgct ttcgcgaggg cgattttttg cacctcaata ttcgcctgca actgtttgct
     8161 gttaatcatc agctggtggg tttggcgaac gctggaagcc agtgcagttt tggctttttc
     8221 aaacgcctgg cgagcatctg tcgggtcgag agtgaccagc acgtcgcctt cttttacaaa
     8281 atcggtgtta tcggcccaga ctttcgtcac gctgccagac acctgagaca taatttgaat
     8341 ctgattccct gccacgtatg cgtcatcggt ttcttcgaaa tgacgcagta ccaaaaacca
     8401 ataaatccct atcgctacgg caataattat aaagagcaag gtgagaagga ggagcagacg
     8461 cttacgtttg ccgctcttct ttaccggttg ctgcggggtt tgagtctccg catttgcgct
     8521 catattgttc tccacgatct tcttaactca tcggctgagc cgacctgctt gccaaaaagg
     8581 ccagcatgtt gcgatgctgg ccggttattt tttcttttat aaatctggat ttttgagcga
     8641 gatgacgcgt tagctcatcg cttcgagaac cacaccgccc tgttccatct ggtcgagacg
     8701 ggagagcaat ttgcgggtga tttgctcgag ctggtctttt tctgttgtgc tgagcgcgga
     8761 ccagagttga tgcaggcagt tatgctgcgg cggtaaaacc tcgcgcaaaa actcgtgacc
     8821 tttttccgtt aattgcagat gcaggcagcg gcgatcgtta tcgctttcac gacgttcgat
     8881 ccaaccgcgt ttttccagtt catcggcaat acgcgtcgcg ttggtacggg atgatccaag
     8941 agcacaactc aattcagaag gctgaatact gtggttttcc tgagactcca gcgtaatcaa
     9001 cgccataaac aacgtctcgt taatcccctg agccttcagc attttattgc ggttttccag
     9061 cagcttgctt tgcatatgca tgcaaagacg ggtcagaagg atctcctgat aaggaaaatc
     9121 ttcgtggcgg ctggcgcgaa attttagcat ttgttcaatg ggcgtaaacg aactatccat
     9181 ttgggtatga cctcattaat ttcagccgat atagtaacga cagtgacaaa taaagtaaat
     9241 gtattgtttt agaaaaatga ttcttgtgga ttatataatc gccatcactt tccaggcgag
     9301 cccataggcc agcgcactaa gcagtgttgg gatgataatg ctgcgtgttt tatagaaact
     9361 ggcacccagt accgcgaagc cgaccagtgt gggcacgaaa cggcgtgtat cgtgcatcac
     9421 ttctggtgcg gtagagacaa ccagcagagc gcatatcgag gcgatgccaa tggtgtcgag
     9481 caaaatacct accgcgccac gtttggttgg gcgggcatta cccacacgca ggcgcagcgg
     9541 cagatagcgg aagcaataat tcgccgcgcc aaccagtaac ccaagcagca gaacctcata
     9601 gctcatcggg cgctccttgc cagaatgcct ggattaacgc agtgaggcag ccacagacaa
     9661 tgcctgccag aatggcgacg ggaatagaaa atagcgttac gcctgcaagg gcaccaacta
     9721 acgctgcggt aacgcaaaga gattgtttgc gctggaaaga ggcgagcagg aaactcataa
     9781 agagtgccgg aagcataaaa cctaatgctg cttcaacggc gggataacct tgcagcaagc
     9841 cgctgccgga gaatgcccct attaccgtac caaataccca cgatgaccat gaactgaagg
     9901 caatgccgat catccagttt tcgctccagc ggcgattatt gcgtaccagt tttgcggttg
     9961 cggcggcaaa aacctcatcc gtcaggccaa acgcccacag ggcggttttc gatttttgca
    10021 gacgctgaat aatacggcta cgcagtgacg ggccatacaa aacatggcga acatccattg
    10081 ccatgacggt cagtgcagca acccacaaac tactcccggc tgccagcatc gcggtaatga
    10141 cgaactggct cgcgcctgca taaatgatgc aggagaaaaa aacgctttcg agaggagaga
    10201 atcccagacg ggtcgcattc agaccgaacg caaaggccac cggaatataa ctaataacaa
    10261 tcggtaaact gtctttgcat ccttccatga aggtcgccga accaggagca ggctgtggag
    10321 tagggctttc catagagtgt acgcttaacg attgttaata ttataaatag actgaatgaa
    10381 tatcttaacc ttatcagact gatgggcttc ttaacaccct tataagtgta aagccacgaa
    10441 aacggttgct gattgcttaa tttgcggctt cctgacgatg aaaacctcgc caccagacca
    10501 gtaagttaac cagggcaatc gtcgcgccag ccagacacac gccagcccaa ctgccatgtt
    10561 gccaggctga ggctgaaatt agcgaaccag cggcaccgcc aataaagtag ctggtcatgt
    10621 aacctgcggt caggcgatta cgcgcatcag ggtgtattcg ataaattacc gtctggttag
    10681 tgatatgcac gccctgcacg gtgaggtcca gcaccaggat gccgataatc agcgccagta
    10741 cggaagtgtg accaaaccag attgccagcc atgaaagtaa cagcagaagc agaccgaaag
    10801 ttgttgtgtg gtgcgatttg cccttgtcgg caaaaccgcc cgccggacga gcgcccaacg
    10861 ctccggcagc tcccgcaagt ccaaacagac caattacacc atcgctgtag ttaaaaggtg
    10921 gagcggcaag caaaaaggcc attgaggtcc agagaatgct gaagttggca aaggtcaggc
    10981 agcccagcaa cgcgcgggtg cgcaggatct tatcgctgat aaacatgctg aaaacggaac
    11041 caagcaactg tgggtagttg aggtgggttt ctgatttcat ttgtggcaga ccacgccata
    11101 atgccagcgc catcagtgcc attaacaccg aggcaaccca aaagacggtg cgccagccgc
    11161 cgaggtttgc cagcaatccg gcaacggtcc gtgcgagtaa gatccccaat agcaggccgc
    11221 tcataatggt gccaaccact ttgccgcgtt tgtccggtga ggccagcgtc gctgccagtg
    11281 gaaccagaat ttgtgccacg accgagaata aaccggttaa tgccgtaccg aggatcatca
    11341 tcgccagtga ctgactgctg gcagtgatta acataccgcc cgctgccagt aaggtcatcg
    11401 agacaatcag gcggcggcgt tcaaacatat caccgagggg aacaagaaac agcagacctg
    11461 cggcatagcc caactgcgcg gcggtaacaa taaagcccgc cgaactggcg gaaagggaaa
    11521 agttacgcgc gatggtgtcg agcaatggct gggcgtaata gttactggct accgccagac
    11581 cggtggcgat agacatcagc acgatcagcg ccgggctaag ctcatgatta ggtttagtca
    11641 ttatttttgt tcatcaggtg atgattaagc tggaaatcaa taatagcgga tgttgatgaa
    11701 tatgggatga aagatagatt gttgaaatgt gcggtgtggt ttgtaggtat gataagacgc
    11761 gccagcgtcg catcaggcat tgtgtacaga gcggcggatg aggcaaaaac gccttatccg
    11821 cccgaataaa aattacttct gcgctgccag cgcttcattc acccagccat cgaactgctg
    11881 ctggtgggct ttgatccaac catcaacgtg gccctgaata tcgtcttctg aggctttgcc
    11941 gtcatgcatg atggcgttct gggcgttaat atctgccact ggtaactgca taatggcaaa
    12001 cagtttcgct gctgccgggt ttttctcggc ccaggctttg ttggcaacga tatgcatggt
    12061 actgaccggg aagccgtaat tcgcgccatt cggcagtttg gtattggcat ttttatcgcc
    12121 cggcagtgcg gagaacggca cctgcaacca gaccacatct ttccccggtt tcagttcgtt
    12181 actcacccag tacggcgtcc aggtgtagta aaacaccggc ttaccctctt tgtaacgact
    12241 gatggtgtca gccatcatcg ctgcgtagtt cccctgatta tgcgtcacgg tattggtcag
    12301 tccatacgcg gcaagctggt ggttgatcgc accttcgcag ccccagcctg ggttacagcc
    12361 ggttaaatcc gctttaccgt cgccgttggt atcgaacagt ttggcgatct tcggatcttt
    12421 aagttgcgcg atgttggtaa ttttatactg gtcggcggtt ttcttatcga tcaggtaacc
    12481 ttgtgccgcg ccgttaacaa ataccccttc acgataaaat ttcttatcgc caccggcagc
    12541 ttcgtacatg ttgtcatgca gtggcgtcca gttcacggcg gtgaaggttg catcgccgga
    12601 agcaagcgag gtgtagccaa cgttgtaatc cacttcgctg ggtttattga cggtataacc
    12661 taatttctcc agcgcgcggc tgaccagcag cgtctggaag gtttcttcgg tgatggtgct
    12721 ttgaactgga ttaactgtaa tgcctttgcc cggcaggtcg gcagcaaaag tttgtgtaga
    12781 gataagcgtg gcaaacgctg tcgcaaaaag tacgctatgt cgcattgtta ttcctttttt
    12841 tggcagggtg atatgcccgg tgttaccggg caagtgcaga gttacttaat gaatgggcgg
    12901 gtcagcagac cgacagggcc agtggtgtac cagcgacggt tgccgcgact acgtgagtcg
    12961 cgcccaacgg cctgcgtcag gcgatcgagg ataatggcga ggatcacaat cccgacgccg
    13021 ccaacggtgg caagccccat atccagacga ccgataccgc gaagtaccat ctgacccagc
    13081 ccgccgacgg caatcatcga agcgatgacc accatagaaa gggccagcat cagcgtctgg
    13141 ttaacgcccg ccataatggt tggcatcgcc agcggtaact gaactttgaa cagcatctgg
    13201 ctcgggctgg caccgaatga gcgcgaggct tcaatcagat ccgccggaac ctggttaatt
    13261 cccagaatcg tcagacggat aatcggcggc agtgcaaaga tgatcgtcac caccacgccc
    13321 ggcacgttgc cgataccaaa cagcatgacg attggcacca gataaacaaa cgcgggcgtg
    13381 gtctgcatgg catcaagcag tggacgaata attttcgccg ctcgcggact tctcgccagc
    13441 cagatcccca acggcaaacc tatgacgata cagaacagca gggcggttaa caccagcgcc
    13501 agggtaacca ttgcctgtga ccaggcaccg attgcgccga tggcaatcag cgaaaccagc
    13561 gtcgccacgc ccattccgac cccggaaatc tgccaggcga tgagagcgaa aacgataatc
    13621 gccaccggcg cgggcatacc cagcagcaat tgctggaaac cgttgaggat gtaatcaacc
    13681 ggaacgcgca cgccctgaaa gacgggacga aaatgggtaa cgacccagtc gatcccttca
    13741 gtgacccaac tgtcgagcgg gatcagagtt ttatggaacg gatcgagaat attaaaatgc
    13801 tcgacgtttg gcgcaggcgt actggtcagc cagtcagcac caccgccgtc agtcggtgca
    13861 gcagccggtg taccccaggc gtctgcggat tgtgcagcac tgtccgccgc tggcgtggta
    13921 tcccacggat tattttgatc agccattatt taccccctca cgatctaaag cgcgcagcag
    13981 cattcctttc gaaatgatgc cgacatactg ttggtcctcg tcgaccacgg gcaccgcaca
    14041 gggtgcctgt ccgacatgag agagcaactc gctaagaggc gtttgtgcat cgaccgctaa
    14101 cggcgcatca atcagcgccg catcaagacc ttgctgctgc gttaacgcgg ctttaagcga
    14161 atcgatagac acagcgccga caaacttatt accgcgttcg atgacgtagc catattcgcg
    14221 atcttcatcc tgcaataatt tcagtgccga acgcgggccg aagccggggg ttttacgaat
    14281 taagccgttc ggtgtacgac gagcaatatc tttcgcactg aacacctggc taatatcgac
    14341 gccacggaag aaggtacgaa cataatcatt cgccggatta ttaagaattt catccggtgt
    14401 accaacctgc accacttcac cattttgcat aatggcaatt cggtcaccaa tacgcatagc
    14461 ttcatcgaga tcgtgggaaa taaagacaat ggtgcgctga tgtttcgcct gtaattttac
    14521 cagctcatcc tgcatctcgg tgcgaattaa tggatcgagt gccgagaagg cttcgtccat
    14581 taataatata tccggattaa tcgctaacgc gcgggctaat cccacacgtt gacgcatccc
    14641 gccagagagt tcatccgggt agctgtgggc ataattttcc agcccgacct gacgcagtgc
    14701 atcaagggct ttttcccggc gttcttcggc attaattccg gccagttcca taccgaacgc
    14761 agtattgtcc agcacggtca tatgcggcat taaggcaaag gactggaaga ccatcgcaat
    14821 cttttttctg cgcacctcac ggagttcgac gtcggatatt ttggcaatat ccacaccatc
    14881 aatcagcact tgcccgcggg tgggttcaat caggcgattg agaaggcgta ccattgtgga
    14941 tttacccgaa ccggataatc ccatgatgac aaatatctcg ccttcttcaa tggccagact
    15001 ggcgtctttt acgccaagcg atagcccagt tttttccaga atttgttctt ttgaaagtcc
    15061 ttgttcgata tatttgaaag ctcgctgtgg atgctcacca aatattttat aaagattttt
    15121 aatttctaat ttaattgcca tgcaatagaa agattcctgt tatttgttta tgtcgataca
    15181 ttacccaatg gaaatagtca cttttttcta ccctaacata ctgagaatct gaggcaaccc
    15241 ctgatggcaa atgtggcatg aatattgatg tgagcaaatc gccggaattt cccatgatat
    15301 aagggctgag agcaaatcga gaaaagttga tattttttgt caaagatagc aaaaaaacgc
    15361 ctgaatattg tggtttcagg cgaataatgc aacagagtat cagtgtagat caccacaaat
    15421 tatttgcgtg atataaagct atttggcggg aattatttcc ctgcagcggg tagtgatatt
    15481 tttgaaaata accccctcag aaattccagt cttcatcttc tgtttcgacc gcttttccca
    15541 tcacatatga agagcctgaa ccggaaaaga aatcgtgatt ttcatcggca ttcggcgaaa
    15601 gcgcggcgag gattgccgga ttcacttccg ccatttctgc gggaaatagc ggttcgtagc
    15661 ccagattcat caacgcctta ttggcgttgt aacagagaaa cgctttcaca tcgtcagccc
    15721 acggggtttc ggcgtacagc tcatcggtgt attgcaactc gttgtcatag agttccagca
    15781 acaaatcgaa ggcgaaactc ttcaattctt cacgtcgtgc ctgggagatc ttttccaggt
    15841 ttttctgata tttatagccg atgtagtaac cgtggactgc ttcatcccgg ataatcagac
    15901 ggatcaggtc tgcggtattg gttagctttc cgcggctgga aaaatacatc ggcagccaga
    15961 aaccggaata gaacaaaaaa gattcaagaa acacactggc gattttcttt ttcagcggat
    16021 catcaccgcg ataatgttgc tgaataatct gtgcttttcg ctgcaacggc gcgttttctt
    16081 cactccaggc gtaggcggca tcgacatctt tggtctggca cagcgtcgag aaaattgaac
    16141 tgtaagagcg ggcatgaacc gcttccataa agctgatatt tgataatacc gcctcttcat
    16201 ggggggtgag tgcatcgggc atcagcgagg gcgcgccgat aacattttgc agcgtgtcga
    16261 gcagcgtcag gccagtaaaa acgcgcattg ttagttgttg ttctacgaca cttaatgtct
    16321 gccatgcagg aatatcgttc gacagtggca ccttttctgg tagccagaaa ttgctggtca
    16381 ggcgattcca cacctccaga tctttatcgt cagatatctt gttccagttg atggcgctga
    16441 tacgtgagag tttcatagat attccttaaa gtgcacagga gacgcagcct tcaatttcag
    16501 tgccttccag cgccatctga cgcaggcgaa tgtaatagag cgttttgata cccttgcgcc
    16561 aggcgtaaat ctgcgctttg ttgatatcgc gagtggtggc ggtatcgggg aaaaacagcg
    16621 tcagcgacag cccctgatcg acatggcgag tcgcttccgc gtaggtgtcg atgatctttt
    16681 ctgcgccgat ttcgtaagcg tcctgataca gcgccagatt ttcgttagtc ataaacgggg
    16741 cagggtagta aacgcgcccg gttttgccct ctttgcgtat ctctactttc gccacaatcg
    16801 gatgaatact cgacgtggca tggttgatat aagagataga accggttggc ggcaccgcct
    16861 ggagattctg gttgtagata ccatagcgca tcacgtcgtc gcgcagctgc gcccacatct
    16921 cacgggtagg taacgtaata ccgctacggg caaacagttc gccaactttc gccgttttcg
    16981 gctgccagtt actttgcaga tattggctga aatattcacc actggcatag cgtgactgtt
    17041 tgaacccggc gaaggtttca ccgcgttcgc gcgccagcaa catcgaggta cgcagtgcgt
    17101 gccaagtgat ggtatagaaa tagagattgg tgaaatcgag tgcttccggc gaaccataag
    17161 cgatgccttc tcgcgccaga tagccgtgta aattcatctg ccccagtccg atggcgtgcg
    17221 aggcggcatt tccggcttcg atggacggca cgctgcggat atgactcata tctgacaccg
    17281 ccgttaaacc gcgtacggca gtctctaccg tgcgggcaaa gtcgggggaa tccatggtgt
    17341 gggcaatatt caacgaccct agattgcagg aaatatcatg gcctgtacgg gcatagtcga
    17401 gattctcgtc atattctgag gcgctgttaa cctgcaaaat ttctgagcag agattgctca
    17461 tatttatgcg cccggcgata gggttagcac ggttaaccgt gtcttcatac atgatgtacg
    17521 gatagccaga ctcaaactgg atctctgcca gtcgctggaa gaaatcacga gcgttgaggt
    17581 attttttgcg aatgcgttca tcggcaacca gttcgtcata gcgttcgctg atggcgacat
    17641 cggcaaacgg tttgccataa acccgctcaa cgtcataggg cgaaaacagc gccatctgcg
    17701 cattctcttt tgccagatgg aaagtgatat ccgggatcac cacgcccagc gacagtgttt
    17761 taatgcggat tttttcgtcg gcattttccc gttttgtatc gagaaaacgc agaatatcgg
    17821 gatgatgagc atgtaaatag actgccccag ccccctgacg cgcgccgagt tggttggcat
    17881 aggaaaatgc gtcttccagc attttcatca ccggaatcac gccagaagat tgattttcaa
    17941 tacgtttaat tggcgcgccc gcttcccgca gattcgacag caaaaatgct acgccgccgc
    18001 cgcgtttcga cagttgtagt gcggaattta ctgcccggcc aatcgactcc atattgtctt
    18061 caatacgcag cagaaaacag gaaaccagtt cgccgcgctg ctgcttaccg cagttgagga
    18121 atgttggcgt ggctggctga aagcgtcctg acagcatctc atcggtgagc tgcgtcgcca
    18181 gtgtttcatc gccttgtgcc agcgtcagcg ccaccatcgt gacgcgatcg gcaaaatctt
    18241 ccagataacg cttaccgtcg aatgtcttca acgtatagct ggtgtaaaac ttccatgctc
    18301 ctaggaatgt ctggaaacga aaaccgctgg cgtgcgcgtg ggcaaacagc gtaatgacaa
    18361 aatcgcgaga gtagcgatta aggacacttt catcatagta accttcgtta accagccagt
    18421 tcaggcgctg ctgctggcta ctgaaggcca cactgttcgg acgcacatgc gtcgtcataa
    18481 aggcgtctac tgcctggcga tctttatcga actgaatgcg acctgcgcta tcgtaaaggt
    18541 taagcatcgc attcagagcg tgataatcca tcgtttcctg cgtcaggcgt tctgcggttg
    18601 tcgttgccaa aattcagtta ctcctttacg aacgttttcg atatcgcttt gcgtacccat
    18661 gagttcaaag cggtacagcc acggcacgcc gcatttccgg gcaatcacat ctccggcgcg
    18721 gccatatgcc tcaccaaagt tgcgattacc cgaagcaata acgccgcgca gcaacgcccg
    18781 gttatgctcg tcgtttaaaa agcgaatgac ctgtcgtggc accgcgccag ccgtaccgcc
    18841 gccgccgtaa gagggcacga tcaggatgta agactcgtct acctgaatcc gttcccgctc
    18901 attgagcggg atgcgcaccg cgggcagccc taaacgttcg ataaaacgct gcgtattttc
    18961 ggagctgctg gaaaagtaga cgagctggct catgcactgg ccgcgtgtgg cgctggatgc
    19021 agacgattga tcatgtccgg gcggaaacca gaccagctaa gatcgcctgc aatcacaacc
    19081 ggcaactgac gaaagccctg agcacgcagc gcttctgccg cttcaggaac gcgatcgaca
    19141 ttaatcattt caaaatcaaa gccccggttt tccatcgccc gtttagtggc gtggcactga
    19201 acgcaatcgt tacgagtgta aatagtaatg cgcatgattc gtatttccgt ttaaaatgaa
    19261 gatacggcgc gatgatacgc gtcgggttgt ctctctgttg atacagagat actagatgta
    19321 gttgaaaaaa gattcaacca cacaatatat agcaaataat ggtcagggtt accctggggc
    19381 gagcgtgacg gggtaggggg atttttgtga ttcaccaggc aaaaagaaac cccgaagcca
    19441 ggcttcgggg tcaaagacgc gtatttatta tcatttttgc actacgattt gcgcatgctt
    19501 aacagtgcgc cgataaaaat acccaccgct gccgctgtac ccacactaca ccagggtctt
    19561 tcacgaacaa aagaatccgc gcagccaacg gcatcgcgcg cggcttgctg gacgcgagta
    19621 cgaccatgca ttcgcgccct ggtttctttc agtagagcct gcgctttact acgagcggct
    19681 tcggcttccc ctttggcgtc gctgccccag gacttcaata cagattcgag actgtcagct
    19741 aattgattga catcattctg gatatcctgc acgccatcat caacgtcgtt gcggttcggt
    19801 cggttaaaca tatgatcccc cattagaatt cgatgtaatt ttcagtgtag accataattt
    19861 tcttaactga ggttcatcgc ggctttatgg acttttctga aagcgttgtg aatgcgcaat
    19921 caggtaaggt aggcccgcgg ttgataataa cgaggatcaa atatgtattt acgaccagac
    19981 gaggtggcgc gcgtacttga aaaagtcggt tttactgtcg atgtggtaac ccagaaagcg
    20041 tatggttacc gccgtgggga aaattatgtc tatgttaatc gcgaagcgcg aatgggacgt
    20101 accgccctgg tgattcatcc aacattaaaa gaacgtagtt caacactggc tgaacccgct
    20161 tccgatatta aaacttgcga tcattaccag caatttccgc tctatttagc gggtgaacgt
    20221 catgagcatt acggtatccc gcatggcttt agttcgcgtg ttgcgcttga acgttatttg
    20281 aatggtttat ttggcgaagc cagttaaaga cgcgactggc gatgccagtc gcgaaaagaa
    20341 gggtcaggct tttacctgct ggtaacggct gactttaaac agtcggcggc aataatcgag
    20401 gaagtagcca taaaccgccc ccatcaacat cgaaacaacg atgtttgaac tgactgccgc
    20461 cataatctga tgccagtctg cgcccaccac taacaagatc gccacataca ccggtgactg
    20521 gaacgtcaca taagccagga tatccgccag attttttatc cagcctgacg ggctaacttt
    20581 gcgtgccgcg cgcataaaca gatcgcggta cataccgtat ggccatgcaa ttaagatgtt
    20641 caccggaatc gctaccaatc tggaataaaa agactgttcg aagctcattc cggagaggaa
    20701 aacttcaata cacatgttca cgacagaaca gtaaacaacc atcgcgaacg tatctgcaac
    20761 tgcatgacgc aagcgtgact gcggtgagaa catgctaatg ctccttaata aaagcgtaat
    20821 gggatgttaa tggagatgaa agcagtggat ctcattgcca tctgcatttt tgcatagcgt
    20881 atatcgctgg ctatgactaa tcaattagtg aaaaattttc atttaatctg tttttgtaga
    20941 taaaatattc cgtaacggcg cgttttttgt acattgtgga tttttacatg ccgatatgat
    21001 ttatttttaa ttaaatcaat tggatatgtg cttgccttta ttttcactca tgaaggtttg
    21061 ggggtgaggt aacgctataa gcgtagagaa ttcggtgtat gtagtgaccg ggtcattttc
    21121 agcatttttt atgacagata atgtacattg acagcagaaa gcaccagtga tagatgtttt
    21181 cttttattcg gttgaattgc atttttattc actttggttt tgtcaggctt gcggaattag
    21241 cgagcagaga gagccgctct gttcaccaat aaccgaaatt actcatca
//
LOCUS       DAFGPF010000084        20938 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFGPF010000084 DAFGPF010000000
VERSION     DAFGPF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20938
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.084"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            130..987
                     /gene="focA"
                     /locus_tag="LSX49_003484"
     CDS             130..987
                     /gene="focA"
                     /locus_tag="LSX49_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HBL7169848.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLIGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
     gene            1042..3324
                     /gene="pflB"
                     /locus_tag="LSX49_003485"
     CDS             1042..3324
                     /gene="pflB"
                     /locus_tag="LSX49_003485"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL7169849.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            3516..4256
                     /gene="pflA"
                     /locus_tag="LSX49_003486"
     CDS             3516..4256
                     /gene="pflA"
                     /locus_tag="LSX49_003486"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HBL7169850.1"
                     /translation="MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWD
                     THGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHT
                     CLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
                     NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYK
                     LDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(4353..5501)
                     /locus_tag="LSX49_003487"
     CDS             complement(4353..5501)
                     /locus_tag="LSX49_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169851.1"
                     /translation="MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGIGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQTENHDSTSITSMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            5815..6441
                     /locus_tag="LSX49_003488"
     CDS             5815..6441
                     /locus_tag="LSX49_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL7169852.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDAPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRMSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            complement(6477..7340)
                     /gene="dmsC"
                     /locus_tag="LSX49_003489"
     CDS             complement(6477..7340)
                     /gene="dmsC"
                     /locus_tag="LSX49_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     DmsC"
                     /protein_id="HBL7169853.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMLGLWVLMGIGFISSMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLVVTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVMSVMQGAELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCVWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAN"
     gene            complement(7342..7959)
                     /gene="dmsB"
                     /locus_tag="LSX49_003490"
     CDS             complement(7342..7959)
                     /gene="dmsB"
                     /locus_tag="LSX49_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HBL7169854.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            complement(7970..10414)
                     /gene="dmsA"
                     /locus_tag="LSX49_003491"
     CDS             complement(7970..10414)
                     /gene="dmsA"
                     /locus_tag="LSX49_003491"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HBL7169855.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGINNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDTKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            complement(10714..11706)
                     /locus_tag="LSX49_003492"
     CDS             complement(10714..11706)
                     /locus_tag="LSX49_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL7169856.1"
                     /translation="MSIKQLKDGRYQVDVRPQGAEGKRIRKIFALKSKAQEFEKYVLQ
                     NFHDKPWQAKPADQRRLSELLDAWWMLDGRNQAYGDSYRVRLGKVVREMGDPRASQMT
                     RKFMLEYRSEKLQAGLMPSSINRDLCVLSTMFTVLIEAEVFHNANPVRGIRKLKVQNT
                     EMAFLSDDEIERLLERLEGDVRRVAILCLSTGARWSEASELRGEHIVGNRVTFFNTKN
                     GKSRSVPVADSVVPLIKTRRTGLLYQVDYLKFREILQEVKPDLPKGQATHVMRHTFAT
                     HFMMNGGNIVTLQRILGHATIQQTMTYAHFSPDFLLDAINFNPLAESVHKLSID"
     gene            complement(11776..12117)
                     /locus_tag="LSX49_003493"
     CDS             complement(11776..12117)
                     /locus_tag="LSX49_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7169857.1"
                     /translation="MVILSIDYAKKLRQIRKAEGLTQKQFADITGLSLATIRNYESGQ
                     KNARAKIVEAVLQVDRFEKYMLWLIKDKTLPVAGQIAPALSLDGSIQSEGDQVSIGIT
                     QKSPRSGRNVG"
     gene            12222..12743
                     /locus_tag="LSX49_003494"
     CDS             12222..12743
                     /locus_tag="LSX49_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL7169858.1"
                     /translation="MRDFIADKELSDHQPLQESDALSGSIDAANDDEHEENKKKRSYK
                     KGATLRLDGPIAGLCSLEKGAAYIGLTKSALRVAIHRGQMPGHKTRTNPEDENSDGVW
                     WFNAKEWDKLADELPEHEPPEWHNWKSYWTYDRQKRKFSPANKEDCQTINGKRVYTGR
                     SSKLDQLRNNRGN"
     gene            12748..13170
                     /locus_tag="LSX49_003495"
     CDS             12748..13170
                     /locus_tag="LSX49_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169859.1"
                     /translation="MKTNTSDFTITISKNDQALIDNLKYLAEKHNNGRIAINLRHITG
                     VTIVTSYWHLYLIAKSVLENKDSVVNGRDIDTLPAQIKPIAYQLRNRFKNEGGIIFDF
                     PAAVAVSFSRGDILHSFRFALSGDETLWQLEDAGSSPA"
     gene            complement(13177..13368)
                     /locus_tag="LSX49_003496"
     CDS             complement(13177..13368)
                     /locus_tag="LSX49_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169860.1"
                     /translation="MSEDKKVVNLLSELSAALDNINPPRVKTTGDKDALNTEIHILLA
                     LVTDKIQRKYPPVTQLVDF"
     gene            13506..13856
                     /locus_tag="LSX49_003497"
     CDS             13506..13856
                     /locus_tag="LSX49_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4761 family protein"
                     /protein_id="HBL7169861.1"
                     /translation="MKLQRNSSQQRFRNGAERHANRFATSASRSNSRYSLSETHATPD
                     GYPVKQIGEHTWLIEKAGIVVHRCQRNPFTGNRIFALSNGDNQFGQDFTLYEALRTVD
                     RLLHGQSFIKQADL"
     gene            13867..14145
                     /locus_tag="LSX49_003498"
     CDS             13867..14145
                     /locus_tag="LSX49_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169862.1"
                     /translation="MTKEHAQGVFIRFIDFRGELLLRASAIDGVVPSEKNAATYVYLN
                     GTRLTVELPYQTVHEIISEAEKARKTNGDEPYIEIICMDSEAEIQKAD"
     gene            14157..14399
                     /locus_tag="LSX49_003499"
     CDS             14157..14399
                     /locus_tag="LSX49_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4754 family protein"
                     /protein_id="HBL7169863.1"
                     /translation="MGKEYKTLINKALERFYFRLSASGAHAERAARDSLTRAIRSLYD
                     VAFYADDLDALNELSELICAAECGEHIEPYKLGNIA"
     gene            14396..14509
                     /locus_tag="LSX49_003500"
     CDS             14396..14509
                     /locus_tag="LSX49_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169864.1"
                     /translation="MSIFMSWIVLIISVVCAIGIVRIIHSVKKIERFFTGE"
     gene            14603..15013
                     /locus_tag="LSX49_003501"
     CDS             14603..15013
                     /locus_tag="LSX49_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001376666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169865.1"
                     /translation="MHAKEEGIIRALKEISKTENEVAKKAIANNHMDVATHTLIVARV
                     TAEAAEIIAKQDAELAVLRTQPVTGLDLSNTGRLIYTIGSELQRYTIIAGLQDKYLIT
                     PHPIRESEILTNLRLIERSQVAFIDDAQCTVFNA"
     gene            15037..15240
                     /locus_tag="LSX49_003502"
     CDS             15037..15240
                     /locus_tag="LSX49_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169866.1"
                     /translation="MAIKHFPVVRFTSRGREYEVDERLITTIDKHRSEKDAHHIYLTD
                     GTYFCATNVARVNLIRQVQEPRR"
     gene            15237..15503
                     /locus_tag="LSX49_003503"
     CDS             15237..15503
                     /locus_tag="LSX49_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL7169867.1"
                     /translation="MTILDYIATHPGCSGGEIAAALNTPTTAINAELRQLWRGGLVIR
                     TNRSTGGRARKTGGQASYHVNPMPFGCSNPLTHMFNQLLKEART"
     gene            15500..15799
                     /locus_tag="LSX49_003504"
     CDS             15500..15799
                     /locus_tag="LSX49_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169868.1"
                     /translation="MSTINHQKLRELAFALQRMATPQKLLAFRAMLSPSAALALLDEL
                     EHARTTAPAIRLTLHHEIADFCATLEVPGEPETPEAIQQELLQRIDKVFDFFLNQ"
     gene            15811..16428
                     /locus_tag="LSX49_003505"
     CDS             15811..16428
                     /locus_tag="LSX49_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HBL7169869.1"
                     /translation="MHTQKNRLPCRNQSGYISAAPHKTGAGFRSLLTTQAHNRASGFF
                     VRTVLPRFFRVRIMAGRTGPTSVGPGSCVAGTANLVRLATHSFAALDGEFSQLTTQGA
                     TPWQTANSTALSRSVVTSRLKSTADFPAHHASRKSCTSICCMSAATHYQTFIPPLFSA
                     IWRMICTSFNSSSSSKTNSINSCSGPFLHLAAGGLRTSVTRGLPQ"
     gene            16425..16790
                     /locus_tag="LSX49_003506"
     CDS             16425..16790
                     /locus_tag="LSX49_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169870.1"
                     /translation="MILANDFLEYLLNTERDLAARVRDRYDMYLKSLPVPQLADGKIV
                     IDGRYMIDSHEGNYRLYRIEGGTPSVIGIYQRPSSAIVDVIADSIRITHRHADTEDTV
                     LEIQRLATVCRDTLNGMTK"
     gene            16797..19619
                     /locus_tag="LSX49_003507"
     CDS             16797..19619
                     /locus_tag="LSX49_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HBL7169871.1"
                     /translation="MTAEYLRDWQQPRHAVGREGTGIPAPESALSSWLDAYRAENERR
                     QEMADAAFSATPLGNLINKSLDAQEKQDKTITLAGDARKQARGAVDEAMASLRLLPSY
                     LRDPLIRHLSFLRKKQEADRRKGKKSWQAERYARGTLRKIFERLDSTDGRWLTPGYRS
                     LAGRERLDDLLYLPQLNKHQIQTLATMTAAMFSSTFEKLCDGFGATDGELTMDVTLKA
                     YQMLARMALHLHAMPPHYDALTTDKDRRNEPDTELLPGAILRLTCAEWWKRKLWLLRC
                     EWREEQLRAACLVSRKTSPYLSQDALSEFRAQREKTRDFLKSFMLENEDGFTIDLETV
                     YYAGVSNPVHRKAEMMATMKGLELLAEARGDKAVFLTVTCPSKYHATTENGHPNPKWN
                     GATMRDSSDYLVNTFFAAVRKKLNRDGLRWYGIRTVEPHHDGTVHWHMMVFAHPEEID
                     TIVSHTRDIAIQEDRHELGNDITPRFKVEYVDGSKGTPTSYIATYIGKNLDSRAVDGI
                     DPKTGKPRVDHETGKSMAESVERAIGWARLHRVRQFQFFGIPSRQVWRELRRLASQMA
                     RNPEGPQRLKDDAMDAVLAAADAGCFATYIEKQGGVLVPRKDYLIRTAYDLADELNDY
                     GEQSVQIYGIWSPLIGESSRVCTHPDNWKLVRRKPEAEDSARENGFDLQGGPAAPWTR
                     GNNCPRVQETDNNGTEQPEERPAPWPQLPDGVEVNEWMRSLKRHERRALMRSLRDKQA
                     KNSSDEMQSWTQSRKQQRPLPDNHELLAKEWRESAESLGLHIGEQQMQHLLRGGSLYV
                     DGSIIAPQGFEIVRKPDTRPDSRITQLWQRLSRNHGVSSTEIRHNPVASYLAQLGASD
                     PEAAARLASTLQQGQNTMKTPVTVLSDMLRAIRDAEHAQRISETTERASRKADLLRGG
                     LTSGNKKQTETGLTNPVNEQKTRSDI"
     gene            19696..20655
                     /locus_tag="LSX49_003508"
     CDS             19696..20655
                     /locus_tag="LSX49_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HBL7169872.1"
                     /translation="MKICIDDGSTNIKLAWTENGERRNAISPNSFKSEWSAPFGGMQP
                     ANYMLDGVRYGFDPVSDRFVQTTDTQYQYSDVNVIAIHHALVKSGITPQEVDVVVTLP
                     LSEYFDTNAQPDMANINRKKANVMRPVEYQNGEAFTIRNVRVMPESIPAGFKALADMS
                     PFESLLIVDLGGTTLDVAKVQGQLAGISQVFCDPHVGVSLMADAVLSVMATNGMRTSH
                     HIANTIIEHRHDEAWLRQHIHNDAHYASLMAVIREKEETLKQRVIRALAVFSGYGRVM
                     VVGGGAEIVAPAIREVCGVNATFIADGVPQFALVNGLYAMDKE"
     gene            20660..>20938
                     /locus_tag="LSX49_003509"
     CDS             20660..>20938
                     /locus_tag="LSX49_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HBL7169873.1"
                     /translation="MTTPTRRISFYLKPAAVKSEQEACNYLDSLPASERSRAQRAAFL
                     AGLALIKRNPAFAYWMAEWPEDNLPFNTVSIKETYQDNQPSGVECNFYK"
BASE COUNT         5591 a         5526 c         5059 g         4762 t
ORIGIN      
        1 actccgtatt tgcataaaaa ccatgcgagt tacgggccta taagccaggc gagatatgat
       61 ctatatcaat ttctcatcta taatgctttg ttagtatctc gtcgccgact taataaagag
      121 agagttagtg tgaaagctga caaccctttt gatcttttac ttcctgctgc aatggccaaa
      181 gtggccgaag aggcaggtgt ctataaagca acgaaacatc cgcttaagac tttctatctg
      241 gcgattaccg ccggtgtttt catctcaatc gcattcgtct tctatatcac agcaaccact
      301 ggcacaggta caatgccctt cggcatggca aaactgattg gcggcatttg cttctctctg
      361 gggttgattc tttgtgttgt ctgcggagcc gatctcttta cttccacagt gttgattgtt
      421 gttgccaagg cgagtgggcg catcacctgg ggtcagttgg cgaaaaactg gctaaatgtt
      481 tattttggca acctggtcgg cgcactgctg tttgtacttt taatgtggct ttccggcgag
      541 tatatgaccg caaatggtca atggggacta aacgtcctac aaaccgccga ccacaaagtg
      601 caccatactt ttattgaggc cgtctgtctt ggtatcctgg caaacctgat ggtatgtctg
      661 gcagtatgga tgagttattc tggccgcagc ctgatggaca aagcgttcat tatggtgctg
      721 ccggtcgcga tgtttgttgc cagcggtttt gagcacagta tcgcaaacat gtttatgatc
      781 ccgatgggta ttgtaatccg cgacttcgca tctccggaat tctggaccgc tgtcggttct
      841 gcaccggaaa atttttctca cctgaccgtg atgaacttca tcactgataa cctgattccg
      901 gttacgatcg gtaatattat cggcggtggt ttgttggttg ggttgacata ctgggtcatt
      961 tacctgcgtg aaaacgatca ccattaatgg ttgtcgaagt acgcagtaaa taaaaaatcc
     1021 acttaagaag gtaggtgtta catgtccgag cttaatgaaa agttagccac agcctgggaa
     1081 ggttttacca aaggtgactg gcagaatgaa gtaaacgtcc gtgacttcat tcagaaaaac
     1141 tacactccgt acgagggtga cgagtccttc ctggctggcg ctactgaagc gaccaccacc
     1201 ctgtgggaca aagtaatgga aggcgttaaa ctggaaaacc gcactcacgc gccagttgac
     1261 tttgacaccg ctgttgcttc caccatcacc tctcacgacg ctggttacat caacaagcag
     1321 cttgagaaaa tcgttggtct gcagactgaa gctccgctga aacgtgctct tatcccgttc
     1381 ggtggtatca aaatgatcga aggttcctgc aaagcgtaca accgcgaact ggacccgatg
     1441 atcaaaaaaa tcttcactga ataccgtaaa actcacaacc agggcgtgtt cgacgtttac
     1501 actccggaca tcctgcgttg ccgtaaatcc ggtgttctga ccggtctgcc agatgcttat
     1561 ggccgtggtc gtatcatcgg tgactaccgt cgcgttgcac tgtacggtat cgactacctg
     1621 atgaaagaca aacttgcaca gttcacctct ctgcaggctg atctggaaaa cggcgtaaac
     1681 ctggaacaga ctatccgtct gcgcgaagaa atcgctgaac agcaccgcgc tctgggtcag
     1741 atgaaagaaa tggctgcgaa atacggctac gacatctctg gtccggctac taacgctcag
     1801 gaagctatcc agtggactta cttcggctac ctggctgctg ttaagtctca gaacggtgct
     1861 gcaatgtcct tcggtcgtac ctccaccttc ctggatgtgt acatcgaacg tgacctgaaa
     1921 gctggcaaga tcaccgaaca agaagcgcag gaaatggttg accacctggt catgaaactg
     1981 cgtatggttc gcttcctgcg tactccggaa tacgatgaac tgttctctgg cgacccgatc
     2041 tgggcaaccg aatctatcgg tggtatgggc ctcgacggtc gtaccctggt taccaaaaac
     2101 agcttccgtt tcctgaacac cctgtacacc atgggtccgt ctccggaacc gaacatgacc
     2161 attctgtggt ctgaaaaact gccgctgaac ttcaagaaat tcgccgctaa agtgtccatc
     2221 gacacctctt ctctgcagta tgagaacgat gacctgatgc gtccggactt caacaacgat
     2281 gactacgcta ttgcttgctg cgtaagcccg atgatcgttg gtaaacaaat gcagttcttc
     2341 ggtgcgcgtg caaacctggc gaaaaccatg ctgtacgcaa tcaacggtgg cgttgacgaa
     2401 aaactgaaaa tgcaggttgg tccgaaatct gagccgatca aaggcgatgt cctgaactat
     2461 gatgaagtga tggagcgcat ggatcacttc atggactggc tggctaaaca gtacatcact
     2521 gcactgaaca tcatccacta catgcacgac aagtacagct acgaagcctc tctgatggcg
     2581 ctgcacgacc gtgacgttat ccgcaccatg gcgtgtggta tcgctggtct gtccgttgct
     2641 gctgactccc tgtctgcaat caaatatgcg aaagttaaac cgattcgtga tgaagacggt
     2701 ctggctatcg acttcgaaat cgaaggcgaa tacccgcagt ttggtaacaa cgatccgcgt
     2761 gtagatgacc tggctgttga cctggtagaa cgtttcatga agaaaattca gaaactgcac
     2821 acctaccgtg acgctatccc gactcagtct gttctgacca tcacttctaa cgttgtgtat
     2881 ggtaagaaaa ctggtaacac cccagacggt cgtcgtgctg gcgcgccgtt cggaccgggt
     2941 gctaacccga tgcacggtcg tgaccagaaa ggtgctgtag cgtctctgac ttccgttgct
     3001 aaactgccgt ttgcttacgc taaagatggt atctcctaca ccttctctat cgttccgaac
     3061 gcactgggta aagacgacga agttcgtaag accaacctgg ctggtctgat ggatggttac
     3121 ttccaccacg aagcatccat cgaaggtggt cagcacctga acgttaacgt gatgaaccgt
     3181 gaaatgctgc tcgacgcgat ggaaaacccg gaaaaatatc cgcagctgac catccgtgta
     3241 tctggctacg cagtacgttt caactcgctg actaaagaac agcagcagga cgttattact
     3301 cgtaccttca ctcaatctat gtaattagat ttgactgaaa tcgtacagta aaaagcgtac
     3361 aataaaggct ccacgaaagt ggggcctttt ttagcacgag agcctttttt gtcagctatc
     3421 tatactttaa ggtgactgcc aaaacagact cgacgtagcc ttcgagctgc gcaccaacac
     3481 ggcctcagat gggccacatc tggagaaaca ccgcaatgtc agttattggt cgcattcact
     3541 cctttgaatc ctgtggaacc gtagacggcc cgggtattcg ctttatcacc tttttccagg
     3601 gctgcctgat gcgctgcctg tattgtcata accgcgacac ctgggatacg catggcggta
     3661 aagaagttac cgttgaagat ttgatgaagg aagtggtgac ctatcgccac tttatgaacg
     3721 cttccggcgg cggcgttacc gcatccggcg gtgaggcaat cctacaagct gagtttgttc
     3781 gtgactggtt ccgcgcctgc aaaaaagaag gcattcatac ctgtctggac accaacggtt
     3841 ttgttcgtcg ttacgatccg gtgattgatg aactgctgga ggtaaccgac ctggtaatgc
     3901 tcgatctcaa acagatgaac gacgagatcc accaaaatct ggttggagtt tccaaccacc
     3961 gcacgctgga gttcgctaaa tatctggcga acaaaaatgt gaaggtgtgg atccgctatg
     4021 ttgttgtccc aggctggtct gacgatgacg attcagcgca tcgccttggt gaatttaccc
     4081 gtgatatggg caacgttgag aaaatcgagc tcctccccta ccacgaactg ggcaaacaca
     4141 aatgggtggc aatgggtgaa gaatacaaac tcgatggtgt taaaccaccg aagaaagaga
     4201 ccatggaacg cgtgaaaggc attcttgagc agtacggtca taaggtcatg ttctaatttc
     4261 cccgtaaagc ggcaacttta ttgagttgcc gcttttttgt gcacagaaaa gcagagtgtg
     4321 aaacagtaag ttcacactct gcttgaattc atttacacgt gagccacggg tttcggcgta
     4381 tggccggcgt tgcgaagcag catcagcaaa tagataaacg atacgctggc gatcatgata
     4441 aacaataaat tatcggagaa attctgcatt agcatagcgg taaatgacgg gccaagcagg
     4501 cttcccacgg tatagctcaa cagtaaggcc tggttcatcg ccaccagttg atgatgttca
     4561 actttctcac aagcccaggc catcgccacc ggatatagcg taaagccagc ggcaccgagg
     4621 atgaataacg ctggggccat cgccgcctgg ctaagcatcg caatactgcc gagaatgacg
     4681 acaaagacct gaacacgcaa caccagcagt cgaccaaact tatccgccag acgtccaatc
     4741 ggccattgtc cgaggatacc cgcactgacc agtaccgcca tccagaaacc aatgctggca
     4801 ttgctcaccc ctttgtgatt gaggtacagc ggcatcaggc catatagaga tcccagcacg
     4861 attcctgaga taatgcagcc attcacgcca agccgcgcct gacggagttt tagcattgac
     4921 gtaattgacg tcgaatcatg gttttcagtc tgctgattca ggacacgcgt aaacaacagc
     4981 ggtaagattc ctgccaacgt caaacctgta acccacggca atacactcat caactcggtt
     5041 gagactttgc tgaccagtaa ctggcctaaa aacgttccga cgtaataaac catcatatac
     5101 gcagcaagca accgcccgcg gttacgcgac gtcccactgc acatcagcgc actctcaaca
     5161 accacccaaa tcatggcaca gccgatgcca gcgacaaaac gccacgccaa ccaactccag
     5221 aatccaatca tcaggccaag gccggcacag ccagcggcaa aaatgaagga ggccagataa
     5281 tagctgcggt taaagccaat gcgtttaatg acataccctg tcagcaatgt accgacaagg
     5341 ttgccggtaa aataggatga gctgacaacg cctacctgcc atgtagacat gtgttcctgg
     5401 gcgagccaaa gcggcacgag tgtatttaac accgcgatcg ccagagtcaa caaaagcagg
     5461 ccagacagca aaagcatgac aggccgggta tacgtggaca tgaattaaaa ccgtgaggaa
     5521 gttcaaattt catgcgcatc atgccaccgc caaaaacatt gtcaatgggt gaaaatacgc
     5581 gcatatcgca gcggcggtat tatcgattta tattactcat tcataacgct aatgctgaag
     5641 agacgattaa tctcatctga ttgtttttat tgatctaaca caaatttcat acgcttcgtt
     5701 cagtcgaaaa atttcatggt cacagcaaac tcatatttcc cgtctatgct ttcagagcaa
     5761 tgcatcgcgt ctgaccgatt tagacgtacc actgactctc gaaaggagaa gaggatgacc
     5821 aaaccgtatg ttcgtcttga taaaaatgat gctgccgttt tgcttgttga tcaccaggct
     5881 ggtttacttt cccttgtacg ggatatcgaa cccgataagt ttaaaaataa cgtgctggcg
     5941 ctgggtgacc tggctaagta tttcaactta ccaactattc ttaccaccag ttttgaaacc
     6001 ggtcctaacg gcccattagt tccagaactg aaagcacaat tccccgatgc accttacatt
     6061 gctcgcccgg gaaatattaa cgcctgggat aacgaagatt ttgtaaaagc tgtcaaagcg
     6121 acaggtaaaa aacagttaat tattgccggt gtggtaaccg aagtttgcgt ggcattcccg
     6181 gcgctttcag ccattgaaga agggtttgac gtctttgtcg tgactgacgc gtcagggacc
     6241 tttaatgaaa ttacccggca ttcggcatgg gatcgcatgt cgcaagctgg tgcgcaattg
     6301 atgacatggt tcggcgtggc gtgcgagctg catcgcgact ggcgtaatga tattgaagga
     6361 ctggcgacgt tgttctctaa ccacattcct gattatcgta acttgatgac cagttatgac
     6421 acgttaacga agcagaaata aaagcgaacc ggggccgaaa ccccggttgt tactgattaa
     6481 tttgcgacag ccatccccac ggtcatatgc aaaccataga atacgccacg accgattaat
     6541 tcccctgcca gaagcagaat gaatgataca gaaagtagcg gaaccgcagg ctgataacct
     6601 tttagctgtg gtgcaatcca cacgcacagg gcaacggcca aaagcacgat ccgccaggac
     6661 atcagcgcac catagtccgg caccagcgct gcggcctgct gcacagagct atgaatagtc
     6721 gccagctctg cgccctgcat cactgacatc acgccactca ctaccagtgc cagaacagaa
     6781 atggctggca gcagacgcat cgcccagcca tcgacgccag ccagactcag caacaggtaa
     6841 cccagtaacg ggccgcccat aaacatcgtc aggaagaagc ccatcggtgt ccagatgctg
     6901 taccaggtgg gtactgtatc gatgctgtta tacacacgca ccatcatcca gacaaagact
     6961 acgccaagaa ccatcgtcac caccagccaa agcgtacgca atgccggtga aagctttttc
     7021 agcattgcca gcaaccagcc gatgccgcct acagcaaaaa agatcgaacc gctggcgatt
     7081 tcgttactga gtgctgaagc ccctacccga ttgagcgagt taaaagcgcg catcggtgaa
     7141 ccaagatgaa gcatagagga gataaagcca atgcccatca gcacccataa acccaacatg
     7201 caggcgataa cacgctgctg ggcttctgct cgcaggtcgc ctttgagcag cgccaaagcc
     7261 agaacgataa aaccacccgc gacacattgc ccgaagaccg tgaagatcat cagcggccat
     7321 tcatgccatc cacttcccat ctcacacctc cttcgggttt gccagatagc cagtggtatc
     7381 cccggttggg cggctgttgg cattgggttt gatcacaata ttcggtttgg taaagtgagc
     7441 tcgcggcaac ggcgcaacgg ccgccagatc gccatgtttt ttacgcagct cgtcgatagg
     7501 gccgaaatcc agcgcccgta gcgggcagga ctctacgcag atcggttttt ttccctccgc
     7561 aacacggtca taacaaccat cgcatttggt catatggcct ttcgtttcgt tatattgcgg
     7621 tgcgccatac gggcaagcca tatgacagta acggcagcca atgcatacat cttcatcgac
     7681 cacaacaaaa ccatcttcac gtttatgcat cgcaccgctc gggcagactt tagtacaagc
     7741 cggatcttcg cagtggttac atgaaatcga cagatagtag gcaaacacgt tctggtgcca
     7801 gacaccgtta tcttcctgcc agtcgccacc agcatattca taaatgcggc ggaagctgac
     7861 ttctggcgtc aaatctttgt agtctttaca agccagctcg caggttttgc aaccggtgca
     7921 acggctggaa tcaataaaaa atccatactg ggttgtcatc ggttactcct tacacctttt
     7981 caacctgaac aaggtttgta tgtgacggat tccccttagc gagaggagac ggacgttgag
     8041 tggtcagtac gttaatacaa ccgcccttat cgacacgttt tgtatccggg tcataccagg
     8101 caccttcacc cagtgcgacc acacccggca tcattcgtgg cgtcactttc gcctcaatat
     8161 gaacctcacc acgatcgtta aagatcctga ctttatcgcc gttgttgata ccgcgttttt
     8221 gcgcatcaag cgggttgatc cacatttcct gacggcaagc tgctttcagc acatcaacgt
     8281 tgccgtaagt tgagtgaacg cgagatttat agtggaaacc cgtaagctgc agcggatact
     8341 gtttgttcag cggatcctga taactttcaa aacccggcgt atagatcggc agtggatcga
     8401 tcacatcacc ttctggcaat tcccaggtag cggcaatgtc agccagcgcc tgcgaataaa
     8461 tctcaatttt ccccgatggc gtggtcagtg gatttgcctg cggatcttca cggaaagctt
     8521 tataagcaac gtgatgccct tgtgggtcgc gctttttaaa aatcccctgc ttacggaact
     8581 cttcaaacgt tggcagttca ggaatcgctt cccgcgactg ggcatacaga tgccgcatcc
     8641 actcttcctg ggtacggccc tcagtaaact gttgctcaac gccaagacgt tttgccagtt
     8701 cgctggtcat ttcatagatg gtcttacatt caaagcgcgg tttaatcacc tgatcgttga
     8761 aaatcacgta agacatattc ccgcaggatg catccagtgc aaagtccatc tgttctgaag
     8821 cggtgcagtc aggcagcagg atgtcagcat atttcgccga tgaggtcatg tggcagtcga
     8881 taaccacaat cagctcgcac ttcttatcat cctgaaggat ttcatgggta cggttgattt
     8941 cagaatgctg gttaatcagg cagttaccgg catagttcca gatcattttg atcggcacat
     9001 ccagcttatc tttcccgcgc acaccatcac gcagcgctgt catttccggg ccacgttcaa
     9061 tggcatcggt ccacataaac atcgaaatgc tggtctggat cgggttttcg agggtcggca
     9121 tacggacaaa cggtaagctg tatgaacctt cacgcgcgcc gctgttgcct ccgttaatac
     9181 caacgttacc ggtcagaatc gccagcatcg agatagcacg ggttgcgatt tcaccgttag
     9241 cgtgacgctg cgggccccat ccctggctga taaacgccgg tttggtacta ccgatttcac
     9301 gagccaattt gatgattttg tctgccggaa caccagtgat ttgcgaggcc cattccggcg
     9361 ttttagccac gccatctggc ccttcaccca gaatataagc tttatagtga ccatttttcg
     9421 gcgcactggc tggcagtgtt ttctcgtcgt agccaacgca atatttatcg aggaatgcct
     9481 gatccaccag gttttcggtg atcatgacat acgccagacc gttaaccagt gcggcatctg
     9541 ttcccggacg aatagggatc cactcatctt cgcgcccggc accggtgtcg gtatagcgcg
     9601 gatcgatgat gatcatgcga gcattagatt tctggcgcgc ctgttcaaga tagtaagtca
     9661 ccccaccgcc actcattcgc gtttcgccag ggttattacc aaacagcact accagtttac
     9721 tgttttcgat atccgacggg ctgttaccat ctgcccagcc gccgtaggta tagttcaaac
     9781 cttccgcaat ttgcgcggaa gagtagtcac cgtaatggtt cagataaccg ccgcagcagt
     9841 tcatcaggcg cgcgaccagg gtatttcccg gcggccagga gcgggtcatg gtgccaccca
     9901 gcgtaccggt gccatagttc agatagatgg attcgttgcc gtactctttg atcaggcgct
     9961 gcatattggt cgcgatgatg tcgtaggctt cttcccagct aatgcgctcg aatttgcctt
    10021 caccgcgcgc cccgactcgt ttcatcggat atttcaggcg gtcgggattg taaacgcggc
    10081 gacgcatgga acgaccacgc agacaggcgc gcacctggtg caggccgtca tagttgtcat
    10141 cgccagtatt atccgtttca acatatttga tttcaccgtc cacgacgtgc atacgtagcg
    10201 ggcagcgact accacagtta actgtacagg cgctccagat aaccttttcg tctgattttg
    10261 ttggaatggc gctatcgaca gcgtgcgcaa tccgactaaa aggtaatgtt aatgcgctgc
    10321 tggccattgc caggccgccg atcgctgtcg tttttaccaa accacggcga ctcacctcag
    10381 cagccaatac cgcatcaggg attttcgttt tcataatggc tcactcaagc ttgctcacga
    10441 ttgattccag taacaaaccg tattgtgtaa ttatttctat agcagatcgc tatataggct
    10501 tgtatacatc gaataatttg aaaatcaaag agataggtgg attttcactc gaaagtagta
    10561 ttacttgtaa gtgaggagta attattgttc ggtatcaaag ggagacaaaa aaagcgcccg
    10621 caggcgcttt aacgtttctt gcccctcctg atgatttact tatttttcaa cgaataagcc
    10681 aaaacagggg gaacaaatta acacaaatta taactaatcg atggacagtt tatggacact
    10741 ttcagccagc ggattaaagt tgatcgcgtc cagtaaaaag tccggcgaaa aatgagcgta
    10801 cgtcattgtt tgctgaatcg ttgcgtgccc caggattcgt tgcaacgtaa caatatttcc
    10861 gccattcatc ataaagtgtg tggcaaatgt atgacgcatg acatgcgtag cctgcccctt
    10921 cggcaaatcc ggtttcacct cctgaagaat ctcccggaac ttcagataat caacctgata
    10981 caataacccc gttcgacggg ttttaatcag aggcacgacc gaatccgcca caggaaccga
    11041 acgggatttt ccgtttttgg tgttaaagaa cgtcacccgg ttgccaacga tatgctctcc
    11101 acgtagttcc gatgcttcac tccatcgggc accagtagaa agacacagaa tggcaacacg
    11161 acgcacatca ccctccagtc gctcaagaag ccgttcaatc tcatcatcag aaagaaaggc
    11221 catctctgtg ttctgaactt tcagttttcg tataccgcgt acagggttcg cgttgtgaaa
    11281 gacctcagct tcaatcagca ccgtgaacat ggtagacagt acgcataagt cacgattaat
    11341 actggacggc attaatccgg cctgtaattt ctctgaccga tattcaagca taaattttcg
    11401 cgtcatctga ctggcgcgag gatctcccat ttcacgaaca accttcccta gcctaaccct
    11461 gtagctatcc ccgtaagcct gattacgccc atcaagcatc caccacgcat caagcagctc
    11521 tgataatcgc cgctgatcag ctggcttagc ctgccatggc ttgtcatgaa agttctgtaa
    11581 cacatacttc tcaaactcct gagcctttga tttcagggca aagatttttc gaatccgctt
    11641 tccttccgcc ccctgcggtc tgacatcgac ctgataacgt ccgtctttga gttgcttaat
    11701 cgacatgatt agcccctcca acggataaat taactaaaca ctccttgcga tatgtaattc
    11761 gctcaatgtg tagagtcagc caacattgcg gcctgatcgg ggtgattttt gggtaatacc
    11821 gattgaaacc tgatcgccct ccgactgaat agatccatca agagagagag ccggagcaat
    11881 ctgcccggcg acaggtagcg tcttatcttt tattagccac agcatgtatt tttcaaagcg
    11941 atcgacttgc agaaccgcct caacgatttt tgctctagcg ttcttttgcc ccgattcgta
    12001 attccttatg gttgccaaag acaacccagt aatatccgca aactgctttt gtgttaaccc
    12061 ttccgcctta cgtatctgac gtaacttttt tgcgtagtct attgacaaga taaccatttg
    12121 agtattaacc tctcgcacaa agataacctt ttggttatct ttacaagcca aaacaaacca
    12181 tcacaaggcg cgacaagcgc accaacgcaa gaggataaca aatgcgggac ttcattgccg
    12241 ataaagagtt atctgaccac caaccacttc aggaaagtga cgcactcagc ggatccattg
    12301 atgccgccaa cgacgacgag cacgaagaaa acaagaaaaa gcgttcctac aaaaaaggag
    12361 cgactttgcg gctggatggt ccgatcgccg ggctttgctc tctggaaaaa ggcgcggcat
    12421 atattgggct aacaaaatct gcactgcgcg tagccattca tcgcggtcaa atgccgggac
    12481 acaagacgcg cacaaacccg gaagatgaaa actcagacgg agtatggtgg tttaacgcca
    12541 aagagtggga caagttggct gatgagctac cagagcacga gcccccagaa tggcacaact
    12601 ggaaaagtta ctggacgtat gaccgccaga aaaggaagtt ctctccagct aataaagaag
    12661 actgccagac cattaacggt aagcgagttt atacaggcag aagctcaaaa ctggaccaac
    12721 tcagaaacaa cagaggcaac taatcgtatg aaaacaaaca cgtcagattt cacaataact
    12781 atttcaaaaa atgaccaagc attaattgat aacctgaaat accttgcgga aaaacataat
    12841 aacggacgaa ttgcaattaa tttacgacac atcacaggag taacaattgt aaccagttac
    12901 tggcatctat atctaatcgc taaatcagta cttgaaaaca aagattctgt tgtcaatgga
    12961 agagatatag atactcttcc tgcacaaatc aaaccgatag cctatcaatt gcgtaatcgt
    13021 tttaaaaatg aaggtgggat tatatttgac tttcccgcag ctgtagccgt gagcttctct
    13081 cggggggata tacttcactc atttcgtttt gctctatcag gtgacgagac attatggcag
    13141 ctagaagatg ccgggagcag cccggcataa atcaaattaa aaatcaacca gttgtgtgac
    13201 aggtgggtat ttacgctgaa ttttgtcagt tactaacgcc agtaatatat gaatctctgt
    13261 gtttaatgcg tctttatcac ccgtcgtttt taccctggga gggttaatgt tatccagagc
    13321 agcactaagt tcactcaaca aattaacaac ttttttatct tctgacatga aaacctctta
    13381 acaatttaat taaacataag ccaggacctg aaccggccag tccaagtcct agacacacaa
    13441 aaaaaatacc acaaatcaat acaaggtgac acgagtacac cttaccgaag gtacagagtt
    13501 ttaatatgaa actacagcgc aattcttcac agcagcgctt ccgcaacggt gcggaacgcc
    13561 atgctaaccg tttcgctacc agtgcatcac gtagcaactc tcgctacagc ctgagcgaaa
    13621 cacacgcaac gccggatggc tacccagtaa aacaaattgg tgaacacact tggctgattg
    13681 aaaaagcagg aatcgtggtt cacagatgcc agcgcaaccc atttaccgga aaccgcattt
    13741 ttgcactgag caacggcgac aatcagttcg ggcaggattt cacattatac gaagcacttc
    13801 gcacggttga tcgtctgctt cacgggcaaa gttttattaa acaggctgat ttataacagg
    13861 tgctttatga ccaaagagca tgcacaaggt gtatttatcc gttttattga ttttcgcggt
    13921 gaactgttat tacgcgcatc agccattgac ggagttgttc catccgaaaa aaatgcagct
    13981 acttacgttt atctgaacgg cacgcgcctg accgtagaac ttccgtacca gactgtacac
    14041 gaaatcatta gcgaagcgga aaaagcacgt aagactaatg gcgatgaacc ctatatcgaa
    14101 attatttgta tggattcaga agcagaaatt cagaaagcag attaaagggc gttgcgatgg
    14161 gcaaagaata taaaactctc attaacaaag cacttgagcg tttttatttt cgcttaagtg
    14221 catcaggcgc tcatgctgaa cgtgcagccc gtgactcatt gaccagggca atccggagtc
    14281 tgtatgacgt ggctttttac gctgatgatc tggatgcact taacgaactt tccgagctga
    14341 tctgtgccgc agaatgcggg gaacatattg aaccgtataa gctggggaat atcgcatgag
    14401 tatatttatg tcatggattg ttctgattat ttcagtggtc tgcgcaattg gcattgtgcg
    14461 aattattcat tcagtaaaaa agattgaacg ttttttcact ggtgaataac gatacaaata
    14521 aaacatcaaa ttaaataaga aaacgtgaaa accatccgta ttaacggagg tattcgcaca
    14581 cgcaaataac ggagatacaa aaatgcacgc aaaagaagaa ggtatcatca gagcactgaa
    14641 agaaatttca aagacagaaa acgaagtagc gaaaaaagcc atagcaaata atcatatgga
    14701 cgtcgcaacc cacacactga tagtcgcaag agtcacggca gaagcagccg aaattatcgc
    14761 aaaacaggat gctgaactgg cggttctcag aacacaacca gtcaccggac tggatttgtc
    14821 taacaccgga cgccttattt acacaattgg ctcggagcta cagcgataca ccattatcgc
    14881 cgggttacag gataaatacc tgatcactcc tcaccccata agggaatcag aaattctgac
    14941 aaatctccgc ctgatagagc gctctcaagt cgcattcatt gatgacgcac agtgcaccgt
    15001 atttaacgca tagagttact ggacaaaggg ggcgcaatgg caattaagca ttttcccgtc
    15061 gttcgcttta cctccagagg gcgcgaatac gaggtcgacg aacgcctgat taccactatc
    15121 gacaaacatc gttcggaaaa ggatgcacac cacatctacc tcactgacgg cacttacttc
    15181 tgcgccacta atgtggcgcg ggtaaacctt atccgacagg tacaggagcc acgcagatga
    15241 ccattctgga ctacatcgct actcatccgg ggtgtagcgg cggagagatc gccgcagcac
    15301 tgaatactcc aaccacagcc attaatgctg agttacgcca actttggcgc ggcggcttag
    15361 tcatcagaac aaaccgcagc acaggtggtc gcgctcgcaa aactggaggc caggcttctt
    15421 accacgtaaa cccgatgccg ttcgggtgta gcaatccact tactcacatg tttaaccagc
    15481 tactgaagga agccagaaca tgagcaccat caaccaccag aagctacgcg aactggcatt
    15541 tgccctgcaa cgaatggcaa cacctcaaaa attactggca tttcgcgcaa tgctctcgcc
    15601 gtctgctgcg ctggcattgc tggatgagct ggagcacgcc agaaccacgg ctcctgccat
    15661 tcgcctgacg ctccatcatg aaatcgctga tttctgcgcg acattggagg tgccaggcga
    15721 accggaaacg ccggaagcaa tacagcaaga gctgctgcaa cgtattgaca aggtttttga
    15781 tttttttctg aaccagtaag aaaccagagc atgcacacac aaaaaaaccg cttgccatgc
    15841 cgcaatcagt caggttacat ttccgctgca cctcataaaa cgggtgccgg gtttcgcagc
    15901 ctgctgacta cacaagcgca caaccgcgcc agcggttttt ttgtgcgtac tgtattgcca
    15961 cgtttttttc gcgtcagaat tatggcgggg cgtacggggc cgacttcggt cgggccgggt
    16021 tcttgtgtag ccggtactgc gaacctcgta cgtctcgcca cccacagttt cgcagctctg
    16081 gatggtgagt tttcacaact tactacacaa ggggccacac catggcaaac cgcaaacagc
    16141 accgcgctat cgcggagcgt cgtcacatcc agactgaaat caaccgcaga ctttcccgcg
    16201 catcacgcgt cgcgcaaatc atgcacatca atatgctgca tgagcgcagc cacgcactat
    16261 caaacattta ttccgcctct gttttcagct atctggcgga tgatctgcac gagcttcaac
    16321 agctcatcca gcagcaaaac aaactccatt aattcctgtt ccgggccttt cctgcacctt
    16381 gcggcgggag gccttcgcac atctgtaaca agaggattgc cgcaatgatt ctcgccaacg
    16441 actttcttga atacctgctc aatacagaac gtgatcttgc cgctcgcgtg cgtgatcgtt
    16501 atgacatgta cctgaaatcc ctgcctgtac cgcagctcgc tgacggaaag attgttattg
    16561 atggtcgcta catgattgac agccacgagg gaaattacag gctttaccgc attgaaggtg
    16621 gcaccccgtc cgttattggc atttaccagc gcccatcctc tgcaatcgtc gatgtgattg
    16681 ccgacagcat ccgcatcaca catcgccatg ccgacacaga agacaccgtg ctggaaattc
    16741 agcggctggc tacagtctgc cgcgacaccc tgaatggcat gacgaagtaa atcactatga
    16801 cggcagagta cctcagggac tggcaacaac cgcgccacgc agtggggcgt gaaggaacgg
    16861 ggatccccgc tcctgaatcc gcgctttcct cctggctgga tgcctaccgg gcagagaacg
    16921 agcgccgcca ggaaatggct gatgcggcgt tctcagccac gccgctgggc aacctgatta
    16981 ataaaagcct ggacgcacag gaaaaacagg acaaaaccat cacactggca ggagacgcca
    17041 gaaaacaggc acgtggcgcg gtggatgaag ccatggcctc gctgcgcctg ctgccgtcct
    17101 atctgcgcga tccgcttatt cgccacctct ccttcctgcg caaaaaacag gaagccgatc
    17161 gccggaaagg caaaaagagc tggcaggcgg aacgctatgc acgcggaacc ctgcgcaaaa
    17221 tattcgaacg tctggatagc actgacggac gctggctgac accgggttat cgctcccttg
    17281 ccggacgcga acgcctggac gatttgcttt acctgccgca gctcaacaaa caccagatac
    17341 agacgctggc caccatgacg gcggcgatgt tcagcagcac cttcgaaaaa ctctgcgatg
    17401 gctttggcgc gaccgatggc gagctgacca tggatgtaac cctgaaggcg tatcagatgc
    17461 tggcccgcat ggcgttacac ctgcacgcca tgcctccaca ttatgacgca ctgacaacag
    17521 acaaagaccg gaggaacgaa ccggacacgg agctgctgcc gggcgcaatc cttcgcctga
    17581 cctgtgcgga atggtggaaa cgcaaactgt ggctgttacg ttgcgagtgg agagaagaac
    17641 aactccgcgc cgcctgtctg gtttccagaa aaacatcacc ctatctgagc caggacgcgt
    17701 taagcgagtt tcgcgcacag cgcgagaaaa cacgcgattt cctgaaaagt ttcatgctgg
    17761 aaaatgaaga cgggttcacg attgatctcg agacagtgta ttacgcggga gtaagtaacc
    17821 cggttcaccg taaggcagaa atgatggcca ccatgaaggg actggaactt ctggccgaag
    17881 cccgtggcga caaagcggtg tttctgactg tcacctgccc gtcaaaatac cacgccacaa
    17941 cggagaacgg tcatccgaat cccaaatgga acggggccac aatgcgcgac tccagcgatt
    18001 acctggttaa cacgtttttt gcggcggtcc gcaaaaaact gaaccgcgac ggcctgcgct
    18061 ggtatggcat ccgcacggtg gagcctcatc atgacggcac cgtgcactgg catatgatgg
    18121 tctttgcaca tccggaagaa atcgacacca ttgtgtccca tacccgcgat attgccattc
    18181 aggaagaccg ccacgagctg ggcaatgata ttactccgcg ctttaaggtg gagtatgtcg
    18241 acggctcaaa aggcacgcca accagctaca tcgccaccta catcggaaag aacctggaca
    18301 gccgcgccgt ggatggcatc gacccgaaaa cgggcaagcc acgcgtggac cacgaaaccg
    18361 gaaaatcaat ggccgagagc gtggagcgcg ccatcggctg ggcgcgcctt caccgggtcc
    18421 gtcagttcca gttctttggc atcccctccc gtcaggtgtg gcgtgaactg cgccgccttg
    18481 ccagccagat ggcacgcaat ccggaaggcc cgcaacggct gaaagatgat gcaatggatg
    18541 cggtactcgc tgccgccgat gccgggtgtt ttgccaccta cattgaaaaa cagggtggcg
    18601 tgcttgttcc acgcaaggac tacctgattc gcaccgccta cgacctcgca gatgagctga
    18661 acgattacgg cgaacagagc gtacagattt acgggatctg gtcaccactc atcggggaat
    18721 cctcccgtgt gtgcacgcat ccggataact ggaagctggt aagacgtaaa ccggaagcgg
    18781 aagacagcgc ccgcgaaaat ggttttgacc ttcagggcgg ccctgccgcc ccttggactc
    18841 gtggcaataa ctgtccccgt gtacaggaaa cggacaacaa cgggacagaa cagccggaag
    18901 aacggccagc accgtggccg cagctccctg acggcgttga agtgaacgaa tggatgcgct
    18961 cactgaaacg acacgaacgc cgggcgctga tgcgttcgct tcgtgacaaa caggcaaaaa
    19021 acagcagcga tgaaatgcag agctggacac agagccgcaa acagcagcgg cctttgcctg
    19081 ataaccacga attactcgct aaagaatggc gggagtctgc tgaatctctc ggcctgcata
    19141 tcggtgaaca acagatgcag cacctgttac ggggcggcag tctgtacgtt gacggcagca
    19201 tcattgcacc gcagggattt gaaattgtac gcaaaccgga tacccgcccg gacagccgaa
    19261 tcacgcagct ctggcagcgc ctgagccgta atcatggcgt aagcagcacg gagatccgcc
    19321 ataacccggt cgccagctat ctggcacagc tgggggcatc agaccctgaa gccgccgcac
    19381 gcctggcatc cacacttcag cagggccaga acaccatgaa aacacccgtt accgtgcttt
    19441 ctgacatgct gcgcgccatc cgcgacgcag agcacgcaca gagaatcagt gaaaccactg
    19501 aacgcgccag ccgcaaagca gacctgctgc ggggtggcct gaccagtgga aacaaaaaac
    19561 agacagaaac gggacttacg aatcccgtaa atgagcaaaa aacgcgcagc gatatatgaa
    19621 gcgcgcacaa aacaggcaaa aacgggattt cagaatcccg taaacgatta attaatcaac
    19681 ataaggaaaa gcgacatgaa aatttgtatc gacgacggct ccaccaacat caagctggca
    19741 tggactgaga atggcgaacg ccgcaacgcc atcagcccga acagcttcaa gtcggaatgg
    19801 tctgcgccgt tcggtggcat gcagcccgcg aactacatgc ttgatggcgt gcgctatggt
    19861 tttgatccgg ttagcgatcg ctttgtccag acgaccgaca cgcaatacca gtacagcgat
    19921 gtgaatgtaa tcgccattca tcacgcgctg gtcaaatcag gcatcacgcc acaggaggtg
    19981 gatgtggttg tcaccctgcc actgagcgag tatttcgaca caaacgcaca gccggacatg
    20041 gccaacatca accgcaaaaa agcgaacgtt atgcgcccgg tggaatacca gaacggcgaa
    20101 gcattcacta tccgtaacgt gcgggttatg cctgaatcca ttccggctgg ctttaaagca
    20161 ctggctgaca tgagtccgtt tgaatccctg ctgattgtgg atttaggcgg aaccacgctg
    20221 gatgtggcaa aggttcaagg gcaactggca ggtatcagcc aggtgttttg cgatccacac
    20281 gtaggcgttt ccctgatggc cgatgccgta ctgtcggtga tggccactaa cggtatgcgc
    20341 accagtcacc acatcgccaa taccattatc gaacatcgcc atgatgaagc ctggctgcgc
    20401 cagcacatcc acaatgacgc gcattacgcc agcctgatgg cggttattcg tgaaaaggaa
    20461 gaaacactga aacaacgcgt gatccgcgcg ctggcggttt tttcgggtta cgggcgggtg
    20521 atggttgtcg gtggaggggc ggagattgtg gcacccgcta tccgcgaagt ctgcggagtt
    20581 aatgcgactt tcatcgcgga cggggtgcca cagtttgctc tggttaatgg gctgtacgca
    20641 atggacaagg agtaaaccaa tgacgacacc aaccagacgg ataagtttct atctgaagcc
    20701 cgccgccgtc aagagtgaac aggaggcgtg caattacctc gatagcctgc cagcctccga
    20761 acgcagccgc gcgcaacgcg cggcctttct ggctgggcta gcgctcataa agcgcaaccc
    20821 agcatttgcc tactggatgg ccgaatggcc agaggacaac ctccccttca ataccgttag
    20881 catcaaggaa acataccagg ataatcagcc tagcggagtt gaatgcaatt tttataaa
//
LOCUS       DAFGPF010000085        20585 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFGPF010000085 DAFGPF010000000
VERSION     DAFGPF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20585
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.085"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(323..1987)
                     /gene="glnS"
                     /locus_tag="LSX49_003510"
     CDS             complement(323..1987)
                     /gene="glnS"
                     /locus_tag="LSX49_003510"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HBL7169874.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(2207..2968)
                     /locus_tag="LSX49_003511"
     CDS             complement(2207..2968)
                     /locus_tag="LSX49_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7169875.1"
                     /translation="MKGYNRLEQIMDYLKSHNLVTVDELVAVTNASPATIRRDLIKLD
                     EQGVISRTHGGVTLNRFIPTQPTTHEKMQRSLAEKHAIASAAASMVKAGDSVVLDAGT
                     TMIELARQITHLPLRVITSDLHIALFLAEFKQIEVTIIGGRIDDSSQSCIGEHGRKLL
                     QNTWPDVAFLSCNSWDLEKGITAPTEEKAALKRDLIAHASRKILLADSSKYGSWSLFN
                     IAHLNELTEIITDSQLDGQTRRTLASLSTRLIIAD"
     gene            complement(2970..3956)
                     /locus_tag="LSX49_003512"
     CDS             complement(2970..3956)
                     /locus_tag="LSX49_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-threonate 4-phosphate dehydrogenase"
                     /protein_id="HBL7169876.1"
                     /translation="MNNIIAVTMGDPAGIGPEIIIKSLSEAGLAGAPVVVVGCVRTLR
                     RIMAMNITPQAELRVIQKVCDAHFAPGVINVMDEPLANPDALTPGVVQAVAGDLAYRC
                     IKRATALALSGEVKAIATAPLNKEALHLGGHNYPGHTELLAHLTGSKEYAMVLYTEKL
                     KVIHISTHISLRKFLDTLNGERVKTVIRVANHFLKRVGIERPRIAVAGVNPHAGEHGL
                     FGTEEIEIIAPAIEAMQAEDIDVTGPCPPDTVFMQCHEGLFDMVVAMYHDQGHIPLKL
                     LGFYDGVNITAGLPFIRTSADHGTAFDIAWTGKAKSESMAVSIQLAMQISRE"
     gene            complement(3949..5184)
                     /locus_tag="LSX49_003513"
     CDS             complement(3949..5184)
                     /locus_tag="LSX49_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HBL7169877.1"
                     /translation="MEKGITKPSILIVADDFTGANDAGVSLAQVGHTVDVAFEMPYRG
                     DASVWVINSDSRAMDPKLAAMKITSLMSHLPLANNPPLVIKKIDSTLRGNIGAEIEAL
                     MKACGITGAVVAPAFPQAGRTTVAGECWVNGVRITETEFASDPKTPVLSARIADIIRL
                     QTAIPCQPVTVSQLSHLSYEQPWIGVIDAQTDSDLDRIAAAVMQAKQPLLLVGSAGIC
                     DAVARRSAIMPPPTVLAIIGSMSEIAQRQIATLHSHPRITQIYVDVEHILAGNASDYD
                     ARIVQALQKGDHCIVHTCNDSVARHQIDTLCQRWQMSRAALGEKICRFLGELTRQVLL
                     CAMPDALYLSGGDVAMATASALGATGFRITGKVAQCVPYGHFLGGVWSRSVMTKAGGF
                     GDETTLHQVLNFIEEKRSE"
     gene            5354..6511
                     /locus_tag="LSX49_003514"
     CDS             5354..6511
                     /locus_tag="LSX49_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBL7169878.1"
                     /translation="MVIINSTILSGAGAIPSLTSLLPDIRKMLLVTDRNIAQLDGVQQ
                     IRALLEKHCPQVNVIDNVPAEPTHHDVRQLMDALGDASFDVVVGIGGGSVLDVAKLLS
                     VLCHPQSPGLDALLAGEKPTQRVQSWLIPTTAGTGSEATPNAILAIPEQSTKVGIISQ
                     VLLPDYVALFPELTTSMPAHIAASTGIDALCHLLECFTATVANPVSDNAALTGLSKLF
                     RHIQPAVNDPQDLRAKLEMLWASYYGGVAITHAGTHLVHALSYPLGGKYHLPHGVANA
                     ILLAPCMAFVRPWAVEKFAQVWDCIPDAETALSAEEKSHALVTWLQALVNQLKLPNNL
                     ADLGVPPEDIASLSEAALNVKRLMNNVPCQLDLQDVQAIYQTLFPQHQFKE"
     gene            6515..7402
                     /locus_tag="LSX49_003515"
     CDS             6515..7402
                     /locus_tag="LSX49_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBL7169879.1"
                     /translation="MPKTIEGVLTAIVTPFTATGSLNIPALKVQVNRQLEAGNAIFCG
                     GTNGEFFVLNEQEKLSVTQTCVDEVAGRAPVVAHIGEISTRETIRLGQQIEKLGVDAV
                     SVIAPYFVPLKQEELIAHYSAIADTLSIPMFLYNIPARTGNTIQPETARALASHPNII
                     GIKDSDGSDESLKGFLDAVRDIDGFNVLNGPDSLIHKGFVEGCSACISGLANVAPREI
                     NAIWSRFHAGDIEGSYEAQESVTGLRTDLYKVAFSPAAVKKALQLMGHDVGDSRYAVN
                     FTPEQISEIQQIIRHYNIN"
     gene            7462..8220
                     /locus_tag="LSX49_003516"
     CDS             7462..8220
                     /locus_tag="LSX49_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HBL7169880.1"
                     /translation="MFLWFMQPDIWLTLITLTFLEIILGVDNIIFLSLVVAKLPLSQQ
                     NMARKLGLSCAMIMRILLLISIAWLSHITQPLFTVLTLEISFRTLILLGGGLFLIYKA
                     IQEIREELSPAQEDEHGSGSRQLSLCGAIVQIMLLDIVFSLDSVITAVGLSQHIFIMI
                     AAVMIAVGVMMFAAKTIGDFVNATPSIKILALTFLLFVGVLLVADSLNIHIAKEYLYF
                     AIFFSLSVETLNIIRERKNKKVSTLIETHESHSH"
     gene            8256..9425
                     /locus_tag="LSX49_003517"
     CDS             8256..9425
                     /locus_tag="LSX49_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000109428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HBL7169881.1"
                     /translation="MSVALIRDGVIRPSENDSHVLTAMLPSSCPQNHAANILPLPDGA
                     LMCVWFAGTQEGIADISVWGSRLPAGGMQWSDAAKLSHDDTRSEQNPVLFLAPDNVLW
                     LLWTAQISGNQDTAIVRYRKSDDLGQTWGEIATLLDKPGTFIRQPITVLDNGNWLLPV
                     FYCRTQPGEKWVGNDDISAVKISADGGHSWRDVEVPQSLGCVHMNITMLHDGTLVALF
                     RSRWADNIYISHSVDNGESWSVLQATELPNNNSSIQVTTLASGELALVYNAMSAAGAV
                     ERRASLYDEIDDGDDSRKEPTAVGRSAFWGAPRAPMTVAISADGGKSWSWRRNLDEGD
                     GYCMTNNSLEKLNREFSYPSIKQSPDGTLHIAYTWWRQAIKYVRISPEWVKGQAS"
     gene            9422..9892
                     /locus_tag="LSX49_003518"
     CDS             9422..9892
                     /locus_tag="LSX49_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBL7169882.1"
                     /translation="MIIGNLNHLSLAGLPAWVRNILLRPECSLSALSTREDGRWQPEG
                     CRWFCSLGTSDTQPAELRHTEYHHLWADIQVVITGCEGINAGTRPIARENDEERKPDL
                     FIAPSPENSVAITLHAGDFAVFMPEEPHQALCAIGTATSIRKAVFKVPRDMLEA"
     gene            9906..11186
                     /locus_tag="LSX49_003519"
     CDS             9906..11186
                     /locus_tag="LSX49_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HBL7169883.1"
                     /translation="MTMEMILALGILVLMIVLIMSDKMPFGAPPLLACLLLVVSGLST
                     VQQAFAGFVNPSVVMIAGFMVVMAALQKTRLISNVKSAMISLVNKGSYRSYGLLLVIV
                     MLGASLAGTGATGYYVLILSLVSTIPYSKKLPTSKLMMPLGFATNHPLLPINLALLFG
                     VTATVLETAGFHQAISMGRFALVNLIMSAAFLAWSLIAYRFLPDHPIADASEDALAAR
                     EETFNALPAWKEYCTIAAFAVSVIGMMLMNILGNIAFVIPGLAGAFVLMIDVLDFKEV
                     RDHMGAPVILMMAGVIGVADALAGTGFTAMVGDAVAGVLGSGVSPFVFIVAFALLTST
                     CATFTGSNMGSVYIFAPIAIAACTSLGLNPTAAAIAVVISGWNGGYMPIDGMPAMILG
                     MGKYKLPEFWVFSVPMYLIRILALCAGAVFIFPM"
     gene            complement(11275..13221)
                     /gene="nagE"
                     /locus_tag="LSX49_003520"
     CDS             complement(11275..13221)
                     /gene="nagE"
                     /locus_tag="LSX49_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HBL7169884.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVVFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLNQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVVDSARVNDAMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAEATPATAAPVAKPQAVPNAVSIAELVSPITGD
                     VVALDQIPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDD
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            13554..14354
                     /gene="nagB"
                     /locus_tag="LSX49_003521"
     CDS             13554..14354
                     /gene="nagB"
                     /locus_tag="LSX49_003521"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL7169885.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            14414..15562
                     /gene="nagA"
                     /locus_tag="LSX49_003522"
     CDS             14414..15562
                     /gene="nagA"
                     /locus_tag="LSX49_003522"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL7169886.1"
                     /translation="MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     ENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITRTIVNGNEVVTQ"
     gene            15571..16791
                     /gene="nagC"
                     /locus_tag="LSX49_003523"
                     /gene_synonym="nagR"
     CDS             15571..16791
                     /gene="nagC"
                     /locus_tag="LSX49_003523"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HBL7169887.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            16839..17591
                     /gene="nagD"
                     /locus_tag="LSX49_003524"
     CDS             16839..17591
                     /gene="nagD"
                     /locus_tag="LSX49_003524"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HBL7169888.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
     gene            17847..19511
                     /gene="asnB"
                     /locus_tag="LSX49_003525"
     CDS             17847..19511
                     /gene="asnB"
                     /locus_tag="LSX49_003525"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HBL7169889.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFEAYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
     gene            complement(19553..19990)
                     /locus_tag="LSX49_003526"
     CDS             complement(19553..19990)
                     /locus_tag="LSX49_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169890.1"
                     /translation="MLRFMTALMGALLLMQSAFADTVKPEIGKYVFGYRGQEGAVVWM
                     MRIGPKASNEALIQVSHVDNDIDGQIFRCKVKALQEGEKSYTAVIKGKSFELLRLKEG
                     NGRLHIPDEQATWLVAYSDELSNSDVANPEHFLTAYQNQQAPQ"
     gene            20324..20400
                     /locus_tag="LSX49_003527"
     tRNA            20324..20400
                     /locus_tag="LSX49_003527"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20358..20360,aa:Met,seq:cat)
     gene            20411..20495
                     /locus_tag="LSX49_003528"
     tRNA            20411..20495
                     /locus_tag="LSX49_003528"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20445..20447,aa:Leu,seq:tag)
BASE COUNT         4973 a         5347 c         5219 g         5046 t
ORIGIN      
        1 gacgcgaatt atcaatctct ttctgtaacc agaatgtaag aacatgagca accgcacata
       61 ttttgatgat ttttgttaca aggcttaagt ttgcagttga aaggcttgca gaagaataaa
      121 aacgtgaaat tccagcaaga tgaaagcggt tacattttat ttaattatgt tttgtgattt
      181 taaatttatt ttatggataa attgcgaagc ggaattaatt cgcgaagaaa agcagaaaaa
      241 aacgccgcag agcgcggcgt ttgggataat ttgcatattt cttgccggat gcggcgtaaa
      301 cgctctatcc gacaacgtaa acttactcgc ctactttcgc ccaggtatca cgcagcccaa
      361 cggtgcggtt aaataccggt ttttccgccg tagaatggcg gctgtcgagg cagaagtaac
      421 cttcacgctc aaactggaat gctttacccg caaccgcatc tttcagcgac ggttcagcaa
      481 agccctgttt gatcaccagc gattccgggt taatcaccga caggaaatca tccgcagcac
      541 cagggttcgg cacgctgaac agacggtcat acaaacggat ttcaaccggc agcgcatgtg
      601 ccgcgctcac ccagtgaata acacctttga ctttacgacc atctgccgga tctttgctta
      661 aggtgtcggc gtcataagta cagaagatgg tggtgatatt gccttcggca tctttctcca
      721 cgcgttctgc cttaatgacg taagcattac gcagacgcac ttctttaccc agcaccagac
      781 gtttgtactg cttgttagct tcttcgcgga aatcggcgcg atcgatccaa atctcaccgc
      841 taaatggcac ctgacggctg cccatttccg gtttattcgg atggttcggc atggtaacca
      901 tttcgccttc gccctggtag ttttcgataa ccagtttcac cggatcgata accgccattg
      961 cgcgcggcgc attttcgttg agatcttcac ggatgcagga ttccagtgac gccatctcaa
     1021 tggtgttgtc ctgcttggtc acaccaatgc gtttgcagaa ctcacgaata gaagccgcag
     1081 tgtaaccacg acgacgcaga ccagaaatgg tcggcatacg cgggtcatcc cagccttcaa
     1141 cgtgcttgtc ggtcaccagc aggttcagct tacgcttgga catcacagtg tattccagat
     1201 tcaggcgcga gaattcgtac tggcgcgggt gaacaggaat ggtgatgttg tccagtaccc
     1261 agtcgtacag acgacggttg tcctggaact caagcgtaca cagagagtgc gtaatacctt
     1321 ccagcgcatc gctgatgcag tgggtgaagt cgtacatcgg gtagatgcac cacttgttgc
     1381 cagtctggtg gtgttcagca aacttaatgc ggtacagcac cggatcgcgc atcacgataa
     1441 acggcgaagc catgtcgatt ttcgcacgca ggcaggcttt accttcttca aaaccgccgg
     1501 tacgcatttt ctcgaacagc gccaggttct cttcaacgct gcgatcgcgg tacgggctgt
     1561 ttttacccgg ctgcgtcaag gtgccgcggt attcgcggat ctgttccggc gtcagttcat
     1621 caacgtacgc caggccttta ttgatcagtt cgatcgcata ggcgtggagc tgatcaaaat
     1681 aatcggagga gtaacggacg ttaccagacc agtgaaaacc taaccactct acgtcgtttt
     1741 tgatcgaatc gacatactcg atatcttctt ttaccgggtt agtgtcgtcg aaacgcaggt
     1801 tgcactggcc tttatagtcc tgggcgatcc cgaagttcag gcagatagat ttcgcatggc
     1861 caatatgcag atagccattc ggctccggcg ggaaacgggt gtgtactgtg gtgtgcttac
     1921 cactggccag atcttcatcg atgatctgac ggataaagtt agtcgggcgg gcttctgcct
     1981 cactcatcgt ggattcctca aagcgtaaac aacgtataac ggcgtatgat cttataagcg
     2041 ggacaggctg acaactgtta gttagcgaaa aaatggtttt gcgtaagata ttggggcgtt
     2101 ttctgcgcta ctgccagcag atcctcgcgc tggaaacgta aggccaaacg tcgccagcct
     2161 gacgcattta ttaaatttcc ggatgagctg gccgcagagt cgtagattag tcggctatga
     2221 ttaaacgcgt cgacaaggac gcaagcgttc tacgcgtctg cccatcaagc tgactatccg
     2281 taataatctc tgtcagttca ttaagatgcg cgatattaaa cagcgaccat gaaccgtatt
     2341 ttgagctgtc agccaggaga attttgcgcg aagcatgcgc gataagatcg cgttttagtg
     2401 cggctttctc ttccgtgggt gctgtaatac ccttttcaag atcccagctg ttacagctta
     2461 aaaatgccac gtccggccag gtattttgca gcaatttacg accatgttcg ccaatgcagg
     2521 actggctgga gtcgtcaata cgtccgccga taatcgtcac ttcaatttgc ttgaattcag
     2581 ccaaaaaaag cgcgatatgc aggtcgcttg tgatcacgcg aagcggtaaa tgtgtaatct
     2641 gccgcgcaag ttcaatcatt gtcgtaccgg catcaaggac gacggaatcc cccgctttga
     2701 ccattgacgc cgctgcgctg gcgatggcat gtttttccgc caggctgcgc tgcattttct
     2761 catgggtagt cggttgggta ggaataaacc ggttgagagt cacaccgccg tgtgtacggc
     2821 tgataacacc ctgctcatcg agttttatca ggtctcgacg aatcgtagcc ggcgacgcat
     2881 tggttaccgc caccagctca tctacggtga ccagattatg gcttttcagg taatccatga
     2941 tctgctctaa ccggttatat cccttcattt tattctcgcg aaatctgcat tgctaactgg
     3001 atggaaactg ccatgctctc agacttggct tttcctgtcc aggcaatatc aaacgcggtg
     3061 ccgtggtcgg cagaagtgcg aataaatggc aacccggcgg tgatattcac cccatcataa
     3121 aatccaagca gttttaaagg gatatgcccc tgatcgtggt acatagccac taccatatcg
     3181 aatagccctt catggcattg cataaacacg gtatctggcg ggcacgggcc agtaacatca
     3241 atatcttcgg cctgcattgc ttcaatcgca ggcgcgataa tctcgatttc ctcagtgccg
     3301 aataaaccat gttcccctgc atgtggattt acacccgcca cggcaatacg cggacgctca
     3361 ataccaacac gtttcaggaa gtggttcgca actcgaataa ccgttttgac cctttcacca
     3421 ttcaaagtat ccaggaattt acgcagtgag atgtgagtcg aaatatggat aaccttgagc
     3481 ttctcggtat agagcaccat cgcgtactct ttgctgccgg taagatgggc cagcaattcc
     3541 gtatgccccg gatagttatg cccgccaaga tgcagcgctt ctttattcag cggcgcagtg
     3601 gctatggctt tcacctcgcc tgataaggcc agagccgttg cacgtttgat acagcgatac
     3661 gctaaatcgc ctgccacagc ctgtaccact ccgggtgtca gcgcatcggg gttagccagc
     3721 ggctcatcca tcacgttaat cacgccggga gcaaaatggg cgtcgcacac cttttgaatg
     3781 acgcgtaact ctgcctgcgg cgtgatattc atcgccataa tacgtcgcag cgtgcgcaca
     3841 cagcccacca ccaccaccgg ggcaccagca agcccggctt cgctcaggga tttaataatg
     3901 atctccgggc caatacccgc cggatcgccc atcgttaccg caataatatt attcactacg
     3961 cttctcctcg ataaaattca gaacctgatg caacgtggtc tcatcgccaa acccaccggc
     4021 tttcgtcatc accgaacggg accagacgcc gcccagaaag tgaccgtatg gaacgcattg
     4081 cgccaccttc cccgtaatac gaaatccggt cgcgcctaac gcactggctg ttgccattgc
     4141 gacatcacca ccagagagat aaagcgcatc gggcattgcg caaagcagaa cttgccgggt
     4201 aagttcgcca agaaaccggc aaattttttc cccaagtgca gcgcgactca tctgccaacg
     4261 ctggcaaagg gtgtcgatct gatgccttgc tacagaatcg ttacaggtgt ggacaataca
     4321 gtggtcgcct ttctgcaagg cctgcacaat acgcgcgtca tagtcactgg cattgcctgc
     4381 cagaatgtgt tcaacatcga cgtatatctg tgtgatacgt gggtgtgaat gaagtgtggc
     4441 gatctgccgt tgagcgattt cgctcattga accaataatg gccagcacgg tgggtggcgg
     4501 cataatcgcg gagcgccggg caacggcatc acaaatacca gcggagccga ccagcagcag
     4561 cggttgttta gcctgcatca cagcggcagc gatgcgatcc aggtcgctgt ccgtctgcgc
     4621 atctatcacg ccaatccacg gttgctcata agacaaatgg ctgagctgag aaaccgtaac
     4681 gggctggcat ggaatggccg tctgcaaccg gatgatgtcc gcaattcggg cgctcaatac
     4741 cggggttttc ggatcgctag caaactcggt ttccgttatc cgcacaccgt ttacccaaca
     4801 ctcaccggcc actgtggtcc ttcccgcctg aggaaatgcg ggggcaacca ctgcgcccgt
     4861 tataccgcat gccttcatca gggcttcaat ttctgcgccg atattgcctc gcagcgtgga
     4921 atctatcttt ttaatcacga gcggcgggtt attcgccaga gggagatgac tcatcagcga
     4981 ggttattttc atcgccgcca gcttaggatc catcgcccga ctgtcgctgt taatcaccca
     5041 tacgctggca tcaccgcgat aaggcatttc aaaggccaca tcaactgtat gccccacctg
     5101 cgccaggctt acccccgcgt cgttggctcc cgtgaaatca tcggcaacga tgagaatgct
     5161 cggcttagtg attccctttt ccatcatcac tccaggttgt tttatgataa caatgattat
     5221 attcaatcat gattgattaa atgtgagcaa gctcaagtta ttaatcactc gaataaatta
     5281 taaaattaga ccatgttacg taggctacgg cattttgaat gattgaattc aatcaccaga
     5341 agagaggtta tttgtggtaa ttatcaatag cacgatactg agcggcgcag gcgctatccc
     5401 ttccctgacg tcgctcttac ccgacatcag aaaaatgctg ctggtcactg accgtaatat
     5461 tgcgcagctc gacggtgtgc agcagattcg cgccttactg gaaaagcact gcccgcaggt
     5521 taacgttatc gataatgtgc ccgcagagcc cacgcatcat gatgtgcgcc agctaatgga
     5581 tgcccttggc gatgcctctt ttgatgtggt ggtcgggatc ggcggtggca gcgtgttgga
     5641 tgtggcgaag ctgctatcgg tgctttgcca tccacaatca ccggggctgg atgcgctgct
     5701 tgcgggtgaa aaaccgactc agcgggtgca atcatggttg attcctacaa ccgccggaac
     5761 cggctcagaa gccacgccga atgcgattct ggcaatccct gagcaaagca cgaaggtggg
     5821 tattatttcc caggtgctgt taccagacta tgtggcgctt ttcccggaac tgaccaccag
     5881 tatgcccgcg catattgcgg cgtccacggg cattgatgct ctttgccact tactggagtg
     5941 ttttaccgcg accgtggcaa atccggtcag cgataacgcg gcgctgactg ggttaagtaa
     6001 acttttccgg cacattcaac ccgccgtgaa cgatcctcag gatctgcgcg caaaactgga
     6061 aatgctgtgg gcgtcttact atggcggcgt agcgataacc catgcgggca cgcatctcgt
     6121 tcatgcgctc tcctacccgt taggtggcaa atatcatctg ccgcatggcg tcgcgaatgc
     6181 catcttgctg gcgccgtgca tggcgtttgt tcgcccctgg gcggtcgaga aatttgccca
     6241 ggtctgggat tgcattcccg atgcggaaac cgccctgagc gcggaagaaa aatctcatgc
     6301 cctggtgacc tggttacagg cattagtcaa tcaactcaag ctacccaaca atctcgcgga
     6361 tctcggcgta ccgccagagg atattgcctc tctgagcgag gcggcactga acgtgaagcg
     6421 ccttatgaac aatgtgccgt gccagcttga tctacaggac gtacaggcca tttaccaaac
     6481 actgtttccg caacatcaat ttaaggaata aatcatgccg aaaaccattg aaggtgtatt
     6541 aaccgctatc gtcaccccgt ttaccgcgac cggcagtctg aatatcccgg cgttaaaagt
     6601 gcaggtgaat cgtcaactgg aagcgggtaa cgcgattttt tgcggcggca ccaacggcga
     6661 gttttttgtg ttgaatgaac aggagaagct cagcgttacg caaacctgcg tggatgaagt
     6721 ggctggtcgt gcgccagtcg tggcacacat tggcgagatc tctacgcgcg aaacgattcg
     6781 tctgggtcag cagattgaaa aacttggcgt agatgccgtg tcggtcattg ccccttactt
     6841 cgtaccgctg aaacaggaag agttgattgc gcattacagc gcaattgccg acacactgag
     6901 cattccgatg tttctctata acatcccggc ccgcactggc aatacgatcc agccagaaac
     6961 cgcgcgtgct ctggcgtcgc accccaatat cattgggatt aaagacagcg acggaagcga
     7021 cgaaagcctg aagggttttc tcgatgcggt gcgcgacatt gacggcttta atgtgctcaa
     7081 cggcccggat tcgctgatcc ataaagggtt tgtcgaggga tgttcagcct gtatctctgg
     7141 gctcgccaac gtcgcgccgc gagaaatcaa tgccatctgg tctcgcttcc atgccggtga
     7201 tattgaaggg tcttatgaag cacaggagag tgtaacgggc ctgcgtaccg atctttataa
     7261 agtagcattc tccccggctg cggtgaaaaa agcgttgcag cttatggggc atgatgttgg
     7321 tgatagccgc tacgcggtta atttcacgcc tgaacagatc agcgagattc aacaaattat
     7381 tcgtcattat aacattaatt aaattaactc tattatccag cccgctataa agtttagata
     7441 aagagaataa aggattaccc catgtttttg tggtttatgc agccagatat ctggctcact
     7501 ttaattaccc tcacctttct ggaaattatt cttggggtgg ataatattat ttttctttca
     7561 ctggtggtgg caaaacttcc gttatcacaa caaaatatgg cgcgtaaact gggtttaagc
     7621 tgcgcgatga ttatgcggat attattgctg atatccattg cgtggctttc acatattacc
     7681 cagccgcttt ttaccgtgct gacgctggag atttcgttcc gcacgttgat tctgctcggg
     7741 ggcgggctgt tcctgattta taaagcgata caggagatac gcgaagagct gtcgcccgcg
     7801 caggaagacg aacatggcag cggatcgcgg caactgtcgt tgtgcggtgc cattgtacag
     7861 ataatgctgc tcgatatcgt gtttagcctg gattcggtga tcaccgccgt cggcctttct
     7921 cagcatatat ttatcatgat tgccgccgta atgattgccg tcggtgtcat gatgtttgcg
     7981 gcgaaaacaa ttggtgattt cgttaacgcc acgccgtcaa taaaaatact ggcgttaacc
     8041 tttttattgt ttgtcggtgt attgctggtt gccgatagtc tcaacattca tattgccaaa
     8101 gagtatctct acttcgcgat atttttctca ttaagtgttg agacactcaa tattatccgt
     8161 gaaagaaaaa ataaaaaagt ttcgacattg atcgaaacgc atgaatcgca ctcgcattaa
     8221 taaatctatt accaacttta agatggagtc taactatgtc tgtagccctt attcgtgacg
     8281 gcgtcatccg tccatccgaa aacgattcgc atgtgcttac cgccatgctg ccctcgtcct
     8341 gcccgcaaaa ccacgcggcg aatattctgc ctttgccgga tggcgcgtta atgtgcgtct
     8401 ggtttgcggg aacgcaggaa ggtattgccg atatttctgt ctggggatcg cgattgcccg
     8461 ctggcggaat gcagtggagc gatgcggcca aactttccca cgatgacacg cgttcagagc
     8521 aaaacccggt gctgtttctc gcgccggata acgtgctgtg gctcctatgg accgcacaaa
     8581 tatccggtaa tcaggacacc gccatcgtcc gctaccgtaa gtcagacgac ctcggacaaa
     8641 cctggggcga gattgccacc ctgcttgata aacccggtac gttcattcga cagccaatca
     8701 cggtgcttga taacggcaac tggctgctgc ccgtctttta ttgccgtacc caacccggcg
     8761 aaaaatgggt cggcaatgat gatatcagcg cagtgaaaat ttccgctgac ggtggtcact
     8821 cctggcgcga tgtcgaggtg ccgcaaagtc tcggctgtgt tcatatgaat atcacaatgt
     8881 tgcacgacgg tacgttggtt gctctctttc gcagccgttg ggcagacaac atctatatca
     8941 gccattcagt ggacaacggc gagagttggt cggtgctgca agcaaccgaa ttgcccaaca
     9001 acaattcgtc tattcaggta acgacgcttg ccagcggcga actggcgctg gtgtacaacg
     9061 cgatgagtgc ggcaggcgca gtagaacgtc gcgcgtcgct ttatgacgaa atcgacgatg
     9121 gcgacgacag ccgcaaagaa ccgacagccg tcggacgctc cgctttctgg ggtgccccac
     9181 gcgcgccgat gacggtagcg atttctgccg atggtgggaa aagctggtcg tggcggcgca
     9241 atctcgatga aggcgacggc tactgcatga ccaacaattc cctggaaaag ctaaatcgtg
     9301 agttctccta ccccagcatc aaacaaagcc cggacggtac gctacatatc gcttacacct
     9361 ggtggcgtca ggccatcaag tacgtacgca tctcccccga gtgggttaag gggcaggcat
     9421 catgattatc ggtaatctca accatttgtc gctggcgggg cttcctgcct gggtgagaaa
     9481 tattctgctg cgcccggagt gttcgttatc ggcgttatcc accagagagg acggtcgctg
     9541 gcaacctgaa ggatgtcggt ggttctgctc gctgggaact tcagacacgc aacccgccga
     9601 acttcgccat acggagtatc accatctatg ggccgatata caggtggtga ttactggttg
     9661 tgagggcatt aatgcgggaa cgcggcccat cgctcgcgaa aacgatgaag aacgtaagcc
     9721 cgatctgttt atcgccccat cccctgaaaa cagtgtcgcc atcaccctac acgccggtga
     9781 tttcgccgtc tttatgcctg aggaacctca ccaggcactg tgcgcaattg gcacggctac
     9841 ttcaatacgc aaagcggtct ttaaagtacc gcgcgacatg ctggaagcct aaaaggagag
     9901 aaaaaatgac aatggaaatg atcctggcat taggaatact ggtcctgatg atcgtgctga
     9961 tcatgtcgga caaaatgcct tttggcgcac cgccactgct tgcgtgttta ttgctggttg
    10021 tatcgggact ttcgaccgtt caacaggctt ttgccggatt cgtcaatcca agcgtggtga
    10081 tgattgcagg gtttatggtg gtcatggcgg cgctacaaaa aacccggctt atcagcaacg
    10141 ttaaatctgc gatgataagc ctggtcaata aaggcagtta ccgcagctat gggctgttat
    10201 tagtcattgt tatgctgggt gccagtcttg ccggcaccgg agcgaccggt tattacgtgc
    10261 taattctgtc gctggtatcc accattccgt acagtaaaaa gctaccaaca tcgaaattaa
    10321 tgatgcccct gggatttgcc accaaccacc cgcttcttcc tatcaatctc gcgcttctct
    10381 ttggcgttac ggcgaccgta ctcgaaaccg cggggtttca tcaggcgatt tcgatggggc
    10441 gctttgcgct ggtgaatctc atcatgtcag cggctttcct cgcatggagt cttattgcct
    10501 accgttttct tccggatcat cccattgcgg atgcttccga ggatgcgctg gcggcacgcg
    10561 aggaaacgtt taacgccctt cctgcctgga aagaatattg cactattgcc gcattcgctg
    10621 tcagcgttat cggcatgatg ctaatgaaca ttctgggaaa tatcgccttc gttattccgg
    10681 gtcttgcggg tgcgtttgtt ctgatgatcg atgtactgga cttcaaagaa gttcgcgatc
    10741 atatgggggc tccggtcatt ttaatgatgg cgggggtgat cggtgtagct gatgcactgg
    10801 cgggcaccgg ctttacggcg atggttggcg atgccgttgc aggtgtgctc ggttctggcg
    10861 tctcaccgtt tgtatttatt gtcgcctttg ctttgcttac cagtacctgc gccaccttca
    10921 cgggttcgaa tatggggtca gtatatattt ttgcccccat cgccattgcc gcctgtacta
    10981 gccttgggct taacccgacc gctgccgcga ttgcggtggt gatttctggc tggaatggcg
    11041 gctatatgcc tattgacgga atgccagcca tgatcctcgg aatggggaaa tacaaacttc
    11101 ccgaattctg ggtgttctct gtaccaatgt atctcatccg cattctggcg ctttgtgcag
    11161 gcgctgtttt tatcttccca atgtaatctc agacaaaaaa agcggcagag aagatccctg
    11221 ccgcttttta ttgttggatg cgacgctgcc gcgtcgcatc agacataaag cagattactt
    11281 tttgatttca tacagcggtg tttgacccgc cacaacatgg ccctgagctt taatgataag
    11341 gccgctgaaa tcatcgatat tgctgcaaac caccgggcta atcatcgaac gggcgttagc
    11401 gttcaggtaa tccagatcca tttccagaat cggttgccct gcgcttacct gcgcgccctc
    11461 ttccaccaga cgtttaaagc ctttaccttc cagcgctacg gtgtcgatac ccatatggac
    11521 gacgatctcc gcgccttttt cggtttccag acagaacgcg tggttggtgt tgaagatttt
    11581 cacgattgtt cctgcggctg gtgatacgac gattttatct gtcggtttca ccgccacacc
    11641 gtcacccacc gctttgctgg cgaatgcttc gtcaggaatc tgatccagtg ccacaacatc
    11701 cccggtaatc ggcgatacca gctccgcgat agataccgcg tttggtacag cctgcggttt
    11761 tgctacagga gcggcagttg ccggagttgc ttcagctgac gcagcggcta ccggaccacg
    11821 ggcaacgact ttcttcatcg catcgccgat ggattctgct ttcgcgccaa caatcacctg
    11881 aatagtctgt ttgttcagtt ttactacccc agaagcaccc agacgtttac acatcgcatc
    11941 gttgacgcga gctgagtcaa ccacggtaag gcgcagacga gtaatacagg cgtcaatggc
    12001 tttcaggttg tcagtaccgc caaccgcagc aatatagttg gttgccagtt gattgagacc
    12061 ttcttcagta ttgctgttag cctcttcagt aacgatctcg tcttctttat cttcacgacc
    12121 cggcgttttc aggttgaaca tgcggataac caaactgaac accacgaagt agatagcgaa
    12181 gaagacaacc cccatcacca gcagcatcca gacgttctgg ctggcggccg gcaggttata
    12241 catcaacgcg tagtcgatag cccccgcaga gaaagagaag ccggcatgga tacccagcaa
    12301 cgttgccaca aacaggctga taccggtcag cagtgcgtgc aggaggtaca gcagcggtgc
    12361 aaggaacatg aacaggaatt ccagcggctc agtcacaccg gtcaggaacg cagtaacagc
    12421 aacagaaagc agcatcccgc caaccatcgg acgacgctct ttcggtgctg cgaagtacat
    12481 cgccagcgcc gcacccggca ggccgaacat cataatcggg aagaagccgg acatgaacat
    12541 ccccgcggtg ccgtcaccgg catagaagcg gttgatatca ccgtggaaaa ccgttcccgc
    12601 cgcgttggtg aattcaccaa tctggaacca ggcgatggtg ttcagcacct gatgcagacc
    12661 ggttgggatc agcagacggt tgatgaaacc aaagataccg gaacccagcg cgcccgcaga
    12721 aacgatccac tcgccgcctg catggatagc gtgctgtacc ggtggccaga cgtaaccaaa
    12781 aatggccgcc agcaccagac agaagaagcc ggtggctatc ggcacaaagc gtttgccgcc
    12841 gaagaagctc aggaagtccg gcagtttaat atcggaccaa cggttatagg ctgcgccacc
    12901 aaccagaccg gtaatgatac ccgccagtac acccatgtta atttctgggt tgatggtcac
    12961 catcgctttg gttaacacaa agtaacctac cgcacccgcc agtgccgccg cacctgcgct
    13021 gtctttcgac cagctggatg ccacgccgat ggcgaatatt aatgcgaggt tatcaaaaat
    13081 cgcaccgccc gcctgggcaa taaacgcaac gttaagtaaa tctggctgac cgaatcgcag
    13141 caacagcgcc gccaccggca gcaccgcgat agggagctgt aacgccctac cgagtcgctg
    13201 gaaaaaacct aaaatattca tcttattccc cctacgagaa ccctatttgg ctcgtttaaa
    13261 gccgtatttt tattttgctg caaattgtac tgccgatgtt ctgtaatcag attgttagat
    13321 catctgctac agagtgtgtg aaaatttaat tcgtatcgca aattaaacgc gtgtcttttg
    13381 tgagttttgt caccaaatat cgttatcatc actccctttt actggctaaa ccagaaaact
    13441 tattttatca ttcaaaaaat caggtcggat tgacgcctgt ctgcgcaaat ccaggttacg
    13501 cttaaagatg cctaatccgc caacggctta cattttactt attgaggtga ataatgagac
    13561 tgatccccct gactaccgct gaacaggtcg gcaaatgggc tgctcgccat atcgtcaatc
    13621 gtatcaatgc gttcaaaccg actgccgatc gtccgtttgt actgggcctg ccgactggcg
    13681 gcacgccgat gaccacctat aaagcgttag tcgaaatgca taaagcaggc caggtcagct
    13741 ttaagcacgt tgtcaccttc aacatggacg aatatgtcgg tctgccgaaa gagcatccgg
    13801 aaagctacta cagctttatg caccgtaatt tcttcgatca cgttgatatt ccagcagaaa
    13861 atatcaacct tctcaacggc aacgccccgg atatcgacgc cgaatgccgc cagtatgaag
    13921 aaaaaatccg ttcttacgga aaaattcatc tgtttatggg cggtgtaggt aacgacggtc
    13981 atattgcatt taacgaaccg gcgtcttctc tggcttctcg tactcgtatc aaaaccctga
    14041 ctcatgacac tcgcgtcgcg aactctcgtt tctttgataa cgatgttaat caggtgccaa
    14101 aatatgccct gactgtcggt gttggtacat tgctggatgc cgaagaagtg atgattctgg
    14161 tgctgggtag tcagaaagca ctggcactgc aggccgccgt tgaaggttgc gtgaaccaca
    14221 tgtggaccat cagttgtctg caactgcatc caaaagcgat catggtgtgc gatgaacctt
    14281 ccaccatgga gctgaaagtt aagactttaa gatatttcaa tgaattagaa gcagaaaata
    14341 tcaagggtct gtaattgtta tccctgccct ggctccttgc tcagggcaat attttttaaa
    14401 atcgggggtc agaatgtatg cattaaccca gggccggatc tttaccggcc acgaatttct
    14461 tgatgaccac gcggttgtta tcgctgatgg cctgattaaa agcgtctgtc cggtagcgga
    14521 actgccgcca gagatcgaac aacgttcact gaacggggcc attctctccc ccggttttat
    14581 cgatgtgcag ttaaacggct gcggcggcgt acagtttaac gacaccgctg aagcggtcag
    14641 cgtggaaacg ctggaaatca tgcagaaagc caatgagaaa tcaggctgta ctaactatct
    14701 gccgacgctt atcaccacca gcgatgagct gatgaaacag ggcgtgcgcg ttatgcgcga
    14761 gtacctggca aaacatccga accaggcgtt aggtctgcat ctggaaggtc cgtggctgaa
    14821 tctggtaaaa aaaggcaccc ataatccgaa ttttgtgcgt aagcctgatg ccgcgctggt
    14881 cgatttcctg tgtgagaacg ccgacgtgat taccaaagtg actctggcac cggaaatggt
    14941 tccagcggaa gtcatcagca aactggcaaa tgccgggatt gtggtttctg ctggtcactc
    15001 caacgcgacg ttgaaagaag cgaaagccgg tttccgcgcg gggattacct ttgccaccca
    15061 tctgtacaac gcgatgccgt atattaccgg tcgtgaaccg ggcctggcgg gcgcgatcct
    15121 cgacgaagct gacatttatt gcggtattat cgctgatggc ctgcatgttg attacgccaa
    15181 cattcgtaac gctaaacgtc tgaaaggcga caaattgtgt ctggttaccg atgccaccgc
    15241 gccagcaggt gccaacattg aacagttcat ttttgcgggt aaaacaatat actaccgtaa
    15301 cggactttgt gtggatgaga acggtacgtt aagcggttca tccttaacca tgattgaagg
    15361 cgtgcgtaat ctggtcgaac attgtggtat cgcactggat gaagtgctgc gtatggcgac
    15421 gctctatccg gcacgtgcga ttggcgttga gaaacgtctc ggcacgctcg ccgcaggtaa
    15481 agtagccaac ctgactgcat tcacacctga ttttaaaatc accaggacca tcgttaacgg
    15541 taacgaggtc gtaactcaat aagagaaagt atgacaccag gcggacaagc tcagataggt
    15601 aatgttgatc tcgtaaaaca gcttaacagc gcggcggttt atcgcctgat tgaccagtac
    15661 gggccaatct cgcggattca gattgccgag caaagtcagc ttgcccccgc cagcgtaacc
    15721 aaaattacgc gtcagcttat cgaacgcggg ctgatcaaag aagttgatca gcaggcctcc
    15781 accgggggcc gccgcgctat ctccatcgtc accgaaaccc gcaatttcca cgcaatcggc
    15841 gtacggcttg gtcgtcacga cgccaccatc accttgtttg atctcagcag caaagtgctg
    15901 gcagaagaac attacccgct gccggaacgt acccagcaga cgctggaaca tgccctgctg
    15961 aatgccattg ctcagtttat tgatagctac cagcgcaagc tacgcgagct gatcgcgatt
    16021 tcggtgatcc tgccagggct tgtagacccg gacagcggca aaattcatta catgccgcat
    16081 attcaggtag aaaactgggg gctggttgaa gcactggaag agcgttttaa agtgacctgt
    16141 tttgtcggcc acgatatccg cagtctggcg ctggcagagc actacttcgg tgcaagtcag
    16201 gattgcgaag actccattct ggtgcgtgtc catcgcggaa ccggggccgg gattatctct
    16261 aacgggcgaa tttttatcgg gcgcaacggc aacgtcggtg aaattggcca tattcaggtc
    16321 gaaccgctgg gtgaacgctg ccactgcggc aactttggct gcctggaaac tatcgccgcc
    16381 aatgctgcca ttgaacaacg ggtgttgaat ctgttaaagc agggctacca gagccgtgtg
    16441 ccactggacg actgcaccat caaaactatc tgcaaagccg cgaacaaagg cgatagcctg
    16501 gcctcggaag tgattgaata tgtcggtcgt catctgggta aaaccatcgc cattgctatc
    16561 aacttattta atccgcaaaa aattgttatt gctggagaaa tcaccgaagc cgataaagtg
    16621 ctgctccctg ctattgaaag ctgcattaat acccaggcgc tgaaggcgtt tcgtactaat
    16681 ctaccggtgg tacgttctga gttggatcac cgctcggcaa tcggcgcttt tgcgctggta
    16741 aaacgcgcca tgctcaacgg tattttgctc cagcatttgc tggaaaatta atgtgctttt
    16801 atagtggcgc ttattgttgt caatattctg ggtagtccat gaccattaaa aatgtaattt
    16861 gcgatatcga cggcgtgctg atgcacgata acgtcgccgt accgggtgca gcggaatttt
    16921 tgcacgggat tatggataaa ggcctgccgc tggtgttgct gaccaactat ccttcgcaga
    16981 ccgggcaaga tctggcgaat cgctttgcca ctgccggtgt cgatgtaccg gatagcgtgt
    17041 tttatacctc cgcaatggcg accgccgatt ttctgcgtcg ccaggaaggc aagaaagcgt
    17101 atgtggtggg cgaaggcgca ctgattcatg aactgtacaa agccggtttc actattaccg
    17161 atgtgaaccc tgattttgtg attgttggcg aaacgcgttc ctacaactgg gacatgatgc
    17221 ataaagcagc ctatttcgtc gctaacggtg cacgctttat cgccaccaac ccggacaccc
    17281 acgggcgcgg tttttatccc gcctgtggcg cgttgtgtgc agggatcgag aaaatctccg
    17341 ggcgcaaacc gttctatgtt ggaaagccga gtccgtggat catccgcgcg gcattaaaca
    17401 aaatgcaggc gcattcggaa gaaacggtga ttgtcggcga taacttgcgt accgatattc
    17461 tggcgggctt ccaggccggt ctggagacga ttctggtgct ttctggtgtt tcgtcgctcg
    17521 acgatatcga cagtatgccg ttccgcccaa gttggattta cccatcggtc gctgaaatcg
    17581 acgttatctg aatagcaacc acgcctcagg gcgtggtttc ttatttttac ccatcattaa
    17641 aatcacccca ttcaataaaa cccgtcaaaa actatcgatc catcaataaa tatacccaaa
    17701 agccctcccc tttttcatca atcagcaatc gccattacgt tttttatttt tccactgcca
    17761 aatcgcttgc gcaccgtgct gctttgcggc atttttttaa caagtaaaca caacacgcag
    17821 taaacaccag gttaatggag aaggttatgt gttcaatttt tggcgtattc gatatcaaaa
    17881 cagacgcagt tgagctgcgt aagaaagcac tcgagctgtc acgcctgatg cgtcatcgtg
    17941 gcccggactg gtccggtatt tatgccagcg ataacgccat tctcgcccac gaacgtctgt
    18001 caattgttga cgttaacgcg ggggcgcaac ctctctacaa ccaacaaaaa actcatgtgc
    18061 tggcagtaaa cggtgaaatc tacaaccacc aggcattgcg cgctgaatat ggcgatcgtt
    18121 accagttcca gaccgggtct gactgtgaag tgatcctcgc gctgtatcag gaaaaagggc
    18181 cggaatttct cgacgacttg cagggcatgt ttgcctttgc cctgtacgac agcgaaaaag
    18241 atgcatatct gattggtcgc gaccatctgg ggatcatccc actgtatatg ggctatgacg
    18301 aacacggtca gctgtatgtg gcctcagaaa tgaaagccct cgtgccagtt tgccgcacga
    18361 ttaaagagtt tccggcgggg agctatttgt ggagtcagga cggcgaaatc cgttcttatt
    18421 atcatcgcga ctggttcgac tacgatgcgg tgaaagataa cgtgaccgac aaaaacgagc
    18481 tgcgtcaggc actggaagat tccgttaaaa gccatctgat gtctgatgtg ccttacggtg
    18541 tgctgctttc tggtggtctg gattcctcaa ttatttccgc tatcaccaag aaatacgccg
    18601 cccgtcgcgt ggaagatcag gaacgctctg aagcctggtg gccgcagttg cactcctttg
    18661 ctgtaggtct gccgggttca ccggatctga aagcagccca ggaagtggca aaccatctgg
    18721 gcacggtgca tcacgaaatt cacttcactg tacaggaagg tctggatgcc atccgcgacg
    18781 tgatttacca catcgaaact tatgatgtga ccactattcg cgcttcaaca ccgatgtatt
    18841 taatgtcgcg taagatcaag gcgatgggca ttaaaatggt gctgtccggt gaaggttctg
    18901 acgaagtgtt tggcggttat ctctacttcc acaaagcgcc gaacgctaaa gagttgcatg
    18961 aagagacggt gcgtaaactg ctggccctgc atatgtatga ctgcgcgcgt gccaacaaag
    19021 cgatgtcagc ctggggcgtg gaagcacgcg ttccgttcct cgacaaaaaa ttccttgatg
    19081 tggcgatgcg cattaaccca caggataaaa tgtgcggtaa cggcaaaatg gaaaaacaca
    19141 tcctgcgtga atgttttgaa gcgtatctgc ctgcaagcgt ggcctggcgg caaaaagagc
    19201 agttctccga tggcgtcggt tacagttgga tcgacaccct gaaagaagtg gcagcgcagc
    19261 aggtttctga tcaacagctg gaaactgccc gcttccgctt cccgtacaac acgccgacct
    19321 caaaagaagc gtatctgtac cgggagatct ttgaagaatt gttcccgctt ccgagcgccg
    19381 ctgagtgcgt gccgggcggt ccttccgtcg cttgttcttc cgctaaagcg attgagtggg
    19441 atgaagcgtt caagaaaatg gacgatccgt ctggtcgcgc ggttggcgtt caccagtcgg
    19501 catataaata agacgtgtaa tattgccccg gagaaatccg gggcaatttc agttactggg
    19561 gcgcttgttg attctgatat gcagtaagga aatgttccgg gtttgccaca tcgctatttg
    19621 acaactcatc actgtaggcc accaaccagg tcgcctgctc atccggaata tgcagtctgc
    19681 catttccctc tttcaggcgt aataactcaa aagatttgcc cttaattacg gcggtatagg
    19741 atttctcacc ttcctgtaat gctttcactt tacagcgaaa tatctgacca tcgatgtcat
    19801 tatcaacatg cgatacctga atgagggctt cattagaagc tttcgggcct atccgcatca
    19861 tccacaccac agcgccttcc tgcccacgat agccaaaaac atatttaccg atttccggtt
    19921 taaccgtatc ggcgaacgca gattgcataa gtaataacgc acccatcaac gccgtcataa
    19981 aacgcagcat agtattccct caataaatcg cctgaagtgg tagcagagat gcaggcgtag
    20041 cgatccctgc cctgtcctgt tgcaacgggc cagtatttca tagattaatt tcccaccact
    20101 attgttgaat tccgaatttc atcctgtatg acaaaagaat ggctgtaggg tggggaaaaa
    20161 acacaaagta aacaataatt gacgaatata gcgccatgct gttcgcaacc taaccaaaca
    20221 gtcactttcg agcaattttc cttgaaaaag aggttgacgc tgcaaggctc tatacgcata
    20281 atgcgccccg caacgccgat aaggtatcgc gaaaaaaaaa gatggctacg tagctcagtt
    20341 ggttagagca catcactcat aatgatgggg tcacaggttc gaatcccgtc gtagccacca
    20401 tctttttttt gcgggagtgg cgaaattggt agacgcacca gatttaggtt ctggcgccgc
    20461 aaggtgtgcg agttcaagtc tcgcctcccg caccattcac cagaaagcgt tgtacggatg
    20521 gggtatcgcc aagcggtaag gcaccggttt ttgataccgg cattccctgg ttcgaatcca
    20581 ggtac
//
LOCUS       DAFGPF010000086        20150 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFGPF010000086 DAFGPF010000000
VERSION     DAFGPF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20150
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.086"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            3..1439
                     /gene="gspA"
                     /locus_tag="LSX49_003529"
     CDS             3..1439
                     /gene="gspA"
                     /locus_tag="LSX49_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001340787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspA"
                     /protein_id="HBL7169891.1"
                     /translation="MREKHQTWRLCYLLGEAGSGKTRLAQQLQKDKHRRVITLSLVVS
                     WQGKAAWIVTDDNAAEQGCRDSAWTRDEMAGQLLHALHRTDSRCPLIIIENAHLNHRR
                     ILDDLQRAISLIPDGQFLLIGRPDRKVERDFKKQGIELVSTGRLTEHELKASILEGQN
                     IDQPDLLLTARVLKRIALLCRGDRRKLALAGETISLLQQAEQTCVFTAKQWRMIYRVL
                     GDNRPRKMQLAVVMSGTIIALTCGWLLLPSFTAPLPVPAWLIPVTPVVKQDMTKDIAH
                     VVMRDSEALSVLYGVWGYEVPADSAWCDQAVRAGLVCKSGNASLQTLVDQNLPWIASL
                     KVGDKKLPVVVVRVGDATVDVLVGQQTWTLTHKWFELVWTGDYLLLWKMSPEGESTIT
                     RDSSEEEILWLETMLNRALHISTESSAEWRPLLVEKIKQFQKSHHLKTDGVVGFSTLV
                     HLWQVAGESAYLYRDEANISPETTVKGK"
     gene            1441..1860
                     /gene="gspB"
                     /locus_tag="LSX49_003530"
     CDS             1441..1860
                     /gene="gspB"
                     /locus_tag="LSX49_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative general secretion pathway protein GspB"
                     /protein_id="HBL7169892.1"
                     /translation="MFEFYIAAREQKETGHPGIFSRQKHSTIIYVICLLLICLWFAGM
                     VLVGGYARQLWALWIVKAEVTVDAETPAFKQSTQHYFFKKQPLPVVESVEEEDDPGVA
                     VENAPSSSEDEDNTVEESDEKAGLRERVKNALNELER"
     gene            2098..2409
                     /gene="rpsJ"
                     /locus_tag="LSX49_003531"
     CDS             2098..2409
                     /gene="rpsJ"
                     /locus_tag="LSX49_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBL7169893.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            2442..3071
                     /gene="rplC"
                     /locus_tag="LSX49_003532"
     CDS             2442..3071
                     /gene="rplC"
                     /locus_tag="LSX49_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBL7169894.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            3082..3687
                     /gene="rplD"
                     /locus_tag="LSX49_003533"
     CDS             3082..3687
                     /gene="rplD"
                     /locus_tag="LSX49_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBL7169895.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            3684..3986
                     /gene="rplW"
                     /locus_tag="LSX49_003534"
     CDS             3684..3986
                     /gene="rplW"
                     /locus_tag="LSX49_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBL7169896.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            4004..4825
                     /gene="rplB"
                     /locus_tag="LSX49_003535"
     CDS             4004..4825
                     /gene="rplB"
                     /locus_tag="LSX49_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBL7169897.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            4842..5120
                     /gene="rpsS"
                     /locus_tag="LSX49_003536"
     CDS             4842..5120
                     /gene="rpsS"
                     /locus_tag="LSX49_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBL7169898.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            5135..5467
                     /gene="rplV"
                     /locus_tag="LSX49_003537"
     CDS             5135..5467
                     /gene="rplV"
                     /locus_tag="LSX49_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBL7169899.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            5485..6186
                     /gene="rpsC"
                     /locus_tag="LSX49_003538"
     CDS             5485..6186
                     /gene="rpsC"
                     /locus_tag="LSX49_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBL7169900.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            6199..6609
                     /gene="rplP"
                     /locus_tag="LSX49_003539"
     CDS             6199..6609
                     /gene="rplP"
                     /locus_tag="LSX49_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBL7169901.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            6609..6800
                     /gene="rpmC"
                     /locus_tag="LSX49_003540"
     CDS             6609..6800
                     /gene="rpmC"
                     /locus_tag="LSX49_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBL7169902.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            6800..7054
                     /gene="rpsQ"
                     /locus_tag="LSX49_003541"
     CDS             6800..7054
                     /gene="rpsQ"
                     /locus_tag="LSX49_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBL7169903.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            7219..7590
                     /gene="rplN"
                     /locus_tag="LSX49_003542"
     CDS             7219..7590
                     /gene="rplN"
                     /locus_tag="LSX49_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBL7169904.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            7601..7915
                     /gene="rplX"
                     /locus_tag="LSX49_003543"
     CDS             7601..7915
                     /gene="rplX"
                     /locus_tag="LSX49_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBL7169905.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNATTGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            7930..8469
                     /gene="rplE"
                     /locus_tag="LSX49_003544"
     CDS             7930..8469
                     /gene="rplE"
                     /locus_tag="LSX49_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBL7169906.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            8484..8789
                     /gene="rpsN"
                     /locus_tag="LSX49_003545"
     CDS             8484..8789
                     /gene="rpsN"
                     /locus_tag="LSX49_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL7169907.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            8823..9215
                     /gene="rpsH"
                     /locus_tag="LSX49_003546"
     CDS             8823..9215
                     /gene="rpsH"
                     /locus_tag="LSX49_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBL7169908.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            9228..9761
                     /gene="rplF"
                     /locus_tag="LSX49_003547"
     CDS             9228..9761
                     /gene="rplF"
                     /locus_tag="LSX49_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBL7169909.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            9771..10124
                     /gene="rplR"
                     /locus_tag="LSX49_003548"
     CDS             9771..10124
                     /gene="rplR"
                     /locus_tag="LSX49_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBL7169910.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            10139..10642
                     /gene="rpsE"
                     /locus_tag="LSX49_003549"
     CDS             10139..10642
                     /gene="rpsE"
                     /locus_tag="LSX49_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBL7169911.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            10646..10825
                     /gene="rpmD"
                     /locus_tag="LSX49_003550"
     CDS             10646..10825
                     /gene="rpmD"
                     /locus_tag="LSX49_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBL7169912.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            10829..11263
                     /gene="rplO"
                     /locus_tag="LSX49_003551"
     CDS             10829..11263
                     /gene="rplO"
                     /locus_tag="LSX49_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBL7169913.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            11271..12602
                     /gene="secY"
                     /locus_tag="LSX49_003552"
     CDS             11271..12602
                     /gene="secY"
                     /locus_tag="LSX49_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBL7169914.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            12634..12750
                     /gene="rpmJ"
                     /locus_tag="LSX49_003553"
     CDS             12634..12750
                     /gene="rpmJ"
                     /locus_tag="LSX49_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBL7169915.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            12897..13253
                     /gene="rpsM"
                     /locus_tag="LSX49_003554"
     CDS             12897..13253
                     /gene="rpsM"
                     /locus_tag="LSX49_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBL7169916.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            13270..13659
                     /gene="rpsK"
                     /locus_tag="LSX49_003555"
     CDS             13270..13659
                     /gene="rpsK"
                     /locus_tag="LSX49_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBL7169917.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADVVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            13693..14313
                     /gene="rpsD"
                     /locus_tag="LSX49_003556"
     CDS             13693..14313
                     /gene="rpsD"
                     /locus_tag="LSX49_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBL7169918.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            14339..15328
                     /gene="rpoA"
                     /locus_tag="LSX49_003557"
     CDS             14339..15328
                     /gene="rpoA"
                     /locus_tag="LSX49_003557"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBL7169919.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            15369..15752
                     /gene="rplQ"
                     /locus_tag="LSX49_003558"
     CDS             15369..15752
                     /gene="rplQ"
                     /locus_tag="LSX49_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBL7169920.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            15859..16227
                     /locus_tag="LSX49_003559"
     CDS             15859..16227
                     /locus_tag="LSX49_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HBL7169921.1"
                     /translation="MWLLDQWAERHIAEAQAKGEFDNLVGSGEPLILDDDSHVPPELR
                     AGYRLLKNAGCLPPELEHRREAIQLLDILKGIRHDDPQYQEVSRRLSLLELKLRQAGL
                     STDFLRGDYADKLLNKINDN"
     gene            16238..16663
                     /gene="zntR"
                     /locus_tag="LSX49_003560"
     CDS             16238..16663
                     /gene="zntR"
                     /locus_tag="LSX49_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HBL7169922.1"
                     /translation="MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQRSLQRLNDTCCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            16719..16937
                     /gene="arfA"
                     /locus_tag="LSX49_003561"
     CDS             16719..16937
                     /gene="arfA"
                     /locus_tag="LSX49_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor ArfA"
                     /protein_id="HBL7169923.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSDAC"
     gene            complement(16934..17347)
                     /gene="mscL"
                     /locus_tag="LSX49_003562"
     CDS             complement(16934..17347)
                     /gene="mscL"
                     /locus_tag="LSX49_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBL7169924.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLREAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAATPAPTKEEVLLTEIRDLLKEQNNRS"
     gene            complement(17477..18853)
                     /gene="trkA"
                     /locus_tag="LSX49_003563"
     CDS             complement(17477..18853)
                     /gene="trkA"
                     /locus_tag="LSX49_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HBL7169925.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            complement(18875..>20150)
                     /gene="rsmB"
                     /locus_tag="LSX49_003564"
     CDS             complement(18875..>20150)
                     /gene="rsmB"
                     /locus_tag="LSX49_003564"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBL7169926.1"
                     /translation="NLRSMAAQAIEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCF
                     GVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAV
                     AIKRPQLKGLINGVLRQFQRQQDELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIV
                     EANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVQLETPAPVHALPGF
                     EEGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVLAVDIDEQ
                     RLSRVYDNLKRLGMKATVKQGDGRNPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKW
                     LRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQRTADAE
                     LCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
BASE COUNT         5168 a         4750 c         5320 g         4912 t
ORIGIN      
        1 ggttgcgtga gaagcatcag acctggcgtc tgtgctattt gttgggtgag gctggaagtg
       61 gaaaaacccg gctggcgcag caactacaaa aagataaaca tcgccgtgtg attactttaa
      121 gcctcgttgt ttcctggcaa ggtaaggccg catggatcgt taccgacgat aatgcggctg
      181 aacagggctg ccgtgacagc gcctggacgc gagatgagat ggcgggtcaa ttactgcatg
      241 cacttcatcg aactgatagt cgctgccctc ttattattat tgaaaatgct cacctgaatc
      301 accgccgcat acttgatgat ctccaacgcg cgatatctct tattcctgac ggtcaatttt
      361 tgctgatcgg cagacccgat cgaaaagtcg aacgtgattt taaaaaacag ggcattgaac
      421 ttgtctcgac aggtcgtctg acggagcacg agcttaaggc aagcatcctt gaaggtcaga
      481 atattgacca gcccgatctc cttttaaccg ccagagttct gaaacggata gctttattat
      541 gtcggggaga tcgcagaaag ctggcgcttg ccggcgaaac aattagctta ttacagcaag
      601 ccgagcagac ctgcgttttc actgcaaaac aatggcgaat gatttaccgc gtattaggtg
      661 ataaccgccc ccggaaaatg cagcttgccg tggtgatgag tggaaccatt atcgcactta
      721 cctgtggttg gctactgctg ccctctttca cagctccgtt acccgttcct gcgtggctga
      781 tacccgtaac gccagtagtt aaacaagata tgactaagga tattgcccat gtggtgatgc
      841 gcgatagtga ggcgctaagc gtgttatacg gcgtatgggg gtacgaggtc ccagccgatt
      901 cggcctggtg cgatcaggca gtaagagcgg ggctggtatg taaaagtggg aatgcttctt
      961 tacaaacatt ggtagatcag aatttgccct ggatcgcatc gcttaaagtc ggggacaaaa
     1021 aattgcctgt tgtggtcgtt cgcgtcggtg atgctaccgt tgatgtactc gtagggcagc
     1081 aaacctggac gctgacacat aaatggtttg agttggtatg gacgggtgat tatcttctgt
     1141 tgtggaaaat gtcgccggaa ggagagagta ccattacgcg tgatagcagc gaggaagaga
     1201 ttctctggct ggaaacgatg ttaaaccgcg cattgcatat ttcgacagaa tcttcggcag
     1261 agtggcgtcc cttgttggta gaaaaaataa agcaatttca aaaaagccat cacttgaaaa
     1321 ctgacggtgt tgttggcttt tcaacgttag tgcatctctg gcaggtggca ggggagagtg
     1381 cctacttata tcgggatgaa gcaaatattt ccccggaaac aacagtgaag gggaaatgac
     1441 atgtttgaat tctatatcgc cgcgcgtgag cagaaagaaa caggtcaccc tggtatcttc
     1501 tcccgacaaa aacacagcac cataatatat gtcatttgtt tattgctgat ttgcctgtgg
     1561 tttgcaggaa tggtgttggt tggtgggtat gcccggcagc tatgggcact ttggatagta
     1621 aaagcagaag tcactgtaga tgctgaaacg cccgctttta aacaatcaac acaacactat
     1681 tttttcaaaa aacagccact ccccgtcgtc gaatccgtcg aggaggaaga tgacccagga
     1741 gtcgcggttg agaatgcccc ctcttcttct gaagacgaag acaatactgt agaagaaagc
     1801 gacgagaaag ccggtttaag agagcgtgtc aaaaatgcgc tgaacgaact tgagagataa
     1861 cccaaaggct gtttacttta ctagcaatac gcttgcgttc ggtggttaag tatgtataat
     1921 gcgcgggctt gtcgtagttg acagcaggtt caatctgaac ctcagttagc cgaatttggc
     1981 tacctaacaa tgctcccaat cggggagcta cgtaagaacg gttacactct cccatcaatc
     2041 gtaatgggtc tgaggagtaa tcattttcgt ttataaaata attggagctc tggtctcatg
     2101 cagaaccaaa gaatccgtat ccgcctgaaa gcgtttgatc atcgtctgat cgatcaagca
     2161 accgcggaaa tcgtcgagac tgctaagcgc actggtgcgc aggtccgtgg tccgatcccg
     2221 ctgccgacac gcaaagagcg cttcactgtt ctgatctccc cgcacgtcaa caaagacgcg
     2281 cgcgatcagt acgaaatccg tactcacttg cgtctggttg acatcgttga gccaaccgag
     2341 aaaaccgttg atgctctgat gcgtctggat ctggctgccg gtgtagacgt gcagatcagc
     2401 ctgggttaat caggtcattg agcgattgag aggttgaaac aatgattggt ttagtcggta
     2461 aaaaagtggg tatgacccgt atcttcacag aagacggcgt ttctatccca gtaaccgtaa
     2521 tcgaagttga agcaaaccgc gttactcagg ttaaagacct ggctaacgat ggctaccgtg
     2581 ctattcaggt gaccaccggt gctaaaaaag ctaaccgtgt gaccaagcct gaagctggcc
     2641 acttcgctaa agctggcgta gaagctggcc gtggtctgtg ggaattccgc ctggctgaag
     2701 gcgaagagtt cactgtaggt cagagcatta gcgttgaact gtttgctgac gttaaaaaag
     2761 ttgacgtaac tggcacctct aaaggtaaag gtttcgcagg taccgttaag cgctggaact
     2821 tccgtaccca ggacgctact cacggtaact ccttgtctca ccgcgttccg ggttctatcg
     2881 gtcagaacca gactccgggc aaagtgttca aaggcaagaa aatggcaggt cagatgggta
     2941 acgaacgtgt aaccgttcag agccttgacg tagtacgcgt tgacgctgag cgcaacctgc
     3001 tgctggttaa aggcgctgtc ccgggtgcaa ccggtagcga cctgatcgtt aaaccagctg
     3061 tgaaggcgta aggagatagc aatggaatta gtattgaaag acgcgcagag cgcgctgact
     3121 gtttccgaaa ctaccttcgg tcgtgatttc aacgaagcgc tggttcacca ggttgttgtt
     3181 gcttatgcag ctggtgctcg tcagggtact cgtgctcaga agactcgtgc tgaagtaact
     3241 ggttccggta aaaaaccgtg gcgccagaaa ggcaccggcc gtgcgcgttc tggttctatc
     3301 aagagcccga tctggcgttc tggtggcgtg acctttgctg ctcgtccgca ggaccacagt
     3361 caaaaagtta acaagaagat gtaccgcggc gcgctgaaaa gcatcctgtc cgaactggta
     3421 cgtcaggatc gtctgatcgt tgtcgagaag ttctctgtag aagcgccgaa aactaagctg
     3481 ctggcacaga aactgaaaga catggctctg gaagatgtgc tgatcatcac cggtgagctg
     3541 gacgagaacc tgttcctggc tgcgcgcaac ctgcacaagg ttgacgtacg cgatgcaact
     3601 ggtatcgacc cggttagcct gatcgccttc gacaaagtcg taatgactgc tgatgctgtt
     3661 aagcaagttg aggagatgct ggcatgattc gtgaagaacg tctgctgaag gtgctgcgtg
     3721 caccgcacgt ttctgaaaaa gcgtctactg cgatggaaaa atccaacacc atcgtactca
     3781 aagttgctaa agacgcgacc aaagcagaaa tcaaagctgc tgtgcagaaa ctgtttgaag
     3841 tcgaagtcga agtcgttaac accctggtag ttaaagggaa agttaaacgt cacggacagc
     3901 gtatcggtcg tcgtagcgac tggaaaaaag cttacgtcac cctgaaagaa ggccagaatc
     3961 tggacttcgt tggcggcgct gagtaagtcg gaggagtaat acaatggcag ttgttaaatg
     4021 taaaccgaca tctccgggtc gtcgccacgt agttaaagtg gttaaccctg agctgcacaa
     4081 gggcaaacct tttgctccgt tgctggaaaa aaacagcaaa tccggtggtc gtaacaacaa
     4141 tggccgtatc accactcgtc atatcggtgg tggccacaag caggcttacc gtattgttga
     4201 cttcaaacgc aacaaagacg gtatcccggc agttgttgaa cgtcttgagt acgatccgaa
     4261 ccgttccgcg aacatcgcgc tggttctgta caaagacggt gaacgccgtt acatcctggc
     4321 ccctaaaggc ctgaaagctg gcgaccagat tcagtctggc gttgatgctg caatcaaacc
     4381 aggtaacacc ctgccgatgc gcaacatccc ggttggttct actgttcata acgtagaaat
     4441 gaaaccaggt aaaggcggtc agctggcacg ttccgctggt acttacgttc agatcgttgc
     4501 tcgtgatggt gcttatgtca ccctgcgtct gcgttctggt gaaatgcgta aagtagaagc
     4561 agactgccgt gcaactctgg gcgaagttgg caatgctgag catatgctgc gcgttctggg
     4621 taaagcaggt gctgcacgct ggcgtggtgt tcgtccgacc gttcgcggta ccgcgatgaa
     4681 cccggtagac cacccacatg gtggtggtga aggtcgtaac tttggtaagc acccggtaac
     4741 tccgtggggc gttcagacca aaggtaagaa gacccgcagc aacaagcgta ctgataaatt
     4801 catcgtacgt cgccgtagca aataatttta gaggataagc catgccacgt tctctcaaga
     4861 aaggtccttt tattgacctg cacttgctga agaaggtaga gaaagcggtg gaaagcggag
     4921 acaagaagcc cctgcgcact tggtcccgtc gttcaacgat ctttcctaac atgatcggtt
     4981 tgaccatcgc tgtccataat ggtcgtcagc acgttccggt atttgtaacc gacgaaatgg
     5041 tcggtcacaa actgggtgaa ttcgcaccga ctcgtactta tcgcggccac gctgctgata
     5101 aaaaagcgaa gaagaaataa ggtaggagga agagatggaa actatcgcta aacatcgcca
     5161 tgctcgttct tctgctcaga aggttcgcct tgttgctgac ctgattcgcg gtaagaaagt
     5221 gtcgcaggct ctggatattt tgacctacac caacaagaaa gcggctgtac tggtcaagaa
     5281 agttctggaa tctgccattg ctaacgctga acacaacgat ggcgctgaca ttgacgatct
     5341 gaaagttacg aaaattttcg tagacgaagg cccgagcatg aagcgcatta tgccgcgtgc
     5401 aaaaggtcgt gcagatcgca tcctgaagcg caccagccac atcactgtgg ttgtgtccga
     5461 tcgctgagac tctggagact agcaatgggt cagaaagtac atcctaatgg tattcgcctg
     5521 ggtattgtaa aaccatggaa ctctacctgg tttgcgaaca ccaaagaatt cgctgacaac
     5581 ctggacagcg attttaaagt acgtcagtac ctgactaagg aactggctaa agcgtccgta
     5641 tctcgtatcg ttatcgagcg tccggctaag agcatccgtg taaccattca cactgctcgc
     5701 ccgggtatcg ttatcggtaa aaaaggtgaa gacgtagaaa aactgcgtaa ggtcgtagcg
     5761 gacatcgctg gcgttcctgc acagatcaac atcgccgaag ttcgtaagcc tgaactggac
     5821 gcaaaactgg ttgctgacag catcacttct cagctggaac gtcgcgttat gttccgtcgt
     5881 gctatgaagc gtgctgtaca gaacgcaatg cgtctgggcg ctaaaggtat taaagttgaa
     5941 gttagcggcc gtctgggcgg cgcggaaatc gcacgtaccg aatggtaccg cgaaggtcgc
     6001 gtaccgctgc acactctgcg tgctgacatc gactacaaca cctctgaagc gcacaccact
     6061 tacggtgtaa tcggcgttaa agtgtggatc ttcaaaggcg agatcctggg tggtatggct
     6121 gctgttgaac aaccggaaaa accggctgct cagcctaaaa agcagcagcg taaaggccgt
     6181 aaataaggag cgtcgctgat gttacaacca aagcgtacaa aattccgtaa aatgcacaaa
     6241 ggccgtaacc gcggtctggc gcagggtacg gatgttagct tcggcagctt cggtctgaaa
     6301 gctgttggcc gtggtcgtct gactgcacgt cagatcgaag cagcacgtcg tgctatgacc
     6361 cgtgcagtta agcgtcaagg taagatctgg atccgtgtgt tcccggacaa accgatcact
     6421 gaaaagccgc tggcagtgcg tatgggtaaa ggtaaaggta acgtggagta ttgggttgcc
     6481 ttgattcagc cgggtaaagt cctgtatgaa atggacggtg ttccggaaga gctggcccgt
     6541 gaagcattca agctggcagc agcgaaactg ccgattaaaa ccacctttgt aactaagacg
     6601 gtgatgtaat gaaagcaaaa gagctgcgtg agaagagcgt tgaagagctg aacaccgagc
     6661 tgctgaacct gctgcgtgag cagttcaacc tgcgtatgca ggctgcaagt ggccagctgc
     6721 aacagtctca cctgttgaag caagtgcgtc gcgatgtcgc acgcgttaag actttactga
     6781 acgagaaggc gggtgcgtaa tgaccgataa aatccgtact ctgcaaggtc gcgttgttag
     6841 cgacaaaatg gagaaatcca ttgttgttgc tatcgaacgt tttgtgaaac acccgatcta
     6901 cggtaaattc atcaagcgta cgaccaaact gcacgtacat gacgagaaca acgaatgcgg
     6961 tatcggtgac gtggttgaaa tccgcgaatg ccgtccgctg tccaagacta aatcctggac
     7021 gctggttcgc gttgtagaga aagcggttct gtaatacagt acactctctc gatacgaata
     7081 aacggctcag aaatgagccg tttatttttt ctacccatat ccttgaagcg gtgttataat
     7141 gccgcgccct cgatatgggg atttttaacg acctgatttt cgggtctcag tagtagttga
     7201 cattagcgga gcactaaaat gatccaagaa cagactatgc tgaacgtcgc cgacaactcc
     7261 ggtgcacgtc gcgtaatgtg tatcaaggtt ctgggtggct cgcaccgtcg ctacgcaggc
     7321 gtaggcgata tcatcaagat caccatcaaa gaagcaattc cgcgtggtaa ggtcaaaaaa
     7381 ggtgatgtgc tgaaggcggt agtggtgcgc accaagaagg gtgttcgtcg cccggacggt
     7441 tctgtcattc gcttcgatgg taatgcttgt gttcttctga acaacaacag cgagcagcct
     7501 atcggtacgc gtatttttgg gccggtaact cgtgagcttc gtagtgagaa gttcatgaaa
     7561 attatctctc tggcaccaga agtactctaa ggagcgaatc atggcagcga aaatccgtcg
     7621 tgatgacgaa gttatcgtgt taaccggtaa agataaaggt aaacgcggta aagttaagaa
     7681 tgtcctgtct tccggcaagg tcattgttga aggtatcaat ctggttaaga aacatcagaa
     7741 gccggttccg gccctgaacc aaccgggtgg catcgttgaa aaagaagccg ctattcaggt
     7801 ttccaacgta gcaatcttca atgcgacaac cggcaaggct gaccgtgtag gctttagatt
     7861 cgaagacggt aaaaaagtcc gtttcttcaa gtctaacagc gaaactatca agtaatttgg
     7921 agtagtacga tggcgaaact gcatgattac tacaaagacg aagtagttaa aaaactcatg
     7981 actgagttta actacaattc tgtcatgcaa gtccctcggg tcgagaagat caccctgaac
     8041 atgggtgttg gtgaagcgat cgctgacaaa aaactgctgg ataacgcagc agcagacctg
     8101 gcagcaatct ccggtcaaaa accgctgatc accaaagcac gcaaatctgt tgcaggcttc
     8161 aaaatccgtc agggctatcc gatcggctgt aaagtaactc tgcgtggcga acgcatgtgg
     8221 gagttctttg agcgcctgat cactattgct gtacctcgta tccgtgactt ccgtggcctg
     8281 tccgctaagt ctttcgacgg tcgtggtaac tacagcatgg gtgtccgtga gcagatcatc
     8341 ttcccagaaa tcgactacga taaagtcgac cgcgttcgtg gtttggatat taccattacc
     8401 actactgcga aatctgacga agaaggccgc gctctgctgg ctgcctttga cttcccgttc
     8461 cgcaagtaag gtagggttac taaatggcta agcaatcaat gaaagcacgc gaagtaaaac
     8521 gcgtagcttt agctgataaa tacttcgcga aacgcgctga actgaaagcg atcatctctg
     8581 atgtgaacgc ttccgacgaa gatcgttgga acgctgttct caagctgcag actctgccgc
     8641 gtgattccag cccgtctcgt cagcgtaacc gctgccgtca aacaggtcgt ccgcatggtt
     8701 tcctgcggaa gttcgggttg agccgtatta aggtccgtga agccgctatg cgcggtgaaa
     8761 tcccgggtct gaaaaaggct agctggtaat tgtcaccaat tgaatcacgg gagtaaagac
     8821 agatgagcat gcaagatccg atcgcggata tgctgacccg tatccgtaac ggtcaggccg
     8881 cgaacaaagc tgcggtcacc atgccttcct ccaagctgaa agtggcaatc gccaacgtgc
     8941 tgaaggaaga aggttttatt gaagatttta aagttgaagg cgacaccaag cctgaactgg
     9001 aacttactct gaagtatttc cagggcaaag ctgttgtaga aagcattcag cgtgtcagcc
     9061 gcccaggtct gcgcatctat aaacgtaaag atgagctgcc gaaagttatg gcgggtctgg
     9121 gtatcgcagt tgtttctacc tctaaaggtg ttatgactga tcgtgcagcg cgccaggctg
     9181 gtcttggtgg cgaaattatc tgctacgtag cctaatcgga ggaaaaaatg tctcgtgttg
     9241 ctaaagcacc ggtcgttgtt cctgccggcg ttgacgtaaa aatcaacggt caggttatta
     9301 cgatcaaagg taaaaacggc gagctgactc gtactctcaa cgatgctgtt gaagttaaac
     9361 atgcagataa taccctgacc ttcggtccgc gtgatggtta cgcagacggt tgggcacagg
     9421 ctggtaccgc gcgtgccctg ctgaactcaa tggttatcgg tgttaccgaa ggcttcacta
     9481 agaagctgca gctggttggt gtaggttacc gtgcagcggt taaaggcaat gtgattaacc
     9541 tgtctctggg tttctctcat cctgttgacc atcagctgcc tgcgggtatc actgctgaat
     9601 gtccgactca gactgaaatc gtgctgaaag gcgctgataa gcaggtgatc ggccaggttg
     9661 cagcggatct gcgcgcctac cgtcgtcctg agccttacaa aggcaagggt gttcgttacg
     9721 ccgacgaagt cgtgcgtacc aaagaggcta agaagaagta aggtaacact atggataaga
     9781 aatctgctcg tatccgtcgt gcgacccgcg cacgccgcaa gctccaggag ctgggcgcaa
     9841 ctcgcctggt ggtacatcgt accccgcgtc acatttacgc acaggtaatt gcaccgaacg
     9901 gttctgaagt tctggtagct gcttctactg tagaaaaagc tatcgctgaa caactgaagt
     9961 acaccggtaa caaagacgcg gctgcagctg tgggtaaagc tgtcgctgaa cgcgctctgg
    10021 aaaaaggcat caaagatgta tcctttgacc gttccgggtt ccaatatcat ggtcgtgtcc
    10081 aggcactggc agatgctgcc cgtgaagctg gccttcagtt ctaaggtaga ggtgtaagat
    10141 ggctcacatc gaaaaacaag ctggcgaact gcaggaaaag ctgatcgcgg taaaccgcgt
    10201 atctaaaacc gttaaaggtg gtcgtatttt ctccttcaca gctctgactg tagttggcga
    10261 tggtaacggt cgcgttggtt ttggttacgg taaagcgcgt gaagttccag cagcgatcca
    10321 gaaagcgatg gaaaaagccc gtcgcaatat gattaacgtc gcgctgaata acggcactct
    10381 gcaacaccct gttaaaggtg ttcacacggg ttctcgcgta ttcatgcagc cggcttccga
    10441 gggtaccggt atcatcgccg gtggtgcaat gcgcgccgtt ctggaagtcg ctggggttca
    10501 taacgttctg gctaaagcgt atggttccac caacccgatt aacgtggttc gtgcaactat
    10561 cgatggcctg gaaaatatga attctccaga aatggtcgct gccaagcgtg gtaaatccgt
    10621 tgaagaaatt ctggggaaat aaaccatggc aaagactatt aaaattactc aaacccgcag
    10681 tgcaatcggt cgtctgccga aacacaaggc aacgctgctt ggcctgggtc tgcgtcgtat
    10741 tggtcacacc gtagagcgcg aggatactcc tgctattcgc ggtatgatca acgcggtttc
    10801 cttcatggtt aaagttgagg agtaagagat gcgtttaaat actctgtctc cggccgaagg
    10861 ctccaaaaag gcgggtaaac gcctgggtcg tggtatcggt tctggcctcg gtaaaaccgg
    10921 tggtcgtggt cacaaaggtc agaaatctcg ttctggcggt ggcgtacgtc gcggtttcga
    10981 gggtggtcag atgcctctgt accgtcgtct gccgaaattc ggcttcactt ctcgtaaagc
    11041 agcgattaca gccgaagttc gtctgtctga cctggctaaa gtagaaggcg gtgttgtaga
    11101 cctgaacacg ctgaaagcgg ctaacattat cggtatccag atcgagttcg cgaaagtgat
    11161 cctggctggc gaagtaacga ctccggtaac tgttcgtggc ctgcgtgtta ctaaaggcgc
    11221 tcgtgctgct atcgaagctg ctggcggtaa aatcgaggaa taagtagcag atggctaaac
    11281 aaccgggatt agattttcaa agtgccaaag gtggcttagg cgagctgaaa cgcagactgc
    11341 tgtttgttat cggtgcgctg attgtgttcc gtattggctc ttttattccg atccctggta
    11401 ttgatgccgc tgtacttgcc aaactgcttg agcaacagcg aggcaccatc attgagatgt
    11461 ttaacatgtt ctctggtggt gctctcagcc gtgcttctat ctttgctctg gggatcatgc
    11521 cgtatatttc ggcgtcgatc attatccagc tactgacggt ggttcatcca acgttggcag
    11581 aaattaagaa agaaggggag tctggtcgtc gtaagatcag ccagtacacc cgctacggta
    11641 ctctggtgct ggcaatattc cagtcgatcg gtattgctac tggtctgccg aatatgcctg
    11701 gtatgcaagg cctggtgatt aacccgggct ttgcattcta cttcaccgct gttgtaagtc
    11761 tggtcacagg aaccatgttc ctgatgtggt tgggcgaaca gatcactgaa cgaggtatcg
    11821 gcaacggtat ttcaatcatt atcttcgccg gtattgtcgc gggactcccg ccagccattg
    11881 cccatactat cgagcaagcg cgtcaaggcg acctgcactt cctcgtgttg ctgttggttg
    11941 cagtattagt atttgcagtg acgttctttg ttgtatttgt tgagcgtggt caacgccgca
    12001 ttgtggtaaa ctacgcgaaa cgtcagcaag gtcgtcgtgt ctatgctgca cagagcacac
    12061 atttaccgct gaaagtgaat atggcggggg taatcccggc aatcttcgct tccagtatta
    12121 ttctgttccc ggcgaccatc gcgtcatggt tcgggggcgg tactggttgg aactggctga
    12181 caacaatttc gctgtatttg cagcctgggc aaccgcttta tgtgttactc tatgcgtctg
    12241 caatcatctt cttctgtttc ttctacacgg cgttggtttt caacccgcgt gaaacagcag
    12301 ataacctgaa gaagtccggt gcatttgtac caggaattcg tccgggagag caaacggcga
    12361 agtatatcga taaagtaatg acccgcctga ccttggttgg tgcgctgtac attaccttta
    12421 tctgcctgat cccggagttc atgcgtgatg caatgaaagt accgttctac ttcggtggga
    12481 cctcactgct tatcgttgtt gtcgtgatta tggactttat ggctcaagtg caaactctga
    12541 tgatgtccag tcagtatgag tctgcattga agaaggcgaa cctgaaaggc tacggccgat
    12601 aattggtcgc ccgagaagtt acggagagta aaaatgaaag ttcgtgcttc cgtcaagaaa
    12661 ttatgccgta actgcaaaat cgttaagcgt gatggtgtca tccgtgtgat ttgcagtgcc
    12721 gagccgaagc ataaacagcg ccaaggctga ttttttcgca tatttttctt gcaaagttgg
    12781 gttgagctgg ctagattagc cagccaatct tttgtatgtc tgtgcgtttc catttgagta
    12841 tcctgaaaac gggcttttca gcatggaacg tacatattaa atagtaggag tgcatagtgg
    12901 cccgtatagc aggcattaac attcctgatc ataagcatgc cgtaatcgca ttaacttcga
    12961 tttatggcgt cggcaagacc cgttctaaag ccatcctggc tgcagcgggt atcgctgaag
    13021 atgttaagat cagtgagctg tctgaaggac aaatcgacac gctgcgtgac gaagttgcca
    13081 aatttgtcgt tgaaggtgat ctgcgccgtg aaatcagcat gagcatcaag cgcctgatgg
    13141 atcttggttg ctatcgcggt ttgcgtcatc gtcgtggtct cccggttcgc ggtcagcgta
    13201 ccaagaccaa cgcacgtacc cgtaagggtc cgcgcaaacc gatcaagaaa taatcggggt
    13261 gattgaataa tggcaaaggc accaattcgt gcacgtaaac gtgtaagaaa acaagtctct
    13321 gacggcgtgg ctcatatcca tgcttctttc aacaacacca tcgtgactat cactgatcgt
    13381 cagggtaacg cgttgggttg ggcaacagcc ggtggttccg gtttccgtgg ttctcgcaaa
    13441 tccactccgt ttgcagcaca ggttgcagca gagcgttgcg ctgacgtcgt gaaagaatac
    13501 ggcatcaaga atctggaagt tatggttaaa ggtccgggtc caggccgcga atctactatt
    13561 cgtgctctga acgccgcagg tttccgcatc actaacatta ctgatgtgac tccgatccct
    13621 cataacggtt gtcgtccgcc gaaaaaacgt cgcgtataac gcctcgtttt ccaggtttgt
    13681 tggagaaaga aaatggcaag atatttgggt cctaagctca agctgagccg tcgtgagggc
    13741 accgacttat tccttaagtc tggcgttcgc gcgatcgata ccaagtgtaa aattgaacaa
    13801 gctcctggcc agcacggtgc gcgtaaaccg cgtctgtctg actatggtgt gcagttgcgt
    13861 gaaaagcaaa aagttcgccg tatctatggt gtgctggagc gtcagttccg taactactac
    13921 aaagaagcag cacgtctgaa aggcaacacc ggtgaaaacc tgttggctct gctggaaggt
    13981 cgtctggaca acgttgtata ccgtatgggc ttcggtgcca ctcgtgcaga agcacgtcag
    14041 ctggttagcc ataaagcaat tatggtaaac ggtcgtgttg ttaacatcgc ttcttatcag
    14101 gttagtccga atgacgttgt aagcattcgt gagaaagcga agaagcagtc tcgcgtgaaa
    14161 gccgctctgg agctggctga gcagcgtgaa aagccaacct ggctggaagt tgatgctggc
    14221 aagatggaag gtacgtttaa gcgtaagccg gagcgttctg atctgtctgc ggacattaac
    14281 gaacacctga tcgtcgagct ttactccaag taaagcttag taccaaagag aggacacaat
    14341 gcagggttct gtgacagagt ttctaaaacc gcgcctggtt gatatcgagc aagtgagttc
    14401 gacgcacgcc aaggtgaccc ttgagccttt agagcgtggc tttggccata ctctgggtaa
    14461 cgcactgcgc cgtattctgc tctcatcgat gccgggttgc gcggtgaccg aggttgagat
    14521 tgatggtgta ctacatgagt acagcaccaa agaaggcgtt caggaagata tcctggaaat
    14581 cctgctcaac ctgaaagggc tggcggtgag agttcagggc aaagatgaag ttattcttac
    14641 cttgaataaa tctggcattg gccctgtgac tgcagccgat atcacccacg acggtgatgt
    14701 cgaaatcgtc aagccgcagc acgtgatctg ccacctgacc gatgagaacg cgtctattag
    14761 catgcgtatc aaagttcagc gcggtcgtgg ttatgtgccg gcttctaccc gaattcattc
    14821 ggaagaagat gagcgcccaa tcggccgtct gctggtcgac gcatgctaca gccctgtgga
    14881 gcgtattgcc tacaatgttg aagcagcgcg tgtagaacag cgtaccgacc tggacaagct
    14941 ggtcatcgaa atggaaacca acggcacaat cgatcctgaa gaggcgattc gtcgtgcggc
    15001 aaccattctg gctgaacaac tggaagcttt cgttgactta cgtgatgtac gtcagcctga
    15061 agtgaaagaa gagaaaccag agttcgatcc gatcctgctg cgccctgttg acgatctgga
    15121 attgactgtc cgctctgcta actgccttaa agcagaagct atccactata tcggtgatct
    15181 ggtacagcgt accgaggttg agctccttaa aacgcctaac cttggtaaaa aatctcttac
    15241 tgagattaaa gacgtgctgg cttcccgtgg actgtctctg ggcatgcgcc tggaaaactg
    15301 gccaccggca agcatcgctg acgagtaacc ggatcacagg ttaaggtttt actgagaagg
    15361 ataaggtcat gcgccatcgt aagagtggtc gtcaactgaa ccgcaacagc agccatcgcc
    15421 aggctatgtt ccgcaatatg gcaggttcac tggttcgtca tgaaatcatc aagacgactc
    15481 tgcctaaagc gaaagagctg cgccgcgtag ttgagccgct gattactctt gccaagactg
    15541 atagcgttgc taatcgtcgt ctggcattcg cccgtactcg tgataacgag atcgtggcaa
    15601 aactgtttaa cgaactgggc ccgcgtttcg cgagccgtgc cggtggttac actcgtattc
    15661 tgaagtgtgg cttccgtgca ggcgacaatg cgccgatggc ttacatcgag ctggttgatc
    15721 gttcagagaa agcagaagct gctgcagagt aatctgaagc aacgtaaaaa aacccgcccc
    15781 ggcgggtttt tttatacccg tagcatcccc acttatctac aatagctgta ctctttttgt
    15841 tcatcccctg gagtatttat gtggttactt gaccagtggg cagagcgtca tatagcagaa
    15901 gcgcaagcga aaggtgagtt tgataacctg gtaggtagcg gcgaaccatt gatactggat
    15961 gatgattctc atgtgccacc ggaattacgt gcggggtatc gcttgctgaa gaatgctggt
    16021 tgcttaccgc cagaacttga gcataggagg gaagcaatac agcttctgga tattctcaaa
    16081 ggtatccgtc atgatgatcc gcaatatcaa gaggttagtc gtcgattgtc attactggaa
    16141 ttgaagctgc gacaagctgg attgagtacc gattttttac gcggcgatta tgctgacaag
    16201 ttgttgaaca aaatcaacga taactagtgg agtatgtatg tatcgcattg gtgagctggc
    16261 aaaaatggcg gaagtaacac ccgacacgat tcgttattac gaaaagcagc agatgatgga
    16321 gcatgaagta cgcaccgaag gtgggtttcg cctgtatacc gaaagcgatc tccagcgatt
    16381 gaaatttatc cgccatgcca gacaactagg tttcagtctg gagtcgatcc gcgagttgct
    16441 gtcgatccgt atcgatcctg aacaccatac ctgtcaggag tcaaaaggca ttgtgcagga
    16501 aagattgcag gaagtcgaag ctcgtatagc cgagttgcag agtatgcagc gttccttgca
    16561 acgccttaat gatacctgtt gtgggaccgc ccatagcagt gtttattgct cgattcttga
    16621 agctcttgaa caaggggcga gtggcgttaa gagtggctgt tgattttttg cactggcagg
    16681 attacactcg cgccgttaaa taaccaattg gagtttttat gagccgatat cagcatacta
    16741 aagggcagat aaaggataat gcgatagaag cattactaca tgatccctta ttccgacagc
    16801 gagtagagaa aaataagaaa gggaaaggca gttacatgcg aaaaggaaaa catggcaatc
    16861 gggggaactg ggaggccagt ggcaagaaag taaatcactt ttttaccact ggccttctgc
    16921 tttcagacgc ttgttaagag cggttattct gctctttcag caaatcacga atttctgtca
    16981 gtaatacttc ttctttagtt ggtgcaggtg ttgctgctgc tggttcttct tttttccgat
    17041 tcagtttgtt gattagctta atcgccataa agatggcaaa ggccactatc agaaaatcaa
    17101 agacgttttg aatgaagaca ccgtaatgca tcacaacagc agggatatcc ccttgggcct
    17161 cgcgtagcgt gacagcaaac tgtttaaagt cgatcccgcc aattaataag cccagaggtg
    17221 gcatgatgat atcggcaacc agtgaagata caatcttccc gaatgccgct ccgataatga
    17281 cacccactgc caaatccacc acgttcccgc gcatcgcaaa ttcgcgaaat tctttaataa
    17341 tgctcatgtt attctcccta tgaagccgac aaccataagt ctaacaaatg ttaagccatt
    17401 ttcctgccag gaatggattt aattaatcct taataatcaa agggaaataa taaggcgtca
    17461 ttagacgcct tattaattac aagaagaaag gacttggctg gaagagtctt tcgacgtcgg
    17521 taataaactt tttatctgtg aggaacataa ttacgtgatc gccttgctca atgcgcagat
    17581 tgtcattggc aatcatcaca tcgtttccac gtaccaccgc tccaataatc gttcctggcg
    17641 gtagcttgat ttcgtcaatg actctgccga caacgcgtga ggtgctttca tcaccgtgag
    17701 caacggcttc aatagcttct gctacgccgc ggcgtaatga ggaaacacca acaatatctg
    17761 cttttcgcac atggctaagc aacgcagaaa tagttgcttg ttgtggtgaa atcgcaatat
    17821 cgatcacgct cccctgaacc agatccacat aagcgcgacg ttggatcaat accatcacct
    17881 ttttcgcacc catacgtttg gcaagcatgg cggacatgat attggcctcg tcatcgttgg
    17941 tgacggcaat aaacagatca acttgatcga tatgttcttc ggccagcagt tcttgatccg
    18001 acgcatcacc aaaaaagacg atcgtattct gcaacttttc cgccagttcg gcagcgcgct
    18061 gctgattacg ttcgatgagt ttaacgctgt aatctttttc cagacgacgc gccagccctg
    18121 caccgatatt accgccacca accagcatga tccgcttata cggtttttcc agtcgctgta
    18181 attcactcat caccgcacgg atatgctgtg aagcggcaat aaagaacact tcatcaccag
    18241 cttcaacaat ggtcgaacct tgcggacgaa tggggcgatc gtggcggaaa attgctgcca
    18301 cacgagtatc gatatgtggc atatgttcgc gcatggtcga aagtgcatta ccaatcagcg
    18361 ggccgccata ataggcttta accacagcca ggctgacttt accctcagcg aagttcacca
    18421 cctgcaatgc gccgggatac tcaatcagtc ggtaaatatt atcgataacc aactgctctg
    18481 gtgcgatcag atgatcaatc ggtacagcat ctgaatgaaa tagtttatcg gcatcgcgca
    18541 cgtagtctgg tgagcggata cgagcgatgc gattaggggt gttgaaaagt gagtaggcta
    18601 cctggcaggc aaccatattg gtttcatctg aactggttac agcaaccagc atatcggcgt
    18661 cgtcggcacc tgcctcccgc aatacgcgtg gatgagagcc atgcccctgc acgacccgca
    18721 ggtcaaattt atcctgtaag gtccgcagac gctcaccgtt ggtatcgaca acagtaatat
    18781 cgttgttctc gccaaccagg ttttccgcca gtgtgccgcc aacctggccg gcacccagaa
    18841 tgataatttt catcagtcgc gacccgttat ctcatcactt tttgattagc ttagcgtaaa
    18901 agaagccgtc gccctcttcg gcaccgggca aattttgttt acccggttgc tctggtgttc
    18961 ctgtttcaca aagttcggca tcagcggtac gttgcaaaaa ggctttaatc tgcaggctat
    19021 tttcttccgg taacaccgaa caggtggcat agaccagggt tccaccggat tttaaatgtg
    19081 gccaaatggc atcgagtatt tcagactgca attgcgcgag ttccgggata tcgcgatcac
    19141 gacgtaacca tttaatatcc ggatggcgac gaatcacccc cgttgctgaa caaggcgcat
    19201 ctaataaaat gcgatcaaac tgttgctcgc cacaccattg ggaagggttg cggccatcac
    19261 cttgtttcac ggtcgccttc ataccaaggc gttttaaatt gtcgtaaacg cgagagaggc
    19321 gctgctcatc aatatcgacc gccagaactt gcgcctctgg agcaacctca agaatatgcg
    19381 ttgttttacc gcctggggcg gcgcaaagat ccagaatgtg ttcaccattt tgtggagcaa
    19441 gccaggtcat gcaaccttgt gctgaagcat cctgaacggt aacccatcct tcttcaaaac
    19501 cgggtagcgc atgaacaggt gcaggtgttt ccagctgtac agcatcaggg taatccgcat
    19561 gcgggaaacc tttcattcct gcttcatcca gcaatgcaag ccagctgtcg cgggaatgat
    19621 gcgtacgatt aacgcgcagc cacattggcg gacgctggtt attggcttcg acgatggatt
    19681 gccactgctc gggatacgcc ttttgcagac gcttcagcaa ccaggaagga tgcagataac
    19741 gtgcatcact ggcattaaac tcggctaata actcatcttg ctgacgctgg aactgacgta
    19801 atacaccgtt aatcaatccc ttaagttgcg ggcgcttaat tgcaactgcg ccttcaaccg
    19861 tttcagccag cgcggcatga ggtggaatgc gggtataaag cagttgatac aaaccaacca
    19921 taatcaggta atgaacagta cgctgtttgc ctgtcatcgg acgggccatt agcttattaa
    19981 tcagccagtc taactgtgag agcgtacgca gtacgccaaa gcataactcc tggagaagag
    20041 ctttatcttt atcggaaact ttttgctgga gcggtggcag aatgttgctc agtgattgcc
    20101 cttgctcaac gacttgttca atggcctggg ccgccatgct acgtaaatta
//
LOCUS       DAFGPF010000087        19772 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFGPF010000087 DAFGPF010000000
VERSION     DAFGPF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19772
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.087"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            217..759
                     /locus_tag="LSX49_003565"
     CDS             217..759
                     /locus_tag="LSX49_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169927.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTEST
                     GLALSGNWTHNDDDGDAAGVGLGLNLPLGPLMATVGGKGVYTNPNDGDEGYAAAVGGG
                     LQWQIGDSFRLFGEYYYSPDSLSSGIKSYEEANAGARYTIMRPVSIEAGYRYLNLAGK
                     NGNRDNAIADGPYVGVNASF"
     gene            859..2061
                     /locus_tag="LSX49_003566"
     CDS             859..2061
                     /locus_tag="LSX49_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HBL7169928.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAIQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEEQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQSRQFSLTLSEQF
                     TGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGLEDEH
                     LNFALATPDGTFALRVHFSATRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     VESMTLSV"
     gene            2281..3063
                     /locus_tag="LSX49_003567"
     CDS             2281..3063
                     /locus_tag="LSX49_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBL7169929.1"
                     /translation="MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYL
                     LLNELRRQRFLSLDHQENFCLWTRLVELSGHALSKMDLRELARPRLTQLMDTTGLLCH
                     LGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
                     VWERATPTTITHPQRLYEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAIS
                     VVGTRLQINEEYRDYLAGKAIACARDISRLLGWKSPFDLQAS"
     gene            3078..4283
                     /gene="rhmD"
                     /locus_tag="LSX49_003568"
     CDS             3078..4283
                     /gene="rhmD"
                     /locus_tag="LSX49_003568"
                     /EC_number="4.2.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HBL7169930.1"
                     /translation="MTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATP
                     MSKYREYEQSRQSFGINVLGTLIVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEG
                     KCVSDIKLIHDQMLNATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAV
                     RDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFW
                     LMLDCWMSQDVNYATKLAHACAPYNLKWIEECLPPQQYEGYRELKHNAPAGMMVTSGE
                     HHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHA
                     VITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRD
                     CNLKRPYSH"
     gene            4340..5629
                     /locus_tag="LSX49_003569"
     CDS             4340..5629
                     /locus_tag="LSX49_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416749.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169931.1"
                     /translation="MSTALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQI
                     DTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWAD
                     TEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
                     GALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPGQARFLSKQEKTLLINQ
                     LASEEQQKVTSRLSDALRNGRVWQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFT
                     ASVVTAIPWVAALFGTWLIPRYSDKTGERRNVAALTLLAAGIGIGLSGLLSPVLAIVA
                     LCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFS
                     SDAAGLLTLAAVAVIGSLIIFTLRVNRTVAQTDVAHH"
     gene            5647..6450
                     /gene="yfaU"
                     /locus_tag="LSX49_003570"
     CDS             5647..6450
                     /gene="yfaU"
                     /locus_tag="LSX49_003570"
                     /EC_number="4.1.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-L-rhamnonate aldolase"
                     /protein_id="HBL7169932.1"
                     /translation="MNALLTNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLL
                     IDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTA
                     DQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDN
                     LDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAV
                     APDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRVKGSY"
     gene            complement(6491..6724)
                     /locus_tag="LSX49_003571"
                     /pseudo
     CDS             complement(6491..6724)
                     /locus_tag="LSX49_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6725..7720)
                     /locus_tag="LSX49_003572"
     CDS             complement(6725..7720)
                     /locus_tag="LSX49_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HBL7169933.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSEGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGEASPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRDFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIQEIAERSPLQKERLMTIAERLRQEGHQIGWQEGKIEGWQEGKLEGLQ
                     QGKLEGLQKGKLEGLQEGMHEQAIKIALRMLEQGFEREIVLAATQLTDADIPNCH"
     gene            complement(7913..9103)
                     /gene="glpC"
                     /locus_tag="LSX49_003573"
     CDS             complement(7913..9103)
                     /gene="glpC"
                     /locus_tag="LSX49_003573"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HBL7169934.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMDTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            complement(9100..10359)
                     /gene="glpB"
                     /locus_tag="LSX49_003574"
     CDS             complement(9100..10359)
                     /gene="glpB"
                     /locus_tag="LSX49_003574"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HBL7169935.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELDLKVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWHWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERDGIREPILGLD
                     VLQTATRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAGQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            complement(10349..11977)
                     /gene="glpA"
                     /locus_tag="LSX49_003575"
     CDS             complement(10349..11977)
                     /gene="glpA"
                     /locus_tag="LSX49_003575"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HBL7169936.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGAAVCGVRVRNHLTGEIQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYN
                     EIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            12250..13608
                     /gene="glpT"
                     /locus_tag="LSX49_003576"
     CDS             12250..13608
                     /gene="glpT"
                     /locus_tag="LSX49_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HBL7169937.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRN
                     GG"
     gene            13613..14689
                     /gene="glpQ"
                     /locus_tag="LSX49_003577"
     CDS             13613..14689
                     /gene="glpQ"
                     /locus_tag="LSX49_003577"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL7169938.1"
                     /translation="MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRI
                     KNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDVL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            14892..15542
                     /gene="inaA"
                     /locus_tag="LSX49_003578"
     CDS             14892..15542
                     /gene="inaA"
                     /locus_tag="LSX49_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HBL7169939.1"
                     /translation="MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYARHAVSPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIY
                     VKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(15596..15850)
                     /gene="yfaE"
                     /locus_tag="LSX49_003579"
     CDS             complement(15596..15850)
                     /gene="yfaE"
                     /locus_tag="LSX49_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HBL7169940.1"
                     /translation="MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(15850..16980)
                     /gene="nrdB"
                     /locus_tag="LSX49_003580"
     CDS             complement(15850..16980)
                     /gene="nrdB"
                     /locus_tag="LSX49_003580"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HBL7169941.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL"
     gene            complement(17069..19354)
                     /gene="nrdA"
                     /locus_tag="LSX49_003581"
     CDS             complement(17069..19354)
                     /gene="nrdA"
                     /locus_tag="LSX49_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HBL7169942.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
BASE COUNT         4555 a         4880 c         5363 g         4974 t
ORIGIN      
        1 gtgacagtaa tctcttttgc gatgataact acatttatta ttatttttgt gtgtatcgat
       61 aaagtgtgtt tattttttcg gcgtttaatt atttaagaag tatttagtta caataagtga
      121 ctagatccct tttttcgctc attgaatcct ctgcgccagg cagtacaatc ccgcagcttt
      181 gggaattttg attaattgct tgtgggaaag aggataatga aaaaaattgc gctagcaggt
      241 ctggccggaa tgctgttggt ttctgcatcg gtcaatgcaa tgagcatcag cggccaggcg
      301 ggtaaagaat acaccaatat tggtgtcggt tttgggactg aatcgacggg cctggcgtta
      361 agcggtaact ggacacataa cgacgacgac ggtgatgccg cgggcgtggg gctggggttg
      421 aatctgcctc tcgggccatt aatggcgacc gttggcggaa aaggcgttta caccaacccg
      481 aacgatggtg atgaaggtta tgcagcggca gttggcggtg gtttgcagtg gcaaattggt
      541 gacagcttcc gcttgtttgg tgagtattac tactctccgg attcgctctc cagcggaatt
      601 aaaagttatg aagaagcgaa tgctggcgcg cgttacacca ttatgcgtcc agtcagcatt
      661 gaggctggct accgttacct gaacctggca ggtaaaaatg gcaatcgtga taacgccatt
      721 gctgatggtc cgtatgttgg ggtaaatgcc agcttctgac gccttccggc gcggcgttct
      781 gtcgcgccat tcagtttctt actacgccct gtctcccttt gcgttatagt gattcgataa
      841 caaaagcagg agataaccat gttaaaagtg gaaatgttat ccaccgggga tgaagtgtta
      901 cacgggcaaa tcgttgacac taacgctgcc tggctggccg attttttctt tcatcagggg
      961 ctgccattat ctcgccgcaa tacggtgggg gataaccttg atgacttagt caccattctt
     1021 cgcgaacgta gtcagcacgc cgatgtgttg atcgttaacg gcgggctggg accgaccagt
     1081 gatgatttaa gcgcactcgc cgctgcgaca gcaaaaggtg aaggcctggt gctgcatgaa
     1141 gcctggctca aagagatgga acgctatttc catgaacggg gacgagtaat ggcaccgagc
     1201 aaccgtaaac aagcggagct gcctgccagt gctgaattta tcaataaccc ggtaggcact
     1261 gcctgtggtt ttgccataca gcttaatcgt tgcctgatgt tctttacccc cggcgtaccg
     1321 tcagaattta aggtgatggt cgagcacgaa atcctgccgc gcctgcgcga gcgtttttct
     1381 ttaccacagc cgccggtttg cctgcgtttg actacctttg gtcgttcgga aagcgatctg
     1441 gcacaaagcc tggacactct acaactgccg ccgggcgtaa caatgggcta tcgctcctca
     1501 atgccgatta tcgaactgaa actcaccgga ccggcaagcg aggaacaggc gatggaaaaa
     1561 ctgtggctgg acgttaaacg tgttgccgga cagagcgtga ttttcgaagg caccgaagga
     1621 ctgcccgcgc agatcagtcg cgaattgcag agccgccagt tcagcctgac gctgagcgag
     1681 caattcaccg gtggtttatt ggctttgcaa ctttctcgcg caggtgctcc attgctggcg
     1741 tgtgaagtgg ttccttcaca ggaggaaacc ctggcgcaaa ctgcgcactg gattacagaa
     1801 cggcgggcga accattttgc tgggttggca ctggctgttt ctggtctgga agatgagcat
     1861 ctcaactttg cactagccac gccagacggc actttcgctt tgcgtgtaca tttcagtgcc
     1921 acacgctaca gtctggctat tcgccaggaa gtgtgcgcaa tgatggcgct taatatgcta
     1981 cgccgttggt taaacggcca ggacatcgcc agcgagcatg gctggattga ggttgttgag
     2041 tccatgacct tatctgtctg attccgccac tctgtgccgg tttactgcac cggcacattc
     2101 cccctccggc aaaatttgtc caacctgttg tactcaataa gaaaaaatcc gtgcgctgat
     2161 tcacaaattt gtgcgtaatt tctccagtcc gctggacgag aaacgggatt tgatgcgctt
     2221 cacaatttta ctccccctga acaacgagac tgattccagt atctaagact ggagtccagt
     2281 atgttggaat caagcaaagt tcccgccctg acacgggcta ttgatattct caatttgatt
     2341 gcccggattg gcccctgtag tgctgcgacg atcattgaca cattggggat ccctaaaagc
     2401 acagcctatt tgctgcttaa tgaactcagg cgtcagcgtt ttcttagcct tgatcaccag
     2461 gaaaattttt gtttgtggac caggctggtg gagctttccg gtcatgcgtt aagcaagatg
     2521 gatctccggg aactggctcg accgcgtttg acgcaactga tggataccac cgggctgtta
     2581 tgtcacctgg ggattattga taacggcagc gcttattaca ttttgaaagt ggagtcatca
     2641 gccactatca gcgtgcgttc ccatgaagga aaaagccttt cgctttatcg ctccggaata
     2701 ggtaaatgcc tgcttgcctg gcaacctgca gctgtacagc aaagtattat cgaagggctg
     2761 gtctgggaac gggcgacacc cacaacgatt actcatccac aacggctcta cgaagaactg
     2821 gcgcgtattc gccgccaggg ctggagctat gacaacggcg aagattacgc cgatgtccgt
     2881 tgtgtcgctg cgccggtgtt taacgccaat aacgagctta ccgctgcgat ttcggtggtc
     2941 ggtacccgct tacaaatcaa tgaagaatac cgtgattatc tggcgggcaa ggccattgcc
     3001 tgtgccaggg atatttcacg tttgttggga tggaaaagtc cctttgactt acaggcctca
     3061 taacaatgga gaacatcatg accctaccaa aaatcaaaca ggttcgcgcc tggtttactg
     3121 gcggtgcgac agcagaaaaa ggcgctggcg gcggtgatta tcacgaccag ggggcgaatc
     3181 actggattga tgatcatatt gccaccccga tgagtaaata ccgcgaatac gagcagtccc
     3241 gccagtcatt tggcattaac gttcttggca cgttgattgt tgaagttgaa gcagaaaacg
     3301 gccagaccgg attcgctgtt tcgacagccg gtgaaatggg ctgttttatt gtcgaaaaac
     3361 atcttaaccg tttcattgag ggtaaatgcg tcagtgatat caaactgatc cacgatcaaa
     3421 tgctcaatgc caccctgtat tactccggct ctggtggcct ggtgatgaat acgatttcct
     3481 gtgtcgatct ggctctgtgg gatctgttcg gcaaagtggt cgggcttccg gtttataaac
     3541 ttttaggcgg cgctgttcgt gatgagattc agttctacgc cacaggtgcg cgtccggatc
     3601 tggcaaaaga gatgggcttt atcggtggca aaatgccgac gcactggggg ccacatgatg
     3661 gcgatgcggg gatccgcaaa gatgccgcta tggtcgcgga tatgcgtgaa aaatgcggtg
     3721 aggatttctg gttaatgctc gactgctgga tgagtcagga cgtgaattat gccaccaaac
     3781 tggcccacgc ttgcgcgccc tataacctga aatggatcga agagtgcctg ccgccacagc
     3841 agtatgaagg ttatcgcgaa ctgaaacaca acgcaccagc ggggatgatg gtcaccagcg
     3901 gtgagcacca cggcacactg caatctttcc gtacgctttc agaaaccggt atcgacatta
     3961 tgcagccgga tgttggctgg tgcggtggct taaccacgct ggtggaaatt gccgcaatcg
     4021 ccaaatccag ggggcaactg gtggtgccac acggttcgtc tgtttactcc caccatgcgg
     4081 tgatcacctt caccaatacg ccattcagcg aattcctgat gaccagcccg gattgttcaa
     4141 cgatgcgtcc gcaatttgat ccgattctgc ttaatgagcc agtaccggtg aatggtcgta
     4201 ttcataaatc agtgcttgat aaacccggtt tcggcgtcga actcaatcgt gactgcaatt
     4261 tgaaacgccc ctacagccac taatcactcc gggcgttgct gtgacaacgg taacgcccac
     4321 atattctaag gagcttttta tgagcaccgc tttgcttgac gccgtggtga agaaaaaccg
     4381 cgcgcgttta attccgttta tgttggcgct gtatgtgctg gcgtttctcg accgttcgaa
     4441 tattggtttt gccaaacaga cctaccagat tgataccggg ctgagtaatg aagcttatgc
     4501 gctgggagca ggcattttct ttgtggtata cgcgtttctg ggggttccgg cgaatctttt
     4561 gatgcgcaaa ctgggggcca gaacctggat tggtacgaca acactgctgt ggggatttct
     4621 ttcggctgcc atggcatggg ccgatactga agcgaaattt ctgatcgttc gcactctgct
     4681 tggtgctgcg gaggccgggt ttttccctgg tatgatttat ctcacttcgc aatggtttcc
     4741 gcagcgtaat cgcgccagca ttatggggct gttctatatg ggcgcaccgc tggcgttaac
     4801 actgggatca ccgctttccg gcgcgctgct ggagatgcat ggatttatgg ggcatcccgg
     4861 ctggttctgg atgtttgtga ttgaaggatt gctggcagtc ggcgctgggg tattcacatt
     4921 cttttggctt gatgacacac cggggcaggc acgttttctg agtaaacaag aaaaaacgtt
     4981 gcttatcaat caactggcaa gtgaagaaca acagaaagtg acttctcgat tgagcgatgc
     5041 gctgcgtaat gggcgagtct ggcaactggc gattatctac ctgaccattc aagtggcggt
     5101 ttacggatta attttcttcc tgccgaccca ggttgctgca ttgctgggga caaaagtggg
     5161 ctttacggcg tcggtggtca ccgccattcc gtgggttgcg gccttgtttg ggacctggct
     5221 tattccgcgc tactccgata aaaccggcga acggcgtaat gtcgcagcgc tgacattact
     5281 ggcggcgggc attggtattg gtctctccgg gctgctttct ccagtactgg cgatcgtagc
     5341 actgtgtgtt gcagccatcg ggtttattgc cgtgcaaccg gtgttctgga cgatgccgac
     5401 acaacttctt tccggtacgg cgctggctgc ggggattggt tttgtaaacc tgtttggtgc
     5461 agtgggcggg tttattgccc cgatcctgcg cgtgaaagca gaaacgttat tttccagtga
     5521 tgcggcggga ttactgacgc tggcagcggt ggcggtcatc ggttcgctga ttattttcac
     5581 tctgcgtgta aatcgcactg ttgcgcagac cgacgtggca catcattaaa tagtttaagg
     5641 aacacgatga acgcattatt aaccaatccc tttaaagaac gtttacgcaa gggcgaagtg
     5701 caaattggtc tgtggttaag ctcaacgact gcctatatgg cagaaattgc cgccacttcc
     5761 ggttatgact ggttgctgat tgacggggag catgcgccaa acaccattca ggatctttat
     5821 caccagctac aggcggtagc gccctatgcc agccaacccg tgatccgtcc ggtggaaggc
     5881 agtaagccgc tgattaaaca agtcctggat attggcgcgc aaactctact gatcccgatg
     5941 gtcgatactg ccgatcaggc acgtcaggtg gtgtctgcca cgcgctatcc tccctacggt
     6001 gagcgtggtg ttggggccag tgtggcacgg gctgcgcgat ggggacgcat tgagaattac
     6061 atggcgcaag tcaacgattc gctttgtctg ttggtgcagg tggaaagtaa aacggcactg
     6121 gataacctgg acgaaatcct cgatgtcgaa gggattgatg gcgtgtttat tggacctgcg
     6181 gatctttctg cgtcgttggg ctacccggat aacgccgggc acccggaagt gcagcgaatt
     6241 attgaaacca gcattcggcg gatccgtgct gcgggtaaag cggctggttt tctggctgtg
     6301 gctcctgata tggcgcagca atgcctggcg tggggagcga actttgtcgc tgttggcgtt
     6361 gacacgatgc tctacagcga tgccctggat caacgactgg cgatgtttaa atcaggcaaa
     6421 aatgggccac gcgtaaaagg tagttattga tatcaaaggc ccatggggat cggctgtggg
     6481 cctgtgttaa ttagtggtta ttcgctgcca gatcggcttc gcttagctga gtggccgcga
     6541 gcacctgatc acgatcaatg ccctgttcca gcatgcgcaa agcaatttta atggcttgtt
     6601 catgcatgcc ttcctgcaaa ccttctaatt taccttcttg ccagccttca atcttaccct
     6661 cctgccagcc aatttgatgt ccttcctgcc gtagccgttc agcaatagtc atcaatctct
     6721 ccttttaatg acagttcgga atatcagcat cagtgagttg ggttgccgcc agcacaatct
     6781 cacgttcaaa gccctgctcc agcatgcgca aggcaatttt aatggcttgc tcatgcatgc
     6841 cttcctgcaa accttctaat ttacctttct gcaaaccctc caatttacct tgctgcaaac
     6901 cttctaattt accttcttgc cagccttcaa ttttaccttc ttgccagcca atttgatgtc
     6961 cttcctgccg tagccgttca gcaatagtca ttaatctctc cttttgtagt ggtgaacgtt
     7021 cggcaatctc ctgaataaag cgggtgaaac gggaggtatc gccgcattgc agcagataat
     7081 taaacagtgt ttgtagctgg ctgtcattag tgaagtctct aaccaaaagc gtggtgatcc
     7141 tgtcgaccat accgattaaa tcgcggtcgc gaatatgctt ttgaatcagt tccagcagag
     7201 ctatacgccg atgttgcatg atctcatcgt caggtacgat ggtgatatcc accaacggaa
     7261 aagcttcggt gtacaactgc cgggcaagtt gcggatcgtc aaactcatcc agccagttga
     7321 gtgagtacgg gtagggcgag gcttcgccat gataaaacag caatggcacc accagcggaa
     7381 ctctgtcata gcctttatcc aggtgacgct gcatggcggc agtggcatag cgcattagcc
     7441 gaaaagccat attcttttct gcagagcttt gatgttcaat cacgcagtag atatagccgt
     7501 caccctcgct ggtttccacg gaccacaaaa catccgagta gtaagcgcgt aaactttttt
     7561 caataaaact ggtgggttcc aggcgtaagg tttgcaggtt gcaaagcttg cgcagcggct
     7621 ctggtagatg tatttccaga aaatcccgtg cggtttcggg tgtgaacata aaggttttaa
     7681 acaccgcatc atgcggggag gaggttgttg attcggtcat ggttgtccgt cacctgatat
     7741 ttatgatgac gcgacattac ggttatccca ggcctttgat atctgccagt ttcagccttt
     7801 gcgagacgtt ttcagaggaa ttttcactgc gttgcaacgc atacattggg cacggaatcg
     7861 tgtacgcaaa aatgcccggt aacaacatgc ttaccgggca tcagaaagga gtttaagcca
     7921 acgcctgtgc cagcagcgta atcggatgtt cgcagcgaag acttgtggac atctcaatct
     7981 gccatttgca ggtttcgcag tcggtgacca ccagatctgc gccgctctct tctatctggc
     8041 ggaacagtgg tgcgccgatg gcttgtgaag tggggtagtt ctcttttttg aaaccgtaag
     8101 ttcccgcaat accgcagcac tgggaatcca gcaccgttaa ctcaagcccc gggattttac
     8161 gcaacagctc cagggtgtag agcgtccagc ccattttttc catatggcac ggagtgtgat
     8221 aaaccacttt cagcggcagc ggtttcagcg gtaacgtttt gccttcgtcc agcttgcgcc
     8281 acagccagcg ggtcgccagt tcgatatgat cgcgcaagcc tttgttgtcg acattcagca
     8341 cttctgggta ttcgtcgcgc agggcaaatg tacacgttga ggaggtggca atcaccggaa
     8401 tgccttttac tcccacagct tcgcggatcg actctacatt cgtaattgcc tgtttgcgtg
     8461 ctttatcggt aaaaccgttg gcgatcagcg gtacgccgca gcatttttct ttactgagca
     8521 gttgtacgcc ggtatccatc gcgttgagca ctttaattaa atctttgcct agttgcggat
     8581 ggttgtagtt aacgaagcag ccgtgaaaga aagcgacctg gtctttatac tgcgcttgct
     8641 gagccgccac gctgcgatac cagcgacgga acgtgccgaa ggagtatttc ggtagcgtgc
     8701 ggcgatgatc gatttttaac gccgcatcaa gcagctgacg caccggtttc agcgaggtag
     8761 cggtgttgac gatgggtgcg aacggcgtgg atacgctacc catcaggtcg gtatgactca
     8821 acacaaaatt acgcagcgac gggcgcgtgg tgtcatattt cgcccgcgcg cgctggataa
     8881 tatcgccaat cttcacatcg gacgggcagg cgacttcaca acgtttgcag ttgatgcaat
     8941 atttcagcgc ctcgtcatac agtgcgccat ctttcaaacg cagacgctcg ccatccggcc
     9001 cggcttgttt tggccccgga taacccggat tcacccggct caccgggcag gcggtggtgc
     9061 agacggtgca cttaatgcag ttttcgaagc tggtgtcgtt cattgttggc ctcctgcgcg
     9121 ttgggcaatc tgttgagcgg catgtaaagc actgacggca caaacaccgc cgccgcatcc
     9181 ctgggcgatg ggatcaaatc cgcccagcac cgaaccgatg gcaaacaggt tctcaatggt
     9241 ttgccctgcc tgcgacgggc gtagtgcctc atcagtggtt acaccgaact gctgccacgg
     9301 ctgcggcgca aaaaaatcgc ccttatacca ttcaccccgc gtagcggttt gtagcacatc
     9361 aaggccgaga atcggctcgc gaatgccgtc acgttccgct accagtccgc cgctaaagaa
     9421 actgccgctc gcaagcaccg caaatcgtgg gcgcagcggg atatcggcgt gattgcgcgt
     9481 ccagatttca ttcactacac catttttaca ggtcactttt ttcacttcat cgcccggcat
     9541 ccacacgccg ccctggcgca caaactggcg ctgtaactgg ttttgcagac gaatgcccag
     9601 cacggaaggc ggcagcgttg gcaaaagcat caatgaacaa ggtagttttt cattcaacca
     9661 atgccacagt ttgtcatcgg ccaggccgaa gcaggcgggc atcaggatca tttcgcaggt
     9721 attggcgacc ggaataagcg catcaagtaa caacggccag ttttcttcat tatcaaggaa
     9781 gcgggcaata ttcaccgccc ggaactcggt ggcgttattg cgcagcacat ccagttccgg
     9841 cagttcaatt tcagcggttt caactttaag atccaattcg cgcaatgaag ccgccgcaag
     9901 atgcgcctga aaatccatca ggccgctaat tcccactaca catattttct tcgcgggcag
     9961 cggccagaca gggacttctg gcgaacttag ccaggttgag cgcagagtgc cgagcggcgt
    10021 aatccgctgg tgagccagtt ctacgctgcc ctgcaattgc gcaccgcttt cagcgattaa
    10081 tgcctgcgcc tggcaagcga gatcgagcac gcgttgaggc ccgagaagag tgtaaggatg
    10141 ggcaggtgcc tgctgacgca aagattccag tccactgtga atgtctgtca ccggttgacc
    10201 atccggcaga tggctcagca aatccagcga tccagatgag aaatggagcg cgctttgacc
    10261 acgagtgaca atggcacagc gcaggccgtg tttttgcagt tgcaggccac agagtaatcc
    10321 ggcgaggccg ccgcccataa tgacagtatc aaagcgcatc tttctgctcc ttctccagac
    10381 cacacaatcc ctgataaacc cagcgggtaa attcgctttc gcgcagtgca tctccccagg
    10441 cgatgggttg cacgcctttc cagcgttcgt ttaggaaggt ggaaagttgc tcaatagatt
    10501 gcgcggacgt cgtgacgtta aaacgttgca gcagtccggc agcgcggcag gcgcagagct
    10561 cgccctggca ggtgcccatc cccacacggg tacgacggcg taaatccagc aggctattaa
    10621 cgtttaaatt ttctaccgcg tactgcactt cacccgcagt taccgcttcg cactcacata
    10681 ccaggctacg gtgcagacgg ccttcgctca gccaggcagg cgtgcgatcg ccatgacgat
    10741 aaaccgcaga accgcgcagc ggggcaggta gggagatgac tttacgcaag gtaacttcag
    10801 cgggttcctg tgaaccagga agtgccagat cggcggtcgt acaggggcgc gtgttgccca
    10861 gtttgcggca tacggcatcg gtagcccatt ccgccatcag ccgataggtc atcagtttgc
    10921 caccggtgat ggtgataaac ccgtccagac catcgcgttc agcatggtcg agcagcacga
    10981 tgccacggct gacgttacgt ccgctcggat cgtcatcgct ggcaaccagc gggcgtacgc
    11041 cagagtaggc ccgcaaaatg cgcgttttcg ccatcacggg ggccagtttt tccccttcac
    11101 gcagcagaat atcaacttct tctgccgtta ctcgattatc gtcaatctcg ttgtaatcaa
    11161 tacgtaaaga ggtggtgcca atcagcgaaa tggtatcgcc aggcaccaga atatcggcgt
    11221 cggaaggttt gcggcagcgg ttgatcacat gctgattaat gcggtgatcc atgatcagca
    11281 gcgatccttt cgccgggaac atgcgaatgc gcagatcggc atattcggca atgtgttgcc
    11341 cccagatccc ggcggcatta actacgacag gtgcatgaag tgcctgaatt tcgccggtga
    11401 gatggttacg tacacgaacg ccgcacaccg ccgcgccttc acgaatcagc cccgtgactt
    11461 catgagcggt aaggataacg gcaccgtgtt ctttggcatc cagcatgttt gctgctgtca
    11521 gacgaaatgg atcaacggtg ccatccggaa ctttcaccgc gccaatcagt gccgggttaa
    11581 cggcaggttc gataatgcgc gcttgctgcg gatcaatggc ttctgcgctg atccctgctt
    11641 cttcgcaggc gcggataaaa gtggcctgga aggagaggtc atcttccggc agggtgataa
    11701 acaggccgtt ggttggttct acgcagtgac gtgcaatgcg tttcaggatc tggttttcac
    11761 taatacattc gcgggccgat tccgcatcgg ttaccgcata gcgcgcaccg ctgtgcagca
    11821 ggccgtggtt acgcccggtg gcaccggttg cgatgtcgtg gcgctcaacc aaaatcacgc
    11881 gcagcccgcg cagggcacag tcgcgggcaa tcccggctcc cgttgcgcca ccgccaatga
    11941 taatcacgtc acttgattgc gagtcgcgag ttttcattgt tatccctcag aagttcgttt
    12001 tttaccattt agccatagta aaaacatgaa ttgtttgatt tcgcgcatat tcgctcataa
    12061 ttcgaaagtg aaacgtgatt tcatgcgtca ttctgaacat ttcaaccatc gtatttaata
    12121 atgtgtgcgg taattcacat ttaatttatg aatgttttct taacatcgcg gcaactcaag
    12181 aaacggcagg ttctcccact gaatcaggct gttaatcata aataagacca cgggccacgg
    12241 aggctatcaa tgttgagtat ttttaaacca gcgccacaca aagcgcgctt acctgccgcg
    12301 gagatcgatc cgacttatcg tcgattgcgc tggcaaattt tcctggggat attctttggc
    12361 tatgctgctt actatttggt tcgtaagaac tttgcgctcg ctatgcctta tctggttgag
    12421 cagggattct cacgcggtga tttaggtttt gccctttcgg ggatctcgat tgcttatgga
    12481 ttttcgaaat tcatcatggg ttcggtatcg gatcgctcga atccgcgcgt tttcctgccc
    12541 gcaggtttga ttctggcggc ggcagtgatg ttgtttatgg gctttgtgcc atgggcgacg
    12601 tcgagcattg cggtgatgtt tgtactgttg ttcctctgcg gttggttcca ggggatgggg
    12661 tggccgccgt gtggtcgtac tatggtgcac tggtggtcgc agaaagaacg tggcggtatt
    12721 gtgtcagtgt ggaactgtgc gcacaacgtc ggtggtggta ttccgccgct gctgttcctg
    12781 ctggggatgg cctggttcaa tgactggcac gcggcgctct atatgcccgc tttctgcgcc
    12841 attctggtgg cactgttcgc ctttgcgatg atgcgcgata ccccgcaatc ctgtggcctg
    12901 ccgccgattg aagagtacaa aaatgattat ccggacgact ataacgaaaa agcggaacag
    12961 gagctgaccg cgaagcagat cttcatgcag tacgtgctgc cgaacaaact gctgtggtat
    13021 atcgccatcg ccaacgtgtt cgtttatctg ctgcgttacg gcatcctcga ctggtcaccg
    13081 acttatctga aagaggttaa gcatttcgcg ctggataaat cctcctgggc ctactttctt
    13141 tatgaatatg caggtattcc gggcaccctg ctgtgcggct ggatgtcgga taaagtcttt
    13201 cgtggtaacc gtggggcaac cggcgtcttc tttatgacac tggtgaccat cgcgactatc
    13261 gtttactgga tgaacccggc aggtaaccca accgtcgata tgatttgtat gattgttatc
    13321 ggcttcctga tctatggccc tgtgatgctg atcggtctac atgcgctgga actggcaccg
    13381 aaaaaagcgg caggtacggc agcgggtttt accgggctgt ttggttacct gggcggttcg
    13441 gtggcggcga gcgcgattgt tggctacacc gtggacttct tcggctggga tggcggcttt
    13501 atggtaatga ttggcggcag cattctggcg gttatcttgt tgattgttgt gatgattggc
    13561 gaaaaacgtc gccatgaaca attactgcaa aaacgcaacg gaggctaatg gcatgaaatt
    13621 gacgctgaaa aaccttagca tggcgatcat gatgagcact atagtcatgg gaagcagtgc
    13681 aatggcggcg gacagcaacg aaaaaatagt catcgcccat cgcggtgcca gtggatattt
    13741 gccggagcat acgctgccag caaaagcgat ggcgtatgcg cagggagcgg attatctgga
    13801 acaggatttg gtgatgacca aagacgacca tctggttgtt ctgcatgacc attatctcga
    13861 tcgtgttact gatgttgccg atcgtttccc ggatcgggcg cgcaaagacg gtcgttacta
    13921 cgcgatagat ttcacgctgg atgaaattaa gtcgctgaaa tttaccgaag gtttcgatat
    13981 tgaaaacggt aaaaaagtgc agacttatcc ggggcgtttc ccaatgggta aatctgactt
    14041 ccgggtgcac acctttgaag aagagattga atttgttcag gggttaaacc actctaccgg
    14101 gaaaaatatc ggtatctatc cagaaattaa agcgccgtgg ttccatcatc aggaagggaa
    14161 ggatattgcg gcaaaaacgc tggaagtgct gaagaaatat ggttacaccg gtaaggacga
    14221 caaagtttat ttgcaatgtt ttgatgctga tgagctgaag cgtattaaga atgagctgga
    14281 acctaaaatg ggtatggatc tcaatctggt acagctgatt gcctataccg actggaatga
    14341 aacgcagcag aaacagccgg acggaagctg ggttaattac aattacgact ggatgtttaa
    14401 gccgggtgcc atgaaacagg tggcggaata tgctgatggt attggtccgg attaccatat
    14461 gttgattgag gagacatcgc agccgggtaa tatcaaactc actggcatgg tgcaagatgc
    14521 tcagcagaat aaactggtag tgcatcctta taccgtgcgg tcagataaac tgcctgaata
    14581 cactactgat gtgaatcagt tatatgatgt tctgtataac aaagcgggtg taaatgggct
    14641 atttactgac ttccctgata aggcagtaaa attccttaat aaagagtaaa ttaactaccg
    14701 gatggcactt atgtgctatc cgataccact cttcattaaa gtctgtgggt tatccttaat
    14761 tgcaattatt tagagcgaga tgacttgttc ccggcataag atactcgtca atacaacacg
    14821 tattattaag attttcctca gctaaacatc tatagtcatt gtcgttaata aaaaacgaca
    14881 ggcgataggg tatggcagtt tcagcaaaac acgacgaatt taatcactgg tgggcaacag
    14941 agggcgactg ggttgaagag cctaactatc gccgtaatgg tatgagcggg gtgcaatgcg
    15001 tcgagcgcaa cggcaaaaag ctgtatgtaa agcgcatgac gcatcatctg tttcattccg
    15061 tacgttatcc gttcggccga ccaacgattg tccgtgaggt tgcggtaatt aaagaactgg
    15121 aacgggccgg tgtcatcgtg ccgaagattg tttttggtga agcggtgaaa attgagggtg
    15181 aatggcgcgc gttgctggtg actgaagata tggcggggtt catcagcatt gctgactggt
    15241 atgcccggca tgcagtatcg ccttattctg acgaagtacg gcaagccatg ttgaaagcag
    15301 tggcgctggc gtttaagaaa atgcatagcg ttaatcgtca gcatggctgt tgttatgttc
    15361 gccatatcta tgtgaaaaca gaaggtaagg cagaagctgg atttcttgac ctggagaaaa
    15421 gtcgtcgccg cttgcgtcgt gataaagcga ttaatcatga cttccgccag ctggaaaaat
    15481 atctggagcc gatccccaaa gcggactggg agcaggtgaa agcatattac tacgctatgt
    15541 aatcgttgta ggccagataa gacgtataag cgtcgtatct ggcgttaaaa ccaattcaca
    15601 tctcgatttc aatatcgcct tttgcccggc aacaacaggg caaaatttcc cccggctgaa
    15661 taaaagctaa cggttcggca atccagtcca cctggcctgc gaccagtcgg gtgcgacagg
    15721 agccgcagta accttcgcgg cactggtact caaccgccac attgtgggat tccagcgccg
    15781 ccagaaggga agggtgttca tcctggcaca gcagttgtgt gccagtaatg cgcagggtaa
    15841 cgcgggccat cagagctgga agttactcaa atcgtcggtg tccacttccg cgtcaatctg
    15901 cccgaccaga taagaactga cttccacttc ctgcggagca acctgcacgt tatcagacac
    15961 cagccaggtg ttgatccacg ggatcgggtt ggagcgcgtc tggaacggca gatccaaacc
    16021 gactgcctgc atacggatat tggtgatgta ttcaacgtac tggcagagaa tgtctttatt
    16081 cagaccaatc atcgaaccat cacggaacag ataatccgcc cagtctttct cttgctgtgc
    16141 cgcctggaca aacaggtcat agcactcctg cttacattct tcggcaattt ccgccatctc
    16201 cggatcatcc gcgccgctgc gcagcagatt cagcatatgc tgggtgccgg tcaggtgcag
    16261 ggcttcgtcg cgggcaatca ggcgaataat tttggcgtta ccttccatca gctcacgttc
    16321 agcgaatgcg aaagagcagg caaagctgac gtagaagcgg atcgcttcca gcgcgttaac
    16381 gctcatcagg cagagataca gttttttctt cagctcgcgc aggctaacgg ttacggtttt
    16441 accgttaacg gtgtgggtgc cttcgcccag cagatgccag tagctggtca tttcgatcag
    16501 ttcatcgtaa tagctggaga tcccctccgc acgtttctgg atctgctcgt tggtaacgat
    16561 atcgtcaaag acaacagacg gatcgttaac gatattacgg atgatatggg tataggagcg
    16621 ggaatgaatc gtttctgaga acgcccaggt ttctacccag gtttccagtt ccgggatcga
    16681 gatcagcggc agcagtgcca cgttcggact gcgaccctga atggaatcca gcagcgtctg
    16741 atatttcagg ttgctgataa agatgtgttt ttcgtgttca ggcagtgcct ggtaatcgat
    16801 acggtcgcgg gagacgtcaa cttcttccgg acgccagaag aaagagagct gcttttcgat
    16861 cagcttttcg aagatgtcat atttttgctg atcgtagcga gccacgttga ccggctgacc
    16921 aaagaacatt ggttctttga gctgatcatt tttcgtctgt gaaaaggtgg tatatgccat
    16981 gaatgtgtcc tgtggtttta ttacccctca cccgtcccct ctcccgcaag gggagagggg
    17041 acggtttggt gcaaagactg ggggattatc agatcttaca tgcgccgctt tcgcagccat
    17101 cgtcctggat tgacggcacc agatcgtcct gcgcgtcttc tgcgccgtca cgggtgttct
    17161 gataatacag cgttttgacc ccgaatttgt aggcagtgag caggtctttc agcaactgct
    17221 gcatcggcac ttttcctgac gggaaacgtg acggatcgta gttggtgtta gcagagatcg
    17281 actgatcgat aaatttctgc atgataccca ccagttgcag gtagccatcg ttacccggca
    17341 tttcccacaa cagctcatag gcgtcgtgca gatgctcgta gtccggcacc acctggcgca
    17401 gaataccgtc tttcgacgct ttgatgctga cgtaaccgcg cggcggttca ataccgttag
    17461 tggcgttaga gatctgcgaa gaagtctcgg acggcatcag ggcagaaagc gtggagttac
    17521 gcaggccgtg cgttttgatt gactcacgca gtgcttccca gtcgtaatgc agcggctcat
    17581 tagcgatggc atccagatct ttcttatagg tatcgatcgg caggatccct ttcgcgtatg
    17641 tggtttcgtt aaaccacggg cacgcgcctt gctctttcgc cagctcatta gacgctttca
    17701 gcaggtaata ctgaatggct tcgaaggttt tatgcgtcag gttgttggcg ctgccgtcgg
    17761 agtagcgttt accgtgcttc gccaggtagt aagcgaagtt gatcacacca atacccagcg
    17821 tacgacgacc catcgctcca cgtttggcgg ccgggatcgg gtaatcctga taatccagca
    17881 gcgcgtcgag tgcgcgtact gccagaattg ccagctcttc cagttcatcc aggctgttaa
    17941 ttgcgcccag gttgaaagca gacagcgtac acagtgcgat ttcaccgttc tcgtcgttga
    18001 cgtcgttcag cggtttggtc ggcagggcga tttccaggca caggttagac tggcgcactg
    18061 gcgcgatggc cggatcaaac gggctatggg tattgcagtg gtcaacgttc tgaatataga
    18121 tacgaccggt agacgcacgt tcctgcatca tcagcgagaa cagctcaacg gctttcacac
    18181 gctgcttgcg gatgctgtcg tctttctcat atttggtata cagacgttca aactcttcct
    18241 gatcggcgaa gaacgcgtcg tacagccccg gtacgtcgga cgggctgaac agagtgatat
    18301 cttcaccttt cagcagacgg gtatacatca gtttgttgat ttgaaccccg tagtccatat
    18361 gacgcacgcg gttgccttcc acaccacggt tgtttttcaa caccagcagg ctttccactt
    18421 ccagatgcca catcgggtag aacagcgttg ccgcaccgcc gcgcacaccg ccctgagagc
    18481 aggatttcac cgctgtctgg aaatgtttgt agaacggaat acaaccggta tggaacgctt
    18541 cgccaccgcg aatcgggcta cccagcgcac gaatacgccc ggcgttgatg ccgatcccgg
    18601 cacgctggga aacgtattta acaatcgcgc tggaggtggc gttaatggaa tccaggctgt
    18661 cgccgcactc gatcagcacg catgagctga actgacgagt cggggtacgc acgccggaca
    18721 tgattggcgt cggcagcgaa attttaaatg tggaaaccgc gtcgtaaaaa cgcttcacgt
    18781 attgcaggcg cgtttcacgc gggtagttcg agaacaggca cgcggcaacc agaatataaa
    18841 ggaactgggc gctttcgtag atttcgccgg tcacgcggtt ctgtaccaga tatttgcctt
    18901 ccagctgctt aacggcagca taagagaagg tcatatcacg gtcgtgatcg ataaacgtgt
    18961 ccatctgctt gaactcttct tccgtgtagt cttccagcag atgattatcg tatttgccca
    19021 tctcgaccat tttcaccaca tggtcgtaca gcgcaggcgg ctcaaactga ccgtaggctt
    19081 ttttacgcag gtggaagatc gccagacgtg cggcgagata ctgataatcc ggcgcatcac
    19141 gggagatcag gtctgcggca gccttgataa tggtttcgtg gatgtcagag gtcttgatac
    19201 cgtcataaaa ctgaatgtgg gagcgcagct cgacctggga aatcgaaacg ttatgcagtc
    19261 cttctgccgc ccaatccaga acgcgatgga ttttgtcgag attgatgcgc tctgtgctac
    19321 cgtcgcgctt tgtcaccagc agattctgat tcatgtatgt cgtacctgtt tttcaatagc
    19381 ttcatgcaga ctacctgtag tgagggaagc tgctaagaac actatatata gggggtatgt
    19441 ttgggattca ctgcaagata gtgtgaaact ggccctcttg caagtgcata actttgtgga
    19501 taactcagga aggaaaaagt ggcttccgcg caccttaggt cagacaaggt gtccgggaaa
    19561 gtcaatggga agagaaaaat ttgttaaaaa taaccgttcg gtgaattctt gaacggtaaa
    19621 ataggatagg taaattgata tagatggttt attaatcttg ttgctaatga ttgccaaaat
    19681 tgatctaggc acaagtcgtc acataatctg atgtatctgt tgtggtcaat atataagcga
    19741 atgtaagcga ttgttgagtc ggaaatggtt gt
//
LOCUS       DAFGPF010000088        19604 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFGPF010000088 DAFGPF010000000
VERSION     DAFGPF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19604
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.088"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            525..1592
                     /locus_tag="LSX49_003582"
     CDS             525..1592
                     /locus_tag="LSX49_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBL7169943.1"
                     /translation="MDKSKRHLAWWGVGALAVAAVVAWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRLEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHTRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPDDLVVRLPQ"
     gene            1589..4324
                     /gene="rbbA"
                     /locus_tag="LSX49_003583"
     CDS             1589..4324
                     /gene="rbbA"
                     /locus_tag="LSX49_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HBL7169944.1"
                     /translation="MMHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGGVMVLGGDMRDPKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDVLPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVVHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCALSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG"
     gene            4324..5448
                     /locus_tag="LSX49_003584"
     CDS             4324..5448
                     /locus_tag="LSX49_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7169945.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKVWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLIAIGGAFFTIALLRFRKTIGTMA"
     gene            complement(5557..6408)
                     /locus_tag="LSX49_003585"
     CDS             complement(5557..6408)
                     /locus_tag="LSX49_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase"
                     /protein_id="HBL7169946.1"
                     /translation="MPLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLP
                     NFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLHLDHGKTQEDVKQAVRAGFTSVM
                     IDGAAFSFEENIAFTQEAVDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKT
                     FVERTGCDMLAVSIGNVHGLDDIPRIDIPLLKRIAEVSPVPLVIHGGSGIAPEILRSF
                     VNYRVAKVNIASDLRKAFITAVGKAYVNNHNEANLARVMASAKNAVEEDVYSKILMMN
                     EGHRSVK"
     gene            complement(6440..6709)
                     /locus_tag="LSX49_003586"
     CDS             complement(6440..6709)
                     /locus_tag="LSX49_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBL7169947.1"
                     /translation="MLTKTVEVRNSTGLHARPAACLAKAAKKCSCKVTLHYEGNDINA
                     TSMMNIMRAGIKGGKTVEIRCDGDDENEAIQTLTALFRDRFGEAE"
     gene            complement(6699..8207)
                     /locus_tag="LSX49_003587"
     CDS             complement(6699..8207)
                     /locus_tag="LSX49_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBL7169948.1"
                     /translation="MPDNSAAIVIDIGTTNCKVTCFSCLDATTLGAHKFVTAKQISPQ
                     GDVDFDIDALWQEVRQAIAQLNAASPLPVRRISIASFGESGVFLDEHGEILTPMLAWY
                     DRRGEEYLATLSEADSAALYDICGLPLHSNYSAFKMRWLLEHYPLRNRRGLRWLHAPE
                     VLLWRLTGEQRTDITLASRTLCLDVRKGEWSAKATALLHVPCSAFAPLVQPGEHAGWV
                     SESLCKTLGFSQPVSVTLAGHDHMVGARALQMMPGDILNSTGTTEGILQLDTQPTLDE
                     QAKRDKLANGCYSLANQFTLFASLPVGGFALEWLRNTFRLTDEEIAASLNRGYADYLA
                     GNWSLDDIPVFIPHLRGSGSPYKNRHTRGLFYGLGDTLNIDMLISSVSLGLTMEFANC
                     FACFNVPGTSVLKVIGPATHNPLWLQLKADILQRPVEAIAFSEAVSVGALLTAAPDIP
                     PPQVTIAQRLLPNRARYHQLQRYQHKWKSWYQLKLQQEGVMPLHHREEHYVD"
     gene            complement(8200..9558)
                     /locus_tag="LSX49_003588"
     CDS             complement(8200..9558)
                     /locus_tag="LSX49_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL7169949.1"
                     /translation="MNDIAHTLYNIVQYILGFGPTVMLPLVLFILALFFKVKPAKALR
                     SSLTVGIGFVGIYAIFDILTSNVGPAAQAMVERTGINLPVVDLGWPPLSAITWGSPIA
                     PFVIPLTILINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSSGSLFFGLLAAAIAA
                     VVVLKLADWSAPLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPE
                     TVQKKFGIFGEPMMVGTILGIFLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEG
                     LLPLSEAIKKYLNAKYPDRDDLYIGLDIAVAVGNPAIISTALLLTPISVFIAFVLPGN
                     EVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAKDV
                     NFKFAEGSSGQVSSFLDGGNPFRFWLLEIFNGNLIAIALVPVIALVLYGIFRMTRSTV
                     YA"
     gene            complement(9635..9916)
                     /locus_tag="LSX49_003589"
     CDS             complement(9635..9916)
                     /locus_tag="LSX49_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL7169950.1"
                     /translation="MSQTILFVCATGIATSTAVTEKVMEYCKEHGLNVNYSQTNVASL
                     PGNTDGVALVVSTTKVPYELDVPVVNGLPIITGIGEEKVLAQIVSILKK"
     gene            complement(9913..10386)
                     /locus_tag="LSX49_003590"
     CDS             complement(9913..10386)
                     /locus_tag="LSX49_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL7169951.1"
                     /translation="MQGIQFQENFIQRLPAGLSVEQIIRQLAQPLVTAELVVPDFADH
                     VLEREATYPTGLPTEPPCVAIPHTDHKHVRHNAIAVGILPEPVVFADMGGDPDPVPVR
                     VIFLLALGESNKQLNALGWIMEMIQDTPFMCALLTMETTEIHTAILNKMKERGEI"
     gene            complement(10411..11157)
                     /locus_tag="LSX49_003591"
     CDS             complement(10411..11157)
                     /locus_tag="LSX49_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL7169952.1"
                     /translation="MKSLSKSSQIPLYQQVVEWIRESIYTGDLVEDDRIPSEYQIMDM
                     LEVSRGTVKKAVAQLVKEGVLIQVQGKGTFVKKENVAYPLGEGLLSFAESLESQKIHF
                     TTEVITSRIEPANRYVAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCPGIV
                     EIDFNQHNLFPTIESLSQRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFF
                     SRGLPVEFGNVWLKGNKYYLGTVLQRREVS"
     gene            complement(11356..11757)
                     /gene="nikR"
                     /locus_tag="LSX49_003592"
     CDS             complement(11356..11757)
                     /gene="nikR"
                     /locus_tag="LSX49_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HBL7169953.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(11763..12569)
                     /gene="nikE"
                     /locus_tag="LSX49_003593"
     CDS             complement(11763..12569)
                     /gene="nikE"
                     /locus_tag="LSX49_003593"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HBL7169954.1"
                     /translation="MTLLNVSDLSHHYAHGGFSGKHQHQAVLNNVSLALKSGETVALL
                     GRSGCGKSTLARLLVGLESPSQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKAEQLARTSEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGDKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV"
     gene            complement(12566..13330)
                     /gene="nikD"
                     /locus_tag="LSX49_003594"
     CDS             complement(12566..13330)
                     /gene="nikD"
                     /locus_tag="LSX49_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HBL7169955.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSHGK
                     IVEQGDVETLFNAPKHAVTRSLVSAHLALYGMELAS"
     gene            complement(13330..14163)
                     /gene="nikC"
                     /locus_tag="LSX49_003595"
     CDS             complement(13330..14163)
                     /gene="nikC"
                     /locus_tag="LSX49_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HBL7169956.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLIIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFIDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            complement(14160..15104)
                     /gene="nikB"
                     /locus_tag="LSX49_003596"
     CDS             complement(14160..15104)
                     /gene="nikB"
                     /locus_tag="LSX49_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HBL7169957.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLNFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            complement(15104..16678)
                     /gene="nikA"
                     /locus_tag="LSX49_003597"
     CDS             complement(15104..16678)
                     /gene="nikA"
                     /locus_tag="LSX49_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HBL7169958.1"
                     /translation="MFSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKNELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWVLQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPRQYDP
                     QKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     SLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            complement(16789..17376)
                     /gene="acpT"
                     /locus_tag="LSX49_003598"
     CDS             complement(16789..17376)
                     /gene="acpT"
                     /locus_tag="LSX49_003598"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HBL7169959.1"
                     /translation="MYRIVLGKVSTLSAAPLPLGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPETPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYNSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            complement(17431..18480)
                     /locus_tag="LSX49_003599"
     CDS             complement(17431..18480)
                     /locus_tag="LSX49_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL7169960.1"
                     /translation="METPQPDKTGMRILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERILQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGIYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            18579..>19604
                     /locus_tag="LSX49_003600"
     CDS             18579..>19604
                     /locus_tag="LSX49_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312349.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7169961.1"
                     /translation="MKHCCKNVVILMPEPVAEPALNGLRLNLRIVSIVMFNFASYLTI
                     GLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADLLGPKKIVVFGLC
                     GCFMSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIG
                     RVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASK
                     GKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFV
                     GTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFP
                     ALGVVAVK"
BASE COUNT         4551 a         5152 c         5338 g         4563 t
ORIGIN      
        1 ttattttgtt gttttaaatg aatcttttag ggactatttt attaaaccca cgagccttta
       61 tcatctatca ttcttttcag aataaattat tttatattcg gtatttattc gcacatcaga
      121 cgataataac gctatgtgat agtcatcagg tttccctgtt acggaaacct gtgcaacaga
      181 atctgtgaac ctgtacagaa tatttttgga aaaaacacca gcgaacggaa gaacatcgcg
      241 atgtatcaca agttgatggc aatcaaatag acaacatgaa tataactgtt agtatttaat
      301 tgatttcact tatgagtatg cgtgtttcat ttacggccag gaatgctgat gatgacaaca
      361 ttactacccg ttttcactaa gccttcccca ttggcgctca atgctctgtg cgctggtcgt
      421 atttgccatt tccttcttat cccggatgga agaatccgct gaacgtcgtt cggtggcagt
      481 tgtaacacgt gtcgattgct tacagggatt atggcgggtc gattatggat aagagtaagc
      541 gccatctggc gtggtggggt gtcggggcac tggcggtggc tgccgtcgtg gcgtggtggc
      601 tgttgcgccc ggcgggtgtg ccggaaggct ttgctgtcag caatgggcgc attgaagcga
      661 cggaagtgga tatcgccagc aaaattgccg ggcgtatcga caccattctg gtgaaagaag
      721 gccagtttgt tcgagaaggt gaagtgctgg cgaagatgga tactcgcgtg ttgcaggaac
      781 agcgactgga agccatcgcg caaatcaaag aagcacaaag tgccgttgcc gccgcgcagg
      841 ctttgctgga gcaacgccaa agcgaaactc gtgccgcaca gtcgctggtt aatcaacgcc
      901 aggcagaact ggactccgta gcaaaacgtc atacgcgttc ccgctcactg gcacaacggg
      961 gggcaatttc tgcgcaacag ttggatgacg accgcgccgc cgctgagagc gcccgagctg
     1021 cgctggaatc ggcaaaagct caggtttctg cttctaaagc cgctatagag gcggcgcgca
     1081 ccaatatcat tcaggcgcaa actcgcgtcg aagcggcaca agccactgaa cggcgcattg
     1141 ccgcagatat cgatgacagc gaactgaaag ccccgcgtga cggacgcgtg cagtatcggg
     1201 ttgccgagcc aggcgaagtg ctggcagcag gcggtcgggt gctgaatatg gtcgatctca
     1261 gcgacgtcta tatgaccttc tttctgccaa ccgaacaggc gggcacgctg aaactgggcg
     1321 gtgaagcacg tttgattctt gatgctgcac cagatctgcg tattcccgcg accatcagtt
     1381 ttgtcgccag cgtcgcccag ttcacgccaa aaactgtcga aaccagcgat gagcggctga
     1441 aattgatgtt ccgtgtcaaa gcgcgtatcc caccggaatt actccagcag catctggaat
     1501 atgtcaaaac cggattgccg ggcgtagcgt gggtgcgggt gaatgaagaa cttccgtggc
     1561 ctgacgacct ggtggtgagg ttgccgcaat gatgcatctg gaactggttc ccgtcccgcc
     1621 tgtcgcgcaa ctggcgggcg tgagccagca ttatggaaaa accgttgcgc tgaacaatat
     1681 cacactcgat attccggccc gttgcatggt cgggctgatt ggaccggatg gtgtcggtaa
     1741 atcgagcttg ttgtcgttga tttccggtgc tcgcgtcatt gagcagggcg gcgtgatggt
     1801 gctgggcggc gatatgcgcg acccgaagca tcgccgcgac gtctgcccgc gcatcgcctg
     1861 gatgccgcag gggctgggca aaaatctcta ccacaccttg tcggtgtatg aaaacgtcga
     1921 ttttttcgcc cgcctgttcg gtcacgacaa agcggagcgg gaagtgcgaa ttaatgagct
     1981 gctgaccagc accggattag caccgtttcg cgatcgtccg gcagggaaac tctccggcgg
     2041 gatgaagcaa aaacttgggc tgtgctgtgc gttaatccac gacccggaat tgttgattct
     2101 tgatgagcca acaacggggg ttgacccgct ctctcgcgcc cagttctggg atctgatcga
     2161 cagtattcgc cagcggcaga gcaatatgag cgtgctggtt gccaccgcct acatggaaga
     2221 ggccgaacgc ttcgactggc tggtagcgat gaatgccgga gaagtgctgg caaccggtag
     2281 cgccgaagag ttgcggcagc aaacgcaaag cgccacgctg gaagaagcat ttataaatct
     2341 gttaccgcaa gcacaacgcc aggcgcatca ggcggtagtg atcccaccgt atcaacctga
     2401 aaacgcagag attgccatcg aagcgcgcga tctgaccatg cgttttggtt ccttcgttgc
     2461 cgttgatcac gtcaatttcc gcattccacg cggggagatt tttggttttc ttggttcgaa
     2521 tggctgcggt aaatccacca ccatgaaaat gcttaccgga ttgctgcccg ccagcgaagg
     2581 tgaggcgtgg ctgttcgggc agccggttga tccaaaagat atcgataccc gccgtcgtgt
     2641 gggctatatg tcgcaggcgt tttcgctcta taacgaactc accgtgcggc aaaacctgga
     2701 gttacatgct cgtctgtttc atatcccgga agcggaaatt cccgcgcgag tggctgaaat
     2761 gagcgagcgt tttaagctca acgacgtcga agatgtattg ccggagtcat tgccgctcgg
     2821 cattcgccag cggctatcgc tggcggtggc ggtgattcat cgcccggaga tgctaatcct
     2881 cgatgagccg acttctggcg tcgatccggt ggcgagggat atgttctggc agttgatggt
     2941 ggatctctcg cgccaggaca aagtgactat cttcatctcc acccacttta tgaacgaagc
     3001 ggaacgttgt gaccgtatct cactgatgca cgccggaaaa gtgctcgcca gcggtacacc
     3061 gcaggagttg gttgagaaac gcggagccgc cagtctcgaa gaggcattta tcgcttattt
     3121 gcaggaagcg gcagggcaga gcaacgaagc cgaagcgccg cctgtggtac atgacactac
     3181 ccacgcgcca cgtcagggat tcagcctgcg ccgtctgttt agctacagcc gccgcgaagc
     3241 gctggaactg cgacgcgatc cggtacgttc gacgctggcg ctgatgggaa cggtgatcct
     3301 gatgctgata atgggttacg gcatcagtat ggatgtggaa aacctgcgct ttgcggtgct
     3361 tgaccgcgat caaaccgtca gtagccaggc gtggacgctc aatctctccg gttcccgtta
     3421 ctttatcgaa cagccaccgc tcaccagtta tgacgagctt gatcgtcgga tgcgtgcggg
     3481 cgatatcacg gtggcaattg agatccctcc caatttcggg cgcgatatcg cgcgtggtac
     3541 gcccgtggaa ctcggtgtct ggatcgacgg tgcgatgccg agccgcgccg aaacggtaaa
     3601 aggctacgtg caggccatgc accagagctg gctacaggat gtggcgagcc gacagtccac
     3661 acccgccagc caaagcgggc tgatgaatat tgagacgcgc tatcgctata acccggacgt
     3721 aaaaagcctg ccggcgattg ttccggcggt gatcccgctt ctgctgatga tgatcccgtc
     3781 aatgctaagc gcccttagcg tggtgcggga aaaagagcta gggtcgatta tcaaccttta
     3841 cgtgaccccc accacccgta gcgaattttt acttggcaaa cagctgccat acatcgcgct
     3901 ggggatgctg aactttttcc tgctctgcgc cctgtcggtg tttgtgtttg gcgtaccgca
     3961 taaaggcagt ttcctgacgc tcaccctggc ggcgctgctg tatatcatca tcgccaccgg
     4021 aatggggctg ctgatctcca cctttatgaa aagccagatt gccgccattt tcggtacggc
     4081 aattatcacg ttgatcccgg cgacacagtt ttccgggatg atcgatccgg tagcttcgct
     4141 ggaaggtcca ggacgttgga tcggcgaggt ttacccgacc agtcattttc tgactatcgc
     4201 ccgcggaacg ttctcgaaag cgctggatct gactgatttg tggcaacttt ttatcccgtt
     4261 gctgatagcc ataccgctgg tgatgggctt aagcatcctg ctgctgaaaa aacaggaggg
     4321 atgatgcgcc atttacgtaa tatttttaat ctgggtatca aagagttgcg cagtctgctc
     4381 ggtgataaag cgatgctgac gctgattgtc ttctcgttta cggtgtcggt gtattcgtca
     4441 gcgaccgtta cgccaggatc gttgaacctc gcgccgatcg ccattgccga tatggatcaa
     4501 tcgcagttat cgaaccggat cgttaacagc ttctatcgcc cgtggttttt gccaccggag
     4561 atgatcaccg ccgatgagat ggatgccggg ctggacgccg gacgttatac cttcgcgata
     4621 aatattccgc ctaattttca gcgtgatgtc ctcgccggac gccagccgga tattcaggtg
     4681 aacgttgatg ccacgcgcat gagccaggca tttaccggca atgggtatat ccagaatatt
     4741 atcaacggtg aagtgaacag ctttgtcgcg cgctaccgtg ataacagcga accgttggta
     4801 tcgctggaaa cacggatgcg ctttaacccg aaccttgatc ccgcgtggtt tggcggggtg
     4861 atggcgatca tcaacaacat taccatgctg gcgattgtat tgaccggatc ggcgctgatc
     4921 cgcgagcgtg aacacggcac ggtggaacac ttactggtga tgccgataac gccgtttgag
     4981 atcatgatgg caaaggtctg gtcgatgggg ctggtggtgc tggtggtgtc gggattatcg
     5041 ctggtgctga tggtgaaagg cgtgctgggc gtaccgatag aaggctcgat cccgctgttt
     5101 atgctgggcg tggcgctcag tctgtttgcc accacgtcaa tcggcatttt tatggggacg
     5161 atagcgcgtt caatgccgca actggggctg ctggtgattc tggtgctgct gccgctgcaa
     5221 atgctttccg gtggttccac gccgcgcgaa agtatgccgc agatggtgca ggacattatg
     5281 ctgaccatgc cgacgacaca ctttgtcagc ctcgcgcagg ccatcctcta tcgtggtgcc
     5341 ggattcgaaa tcgtctggcc gcagttcctg acgctgatag cgattggcgg cgcgtttttt
     5401 accattgcgc tgctgcgatt caggaagacg attgggacaa tggcgtaaat acagtgcccg
     5461 atacgcaagc ttatcgggcc tacgcgatgg tgcaatttat tgaattctag tggttttgta
     5521 ggccggataa ggcgtcacgc cgcatccggc gaggatttat tttaccgacc gatgcccctc
     5581 attcatcatc aggattttgc tatacacatc ttcctcgacg gcgttttttg ctgatgccat
     5641 cactcgtgcc agattcgcct cgttgtgatt attcacatac gctttgccga ctgcggtgat
     5701 aaacgctttg cgcagatcgc tggcgatatt cactttagcg acgcgataat taacgaaact
     5761 gcgtaatatc tccggggcga taccggagcc gccgtggata accagcggca ccgggctgac
     5821 ttcggcaatg cgcttcagca gggggatatc gatccgcggt atatcgtcca ggccatgaac
     5881 gttaccaata gaaactgcca gcatgtcgca accggtgcgt tcgacaaagg tcttcacctt
     5941 ttccggttcc gttttgcaat cggcctcgct gacgtgatca tcttctttgc cgagaatcgc
     6001 ccccagctcc gcttcaaccg gcacgccata agatttacag aaatcgacag cttcctgggt
     6061 gaaagcgata ttctcttcaa aagagaatgc ggcaccgtca atcatgaccg aggtaaagcc
     6121 cgcgcgcacc gcctgtttaa catcctcctg ggttttcccg tgatccagat gaagactgac
     6181 cggaacatcc attttatcgg cgtgacgttt cacgatttca tatatgtaat cgtatcccga
     6241 cagttgtgca ttggtgggcg caatctgaat gaagttgggt aatcccgaac gctcaatagc
     6301 gtttaaaatt gaaattgtcg tctccagatt ggtggtatta aacgcgcccg ctaatacccg
     6361 tttttcctga atgcggtcga gcagtatccg tccattcact aatggcatat tgaaaacctc
     6421 attttttaat atcagttaat tattcagctt caccgaagcg gtcgcgaaat aaggcggtga
     6481 gagtctgtat ggcctcgttt tcatcatcac cgtcgcagcg tatttccacc gtttttccgc
     6541 cttttattcc ggcgcgcata atattcatca tactggtggc attaatatca ttaccctcat
     6601 agtgcagcgt cactttacag ctacattttt tggcggcttt cgccagacag gccgccggac
     6661 gtgcatgcag gccagtactg tttctgacct ccacggtttt agtcaacata gtgctcctcc
     6721 cgatgatgta atggcatcac gccttcttgc tgtaatttca actgatacca gcttttccat
     6781 ttgtgctgat aacgctgtaa ttgatgatat cttgcccgat tcggtaacaa acgttgggct
     6841 atggtaactt gcggcggcgg aatatccggt gccgcggtta ataaggctcc gacagaaacc
     6901 gcctcgctaa atgcaattgc ttcaaccgga cgctgtaaaa tatctgcctt taattgcagc
     6961 caaagggggt tatgggtcgc cggaccgatc acttttaaca cgctggtgcc aggcacatta
     7021 aaacaggcaa agcagttggc aaattccatg gttaatccca gtgagacgct ggaaattaac
     7081 atgtcgatat ttaacgtatc gccaagccca taaaataatc cgcgggtgtg gcgattttta
     7141 tagggtgaac ccgaaccgcg aagatgcgga ataaagacgg gaatgtcatc aagcgaccag
     7201 ttccccgcca ggtaatccgc atacccacga ttgagcgacg cggcgatctc ctcatcagtt
     7261 agccggaacg tgttgcgcag ccactccagc gcgaaaccgc ccacgggcag agaagcaaac
     7321 agggtgaact ggttggcaag cgagtaacag ccgtttgcca gcttgtcacg tttggcctgt
     7381 tcatccagcg tcggttgtgt atccagttgc agaatgcctt ccgtggtgcc cgtcgagtta
     7441 aggatatcgc ccggcatcat ctgcaacgcc cgcgcaccca ccatatggtc atgtccggcc
     7501 agcgtcacgc tgaccggttg cgagaaccca agcgttttgc agagcgactc gctgacccat
     7561 ccggcgtgtt cgcctggctg caccaatggc gcaaatgctg aacagggaac gtgtaacaac
     7621 gccgtcgctt tcgctgacca ttcgcctttg cgcacgtcca gacacagtgt acggctggct
     7681 aaggtgatat ccgttcgctg ttcgccagtc agccgccaga gcagcacttc cggtgcatgt
     7741 agccagcgca ggccgcgacg attgcgcagc ggataatgct ccagcaacca acgcattttg
     7801 aaggcagagt aattgctgtg cagtggtaat ccgcaaatgt cataaagtgc cgcactgtct
     7861 gcctcgctaa gcgttgccag atactcttca ccgcgacggt cataccatgc cagcattggc
     7921 gtcaggatct cgccatgttc gtcaagaaac acccctgact cgccaaaact ggcaatgctg
     7981 atccgcctga caggcagcgg tgaagcggcg ttcagttgcg ctatcgcctg gcggacctcc
     8041 tgccagaggg cgtcgatatc gaaatcgaca tcgccctgtg gggagatctg ttttgccgtc
     8101 acgaatttat gcgcgcccaa cgtcgttgcg tccaggcagg aaaagcaggt gactttgcaa
     8161 ttggtggtgc caatatcgat aacgatagcg gcgctgttat caggcataaa ccgtgctccg
     8221 cgtcattcgg aaaatgccat acagcaccag ggcaataacc ggcaccagag caatggcgat
     8281 gagattgccg ttgaagattt ccagcagcca gaagcggaac gggttaccgc catcaaggaa
     8341 actggaaacc tggccgctgg agccttcggc aaatttgaag ttaacgtctt tcgccattcc
     8401 ggtaataaac ggcgcgattt tggtagcaat ccacaggtcg gcaataatca ccgggatcgc
     8461 cgccagaacg gtgcggaaaa tgttgccacg gctggctaaa gcaatcatcg acgccattac
     8521 cgccaggttg gcaaggtcgc caagcggcag gacttcatta cctgggagga caaacgcgat
     8581 aaagaccgag attggcgtta gcagcagggc ggtggagata atcgccggat tacctacggc
     8641 aacggcgata tccaggccga tatagagatc gtcacggtca gggtatttgg cattgagata
     8701 ctttttaatg gcttcagaca gcggtaataa accttccatc agaatgcgaa ccatgcgtgg
     8761 caggatgaac atcacaccgc caatgctgat gccaagcagc aatacttttt tgaaatcgta
     8821 tccggcaatt acgccgagaa aaatgcccag aatagtgcca accatcatcg gttcgccgaa
     8881 aatgccaaac tttttctgta cggtttccgg atcgatatga atacgattga ggccggggat
     8941 atggtcgatg attttgtcga ccaacagacc gaccggaaag aacaccaccg aagagagcgt
     9001 cggcaaagag atcccttcca ggccaaagta tttttgtacc agtggcgcag accagtcggc
     9061 gagtttaagt actaccaccg cagcaatcgc cgccgccagc aaaccaaaga acaggctgcc
     9121 ggagctgtaa taaaccagcg taccggcaag ggcaaaatgc cagtagttcc acatatctac
     9181 gtcaacggtg cgggttttat ttaacgccag catcgccacg ttaatcagaa tagtcagggg
     9241 aataacaaac ggggcaattg gcgaacccca tgtaatagcg gaaagcggcg gccagcctaa
     9301 atccaccacc ggtaaattaa ttccggtgcg ttcaaccatc gcctgggccg ctggcccgac
     9361 attgctggta agaatatcga aaatggcata aataccgaca aaaccaatgc cgaccgttaa
     9421 tgacgaacgt aaggctttag cgggttttac tttgaaaaag agagcaagaa taaataacac
     9481 caacggcaac attaccgtgg gaccaaatcc caatatatat tgcacaatat tatagagggt
     9541 atgcgcgata tcgttcataa taaacctctt tttcaggcga gagcgcacct cgcgttagcg
     9601 cctgatgtag tgtgttgaaa ttaattatta ttaattactt ttttaggata gaaacaattt
     9661 gcgccaatac tttctcttcg ccaataccag taataattgg caagccgtta accaccggca
     9721 cgtcgagttc ataaggcact ttagtcgttg aaacaaccag tgctacgccg tcggtatttc
     9781 caggtaaaga ggcaacgttg gtttgagaat aattaacgtt aagaccgtgc tctttacaat
     9841 attccatgac tttttctgtt actgccgtgg atgtggcaat acccgtggcg cagacaaata
     9901 aaatggtttg actcatattt cacctcgttc tttcattttg tttaagattg ctgtgtgtat
     9961 ttctgttgtt tccatcgtaa gcagggcgca cataaagggc gtatcctgaa tcatctccat
    10021 aatccacccc agggcattta attgtttgtt actttcgcct aaggcgagca aaaaaatcac
    10081 cctgacaggt acgggatcag ggtcgccgcc catatcggca aacactaccg gttccggcag
    10141 gatgccgacg gcaattgcat tgtgcctgac atgtttatgg tccgtgtgcg gaatggcgac
    10201 acacggtggt tcggtaggca gtcccgttgg gtacgtcgcc tcacgttcca gtacatgatc
    10261 ggcaaaatca gggaccacca gttcggcggt aaccaacggt tgcgctaact gacggatgat
    10321 ctgttcaacg cttaaccctg ccggaagtcg ttgaataaaa ttttcctgaa actgtatgcc
    10381 ttgcatttta ttcctcttaa aaaagtgtac ttaactcact tcccgccgtt gcagcacggt
    10441 gccaagatag tatttatttc cttttaacca gacgttgcca aactcaacgg gtaatccgcg
    10501 ggagaaaaag actaactgct ccagatgcaa aacgggtgca tcttcactga tatctaaaaa
    10561 atgaccgcgt tcattaccaa ttaatcgcgc ggcatagcga ctttccgagt aacgaatttt
    10621 tctttgcgac aaactttcta ttgttggaaa taaattgtgt tgattaaaat cgatttccac
    10681 gatgccgggg catagctcaa tattgatacg gttctctatc agcatcgctt tttcatcacc
    10741 aattgaacgt aaacgctcaa ggtaaagaat atcctgaccg ggcgttattc ttaatttctc
    10801 tgccacataa cgattagccg gttcaatccg tgacgtaata acttcagtgg taaaatgtat
    10861 tttctggctt tccagcgatt ccgcgaatga caataatcct tcacctaacg gatatgccac
    10921 gttctctttt ttgacaaatg ttcccttccc ctgaacctga atcaacacgc cttcttttac
    10981 cagttgggcg accgcttttt taacggttcc ccgactcact tccagcatat ccataatctg
    11041 gtattccgaa ggaatgcgat cgtcttccac cagatccccg gtataaatac tttctcttat
    11101 ccactccacc acttgttgat agagcggtat ttgtgacgac ttactcaatg atttcatggc
    11161 gcgcacctga acatttacag ttgtctatgg acaatcatgg acaacttcaa gcgtatagta
    11221 ggtgaacagg cgaaaaagag gatcgaagcg tctcacattt taggggacca aatcgtgatc
    11281 aaaaaaatgt gacgtgagtc gatatttggc aggagtctac tgcgccgtca ggaaataacg
    11341 gcgcgttggg aggtgttaat cttccttcgg caggcactgc aaatgcccgt gccgcacgcc
    11401 gcgctgggcg atgacgtcgt cggcaaaatg ttgtacgtca cccatgtcac ctttcaacac
    11461 ggcgatttcc agacagtcgt cgtgattaat gtgcacatgc agagtagcaa ccgagagatc
    11521 gtggtgatga tgctgggtgg agacaatacg gctggctaag tcacgttttt cgtgttcata
    11581 cacatacgac agcaccgcga aaccttgtgt gccgtgttgt tgagtggctt cctgcgccag
    11641 agcgctacgc agaatatcgc ggatcgcctc ggaacggttg ttataaccac gacgctggct
    11701 caggctgtcc agcgtctcca gtaaatcgtc atcaagcgtg atggtgactc gttgcatttg
    11761 cgttaaacct tttctgtggt gcgacggcgc acggggaatg cgggtaatac cgcgttttgt
    11821 agcacacgtc cggcgtcaga ggaaaaggtt aatttatctc ccaccacctg ggtttcgacg
    11881 atttgtccgt tgtccatcac catcacccgc tgacagaagc gttccaccag gcgtaagtcg
    11941 tgggtgatga acaggcaggc ggtgccaaac tgttgttgca gctttttcag caggcgaatg
    12001 acgcccgcct gtaacacgag atcaaggttc gaaacggctt catccagaat cagcagtttc
    12061 ggttcgaccg ccagcgcgcg tgccagacag acacgctgga gctggccgcc gcttaactgc
    12121 ggtgggcgtt tgtcgagcac gctgtcgtcg agatcgaccg ccttcagcat ttcgctggtg
    12181 cgcgccagtt gttcggcttt tttcagcgat agcaggtggc gcatcggttc acgcaggatc
    12241 tcgcgcacgg ttttgcgcgg attcacggcg ctgatggagt cctgaaacac catttgaata
    12301 tcacggcgga acgctttacg ttgcgcgcga ttgagcttcg ccaacggttc gccgcgccag
    12361 ctaatatttc cctgtgaggg cgactctaac cctaccagca gccgcgcgag ggtacttttt
    12421 ccgcagccgc tgcgtcccag cagggcgacg gtttcaccgc ttttcagggc cagggaaacg
    12481 ttattcagca ccgcctggtg ctgatgtttt ccgctaaatc caccgtgcgc atagtgatgg
    12541 gaaaggtcgg agacgttaag taaagtcatg atgccagctc cataccgtag agggcgagat
    12601 gcgcggaaac caggctgcgc gttaccgcat gtttgggggc gttaaacagc gtttctacat
    12661 cgccctgttc gacaatttta ccgtgagaca ttaccgccac atcgtctgcc agacgcgcta
    12721 ctacgcccat atcatgggta accagcagca ttcccggtgc ttgtttttgc ataatgcttt
    12781 ccagtagatc gaggatgcgt gcttgtgcta ccacgtcgag atcggtggtt ggttcatcgg
    12841 cgatgataaa cggtgattcg cacagcaccg ccatcgcaat catcatgcgc tgcaacatgc
    12901 cgccgctcat ctcgaacggg tagagcttca gcacgcgcgc ggcgttttcc agccccaccg
    12961 cttctatggc agcggtaagc gtagcgtcat cggcgggttt ccccagcgcc aggcaggttt
    13021 cacgcgcgtg ggtgtgcatg gtgtgcagcg gattaaaggc actgcgcggg ttctgcatga
    13081 tggtggcaat tttgatgccg cgcagggcgc agggagaaac cggttttcca tcggccaaaa
    13141 tttcccccgc cgtctggcga acgcctgcgg gcagaatgcc cagcgtcgcg gcgcaggtca
    13201 gcgacttccc gctgccacta ccgccgacta acgccagcac acgcccacgt tgcagggtta
    13261 acgatacgcc gtgcaccagc ggctgcgcgg cctgtagcgc gatattacgg agttcaatct
    13321 gttgtggcat tagtgtgcgt gctccgtcac cagatgaggg tccagatgat cgcgcagtgc
    13381 gtcacccacc aggttaaagg ccatcacgct gataaacagc gccagccccg gccagaacat
    13441 ttgcagcggc tgggtccaga tatactgacg cgcgtcgtta atcatcacgc cccattcggc
    13501 ggtcggcgcg gtcacgccga gaccgaggaa ggacatcccc gcgacgtgta gcatcatatg
    13561 accgatatcc agcgtcgcca gcaccagcag cgaggggatc accgcacctg ccagatgatc
    13621 aataaacacc cgcacatggc ccgcgccaga aagccgtgat gccagcacaa actcgcgctg
    13681 gcgcagtgaa atcaccagac tgcgcaccat gcgcgcgtac catgcccagt gcgaaagggc
    13741 gatagcgata attacgttgg tcaacccggt gccaagcacg ccgaccataa agaacgacag
    13801 aatcgaggtt gggaaggtca taaacatatc cgcgacgcgc atggtggcct gatcaacgcg
    13861 cccgccaatc agcccggcgc tgccgccaat aatcagccct aatgtcagca ccaacagcag
    13921 gcaggccatt accgagccga gcgacacgcg ggtcgctgcc atcagccgcg agaaaatatc
    13981 gcgccctaaa tgatcggtgc ccagccagtg ctgcgcatcc ggcgagagca ggcgcgacgg
    14041 caaatcaata gcctgagggt catacggcag ccaccactgg ctggtgagcg caatcagcgc
    14101 cagcagggcg ataatgatca gcgccaggcg aaccgaccag cgggaggaga ggaaaaagtt
    14161 cacgcgtgcg ctccttcatg acgacgaata cgcgggtcca gcgcggcgtt gagcaaatcg
    14221 acaatcaaat tacagaccac aaaaaccacc accatcatca gcgtaaagca ctggatcacc
    14281 ggatagtcac ggttaaaaat cgccgacacc gcatagcgcc cgacgcccgg ccaggcaaag
    14341 atgttttcga taatcatcgt cccgccaatc agttcgccaa tgtgcatccc cacggcagtg
    14401 atcatcggca gcgaggcatt gcgcagaata tggcggcgtt cggtctgttt gtcattcagg
    14461 ccgcgcagcc gcgcccaggt cacatgacgc tgaccggcga cgtccagcat actggcgcgc
    14521 agcaaacgcg cgttaatcgc cagcgacata aaggcgatgg ataccgcagg caaaatgatg
    14581 tgctgccagc cgccgtaacc catcgcgggt agccattgca gatacaccga aaacgccatc
    14641 accagtaaaa acgccagcca gaagttaggc atcgacacgc cgagaaacgc gatgaaacgg
    14701 acggcgaaat cgggcaagcg atcgcggtgg cgcgccgccc agataccgag cggcacggag
    14761 gtgagcagaa ttaataccag cgccgcaccc gccagttcca gcgtggcggg caggaagttc
    14821 agcatatcgt ccagcaccgg gcgttggctg gcgaatgaga taccaaagtc aagatgcagc
    14881 gccttccata gccaggtgcc atactggacg tacagcggct gatccagccc cagcatagtg
    14941 cgggtagagg ccagcatctc cggcgtcggc ggcaggttag ataaacgcaa ataatcaagc
    15001 gccgggtcgc cggtgccgag gcgcagcatc aaaaaaatga tcaccgaggc ggcgagcacc
    15061 atcgggatca gcagcagaaa gcggcgtaat acataacgca acattaaggt ttcaccggtt
    15121 taatctgttc gaacgggatt tcggtggcga tcggcgcgta ggggatgtta cccagttccg
    15181 gttttgaaac caccatcatt gagatgtaac tgataggcag ataaaccgcc tcgtcatgca
    15241 gacgggtcag aatgtcgcga tacagcgcct gacgttgcgt ttcgtcatgg gtcgccagca
    15301 cttcgccgat ctctttatca atcagcgact tgtcggctaa accttgctgt gcctggaagt
    15361 cagcgtgcga cggtacgcgc attgaactca ggaaggcgtg tggatcgtat ggcgcgcccc
    15421 aggtgcggtg gaaaatcatg ccaaaacgac cgtcgcgctg acgagcatag atactgctct
    15481 cttcttcgcc aatcagcgag acatctgcgc caatctggcg catatcagcc tgaatgattt
    15541 ccgccatcga tttgcttaac gcatcggtgc cgatgaacga cagttcaatg cgcagcggct
    15601 gaccattttt ctcgcggatg tctttgccag caggcagcgt ccaaccggct ttttccagca
    15661 acgctttcgc tttctgcgga tcgtactggc gcggtttcag gccgaggttg gcgtagggca
    15721 cagaaggggc aaacagggtg tcggcgacct gctgggtacc atacaacgcg ttatcaatca
    15781 gcgatttttt gttcaccgcg taattaagag cttcacgtac tgccagctcg ttggtggggg
    15841 ctttggcggt attgagcgcc agcatcacgg tttcgatcgg ctgtgacagt tgagtgtggt
    15901 aagccgggtt ctggctaaag cgggcgaagg tatcgagcgg taataaccct tcgtttccgt
    15961 acagcaggtc gatatcgcca gtttcaaacg ccaccgcgcg ggtagtcggg tccgggatca
    16021 cgttaaaggt gatcttttta atcgccggtt tttcgcccca gtagttttcg ttacggacga
    16081 agacatcgta ctgattcagt ttcgattcct gcaaaaccca cggtccggtg ccaatcggcg
    16141 cttttatccc gttcatggtt tcgtgatttt taaattgtga cggggcaata aagcggaaag
    16201 gacgcggcag ggccagttct tgcaggaaag gatagtaggc gcttttcagg gtgatttgca
    16261 gctcgttttt gctgagtgct ttgacatcaa caatctggtt tgccagctcc agccaggcgt
    16321 gacgttgacg gttatcgagc actgcacgga agttttctgc cgccgcctct gcatcaaacg
    16381 gttcgccgtt ggagaatttc acgtcatcac gcaaggtgaa ggtccaggtt ttgccatctt
    16441 ccgaatgggt ccagcttttt gccagccacg ggatcaccga accgtctgcc tgatatttca
    16501 ccagcggttc ataaaccatg ctctgggcga acatttggtt aggcgtgtaa aggtgcgggt
    16561 ttagtggccc gacattcacc ggccaggcgg tggtgatttc atctggtgca gcggcatgga
    16621 cgataaaaga cgcacaagcc agcagcgcaa atagagtgcg gcggagtgta gagaacatgg
    16681 taaccccaat ggattaaaat agatggcgga aataagtatg acgattttaa gtattcgtca
    16741 tactgattac ctgttctgga tcaatagatg ggcagtcggg tgggcggatc agttaactga
    16801 atcgatccat tgcacactgt cggcggtgag cgtaaagggg gtaggggtgc agatcgccag
    16861 gcttaaattt tctagctgac aatggctgac tgacagcgag gagttatagg tgctgtctac
    16921 gctgacgatt tgccaggcgc tgccgccacg ctgtttaacg atggcttctt tgcgcgtcca
    16981 gatgcgccag aacatttcca gttgctgatc aggatgcacg gcgtccatct cggcatgttc
    17041 cccgaggctg aatacggcgt tcgccagcca gcgccagttg gcgcgcgggc gaatcacttc
    17101 gatatcgcag ccgacttcgc cttcatcgct caacagcagg gcgatatcgt caccgctatg
    17161 gcttaagttg aaccatagcg gcgtttccgg cgcgaatgca ggtttgcctt gttcgccata
    17221 gatgatctcc ggtagcgggg aaagcgtgtg cgaaagcaat gcacgccccg ccagccagcg
    17281 ttcgcgtcgt ggaccttgcg gtgcttgctc gcgtaaaccc agtggcagag gagctgcgct
    17341 taaggtcgaa actttcccca gaactatccg atacatatca gggccaacgt ttaatggaaa
    17401 atgaaagtgc gtatcgtaac acttgtcgcc tcatcccggt aaccgacttt tcggtctgcc
    17461 tggccccagt aaaatcgcca gtttgctgcc gcctttggtg gtttccatcc agattttaca
    17521 cacgctggtt aatggcaccg aaagtagcat ccctaccggg ccgagcagcc atccccaaat
    17581 taacaatgaa agaaatacca ccatggtgga catccccagg cgatggccca tcatccgtgg
    17641 ttctaaaata ttgccgatga ccatatggac cactaaaaac aatgcgccga ccagaataca
    17701 ttcgtaaata ccattaaaca gcagcacctg aatcattggc ggtacggcgg aaattaccgc
    17761 accgatattg ggcacgtagt tgagcaaaaa cgccagtact gcccacatca gcgcaaactg
    17821 cacccccatc agctccaacc ccagccagac gattacgcct gtccataaac tgagtagcgt
    17881 ctttaacgcc agataatgcg aaacgccttt aagtgcgcgg tgtagtccgg cgatgtgaat
    17941 ctgtggatta ttcaacgcga aacgcatttt gtaagggacg tggcgcactt caaacagcat
    18001 aaaaactacg gtcatcacca gcaaaagcac gctcgccatt gccccggaaa gcccggtcat
    18061 tagcgccgtg gtgaaggtaa ccactttttc cgagtccatc cgctgtagta ttcgctccgg
    18121 cgacatatgc aaattaagaa aaggcaacat ctcctgcaat ttaaaaagtt tgcgcgtcag
    18181 ctccttatta aacttcggca gcatagagat aaattcgtta aacgatgccg ccagtacgcc
    18241 gaccagcgcg gtgagtgcga tcagcatcac cacaaccaca atcgtaatgg caacggggcg
    18301 ttgtactccc cgacgaataa accaggtgac gagcgggttg agaacgatgg caaaaaacag
    18361 cgccagtaat agctgcacaa tgatatctgc cgctgcgtga atgcccgcga ggatcactac
    18421 cagcgaggcc aacttgagca gaatgcgcat gcccgtttta tcgggttgag gggtttccat
    18481 tggggcttcc ttgtgacttt ttgtattaag tgtagcggga gtcacgccag caatattctg
    18541 attcttactg ctgattttca cgtcagcaca tggtaaaaat gaaacactgt tgtaaaaatg
    18601 tggtgatcct catgcccgaa cccgtagccg aacccgcgct aaacggattg cgcctgaatt
    18661 tgcgcattgt ctccattgtc atgtttaact tcgccagcta cctcaccatc gggttgccgc
    18721 tcgctgtatt accaggctat gtccatgatg tgatgggctt tagtgccttc tgggcagggt
    18781 tggttatcag cctgcaatat ttcgccacct tgctgagccg tcctcatgcc ggacgttacg
    18841 ccgatttgct gggacccaaa aagattgtcg tcttcggttt atgcggctgc tttatgagcg
    18901 gtctgggata tctgacggca ggattaaccg ccagtctgcc cgtcatcagc ctgttattac
    18961 tgtgcctggg gcgcgtaatc cttgggattg gacaaagttt tgccggaacg ggatcgaccc
    19021 tgtggggtgt tggcgtggtt ggttcgctac atatcgggcg ggtgatttcg tggaacggta
    19081 ttgtcactta cggggcgatg gcgatgggtg cgccgttagg tgtcgtgttt tatcactggg
    19141 gcggattgca ggcgttagcg ttaatcatta tgggcgtggc actggtggcc attttgttgg
    19201 cgatcccgcg tccgacggta aaagccagta aaggcaaacc gctgccgttt cgtgcggtgc
    19261 ttgggcgcgt ctggctgtac ggtatggcgc tggcactggc ttccgccgga tttggcgtta
    19321 tcgccacctt tatcacgttg ttttatgacg ctaaaggttg ggacggtgcg gctttcgcgc
    19381 tgacgctgtt tagctgtgcg tttgtcggta cgcgtttgtt attccctaac ggcattaacc
    19441 gtatcggcgg cttaaacgtg gcgatgattt gctttagcgt tgagataatc ggcctgctac
    19501 tggttggcgt ggcgactatg ccgtggatgg cgaaaatcgg cgtcttactg gcgggggcgg
    19561 ggttttcgct ggtgttccct gcattgggcg tagtggcggt aaaa
//
LOCUS       DAFGPF010000089        19403 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFGPF010000089 DAFGPF010000000
VERSION     DAFGPF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19403
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.089"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            18..2408
                     /gene="gcd"
                     /locus_tag="LSX49_003601"
     CDS             18..2408
                     /gene="gcd"
                     /locus_tag="LSX49_003601"
                     /EC_number="1.1.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="HBL7169962.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLSVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEISGTLSADTTPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHKLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPIIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     gene            complement(2455..4005)
                     /gene="cueO"
                     /locus_tag="LSX49_003602"
     CDS             complement(2455..4005)
                     /gene="cueO"
                     /locus_tag="LSX49_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HBL7169963.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFNADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVNELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRNLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHSGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPATHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            4171..4518
                     /locus_tag="LSX49_003603"
     CDS             4171..4518
                     /locus_tag="LSX49_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HBL7169964.1"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            4624..5490
                     /gene="speE"
                     /locus_tag="LSX49_003604"
     CDS             4624..5490
                     /gene="speE"
                     /locus_tag="LSX49_003604"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBL7169965.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALP
                     QYLQDALASQPS"
     gene            5506..6300
                     /gene="speD"
                     /locus_tag="LSX49_003605"
     CDS             5506..6300
                     /gene="speD"
                     /locus_tag="LSX49_003605"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBL7169966.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTTEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(6338..6700)
                     /locus_tag="LSX49_003606"
     CDS             complement(6338..6700)
                     /locus_tag="LSX49_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HBL7169967.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(6875..9472)
                     /gene="acnB"
                     /locus_tag="LSX49_003607"
     CDS             complement(6875..9472)
                     /gene="acnB"
                     /locus_tag="LSX49_003607"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019080489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HBL7169968.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFDQLSQYTEKA
                     DGVIFQTAV"
     gene            9827..11590
                     /locus_tag="LSX49_003608"
     CDS             9827..11590
                     /locus_tag="LSX49_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HBL7169969.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASAGLYIKSRTVEAPVEAQSTQ
                     QTAPDISAVTLPATVSVPPVTPAVVKSAFSTAQIDQWVAPVALYPDSLLSQVLMASTY
                     PANVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKIITTTKKVVPVNQPANAPATQSN
                     TVSTSSPVVAEPAPTVITIEPANPDVVYIPNYNPNVVYGSWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHDHHHHDDDDYHHHDGGHRDGNDWQ
                     HNGDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVTYHDQDMAKRFHQTDVNGGM
                     SATQLPALSRDSQRQAAASQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGNYDDFRE
                     FSRHQPLTQQQKDAARQRYQSASPEQRQAAREKMQTSPQNQQQRDAARQRIQSASPEQ
                     RQVFKEKVQQRPLNQEQRDNARQRVQSASPEQRPFFREKVQESRPQRLNDSNRTARLN
                     NEQRSAVRERLSERGARRLER"
     gene            complement(11661..13085)
                     /gene="lpdA"
                     /locus_tag="LSX49_003609"
     CDS             complement(11661..13085)
                     /gene="lpdA"
                     /locus_tag="LSX49_003609"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL7169970.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(13293..15185)
                     /gene="aceF"
                     /locus_tag="LSX49_003610"
     CDS             complement(13293..15185)
                     /gene="aceF"
                     /locus_tag="LSX49_003610"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBL7169971.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAASAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            complement(15200..17863)
                     /gene="aceE"
                     /locus_tag="LSX49_003611"
     CDS             complement(15200..17863)
                     /gene="aceE"
                     /locus_tag="LSX49_003611"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HBL7169972.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            complement(18024..18788)
                     /gene="pdhR"
                     /locus_tag="LSX49_003612"
     CDS             complement(18024..18788)
                     /gene="pdhR"
                     /locus_tag="LSX49_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HBL7169973.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     gene            complement(19244..>19403)
                     /locus_tag="LSX49_003613"
     CDS             complement(19244..>19403)
                     /locus_tag="LSX49_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL7169974.1"
                     /translation="LEEHLTRITQHPLMSDLIYYPAKKGDDEPENILKIVKEWRRSQG
                     LPLFKDSE"
BASE COUNT         4492 a         5322 c         4846 g         4743 t
ORIGIN      
        1 tgaaatggtg tctctttatg gcaattaaca ataccggctc gcggcgatta ctcgtcacgc
       61 taacagccct ttttgcagcg ctttgcgggc tgtatctact cattggcgga ggctggctgg
      121 tcgcgattgg cggctcttgg tactacccta tcgctggcct tgtgatgctc agcgtcgcct
      181 ggatgctgtg gcgcagtaaa cgcgccgcgc tttggctgta cgcagccctg ctgctcggca
      241 ctatgatttg gggcgtctgg gaagttggtt tcgacttctg ggcgctgact ccgcgcagcg
      301 acattctggt cttcttcggc atctggctga tcctgccgtt tgtctggcgt cgcctggtca
      361 ttcctgccag cggcgcagtt gccgcactgg tggtcgcact gctgattagc ggtggtatcc
      421 tgacctgggc cggatttaac gatccgcagg aaatcagcgg caccttaagc gccgatacca
      481 cgccagcaga agccatctcc cccgttgccg atcaggactg gcctgcctat ggtcgcaatc
      541 aggaaggtca acgcttttca cctctgaaac aaattaacgc tgataacgtc cacaagctga
      601 aagaagcctg ggtgttccgt actggcgatg tgaagcagcc gaacgatccg ggcgaaatca
      661 ccaatgaagt gacgccaatt aaagtgggcg acacccttta cctgtgtacc gcgcaccaac
      721 gtctgtttgc gctggatgcc gccagcggta aagagaaatg gcattacgat cctgagctga
      781 aaaccaacga gtccttccag catgtaacct gccgtggcgt ctcttatcat gaagccaaag
      841 cagaaactgc ttcgccggaa gtgatggcgg attgcccgcg tcgtatcatt cttccggtca
      901 atgatggtcg tctgattgca attaacgctg aaaacggcaa gctgtgcgaa accttcgcca
      961 ataaaggcgt gctcaatctg caaagcaata tgccggacac caaaccgggt ctgtatgagc
     1021 cgacttcgcc gccgattatc accgataaaa ccatcgtgat ggccggttca gtcaccgata
     1081 acttctcaac ccgtgaaaca tctggcgtga tccgtggttt tgatgtcaac accggggagc
     1141 tgctgtgggc ttttgatccg ggcgcgaaag atccgaatgc gatcccgtct gacgaacata
     1201 cctttacctt taactcacca aactcgtggg caccagcggc ctatgacgcg aagctggatc
     1261 tggtctatct gccgatgggc gtcaccacgc cagatatttg gggtggtaac cgcacaccgg
     1321 aacaggaacg ttatgccagc tcgattctgg cgctgaatgc cactaccggg aaactggcgt
     1381 ggagctacca gaccgttcac cacgacctgt gggatatgga tcttccggca cagccgacgc
     1441 tggcggacat caccgttaat ggtcagaaag tgccgattat ttacgctccg gcgaaaaccg
     1501 gcaacatttt tgtgctcgat cgtcgtaatg gtgaactggt ggttccggcc ccggaaaaac
     1561 cggttcccca aggtgctgcc aaaggcgatt acgtgacccc tactcaaccc ttctcggaac
     1621 tgagcttccg tccgacgaaa gatttgagcg gtgcggatat gtggggtgcc accatgtttg
     1681 accagttggt gtgccgcgtg atgttccacc agatgcgcta tgaaggcatt tttacgccgc
     1741 catctgaaca gggtacgctg gtcttcccgg gtaacctggg gatgttcgaa tggggcggga
     1801 tttccgttga tccgaatcgt gaagtggcga ttgccaaccc aatggcactg ccgtttgttt
     1861 cgaaactgat cccacgcggt ccaggcaacc cgatggaaca gccgaaagat gccaaaggca
     1921 cgggtacgga atccggcatc cagccacagt acggtgtacc gtatggtgtc acgctcaacc
     1981 cgttcctctc accgtttggt ctgccatgta aacagccagc atggggctat atctcagcat
     2041 tggatctgaa aaccaatgaa gtggtgtgga aaaaacgtat tggtacgccg caggacagta
     2101 tgccattccc gatgcctgta ccggtgccgt tcaatatggg tatgccgatg cttggcgggc
     2161 caatctccac ggcgggtaac gtgctgttta tcgccgctac ggcagataac tacctgcgcg
     2221 cttacaacat gagcaacggt gaaaaactgt ggcagggtcg tttaccagcg ggtggtcagg
     2281 ctacgccaat gacctatgaa gtgaatggca agcagtatgt ggtgatctcc gcaggcggtc
     2341 acggttcatt tggtacgaag atgggcgact atattgtggc ttatgcgctg ccggatgatg
     2401 tgaagtaacc ataatgcccg gagagatccg ggcatatttc cgaatacggt ctttttatac
     2461 cgtaaaccct aacatcatcc ccgtatcttc atgctccagc agatggcagt gcgccatata
     2521 agcatgttct ttcggtgcat cgtgattaaa cttcaccagc acttcgctga cattaccttc
     2581 taccttaacg gtatctttcc agcctgcgcg atgcgtcgct ggcggtttgc cattttctga
     2641 caagatacgg aactgcgtac cgtggatatg gaacggatgc agcatcatgt cgcccacgcc
     2701 agagataacc caacgttcgt actgcccttt cgccgccgca aacatcggct tattcatatc
     2761 aaacgcctga ccgttgattt tgttggcatg gtggaaatcg aacttcccgc tgtggttcat
     2821 atgattcata ttgccgtgcc ccatatggcc catcatctgg ctgtgatcca tcccggccat
     2881 ggcctgatcg ccatatttct ccatcagcat ctgcatcccc atcatatcga gcattgggtc
     2941 catagaaagt tgcagattgc gtaccgtcag cccttccagc gaaggtaacg caggcaggct
     3001 acttaatgtg tctggcaaag caccagaggc actaatggca atcggctgaa tccgcattac
     3061 cggatgcggc ttgtcaaacg gcgcaatcgc catccccatc tggctgaccg gcagcgtcac
     3121 caggtcaaag ggtttgttat cgttaacctc caccagcact tcaaaacgct cgcccatcag
     3181 cactggcagc tcgttcacct tcaccggttc aggtagcaga ccgccgtcgc tggcaatcac
     3241 ataaagcggg cgattgtcgc tggtggcgaa attgagcgag cgggcattac agccattgag
     3301 caaacgcagg cgcagccagc cacgcggggc agcgtgttgc gggtagattg caccgttggt
     3361 cagcaacgta tcgccaaacc aacccacagc ggcggtcatc acatccagtt gataatcaat
     3421 ctgcccgtct gcgttaaatt ttttatcctg aacaatcacc gggacatcat caatacccca
     3481 ctgttttggc agcattaatt tcaggatctc gtcatcttca atcaccacca aaccagccag
     3541 ccccatcgcc acctgacgtc cggtcttgcc atgttgatgt ggatggaacc agcaggtagc
     3601 ggcaggttga tcaacgttca acgtcaccga gcgcttgcca cctggcggaa taattccctg
     3661 cgggccgccg tccacttcac ccggtacttc cagcccgtgc cagtgcaacg tcgtctcttc
     3721 cgtcagttgg ttgtagatat caaccgttac cgctttgccg cgctgtaatt tcaccgccgg
     3781 ccccagcaga ttgccgttat agccccaggt agttgcggtt ttcccgccaa aggtggactg
     3841 acctgcgcca atagttaact gaatgcgatt acgggcatcg gtcgtgagca aatcagggat
     3901 tggtaacgtt gggcgttccg ccgcaaatac tgcgcggctc cacagcggca aggctgaagc
     3961 cacccccagc gcgacggaat atttcaagaa atcacgacgt tgcatagtta tttccttatt
     4021 cttaagcagg cgaaacaaaa tcaaacgttg agcatagtcc ttccccttac gggaaggtca
     4081 agccgcagac acaatttaat cgacaataat ggtcgtcgcc tcgctcgcag tgtgctaacg
     4141 tttatcttct ttaagcccct ggtagaagca atgaagacgt ttttcagaac agtgttattc
     4201 ggcagcctga tggccgtttg cgcaaacagt tacgcgctca gcgagtctga agccgaagat
     4261 atggccgatt taacggcagt ttttgttttt ctgaagaacg attgtggtta ccagaactta
     4321 cctaacgggc aaattcgtcg cgcgctggtc tttttcgccc agcaaaacca gtgggatctc
     4381 agtaattacg acaccttcga catgaaagcc ctcggtgaag acagctaccg cgatctcagt
     4441 ggcattggca ttcccgtcgc taaaaagtgc aaagccctgg cccgcgattc cttaagcctg
     4501 cttgcctacg tcaaataatc cctgatacct ttttgtagaa atattgaccg tgcatccgcg
     4561 gtcaatgtta gctattatgt tgcgccattt ttttacgggt gttaacaaag gaggtatcaa
     4621 cccatggccg aaaaaaaaca gtggcatgaa acgctacacg accagtttgg gcagtacttt
     4681 gcggtagata acgttctgta tcatgaaaag accgatcacc aggatctgat catttttgag
     4741 aacgccgcat ttggtcgcgt aatggcgctg gatggcgtag tacaaaccac cgagcgcgac
     4801 gagtttatct atcatgagat gatgacccat gttccgctac tggcccacgg tcacgcgaaa
     4861 catgtgctga ttatcggcgg cggcgacggt gccatgctgc gtgaagtaac ccgacataaa
     4921 aacgttgagt caatcacgat ggtggaaatc gatgcgggtg tcgtgtcgtt ctgccgtcag
     4981 tatcttccca accataacgc cggtagttac gacgatccgc gctttaagct ggtgatcgac
     5041 gatggcgtca atttcgttaa tcaaaccagc cagacctttg atgtcattat ctccgactgc
     5101 accgatccta tcggtcccgg cgaaagtctg ttcacttcgg cattttatga aggctgcaaa
     5161 cgttgcctga atcctggcgg tattttcgtt gcgcagaacg gcgtctgctt tttacagcag
     5221 gaagaggcca tcgacagtca tcgcaaactc agccattact tcagcgatgt tggcttttat
     5281 caggcggcga tcccgaccta ttacggcggc atcatgacct ttgcatgggc gacagataac
     5341 gacgccttac gccatctttc aaccgaaatt attcaggcgc gttttctcgc ttctggcctg
     5401 aaatgccgtt attacaatcc ggcagtccat acggcagctt ttgccttacc ccagtatctg
     5461 caagatgcac tggcttcaca gccgtcctaa ggagaagata agaaattgaa aaaactgaaa
     5521 ctgcatggct ttaataatct gaccaaaagt ctgagttttt gtatttacga tatctgctac
     5581 gccaaaacta ccgaagagcg cgacggttat attgcttata tcgatgaact ctataatgcc
     5641 aaccgtctga ccgaaatcct gtcagaaacc tgttccatta tcggggccaa tattcttaac
     5701 atcgcccgcc aggattacga accacaaggt gccagcgtca ctattctggt gagtgaagaa
     5761 ccggtcgacc cgaaacttat cgacaaaaca gaacaccccg gcccactgcc agaaacggtc
     5821 gttgcccatc tcgataaaag tcatatttgc gtacatacct acccggaaag tcatcctgaa
     5881 ggcggtttat gtaccttccg cgccgatatt gaagtctcta cctgcggcgt gatttctccg
     5941 ctgaaggcgc tgaattacct gatccaccag cttgagtccg atattgtgac tattgattat
     6001 cgcgtgcgcg gttttactcg cgacattaac ggtatgaagc actttatcga ccatgagatt
     6061 aattcgattc agaactttat gtctgacgat atgaaggcgc tgtatgacat ggtggatgtg
     6121 aacgtctatc aggagaatat cttccatacc aagatgttgc ttaaagagtt cgaccttaag
     6181 cactacatgt tccacaccaa accggaagat ttaaccgaca gcgagcgcca ggaaattacc
     6241 gctgcgctgt ggaaagaaat gcgcgagatt tattacgggc gcaatatgcc cgctgtttaa
     6301 cgtctcaggc ggagcacgga ggctccgcct gatttactta cttctgctgc acgaaattac
     6361 ggtaagccgc caccacctga agaaaatcct caacgccaca cagtgacaag ctctcttcat
     6421 cgtagtagtt catcccctct tccatttcat cgccagcgaa ttccagttga ttggcgcgaa
     6481 ccatcacctc ttcaccatcc atccatagcg tgtattcatg ccctgcccgt tgccaggaac
     6541 gttcgctacc tttcaatgcg tgcgccgctt gttccacttc atcaagcaag gccaggtttt
     6601 ctttcacctc ttcattaaac cagtgcccga ccacttcatg ccccatggac atgcgcacct
     6661 ttaccactcc ggtaatatcg cgcagaaatt cgtaatccat agtgtgttcc tctgctcccg
     6721 gcaatgcgcc gaaatcgcat tgcgccattg atgtaattat cgcagtctta ccggagaaaa
     6781 acagcggaac ggcgatggtt tagaaataaa aaatgcccgg gaatctcatt caccgggcat
     6841 tgtgtcgttt atgcgcagcg cgtgcgctta cttattaaac cgcagtctgg aaaatcaccc
     6901 cgtccgcttt ttcggtgtac tgagaaagct ggtcgaagtt cagataacgg taagtatcaa
     6961 cggcagtttt atctacttgc gccacgtagg tctggtactc ttccggcgtc ggcagtttgc
     7021 caatcagcgc cgcaacagca gccagttccg cagaagccag gaagacattc gcgccagtac
     7081 ccaaacggtt cgggaagtta cgggtagagg tggaaaccac cgtcgcaccg tctgctacac
     7141 gcgcctggtt acccatacac agggaacagc cagggatctc gatacgagca ccactcttac
     7201 cgaagacgct gtagtagcct tcttcggtca gctgcgcagc gtccatacgc gttggcggtg
     7261 ccacccacag gcgggtcggc aactgacctt tgtgcgcatc cagcagttta ccagcagcac
     7321 ggaagtgacc gatgttagtc atgcaagaac cgataaatac ttcgtcgatc ttctcgccct
     7381 gtaccgcaga cagcggacgt gcgtcgtccg ggtcattcgg tgcacagagg attggctctt
     7441 tgatatccgc cagatcgatg tcgatcactg ccgcgtattc cgcatctgca tcggcttcca
     7501 gcagctcagg attcgccagc catttttcca tgccctgaat acgacgctcc agggtacgac
     7561 gatcgccgta accttccgcg atcatccact tcagcaggac gatgttagag ttcaggtatt
     7621 caatgatcgg ttctttgttc agcttgatgg tacaaccggc agcagaacgc tcggcagacg
     7681 catcggtcag ctcaaatgcc tgctcaactt tcagatccgg cagaccttca atttccagaa
     7741 tacggccaga gaagatgttt ttcttacctt tcttctcaac ggtcagcaga ccttgtttga
     7801 ttgcatacag cggaatggcg tgtaccagat cgcgcagggt gatacccggc tgcattttgc
     7861 ctttgaagcg taccagaacg gattccggca tatccagcgg cattacgcct gttgcggctg
     7921 caaatgccac cagaccagaa cccgccggga aagagatacc gatcgggaaa cgggtatggg
     7981 agtcaccacc ggtaccgacg gtatccggca gcagcatacg gttcagccag gagtgaatga
     8041 cgccgtcccc cggacgcagc gacacaccgc cacggttcat aatgaagtcc ggcagcgtgt
     8101 ggtgcgtgtt cacgtcaact ggcttcggat acgccgcggt gtggcagaaa gactgcatca
     8161 ccaggtcagc cgagaagccc aggcacgcca ggtctttcag ttcatcacgg gtcatcgggc
     8221 cggtggtgtc ctgggaacct acagaagtca ttttcggttc acagtacgca cccggacgaa
     8281 tgcctttcac gccacaggca cggcctacca ttttctgcgc cagcgagaag ccgcgatcgc
     8341 tctcagcgac atctttcgcc tgacggaaca catcactatg cggcaggcca agtgcttcac
     8401 gcgctttggt ggtcaggcca cgcccgataa tcagcggaat acggccgcca gcacgcactt
     8461 catcaatcag cacgtcggtt ttcagttcga aggttgccag cagttcgccg gtttcgtggt
     8521 tacgcacttc acctttgtac gggtaaacgt caattacgtc gcccatgttc aggttagaga
     8581 cgtcgacttc gattggcagt gcacccgcgt cttccatcgt gttaaagaag attggtgcaa
     8641 ttttaccgcc gaggcacaaa ccaccgccgc gtttgttcgg cacatgtgga atatcatcgc
     8701 ccataaacca cagaacggag ttcgtggcgg atttacgcga tgaccccgta cccacaacgt
     8761 caccgacgta cgccagcggg aaacctttct gttgcagagc ttcaatctgt ttgatcgggc
     8821 caacaacacc aggctgatct ggctcaatac cttcacgggc gtttttcagc atcgccagcg
     8881 cgtgcagtgg gatatccggg cgtgaccacg catccggtgc cggagaaagg tcatcggtgt
     8941 tggtttcgcc ggtcactttg aagacggtaa cggtcagttt ttcagccagc gccgggcgat
     9001 tcaggaacca ttcggcatcc gcccaggact gcattacctg cttcgcatat tcgttacctg
     9061 ctttggcttt ctcttctacg tcatagaagt tatcgaacat cagcagtgtg tgagaaagtg
     9121 ctttggcagc gatcggtgcc agtttggcat catccagcgc gtcgatcagc ggatgaatgt
     9181 tgtaaccacc ctgcatagtg cccagcagtt caatggcttt ttccggagtc agcagtgggg
     9241 atttggcttc acctttggcg acagcagcca ggaagcctgc tttgacatag gcggcttcat
     9301 cgacgccagg gggaacacgg ttggttaaca gatctaacag gaattcttct tcgcccgcgg
     9361 gcgggttttt cagcagctct acaagcgcgg ccatttggtt tgcatccagg ggtttgggcg
     9421 caatcccctc agcggcacgc tcagctacgt gcttacggta ttcttctagc acgacggttc
     9481 tcctcgctct cattgtcata gtgcggcagg cgattctctt cacgctcctg tgagacagca
     9541 gtttgtaggg taaatgccca gtaccgcaac gggcagaata gcaggatttt gacgatgtgt
     9601 taatctgttt acaaaaaagc aacataaaaa agtggctgaa tcgttaagga tggtctagag
     9661 attatttccc tccgtaaaaa cttcgttaat tcgcatggtg ataatcacct ttctcaacga
     9721 atcccaagat tagtcaaaat ttaaactacg gcctctttat actcggattc acagcacctg
     9781 cgggtggcag ttcgccgacc attgcgattt ccttgagatc cgaattatga aaatgacttt
     9841 gccgtttaaa ccccatgtgc tggcgctaat ttgcagtgcc gggctctgtg ccgcctctgc
     9901 cgggctatat ataaaaagcc gcacagtgga agcgcctgtg gaagcgcaat cgacacaaca
     9961 gactgcgcct gacatctccg cagttacgct tccagcaacg gtttccgtgc ctcctgtaac
    10021 acctgccgtc gtcaaatccg cattcagcac tgctcaaata gatcaatggg ttgcacctgt
    10081 cgcgctatac cccgactctc tgctttcaca agtgttaatg gcatcaacct atccggcaaa
    10141 cgttgctcaa gcagtgcaat ggtcgcacga taatccactt aaacaaggcg atgctgctat
    10201 tcaggcggta tctgaccagc cctgggacgc cagcgtcaaa tcactggtgg cctttccaca
    10261 gttgatggca ttgatgggcg aaaacccgca atgggtgcaa aacctgggcg atgcttttct
    10321 ggcgcagccg caggacgtga tggactcggt acagcgattg cggcaactgg cgcaacaaac
    10381 cggctcgctg aagtcatcaa ctgaacaaaa gatcatcacg acaacgaaaa aagtcgtacc
    10441 ggtaaatcag cccgccaacg cccctgccac acaatcaaat accgtttcta cgtccagccc
    10501 cgtcgtcgca gaacctgcac cgaccgtaat aaccattgag ccagccaatc cggatgtggt
    10561 ttatattccg aactacaacc caaacgtggt ttacggcagt tgggccaata ccgcttatcc
    10621 accagtttat ctgccgccgc cagccggaga accgtttgtt gacagctttg tgcgcggatt
    10681 cggctatagc atgggcgttg ctaccacata cgcactattc agcagcatcg actgggacga
    10741 cgacgatcat gaccatgacc atcatcatca tgacgatgat gattatcatc accacgatgg
    10801 cggtcatcgt gacggtaatg actggcaaca caacggcgac aacatcaata tcgacgtcaa
    10861 caatttcaac cgtatcaccg gtgagcatct tactgataag aatatggcat ggcggcacaa
    10921 tccaaactac cgtaatggtg tgacctatca tgatcaggat atggcaaagc ggtttcatca
    10981 aaccgatgtc aacggcggaa tgagcgccac gcagttacct gctctatcgc gcgacagcca
    11041 gcgtcaggcg gcagcaagtc agtttcagca acgaacacac gccgcccccg tcattacgcg
    11101 agatacccaa cgtcaggcag cggcacagcg gtttaatgaa gcggaacact atggcaatta
    11161 tgacgacttc cgcgagttca gccgccacca accactgacc cagcagcaaa aggacgccgc
    11221 tcgccagcgt tatcagtctg cctcacctga gcagcgccag gcggcccgtg agaaaatgca
    11281 gactagcccg cagaatcaac agcaaagaga tgcagcacgt cagcgtattc agtccgcgtc
    11341 gcctgagcag cgccaggtgt ttaaggaaaa agtacagcag cgcccactga accaagagca
    11401 acgtgataac gcccgccagc gtgttcaatc ggcatcacct gaacaacgtc cgttttttcg
    11461 ggagaaagtt caggagagcc gcccgcaacg tctaaacgac agtaaccgta ctgccaggct
    11521 gaataacgag cagcggtcag cagtacgcga acgtctctct gaacgtgggg caagaagact
    11581 ggaaaggtaa attgcagacg taaaaaaagc ggcgtggtta gccgcttttt taattgccgg
    11641 atgttccggc aaacgaaaaa ttacttcttc ttcgctttcg ggttcggcag gtcggtaatg
    11701 ctaccttcga acacttctgc cgccaggccc acagactcgt gcagagtcgg gtgcgcatgg
    11761 atggtcagtg cgatgtcttc agcgtcacaa cccatttcga ttgccaagcc gatttcaccc
    11821 agcaactcgc cgccgttagt gccgacaatc gcaccaccga tcacacggtg agattctttg
    11881 tcgaaaatca gcttggtcat accgtctgcg cagtcggaag cgatagcacg accagaagca
    11941 gcccacggga aggtggcggt ttcgtagctg atgcctttct ctttcgcttc tttctcagtc
    12001 agacctaccc atgcaacttc tggttcggta taggcgatgg acgggataac tttcggatcg
    12061 aagtaatgtt ttttaccggc gataacttca gcggcaacgt gaccttcgtg aacacctttg
    12121 tgtgccagca ttggctgacc gacgatatcg ccgatagcaa agatgtgcgg tacgttggta
    12181 cgcagctgtt tgtcaacgcg gatgaaacca cggtcgtcaa cttccacgcc agctttgcct
    12241 gcgtcgaggt ttttaccgtt cggcacacga ccaatcgcta ccagcacggc gtcgtaacgc
    12301 tgcggttcag cgggtgcttt tttgccttcc atcgtcacat aaatgccgtc ttctttcgct
    12361 tcaacggcgg taactttggt ttccagcatc aggttgaatt tcttgctgat acgcttggta
    12421 aagactttaa cgatgtcttt atcagctgcc gggatgacct ggtcgaacat ttcaaccacg
    12481 tcaatctgtg aacccagcgc gtggtatacg gtgcccattt ccagaccgat gataccgcca
    12541 cccattacca gcaggcgttc tggtacttct ttcagttcca gcgcgtcagt ggagtcccag
    12601 atacgcggat cttcatgcgg aataaacggc agttgaatcg ggcgagaacc cgctgcaatg
    12661 atcgcgttgt cgaagttgat cacggtttta ccgttctcac cttcaacttc cagggtgtta
    12721 gccccggtga atttacccag accgttgacc actttgactt tgcggccttt cgccatacca
    12781 gccagaccac cggtcagctg attgatcact ttctctttcc aggtacgaat cttgtcgata
    12841 tcggttttcg gttcgccgaa gacgataccg tgttcagcca gcgctttggc ttcttcgata
    12901 acttttgcta cgtgcagcag tgctttagaa gggatacagc cgacgttcag gcaaacaccg
    12961 ccaagggtgt tgtaacgttc tacgattacg gtttccagac ctaaatcagc gcaacggaag
    13021 gcagcggagt aacctgcggg gcctgcccca agtaccacga cctgagtttt gatttcagta
    13081 ctcatcatga cctctatata tttatctccg gcgggtctga cgtttttttt atgacgccca
    13141 ttatccaccg ggtcgttcta tccgtcggta ttttacaaaa ttgttaacaa tttttaaaca
    13201 acaaacggca accgatttgt ctattcgcta ataacctcaa tacattcatg agattaccag
    13261 aaaaaagccg gccgttgggc cggctctttt acttacatca ccagacggcg aatgtcagac
    13321 agcgtgttgt taatgatggt aatgaaacgg gcaccatcag caccgtcgat cacgcggtgg
    13381 tcgaaggaga gagaaatcgg cagcatcaga cgcggcacga actctttacc attccacacc
    13441 ggctccatcg cggacttgga aacgccgagg atagccactt ccggcgcatt cacaatcggc
    13501 gcgaagtggg tagtacccag gccgccgatg ctcgagatgg tgaagcaacc gccctgcatt
    13561 tcgcccgcag tcagcttacc gtcacgcgct ttcttagaaa tagtcatcag ctcgcgagac
    13621 agctcgatga tgcctttctt gttgacgtct ttgaataccg ggacaaccag accgttcggg
    13681 gtatccaccg ccacaccgat gttgatgtat ttcttcaggg tcagacgctg accgtcttcc
    13741 gacagcgaac tgttgaagcg aggcatctgc tcaagagctg cagcaacggc tttcatgatg
    13801 aagacaaccg gggtgatctt cacatccagc ttacgtttcg ctgcttcttc gttctgctgt
    13861 ttacggaacg cttccagctc agtgatatcg gttttgtcga agtgagtaac gtgcgggatc
    13921 atcacccagt tacggctcag gttagcacca gagattttct gaatgcggcc cagttccact
    13981 tcttcgattt caccaaactt gctgaagtcc actttaggcc acggcagcat gcctgggata
    14041 ccgccgccag ttgccgccgg agctgcttct gcacgtttga ttgcttcttt cacgtaagcc
    14101 tgaacgtctt cgcgcaggat acgaccttta cggccagtgc ccttcacttt cgccaggtta
    14161 acgccaaact cgcgtgccag acggcggatc agcggagtcg cgtgaacgta agcgtcgttt
    14221 tcagcaaatt cagatttgcc ttcggctttc gcagccggtg ctgctgccgg ggcttcagct
    14281 tttgctgccg gagccggcgc tgccgcttcc tgtttcgcag gagctgccgc aggcgctgcg
    14341 ccttcaactt cgaagatcat aatcagcgaa ccagttttca ctttatcgcc aacgttgact
    14401 ttcagttcct tcacgacgcc tgcaaacgga gccggaactt ccatagaagc tttatcgcct
    14461 tctacggtga tcagtgactg ttcagcggca actttgtcgc ccactttcac catcacttcg
    14521 gtcacttcaa cttcgtcacc gccgatatcc ggaacgttaa cttctttcac gccagctgct
    14581 ggtgcagagg ccgctgccgg agccgcttcc tgtttagccg ccggagctgc cgcgccagct
    14641 tcacccgcga cttcgaagac cataatcagc gagccggtag acactttgtc acccacgttc
    14701 actttgatct ctttcacggt acctgcaaac ggagccggaa cttccataga agccttgtcg
    14761 ccttctacgg tgatcagcga ctgttcagct tcaactttgt cgcccacttt gaccaggatt
    14821 tcggtcactt caacttcgtc gctgccgata tccggaacgt taacgtcttt tgccgctgca
    14881 gccgctggtg ctgctgccgg agcggcttct ttcttctctt ctgcctgagc aggtgcagcg
    14941 tctgctgcac cgtcggcgga atcgaaaatc ataatcagtg cgccggtctg ggttttatcg
    15001 ccaacagaga ctttgatctc tttaacgata cccgcctgcg gagatggtac ttccatagag
    15061 gctttgtcgc cttctacggt gatcagcgac tgttcggctt caactttgtc gcccactttg
    15121 accaggatct cggtgatttc aacttcatca gccccgatgt ccggtacttt gatttcgata
    15181 gccattattc ttttacctct tacgccagac gcgggttaac tttatctgca tcgatgttga
    15241 atttggcgat tgcgtcagca accactttct tatcgatttc gccacgttta gccagttcgc
    15301 ccagcgccgc aaccacgaca taagaagcat caacttcaaa gtggtgacgc aggttctcac
    15361 ggctgtcgga acgaccgaag ccatcagtac ccagtacgcg gtagtcgtca gccggtacgt
    15421 aagtacggac ctgctcagcg aacagtttca tatagtcggt agatgccact gccggagcgt
    15481 cgttcatcac ctgagcgata tacggaacgc gcggagtttc cagcgggtgc agcatgttcc
    15541 agcgttcaca atcctgacca tcacgcgcca gttcggtgaa ggaagtcacg ctataaacgt
    15601 cagaacctac gccgtaatct ttcgccagga tctctgccgc ttcacggacg tgacgcagga
    15661 tagaaccgga gcccagcagc tgaactttac ctttgctacc ttcaatggtt tcgagtttgt
    15721 agataccttt acggatacct tcctcagcac cttccggcat tgccggcatg tggtagtttt
    15781 cgttcagcgt agtgatgtag tagtaaacgt tctcttgttt ttcaccgtac atacgctcca
    15841 gaccgtcatg catgatgaca gcaacttcgt aagcgtaagc cgggtcgtaa gagatacagt
    15901 tcgggatagt cagcgactga atatggctgt gaccatcttc gtgctgcaga ccttcaccgt
    15961 tcagggtggt acgaccggaa gtaccgccga tcaggaagcc acgcgcttgc tggtcgccag
    16021 ccgcccagca cagatcgccg atacgctgga aaccgaacat cgagtaatag atgtagaacg
    16081 ggatcatcgg cagattgttg gtgctgtaag aggtcgccgc tgccagccag gaacaacctg
    16141 cgcccagctc gttgatccct tcctgcagaa tctgaccttt ctcgtcttct ttatagtaag
    16201 caacctgctc gcggtcctgc ggggtgtact gctgaccgtt cgggctgtaa ataccaatct
    16261 gacggaacag accttccata ccgaaggtac gcgcttcgtc ggcgatgatc ggtaccagac
    16321 gatctttgat cgacttgttc ttcagcatca cgttcagagc acgaacgaaa gcgatagtgg
    16381 tagagatctc tttgctctgc tcttccagca gcgcgccgaa atcttgcagg ctcggcagct
    16441 ccagcttctc ggtgaagttc ggctggcggc ttggcagata accgtgcagt ttctgacgtt
    16501 gagcgtgcag ataggtatgc tcttcagaac cttccgggaa ggtgatgtac ggcagttttt
    16561 cgatatctgc atcagacacc ggcacattga aacggtcgcg gatgtgacgc acgccgtcca
    16621 tgttcatttt cttaacctgg tgcgcgatgt ttttaccttc agccgcgtcg cccatgccgt
    16681 aacctttaat ggtatgagca aggattaccg tcgctttgcc tttggtttcc tgcgctttct
    16741 tgaatgcagc gtagattttc ttcggatcgt gaccaccacg gttcagtgcc cagatctgct
    16801 cgtcagtcca gtctgcaacc agtgctgcgg tttcaggata tttaccgaag aagtgttcgc
    16861 gaacatacgc accatctttc gatttgaagg tctggtaatc gccgtcaacg gtttcgttca
    16921 tcagctggat cagtttaccg ctggtatctt tacgcagcag ttcgtcccaa cggctacccc
    16981 acatcacttt gatcacgttc cagccagcac cttcgaagat gccttccagt tcgttgatga
    17041 tcttgccgtt accggtgacc gggccgtcaa gacgctgcag gttacagttg ataacgaaga
    17101 ccagattatc cagtttttca cgggtagcga tggtgatcgc acctttggat tccggttcgt
    17161 ccatttcacc gtcgccgagg aacgcgtaaa cggtttgttt agaggtatct ttcaggccac
    17221 ggtgttccag atatttcagg aatttagcct ggtaaatagc accaatcgga cccagcccca
    17281 tagatacggt cgggaactgc cagaattccg gcatcagttt cgggtgcgga taggaagaga
    17341 ggccattgcc gtgaacttcc tgacggaagt tatccagctg ctcctgagtc agacgacctt
    17401 ccaggaaagc acgagcgtaa acgcctgggg agatgtggcc ctggaagtaa accaggtcgc
    17461 cgccatcctg ctcgttgcgt gcacggaaga agtggttaaa gcacacatca taaatggttg
    17521 cggaagactg gaaggacgcc atgtggccgc ccagttcgag gtcttttttc gacgcacgca
    17581 gcaccgtcat gatggcgttc cagcggatag ctgaacgaat acggcgttcc agttccagat
    17641 tacccggata ctccggttgt tcttcaacgg ggatggtgtt gatgtagttg ctgataccgg
    17701 tgcctgcagc tacgttgact ccgcctttgc gggcttcagc aagcagttgg tcgatcagat
    17761 actgagcacg ctcaacacct tcttcacgga tgaccgattc gatcgcctgg agccagtcgc
    17821 gagtttcgat cggatccacg tcatttggga aacgttctga catgggttat tccttatcta
    17881 tctaataacg ttgagttttc tggaacctgt cccattgaac tctcgccgga aagctcaata
    17941 agacaggttc tacgtttagt tgccgcgctt ttatatgcgc ttgatttaca acatcttctg
    18001 gataattttt accagaaaaa tcactaattc tttcgttgct ccagacgacg cagagaacgc
    18061 tcacggcggc tctcttcacg gcttctgtcg agcaaaattt cttcgataaa ggccagatgg
    18121 cgatgcgatg cttcgcgcgc ttcttccggc ttaccggcca taatcgcttc aaatatgcgg
    18181 gtgcggtgac tactcaccag cggcagcatc tcgcgacgcg aatagagcaa ttcgaagttc
    18241 tggcggacat tctgagccaa catcggctcc atacacctta gcagatgaag cagaaccaca
    18301 ttgtgggccg cttcggtgac ggcaatctga tactggagta cggcatttga ttccgcgtcc
    18361 agatcgccag actgctgcgc cagctctatg gcatggtgga gttcacggat gcgttccttg
    18421 tcttcatcgg tactacgcag cgcggcgtaa taagcggcga taccttccag ggcgtgtcgt
    18481 gtttcgagca agtcatactg tgattcagga tggtcggaga gcagctccac cagcggatcg
    18541 ctgaagcttt gccagaggct gctctggaca aaagtgccgc caccctggcg acgaagcaac
    18601 aagcccttcg cttcgaggcg ttgaatcgcc tcacgcaaag agggacggga gacgtcgaac
    18661 tgttttgcca gttcgcgttc cggtgggagt ttttcgcccg ggcggagagt gccttcgagg
    18721 atcaaaaact ccagttgctg ctcaatcaca tcggagagtt ttggttggcg gattttgctg
    18781 taggccatga gttcctgtct taagccactt gccgaagtca attggtctta ccaatttcat
    18841 gtctgtgacg ctaaagtaac aaagtattca ccttatgtcc atacaggttt tgattgaaat
    18901 catgaaactg tgcacatttt aacaacttga catatataac gtttcaaagt tgtaactatg
    18961 cacaaatgtt aaatttaccc atcaaggggt gaccttaaca gaattgaaac gaaaaaatat
    19021 ttcctctgaa ccgattcacc aagcaacaaa acgcataaca attcaattat gtgaattaat
    19081 atgtaaaatg aatgttcagg gaaggagaga aaggtagtat ttacctatgt tttcttttta
    19141 cattgcttat tatcactgca atcgccacca taaccttctc gtagcgaaaa tcatcactta
    19201 accagaacgt gatgattttc aggtgacaga ttctgtttag agttcattct gaatctttga
    19261 acaaaggcaa tccttgcgaa cgccgccatt ctttgacgat tttcaggatg ttttcaggtt
    19321 catcatctcc cttctttgca ggatagtaga taagatcgct catcaacgga tgttgtgtaa
    19381 ttctggtaag atgttcttct aga
//
LOCUS       DAFGPF010000090        19100 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFGPF010000090 DAFGPF010000000
VERSION     DAFGPF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19100
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.090"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1388)
                     /locus_tag="LSX49_003614"
     CDS             complement(<1..1388)
                     /locus_tag="LSX49_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBL7169975.1"
                     /translation="MQKTLMASLIGLAVCTGNAFSPALAAEAKQPNLVIIMADDLGYG
                     DLATYGHQIVKTPNIDRLAQEGVKFTDYYAPAPLSSPSRAGLLTGRMPFRTGIRSWIP
                     SGKDVALGRNELTIANLLKAQGYDTAMMGKLHLNAGSDRTDQPQAQDMGFDYSLVNTA
                     GFVTDATLDNAKERPRYGMVYPTGWLRNGQPTPRADKMSGEYVSSEVVNWLDNKKDSK
                     PFFLYVAFTEVHSPLASPKKYLDMYSQYMSAYQKQHPDLFYGDWADKPWRGVGEYYAN
                     ISYLDAQVGKVLDKIKAVGEEDNTIVIFTSDNGPVTREARKVYELNLAGETDGLRGRK
                     DNLWEGGIRVPAIIKYGKHLPQGMVSDTPVYGLDWMPTLAKMMNFKLPTDRTFDGESL
                     VPVLEQKALKREKPLIFGIDMPFQDDPTDEWAIRDGDWKMIIDRNNKPKYLYNLKSDR
                     YETLNLIGKKPD"
     gene            complement(1409..2170)
                     /locus_tag="LSX49_003615"
     CDS             complement(1409..2170)
                     /locus_tag="LSX49_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7169976.1"
                     /translation="MSAKRRLLIACTLITAIYHFPAYSSLEYKGTFGSINAGYADWNS
                     GFVNTHRGEVWKVTADFGVNFKEAEFYSFYESNVLNHAVAGRNHTVSVMTHVRLFDSD
                     MTFFGKIYGQWDNSWGDDLDMFYGFGYLGWNGEWGFFKPYIGLHNQSGDYVSAKYGQT
                     NGWNGYVVGWTAVLPFTLFDEKFVLSNWNEIELDRNDAYTEQQFGRNGLNGGLTIAWK
                     FYPRWKASVTWRYFDNKLGYDGFGDQMIYMLGYDF"
     gene            2784..2936
                     /gene="mokC"
                     /locus_tag="LSX49_003616"
     CDS             2784..2936
                     /gene="mokC"
                     /locus_tag="LSX49_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HBL7169977.1"
                     /translation="MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
     gene            complement(3040..4170)
                     /gene="dnaJ"
                     /locus_tag="LSX49_003617"
     CDS             complement(3040..4170)
                     /gene="dnaJ"
                     /locus_tag="LSX49_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBL7169978.1"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(4259..6175)
                     /gene="dnaK"
                     /locus_tag="LSX49_003618"
     CDS             complement(4259..6175)
                     /gene="dnaK"
                     /locus_tag="LSX49_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBL7169979.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            6546..6950
                     /locus_tag="LSX49_003619"
     CDS             6546..6950
                     /locus_tag="LSX49_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HBL7169980.1"
                     /translation="MKSVITISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASIYFKATRSASQTLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            6976..7689
                     /gene="msyB"
                     /locus_tag="LSX49_003620"
     CDS             6976..7689
                     /gene="msyB"
                     /locus_tag="LSX49_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HBL7169981.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPERHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            7838..8404
                     /gene="satP"
                     /locus_tag="LSX49_003621"
     CDS             7838..8404
                     /gene="satP"
                     /locus_tag="LSX49_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HBL7169982.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGIFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(8439..9026)
                     /gene="mog"
                     /locus_tag="LSX49_003622"
     CDS             complement(8439..9026)
                     /gene="mog"
                     /locus_tag="LSX49_003622"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HBL7169983.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARREVSE"
     gene            complement(9141..10094)
                     /gene="tal"
                     /locus_tag="LSX49_003623"
     CDS             complement(9141..10094)
                     /gene="tal"
                     /locus_tag="LSX49_003623"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HBL7169984.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAVDQEKLEKMIGDLL"
     gene            10373..11803
                     /locus_tag="LSX49_003624"
     CDS             10373..11803
                     /locus_tag="LSX49_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBL7169985.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDANGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFAMLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNTPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPEIGRQLSPDAWDDVSQE"
     gene            11873..12649
                     /gene="yaaA"
                     /locus_tag="LSX49_003625"
     CDS             11873..12649
                     /gene="yaaA"
                     /locus_tag="LSX49_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBL7169986.1"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISSLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     gene            complement(12689..12985)
                     /locus_tag="LSX49_003626"
     CDS             complement(12689..12985)
                     /locus_tag="LSX49_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HBL7169987.1"
                     /translation="MKKMQSIVLALSLVLFAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPYGPPPSPRHNKHNDHRGDHRPGPDKHHR"
     gene            complement(13199..14485)
                     /gene="thrC"
                     /locus_tag="LSX49_003627"
     CDS             complement(13199..14485)
                     /gene="thrC"
                     /locus_tag="LSX49_003627"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBL7169988.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHGGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            complement(14486..15418)
                     /gene="thrB"
                     /locus_tag="LSX49_003628"
     CDS             complement(14486..15418)
                     /gene="thrB"
                     /locus_tag="LSX49_003628"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBL7169989.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICQLDTAGARVLEN"
     gene            complement(15420..17882)
                     /gene="thrA"
                     /locus_tag="LSX49_003629"
     CDS             complement(15420..17882)
                     /gene="thrA"
                     /locus_tag="LSX49_003629"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HBL7169990.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    complement(17909..18028)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            complement(17964..18029)
                     /gene="thrL"
                     /locus_tag="LSX49_003630"
     CDS             complement(17964..18029)
                     /gene="thrL"
                     /locus_tag="LSX49_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HBL7169991.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            complement(18243..18929)
                     /locus_tag="LSX49_003631"
     CDS             complement(18243..18929)
                     /locus_tag="LSX49_003631"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HBL7169992.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAYLEPAA
                     RWVAHGSGDIIDNIKVFKTLAESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPAKSDTTADQHQLQALRERAMTLLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
BASE COUNT         4599 a         4980 c         4561 g         4960 t
ORIGIN      
        1 atatctggtt ttttaccgat cagattaagt gtttcataac gatcagattt cagattgtag
       61 agatatttcg gtttattatt gcgatcgata atcatcttcc agtcaccatc acggatcgcc
      121 cattcatcgg ttggatcatc ctggaatggc atatcaatcc cgaaaattaa tggcttttcg
      181 cgtttcaatg ctttttgctc aagaacagga accagcgatt caccatcgaa agtacggtct
      241 gtaggtaatt tgaagttcat cattttcgct aaagtaggca tccagtccag accataaacg
      301 ggtgtatctg aaaccattcc ctgtggtaga tgtttaccat atttaataat ggctggaaca
      361 cgaattccgc cttcccaaag gttatccttg cgaccgcgta atccatccgt ttcccctgcc
      421 aaattcagct catacacttt gcgcgcttca cgcgttaccg gaccgttatc actggtaaaa
      481 ataacgattg tgttatcttc ttcacccaca gctttgattt tatccagcac ttttccaacc
      541 tgtgcatcca gatagctgat attggcataa tattccccca caccacgcca gggtttgtct
      601 gcccagtcgc cataaaataa atcaggatgc tgcttctgat acgcgctcat atattgtgag
      661 tacatatcga ggtatttttt gggcgaagcc agggggctat gcacttcggt aaaagcaaca
      721 tagaggaaga aaggcttgct gtcctttttg ttatccagcc agttgacgac ttccgaactg
      781 acatactcac cgctcatttt atcggctcgt ggagtgggtt gcccgttacg tagccagcct
      841 gtcgggtaaa ccatgccata acgcgggcgt tctttagcgt tatccagcgt ggcgtcggta
      901 acaaagcccg ccgtattaac cagtgagtaa tcaaagccca tatcttgtgc ttgtggctga
      961 tcggtgcgat cgctgcctgc attcagatgc agcttaccca tcattgccgt gtcgtaccct
     1021 tgcgctttga gtagattagc aatcgtgagt tcgttacgcc ctaaggcaac atctttgcct
     1081 gaaggaatcc atgagcgaat tccagtacga aatggcatcc ggccggttaa tagccctgcg
     1141 cgtgaaggtg aacttaaagg agcgggggca tagtagtcag taaatttgac cccttcctgg
     1201 gcaagcctgt cgatattagg tgttttaacg atctgatgac catatgttgc taaatcgcca
     1261 taacctaaat catccgccat aataatgact aaattaggtt gtttagcctc tgcggctaag
     1321 gcaggactaa aagcattccc tgtgcaaact gcaaggccga tcaaactggc cattaacgtt
     1381 ttctgcataa ttattccctg ataaaaaatt agaaatcata accaagcata taaatcattt
     1441 gatcgccaaa gccatcgtag cccagcttat tatcgaaata acgccacgtc acactggctt
     1501 tccagcgagg atagaacttc caggcaatag ttaaaccgcc atttaacccg ttccggccaa
     1561 attgctgctc cgtgtaagca tcgttcctgt ccagttctat ttcattccag ttagataaaa
     1621 caaatttttc gtcaaataac gtaaatggta atactgctgt ccagccaaca acataaccat
     1681 tccaaccatt cgtttgacca tatttagctg atacgtagtc accagattga ttatgtaatc
     1741 caatatacgg tttaaaaaag ccccactcgc cgttccagcc gaggtaaccg aatccataaa
     1801 acatgtccag atcgtcaccc catgagttat cccattggcc ataaattttg ccaaagaatg
     1861 tcatatcaga gtcaaagagt ctgacatgcg tcattactga aaccgtatga tttcgccctg
     1921 ctacagcatg attgagtaca ttactttcat aaaatgagta aaattctgct tctttaaaat
     1981 ttaccccaaa atccgcagtc actttccata cttcaccacg gtgagtgttt acaaatccac
     2041 tattccagtc tgcataaccc gcatttattg aaccaaaggt tcctttatat tctaatgaag
     2101 aatatgcagg aaaatgatag atagctgtta tcagggtaca cgcaataaga agtcgtcttt
     2161 tggcagacat ataatatgtt ctccattcat tgtttttatg attccatagg aattaataca
     2221 ccagacaatt catttttatt aagaatgacc aggccagtat atttaaagat gactatcgaa
     2281 gcgtgatgaa gatcgcagat tacttttgcg aacgggcgga gggatatcgt gtttcagaaa
     2341 atgtgtctgt tttaaatatc accctttgat ttataggcat ttttcatgat gaacttagca
     2401 ttggctgctg aacgtatttc tttgtctctc tatagtatta cactaacctt taataattaa
     2461 tttcctttag ccattcactt ttgatagagg aaaacacctt ttttgtgaat ccctggatat
     2521 atttaagtta aataaattga tgtattgaaa tattattccg caaaaatgcg aggcgtcttc
     2581 agaaaaagaa ttgataaaac agaagtgaat taaaagcgca gtataatagc ggcgggtgct
     2641 tgaggctgtc tgtctcaggc attggctgaa cggcagatag agaaaagccc cgagtgatat
     2701 tttaccatca acccgaggcc ccctatatgc agaacacatg tagagtgcct cttactgacc
     2761 gaaaggtcaa ggagaagaga gcaatgaagc agcataaggc gatgattgtc gccctgatcg
     2821 tcatctgtat caccgccgta gtggcggcgc tggtaacgag aaaagacctc tgtgaggttc
     2881 acatccgaac tggccagacg gaggttgctg ttttcacggc ttacgaatcc gagtaagagc
     2941 aacggcgggg agtgatcccc gccactttac aggtgctcgc atatcttcaa cgcacccttt
     3001 tttttacctg gcctgcccac gggcaggctt ttggggaggt tagcgagtca ggtcgtcgaa
     3061 aaacttcttc acaccatcaa agaagctctt tgagcgcggg ctgttgtgct cgccggttgg
     3121 gccaccaaag ctttcttgca gctcttgcag cagctgtttc tgcttctcgt tcaggcctac
     3181 cggtgtttcg acgacaacgc ggcacagcaa atcaccctgt gcgccgccgc ggacagactt
     3241 gacgccttta ccacgcatac ggaacagctt accggtctgg gtttcgccag gaactttcag
     3301 tttaacgcga ccatcaaggg tcggcacttc gatttcgccg cccagcgccg ccatagcgaa
     3361 gttgatcggg acttcgcaat acaggttgtt gccttcacgc tcgaaaatcg ggtgctgttt
     3421 aacctgaacc tgaacgtaca ggtcgcctgc cggtgcgccg tgttcgcccg cttcaccttc
     3481 gcccgcaaga cggatgcggt ctccagtgtc cacccctgcc gggattttaa cggacagcgt
     3541 tttgctgcgc tcaacacgac catgaccatg acatttgttg cacggatctt tgatcagcgt
     3601 accgcggccc tgacagtgtg gacaggtctg ctgcacggca aagaaaccct ggcgcatctg
     3661 cacctggcca gaaccatgac aggtcggaca ggtctgcggc tgtgtacctg gttttgcacc
     3721 gctaccgtgg caaacgtcac actcttccag agtcggaatg cggatctctt tggtcacgcc
     3781 acgtacagct tcttcgaggg tgagctccat gttatagcgt aaatcagcac cgcgcgccgc
     3841 acgttgacga ccacgtccgc cgccaaaaat atcgccgaaa acgtcaccaa aaatatcgct
     3901 gaagtctgcg ccgccgccaa aaccgccgcc gcccatgccg ccttgctcaa acgcagcatg
     3961 accatactga tcgtatgccg cacgtttttg cgagtcggtc agaacttcat aagcttcctt
     4021 gatctcttta aatttcgcct cggcctcttt gtcaccctgg ttacggtccg ggtggtattt
     4081 catggccagg cgtttgtagg cctttttgat ttcacgctct tccgctgttt tggaaacgcc
     4141 taaaatctcg taataatctt gcttagccat cttttttgat ttgcccctag atgaatgcac
     4201 gggcggagag gaaattcccc ttcgcccgtg tcagtataat tacccgttta tagggcgatt
     4261 attttttgtc tttgacttct tcaaattcag cgtcgacaac atcgtcatct ttcgcgttgt
     4321 ttgcagaagc atcagcaccg gcagtctgct gctgggcatg ttgctgctgg gcgatttcca
     4381 tcagtttctg ggaaacctgt gccagttcct gcattttcgc ttcgatagcg gctttgtctt
     4441 cacctttcag agcagtttcc agtgcagtca gcgcagactc gatagcagtt ttgtcgtcag
     4501 ccggcagttt gtcgcctgct tcttcaacct gcttacgggt gctgtgcagc agatggtcgc
     4561 cctggttgcg agtctgtacc agctcttcaa acttacggtc agcttcggcg ttagcttctg
     4621 cgtcgcgtac cattttctgg atttcatctt cgttcagacc agaagaagcc ttgatagtga
     4681 tcttctgctc tttaccgctg tttttgtctt tcgcggaaac gtgcaggata ccgtcagcat
     4741 cgatatcgaa ggtaacttcg atctgcggca tgccgcgcgg tgccgggttg ataccatcca
     4801 ggttgaactg acccagagat ttgttatcag ccgcacgttt acgttcaccc tgcagcacat
     4861 ggatggttac cgcagactgg ttgtcttcag cggtagagaa cacctggctg tgcttggtcg
     4921 ggatagtggt gtttttcgcg atcagcgtgg tcatcacacc gcccatggtt tcgataccca
     4981 gagacagcgg ggtaacgtcc agcagcagta cgtcttttac gtcaccagtc agaacaccac
     5041 cctgaacagc agcaccgatg gctacagctt cgtccgggtt aacatcttta cgcggctctt
     5101 taccaaagaa ttcagcaact ttcttctgaa ccattggcat acgagtctga ccaccaacga
     5161 ggataacgtc gtcgatatca gatacggaca ggccagcgtc ctgcagtgca actttcagcg
     5221 gctcaatgga acggtttacc agatcttcaa ccaggctttc cagtttcgca cgagtcactt
     5281 tgatgttcat gtgtttcgga ccggtcgcgt ctgcagtgat gtacggcagg ttaacgtcgg
     5341 tctgctgagc ggaagacagt tcgattttcg ctttttctgc cgcttctttc aggcgctgca
     5401 ttgccagcgg atcgttgcgc aggtcaatgc cctgatcttt cttgaattct tcaaccagat
     5461 agttgatcag acggctgtcg aagtcttcac cacccaggtg ggtatcaccg ttggttgcca
     5521 gaacttcgaa ggttttttcg ccgtcaactt cgtcgatttc gataatggaa atatcgaaag
     5581 taccaccacc caggtcataa accgcgatag tacggttgcc agtacctttg tccagaccgt
     5641 aagccagcgc agctgcggtc ggttcgttga tgatacgttt tacttccaga ccagcgatac
     5701 ggcctgcgtc tttggttgcc tgacgctgag catcgttaaa gtatgccggt acggtaataa
     5761 cagcttcagt taccggttca cccaggtaat cttcagcggt tttcttcatt tttttcagca
     5821 cttcagcaga gatctgcggc ggtgccattt tctggccttt aacttcgacc catgcgtcgc
     5881 cgttatcagc agcaataatt ttgaacggca tgatggaaac atcacgctgt acttcttcgt
     5941 cctggaagcg gcggccaatc aggcgtttaa tcgcaaacag ggtgttttgc gggttcgtca
     6001 ctgcctgacg tttagccggc tgaccaacca gagtttcacc atcctgggta taggcaatga
     6061 tagaaggcgt ggtgcgatcg ccttcggcgt tctccagtac acgaggagtg gtgccatcca
     6121 taatcgctac acaagagttg gtagtaccca ggtcgatacc aattatttta cccatctaaa
     6181 cgtctccact atatattcgg tcatcatgtg gttgtgagtc tgtaataggg gcgaaacgtc
     6241 tggtttcaac tgcccaattt catttttttg cagactcact cactgcggtt gactactaaa
     6301 tggggtcgta acccacgtca tcaaggggga gatgcaaaaa ttttttgtgc ttttgcgcag
     6361 aaatttcgcg atatggcagg acaagacgtg aaactgacag caattttatt catataaaga
     6421 atgaatcgca gcaaggcatt catcaaaaaa ttgtaataaa aagaaaatat tacgtgcctg
     6481 aaacttctct ttatcagcgg taaactagtt tcatcccctt acccctcccc accaagagaa
     6541 tccttatgaa atccgttatt acgatttccg ccagcctggc gattagcctg atgctgtgct
     6601 gcacggcgca ggcaaacgac cataaaatcc tcggcgtcat tgcaatgccg cgaaacgaaa
     6661 ccaacgatct ggcgctgaaa cttcctgttt gtcgcattgt taaacgcata caactctcag
     6721 ccgaccatgg cgatttgcag ttaagcggtg catcgattta tttcaaagcc acccgaagcg
     6781 ccagtcagac cctgaatatt ccttcagaaa taaaagaagg gcaaaccact gactggatca
     6841 acattaacag cgataacgac aacaaacgct gcgtctcaaa aatcaccttt tccggtcata
     6901 cagtgaactc atcggatatg gccacgctga aaattatcgg cgacgactaa cgccagaata
     6961 tagaaaccac aaaaaatgaa tgttaattac ctgaatgatt cagatctgga ttttctccag
     7021 cattgtagtg aggaacagtt ggcaaatttc gcccggctgc tcacccataa tgaaaaaggc
     7081 aaaactcgcc tctccagcgt actgatgcgc aacgaactgt ttaaatcgat ggaaggacat
     7141 cccgagcgac accgccgcaa ctggcagctg attgccggag aattacagca ttttggtggc
     7201 gatagtatcg ccaacaaact gcgcggacac ggtaaattgt atcgcgccat tttgctcgat
     7261 gtttcaaagc gattgaagct gaaagccgac aaagagatgt ctacgtttga aattgagcaa
     7321 cagttactgg aacaatttct gcgtaatacc tggaagaaaa tggacgagga acataagcag
     7381 gagtttctgc acgcggtcga tgccagggtg aatgagctgg aagagctgct gccgctgctg
     7441 atgaaagaca aattattggc aaaaggtgtg tcgcatttgc tttccagcca attgacccgc
     7501 attttacgca cccacgcagc aatgagcgtg cttgggcatg gtttgctgcg cggcgcgggt
     7561 ctgggaggcc ctgtgggcgc agcattaaat ggggttaaag cggtcagcgg cagtgcctat
     7621 cgcgtgacaa ttccagccgt actgcaaatc gcctgcctgc gccggatggt tagcgccact
     7681 caggtctgat accggaaacc ggggaaaatt ttcattttcc cctcaaaaga tcgtagacac
     7741 tgccccactg gctgattatt atgccgcgcc ctgaaaacac tacagttatt cagggaaatt
     7801 atttcaccat tcattcgatg atgatttttg aggaattatg ggcaacacta agttggctaa
     7861 tccggcaccg ctgggcctga tgggcttcgg catgaccacc attctgctta acctgcacaa
     7921 cgtgggttat tttgctctgg acggtattat tcttgccatg ggcattttct acggcggcat
     7981 cgcgcaaatt tttgccggtc tgctggagta caaaaaaggc aacactttcg gtttaaccgc
     8041 attcacctct tacggttctt tctggctgac gctggttgca attctgctga tgccgaaact
     8101 ggggctgacc gatgcgccaa atgcacagtt ccttggtgtc tacctgggtc tgtggggcat
     8161 atttacgctg tttatgttct tcggcacgct gaaaggcgca cgcgttctgc aattcgtttt
     8221 ctttagcctg accgtgctgt ttgccctgct ggcgatcggt aacattgccg gtaacgccgc
     8281 gatcatccac tttgccggct ggattggtct tatctgcggt gccagcgcaa tctatctggc
     8341 gatgggtgaa gtgctgaacg agcagtttgg tcgcaccgtt ctgccgattg gtgaatccca
     8401 ctaattgttt tgagatcccc ccgctcgggg ggattttttt attcgctaac ttcgcgtctt
     8461 gcactcttcg gtctgaatgc tgcaaccact tccggtgccg tttcaacgta tggcccttcc
     8521 agcaactgaa tgcagtacgg tacgctggca aaaataccgt gcaccacaac gttaccctca
     8581 gcgtccttca caccttccag cgtctcttta atagacttcg gttgaccggg taagttaagg
     8641 atcagcgcct gtttgcgaat cacccccacc tgacgcgaaa ggatcgcagt tggtacaaaa
     8701 tgcaggctga tctggcgcat ctgttcacca aagcctggca tctcgcggtc cgctactgcc
     8761 agcgtcgcat cgggcgttac gtcacgacgc gccgggccag ttccgcccgt ggtaagcacc
     8821 agatggcaac tcatttcatc caccagctca cacaacgttt gctcgatgat cgcctgctca
     8881 tcgggaatta agcgggtttc cagttcaaac ggcgtggtta gcgccgatgt cagccattct
     8941 tccagcgcag ggatgccttt atcctgataa acgccgctgg atgcgcgatc agagatggaa
     9001 actaagccaa tacgtaaagt attcatcaag atttttccgt ttaaacagtc tcgttaaaca
     9061 gaatgataca ctgcgaaggg agtgacagac aggtttcaga agaggtagcg tgaccgactt
     9121 cccggtcacg ctaagaatga ttacagcaga tcgccgatca ttttttccag tttttcctgg
     9181 tcaacagcaa acttacggat accttccgcc agtttatcta ctgccattgg atcctggttg
     9241 tgctgccaca ggaactcgga ctcagtgata cgcgccggac gcgctttcac ttcaccagtg
     9301 taagacagtt tacgttcgat agccccttcg ctctccgcca gctctttcag cagtgccggt
     9361 gcgatggtca gacggtcgca gcctgccagt tccagaattt cgccgatgtt acggaagctt
     9421 gcgcccataa ccacggtttc ataaccgtgc tctttgtagt actggtagat ttcagataca
     9481 gaaaccacgc ctggatcttc tgccggagcg tactctttct tatcggtatt cgctttgtac
     9541 cagtcaagaa tacggccaac aaacggcgag atcaggaaca cgcccgcttc cgcacaagca
     9601 cgagcctgag cgaaggagaa cagcagggtc aggttacagt tgatgccttc tttttccagc
     9661 tgttccgcag cacggatacc ctgccaggta gaagccagtt tgatcagaat acgatcgttg
     9721 ctaatacctg catcgttgta gagtttgatc aggcgttttg ctttcgcaat tgacgcttcg
     9781 gtgtcatagg aaagacgcgc atcaacttca gttgagatac ggcccggaac cagtttcagg
     9841 atttccagac caatatttac ggccagtttg tcggtcgcgt ccacgatctg ctgcgcgcga
     9901 tcgttgctct gctgtttcgc ccaggcgaca gcatcatcaa tcaacttacg gtattccgga
     9961 atctgcgctg cgttaagaat gagagaaggg ttggttgtgg catcctgcgg ttgatacagc
    10021 ttcattgccg cgatgtcccc agtgtcggcc actacggtgg tgtactgacg aagggaggtc
    10081 aatttgtccg tcatgatagt atttctcttt aaacagcttg ttagggggat gtaaccggtc
    10141 tgccctgatg atatcacgac gcaacgtcag cgcaaccgcc gacaagacgg ttatcgccag
    10201 gcgagactgt ttcggatttc tgacactgcg ttgatatcgc ccgccatttt tatacaaaac
    10261 ctcatgtatg ctacgcagaa gttatcaagt acctcgtagc gtatatactt cttaaacaat
    10321 tggtaacgtt tacacaggaa agtcatcgcg accggcaata agagggatat gcatgccaga
    10381 ttttttctcc tttattaaca gcgtcctttg gggttcggta atgatttacc tgctcttcgg
    10441 cgcaggttgt tggttcactt ttcgcaccgg atttgtgcag tttcgctaca tccgccagtt
    10501 tggcaaaagt cttaaaaata gcattcatcc acagccaggc ggtttaacct catttcagtc
    10561 attgtgtacc agtcttgcag cgcgcgtggg tagcggcaac ctggccggcg ttgcgctggc
    10621 aattaccgcc ggtggacctg gagccgtctt ctggatgtgg gttgccgcat ttatcggcat
    10681 ggcgacctcg tttgccgaat gttccctcgc acagctttat aaagaacgtg atgccaatgg
    10741 gcagtttcgt ggcggaccgg catggtatat ggcgcgcggg ctggggatgc gctggatggg
    10801 cgttctgttc gccgtctttt tgctcatcgc ctacggcata attttcagcg gagttcaggc
    10861 gaacgccgtt gcgcgagccc tgagtttttc ttttgatttt cccccgctgg tgacaggtat
    10921 tattctcgct gtctttgcta tgctggcgat cactcgcggt cttcatggcg tcgcccggct
    10981 catgcagggg tttgtcccgt tgatggcgat aatctgggta ctgaccagcc tggtgatttg
    11041 cgtaatgaat atcgggcaac ttccccacgt catttggtct atttttgaga gtgcttttgg
    11101 ctggcaggaa gcggcaggcg gcgcggcggg atatacctta agccaggcga ttactaacgg
    11161 ttttcagcgc agtatgtttt ccaatgaggc gggaatgggg tcgacgccaa acgcggcagc
    11221 ggcagctgcg tcctggcctc cgcatccggc agcgcaagga attgtccaga tgattggcat
    11281 ttttatcgac accctggtca tctgtacggc aagcgccatg ctgatattac tggcgggtaa
    11341 cggcacaacc tacatgccgc tggaaggtat tcagcttatc cagaaggcga tgcgggtgct
    11401 aatgggttcc tggggtgcgg agtttgttac cctcgtggtt attctgtttg ccttcagctc
    11461 catcgttgcc aactacattt atgccgaaaa caatctcttc tttttacgcc tgaacacccc
    11521 taaagcgatc tggtgtctgc ggatctgcac cttcgcaacg gtcatcggcg gcaccttgct
    11581 aagtcttccg ctgatgtggc aactggcaga tatcattatg gcctgcatgg ctattaccaa
    11641 tttgaccgcc atattactgc tctcgcctgt ggttcatacc attgccagtg attatctacg
    11701 ccagcgtaaa ctcggcgtgc gcccggtgtt tgatccgttg cgttatccgg agatcggtcg
    11761 ccagctttct ccggacgcgt gggatgatgt ttcgcaggag taatcacaac tatcgatcaa
    11821 ctcattctct ttttttgcta aagtcggcat aaatttcctg caaggactgg atatgctgat
    11881 tcttatttca cctgcgaaaa cgcttgatta ccaaagcccg ttgaccacca cgcgctatac
    11941 gctgccggag ctgttagaca actcccagca gctgatccat gaagcgcgga aactgacgcc
    12001 cccgcagatt agctccctga tgcgcatcag cgataaactg gcgggtatca acgccgctcg
    12061 ctttcatgac tggcagccag atttcacacc ggaaaatgcc cgccaggcaa ttctggcgtt
    12121 taaaggtgat gtctacactg gcttgcaggc cgaaaccttc agcgaagacg atttcgattt
    12181 tgcccaacag catttgcgaa tgctttccgg cttgtatggc gtactgcgcc cgctcgattt
    12241 aatgcagcct tatcgtctgg aaatggggat acgtcttgag aatgcccgag ggaaagatct
    12301 gtatcaattc tggggagata tcatcaccaa caagctgaac gaggcgctcg cagcacaagg
    12361 cgataatgta gtgataaatc tggcgtcaga tgagtatttt aaatcggtga agccgaagaa
    12421 attgaatgcc gagattatca agccagtgtt cctcgatgag aagaacggca aatttaagat
    12481 aatcagcttc tacgctaaga aagcacgcgg tctgatgagt cgtttcatta ttgaaaatcg
    12541 gctgaccaaa ccagagcaac taactggttt taatagcgaa ggttacttct ttgatgaagc
    12601 ttcctccagc aatggcgaac tggtgtttaa acgctacgag cagcgttaag tttgtagtca
    12661 atgccggatg gcaatccggc attgatattt agcgatgatg tttgtcaggc cccggacgat
    12721 gatcgccacg atgatcattg tgcttgttat ggcgcggcga tggcggcggt ccatatgggt
    12781 gccagcgatt gcctcgccat tcataatgtt gtttccacca gccgtggtcg cgccagtgac
    12841 cgccatccca gtaatagcca cgattatcac gatcgcctat ctgtaatttt actgacggga
    12901 ctagcgtaat ttccgcagcc tgcgctgcca tgggagcgaa cagaaccagg gaaagtgcga
    12961 gtacgataga ttgcatcttt ttcacaggtt actcctttta tcattgcccg ttatgggtcg
    13021 atatccggag attacgcgat gagaacggca gttgttattc tccgcaatcc taatctctaa
    13081 gttaccgcat ttattgagaa tttctccttt ttccctgtcg tttttctcca tattttcttc
    13141 ataaaaaagc cgggctgcat aaaagcaaac ccggcctgat tgagataatg aatagatgtt
    13201 actgatgatt catcatcaat ttacgcaacg cagcaaaatc ggcgggcagg ttatgcgaaa
    13261 gcaagggtaa atcagcacgt tctgccagct cttttggcag atccaacgtt tcaccgagaa
    13321 tcgcttccac gctctcttta aattttgccg gatgcgcggt gccgaggaac aagccatatt
    13381 cgcctggatt caactggtca cgcagcgcac gataagctac ggcagcgtgc ggctccgagg
    13441 tatagcccag ttcttttaac tcacgcattg tctgttgcgt ggtttcatca tccacggctg
    13501 cataccccag ctctttcagt tgccagattt tgcggcggaa caactcttcc acacgcggcc
    13561 agttgtttgg ctggctaaca tccatcgcat tggataacgt cgcctgagtc gctttgggtg
    13621 accactgacc gccgtgcagg aaacgtggca cggtatcatt cacgttggtc gcagcaataa
    13681 aacgcttcac cggcaggcca agagatttcg ccagcaggcc cgctgtcaaa tcgccgaagt
    13741 taccgctcgg caccgagaca accagctggt tgcgcgcttc ctgcggcaac tgcgccacgg
    13801 cttcaaagta gtagcaaatc tgcgccagca aacggctgat gttaatggag ttagcagagt
    13861 ttagccccag cgccactttc agctcttcat catcaaacgc ctgcttcacc agcgcctgac
    13921 aggcatcgaa atcgccgtcg atggcaacag tttcgatatt gccgcccaat gtacagaaca
    13981 gtttttcttg cagtggactg attttgcctc gtggatagag gataaccact ttcacattcg
    14041 gtaaaccgta gaaagcatga gccactgccg ctccagtatc accggatgtc gcggtcagaa
    14101 tggtcactgg cttatcgccc gcaatatggg tcagcatttg tgccataaag cgaccgccga
    14161 aatctttaaa tgccagcgtt ggcccgtgga acaattccag acaaccgaca tcgctttcaa
    14221 cattggcgac cggagccggg aaggcaaacg ccgcacgtac gcgctcttcc aggatttcct
    14281 gcgggatttc atcaccaata aacgccgaga ggatcttcgc actgcgggtg acaaaatcca
    14341 gcttcagcat ctcatcaatt tcagtcaggc tgaattccgg caggtcgtgc ggaaaaaaca
    14401 gcccctgatt tttgcctaac ccctgggtta cggcttgcgc aaagctgacc tgctcattgt
    14461 gatctttcag attgtagagt ttcatttagt tttccagtac tcgtgcgccc gccgtatcca
    14521 gctggcaaat atgaacaaaa ccttcctgat tttgcaggta gttcttaccc aaccagtcgg
    14581 caacgcgctg agcggtatcc ggcttgtcac acagagcgaa caaggtcggg ccggagccgg
    14641 agataccgct cgcaaccgcg ccgatttccg caaccgcctg ccgcgcctgc cggaagccag
    14701 gcaataaccg ttcacggtag ggttcagcga taacatcttt catcagcttc gcggcaagct
    14761 caggctgacg ggaatagcag gcgtgaatga atcctgccaa atgtcgcccg tgcgcaatgc
    14821 aatcctggcg gcgatactgc gccggtaaaa tagcccgggc ttctgccgtc gagactttaa
    14881 tccccggata cgccagcacc cacagccact catcaaaccc tggcacttgc tgactgatga
    14941 tgtcgttttc ttcaatcatc aactgcatac caccaagaaa acacggtgcc acgttgtcgt
    15001 aatgaatgct gccggagata cgcccttcca actcgcccat caaagccagc aaacgagtgt
    15061 cattaagcgg cttgccgcag tgttcattca tcgccatcag cgccgcgacc actgaacagg
    15121 cgctggagcc taagcccgaa ccgatcggca tattcttttc cagagtcatc gccactggaa
    15181 tttgcttgcc aagctcctgg caaaaacgct cccagcactg ataaacgata ttttcccgtg
    15241 gctctgacgg cagcttatcg gcaaagcgtc cgaggttgtt gagactgaat gtctctgctg
    15301 cctcaaccgt gactacatct ccgagcaatg caccatcaac aggtgtcacc gccgccccga
    15361 gcacatcaaa cccgacgctc atattggcac tggaagccgg ggcataaact ttaaccatgt
    15421 cagactccta acttccatga gagggtacgt agcagatcag caaagacacc ggcagctgta
    15481 acgtcattgc ccgcaccata tccgcgcagt accaacggca gcggctgata atagtggcta
    15541 tagaaggcca gggcgttttc gccatttttc actttgaaca gcggatcatt accatccact
    15601 tcggcaatct tcacgcggca gacgccatct tcatcaatat tgccaacata gcgcaaaact
    15661 tttccttcat cacgagcctt cgccacacgc gcggcaaaga gatcgtcgag ctgtgacaga
    15721 ttcgccataa aagcggcaac atcaccctcg gcgttaaact ctgcgggcag cacaggttca
    15781 atttcaatat ccgccaactc cagttcacgt cccgtttcac gagcgagaat caatagttta
    15841 cgcgccacat ccataccaga aagatcatct cgcgggtccg gttcggtata acccatttcc
    15901 cgcgccagtg tggtcgcctc ggagaaactc atgccttcgt ctaacttgcc gaagatataa
    15961 gaaagcgaac ctgaaagaat gccggagaac ttcatcaatt catcaccagc attgagcaga
    16021 ttttgcaggt tctcaataac cggtaatcca gccccaacgt tggtgtcata gaggaattta
    16081 cgccgcgatt tttccgccgc ataacgcaac tgatggtagt aatccatcga cgaggtgttg
    16141 gcctttttgt tcggcgtaac aacgtggaaa ccttcgcgca ggaagtcggc atattgatct
    16201 gccacagcct ggctggaagt acagtcaaca atgaccgggt tcagcagatg atattctttc
    16261 acgaggcgaa ttaagcgccc gagattaaac ggctctttgg cttgcgccag ttcttcctgc
    16321 cagttttcca gattaaggcc atgtacattg gtgagcagtg ccttcgagtt agcaacaccg
    16381 cagacacgta agtcgatatg tttattcttc aaccagcttt gctgacgctt cagttgctcc
    16441 agcagcgcac cgccaacgcc accgacgcca atcacaaaca cttcgataac ctgatcggta
    16501 ttgaacagca tctgatgagt aacgcgcacg ccagtggtcg catcatcgtt attgaccacg
    16561 acagagattg agcgttcaga agatccctga gcaatggcga caatattgat gttggcgcgg
    16621 gccagcgcgg caaagaattt cgccgagatc ccacgtaagg tgcgcatacc atcacctacc
    16681 accgagataa tggccagccg ttccgtcacc gccaacggct ccagtaagcc ttctttcagt
    16741 tccaggtaga actcttcctg cattgcccgt tcagctcgca cacagtcgct ttgcggaacg
    16801 cagaaactga tactgtattc ggaagatgat tgcgtaatca gcaccacgga aatacgggcg
    16861 cgtgacatcg ctgcaaagac gcgcgccgcc atgccaacca tccctttcat ccccgggccg
    16921 gaaacgctga acattgccat gttattcaga ttggaaatgc ccttgaccgg taattcgtct
    16981 tcatcacggc tggcaccaat gagcgtacct ggtgcttgag gatttccggt atttttaatc
    17041 aggcaaggga tctggaactg ggcgatgggg gtaatggtgc gggggtgaag aactttagcg
    17101 ccgaagtaag aaagctccat cgcttcctga taggacatcg acttcaacaa cctcgcatcg
    17161 ggcacctgac gcggatcgca ggtataaaca ccgtcaacat ccgtccagat ctcgcaacaa
    17221 tcggcgcgta aacaggccgc cagcaccgca gcggagtagt cggaaccgtt gcgtcccaga
    17281 accaccagct cgcctttttc attaccggca gtgaaaccag ccatcagcac catgtggtca
    17341 gccggaatgc ggcttgccgc aatacggcgg gtggattcag caatatcaac ggtagattcg
    17401 aggtaatgac ccactgccag cagtttttcg accggatcga taacggtaac gttgtgacca
    17461 cgcgcttcta acacgccggc cataatggcg atcgacattt tctcgccacg gcaaatcagc
    17521 gcagcgttga tgctatccgg gcactgcccc aacaaactga tgccatgcag gacatgtttt
    17581 atttgggcaa attcctggtc gacgaaagtt ttcaattgtg ccagcggaaa tcccggctgg
    17641 gcggcggcga gtcccgtcag aagttcggca aaaatacgtt cggcatcgct gatattgggt
    17701 aaagcatcct ggccgctaat agttttttca atcatcgcta ccagatggtt ggtaattttg
    17761 gcgggggcag agaggacggt cgccacctgc ccctgcctgg cattgctttc cagaatatcg
    17821 gcaacccgca gaaaacgttc tgcatttgcc actgatgtac cgccgaactt caacactcgc
    17881 atggttgtta cctcgttacc tttggtcgaa aaaaaaagcc cgcactgtca ggtgcgggct
    17941 tttttctgtg tttcctgtac gcgtcagccc gcaccgttac ctgtggtaat ggtgatggtg
    18001 gtggtaatgg tggtgctaat gcgtttcatg gatgttgtgt actctgtaat ttttatctgt
    18061 ctgtgcgcta tgcctatatt ggttaaagta tttagtgacc taagtcaata aaattttaat
    18121 ttgatcacgg caggtaacca gttcagaagc tgctatcaga cactcttttt ttaatccaca
    18181 cagagacata ttgcccgttg cagtcagaat gaaaagctga aaatcactta ctaaggcgtt
    18241 ttttatttgg tgatattttt ttcaatatca tgcagcaaac ggtgcaacat tgccgtgtct
    18301 cgttgctcta aaagccccag gcgttgttgt aaccagtcga ccagttttat gtcatctgcc
    18361 actgccagag tcgtcagcaa tgtcatggct cgttcgcgta aagcttgcag ttgatgttgg
    18421 tctgccgttg tgtcactttt cgccggttgt tgtattaatg ttgctaattg atagcaatag
    18481 accatcaccg cctgccccag attgagcgaa ggataatccg ccaccatcgg cacaccagta
    18541 agaacgtcag ccaacgctaa ctcttcgtta gtcagcccgg aatcttcgcg accaaacacc
    18601 agagcggcat ggctcatcca tgaagatttt tcctctaaca gcggcaccag ttctactggc
    18661 gtagcgtagt aatgatattt cgcccgactg cgcgcagtgg tggcgacagt gaaatcgaca
    18721 tcgtgtaacg attcagctag tgtcttgaaa actttaatat tatcaataat atcaccagat
    18781 ccatgtgcga cccaacgggc ggctggctcc aggtacgcct gactatcgac aatccgcagt
    18841 tcgctaaaac ccatcgtttt cattgcccgc gccgctgccc caatattttc tgctctggcg
    18901 ggtgcaacca gaataatcgt tatacgcata ttgccactct tcttgaccaa ataaccgcga
    18961 acagggtgat caccgtcaac ttattacgcg gtgagaattt acaaattctt aacgtaagtc
    19021 gcagaaaaag ccctttactt agcttaaaaa aggctaaact atttcctgac tgtactaacg
    19081 attgaattgt taaaaaatgc
//
LOCUS       DAFGPF010000091        18988 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFGPF010000091 DAFGPF010000000
VERSION     DAFGPF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18988
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.091"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            186..956
                     /locus_tag="LSX49_003632"
     CDS             186..956
                     /locus_tag="LSX49_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HBL7169993.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNNGGWDGAVITFFASTTAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSDTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            947..1420
                     /locus_tag="LSX49_003633"
     CDS             947..1420
                     /locus_tag="LSX49_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HBL7169994.1"
                     /translation="MGVIEFLFALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            1527..2066
                     /gene="dnaT"
                     /locus_tag="LSX49_003634"
     CDS             1527..2066
                     /gene="dnaT"
                     /locus_tag="LSX49_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HBL7169995.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            2069..2806
                     /gene="dnaC"
                     /locus_tag="LSX49_003635"
     CDS             2069..2806
                     /gene="dnaC"
                     /locus_tag="LSX49_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HBL7169996.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            2855..3349
                     /locus_tag="LSX49_003636"
     CDS             2855..3349
                     /locus_tag="LSX49_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HBL7169997.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            3603..5894
                     /gene="opgB"
                     /locus_tag="LSX49_003637"
     CDS             3603..5894
                     /gene="opgB"
                     /locus_tag="LSX49_003637"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HBL7169998.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLTWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHVDKTTWKSKTAFKDTVIDMARYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(6034..7056)
                     /gene="lgoD"
                     /locus_tag="LSX49_003638"
     CDS             complement(6034..7056)
                     /gene="lgoD"
                     /locus_tag="LSX49_003638"
                     /EC_number="1.1.1.414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-galactonate oxidoreductase"
                     /protein_id="HBL7169999.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGNQPFFSYPRVLGHEICGEVVGLGKNVADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAETYERDVINNRELI
                     KGVITF"
     gene            7195..8109
                     /locus_tag="LSX49_003639"
     CDS             7195..8109
                     /locus_tag="LSX49_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313344.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL7170000.1"
                     /translation="MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTT
                     VRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQR
                     QLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIQSEKRGQWSMKQFDQSYAEQL
                     FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHS
                     LLLSAADNIFFEQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLD
                     ATLALRNHLNSAKQSMIRSINENMRYAH"
     gene            8326..9687
                     /locus_tag="LSX49_003640"
     CDS             8326..9687
                     /locus_tag="LSX49_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170001.1"
                     /translation="MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAM
                     LLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLD
                     RKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
                     IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYR
                     NREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLY
                     LAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKIC
                     IIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV
                     GSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDP
                     RKD"
     gene            complement(9736..11400)
                     /gene="tsr"
                     /locus_tag="LSX49_003641"
     CDS             complement(9736..11400)
                     /gene="tsr"
                     /locus_tag="LSX49_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HBL7170002.1"
                     /translation="MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQ
                     TIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAE
                     KNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
                     DGFEKQYVAYMEQNDRLHDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASL
                     VAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA
                     IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSAS
                     ETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQ
                     GRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVT
                     RVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRL
                     TEAVAVFRIQQQQQQQRETSAVVKTVMPAAPRKMAVADSGENWETF"
     gene            11777..13927
                     /gene="btsT"
                     /locus_tag="LSX49_003642"
     CDS             11777..13927
                     /gene="btsT"
                     /locus_tag="LSX49_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HBL7170003.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            13977..14180
                     /locus_tag="LSX49_003643"
     CDS             13977..14180
                     /locus_tag="LSX49_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HBL7170004.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            14191..15147
                     /gene="yjiA"
                     /locus_tag="LSX49_003644"
     CDS             14191..15147
                     /gene="yjiA"
                     /locus_tag="LSX49_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HBL7170005.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVISTKPRFHFIA
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK"
     gene            complement(15181..15483)
                     /locus_tag="LSX49_003645"
     CDS             complement(15181..15483)
                     /locus_tag="LSX49_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HBL7170006.1"
                     /translation="MSMVKHKRGTPSTLDVQHEAELKALANKFDEDIDYSDIPPSSDE
                     QWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLRDQNKK"
     gene            complement(15470..15757)
                     /locus_tag="LSX49_003646"
     CDS             complement(15470..15757)
                     /locus_tag="LSX49_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HBL7170007.1"
                     /translation="MPMEFEWDANKAKSNRVKHGIRFEDAVLVFDDPQHLSQQDRIEN
                     GEYRWQTIGLVHGIVVILVAHTIRFESGNEIIRIISARKADRKERSRYEHG"
     gene            15954..17120
                     /locus_tag="LSX49_003647"
     CDS             15954..17120
                     /locus_tag="LSX49_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HBL7170008.1"
                     /translation="MKNYKVITPLFPTYAQVKAMMKAVSGYSLKAVRNMITAIRDQTG
                     TPQKPVDWSEPDLWISERLTGEDADIARRIWDTDNHILNPRHSYGCYLFLNYPQFELM
                     ESTPDDTWQPTSRGQKFLQDDEKTLRSLDDQEGILQLLELLAGREMSRRADLLPEWQA
                     FLHQHSKFASASSVKSTLYSRLYNLIDRGMVTREGMSYCITDTGRAWLGKALPARKSD
                     PRKELLEAVKRYNEQQKELLREQISTMNPYKFEQLVGQLLEAMGYEQVEVTKASGDKG
                     VDVIGQVQVGITTITEVVQVKRMQNTITRPYIDQLRGALPYHKAIRGTLITTGKFAAK
                     CAEAALFPGAAPITLIDGDRLLELLIENNVGIRRSNAVELLDVDLQLFDELEMD"
     gene            17184..18803
                     /locus_tag="LSX49_003648"
     CDS             17184..18803
                     /locus_tag="LSX49_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003845607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL7170009.1"
                     /translation="MAKAPTKKAKAKKGFEETLWDTANQLRGSVESSEYKHVVLSLVF
                     LKFISDKFEARRKKMIADGQADFLEMEVFYQQDNIFYLPEEARWSFIKQNAKQDDIAV
                     RIDTALSTIEKRNPTLKGALPDNYFSRQNLETKKLASLIDTIDNIETLAHETDVETLS
                     KEDLVGRVYEYFLGKFAATEGKGGGEFYTPKCVVTLLTEMLEPFQGKIYDPCCGSAGM
                     FVQSVKFVESHQGKSRDIALYGQELTATTYKLAKMNLAIRGLSANLGERPANTFFSDQ
                     HPDLKADYILANPPFNLKDWRNEAELTEDPRFAGYRMPPTGNANYGWILHMLSKLSAN
                     GTAGFVLANGSMSSNTSGEGEIRAQMIENDLIDCMIALPGQLFYTTQIPVCLWFMTKS
                     KAADPAKGYRDRQGETLFIDARNLGTMISRTTKELTAEDIATIADTYHAWRSTPEELA
                     ARIARGDSKLEKYEDQAGFCKVATLQDIKDNDYVLTPGRYVGAAEQEEDGVAFETKMR
                     ELSKTLFEQMKQAEELDRAIRQNLEALGYGE"
     gene            18793..>18988
                     /locus_tag="LSX49_003649"
     CDS             18793..>18988
                     /locus_tag="LSX49_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000535012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL7170010.1"
                     /translation="MGSKWCIYRLGDIAEFSYGKMPKKEFVGTGDYVIFSGYKYTESY
                     PEKNTSAGELIVVARGVGGTG"
BASE COUNT         4611 a         4984 c         4754 g         4639 t
ORIGIN      
        1 tattcatgtg atagtttgtt tgcggcgaga gataattcgc tttttatcac cgagcttgtc
       61 ccgataacca ggattaatca gcgcaatttt gatcttaacc tacctcaaaa caaccgtgct
      121 tcatgataca aatggattct cattatctga acaatacgca gcacgtctat gacaaagggc
      181 gagttatgca aactgagcaa cagcgagccg taacgcggct ttgtatccag tgtggattat
      241 ttcttttgca acatggtgcg gaaagcgcgt tggttgatga gctttcctca cgactgggtc
      301 gggcgttggg aatggacagc gtcgaaagtt ctatctcttc gaacgccata gtgctgacaa
      361 ctattaaaga tgggcaatgc ctgacatcga cacgaaaaaa tcacgatcgc ggcattaata
      421 tgcatgtggt gactgaagtc cagcacattg tgattcttgc ggagcatcat ctgctggatt
      481 acaaaggcgt agagaaacga tttagccaaa ttcagccatt acgttaccca agatggctgg
      541 tagccttaat ggttggcctt tcttgcgcct gtttctgtaa actcaataac ggtggctggg
      601 atggtgccgt catcaccttc tttgccagta cgaccgcgat gtatatccgc cagctgctgg
      661 cacaacgtca tcttcatcca cagatcaact tttgccttac cgctttcgcc gccaccacca
      721 tttccggatt gcttttgcaa ctccccactt tcagcgatac acccaccatt gcgatggccg
      781 ccagcgttct gctgctggtg ccgggctttc cgttgattaa tgccgtcgcc gatatgttta
      841 aaggccacat caataccgga ctggcacgct gggcgatcgc cagtctgctg acgctggcta
      901 cctgcgtcgg cgtggtgatg gcactgacga tttgggggct acgcggatgg gtgtgatcga
      961 gtttctgttt gcattggcgc aggatatgat cctcgccgcc attccagcgg tcggctttgc
     1021 gatggtgttc aacgttcccg tgcgggcgtt acgctggtgt gcgctgcttg gcgcgattgg
     1081 ccatggttca cgaatgatct taatgaccag cgggctgaat attgagtggt caacttttat
     1141 ggcttctatg ctggtcggca ccattggtat tcaatggtcg cgctggtatc tggcgcatcc
     1201 gaaagtgttt accgtggcgg ccgttatccc tatgttcccg ggcatatcgg cttataccgc
     1261 aatgatttcg gcggtaaaaa tcagccagtt aggttacagc gaaccgttga tgattaccct
     1321 gttaaccaac tttcttacag cttcatcgat tgttggtgcg ttatccatcg gtctttccat
     1381 tcctggatta tggttgtacc gcaagcgccc tcgcgtataa aattgcctcg cttaagcaca
     1441 cggatgagag acagcctcct ctcctccgtg tgttactata aaagttatct cccttctcgt
     1501 tcatcgttcc atatttgaga aacagtatgt cttccagagt tttgaccccg gacgtcgttg
     1561 gtattgacgc cctggtacac gatcaccaaa ccgttctggc aaaagctgaa ggcggtgtgg
     1621 ttgccgtatt tgctaacaat gccccggcgt tttatgccgt cacgcctgca cgcctggctg
     1681 aactgctggc gctggaagaa aagctggcgc gtccgggaag cgatgtcgct ctggacgatc
     1741 aactctatca ggaaccgcaa gccgctcccg ttgctgtccc catggggaaa ttcgccatgt
     1801 atccggactg gcaacccgat gccgacttta tccgcctggc ggcgctatgg ggcgtggcgc
     1861 taagagagcc ggtgaccacc gaagaactgg cctcattcat tgcctactgg caggcggaag
     1921 gtaaagtctt tcaccatgtg cagtggcaac aaaaactggc gcgcagcctg caaatcggtc
     1981 gtgccagcaa cggcggactg ccgaaacgag atgtgaatac ggtcagcgaa cctgacagcc
     2041 aaattccacc aggattcaga gggtaacgat gaaaaacgtt ggcgacctga tgcaacgcct
     2101 gcaaaaaatg atgcctgccc atatcaaacc tgcattcaaa acgggtgaag agctactggc
     2161 ctggcagaaa gaacaagggg cgatccgctc cgccgctctc gaacgtgaaa atcgggcgat
     2221 gaaaatgcag cgcaccttta accgctccgg tattcgtcca ctgcatcaga actgctcctt
     2281 tgagaactat cgcgttgagt gtgaagggca gatgaatgcg ttaagcaaag cgcgccagta
     2341 tgtcgaagag tttgacggca acatcgccag cttcatcttt tctggtaagc caggaaccgg
     2401 caaaaaccat ctggcggcgg caatctgcaa cgagctgctg ctacgcggta aatccgtatt
     2461 gatcatcacc gtggccgata ttatgtcggc gatgaaagat accttcagga atagcggtac
     2521 cagcgaagaa caactgctta acgatctgag caacgttgat ctgctggtga tcgatgagat
     2581 cggcgtgcag accgaatcga aatacgaaaa agtgatcatc aaccagatcg tcgatcgccg
     2641 ctcttcttcc aaacgcccaa ccgggatgct gaccaacagt aatatggaag agatgaccaa
     2701 gttgctgggc gaacgcgtga tggaccgtat gcgcctgggt aacagtttgt gggtgatctt
     2761 caactgggat agctaccgta gccgtgtaac aggtaaagag tattaatccc cgtttctggc
     2821 ggtatactgc gacacaattc caccttgagt aatgatgatg aaaactgtta aacatcttct
     2881 gtgctgtgcc attgccgcca gcgcattaat ttccaccggg gtgcatgctg cgtcctggaa
     2941 agatgcgctc tccagcgccg ccagcgaact tggcaaccaa aacagcacga cacaggaagg
     3001 cggttggtcg ctcgcgtcat taactaactt gcttagcagc gggaaccagg ccttaagcgc
     3061 agataacatg aacaacgccg caggcattct gcaatactgc gcgaagcaaa agctggcttc
     3121 ggtaaccgat gccgaaaaca tcaagaacca ggtgctggaa aagctgggcc tgaacagtga
     3181 agagcaaaaa gaagacacca actatctgga tggcattcag ggtttgctga aaaccaaaga
     3241 tggtcagcaa ctcaatctgg ataacatcgg aacgactccg ctggcagaaa aggtgaaaac
     3301 caaagcctgc gatctggtgt taaagcaggg gctgaacttc atttcctgaa ccgcgaaacg
     3361 ccgcgtttta gctgttaccc ggctgacgcg gctctctcct gcccttttcc ctgctcctgg
     3421 acggttttac ccctgttaca cgggaagcga tcgcgatcaa aaaagtctgt ttataaacta
     3481 attcctaaca acatcgcatt tttttgacac tagaattgca gcaatatggc gacgccatta
     3541 cattgtgctt ctcaaaaagc ttaaacgttg gctaaacggc ccggtttagt gaggatcgcc
     3601 cgttgtcaga actactctct ttcgcccttt ttctcgcctc tgtgctgatt tacgcatgga
     3661 aagcgggacg taacacctgg tggtttgcag ccacattaac agtgctgggg ctatttgtcg
     3721 ttttaaatat caccctgttt gccagcgact attttactgg cgatggtatt aacgacgcgg
     3781 ttctctatac cttaaccaac agcctgaccg gtgctggcgt cagcaaatac atcctgccgg
     3841 gtatcggcat tgtgctgggg ctgacagcgg tgttcggtgc gctgggctgg atcctgcgcc
     3901 gtcgtcgcca tcatccgcac cattttggtt acagcctgct ggcgctctta ctggcgctgg
     3961 gttcggtgga cgccagcccg gcatttcgtc agataacgga actggtgaaa tcccagtcac
     4021 gcgatggcga cccggacttt gcggcttatt ataaagagcc gtcgaaaact atccctgacc
     4081 cgaaactcaa cctggtttat atctatggcg aaagtctcga gcgaacctat tttgataacg
     4141 aggctttccc ggatctcacg cctgaactgg gcgcgttgaa aaatgaaggc ctggatttca
     4201 gccacacgca gcagctgcca ggaacggatt acacgattgc gggcatggtg gcttctcagt
     4261 gcggcatacc gctgtttgcc ccctttgaag gcaacgcctc cgcctctgtc tccagcttct
     4321 tcccgcagaa catctgtctg ggcgatatcc tgaaaaactc gggttatcag aactatttcg
     4381 tgcagggcgc aaatctgcgt tttgccggta aagatgtgtt cctgaaatcg cacggcttcg
     4441 accacttata cggctcagaa gagctgaaaa gcgtggtagc cgacccgcac tatcgcaacg
     4501 actggggatt ctacgacgat accgttctcg atgaagcgtg gaaaaagttt gaagagcttt
     4561 cccgctcagg tcagcgattc tcactgttta ccctgacagt cgatacccat cacccggatg
     4621 gttttatttc tcgtacctgt aaccgcaaaa aatatgattt tgacggtaaa ccgaatcagt
     4681 cattcagcgc ggtaagttgc agccaggaga atatcgcgac gtttatcaac aaaatcaaag
     4741 cgtcaccgtg gtttaaagat actgtcatcg tcgtctcttc tgaccattta gcgatgaaca
     4801 acacggcgtg gaaatacctc aataagcagg atcgcaataa cctgtttttt gtcattcgtg
     4861 gcgacaagcc gcagcaagag acgctggcag tgaagcgtaa cacgatggat aacggcgcga
     4921 cggtgctgga cattctcggt ggcgataact atctcggact tggtcgtagc agtttatccg
     4981 ggcagtcgat gtcggaaatc ttcctcaata tcaaagagaa aacattgacg tggaagccag
     5041 atatcatccg cctgtggaaa ttccctaaag agatgaaaga gttcaccatc gaccagcaga
     5101 aaaacatgat tgccttctcg ggtagccatt tccgtttgcc gctgctgttg cgggtttcag
     5161 acaaacgcgt ggaaccgctg ccggaaagcg aatactcagc accgctgcgt ttccagctgg
     5221 ccgatttcgc tccacgcgac aatttcgtct gggttgaccg ttgctataag atggcacaac
     5281 tctgggctcc ggaactggca ctttccaccg actggtgtgt ctcgcagggg cagcttggcg
     5341 gtcagcaaat tgtccagcat gttgacaaaa caacatggaa gagcaagacg gcatttaaag
     5401 atacggtcat cgacatggcg cgttacaaag gcaatgtcga tacgctgaag attgttgata
     5461 acgatattcg ctacaaagcc gacagtttca tctttaacgt cgccggtgcg ccagaagagg
     5521 tgaaacagtt tagcgggatt tcccgtccgg agtcgtgggg ccgctggtcc aacgcgcagc
     5581 tgggcgatga agtaaaaatc gagtacaagc atccgctgcc gaagaaattt gacctggtga
     5641 ttaccgccaa agcatacggc aataacgcca gccgtcctat tccggtacgc gtaggcaatg
     5701 aagaacaaac tcttgtgctg ggcaatgaag tgaccaccac cacactgcat ttcgataacc
     5761 caaccgatgc cgacacactg gtaattgtgc cgccggaacc tgtctcaacc aacgaaggga
     5821 atatcctcgg acactcgccg cgtaagctcg ggatcggcat ggtggaaatt aaagttgtgg
     5881 aacgtgaagg gtaattcctg actgatgtgt aggtcgcata aggtgcgacc tacacacctt
     5941 ctccggccta caaaacatca ttgagaaaca gaaaaaaaac agcgcccaac acttccccgg
     6001 acgctgcatg gcaactttaa taatctcgcc ttatcagaaa gtaattacgc ctttaattaa
     6061 ctcacgattg ttaatcacat cgcgctcgta ggtttctgcc agcgtggcga acggatagcg
     6121 atgggttaac atcatgtcgg cagtgatttt cccttccgcc ataagtcgac cgactttagc
     6181 gaaatcttcc ggcgtggcgt tgcggctgcc catcatcgtc gtttcttttt tatggaattc
     6241 cggatcggag aactgcaact cacctttaaa caggccgaca aataccaccg tgccaccgtg
     6301 acgaatcaga ttcacggtgt tattcatcgc atgttgatta cctgtcgcgt cgatcacttt
     6361 ctgcgccagc gaaccaccaa actgcgcccg cagctgcgcg tcaaaatctt cggctgacgg
     6421 gtccagcacg ggcaactcca gacgcgttgc cacatgttca cggcgcgccg gactggtatc
     6481 cgccaccacc acctgtgcgc catcggcttt agcgattgcc gccgcgccca gaccgattgg
     6541 ccccgctccg accaccagca cctgctcgcc gggagcaatg gctgcgcgac gcaccgcatg
     6601 agcgctaata gcgaaaggtt caatcaatgc ggccgcctgc gggtcaatac cgtctgcggg
     6661 caaaatgttc gccaccggca cgctcaaata ctcactaaaa ccgccatcct gatgcacgcc
     6721 aatgactgaa attttttcac agcaattggt acgcccgctt ttacacgccg ggcattgctg
     6781 acaggcaaca taagggatca cagcaacttg ctgaccattt ttaagatcag caacattttt
     6841 acccagccca acaacctccc cacatatttc atggcctaaa acccgtggat aactaaaaaa
     6901 tggttgattt ccaccccagg catgaatatc ggtaccgcaa atcccgacag acttaatttt
     6961 tattaatgct tcattgtcac ccggaatagg aatctcgcgt tgtttccaga ctaattcttt
     7021 cggctgctgg caaattaaaa cattcatcgt agacatgatt cggctctcca ttttttgttg
     7081 ccttagatat caatgaaaat gaaaaatggc agcggaacgg aaaatctgtt ttgtgaaaac
     7141 acgcgcataa aaatgtttta aatcgggttt taatggactc acaaggagga aaatatgagt
     7201 cgttcacaaa atttacgcca caatgtgatt aaccaggtca ttgatgatat ggcgcggggt
     7261 catatccctt ccccacttcc atcgcaaagt gcgctggcgg aaatgtacaa catcagccgc
     7321 actacagtgc gtcatattct cagccactta cgcgaatgcg gcgtcttaac gcaggttgga
     7381 aacgactatg ttattgcgcg taaacctgac catgatgacg gtttcgcctg tactaccgct
     7441 tcaatgagtg aacaaaacaa agtgtttgag caggcttttt tcacgatgat aaaccagcgc
     7501 cagttacgcc caggggaaac tttttctgaa ctgcaactgg ctcgggccgc gggtgtcagc
     7561 ccggtggttg taagagaata tcttttaaaa ttcggccgtt ataatcttat tcaaagcgaa
     7621 aagcgcggcc agtggagcat gaagcaattc gatcaatcct acgccgagca gctgtttgag
     7681 ctacgcgaaa tgctcgaaac acattcactt cagcactttc tcaacctgcc tgatcatgat
     7741 ccccgctggc tgcaggcgaa aaccatgctc gaacgtcaca ggctactgcg tgacaacatc
     7801 ggcaatagct ttcgcatgtt ctcgcaactt gacagagatt ttcactcctt actgctttca
     7861 gctgccgaca atatcttttt tgaacaatcg cttgagatca tatcagtcat ctttcatttt
     7921 cactatcaat gggacgaaag cgatcttaaa cagcgcaata tcattgccgt cgatgagcat
     7981 atgaccattc tcagcgctct gatttgccgc agtgaccttg atgccaccct tgcgctccgt
     8041 aaccatttga attcagctaa acaatcaatg attcgatcca ttaatgagaa catgcgttat
     8101 gctcattaag tacggattaa aaacagcaaa ctattagcgg gtgcacggtt ttatcaaaag
     8161 ataaataccg gaaaattccc gcttacctat gctcacaatc agtcgactaa aaatgttttt
     8221 ttgtgagcgg tagtaaagtc ctaaaacttt aacctgccgt taatgtcaac cttgcgtaat
     8281 gcacaattac gtaaacaatt aaaattataa atacaggagt ccggcgtgga aaaagaaaat
     8341 atcaccctcg atccgcgttc ttcatttact ccatcttcgt cggcagatat tcccgtgcca
     8401 ccagatggat tagttcaacg cagtacccga attaaacgca ttcaaaccac cgccatgttg
     8461 ttattatttt ttgcggcggt aatcaattat ctcgaccgca gttcgctgtc ggtagcaaat
     8521 ttaacgattc gtgaagaatt gggattaagt gccaccgaaa tcggcgcttt gctctccgtg
     8581 ttttcactcg cttacgggat tgcgcaactt ccttgcggcc cactattgga tcgtaaaggc
     8641 ccgcgcctga tgttgggact ggggatgttc ttctggtcac tgttccaggc aatgtctggc
     8701 atggtgcaca gctttacgca gttcgtgttg gtgcgtatcg gtatgggaat tggtgaagcg
     8761 ccgatgaacc catgcggtgt aaaagtcatt aacgactggt tcaacatcaa agagcgcgga
     8821 cgcccgatgg gcttcttcaa cgcagcttct accattggcg ttgccgtaag cccaccgatt
     8881 ctggcggcga tgatgctggt gatgggctgg cgcgggatgt ttattaccat tggtgtactg
     8941 gggatttttc tcgccatcgg ctggtatatg ctctatcgca accgcgagca cgtagaactg
     9001 actgccgttg aacaagctta tctcaatgca ggtagcgtca atgcccgccg agatccgctc
     9061 agttttgccg aatggcgcag cttgttccgt aaccgcacaa tgtggggaat gatgctcgga
     9121 ttcagtggca tcaactacac tgcgtggctg tatctggcct ggcttcctgg ttacctgcaa
     9181 acagcctata acctggattt aaaaagcaca gggttgatgg cggctatccc tttcctgttt
     9241 ggggctgccg ggatgctggt caacggttac gttactgact ggctggtcaa agggggaatg
     9301 gctccgatta aaagccgtaa gatctgcatt attgccggga tgttctgttc tgccgccttt
     9361 acgctggtcg taccgcaagc gacaacatcc atgacagcgg ttctgctgat tggtatggca
     9421 ctgttctgta ttcactttgc cggaacatcc tgctggggct tgatccacgt cgcagttgct
     9481 tctcgcatga ctgcgtcggt gggcagtatc cagaactttg ccagcttcat ctgcgcctct
     9541 tttgcgccga tcattactgg ttttattgtt gataccaccc actcattccg tctggcacta
     9601 atcatctgcg gttgcgtcac cgcagcgggg gcactggcgt acatcttcct ggttcgtcag
     9661 ccgatcaacg acccacggaa agattaatct ccctatgccc gataacattt tgcttatcgg
     9721 gcatttttat ggcgattaaa acgtttccca gttctcaccg ctatctgcca cggccatttt
     9781 acgcggcgca gctggcatca cggtttttac cacagccgat gtttcacgct gctgttgctg
     9841 ctgttgctga atccggaaca ctgccactgc ttcggtcagg cgactggcct gctcttccag
     9901 cgcggcggcg gcggcggcag attcttccac cagcgcggcg ttctgttgag ttacccggtc
     9961 catctcagca accgctaagc caacctgatc gataccacgg ctctgctcat cagaagcaga
    10021 agcaatttcg cccataatgt ccgtcacgcg ggtcacagca ctgacaatct ccgccattgt
    10081 ttccccggcg ctttcgacca gcgtagagcc aacatccact ttccccaccg agtcttcaat
    10141 caggctttta atttcacgag ccgcctgggc gctacgctgg gccagattac gcacttctcc
    10201 cgcaaccacc gcaaaaccac gtccttgctc acccgcacgc gctgcttcaa ccgccgcgtt
    10261 caaagccaga atattggtct ggaaggcaat gccgtcaatt acgctgataa tatcggcgat
    10321 tttctgcgaa ctggtggaga tatcacgcat agtctgcacc acgttatcta ccactttgcc
    10381 gccgcgttgc gccgtttcag aagcacttaa cgccaggtgg ctggcctggc gcgcattctc
    10441 ggcgttctgt ttcaccgttg cggtcagttg ctccatgctg gctgccgtct cttccagcga
    10501 agcagcctgt tgctcggtgc gcgaagagag atcgttattg ccggtagcga tttcgctggc
    10561 accgctatag atggcattgg ccccgttgcg cacatcaccg acggtacgca tcagctctcc
    10621 ctgcatatgg cgcaaactct ctgccagttg ccccatctca ttagagccat ccacctcaat
    10681 cggtttcacc agatcgccgc ctgcaatatg acgaatgctg tcaatcaggc gattcattgg
    10741 cgctaccagc gaggctttaa taccgaacca gacggcgaag atgaccgcca gtacgacgat
    10801 catcacgccc accagaatcc acatcgcctg gctgtaggag gcattgttat cgctgacggc
    10861 gatatcatgg agccgatcgt tttgttccat gtaagccaca tactgcttct cgaaaccgtc
    10921 ctgatatccc tgagtcggct gatcaaagaa ctcgttgatt ttgcctgcac ctaacagttg
    10981 gatcagctcc gccagcgcat tgtgataaat atcgtaatta cgtttgatct ctgccgctgc
    11041 ggcggtgctc tgacgcgggt cacgcggcaa cgcttcgtaa tccgcccagt ttttttccgc
    11101 ctgtttcagc gaaatactgg cactctgcat cagctcagca acggttgaac cgctaccaat
    11161 attattctga tccatcatgt agcggatacc cgcgcggttg agggtgttac gcgtctgcaa
    11221 caacgcgacc cagctgccat tcagcgtgga ttgctgctgg cgaatggttt gtaaaacagt
    11281 gaaattttct ttgtcattct ttaaggcatt aaagaacaga ccgcctgatg tcagttgtaa
    11341 aaggccaaaa acggccaaaa ccagcagtaa gctggtcaca attttgatac gttttaacat
    11401 ggtttctctt tcctgtggac cgatgcaaga ttttcggcct ggaaaggaaa aactttatga
    11461 atatcccgcg gagattacgc cgagtaattt tattcacact ctgaatttaa aaagccatta
    11521 tttacataaa ttattcacaa tataaatatg tgatatgaat cacatattta tcgtcactta
    11581 aacgacgcct ttgccgctca accgcaaaac tgaccgctta catccctaaa ataaccactc
    11641 agttatttac cttactttac gcgcgcgtaa ctctggcaac atcactacag gatagcggtc
    11701 aatttacctc ctcaaacgca acgcaaacct agaacggctt cggccaacta ttaatcaata
    11761 catgccaggt tttactatgg atactaaaaa gatattcaag cacataccct gggtgattct
    11821 cggaatcatc ggtgcattct gcctcgcggt agttgcatta cgtcgggggg agcacgtcag
    11881 cgccctgtgg atcgtggtcg cctctgtatc ggtgtatctg gtggcgtatc gctactacag
    11941 tctgtacatc gcccagaagg tgatgaaact cgaccccacg cgcgcgacgc ctgcggttat
    12001 taacaacgac ggtctgaact acgttccgac caaccgttac gtgttgtttg gtcaccactt
    12061 cgccgctatc gccggtgctg gtccgctggt gggtccggtt ctcgccgcgc agatgggcta
    12121 cctgcctggc acgctgtggc tgctggcggg ggtcgtgctg gccggtgcgg ttcaggactt
    12181 tatggtgctg tttatctcct ctcgccgtaa tggcgcatct cttggtgaga tgatcaaaga
    12241 agagatggga ccagtaccgg ggactatcgc gctgtttggc tgtttcttaa tcatgatcat
    12301 catcctcgcc gtcctggcgc tgattgtggt taaagccctg gccgaaagtc cgtggggtgt
    12361 cttcaccgtt tgctcaaccg taccgattgc gctgtttatg ggtatctaca tgcgctttat
    12421 tcgtccgggg cgtgtgggtg aagtctctgt cattggtatc gtgctgctgg ttgcctctat
    12481 ctacttcggt ggcgtgattg ctcacgatcc gtactggggt ccggcactga cctttaaaga
    12541 caccaccatt accttcgcgc tgattggcta tgcgtttgtt tccgcactgc tgccggtgtg
    12601 gctgatcctc gcaccgcgcg actatctggc aaccttcctg aaaatcggcg ttatcgtcgg
    12661 cctggcgctg ggtatcgtgg tgctgaaccc ggaactgaaa atgcctgcca tgacccagta
    12721 cattgacggt actggcccgc tgtggaaagg cgctctgttc ccgttcctgt tcatcaccat
    12781 cgcctgtggt gcggtatctg gcttccacgc gctgatctct tccggtacga cgccaaaact
    12841 gctggctaat gaaaccgacg cgcgtttcat cggctacggc gcaatgctga tggagtcctt
    12901 cgtggcgatt atggcgctgg ttgctgcgtc catcatcgaa ccgggtcttt acttcgcgat
    12961 gaacaccccg cctgctggcc ttggcatcac catgcctaac ctgcatgaaa tgggtggcga
    13021 gaacgcgccg atcatcatgg cgcagctgaa agacgttacc gcacacgcgg cagcgaccgt
    13081 cagctcctgg ggcttcgtga tttcgccaga gcagatcctg caaaccgcga aagacattgg
    13141 tgagccttct gtcctgaacc gtgcaggtgg tgcgccgacg ctggcggtag gtatcgctca
    13201 cgtgttccac aaagtgctgc cgatggctga catgggcttc tggtatcact tcggtattct
    13261 gttcgaagca ctgttcatcc tgaccgcgct ggatgcgggt acccgttctg gccgctttat
    13321 gctgcaagac ctgctgggta acttcatccc gttcctgaaa aaaaccgact ctctggttgc
    13381 cggtatcatc ggtactgcgg gctgtgtggg tctgtggggc tacctgctgt atcagggcgt
    13441 ggtcgatccg ctgggcggcg ttaagagcct gtggccgctg ttcggtattt ccaaccagat
    13501 gctggcagcc gtagcgctgg tactgggcac cgttgtgctg attaagatga agcgcaccca
    13561 atacatctgg gtaactgttg ttccggctgt atggctgctt atctgcacca cctgggcgct
    13621 gggcctgaaa ctgttcagca ccaacccgca gatggaaggc ttcttctaca tggcaagcca
    13681 gtacaaagag aagattgcta acggtactga cctgacggcg cagcagattg ccaacatgaa
    13741 ccacatcgtt gtgaacaact acaccaacgc gggcctgagt attctgttcc tgattgtggt
    13801 gtacagcatc atcttctacg gtttcaaaac gtggcttgcg gtgcgtaaca gcgacaaacg
    13861 tactgacaaa gaaacaccgt acgttccaat cccggaaggc ggcgtgaaga tctcttcgca
    13921 ccactaaccg tgtttagccc cgcttcggcg gggctttgtt cttatcagag tgaactatgt
    13981 ttggtaactt aggacaggca aaaaaatatc tcggccaggc ggcgaagatg ttgattggca
    14041 ttccagacta cgacaactac gtcgagcata tgaagaccaa ccatcccgac aagccgtaca
    14101 tgagctatga agaattcttc cgcgaacgcc agaatgcgcg ctacggcggc gatggtaaag
    14161 gcggtatgcg ctgttgttaa tggagagagc atgaacccga ttgcagttac cctactcacc
    14221 ggttttttag gcgcaggcaa aaccaccctg ctgcgccata ttcttaacga acaacacggc
    14281 tacaagattg ccgtgattga aaacgaattc ggcgaagtct ccgttgatga tcaactgatt
    14341 ggcgaccgcg ccacgcagat caaaacgctg accaacggct gcatctgctg ttcgcgctcc
    14401 aacgagctgg aagacgcact actcgacctg ctggataatc tcgacaaggg caatattcag
    14461 ttcgaccgtc tggtcattga atgcaccggc atggccgatc ccggcccgat tattcagacc
    14521 tttttctccc atgagatttt atgccagcgt tacctgctgg acggcgtgat tgcgctggtg
    14581 gatgcggtac atgccgatga gcagatgaac cagttcacca tcgcccagtc acaagtgggc
    14641 tacgccgacc gtattctgct gactaaaacc gacgtcgcag gcgaagcaga aaaactgcgt
    14701 gaacgcctgg cgcgcatcaa cgcccgtgca ccggtctaca ccgtcaccca cggcgacatc
    14761 gacctgggcc tgctgttcaa caccaacggt tttatgctgg aagagaacgt catcagcacc
    14821 aaaccgcgtt tccactttat cgcggataaa caaaacgata tttcgtcgat tgtggtggaa
    14881 ctggattacc cggtagatat cagcgaagtt tcccgggtga tggaaaacct gctgctggaa
    14941 tcggcggata aactgctgcg ttacaaaggg atgctgtgga ttgacggcga acctaaccgc
    15001 ctgctgttcc agggcgtcca gcgcctctac agcgccgact gggaccgccc gtggggcgat
    15061 gaaaaaccgc atagcacgat ggtgtttatc gggattcagt tgccggagga agagattcgg
    15121 gcggcgtttg cggggttgag gaagtaatta tggatgatgg ccgccatgtg gcggcctgaa
    15181 ttattttttg ttctgatcgc gcagcatcgc ttcacgtaaa attgcgttca ggcgagtttg
    15241 atagccttta ccaggtcgct tcagccattc catcacatca gcatcaatac gcaccgaagc
    15301 ctgggttttc aatggccgat aaaacttacc gcgttctgcg ttagaccatt gctcatcgct
    15361 ggaaggcggg atatcactgt aatcaatatc ttcgtcgaat ttattcgcca gtgccttcag
    15421 ttcggcctca tgctgcacat cgagtgtaga gggtgtccct cgtttatgtt taaccatgct
    15481 catagcggct cctctcttta cgatctgctt ttcgtgcact gatgattcga ataatttcat
    15541 ttccgctttc gaaacggatg gtatgcgcaa ccagaataac cacgataccg tgaaccaggc
    15601 cgatagtctg ccagcgatac tcaccgtttt ctatgcgatc ttgctgtgac aaatgttgtg
    15661 gatcatcaaa cactaacacc gcatcttcaa agcggatgcc atgtttcacc cgattacttt
    15721 tggccttgtt tgcatcccat tcaaactcca ttggcatagt tgccatccct aattgtatat
    15781 acaaaaatgt atctacaatt attctgcaat tatagcgttg atgttggaaa tagcatcacg
    15841 ttttggataa tcaaccatga aattgacaat gagtaagttg gacttgattc atccaataga
    15901 atttctcgcc tgacatggca cactaaacac ctcgctgtcg ttaagggatt accgtgaaaa
    15961 actataaagt tattaccccg ctttttccta cctatgcaca ggttaaagct atgatgaaag
    16021 ccgtctcagg ctattccctg aaagcggtac gcaatatgat taccgccatt cgcgatcaaa
    16081 ccggtacgcc gcaaaaaccc gttgactggt cggaacctga cctgtggatc agcgaacgct
    16141 taacgggcga agatgccgac atcgcccgtc gtatttggga tacagataat cacatattga
    16201 acccgcgcca cagctacggc tgctacttat tcctcaacta tccccagttt gagctgatgg
    16261 aaagcacgcc agatgatacc tggcagccca cctcgcgcgg gcaaaaattc ctgcaagatg
    16321 acgaaaaaac gctgcgttca ctggatgacc aggaaggcat tctgcaactg cttgagctgc
    16381 tggctggccg agaaatgtcg cgccgcgccg atttattgcc ggaatggcag gcctttttgc
    16441 atcagcattc gaaattcgcg tctgcaagtt cagtgaaaag cacgctctac tcccgtctct
    16501 ataaccttat tgaccgtggc atggttactc gcgaaggtat gagctattgc atcaccgata
    16561 ccggacgcgc ctggcttgga aaagcgttgc cagcacgaaa aagcgatccg cgtaaagagc
    16621 tgctggaagc ggtgaaacgc tacaacgagc agcaaaaaga gctgctgcgc gaacaaatca
    16681 gcacaatgaa cccgtacaaa tttgaacaac tggtcggtca attactggaa gcaatgggct
    16741 acgagcaggt cgaagtgacc aaagcctcag gcgataaagg tgtggacgtg attggtcagg
    16801 tgcaggtcgg catcaccact attaccgaag tggtgcaggt caaaagaatg cagaacacca
    16861 tcactcgacc gtatatcgac cagttgcgcg gagcgttgcc ttaccacaag gccattcgcg
    16921 gtacgctcat caccaccggg aaatttgcag cgaaatgtgc agaagcggcg ctctttccgg
    16981 gggccgcgcc cattacgctt atcgacggcg atcgcttact ggaactgtta atcgaaaata
    17041 acgtcggcat tcgccgcagc aatgcagtgg aattgctgga tgtggatttg cagttgtttg
    17101 atgagctgga gatggattaa agggcgaaat ccgccgcctc aaccattaca atagcgaccc
    17161 aatttatctg aacagagttc atcatggcca aagcaccaac taaaaaagcc aaagcaaaaa
    17221 aaggctttga agaaacatta tgggataccg caaaccaact tcgcggtagc gttgagtcct
    17281 ccgaatacaa gcacgtggtg ttaagcctcg tgttcctgaa attcatcagc gataagtttg
    17341 aagcacgccg caaaaaaatg attgccgatg ggcaagctga cttccttgag atggaagtgt
    17401 tctaccagca ggacaacatt ttctacctgc cggaagaggc gcgctggtcg tttatcaaac
    17461 aaaatgccaa acaggacgat attgcggttc gtattgacac cgccctctcg acaattgaga
    17521 aacgtaaccc aaccctgaaa ggcgcgctgc cagacaacta cttcagccgt cagaatctgg
    17581 aaaccaaaaa actggcgtca ctgattgata ccatcgacaa catcgaaacg ctggcacacg
    17641 aaactgacgt tgaaacgttg tcgaaagaag acctggtcgg acgcgtttac gaatacttcc
    17701 tcggtaagtt tgccgcaacc gaaggcaaag gcggtggaga gttctacacg cccaaatgtg
    17761 tggtcacgct gttaactgaa atgctcgaac ccttccaggg caaaatttat gacccgtgct
    17821 gcggctcggc agggatgttc gtgcagtcgg tgaagttcgt cgagagccat cagggtaaaa
    17881 gccgtgatat cgcgctgtat ggtcaggaac tgacagccac gacgtataaa ctggcaaaaa
    17941 tgaacctcgc cattcgcggt ctttcagcta acctcggcga acgcccggca aacactttct
    18001 ttagcgacca gcacccggac ctgaaagccg actacattct ggcgaacccg ccgttcaacc
    18061 tgaaagactg gcgcaatgaa gccgaattaa ccgaagatcc acgctttgcc ggttatcgta
    18121 tgccgccaac cggtaacgcc aactacggct ggattttgca tatgctctcc aagctgtcgg
    18181 ctaacggcac agcaggtttt gtgctggcaa acggttcgat gagttctaac accagcggtg
    18241 aaggcgagat ccgtgcacag atgatcgaaa atgatctgat tgactgcatg atcgccctac
    18301 ctggacagtt gttctacacc acgcagatcc cggtgtgttt atggtttatg accaaatcga
    18361 aggctgccga cccggccaaa ggttatcgtg atcgtcaggg cgagacgctg tttattgatg
    18421 cgcgtaacct cggcaccatg attagccgca caactaaaga gttaacggcg gaagatattg
    18481 ccacaatcgc cgatacctac catgcctggc gcagcacgcc ggaagaactg gctgcacgga
    18541 ttgcgcgtgg tgacagcaag ctggaaaaat atgaagacca ggcaggcttc tgcaaagttg
    18601 cgaccctgca agatattaaa gataacgact acgttctgac accgggccgc tatgtgggtg
    18661 cagccgagca ggaagaagac ggcgtggcat ttgagaccaa aatgcgtgaa ttgtcgaaga
    18721 cgttgtttga gcagatgaag caggcggaag aactggatcg tgcgattcgc cagaatctgg
    18781 aggcgctggg ttatggggag taagtggtgt atatatcgct taggtgatat agctgaattt
    18841 tcatacggaa aaatgcctaa aaaggagttt gttggtacag gtgactatgt cattttttca
    18901 ggatataaat acacagaaag ctaccctgaa aaaaatactt cggcaggtga gttaattgtt
    18961 gttgcccgag gtgttggtgg aactggcg
//
LOCUS       DAFGPF010000092        18704 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFGPF010000092 DAFGPF010000000
VERSION     DAFGPF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18704
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.092"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(39..947)
                     /gene="galU"
                     /locus_tag="LSX49_003650"
     CDS             complement(39..947)
                     /gene="galU"
                     /locus_tag="LSX49_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL7170011.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIKK"
     gene            complement(1149..2162)
                     /gene="rssB"
                     /locus_tag="LSX49_003651"
     CDS             complement(1149..2162)
                     /gene="rssB"
                     /locus_tag="LSX49_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HBL7170012.1"
                     /translation="MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISQCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            complement(2254..3159)
                     /gene="rssA"
                     /locus_tag="LSX49_003652"
     CDS             complement(2254..3159)
                     /gene="rssA"
                     /locus_tag="LSX49_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HBL7170013.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVEKKMDELLPLVRTNI"
     gene            3272..3730
                     /locus_tag="LSX49_003653"
     CDS             3272..3730
                     /locus_tag="LSX49_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HBL7170014.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQ
                     DADYLIKTWHPSCGAAALRAELIAGFAHTEWLGLTVFEHCWQDGGDIGFVSFVARFTE
                     GGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            3780..4622
                     /gene="purU"
                     /locus_tag="LSX49_003654"
     CDS             3780..4622
                     /gene="purU"
                     /locus_tag="LSX49_003654"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HBL7170015.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDNLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            4782..4866
                     /locus_tag="LSX49_003655"
     tRNA            4782..4866
                     /locus_tag="LSX49_003655"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4816..4818,aa:Tyr,seq:gta)
     gene            complement(4883..5974)
                     /locus_tag="LSX49_003656"
     CDS             complement(4883..5974)
                     /locus_tag="LSX49_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA desaturase"
                     /protein_id="HBL7170016.1"
                     /translation="MNLFNPDRLITFPADDPQLVKQLQSGTKVYLAKSGDHRYADGWA
                     FVKMAVLIIACFSCYLLALFQRQWGLYLLWYLAMMFCAMLLAVNVVHDASHDAFLRGK
                     KTNARLNRWVAFPMGLDPDCWRVRHVRFHHGFTNIEFYDPDTAENGILRQTPWQRWRP
                     FMRQQHRYWPLVAALTFPWYIWVVDWLDRAGFTPVTRHLALRGFAGWGYFLAGKLAHC
                     ALCLIIPWLLSDFSFMTILLTYLLSQLLASLIFVTLIIGTHWAKGHTQLPPEEGKMPV
                     GRLAHTFATTFDWTPQPAWLGYWLGGINLHLTHHLFPHWHHRHYSALSRIIAQIASQQ
                     GLDYQLLTLADLLRLQQQFLRRMGEKPKV"
     gene            complement(5961..7085)
                     /locus_tag="LSX49_003657"
     CDS             complement(5961..7085)
                     /locus_tag="LSX49_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterol desaturase family protein"
                     /protein_id="HBL7170017.1"
                     /translation="MSDLLFPIISMVLLVLAEAGVLQFTGRQKVDWLDVIFNINSGHM
                     MLWLFRCLEVLCYGLVVNHFSLGLFDNVPVILLWLFTILAWDFGFYWLHRWHHEMRPL
                     WAVHVVHHQGEHYNLSLGVRNSWYSSLTSIPFFMLLAMLGVPLQVFLAVSIIHYSWQF
                     FNHNALTPKLGWLEKVLITPSHHRVHHLNQKQYADTNYGGTFLLWDKLFGSYSAGPEY
                     DVGYGVKNSRLSCNPMRESNLPFLRLMGFCSFGKAIEGRYQSSPWAVGAGVILLFMLV
                     LGYIQQYGYGIEFITSEQAVLFVLLAAGSVALGGMSDGQHWGMILWCSVTLSLLYFIV
                     YMCSWSTLLWKGLVGILLAHCLLFVIGVGRKSLRKQYEPV"
     gene            complement(7078..7680)
                     /locus_tag="LSX49_003658"
     CDS             complement(7078..7680)
                     /locus_tag="LSX49_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002432219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol phosphorylceramide synthase"
                     /protein_id="HBL7170018.1"
                     /translation="MSNSLLRLKQMLLGWGTVGVIYNFSDYLQGEGYQLTPSIIDNLI
                     AFSPSAVWLYLSFFFIVPLGYLSTPLCHLRWLARSMQISALVAGVFYLLWPTTMHYPS
                     FDQMGISAGALNRLIAIDSSQNCFPSLHAALTLLAVWAIAKKGNRWLTLMSVVWAIAI
                     AFSILQLRRHLFIDLVGGALLASICGWICATCEKRKTQYE"
     gene            complement(7677..8963)
                     /locus_tag="LSX49_003659"
     CDS             complement(7677..8963)
                     /locus_tag="LSX49_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoF synthetase"
                     /protein_id="HBL7170019.1"
                     /translation="MIPLMLIWRYFRTRRLHFTDREALENWQAKRLHQFRQNVLSHSP
                     WFQRYLTLPFNQWPMMDKALMMTHFDEMNTAGLKRDELLDCAMRSEQSRDFKPCVGKF
                     SVGLSSGTSGRRGLFVVSPHEQQMWAAGVLAKVLPDDLFAKERVALFLRADNNLYQSV
                     NNRWLSLDFYDLLAPFQAQLKLLQQRAPTIIVAPAQVLRALALEVMAGELTLKVKKVI
                     SVAEVLEPQDRELLRNVFHNVGEIYQATEGFLASTCRCGTLHLNEEFVHIEPQWLDEH
                     RFVPIVTDFTRTTQPIVRYRLDDVLVASEQPCPCGSATMAIARIEGRQDDQLQLPTRS
                     GDIQTVFADACSRVLAMTLPLTVDYRLLQTGSAQLTLIADCELWMLEHCREALNALFI
                     RQDIAVGQLIWSLELQTVPVSFTAKRRRIVRQWGRE"
     gene            complement(8960..9766)
                     /locus_tag="LSX49_003660"
     CDS             complement(8960..9766)
                     /locus_tag="LSX49_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL7170020.1"
                     /translation="MAKITAFETGWCTHISCIALKGAGLKVCKFPARAWLLEVGDKRW
                     LWDTGYSSWFEHYTQSGVFRLYRQVTPVYFDPQQALVRQLSATGLAAKDVDAIILSHF
                     HADHIAGLRDFPDVSCICSGEGWRQVRTLRGVTALRQAFVPGLIPENFDSSLRFIESF
                     ASVNLPAQLAPFECGYLLPESNGEIILVPLPGHAAGHIGAFVLTDNGWTLLAGDAAWA
                     PANYRELRGPSPLAHLVMSDSHAYYHTLGQLHQLWQNGVVEIRLCHEGDL"
     gene            complement(9744..10760)
                     /locus_tag="LSX49_003661"
     CDS             complement(9744..10760)
                     /locus_tag="LSX49_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL7170021.1"
                     /translation="MKILVTGATSGLGRNAVQYLLQSGESVVATGRNCEVGRSLTNAG
                     AQFVALDLTEATEDDCARLMDGCDAVWHCAAKSSPWGDKTAFWLANVKVTHTLAQAAG
                     RLNIPRFIHISTPAVYFDFQHHYDLPETYLARAFSSHYASSKYAAEQVIAGAVSRYSA
                     TRFILLRPRGLFGPHDQVIVPRLMQQLQQGGGCLRLPRGGDALLDLTFVQNVVYAMRL
                     ATNVEGLRSGSIYNISNHQPQQLSVMLDALLHQQLGLSYRIAAVPWSLLSLIARGLEL
                     YGKCVNQEPVITRYSAGTLCFDMTLSAQKAITELGYRPRFSMEQGIAITGQWLREHGK
                     NNRI"
     gene            complement(10757..11764)
                     /locus_tag="LSX49_003662"
     CDS             complement(10757..11764)
                     /locus_tag="LSX49_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001385314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBL7170022.1"
                     /translation="MARPNQPTISAALKIIATGIALPPDQITSKQLDVQLNKPVGYVE
                     RRSGICWRYFARNDASQAELAAEALHNALVAAALNPSDIDLLICASAIAVQALPCSAI
                     HILKAAAMPVGVAGFDINSSCVSFISALEVAAGLLNCGAYRRIAIVSADIASRGIDWD
                     HEESSLIFGDGAACAIVERGDGRSGIIASLIEMYPEGSELCEIRAGGTRRNPRSGVSD
                     SDFLFHMQGKPLFRFASSLIEDYFSRLLQKSSLQLSDIGTVVPHQASHLSLEHMRKRL
                     RVPESALIDVYRFYGNQVAASIPTALHEAVISGRFTADKPVMLIGTAAGLTLAGMVLL
                     P"
     gene            complement(11892..12569)
                     /gene="narI"
                     /locus_tag="LSX49_003663"
     CDS             complement(11892..12569)
                     /gene="narI"
                     /locus_tag="LSX49_003663"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HBL7170023.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(12569..13279)
                     /gene="narJ"
                     /locus_tag="LSX49_003664"
     CDS             complement(12569..13279)
                     /gene="narJ"
                     /locus_tag="LSX49_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HBL7170024.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLPKEDAHALG
                     IFLRDLTTMDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLAQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVLFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(13276..14814)
                     /gene="narH"
                     /locus_tag="LSX49_003665"
     CDS             complement(13276..14814)
                     /gene="narH"
                     /locus_tag="LSX49_003665"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HBL7170025.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTICSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            complement(14811..18554)
                     /locus_tag="LSX49_003666"
     CDS             complement(14811..18554)
                     /locus_tag="LSX49_003666"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HBL7170026.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAREAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVMGQKSNGNPEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKELGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
BASE COUNT         4656 a         5099 c         4586 g         4363 t
ORIGIN      
        1 tgctcaacac cgtttcgtgg aaaacaccga tacggatgtt acttcttaat gcccatctct
       61 tcttcaagcc aggctttaaa ttccgtgcca agggtgttat gacgaatacc gtattcaacg
      121 aaggcctgca tgtaacctaa tttattaccg cagtcatggc tcttcccttt catatgatag
      181 gcttcaaccg tttctttttc gatcagcata tcaattgcgt cggtgagctg aatttcatca
      241 ccagctccag gaggggtttt tgccagcaac ggccaaatat ccgcgctaag tacgtaacga
      301 cccacaatag cgagattaga cggcgcaaca tccgcttttg gtttttcaac cacgccaacc
      361 atcggtacgc tttcacccgg cgctaattca acgcctttgc aatccacaac gccatatgcg
      421 gtcacatcag caaccggttc aaccatgatc tggctatgac ccgtttcatc aaagcggcgg
      481 atcatctctg ccaggttatc ctgtgataaa tcggattcat attcatccag aataacgtca
      541 ggcaaaataa cagccacagg ttcatcaccc actaccgggt gagcacacaa taccgcgtgt
      601 cccaggcctt tcgccagccc ctgacgaact tgcataatag tcacgtgcgg cggacaaata
      661 gactgcactt catcaagcag ttgacgtttt acacgttttt ccagcattgc ttccagttca
      721 aaactggtat caaagtggtt ttcaatagag tttttagatg agtgagtaac cagcacaatt
      781 tcagtaatgc cagccgcaat acattcattc acgacgtatt gaattaatgg cttatcgaca
      841 agtggcagca tctctttcgg gatggctttc gtcgccggca acatcctggt tcctaatccc
      901 gctacgggga taacggcttt tttgactttc gtattaatgg cagccattta aattctcctg
      961 gactgttcgt gttttgaacg tgttcatatt tctgtatcgc atcccagtat atcagcaccc
     1021 cgaaggggct aagttctgaa aaggaggcga gttagcataa ttaagacaat tacttatacg
     1081 aatagcgacg atagtaccac cagccgacat tagcaggtaa tgcaaattta gcccgtgtta
     1141 tcgtttgctc attctgcaga caacatcaag cgcagccgac caccggttcc ccatatttgg
     1201 cattgccagg catcgcatcg ctggctcaat tgattcaaat aagcgttacc taaagtgcct
     1261 aacggaacac cattactgat ttgcacctga tgttcgccgg tatttaacgt cgcattcaga
     1321 cccgcagaaa ccagaatgag atttttcagt tcgcgatgat aatagccaac taatagcgga
     1381 aactgccccg gcagattggc ctgacggagt aaatggttta cctgcttcaa taacgcgccc
     1441 aactctggca accgttgatt ttggtgtgca agctgttcct gtaataatcc gttaaacaat
     1501 gcgcgtaata acaaggcagc aagtacgcca ttatgtccag ctcgggtgac atcaaggcaa
     1561 taaaatgcca gatcgttttc cgaaagtgcg gcaatatcaa gcaccaggcc gggtttgtcc
     1621 gcggcaacta attgacgata attaacccgg cattgggaaa tcacctgctg aaccggcggt
     1681 tgtagttcct gtaataattt cgccgctgca gcagggttat caaccattgc atcccagtcg
     1741 cgaaaaagcc tttcctcttc ctcaacgcgg gaattaaaca tgctgggata gagacaggca
     1801 aaaaccatct cgcgcaagcg attcagatct ttaaccggtt tcagcaaaac atcttcaacg
     1861 cccagacgta acgctttggc aatatctgcc atattttcag tggcagatat caccagaact
     1921 ggtgtctggt cacctctgtt gcgtatatgt tccagcagtt taagcccgtt cattcgtggc
     1981 atcgcgatat cacatatcat caggtctgga gtgaaacctc ccagcaactc aagggcatcc
     2041 accccatcag ccgccagtac cgttgtcgct cccaatgagg aaaaccacga atccagaagc
     2101 gagcgaaata cctgctcatc ttcaacaatg agaatctgtt ttccgaccaa tggctgcgtc
     2161 atgttctctc ccctgactgg ctttactcaa tagtggcatg ctattgccac ctacgcctgt
     2221 cagaattaac ttaagtgtag ataaaaattc tggtcaaatg ttggtgcgta ccaacggcaa
     2281 aagttcgtcc attttctttt ccactgccag ctgtccggcc gcaatggcag cgtgcgcgcg
     2341 atggaaatca agcgtagata tttgcgggca aacaggttga atcagaatat cgggcggatc
     2401 acctgccatg cggttccttt taaggcggtt ctccagcacc tggatagaag tggtcataat
     2461 ctctgttgcc gttggcgctg tcaccgcccg acgtgtcgtt atgctgccta acctttcttt
     2521 cagacgcgca tgccacggca gagaatcacc attctcgcta ttttcttcac tgacattaaa
     2581 ggagagcaaa tcttgttgca tcaaatgagc atcgtgctgc aggtcgaccg ctatcacaat
     2641 atcagccccc aatgcacgcg tgagggaaat aggaattggg ttaactacag cgccatcaac
     2701 cagccagtag ccgttatgcg caacgggtgc cattagtcct ggaatactgc atgatgcacg
     2761 aatagcaaga tggagatcgc cttcagtaaa ccataattca cgcccagtac ttaaattggt
     2821 ggcaacagcc gcgaagcgac gggaacaatt ttcgatctct gtttccggca ttatttcgcg
     2881 atattgattg aagacacgct cgccgcgcag taacccaccg cgctgccagg agagatccat
     2941 caggcgtaaa acatcccaat aactgaaaga ggtcacccaa tcttccagcg cagataatcg
     3001 atcgcatgca taggcagcgc ccaccagcga accaattgaa catcctgcaa cgatatcaat
     3061 ttcaataccc acttttttta gcgcattaat tacgccaata tgcgaccaac ctcttgccgc
     3121 gccagatccc agcgccagcc ctatttttat ctttctcatt attcccgcaa gattcccctg
     3181 gaatgcaatc gtagccacat cgctactgct cggttaacat agtgctactc aggcggttaa
     3241 tacgccgtta ttgtttccag ggagattatt tgtgtctcag ctttgtccct gtggtagtgc
     3301 tgtcgagtat agcctatgtt gccaccctta tgtgtctggt gaaaaggttg cacctgatcc
     3361 agaacatctc atgcgttcgc gttactgcgc ttttgtgatg caagacgcag attatttaat
     3421 aaagacctgg catccatctt gtggagcagc ggcgttacgt gccgaattga ttgccggatt
     3481 tgcgcatact gaatggttgg gattgaccgt atttgaacat tgctggcagg acggcggcga
     3541 tatcggattt gtcagttttg ttgctcgatt taccgagggt ggcaaaacag gtgcaataat
     3601 tgaacgttcg cgatttttga aagaaaacgg tcaatggtac tatattgacg gtacacgtcc
     3661 gcagtttggc cgcaacgatc cctgcccttg tggttcaggt aaaaaattta aaaagtgctg
     3721 cggccaataa tggttgacgg tacggtttag caaacactct caacaaggtt tttccagcaa
     3781 tgcattcact ccaacgtaaa gttctgcgta ctatttgtcc ggaccaaaaa ggtctgatcg
     3841 cacgtattac caatatttgc tacaagcacg agttaaatat cgtgcagaac aatgaatttg
     3901 tagatcatcg taccgggcgc ttttttatgc gcacggaact ggaagggatt tttaatgatt
     3961 ccaccctgct ggcagatctc gatagcgcat tgccagaagg ctccgtgcgt gagctgaatc
     4021 ctgccggtcg tcgccggata gtgattctgg tcactaaaga agcacattgc cttggcgatt
     4081 tgctgatgaa agccaattac ggcggcctgg atgtcgaaat cgcggcagtt attggtaacc
     4141 acgataattt acgttctctg gttgagcgtt ttgatattcc gtttgagctg gtaagccatg
     4201 aagggttaag ccgcaacgag cacgatcaaa agatggcgga tgccattgat gcttatcaac
     4261 ctgactatgt ggtgctggcg aagtatatgc gggtattaac gccggaattt gtggctcgct
     4321 tcccgaataa gatcatcaat attcaccatt ccttcctgcc agcgtttatc ggcgcacgtc
     4381 cttatcacca ggcctatgag cgtggcgtga agattattgg cgcaaccgct cactatgtga
     4441 atgacaatct ggacgaaggt ccaatcatca tgcaggacgt tattcatgtc gatcatacct
     4501 acacagctga agatatgatg cgcgcaggtc gtgacgtcga gaaaaacgtc ttaagtcgtg
     4561 cgctatacaa agtactggcg cagcgcgtct ttgtttacgg taatcggacg attattcttt
     4621 aatcgtcagc caaaataact ggttagcttt aatccgttac ggatgaaaat cacgcaacca
     4681 gttcattttt ctcaacgtaa cactttacag cggcgcgtca tttgatatga tgcgccccgc
     4741 ttcccgataa gggagcaggc cagtaaaaag cattaccccg tggtggggtt cccgagcggc
     4801 caaagggagc agactgtaaa tctgccgtca tcgacttcga aggttcgaat ccttccccca
     4861 ccaccatcac tcgattccat tatcaaacct tcggcttctc ccccattcgc cgtaaaaact
     4921 gctgctgtag cctcaacaaa tccgctaacg tcaacaactg ataatccaga ccttgctggc
     4981 tggcaatttg cgcaataatg cggcttagcg ccgaataatg gcgatgatgc cagtgaggaa
     5041 acagatgatg ggtaaggtgc agattaatcc cacccagcca gtagccaagc catgcaggtt
     5101 gcggcgtcca atcaaaggtg gtagcaaagg tatgcgccag tctgcccacg ggcattttgc
     5161 cctcttctgg tggtaactgc gtatgtccct tcgcccagtg cgttccaata atcaacgtca
     5221 caaaaatcaa tgacgccagc agctggctga gcagataagt cagcaggatg gtcataaaac
     5281 taaaatcaga caaaagccag ggaattatca gacacagcgc acaatgcgcc agtttcccgg
     5341 ctaagaaata tccccagcca gcaaagcctc gcagggccag atgtcgcgtg accggcgtaa
     5401 accctgcgcg atcgagccag tccactaccc agatatacca gggaaaggtg agcgcggcga
     5461 ccagtggcca atagcgatgt tgctggcgca taaaaggtcg ccaccgttgc cacggcgtct
     5521 ggcgaagaat gccattttct gctgtatctg gatcgtaaaa ttcaatattg gtaaaaccgt
     5581 gatgaaagcg aacgtggcgc acccgccagc agtccggatc tagccccata ggaaaagcaa
     5641 cccaccggtt aagccgggca ttggtctttt taccacgcaa aaacgcatca tgcgaagcgt
     5701 catgcaccac attgaccgct aacaacatgg cgcaaaacat catcgcgaga taccacaaca
     5761 gatacagtcc ccattgacgt tgaaataacg ccagtaagta acaggagaaa caagcaataa
     5821 tcaacaccgc cattttgacg aatgcccatc cgtcggcata ccgatgatcg cctgatttcg
     5881 ccagataaac tttcgtaccg ctttgcagtt gtttcaccag ttgtggatca tcggcaggaa
     5941 aagtgattaa cctgtcggga ttaaacaggt tcatactgtt tccttagcga tttacgtcct
     6001 acgccgatta caaataacag gcaatgggcc agcagaatac ccactaatcc cttccagagc
     6061 agagtactcc atgaacacat atagacaata aaatagagca gtgacaacgt cacagagcac
     6121 cacaaaatca taccccaatg ctgcccgtcg ctcatgcccc ccagcgcaac ggagcctgcc
     6181 gccagcagaa caaataatac ggcttgctcg ctggtaataa actcaatgcc atagccatat
     6241 tgttgaatgt agccaagcac cagcataaac agcaggatca cccctgcccc taccgcccat
     6301 ggagaactct ggtagcgacc ttcaatcgct ttgccaaatg agcaaaagcc cattaagcgt
     6361 aaaaatggca gattactctc gcgcatcggg ttacaggaca agcgactatt ttttacgccg
     6421 tagcctacgt cgtattccgg cccggcacta tacgaaccga aaagtttatc ccacaacaaa
     6481 aaggtgccac cgtaattggt atcggcatat tgcttttgat tcagatgatg gacgcgatga
     6541 tgcgaaggcg tgatcagcac tttttccagc cagcccagtt tcggcgttag tgcgttatgg
     6601 ttaaaaaatt gccaactata gtgaataata gaaaccgcca aaaagacctg taacggcaca
     6661 ccaagcatcg ccagcagcat aaaaaacggg attgaggtta acgaggagta ccacgagttc
     6721 cgcacgccta atgacaggtt gtagtgttcc ccctgatgat gcaccacatg taccgcccac
     6781 agcgggcgca tttcgtgatg ccagcgatgt agccagtaaa agccgaaatc ccacgccagg
     6841 atagtaaaca accacagcag gatcaccggc acattatcaa acagtccaag gctgaagtga
     6901 ttgaccacca ggccatagca gagcacttcc aggcagcgaa ataaccacag catcatatga
     6961 ccggagttga tattaaaaat aacgtccagc cagtccactt tttgccgccc ggtgaattgc
     7021 aacacgcccg cttcggctaa caccaacagc accatcgata tgatggggaa taataaatca
     7081 ctcatattgt gtcttccttt tctcgcatgt tgcgcatatc caaccgcaaa tcgacgccag
     7141 caacgcgccg cctactaaat cgataaataa atgtctgcgt aattgcagaa tcgaaaaggc
     7201 gattgctatc gcccagacca cgctcattag cgtcagccaa cggttcccct ttttagcaat
     7261 cgcccatacc gccaacagcg ttagcgcggc gtgtaaggag ggaaaacagt tctggcttga
     7321 gtcaatggcg atcagcctgt tgagtgcgcc cgcggatatc cccatctgat caaacgaggg
     7381 ataatgcatg gttgtgggcc agagaagata aaatacgcca gccaccagtg cggaaatttg
     7441 cattgaacgg gccagccagc gcaggtggca aagtggcgtg gataaataac ctaacggcac
     7501 aatgaaaaaa aacgagagat acagccacac agcggagggg gaaaacgcaa tcaaattatc
     7561 aattattgac ggtgttaatt gatatccctc accttgcagg tagtcgctaa agttgtagat
     7621 aaccccaaca gttccccagc ccagcagcat ctgtttcagg cgtagcagtg aattgctcat
     7681 tcccgccccc actgacgcac aatgcgccgc cgcttggctg taaaagagac tggcacagtt
     7741 tgcagttcca gcgaccaaat taattgcccg acagcgatat cctggcgtat aaacaaggca
     7801 ttcaacgcct cccggcaatg ctccagcatc cacagctcgc aatcggcgat taacgtcaat
     7861 tgtgctgacc cggtttgtag caggcgataa tcgactgtta gcggcagtgt cattgccagc
     7921 acacgactac aggcatcggc aaaaacggtc tgaatatcgc cggatcttgt tggtagttgc
     7981 agttggtcat cctgccgccc ttcgatacgc gcaatcgcca ttgttgcact gccacagggg
     8041 catggctgtt cgcttgccac cagcacatca tccagtcgat aacgcactat cggctgtgtg
     8101 gtgcgggtaa agtctgtgac gatcggcacg aaacggtgct catccagcca ttgcggttca
     8161 atgtgaacaa actcttcgtt gagatgtaac gttccacacc ggcaggtgga agcgagaaag
     8221 ccttctgtcg cctgataaat ttcccccaca ttgtggaaca cgttgcgcag taattcccga
     8281 tcctgcggct ccagaacttc cgccaccgaa atcacttttt tgacctttag cgtcaattcg
     8341 ccggccatca cctccagcgc cagtgcgcgt aatacctgag ctggcgcgac aataatcgtg
     8401 ggcgctcgct gttggagaag tttgagttgc gcctgaaatg gcgctagcag atcgtaaaaa
     8461 tcgagactta accagcgatt attcacgctt tgatacaggt tgttgtccgc gcgcagaaac
     8521 agcgccaccc gctctttggc aaataaatca tcgggcaaca cttttgccag cacaccggcg
     8581 gcccacatct gttgctcgtg cgggctaaca acaaaaagtc cacgacgccc ggatgtacct
     8641 gatgaaagcc caacgctgaa cttaccaacg cagggtttga aatcacgact ctgctcactg
     8701 cgcattgcac aatcgagaag ttcgtcgcgc tttaaacctg cggtattcat ctcatcgaag
     8761 tgcgtcatca ttaacgcttt atccatcatt ggccactgat taaagggcaa cgtcagataa
     8821 cgctgaaacc acgggctatg agataagaca ttttgccgga actgatgcag cctttttgcc
     8881 tgccagtttt ccagtgcctc gcgatcggtg aaatgcagcc tgcgggtacg gaagtagcgc
     8941 cagatcaaca tcaacgggat cataaatccc cctcatggca caaacgaatc tccaccacac
     9001 cgttttgcca aagctgatgg agttgcccaa gcgtgtggta gtaggcgtgg ctgtcggaca
     9061 taaccagatg cgccagtggt gaaggccctc gcagctcccg gtagttagct ggcgcccatg
     9121 ccgcatcgcc agccagtaaa gtccagccgt tgtcggttaa cacaaacgcg ccaatatgtc
     9181 cggcagcatg tcctggaagc ggcacgagaa taatttcgcc attgctttct ggcagcaaat
     9241 agccgcactc aaacggtgcc agttgcgcgg gcaaattcac cgatgcgaaa ctttcaataa
     9301 agcgcagtga ggagtcaaaa ttctccggga ttagccctgg cacaaaggcc tggcgcagcg
     9361 cagtgacacc acgcagagtt cttacttgcc gccagccttc accagaacag atgcaggaaa
     9421 catcagggaa atcacgcagg ccagcaatat gatcagcgtg aaaatgcgac agaataatcg
     9481 catcaacatc tttcgctgcg aggccggtgg cagaaagttg tcgcaccagc gcctgttgcg
     9541 gatcgaaata aaccggcgtg acctggcgat aaagacgaaa cacaccagat tgcgtgtagt
     9601 gttcgaacca cgatgaatag cctgtgtccc acagccaccg tttgtcgccc acctccagca
     9661 gccaggcgcg ggcggggaat ttgcacactt tcagccctgc ccctttcagc gcaatacagc
     9721 taatatgggt acaccagccc gtttcaaatg cggttatttt tgccatgttc cctcagccat
     9781 tgtcccgtga ttgcaatacc ttgttccatc gaaaagcgtg ggcgatatcc cagctctgta
     9841 atggcctttt gcgcactcag cgtcatatcg aaacagagtg ttccggcgct gtatcgtgtg
     9901 ataacaggtt cctgattaac gcacttccca tacagttcca ggccacgcgc gatcagagaa
     9961 agcagcgacc agggaacagc agcaatgcgg taactcaagc ccagttgctg gtgcagcaag
    10021 gcgtcaagca tcaccgatag ctgctgcggc tggtgattgc tgatgttgta aatactgccc
    10081 gagcgtaagc cttcaacgtt cgttgccagc cgcatggcat acaccacgtt ttgcacgaac
    10141 gtgagatcca ataacgcgtc gcccccgcgc ggcaaacgta agcaaccgcc gccctgttgc
    10201 aattgctgca tcagacgagg aacaattacc tggtcatggg ggccaaacaa accacgggga
    10261 cgcaaaagaa taaatctcgt ggcagaatat cgagaaacag cgccagcaat aacctgctca
    10321 gcggcatatt tactgctggc ataatggctg gagaatgctc gcgcaagata agtttctggc
    10381 aggtcatagt gatgttgaaa atcaaagtaa accgcaggcg tggagatatg gataaaccgg
    10441 ggaatattca gcctgcctgc cgcctgtgcc agagtgtggg tcactttgac attggcaagc
    10501 cagaacgccg ttttgtcgcc ccagggcgag gactttgccg cacagtgcca gacggcatcg
    10561 cagccgtcca tcaggcgggc gcagtcatcc tcggttgcct cggttaaatc gagagccaca
    10621 aactgtgcgc ctgcgtttgt caggcttctg ccaacctcac aatttcgccc tgttgccaca
    10681 accgactcac ccgattgcaa caaatattgc acggcatttc gcccaaggcc gctggtcgcc
    10741 cctgttacga ggatcttcac ggtaaaagca ccatgccagc cagcgttagt cccgctgccg
    10801 tgccaatcaa cattacaggt ttatccgctg tgaaacgacc gctaatcact gcttcatgca
    10861 gcgccgtggg gatagaggcc gcgacctgat tgccgtaaaa acgatacaca tcgatgagcg
    10921 cagattccgg cactcgcagc cgtttacgca tatgttcaag ggaaagatga ctggcctgat
    10981 gcggaacgac cgtgccgata tcagacagtt gcaggctgct tttttgcagc aaccgagaaa
    11041 aataatcttc aataagcgaa gaagcaaaac gaaacagcgg tttcccctgc atatgaaaaa
    11101 gaaagtcgct atcactcaca ccagagcgag gattacgccg cgtaccgcca gcacgaattt
    11161 cacacagttc gctgccttcg ggatacattt cgatcaggct agcgataatc ccgctgcgcc
    11221 catcgccccg ctcaacaatc gcgcacgccg cgccatcacc aaaaattaat gaagactctt
    11281 catgatccca gtcgataccg cgtgaagcaa tatctgccga aacgatggca atgcgtcgat
    11341 atgctccaca gtttaataat ccggcagcga cttcaagagc ggaaataaag ctcacacagc
    11401 tactgttgat atcaaacccg gcaacgccta cgggcatggc tgcggcttta agaatatgaa
    11461 ttgcgctaca gggtaatgcc tgtacggcaa tggccgatgc acaaattagc agatcaatat
    11521 cagaaggatt taaggctgcc gctactaacg cattatgtaa agcctctgcc gccagttcgg
    11581 cctggctggc gtcgttgcgg gcaaaatagc gccagcaaat accggaacgt cgctcaacat
    11641 agccaactgg cttatttaac tgaacatcca gttgtttaga agtgatttga tcagggggta
    11701 aggcgatccc cgtggcgatt atttttaacg ccgcggagat cgtcggttga ttaggtcgag
    11761 ccacggtcag tgctccttca ctgctccata ggtggaccaa tcatatagat gaagtacgtt
    11821 tccctacaat ccgaaaaatc ggcagtgtgt aaccgccgat gtttggttta gataatgttt
    11881 ggtttagata attagtgacg agcgcgcacc agctgatact tacgcgtcag atactccacc
    11941 gggacactcc agatgtgtac cagacgcgag aacgggaaca gcaggaataa cgtcatcccc
    12001 aacaccaggt gcagacggaa gataaacgcc acgccatcaa gatgttgaga agcgccaccg
    12061 tggaaggtca ctaccgactg cgcccagcca accagtttca tcatctcgct accgtccata
    12121 tgctgagcag agaacggaat ggtcagcagg cccagcgcgc actggataac gagcagcgac
    12181 aggatcagga tatccgctcc ggtagtcgtt gcacgcacgc gtgggctgaa cagacggcgt
    12241 ttcaacaaca gcacgccgcc aatcagacac agtacgccgc tggcaccacc agcaaacatc
    12301 gccattttct gcttcacttc aatcggcagc caggcttcat acatccagtg cggcgtcagc
    12361 ataccgaaga agtgaccgac aaaaatcccc agaataccga tatggaacag gttcgacgcc
    12421 agattcatcc ctttgcgatc cagcatctgg ctggacgccg cgcgccaggt atactgcccg
    12481 tagtcataac gcagccagct accaatcagg aagaccgccc cggctatgta cgggtagata
    12541 tcaaagaaga acatattcag gaattgcatt agtgctgtcc tccggtggtg atattcagat
    12601 attgcggcgc gacggcaccg gcaaagcgac gctgatgagc agtgattgct gaatcaccgc
    12661 agcctttgtc agcaaagaat ttaacctgct cttcttccca gactgcatcc agcgcctgcg
    12721 gcgtatcgtc gcgcgcttcg tcggcaattt tttccgccac tttgtcgctg tcgattgcgg
    12781 tattcgccag tttcagcagc agatcaaaca gcacggcata acggctttca cgctgttgca
    12841 gacgcgcact cagcaatgcc agaatcggcg caatatcttt caaaccctcc acggcttcgc
    12901 tttgcggcag ctgcgccagg tactccagat acagcggcag atggtcgggc aattcgcggc
    12961 tgtttaactg caagccgtgc tgctcgtact gcgccagcag atccaccatc gcctggccgc
    13021 ggtcacggga ttcaccgtga acatgttcaa atagcaacag tgacgtggcg cggccacggt
    13081 cgaacagttc gctgtactgc gcctgggcat cgagcggatc catcgtcgtt aaatcgcgca
    13141 ggaaaatgcc cagcgcatgg gcatcctctt ttggcagatt tttcgacgcg gcaatcgcct
    13201 caaacatctc ttgttgatgc tgccataagg cagcatccgg atattcaagg agacgcgata
    13261 caatcacgag ttcgatcatg ggtgcggctc cgttttgctg gttacgtcga tggcatcgat
    13321 acggcggctg ttgaacagat tgaatttggt atctgaaccg tggcagccat caccaaaggt
    13381 aaagccgcag ccatttttct ccgggaaggc ttcccgcgcc agttcacgat gactgctcgg
    13441 caccacaaag cgatcttcgt agttggcaat agccagataa cgatacatct cctgtgcctg
    13501 ggcttcggtc agaccgacct cttccagcgc acgggtatcg actttaccgt caacggtttc
    13561 agcacgtttg taatgacgca tcgccagcat acgtttcagc gcgcgcagta ccggtttggt
    13621 atcaccggcg gtcagcagat tcgccagata ctgtaccgga atacgcaggc tttcgacgtc
    13681 tggcagaatg ccgttgctgc ccagttcacc cgcgtctgcc gcagactgaa tcggcgacag
    13741 aggcggcacg taccagacca tcggcaatgt gcgatattcc ggatgcagcg gcagcgccag
    13801 tttccattcc atcgccattt tataaactgg cgactgctgc gcagcctcaa taacgctcag
    13861 cggaataccg tctttaatcg cctgctcgat gactttcgga tcgttcggat cgaggaacac
    13921 atccagctga cgctggtaga gatctttctc gttctcggta cttgccgcac gttcaatcgc
    13981 gtcggcatcg tacagcagca cgccaagata acggatacga ccgacacagg tttctgaaca
    14041 tattgtcggc tggccggctt caatacgcgg atagcagaag atgcacttct cagacttacc
    14101 gctcttccag ttgaagtaga tttttttgta cgggcatccg gtgatgcaca tacgccagcc
    14161 acggcattta tcctggtcga tcaggacgat gccgtcttct tcacgcttgt aaatcgcacc
    14221 gctcgggcag gtcgccacac atgccgggtt cagacagtgt tcgcacaggc gcggcaaata
    14281 catcatgaag gtgttttcga actggctata catcgccttc tggatgttgt cgaagttctt
    14341 gtctttcgcc agcttgtcaa actcaccgcc caggtcatct tcccagttcg gccctttttc
    14401 gattttcgcc atccgttcgc cggtaatcag cgaacgcgga cgggcaatcg gctgtgattt
    14461 gctgccttcc ggcgcggtat gcaggttctg ataatcaaaa tcaaacggct cgtaataatc
    14521 gtcgatcccc ggcagatgcg ggttagcgaa gattttaccc agcagcatgg cacggttacc
    14581 catgcgcggc tgcagtttgc cgttgatttt acggatccag ccgcctttgt atttttcctg
    14641 gttttcccag tcagtcggga agccctggcc cggcttggtt tccacgttgt tgaaccacgc
    14701 gtattccacg ccttcacggc tggtccagac gtttttacag gtcactgaac aggtgtggca
    14761 gccgatgcac ttatcgagat tcagcaccat gccgacttgt gaacgaattt tcattttacg
    14821 ctctcctgta cctggtcatt gccttcgcca tctaaccagt caatgttctt catcttacgc
    14881 actacaacaa actcatcgcg gttagaacct acggtgccgt agtagttaaa gccatatgcc
    14941 agatgggcat agccgccgat catatgcgtc ggtttcggcg tgatacgggt gaccgagtta
    15001 tggataccac cacgctgttg ggtaatttcc gaaccaggca ggttaacgat acgttcctgc
    15061 gcgtggtaca tcatggtcat ccctgccgga acacgctggc tgacaaccgc acgggcagtc
    15121 agtgcaccgt tgctgttgaa gacttcaatc cagtcgttat cggcgatacc cagctctttg
    15181 gcatcggctt cactcagcca gaccaccgga ccaccgcgac ctaaagtcag catcaacagg
    15241 ttgtcgctgt aggtggagtg gataccccac ttctggtgtg gcgtcaggaa gttgagcgct
    15301 ttttccgggt tgccattgga tttctggccc atcacttctt tcaccgaacg ggtgtcgatc
    15361 ggcggacgat aaaccagcag gctttcaccg aaatcacgca tccattggtg atcctgatac
    15421 agctgctgac ggccagagag cgtacgccac gggatcagct cgtgaacgtt ggtgtaaccg
    15481 gcgttgtaag aaacgtgttc atcttcaagg ccagaccatg tcgggctgga gatgattttg
    15541 cgcggctgtg cctgaatatc gcggaagcga atcttctcgt cttctttatt cagcgccaga
    15601 tgcgtatggt cacggccggt aaactcgctc agggcagccc aggcttttac agctacctga
    15661 ccgttggttt ccggtgccag cgtcaggatc atctctgccg catcaattgc ggtattgagc
    15721 atcggctgac cttttgccgg accttccgct tttgtgtagt tgagcttacg cagcagatcc
    15781 atctcgctct gggtgttcca ggcaatccct ttaccgccgt taccgatttt ctccatcagc
    15841 gggccgatag aggtaaagcg ttcgtaagtt gccggataat cgcgctctac gaccataatg
    15901 tgcggtgcgg ttttacctgg gatcaggtcg cattcgcctt ttttccagtc tttcacatcc
    15961 agcggttgcg ccagttcagc ggcagagtcg tgctggatag gcagcgtgac gatgtcagtt
    16021 tctttaccca gatgaccaac gcacacttcg gagaatttct tcgcgatggc tttgtagatt
    16081 tcccagtcgc ttttcgcttc ccaggccgga tcgaccgccg cagacagcgg gtgaataaac
    16141 ggatgcatat ccgaagtatt catgtcgtct ttttcgtacc aggtcgccgt cggcaaaatg
    16201 atgtcggaat agagacaggt gctcgacaga cggaagtcca gcgtcaccac cagatccagc
    16261 ttgccttcca gaccgttgtc ctgccagtcc acttcttccg gcttcacgcc gccctgctgc
    16321 cccaggtctt tgccctggat accgtgctcc gtccccagca ggtacttgag cataaactca
    16381 tgacctttac cggaagaacc gagcaggtta gaacgccaga tgaacaggtt acgcgggtgg
    16441 tttttaccgt tttccggctg ttccgcagcg aaacggatag aaccctcttt cagggatttc
    16501 accgtatagt ccaccggatt catcccggct ttttctgctt cgcgagcgat agtcagcggg
    16561 ttagtgccta actgcggcgc agacggcagc cagcccatgc gttctgcacg gacgttaaag
    16621 tcgatcaagt gtccggtata gcgagattta tccgccatcg gcgacagcag ttcttccgca
    16681 gtcacggttt cataacgcca ctggctggag tggttataga aataagaggt actgttcatg
    16741 tgacgcgccg gacgctgcca gtcgagggca aacgccagcg gctgccagcc ggtttgcgga
    16801 cgcagttttt cctgacctac atagtgcgcc cagccgcccc cgctctgacc gacacaaccg
    16861 cagaaaatca gcatgttgat cagaccacga tagttcatgt ccaggtgata ccagtggttc
    16921 agccctgcgc cgacgataat catcgaacga ccgtgcgttt tatcagcgtt atcggcaaat
    16981 tcacgggcga tgcgaataat ctggctgcga gaaacgccgg taatctgctc tgcccaggca
    17041 ggggtgtaag ctttcacatc gtcatagctg gttgcacagt taacgtcgtt caggccacgt
    17101 tccagaccgt agtttgccag cgtcagatca taaacggtgg tcaccagggc ggtgctgcca
    17161 tcagccagtt gcaggcgttt caccggcagc ttatgcagca gcacgttttc cagttccact
    17221 ttgttgaagt gttccgtgcc atcgccacca aagtacggga agcccacctc agcgatctca
    17281 tcctggctac ccagcaggct cagttgcagc tcggtttctt cgccagtttt gccgtcgcgc
    17341 tgctcaagat tccatttgcc cttctcgccc cagcggaagc caatagaacc gttcggcgca
    17401 accatttcac cattggtatt aaaggcgaca gttttccatt ccggattgtt ttcctggccc
    17461 agtgcatcca ccagatcagc agcgcgcagc atacgacccg cagcgtagta accgtcgcgc
    17521 tcttccagca tcaccagcat cggcatgtcg gtgtagcggc gcacatagtc ggtgaaatac
    17581 tggcttgggt tgtcgaggtg gaattcacgc agcattacgt gacccattgc cagcgccatt
    17641 gccgcatcgg tgccctgttt cggtgccagc cacagatcgc acagtttggc gatttcagcg
    17701 tagtctggtg tgacggcaac agttttggtc cctttgtaac gcacttcagt aaagaagtga
    17761 gcatccgggg tacgcgtctg cggcacgttt gaaccccagg cgatgatgta gctggagttg
    17821 taccagtcag cagattccgg tacgtcagtt tgctcacccc aggtttgcgg agacgcagga
    17881 ggcaggtcgc agtaccagtc gtagaagctt aagcaagtac cgccaatcag cgagagatag
    17941 cgcgcacccg atgcgtaaga aaccatcgac attgccggaa ttggcgagaa gccagcgaca
    18001 cggtccgggc cgtaattttt gatggtgtaa acgttagatg cggcgatcag ttcgttcact
    18061 tcctgccagg aagaacgaac aaaaccaccg cgtccacgcg cctgcttaaa gcttttcgct
    18121 ttatcggcgt cttcaatgat agaagcccat gcctcaaccg gatcgctatg cagcgccttc
    18181 gcttcacgcc acattttcat caggcgtttg cgcatcatcg ggtatttcag gcggttagcg
    18241 ctgtaaagat accaggagta gctggcaccg cgcgggcagc cgcgaggttc atggtttggc
    18301 aggtccgggc gagtacgcgg atagtcagtc tgctgggttt cccaggtgac cagaccgttt
    18361 ttgacgtaga ttttccagct gcaggagccg gtgcagttta ccccgtgggt agagcggacg
    18421 attttgtcat gctgccaacg ctggcgatat ccatcctccc agtcacggtt ggtattgaga
    18481 agctggccat gcccatcggc aaaggtttca cccttctgtt tgaagtagcg aaaccggtcc
    18541 aggaatttac tcatcggttt tctcctgtgg gagcctgtcg gccctctgat aaatcgacat
    18601 tgctaatgtt taagggcaag gtaacgctct gaaacagcgt gggaattgat aacgatcaag
    18661 agtgatgggg atgaaaaata aagtaaattc ctggaatacc cctt
//
LOCUS       DAFGPF010000093        18633 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFGPF010000093 DAFGPF010000000
VERSION     DAFGPF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18633
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.093"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            140..1279
                     /gene="arnB"
                     /locus_tag="LSX49_003667"
     CDS             140..1279
                     /gene="arnB"
                     /locus_tag="LSX49_003667"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HBL7170027.1"
                     /translation="MSGFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DRDTLMVTPEAIEAAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     HTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALATLPF
                     QPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ"
     gene            1283..2251
                     /gene="arnC"
                     /locus_tag="LSX49_003668"
     CDS             1283..2251
                     /gene="arnC"
                     /locus_tag="LSX49_003668"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HBL7170028.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTAACESLGKEYEIL
                     LIDDGSSDNSAHVLVEASQAEGSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            2251..4233
                     /gene="arnA"
                     /locus_tag="LSX49_003669"
     CDS             2251..4233
                     /gene="arnA"
                     /locus_tag="LSX49_003669"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HBL7170029.1"
                     /translation="MKTVVFAYHDMGCLGIEALLSAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKALPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NARRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS"
     gene            4230..5120
                     /locus_tag="LSX49_003670"
     CDS             4230..5120
                     /locus_tag="LSX49_003670"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HBL7170030.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHE
                     VGLHAWDHHAWQAHSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGTPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRIQRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGTLPLGQVV
                     RGNIAGREGWLGCQQMAGSH"
     gene            5120..6772
                     /gene="arnT"
                     /locus_tag="LSX49_003671"
     CDS             5120..6772
                     /gene="arnT"
                     /locus_tag="LSX49_003671"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HBL7170031.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALMTWFT
                     LRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYLPVIIAGSLPWLGLLP
                     GALYAGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFAPLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRDEDINSLAIPPADAIDRQGRLVLIQYRPK"
     gene            6769..7104
                     /gene="arnE"
                     /locus_tag="LSX49_003672"
     CDS             6769..7104
                     /gene="arnE"
                     /locus_tag="LSX49_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HBL7170032.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFAAVNKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSLRHWCGVAFIIG
                     GIVILGSTV"
     gene            7104..7490
                     /gene="arnF"
                     /locus_tag="LSX49_003673"
     CDS             7104..7490
                     /gene="arnF"
                     /locus_tag="LSX49_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416761.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HBL7170033.1"
                     /translation="MGLMWGLFSVIIASAAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPTTKQRY"
     gene            complement(7484..7750)
                     /gene="pmrD"
                     /locus_tag="LSX49_003674"
     CDS             complement(7484..7750)
                     /gene="pmrD"
                     /locus_tag="LSX49_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311174.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HBL7170034.1"
                     /translation="MEWLVKKSCCNKQNNRHVLMLCDAGGAIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASCYSPDEWERQCKAAGKTQ"
     gene            complement(7860..9215)
                     /gene="menE"
                     /locus_tag="LSX49_003675"
     CDS             complement(7860..9215)
                     /gene="menE"
                     /locus_tag="LSX49_003675"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HBL7170035.1"
                     /translation="MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASSF
                     AAQGVVAGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPEGENTFPALTSLHIQQVEGVHAVAWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAEGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNDEVWLRAASMAEGYWRNGQRVPLVNDEGWYAT
                     RDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVVEYDQQTVDLGEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQ
                     D"
     gene            complement(9212..10174)
                     /gene="menC"
                     /locus_tag="LSX49_003676"
     CDS             complement(9212..10174)
                     /gene="menC"
                     /locus_tag="LSX49_003676"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HBL7170036.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEDAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     PDFAFVAEEGVRAVVIKPTLTGSLEKVREQVKAAHALGLTAVISSSIESSLGLMQLAR
                     IAAWLTPDTIPGLDTLDLMQVQQVRRWPGSPLPLVDVDALERLL"
     gene            complement(10174..11031)
                     /gene="menB"
                     /locus_tag="LSX49_003677"
     CDS             complement(10174..11031)
                     /gene="menB"
                     /locus_tag="LSX49_003677"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HBL7170037.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(11046..11804)
                     /gene="menH"
                     /locus_tag="LSX49_003678"
     CDS             complement(11046..11804)
                     /gene="menH"
                     /locus_tag="LSX49_003678"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HBL7170038.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLY
                     VDLPGHGGSATISVDGFDDVTDLLCKTLVSYNILNFWLVGYSLGGRVAMMAACQELAG
                     LCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQ
                     RRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAADCHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(11801..13471)
                     /gene="menD"
                     /locus_tag="LSX49_003679"
     CDS             complement(11801..13471)
                     /gene="menD"
                     /locus_tag="LSX49_003679"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HBL7170039.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     SAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGISWQQRLGDWWQDDKPWLREAPRRESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     ELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKSERGRFYLMPQNVHFEHAAAMFELKY
                     HRPQNWQELETTLVDAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13560..14855)
                     /gene="menF"
                     /locus_tag="LSX49_003680"
     CDS             complement(13560..14855)
                     /gene="menF"
                     /locus_tag="LSX49_003680"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HBL7170040.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQVYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGYLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIKAKEFIATLVSIKPLPGLHLTT
                     TREQHWPDKTGWTLLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTRTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNIVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(14934..15239)
                     /gene="elaB"
                     /locus_tag="LSX49_003681"
     CDS             complement(14934..15239)
                     /gene="elaB"
                     /locus_tag="LSX49_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HBL7170041.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15294..15755)
                     /locus_tag="LSX49_003682"
     CDS             complement(15294..15755)
                     /locus_tag="LSX49_003682"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL7170042.1"
                     /translation="MIDWQDLHHSDLSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     EGENRHILGWHNGTLVAYARILKSDDELQPVVIGRVIVSEALRGEKIGQQLMSKALES
                     CTRRWPEKPIYLGAQAHLQNFYGQFGFIPVTDIYEEDGIPHIGMAREVIQA"
     gene            15820..16737
                     /gene="rbn"
                     /locus_tag="LSX49_003683"
     CDS             15820..16737
                     /gene="rbn"
                     /locus_tag="LSX49_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311183.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HBL7170043.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPHGIREFVE
                     TALRISGSWTDYPLEIVEISTGEIFDDGLRKVTAYPMEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQELKAGKTIMLDDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALELAKGVDVMVHEATLDMAMEAKANSRGHSSTRQAAALAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFAVFSI"
     gene            complement(16858..18600)
                     /locus_tag="LSX49_003684"
     CDS             complement(16858..18600)
                     /locus_tag="LSX49_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL7170044.1"
                     /translation="MRNKNIIMLLISSLILSGCGPEPEDKKSQQQQSTTPTDQQVLAA
                     QQAATKVAEQSAAKAAADAKALAQQEVQQYSDKQALLGRLQAAPKYQHAAREKAASQI
                     ANPATARYQQFDDNPVKQVAQNPLATFSLDVDTGSYANVRRFLNQGLLPPPDAVRVEE
                     IVNYFPSDWDIKDKQSIPASKPIPFAMRYELAPAPWNEQRTLLKVDILAKDRKSEELP
                     ASNLVFLIDTSGSMISDERLPLIQSSLKLLVKELREQDNIAIVTYAGDSRIALPSISG
                     SHKAEINAAIDSLDAEGSTNGGAGLEMAYQQAAKGFIKGGINRILLATDGDFNVGIDD
                     PKSIESMVKKQRESGVTLSTLGVGDSNYNEAMMVRIADVGNGNYSYIDTLSEAQKVLN
                     SEMRQTLITVAKDVKAQIEFNPAWVTEYRQIGYEKRQLKAEDFNNDNVDAGDIGAGKH
                     ITLLFELTLKGQKASIDKLRYAPDNKSAKSDKTKELAWLKIRWKSPQGKESQLVEFPL
                     ASAIKAPSEDMRFRAAVAAYGQKLRGSEYLNNTSWQQIKQWAQKAKGEDPQGYRAEFI
                     RLIGLAKDLDNSQN"
BASE COUNT         4311 a         5005 c         4699 g         4618 t
ORIGIN      
        1 aatatttacg tctaatatta gtttcttaag gttaagttaa tattctatcc ttaaaatttt
       61 gctccaaatg gcaaaatata cacaacactc tttatagcaa atataagtgg acaggtattc
      121 aatgacggat ggaaaaacaa tgtcaggatt tttgcctttt tcgcgaccag caatgggcgt
      181 agaggaactc gctgcagtta aagaggttct cgaatccggt tggatcacaa ccggtccgaa
      241 gaatcaggcg cttgaacaag ctttttgcca gttgacggga aatcagcatg ccatcgcggt
      301 cagttcagcc accgccggaa tgcatatcac gctaatggcg ttggaaattg gcaagggcga
      361 tgaagtgatt acgccttccc tgacctgggt ttcaaccctc aatatgattt ccttgctggg
      421 tgcaacgccg gtaatggtgg atgtcgaccg cgatacgctg atggtcacgc ctgaagcgat
      481 cgaagcagcc attacaccac gcactaaagc catcattccg gtgcattatg ccggtgcgcc
      541 agcagatatt gacgccattc gcgccattgg cgaacgttac ggcatcgcag ttatcgaaga
      601 tgctgcccat gccgtaggta cgtattacaa agggcgacat attggcgcaa aaggtaccgc
      661 tattttttcg tttcacgcca tcaaaaatat tacctgtgcg gaaggtggcc tgattgttac
      721 tgataatgaa aatcttgccc gccagctgcg gatgctgaaa tttcacggtc tgggtgtcga
      781 tgcctatgac agacatacct ggggccgtgc accgcaggct gaagtcttaa cgccgggcta
      841 taagtacaat ctgaccgata ttaacgccgc gattgccctg acacagttag tcaaattaga
      901 gcacctcaac acccggcggc gcgaaattgc ccagcaatat cagcaagcac tggcaactct
      961 cccctttcag ccattaagcc ttcccgcctg gccgcacgtt cacgcctggc atctgtttat
     1021 tattcgtgtc gatgaacaac gttgtggtat cagtcgcgat gcgttgatgg aagcgttaaa
     1081 agaaagaggc attggtaccg ggttacattt ccgcgctgct cacacacaaa aatattatcg
     1141 cgagcgtttt cccacgctgt cgttaccgaa taccgaatgg aatagcgaac gcatctgttc
     1201 attgccgctg ttcccggata tgaccaccgc cgatgccgac cgcgtcatca cagcccttca
     1261 gcaactcgca ggacaataag ccatgtttga aatccaccct gttaagaaag tctcggtggt
     1321 tattcccgtt tataacgagc aggaaagctt accggaatta atcaggcgca ccaccgcagc
     1381 ctgtgaatca ctggggaaag agtatgaaat cctgctgatt gatgacggca gtagcgataa
     1441 ttccgcgcat gtgctggtcg aagcctcaca agcggagggc agccatattg tgtctatttt
     1501 gcttaaccgc aattacgggc aacattcagc gattatggcg ggattcagtc acgtcaccgg
     1561 cgacttaatt attaccctcg atgccgatct ccagaatccg ccagaggaga tcccccgtct
     1621 ggtggcaaaa gccgatgaag gttacgacgt ggtagggact gtacgccaga accgccagga
     1681 cagctggttt cgtaaaaccg cttcgaagat gattaaccgg cttattcagc gcaccaccgg
     1741 caaagcgatg ggtgactatg gttgtatgct gcgcgcctat cgccgtcata ttgtcgatgc
     1801 gatgttgcac tgccatgaac gcagcacctt tatcccgatt ctggcgaata tcttcgcccg
     1861 ccgtgccatt gaaattccag tgcaccatgc cgagcgtgag tttggtgaat ccaaatacag
     1921 ctttatgcgc ctgattaatt tgatgtacga cctggtgacc tgccttacca caacgccgct
     1981 acgtatgttg agtttgctcg gcagcattat tgcgattggc ggttttagca ttgcggtgct
     2041 gctggtgatt ttacgcctga ccttcggacc acaatgggcg gcagaaggcg tctttatgct
     2101 atttgccgtg ctgtttactt ttattggcgc tcagtttatc ggcatgggat tgctcggtga
     2161 atatatcggc aggatctaca ccgatgtccg cgcccgcccc cgctattttg ttcagcaagt
     2221 tatccgtcca tccagcaagg aaaatgaata atgaaaaccg tcgtttttgc ctaccacgat
     2281 atgggatgcc tcggtattga agccctgctg tctgccggtt acgaaattag cgccattttt
     2341 acccatactg ataaccccgg tgaaaaagcc ttttatggtt cggttgcccg actggcagcg
     2401 gaaagaggca ttccagttta tgcgccggat aacgttaatc atccgctgtg ggtggaacgc
     2461 attgcccaac tatcaccaga ggtgattttc tctttttatt atcgccatct tatttgcgat
     2521 gagattttgc agctcgctcc gagaggtgca tttaatctgc atggttcgct gttaccaaaa
     2581 tatcgtggtc gcgcgccgct gaactgggtg ctggtgaacg gtgaaacgga aactggcgtt
     2641 acattgcacc gaatggtgaa acgtgccgat gccggggcca ttgtggcaca actgcgcgtt
     2701 gccattgcgc cagacgatat cgccattacg ctgcatcata aattgtgcca tgccgcgcgc
     2761 cagctactgg aacagacatt acccgccatt aaacacggta atattctgga aatcgcccag
     2821 cgcgaaaacg aagccacctg ttttggtcgc agaacgccgg atgacagttt cctcgaatgg
     2881 cataagccgg catccgtact gcacaacatg gtgcgtgccg ttgccgatcc gtggccgggt
     2941 gccttcagct atgttggcaa tcagaaattc accgtctggt cgtcgcgtgt tcatcctcat
     3001 gccagcaaag cactgccggg gagcgtgatt tctgttgcac cactgctgat tgcctgtggc
     3061 gatggcgcgc tggaaatcgt cactggacag gcgggcgacg gcattactat gcagggctcg
     3121 caattagcgc agacgctggg cctggtgcaa ggttcacgct tgaatagcca gcctgcctgt
     3181 gccgcccgac gccgtacccg ggtactcatc ctcggggtga atggctttat tggcaaccat
     3241 ctgacagaac gcctgctgcg cgaagatcat tatgaagttt acggtctgga tattggcagc
     3301 gatgcgataa gccgttttct gaatcatccg cattttcact ttgtcgaagg cgatatcagt
     3361 attcattccg aatggattga gtatcacgtc aaaaaatgtg atgtcgtgtt gccgctggtg
     3421 gcgatagcca cgccgattga atatacccgc aacccgctgc gcgtatttga actcgatttc
     3481 gaagagaatc tgcgcattat ccgctactgc gtgaagtacc gtaagcgaat catcttcccg
     3541 tcgacttcag aagtttatgg gatgtgtagc gataaatact tcgatgagga tcattctaat
     3601 ttaatcgtcg gcccggtgaa taaaccacgc tggatttatt cggtgtctaa acaattactt
     3661 gatcgggtga tctgggccta tggcgaaaaa gaaggtttac agttcaccct cttccgcccg
     3721 tttaactgga tggggccacg actggataac cttaatgcag cgcgaattgg cagctcccgc
     3781 gctattacgc aactcattct caatctggta gaaggttcac cgattaagct gattgatggc
     3841 ggaaaacaaa aacgctgctt tactgatatt cgggatggta tcgaggcgtt ataccgcatt
     3901 atcgaaaatg cgggaaatcg ctgcgatggc gaaattatca acattggcaa tcctgagaac
     3961 gaagcgagca ttgaagaact gggtgagatg ctgctggcga gcttcgaaaa acatccgctg
     4021 cgccattact tcccaccgtt tgcgggcttt cgtgttgtcg aaagtagcag ctactatggc
     4081 aaaggatatc aggacgtaga gcatcgtaaa ccgagcatcc gcaatgcccg ccgctgcctg
     4141 gactgggaac cgaaaattga tatgcaggaa accatcgacg aaacgctgga tttcttcctg
     4201 cgcaccgttg atcttacgga taaaccatca tgaccaaagt cggcttacgc attgatgtcg
     4261 atacctttcg tggcacccgt gaaggcgtgc cgcgtctgct ggaaatcttg agtaagcata
     4321 atattcaggc cagcattttt ttcagcgtcg gcccggacaa tatgggccgc catctctggc
     4381 gactggtgaa gccacagttt ttgtggaaga tgctgcgctc aaacgcggca tcgctttatg
     4441 gctgggatat tttactggca ggtacggcct ggccaggtaa agagattggt catgccaatg
     4501 ccgatatcat tcgtgaagcg gctaaacatc acgaagtcgg cctgcacgcc tgggatcacc
     4561 atgcctggca agcccatagc ggtaattggg atcggcaaac aatgatcgac gatattgcac
     4621 gcggccttcg caccctggaa gagattatcg gtcaaccggt aacctgttct gccgctgctg
     4681 gctggcgtgc tgaccaacag gtgatcgaag caaaagaagc gttccatttg cgctacaaca
     4741 gcgattgtcg tggggcgatg ccgtttcgtc cattgctcga atcaggaacc cccggcactg
     4801 cgcaaattcc ggtgacctta cccacctggg atgaagtgat tggtcgggat gtgaaagcag
     4861 aagattttaa cggttggtta ctcaaccgca tccagcgaga taaaggcacg ccggtttata
     4921 ccattcatgc cgaagttgaa ggctgcgctt atcagcataa ttttgtggat ctcctgaaac
     4981 gcgcagctca ggaaggcgtg acattttgcc ctttaagcga actgttatca gggacgttgc
     5041 cgctcggaca agttgttcgc ggaaatattg ccggacgtga aggctggctg ggttgccaac
     5101 aaatggcggg tagtcactga tgaaatcggt acgttacctt atcggcctct tcgcatttat
     5161 tgcctgctat tacctgttac cgatcagcac gcgtctgctc tggcaaccag atgaaacgcg
     5221 ttatgcggaa atcagtcggg aaatgctggc atccggcgac tggattgttc cccatctgtt
     5281 agggctacgt tatttcgaaa aacccattgc cggatactgg attaacagca ttgggcaatg
     5341 gctatttggc gcgaataact ttggtgtgcg ggcaggcgtt atctttgcga ccctgttaac
     5401 tgccgcgctg atgacctggt ttactctgcg cttatggcgc gataaacgtc tggctttact
     5461 cgccacagta atttatctct cattgtttat tgtctatgcc atcggcactt atgccgtgct
     5521 cgatccgttt attgccttct ggctggtggc gggaatgtgc agcttctggc tggcaatgca
     5581 ggcacagacg tggaaaggca aaagcgcagg atttttactg ctgggaatca cctgcggcat
     5641 gggggtgatg accaaaggtt ttctcgccct tgccgtgccg gtattaagcg tgctgccatg
     5701 ggtagcaacg caaaaacgct ggaaagatct ctttatttac ggctggctgg cggttatcag
     5761 ttgcgtactg acggttctcc cctggggact ggcgatagcg cagcgggagc ctgacttctg
     5821 gcactatttt ttctgggttg agcatattca acgctttgca ctggatgatg cccaacatag
     5881 agcgccgttc tggtactact tgccggtcat cattgccggt agcctgccgt ggctgggatt
     5941 actccccggt gcactgtacg ctggctggaa aaaccgcaag cattccgcaa ccgtttattt
     6001 gttgagctgg acgataatgc cgctgctgtt tttctccgtc gctaaaggca aattgcccac
     6061 ctatattctt tcctgctttg cacctctggc aatgctgatg gcgcattacg ctttgctggc
     6121 agcaaaaaat aatcctctgg cgttgcggat taatggctgg attaacatcg cttttggcgt
     6181 cactggcatt attgccacat ttgtggtctc cccctgggga ccaatgaaca caccggtgtg
     6241 gcaaaccttc gagagctata aagtcttttg tgcctggtct attttttcgc tatgggcatt
     6301 tttcggctgg tacaccttaa caaacgtcga aaagacctgg ccttttgccg cgctttgccc
     6361 gctggggctg gcgttgctgg taggattttc aattcctgac agagtcatgg aaggaaaaca
     6421 tccgcaattt tttgtcgaga tgacacaaga atcacttcag ccaagccgct atattcttac
     6481 tgatagcgtc ggtgttgccg caggtctggc atggagcctg caacgcgatg acatcatcat
     6541 gtatcgccag acaggtgagt tgaaatatgg ccttaattat ccggatgcaa aagggagatt
     6601 tgtcagcggt gatgagttcg caaactggct taatcaacat cgtcaggagg ggattattac
     6661 actcgtgctt tcggttgacc gcgatgaaga tatcaatagt ctcgccattc cgcccgctga
     6721 tgccatcgat cgtcagggac gtctggtact cattcagtat cggcccaaat gatctggcta
     6781 acattagtct ttgccagctt gcttagcgtt gccgggcagt tgtgtcagaa acaggcaacc
     6841 tgctttgcgg cggtaaacaa acggcgcaaa catatcgtgc tgtggctggg actggcgctg
     6901 gcttgtcttg gccttgccat ggtgctctgg ctgctggtct tgcagaacgt accggtaggc
     6961 attgcctacc cgatgttaag tctgaatttt gtctgggtaa cgctggctgc agtaaaactg
     7021 tggcacgagc cggtatcgct gcgtcactgg tgtggggtgg cgttcattat tggcggcatt
     7081 gtgatcctcg ggagtacggt gtaatgggcc tgatgtgggg attattcagc gtcattatcg
     7141 cctccgctgc gcaattaagc ttgggttttg cggcgagtca tctgccgcca atgacgcact
     7201 tatgggattt tatcgcggcg ctgttagctt ttggcctgga tgcccggata ttgttactcg
     7261 ggctgctggg ttatctgctt tccgtttttt gttggtataa aacactacat aaacttgcgc
     7321 taagcaaagc ctatgccttg ctcagtatga gttatgtgct ggtatggatt gcttcaatgg
     7381 tacttcccgg ctgggaaggg actttttcgc tgaaagcact actgggagta gcctgtatta
     7441 tgagcgggtt gatgctgatt ttcctgccca caacaaaaca acgttactga gttttccctg
     7501 ccgctttaca ctgccgttcc cactcatcgg ggctataaca gcttgcagaa agaactttca
     7561 ccgtgtgcag cttttcacga ttaatacagt aaagcgcatt ctgcaaaggc gagagtaaat
     7621 cccccacttt cacggcgaag tcactcttca cttcggcgat catttttatc gcgccgccag
     7681 catcgcagag cataagtaca tgtctgttat tttgtttatt gcagcacgat tttttgacca
     7741 gccattccat tgcattatcc tgtttgataa gagttttcac atcaatttac agattaacag
     7801 ataaacctat tatcaacggc aatggaatgg caaaattgcg aagtgaaact aatgatttct
     7861 taatcctggc gttgcaccca ctcttttaac gcctgacgtg aaattttaat accgccgttt
     7921 ttcagctccg gcggtaaagt cagccagcgc accggttgtt gaaaacgggc cagcttatct
     7981 ttcacccatt cgccaagatc aacggtttgc tggtcatact ccaccaccgc taccggtcga
     8041 tgaccaaact ccttgtcagc aacgggaacg ataaacacct gcaaaaccgc aggatgtgca
     8101 gcaataacgc gctcgacttc ttctggctga atgccttcgc caccactgaa gaacagattg
     8161 tctaaacgtc cgacaatggt cagcttgcca ttatgcatct caccgcgatc gcgcgtggcg
     8221 taccagcctt cgtcattaac cagtggaacc cgttgcccgt tacgccagta accttctgcc
     8281 atgctggcag cccgcagcca cacttcgtcg tttacgattt tcacttcccg acccggcagc
     8341 ggcgaaccga cgtctgccag accgtcggct tctttcgcac acaccgtgga ggcaaactcg
     8401 gtcagaccat agccgcaaaa gcaccgaatc ccctgctcgc gcgcctgttc cgtcaactcg
     8461 accgggatag ccgcgccgcc aagtaaaacc gctttcaggg aaacggaact acggttaacc
     8521 agcaaacgcc agagttgtgt tggcaccagt gaagcgtgcg tacagcctgc cagcatttgc
     8581 tccaatggct gtttatcacg taccgtcatc cgcgcaccag cgtataacca gcgccacata
     8641 attccctgac cggagacgtg aaacagcggt aaagagagca accagtcatc gtgatcgcca
     8701 aacggaatca gcgataacac cccttcggcg ctggcaagat gagcctgata agtatgaaca
     8761 gcggctttcg gcaagccagt ggaaccagag gttaacgtca ttgagcacag acgcgtcggc
     8821 tgccacgcca cggcatgtac gccttcaacc tgctgaatat gcagcgacgt taacgccgga
     8881 aacgtgtttt ccccttccgg caccagcgca aattgcagcg taagattggg cagcaattcc
     8941 tcaagcagcg gttgcggcag ctgagggttc acgggcaaca cccgcgcccc gcattgcagt
     9001 aacgccagcc aggccagcag cgtttgcggc gtattccacg cccgcaacat cacgccgctg
     9061 cccgcaacca caccctgcgc cgcaaagctg gaggctaatt catcgacgcg agcacaaagc
     9121 tcgcgccagt tgagttgctc gtcattaaga cgtaaggcga tggcttctcc ccgcacttgc
     9181 cgccagtgac gccacggcca gtcagagaag atcataacag ccgctccagt gcatcaacgt
     9241 ccactaacgg cagtggactc cccggccagc gacgaacctg ctgcacctgc atcagatcca
     9301 gcgtgtccag tcccggaatg gtgtctggcg ttaaccaggc agcaatccgc gccagttgca
     9361 ttagacctaa gctcgactca atggaagaac tgatcaccgc cgtcagcccc agcgcatgcg
     9421 ccgccttcac ctgctcgcgt actttctcca ggctgcccgt gagcgtgggt ttgataacta
     9481 ccgcgcgcac gccctcttca gctacaaagg caaaatccgg ctcgcgcaag ctttcatccc
     9541 aggcaatggc aatgccggtt tcacgggcaa acgcacgcga atcatcgcgg gttttgcacg
     9601 gctcttcgag aaatgcgatg cggtggcgat aatccgggtt aacgtatttg gcaaactgct
     9661 ggcctttcag cggtgtccag gcgcgattcg cgtcaagacg caaatgcaga tccggaattg
     9721 cctccagcaa cagattcacc accatgccgt cgcgcacggc ttcatacaat cccactttga
     9781 ccttcgccac tttctcgcca ggcatatcgg caagtttgag gatcagatcg tcaggatcgc
     9841 cattacacag cggtgccgca cggtaattgg ccgcctgcgg gagcgtatct gccagctccg
     9901 ccaatgcaca acttacgcca aaggcaacgg aaggcatctg cggtaattcg caatcgcctg
     9961 ccagccagtt atttacccag gcaagcagca cactttgcgc atcttcccag gtttcctgac
    10021 tgaagcccgg cagtggggag atctcccccc acccttcgcg ctcaccctca cgcaggcaaa
    10081 catacagccc gtcgcgggtt tttaaccgcc tgtcgcgcag aaccaccccc gcgtccatgg
    10141 ggatctgcca gcggtatacc tgcgcgctac gcattacgga ttccgtttaa atttgctgaa
    10201 atcaggctga cgtttctggt tgaaagcatt gcgaccttcc tgaccttctt ccgtcatgta
    10261 gaacagcatg gtagcgttgc ccgccagctc ctgcagcccc gcctgcccgt cacagtcggc
    10321 gttcagcgca gctttcaggc agcgcagcgc catcgggctg ttttgcagca tttcacggca
    10381 ccaacggacg gtttcttttt ccagatccgc cagcggtacc acggtgttta caaggcccat
    10441 atccagcgcc tgtttcgcgt cgtactgacg gcacaagaac cagatttcac gcgctttttt
    10501 ctgtccgacg atgcgagcca tgtaggaagc gccccagccg ccgtcgaagg aaccgacttt
    10561 cgggccagtc tggccgaaga tggcattatc agccgcgata gtcaggtcgc acatcatgtg
    10621 cagaacgtga ccgccgccga tggagtagcc agccaccatc gcgacaaccg gtttcggaca
    10681 ggtacggatc tgacgctgga agtccagcac gttcaggtga tgtacgccgg aatcatcttt
    10741 atagccgccg taatcgccac gcactttctg gtcaccaccg gagcagaacg ctttatcgcc
    10801 tgcaccagtc agaatgatca cgccgatgtt gtcgtcataa cgcgcatccg ccagcgcctg
    10861 gatcatctct tttaccgtca gaggacggaa ggcattgcgc acctgcggac gattaatggt
    10921 gatttttgcg ataccgtcgg tggatttttc ataacgaatg tcctcaaaac cttcggagca
    10981 gtcgtgccat tcaaccggtg cgtaaagcat tgcttcatca ggataaatca tattgtgtcc
    11041 tttagtcaga aacgcaagat ctgcgccaga cttgcgatta cgccagcggg attttcccgg
    11101 tgcgcgttat gtccggcgcg aggaatgaca tggcagtcgg cagccagttc cgccgccaga
    11161 gcgcggaatt tgctgtcacg ttcaccacat aaataataaa acgcaaatgt gcgggcgcta
    11221 aggttagcac gtaaatcggg ctggacggcg agagaagtcg cctccagcat ggcggcaagg
    11281 gttgcgccat tattgttgct gcgcagcgcc accagctccc ggcgttgatc gtcattgagc
    11341 gaggcaaaaa caggctgttg ataccaatcg gcaaataccg ccgttaacgg ttctgtacga
    11401 aaacgctgcg cccattggcg atcggaacgc tgacgttccg cgcgttgttc agcattttgc
    11461 aacccaggat gcccgccttc gacaacaact ccacaaagcc ccgccagctc ctggcaagcc
    11521 gccatcatcg ccacccgtcc gccaagcgag taccccacca gccagaagtt aaggatgttg
    11581 taactaacca gcgttttaca cagtaagtcg gtgacatcat caaatccatc gacgctgatc
    11641 gtcgctgaac caccgtgacc tgggagatca acatacaacc gcgagtagtc ggcaaacgcc
    11701 tcgcccactt cttgccattc atggcaatcg ccggaaaaac cgtgcaaaaa caccagccag
    11761 ggtaaacctg gtttgccgtg ttttgcctgc gcgtgcagga tcataaatgg cttacctgcg
    11821 ccagaagttg ctggagcgtt tgcgcaccat cggtgtcgtt aaccaccatt tcaatcaccg
    11881 tggtggtcgg cgtacgccag gcatcgacta gtgtcgtttc aagttcctgc cagttttgcg
    11941 gacgatgata tttcagctcg aacatcgcgg cggcgtgctc aaaatggacg ttttgcggca
    12001 tcagatagaa acgcccgcgc tcgcttttcg gcgttggcaa cagcgaaaaa atttgcccgc
    12061 cgttgttgtt caccacaatt aataccagcg gtgcggaaac ctggcgcaat aacgccagcg
    12121 cgttgagatc gtaaagtgcg gagagatcgc ccacaatcgc cagcgtcggt ttgccgcttg
    12181 cccgctgaac gccggcggca gtcgagagca gcccgtcgat accgctggca ccacggttgc
    12241 tgtacaccgg gtaacctgcc ggaagttgcg aaagcgcatc aatcagacgc accaccaggc
    12301 tgttaccgac aaacaattgc ccctgttcag gcaaatagtc gctgatgcga tgcgccagtt
    12361 gcgcttcgcc aaacgcatcg cgacgggcaa taaccgcctg cattgcctgt tccgccaggc
    12421 gcgggatttc aacgcaccag ggctggcgtt tttctgccgg atgcagctcc agccagtcgg
    12481 caatattggc aattaagcga cgtccgcgat ggtgtgccgg atcaagtcgc ccttcaatgt
    12541 catcaacaat ccagtactct tctggttcac agcttgcctg ccattggagg agtcgtttcc
    12601 ccgtcaggct gcttcccaat tgcaccacta tttgtgcctg ttgcagttcg ctggtcgctt
    12661 tggcattgcc taaccagaga tcggcacacg gcagcggctg tccggtttgc gacagcacgt
    12721 cgccaatcag cggccagcca agagtttgcg cccacagtgc aacttttttg ccctcttccg
    12781 cactcatgcg cccggcaacc accacaccgc gcttttgtcg ccagaagaac cagtcgcgct
    12841 gtttttcact ttcccgacga ggcgcttcac gcagccacgg tttgtcgtcc tgccaccagt
    12901 cgcccagccg ctgttgccag ctaatccccg tgtcgtccat ttcgccatac agcggttcag
    12961 caaacgggca gttgatatgg actccaccag catgaagcgt accgagagcg tggtcgatgg
    13021 tagaaaccag ccaacgtgcg gggatatcct gggtcgggcg cggcagtgaa atactgtgcg
    13081 tggggtgaga ggcgaacatt cccggctgac gaatcgcctg attcgcgccg cagtcaatca
    13141 gctccggcgg gcgatcggcg gttaacagga tcagtttttc tccggttaac ccagcttcaa
    13201 tcagcgccgg atagagattt gctaccgccg tgccggaggt cacaatcacc gccaccggct
    13261 gcttgctgac tttcgccagc cccagcgcca gatgccccag tccacgctca tcgaaatggg
    13321 tgtggtgaat gaatgcggaa ttctccgccg ccgctaacgt taacggtgta gaacgcgagc
    13381 caggggcgat acagatgtgt ctgacgccgt gacgcgttaa tgcttccaga atgaccgccg
    13441 cccagcgtcg gttaaatgcg cttactgaca tgagtttgtc cggtatcaat attgcggcta
    13501 agtataagga gctacaaaaa tagattattg atatgaatcg gtaatgatgc gactcattac
    13561 tattccattt gtaataaagt acgcagccct gccgctttgt tgtcgatttc ctgccactct
    13621 tgctcggggt cggaaccacg gacaatgcct gcgccagcat atagccgcac gatattgccg
    13681 ctgatttttg ctgagcgcag ggaaacgcag aattcacttt gctgtaatga aagatagccc
    13741 gcagaaccgg cgtaccattc tcgagtgaac ggttcgtgac gggcgataaa ctgtcgcgcc
    13801 agatcgcgcg gtaagccagc aactgctgcc gttggctgca actgatgtaa acagatcaca
    13861 tcatccgctt tgttgagtga agtccagata cagcggcgaa gatgctgtac tttacgtaga
    13921 cgcagtacct gcggcggtaa aacatccagc gtccgggtat cggcctgcaa tcgttggcag
    13981 atatcttcca ccaccaacat gttctcgcgc tggtttttat catccgccat cagccactca
    14041 cctaactgct gcgcctgctt atcatcagga tgatttgcta ccgttcccgc cagcgcttcg
    14101 gtacgcagcg ctttgtcacg ccgccgccat aaccgttccg gtgaagaacc aagaaaagca
    14161 ttttcgccat caaaggccat gtaaaaatgg tagcaattca gattgagccg acgactggca
    14221 gccatcatcg ctgccgcatt gaccggactt gcgaaatgca ggtcagttgc ccgagcaagc
    14281 acaactttgt cgagctcgcc ttcggcgatg gttttcgttg ccagttcgat taatagcgtc
    14341 cagcccgttt tgtccggcca gtgttgttct cgcgtggtgg ttaaatgtaa tccaggcagg
    14401 ggcttgatac tcaccagtgt ggcgataaat tcttttgcct tgattgcatc gtgctgaagg
    14461 gagctttcgc tgaatagcgt caaccgcagc gtggctttac cgccacaacg tcgccattcc
    14521 aggcgtggta aaagtaaata gccctgcgac gggtcaaacg cattcaaccc ccagatgcgt
    14581 aagtcggcgt gttccgggtg ctggcgaaga aaacgttgtg cctggtccaa cgacgtaaaa
    14641 cgggtaatcg cacccaggac ggcagcttct tcatcaccat tacgttgttg ccagtagaat
    14701 tgcggataca cctgctgact ggccagccag ctcaaggcat caaaagcgtc tttgagaggg
    14761 aaaggaatat cgataacccg aatgccgggt gtcgccggaa tctcttgcga caaatggcgc
    14821 agtagatttt ccagcgccgt agtaagtgat tgcacgcgga cctctccctg ttaaaagcct
    14881 cacattatac ggggtacgac aaaaaaaatg cagtaccccg gtgtagggag gttttaacgg
    14941 cgtgccagca acagtcctag aaccagccca acggccgcac ccacaccaat tccttgccag
    15001 ggtttttcgt ggacgtagtc atcagcacga taaactgcct gcttcgcccg atagtaataa
    15061 ctgtctgaag cctggctaac ccgttttttc acatcatcca gcgctttttc tgcacgcgct
    15121 ttcagctcaa catatttctg atcggcggga tcgccagagg agcggagcac ctcttccagt
    15181 gtttcactaa gcagcgtcag gtcgtcatca atacgtgtat caccaaactg attagacatt
    15241 ctcgttctcc atttgtgtaa aacctgtcac taactataga caagggttat tgattacgcc
    15301 tgaattacct cgcgtgccat cccaatgtgt gggataccat cttcttcata aatatcggtc
    15361 acagggatga aaccaaattg cccataaaag ttttgtaaat gcgcctgcgc ccccagataa
    15421 atcggcttct ccggccagcg gcgagtacac gattccagcg ccttactcat caattgctga
    15481 ccgatttttt caccgcgtaa ggcttcgctg acaatcaccc gaccaatcac aacgggttgc
    15541 agttcgtcgt cacttttcag aatcctcgca tacgccacca gtgtcccgtt atgccaaccg
    15601 agaatgtggc gattttctcc ctccagatcg tcaccatcga tatcctggta aggacagttt
    15661 tgttccacta caaataccgc acaacgcagt tgtaataagg cataaagctg agaaacggat
    15721 aaatcagaat gatgcagatc ttgccagtcg atcatggaag gctcctttgt gctgtttgct
    15781 ttatactagc cggaatattt tcagcagcgt gatgaactca tggaattaat ttttttaggt
    15841 acttcagccg gtgtgccaac ccgtacgcgt aatgtcacgg caatattgct taacctgcaa
    15901 catccgaccc agagcggact ttggttattt gactgcggtg aaggcaccca gcatcagcta
    15961 ctgcatactg cctttaaccc tggaaaactg gacaagattt ttatcagtca ccttcatggc
    16021 gatcatctct ttggtttacc cggcttgctg tgcagtcgtt ctatgtcagg cattatccaa
    16081 cccttaacga tttatggtcc gcacggtatc cgtgaatttg tggagaccgc gctgcggatt
    16141 agcggctcat ggaccgatta tccgctggaa attgtcgaaa ttagcactgg cgaaattttc
    16201 gatgatggcc tgcgcaaagt gaccgcttat ccgatggaac acccactgga atgttatggt
    16261 tatcgtattg aagaacatga taaaccaggt gcattaaatg cccaggcatt aaaagctgct
    16321 ggcgtgccgc ctggcccgct gtttcaggaa ttaaaagcgg gcaaaacaat catgctggat
    16381 gatggaaggc agattaatgg cgcagattac ttagccgctc cagtgccggg taaagcgctc
    16441 gctattttcg gcgataccgg cccctgcgat gccgcgctgg agcttgctaa aggcgtcgac
    16501 gtaatggttc acgaagcgac tctggatatg gcgatggagg ccaaagccaa cagtcgcggc
    16561 catagttcta cacgccaggc ggcggcacta gcccgtgagg ctggagtcgg taagctaatc
    16621 attacccacg tcagctcacg ctatgatgac aaaggttgtc agcacctgtt acgtgaatgt
    16681 cggtcaattt tcccggcgac tgaactggcg aatgatttcg cggtgtttag catttaagtc
    16741 gaaagcggtg gttagttagc agattaattt aacgatacca acacatttat ttgacatttt
    16801 ttcatctgtt tgccggatac gtttgatgtc gatatcaggc aaacagaatt atcattttta
    16861 gttttgtgaa ttgtccagat ctttcgccag tccaatcagg cgaataaatt ccgctctgta
    16921 accctgtgga tcttcccctt ttgccttctg agcccactgt ttgatctgct gccaggaggt
    16981 attgttcagg tattcagaac cgcgtaactt ttgcccatat gcagccactg ctgcgcgaaa
    17041 gcgcatatct tctgaaggtg cctttattgc agatgccaac gggaattcaa ctaactgact
    17101 ttcttttccc tgtggggatt tccaacgaat ctttaaccag gcaagttctt ttgttttgtc
    17161 cgatttcgct gatttgttat ccggggcata gcgtaactta tcaattgatg ctttttgccc
    17221 tttcagcgtt aattcaaata acaatgttat atgtttacct gcgccaatat cacccgcatc
    17281 aacgttgtcg ttattaaaat cctctgcctt aagttggcgc ttttcataac ctatctgacg
    17341 gtattccgtt acccacgcgg gattaaactc aatttgcgct ttgacatctt ttgctacggt
    17401 aatcaacgtc tgccgcattt cactgttcaa cactttctgc gcctctgaga gggtatcaat
    17461 gtagctatag ttgccgttac caacatcggc aattctcacc atcattgcct cgttataatt
    17521 gctatccccc acgccaagcg tcgacagagt aacaccggac tcacgctgtt ttttgaccat
    17581 tgattcaatc gattttggat cgtcaatgcc aacgttaaag tcaccgtcag tggccaataa
    17641 aatgcgattg ataccacctt taataaaccc cttcgctgcc tgctgataag ccatctccag
    17701 cccggcaccg ccattggtac tgccttctgc atccagcgaa tcaattgcag cattaatttc
    17761 cgccttgtga ctaccggaga tagaaggcaa cgcaatacga gagtcgccag cgtaggtcac
    17821 gatggcaatg ttatcctgct cacgaagttc tttgaccaat aatttcaacg aagactggat
    17881 aagtggcaaa cgttcatcag aaatcattga accagacgtg tcgataagaa agaccagatt
    17941 agaagcgggt aactcttcac ttttgcgatc tttcgccagg atatcaactt tcagcaatgt
    18001 tcgctgttca ttccagggtg caggtgccaa ttcgtagcgc atagcgaaag gtattggctt
    18061 agaggccgga atagattgtt tgtctttgat atcccagtca gacgggaaat aattgactat
    18121 ctcctccacc cgcacagcgt ctggcggagg taacagccct tgattaagga aacgccgcac
    18181 attcgcataa ctgccggtat cgacgtcaag gctaaacgtc gccaacgggt tttgcgctac
    18241 ctgcttaacc ggattatcat cgaactgctg gtagcgagcg gttgctggat ttgcgatttg
    18301 ggaggctgct ttttctctgg ctgcatgttg atattttgga gccgcctgca atcgccccag
    18361 caaagcctgt ttgtctgaat attgttgcac ttcttgctgg gctaaggctt tcgcgtctgc
    18421 agcggctttg gcggcgcttt gctcagccac ttttgttgcc gcttgttgcg cggcaagcac
    18481 ttgctggtca gtgggtgtag tagattgttg ttgctgactt ttcttatcct caggttccgg
    18541 cccacatcct gacaaaatca aactacttat aagcaacatg attatatttt tatttcgcat
    18601 ataaaatcct tttaaataaa ctcagggccc cga
//
LOCUS       DAFGPF010000094        18554 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFGPF010000094 DAFGPF010000000
VERSION     DAFGPF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18554
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.094"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..310)
                     /locus_tag="LSX49_003685"
     CDS             complement(<1..310)
                     /locus_tag="LSX49_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HBL7170045.1"
                     /translation="MTSQSVLPPNAITPERALEVVLSHVGDLPGDIRIIKNPDLCPAN
                     LLPWLAWEYAVTYWNPDWSEQQKREIIKAAAWQNKHRGTRGAVERALLTVGFESKMRE
                     W"
     gene            complement(313..1233)
                     /locus_tag="LSX49_003686"
     CDS             complement(313..1233)
                     /locus_tag="LSX49_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001729001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBL7170046.1"
                     /translation="MITSTVQNSIVKTIDMSLLPPPAFVKTPLFSDVKSNLLSELQIL
                     YPQFNALLESDPAVKLLEIVAYREIIITARVNQGMLAVLLAFAKGSDLDQIGANFDCL
                     RLLITPANPDVIPPTEAVYESDDEYRHRIQLSWYARNTAGSTNAYNYFALSSDPDVLS
                     AQAYGPPVTQPGYVDMYVLSRTGDGTPPQSLLNTVNAALSPDDTRPLTDFVTVKPASN
                     LNYRVEAVIVAGLGPDQNVLLNGAQSDLAIYVDTQHKIGATAALSGIYDAIHRDGTER
                     VILISPTEDVIAGVGQAPYCTEIKLSVQMG"
     gene            complement(1230..1571)
                     /locus_tag="LSX49_003687"
     CDS             complement(1230..1571)
                     /locus_tag="LSX49_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HBL7170047.1"
                     /translation="MLGMDRNTGKLLSGTDHIRQSIVDILTTPLGTRVMLPEYGSKLF
                     DLVDNPTDPSLAMRIIMESAGAIARWEPRVRIDRINVLAVDIGKITILIIATDIETQQ
                     RLEFNNMELIF"
     gene            complement(1574..2476)
                     /locus_tag="LSX49_003688"
     CDS             complement(1574..2476)
                     /locus_tag="LSX49_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HBL7170048.1"
                     /translation="MAQSDDEYAAAENARRLRDAVKRGTIAAVKMNPPRCRVSFGGEH
                     QSGWLQWFTHATSERVDWSAPSVGDPVTVVSEGGDTRNGVVMLGLHIDDKAPPSNDPH
                     DHVTAYCDGATMTYNTKNHTLTWQGVPDGVVKILGESEIEIFGRADVTINSENVVNIH
                     GGKLINADADIINVTATDTINAHADLVNVIATSSVSVTAANRISLTAQTISAWAPGGI
                     TLAGPTHITETLVVDKLATFRNDISVTGDNGGTGNITTRGSVLAGQEVQDRQGTITEV
                     RTTYNGHTHICPDGETQQPNQPMA"
     gene            complement(2457..2993)
                     /locus_tag="LSX49_003689"
     CDS             complement(2457..2993)
                     /locus_tag="LSX49_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170049.1"
                     /translation="MSGLDAFDEYLDRVKGAVLQIPFIKTFGIYPEIPAGFETPALFL
                     EISNWSQSDESVPGSIQSVELSCNLYLLREFAADQYGLKSQNAALYMTSWINGRMFGP
                     GTKPAKFSDAEPCDWIKNGQSVGSHSVQCVSFTQVVGVGPDIFDYPSQGTLKNIYVGI
                     APDIGAEHEGDYYGPIGR"
     gene            complement(2990..3670)
                     /locus_tag="LSX49_003690"
     CDS             complement(2990..3670)
                     /locus_tag="LSX49_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170050.1"
                     /translation="MADLRSNAQMFDIDVSALEQLRVEISATQHQMLMVYNRALNRTA
                     KHMHRISAGMILTALAAKNHKAVDKRIKPFIKRRNFTKEGAGDLSSAKLWYGLNDFRV
                     SELKGRLQNPRRQKQPRDLETGLFLKTKKGARGATFTPKSAGLAMMSWPDSFVAKRYG
                     AKSVWIRLDRGGIEEARVPVHDALEDAIDDYIFENIGPVFMGFFEKDLRGRVKGNVHV
                     DPKTGKRL"
     gene            complement(3702..4082)
                     /locus_tag="LSX49_003691"
     CDS             complement(3702..4082)
                     /locus_tag="LSX49_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170051.1"
                     /translation="MSYYDDLRAGDEEMIREWGRPVKLRGKTDPIIAIFNEPYARVDV
                     PHAGFITGTVTSLTALSDDVAGVVARDVVQVPKQRSIEPDGSVTWSGWTDYVVKEPQP
                     DGTGLTNIFLEPHTSSENSEYSKY"
     gene            complement(4079..4498)
                     /locus_tag="LSX49_003692"
     CDS             complement(4079..4498)
                     /locus_tag="LSX49_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HBL7170052.1"
                     /translation="MSTKTELLARIDDLSAQLGRELPRSGTIAELESIVAGAESELDI
                     LNEQSGDAGGIEITVNTASGTDNELAQSIASAIVSQSQEQELAPATRRVKLRNTLDVY
                     HYVNGRRVREIVAAGREIVVDSPEVADLIAADHVYAL"
     gene            complement(4533..5567)
                     /locus_tag="LSX49_003693"
     CDS             complement(4533..5567)
                     /locus_tag="LSX49_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HBL7170053.1"
                     /translation="MSDSFTTSELITATQQVFKFNPLFLKLFFRETYTFTSEEVFLDK
                     IPGKVNMAVYCAPMITGKVDRTRGYSTNHFKPGYTKPKHTINPNMSIKRAAGEQIGQP
                     ETPVERRAKIIMQNLLDEELSISQLEEFQAVQAVLYGKYTVSGSNIETYEIDMSRSAT
                     NNVTQSGSTAWSTQDAETYDPSDDIESYADLASGAVNVIIMDGKAWKQLKRFKKFWTA
                     LDTRRGSNSQLEVALKNLGDVVSFKGYYGDTALFVYKGQYLDPVTDTETRYMPDNTMI
                     LGNTKNRGLRTYGAIQDEDALKEGISEATRYPKVWTTTGDPAVTQTMTQSAPAMVLTD
                     ADAFVVVKIA"
     gene            complement(5626..5955)
                     /locus_tag="LSX49_003694"
     CDS             complement(5626..5955)
                     /locus_tag="LSX49_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HBL7170054.1"
                     /translation="MTTETYSPDDFILGPDLVVTTVGHFQGGINVPRLTPIMLDATVG
                     TFKVWDGSVGKAIGLTATAVNTGSSSADCSYYKSGSFRYTAINWGTVTDVAKRKSAFA
                     GTPISVG"
     gene            complement(5955..7262)
                     /locus_tag="LSX49_003695"
     CDS             complement(5955..7262)
                     /locus_tag="LSX49_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HBL7170055.1"
                     /translation="MPWNNFPHLAARAFNQPLLLEPTYARVFFSALSDRFGTGRLIDT
                     ASGEVMNSDEMNALAMGWDSSERTRQKSYRVERGIAVLPVTGTLVHKLGYINPVSGMS
                     GYNGIAKRLQQAISDPDVRGVLLDIDSPGGEVAGAFDTADLIARAREQKPVWALASDT
                     ACSAAYLLASACSRRLITQTGTVGSIGVLMAHRCVEKALEIAGVDVTLIYAGAHKVDG
                     NPYSQLPGDVRDEFQLSINSTREQFAQKVSDYTGLKKSRVLATEAAVFIGADAIKSGL
                     ADQLVNYADAIAVMADALKPKMERFMSGTETTAETTTTEQTATTTTVAQVEFNTEQIR
                     ADAASSELARVMAIINCPEAVGREAQAKALAGVPGMTVGQAQVVLAAAPKTAQARTET
                     ALDTLMSTESPATIQDAGSTTATGTTANVSMLVAAGRSILGDE"
     gene            complement(7262..8836)
                     /locus_tag="LSX49_003696"
     CDS             complement(7262..8836)
                     /locus_tag="LSX49_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL7170056.1"
                     /translation="MTAPQQLLGPDGKTPLRRYAGYNGGGPGFGGQLIDWNAPQQSAD
                     AALLPNFYRGNARADDLVRNNGVASNAVQLHQDHIVGNLFKLSYRPNWRYLGISREDA
                     RALARDVEVAWTEYAEDPHCTIDIERKRTFTMMIREGVATHAFNGETCVQPVWESSAG
                     SVFRTRFKMVSPKRIRNPGYAADTQFRRAGVDIDKNGAAVGYWIAEDTYPLGGVGKCR
                     RIPAQLSSGRHAFIHIFEPLEDGQTRGDNIFYSVMERLKMLDTLQQTQLQSAIVKAMY
                     AATIESELDSQQAFEYIAGAGTDIDSNPLNSFIQSYVTYYNGANIKLGGVKVPHLHPG
                     DKLSLQTAQNADAGFSSLEKSLLRYVAAGVGASYEELSRDYSQVSYSSARASANVSWR
                     FFMGRRRFIAARQASLMFCCWFEEALARGIITLPRSAVRSFYEARNSWTNALWIGAGR
                     MAIDGLKEVQESAMRITTGLSTYQNELALQGQDYEEVMEQQEYEIQRRREMGLSEPSW
                     SVSHPSNTNDNGWGGN"
     gene            complement(8833..9066)
                     /locus_tag="LSX49_003697"
     CDS             complement(8833..9066)
                     /locus_tag="LSX49_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170057.1"
                     /translation="MTSREVLTERLLEAEIALHKLLTGKSTVSLSHGDSAGNNRSYQY
                     SQASIEQLRTYIIELKSQLGLSTGRRRPVGVRL"
     gene            complement(9066..10928)
                     /locus_tag="LSX49_003698"
     CDS             complement(9066..10928)
                     /locus_tag="LSX49_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HBL7170058.1"
                     /translation="MTGVEWADKYFYLPEGSSHIAGHWTTQPVQVVMLNMMTNDAIKI
                     VSVRKSARLGYTKILVAALLYFAEHKKRSAVVYQPIDDESDGFVADEVDPAIAEMPVI
                     QKIFPDWDKSNERNNLQRKEMSGAILDFRGASAPGNFRRLTKQVVEGDEVDGWPLEVA
                     KKGKGEGSPIELALVRIKGAAYPKAIFGSTPTVTGKSHIEMLEDAADLTFRFYLTCPH
                     CGEEQVLVFGFDGIEYGLKWDNSLQTNEAKSSSAYYQCCHCPEHFYYRDLEKMEFGGR
                     WIAEDCTWTRDGIHFFDHDGGVVRAPKHAAIVINALYSLNLDGWGEIVSEWLKAKGDP
                     LKEKTFHNTTLGELWSDVASEQLEHDILVNRREKYASQVPDGVVYITGGIDSQTSGRY
                     ECYVWGWGAEEECWLIDKTIVLGRYDEEDTLQRVDGVIRKQYRRSDGTTIGVSRWAWD
                     TGGIDAQVVYNRSLKLGPLWVIPIKGASSYGQPVVNMPRTRNANKVYLSLIGTDTAKD
                     LLAMRLQLEPDSKSATPGAIHFPNDDEIFSTTEAKQLVSEVLIPKLINGRVVYRWDNQ
                     GRRNEALDCWVYGLAALRISKIRFQLNLETLAEQRKKSQNKLSLEEMARMLGGS"
     gene            complement(10915..11481)
                     /locus_tag="LSX49_003699"
     CDS             complement(10915..11481)
                     /locus_tag="LSX49_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170059.1"
                     /translation="MASQAEVAAHLLLSDRRLRDLAKLPGAPVPQGRGDWELDAWRHF
                     YIRYLRSNRRDTTSNDEPEAGDNSPEKNREQWLKNEERQERILMARVKRRILAKRYAP
                     IELISVAVSRVAVELRTRVESWPPRLKKVWPEMPQEASSVLREELAIALNELSDIRID
                     FSDYDVSDIERDLDRVESLARDDTDDGC"
     gene            11850..12095
                     /locus_tag="LSX49_003700"
     CDS             11850..12095
                     /locus_tag="LSX49_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170060.1"
                     /translation="MNREKIEALMSVILKEADPKKFPEKLSEDAIVSFYRANSSYLNC
                     STLREWLSGEAEPSDEILQKIMVQNNWRATKWSNQLP"
     gene            complement(12155..12349)
                     /locus_tag="LSX49_003701"
     CDS             complement(12155..12349)
                     /locus_tag="LSX49_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001727234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170061.1"
                     /translation="MKKLLLAVAFFTLAGCTHSTYTEATRADGSSIKHVMIAPGTKIT
                     TANGGCIDSTGAEASCLGGK"
     gene            complement(12357..12836)
                     /locus_tag="LSX49_003702"
     CDS             complement(12357..12836)
                     /locus_tag="LSX49_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02594 family protein"
                     /protein_id="HBL7170062.1"
                     /translation="MTDPKWLIEARKNLGIREMKGKQHAAEIVQYWKDIKRGGIKDDE
                     TPWCAAFTGAMLERAGIRSTRFESANSYLDWGNELKEPAYGCIAILSRSGGGHVGFVV
                     GKNAAGDLMILGGNQADEVNIKAFPRSRVTGYRWPAGQTDVPQSLPLVNAEKSISEA"
     gene            complement(12836..13108)
                     /locus_tag="LSX49_003703"
     CDS             complement(12836..13108)
                     /locus_tag="LSX49_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000172496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL7170063.1"
                     /translation="MTLHSVLINANAIICLMLALRLMFFQKTGRYRFFISLTAYLAIL
                     SAAWIALRIFYGKYTQVDPAEFFLNLTICIAVWRARGNISKITGDR"
     gene            complement(13108..13491)
                     /locus_tag="LSX49_003704"
     CDS             complement(13108..13491)
                     /locus_tag="LSX49_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170064.1"
                     /translation="MSEPLTAGVAAGSAGVTFAALFPEATPAVMICALAGAALYVLSS
                     GQHRFWKQVIFALISFVGGVYCAETASAIITGILNAVLSHLNPPVTVKVSPAIGALVA
                     SVISVTSLLRIMSQARLWKSDKGMK"
     gene            complement(13604..14275)
                     /locus_tag="LSX49_003705"
     CDS             complement(13604..14275)
                     /locus_tag="LSX49_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HBL7170065.1"
                     /translation="MSNEYLLEYTRIKLRAALRDLSGGSKGQLEALCEHPPADKNAYP
                     RKHIHRVQLEDRTVDALVTPVYALESFSRRRPAPPMSDFEFADSSWRRSVNSLDASQQ
                     AWLRYCYGGNLAFKHQTAICEAVWSRYKGNIPASTQRKVVKRLLSLVWLSVQAVAAAN
                     KREDFKEMAGSTLAGMLSVSRSTWCETYSLHWVGMKEAVRALDEVALLATLHHYQNHL
                     DDVCV"
     gene            complement(14275..14568)
                     /locus_tag="LSX49_003706"
     CDS             complement(14275..14568)
                     /locus_tag="LSX49_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HBL7170066.1"
                     /translation="MKKIDLRKAARSRACTVRIPGVCNHNPETSVLAHYRLAGTCGTA
                     IKPHDMQGAIACSACHDAIDGRTKTDYEHDSLLLMHAEGVFRTLAIWRDEEFI"
     gene            complement(14565..15161)
                     /locus_tag="LSX49_003707"
     CDS             complement(14565..15161)
                     /locus_tag="LSX49_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1367 family protein"
                     /protein_id="HBL7170067.1"
                     /translation="MAQHSFIRVSGGSLIPATPDTQRWLTERVKPGAVVYADFKQARN
                     PAFHRKFFSLLNLGFDYWHPSGGAISPAERELVHGYVKLLAYYGGHGDVMAELADQYL
                     LDESEKRAGSISAVKSFEAFRAWAIMEAGFYDVHQMPDGSLMRVPRSISFAAMDDLEF
                     GQLYSAVLDVLWNYILFRTFASQEAAENAAAQLLDYTS"
     gene            complement(15239..15418)
                     /locus_tag="LSX49_003708"
     CDS             complement(15239..15418)
                     /locus_tag="LSX49_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170068.1"
                     /translation="MNIQESIGELPETCRAVIKRKDGHIVGVRVLTDDERIASLMAFL
                     ELAEIAGYTITPPDA"
     gene            complement(15570..16211)
                     /locus_tag="LSX49_003709"
     CDS             complement(15570..16211)
                     /locus_tag="LSX49_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170069.1"
                     /translation="MKTFYEDWPETFVSRLDMLRALDDRGSTRRLYLERTGAIFDALA
                     EEIRTVVAGHPEIDVSELDIGPLYRYYKRGEKGNPLADLLIELAPPTCERVRISPEVY
                     IIPYLFFALLIAQGADNDARDFFNMMMRPLIIAYRFKQLARYLGTKGGGRPQHRLKSE
                     AIELADRFFTENPTAPLSRGVQYISGIFVAKYSDPPAASTIRKWLIPIYRSDK"
     gene            16455..16688
                     /locus_tag="LSX49_003710"
     CDS             16455..16688
                     /locus_tag="LSX49_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170070.1"
                     /translation="MGTLGNQPCRSRYEFDDFNLANRAAALTKLAKETGVSVDTLIKL
                     EIAMQLNRLNSILIENGDKMDENLAGIGEILQK"
     gene            17087..17575
                     /locus_tag="LSX49_003711"
     CDS             17087..17575
                     /locus_tag="LSX49_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL7170071.1"
                     /translation="MATNPREHARRVLDTFWCGRGFPVDPAKIAHDMGLDVFITDLPG
                     KVSGALIKQKDQDPAIFLNSDDNKVRQRFSCGHELGHYIARQASHSDEYEYVDLRGET
                     ASAGTHPDEIFANKFAAELLMPVDEVRKLHADGQPSYIMAHYFGVSDDAMTYRLKNLR
                     LG"
     gene            17585..18190
                     /locus_tag="LSX49_003712"
     CDS             17585..18190
                     /locus_tag="LSX49_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170072.1"
                     /translation="MPSDDDFNSRFKQEVARRLKDSLNLHRQLAEEVEPEDDETPVQS
                     PDEASPQPKVSHAPKKTAVRIRGIARKRAAEARKMAVAASSKRIPTATPSQQVTRTES
                     KILTEFTSVKQVNSLDTEHERKQLNNKDFEAEIALKKRYGKWFLIILAFQLLIMNGVF
                     IADGAGKLEFEDLTLQLYMGGTLTEVFGLVLVVTKYLFKRK"
BASE COUNT         4500 a         4894 c         4427 g         4733 t
ORIGIN      
        1 accactctct cattttgctc tcaaagccaa cagttaataa cgctcgttca acagctccac
       61 gcgttccgcg gtgcttattc tgccacgcag ctgctttaat aatttcgcgt ttttgctgct
      121 cactccagtc ggggttccag taggtgaccg cgtactccca cgccagccac ggcaacagat
      181 ttgcagggca caaatcggga tttttaataa ttcgaatatc gccaggcaga tcgccgacgt
      241 gagataaaac aacctcaagc gccctctcag gggttattgc gttcggaggc agtacgcttt
      301 gacttgtcat ggctacccca tttgcacgct gagtttgatt tctgtgcagt acggagcctg
      361 cccgacgcca gcgatcacat cctctgttgg cgatatcaga atcacacgtt cagtgccgtc
      421 acgatgtatc gcgtcgtaaa ttcctgacag agctgccgtc gctccgattt tatgttgcgt
      481 atccacatat atcgccaaat cgctctgagc accgttaagc aaaacgttct ggtcgggtcc
      541 gagcccggct acgataacgg cctcaacccg gtaattcagg ttcgacgcag gttttacagt
      601 cacgaaatca gtcagcggtc gagtatcgtc aggagacagg gccgcattca ctgtattcag
      661 tagtgattga ggcggagtgc cgtcgccggt tcgcgacaag acatacatat cgacgtatcc
      721 aggctgggtc accggcgggc cgtacgcctg agctgacaga acgtcgggat cactcgacag
      781 cgcgaaatag ttataggcgt tcgtactgcc ggcagtattc cgcgcatacc atgatagctg
      841 tattcggtgt cgatactcgt cgtcactctc gtaaacagcc tcagtcgggg gaattacatc
      901 gggattagct ggcgttatca acagccgcag gcagtcaaaa ttagcgccaa tctggtcgag
      961 gtcactcccc tttgcaaacg cgagcaatac agcgagcatc ccctgattta cccgagctgt
     1021 aataatgatt tctctgtatg caactatttc cagcagttta acggccgggt ctgactccag
     1081 gagtgcgtta aattgtggat ataatatctg cagctctgac agtagattag atttaacatc
     1141 tgaaaataac ggggttttaa cgaatgctgg cggcggcagc agactcatat caatagtttt
     1201 cactatcgaa ttctgaactg ttgatgttat caaaatatca gctccatatt attaaactct
     1261 aatcgctgtt gtgtttcgat atctgttgcg ataattaata ttgttatttt cccgatatcc
     1321 actgctaaca catttattct gtcaattctg acgcgtggtt cccatcgtgc tattgcgcca
     1381 gcgctttcca tgattattcg catagcaagc gacggatctg tgggattatc aacaagatca
     1441 aataatttgc tgccatattc cggcagcatt acacgcgtcc ccagcggggt cgttaaaata
     1501 tcaacgatag actgacgaat gtgatcagtc cccgataaaa gtttaccggt gttacggtcc
     1561 attccaagca tctttacgcc attggttggt tcggttgttg agtttccccg tccggacata
     1621 tatgagtgtg tccgttatac gttgtgcgga cttcagttat tgtgccttgt cggtcctgca
     1681 cctcttgccc tgctaacaca ctaccgcgag ttgtgatatt acctgttcca ccgttatctc
     1741 cagtgacaga aatatcgtta cggaatgtcg ctaatttatc tactactaat gtctcggtaa
     1801 tatgcgttgg accagctagt gttataccac ccggagccca cgcgctgatt gtttgagctg
     1861 tcagcgatat tctgttcgca gcagtaacac taacagaact cgttgctata acgttcacta
     1921 aatcagcatg tgcgttaatt gtatctgtcg ctgtgacatt aataatatca gcgtctgcgt
     1981 taattaattt cccaccatgg atattaacta cattttcgct attaatagta acatctgcgc
     2041 gtccaaatat ttctatttca gactcaccga gtatttttac cacgccgtcc ggtacgccct
     2101 gccatgtcag agtgtgattt tttgtgttat acgtcatcgt agccccgtca cagtatgcag
     2161 tgacatgatc atgggggtca ttgcttggcg gagctttgtc gtcaatgtgc agcccgagca
     2221 taactacacc gttccgcgta tccccaccct cagaaacaac agtaacggga tcgcccactg
     2281 atggtgcgct ccagtcgacg cgttctgagg tggcgtgagt aaaccactgc agccagcctg
     2341 actggtgttc gccaccaaat gagactcggc agcgtggagg attcatttta actgcagcta
     2401 tcgtgccgcg tttaactgcg tcacgcagcc tgcgcgcgtt ctccgctgca gcatattcat
     2461 cgtccgattg ggccataata gtcgccctca tgttctgcgc cgatatctgg tgctattccg
     2521 acgtatatat ttttcagggt cccctgtgag ggataatcga aaatatctgg accaacgcct
     2581 acaacctgcg tgaacgacac gcactgaact gaatgcgaac cgactgactg cccgttttta
     2641 atccagtcgc acggttccgc gtcgctgaat tttgccggtt tagttccggg accgaacatt
     2701 cgcccattga tccagctcgt catatagagc gctgcattct gcgatttcag tccgtactga
     2761 tcagctgcaa attcacgcag caaatacaaa ttacacgaca gctcgactga ctgaattgag
     2821 cctggaaccg attcgtcact ctgtgaccag ttgctgattt ccaggaacag agctggcgtt
     2881 tcaaatccag ccggaatttc cggataaatt ccgaatgttt tgatgaacgg tatttgtaaa
     2941 accgcgcctt taacgcgatc aagatattcg tcaaatgcat ccagtccgct cataatcgtt
     3001 tacctgtttt tgggtctacg tggacattac ctttcacgcg accgcgcaaa tctttctcaa
     3061 aaaagcccat aaaaacaggg ccaatgtttt caaaaatata atcatcgata gcatcctcca
     3121 gcgcgtcgtg cacaggtacg cgagcctctt cgattcctcc gcgatccagt cgaatccaga
     3181 cacttttcgc accgtagcgt ttcgctacga atgaatcggg ccaactcatc atcgccagcc
     3241 ctgcactttt gggtgtaaaa gttgcccctc tagcgccttt tttggttttc aaaaacaggc
     3301 cggtctcaag atcgcgaggc tgtttttgcc tccgtggatt ttgtaatcgc ccctttagct
     3361 cagatacccg gaaatcattc agaccgtacc agagcttggc gctgctcagg tctcctgccc
     3421 cttcttttgt aaaattacgg cgcttaatga acggcttgat tcgtttatct acggccttat
     3481 gatttttagc tgccagtgca gtcaaaatca ttcctgctga aattcggtgc atatgttttg
     3541 cagttcggtt cagcgccctg ttgtatacca ttaacatttg atgttgcgtc gcgctgattt
     3601 cgactctgag ctgctccagc gccgaaacat cgatatcgaa catctgcgcg ttactacgta
     3661 aatcggccac ggttccccct taagtgggac cgaggtccca cttagtattt tgaatactcg
     3721 ctgttttcgc tggacgtgtg aggctctaaa aaaatattcg tgagccctgt gccatcaggt
     3781 tgaggctctt taaccacgta atcggtccag ccagaccagg taacagagcc gtcaggttcg
     3841 atgctgcgct gctttggaac ctggacgacg tcacgcgcaa caacgccagc gacgtcgtcc
     3901 gagagcgccg tcaggctcgt tactgtaccg gtaataaaac cagcgtgagg aacgtcaacg
     3961 cgcgcgtaag gctcgttgaa aatagcgata atggggtcgg ttttaccgcg taatttaacg
     4021 ggccgtcccc actcacggat catctcctcg tcgccggccc ggaggtcatc gtagtagctc
     4081 atagagcgta aacgtgatca gctgcgataa ggtctgcgac ctccggtgaa tcaacaacaa
     4141 tttcacggcc tgcggcaaca atctcgcgaa cgcgacgccc gttcacgtag tgataaacgt
     4201 ccagcgtgtt acgcaacttg acgcggcgcg tagccggtgc gagctcctgc tcttgtgact
     4261 gtgaaacgat agcgctcgcg attgattgag cgagttcatt atcggtcccg gacgcagtat
     4321 tcactgtaat ctcgatgcct cccgcgtcac cggattgctc gttcagaata tcgagctctg
     4381 actcagcgcc ggcaacgatt gattccagtt ccgcaatagt cccgctgcgc ggtaattcgc
     4441 gaccgagctg agcgctcaga tcgtcaatac gcgccagcaa ttctgttttt gtgctcatgt
     4501 tgattcctta acaaaaaaga gcctttcgac tcttacgcga tttttacgac aacgaacgcg
     4561 tcggcgtccg tgaggaccat tgctggcgcg gattgcgtca ttgtttgcgt cactgccgga
     4621 tcaccggtag tggtccagac ttttggatag cgcgtcgctt cggaaatacc ctctttcagc
     4681 gcgtcttcgt cctgaattgc gccataagtg cggagcccgc ggttttttgt gttgccaagg
     4741 atcatcgtgt tatccggcat ataacgcgtt tcagtgtctg ttaccgggtc gaggtattgc
     4801 cctttgtaga caaacagcgc agtgtcgccg tagtagcctt taaagctgac aacgtcgccc
     4861 aggtttttca gcgcgacctc gagctggctg tttgagccac ggcgcgtatc cagtgccgtc
     4921 cagaattttt taaaacgctt caactgcttc caggctttac catccatgat gatcacgtta
     4981 accgcaccgg aggcgaggtc cgcgtaggat tcaatatcgt cgctcgggtc atacgtttcc
     5041 gcgtcctgag tcgaccaggc tgtcgaaccg gactgagtga cgttattcgt cgcgctgcgg
     5101 ctcatgtcga tctcataggt ctcgatattg ctgccggaaa cagtgtattt accgtacaga
     5161 acagcctgta ccgcctggaa ctcttcgagc tggctgatgc tcagttcctc atcaagcagg
     5221 ttctgcatga tgatttttgc acgacgttcg accggcgttt ccggctggcc aatctgctca
     5281 ccggctgcgc gcttgatgct catattcgga ttgatcgtgt gcttgggttt cgtgtaaccc
     5341 ggtttgaaat ggttcgttga atagccgcga gtgcggtcaa ctttgccggt gatcatcggc
     5401 gcgcagtaca cggccatgtt cacttttccc gggattttat ccagaaaaac ctcttcgctc
     5461 gtaaacgtgt aggtctcacg gaaaaacagc tttaaaaaca acggattgaa cttaaatacc
     5521 tgctgtgtcg cggtaatcag ttctgacgta gtaaacgaat cgctcattta tatatcctgt
     5581 tataaaaaaa ccgcccggag gcggcttgtt ttgagttttt tgctatcagc cgacgctgat
     5641 cggcgtaccc gcaaatgctg atttgcgttt agctacgtcg gtaaccgtac cccagttaat
     5701 cgccgtgtaa cggaacgagc ctgatttata gtacgagcag tctgcagaac tggagccagt
     5761 attaactgcg gtggcagtga ggccaatagc tttaccgact gagccgtccc aaaccttaaa
     5821 cgtcccgaca gtagcgtcga gcataatcgg tgtcagccgg ggtacgttga tcccgccctg
     5881 aaaatgaccg acggtcgtga caacaaggtc aggcccaaga ataaaatcgt ccgggctata
     5941 cgtttctgta gtcattattc atcccctaaa attgaacgcc ctgcagcaac cagcatcgag
     6001 acgtttgcgg ttgttcctgt tgccgtagta ctgccagcat cctgaatagt cgctggtgat
     6061 tcagtgctca ttagtgtatc gagcgccgtt tctgtccgcg cctgcgccgt tttaggtgct
     6121 gcagcgagga ctacctgcgc ctgcccgacc gtcatcccgg ggacgccagc gagcgctttt
     6181 gcctgcgcct cgcgcccaac agcttcggga caattgatga tggccatcac acgcgccagt
     6241 tcgcttgatg cggcgtccgc gcgaatctgc tccgtgttaa actcaacctg cgcgacagta
     6301 gtcgtggtcg cggtttgttc tgtggtcgtg gtctccgccg tggtttctgt accagacata
     6361 aagcgctcca tttttggttt cagtgcgtcg gccatcactg cgatagcgtc cgcgtaatta
     6421 acgagttgat cagcgagacc agatttaatc gcgtccgcgc cgataaatac tgcagcttcc
     6481 gtggccagca ccctggattt tttcagcccg gtataatccg agactttttg cgcgaactgc
     6541 tcgcgcgtgc tgttaatact cagctggaat tcgtcgcgaa cgtcgcctgg cagctgggaa
     6601 tacgggttcc cgtcaacttt gtgcgcgccg gcgtaaatca gcgtcacgtc gacgccagca
     6661 atctccagcg ctttttcgac gcagcggtga gccatcagga caccgattga accaactgtg
     6721 cctgtctgcg ttatcagccg gcgcgaacac gctgacgcca gcaaataggc agcgctgcag
     6781 gccgtatcgc tggccagcgc ccacacaggt ttttgctctc gcgcccgggc gattaaatca
     6841 gcagtatcaa acgcgccggc gacttcaccg ccaggggagt caatatcaag caggacccct
     6901 cttacatcgg gatcagaaat cgcctgctgc aggcgttttg cgattccgtt gtaaccgctc
     6961 atcccgctaa ctgggttgat ataacccaat ttatgaacca gcgtcccggt aaccggcaga
     7021 acggctatac cacgctccac gcgatacgat ttctggcgtg ttcgctcgct gctgtcccac
     7081 cccatcgcga gcgcgttcat ttcgtcgctg ttcattacct ctccagacgc tgtatcaatc
     7141 agtcgcccgg taccgaaccg gtcgctcagc gccgaaaaaa atacccgcgc gtaggtgggc
     7201 tccagcaaaa gcggttgatt gaacgccctg gcggcgaggt gcggaaaatt gttccacggc
     7261 atcagttacc tccccagccg ttatcgttgg tatttgaggg gtgagataca gaccatgacg
     7321 gttcgctcag ccccatttca cgccggcgct gaatttcgta ttcctgctgc tccataacct
     7381 cctcgtaatc ctgtccctgc agcgccagtt cgttctgata cgtgctgagg ccagttgtga
     7441 tgcgcatggc gctctcctga acctctttca gcccatcaat cgccatgcga ccagcgccga
     7501 tccagagcgc gttcgtccag gagttccgcg cctcataaaa cgaccggaca gctgagcgtg
     7561 gcagggtgat aattccgcgt gccagcgcct cttcaaacca gcagcagaac atcagcgacg
     7621 cctgtcgcgc ggcgataaaa cgtcgacgcc ccatgaaaaa tcgccagctg acgttagcac
     7681 tggcccgggc gctggagtaa ctgacctggc tgtagtcccg gctaagttct tcgtatgacg
     7741 cgccaacgcc agctgcaacg taacgcagga gtgatttttc cagtgaacta aaaccagcat
     7801 cagcattctg agcggtctgt aaactgagtt tgtcgccggg atgcaggtgg ggaactttca
     7861 caccaccgag cttgatattt gcgccgttgt agtacgtcac gtaactctga ataaacgaat
     7921 tcagcgggtt cgagtcgata tcagtacccg cgccggcgat atattcaaac gcctgctggc
     7981 tgtcgagctc tgattcgatt gtcgcggcat acatcgcctt cacaatggcg ctctgcagtt
     8041 gtgtttgctg cagtgtgtcg agcattttca ggcgctccat gacgctgtaa aaaatattgt
     8101 ccccgcgggt ctgtccgtcc tcgagcggct cgaatatgtg gatgaatgcg tgtctgccgc
     8161 tgctgagctg tgctgggata cgccggcatt taccgactcc gccgagaggg taagtatcct
     8221 cggctatcca gtacccgacc gcggccccgt ttttatcgat atcaacaccg gcgcggcgaa
     8281 attgagtgtc agctgcgtaa cccggatttc gaatccgttt cggtgagacc attttgaatc
     8341 gcgtccgaaa aacgctgccg gcactactct cccagactgg ttgtacgcag gtttcaccgt
     8401 tgaaagcgtg agtagccacg ccctcgcgga tcatcattgt gaacgtccgt ttccgctcga
     8461 tatcaatcgt gcagtgaggg tcctcggcgt attcagtcca cgctacctcg acgtcacgcg
     8521 ccagcgccct ggcgtcctcg cgagatatgc cgaggtaacg ccagttaggg cgataactca
     8581 acttaaacag attgccgacg atatgatcct ggtgcagctg cacggcgttc gacgcgacgc
     8641 cgttattgcg aacgagatcg tctgctcgcg cgttaccgcg ataaaaattc ggcaacagtg
     8701 ctgcgtcggc gctctgctgt ggtgcgttcc agtcaatcag ctggccaccg aaaccgggac
     8761 cgccgccgtt ataccccgcg taacggcgta gtggcgtttt accgtcaggc ccgagcagct
     8821 gctgcggagc agtcataatc gaactcccac gggccgacgg cgtcccgtac tcagaccgag
     8881 ctgtgatttc agctcgataa tgtacgttcg gagctgctca atactcgcct gcgagtattg
     8941 atagctccgg ttatttcctg ctgaatcgcc gtgagacagc gacacggtcg atttacccgt
     9001 taataatttg tgcagagcga tttccgcttc cagcagtcgt tctgttaaaa cctcgcgcga
     9061 cgtcattagc tccctccgag cattctggcc atctcctcga gagacagttt gttttgtgat
     9121 tttttccgtt gctcagcgag cgtctcgaga ttgagctgga aacgaatttt actgatacgc
     9181 agcgctgcca gtccgtacac ccagcagtcg agcgcctcat ttcgccggcc ctggttgtcc
     9241 caacgataaa cgacgcgacc gttaatgagt ttcgggatca gaacctcgga gacgagctgt
     9301 tttgcctctg tcgtgctgaa tatttcgtcg tcgttgggaa aatgaatcgc acctggtgtc
     9361 gccgatttgg agtcgggttc cagctgcagg cgcattgcga gcaggtcttt cgctgtatct
     9421 gtcccaatca acgacaaata cactttattc gcgttacggg tacgaggcat atttacgacc
     9481 ggctggccgt atgagctcgc gcccttgatt ggaatgaccc acagcggacc gagtttcagc
     9541 gagcggttat aaacgacctg cgcatctata ccaccggtat cccacgccca gcgactgacg
     9601 ccgattgtgg tcccgtcgct gcgccggtat tgtttgcgaa tcactccgtc gacgcgctgc
     9661 agcgtgtcct cctcgtcgta gcgaccgagg acgattgttt tatcaatcag ccagcactcc
     9721 tcctcggctc cccagcccca cacataacac tcgtagcgcc cggacgtctg agagtcgatg
     9781 ccgccggtta tataaacaac accgtcagga acctggctgg cgtatttttc ccggcgatta
     9841 accagaatat cgtgctccag ctgctcgctg gccacgtcgc tccagagttc gccgagcgtc
     9901 gtgttatgaa acgtcttttc cttgagcggg tcgcctttcg ctttcagcca ctcgctgaca
     9961 atctcgcccc atccatcgag gtttagtgaa tacagggcgt ttatcacgat cgcagcgtgt
    10021 ttcggcgcgc gaacgacgcc accgtcatga tcaaaaaaat gaatgccgtc tcgggtccag
    10081 gtgcagtcct cggctatcca gcgccccccg aactccattt tttcgagatc gcgatagtaa
    10141 aaatgttccg ggcagtggca gcactggtaa tacgcggacg acgatttcgc ctcattggtc
    10201 tgcaggctgt tatcccattt gaggccgtat tcgataccgt cgaaaccaaa taccaggacc
    10261 tgctcctcgc cacaatgcgg acatgtcagg taaaaacgaa acgtcagatc ggcagcgtct
    10321 tcgagcattt cgatatgact tttgccggta acggtcggcg tcgaaccaaa aatcgccttc
    10381 gggtacgctg cccctttaat tcgaacgagc gccagttcga tgggcgagcc ctcgcctttg
    10441 ccttttttgg caacttccag cggccagccg tcaacttcgt caccctcgac aacctgtttc
    10501 gttagtcgcc ggaaatttcc tggtgcactc gcgccgcgaa aatcaagaat cgcgccgctc
    10561 atttctttac gctggagatt gttacgctcg ttgcttttat cccagtcggg gaaaattttc
    10621 tgaatcactg gcatttcggc gatagcgggg tcaacctcgt cggcgacaaa tccatccgat
    10681 tcgtcatcga taggctgata gaccacggca ctacgttttt tgtgctcagc gaaatagagc
    10741 agcgccgcga cgagtatttt tgtataaccg agacgagctg atttgcgaac agacacgatt
    10801 tttatcgcgt cgttcgtcat catattgagc atcactacct ggaccggctg agtcgtccag
    10861 tgcccagcga tgtggctgga gccctcaggg agataaaaat atttatcagc ccactcaaca
    10921 cccgtcatcg gtatcgtcac gcgcaaggga ttcaaccctg tcgagatcgc gttcgatatc
    10981 gctgacatcg taatcgctga agtcgattcg tatgtctgac aactcattta aggctatcgc
    11041 cagctcctct cgtaatacac tgctcgcctc ttgcggcatc tccggccaga cctttttcag
    11101 gcgtggtggc cacgactcga cgcgggtacg taattcaacg gcgacgcgag atacagcgac
    11161 gctaattaat tcaattggcg cgtagcgttt agcgagaatg cggcgtttta ctcgtgccat
    11221 caggattcgc tcctgtcgtt cctcattttt cagccactgc tcgcgatttt tttcgggaga
    11281 attgtccccc gcttccggtt cgtcattact agttgtgtcg cgtctattgc tccggagata
    11341 acgaatataa aaatggcgcc atgcgtctag ctcccaatca ccacgtcctt gtgggactgg
    11401 tgctcccgga agttttgcga gatcgcgcag acgacgatca gatagcagta aatgtgctgc
    11461 aacctcagcc tgacttgcca ttaaaaatcc tcaccggaac cggaaatacc caaaatgaaa
    11521 aaatactaaa aacgagcgag tttttgcgcg tctaccgacc ctcggtgttt tggatttcgg
    11581 aaaggacccg cgaccagggg gctatctccc tttcaggaca ggaattaggg gctcgcatca
    11641 ggttcatcaa actcaactgt agcctcgcgg cgtacttgtt tgcatacatc agctttgtgt
    11701 atctgattat cagcgtaagc tttcactttg gcagcgagcc atccttttgt gctgtatcga
    11761 tagactaccg aacaagtttt ccatatatgt atatatcttg aacttattga tatcattaca
    11821 gaaaaacaac aaccatgaga acgcaaaaaa tgaacagaga aaaaattgaa gccttaatga
    11881 gcgtaatatt aaaagaagct gacccaaaaa agtttcctga gaagttatca gaggacgcca
    11941 tcgtatcttt ttatcgtgcg aactcctctt atctaaattg ttcaacttta agagaatggc
    12001 taagcggcga agcagagcct tcagatgaga tacttcagaa gattatggtt cagaacaact
    12061 ggcgcgcaac aaaatggtca aatcagttac cttaatctgt tgaatgtgtg ccgccttaaa
    12121 acaaaaaggc ggcctctcgt taaagtaaat taccctattt tccaccaagg catgaagcct
    12181 ctgccccggt tgaatcaata caaccaccgt tcgcagtagt aatcttcgta cccggcgcga
    12241 tcatcacgtg tttaatactg ctgccgtcag cgcgagtcgc ttcggtgtat gtcgaatgtg
    12301 tgcagcctgc cagcgtgaag aacgcgacag ctaagagaag ttttttcacg ttttacctac
    12361 gcttctgaga tagatttctc agcattcacc aatggaagtg attgtggaac atccgtttga
    12421 cctgctggcc agcggtagcc tgttacgcgg gaacgaggaa aagctttgat atttacttca
    12481 tctgcctggt tgccccccaa aatcattaaa tccccggcgg catttttccc gacaacaaag
    12541 ccgacgtgac caccgccaga ccgagacaga atagcaatgc atccataggc gggttccttc
    12601 agttcattac cccaatcgag ataagaattc gcagactcaa aacgcgttga gcgaataccc
    12661 gcacgttcca gcattgcccc ggtgaaagca gcgcaccacg gtgtttcgtc atccttaatg
    12721 ccgccgcgtt tgatatcttt ccagtactgc acaatttctg cagcatgttg cttccctttc
    12781 atttcccgaa tgccgaggtt ttttcgagcc tcgattagcc atttaggatc cgtcattacc
    12841 tgtctcctgt tatttttgaa atattccctc gtgcccgcca gacagcaata cagatggtga
    12901 ggttgagaaa gaactctgcg ggatcaacct gcgtatattt cccgtaaaaa attcgtaggg
    12961 ctatccacgc agcagacaga atcgcgaggt aagcagttag tgagatgaaa aaacgatagc
    13021 ggcctgtttt ttgaaaaaac atcaaccgta gtgccaacat cagacaaata attgcattgg
    13081 cattgatgag gacagagtgc agggtcatta tttcatcccc ttatctgatt tccataaacg
    13141 agcttgtgac atgatccgca acagtgatgt aacgctgatt actgatgcaa ccagtgcacc
    13201 aatggcggga gagactttta ctgttacggg agggttcagg tgactcagca ccgcgttcag
    13261 aataccggta atgatggctg acgctgtctc agcgcaatac acaccgccaa caaacgaaat
    13321 gagtgcgaaa ataacctgct tccagaatcg atgctgcccg gacgacaaca catagagagc
    13381 tgcgcctgcc agcgcacaga tcatcactgc aggtgttgcc tcaggaaata acgcagcaaa
    13441 cgtcaccccc gccgagccag cagcaacgcc agcggttaga ggttcagaca tgatttttcc
    13501 tgattcagaa acgacaaaac cccgccgtgg cgaggttctt agaaatttgg caacatacca
    13561 aattagcgtc aaatatggcc tattttgttc gtttttgcaa gcattatacg caaacgtcgt
    13621 ctaaatggtt ctgataatga tgcaaagttg caagaagtgc cacttcatca agtgctctca
    13681 ccgcctcttt cattcctacc cagtgcaggg agtatgtttc gcaccaggtg gaacgagaaa
    13741 ccgacagcat tcctgctagg gtagatccgg ccatctcctt aaaatcctcg cgtttatttg
    13801 ctgctgcgac cgcctgcacg gacaaccaca ccaacgaaag caggcgctta actacttttc
    13861 tctgagttga cgcggggatg tttcctttat agcgactcca gacagcctca caaatagctg
    13921 tttggtgttt gaatgccagg ttaccaccgt agcaataacg caaccacgct tgctgacttg
    13981 catccagcga gttcacagaa cgccgccagg atgaatcagc aaattcaaaa tcactcatcg
    14041 gcggcgcggg gcgacgtctg ctgaaacttt ccagagcgta aactggcgta accagagcat
    14101 caacggtccg gtcctccagc tgcacacggt gaatatgttt gcgtgggtat gcgtttttgt
    14161 ctgccggtgg gtgctcacac aatgcttcca gttgcccctt agaaccacca gacaaatccc
    14221 gcaatgcagc gcgcagtttt atgcgggtat attccaataa atactcgtta ctcatcagat
    14281 aaactcctca tcgcgccaga tagccagtgt tctgaaaact ccctcagcgt gcatcaacaa
    14341 caatgagtcg tgctcgtaat ccgtttttgt acgtccgtcg atggcatcgt gacacgcact
    14401 gcaggcgata gcgccctgca tatcgtgagg tttgatggct gtgccgcacg ttccggcgag
    14461 acgataatga gccagtacgc tggtttcagg attgtgattg cacacaccgg ggatacgcac
    14521 agtacaagcg cgactgcgtg cagcttttct caggtcgatt tttttcatga tgtgtaatcc
    14581 agcagctgcg cggcggcatt ttcagcggcc tcctgagagg caaatgtgcg gaacaaaata
    14641 taattccaca gcacatctaa aacggctgaa tacagttgac cgaactcaag atcgtccatc
    14701 gctgcaaacg agattgaacg aggtacgcgc atcaaactgc cgtctggcat ctgatgaacg
    14761 tcataaaacc cagcttccat aatcgcccat gcgcgaaacg cctcgaacga cttcaccgca
    14821 ctgatactcc ccgcgcgctt ttccgactca tcgagaagat actgatcagc cagctctgcc
    14881 atgacatcac cgtgtccacc gtaatacgcc agtaacttaa cgtagccgtg aaccagttcg
    14941 cgctccgcag gagaaatagc ccctccggac ggatgccagt aatcaaagcc caggttgaga
    15001 agtgagaaaa atttacgatg aaacgcggga ttacgcgcct gtttgaaatc tgcatacaca
    15061 acagcacctg gtttgactcg ttcagtcaac cagcgttgcg tgtctggtgt cgcgggtatt
    15121 agcgaaccgc cggataccct gataaatgaa tgctgcgcca tggttaactc caggtggcgc
    15181 ggcagtgttc agaaaatgat gccgggtgtt caatccagca ccgatattat accgtgtttt
    15241 acgcgtcagg gggtgtaata gtatatccag ctatttctgc caactcgaga aacgccatca
    15301 ggctggcaat ccgctcatca tcggtcagaa cacgcacacc aacgatgtgt ccgtccttac
    15361 gcttgataac agcccggcat gtttccggta gttcgcctat agattcttga atattcatgt
    15421 cttcccccca atgccacaac ctgtatattt atacagtatt ttatggcatt tgtcataacg
    15481 ccaaatacaa tgagggaata atgaacaatt atattcacgt cgtgaatttt attaaacggt
    15541 tttatagggg attaaaccgt ttatggtcat tatttatcac tcctgtaaat tggaattaac
    15601 cattttctaa tcgtcgacgc tgcaggtggg tcagagtatt tcgccacaaa aataccggat
    15661 atgtattgca cgccacgcga taatggcgct gtcgggtttt cagtaaaaaa acgatcagcc
    15721 agttcaatgg cttcgctttt taatctgtgc tgtggtcgtc ctccgccctt tgttcccagg
    15781 tatcgcgcca gttgtttgaa acggtaggcg atgattaacg gtcgcatcat catattgaaa
    15841 aaatcgcggg catcgttgtc agcgccttgc gctatcaaca gtgcaaaaaa cagatacggg
    15901 attatgtaca cttcaggaga tatacgaacc cgttcacaag ttggtggagc caactcaata
    15961 agtaagtcag ccagcggatt ccccttttct ccacgtttgt aatagcgata cagcggcccg
    16021 atatcaagtt cactcacgtc gatttcagga tgcccggcaa cgactgtacg tatctcttct
    16081 gccagagcgt caaatattgc cccggtccgt tcaagataga gcctccgggt cgaaccgcga
    16141 tcatccaacg cccgtaacat atctaaccgg ctaacgaaag tttcaggcca gtcctcatag
    16201 aaggttttca taattacctc gaataataaa aactgcacta tttgcacaat ttattattcg
    16261 ttttcacgcc gctgagttct ataaaaaaga aaaaacctcc gaggcagggt tttgttatgg
    16321 ctcgttaaat catcatccaa ctttttagac tgaacggtga tacttgcaaa tatttgaaaa
    16381 tatgggctgg aaccctatct tatgatgtgc ctggtaattt atattgttgg gtctttatat
    16441 catgaggaat cactatgggt acgttaggca accagccgtg cagaagtcgt tatgagttcg
    16501 atgattttaa tttagccaat cgagctgcgg ctcttactaa gttagcaaaa gaaactggtg
    16561 tatcggtgga taccttaatc aaacttgaaa ttgctatgca actgaatcgg ctcaactcca
    16621 tccttatcga aaacggtgac aagatggacg agaatctggc aggtattggc gagatactgc
    16681 agaagtgaga gtagcccctc ttctgagggg ttgcacattt aaaatattaa gggcggtctt
    16741 cttcacgtac acagtcacct ggtcgaatcg ttcacgcata ctgagtacaa aaaatctcaa
    16801 cgataagatc aggttagacc tgtattttcc agaaacatat agacgcctaa aaaaacacta
    16861 aactcatgat tatcatgtat gtttttactg gaaacattga accatccaca atacagcgta
    16921 aaaagcaagc aattcacaag attttaaagt gatttatctg gaagacttta ctactaacag
    16981 ttaatatcgt accagaagtg cagaatttgc acttttacag gaatgtggta cggaacatgc
    17041 tgtctatatt tcaaccaata atcgtaatgc agtaactgga ggagctatgg ctaccaaccc
    17101 aagagagcac gcccggcgag tgctggacac gttctggtgc gggcgtggtt tccctgttga
    17161 tccagcgaaa attgctcacg acatgggatt agatgttttt attaccgatc ttcctgggaa
    17221 agtttctggc gcactgatta aacaaaaaga tcaagatcca gcgatctttc taaacagtga
    17281 tgacaacaaa gttcgtcaac gtttttcatg tgggcatgag ttggggcatt acatcgcccg
    17341 gcaagcatcg catagcgatg aatatgagta cgttgattta cgtggcgaaa ccgcaagcgc
    17401 cggaacgcat cctgatgaaa tttttgcaaa caagttcgca gcagaacttc tgatgccggt
    17461 agatgaggtc agaaaactgc acgctgacgg tcaaccaagt tatataatgg cgcattattt
    17521 tggcgtatct gacgatgcga tgacttatcg tttaaagaac ttgaggttgg ggtaacgctt
    17581 taaaatgcca tcggatgacg attttaacag ccgtttcaaa caggaagtag cacgcagact
    17641 gaaggattcc ctcaacctac accgtcagtt agcagaagag gttgagccgg aggacgatga
    17701 aactccggtt cagtctcctg acgaagcttc acctcagcca aaggtttcgc acgcccccaa
    17761 aaaaacggct gtccgtattc gcggaatagc cagaaaaaga gctgccgaag ctcgcaaaat
    17821 ggctgtagct gcgtctagca aaagaattcc aactgctaca ccctctcaac aagtcacccg
    17881 tactgagagt aaaatcttga ccgagttcac atctgtgaaa caggtgaatt cacttgatac
    17941 cgagcatgag cgcaaacaac tcaacaacaa agattttgaa gcagaaatcg ctctaaaaaa
    18001 acgatacggg aaatggttcc tgattatcct tgctttccaa cttctgataa tgaatggtgt
    18061 atttattgcc gacggcgcag gtaagctgga atttgaggat ttaacactac agttgtacat
    18121 gggcggtact ttgacagagg tattcggcct cgtgctggtc gtgacaaaat acctttttaa
    18181 acgcaagtaa ctctctcggt ccaacagtct ttcgaaggcc ctgatcaaag ggccttgata
    18241 aattagcagt gcgttgaaaa cagatagtta ttcccatcag ttccaacgta atacacatca
    18301 aaaaaatcac cattcttttg ctctaacgtc aacacctacc cttaaaaaaa taattctcca
    18361 agaatgagaa agttattgtg tgtattagat aagatatgag ctgacacatc tatggcgtgg
    18421 agccaaattt aatatgacag tccgctctgt gccataagcg gactgtcaat aaacagattc
    18481 acttgtaaat cttgaagcta tacatattta ctttcaatga taaataaaag aactatccaa
    18541 aaatcactga gagc
//
LOCUS       DAFGPF010000095        18412 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFGPF010000095 DAFGPF010000000
VERSION     DAFGPF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18412
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.095"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(277..1023)
                     /gene="cutC"
                     /locus_tag="LSX49_003713"
     CDS             complement(277..1023)
                     /gene="cutC"
                     /locus_tag="LSX49_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBL7170073.1"
                     /translation="MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLNTLNNLTELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DAHADEYSRYVVDGAAVAEMKGIIERHQAK"
     gene            complement(1037..1603)
                     /locus_tag="LSX49_003714"
     CDS             complement(1037..1603)
                     /locus_tag="LSX49_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL7170074.1"
                     /translation="MANWQSIDELQDIASDLPRFTHALDELSRRLGLDITPLTADHIS
                     LRCHQNVTAERWRRGFEQCGELLSENMINGRPICLFKLHEPLQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            1819..3552
                     /gene="argS"
                     /locus_tag="LSX49_003715"
     CDS             1819..3552
                     /gene="argS"
                     /locus_tag="LSX49_003715"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBL7170075.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEINEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            complement(3605..3997)
                     /gene="flhe"
                     /locus_tag="LSX49_003716"
     CDS             complement(3605..3997)
                     /gene="flhe"
                     /locus_tag="LSX49_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HBL7170076.1"
                     /translation="MRALLAILLFPLLVQAAGEGMWQASSVGVTLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPAGLRVRLCSQSRCVELEGQSGTTMAFSGIPAAEPL
                     RFIWEVPGGGRLTPPLKIQRNEVIVNYR"
     gene            complement(3997..6075)
                     /gene="flhA"
                     /locus_tag="LSX49_003717"
     CDS             complement(3997..6075)
                     /gene="flhA"
                     /locus_tag="LSX49_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBL7170077.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NVVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PAEPKPVKMAENNSVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPARYRILMKGVEMGSGDAYPGRWLAINPGTAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(6068..7216)
                     /gene="flhB"
                     /locus_tag="LSX49_003718"
     CDS             complement(6068..7216)
                     /gene="flhB"
                     /locus_tag="LSX49_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HBL7170078.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIINDPNLILGQIILLIREAMLALLPLISGVVLV
                     AIISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRTFSAQTGAELLKAILKTILVGSVTG
                     FFLWYHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(7405..8049)
                     /gene="cheZ"
                     /locus_tag="LSX49_003719"
     CDS             complement(7405..8049)
                     /gene="cheZ"
                     /locus_tag="LSX49_003719"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HBL7170079.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVIDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQGQVDDLLDSLGF"
     gene            complement(8060..8449)
                     /gene="cheY"
                     /locus_tag="LSX49_003720"
     CDS             complement(8060..8449)
                     /gene="cheY"
                     /locus_tag="LSX49_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HBL7170080.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(8464..9513)
                     /gene="cheB"
                     /locus_tag="LSX49_003721"
     CDS             complement(8464..9513)
                     /gene="cheB"
                     /locus_tag="LSX49_003721"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HBL7170081.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELARSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(9516..10376)
                     /gene="cheR"
                     /locus_tag="LSX49_003722"
     CDS             complement(9516..10376)
                     /gene="cheR"
                     /locus_tag="LSX49_003722"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBL7170082.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRALGLADFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLAKQY
                     TVPGPFDAIFCRNVMIYFDQTTQQEILRRFVSLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(10491..10621)
                     /locus_tag="LSX49_003723"
                     /pseudo
     CDS             complement(10491..10621)
                     /locus_tag="LSX49_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310622.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tar ligand binding domain-containing protein"
     gene            complement(10667..12328)
                     /gene="tar"
                     /locus_tag="LSX49_003724"
     CDS             complement(10667..12328)
                     /gene="tar"
                     /locus_tag="LSX49_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HBL7170083.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQSELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYHTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLAAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLAATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF"
     gene            complement(12473..12976)
                     /gene="cheW"
                     /locus_tag="LSX49_003725"
     CDS             complement(12473..12976)
                     /gene="cheW"
                     /locus_tag="LSX49_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBL7170084.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(12997..14961)
                     /gene="cheA"
                     /locus_tag="LSX49_003726"
     CDS             complement(12997..14961)
                     /gene="cheA"
                     /locus_tag="LSX49_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBL7170085.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEA
                     DQITFETVDVSPKISTSPMLKLAAEQAPTGRVEREKTTRSSESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSMQGTGTTIRILLPLT
                     LAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(14966..15892)
                     /gene="motB"
                     /locus_tag="LSX49_003727"
     CDS             complement(14966..15892)
                     /gene="motB"
                     /locus_tag="LSX49_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HBL7170086.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKRPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLNGGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(15889..16776)
                     /gene="motA"
                     /locus_tag="LSX49_003728"
     CDS             complement(15889..16776)
                     /gene="motA"
                     /locus_tag="LSX49_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HBL7170087.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLEFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLASVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(16903..17481)
                     /gene="flhC"
                     /locus_tag="LSX49_003729"
     CDS             complement(16903..17481)
                     /gene="flhC"
                     /locus_tag="LSX49_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HBL7170088.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(17484..17834)
                     /gene="flhD"
                     /locus_tag="LSX49_003730"
     CDS             complement(17484..17834)
                     /gene="flhD"
                     /locus_tag="LSX49_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HBL7170089.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAT
                     TLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLN
                     DVNQPEEALRKKRA"
BASE COUNT         4460 a         5062 c         4481 g         4409 t
ORIGIN      
        1 atatgattta ttacaatgta atcattaatt gctaaggaat aacccagttg ttatttagaa
       61 tatatatttg tcagttttgg caatttaaat cacataatga atgtgaatat atagaatatt
      121 tctagcacaa tgctatgcgc actgtcaccc gctcaacaga tcacggcaat cgttcgtttt
      181 ttatactact cagggataaa aaaaggcccc tgttgaaatt gcaggggcct ggtacgagca
      241 agcatcatat tgggcgacat gatgcaacgg taaaaatcat ttggcctgat ggcgttcaat
      301 gattcctttc atttcagcaa ccgccgcccc gtctacgaca taacgcgaat actcgtccgc
      361 gtgtgcatct gatgacatgg acaatccttg attacgataa cgcatcggtg aggcttgcca
      421 cgctcccgcg gagctatgga cttccagcac tccggcatcg aggaagtggt gcaggttttc
      481 cgcacggact cctgctccgg ccataatgat tggagcatca cgatgggcaa taagttccat
      541 aatttttgat aaaccttgca gtgcgtctga tttttgccct gatgtcagta cccgggcaat
      601 gcccaattcc gtaagattat tgagtgtatt taaagggtta gcgcacatat cgaaggcgcg
      661 atgaaaagtc actgccagcg gaccggcagc agccattatt ttttccattc gtggcatatc
      721 gacattcccg tcaacatcga gaacgcccgt caccagtcca ggaaaaccta attcgcggac
      781 tgtgcgcaca tcttcaagaa tggcggcaaa ctcaccgtcg ctgtagcaaa aatcaccacc
      841 gcgtgggcgg ataatcggat gcactgggat cgtcacccgc tggcgcacgg atttcagtac
      901 ccccaacgac ggcgttaggc ccccctcttt tggagctgcg cataattcaa ctctgtcagc
      961 gccgttttgc tgcgccgtta gcgcgcattc catgctgtaa cagcaaattt ccagtaatgc
     1021 catttttgct ccttagttac gccgactgct cgctggcaac gatctcttca atggaccacg
     1081 gatgaaactt aatggttgtt ttaccatcgg tgaccgccag cgtcggattc ggtaatcgtt
     1141 catgctcacc ttttggcgaa ctggttttaa ctgagatccc cggcaggctg agtccttcat
     1201 cagaaagcaa tgccagcgca cgggcattca gcgtttctgg atcacccggt agaacgattt
     1261 caatatgttc ccaaccttcg tgcgggtaac gtttttcccc gggccacggt agctccacaa
     1321 tggaaaactg ccagtgcgca acctgtagcg gttcatgcaa tttaaacaaa caaatcggtc
     1381 tgccattgat catattttct gacaaaagct cgccgcactg ttcaaacccg cgacgccagc
     1441 gttcagcggt gacgttttga tggcaacgca aagaaatgtg atcggcagtc agcggagtga
     1501 tatccaaccc cagacggcgg gaaagttcat ctaatgcgtg ggtaaatcgc ggtaaatccg
     1561 atgcaatatc ctgcagctcg tcgatagatt gccagttcgc cataatcatt cttcgtcttt
     1621 cattaaaagc gttaatttac cctgttgccc tgcgccaacc aaccgctgat ttcacgccgc
     1681 ttctgatgca atagtgaaaa cggcaatacg ccacgcgcac gttgctgacg aaaacagcca
     1741 tttgcagtat actcccgccc taatttcttt aactggtgcg ggtaattttt gctcgcttca
     1801 tcaatgtaag gtattccggt gaatattcag gctcttctct cagaaaaagt ccgtcaggcc
     1861 atgattgcgg caggcgcgcc tgcggattgc gaaccgcagg ttcgtcagtc agcaaaagtt
     1921 cagttcggcg actatcaggc taacggcatg atggcagttg ctaaaaaact gggtatggca
     1981 ccgcgacaat tagcagagca ggtgctgact catctggatc ttaacggtat cgccagcaaa
     2041 gttgagatcg ccggtccagg ctttatcaac attttccttg atccggcatt cctggctgaa
     2101 catgttcagc aggcgctggc gtccgatcgt ctcggtgttg ctacgccaga aaaacagacc
     2161 attgtggttg actactctgc gccaaacgtg gcgaaagaga tgcatgtcgg tcacctgcgc
     2221 tctaccatta ttggtgacgc agcagttcgt actctggagt tcctcggtca caaagtgatt
     2281 cgcgcaaacc acgtcggcga ctggggcact cagttcggta tgctgattgc atggctggaa
     2341 aagcagcagc aggaaaacgc cggtgaaatg gagctggctg accttgaagg tttctaccgc
     2401 gatgcgaaaa agcattacga cgaggatgaa gagtttgccg agcgtgcacg taactacgtg
     2461 gtaaaactgc aaagcggtga cgaatatttc cgcgagatgt ggcgcaaact ggtcgacatc
     2521 accatgacgc agaaccagat cacctacgat cgtctgaacg tgacgttgac ccgcgatgac
     2581 gtcatgggtg aaagtctcta caacccaatg ctgccgggta tcgtggcgga cctgaaagcc
     2641 aaaggtctgg cagtagaaag tgaaggcgcg accgttgtat tccttgatga gttcaaaaac
     2701 aaggaaggcg aaccgatggg cgttatcatt cagaagaaag atggcggcta tctctacacc
     2761 accactgata tcgcctgcgc gaaatatcgt tatgaaacac tgcatgccga tcgcgtgctg
     2821 tattacatcg attcccgtca gcatcaacac ctgatgcagg catgggcgat cgtccgtaaa
     2881 gcgggctatg taccggaatc cgtaccgctg gaacaccaca tgttcggcat gatgctgggc
     2941 aaagatggta aaccgttcaa aacccgcgct ggcggtacgg tgaaactggc cgatctgctg
     3001 gatgaagccc tggagcgtgc acgtcgtctg gtggcagaaa agaacccgga tatgccagcc
     3061 gacgagctgg aaaaactggc taacgcggtt ggtattggtg cggtgaaata tgcggatctc
     3121 tccaaaaacc gcaccacgga ctacatcttc gactgggaca acatgctggc gtttgagggt
     3181 aataccgcgc catacatgca gtatgcttac acgcgtgtat tgtccgtgtt ccgtaaagca
     3241 gaaattaacg aagagcaact ggctgcagct ccggtaatca tccgtgaaga tcgtgaagcg
     3301 caactggcag ctcgcctgct gcagtttgaa gaaaccctca ctgtggttgc ccgtgaaggc
     3361 acgccgcatg tgatgtgtgc ttacctgtac gatctggccg gtctgttctc tggcttctat
     3421 gagcactgcc cgatcctcag cgcagaaaac gaagaagtgc gtaacagccg tctgaaactg
     3481 gcacaactga cggcgaagac gctgaagctg ggtctggata cgctgggtat tgagacagta
     3541 gagcgtatgt aatcgcgtta tacggcaaca gccgatgtca ttgcagacat cggctttttt
     3601 atcattaacg ataatttaca atcacttcat tccgttgaat ctttagcggc ggagttagcc
     3661 gcccaccgcc aggcacttcc cagataaagc gcaacggttc tgccgccggt ataccggaaa
     3721 aggccatggt ggttccactc tgcccctcca attcgacaca acgagattgt gaacacaagc
     3781 gaacccgcag tcctgcaggt gtcggaccga taagctgata acgccacgcc accagcgtca
     3841 tcaatcctga agcaggttgt cgcgtagaaa gaggcgctga cgacatcgat tcaccgcgat
     3901 gatttagcgt aacgcccacg ctactcgcct gccacatccc ctccccggcg gcttgcacca
     3961 gcagcggaaa caataatatt gctaataagg ctctcattat ttgccgccaa tcgtcgccgt
     4021 catacggata tgtcggttat ctgatagttc cagattcgac agcaccacta actgcggcaa
     4081 gctgcggcgc aggaagcgag acaataatgg tcgtagcgcg tggttcacca acaataccgg
     4141 cggcgcaccc aacatctcct gacgggatag cgcttcctga gtttgcgcca gtaaacgatc
     4201 cgccagccct ggctccagtc caccaccgcc ttgcaacgcc tgtagcaaca aacgttccag
     4261 cggtgtatcg aggccaataa catggacttc atctttgcca ggaaaccact gctgggtaat
     4321 cgcccgtccc aacgctacgc gcacgacagc ggttaattca tgcggatcgc tttggatggg
     4381 cgcatgttcc gccagcgttt cgagaatggt gcgcatatcg cgaatcggca ctttttcatc
     4441 gagcagattt tgcagcactt tatgcagtgt ggtaagcgtg acgacgccag gaacgagatc
     4501 ttccgtcagc tttggcatct cctgggcgac gcgatccagc agctgttgtg cctcctgacg
     4561 accaaacagc tctgcggcat gctggctaat gaggtggtta agatgcgttg ccaccaccgt
     4621 gctggcctca accacggtgt acccctgaat ctgcgcctgt tctttaagcg cactttcaat
     4681 ccagatagca ttcaggccaa atgccggatc aacggtcgct tcaccaggta atgttccggc
     4741 ggcagtgcct ggattaattg ccagccagcg ccccggataa gcatcaccac tccccatttc
     4801 gacacctttc atcaagatac gatagcgggc tggttgcaaa tccatgttat cgcggatgtg
     4861 caccactggg ggtaggaagc ccatctcctg ggcaaatttc ttgcggatac tgcgtatacg
     4921 gcccaacaac tcaccatcct gctgaaaatc aaccatcggg atcaaccgat accccacttc
     4981 cattcccaga gaatcttcca gttgtacatc gttccacgtt gcttcgacta ccgaattatt
     5041 ctctgccatt tttaccggtt ttggttcggc aggcgctttt tgttcacgtc cgcggatcca
     5101 ccaggccagc cccagcaatc cggcagtgaa cagcaaaaat accaggtttg gcattccagg
     5161 caccaggccg agtaaaccga gcacggcggc gcttaataac ataacgcttg ggttactgaa
     5221 aagctgattc accatctgct cgccaacatc ctgatcggtg ctgacacgcg taacgatgac
     5281 ccccgcggcg gtagaaatca ccaacgccgg aatttgtgcc accagaccgt cgccaatggt
     5341 caatagcgta taactttccg ccgcgtgccc catgctcatg ccatgttgca gcacaccgac
     5401 cagcaatccg ccgacaacgt taatgaccat gatgaggatc ccggcgatgg catcgccgcg
     5461 aacaaactta cttgccccgt ccatcgagcc gtaaaaatcg gcttcctgag tcacttcgga
     5521 gcggcgtttt ttcgcttcat cttcaccaat caatccggcg ttaaggtcgg cgtcaatcgc
     5581 catctgctta cccggcatac catcgagaac aaagcgcgcg cccacttccg caatacgccc
     5641 ggcacctttg gtgataacca taaagttgat gatcacgaga atgacgaaca ccacgatacc
     5701 gatagcgaaa ttgccaccga cgaggaagtg accgaacgct tcgaccacct ttccagccgc
     5761 cgccgcgccg gtatgccctt ccatcaaaat gatacgggtt gaagccacgt taagtgccag
     5821 acgcaacagc gtggtaaaca acagaatggt cggaaacgca gcaaactcga gcgtgcgctg
     5881 ggtaaacatc gccaccagca acaccatgat cgacaaggca atattgaagg taaacagcag
     5941 gtcgagtatg aatgcgggca gtggcagcac catcatcgac aagatcaaca ggatcaaaat
     6001 cggtccggca aggatctgcc attgtgtcga tttcaggttt gcgggcaggc gcagcatcgc
     6061 ggccagatta ctcatgggtc ggtttctcgt taataaaatc cagggcttcc ggcaccggaa
     6121 gatgagtagg ttgtacaggg cgctgtccac cagccagacg ccagcgtttc agttgccaga
     6181 cccaggccag cacttccgcc accgcggcgt acagttgacc cgggatttgt tgaccgatct
     6241 ccgcatgtcg atacagcgca cgcgccagcg gcggcgcttc aagcgtcggg acgttatttt
     6301 cagcgccaat ttcacgaatg cgcagcgcga ccagccctgc acctttagcg accactttcg
     6361 gtgcgctcat tttgttttcg tcatactgca acgctaccga atagtgggtc gggttattga
     6421 caatgacatc cgctttcggc acatcggcca tcatccgacg ccgtgcggcc gctcgctgca
     6481 tctgacggat ccgcccttta acatgggggt cgccttcgct ttgtttgaac tcatcacgaa
     6541 tatcctgccg tgacattcgc agctttttca ggtggctgaa gatttggaaa aagacgtcaa
     6601 atcccaccat tggaatgaca ccaagcacca ccagcagcgc gcatagccct accagatcca
     6661 ttgcattacc catggcggta atcggagact cggccattaa gcgcatcatc tgcggccagt
     6721 gataccagag aaaaaacccc gtcacgctgc caaccaggat ggttttcaaa attgccttaa
     6781 gcaactccgc gccagtctgt gccgagaacg tccgtttaat gcccggtagc gggttgagtt
     6841 tggaaaactt cggctgcaag gattttccgc taaataccag cccccccagc ataaccggag
     6901 aaataatcgc caccagcacc acgccgctaa tcagcggtag cagcgccagc atggcttctc
     6961 tgatcagcag aataatctgc ccgaggatca gattcgggtc attgataata ctgtgatcaa
     7021 aatgtagccc tgcggagagc atgcccgaca atcgacgggc cagcgacaca ccgccaaacc
     7081 agataacact aacgcccacc agcaaaatca gcagtgaagt cagttcacgg gaacgcggga
     7141 tttgcccctc ttcccgcgct ttttctagtc ggtgaggtgt gggggcctct gttttgtcgt
     7201 cgctctcgtc agacacgtcg ccaatcctgg aaagagtatt aagcgtaaat gatgccagag
     7261 cgcaaagcgt tcaatggttt gagtaagggg caaaacaggc gggatttagg gcttttactg
     7321 ccacacatca agcatagtat gcgtttgtcg gatgcggcgt catcgcctga tatgacgtgg
     7381 tcacgtcaca tcaggcaata caaatcaaaa tccaagacta tccaacaaat cgtccacctg
     7441 accctgactg gctaccacac cggctttgct ggtatcgacc tgaggtccat taagcaaact
     7501 ctggttttca cgttttggac gcgactcctg ttccgggatg ttttccaaca acaccatcag
     7561 caactgacgt tcgatctcct gaatgacatc catcatccgc ttaatgacct gcccggtgag
     7621 atcctgaaaa tcctgcgcca tcatgatttc cagcagttgc gcgttagtaa agctggtatg
     7681 cgcggggaca tctgccagaa attgccgtgt atcgatcacc agttcacggg cgtcggcaag
     7741 gtcaatcgga tcggcaaacc agtcatccca acgttgggtt aacgcttttg ctgatttctc
     7801 catttgatcc tgatgcggtt gtgacgcctc aacactgttc agcgcccgct ccgcagcctg
     7861 ggcggtcatc tgcacaacat agtacaaacg atcgcgcgca tcggggatgg cttccgctgc
     7921 ttcggcaatg gcctgatcca gccccagttc ccgcaaactg tcgcgcagca tacgcgtcag
     7981 gctgccgatg cgcgcaatga tatcgccagc tgaatgctcg tcagcaggtt tgattgatgg
     8041 ttgcatcata gtcgcatcct cacatgccca gtttctcaaa gattttgttg agtttttcct
     8101 ccagcgtcgc ggcggtaaat ggcttcacca catagccact ggcccccgct tgcgccgcag
     8161 caatgatgtt ctctttcttc gcttctgcag tcaccattaa cactggcaat gccgacatcg
     8221 cgccatccgc acgaatcgtt ttcagcaact ccaggccatc catattgggc atgttccagt
     8281 cggagataac aaatccataa ccgcctgcct gcaacttatt gagagcgtcg acgccatctt
     8341 ccgcttcctc aacattattg aatcccagct ctttcagcag gttacgcact atgcgtcgca
     8401 tggtggaaaa gtcatccaca accaaaaatt taagttcttt atccgccatt tcacactcct
     8461 gatttaaata cgtatcgcct gtccggcact aatttttgcc agcatttgct gacttacctg
     8521 gctaagatcg accacttcgc agacaccacc catattgatg gcctcgcgcg gcatgccgaa
     8581 caccacgcaa cttgcttcgt tttgcgcaag ggtccatgcc cccgcctgac gcatcgccaa
     8641 cattcccgcc gcgccgtcgt tgcccatacc ggttaggatt accccaaccg cattacgccc
     8701 cgcctgtttg gccacagaat ggaacaacac atctaccgat ggccgatggc gattaaccgc
     8761 cgggccatcg tgaattttga tttgataatt tgcgccacta cgcgccagct ccatatgccg
     8821 atcgcccggc gcgatatagg catgtcccgg caagacgcgc tctccatctt cggcttcttt
     8881 aaccccgatc tggcaaagct tattaagtct gtcggcaaaa gagcgggtga aaccgggcgg
     8941 catatgctgg gtaattaaca gtgccggact ggaaagcggc aacggttgca gtacgtgacg
     9001 aattgcctca gttccccccg ttgaagcacc aatcgcaatc agtttttcag aactcaacaa
     9061 cggccccgcc ttcagcgttg tcggtgccga caatggctta tgtgctgcaa ggctcgcctt
     9121 tgctgccgta cgcacctttt cagcaatcat ttcgctatac gccagcattc cttcgcgaat
     9181 acccagttgc ggtttggtga caaaatctat cgcccccaac tccagcgcgc gcagcgtgac
     9241 ttctgaccct ttgccggtca gggaagaaac catcacaacg ggcattggac gcaaacgcat
     9301 taatttttcg aggaaatcca gtccgtccat ccgcggcatt tcaacatcca gcgtcaatac
     9361 atcgggattg aatttcttaa tcaaatcacg cgcaaccagc ggatcagggg cggtcgccac
     9421 catttccatg tcgctatggc tgttgatgat ttctgtcatg atctggcgca tcagtgccga
     9481 atcatcgaca gataacaccc tgattttgct catcgttaat ccttacttag cgcatacacc
     9541 gtctgaccac gcagcgtgaa gcggcgctca aggtggctaa agttttcaga gtgacccgca
     9601 aacagcaatc cgtcgggttt aaggagcgaa acaaagcggc gcaaaatctc ctgctgggta
     9661 gtttgatcga agtagatcat gacgttacga cagaagatcg catcaaacgg ccccggcacg
     9721 gtgtactgtt tcgccagcaa attcagcggg gcaaaatcaa catagttcgc cagctcctga
     9781 cgcacgcgta ccagcccttc atgcggtccc gtccctcgca tgaaataccg ttgcagttgc
     9841 tgcggcgtca ggtttttcaa ctcttcatgg cgataaatac cgcttctggc tttttccagc
     9901 acttcggtgt cgatatcgct ggcaaacact ttccagcgtc cgggcgcggt gcccaatgta
     9961 tcagccagcg tcatcgctat gctgtacggc tcttcgccgg ttgaagccgc cgcgctccat
    10021 acgcgatact cgccagaacg gcgacgtgcg tgatccgcga gcagaggaaa atggtgtgcc
    10081 tcacggaaaa atgccgtcag attcgtggtc agcgaattga taaacgcctg ccactcaccg
    10141 ctgtgctgat tagattccag caagttcagg taatgaccga aatccgccag tcccagcgca
    10201 cgcaaacgac gaaccagtcg gttgtaaacc atgtcgcgtt tatggtcagc cagaacgatc
    10261 ccggcgcgtt gatagatcaa ttgacttatc cgccgaaaat gcgcgtcgga aagcgccagg
    10321 cgctcggtca tctgtaacaa taaagacgtt tgcccacagg gcagagatga agtcatagcg
    10381 ccttctcaat cacttcagga taccactggc gcaatttgta actgcgccga ctcatgtcgt
    10441 gctacttcat gttcttcaag ggtaaatacc gccacacgcg acgaaagatg gtcggcctga
    10501 ttcagtcgtt gcaaatcgtc gcgaaatgcc caaaagacat gccgttactg ccaatctgca
    10561 agatcccgca gagaatcaaa attaaaaaca gcgtggtcga aattcgaata cgattaaaca
    10621 tcaacgctcc ccatcaggcg gcaatgaccg ctttagtaaa tactcgtcaa aatgtttccc
    10681 agtttggatc ttgttcagca attcgcagtc gtggctgtgc cggtggttgc tcactggcag
    10741 gacgggatgg tgtttgcggt ttattggtga gtgggctggc tgccagacgg aacgcggaaa
    10801 ccgcttgcgt taaacgactc gcctgttctt ccagcgcagc tgcggcggca gctgattcct
    10861 gcaccagcga tgcgttctgt tgcgtgacgc gatccatttc cgaaaccgcc aatgcgactt
    10921 gatcgatgcc acgactctgt tcatccgatg ctgatgcaat ctcgcccata atgtcagtca
    10981 cgcgagtgac agcattgacg atattgttca ttgtttcccc tgcgctttcg accagcaccg
    11041 aaccggtatc aacgcgcgag acggagtctt caatgagggc tttgatctct tttgccgcct
    11101 gggcgctgcg actggcaaga ttacgcactt cgcccgccac cacggcaaaa ccacggcctt
    11161 gttcacccgc tcgcgcggct tcaacagcgg cattcagcgc gaggatatta gtctggaagg
    11221 caataccatc gataacgctg ataatgtcgg caattttctt cgaactatcg gcgatctcat
    11281 gcatcgtttt cactacgcca tccaccactt tgccgccgtg ctgggcggtg tcggaggcac
    11341 tttgcgccag ttgcgaggcc tggcgggcgt tatcggcgtt ttgcttcact gtcgcggcga
    11401 gctgctccat gctggcggca gtttcttcca gcgcggatgc ctgctgttca gtacgggagg
    11461 aaagatcggt gttgcccgcc gcaatttcac gggtaccggc atagatggca tctgaacctt
    11521 cgcgcacatg agtgacggtg tcagtcaaag agcgttgcat atgtgaaacg ctctgcgcca
    11581 ggtcgcccat ttcactgcgc ccgtcaatgg tcagggtatt cgccaggtta ccaccggcaa
    11641 tttcgcgaat atgcgcaata atttttgcca gcggtgtaag caacatacgg cgaatgccgt
    11701 accacgccgc cagcagaatc aataccacca ccagcgcgat aaccgccagt tgccactggg
    11761 caaatcggta atcatctgcg ttgtcagtga cgatatcgcg atacagtttt tcactgctga
    11821 gggcgtactg agcaaacgct tctcccattg cattttgcat tccctgggtt ggctgagcga
    11881 aataagctcc agtattgcca taatcaagat aatcaatcag ttcagttaac gctgtgtgat
    11941 agtttttata tttttcatca atattacgac tggtagcgac catttcaggt aacggtgcca
    12001 tgcttttgaa ttttttataa tgagtcgcgg cctgggccaa tgttttcctg gcgctatcga
    12061 gcaattcaac tttggcatta ctttgctgat tggatgaatc catcatcatc cgcaccgctg
    12121 aacgactcag gttaatgcgc gtttgtagca ttaaatccca tgttgacgtc agctcgctct
    12181 gctgttcccg taattgattg gaaaccacaa agctcttctg gctatggtga agggaagaaa
    12241 aaaacagact gccggaaata agctgtaaca gtgcgaatac ccccagcacc attaccaaca
    12301 gcgtgactac gcggatacgg ttaatcataa ggcaccttcc tgaaaacaag ttgatctcgt
    12361 tatcggcaag gaggggggaa actttattgc tgatgccacc cgccgcgaaa ttgaaataaa
    12421 aaacccgatg cgcagatcat cgggttcatt tcaattgagg acatcgggag aattacgcca
    12481 cttctgacgc cgcgctatct aacagcgcca tctcttcgct gttcagcagt ttttcgatgt
    12541 tcaccagaat caacatgcgg tcgcccagtg cgcccagtcc tgtgagatat tcggttgaaa
    12601 gcgtcacggc aaattccggt gccggacgaa tttgctccgc cgtcaatgaa agcacgtctg
    12661 agacgccgtc aaccacgatg ccgaccaccc gctgtccgag attcaggacg ataactaccg
    12721 tgttgtcgtt atagtccaca tccacctggc tgaacttaat tcgtaagtca acaatcggca
    12781 caataacgcc gcgcagattc gtgacgcctt tgataaacgc tggcgtgttc gcaatccgtg
    12841 tcacctgatc gtagccacgg atctcctgca ctttcagaat atcaataccg tactcttcat
    12901 caccaagggt aaataccaga aattcctggc ctgacggctc gctggccagc tttgttacat
    12961 tcgtcatacc ggtcatattg ttaccttttt actcattcag gcggcggtgt tcgccatacg
    13021 ttgttcgcgg tttatcgcct gcaaggcgga gacatcaaca atcagtgcca cgctgccgtc
    13081 gccaagaatg gtcgcagcag aaatgccggg gactttgcga tagttacttt caaggttttt
    13141 aaccacaacc tggtgttgac caattaattg atccactagc aaggcgtagc ggcgaccgcc
    13201 actttgtaag atcaccacaa ttccctgggt ggcttcggtt ttcgcgcccg cgacgttgaa
    13261 cactttccac agttcgacga taggcagata ttcaccccgc acttccagca cccgctcgcc
    13321 gccagccagt ggatgcagat cggcttcacg gggttgcagt gattccatga cagcattcag
    13381 cggcagaatg aaaacttcat ccgcaacgcg tacggacatg ccgtcaagaa ttgccagcgt
    13441 cagcggcagt aaaatgcgga tcgtagtgcc agtaccctgc atcgactgga tctcgacatg
    13501 accgcccatc tcctggatat tacgtttaac gacgtccatg ccgacgccac gcccggagac
    13561 gtcggtgacc tgctccgccg tggagaagcc aggtgcaaat atcagcattg caacttcgtc
    13621 gtcgctcatg ttttcgctga cggtcagacc ttgcgaggcc gcttttgcca gaattcgttc
    13681 acggtttagc cccgccccat cgtcggtcac ttcaatgcaa atgttgccgc cctgatgttc
    13741 ggcagacaga attaaatttc cgacgctgtt tttacctgca gcgagccgtt tttctggcag
    13801 ttcaataccg tgatcgaggc tattgcgtac caggtgggtc agcgggtcga taatgcgttc
    13861 aatcaggctc ttgtcgagtt cagtagaact gcccaccagc gtcagttcta cctgcttgcc
    13921 gagttttccc gccagatcac gcaccagccg gggatagcga ctaaagacat attccatcgg
    13981 catcatgcga atcgacatca ctgattcctg caaatcacgg gcgttacgtt gtaactgccc
    14041 catgctggta atcaaatcac catgattaac cgggtccagt tcgctggaac gctgggcaag
    14101 catggactgg gtgatgacca gctcaccgac gaggttaatt aattgatcaa ccttttctac
    14161 cgctacacgg atgctggtgg attcactgct gcgcgtcgtt ttttcccgct ccacgcgacc
    14221 ggttggcgct tgttcggctg ccagtttaag cattggtgag gtggatattt ttggcgagac
    14281 gtctactgtt tcaaaggtaa tctgatcggc ttcaatcaca aaacagagta ccgctgtgat
    14341 gtcatcttcg gcgatgtcgc ccggtaatat tgccgagagg gaatcagccc ctttcaccac
    14401 gtcagttaac gttgtcagat gccccagctc ttcttccagc aggtcgactt cgccggcctt
    14461 caggcgcgaa aggataattc gtcgcggtga ctgactacga ctctgctcat cttgtggttc
    14521 acttttggca accacactta atcgggtcac tgcggatggc gtttcgcctt tcgcttctaa
    14581 tgccagttga cgcaaggcct ggcagatata atcgaagctg gcggcatccg gctcttgcga
    14641 ctgtttataa gcgtcgagct gttcttgcat gatgtccttc gtttccaaaa acagattgat
    14701 aatgtcggtg ttgagttgca tctcacctcg tctggcttca tcgagcaggt tttccatcag
    14761 atgcgtggtt tcctgcaaaa cgctgaagcc aaaggttcct gcccctcctt tgatcgagtg
    14821 ggcagcccga aagatggcat tcaattgttc ggcatctggc gcttccggct gcaaaaccag
    14881 cagatgctgc tccatatcag ccaacagttc gtccgcttca tcaaaaaatg tctgataaaa
    14941 atcgcttata tccatgctca cgctgtcacc tcggttcggc tgatggcatt gtgggaacac
    15001 tgacctgtgg tgcaacctca ggtttttcca gggcgcttac tggctcattc tggctttcgg
    15061 cgttttcatg caaaatggcc tgttcggctt gtttgttcag taccagcagg ctgatgcgac
    15121 ggttgacggc atcatcaggt ccgcgatcgc ttaagcgcat cgttgccgcc atgccgacga
    15181 cacgtaacac tttgccgcca ttcaacccgc caaccatcag ttcgcggcgg gatgcattgg
    15241 cacgatcggc agaaagctcc cagttgctgt aacctttctc accgctggcg tagggaaaat
    15301 catcggtatg acccgagagg ctaattcggt tgggaatacc gttcagtacg ggcgcgatgg
    15361 cgcgcagaat gtcgcgcata tagggttcga cgtcggcact gccagttcta aacatcgggc
    15421 gattctggct atcgatgatc tgaatacgta gaccttcctg gaccagatcg attttgagat
    15481 gtggacgtaa cgcccgcagt ttcggatcgg actcaatcaa ctggtcgaga tcgccacgca
    15541 atttccgcaa tcgactttgc tccatgcgtt ttttcagctc ttcgatgttc ggccgcttat
    15601 tcacttcccc ctggctttgg gtgtaatcat caccaccgcc gggaattggg ctttcactat
    15661 tagaaatgcg atcgccgccc gtaaccgctg tcgccagcgg agtccggaag tactccgcaa
    15721 tctgaatcag ctcttttgga ctggagatag agatcagcca catcaccaga aaaaaggcca
    15781 tcattgcggt cataaagtcg gcataagcaa tcttccacga tccatgtgct gccccgtggc
    15841 ttttggcttt acgtcgtttg acgacaataa tcggatgcgc ttgattcttc atgcttcctc
    15901 ggttgtcgtc tgttgttgcg gatttttcac cgcacgcaca tgctcttcca gctcaataaa
    15961 cgacggacgt tcgctggaat agagcgtttt gcgaccaaac tcaacggcga taggcggtgc
    16021 gtaaccgttc agatttgaaa gcagagtgac tttgacgcac tgcatcattt tgctggtttc
    16081 ggcgcttttc tgacgtaaaa cactcgctaa tggggaaata aatccgtaag ccaataaaat
    16141 accgaggaaa gtccccacca tcgcatgagc gataagcgcc cccagctcgg cggcaggacg
    16201 atcggctgaa cctaacgcgt gaactacccc cattacagcc gcaacaatac caaaagccgg
    16261 aagtgagtcc ccgaccagcg ccagactgtt cgccgggact tctgcctcgc tttcgtgcgt
    16321 ctcaatttct tcatccatca gggcttcgat ttcgaaggtg ttcatgtgac cgctgataat
    16381 caggcgcaga taatcgacga taaattcaag catgacgcta tccgcaagga tgcgtgggta
    16441 gctggcgaag atctcgctct cacggggatt ttcaatatcg cgttccagcg aaaacatccc
    16501 catctgccgc gatttcgcca tcaaccgata aagcagagcc agcagatcca tatacattgc
    16561 tttggtgtat ttggagcgac gaaacagcaa cggcagcgcc ttcagcgtgc ctttaatcgc
    16621 tttgccatta ttgccgacga taaacgaccc aatccctgca ccggcaataa tcaccagttc
    16681 agcgggttga tagagtgctc caaggcttcc accggtcatc aaataaccgc cgaaaactgt
    16741 accgagaaca accaggtaac ctaataagat aagcacgaca tcatccttcc actgttgacc
    16801 atgacaggat gttcagtcgt caggcgttaa cacgcgatag gggcaaaaaa aagcagcggt
    16861 acgtcgttac cgctgctgga atgtttcgcc acaccgtatc agttaaacag cctgtactct
    16921 ctgttcatcc agcagttgtg ggataatatc ggcaggattc tgggaaagtt tacgtctttt
    16981 tactgcccgg gatggcggct gacataagct gcaggcaaag ctgccaacag gctggtgagc
    17041 atgggtaata aaattgccgc cgcagcagtt gcagctggaa agttgcagta atccactttc
    17101 aacaaaccgc accaatgtcc aggcacgggt taatgccagc agcggtcctt cttctgcttg
    17161 cgggcactgt tcaaggtata aacggtaggc tttgatcacc gcatcgacgc cattacacaa
    17221 gccagttttc agtaaaaact gccatgcatt acagaacatc gaagcatgaa cattttgttc
    17281 ccaggtcata aaccagtcgg ttgaaaatgg cagcatgcct ttcggcggtg ggcttccgcg
    17341 cagttcttta tagagtttta tcagacgtcc gcgacttaac tgtgtttcgc tttccagcat
    17401 ctgcaaacga gcgcccaggg tgatcaattc cattgccagc tgaatatccc gcgcttcctg
    17461 aacaatgctt ttttcactca tgatcaggcc cttttcttgc gcagcgcttc ttcaggctga
    17521 ttaacatcat tcagcaagcg tgttgagagc atgatgccgg tatgaatttg ctggagatcg
    17581 tcaacgcggg aatcttgcgt caactgagta atcgtctggt ggctgtcaaa acggaagtga
    17641 caaaccagtt gattggtttc tgccagctta accatttgcg gaagagtcag tgccgctaac
    17701 gttgtcgcca tttcttcatt tatgccgaga cgaaacatag cggacgcttt gtcctgaaca
    17761 atcagacgct gtgcaagtag taaatatgac aagttgatgt cataaatgtg tttcagcaac
    17821 tcggaggtat gcattattcc cacccagaat aaccaacttt atttttatgc ggtctcaccg
    17881 caccccgtga tgtcgccggg aagccccggt aaaaaataat tagcattaga atagttgcga
    17941 taagctgcaa taagcagacc cacctttttg gtttaataag tccttacaaa tagaaggggg
    18001 tctttacact tatctaagat ttttcctaaa tcgacgcaac tgtactcgtc actacacgca
    18061 catacaacgg aggggggctg cgattttcaa taatgtgtga tgcagatcac acaaaacgct
    18121 caattactta acataaatgt ataagtcata cttttgtttt gggtgtattt caatctgtta
    18181 aaaaattttt cgctacactg gcaagcaaaa atgaaacagg aataatcgaa atgggatgtt
    18241 gcgtacagtt aaaataactc accgtaaata atcatctgct ataaataatc gctttaatgc
    18301 aataccaggt aagccatttt taaacaaaca cttaccgcac aacaaactaa ttaactacaa
    18361 agaaaggcaa caatcaacct aatgttaata aaatgcttta catatattaa cc
//
LOCUS       DAFGPF010000096        18318 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFGPF010000096 DAFGPF010000000
VERSION     DAFGPF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18318
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.096"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(326..916)
                     /locus_tag="LSX49_003731"
     CDS             complement(326..916)
                     /locus_tag="LSX49_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170090.1"
                     /translation="MRTPSRYIFRLPSHEINPFRATLLLILLICAVLAGVSWLILSFV
                     RTGNTFIFWLTLFIGYLIAIAKQEKIKLIEKRQIMADKRQGLSICQFARQFSPHTVDT
                     WVIRAVWNTLQGNGYIDYPLPLKASDKLDDDLDLVNDADELEELVEDIAARCGRDLRG
                     IEDNPFLPITTVGSLVSVLNAQPMTQERRSLLFTRS"
     gene            complement(966..2162)
                     /gene="hemY"
                     /locus_tag="LSX49_003732"
     CDS             complement(966..2162)
                     /gene="hemY"
                     /locus_tag="LSX49_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HBL7170091.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTL
                     QNNPPQ"
     gene            complement(2165..3370)
                     /gene="hemX"
                     /locus_tag="LSX49_003733"
     CDS             complement(2165..3370)
                     /gene="hemX"
                     /locus_tag="LSX49_003733"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBL7170092.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     AIALAAGVGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAVQLE
                     QANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRL
                     ADNDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFITIRRRDDTAVPLLAPNQD
                     IYLRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQL
                     SQQNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPAPAPAPAPQAD
                     APAAAPQGE"
     gene            complement(3392..4132)
                     /gene="hemD"
                     /locus_tag="LSX49_003734"
     CDS             complement(3392..4132)
                     /gene="hemD"
                     /locus_tag="LSX49_003734"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HBL7170093.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGRQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPTYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKCALILRGNGGRELIGDSLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQSREVTTVVVTSGEMLQQLWSLIPQWYREHWLLRCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            complement(4129..5070)
                     /gene="hemC"
                     /locus_tag="LSX49_003735"
     CDS             complement(4129..5070)
                     /gene="hemC"
                     /locus_tag="LSX49_003735"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBL7170094.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSLIIRGER
                     RGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            5457..8003
                     /gene="cyaA"
                     /locus_tag="LSX49_003736"
     CDS             5457..8003
                     /gene="cyaA"
                     /locus_tag="LSX49_003736"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HBL7170095.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQEHDAPLLQQYFS"
     gene            complement(8043..8363)
                     /gene="cyaY"
                     /locus_tag="LSX49_003737"
     CDS             complement(8043..8363)
                     /gene="cyaY"
                     /locus_tag="LSX49_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HBL7170096.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            complement(8489..8674)
                     /locus_tag="LSX49_003738"
                     /pseudo
     CDS             complement(8489..8674)
                     /locus_tag="LSX49_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580503.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DKNYY family protein"
     gene            8833..9036
                     /locus_tag="LSX49_003739"
     CDS             8833..9036
                     /locus_tag="LSX49_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL7170097.1"
                     /translation="MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            9073..9897
                     /gene="dapF"
                     /locus_tag="LSX49_003740"
     CDS             9073..9897
                     /gene="dapF"
                     /locus_tag="LSX49_003740"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBL7170098.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGIGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            9894..10601
                     /locus_tag="LSX49_003741"
     CDS             9894..10601
                     /locus_tag="LSX49_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HBL7170099.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLARWIERV"
     gene            10598..11494
                     /gene="xerC"
                     /locus_tag="LSX49_003742"
     CDS             10598..11494
                     /gene="xerC"
                     /locus_tag="LSX49_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBL7170100.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIIHFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            11494..12210
                     /gene="yigB"
                     /locus_tag="LSX49_003743"
     CDS             11494..12210
                     /gene="yigB"
                     /locus_tag="LSX49_003743"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HBL7170101.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            12294..14456
                     /gene="uvrD"
                     /locus_tag="LSX49_003744"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             12294..14456
                     /gene="uvrD"
                     /locus_tag="LSX49_003744"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HBL7170102.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLETV"
     gene            complement(14511..15413)
                     /locus_tag="LSX49_003745"
     CDS             complement(14511..15413)
                     /locus_tag="LSX49_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HBL7170103.1"
                     /translation="MKKTLATLFLLTCLGSSSAYADNALILQTDFSLKDGAVSAMKGV
                     AFGVDHNLKIFDLTHEIPPYNIWEGAYRLYQTASYWPQGSVFVSVVDPGVGTDRKSVV
                     LKTKNGQYFVSPDNGTLTLVAESLGIESVRQIDEKTNRLKGSEKSYTFHGRDVYAYTG
                     ARLASGAITFEQVGPELPAKVVELSYQKAKATKGEVKGNIPILDIQYGNVWSNISDEL
                     LNQAGIKLNDTLCVTISEGSQQKYAGKMPYVASFGDVPEGQPMVYLNSLLNVSVALNM
                     DNFAQKHQVASGADWNIDVKKCAK"
     gene            complement(15496..16260)
                     /locus_tag="LSX49_003746"
     CDS             complement(15496..16260)
                     /locus_tag="LSX49_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HBL7170104.1"
                     /translation="MAHRLFIGKGMITLNLKRIFLTLTLLPLFAVAADDCAPSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADINSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     LLMENGVINPRIHPNVASRKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGEAIPWQRYPFVTMISVEQKG"
     gene            16630..17580
                     /gene="corA"
                     /locus_tag="LSX49_003747"
     CDS             16630..17580
                     /gene="corA"
                     /locus_tag="LSX49_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HBL7170105.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            complement(17623..18003)
                     /locus_tag="LSX49_003748"
     CDS             complement(17623..18003)
                     /locus_tag="LSX49_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HBL7170106.1"
                     /translation="MSKDYMADGSLTEKWKYRFSFYDEHGFPGFWGASPEYKQALKGL
                     NTRQKIIIRTNVIAFFFSWVYLFVLGLWKKAIVVLFLAIFSLIFGYMIGYNVFGFIIA
                     AYVSYNTNRWFYEKEVKGIHTWSL"
     gene            complement(18018..>18318)
                     /locus_tag="LSX49_003749"
     CDS             complement(18018..>18318)
                     /locus_tag="LSX49_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418262.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170107.1"
                     /translation="ICILLISFFSNAGAGFFVITSTILLHYLVINMNCQRLRDSGFTY
                     IKTYIFSTLVVYIISFIIMVAEHFDCSGNGSMIFLICYFSTFGMLVLAPTDSPRK"
BASE COUNT         4310 a         4751 c         4814 g         4443 t
ORIGIN      
        1 tgcgcaggag aaatattcac tcaggaagtt attactcagg aagcaaagag gattacagaa
       61 ttatctcata acaagtgtta agggatgtta tttcccggtt ctctgtggca taataaacga
      121 gtagatgctc attccatctc ttatgttcgc cttagtgcct cataaactcc ggaatgacgc
      181 agagccgttt acggtgctta tcgtccactg acagatgtcg cttctgcctc atcagacacc
      241 atggacacaa cgttgagtga agcacccact tgttgtcata cagacctgtt ttaacgcctg
      301 ctccgtaata agagcaggcg tttttttatg accgagtaaa caacaggcta cgtcgctctt
      361 gggtcatcgg ttgtgcgttt aatacactta caagagaacc taccgtggtg atgggaagaa
      421 acggattatc ttctattccg cgtagatcgc gcccacaacg agcggcaata tcttcgacca
      481 gctcttctaa ctcgtctgca tcgtttacta aatccagatc atcgtccagt ttatcactgg
      541 ctttcagtgg taatggataa tcgatatagc cgtttccttg taaggtattc cacacagccc
      601 gaatcaccca tgtatctacg gtgtgggggg aaaattggcg tgcgaactga caaatggaaa
      661 gtccctgacg tttatcagcc ataatctggc gcttctcgat gagcttgatt ttttcctgct
      721 tcgcaatggc tatcagatac ccaataaaaa gtgttaacca gaagatgaat gtattgcctg
      781 tacgtacgaa ggacagaatc agccaactta cgccagccag aacggcacat atcaacaaaa
      841 tcagcaagag cgttgcccga aaaggattaa tttcatgtga tggtaagcgg aaaatatagc
      901 gggacggtgt gcgcatgttt gacatccttg taaaaaaata tcgcccctga acgaggcgat
      961 atagattact gcggtgggtt gttttgcaac gttagcatca aaccgtcgcg acgcatcgct
     1021 gcggcttctt ccggcttgtg cagtctgtcc agcgcgtcgg caagccatgc gtaatcgtag
     1081 gcgtccggac gttgtttcag cgctgcgcgg aaggcgagcg atgcttcctg ccattctccg
     1141 tgtttcatca gcgactgacc cagtgtgctc cacaacagcg ggcgatcgcc cacgtttttg
     1201 atctgttggc gcagcacttt ttccagctgt tccggattat tggttttcag acgcgggatc
     1261 ggcagcagca ggcgatcgtc atactggcgt ttcaggccgt cgatgataat ttgctgggca
     1321 gtatcatgat cgtcacactc aataagatgt tccgccattg ccacctgcaa ggccacctga
     1381 tgacgcgttt tccggctttg gtttttccac cagttacgca aaccttcgct accgttatcg
     1441 gcacgcgcct gatccatcag gccaatccat gcctgttgtt ccagcattgc acgatgttct
     1501 tcatcaccaa catgggcttt cgccattgat gggatgatat ccagcagcga actccatgcc
     1561 cctgtgcgga tatacgcctg ttccgccaga cgtaatactt ccggatggcg tggcgtaact
     1621 tccagcagct tatcaacgcc gtgacgtgct gcatggtttt cattacgggc cagttgcaga
     1681 cgtacacggg tgatttctac cggaatggtg tcattgccgg ccagctccgc tgcgcgttcc
     1741 agatgttggt tggcgcgtgc ttcatcacca cgttgttgcg cggcttcggc tgccagtaga
     1801 tagttcacca ccggttgttc agcgtgatcg gcatttttcg ccatcagctt ttcaacttgc
     1861 tgataatcgc cttccgccag tttcagcagc gcctgttcgg tctgcttacg tgcacggcga
     1921 cgcttacgtc cgacaaacca cccacgggtg tgcgcgcctg tgcggaagat tcgccgcagt
     1981 agccactcaa tggcaaacag cactaccatc gccagaatca aaataatcgc gaggcccgtg
     2041 acgctagttt caatattgta gttgtcggtc tggatcagca cgtaaccctg atggccggca
     2101 atcatcgggc caaccacgat ccccgcaatc agcaacacaa agagcaataa cacttttagc
     2161 atggttattc tccttgcggc gcggctgccg gagcatcagc ttgcggtgca ggtgcaggtg
     2221 caggtgcagg tgcaggtgca ggtttagctt ccgttgtccc tgctgccggt tgtgccagca
     2281 ggttacgcac gcgggtctgc atcaattttt ccagcatcgc ctggctttgc agggtttccg
     2341 gaagatccat cgagatattt tgctggctta actggtccac ctcgtcgagg aacgctttgg
     2401 tggtggcatc atcagtatcg tagtaagcac gtacccaggt ggagacgttc tccagcgcct
     2461 ggcgataagt ctcttcctgg tgacgcggta cagcttgtgc tgcgaccagc aggcgagagc
     2521 ggatattttc gcgcagatag atatcctgat ttggcgctaa cagcggtacg gcagtgtcat
     2581 cacgacggcg aatcgtaatg aagttgtcca taaaattctg ccagcttttt tgcagattga
     2641 tacgccattc gctgatggaa ctggaaagct cttcaccgtc ggaatccatc ggcgaaccat
     2701 cgctgtcatt atcggccaga cgcagattat ctacctgatt tgaaagctga ttaagcttaa
     2761 ggatgatacc gtcataatcc acctgcgata ccgcagaaag gctggcgata tcatcggtaa
     2821 ttgcccggcg aacggtaatc agactcgggt cattcatatc cgccaggctg gcgtctgcac
     2881 ttttcagcaa cgctgcagcg gtcgtgacgt cctgatcgct ccacagcttc cgtccggcga
     2941 gtttcaccag aaaatcggcc tgggccagca gccaggtttt agcatcgctg ccggaaatgg
     3001 tggcgacctt ttgttggact tcatccagct gttttgccag cgtttcttgc tgacgattcg
     3061 cctgctcaag ctgtacagct tgttgcttga taatgccttc cagctcggct ttttggctct
     3121 cctgggcttt ttgcagtgcc gtaagttggt tagccagggc atcgctggtg gcagtctgat
     3181 tgacggcctg ttgtttaccc cagccataca aaccgacgcc cgccgccaga gcaatagcga
     3241 tagccaccgc gctgagaatc aatgcggtat tgttcttact ctttttttct gttgcgacag
     3301 gttgtgacgt ggtgtccacg gcctccctgg tctcttcaac cacggcggag gttttttctt
     3361 gttccgtcat tatggcttcc tgttatgaga gttattgtaa tgcccgtaaa agcgcatcgt
     3421 tgtcagcgtt atcggcgacc ttaatgtctt gccagcccag ttcccgggcg agtttcgcca
     3481 aacgctcact gacgaccaat agtcgacagc gtagtaacca gtgctcacga taccattgtg
     3541 ggatcagcga ccagagttgc tgcaacattt caccgctggt aacaacgacc gtcgtcacct
     3601 cgcgggattg ccagcgcatc gcttcttctg caccatcgta atggattgcg catcgttgat
     3661 aacattcaca aaaagtgacc tcagcaccgc gcgccgtcag ggaatcccca attagctcac
     3721 gaccgccatt gccacgtaat atcagcgcac atttgcccgc aatattttgt aattcaggta
     3781 attgtagcaa gacttcgctg atttcccgat cctgtgggta gagaatcttc tgtccgctta
     3841 cggtatgtag tgccagcgcg gtggtgcgtc caatggcgaa ataagtaggt agtcggggcc
     3901 atttacgatc ttgctgatgc agctgtgatt gggcaaaagc aaccgcgtgt tgcgagaggg
     3961 caaacaacag atcgctctct cccagcgctg ccagttgatc agcaagttgc ggtaattgtc
     4021 gacccggaga aaactcaatc agcggaaaat gccaggccac ctgccccagt gtgcgcagac
     4081 ggctcactaa ctcttctcct gcgggagacg ggcgggtgac caggatactc atgccggggc
     4141 gtctccgtta tagacttcag cgaggatctc gcgcgcgccg ttattcagta gctcttctgc
     4201 cagcgaaatc cccatttgtt cggcatcttg cggcgcaccg cggcgttcac cgcgaataat
     4261 cagcgaaccg tccggcgcgc cgaccaacgc acgcagccag atttcgccat caataagctc
     4321 ggcgtagcta ccaattggca cctgacatcc gccttcgaga cgggtattca tggcgcgttc
     4381 ggcggtaaca cgcagtgcag tttcgtggtg attcagcgcg gcgagcagct cgcgagtgcg
     4441 tgcatcatca aggcggcatt caatgcccac cgcaccttgc cctaccgccg gaagagaaat
     4501 ctcgggtggc aacgcggcgc gaatgcggga ctccagacct aaacgtttta gtccggctac
     4561 ggcaagaatg atggcatcgt attcaccgtt atccagtttg ctcaggcgag tgccgacgtt
     4621 gccgcgcagg gagcggataa tcagatccgg gcggcgttca gccagttggc actggcgacg
     4681 taaactggac gtcccgacga tactgcctgc cggtaacgca tccagactgt catagttatt
     4741 ggacacaaat gcatcgcgag gatcttcacg ctcgcaaata gtgaccagcc ccagaccttg
     4801 cgggaattca accggcacat ctttcatcga atgtacggcg atatcggcgc gattttcgag
     4861 gagcgcgact tccagctctt taacaaataa gccttttccg cctactttcg ccagcggcgt
     4921 atcaagaatc acatcgccgc gcgtcaccat cggtaccagt tcaacgacca ggcccggatg
     4981 gctcgccatc aacttgtctt tgacatagtg tgcctgccag agtgcaagtg ggctttggcg
     5041 tgtggcaatt cttaaaacat tgtctaacat gcttgttacc gtcattatca tccgtggtcc
     5101 atcctaacat ccttgccaga gcgatgtcag tgttgtggtg aaacgtagac gcctgcgcaa
     5161 accgtaaaat gaggtcgggc agtggatcct gacaggcgct ttgagccttc gtaataagga
     5221 atttacagag aataaacggt gctacacttg tatgtagcgc atctttcttt acggtcaatc
     5281 agcaaggtgt taaattgatc acgttttaga ccattttttc gtcgtgaaac taaaaaaacc
     5341 aggcgcgaaa agtggtaacg gttacctttg acatacgaaa tatcccgaat gccgcgtgtt
     5401 accgttgatg ttggcggaat cacagtcatg acgggtagca aatcaggcga tacgtcttgt
     5461 acctctatat tgagactctg aaacagagac tggatgccat aaatcaattg cgtgtggatc
     5521 gcgcgcttgc tgctatgggg cctgcattcc aacaggtcta cagtctactg ccgacattgt
     5581 tgcactatca ccatccgcta atgccgggtt accttgatgg taacgttccc aaaggcattt
     5641 gcctttacac gcctgatgaa actcaacgcc actacctgaa cgagcttgaa ctgtatcgtg
     5701 gaatgtcagt acaggaccca ccgaaaggtg agcttccaat tactggtgta tacaccatgg
     5761 gcagcacctc gtccgtaggg caaagttgtt cctctgacct ggatatctgg gtctgtcatc
     5821 aatcctggct cgatagcgaa gagcgccagt tgctacaacg taaatgtagt ctgctggaaa
     5881 gctgggccgc ctcgctgggt gtggaagtca gcttcttcct gattgatgaa aaccgcttcc
     5941 gtcataatga aagcggcagc ctggggggcg aagattgtgg ctccacccag catatactgc
     6001 tgcttgacga attttatcgt accgccgtgc gtctcgccgg taagcgtatt ctgtggaata
     6061 tggtgccgtg cgacgaagaa gagcattacg acgactatgt gatgacgctt tacgcgcagg
     6121 gcgtgctgac gccaaatgaa tggctggatc ttggtggctt aagctcgctt tctgctgaag
     6181 agtactttgg tgccagcctt tggcagctct acaagagtat cgattcccca tacaaagcgg
     6241 tgctgaaaac actgctgctg gaagcctatt cctgggaata cccgaaccca cgtctgctgg
     6301 cgaaagatat caaacagcgt ttgcacgacg gcgagattgt atcgtttggc ctcgacccgt
     6361 actgcatgat gctggagcgt gttactgaat acctgacggc gattgaagat ttcacccgtc
     6421 tggatttagt gcgtcgctgc ttctatttaa aagtgtgcga aaagctcagc cgtgaacgcg
     6481 cctgtgtagg ctggcgtcgc gcagtgttga gccagttagt gagcgagtgg ggttgggacg
     6541 aagctcgtct ggcaatgctc gataaccgcg ctaactggaa gatagatcag gtgcgtgagg
     6601 cgcacaacga gctgctcgac gcaatgatgc agagctaccg taatctgatc cgctttgcgc
     6661 gccgcaataa ccttagcgtc tccgccagcc cgcaggatat cggcgtgctg acacgtaaac
     6721 tgtacgccgc gtttgaagca ttaccgggta aagtgacgct ggtaaacccg cagatttcgc
     6781 ccgatctctc ggaaccgaat ctgaccttta tttatgtacc gccgggccgc gccaaccgtt
     6841 caggttggta tctgtataac cgcgcgccaa atattgagtc aatcatcagc catcagccgc
     6901 tggaatataa tcgctacctg aataaactgg tggcgtgggc atggtttaac ggcctgctga
     6961 cctctcgcac ccgtttgtat attaaaggta acggcattgt cgatttgcct aagttgcagg
     7021 agatggtcgc agacgtgtcg caccatttcc cgctgcgctt acctgcaccg acaccgaagg
     7081 cgctctacag cccgtgtgag atccgccatc tggcgattat cgttaacctg gaatatgacc
     7141 cgacggcagc cttccgcaat caggtggtgc attttgattt ccgtaagctg gatgtcttca
     7201 gctttggcga gaatcaaaat tgcctggtgg gtagcgttga cctgctgtat cgcaactcgt
     7261 ggaacgaagt gcgtacgctg cacttcaacg gcgagcaatc gatgatcgaa gccctgaaaa
     7321 ctattctcgg caaaatgcat caggacgccg caccgccaga tagcgtggaa gtcttctgtt
     7381 atagccagca tctgcgcggg ttaatccgta ctcgcgtgca gcaactggtt tctgagtgta
     7441 ttgaactgcg tctttccagc acccgccagg aaaccgggcg cttcaaggcg ctgcgcgtct
     7501 ccggtcaaac ctggggcttg ttcttcgaac ggctgaatgt atcggtacag aaactggaaa
     7561 acgccatcga gttttatggc gctatttcgc ataacaaact gcacggcctg tcagtgcagg
     7621 ttgaaaccaa tcacgtcaaa ttaccggcgg tggtggacgg ctttgccagc gaagggatca
     7681 tccagttctt cttcgaagaa acgcaagacg agaatggctt taatatctac attctcgacg
     7741 aaagcaaccg ggttgaggtg tatcaccact gcgaaggcag caaagaggaa ctggtgcgtg
     7801 acgtcagtcg cttctactcg tcttcgcacg accgtttcac ctacggctca agcttcatca
     7861 acttcaacct gccgcagttc tatcagattg tgaaggttga tggtcgtgaa caggtgattc
     7921 cgtttcgcac caaatctatc ggtaacatgc cacctgccaa tcaggagcat gacgcgccgc
     7981 tgttgcagca gtatttttct tgatgctaat gccggaaagc gaggcttatc cggcattagc
     8041 tcttaacgaa aactgacggt ttctcccgcc tgctgcgtcg ccgcctgttc cagcaaatcc
     8101 cagaaggttt cgccgctgcg atcgcaaatc cactcatcgc ctttcagatc aaaatggtag
     8161 ccgccctgtt tggttgccag ccatacctgg tgcagtggtt cctggcggtt gataatgatt
     8221 ttgctgccgt tctcaaaggt aatggttagt acaccgccgt tgatttcaca gtcgatatcg
     8281 ctgtcgccat cccagtcgtc cagacgttct tcaatggtca gccacagttg atcagccagg
     8341 cgatgaaatt cactgtcgtt cattgttgta tcctgttttt aagtgatggc ggcagtatag
     8401 cggcatgggg tcagggcttc aaagtttgcc cgtctgctgc tgcgttccgg catgattcat
     8461 ccgtcaccgg aataataata tctctatata gcgaaagatt ggtcttttca taagggcgca
     8521 aatacaccac gccttttccc tgtttctggt aaatattatg ttccggctca tcaagccgac
     8581 atccccatgc cgatgataag aacaacgaac aagacaataa acaaaccaca ttgcgatagt
     8641 gcataaagcc atcctggcgc gaggtgccga tcacgaaact accagcaaaa cataaatcgc
     8701 cacgagtaag cgttatactc gcagcatttc ctcacttttc agacttcata aagagtcgct
     8761 aaacgcttgc ttttacgcct tctcctgcga tgatagaaag cagaaagcga tgaactttac
     8821 aggcaatcca taatgaaaaa cgtgtttaag gcactcactg tattacttac tctcttcagc
     8881 ctgacgggct gcggtctgaa aggtccgctc tatttcccgc ctgcagataa aaacgcaccg
     8941 ccgccgacca aaccggtaga gacgcaaacg caatccacgg tgccggacaa aaacgaccgc
     9001 gccactggcg atggtccatc ccaggtgaat tactaaaagt cagtttctgt acccgcgtga
     9061 ttggagtaaa tgatgcagtt ctcgaaaatg catggccttg gcaacgattt tatggtcgtc
     9121 gacgcggtaa cgcagaatgt ctttttttca ccggagctga ttcgtcgcct ggcggatcgg
     9181 cacctgggga tagggtttga ccagctgctg gtggttgagc caccgtatga tccggaactg
     9241 gattttcact atcgcatttt caatgctgat ggcagtgaag tagcgcagtg cggcaacggt
     9301 gcgcgctgct ttgcccgttt tgtgcgcctg aaagggctga ccaataagcg cgatatccgc
     9361 gtcagcaccg ccaacggacg gatggtgttg accgtcaccg atgatgatct ggtccgcgtc
     9421 aatatgggcg aacccaactt cgaaccttct gccgtgccat ttcgcgctaa caaagcggaa
     9481 aagacctata ttatgcgcgc cgccgagcag acaatcttat gcggcgtggt gtcgatggga
     9541 aatccgcact gcgtgattca ggttgatgat gttgatactg cggcggtaga aacgcttggt
     9601 cctgttctgg aaagccacga acgttttccg gagcgcgcca atatcggttt tatgcaagtg
     9661 gttaagcgcg agcatattcg tttacgcgtt tatgagcgtg gggcaggaga aacccaggcc
     9721 tgcggcagcg gcgcgtgtgc ggcggtggcg gtagggattc agcaaggttt gctggccgaa
     9781 gaagtacgcg tggaactccc tggcggtcgt cttgatatcg cctggaaagg tccgggtcac
     9841 ccgttatata tgactggccc ggcggtacat gtctacgacg gatttattca tctatgaagc
     9901 aaccagggga agaactgcag gaaacactca cggagcttga tgaccgggcg gttgtcgatt
     9961 atctgattaa aaatcctgag ttttttatcc gcaatgcgcg cgcagtagaa gcgatacgtg
    10021 tgccgcatcc ggtacgcggc accgtttcgt tggtcgagtg gcacatggcc cgcgcacgta
    10081 atcatattca tgttctggaa gagaacatgg cgttgttgat ggaacaggct atcgccaacg
    10141 aaggcctgtt ttatcgtcta ctctacctgc agcgcagtct caccgccgcc agcagtctcg
    10201 atgatatgct gatgcgcttt caccgctggg cgcgcgatct cggcctggca ggtgcgagtc
    10261 tgcgcctgtt tccagatcgc tggcgcttag gtgcgccgtc gaaccacact catctggcat
    10321 taagccgtca gtctttcgaa ccgctgcgta ttcagcgtct ggggcaggaa cagcactatc
    10381 tgggaccgct taacggaccg gagctgctgg tggtgctacc ggaagcgaaa gcggtgggat
    10441 cggtggcgat gtcgatgctg ggaagcgatg ctgatttggg ggttgtgctg tttaccagtc
    10501 gcgatgccag tcactatcaa caagggcagg gaacgcagtt acttcatgaa attgcgctga
    10561 tgttgccgga gcttctggcg cgttggattg aacgcgtatg accgatttac acaccgatgt
    10621 agaacgctac ctacgttatc tgagcgtgga gcgccagctt agcccgataa ccctgcttaa
    10681 ctaccagcga cagcttgagg cgatcatcca ttttgccagc gaaaacggcc tgcaaagctg
    10741 gcagcaatgt gatgtgacga tggtgcgtaa ttttgctgta cgcagtcgcc gtaaagggct
    10801 gggagctgca agtctggcgt tacggctttc tgcgctacgt agcttttttg actggctggt
    10861 cagccagaat gaactcaaag ctaacccggc gaaaggtgtt tcggcaccga aagcgccgcg
    10921 tcatctgccg aaaaacatcg acgtcgatga tatgaatcgg ctgctggata ttgatatcaa
    10981 cgatcccctc gccgtgcgcg atcgggcaat gctggaagtg atgtacggcg cgggtctgcg
    11041 tctttccgag ctggtggggc tcgatatcaa acacctcgac ctggagtctg gcgaagtgtg
    11101 ggtgatggga aaaggcagca aagagcgccg cctgccgatt ggtcgcaacg ccgtggcgtg
    11161 gattgagcac tggcttgatt tgcgcgacct gtttggtagc gaagacgacg cgctttttct
    11221 gtcgaaactg ggcaaacgca tctccgcgcg taatgtgcag aaacgctttg ccgaatgggg
    11281 cataaaacaa gggctgaata atcacgttca cccgcataaa ttacgtcact cgttcgctac
    11341 ccatatgctg gagtcgagcg gcgatcttcg tggtgtgcag gagctgctgg gtcatgccaa
    11401 cctctccacc acgcaaatct atactcatct tgattttcaa caccttgcct cggtgtacga
    11461 tgcggcgcat ccacgcgcca aacgggggaa ataatgcgtt tttaccggcc tttggggcgc
    11521 atctcggcgc tcacctttga cctggatgat accctttacg ataaccgtcc ggtgattttg
    11581 cgcaccgagc gagaggcgct tacctttgtg caaaattatc atccggcgct gcgcagcttc
    11641 cagaatgaag atctgcaacg cctgcgccag gcggtacggg aagcggaacc tgagatttat
    11701 cacgacgtga cgcgctggcg ttttcgttcg attgaacaag cgatgctcga cgccgggctg
    11761 agtgccgaag aagccagtgc aggcgcacat gcagcaatga tcaactttgc caaatggcgc
    11821 agccggatcg acgtcccgca gcaaacccac gacaccttaa aacagctggc gaagaaatgg
    11881 ccgctggtgg cgatcaccaa cggtaacgcc cagccggaac tgtttggttt gggggattat
    11941 tttgagtttg tgctgcgcgc tggcccgcac gggcgctcaa aaccgttcag cgatatgtac
    12001 ttcctggcgg cggaaaaact caacgtgccg atcggcgaga tcttacatgt cggggacgat
    12061 ctcaccactg acgtgggtgg ggcaattcgc agcggaatgc aggcctgttg gatcagaccg
    12121 gaaaatggcg atctgatgca aacctgggac agccgtttac tgccgcatct ggaaatttcc
    12181 cggttggcat ctctgacctc gctgatataa tcagcaaatc tgtatatata cccagctttt
    12241 tggcggaggg cgttgcgctt ctccgcccaa cctattttta cgcggcggtg ccaatggacg
    12301 tttcttacct gctcgacagc cttaatgaca aacagcgcga agcggtggcc gcgccacgca
    12361 gcaaccttct ggtgctggcg ggcgcgggca gtggtaagac gcgcgtactg gtgcatcgta
    12421 tcgcctggtt gatgagcgtg gaaaactgct cgccgtattc gattatggcg gtgacgttta
    12481 ccaacaaagc ggcggcggag atgcgtcatc gtatcgggca actgatgggc actagccagg
    12541 gcggtatgtg ggtcggcacc ttccacgggc tggcgcaccg cctgctgcgt gcgcaccata
    12601 tggacgccaa cctgccgcag gatttccaga tcctcgacag tgaagaccag ctacgtctgc
    12661 ttaagcgttt gatcaaggcg atgaatctcg acgagaagca gtggccgccg cgtcaggcaa
    12721 tgtggtacat caacagccag aaagatgagg ggctgcgtcc gcatcatatt cagagctacg
    12781 gtaatccggt ggagcagacc tggcagaagg tgtatcaggc gtatcaggaa gcgtgtgacc
    12841 gcgcgggcct ggtggacttc gccgagctgc tgctacgtgc tcacgagttg tggcttaaca
    12901 agccgcatat ccttcagcac tatcgcgaac ggtttaccaa tatcctggtg gacgaattcc
    12961 aggataccaa caacattcag tatgcgtgga tccgcctgct ggcgggcgat accggcaaag
    13021 tgatgatcgt tggcgatgac gatcagtcaa tctacggctg gcgcggagcg caggtggaga
    13081 atattcagcg tttcctcaat gatttccccg gtgctgaaac tatccgtctg gagcagaact
    13141 accgctctac cagcaatatt ctgagcgccg cgaacgccct gattgaaaac aacaacgggc
    13201 gtttgggtaa aaaactgtgg accgatggcg cggacggtga gccgatttcc ctttattgcg
    13261 cttttaacga actcgacgaa gcgcgttttg tggttaatcg catcaaaacc tggcaggaca
    13321 acggcggggc gctcgctgag tgcgccattc tctaccgcag caacgcccag tcgcgtgtgc
    13381 tggaagaggc gttattgcag gcgagtatgc cgtatcgtat ttacggcggg atgcgcttct
    13441 tcgaacgcca ggaaatcaaa gatgcgctct cgtatctgcg cctgattgcc aaccgcaacg
    13501 acgacgcggc ctttgagcgt gtggtgaata cgccaacgcg gggtattggt gaccggacgc
    13561 tggacgtggt acgtcagaca tcgcgagatc gccagttaac actctggcag gcatgtcgtg
    13621 aactgttgca ggaaaaagcc ctcgccggac gtgctgccag cgccttacag cggtttatgg
    13681 agctgatcga cgccttagcg caggaaactg ccgatatgcc gctgcatgta cagactgacc
    13741 gggtaattaa agactccggc ctgcgcacca tgtacgagca ggagaagggc gaaaaaggtc
    13801 agacgcgtat cgaaaactta gaggaactgg tgacggcaac gcgccagttc agctacaacg
    13861 aagaagacga agatttaatg ccgctgcagg cattcctctc ccatgcggcg ctggaagcgg
    13921 gcgaggggca ggcggatacc tggcaggacg cggtgcagtt gatgacgcta cactcggcga
    13981 aaggtctgga attcccgcag gtgtttatcg ttggtatgga agagggcatg ttcccaagcc
    14041 agatgtcgct agatgaaggc gggcgtctgg aagaagaacg ccgtctggcc tacgttggcg
    14101 taacccgcgc gatgcagaaa ctgacgctga cctacgcgga aacccgccgt ctatatggca
    14161 aagaggttta ccatcgcccg tcgcgcttta tcggtgagtt gccggaagag tgtgtggaag
    14221 aggtgcgcct gcgcgccacg gtaagccgcc cggtcagcca tcagcgtatg gggacgccga
    14281 tggtcgagaa cgacagcggc tacaagctcg gccagcgcgt acgccacgct aagtttggtg
    14341 aaggcaccat cgtcaatatg gaaggcagcg gcgagcatag ccgtttgcag gtggcattcc
    14401 agggccaggg tattaaatgg ctggtggcgg cttacgcccg actggagacg gtgtaattta
    14461 cgattccgtt gccggatgcg gtgcgctaca ccgcatccgg catcagcacc ttacttagcg
    14521 cacttcttca catcaatatt ccagtcagca ccagacgcaa cctgatgttt ctgcgcgaaa
    14581 ttatccatat tcagcgccac ggaaacattc aataagctgt tcagatacac catcggctgg
    14641 ccttccggca catcgccgaa gcttgcgaca tacggcattt tccctgcgta tttttgctgg
    14701 gaaccttcgg aaatggtcac acacaacgtg tcgttgagtt tgattcctgc ctgattcagc
    14761 aactcgtcgc tgatattgct ccagacgttg ccgtactgaa tatcgagaat cgggatattg
    14821 cccttcactt caccttttgt tgctttggct ttctgataag aaagttcgac aacttttgca
    14881 ggaagctctg gccccacctg ctcgaacgtg atcgccccgg aagccagacg cgcaccggtg
    14941 taggcatata catcacgacc atggaaggta tatgactttt cggaaccttt cagacggttg
    15001 gttttttcat cgatttgccg gacgctctca atacccagcg attccgccac caacgtgagc
    15061 gtaccgttat ctggtgaaac gaagtactga ccgtttttgg ttttcagcac taccgattta
    15121 cggtctgtac caacacctgg atcgaccacg ctaacaaaca ccgaaccttg cggccagtaa
    15181 ctggcagtct gatacaggcg ataagcgcct tcccagatgt tatacggtgg aatttcgtgt
    15241 gttaaatcaa agattttaag attatggtca acaccgaatg cgaccccttt catcgccgag
    15301 acggcaccat ctttcaggct aaaatccgtt tgtaaaatca aagcgttatc cgcataagcg
    15361 gatgatgacc ccagacaggt taataaaaat aatgttgcga gcgttttttt catttttgtt
    15421 tcccttcatt tatctgatga ttttccagct gtgtagccag ccccagtttg tctggcctcc
    15481 tcgagtgtac aatgtttaac ctttctgctc gacggaaatc atggtgacaa aaggatagcg
    15541 ttgccacggg attgcctcgc ctttcatata catatgtgaa attgtgccat caagataaag
    15601 cagctgctca acgttcagtt tcgctttggc ataacaggca aaatcataaa aatttgtcgc
    15661 ctgctggctc agcaaaaaca cggcgttccc atgtttatta atcccaacac cgttacgaat
    15721 tttacgtgag gcgacgttgg gatgaatacg cggattaatt acaccgtttt ccatcaacaa
    15781 tggccctgac tgcaccgcaa actgaatctc tttactggtt ttaaaggcat ccagacgaac
    15841 gatgccgact ttatctcccg cgacataaaa cacgccgcca gggcgaataa agaaattccc
    15901 ttcacctgaa gcgagattta acgccacctt ctgctgaccg ttttcgatgt acaaaccgag
    15961 cggcgcatag ctttcatcat agatgccgcc gttcatcgcc atctgcacct gaccctgact
    16021 attaatatcc gccagcagcg catgtaacgt tccccacgct tcgccattgg ctttttgcca
    16081 gtacattttc acccgctctg tttgaggatt aacggtatac gcctgtacgg tcagcgtcgg
    16141 atctgagggt gcgcaatcat cagcggcaac agcaaacaag ggaagtaagg tgagggtgag
    16201 aaaaatccgt ttgagattca aggtgatcat tcctttacca atgaatagcc gatgcgccat
    16261 tataggccct gaatgtggga tttttttatc ctgttagcga ccttgacgag taccaaaaag
    16321 cgcgaagttc aactattgtt ctgtggtgtt ctgttgcgtg ttgacggcaa aattttgctg
    16381 gcgtaacatg cgcgcacgat cactctaaga ggacattcgc cttggacaca cccagtagat
    16441 actggctcac tatcctgtca tccaggatca actcctaagg ctatcccttt ttgctgatag
    16501 ccttagcggt tgtcagcgac ctcaattttt cccgtcgcgc tgagtcaggc tgtttaatgg
    16561 tctgaaaccc aatttgtttc tgtgtgccca ccgaactgtc cgatatttta agcattggga
    16621 gtcccggtca tgctgagcgc atttcaactg gaaaataacc gactgacccg gctggaagtc
    16681 gaagagtcac aaccccttgt aaatgcagta tggattgatc ttgtcgaacc ggacgacgac
    16741 gagcgactgc gcgtacaatc tgaacttggc cagagcctgg caacccgccc ggaactggaa
    16801 gacatcgaag catcggcacg tttctttgaa gacgatgacg gcctgcatat tcactccttc
    16861 ttcttctttg aagatgcgga agatcacgcc ggtaactcca ctgtggcatt taccatccgt
    16921 gatggtcgtc tgtttactct gcgtgagcgt gaactgcccg cttttcgtct gtatcgtatg
    16981 cgtgcccgta gccagtcaat ggtggacggt aacgcctacg agctgctgct ggatctgttc
    17041 gaaaccaaaa tcgaacagtt ggcagatgaa attgaaaata tctacagcga cctggagcag
    17101 ttgagccggg taattatgga agggcatcag ggcgatgagt acgacgaggc gctctccacg
    17161 ctggcggaac tggaagatat cggctggaaa gttcgcctgt gtctgatgga tacccagcgc
    17221 gcgctcaact tcctggtacg taaagcacgc ttaccgggtg ggcaactgga gcaggcgcgt
    17281 gaaatcctgc gagatatcga atccctgctg ccgcataacg aatccctgtt ccagaaggtg
    17341 aacttcctga tgcaggcggc gatgggcttt atcaatatcg agcagaaccg catcatcaaa
    17401 atcttctcgg tggtatccgt ggtgttcctg ccaccgacgc tggtcgcttc cagctacggg
    17461 atgaactttg agtttatgcc ggaactgaag tggagcttcg gctacccagg cgcgattatc
    17521 tttatgatcc tcgcgggcct ggcaccgtat ctgtacttta agcggaagaa ctggctgtaa
    17581 aaaacgagaa cggtggctta gcctggctaa gccaccgatt atttaaaggc tccaggtatg
    17641 aatacctttt acttcttttt catagaacca tctgttggta ttgtatgaaa cataagcggc
    17701 gataatgaat ccaaatacat tatagccaat catgtaacca aaaattaaag aaaatatcgc
    17761 caggaataga acaacaatag ccttcttcca taaacccaat acaaataaat agacccacga
    17821 gaagaaaaaa gcaataacat ttgttctaat tattatcttt tgccttgtgt ttaatccttt
    17881 taatgcttgt ttatattctg ggcttgcacc ccaaaatcca gggaagccat gttcatcata
    17941 aaacgaaaag cggtacttcc acttttcagt taatgagcca tctgccatat aatccttact
    18001 cataaaatct ccattaatta tttacggggg gaatcagtgg gggcaagaac taacatgcca
    18061 aaggtggaaa aataacaaat caaaaaaatc atcgaaccat tgccagaaca gtcaaaatgc
    18121 tcagcaacca tgatgatgaa agaaatgata tagactacta atgtactaaa aatataagtt
    18181 tttatataag taaaaccact atcccggagt cgttggcaat tcatgttgat aacgagataa
    18241 tgtaaaagaa tggtagatgt tataacaaag aaaccagccc cggcattgga aaaaaaagaa
    18301 ataagtaaga tacaaatt
//
LOCUS       DAFGPF010000097        18132 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFGPF010000097 DAFGPF010000000
VERSION     DAFGPF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18132
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.097"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..174
                     /locus_tag="LSX49_003750"
     CDS             <1..174
                     /locus_tag="LSX49_003750"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708237.1"
                     /note="catalyzes the formation of pyruvate from serine;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine dehydratase"
                     /protein_id="HBL7170108.1"
                     /translation="SALAGMAGPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMV
                     PEEEMNQYLAKGR"
     gene            complement(282..1820)
                     /gene="emrY"
                     /locus_tag="LSX49_003751"
     CDS             complement(282..1820)
                     /gene="emrY"
                     /locus_tag="LSX49_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HBL7170109.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDLDWFNSSTIILLTVVSVISLISLVIWESTSENPILDLSLFKSRNFTI
                     GIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNK
                     IDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFS
                     GLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSS
                     SQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTA
                     KGVG"
     gene            complement(1820..2983)
                     /gene="emrK"
                     /locus_tag="LSX49_003752"
     CDS             complement(1820..2983)
                     /gene="emrK"
                     /locus_tag="LSX49_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HBL7170110.1"
                     /translation="MEQINSNKKHSDRRKYFALLAVVLFIALSGAYAYWSMELKDMIS
                     TDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKAKNNLA
                     NIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKEALEHTKDTL
                     ISSKAALNAAIQAYKANKALVMNTPLNRQPQVIEAADATKEAWLALKRTDIKSPVTGY
                     IAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGENV
                     VFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEHPLRIGLSM
                     TATIDTKNEDIAEMPDLASTVTSMPAYTSKALVIDTSPIEKEISNIISHNGQL"
     gene            3399..4013
                     /gene="evgA"
                     /locus_tag="LSX49_003753"
     CDS             3399..4013
                     /gene="evgA"
                     /locus_tag="LSX49_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HBL7170111.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            4018..7611
                     /gene="evgS"
                     /locus_tag="LSX49_003754"
     CDS             4018..7611
                     /gene="evgS"
                     /locus_tag="LSX49_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HBL7170112.1"
                     /translation="MKFLPYIFLLCCGLWSTISFADGDYIEYRGISSNNRVTLDPLRL
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRIRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALEDGEVDIVLSHLVASPPLNDDIAATNPLIITFPALVTTLHDSMRPLT
                     SSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFLLTRKDSIVLNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDETGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLNPGGWDILPAAIYSEDRENNVSFAEVFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIKVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVQNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     ESPFKDVFSNTHEVTAETKENRKIYTQVFEIDNGIEKRCINHWHTLCNLPASEHAVYI
                     CGWQDITETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGS
                     GLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHS
                     FAAIAASKSIALSCSSTLPERYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLG
                     HIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNM
                     QGDLSLESHPGIGTIFTITIPVEITQQVAAVEAKAEQPITLPEKLSILIADDHPTNRL
                     LLKRQLNLLGYDVDEATDGVQALHKISMQHYDLLITDVNMPNMDGFELTRKLREQNSS
                     LPIWGLTANAQANEREKGLNCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDI
                     EALKNNTANDLQLMQEILMTFQHETHKDLPAAFHALEAGDNRTFHQCIHRIHGAANIL
                     NLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEITVFCQQND"
     gene            complement(7667..8812)
                     /gene="yfdE"
                     /locus_tag="LSX49_003755"
     CDS             complement(7667..8812)
                     /gene="yfdE"
                     /locus_tag="LSX49_003755"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HBL7170113.1"
                     /translation="MTNNECKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPR
                     FSSNILRVHNQAILKEYIERTLKTQVAEVWLARIHEVGVPVAPLLSVAEAINLPQTQA
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(8886..9830)
                     /gene="yfdV"
                     /locus_tag="LSX49_003756"
     CDS             complement(8886..9830)
                     /gene="yfdV"
                     /locus_tag="LSX49_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HBL7170114.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            complement(9900..11594)
                     /gene="oxc"
                     /locus_tag="LSX49_003757"
     CDS             complement(9900..11594)
                     /gene="oxc"
                     /locus_tag="LSX49_003757"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HBL7170115.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIIL
                     GKGAAYSQSDEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            complement(11648..12898)
                     /gene="frc"
                     /locus_tag="LSX49_003758"
     CDS             complement(11648..12898)
                     /gene="frc"
                     /locus_tag="LSX49_003758"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HBL7170116.1"
                     /translation="MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDV
                     TRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAI
                     DHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
                     LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRL
                     DKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQN
                     WENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIP
                     CAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEH
                     TAAVLQELGYSDDEIAAMKQNHAI"
     gene            complement(13410..14042)
                     /locus_tag="LSX49_003759"
     CDS             complement(13410..14042)
                     /locus_tag="LSX49_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HBL7170117.1"
                     /translation="MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVKQTQKTAA
                     AERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKKT
                     NVNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVME
                     NQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
     gene            14337..14612
                     /locus_tag="LSX49_003760"
     CDS             14337..14612
                     /locus_tag="LSX49_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL7170118.1"
                     /translation="MKVNLMLFSLFLFVSIMACNVFAFSISGGGSEASYKETEKTSVM
                     TTTHSTKLQPSQAILFKMREDAPPLNLTEDITPTYPTKANYLIHPLR"
     gene            complement(14689..14931)
                     /locus_tag="LSX49_003761"
     CDS             complement(14689..14931)
                     /locus_tag="LSX49_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HBL7170119.1"
                     /translation="MIYLWMFLALCIVCVSGYIGQVLNMVSAISSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            15284..16204
                     /gene="lpxP"
                     /locus_tag="LSX49_003762"
     CDS             15284..16204
                     /gene="lpxP"
                     /locus_tag="LSX49_003762"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HBL7170120.1"
                     /translation="MFPKCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GTMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVSALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLYITPEMEGYPTDENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            16561..16632
                     /gene="ypdK"
                     /locus_tag="LSX49_003763"
     CDS             16561..16632
                     /gene="ypdK"
                     /locus_tag="LSX49_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HBL7170121.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(16697..17935)
                     /gene="alaC"
                     /locus_tag="LSX49_003764"
     CDS             complement(16697..17935)
                     /gene="alaC"
                     /locus_tag="LSX49_003764"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HBL7170122.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
BASE COUNT         5216 a         4164 c         3807 g         4945 t
ORIGIN      
        1 tcggcactgg cgggtatggc cggacctcag cgcgtgtgcg catcagtaag ttaccaacag
       61 atgcacggtt tcagcgcaga acaactgcgt aatgccactc atctggtgtg ggcgacggga
      121 ggtggaatgg tgccggaaga agagatgaat caatatctgg caaaaggccg ttaataacgt
      181 ttcaacgcag catcaccatc ctttccctgg gtgagcgatg ctgccgatga cgcagactta
      241 agattctgcc gttttacctg ctatagcctc ctctttttcc atcacccaac gcctttcgct
      301 gtaaacggcg gtttcgcaaa ccaaaccaaa accgtaagta agataaaagc aatagccgcc
      361 atacggaaaa tctcatttgc agaaatagaa agtgactgct gagttatttc attattaatt
      421 tcattaagaa ctcctgaaag cgaaccatag tatttatcca taatttgtga cgatgaatta
      481 aacacggggt taaattgatc gatggttgct gtcaactgac tatggtgtaa cgattcgcgg
      541 cgtccccaca gtgtcattgt caacgacgta ccaactgatc ctgacaaggt gcgaaaaaaa
      601 ttactcatac tcgaggcatt ggcaaattta ttatctggca agcctgaaaa cgaaatcgtt
      661 gttaagggta aaaagaaaca ggcaacggcg aatccctgaa aaaactgtgg caaaatgatg
      721 cctgtaaaat caatcgttgg cataaatgtc acagaacgcc agtaatagca aaccgcatac
      781 atcaaaaaac taaatgtcac caacaaccgc atatcaattt tgttgccata acgtcctatc
      841 aaaggtgata ttaatagcgg catgataccg atgggcgcat aggcaagtcc ggcccatatc
      901 gcattatacc ccatcgtttc ctggagtaac tgcggcataa gaactatcgc tccagagtaa
      961 aataaatacg cgcatgtgat actcacaata ccaatggtga aattacggga cttaaacaaa
     1021 ctgaggtcaa gaatcggatt ctctgaggtc gactcccaaa tgactaaaga gatcagagaa
     1081 ataactgata ctactgttag tagtattatt gtactcgagt tgaaccaatc cagatcgcgc
     1141 cctttatcaa gcataatttg caagccacca acaccgagca ctaacagggt cagtcctggt
     1201 agattcattt tgaccggtga agtctcagtt tctcgtcctt taagtaaggt taagcataat
     1261 gtcaggacga taatccccat agggacattg attaaaaata tccaacccca gctaaagtta
     1321 tcgcaaatat agccgcccaa tatcggccca catatcggag cgataatcac ggtcattgac
     1381 cataatgcca gagcaaatgt tcttttttct ggtggataat tccttaataa taaactctgt
     1441 gacagtggaa ttaacggccc cgccattaac ccctgaacga ctctaaaaaa tatcagcaca
     1501 tcaagattgg tcgataaact acacattaat gaagacagcg aaaaaaaggt tactgaaagt
     1561 aaaaataacc ttaattcgcc tattctttgt gccagcctgc cggtaacagg gatcgcaatg
     1621 gcatttgcta cgccaaacga ggtgataacc caggtacctt cgtctgttga tgctcccaga
     1681 aagccagata ttgtcggtat tgcgacgtta gaaatagtgg aatccaacat ttgcataaac
     1741 gtcgctaatg acaatgcaat agtgacgcac cataacgtcc caccggttaa tggtgcagga
     1801 gttgatttag tgattgccat taaagttgtc cattatgcga aataatgttg ctaatttctt
     1861 tttctatcgg actggtatcg ataactaaag ccttactggt ataagcaggc atggacgtca
     1921 cggttgaagc cagatcgggc atctcggcaa tgtcttcatt cttcgtatca atagttgcag
     1981 tcatcgataa accaatgcgc aaagggtgtt ccatgagttc ttttggatcc agagaaactt
     2041 caaccggtac acgctgaacg attttgatcc agttccctgt cgcattttgt gcaggtaata
     2101 aggagaacgc attgccggtt cccatattga tccctgtcac ccgaccatga aacacaacat
     2161 tttcaccata aagatcgctg ataatattga ccgattgacc aatccgtaca tccgtgagtt
     2221 gtgtttcttt aaagttggca ttaacccaca tttgacgcgc cggtacgaca gccattaacg
     2281 attgtccggg actcactgtt tcgccgacct gaacacttct ctgggcaata taaccggtaa
     2341 ccggactctt aatatccgta cgtttaagcg ccaaccaggc ttctttggtt gcatctgcag
     2401 cttcaatgac ttgtggctga cggtttaatg gtgtgttcat tactaaagct ttattcgctt
     2461 tataagcctg gatagcagca ttcaatgccg ctttgctact tattaacgta tctttggtat
     2521 gctccagcgc ttcttttgaa ataacccctt gcttcgctaa aggcacacga cggttataat
     2581 cttctaaaga ttgttgatac tgaatacgtg ctgaagcgac ttcggcactg tattgtttat
     2641 cctgtaagta tagtttattc gtttgccgaa caatatttgc cagattattt ttagctttat
     2701 tgagtgcgat agtggcatca gttttatcca gtgaaactaa aatgtcacct tgtcgaacgt
     2761 agttcgtatc tttatgatta acgacagtga cactgcctga gacttgtgca gaaattggat
     2821 ctgcatttcc cgtgacatag gcgtcatctg tactaatcat gtcttttaat tccattgacc
     2881 aataggcata ggcacctgaa agcgcaataa ataaaactac cgctaacaaa gcaaaatatt
     2941 ttcttctgtc agaatgtttt ttatttgaat taatctgttc cactattatc tctcatttcg
     3001 catagatgaa atttatgaat tgaatgaaaa gagtattcat tcctcatatc aaacacagtg
     3061 catgttttgc acattatccc aggaacgttg gagggctaat ttaaatgagg tgcaaaaaaa
     3121 acaacagagg actaaaccgc ggcttttgca atacaattct tacgcctgta ggattagtga
     3181 gaaaacttat agtgctcatt tgaaactata aatcatcggt atcatccctg attttattgt
     3241 tgacatttta tttatgccga ctatttatat ggtatacttg tcgaattatc ttaaaggaag
     3301 ctcaaatttt cttattttta ttgagaaaat gagatgatac cttatgtctg tattactaca
     3361 gggagaaggg aaatgcttca ttgcaaaggg aataatctat gaacgcaata attattgatg
     3421 accatcctct tgctatcgca gcaattcgta atttattgat caaaaacgat attgaaatct
     3481 tagcagagtt gactgaaggc ggaagcgccg ttcagcgggt ggaaacactt aagcctgata
     3541 tcgtcatcat tgatgtcgat atccccggag ttaacggtat ccaggtgtta gaaacgctga
     3601 gaaagcgcca atatagcgga attattatta ttgtctccgc taaaaatgac catttttacg
     3661 ggaaacattg tgctgatgct ggcgctaatg gtttcgtgag taaaaaagaa ggcatgaaca
     3721 atatcattgc agctattgaa gctgcaaaaa atggctactg ctatttcccc ttctctctca
     3781 accggtttgt tggaagttta acgtccgacc agcaaaaact cgactcctta tcgaaacaag
     3841 aaattagtgt catgcggtat attcttgatg gcaaggataa taatgacatt gctgaaaaaa
     3901 tgttcatcag caacaaaact gtcagcactt ataaaagtcg cttgatggaa aaattagaat
     3961 gcaaatcact gatggatctt tacacattcg cacaacgtaa caaaatcggc taaccacatg
     4021 aagtttttac cctatatttt tcttctctgt tgtggtcttt ggtcgaccat aagtttcgca
     4081 gacggagatt acatcgaata tcgtggcatc agtagtaaca accgtgtcac acttgatcca
     4141 ctacgtctga gcaacaagga attacgttgg ctagcgagca aaaaaaatct tgtgattgca
     4201 gtacacaagt cccaaacagc tacgttgttg cataccgatt cgcagcaacg gattcgtggt
     4261 attaatgctg attatttaaa tcttttaaaa agagcgttaa atatcaaatt aacactccgg
     4321 gaatacgcag atcatcaaaa agcaatggac gcgctggaag acggtgaagt tgatatagtg
     4381 ttatcacatt tagttgcttc gccgcctctt aatgatgaca ttgctgcaac taatcctctg
     4441 ataattacct ttccggcgct ggtcactacc cttcacgatt caatgcgacc gcttacctca
     4501 tcaaaaccag taaatattgc tcgagtagca aattatcccc cagacgaggt aattcatcaa
     4561 tcatttccaa aagcaacaat tatctctttt acaaatttat atcaggcatt agcatccgtc
     4621 tcagccggac agaatgatta ctttattggt agtaacatca ttaccagcag tatgatttcc
     4681 cgttatttta ctcactcctt aaatgtagtg aagtattata actcaccgcg tcaatataac
     4741 tttttattaa ccagaaaaga ttcaatcgtt cttaatgaag tactcaatcg atttgttgat
     4801 gctttaacaa atgaagttcg ctatgaagta tcacaaaatt ggcttgatac aggaaacctg
     4861 gcctttctga acaaaccatt agaactcact gaacatgaaa aacagtggat taagcagcat
     4921 cccgatttaa aggtgctgga aaatccttac tcgccaccct attctatgac agatgaaact
     4981 ggctcagttc ggggcgtgat gggtgatatt cttaatatta ttaccttgca aacaggttta
     5041 aatttttctc cgatcaccgt ttcacacaat attcatgctg ggacacagct taaccccggt
     5101 ggatgggata tattgcccgc cgctatttat agtgaagatc gagaaaataa tgtttcattt
     5161 gctgaagtct tcataacaac gccttacgtt tttgtcatgc aaaaagcgcc tgacagtgaa
     5221 caaacattaa aaaaaggaat gaaagttgcc attccatatt attatgagct tcattcgcaa
     5281 ttaaaagaga tgtatccgga ggtagagtgg ataaaagtcg ataacgccag cgctgcattt
     5341 cacaaggtca aggaaggtga acttgatgct ctggtcgcga cacagttaaa ttcgcgttac
     5401 atgatcgacc attactatcc taatgaactt tatcattttc ttattcccgg cgttcagaat
     5461 gcatcacttt cgttcgcttt tcctcgcgga gaaccggaac ttaaggatat tattaataaa
     5521 gcactgaatg caattccccc aagcgaagtt ctgcgcctga ccgaaaaatg gattaaaatg
     5581 cccaatgtga ccattgacac atgggacctc tatagcgagc aattttatat tgttacgaca
     5641 ttatccgttt tattagttgg cagtagcctt ttatggggat tctacctgtt acgctcagtt
     5701 cgtcgtcgta aagttattca gggtgattta gaaaaccaaa tatcattccg gaaagcgctc
     5761 tcggattcct tacctaatcc aacttatgtt gtaaactggc aaggtaatgt cattagtcac
     5821 aatagtgcat ttgaacatta tttcactgct gattactata aaaatgcaat gttaccatta
     5881 gaaaacagtg aatccccctt taaagatgtt ttttctaata cgcatgaagt cacagcagaa
     5941 acgaaagaaa accgaaaaat atacacacag gtatttgaaa ttgataatgg catcgagaaa
     6001 agatgcatta atcactggca taccttatgt aatctgccag caagcgaaca tgctgtttat
     6061 atttgtggtt ggcaagatat taccgagacg cgtgatttaa ttcatgcact cgaagtagag
     6121 agaaataaag cgatcaatgc aactgtcgca aaaagccagt ttctggcaac aatgagtcac
     6181 gaaataagaa caccaataag ctccattatg ggcttcctgg aacttctgtc gggttctggt
     6241 cttagcaagg aacaacgggt ggaggcgatt tcacttgcct acgccaccgg acaatcactc
     6301 ctcggcttaa ttggtgaaat ccttgatgtc gacaaaattg aatcgggtaa ctatcaactt
     6361 caaccacaat gggtcgatat ccctacttta gtccagaaca cttgtcactc tttcgctgcg
     6421 attgctgcaa gcaaatcgat cgcattaagt tgcagcagta cgcttcctga acgctacctg
     6481 gttaagatcg accctcaggc gtttaagcag gtcttatcta atttactgag taatgctctc
     6541 aaatttacta ccgagggggc agtaaaaatt acgacctccc tgggtcacat tgatgacaac
     6601 cacgctgtta tcaaaatgac gattatggat tctggaagtg gattatcgca ggaagaacaa
     6661 caacaactgt ttaaacgcta tagccaaaca agtgcaggtc gtcagcaaac aggttctggt
     6721 ttaggcttaa tgatctgcaa agaattaatt aaaaacatgc agggcgattt gtcattagaa
     6781 agtcatccag gcataggaac gatatttacg atcacaatcc cggtagaaat tacccaacaa
     6841 gtggcggctg tcgaggcaaa agcagaacaa cctataacac tacctgaaaa gttgagcata
     6901 ttaatcgcgg atgatcatcc gaccaacagg ctattactca aacgccagct aaatctatta
     6961 ggatatgatg ttgatgaagc cactgatggt gtgcaagcgc tacacaaaat cagtatgcaa
     7021 cattatgatc tgcttattac tgacgttaat atgccgaata tggatggttt tgagttgact
     7081 cgcaaactcc gtgagcaaaa ttcttcctta cccatctggg ggcttacagc caacgcacag
     7141 gctaacgaac gtgaaaaagg gttaaattgc ggcatgaact tatgtttgtt caaaccgttg
     7201 actctggatg tactgaaaac acatttaagt cagttacacc aggttgcgca tattgcacct
     7261 cagtatcgcc accttgatat cgaggccctg aagaataata cggcgaatga tctacaactg
     7321 atgcaggaga ttctcatgac tttccagcat gaaacgcata aagatctacc cgctgcgttt
     7381 catgcactag aagctggcga taacagaact ttccatcagt gtattcatcg catccacggt
     7441 gcggctaaca tcctgaattt gcaaaagttg attaatatta gccaccagtt agaaataaca
     7501 cctgtttcag atgacagtaa gcctgaaatt cttcagttgc tgaactctgt aaaagaacac
     7561 attgcagagc tggaccagga gattactgtt ttctgtcagc aaaatgacta aatagcggct
     7621 cccacaatgt tcaaatgtgg gagctattta ccagcacatc ttacatttat gatgagaact
     7681 cctggcgaat ttgttcccca tgctggtcga gcgttgccgc tcccggcata acatgcgggt
     7741 ccgcgcagcc gctgattttt atcggattac ccggcatcat tattcccccg gcttcaatca
     7801 acatatttct cgcctgagtt tgtggtaaat taatggcctc agccacactt aataacggcg
     7861 cgacgggcac accaacttca tgtattctgg ctaaccaaac ttcagctacc tgcgttttta
     7921 acgtccgctc aatatattct ttaagaatag cctggttatg tacgcgtaaa atattgctgc
     7981 taaatcgggg atcattaacc agttccgtaa gctccagtgc ctggcataac gcagaaaaaa
     8041 gcttgtcatt accacaacaa atcgtaatcg gcttatcctg agtatcgaaa acatcaaaag
     8101 gtgccatgta gggatggcga tttcccaggc gttgtggtga cttcccagtc gcgatatatg
     8161 ccatcagtcc atgctccaga aaactcagag tggcatcaaa catcgctata tcgacatgcg
     8221 cccctctctg gctcttttcg cggccataaa gtgcactcac tattccactg aataaataaa
     8281 caccgccaca gagatccgca agagaggtac caacgcgcac tggcggagca tcagggtatc
     8341 ctgtttccat cattatcccg ctcattgcct gaatgatggt atcgtaggca ggagcatctt
     8401 ttagcggacc ggtatgtccg aaacctgacg atgaagcata tataaggcgc gggttgattt
     8461 cttgtaacct ttcccatgaa aacccgagtt tttccattgt acctgggcga aaattctcag
     8521 ctaatacatc agcttgttta agcatattta taaatatact tttatcgtga tcattcttta
     8581 aatcaagaac cacactctct ttgccatgat taataaaact gtaatagagt gactgtccat
     8641 ccacataggg accaaatgtg cgggtatcat caccatgacc cggtggctca actttaatta
     8701 cccttgcgcc catattacaa agaagttgag ttccgaaagg cccattaagg acatgcgtca
     8761 tatcgataac taataagcct tcaaacggcc ctttgcattc attatttgtc atttgcttat
     8821 gccttgaaaa aagccgaagg tgaaaagaca cttcggcatt tatgtaaaat caataacatg
     8881 ataaattatg aaaccagtcg actgacataa atccacaaag gagccgtgac gacaaaaccc
     8941 agtacgctca cagccaatga cgctgtacca gtacgggtgt agacattaaa ccggctggca
     9001 ataatgattc cggagaatgc cggcggtaat gcgcctgcca gtaccatcat ctgcaaatgt
     9061 tcgctattca aatgacatgc cataccgacg agaagcagcg ccagtggcat cagaatcagc
     9121 ttcaggaaag tgttataagc aatttcggca ctgaactcga atttatgtgc agccagagtc
     9181 aaccccgcag cgaataccgc tacccctgag ttagccttcg caatcagatt aaaggttggg
     9241 tcccatgctg ccggaatttt taccccaacc agcaccagga tcgttgccag aacaggtgcc
     9301 catactactg gctcctttgc cgcagaaatt aatgcgctca gattactatt cttcttacca
     9361 tccgctcctg aggaaggatt cagcaaatac agaccaatag gaatagtaat tgcgttaaca
     9421 ataatagaaa taattgctac cactaaacct gttgatacgg aatcaccata aataggatcg
     9481 agaactgcaa accccaggaa tccaatggta ggtgaacctg caattaatgc acatactgct
     9541 gcttctgcat gggtacgttt aaaaaatttg tagcaaccga accaggagaa aaagaaacat
     9601 ccgacaataa ccacaagtga tacaagggtc aggcgagtgt ccgcaaaaat catttccctg
     9661 tttgccctgg taatagaaac aaatagagcc gcaggaagag cgtagtttaa taccagttta
     9721 ttaaatgccc gggcttgatc ttctgaaaaa gtttctcgtc tgccgctaaa ataacccaac
     9781 agcatgatta cgataatagg caataaatcg ccaataaaaa atgttagcat aatagtattt
     9841 ccgataaggg tcccctcacc atcgcataat aagttggcaa gaggagacga tgtcagtatt
     9901 taattaccag cgacttgttt tgggttaagt ttggtaatat ggccactttc agttcctgct
     9961 gctgggtcga tgaccacatt aataatggtc ggtttgcgcg actgaattcc ggtggttaaa
    10021 gcatgacgaa gttcatctgt cgtggtgacg ttatagccaa cgccacgaaa cgcatccatt
    10081 aatttgtcat accttgcatg gtgcaacaga tccgttggcg atggtgcacc agcgccgctg
    10141 aggtcaacac cgtctcctct gtagatgccg ccattattaa aaataacgat cgtcaccggc
    10201 aggttatatc gacaaatcgt ttcaatctcc atcccactga aaccaaaagc actatcacct
    10261 tcaatagcga caaccggaga accagaggtc acgctagcac cgatggcata gcccataccg
    10321 atgcccatga caccccaggt gccacaatcc agacgacgac gtggtttata catatcaata
    10381 atatttcgtg cattatccag ggtatttgcc ccttcattaa ctaaataaat atcctggttc
    10441 tcgcgcaaaa catcgcgcac ggcactcaat gcattaaagt aatttaatgg ttgggtatct
    10501 gtacttaact tttcatgcat tttttgtgca ttttgctgct tgtggatatt taaaatatca
    10561 cgccacacca gtggagtcgt aaatgtgttt tgtttcaatt ctgccagcat accttgcata
    10621 ctggatgcaa tatcgccaac gactggcaca gcaatggggc ggttgctgtc aatttcctgc
    10681 ggttcaatat ccagttgaat aaactgtgta tctgccgccc atcctttttt accgtgtgcc
    10741 agtaaccaat tcagtcgtgc accaacaagc atgacaacgt cagcatttgc cagggcaaac
    10801 gaacgcgcag ctgccgcaga gagtggatgc gtatcttcga ggatcccttt cgccatagac
    10861 attggcagga atggaatctg ggcactttca ataaattcac gaagctgttc atcagattgt
    10921 gaatacgccg cgcctttgcc aagaataatt aatggtcgtt cagcttttgc taaaagcgaa
    10981 attgcgctag tgactgactt cgggcatggc aataatgctg gcgacggatt ttcaacttta
    11041 acaatcgtgg ttaacgcttc gtctttttcc atcgtcgcgg ccaggacatt tgctggcaaa
    11101 tcaagataaa caccgccagg acgacccgat actgagaccc ggatagcgcg tgccaatgca
    11161 atgccaagat cctgcggctg attaacgcga aatgctgctt tggcatacgg ttttgccgca
    11221 ttcatttggt ccagctcttc ataatcacct tgctggagat cgacgatcgc gcggtcgctg
    11281 gagccgctaa tcatgatcat cggaaaacca tttaccgttg cattggccaa tgcggtcaaa
    11341 ccgttgagga atcctggcgc agacactgtc aggcagatcc ctggtttttg ggtaagaaaa
    11401 ccgcttgctg cagcggcata acctgccgac tgctcatgac gaaaaccaat ataacgaatg
    11461 ccttccgcct gggcatggcg cgccatatcc gtcacaggaa tacctacaac accataaata
    11521 gtgtcaatat tattctgttt taatgcttca acgatgatat gcataccatc tgtcatttga
    11581 agttgatctg acatgattaa taacctcgaa atttttataa attgggagcc agaagccccc
    11641 gttaatatca gatggcgtgg ttttgcttca ttgcagcaat ttcatcgtcg ctataaccca
    11701 gctcctgcaa tacagcagcg gtatgttcac ctaatagcgg cgcagcttta atatccggcg
    11761 taaaggcaga gaatttcatt ggacaaccaa ctgtcagata ttttccacgc aacggttgtt
    11821 ccacttcgac aacactgcca ctttggcgca aagagggatc aagtgaaatt tctttcatac
    11881 ttaaaaccgg tgcgcaagga atatcaaact gagtcaaata ggccacagct tcatgtttat
    11941 caatagtgac agtgtatttt tcgatttcag caaaaatatc gaaaatatgt ggctgtcggg
    12001 catgggctgt actgtatgcc ggatcggtaa tccattctgg tttgccgatg gctttacagg
    12061 tgttttccca gttttgctcc tgaatagtga aataaatata ggcgttagga tcggtttccc
    12121 agcctttaca tttcaggatc cagccaggct gaccaccacc acccgcatta ccaccgcggg
    12181 gaactgcatc accaaatgtg ccattcggat actgcgggta ttcttccaga taacccaatt
    12241 tatcgagacg ctgctggtcg cgtaatttca cgcggcaaag gttcaacacg gcatcctgca
    12301 ttgacatggt cactcgttgc ccacgccccg ttttttcgcg atgcagcaaa gcagcaagta
    12361 aaccgatcag caaatgcatt ccggtgttgc tgtcacccaa cgctgcagcg cttaccagcg
    12421 gcggaccgtc ccaaaaacct gtagtagatg ccgcgccacc cgctgcctga gcaacgtttt
    12481 cataggcttt tacattcaca taaggcgaac actcatcaaa ccctttgatc gaaccaaaaa
    12541 tcagacgtgg attgatttct tgaatatgct cccaggtgaa gcccatatga tcaatggccc
    12601 ctggatgaaa gttctcgact aagatatcag cttcgcggat cagcttttcc attacctctt
    12661 tgccttccgc tgttttggta tttaattcaa tagaacgttt gttactgtta agcatggtga
    12721 agtaaagcgc atcgatatca ggaatatctc gcagctggtg gcgcgttacg tcaccaacgc
    12781 cgggacgttc aattttaatg acgtcagcgc caaaccaggc cagcatttga gtacaagatg
    12841 ggccagattg cacaccggtg aaatcgagaa ctttaattcc ttgaagtgga gttgacatag
    12901 caatacctat tagttaatta aatatgtgtt aatttagcgt ttatttaagg cataacgcct
    12961 ctataaataa tctgcaaaat atcgtcgtag ctgcactcga tatttttaaa ttcctgtatc
    13021 aagtgctgaa aatcatttca tcgctacttc caattccttt ctgcatggta agtagtgagg
    13081 acgaaaagaa gaatataata aatattggtt cgcggtaatc agagagagcc gcgacatttg
    13141 tgatgttatt cttacaactg taagaagtgt cagtgattta caagtaaggt tatgattaca
    13201 ctatttaaag cgtaccataa aatataacat aataaatgat ttgtgataat atgggattat
    13261 tgcggtttac tttgaggaag ataaaatgcg agtatataga accgcgagcg ccaaataatt
    13321 ttatgaccac aacctgtcgt attgtggtca taaaaaattg tcggctggag ggagttaaat
    13381 cctttacctc aatatattgc ctgtcaggtt tagttcacaa acagtgcttc gctatcaacg
    13441 atgattccat cttccgcacc tttaagcgcc aggtttgcct cgtagtattg ctttttatca
    13501 agcagtttct gcgcatcagc aagtgcatta cgagtctgtt tgagcggcat cagatattgg
    13561 ttttccatta cgccaacacc ggccaggcgc agctcttcca ttgcgccctt tttatcccct
    13621 ttcgccattt tttcgttggc aatttttatc gcggcttctt tttcgggtgt cgctacataa
    13681 ctctcagaaa ttccgacaga tgcattaatg acaatatatt ggtcatcatt gacgttggtc
    13741 tttttacctg gcttagcgaa ctttgcccat tcggtactat catctgacag caaagcggaa
    13801 gcttcattgg tcagttcttt tgccttttct ggatcgccat gaaacagagc caggcgcgct
    13861 acctgcacgt cacgcatcgc atataaacct tgttcagaga tacgctctgc tgctgccgtt
    13921 ttctgggttt gcttaacttg ctgagtttgc tgttgtgccg ctaccggtgc attatcagca
    13981 gcccatacag ttgaagatgc cagaattgct gtgaccatcg tagccataat taaacgtttc
    14041 atacttacct cattctttaa cagttttaga aaacgccgcc atcatattgg gtgagcatga
    14101 aatgagaaat cagagagcaa cggtcatttt gaaagggtta tcttacaact gtagttatta
    14161 tcgcaaagcc gcttttagtc ttacagttgt aggaatctgc ttcctgtcgc agagaactat
    14221 tcttatatac cacaaagata tgtcatttat tatatcgatg taaatactga ttaattaaat
    14281 ataaatacag ccataacatc gtaggttttc agtgaaccat ttccaggata ttttctatga
    14341 aagtaaactt aatgcttttt agcttatttt tatttgtctc tattatggca tgcaatgttt
    14401 ttgcattttc tatttctggt ggtggtagtg aggcgagcta taaagagaca gaaaaaacgt
    14461 cagtgatgac gacaacgcat tctacaaaac ttcagccatc acaggcgatt ttgtttaaga
    14521 tgagagaaga tgcaccacca ttaaacctca cagaagacat cacgcctact tatccgacaa
    14581 aggcgaatta tctcattcat cctttgcgat agcgtctgtc acctggcagg tgaacaatca
    14641 tgtctgatgc tgatgtgaac acctgcccaa atgagccatc ctgacccact atcgcctgcc
    14701 ataccccacc ataaagcgaa tcatcaagcc acaagccggg gcaagaaaca taaatatccc
    14761 cgtcaccagt tcattaccgc cagttaacca catggtgaag taataaatga gtgcagcgag
    14821 gatcaccatg ccgaagaaag aagagatcgc cgataccatg ttcagtacct gaccgatgta
    14881 tccgcttacg cagacaatac acagggcgag aaacatccat aaataaatca tagctcaacc
    14941 tcctgccgcg ctaaaaaacc tgtaacttca gtcactttaa tagtaagaca atccttaacc
    15001 tctggcaatt tttgctaagc atcaatcaaa acagcatgtt aaatgcaaga ctgttacgta
    15061 cggaaaaata tttactttgc acgattaata atcagtagct gaaagcagtc agcgagtgat
    15121 aaagtacaga taccgcattc atgctcctcg tggttatgtc ctgactagtc tttacactct
    15181 ttacaggaac cattgtcgta catgatggcc taatcaattg agtgtaccgc tgtcgacatg
    15241 gaatcttctg cgatacaaca attcgtatct acagaaggta actatgtttc caaaatgcaa
    15301 attttcccgc gagtttctgc atcctcgcta ctggctcacg tggtttgggc ttggtgtact
    15361 ctggctttgg gtacagcttc cttatcctgt tctctgcttt ctcggcacgc gtatcggcac
    15421 aatggcgcga ccattcctga aacgtcgtga atctatcgcc cgtaaaaacc tggaactttg
    15481 tttcccgcag cattctgcgg aagagcgcga gaagatgatt gccgaaaact ttcgttcact
    15541 cggcatggcg ctggtagaaa ccggcatggc gtggttctgg cccgacagtc gcgtacgtaa
    15601 atggtttgat gtggaagggc tggataacct taaacgcgca caaatgcaaa atcgcggcgt
    15661 aatggttgtc ggcgtccatt ttatgtcgct ggaactgggc ggtcgggtga tgggactttg
    15721 ccaaccaatg atggccacct atcgcccgca taataatcag ctgatggaat gggtccagac
    15781 ccgtggtcgc atgcgctcta acaaagcgat gatcggcaga aataatctgc gcggcattgt
    15841 cagtgcactg aagaaaggtg aagcggtatg gtttgctccc gatcaggatt atggtcgtaa
    15901 aggcagctcc ttcgcgccgt tctttgcggt ggaaaatgtc gccacaacca atggcaccta
    15961 tgtcctctct cgtctctctg gcgcagccat gttgaccgta acgatggtaa gaaaagcgga
    16021 ttacagcgga tatcgtttgt acatcacccc agagatggaa ggctacccga cagatgaaaa
    16081 tcaagccgct gcctatatga acaagattat cgagaaagag atcatgcgcg caccggagca
    16141 gtacctctgg atacaccgtc gctttaaaac gcgcccggtg ggtgaatcgt cgttatacat
    16201 ttaacaaacg gctctcactc tttccctcct caaatcagcc ataataacct catggttttt
    16261 atggcttttt ttcttaaggt tttttccttc gctgaatatc taattattac cgtcagaaat
    16321 taaactgtcg ccgatatgag acacctgtaa gttactaaaa gtaaataaga aaatgcctct
    16381 tgtctcgttt cagttttagg cgtacattag cgccgtctcg agcagtttag ctcagaattc
    16441 tgggatgatg cccacggtaa aatacaggac gtttaaggtc gttttgcccg gtgtcaactc
    16501 actgtatcag gtgtaatgaa gtcattcagg cgtaacagta attacgcgga gagatgtaaa
    16561 gtgaaatatt tctttatggg catttctttt atggtcatcg tttgggccgg tacttttgcc
    16621 ctgatgatct aaaagcaaac tgtgcaatga aaaacaggag ccattaggct cctgtttgca
    16681 tttctggcga aggcgtttat tccgcgtttt cgtgaatatg tttgctgctg gcgggtagta
    16741 aaccgtcggc acggaacatc gctttaatcc cacgaatcgc ctgacgaata cggtcgcggt
    16801 tttcaatcag tgcaaagcgc acatgcgtgt cgccgtagtc gccaaagcca atccctggag
    16861 agacacagac cttcgcttcg ttaagcaatt tcttggcaaa ttccagcgag cccatggcag
    16921 catacggttc cgggattttc gcccagacat acatcgaagc cttaggcatt tcgaccatcc
    16981 agcccgcttc atgcagccct ttcaccagca catcgcggcg gcgtttgtac tgttcggcaa
    17041 tatcgcgcac gcactgttga tcgccctcca gcgccgcaat agccgccacc tgcaacggcg
    17101 taaaggtgcc gtaatcgtga tagcttttaa tacgtgccaa cgcgctgacc agcgttttgt
    17161 taccgaccat aaagccgata cgccagcccg ccatgttgta gcttttcgac agcgtaaaga
    17221 actcgaccgc cacgtcgcgt gcgcccggca cctgcatgat tgacggcgct ttccagccat
    17281 cgtagacgat atcggcatag gccaggtcgt ggaccaccag cacatcgtag cgtttagcca
    17341 gcgccacaac cttctcaaag aattccagtt ccacgcattg cgcggttggg tttgacggga
    17401 agccgaggat catcatcttc ggtttcggat aactttcacg aatggcgcgc tccagttcat
    17461 tgaagaagtc gacaccttcc accagcggca ctgagcgtac ctgcgccccg gcaatcaccg
    17521 cgccgtaaat atgaatgggg tagcttggat tcggcaccag cactgtgtca ccatgatcca
    17581 gcgtcgccag catcaggtgc gccagcccct ctttcgaacc aatagtgacg atggcttctg
    17641 attccgggtc gatttcaacg tcgtagcgat cctgatacca gcgggaaatg gcgcgacgta
    17701 accgcggaat gccgcgtgaa gtggagtaac catgcgtgtc cgggcgctgg gccaccgtac
    17761 ataatttttc gacgatatgc ggcggagtcg caccgtccgg gttacccata ctgaaatcga
    17821 taatatcttc gccgcgccga cgcgcagcca ttttcagttc agcggtaatg ttaaaaacgt
    17881 agggcgggag acgatcaatg cgcgtaaagc gacgttcagg gcgagtgtca gccataattt
    17941 cctcagatta acgttagcgc ccggaccgtc cgagcgacgc tgccacgatg gtggctgttt
    18001 tgaaaatagc ctgattaatt tctgtctgtc cagcgtttta gaacattttt atcaatggct
    18061 ttaaatgagg aactccactt caaaaacagg aaatttatct acgctaacaa gaaaattacc
    18121 actcatttta tt
//
LOCUS       DAFGPF010000098        17966 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFGPF010000098 DAFGPF010000000
VERSION     DAFGPF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17966
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.098"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..5298
                     /locus_tag="LSX49_003765"
     CDS             <1..5298
                     /locus_tag="LSX49_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011478180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntS/YbdA MFS transporter"
                     /protein_id="HBL7170123.1"
                     /translation="INGDDATANNNGKTIVDGKDSTGTEIAGNNAVVNQDGTLDVSGG
                     GHGIDITGDSATVDNKGGMTVTDPDSIGILIDGDKAIVNNDGDNAISNGGTGTQINGD
                     DATANNSGKTIVDGKDSTGTEIAGNNAVVNQDGTLDVSGGGHGIDITGDSAKVDNKGG
                     MTVTDPDSIGIQIDGDKAIVNNDGDNAISNGGTGTQINGDEATVNNNGNTTVDGKDAT
                     GTEIAGNNAVVNQDGTLDVSGGAHGIDITGDGAIANTTGAITVADTDSVGIQVDGNAV
                     TVSNDGDSTITNGGTGTQVNGNDAQVNNTGNTTVDGKNSTGTEITGNNGTVNLDGGLI
                     VTGGAYGVEIAGDSAALNNEGDISVSDEGSIGVLINGEKATVSNTGDVNVSNNATGFD
                     ITTNEGNISLAGSMQVGDFSTGMDLNGNNNSVTLAAKDLNVTGQKATGVNVSGDANTI
                     NITGNVLVDKDQTADNAADYFYDPSVGINVNGSDNNVTLDGKLTVVADSELTTRGSAG
                     AIIFDGSQENITGLSIAGDGNTFRLNGGIQLVGEANKLTDGSTIASERKGSGKVPLVS
                     VDGKSSVHLNGDSTISGDVLLGNTQIIDLRNGAMLDVGADATINMQVDTYERYAMSAD
                     HLIDASSGSQLVNNGDINLRSIGFAAITGEDSFGSNTGNLTLSQYLDGLFANGGYGYL
                     ATKGASVVNTGTITTKVAEQESVINLGASLGFNDLVFYNAANSMTGLSAKTHGYVLNE
                     NGGKIEMFGRGNVGMLAIDESTAENAGQITLDALWVDVNDTTTLRDNIGNDARGYSVG
                     MGVGTDAGSGPRKNATAVNQQSGVITVYNAGIGMAAYGAGNTVINQGTINLEKNGNYD
                     SSLGVNSLIGMAAYNSGTAINDQTGVININADNGQAFYSTGNGVILNYGTICVNTNCL
                     TGNDYNDTDSYTSILYTGGDVITAQSETQSLTKKATISDKKDGNVVNSGALSGADIAI
                     SSGKLVNTSTGTINNAIIINGGALSNEGSVAKVTQNAGTFNNTGSVNSRMTQTGGTFN
                     NQQGGTVKNGSRLANSAIANNMGIWSLGDTSSGSNASMLEINNNAVFKNSGDFILDNS
                     KNAVHLNQSGTFYNTGKMLLSNSSHSGVLNFWGGNGRFINGGIADVTAKSLAVSASDA
                     GSSNAFFWNQSNGVVNFDKDSGVAVKFIHSNYVAQNDGTMNISGNNAIAMEGDKNARL
                     VNNGTINLGTSGTTDTGMIGMQLDSGTTADAVIENNGAINIYANNSFAFSMLGSVGHL
                     VNNGTVTIADGVTGSGLIKQGDSVNIEGVNGNNGNNSEVHYADYTLPDVPGSSVSVAA
                     STPSSDGSQNKLNGYVVGTSSDGSAGKLKVNNASLKGVSVNTGFTAGTSSTSVTFDNV
                     VQGSNLTDAETITSTSVVWNAQGTTDASGNVDVTMTKNAYTDVATDSSVNTVAQVLDA
                     GYTNNELYSSLNVGTTAELNSALKQVSGSQATTVFNEARVLSNRFSMLSDAAPEVANG
                     LAFNVVAKGDPRAELGNDTQYDMMALRKSLTLTEHQNLSLEYGIARLEGNGSDTAGDN
                     GVTGGYSQFFGLKHQMAFDNGMNWNNALRYDVHQLDSSRSVAYGDINKTADANVKQQY
                     LEFRSEGAKTFELREGLNVTPYAGVKLRHTLEGGYQERNAGDFNLSMNSGSETAVDSI
                     VGLKLDYAGKDGWSANATLEGGPNLSYVKSQRTASVSGAGSQRFNIDDGQNGGGFNSL
                     ATMGVKYSSQESALQVDAFHWKEDGISDKGVMLNFKKTF"
     gene            5518..6384
                     /gene="pdxI"
                     /locus_tag="LSX49_003766"
     CDS             5518..6384
                     /gene="pdxI"
                     /locus_tag="LSX49_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HBL7170124.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHLG
                     LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALARDGIAYVPFFPLGGFTPL
                     QSSTLSDVATSLNATPMQVALAWLLQRSPNILLIPGTSSVGHLRENMASDELVLTDDV
                     LATLDSIAQKAG"
     gene            complement(6424..7029)
                     /gene="azoR"
                     /locus_tag="LSX49_003767"
     CDS             complement(6424..7029)
                     /gene="azoR"
                     /locus_tag="LSX49_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBL7170125.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELITELKAHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTEKGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA"
     gene            7230..11132
                     /gene="hrpA"
                     /locus_tag="LSX49_003768"
     CDS             7230..11132
                     /gene="hrpA"
                     /locus_tag="LSX49_003768"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HBL7170126.1"
                     /translation="MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDHAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQQSAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQAADEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPADYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKTRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELIIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVTPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVK
                     EVRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            11405..12205
                     /locus_tag="LSX49_003769"
     CDS             11405..12205
                     /locus_tag="LSX49_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL7170127.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLNQAVERVHTAIVVQDPTMQRRTM
                     ATFRRITGDNPDAPRWLSYPGFVPQLGNNAESVIFVNPLQGLWPVERYLSLLTGELPR
                     LRDDSDGYGPRGRDFIVHVDFPAEVIQAWQTLKHDAVLIEAMESRSLR"
     gene            12415..13854
                     /gene="aldA"
                     /locus_tag="LSX49_003770"
     CDS             12415..13854
                     /gene="aldA"
                     /locus_tag="LSX49_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBL7170128.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAE
                     VEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGENVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADIELAVKAIVDS
                     RVINSGQVCNCAERVYVQKSIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVALGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEEAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(13896..14897)
                     /gene="gap"
                     /locus_tag="LSX49_003771"
     CDS             complement(13896..14897)
                     /gene="gap"
                     /locus_tag="LSX49_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL7170129.1"
                     /translation="MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYL
                     LKHDSNYGPFPWSVDYTEDSLIVDGKSIAVYAEKEAKNIPWKAKGAEIIVECTGFYTS
                     AEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAK
                     ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLV
                     IPELSGKLKGHAQRVPVKTGSVTELVSILGKKVTAEEVNNALKKATNNNESFGYTDEE
                     IVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL"
     gene            15086..15616
                     /gene="cybB"
                     /locus_tag="LSX49_003772"
     CDS             15086..15616
                     /gene="cybB"
                     /locus_tag="LSX49_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HBL7170130.1"
                     /translation="MGNKYSRLQISIHWLVFLLVIVAYCAMEFRGFFPRSDRPLINMI
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            15861..16034
                     /locus_tag="LSX49_003773"
     CDS             15861..16034
                     /locus_tag="LSX49_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170131.1"
                     /translation="MKKLALILVMGTLVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            complement(16106..16255)
                     /gene="hokB"
                     /locus_tag="LSX49_003774"
     CDS             complement(16106..16255)
                     /gene="hokB"
                     /locus_tag="LSX49_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HBL7170132.1"
                     /translation="MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            16518..16961
                     /gene="trg"
                     /locus_tag="LSX49_003775"
                     /pseudo
     CDS             16518..16961
                     /gene="trg"
                     /locus_tag="LSX49_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
     gene            complement(16999..17922)
                     /locus_tag="LSX49_003776"
     CDS             complement(16999..17922)
                     /locus_tag="LSX49_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7170133.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGQSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMNGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
BASE COUNT         4630 a         4257 c         4834 g         4245 t
ORIGIN      
        1 attaacggtg acgatgcgac cgcgaacaac aacggcaaaa ccattgtcga cggcaaagat
       61 tccaccggca cggaaatcgc gggtaataac gctgtagtga atcaggacgg tacgctggac
      121 gtcagcggcg gcggtcacgg tattgatatc accggcgaca gcgccacggt ggacaacaag
      181 ggcggtatga cggttaccga tccggattcc atcggtattc tgatcgacgg tgataaagcc
      241 atcgtcaaca acgacggcga caacgccatc agcaacggcg gtaccggcac acaaatcaac
      301 ggtgacgacg cgaccgcgaa caacagcggc aaaaccattg tcgacggcaa agattccacc
      361 ggtaccgaaa tcgcgggcaa caatgcggtg gtgaatcagg acggcacgct ggatgtcagc
      421 ggcggcggtc acggtattga tatcaccggc gacagcgcca aagtggataa caaaggcggt
      481 atgacggtta ccgatccgga ttccatcggt atccagatcg acggtgataa agccatcgtc
      541 aacaacgatg gcgacaatgc tatcagcaac ggcggcaccg gcacgcaaat taacggcgat
      601 gaagccaccg tgaataataa cggtaacacc actgttgatg gcaaagacgc caccggcacg
      661 gaaatcgcgg gtaacaacgc ggtggtgaat caggacggca cgctggatgt cagcggcggt
      721 gctcacggga ttgatatcac tggagacggc gccattgcaa acacgacagg agcgatcact
      781 gtagcggata cggactctgt cggtattcag gttgatggta atgcagtgac cgtcagcaat
      841 gacggagaca gcaccattac taacggcggt acgggcacgc aggttaacgg caacgatgct
      901 caggtcaaca atactggcaa caccacggta gacggcaaaa actccaccgg aacagaaatt
      961 acgggcaata acggcactgt aaatctggat ggtggtctga ttgtgacggg tggtgcctat
     1021 ggcgtggaga tcgctggcga cagcgccgcg ctaaacaatg aaggagatat ttcggtttcc
     1081 gatgagggct caattggcgt actcatcaac ggtgaaaaag caaccgtatc caacacgggt
     1141 gatgttaacg tcagcaataa cgcgacaggt tttgacatta ccactaatga agggaatatt
     1201 tcgctggcag gcagtatgca ggtgggcgac ttctctaccg ggatggatct aaacggtaat
     1261 aacaacagcg tcacgctggc ggcaaaagat ctgaacgtca ccggtcagaa ggcgacaggc
     1321 gtgaatgtat ccggcgatgc caacactatt aatatcaccg gtaatgttct ggtagataaa
     1381 gatcaaacgg ctgataacgc ggcagattat ttctacgacc cgtctgtggg gattaatgtc
     1441 aacggtagtg ataacaatgt cactctggac ggtaagttaa cggttgttgc tgacagtgaa
     1501 cttactacac gcggttctgc tggcgccatt atatttgatg gcagccagga gaatatcacc
     1561 ggactcagca ttgcaggtga tggtaatact ttccgtctga atggcggtat tcaactggtt
     1621 ggtgaggcga acaagctaac tgacggttcc actattgcat ccgagcggaa aggcagtgga
     1681 aaggtacctc ttgtcagtgt tgatggaaaa tcgtccgttc atctgaacgg ggattccact
     1741 attagcggtg atgtgctgct cggcaataca caaatcattg atttgcggaa tggtgccatg
     1801 ctggacgtcg gtgcggatgc cacgatcaac atgcaggttg atacttacga gcgttatgct
     1861 atgtcagccg atcacctcat tgatgcatcg tctggctctc agttggtcaa taacggtgat
     1921 attaatctcc gaagcatcgg ttttgccgct attactggtg aggattcatt cggaagcaac
     1981 actggcaatc tcacgctttc tcagtacctc gatgggctgt ttgcaaacgg agggtatggc
     2041 tatttagcca ccaaaggggc cagtgtcgtg aacacaggca ctatcactac gaaagtggcg
     2101 gaacaagaga gcgtaatcaa ccttggagcg tcactgggtt ttaatgattt agtcttttat
     2161 aacgcagcga acagtatgac gggccttagc gccaaaactc atggttatgt acttaatgag
     2221 aacggcggca aaatcgagat gttcggacgt ggcaatgtcg gtatgttggc catcgatgaa
     2281 agtacggcag aaaacgcggg gcagattaca ctggatgcac tgtgggttga tgtaaacgat
     2341 acaacaactt tgcgtgacaa cattggtaac gacgccagag gatattctgt tggtatgggc
     2401 gttgggacag atgctggcag tggaccgagg aagaacgcca cagcagtcaa ccaacagagt
     2461 ggtgttatca ccgtttataa cgccggaatt ggtatggccg cctacggcgc tggtaatacg
     2521 gttattaacc agggcaccat taatctggag aaaaacggta attacgatag tagcctgggc
     2581 gtgaattcgc ttatcggtat ggctgcatat aacagtggta ccgccattaa cgatcaaacc
     2641 ggtgttatca atattaatgc tgacaatggg caggcatttt atagcactgg taacggtgtc
     2701 attcttaact atggcaccat ttgtgttaac actaattgcc tgacgggcaa tgactataat
     2761 gatactgact cctatacctc gatattatac acgggtggcg atgtcatcac tgcacagagt
     2821 gaaacacaaa gtctgaccaa aaaagccacg attagcgaca aaaaagacgg taatgttgtt
     2881 aacagtggtg cgctttccgg tgctgatatt gcgattagta gcggtaagtt agttaataca
     2941 tcaacgggta cgattaataa cgcaataatt atcaacggcg gtgcgttaag taacgaaggc
     3001 tctgtggcga aggtgacgca aaacgccggt actttcaata acacagggtc ggttaacagt
     3061 cgtatgactc agacaggagg aacgttcaat aaccaacagg gcgggacggt gaagaacggc
     3121 tccagactgg ccaacagcgc tattgctaat aacatgggga tctggtccct tggcgatacg
     3181 agtagtggta gtaatgccag catgctggaa attaataata atgccgtgtt caaaaacagt
     3241 ggtgacttca ttctggataa tagcaaaaac gctgttcatc tgaatcagtc aggtacgttc
     3301 tacaataccg ggaaaatgtt gctatccaac tcttcccata gcggcgtact aaatttctgg
     3361 ggtgggaatg ggcgctttat taacggcggt attgcggatg tcacggcgaa atctttggcc
     3421 gtaagcgcca gtgatgccgg gagcagcaat gccttcttct ggaaccagag caatggggtc
     3481 gtcaattttg ataaagacag cggcgttgca gtgaaattca ttcacagcaa ttacgttgcg
     3541 cagaatgacg gcaccatgaa tattagcggt aataacgcta ttgcgatgga aggggataaa
     3601 aacgcacgac tggttaacaa cggcacgatc aacctcggaa cgtcgggcac gaccgacacg
     3661 ggcatgatcg ggatgcaact ggacagcggc acgacagctg atgcggtcat tgagaacaat
     3721 ggcgccatca acatttacgc caacaactcc tttgcattta gcatgttggg ttccgtaggc
     3781 cacctcgtga acaacggcac agtgactatt gccgatggag tgacaggttc cgggctaatc
     3841 aagcaaggtg acagcgttaa cattgaaggt gtgaacggca ataacggtaa caatagcgaa
     3901 gtgcattatg ctgattacac tttgcctgat gtacctggct cgtcggtttc tgttgcggcc
     3961 agcaccccgt ccagtgacgg aagccagaac aaactgaatg gttatgttgt aggaaccagt
     4021 tctgacggca gtgccggcaa gctgaaagtg aacaatgcaa gcctgaaagg ggtttctgtt
     4081 aacaccggat ttacggctgg aaccagctcc acctccgtga ccttcgacaa cgtcgttcag
     4141 ggcagtaatc tgaccgacgc agagacgatt acatcgacct ctgtggtatg gaacgcgcaa
     4201 ggcactactg acgccagcgg caacgttgat gtcacgatga ctaaaaatgc ctacaccgat
     4261 gtagcaacag attcatctgt taacaccgtc gcgcaggtac tggatgcggg ctataccaac
     4321 aacgagttgt acagcagcct gaacgtaggc accacggcgg aactgaacag tgcgctgaaa
     4381 caggtcagcg gcagccaggc aacaacggta ttcaatgaag cacgagtgtt aagtaaccgc
     4441 ttcagcatgt tgtccgatgc agcaccggaa gtcgcaaacg gtctggcctt caacgtggta
     4501 gcgaaaggcg acccgcgtgc tgaactgggt aacgacacac agtacgacat gatggcgctg
     4561 cgtaaatctc tgacgctgac tgaacatcag aacctgagtc tggaatacgg gattgcgcgt
     4621 ctggagggta atggttcaga taccgcaggc gataacggag tgacaggcgg ttacagccag
     4681 ttcttcggtc tgaaacacca gatggccttt gacaacggta tgaactggaa taacgccctg
     4741 cgttatgatg tgcaccagct cgacagcagc cgctcggtag cgtacggcga tatcaataaa
     4801 acagccgatg ctaatgtgaa acaacagtac ctggagttcc gtagtgaagg ggcgaaaacc
     4861 tttgagctgc gtgaagggct gaacgtcacg ccatatgccg gggttaaact gcgtcacaca
     4921 ctggagggtg gctatcagga acgcaatgcg ggtgacttta acctgagcat gaacagcggt
     4981 agcgaaacgg cagtggacag cattgttggg ctgaaactgg actatgccgg taaggacggc
     5041 tggagtgcga acgccacgct ggaaggcggc ccgaacctga gctatgtgaa aagccagcga
     5101 actgcgagcg tttcgggcgc gggaagccag cgtttcaaca ttgatgatgg tcagaatggt
     5161 ggtggtttca acagcctggc gacaatgggt gtgaaataca gcagccagga aagtgcgttg
     5221 caggtagatg cattccactg gaaagaagac ggcatcagtg ataaaggtgt gatgctaaac
     5281 ttcaagaaaa cgttctaatt tttagcatgt aatgcataaa ccgcaacgct gatacaggtt
     5341 gcggtttttt tattgccgga tgcggtgctt gacgtgtctt aacctgcctg gggtttcgtg
     5401 tctttcaggg caacagtaca actcatcccg caatcttgtt tacaccctcg cattatttat
     5461 ctcttttcgt ttctatactg atttttctta atccgtttta ttacagggca gggtgcgatg
     5521 agcagcaaca catttactct cggtacaaaa tccgttaacc gtcttggtta tggcgcgatg
     5581 caactggctg gtcctggggt ttttggcccc ccaagagatc gccacgtcgc tataaccgtg
     5641 ctgcgcgagg cgctggcatt gggcgtcaat catattgata ccagcgactt ttatggtccg
     5701 cacgtcacca atcagattat ccgcgaagcg ctttatcctt actctgacga cctgacaatt
     5761 gtcactaaaa ttggtgcgcg gcgtggagag gacgcatcct ggttacccgc attttctccg
     5821 gcagagctgc aaaaagcggt acacgataat ctacgtaatc tcggcctgga cgtactggat
     5881 gtggttaacc tgcgcgttat gatgggggat ggtcatggcc cagcggaagg atcgattgag
     5941 gccagcctga cagtgctggc ggagatgcaa caacaaggtc tggtaaaaca tcttggcctg
     6001 agtaacgtca caccgacgca ggttgcagag gcgcgaaaga ttgccgaaat cgtctgcgtg
     6061 cagaacgaat acaacattgc ccaccgtgct gatgacgcaa tgattgatgc tttggctcgt
     6121 gatggcattg cctacgtgcc gttcttcccg ctcgggggct ttacgccgct gcaatcctcc
     6181 acgctttccg atgttgctac aagccttaat gcgacaccaa tgcaggtggc gctggcgtgg
     6241 ctgttacagc gttcaccgaa tattttgctg attcctggca cctcttcggt ggggcatctg
     6301 cgggagaata tggcgtccga tgaattagtg ctaacggatg acgtgctggc aacgctggac
     6361 agtattgcgc aaaaggcggg ttaaataaaa aacctcccac tttcgtggga ggcatcataa
     6421 atcttatgca gcaacaatac tgtcgatggc tgcttttgcg tcagactgtg ctttcgctgc
     6481 catttccggg ccgtacgcga tcccttcggc gaagacaaat ttcacatcgg taatgccgat
     6541 aaagcccagg aatgtggaca gatatggcgt taccagatcc gttgggccat ctttatggat
     6601 cccaccgcgg ctggtgataa cgatggcttt tttaccggtg accaggcctt ccggaccctt
     6661 ctcggtatag cggaaagtaa cgcctgcacg tgcaaccagg tcaaaatagt ttttcaactg
     6721 ggtcgagata ttgaagttat acatcggtgc cgcaataacg ataacgtcgt gggctttcag
     6781 ctcggtaatc agctcatcgg aaagcgccag agcttcctgc tgacgcggag tcagcggcgc
     6841 atcgctcgga cgcagtgcac caaccagttc accatccagg accggaatcg gatttgcagc
     6901 caggtcacgc acggtgattt catcagcgga gtgcttttcg cgccattgtt caacaaaata
     6961 atcggacaac tgattagact gagagtaccc tgccaggatg ctggatttaa gaactaatac
     7021 cttgctcatg gtgtttcctt atagatattt gaatgggcaa tgccccgttg cttgttgaca
     7081 ctttattcac aatcctgcca cagagatagc gcaataaatc gaagcctatg ttcgaattta
     7141 ttgaacaacg catagaaagc tgcgatgtgg tactctatat ctatcattta aaagaaaatt
     7201 aatcaggcag cctactgccc actaacgtta tgacagaaca acaaaaattg acctttactg
     7261 ccttgcagca gcggctggat tcgttgatgc tgcgtgacag attgcgtttt tctcgccgtc
     7321 tgcacggtgt gaagaaggtt aaaaatcctg atgcacaaca ggccattttc caggagatgg
     7381 cgaaagagat tgaccatgcg gcagggaaag tcctgctgcg tgaagcggca cgaccggaga
     7441 ttacttaccc ggacaatttg ccggttagtc agaaaaagca ggacattctc gaagcgattc
     7501 gtgaccacca ggtggtgatc gtcgccgggg aaacgggttc cggtaaaacg actcagctac
     7561 cgaaaatctg tatggagctg gggcgcggga ttaaagggct gatcggccat acccagccgc
     7621 gtcggctggc ggcgcgaacg gtggcgaacc gtattgcgga agagctaaaa acggagccgg
     7681 gcggttgcat cggttacaaa gtgcgtttca gcgatcacgt cagtgataac acgatggtca
     7741 agctgatgac cgacggtatc ctgctggcgg agatccagca agaccgcctg ctgatgcagt
     7801 acgacaccat cattattgac gaagcgcacg aacgcagcct gaatatcgat tttctgctcg
     7861 gctatttgaa agagttgctg ccgcggcgtc ctgacctaaa aatcattatc acttccgcga
     7921 ctatcgaccc ggaacgcttt tcgcgccact ttaataatgc gccgattatc gaagtctccg
     7981 gtcggaccta tccggtggaa gtgcgctatc gcccgattgt tgaagaagcc gatgataccg
     8041 agcgcgatca gttgcaggcg atttttgacg ccgtagacga actgagccag gaaagccctg
     8101 gcgacattct gatctttatg agcggcgagc gagaaattcg cgataccgcc gatgcgctga
     8161 acaagctgaa cttacgccat accgaaatct tgccgcttta tgcacggctt tccaacagcg
     8221 aacagaaccg cgtgttccag tcgcacagcg ggcgacgcat tgtactggcg accaacgtcg
     8281 cggaaacctc gctgaccgta ccgggtatta aatacgttat cgacccaggt acagcgcgta
     8341 tcagccgcta cagctatcgc accaaagtgc agcgtttgcc gattgagcca atttcgcagg
     8401 cttcagctaa tcagcgtaaa ggccgctgtg gtcgtgtgtc cgaagggatc tgtattcgtc
     8461 tctattccga agacgatttc ctttcgcgcc cggagtttac cgatccggag attctgcgta
     8521 ccaacctggc ctcggttatt ttgcagatga ccgcactggg cttgggcgat atcgccgcat
     8581 tcccgtttgt cgaagcaccg gataaacgca atatccagga tggcgtgcgt ctgctcgaag
     8641 aactgggcgc gatcaccact gatgaacagc aaagtgctta taaactgacg ccgctcggtc
     8701 gtcagctctc gcagttgcct gtcgacccac gtctggcgcg tatggtgctg gaagcgcaaa
     8761 aacatggctg cgtgcgtgag gcgatgatta tcacgtccgc gctctccatt caggatccgc
     8821 gcgagcgtcc gatggataaa cagcaggcag ctgacgaaaa acatcgtcgc ttccacgaca
     8881 aagagtctga cttcctggca tttgtgaatc tgtggaatta tcttggcgag cagcaaaagg
     8941 cgctttcttc aaacgccttc cgtcgcctgt gtcgtaccga ttatctcaac tatctgcgcg
     9001 tgcgcgaatg gcaggatatc tacacccagt tgcgccaggt ggtgaaagaa cttggcattc
     9061 cggttaacag cgaaccggcg gattatcgcg aaattcacat tgcgttgctg accggtttgc
     9121 tttcgcatat cggcatgaaa gatgccgata aacaagaata taccggcgca cgtaacgcgc
     9181 gtttctccat cttccccggt tctggtttat tcaaaaagcc gccgaaatgg gtaatggtgg
     9241 cggaactggt agaaaccagc cgcctgtggg ggcgcattgc tgcgcggatc gacccggaat
     9301 gggtggagcc agttgctcag catttgatta aacgcaccta cagcgaaccg cactgggaac
     9361 gggcgcaggg cgcggtgatg gcaacggaaa aagtcactgt ttatggtttg ccgattgttg
     9421 ccgcgcgcaa ggtcaactac agccagatcg atccggcgtt atgtcgtgaa ctctttattc
     9481 gccacgcgct ggtggaaggt gactggcaga cgcgtcacgc attcttccgc gaaaacctga
     9541 aactacgggc ggaagtagaa gagctggaac acaaaactcg tcgccgcgat attctggtgg
     9601 atgacgaaac gttgtttgag ttctacgacc agcgcatcag tcacgatgtg atctctgcac
     9661 gccatttcga cagttggtgg aaaaaagtca gccgcgaaac gcctgatttg ctcaactttg
     9721 aaaagagcat gttgatcaaa gaaggggcgg aaaaaatcag caagctggat tacccgaact
     9781 tctggcatca gggcaatctc aagctgcgtt tgagttatca gtttgagccg ggggcagatg
     9841 ctgacggcgt gaccgtacat attccgctgc cgctgcttaa ccaggttgag gagagcgggt
     9901 ttgagtggca gatccccggc ctgcgccgtg agctgatcat cgccctgatt aaatcgttgc
     9961 cgaagccggt acgccgtaat tttgtacctg cgccaaacta tgccgaagcg tttttaggcc
    10021 gcgtcacacc gctggaattg ccgttgctcg acagccttga acgagagctt cggcggatga
    10081 ctggcgtcac cgttgaccgc gaagactggc actgggatca ggtgcccgat cacctgaaaa
    10141 tcaccttccg cgtggtggat gacaaaaaca agaagctaaa agaagggcgc tcattacagg
    10201 atctgaaaga cgccctgaaa ggcaaagtgc aggaaacgct gtctgccgtg gcggatgacg
    10261 gtatcgagca gagcggttta catatctgga gttttggtca actgccggaa agctacgagc
    10321 agaagcgcgg caactacaaa gtgaaggctt ggccggcgct ggtggatgag cgtgacagcg
    10381 tagcgatcaa actgtttgat aacccgctgg aacagaagca ggcaatgtgg aacggtcttc
    10441 gccgtttact gctgctaaat attccatcgc cgatcaagta cttgcacgaa aagctgccaa
    10501 acaaagccaa gctggggctg tactttaacc cgtatggcaa agtgctggag ctgatcgatg
    10561 actgtatctc ctgcggtgtg gatcaactga tcgacgccaa tggtggcccg gtctggacgg
    10621 aagaaggctt tgctgcgctg catgaaaaag tccgtgctga actgaacgac acggtggtgg
    10681 atattgcgaa gcaggtcgag caaatcctca ctgcggtgtt caatatcaac aaacgtctga
    10741 aagggcgggt ggatatgacc atggcgctgg ggctttctga cattaaagcg cagatgggcg
    10801 ggctggtgta tcgcggtttt gtcactggta acggcttcaa acgactgggc gacacgctgc
    10861 gatatttgca ggcaattgaa aaacgactgg aaaaactggc ggtcgatcca catcgcgacc
    10921 gtgctcagat gctgaaagtc gaaaacgtcc agcaggcgtg gcagcaatgg atcaacaaac
    10981 taccgcctgc acgtcgtgag gatgaagacg tgaaagaggt ccgctggatg atagaagagc
    11041 tgcgcgttag ttacttcgct caacaacttg gcacgcctta tccgatttcg gataagcgta
    11101 ttttgcaggc gatggagcag attagcggtt aacactgcta tttgcctgat aaatctaaaa
    11161 cccggtaagc atttagcgcc gggtttttta ttaattctaa aaacgataag ggaaaaaatt
    11221 caggagttca gaaaaataca attctctgct gcaagatgaa taatgtttat ctacagcatt
    11281 tccttaaaag atatgtcagg cttgcggagt ggcagttcag gaaatacgac ttcctccttt
    11341 cagagtgctc cgcttctcac tattatctca cgcagtattc ttaagggaac gataaggagg
    11401 aaccatgaat attaccccgt ttccgacgct ttcgccggca accatagatg ccataaatgt
    11461 tatcggacag tggctggcgc aggatgattt ctccggtgag gtgccgtatc aggccgattg
    11521 cgtgatcctt gcaggcaatg cggttatgcc gactatcgat gcggcatgta agattgcccg
    11581 cgatcagcaa attcctttac tgattagtgg tggtatcggt cactcgacaa cttttttgta
    11641 tagcgccatc gcacagcatc cgcactacaa cactatccgc accactggca gagcagaagc
    11701 taccattctg gcggatatcg ctcatcagtt ctggcatatt ccgcatgaaa aaatctggat
    11761 tgaagaccag tcaacaaact gcggtgaaaa cgcacgcttt agcatcgcgt tattgaatca
    11821 ggctgtagaa cgagttcata cggctatcgt tgttcaggac cccaccatgc agcggcgcac
    11881 gatggcgacg ttccgccgta taaccgggga taatcccgat gcaccacgct ggttaagtta
    11941 tcccggattc gttcctcagt taggaaataa cgcagagagt gtaatctttg ttaatccgtt
    12001 gcaaggatta tggccggttg agcgttatct atcgctactc actggcgagc tgccgcgttt
    12061 acgcgatgat agcgatggct acggcccccg cgggcgagat tttatcgttc acgttgattt
    12121 tccggcagaa gtcattcagg catggcaaac gctgaaacat gatgcggtgc tcatcgaggc
    12181 gatggaaagt cgctcgttac gttaaaaatt gcccgtttgt gaaccacttg tttgcaaacg
    12241 ggcatgattt ctgactttta tttctgcctt ttatttctgc ctttaattcc ttttacactt
    12301 gtttttatga agcccttcac agaattgtcc tttcacgatg ccgtctctct gatgattgat
    12361 gttaattaac aataaattta ccaaaaacaa acatgcaaat cacaggagtc gcccatgtca
    12421 gtacccgttc aacatcctat gtatatcgat ggacagtttg ttacctggcg tggagacgca
    12481 tggattgatg tggttaaccc tgctacagag gctgtcattt cccgcattcc cgatggtcag
    12541 gccgaggatg cccgtaaggc aatcgatgca gcagaacgtg cacaaccaga atgggaagcg
    12601 ttgcctgcta ttgaacgcgc cagttggttg cgcaaaatct ccgccgggat ccgggaacgt
    12661 gccagtgaaa tcagtgcgct gattgtcgaa gaagggggca agatccagca gttggctgaa
    12721 gtcgaagtgg cttttactgc ggactatatc gattatatgg cggagtgggc acggcgttac
    12781 gagggcgaga ttattcaaag cgatcgtcca ggagaaaata tccttctgtt taaacgtgcg
    12841 cttggcgtga ctaccggcat tctgccgtgg aactttccgt tcttcctcat tgcccgcaaa
    12901 atggctcccg ctcttttgac cggtaatacc atcgtcatta aacccagtga atttacgcca
    12961 aacaatgcga ttgcattcgc caaaatcgtt gatgaaatag gccttccgcg cggcgtgttt
    13021 aaccttgtac tcgggcgtgg tgaaaacgtt gggcaagaac tggcgggtaa cccaaaggtt
    13081 gcaatggtca gtatgacagg cagcgtctct gcaggtgaaa agattatggc gactgcggcg
    13141 aaaaacatca ccaaagtgtg cctggaattg gggggtaaag caccggctat cgtaatggac
    13201 gatgccgata ttgaactggc agtcaaagcc atcgttgatt cacgcgtcat taatagtggg
    13261 caagtgtgta actgtgcaga acgtgtttat gtacagaaaa gcatttatga tcagttcgtc
    13321 aatcggctgg gtgaagcgat gcaggcggtt caatttggta accctgctga acgcaacgac
    13381 attgcgatgg gaccgttgat taacgccgcg gcgctggaaa gggttgagca aaaagtggcg
    13441 cgcgcagtag aagaaggggc gagagtggcg ttgggtggca aagcggtaga ggggaaagga
    13501 tattattatc cgccgacatt gctgctggat gttcgccagg aaatgtcgat tatgcatgag
    13561 gaaacctttg gtccggttct gccggtggtc gcatttgaca cgctggaaga ggctatctca
    13621 atggctaatg acagtgatta cggcctgacc tcatcaatct atacccaaaa tctgaacgtc
    13681 gcgatgaaag ccattaaagg gctgaagttt ggtgaaactt acatcaaccg tgaaaacttc
    13741 gaagctatgc aaggcttcca cgctggatgg cgtaaatccg gtattggcgg cgcagatggt
    13801 aaacatggct tgcatgaata tctgcagacc caggtggttt atttacagtc gtagtgagtg
    13861 aaagaggcgg aggttttttc ctccgcctgt gcgcgtcaga gtttagcgaa tttttcgagg
    13921 gtgcgaataa gctgcgtgac gaagccatat tcgttatcgt accaggcgac cgttttcacc
    13981 agttgtaaat cgcccacggc ggtaatttcc gtttgcgtgg catcaaacac cgaaccgaaa
    14041 tggctgccaa tgatatcgga agagactatt tcttcatcgg tataaccaaa tgactcgtta
    14101 ttgtttgtcg cctttttaag cgcgttgttc acctcttcgg cagtcacttt ttttccgaga
    14161 atcgacacca gttcagtgac cgaacctgtt ttcaccggca cgcgttgcgc atgacctttc
    14221 agtttgccgc tcagttccgg gatcaccagg ccaatggctt ttgccgcccc cgtagtgtgg
    14281 ggaatgatat tttctgccgc tgcgcgtgaa gcacgtaaat ctttaccacg cgggccatcc
    14341 accagtgact gggtgccggt ataggcatga atggtcgtca tcgtgccgac ttctatcccg
    14401 aaactgtcat gcaaggcttt ggccatcggc gcaaggcagt tagtggtgca tgacgccacg
    14461 gaaacaatgg tgtcgttgcc atccagagtg tcgtcattga cgttataaac gatggttttc
    14521 atttcaccgg caggggcgga aatcaacacc ttcttcgcgc cagcatcaag atgcgcctgc
    14581 gatttctcgg cggaggtata aaagcctgta cattcgacaa tgatttctgc gcctttcgct
    14641 ttccacggaa tatttttagc ctctttttcg gcgtaaaccg cgatactttt cccatcaacg
    14701 ataagtgaat cttccgtata atcaacgctc caggggaacg gtccgtagtt tgaatcatgt
    14761 ttcagcaggt aggcgagaat ttttggggaa gtgagatcat taatagcgac aacgtctatg
    14821 ttgcttttga cttcaagtaa tcgacgcaac accagtcgac cgatacgacc aaaaccatta
    14881 ataccaactt tactcatggt cttctcctgt caggaacgtt cggatgaaaa ttgatccttt
    14941 ccaggcttag accaggatgg cgggatgggc aatctacatt cttgcagtga aacgtaacgt
    15001 actgaaaacg ggtgaacaat atttaatgaa attttaagaa aagcccgtta tgttaacggc
    15061 aaattatgtt aaagcaggaa atgttatggg aaataaatac tcaaggttac aaatcagcat
    15121 tcactggctg gtctttttgc tggttatcgt agcgtattgc gcaatggagt ttcgtggttt
    15181 cttcccacgt agcgatcggc ccctcatcaa catgattcat gtttcctgtg gcatctcaat
    15241 tctcgtactg atggtggttc gtcttttgtt aaggctgaaa tacccaaccc cgccgattat
    15301 acctaagcca aaaccgatga tgacgggact ggcgcatttg ggccatttgg tgatttatct
    15361 cctgtttatt gcgctgccgg tgattggttt ggtgatgatg tataaccggg gcaacccgtg
    15421 gtttgcgttt ggtttgacga tgccttacgc ttcagaggcc aatttcgagc gggttgatag
    15481 cttaaagtcg tggcatgaaa cgctggcgaa tctgggatat tttgtcatcg ggttgcacgc
    15541 tgcggctgca ctggcacacc actatttctg gaaggacaac acacttctac gcatgatgcc
    15601 acgtaaacgt tcctgaagga tatttaaaga aaacgcctgt actaaaaccg acccgtggta
    15661 caggcgaaga atacgggcct acatcggaag cgcctattat atttatttgt atgacaaata
    15721 aaaccataat ccttgtctat acgtccatct ggcttatctt taatcaattc acccgatctt
    15781 tgatctcatc aacggtatca aaataaacca gcgtataacg ttcaaatcga acataagatt
    15841 cgataaatca tggaggttat atgaaaaaac tggcacttat cctggttatg ggaacgcttg
    15901 tttcctttta tgccgatgcc gggcgcaaac cctgttctgg ttcgaaaggg gggatctcac
    15961 actgtacggc aggcggcaaa tttgtctgta atgatggttc tattagtgca tcgaaaaaaa
    16021 catgcactaa ctgaagtgta aaaggggggc catgagaaaa tgaatccgct agtcagatgc
    16081 gcggggaaaa cccccgcgct tgcccttacc tggacgtgca ggccatgagc gcagcaacct
    16141 ccttatcacc gtcccggaac cgcagttcgt agagcgtttg tcgggtcagg agtgtgaatg
    16201 tcagaatcgt aatgcagata atgagcagac acaccaccag agggttgtgc ttcatagcct
    16261 ttctccttgc cggatggcgg gtaagaggct aagatctgaa ttgctaggtt cattcgttgg
    16321 cctcggttga tagaaatatc ggtcggggcc ttcgtctttc tgattccagg ttagcctgaa
    16381 aacagaaagt ctcaggcacc cgtgagcatc ctatgtggtt tccttaggga cgaaaataat
    16441 cacctgacga aatcgcgtgc tgctttccag aatttttcgt cattcggttt agccagttta
    16501 atcattcgtt actctcgcaa ggccgtggat ttgccgttgt cgccagcgaa gtacggacac
    16561 tcgcaagccg cagcgcccag gcggcgaaag agattgaagg cttgatcagt gaatcagtca
    16621 ggttaattga cctgggatcg gatgaggtgg caacggcagg gaaaaccatg tgcactattg
    16681 ttgatgccgt cgcgagtgtc acacatatca tgcaggaaat cgccaccgcc tcgggtgaac
    16741 aaagtcgagg cataacgcag gttagccagg cgatttctga aatggataag gtgacgcaac
    16801 agaatgcttc tctggtagaa gaggcctcaa cggcggcggt gtcccttgaa gaacaggcgg
    16861 cacgactaac tgaggcggtg gacgtattcc gtctgaacaa acattctgtg tcggcagaac
    16921 cacgaggagc gggtgaacca gttagttttg ctacggtgtg aaaatgttaa aggagggatc
    16981 gacagatccc ttcacctttc agaacggcat tgattttcga atagcgttaa tcatcaactg
    17041 gcaaccagaa gagaacgtcg catctacgcg ggtcagtatt ccaatcggtt cgcctgcacc
    17101 atgtcccgga acaggcaggg ctaccagcgt ggcatgacgc aggtcgtctt ttacagcgcc
    17161 agaagggaca aaccacacgt aatcgtattc aaccgtaagt tgacgagata gcgaagcaga
    17221 cagcgtttcg atacaacccg aaggaatttt acatccctgg ctctgcacta atgcatctga
    17281 atgctggcgt ggcgcagtgc cttctggtga tacaacgacc ggccattcca gcacccggct
    17341 tagcgttacg ttctcctgaa gtagcgggtg attagggcgg acaaccagct tcagcgattc
    17401 aagaaacagt agttcgtaat taagcccgtt catcagttca ggatctgaca tccgaccaat
    17461 gccgatatcg atttccccgg tttttaaacc cgccagaatc atagggttac tcattgtcgc
    17521 aacttgcaag gtcgtctctt tttgttgctg atgaaactga cctataaccg aaggtaatat
    17581 ccctagtgcc gcagtaggta gcgcaccaac cctgacgaca tcattattaa gaccttcttt
    17641 acgatgaagc gactgtccgg cagtgttgat ggcgtcaaga actctgactg catgcgttaa
    17701 aaattgttcg ccgggtaagg taagttgcgc cccctgacga ccacgctcaa acaagcgagc
    17761 gcccgtcagc tgctccagtt cattcaatgt cttagagagc gcaggttgac tcaaattaag
    17821 ggtttcagcc gcgcgcccca aagttccttg ttgtgcgaca gctacgaatg tatgaaggtg
    17881 gcgcaaacgg atgcgctgac taaacagact atttttttcc ataagcgatg ttaaaaacga
    17941 agcggtgtcg ctgacaagtg aagttg
//
LOCUS       DAFGPF010000099        17871 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFGPF010000099 DAFGPF010000000
VERSION     DAFGPF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17871
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.099"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            16..1491
                     /locus_tag="LSX49_003777"
     CDS             16..1491
                     /locus_tag="LSX49_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBL7170134.1"
                     /translation="MIRSTRISLGLFFNYFLSLTKIDLGQNYISLPSIKSSTHIALLF
                     MASMGTQKLKAQGFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNA
                     VIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVIIHKPINGSTLIQTKSNDVS
                     IFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYN
                     ADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLA
                     SLCCNLLLLTLDEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLT
                     NIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQ
                     QSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTI
                     SIGTVFSTGDTHNISLVMTEADKALREAKSEGGNKVIIHHI"
     gene            1672..3162
                     /locus_tag="LSX49_003778"
     CDS             1672..3162
                     /locus_tag="LSX49_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBL7170135.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     RADSSFLYDKYQNQSIAAHVMRALAAEQSEVPPEQRRAICEAFESANNTHGLNLTAHK
                     YQGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            3205..3708
                     /gene="yeaK"
                     /locus_tag="LSX49_003779"
     CDS             3205..3708
                     /gene="yeaK"
                     /locus_tag="LSX49_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HBL7170136.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGANFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
                     VNFRRTA"
     gene            complement(3709..3813)
                     /locus_tag="LSX49_003780"
     CDS             complement(3709..3813)
                     /locus_tag="LSX49_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170137.1"
                     /translation="MNDQMFVETLIITSSFFAIAAVLVLSVLLIERTG"
     gene            3983..4429
                     /locus_tag="LSX49_003781"
     CDS             3983..4429
                     /locus_tag="LSX49_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBL7170138.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            complement(4386..5207)
                     /gene="nimR"
                     /locus_tag="LSX49_003782"
     CDS             complement(4386..5207)
                     /gene="nimR"
                     /locus_tag="LSX49_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NimR"
                     /protein_id="HBL7170139.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVKHSNQVTANAELCFLFIEPSAVTMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPGSSHPKI
                     RTMVEMMAKEPVEWGSLRQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIAGLTTVSPQSAKPDPRQ"
     gene            5304..6485
                     /gene="nimT"
                     /locus_tag="LSX49_003783"
     CDS             5304..6485
                     /gene="nimT"
                     /locus_tag="LSX49_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HBL7170140.1"
                     /translation="MTCSTSLSGKNRIFLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISQGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGDWSVPLMGVAILSLLMAIFGLCAGRDKEI
                     R"
     gene            6540..6887
                     /locus_tag="LSX49_003784"
     CDS             6540..6887
                     /locus_tag="LSX49_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBL7170141.1"
                     /translation="MNIQCKRVYDPAEQSDGYRVLVDRLWPRGIKKTDLALDEWNKEI
                     TPSTELRKAFHGEVVDFATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYSAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(6909..7163)
                     /gene="yoaF"
                     /locus_tag="LSX49_003785"
     CDS             complement(6909..7163)
                     /gene="yoaF"
                     /locus_tag="LSX49_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HBL7170142.1"
                     /translation="MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRDHPAGEK"
     gene            7346..8371
                     /gene="dgcP"
                     /locus_tag="LSX49_003786"
     CDS             7346..8371
                     /gene="dgcP"
                     /locus_tag="LSX49_003786"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HBL7170143.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMHIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENADISSLRERI
                     QQQIRGEYHLGDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     THSALHS"
     gene            8404..8502
                     /locus_tag="LSX49_003787"
     CDS             8404..8502
                     /locus_tag="LSX49_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HBL7170144.1"
                     /translation="MRIGIIFPVVIFITAVVFLAWFFIGGYAAPGA"
     gene            8505..8579
                     /gene="yoaJ"
                     /locus_tag="LSX49_003788"
     CDS             8505..8579
                     /gene="yoaJ"
                     /locus_tag="LSX49_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HBL7170145.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(8638..8886)
                     /locus_tag="LSX49_003789"
     CDS             complement(8638..8886)
                     /locus_tag="LSX49_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL7170146.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(9034..9216)
                     /locus_tag="LSX49_003790"
     CDS             complement(9034..9216)
                     /locus_tag="LSX49_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HBL7170147.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVN
                     TVRSYDTENEHDVCGW"
     gene            complement(9220..9579)
                     /gene="yeaR"
                     /locus_tag="LSX49_003791"
     CDS             complement(9220..9579)
                     /gene="yeaR"
                     /locus_tag="LSX49_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HBL7170148.1"
                     /translation="MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLS
                     VMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPEKWHNIEAMTDDTYFNIDFFVAP
                     EVLMEGAQQRKVIHNGK"
     gene            complement(9752..10390)
                     /gene="leuE"
                     /locus_tag="LSX49_003792"
     CDS             complement(9752..10390)
                     /gene="leuE"
                     /locus_tag="LSX49_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HBL7170149.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGK
                     NSETKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS"
     gene            complement(10517..10849)
                     /locus_tag="LSX49_003793"
     CDS             complement(10517..10849)
                     /locus_tag="LSX49_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7170150.1"
                     /translation="MSLTPNALDTTTSKYRFLNDDFILCSFIHSTAWRGIFAFGVFPD
                     HVKIDVARLFPASGHLVQVLPEYYQPANVWAVYVSKLSTSAKVRITVEFLRQYFAEHY
                     PNFSLEHA"
     gene            complement(10933..12048)
                     /gene="rnd"
                     /locus_tag="LSX49_003794"
     CDS             complement(10933..12048)
                     /gene="rnd"
                     /locus_tag="LSX49_003794"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310540.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HBL7170151.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQALPEEALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ"
     gene            complement(12130..13815)
                     /gene="fadD"
                     /locus_tag="LSX49_003795"
     CDS             complement(12130..13815)
                     /gene="fadD"
                     /locus_tag="LSX49_003795"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HBL7170152.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSL
                     TEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            complement(14020..14601)
                     /gene="yeaY"
                     /locus_tag="LSX49_003796"
     CDS             complement(14020..14601)
                     /gene="yeaY"
                     /locus_tag="LSX49_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HBL7170153.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVN
                     GFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPI
                     EPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            complement(14641..15336)
                     /gene="tsaB"
                     /locus_tag="LSX49_003797"
     CDS             complement(14641..15336)
                     /gene="tsaB"
                     /locus_tag="LSX49_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBL7170154.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPELVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLVLHDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            complement(15394..17304)
                     /locus_tag="LSX49_003798"
     CDS             complement(15394..17304)
                     /locus_tag="LSX49_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBL7170155.1"
                     /translation="MTDDFAQDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTIDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKTGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            17436..17780
                     /locus_tag="LSX49_003799"
     CDS             17436..17780
                     /locus_tag="LSX49_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBL7170156.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
BASE COUNT         4442 a         4508 c         4259 g         4662 t
ORIGIN      
        1 caatcattcg gaaaaatgat tcggtcaaca cgtatttccc tggggttatt ctttaattat
       61 tttttatcgt taacgaaaat tgatcttggt caaaactata tatctctgcc atcaataaaa
      121 tccagcactc acattgctct cctttttatg gcttctatgg gtacacaaaa attaaaagct
      181 caaggctttt ttattttcag cttattgctg acgttaattt tattttgcat tactacctta
      241 tataacgaaa acacgaatgt aaaactcatc ccacagatga attacctgat ggttgttgtg
      301 gctttgtttt tccttaacgc cgtcattttt cttttcatgt taatgaagta tttcactaac
      361 aaacaaattt taccaacact cattttaagc cttgcatttt taagtggcct tatctattta
      421 gttgaaacca ttgtaattat ccataaacca atcaacggca gtacactgat ccagacaaag
      481 tcgaatgatg tttctatttt ctatattttc cgccaactca gtttcatttg tttaacctcg
      541 ctggcgctct tttgttatgg gaaagacaac atccttgaca acaataagaa aaaaactggc
      601 attctgttgc tggcgctgat tcctttttta gtttttcccc ttctggcaca caatctgagc
      661 agttataacg ctgactattc tttgtatgtc gtcgattact gcccggacaa ccatactgcg
      721 acctggggaa tcaactatac aaaaatattg gtttgtttgt gggcattttt actgttcttt
      781 attatcatgc gtacacgatt agccagcgaa ctatggccgt taatagcatt attatgtctg
      841 gcatcgctat gctgcaactt acttctactg actctggatg agtataatta caccatctgg
      901 tatatcagtc gcgggattga agtttccagt aaactgtttg ttgtgtcttt tctgatttat
      961 aacatttttc aggaactgca actctccagc aaactggcag ttcatgatgt gctgaccaat
     1021 atttataatc ggcgctactt tttcaacagc gtagagtcat tattgtcgcg acctgttgtt
     1081 aaggactttt gtgtcatgct ggttgatatt aatcagttca aacgcatcaa tgcccaatgg
     1141 ggacatcgtg tgggtgataa agtgctggta tcaattgtcg atattatcca gcaaagcatc
     1201 cgccccgatg atattttagc gcgactggag ggtgaggtgt ttggcttgct atttaccgaa
     1261 ctcaatagtg cccaggcaaa aatcattgcg gaacgtatgc gtaaaaatgt cgaactcctg
     1321 accggcttta gtaacagata tgatgttcct gaacaaatga ccatcagtat tggcacggtt
     1381 ttttcaacgg gtgacacgca taatatctcg cttgtcatga cggaagcaga taaagcctta
     1441 cgcgaagcga aaagcgaggg gggcaacaaa gtgattattc atcatattta agtgcaaaaa
     1501 tattcacagc catgcttttt gcgtggcttt tgcatacaat ttattactat tacccctaaa
     1561 tttcccctcc ccagcggcgc agagatgagt ataattagcg cccctgtgcc aggccgcaat
     1621 cgaactttat ctggttttct cgtttcacta accgaaggag tgccatttat catgaaattg
     1681 caccatagaa tgctccggca ttttatcgcc gcaagtgtca ttgtgctgac atcttccttc
     1741 cttatttttg aacttgtcgc cagcgacaga gcaatgagtg cctatctgcg ctatatcgtg
     1801 cagagagcag actcttcctt tctttatgat aagtatcaga atcagagtat tgccgcgcat
     1861 gtgatgcgcg ctctcgctgc tgagcagtcg gaagtaccgc cagaacaacg gcgcgctatc
     1921 tgcgaggctt ttgagtctgc caataatacc catggcttaa acctgactgc tcataaatac
     1981 cagggcttac gcggcacact acaaaccgca tccactgact gcgacacaat tgtggaagct
     2041 gcagcactat tacccgcttt tgatcaggca gtggaaggca accgccacca ggatgattac
     2101 ggttcaggtc ttgggatggc cgaagagaaa tttcactatt atctcgatct caatgaccgc
     2161 tatgtctatt tttatgagcc ggttaatgtt gaatactttg cgatgaataa ctggtccttc
     2221 ctgcaatcag gaagtattgg tatcgatcgc aaagatattg aaaaagtatt taccgggcgt
     2281 accgtattat cgagcattta ccaggatcag cgtactaaac agaacgtgat gagtttgctg
     2341 acgccggtat atgtcgcagg gcagctaaaa gggattgtgc tgctggatat taacaaaaac
     2401 aatctgcgga atatctttta cactcatgac cgccctctcc tctggcgttt tctcaatgtc
     2461 acgctaaccg atacagattc ggggcgcgac attatcatca accagagcga agataatctg
     2521 ttccagtatg tcagttacgt ccatgactta ccgggcggca ttcgtgtctc gttatccatt
     2581 gatattcttt actttatcac gtcttcgtgg aaaagcgttc tgttctggat tttgacggcg
     2641 ttaattttgc tgaatatggt gcggatgcac ttccgcttat accaaaatgt gtcgcgagaa
     2701 aatattagtg atgcgatgac tggactctat aatcgcaaaa ttttaacccc tgaactggag
     2761 cagcggttgc agaaactggt gcaatccggt tcttcggtga tgtttattgc tattgacatg
     2821 gacaagttaa agcaaataaa tgacaccctc ggtcatcagg agggggattt agcgattacg
     2881 ttattagctc aggcgattaa acagtcgatt cgtaaaagtg attatgccat ccgactcggt
     2941 ggcgatgaat tctgcatcat tcttgtcgat tcgacgccgc aaattgcagc acaactgcct
     3001 gaacgtatcg aaaaacgtct gcaacatatc gcgccgcaga aagagatcgg cttctcttcc
     3061 ggtatttacg cgatgaaaga aaacgatacg ttacatgatg cgtataaagc ttccgatgag
     3121 cgtttatatg tcaataagca gaacaaaaac agccgttcat gataaccttc tgtggttgtt
     3181 tgcttgtaat ctcaggagca tgaaatgact gaaatggcta aaggaagcgt gacgcatcag
     3241 cggttaatcg ctttattatc acaagaaggt gctaacttcc gcgtcgttac ccatgaagcg
     3301 gtaggtaaat gtgaagcagt gtcagaaatt cgtggcaccg ctttaggcca gggggctaag
     3361 gcactggtat gtaaagtcaa aggcaatggc gtaaatcaac atgttctggc gatcctcgct
     3421 gccgatcaac aggccgatct gagccaactc gccagccata taggcggatt acgcgcttcg
     3481 ttggccagcc cggcggaagt cgatgaactc acaggctgtg tcttcggcgc gatcccccct
     3541 ttcagcttcc atccaaaact caaactggtt gccgaccccc tactcttcga acgatttgat
     3601 gaaatcgcct tcaatgcagg catgctggat aaatccgtta ttttgaaaac cgcggattat
     3661 ttgcgtattg cgcaaccaga actggtcaat ttccgccgca ctgcgtaact agcctgtccg
     3721 ttcaataagc agaacggaca aaaccagcac agcagcaatg gcaaaaaacg atgacgtgat
     3781 aatcagtgtc tcgacgaaca tttgatcgtt catagtatgc ccccgggaga tagctgtttt
     3841 cacgttattg ttaacgtaca caaatggcag tttgatgaca gttcgtctga ttttttatgc
     3901 aaaaaacgta aagattttct acttcctgcc tgcagcaagc gtaaagtaag caggcttatt
     3961 attttttggc aaggaaacca cgatgtttga tgtcactttg ctgatcctgc tcgggttagc
     4021 tgcgctgggc tttatcagtc ataacaccac tgtcgccgtt tcaattctgg tgttgattat
     4081 tgtccgcgtc acaccgttaa gcaccttttt cccgtggatt gaaaaacagg ggctaagtat
     4141 cgggataatc attctgacga ttggcgttat ggcccccatc gccagcggga cgctaccgcc
     4201 ctcaaccctg attcactcgt ttctgaactg gaaatcgctg gtggcaattg cagtcggcgt
     4261 tattgtctcc tggctggggg ggcgcggcgt gacgttaatg ggcagccagc cgcaactggt
     4321 cgccgggctg ctggtgggca ctgttttagg cgtggcgctg tttcgcggcg taccggttgg
     4381 cccgcttatt gccgcgggtc tggtttcgct gattgtgggg aaacagtagt taatcccgca
     4441 atatatcggc ctggcgtttg ccccaggcct ttcttaaaca tagtaataaa ggccgttgtt
     4501 gaatcatacc ccagtgtatg agcaactttc tgtacagtat cgcctttcac taatccctga
     4561 agcgccataa tcagctgtaa ctgctgacgc cactggcgaa aactcaaccc cgtctctttc
     4621 actatcagcc gggcaagatt gcgttcactc atcgcaaaaa agccagccca ttgcctcaat
     4681 gagccccact cgacgggctc tttcgccatc atctccacca tcgtgcggat tttaggatga
     4741 gaagaaccgg gcaagtgcag ctgttgttgt ggttgctgag ggagttcatc aaacaggacc
     4801 tgaattaatc tgcgggtcat cggctcagca cgctgagtcg tcgtcctgtt tgccagggtt
     4861 aaaattaatt cccggcataa gggcgatatt ttcaatgtgc aacatgttgt cggcattgtc
     4921 actgcgctgg gctcgataaa cagaaaacag agttcggcgt tagctgtcac ttgattacta
     4981 tgtttcaccc cgcccggtat ccaaaccgca tattgtggcg gcaccatcca caaagcattt
     5041 tctaccgtac aggtaattgc accatgtagt gccagtatca actgcccttt gcggtgctga
     5101 tgtacaggac tggttaactc atccgttccg gcgtgaatac aaaatgcgac cgcggcttca
     5161 tggtgtcggt cgggttcata gccattgaga ttcaacctgt gcatcatttt gtccgaattt
     5221 agcgatattt tgtcatttta gcttgattca acataacaat aaaaacggta aggtacagcc
     5281 tcgtttgtaa caatgagaag catatgacct gttcaacttc attaagcggt aaaaacagga
     5341 ttttccttat cgctggcatt ctgatgattg ccacaacatt acgcgtcacc tttaccggcg
     5401 cagcaccgtt actggatacg attcgttccg cttactcgct aacgacggcg caaaccggct
     5461 tattgaccac cctgccatta ttagcctttg cgctgatctc accgctggcc gccccggtgg
     5521 cgcgacgttt tggtatggaa cgtagcctgt ttgccgcgtt acttttgatc tgtgcaggta
     5581 tcgcaattcg ctctctccct tcgccttact tattatttgg cggtacagcg gtcattggcg
     5641 gtgggattgc attaggcaat gtcttactgc caggattaat taaacgcgat ttccctcatt
     5701 ccgtcgccag acttaccggc gcatattccc tgacaatggg agctgcggcg gcactgggat
     5761 cggcgatggt agtgccgctg gctttgaacg gttttggctg gcaaggcgcg ttgctcatgc
     5821 tgatgtgttt tcctctgctg gctctttttt tatggctgcc acagtggcga agtcaacaac
     5881 atgcaaattt gagtacctca cgcgccttac atactcgggg tatctggcgt tcgccgcttg
     5941 cctggcaggt aacattgttt cttgggatca actcactggt ctattacgtg attattggct
     6001 ggcttccggc gatcctcatc agtcaaggct atagcgaagc acaggcgggt tcactgcatg
     6061 gtttgctgca actagccaca gcagctcccg gtttgctgat cccacttttc ttacatcatg
     6121 tgaaagatca gcgtggtatt gcagcgttcg ttgccttgat gtgcgcagtg ggtgcggttg
     6181 ggctctgctt tatgccagca cacgcgatca cctggactct gcttttcggt tttggttccg
     6241 gcgcaacaat gatactgggg ttgacgttca ttggtcttcg ggcaagttct gcgcatcagg
     6301 cggcggcact ctcggggatg gcacaatccg tcgggtattt gctggcagcc tgtgggccgc
     6361 cgctgatggg taaaatacac gatgctaacg gtgactggtc cgtaccactg atgggtgttg
     6421 caatactttc actactgatg gcgattttcg gactttgcgc cgggagagac aaagaaattc
     6481 gctaatatcc ggtgctatag tgacgtgaca aatcatgcgt gaaagggaga acaaatacga
     6541 tgaatattca gtgcaaacgc gtttatgatc cggctgaaca gagcgatggt tatcgcgtac
     6601 tggtcgaccg cctctggcca cgcggtatca aaaaaaccga tttagccctt gatgagtgga
     6661 ataaagaaat cacgccgtca acggagctgc gcaaagcctt tcacggcgaa gtcgtcgatt
     6721 ttgcaacctt tcgcgagcaa tatcttgcag aactggcgca acacgagcaa gaaggaaagc
     6781 ggctggcaga catcgccaaa aaacagccgc tgaccctgct ctactcagca aaaaacacca
     6841 cgcagaacca tgcgctggtg ctggcagact ggctacgtag cttgtgattt tagtacagca
     6901 tccggcggtt atttttcacc agccggatgg tcccgtcgcc acaatgccca ttcatcaatc
     6961 gtttcaccgc ccggtaattt gcaattgttg ctgacccctt gcgctgtctg cacaggaatg
     7021 agcgtcccgc ccttctgctg gcaatagacc gacgccggat ttgccatacc aatctgcggc
     7081 ggtttaggtg cttctggctg agaaggggtt gaacaaccag ccaggaccag caagcaaggc
     7141 agaacaaaac tgataatttt catttattga tctcacatat ttatccaggc ttagagtatc
     7201 gcggtatcgt tttgttttgc agcactattt ttattacatt cactcaaaac atattacgcc
     7261 ttgtttcatc tttgttgatg atgttttatc atgcctgcaa agattaaata atcagcattt
     7321 acccgccgta tcctggagtt gtttcgtgtc agatcagatt atcgcccgcg tctcgcaatc
     7381 ccttgccaaa gaacagtcac tggaaagtct ggttcgacag cttctggaga tgctggaaat
     7441 ggtcactgat atggagtcaa cctacctgac caaagtggat gtcgaagcgc gcctgcagca
     7501 tataatgttt gcccgtaata gccagaaaat gcacatcccg gagaatttta ccgtctcgtg
     7561 ggattactcg ttatgcaaac gcgccattga tgaaaactgt tttttcagcg atgaagtccc
     7621 cgaccgttgg ggcgactgta ttgcggcacg caatcttggc atcaccacat ttctgagcac
     7681 gccaattcac ttaccggatg gatcattcta tggcacgctt tgcgccgcca gcagtgagaa
     7741 gcgccagtgg agtgaacgcg cggaacaggt cttacagtta ttcgccggac tgattgcaca
     7801 atatattcaa aaagaggcac tggttgaaca gctgcgcgaa gctaatgctg cgctgattgc
     7861 gcaatcgtat accgactcgt taaccgggct accgaatcgg cgggcgattt ttgaaaatct
     7921 gacgacgctg ttttctctcg cccggcatct taaccataag ataatgatcg cgtttatcga
     7981 tctggataac ttcaaattaa tcaatgatcg ttttggtcat aatagtggcg atctgtttct
     8041 cattcaggtt ggcgagcgcc ttaatacgct ccagcaaaat ggcgaagtta ttggtcgtct
     8101 cggcggtgat gagtttttgg ttgtttcact gaacaacgag aatgcggata tttcgtcgct
     8161 gcgagaacgt attcaacaac aaatacgcgg agaatatcac ttaggtgatg ttgatttgta
     8221 ttatcctggt gccagtcttg gcatagtaga agtcgatcct gaaacgaccg atgcagacag
     8281 tgccctgcat gctgccgata tcgcgatgta tcaggagaaa aaacataaac agaaaacacc
     8341 ttttgtcacg cattcagcgc tacattcctg aggcgtattc acatcctttt gattggtgat
     8401 aacatgcgaa tcggtattat ttttccggtt gtaatcttta ttacagcggt cgtattttta
     8461 gcatggtttt ttattggcgg ctatgctgcc ccgggagcat aaagatgaaa aaaacaacga
     8521 ttattatgat gggtgtggcg attattgtcg tactcggcac tgagctggga tggtggtaac
     8581 gtcacatcta aaaaatagca aaggctgcct gtgtgcagcc tttgtgcaat ttacgcgtta
     8641 acttttaatc ttcctgtaga taaatagcac aacaatcgca ccaataacgg caaccacgaa
     8701 gctgccaaaa ttgaagccat cgactttacc aaagccaaac agcgtgctga tccatccgcc
     8761 gactacggca ccgactatcc ccagcaggat agtcataaag aatccaccac catctttacc
     8821 tggcatgatc cacttcgcca gaataccggc aataagccca aaaataatcc atgacagaat
     8881 gcccattgtt tcctcactta tctgttttgc attagcgggt tagtcgctga taaaaagcat
     8941 agcacaacat cgggagggga agatttgtga cgagcatcac ggaggaattt tttgcgatgg
     9001 cgcagaaatt gcgccatcaa cgatcagtga taattaccaa ccacaaacat catgttcgtt
     9061 ttccgtgtca taagaacgca cggtattcac cagatctttt atcacttcag ccgccacttc
     9121 tggcaccagc aaagtcatcg gcgtctctgt ttcataatcg acagaaacgc cattgctgtt
     9181 attggtgacg gtcacggtat acgttgcttt gcccatgatt catttcccgt tatgaatgac
     9241 tttccgttgt tgcgcgcctt ccatcaggac ttcaggagca acgaagaagt caatgttgaa
     9301 ataagtatcg tcagtcatgg cttcaatgtt gtgccacttt tctggaggga acaccgcaaa
     9361 ctgccccgct tcgataagga tcacctgatc aggctctgca ctgtgttcat cagcgtagcc
     9421 gagatatttg accgccccat gcataacgga aaggcgtggg taaacccccg ggcgcgttcc
     9481 tttatcaaga tgacgttcga atattccggc aggcgcagtt tgtttattcc agaaaggcgt
     9541 tgagcgcgta tgaatataat tctgtgggat ttgcagcatc cttttccctc cttcggtgaa
     9601 tgcgctggaa acggtttatt ccagccgttt cagggtacgc ctgataattt gcattttaaa
     9661 taccatttat tggttacttt ttagcaccgt atcagagaag aatcagggag gattacaggt
     9721 gggaagcccg cggcaacgcg ggctgaaagc atcaggattg cagcgtcgcc agtcgggcgg
     9781 cgaaacccac gaacatcaaa ccaatcagtg agttgcccac tttagccagt ttctttttgg
     9841 tacgtatgta ctgcgtgaca aaagccccag aaataatcag gaagctcaaa tagcagaaac
     9901 tcaccagttc cagcgtcgtc gccagaataa agaatgaaat tcccgtatgt ggggcattaa
     9961 catcgataaa ctgtacgaaa aacgacacat agaacaaaat ggctttcgga ttagtcaggc
    10021 tcaaaattaa cgcgcgttta aaaatggcac cgtattgggg ctcatcggat ttggtctcgc
    10081 tatttttacc tttcagggtc gcgtagagaa ttttactccc cagatagagc aaataaaacg
    10141 caccaagata acgtacgatg ttgaataata tcggggtggt cttaattaat gtcgccactc
    10201 cagcccatgc cagaaacatc aataccgcat cgccaataaa tacaccacag gccgcaagat
    10261 aaccgccttt cataccgcta ctgacgctat ttttgagtac aaacagggta tttggccctg
    10321 gcaccaacac aataaaaatg gccccaacca gataggtcca gtaattcaga accccgtatt
    10381 cagcgaacac attaacctct ttaattatct ttcgatcatg cgcgattaaa ggtgaatatg
    10441 ctaaccaatc tgtagcggct tagaaaggag aaaatcaggt tttaactcga tatcaacccg
    10501 ataattgaat cattaatcag gcatgctcca gtgaaaaatt cgggtagtgc tcggcaaaat
    10561 actggcgtaa aaattctacc gttatccgca ctttcgctga cgtcgacagc tttgaaacat
    10621 aaacggccca gacattcgct ggctggtaat attccggtag cacttgtact aaatgaccac
    10681 tggcgggaaa cagcctggcg acatcgattt ttacgtggtc cggaaaaaca ccgaaggcga
    10741 atattcctcg ccaggcggta gagtgaatga aggaacagag aatgaagtcg tcattcagga
    10801 atcggtattt actcgtcgtg gtgtcgagcg catttggcgt taagctcaaa taagttcatt
    10861 tgaaccgcct gctgttggat ttgtagtttg ccgaagccgg actgagcgcg cccagtccgg
    10921 cttcggaaga ttttactgtg gatattcctg caataaattg tgtaatgctt ccgccatcag
    10981 ctcaccacgc cagccggaaa tcagctccgg caaattgttc tgcggtttca gtttccagtg
    11041 ccagttcagc agttggttga tttgccgacg cgatgccagc aattcggcgc tgatcttgtg
    11101 cgtttcgctg acgtcagtaa tcagcgactt aatcgcttta aacgctttac gataacccgg
    11161 catgtccatc aggttaagca tcggctgcgg taaggcctct tccggcaatg cctgcgcttt
    11221 ttccaccagc gccagcaacg ttttaccgtg gaagcggatt tcgctaccgg ataagcccag
    11281 gctgtccagt tcgcccagac ttcccggcat ataacgcgct accgaccaca aatgctcttc
    11341 acgcacgaca aagttcaccg ccagatcgcg ctctcgcgcc ttgcgcaatc gccagtcggc
    11401 taacagttgc agacaggcca gttggcgtgt gcgtaactgc caggcattgg tgatatcacg
    11461 ccaggcgtct tccggcgcaa cgacttcctg acgacgcatt tgcatcaggc ggcattcatc
    11521 cagcgccgca ggtagccagc cggaggcctc cgtttctacc ataagctttg cggtgatcgg
    11581 taacagatac cagacatccg ccgctgcgta ttcacactga cgttcggtca gcggtctggc
    11641 cagccagtcg gtgcgcgatt cactcttgtc cagcgtaacg ccggaatact cttccaccat
    11701 ggaagcgaaa ccccatgaca tcgggcgtcc gcagaaggca gcaaggattt gcgtgtcaat
    11761 caagggttgt ggtaattcgc caaagacatt gaggaacact tccagatctt cactgcctgc
    11821 atggagaaat tttgtgatgg acggatcgcg caggatcgct ttcagcggtg accagtcggt
    11881 gatcccgagt ggatcgatta gcgccagatg ctcaccatca aaaagttgaa ttaaacccag
    11941 ctgcgggtaa taagtgcgcg tacgaacaaa ttcagtatcc agggctatcg ccggaaaggc
    12001 acggacggct tcacacaaag aagccagcgc atcgtccgtg gtaatcattt ggtaattcaa
    12061 attgtattct ctttagtggg cgtcaaaaaa aacgccggat taaccggcgt ctgacgactg
    12121 acttaacgct caggctttat tgtccacttt gccgcgcgct tcgtcacgta attctcgtcg
    12181 caaaattttt ccgacgttag atttcggtaa ctcatcacga aactccacca gcttcggtac
    12241 tttgtagccc gtgagctgac ggcggcaaaa ggtcaccagt gactcttcgg taagcgatgg
    12301 atcttttttc actacgaaga ttttcaccgc ttcaccactg gagccggaag gtacgccaac
    12361 agccgcgact tcctgtacgc caggatgctg catgacgaca tcttcaatct cgttgggata
    12421 gacgttaaaa ccggaaacca gaatcatatc ttttttacga tcgacaatgc gcaggaatcc
    12481 ttcttcatcc atcaccgcga tgtcgccggt gtgtaaccag ccatttttga tgatttcatc
    12541 ggtagcatcc ggacgctgcc agtaacccag catcacctgc ggtcctttga cacaaagctc
    12601 acctggttga ccaggtggta cttcattatc atcatcatcc accagtttgg cttccgtcga
    12661 cggcaccggc aaaccgatgc taccactatg ataatcaata tcatacgggt taacgctgac
    12721 cagcggcgcg cactcggtca ggccataacc ttccagcaga tactgtccag tcagtttaac
    12781 ccaacgttct gcaaccactt gctgaacagg catcccaccg cctgcggaaa gatgcagact
    12841 ggagaaatcc agctgctgga actctttatt gttcagcaac gcattgaaca aggtgttaac
    12901 gccagtgata gcggtaaacg gatatttcgc taactctttt accagccctg gaatatcgcg
    12961 cgggttagtg ataagcaggt tctgccctcc cagttcgata aacagcaggc agttaatggt
    13021 cagtgcaaaa atgtgataca gcggcagcgc cgtcaccacc agctctttgc ccggatgcaa
    13081 cagcggacca taggtcgcgt taacctgttc caggttcgcc agcatattgc ggtgagtcag
    13141 catcgcgcct ttcgccacac cagtggtgcc gccggtgtat tgcaggaaag ctaaatcttc
    13201 cggcaccaat tctggtttga cgtactgcat ccggtagccg ttgtgcaggg cgctacgaaa
    13261 tgaaatggca tctggcagat ggtatttcgg caccagacgc ttgatgtatt taacaacgaa
    13321 attgactacc gtgccttttg ccgtagatag ctgatcgccc atacgggtca gaataacgtg
    13381 ctgaacggcg gttttatcaa ccactttttc cagagtgtgg gcaaagttag acacgataac
    13441 aatcgccgat gcgccgctat cgttaagctg atgctcaagc tcacgcgggg tatacaacgg
    13501 gttaacgttt acgacgatca tcccggcacg caaaatgcca aacagcgcca ccggatattg
    13561 caataagtta ggcatcatca acgcaacgcg atcgcctttc ttcagcccca acccttgttg
    13621 caaataagcg gcaaacgcgc gactgcgttc ttccagtttg cggaaggtca tcacctcccc
    13681 catattcaca aacgcgggtt gatcggcata gcgtgcgacc gactgctcaa acatatctac
    13741 cagagattga taacggtcag ggttgatctc cgtcggaacg tccgcgggat aacggttaag
    13801 ccaaaccttc ttcaattctt cacctctaaa atgcgtgttc gtcgtcatcg caaccccaag
    13861 tgataaacat gctattaaca taatattaac tcatcttacc agcttgataa ttacccaagg
    13921 aaaaggttgc gaagcgcgtc actatttatt tttatcttta ccgtaagaat gcagaaacag
    13981 cggaccggcc gctgtttctt tttctttaaa aacaagcaat tattcagtta caactgtttg
    14041 tactctcgcg gggccgggat tataccagcc ccatccgccg tagccatagg gccagccacg
    14101 accgccataa aaccatggtt caatcggctg aggcggcata atcacctgct gggttaaatg
    14161 ccaacgtttg taacccgtta cttgcatcac cataaattta tagggcgtat taccgatttt
    14221 gccgtcaacc gcaccggtga ttggcccgac taccgtcacc agttgtccgc ggaaatccac
    14281 cgggtccaga aaaccgttca catcggcata aatgcgaccg cgagaaggtt ctcccagcgt
    14341 cggtctggct ccgctgtcca gtggtacggt ggcaatttcc aggcgggttt tcccttgctg
    14401 gttttgtaca gcaaccactt tgccgccaaa gcgagcctcc tgaccaacgt acagctgcgg
    14461 cgcactcatc acccgaacta aatcttgttg cggcgtggga ctactgcctt taatggcgtc
    14521 cggcacagta acacaaccgc tcagcattag cgcaaacgta cctgccagta tgcctttgat
    14581 aacattcttt tgaaccgcca tgatgcgact cctttttttc tcagggcata ctcttaagat
    14641 tcattctttg cccggaagtt tcttccatgc gacattgtta cgtaaataaa ctggttcggc
    14701 atgttccacc gccaccgttt taccctcggc aaacatctgg cacgcaatcg gcagcatatc
    14761 ttctgcagcg ggcagtaaca cttcgccatc gtgcaaaacc agcccgctct ctttaccgag
    14821 atccggccag gcttgccagc ccgtccctac cgtcacccat tcgccggaaa gctgttgcat
    14881 tcgttcatga accagttcgg gtttgagtac ggcttcggtt tcttcaccgt gccagatacc
    14941 gttttcatca cgctgatatt cggcccagta aacttcgccc attcgcgcgt caatagctgc
    15001 cagcacgcgg gttgcgccgt ttttgcgcca cgccccttgc gccatcgtca ttagcgtgga
    15061 gacgccaatc atcggcagct ctgcgccaag tgccagccct tgcgcaatac caataccaat
    15121 gcgcacgccg gtaaagctac cggggccgcg cccgtaagcc agagcgttta tgtcagtcag
    15181 ggaagttccg ctggtggtca ggatatcctg caccatcggt aagattcgtt gagtatgttc
    15241 acgagggcaa agctcaaaat gagcgttgac agtaccgtcg ttccacaggg cgacagagca
    15301 ggcctctgtc gcggtatcga tagccagaat tcgcatgggt cttcgtgctt agatcaataa
    15361 aaaggcgcgc atcataccat actccgtaac aaattacctg gaggatggta tcgcaaggaa
    15421 acgaaccgca cgggcaatgt cacgggtgcg cggcgctggc ggcagactgg cgagaaacgt
    15481 cgcgccgtaa gggcgcatca ccagccgatt gtcgcaaatc accagcacgc cgcgatcgtc
    15541 ggcgtcgcga atcaatcgcc ctaccccctg cttgagagta atgaccgcat ccggcagttg
    15601 tacttcatcg aacggatcac caccgcgcaa acggcaatct tccatgcgtg cttttaatag
    15661 tggatcatcc ggcgaggtaa acggcaattt gtcgataatc accaatgaca atgtatcgcc
    15721 acgcacgtcc accccttccc agaaactgct ggttgccaca agaagcgcgt taccggcgct
    15781 gacaaattgc tgcaacagtt gccctttgct ggtttccccc tgcaacaaaa cgggaagcgt
    15841 catggtagcg cggaactgct cggccagatc gcgcatcatg gcgtgcgagg tacaaagcat
    15901 aaaacaacga ccgttgttag cttcgatgat cggtcgcagc attgccgcca gttgccgtgc
    15961 ggaacccggt tgattggttt gcggcaggtt gcgcggcaca cagagtaacg cctggcggct
    16021 gtaatcaaag gggctgggta acagcaatga ctctgcctgt tcaatgccaa gccgcgaggt
    16081 gaaatgatgc agatcgtcgt tcaccgacag cgttgctgag gtaaagatcc agctaccggt
    16141 tttttgcgcc attaactctt tgaatttatc cgccacgctg agcggcgtga gagccagagt
    16201 aaaatggcgc gaagtgcatt cgtaccagta gctgtagccc ggctgattga tctcttttag
    16261 ccgtttcagc cgtgtgcgat ataacgtggc gcgctcaaat gccgcatcca gcaaggcgga
    16321 acgccccagc gacagtttcg ccacgtcata acaaagttcc agagtgtcat cgagcagtaa
    16381 aaatgcccgc tgaatttgcg gattagctaa cagctcacgc aggttaccgc gataaccagg
    16441 ctcaccgagt tgcaggcgaa aatcctgcgc actctgggca agacgatccg cgcacttttg
    16501 taactgctgg gtgtctttta attcggtgcg gtaggcgatg gtgatgtctt ttgccaggtc
    16561 gagcagttgt cgactggaga gtgactgacc aaaatactgg ctggcaatgt cgggcagctg
    16621 gtgggcttcg tcgaagatca tgacgtccgc ctccgggatc agttcgccaa aaccgctctc
    16681 tttcaccacc atatccgcca gaaagagatg atggtttacc accaccacat cggcgtccat
    16741 cgcttttttg cgtgctttga ccacaaagca atctttatac atcgggcagt cgctgccgag
    16801 gcagttatcg ttggtgctgg tgaccagcgg ccacgcctgt gaatcttccg ccacgctgac
    16861 gcaggtgctg atatcaccat cgattgtttg attagaccag gagcgcagca ggatcacatc
    16921 gcttaagatt tgtaccggca gatcgccccc cgccaaagcc tgctgttcga gacgttcgag
    16981 gcagaggtag tttgagcgcc ctttcagcag cgccacattg cccgtgtatt tcaatgcctt
    17041 tgagaccgtt ggcaaatcgc ggctgtagag ctgatcctgc aacgcttttg agccggtcga
    17101 gattatgact ttctttttcg cccgcagcgc aggggccagg taagcgtagg ttttgcccgt
    17161 accggttccg gcttccacca ccagcggctg gcctttttct atcgcctggg tgacggctac
    17221 cgccatctgt cgctgtggtt ctcgcggctt aaagcctggt atcgctttcg ccagctgacc
    17281 gtcttgtgca aaatcgtccg tcacactacc ccctgttgat ttgaacaggg attatgtcag
    17341 gatgagggcg ctttcgccag ttgaagtggt gacggcgacc tcacattgtg gcagtctttg
    17401 cagcacgaaa atggaagtat aatgaggaca aaatgatgac tatcgttcgt atcgatgccg
    17461 aagcccgctg gtctgatgtg gtaatccaca acaacacgct ctactacact ggtgtaccgg
    17521 aaaacctcga cgccgatgcc tttgagcaaa ccgccaacac gctggcgcag attgacgccg
    17581 tgctggaaaa acagggcagc aataaatcga gcattctgga tgccaccatt ttcctggccg
    17641 ataaaaacga cttcgcggcg atgaataaag cgtgggatgc ctgggttgtc gcgggtcatg
    17701 cgccggtgcg ctgcacggta caagcaggtt tgatgaaccc gaagtataaa gttgaaatta
    17761 agattgtggc tgcggtgtaa gctttatcga agcaaaataa gtcagacgat aatttatcga
    17821 caatactggt cggttttgca aaaatcgacc agagattaag atattacagt t
//
LOCUS       DAFGPF010000100        17839 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFGPF010000100 DAFGPF010000000
VERSION     DAFGPF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17839
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.100"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..533)
                     /locus_tag="LSX49_003800"
     CDS             complement(<1..533)
                     /locus_tag="LSX49_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL7170157.1"
                     /translation="MKVYNFDKVISRDGTYSAKYNNKGHDIIPLSVADMDIPVADFIV
                     SELSVANQKGIYGYTLLSDDWQQVAAQWYQRHYSWKVNPEHIVFCPRVVQAVSLFIQN
                     FTQPGDAIVSLTPAYHPISHAVEVNHRVLLESALLYRDHHYEIDFADLEDKFKMACCF
                     ILISPHNPTGTIWSEDNL"
     gene            1007..2220
                     /locus_tag="LSX49_003801"
     CDS             join(1007..1298,1298..2220)
                     /locus_tag="LSX49_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558238.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL7170158.1"
                     /translation="MTKKTRFSPEVRQRAVRMVLESQGEYDSQWAAICSIAPKTSCTP
                     ETLRVWVRQYERDTGGGDGGLTTAERQRLKELERENRELRRSNNILRQASAYFGEGGV
                     RPPLEKVMALLDKLREQYGVRPVCSELHIAPSTYYHCQQQRHHPDKRSAHAQRDDWLK
                     REIQRVYDENHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLSGVLRGKKVRTTVS
                     RKTVAAGDRVNRQCVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIVGWRVSSS
                     METTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYG
                     SAMAESINGLYKAEVIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLRHTPPAEAEKA
                     YYASIGNDELAA"
     misc_feature    1288..1404
                     /locus_tag="LSX49_003801"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01497"
     gene            2511..3089
                     /locus_tag="LSX49_003802"
     CDS             2511..3089
                     /locus_tag="LSX49_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004133049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL7170159.1"
                     /translation="MLLPMNTETQHRKKDPIRLYQQLLESAAMIAGRDGIAALSLNAV
                     AREAGVSKGGLLHHFPNKQALIYALFARLLAIMEEAIAALMQKDNISYGRFTRAYVNY
                     LSALTDTQESRQLMVLSLAMPDEPVLRKCWRDWMLGHLANGDELDNSPTGTLVRYTAD
                     GIWLSELTEGITMSPEHRQALVDSLNKMTLPA"
     gene            3112..3930
                     /locus_tag="LSX49_003803"
     CDS             3112..3930
                     /locus_tag="LSX49_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBL7170160.1"
                     /translation="MRYNINARFIYDATDGTLTLPQSTEPDCQLSITSCALLNFFLHH
                     TDIVSREEVLTKVWDNNGLTSSNSNLNQYLSMLRKTFRHYGIDNIIITVARGYLQLNP
                     NVSIEPLDEAPAPPAIIEPSIIPDVDVPTSSEDTESSPPTLAPVTHRHDAYWYFAGAC
                     LLTISILLVAFNLFGISEARPIALTQLSHSQCELLASDEMRRSVSVKAYEKNYDEVRK
                     RLNIACKPSERFLFFYGDRLETNGLGRVFLAHCAMHENNPFSYCDNYFYYSWKL"
     gene            3930..4448
                     /locus_tag="LSX49_003804"
     CDS             3930..4448
                     /locus_tag="LSX49_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004108661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170161.1"
                     /translation="MRIAPRTFFAISALAFIVASGFSFWRLSPAENTGIMSCSTKGIM
                     RFENMEKENVNGNIHFNFGSQGKGSMVLEGYTDSAAGWLYLQRYVKFTYTSKRVSATE
                     RHYRISQWESSASSIDESPDVIFDYFMREMSDSHDGLFLNAQKLNDKAILLSSINSPL
                     WICTLKSGSKLD"
     gene            4968..5246
                     /locus_tag="LSX49_003805"
     CDS             4968..5246
                     /locus_tag="LSX49_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBL7170162.1"
                     /translation="MGDALGLIETKGLVACIAAADAMCKSANVELIGYENIGSGLVTV
                     MVKGDVGAVKASVDSGLESAQHIGEVVTSLVIARPHNDINKIVIKHKA"
     gene            5264..5548
                     /locus_tag="LSX49_003806"
     CDS             5264..5548
                     /locus_tag="LSX49_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002442227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBL7170163.1"
                     /translation="MGDALGLIETKGLVACIEAADAMCKAANVELIGYENVGSGLVTA
                     MVKGDVGAVKAAVDSGVESAQRIGEVVTSLVIARPHNDINKIVSHYKITD"
     gene            5563..5841
                     /locus_tag="LSX49_003807"
     CDS             5563..5841
                     /locus_tag="LSX49_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBL7170164.1"
                     /translation="MREALGLIETKGLVACIEAADAMCKAANVELIGYENVGSGLVTA
                     MVKGDVGAVNAAVDSGVEAARRIGEVVTSRVIARPHNDIEKIASQHKA"
     gene            5895..7481
                     /locus_tag="LSX49_003808"
     CDS             5895..7481
                     /locus_tag="LSX49_003808"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000570989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBL7170165.1"
                     /translation="MIELDTDLRSRQNARVLVRNAKKAQAIMATFSQQQIDAIVKNVA
                     QEAAHHAEALAKMAAEETGFGNWQDKVLKNRFASLRVYDAIKDMKTVGIIHDDQQQKV
                     MDVGVPLGVICALVPSTNPTSTIFYKTLIALKAGNAIIFSPHPGARQCSWKAIEVVKR
                     AAEAAGAPAGIVDGVTELTLEATQELMHSKDVSLILATGGEGMVRAAYASGTPTISGG
                     PGNGPAFIERSADIHHAVKDIITSKTFDNGVICASEQSIIVERCIYNEVHRELEAQGA
                     YFMNEDEAAKMAALLLRPNGTINPKVVGKTALYLSQMAGFCVPASTRVLIAEQTTVSH
                     KNPYSREKLCPVLGLYIEEDWKAACHRVVELLTNEGLGHTLVIHTRNQDVIRQFCLEK
                     PVNRILINTPAALGGIGATTNITPALTLGCGAVGGGSSSDNVGPMNLLNIRKVGYGVR
                     SIDELRSPGSRAEPQPAIAAPIVDPHRSILDDARFTSPAPATTSADDRFTVATTDPEG
                     EINEQNVERVIRQVLERLGK"
     gene            7508..7765
                     /locus_tag="LSX49_003809"
     CDS             7508..7765
                     /locus_tag="LSX49_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBL7170166.1"
                     /translation="MILAKVTGHVVATQKCDELRGSNLLLITQLDDNQQLMKDRSWVA
                     VDSVGAGVHDVVLAEEYFALNKDRYKAMSVVAIVEKVFRDA"
     gene            7781..8935
                     /locus_tag="LSX49_003810"
     CDS             7781..8935
                     /locus_tag="LSX49_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016807796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBL7170167.1"
                     /translation="MSEFLLKPRICFGQDALSVLDELTACHVLLVTDQAMVKFGLAER
                     VTQRLCARGIDWQVWDDVVADPDIATVVRGMKLMDSCYPDLVIALGGGSVIDAAKAVI
                     FALAQTRPEAGRERPCFVAIPTTSGTGSEVTSFSVVKAHAEKLVLVDSSLLPDIAILD
                     PSLVASVPPAITADTGMDVLCHALEAYVSLAASDFSDALAEKVVQQVFSYLPGCWRNG
                     QDLQAREKMHNASCMAGMAFTNASLGITHSLAHALGGVFRVPHGRANALLMAHVVAWN
                     ADYHGQCDTLAARKYARLAHLLDLPASTPREGVTSLLVAIQTLKDEMNMPRGINDTGV
                     NAADFDQRLAEMVAQALRDSCTPTNPREPDARALTELYRQAWSGNIAQCH"
     gene            8962..12348
                     /gene="cutC"
                     /locus_tag="LSX49_003811"
     CDS             8962..12348
                     /gene="cutC"
                     /locus_tag="LSX49_003811"
                     /EC_number="4.3.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004182805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline trimethylamine-lyase"
                     /protein_id="HBL7170168.1"
                     /translation="MANYNLTPRVKVLAERLLAHPSTLCVEHAGILSGLDGDIAGIPA
                     AVKPARRFYELMRQLPLAVSPDELIVGNQTHRPHGAIFHDESTAHRPSVFQFLNLNSD
                     LDAPDYKLVIEKGVLAIKQQLEEKTRSLGSAVSRSGMDEVNACRAAIYACDALMQLAQ
                     NLATSAEKLAATETNAYRKAELSESAAILHHIPARPARSFKEACQAFYLFQLALQLDN
                     GSYAVNPEGADKALLAYYQHDIANGLLTEAQAYEIVECLWFKLAELSEVRAACAIDGY
                     PMFDALLHGASLENAVINPLSEMFLNAQRNLSALNLPIRLFHGAHKTVTTLCAACNET
                     PVLEGLTPRIQRLRNHYLTVRPSVSIYRALAFTEVVKANPGMPTILLRAKAFRHACET
                     APILIQDDELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMSTRPQDPFEISEEDKKTI
                     REEIVPFWEGRSLDEICEAQYREAGVWSFSGETFVSDLSYHQVNGGGDTCPGYDVLLF
                     TKGMNGIKADAEAHLAELSMENPEDIDRIYYYKAAIDTCEGVINYAHRIAARARELAA
                     VEQNAQRRAELLTIAEVNQNVPANPPKTLQEALQSIWTVESLFEIEENQTGLSLGRVD
                     QYCYPMFEADIREGRLTHEGALELMQAFIIKCAELMWMSSELGAKYFAGYQPFINLTV
                     GGQKRSGGDACNDLTYLIMDAVRFVKVYQPSLACRIHNQSPQKYMEKIVDVVKAGMGF
                     PACHFDDSHIKMMLRKGFDFEDARDYCLMGCVEPQKSGRIYQWTSTGYTQWPIAIEFV
                     LNRGRMVLFDSYQGLDTGDLKDLRTFEDFDAAVKKQVAHIIRLSAIGTVISQRVHRDV
                     APKPLMSLLVEGCMEKGKDVSAGGAMVNHGPGLIFSGLATYVDSMAAIRKLVYEDKKY
                     TLEQIRDALLANFEGYEGLRRDCLNAPKYGNDDNYVDQYALDITEWTERECRKYKMLY
                     STLSHGTLSISNNTPIGELTNATPNGRLAWMPLSDGISPTQGADKHGPTAIIKSVSKM
                     NVETMNIGMVHNFKFLKGLLDTPEGRHGLITLLRTASILGNGQMQFSYVDNEVLKKAQ
                     QEPEKYRDLIVRVAGYSAYFVELCKEVQDEIISRTVIEKF"
     gene            12400..13347
                     /gene="cutD"
                     /locus_tag="LSX49_003812"
     CDS             12400..13347
                     /gene="cutD"
                     /locus_tag="LSX49_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020316596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline TMA-lyase-activating enzyme"
                     /protein_id="HBL7170169.1"
                     /translation="MSANKELSGRIFNIQKYSIYDGDGIRTLIFFKGCNLRCPWCANP
                     EGLSSQFQVMFSQDKCINCGDCVNVCPAGIHYRAEVNGEMKHFVNRNKDCIGCRKCEE
                     ICTQNALDIMGKDVTVSELMEIIMQDYDFYVSSGGGVTIGGGEMSLQTDFAVALFSEC
                     KKMMINTAVETQGTTPLANYQKLAPVTDTFLFDIKQIDSNHHKTLFGIGNEGVRRNLE
                     WLVDSGANVIVRMPLIRGYNDSWEAITGAIDYVQKLAKRGNIRRIDILPYHQLGRKKY
                     ERLEMPYPIVEDPSYSVEELDKLEAFFAQFDFDIRLVRH"
     gene            13359..13823
                     /locus_tag="LSX49_003813"
     CDS             13359..13823
                     /locus_tag="LSX49_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBL7170170.1"
                     /translation="MNSLGVIETRGLVAAIQAVDAACKAAGVTCIGYRKVGSGLVTVC
                     FDGEISAVYTAIERGIAVASATDHQAKSLVIARPERCVVEALSNLKGHPPRVESGQKP
                     HAELPTVAEMAVCEETAEVSTDTETAMPVPEKEVQAPIVEVKSHGHKKGKKA"
     gene            13820..14440
                     /locus_tag="LSX49_003814"
     CDS             13820..14440
                     /locus_tag="LSX49_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBL7170171.1"
                     /translation="MIDALLQEKITTRLIDTAPTIPVGVSNRHVHLSQQDVEALFGVG
                     YQLTPFKPLRQPGQFAAEECVTVVGPKGSLTHVRVLGPVRPTSQLEISRADCFTLGIK
                     APVRESGQLENAGDALLVGPKGHVELHSQVICAWRHIHMSPQDARLLNVSNGQKVSVR
                     SHGERQLTFDEVVVRVRNDFALELHIDTEEANAAGLKNGAQVTLIR"
     gene            14452..15117
                     /locus_tag="LSX49_003815"
     CDS             14452..15117
                     /locus_tag="LSX49_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170172.1"
                     /translation="MTEQQIDTIVNLILQRLQPAVLVMVTSADGYRDLIHQRLARCGE
                     RLHLALDETISDSERWQQIGDVIPAKTWQHKLPSTPYKALLLPFLSYPLAVDIVNGTL
                     QSPVAQRVHDALLAGIPVLALRYYCDPHSELNALRGTVHSDYAAHLSATLTGLSECGI
                     TLCSMNEMLEKLATDVSSQSPVSHHRRYLTVTDIVNNPALAKSPDAVLTDAAVDFLKA
                     QKK"
     gene            15150..15551
                     /locus_tag="LSX49_003816"
     CDS             15150..15551
                     /locus_tag="LSX49_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012542991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL7170173.1"
                     /translation="MSSKTKCWLWMLLVILSETSATSTLKMFDNSEGMTKTLLLALIV
                     VLYCICYYSLSRAVKDIPVGLAYATWSGTGILMVSTLGILFYGQHPDTAAIIGMVIIA
                     SGIIIMNLFSKMGSEEAEETPVTNLDKKIAN"
     gene            15567..15896
                     /locus_tag="LSX49_003817"
     CDS             15567..15896
                     /locus_tag="LSX49_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011705235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL7170174.1"
                     /translation="MFNIGFLWLALSIGSEITGTSMIKKTNGFRRLWPSVLVVCAYST
                     CYFALTRAMSTIPVGVAYSLWCGFGIVGVTIFSMILYKQKPDLPAIFSMLLIISGGII
                     MNVFSNM"
     gene            complement(16120..16442)
                     /locus_tag="LSX49_003818"
                     /pseudo
     CDS             complement(16120..16442)
                     /locus_tag="LSX49_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16559..17503)
                     /gene="dsdC"
                     /locus_tag="LSX49_003819"
     CDS             complement(16559..17503)
                     /gene="dsdC"
                     /locus_tag="LSX49_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DsdC"
                     /protein_id="HBL7170175.1"
                     /translation="MEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPS
                     AVSHRINQLEEELGIQLFVRSHRKVELTHEGKRVYWALKSSLDTLNQEILDIKNQELS
                     GTLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDDAP
                     SAQLTHHFLMDEEILPVCSPEYAQRHALTNQVINLRHCTLLHDRQAWSNDSGTDEWHS
                     WAQHYAVNLPTSSGIGFDRSDLAVIAAMNHIGVAMGRKRLVQKRLISGELVAPFGDMT
                     VKCHQHYYITTLPGRQWPKIEAFITWLREQVCQSCQYQ"
     gene            17721..>17839
                     /locus_tag="LSX49_003820"
     CDS             17721..>17839
                     /locus_tag="LSX49_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170176.1"
                     /translation="MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFV"
BASE COUNT         4495 a         4395 c         4550 g         4399 t
ORIGIN      
        1 agattgtctt ctgaccagat tgttcctgtt ggattatgcg gcgatattag aatgaaacaa
       61 caagccattt taaacttatc ttcgagatcc gcaaagtcta tttcatagtg gtggtcacga
      121 taaagtaacg cactttccag caatactcga tggttgactt caactgcatg actaatagga
      181 tgataggctg gtgtcaggct gacaatagca tctcccggtt gggtaaagtt ctggataaat
      241 aatgagacgg cctgtactac ccgtgggcaa aaaacaatgt gttcagggtt gaccttccac
      301 gagtaatggc gttgatacca ctgtgctgcc acttgctgcc agtcatcact taataatgta
      361 taaccgtaga tacctttctg atttgcgaca gataattcag aaactataaa atcagctaca
      421 ggaatatcca tatcagctac agacagagga atgatgtcat gccccttgtt attatattta
      481 gcgctatagg ttccgtcgcg tgaaataact ttatcaaaat tataaacttt catatttgtt
      541 actcgcccga ttttatcgtt agggtaacgt aatatatcga gggaggaagt gttattctgt
      601 attttgtttt cgttattatg aaaatttgca tatgtgatgt ttatcacaaa gatgttaact
      661 atctgtcaat aaaaagactc cagcaaatgt aaacgtttta catcgcttaa gcctatggaa
      721 tttacataaa aaaaagggcg tgccgagtct ttcgacccaa tcattatctc ggtaactcca
      781 ttcacaagag caggaaataa ccccttcaac aaataacaga ctgatgcctg cgagcgcgct
      841 ccccaggttt ccgggctgaa agtaccgccg cactcgttta acgcggaaca gtctgtgttg
      901 gcggtttaat ggtggatgtt gctgtagacc acaactgatg aggcaacgga gttgaaccgc
      961 cccggaaatc ctggagacta aacttcctga gaaagaggta aacaggatga ctaaaaaaac
     1021 acgtttttcc cccgaagtcc gtcaacgggc agttcgtatg gttctggaaa gtcagggcga
     1081 atatgactca caatgggcgg caatttgttc cattgctcca aagactagct gtacgccgga
     1141 gactctgcgt gtctgggttc gccagtatga gcgggatacc ggaggcggtg atggtgggct
     1201 taccaccgct gaacgtcagc gtctgaaaga gctggaacgt gaaaatcgtg aactgcgccg
     1261 cagtaacaat atccttcgcc aggcttccgc ttattttgcg aaggcggagt tcgaccgcct
     1321 ctggaaaaag tgatggcact gctggataag ctgcgtgagc agtacggggt cagaccggta
     1381 tgcagtgaac tgcatattgc cccgtcaacg tattaccact gtcagcaaca gcgacatcat
     1441 cctgataaac gcagtgcaca tgcacagcgc gatgactggc tgaagagaga gatacagcgc
     1501 gtatacgatg aaaatcatca ggtgtacggt gtgcgtaaag tctggcgtca gttgttacgg
     1561 gaaggaatca gggtggccag atgtacagtg gcgcgcctca tggcggttat gggactttcc
     1621 ggtgttctcc ggggtaaaaa ggtccgcact accgtcagcc ggaaaaccgt tgccgcaggt
     1681 gaccgcgtaa accgtcagtg cgtggcagaa cgtcctgacc agctgtgggt ggctgatttt
     1741 acttacgtca gcacatggca gggcttcgtc tatgtggcgt tcatcattga tgtgtttgcc
     1801 ggatacatcg tggggtggcg ggtatcatcg tccatggaaa cgacattcgt gctggatgcg
     1861 ctggagcagg cgttgtgggc ccgtcgtccg tccggcacca tccatcacag cgataaaggc
     1921 tctcagtatg tgtcactggc ctatacggag cgattaaaag aagcaaaact gctggcatca
     1981 acagggagta caggcgactc gtatggcagc gcgatggcgg agagcatcaa tggtctttac
     2041 aaagcggagg taatacaccg taagagctgg aaaaaccgtg cagaagtgga actggccaca
     2101 ctcacgtggg tggactggta taacaatcga cgattgctgg gaaggctgag gcatactcct
     2161 ccggcagaag cagaaaaagc gtattatgct tctatcggaa atgatgagct ggcagcctga
     2221 gttcacagat aaaacactct ctaggaaccc cggggcggtt cattctcgct tgccttctgt
     2281 atttcaaaaa gcatcattca ggtcattaaa agttatttga tcatcttttt atggattttc
     2341 tgttcatcga aagggtaaca gattcccacc attgtgcaga ccaggagaat taacagcagc
     2401 agtaggattt atacgacaaa ttgtgacctc acacgcaata cccatactca cttcatgggt
     2461 agctgcttct ccttgatagc gatcaaaaaa aaacataccg tctggtcggt atgcttctgc
     2521 ctatgaatac agaaacccaa catcgtaaaa aagatcccat ccgtctgtat cagcagttgc
     2581 tggagtctgc agctatgatt gctggtcgtg acggtatcgc tgccctctcg ctgaatgcgg
     2641 ttgcccgcga agctggcgtg agtaaaggtg gattactgca tcactttccg aacaagcagg
     2701 cgctgatcta cgccttgttt gcccggttgt tggcaataat ggaagaggcc atcgctgccc
     2761 tgatgcaaaa agacaatata agctatggcc gttttactcg cgcatatgtg aactatcttt
     2821 ctgcgctgac tgacacacaa gaaagccgtc aattgatggt gctttcgctg gcaatgcccg
     2881 atgaaccggt gctgcgaaaa tgctggcgag actggatgct tggtcattta gcgaatggcg
     2941 atgaactgga taatagccca accggaacgc tggtgcgcta taccgcagat ggcatctggt
     3001 tgtctgagtt aacggaaggg atcaccatga gccccgaaca tcgtcaggca ctggttgatt
     3061 cactgaataa gatgacactt cccgcgtgaa gtcccatgga ttgaggtcgc gatgcgctat
     3121 aacatcaatg cccgtttcat ttatgacgct acggatggca cgcttacgct accgcaaagc
     3181 actgagccag actgccaact ctcgataacg tcctgcgcgc tgctcaactt ttttttgcat
     3241 cataccgata tcgttagtcg cgaagaggta ctgacaaaag tttgggataa caacggatta
     3301 acttcttcta acagcaatct gaatcagtat ctcagtatgc tgcgcaagac gttccgtcac
     3361 tatggtattg ataatattat cattaccgtt gcacgcggct atctgcagct aaacccgaat
     3421 gtatccatcg aaccactgga tgaagcccct gcgccacctg caattataga gccatccata
     3481 atccctgatg ttgacgtacc aacatccagt gaggataccg agtcttcacc accaacatta
     3541 gcgccagtca cccatcgtca cgacgcttac tggtattttg caggtgcctg tttgttaacc
     3601 atttcgattc tgttggtagc cttcaatttg ttcggtatca gcgaggcgcg ccccatcgct
     3661 ttgacgcaac tttctcatag ccagtgcgaa ttactggcaa gcgacgaaat gcgccgttca
     3721 gtaagcgtga aggcatatga gaaaaattat gacgaagtcc gtaagcgtct aaatatcgcc
     3781 tgtaaaccaa gtgagcgttt tctttttttc tacggtgaca ggctggaaac caacggcctt
     3841 gggcgagtgt tcctcgcgca ctgcgctatg catgaaaata acccgtttag ttattgcgat
     3901 aactactttt attactcttg gaaactgtaa tgagaatcgc accgcgtacc ttctttgcta
     3961 tttccgccct ggcgtttatt gtcgcctccg gatttagttt ctggcggttg tcccctgctg
     4021 aaaatacagg gattatgagt tgttcaacaa aaggcatcat gcgttttgag aatatggaaa
     4081 aggagaacgt taacggtaat attcacttta actttggcag ccagggtaaa ggttcgatgg
     4141 tgctcgaagg ctacacggac tctgccgctg gctggctgta cctgcaacgc tatgtcaaat
     4201 ttacctatac cagtaaacgt gtttccgcca cggaacgcca ttaccgcatc agccagtggg
     4261 aatccagcgc ctcatcgata gatgaatcac cagatgtgat ttttgactac tttatgcgtg
     4321 aaatgtctga cagccatgac gggctgttcc tcaacgccca gaagctgaac gataaagcga
     4381 ttttgctcag ttctattaat tcaccgcttt ggatctgtac ccttaaatct ggcagcaaat
     4441 tagactagtt ttttctggct gccttacgca acgaattgct caccactttc atcgtccccc
     4501 cttcgcctga cgagaaacac gactctttaa cttcgtgata gcacaggcga tttgtgatgt
     4561 accacgcatt ccattttccc cttctcaacg gccctgagca aaagcgcatt ttttgcgttt
     4621 agggtttgcg ccaaagtatg agccccaaca cacttcaccg ctgtagctgt tacccccttt
     4681 tcgtaattat ttagcaactt agcaacaaac atacccggcg aaaaaaatac gccaaaaagc
     4741 gcattattaa aaacaaaatc ctccccacca ctccagcaca aatacataaa tcagagtgta
     4801 ttgaaagcta aatttcagaa tttaattcta aatcattgct gtcagcagat ttaaattcca
     4861 caaaattcca tgagctctat agtgacattc gaacgccgct tccgtgagtt aacgctgtgt
     4921 cacggacggt tttcctgaat cacaaaacct gttctgagga gatcaccatg ggtgatgcat
     4981 tagggcttat cgaaaccaaa ggcctggtgg cctgtattgc cgcagcggat gcgatgtgta
     5041 aatccgccaa cgttgaactg attggctatg aaaacatcgg ctctggtctg gtgaccgtga
     5101 tggtgaaagg cgacgttggc gcagtgaaag catctgtcga ttctggactt gagtccgcac
     5161 agcacatcgg ggaagtggtg acgtcgctgg ttatcgcgcg tcctcacaac gacatcaaca
     5221 aaatcgttat taaacataaa gcttaaggcc ggagggaaga aacatgggtg atgcattagg
     5281 tctgattgaa accaaaggtt tggtggcttg tattgaagca gctgacgcga tgtgtaaggc
     5341 cgccaacgtt gagttgattg gctatgaaaa cgtcggttct ggtctggtta ccgcaatggt
     5401 gaaaggtgat gtcggcgcag taaaagcggc ggtggattcc ggtgttgagt ccgcacagcg
     5461 cattggcgag gtggtgacgt cgttggttat cgcgcgtcca cacaatgaca tcaacaagat
     5521 tgtctcgcac tacaaaatta ccgattaacc ggagaaaaca taatgagaga agcgcttggt
     5581 ctgatcgaaa ccaaaggtct ggtggcctgt attgaggcgg cagacgcgat gtgtaaagcc
     5641 gccaacgttg agttgattgg ctatgaaaac gtcggctctg gcctagtcac cgcgatggta
     5701 aaaggcgacg ttggcgcagt gaatgccgcg gtggattccg gtgttgaagc agcaagacgt
     5761 atcggtgaag tggtgacctc ccgtgtcatc gcccgcccgc ataacgacat cgaaaaaatc
     5821 gcgtcgcagc ataaagcatg acctgacagg gcacgccccg tctgcactct tttagtctga
     5881 tgaaggatag actcatgatt gaactggata ccgatttgcg ctcccgtcag aacgcgcggg
     5941 tgctggtgcg taacgccaaa aaagcgcaag cgattatggc cactttttcg cagcagcaaa
     6001 tcgacgccat cgtgaaaaac gtggcccagg aagcagcaca ccacgctgaa gcactggcaa
     6061 aaatggccgc agaagaaact ggcttcggca actggcagga taaagtcctg aaaaaccgtt
     6121 tcgcctcgct gcgtgtttac gatgccatca aagatatgaa gaccgtcggc atcattcatg
     6181 acgatcaaca gcaaaaagtg atggacgtgg gcgtgccgct gggtgtgatt tgcgccctgg
     6241 tgccgtcaac caacccgact tccaccatct tctacaaaac gctgatcgcc ctgaaagccg
     6301 gtaatgcgat tattttctct ccgcatcccg gcgcacgtca gtgtagctgg aaggcgatag
     6361 aagtcgttaa gcgtgccgca gaagctgctg gtgcacctgc gggtattgtc gatggtgtaa
     6421 ccgagctcac gctggaagca acccaggaac tgatgcatag caaagatgtt tcgctgattc
     6481 tggctaccgg tggtgaagga atggtacgag cagcatatgc ttctggcaca ccgaccatca
     6541 gcggtggtcc tggtaacggt ccggcattta ttgaacgcag tgcggatatc caccatgcgg
     6601 tgaaagatat catcaccagc aaaaccttcg ataatggtgt gatctgcgct tctgaacagt
     6661 cgattattgt tgaacgctgc atttacaacg aagtacaccg cgaactggaa gctcagggtg
     6721 cttactttat gaacgaagat gaagcggcaa aaatggcagc tctgctgctg cgcccgaacg
     6781 gcacgattaa cccgaaagtg gtgggaaaaa ccgcactgta tttaagccag atggccggtt
     6841 tttgtgtgcc cgccagtacc agagtactga ttgccgaaca aactaccgtt tctcacaaaa
     6901 acccctactc acgtgaaaag ctgtgcccgg ttcttggtct gtatatcgaa gaggactgga
     6961 aagctgcctg ccaccgcgtg gtggagttgc tgactaacga aggtctgggc cacacactgg
     7021 tgatccatac ccgcaaccag gatgtgatcc gtcaattctg ccttgaaaaa ccggttaacc
     7081 gcattctgat caatacccct gcggcgcttg gcggtattgg cgctaccact aacattaccc
     7141 ccgccctgac gcttggatgc ggtgcggtag gtggtggttc ctcttccgat aacgtcgggc
     7201 caatgaatct gctcaacatt cgtaaagtgg gctatggcgt gcgttccatc gatgagttgc
     7261 gttctccggg tagccgtgca gaaccgcagc cagccatcgc cgcgccgata gtggatccgc
     7321 atcgcagcat tcttgacgat gcccgcttca cctcccctgc cccggcaacc acatctgctg
     7381 atgatcgttt tactgtggca acgactgatc ccgaaggcga gatcaacgag cagaacgttg
     7441 agcgagtcat ccgccaggtg cttgagcgct taggcaagta attcattgag ataaggcgat
     7501 aaaaacgatg attctcgcaa aggtaaccgg acatgtcgtc gccacgcaaa agtgcgatga
     7561 gctgcgcggc agcaacctgt tgttgatcac ccaactggat gataaccaac agctgatgaa
     7621 ggaccgctcc tgggtcgctg tcgatagcgt cggtgcaggc gttcatgacg ttgtgctggc
     7681 ggaggagtac ttcgcactca ataaagatcg ttacaaagcg atgtcagtgg tcgccattgt
     7741 cgagaaggtt tttcgggacg cttaaggagt gaaaaaacca atgagtgagt ttttgctgaa
     7801 accccggatc tgcttcggtc aagacgcgct gtcagtcctg gacgagctaa ccgcctgtca
     7861 tgttttgctg gttaccgatc aggcgatggt caaattcggt cttgctgaac gtgtcacgca
     7921 gcgtctctgt gcgcgcggca ttgactggca ggtgtgggat gacgttgtcg ccgatccgga
     7981 tatcgctacc gtggtccgag ggatgaagtt gatggacagc tgctacccgg atctggttat
     8041 cgcactcggc ggtggttcgg tcattgacgc agccaaagcg gttattttcg ccctggcgca
     8101 aacccgtccg gaagcaggac gtgaacgccc ctgctttgtg gctattccaa ccaccagcgg
     8161 tacgggctca gaagtgacca gtttctcggt ggtgaaagcc catgccgaaa aactggtgct
     8221 ggttgactcg tcgctgctac cggatatcgc cattcttgat ccgtcactgg tggcatccgt
     8281 gccacctgct atcaccgctg acaccggaat ggatgtgttg tgccacgctc tggaggctta
     8341 tgtctccctt gccgccagcg acttttccga tgcacttgct gaaaaagtgg tgcaacaggt
     8401 gttcagctac ctgccgggct gctggcgtaa cggccaggat ttgcaggctc gggagaaaat
     8461 gcacaacgcc tcatgtatgg caggaatggc gtttaccaat gcctctcttg gcatcaccca
     8521 tagcctggct catgcccttg gtggtgtttt ccgtgtccct catgggcgcg caaatgccct
     8581 gctaatggca cacgttgtgg catggaatgc tgactaccac ggtcaatgcg acacccttgc
     8641 tgcgcggaaa tatgcacgtc tggcacatct gttggatctg cctgccagca cgcctcgtga
     8701 aggagtaaca agcctgctgg tcgcaatcca aacgctgaaa gatgaaatga atatgcccag
     8761 ggggattaac gacaccggcg tgaatgccgc tgatttcgat cagcgcctgg cggagatggt
     8821 tgcccaggca ctgcgtgaca gttgcacccc aaccaacccg cgcgaaccgg atgcccgcgc
     8881 cctgactgaa ctttatcgcc aggcctggag cggcaatatc gctcaatgcc actgataaca
     8941 agaactggag acccttacct tatggcaaac tacaatttaa caccgcgcgt aaaagtgctg
     9001 gctgaacgtt tactggctca ccccagtacc ctgtgcgttg aacatgccgg gatcctgagt
     9061 gggctggatg gtgatatcgc gggcattccc gccgcagtaa aacccgctcg ccgtttctat
     9121 gaactgatgc gccagctacc gctcgctgtt agccccgatg aactgattgt tggcaatcag
     9181 actcatcgtc cgcatggtgc gattttccac gacgaaagta cggcccaccg cccgtctgtt
     9241 tttcagtttc ttaatctaaa tagcgacctt gatgccccgg attataaact ggtgatcgaa
     9301 aaaggcgtgc tggcaatcaa acagcaattg gaagagaaaa cccgctcact gggcagcgcc
     9361 gttagccgca gtggtatgga tgaagtcaac gcttgccgcg ccgcgattta tgcctgtgat
     9421 gccctgatgc agttagcgca aaatctggcc accagcgccg aaaaactggc tgcaactgag
     9481 acaaatgcgt atcgcaaagc tgagttatct gaaagtgccg ccattttgca ccatatccca
     9541 gcgcgtcctg ctcgtagttt taaagaggct tgccaggcat tttatctgtt ccagttagca
     9601 ctccagttag ataatggtag ctatgctgtt aacccggaag gcgcagataa agcgctgctg
     9661 gcgtattatc agcatgatat tgccaacggt ctgctgaccg aggcgcaggc ttacgaaatt
     9721 gtcgaatgtt tgtggtttaa actggcagaa ctgagtgaag tccgcgcagc ttgtgctatc
     9781 gatggctacc cgatgttcga tgctctgttg cacggtgcaa gccttgagaa cgcagtgatt
     9841 aaccctcttt cagagatgtt cctcaatgca caacgtaacc tgagcgcgct aaatctgccc
     9901 atacgtctgt tccatggcgc ccacaaaacc gttaccacac tatgtgccgc ctgtaacgaa
     9961 acgccagtgc tggaaggcct gacaccacgt atccaacgtc tgcgtaacca ctacctgact
    10021 gtccgcccga gtgtttctat ttaccgtgca ctggctttta ccgaagtagt gaaagcgaat
    10081 ccaggaatgc caaccatcct gctgcgtgct aaagcgttcc gtcacgcctg tgaaactgcg
    10141 ccgattttga ttcaggacga tgagctgatc gtcggtcatc cttgcggtaa accgcgtgct
    10201 ggcgcatttt cacctgatat tgcctggcgc tgggtgcgtg acgaactcga taccatgagt
    10261 actcgcccgc aggatccgtt tgaaatcagc gaagaagata aaaaaaccat tcgcgaagag
    10321 attgtaccgt tctgggaggg gcgctcgctg gatgaaattt gtgaagcaca ataccgcgaa
    10381 gctggcgttt ggtcgttcag tggcgaaaca ttcgtcagcg acctctccta tcatcaggtt
    10441 aacggtgggg gtgatacctg tccgggctac gatgtgctgc tgtttaccaa agggatgaat
    10501 ggcatcaaag ccgatgccga ggcgcatctt gccgaactga gcatggaaaa cccggaagat
    10561 atcgatcgca tttactacta caaagcagcg atcgacacct gtgaaggggt gatcaactat
    10621 gcgcatcgta ttgccgcccg tgcccgtgaa ctggctgccg ttgaacagaa cgcccagcgt
    10681 cgagcagagc tactgactat cgcagaagtt aaccagaacg ttccggcgaa tccgccgaaa
    10741 accttgcagg aagcgctgca aagtatctgg acggtagagt cactgtttga gattgaagag
    10801 aaccagacag gcctgtcact tgggcgtgtt gaccagtact gctacccgat gtttgaagca
    10861 gatatccgtg aaggtcgcct gactcatgaa ggtgcactgg agctgatgca ggcatttatc
    10921 atcaaatgtg ccgagctgat gtggatgtcc agcgaactgg gagcgaaata ttttgcgggt
    10981 tatcagccat ttatcaacct gactgtcggt ggtcaaaaac gtagcggtgg cgatgcctgc
    11041 aacgatctca cctatctgat tatggatgca gtccgttttg tgaaagtgta tcagccatca
    11101 ctggcttgcc gtatccataa ccagtcgccg caaaaatata tggaaaaaat tgtcgatgtg
    11161 gtgaaagcgg ggatgggctt cccagcctgt cacttcgatg actcccatat caaaatgatg
    11221 ctgcgcaaag gctttgactt tgaagatgcc cgtgattact gcctgatggg ctgcgtggaa
    11281 ccacaaaaat caggtcgtat ttaccagtgg acttccaccg gctacaccca atggccaatt
    11341 gccatcgagt ttgtcctcaa ccgtggtcgt atggtgctgt ttgatagcta tcaggggctg
    11401 gacacgggcg atctgaaaga tctgcgcaca ttcgaagatt ttgatgccgc ggtgaaaaaa
    11461 caagttgctc atatcatacg cttgtccgcc atcggtacgg tcatcagcca gcgtgtgcac
    11521 cgggacgtgg caccaaaacc gctgatgtcg ctactggttg aaggctgcat ggaaaaaggc
    11581 aaagacgtct ctgccggtgg cgcaatggta aaccacggac ctgggctgat tttctctggt
    11641 ctggctacct acgtcgattc aatggcggcc atccgcaaac tggtttacga agataagaaa
    11701 tatacccttg aacagatacg ggacgctctg ctggcaaact ttgaaggtta tgaaggcttg
    11761 cgtcgcgact gtctgaacgc accgaaatac ggcaacgacg ataactacgt tgaccagtac
    11821 gctctggata tcaccgagtg gactgaacgt gaatgccgca agtacaagat gctctactcc
    11881 accctcagcc acggtacgtt gtcgatctcc aacaatacgc cgattggtga gctgaccaat
    11941 gccacaccaa atggtcgtct ggcgtggatg ccgctttctg acgggatcag cccgactcaa
    12001 ggggcggata agcatggccc aacggcgatt atcaagtctg tgagcaaaat gaacgttgaa
    12061 accatgaata tcggcatggt gcataacttc aaattcctca aagggttact tgatacacct
    12121 gaaggacgcc acggcctgat aactctactg cgtacagcat caattctcgg caacggtcag
    12181 atgcagttca gctacgtcga taacgaagta ctgaaaaaag cacaacagga accggaaaaa
    12241 taccgtgatt tgatcgtccg tgtagccggt tacagcgcct acttcgtgga attgtgcaag
    12301 gaagttcagg acgaaatcat cagccgtacg gtgattgaga agttctgata agacggatcg
    12361 caaccggaca aggatgtccg acattttcag gaggcaagcg tgagcgcaaa taaagaatta
    12421 agcggacgaa ttttcaatat ccagaaatat tcgatctacg acggtgacgg tatccgcaca
    12481 ctgatttttt ttaaaggctg caatcttcgc tgcccgtggt gtgccaaccc ggaagggtta
    12541 agcagccagt ttcaggtgat gttctctcag gataaatgca tcaactgcgg cgactgcgtc
    12601 aatgtatgcc ctgcggggat ccactaccgc gcggaagtca acggagaaat gaagcatttc
    12661 gtcaaccgta ataaagactg cattggttgt cgcaagtgtg aagaaatttg cacccaaaat
    12721 gcactggata tcatgggtaa agatgtcacg gtcagtgaat tgatggagat catcatgcag
    12781 gactatgact tttacgtctc ctccggcggt ggtgtcacta ttgggggcgg tgagatgagc
    12841 ttgcaaactg attttgccgt tgccctgttc agtgaatgca aaaagatgat gatcaacacc
    12901 gccgtcgaga cccagggtac aaccccgctt gcaaactatc agaagctggc tccggtcacc
    12961 gacaccttcc tgttcgatat caaacagatc gatagcaatc accataaaac gctgttcgga
    13021 attggcaacg aaggcgtgcg tcgcaatctg gagtggctgg tggattcggg ggccaacgtg
    13081 attgttcgta tgccgctgat tcgtggttat aacgattcgt gggaagcgat taccggcgct
    13141 atcgactacg tccagaaact ggccaaacgc ggcaatattc gccgaatcga tatactgccg
    13201 taccaccagc tggggcgcaa aaagtatgaa cgactggaga tgccctaccc gattgttgaa
    13261 gacccgtcat acagcgtgga agagctggac aaactggagg cgtttttcgc ccagttcgat
    13321 tttgatattc gcttagttcg tcattaaagg agccgtaaat gaacagttta ggcgtaattg
    13381 aaacacgtgg tcttgtagcc gcaatccagg ccgtagatgc cgcctgcaaa gcagccgggg
    13441 tgacctgtat tggttatcgc aaagtaggtt ccgggctggt aaccgtctgt tttgatgggg
    13501 aaatcagcgc agtttacacg gccattgaac gtggtattgc tgtggcatcc gcaaccgacc
    13561 atcaggccaa atcactggtg atcgctcgcc cggaacgctg cgtggttgag gctctcagca
    13621 acctgaaagg tcatccgcca cgtgtcgaat caggccagaa acctcatgca gagctgccga
    13681 cagttgcaga aatggctgtc tgcgaggaaa ccgctgaagt ttctacagat actgaaactg
    13741 caatgcctgt acctgagaaa gaagtgcaag cccccatcgt ggaagtgaaa agccacgggc
    13801 ataagaaagg gaagaaagca tgattgacgc actgctacag gaaaaaatca ccacgcgact
    13861 gatcgatact gctcccacta ttccggtcgg tgtttctaat cgtcatgtgc atctgtcgca
    13921 acaggatgtt gaagcacttt ttggtgttgg ctaccaactt acgcccttta agccgttgcg
    13981 ccagcctggg caattcgccg ctgaagagtg tgtaacggtt gtcggcccga aaggttctct
    14041 gactcacgtc cgcgtacttg gaccggttcg cccgacaagc cagctggaaa tctcacgtgc
    14101 cgattgtttt actctcggca ttaaagcgcc agtgcgtgaa tccgggcaac tggaaaatgc
    14161 cggtgacgca ctgttggtgg ggccgaaagg tcatgttgag ttgcattcac aagtcatttg
    14221 cgcctggcgg catattcata tgtctcccca ggatgctcgt ctgttgaatg tcagcaatgg
    14281 gcagaaggtg agtgttcgca gtcatggtga acgccagtta acgttcgatg aagtggtggt
    14341 acgggtgcgc aatgattttg cccttgaact gcatatcgat acggaagaag ccaatgctgc
    14401 cggactgaaa aacggggcgc aggtaacact gattcgctaa gggaggccat catgaccgaa
    14461 caacagatcg acaccatcgt caacctgatc ctccagcggc tgcaacctgc ggtactggtc
    14521 atggtgacat ctgcggatgg ctatcgggat ctgattcatc agcggttggc tcgttgtggc
    14581 gaacggttgc atctggcgct ggatgaaaca atcagtgata gcgaacggtg gcagcaaatt
    14641 ggtgacgtga tacccgctaa aacatggcaa cacaaattgc cttcaacgcc ctataaagcg
    14701 ttattgctgc cgtttttgag ttacccgctg gctgtagata ttgtcaacgg tacgctgcaa
    14761 agcccggtag cgcaaagggt tcacgatgcg ctactggcgg gtattccggt actggcactg
    14821 cgttattact gcgatccgca cagcgaatta aacgcgcttc gcggtactgt tcacagcgac
    14881 tacgcggcgc atctttccgc cacgcttacc ggccttagcg agtgtggcat tacgttatgt
    14941 tccatgaatg aaatgctgga aaaactggca acagacgtca gcagtcaatc gcctgtaagt
    15001 catcatcggc gttatctgac tgtcaccgat atcgtcaata atccggcact ggcaaaatca
    15061 cccgacgccg tactgaccga tgctgcggtc gattttttga aagcacagaa aaaataacct
    15121 tacctcgata acaaacctgg agtttagata tgtcttcgaa aacaaaatgc tggctatgga
    15181 tgttactggt catcctttct gaaacctctg caacatccac acttaaaatg ttcgataaca
    15241 gtgaggggat gacaaaaacg ctgctgctgg ccctaatcgt cgtactgtat tgcatttgtt
    15301 actactcgct ttcacgggca gtaaaagata tccccgttgg tctggcttac gccacatggt
    15361 ccggtactgg cattttgatg gtttcaaccc ttgggatttt attttacggt caacacccgg
    15421 ataccgccgc cattattggt atggtcatca tagccagcgg tattatcatt atgaatctgt
    15481 tctcaaaaat gggcagtgaa gaggcggaag aaactccagt taccaacctc gataaaaaaa
    15541 tcgctaactg acaaaaggaa ttgctcatgt ttaatattgg atttttatgg ctggcacttt
    15601 ccatcggttc tgaaataacc ggtacgtcaa tgatcaaaaa aaccaatggt tttaggcgac
    15661 tgtggccttc tgttctggtg gtatgtgctt attcaacgtg ttatttcgct ctgaccagag
    15721 caatgagtac tattccggtt ggtgttgcct attcactctg gtgcggcttt gggattgttg
    15781 gcgtgacaat tttctcgatg attctttata aacaaaagcc cgatttacct gccatattct
    15841 ccatgttgct gattattagt ggcggcatta ttatgaatgt attttcaaac atgtaatgac
    15901 cccaaaagtc tgctttcacg cacaatgcgg atcagttaag gagcagttga ccggtcctta
    15961 aactgcggca ctatagcggc ttccacaaca gggagccgtt ttcttgtgca cagcccccag
    16021 ctaggctctg tctcttatac acaaatcccc acccggggat ttgtgatgtc tgtcagttga
    16081 accgccccgt gtttcctgga gagtgtttta tctgtgaact caggctgcca gctcatcatt
    16141 tccgatagaa gcataatacg ctttttctgc ttcagccgga gggatgtgcc acagcctttc
    16201 cagtaaacgt cgattgttat accagtccat ccacgtaagt gtggccagtt ccacttctgc
    16261 acgatttttc cagctcttat ggtgtattcc gctttgtaaa gatcattgat gctctccgcc
    16321 atcgcgctgc catacgagtc gcctgtacgc cctgttgatg cttgcaatcc ggcctcctta
    16381 agctgctgcg tgtagatccc tgatacatac tgagaaactt tatcactgtg atgggctgtg
    16441 ccgcacaaat gacggagcgc aatgtctgcg gcccggtaca tccgacacca atgttgtttt
    16501 cagggcaatg agcccttcca tattgtcggt atccccggta tccccggtat ccccggtatc
    16561 actgatactg acaagactga catacctgct ctcttagcca ggtaataaat gcctcaattt
    16621 ttggccactg cctgcccggt aatgtggtga tgtaataatg ctgatggcat ttcaccgtca
    16681 tatcgccaaa cggcgcgacg agctcaccac tgataagtct tttttgtacc aggcgtttcc
    16741 ttcccatcgc caccccaata tgattcatcg cggcgataac agctaaatca gaacgatcaa
    16801 agccaattcc cgaagatgtc ggcaaattaa ccgcataatg ttgcgcccaa ctatgccatt
    16861 catccgtacc ggagtcgttg ctccaggcct gtctgtcatg gagcaacgta cagtggcgaa
    16921 ggttaattac ctggttggtt aaagcatgtc tttgagcgta ttccgggcta catacaggca
    16981 ggatttcttc atccatcaga aagtgatgag tcagttgcgc tgacggcgcg tcatcaaagt
    17041 agattgccaa atcgattccg gcacgttgca aattgacatt gtcattaccg gtgagcacgg
    17101 tgagcgaaat agacggatag cggcgtgtaa agtcacctaa tgcgggcacc aaccagcatt
    17161 gggcgataga gggccgggaa tacagcgtta acgttcccga taattcctga tttttgatat
    17221 caagaatttc ctggttcagg gtatccagcg acgattttag cgcccaataa acgcgtttcc
    17281 cctcgtgcgt taattccact ttgcgatggg aacgaacaaa caactgaata cctaattctt
    17341 cttccagctg attgatacgg tgacttaccg cactggggct cagcgacaat tcctctgccg
    17401 cgagagcgaa ggactgatgc ctggcagcca cttcaaaagt atgcagtttt gatagttgcc
    17461 agccgttaag cagtcgattt cttatttcac gaaggggttc cataatcacc tcatttttct
    17521 cttaagtgta aaaaaatagc ggcaaaattt cagctgtaag gtgagctaaa gtgaaccata
    17581 tctcaattca ccttcatttt tagatgtaaa tcactccctt gatgcaattt agctcatgtg
    17641 aaaggcaaat tttatcgttt gtcagcctgc gttgtttttt tgtccaatat catcaggtta
    17701 atcacagggg aaggtgagat atgcactctc aaatctgggt tgtgagcacg ctgcttatca
    17761 gcatcgtgtt aattgtactg accatcgtga agttcaaatt ccacccgttt ctggcgctgt
    17821 tgctggccag cttcttcgt
//
LOCUS       DAFGPF010000101        17688 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFGPF010000101 DAFGPF010000000
VERSION     DAFGPF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17688
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.101"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            52..1479
                     /gene="rmuC"
                     /locus_tag="LSX49_003821"
     CDS             52..1479
                     /gene="rmuC"
                     /locus_tag="LSX49_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HBL7170177.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYQTQVSIETDTRSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAI
                     GQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            1574..2329
                     /gene="ubiE"
                     /locus_tag="LSX49_003822"
     CDS             1574..2329
                     /gene="ubiE"
                     /locus_tag="LSX49_003822"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HBL7170178.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKTMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            2343..2948
                     /gene="ubiJ"
                     /locus_tag="LSX49_003823"
     CDS             2343..2948
                     /gene="ubiJ"
                     /locus_tag="LSX49_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HBL7170179.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLAALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKALRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            2945..4585
                     /gene="ubiB"
                     /locus_tag="LSX49_003824"
     CDS             2945..4585
                     /gene="ubiB"
                     /locus_tag="LSX49_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HBL7170180.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKPLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVATLEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            4664..4933
                     /gene="tatA"
                     /locus_tag="LSX49_003825"
     CDS             4664..4933
                     /gene="tatA"
                     /locus_tag="LSX49_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HBL7170181.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            4937..5452
                     /gene="tatB"
                     /locus_tag="LSX49_003826"
     CDS             4937..5452
                     /gene="tatB"
                     /locus_tag="LSX49_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HBL7170182.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNETVHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            5455..6231
                     /gene="tatC"
                     /locus_tag="LSX49_003827"
     CDS             5455..6231
                     /gene="tatC"
                     /locus_tag="LSX49_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HBL7170183.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIISVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            6273..7055
                     /gene="tatD"
                     /locus_tag="LSX49_003828"
     CDS             6273..7055
                     /gene="tatD"
                     /locus_tag="LSX49_003828"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HBL7170184.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAVTEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAAELNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVACGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNAPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(7052..7540)
                     /gene="rfaH"
                     /locus_tag="LSX49_003829"
     CDS             complement(7052..7540)
                     /gene="rfaH"
                     /locus_tag="LSX49_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HBL7170185.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPSTPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            7707..9200
                     /gene="ubiD"
                     /locus_tag="LSX49_003830"
     CDS             7707..9200
                     /gene="ubiD"
                     /locus_tag="LSX49_003830"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HBL7170186.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            9246..9947
                     /gene="fre"
                     /locus_tag="LSX49_003831"
     CDS             9246..9947
                     /gene="fre"
                     /locus_tag="LSX49_003831"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HBL7170187.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
     gene            complement(10128..11291)
                     /gene="fadA"
                     /locus_tag="LSX49_003832"
     CDS             complement(10128..11291)
                     /gene="fadA"
                     /locus_tag="LSX49_003832"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HBL7170188.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMEHKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(11301..13490)
                     /gene="fadB"
                     /locus_tag="LSX49_003833"
     CDS             complement(11301..13490)
                     /gene="fadB"
                     /locus_tag="LSX49_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HBL7170189.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLIEGAMAILRQAINGDLDWKAKRQPK
                     LEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     DYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDVVVDDLLAKVSQPKRDFSE
                     EEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            13680..15011
                     /gene="pepQ"
                     /locus_tag="LSX49_003834"
     CDS             13680..15011
                     /gene="pepQ"
                     /locus_tag="LSX49_003834"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HBL7170190.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA"
     gene            15011..15625
                     /locus_tag="LSX49_003835"
     CDS             15011..15625
                     /locus_tag="LSX49_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HBL7170191.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITLLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYSQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            15664..17115
                     /gene="trkH"
                     /locus_tag="LSX49_003836"
     CDS             15664..17115
                     /gene="trkH"
                     /locus_tag="LSX49_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HBL7170192.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFSLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            17127..17672
                     /gene="hemG"
                     /locus_tag="LSX49_003837"
     CDS             17127..17672
                     /gene="hemG"
                     /locus_tag="LSX49_003837"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HBL7170193.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTN
                     SYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
BASE COUNT         4092 a         4479 c         4870 g         4247 t
ORIGIN      
        1 gtacagcaca attctatttt gtgcgggtaa gttgttgcgt caggaggcgt tgtggatttc
       61 tcaatcatgg tttacgcagt cattgcgttg gtgggtgtgg caattggctg gctgtttgcc
      121 agttatcaac atgcgcagca aaaagccgag caattagctg aacgtgaaga gatggtcgcg
      181 gagttaagcg cggcaaaaca acaaattacc caaagcgagc actggcgcgc agagtgtgaa
      241 ttgctcaata acgaagtgcg cagcctgcaa agtattaaca cctcgctgga ggccgatctg
      301 cgtgaagtga ccacgcggat ggaagccgca cagcaacacg ctgacgataa aattcgccag
      361 atgatcaaca gcgaacagcg cctcagtgag caatttgaaa accttgccaa ccgtattttt
      421 gaacacagta atcgtcgggt tgatgagcaa aatcgccaga gtctgaacag tcttttgtcg
      481 ccgttgcgtg aacaactgga cggttttcgc cgtcaggttc aggacagttt cggtaaagaa
      541 gcacaagaac gtcataccct gactcacgaa atccgcaatc tccagcaact caacgcgcaa
      601 atggcccagg aagcgatcaa cctgacgcgt gcgctgaaag gcgacaataa aacccagggc
      661 aactggggcg aagtggtgct aacccgcgta ctggaggcgt ctggtctgcg tgaagggtat
      721 gaatatcaga ctcaagtgag tatcgaaacc gacactcgtt cgcgaatgca accggatgtc
      781 atcgtgcggc tgccgcaggg caaagatgtg gtgatcgacg ccaaaatgac gctggttgcc
      841 tatgaacgtt atttcaacgc tgaagatgac tacacacgtg aaagcgcgct acaggaacat
      901 atcgcgtcgg tgcgtaacca tatccgtttg ctgggacgca aagattatca acagctgccg
      961 gggctgcgaa ctctggatta cgtgctgatg tttattcccg ttgaacccgc ttttttactg
     1021 gcgcttgacc gtcagccgga gctgatcacc gaagcgttga aaaacaatat catgctggtt
     1081 agcccgacta cgctgctggt ggcgctgcgc actatcgcca acctgtggcg ttatgagcat
     1141 caaagccgca acgcccagca aatcgccgat cgtgccagca agctgtacga caagatgcgt
     1201 ttgttcatcg atgacatgtc cgcgattggt caaagtctcg acaaagcgca ggataactat
     1261 cgccaggcaa tgaaaaaact ctcttcaggt cgcggaaatg tgctggcgca ggcagaagcg
     1321 tttcgcggtt taggggtaga aattaaacgc gagattaatc cggatttggc tgaacaggcg
     1381 gtgagccagg atgaagagta tcgacttcgg tcggttccgg agcagccgaa tgatgaagct
     1441 tatcaacgcg atgatgaata taatcagcag tcgcgctagc ccattggggg tagttaagcc
     1501 gggtagaaat ctagggcatc gacgcccaat ctgttacact tctggaacaa ttttttgatg
     1561 agcaggcatt gagatggtgg ataagtcaca agaaacgacg cactttggtt ttcagaccgt
     1621 cgcgaaggaa caaaaagcgg atatggtcgc ccacgttttc cattccgtgg catcaaaata
     1681 cgatgtcatg aatgatttga tgtcattcgg tattcatcgt ttgtggaagc gattcacgat
     1741 tgattgcagc ggcgtacgcc gtgggcagac cgtgctggat ctggctggtg gcaccggcga
     1801 cctgacagcg aaattctctc gcctggtcgg agaaactggc aaagtggtcc ttgctgatat
     1861 caatgaatcc atgctcaaaa tgggccgcga gaagctgcgt aatatcggtg tgattggcaa
     1921 cgttgagtat gttcaggcga acgctgaggc gctgccgttc ccggataaca cctttgattg
     1981 catcaccatt tcgtttggtc tgcgtaacgt caccgacaaa gataaagcac tgcgttcaat
     2041 gtatcgcgtg ctgaaacccg gcggccgcct gctggtgctt gagttctcga agccaattat
     2101 cgagccgctg agcaaagcct atgatgcata ctccttccat gtgctgccgc gtattggctc
     2161 actggtcgcg aacgacgccg acagctaccg ttatctggca gaatccatcc gtatgcatcc
     2221 cgatcaggat accctgaaaa ccatgatgca ggatgccgga ttcgaaagtg ttgactacta
     2281 caatctgacg gcaggggttg tggcgctgca tcgtggttat aagttctgac aggagaccgg
     2341 aaatgccttt taaaccttta gtgacggcag gaattgaaag tctgctcaac accttcctgt
     2401 atcgctcacc cgcgctgaaa acggcccgct cgcgtctgtt gggcaaagtg ctgcgcgtgg
     2461 aggtaaaagg cttttcgacg tcattgattc tggtgttcag cgaacgccag gtcgatgtac
     2521 tgggcgaatg ggcaggcgat gctgactgca ccgttatcgc ttacgccagc gtgttgccga
     2581 aacttcgcga tcgccagcag cttgccgcac tgattcgtag tggtgagctg gaagtgcagg
     2641 gcgatattca ggtggtgcaa aacttcgttg cgctggcaga tctggctgag ttcgaccctg
     2701 cggaactgct ggccccttat accggtgata tcgccgctga aggtatcagc aaagccctgc
     2761 gcgggggcgc aaagttcctg catcacggca ttaagcgcca gcaacgttat gtggcggaag
     2821 ccattactga agagtggcgt atggcacccg gtccgcttga agtggcctgg tttgcggaag
     2881 agacggctgc cgtcgagcgt gctgttgatg ccctgaccaa acggctggaa aaactggagg
     2941 ctaaatgacg ccaggtgaag tacggcgcct atatttcatc attcgcactt ttttaagcta
     3001 cggacttgat gaactgatcc ccaaaatgcg tatcaccctg ccgctacggc tatggcgata
     3061 ctcattattc tggatgccaa atcggcataa agacaaacct ttaggtgagc gactacgact
     3121 ggccctgcaa gaactgggac cagtatggat caagttcggg cagatgttat caacccgccg
     3181 cgatcttttt ccgccgcata ttgccgatca gctggcgtta ttgcaggaca aagtcgctcc
     3241 gtttgatggc aagctggcga agcagcagat tgaagctgca atgggcggct tgccggtaga
     3301 agcgtggttt gacgattttg aaatcaagcc gctggcttct gcttctatcg cccaggttca
     3361 taccgcgcga ttgaaatcga atggtaaaga ggtggtgatt aaagttatcc gcccggatat
     3421 tttgccggtc attaaagcgg atctgaaact tatctaccgt ctggctcgct gggtgccgcg
     3481 tttgctgccg gatggtcgcc gtctgcgccc aaccgaagtg gtgcgcgagt acgaaaagac
     3541 cttgattgat gaactgaatt tgctgcggga atctgccaac gccattcagc ttcgacgcaa
     3601 ttttgaagac agcccgatgc tctacatccc ggaagtttac cctgactatt gtagtgaagg
     3661 gatgatggtg atggagcgta tttacggcat tccggtgtct gatgttgcga cgctggagaa
     3721 aaacggcacc aacatgaaat tgctggcgga acgcggcgtg caggtgttct tcactcaggt
     3781 ctttcgcgac agctttttcc atgctgatat gcaccctggc aacatcttcg taagctatga
     3841 acacccggaa aacccgaaat atatcggcat tgattgcggg attgttggct cgctaaacaa
     3901 agaagataaa cgctatctgg cggaaaactt tatcgccttc tttaatcgcg actatcgcaa
     3961 agtggcagag ctacacgtcg attctggttg ggtgccacca gataccaacg ttgaagagtt
     4021 cgaatttgcc attcgtacgg tctgtgaacc tatctttgag aaaccgctgg ccgaaatttc
     4081 gtttggacat gtactgttaa atctgtttaa tacggcgcgt cgcttcaata tggaagtgca
     4141 gccgcaactg gtgttactcc agaaaaccct gctctacgtc gaaggggtag gacgccagct
     4201 ttatccgcaa ctcgatttat ggaaaacggc gaagcctttc ctggagtcgt ggattaaaga
     4261 tcaggtcggt attcctgcgc tggtgagagc atttaaagaa aaagcgccgt tctgggtcga
     4321 aaaaatgcca gaactgcctg aactggttta cgacagtttg cgccagggca agtatttaca
     4381 gcatagtgtt gataagattg cccgcgagct tcagtcaaat catgtacgtc agggacaatc
     4441 gcgttatttt ctcggaattg gcgctacgtt agtattaagt ggcacattct tgttggtcag
     4501 ccgacctgaa tgggggctga tgcccggctg gttaatggca ggtggtctga tcgcctggtt
     4561 tgtcggttgg cgcaaaacac gctgattttt tcatcgctca aggcgggccg tgtaacgtat
     4621 aatgcggctt tgtttaatca tcatctacca cagaggaaca tgtatgggtg gtatcagtat
     4681 ttggcagtta ttgattattg ccgtcatcgt tgtactgctt tttggcacca aaaagctcgg
     4741 ctccatcggt tccgatcttg gtgcgtcgat caaaggcttt aaaaaagcaa tgagcgatga
     4801 tgaaccaaag caggataaaa ccagccagga tgctgatttt actgcgaaaa ctatcgccga
     4861 taagcaggcg gatacgaatc aggaacaggc taaaacagaa gacgcgaagc gccacgataa
     4921 agagcaggtg taatctgtgt ttgatatcgg ttttagcgaa ctgctattgg tgttcatcat
     4981 cggcctcgtc gttctggggc cgcaacgact gcctgtggcg gtaaaaacgg tagcgggctg
     5041 gattcgtgcg ttgcgttcac tggcgacaac ggtgcagaac gaactgaccc aggagttaaa
     5101 actccaggag tttcaggaca gtctgaaaaa ggttgaaaag gcgagcctca ctaacctgac
     5161 gcccgaactg aaagcgtcga tggatgaatt acgccaggct gcggagtcga tgaagcgttc
     5221 ctacgttgca aacgatcctg aaaaggcgag cgatgaagcg cacaccatcc ataacccggt
     5281 ggtgaaagac aatgaaactg tgcatgaagg cgtaacgcct gctgctgcac aaacgcaggc
     5341 cagttcgccg gaacagaagc cagaaaccac gccagagccg gtggtaaaac ctgctgcgga
     5401 cgctgaaccg aaaaccgctg caccttcccc ttcgtcgagt gataaaccgt aaacatgtct
     5461 gtagaagata ctcaaccgct tatcacgcat ctgattgagc tgcgtaagcg tctgctgaac
     5521 tgcattatct cggtgatcgt gatattcctg tgtctggtct atttcgccaa tgacatctat
     5581 cacctggtat ccgcgccatt gatcaagcag ttgccgcaag gttcaacgat gatcgccacc
     5641 gacgtggcct cgccgttctt tacgccgatc aagctgacct ttatggtgtc gctgattctg
     5701 tcagcgccgg tgattctcta tcaggtgtgg gcgtttatcg ccccagcgct gtataagcat
     5761 gaacgtcgcc tggtggtgcc gctgctggtt tccagctctc tgctgtttta tatcggcatg
     5821 gcgttcgcct actttgtggt ctttccgctg gcatttggct tccttgccaa taccgcgccg
     5881 gaaggggtac aggtatccac cgacatcgcg agctatttaa gcttcgttat ggcgctgttt
     5941 atggcgtttg gtgtctcctt tgaagtgccg gtggcaattg tgctgctgtg ctggatgggg
     6001 attacctcgc cagaagactt acgcaaaaaa cgcccgtatg tgctggttgg tgcattcgtt
     6061 gtcgggatgt tgctgacgcc gccggatgtc ttctcgcaaa cgctgttggc gatcccgatg
     6121 tactgcctgt ttgaaatcgg tgtcttcttc tcacgctttt acgttggtaa agggcgaaac
     6181 cgggaagagg aaaacgacgc tgaagcagaa agcgaaaaaa ctgaagaata aattcaaccg
     6241 cccgtcaggg cggttgtcat atggagtaca ggatgtttga tatcggcgtt aatttgacca
     6301 gttcgcaatt tgcgaaagac cgtgatgatg ttgtagcgcg cgcttttgac gcgggagtta
     6361 atgggctact catcaccggt accaatctgc gtgaaagcca gcaggcgcaa aagctggcgc
     6421 gtcagtattc gtcctgttgg tcaacggcgg gcgtacatcc tcacgacagc agccagtggc
     6481 aagctgtgac tgaagaagcg attattgagc tggccgcgca gccagaagtg gtggcgattg
     6541 gtgaatgtgg tctcgacttt aaccgcaact tttcgacgcc ggaagagcag gaacgcgctt
     6601 ttgttgccca gctacgcatt gccgcagaat taaacatgcc ggtatttatg cactgtcgcg
     6661 atgcccacga gcggtttatg acattgctgg agccgtggct ggataaactg cctggtgcgg
     6721 ttcttcattg ctttaccggc acacgcgaag agatgcaggc gtgcgtggcg tgtggaattt
     6781 atatcggcat taccggttgg gtttgcgatg aacgacgcgg gctggagctg cgggaattgt
     6841 tgccgttgat tccggcggag aaattgctga tcgaaactga tgcgccgtat ctgctccctc
     6901 gcgatctcac gccaaagcca tcatcccggc gcaacgcgcc agcccatctg ccccatattt
     6961 tgcaacgtat tgcgcactgg cgtggagaag atgccgcatg gctggctgcc accacggatg
     7021 ccaatgtcaa aacactgttt gggattgcgt tttagagttt gcggaactcg gtgttcttta
     7081 cgctgtgctt aatttcttta ttgataagat taagcaatag catggagcga gcctctccgt
     7141 ctggctcggt gaaaatggcc tgaaaacctt cgaatgcgcc ttcagtaata atcactttat
     7201 caccaggata cggcgtcgat ggatcgacaa tatctttcgg tttatacact gataactgat
     7261 gaatcaccgc cgatgggact atcgctggcg acgcgccaaa gcgcacgaag tggctgacac
     7321 cgcgggtcgc gttgatagtc gtggtatgaa tcacttccgg atcgaactcc acaaacaagt
     7381 agttggggaa caatggctca ctgactgcag tacgtttgcc acgcacgatt ttttccaggg
     7441 tgatcatcgg tgccaggcaa ttcacagcct gtctttcgag gtgttcctgg gcacgttgaa
     7501 gttgcccgcg cttgcagtac agtaaatacc aggattgcat aatgactctt atccgtttaa
     7561 tcggggcgca aggatagcaa aagctttacg ctaagttaat tatattcccc ggtttgcgtt
     7621 ataccgtcag agttcacgct aatttaacaa atttacagca tcgcaaagat gaacgccgta
     7681 taatgggcgc agattaagag gctacaatgg acgccatgaa atataacgat ttacgcgact
     7741 tcttgacgct gcttgaacag cagggtgagc taaaacgtat cacgctcccg gtggatccgc
     7801 acctggaaat cactgaaatt gctgaccgca ctttgcgtgc cggtgggcct gcgctgttgt
     7861 tcgaaaaccc taaaggctac tcaatgccgg tgctgtgcaa cctgttcggt acgccaaagc
     7921 gcgtggcgat gggcatgggg caggaagatg tttcggcgct gcgtgaagtt ggtaaattat
     7981 tggcgtttct gaaagagccg gagccgccaa aaggtttccg cgacctgttt gataaactgc
     8041 cgcagtttaa gcaagtattg aacatgccga caaagcgact gcgtggtgca ccctgccaac
     8101 aaaaaatcgt ctctggcgat gacgtcgatc tcaatcgcat tcccattatg acctgctggc
     8161 cggaagatgc cgcgccgctg attacctggg ggctcaccgt aacgcgtggc ccgcataaag
     8221 agcggcagaa tctgggcatt tatcgccagc agctaattgg taaaaacaaa ctgattatgc
     8281 gctggctgtc gcatcgcggc ggcgcgttgg attatcagga gtggtgtgcg gcgcatccgg
     8341 gcgaacgttt cccggtttct gtggcgctgg gtgccgatcc tgccacgatt ctcggtgcag
     8401 tcacccccgt tccggatacg ctttcagagt atgcgtttgc cggattgctg cgcggtacca
     8461 agaccgaagt ggtgaagtgt atctccaatg accttgaagt gcccgccagt gcggagattg
     8521 tgctggaagg gtatatcgaa caaggcgaaa ctgcgccgga agggccgtat ggcgaccata
     8581 ccggttacta taacgaagtc gatagttttc cggtatttac cgtgacgcat attacccagc
     8641 gtgaagatgc gatttatcat tccacctata ccgggcgtcc gccagatgaa cctgcggtac
     8701 tgggtgtagc actgaacgaa gtgttcgtgc cgattctgca aaaacagttc ccggaaattg
     8761 tcgattttta tctgccgccg gaaggctgtt cttatcgtct ggcggtagtg acgatcaaaa
     8821 aacagtacgc cggacacgcg aagcgcgtca tgatgggcgt ctggtcgttc ttacgccagt
     8881 ttatgtacac taaatttgtg atcgtttgcg atgatgacgt caacgcccgc gactggaacg
     8941 atgtgatttg ggcgattacc acccgtatgg acccggcgcg ggatactgtt ctggtagaaa
     9001 atacgcctat tgattatctg gattttgcct cgcctgtctc cgggctgggt tcaaaaatgg
     9061 ggctggatgc cacgaataaa tggccgggtg aaacccagcg tgaatgggga cgtcccatca
     9121 aaaaagatcc agatgttgtc gcgcatattg acgccatttg ggatgaactg gctattttta
     9181 acaacggtaa aagcgcctga tgcgcgtttg ttttgcccta tttatcgatc cgacagagaa
     9241 agcgcatgac aaccttaagc tgtaaagtga cctcggtaga agctatcacg gataccgtat
     9301 atcgtgtccg catcgtgcca gacgcggcct tttcttttcg tgctggtcag tatttgatgg
     9361 tagtgatgga tgagcgcgac aaacgtccgt tctcaatggc ttcgacgcca gatgaaaaag
     9421 ggtttatcga gctgcatatt ggcgcttctg aaatcaacct ttacgcgaaa gcagtcatgg
     9481 accgcatcct caaagatcat caaatcgtgg tcgatattcc ccacggagaa gcgtggctgc
     9541 gcgatgatga agagcgtccg atgattttga ttgcgggcgg caccgggttc tcttatgccc
     9601 gctcgatttt gctgacagcg ttggcgcgta acccaaaccg tgatatcacc atttactggg
     9661 gcgggcgtga agagcagcat ctgtatgatc tctgcgagct tgaggcgctt tcgttgaagc
     9721 atcctggtct acaagtggtg ccggtggttg aacaaccgga agcgggctgg cgtgggcgta
     9781 ctggcaccgt gttaacggcg gtattgcagg atcatggtac gctggcagag catgatatct
     9841 atattgccgg acgttttgag atggcgaaaa ttgcccgtga cctgttttgc agcgagcgta
     9901 atgcgcggga agatcgcctg tttggcgatg cgtttgcatt tatctgagat ataaaaaacc
     9961 cgcccctgac aggcgggaag aacggcaact aaaactttat acagtggcat tactctacgt
    10021 tgcatccggc aaacagtgcc cgatgcaacg ctgccgcgtc ttatcgggcc tacaaaagtt
    10081 ctgaaccgtg ggccggataa ggcgttcacg ccgcatccgg caagtggtta aacccgctca
    10141 aacaccgttg caatgccctg acccagaccg atacacatcg tcgccagacc aaactggacg
    10201 tctttgtgtt ccatcagatt cagcagcgtg gtgctgatac gcgcaccgga acaacccagc
    10261 ggatgaccca gcgcgatcgc gccaccgttg aggttgatct tctcgtcaat ctgctccatt
    10321 agcccgagat ctttaataca cggcaggatc tgcgcggcaa aggcttcgtt catctcgaat
    10381 acgccgatat cgctggcaga aagccccgct tttttcagcg ccagcttcga ggccggaacc
    10441 ggaccataac ccataataga tgggtcacaa cccacaaccg ccatcgaacg cacgcgggcg
    10501 cgcggcttaa gacctaattc acgggcgcgg ctttcactca tcaccagcat ggcagctgcg
    10561 ccatcggaaa gcgcagaaga tgtacccgcc gttaccgtac cgctgacggg atcaaacgcc
    10621 ggacgcagtg tggcgagggc ttccacggtg gtttccgggc gaatcacttc gtcgtaatta
    10681 aactgcttca atacgccgtc ggcatcgtga ccaccggtcg ggatgatttc atttttaaat
    10741 gcgcctgact gcgtggcggc ccacgcgcgg gcgtgtgacc gcgcggcaaa ggcatcctgc
    10801 atttcacggc tgataccgtg catacgcgcc agcatttctg ccgttaagcc catcatgccc
    10861 gccgctttgg cgacattacg gctcaggccg gggtgaaaat cgacgccgtg actcattggc
    10921 acatggccca tatgctccac gccgccaacc agacatgcct gcgcatcacc ggtcatgatc
    10981 attcgtgctg cgtcatgcag tgcctgcatg gatgaaccac acaagcgatt aacggtaacc
    11041 gccgggacag agtgcggcac ttcagccaac agtgccgcgt tacgggcgat attaaaaccc
    11101 tgctccagtg tttgctgcac acaaccccag taaatatcgt caagggccgc cgcttccagt
    11161 gccgggttac gcgccagcag gctacgcatt aaatgagcgg agagatcttc cgcacgcacg
    11221 ttacgaaaag caccgccctt cgaacggccc atcggggtgc gaattgcatc gacaatgaca
    11281 acctgttcca ttgtgactcc ttaagccgtt ttcaggtcgc caaccggacg ggctggctca
    11341 accgggggat agtacggttc gttatgacgt gctttattac gcagaccttc cggtacttca
    11401 tacagcgggc cgaggtgctg atattgctgt gccatatcga ggtattttgc gctgccgagg
    11461 gtgtccagcc agcggaacgc gccgccgtgg aacggaggga agcccaggcc gtagaccagc
    11521 gccatatccg cttctgccgg agtggcgata atgccctctt ccagacagcg gaccacttcg
    11581 ttgaccatcg ggatcatcat gcgggcgata atctcttctt cgctgaaatc gcgcttcggc
    11641 tggctcactt ttgccagcag gtcgtcaacg acgacatctt cttctttctt cggcttacct
    11701 ttgctgtctt ctttataacg ccagaaaccg aggccgttct tctgaccaaa gcggttggca
    11761 tcaaacagcg cgtcgatggc atcgcgataa tctttctgca tccgctgcgg gaagcctgct
    11821 gccatgacag cctgggcgtg atgcgcggtg tcaatgccca caacatccag cagatatgcc
    11881 ggacccatcg gccagccaaa ctgtttttcc atcactttgt cgatcttgcg gaaatccgcg
    11941 ccgtcgcgca gcaactggct gaaaccggcg aaatagggga acagtacacg gttgacgaag
    12001 aagccggggc agtcgttaac cacaatcggc gttttgccca tcttgctcgc ccaggcgacg
    12061 actttcgcga tggtttcgtc ggagcttttc tcgccgcgaa taatttctac caacggcatt
    12121 cggtggaccg ggttaaagaa gtgcatcccg cagaagtttt ccggacgttc cagcgcgttg
    12181 gccagttcgc tgataggaat ggttgaagtg ttcgacgcca gtacggtatc cgggcgtact
    12241 ttctgctcgg tttctgccag cacggctttt ttcactttcg ggttttcaac aaccgcttct
    12301 accacaacat ccacgcggtc aaacccggcg tagtcgagcg ttgggtgaat tgtggagatc
    12361 acgccagcca gtttcagacc atcgatcttg ccgcgctcaa gctgcttgtt cagcagtttc
    12421 gcggcttcgg tcatgccgag ggttaacgac ttgtcgttga tatctttcat gacaaccggc
    12481 acgcctttcc acgcagactg gtaagcgatg ccgccgccca taatgcctgc gcccagcaca
    12541 gcggcctgtt tcggggtttc aacatctttg gtgagtttct tcgctttacc ttttacatat
    12601 tgatcgttaa ggaaaatgcc gaccagtgcg cgggcttcgt tggtatgcgc cagcgggaca
    12661 aaacttttgt tttccaggtt taaggcttct tcacgaccaa aacgggccgc agcttcaatg
    12721 gtttttactg cggtgatggg ggccggataa tgtttccccg ccgtttgtgc gaccatccct
    12781 ttagcgatgg tgaagctcat ggtggcttca atcttgctca gttttagcgg ttccagcttc
    12841 ggctgacgtt tcgctttcca gtcgaggtcg ccgttaatgg cctggcgtaa aatcgccatc
    12901 gccccttcaa tcagtttttc tgctttgact acaccatcca ccagaccgat tttcagcgcc
    12961 tgatccgcgc cgacatcttt accggcggca atgatttcca gcgcactgtc agcgcccagc
    13021 atacgtggca tacgtacaga accgccaaag cccggcatga tgcccagttt ggtttccggc
    13081 agaccgatgc gcagatccgg cgtcgccaga cgataatcgg tcgccagcac gcattcgcag
    13141 ccaccgccca gcgcatagcc gttgacggca gcaatggtcg gcaccgggag atcttccagg
    13201 cgattaaaca cgctattggc aaagtgcagc cactgactta actgttcttc aggaacgagg
    13261 aacagggaca aaaattcggt gatatcagca ccgacgataa aggctgcttt gttcgaacgc
    13321 agcagcagcc cttttagatc tgattgctgt tccagcacgc cgatggcctc gccgaggctg
    13381 gcgacggtcg cagtgtcgag tttattaact gaacctgggg catcaaatac cagttcggca
    13441 atgccatctt ccagccagtc aaggtacagg gtgtcgcctt tgtaaagcat gtcagtctcc
    13501 tgaatccgca aggtgatctg gtcgtaccag atgcatcgaa gtgtgtattt tgtgttaaaa
    13561 atatgcaaat aaaagattaa agaaatgccg atctgatcac gctcggcaga aatcacgctc
    13621 tggatgaacg atgtgctaag atgcggagac ttaaggtcaa aaaaacagaa gggtaaaaaa
    13681 tggaatcact ggcctcactc tataaaaatc atatcgctac cttacaagaa cggactcgcg
    13741 atgcgctggc gcgcttcaag ctggatgcgt tacttattca ctccggcgaa ctgttcaacg
    13801 tttttctcga cgatcatccc tatccgttta aagtgaaccc gcaattcaaa gcgtgggtgc
    13861 cggtaactca ggtgccaaac tgctggctgc tggtggatgg cgtgaacaag ccgaaactgt
    13921 ggttttatct gccggttgat tactggcaca acgtcgaacc gctaccgacc tccttctgga
    13981 ctgaagatgt agaagtgatc gcgctgccga aagccgatgg cattggtagc ctgctgcctg
    14041 ctgcgcgcgg caatatcggt tatatcggtc cggtgccgga acgtgcgctg caactgggta
    14101 ttgaggccag caacatcaac ccgaaagggg tgatcgacta cctgcattac taccgctcct
    14161 tcaaaaccga gtacgaactg gcctgtatgc gtgaagcgca gaaaatggcg gtcaatggtc
    14221 atcgtgcggc agaagaagcg ttccgttctg gcatgagcga gttcgatatc aacattgcct
    14281 atctgaccgc gaccggtcat cgtgataccg acgtacctta tagcaacatt gtggcgctta
    14341 acgaacacgc tgcggtgttg cattacacca aactggacca ccaggcaccg gaagagatgc
    14401 gcagcttcct gctggatgcc ggggccgaat ataacggcta tgcggctgat ctgacccgta
    14461 cctggtcggc aaaaagcgac aacgactacg cacagctggt gaaagacgta aatgatgagc
    14521 aactggcgct gatcgccacc atgaaagcag gcgtcagcta tgtggattac catatccagt
    14581 tccatcagcg catcgccaaa ctgctgcgta aacatcaaat catcaccgat atgagtgaag
    14641 aagcgatggt cgaaaacgat ctcaccggac cgtttatgcc gcacggtatc ggccatccgc
    14701 tgggcctgca ggtgcatgac gtagccggtt ttatgcagga tgatagcggt acgcacctcg
    14761 cggcaccggc aaaatatccg tacctgcgct gcacccgtat tctccagccg ggcatggtgt
    14821 taaccatcga accgggtatc tacttcatcg aatcgctgct ggcaccgtgg cgtgaagggc
    14881 agttcagcaa acacttcaac tggcagaaaa ttgaagcact gaaaccgttc ggcggcattc
    14941 gtatcgaaga caacgtggtg attcacgaaa acaacgtgga aaacatgacc cgggatctga
    15001 aactggcgtg atggaaagct ggttaattcc tgcggcaccg gtcacggtcg ttgaagagat
    15061 caaaaagagc cgcttcatta cgctgttggc gcataccgat ggcgttgagg cggcaaaagc
    15121 gtttgttgaa tcggtgcggg cagaacaccc cgatgcccgc caccattgcg tggcgtgggt
    15181 ggcgggtgcg ccggatgatt ctcaacagct gggtttctct gacgacgggg agccggcggg
    15241 aacggcaggt aaaccgatgc tcgcccaact aatgggcagc ggcgtcgggg aaattaccgc
    15301 tgtggtggtg cgctactacg gcggcatatt gcttggcacc ggtgggttag tgaaagcgta
    15361 tggcggcggc gtgaatcagg cgctgcgcca gctaacgacc caacgcaaga caccgttaac
    15421 cgaatatact ttgcaatgtg aatatagtca gttaaccggc attgaagcgt tgctggggca
    15481 gtgtgacggc aaaattatca acagtgatta tcaggcattc gttctgctgc gggtggcgct
    15541 tccggcggcg aaagtggctg aattttccgc aaagctggcg gattttagcc gtggttcatt
    15601 gcaattgtta gcgattgaag aataatcccc acttcgtttt gcagaactaa ggaagcggca
    15661 gagatgcatt ttcgcgccat tacccgaatc gttggactac tggttatctt attttcaggg
    15721 accatgatta tccctgggct ggtagcactc atctaccggg atggagcggg ccgcgctttt
    15781 acccagacct tttttgtcgc cctcgccatt ggctctatgc tttggtggcc gaaccgcaaa
    15841 gagaagggtg aactgaaatc ccgtgagggg tttctgatag tggtgctgtt ctggaccgtg
    15901 ctgggtagcg tcggtgcgct cccttttatc ttctcggaaa gcccgaacct cacgattacc
    15961 gatgcgtttt ttgaatcttt ctctggcctg accaccacgg gggccactac gctggtgggg
    16021 ctggattcgc tccctcacgc catcctcttt tatcgccaga tgctgcaatg gtttggcggg
    16081 atggggatca tcgtgttggc ggttgcgata ctgcctatcc tcggcgtggg tgggatgcag
    16141 ctctatcgcg cagaaatgcc cggcccgctg aaagataaca aaatgcgccc gcgaattgcg
    16201 gaaacggcga aaaccctgtg gttgatttat gtcttgctga ccgtcgcctg tgcgctggcg
    16261 ttgtggtttg ctggaatgga tgcctttgat gccatcggcc atagctttgc gactatcgct
    16321 attggcggct tctcgacaca tgatgccagt atcggttatt tcgacagccc gactattaac
    16381 actatcattg ctatcttcct gctgatctct ggctgtaact acggtctgca cttttcactg
    16441 ttaagtgggc gtagtctgaa ggtttattgg cgcgatccgg aatttcgcat gtttatcggc
    16501 gtacagtttt cactggtggt tatttgtaca ctcgtactgt ggtttcataa tgtctacagt
    16561 tcggcgctga tgacaattaa ccaggcgttt ttccaggtgg tgtcgatggc gacaaccgcc
    16621 gggtttacaa ctgacagcat tgcccgctgg ccgctctttt tgccggtact gcttttatgt
    16681 tcagctttta tcggcggttg cgccgggtca acgggcggtg gcctgaaagt gatccgcatc
    16741 ctgttgctgt ttaagcaggg gaaccgtgag ctgaaacgac tggtgcatcc gaacgccgtc
    16801 tatagcatta agctggggaa tcgcgcactg ccggaacgta tcctcgaagc cgtttgggga
    16861 tttttctccg cctatgcatt ggtgtttatt gtcagtatgc tggcgattat cgccacgggc
    16921 gtggatgact tttctgcctt tgcctcggtt gttgcaacat tgaataacct ggggccaggg
    16981 cttggcgtgg ttgctgataa ctttaccagt atgaacccgg tggctaaatg gatcctgatt
    17041 gccaacatgc tgtttggtcg tctcgaggtc tttacattgc tggtgctctt taccccgact
    17101 ttctggcgtg aatgatggag taatacgtga aaacattaat tcttttctca acaagggacg
    17161 gacaaacgcg cgagattgcc tcctacctgg cttcggaact gaaagaactg gggatccagg
    17221 cggatgtcgc caatgtgcac cgcattgaag aaccacaatg ggaaaactat gaccgtgtgg
    17281 ttattggtgc ttctattcgc tatggtcact accactctgc gttccaggaa tttgtcaaaa
    17341 agcatgcgac gcgactgaat tcgatgccga gcgcctttta ttccgtaaat ctggtggcgc
    17401 gtaaaccgga gaagcgtact ccacagacca acagctacgc gcggaagttt ctgatgaact
    17461 cgcaatggcg tcccgatcgc tgtgccgtca ttgccggggc gctgcgttac ccacgttatc
    17521 gctggtacga ccgttttatg atcaagctga ttatgaagat gtcaggcggt gaaacggata
    17581 cgcgcaaaga agttgtctat accgattggg agcaggtggc gaatttcgcc cgagaaatcg
    17641 cccatttaac cgacaaaccg acgctgaaat aagcataaag aataaaaa
//
LOCUS       DAFGPF010000102        17677 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFGPF010000102 DAFGPF010000000
VERSION     DAFGPF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17677
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.102"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(56..469)
                     /gene="hns"
                     /locus_tag="LSX49_003838"
     CDS             complement(56..469)
                     /gene="hns"
                     /locus_tag="LSX49_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HBL7170194.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ"
     gene            1073..1690
                     /gene="tdk"
                     /locus_tag="LSX49_003839"
     CDS             1073..1690
                     /gene="tdk"
                     /locus_tag="LSX49_003839"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL7170195.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQAYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYVSVCRKHYKEALEVGSLTAIQERHRHD"
     gene            complement(1976..3023)
                     /locus_tag="LSX49_003840"
                     /pseudo
     CDS             complement(1976..3023)
                     /locus_tag="LSX49_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418698.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(3148..5823)
                     /gene="adhE"
                     /locus_tag="LSX49_003841"
                     /gene_synonym="adhC"
     CDS             complement(3148..5823)
                     /gene="adhE"
                     /locus_tag="LSX49_003841"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBL7170196.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDTTGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
     gene            6300..6947
                     /gene="ychE"
                     /locus_tag="LSX49_003842"
     CDS             6300..6947
                     /gene="ychE"
                     /locus_tag="LSX49_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HBL7170197.1"
                     /translation="MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
     gene            complement(7105..7266)
                     /locus_tag="LSX49_003843"
     CDS             complement(7105..7266)
                     /locus_tag="LSX49_003843"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170198.1"
                     /translation="MSLFSDYSSSSEMHNNLTIDYYLALSSTKGSGITNIISIILQQA
                     QDYDVAKIT"
     gene            7685..9316
                     /gene="oppA"
                     /locus_tag="LSX49_003844"
     CDS             7685..9316
                     /gene="oppA"
                     /locus_tag="LSX49_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HBL7170199.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRAALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
     gene            9402..10322
                     /gene="oppB"
                     /locus_tag="LSX49_003845"
     CDS             9402..10322
                     /gene="oppB"
                     /locus_tag="LSX49_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HBL7170200.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            10337..11245
                     /gene="oppC"
                     /locus_tag="LSX49_003846"
     CDS             10337..11245
                     /gene="oppC"
                     /locus_tag="LSX49_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HBL7170201.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTPGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            11257..12270
                     /gene="oppD"
                     /locus_tag="LSX49_003847"
     CDS             11257..12270
                     /gene="oppD"
                     /locus_tag="LSX49_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppD"
                     /protein_id="HBL7170202.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPEHELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMDICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            12267..13271
                     /gene="oppF"
                     /locus_tag="LSX49_003848"
     CDS             12267..13271
                     /gene="oppF"
                     /locus_tag="LSX49_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HBL7170203.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(13324..13653)
                     /locus_tag="LSX49_003849"
     CDS             complement(13324..13653)
                     /locus_tag="LSX49_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HBL7170204.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(13688..15148)
                     /gene="cls"
                     /locus_tag="LSX49_003850"
     CDS             complement(13688..15148)
                     /gene="cls"
                     /locus_tag="LSX49_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL7170205.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            15291..15464
                     /locus_tag="LSX49_003851"
     CDS             15291..15464
                     /locus_tag="LSX49_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HBL7170206.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            complement(15519..16772)
                     /gene="kch"
                     /locus_tag="LSX49_003852"
     CDS             complement(15519..16772)
                     /gene="kch"
                     /locus_tag="LSX49_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HBL7170207.1"
                     /translation="MSHWTTFKQTATKLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILSKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDEQETKADSKESAQK"
     gene            complement(17072..17368)
                     /locus_tag="LSX49_003853"
     CDS             complement(17072..17368)
                     /locus_tag="LSX49_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HBL7170208.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            17592..>17677
                     /locus_tag="LSX49_003854"
     CDS             17592..>17677
                     /locus_tag="LSX49_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309779.1"
                     /note="membrane spanning protein in TonB-ExbB-ExbD
                     complex; transduces proton motive force of the cytoplasmic
                     membrane to outer membrane transporters; involved in the
                     transport of ron-siderophore complexes, vitamin B12 and
                     colicins; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HBL7170209.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLL"
BASE COUNT         4527 a         4083 c         4355 g         4712 t
ORIGIN      
        1 acaataaaaa atcccgccga tggcgggatt tttagcatgt gcaatctaca aaagattatt
       61 gcttgatcag gaaatcgtcg agggatttac cttgctcatc cattgctttt ttgattacag
      121 ctggagtacg gccctggcca gtccaggttt tagtttcgcc gttttcgtca acgtagctat
      181 attttgccgg acgctgagca cgcttagctt tggtgccaga tttaacggca gcaaggctat
      241 tcagcagttc gttcgggtca ataccgtcag cgatcagcat ttcgcgatat tgctgcagtt
      301 tacgagtgcg ctcttcaact tcagcagcag ccgcgctttc ttcttcgcga cgttcgttaa
      361 caacaacttc taatttttcc agcatttctt ccagcgtttc aagtgtacat tctcttgcct
      421 gcgcacgaag agtacggatg ttgttcagaa ttttaagtgc ttcgctcatt gtagtaatct
      481 caaacttata ttggggtggt ttgttgaggt aataatagag ccttaaattc agttgtgcaa
      541 tagccaggaa tgtaaggaat tcaaaattgt tctttatttt gtgccgccaa taaatatctt
      601 ttcataaaat tagccagaaa agacgcggca tatagcccta tttgcaccga tgatttcgca
      661 gcacgtgagg ttaaaacttc ctgattcatg tcacatttta tggggagata atcgtaggct
      721 gacgaccttt cagtcttctg tattagtcgt gtttacgaga attccctatt aagcgaatga
      781 tgaaaagtag aacagtcgca ataagagcag ggacttagta ttgcactatc tcctggaggt
      841 caacagaggg ctattacatg cgcaacaggt taaagattgt gaatagttac cggcagtcat
      901 ttacccgctt ataacaagcg aggcagttgt aatgatagct cagaaggatt atgcaaggct
      961 tcgtaaggga gaacgcatat accacttctg tgcatactgt tgagctgaaa aactgacgaa
     1021 ttatgataaa ctccagccaa ctttatttca tatcattgag ggcctgtggc tgatggcaca
     1081 gctatatttc tactattccg caatgaatgc gggtaagtct acagcattgt tgcaatcttc
     1141 atacaattac caggaacgcg gcatgcgcac tgtcgtatat acggcagaaa ttgatgatcg
     1201 ctttggtgcc gggaaagtca gttcgcgtat aggtttgtca tcacctgcaa aattatttaa
     1261 ccaaaattca tcattatttg atgagattcg tgcggaacat gaacagcagg caattcattg
     1321 cgtactggtt gatgaatgcc agtttttaac cagacaacaa gcatatgaat tatcggaggt
     1381 tgtcgatcaa ctcgatatac ccgtactttg ttatggtcta cgtaccgatt ttcgaggtga
     1441 attatttatt ggcagtcaat acttactggc atggtccgac aaactggttg aattaaaaac
     1501 catctgtttt tgtggccgta aagcaagcat ggtgctgcgt cttgatcaag caggcagacc
     1561 ttataacgaa ggtgagcagg tggttattgg tggtaatgaa cgctacgttt ctgtatgccg
     1621 taaacactat aaagaggcgt tagaagtcgg ctcattaacg gctattcagg aaaggcatcg
     1681 ccacgattaa taagaatttc tttactgaca gggtgagcag ggcgctttta tccctgtcag
     1741 ttcgttttac gcacttcttc cgggctatac acccttctcg gcagtttttt aacgccgtta
     1801 tacgcctcac agagcgctta tacaccgaca ttgacttgta acctgtaaag tacaatatcg
     1861 ctgtgtgtag gcgttataca tcgtcgcaaa tatgatgaag gacaatgctg ccggtttatg
     1921 gaaaagttgc tttgggaaaa taaaaaacgg ccccagaagg ggtaatgcca gtcagttaag
     1981 caactgactg gctctttttc ggggctgtgg agtatttcca gggcctctcc tttatcactc
     2041 tcgggaaggc cctttctctt cttgtcggta atttcactag ttgtcccata cttgcaagat
     2101 cgcgcatcag ctccggtata cgtcccgggg aagcgcatgg cgtccgtcat cgacgtcagc
     2161 agatggcaga cttttccttt gcgcgtcacg gtcagcaggc ggactgtcac ctcatttccc
     2221 agtcccggcc acttttttcg tgcctgcggg ctggtgttca gcttcaccag atgatcgcct
     2281 ttacccagtt ttctgatctc ttcatattgc gctccctttc tgagagggat catccagtgg
     2341 cggtgttctc ccgccaggct ccaggtattt aacagtccca gtgagtaata acctttatcc
     2401 attaacgtca gggtgttatc gccggtttgt tctataagtt gctcagcaag ctcattttcg
     2461 ctgttcttca tcgtgccgaa ggctgcagcc gtcagcagat ggctggtcag ttccatctgg
     2521 cagaccattt tgacctgcag gtagagcgcc gggttcccgg catgtgtctg gcgggggaag
     2581 gctgcatcgt tctctggtgt atccggtgtg cgccagaaca caccatcgat ggccagcagg
     2641 gtcaggccgc accagtgcgg atgcggcgtg gtgttatgcc agagctgcgc tgttttcgtg
     2701 aacacgcggc ggacagcctc aattcccaga cgctggcggg tctgaataac ggcactgggg
     2761 gcaacgaagg ggcgattgcc cggcagcatg atatccaggc gattcacaat ctggtgaaga
     2821 ggttctttac gctcaagcgc catgccaaca atacaccaga ccatcatttc gaggggaaga
     2881 cggcgcttgc gtagcgttac agtacctgat tcggcaaggc aacgagagat gagttcgggg
     2941 tcgaggtaat cccccagaga agtcagtggg ttacgcagag aatcgtaacg ggataccaaa
     3001 tcaagggcct gtccaatgag cataaaaaaa tccggaaacg agtgagcgtt tccggattct
     3061 tacacagcca ctggatcggt caactgatcc ttaactgact ggcattaccc cagaaggggc
     3121 cgttatgttg ccagacagcg ctactgatta agcggatttt ttcgcttttt tctcagcttt
     3181 agccggagcg gcttctttct tcgctgcagt ttcgccttct acataatcac gaccgtagta
     3241 agtatccagc agaatctgtt tcagctcgga gatcagcggg taacgcgggt tagcgccggt
     3301 gcactggtca tcgaatgcat cttcagacag tttatccacg ttcgccagga agtctgcttc
     3361 ctgaacgcca gcttcacgga tagatttcgg aatacccagt tcagctttca gtgtttccag
     3421 ccatgccagc agtttctcga tcttagcagc agtacggtcg cccggtgcgc tcagacccag
     3481 gtggtcagca atttcagcat aacgacggcg agcctgcgga cggtcatact ggctgaatgc
     3541 agtctgcttg gtcgggttgt cattcgcgtt gtagcgaata acgttacaaa tcagcagggc
     3601 gtttgccaga ccgtgcggaa tatggaactg ggaacccagt ttgtgcgcca ttgagtgaca
     3661 tacacccagg aaggcgttcg caaacgcgat acccgcgata gtcgctgcac tgtgaacacg
     3721 ttcacgcgct accggatttt tagacccttc gtggtaggac gctggcagat attctttcag
     3781 tagtttcagt gcctgcagag cctgaccatc agagaactca gatgccagta cagaaacata
     3841 agcttccatg gcgtgagtta ctgcgtccag accaccgaaa gcacacaggg acttcggcat
     3901 gtccataaca aggttggcgt cgacaatcgc catatccggg gtcagtgcat agtctgccag
     3961 cggatatttc tgaccagtag tgtcgtcagt tacaaccgca aacggagtga cttcagaacc
     4021 tgtaccagaa gtggtggtga cagcgatcat tttcgctttc acacccattt tcgggaactt
     4081 gtagatacgt ttacggatat ccataaagcg cagcgccagt tcttcgaagt gagtttccgg
     4141 atgttcgtac ataacccaca tgatcttcgc agcgtccatc ggggaaccac cacccagcgc
     4201 gataatcacg tctggtttga aggagtttgc cagttctgca cctttacgaa cgatgctcag
     4261 ggtcgggtca gcttctactt cgaagaagac ttcagtttca acgcctgctg ctttcaatac
     4321 ggaagtgatc tgatcagcat agccattgtt gaacaggaag cggtcagtca cgatgagcgc
     4381 acgtttgtgg ccatcagtaa tcacttcatc cagcgcgatt ggcagggagc cacggcggaa
     4441 gtagatagat ttcggaagtt tgtgccacaa catgttttca gctcgcttag caacggtttt
     4501 cttgttgatc aggtgtttcg gaccaacgtt ttcagagatg gagttaccac cccaggaacc
     4561 acaacccaga gtcagggaag gtgcgagttt gaagttatac aggtcaccga taccaccctg
     4621 agaagccggg gtgttaatca ggatacgagc cgttttcatt ttctgaccga agtaagaaac
     4681 gcgagccggt tggttatcct ggtcagtgta caggcaagag gtatgaccga taccgcccat
     4741 agcaaccagt ttttctgctt tttctaccgc gtcttcgaaa tccttagcac ggtacattgc
     4801 caaagtcggg gacagttttt catgtgcgaa cggttcgctt tcatcaacaa cggttacttc
     4861 accgatcaga atcttggtgt tttctggtac agagaagcct gccagttcag caattttata
     4921 ggctggctga ccaacgatag ccgcgttcag cgcaccgttt ttcaggataa cgtcctgaac
     4981 agctttcagc tctttaccct gcaacagata gccaccgtgg gttgcgaaac gttcacgtac
     5041 tgcgtcataa acagagtcaa caacaacaac agactgttca gaagcacaga ttacgccgtt
     5101 gtcgaaggtt ttggacatca gtacagatgc aactgcacgt ttgatatcag cagtttcatc
     5161 gataacaact ggagtgttgc ccgcgcctac gccgatagct ggtttaccgg agctgtatgc
     5221 ggctttaacc atgcccggac caccagtcgc gaggatcagg ttgatgtctg ggtggtgcat
     5281 cagtgcgtta gacagctcaa cagaaggttg atcgatccag ccgatcagat ctttcggagc
     5341 accggcagcg atagcagcct gcagaacgat atcagccgct ttgttggttg catcttttgc
     5401 acgcgggtgc ggggagaaga taatggcgtt acgggtcttc aggctgatca gtgatttgaa
     5461 gatagcagtt gaagtcgggt tagtggtcgg aacgatgccg caaataatac cgatgggttc
     5521 agcgatagta atggtaccaa aagtgtcgtc ttcagacaga acaccacagg ttttttcatc
     5581 tttataggcg ttgtagatat attcagaagc aaagtggttt ttgatcactt tatcttcgac
     5641 gatacccatg ccggattcgg caacggccat tttcgcgagt gggattcgag catctgcagc
     5701 agccagagcg gcggcgcgga agattttgtc tacttgctct tgagtgaaac tggcatattc
     5761 acgctgggct ttttttacac gctctacgag tgcgttaagt tcagcgacat tagtaacagc
     5821 cataatgctc tcctgataat gttaaacttt tttagtaaat catctgctcg aatacgagag
     5881 tatagtcagt gcggtgatga tttgcttaac cgatggaaat caaaagctta ctcgcgctca
     5941 cactcactgt gatttactaa aagagtttaa acattagagt tattatctct aatgcgtcac
     6001 ttccaggtgg cgtaagcaag attactcact tctgggtact gattacgtga tcaagatcaa
     6061 atttttgcaa agctgacacc tttcagcatg gcttttcgcc attatagcta acagttaaca
     6121 aattgtagta tgatttgttg gctacattag catgttttgc acaactagat aacaataacg
     6181 aatgatagca attttaagta gttaggaggt gaaaaatgct gtcaaaaggc gtattgtcag
     6241 cgcgtctttt caaccttatt tatggctaac attatccggc ttttgcttcg gagctaaccg
     6301 tgattcagac cttttttgat tttcccgttt acttcaaatt tttcatcggg ttatttgcgc
     6361 tggtcaaccc ggtagggatt attcccgtct ttatcagcat gaccagttat cagacagcgg
     6421 cagcgcgaaa caaaactaac cttacagcca acctgtctgt ggccattatc ttgtggatct
     6481 cgctttttct cggcgacacg attctacaac tttttggtat atcaattgat tcattccgta
     6541 tcgccggtgg catcctggtg gtgacaatag cgatgtcgat gatcagcggc aagcttggtg
     6601 aggataaaca gaacaagcaa gaaaaatcag aaaccgcggt gcgtgaaagc attggtgtgg
     6661 tgccattggc gttgccgttg atggcggggc caggggcgat cagttctacc atcgtctggg
     6721 gtacgcgtta tcacagcatt agctatctgt ttggtttctt tgtggctatt gcattgttcg
     6781 ctttatgttg ctggggattg tttcgcatgg caccgtggct ggtacgagtt ttacgccaga
     6841 ccggcatcaa cgtgattacg cgtattatgg ggctattgct gatggcgttg gggattgaat
     6901 ttatcgttac tggtattaag gggattttcc ccggcctgct taattaattc ctttcaaatg
     6961 aaacggagct gccatgctcc gtttacttcg tcattatttt tactttgttc ctgcgcagtt
     7021 atcaaaagca aaaggaatag gtaaaaatat tcttctcaaa ttacagttag ttataaggat
     7081 ttccttaact gcttctcctc accatcatgt tattttcgcc acatcataat cctgggcttg
     7141 ctgaagaata attgaaatga tattagtaat tccactgcct ttggtagagg aaagtgctaa
     7201 ataataatca attgttaaat tattgtgcat ttcactactg gaactgtaat cagaaaagag
     7261 agacatgctt aactaacctc tatttgattg aattgaaaga tgtttgttaa ggcatggatg
     7321 caagctatag attctggtac ggtcaataaa agagaattgc ttaacaattt tgcaaaatgt
     7381 attggcgagt aagaaccgca tttggtactt tccgggcaac cgccaggcga ttctttattg
     7441 gtaatgagaa taattaacaa ttaaagaccg tcgcgaaaga ataatgtgtc tcgacagggg
     7501 agacacagta cgaatcgaca taaggtgatc gtctgaatca ccagaataaa taaagtcggt
     7561 gatagtaata cgtaacgata aagtaacctg acagcagaaa gtctccgagc ctgtgcaggg
     7621 tcccaatccg ggattacaca tgctggttaa taccagtaat tataatgagg gagtccaaaa
     7681 aacaatgacc aacatcacca agagaagttt agtagcagct ggcgttttgg ctgcgcttat
     7741 ggcagggaat gtcgcgctgg cagctgatgt acccgcaggt gtcacactgg cggaaaaaca
     7801 aacgctggta cgtaacaatg gttcagaagt tcagtcatta gatccgcaca aaattgaagg
     7861 tgttccggag tctaatatca gccgagacct gtttgaaggc ttactggtta gcgatcttga
     7921 cggccatccg gcacctggcg tcgctgaatc ctgggataat aaagacgcga aagtctggac
     7981 cttccatttg cgtaaagatg cgaaatggtc tgatggcacg ccagtcacag cacaagactt
     8041 tgtgtatagc tggcaacgtt ctgttgatcc aaacactgct tctccgtatg ccagttatct
     8101 gcaatatggg catatcgccg gtattgatga aattcttgaa gggaaaaaac cgattaccga
     8161 tctcggcgtg aaagctattg atgaccacac attagaagtc accttaagtg aacctgttcc
     8221 gtacttctat aaattacttg ttcatccatc aacttcaccg gtgccaaaag ccgctatcga
     8281 gaaattcggc gaaaaatgga cccagcctgg taatatcgtc accaacggtg cctatacctt
     8341 aaaagattgg gtcgtaaacg aacgaatcgt tcttgaacgc agcccgacct actggaacaa
     8401 cgcgaaaacc gttattaacc aggtaaccta tttgcctatt gcttctgaag ttaccgatgt
     8461 caaccgctac cgtagtggtg aaatcgacat gacttataac aacatgccga tcgaattgtt
     8521 ccagaagctg aaaaaagaga tcccggacga agttcacgtt gatccatacc tgtgcactta
     8581 ctattacgaa attaacaacc agaaaccgcc atttaatgac gtgcgtgtgc gtaccgcact
     8641 gaaattgggt atggaccgcg atatcattgt taataaagtg aaagcgcagg gcgacatgcc
     8701 cgcctatggt tacactccac cgtatactga tggcgcaaaa ttgactcagc cggaatggtt
     8761 tggctggagc caggaaaaac gtaacgaaga agcgaaaaaa ctgctggctg aagcgggtta
     8821 taccgcagac aaaccgttga ccatcaacct gttgtataac acctccgatc tgcataaaaa
     8881 gctggcgatt gctgcctctt cattgtggaa gaaaaacatt ggtgtaaacg tcaaactggt
     8941 taaccaggag tggaaaacgt tcctcgacac ccgtcaccag ggcacttttg atgtggcccg
     9001 tgcaggctgg tgtgcagact acaacgaacc aacttccttc ctgaacacca tgctgtcgaa
     9061 cagctcaatg aataccgcgc attataagag cccggccttt gacagcatta tggcggaaac
     9121 gctgaaagtg actgacgagg cgcagcgtgc agctctgtac actaaagcag aacaacagct
     9181 ggataaggat tcggccattg ttcctgttta ttactacgtg aatgcgcgtt tggtgaaacc
     9241 gtgggttggt ggctataccg gcaaagatcc gctggataat acctacaccc ggaatatgta
     9301 cattgtgaag cactaatggc aatacgtggg gcaggagtgt cctgctccac ggtgtctgat
     9361 ttttatcgca ttacagaagg cacaggccag aaggtagggc aatgttaaaa tttattctac
     9421 gtcgctgtct ggaagcgatt ccgacgctat ttattcttat tactatttcg ttctttatga
     9481 tgcgcctcgc gccgggcagt ccttttaccg gcgaacgtac tttaccaccg gaagtgatgg
     9541 ccaatatcga agcgaaatat catcttaatg atccgatcat gacacagtat ttcagctacc
     9601 tgaaacaact ggcgcatggc gatttcggtc catcgtttaa atataaagat tattcggtca
     9661 atgacctggt tgcatccagt tttcccgttt ctgccaaact gggagctgca gcattttttc
     9721 ttgcggtaat actgggtgtt agtgctggcg ttattgccgc attaaagcaa aacaccaaat
     9781 gggactatac cgtgatgggg ctggcaatga ccggggttgt tatccccagt tttgtggttg
     9841 cgccattatt agtcatgata tttgcgatca ttttgcattg gctgccgggc ggtggctgga
     9901 atggtggagc gcttaaattc atgatattgc caatggtggc gttatcactc gcctatatcg
     9961 ccagtattgc gcgtattacc cgtggctcta tgattgaggt tttacactcc aactttattc
    10021 gtactgcccg ggcgaaaggg ttacctatgc ggcggatcat tttacgccac gcattaaaac
    10081 ctgctctgtt acccgtgctc tcctatatgg ggcccgcatt tgtcggcatt attaccggtt
    10141 cgatggtcat cgaaaccatt tatggtttac cggggattgg gcaattgttc gttaatggcg
    10201 cattgaaccg tgactattcc ttagtgttaa gtctgaccat tctggttggc gcgttaacca
    10261 ttttgtttaa tgccattgtc gatgtgctat atgcggttat cgacccgaaa atccgttact
    10321 gatactggag ctcgcgatga tgttaagtaa gaaaaacagc gagacgctgg aaaatttcag
    10381 tgaaaagctg gaggtcgaag ggcgcagctt gtggcaggac gcacgtcgac gttttatgca
    10441 taaccgtgcg gcggttgcca gtctgatagt gctggtgctg atcgcgttat ttgtaatcct
    10501 ggcaccgatg ctttcgcagt ttgcctatga cgatactgac tgggcgatga tgtccagcgc
    10561 cccggatatg gagtccggtc actactttgg tactgactca tccggtcgcg acctgcttgt
    10621 gcgcgttgcg attggcgggc gtatctcact catggtcggt gttgctgcgg cactggtggc
    10681 agtggtcgtg gggacacttt atggttcgct ttccggttat ctgggcggta aagtggattc
    10741 ggtaatgatg cgtctgctgg aaatcctcaa ctccttccca ttcatgttct tcgtcatttt
    10801 gctggtgacc tttttcggtc aaaacatcct gctgattttc gtggcgattg gcatggtttc
    10861 ctggctggat atggctcgta ttgtgcgtgg gcaaaccctg agtctgaagc gcaaagagtt
    10921 tattgaggcg gcacaagttg gcggtgtatc gacgccgggc attgttattc gccacattgt
    10981 gccgaacgta ctcggtgtgg tggtggtcta tgcgtcgctt ctggtgccca gcatgatcct
    11041 ctttgaatct ttccttagct tcctgggatt aggtacacaa gagccgttaa gcagctgggg
    11101 tgcattgctg agtgatggcg cgaactcgat ggaagtctct ccatggttac tgttgttccc
    11161 agcgggattc ctcgtggtaa cgctgttttg tttcaacttt atcggcgatg gcttgcgtga
    11221 tgccctcgac ccgaaagatc gttaaggagt gcagccatga gcgtaattga aactgcaact
    11281 gtgccgctcg cacaacaaca ggctgacgca ctgctgaacg tgaaagattt gcgtgtcacc
    11341 tttagtaccc cggatggcga cgtcacggcg gtcaatgatt tgaatttttc gctacgtgcc
    11401 ggagaaacgc tgggcatcgt aggtgagtct ggttcgggca aatcgcaaac cgcattcgcg
    11461 ttgatgggcc tgttagctgc caacggacgt attggcggat cggcaacctt caatgggcgt
    11521 gaaatcctca atttgccaga gcatgaactc aataaactgc gagctgaaca aatctcaatg
    11581 atttttcagg acccaatgac ttcgttgaat ccctatatgc gcgtcggtga gcagttgatg
    11641 gaagtgctga tgctgcataa gaacatgagc aaagctgagg cgtttgaaga atcggtgcgg
    11701 atgctcgatg cggtaaaaat gccggaagcg cgtaaacgca tgaaaatgta cccgcacgaa
    11761 ttttctggcg gcatgcgtca gcgagtcatg attgcgatgg cattgctatg tcgacctaag
    11821 ctgctgattg cggatgaacc cactactgcg ctggacgtca ccgtacaggc gcagatcatg
    11881 acgctattga atgaactgaa gcgggaattt aataccgcca tcattatgat tacccacgat
    11941 cttggcgtgg tggcggggat ctgcgacaaa gtgctggtaa tgtacgccgg gcgcacgatg
    12001 gaatatggca acgcgcgcga tgtcttttat caacccgtac atccttattc tatcggtttg
    12061 ctcaacgcgg tgccgcgtct cgatgcggaa ggtgaaacaa tgttgactat tccgggtaat
    12121 ccgccaaacc tgctgcgatt accgaaaggt tgcccgttcc agccacgttg tccgcatgcg
    12181 atggatattt gtagtagcgc accgccgctg gaagagttta cgcctggccg tctgcgtgct
    12241 tgctttaaac cggtggagga actgttatga atgctgtaac cgaaggaaga aaagtcctcc
    12301 tcgaaatcgc cgatctgaaa gtgcactttg aaatcaaaga tggcaaacag tggttctggc
    12361 aaccgccgaa aacgctcaaa gccgtcgatg gtgtaactct tcgcctgtat gaaggggaaa
    12421 cattaggtgt ggtaggggaa tcgggatgcg gtaagtccac ctttgctcgc gccatcattg
    12481 gcctggttaa agcgaccgac ggtcatgttg cctggttagg taaagagttg ctgggcatga
    12541 agcccgatga atggcgtgcc gtacgcagtg atattcagat gattttccag gatccgttgg
    12601 catcgctgaa cccgcgtatg accatcggcg agatcatcgc tgaaccactg cgtacttatc
    12661 atccgaaaat gtcacgccag gaagttcgcg agcgcgtgaa ggcgatgatg ctgaaagtcg
    12721 gtttgttgcc taacctgatt aaccgctatc cgcatgagtt ctccggtggg cagtgccagc
    12781 gtatcgggat tgctcgcgct cttattcttg aaccgaagct gattatctgt gatgagccgg
    12841 tgtcggcgct ggacgtgtca attcaggcgc aggtggtcaa cctgctccag cagttgcaac
    12901 gtgagatggg attgtcatta atttttatcg ctcacgacct ggccgtggta aaacacattt
    12961 ccgatcgtgt gctggtgatg tatctcggcc atgcggtaga actggggacc tatgatgagg
    13021 tctaccacaa tccgctacat ccttacacca gggcattgat gtcggcagtc cccatacctg
    13081 atccggatct ggagaagaac aaaaccatcc agttactgga aggggaatta ccgtcgccga
    13141 tcaacccgcc ttccggttgt gttttccgta cccgttgtcc gattgcaggt ccggagtgcg
    13201 ccaaaacacg tcctgtgctg gaagggagtt tcagacacgc cgtttcttgc ctgaaagtcg
    13261 atccgcttta aaagcaataa gggctgacag ttgtcagccc ttattcacgc caaaagcgat
    13321 tatttattcc cgccagatga tatggcaaag tttgtgatct ttttcgcggc ataacagaat
    13381 gcgcgcgaaa acatcgttga tttcaccatc ttcactgtcc gccagaccaa tcaccacttc
    13441 ggcaaaaaag tccgggttca aatcgaaatc aacatgttcc tgccagtctt ccgccggatc
    13501 gaataactcc gcgccgccgc gctcttcaaa ctgaagattg aacagcagaa catcagctgg
    13561 atcgagattg tcggcagcca gttcgagaaa aatatcgtag gcctgctcaa gcgtttcatc
    13621 ttcagtcagg cgattgttta gatccatatc catagtcact acctgtttaa cctctgttgg
    13681 cgacgtttta cagcaacggg ctgaagaagt aaaacagtcg ctcggcgaca cgttgccata
    13741 atggacgttt tagccataaa cgggcatcga gcagacgaga acgcgaaata taatcgtcct
    13801 gaacggcggc gaggtctgca ccaaaacctt tatcgtcgat tgccagggta atctcgaaat
    13861 ttagccacag actacgcata tcaaggttaa cggtgccaac cagacttagt tctccatcga
    13921 ccagcacgct cttggtatgc agtaacccgc cttcaaactg ataaatttta accccagcag
    13981 ccagcagttc tgtaaagaat gcgcgactgg cccagccgac cagcatcgag tcattttttc
    14041 gcggaaggat aatactgaca tccaccccgc gctgcgccgc cgtgcaaatc gcatgaagta
    14101 aatcatcgct tggcacaaaa tagggcgttg tcatgatcaa atattcacga gccgaataag
    14161 cagcagtcaa taatgcctgg tgaatgagat cttccggaaa gccggggcca gaagcaattg
    14221 tgtgaatggt gtgaccactg gcctgctcaa acggcataat attgacatct ggtggcggcg
    14281 gcagaatacg tttcccggtt tcaatctccc agtcgcagga ataaataatc cccatcgcgg
    14341 tggcgatggg gccttccata cgcgccatca gatcaatcca ttgccctaca cccgcatctt
    14401 gtttgaagta gcgagggtcg accatattca tgctgccggt gtacgcgatg taattatcga
    14461 tcatgatcat cttgcgatgt tggcgcaggt ccatacggcg taaaaacaca cgcatcagat
    14521 tgacctttaa ggcttcgaca acttcaatac cggcattacg cattagctcg ggccacgggc
    14581 tgcggaaaaa agccacactc ccggcggagt cgagcatcaa tcggcaatga ataccgcgcc
    14641 gtgcagcggc cattaatgat tcagccacct ggtccgccat gccgccgggc tgccagatat
    14701 aaaacaccat ctcaatatta tggcgcgcga gctggatgtc gcggattaac gcctgcatca
    14761 catcatctga ctcggtcatc agttgtagct gattcccttt gaccccagcg atcccctgac
    14821 gacgctcgca aagcttgaat aatggcgcag cgacactgct attttcttcg gcgaagatat
    14881 gcttacaggc tttaaggtcg ttaagccatt ttgcggtgga aggccacatc gctctggcgc
    14941 gctcagcgcg gcgtttgcct aaatggagct cgccaacggc aagataggca ataattccga
    15001 ctaacggcag aatgtaaata atcaacagcc aggccatcgc ggagggaact gcgcgtcgtt
    15061 tcattagaat gcgtaaagtt acgcctgcaa tgagcaacca gtatcccaga atggccaacc
    15121 aactcaccaa cgtataaacg gttgtcatag attagaaatc cttttgaaag cgcattgtta
    15181 tgagtttacg catatggatt catctggcaa ataaaaacga gggaaaagca ctggtcagcg
    15241 tcaggggcgg gggtataatg accattctgt tgttgcatag agtagttaac atgaagcgga
    15301 gtagaacgga agtggggcgc tggcgcatgc agcgtcaggc tagccgacgt aaatcgcgtt
    15361 ggcttgaggg gcagtcgcgc cgaaatatgc gtatccacag catcaggaag tgcattctaa
    15421 acaaacagcg taactcgtta ttgtttgcga tctacaatat ctaaatgtac tgggcaccat
    15481 tgcggtgccc aataagttta ctcttccgtc tttaaactct atttttgcgc cgattcttta
    15541 ctgtcagctt tcgtttcttg ttcatcgtta tcgctgaaaa tgccatgacc ggagttcaac
    15601 aacattgaaa cgagcatatc attattaatc tcttcaccat ttaaaactcg cgccagaatt
    15661 tcgctgccaa acagttgtgg tgagagaatg atatccggat gtaccatctt aatcttattc
    15721 aggtttttgc tatcactgac ggcaagaact gttttgacat cactgctcat atcttttgcc
    15781 gagagtacaa caaacgcgtt atctgcatcg ttatcactca gcgccagaat ggcccggcaa
    15841 cgatcgattc ccgctttctt taacactgaa ctgtcattac tgtcaccggg gataacatcg
    15901 gcgttatcgc ctaagcgttg ctcaagttgc ttgatatcat cttcaggcaa gttgctgata
    15961 accgttacgt tttgtccgcg ttgattcagt tgcagaatcg tattgatggc gagaatcgaa
    16021 tgtccgcaaa caataaaatg atctttacga tgcattgtat gattgtttcc ttttacaagt
    16081 ttgttgaatc ccccgcggat aagcggacca aaaattgagg tcatagatgt ggcaaaaacg
    16141 gtaatgccgg aaataatgac cgaaatagtg aacaatcgtg ctgattcaga aacagggaca
    16201 atatcgccat agccgacggt tgacatggtt tctatcgaaa aatagaacgc ggtcatcaaa
    16261 ctttctattc gcggattaaa accttcgctt aaataaagcg caccgtaagt ggagtaaaac
    16321 agtaacgtcg tgaaactaat aaatgcgaaa attgtcccgg ctgctgcgct actgtgggag
    16381 aagtctttgc tcagtatcag caaaaacacc agcgtaaaaa tgcaaaatcc aatactaaat
    16441 ttcagccagg gataaaaatg cagagtgtaa attagcgcta tcaacaacaa aatgatactg
    16501 attgcccatg cgagctttgc ccggaacagt aagccaatgg agttcaggac aagaaatacg
    16561 ccgagcataa atagtggggc gtttgccagc aaggagagat ccagctctga aaatgctttg
    16621 atatggaaaa tatcaagcaa attgaccgac ataccataga ttgttttaaa aataagcaat
    16681 ccatttaaaa agacggccag cgcgagaatg tcgtgccgta gggtcaccca taactttgtt
    16741 gctgtttgtt tgaatgtagt ccagtgactc actgatacct ctgtaaccac aattttgttt
    16801 aattatctca acgtgcacat tttctgaaca tacatgcagc tcgtgaatgt gttaaacaat
    16861 agtagatgac tttatccgca gtaatcaaag gttttgagtg agcaactctg cgtcaggaaa
    16921 gggcattttc ctgaatatgt tcacatcata taaagaaata cagataaagt tattatctgc
    16981 ttgtggtggt gaatgcactg accgacctat aaggaaaggc caaacaagaa cacggttgca
    17041 aaaaccgtgc ccttaaatat tgaatttcta ttcagaacac tttcttaaat ggtttcactg
    17101 aaacgtgttc atagactcct gccgctacgt acgggtcagc atcggcccag gcctgagctg
    17161 cttccagcga ctcaaattca gcaataacgg ttgagccagt aaatcccgca gcccctggat
    17221 cgttactgtc taccgctggc attggaccgg cggtcaacaa acgaccttca tcatgcagta
    17281 actgtaaacg tgctagatgt gccggacgaa cggaaaggcg tttttcgagg ctatcagctt
    17341 tgtcttgagc gtaaataaca tacaacacag gcacaactcc ttgttcggga aagttgtaaa
    17401 gtacgttatt tgaaagggcg aagatctgca acggaaagat gatgtctttg ttaagaccat
    17461 gcataaagta aggtcaatta cgccaaaaat gacattttca ctgatcctga tcgtcttgcc
    17521 ttattgaata tgattgctat ttgcatttaa aatcggggcc tggtttttct actgaaatga
    17581 ttatgacttc aatgaccctt gatttacctc gccgcttccc ctggccgacg ttactttcgg
    17641 tctgcattca tggtgctgtt gtggcgggtt tgctcta
//
LOCUS       DAFGPF010000103        17428 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFGPF010000103 DAFGPF010000000
VERSION     DAFGPF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17428
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.103"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(111..842)
                     /gene="rlmB"
                     /locus_tag="LSX49_003855"
     CDS             complement(111..842)
                     /gene="rlmB"
                     /locus_tag="LSX49_003855"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBL7170210.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(933..3374)
                     /gene="rnr"
                     /locus_tag="LSX49_003856"
     CDS             complement(933..3374)
                     /gene="rnr"
                     /locus_tag="LSX49_003856"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313182.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBL7170211.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVSDWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKPKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(3413..3838)
                     /gene="nsrR"
                     /locus_tag="LSX49_003857"
     CDS             complement(3413..3838)
                     /gene="nsrR"
                     /locus_tag="LSX49_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HBL7170212.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(4043..5341)
                     /gene="purA"
                     /locus_tag="LSX49_003858"
     CDS             complement(4043..5341)
                     /gene="purA"
                     /locus_tag="LSX49_003858"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBL7170213.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGLEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(5445..5642)
                     /locus_tag="LSX49_003859"
     CDS             complement(5445..5642)
                     /locus_tag="LSX49_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HBL7170214.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(5724..6728)
                     /gene="hflC"
                     /locus_tag="LSX49_003860"
     CDS             complement(5724..6728)
                     /gene="hflC"
                     /locus_tag="LSX49_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HBL7170215.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(6731..7990)
                     /gene="hflK"
                     /locus_tag="LSX49_003861"
     CDS             complement(6731..7990)
                     /gene="hflK"
                     /locus_tag="LSX49_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HBL7170216.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTDPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(8076..9356)
                     /gene="hflX"
                     /locus_tag="LSX49_003862"
     CDS             complement(8076..9356)
                     /gene="hflX"
                     /locus_tag="LSX49_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBL7170217.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLDDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(9432..9740)
                     /gene="hfq"
                     /locus_tag="LSX49_003863"
     CDS             complement(9432..9740)
                     /gene="hfq"
                     /locus_tag="LSX49_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBL7170218.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(9826..10776)
                     /gene="miaA"
                     /locus_tag="LSX49_003864"
     CDS             complement(9826..10776)
                     /gene="miaA"
                     /locus_tag="LSX49_003864"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBL7170219.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLNIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(10769..12616)
                     /gene="mutL"
                     /locus_tag="LSX49_003865"
     CDS             complement(10769..12616)
                     /gene="mutL"
                     /locus_tag="LSX49_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710035.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBL7170220.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRNMDVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAVREPVAPRYTPAPSSGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLSLPVAERWLRQAQLTPGEVPVCAQPLLIPLRLKVSGEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(12626..13957)
                     /gene="amiB"
                     /locus_tag="LSX49_003866"
     CDS             complement(12626..13957)
                     /gene="amiB"
                     /locus_tag="LSX49_003866"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HBL7170221.1"
                     /translation="MMYRIRNWLVATLLLLCAQAGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADAPPSPPPMVAKRVETPAVVAPRVSEPARNPFK
                     TESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNVTI
                     AIARKLRTLLNNDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRSA
                     TGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQADPYLSQAVLDLQFGH
                     SQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEERL
                     LASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(13976..14437)
                     /gene="tsaE"
                     /locus_tag="LSX49_003867"
     CDS             complement(13976..14437)
                     /gene="tsaE"
                     /locus_tag="LSX49_003867"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBL7170222.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(14409..15956)
                     /gene="nnr"
                     /locus_tag="LSX49_003868"
     CDS             complement(14409..15956)
                     /gene="nnr"
                     /locus_tag="LSX49_003868"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBL7170223.1"
                     /translation="MTDHTMKKNPVSIPHTVWYADDIRRGEREAADALGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAIGIDVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLQQAPRESISQLIDHANSH
                     PAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLR
                     LDRWLAGQETKIQRFSAEQLSQWLIPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMGSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLHCAQRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKMSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            15955..17094
                     /gene="queG"
                     /locus_tag="LSX49_003869"
     CDS             15955..17094
                     /gene="queG"
                     /locus_tag="LSX49_003869"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBL7170224.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSESEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGEIPEELRPLMGNRIYGCDDCQLICPWNRYSQLTTEDDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILTALESRKGEH
                     PLLDEHIAWAIAQQIERRNACVVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(17077..17130)
                     /locus_tag="LSX49_003870"
     CDS             complement(17077..17130)
                     /locus_tag="LSX49_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170225.1"
                     /translation="MRFYFYSQAVDESGVTR"
BASE COUNT         3978 a         4950 c         4354 g         4146 t
ORIGIN      
        1 attaagttta aatattaata aaatgaatat ttgcagtacg taattatctt accagctata
       61 gacaaaaaaa aaccatccaa atctggatgg cttttcataa ttcagaggaa ctagctgcgc
      121 tgacgaaccg cttcaaataa gcaaattccg gttgcaaccg aaacgttcag ggaagaaaca
      181 cttcctgcca ttgggatgct gatcaactca tcgcaatgtt cacgggtcag gcgacgcata
      241 ccttcacctt ccgcgcccat caccagcgcc aggcgtccgg tcattttgct ctgatagagt
      301 gtatgatccg cctcgcctgc cgtaccgacg atccagatat tctcttcctg caacatacgc
      361 atggtgcgcg ccagattagt cacccgaatc agcggaacgc tttctgccgc accacaggcc
      421 acttttttcg ccgtggcgtt gagctgtgcg gagcgatctt tcggcacaat caccgcatga
      481 acaccagcgg cgtccgcgct acgcaggcac gcgccgaggt tgtgcggatc ggttacgccg
      541 tcgaggatca gcaggaacgg ttgatcgagc gaagcgatca gatccggcag atcgttttcc
      601 tgatactgcc gtcctggctt cacacgagcg ataatgccct gatgcacggc accgtcgctt
      661 ttctcgtcga gatattggcg gtttgccaac tggataacca cgccctgaga ctcaagggcg
      721 tgaatcagcg gtaacagacg tttatcttca cggcctttta aaataaagac ttcctgaaaa
      781 cgttcagggg cgcgctccag cagggcctgc actgcatgga tgccgtaaat catttcgctc
      841 attaatgtac tcgttgttta cgttttgccg ggagcgccac gcttgcccgg cctacggata
      901 attcaccctc ttctgtttga agagggtaat gatcactctg ccactttttt cttcgccgca
      961 cgcttcgctt tggtcgctgc ggctattttc tgcgttttcg ccgatggctt tttcgctttt
     1021 ctcgcgtctt tcttcgctgc tttcggcttc ggttttttct cgccacggaa ggcgctgtct
     1081 ggctcaaagt tgaccttttt gccgacctga cgccgcttgc cgcctttttt gcctgcatcg
     1141 ccttttttcg ctttctcgcg cgccgtttta ccgacgttgc gcggtgcgcg ttcgctggag
     1201 atcaggctaa agtcgatttt gcgctcgtcc atattaaccg cttcgacgcg aacttccacg
     1261 cgatcgccca ggcgataagt ctgaccgctg gattcaccca tcaggcgttg ccctacctgg
     1321 tcaaagcgat agtagtcatt gtccagcgaa gagacatgga ccagaccatc aatgaacaag
     1381 tcgtccagac ggacgaagaa gccaaagcca gtgacgctgg aaattacgcc tttaaagacg
     1441 ttacctacct ggtcgagcat gaagtcacac ttcagccagt cagacacatc gcgcgttgct
     1501 tcatcggcac gacgttccgc catcgaacag tgctgaccca gttgcagcat ctcttccatc
     1561 gaataatggt agccgccggt ttcagtggtg ttgccctgat gcccctgctc tttcgccagc
     1621 agatatttaa tggcgcggtg caacgtcagg tcaggataac gacgaatcgg cgaagtaaag
     1681 tgcgcatagg actgcaatgc cagaccgaag tgaccacggt tttccggatc gtaaatcgcc
     1741 tgtttcatcg agcgcaaaag catggtttgc agcatttctg catcaggacg atcggcaacc
     1801 gattccagta actctgcata gtcgcgcggt tccggcttgt taccgcccgg caattccagc
     1861 cccagctccg ccagcactga acggaaagag gtaatcgctt cggtgctcgg cttgtcgtga
     1921 atacggaaca gtgccggttc tttggctttc tcaacgaaac gcgccgccga gatattcgcc
     1981 agaatcatgc actcttcaat taacttgtgg gcgtcgttac gctgagtctg ttcgatacgt
     2041 tcaatacggc gttcagcgtt gaaaatgaac ttcgcttctt cgctctcaaa tgagatccca
     2101 ccgcgttctt cacgggcttt atccagcact ttatagaggt tatgtaactc ttcgagatgc
     2161 ttaaccagcg gcgcatactg ctcgcgcaga tcctgatcgc cttgcagtat atgccagact
     2221 ttggtgtagg tcagacgcgc gtgagaactc atcaccgctt cgtagaattt gtagccagtc
     2281 aggcggcctt tcgacgaaac cgtcatctcg cacaccatac acaggcggtc tacctgcggg
     2341 ttgagcgagc acaggccgtt agagagcact tccggcagca tcgggataac ctgcgaaggg
     2401 aagtacaccg acgtaccacg gttacgcgct tctctgtcca gcggtgttgg cggacggaca
     2461 tagtaactga cgtcggcaat tgcgacccac aaacgccagc caccgccgcg ttttttctca
     2521 cagtaaactg catcgtcaaa gtcacgggcg tcttcgccat caatggtgac cagcggtaaa
     2581 tcgcgcagat cgacacggcc cgcttttgct tcttccggca cttcttcttt cagcccggca
     2641 acctgttgct caacagcctg cggccagatg tacggaattt catgggtacg cagagcaata
     2701 tcaaccgcca tgccggtgcc catattatcg cccagcactt cgacgatttt acccaccgct
     2761 ttggtacggc gagtcgggcg ttgagtcagt tcaaccacca ccacaaagcc catccgcgcg
     2821 cccatgatct gatcgggcgg gattaagata tcgaagctca gacggctatc gtcaggaacc
     2881 acaaagccga cgcccgcttc ggtgaagtag cgaccaacaa tctggctggt ttttggcacc
     2941 agtacgcgga caatacgcgc ttcacgacga cctttacggt cagcgcccag cggctgagcc
     3001 agcacctgat cgccatgaat gcaggttttc atctgctcgc tggagagata caaatcatct
     3061 ttacgccctt caactcgcag aaagccgtag ccatcacggt ggccaataac ggtacctttc
     3121 accaggtcga ggcgttccgg cagcgcatag cactgacggc gagtgaagac cagttgacca
     3181 tcgcgctcca tcgcgcgcag gcgtcgacgc aggccttcaa gctgctcttc gccttcaatg
     3241 tgcagttcta ccgccagctc atcacggctg gccggttttt cacgtttggt taaatgttcg
     3301 aggataaatt cccgactagg gatgggattc gcgtattttt cagcttcgcg ttcctggaaa
     3361 ggatcttgtg acatctcggt tcctccgttg tcatctctga tgaagatttt cgtcactcca
     3421 ccagcaataa tttataaagc ggttgattct cttcaaccaa atcggcaagc gtgtagttat
     3481 ccagttccgt cagaaaactt tgcacggcct tagaaagcgc ctgtttcaac cgacaggcag
     3541 gtgtaatgtg gcaaaactca ctgctgcaat tcaccagcga taagggctcc agctcgcgca
     3601 ccacatcacc aatacgtatc gcactcgccg gtttacccaa gcgaatgccg ccattttttc
     3661 cacgaacagc agtcacgtag ccggcacgac taagttgatt gattattttg accatatgat
     3721 tacgggagac gccgtagacg tcagtcactt cagaaatact ggtcatccgc ccttctggca
     3781 atgacgccat gtagatcagc gcacgtaatc cgtaatcagt gaaactcgtt aactgcacat
     3841 caacctcaaa agggaaatcg gggaaaaata catttatatt gatgataaac cagccacaag
     3901 ctgtgtcgct aatttatttc agttcgggga aggaaaaaaa cgaggattta acactgtgtc
     3961 ggatagcgta atggcttaac cgacacagca atgtatcaca ctgttagccc ggcaggcaaa
     4021 atatctgcca tgcgtaccag aattacgcgt cgaacgggtc gcgcagaatc atggtttcag
     4081 tacgatccgg accggtagag atgatatcga tcggcacacc ggtcagctct tcaatgcgct
     4141 tgatgtagtt cagtgccgcc tgcggcaggc cactacgatc tttcacgccg aaggtggatt
     4201 cagaccagcc cggcatggtt tcgtaaatcg gctctagacc tttccagtcg tcagctgcca
     4261 gcggagtggt agtcacttca cgaccatccg gcatacggta agccacgcag agtttaacct
     4321 ctttcaggcc atccagaacg tccagtttag tcaggcagaa gccagacagg gagttcaact
     4381 gtaccgcacg acgaacggca acggtgtcca gccagccggt acgacgacga cgacccgtag
     4441 ttgcgccgaa ttcgttaccc tgcttgcaga ggaactcgcc agtttcatca aacagttcgg
     4501 tcgggaacgg acctgccccc acacgagtgg agtaagcttt gaggataccc agaacgtaat
     4561 caacataacg cgggcccagg ccggaaccgg tcgccacgcc accagcagtg gtgttggaag
     4621 aagttacgta cggatatgta ccgtggtcga tatccagcag cgtaccctgc gcaccttcaa
     4681 acatgacgaa atcgccacgc tgacgcgcct ggtcgagcag gtcagaaacg tcaacaacca
     4741 tagaagtcag gatgtcggca acagccatcg tatcatccag aactttctgg taatcaaccg
     4801 cttcagcttt gtagtagtta accaactgga agttgtgata ttccatcact tctttcagtt
     4861 tttcagcgaa ggtttctttg tcgaaaaggt cgccaacacg cagaccgcga cgtgctactt
     4921 tatcttcata agcaggcccg ataccacgac cggtggtgcc gatcgctttc gcgccacgcg
     4981 ctttctcacg cgcgttatcc agcgcaacgt gataatcaag gatcagcgga catgcttcgg
     5041 acagcagcag acgctcacga acggggatgc cacggtcttc cagttctttc atctctttca
     5101 tcagcgcagc cggagacagc acaacaccgt taccgatgat gctggttaca ttctcgcgga
     5161 gaatacctga tggaataaga tggagaacgg ttttttcacc gttgattacg agagtatggc
     5221 ctgcgttgtg accgccctgg tagcgtacaa catatttagc ccgttcagtc agaagatcga
     5281 cgatcttacc tttaccttcg tcaccccatt gggtgcccag tacgacgacg ttgttaccca
     5341 tttttcaaaa tcaccgtttg cttaaaaatg gattctacca tcgctttttc agagttacag
     5401 cactttttgc actcaaaaat gacctcgatc agtctgtttt ttgttcagcc aatcgttttc
     5461 ctcaacatgt agtagaccac aacgcccgca accacaagtc caccgccaaa acgacgtaaa
     5521 atattatcgg gcaaattggt catcgcagag atcatcttct tccatgcctt cgggtaaagc
     5581 atcggcccta aaccttccag taccaaaacc agggcaagcg ccagccagat tgtcgaattc
     5641 attcattatc cttatagaaa aagaaaacca ccgacatccc tgaggatgcg gtggctttat
     5701 tgacctgtac cgcagtcgtt atattaacgc gttgcggaag tcggcgtctt catgtagcgg
     5761 aagaaatcgc tgtccgggct catgaccatc acgtcctgat tgccagagaa gctgttctca
     5821 taagcacgca ggctacggat gaatgcgtag aagtccggat ctttactgaa tgcatcagca
     5881 aacagtttgg ctgcttctgc atcgccttca ccacgcatga tgcggccctg acgctcagct
     5941 tctgccagcg ttctggtcac ttcatagtcg gcagtcgcgc gcagtttttc cgcttcttcc
     6001 tgaccttgtg aacggtgacg acgtgctacc gcttcacgct cggcgcgcat acggttgtag
     6061 atcgcttcag acacttcggt cggcaggttg atctgcttaa ttcgcacatc gacaacttca
     6121 atacccagcg ccgccatact gttcgggttg atgaccggaa ctttgccctt cgtctcagcc
     6181 gttacgcgct ctgccgcttc ggcaatggcg ttatctgctg caggggtagt aacttcatct
     6241 tctgtacccg cagaaccgga gttcagcgcg tcacgtactt cgagggtcag acgaccacgg
     6301 gaatcggtga cgatatcttt cacgtccagg cgaccaattt cagaacgcag acggtcagag
     6361 aacttacgtt tcaacagcac ttccgcttgc gaaatgtcgc caccacccgt tgccagatag
     6421 taacggctga aatcgctgat gcgccatttg atgtaagagt cgacgatcag gtctttcttc
     6481 tctttggtca caaagcggtc ggcctggttg tccatggtct gaatacgtgc gtcgagcatt
     6541 ttcaccgttt caatgaacgg tatcttgaaa tgcagacccg gctcataaac cagaggtttg
     6601 ttgtcatcgt cacgcagtac cttaccaaaa cgcagcgtaa taccgcgctc accttctttg
     6661 acgacaaaga cagacatgta aagcactacc agcacgatga tgataatcgc gataactgac
     6721 ttacgcatcg ttattccccc tgacgctggt agtcgttacg ctgcgcgttg gcgcggcgtt
     6781 ggtccataat atcgccctga ctggtggacg acgtgttgct tgctccactg gttgtggagg
     6841 aagaggctgg cggcagacgc agcagattgc tggcaccgtt atcgctcttc gccgcagggg
     6901 cgttaccacc tttcagcatc tggtctaatg gcagaaccat caggttgcca cctttatcgt
     6961 taaccagcac tttgcgggtg ttgcccaaca ctttttccat cgtctcgata tacagacgct
     7021 cgcgagtaat ttccggcgcg gctttatatt ccggcagaag tttagcaaag cgcgccactt
     7081 caccctgagc ttccaggatg gtctgggcct tgtacgcacg cgcctcttcg aggatacgtt
     7141 gcgcctgacc gttcgcacgc ggctgaactt cgttggtata cgcttctgct tcacgaatgt
     7201 attgctgttc gttttcacgc gcggcaatcg catcgtcaaa cgccgctttt acttcttccg
     7261 gcggacgagc agcctggaag ttgacgtcca gcagcgtgat acccatgtca tacggacgaa
     7321 tcgtctcttc cagttcgcgc tgagtatcgc tacgaatcac ggtacgacct tccgtcagaa
     7381 tgcggtccat ggtgtattta ccgataaccc cgcgtagggc gctgtcggta gcctgacgca
     7441 ggctgtcatc cgggctggtc acgctataca gatatttttc cggatcggtg acgcggtact
     7501 gcacgttcat ctcaacgcgc actacgttct cgtccgacgt cagcatcaca ccagaagctg
     7561 ccagttcacg cacggcttcc acgttcaccg gtttgacttc gtcaataaac gtcggtttcc
     7621 agttcagacc cggctcaacc agatggctga atttaccaaa gcgtgttacc acgccgcgtt
     7681 cggcttcttt aatggtatag aaaccactgg ccgcccagat aatgacaatc gctgccgctg
     7741 cgatggtaac gacgcgaccg ccaagctgcg ggcgcgggcc ttgcgatgaa ctgccaccgc
     7801 cagatccggt gcctttaccg ccacccagac caccgagctt tttgctcagt ttgcggaaga
     7861 tatcatctaa atcaggtggc ccttgatcgc gaccgccttt gtttccattt ccctcagagt
     7921 tgccgccagg tttgctgctt ccccacgggt cgcggtcttg tccgttatta ccgggctgat
     7981 tccacgccat gtttgtgctc catatttgtt atgcggtgat ccctgttgtc tttcgacgcc
     8041 agaggatatg actccacgct tcagacgcta cgccgttaga tcaggtaatc gatcaacgcc
     8101 ggttcttgtt tacagaggcg acgccagtca acgatcggca tacgaacttg cagacttacg
     8161 ctgccgtcct cctccatcca ctctttttct attgcctgaa gctgataaaa acgacttctc
     8221 agacgccctt cctgcggcgg cagacgcaat gtatgctgcg ccacctcgcc ggaaagacgc
     8281 tccgtcaaag cctgaaaaag ctgtggtatc cccgctccgg tctgcgcaga aagccagaca
     8341 cggatcggtt tgttctcttc atctctgtca atacgcggtt cgaaatcgtc cagcatatcg
     8401 atcttgttca tcaccagcag ggttgggatc tcgtgagcat caatctcttc aagaaccgta
     8461 ttcaccgctt cgatgttttc ttgtacacgc acatccgccg cgtcaatgac gtgcagcagc
     8521 aatgtggctt gccgcgtctc ttgtaacgtg gctttaaatg ccgccaccag atcgtgcggc
     8581 aggtggcgaa taaaccctac ggtatctgcc aacacggttt caccgacatc cgcaacgtca
     8641 atacgccgca acgtcgggtc gagggtggca aacaactggt ctgccgcgta gacccgcgct
     8701 tcggtgatgc gattgaaaag ggtagattta ccggcgttgg tatatcccac cagcgaaaca
     8761 gtaggaacat cggctttgat acgcgattgc cgcccctgct cacgctgctt ttcaactctt
     8821 tccaggcgcg actgtatctg cacgatgcga ttacgcaaca aacgacggtc ggtttcgagc
     8881 tgggtttcac ccggaccacg caaaccgatc ccgcctttct gtctttcaag gtgggtccag
     8941 ccacgcacca ggcgcgtagc cagatggcgc aactgcgcca gctcaacctg caacttaccc
     9001 tcatgggtac gcgcacgttg ggcgaaaata tctaaaataa ggccggtgcg gtcgatgaca
     9061 cgacactcgc acaaacgctc caggttacgc tcttgcgccg ggctcagggc atggtcaaaa
     9121 agaacgaccg aagcacccgt cgcttttacg gcttccgcaa tttcaactgc tttaccttca
     9181 cctacaaaat actttgggtg cggcgcttta cggctaccgg taatcacctg caatgcttcg
     9241 acaccggcgg aagagaccag agattcaaac tcctggaggt cttccatatc tttgtcttgc
     9301 gtaaaataga tgtgtaccag taccgcctgc tcaccagcat cataacggtc aaacaagcgt
     9361 ataaccctct aaatagatca gcggggaacg caggatcgct ggctccccgt gtaaaaaaac
     9421 agcccgaaac cttattcggt ttcttcgctg tcctgttgcg cggaagtatt ctgcgcgctg
     9481 ctaccatgat gatagttact gctggtaccg ccaccggcgt tgttactgtg atgagaaacc
     9541 gggcgagacg ggacaacagt agaaatcgcg tgcttgtaaa ccatctggct gaccgtgttt
     9601 ttcaacagga tcacgaactg atcaaaagac tcgatttgtc cttgcagctt aataccattc
     9661 accaaataaa tagaaactgg aacacgttcc cgacgcagtg cgttcaggaa cggatcttgt
     9721 aaagattgcc ccttagccat tctctctttt ccttatatgc ttatttgtac tttgaacctt
     9781 tcgattctga aaaaattgcg cacgatacgt ctcaattgta cacattcagc ctgcgatagc
     9841 accaacaacc tgtaatactt cgtcacgcgc ctgttctggt ttttcactgt caagccagtg
     9901 aaccccttcc caaccacgca gccaggttat ctgccgcttc gccaactgtc tcgtggcgca
     9961 aacacctcga taaaccattt catcgtatga gatttcgcct tcaaggtaag accacatctg
    10021 gcgataaccc acgcaacgaa tggaaggcaa atccgtatgc aaatctcctc gggcaaaaag
    10081 cgcccggact tctgcttcaa aacctgaagc caacatctga tgaaaacgct gctcaattcg
    10141 ttgatggagc agttcacggc tcgccggggc gatggcgaac tgatgcacct gatacggtag
    10201 agcgtctcct gacgtttgcg tcagttccgt taaagtttta cccgaaatga aaaaaacttc
    10261 cagtgcccgg gaaagccttt gtggatcatt tggatgaatc cttgctgccg caaccggatc
    10321 tacctcctga agttgacgat gcaatgactc ccaaccttgc tctgccgcct gttgctcaat
    10381 tctggcccgt acttccgggt ccgccgacgg tagcggcgac aacccttcca gcaatgcctt
    10441 gaaatacaac atcgtaccgc ccactaatag tgggatccgc cccgccgcgg tgatatcggc
    10501 catttccgcc agcgcatcgc ggcgaaaatc agcagccgag taagcctgcg acggatcgcg
    10561 aatattcagc aatcggtgcg gcgcggcgag taactcttca gcgttcggct tcgccgtccc
    10621 gatatccatc cctttgtaaa taagggcaga atcaacgctt atcaactcta ctggtaaaat
    10681 tttacgcagc tcaatggcta acgctgtttt accggaggcc gtcggcccca tcaaaaaaat
    10741 cgccttaggc aggctcgcct tactgatatc actcatcttt cagggctttt atcgccggat
    10801 gtaaatcaac agattgtaac agaccacccg gcggcgtttt cacaagttgc ggacataacc
    10861 gttccacgtc cgccagcagg gttatggcct gtgccattga ccactgcgca tgttcgctca
    10921 tcagatttcg tgcaatccac tgcgcaatat tgccaggttc gaatacggac tgcttcgcca
    10981 ggtagcctat cagttcagga atcaagattt gtaaattttg ttggcgtaag ggtaaaggca
    11041 cggccctgat ggtcacatgc tgcgcatcgg actggaaatc aatacccaat tccgccaggg
    11101 cagactgcgc tttttctaat gccgattttt cttcgccaga aacttttagc cgcaacggaa
    11161 taagcagcgg ttgggcgcaa actggcactt cacccggcgt caattgtgcc tgacgcagcc
    11221 aacgttctgc cactggcaag gataaaagtg aaatgttgcc atcgcgctca agcaacgcac
    11281 agtcggaatg gacgatagtc agtacccgac caaaactctg actgttcgcc gcaagtgcag
    11341 gttcctgcgg ttctggcgct tttggttttt gcatcggcgc gggcgtttgc aaaagctggc
    11401 gatacacttc accttgctgt ttctggtaac ctggctgcgc attcggccag ggggcagccg
    11461 gacgactgcc tgaggagggc gcaggagtgt aacgcggagc tactggctca cgaactgccg
    11521 gttcagcaaa atgattgcgc cccgccgcca cgcgattttc cggaatggca cgcggtgcag
    11581 gttgtggttc atcgtccagc ggtagcggcg tttccagttg ctgttgtagc acgctcagca
    11641 cgccctgata gataaagtca tgcaccagac gcgactgatg gaaacgcact tcgtgtttgg
    11701 cagggtgcac gttgacgtcc acctgatgcg ggtcgatctc cagatacaac acaaatgccg
    11761 gttgctgatc ggcccccagt ttgtcttcgc aggcctggcg gatcgcgtga ttgatcaggc
    11821 gatcgcgcat catgcgaccg ttcacgtagc aatactgaat ttctgccagt gcgggcgtgg
    11881 tgtgatttgg atcggccacc cagccgcgca gcgtgagatc gccgtgttgc cattcaatcg
    11941 ccagcgcttg ttcgagaaaa gcggtgccgc aaatcgcgcc taagcgccgt tctttttgcc
    12001 cgccttccgg cactgcgcgg tactggcgta caattttgcc gttatgcgac aggttgatag
    12061 tgacgtcgaa acgcgccagc gcaatgcggc ggatgatttc atcgatatgg ttaaattcgg
    12121 ttttctcggt gcgcaggaat ttgcgccgcg ccggggtgtt gtagaacagg tccagcacct
    12181 ccagcgtcgt tcccaccgga tgcgccgccg gtttaaccgt cacgtccata ttgcgccctt
    12241 cggcataagc ctgccaggct tcctgctgtt ctgcggtgcg tgaagtgagc gtcaggcggg
    12301 aaaccgaact gatactcgcc agtgcctcac cgcgaaagcc caggctgata atggcttcga
    12361 gatcgtccag agaggcgatt ttactggtgg catgacgcgc cagcgccagt gccagctcat
    12421 cttttttgat accgcagccg ttatcacgaa tgcggataag tttcgcccca ccgcgttcga
    12481 tatcaatatc gatacgcgtc gcacctgcat cgaggctgtt ttccaccagt tctttgacta
    12541 ccgacgcagg tcgctcgacc acctcacctg cggcaatctg gttcgccagt tgtggcggta
    12601 agacctgaat tggcatcaat cgtccttagt ttggcagcgt gcgatctggc gtcgtcaccg
    12661 tactggccgt ttgtgccgtt gcaccctgcg gcgcagattg catcggatgc gcaaggaagt
    12721 aattgcgcag gcctttgtaa atggcttctg ccagctgttg ttggtaatcg tcgctcgcca
    12781 gcaaacgttc ttcgctgttg ttactgataa aaccggtttc gaccagtact gacggaatat
    12841 ccggcgaacg cagaacgccg agactcgcgt gttctggtcg gcgtttatgt atttcgccaa
    12901 tgcgttgcaa ctgactgatc atactggtcg ctacatcata ccctacccgc tgggaatgac
    12961 cgaactgtaa atccagcacc gcctggctta aataggggtc ggcctgactg ttcgccagca
    13021 catcacccgc cccgcccagc agctccgact gcttctcatg ctgttccagc cagctggcca
    13081 tttcgctgtt ggcgcgacgg tttgagagca cccatacaga ggcaccggtg gcactacggt
    13141 ttggtgcggc atcggcatga atcgacacaa ggaaattggc gttttgctta cgtgccacat
    13201 cactgcgccc catcaccgag ataaagtaat ccccgtcacg ggttaaaacg cccttaaaca
    13261 tcggatcgtt attgagcaag gtacgtaatt tacgcgcaat ggcgatggtg acatttttct
    13321 cccgtgtacc accagggccg atagcgccag ggtcctgacc gccgtgtccg gcatcaatag
    13381 cgatgataat tttatcgcct gtgttagccg tcgcgcgcgc tgccggacgc gttaccgtat
    13441 tactgctgat aacacccgta gtgcggttac tttccgtttt aaacggattg cgcgccggtt
    13501 cgctgacgcg cggtgcgaca accgcaggcg tttcaacgcg tttcgcaacc attggcggag
    13561 gcgatggcgg cgcatcggcg ttaatcgtaa agacaacagt gtaattgctg ccattctgcc
    13621 gcttcaccgc ttcggtttta ccgttttcgg tgagatcgac caccagccgt agcgtttgtg
    13681 catctttagg cgttccggag cgaatcgctt tcaccaggtt attaccgcta aacaacaacg
    13741 gcagcccctg aattaccccc gtttgtttga tatcgagcgc cacggtgcgt ttgctttgat
    13801 ggctaaacgc ataatcagga tcgccaataa aactcaacgt tatccgcgcc tgttgattac
    13861 cgttagaaac ctgaatatca gagagcgtcg cggcccccgc ctgcgcgcac agcagcagca
    13921 acgtcgctac taaccaattt ctgatgcgat acatcatccc gccacctttc aaaggttaac
    13981 cggctaaacg cgccagcaac aattcacccg cagaggaaac cgcactcacg cgcgcctcac
    14041 ggccttgtgc ctgataatca atgtgtattt cgacatccgg gtcaggaaga acacctgtac
    14101 cttgttgtgg ccactccacc aggcagatgg catcgttggc aaaataatcg cggatcccca
    14161 taaactccag ctcctcggga tcggcaaggc ggtacaaatc aaagtgataa accattaaat
    14221 tgtcgagcgt atagggttcg accagcgtat aagtggggct tttgacatta ccctgatgac
    14281 ccagagcctg taaaaagccc cggctaaagg tggttttacc tgcgcctaaa tcgccataca
    14341 gatagattac ggttgcgcca tcgcaggctt tcgctacccg ctcgcccagg tctaatgttg
    14401 cctgctcatc agggagcgga attactcgat tcatcatggt ttttatcagt cacttccggg
    14461 ttaacaatac gctgtagcgt ggaaaagaga tcggttgcca gcatcccgcg cgttccaaaa
    14521 cgcgccgcca gtacgtcagc tgccgcaccg tgcgcgacac agcccgcaca ggctgcatca
    14581 taagggctca ttttttgccc aagcaatgcg ccaataatac cagagagcac atcgcccatg
    14641 ccgccgctcg ccatgcctgc atttccggca tcaataatgc ctaaagcgtc aggatgggcg
    14701 gcgaccacgg ttccggcacc tttcagcacc gctacgccgc cataacgttg taccagacgt
    14761 tgggcgcaat gtaagcggtc actttcaatt tcagcgacgg aacatcctaa caaccgtgcg
    14821 gcctcaccag gatgcggcgt gatcacgcga ttgtgacgct tatcgggatt gattgccagc
    14881 aggttcaatg catcggcatc ccacaacatc ggtttgcgaa aattctcaac tttttgcagg
    14941 gcttttttcc cccactcttg ctggcccaga ccgggaccaa tcaccaccac atcggcccat
    15001 tccaggcttt cggtaagaga gcccatagtc agttcatgca ccatcaattc cggtcgtgca
    15061 gtcagcagcg gcgcaatgtt ctcactgcgg gtcagtactc ggactaaacc agcaccagca
    15121 cgcagcgccg cttcccccgt catacgaata gcccccgccg tgccgtgatc gccaccaata
    15181 atcaccagcc gcccgtgatc gcctttatgc gaagtcgggc gacgcggtat cagccactga
    15241 gaaagttgtt ctgccgaaaa ccgctgaatt ttcgtctcct gacctgccag ccatctatcc
    15301 agccgcagtg agtcaaaatg cagttgtccg gtaacatccc gcgcttttcc agtgagcaaa
    15361 cctggtttca gcgcaataaa agtgatggtg tgatcggcgt tgattaccgc gcctggcgta
    15421 gcgccggttt cagccagaag gccggaaggg atatcaaccg ccacaatcgg cgcaggatgg
    15481 gaattagcgt ggtcgattaa ctggctaatg gattcgcggg gcgcttgctg caaaccggtg
    15541 ccgagcagcg catcgacaat cagatctacc gattcgggcc agacaatatt cgaagcatgg
    15601 atctcgcctc ccgcgtttaa ccatgcttcg cgtgccagcg cggcctcttc cggcaacggt
    15661 ttgtcacttt cctgggccag cagcgtgaca tcaataccga tcgctttggc cagccgcgcg
    15721 accacgtagc catcgccgcc gttattacca tgaccgcaca gcaccagcca gtggcgggcg
    15781 tcaggataag ccgaacgaca cacctggaat gcggcttcgc cagcgcgaag catcagctca
    15841 tagagtgtga gccccagcgc atctgccgcc tcgcgttctc cgcggcggat atcgtcggcg
    15901 taccagacgg tgtgtggtat acttacgggg tttttcttca ttgtatggtc cgtcatgtca
    15961 gagcccctcg atctcaatca gttagcgcaa aaaattaaac agtgggggct ggaactgggc
    16021 tttcagcagg taggtattac cgataccgat ctcagcgagt ccgagcccaa actgcaagca
    16081 tggctggaca aacaatacca cggcgaaatg gactggatgg cgcgtcacgg tatgctgcgt
    16141 gctcgtcctc acgaattatt gcccggtacg ctgcgcgtga tcagcgtgcg gatgaattac
    16201 cttcctgcta acgccgcatt tgccagcacg ctgaaaaatc ccaaactcgg ctatgttagc
    16261 cgttatgcgc tgggccgtga ctatcacaag cttctgcgca accgactcaa aaagctgggc
    16321 gagatgattc agcaacattg tgtttcgctg aattttagac cgtttgtcga ttctgcgcct
    16381 attctcgagc gcccgttagc tgaaaaagca ggtcttggct ggacaggtaa gcactcactt
    16441 atcctcaatc gcgaggccgg ttcgttcttc tttttaggcg aattgctggt cgatattccg
    16501 ctgcccgtgg atcaaccagt cgaggaagga tgcggtaaat gcgtggcctg tatgacgatt
    16561 tgcccgaccg gtgccatcgt cgagccatat accgtcgatg ctcgccgctg tatctcttat
    16621 ctcaccatcg aactggaagg ggagatcccg gaagagttgc gaccgttaat gggaaaccgt
    16681 atttacggtt gcgatgactg ccagcttatc tgcccgtgga atcgctattc gcaactcact
    16741 acagaagacg atttcagccc gcgtaagccg ctacacgcac cggaactcat tgagttattc
    16801 gcctggagtg aagagaagtt tttaaaagtc acggaaggtt cggcgattcg ccgtataggt
    16861 cacctgcgtt ggctgcgtaa tatcgccgta gcattaggca atgccccctg ggatgaaacg
    16921 attttgacag cgctggaaag tcgtaaaggt gagcacccac ttcttgatga gcacatagcg
    16981 tgggcgattg cgcagcaaat cgagagacga aatgcgtgcg tggtcgaagt gcaattaccg
    17041 aaaaaacagc gtctggttcg ggtgattgaa aaagggttac cgcgtgacgc ctgattcatc
    17101 cacagcttgt gaataaaaat aaaaacgcat tgcaattcaa gccggaaaaa atcgtcaagt
    17161 gatcgatacg acaaaacgaa atcttaattt ttaacttatc tatcaatagg ttaaaaaaat
    17221 actattcacc gtgcgaagtt tctttgaaat taagattacg gcctgaggct gtggataact
    17281 ctgtttacaa gagtttgtca gagacaacaa aaaccagcaa taacgcatcg cgtcgctgtg
    17341 gatattttat tgagagaaga atttggagcg ggaaacgaga ctcgaactcg cgaccccgac
    17401 cttggcaagg tcgtgctcta ccaactga
//
LOCUS       DAFGPF010000104        17221 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFGPF010000104 DAFGPF010000000
VERSION     DAFGPF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17221
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.104"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            261..539
                     /locus_tag="LSX49_003871"
                     /pseudo
     CDS             261..539
                     /locus_tag="LSX49_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(590..835)
                     /locus_tag="LSX49_003872"
                     /pseudo
     CDS             complement(590..835)
                     /locus_tag="LSX49_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            complement(1208..1438)
                     /locus_tag="LSX49_003873"
                     /pseudo
     CDS             complement(1208..1438)
                     /locus_tag="LSX49_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546148.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            2025..2180
                     /locus_tag="LSX49_003874"
                     /pseudo
     CDS             2025..2180
                     /locus_tag="LSX49_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608786.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
     gene            complement(2177..2623)
                     /locus_tag="LSX49_003875"
                     /pseudo
     CDS             complement(2177..2623)
                     /locus_tag="LSX49_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001218945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
     gene            complement(2810..2894)
                     /locus_tag="LSX49_003876"
     tRNA            complement(2810..2894)
                     /locus_tag="LSX49_003876"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2858..2860),aa:Leu,seq:caa)
     gene            3090..4109
                     /gene="ahr"
                     /locus_tag="LSX49_003877"
     CDS             3090..4109
                     /gene="ahr"
                     /locus_tag="LSX49_003877"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HBL7170226.1"
                     /translation="MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVI
                     LKADF"
     gene            4239..5741
                     /locus_tag="LSX49_003878"
     CDS             4239..5741
                     /locus_tag="LSX49_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HBL7170227.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIGVNDWQPHANPVVVWDIFG
                     EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLDIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRTFTPKDQKAV
                     KAAAQTMRVNPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPMTE
                     DERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASAEQQNNPAVKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR"
     gene            complement(5902..6984)
                     /gene="lptG"
                     /locus_tag="LSX49_003879"
     CDS             complement(5902..6984)
                     /gene="lptG"
                     /locus_tag="LSX49_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HBL7170228.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQIDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(6984..8084)
                     /gene="lptF"
                     /locus_tag="LSX49_003880"
     CDS             complement(6984..8084)
                     /gene="lptF"
                     /locus_tag="LSX49_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HBL7170229.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            8351..9862
                     /gene="pepA"
                     /locus_tag="LSX49_003881"
     CDS             8351..9862
                     /gene="pepA"
                     /locus_tag="LSX49_003881"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBL7170230.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            10218..10661
                     /gene="holC"
                     /locus_tag="LSX49_003882"
     CDS             10218..10661
                     /gene="holC"
                     /locus_tag="LSX49_003882"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HBL7170231.1"
                     /translation="MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            10661..13516
                     /gene="valS"
                     /locus_tag="LSX49_003883"
     CDS             10661..13516
                     /gene="valS"
                     /locus_tag="LSX49_003883"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBL7170232.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(13570..14766)
                     /locus_tag="LSX49_003884"
     CDS             complement(13570..14766)
                     /locus_tag="LSX49_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709944.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 domain-containing protein"
                     /protein_id="HBL7170233.1"
                     /translation="MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLP
                     WALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFFYFAILMTVSADMPLVDCV
                     LTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSLKGFWWVTFFLPILMAIGMGTV
                     FFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFK
                     VKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQ
                     RKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCAL
                     VVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIM
                     PSLPFL"
     gene            14959..15462
                     /locus_tag="LSX49_003885"
     CDS             14959..15462
                     /locus_tag="LSX49_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL7170234.1"
                     /translation="MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGK
                     GLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCE
                     VRMLREL"
     gene            complement(15508..15924)
                     /gene="rraB"
                     /locus_tag="LSX49_003886"
     CDS             complement(15508..15924)
                     /gene="rraB"
                     /locus_tag="LSX49_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HBL7170235.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH"
     gene            16086..17090
                     /gene="argF"
                     /locus_tag="LSX49_003887"
     CDS             16086..17090
                     /gene="argF"
                     /locus_tag="LSX49_003887"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL7170236.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNTLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKTFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNNKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
                     "
BASE COUNT         4368 a         4362 c         4460 g         4031 t
ORIGIN      
        1 tattttattg atggtagcta acttagtaat tatataaaaa acttttacaa tatccgagag
       61 tatgtatgca taatgtatgc gcccccctat caggctgtct cttatacaca aatccccacc
      121 cggggatttg tgatgtctgt cagtctgctt taggggggac tctttccatt cggtagtttc
      181 cttcctcccc ggcagcgatt ttttgaactt tttcttcacc cgttgatctt ctcttatatt
      241 tcattttctt cgggtctgtt atggtacttt ctgattgtta ttcatgggat aacgagcagt
      301 ttggacatgc ccgtctcggt gatccgcgtc gtacacgacg ccttgtgtca ctggcctctt
      361 ctctcgctca gcatgcaggt ctttctattg tgaaatcatc ccactccact gctcaggttg
      421 aaagtgcgta ccgcctgata cgtaacccgt ctgtgtcccc ggaagccatt gcctaagccg
      481 gatttaccgc cactgcaagg gcatgtgagg ctcatccgct gctcctcgca ctggaagaca
      541 ccaccactaa tcgtaagcgt acagcgaggg ccgtattgac ggggatgtgt tattcagctg
      601 gcagtgctat acgccacgga agcagttcgc tgacccggtt gaccggccag tctgctatga
      661 cgccaagcac atggcgaagg tagctttctg gatccacgtc attcagtttg cacgtcccga
      721 tcaggctgta cagtagcgct ccccgctcac caccatggtc agagccgaag aacaggaagt
      781 ttttacgacc cagactgacc gtcaacgcca caatctttga ctgtttgaca ttgtcatgcc
      841 cgcaggccag cgaatctaaa gacatcagac tgcttgcatc agccagttgc gtatctggct
      901 atgtccctta attggtaagg gttcgaggaa ctcaacatta acgcattttt ccgcccatca
      961 ccggcagtgt atatgaacga ttgcactctt acgatggttg atttatttgg ttgcgtaggg
     1021 gctagctagt ctggtaccgg aggctggatc tgaagtactg accccaagaa taacgccggg
     1081 cagactcata ttctgaccca ttgtcagccc gcgtgtttac tgctctagct catttcctgt
     1141 tgtcaggcgt tcaattccca actgcaggtt atggcccggt gcacaaacac ctgacggcag
     1201 gtatcactta cccaaagaag ataaagccct caagaggcag taactctgcc aacctctcct
     1261 ccggccactc cgggcagacg cgttaggacg tccgtcagcc aagcatgtgg ctccagactg
     1321 ctgtttccag aaggctcatt atctgtgccg ctcggttccc ggccatcagt gaaccagcga
     1381 acaaccaggc ctttcgtccc ataacgaccg gacggatagc acgctcgcag atattgttgt
     1441 gtgtgccttg aaatgcacga tctttccgtc ggtgaaagtc cgccccgact aactctcgct
     1501 ccaactggaa ggacaggaag cggtccagga ggtaacaaaa gggctgaatc tctccctgaa
     1561 acgacttctt caggaagtca atgggttatg cgggccgtaa cgtgagtgaa cactgagcag
     1621 ccatcgaaat gccgtcgatg gtgccgatac gccacaataa cggggaaggc cgacgatgac
     1681 cgggaagaga gtgagaaagg catcggtcat acccaccggg gtagtggtgt cagcatgcat
     1741 aacaattgat cgatcgtgca acaagagaag tccataacga tgcctgtccg ggtgacgggc
     1801 aacaacgcct cccgaggggg tgaatcggtt gttatggatg gcagatgggg tgtagtagtg
     1861 aaaatactga gtaatgtcat aggagcgaag gccccctgtt gcagtaccag tgtaacatgc
     1921 aggaagagcc cggggattgc catcagcctc acaaccccgc tcgaaccggt tcagaaccta
     1981 cagaaaatac tacaggagaa agcaaagtga acctccccgt gtttcctgtt tatcattttc
     2041 tggtcagtgc cgcgattctg gtattcgtgg tgattttctg gcggacacac catcgcgacc
     2101 accgtaactg gctggctcta cggctattcg tattatgctc tgtaaaccgt tggccattgc
     2161 ggatggttaa aggaacaata ggtgctaata aatctcgagt ttttaactca gcgatattac
     2221 gttcaccaag cgctgcaaaa agattatctt caagactttt tagcacacga tgggcgtgat
     2281 cttcagacca ctttttattg gtgccatgcc actcaatcgc gacttcttta aaggttcgtg
     2341 ctttactctg ttcaacctta tcatttttct ttttgtctcc cggatcgacg ccattcgcaa
     2401 gcagcttacg cgcctcgtca cgacgtactc tggcatccgc tagtgtgatt tcaggataaa
     2461 ccccaagtgc cagcattttt tgctttccct cataacggta ctgcaaacgc cagtacttag
     2521 aaccatttgg atggacaagc agatgcatac cgccaccatc agtcagctta tattgcttat
     2581 ccgttggctt ggctgctctg actttgatat ctgttaatgc catgcgtatt ccctccctgt
     2641 tggtacaagc attatcgaac cggaaatacc atcatctgta ccaacatatg ttggtagatg
     2701 tacgttgata tcggttgacc ttgagagagt taatatagcg ggaaagatag ataaacactg
     2761 gatttcaggc ataaaaaaag acctcagttg aggtctattt acatactttt ggtgccgaag
     2821 gccggactcg aaccggcacg tatttctacg gttgattttg aatcaactgc gtctaccgat
     2881 ttcgccactt cggcactgaa gaggtatgcg gaaaacgttg tggattatac ctgtcgcacg
     2941 ccaccatgca agcgccagct tgctcgcacc tcgctaagtg ctgaaatttt cagcattgca
     3001 tacagcgatg tgtaaccttt gtcacactcc aggcaccccg ccctgccatg ctctacactt
     3061 cccagacaac accagagaag gaccaaaaaa tgtcgatgat aaaaagctat gccgcaaaag
     3121 aagcaggcgg cgaactggaa gtttatgagt acgatcccgg tgaactgaag ccacaagatg
     3181 ttgaagtgca ggtggattac tgcgggatct gccattccga tctgtcgatg atcgataacg
     3241 aatggggatt ttcacaatat ccgctggttg ccgggcatga ggtgattggt cgcgtggtgg
     3301 cgctcgggag cgccgcgcag gataaaggtt tgcaggtcgg tcagcgtgtc gggattggct
     3361 ggacggcgcg tagctgcggg cattgcgatg cctgtattag cggtaatcag atcaactgtg
     3421 agcaaggtgc ggtgccgacg attatgaatc gcggtggctt tgccgagaag ttgcgtgcgg
     3481 actggcaatg ggtgattcca ctgccagaaa atattgatat cgagtccgcc gggccgctgt
     3541 tgtgcggtgg tatcacggtc ttcaaaccac tgttaatgca ccatatcact gccaccagcc
     3601 gcgttggggt aattggtatt ggcgggctgg ggcatatcgc tataaaactt ctgcacgcaa
     3661 tgggatgcga ggtgacagcc tttagttcga atccggcgaa agagcaggaa gtactggcga
     3721 tgggtgccga taaagtggtg aatagccgcg atccgcaggc actgaaagca ctggcggggc
     3781 agtttgatct cattatcaac accgtcaacg tcagcctcga ctggcagcct tattttgaag
     3841 cgctgacgta cggcggtaat ttccatacgg tcggtgcggt tctcacgccg ctgtctgttc
     3901 cggcctttac gttaattgcg ggcgaccgca gcgtctctgg ttctgctacc ggcacgcctt
     3961 atgagttgcg taagctgatg cgctttgccg cccgcagcaa ggttgcgccg actaccgaat
     4021 tgttcccgat gtcgaaaatt aacgacgcca ttcagcatgt acgcgatggt aaagcgcgct
     4081 accgagtgat cctgaaagcc gacttctgat ccctttgccg ggtgcctgtc gcccggcact
     4141 taaatctctt tggaaggcgt ctcgcaatct gctgaattta gcggtgaaga gtgcgcagcc
     4201 gttgcctata ctccaggcag gaaactggag gaaatctcat gagcgaaccc ctgttaattg
     4261 cccgcacgcc ggacacagaa ctatttttac tgccgggaat ggctaaccgt cacgggctga
     4321 ttactggcgc aacggggacg ggtaaaactg tcacgctgca aaaactggcg gagtctctat
     4381 cggaaatcgg tgttccggtg tttatggccg atgtgaaagg cgatctgacc ggcatcgcgc
     4441 aggcaggaac ggcgtcggaa aaactgctcg caaggcttaa aaatatcggc gtcaatgact
     4501 ggcaaccgca tgccaatccg gtggtggtgt gggatatctt tggcgagaaa ggccatccgg
     4561 tgcgggcgac ggtttcggat ctggggccgc tgttgttggc gcggctgttg aatctcaacg
     4621 atgtgcagtc tggcgtgctg gatatcatct tccgcattgc tgacgatcag gggctgttac
     4681 tgctcgactt taaagatttg cgggcgatta cccagtacat cggcgataac gccaaatctt
     4741 tccagaatca gtacggaaat atcagtagcg catcggttgg tgccatccag cgcgggctgt
     4801 tgtcgctgga acagcaaggc gcagcacact tctttggtga gccgatgctg gatatcaaag
     4861 actggatgcg caccgatgcc aacggtaaag gcgttatcaa tatcctcagc gccgagaagc
     4921 tttatcagat gccgaaactg tatgccgcca gcctgttgtg gatgctctcg gagttgtatg
     4981 aacaattgcc ggaagcgggc gatctggaga aaccaaaact ggtgtttttc ttcgacgagg
     5041 cacatctgct gtttaacgat gcaccgcagg tactgctgga taagattgag caggtgataa
     5101 ggcttattcg ctcaaaaggc gtgggcgtct ggttcgtttc gcaaaatccg tccgatattc
     5161 cggataacgt gctcggccag ctcggtaatc gcgttcaaca cgctttgcgg acttttacgc
     5221 ccaaagatca gaaagcggta aaagctgcgg cgcaaaccat gcgggtcaat ccggcatttg
     5281 ataccgaaaa ggcgattcag gaactgggca ccggcgaggc gttgatctct tttctggatg
     5341 cgaaaggaag cccttctgtg gtggaacggg cgatggtgat tgcgccttgt tcgcggatgg
     5401 gaccgatgac ggaagatgag cgtaatggct tgattaatca ctctccggtg tatggcaagt
     5461 acgaggatga cgtggaccgg gaatccgcct atgagatgtt gcaaaaaggc gtacaggcaa
     5521 gcgccgagca gcaaaataat cctgccgtga aagggaaaga ggtggcggtg gatgacggca
     5581 ttcttggtgg attgaaggat attttgtttg gcactaccgg accacgcggc gggaagaaag
     5641 atggtgtggt gcaaacaatg gcgaaaagcg ccgcccgcca ggtgacgaat cagattgtac
     5701 gtgggatgtt ggggagtttg ctggggggaa gaagaaggta agtcaggcgc gatttgtctt
     5761 tgcctgatgc gacgctggcg cgtcttatca tgcctacacc actgcaatat attggatttt
     5821 catgattttt caggcatgaa cgaagcacac tttgctaaca ataataaagg gagctttcgc
     5881 tccctttatt cgttcattcg gttacgattt tctcattaac agccacaggc tgattaagaa
     5941 gaagctggcg cttggcaaca gtgcgccgat gatcggcggg atgccataaa ccaacgtcag
     6001 cgggccgaag atctggtcca gtacatagaa gacaaaaccg aagctgatac cggtgaccac
     6061 acgcacaccc atcggtacgc tacgcagtgg gccaaagatg aacgacagcg ccatcagcat
     6121 catcaccgcc acggatagcg gctggaagat tttgctccac atgttgagct gataacgtcc
     6181 ggcatcctga ccgctcgatt tcagatactt cacatagttg tgcaaaccgc tgatagagag
     6241 tgcatccgga tccagcgcca ccacgcccag tttgtcaggc gtgaggttgg ttttccaggt
     6301 gccgctcacc gtctgcgaac cggtgatctg tttcggattg gtcagatcag attcatcaat
     6361 ctgcgacaga cgccagactt tatgttccgg gtcaaacttc gcggtagcgg catagcgtac
     6421 ggattgcaga cgacgattct cgttaaaggc ataaatactg atgccaccta actcttcgtc
     6481 acctttaacc cgctcaatgt agacgaagtt gttgccatct ttcgcccata aaccttgctg
     6541 ggtagagagc aacgagccgc cgtacatcgc ctgcgcacgg tagttacgcg ccatctgctc
     6601 gccctgcggc gcgacccatt cgccaatcgc catcgtcagc aagaccagcg gaatggcggt
     6661 tttcatcacc gacagcgcca cctgcatacg ggtaaaacca gaagcctgca tcaccaccag
     6721 ttcgctgcgc tgcgccagca tcccaagacc aagcaacgcc ccaagcaaag ccgccatcgg
     6781 gaagaatatt tgcacatctt tcggcacgct cagcaaggta tacattcctg cgcctaacgc
     6841 gtcgtagctc ccctgcccgg cttttttcaa ctgatcgaca aatttgataa tgcccgacag
     6901 cgacaccagc atgaacagcg tcatcatgat ggtggtgaaa atagttttac cgatatagcg
     6961 gtcaagtacg ccaaaaggtt gcatcacacc gctcctttac gcgaaaaact ggcgcgcagg
     7021 cggcggaccg gcacagtgtc ccaaaggttg agaacaatcg ccaaagccag ataaatcagg
     7081 ttaacggtcc acatccacag cgtcgggtcc agcttacctt taccgccgtt cgatttcagg
     7141 gaggtctgga tcaggaagaa aagtagatac agcagcatgg ctggcagcat cgacagtacg
     7201 cgtccctgac gcgggttaac cacgctcaac ggtacaacca taagtgccat cataaacacg
     7261 gtgaatacca acgtgatacg ccagttcagt tctgcgcggg cacgatcggt gtcagtgttc
     7321 cacaatgtgc gcatgtccat ctggtcggta tcgttcgggt cgagcgccac cgcctggtga
     7381 ccaatgatcg cctgataatc ctggaaatcc gtaatgcgga aatcacgtaa cagtgcagtg
     7441 ccttcgaagc gcgttccctg gttgagagtg acgacctggg agccgtcgcg cagctgggtt
     7501 aaatgtccgg aatcggccac caccacagaa ggtcgtgcat taccttttgg tcgaatttgt
     7561 gcgaggaaca catctttgaa atcgctgccg tcaacgcttt cgatgaacag caccgagctg
     7621 ccattagtcg cttgctggaa ttgcccttgc gccagcgccg ccatgccagg gttcgctttc
     7681 gcttctgcta acacttcatc ctgatgacgc gatgaccacg gtcccgccca catcacgtta
     7741 accgccgcga cgattgccgt gaataccgca aggatcattg ccgctttcac cagaaccgct
     7801 ttgctcaggc cgcaggcatg cattaccgta atttcacttt cggtatacag tttgcccagc
     7861 gtcatcagca gcccgaggaa caggcttaat ggcaggataa gctgcgccat ttccggcacg
     7921 cccaacccga gaagggagag caccagattc gccggaatat cgccgtcaac cgctgcgccg
     7981 aggatcctca ctaacttttg acagaagaag atcaaaagca agatgaagag tatcgccagc
     8041 tggcttttga gcgtctcccg caccagatat cttatgatta tcactttaaa tacgcccgta
     8101 aaaactcgtc ttttgcagga ttttagcttg tttcatggct taaacgtcat ttattctctt
     8161 gagtcgtcga aatcgtcgct aagataatta tactcaacgg attcacctct cagattttgt
     8221 tctgacgtgc caatgccgta ataacgttaa gattaacacg aagtcatcgc aacagcggac
     8281 atgagttacg aaagcttgca attctatctg tagccaccgc cgttgtcttt aagattcagg
     8341 agcgtagtgc atggagttta gtgtaaaaag cggtagcccg gagaaacagc ggagtgcctg
     8401 catcgtcgtg ggcgtcttcg aaccacgtcg cctttctccg attgcagaac agctcgataa
     8461 aatcagcgat gggtacatca gcgccctgct acgtcggggc gaactggaag gaaaaccggg
     8521 gcagacattg ttgctgcacc atgtaccaaa cgtgctttct gaacgcatcc tccttattgg
     8581 ttgcggcaaa gaacgtgagc tggatgagcg tcagtacaag caggttattc agaaaaccat
     8641 taatacgctg aatgatactg gctcaatgga agcggtctgc tttctgactg aactgcacgt
     8701 taaaggccgt aacaactact ggaaagtgcg tcaggctgtc gagacggcaa aagagacgct
     8761 ctacagtttc gatcagctga aaacgaacaa gagcgaaccg cgtcgtccgc tgcgtaaaat
     8821 ggtgttcaac gtgccgaccc gccgtgaact gaccagcggt gagcgcgcga tccagcacgg
     8881 tctggcgatt gccgccggga ttaaagcagc aaaggatctt ggcaatatgc cgccgaatat
     8941 ctgtaacgcc gcttacctcg cttcacaagc gcgccagctg gctgacagct acagcaagaa
     9001 tgttatcacc cgcgttatcg gcgaacagca gatgaaagag ctggggatgc attcctatct
     9061 ggcggtcggt cagggttcgc aaaacgaatc gctgatgtcg gtgattgagt acaaaggcaa
     9121 cgcgtcggaa gatgcacgcc caatcgtgct ggtgggtaaa ggtttaacct tcgactccgg
     9181 cggtatctcg atcaagcctt cagaaggcat ggatgagatg aagtacgata tgtgcggtgc
     9241 ggcagcggtt tacggtgtga tgcgtatggt cgcggagcta caactgccga ttaacgttat
     9301 cggcgtgttg gcaggctgcg aaaacatgcc tggcggacga gcctatcgtc cgggcgatgt
     9361 gttaaccacc atgtccggcc aaaccgttga agtgctgaat actgacgctg aaggccgcct
     9421 ggtactgtgc gacgtgttaa cttacgttga gcgttttgag ccggaagcgg tgattgacgt
     9481 ggcgacgctg accggtgcct gcgtgatcgc gctgggtcat catattactg gtctgatggc
     9541 gaaccataat ccgctggccc atgaactgat tgccgcgtct gaacaatccg gtgaccgcgc
     9601 atggcgctta ccgctgggtg acgagtatca ggaacaactg gagtccaatt ttgccgatat
     9661 ggcgaacatt ggcggtcgtc ctggtggggc gattaccgca ggttgcttcc tgtcacgctt
     9721 tacccgtaag tacaactggg cgcacctgga tatcgccggt accgcctggc gttctggtaa
     9781 agcaaaaggc gcaaccggtc gcccggtggc gttgctggca cagttcctgt taaaccgcgc
     9841 tgggtttaac ggcgaagagt aattgcgtca ggcaaggctg ttattgccgg atgcggcgtg
     9901 aacgccttat ccgacctaca cagcactgaa ctcgtaggcc tgataagacg cgcaagcgtc
     9961 gcatcaggca atgctgttat tgtcggatgc ggcatgaacg ccttatccga cctacacaca
    10021 gcactgaact cgtaggcctg ataagacaca acagcgtcgc atcaggcaat gctgttattg
    10081 tcggatgcgg cgtgagcgcc ttatccgacc tacacacagc actgaactcg taggcctgat
    10141 aagacacaac agcgtcgcat caggcgctgc ggtgtatacc tgatgcgtat ttaaatccac
    10201 cacaagaagc cccatttatg aaaaacgcga cgttctacct tctggacaat gacaccaccg
    10261 tcgatggctt aagcgccgtt gagcaactgg tgtgtgaaat tgccgcagaa cgttggcgca
    10321 gcggtaagcg cgtgctcatc gcctgtgaag atgaaaagca ggcttaccgg ctggatgaag
    10381 ccctgtgggc gcgtccggca gaaagctttg ttccgcataa tttagcggga gaaggaccgc
    10441 gcggcggtgc gccggtggag atcgcctggc cgcaaaaacg cagcagcagc ccgcgcgata
    10501 tattgattag tctgcgaaca agctttgcag attttgccac cgctttcaca gaagtggtag
    10561 acttcgttcc ttatgaagat tctctgaaac aactggcgcg cgaacgctat aaagcctacc
    10621 gcgtggctgg tttcaacctg aatacggcaa cctggaaata atggaaaaga catataaccc
    10681 acaagatatc gaacagccgc tttacgagca ctgggaaaag cagggctact ttaagcctaa
    10741 tggcgatgaa agccaggaaa gtttctgcat catgatcccg ccgccgaacg tcaccggcag
    10801 tttgcatatg ggtcacgcct tccagcaaac catcatggat accatgatcc gctatcagcg
    10861 catgcagggc aaaaacaccc tgtggcaggt cggtactgac cacgccggga tcgctaccca
    10921 gatggtcgtt gagcgcaaga ttgccgcaga agaaggtaaa acccgtcacg actacggccg
    10981 cgaagctttc atcgacaaaa tctgggaatg gaaagcggaa tccggcggca cgattacccg
    11041 tcagatgcgc cgtctcggca actccgtcga ctgggagcgt gaacgcttca cgatggacga
    11101 aggcctgtcc aatgcggtga aagaagtttt cgttcgtctg tataaagaag acctgattta
    11161 ccgtggcaaa cgcctggtaa actgggatcc gaaactgcgc accgctatct ctgacctgga
    11221 agtggaaaac cgcgaatcga aaggttcgat gtggcacatc cgctatccgc tggctgacgg
    11281 cgcgaaaacc gcagacggta aagattatct ggtggttgcg actacccgtc cggaaaccct
    11341 gttgggcgat accggcgtgg ccgttaaccc ggaagatccg cgttacaaag acctgattgg
    11401 caaatatgtc attctaccgc tggttaaccg tcgtattccg atcgttggcg acgaacacgc
    11461 cgacatggaa aaaggcaccg gctgcgtgaa aatcactccg gcgcacgact ttaacgacta
    11521 tgaagtgggt aaacgtcacg cgctgccgat gatcaacatc ctgacctttg acggcgatat
    11581 ccgtgaaagc gcccaggtgt tcgataccaa aggtaacgaa tctgacgttt attccagcga
    11641 aatcccggca gagttccaga aactcgagcg ttttgctgca cgtaaagcag tcgttgctgc
    11701 ggttgacgca ctcggcctgc tggaagaaat taaaccgcac gacctgaccg ttccttacgg
    11761 cgaccgtggc ggcgtagtta tcgaaccaat gctgaccgac cagtggtacg tgcgtgccga
    11821 tgtactggcg aaaccggcgg ttgaagcggt tgagaacggc gacattcagt tcgtaccgaa
    11881 gcagtacgaa aacatgtact tctcctggat gcgcgatatt caggactggt gtatctctcg
    11941 tcagctgtgg tggggtcacc gtatccctgc atggtacgac gaagcaggta acgtttatgt
    12001 tggccgcaac gaagaagaag tgcgcaagga aaataacctc ggtgccgacg ttgccctgcg
    12061 tcaggacgaa gacgttctcg acacctggtt ctcttctgca ctgtggacct tctctaccct
    12121 tggctggccg gaaaacaccg acgccctgcg tcagttccac ccaaccagcg tgatggtatc
    12181 cggcttcgac atcatcttct tctggattgc ccgcatgatc atgatgacca tgcacttcat
    12241 caaagatgaa aatggcaaac cgcaggtgcc gttccacact gtttacatga ccggtctgat
    12301 tcgtgacgac gaaggccaga agatgtccaa atccaagggt aacgttatcg acccgctgga
    12361 tatggttgac ggtatttcgc tgccagaact gctggaaaaa cgtaccggca atatgatgca
    12421 gccgcagctg gcggacaaaa tccgtaagcg caccgagaaa cagttcccga acggcattga
    12481 gccgcacggc accgatgccc tgcgcttcac cctggcggcg ctggcgtcta ccggtcgtga
    12541 catcaactgg gatatgaagc gcctggaagg ttaccgtaac ttctgtaaca agctgtggaa
    12601 cgccagccgc tttgtgctga tgaacacgga aggtcaggat tgcggcttca acggtggtga
    12661 aatgacgctg tcgctggcgg accgctggat tctggcagag ttcaaccaga ccatcaaagc
    12721 gtaccgcgaa gcgctggaca gcttccgctt cgatatcgct gcaggcattc tgtatgagtt
    12781 cacctggaac cagttctgcg actggtatct ggagctgacc aagccggtaa tgaacggtgg
    12841 aaccgaagcc gaactgcgcg gtactcgcca tacgctggtg actgtactgg aaggtctgct
    12901 gcgcctcgcg catccgatca ttccgttcat caccgaaacc atctggcagc gtgtgaaagt
    12961 actttgcggt atcactgccg acaccatcat gctgcagccg ttcccgcagt acgatgcatc
    13021 tcaggttgat gaagcggcgc tggccgacac cgagtggctg aagcaggcga tcgttgcggt
    13081 acgtaacatc cgtgcagaaa tgaacatcgc gccgggcaaa ccgctggagc tgctgctgcg
    13141 tggttgcagc gcggatgcag aacgtcgcgt aaatgaaaac cgtggcttcc tgcaaaccct
    13201 ggcgcgtctg gaaagcatca ccgtgctgcc tgccgatgac aaaggtccgg tttccgttac
    13261 gaagattatc gacggcgcag agctgctgat cccgatggct ggcctcatca acaaagaaga
    13321 tgagctggcg cgtctggcga aagaagtggc gaagatcgaa ggcgaaatca gccgcatcga
    13381 gaacaagctg gcgaatgaag gctttgtcgc ccgcgcaccg gaagcggtca tcgcgaaaga
    13441 gcgtgagaag ctggaaggct atgcggaagc gaaagcgaag ctgattgaac agcaggctgt
    13501 tatcgccgcg ctgtaatcaa caccgtgatg aaaacgaagg ccggagcatg ctccggcctt
    13561 ttttatctct tacagaaatg gtaaagaagg cataattccc cgtgaaatac tggctaagaa
    13621 gcctttatct ggttgttctt ctttattgat taaaggaagg tcatccaaat cgcccagcaa
    13681 atacgtattt tttgcctgcc agtcaatcat ccatattttc agcagtggat aagccagacc
    13741 gcccgtaatc ccggatatca ccaccaacgc acacatgcga taaagcatac cgtggtatgt
    13801 taaagttgag cgaaaacgaa tacgcccatc attcagtgac aggttgctca taaaatgatt
    13861 tcgcaacgac accgttaaat aactggtgct aacagcaatc ccaaaataat agattaactg
    13921 cgcgattatc attttacgtt gcatttccat aaattgctgt aaattctcaa tatcatcatt
    13981 tgcatacaca gaactatcat acgcatttaa tatttgatcg aagataatat aaccagcaac
    14041 agcgagaaaa ggtaataaag ctaaaaatgc gagaatggca tattttatac aatacgtagt
    14101 atctaatttc accttgaaac gatgtatacc gaaactggta ttgctccaga gaaaactcat
    14161 taccagacta tataaagtac cattaaaaat accaatggaa acaataccaa ctattgccat
    14221 cagaaccaca gatataataa cactacttga actattggca tgtagcatct ttgtcgagat
    14281 aaagaaaaca gtccccatcc caatggccat taaaatcggc aagaaaaagg ttacccacca
    14341 gaaccctttc aaagagcaat taaaactaaa tcttacgccg ttgagactag tcatcaaggc
    14401 ctgataacgc agtccttttg ctgccataaa tataagcaaa accaacagtg acaaagtcaa
    14461 aacacagtca acaagcggca tatctgctga cactgtcatt aagattgcga aatagaaaaa
    14521 aacaaaaaca agacaactaa caaaaacatt cccaccggta atcccataag aaaatcgttg
    14581 tccgttaact tccatattag catagagata acgcttacat ttcattaatg cccatggtaa
    14641 atagatacct agcgttataa tcgttaacaa cacattcacc acacaaataa gaaaatatct
    14701 ctcacctgta ccatgaaaaa caaacgaatg ggacggaaca tccatttcat taataacttg
    14761 agccataaaa attccctgaa ttaaaaaatt cattgatata atttatagat acagacagta
    14821 aaatgttctg ccacgttaca atactcttat cagtaatagg ctggcaaaaa ctttattgct
    14881 ttataagacg cttgcgcacg taagaagaga gtggtattaa acaaatgtat aattacttta
    14941 tttttattgg gttaaactat gaataacatt gcgccgcaat cacctgtaat gcgtcgcctg
    15001 acgttgcagg ataatcctgc tatcgcccgc gtcattcgtc aggtatccgc cgaatacggt
    15061 cttaccgctg ataaaggcta caccgtcgcc gatccgaatc ttgacgagct gtatcaagtg
    15121 tatagtcagc ctggtcatgc atattgggtg gttgagtacg agggtgaagt ggtcggcggc
    15181 ggtgggattg cgccattagc aggtagtgaa tcggacattt gcgaactgca aaagatgtat
    15241 tttcttccgg ctattcgcgg taaagggctg gcgaaaaaac tggccttaat ggcgatggag
    15301 caagcacgag agatgggctt caaacgctgc tatctggaaa cgaccgcttt tttaaaggaa
    15361 gccattgcgc tttatgagca tttgggcttt gagcatatcg actatgcgct tggctgcacg
    15421 ggccatgtcg attgtgaagt gcggatgcta cgcgaactct aaaaaaatgc ccgctagtgt
    15481 gtgctatcgg gcattttaat caattaatta gtggcgaaca ccgtcatcgt cttcatcgac
    15541 aaaatcttca tcgtcgccgt cttcgccatt gggatcttca aagtaagtgc cccaaccgtc
    15601 gtactcaacg tcaaatttct ccgccagcgt catcagttgt tcaacctggg catcgatcag
    15661 atcggcattc aacgcgcact cgctgaggat gtcgcagcaa atcacgatat caccatcttc
    15721 aacttccagc tcttctggat cggtcacttc gtaaccgagt ttaaacgctt caactgctgc
    15781 tttttccagg gtttccagat cgtctgcgga aagatggtgt tcgatggtgt acagcgcgtc
    15841 cggatcgctg ccatcttcca gtaattcttc aataatcaaa cgtgtttctt cacgctgttc
    15901 ttccagttgt tccgggtttg ccatggctca ttcctcttaa tgtcctgccg atactcttat
    15961 tgtcacacac cactgacatt gcctccacct ttgtgacaaa gatttatgct ttagacttgc
    16021 aaatgaataa tcatccatat aaattgaatt ttaattcatt gaggcattag ccacaggagg
    16081 gatctatgtc cgggttttat cataagcatt tcctgaaatt actcgatttc acgccagctg
    16141 aactcaacac cttgttgcag ttagccgcga agctgaaagc cgataagaaa agcggtaaag
    16201 aagaagctaa actcactggt aaaaacatcg cgctcatctt cgaaaaagac tcgactcgta
    16261 cccgatgctc tttcgaagtt gccgcatatg accagggtgc tcgtgttact tatctcggcc
    16321 caagcggcag ccagattggt cataaagagt cgattaaaga cactgcccgc gtgcttggtc
    16381 gcatgtatga cggtattcag tatcgcggct atggtcagga gattgtcgaa acactggcgg
    16441 aatacgctgg cgtgccggta tggaacggcc tgaccaatga gtttcacccc acgcagctgc
    16501 tggcggatct cctcaccatg caggagcatt tgcccggtaa aacattcaac gaaatgacgc
    16561 tggtctatgc aggtgacgca cgtaacaaca tgggcaattc gatgctcgaa gctgcggcgc
    16621 ttaccggtct ggatttgcgt ctggtcgcgc cacaggcatg ctggccggaa gctgcgctgg
    16681 ttacggaatg ccgcgctctg gcacagcaaa atggcgggaa tattacgctg acggaagatg
    16741 tagccaaagg agtagaaggt gctgacttta tctataccga tgtgtgggtg tcgatggggg
    16801 aagcaaaaga gaaatgggcg gaacgaattg cattgctgcg tgattatcag gtgaataaca
    16861 agatgatgca gttgaccggt aacccggagg tcaaattcct ccactgcctg cccgcatttc
    16921 atgacgacca aacgacgctt ggcaagaaaa tggcggaaga gtttggccta catggcggaa
    16981 tggaagtgac tgatgaggtc ttcgaatctg ccgccagcat tgtatttgat caggcggaaa
    17041 accgcatgca taccatcaaa gcggtgatgg tcgcgacgct cagtaaataa ttgatatcgc
    17101 tataaagatg ccgggaaata caaaactatc ccggcatcac attattttat gcagtgatag
    17161 gtctattctt ccacccaatt ttttctattg cagaacgtaa atcttgcggt ggatttaatt
    17221 t
//
LOCUS       DAFGPF010000105        17141 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFGPF010000105 DAFGPF010000000
VERSION     DAFGPF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17141
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.105"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            153..1295
                     /locus_tag="LSX49_003888"
     CDS             153..1295
                     /locus_tag="LSX49_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL7170237.1"
                     /translation="MECDLLMIKIEKVINKNDLKAFIAFPSSLYPDDPNWIPPLFIER
                     NEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGKDTGHFGMIDAIDD
                     PQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYA
                     AHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQIL
                     REIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNIN
                     EAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEAL
                     RDPFARRKIDALEMSWILETNTGMNNMLERIGAEPYKRYRLYEKQI"
     gene            complement(1302..2066)
                     /gene="glcC"
                     /locus_tag="LSX49_003889"
     CDS             complement(1302..2066)
                     /gene="glcC"
                     /locus_tag="LSX49_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001305094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GlcC"
                     /protein_id="HBL7170238.1"
                     /translation="MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFS
                     RSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRA
                     LLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
                     SHNQVLEFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQ
                     RAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMKQG"
     gene            2317..3816
                     /gene="glcD"
                     /locus_tag="LSX49_003890"
     CDS             2317..3816
                     /gene="glcD"
                     /locus_tag="LSX49_003890"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcD"
                     /protein_id="HBL7170239.1"
                     /translation="MSILYEERLDGALPDVDRTSVLMALREHVPGLEILHTDEEIIPY
                     ECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRVPVVTRGAGTGLSGGALPLEKGV
                     LLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNV
                     AENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSPGFDLLALFTGSEGMLG
                     VTTEVTLKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAE
                     DFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFW
                     AGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNM
                     HPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQMCAQFNSDEI
                     TTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF"
     gene            3816..4868
                     /gene="glcE"
                     /locus_tag="LSX49_003891"
     CDS             3816..4868
                     /gene="glcE"
                     /locus_tag="LSX49_003891"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcE"
                     /protein_id="HBL7170240.1"
                     /translation="MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQT
                     LDVRCHRGIVNYDPTELVITARAGTPLVAIEAALESAGQMLPCEPPHYGEEATWGGMI
                     ACGLAGPRRPWSGSVRDFVLGTRIITGTGKHLRFGGEVMKNVAGYDLSRLMAGSYGCL
                     GVLTEISMKVLPRPRATLSLRREISLQEAMNEIAQWQLQPLPISGLCYFDNALWIRLE
                     GGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQ
                     LIDWGGALRWLKSTADDNQIHRIARNAGGHATRFSAGDGGFAPLPAPLFRYHQQLKQQ
                     LDPCGVFNPGRMYAEL"
     gene            4879..6102
                     /gene="glcF"
                     /locus_tag="LSX49_003892"
     CDS             4879..6102
                     /gene="glcF"
                     /locus_tag="LSX49_003892"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcF"
                     /protein_id="HBL7170241.1"
                     /translation="MQTQLTEEMRQNARALEADSILRACVHCGFCTATCPTYQLLGDE
                     LDGPRGRIYLIKQVLEGNDVTLKTQEHLDRCLTCRNCETTCPSGVRYHNLLDIGRDIV
                     EQKVKRPLPERMLREGLRQVVPRPAVFRALTQVGLVLRPFLPEQVRAKLPAETVKAKP
                     RPPLRHKRRVLMLEGCAQPTLSPNTNAATARVLDRLGISVMPANEAGCCGAVDYHLNA
                     QEKGLARARNNIDAWWPAIEAGAEAILQTASGCGAFVKEYGQMLKNDALYADKARQVS
                     ELAVDLVELLREEPLEKLAIRGDKKLAFHCPCTLQHAQKLNGEVEKVLLRLGFTLTDV
                     PDSHLCCGSAGTYALTHPDLARQLRDNKMNALESGKPEMIVTANIGCQTHLASAGRTS
                     VRHWIEIVEQALEKE"
     gene            6107..6511
                     /locus_tag="LSX49_003893"
     CDS             6107..6511
                     /locus_tag="LSX49_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HBL7170242.1"
                     /translation="MKTKVILSQQMASAIIAAGQEEAQKNNWSVSIAVADDGGHLLAL
                     SRMDDCAPIAAYIAQEKARTAALGRRETKGYEEMVNNGRTAFVTAPLLTSLEGGVPVV
                     VDGQIIGAVGVSGLTGAQDAQVAKAAAAVLAK"
     gene            6533..8704
                     /gene="glcB"
                     /locus_tag="LSX49_003894"
     CDS             6533..8704
                     /gene="glcB"
                     /locus_tag="LSX49_003894"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase G"
                     /protein_id="HBL7170243.1"
                     /translation="MSETITQGRLRIDANFKRFVDEEVLPGTGVDAAAFWRNFDEIVH
                     DLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPDRVTVET
                     TGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDP
                     QRGEQVIAWVRCFLDESLPLENGSYQDVVAFKVVDKQLHIQLKNGKETTLRTPAQFVG
                     YRGNAAAPSCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVA
                     AVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRHYTAADGSEISLHGRSL
                     LFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPK
                     MHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFIN
                     TGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGM
                     WAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHVLHYHQTNVQSVQANIAQSEFN
                     AEFEPLLDDLLTIPVAENANWSVEEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIH
                     NVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAG
                     NFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH"
     gene            9059..10741
                     /gene="glcA"
                     /locus_tag="LSX49_003895"
     CDS             9059..10741
                     /gene="glcA"
                     /locus_tag="LSX49_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate permease GlcA"
                     /protein_id="HBL7170244.1"
                     /translation="MVTWTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGA
                     ITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDI
                     IRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLC
                     LIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWK
                     GVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKVWRPKNTET
                     AISMGQSACAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFA
                     PGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISI
                     FILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMF
                     PFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMIS
                     PQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGIITLLQAYVFTGMLVS"
     gene            10895..12226
                     /locus_tag="LSX49_003896"
     CDS             10895..12226
                     /locus_tag="LSX49_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBL7170245.1"
                     /translation="MHIGQALDLVSRYDSLRNPLTSLGDYLDPEHISRCLAESGTVTL
                     RKRRLPLEMMVWCIVGMALERKEPLHQIVNRLDIMLPGNRPFVAPSAVIQARQRLGSE
                     AVRRVFTKTAQLWHNATPHPHWCGLTLLAIDGVFWRTPDTPENDAAFPRQTHAGNPAL
                     YPQVKMVCQMELTSHLLTAAAFGTMKNSENELAEQLIEQTGDNTLTLMDKGYYSLGLL
                     NAWSLAGEHRHWMIPLRKGAQYEEIRKLGKGDHLVKLKTSPQARKKWPGLGNEVTARL
                     LTVTRKGKVCHLLTSMTDAMRFPGGEMAELYSHRWEIELGYREIKQTMQLSRLTLRSK
                     KPELVEQELWGVLLAYNLVRYQMIKMAEHLKGYWPNQLSFSESCGMVMRMLMTLQGAS
                     PGRIPELMRDLASMGQLVKLQTRRERAFPRVVKERPGNTPQPRKRASQLLN"
     gene            12403..12819
                     /locus_tag="LSX49_003897"
                     /pseudo
     CDS             12403..12819
                     /locus_tag="LSX49_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973637.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="general secretion pathway protein GspK"
     gene            12816..13993
                     /gene="gspL"
                     /locus_tag="LSX49_003898"
                     /pseudo
     CDS             12816..13993
                     /gene="gspL"
                     /locus_tag="LSX49_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097227.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
     gene            13995..14531
                     /gene="yghD"
                     /locus_tag="LSX49_003899"
     CDS             13995..14531
                     /gene="yghD"
                     /locus_tag="LSX49_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspM family type II secretion system protein
                     YghD"
                     /protein_id="HBL7170246.1"
                     /translation="MLRDKFIHYFQQWRERQLSRGEHWLTQHLAGRSPREKGMLLAAV
                     VFLFSAGYYVLIWQPLSERIEQQETMLQQLVAMNARLKSAAPNIIAARKSGTTTPAQV
                     SRVISDSASAHSVVIKRIAERGENIQVWIEPVVFNDLLNWLKALDEKYALRVAQIDVS
                     AGEKPGMVNVQRLEFGRG"
     gene            15705..16481
                     /locus_tag="LSX49_003900"
     CDS             15705..16481
                     /locus_tag="LSX49_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7170247.1"
                     /translation="MARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPSAHLL
                     ILLGIFGYIMHRTMPDISFPVFLLNGLIPFFIFSSISKRSVSAIEANQGLFNYRPVKP
                     IDTIIARALLETLIYVSVYILLMLIVRMAGEYFEITNFLQLVATWSLLIILSCSVGLI
                     FMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREA
                     VMPGYISEGVSLNYLAMFTLITLFIGLALYRTREEAMLTS"
     gene            16478..>17141
                     /locus_tag="LSX49_003901"
     CDS             16478..>17141
                     /locus_tag="LSX49_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7170248.1"
                     /translation="MIKIENLTKSYRTPTGRHYVFKDLNLEIPSGKSVAFIGRNGAGK
                     STLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQGSLTGRENVKFVARLYAKQEELK
                     EKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFK
                     EKCAQLFKERHKESSFLMVSHSLNSLKEFCDVALFIPRDHQTCLYQNINDAIKLYQND
                     ENL"
BASE COUNT         4191 a         4119 c         4693 g         4138 t
ORIGIN      
        1 ttgtggcgct tcttcgttgg ctgtgatctt atcgtaatca ttaataaata atatttattc
       61 ttattttgta ttcatggtgt tgattattaa gatgccgttc gttgctgttg caacctgttt
      121 ttcatcgtta attatttgtt atccacagag atatggaatg cgatctgctg atgattaaaa
      181 ttgaaaaagt aattaataaa aatgacctta aggcatttat cgcttttccg tcatcacttt
      241 atcccgacga tccaaactgg ataccccctt tattcattga acgcaacgag catttgtctg
      301 cgaaaaatcc ggggacggac catatcatct ggcaggcgtg ggtggcaaaa aaagcggggc
      361 agatagttgg gcgtattacc gcgcaaatag ataccttgca ccgcgagcgt tacggcaaag
      421 ataccggtca tttcggcatg attgacgcca ttgatgatcc gcaggttttt gccgcgttgt
      481 ttggcgcagc ggaagcgtgg ttgaagtcac aaggtgcaag taagatcagc ggtcctttca
      541 gcctgaatat caatcaggaa agcggattac tgattgaagg tttcgataca ccaccctgtg
      601 cgatgatgcc gcacggtaaa ccgtggtatg ccgcgcatat tgaacaattg ggttatcaca
      661 aaggcattga tttactggcg tggtggatgc agcgaaccga tctcactttc tctccggcgc
      721 taaaaaaact gatggatcag gtgcgtaaga aggtgaccat tcgctgcatc aatcgccagc
      781 ggtttgccga agagatgcag atcctgcgtg agattttcaa ttctggctgg cagcacaact
      841 ggggatttgt gccgtttacc gaacatgaat tcgcgaccat gggcgaccaa cttaaatatc
      901 tggtgccgga cgatatgatc tacatcgctg agattgattc tgcaccctgc gcgtttattg
      961 tcggcttgcc aaacatcaac gaggcgattg ccgatctgaa cggatcgctc tttcccttcg
     1021 gctgggcaaa attgctgtgg cgtttaaaag tcagcggtgt gcgaactgcg cgagtaccgc
     1081 tgatgggcgt gcgggacgag tatcagttca gccgcatcgg cccggtgatt gcgttgttat
     1141 tgattgaagc cttacgcgat ccgtttgccc gccggaagat cgatgcgctg gagatgtcat
     1201 ggatcctcga aaccaataca ggcatgaata acatgctgga acgcattggg gcggagccgt
     1261 acaagcgtta ccgattgtat gaaaagcaga tttgatggca gtcacccctg cttcatctcc
     1321 agcggcaccg ccgagcgaat caaatggtgg ccttccagct cgatatcgtg gagattcttt
     1381 ttcacggtcc gcacatgatc gcgtgctgcg cgctgggcga cgtgcggcag ccgctgcaac
     1441 accgcgttgt agatccgcgc atgctggcga tcgatctgct ttttttgctg tggtcgatgg
     1501 tagagattat ttacgctggc aaacaccgaa ttaaacatca ggtcggtcaa tgattgcagc
     1561 gtaaactcca gcacctgatt gtgagaagcc tgacaaatgg cgagatggaa agcgtgatcc
     1621 aactgcgcat gttcgatcag cgaaatctct ttgttgttct cactggcggc gagcattttt
     1681 tcataacagc gggttatcac aacaaaatca gcctgggttc ccagcgttgc cgccagcctt
     1741 gccgattcgc cctccagtaa tgcgcgaacg tcgagcagat cgtacagcgt tcgcggctgc
     1801 gtactgaaca gatggatcag cgggctggtg tcctgcaccc gattaagccg tgcgacacga
     1861 gaatcgcgac cctgcgccgt ttcaataatc ccgcgcccgc gcagcacggt cagcccttca
     1921 cgcagtgcgg agcgtgagaa gccgagcttt tcacacagtc gacgttccga gggaagcggc
     1981 tgaccgacct tcagtacgcc gtcgataatt aaccgttcga tactctctgc aaccacttcg
     2041 caaatagggc gacgttcatc tttcattccc ggacctcgtg cacaggtagg accaattttt
     2101 ctgttcttaa ctcgcaaaac acgcacatca cgtaagtgat tatgttacat caatttaaca
     2161 ttaagttaac caagacaagg tcacagagct ggaaaaaaaa tggtctgacc ggtagctaaa
     2221 gagatagacg aaaacgaaaa gcccgcttaa taactgttca cagaagcagc gcgaaaaaat
     2281 cagctgccac acaacacaac aaagcgaagc ctactcatga gcatcttgta cgaagagcgt
     2341 cttgatggcg ctttacccga tgtcgaccgc acatcggtac tgatggcact gcgtgagcat
     2401 gtccctggac ttgagatcct gcataccgat gaggagatca ttccttacga gtgtgacggg
     2461 ttgagcgcgt atcgcacgcg tccattactg gttgttctgc ctaagcagat ggaacaggtg
     2521 acggcgattc tggctgtctg ccaccgcctg cgtgtaccgg tggtgacccg tggtgcaggc
     2581 accgggcttt ctggtggcgc gctgccgctg gaaaaaggtg tgttgttggt gatggcgcgc
     2641 tttaaagaga tcctcgacat taaccccgtt ggtcgccgtg cgcgcgtgca gccgggcgtg
     2701 cgtaacctgg cgatctccca ggccgttgcg ccgcataatc tctattacgc gccggatccg
     2761 tcctcacaaa tcgcctgttc gattggcggc aatgtggcgg aaaatgccgg tggcgttcac
     2821 tgcctgaaat atggtctaac cgtacataac ctgctgaaaa ttgaagtgca aacgctggat
     2881 ggcgaggcgc tgacgctggg atcggacgcg ctggattcgc ctggttttga cctgctggcg
     2941 ctgtttaccg gatcggaagg tatgctcggc gtgaccaccg aagtgacgtt aaaactgctg
     3001 ccgaagccgc ccgtggcgcg ggtgctgtta gccagctttg actcggtaga aaaagccgga
     3061 cttgcggttg gtgacatcat cgccaatggc attatccccg gcgggctgga gatgatggat
     3121 aacctgtcga tccgcgctgc ggaagatttt atacatgccg gttatcccgt cgatgccgaa
     3181 gcgattttat tgtgcgagct ggacggcgtg gagtctgacg tacaggaaga ctgcgagcgg
     3241 gttaacgaca tcttgttgaa agcgggcgcg actgacgtcc gtctggcaca ggacgaagca
     3301 gagcgcgtac gtttctgggc cggccgcaag aacgcattcc cggcagtggg gcgcatttcc
     3361 ccggattact actgtatgga tggcaccatc ccacgccgcg cgctgcctgg cgtactggaa
     3421 ggcattgccc gtttatcgca gcaatatgat ttacgcgttg ccaacgtctt tcatgccgga
     3481 gacggcaaca tgcacccgtt aatccttttc gatgccaacg aacccggtga atttgcccgc
     3541 gcggaagagc tgggcgggaa gatcctcgaa ctctgcgttg aagttggcgg cagcatcagt
     3601 ggggaacatg gcattgggcg cgaaaaaatc aatcaaatgt gcgcccagtt caacagcgat
     3661 gaaatcacga ccttccatgc ggtcaaggcg gcgtttgacc ccgatggttt gctgaaccct
     3721 gggaaaaaca ttcccacgct acaccgctgt gctgaatttg gtgccatgca tgtgcatcac
     3781 ggtcatttac ctttccctga actggagcgt ttctgatgct acgcgagtgt gattacagcc
     3841 aggcgctgct ggagcaggtg aatcaggcga ttagcgataa aacgccgctg gtgattcagg
     3901 gcagcaatag caaagccttt ttaggtcgtc ctgtcaccgg gcaaacgctg gatgtgcgtt
     3961 gtcatcgcgg cattgttaat tacgacccga ccgagctggt gataaccgct cgtgccggaa
     4021 cgccgctggt ggcgattgaa gcggcgctgg agagcgccgg gcaaatgctc ccctgcgagc
     4081 cgccacatta tggtgaagaa gctacctggg gcgggatgat cgcctgcggg ctggcggggc
     4141 cgcgtcgccc gtggagtggt tcggtccgcg attttgtcct cggcacgcgc atcattaccg
     4201 gcactggaaa acatctgcgt tttggtggtg aagtgatgaa aaacgttgcc ggatacgatc
     4261 tctcacggtt aatggccgga agctacggtt gtctgggtgt gctcactgaa atctcgatga
     4321 aagtgttacc gcgaccacgc gccaccctga gtctgcgtcg ggaaatcagc ctgcaagaag
     4381 ccatgaatga aatcgcccag tggcaactcc agccattacc cattagtggc ttatgttact
     4441 tcgacaatgc gttgtggatc cgccttgagg gcggcgaagg atcggtaaaa gcagcgcgtg
     4501 aactgctggg gggcgaagag gttgcgggtc agttctggca gcaattgcgt gaacaacaac
     4561 tgccgttctt ctcgttacca ggtaccttat ggcgcatttc cttacccagc gatgcgccga
     4621 tgatggattt acccggcgag caactgatcg actggggcgg ggcgttacgc tggctgaaat
     4681 cgacagccga tgacaatcaa atccatcgca ttgcccgcaa cgctggcggt catgcgaccc
     4741 gctttagtgc cggagatggt ggttttgccc cgctaccggc tcctttattc cgctatcacc
     4801 agcagcttaa acagcagctc gacccttgcg gcgtgtttaa tcccggtcgc atgtacgcgg
     4861 agctttaagg agcaggctat gcaaacccaa ttaaccgaag agatgcggca gaacgcgcgg
     4921 gcgctggaag ccgacagcat cctgcgcgcc tgtgttcact gcggattttg taccgcaacc
     4981 tgcccaacct atcagctcct gggcgatgaa ctggacgggc cgcgcgggcg catctatctg
     5041 attaaacagg tgctggaagg caacgacgtc acgcttaaaa cacaggagca tctcgatcgc
     5101 tgtctcactt gccgcaattg tgaaaccacc tgtccttctg gtgtgcgcta tcacaatttg
     5161 ctggatatcg ggcgtgatat tgtcgagcag aaagtgaaac gcccactgcc ggagcgaatg
     5221 ctgcgcgaag gattgcgcca ggtagtgccg cgtccggcgg tcttccgtgc gctgacgcag
     5281 gtagggctgg tgctgcgacc gtttttaccg gaacaggtca gagcaaaact gcctgctgaa
     5341 acggtgaaag ctaaaccgcg tccaccgctg cgccataagc gtcgggtttt aatgctggaa
     5401 ggctgcgccc agcctacgct ttcgcccaac accaacgcgg caactgcgcg agtgctggat
     5461 cgtctgggga tcagcgtcat gccagctaac gaagcaggct gttgtggcgc ggtggactat
     5521 catcttaatg cgcaagagaa agggttagcg cgggcgcgca ataatattga tgcctggtgg
     5581 cccgcgattg aagcaggtgc cgaggctatt ttgcagactg ccagcggctg cggcgcgttt
     5641 gtcaaagagt atgggcagat gctgaaaaac gatgcgttgt atgccgataa agcgcgtcag
     5701 gtcagtgagc tggcggtcga tttagtcgaa cttctgcgcg aggaaccgct ggaaaaactg
     5761 gcaattcgcg gcgataaaaa actggccttc cactgcccgt gtaccctaca acatgcgcaa
     5821 aagctgaacg gcgaagtgga aaaagtgttg cttcgtcttg gatttacctt aacggacgtt
     5881 cccgacagcc atctgtgctg cggttcagcg ggaacatatg cgttaacgca tcccgatctg
     5941 gcgcgccagc tgcgggataa caaaatgaat gcgctggaaa gcggcaaacc ggaaatgatc
     6001 gtcaccgcca acattggttg ccagacgcat ctggcgagcg ccggtcgtac ctctgtgcgt
     6061 cactggattg aaattgtaga acaagccctt gaaaaggaat aacaaaatga aaactaaagt
     6121 cattcttagc cagcaaatgg cgagtgcaat tattgccgca ggtcaggaag aggcgcagaa
     6181 aaataactgg tctgtttcca ttgctgttgc cgatgacggc ggtcatctgc tggcgttaag
     6241 tcgcatggac gattgcgcgc cgattgcggc ttacatcgcc caggagaaag cgcgtaccgc
     6301 cgcgctgggg cgtcgtgaaa ctaagggcta tgaagagatg gtgaacaacg gacgtaccgc
     6361 gttcgtgact gcgccgttac tgacgtcgct ggaaggcggc gtaccggttg ttgtggatgg
     6421 gcaaattatt ggtgccgtgg gcgtttctgg tttaaccgga gcacaggatg cgcaggtcgc
     6481 gaaagcggca gcagcggtgt tggcgaaata agcgaaaacg aggagataaa taatgagtga
     6541 aaccataacc cagggccgtt tacgcattga cgccaatttt aaacgttttg tggatgaaga
     6601 agttttgccg ggaacagggg tggacgctgc ggcgttctgg cgcaattttg atgagatcgt
     6661 tcacgatctg gcaccagaaa atcgtcagtt gctggcagaa cgcgatcgca ttcaggcggc
     6721 gcttgatgag tggcatcgca gcaatccggg gccggttaaa gataaagcgg cctataaatc
     6781 tttcctgcgt gaactgggct acctggtgcc acaaccggat cgcgtgacgg tggaaaccac
     6841 gggcattgac agcgaaatca ccagccaggc ggggccacag ctggtggttc cggcaatgaa
     6901 cgcccgctac gcgctgaacg cggcgaacgc tcgctggggc tcactgtacg atgcgttata
     6961 cggcagcgac atcatcccgc aggaaggggc gatggtcagc ggctacgatc cgcagcgcgg
     7021 tgagcaggtt atcgcctggg ttcggtgttt cctcgatgaa tcactaccgc tggaaaacgg
     7081 cagctatcag gatgtggtgg cgtttaaggt ggttgataaa caattacaca tccagttgaa
     7141 aaatggtaaa gaaaccacgt tacgcacccc ggcgcagttt gtcggttacc gtggcaatgc
     7201 cgctgcgccg tcctgcattt tgctgaaaaa taacggcctg catattgagc tgcaaatcga
     7261 tgccaacggg cggattggca aagacgatcc ggcgcatatc aacgatgtta tcgtcgaagc
     7321 ggccatcagt accattctcg actgcgaaga ttcggtcgcg gcggttgatg cggaagataa
     7381 aatcctgctg taccgcaacc tgctgggcct gatgcagggg actctgcaag agaaaatgga
     7441 aaaaaacggt cggcaaatcg tgcgtaaact gaatgacgat cgtcattaca ccgccgccga
     7501 tggctctgaa atttctctgc acggacgctc gctgctgttt atccgcaacg tgggtcattt
     7561 gatgaccatt cctgtgattt gggacagcga aggcaatgaa atcccggaag gcattcttga
     7621 tggcgtcatg actggcgcta ttgccctcta tgatttaaaa gtgcagaaaa actcgcgcac
     7681 tggcagcgtc tatattgtga aaccgaaaat gcacggtccg caggaagtgg cgttcgccaa
     7741 caaactgttt acccgcattg agacaatgct cggtatggca ccgaataccc tgaaaatggg
     7801 cattatggat gaagaacgcc gaacctcgct gaacttgcgt agctgtattg ctcaggcgcg
     7861 caaccgcgtg gcgttcatca ataccggttt cctcgaccgt accggcgatg agatgcattc
     7921 ggtgatggaa gctggcccga tgctgcgtaa aaaccagatg aaatcgacgc cgtggatcaa
     7981 agcctacgag cgtaataatg tgctttccgg tctgttctgt gggctgcgcg gtaaagcgca
     8041 aatcggtaaa ggcatgtggg caatgccgga cctgatggca gacatgtaca gccagaaggg
     8101 cgaccaactg cgtgccgggg caaacacagc ctgggttccg tcaccaaccg ctgctacgct
     8161 ccatgtgctg cactaccacc aaaccaacgt acagagcgtg caggccaaca ttgcccagag
     8221 cgagttcaat gctgaatttg aaccgctgct ggacgatctg ttgaccattc cggttgctga
     8281 aaacgctaac tggtcggtgg aagagatcca acaagagctg gataacaacg tgcaggggat
     8341 tctggggtac gtggtgcgtt gggtggagca ggggattggt tgttcaaaag tgccggatat
     8401 tcacaacgtg gcgctgatgg aagaccgcgc aacgctgcgt atctccagcc agcatatcgc
     8461 caattggtta cgtcacggta ttctgaccaa agaacaggtg caggcgtcgc tggagaatat
     8521 ggcgaaagtg gttgatcagc aaaacgctgg cgatccggct tatcgtccga tggcggggaa
     8581 tttcgctaac tcgtgtgctt ttaaagctgc cagcgattta atcttcctcg gcgtgaaaca
     8641 gccaaacggc tataccgaac cgttattaca cgcctggcgt ttacgcgaaa aagaaagtca
     8701 ttaatagcgt caaaaaagcc ccggcaagtt ttattgtcgg ggctatgata gtaactgcgg
     8761 tagtacattt atcccggaaa taaccggagc gattatcagg gtttaacaat attaaatacc
     8821 cgtagcgcat tactagcggg cctaaaacaa caatatggac atcttaacga tactctgcgc
     8881 ctgcgtgtgc ggaacagaaa cccttacccg atatacttgt tatgccagag gtagcaattg
     8941 cgttagcagc gtactgttgc tgtaaagtat aacgcctata ttttacagtt cagtcctctt
     9001 ttgcttatta caaccttaag tatatcaagc atataaagat aataagagac tgaacaatat
     9061 ggttacctgg acccaaatgt atatgccgat gggaggactg gggctatccg ctctggtcgc
     9121 cctgatcccg ataatattct tcttcgttgc actcgcggta ttacgtctga aaggacatgt
     9181 cgccggagca ataaccctta tattatctat tctgattgcg atattcgcct ttaaaatgcc
     9241 gattgatatg gcatttgctg ctgcgggcta tggctttatt tatggattat ggcctattgc
     9301 gtggattatt gttgcggcgg tgttcctgta taaattaacc gttgccagcg gtcagtttga
     9361 tattatccgc agctcggtta tctccatcac tgacgatcag cgtttgcagg tgttactgat
     9421 tggtttctcc tttggcgcgc tgctggaagg ggcggctggc tttggtgcgc cggtggcgat
     9481 taccggtgcg ctgctggtgg gcctgggctt caaaccgtta tacgcggcgg ggctgtgtct
     9541 gattgccaac actgcgccgg tggcgtttgg tgcgttgggc gtgccgattc tggtcgccgg
     9601 tcaggtaacg ggaatcgatc cgttccacat tggcgcaatg gcgggacgtc agttaccgtt
     9661 cctgtcggtt cttgtgccgt tctggctggt agcaatgatg gacggctgga aaggggtgaa
     9721 agagacgtgg ccagcggcgc tggttgctgg gggaagcttc gctgtcacgc agttctttac
     9781 ctctaactat attggtccgg aactgccgga tattacttcg gcgctggtga gtatcgtctc
     9841 actcgcttta ttccttaaag tctggcggcc gaaaaatacc gaaacggcaa tcagcatggg
     9901 acaatccgca tgtgcgatgg tggtgaataa accatcttct ggcggtcccg tgccttcaga
     9961 atatagtctg gggcaaatca ttcgtgcgtg gtcaccgttt ttaatcttaa cggtgttggt
    10021 caccatctgg accatgaagc cgtttaaagc gttatttgct ccgggcggcg cgttttattc
    10081 actggtgatt aatttccaga tccctcattt gcatcaacaa gtcttgaaag cggcccccat
    10141 tgtcgcccag ccgacgccaa tggacgcggt gtttaaattc gaccccctct ctgctggtgg
    10201 caccgctatt tttattgcgg cgattatctc tatcttcatc ctcggcgtgg ggatcaagaa
    10261 aggtattggc gtctttgccg aaacgctaat tagtctgaag tggccgatac tgtcgattgg
    10321 catggtgctg gcatttgcct tcgtcaccaa ctattccggt atgtccacca cgctggcgct
    10381 ggtactggct ggtacaggcg tgatgttccc attcttctca ccgtttctcg gctggctggg
    10441 cgtattcctt accggctcgg acacttcttc aaacgccctg tttggttcac tgcaatcgac
    10501 cacggcgcag caaatcaacg tctctgacac cctgctggtg gcagcaaaca ccagcggcgg
    10561 cgtaactggc aagatgatct ccccgcaatc tatcgccgtg gcctgcgccg cgacgggcat
    10621 ggtgggtcga gaatctgaac tgttccgcta caccgtgaag cacagtctga tttttgccag
    10681 cgttatcggc attatcacgc tgttgcaggc gtatgtgttt accgggatgt tagtttcgta
    10741 agtcaataaa gccggatgat cgttaatatc atccggcttc gttgtgcaca gaaaaccccc
    10801 agctaggctg taatgccgat cagttaagga tcagttgacc gatccagtgg ctgtgtaaga
    10861 atccggaaac gctcacttgt ttccggattt ttttatgcac attggacagg ctcttgatct
    10921 ggtatcccgt tacgattctc tgcgtaaccc actgacttct ctgggggatt acctcgaccc
    10981 cgaacacatc tctcgttgcc ttgccgaatc aggtactgta acgctacgca agcgccgtct
    11041 tcccctcgaa atgatggtct ggtgtattgt tggcatggcg cttgagcgta aagaacctct
    11101 tcaccagatt gtgaatcgcc tggacatcat gctgccgggc aatcgcccct tcgttgcccc
    11161 cagtgccgtt attcaggccc gccagcgcct gggaagtgag gctgtccgcc gcgtgttcac
    11221 gaaaacagcg cagctctggc ataacgccac gccgcatccg cactggtgcg gcctgaccct
    11281 gctggccatc gatggtgtgt tctggcgcac accggataca ccagagaacg atgcagcctt
    11341 cccccgccag acacatgccg ggaacccggc gctctacccg caggtcaaaa tggtctgcca
    11401 gatggaactg accagccatc tgctgacggc tgcagccttc ggcacgatga agaacagcga
    11461 aaatgagctt gctgagcaac ttatagaaca aaccggcgat aacactctga cgttaatgga
    11521 taaaggttat tactcactgg gactgttaaa tgcctggagc ctggcgggag aacaccgcca
    11581 ctggatgata cctctcagaa agggagcgca atatgaagag atcagaaaac tgggtaaagg
    11641 cgatcatctg gtgaagctga aaaccagccc gcaggcacga aaaaagtggc cgggactggg
    11701 aaatgaagtg acagcccgcc tgctgaccgt gacgcgcaaa ggaaaagtct gccatctgct
    11761 gacgtcgatg acggacgcca tgcgcttccc cggaggagaa atggcggaac tgtacagtca
    11821 tcgctgggaa atcgaactgg gatacaggga gataaaacag acgatgcaac tgagcaggct
    11881 gacgctgaga agtaaaaaac cggagcttgt ggagcaagag ctgtggggtg tcttactggc
    11941 ttataatctg gtgagatatc agatgattaa aatggcggaa catctgaaag gttactggcc
    12001 gaatcaactg agtttctcag aatcatgcgg aatggtgatg agaatgctga tgacattgca
    12061 gggcgcttca ccgggacgta taccggagct gatgcgcgat cttgcaagta tgggacaact
    12121 tgtgaaatta cagacaagaa gggaaagggc cttcccgaga gtggtaaagg agaggcctgg
    12181 aaatacccca cagccccgaa aaagagccag tcagttgctt aactgactgg cattacagct
    12241 aggctggggg ttccggaaag ctttcagctt tgagccagtt attaaaaccc cttttgattt
    12301 gttaaaacac cttgcggtct ggcaactgca agtgtcaaac aagaaatcaa aagggggtcc
    12361 caatggggaa cgaaaagagc ttagcgcaca cccgatggaa cgcgcgtggt acagggaatg
    12421 gacgccgggc tttatcaaaa actgaaaccg ttggtctgtg cgctgccgat ggcccgccag
    12481 caaatcaaca tcaatacatt agatgtcacg caaagtgtga ttcttgaggc gctgtttgac
    12541 ccgtggttaa gccctgttca ggcgcgggcg ttattacaac aacgtccggc gaagggctgg
    12601 gaagatgtcg atcagtttct tgcacagccg ctacttgcag acgtcgatga gcgtactaaa
    12661 aaacagctaa aaaccgtcct gagcgtggac agcaattact tctggctgcg ttcagatatc
    12721 accgtgaatg agattgaact gacgatgaat tcgttaattg tccgcatggg cccacaacac
    12781 ttttctgttc tctggcatca gacaggagaa agtgagtgag tttcatgctt gagatttttt
    12841 tcccgctttg cgccgctgat cccatccgtt ggcagcgcca tacacccgac gtggagcacg
    12901 gtatctggcc tgacgttgct gatgaatgtc tccagcaatg gctgcaaact gatgcgattc
    12961 gactctacat tcccggcgaa tggatcagcg tctggcaggt tgaactgcct gatgtgcccc
    13021 gcaagcagat accgacgatt ctgcccgcct tgctggaaga agagctgaac caggatatcg
    13081 atgaactgca ttttgccccg ttgaaaatcg accagcaact ggcaaccgta gctgtgattc
    13141 accagcagca tatgcgcaac attgcgcagt ggttgcaggc aaacggcatc acccgcgcta
    13201 ccgtcgcgcc ggactggatg tccattcctt gtgggtttat ggctggcgat gcgcgacggg
    13261 ttatctgccg catcgatgaa tgccggggat ggagcgccgg gcgggcgctg gctccggtca
    13321 tgttccgcgc acagctcaat gagcagaatt taccgatttc actaaccgtg gtcggcattg
    13381 caccggaaga actgtctgca tgggctggtg cggacgcgaa cgcctgaccg ttacggctct
    13441 gcccgccatt accacttatg gcgaaccgga agggaacctg ctaacagggc cgtggcagcc
    13501 tcgtgtcagc taccgaaaac agtgggcgcg ctggcgggtg atgattctgc cgatattgct
    13561 gattctggtt gcgctggtag tggaacgggg cgtgacgtta tggagcgtca gcgaacaggt
    13621 ggcgcaaagc cgcacccagg cggagaaaca gttcttaacg ctattcctgg ggcagaagcg
    13681 gattgtgaat ttacgctctc agatgacgat ggcgctgaaa aaatatcgcc cacaggccga
    13741 cgatacctgg ctgctcgcag aattgtcagc gatcgccagt accctgaaat cagcgtcact
    13801 ttccgacatc gaaatgcgtg gtttcacctt tgatcaaaaa cgccagacgc ttcaccttca
    13861 gctacgggct gcgaactttg ccagcttcga caaactgcgt agcgcactgg cggcagatta
    13921 tgttgtgcaa caggacgcgt tacagaaaga gggtgatgcg gtttccggcg gcgtaacgtt
    13981 gcggaggaaa taacatgtta cgcgataaat ttattcacta ttttcagcaa tggcgtgaac
    14041 gccagttaag ccgtggcgaa cactggctga cacaacacct ggcggggcgt tctccgcgtg
    14101 aaaaaggcat gttactggca gcggtagtgt tcctgtttag cgccggatat tacgtcctca
    14161 tctggcagcc gttgagcgaa cggatagaac aacaggagac gatgttgcag cagctggtgg
    14221 cgatgaacgc gcgactgaag agcgccgcgc cgaatattat tgcggcgcga aaatccggca
    14281 cgacaacgcc agcacaggta tcgcgggtca tcagcgacag cgcttccgcg cactctgtgg
    14341 tcatcaaacg gattgccgag cgtggggaga atattcaggt ctggatagaa cctgtggtgt
    14401 ttaatgacct gctgaactgg ttaaaggcgc tggatgaaaa gtacgcgctg cgggtggcac
    14461 aaattgatgt cagtgcgggt gagaagcctg ggatggtgaa tgtgcagcga ctggagtttg
    14521 ggcgggggta ggtattgcca tttccttaac cccacctgat aacccttagc ccaatggtga
    14581 gtgcggaact gtcaaacccg ctcaccgggc tgagtttcga tgtagcaaga attatctccc
    14641 tccagaccac cacggaatat tcggtaacac tgaaggaacc tgtttttcac catgtagcct
    14701 tcgttaatcg acacctttct cagactgtaa agttgcttaa gtgttttgac acattatgat
    14761 tattaatagt tgtaataaat cattgagtaa caattgatag gccaaaacat ataggataat
    14821 tctagtgtga tctgtatttt gtgtaacctg gaagttagta aaattcctgg agataatcag
    14881 aaagggaatt tcaaataagc ataataattt ccagtgaaac tattcgtcga ttttaagaaa
    14941 tgtctgctca ggtatatcta ctgagggatg gtgttggttg taacactggt taaaataaac
    15001 acacaaaaat aatcaagatg tatattttaa tcgacaaaaa taattactca cggaattatt
    15061 gatgggtgtt aaataacacc gtttaaatgt gatgtaaatc acaaatgtga ctgtaaagag
    15121 ggtgctgtag atataaataa gaagtacatg agtgaatttt aaatagggaa atagtttctt
    15181 gctaaacaat ttattggtaa tcaatcgcat gcgttctggt ttgagataga ttacaggtgt
    15241 tactacgcat aaaattcatg ggtggtatta taatcaagta gttaacagta atagtgaaaa
    15301 ataatttctt gcgaaattag cggcccgttt tgaataagtg tgttccggag taatccagaa
    15361 cgcatgctgc tttacatctt tttcaagcca tattggttaa gcaaaaagaa gtagaaataa
    15421 tttcctgaga aattaactca acattctgaa acggccagtt ttctgaaatt accagaagac
    15481 cgaatacatt catgcctgaa gaatggatta gaagaaacga gacggaaata gatctattta
    15541 tccctgcgga aataatttct gctgaaattg tttgcggcta ttaaaaaggt caaaccgtct
    15601 gactaaattt tatccagtta caaacaagta ttacctccag tgtattggta gctgttaagc
    15661 caggggcggt agcatacctg aagagaatag gatcacatca ccaaatggca agaagtggat
    15721 ttgaagtcca gaaagtcacc gtagaggcat tatttctacg agaaatacga acacgctttg
    15781 gtaagttccg tctgggatat ctgtgggcga ttctcgaacc ctctgcgcat ttgctgatac
    15841 tgttgggcat ttttggttac attatgcacc gcacgatgcc agacatctcg ttcccggtgt
    15901 ttttacttaa tggcctgatt ccctttttta tctttagcag tatcagcaaa cgttctgtaa
    15961 gtgctattga agcgaaccag gggctgttta attatcgccc agtaaaaccc atcgatacga
    16021 tcattgcgcg cgccctgctt gagacgctga tttacgtttc tgtttatatt ctgcttatgc
    16081 tcattgtcag gatggcaggc gaatatttcg agataacaaa ttttttacaa cttgtggcta
    16141 cctggagtct gctgatcatt ctttcatgca gcgtcggctt aatattcatg gtcgttggta
    16201 aaaccttccc cgaaatgcaa aaggttctgc cgatacttct taagcccctt tatttcatct
    16261 cctgcatcat gttccctctg cactcaattc caaagcaata ctggtcatat ctactctgga
    16321 acccactagt gcatgtcgtg gagttaagcc gtgaggctgt tatgcctggc tatattagcg
    16381 aaggtgtgag tctgaactac ctggcaatgt tcacattgat aactctgttc attggtctgg
    16441 cgttatatcg aactcgtgag gaggcaatgc tgacatcatg attaagattg agaatttgac
    16501 gaagtcatat cgcacgccaa cgggtcgaca ttatgtgttt aaggatttaa acctcgaaat
    16561 cccttcagga aaaagtgttg cctttattgg tcgtaatggt gcgggtaaat caacgttact
    16621 gagaatgatt ggtggcattg accgccccga cagtggaaag atcatcacta ataaaacaat
    16681 atcatggcca gtcggccttg caggtggatt tcagggaagt ttaaccggac gcgaaaacgt
    16741 aaaatttgtt gcgcggttat acgcgaagca agaagaactg aaagagaaaa ttgagtttgt
    16801 tgaagaattt gccgaacttg gcaagtactt cgatatgccg attaaaactt actcatcagg
    16861 tatgcgatcg cgtttaggct ttggtttaag catggcattt aagtttgatt attatatcgt
    16921 cgatgaagta acggcggtcg gtgatgccag gtttaaagaa aaatgcgctc aattgtttaa
    16981 agaaaggcat aaagaatcta gctttttaat ggtttcacat agtttgaatt cattgaaaga
    17041 gttttgtgat gtggcgctat tcatacctag agatcatcag acttgtcttt atcagaatat
    17101 taatgacgca attaagttat atcaaaatga tgaaaatttg a
//
LOCUS       DAFGPF010000106        16878 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFGPF010000106 DAFGPF010000000
VERSION     DAFGPF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16878
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.106"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..163
                     /locus_tag="LSX49_003902"
     CDS             <1..163
                     /locus_tag="LSX49_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL7170249.1"
                     /translation="FGQWDQTFAGDAALTSAMLDRILHHSHVVQIKGESYRLRQKRKA
                     GVIAEANPE"
     gene            complement(230..358)
                     /locus_tag="LSX49_003903"
                     /pseudo
     CDS             complement(230..358)
                     /locus_tag="LSX49_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1189..1791)
                     /locus_tag="LSX49_003904"
     CDS             complement(1189..1791)
                     /locus_tag="LSX49_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170250.1"
                     /translation="MKQQYQTRYELLHENYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRSSPSLDDDLVVNLCTSEHLLVHHPMLEG
                     ILLSECERLKQHSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLDDWTKNLKHK
                     SEKDLEQWIIARQGQSEPLTNLMDQYVLMAYRTSVDAAHS"
     gene            complement(1885..2091)
                     /locus_tag="LSX49_003905"
     CDS             complement(1885..2091)
                     /locus_tag="LSX49_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HBL7170251.1"
                     /translation="MATPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKVGGFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            complement(2287..3483)
                     /locus_tag="LSX49_003906"
     CDS             complement(2287..3483)
                     /locus_tag="LSX49_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element ISEc20 family transposase"
                     /protein_id="HBL7170252.1"
                     /translation="MTESSDYESVQVFIGVDVGKDTHHAVAINRSGKRLFDKALPNDE
                     NKLRSLISDLKQHGQILLVVDQPATIGALPVAVARSEGVLVGYLPGLAMRRIADLHAG
                     EAKTDARDAAIIAEAARTLPHALRTLKLADEQIAELSMLCGFDDDLAAQTTQASNRIR
                     GLLTQIHPALERVLGPRLDHPAVLDLLQRYPSPEKLASLGEKKLAAQLCKLAPRLGKR
                     LAADIAQALAEQTVVVPGTNAAAVVLPRLALQLITLRKQRDEVALAVEQRVLAHPLYP
                     VLTSMPGVGVRTAARLLTEVACRAFASVAHLAAYAGLAPVTRRSGSSIRGEHPSRRGN
                     KALKRALFLSAFAALRDPLSRAYYTRKMSQGKRHNQALIALARRRCDVLFAMMRDGTF
                     YTPQAS"
     gene            4283..4423
                     /locus_tag="LSX49_003907"
     CDS             4283..4423
                     /locus_tag="LSX49_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001418354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulating family protein"
                     /protein_id="HBL7170253.1"
                     /translation="MNSHTRYKLTLAELEAFNSAVDNRLAELTANFTSACWLQSCHLS
                     VR"
     gene            5063..5632
                     /locus_tag="LSX49_003908"
     CDS             5063..5632
                     /locus_tag="LSX49_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HBL7170254.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRFPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGECKGKKHYHLMLLVN
                     RDTWCRAGDYRAPGSLAGMIEQAWCSALGVDAGCHATLVHFPAWPAVWLARNDDTGFQ
                     QVLERADYLAKEHTKAHCTGERNFGCSRG"
     gene            5798..6199
                     /locus_tag="LSX49_003909"
     CDS             5798..6199
                     /locus_tag="LSX49_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170255.1"
                     /translation="MYAKSFLALDSNGRLTGARTVQAAPYAHYTCHLCGSALRYHPQY
                     DTELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGERYCTHCQTGGFSIPRTTQEEICEF"
     gene            6187..6597
                     /locus_tag="LSX49_003910"
     CDS             6187..6597
                     /locus_tag="LSX49_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HBL7170256.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPSCGTGVYSREGGLQEGNWKDRN"
     gene            6881..8500
                     /locus_tag="LSX49_003911"
                     /pseudo
     CDS             6881..8500
                     /locus_tag="LSX49_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            8580..8872
                     /locus_tag="LSX49_003912"
                     /pseudo
     CDS             8580..8872
                     /locus_tag="LSX49_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312320.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
     gene            complement(8912..9946)
                     /locus_tag="LSX49_003913"
     CDS             complement(8912..9946)
                     /locus_tag="LSX49_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase"
                     /protein_id="HBL7170257.1"
                     /translation="MKDYLQTVTGPVAREDMGLTLPHEHLFNDLSSVVDAPCYPFSQR
                     LVDKKVTAEIQWALKHDPYCCADNMDRKPIEDVIFEINNFISLGGRTIVDATGSESIG
                     RDAQALREVALKTGLNIVASSGPYLEKFESQRIHKTVDELAATIDKELNQGIGDTDIR
                     AGMIGEIGVSPTFTEAEHNSLRAASLAQINNPHVAMNIHMPGWLRRGDEVLDIVLGEM
                     GVSPNKVSLAHSDPSGKDVAYQRKMLDKGVWLEFDMIGLDITFPKEGIAPGVQETADA
                     VAHLIELGYADQLVLSHDVFLKQMWAKNGGNGWGFVPDVFLAYLAERGVDKTILKKLC
                     IDNPGRLLTA"
     gene            complement(9949..10914)
                     /locus_tag="LSX49_003914"
     CDS             complement(9949..10914)
                     /locus_tag="LSX49_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBL7170258.1"
                     /translation="MKKNKYSTPLWMLATILAGMLSPMQSAVNGQLGHWLQDGNACAV
                     ISFASGLVVMFFIIMARKETRQQFAAIPSLIKNRKVPLWNWFAGLCGAMVVFSEGASA
                     SALGVATFQTALISALLLSGLLCDRFGIGVDEKKYFTPYRIIGALFAVIATIFVVSPQ
                     WHSTSFILLAILPFLAGLLAGWQPAGNAKVAEATGSMLVSITWNFIVGFCVLGTALAI
                     RVALGHVTVQLPDVWWMYLGGPLGLMSIGLMAILVRGLGLLMLGVASTAGQLLGSVLI
                     DVLIPSLGNTVYLVTIIGTLFALVGAIVTTIPEYRTSKTMKKMEV"
     gene            complement(10968..11726)
                     /locus_tag="LSX49_003915"
     CDS             complement(10968..11726)
                     /locus_tag="LSX49_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBL7170259.1"
                     /translation="MNNTKKSLKVLFIGESWHIHMIHSKGYDSFTSSKYEEGATWLLQ
                     CLKNSQVDVTYMPAHTVQIAFPEDVAQLEQYDAIVISDIGSNTFLLQNDTFYQLRIKP
                     NALELIKEYVNNGGGLLMIGGYLSFMGIEAKANYKNTVLADVLPVTMLDGDDRVEKPE
                     GVIAQPSQPEHPVIKGFSEYPFFLGYNRAIAKENAEVVLTINNDPLLVFGNYHNGKIA
                     CFMSDCSPHWGTQQFMSWPFYTALWVNILTHIAR"
     gene            complement(11740..12954)
                     /locus_tag="LSX49_003916"
     CDS             complement(11740..12954)
                     /locus_tag="LSX49_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462448.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL7170260.1"
                     /translation="MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELAR
                     LGYLTRCHGGAFIVLDSLDTIAKNEIAYALENYDTAQGIKKGHSTMKSQVCVIGSFNV
                     DIISYLPRLPTIGESLLASNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYA
                     INFMNSSKIYKSIIYQTKETQTGTATILVNEGTGDNVIAIYPGANMTMSSDEITIQKE
                     AIINSDVILLQLETNYTALQQAITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNE
                     TEAGLLSGIDVHDLESAKRAAEAIHNKGVKNTVITLGSKGSLAFDGKKFIHSPAFPAV
                     VKNTAGAGDAFNGALASGLAKGKSLESALCYASAFASLAVETSNASDMPEHESVIHRI
                     QSIHYQQTIFTH"
     gene            complement(13150..13488)
                     /locus_tag="LSX49_003917"
                     /pseudo
     CDS             complement(13150..13488)
                     /locus_tag="LSX49_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13956..14729)
                     /locus_tag="LSX49_003918"
     CDS             complement(13956..14729)
                     /locus_tag="LSX49_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HBL7170261.1"
                     /translation="MIKHTLLVPFFFSALPAYAGLTSITAGYDFTDYSGEHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVNAWQGGVSLYTGPVITSYRYTH
                     YDSSDAGSSYSNMISVRLKDPRGAGYTQLWLSRGTGAYTYDWTPETRYGSMKSISLQR
                     IQPLTEQLNLGLTAGKVWFNTPTDDYNGLQLAAHLIWKF"
     gene            complement(14731..15255)
                     /locus_tag="LSX49_003919"
     CDS             complement(14731..15255)
                     /locus_tag="LSX49_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL7170262.1"
                     /translation="MIIDESAGEVVIGANTRICHGAVIQGPVVIGANCLIGNYAFIRP
                     GTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVANQAYLGAQVRTSNHRLDEQ
                     PVSVRTPEGIIATGCDKLGCYIGKRSRLGVQVIILPGRIISPNTQLGPRVIVERNLPS
                     GTYSLRQELIRTGD"
     gene            complement(15290..16486)
                     /locus_tag="LSX49_003920"
     CDS             complement(15290..16486)
                     /locus_tag="LSX49_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL7170263.1"
                     /translation="MKTLLFIFMTIAMLLWFLSTLRRKPCQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     HGLKYATCDQVFLSDADTFVPPDNDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQFLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVLYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWVGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGT
                     EKLSEA"
     gene            complement(16500..>16878)
                     /locus_tag="LSX49_003921"
     CDS             complement(16500..>16878)
                     /locus_tag="LSX49_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBL7170264.1"
                     /translation="ISSLEYIIENETPQDVEITRVYTMNNTDRHQDHIAVYQASMVAC
                     RYIPQILGYETPSTCLSFLPQVFESVDEVHFNKKILALQKHKSQIHRRYIQPEYIIAQ
                     AKFRGQQVSHSMCEGFVVHKMVL"
BASE COUNT         4381 a         4003 c         4219 g         4275 t
ORIGIN      
        1 gttcgggcag tgggatcaaa cgttcgccgg tgatgcagca ctgacctcag cgatgctgga
       61 ccgtatctta caccactcac atgtcgttca aatcaaagga gaaagctatc gactcagaca
      121 gaaacgaaaa gccggggtta tagcagaagc taatcctgag taaaacggtg gatcaatatt
      181 gggccgttgg tggagatata agtggatcac ttttcatccg tcgttgacac attgccttaa
      241 tctccgcaaa gataacctcg tcattccgga cattctctgc caggcatatg tcgatgtaat
      301 ccataaacga tttcagctta acccttttgt ggccggtctt tctggctggc ggttcagggg
      361 atgttttctg gttatcgtgt accacaaaac tgggatattg ccccgatagt cacatttcag
      421 attgatcgcg gtctgaagat gtggcactga ggtaacgtgc tggtgtcact ggtattgctg
      481 aagttatggt ttttcggggt caggtgagcc tgttgtgtgt atgctttttg ttcagatcag
      541 aggggggctg tgcggacagc ggcttttgtc tccgggcatt cacgcctgaa cgatgaatgc
      601 gattttcagc aatatttgtc tttgtgacac tctctggttg agaagctaat gcgcgcccct
      661 gtttccacag agaatgaggc ttgccatcag ccgaaacatc agtattccac gccatacaga
      721 cggcgcctga ccatgtgctg atgcaggtaa aatgtttcaa ctacaactgt tcgggttgct
      781 atgcaacgaa acagcgattc tcacgatctt taactgcaac gtttttccgc ctgaaagctg
      841 actgcctcct gctgaggtgg gaggctatga ttcagtgcgt ttatagtctc cggggtatgc
      901 atgtaccgga gcataccatt tctggtggat aacaagccgg cacattcagc ctgcagtgaa
      961 gatggaggca cctggttgtg aagaacgttt ctgcccgtgg ctgcttcgca tcatcaatgg
     1021 tattcatacc cgctcagaaa tgaccgggtg ctgaagccct ccgttatcgc gcagtataat
     1081 gacgtatatg atctgtggac gagtgagcgg cgtgcctgat gtacgccgct attactgtat
     1141 tttaccacag ggctggtttt ctgctgccag ccctgtggtt atcagacatc aactgtgagc
     1201 ggcatcaacc gatgtacggt atgccataag cacgtactga tccatcagat ttgtcagtgg
     1261 ttcactctga ccctgacgtg caatgatcca ttgctccaga tctttttctg atttgtgttt
     1321 caggtttttc gtccagtcgt caaggctgtt tccggtcatt aagtcaagcc agcagagcca
     1381 gaccagtttg agacgtaact ccgtgccgcc aaactgacgg aagaggctga tcagtttgtt
     1441 tgccagagaa tgttgcttca ggcgctcaca ttcagacagc aggatccctt ccagcatcgg
     1501 atgatgaacc agcaggtgtt cgctggtgca taaattcacc accagatcat catccaggga
     1561 cggggagctc cgtttgtccg gaccataaat cagccggtgc agactctggg gaacgatggc
     1621 aatctccggt ttttcgccat tgaatgacac ccacccgggc gtcagattat ggaaatagta
     1681 gatattcgga tgacacacgc cccatgatac ggcgtgccgg gtgaagccgg tcagccattt
     1741 ctggtagttt tcatggagca gctcgtaacg ggtctgatac tgttgtttca ttttcatatt
     1801 cctcacgggg gataacaggc agcagagcgc cgccggcagg ccggagattg cgtctgcttt
     1861 gggcgaaggg ttagtggtta aaaattacgg acgggactgt gcaatacgcg cctgcagcca
     1921 ggcttccact tcacttttca gccagcggga gctgcgcccc attttgatgg gggcaggaaa
     1981 gcccccaact ttgatgagtt tgtaaaacca cttatcggtt aagccggtca gttgagtgat
     2041 aaacgccatg tcgaccatct ggtcatccat cagcgaaact ggggtagcca tgagaatgtt
     2101 cctccggatg ttgttaaacc agccggtgtg gtcatgaaaa cagcgcgcca ccttcaccgg
     2161 cataacaacc ggggagaaac gtaaaaaata atcgggaatc tggctgtccg gagataaacg
     2221 gggggattgc gatggcagag ccgtagcgga atcccggggg gtgcccctat taagttgtca
     2281 agcatgttat gacgcctgcg gggtataaaa agtcccgtcg cgcatcatgg cgaacagaac
     2341 gtcgcagcgt cgtctcgcca gggcgataag cgcctgattg tgtcgttttc cctgactcat
     2401 tttgcgggtg tagtaagccc tggagagcgg atccctgagc gcggcgaagg ccgacaggaa
     2461 caacgcccgt ttgagagctt tattaccccg tcgcgaggga tgctcaccgc gtattgacga
     2521 gccggatcgc cgagttaccg gcgcaaggcc agcataagca gcgagatgtg cgacagaggc
     2581 gaaggcgcgg caggcgacct cggtgaggag tctggctgcg gtcctgacac cgactccggg
     2641 catactggtc aggaccgggt aaagagggtg agcaagaact cgctgttcta ccgcaagcgc
     2701 cacctcgtct ctttgcttac gcagcgtgat gagctggagt gccagacgtg gcagtactac
     2761 ggcagcggca ttcgtgccgg gaacgacgac ggtttgttcg gccagtgcct gagctatgtc
     2821 tgctgcaagg cgtttaccca gacgaggcgc aagtttgcag agctgggctg ccagcttctt
     2881 ctcacccagc gaagcgagtt tttctggtga gggatatcgc tggagaagat cgagtaccgc
     2941 cgggtgatca agtctcggac cgagaacgcg ctccagtgcc ggatgtatct gggtcagaag
     3001 gccgcggata cggttgctgg cctgcgttgt ctgtgcggca agatcatcat cgaagccgca
     3061 gagcatggag agttcggcga tttgctcgtc agccagtttc agcgtgcgta gcgcgtgagg
     3121 cagggtacgg gcagcttcgg caatgatggc agcgtcacga gcatcagttt tagcttcacc
     3181 ggcgtgtaag tcggctatgc ggcgcatggc cagtccaggg aggtatccga caaggactcc
     3241 ttctgagcgg gcaacggcga caggtaacgc accgatggta gctggctgat caacaaccag
     3301 cagtatctga ccatgttgtt tcaggtcaga tattagcgac ctgagtttgt tttcgtcgtt
     3361 gggtaatgct ttatcgaaca ggcgtttacc tgaacgatta atggctacag cgtgatgcgt
     3421 atctttaccg acatcaacgc cgataaagac ctggacggat tcgtaatcgc tggattcggt
     3481 cattctgtct cccttgtata tgggttaagc agataaccac ggggagcagg taccggcatc
     3541 cacgttacag acggtcccgg caaaagtgcc tgacctgacc cctattagcg gttaccagcg
     3601 ccccaccaga cccggtgaca tcaccccccg gatcatggac gactgggggc agtaatcatg
     3661 ccgggtctgg ctggctaaca ccccattata aggggtacga ataaagtaac gggggtgcga
     3721 aaagatgctt ccgcacgcac gcgcgataaa gaggggatag ttttcgtgag gacagggaga
     3781 gaagcaggcg ttctgataat tgcagagttg ttttcggagg tggttacagt gagtcagccc
     3841 gttcctggcg agcaggagac tgatatcacc gatgggataa ggttgtctga ttggtattat
     3901 aaatataaga agtcatcaga gagtaacgta aaggatttgc cagaataacc taagagagta
     3961 aatctctccg gtaacagagc gctgtgaagc attctgtatc agagtgcaaa tacatgaacg
     4021 ctgatgcgta aaatcagcag tgacacgcca gctcccccta tgcccattcc tgtataagac
     4081 atgaactgag cgtattaatg ctcctgccct gagactgagc cggtgagtga ggggctgaga
     4141 aatccctctt gacactgctc taaccagaaa tacttccccg gttgttgcgg tgcgtccgga
     4201 tccccgataa cggaacacta aggctgtatt gcgggacacc aggtaagtgg cagcccgtaa
     4261 tacgtcagga gacgcgggaa aagtgaattc ccacacgcgt tataaactta cccttgcgga
     4321 gctggaagcc tttaactctg ccgttgacaa ccggctggca gaactgaccg caaattttac
     4381 gagtgcgtgc tggcttcagt cttgtcacct gagcgttcgg taacggaggc gcgggcggta
     4441 atagactgat tttcaggtat taccggctta cggcgtgtgg ttgatattga ggggctgtga
     4501 gtttcgcgta tttgtcagaa acccagacga gttttcctgt atgggacgaa ataaggcagc
     4561 ggcaatacct ggaaaaattt aatatggtat gaaggagaac ctgtcggtta cgcttaatat
     4621 acccggtaca ctgtcagctc aggggataca tgaaccgtta tctcaccagc tacacagtat
     4681 atacacactg acgctgacag tagtcagcag gaccacaata atcagtgcca gcagtatggt
     4741 aacgatacgg tctgtattcc ggtaatagcc gaaggggtcg acagaaccac aatacgggca
     4801 acacactgta ttatgagtaa tcgcgtttcc acagtccctg cacttctttt tgcgtatcac
     4861 catcactccc tcctcacagc cttacccgta accggttttt tacattaaaa aaacaacgct
     4921 gaaaattcaa ccgtcagtcc ggagacgacc gttcgggtta tcacagagtg cctgagacag
     4981 tgccctgccg gaggtcactt cagggactct gcgcattttt tacgacgtgg ctattccgta
     5041 tgaaccatac ggagatttaa ccatgaccta caaatacaac cccttctggc agcaacgtat
     5101 tcgtgagaca gtgcggcacg cactgaatgt tcatccccgc ctgacggcat tgcgggttga
     5161 cctgcgtttc ccggatgtac cggcagcaac ggacgcagct gtgatatccc gcttcatcaa
     5221 tgccctgaaa gcccgaatcg acgcttacca gaaacgtaag catcgggaag gtaaacgcgt
     5281 gcatcccacc actctgcatt acgtctgggc ccgggagttt ggggagtgca aaggtaaaaa
     5341 acactatcat ctgatgctgc tggtcaaccg ggatacctgg tgtcgtgccg gtgattaccg
     5401 cgctccggga tcactggccg gaatgattga acaggcctgg tgcagtgccc tgggggtgga
     5461 tgccggatgc catgccacgc tggtgcattt tccggcctgg ccggcggtgt ggctggcgcg
     5521 taatgatgac accggctttc agcaagtgct ggaacgtgct gactatctgg cgaaggagca
     5581 taccaaagct cactgcaccg gtgagcgcaa ctttggctgc agtcgtggct gagccagaca
     5641 gacgagttat ctgacttcag tgtgatgacg tgttcatggc caccacactg attttccctt
     5701 atgagactga actgaaaccg ccattcacac ctgaccacgc tgcccgtacc gggacggctg
     5761 ttgcctgcgt gtcgtctgac ggtaaggaac atatactatg tacgcaaaat cctttctcgc
     5821 tcttgatagc aacggacgtc tgacgggcgc ccgtactgta caggccgcac cttatgctca
     5881 ctacacctgc cacttgtgtg gcagtgcact cagataccat ccgcaatacg acactgaact
     5941 tccctggttt gaacacactg acgacaggct gacagagcac ggtcaacagt gcccttatgt
     6001 caggccggag cgcagagaaa tacagttgat taaacgtctg cagcaattcg taccggatgc
     6061 cttacccgtg gtgcgtaaag ccagctggca ctgcagacaa tgtcaccacg attattatgg
     6121 ggagcggtac tgcacacact gccagaccgg aggattcagt attccccgga caactcagga
     6181 ggaaatatgc gaattctgaa ctgttatatg gcgaatgaca gcaaaggcca ttttgttacg
     6241 gcgaaagaag cagcgaagca caaccgccag gacgttttgt gctgtgtgtc ctgtggatgc
     6301 ccgttaacac ttcagcgggg caatgacgga caaccaccgt ggtttgaaca tgaccagatg
     6361 actgtcgctg agaaaatcct gctgcgatgc acctggcttg acccggcaga gaaagaggcc
     6421 cgtcgtttgc atctgcaggg tatgacggtt ccggattata cggtgaaggt gagaaagtgg
     6481 ttttgtgtga tgtgtgacga agattatgaa ggagaaaagt gctgcccgag ttgtggtacc
     6541 ggggtataca gcagggaggg ggggctgcag gaaggcaact ggaaggatag gaactgagcg
     6601 gttcagtcgc ggaaatcagt tgtagagctg taatgatatc tccgggagtg ctgcgttggt
     6661 aggggcatcc cgggatagag aaattttagc actttgccct gaatgattgt agacgtcccg
     6721 ggtactcgta ccggtctgag ttattacagt tagatattca ctttttctcc cgcatacttc
     6781 acatctgtca acgacggatg aaaagtggtt cttccgcaac ctgggtggaa gaaaatggat
     6841 gaaactttct ggcgaacaag gatctaagct gttttaagtt atgggcaacg caatgcactc
     6901 tcttaagaca cttctacagt taccttgcgg atggcgatgc agtcgacaaa ttattagctc
     6961 tgacggtata accctccatc tccacggaaa acgcaaaaca gcacaatgtc ctgaatgctt
     7021 taagcgtagc gactctgttc atagttgtcg tcggcgccgg atacagcatc taccctgctc
     7081 agggcagacg ctatggcttg tattttccgt ccgccactgg tactgccgta acccggcttg
     7141 ttaacgtaaa atttttgccg agtcgcttgc tcccttcgcc ggttcacacc agcagtcttc
     7201 acaggcgtta caaaatttac aacgtcaact gggattaata gctggaggtg aggctggaaa
     7261 acgggctgca acggcagcgg gtctccgttg cagtgctgat actcttcttc gcagggttat
     7321 caataccccg gagacgaaac agtcaggcgc gcctcatgtc ggtattgatg agtgggcgtg
     7381 gcatcggggc cactgctgcg gtatgttaat agtcaatctt gatactcacc gtcccctcgt
     7441 cctgcttccc ggccgtgatc agcgtacgct ggcgacctgg ttcagaaaat atccggaaat
     7501 acaggttgtc tcgcgtgatc gcagtggagt ctatgcgaca gcagcacgtg aaggtgcacc
     7561 tcaggccaga caggtggccg atcgatggca cctgctaaaa agtattggtg atgagcctga
     7621 acgaatgatg tacagacata tgcctctgat acgtcttgtt gtcagagagt tatcactgaa
     7681 gaaatcacct gagccagaaa tatctgtgcc tgtagcatcg ctccgtcgtc cggaacgcct
     7741 taaacagcaa acccgcaaaa aacggcatca gcattggaca gaggttatgg ccctgcataa
     7801 caagggatgt agtttcaggg aaatatcccg tattacaggc ctgtcgcgag tgacagtcag
     7861 tcgctgggtg cgttcaggaa cattccctga aatgtcaacc cggcctccaa agcgagggct
     7921 tctggaccca tggagggagt ggttaaaaga gcaacgagaa agtggtaatt ataatgccag
     7981 ccggatatgg cgggaaatgg tggcccaggg ggggacaggc agtgaaacca tcgtcaggga
     8041 tactgttgcc aaatggcgta aaggctggaa cccaccggtt actactgccg caagacttcc
     8101 ttcagtgtcc cgggtaagcc gctggttgat gccctggaga ataatcaggg gcgaagaaaa
     8161 ttatgcatcc cgatttatta gtctgatgtg tgaaaaagaa ccggagttga aaatagcaca
     8221 gcaactggta ctcgagttct accgtattct gaaaacctaa aataaatcac agctaagcag
     8281 ctggttcact cgagttcacg aaagcggctc agcagaactt cggtgcgtag ctgcggggat
     8341 ggaagctgat gctgcggcta tatgtgaggc aatcagcagt cgctggagta atggtgttgt
     8401 cgaaggtcat gtaaatcgcc tgaaggtgct gatacgccag atgtatggtc gagccggatt
     8461 tgaactactt aggcggaggg taatgagtcc actggcatga aaatcttcac ctaggttgcg
     8521 gaagagccac ttttgcactg ttcgtgacag tatggccttt atgtactcac tttgttaccg
     8581 gtagctgaat catcactacc gtgctgcaaa tggtggtgaa cagcatcaat tgtggaatga
     8641 atgttgccga agcgaccaat gcgcctcgtt tccaccatca gtggttgccg gactagctgc
     8701 gtgttgaaaa gggtttagtc cggatacgct caagctgctg gaagcaaaag gtcagaaagt
     8761 ggcgctgaat gaggcgatgg gcagcacgca aagcattatg gttgggtcgg atggtgagtt
     8821 gtacggcgca tccgactcgc gcttggtgga tgatttaacg gcggggtatt aattgacatc
     8881 ccccggcgca gtgtgccggg ggataatggt tttatgcggt caataatcgt ccgggattat
     8941 cgatacagag ttttttgagg atcgttttat cgacgccgcg ctccgccaga taggccagaa
     9001 aaacatctgg aacaaatccc cagccattac cgccattttt agcccacatt tgtttaagga
     9061 agacatcgtg gctgagaaca agctgatcgg cgtatcccaa ctcaatgaga tgagcgacgg
     9121 catcggcagt ctcctgcacc cctggcgcta ttccctcttt cgggaaggta atgtctaggc
     9181 caatcatgtc gaattccagc cagacaccct tatcaagcat tttccgctga tacgccacgt
     9241 cttttcctga cggatccgag tgtgcgagag agactttatt tggcgagacg cccatttcac
     9301 ctaacacaat gtcgagtact tcatcaccgc gacgaagcca gcccggcatg tgaatattca
     9361 tcgccacatg aggattgtta atctgtgcca gcgaggcagc ccgcaagctg ttatgctcgg
     9421 cttcggtaaa tgtcggtgag acacctattt caccgatcat tccggcacga atatccgtat
     9481 cgccaatccc ttgattcaat tctttatcga tcgttgccgc cagttcatca accgttttat
     9541 gaattctctg gctttcaaat ttttccaggt agggaccgga ggaagcaaca atattcagac
     9601 ctgtttttaa tgcgacttct cgtaatgcct gcgcatctcg tccgatagac tcagaccctg
     9661 tggcatcaac aatggtgcga ccaccgagcg agataaagtt attaatttcg aagatcacat
     9721 cttcaatagg tttgcggtcc atattatcag cgcagcaata aggatcgtgt tttaatgccc
     9781 actggatttc tgccgtgact tttttatcaa caagccgttg tgaaaaagga tagcaaggag
     9841 catccacaac agaggaaaga tcgttgaaca gatgttcatg aggaagtgtt agccccatat
     9901 cttcacgggc gacggggccc gtcacagttt gtagataatc tttcatgatt atacctccat
     9961 tttcttcatt gttttcgagg ttctgtattc cggaatagtg gtaacaattg caccgaccag
    10021 tgcaaacagt gttccgatga tcgtgaccag ataaacggta ttgcccagcg atggaattaa
    10081 tacgtcaatc aatactgatc ccagtaactg gcccgccgtt gaagcaaccc ccagcatcag
    10141 taaccccaga cctctgacca aaatggccat taaaccgata gacattagtc caagcgggcc
    10201 gccaagatac atccaccaga catctggtaa ttgaacagtg acgtgcccta atgcgacacg
    10261 aatagctagc gctgtgccta aaacacaaaa tccaacgatg aaattccagg tgattgaaac
    10321 cagcatggat cccgtagctt cagctacttt tgcatttcca gcgggctgcc atcctgcaag
    10381 caaaccagct aagaacggaa gaatggcaag taagatgaaa gaggtagaat gccactgcgg
    10441 tgacacaaca aaaatcgtag caataaccgc aaataatgca ccgatgatgc gataaggggt
    10501 aaagtatttt ttctcgtcga caccgatacc aaagcgatcg caaagtaaac cagacagcaa
    10561 tagcgcggag atcagtgcgg tttgaaacgt tgcgaccccg agtgcgctgg ctgatgcgcc
    10621 ttcagaaaat accaccatcg ctccacagag accggcaaac cagttccaga gaggaacttt
    10681 tcggttttta atcagagaag gaattgccgc aaattgttgc cgggtttctt ttcgcgccat
    10741 aataataaaa aacatcacga ctaaaccact ggcaaaggag ataactgcgc atgcattacc
    10801 atcctgtaac cagtgaccta attgaccatt caccgctgat tgcatagggg agagcatacc
    10861 cgcaagaatc gtggcaagca tccataaggg agttgagtac ttattctttt tcatacatca
    10921 atccttctat tatagtaaat ggggtaactg gagttacccc attattatta tcttgcaata
    10981 tgagtcagta tatttaccca caacgcggta tagaacggcc aggacataaa ctgctgtgta
    11041 ccccagtgcg gtgaacagtc actcataaag caggctattt tcccgttgtg atagttacca
    11101 aagaccagta atggatcgtt gtttattgtt aataccacct cagcattttc tttagcgatc
    11161 gcccggttat aacctaggaa aaaaggatat tcagagaacc ctttaataac tggatgttca
    11221 ggttgtgatg gctgtgcaat aacaccctct ggtttttcga cacgatcgtc accatctaac
    11281 atcgtaaccg ggagcacatc agccagaact gtatttttat aattggcttt tgcttcaatt
    11341 cccatgaatg agagatagcc gccaatcatc aataacccac caccgttatt cacatattct
    11401 ttaatcagtt cgagagcgtt tggttttatg cgaagttgat aaaaagtatc attttgtagc
    11461 aggaaagtat tactaccaat atcactaata acgatggcat catattgttc taactgtgcc
    11521 acatcttcag ggaaggcaat ttgtaccgta tgtgccggca tataggtgac atctacctga
    11581 ctatttttca gacattggag taaccaggtc gcaccttctt catatttact tgaggtaaaa
    11641 ctgtcatatc cttttgaatg aatcatatga atatgccagg attccccaat aaagagcact
    11701 tttagtgatt ttttggtgtt attcattctc tgtcccttct taatgcgtaa aaatagtttg
    11761 ctgataatgt atactctgaa ttcgatgtat cacagattca tgttcaggca tgtcggaagc
    11821 attgcttgtc tccaccgcta gggatgcaaa ggcgctggca taacacagtg ctgattccag
    11881 tgattttcct ttcgcaagtc ctgatgccag agcgccgtta aaagcatccc cggctcctgc
    11941 cgtattttta acgaccgctg gaaacgctgg cgaatgaatg aattttttgc catcaaatgc
    12001 gagcgagccc ttgctaccga gcgtgataac cgtgtttttt acccctttat tgtggatagc
    12061 ttctgcagct cgtttagctg attcaagatc gtgtacgtct atgccggaca gtaaaccagc
    12121 ttctgtttca ttgggggtga tataatcaac atcctgaata agttcgttga cgatatcatt
    12181 atagggtgcc gggttaataa tgaccgggat actgtttttt tgcgccaatg tgatcgcttg
    12241 ttgcagagcg gtataatttg tttcgagctg cagaagtatg acatcagaat taataatcgc
    12301 ttctttctga atagttattt catcggacga cattgtcatg ttggcaccgg gatagatcgc
    12361 aataacatta tcgccagtac cttcattaac aaggatcgtg gcagttccgg tttgcgtttc
    12421 tttcgtttga taaattatac ttttataaat cttagacgaa ttcataaagt tgatcgcata
    12481 atcactaaag tgatctgtac ctacttttgt tatgaaataa acatcagtat cggcaaagct
    12541 tgctgccagc gcttggttac agccttttcc ccccggtgaa aatataaaat tacttgccag
    12601 aagcgattct ccgatagtgg gaagcctcgg caaataactg atgatatcaa cattaaacga
    12661 accaataacg catacttgac ttttcatagt tgagtggcct ttttttattc cctgggctgt
    12721 atcataattt tcaagcgcat aagcgatttc atttttcgca atagtatcaa gcgagtctag
    12781 gacgataaaa gcaccgccat gacatcgagt cagatagcca agcctggcaa gttcattaag
    12841 atctgatcga atagtttctt tcgttacatt gaggctattg gacagatcgg atacttttac
    12901 agaaccgaat ttactgagtc gtttcaatat ttcatgatgg cgttcaaatt tcatgcttca
    12961 cctcacttca gttacgttaa tatctatcga tgtatattga tgtgataatc accataaagt
    13021 ggcggggaaa agcaaaaaaa agcaaaaata gcctgagaaa aggtaagcgt taatggagaa
    13081 tcatattgat gcttatttat tggtgagaac tacgttccat ggcaggagtt catcaatacg
    13141 gttggaaggt tattccggca gtacgctcag gatatggcgc agatacgctt ccggatcaat
    13201 gtcgttcaga aggcaagtgc cgataagccc atacaacagt gcactgcgct cgccgccgaa
    13261 gaacataaag tttttatttc cgagacagat ggcacaaagg gctttttccg cggcattatg
    13321 tctgcctccg cctgaccgtc aacactgtaa taacagagtg cgccccactg attcagtaca
    13381 cagctgaacc attcacccag tctggatttt tggatagcgt ggcatttttc tccaccatgc
    13441 atgcagtgag tccagtaaca gtttgctctt cttctgcctg accacaagat gtgctggact
    13501 ggtaaacgat ggggatacct gcttacgcga gagcaataag tggctggcca caattctcgg
    13561 tacaaaactc tgctgaatag cagcgatttt cccagcgtgg tgcgtcgttt gcattttact
    13621 ggttctaagt taacaattat ctgttcacta atgactactc taaaaacttg tatcaggact
    13681 atcacttatt taagtgatat tggttgtctg gagattcagg gggcctgtct agagagatat
    13741 aaagatacct tcaccccggt gatgataaaa taaaagtatc tcagctatta aactgatgta
    13801 cgattcgggc aataacttat tcgtatagag caccttttct ctggtgctct atacgaataa
    13861 gttattgccc gaaattaatt atattgttta ttatcaaacc gagttatagc ttttctctga
    13921 aaactaccga ataaaatata ctgatagact gctgcctaga atttccagat caggtgggct
    13981 gcaagttgca gaccgttata atcatcggtt ggggtgttga accacacttt acctgccgtc
    14041 aacccgagat taagttgctc agtcagcggt tgaattcgtt gcaaactgat gctcttcatg
    14101 ctgccgtagc gtgtttctgg cgtccagtcg taggtgtaag cacctgttcc gcggcttagc
    14161 catagttgcg tataaccagc accgcgcggg tccttcagac gcacggaaat catattgcta
    14221 taactactac ctgcatcgct ggagtcataa tgggtatagc ggtaactggt gatcaccggg
    14281 ccagtataga gtgatacgcc gccttgccag gcattgactt cgacatcatc gtaatattta
    14341 gtgtagcgat aaccggtcgt gaaaagcgtt tttggcaaca gggctaggtt aatatcctgt
    14401 cgaaaatcct ggcgggcaaa gaccggcgta ttatccgcaa aggcaatacc cgttcgggtt
    14461 gtcagccagt tattccattt gtaccagact gcaccctggc cgcgagtggc attgaaatgt
    14521 tcagtttcat aatcacgacg cccctgggaa agattaaaaa gcagcgttgc gttttcaact
    14581 tttgctacca gttcagcata cgctaaatta cggttgccat gttcgccaga ataatcggta
    14641 aaatcgtagc ccgcggtaat ggaagttaac ccggcataag cgggcaatgc actaaaaaaa
    14701 aacggcacta ataacgtatg ctttatcatt ttaatctcct gtacggataa gttcttgtcg
    14761 gagtgagtaa gttccactag gtaaattacg ttctacaatc acgcgcgggc caagttgtgt
    14821 gttcggagaa ataattcgcc caggcaaaat aataacttgt acgccaaggc gtgaacgctt
    14881 cccgatataa caacctaatt tatcgcatcc ggtagcgata attccctctg gagttcgaac
    14941 agacacgggt tgttcatcca gacgatgatt actggtacgt acttgtgcgc ccaaatatgc
    15001 ctggtttgca actaccgagt cggcaataaa gcattgcgga ccaatcgttg cttccgcttc
    15061 aataaccgca tttttaattt cggtggcaaa accaattttt acgccattgc tgattattgt
    15121 gccaggacga ataaacgcat aattacctat caggcagttt gcgccaatca ctaccggccc
    15181 ctgaataacg gcaccgtggc aaatacgggt attcgcgccg ataacaacct caccggcact
    15241 ttcatcaata atcacctggt ctgcaatctg aacatttttc tctttagcat taagcttcag
    15301 atagtttttc agttcctgtg acagaaggtt gggaataagc ggttgacgct tccaccagtg
    15361 cggaatagcg ggtgggtttg tcgcgctgag gttcgcgtcc agtaaaaaag gcaataagtc
    15421 cataaataat ccagatggca taagctaata atacatacac aacggaaagc ggtgctaaag
    15481 gcaccaacaa ccagcaacga tgaaaccagg cgctaaatgc accaataaca caaactacgc
    15541 cgacccagat aagcgggaac attgccaaca ccacaccatg tggcccggtg gtgatgaatt
    15601 cattaaacca ggtagtgaga taaataccaa cgccataaag cacaaccaac agcataggaa
    15661 atatactgaa gataccgaag cggctaaata aaagtctttt atgcaggcgc atacagaccg
    15721 cgtagcccac aatccaacgc cgccagcggc gccactcctc acgcggactg ttacattcct
    15781 gtgggtatac gatgcagcga ttcgcctgcc gaatacggta gccgtttgcc accaacgtcc
    15841 aggtgagatc aaggtcttcg actttagtac gatcagagaa accgaactta cgcaatacat
    15901 cagtacggaa catcccgcag gcaccgctga taataaacgg tgcaccgccc agaaactgct
    15961 gtagcgtgcg cttcataaca atcatcggca actttacggt ggcgcggata tgtggcagca
    16021 gacctgcccc ttttaacgcg gtggagggaa ttccgccaac ggcatcagcg ccgcgctcaa
    16081 tttctgccag catatagccc attccatcat tatcaggtgg aacgaaagta tctgcatcac
    16141 ttaaaaatac ttgatcacac gtggcgtatt ttagtccatg cattagtgcg ccacctttac
    16201 cggtgttttt ttgcgtgacg gcaacaaagc ggtcgcccca tttgcgtttg acttccgcca
    16261 tgaccgcttc ggtattgtcc gtggatccgt cgttaacgca aattacccgg caaaaataag
    16321 ggttacgcag cagattatcc agtgactgcg ccagacacgg gccttcgtta taagctggta
    16381 taatggcgtc aatacagcct ttcttttgac agggtttacg tcttagcgta cttaaaaacc
    16441 atagcaacat tgctatggtc atgaagataa ataacaaagt tttcatttct attactccgt
    16501 tacaacacca tcttatggac aacaaaacct tcacacatag aatgactaac ctgttgtcct
    16561 cggaatttgg cttgagcaat tatgtattct ggctgtatgt atcttcgatg gatctggctt
    16621 ttatgctttt gtaatgctaa tattttttta ttaaaatgga cctcatctac agattcaaaa
    16681 acttgaggta aaaatgacag acatgtactt ggtgtttcgt atcctagtat ttgaggaata
    16741 taacgacagg caaccattga tgcctgataa acagcaatgt gatcctgatg cctgtcagta
    16801 ttattcatgg tgtaaactcg agtaatttcc acatcctggg gcgtttcatt ctcaattatg
    16861 tattccagag atgatatc
//
LOCUS       DAFGPF010000107        16868 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFGPF010000107 DAFGPF010000000
VERSION     DAFGPF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16868
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.107"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            6..1238
                     /locus_tag="LSX49_003922"
     CDS             6..1238
                     /locus_tag="LSX49_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL7170265.1"
                     /translation="MYRDTRREYIVRLLRNKDECSVSDLANYFSVTKETIRTDLAWLQ
                     KRGVVSRHHGGVSLKKHLMQNALSQQEYVDMSLLIKQQQQGIGYLTSLDDKGRRMVGK
                     VCVLGSFNVDIVAKVYRFPNEGETLVARETTMGPGGKGANQALAAHRAGAQIHFACKI
                     GRDQFNHFARNHIESIGIGSFTFYESELSTTGCAVIYVNDEGENMIAMSPGANHELSD
                     NDIIQLSHFIAESDVFIVQMENNLAATQLALKCAQKMQVTTILNPAPWSSDVATLLPF
                     VDIVTPNETEASAMSGMVIDNISDAVKAAKHIYNAGQCSVIITMGKRGALIYDGQQCA
                     HIPAFSAVAVDTTGAGDAFNGALAAALAKGESLVKAAWYASAFASLAVEKEGAANMPD
                     ISLVDARIQQQNVAIQTF"
     gene            1264..2187
                     /locus_tag="LSX49_003923"
     CDS             1264..2187
                     /locus_tag="LSX49_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBL7170266.1"
                     /translation="MKTIEGIIPVMLTPFTADNKIDYLGLKRLIDWYIENGADALFAV
                     CQSSEMQYLTLEERVELASFVVEYSQQRVPVIASGHISDDLEQQIQELNAMAATGIDA
                     LVLVTNHLDPHNEGTTVFLRTLDALLMSLPESMALGLYECPAPYRRLLTDEELLYCAQ
                     SGRFQILKDVSCDLPTVTRRVQLTQHTPMTIVNANAAIAWEAMLAGSKGFCGVFANFH
                     PDLYHWLWLEGKQHPEEAKQLAWFLSLSAVSENIGYPKNAKIFHQQRGTFDCVHCRVT
                     ADDVLKKYWGLEVVLKQIADAADFQRQQLKY"
     gene            2242..3195
                     /locus_tag="LSX49_003924"
     CDS             2242..3195
                     /locus_tag="LSX49_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HBL7170267.1"
                     /translation="MKRTLMSCAVASLLVSGSALAAWPEKPIQIIVPWGAGGNTDTVA
                     RLVAEGLQKELKVNVNVVNRTGGAGVVGHDAIAKAKADGYTLGIATVEITMMHHQGMT
                     ALTYQNYTPITRLAVNLGGVQVAANSQFENIVQMTDYIKANPGKLKASGSGLNSGWHL
                     NLIGMLDSMGLPPSAVTWVPSEGSSSALMELVSGGIDFTTSSPGEAKSMVDAKMVRNL
                     ATMAEKSAGLYKDLPVFQQATGYKYHLATWNALVVPAGTPEEVSQKLTAAMQAVFAQG
                     KLQEFATKQGFEVYPLYGKEMTTFMADEDARYGKLIAKIKG"
     gene            3244..3681
                     /locus_tag="LSX49_003925"
     CDS             3244..3681
                     /locus_tag="LSX49_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HBL7170268.1"
                     /translation="MRIIPITPLFLLIFAMFIFGWSITQYGGISQYGAGFMPCIISGL
                     LLFLAAIDVAIDIKHRHRNKVSLTFDEVKALLLVITVVLLFVLLLDILGFVICSFLLL
                     FILMKIRGVRLLHSVIVSISASLIIWFIFARVLLVAFPEGILF"
     gene            3691..5178
                     /locus_tag="LSX49_003926"
     CDS             3691..5178
                     /locus_tag="LSX49_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000350780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HBL7170269.1"
                     /translation="MDILIQALTYINLNAILAIIAATAFGLFVGAIPGLTATMAVALM
                     VPFTFFLDPIPALALMIAVGASSIYAGDIPGALLRIPGTPASAAYVADSNELVKQGKV
                     NRVLGLGLVSSVIGGVIGSLILMLAAPVLAKFALNFSSYEYTWLSLLGLTCATLVVGN
                     QPLKGMVTLCLGLLLACIGYDQISGVPRFTFGQISLLQGVNFIPAMIGLFAISGAIEY
                     YRDKISQVSGVVPQTQTGINLFKGMGQVIWSRKLNLGRSSIIGTLIGALPGAGADIAA
                     WISYAISKKFSRQQELYGHGSEEAIVDSSSSNNASLAGSWIPSLVFGIPGDSAAAIII
                     GVLYMKDMNPGPTLFLFQADKLYAVFILFLIANIALLPLATIAVSFIKRIIWIDKAIL
                     YPIILIFSIVGAFAIDNSGASVVVMLVMGVLGYWLQRKEYPVSPIILGMILGPMLEKN
                     LLSSMIKSNGEWLAFVERPVSMALAVCFFLVVALQGRNIYRSFSR"
     gene            5362..6126
                     /locus_tag="LSX49_003927"
     CDS             5362..6126
                     /locus_tag="LSX49_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBL7170270.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLVTAVLLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     gene            complement(6240..6938)
                     /gene="thiQ"
                     /locus_tag="LSX49_003928"
     CDS             complement(6240..6938)
                     /gene="thiQ"
                     /locus_tag="LSX49_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HBL7170271.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGLLTLDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAAQQKKMHAIAHQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSSSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTDELL
                     SGKASASALLGIKG"
     gene            complement(6922..8532)
                     /gene="thiP"
                     /locus_tag="LSX49_003929"
     CDS             complement(6922..8532)
                     /gene="thiP"
                     /locus_tag="LSX49_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HBL7170272.1"
                     /translation="MATRRQPLIPGWLIPGISAATLVVAVALAAFLALWWNAPQGDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRQVLLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLWQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTALIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKIPGRNVKTD"
     gene            complement(8508..9491)
                     /gene="thiB"
                     /locus_tag="LSX49_003930"
     CDS             complement(8508..9491)
                     /gene="thiB"
                     /locus_tag="LSX49_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HBL7170273.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     TEAVNVPGGWKNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYEDPRT
                     STPGLGLLLWMQKVYGDNAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     regulatory      complement(9522..9621)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(9655..11310)
                     /gene="sgrR"
                     /locus_tag="LSX49_003931"
     CDS             complement(9655..11310)
                     /gene="sgrR"
                     /locus_tag="LSX49_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SgrR"
                     /protein_id="HBL7170274.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQETTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLTEIADEPAGGLMLKGPQGEEQEIESRLEEG
                     CYYLLFDNRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARP
                     THCEKPAGLEHLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIES
                     DIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     gene            11399..11530
                     /gene="sgrT"
                     /locus_tag="LSX49_003932"
     CDS             11399..11530
                     /gene="sgrT"
                     /locus_tag="LSX49_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HBL7170275.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY"
     gene            complement(11637..12242)
                     /gene="leuD"
                     /locus_tag="LSX49_003933"
     CDS             complement(11637..12242)
                     /gene="leuD"
                     /locus_tag="LSX49_003933"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBL7170276.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR"
     gene            complement(12253..13653)
                     /gene="leuC"
                     /locus_tag="LSX49_003934"
     CDS             complement(12253..13653)
                     /gene="leuC"
                     /locus_tag="LSX49_003934"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBL7170277.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     gene            complement(13656..14747)
                     /gene="leuB"
                     /locus_tag="LSX49_003935"
     CDS             complement(13656..14747)
                     /gene="leuB"
                     /locus_tag="LSX49_003935"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBL7170278.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            complement(14747..16318)
                     /gene="leuA"
                     /locus_tag="LSX49_003936"
     CDS             complement(14747..16318)
                     /gene="leuA"
                     /locus_tag="LSX49_003936"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBL7170279.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIDKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            complement(16410..16496)
                     /gene="leuL"
                     /locus_tag="LSX49_003937"
     CDS             complement(16410..16496)
                     /gene="leuL"
                     /locus_tag="LSX49_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HBL7170280.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
BASE COUNT         3930 a         4177 c         4453 g         4308 t
ORIGIN      
        1 gacttatgta tcgggatacc cgtcgtgaat atattgtccg gttacttcgc aacaaggatg
       61 agtgcagtgt tagcgattta gctaactatt tttctgttac caaagagacg attcggacag
      121 atttagcgtg gttgcaaaag cgtggtgtag tgagtcgtca tcatggaggc gtctcattga
      181 aaaaacattt aatgcaaaat gcgctttcgc aacaagagta tgtcgatatg agtttgctta
      241 tcaagcaaca acagcagggt attggctatt taacctcgct tgatgataaa ggacgccgaa
      301 tggtaggtaa agtttgtgtg ttaggatcat ttaacgtcga tattgtggcg aaagtgtatc
      361 gcttcccgaa tgaaggcgaa acgttagtgg ccagggaaac taccatgggg ccggggggta
      421 aaggcgcgaa tcaggcacta gccgctcatc gggcaggtgc gcaaatacac ttcgcctgta
      481 agattggtcg cgatcagttt aatcattttg cccgcaatca tattgagtcc attggtattg
      541 gttcatttac tttttatgag tctgaactat ctaccaccgg ttgtgcggtc atttatgtaa
      601 atgatgaagg tgaaaacatg attgctatgt ctccaggggc aaatcatgaa ttaagtgata
      661 acgatattat tcaactttct cactttatag ccgagtccga tgtattcatt gtacagatgg
      721 aaaataatct tgccgctact caactggcat taaaatgtgc tcaaaaaatg caggtgacaa
      781 cgattttaaa tcctgcaccg tggtccagtg atgtcgccac attattacct tttgttgata
      841 ttgtgacgcc aaatgaaacc gaagcatcgg cgatgtcagg tatggtaatt gacaatattt
      901 ctgatgctgt gaaggctgcg aagcatattt ataatgccgg gcaatgttca gtaattatta
      961 cgatgggaaa acgaggtgca ttaatttatg acgggcaaca atgtgcgcat attccggcat
     1021 tttcggcagt cgctgtagat acaacaggtg cgggtgatgc gtttaatggc gcgctcgccg
     1081 ccgcactggc gaagggagaa tcacttgtta aagcagcctg gtatgccagc gctttcgctt
     1141 cgctggcagt agaaaaagaa ggggcagcca atatgcctga tatctctctg gtggatgcca
     1201 gaattcagca gcagaatgtt gccattcaga ctttctgatg tttcactgaa cgaaggatga
     1261 aatatgaaaa caattgaagg gattattccg gtaatgctaa cgccttttac ggcggataat
     1321 aaaattgatt acctgggtct taaacggcta attgactggt atatcgaaaa cggtgccgac
     1381 gcgttatttg ccgtgtgtca gtccagtgaa atgcagtatt taactttaga agagcgcgtg
     1441 gagctggcga gctttgtggt tgaatatagc caacaacgag taccggttat tgcgtccggg
     1501 catatttctg atgatctgga acagcaaatt caggagctca atgctatggc ggcaacgggc
     1561 attgatgcgc tggtgttagt gacgaatcat cttgatccac ataacgaagg taccacggta
     1621 ttcctccgta cgcttgatgc gctattgatg tcattacccg aaagtatggc gctgggtctg
     1681 tatgaatgcc cggccccgta tcgccgctta ttaaccgatg aggaactgct ttactgcgca
     1741 caaagcgggc gttttcaaat cttaaaagac gtcagttgtg atctacctac agtgacgcga
     1801 cgggtgcaat taactcagca cacgccaatg acgattgtta atgctaatgc tgccattgcc
     1861 tgggaggcga tgcttgcagg ttcgaaaggt ttttgtggcg tctttgccaa ctttcatcct
     1921 gacttgtatc actggctttg gcttgaagga aaacaacacc ctgaagaggc aaaacaactc
     1981 gcctggtttt tatcgctgag tgccgtcagt gaaaatattg gctatccgaa aaatgccaaa
     2041 atatttcatc agcagcgagg aacatttgac tgtgttcatt gccgggtaac ggctgacgat
     2101 gtgctgaaaa aatattgggg gctggaggtg gtgctaaaac aaattgctga tgccgcagat
     2161 ttccagcgtc aacaactcaa atattaatat ccgacagcac ttgctgttat taaaaaataa
     2221 ttaagacagg agtctacaaa tatgaaacga accctgatga gttgtgccgt tgcttcactg
     2281 ctggtttcag gttccgcgct ggctgcatgg ccagaaaaac caatccaaat cattgtcccc
     2341 tggggcgcgg gaggaaatac cgatacggtt gcacgcctgg tggcagaagg gctgcaaaaa
     2401 gagttgaaag tgaatgtcaa cgtggtgaat cgcacgggag gtgctggggt ggttggccat
     2461 gatgccattg cgaaagctaa agcggatggc tataccctgg gaattgcgac ggtagaaatc
     2521 accatgatgc accatcaggg gatgacggcg ttaacgtatc agaactacac gccaattaca
     2581 cggctggcag tgaatctggg aggcgtgcaa gtcgcagcaa attcgcagtt cgaaaatatc
     2641 gtccagatga ccgactacat caaggcgaat ccaggtaagt taaaagcatc gggtagcggg
     2701 ttaaattccg gctggcatct gaacttgata ggtatgctcg acagtatggg gcttccgcct
     2761 tctgccgtga cctgggtgcc ttctgaaggt tccagttctg cactgatgga actggtttcc
     2821 ggtggtatag attttacaac gtcatcacca ggcgaagcga aaagtatggt cgatgccaaa
     2881 atggtgcgta atttagcgac catggcagaa aaatcagcag ggctttataa agatcttcca
     2941 gtattccaac aagcaactgg ctataaatat catttggcga catggaatgc cttagtggtt
     3001 ccggcgggta ctcctgaaga ggtctcacaa aaattaactg ccgctatgca ggcagtgttt
     3061 gcgcagggga aattacaaga attcgctacc aaacagggtt tcgaagttta cccgctgtat
     3121 ggcaaagaga tgacgacatt tatggcagat gaagatgcca gatacggaaa attaatagcc
     3181 aaaatcaaag gttaatcaga cagggcggtg aatatatcgc cgccaaatta cagggatagc
     3241 attatgcgca taataccgat aacgccgtta tttctgctga tttttgccat gtttattttt
     3301 ggctggagca taacgcaata tggaggcata tcgcagtatg gcgctggatt tatgccttgc
     3361 atcatcagtg gattgttgtt gtttttagcg gctattgatg tagcgataga tattaaacac
     3421 cggcaccgta acaaagtttc tttaactttt gatgaagtga aagcactttt actggttatt
     3481 acagtggtac tactgtttgt attactgtta gatattctcg gctttgtgat ttgctcattt
     3541 ttgttgcttt ttattttaat gaaaatacga ggtgtcagac ttttgcattc cgttatcgtt
     3601 tcgatatcgg catctcttat tatctggttc atttttgcca gagtgttgtt ggtcgccttt
     3661 cctgaaggaa tcttgtttta aggatgcaat atggatattt tgattcaggc actaacgtat
     3721 attaatttga atgccattct ggccattatt gctgctacgg cctttgggtt atttgtgggg
     3781 gccatccctg gattgaccgc aacgatggcg gttgcactaa tggtgccttt taccttcttt
     3841 cttgatccta ttcccgccct ggcattaatg attgccgttg gtgcgtcatc catttatgcc
     3901 ggagatatcc ccggcgcact tttgcgtata ccagggacac ctgcttcggc ggcttatgtt
     3961 gctgattcaa atgaactggt caagcaaggg aaggtgaatc gcgtattggg acttgggctg
     4021 gtgagttcgg tcattggtgg cgtgattgga tcacttattt tgatgttggc tgcgcctgta
     4081 ctggcgaaat ttgcccttaa ttttagttct tatgaataca catggctttc tcttttaggc
     4141 ttaacttgcg cgactctggt tgtgggtaat caaccactga aaggcatggt gaccttatgt
     4201 ttgggattat tactggcgtg tatcggttat gatcaaatat ccggagttcc acgttttacg
     4261 tttggtcaaa tcagcctgtt acaaggggtg aactttatcc cggcgatgat tggtctgttc
     4321 gcgatatccg gcgcaattga atattatcgt gacaaaatta gccaggtaag tggtgttgtg
     4381 ccacaaacgc aaacggggat taatttattc aagggaatgg ggcaggtgat ttggtcacga
     4441 aaattaaatc ttggccgaag tagtattatc ggtacgctta tcggagcatt acccggcgct
     4501 ggagcggata ttgctgcgtg gataagttac gccatttcaa aaaaattctc tcgccagcag
     4561 gagttatatg ggcatggatc tgaggaggca attgttgatt cctcgagcag taacaacgcc
     4621 agtctggcgg ggagttggat cccttcatta gttttcggta ttccgggcga ttctgccgct
     4681 gcaattatca tcggcgtgct ctatatgaag gatatgaatc cagggccgac attatttctg
     4741 ttccaggcag ataaacttta tgccgtattt atcttgtttc tgatcgccaa tattgcatta
     4801 ctaccgttag ccacaattgc ggtcagtttc atcaaacgca tcatctggat tgataaagcg
     4861 attctgtacc cgattattct gattttcagt attgtcggtg catttgctat cgataactcg
     4921 ggtgcttctg tcgttgtcat gttggtcatg ggggttcttg gatactggtt acaacgtaag
     4981 gaatacccgg tttcgcccat tattctgggg atgattcttg ggccaatgtt ggaaaaaaac
     5041 ttattatctt caatgattaa gtctaatggc gaatggctgg cgtttgttga gcgcccggta
     5101 tctatggcac tggctgtctg tttctttttg gttgtcgcgt tgcaaggacg caatatctac
     5161 cgttcattta gccgttaatc cgttgttttc agaccatcca agttgtggat ggtctgcctt
     5221 cccctaagta aaatcctgcg tgactgctaa atttatactc taaatgattc gcgttgcagg
     5281 aatatattca tacaaagaat agattgacct gaataccacc actttgcaca atccacgacg
     5341 aattcatcaa ccgggcacat tatgcaagca ttgctggaac actttattac ccaatccacc
     5401 gtgtattcat tgatggcggt ggtgttggtg gcctttctgg agtcgctggc gctggtcggt
     5461 ttgattctgc ccggtacggt gctgatggcg gggctgggag cgttgattgg cagcggtgag
     5521 ttaagtttct ggcacgcctg gctggcaggg atcgtcggtt gcctgctggg cgactggatc
     5581 tccttctggc tgggctggcg ttttaaaaag ccgttgcatc gctggtcatt tctgaagaag
     5641 aacaaagcat tactcgataa aaccgaacat gcgctgcatc agcacagcat gttcaccatt
     5701 ctggtcggtc gttttgtcgg cccgacgcgt ccgctggtgc caatggtggc agggatgctg
     5761 gatctgccgg tggcgaaatt tattacgcca aatattatcg gctgcctgtt atggccaccg
     5821 ttttacttcc tgccggggat tctggcgggt gcggcgatcg atattcctgc cgggatgcag
     5881 agcggtgagt ttaaatggtt gctgctggtg acggcggtat tgttgtgggt tggtggctgg
     5941 ctgtgctggc ggttatggcg cagcggtaaa gcgactgacc gtttgagtca ttatttgtcc
     6001 cgcggtcgtt tgttgtggct gacgccgttg atttctgcca tcggcgtggt ggcgctggtg
     6061 gtgttaattc gccacccgtt gatgccggtg tatatcgata ttttgcgtaa agtggttggg
     6121 gtttagagga tagccttgtg cgggttgcct gatgcgacgc ttgctgcgtc ttatcaggcc
     6181 tacaaaacgc actacctgta ggtcggataa ggcgttcacg ccgcatccga cagtgcatat
     6241 taacctttaa ttcccaacag cgccgaagca ctcgccttac cgctcaacaa ctcatcggtc
     6301 ttaccctgcc aggcgatacg cccgtcggcg accaccaccg agcgcgtggc gatccgcgcc
     6361 gcatcttcca cactgtgcga caccatcaag agcgtcattt tttgctgttg gcagctcgaa
     6421 ctcaccagcg tcagcatctc ctgacgtagc gccggatcga gtgcggaaaa cggttcatcg
     6481 agcaataaaa tgggctgttc gcgtaccaga caacgcgcta acgccacgcg ctgtcgctga
     6541 ccgccggaaa gctcgccagg taaccgcgcc attaaattat caatccccat ctggtgggca
     6601 atcgcgtgca ttttcttctg ctgcgccgca tttagtttca accccggatt tagccccagc
     6661 ccgatgttct gcgcgaccgt caggtggctg aacaggttgt tctcctgaaa cagcattgac
     6721 accggacgac gtgacggtgg cgttgtggtg tgatctacgc cgtcgagagt cagcaaaccg
     6781 ctggctggcg tcagaaaacc ggcgatcaaa tttagcaggg tgcttttacc cgcgccgctt
     6841 ggcccgagga tcgccacctg ctcgccgcgt tccaccgtta agctaaaacg catcggcaaa
     6901 tggtggtaaa gccaggtgat atcagtcagt tttaacattt cgccccggta ttttttcaat
     6961 cacggtaaac agcagaaaac agagcagcag cagaattaac gcggtgaccg cgccgtcctg
     7021 gctgcgatag gagccaattt gctgatagag ataaaacggc agggtacgga aatcatcgtt
     7081 accgaacaat gccaccacgc caaaatcacc aatcgacagc acacaagcaa aggccagcgc
     7141 ctgcgccagt ggacgtttca gagcgcgcag ctccaccact tttaagcgtg accagccttc
     7201 aatgcccagc gactgacaca acatgctgta gcgggcggtg atatcgcgca tcgggttttc
     7261 cagtactttc agcgcataag ggattgccat taacgcattg gtgaaaatca caatgccgtc
     7321 agcagattgt ggcaggccga tagtgttgtt gagcagtaaa aagaagcccg tagccagtac
     7381 aatccccggc atggcgagga tcaacatgcc gctcatctcc agcgcctgac ccgccagcat
     7441 tttctgccgt gcccgaagtt cgcgactgct ccatagcagc atcatggtca gcactacgca
     7501 caatacgcct gccgccagcg caatacgcaa cgaggtccac agcgcctgcc acagcaccgg
     7561 ttgtgccagc acttccggca actggcgatt taccccatcg acgatcaccg ccagtaacgg
     7621 tggcagcaac agcagcagcg ccagcacaat taacgccgtg tcgcaaatgc gactatgcag
     7681 acgatcgtcc gggtcgcgcc agccttgcag cagtgtggta ccgggcgcaa tggccttact
     7741 caatcgctga ctcaacagca ccagcccgag gcagcacacc atctggatca gcgccagcat
     7801 tgccgcgcgg gcaggatcgt agtcgtaact cagcgcctga tagattgcca gctcgatagt
     7861 ggtcgcctgc ggaccgccgc ccagcgatag cacggtggcg aagctggcga aacagagcat
     7921 aaagataagc gcagcaaccg gcgggatttg tcgccgtaac cacggccatt cgacgaagcg
     7981 gaagaagtgc cagccgcgca tcccaagttg tgcggcaagc tgacgttgtt cgccgggaat
     8041 gttttccagt gcctggagta ataaacggct agccatcggc agattaaaaa acacatgggc
     8101 cagcaaaatg ccttgcaggc cgtagggcga aaaggtccac tccagaccaa gtgattgcca
     8161 gagcgaggcc agccagccct ggcgaccata gacgctaaga atgccgaaaa cggcgaccag
     8221 caccgggagg atcaaggtca ttgcgcacag acgcaacagc acctgtcgcc caggaaagcg
     8281 cctgcgatag agcgcgcggg cgaggaatat tgcgggtacg acagagagca gcgccgagag
     8341 aaacgcctgc cagaaggaga agcgcaccac atgccacaga tagctgtcct gccagactgc
     8401 cacccagtca ccctgcggcg cgttccacca cagggcgaga aacgccgcca gcgcaaccgc
     8461 taccaccagt gtggcggcgc ttattcctgg aattaaccag ccgggaatta acggctgacg
     8521 gcgcgttgcc attcgctaat ccatgcctga cgttgtgccg ccacttcggc gggcgtgaac
     8581 tctagcgtgg tggctggttt ggtcaattgt tcaaatcctg caggcagagt gacgtttgct
     8641 accggataca tccagttgcc ggttgggatc gcattctgaa aagccggaga aaccataaac
     8701 tggaggaatt tttgcgccag ctctggctgc ttgctggcag cggtgcgggc ggcaacttcc
     8761 acctgcagat agtgaccttc gctgaagttc gcggcggcgt agttatcttt cttctcttcg
     8821 agaatgtgat aagccggaga ggtggtgtaa ctcagtacca gatcgctttc gccttttaaa
     8881 aacaggccgt aggcttcgct ccagccttta gtgaccgtga cagttttctt cgccagtttc
     8941 tgccaggctt gcggggcgtt atcgccatag actttttgca tccatagcaa cagacccaga
     9001 cctggtgtac tggtacgcgg atcttcataa atcacccgcc agttttgatc gctctcaacc
     9061 agttctttca ggctttgcgg cggatttttc agtttgttct tgtcatagac gaaggcgaaa
     9121 tagccatagt caaacggcac aaaggtgtca tttttccagc cgccgggaac gtttacagcc
     9181 tctgtcgcga cgccgctttt ggcaaacaac ccggttttgc tggcggcgtc cagcaggttg
     9241 ttatccagcc ccagcaccac atcggctttg ctgtttttgc cttccatccg tagacggttg
     9301 agcagcgaaa cgccatcttc cagcgccacc agtttcagtt cgcaattaca gtctgcttca
     9361 aaggcttttt tgactaccgg accaggtccc cagtcagcgg caaaggaatc gtaggtataa
     9421 acagtcagaa caggtttagc gaaaacaggc gctgtgcaca gcaacagcag gggaagacat
     9481 ttttttaaca ctttgcacct cacaaaagag tggcaaagga cttgagaagg agcctcaaat
     9541 cccttcgccg gcgttatccg gatcaggttc gacgggtatt ttctcagcgc acgcggctgc
     9601 gtggcacccc gttgagaacg gcgttagtgt agtgattttg ttatcaacca gcaatcatgg
     9661 atccggtggt gcaaaccacg ctgatttaaa atcgaaccag ccgagggtgt tcatgcgcag
     9721 gccgcgcata ctgcgttgcc cctgaatgat cagccagtgg tggataagtg gcaccattgc
     9781 tttgctggcg accagttgct ggcaccagtt cgccaggttc atttcgccat tgcgccagcg
     9841 ggcggcgtcg gcttgccagt cgatcggaat acagtgttgg agtagcggca cctcgcacaa
     9901 gtgcgcgaac agcgaaaaat ccagcggcag cgtaaagttg gcgctgttaa gccagatatc
     9961 gctctcgatc tctccttcat gccactgatc gtagctgatc tctttgattt ccagcgtgac
    10021 ctggtgactc gccagaatct gctgcatgat cccggcaatc actcgatgtt caatatgatc
    10081 ctgataaaag gtcagggtga gatgttccag cccggcgggt ttttcgcaat gtgtcgggcg
    10141 ggcatggtgc cagcggggga gcagtccata agccgggaac cagagttgct ggtattgttc
    10201 ctcggcgaaa tagaccagat tcgtcggaga aagcacatag cttacccagt ccctgacttg
    10261 ctgattcgcc ccgcggtggg tgcggttgtc gaacagtaaa taatagcaac cttcctccag
    10321 gcggctttca atctcttgtt cctcgccctg cggccctttc agcatcagcc ctccggctgg
    10381 ctcgtcggca atttccgtta gaacccagac gttaacttcg tcgattaatg cccggtaacc
    10441 gaagaagtca tcgaatgcct gaattttcag ttgattggtg ctgttgcgga tcaccgcata
    10501 cggaccggtg ccgatgggat ggctggcaaa gttactgagg gtttcccatt cgcgcggcag
    10561 gatcattgcc ggaacttgcc ccagcagtaa cggcaaccag cggtccggtt gcgtgagatg
    10621 gatatccagc gtccagggcg tcggcgacac aatgtcagca atatgcgaat agagcggaag
    10681 cgtattgatt cgttttaaag aggcgatcac atcgtccatt tccagttcac gaccatggtg
    10741 aaaatggact cctggacgca aaaagaaacg ccagtgaagc ggtgatattt gctgccagtg
    10801 gtgtgcgatg tctgcttcca gttccccatt ttcctcattt atgcgcgtta gcgaactgaa
    10861 gatttgccgg gcgatatggg tttcagaacg gcgcaatgcg ctgccaggta gcagattacg
    10921 caacggacga tagtagagca cgcgcaggat gtgccgcccc tggcggaagc tgcggcccag
    10981 atgagaaacc agcatttgcc gcacagtcgc tttgtcgcca accaactgca ctagttggtc
    11041 gatacgatcc tgctccagca ggtcttccgc tcgctgttgc tgaagcgcca gcccggtata
    11101 gaggaatgtc agacgcgagc gtttaccgcg cccgacttcc gcttcccacg tcagccagcc
    11161 gcgatcctgc atggtgttga gcagggtgcg catatgacga cgcgagcaac tcagtaacgc
    11221 tgccagttcg ttgagcgtgg tctcctgaga tttaccctcg cagcattgcc acaggcggat
    11281 gaactgttgt tgcagacgag cagatggcat aaaaggggaa ctcctgcgca aaagacagca
    11341 attttatttt ccctatatta agtcaataat tcctaacgat gaagcaagga ggtgccccat
    11401 gcgtcagttt tatcagcact attttaccgc gacagcgaag ttgtgctggt tgcgttggtt
    11461 aagcgtccca caacgattaa ccatgcttga agaactgatg caatgggagg ggagtcattc
    11521 tgactactga tttgcggaca tcatgtgtga ctgagtattg gtgttaatcg ccacgccagc
    11581 agtgattatc tgctggcttt tttcttttgg cgattgagtg ccggacggtg tacaaactaa
    11641 cgcataaacg ccggttgctt ctcttcataa gacgcaatag catcgtcgtg ctgcagagtc
    11701 aggccgatgc tgtccagacc gttcatcatg cagtggcggc ggaaggcatc gatggtaaag
    11761 cgataagttt tctctcccgc tttcacctct tgcgcttcca ggtctacatc aaaatgaatc
    11821 cccggattgg ctttcaccag cgcaaacagc tcatccactt ctgcatcgct taatttcacc
    11881 ggcagcagct ggttgttaaa gctattgccg tagaagatgt cagcaaaact cggcgcaatc
    11941 accaccttaa aaccgtaatc ggtcaatgcc cacggcgcgt gctcacgcga ggaaccgcag
    12001 ccgaagtttt ctcgtgccag caaaatggaa gcgccctgat actgcgggaa gttcagcacg
    12061 aagtccgggt ttggctgttg gcctttttca tccagaaaac gccagtcgtt aaacagatgc
    12121 gcgccaaaac ccgtacgggt cactttctgc aaaaactgtt tcgggatgat tgcatcggta
    12181 tcgacattgg cggcatccaa cggaaccacc aggcctgtgt gtttgataaa tttctctgcc
    12241 atggtgtgct ccttatttaa tgttacgaat gtcggcgaaa tgtccggtca cagccgcggc
    12301 ggcagccatt gccgggctga ccagatgcgt gcgcccgccg cgcccctggc ggccttcaaa
    12361 gttacggttg ctggtggagg cgcaacgttc gcccggattc agacggtcgt tattcatcgc
    12421 cagacacatt gagcaacctg gcaagcgcca ttcaaaacca gcttcgataa aaattttgtc
    12481 cagaccttcc gcttccgcct gggctttaac cggaccggag ccgggaacca ccagcgcttg
    12541 tacgcctggc gcgactttcc ggcctttggc gatttccgct gccgcgcgta aatcttcaat
    12601 acgcgagtta gtacaggaac caataaacac tttgtcgata gccacttctg tcagcggaat
    12661 acccggtttc agccccatat aggccagcgc tttttctgcc gacgcgcgtt caaccggatc
    12721 ggcaaacgaa gccggatcgg gaatattgtc gttcacagaa atcacctggc ctggattggt
    12781 gccccaggtg acctgcggcg aaatctcttc tgcttgcaga gtgacaacgg tatcgaaagt
    12841 tgctccttcg tcggtttgca gggttttcca gtaggcaacg gcgtcgtcga aatctttacc
    12901 tttcggcgca tgcagacggc ctttaacata gttaaaggtg gtttcgtccg gcgcaaccag
    12961 accggctttt gcgcccattt cgattgccat attgcacagg gtcatacgac cttccatgct
    13021 taaatcacgg attgcttcgc cgcaaaattc caccacatgc ccggtaccgc ctgcgctgcc
    13081 ggttttacca ataattgcca gcacgatatc ttttgcggta atgcccggcg cggctttgcc
    13141 ctggacttca attttcatgg tcttcgcccg gccctgtttc agggtttgcg ttgccagtac
    13201 gtgttcaact tcggaagtgc cgataccaaa ggccagtgcg ccaaacgcgc cgtgggtggc
    13261 ggtatgtgag tcgccgcaga caatggtcat ccccggcaag gtcacaccct gttccggccc
    13321 cattacgtgg acgatcccct gatacgggtg attcaggtca tacagctcga cgccaaattc
    13381 tttgcagttt ttgatcagct cctgcatctg gatgcgcgcc atttcaccgc aggcattaat
    13441 gtctttcgtc tgggtagaga cgttgtgatc catggtggcg aaggttttgc ccggctgacg
    13501 taccgggcga ccgtgggcgc gcagaccatc gaacgcctgc ggtgaggtca cttcatgcac
    13561 caggtggcgg tcgatatata acagcggggt ttcgttttcg gcttcgtaca ctacgtgagc
    13621 gtcgaataat ttttcgtata acgtcttagc catgattaca ccccttctgc cacatagcgg
    13681 gcaatgatat cgcccatttc atcggtacta acggcggcag cgccacgggc taaatccccg
    13741 gtgcgaatgc cttcttctaa tgcgcggtta atggcgcgtt caatggcgga agccgcatca
    13801 tcggcatcca ggctgtaacg cagcagcagc gccagcgaca gaatttgtgc aatcgggttg
    13861 gcgatatttt tacctgcgat atcgggtgcc gagccgcccg ccggttcata cagaccaaaa
    13921 ccttgctcgt tcaggctggc ggaaggcaac atccccattg agccagtgat cattgcgcac
    13981 tcatcagaca gaatgtcgcc aaacaggttg gagcacagca agacgtcaaa ctgtgatgga
    14041 tctttaatca gctgcatggt ggcgttgtcg atgtacatat gcgccagttc gacgtccggg
    14101 tattccgtgg cgatctcgtt aacgatctcc cgccataaaa tagaggattg cagcacgttg
    14161 gctttgtcga ttgaggtgac tttgtggcga cgcttgcggg cagattcaaa tgcgatgcgg
    14221 gcaatacgct cgatctcaaa acggtggtac acctcggtat caaacgcttt ttcatattgt
    14281 ccgctacctt cgcggccttt tggctgaccg aaatagatgc cgccggtcag ttcgcgcaca
    14341 cacaggatgt caaagccgtt tgcggcaatg tcagcacgca gcggacagaa tgcttccagc
    14401 ccctgataca gttttgccgg acgcagattg ctgaataatt tgaagtgctt acgcaaaggc
    14461 agcagtgcgc cgcgttctgg ttgctggtct ggcggcaaat gttcccactt cggaccacct
    14521 accgagccaa acagcacggc atcggcttgc tcacaacctt caaccgtcgc aggcggcagc
    14581 ggctgcccgt gattatcaat ggctgcgccg cctacatcgt aatggctggt ggtgatacgc
    14641 atcgcaaatc ggttgcgcac ggcatccagc actttcagcg cctgggtcat cacttccgga
    14701 ccaataccgt cccccggcaa tacggcaata tggtaattct tcgacatcac acggtttcct
    14761 tgttgttttc gttgtgttga gctttgcgtt gcaactcttt ttcgacttct gcggcacgcc
    14821 agatattgtt cagtacgtgc accatggctt tggcggagga ctcgacaata tcggtggcca
    14881 ggccgacgcc gtggaagcgg cgaccgttgt agttggcgac aatatccacc tgacccagcg
    14941 catctttacc gtgacctttg gcggtcaggc tgtatttcac cagttcgacg ttatagtcag
    15001 tgatgcggtt tatcgcctgg tagacggcat caaccgggcc gttgccgtta gcggcttctg
    15061 ctttaacttc ttcgccacag gccagtttga cggcggcagt ggcaatatcg ttagaacctg
    15121 actgcacgct gaagtaatcc agacggaaat gctccggctc ttcttgctgc ttatcgatga
    15181 aggccagcgc ctccagatcg taatcaaaca cctggccttt tttgtccgcc agcttcagga
    15241 aagcgtcgta caggttgtct aaattatatt cactttcttt atatcccatc tcatccatgc
    15301 gatgtttcac cgccgcacgc cccgaacgag aggtcagatt cagctggatt tggttcagac
    15361 caatagattc tggtgtcatg atttcgtagt tttcgcggtt tttcagtaca ccatcctggt
    15421 ggataccgga ggagtgtgcg aatgcgccgc tgccaacaat ggctttgttt gccgggatcg
    15481 gcatattaca aatctggcta actaactggc tggtgcgcca tatctcctgg tgattgatgg
    15541 cggtgtggac gttgagaata tccttacgaa ctttgatcgc catgatgact tcttcaaggg
    15601 aacagttacc ggcacgctcg ccgatcccgt tcattgcgcc ttctacctgc cgtgctccgg
    15661 catgtaccgc cgccagtgag ttgccgaccg ccaggcccaa atcgtcgtgg gtatgtacgg
    15721 aaataatggc tttgtcgatg ttgggtacgc gttcatacag gccgctgatg attccggcga
    15781 actcaaatgg catggtgtag cccacggtgt ccggaatgtt gatggtggtg gcaccggcat
    15841 taatcgccgc ttcgaccact cgcgccagat cggcaattgg ggtgcgtccg gcatcttcgc
    15901 aagaaaattc aacatcatcg gtgtaattac gggcgcgttt caccatatag atagcgcgtt
    15961 cgatcacttc gtccagcgtg ctgcgcagct tggtggcgat gtgcattggc gaagtggcaa
    16021 taaaggtatg aatacggaag gcttcggcga ctttcaggga ttcggctgcc acgtcgatat
    16081 ctttctccac gcagcgagct aacgcgcata cacggctgtt tttaacctgg cgagcgatgg
    16141 tctgcactga ttcaaaatca cccggcgaag agacggggaa accgacttcc atcacgtcaa
    16201 cacccatacg ctcaagggcc agcgcaattt gcagtttttc tttcacactc aagcttgcct
    16261 gtaacgcctg ttcaccgtcg cgcaatgtgg tatcgaaaat aatgacttgc tggctcatgg
    16321 tttgggtcct tgtctctttt tgagcgcctc gcttcgggca taaaaaaacc cgcgcaatgg
    16381 cgcgggtttt tgtttgactg cgtgctggct taatgctgga tgccgctcac tcgtctaccg
    16441 cgcaaagaag atgcgtttag tagtagtaga ccgataaagc gaacgatgtg agtcattaaa
    16501 tcagctccag atgaatgcga tatgctttta gagttactgg atacaaaaac ggatgtcaac
    16561 cctgaagcaa taaaaacgtc acgccattgt gagttcggca tccgtaaaat tagctaattg
    16621 tgctgcggtg gttaaaacaa gcgatattaa tttctgctta accgccgatg cttttcatcg
    16681 gttgacatat ttcagaataa ttttttgcat ctaatcaacg agggaaaggg ggataaaatg
    16741 cacgcgttac aaaacctatc ctgatgattt gtattgaatt atatgttttg cgaatttttt
    16801 gatattcatt tggtgaatat tattgatcaa ttaatgttaa gaattaatgc attaaacata
    16861 taaattaa
//
LOCUS       DAFGPF010000108        16776 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFGPF010000108 DAFGPF010000000
VERSION     DAFGPF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16776
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.108"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(208..333)
                     /locus_tag="LSX49_003938"
                     /pseudo
     CDS             complement(208..333)
                     /locus_tag="LSX49_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
     gene            375..605
                     /locus_tag="LSX49_003939"
                     /pseudo
     CDS             375..605
                     /locus_tag="LSX49_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309956.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            657..1592
                     /gene="ttcA"
                     /locus_tag="LSX49_003940"
     CDS             657..1592
                     /gene="ttcA"
                     /locus_tag="LSX49_003940"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBL7170281.1"
                     /translation="MQENQQITKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLETLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK"
     gene            complement(1720..3093)
                     /gene="dbpA"
                     /locus_tag="LSX49_003941"
     CDS             complement(1720..3093)
                     /gene="dbpA"
                     /locus_tag="LSX49_003941"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HBL7170282.1"
                     /translation="MTAFSTLNVLPPAQLTNLNGLGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQSVCDALNEVGQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVPLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(3571..4554)
                     /gene="zntB"
                     /locus_tag="LSX49_003942"
     CDS             complement(3571..4554)
                     /gene="zntB"
                     /locus_tag="LSX49_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HBL7170283.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
     gene            4809..6041
                     /gene="dgcM"
                     /locus_tag="LSX49_003943"
     CDS             4809..6041
                     /gene="dgcM"
                     /locus_tag="LSX49_003943"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HBL7170284.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSEARLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRNEEETALSCRLVLRELTETEPVI
                     IFEGIEAPATLGLKASRSTNYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(6062..6625)
                     /gene="smrA"
                     /locus_tag="LSX49_003944"
     CDS             complement(6062..6625)
                     /gene="smrA"
                     /locus_tag="LSX49_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HBL7170285.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLSRPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMM
                     FSFIQQALADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(6820..8334)
                     /locus_tag="LSX49_003945"
     CDS             complement(6820..8334)
                     /locus_tag="LSX49_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="HBL7170286.1"
                     /translation="MMSMRKHIAFASMCMGLFIAQLDIQIVSSSLNEIGGGLSAGKDE
                     MAWLQTSYLIAEIIVIPLSGWLSRVFSTRWLFTLSAGIFTLMSIACGLAWNIQIMIFF
                     RALQGAAGASMIPLVFTTAFIYYQGKELGLAAAVVSALASLSPTLGPTLGGWITDNLD
                     WRWLFYINILPGIYLVLSIPFLVNFDKPDLSLLKVADYPSIILLAMTLGCLEYTLEEG
                     ARWGWLDDNTIFLTSVLALVSFILFAARTLTISNPIMDLHAFKDKNFTLGCFFSFSGG
                     VGIFSTVYLIPVFLGRVRGLNAEEIGFAVCTTGIFQLFSVPFYFWLSKKINLRWLLMA
                     GLGGFVFSMYLFTPITHEWGWQELLFPQAIRGISQQFAMAPIVTLTLGGIPKERLKLA
                     SGVFNLTRNLGGAIGIALCGSILNNRTNFHFSRMGEKMVSVPHTVNDFISRSALFFNR
                     GGSDQTSEILASTKLLSQLMLREAQTMAFSDTFLLISGLLFIAFLLVPAMNKSS"
     gene            complement(8331..9359)
                     /locus_tag="LSX49_003946"
     CDS             complement(8331..9359)
                     /locus_tag="LSX49_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBL7170287.1"
                     /translation="MIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGG
                     NITTVTSKVSGYISAIEVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLES
                     IQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
                     QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVRAPID
                     GIVANRSAHTGSWVEGGTSLVSLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKG
                     EVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLS
                     VTVSVDER"
     gene            9456..10271
                     /locus_tag="LSX49_003947"
     CDS             9456..10271
                     /locus_tag="LSX49_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707689.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7170288.1"
                     /translation="MTITLQPKASPGHHIIGLDSEHLNGGTVPWHKHLYAQLLYPAEG
                     VVRVWAGESVWLVHASSALWLPPQMPHKFVATGNVLLKTVLVSEAESETLGKVCFMTG
                     ISPLLRELLIAINQLPPSQSTTDKQQLRFSALETLILQEIKMGVKMSLELPWPNDERL
                     QQLCENLLNNQGYLPTLDNLADKINVSSRTLMRLFVKETGLTFRHWVQQMHVISAVTL
                     LDDGYSLTKIAHRLGYASAESFGNMFKRRTGYSPGKFTRRLTMHDYAITRQMI"
     gene            10660..10803
                     /locus_tag="LSX49_003948"
                     /pseudo
     CDS             10660..10803
                     /locus_tag="LSX49_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
     gene            10814..11329
                     /gene="ogt"
                     /locus_tag="LSX49_003949"
     CDS             10814..11329
                     /gene="ogt"
                     /locus_tag="LSX49_003949"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBL7170289.1"
                     /translation="MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            11524..12276
                     /gene="fnr"
                     /locus_tag="LSX49_003950"
     CDS             11524..12276
                     /gene="fnr"
                     /locus_tag="LSX49_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HBL7170290.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            12428..13378
                     /gene="uspE"
                     /locus_tag="LSX49_003951"
     CDS             12428..13378
                     /gene="uspE"
                     /locus_tag="LSX49_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HBL7170291.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(13428..13685)
                     /locus_tag="LSX49_003952"
     CDS             complement(13428..13685)
                     /locus_tag="LSX49_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HBL7170292.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            13929..14960
                     /gene="ynaI"
                     /locus_tag="LSX49_003953"
     CDS             13929..14960
                     /gene="ynaI"
                     /locus_tag="LSX49_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HBL7170293.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFE
                     KQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
                     KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKIKTFDNRPLYVPN
                     SLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLV
                     YFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMD
                     NITPADQGR"
     gene            complement(15011..16624)
                     /gene="mppA"
                     /locus_tag="LSX49_003954"
     CDS             complement(15011..16624)
                     /gene="mppA"
                     /locus_tag="LSX49_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide ABC transporter
                     substrate-binding protein MppA"
                     /protein_id="HBL7170294.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESSKEWTKPGNLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
BASE COUNT         4531 a         4114 c         3784 g         4347 t
ORIGIN      
        1 tccctaactc cattcgggtg tcatggctct ttcatttgaa atatattcat atccaatgta
       61 atatttccat gcgcaaatat aatcaccaac catacccatc atttattaca gagaattatt
      121 ttattcaccg aaaggtttca caaaatatcc cctgatagaa aactaaaaaa cactgcataa
      181 tatcgctatt ctggcacttg cgaaaaatta tattctgcac ctgttgtagc gttctatttc
      241 tctgcctggc aacgaatgca caatgtccgc cacagtttct gttctaattt cttcctgtgt
      301 taccgcatcc tgtacgggta gcgcaacacc agcatgctaa gcaaggcttt cccatcagat
      361 ttcactacga ctatttggga gcgagatgga atgcagcagt aaaacgtgct ggtattcgcc
      421 gccgtaatcc gtaccatacg cgacatactt ttgcctgctg gctgttgacg gcaggagcga
      481 acccggcatt tatagccagc cagatggggc atgaaactgc gcagatggtg tatgaaattt
      541 acggtatgtg gattgatgac atgaacgacg aacaggtagc catgttgaat gcgcggttat
      601 cgtagttgca aagtttgccc tcaatatgcc ccatttagta ccagagaact gaaataatgc
      661 aagaaaatca acaaattaca aagaaagaac aatacaacct gaacaaatta caaaaacgtc
      721 tgcgtcgtaa cgtgggcgaa gccattgctg acttcaatat gattgaagaa ggcgatcgca
      781 tcatggtttg cctctccggg ggtaaagaca gctataccat gctggagatt ctgcgcaatt
      841 tgcagcaaag cgcgccaatc aatttttcgc tggtggctgt taacctcgat caaaagcaac
      901 cgggcttccc ggaacacgtt ctgcccgagt atcttgaaac gctgggcgtt gagtacaaga
      961 ttgttgaaga gaacacttac ggtatcgtga aagagaagat tccggagggc aaaaccactt
     1021 gctcactgtg ttctcgtctt cgtcgcggta tcctttatcg caccgcaacg gaactggggg
     1081 cgacgaagat cgcgctgggt caccatcgtg acgatatcct gcaaacgctg ttcttaaata
     1141 tgttctacgg tggcaagatg aaaggtatgc ctccgaaact gatgagcgat gatggcaaac
     1201 atatcgtgat tcgtccgctg gcctactgcc gcgagaaaga tattcagcgc tttgccgatg
     1261 caaaagcgtt cccgattatt ccgtgcaacc tgtgcggttc acagcctaac ctgcaacgtc
     1321 aggtaattgc tgacatgttg cgtgactggg ataaacgtta tccggggcgt atcgagacga
     1381 tgttcagcgc aatgcagaat gtggtgccgt cgcatctgtg cgataccaac ctgttcgatt
     1441 tcaaaggcat tacccacggt tctgaagtgg ttaacggggg ggatctggcg tttgatcgcg
     1501 aagagatccc actacaacca gcgggctggc agccagaaga agatgaaaat cagttggatg
     1561 agttacggct gaatgtggtt gaagtgaaat aaccaggata gcgcccgata cgcaagcgta
     1621 tcgggctact cttatggaag ccgataagac gcggccagcg tcgcatccgg caatgccgaa
     1681 gaagatgttt actcttgcac cctgcaattc aacatttcat tattttaata accgcacccg
     1741 gcacgttttt cctttaatct tcccgccctg taactgtttc catgctttat gagcaacagc
     1801 ctgacgcacc gcgacataaa catgcgccgg atgcacggca attttgccaa tatctgcgcc
     1861 atcaagcccg atgtctcctg tcagcgcacc taatacatca cccgggcgca ttttggcttt
     1921 tttcccgcca tcgatacaca acgttgccat ttctgcttcc agcggcacaa tggaactatt
     1981 cgctggcggc gtttgccagt taagttttat ctgcaacatg tcagaaatga tattggcccg
     2041 ctgtgcttct tccggagcac agaaactgat cgccagaccg ctatttcctg cacgagctgt
     2101 acgaccgatg cgatgtacat gaacttcagg gtcccacgcc agctcaaagt tcaccaccag
     2161 ctcaagcgat tttatatcca gaccacgcgc agcaacatca gtcgcgacca gtacacgggc
     2221 gctaccgtta gcaaaacgta ccagggtctg atcgcgatcg cgttgctcca gatcgccgtg
     2281 taacgacaat gcactttgcc ctacttcatt cagcgcgtcg cagacagact ggcaatcttt
     2341 tttggtattg caaaacacca cgcaagagga tggctgatgc aagcttaata accgttgcaa
     2401 cagaggaatt ttgcctttgc tggatgtctc ataaaattgt tgttcaatag gtggcagagc
     2461 atctgttgag tcaatttcaa tcgctaaagg atcgcgctgc actcttccgc tgattgcggc
     2521 aatggcttcc ggccaggttg ccgaaaacag aagtgtctgc cgagatgctg gcgcaaaacg
     2581 gatgacatca tcaatggcgt cactaaatcc catatccagc atgcggtcgg cctcatccat
     2641 caccagcgta ttcaacgcat ccagtgatac agtgcctttt tgcaggtgat ccagcaaacg
     2701 gcccggcgtt gccacgataa tatgcggcgc atgttgtaac gaatcacgct gcataccgaa
     2761 cggttgacca ccgcacaacg tcaaaatttt ggtatttggc agaaaacgcg ccagccgacg
     2821 caattcacct gccacctgat ccgccagttc acgcgtagga cacagcacta aagcctgggt
     2881 ttgaaatagc gacgcatcaa tttgctgtaa caagccgagg ccaaaagccg ccgttttgcc
     2941 gctgccggtt ttcgcctgca cgcgaacatc ttttccggca aggatcgccg gaagcgcggc
     3001 ggcctgcacc ggcgtcatgg ttaaataacc caacccatta aggtttgtga gttgggcggg
     3061 aggcaaaaca ttcagggtag aaaaagcggt cacaatctat tctcgtggtc atcgacgcaa
     3121 agtcagcagg cgcgtatcct cgcagatcta cgctcacgat gcgacaattt aatcggctct
     3181 tcatcgggtg gtgggtcagg catgggttgc gggcgaggga tcggatcggg cacgggaaca
     3241 ggatcgccag gaatcggttc agggacagga atttgcaaat aaataagtgt cgtcatattt
     3301 ccctccggtc attgggtgga ctcttaaagg gtagacgctg ataaataaca ggcaaaaaaa
     3361 agccgactca tcaaagtcgg cgtcgtacga atcaattgtg ctatgcagta attcaaaaaa
     3421 ggaagtaaga caatatggag cgcaacgccc atcgcttgac gttgcattca cctgcaagag
     3481 agatattgcc ctgaatgggt agagagttta ttgacttcgc tcaaacttta cggcgttttt
     3541 gtatacagac agccgggaaa attgcttttg ttacaaccat ttactacgat gcaaccataa
     3601 agcaacacca ccaataagaa caactaacag aatacaaaaa attgaaaatc cgaattgcca
     3661 tccaccgcca gggatcccac caaggttgac gccaaataac cctgtcagaa acgtactggg
     3721 taaaaagacc attgccatca acgacattgt ataagtacga cgagctaaat tttcctgcat
     3781 cacctgagcg atttcatccg ccatcacgcc agtccgtgct atacaggcgt cgatttcgtc
     3841 aagaccgcgc ccaaggcgat cggcaatatc ctgcatccga cggcgttggt catcgctcat
     3901 ccacggcaaa cgttcactgg caagacgagc ataaacatca cgttgcggtg ccatatagcg
     3961 acgcatcaca attaattgtt tgcgcagcag agccaggaat ccacgcggtg gaatttgctg
     4021 atcgagaaga ttatcttcga ggtcgataat tttatcgtgc agctgctcga taaattcgct
     4081 ggaatgatcg gtcaacgcat cgcacacatc aaccagccac cccccgcaat cggtcggacc
     4141 agtgccctct tccagatcgc tcaccacatc gtccagcgcc agcactttgc gttgtcgggt
     4201 cgaaacaatt aaccgcccgt ccatatatac acgcatggcg accagttgat cggggcgttc
     4261 atcggtgctg ccgtttatac agcgcaatgt aatcagcgtg ccttcaccga gacggctgac
     4321 tcggggccgt gtgctctcgc ccgccagcgc atcacgtacg ttattgggaa gcagcggtgt
     4381 tgtcgccagc cattgggcgc tatcatggtg tacataatta aggtggagcc agcagggatg
     4441 cgcttcatca atcacatctg tattttccag cggtttaacg ccgcctctac catccagcat
     4501 ccatgcaaat actgcatccg ggacattaac gtccgatccc ttaatcgctt ccacagtgcc
     4561 tccatcatca acgcattatt ttgtagtcta gccttctggc cctgttacgc aacatctcat
     4621 caccccatta ccctgaaatg attaataaaa ttctgtctaa attgaataca aaaagcaaaa
     4681 tgcttttccg tatacaaacc gtgtgaagtg ttaaatagcg tctatcatta tcagaattat
     4741 ctgatcatat gacgtggctt ttttgcgatc ggatagcaac aacaattgat aaaaataatg
     4801 ggatctcaat gattacgcac aacttcaata ccctggactt actcaccagt cctgtctgga
     4861 tcgtttcgcc ctttgaggaa cagttaattt atgccaacag cgaggcgcga ctgttgatgc
     4921 aagacctcac gtttagtcag ctacgaaccg gtccctattc cgtctcctca caaaaagaac
     4981 tgccgaaata cctctccgat ctgcaaaatc aacacgatat tatcgaaatc ctcaccgttc
     5041 agcgcaatga agaggaaaca gcattaagct gtcggcttgt tttgcgagag ctgacagaaa
     5101 cagaaccggt gattattttc gaaggtatcg aagcaccggc aacgctgggt ttaaaagcca
     5161 gtcgctcgac aaattatcag cgcaaaaaac aaggttttta tgcgcgcttt tttctgacta
     5221 actctgcgcc aatgttgttg attgacccct cacgagatgg ccaaatcgtt gatgctaacc
     5281 tcgccgctct caatttctat ggttataacc atgaaacgat gtgccagaaa catacctggg
     5341 aaataaatat gctcgggcgt cgcgtcatgc ctatcatgca tgaaatctcg catttacccg
     5401 gtggtcataa acctttgaat tttgttcata aactggcgga tggttcgact cgtcatgtgc
     5461 agacctatgc cgggccgatt gaaatttatg gcgacaagct catgttatgt attgtgcatg
     5521 atattactga gcaaaaacgg ctggaggagc agctggaaca tgctgcccac catgatgcga
     5581 tgacaggatt actgaatcgg cgacagtttt atcacattac cgagccaggc caaatgcagc
     5641 acctcgccat cgctcaggat tacagcttgt tgctcatcga caccgatcgt tttaaacaca
     5701 ttaacgatct ctatgggcat tctaaaggtg atgaggtgtt atgcgccctt gcccgcactc
     5761 tcgaaagttg cgctcgcaaa ggcgatttgg tgtttcgttg gggaggcgaa gagtttgtct
     5821 tattgctacc aagaacccca ctggataccg cgctttcgct ggctgaaact atccgcgtaa
     5881 gcgtggcaaa agtgagtatt tcgggcttac cacgctttac tgtcagcatt ggtgtggcgc
     5941 atcacgaagg aaatgaaagc atcgatgaac tgtttaaacg cgttgatgat gctttgtatc
     6001 gagcgaaaaa tgatggacgc aaccgcgtgc tggcggcata agccacggat gcgtctcgtg
     6061 atcaacgact gcgcttagca tggcgctccc agttttcttg cttcgcctgc gctgttttac
     6121 gtagtgcgac gtaacacgcc ccgctgccgc catgatgcgg tagcgcagtg caatatgcct
     6181 gaacatcatc aaattcggtc agccagcgcg ccacatagct gcggacaata ttggcatgcg
     6241 atttatcatc ccgtcctttg ccatgaataa tcagcacgtt acgcaaacca tccgccaggg
     6301 cttgttgaat gaaactgaac atcattttgc ggcactcttc caccggctgg cgcaaaagat
     6361 tcaggctcgc ctgttgcgga tatttaccac tgcgcagctt atccagcacc ccatgttgca
     6421 acccttcccg ccgaaactcc agcggccgac ttagcgggat gatgtcgaga aatccagtgg
     6481 tgaggaaatt atcaagttgc agcgtgtcga tacgctgcgg cgcacgttgg ttacgcgttg
     6541 gatgccagtg gacatctgta gcacgtttca gcggctggac atcttccatg gcgtcaagaa
     6601 acagcgattt gtcgtcaagg ttcatgtaac ctcctatgca ccttcacacg tcgtgattca
     6661 gacgggttaa ttgttcatac ttactgcatc gttcccttca cagattgaaa caatactcta
     6721 cttcatacct gtgagtatct gcgcaggcgg agcattttat actagcctgt tagcagtatc
     6781 gaacagttta gcccgagttt aattcagcac aggctccgat caggatgatt tattcatagc
     6841 aggaaccaac aaaaatgcga taaataacag accactgatt agcagaaagg tatccgaaaa
     6901 tgccatagtt tgcgcctccc tcagcatcaa ttgactcaat aatttggttg aagccagtat
     6961 ttccgatgtc tggtcacttc ctccgcgatt aaaaaacaaa gcacttctgg aaatgaagtc
     7021 attcaccgta tggggaacag aaaccatttt ttcacccatt ctcgaaaaat gaaaattagt
     7081 tcgattattg agaatagagc cacacagggc aataccaatc gcgcccccaa gattacgtgt
     7141 taaattaaat acaccagagg ctaacttcag ccgttctttt ggaattcccc ccagcgttaa
     7201 tgttacgatg ggggccatcg caaactgctg cgaaatccct ctaattgcct gtggaaacag
     7261 taactcctgc catccccatt cgtgggttat aggggtaaaa agatacattg aaaacacaaa
     7321 tccacccagc cccgccatca acagccatcg cagatttatt tttttactta accagaagta
     7381 aaagggaaca gaaaataact ggaaaatacc tgttgtgcaa acggcaaaac ctatctcttc
     7441 ggcatttaat ccgcgaaccc gccccaaaaa cacaggtatt aaatatacag tagagaatat
     7501 tccaacccct ccagaaaaag aaaaaaaaca tcccagtgtg aaatttttat ccttaaaagc
     7561 atgaagatcc attatcggat tggatattgt aagtgtacgc gcagcaaata aaataaaact
     7621 caccaatgcc agaactgatg tcagaaaaat agtattatca tccagccatc cccagcgcgc
     7681 tccttcttca agggtatatt ccagacatcc cagtgtcatg gccaacagga taatactcgg
     7741 ataatcagca actttcagta aagagagatc aggtttatca aaattaacca gaaaaggaat
     7801 actcaaaact aaatatatgc caggtaatat attgatataa aatagccatc gccagtcgag
     7861 gttatcagtg atccagcccc ccagagttgg ccctagcgtc ggtgacagtg aggccagcgc
     7921 actgactacc gcagcagcca accccaactc tttaccctgg taataaataa acgccgtcgt
     7981 gaaaactaaa gggatcatgg atgcgccagc agctccctgt aaagcacgaa aaaaaatcat
     8041 gatctgaata ttccaagcaa gtccacacgc gatactcatt aaagtaaata ttcccgcgga
     8101 tagagtaaaa agccaacgag tggaaaatac ccgtgacagc cacccagaga gcggaataac
     8161 aataatctca gcaattaaat agctggtctg aagccaggcc atttcgtctt tacctgcgga
     8221 cagaccacca cctatttcat ttagggatga cgatacaatt tgaatatcaa gctgagcaat
     8281 aaataatccc atacacatac tggcgaaagc aatatgttta cgcatagaca tcatctctca
     8341 tcaacactga cggtgacgga cagtcccggg cgaagaagtt gctttaattc ctttgcgtcg
     8401 tcaaatgcaa tccgtaccgg gacacgctga acaattttgg tgaaattgcc agtggcattt
     8461 tctatcggaa tcaagctgaa actggctcct gtcgctgggg aaaggctttc aatgtgaccg
     8521 tgaaacactt cccctttgag aatatcagca cggatctcag ccttcattcc tggcttcatt
     8581 cccgctattt ggttttcttt ataatttgca tcaacccaca actcactgac tggtactagt
     8641 gaaactaacg atgtgccgcc ttccacccaa ctgcctgtat gggcgctgcg gtttgcgaca
     8701 atgccatcaa tcggcgcacg aacaagggta tattccagat ccagtagtgc ctgagtcaaa
     8761 gcggcctgaa cttcttcgat acttgcacgt acgttttctt cctgagcaga taaaactgcc
     8821 agccgttgct tctccaccag gaaatcgttc gcggctttgc gctcctttgc tgcgacctgc
     8881 tggtagtcaa acctggcgtt atcaataatt tgttgcgata ttgccgctga ttgtgcgagt
     8941 ttttcataac gttcagtatc tcgcaggcgc ttttgctcct catgttttac tgcctgccat
     9001 gtttcactgg cactttgaat tatcgactgc tgcatcgcaa tagtggcttg aatgctttcg
     9061 agattggctt tgctactttt tatttttgcc tcaagcctgg cgacatttgc acgataatcc
     9121 cgatcatcga gacgcaggat aatatcgcct ttttttacac tctgattatc gcgcacctct
     9181 atagcagaaa tataaccaga aactttactt gtcaccgtgg tgatattacc accaatgtaa
     9241 gcatcatccg tcgtctgtat aaatcttcct ttgcttaccc accagataaa aaagacaacg
     9301 ccagccaaaa gaataccgat cgctaccacc ccaataagct gttttttaga aattatcatc
     9361 actctttaca ccgtatatat ccggaaactt gcatacgtca tatttaaaat ttaacatggc
     9421 ttatttgatg atttctgaca aaatacctac tgtaaatgac aatcacactg caacccaaag
     9481 catcaccagg gcatcacatt atcggactgg attcggaaca tctgaatgga ggtacagttc
     9541 cctggcataa acatctctat gcccagttgc tttacccggc tgaaggagtc gttcgtgtat
     9601 gggctggaga aagcgtctgg ctagtgcatg ccagcagcgc gctttggctg cccccacaaa
     9661 tgccgcataa gtttgttgcg acaggcaacg tacttttaaa aaccgtactg gtttcagaag
     9721 cggaaagtga aacgctggga aaagtttgct tcatgacggg tatttcaccc ctgttaaggg
     9781 aattactaat tgcaattaac caacttccac cgtcgcaaag taccacagat aaacaacagt
     9841 tacgtttttc agccctcgag acactgatac ttcaggaaat aaaaatgggg gtgaaaatgt
     9901 cacttgaact cccttggcca aatgatgagc ggctacagca gctttgtgag aatttgctaa
     9961 acaaccaagg gtatctgcca acactggata atctagcgga taaaattaac gtcagtagcc
    10021 gtacactcat gcgcttattt gttaaagaga cgggattaac atttcgccac tgggttcagc
    10081 aaatgcacgt tatttctgca gtgacgcttc ttgatgatgg atattcgttg accaaaattg
    10141 cccatcgtct gggctatgcc tcagctgaat cgttcggcaa tatgtttaag cgtcgaacgg
    10201 gctactcgcc cggtaaattt actcgtcgat taacgatgca tgattatgca atcacaagac
    10261 aaatgattta acttatattt tcgtgaaatc tgtcactgaa gaaaattggc aacggatggg
    10321 taaaaccgtt ataacactgt caccggtcac caggacccca ggccggattt aagacgagga
    10381 tgcactgctg tgtgtactgt agagtctggc ggatgtcgac aggctctatt tttttattca
    10441 ttttttagcc ctgtaaataa ccacattctc gccgggattg gggaatgagt gacgagatca
    10501 gtggtgtctg gcggctatca cgccacagat caaataacag ataacctacg gtaaaatttc
    10561 gctgactgga attatcccac cctcgatcca tgtgatggct tgccctcatt tcttcaggca
    10621 gaaaaatcaa aaaatcgctt aatactatca gactgcgaca aaccagacgc gaaactgggt
    10681 acttactatt cgttagtctt accctatcca cttatctttt tggtggtatg gctgctgatg
    10741 ttgctggcgt ggtatcttgt tggcttgccg ataggtccgg gtatttaccc acgtttgtct
    10801 taagagagaa cggatgctga gattacttga agaaaaaatt gccacgccac tgggtccact
    10861 gtgggtgatt tgcgatgagc aatttcgcct gcgggcggtt gaatgggaag agtacagcga
    10921 acgcatggtg cagctgctgg acatccatta tcgcaaagaa ggctatgagc gcatttctgc
    10981 caccaaccca ggtggtttaa gcgacaagct gcgtgaatat tttgccggta atcttagcat
    11041 tattgatacg cttcccactg ccacgggggg gacgccattt cagcgcgaag tctggaaaac
    11101 actgcgcact atcccctgcg ggcaggtaat gcattatggc caactggctg aacaattagg
    11161 ccgccctggc gcggcgcgtg ccgttggtgc ggcaaacgga tcgaatccca tcagcatcgt
    11221 cgtaccttgc catcgggtta ttggccgaaa cggcaccatg accggatatg caggcggagt
    11281 tcagcgaaaa gagtggttat tgcgccacga aggttatctt ttgctgtaaa cattaaacaa
    11341 tttgtgccag cttgttcaca cttttatgta aagtcaccct taacaactta agggttttca
    11401 aatagataga catatattta catctaatat cggaattctc tgctgttaag gtttgcttag
    11461 acttacttgc tccctaaaaa gatgttaaaa ttgacaaata tcaattacgg cttgagcaga
    11521 cctatgatcc cggaaaagcg aattatacgg cgcattcagt ctggcggttg tgctatccat
    11581 tgccaggatt gcagcatcag ccagctttgc atcccgttca cactcaacga acatgagctt
    11641 gatcagcttg ataatatcat tgagcggaag aagcctattc agaaaggcca gacgctgttt
    11701 aaggctggag atgaacttaa atcgctttat gccatccgct ccggtacgat taaaagttat
    11761 accatcactg agcaaggcga cgagcaaatc actggtttcc atttagcagg cgatctggtg
    11821 ggatttgatg ccatcggcag cggtcatcac ccgagtttcg cgcaggcgct ggaaacctcg
    11881 atggtatgtg aaatcccgtt cgaaacgctg gacgatttgt ctggtaaaat gccgaatctg
    11941 cgtcagcaga tgatgcgtct gatgagcggt gaaatcaaag gcgatcagga catgatcctg
    12001 ctgttgtcga agaaaaatgc cgaggaacgt ctggctgcat tcatctacaa cctgtcccgt
    12061 cgttttgccc aacgcggctt ctcccctcgt gaattccgcc tgacgatgac tcgtggtgat
    12121 atcggtaact atctgggcct gacggttgaa accatcagcc gtctgctggg tcgcttccag
    12181 aaaagcggta tgctggcagt caaaggtaaa tacatcacta tcgaaaataa cgatgcgctg
    12241 gcccagcttg ctggtcacac gcgtaacgtt gcctgattct tccgcataac tcactatcct
    12301 tctgtcatat cattaaattt ttctgattta ttgatctgac agaaggttca tcactgtttc
    12361 attcaccaga tatgggttaa tcttttaatt acaaactgcg ttgacagttg ttgtaaggag
    12421 accctgtatg gctatgtatc agaacatgct cgttgttatc gatcctaacc aggacgacca
    12481 accagcattg cggcgagctg tttatttaca tcaacggatt ggtggcaaaa ttaaagcctt
    12541 tttgccgatc tatgacttct catacgaaat gaccaccctg ctctctccgg acgaacgtac
    12601 cgctatgcgt cagggcgtca tcagccagcg tacagcctgg atccacgagc aggcaaaata
    12661 ttatctcaat gctggcgttc ccattgaaat taaagtggtc tggcataacc gtcctttcga
    12721 agccatcatt caggaagtga tcagcggcgg gcacgatttg gtgctaaaaa tggcgcacca
    12781 acatgaccgt ctggaagcgg tgatttttac gccaacggac tggcatctgt tacgcaaatg
    12841 cccaagcccc gtgtggatgg tgaaagacca gccgtggccg gaagggggta aggcgctggt
    12901 ggcggtgaat ctcgccagtg aagagccgta ccataatgcg ctcaatgaaa aactggtcaa
    12961 agagacgatc gaactggcag aacaagtcaa ccataccgaa gttcatctgg ttggcgctta
    13021 tccggtaacg ccaattaata tcgcgattga actgccggaa tttgacccga gcgtttataa
    13081 cgatgccatt cgtgggcaac atttgctggc aatgaaagct ctgcgacaga aattcggcat
    13141 taatgaaaac atgacgcacg tagaaaaagg tctgccagaa gaggtgattc ctgatttggc
    13201 ggagcactta caggcgggga ttgtggttct gggcacggtc ggacgcaccg gtatttcagc
    13261 agcattcctc ggcaacacgg cggaacaggt gattgatcat cttcgctgcg acctgctggt
    13321 cattaaacct gaccagtatc agacacccgt tgaactggat gacgaagaag acgattaacg
    13381 actcttcaat aactgacaag gcccgagtta tcgggcctat tttttactta ctgctcttcg
    13441 ccgccaagga aataaattcc caacgggatt gccagcaaca cagtaaagac caggctataa
    13501 acaaaaatca tcgatgactg aatcacatac attgatgtcg tccactcaga cagcggaata
    13561 ttgtactgtt ctataacgcc gccgatggtc gcgcgagtca caaccgacgc cgcaataatg
    13621 aaaaccgcca acaaaccaaa gagaaatttc ttccctttcg ctgacttcag tttcgccata
    13681 atcatgatgt aatccttgtg cagacaaatt ttttgttacc taaacgtaac aataccatga
    13741 catttcaccg ttgtctgctc tgaaaacctc acctcttagc tggatttaca atcaacgcat
    13801 tgattagtta gctaatgttg ctacttcctt ccctgactat tgatgatctg aatgaattgt
    13861 cgcggtaaaa tagtcccgcc aggggtttcc ggcatgacga caattatctg gaggagcctg
    13921 ataaaacaat gatcgctgaa ctgtttacaa ataatgcgct taatctggtc attattttcg
    13981 gtagctgcgc agcattgatt ctgatgagct tttggtttcg ccgtggaaat cgtaaaagaa
    14041 aaggattttt attccatgcg gtgcaatttt taatctacac cataattatt agtgctgttg
    14101 gtagcatcat taactatgtt atagaaaact ataaactcaa atttatcacc ccaggcgtta
    14161 tcgattttat ctgtacgtcc ctgattgcgg ttattctgac gattaagcta tttctgctga
    14221 ttaatcagtt tgaaaaacag cagattaaaa aaggtcgcga tatcaccagt gcgcggatca
    14281 tgtcgcgcat tatcaaaatc accattattg tggtgcttgt tctgctttat ggcgaacatt
    14341 tcggcatgag cctttctggc ttgttgacct ttggtggtat tggtggtctg gctgtcggta
    14401 tggccggtaa agatattctg agtaacttct tttccgggat tatgctctat ttcgaccgtc
    14461 ctttcagtat tggcgactgg atccgttcac cggacagaaa tatcgaaggt acagtagcgg
    14521 aaattggctg gcgaattacc aaaattaaga cctttgataa tcgtccattg tacgtaccga
    14581 actcgctgtt ttcgtcgatc agcgtagaaa atcctggacg aatgaccaac cggcgcatta
    14641 ccacgaccat tggtttacgt tatgaggatg cggcaaaagt gggcgttatt gtcgaagccg
    14701 tacgtgagat gctgaaaaat cacccggcca tcgaccagcg acaaacctta ctggtttatt
    14761 tcaaccagtt tgctgattcg tcattaaata ttatggttta ttgctttacc aaaaccacgg
    14821 tatgggctga atggcttgct gcacagcaag acgtttattt gaagattatc gatattgtac
    14881 agtcacacgg cgcggacttt gccttcccca gccagacgct gtatatggat aacattacac
    14941 cggcggacca gggtcgctaa atcagacatc actggcgtta tccacaaggg taacgccagt
    15001 tctcatcaca tcaatgcttc acaatataca tagtccgact gtacgccaca tcttcagggt
    15061 tgttaatggg ataacctttc agccacggct tgattaatcg tccattggta tattgataaa
    15121 ttggtgcaat cggtgcttgc tccatgagga ttttttctgc cgcgttgtaa tcggcattac
    15181 gcgctttaac ggtattttcc gtcgatgcct gggccagaac tttgtcatat gccggattgt
    15241 taaagcgtga aatattcccg gaatgcgttg acgttaataa tgtcaggaaa gtggagggtt
    15301 cattataatc ccctacccac gaggcgcgga taacatcaaa attgccggta ttacggctat
    15361 cgatataggt tttccattcc tggttttgca atttaacatc tacgcccagg ttctttttcc
    15421 acatcgatgc tacagcaatc gcaatttttt gatggttttc tgaagtgtta tacaaaagcg
    15481 tcagcttcag cggtttttgc ggaccataac cagcggcgct caacaaagtt tttgcctgcg
    15541 cattcagttc ttcctgactc atttgttcaa acggcgaagg ttccggcgta aatcccgcgg
    15601 taacatctgg tgtaaaatgc cacgctggct tttcgcccgt ccccaacact ttttcggtca
    15661 tcaggcggcg atctatcgtc atacttaatg ccaggcgaac gcgctgatct gccgtcggcc
    15721 ctttttgcgt gttaaacgca taataatagg tcccgagctg cggcggcgta taaacctgcc
    15781 ccggaatatc cttcaacagc ttctgataca tatttttcgg gaaggattcg gtgatatcaa
    15841 tatcccccgc gagataacgc ttagtggctg cggattcctg attaattggc aggaaggtca
    15901 ctttttgcag taccgttttg gcgttatccc aataatgggt attcggcact acgaccagtt
    15961 tttcattgac tacgcgctct ttaagaacat aagcgccatt gccgatcaga tttccgggtt
    16021 tcgtccactc tttactgctt tctacgttgg ctttttgcac cgggaagaag gcaaagttag
    16081 cggttaaatt cacaaaccac ggcaacggtt tatcaagctg gattttcaaa gtatgggcat
    16141 caactgcggt aacgccaagc tggtcaggcg tggctttacc atcaataatc gcctgtgcgt
    16201 tgttgattcc cgccagcgcg gcaaaccatg caaatggcga aagcgttttc gggtccacca
    16261 gacgttgcca gctgtagaca aaatcttgcg ccgttaccgg tgtgccatcc gcccattttg
    16321 cgttatcgcg cagggtaaaa gtccagatac ggttgtcatt acttttccac tgagtcgcaa
    16381 cgccggggac aatctcccct ttctcgttct gattcaccag tccttcaaac agatcgcgaa
    16441 tgacctgaat ctccggcagg cccacggctt tagcgggatc cagcgacgct ggctcatctt
    16501 taatgtggcg caccagctcc tgcttctctg ccagtactgt gccgctcgga acttcagcag
    16561 catacgaaag agaaatgctg ctgaccaaca gcgcacaaca cgtgactgaa acagagtgct
    16621 tcataagttt ccctctaacc gacattaaaa ttgatgcgta attatttgtt tcgccttaaa
    16681 gaaatgcaaa caacttccat caaaaaagtg acaaaggaag catcaaatgt tttaagtatc
    16741 aatatatcaa atcagattta gtgtaaataa tagtct
//
LOCUS       DAFGPF010000109        16624 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFGPF010000109 DAFGPF010000000
VERSION     DAFGPF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16624
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.109"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..375
                     /locus_tag="LSX49_003955"
     CDS             <1..375
                     /locus_tag="LSX49_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HBL7170295.1"
                     /translation="TALQTVPEQNIDVTNNESALIIKLNDYGDLQINILFTSRQMIIE
                     TFICPVSSISNPDEFNTFLLRNQKMMPLSSVGISSVQQEEYYIVFGALSLKSSLEDIL
                     LEITSLVDNALDLAEITEEYSH"
     gene            394..1092
                     /locus_tag="LSX49_003956"
     CDS             394..1092
                     /locus_tag="LSX49_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
                     /protein_id="HBL7170296.1"
                     /translation="MGILKSLFTLGKSFISQAEESIEETQGVRMLEQHIRDAKAELDK
                     AGKSRVDLLARVKLSHDKLKDLRERKASLEARALEALSKNVNPSLINEVAEEIARLEN
                     LITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKATEAMQRAQQAVTTSTV
                     GASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDEKLAEAGIGGSNKSS
                     AQDVLARLQRQQGE"
     gene            1142..1801
                     /locus_tag="LSX49_003957"
     CDS             1142..1801
                     /locus_tag="LSX49_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HBL7170297.1"
                     /translation="MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLSFRLLEDEL
                     LIALPGEEFTVAAVSHIDLGGGSQIFRYYTSGDEFLQINTTGGEDIDDIDDIKLFVYE
                     ESYGISKESHWREAINAKAMGAMTLNWQEKRWQRFFNSEEPGNIEPVYMLEKVENQNH
                     AKWEVHNFSMGYQRQVTGDTYEYLLLNGEESFNDLGEPEWLFSRALGIDIPLTSLHII
                     G"
     gene            1819..2217
                     /locus_tag="LSX49_003958"
     CDS             1819..2217
                     /locus_tag="LSX49_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HBL7170298.1"
                     /translation="MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNN
                     TAAALAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSE
                     KIINHNTAAGMFMGTAALAGGIFNAACMTW"
     gene            2227..2865
                     /locus_tag="LSX49_003959"
     CDS             2227..2865
                     /locus_tag="LSX49_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HBL7170299.1"
                     /translation="MARKRKSRNNKNIGHGAISRIGRPHNPFEPRRNRYAQKYLTLAL
                     MGGAAFFVLKGCGDSGDVDNDGDGTFYATVQDCIDDGNNSDICAHGWNNAKAAFYADV
                     PKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASR
                     PVWRNTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            2868..4031
                     /locus_tag="LSX49_003960"
     CDS             2868..4031
                     /locus_tag="LSX49_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HBL7170300.1"
                     /translation="MLRHNVPVRRDLDRIAADNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWRARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGVIPRDADQYNAIQERLI
                     SRFSELYSREPFYFCCCQDTDEDRSTVLYLQDCAEQAGQESRFIYIEELGLGVGGVLT
                     DLDDNVIQRAFKLYPLEWMMRDDNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFDGEKPQIAAGESYVRKPIYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            4115..5740
                     /locus_tag="LSX49_003961"
     CDS             4115..5740
                     /locus_tag="LSX49_003961"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HBL7170301.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLDDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGIPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     TWCKVMLDTRGGVRLSEQIQNDLLLRATGGVCL"
     gene            complement(5857..6132)
                     /gene="yjfN"
                     /locus_tag="LSX49_003962"
     CDS             complement(5857..6132)
                     /gene="yjfN"
                     /locus_tag="LSX49_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease activator YjfN"
                     /protein_id="HBL7170302.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(6281..6610)
                     /gene="bsmA"
                     /locus_tag="LSX49_003963"
     CDS             complement(6281..6610)
                     /gene="bsmA"
                     /locus_tag="LSX49_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313192.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HBL7170303.1"
                     /translation="MVSRKRNSIIYRFASLLLVLMLSACSALQGTPQPAPPVTDHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIRAKAVAAKADYYVVVMVDETIVTGQWYS
                     QAILYRK"
     gene            6792..7541
                     /gene="yjfP"
                     /locus_tag="LSX49_003964"
     CDS             6792..7541
                     /gene="yjfP"
                     /locus_tag="LSX49_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL7170304.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCVIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQFWQILLQSMQEFTTLRAAIAEEN
                     WLRDDRLAVGGASMGAMTALGITARHPTVKCTASMMGSGYFTSLARSLFPPLIPETAA
                     QQNEFNNIVAPLAEWEATNHLTELGNRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            complement(7538..8293)
                     /gene="ulaR"
                     /locus_tag="LSX49_003965"
     CDS             complement(7538..8293)
                     /gene="ulaR"
                     /locus_tag="LSX49_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HBL7170305.1"
                     /translation="MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLF
                     SRADQIDMLITGKNANPEILQQLEAQGVSILRV"
     gene            complement(8401..9465)
                     /gene="ulaG"
                     /locus_tag="LSX49_003966"
     CDS             complement(8401..9465)
                     /gene="ulaG"
                     /locus_tag="LSX49_003966"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBL7170306.1"
                     /translation="MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGANVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPG
                     GSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMGEALNAKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            9820..11217
                     /gene="ulaA"
                     /locus_tag="LSX49_003967"
     CDS             9820..11217
                     /gene="ulaA"
                     /locus_tag="LSX49_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL7170307.1"
                     /translation="MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIERMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
                     CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVNWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFASRAL
                     RAEEDAEKQLAEQSA"
     gene            11233..11538
                     /gene="ulaB"
                     /locus_tag="LSX49_003968"
     CDS             11233..11538
                     /gene="ulaB"
                     /locus_tag="LSX49_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HBL7170308.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            11548..12012
                     /gene="ulaC"
                     /locus_tag="LSX49_003969"
     CDS             11548..12012
                     /gene="ulaC"
                     /locus_tag="LSX49_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HBL7170309.1"
                     /translation="MKLRDSLAENKSIRLQAEAETWQDAVKIGVDLLVAADVVEPRYY
                     QAILDAVEQHGPYFVLAPGLAMPHGRPEEGVKKTGFALVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            12026..12676
                     /gene="ulaD"
                     /locus_tag="LSX49_003970"
     CDS             12026..12676
                     /gene="ulaD"
                     /locus_tag="LSX49_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL7170310.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIGQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            12686..13540
                     /gene="ulaE"
                     /locus_tag="LSX49_003971"
     CDS             12686..13540
                     /gene="ulaE"
                     /locus_tag="LSX49_003971"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HBL7170311.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETD
                     DRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMT
                     KAGMVEAV"
     gene            13540..14226
                     /gene="ulaF"
                     /locus_tag="LSX49_003972"
     CDS             13540..14226
                     /gene="ulaF"
                     /locus_tag="LSX49_003972"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase UlaF"
                     /protein_id="HBL7170312.1"
                     /translation="MQKLKQQVFEANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKADDMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGDAEPLHTP
                     GIVVYQHGPFVWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(14355..14630)
                     /locus_tag="LSX49_003973"
     CDS             complement(14355..14630)
                     /locus_tag="LSX49_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBL7170313.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            14958..15353
                     /gene="rpsF"
                     /locus_tag="LSX49_003974"
     CDS             14958..15353
                     /gene="rpsF"
                     /locus_tag="LSX49_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBL7170314.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            15360..15674
                     /gene="priB"
                     /locus_tag="LSX49_003975"
     CDS             15360..15674
                     /gene="priB"
                     /locus_tag="LSX49_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HBL7170315.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            15679..15906
                     /gene="rpsR"
                     /locus_tag="LSX49_003976"
     CDS             15679..15906
                     /gene="rpsR"
                     /locus_tag="LSX49_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBL7170316.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            15948..16397
                     /gene="rplI"
                     /locus_tag="LSX49_003977"
     CDS             15948..16397
                     /gene="rplI"
                     /locus_tag="LSX49_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBL7170317.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
BASE COUNT         3971 a         4005 c         4445 g         4203 t
ORIGIN      
        1 acggcgctgc aaactgtacc tgaacaaaat attgatgtaa caaataacga aagtgcatta
       61 attattaaac tgaatgatta tggcgatttg caaatcaata ttctttttac ttcccgccaa
      121 atgatcatcg aaacctttat ttgtccggta agtagtatca gcaatccaga tgaatttaat
      181 accttcttat taagaaatca gaagatgatg ccgttgtcat cggtagggat ctccagcgtg
      241 caacaggaag agtattacat tgttttcggt gcgttatcgc ttaaatcttc tcttgaagat
      301 atcctgcttg agataacctc gctggtagat aacgcattgg atctggctga aattacagaa
      361 gaatattcac actaattaca aggacgggta tttatgggaa ttttaaaaag tttatttacg
      421 ctggggaaat cgtttatctc ccaggcggaa gagtccattg aagaaaccca gggcgtgcgc
      481 atgctggaac agcatattcg tgacgctaaa gctgaactcg ataaagccgg aaaatctcgc
      541 gttgatctgc tggcacgggt gaaattaagt cacgataagc tgaaagattt acgtgagcgc
      601 aaagccagtc tggaagcgcg tgcgctggaa gcgttaagca agaacgttaa tccgtcgttg
      661 attaacgaag ttgctgaaga aatcgcgcgc cttgagaatc tcattaccgc tgaagagcaa
      721 gtgttgtcga atctggaagt ctctcgtgat ggcgtggaaa aagcagttac agcgacagcg
      781 cagcgtatcg ctcagtttga gcagcaaatg gaagtcgtta aagccactga agccatgcag
      841 cgtgcacaac aggctgtaac gacctctacc gttggcgcat cttccagcgt ttcgacagcg
      901 gcagaatcct taaaacgcct gcaaacgcgt caggccgaac gtcaggctcg cctggatgct
      961 gccgcacagt tggaaaaagt cgcggacggt cgcgatctcg atgaaaagct ggcggaagct
     1021 ggaattggcg gtagcaataa aagtagcgcc caggatgtat tagcaagact gcaacgccaa
     1081 cagggcgagt aattttttgc cagcctcact gcaaggctgg taactatttt aaggataaaa
     1141 tatgtctggt tttttccagc gtctgtttgg caaggataat aagcctgcta tcgctcgcgg
     1201 tccgctgggt ctgcatctca atagtggctt tacgctcgac acattatcgt ttcgtttgct
     1261 ggaagatgaa ttgctgattg cgctgccggg tgaggaattt acggtagccg ctgtcagcca
     1321 catcgatctg ggcgggggta gccagatttt ccgttactac acttcgggcg atgagttcct
     1381 gcaaatcaat accactggcg gcgaagatat tgatgacatt gatgatatca agctctttgt
     1441 ctatgaagag agctacggta tcagtaaaga gagtcactgg cgcgaggcga tcaacgccaa
     1501 agcgatgggg gcaatgacct taaactggca ggaaaaacgc tggcagcgat tttttaacag
     1561 cgaagaaccg ggaaatatcg aacccgtcta catgctggaa aaagtagaaa atcaaaacca
     1621 tgccaaatgg gaagtgcata attttagcat gggctaccaa cggcaggtga ccggagatac
     1681 ttacgaatat ttgctgttaa atggtgagga atcttttaac gatctcggcg agccggagtg
     1741 gttattttcg cgcgcgctgg gtatcgatat cccgctgaca tcacttcata ttattggtta
     1801 attacaagga cgtttacaat gcatatactg gattcacttc ttgcttttag tgcctatttt
     1861 tttattggcg tggcgatggt gattattttc ctgtttatct actccaaaat tacaccgcac
     1921 aacgaatggc agttaatcaa aaacaataac accgcggcgg cactggcgtt cagcggaaca
     1981 ttgttggggt acgtgatccc cttatccagt gcggcaatca atgcggtgag tattccagac
     2041 tatttcgcat ggggcgggat tgctctggtg attcaattac tcgtttttgc tggcgtcagg
     2101 ctttatatgc ccgcattaag cgaaaaaatt attaatcaca ataccgcagc cggaatgttt
     2161 atgggaaccg ccgcgctggc tggcggtatt tttaacgcag cttgtatgac atggtaatgg
     2221 acgatcatgg ccagaaaacg caaatccaga aataacaaaa atatcggaca tggggcaatc
     2281 agtcgcattg gtagaccgca taatcctttt gagccgcgcc gcaatcgcta cgcacaaaaa
     2341 tacttaacgt tggcgctaat gggcggtgcc gcttttttcg tattgaaagg ttgtggcgat
     2401 agtggcgatg tcgataacga cggcgacgga acgttttacg cgactgtgca ggattgtatt
     2461 gatgatggta ataattcaga tatctgtgct catggctgga acaacgccaa agcggcattt
     2521 tatgccgatg ttccgaagaa tatgactcag cagaattgtc agtctaagta tgaaaattgt
     2581 tactacgaca atgttgaaca gagttggatc ccggtcgttt ctggattttt gttaagccgg
     2641 gttattcgta aagatcgcga tgagccgttc gtctataaca gcggcggatc ctcatttgct
     2701 tcccgccccg tctggcgcaa cacttccggt gattactcct ggcgctccgg ttctggcaaa
     2761 aaagagtctt actcttcggg cggctttacc accaaaaaag cgtcaaccgt ttctcgcggc
     2821 ggctatggtc gttcttccag cgcccgtggg cattggggag gctaatcatg ctgagacaca
     2881 acgttcctgt gcggcgggat ctggaccgga ttgccgccga taacggattt gactttcata
     2941 tcatcgacaa tgaaatctat tgggatgaga gtcgggctta ccgctttact ctgcgccaga
     3001 ttgaagagca gatcgaaaaa ccgactgcgg aactgcatca gatgtgcctg gaggtggtgg
     3061 atcgtgcggt taaagatgaa gagatcctga cgcaactggc gatcccgccg ttgtactggg
     3121 atgtgatcgc cgaaagctgg cgcgcacgcg atccttcgtt gtatggccgt atggattttg
     3181 cctggtgtgg taatgcaccg gttaagttgc tggagtacaa cgccgatacg ccaacttcat
     3241 tgtacgagtc ggcttatttc cagtggttgt ggctggaaga tgcccggcgc agcggcgtta
     3301 ttccgcgcga tgccgatcag tacaatgcca ttcaggagcg cctgatttca cgctttagcg
     3361 agctttatag ccgggagccg ttttattttt gctgctgtca ggataccgat gaagacagga
     3421 gtaccgtgct gtacttgcag gactgcgccg agcaggcagg gcaggagtct cggtttatct
     3481 acattgaaga gctcggtttg ggcgtcggcg gcgtactgac cgatcttgat gataatgtca
     3541 tccagcgtgc atttaagctg tatccgctgg agtggatgat gcgtgacgat aacggtccgc
     3601 tgctgcgcaa gcgtcgtgag caatgggtgg agccgttatg gaaaagtatc ttgagtaata
     3661 aagggctaat gccgctgctt tggcgcttct tccctggtca tcctaacctt cttgcatcct
     3721 ggttcgatgg tgaaaaaccg cagattgccg ctggcgaaag ctatgtgcgt aaaccgattt
     3781 actcgcgcga aggcggaaac gtcaccattt tcgacggtca gaataacgtt gttgaccacg
     3841 ctgatggtga ttacgccgat gaaccgatga tctaccaggc gtttcaacct ctgccgcgat
     3901 ttggcgatag ctacacactc atcggtagct ggattgtcga tgatgaagcg tgcggaatgg
     3961 ggatccgtga agataacacg ctgatcacca aagacacctc acgtttcgtt ccgcattaca
     4021 ttgctggata agaatgtttt agcaatctct ttctgtcatg aatccatggc agtgaccata
     4081 ctaatggtga ctgccattga tggagggaga cacagtgcac tggcaaactc acaccgtttt
     4141 taatcaacct ataccattaa ataacagcaa cttatacctg tctgatggcg cgctttgcga
     4201 agcggtaacg cgtgaaggtg ctggctggga tagcgatttt ctcgccagta ttggtcagca
     4261 gttaggaacg gctgaatccc ttgaactggg gcggctggcg aatgtgaatc cgcctgaatt
     4321 attgcgctac gatgcgcaag gacgccgtct ggacgatgtg cgttttcacc ccgcctggca
     4381 cctgctgatg caggcgctat gtaccaatcg ggtgcacaat cttgcctggg aagaagacgc
     4441 tcgctccggc gcatttgtgg cgcgcgcggc gcgttttatg ttacatgcgc aggttgaggc
     4501 tgggtcgtta tgtccgataa cgatgacctt tgccgccacg ccattgttgt tacagatgtt
     4561 acccgcgccg tttcaggact ggaccacgcc gctgttgagc gatcgctacg attctcactt
     4621 attgccaggt gggcaaaaac gtggcttgtt gatcggcatg ggaatgacgg aaaagcaggg
     4681 cggttccgat gtcatgagca acaccacccg cgcagagcgt ctggacgatg gttcttatcg
     4741 gctggtgggg cataaatggt ttttctcggt gccgcaaagc gatgcgcatc tggtgctggc
     4801 acagaccgcg ggcggtttgt cctgcttttt tgtgccgcgc tttttgcctg acgggcaacg
     4861 caacgcgatt cgcctcgagc ggctgaaaga taagctgggt aatcgctcta acgccagctg
     4921 cgaagtggaa tttcaggatg ccattggctg gttgttgggg caggaagggg aaggaattcg
     4981 tctgatcctg aaaatgggtg ggatgacgcg ttttgattgc gccctgggta gccatgccat
     5041 gatgcgccgt gcattttcgc tggcgattta tcatgcacat caacgccatg tttttggtaa
     5101 tccattgatc caacagcccc ttatgcgtca tgtcttaagt cgcatggcac ttcagcttga
     5161 agggcaaacg gcgttgctgt ttcgtcttgc gcgagcgtgg gaccggcgcg ccgatgccaa
     5221 agaagctctg tgggcgcgtt tatttacgcc tgcggcgaaa tttgtgatct gcaaacgtgg
     5281 cattccgttt gtggccgaag cgatggaggt gctgggcggc attggttatt gcgaggagag
     5341 cgagctgccg cggctttacc gggagatgcc ggtaaacagt atttgggaag gttccggcaa
     5401 tattatgtgc ctggatgtgc tgcgcgttct caataagcaa gcgggcgtat acgacttatt
     5461 gtcggaagca tttgtggaag tgaaagggca ggatcgctat tttgatcgcg cggttcgtcg
     5521 tttacagcag cagctgcgta agccagctga agaattgggg cgagagatta ctcatcagct
     5581 attcctgctg ggctgcggtg cgcaaatgtt gaaatatgcc tctccgccaa tggcgcagac
     5641 gtggtgtaag gtgatgttag atacgcgcgg cggcgtacgg ttgtcagagc agatccagaa
     5701 tgatttattg ctgcgggcga cgggaggagt gtgtttgtaa gcgtatacga ctgatgcgac
     5761 gctggtttcg atgaactaaa tgaaatattt taaaattgta ggccggacaa ggcgctcgcg
     5821 ccgcatccgg cattgttcat ttgctgtaga tgacactcac gcatacagta tcgcctgtac
     5881 gcgccagtta tcaggctgct ggtcttcgta catggtaata atgcggtacc atgacgcacc
     5941 ttgttcatcg gcctttaacg ccacgatacg ttccacgtcc tgcggatccc ctgaaatatt
     6001 gctaactgag atctgaccta tttcattcag gcccgtcacg cagtcagcac tggcgaattc
     6061 tgcagactgt gccgtggcgc tcgcaggata agtcactaat tgcagcgagg gtgaggcaag
     6121 taattgtttc atcgtcagct ccatttttcg tttccccaca tgttgcaggg cattccatcg
     6181 cggtaataaa cgcccgagct tccagccggt aatttattgt gcacaggtaa acgcataggg
     6241 acgcaaagca atgtaaagct gactatgtta gttgtctgat ttatttacgg tacaaaatgg
     6301 cttgtgaata ccactgtcct gtcacgatgg tttcgtccac catgacgaca acgtaataat
     6361 cagcttttgc agcgacagct ttcgctctga tttctgctaa tgcgtcatcc ggagaacctc
     6421 gaaccatcgt gcttacgcta cctattcgct gtaacccttg cgtctggtca cggcgaatct
     6481 cttgcggatg gtccgttact ggcggtgctg gctgtggcgt accttgcagt gcgctacagg
     6541 cacttaacat caacaccaat aataaactgg caaaccggta aataatgcta ttacgtttcc
     6601 tgctaaccat agtgtagtgc cttattaatt taactttggg ggaatgttcc cgaattgtta
     6661 cctggtacgc gattttcgaa tgaaaacgtg acgaaagcgt aacccacatc tcaacattat
     6721 gaactaatac cgccagcaga aacttgtgct aaggatttct tcatgtcata ccagacaaaa
     6781 aggagagaca gatgattgaa atagaatcac gcgagctggc agatattccc gttcttcatg
     6841 cttatcctgt cgggcaaaaa gataccccgt taccgtgtgt gattttttat cacggcttta
     6901 cttcgtccag tctggtgtat agctattttg ccgttgcgct ggcgcaggct ggtttgcggg
     6961 tgatcatgcc ggatgcgccc gatcacggta gccgttttag tggcgacgca gcgcggcggt
     7021 taaatcaatt ctggcaaatc ttgctacaaa gtatgcagga attcactacc ttacgtgcgg
     7081 caatagccga agaaaactgg ctgcgtgatg accgtctggc agtcggtggc gcgtcgatgg
     7141 gcgcgatgac ggcactggga attaccgctc gccaccccac ggtaaaatgt accgccagca
     7201 tgatgggatc gggctatttt acatcgctcg cccgttcact gtttccaccg ctgatacctg
     7261 aaacggcagc acagcagaat gaattcaata acattgtcgc gccgctggca gagtgggaag
     7321 cgacaaacca tctgacagag ttggggaaca gaccgctgct cttatggcat ggccttgacg
     7381 atgacgtcgt gcctgccgac gaatcactac gtttgcagca ggccttaagc gagacgggac
     7441 gggataaact gctaacctgt tcatggcagc caggcgtgcg tcaccgcatt acgcctgagg
     7501 cgttagatgc tgccgtgaca tttttccgcc agcatcttta aacacgcaga atgctgaccc
     7561 cttgcgcttc cagttgttgc aggatttccg ggttagcatt tttgccggtg atcagcatat
     7621 cgatttgatc ggcacggcta aaaagcattc ccgcgcgttc gccaatctta ctgctatcaa
     7681 ccagtaccac cagtttccct accacgctca gcatcttctg ctctgccatt gccgtcagca
     7741 tatcggtttt atacaaccct tctgctgtca gtcctttgcc gctggtaaac atccagtgcc
     7801 cggcatagag actgttttcg ctgccttgcg ggcttaaagt gatggactga cttttgttgt
     7861 actgtccgcc cataatgatc acgctgtcat gctcctgatc gatcaggtaa tttgccagcg
     7921 gtagataatt agtgatgatt tgcactggct tgccacacat ttcccgccca agcagaaacg
     7981 cggtggagcc gcagttgatg actacgcttt cgcccggatt aaccagctgc gaggccgctt
     8041 tagcaatacg tactttttca tcgtgattct gcgcttgatg cagattcatc ggcgtccagc
     8101 gcgggcgctg ttgggtaata gcttctgcgc cattgcgcac ttttttcagt ttgccgcttt
     8161 cgtcaagttt attgatatcg cgtcgtgcag tggcaggcga aattcccaga cgctcaacga
     8221 ctttctcaac ggtcacaaag cccaattgtg cgagcatttc caggaggatt tgatgtcttt
     8281 gtgcttcagt catgagctat tccgataaaa tttgattttt ttagatgata tttgaaatag
     8341 ccaggaaata ctatgccgga tagcgcgagc atctccacgc tatccggtac aagcgacaga
     8401 ttacaggaac gacttgaacg gcagatctgg ttcaatagtg aagcaatcat cgaaaccacg
     8461 cggatagtgg tactcgaagt tgtctttatc cagcggccag gtaaatttgc cgccgacctg
     8521 ccagataaac ggcttgaagc catacttcag gcgatctttt ttcatctccc acagcacgcg
     8581 gatctcttgc ggatcggcct ggaagtttga ccagatatcg tggtggaacg ggatcactac
     8641 tttcgcattc agcgcttcgc ccatacgcag gatatcagca ctggtcattt tgtcggtgat
     8701 accacgtggg ttctctccgt acgatcctaa agccacgtcg atctgatgct cgttaccatg
     8761 ttttgcataa tagttggagt agtgggaatc gccgctgtga tacagggaac cgcccggcgt
     8821 tttgaacagg tagtttaccg cgcgatcgtc catgccgtcc ggcagtacgc cagccgcttt
     8881 ttgatcggct ggcagcgtga tcagtgccgt gcggtcgaaa gcatcaagtg catgaatttc
     8941 aatgtctttt accttcacta cgtcgcccgg tttaacgacg atgcaacgct ctttcggtac
     9001 gccccagcca atccacaaat caacgcaggt tttcggtcca atgaacggta cgtcatcagc
     9061 acagttctgc atcacggcag cagcgacgtt aacgtcgata tgatcgttgt gatcgtgagt
     9121 cgccagtacc gcgtcgatct ggcgaatcgc aaacggatca agaacaaacg gggtggtgcg
     9181 caggtttggc tgcagttttt tcacgccagc catgcgctgc atctggtgac cctgtttcat
     9241 taacgggtta ccgtggcttt gtttgccagt accgcaccaa aaatcaacac aaacgttggc
     9301 accgccttct gatttcaacc agattccggt acagccgagc caccacattg cgaaagtgcc
     9361 tggtgcgacc tgctcttgct caatttcttc attcagccag ctaccccact ccgggaaagt
     9421 gctcaggatc caggactcac gggtgatact tttcacttta ctcatcgcca tttaccttcg
     9481 tgatagttca attcgaatca atatgtgatt ggttttgatt aatcctgaca ctattttttc
     9541 aggaaggcaa tgaccatttt ttgacttttt agcaggagag ttattgtgga ttttgagtgt
     9601 agaaagatta aattgaatgt gtaatgcaat taactaaatg aatttaaatg aataaatatt
     9661 tcattccgtg aatcccattc tgtttatgtg gaattatttg cgtgcgacgt cacatttaat
     9721 cataaataat cttgttgtga ttacttttga aaattagagt gagagcacaa cattccgggt
     9781 gtgcgaaata cccggttacc tcttcttcag gagatcgtta tggagatcct ctacaacatc
     9841 tttaccgtgt tttttaacca ggtcatgacc aatgccccgt tgttgctggg tattgtgacc
     9901 tgtctgggtt acatcctact gcgcaaaagt gtcagcgtta ttattaaagg tacgattaaa
     9961 accataattg gtttcatgtt gttgcaggca gggtccggca tcctgaccag caccttcaaa
    10021 ccggtggtgg cgaaaatgtc cgaagtctac ggcattaacg gcgcaatttc cgatacttac
    10081 gcgtcgatga tggcaaccat tgaacgcatg ggcgatgcct atagctgggt gggttacgcg
    10141 gtgttgttag cgctggcgct gaacatctgt tacgtgctgc tgcgtcgcat taccggtatt
    10201 cgaaccatca tgctgactgg tcacatcatg ttccagcagg cggggctgat tgccgttacg
    10261 ctgtttatct tcggctactc catgtggacg accattatct gcaccgcgat tctggtttcg
    10321 ctctactggg gcattacctc caacatgatg tacaagccga cacaggaagt caccgacggc
    10381 tgtggtttct ccattggtca ccagcagcag ttcgcatcat ggattgctta taaagtcgca
    10441 ccgttccttg gcaaaaaaga ggaaagcgtt gaagacctca aactgcctgg ctggctgaat
    10501 attttccacg acaacatcgt ctccacggcg attgtcatga ctatcttctt tggtgccatt
    10561 ctgctctcct ttggtatcga caccgtgcag gcgatggcag gcaaagtgaa ctggacggtg
    10621 tacatcctgc aaaccggttt ctcctttgcg gtggcgatct tcatcatcac tcagggcgtg
    10681 cgcatgtttg tggcggaact ctctgaagca tttaacggta tctcccagcg tctgatccca
    10741 ggtgcggttc tggcgattga ctgtgcggct atttatagct tcgcgccgaa cgccgtggtc
    10801 tggggtttta tgtggggcac catcgggcaa ctgattgcgg ttggtatcct ggtcgcctgt
    10861 ggctcttcaa tcctgattat tcccggcttt atcccgatgt tcttctccaa cgccactatc
    10921 ggcgtgttcg ctaaccactt cggcggctgg cgtgcggcgc tgaaaatttg tctggtgatg
    10981 gggatgatcg aaatctttgg ttgcgtctgg gcagtgaaac tcaccggtat gagtgcctgg
    11041 atgggtatgg cggactggtc gattctggca ccgccgatga tgcagggctt cttctccatc
    11101 ggtatcgcct ttatggccgt catcattgta attgcactgg cttatatgtt cttcgctagc
    11161 cgcgcgctgc gcgcagaaga agatgcagaa aaacaactgg cagaacaatc tgcttaataa
    11221 ggagttttga ttatgaccgt tcgtattctg gctgtgtgtg gtaacggaca aggcagttcc
    11281 atgatcatga aaatgaaagt ggaccagttt ttaacccagt cgaacattga ccacacggta
    11341 aacagctgcg cggttggcga atacaaaagc gagttgagcg gcgcggatat catcatcgct
    11401 tctacccata ttgcgggcga aatcaccgtg accggcaaca aatatgtggt tggcgtgcgc
    11461 aacatgctct ctcctgctga ttttggcccg aaactgctgg aagtgatcaa agagcatttc
    11521 ccgcaggacg tgaagtaagg acgcgccatg aaattacgtg attcgctggc tgaaaataaa
    11581 tctatccgcc tgcaagcgga agcagagaca tggcaggacg cagtgaaaat cggcgttgat
    11641 ctgctggtag cggcagatgt ggtagagccg cgttactacc aggcgattct ggatgcggtt
    11701 gaacagcacg gcccgtactt tgtgctcgcc cccggcctgg caatgccgca cggacgcccg
    11761 gaagagggcg ttaagaaaac cggttttgcg ctggtgacgc tgaaaaagcc gctggagttc
    11821 aaccacgaag ataacgatcc ggtggatatc ctcatcacca tggcggcggt tgatgccaac
    11881 actcaccagg aagtgggcat catgcagatc gtcaacctgt ttgaagatga agagaatttc
    11941 gaccgtttac gtgcctgccg taccgagcag gaagtactgg atctcattga ccgcaccaac
    12001 gcggcagctt aagaaggaat tgaacatgtc attaccgatg ttgcaagtcg cgctggacaa
    12061 ccagactatg gatagcgcct acgaaaccac tcgcctgatt gccgaagaag tcgacattat
    12121 cgaagtgggc accattcttt gcgtaggcga aggcgtgcgt gcggttcgtg acctgaaagc
    12181 gctgtacccg cacaaaatcg tactggctga cgccaaaatt gccgatgcag gcaaaatcct
    12241 ttctcgcatg tgcttcgaag ccaacgctga ctgggtgacc gtaatttgtt gtgcggatat
    12301 caacaccgcc aaaggcgcgc tggacgtggc aaaagagttt aatggcgacg tgcagatcga
    12361 actgaccggc tactggacct gggaacaggc gcagcagtgg cgcgacgcag gcattgggca
    12421 ggtggtttat caccgcagcc gtgacgcgca ggccgcaggc gtggcgtggg gcgaagcgga
    12481 cattaccgcg atcaaacgtc tttccgatat gggcttcaaa gtcaccgtca ccggtggtct
    12541 ggcgctggaa gatctgccgt tgtttaaagg cattccgatt catgtgttta tcgctggtcg
    12601 cagcatccgt gatgcagcct ctccggttga agccgcgcgt cagttcaaac gttccatcgc
    12661 cgaactgtgg ggctaaggag cggatatgtt gtccaaacaa atcccgcttg gcatctacga
    12721 aaaagcgctc cccgctgggg agtgctggct ggaacgactg caactggcaa aaacgttagg
    12781 cttcgatttt gtcgagatgt cagtagatga aacggacgat cgcctttcgc gcctcgactg
    12841 gagccgcgag cagcgtctgg cactggtgaa cgcgattgtt gaaaccggcg tgcgcgtacc
    12901 gtccatgtgc ctttctgctc atcgtcgttt cccgctggga agcgaagatg acgcggtgcg
    12961 ggcgcagggg ctggagatta tgcgtaaagc tatccagttc gcccaggacg tcggcattcg
    13021 cgtgatccaa ctggcgggct atgacgttta ctatcaggaa gccaataacg aaacgcgtcg
    13081 tcgttttcgt gacggcctga aagagagcgt tgagatggca agccgcgcgc aggtcacgct
    13141 ggcgatggag atcatggatt acccattgat gaactccatc agcaaggcgc tgggctacgc
    13201 acactatctc aacaatccgt ggttccagct ctacccggat atcggcaacc tgtcggcgtg
    13261 ggacaacgac gtgcagatgg agttgcaggc cggaatcggg catatcgtcg cggtacatgt
    13321 gaaagacacc aaaccaggcg tcttcaaaaa cgtgcctttt ggcgaaggtg ttgtggattt
    13381 tgaacgttgc ttcgaaacgc tcaaacagag tggctattgc gggccgtacc tgattgagat
    13441 gtggagcgaa acggcggaag atccggcggc agaagtggcg aaagcgcgcg attgggtgaa
    13501 agcgcgcatg accaaagcag gcatggtgga ggcggtataa tgcaaaagct gaaacagcag
    13561 gtgtttgagg ccaacatgga tctgccgcgt tacgggctgg tgacctttac ctggggcaac
    13621 gtcagcgcca ttgaccgcga acgcgggctg gtggtgatca agcccagcgg cgtcgcctac
    13681 gaaaccatga aagcagacga tatggtggtg gtcgatatga gcggtaaggt ggtggaaggg
    13741 gagtatcgtc cgtcttccga cactgcgacg catctcgaac tctaccgtcg ttatccgtcg
    13801 cttggtggta ttgtccatac ccactccact catgccaccg catgggcgca ggcggggctg
    13861 gcgatcccgg cgttaggcac cacgcacgcc gattacttct ttggcgacat cccgtgcacg
    13921 cgcggattaa gcgaagaaga ggtgcagggt gagtacgaac tgaataccgg caaagtgatt
    13981 atcgaaacgc tgggtgacgc cgagccgctg catacgccgg gaattgtggt gtatcagcac
    14041 ggaccgttcg tctgggggaa agatgcccac gatgcggtgc ataacgcggt ggtgatggaa
    14101 gaagtggcga aaatggcgtg gattgcgcgc agtattaacc cacaactgaa tcacatcgac
    14161 agctttctga tgaataaaca cttcatgcgt aagcacggtc ccaacgccta ttacgggcag
    14221 aagtaaaaca cgcgctgcgg aaatttcctt cttcgggaga taactggtct aattccgcag
    14281 ccgtttttca aaaaaagccc cctgcgaagg gggcaaagca aactatggca atgtttcgtt
    14341 ggttatacct ggtgctagcg ataaatatcc gcgctggcgt gcatattgcc gttactcccc
    14401 ggttcccgca tcagaatcac atggtagtac gttgcgcctt gcgcatctgt ctcttcattt
    14461 aatgcctgac gtgcttcact ttcagtggcg aagttatggt tgatataaat cacacctaag
    14521 ctttgcacat catccatatt tctggcctgg tggttattaa tttcaatggc tgcccatgta
    14581 tttgcactta gcaaaagcac agccagaagg gctaaaacac gactgaacat agatacctcc
    14641 tcgacggctg actttgtgtg ctctcctctt gtggtgatct tctgatttaa ttttaatcaa
    14701 tgataaagaa gttgatggtg accatttctg atgcagttgt tcaaaaaaac accatgacga
    14761 agtgtgatga actccaaatc agcgatttag aggttatttg cgaaaggggc gatttatttc
    14821 tgctcagccc ttgagtttag cggggtatgt cagtactata acgcgtcatt tttcagccga
    14881 cctttaacac gttccttgcc tccccgggat tcggctgacc cagacaggag gctgaataat
    14941 ccgtaaggag caattcgatg cgtcattacg aaatcgtttt tatggtccat cctgaccaga
    15001 gcgaacaggt tccgggcatg atcgagcgct acactgctgc catcactggt gcagaaggca
    15061 agatccaccg tctggaagac tggggccgcc gtcagctggc ttacccgatc aacaaactgc
    15121 acaaagcaca ctacgttctg atgaacgttg aagctccgca ggaagtgatc gatgagctgg
    15181 aaactacctt ccgcttcaac gatgccgtta tccgcagcat ggttatgcgt accaagcacg
    15241 ctgttaccga agcatctccg atggttaaag cgaaagacga gcgccgtgag cgtcgcgatg
    15301 atttcgcaaa cgaaaccgct gatgatgctg aagctgggga ttctgaagag taatttctga
    15361 tgaccaaccg tctggtgttg tccggcaccg tgtgcaggac tccccttcga aaggtcagtc
    15421 catcaggaat tcctcactgc cagttcgtgc ttgagcatcg ttctgtgcag gaggaagccg
    15481 gctttcaccg gcaggcgtgg tgccaaatgc ccgttattgt tagcggacac gaaaaccagg
    15541 ccattactca cagtataacg gtcggcagtc gcataaccgt tcaggggttc atttcatgcc
    15601 ataaggcaaa gaacggactg agcaaaatgg ttttgcatgc cgagcagatt gaattgatag
    15661 attctggaga ctagccatat ggcacgttat ttccgtcgtc gcaagttctg ccgtttcacc
    15721 gcggaaggcg ttcaagagat cgactataaa gatatcgcta cgctgaaaaa ctacatcacc
    15781 gaaagcggta agattgtccc aagccgtatc accggtaccc gtgcaaaata ccagcgtcag
    15841 ctggctcgcg ctatcaaacg cgctcgctac ctgtccctgc tgccgtacac tgatcgccat
    15901 cagtaatcgg tcacggtcca ttaatacgac tttgagagga taaggtaatg caagttattc
    15961 tgcttgataa agtagcaaac ctgggtagcc tgggtgatca ggtaaacgtt aaagcgggct
    16021 atgctcgtaa cttcctggta ccgcagggta aagctgttcc agctaccaag aaaaacattg
    16081 aattcttcga agcacgtcgc gctgaactgg aagctaaact ggctgaagtt ctggcagcag
    16141 ctaatgctcg cgctgagaaa atcaatgcac tggaaactgt taccatcgcg tctaaagctg
    16201 gcgacgaagg taaactgttc ggttccatcg gtactcgcga catcgctgac gctgtaactg
    16261 cagctggcgt tgaagtggct aagagcgaag ttcgtctgcc gaacggcgtt ctgcgtacca
    16321 ctggtgaaca cgaagtgagc ttccaggttc acagcgaagt attcgcgaaa gtgatcgtaa
    16381 acgtagtagc tgaataattc gttattcaac gagacgtaaa aacgccgacc agtggtcggc
    16441 gttttgcttt taagtgataa aaaccgcaga aacagacgtt ccctccataa atctcttgct
    16501 attcctttta taaaaagttc gcagtaccca tacctggccc ccagcctcgc cgctggtagt
    16561 tcgtgtcatg ttttttacgc gtaaaacacg acaaaagcat caatacagcg atcgtctcac
    16621 ttgt
//
LOCUS       DAFGPF010000110        16442 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFGPF010000110 DAFGPF010000000
VERSION     DAFGPF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16442
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.110"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(74..994)
                     /gene="speB"
                     /locus_tag="LSX49_003978"
     CDS             complement(74..994)
                     /gene="speB"
                     /locus_tag="LSX49_003978"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBL7170318.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDIIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(1130..1861)
                     /locus_tag="LSX49_003979"
     CDS             complement(1130..1861)
                     /locus_tag="LSX49_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170319.1"
                     /translation="MKKWKLRSALIALAVLLAGCSSNAQYNSSASGNVGTAWGGDVHS
                     TVQGVSAERAWRDPAEMIVISYSTNVPSGYDRVYSIRINELEYAIRDGNFNSLPITRV
                     YDSSNNEPRYIVHARIGMNYQLYIRNYSRNTNYEIVATVDGLDVLNGKQGSLNNNGYI
                     VNAGDSLAIKGFRKDKHTEAAFQFANVADSYAANSAQGDVHNTGVIGFAAFELQGPAQ
                     NALPPCSGQAFPADNNGYAPPPCRK"
     gene            complement(2007..3983)
                     /gene="speA"
                     /locus_tag="LSX49_003980"
     CDS             complement(2007..3983)
                     /gene="speA"
                     /locus_tag="LSX49_003980"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HBL7170320.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE"
     gene            complement(3992..4123)
                     /gene="yqgB"
                     /locus_tag="LSX49_003981"
     CDS             complement(3992..4123)
                     /gene="yqgB"
                     /locus_tag="LSX49_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HBL7170321.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            4259..4474
                     /locus_tag="LSX49_003982"
     CDS             4259..4474
                     /locus_tag="LSX49_003982"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170322.1"
                     /translation="MGITSAGMQSRDAECGERIFTRTVRQVKQQTTVHYFVSPPRPPV
                     KTNPQAKTLFSTRLEVATRKKRRVLFI"
     gene            4778..5932
                     /gene="metK"
                     /locus_tag="LSX49_003983"
     CDS             4778..5932
                     /gene="metK"
                     /locus_tag="LSX49_003983"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBL7170323.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
     gene            6368..7762
                     /gene="galP"
                     /locus_tag="LSX49_003984"
     CDS             6368..7762
                     /gene="galP"
                     /locus_tag="LSX49_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HBL7170324.1"
                     /translation="MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            7839..8336
                     /locus_tag="LSX49_003985"
     CDS             7839..8336
                     /locus_tag="LSX49_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HBL7170325.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLIAK"
     gene            8431..9138
                     /gene="endA"
                     /locus_tag="LSX49_003986"
     CDS             8431..9138
                     /gene="endA"
                     /locus_tag="LSX49_003986"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HBL7170326.1"
                     /translation="MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     AAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            9218..9949
                     /gene="rsmE"
                     /locus_tag="LSX49_003987"
     CDS             9218..9949
                     /gene="rsmE"
                     /locus_tag="LSX49_003987"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003853382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBL7170327.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            9962..10912
                     /gene="gshB"
                     /locus_tag="LSX49_003988"
     CDS             9962..10912
                     /gene="gshB"
                     /locus_tag="LSX49_003988"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HBL7170328.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLY
                     LINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQVGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            11021..11584
                     /locus_tag="LSX49_003989"
     CDS             11021..11584
                     /locus_tag="LSX49_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HBL7170329.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLE
                     NLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDN
                     TVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
                     PIADRWREAAKLIGVDILTMPGVAGHA"
     gene            11584..12000
                     /gene="ruvX"
                     /locus_tag="LSX49_003990"
     CDS             11584..12000
                     /gene="ruvX"
                     /locus_tag="LSX49_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBL7170330.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNL
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(12115..13095)
                     /locus_tag="LSX49_003991"
     CDS             complement(12115..13095)
                     /locus_tag="LSX49_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBL7170331.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDAPDV
                     EELLREWLDDDQRTILLENGQLDFAVSLAENQRLRGSAFAQRQGISLALRLLPSHCPQ
                     LEQLGAPPVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMLTFQQSYQQRVGEGRL"
     gene            13113..13817
                     /gene="yggS"
                     /locus_tag="LSX49_003992"
     CDS             13113..13817
                     /gene="yggS"
                     /locus_tag="LSX49_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HBL7170332.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            13835..14401
                     /gene="yggT"
                     /locus_tag="LSX49_003993"
     CDS             13835..14401
                     /gene="yggT"
                     /locus_tag="LSX49_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HBL7170333.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            14398..14688
                     /locus_tag="LSX49_003994"
     CDS             14398..14688
                     /locus_tag="LSX49_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HBL7170334.1"
                     /translation="MSAVTVNDGGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            14696..15289
                     /locus_tag="LSX49_003995"
     CDS             14696..15289
                     /locus_tag="LSX49_003995"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HBL7170335.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTGLPAIADDSGLAVDVLGGAPGIYSARYSGEDATDQKNLQKL
                     LETMKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            15282..16418
                     /gene="hemW"
                     /locus_tag="LSX49_003996"
     CDS             15282..16418
                     /gene="hemW"
                     /locus_tag="LSX49_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HBL7170336.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     NDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEAAPRVEFIQYTGLS
                     EEVIRSQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
BASE COUNT         3984 a         4368 c         4211 g         3879 t
ORIGIN      
        1 tgtaggtcgg ataaggcgtt cacgccgcat ccgacattaa tgacacatca cccgtgcgcc
       61 tcttatctgg cgcttactcg ccctttttcg ccgcctgaat atacagcatc tccagcgcca
      121 gcgtcgccgc agccagagcg gtgatttccg actgatcgta tgccggagcc acttccacta
      181 cgtccatccc aacgatgttg agatctttca ggccgcgtac cagtttaatg gcgcgatcgg
      241 aggtcaggcc gccaattacc ggcgtaccgg tgcctggtgc aaaagcagga tccaggcagt
      301 cgatatcaaa ggtcaggtaa accggcatat cacccacaat ctgtttcacc tgggcgataa
      361 tgtcatccac gctgcgatcg ttcacctggc aggcgtccag cacggtaaag ccgttgtctt
      421 tatcaaactc ggtacgaata ccaatctgca cggaatgatt cgggtcgatc agaccttctt
      481 tcggcgcggt atagaacatg gtgccgtggt caaattcaca accgttcgca taggtatcgg
      541 tgtgggcgtc aaagtgtacc aacgccattt tgccgaaatg cttcgcatga gcgcgcagca
      601 gcggcagcgt aacaaagtgg tcaccaccga aggagagcat acgcttaccg gcagccagca
      661 gcttctcggc gtgcgcctgc agcttctcgc tcatctcacg ggcatcgccg aaggcatata
      721 ccagatcacc gcagtccacg acgttcaggc gctcacgcat gtcgaaattc cacgggaagc
      781 ggttgtgttc ccaggccaga ttcgtcgaaa cctgacggat cgctgccgga ccgtgacgac
      841 cacccgcacg accagaagtg gccatatcga acggcacgcc agtaatcacc cagtcagcat
      901 cgctgtcata cggctggaag ttcatcggca ggcgtaaaaa accaaaggcg ttggaaacca
      961 gtgagttatc gtattgatga cctaaggtgc tcatggatgg actcctttta caaagtcgat
     1021 ataaaaaaac ccttccgcgt cgttaggccc gacgaggaag ggttggattt gcgaaacaca
     1081 agtttgtgct aattatcgcc ttaaatgggc gaggcatcaa gcgaggttgc tatttccgac
     1141 acggtggtgg cgcatagcca ttgttatctg ccggaaacgc ttgtccagag cacggcggca
     1201 gcgcgttttg cgccgggcct tgtaattcaa aggcggcaaa gccgattaca ccggtattat
     1261 gcacatcgcc ttgcgccgaa ttggctgcgt aggaatcagc aacgttggcg aactgaaaag
     1321 ccgcttcggt atgtttatct ttgcggaatc ctttaatcgc taacgaatct ccggcattca
     1381 caatataacc gttgttattc agcgaacctt gcttgccgtt cagcacatcc aggccatcaa
     1441 ccgtagcaac gatctcgtag ttggtgttac gactgtaatt acggatatat aattgataat
     1501 tcattccgat tctggcatgg acaatatagc gtggttcatt attggatgaa tcataaaccc
     1561 gcgtaatagg tagagaatta aaattaccat cgcgaatagc atattccagt tcgttaatac
     1621 gaatactata aacgcggtcg tagccggaag gaacattagt cgaataacta ataacgatca
     1681 tctctgccgg atcgcgccag gctcgttcag cagatacgcc ctgaaccgtt gagtgcacat
     1741 ccccacccca ggcggtgccg acattacccg atgcactgct attatactgc gcattactgg
     1801 aacaaccggc cagcagcacg gctaatgcta tcaacgcgct acgtaatttc cattttttca
     1861 taaccgttcc ctctgcattt aattaatgca gcgattgtag ggagattatt taataagaaa
     1921 agcagctaaa ttatttttaa gaatatataa aaagaaagcg ggccgattta cgtaaataaa
     1981 tcgccccgcc agcggaataa tcttaattat tcatcttcaa gataggtata accgtacaaa
     2041 cctgcctcga actcttcaag gaactgttgt tgcagttcag catcaagatc ggttttcttc
     2101 acctgatcgc ggaactgagt taacagcgtt ttcggatcga gctgcacata ttgcagcatg
     2161 tccgccacgg tatcgccttc gtcagacagt tctacctcta cgctaccatc agggaagacg
     2221 aacacgtcaa ccgcttcggt atcaccgaac aggttgtgca tgttgccaag gatctcctga
     2281 tatgcgccga ccataaagaa accgagcatc ggcggattct ccggatcgta ctccggcata
     2341 ggcattgtcg tggcaatacc gtcaccatca atatagtggt cgatagcacc gtctgagtca
     2401 caggtaatat ccaacagcac agcgcggcgt tccggcactt gatccagccc ttccagcggc
     2461 agaaccggga acaactggtc gatcccccac gcatccggca tcgactggaa cagcgagaag
     2521 ttgacgtaca ttttgtccgc catacgttcc tgcagctcgt cgataatcgg acgatgagca
     2581 cggttttgcg gatccagctg cttttgcact tcatggcaca tgctcaaata aagctgctca
     2641 gcccatgcgc gttcttgcag gctaaaggtg ccggaagagt agccgatatg aatatcgtgc
     2701 agatccatct ggctgtcgtg taaccattca cgcagagaac ggcgagttcc cggttcgtgc
     2761 atttcctgcc aggtttccca catgctttgc agggcgcgcg gtgcgtcttc tgcaggcgcg
     2821 gtcggcaccg tgtattcgtt acgttccacg ccgatgatat tcgacaccag cacggtgtga
     2881 tgcgcagtca ccgcacgacc cgattcggtg attaccgtcg gatgtggcag accattttct
     2941 tcacacgcat caccaatcgc ccagatgatg ttgttggcgt attcattgag gccgtagttc
     3001 accgaacagt cggactgcga acgggtgcct tcatagtcca cgcccagacc gccgccgacg
     3061 tcgaagcact gaatattgac gcccagcttg tgcagctcaa catagaaacg cgcggattca
     3121 cgaacgcctg tcgcgatatc gcgaatattc gccatctgcg aaccgaggtg gaagtgcagc
     3181 agttgcaggc tgtcgagacg cccggcttca cgcagggttt caaccagttg cagtacctga
     3241 gtcgccgcca ggccgaactt cgatttttcc ccgccggagg actgccattt accggagccc
     3301 tgcgaagcca gacgtgcacg cacgcccaga cgaggaacga cattcagacg ttctgcttca
     3361 tccagcacaa tggcaatttc tgacatcttc tcaatgacca gatagacctt gtggcccatc
     3421 ttctcgccaa ttaatgccag acggatatat tcgcggtcct tataaccgtt gcagacgatg
     3481 acgctacggg tcatgccagc atgtgccagc accgccatca actcagcttt ggaaccggct
     3541 tccaggccca gcggttcgcc cgaatgaatc agggactcaa tcacgcggcg gtgctggtta
     3601 actttgatcg gataaacgag gaagtaatcg ccgttatagc cgtaggattc ccgcgcacgt
     3661 ttgaacgcgg cgttaataga acgcaaacgg tgctgcagga tctgcgggaa acagaacagt
     3721 gcaggcagac gctggccctg tgcttcacga gttttcacta actgcgcgag atcgacgcga
     3781 gcttccggga cgtccgggtc cgggcacacg ctgatgtggc ccagctcgtt aacgtcatag
     3841 tagttattgc cccaccaggc aatattgtaa gtacgcagca tcttgctggc ttcctgggag
     3901 ctcattgcaa cctcctgcat ggagcgtagt acaccgtgtt cgcccgctga cgaaggcaaa
     3961 cccatagaca tgtcgtcaga catagcgaac ctcaaattat tttattaagt gtaaaacagt
     4021 taacgactat cgcagcctgg aactgcgata acaacccata agcacatgga ttttccagca
     4081 gtgaatgctg acgctccaac tgcgcaaccg gtttcttttt cataacatta ttaagcacat
     4141 aaccgaacgt aagtgtgaca gttcggcgaa accacgagaa aactcttgtt tttacaagag
     4201 cgcccttgtt cagtcctcag tagctgtaac cagctcttga atcctgagaa gcgccgagat
     4261 gggtataaca tcggcaggta tgcaaagcag agatgcagag tgcggggaac gaatcttcac
     4321 cagaacggtg agacaggtta agcagcagac aacggttcat tatttcgtat cacctccacg
     4381 gccgcctgtt aagacgaacc cacaagccaa aactctgttt tcaacccggc tggaagtggc
     4441 aacacgaaag aaacgtcgtg tgctttttat ttaagccgcg cgccgcgttt tataccccac
     4501 aatggcagaa aattgcaaaa gataaatacg cagaatgcca gcattgtcag gaaaaatttc
     4561 cagccacgtt tttaacagaa tgagacacga ttcaaaaaaa agtggaaatt gggtgaagaa
     4621 ctgacctaaa atagccatcc agatgttaat ccatccatac cgattaacac tcagactgcc
     4681 agtgttttta acctgcagag tcgtggtagg atccgctacc acagaaaatc cacacaacag
     4741 tttgagctaa ccaaattctc tttaggtgat attaaatatg gcaaaacacc tttttacgtc
     4801 cgagtccgtc tctgaagggc atcctgacaa aattgctgac caaatctctg atgccgtttt
     4861 agacgcgatc ctcgaacagg atccgaaagc acgcgttgct tgcgaaacct acgtaaaaac
     4921 cggcatggtt ttagttggcg gcgaaatcac caccagcgcc tgggtagaca tcgaagagat
     4981 cacccgtaac accgttcgcg aaattggcta tgtacattcc gacatgggct ttgacgctaa
     5041 ctcctgtgcg gttctgagcg ccatcggcaa acagtctcct gacatcaacc agggcgttga
     5101 ccgtgccgat ccgctggaac agggcgcggg tgaccagggt ctgatgtttg gctacgcaac
     5161 caatgaaacc gacgtgctga tgccagcgcc tatcacctat gcacaccgtc tggtacagcg
     5221 tcaggctgaa gtgcgtaaaa acggcactct gccgtggctg cgcccggacg cgaaaagcca
     5281 ggtgactttc cagtatgacg acggcaaaat cgttggtatc gatgctgtcg tgctttccac
     5341 tcagcactct gaagaaatcg accagaaatc gctgcaagaa gcggtaatgg aagagatcat
     5401 caagccgatt ctgcccgctg aatggctgac ttctgccacc aaattcttca tcaacccgac
     5461 cggtcgtttt gttatcggtg gcccgatggg tgactgcggt ctgactggtc gtaaaatcat
     5521 cgttgatacc tacggcggca tggcacgtca cggtggtggt gcattctctg gtaaagatcc
     5581 atcaaaagtg gaccgttccg cagcgtacgc agcacgttat gtcgcgaaaa acatcgttgc
     5641 tgctggcctg gccgatcgtt gtgaaattca ggtttcctac gcaatcggcg tggctgaacc
     5701 gacctctatc atggtggaaa ctttcggtac cgagaaagtg ccttctgaac aactgactct
     5761 gctggtacgt gagttctttg acctgcgtcc atacggtctg attcagatgc tggatctgct
     5821 gcacccaatc tacaaagaaa ccgcagcata cggtcacttt ggtcgcgaac atttcccgtg
     5881 ggaaaaaacc gacaaagcgc agctgctgcg cgatgctgcc ggtctgaagt aatttttctt
     5941 cacctgcttt taaaggccag cctcgcgctg gcctttttct tttacctcac cgcggtggat
     6001 aggcgttcat gccgcatccg gcaaaaagct gcccgcacaa taacatcatt cttcctgaac
     6061 acgttttacc gcaaattatc atcgctactg aaaccgatta caccaaccac gccagccaaa
     6121 tatttgtaat attttcatat tattattcag ctttcacagt tgttacattt cttttcagta
     6181 aagtcttaat tgcagataac agcgtttaat ctatgatgat ataactcaat tattttcatg
     6241 tacttaaatc ataactaaga taaatgttag tgtaagcgat tacactgatg tgatttgctt
     6301 cacatctttt tacgtcgtac tcacctatct taattcacaa taaaaaataa ccatattgga
     6361 gggcatcatg cctgacgcta aaaaacaggg gcggtcaaac aaggcaatga cgtttttcgt
     6421 ctgcttcctt gctgctctgg cgggattact ctttggcctg gatatcggtg taattgctgg
     6481 cgcactgccg tttattgcag atgaattcca gattacttcg cacacgcaag aatgggtcgt
     6541 aagctccatg atgttcggtg cggcagtcgg tgcggtgggc agcggctggc tctcctttaa
     6601 actcgggcgc aaaaagagcc tgatgatcgg cgcaatcctg tttgttgccg gttcactgtt
     6661 ctctgcggct gcgccaaacg ttgaagtact gattctttcc cgcgttctgc tggggctggc
     6721 ggtgggtgtg gcttcttata ccgcaccact gtacctgtca gaaattgcgc cggaaaaaat
     6781 tcgcggcagt atgatctcga tgtatcagtt gatgatcact attgggatcc tcggtgctta
     6841 tctttctgat accgccttca gctacaccgg tgcatggcgc tggatgctgg gtgtgattat
     6901 catcccggca attttgctgc tgattggtgt cttcttcctg ccagacagcc cacgttggtt
     6961 tgctgccaaa cgccgttttg ttgatgccga acgcgtgctg ctgcgcctgc gtgacaccag
     7021 cgcggaagcg aaacgtgaac tggatgaaat ccgtgaaagt ttgcaggtta aacagagtgg
     7081 ctgggcgctg tttaaagaga acagcaactt ccgccgcgcg gtgttccttg gcgtactgtt
     7141 gcaggtaatg cagcaattca ccgggatgaa cgtcatcatg tattacgcgc cgaaaatctt
     7201 cgaactggcg ggttatacca acaccaccga gcaaatgtgg gggacggtga ttgtcggcct
     7261 gaccaacgta cttgccacct ttatcgcaat cggccttgtt gaccgctggg gacgtaaacc
     7321 aacgctaacg ctgggcttcc tggtgatggc tgctggcatg ggcgtactcg gtacaatgat
     7381 gcatatcggt atccactctc cgtcggcgca gtatttcgcc atcgccatgc tgctgatgtt
     7441 tattgttggc tttgccatga gtgccggtcc gctgatttgg gtactgtgct ccgaaattca
     7501 gccgctgaaa ggccgcgatt ttggcatcac ctgctccacc gccaccaact ggattgccaa
     7561 catgatcgtt ggcgcaacct tcctgaccat gctcaacacg ctgggtaacg ccaacacctt
     7621 ctgggtgtat gcggctctga acgtactgtt tatcctgctg acattgtggc tggtaccgga
     7681 aaccaaacac gtttcgctgg aacatattga acgtaatctg atgaaaggtc gtaaactgcg
     7741 cgaaatcggc gctcacgatt aatctcctca ggcttcctcc cgtcgcggag gaagccacct
     7801 cttgcagtca tcttttcttc gctctatcct ctgccgctat gaaaacatcc cgtctcccta
     7861 tcgccatcca acaggccgtt atgcgtcgcc tgcgggaaaa actcgcccag gccaacctga
     7921 agctagggcg taactacccg gagccaaaac tctcttacac ccagcgcgga acctccgccg
     7981 gaacagcctg gctggaaagc tatgaaatcc gcctcaatcc cgttttgctg ttggaaaaca
     8041 gtgaagcctt tattgaagaa gtggtgccgc acgaactggc acatttgctg gtatggaaac
     8101 atttcggccg cgtagcgcca catggcaaag agtggaagtg gatgatggaa agcgtgctgg
     8161 gcgttcccgc ccgtcgtacg catcagttcg aactgcaatc cgtgcgtcgc aacaccttcc
     8221 cctaccgctg caagtgccag gagcatcagc ttaccgtacg ccgccataat cgcgtagttc
     8281 gtggcgaggc cgtctatcgc tgtgttcact gcggtgaaca gctgattgca aagtaaccac
     8341 ctgaactatc aggaactttc ctgatctggc tgattgcata ccaaaacaac tttcgctacg
     8401 ttgctggctc gttttaacac ggagtaagtg atgtaccgtt atttgtctat tgctgcggtg
     8461 gtactgagcg cagcattttc cggcccggcg ttggccgaag gtatcaatag tttttctcag
     8521 gcgaaagccg cggcggtaaa agtccacgct gacgcgcccg gtacgtttta ttgcggatgt
     8581 aaaattaact ggcagggcaa aaaaggcgtt gttgatctgc aatcgtgcgg ctatcaggtg
     8641 cgcaaaaatg aaaaccgcgc cagccgcgta gagtgggaac acgtcgttcc cgcctggcaa
     8701 ttcggtcacc agcgccagtg ctggcaggac ggtggacgta aaaactgcgc taaagatccg
     8761 gtctatcgca agatggaaag cgatatgcat aacctgcagc cgtcagtcgg cgaggtgaat
     8821 ggcgatcgcg gcaactttat gtacagccag tggaatggcg gcgaaggcca gtacggtcaa
     8881 tgcgccatga aggtcgattt caaagaaaaa gctgccgaac caccagcgcg tgcacgcggt
     8941 gccattgcgc gcacctactt ctatatgcgt gaccaataca acctgacact ctctcgccag
     9001 caaacgcagc tgttcaacgc atggaacaag atgtatccgg ttaccgactg ggagtgcgag
     9061 cgcgatgaac gcatcgcgaa ggtgcagggc aatcataacc cgtatgtgca acgcgcttgc
     9121 caggcgcgaa agagctaacc tacactagcg ggattctttt tgttaacccc taccccacgc
     9181 gaacaaccgc gtggggagac gacgcggatt tttaactatg cgtatccccc gcatttatca
     9241 tcctgaacca ctgaccagcc attctcatat cgcgctttgc gaagatgctg ccaaccatat
     9301 cgggcgcgta ctgcgcatgg ggccggggca ggcgttgcaa ttgtttgacg gcagcaacca
     9361 ggtctttgac gccgaaatta ccagcgccag caaaaaaagc gtggaagtga aggtgttgga
     9421 aggacagatc gacgatcgcg aatctccgct gcatattcac ctcggtcagg tgatgtcgcg
     9481 tggtgaaaaa atggaattta ctatccagaa atcgatcgaa ctcggtgtaa gcctcattac
     9541 gccacttttt tctgagcgct gcggcgttaa actggatagt gaacgtctga acaagaagct
     9601 ccagcagtgg cagaagattg caattgctgc ctgtgagcag tgtggtcgta accgggtgcc
     9661 ggaaatccgt ccagcgatgg atctggaagc ctggtgtgca gagcaggatg aaggactgaa
     9721 actgaatctt cacccgcgcg ccagtaacag catcaatacg ttgccgttac cggttgaacg
     9781 cgtccgcctg ctgattggcc cggaaggcgg tttatcggca gatgaaattg ccatgactgc
     9841 ccgctatcaa tttactgata tcctgttggg acctcgcgtt ttgcgtacag agacaactgc
     9901 gctcaccgcc attaccgcgc tacaagtacg atttggcgat ttgggctaac ggagaagaat
     9961 aatgatcaag ctcggcatcg tgatggaccc catcgcaaac atcaacatca agaaagattc
    10021 cagtttcgct atgttgctgg aagcacagcg tcgtggttac gaacttcact atatggagat
    10081 gggcgatctg tatctgatca atggcgaagc ccgcgcccat acccgcacgc tgaacgtgaa
    10141 gcagaactac gaagagtggt tttcgttcgt cggtgaacag gatctgccgc tggccgatct
    10201 cgacgtgatc ctgatgcgta aagacccgcc gtttgatacc gagtttatct acgcgaccta
    10261 tattctggaa cgtgccgaag agaaagggac gctgatcgtt aacaagccgc agagcctgcg
    10321 cgactgtaac gagaaactgt ttactgcctg gttctctgac ttaacgccag aaacgctggt
    10381 tacgcgcaat aaagcgcagc taaaagcgtt ctgggagaaa cacagcgaca tcattcttaa
    10441 gccactggac ggtatgggcg gcgcgtcgat tttccgcgtg aaagaaggcg atccaaacct
    10501 cggcgtgatt gccgaaaccc tgactgagca tggcactcgc tactgcatgg cgcaaaatta
    10561 cctgccagcc attaaagatg gcgacaaacg cgtgctggtg gtagatggcg agccggtacc
    10621 gtactgcctg gcgcgtattc cgcagggggg cgaaacccgt ggcaatctgg ctgccggtgg
    10681 tcgcggtgaa cctcgtccgc tgacggaaag tgactggaaa atcgcccgtc aggtcgggcc
    10741 gacgctgaaa gaaaaagggc tgatttttgt tggtctggat atcatcggcg accgtctgac
    10801 tgaaattaac gtcaccagcc caacctgtat tcgtgagatt gaagcagagt ttccggtgtc
    10861 gatcaccgga atgttaatgg atgccatcga agcacgttta cagcagcagt aacccacctt
    10921 agcgagaagg atctcgttga gactctgagt gacagcgccc ttctttccac gcatactggg
    10981 cgctgttgct tttttgaacc aggaaacaga acctctgaca atgaatttac agcatcactt
    11041 tcttattgcc atgcctgctc tccaggatcc gattttccgt cgttccgtgg tctacatttg
    11101 cgaacataat accaatggtg caatggggat catcgtcaac aagccgctgg aaaatctcaa
    11161 aattgaaggg attctggaaa agctgaagat cacgccggag ccgcgtgatg aatcaatccg
    11221 tctggataaa ccggttatgc tcggcggccc tctggctgaa gatcgcgggt ttattttgca
    11281 tactccgccc tccaattttg cttccagcat tcgcatttca gacaacacgg tgatgaccac
    11341 ttcccgcgat gtgctggaaa cgctcggcac cgataaacaa ccgtctgacg tattggtggc
    11401 tctgggctat gcctcctggg agaaaggtca actggaacaa gaaattctcg ataacgcgtg
    11461 gctaacggcc ccggcggatc tgaatattct gttcaaaaca ccgattgccg accgctggcg
    11521 cgaggcggca aaactgattg gtgtggatat tctcaccatg cctggtgtgg cagggcacgc
    11581 ctgatgagtg gaaccttact cgccttcgac ttcggtacca aaagcattgg tgtagcggtc
    11641 ggccaacgca ttaccggcac cgctcgccca ttgcctgcaa ttaaagcaca ggacggtacg
    11701 ccggactgga acctcatcga acgtttactg aaagagtggc agccggacga aatcatcgtc
    11761 ggtttgccgc tgaatatgga cggcaccgag caaccattga ctgccagagc gcgtaaattt
    11821 gccaaccgta ttcatggccg tttcggtgtt gaagtaaagc tccatgacga gcgtcttagc
    11881 accgtggagg cacgttccgg tctgtttgaa cagggcggct atcgggcgct caacaaaggc
    11941 aaagttgact ctgcctctgc ggttatcatt ctcgaaagtt atttcgagca gggatattaa
    12001 ggcgatttac gtcatcgctc cttattgccg gatgcggcgt gaatgactac gtttgtaggc
    12061 ctgataagcg tagcgcatca ggcatattta ctaaaataat caatcacttt agcctcacaa
    12121 acgcccttcc cccacccgct gctgataact ctgctgaaac gttaacatcc ccacctgctg
    12181 cccggtttga ataacatgcg gtaactggtg ggttttccct tcgcgaatca aattccccac
    12241 cgcgggagtg ttaatcagta attcaaacag cgccacgcgt ccttcctgtt tatccacttc
    12301 cagcttttgt gacaacactg cccgtaaact ccccgccagt tgattacgta cgggatcttt
    12361 ttcctgcgcc ggaaatgaat ccaccagccg ctcaactgcc tgcgccgcac cacgcgtatg
    12421 taatgttgcc agcaccaaat gcccggtttc tgccgccgtc agtgccagac ggattgtctc
    12481 gctgtcacgc agctctccga gcaatatcac atcgggatct tcccgcaatg cggcacgcaa
    12541 tcccgatgcg aacgtcatac agtgcaaacc aatttcccgc tgctggatca aacatcgctg
    12601 gctggcatag agatattcaa caggatcttc cagcgtcaga atatgcgcat cggcatgttg
    12661 attgagatag ccaaccatcg ccgccagcgt ggtagatttg ccgctccccg tcgcccccgt
    12721 caccagaatc aggccattct cgctcttgag taattccggc aataccggtg gcgcaccaag
    12781 ctgttcgagc tgtggacagt gcgaaggtaa caaccgtaat gccagagaaa taccttgccg
    12841 ttgcgcgaac gcactgccac gcaaccgctg gttttccgcc agcgacacag caaaatccaa
    12901 ctgaccattc tccagcaata ttgtccgctg atcgtcatcc agccactccc gcagtagctc
    12961 ttcgacgtcc ggcgcatcaa acggcgcagc ttccattcgc ccgcgaatac gccatcgtgc
    13021 gggccaggcg ctgcacaggt gtagatccga gacgttatgc tttacactaa gggccacaat
    13081 ttcttccata ttcatactaa gatcctcgga aaatgaacga tattgcgcat aacctggcac
    13141 aggtccggga caaaatctca gcggctgcaa cgcgttgcgg ccgttctcca gaagaaatta
    13201 cgctgcttgc agtcagtaaa acaaaacctg cgagcgccat cgcagaagcc attgatgccg
    13261 ggcagcgtca atttggtgaa aactacgttc aggaaggggt agataaaatt cgccactttc
    13321 aggaactggg cgtaacagga ttagaatggc attttattgg cccgttgcag tctaataaaa
    13381 gccgcctggt ggcagagcat ttcgactggt gtcataccat cgaccgtttg cgcattgcta
    13441 cccgcctcaa cgatcagcgc ccggcagaac ttccccctct taacgtactg attcaaatta
    13501 atattagtga cgaaaacagt aagtccggga ttcaactggc agaactggac gagctggcag
    13561 ctgcggtcgc tgaactaccg cgtttacgtc tgcgcgggct gatggcaatc cctgcacctg
    13621 agtcagaata tgtaaggcag tttgaagttg cacgccaaat ggctgtagca tttgccggac
    13681 tgaaaacgcg ctacccgcat atcgacacgc tctctctggg aatgtcggac gatatggaag
    13741 ccgccattgc ggcaggtagc acgatggttc gtatcggcac tgcaattttt ggtgcgcgtg
    13801 attactctaa aaaataagga attaaaggaa cgccatgaat acgttgactt tcctgctttc
    13861 aacggtcatt gagctgtata ccatggtgct gttattacgc atctggatgc agtgggctca
    13921 ttgtgatttt tacaacccct tctcacagtt tgtagtgaag gtaacgcagc caattatcgg
    13981 gccactgcgc cgcgttattc cggcaatggg gcccattgac agcgcctcac tgctggttgc
    14041 gtacattctc agtttcatca aagccatcgt gctgtttaaa gtggtgacct tcctgccaat
    14101 catctggatt gccggtttac tgattctgct gaaaaccatc ggcctgctga ttttctgggt
    14161 cctgctggtg atggcgatta tgagctgggt aagccagggg cgtagcccga ttgaatacgt
    14221 gctgattcag ctggccgatc cgctgctgcg cccgattcgc cgcctgctac cggcaatggg
    14281 tgggattgat ttctcgccga tgatcctcgt tctgctgctg tatgtcatca atatgggtgt
    14341 cgcagaagtc ttgcaggcga ccggaaatat gctgctgccg gggctgtgga tggcgttatg
    14401 agtgccgtaa cagtgaatga tggcggtctg gttttacggc tctatattca gccgaaagcc
    14461 agccgtgatt ctattgtcgg tttacatggc gacgaggtaa aagtcgccat taccgcgccg
    14521 ccggttgacg gccaggccaa cagccatctg gtgaagtttc tcggtaagca attccgggtt
    14581 gccaaaagcc aggtggtgat tgaaaaaggc gaacttggcc gccacaaaca aattaaaatc
    14641 attaatccgc aacaaatccc gccagaaatc gcggcgttaa ttaattaggt atcctatgca
    14701 aaaagttgtc ctcgcaaccg gcaatgccgg taaagtgcgt gagctggcgt cgctgcttag
    14761 cgacttcggt cttgatatcg tggcccaaac agacctcggt gtagattccg ctgaagaaac
    14821 tggcctgacc tttatcgaaa acgcgattct gaaagcgcgc catgcggcaa aagtgaccgg
    14881 tttaccggca attgccgacg actccggtct ggcggtagat gtacttggcg gtgcaccggg
    14941 gatttactcc gcgcgttatt ccggtgaaga cgcgaccgat caaaagaatc tgcaaaaact
    15001 gctggaaaca atgaaagacg taccggacga ccaacgtcag gcgcgtttcc actgcgtgct
    15061 ggtatatctg cgtcacgcgg aagatcccac tccgctggtg tgccacggta gctggccggg
    15121 cgtgattact cgtgaaccag cgggcactgg tggctttggt tatgatccaa tcttctttgt
    15181 tccttccgaa gggaaaaccg ctgccgaact gacccgcgaa gaaaagagcg ccatttccca
    15241 ccgtggtcag gcattgaaac tgctgctgga cgctttacgt aatggttaaa ttaccgccgc
    15301 tgagtctcta cattcacatc ccgtggtgcg tgcagaaatg cccgtactgc gatttcaact
    15361 ctcacgcgtt gaaaggagaa gtgccgcacg acgattatgt tcagcatctg cttaacgatc
    15421 tggacaacga tgtggcttac gctcagggcc gtgaagtgca gacaatcttt attggcggtg
    15481 gtacgccgag cctgctttcc ggcccggcga tgcaaacgct gctggacggc gtgcgtgcgc
    15541 gtttgccgct ggcagcggat gcagaaatta ctatggaagc gaacccaggc acggtagaag
    15601 cggatcgctt tgtcgattat cagcgtgctg gtgtgaaccg catctctatt ggtgtgcaga
    15661 gttttagcga agaaaagctg aaacgactcg ggcgtattca tggcccgcaa gaagcgaaac
    15721 gagcggcaaa gctggcgagc ggtttagggt tacgtagttt taaccttgat ttgatgcatg
    15781 ggctgccgga tcaatcactg gaagaggcgc taggcgatct gcgccaggct attgaactga
    15841 atccgccaca tctttcctgg tatcaactga ccatcgaacc taatacgctg tttggctcgc
    15901 gccctcctgt actgccggac gatgacgcgc tgtgggatat tttcgaacag gggcatcagt
    15961 tattaaccgc agcgggctat cagcagtatg aaacatccgc ttacgccaaa cccggttatc
    16021 agtgccagca caatctcaac tactggcgat ttggcgacta catcggtatt ggctgcggcg
    16081 cgcacggcaa agtgaccttc ccggatgggc gcattctgcg taccaccaaa acgcgtcatc
    16141 cgcgtggttt tatgcaggga agatatctgg aaagccagcg tgatgtcgaa gctgcagata
    16201 aaccgtttga gttctttatg aatcgcttcc gtctgctgga agccgcgccg cgcgtggagt
    16261 ttatccaata tactggcctt tctgaagaag ttattcgctc tcagttagac gaggccatcg
    16321 ctcaaggtta tctcacagaa tgtgcggatt actggcagat aaccgagcat ggtaaattat
    16381 tcttaaactc acttcttgaa ttattcctcg ctgagtaatc attaatgcgc ctgcgggcgc
    16441 at
//
LOCUS       DAFGPF010000111        15948 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFGPF010000111 DAFGPF010000000
VERSION     DAFGPF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15948
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.111"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            141..725
                     /locus_tag="LSX49_003997"
     CDS             141..725
                     /locus_tag="LSX49_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7170337.1"
                     /translation="MSKKLGFALSGLMLAMVAGSASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEISEGVLDTTVGAKAKPFSITVDCSKANPAPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINTPSDGVNIALHNIEGSTIKQVKINNPGDIYSKALDATSKS
                     ATYDFKASYVRADASLAATAGYVKTNTAYTVTYQ"
     gene            822..1562
                     /locus_tag="LSX49_003998"
     CDS             822..1562
                     /locus_tag="LSX49_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HBL7170338.1"
                     /translation="MFFNTKYTAALCFATCVAFSSSAIADIVISGTRVIYKSDQKSVN
                     IRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTASS
                     VLPKDRESVFWFNVLEVPPKPDAATVANQSLLQLAFRTRIKLFYRPEALKGNPSEAPL
                     ALKWSWSGSEGKAALRVANPTPYYVSFSSGDLEASGKRFPIDVKMIAPFSDEVMKVTG
                     LNGKANSAKVHFYAINDFGGAIEGNASL"
     gene            1597..4197
                     /gene="htrE"
                     /locus_tag="LSX49_003999"
     CDS             1597..4197
                     /gene="htrE"
                     /locus_tag="LSX49_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HBL7170339.1"
                     /translation="MTIKPTKNYHNHLTRIATFCALLYCNGAFCAELVEYDHTFLMGQ
                     NASNIDLSRYSEGNPAIPGVYDVSVYVNDQPVINQSITFVAIEGKKNAQACITLKNLL
                     QFHINSPDINSEKAVLLARDEALGNCLNLTEIIPQASVRYDVNDQRLDIDVPQAWVMK
                     NYQNYVDPSLWENGINAAMLSYNLNGYHSETPGRKNDSIYAAFNGGMNLGAWRLRASG
                     NYNWMTDSGGNYDFKNRYIQRDIASLRSQFIIGESYTTGETFDSVSIRGIRLYSDSRM
                     LPPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIVT
                     IEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVLKDDIQDEPNLFQASYYYGLNN
                     YLTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTHSNVRIPDDKTYQGQSYRVSWN
                     KLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKSMRNYSRMKNQVT
                     VSINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYSIGYSNSASWGSYSISAQRSWN
                     EDGDADDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQMSSDFKGNNQLNVSSSGYSDNA
                     RVSYSVNTGYTMNKASKDLSYVGGYASYESPWGTLAGSVSANSDNSRQVSLSTDGGFV
                     LHSGGLTFSNDSFSDSDTLAVVQAPGAQGARINYGNSTIDRWGYGVTSALSPYHENRI
                     ALDINDLENDVELKSTSAVAVPRQGSVVFADFETVQGQSAIMNITRSDGKNIPFAADI
                     YDDQGNVIGNVGQGGQAFVRGIEQQGNINIKWLEESKPVSCLAHYQQSSEAEKIAQSI
                     ILNGIRCQIQ"
     gene            4214..4786
                     /locus_tag="LSX49_004000"
     CDS             4214..4786
                     /locus_tag="LSX49_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414680.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7170340.1"
                     /translation="MIKTTPHKIAILMGVLLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKITNKTTESQADFKLVASGCSSGISWIDTTLTGNAL
                     SSSSKLIIPLSGDLSSTTSNIGMGFKKRTTDDATFLQPNNSADKIRWSTEEMQPDKGL
                     EMTVALRETAAGQGVPGIFRALATFNFIYQ"
     gene            4801..5403
                     /gene="yadL"
                     /locus_tag="LSX49_004001"
     CDS             4801..5403
                     /gene="yadL"
                     /locus_tag="LSX49_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HBL7170341.1"
                     /translation="MTFKNLRYGLSSSVVLAASLFSVPSYAATDSIGLTVITTVEMGT
                     CTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKRA
                     TCEGTANDGAGFANGSTATDKASAVAVEVWSTETPATGRATQFSCVTPASQEVTISTA
                     ANAVVYYPMSARLVVEKNKTVSNVTAGKFSAPATFTVTYN"
     gene            5430..6026
                     /locus_tag="LSX49_004002"
     CDS             5430..6026
                     /locus_tag="LSX49_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7170342.1"
                     /translation="MHPTQRKLMKRIILFLSLLFPITCPAIAGQDIDLVANVKNSTCK
                     SGISNQGNIDLGVVGVGYFSGNVTPESYQPGGKEFTVTVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEVTTGAKNVGVVLFSIQDPANIFNVLSSAGNSRSIYPVMTS
                     ALNNSSWKFYARMQKIDPALDVISGQVMSHILVDVHYE"
     gene            6078..7331
                     /locus_tag="LSX49_004003"
     CDS             6078..7331
                     /locus_tag="LSX49_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001462196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin"
                     /protein_id="HBL7170343.1"
                     /translation="MKTFFKYFVFLVLSCSCFTAISKDTSFLVGNNAGVGDGNFNGPS
                     TAAQVTFRYASTTNNLVFYKPTQLGPTGVKLRWEQLDTASGGGFLYCNASDRANPDGL
                     MDIENAMADSGKTYGGHKLFKTSVPGLYYTLFIAKLWSAYSTKTTISDSGLYIGDTTP
                     QKFQWIITDPDLQHIGCDNAMRYDRFWAIGGVVHDLTIEFYTDTDFNPTTNQDVSLSS
                     NSTYLYAFKAYSPGSRVVDHSHHLYIDFDLLNVKLTNPTCFTAVLTGKSVSGSTVKMG
                     EYAPGQIKNGATPVPFDISLQNCVRVGDIETKLSSGKLGTENKQLLGNTLTGSGAAKG
                     VAVLIEGLANRKSALMILKPNDSTSVYKDNTGQAQDHDSDAIYPEDQGITYPLHFQAT
                     LKQDGNIAIEPGEFKATSTFQVTYP"
     gene            7444..8238
                     /gene="panB"
                     /locus_tag="LSX49_004004"
     CDS             7444..8238
                     /gene="panB"
                     /locus_tag="LSX49_004004"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBL7170344.1"
                     /translation="MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFAEEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAA
                     DRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            8250..9101
                     /gene="panC"
                     /locus_tag="LSX49_004005"
     CDS             8250..9101
                     /gene="panC"
                     /locus_tag="LSX49_004005"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBL7170345.1"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIIGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIIAIAGQELNEKGFRADDIQIRDADTLLEVSENSKRAVILVAAWLGDARLID
                     NKMVELA"
     gene            complement(9183..9380)
                     /locus_tag="LSX49_004006"
     CDS             complement(9183..9380)
                     /locus_tag="LSX49_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000404125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL7170346.1"
                     /translation="MEIKTRRETRQTLAQWFEEKGFQKGYKEGLQKVRLALRLLSKGM
                     SREDVAEMANLPLAEIDKMIN"
     gene            complement(9449..10369)
                     /locus_tag="LSX49_004007"
     CDS             complement(9449..10369)
                     /locus_tag="LSX49_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBL7170347.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLDIHLPAELRELCDLDTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGSTGYLHVVIEHQSKPDKKMTFRMMRYAIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNNPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEERGRQEVRQEVRQEVIQEVRQEVRQEF
                     ALRFLSKGMSREDVAEMANLPLAEVDKLIS"
     gene            10643..11023
                     /gene="panD"
                     /locus_tag="LSX49_004008"
     CDS             10643..11023
                     /gene="panD"
                     /locus_tag="LSX49_004008"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HBL7170348.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(11027..12256)
                     /locus_tag="LSX49_004009"
     CDS             complement(11027..12256)
                     /locus_tag="LSX49_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL7170349.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYVFNFGLGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLVTWKDTQVYNAPSVGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMAQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRIDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVLYLSYPFGGFNDKAVKAAKEAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(12320..12760)
                     /locus_tag="LSX49_004010"
     CDS             complement(12320..12760)
                     /locus_tag="LSX49_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL7170350.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHETDSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSAFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            complement(12865..13635)
                     /locus_tag="LSX49_004011"
     CDS             complement(12865..13635)
                     /locus_tag="LSX49_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL7170351.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            complement(13632..14558)
                     /locus_tag="LSX49_004012"
     CDS             complement(13632..14558)
                     /locus_tag="LSX49_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001621186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7170352.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRT"
     gene            14667..15329
                     /gene="can"
                     /locus_tag="LSX49_004013"
     CDS             14667..15329
                     /gene="can"
                     /locus_tag="LSX49_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HBL7170353.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            complement(15370..15906)
                     /gene="hpt"
                     /locus_tag="LSX49_004014"
     CDS             complement(15370..15906)
                     /gene="hpt"
                     /locus_tag="LSX49_004014"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBL7170354.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
BASE COUNT         4374 a         3844 c         3596 g         4134 t
ORIGIN      
        1 acttagtgat gaacagatgt taaattcagt aaatcttcac attcatcatt aacaaactaa
       61 tctcttttcc tctatcggga atccctgcct gaaagggccc aattgtagtt aaactcatgg
      121 aatatgattc aaggattttt atgtctaaaa aattaggttt tgcgctctct ggtcttatgc
      181 tggcaatggt tgcaggtagt gcttctgcag atatggacgg tggtcagtta aatatcagtg
      241 gtctggttgt tgataatacc tgtgaaaccc gcgtagacgg cggtaataaa gatggcctga
      301 tcctgctgca aactgcaacc gttggagaaa tctctgaggg tgtgctggac actaccgttg
      361 gtgctaaggc taaaccattc agcattactg ttgactgtag taaagctaat ccggcaccag
      421 gcagcacagc aaaaatgact tttggttcag tcttctttgg taacagtaaa ggaaccctga
      481 ataatgacat gtcaattaat actccatctg acggtgttaa tattgctctg cacaatattg
      541 aaggttctac tattaagcag gttaaaatca acaatcctgg cgatatctat tccaaagcac
      601 tggatgcaac ttccaaatcc gcaacttatg attttaaagc gtcttatgtt cgtgcagatg
      661 caagtctggc agccacagca ggttatgtaa aaactaacac tgcatatacc gttacttatc
      721 agtaatcact tccattcata ttcataaatt gaatacatac agggaataat attgatactc
      781 catactattt cctgtttttt taactctacc aggaatggtt tatgtttttc aacactaaat
      841 atacagcagc attatgcttc gcaacctgtg tagcttttag ctcgtcagct atagcagata
      901 tcgtaatttc cggtacacgc gtaatctata aaagcgacca aaaaagtgtc aacattcgcc
      961 tggaaaataa aggcaataac ccattacttg ttcagagttg gctggatact ggtgatgaca
     1021 atgctgagcc tggcagtatt accgtcccct ttactgcgac tccgcccgta tcacgcattg
     1081 atgcaaaacg cggccaaacc atcaaactga tgtacaccgc cagcagcgtc ctgccaaaag
     1141 acagagaaag tgtgttctgg tttaacgtac tagaagttcc tccaaaacca gatgccgcaa
     1201 cagttgcaaa tcaaagcctg ctgcaattgg catttcgcac acgtataaaa ctgttctatc
     1261 gcccggaagc attgaagggg aatccctcag aagcaccatt agccctgaaa tggtcctggt
     1321 caggttccga gggtaaagca gcattacgag tggccaatcc aaccccttac tacgtctctt
     1381 ttagcagtgg tgatttagaa gccagcggta aacgctttcc gattgatgtg aaaatgattg
     1441 caccattcag tgatgaagtc atgaaagtca ctggccttaa tggcaaagca aattctgcaa
     1501 aagtgcattt ttacgccatt aatgattttg gtggtgccat tgaaggtaat gccagtctgt
     1561 aatcaggcaa ggatataatt ccgcaggaag cataacgtga ctataaaacc aactaaaaat
     1621 tatcacaatc atctgacccg tatcgccacg ttttgcgcgc tgctgtattg caatggtgct
     1681 ttctgtgctg aacttgttga atatgaccat accttcctga tggggcagaa tgcctcaaat
     1741 attgatctca gccggtatag tgaaggtaac cccgctatac cgggtgtgta cgacgttagt
     1801 gtttatgtca acgatcaacc tgttattaac caaagcatta catttgtcgc aattgaagga
     1861 aaaaagaacg cacaagcctg tatcacactt aaaaatttat tgcagttcca tattaattct
     1921 cccgatataa acagcgaaaa agccgttctg cttgcccggg atgaagctct cggcaattgc
     1981 ctcaatttga cggaaattat ccctcaggct tccgttcgtt atgacgttaa cgatcaacgt
     2041 ctggatatag acgttcctca ggcctgggta atgaaaaatt accaaaacta tgttgatcca
     2101 tcgttatggg aaaatggcat taatgcagcc atgttgtcat acaacctcaa cggatatcat
     2161 agtgaaaccc ctggtcgaaa aaatgacagc atttatgctg cttttaacgg tgggatgaat
     2221 ttgggtgcat ggcggctgcg tgcctcaggc aactacaact ggatgaccga ttctggcggt
     2281 aattatgatt ttaagaatcg gtatatacag cgtgatatcg cctcactacg ctctcaattc
     2341 attattggtg agtcttatac gacgggcgaa acctttgatt ccgtcagtat ccgaggcatt
     2401 cgcttataca gtgacagccg catgttgcct ccgacattag ccagctttgc gcctatcatt
     2461 catggcgttg ccaataccaa cgccaaagtc actattacgc aaggtggcta taagatttat
     2521 gaaacgacgg tgccgccagg cgctttcgtc attgatgatc tgagtccatc agggtacggc
     2581 agtgatctta ttgttaccat cgaagaatcc gatggctcaa agcggacatt ctcgcaacct
     2641 ttttcatcgg tcgttcaaat gttacgccct ggcgttggac gttgggatat tagcggcggc
     2701 caggtcttaa aagatgatat tcaggatgag cctaatttat ttcaggccag ctactactac
     2761 ggtctgaata actatctgac gggttatacc ggtattcaga ttaccgataa taactatacc
     2821 gctggtttgt taggtcttgg tctgaatact tcggtcggtg cattttcttt cgatgtgact
     2881 cactccaatg ttcgtatacc ggatgataaa acataccagg ggcaaagtta tcgtgtttcc
     2941 tggaacaagt tattcgaaga aacaagtact tcactgaata tcgcggccta tcgctattcg
     3001 acacagaatt atcttggtct taatgatgca ctaactctga ttgatgaagt gaaacatcca
     3061 gaacaagatc ttgaaccgaa atccatgcgt aattactcgc gcatgaaaaa tcaggttaca
     3121 gtcagtatta accaaccgtt gaaatttgaa aaaaaagatt acggttcttt ttatctttct
     3181 ggtagttggt ccgattactg ggcttccgga caaaatcgta gcaattactc cattggctac
     3241 agtaacagtg catcctgggg cagctacagc atcagtgcac agcgttcatg gaatgaggac
     3301 ggcgacgctg atgatagcgt ttatctcagt ttcaccattc ctattgaaaa attacttggc
     3361 actgaacaac gtacttcagg tttccagagt atcgatactc aaatgagcag tgactttaag
     3421 ggtaataacc aactcaacgt cagtagcagt ggctatagcg ataacgctcg cgtcagttat
     3481 agcgtgaata ctggctatac gatgaataaa gccagcaaag atttgagtta tgttgggggt
     3541 tatgccagct atgaatcacc gtggggaact ctggcaggtt cagtttctgc aaacagcgat
     3601 aacagtcgtc aagtttctct cagcaccgac ggtggttttg tattgcatag tggcggcctg
     3661 accttcagta atgacagttt tagcgactcc gatacactgg cggtagttca ggctccaggt
     3721 gctcaaggag cgcgaataaa ttatggcaac agtactatcg atcgatgggg ttatggtgtc
     3781 accagcgctc tttctcctta tcatgaaaac cgtatcgcgc tggatatcaa cgatcttgag
     3841 aacgatgttg aattaaaaag taccagtgct gtagctgtgc ctcgtcaggg ttctgtcgtt
     3901 tttgctgatt ttgaaaccgt gcaagggcaa tcagccatta tgaacatcac acgtagtgat
     3961 ggcaaaaata ttccatttgc tgcagatatt tatgatgacc aaggcaatgt cattggtaat
     4021 gttggacagg gtggacaggc ttttgttcgt ggtattgaac agcaaggaaa tatcaacatt
     4081 aaatggctcg aagaaagtaa acctgtaagt tgtcttgcgc attatcaaca aagttcagaa
     4141 gcagaaaaaa tagcgcaatc tattattctg aatggaattc ggtgtcagat tcagtaacta
     4201 caagggacgt caaatgataa aaacaacgcc acataaaata gcgatactga tgggagtatt
     4261 attatcaccc tcagtatttg caacggatat taatgttgag tttacagcca ctgtcaaagc
     4321 gacaacctgt aacatcacac ttactggtaa taatgtcacg aatgatggca ataataacta
     4381 cactttgaga atccctaaga tgggcctgga taagatcacg aataaaacga cagaatctca
     4441 ggctgatttt aaactggttg ccagtgggtg cagcagtggc attagctgga ttgataccac
     4501 tctgaccgga aacgcattat caagctcatc caagcttatt ataccgctgt ctggtgattt
     4561 atcttcgacg acaagtaata tcggtatggg tttcaaaaaa cggactactg atgatgccac
     4621 tttccttcaa cctaacaaca gtgcggacaa gatacgctgg agcacagaag aaatgcagcc
     4681 cgataaaggt cttgaaatga ctgtcgcgct acgtgaaacc gcagcagggc aaggcgtgcc
     4741 ggggattttt cgcgccctgg cgacgtttaa tttcatctat caataagaag gataattaag
     4801 atgacattta aaaatttacg ttatggatta tccagcagtg tcgttttggc tgcctcattg
     4861 ttcagcgtac cctcttatgc ggcaactgac agcattgggc tgaccgtgat taccaccgta
     4921 gaaatgggta cttgtaccgc tacattagta aatgactctg atcaggacat ttctgttgtt
     4981 gattttggtg atgtatatat ttctgaaatc aatgccaaga ccaaagtaaa aacattcaaa
     5041 ctcaaattca aagactgtgc gggtatcccc aataaaaaag cgcaaataaa attaaccaag
     5101 cgagccacat gcgaggggac tgctaatgac ggtgcagggt tcgcaaatgg ttccacagcc
     5161 acagataaag caagtgccgt cgccgttgaa gtctggagca ccgaaactcc ggcaacaggg
     5221 agagcaacac aatttagttg tgtgacacca gcatctcaag aggtaactat ttccactgct
     5281 gccaatgcgg ttgtttatta cccgatgagt gctcgcctgg tcgttgaaaa aaataaaacc
     5341 gtaagtaatg tcactgcagg taaattttct gcacctgcca catttacagt aacctataac
     5401 taacagactg acagattcag gaactatata tgcatcccac tcaacgtaag ctgatgaaga
     5461 gaataattct gtttctgtca ttactgtttc ccattacctg tccagcgatc gctggacagg
     5521 atattgacct tgttgctaat gtaaaaaaca gcacttgcaa aagcggaatc agtaaccagg
     5581 gtaatattga tcttggtgtc gttggggtgg gatatttttc aggtaatgtt actcctgaaa
     5641 gctatcaacc aggtggaaaa gagttcactg tcactgtctc agactgtgca ttacagggaa
     5701 ctggcgatgt gctaaatcag ttacatattg attttagagc ccttagcggt gtcatggctg
     5761 caggctccag gcaaatattt gccaatgaag tgacaaccgg ggctaaaaat gtcggtgtcg
     5821 ttctcttttc cattcaggac ccggccaata tattcaatgt tcttagttca gcgggaaatt
     5881 ctcgttcaat ctatccagta atgacttctg ccctgaataa ttcgtcatgg aaattttatg
     5941 ccagaatgca aaaaatcgat cccgcgctgg atgtcatatc tggccaggtg atgagtcata
     6001 tattagttga tgtgcactac gaataatata tcaaaacaaa cgactgctat tatgacagca
     6061 gcgaatagtg ggtaatcatg aagacattct tcaaatactt tgttttttta gtactatcct
     6121 gctcttgctt tacagcgatt agtaaggata caagttttct tgttggtaac aatgccgggg
     6181 taggcgatgg taatttcaac ggcccgagca ctgcggctca ggtcactttt agatatgcat
     6241 caacaaccaa taatttagtt ttttataaac ctactcaact tggcccgaca ggtgttaaat
     6301 tacgctggga acaattagat acagccagcg gtggcggttt tctttactgt aatgcctctg
     6361 acagggcaaa tccagatgga ctaatggata ttgaaaatgc catggctgat tctggtaaaa
     6421 cctatggtgg acataagtta tttaaaacct ctgtcccagg cttgtattac actctattta
     6481 ttgcaaaact ttggtctgca tattcaacaa aaacaactat tagcgactct ggtttatata
     6541 ttggagatac cacaccacaa aaattccagt ggatcatcac agaccctgat ctacaacata
     6601 tcggctgcga taacgcgatg cggtacgata gattctgggc catcggcggt gttgtacacg
     6661 atcttacgat tgaattttat actgataccg attttaaccc tacaacaaac caggacgtat
     6721 cattgtccag taattcgaca tatctttatg cgtttaaggc ctacagtccc ggttctcgtg
     6781 ttgttgatca cagccatcac ctttatatcg actttgatct actcaatgtt aaattaacta
     6841 accccacctg ctttactgct gtacttaccg gaaaatcagt aagtggttcg acggtaaaaa
     6901 tgggagaata tgcaccaggg cagattaaaa atggtgctac tccggttcct tttgatattt
     6961 ctctccagaa ctgtgttcgc gttggcgata tagagacaaa gctatcttca gggaagctgg
     7021 gtacagaaaa taagcaactc ctgggtaaca ctcttactgg aagcggcgca gcaaaaggcg
     7081 ttgcggtatt gattgaagga ttagcaaaca gaaaaagtgc cctaatgata ctgaaaccga
     7141 atgattcaac ttctgtttat aaagataata cgggtcaggc tcaggatcac gattcagatg
     7201 caatttaccc agaagatcaa ggtataacat atccacttca tttccaggcg acgttaaagc
     7261 aagacggaaa tattgctatc gaaccaggag aatttaaagc caccagtact ttccaggtaa
     7321 cctatccctg ataacattgt ggcaccgtct ggtaatggcg gtgccacaat agataaatca
     7381 ttgcccccac caatgtggct gataaaatgc cagacagcac gacattactt atcaggatac
     7441 gttatgaaac caaccactat tgcttcattg caaaaatgca aacaagaaaa aaaacgtttc
     7501 gcgaccatca ctgcttacga ttatagcttc gcaaaactgt ttgccgaaga aggacttaac
     7561 gtcatgctgg tcggcgattc tctgggcatg acggttcagg ggcatgactc cacgctaccg
     7621 gttaccgttg ctgatatcgc ctaccacact gccgccgtgc gtcgcggcgc gccaaactgc
     7681 cttctgttag cagacctgcc atttatggcg tatgccacgc cggaacaagc ctttgaaaac
     7741 gccgcaacgg taatgcgtgc cggagccaac atggtcaaaa ttgaaggcgg tgagtggctg
     7801 gtagaaaccg tacaaatgct gaccgaacgt gccgttccag tttgtggtca tttaggccta
     7861 accccacagt cagtaaatat tttcggtggc tacaaagtcc aggggcgcgg cgatgaagcg
     7921 gccgatcgac tgctcagcga tgcattagcc ttagaagctg ctggggcaca actgctggta
     7981 ctggagtgcg tgccggttga actggcgaaa cgcattaccg aagcactggc gatcccggtt
     8041 atcggtattg gcgcaggcaa cgtcactgac gggcaaatcc tcgtgatgca cgacgcgttc
     8101 ggcattaccg gcggtcatat tcctaaattc gccaaaaatt tcctcgccga aacgggcgac
     8161 atccgcgcgg ctgtgcggca gtatatggct gaagtggagt ccggcgttta tccgggcgaa
     8221 gaacacagtt tccattgagg agtgacgttg tgttaattat cgaaaccctg ccgctgctgc
     8281 gtcagcaaat ccgccgcctg cgtatggaag gtaagcgcgt ggcgctggtg cccaccatgg
     8341 gtaacctgca cgacggccat atgaagctgg tcgacgaagc caaagcccgc gccgatgtgg
     8401 tcgtcgtcag tattttcgtt aacccaatgc agtttgaccg cccggaagat ctggcacgtt
     8461 atccacggac cttgcaagag gactgcgaaa agctgaacaa acgtaaagtg gatttagttt
     8521 tcgcgccttc ggtaaaagag atctacccga acggtacaga aacccacacc tatgttgatg
     8581 ttcctggtct ttccaccatg ctggaaggtg ccagccgtcc gggacatttt cgcggcgttt
     8641 cgactattgt cagcaagctg ttcaacctgg tccagccgga catcgcttgc ttcggcgaaa
     8701 aggactttca gcaactggcg ctgatccgca aaatggttgc cgatatgggc tttgatattg
     8761 agattatcgg cgtaccgatt atgcgcgcca aagacggtct ggcgctgagt tcccgtaacg
     8821 gttatctgac ggcggaacaa cgcaaaattg cgcccggtct gtacaaggtt ttaagttcga
     8881 ttgccgacaa attgcaggct ggcgaacggg atctcgatga aattattgcc attgccgggc
     8941 aagaactgaa tgaaaaaggc ttccgcgccg atgatattca gattcgtgat gccgacacat
     9001 tgctggaagt ctctgaaaac agcaaacgcg cagtgattct ggtagccgcc tggcttggcg
     9061 atgctcgcct gatcgacaac aaaatggtcg aactggcgta atgcttaact ggcgctacgg
     9121 ctgatggcgc cagctattca ttgccacgtt atctgtaagc gattattcat aacgcagaca
     9181 acttagttaa tcattttatc aatctcagca agaggtaaat ttgccatctc tgcaacgtct
     9241 tcccgagaca ttcctttact cagaagacgc agggccagtc ttaccttctg gagtccctct
     9301 ttatatccct tctgaaatcc cttctcttca aaccactgcg ccaacgtctg cctggtttct
     9361 ctccgtgtct ttatttccat atgttccctt aattatctgg tcagttaaca ataacaatta
     9421 tctggctata actgataatg cagataactt agctaatcag cttatcaacc tcagcaagag
     9481 gtaaatttgc catctctgca acgtcttccc gagacatccc tttactcaga aaacgcaggg
     9541 cgaattcctg tcttacttcc tgtctaacct cttgtattac ctcctgtctt acctcctgtc
     9601 ttacctcctg ccttcccctc tcttcaaacc actgcgccag cgtcatcata gactcccctc
     9661 ccgtttccct gtctcgcaac acaccataaa acaaatccgc ttgttcagta tgaccgcgtt
     9721 gcagcatata gttttgcatg gcaactaact gacttccgct agtgtaccct tcgtcaatca
     9781 gcgtgaccag ttgctccagc aataacatta agtcgcgctg gcgaatatgc ttttgcagta
     9841 gttcgagaat cgcaatccgc cggtgctgca tgatttcgtc atccggcgtg atggtgatat
     9901 ccaccagcgg gaaagggttg ttgtaaacgc gtcgcgccag ctccggcgag taaaacatat
     9961 caaaccagca cattgagagc ggataaggtg tggcctcgcc ctgataaaac agaatcggca
    10021 ccaccagcgg cagcttatcg tgatccgcct ccagatgccg gtgcatggcg gcaatggcat
    10081 agcgcatcat gcgaaaggtc attttcttat ccggcttgct ttggtgttca atcacaacat
    10141 gcagataacc cgtactaccc tgcatctgta cggaatagag cacgtcagtg ctgtgccctt
    10201 tcaggctttc ttcaataaaa ctccccgact caagatgcag cgtgtcgagg tcacacagtt
    10261 cgcgtagctc cgctggcaaa tggatatcca gaaagtcgcg agccgtttcc gcatgcatta
    10321 aaaattgttt aaacaccgca tcatgcggtg tggtactcgg tgcatccatc tcccctgcct
    10381 tccgtgttgt cttgcgtgaa ggcagtatcc agtcaaggtg tgccgtcgtc agccgcctct
    10441 ttagtgttta ccgagcagcg ttcagataaa tttcaattgg ttacaggcgt tacatggcac
    10501 gcttcggcac ggtacgcaaa ctgctgatgc aaatgccgtc agatgagtag acactaaaca
    10561 aaaatcgggc aatactgcgt gagaatttcc tcaaagcagg catcgcctgc ttcgttaacg
    10621 acagggtaga aaggtagaag ttatgattcg cacgatgctg cagggcaaac tccaccgcgt
    10681 gaaagtgact catgcggacc tgcactatga aggttcttgc gccattgatc aggattttct
    10741 tgacgcagcc ggtattctcg aaaacgaagc cattgatatc tggaatgtta ccaacggcaa
    10801 gcgtttctcc acctatgcca tcgcggcaga acgcggttcg agaattattt ctgtcaacgg
    10861 tgcggcggcc cactgcgcca gcgtcggcga tattgtcatc atcgccagct tcgttaccat
    10921 gccagatgaa gaagctcgca cctggcgacc caacgtcgcc tattttgaag gcgacaacga
    10981 aatgaaacgt accgcgaaag cgattccggt acaggttgcc tgattgttat ccctgcggct
    11041 ggttactcac cagccgcgac atcgtctcca gcgaatctgt tcttaagata taaagtcgtt
    11101 ttagtaacaa cggattatcc cccggtttta ctttgccttt catggtcgtc acagccaggt
    11161 gaaatccggc ttcttttgct gccttcacgg ctttgtcatt aaatccgcca aatggataag
    11221 aaagatacaa aacatgtgga ttaaattgcg ccagagcgcg gcgtgaacgt gcaaaatcaa
    11281 acagaatatt gtgctcacta cggctcagca atataggccg ccgataacca tctatccgat
    11341 gcaaaaaatg agtatgtgac tggaaatcaa atacatcgcg aatttcgtta agttcagaaa
    11401 cgctcataaa ttgcagcgat tttgggttcc atttctgcgg gtgacgtttg atgcgcgagg
    11461 taacaataaa cgccgtcgcc ttcatgccat attgtttcaa cacaggatac gcatagcggc
    11521 tcaccgactt gaggccatca tcaaaggtaa tcaccaccgc tcgcgcaggg agattgatct
    11581 tattcttcac gtaaccttcc agctgcgcca tgctcagtgt cgcgtatccc ctgtcgcgca
    11641 gccaggccat ctggttattg aaagcgcgta ccgaggtggt cgtcgaagta tggcgaaaac
    11701 gggtgttttc ttcatcgcgc aaaatatggt gataggttag caccggcagg ccattatcgg
    11761 gttgggcatc cagcgcgctg atataggcca gtcgatcgcc aatacggatc tgataccagg
    11821 tttgatttaa cctgtctttc agtttatgca aaatcgggta gcgcaaattg tccgccagta
    11881 ctccaaatgg cgcactgccc acactcggcg cgttatagac ctgcgtatct ttccaggtaa
    11941 ctaagttctg attactcagc ggcttgttga ggtcacccaa accgtcttca actttttgtc
    12001 gcccctgaac cggctcgaga tgccctttat cgataaaccc tttgccaagg ccaaaattaa
    12061 atacgtaata acttgcggca gtgggctcca cggcaatgat ttgtccggcc cgaatattcc
    12121 ccaccgtcac catcttgtca ccaatttgcg cccagaccgc ggcattttcg atggtttgca
    12181 tataacgggc aggtaacgcg gcactgacac ttgcggtaaa cagcatcagc aggagaataa
    12241 cagcttgttt gtacatgaaa aaataaccga gggtgaaaca acgcttttat tgtagcaaaa
    12301 gcgtcatcag aatcgcgggt taatactcat acaaattatg tttgaggacg aaaggcggat
    12361 ttttttgttg ctggtgccaa agactactca cctccggcgc acccagttcg acaatacgct
    12421 cgcgaaacgc tgaactggtc atggtttcac ggcaagccat catctgttca attaacggta
    12481 acgtgacacc agaaatcact tcgcaacggg agtgtttgtg gcttaataat gaagccacgc
    12541 ggtacggtgg cgctccggct atatcggtta agaaaataac gccttcacca gagtccgttt
    12601 catgcaaggc atcgcacatc atgcggctga gcatattaga gcttaatccg cgccagaaat
    12661 tcacggcccg gcactgaaga agtgccccat gttttttctc cagcgcatcc agtatctctt
    12721 gcgcccggtc atcgtgacag gtaattaccc aacctaacat cgccttcctc cttagccgaa
    12781 aatcagtcta ccctgaccat tgttgataaa gggtgatagc cgtcaaaact cctctccccc
    12841 aaatccagag gagaggaaat agccttagct acgcaaacca cgtccacgtt ggatcagcga
    12901 ccaacagatc aaataaaacg ccacaataaa gaccaccagt acgccaaagg tagtgaccag
    12961 cggaacatca ttgataccga ggaagccgta gcggaaacca ctgatcatat aaacgattgg
    13021 gttcaggtgc gacagccctt gccagaacgg cggcaacaaa gtcagggagt aaaacacccc
    13081 gcccaaatac gtgagtggcg ttaacacaaa ggttggcacc aggctgatgt catcgaacgt
    13141 tttagcaaac acgccgttca gcaaacccgc aagggagaat agcaccgcag tgagcaccag
    13201 ggttaaggca acgaataccc acgaatgcac ctgaaacggc acaaaaaaca gtgaaattgc
    13261 cgtcaccaga ataccaacaa acagaccacg cgccacgcca ccaccgacat atccggcaat
    13321 aatgacatga gtcggaaccg gcgctaccag cagctcttca atattacgct ggaacttggc
    13381 accaaaaaat gatgacgcga cgttagcgta ggcgttggtg atcaccgaca tcatgatcag
    13441 ccccggtacg atgaactgca tgtagctgaa gccatgcata tcgccaatac gcgaaccaat
    13501 caggttaccg aagataataa agtaaagggt catggtgatg actggcggca ccagcgtctg
    13561 cacccagata cgcataaagc gatggatctc tttcgcccag atgcttttta gcgccaccca
    13621 gtaaagatgc atcatgtgcg atctccttgt ttttcattaa ccagtgaaac aaacagctct
    13681 tccagacggt tagctttgtt acgcatactt aatacctgaa tgccctgctc acttaactgc
    13741 gtaaatacgc tgttgatgcc ctgctcacgc agcacttcaa cttccagcgt ggcggtatct
    13801 accagtcgat actgatagcc atcgagcttc ggtaacggac ttttcggtgc gagatcgaga
    13861 ataaaggttt ctgatttcag cttcgccagc agcgccttca tcgaagtatt ttccaccaac
    13921 tcaccgtgtt gaataatgcc gatattgcgg cacagcattt ctgcttcttc caggtagtgt
    13981 gtggtgagaa tgatggtggt gcctttgtcg tttaaatcct tcaaaaagcc ccacattgag
    14041 cggcgaagtt caatatccac gcctgcggtc ggttcgtcga gaatcagtag tttaggttca
    14101 tgcattaacg cacgggcaat cattaaacgg cgcttcatcc cgccagataa catacgcgca
    14161 cgttcgttgc gttttcccca tagatcgagt tgtttaagat acttttcgct gcgaatgtac
    14221 gcttctttgc gctccacacc gtagtaccct gcctgattca ccacaatttg ctgcacggtt
    14281 tcaaacgggt tgaagttaaa ttcctgtggc accagaccca actgacgttt agcgtttacg
    14341 acatctttct cgagatcgta accaaatacg ctgacccgcc cggaggtttt atttaccaga
    14401 gagctgataa taccgatagt ggtcgatttt ccggccccgt tcggcccgag aagcgcataa
    14461 aaatcacccg cttcgacctg caaatcgatt ccacgaagcg cctgaacgcc gcctggatag
    14521 gtttttttaa gctgttgaag ttccagtgca atggtcataa atttttactt accttacgtt
    14581 cttacacttt atctgtggtt taaatcgtcc cggagttgcc ctatattagc caaacgtaat
    14641 tatttggtta caggtcgtta acctccatga aagacataga tacactcatc agcaacaatg
    14701 cactatggtc aaaaatgctg gtggaagagg atcccgggtt ttttgagaaa ctggcacaag
    14761 cgcaaaaacc gcgctttcta tggattggat gttccgacag tcgcgttcct gcagaacgtt
    14821 taaccggtct tgagccgggc gaactctttg ttcaccgtaa tgttgctaac ctggtcattc
    14881 acaccgacct gaactgcctt tccgtggttc agtatgcagt ggatgtactc gaagttgaac
    14941 acattattat ctgtggccac tacggttgcg gcggcgtaca agccgcagtt gaaaacccgg
    15001 aactggggct tatcaacaac tggctgctgc atatccgcga tatctggttc aaacatagct
    15061 cattgctcgg cgaaatgccg caagagcgcc gtctggatac cttgtgtgaa ctgaacgtca
    15121 tggaacaggt gtataacctg ggccactcca ccattatgca atcagcgtgg aaacgcgggc
    15181 agaaagttac cattcacggc tgggcctacg gcattcacga cggcttgctg cgtgatctgg
    15241 atgtcacagc gactaaccgc gaaacccttg agcaacgtta ccgtcacggg atctccaacc
    15301 tcaagctgaa acacgccaac cacaaataaa aatgccatgc cggatgcaac acatccggca
    15361 acttcacact tactcgtcca gcagaatcac tttgccgata tacggcagat gacggtaacg
    15421 ctgtgcgtaa tcaatgccgt aacccaccac aaactcatcc gggatcgaga aaccgataaa
    15481 ttctaccggg acgttcactt cacgacggga cggtttatcc agcagcgtac aaatcgccaa
    15541 cgacttcggt tcgcgcaggc ttaagatctc acgcactttc gacagtgtat tccccgagtc
    15601 gatgatatct tcaacaatca gcacgtcctt gccacggata tcttcatcca gatctttgag
    15661 gattttcaca tcacgggtgg tggacatgcc gctaccgtag ctggaggcgg tcataaagtc
    15721 gacttcatga gatacctgaa cttcacggca caggtccgcc ataaacataa atgagccacg
    15781 cagcagaccc accagcacca tatcgctgcc gctgtctttg taacgctcag taatctgacg
    15841 acccagttcg gcgatacgcg ctttaatctc cgcttcgggg atcattactt ctacagtatg
    15901 tttcatatct ataaccatat gatttaaaaa caaatcactt cgcacggg
//
LOCUS       DAFGPF010000112        15766 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFGPF010000112 DAFGPF010000000
VERSION     DAFGPF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15766
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.112"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..669
                     /locus_tag="LSX49_004015"
     CDS             <1..669
                     /locus_tag="LSX49_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBL7170355.1"
                     /translation="DGRDYDPDVLQKAVNDAVANIPQPADGKSLTPDDVRPMLEQMVK
                     EAVSHIHVPRDGRDYDPDVLQKAVLDAVSALPAPQDGRDATALEILPAIDDQKSFPRG
                     TYATHQGGLWRAYEKTHGMRGWECLVDGVADIDVSMTGERLFSVVVRQSSGQRTEKTF
                     SLPVMLYRGVFRAGETYHPGDTVTWGGSLWHCNSMTEDKPGEAHSSAWTLAAKRGRDA
                     GGGK"
     gene            666..992
                     /locus_tag="LSX49_004016"
     CDS             666..992
                     /locus_tag="LSX49_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL7170356.1"
                     /translation="MTALLTLEEIKAHLRVDHDADDDMLMDKVRQATAVLLAYIQGSR
                     DKVIREDGELIPGEALTRMKGAAMRLTGMLYRNPDLAEREELLQGELPFSVSVLIYDL
                     RCPTVL"
     gene            1002..1352
                     /locus_tag="LSX49_004017"
     CDS             1002..1352
                     /locus_tag="LSX49_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL7170357.1"
                     /translation="MAISAGRLTQMISVLNPVLTRNAAGEMTEEWVSCGKIHADIRGR
                     SSRERMQSGAEMAQAEIRIWVRGQSGREITAASRLHVLSGPWRDRILNVVGLPVPDAT
                     GGRLEILCRLGGEK"
     gene            1349..1795
                     /locus_tag="LSX49_004018"
     CDS             1349..1795
                     /locus_tag="LSX49_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL7170358.1"
                     /translation="MIETLLDFSGLEDISRDLQLLSGAENNRVLREATRAGANVLKEE
                     VVSRAPVRRGKLRRNVVVLSRRSRDGGMESGVHIRGVNPDTGNSDNTMKADNPRNAFY
                     WRFVEMGTVNMPPHPFVRPAFDVRSEQAAQVAIARMNRAIDEVLRR"
     gene            1792..2136
                     /locus_tag="LSX49_004019"
     CDS             1792..2136
                     /locus_tag="LSX49_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3168 domain-containing protein"
                     /protein_id="HBL7170359.1"
                     /translation="MTEADLYPHLAHLAGGQVYPYVVPLLDGRPSVALPWVVFSLISS
                     VSADVMGGQAESSVSVQIDVYAGTVTQARQIRQDAREAIMLLAPGSVSEMQDYIPENR
                     CYRATLEFQVTV"
     gene            2203..2919
                     /locus_tag="LSX49_004020"
     CDS             2203..2919
                     /locus_tag="LSX49_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin domain-containing protein"
                     /protein_id="HBL7170360.1"
                     /translation="MSALYERSQLTQVMISSAPATAETMDKAEYLRLDCTIKEVQFTA
                     GQKQDIDVTTLCSTEQENINGLGASSEISMSGNFYLNQAQNALRDAYDNDALYAFKVL
                     FPSGKGFKFLAEVRQHTWSSGTNGVVAATFSLRMKGKPVSFVVPLAFVKNLDKTLTVN
                     TGALLTMSVSANGGTPPYKYAWKKDGQPVDGQTTDTFSKPGAQSADAGKYTCVVTDSA
                     EKAQSVTSVECTVTVSAAAG"
     gene            2934..3308
                     /locus_tag="LSX49_004021"
     CDS             2934..3308
                     /locus_tag="LSX49_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HBL7170361.1"
                     /translation="MKKDLKTLALARLSGFRHKTVKVPEWGNVSVVLREPSAEAWYLW
                     QEVLNGDGEDDDTLSVVAKTRRNLEADVTLFCDVLCDTDLQRVFAPDDREQVLAVYGP
                     VHARLLRQALELIADAESARKK"
     gene            3404..3613
                     /locus_tag="LSX49_004022"
     CDS             3404..3613
                     /locus_tag="LSX49_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4035 domain-containing protein"
                     /protein_id="HBL7170362.1"
                     /translation="MWMEFDRVSPLGDERGDIRNAQIVKAVFGAQGMNVALKDAMLCW
                     GEDEDKPEVDPFAALEDALSFAAQS"
     gene            3661..6903
                     /locus_tag="LSX49_004023"
     CDS             3661..6903
                     /locus_tag="LSX49_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL7170363.1"
                     /translation="MATLRELIIKISANSQSFQSEIQRASRMGSEYYRTLQNGGRQAA
                     AVARVQRRALAELNSQLTEIRASAAGTAGAFAGAFATGHLISLADEWSSVNARLKQAS
                     QSSDEFSSSQKVLMDISQRTGTAFSDNAALFARSAASMREYGYSADDVLKVTEAISTG
                     LKISGASTAEAGSVITQFSQALAQGVLRGEEFNSVNESGDRIVRALAAGMGVARKDLK
                     AMADDGKLTADKVVPALISQLGVLRDEYAAMPETVSDGITKVENAFMAWVGGANEASG
                     ATKTLSGVLNGVAGNIDNVATAAGALVAVGVARYFGNMASGAVSATAGLVTAARNEVA
                     LAEAQLRGTQIATARARAAVYRAQQAVAAARGTEMQIAVEARLAATQERLNRNIAART
                     AAQNELNSTTAVGSRLMTGALGLVGGVPGLVMLGAAAWYTLYQNQEQARESARQYALT
                     IDEIAHKTPSMSLPEASDNEGRTRAALAEQNRLIDEQASRVKSLQEKIAGYQYVLANP
                     GWTTGDGFMINHLTSVKTVTEGLSQATEQLAVEQSRLAQMQEKAQSIQDVLAGLEDRR
                     VALIRQQAAEQNKVYQSMLVMNGQHTEFNRLLGLGNELLQQRQGLVNVPLRLPQATLD
                     DKQQSALTKTERELALSRLKGEEKERARLGYAADDLGFVGDSYQEARQRYISNALEAW
                     RNNEANKPKSRGGKSETEKAEDSFSRLLKQQKEQLALAGQNTELAKLKYQTAQGELKT
                     LTEMQKQELLRNAALIDQQKIREQLRSREETLKNDNVAARASNEAELLGYGQGERARE
                     RMRELQQIRDSFRQKDADLQSQYQTGDISEDFYRQARAQNAQYLSERLKDQAAFYAES
                     DAQRADWQKGLQEGLSNWVDNASDYASQAAQLATEGISGMVNNITEMLNGNKVEWRNW
                     ASSVLQEISKVLMNAAIVNGIKTAANGMSGAGGFIGSIGDWLGGAVANAKGGVYTSAN
                     LSAYSNSIVDTPTYFAFAKGAGLMGEAGPEAIMPLTRAADGSLGVRAVGSMNGSAGLV
                     YSPVYHIAIQNDGANGQIGAEAAGSLVQLIDQRVQAVMLSMRRDGGMLSG"
     gene            6896..7237
                     /locus_tag="LSX49_004024"
     CDS             6896..7237
                     /locus_tag="LSX49_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7170364.1"
                     /translation="MAEIKTLHLVPREGMQVSEKPSVVRVRFGDGYEQRRPTGLNARL
                     KTFQAVFRVTDEPTRRWLDEFLSWHGGYRAFLWRPPKHNLTVRVVCREWSVTDNARHS
                     DFSCTIEQVVN"
     gene            7237..7935
                     /locus_tag="LSX49_004025"
     CDS             7237..7935
                     /locus_tag="LSX49_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HBL7170365.1"
                     /translation="MQDIREESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNE
                     KGEPVTWQGRQYQAYPIDGSGFEMSGKGSSARPSLTVSNLFGLVTGMAEDLQSLVGAT
                     VVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSQLTAMTASFVLATPTETDG
                     ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCELRRNV
                     GNFGGFLSINKLSQ"
     gene            7946..8689
                     /locus_tag="LSX49_004026"
     CDS             7946..8689
                     /locus_tag="LSX49_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7170366.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVISTSEGEWYIPCVNISAEPE
                     AYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGDIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGTEMPDFHREDDWWRNGQNLYLDNMAVT
                     GFYRVPLSSAQAGDILLCCFGASVPNHAAIYCGNGELLHHLPEQLSKRERYSEKWQRR
                     THSVWRHRHWHASAFTGIYNDLAAASACM"
     gene            8635..9267
                     /locus_tag="LSX49_004027"
     CDS             8635..9267
                     /locus_tag="LSX49_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HBL7170367.1"
                     /translation="MCLHGDLQRFGRRLSLYVNTAAEAIRALSLQVPGFRRQMNEGWY
                     QIRIAGYDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVGSFFTA
                     GASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTY
                     FSSLDNMIAQGNPMPVPYGEMLVGSRRISQDISTRDEGGGGTVVVIGRQG"
     gene            9610..13083
                     /locus_tag="LSX49_004028"
     CDS             9610..13083
                     /locus_tag="LSX49_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HBL7170368.1"
                     /translation="MGKGGGKAHTPREAKDNLKSTQMMSVIDAIGEGPIEGPVKGLQS
                     ILVNKTPLTDTDGNPVIHGVTAVWRAGEQEQTPPEGFESSGAETGLGVEVTKAKPVTR
                     TITSANIDRLRVTFGVQSLVETTSKGDRNPASVRLLIQLQRNGNWVTEKDVTINGKTT
                     SQFLASVILDNLPPRPFNIRMVRETADSTTDQLQNKTLWSSYTEIIDVKQCYPNTAIV
                     GLQVDAEQFGGQQMTVNYHIRGRIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYAIGQYCDQTVPDGFGGTEPRMTFNAYLAQQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDVVWPYTNSDVVVDDNGVGFRYSFSAL
                     KDRHTAVEVNYTDPQNGWQTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLW
                     VIKTELLETQTVDFTLGSQGLRHTPGDIIEICDNDYAGTLTGGRVLSIDAATRTLTLD
                     REVTLPETGTSAVNLINGSGKPVSVDITAHPAPDRIQVSTLPDGVETYGVWGLSLPSL
                     RRRLFRCVSIRENTDGTFAITAVQHVPEKEAIVDNGARFEPQSGSLNSVIPPAVQHLT
                     VEVSAADGQYLAQAKWDTPRVVKGVRFSLRLTSGKGTDARLVTTAITADTEHRFSGLP
                     LGEYTLTVRAINSYGQQGEPATTTFRIAAPAAPSRIELTPGYFQITATPHLAVYDPTV
                     QFEFWFSEKRIADIRQVETAARYLGSALYWIAASINIKPGHDYYFYIRSVNTVGKSAF
                     VEAVGRASDDAEGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITNVSNEI
                     TQTVNKKLENQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIENTP
                     AGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITSGGNPPA
                     FSLTPDGRLTAKNADISGNVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVGKA
                     FPRDSRAPERWPSGTITVRVYDDQPFDRQIVIPAVAFSGAKHEKEHTDIYSSCRLIVR
                     KNGAEIYNRTALDNTLIYSGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLVVV
                     MKKATAGITIS"
     gene            13151..13750
                     /locus_tag="LSX49_004029"
     CDS             13151..13750
                     /locus_tag="LSX49_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family protein"
                     /protein_id="HBL7170369.1"
                     /translation="MRKLCAVILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPG
                     SDDLNGINVKYRYEFTDALGLITSFSYANAEDEQKTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVTIDLAYEGSGSGDWRTDAFIVGIGYRF"
     gene            13902..15374
                     /locus_tag="LSX49_004030"
                     /pseudo
     CDS             13902..15374
                     /locus_tag="LSX49_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
BASE COUNT         3641 a         3922 c         5047 g         3156 t
ORIGIN      
        1 gacggtcgtg actatgatcc cgatgttctg cagaaggcgg tgaatgatgc ggtcgcaaat
       61 attccgcagc cggcagacgg taaaagtctc accccggatg atgtgcgtcc gatgcttgaa
      121 cagatggtga aggaggcggt aagccatatt catgttccgc gtgatggtcg tgactacgat
      181 ccggatgttc tgcagaaggc ggttctggat gcggtgagtg ccctgccggc tccgcaggac
      241 gggcgtgatg ccacggctct ggaaatactc cccgccattg acgatcaaaa atcctttccc
      301 cggggcacgt atgccacaca ccagggcgga ctctggcggg cgtatgaaaa aacgcacggg
      361 atgcggggat gggaatgcct ggttgacggg gtggcggata ttgacgtcag catgacgggt
      421 gagcggttgt tctctgtggt ggtccggcag agcagtggcc agcgtacgga aaaaacattt
      481 tccctgccgg tgatgctcta ccgcggtgtg ttcagagccg gtgaaaccta ccaccccggc
      541 gatacggtga cgtggggggg ctcgctgtgg cactgcaaca gtatgaccga agataaaccc
      601 ggagaagctc attcatcagc ctggaccctg gctgcaaaac gtgggcggga tgcaggaggc
      661 ggaaaatgac ggcattactg acactggaag agatcaaggc acatctgcgt gtcgaccatg
      721 acgcggatga tgacatgctg atggacaagg ttcgtcaggc taccgccgtg ctgctggcct
      781 acattcaggg cagccgggat aaagtgatcc gtgaggacgg tgaactgatc ccgggcgagg
      841 cattaacccg gatgaagggg gctgccatgc gactgaccgg gatgctgtac cggaatccgg
      901 atcttgcgga gcgggaagaa ctgcttcagg gggagctgcc gttttctgtt tccgtgctga
      961 tttacgattt gcgttgtccg acggtgttat gaggaggggg aatggcaata tctgcaggtc
     1021 gtctgacaca gatgataagt gttctgaacc cggtgttaac ccgtaacgct gccggagaaa
     1081 tgacggaaga atgggtgtca tgcgggaaaa ttcatgcgga tatccgaggc aggagcagcc
     1141 gggagcggat gcagtccggt gcggaaatgg cgcaggcgga aatccgcatc tgggtgcgcg
     1201 gtcagtccgg tcgggaaatc acggcagcgt cacgacttca tgtgctgagt ggtccatggc
     1261 gtgaccggat cctgaacgtt gtcgggctgc ccgtgccgga tgcgaccggc gggcgtctgg
     1321 aaattctctg tcggctggga ggggaaaaat gatcgaaacc ctgctggatt tttcggggct
     1381 ggaggacatc agccgcgatt tgcagcttct gagtggtgcg gaaaataacc gggtgctgcg
     1441 tgaggcaacc cgtgcgggtg cgaatgtgct gaaagaagaa gtggtgtcac gggcaccggt
     1501 acgcagggga aaactgcgcc gcaatgtggt ggtcctttcc cggcgctccc gcgatggcgg
     1561 gatggaatcc ggtgtccata tccgtggtgt taatccggac accggtaaca gcgataacac
     1621 catgaaggcg gataacccgc gcaatgcttt ctactggcgg tttgtggaaa tggggaccgt
     1681 gaatatgcca ccgcacccgt ttgtgcgccc ggcgtttgat gtgcgcagtg aacaggcagc
     1741 tcaggtggcg attgcgcgga tgaaccgggc cattgatgag gtactgagac gatgacggag
     1801 gcggatttgt atcctcatct ggcgcatctt gccggcgggc aggtgtaccc gtatgtggtc
     1861 cccctgctgg atggcaggcc gtcggtggcg cttccgtggg tggttttcag cctgatttca
     1921 tcggtgtctg cggacgtgat gggcgggcag gcggagtcct cagtgtcggt gcagatagac
     1981 gtttatgccg ggactgtgac gcaggcgcgt cagatacgtc aggacgcccg tgaagccata
     2041 atgctgctgg ccccgggatc cgtcagtgaa atgcaggact atattccgga aaaccgctgt
     2101 taccgtgcaa ccctggagtt tcaggtcacg gtgtgacttt ttcttttttt ctacaaaacc
     2161 cataccccgc cgcgtgcggg ttttttatta tcaggaggca gaatgtctgc tttgtatgaa
     2221 cgctcacagc tgacgcaggt gatgatttca tctgccccgg cgactgctga aactatggat
     2281 aaggcggaat atctgcgcct ggactgcacc atcaaggaag tccagttcac cgctggtcag
     2341 aaacaggata ttgatgtgac cacgctctgc tccaccgagc aggagaacat caacggtctg
     2401 ggggcgtcgt ctgagatttc catgtcgggt aatttttatc tgaatcaggc ccagaacgcc
     2461 ctgcgtgatg cctatgacaa tgacgcgttg tatgcgttta aggtgctgtt tccgtccggt
     2521 aagggcttta agttcctggc ggaagtgcgt cagcacacct ggtcatccgg taccaacggc
     2581 gtggtggcag caacgttttc actgcgtatg aaaggcaaac cggtgtcctt tgtggtaccg
     2641 ctggcgtttg tgaaaaatct ggataaaaca cttaccgtga atacaggtgc gctgctgaca
     2701 atgtcagtca gtgccaacgg gggaacgccg ccgtataaat acgcctggaa gaaggatggt
     2761 cagccggttg acgggcagac gacagacacc ttcagtaagc caggtgcgca gtccgctgat
     2821 gcggggaaat atacctgcgt ggtgaccgat tcggcagaga aagcacagag tgtgacgtct
     2881 gttgaatgca ccgtgacagt gagcgcagcc gccggataag gggatgggtc atcatgaaaa
     2941 aggatctgaa aacgctggcg ctggccagac tgtcagggtt tcgtcataaa acggtgaagg
     3001 tgccggaatg gggtaatgtc agcgtggtgc tgcgggagcc ttcggcagag gcctggtatc
     3061 tgtggcagga agtgctcaat ggtgatggag aggatgacga taccctgtcg gtggtggcga
     3121 aaacccgccg taacctagaa gcggatgtga cgctgttctg cgatgtcctg tgtgatacgg
     3181 atctgcagcg ggtgttcgct ccggacgacc gtgagcaggt gctggccgtc tatggtccgg
     3241 tacatgcccg gttgctgcgt caggcactgg aactgatcgc tgatgcagag tcggccagaa
     3301 aaaagtagcc cgcccggaaa ttcgctttct gatgcgactt gcgctccgtc tggggcgcac
     3361 cttatccgaa ctgcggcaca gcctgagtgt gagcgaggcg atgatgtgga tggagttcga
     3421 cagggtatcc ccgctgggtg atgagcgcgg ggatatccgt aatgcacaga tcgtgaaagc
     3481 ggtttttggg gcacagggga tgaatgttgc actgaaggac gccatgctct gctggggcga
     3541 ggatgaggat aagccggagg tggatccgtt tgcggcgctg gaagacgcgc tgagcttcgc
     3601 agcacagtca tgaatgatga gaaccgctga ggcggttttt ttacgcccgg agaaaggtga
     3661 atggcgacgt tacgtgaact gattatcaaa atttcggcaa attcgcagtc attccagtcg
     3721 gagatccagc gggcttcccg catgggcagt gaatattacc ggaccctgca gaatggcggg
     3781 cgtcaggctg ccgcagtcgc ccgggtgcag cgacgcgccc tggctgagct gaacagccag
     3841 ttgacggaaa tccgcgcttc agctgccgga acggcggggg catttgcagg tgcctttgcc
     3901 accggacacc tgatttctct ggccgatgaa tggagttccg tgaatgcccg actgaaacag
     3961 gcgtcgcagt catccgatga attttcgtca tcacagaaag tgctgatgga tatcagccag
     4021 cggacgggca cggcattttc agataatgcg gccctgtttg cccgctcggc agcctcaatg
     4081 cgtgaatatg gttacagtgc tgatgatgtg ctgaaggtga cggaggccat ttccacgggg
     4141 ctgaaaatct ccggtgccag tacggcagag gcgggctcgg tgatcaccca gttcagccag
     4201 gcgctggcac agggtgtgtt acgcggtgag gaatttaatt cggtcaatga aagcggagac
     4261 cggatcgtac gtgcactggc tgcgggtatg ggcgtggccc gtaaagacct taaggcgatg
     4321 gcggacgacg gcaaactgac ggcggataaa gtcgttcctg cgttaatcag ccagctgggg
     4381 gtattgcgtg atgaatatgc cgccatgccg gaaacggtct ctgacgggat cacaaaggtg
     4441 gaaaacgcct ttatggcctg ggtgggtggc gcgaatgaag ccagcggagc gacgaaaacg
     4501 ctctccggcg tgctgaacgg tgttgccggt aatattgata atgtggcaac agccgcgggg
     4561 gcgctggttg ccgtcggggt tgcccggtac tttggcaata tggcctccgg agcggtgtct
     4621 gccacggcag gacttgtgac ggcagcacgt aatgaagtgg cactggcgga agcacagctc
     4681 agggggacgc agattgccac ggcgcgggca agggcagccg tgtaccgtgc acagcaggct
     4741 gtggcggcag cccgcgggac ggagatgcag attgctgtag aagcccgtct ggcggccaca
     4801 caggaacgcc tgaacagaaa tattgctgcc agaaccgcag cccagaatga gctgaacagt
     4861 acaacggcgg tgggctcacg tctgatgact ggtgcgttgg gactggttgg tggcgtaccc
     4921 ggactggtga tgctgggggc agcagcatgg tatacgctgt accagaatca ggagcaggcc
     4981 agggagtcag cgcgccagta tgcactgacg atagatgaaa tcgcgcataa aacgccgtca
     5041 atgtctttgc ctgaagcctc agataatgaa ggacgaacac gggcggcgct ggcagagcag
     5101 aaccggctga ttgatgaaca ggccagccgg gtgaaatccc tgcaggaaaa aatcgctgga
     5161 tatcagtatg ttctggctaa ccctggctgg acaaccggtg acggattcat gataaaccat
     5221 ctgacatcgg tgaagaccgt gacggaaggg ctttctcagg caacagagca gcttgccgtt
     5281 gagcagtccc gtctggcaca gatgcaggaa aaagcgcagt ccattcagga tgtgcttgcc
     5341 gggctggaag accgtcgtgt ggcgttaatt cgtcagcagg cggcagagca gaataaggtg
     5401 taccagtcca tgctggttat gaacggtcag catacggaat tcaaccgtct gctggggctg
     5461 gggaatgaac tgcttcagca gcgtcaggga ctggtgaatg taccgttacg gctgccgcag
     5521 gccaccctgg atgataaaca gcagagcgcc ctgacaaaaa cagaacgtga gctggccctg
     5581 tcccgactga agggggagga aaaagagcgt gcccggctgg ggtatgcggc ggatgacctt
     5641 ggttttgtgg gggattcgta tcaggaggcg agacagcgtt atatcagtaa tgctctggaa
     5701 gcctggcgta ataacgaggc gaacaaacct aaatcccggg gtggaaaatc agagacggaa
     5761 aaagcggaag acagtttttc ccggctactg aagcagcaga aagagcaact ggcactggcg
     5821 ggtcagaata cagagctggc gaagctgaag taccagactg cgcagggcga actgaaaacc
     5881 ctgacggaga tgcagaagca ggaactgctg cgtaacgcgg ccctgattga ccagcaaaaa
     5941 atccgggaac agttgcgatc ccgggaagag accctgaaga atgataatgt ggctgcgcgt
     6001 gcatcaaatg aagccgaact gctgggatac gggcagggag aacgagccag ggaacgcatg
     6061 cgggagttgc agcagatccg tgacagcttc cgccagaagg atgcggacct tcagtctcag
     6121 tatcagaccg gggatatcag tgaggatttt tacagacagg cacgggcaca gaacgcgcag
     6181 tatctgagcg aacgccttaa ggaccaggca gccttttatg ccgaatcgga tgcgcagcgt
     6241 gcggactggc agaaaggctt gcaggagggg ctcagtaact gggtggacaa tgcatccgat
     6301 tacgcctcac aggcagcaca gcttgcgacg gagggtatct cagggatggt gaataacatc
     6361 acggagatgc tgaacggaaa caaagtggaa tggcgcaact gggcctcatc cgtactgcag
     6421 gaaatctcaa aagttcttat gaatgctgcg attgtcaacg gaattaagac ggcggcaaac
     6481 ggtatgtccg gtgcgggagg atttattggc agcattggtg actggctggg cggtgcggtg
     6541 gccaatgcaa aaggcggcgt gtatacctcg gcaaacctga gtgcgtacag caacagcatt
     6601 gtggacacgc ccacgtactt tgcgtttgca aaaggggccg ggctgatggg ggaagccgga
     6661 cctgaagcca ttatgcccct gacccgggcg gcggatggct cgctgggcgt acgcgcggtg
     6721 ggcagtatga acggcagtgc cggtctggtg tattccccgg tctaccacat cgccattcag
     6781 aatgacgggg ctaacggaca gataggggcg gaggcggcag gcagtcttgt gcagctgatt
     6841 gaccagcggg tgcaggcggt gatgctgtcc atgcgacgtg acggaggaat gctgagtggc
     6901 tgagataaaa acgctgcatc tggtcccgcg tgaagggatg caggtgagtg agaaaccgtc
     6961 ggtggtgagg gttcggtttg gtgacggtta tgaacagcgc cgaccgacgg gacttaatgc
     7021 cagactgaag acgtttcagg cggtgttccg ggtgacggat gaaccaaccc ggcgctggct
     7081 ggatgaattt ttatcgtggc atggtggtta ccgtgccttt ttgtggcgac cgccgaaaca
     7141 taacctgacg gtgagggtgg tgtgccggga gtggagcgtc acagataacg ccaggcacag
     7201 tgatttcagt tgtacgattg agcaggtggt gaactgatgc aggatattcg cgaagaaagt
     7261 ctgaacgagt cggttaagtc agagcagtca ccgcgggtgg tactctggga aatcgacctg
     7321 acggtacagg gcggtgagcg gtattttttc tgtaatgagc tgaatgaaaa aggggagccg
     7381 gtcacctggc aggggcggca atatcaggca tacccgattg acggcagcgg ttttgagatg
     7441 agcgggaagg gcagcagtgc cagaccgtcg ctgacggtgt ccaatctgtt cggtctggtc
     7501 accgggatgg cggaagacct gcagagtctg gtgggggcca cggtggtccg ccgccgggtg
     7561 tatgcccgtt ttctggatgc ggtgaatttc gttgcgggca atccggaggc ggacccggag
     7621 caggagctga gtgaccgctg ggtggtggag cagatgtcgc agctgacagc catgacggcc
     7681 tcgtttgtgc tggctacacc gaccgagacg gatggggcgc tgtttcccgg tcgcatcatg
     7741 ctggcgaaca cctgtatgtg ggattaccgg ggagatgaat gcgggtataa cggtcctgcg
     7801 gtggcggatg agttcgacaa ccccaccacg gatatccgta aggacagatg cagcaagtgc
     7861 atgcgcgggt gtgaactgcg caggaatgtc ggcaattttg gcggtttcct ttccattaat
     7921 aaactttcgc agtaaatccc ggtttatgac acagactgaa tcagcgattc tggcgcatgc
     7981 ccggcggtgt gcgcctgcgg agtcgtgcgg cttcgtgata agcacgtcgg agggggagtg
     8041 gtatatccct tgtgtgaata tttctgcaga gccggaggcg tattttcgta tcgcaccgga
     8101 agactggctg cgggcagaga tgcaggggga gattgtggca ctggtccaca gtcatcccgg
     8161 tgggctgccc tggctgagcg aggctgaccg gcggctgcag ataaaaagcg cactgccctg
     8221 gtggctggtc tgccggggtg acattcacaa attccgctgt gtgccacatc tgacaggacg
     8281 gcgctttgag cacggggtga cggactgtta cacgctgttc cgggatgctt atcatctggc
     8341 ggggactgaa atgccggatt ttcatcgcga ggatgactgg tggcgcaacg gtcagaacct
     8401 ttacctggac aatatggcgg tcaccggctt ttaccgggtg cccctgtcct ctgcacaggc
     8461 gggcgatatt ctgctgtgct gctttggtgc ttcggtaccg aaccatgccg ccatttactg
     8521 cggcaacggt gagctgcttc accatctgcc tgaacaactg agtaaacggg agaggtattc
     8581 cgaaaaatgg caacgacgaa cgcattctgt ctggcgtcac cgccactggc acgcatctgc
     8641 cttcacgggg atttacaacg atttggccgc cgcctcagcc tgtatgtgaa cacggcagcg
     8701 gaagccatcc gggcgctgtc gttacaggtg ccgggctttc gccgtcagat gaacgaaggc
     8761 tggtaccaga tacgtattgc cggttatgac acggcaccgg aggcggtgta cgcccgtctt
     8821 cacgaacagc tgggtgaggg aacggtcatc catattgtgc cgcgactggc cggggccgga
     8881 aagggtggac tgcagattgt gctgggggcg gcagccatcg tgggctcttt cttcactgcc
     8941 ggggcatcaa tggcgttatg gggttcagcc ctggcagccg gtggtttttc tgccaccacg
     9001 atgctgtttt cacttggagc cagcatgatt ctgggcggtg tggcccagat gctggccccg
     9061 aaggcaaaaa caccggatta ccgcgcaacg gataacggca gacagaacac gtacttttcc
     9121 tcgctggata acatgattgc ccaggggaac ccgatgccgg tgccttacgg ggaaatgctg
     9181 gttggctccc gccgtatatc ccaggacatc agcacccgtg atgaaggcgg gggcggaacg
     9241 gtcgtggtta tcgggcgaca gggataaaac ataaaaaaat cccgcagtga tcgcggagct
     9301 gcggggacag acaaatgaag atcaatgtta aggagttgtt tttgttactc gggcaaaaaa
     9361 acactaacgc agcgaaatta taagcgccac agtcagtgtg tgaaaatgtg aagatattca
     9421 gaatttttat gccattaccg gttttaacca acaggattat cggtgggcat gaaagaaaac
     9481 cccggtatct gctgataccg gggtttctct ttagcatggc agaaatgtgt ttcatgcttt
     9541 tcgggcgaag gatatccgac ttctgtacgg aatggcaagt ggcggttaat ttattcaggg
     9601 gaaggctgta tgggaaaagg tggcggtaag gcacacacgc ctcgtgaggc gaaggataat
     9661 ctcaaatcca cgcagatgat gagcgtgatt gatgcgattg gtgagggacc gatagaaggt
     9721 ccggtgaagg gactgcagag tattctggtg aacaaaaccc cactgacgga cacggacggc
     9781 aatcccgtga tacacggtgt gacggcggtc tggcgcgccg gggagcagga gcagacacca
     9841 ccggaaggct ttgagtcctc cggagctgaa accggactgg gcgtggaagt gacgaaggca
     9901 aaaccggtga cgcgcaccat tacgtccgcg aacattgacc gcctgcgggt taccttcggg
     9961 gtgcagtcac tggtggagac cacctcaaag ggtgaccgta acccggcatc cgtccgcctg
    10021 ctgattcagt tacagcgtaa cggtaactgg gtgacagaaa aggacgtcac cattaacggc
    10081 aagaccacct cacagttcct ggcctcggtg attctggata atctgcctcc ccggcccttt
    10141 aacatccgga tggtcaggga gacggcggac agcaccacgg accagctgca gaataagacg
    10201 ctgtggtcgt catacaccga aatcatcgat gtgaaacagt gctacccgaa cacggccatt
    10261 gtggggctgc aggtggatgc ggagcagttc ggcggccagc agatgacggt gaactaccat
    10321 atccgcggtc gcatcatcca ggtgccgtca aactatgacc cggaaaaacg cacgtatagt
    10381 ggtatctggg acggcagtct gaaaccggca tacagcaaca acccggcctg gtgtctgtgg
    10441 gacatgctga ctcacccgcg ctacggcatg ggaaaacgtc tgggggcggc ggatgtggac
    10501 aagtgggcgc tgtatgccat cgggcagtac tgcgaccaga cggtcccgga tggtttcggg
    10561 gggaccgagc cgcggatgac ctttaatgcg tacctggcac aacagcgtaa ggcgtgggac
    10621 gttctcagtg atttctgctc tgcgatgcgc tgtatgccgg tatggaacgg tcagacgctg
    10681 acgttcgttc aggaccgccc gtcggatgtg gtgtggccgt acaccaacag cgatgtggtg
    10741 gtggatgata acggcgtggg attccgctac agcttcagtg ccctgaagga ccggcacacg
    10801 gcggtggagg tgaattacac cgacccgcag aacggctggc agacctccac ggaactggtg
    10861 gaagacccgg aagccatact gcgctacgga cgcaacctgc tgaagatgga cgcgttcggc
    10921 tgtaccagcc gcggtcaggc ccaccgtgcc ggactgtggg tgataaagac cgaactgctg
    10981 gaaacgcaga cggtggattt cacgctcggg tctcaggggc tgcggcacac acccggtgac
    11041 attattgaaa tctgtgataa tgactatgcc gggaccctga ccggcggacg tgtcctgtcc
    11101 attgatgctg ccacccgcac cctgacgctg gaccgtgagg ttaccctgcc ggagacaggt
    11161 acatcggcgg tgaacctgat taacggcagc ggtaagccgg tgagtgtgga catcaccgca
    11221 caccccgcgc cggaccggat acaggtcagt accctgcctg atggtgtgga gacatacggg
    11281 gtgtggggac tctccctgcc gtcactgcgc cgtcgcctgt tccgctgtgt ctccatccgg
    11341 gaaaacacgg acggcacctt tgccatcacg gcggtgcagc acgtaccgga aaaagaagcc
    11401 atcgtggata acggtgcccg ctttgagccg cagtcaggtt ccctgaacag cgtcatccca
    11461 ccggcagtgc agcacctgac ggtggaggtg agcgcagctg acggccagta tctggcgcag
    11521 gcgaaatggg acacgccgcg ggtggtgaag ggtgtgcgct tcagtctgcg cctgaccagt
    11581 ggtaagggaa cggatgccag actggtgacc accgccatca ccgcagacac ggagcaccgt
    11641 ttcagcggcc tgccgctcgg ggaatacacc ctgacggtgc gggcgataaa cagctatggc
    11701 cagcagggtg aacctgccac caccaccttc cggattgccg caccggcagc accgtcgcgg
    11761 attgagctga cgccgggcta ttttcagata accgcaacgc cacatcttgc cgtttatgac
    11821 ccgacggtac agtttgagtt ctggttctcg gaaaagcgga ttgcggatat caggcaggtt
    11881 gaaaccgcag cccgctatct tggctcggcg ctgtactgga tagctgccag tatcaatatc
    11941 aaaccgggcc atgattatta tttttatatc cgcagtgtga atactgttgg caaatcggca
    12001 ttcgtggagg ctgtcggtcg ggcgagcgat gatgcggaag gttacctgga ttttttcaaa
    12061 ggagaaatcg ggaaaacaca tctggcccag gagctgtgga cgcagattga taacggtcag
    12121 cttgcgccgg acctggctga aatcaggacg tccattacga atgtcagcaa tgaaatcacg
    12181 cagaccgtca ataaaaaact ggaaaatcag agtgcggcaa tccagcagat acagaaagtt
    12241 caggttgata caaataataa cctgaacagc atgtgggccg tgaaactgca gcagatgcag
    12301 gacggacgcc tttatattgc gggtatcggt gccggtattg agaatacgcc agcaggaatg
    12361 cagagtcagg tgctgctggc ggcagacagg attgcgatga ttaatcctgc gaatggcaac
    12421 acaaagccga tgtttgttgg tcagggcgat cagatattta tgaatgaagt gttcctgaaa
    12481 tatctgacgg ctcccaccat taccagcggc ggtaatcctc cggcattttc cctgacaccg
    12541 gacgggcggc tgacggcgaa aaatgccgat atcagcggta acgtgaatgc gaactccggg
    12601 acgctcaaca acgtcacgat taacgagaac tgtcgggttc tgggaaaatt gtccgcgaac
    12661 cagattgaag gcgatctcgt taaaacagtg ggcaaagctt tcccccggga ctcccgtgca
    12721 ccggagcggt ggccatcagg aaccattacc gtcagggttt atgacgatca gccgtttgac
    12781 cggcagattg ttattccggc ggtggcattc agcggcgcta aacatgagaa agagcatact
    12841 gatatttact cctcatgccg tctgatagtg cggaaaaacg gtgctgaaat ttataaccgt
    12901 accgcgctgg ataatacgct gatttacagt ggtgttattg atatgcctgc cggtcacggt
    12961 cacatgacac tggagttttc ggtgtcagca tggctggtaa ataactggta tcccacagca
    13021 agtatcagcg atttgctggt tgtggtgatg aagaaagcca ctgcaggcat cacgattagc
    13081 tgaattttat aacccagata cgggcgccag aaatggcgcc ttttttattg cagaaaagcg
    13141 agaggtaatt atgcgtaaat tatgtgctgt tattttgtcc gcagtagtct ggcaggtcgc
    13201 cgctgctacg ccagcgagtg cagcagaaca tcagtccacg ctgagcgcgg ggtatctcca
    13261 tgcctcgacg aacgttcccg gtagtgatga tctgaacggg attaacgtga aataccgtta
    13321 tgagtttacg gacgcgctgg ggctgattac gtccttcagt tatgccaatg ctgaggatga
    13381 gcaaaaaacg cgctacagcg atacccgctg gcatgaagat tccgtgcgta accgctggtt
    13441 cagcgtgatg gcggggccgt ctgtacgcgt gaatgaatgg ttcagcgcgt atgcgatggc
    13501 gggtgtggct tacagccgtg tgtcgacttt ctccggggat tatctccgcg taactgacaa
    13561 caaggggaaa acgcacgatg tgctgaccgg aagtgatgac ggtcgccaca gcaacacgtc
    13621 tctggcgtgg ggggctggcg tgcagtttaa cccgaccgaa tccgtgacca ttgaccttgc
    13681 ttatgaaggt tccggtagtg gcgactggcg aacggatgca tttattgttg gtatcggata
    13741 ccgtttctga caacagacgc cgatttatct tctgtaaata ttgttatgat acgcaggttc
    13801 atccacctta tggggtgaac tgcgtttgag gaaacgtaaa gttacactgt cctgaagccc
    13861 gtggcgtcac tgctgcgggc tttttttatt ggtggaaaag tatgacagta aaaatttctg
    13921 gcgtgcttaa agatggcaca ggaaaaccag tacagaactg caccattgtg ctgaaggcca
    13981 gacgaaccag cagcacggtg gtggtgaaca cggtggcctc tgaaaatccg gatgaagccg
    14041 gacgttacag catggatgtt gagcatggtc agtacagcgt caccctgctg gttgaaggtt
    14101 ttccgccttc acatgccggg accattaccg tctatgaagg ttccagacca ggtacgctga
    14161 atgattttct cggtgccatg acggaggatg atgtacgacc ggaggcactg cgccgctttg
    14221 agcagatggt agaagaggtg tcacgtaacg cctccgcggt tgcacagaat acggcagccg
    14281 cgaaaaaatc agccagcgat gccagtgcat cagccagcga ggcggcaact catgcaaccg
    14341 atgctgcagc ctcatcacgt gccgccagca cgtcagccgg acaggccgcg tcgtcggctc
    14401 agtcagcgtc ttccagcgca ggaacggcat cgacaaaggc ccgtgaagca gcaaaaagtg
    14461 ctgctgctgc agagtcatca aaaagcgcgg cagctaccag cgccagtgcc gcgaaaacgt
    14521 cagaaacgaa tgccgcagca tcacaaaaat cggcagccac ttctgcatcc acagcgacca
    14581 cgaaggcgtc agaagctgcc acctcggcac ggggtgcggc ggcctcaaaa gaggcagcga
    14641 aatcttcaga aacgaatgca tcatcaagtg ccagtagtgc agcttcctcg gcaacggcgg
    14701 caggaaattc cgcgaaggcg gcaaaaacgt ccgagacgaa cgctaagtct tctgaaacag
    14761 cagcgggaca gagcgcctca gctgcggcag gttcaaaaac agcggctgca ttatctgcca
    14821 gtgccgcgtc aacaagtgcc gggcaggcct cagccagtgc caccgccgcc ggaaaatcgg
    14881 cagaaagcgc cgcatcatcc gcttcaacag ccacaacgaa ggctggcaaa gccactgagc
    14941 aagccactgc agcagcgagg tctgcttctg cagcaaaaac ctctgaaaca aatgcaaaga
    15001 cttcagcaga caatgctgct tcctctaagg cggcagccgc atcgtcagcc agttcagcgg
    15061 cgtcatcggc atcatctgcg tctgcttcaa aagatgaggc gaccagacag gcgtcagcag
    15121 caaagggcag cgccacgacg gcatccacga aggcgacaga ggcagctggc agtgcgacgg
    15181 cggcagctca gagcaaaagt acggcggaat ccgcggcaac gcgcgccgag acagcggcaa
    15241 aacgggcaga ggatattgca tccgccgtgg cgcttgagga tgcgagcacg acgaaaaagg
    15301 ggatagtaca gctcagcagt gcgaccaaca gcacttccga gtcactggcg gcaacgccaa
    15361 aagcggttaa ggcggtaatg ggtgaaacga acaagaaagc gcccttaaat agtcctgcac
    15421 tgaccggaac gccaacaaca ccaactgcgc gacagggaac gaataatacc caaatcgcaa
    15481 gcacggctta tgttatggct gcgatcgctg ccctcgtgga ctcgtcgcct gacgcactga
    15541 atacgctgaa cgagctggct gcggcgttgg gcaacgaccc gaattttgcg accaccatga
    15601 ctagcgcgct tgcgggtaag caaccgaaag atgccaccct gacggcgctg gccgggcttg
    15661 ctactgcggc agacaggttt ccgtatttta cggggaatga tgttgccagt ctggcaaccc
    15721 tgacaaaagt tgggcgggat attcttgcga aatcgaccgt tgccgc
//
LOCUS       DAFGPF010000113        15260 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFGPF010000113 DAFGPF010000000
VERSION     DAFGPF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15260
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.113"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            70..1359
                     /gene="uraA"
                     /locus_tag="LSX49_004031"
     CDS             70..1359
                     /gene="uraA"
                     /locus_tag="LSX49_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBL7170370.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKLISMLRPEEVVLDAEDADITDK"
     gene            1409..2155
                     /gene="hda"
                     /locus_tag="LSX49_004032"
     CDS             1409..2155
                     /gene="hda"
                     /locus_tag="LSX49_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HBL7170371.1"
                     /translation="MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSS
                     LLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVP
                     EVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
                     GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRT
                     LFMTLDQLDRASITAQRKLTIPFVKEILKL"
     gene            complement(2293..2652)
                     /gene="arsC"
                     /locus_tag="LSX49_004033"
     CDS             complement(2293..2652)
                     /gene="arsC"
                     /locus_tag="LSX49_004033"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311384.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HBL7170372.1"
                     /translation="MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAAT
                     LRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSEEALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPEQVLEIVG"
     gene            complement(2673..4136)
                     /gene="bepA"
                     /locus_tag="LSX49_004034"
     CDS             complement(2673..4136)
                     /gene="bepA"
                     /locus_tag="LSX49_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HBL7170373.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANDAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            4349..5410
                     /locus_tag="LSX49_004035"
     CDS             4349..5410
                     /locus_tag="LSX49_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL7170374.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQD"
     gene            complement(5508..5978)
                     /gene="bcp"
                     /locus_tag="LSX49_004036"
     CDS             complement(5508..5978)
                     /gene="bcp"
                     /locus_tag="LSX49_004036"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBL7170375.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            complement(5978..6550)
                     /locus_tag="LSX49_004037"
     CDS             complement(5978..6550)
                     /locus_tag="LSX49_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HBL7170376.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            6696..7574
                     /gene="dapA"
                     /locus_tag="LSX49_004038"
     CDS             6696..7574
                     /gene="dapA"
                     /locus_tag="LSX49_004038"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBL7170377.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            7591..8625
                     /gene="bamC"
                     /locus_tag="LSX49_004039"
     CDS             7591..8625
                     /gene="bamC"
                     /locus_tag="LSX49_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HBL7170378.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSEWHELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            8838..9551
                     /gene="purC"
                     /locus_tag="LSX49_004040"
     CDS             8838..9551
                     /gene="purC"
                     /locus_tag="LSX49_004040"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBL7170379.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            9719..10582
                     /locus_tag="LSX49_004041"
     CDS             9719..10582
                     /locus_tag="LSX49_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HBL7170380.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            10597..12612
                     /gene="tmcA"
                     /locus_tag="LSX49_004042"
     CDS             10597..12612
                     /gene="tmcA"
                     /locus_tag="LSX49_004042"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HBL7170381.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEERWCFDHALKLRDALP
                     GDWLWISPQPDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWDEWENQPDADSLRWSDCPDPIATPHFVQHFKRVLTANNDAILWRQNQPFSL
                     AHFTPRTDWHPATGAPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAG
                     SAIVTAPAKAATDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLYQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHTPQGNIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGGNEIAGALWLVDEGGLSQELSQAVWAGFRRPRGNLVAQSLAAHGSNPLA
                     ATLRGRRVSRIAVHPTRQREGTGRQLIAGALQYIHDLDYLSVSFGYTEELWRFWQRCG
                     FVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQWNGEMLPVD
                     PLNDAVLSDDDWLELAGFAFTHRPLLTSLGCLLRLLQTSELALPALRGRLQKNASDAQ
                     LCTTLKLSGRKLLLVRQREEAAQALFALDDVRTERLRDRITQWQFFH"
     gene            12686..13384
                     /gene="ypfH"
                     /locus_tag="LSX49_004043"
     CDS             12686..13384
                     /gene="ypfH"
                     /locus_tag="LSX49_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL7170382.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARVNAIMPTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMALESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(13465..13665)
                     /locus_tag="LSX49_004044"
     CDS             complement(13465..13665)
                     /locus_tag="LSX49_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HBL7170383.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(13693..14820)
                     /gene="dapE"
                     /locus_tag="LSX49_004045"
     CDS             complement(13693..14820)
                     /gene="dapE"
                     /locus_tag="LSX49_004045"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HBL7170384.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFINELVAIE
                     WDQGNDFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(14824..15180)
                     /locus_tag="LSX49_004046"
     CDS             complement(14824..15180)
                     /locus_tag="LSX49_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HBL7170385.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNG
                     FINELGWEALLNTRGTTWRKLDETTRNKITDAASAATLMTEMPAIIKRPLLCAPGKPM
                     LLGFSESSYQQFFHEV"
BASE COUNT         3418 a         3813 c         4171 g         3858 t
ORIGIN      
        1 aagccgactt taagagtcgg cttttttttg agtaaagcgc ctataacaca taatacagag
       61 gataatacta tgacgcgccg tgctatcggg gtgagtgaaa gaccgccact tttacagaca
      121 atcccgctta gtttgcaaca tttgttcgcc atgtttggtg caaccgtcct ggtgcccgtc
      181 ttatttcata ttaacccggc gactgtactg ttatttaacg gtataggaac actgctgtat
      241 ctcttcatct gtaaagggaa aattccggct tatcttggtt ccagctttgc ctttatttca
      301 ccggtattgt tactgttgcc gttggggtat gaagtcgcgc tgggcggctt tattatgtgc
      361 ggcgtgctgt tctgcctggt ttcttttatc gtgaagaaag cggggaccgg ctggctggac
      421 gtgctgtttc cacctgcggc aatgggcgca atcgttgccg tcatcggtct ggagctggcg
      481 ggcgtagctg ccggtatggc gggtttactc ccggctgaag ggcaaacgcc agactccaaa
      541 accatcatca tctctattac caccctggcg gtcacggttt taggttccgt gctgtttcgt
      601 ggtttcctgg caattatccc gattttaatt ggcgtgctgg tggggtacgc gctctctttc
      661 gcaatgggaa ttgtcgatac cacgccgatt attaatgctc actggtttgc gctgccgacc
      721 ctctatacgc cgcgcttcga gtggtttgcc attctgacta ttctgccagc ggcgttagtg
      781 gttattgccg aacacgtagg gcacctggta gtaacggcta atatcgtcaa aaaagatctg
      841 ctgcgcgatc caggtctgca ccgttcgatg tttgctaacg gcttgtcgac cgtgatctcc
      901 ggcttctttg gctccacgcc aaacaccact tacggagaaa acattggcgt gatggcgatc
      961 acccgtgttt acagtacctg ggttatcggc ggtgcggcga ttttcgctat cctgctttcc
     1021 tgcgtcggta aactggctgc tgctatccag atgattccat tgccggtgat gggcggcgtt
     1081 tcgctgctgc tttacggtgt catcggtgct tccggtattc gtgtgttgat cgaatcgaaa
     1141 gtggattaca acaaagcaca gaacctgatc ctgacttccg tgattttgat catcggcgtc
     1201 agtggcgcga aggtaaacat tggggcggcg gagctgaaag gtatggcgct ggcgaccatc
     1261 gtcggtatcg gcttaagttt gatcttcaaa ctgattagta tgctgcgccc tgaagaagtg
     1321 gtgctggacg cagaagacgc ggatataaca gacaaataat gtaccgaccg ggcagtgttg
     1381 ctgcccggtt caaacatcat gggattctgt ggtaaacttc tcgcgatttt gtgaaatcct
     1441 ggttgaggta tctctgaaca caccggcaca gctctctttg ccactttatc ttcctgacga
     1501 cgaaaccttt gcaagtttct ggccggggga taactcctct ttactggccg cgctgcaaaa
     1561 cgtgctgcgt caggaacata gcggttacat ctatctctgg gcacgcgaag gcgcggggcg
     1621 cagccatctg ctgcacgcgg cttgcgcgga attgtcgcag cgtggcgatg cggtgggcta
     1681 tgtcccgctg gataaacgca cctggtttgt tccggaagtg ctcgacggta tggagcattt
     1741 gtcgctggtc tgtattgaca acattgagtg tattgccggc gatgagttgt gggagatggc
     1801 gattttcgat ctctacaatc gaattctgga atcgggcaaa acacggttgt tgatcaccgg
     1861 cgatcgtcca ccgcggcagt tgaatctggg attaccggat ctcgcgtcgc gtctcgactg
     1921 ggggcagatc tacaaattgc agccactttc tgatgaagat aagttgcagg cgctacagtt
     1981 acgcgcgcgt ttgcgtggtt ttgaactgcc ggaagatgtg gggcgtttct tgctgaagcg
     2041 gctcgacaga gaaatgcgca cgttgtttat gacgctggat cagctggatc gtgcgtcgat
     2101 taccgcgcaa cgcaagctga ccattccttt tgtgaaagaa attctgaagt tgtagataag
     2161 gtgtttattg tcggatgcgg cgcgaacgcc ttatccgacc tacgcgaagt taatccatag
     2221 tattcgtagg ccggataaga cgcggcaagc gtcgcatccg gcaatgtgct tcaactagcg
     2281 atggagcaca tcttaaccca cgatttccag tacctgctcc ggtggacgac caatccgtgc
     2341 tttgccattc gcgaccacaa tcgggcgttc cattagtttc ggattatcca ccatcgcctg
     2401 aatcagcgcc tcttcgctaa gtgaactgtc agccaggttc agttctttat aaagatcctc
     2461 tttttggcgc atcaattcac gagcgctatt catccccagc attttcagca aatcacgcag
     2521 cgttgccgca tcggcgggtg tctcaaggta gagcaccact tctggctcca cgccgttttc
     2581 tttcagcagg ttcagcgttt cccggctctt tgaacagcgt gggttatggt agatttttac
     2641 ctgtttggtc attgttcttc ctttaatgcg aattacatct tggtataagg cttaaagcgt
     2701 tcctgcagct ggcgcaactg gtcgatgcgc gcatcgtaac gcgcttgttg caggctgcct
     2761 aatttcacct gcgaactggc gctactcaac aaggaaatag cctgatcgag tcgcccggcg
     2821 agcgcataac cttctgctcg cgcagccagt tcctgatcgc ggttatttag tgcggcttcc
     2881 gcctgtgcca gtaaatccca gccgttgctg tcatctttat tgttaaaagt gtagcgattc
     2941 agaatattgg ccgcttcctg tggttgcccc ccttgcagat aagcgttcgc caggttgagc
     3001 tgcaacaccg gattggtgcg caaatcgcgg gcatttttca ggcgattgat agcgtcattg
     3061 gctttgtttt gcccaagatc gatatcggta gccagatcga gataccatgc gttgccaggt
     3121 tctgctgcca gtaacggttg cagcgtttta cgcgcttcgt cgtatttatt ggcttccatc
     3181 gcctgtagag cacgaccata ttgcgccgct cgttgctgac gaacgtttcc tttcgcccat
     3241 tcatccagca aatcactggt gagctggtta cgtccggaat tatacatccc cagtgtgcgc
     3301 gctttcgcca gatagaaatc ttccgacgac tgcaccacca tcgggcgcat ctgattagca
     3361 cggttgcggg catctgccag acgactttcc ggcaacgggt gagtcaataa aatttccggc
     3421 ggacgcgagg agtaacgcgc ctgatcgagt aatttttcga ggaaggtcgg catcgcctgc
     3481 ggatcgaatc ccgagcgttg cagcacctga ataccaatgc ggtccgcttc ctgttcattt
     3541 tgctgggtga aactgatcat cccctggcgc gttcccgcca gtgtaccggt cagcgccgcc
     3601 atccccgcct gcggactggc catcgccagt aaaatagaac ctaacgcgcc gacccaggtc
     3661 agcggcgcgc tgcgctgctg atcttccatc gctcgcgcca ggtgacgttg ggtgacgtgg
     3721 gagatttcgt gcgccataac tgaagccagt tgactttcgt tatcggaata acggaacagg
     3781 gcagagtgca gcaccacgtt gccgccaaag aaagcaaagg cgttaatttc gtcgttgttg
     3841 atcagaaaga aatgaaacgg tgtcttaacc gaattggcat gcgaaaccag acgcattcct
     3901 agcgaattaa tatattgcgt taatagcggg tcattaatta acggcgcgct gccgcgtaac
     3961 tggcggacat aatagtcgcc catctgcatt tcctgaccaa tggaaagtgt gcttcctgcg
     4021 gaggttccca tatccggcaa ggtgtctgcg ctgtcggcaa acgccggggc tacctgacca
     4081 atggtcatag cagcaatgag ggttgcaacc aggttttttt tcaactgcct gaacataacc
     4141 tctatcctgt atttctggag atagtcattt gaccgatact gtgaaatatc gttcccaccg
     4201 cgccgccttt gagtgtaacg acgaagatta gcccactcaa ataacttttc agtttcctga
     4261 atccgtcata aaaagcgaag tcttttttgt gacatttcga tacaattgcg gatcgcaatc
     4321 ccgctcttga ggttcaggta aggtctgtat gctcgaaatg ttgatgcaat ggtatcgccg
     4381 ccgttttagc gacccggaag cgattgcctt gctggttatt ttagtcgccg gatttggcat
     4441 tatctttttc tttagtggcc tgcttgctcc gttgctggtg gctattgtgc tggcctattt
     4501 gctggagtgg ccaaccgtgc gcctgcaatc tattggctgt tcccgccgct gggcgacgtc
     4561 gattgtattg gtggttttcg tcggtatatt gctactgatg gcgttcgtgg ttctgcctat
     4621 tgcctggcag cagggcatct acttaatccg cgatatgccg gggatgctca ataagctttc
     4681 tgactttgcc gccacgttgc cgcgccgcta tccggcgtta atggatgcgg gcattattga
     4741 tgcaatggcc gaaaatatgc gcagtcggat gctgaccatg ggcgattcgg tggtgaaaat
     4801 ttccctcgcc tcgttggtcg gtttgctgac cattgccgtc tatctggtgc tggtgccatt
     4861 gatggtcttc ttcctgctga aagacaaaga gcagatgctg aacgccgttc gccgggtgct
     4921 gccgcgcaac cgtggactgg caggacaggt gtggaaggag atgaatcaac aaatcaccaa
     4981 ctatatccgc ggcaaagtgc tggagatgat cgtggtaggg atcgccacct ggctggggtt
     5041 cttgctcttt gggctgaact attcgctgct gctggcggtg ctggtcggct tctcggtact
     5101 tattccgtac attggcgcat ttgtggtgac cattccggtg gttggcgtgg cgctattcca
     5161 gtttggtgct ggcacggaat tctggagctg cttcgcggtg tatctgatta ttcaggcgct
     5221 ggacggcaac ctgttagtac cggtgttgtt ctccgaagcg gttaacctgc atcctctggt
     5281 gattatttta tcggtggtga tcttcggtgg tttgtgggga ttctggggcg tattcttcgc
     5341 tattccattg gcgacgctga tcaaagccgt gattcacgcc tggcctgatg ggcaaatcgc
     5401 gcaagactga ccttcagcga aaaatttgaa acgagtgttg cagggcagtg agaagatttg
     5461 agatgtgctg gccgcaagcg cagccagcac ggaatggagc aaagtaatca ggcgtgttct
     5521 ttcagccagt tcagcacaac gtcgtggtga ttgctggttt tgaaatcgtc aaagacatgt
     5581 tcgattttgc catcagcgtc aatcaggaag ctgatgcgat gaataccatc gtaggttttg
     5641 cccatgaagg acttttcacc ccagacgccg aattgttcgc acacctggtg gtcctcatca
     5701 gacaggagcg taaagttaag cagctctttt tccgcaaaac gggagagttt ttcgggttta
     5761 tcggtgctga tacccagcac atcaacgccc gcttttttca actcatccat gttatcgcgt
     5821 aagccgcagg cctgtacggt acagccgggg gtcatggctt tcgggtagaa ataaaccaga
     5881 acacgctgtc cctggaagtc ggtcaaatta acttgttctc cgtcttgatc cggcaagcta
     5941 aatttcggtg cgatatcacc ggctttcagt ggattcatta cttaactcca tcctgttcat
     6001 catgttggga ataattgacg acgttaatac tgccttgtgc attgagttct gtacataggg
     6061 ctttgaacgc ttgctcaata tttgctgcgt ccgcagatgc ggggctgtgg gcagttatct
     6121 gaatatgtaa ctgcgcagcc cgttcatttt cagcaggttg cgtgcgcgac accagctccg
     6181 caatgttcat atgatgcgcg tcgaaaagtg ctgtgaagcg ttcaattaaa tgcggggagt
     6241 ctgccacatc gacctgaacc cagacagatg ctggcattgg tggacgcgga cgcgccgtcg
     6301 tgcgcttcat cacgattaaa agatccagtt cggcaccttt caacggtaac gttgattcaa
     6361 tcagggtgat tgcattccat gaaccggaaa gcagcatgat aaacgtgaac tcttctccca
     6421 gcatcgccag gcgactgtct tcaatattac agccgcaact actgacatga cgggtgatgg
     6481 tgttcactat tccagggcga tcggcaccca acgcagtgat caccagataa tgttgcgatg
     6541 acagtgtcaa actggttatt ccttcaaggg gtgagttgtt cttaaggaaa gcataaaaaa
     6601 aacatgcata caacaatcag aacggttctg tctgcttgct tttaatgcca taccaaacgt
     6661 accattgaga cacttgtttg cacagaggat ggcccatgtt cacgggaagt attgtcgcga
     6721 ttgttactcc gatggatgaa aaaggtaatg tctgtcgggc tagcttgaaa aaactgattg
     6781 attatcatgt cgccagcggt acttcggcga tcgtttctgt tggcaccact ggcgagtccg
     6841 ctaccttaaa tcatgacgaa catgctgatg tggtgatgat gacgctggag ctggctgacg
     6901 ggcgcattcc ggtgattgcc gggaccggtg ctaacgctac tgcggaagcc attagcctga
     6961 cgcagcgctt caatgacagc ggtatcgtcg gctgcctgac ggtaacccct tactacaatc
     7021 gtccgtcgca agaaggtttg tatcagcatt tcaaagccat cgctgaacat actgacctgc
     7081 cgcaaattct gtataatgtg ccgtcccgta ctggctgcga tctgctcccg gaaacggtgg
     7141 gccgtctggc gaaagtaaaa aatattatcg gaatcaaaga ggcaacaggg aacttaacgc
     7201 gtgtaaacca gatcaaagag ctggtttcag atgattttgt tctgctgagc ggcgatgatg
     7261 cgagcgcgct ggacttcatg caattaggcg gtcatggggt tatttccgtt acggctaacg
     7321 tcgcagcgcg tgatatggcc cagatgtgca aactggcagc agaagggcat tttgccgagg
     7381 cacgcgttat taatcagcgt ctgatgccat tacacaacaa actatttgtc gaacccaatc
     7441 caatcccggt gaaatgggca tgtaaggaac tgggtcttgt ggcgaccgat acgctgcgcc
     7501 tgccaatgac accaatcacc gacagtggtc gtgagacggt cagagcggcg cttaagcatg
     7561 ccggtttgct gtaaagttta gggagatttg atggcttact ctgttcaaaa gtcgcgcctg
     7621 gcaaaggttg cgggtgtttc gcttgtttta ttactcgctg cctgtagttc tgactcacgc
     7681 tataagcgtc aggtcagtgg tgatgaagcc tacctggaag cggcaccgct tgcggagctt
     7741 catgccccgg ctggaatgat tttgccggtg acctccggcg attatgcaat cccggtgacc
     7801 aacggtagtg gtgctgtcgg taaggcgctg gacattcgtc caccagccca gccgttggca
     7861 ctggtttctg gcgcgcgtac ccagttcacg ggcgataccg cttcattgct ggtggaaaat
     7921 ggtcgtggca atactctgtg gccgcaggtg gttagcgtgc tgcaggcgaa aaactacacc
     7981 atcacccaac gtgatgatgc tggtcagaca ctgaccaccg attgggtaca atggaaccgt
     8041 ctggacgaag acgagcagta tcgtggtcgt tatcaaatct ctgttaagcc gcagggttat
     8101 cagcaggcgg ttacggttaa actgctgaac ctggaacagg cgggcaaacc ggttgcagac
     8161 gcggcgtcca tgcagcgtta cagcacggag atgatgaacg ttatttccgc cggtctggat
     8221 aaatctgcca ctgacgccgc gaacgctgcg caaaatcgtg cctccaccac tatggacgta
     8281 caaagtgcag ctgatgacac cggtttacca atgctggtcg tacgcgggcc gttcaatgtg
     8341 gtttggcaac gtctgccagc tgcgctggaa aaagtgggca tgaaagtgac cgacagcacc
     8401 cgttcgcagg gcaacatggc cgtaacttat aagccgctgt ctgacagcga atggcacgaa
     8461 ctgggcgcga gcgatccagg tctggcatcc ggtgactata aactgcaggt tggcgattta
     8521 gataaccgca gcagcctaca gttcatcgat ccgaaaggtc atactctgac tcagagtcag
     8581 aacgacgcgc tggtagctgt cttccaggct gcgtttagca agtaaaaata cagggctgga
     8641 gtcatccggc ccttttttct gatatgatac gcaaacgtgt gcgtcggcag aaaaacgcga
     8701 ttttagcggt aattcgcacg aaatttgttt gtcggacgta ggtcggataa ggcgttcacg
     8761 ccgcatccga caaaacatcc ggcacaccag acagcaaaag attttaaaac gttaattcac
     8821 acccaggagt gataaagatg caaaagcaag ctgagttgta tcgtggtaaa gcgaaaaccg
     8881 tatacagcac ggaaaacccg gacctgttgg tgctcgaatt ccgcaatgat acgtcagcag
     8941 gggatggcgc gcgcattgag cagtttgatc gcaaaggtat ggtgaacaac aagttcaact
     9001 acttcattat gagcaaactg gctgaagcgg gtatcccgac tcaaatggag cgtctgctct
     9061 ccgataccga atgtctggtg aaaaagctgg atatggtgcc ggttgagtgt gtcgtgcgta
     9121 accgtgctgc tggctctctg gtgaaacgtc ttggaatcga agaaggtatt gagctgaacc
     9181 cgccgctgtt cgatctgttc ctgaaaaacg acgccatgca cgatccgatg gtcaacgaat
     9241 cttactgcga aacctttggc tgggtgagca aagagaacct ggcgcgtatg aaagagctga
     9301 cctacaaagc gaacgacgtg ctgaaaaaac tgttcgatga tgctggtctg attctggtcg
     9361 acttcaagct ggagtttggt ctgtacaaag gcgaagtggt tctgggcgat gagttctccc
     9421 cggacggcag ccgcctgtgg gacaaagaaa cgctggagaa aatggacaaa gaccgtttcc
     9481 gccagagcct cggtggcctg atcgaagcct atgaagccgt cgcccgccgc ctgggtgtac
     9541 agctggactg atttttctgt tcatcatctt gccgtgctgc tggcacggca agacaaccgc
     9601 tctcataaga tgagtattga acgctcattc ctccgccatt tcatcccgct ttcctgtggt
     9661 aatcttcctc tgaaccacct acgatcattt ctataatgaa tataatgttg aggtatctat
     9721 gcgttggcaa gggcgacgtg aaagtgacaa tgttgaagac aggcgcaata gctccggcgg
     9781 tccgtcaatg ggcggtcccg gttttcgcct gccaagcggt aaaggcgggc tgattttact
     9841 gatagtcgtg ctggttgcag gctactatgg cgttgattta accgggttga tgaccggaca
     9901 gccggtttcc caacagcaat caacgcggtc aattagccct aatgaagacg aagccgcaaa
     9961 attcacctcg gtgattctgg caaccacgga agacacctgg ggacagcaat tcgagaagat
    10021 gggtaaaacc tatcagcaac cgaagctggt catgtaccgt ggaatgacgc gtaccggctg
    10081 cggggcgggc cagtccataa tggggccatt ctattgcccg gcggatggca cagtttatat
    10141 cgatctctcc ttctatgatg acatgaaaga caaacttggc gcggatggcg attttgccca
    10201 ggggtacgtt atcgctcatg aagtcggtca tcatgtgcag aaactgttag gcatcgagcc
    10261 gaaagttcgt caactgcaac aaaacgcgac gcaggcggaa gtaaaccgct tatctgtgcg
    10321 tatggaactc caggccgact gttttgccgg tgtctggggg catagtatgc agcagcaagg
    10381 tgttctggaa accggcgatc tggaagaggc gctgaacgcg gcgcaggcca tcggcgatga
    10441 ccgtttacaa cagcaaagtc aggggcgagt agtaccagac agtttcactc atggcacttc
    10501 tcagcaacgc tacagctggt ttaaacgtgg tttcgacagc ggcgatccgg cacaatgcaa
    10561 tacttttggt aaaagcattt aacttccggg gcagggatgg ctgaactgac tgcgcttcac
    10621 acattaacag cgcaaatgaa acgtgaaggg atccgccgct tgctggtgtt gagcggggaa
    10681 gagcgttggt gttttgatca tgcgcttaag ttgcgtgatg ccttacctgg cgactggctg
    10741 tggatttcgc cgcagccaga tgctgaaaac cactgttctc cctcggcact acaaacttta
    10801 cttgggcgcg agttccggca tgcggtattc gacgcccgcc acggctttga tgccgctgcc
    10861 tttgcggcac ttagcggaac gttgaaagcg ggaagctggc tggtgttgtt actccctgta
    10921 tgggatgagt gggaaaacca acctgatgcc gactcgctgc gctggagtga ttgccctgac
    10981 cctattgcga cgccgcattt tgtccagcat ttcaaacgcg tacttacggc gaataacgac
    11041 gctatcctct ggcggcaaaa ccagccgttc tcgttggcgc attttactcc ccgtactgac
    11101 tggcaccccg ctaccggcgc accacaacca gaacaacagc aactcttaca gcagctactg
    11161 accatgccgc cgggtgtggc agcggtaact gctgcgcgtg ggcgcggtaa gtcggcgttg
    11221 gcagggcaac tcatttctcg tattgcgggc agtgcgattg tcaccgctcc cgcaaaagcg
    11281 gcaacggatg tactggcaca atttgcgggc gagaagtttc gctttattgc gccggatgcc
    11341 ttgttagcca gcgatgagca agccgactgg ctggtggtcg atgaagccgc agctatacct
    11401 gcgccgttgt tgtatcaact ggtatcgcgt tttcctcgaa cgttgttaac tactacggtg
    11461 cagggctacg aaggcaccgg acgtggtttt ttgctgaaat tttgcgctcg ctttccgcat
    11521 ttacaccgtt ttgaactaca acagccgatc cgttgggcgc agggatgccc gctggaaaaa
    11581 atggttagtg aggcactggt gtttgacgat gaaaacttca cccatacacc acaaggcaat
    11641 atcgttattt ccgcatttga acagacgtta tggcgaagcg agccagaaac gccgttaaag
    11701 gtttatcagt tattgtctgg tgcgcactac cggacctcgc cgctggattt acgccgcatg
    11761 atggatgcac caggtcaaca ttttttacag gcggctggcg gaaacgagat tgccggagcg
    11821 ctgtggctgg tggatgaggg cggattatct caagaactca gtcaggcggt atgggcgggt
    11881 tttcgtcgcc cgcggggtaa tctggtggcc cagtcgctgg cggcgcacgg cagcaatcca
    11941 ctggcggcga cattgcgcgg acggcgggtt agccggatag cagttcatcc gactcgtcag
    12001 cgggaaggca cagggcgaca gcttattgct ggtgctttgc aatatattca tgacctcgac
    12061 tatctttcgg tgagttttgg ttacaccgag gagttatggc gtttctggca acgctgcggt
    12121 tttgtgctgg tgcgaatggg taatcatcgt gaagccagca gcggttgcta tacggcgatg
    12181 gcgctgttac cgatgagtga tgcgggtaaa cagctggctg aacgtgagca ttaccgttta
    12241 cgtcgcgatg cgcaagctct cgcgcagtgg aatggcgaaa tgcttcctgt tgatccacta
    12301 aacgatgccg tcctttctga cgacgactgg cttgaactgg ccggttttgc tttcactcat
    12361 cgtccgctat taacgtcgtt aggttgctta ttgcgtctgc tacaaaccag cgaactggca
    12421 ttaccggcgc tgcgtgggcg tttacagaaa aacgccagtg acgcgcagtt atgtaccaca
    12481 cttaaacttt caggccgtaa gctgttactg gttcgccagc gggaagaggc cgcgcaggcg
    12541 ctattcgcac ttgatgatgt tcgcactgag cgtctgcgcg atcgcataac gcaatggcaa
    12601 ttttttcact gactccttca attttctccc atggtcattg tgagtcagcg gcgtaaaatt
    12661 aatgacatca gttaaggagt tcgccatgaa acatgaccat tttgttgttc aaagcccgga
    12721 taaaccagca caacagttgt tactgctttt ccacggtgtc ggggataacc cggtggcaat
    12781 gggggaaata ggtagctggt ttgcgccgct gtttcctgat gcgctggtgg tgagtgtcgg
    12841 tggcgcggag ccgagcggta atccggcggg gcgtcagtgg ttttcggtgc agggtattac
    12901 ggaagataat cgccaggcgc gtgtgaatgc catcatgccg acgtttattg agacggtgcg
    12961 ctactggcag aaacaaagcg gagtaggggc taacgccacg gcgctaatcg gtttctcaca
    13021 aggcgcgatt atggcgctgg agagcattaa agccgaaccg ggccttgctt cgcgcgtcat
    13081 tgccttcaac ggacgctacg cgagcctgcc ggaaaccgcg tctacagcca caacaattca
    13141 cttgattcat ggcggtgaag atccggttat cgatctggcg catgcggttg cggcgcagga
    13201 agcgttaatc agtgccggtg gtgacgtgac gctggatatc gtggaggatt taggccatgc
    13261 gatcgacaat cgcagtatgc aatttgccct ggatcacttg cgttatacca ttccgaaaca
    13321 ttatttcgac gaagcgctaa gcggcggtaa gcctggcgat gatgatgtga ttgaaatgat
    13381 gtaataatag ccgggtaggt ctgataagac tgtatcaggc atcatggccg gatgcggcgt
    13441 taacgcctta tccggccact tagcttactt cttcggttga tcctttttcg gccagtcgtc
    13501 gtcatcgtcc cacttatcgt tgaaatcacg atgcggggga agctccggct tgttggcgag
    13561 aaatttctta tggtcgacgc gcttgagatc tttaatcacg ttcagcagga cgcctaccaa
    13621 aaagacaatc accagaatcc accaatattt agccagccag tccatgctta tttcctcttg
    13681 cagaaccact catcaggcga cgagctgttc catgatacgt tgatacatac gggcaagtag
    13741 ctgcaggtcg gcagcgttca cacattcatt gattttatga atcgtggcat tgaccggccc
    13801 gagttccacc acctgcgccc ccatgcgggc aataaagcgc ccgtcggacg ttccgcctgt
    13861 ggtcagtagc tgcggtttaa tttcattata gtgctcaacc gcgttaacga ccgcatccac
    13921 cagtttaccg cgcgcggtca aaaatggctg cccggaaagc caccaatcca ccgtatagcg
    13981 cagttgatgt ttttcaagca gggcaagcac ctgcgctttg atcatctcat ccgtcagttc
    14041 ggtgctaaag cggaagttaa actgcacaaa cagttcacct ggaataacgt tgttactgcc
    14101 cgttcccgcc tgaatattgg caatctgcat actggtcgcc gggaagaagt cattaccctg
    14161 atcccactca atagccacta attcattaat gaaaggtgct gcgcgatgta ccggattgtc
    14221 agccagatgt gggtaggcaa catgcccctg aacgccatga atggtaaggt tgcaggttaa
    14281 cgatccgcga cgaccatttt tcaccacatc acctaccact tcgatactcg acggttcgcc
    14341 aaccagacag taatcgagac gctcattacg cgccattaac gcttcgacga cttttaccgt
    14401 accgttgtgg gcactagctt cttcatcaga ggtgatcaga aatgccagtc gccctgtatg
    14461 gttgggatgt tgtgcgacaa agcgttctgc cgctaccacc atcgccgcca gcgagccttt
    14521 catatctgcc gcacctcgcc caaataacat gccgtcacga atggttggtt caaatggtgg
    14581 attgatccaa cggtcggcgt cgccaggcgg caccacgtcg gtatgcccgg caaaggctaa
    14641 cgtttcaccc tgcccgcgcc atgcccaaaa attctgcgta tcggcaaagt ccatgcgttc
    14701 aacggtaaaa ccgatcgcct gcaaacgttc aatcaacaaa gcctggcatc ctgcgtcatc
    14761 aggactcagg gaagggcggc gaataagctg ttgtgtcagc tcaataaccg ggcacgacat
    14821 agactacacc tcatggaaaa attgctgata actggattca ctgaaaccca gcagcatagg
    14881 cttaccaggc gcgcagagca atggacgttt gataattgca ggcatttcag tcattaatgt
    14941 cgccgcagag gccgcatcgg tgattttatt gcgggtggtt tcgtccagtt tacgccaggt
    15001 tgtaccacgg gtgttgagta acgcttccca gcctaattcg ttgataaaac cgttcaataa
    15061 ttcgctgtcc aatccatcga cgcggtaatc atgaaaacga tagtcgatgt tattggcttc
    15121 cagccaacgg cgagcctttt taatggtgtc acaatttttg atgccgtaaa gtgtaaccat
    15181 aatgaatcct ttttcgattt atgagaataa atactcattt aagggtgaaa acattttgcc
    15241 tgcaaatgat tatcaggaaa
//
LOCUS       DAFGPF010000114        15246 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFGPF010000114 DAFGPF010000000
VERSION     DAFGPF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15246
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.114"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1197
                     /gene="dsdX"
                     /locus_tag="LSX49_004047"
     CDS             <1..1197
                     /gene="dsdX"
                     /locus_tag="LSX49_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
                     /protein_id="HBL7170386.1"
                     /translation="PLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGL
                     TLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCT
                     ALMAVHCVVPPHPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPF
                     KPVPTEFADLKVRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGFYTLLEFI
                     GNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILK
                     SSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDI
                     SPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTF
                     LLSFII"
     gene            1215..2543
                     /gene="dsdA"
                     /locus_tag="LSX49_004048"
     CDS             1215..2543
                     /gene="dsdA"
                     /locus_tag="LSX49_004048"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HBL7170387.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGH"
     gene            3654..4220
                     /locus_tag="LSX49_004049"
     CDS             3654..4220
                     /locus_tag="LSX49_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HBL7170388.1"
                     /translation="MPKSYTPNWFFTALLDNHINQMMARYSCLRALRMDFFYRKDTPD
                     FLQPDHRWLELQLRMLLEQVEQFENIVGFFWVIEWTADHGFHAHVVFWIDRQRVKKIY
                     PFAERIAECWQAITYNCGSAHRCTYQPHYAYNINIPVRHNDPESIDNIRGALHYLAKE
                     EQKDGLCAYGCNEVPERPAAGRPRKPHF"
     gene            4467..5027
                     /locus_tag="LSX49_004050"
     CDS             4467..5027
                     /locus_tag="LSX49_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170389.1"
                     /translation="MNAIPYFDYSLAPFWPSYQNKVIGVLERALREQSGSRIRRILLR
                     LPWEHDNAFNSRQTWFGMDFIETVSALMNAKPGRDLCWLLTRHPEKPEYHVVLCVRQE
                     YFDGPELDRLILDAWSNVLGFASPGEAKPYQKQITRDVVLDRRSPDCEALFKDLIWAF
                     SDFARDRRGVCDPEARCLAGNPGWQC"
     gene            5096..5329
                     /locus_tag="LSX49_004051"
     CDS             5096..5329
                     /locus_tag="LSX49_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBL7170390.1"
                     /translation="MLTTTSHDSVWLRADDPLIDMNYITSFTGMTDKWFYRLISEGHF
                     PKPIKLGRSSRWYKSEVEQWMQQRIEESRGAAA"
     gene            5595..6143
                     /locus_tag="LSX49_004052"
     CDS             5595..6143
                     /locus_tag="LSX49_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170391.1"
                     /translation="MQITEALISEPGDIRRFIQHAVDHWPRLLAVHFILHSTEGNIYG
                     QQIHAFCTSFYRQLHERITESNHTASPSSSVVLRWLREQHGGATIRCLLLLSQTSICH
                     PRASVTVDEQCSQVVDLLQHSWQVISAGGQCRVERCFRVARGDTSGQYVALKTVALSL
                     GLPVVTAITHRPVQRCTLITAQ"
     gene            6411..7034
                     /locus_tag="LSX49_004053"
     CDS             6411..7034
                     /locus_tag="LSX49_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL7170392.1"
                     /translation="MRTRIDYLADKYSFTERNESPRLRRQWQDVLEECRLTEAGPEER
                     LRIALLNVDYVTSFELPFRLLLTRTPQLIAALREEWGLSQKNVVFNDKRFGCVYSLKA
                     SLSGVPDTFRYHLSHRIRRMVGNENTSSPYQQIAREVKVPRERLKYALEAGLLVTALD
                     GLFWSGSQRIAADILRLRKSGMPVVTTSVEASDNLTGTTRKIPAYHL"
     gene            7132..7365
                     /locus_tag="LSX49_004054"
     CDS             7132..7365
                     /locus_tag="LSX49_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170393.1"
                     /translation="MARSDYDFINLSLGHELNEWLAERGYAGQADNRNRLAEVVTRKL
                     RDSFYADVSWDALNVAYSEHPEWFSELASGDED"
     gene            7729..9495
                     /locus_tag="LSX49_004055"
     CDS             7729..9495
                     /locus_tag="LSX49_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HBL7170394.1"
                     /translation="MQHRQDNLLANRNLLPGMVSGQYAFRIRTLSQVVRYFSLLPCLC
                     ILSFSSPAAMLSPGDRSAIQQQQQQLLDENQRQRDALERSAPLTITPSPETSAGTEGP
                     CFTVSRIVVSGATRLTSAETDRLVAPWVNQCLNITGLTAVTDAVTDGYIRRGYITSRA
                     FLTEQDLSGGVLHITVMEGRLQQIRAEGADLPGRTLKMVFPGMEGKVLNLRDIEQGME
                     QINRLRTEPVQIEISPGDREGWSVVTLTALPEWPVTGSVGIDNSGQKNTGTGQLNGVL
                     SFNNPLGLADNWFVSGGRSSDFSVSHDARNFAAGVSLPYGYTLVDYTYSWSDYLSTID
                     NRGWRWRSTGDLQTHRLGLSHVLFRNGDMKTALTGGLQHRIIHNYLDDVLLQGSSRKL
                     TSFSVGLNHTHKFLGGVGTLNPVFTRGMPWFGAESDHGKRGDLPVNQFRKWSVSASFQ
                     RPVTDRVWWLTSAYAQWSPDRLHGVEQLSLGGESSVRGFKEQYISGNNGGYLRNELSW
                     SLFSLPYVGTVRAVTALDGGWLHSDRDDPYSSGTLWGAAAGLSTTSGHVSGSFTAGLP
                     LVYPDWLAPDHLTVYWRVAVAF"
     gene            9508..12672
                     /locus_tag="LSX49_004056"
     CDS             9508..12672
                     /locus_tag="LSX49_004056"
                     /inference="COORDINATES: protein motif:HMM:NF026943.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
                     /protein_id="HBL7170395.1"
                     /translation="MHQPPVRFTYRLLSYLISTIIAGQPLLPAVGAVITPQNGAGMDK
                     AANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLK
                     AGGEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPHATLTT
                     GKPVMNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTA
                     GANRITADGRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYARE
                     GDIILNSAGKLVLKNSLAGGNTTVTGTNVSLSGDNKAGGNLSVTGTTGLTLNQSRLVT
                     DKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTDDTTLKGR
                     SVAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGAVQGNGLKVTATDLTSTGSIK
                     SGSTLDISVRNATLSGDAGAKDSARVTVSGTLENRGRLVSDDVLTLSATQINNSGTLS
                     GAKELVVSADTLTTTEKSVTNSDGNLMLNSASSTLAGETSAGGTVSVKGNSLKTTTTA
                     QTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSAPSLSLSAPELTSSGVL
                     VASALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLI
                     TGDTGSDMQRGIQAATAALQGLVGGNMAGALAGASAPELANIIGHHAGIDDNTAAKAI
                     AHAILGGVTAALQGNSAAAGAIGAGTGEVIASAIAKSLYPGVDPSKLTEDQKQTVSTL
                     ATLSAGMAGGIASGDVAGAAAGAGAGKNVVENNALSLVARGCAVAAPCRTKVAEQLLE
                     IGAKAGMAGLAGAAVKDMADRMTSDELEHLITLQMMGNDEITTKYLSSLHDKYGSGAA
                     SNPNIGKDLTDAEKVELGGSGSGTGTPPPSENDPKQQNEKTVDKLNQKQESAIKKIDN
                     TIKNALKDHDIIGTLKDMDGKPVPKENGGYWDHMQEMQNTLRGLRNHADTLKNVNNPE
                     AQAAYGRATDAINKIESALKGYGI"
     gene            12669..13055
                     /gene="cdiI"
                     /locus_tag="LSX49_004057"
     CDS             12669..13055
                     /gene="cdiI"
                     /locus_tag="LSX49_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-immunity protein system imunity protein
                     CdiI"
                     /protein_id="HBL7170396.1"
                     /translation="MITLRKLIGNINMTKEPEQQSPLELWFERIIDVPLEKLTVEDLC
                     RAIRQNLCIDQLMPRVLEVLTKEPLAGEYYDGELIAALSTIKGEDLKDQKSTFTQIRQ
                     LINQLEPSDINDDLRKDILKINQIIV"
     gene            13146..13463
                     /locus_tag="LSX49_004058"
                     /pseudo
     CDS             13146..13463
                     /locus_tag="LSX49_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13636..14100
                     /locus_tag="LSX49_004059"
                     /pseudo
     CDS             13636..14100
                     /locus_tag="LSX49_004059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpA"
     gene            14462..14977
                     /locus_tag="LSX49_004060"
                     /pseudo
     CDS             14462..14977
                     /locus_tag="LSX49_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012134273.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG N-terminal
                     domain-containing protein"
BASE COUNT         3699 a         3634 c         4085 g         3828 t
ORIGIN      
        1 ccactggata tggtaaatgc tattgaaagt ggaattggcg gaacgctggg gttccttgct
       61 gcggttatcg gcctgggcac gatactggga aaaatgatgg aagtatccgg ggccgcagaa
      121 agaattggtc tgacacttca acgctgtcgc tggctttcag ctgatgtcat tatggtgctg
      181 gttggcctga tttgcggcat cacgctgttt gttgaagtgg gcgtcgtgct attgattcct
      241 ctggcttttt caattgccaa aaaaaccaat acctcattgt taaagctggc cattccgctg
      301 tgtaccgcat tgatggcagt gcactgcgtg gttcccccac atccggctgc tttatatgtt
      361 gccaataagc ttggcgcaga tatcggttcg gtgatcgtct acggtttgct ggttgggctg
      421 atggcatcac tgatcggtgg cccacttttc cttaaatttc tgggtcaacg actgcccttt
      481 aaacctgtac ccacagagtt tgccgatctc aaagttcgcg atgaaaaaac actaccgtca
      541 ttaggcgcaa cgttattcac catactgcta cccattgcgc tgatgttggt taaaacgatt
      601 gccgaattga atatggcgcg tgagagtggt ttttatacct tgcttgagtt tattggcaac
      661 cctattactg ccatgtttat cgccgtgttt gtcgcctatt atgtgttggg tatacgccag
      721 catatgagca tggggacaat gctcacacat acggaaaatg gcttcggttc tattgctaat
      781 attttgctga ttatcggggc cggaggcgca ttcaacgcca ttttaaaaag cagcagtctc
      841 gctgatacgc tggcagttat tctctccaat atgcatatgc acccgattct tctggcctgg
      901 ttggtggcac ttattctgca tgctgcagtg ggctccgcta cggtggcaat gatgggggca
      961 acggcaattg ttgcacccat gctgccgctg tatcccgaca tcagcccgga aattattgcg
     1021 attgctatcg gttcaggtgc gattggctgc acgatcgtta cggactcgct tttctggctg
     1081 gtgaagcaat attgcggcgc tacgctcaat gaaacattta aatactatac gacagcgaca
     1141 tttatcgctt cagtcatcgc tctggcgggc acattcctgc tgtcatttat catctaagcg
     1201 caaagagacg tactatggaa aacgctaaaa tgaactcgct catcgcccag tatccgttgg
     1261 taaaggatct ggttgctctt aaagaaacca cctggtttaa tcctggcacg acctcattgg
     1321 ctgaaggttt accttatgtt ggcctgaccg aacaggatgt tcaggacgcc catgcgcgct
     1381 tatcccgttt tgcaccctat ctggcaaaag catttcctga aactgctgct actgggggga
     1441 ttattgaatc agaactggtt gccattccgg ctatgcaaaa acggctggaa aaggaatatc
     1501 aacaaccgat cagcgggcaa ctgctactga aaaaagatag ccatttgccc atttccggct
     1561 ccataaaagc acgcggcggg atttatgaag tcttggcaca tgcagaaaaa ctggctctgg
     1621 aagcggggtt gctgacgctt gaagatgact acagcaaact gctttctccg gagtttaaac
     1681 agttctttag ccaatacagc attgctgtgg gctcaaccgg aaatctgggg ttatcaatcg
     1741 gcattatgag cgcccgcatt ggctttaagg tgacagtgca tatgtctgct gatgcccggg
     1801 catggaaaaa agcgaaactg cgcagccatg gcgttacggt cgtggaatat gagcaagatt
     1861 atggtgttgc cgtcgaggaa ggacgtaaag cagcgcagtc tgacccgaac tgtttcttta
     1921 ttgatgacga gaattcccgc acgttgttcc ttgggtattc cgtcgctggc cagcgtctta
     1981 aagcgcaatt tgcccagcaa ggtcgtatcg tcgatgctga taaccctctg tttgtctatc
     2041 tgccgtgtgg tgttggtggt ggtcctggtg gcgtcgcatt cggacttaaa ctggcgtttg
     2101 gcgatcatgt tcactgcttt tttgccgaac caacgcactc cccttgtatg ttgttaggcg
     2161 tccatacagg attacacgat cagatttctg ttcaggatat tggtatcgac aaccttaccg
     2221 cagcggatgg ccttgcagtt ggtcgcgcat cgggctttgt cgggcgggcg atggagcgtc
     2281 tgctggatgg cttctatacc cttagcgatc aaaccatgta tgacatgctt ggctggctgg
     2341 cgcaggaaga aggtattcgt cttgaaccat cggcactggc gggtatggcc gggcctcagc
     2401 gcgtgtgcgc atcagtaagt taccaacaga tgcacggttt cagcgcagaa caactgcgta
     2461 atgccactca tctggtgtgg gcgacgggag gtggaatggt gccggaagaa gaaatggaac
     2521 aatatctggc taaggggcac taatgatttt gccacatcga ctcccttttt acgggagaat
     2581 gatgtggctt aaagatagtt catattttct gtcgctgaca aaagatgttg ttcaggtttg
     2641 aataagaaag aatttatcta atttttgtaa ggaaacagtt ctgtcaggga tatattcaga
     2701 acggagagtt gttcattttt acccattaaa catggataat tttaatttag gcttattact
     2761 ataattatat tcactctgtc tttactcaca ctcttctttg tctaatcttc attgtcacca
     2821 ttatcataat atccacttcc ttcttcatta ggcataacta ctgtaattca tacgatactc
     2881 agataagtta tcctctacca ttctactgat gatattcatc tgttatcagt cttcactgaa
     2941 acagtaattg attttaatct tatccatcat gaactgtatt tacttaacga taattgttta
     3001 tctgaagtgt tttaactatt ctgatgaaca tcaattcttt tgtcattact gattaactgg
     3061 atgtttactc tttgataagg tatccatgat tctgtaacga ttaacagagc tggataaaca
     3121 atgaaattga caggagagat acctgattat gtttgtttcg ggttgtattg tttaagatgc
     3181 agggtaaaaa tcatgccagt ggtatttttt actctggtaa tgtgtgcggt taacgttcat
     3241 gtccttaaga acagattgga tgagggcgta taagtttatt gcgttggcct tgtacacgtt
     3301 ttttcagact cactgagagc aagtttgtag tttatgatgt tattggtcgt aatatgtttc
     3361 ttaatctcct ggtagtgggt ttttatcgcg tgttttgcag tatttcgtga tgtttattga
     3421 ttctgtattt tattcgctcc tcgtttatct catctcttta gctaatacca tcagataatc
     3481 catttctttc tgcataatgc tgcgtatcgt taataacccg tcgtatccat tctgctacag
     3541 catgcctgat aaataccatc tgtaagttat taccgtttta gatctgatta tgagcgaaag
     3601 cattaattcg ctcacagagc ttaaaacatc attaactttc aggagtcatc aacatgccta
     3661 aatcttacac accaaactgg ttttttaccg ctttacttga caatcacatc aatcaaatga
     3721 tggcacgcta ttcctgcctg cgggccttac ggatggattt cttctacagg aaagatacgc
     3781 ccgatttctt acaacctgat catcgctggc ttgaattgca gttgcgtatg ctgctggagc
     3841 aggtggaaca atttgaaaat atcgttggtt tcttctgggt gattgaatgg acggctgatc
     3901 atggttttca tgcgcatgtc gttttctgga tcgatcgtca gagggttaaa aaaatatatc
     3961 cctttgcgga gcggatagcg gaatgctggc aggcaattac gtataactgt ggttcggcgc
     4021 accgctgtac atatcagccg cattatgcat acaacatcaa cattcctgtg cgccacaacg
     4081 atcctgaaag catcgataat attcgcggtg ccctgcatta tctggcgaaa gaagagcaaa
     4141 aagacgggct gtgtgcttac ggctgcaatg aagttcctga acgtcctgct gcagggcgtc
     4201 ctcgtaagcc tcacttctga agcttaaggc ctgagccttc gctcctggaa acactccgtc
     4261 ggtaaaaact taccgccttg attaatgatg tgaactgaag tcaacggaga tcattcatcc
     4321 tgaacctgca tccggtgttt tgttccttgt cttcccgttc tgctccggtt cttcacttat
     4381 tccatcaatc tcatccgcaa gccataacac gtcagctcat tcacgggcag gacgcattgt
     4441 gggctgcgca taacggaaca tatcttatga atgctattcc ttatttcgac tatagcctgg
     4501 cacccttctg gccatcttat cagaacaaag tcatcggcgt ccttgagcgt gcgctgcgtg
     4561 agcagtccgg ctcacggata cggcggatcc tgcttcgtct gccgtgggaa catgacaacg
     4621 ccttcaacag cagacagacc tggtttggta tggattttat cgaaaccgtc agtgcgctga
     4681 tgaatgcgaa acccggacgc gacctttgct ggctcctgac ccgtcatccg gaaaagccgg
     4741 aataccacgt ggtgctgtgc gtcagacagg agtatttcga cggccccgaa ctggatcggt
     4801 tgatactgga tgcctggagt aatgtgctgg gtttcgcgtc accaggtgaa gcaaagccgt
     4861 accagaagca gatcacccgg gatgtggtac tggatcgccg gtcaccggac tgcgaagccc
     4921 tgtttaagga ccttatctgg gcgttcagtg atttcgcccg cgatcgccgt ggagtgtgcg
     4981 atccggaagc ccgttgcctt gccggcaatc ccggttggca gtgctgaaag cagcacgcca
     5041 tcccattccc cgtattaccc cattcttcat aaatctcact gaggacattc tgaccatgtt
     5101 gaccacaaca agccacgaca gcgtatggct gcgtgccgac gatcccctga tcgacatgaa
     5161 ctacatcacc agtttcaccg gcatgaccga taaatggttt tacaggctga tcagtgaagg
     5221 gcattttcct aaacccatca aactggggcg cagcagccgc tggtacaaaa gtgaagtgga
     5281 gcagtggatg caacaacgaa ttgaggaatc acgaggagca gcagcatgaa acgtgttgtg
     5341 atgccagtac gttggcaatg tgcaaaatgc cagcgctggt attgtggaac ccggccctgc
     5401 ccctggtgct ggcgacattt acgttcatct tcttgcagac attctccagt cagcctgcag
     5461 gttatagcta ttcctgactg attcgtcatt ctattcttat tgattataac tggcattaca
     5521 ccggtgctgg cgtgctttcc tgcgtgtctg caccggtttg acaaaattca acagggtttg
     5581 aaaaggaaca tttcgtgcaa ataaccgaag ccttaatttc agagccggga gacatccggc
     5641 gttttattca acatgctgtt gaccactggc cgcgtctgct ggcagtccac ttcatactcc
     5701 attcgacaga aggaaacatc tacgggcaac agattcatgc attctgcact tccttttatc
     5761 gacaactgca tgaacgtatt actgagagca atcacactgc cagtccatca tcgtcggtgg
     5821 tattacgctg gttgcgggaa caacatggag gagcaacaat tcgatgcctg ttgctgctca
     5881 gccagacgag tatttgtcac ccgcgagcca gtgtcacagt tgatgaacaa tgttcgcaag
     5941 tggtggattt actgcaacat agctggcagg tgataagtgc tggcggacaa tgccgggtgg
     6001 aaaggtgttt tcgggttgcc cggggtgata catccggtca gtatgttgcg ttaaaaacag
     6061 tcgcattgtc tctggggtta ccggttgtga ccgccattac ccatcgtccg gtacagcgct
     6121 gtacattgat tacagctcag tgaatcagcg ctttctggct tttcgtcggt cattctgtca
     6181 acgccacgat gtttgaccgt tatggggatg cggacgattc cctgcacagc gttgtttcac
     6241 ggtggtggat gacgcaacac cgctgttaaa aacagtcgtt cagtcctttg tgttaccggt
     6301 tgtgacaaca atcagttggt aatggacgtg tgaaccatct gcgcttccgt tgatttttat
     6361 ggactgataa agttttgcca gctgaatctt tatacggaat gctcttcagt atgcgtacac
     6421 gaattgacta tctggcggat aaatactctt ttaccgaacg gaatgaatct ccacgccttc
     6481 gccggcagtg gcaggatgtt ctggaggagt gtcggctgac agaggccgga ccagaagaac
     6541 ggctgcgtat tgccctgctg aatgtggatt acgtcaccag ttttgaactg ccttttcgct
     6601 tgttgcttac tcgtacacca caactgattg ccgcgcttcg ggaagaatgg ggcctcagcc
     6661 agaaaaatgt ggtgttcaac gataaacggt ttggctgcgt gtacagcctg aaggccagtc
     6721 tttctggtgt accggataca ttccggtatc atctgtctca tcgtattcgc cggatggttg
     6781 ggaatgaaaa tacatcatcg ccatatcagc agattgcccg ggaagtgaaa gtgccccgtg
     6841 aacggctgaa gtatgcgctg gaagccggtt tactggtgac tgcactggac gggctgttct
     6901 ggtctggtag tcagcgcatt gcggctgata tcctgagact gagaaagagc ggaatgccgg
     6961 tggtgacaac gtccgtggaa gcgagcgata acctgacggg aacaacccgc aaaataccgg
     7021 cataccatct ctgacattgc gatgaagggc agatttcacc ttgacagggg cagagtgccg
     7081 ctttttatac tttattcccg tgtctgaaaa aaatgtgcaa aggaaacggg aatggcaagg
     7141 tccgattacg attttatcaa tctgtctctg ggacatgaac tgaatgagtg gctggcagag
     7201 agaggttatg ccggacaggc ggataaccgg aaccgactgg cagaggtggt tacccgcaaa
     7261 ttgcgggaca gtttttatgc ggacgtctcc tgggatgcgc tgaatgtggc atacagtgaa
     7321 caccctgagt ggttttcaga gcttgcctcc ggggatgagg attaacaggc aaattatgct
     7381 gctatcgggc agagtgatta cctgcaggga tttccattta taagaatacg ccgcttcggg
     7441 aaagctccgg ttctccggag agttacgatt atttttactc aaattcacaa cacctgaact
     7501 ggaacttgcg ttgtgtcccg gattgttact ccgcaggaag catccttttt accatacgga
     7561 tgtttgtttt ccatttcccc tccgaaaaat acaactccga tcacatttct gatattttcc
     7621 ccggatttta cataacagga ttgtttctgt atgtttttta tctggtgtaa atttcagcac
     7681 tgacattccg cttacgttaa tttacactgg ataccccacg aggagaatat gcagcaccgg
     7741 caggataact tactggcgaa cagaaatttg ttgcctggta tggtttccgg tcagtacgca
     7801 ttcaggatcc gtaccttatc tcaggtggta cgctattttt ccctcctccc ctgcctttgc
     7861 attctttcat tttcgtctcc ggcagccatg ctgtctccgg gtgaccgcag tgcaattcag
     7921 cagcaacagc agcagttgtt ggatgaaaac cagcgtcagc gtgatgcgct ggagcgcagt
     7981 gcgccgctga ccatcacgcc gtctccggaa acgtctgccg gtactgaagg tccctgcttt
     8041 acggtgtcac gcattgttgt cagtggggcc acccgactga cgtctgcaga aaccgacaga
     8101 ctggtggcac cgtgggtgaa tcagtgtctg aatatcacgg ggctgaccgc ggtcacggat
     8161 gccgtgacgg acggctatat acgccgggga tatatcacca gccgggcctt tctgacagag
     8221 caggaccttt cagggggcgt actgcacata acggtcatgg aaggcaggct gcagcaaatc
     8281 cgggcggaag gcgctgacct tcctggccgc accctgaaga tggtttttcc gggaatggag
     8341 ggaaaggttc tgaacctgcg ggatattgag caggggatgg agcagattaa tcgtctgcgt
     8401 acggagccgg tacagattga aatatcgccc ggtgaccgtg agggatggtc ggtggtgaca
     8461 ctgacggcat tgccggaatg gcctgtcaca gggagcgtgg gcatcgacaa cagcgggcag
     8521 aagaataccg gtacggggca gttaaatggt gtcctttcct ttaataatcc tctggggctg
     8581 gctgacaact ggtttgtcag cgggggacgg agcagtgact tttcggtgtc acatgatgcg
     8641 aggaattttg ccgccggtgt cagtctgccg tatggctata ccctggtgga ttacacgtat
     8701 tcatggagtg actacctcag caccattgat aaccggggct ggcggtggcg ttccacggga
     8761 gacctgcaga ctcaccggct gggactgtcg catgtcctgt tccgtaacgg ggacatgaag
     8821 acagcactga ccggaggtct gcagcaccgc attattcaca attatctgga tgatgttctg
     8881 cttcagggca gcagccgtaa actcacttca ttttctgtcg ggctgaatca cacacacaag
     8941 tttctgggtg gtgtcggaac actgaatccg gtattcacac gggggatgcc ctggttcggc
     9001 gcagaaagcg accacgggaa aaggggagac ctgcccgtaa atcagttccg gaaatggtcg
     9061 gtgagtgcca gttttcagcg ccccgtcacg gacagggtgt ggtggctgac cagcgcttat
     9121 gcccagtggt caccggaccg tcttcatggt gtggaacaac tgagcctcgg gggcgagagt
     9181 tcagtgcgtg gctttaagga gcagtatatc tccggtaata acggtggtta tctgcgaaat
     9241 gagctgtcct ggtctctgtt ctccctgcca tatgtgggaa ctgtccgtgc agtgactgca
     9301 ctggacggtg gctggctgca ctctgacaga gatgacccgt actcgtccgg cacgctgtgg
     9361 ggtgctgctg ccgggctcag caccaccagt ggccatgttt ccggttcgtt cactgccgga
     9421 ctgcctcttg tttacccgga ctggcttgcc cctgaccatc tcacggttta ctggcgcgtt
     9481 gccgtcgcgt tttaagggat tattaccatg catcagcctc ccgttcgctt cacttaccgc
     9541 ctgctgagtt accttatcag tacgattatc gccgggcagc cgttgttacc ggctgtgggg
     9601 gccgtcatca ccccacaaaa cggggccgga atggataaag cggcaaatgg tgtgccggtc
     9661 gtgaacattg ccacgccgaa cggggccggg atttcgcata accggtttac ggattacaac
     9721 gtcgggaagg aagggctgat tctcaataat gccaccggta agcttaatcc gacgcagctt
     9781 ggtggactga tacagaataa cccgaacctg aaagcgggcg gggaagcgaa gggtatcatc
     9841 aacgaagtga ccggcggtaa ccgttcactg ttgcagggct atacggaagt ggccggcaaa
     9901 gcggcgaatg tgatggttgc caacccgtat ggtatcacct gtgacggctg tggttttatc
     9961 aacacgccgc acgcgacgct caccacaggc aaacctgtga tgaatgccga cggcagcctg
    10021 caggcgctgg aggtgactga aggcagtatc accatcaatg gcgcgggcct ggacggcacc
    10081 cggagcgatg ccgtatccat tattgcccgt gcaacggaag tgaatgccgc gcttcatgcg
    10141 aaggatttaa ctgtcactgc aggcgctaac cggataactg cagatggtcg cgtcagtgcc
    10201 ctgaagggcg aaggtgatgt gccgaaagtt gccgttgata ccggcgctct cggtggaatg
    10261 tacgccaggc gtattcatct gacctccact gaaagtggtg tcggggttaa tcttggtaac
    10321 ctttatgccc gcgagggcga tatcatactg aacagtgccg ggaaactggt cctgaagaac
    10381 agccttgccg gcggcaatac caccgtaacc ggaacgaatg tttcactttc aggggataac
    10441 aaagccggag gaaatctcag cgttaccggg acaacgggac tgacactgaa tcagtcccgt
    10501 ctggtgacgg ataaaaatct ggtgctgtct tcatccgggc agattgtaca gaacggtggt
    10561 gaactgactg ccgggcagaa cgccatgctc agtgcacagc acctgaacca gacttccggg
    10621 accgtgaatg cagctgaaaa tgtcaccttg accaccaccg atgataccac actgaaaggc
    10681 cgcagcgttg ccgggaaaac actcaccgtc agttccggca gcctgaacaa cggcgggaca
    10741 ctggttgccg ggcgcgatgc cacggtgaaa accgggacat tcagtaatac cggtgccgtc
    10801 caggggaacg gcctgaaagt caccgccact gacctgacca gcaccggcag tattaaaagt
    10861 ggcagcacac tcgatatcag cgtccgcaat gccacactgt ccggtgatgc cggtgcaaaa
    10921 gacagtgccc gcgttaccgt cagcggtaca ctcgaaaacc gcggcagact cgtcagcgat
    10981 gacgtgctga cgctcagtgc cacgcagata aacaacagcg gtaccctctc cggggcaaag
    11041 gaacttgtgg tttctgcaga cacactgacc accacagaaa aatcggtcac aaacagtgac
    11101 ggtaacctca tgctgaacag cgcgtcttcc acactggcgg gtgaaaccag tgcgggtggc
    11161 acggtgtctg taaaaggcaa cagtctgaag accacgacca ctgcgcagac gcaaggcaac
    11221 agtgtcagcg tggatgtgca gaacgcacag cttgacggaa cacaggctgc cagagacatc
    11281 cttaccctga acgccagtga aaagctcacc cacagcggga aaagcagtgc cccgtcgctc
    11341 agcctcagtg cgccggaact gaccagcagc ggcgtacttg ttgcttccgc cctgaataca
    11401 cagtcacaga ccctgaccaa cagcggtctg ttgcaggggg aggcctcact caccgttaac
    11461 acacagaggc ttgataatca gcagaacggc acgctgtaca gtgctgcaga cctgacgctg
    11521 gatataccgg acatccgcaa cagcgggctt atcaccggtg ataccggcag cgatatgcag
    11581 cgcggtatcc aggctgcaac ggctgcactt cagggcctgg tgggcggcaa tatggcaggc
    11641 gcgctggcag gtgcttcagc gccggagctg gcgaacatca tcggtcatca cgcgggtatt
    11701 gatgacaata cagcggcaaa agccattgcc catgccattc tcggtggtgt gacagcagcc
    11761 cttcagggca acagtgcggc agcaggcgca attggtgcgg gtactggtga agtgatcgcg
    11821 tcagccattg cgaaaagcct ctacccgggc gtagatccgt cgaaactgac agaagatcag
    11881 aagcaaactg taagcacgct ggcaacgctg tcagcgggta tggccggcgg cattgccagt
    11941 ggcgatgtgg ctggcgcggc tgctggagct ggtgccggga agaacgttgt tgagaataat
    12001 gcgctgagtc tggttgccag aggctgtgcg gtcgcagcac cttgcaggac taaagttgca
    12061 gagcagttgc tagaaatcgg ggcgaaagcg ggcatggccg ggcttgccgg ggcggcagtc
    12121 aaggatatgg ccgacaggat gacctccgat gaactggagc atctgattac cctgcaaatg
    12181 atgggtaatg atgagatcac tactaagtat ctcagttcgt tgcatgataa gtacggttcc
    12241 ggggctgcct cgaatccgaa tatcggtaaa gatctgaccg atgcggaaaa agtagaactg
    12301 ggcggttccg gctcaggaac cggtacacca ccaccatcgg aaaatgatcc taagcagcaa
    12361 aatgaaaaaa ctgtagataa gcttaatcag aagcaagaaa gtgcgattaa gaagatcgat
    12421 aacactataa aaaatgctct gaaagatcat gatattattg gaactctcaa ggatatggat
    12481 ggtaagccag ttcctaaaga gaatggagga tattgggatc atatgcagga aatgcaaaat
    12541 acgctcagag gattaagaaa tcatgcggat acgttgaaaa acgtcaacaa tcctgaagct
    12601 caggctgcgt atggcagagc aacagatgct attaataaaa tagaatcagc cttgaaagga
    12661 tatggaatat gattacctta cgtaaattga ttggaaacat caatatgaca aaagagcctg
    12721 agcaacaatc accgcttgaa ctctggttcg aacgtatcat agatgtgcct cttgaaaagt
    12781 taacagtgga agatctttgc cgcgctatcc gacaaaattt atgtattgat cagttgatgc
    12841 caagagtgtt ggaagttcta actaaagagc cgttagcggg tgaatattac gatggtgaac
    12901 taattgcagc tttatcaacg ataaaaggag aagatctaaa agatcagaaa agtaccttta
    12961 cccaaataag gcaacttata aaccagctag aaccgtcaga tattaacgat gatttaagaa
    13021 aagatatatt aaaaatcaat cagataattg tataactaat cccggccact gagccgagat
    13081 cttctttgtg tgccgggcat gttcagcagc ttgggggtga aagtcccctg tccagcctga
    13141 tggtggcgaa ggcgttcgcg tacgcactta accagtggcc ggcactgacg tactatgcga
    13201 acgatggctg ggtggaaatc gacaacaaca tcgctgaaaa tgccctgcgg gcggtcagtc
    13261 tgggtcgtaa aaacttcctg ttcttcggct ctgaccatgg tggtgagcgg ggagcgctac
    13321 tgtacagcct gatcgggacg tgcaaactga atgacgtgga tccagaaagc taccttcgcc
    13381 atgtgcttgc cgtcatagca gactggccgg tcaaccgggt cagcgaactg cttccgtggc
    13441 gcatagcact gccagctgaa taacacatcc ccgtcaatac ggccctcgct gtacgcttac
    13501 agaaaatgct gatgtctgta cagaaagaaa agaacgtcgc agagagtgtg gtatctgaaa
    13561 cgcataccgg cgacagcgta tatgcttccc tgtttgaaaa aattaacctg aatccggtat
    13621 ctgccctgag tgcactggat aaccctttcc ggtcagcaga taacgcgact ggcagaatta
    13681 cctccagcat acaacctgcg gtgcagtgcg cagctgctgc agcaactgag ggttcttgtc
    13741 cccggcaatc cccgtgttca ggaaatggtg gataactggc agaagagtgt aaggagtcgt
    13801 gcgctcccgg aagaggcgat gacgggctgg aacgaaggca tgatccgctt acagcagttg
    13861 gctgagcgcc tgaaccgtca ggatgaacag cggggaaaat acatgacggt cagtgaactg
    13921 aaaacggagg tgtttggcat catgcaggct tttaaccggc atatcccggc ggaagagcag
    13981 ttacgtcgct acggtgaagt ccgtaaccag aatggcagtg aacagcagca aaaacaggct
    14041 gaaatggcgc taaatcagtt aattaaccgt tatcagatga tacgtgcagg caaacaatag
    14101 tggtagccat aatgcaggag caaagcctga atcaggaaga gttattctga ctgagtttgg
    14161 ttttctggcg attcttgtga tggtgggatg tgcttggtta gctgaacagg ccttttccga
    14221 ccatgcgctt tcaccacaca gtgcttggcc gtacagtgca tcgcgcgatg ccgggctggc
    14281 cgatacgggc gcgggcggct atcccacttg taaacagcgg tgggccgacg acaccgttgg
    14341 gctgaaagcc cgtctactgc aacttcctgc cctagatatc tggacggcgt ttaaaaaaat
    14401 cgaccagtcg caggtagtgt atgaagaggc cgtgctgcgc tcgcgggtca gtgaacgaaa
    14461 tatgcaggta tcgcagaatg ggcgcgttta tccaagctat ggcggtaacg ttgatggcac
    14521 cgtcgccaat gccgccaccc ggttggcatc cggcgctaga aatatcctcg gcagcatagc
    14581 ggcatgtacg gcattcgaca gcgtgcgtta ggcactaccg atggtacagg cgcagctgca
    14641 aatagcgctg gtgatctgta ttccgctgat aacgctctgt tcggcgtggg atgtgaaagt
    14701 agtgatgacg ctgacgtttg tgcagtttgc actatttttc ctcacctttt ggtgggaact
    14761 ggcacggtgg cttgatagct ggctgctgga tgtgctctac aacagcgata cccacagtag
    14821 caggaattta gccgggatcc agaatacgca ggatgacgtg attatcaatc tggtgatgag
    14881 gttgatgttt ctggtgttgc cgacattctg gctgggggcg atgacgtggg ctggagtgag
    14941 ggttggcgtg gcgctgaatg gagcgctggc gggatgattg ggaggtgatt cgccaatctc
    15001 actttcctat acacatataa aatgtaatga aatatctctt ttttgagaat atacattcta
    15061 tatttttaac attcagtctc ttccgaacat ctgtgtcgcc tgatttccca atgatttttg
    15121 cattgccctc aatcatttta ggtcaattta cgaccaacca attaactaac tttgtgatat
    15181 gtatgggtaa caccgttgaa cgtcggctgg gtgttgttca taatcccttt aaaaggtctg
    15241 gggatg
//
LOCUS       DAFGPF010000115        15061 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFGPF010000115 DAFGPF010000000
VERSION     DAFGPF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15061
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.115"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(229..1281)
                     /gene="fbaB"
                     /locus_tag="LSX49_004061"
     CDS             complement(229..1281)
                     /gene="fbaB"
                     /locus_tag="LSX49_004061"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HBL7170397.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEESSAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            1538..2815
                     /locus_tag="LSX49_004062"
     CDS             1538..2815
                     /locus_tag="LSX49_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170398.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGAVLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVNGLTFNWAGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKVDDRDIALTQGEVK"
     gene            2812..3816
                     /locus_tag="LSX49_004063"
     CDS             2812..3816
                     /locus_tag="LSX49_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HBL7170399.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPDLIGRNILGWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAI
                     "
     gene            3813..4778
                     /locus_tag="LSX49_004064"
     CDS             3813..4778
                     /locus_tag="LSX49_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL7170400.1"
                     /translation="MSGARLHTLLPELTTRQPVMVVGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNREWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEELQDVTPFIDFGPRIGDIPDALLARIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGKQWQEKFAAPLIVRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(4752..5498)
                     /locus_tag="LSX49_004065"
     CDS             complement(4752..5498)
                     /locus_tag="LSX49_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL7170401.1"
                     /translation="MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQSLEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEDVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(5550..6368)
                     /locus_tag="LSX49_004066"
     CDS             complement(5550..6368)
                     /locus_tag="LSX49_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HBL7170402.1"
                     /translation="MQLRITSRKKFTVLLCALGLISIVAIYPRQTVNFFYSTAIQIKD
                     YIHFYGYRPVKSFAIRIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKAT
                     EGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVSASVQARLFLQTVDFSQGDFPAVL
                     DVEERGKLSAKELRKRVSQWLKMVEKRTGKKPIIYSGAVFYHTNLAGYFNEYPWWVAH
                     YYQRRPDNDGMAWRFWQHSDRGQVDGINGPVDFNVFNGTEEELQGFVDGIKETP"
     gene            complement(6433..7233)
                     /gene="thiD"
                     /locus_tag="LSX49_004067"
     CDS             complement(6433..7233)
                     /gene="thiD"
                     /locus_tag="LSX49_004067"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBL7170403.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAQRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(7230..8018)
                     /gene="thiM"
                     /locus_tag="LSX49_004068"
     CDS             complement(7230..8018)
                     /gene="thiM"
                     /locus_tag="LSX49_004068"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBL7170404.1"
                     /translation="MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTRPRAQAMSAAVEQATRSQTPWTLDPVA
                     VGALDYRRRFCLELLSHKPTAIRGNASEIMASAGVANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEVDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTL
                     ENIASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(8053..8149)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(8241..8513)
                     /gene="rcnR"
                     /locus_tag="LSX49_004069"
     CDS             complement(8241..8513)
                     /gene="rcnR"
                     /locus_tag="LSX49_004069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HBL7170405.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            8634..9458
                     /gene="rcnA"
                     /locus_tag="LSX49_004070"
     CDS             8634..9458
                     /gene="rcnA"
                     /locus_tag="LSX49_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HBL7170406.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTA
                     FWMFWRTWRGERNWLENMHEHDHEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHAND
                     IKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGTTLVVSFSLGLA
                     LTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            9677..10015
                     /gene="rcnB"
                     /locus_tag="LSX49_004071"
     CDS             9677..10015
                     /gene="rcnB"
                     /locus_tag="LSX49_004071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HBL7170407.1"
                     /translation="MTIKNKMLLGALLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAGTHWTYMGGAYVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(10097..11131)
                     /locus_tag="LSX49_004072"
     CDS             complement(10097..11131)
                     /locus_tag="LSX49_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HBL7170408.1"
                     /translation="MEIRIMLFILMMMVMPVSYAACYSELSVQHNLVVQGDFALTQTQ
                     MATYEHNFNDSSCVSTNTITPMSPSDIIVGLYNDTIKLNLHFEWTNKNNITLSNNQTS
                     FTSGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSASSSTRGSAAVQFLLCLLGG
                     KSWDACVNSYRNALAQNAGVYSFNLTLSYNPITTTCKPDDLLITLESIPVSQLPATGN
                     KTTINSKKGDIILRCKNLLGQQNQTSRKMQVYLSSSDLLTNSNTILKGAEDNGVGFIL
                     ESNGTPVTLLNITNSSKGYTNLKEIAAKSKLTDTTVSIPITASYYVYDTNKVKSGALE
                     ATALINVKYD"
     gene            complement(11147..13627)
                     /locus_tag="LSX49_004073"
     CDS             complement(11147..13627)
                     /locus_tag="LSX49_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBL7170409.1"
                     /translation="MLRMTPLASAIVALLIGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREMIKRLGINTDNFASGK
                     QCLTFKQLIQGGSYTWDIGVFRLDFSVPQAWVEELEIGYVPPENWERGINAFYTSYYM
                     SQYYSDYKASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFSGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDFAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGTGW
                     NTRFGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDNYRRDENDIYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNLRRISYTLAASHAYDENHHEEKRFNIFISIPFDWGDDV
                     TTPRRQIYMSNSTTFDDQGVASNNTGLSGTVGSRDQFNYGVNLSYQYQGNETTAGANL
                     TWNAPVATVNGSYSQSSAYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVVYDGMTPYRENYLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQPLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVN
                     VAIDKQQGLSCTITFGKEIDESKNYICQ"
     gene            complement(13643..14317)
                     /locus_tag="LSX49_004074"
     CDS             complement(13643..14317)
                     /locus_tag="LSX49_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBL7170410.1"
                     /translation="MKGLLALLISSMVLPAHAGIVIYGTRIIYPAEHKEVMVQLMNQG
                     NRSSLMQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGN
                     YISDKI"
     gene            complement(14398..14940)
                     /locus_tag="LSX49_004075"
     CDS             complement(14398..14940)
                     /locus_tag="LSX49_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7170411.1"
                     /translation="MKRSIIAAAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFE
                     AGGDSVSINMPTVPTTVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNDK
                     ITGNDKAIASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKIADGQYAIPFKAKYLKLT
                     DNSVNSGDVLSSLVMRVAQD"
BASE COUNT         3731 a         3769 c         3500 g         4061 t
ORIGIN      
        1 attttcacat cctgtcattt gttttcgatt tcaaaatata atgaaattat ttgttttcaa
       61 atgtcgagat aacgatcaca aaaacgacaa tgtgaaaatt aatcagaatg acaggcaaaa
      121 aaaacggcct cccgggggaa gccgtaacga agtgcgcgtg tttttatgcc ggatgcaacg
      181 taaacgcctt ttccgtccta cggggtggtt ctgttcgtat gaggcgcatc aggcgatagt
      241 aattttacta tcgagataaa cgtcctgtac ggcgttaatc agtttcacgc cgtcagccat
      301 cgatttcttg aacgccttac gtccaagaat cagccccatt ccgcctgcgc gtttgttgat
      361 aaccgcagta cgcactgcat cgctgaggtc agtttcaccg cctgcagcac cgccggagtt
      421 tatcaacccg gcccggccca tatagcagtt agctaactga taacgcacca ggtcaatcgg
      481 gttttcactg gtcagtttgc tgtagactcg atcgtcggta taaccgtaat taatcgcttt
      541 atagccgccg ttattttccg ccattttttg tttgacgata tctgcaccta tggttgccgc
      601 cagatggttc gcctgaccgg tcaggtcggc ggaaacatgg taatcaacgc catctttctt
      661 aaaggcggag ttacgcaaat aggcccacag cactgtcacc atgcccagct cgtgcgcacg
      721 ttcaaaagcc gcagaacttt cttcaatctg gcgacgtgac tcttccgagc caaaatagat
      781 agtcgcacca accgccaccg cgcccatgtt gaacgcctgc tccacgctgg catacagcgt
      841 ttgatcgtag gtattcgggt aacttagcgt ctcgttgtga ttaagtttga cgaggaatgg
      901 aatgcgatgc gcgtaacgcc gcgataccga tgccagcacg ccgtaagttg acgccacaca
      961 gttacagccc gcttcgatcg ccagttcaac aatgtttttc gggtcaaagt agagcgggtt
     1021 agcggcaaat gaagctccgg cagagtgctc aacgccctgg tcaaccggca gaatagaaag
     1081 atatcctgtg ccagccagac gcccggtgtt gtacaacgtc tgcatattac gtaacaccgc
     1141 tggcgggcga ttattgtcaa tcatcacgcg gtctacgtag tcatgtccgg ggagataaag
     1201 ctggtcagaa ggaatagtca tacaacggtg ctgtaaaagg ttgtcggcgt ctttgccaag
     1261 caactgcgca atatctgtca ttactatgct cccgtaaatt ccgattggat atcggctatg
     1321 gattgtcctg gcccgccttt tgcgggcaat cataatcctg gtcgttacgg gcgagttttt
     1381 ccatcttttg gatgtttttt cagcgttttc tgttggctcg attcatcaga aaaaatgtta
     1441 ccgcggtcaa gttttcaccg caaaggtatt taaaaggtat tactaagtgg tattgtcatc
     1501 gcgtacctta cattacctgt catgaaggaa ttaaaagatg aaaacaacag caaagctgtc
     1561 gttcatgatg tttgttgaat ggtttatctg gggcgcgtgg tttgtgccat tgtggttgtg
     1621 gttaagtaaa agcggtttta gtgccggaga aattggctgg tcgtatgcct gtaccgccat
     1681 tgcggcgatc ctgtcgccaa ttctggttgg ctccatcact gaccgctttt tctcggcgca
     1741 gaaagtgctg gcggtattga tgttcgctgg cgcggtactg atgtatttcg ctgcgcaaca
     1801 gaccactttt gccgggttct tcccgttact gctggcctac tcgctaacct atatgccgac
     1861 cattgcgctg actaacagta tcgcttttgc caacgtgccg gatgtggagc gtgatttccc
     1921 acgcattcgt gtgatgggca ctatcggctg gattgcctct ggtctggcat gtggattctt
     1981 gccgcaaatg ctgggttatg ccgatatctc accgactaac atcccgctac tgattaccgc
     2041 cggaagttct gctctgctcg gtgtgtttgc gtttttcctg cccgacacgc cgccaaaaag
     2101 caccggcaaa atggatatta aagtcatgct cggcctggat gcgctgatcc tgctgcgcga
     2161 taaaaacttc ctcgtctttt tcttctgttc attcctgttt gcgatgccac tggcgttcta
     2221 ttacatcttt gccaacggtt atctgaccga agttggcatg aaaaacgcca ctggctggat
     2281 gacgctcggc cagttctctg aaatcttctt tatgctggca ttgccgtttt tcactaaacg
     2341 ctttggtatc aaaaaggtat tgttgcttgg tctggtcacc gctgcgatcc gctatggctt
     2401 ctttatttac ggtagtgcgg atgaatattt cacctacgcg ttactgttcc tcggtatttt
     2461 gctgcacggc gtaagttacg atttttacta cgttaccgct tacatctatg tcgataaaaa
     2521 agctcccgtg catatgcgta ccgccgcgca ggggctgatc acgctctgct gccagggctt
     2581 cggcagtttg ctcggctatc gtcttggcgg tgtgatgatg gaaaagatgt tcgcttatca
     2641 ggaaccggta aacggactga ctttcaactg ggccgggatg tggactttcg gcgcggtgat
     2701 gattgccatt atcgccgtgc tgttcatgat ttttttccgc gaatccgaca acgaaattac
     2761 ggctatcaag gtcgatgatc gcgatattgc gttgacacaa ggggaagtta aatgaaaaca
     2821 gaacgtattc tcggtgctct ttatgggcag gcgttagggg atgcgatggg gatgccctcc
     2881 gagctttggc cgcgcagtcg cgtcaaagca cactttggct ggattgaccg ttttctgcct
     2941 gggccaaagg agaataacgc ggcctgttat tttaaccgcg ccgaattcac cgacgatacc
     3001 tcgatggcgc tgtgtctggc ggatgcgtta ctggaacgtg aaggcaagat cgatccggat
     3061 ctgattgggc gtaatattct cggctgggcg ctgcgtttcg acgcctttaa caaaaacgta
     3121 ctaggtccga cctcgaagat tgcgcttaac gccattcgcg acggtaaacc cgttgctgaa
     3181 ctggaaaata acggcgtgac caacggcgca gcgatgcgcg tctcgccatt aggttgtttg
     3241 cttccggcgc gcgatgttga ttcctttatt gatgatgtgg cgctggcctc cagcccgacc
     3301 cataaatccg atctggcggt tgcgggggcg gtagtcatcg catgggcgat ttctcgtgcc
     3361 attgacggag aaagctggtc agcgattgtt gattcactgc cttcaattgc gcgacatgct
     3421 caacaaaaac gcatcactac cttcagcgcc tcactggcag cacgtctgga gattgcgctg
     3481 aaaattgtgc gcaatgccga tggcaccgaa tccgccagcg aacagcttta ccaggtcgtt
     3541 ggcgcaggta ccagtactat tgagtccgtt ccgtgcgcca ttgcgctggt tgaactggca
     3601 caaaccgacc cgaaccgttg cgccgtcctg tgcgctaacc ttggcggcga cacagacacc
     3661 atcggtgcta tggcgacggc aatttgcggc gcgttgcatg gcgttaacgc tatcgatcct
     3721 gcgttaaagg cggaactgga tgcagtaaat cagcttgatt tcaaccgcta tgccacagcg
     3781 ctggcgaaat atcgtcaaca acgggaggcg atatgagcgg cgctcgatta cacacgctgc
     3841 tgcctgaatt aaccacgcgt cagccagtga tggtcgtcgg cgcggcggtc attgatgtga
     3901 tcgccgacgc ttacgctctg ccctggcgtg ggtgcgatat cgaactgaaa cagcagagcg
     3961 ttaacgttgg cggctgcgca ctgaatattg ccgtggcgtt aaagcgcctc ggcatcgaag
     4021 cgggtaatgc cctgccgctc ggtcagggcg tgtgggcgga gattattcgc aaccggatgg
     4081 cgaaagaggg gttaatcagc ctgatcgata acgctgaagg cgataacggc tggtgtctgg
     4141 cgctggttga gccggatggc gaacgcactt ttatgtcatt cagtggtgtg gaaaatcagt
     4201 ggaatcgcga atggctggcg cgattaaccg ttgcgcctgg cagcctgctc tatttttccg
     4261 gttatcaact ggcctcgccc tgcggcgaat tgttagtgga atggctggaa gagctgcaag
     4321 acgtgacgcc atttatcgat tttggcccac gtattggcga tatcccggat gcattactgg
     4381 cgcggatcat ggcctgtcga cctttagtgt cactcaatcg tcaagaggct gagattgccg
     4441 ccgaacgttt tgctttatcc gcagagataa caacacttgg caagcaatgg caggagaaat
     4501 ttgccgcgcc gttgatcgtt cgtctcgata aagagggcgc atggtatttc agcaacgacg
     4561 cttctggctg cattccggca tttccaacgc aagttgtaga caccattggg gcgggcgaca
     4621 gtcatgccgg cggcgtactt gccgggctgg cctctggtct gccactggcg gatgccgtat
     4681 tactgggcaa tgcagtggcg tcgtgggttg tcgggcatcg gggcggtgat tgtgcgccaa
     4741 cgcgcgagga actactcctc gcacacaaaa acgtatagat cgctgcgaca gtggctgatg
     4801 ctgtactcaa taggccgttg ctgttggtca agcgccactt gcttgatcac cagcaccggt
     4861 attttgctat ctaactgaat atgtgactga aactcggcat ccggcatccg ggcgctaacg
     4921 cgggaacgcg tacgttgtgg gtaaatgtgc tggctgcgga agtagtcata aagagaaatc
     4981 ccgatggcat caacatcatg aattaaatgt gccggaaccc acgattcctc aatcgatacc
     5041 gcctcttcat cgacatagcg aatacgctta agcaaaaaaa catcacttcc tgcctcgacc
     5101 gccagctgct gcgcgacgtc ttcgggacat ttcacgacac gcttgttaac ccatagcgta
     5161 tcgggctttt tcccgcgcaa caccacctgc tgagaaaaac ctcgcgcttc tttcaacgag
     5221 tattcgaaga tgttgttgat ctgcgtgccg taaccacgcg aacgcgtcac cacgccctct
     5281 tcttccagcg actgcatcgc cttgcgcacc gtaatgcgcg aaacgccggt taactgactt
     5341 aaatcacgct caccgggcaa aatattgcca tgctccagca ccccgctgcg cacggcattt
     5401 tttaccgttt cggcaaactt aatataaagc ggcgtgttat ccgccgctaa aatacgctcg
     5461 ttcagttggg caatcagctg ggtatgcgct tgttccattt gtctttttcc tgccggggaa
     5521 tctggtggga gtatatcact gcttcttatt taaggcgttt ctttaatccc atcaacgaat
     5581 ccctgcaact cctcctctgt gccattaaac acattaaaat ccaccggacc attaatgcca
     5641 tcgacctgtc cacggtcgga atgctgccag aagcgccagg ccatgccgtc attgtccggg
     5701 cgacgttgat aatagtgagc cacccaccac ggatattcat tgaaatagcc cgccagattg
     5761 gtgtgataaa aaacggctcc tgagtaaata atcggctttt ttcccgtacg tttttcgacc
     5821 atttttagcc actgacttac ccgcttgcgt aattcttttg ccgataattt tcctcgctct
     5881 tctacgtcca gtaccgcagg gaaatcgcct tgtgagaaat ccaccgtttg cagaaataat
     5941 cgcgcctgaa ctgaagcgga tactgacggg gagaaataat gatacgcccc gcgcagcagg
     6001 ccattttccc ggcttagttg ccagttacgc gaaaaatagg ggtccaccag cttttcgcct
     6061 tccgtcgcct taataaaagc aaactgtaag cggataccgt tgtcgcgcat ttttgccacc
     6121 cgctgccagt cgatccgctc ctgccagcgc gaaacatcta ttccgtgaat ggtgtaactg
     6181 gcaggaatgc gaatagcgaa agatttaacc gggcgataac cgtagaagtg gatgtagtct
     6241 ttaatctgaa ttgctgtcga atagaaaaaa ttcaccgtct gacgcggata aattgcaacg
     6301 atggaaatta gcccaagagc gcataataaa acggtgaatt tttttcgact ggtgattctc
     6361 aactgcattg gtttcatccc tgaatgtcag caccaaaggc tgacaataac caaagcagct
     6421 atagtacggt gctcaccacc aggcgtggaa gtggtgaacc ggaccaatac cgtgaccaac
     6481 ttccagcgtg tcggcctggg ctaatgccga tgaaagccag ctttttgcct cctgtacggt
     6541 gtcagcccag tttgtatggc gcgggcgcag tgcagccaac gccgcagaga gcgtacaacc
     6601 agtgccgtga gtgtttttgg tcataatgcg ctgtgcggta aaccgttgtt caccctcgcg
     6661 ggtaaacagc cagtccgggc tttgctcatc atccagatga ccacctttca ttagcactgc
     6721 gccacagccc atcgccaaca gcgatcgccc ttgttccagc atttcctgtt cggtgcgcgc
     6781 gtgtggcgcg tcgagcaagg cggctgcttc gggcaagttt ggcgttatta atgaaacctg
     6841 tggcaataat cgactgcgta gcgtggcaac tgccgaaggt gaaagcagcg ggtcgccgct
     6901 ttttgccagc ataacggtgt cgagtaccac gttttggatc tgataacgtt gcaaccgttc
     6961 tgccaccgct tcaacaatat cggtttccgc caacataccg attttagtgg tgtcgattcg
     7021 cacatcgctg aacaccgaat cgagctgggc ggcgacaaaa tcaggctcaa tgcgatacac
     7081 cgactgtaca ccacgggtat tttgcgccac cagtgcagta ataactgagc aaccataagc
     7141 gccaagtgcc gagaaggttt taagatcggc ctgaatcccc gcaccaccac tcggatcagt
     7201 accggcaatc gtcagagcgt taattcgttt catgcctgca cctcctgcgt caattgccag
     7261 agcgcatcaa ggaaatgtgg aacaaaactg cctggcccct cgcttctggc gactgcgcgt
     7321 tctccggctt gtttcatcca gtgacaggca gatgcgatat tttccagcgt atcgcctggt
     7381 agcgcacaac aggcagcgac aaccgccgat agtgcacagc cagttcctac cactttggtc
     7441 attaacggat cgccaccgtg aatgccaatg atacgatgtc catcggtaac ataatccacc
     7501 tcgccagtga ccacgacgat tgcgccagtt tcccgtgcca gtgtttgtgc agcaggtatc
     7561 gcgttagctg cggcatcagt ggtatccact ccccgtccac cattagcaac gccagctgat
     7621 gccatgattt ccgaagcatt accacgtatg gcggttggct tatgggacag aagttccaga
     7681 caaaaacggc ggcgataatc gagcgcacca accgcaaccg gatcaagcgt ccagggcgtt
     7741 tgtgatcgtg ttgcttgctc aacggcagca ctcatcgctt gcgctcgtgg ccgcgtcagc
     7801 gtgccaacgt taatcaacaa ggcactggcg atagccgcaa actgactggc ctcttcggtt
     7861 tcgataacca tcgctggcga tgcgccgagc gccagcaagg tattggcagt aaaagtttgc
     7921 accacatcgt tggtcatgca gtgcacaaga ggggaatgtt ggtgaaaaag gtgtaacgcg
     7981 tgcgcagatt gcgctgaact cagcaggtcg acttgcatag tttgctcctg ccataacgtg
     8041 aagaagcaat gacctggtgg tccgtgactt ccctacgctg gcattatcca gatcaggtga
     8101 tacgggtatt tctcagcctt cacaaagaag ggcaccccga gtcgtttggt tgcgataata
     8161 aatcgcagag gaggatggta atgtccagcg cacgcgttgt aaacggggaa aaacggcggt
     8221 attacaataa cgttgtgaaa ttatttgata taagaatcca gcaccttcag aacgacatcc
     8281 agatcttctt cacgttttag ctcatccccc tggtgaacga tgtgttccgt cagatggcct
     8341 ttaatcactt cccgcatcag accgtttacc gcgccacgga tagcagcaat ctgttgtaaa
     8401 actgcagcgc attcatgcgg ttcgtcgagc attttcttga gcgccacgac ctggccctga
     8461 atcttactgg cacgcgcttt cagtttctgt ttatcacgga ttgtatgaga catggcaaca
     8521 cctggttaac aagaatatga aaaatcatag cactattaat ctactggggg gtagtatcag
     8581 gtactggggg ggagtagaat cagattgccg aattaatact aagaattatt atcatgaccg
     8641 aatttacaac acttcttcag caaggaaacg cctggttctt catccccagc gccatcttac
     8701 ttggtgcgct tcatggtctg gaaccggggc actcaaaaac gatgatggcg gcgtttatca
     8761 tcgccatcaa aggcaccatt aaacaggcgg tgatgctcgg actggcagca actatttcgc
     8821 ataccgcagt ggtctggtta attgcctttg gcgggatggt gatcagcaaa cgctttactg
     8881 ctcaatcagc agaaccgtgg ctccagttga tttccgcagt gatcattatt agcaccgcgt
     8941 tctggatgtt ctggcgtacc tggcgcggcg aacgcaactg gctggagaat atgcacgagc
     9001 atgatcatga gcatcatcac cacgatcacg aagatcacca cgaccatgga catcatcacc
     9061 atcacgaaca tggcgagtat caggatgccc atgcacgagc ccatgccaat gacattaaac
     9121 gacgctttga tggtagagag gtcaccaact ggcaaatttt gctatttggc ttaaccggtg
     9181 gccttatccc ctgcccggca gcaattaccg tgctgttgat ttgcattcag ttgaaagccc
     9241 tgacactggg cacaacactg gtcgtcagtt tcagcctcgg cctggcgtta acgcttgtca
     9301 ccgtaggcgt tggcgcagca atcagcgttc agcaggtcgc aaaacgctgg agcggattta
     9361 acactctcgc taaacgcgct ccctattttt ccagtctgtt gattggctta gttggtgtgt
     9421 atatgggcgt acatggcttc atgggcataa tgcgataact caatccttta ggcttgcatg
     9481 ttatcttcag cccaggatga ttcttaaatc agctatttcc gctgactctc tgctcgctaa
     9541 ggatgctttt agggcatcct ttcatttaca ctttttacga aatcatggga tcactaacaa
     9601 aatatcgctt gtcagttata ttgtatggca ggaaagatat gcgactgata ttacagatcc
     9661 ccaaagtgga gagtttatga ccattaaaaa taagatgttg ctgggtgcgc ttttgctggt
     9721 taccagtgcc gcctgggccg caccagccac cgcgggttcg accaatacct cgggaatttc
     9781 taagtatgag ttaagcagtt tcattgctga ctttaagcat ttcaaaccag gtgacaccgt
     9841 cccagagatg taccgcaccg atgagtacaa cattaagcag tggcagttac gtaacctgcc
     9901 cgcgcctgat gccgggacgc actggaccta tatgggtggc gcgtacgtgt tgatcagcga
     9961 caccgacggt aaaatcatta aagcctacga cggtgagatt ttttatcatc gctaaaaaaa
    10021 agccccctcg gagagagggg ggaatgcaga caccttaata tttttattat tagccacttg
    10081 ctcgtcttgc ttgttattag tcgtatttca cgttgattaa tgcggttgcc tccagtgcgc
    10141 cagatttaac tttgtttgta tcgtagacgt agtaactggc cgttatcgga attgaaaccg
    10201 ttgtatctgt aagttttgac tttgccgcaa tttcttttaa atttgtatat cctttactgc
    10261 tgttagtgat atttaaaagt gtgactggcg taccattact ttcaagaata aatcctacgc
    10321 cattatcttc cgcacctttc aggatcgtgt tgctgttggt taacaagtca gaacttgata
    10381 aatacacctg cattttccgt gatgtttgat tttgttgacc taataaattt ttacaacgca
    10441 gaataatatc ccctttttta ctatttattg ttgttttgtt acctgtggct ggtaattgtg
    10501 aaacgggaat actctctaac gtaattaata aatcgtccgg tttgcaggtt gtggttatcg
    10561 ggttgtatga caatgtcaga ttaaaggaat agacacctgc attttgtgcc aatgcatttc
    10621 tgtagctatt tacacatgca tcccatgact taccacctaa taaacacagt agaaattgta
    10681 ctgcggcact cccacgtgtc gatgatgaag cactggataa tgtcgcaact ccattaatca
    10741 tcactgaacc accgcccccc gcagaaacat tcacttttgc attactggcc gcaggtgtca
    10801 ccgttaccga ataaccactg gtgaaactgg tctgattatt tgacaatgta atgttgtttt
    10861 tatttgtcca ttcaaaatgt aaatttaatt taatggtatc gttataaagt ccaacaataa
    10921 tatccgacgg gctcataggg gtgatagtat ttgtactcac gcatgacgaa tcattaaaat
    10981 tatgctcata tgtcgccatt tgtgtttgag taagtgcaaa atccccctga acaaccaaat
    11041 tgtgctgaac agataactca ctataacatg ccgcatagct cacaggcata accatcatca
    11101 ttaatataaa tagcattatg cgaatttcca tagaaccacc tgactattac tggcaaatat
    11161 aatttttact ttcatcaatc tctttaccga aggtgattgt gcatgaaagc ccttgttgct
    11221 tatcaattgc cacattaacc gatggcggta cttcattggt gcgaataaat aactggcttc
    11281 cctggccgac aacaccaata ttatgaccat ggatatcatt gacttcataa ccaaacgtta
    11341 atggttgccc atccgctctt aatgctttta taaaccatgg cttgcgctga tcggtatcaa
    11401 aattaaccag tacaaccgcg ccgcgataag gggcggcaat tttccggttg ccacgtaatt
    11461 ctgcttcgct atcgctttgt gacacatcca acatcaggta attttcccga taaggtgtca
    11521 ttccgtcgta taccaccact ccattacggt ttgttgtgcg atatttttgc ccattgacat
    11581 aagcatcttt aattcctggc gcattcatca cagcaaacgt ttcagaaaga cggtttgcca
    11641 gattaacgcc acccgaccag gcgacaatgc cccctgaaac actggctcca gcctgtcgat
    11701 aagcactcga ctgactataa ctgccattca ctgtcgcaac cggcgcgttc caggttaaat
    11761 tcgccccagc tgtcgtttca tttccctgat actgataact caggttgacc ccatagttaa
    11821 actgatcccg gcttccaacg gttcctgata atcccgtatt atttgaggca accccctgat
    11881 catcaaacgt cgttgagtta gacatatata tttgccgacg aggcgtcgta acgtcatcac
    11941 cccaatcaaa gggaatcgat ataaaaatat taaaacgttt ctcttcatga tgattctcgt
    12001 cataagcatg gcttgccgcg agggtatagc ttatccttcg caggttgttg gaataactca
    12061 actgataatc cttactgctg ccgctacgcc cccagtaatc tcgccataac gtacttaagg
    12121 acacagaacc ccagccttct ggcaatgact gactcatatt ggcagaaaag ctatttttac
    12181 ggccaaaatc gttctggtaa taatcggcaa tgtcatagat atcgttttca tcacggcgat
    12241 aattatcttt attgtttgcc catacgtgat cattaaatgt ccgataatca cgcgacgaat
    12301 aacgccaggc cgccagacca aaacgtgtcg acgtttggct cacaaatttg ttgtaggcaa
    12361 tttgataact ttgcccgtca aacacatcgc cgttgtcttg tttactatgc gactttgtgg
    12421 catcgacgga aatggcacca aagcgtgtat tccagccagt ccccaaagtg aacgcgtaat
    12481 aattattcgc gaccatcgag ccaccataca gcgttaataa gttattaaaa ccatactgat
    12541 aacccgcctg gacaaaatca ctttgtttgc tcgccccttc aatatggcta cgacccgccg
    12601 caaaatcata tttcgacacg ccgggttgca gcatatttgg taccgctgca taaggcacca
    12661 gataggtggt taccgaaccg tccgcctctt tcacgctaac atcaagatcc gctccaccac
    12721 cggccaactg caaatctgta atcgcaaacg ggcctggagg aacctctttc tgataaacca
    12781 caaaaccatt ctgttcaata gttaccagcg cgttactctg agcaatcccc tgcactcgtg
    12841 gcgtaaaatt ttgtttcgag ttaggcaaca tctgcatatc acgaaacaac cgcacaccgc
    12901 tgaagcgaac agaatcaaaa atatcgcttg atgtgtacat atcacccaca cgaagcgtgc
    12961 cgagaagttg ggcaaatcca cgttccagat acagggtatt gctcttccac acccctggat
    13021 tgttatttgt tttactgaaa ctggcatcag aatgcagttg ccaccccaat aaatttaacc
    13081 cgctgttaaa acgtacatat gtactcttgc tattaccgga cgctttataa tcgctgtaat
    13141 actgactcat ataataagag gtataaaacg cattaatacc ccgctcccag ttttcaggtg
    13201 gtacatagcc aatttccagt tcttccaccc aggcttgcgg gacactgaaa tcgagacgaa
    13261 aaactccgat atcccaggta tagctcccgc cctgaataag ttgcttaaat gttaaacatt
    13321 gcttaccgct ggcaaagtta tcggtattaa tgcctaaccg cttgatcatt tcccttgata
    13381 aacatgtttc ttgcgggttg tctttaacaa tgatctcata tttcccacgc cattgcttat
    13441 tgacataaat atcgatgtca tactgccccg gcaagggttg attatcatca agacgaatat
    13501 ttgcaacctg ctggtctttc attccaccta tcatgaaatg ggtatcaaag gtttcttcag
    13561 ctgcataagc ttcaatgccg atcaataacg ctacgattgc tgatgcaagt ggggtcattc
    13621 tcaacatagg cagctcctgc aattaaattt tgtcactaat atagttgcca tggtcatcga
    13681 taatggtcag atgccagtta tttgcattat tacttttgac attaacactc tgactttcta
    13741 agggggcaat cataatagtt tcataattga ctttgacatt attagctttg acatccgaaa
    13801 tcgtcaccca attagctgag tcatttttta tcaccaatcc attgccactg cgatttacca
    13861 gtaacttttt aaaggtcgct ttatttaccg gagcaatacc cgctggccgg taaaacaact
    13921 taattctgtt ttgcatcgca aacttcagtg cattcttacc ttcttgttct ggactatttg
    13981 gtggaatatc cagaacattc agataaaaaa tactctcttt attagtgggt agtttattcg
    14041 gcataatttt aatttttact tgctgcccgg aatttgcccc tatttttgcc actggtggcg
    14101 ttaacatgaa aggaacctga attttttctg gtggtaatga cgtatcgcca tcatcaatcc
    14161 acgcctgcat cagcgaagaa cgatttccct ggttcatcag ctgcaccatc acttctttgt
    14221 gctctgccgg gtaaataata cgcgtcccgt agataacaat accggcatgt gcaggaagga
    14281 ccatagaaga aatgagtaaa gctaataatc ctttcatctt aatgcctctt aaattaaaag
    14341 gccgccatgg ggatagcggc catgttaatt acctgaagaa tcttgcaatt ttatttatta
    14401 atcctgcgcc acacgcataa ccagggaaga taacacatca cctgaattca ctgagttatc
    14461 tgtcagtttc aggtattttg ctttaaacgg aatggcatat tgaccgtccg ctattttata
    14521 actctcgatg ttgaaaggtg cagaaacatc caggacatcg ctgttatcac ctaaatagag
    14581 ataataaccc acggtatcgt tgctactggc tatcgcctta tcgtttccgg ttattttatc
    14641 gttggtaatc aacgagagtt ttacaccagc aacttctttc ggacagctaa tttttaacat
    14701 gctgctggtt acaccgactg catcatcata ggtcgagtat ttagctttac cttcaaagac
    14761 agtggttggt acagttggca tattaatact tactgaatcg ccacccgctt cgaatttaca
    14821 cggagattct gcaatattcc ctttaatggt taatgttccg gtatcaacgt ctgcggcaaa
    14881 taccccagcg ctcataaaaa aagaagaaaa aacagcggca gcaataattg aacgtttcat
    14941 aatatgctcc ttaataaaat ctatttttgg ttgttaagag tctgtatctc ttggaaacaa
    15001 atttctcaca ccaaaaaagt tgccgcaatg taaacacatt gttttattga tttaaagcaa
    15061 a
//
LOCUS       DAFGPF010000116        15009 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFGPF010000116 DAFGPF010000000
VERSION     DAFGPF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15009
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.116"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(32..2311)
                     /gene="maeB"
                     /locus_tag="LSX49_004076"
     CDS             complement(32..2311)
                     /gene="maeB"
                     /locus_tag="LSX49_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HBL7170412.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRNDR
                     MPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
     gene            2600..3550
                     /gene="tal"
                     /locus_tag="LSX49_004077"
     CDS             2600..3550
                     /gene="tal"
                     /locus_tag="LSX49_004077"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HBL7170413.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            3570..5573
                     /gene="tkt"
                     /locus_tag="LSX49_004078"
     CDS             3570..5573
                     /gene="tkt"
                     /locus_tag="LSX49_004078"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL7170414.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVVHEIDGH
                     DPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEKYRESVLPSNVSARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(5650..6693)
                     /locus_tag="LSX49_004079"
     CDS             complement(5650..6693)
                     /locus_tag="LSX49_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HBL7170415.1"
                     /translation="MRYRIFLLFFFALLPMSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQMIQEGRAITLRDGNQTISLSGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSL
                     DPLRREVNVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPQASRPVRLRLPFNNGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(6819..7394)
                     /gene="nudK"
                     /locus_tag="LSX49_004080"
     CDS             complement(6819..7394)
                     /gene="nudK"
                     /locus_tag="LSX49_004080"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HBL7170416.1"
                     /translation="MTQQITLVKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNAKKKTVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPEVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDSQRANAGGGVEDEDIEVLELPF
                     SQALEMIKTGEIRDGKTVLLLNYLQMSHLMD"
     gene            complement(7462..9441)
                     /gene="aegA"
                     /locus_tag="LSX49_004081"
     CDS             complement(7462..9441)
                     /gene="aegA"
                     /locus_tag="LSX49_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HBL7170417.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDAALSGMAKSRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRAD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVAVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLNSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRRPVPVEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            9647..11347
                     /gene="narQ"
                     /locus_tag="LSX49_004082"
     CDS             9647..11347
                     /gene="narQ"
                     /locus_tag="LSX49_004082"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HBL7170418.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQM
                     SSELHKLYRSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGDNWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            11511..14624
                     /gene="acrD"
                     /locus_tag="LSX49_004083"
     CDS             11511..14624
                     /gene="acrD"
                     /locus_tag="LSX49_004083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HBL7170419.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVA
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(14723..14782)
                     /gene="ypfM"
                     /locus_tag="LSX49_004084"
     CDS             complement(14723..14782)
                     /gene="ypfM"
                     /locus_tag="LSX49_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HBL7170420.1"
                     /translation="MIERELGNWKDFIEVMLRK"
BASE COUNT         3517 a         3980 c         3924 g         3588 t
ORIGIN      
        1 attcagggta agcgtgagag ttaaaaaaga attacagcgg ttgggtttgc gcttcaacca
       61 cggccagcgc caccatgttg acgatacgac gtaccgatgc gatcggcgtt aacacgtgaa
      121 ccggcttcgc cacccccatc agcaccgggc cgacagtcac accttccgag ctggaaacac
      181 gcagtaagtt gtaactaatg cgggcagctt ccatgttcgg catcaccaga atattagcgg
      241 aacctttcaa agggctgtcc ggcatacggt cgttgcgaat cgcttccacc agcgctgcat
      301 cgccgtgcat ttcaccatca atcatcagtt ctggcgcacg ttccctgacc agttccagcg
      361 cctgacgcat tttgctcgac gacgggcagt cagaagaacc aaagttggag tgcgacaaca
      421 gagccacacg cggctcaata ccaaaacgac gaacagtttc tgccgccatc aaggtgatct
      481 ccgccagctc ttctgcatca ggctcatcat tgacgtaggt atcggcaata aaggtgttac
      541 cactcggcaa cagcagcgcg ttcattgcac ctgcggtgtg aacgccatcg cgataaccaa
      601 agacattttt caccacgcta aagtgttcat gataatcgcc caccgtaccg caaatcattg
      661 catcggcttc gccacgctga accatgatcg cgccgatcac tgtcgggtta ctgatcagcg
      721 cacgctgcgc ctgctcctga gtgacaccgc gacgcttcat gatctggaag tattcggtcc
      781 agtactcctt aaagcgcgga tcggattcgt tattgacgat ctcaaaatca acgcccgcct
      841 tgatctgcaa gcccagtttc tgaatgcgca tttcgatcac gttcggacga ccaataagga
      901 tcggtttcgc cagtcccagc gttaccagtt cctgagtggc atgtagaacg cgcgcctctt
      961 ccccttctgg cagaactacg cgcttcggcg ctttgcgagc ctgggagaaa atcggcttca
     1021 taaacaggtt ggttttgtaa acgaactccg tcagcttgtc gatgtagacg tcgaaatcag
     1081 caatcggacg cgtcgccacg cccgactcca tcgccgcttt cgccaccgca ggagcgatct
     1141 taacgatcaa gcgcggatca aacggttttg gaatgatgta ttccggacca aagctcagat
     1201 cctgatcgcc atacgctgaa gccaccactt cactctgttc cgcatgggcc agttctgcaa
     1261 tcgcgcgtac cgccgccagt ttcatctctt cgttgatggc ggttgcgcca acgtccagcg
     1321 cgccacggaa gataaacggg aagcaaagga cgttgttcac ctggttcggg tagtcggaac
     1381 gaccggtaca gatgatggca tccggacgca cttctttcgc cagcggcggc agaatttccg
     1441 gttccgggtt cgccagcgcc aggatcattg gcgcacgggc cattttcttc accatttcct
     1501 gggtcagcac tttcgggccg gaacagccga ggaaaatatc cgcgccttca atcacatcat
     1561 cgagggttcg tttgccgtca tccaccaccg catatgcggc tttggtttcc gccatgtttg
     1621 gctcacggcc ctgatagata acgccttttg aatcgcaaac cacgatgtta tgtttttgca
     1681 gacccagcgc taccagcagg ttcatacagg cgattgctgc ggcacccgcg ccagaaacca
     1741 ccatccgcac gtcggagatg tttttctcca ccacgcgcaa gccgttgagg atggcggcag
     1801 tgctgataat tgccgtgccg tgctgatcgt cgtggaatac cggaatattc atccgctcgc
     1861 gcagtttctg ttcaatatag aaacattctg gcgctttaat gtcttcgagg ttgatgccgc
     1921 cgaaggtcgg ttcgagcgca gcgacgactt caataaattt gtccgggtcg agttcatcaa
     1981 cttcaatgtc aaatacatca atcccggcga atttcttaaa cagaacgccc ttgccttcca
     2041 tcaccggttt gcctgccagc gcgccaatgt tgcctaaccc cagcaccgcc gtaccgttag
     2101 agatcaccgc taccaggtta ccgcgcgcgg tatatttgta ggcttttaac gggtcttttt
     2161 cgatttcaag acaaggtgcg gcaacgcctg gtgagtaggc cagcgccaga tcgcgctgcg
     2221 ttgccagagg cttggttgga gaaacctgga ttttccctgg aactggaaat tcatggaaat
     2281 caagtgcact ttgttttaac tggtcatcca tttggttgtt cctttcacgt aacgttcaca
     2341 aataaattgt gtgggcaaca gcccctgccc acaacgtggc gcacattatt accctgccgg
     2401 agtctacaga ctttgagcaa gtccaaactc tcaccattaa tataatgttt tggtaataat
     2461 catataacac tgatgttacc tgcttaatcc agcaatacca tgcctgtctg ctatgctttt
     2521 ttgatgcgtt tagcgaaatt tctcagaagt gtgaattaac gcactcatct aacactttac
     2581 ttttcaagga gtatttccta tgaacgagtt agacggcatc aaacagttca ccactgtcgt
     2641 ggcagacagc ggcgatattg agtccattcg ccattatcat ccccaggatg ccaccaccaa
     2701 tccttcgctg ttactcaagg ctgccggatt atcacaatat gagcatttaa tagacgatgc
     2761 tatcgcctgg ggtaaaaaaa atggcaagac ccaggaacaa caggtggtcg cagcgtgtga
     2821 caaactggcg gtcaatttcg gtgctgaaat tctcaaaatc gtacccggtc gcgtgtcaac
     2881 agaagttgat gcacgcctct cttttgataa agaaaagagt attgagaagg cgcgccatct
     2941 ggtggatttg tatcagcaac aaggcgttga gaaatcgcgc attctgatca agctggcttc
     3001 gacctgggaa ggaattcgcg cggcagaaga gctggaaaaa gaaggtatta actgcaacct
     3061 gacgctgctg ttttcttttg cacaggcgcg ggcctgtgca gaagcaggcg tttttctgat
     3121 ttcgccattt gtcgggcgta tttatgactg gtatcaggca cgcaagccga tggacccgta
     3181 tgtggtggaa gaagatccag gcgttaaatc agtacgcaat atctacgact actataagca
     3241 acaccactat gaaaccattg tgatgggcgc gagcttccgt cgcaccgaac aaatcctcgc
     3301 cttaaccggc tgcgaccgac tgactatcgc accgaatttg ctgaaggagc tacaggaaaa
     3361 agtttcgcca gtggtacgta aattaatccc accttctcag acgttcccac gcccagctcc
     3421 catgagcgaa gcagagttcc gttgggagca caatcaggat gcgatggcgg tagaaaaact
     3481 gtctgaaggc attcgtctgt tcgccgttga tcaacgcaaa ctggaagatc ttcttgccgc
     3541 caaactataa accagccacg gagtgttata tgtcccgaaa agaccttgcc aatgcgattc
     3601 gcgcactcag tatggatgcg gtacaaaaag ccaattctgg tcatcccggc gcgccgatgg
     3661 gcatggctga tattgccgaa gtgctgtgga acgattttct taaacataac cctaccgacc
     3721 caacctggta tgatcgcgac cgctttattc tttccaacgg tcacgcgtcg atgctgctct
     3781 acagtttgct gcatctgacc ggttacgacc tgccactgga agaactgaag aacttccgtc
     3841 agttgcattc gaaaacccct ggtcacccgg aaatcggtta tacgccaggt gttgaaacca
     3901 ccaccggtcc tcttggacaa ggtttggcga acgccgtcgg gctggcgata gcagagcgta
     3961 cgctggcggc gcaatttaat cagccggatc atgaaattgt cgatcacttc acctatgtgt
     4021 ttatgggcga cggctgcctg atggaaggta tctctcacga agtctgttcg ctggcgggca
     4081 cgctggggct gggcaagctg attggttttt acgatcacaa cggtatttcc atcgacggtg
     4141 aaaccgaagg ctggtttacc gacgatacgg caaaacgttt tgaagcctat cactggcatg
     4201 tggtccacga gatcgacggc cacgatccgc aggcggtgaa ggaagcgatc cttgaagcgc
     4261 aaagcgtgaa agataagccg tcgctgatta tctgccgtac ggtgattggc tttggttcgc
     4321 cgaataaagc aggtaaggaa gaggcgcacg gcgcaccgct gggggaagaa gaagtagctc
     4381 tggcacggca aaaactgggc tggcaccatc cgccatttga gatccctaaa gagatttatc
     4441 acgcctggga tgcccgcgaa aaaggcgaaa aagcgcagca gagctggaat gagaagtttg
     4501 ccgcctataa aaaggctcat ccgcaactgg cagaagagtt tacccgtcgg atgagcggcg
     4561 gtttgccgaa ggactgggag aaaacgactc agaaatatat caatgagttg caggcgaatc
     4621 cggcgaaaat cgctacccgt aaggcttcgc aaaatacgct taacgcttac gggccgatgc
     4681 tgcctgagtt gctcggcggt tcggcggatc tggctcccag caacctgacc atctggaaag
     4741 gttctgtttc gctgaaggaa gatccggcgg gcaactacat tcactacggg gtgcgtgaat
     4801 ttggtatgac cgctatcgcc aacggcatcg cgcaccacgg cggctttgtg ccgtataccg
     4861 cgacgttcct gatgtttgtt gaatacgccc gtaacgccgc gcggatggcg gcactgatga
     4921 aagcgcggca gattatggtt tatacccacg actcaattgg tctgggcgaa gatggtccga
     4981 cgcaccaggc tgttgagcaa ctggctagtc tgcgcttaac gccaaatttc agcacctggc
     5041 gaccgtgcga tcaggtggaa gcggcggttg gctggaagct ggcggttgag cgccacaacg
     5101 gaccgacagc actgatcctc tccaggcaga atctggcaca ggtagaacga acaccggatc
     5161 aggttaaaga gattgctcgt ggcggttatg tgctgaaaga cagcggcggt aagccagata
     5221 ttattctgat tgccaccggt tcagagatgg aaatcaccct gcaagcggca gagaaattag
     5281 cgggagaagg tcgcaatgtt cgcgtagttt ccctgccctc gaccgatatt ttcgatgccc
     5341 aggatgagaa atatcgggag tcggtactgc cttcaaatgt ttctgcccgc gtggcagtag
     5401 aagcgggtat tgccgattac tggtacaaat atgttggcct gaaaggggca attgtcggga
     5461 tgacaggtta tggggaatca gctccggcgg ataagctgtt cccgttcttt ggctttaccg
     5521 ccgagaatat tgtggcaaaa gcgcataagg tactgggagt gaaaggtgcc tgatggtgat
     5581 cgccggatgc tgattgtcgg atgtgacgct ggtgcgtctt atccggtcta catgtccccg
     5641 ccattttgtt taacgggtga tccacaacgt gggccaggcg tctggcccat gccagttatc
     5701 gcaggtgggt tctgcggcgt aacgcaccag gcgaaaacgc tgaccgtcaa agcgccagcg
     5761 cgcctgaatg ccacaatcgc ttaatccgcg cccttttgct aaggtcacca gttcacgcga
     5821 tttttcatcg aatgttgcgt tcatcagttc cagttcattg gtctcctgac cgttgttgaa
     5881 cggcaaacgc aaccgtaccg ggcgcgaggc ctgcggcttt ttacgcgaca caatccatgc
     5941 caaatcaatg gtgttatagg cccctgcctc acagctaatc atcatcagcg ctttatcatc
     6001 ggtcagcgca gtgacattca cctcacgacg taacggatca agcgaacagc gcagaccatt
     6061 catccgccag tttccataat ccagcaaatc gttacgttct tcgagtgaga gtggcgtcgg
     6121 cgttgggtta accaccgcga cctctttcag cgcaggcgct ggcggtacgc tgagcggcgg
     6181 ttcgtcccct ttctttatcc acgcggtctc actgccaacg cgcttttgct gggcatcaat
     6241 aaacaacaac gccgctttta agccactcag agaaatagtc tgattgccgt cgcgtaaggt
     6301 gatcgccctc ccttcctgaa tcatctgcaa aaacgcggtg atggttgccg tatcatcggt
     6361 tactaataac catggtgaaa tccgccactt gtcaccactt aacgccaacg gctcaccatc
     6421 taacagcagc cgtggcgcta tctccccttc tgacgcatcc ggcgacttca acccgccgcg
     6481 ctcaatacgt aaaacggcat cggtatgcgc cccggcgctg cggctcaggg tcatcaccag
     6541 tccattatga tcgcccgtat tgcgcgctac acagaaattt tgattattac aggtgacctg
     6601 ccagtcggaa aacgcccgtt gcgctggtgc cgcccacacc aaagacatcg gcaacaaagc
     6661 gaaaaaaaag agaaggaaaa tgcgatatcg catggacggt acgaccccag aagttcaaac
     6721 aaacagcaca agtcgtatct tcgttgcgca ggtagcgcgg ctcaatcgga tttgtcggat
     6781 tgagccaata ataaacaacg aaatattatt gttatttttc agtccattaa atgtgacatt
     6841 tgcaaatagt taagcaataa caccgtctta ccgtcacgta tctcgccggt tttaatcatc
     6901 tccagcgcct ggctgaacgg cagctcaagc acttcaatat cttcatcttc gacaccacca
     6961 ccggcgttag cgcgctggct gtcactgtat tcggcgataa aaaagtggat tagctcagtc
     7021 acaccgcctg gcgacatata cagttcaaat aatttgcgga cttcgccaac ttcatagccc
     7081 gtctcttcaa tcgcttcttt gcgaatgcac acttccggtt cgtcgttatc cagcagcccg
     7141 gcgcaggttt caatcagttg cccgctttca ttgccattaa cccaggtagc gacgcggaac
     7201 tggcgaatca gaaccacggt ctttttcttc gcgttgtaca ggaggatcgt cgcaccatta
     7261 ccgcgatcgt aaacttcacg tttatggcgg ataacttcgc catctttgcg cgtgagatcg
     7321 taagtaatgt tgtgcagggt gaaatagtta tcggagagaa ttttgtcttt aacgagggtg
     7381 atttgttgcg tcataccgac tccacagcgc gaaatgaaca attatcttac gctgtgaagt
     7441 cgggtttgtc tgcgcaggct atcagtgaga tttgactgat tttacgccca gccagtcaat
     7501 gatcccctgt gccgcatgac gtccttctgc cattgcggta accaccagat ccgcaccacg
     7561 cacggcgtca ccaccggcga agattttcgg attcgtggtc tggtaacggt actggctttc
     7621 cacatccgcg atgatgcggc cccatttgtc taccgttaca ccgtgcgact ccagccacgg
     7681 catcccgtgc ggattgaagc caaacgccat aatcaccgca tcggctggca tgacaaattc
     7741 actgccttcc accggcactg gacgccgacg tccctgggca tccggctcgc caagacgcgt
     7801 gcgcaggaaa cgaatcccgc agacgtgacc ttgttcattc agctcaagcg ccaccggctg
     7861 gacgttaaat tcgaagttgg ccccctcttc acgggcgttc ttcacctctt tcttcgagcc
     7921 tggcatgtta gcttcatcac gacgataagc gcaggtgacg ttactcgcgc catggcgcag
     7981 cgcggtacgc acacagtcca tcgcggtgtc gccgccgccc agtaccacga cgttaagtcc
     8041 ggcggtattg ataaacggct cttccggtag ctcttcgagt cccatcacct gtttagtgtt
     8101 ggcgatgagg aacggcagcg cgtcataaac gcccggcgca tcttcattgg gtaaacccgc
     8161 tttcatggaa cggtaagtgc ctacgccaac gaagaccgcg tcgtattgtt ccaaaagcga
     8221 attcaaagag acatctttac ccacttcaca attgagttcg aagtgaatcc ccatcgcgct
     8281 gaagatttcc cgacggcgtg ccagcaggga tttatccagt ttgaaagaag gaatgccgaa
     8341 agtgagcaag ccaccgattt ctggatggcg atcgtacacc gtcaccgcca cgccattgcg
     8401 ggtcagaaca tctgcacagg ccagccctgc cggacccgca ccgataatcg ccacccgctt
     8461 gtccactttg gtgacatggc ttaagtcagg acgccaacct ttcgccaacg cctgatctga
     8521 aatgtagcgt tcaatgttac cgatagttac tgcgccgtgc tcatcgcgaa tagtacaggc
     8581 accttcacac aaacggtctt gcgggcaaac gcgtccggta atttccggca gggtgttggt
     8641 ctggtgagaa agctcgacgg cggcgtcgat gtttccggct ttcaccagtt caatccactg
     8701 cggtatatgg ttatgcagcg ggcaggtcca ttcacaaacg ctgtgctcgc cgcacttaag
     8761 gcagcgcgag gcttcccgtt gtgcctgatc ggcacggaat ggcagataaa tttcatcaaa
     8821 accggttttg cgcgcttcaa tcgccagttt atctggctcg ccacgcgcgg gcgttgcctg
     8881 catttgctcg actttactca ttaccggcat ttcttgcgcc gcggtactgg catgccacgg
     8941 ttgatgttcc tgacgtgcgg tgcgcaagcg gcgggatttc gccatgccgg agagtgcggc
     9001 gtcagtgacc agttgcagcg cgtccgccgg gcaattttcg acacaggcag gaccgttttc
     9061 gcgccctgca caaaggtcgc atttatgcgc cgtggctttt acttttcctg ccgcaacggg
     9121 tgtcagaacg atttgcatcg taccaaatgg acaggccacc acgcaggatt tacagccaat
     9181 acacttttgc tgattgacct gaatgctgtc atcaacgtgg ctgattgcgc cattagggca
     9241 gctacgggcg cagggcgcat cttcacaatg gtgacaggtc acggcactac gttgctgctg
     9301 atgtttgata accgtaattc ggggatgaaa atggtgttgg ctcaggacat gttgctcgtc
     9361 attgtgagcc atgacacagg cgatttcaca agcatgacaa cccagacatt gctgactgtt
     9421 ggccataata aaacgattca taacgacctt cttttttggt tgtaaaaacc ttattcttta
     9481 tatgagtgtt gttattaccc gacttacagg ggaatcggca atgttcatgt gcccagaata
     9541 agtaactatt tcgctataaa ctgtggcaga tcaaataatc ccatcactga ctaaattgcg
     9601 tttcagcgaa ctggaagatt aatgattttt tgtggagaag acgcgtgtga ttgttaaacg
     9661 acccgtctcg gccagtctgg cccgggcctt tttttacatt gtgctgctgt cgattctttc
     9721 cacgggtatc gctctgctaa cgctggcgag cagtttacgc gacgctgagg ctatcaatat
     9781 tgccggatcg ctgcgtatgc agagttaccg cctgggctac gacttgcaaa gtggcagtcc
     9841 acaactcaat gcacatcgcc agttatttca gcaggcactg cattcaccgg tattaaccaa
     9901 tctcaacgtc tggtatgtgc cagaggcagt aaaaacccgc tatgcgcatc tgaatgccaa
     9961 ctggctggag atgaataatc ggctcagcaa gggcgacttg ccgtggtatc aggccaatat
    10021 taataattat gttaatcaga tagacctgtt cgtgctggct ttacagcact acgctgaacg
    10081 caaaatgctg ctggtggtgg caatttccct ggctggcggc atcggtattt tcacgctggt
    10141 cttttttact ttgcgccgca tacgccatca ggtggttgcc ccgctgaatc agctggttac
    10201 cgccagtcag cgtattgaac acgggcagtt cgactcgccg ccgctggata ccagcctgcc
    10261 gaatgagctt ggcctgcttg caaaaacctt taaccagatg tcgagcgagc tgcataaatt
    10321 gtaccgttcg ctggaggcgt cagtagaaga aaagacccgc gatctccacg aggccaagcg
    10381 tcgtctggag gtgttgtatc agtgttcgca ggcgctaaac accagccaga ttgatgtgca
    10441 ttgtttccgc catattttgc agattgttcg cgacaatgaa gcggctgaat atctggagtt
    10501 aaatgtcggt gacaactggc ggattagcga agggcagcca aacccggaat tgccgatgca
    10561 gattttaccg gtgacaatgc aagagacggt ttacggagaa ctgcactggc aaaatagtca
    10621 cgtttcatca tcagaaccgc tgcttaacag cgtttcgtcg atgctgggac gcggtttgta
    10681 ctttaatcag gcgcagaagc attttcagca gttattgttg atggaagaac gtgcgaccat
    10741 cgcccgcgaa ttgcacgact cgctggctca ggtactttct tacttacgta tccagttgac
    10801 gttactgaag cgttcgatac cggaagataa cgccaccgca caaagtatca tggccgattt
    10861 ttcccaggcg ttgaatgatg cttatcggca gttacgcgag ctgttgacta ctttccgcct
    10921 gacgctgcag caggcggatc tcccctccgc gttgagggaa atgctggata cgttacaaaa
    10981 tcaaaccagc gccaaactga ccctcgactg ccgtctgcca accctggcgc tggatgcgca
    11041 aatgcaggtg catttgttgc aaattattcg cgaagcggtg ctgaatgcga tgaagcacgc
    11101 caacgccagc gaaatcgccg ttagctgcgt caccgcgccg gatggcaatc acacagtcta
    11161 tattcgcgac aacgggattg gcatcggtga accgaaagaa cccgaaggcc attatggtct
    11221 gaatatcatg cgcgaacgcg cggaaagatt gggtgggacg ctgacttttt cacaaccttc
    11281 cggcggcggc acgttagtga gtattagctt tcgctctgcg gagggtgagg aaagtcagct
    11341 gatgtaatgc ctcttattga ccaaagaata gtggcactta aggttcagta taaaagggca
    11401 tgataattta cattaactcc tttttttctc cacgattggc tcgtaccttg ccgctacagt
    11461 gaagcaagcc aagcctacaa cgatacgcag aaacacgagg tcctctttta atggcgaatt
    11521 tctttattga tcgccccatt tttgcctggg tgctggcaat cctgttgtgt ctgacaggta
    11581 ccctggcgat tttttcattg cccgttgaac aataccccga tctcgcgcca ccgaatgtgc
    11641 gagtgaccgc taactatccc ggcgcatcgg cccagacgct ggaaaacacc gtgacccagg
    11701 ttatcgagca aaatatgacc ggcctcgata atctgatgta tatgtcatct cagagcagcg
    11761 gcaccggtca ggcatctgtc acgttaagtt ttaaagcagg caccgatccg gacgaagccg
    11821 tgcagcaagt acaaaaccag ctgcaatcag ccatgcgaaa gttaccgcag gcggtgcaaa
    11881 atcagggcgt gacggtgcgt aaaaccggcg ataccaacat tctgaccatt gccttcgtct
    11941 ctaccgatgg ttcgatggat aaacaggata ttgccgatta tgttgccagt aatattcagg
    12001 acccgttaag ccgcgtgaat ggcgtcgggg atatcgatgc ctatggttcg caatattcca
    12061 tgcgtatctg gctggacccg gcgaaactca acagtttcca gatgacggct aaagatgtca
    12121 ccgatgccat tgaatcacag aacgcgcaga ttgcggttgg gcaacttggt ggtacgcctt
    12181 ccgtcgataa gcaggcgctc aacgccacca ttaacgccca gtcactgctg caaacaccag
    12241 aacagttccg cgatatcacc ttgcgggtga atcaggacgg ctcagaggta aggctgggcg
    12301 atgtcgccac cgtcgaaatg ggggcggaga aatacgatta tcttagccgc ttcaatggta
    12361 agccagcctc cgggctgggg gtaaaactgg cctccggcgc gaacgaaatg gcgacagcgg
    12421 agctggtgct caatcgtctc gacgagctgg cgcagtattt tccacacgga ctggaataca
    12481 aggtggcgta tgaaaccacc tcttttgtaa aagcctccat tgaagacgtg gtgaaaacgc
    12541 ttctggaagc tatcgccctg gttttcctcg ttatgtatct gttcctgcaa aacttccgcg
    12601 ccacgctgat acccactatc gccgtgccgg tggtgttgat gggaaccttc tcggtgcttt
    12661 atgccttcgg ctatagcgtc aacaccttaa ccatgttcgc gatggtgctg gcgatcggtc
    12721 tgctggtgga tgatgccatc gtggtggtgg aaaacgtcga acgtattatg agtgaggaag
    12781 gactcactcc tcgcgaagcc acacgtaaat cgatggggca gatccagggg gcactggtcg
    12841 ggattgcgat ggtgctttcg gcggtatttg tgccaatggc cttcttcggc ggcaccaccg
    12901 gtgccatcta tcgccagttc tctattacca ttgttgcggc gatggtgctg tcagtactgg
    12961 tagcgatgat cctcactccg gctctgtgtg ccacactact taagccactg aaaaaaggtg
    13021 agcatcacgg gcaaaaaggc ttttttgcct ggtttaacca gatgtttaac cgcaacgccg
    13081 aacgctacga aaaaggggtg gcgaaaattc tccaccgtag cctgcgctgg attgtgattt
    13141 atgtcctgct gcttggcggc atggtgttcc tgttcctgcg tttgccgacg tcgttcttac
    13201 cgctggaaga ccgtggcatg tttactacct cggtacagtt gcccagcggt tcaacccagc
    13261 aacagaccct gaaagtcgtt gagcaaatcg agaaatatta cttcacccat gaaaaagaca
    13321 acatcatgtc ggtgtttgcc accgtgggtt ctggccctgg ggggaacggg caaaacgtgg
    13381 cgcgaatgtt tatccgcctg aaagactgga gcgaacgcga cagtaagacc ggcacctcgt
    13441 ttgccattat cgagcgtgca acgaaggcgt ttaacaagat taaagaagct cgcgttatcg
    13501 ccagcagccc gccagcaatt agcggtcttg gtagttctgc gggttttgat atggagttgc
    13561 aggaccacgc tggagcgggt cacgatgcgc tgatggcagc acgaaaccag ttgctggcgc
    13621 tggcagcgga aaacccggag ctaacccgtg tgcgccataa cggcctcgac gacagtccgc
    13681 agttgcagat tgatatcgac cagcgtaaag ctcaggcgct gggcgttgct atcgacgata
    13741 ttaacgacac actgcaaacc gcctggggtt cgagctatgt gaatgacttt atggatcgcg
    13801 gtcgcgtgaa gaaagtctat gtgcaggcag ctgcgccgta tcgcatgctg ccagatgaca
    13861 tcaatctctg gtatgtccga aataaagatg gcggcatggt gcccttctct gctttcgcga
    13921 cctcacgctg ggagacaggc tcgccgcgtc tggaacgcta taacggttat tctgcggttg
    13981 agattgttgg ggaagccgca ccgggggtca gtaccggtac ggcgatggat attatggaat
    14041 cgttagtgaa gcagttgcca aacggctttg gtctggagtg gacggcgatg tcgtatcagg
    14101 agcggctttc cggcgcgcag gctccggcgc tgtacgccat ttccttgctg gtggtattcc
    14161 tgtgtctggc tgcgctgtat gaaagctggt cggtgccgtt ctcggtaatg ctggtcgtgc
    14221 cgctgggggt tatcggcgcg ctgctggcaa cctggatgcg cgggctggaa aacgatgttt
    14281 acttccaggt gggcctgtta acggtcattg gtttatcggc gaaaaacgcc atcctgatcg
    14341 tcgagtttgc taacgagatg aaccaaaaag gccacgacct gtttgaagcg acgctccacg
    14401 cctgccgtca gcgtttacgc ccgattctga tgacctcgct ggcatttatc ttcggcgtat
    14461 tgccaatggc aaccagcaca ggtgccggtt ccggtggtca gcatgcggtg ggtactggcg
    14521 taatgggcgg gatgatttcg gccactattc tggctattta cttcgtgccg ctgttctttg
    14581 tgctggtgcg ccgccgcttc ccgctgaagc cgcgcccgga ataagcaata aaaaaggcga
    14641 catgccaatg tgtcgccctt ttcaactttc cgattaagaa cctgctcagc gggttcttgc
    14701 tgtttgtact ttgtctcagg aattacttac gaagcataac ttcgataaag tctttccagt
    14761 tccccagttc acgttcaatc ataacaacct ctcttataat tatgggtatt ctacggaaac
    14821 aatataccgt ggtgaagcta atttactcga ttgctgcgat gactacctcc gggggacaaa
    14881 ccttatgtaa atactatggt cctgcggtga tgatttgtat gtgatacacc gcaacatttc
    14941 gagatattca tacggcatct aatactgatt taattctggt taaaatacag acagataaca
    15001 agatgaata
//
LOCUS       DAFGPF010000117        14876 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFGPF010000117 DAFGPF010000000
VERSION     DAFGPF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14876
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.117"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(153..860)
                     /locus_tag="LSX49_004085"
     CDS             complement(153..860)
                     /locus_tag="LSX49_004085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBL7170421.1"
                     /translation="MVIGPFINASAVLLGGVLGALLSQRLPERIRVSMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEICLLEKGVNTAVTKAQNLFRHSRKKPAHESF
                     IQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            1253..3388
                     /gene="speC"
                     /locus_tag="LSX49_004086"
     CDS             1253..3388
                     /gene="speC"
                     /locus_tag="LSX49_004086"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HBL7170422.1"
                     /translation="MKSMNIAASSELVSRLSTHRRVVALADTDFTDVAAVVITAADSR
                     SGILALLKRTGFHLPVFLYSEHVVELPAGVTAVINGNEQQWLELESAACQYEENLLPP
                     FYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVALGIEARKAILARCKLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFCVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDANGMKRLYGYVLK"
     gene            complement(3437..4693)
                     /gene="nupG"
                     /locus_tag="LSX49_004087"
     CDS             complement(3437..4693)
                     /gene="nupG"
                     /locus_tag="LSX49_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupG"
                     /protein_id="HBL7170423.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAVLVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(4895..5974)
                     /gene="mltC"
                     /locus_tag="LSX49_004088"
     CDS             complement(4895..5974)
                     /gene="mltC"
                     /locus_tag="LSX49_004088"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HBL7170424.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            complement(6039..6314)
                     /locus_tag="LSX49_004089"
     CDS             complement(6039..6314)
                     /locus_tag="LSX49_004089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HBL7170425.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK"
     gene            complement(6342..7394)
                     /gene="mutY"
                     /locus_tag="LSX49_004090"
     CDS             complement(6342..7394)
                     /gene="mutY"
                     /locus_tag="LSX49_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBL7170426.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQ
                     VATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIATANNSWSL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEDNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            7555..8274
                     /gene="trmB"
                     /locus_tag="LSX49_004091"
     CDS             7555..8274
                     /gene="trmB"
                     /locus_tag="LSX49_004091"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBL7170427.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            8274..8600
                     /locus_tag="LSX49_004092"
     CDS             8274..8600
                     /locus_tag="LSX49_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HBL7170428.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLGEVRTSEL
                     FDVWWD"
     gene            8623..8763
                     /locus_tag="LSX49_004093"
     CDS             8623..8763
                     /locus_tag="LSX49_004093"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170429.1"
                     /translation="MQNCLMRYAYQAWKDAQSSRPDKAFTPHPAWMTCTLLSIWGQQM
                     LA"
     gene            8784..9503
                     /locus_tag="LSX49_004094"
     CDS             8784..9503
                     /locus_tag="LSX49_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HBL7170430.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            9679..10725
                     /gene="ansB"
                     /locus_tag="LSX49_004095"
     CDS             9679..10725
                     /gene="ansB"
                     /locus_tag="LSX49_004095"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HBL7170431.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKTVF
                     DTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            10842..11849
                     /locus_tag="LSX49_004096"
     CDS             10842..11849
                     /locus_tag="LSX49_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HBL7170432.1"
                     /translation="MKKQWIVGTALLMLMTGNVWADGEPPTENILKDQFKKQYHGILK
                     LDAITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     NQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDEFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVSIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWITLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVI
                     K"
     gene            complement(11905..13206)
                     /locus_tag="LSX49_004097"
     CDS             complement(11905..13206)
                     /locus_tag="LSX49_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708726.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL7170433.1"
                     /translation="MDSYIALTLFGCFFVLVFIGVPISFSIGIATVASMLLMFPWDIA
                     AITVSQRLANGLDNFALLAIPFFIFAGTLMNSGGIAIRLINLAQVMVGRVPGSLGHVN
                     VLANMMFGSISGSAVAAAAAVGGTLNPIQTKEGYDPAFSTAVNVSSCITGLLIPPSNV
                     LIVFSLTAGGVSVASLFMAGYLPGILMGLAVMIVCGIIAKRRGYPLSERATFAQACKA
                     FLDALPSLLLVFIVMGGILGGIFTATEASAIAVVYTFILSVLIYREVKWRDLPKLILE
                     SVVTTSIVLLLIGFSVGMSWAMTNADIPYMISDALMGISDNPLVILLLINIVLLIVGI
                     FMDMTPAVLIFTPIFLPIAQELGMDPVHFGIMMVANLCIGLLTPPVGSALFVGCSISG
                     VKIQHLIKPLLPFYAALLITLMMITYIPQISLFIPQLLGLM"
     gene            complement(13206..13709)
                     /locus_tag="LSX49_004098"
     CDS             complement(13206..13709)
                     /locus_tag="LSX49_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708723.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL7170434.1"
                     /translation="MIFNRLKLAVDRVIAAFSVAVMLALVVCVVWQVFSRYVLNQPST
                     LTDELARFLMIWVGLLGAAYTVGAQRHLSIDLFALALNKRKQLLLSIVINVLILGFAG
                     SVIVTGGLKLIDKTLATSQVSAAMQIPMGYVYIILPLSGLVMMFYALCFINQSIQQLK
                     QPAQEAS"
     gene            complement(13754..14740)
                     /locus_tag="LSX49_004099"
     CDS             complement(13754..14740)
                     /locus_tag="LSX49_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBL7170435.1"
                     /translation="MKMRSFTRSLVCASLLALVSTGVNAAEKVTLKLAHNLERSHVVH
                     QSFEELAKEVKQLSKGNMVIRIYPSSQMGNARETMELLQNGALDMTKGSASDLESFDN
                     IYAIYNLPFLFKDQAHFNKVVFGEVGEEIMDSTKDKGFFALSAYVAGTRSFYAKKPIT
                     KPEDLKGLKIRVQPSPTTIKMIELMGGSPTPISFGEVYTAMQQGVVDGAENNVPSWVQ
                     TRHIEIAKVFSEDEHASIPDFLVISTKTWNKLTPEQQQILETAAKKSEADQQKLWEKI
                     DADTRAQAKAMGGEIVKVDKAPFRAAVQPLFDDFKKDPKQAALLEKFDNAAQ"
BASE COUNT         3922 a         3568 c         3776 g         3610 t
ORIGIN      
        1 acacggggat tttcaatccc ctgctctacc gactgagcta tccgggcaac ggggcgcatt
       61 aaacctgatt cgcctcgtct cgtcaatcaa atttcttcaa tttactgcag actgcacaat
      121 ctatcatcac tttgccgcta atgcacgcat tgtcaggcaa accaggcggt ccaggcggcg
      181 gaaaggggca ttgccagaag gagtgctgga agcatgttga ccaccgggaa cattttaatg
      241 ccacagatgc gtaatccggt tgccagcagc aataaaccgc ctacggcgct gaagtctgcc
      301 atcatcgacg gtgtggtcag cggtaatatc agcgcggcag cccacgccag cgttaactgg
      361 atgatcagta atgggatact aatcaccgat accgcaatac ccagcgagca ggcgaagatc
      421 atcgccgtaa agaaatcaag aaatgacttg gcgattaaaa tactcggatc gccggtcatc
      481 ccttcgttca tcgccccgaa gatcccggtg ccgctggcgc aaaacaggac aataatcgcg
      541 acataattct gaataaaaga ttcatgcgct ggcttcttac gtgagtggcg aaacagattt
      601 tgtgctttgg tgaccgcggt attgacgcct ttttccagca gacaaatttc gccgattaat
      661 gcaccgagta aggttgctaa aaccatcgcc ggaaggttgg cgcatttcac caccagtaaa
      721 ataccaatcc ccagcgatgc cagaccaaaa attgatgtca tggagacgcg gatacgttcc
      781 ggtaagcgtt ggctgagcag tgcgccgaga acgccaccca gtaagactgc actagcgttg
      841 ataaaagggc cgatgaccac aagagttcct gttaactgta ttgtttgatt ttcttattat
      901 gaactttttg ccttgttgat ggcttgtctg gtcgcaaagt cctggcttgc acgctttagc
      961 gaaaggtgcc atgattgcgc gaattttctc ctctctgtac ggagtttgcc cgatgcacgc
     1021 cacctcctta cattctctcg cttatcgccg tttcgcgcga aactcctccc tttttctgct
     1081 catgcggtga agttaacgca cgctcactgc aggacaacag taaaatcaga gcgtttctgc
     1141 ttttactgat gtctggcggt cggagctggt gaccagtttg acccatatct cgtggggcag
     1201 ggtttttcac cttgtccggt attcttactt ccccgaaacg ggttttgcgc ttatgaaatc
     1261 aatgaatatt gccgccagta gtgaactggt atcccgactt tctactcatc gccgcgtggt
     1321 ggcgttggca gatactgatt ttacggacgt cgcggcagtc gtcattaccg ctgcggatag
     1381 tcgcagtggc attcttgcgt tgcttaagcg caccggtttt catctaccgg tgtttttgta
     1441 ttccgaacat gttgttgaat tacctgcggg cgttacggcg gtaatcaacg gcaacgagca
     1501 gcagtggctg gagctggaat ccgcagcctg tcagtatgaa gagaatttgc tgccaccgtt
     1561 ttatgacacg ctgacgcagt acgttgagat gggtaatagc acctttgctt gccctggaca
     1621 tcaacatggt gcgttcttta aaaagcatcc tgccggacgc catttttacg atttctttgg
     1681 cgagaacatc tttcgcgccg atatgtgtaa cgctgacgta aaattgggcg atctgctgat
     1741 tcatgaagga tcggcgaaag atgcgcagaa attcgcagcc aaagtctttc atgccgataa
     1801 aacctatttt gtgctgaacg gcacatcggc agcgaataaa gtggtgacga atgcgctgtt
     1861 aacgcgtggc gatttggtgc tcttcgaccg taacaaccat aagtcgaatc atcacggcgc
     1921 gttgattcag gcgggggcga cgccggtcta tctggaagct tcacgtaacc cgtttggttt
     1981 cattggcggt attgatgcgc actgttttaa tgaagagtat ctgcgccagc aaattcgcga
     2041 cgttgcgcca gaaaaagccg acctgccgcg cccgtttcgc ctggcgatta ttcagctggg
     2101 aacctatgac ggcactgtct ataacgcccg tcaggtgatc gataccgttg ggcatctgtg
     2161 tgattacatt ctgtttgatt ccgcgtgggt cggttacgaa cagtttatcc cgatgatggc
     2221 ggatagctcg ccgctgctgt tagaacttaa cgaaaacgat ccggggatct ttgtgaccca
     2281 gtcggtgcac aaacagcagg cgggattctc acagacgtcg cagatccata aaaaagataa
     2341 ccatatccgt ggacaggcgc gtttttgccc gcataagcgg ttgaataatg cctttatgct
     2401 ccatgcttct accagcccgt tctatccgct gttcgccgcg ctggacgtta acgccaaaat
     2461 tcatgaaggg gagagtgggc gtcggctgtg ggcggagtgc gttgcgttgg ggattgaagc
     2521 ccggaaggcg attcttgcgc gctgtaagct gttccgcccg tttatcccgc ccgttgttga
     2581 tggcaaattg tggcaggatt atccgacgtc agtgttagcc agcgaccgcc gttttttcag
     2641 ttttgagccg ggggcgaagt ggcacggctt tgaaggatat gccgcggatc agtattttgt
     2701 tgatccgtgc aagctgttac tcaccacgcc gggtatcgat gccgaaaccg gcgaatatag
     2761 cgatttttgc gttccagcga cgattctggc gcactacctg cgtgagaacg gcattgtgcc
     2821 ggagaagtgc gatctcaact ccattctgtt cttattaact ccggcggaaa gccacgagaa
     2881 gctggcacaa ctggtggcga tgctggcgca gtttgaacag catattgagg atgactcgcc
     2941 gctggctgag gtgttgccga gcgtttataa caaatatccg gtgcgctatc gcgactacac
     3001 cctgcgtcag ttgtgtcagg agatgcacga tctgtatgtc agtttcgacg tcaaagacct
     3061 acaaaaagcg atgttccgcc agcagagttt cccgtcagtg gtgatgaatc cccaggatgc
     3121 gcatagcgct tatattcgcg gtgaagtgga gttggtgcgg attcgtgatg ccgaagggcg
     3181 aattgcggca gaaggggcgt tgccttatcc acctggcgtg ctttgcgtgg tacccgggga
     3241 agtctggggt ggggcggttc aacgttattt ccttgcgctg gaagaaggcg tgaatttgtt
     3301 gccgggattt tcgccggagt tgcaaggtgt ctatagcgaa accgatgcga atggcatgaa
     3361 acggttgtac ggttatgtgt tgaagtaaga ataaaaaaac gggtcacctt ctggcgaccc
     3421 gtttttcttt gcgtaattag tggctaaccg tctgtgtacc tgtcgggaca cgaacgtgtt
     3481 tatatttgaa catcgccatg aacgcgaagg ccagaaccac ggagtaacct gcgaaaatca
     3541 gccatacggt ctgccagtcg gtaatgccgt tttgggtgta catctcaacc actttaccgc
     3601 tcacgatgcc gccgaggata cagccgaagc cgttggtcat catcaggaac atcccctgcg
     3661 cgctggcgcg aattgccgga ctaacttctt tttcgacaaa caccgaacca gagatgttga
     3721 agaagtcgaa tgcgcaaccg taaacgatca tcgacagtac cagcagtaca gtaccgaacg
     3781 gagtcgggtc gccgtaagca aacagagcaa aacgcaggat ccacgctaca atactgatca
     3841 tcattacgtt cttaataccg tagcggctta agaagaacgg gatggtcaga atgaacaggg
     3901 tttcagagat ctgcgaaatc gacatgatga ttgacgcatg ctgcacgatg aagctgctgg
     3961 caaacatcgg atctttgtcg aagctgtgca ggaaggtatt accgaacatg ttggtaatct
     4021 gcagttccgc gcccagcagc attgagaaga tgaagaagat tgccatacgc ttgtttttaa
     4081 acagcgcgaa tgcatcgagg cccagcaggg ttgtccagct ctgattcgct tgctgtttag
     4141 caaccggaat atgcggcaga gtcagggtaa acagaaccag aacggcggaa agagctgcgc
     4201 caatatacag ctgcatgtgg cttaattcga agccggacag gctcaccacc cacattgcca
     4261 tgataaagcc gatggtgccc cagatacgga ttggcgggaa gtcagtaacg atatccatcc
     4321 cggcattttg caggcgatag taagagatgg tgttgattaa cccaagcgtt ggcatataag
     4381 caaacgagtt aatcaatatc acaaggaaca tcgcctccgg cgtagtgacc tctgccgcca
     4441 tgaacagcgt gatagcgcca atggtgtggc aaatggcata gacccatttc gcacttaacc
     4501 atttgtcggc cacaatcccc agcagcgcag gcataaagac cgcggcgata cccagtgagc
     4561 tataaactgc gccgatagaa gcaccgtcaa acttcagggt aacaaacata taggagccga
     4621 gggtcgtcag ccaacttccc cacagacaga actgcagaaa agagaggatt ttcagctgca
     4681 gcttaagatt catgttaatt tcctcacatc gtgatgcgga tgagtgtttg aaaaagcaca
     4741 tttgaccgtg cgagatgatg cgattctatc aacttcgcgg actggttttt tgttacctgt
     4801 ggcaaataat tgcaaacatt cccaatttgc aaaacgaaat tgtgatgtgg ataacatttt
     4861 tacccctgag catcgtcagg ggcggttagt ggaattatcg gcggcggtaa gatttttgcg
     4921 cggtattcac tttataaaga taacggcgag attccgcaga gggatggcgg gtcgtcagcg
     4981 tctgataaac atcgcccggc gtcatggtgt taataatatt ggcagcctga atcttatcat
     5041 tcgaaaagac tcgtagcacg ctgcctgcgc cgccgttata ggcggtgatg acggcataac
     5101 gccgcgatgt tgggttatca attccgccga gataaacgtt gttcagcatc gccagatacg
     5161 cggtgccggt atcaatattg ctggcaggat caaacaagaa actgcggctc ggcgtgccgg
     5221 atttcccctg cgagcggaac acatctttcc cggcggtatg ttgtaccacc tgcattaatc
     5281 ccagcgcatc ggaacggctg accgcatacg ggttaaagga agattcagtc tgcataattg
     5341 ccagaatcag cgactcatca acgccatatt tgcgtgacgc ctggcggacc ataccgagat
     5401 atttgtgcgc acgtttatca aggtggttcg gcaccatgtt aatggtgacg ctgtagatga
     5461 tacgcagccc gttgctgcgg ctcttcagac ggtttttcag cagataatcc gcgaagttgc
     5521 tcgcgcgacc ttcccagcga atcggctgcc cggtgttgtc caccacctga ccgtaaagga
     5581 aaggttcttt cgaaatcgta atatcatcaa cgtcggaata gagatcgacc gaactcggat
     5641 cgtcccccat cagcaacgtt ttgattattg cccggcgcaa atgcgcggca ggttctgtcc
     5701 cggcgatggt ttcgatagta atcgtaccgt catcgaagtt gatgtggctg cgggtctgat
     5761 attgatcggt gtatttcacg tagtccttag gaccggcgat caccacctct ttgaagcccc
     5821 agatgttctc aatattgtgg gcaaattgcc ccatcagaat atcaaaaccg ttggtatctt
     5881 tgacccaggc ttcgttatag gtatcgcctt ttttggtcgt cgaacaggag atgagcaacg
     5941 gcgcaatcaa agccagcgcg agatattttt tcatcattcc gggtgcgtgt tgtgtttgtt
     6001 tttatgcaag ttgccggagg cgtgctccgg cactgttttt attttttatc ttccggcgta
     6061 tagccctcga tatgcacctc tttaccctcg aacaggaagt tgaccatctc ctgctccagc
     6121 agcttgcggt gctcggcatt catcatgttg agtttctttt cattaatcag catggtttgt
     6181 ttgtgctgcc actgcgccca ggcttctttg gagatctcgt tatagatgcg ttttcccagc
     6241 tcgccggggt acagctgaaa atcctgacct tctgcttcac gttgcaggaa agtacaaaaa
     6301 atcgttctgc tcataaatca tcctctttat cgactcacgc gctaaaccgg cgcgccagtg
     6361 cgtaactgct gtaacaaacg ctccacggga gccgccaggc caactgacgg cggttgcgct
     6421 aagttatacc agagcgcatt gtcttcatcc atgcagccgg tgaatgacga cacgggaagc
     6481 cacataggca caatatctaa gtggaaatgg ctgaaggtat gccgaaacgc ggtcagttgc
     6541 gtcaggttat cggcagcaat ctgccgttgc gccagccact gccgcaaact ttcttcgtcg
     6601 gcaaactgtg ggaaacagta taaaccgccc cacaatccac tcggcgggcg ctgcgccagc
     6661 aatacttcat cttcgtgctg taacagcaga aagtagccgg tgcgctccgg cagcgtctgt
     6721 ttcggttttt tgcccggata aagcgaccag ctattgttgg cggtggcaat acatccgttt
     6781 tgtagcggac agagcgaaca tttcggcttc gagcgcgtac aaatcatcgc gcctaaatcc
     6841 atcatcgcct gattaaaccg ttccacgccg acagcgggcg tcacctgctc gctcaaactc
     6901 cataatttat tctcgacctc ttttttcccg ggccagccgc ttacagcata gcagcgcgcc
     6961 agcacccgtt tgacgttacc gtcgagaatc ggaaagtgct tacccagaga aagcgagaga
     7021 atcgcgcctg cggtggaacg cccgacgccc ggtaacgccg cgacttcttc aaaggtttcc
     7081 gggaatttac cgccgtgtaa ggtcgccact tgctgtgccg ctttatgcag attgcgcgcg
     7141 cgggcgtaat agccaagccc ggtccacaag tggagaactt cgtcgagcgg cgcattggcg
     7201 agatcggtca ccgttgggaa gcgcgccata aagcgttcaa aataggggat aacggtcgca
     7261 acctgagttt gttgcaacat cacttctgag agccatactt tgtagggcgt cttgtcaatt
     7321 tgccagggca gcgttttccg cccgtattta tcgtaccagt ccagaacctg ggctgaaaat
     7381 tgcgacgctt gcatggtcac cgaattcact gttgttgggg gcaagattgc agcacagcga
     7441 cggcagggtg taaaccggaa ctttccgcag ccacggcctt atcatgcttg catccggcaa
     7501 ctaactttgg ataatgcccg ttttcagaac actttcacaa gcgactaaat ctttatgaaa
     7561 aacgacgtca tctcaccgga atttgatgaa aacggccgcc cactgcgccg tatccgtagt
     7621 tttgtgcgcc gccaggggcg actgaccaaa ggccaggaac atgcgctgga aaactactgg
     7681 ccggtgatgg gcgttgagtt cagcgaagat atgctggatt tccctgcgct ttttggccgt
     7741 gaagcgccgg tgacgcttga gattggtttc ggcatggggg cgtcgctggt ggcaatggct
     7801 aaagatcgcc ccgagcagga cttcctcggc attgaagtgc attcaccggg cgttggtgcg
     7861 tgcctggctt ctgcgcatga agagggctta agcaacctgc gcgtgatgtg tcacgatgcg
     7921 gttgaagtgc tgcataaaat gattcctgac aattcattgc gcatggtgca gctctttttc
     7981 cctgacccgt ggcacaaagc gcgccataat aaacgccgta tcgttcaggt gccgtttgcc
     8041 gaactggtaa aaagcaaact gcagctgggg ggcgtattcc atatggcgac cgactgggaa
     8101 ccttatgcgg aacatatgct tgaagtgatg tcttctattg acggttataa aaacctgtca
     8161 gagagcaatg attacgtacc gcgtccggca tcacgtccgg tgacgaaatt tgaacaacgt
     8221 ggtcatcgtc ttggtcacgg agtatgggac ttaatgttcg agagggtgaa ataatggcaa
     8281 agaaccgtag ccgtcgtctg cgtaaaaaaa tgcacatcga cgaattccag gaattaggat
     8341 tttcggtggc atggcgattc ccggaaggta catcggaaga acagattgat aaaaccgttg
     8401 atgactttat taacgaggtt atcgaaccga acaaactggc ctttgacggc agcggttatc
     8461 tggcctggga aggtctgatc tgcatgcagg aaatcggcaa atgcaccgaa gaacatcagg
     8521 cgattgtgcg taagtggctg gaagagcgca aactgggcga ggtacgcacc agcgaacttt
     8581 tcgacgtttg gtgggactaa gaaaacatac gggcgatgac aaatgcaaaa ctgtctgatg
     8641 cgctacgctt atcaggcctg gaaagatgca caatcgagta ggccggataa ggcgtttacg
     8701 ccgcatccgg catggatgac atgtactttg ttatcaatct ggggccagca aatgctggcc
     8761 tgatttgttc ttgagggaag actatgatgc gcaaaatgct gctggcggca gcactttcag
     8821 tgacggcaat gaccgctcac gccgactacc agtgcagcgt cacgccgcgt gacgatgtga
     8881 ttgtcagccc gcaaaccgtg caggtgaagg gcgaaaacgg caatctggtg atcacgccag
     8941 acggcaacgt gatgtataac ggtaagcaat attccctgaa cgccgcccag cgcgagcagg
     9001 cgaaggatta tcaggctgaa ctgcgtagca ccctgccgtg gattgatgaa ggcgcgaaaa
     9061 gccgcgtcga gaaagcccgt attgcgctgg ataaaattat cgttcaggag atgggcgaaa
     9121 gcagcaaaat gcgcagccgt ctgaccaaac ttgatgcgca gctgaaagag cagatgaacc
     9181 gcattatcga aacgcgcagc gatggcctga cgtttcacta taaagccatt gatcaggttc
     9241 gcgccgaagg ccagcaatta gtgaatcagg caatgggcgg aattttacag gacagcatta
     9301 atgaaatggg cgcgaaagcg gtgctgaaaa gcggtggtaa cccattacag aatgtgctgg
     9361 gaagcctggg cggtctgcaa tcctcaatcc aaaccgaatg gaaaaagcag gaaaaagatt
     9421 tccagcagtt tggcaaagat gtttgtagcc gcgttgtgac tctggaagat agtcgcaaag
     9481 ccctggtcgg gaatttaaaa taatcctcta ttttaagacg gcataatact tttttatgcc
     9541 gtttaattct tcgttttgtt acctgcctct aactttgtag atctccaaaa tatattcacg
     9601 ttgtaaattg tttaacgtca aatttcccat acaaagctaa gggataatgc gtagcgttca
     9661 cgtaactgga ggaatgaaat ggagtttttc aaaaagacgg cacttgccgc actggttatg
     9721 ggttttagtg gtgcagcatt ggcattaccc aatatcacca ttttagcaac cggcgggacc
     9781 attgccggtg gtggtgactc cgcaaccaaa tctaactaca cagcgggtaa agttggcgta
     9841 gaaaatctgg ttaatgcggt gccgcaactg aaggacattg cgaacgttaa aggcgagcag
     9901 gtagtgaata tcggctccca ggacatgaac gataatgtct ggctgacact ggcgaaaaaa
     9961 attaacaccg actgcgataa aaccgacggc ttcgtcatta ctcacggtac cgacacgatg
    10021 gaagaaaccg cttacttcct cgacctgacg gtgaaatgcg acaaaccggt ggtgatggtc
    10081 ggtgcaatgc gcccgtccac gtctatgagc gcagacggtc cattcaacct gtataacgcg
    10141 gtagtgaccg cagctgataa agcctccgct aatcgtggcg tactggtggt gatgaacgac
    10201 accgtactgg acggtcgcga tgtcaccaaa accaacacca ccgacgtagc gaccttcaag
    10261 tctgttaact acggtcctct gggttacatt cacaacggta agattgacta ccaacgtacc
    10321 ccggcacgta agcacaccag cgatacgcca ttcgatgtct ctaagctgaa tgagctgccg
    10381 aaagtcggca tcgtttataa ctacgctaac gcatccgatc ttccggctaa agcactggta
    10441 gatgcgggct atgatggcat cgtcagcgct ggtgtgggta acggcaacct gtataaaacc
    10501 gtatttgaca cccttgcaac cgccgcgaaa aacggcactg cagtagtgcg ttcttcccgt
    10561 gtaccgacgg gcgctaccac tcaggatgct gaagtggatg atgcgaaata cggcttcgtc
    10621 gcctctggca cgctgaaccc gcaaaaagcg cgcgtcctgc tgcagctggc tctgacgcaa
    10681 accaaagatc cgcagcagat ccagcagatc ttcaatcagt actaatcacc tcgccccggt
    10741 atcgtgccgg ggctttttca cttcagactt acgtccattg ccaattttca ttaccctgat
    10801 gataatcact ggaataaatt attccgcgcg agggttttcg ggtgaaaaag caatggattg
    10861 ttggcacggc gctgcttatg ttgatgactg gtaatgtctg ggcagatggc gaaccgccaa
    10921 ctgaaaatat cttaaaagat caattcaaaa agcagtatca cggcattctc aagcttgatg
    10981 ctatcacctt aaaaaatctt gatgctaagg gtaatcaggc cacctggtca gcggaaggcg
    11041 atgtctcttc cagtgacgat ctctatacct gggtcggtca gttggcagat tacgaactgc
    11101 tcgaacagac ctggacgaaa gataaaccgg taaaattctc ggcgatgtta accagtaaag
    11161 gaacgcccgc gtctggctgg tcggtgaact tttactcttt tcaggcggca gccagcgatc
    11221 gtgggcgggt ggtcgacgat atcaaaacga ataataaata tctgatcgtg aatagcgaag
    11281 atttcaatta tcgctttagt cagcttgagt ctgcgttgaa taaccagaag aactcgattc
    11341 ctgcgctgga aaaggaagtg aaagcgcttg ataagcaaat ggtggcggcg cagaaagcag
    11401 cggatgcata ttggggaaaa gatgcaaacg gtaagcaaat gacccgcgaa gacgccttta
    11461 aaaaaattca ccaacagcgt gatgagttta ataaacagaa tgatagcgag gcgttcgcgg
    11521 ttaaatatga caaagaggtt tatcaaccgg cgattgcggc atgtcataaa cagagtgaag
    11581 agtgttatga agtgtcgatt cagcagaagc gagatttcga tatcaacgaa caacggcgac
    11641 agacttttct gcaatcacaa aaacttagcc gtaaattgca ggatgactgg ataacgctcg
    11701 agaaagggca atatccgtta acgatgaaag tttcagaaat aaacagtaaa aaagtcgcga
    11761 ttttgatgaa aattgacgat atcaatcagg ctaatgaacg ctggaaaaaa gataccgaac
    11821 aattgcggcg caatggagtg attaagtaac tcatgttaag tacctttgcc ggataatata
    11881 aaaagttatc cggcaaatta ttttttacat tagccctagt agctgtggaa tgaacaagga
    11941 tatttgcggg atgtaagtga tcatcatcaa cgtgattaac aatgcggcat aaaatggcag
    12001 caatggtttg atcaaatgtt gaatcttcac acctgaaata gaacaaccaa caaatagcgc
    12061 actacccacc ggcggtgtta acagcccaat acaaaggttg gccaccatca taataccgaa
    12121 atgtaccgga tccattccca gctcttgtgc aatcggcaag aagattggtg tgaagattag
    12181 tacagccggt gtcatgtcca taaagatgcc gacaattaat aagacgatat taatcagcag
    12241 caatatgacc agtgggttat cagaaatccc catcaacgcg tcgctgatca tataaggaat
    12301 atcagcattg gtcattgccc aggacatgcc cacggaaaaa ccgatcaaca gtaatacaat
    12361 cgaagtggta acaaccgatt ccagaatcag tttgggtaaa tcgcgccatt ttacttcccg
    12421 gtaaatcagc accgagagaa taaatgtgta gacaacggca attgctgacg cttcagttgc
    12481 ggtaaaaatg ccgcccagaa tgccgcccat tacaatgaac accagaagca aacttggtaa
    12541 ggcatccaga aacgctttac atgcctgagc aaaggttgct ctttctgaaa gtgggtagcc
    12601 acggcgttta gcaataatgc cgcagactat cattaccgcg agacccatta agatccctgg
    12661 caaatatccc gccataaata gcgatgctac agaaacgccg ccagctgtca gggaaaacac
    12721 aattaacacg tttgagggcg gtatcagtaa tccagtaata caagatgaga cgtttacagc
    12781 ggtagaaaat gccggatcat aaccttcttt ggtctgaatg ggattcagtg tgccaccaac
    12841 ggcagcagct gccgcaacag ctgaaccaga aatggaacca aacatcatat tcgccaggac
    12901 gttcacatga ccaagcgaac caggaacgcg gccaaccatt acctgggcga ggttaatcaa
    12961 acgtatcgca ataccgccgc tgttcatcag cgttccggca aagatgaaaa aggggattgc
    13021 caatagggca aagttatcca gtccattagc cagtcgctgc gaaacagtga ttgccgcgat
    13081 atcccaggga aacatcaaca gcattgaagc tacagtggca ataccgattg agaacgaaat
    13141 gggcacacca ataaagacca gcacaaaaaa acagccaaac agtgtaagcg cgatataact
    13201 atccattaac tggcctcctg cgcaggttgt ttcagttgtt gaatgctttg attaataaaa
    13261 cacaaggcat aaaacatcat caccaatcca cttaatggca gaatgatata tacgtatccc
    13321 atcggtattt gcatcgcggc agatacctgt gatgttgcca gtgttttatc aattaatttc
    13381 aggccaccag tcacaataac cgaaccggca aaacctaaaa taagaacgtt aatgactata
    13441 ctaagaagta attgcttgcg cttattcagg gcgagagcaa ataaatcgat agagagatgt
    13501 ctctgcgcgc cgacggtata tgcagcacct aataatccta cccagatcat caaaaagcgt
    13561 gccagctcat cggttaatgt acttggctgg ttaagtacgt agcggctaaa tacttgccag
    13621 actacgcata caaccagagc aagcattacg gcgacagaaa acgcggcaat gacgcggtct
    13681 accgcaagtt tcaggcggtt aaatatcatt gtaagcatcc tggaaaatca gggccagaga
    13741 ctggcccgaa atattattga gcagcgttgt cgaatttctc taacaaagca gcttgttttg
    13801 gatctttttt gaagtcgtca aacagaggtt gaactgcggc acggaatggg gctttatcaa
    13861 ccttaacgat ttcaccaccc atagctttcg cctgagcacg tgtgtcagcg tcaatttttt
    13921 cccacaattt ttgttgatca gcttcggatt tcttcgccgc tgtttcgagg atttgttgct
    13981 gttctggggt taatttattc catgttttgg tggagataac caaaaagtca ggaattgagg
    14041 catgttcatc ttcagaaaag actttggcaa tttcgatatg tctagtctgc acccaggaag
    14101 gcacgttatt ttctgcgcca tctactacac cttgctgcat cgcagtataa acttcgccaa
    14161 atgaaattgg agtgggtgag ccacccatca gttcaatcat tttgatggtg gtcgggcttg
    14221 gctgaacacg aattttcagc cctttaagat cttctggctt agtaatcggt tttttcgcat
    14281 agaaactgcg tgtacccgct acataagctg ataaagcaaa aaagccttta tcttttgttg
    14341 aatccataat ttcttcacca acttcaccaa aaaccacttt gttgaagtgc gcctgatctt
    14401 taaataagaa cggcaaatta tagatagcat aaatattatc aaaagactcc agatcactgg
    14461 cggaaccttt ggtcatatcc agtgcaccat tttgcaacaa ctccatagtt tctcgcgcat
    14521 tacccatctg gctgctggga taaatacgga tcaccatatt accttttgac agctgtttta
    14581 cctctttcgc cagctcttca aaactctgat gtacaacatg acttctttcc aggttgtgtg
    14641 ctaactttaa cgtcactttt tctgcggcgt ttacgccagt gctaaccaga gccagcaagg
    14701 atgcgcagac taatgagcgg gtaaatgacc tcattttcat aaaaaaactc cctgttgaag
    14761 aatggaaatt ggttgatatc taattgtgct tatcagtgct ttgtgcgaca aattggttaa
    14821 cctgtctgac aacttgtcta tgtttatcac aacttgaaat aaagtcagaa attaaa
//
LOCUS       DAFGPF010000118        14765 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFGPF010000118 DAFGPF010000000
VERSION     DAFGPF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14765
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.118"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(62..547)
                     /locus_tag="LSX49_004100"
     CDS             complement(62..547)
                     /locus_tag="LSX49_004100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBL7170436.1"
                     /translation="MKTISHNSTTSSVSVTAASGNDQPQLVATIVPDEQRISFWPQHF
                     GLIPQWVALEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNA
                     MNGNRAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRII
                     D"
     gene            complement(602..1420)
                     /locus_tag="LSX49_004101"
     CDS             complement(602..1420)
                     /locus_tag="LSX49_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBL7170437.1"
                     /translation="MRLASRFGYANQIRRDRPLTHEELMHYVPGIFGEDKHTSRSQNY
                     TYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLILPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESLR"
     gene            complement(1521..1754)
                     /locus_tag="LSX49_004102"
     CDS             complement(1521..1754)
                     /locus_tag="LSX49_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001119724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HBL7170438.1"
                     /translation="MLGYTEYVLAEGSFSYGQAVAVITAYRNVFIQDDPGMHFRRVIR
                     NAEGQRRWRCRNSEADAGKQLNAWLASGGLLRQ"
     gene            complement(1833..2288)
                     /locus_tag="LSX49_004103"
     CDS             complement(1833..2288)
                     /locus_tag="LSX49_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170439.1"
                     /translation="MIHLFKTCMITAFILGLTWSAPLRAQDQRYISIRNTDTIWLPGN
                     ICAYQFRLDNGGNDEGFGPLTITLQLKDKYGQTLVTRKMETEAFGDSNATRTTDAFLE
                     TECVENVATTEIIKATEESNGHRVSLPLSVFDPQDYHPLLITVSGKNVN"
     gene            complement(2364..3491)
                     /locus_tag="LSX49_004104"
                     /pseudo
     CDS             complement(2364..3491)
                     /locus_tag="LSX49_004104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708766.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3586..6708)
                     /gene="ag43"
                     /locus_tag="LSX49_004105"
     CDS             complement(3586..6708)
                     /gene="ag43"
                     /locus_tag="LSX49_004105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HBL7170440.1"
                     /translation="MKRHLNTCYRLVWNHITGAFVVASELARARGKRGGVAVALSLAA
                     VTSLPVLAADIVVHPCETVNGGTLVNHDNQFVSGTADGVTVSTGLELGPDSDENTGGQ
                     WIKAGGTGRNTTVTANGRQIVQAGGTASDTVIRDGGGQSLNGLAVNTTLDNRGEQWVH
                     GGGKAAGTIINQDGYQTIKHGGLATGTIVNTGAEGGPESENVSSGQMVGGTAESTTIN
                     KNGRQVIWSSGMARDTLIYAGGDQTVHGEAHNTRLEGGNQYVHNGGTATETLINRDGW
                     QVIKEGGTAAHTTINQKGKLQVNAGGKASDVTQNTGGALVTSTAATVTGTNRLGAFSV
                     VAGKADNVVLENGGRLDVLSGHTATNTRVDDGGTLDIRNGGAATTVSMGNGGVLLADS
                     GAAVSGTRSDGKAFSIGGGQADALMLEKGSSFTLNAGDTATDTTVNGGLFTARGGTLA
                     GTTTLNNGATLTLSGKTVNNDTLTIREGDALLQGGALTGNGSVEKSGSGTLTVSNTTL
                     TQKAVNLNEGTLTLNDSTVTTDVIAQRGTALKLTGSTVLNGAIDPTNVTLTSGATWNI
                     PDNATVQSVVDDLSHAGQIHFTSARTGKFVPTTLQVKNLNGQNGTISLRVRPDMAQNN
                     ADRLVIDGGRATGKTILNLVNAGNSGTGLATTGKGIQVVEAINGATTEEGAFVQGNML
                     QAGAFNYTLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRILAGSRSHQTGVNG
                     ENNSVRLSIQGGHLGHDNNGGIVRGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVY
                     GAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASS
                     DNNDFRARGRGWQGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHG
                     SAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSTKHGVSELPVNWWVQPSVIRTFSSRG
                     DMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARVRENITLGVQAGYAHSVSGNSAEGY
                     NGQATLNVTF"
     gene            complement(7042..7914)
                     /locus_tag="LSX49_004106"
     CDS             complement(7042..7914)
                     /locus_tag="LSX49_004106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HBL7170441.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTRHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVQRFRLSGHGYSMVITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILQCGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWEVDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRAQAREQFTGAVDRIFDTAESVCVASVARTVLRAVRDT
                     VVSVARAVWNWIFF"
     gene            9246..10736
                     /locus_tag="LSX49_004107"
     CDS             9246..10736
                     /locus_tag="LSX49_004107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HBL7170442.1"
                     /translation="MPYFQYPDEFPLSSLPPLIRDAVIEAQQITQAPLGLVAASALGA
                     VSLVCQNLIDVCRLNTLRGPVSLFLLTLAESGERKTAVDKLLMEPLYQQEMLLYSRHK
                     NELTTWKNKEELLKAQKKALLSKLNKELRKGADESETLRQLEALQKNRGEKPVRYKFI
                     FNDATTAAIKNQLCGKWRSVGIMSDEAGIIFDGYTLSELPFINKMWDGSVLSVDRKNE
                     PEQMIENARMTLSLMVQPGLFDRYMERKGSVARDSGFLARCLISKPATTQGKRFINGA
                     VTPGGSLTAFHERLMELARGSIEKSSKDERYCLHFSPEAQKIFIDHYNVLEQDLSPSG
                     PLSQFRGHVSKKTENIARIAALLQYFSQGEGKISADIMTSAVVISSWYTDEYKKLFAL
                     PDESELQLQDARELLDWLIEECRGECPPRVRKNYILQCGPGRFRNRKKLNVLLNILAS
                     QLRLSVVQEGKTTYVLLSEINNITLPELNACYSQKLIRWHEQSFGL"
     gene            complement(10857..11429)
                     /locus_tag="LSX49_004108"
     CDS             complement(10857..11429)
                     /locus_tag="LSX49_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170443.1"
                     /translation="MQKLENRCELLLIQHQKWMTNVTRLIVAHGMGAPHLHGYHRLTL
                     AHFFLPEKGTIISVAPQGLYQVVNPGTPPFIPAIQEGLMTSIQTHEIMLLTHFNLGGV
                     LLSELHRLGENRLANRLNSLLRRFDDRDLYHTLIWLCWYDLMCAHSMQPWTEELKHKS
                     HAELENWAVARKREKRELELMIDEYLLYAC"
     gene            complement(11515..11721)
                     /locus_tag="LSX49_004109"
     CDS             complement(11515..11721)
                     /locus_tag="LSX49_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBL7170444.1"
                     /translation="MNTPVSLMDDQMVDMSFITQLTGLTDKWFYKLIKDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARITQSRP"
     gene            12669..12818
                     /locus_tag="LSX49_004110"
     CDS             12669..12818
                     /locus_tag="LSX49_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
                     /protein_id="HBL7170445.1"
                     /translation="MEKVISHTRYKLTPAELEAFNSAVDHRLAELTMNKLYDRVPASV
                     WKYVT"
     gene            13547..14116
                     /locus_tag="LSX49_004111"
     CDS             13547..14116
                     /locus_tag="LSX49_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HBL7170446.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHSRLTALRVDLRFPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGECKGKKHYHLMLLVN
                     RDTWCRAGDYRAPGSLAGMIKQAWCSALGVDAGRYDTLAHFPVRPAVWLERDDDTGFQ
                     QVLERADYLAKESTKAYGTGERNFGCSRG"
     gene            14283..14666
                     /locus_tag="LSX49_004112"
     CDS             14283..14666
                     /locus_tag="LSX49_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170447.1"
                     /translation="MYAKSFLALDGNGRLTGARTAQTAPYAHYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTEHAQQCPYVRPERREIRLIKRLQQFVPDALPVVRKASWYCRQC
                     HHDYYGEQYCTHCQTGRFSEEGVAE"
BASE COUNT         3442 a         3787 c         3895 g         3641 t
ORIGIN      
        1 gctcgccggg cgtcatttct ccgggcagaa aggaaagctg ctgcattgtc cctgcctcca
       61 ttcagtcgat gatgcgcata atggcgctgc attccggatg ctgcagggcg taatcccgca
      121 gccggtaata atggaccgtc atggcataac actccgtacg acaggcgtga tgactgtacg
      181 tcatcagaca ggcagcaatg ccagcggctt ccgggctcat ttcagcgcgg ttgccgttca
      241 tggcattgaa cagtacccat gtttcgtcat catcgtcatc cggttcgggg gccataaatg
      301 ccccgccgtt gttcagggtg tacagattcc agataccacc gcagtagtct tcgcacagac
      361 ggtccatcca gccgaaaaca cggggctcca gggccaccca ctgtggaatg aggccaaaat
      421 gctgcggcca gaagctgatg cgctgttcat cagggactat ggtggcaacc aactgaggct
      481 ggtcattccc tgatgcagcg gttacggaaa cagaagatgt ggtggaatta tgtgaaatgg
      541 ttttcatgaa atgactcctt aaaggacaaa taaatgcgtg gttttcaggg taatggctga
      601 atcagcgcag gctctccagc agggtttccg ccatcaccca caatgcgcgg ttgagcttaa
      661 tgtcagtgtc aatgctgtga atggcacggg tatggatacg ttttccttta gcgctgcgac
      721 ctgaaattcc gcctttcagc atattctcct gaatggtctg ataagcactc cacaggtcct
      781 taccgtaatc ctcccggcgt cgtggcgtca gaatgtcggc ggtggtgacg ggctgatgtt
      841 cgtcaccata acggtaagtc agtgccgcct gtgccagcgc ctggcgtgcc ggtggcggca
      901 gaatcagcga ctgcatggca tcacgctttt cctcaatccg gtcaaacacg cccactacct
      961 cgtaagcccc ttcaatgact ctgtccacca catttccccg gtgcggaaca cgcacttccc
     1021 ccagagactg accacagacg cacccgttct ggcagacgaa cctgaagtaa cccggcagca
     1081 tctggtagct ggaggtaccg tcatgagagt tgagcagaat aatttcaggg acatgttctc
     1141 cgtttatctc tccggcccgc cgcagacgca gcatgtgttt tgtgtatccc cggcggcccg
     1201 ggtcgcgcac acgggtctgg caggcgaaga atggctgaaa gccttcccgc tgcaggcttt
     1261 ccagtacggt gatggtgggg atgtacgtat agttctggct tcgggacgtg tgtttatctt
     1321 ccccgaaaat ccccggcaca tagtgcatca gttcttcgtg tgtcagcgga cggtcacggc
     1381 gtatctggtt cgcataacca aaacgactgg ctagtcgcat aatttgctcc ttatcggtgg
     1441 ttaagattta ctggtgtaat aaatgaaaaa agccgcgtct cccggagaag acgcggcctg
     1501 atggatgaaa tcaatgaggt ttattgtctg agaagccctc cactggcgag ccacgcatta
     1561 agctgttttc cggcatcagc ttcagagttc cggcagcgcc agcgtcgctg accttccgcg
     1621 ttgcggataa cccgacggaa atgcattccc gggtcatcct ggataaacac attgcggtaa
     1681 gcggttatga cagcaaccgc ctgcccgtat gagaaagatc cttcagccag gacatactct
     1741 gtgtaaccca gcatatctgt tttctcctga taaataaaaa gcctctgcca cgcgttgtga
     1801 cagaggctga agcatgaaac tgacttcagg gatcagttaa cgttttttcc ggaaacggta
     1861 atcagcagtg gatggtagtc ctggggatcg aaaaccgata acggcagact gacacgatgg
     1921 ccgttacttt cttcagttgc tttaatgatt tcggttgtgg cgacattttc cacgcactcc
     1981 gtttccagaa atgcgtctgt ggttcgcgtg gcattactgt caccaaaggc ttccgtttcc
     2041 atttttctgg tcaccagcgt ctgaccatat ttgtctttga gttgcagagt gatggtgagg
     2101 gggccaaatc cttcatcgtt tccgccatta tccagccgga actggtaagc acaaatattt
     2161 cccgggagcc atatcgtatc tgtattgcgt atactgatgt aacgttgatc ctgtgcccgg
     2221 agtggggcag accacgttaa ccccagaatg aaggcggtaa tcatgcaggt tttgaacagg
     2281 tgaatcatgg tatttacctc tctgagtcat gacgatgaca ctgacaaatc aggtgataaa
     2341 acgtaaaagg cgcagaatag ccgttatgcc ggtaactccg ggggtaatgt ttcttccagt
     2401 cggttaacca tattgccgag atgggatgca tcatattcca tgacggggcg ttgcctgatg
     2461 atactgacca ccagtggttt gattaacatg ttggtcgcgg cccgttgttg tataccggcg
     2521 gcgaaaatga tctccagagc attctgatcg ataacacggg ccagattcgc gttcagattt
     2581 tcaatctcat gtccggtcag caggaaactg ccggcaagcc atgtcatctg ctcctgaatc
     2641 attgccagaa ttttgacgcg atcttcttca accagcgctc cggcaatttt tcctgataca
     2701 gcggaggcaa tcattccccc cagaacaccg ccaaccacac gccctgtcag tgcaccaaat
     2761 ggtcccagtg gactgaacaa tatcccgccc gccactgacc cgacagcacc acctgccaca
     2821 caggaagatg ccacggcaag attcctgatg aactgcgcac cggagatccg tccccgcaac
     2881 attttgatca tgtcagggcc ggttgtgaca gctaccagtg ccagagatgt caccagcgaa
     2941 cccttcatca ctttgttcag ggcactgata tttcctgcac cggtcccctt ctgaagcgcc
     3001 tgccggacag tcgggctggc cgtcgaaaaa tcaatatgct tcagcatacc ctgaacaaca
     3061 ctgagccggt gaagttgctg ggttgtgacg tagacagcca gtgtgcgggt gaaggttttt
     3121 cctgcctgga cagcagctgt ctgcagggca gcatcgcgat cgccggtgct gagccagaag
     3181 accgatgccg tcagggcaaa actgatccct ccggccgcca gactgacaac cgacccctcg
     3241 gcaatatcat aagtgaccga ttcgatggtc ccgaaccggg tgatattacg ggcctgggta
     3301 taagtcagat gtccccgacg aatcagccgg gacgcttctg cgggatcggt tacaccgggt
     3361 actttacctt cgcggatctt attcttcatg gtttccacag cgccggcata ctgatcacgg
     3421 gggacttcca gttgcatggg accatgattt cccatgtaac gatactgtcc gttctgtccg
     3481 tcgaatgccg cactgttaat gccagcgaat gtggcgttga atatccgttg cgccggtccg
     3541 ggtcccgatc atgatgatcg ggaccacaaa gaggcgatgg ttctgtcaga aggtcacatt
     3601 cagcgtggcc tgaccgttat agccttcagc gctgttgccg ctgacactgt gggcataacc
     3661 ggcctgaacg cccagggtga tattttcccg gacacgggct tccagtccgg cctgcaggtc
     3721 cagtgacgtg ccattccggg acggtgagaa cgtcatgtta ctgccggctg cggctgtacc
     3781 catgctcatg tctccccggg agctgaaggt gcggataaca gaaggctgta cccaccagtt
     3841 cacaggcagt tcactcacac cgtgttttgt actgtcgcgc agggtgtcac gggatgaggt
     3901 gccttcacca aaggtcatat cgttgtggct gcccagacgg aaaccggcac gcacatgttg
     3961 tgcactgcca tgcccgaact tcacataacc ggcgttatcc tggccgtcat ccagggaaag
     4021 tccctgccag gtatactgca gttgtggctc cagcatcagg ttgtcagtga tactgaatgg
     4081 cagaccggtt tccagtgagc cctgccagcc ccggccccgg gcgcggaagt cgttattgtc
     4141 cgatgacgct ttcatgctgt ggcgggttcc ctgtgccaca atgtcagccc acaggccgga
     4201 ggacgtgtgt accagattca ggtatccgcc caggctgccg gcatcatccc ggaccgtgcc
     4261 ggcacgggag ccgtcatcat ccttaacatc aacggaagaa tggcctgcag caccatacac
     4321 tcctgtcgtc agtgacatac cggcaacctc tgttctgagc aggtcaccct ccagacggac
     4381 gaagccatag ctgccgctgc tttccggcgt ggcaccacgg acaataccgc cgttgttatc
     4441 gtgaccgaga tggccgccct gaatgctgag acggacgctg ttattttcac cgtttacacc
     4501 ggtctgatgg ctgcgggagc ctgccagaat ccggtcatag tccattgcct gtgtcagcat
     4561 ggaggcatac agggggactt cagcacgata agcattttca ctgcgcagat accagctctc
     4621 atcactgtcc cggttgaggg tgtagttaaa ggccccggcc tgcaacatat tcccctggac
     4681 aaaagcccct tcctccgtgg tggcaccgtt aatggcctca accacctgaa tacccttacc
     4741 ggtggtcgcc agccccgtac cactgttgcc ggcgttcacc agattcagga tggtttttcc
     4801 ggttgccctg ccaccgtcaa tgaccagtct gtcagcattg ttctgcgcca tatccgggcg
     4861 tacacgcagg ctgatggtgc cattctgccc gttcaggttt ttcacctgca gagttgtcgg
     4921 aacgaacttc cctgtgcggg cggaggtgaa atgaatctgt ccggcatggc tgaggtcatc
     4981 caccaccgac tgaaccgtgg cgttatcggg gatattccag gtggcaccgg atgtcagggt
     5041 gacattcgtg gggtcaatgg caccgttcag cactgtgctg ccggtcagct tcagggctgt
     5101 accgcgctga gcaatgacat ccgtggtgac ggtactgtcg ttcagcgtca gcgtgccttc
     5161 attcaggttg acggctttct gggtgagtgt ggtgttgctg acagtgagtg tgccacttcc
     5221 tgatttttcc acgctgccgt taccggtaag agcgcctccc tgcaggagtg catcgccttc
     5281 acggatggtc agggtatcgt tgttcaccgt cttcccggaa agggtaagtg tggcgccgtt
     5341 attcagcgtg gtggtgcccg ccagtgtgcc gcccctggcg gtgaacagtc cgccatttac
     5401 cgtggtatcc gtggccgtat caccggcgtt cagcgtgaat gaactgcctt tttccagcat
     5461 cagggcatcc gcctgaccgc ctccgatact gaatgccttt ccgtcgctcc gggtaccact
     5521 gacagcggca ccggaatcgg ccagcagtac accgccattc cccatggata cggtggtggc
     5581 ggcaccaccg ttgcggatat ccagcgttcc gccatcatcc acacgggtat tagtggctgt
     5641 gtgtccgctc agcacatcca gacgtccgcc attttccagt acgacattat cagccttacc
     5701 cgccacaacg gagaatgctc ccaggcggtt tgtgccggtg acggttgcag ctgtactggt
     5761 aaccagtgca ccgcccgtgt tctgggtgac atcagacgct ttaccgccgg cattcacctg
     5821 cagctttcct ttctggttga tggtggtatg cgcggcagtt cctccttcct taatcacctg
     5881 ccagccatca cggtttatca gcgtctctgt tgccgtgcca ccgttgtgta catactggtt
     5941 acccccctcc agtcgggtgt tatgtgcctc tccgtgtacc gtctggtcac caccggcgta
     6001 aatgagggtg tcccgtgcca tccccgaaga ccagataacc tgccggccat ttttattgat
     6061 ggtggtggat tcagccgtcc ctccgaccat ctgaccgctg gacacatttt cagactccgg
     6121 accaccttct gcaccggtgt tgacgatggt tccggttgcc agtccgccat gttttatggt
     6181 ctggtaacca tcctggttaa taattgtacc ggcagctttc cctcccccgt gtacccactg
     6241 ctcacctctg ttatccagcg tggtgttcac cgccagtccg ttaaggctct gccctccgcc
     6301 atcacgaata accgtatcac tggcagttcc tcctgcctgc acaatctgac gaccatttgc
     6361 ggtgacagtg gtgtttctgc ctgtgccacc cgcttttatc cattgcccgc cggtgttttc
     6421 gtcactgtcc ggccccagct caagcccggt actgacagtc acgccatcag ctgttccgga
     6481 tacaaactgg ttgtcatggt ttaccagtgt tccgccattc actgtttcac acgggtgcac
     6541 aacgatgtca gcagccagca ccgggagtga cgtgaccgcg gcaagagaca gtgccaccgc
     6601 cacaccgcca cgtttacccc gtgcgcgggc cagttcggag gcaaccacga aagcgcccgt
     6661 aatgtgattc cataccagcc tgtagcaggt attcagatgt cgtttcatca gcatttcctt
     6721 aatcagagtg agggtgaata aaaaagccgg tatccacaga tgtggatacc ggcaggtaaa
     6781 gggttacagt gccggaggtc cggctgacgg aagtttctga cgtgtggctc tgttgttccc
     6841 tgaatctcat gtctgtgtgt atctgcgcac gttgctaaca ggagttatta ttagcataac
     6901 gatcgatatt aacgatcggt aaaatgggta ttgatcgttt tattctttta tcaagctatt
     6961 gcacggacaa gagagacagt aacgaaaaca gcgcttttgt gagcatactt agaggcaggg
     7021 aggacatcat ccacaacagg ttcagaagaa gatccagttc cataccgcgc gggcaacaga
     7081 gaccactgtg tcacggacgg cacgcagaac cgtgcgtgca acagaggcaa cacagacgct
     7141 ctccgctgtg tcaaatatcc ggtccaccgc accggtaaac tgctcacggg cctgagcgcg
     7201 gacagattcc gtgcgcagct cgtcctgcag gcgggtcatc aggggactgg cggcatggtc
     7261 gggaagcgct gtcatgagcg cactgaccag cgtatccact tcccagccgg tgcgggccga
     7321 tacggccaca accggatgta caggccggaa cagacggaat accgcctccg ttttttcgcg
     7381 aatgttctgt gcctgtgcgg gagagggctg aatgccggcc atatcccatt catggcaggg
     7441 ctccgttttg tcggcctgtg tcaccacaaa cagcacctgc tgatgtccgc actgcaggat
     7501 gtgtcgccag aaatactcat ccacagacag ggcccggtca tcggctttaa tcagccacag
     7561 caccaggtcc agttcaggca gaatgtcacg gtacagggct tcatactctg catccctgtc
     7621 ccggctctcg cccaccccgg gcaggtcagt gataaccatg ctgtaaccgt gaccactcag
     7681 acggaagcgc tgcacttccc gggtgccggc gtgaacatca ctgaccggtg tgacctcccc
     7741 ctgaaacagg gcattacaga gtgaagattt accggccccg cttttaccca taatgccaat
     7801 cacgggctcg tgacgggtga gtttgcgcag atgttccagg atgtgacggg aaagcgagta
     7861 aggcagggag gagagcggtt tttcaattgc ctcaatggca tcagacggat tcatacatgt
     7921 attcccggtg aaaaaagaca aaaccccgca caccggaaag gtggcggggg atccacggag
     7981 ataatatctg tctgaaattg tttggaatcg atggggatgt tgcgtattaa catgaaggag
     8041 ggcaggagtt atccgttatt gggtgatatc cttccatgaa aatacgcggt tattgttaaa
     8101 cagcaggctg attactccgt aaaggagaaa aatattcatc ttgcagcctg attatcaggt
     8161 gtgtttatgt ttactgaggt gagtattttt cagtatattg tcggggcagt cagtgggaga
     8221 tattaaattt acgtttagag ttatcttgct tctgctgtgt atttttataa gagtgcgcac
     8281 gtaatgatat ctgttgatac catgttgtta agtgtttccc ttccgggtca tgcgtacttg
     8341 caaaatggca tctgaatcga tcacggtttg gccaaaccgt gatcgaatag ataggaatac
     8401 gcacgtaatg attaaatgct tttgttacac cattcttccg gcatgaatat ttatccagtt
     8461 ccctttttta tttgtgtagt gatactgtcg gaatagcgtt cagtaatgtg aagtgtcctg
     8521 taaaaaaact ttaataaatg tgtcatcctg gtcaggaaat atctgctgag atattattag
     8581 ttggtggtgt ttttactgag taatagctgg cttttaattc ctgaactgaa atactgtcgc
     8641 tcgtcagggt ttaattaaaa ctggatgatg atgtgaaaat gaaggctggt ttttgtgttt
     8701 gtcgaagaag tgttatttta atccattctc atcattggct ggcgattata cagaagtatt
     8761 tgaagaaaaa atgttgcatt ttatctgtgt cagcagggag gaagtatttt attgatgtat
     8821 cagtattaaa tggtttttgt tatttataaa aatgtcatcc tgtccataga atattgtact
     8881 cagcattcag tgcaggaact gtcattttct ttattttatt cttcttcagg agggcagttt
     8941 tctgaaagcg ttactccggg gaaactgttt atgtttattc ccggcaggaa acccgtacct
     9001 gcaataccct ggatgatgct ttttgctggt acgttgttgt gtgaaattta atcaacgtgt
     9061 gtgttccgga gagcgcccgt agacgcacag attcattctg acattcttta gcgacaaaat
     9121 accgaatggt tattatttaa tctgaaaatc gacagaaatt tttatcctgt attgattctg
     9181 ctgctatttt tgctattagt agcaatagtt gcggtacttt atgttctgtg tgttgtgagg
     9241 tcattatgcc atactttcag tatcctgatg agtttcccct gagctcgctg cctccactca
     9301 ttcgtgatgc cgttattgaa gctcagcaaa tcacgcaggc tcccctgggg cttgtggcag
     9361 catctgccct gggcgctgtt tcacttgtct gccagaatct gattgatgtc tgcagactga
     9421 atacactacg ggggccggtt tctcttttct tactgacgct tgctgagtcc ggagaacgaa
     9481 aaaccgcagt ggacaaatta ttaatggagc ccctgtacca gcaggagatg ctgttatatt
     9541 ccagacacaa aaatgaactg acgacatgga aaaataagga agagctttta aaggcgcaga
     9601 aaaaagcatt gttgtcaaaa ctgaataaag aactccgcaa aggcgcggat gagtcagaaa
     9661 cgctcagaca actggaagcg cttcagaaaa acagagggga aaaacctgta agatataaat
     9721 tcatttttaa tgatgccacg actgcggcaa ttaagaatca gctttgtggt aaatggcgtt
     9781 cagtgggtat tatgtcagat gaagccggta taatatttga tgggtatacc ctgtctgagc
     9841 tgccttttat taacaaaatg tgggatggct ccgtattgtc ggtggacaga aagaatgaac
     9901 ccgaacagat gattgaaaat gccagaatga cattatccct catggtacaa cccggtcttt
     9961 ttgaccgata tatggagcga aaaggttctg ttgccaggga cagtggtttt cttgcccgtt
    10021 gtctaatcag taaacctgcc accacgcagg ggaaacgctt tattaacgga gctgtgaccc
    10081 cgggaggatc attaacggca tttcatgaac gattaatgga gctggccaga ggcagtattg
    10141 aaaaatccag taaggatgaa cgttattgtc tgcatttttc tcctgaagcg caaaaaatat
    10201 ttattgatca ctataatgtt ctggagcagg atttgtctcc ttccggaccc ttaagccagt
    10261 ttcggggaca tgtttcaaaa aaaacagaaa acattgcgag aattgctgcg ttattgcagt
    10321 atttcagtca gggtgaaggg aaaatctctg ccgatatcat gacgtctgct gtcgtaataa
    10381 gttcgtggta cacagatgaa tataaaaaat tatttgcgtt acctgatgaa tctgaactgc
    10441 agctgcagga cgcccgggag ctgctcgact ggctcattga ggagtgccgc ggagaatgcc
    10501 cgccccgtgt caggaaaaat tatattctcc agtgtggccc gggccggttc cggaacagga
    10561 aaaagctgaa cgtcctgctg aacattcttg catctcaact caggctctct gtcgtgcagg
    10621 aaggaaaaac cacctatgtc ctgctttccg aaataaacaa tatcacgctg cctgaactga
    10681 atgcgtgcta cagccagaaa ctgataagat ggcatgagca atcctttggc ttataatgtt
    10741 ccctgttgct gagacggatt attcagtggt ggtatcgcag tatgcccgtc acccccgctt
    10801 ctgcatgagg gtgacggagg aaaagtaagt gtgcggaggc ccgggagcgt tatgaatcaa
    10861 caggcgtata acaggtactc gtcaatcatc agttccagct cgcgcttttc ccgtttgcgc
    10921 gccacagccc agttttcaag ctctgcatgt gatttatgct ttaactcttc agtccagggc
    10981 tgcatggagt gggcacacat cagatcatac cagcacagcc atatcagcgt gtggtagaga
    11041 tcacgatcgt cgaaacgccg gagcaggctg ttcagcctgt ttgccagccg gttttcaccc
    11101 agacgatgta gctcactgag taaaacgccg cccagattaa aatgtgtaag cagcatgatt
    11161 tcatgggtct gaatgctggt cattaaccct tcctgaatgg caggaatgaa cggtggtgtt
    11221 cccgggttga cgacctgata gagtccctgt ggtgccactg agatgatggt gcctttttct
    11281 ggcagaaaaa agtgggccag ggtcaggcgg tgataaccat gaagatgcgg agcccccatt
    11341 ccatgagcga cgataagcct cgtcacgttt gtcatccatt tctgatgctg gatgagcagc
    11401 agctcacacc ggttttcaag tttttgcata atattctctc ctttagcgcg cagcaaaatg
    11461 cctccggggg ccggatcatg cctttgctgc ggttgaacgg ataacggtca ggaattacgg
    11521 acgggactgt gtaatacgtg cctgcaacca ggcttccact tcacttttca gccatcggga
    11581 gctacggccc agtttgatgg gggcaggaaa ggcaccatcc ttgatgagct tgtaaaacca
    11641 tttatcggtc aggccggtca gctgagtgat aaacgacatg tcgaccatct ggtcatccat
    11701 cagtgaaact ggggtattca tgaaaatgtt cctccggatg ttgttaatct caaccggcgt
    11761 tggtgatgaa aacaacgcac caccttcccc ggcataacaa ccggggaaaa acgtaaaaaa
    11821 taatcgggaa tgtgaccgtc aggagataaa cggggggatt gcggtggctg agccgtaccg
    11881 gtatgtcggg tgattgttgc gaaacgatgc ttccgcacgc gcacgtgata aaggagggag
    11941 gactttcgtg agacaagggg aaaactggcg ttctgataat tgcagagttg tttttgaagg
    12001 cggttgtggt gcatcagccc gtgacctgtg ggcaggcgac aggtatcact ggtgggataa
    12061 gactgtctga ttggtattat aaatatataa gagagctcaa acacatgagt tcatatatgt
    12121 gaaataaatc tgtgagtgtg atcagcagac cagtctaccc agtagcaaca gattgcgttg
    12181 tactcacagg gttatccctg ataactggcg tataacctgc gtacataaaa cgtacctgca
    12241 atgcacctga acagagtgca ttaagcatcc gcctgagcgg taaacgtatc cgatctggtg
    12301 agtgacagtc tgagagcatt ctcagtaatc gcccccttgt atcctggaaa ttggttaaga
    12361 taacagcgat tagatttggc aaggtgtatg cagccagcag cttaacatct cagctaactg
    12421 gctggttacc ttcaggttgt cgcaatggca tcggacatcc ggtgtcggat aactaaacgt
    12481 agcgttaagg cgatattgct gagagaccgg ttaagtggtt gcacgggagt aatgagtttg
    12541 gggagggtac cagaatgtca gtctggtgcg gtatgctggc agtatcacgt tgattacagc
    12601 ataaagtaac gagagacgaa tggaagttaa aaccagagca gttccgtcgt tgttcatccc
    12661 gggagacgct ggaaaaagtg atttcccaca cacgttataa acttacccct gcggagctgg
    12721 aagcctttaa ctctgcggtc gatcaccggc tggcagaact gacaatgaac aaactttacg
    12781 atcgcgtgcc ggcttccgtc tggaaatatg tcacctgaat cttgaatccg cgctacgatg
    12841 actccggtgt tatctgtgca ccggaagatc gggaacatta agcagtataa cggcaacaaa
    12901 gaattcgaaa tcaaaaggga atggtgtaca gaggggcagg cgttcaggca ttaccggcct
    12961 gtatcttctg aaggggactc gtatttgtcg gggctgagta ttccgctcga ttcgatcacg
    13021 gattggcgga atacctgact gtgattgatt caggtaccat tttgcaggga gccggtgcgt
    13081 tactgtctgg cacaacaaac gcagcgggtc gctctgcccc gccgattcct gataatccct
    13141 cctctgtaac ctactgcaac agtacaaata cactgacgcc tgaaacggta accagaatca
    13201 gcaccagcag taacgtcagt aaacagagca gacgatcggt cttccggtaa taaccgaagg
    13261 ggtcgacagc gccacaatac gggcaacata ctgtattatg agtaattgcg ttaccacagt
    13321 ccctgcactt ctttttgcgt atcacgatcg ctccctctcc acgccttatc cgtaacctgt
    13381 tttttacatt aaaaaaacaa cgccgggaat tcaatcgtca gtccggcgat gaccgttcgg
    13441 gttatcacag agtgcctgag acagtgtcct gccggaggtc acctcagggg ctctgcgcat
    13501 tttttacgac gtggttattc cgtatgaacc atacggagat ttaaccatga cctacaaata
    13561 caaccccttc tggcagcaac gtattcgtga gacggtgcgg cacgcactga atgttcattc
    13621 ccgcctgacg gcattgcggg ttgacctgcg tttcccggat gtaccggcag caacggacgc
    13681 agctgtgata tcccgcttca tcaatgccct gaaagcccga atcgacgctt accagaaacg
    13741 taagcatcgg gaaggtaaac gcgtgcatcc cacaaccctg cattacgtct gggcccggga
    13801 gtttggggag tgcaaaggta aaaaacacta tcacctgatg ctgctggtca accgggatac
    13861 ctggtgtcgt gccggcgatt accgcgctcc gggatcactg gccgggatga ttaaacaggc
    13921 gtggtgcagt gccctgggag tggatgccgg acgttatgac acgctggcac attttccggt
    13981 caggccggcg gtgtggctgg aacgcgatga tgacaccggc tttcagcagg tgctggagcg
    14041 tgctgactat ctggcgaagg agagtaccaa agcttacggc accggtgagc gcaactttgg
    14101 ctgcagtcgt ggctgagccc gacagacgac ttatctgacc ttagtgtgat gacgtgttca
    14161 cagcgaccac actgattttc ccttctgaga ctgaactgaa aaccgccatt cacacctgac
    14221 cacgctgccc gtaccgggac ggctgttgcc tgtgtgtcgt ctggcgcaga ggaacatata
    14281 ctatgtacgc aaaatctttt ctcgcacttg atggcaacgg acgtctgacc ggtgcccgta
    14341 ccgcacaaac tgctccttat gcccactaca cctgccacct ttgcggcagt gcactcagat
    14401 accacccgca atacgacacc gaacggccct ggtttgaaca cactgacgac gggctgacgg
    14461 agcacgcgca gcaatgtcct tatgtcaggc cggaacgcag agaaatacgg ttgattaaac
    14521 gtctgcagca attcgtcccg gatgccttac ccgtggtacg taaagccagc tggtactgca
    14581 ggcaatgtca ccacgattat tatggggagc agtactgcac acactgccag accgggcgtt
    14641 tcagtgagga gggggtagca gaatgaacgg tataaaaacg gggctgggga tcacgccggg
    14701 tgagcacatt atcagtgccg actctgcgct cagcagaaat atccggcatt gtttctgcct
    14761 ttcct
//
LOCUS       DAFGPF010000119        14597 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFGPF010000119 DAFGPF010000000
VERSION     DAFGPF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.119"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1100
                     /gene="ycjT"
                     /locus_tag="LSX49_004113"
     CDS             <1..1100
                     /gene="ycjT"
                     /locus_tag="LSX49_004113"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HBL7170448.1"
                     /translation="TPEFAAINIRTGLRQKVASAQAEHHLVADIAWAVIQYWRTTGDE
                     SFIAHEGMALLLETAKFWISRAVRVNERLEIHDVIGPDEYTEHVNNNAFTSYMAYYNV
                     QQALNIARQFGCSDDAFIHRAEMYLKELRLPEIQPDGVLPQDDSFMAKPVINLAKYKA
                     AAGKQTILLDYSRAEVNEMQILKQADVVMLNYMLPEQFSAASCLANLQFYEPRTIHDS
                     SLSKAIHGIVAARCGLLTQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQG
                     FAGVSVRDGELHLNPALPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNG
                     QLIYVAEESVFCLGDFILPFNGTATTHQEGE"
     gene            1097..1756
                     /gene="pgmB"
                     /locus_tag="LSX49_004114"
     CDS             1097..1756
                     /gene="pgmB"
                     /locus_tag="LSX49_004114"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL7170449.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNEFL
                     KGISRDESLRRILQHGGKEGDFNPQERAQLAYRKNLLYVHSLRELTVNAVLPGIHNLL
                     VDLRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQN
                     V"
     gene            1770..2852
                     /locus_tag="LSX49_004115"
     CDS             1770..2852
                     /locus_tag="LSX49_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7170450.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFSLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGELLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     IQKIAKEMIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVAGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIC"
     gene            2897..3802
                     /gene="ompG"
                     /locus_tag="LSX49_004116"
     CDS             2897..3802
                     /gene="ompG"
                     /locus_tag="LSX49_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HBL7170451.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEEKNNWHFNIGAMYEIENVEGYV
                     EDMDGLAEPSVYFNAANGPWRISLAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLESD
                     DFSLGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(3853..4851)
                     /locus_tag="LSX49_004117"
     CDS             complement(3853..4851)
                     /locus_tag="LSX49_004117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL7170452.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYEIPVVVIGKVEGQYSHV
                     YSVDTDNYGDSIALTNALIESGHKNIACLHAPLDVQVSVDRVNGYKQSLATHNIAVRD
                     EWIVDGGYTHETALKAARELLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDVPTQELGQQSCELLFQLIAGKPSPQNITVATHMSLK"
     gene            5007..6404
                     /locus_tag="LSX49_004118"
     CDS             5007..6404
                     /locus_tag="LSX49_004118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HBL7170453.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSAKWRMMCEGLDPLAPADENRLADIAAAWTEYLHHCKQQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDAWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGMIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            6401..7462
                     /locus_tag="LSX49_004119"
     CDS             6401..7462
                     /locus_tag="LSX49_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HBL7170454.1"
                     /translation="MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDE
                     AQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            7610..9151
                     /gene="tyrR"
                     /locus_tag="LSX49_004120"
     CDS             7610..9151
                     /gene="tyrR"
                     /locus_tag="LSX49_004120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HBL7170455.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRASKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGVFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(9195..9701)
                     /gene="tpx"
                     /locus_tag="LSX49_004121"
     CDS             complement(9195..9701)
                     /gene="tpx"
                     /locus_tag="LSX49_004121"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HBL7170456.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            9820..10785
                     /gene="ycjG"
                     /locus_tag="LSX49_004122"
     CDS             9820..10785
                     /gene="ycjG"
                     /locus_tag="LSX49_004122"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HBL7170457.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGE
                     CTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARK
                     QQQSLADLIGITLPETVTTAQTIVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFRLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            complement(10760..11488)
                     /gene="mpaA"
                     /locus_tag="LSX49_004123"
     CDS             complement(10760..11488)
                     /gene="mpaA"
                     /locus_tag="LSX49_004123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HBL7170458.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASHESGLI
                     LAGTHGDENSSIVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPS"
     gene            complement(11779..12417)
                     /locus_tag="LSX49_004124"
     CDS             complement(11779..12417)
                     /locus_tag="LSX49_004124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707232.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7170459.1"
                     /translation="MKNVLILGAGGQIARHVINQLADKQTIKQTLFARQPAKIHKPYP
                     TNSKIIMGDVLNHAALKQAMQGQDVVYANLTGEDLDIQANSVIAAMKACDVKRLIFVL
                     SLGIYDEVPGKFGEWNNAVIGEPLKPFRRAADAIEASGLEYTILRPAWLTDEDIIDYE
                     LTSRNEPFKGTIVSRKSVAALITDIIDKPEKHIGENIGINQPGTDGDKPFFM"
     gene            complement(12488..13408)
                     /locus_tag="LSX49_004125"
     CDS             complement(12488..13408)
                     /locus_tag="LSX49_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7170460.1"
                     /translation="MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYPAIVVSHPGG
                     GVKEQTAGTYAEKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDVSAVIDYLTT
                     LSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSMFRNGWENNVKSID
                     ALPYVDAGSNARTSDISSGEYATMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPG
                     YATLRSLNQIITYDAYHMAEVYLTQPIQIVAGSLAGSKWMSDDLYDRASSQDKRYHIV
                     EGANHMDLYDGKVYVAEVISVLAPFFEETL"
     gene            13546..14445
                     /gene="pgrR"
                     /locus_tag="LSX49_004126"
     CDS             13546..14445
                     /gene="pgrR"
                     /locus_tag="LSX49_004126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator PgrR"
                     /protein_id="HBL7170461.1"
                     /translation="MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEE
                     RLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDSALTSLSDLQNRPSGTIRITTVE
                     HAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
                     GPDIPMAIVGSPDYFSRRSAPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVR
                     MEGQLLLNTIDLIIDAAIDGHGLAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYY
                     PHRRHAGSAFSLFIDRLKYKGAV"
BASE COUNT         3532 a         3435 c         3909 g         3721 t
ORIGIN      
        1 agacgccgga atttgccgcc attaacattc gtaccgggct gcggcaaaaa gtggcctctg
       61 cgcaggcgga acaccatctg gtcgccgata tcgcctgggc ggtgattcaa tactggcgga
      121 ccacggggga tgaaagtttc attgctcatg aaggcatggc gctacttctg gagacggcaa
      181 agttctggat tagccgcgcg gtgagggtta acgagcgtct ggaaattcat gatgttattg
      241 ggccagacga atataccgaa catgtcaata ataacgcctt caccagctat atggcgtatt
      301 acaacgtcca gcaggcgctg aatatcgctc gtcagtttgg ctgtagcgac gacgcgttta
      361 ttcatcgtgc agaaatgtac ctcaaagaac tgcggctgcc agaaattcag cccgacggcg
      421 ttttgccgca ggatgattcg tttatggcta agccggtgat taatctggcg aaatacaaag
      481 cggcggcggg gaagcaaacc attctgctgg attattcacg cgcagaagtg aacgagatgc
      541 agatcctcaa acaagctgat gtggtgatgc tcaattacat gctgccggag cagttctcag
      601 cggcatcgtg tcttgccaat ctgcaatttt atgaaccgcg cactattcac gactcgtcat
      661 taagtaaagc aatccacggc attgttgccg cacgctgtgg cctgctgacc caaagttatc
      721 agttctggcg cgaggggact gaaatcgatc ttggtgctga tccgcatagc tgtgatgacg
      781 gtatccacgc tgccgcaact ggcgctatct ggctgggggc gattcagggt tttgccgggg
      841 tgagcgtgcg tgacggtgaa ttacatctca atccggcgtt acctgagcag tggcaacagt
      901 tgtctttccc tctgttctgg cagggctgcg aattacaggt cactctcgac gcgcagcgta
      961 ttgcgattcg aacttctgcg cctgtttcac tgcgtttgaa cggtcagctt atttacgtcg
     1021 ctgaagaatc tgttttctgt ttgggggatt ttattttgcc cttcaatggg accgctacca
     1081 cgcatcagga gggtgaatga aactgcaagg ggtaattttc gatctggatg gagtaatcac
     1141 cgataccgcg catctgcatt tccaggcgtg gcagcagatt gccgctgaaa ttggcatcag
     1201 cattgatgcg cagtttaacg aattcctaaa agggatcagc cgcgatgagt ccctgcggcg
     1261 aattctgcag cacgggggta aagagggcga ttttaaccca caggaacggg cgcaactggc
     1321 gtatcgcaaa aatctgcttt acgtccactc actgcgcgaa ctgacggtta atgctgtgct
     1381 gcctggcatt cacaatttgc tggtagatct ccgggcacag cagattccag ttgggctggc
     1441 ttctgtctcc ctgaatgcgc cgacgatttt agcagcgctg gagctgcgcg agtttttcac
     1501 cttctgcgcg gacgcttccc aactcaaaaa ttcgaaaccg gacccggaaa tctttctcgc
     1561 cgcctgtgca gggctgggcg tgccgccaca ggcatgtatc ggcattgaag atgcgcaggc
     1621 gggcattgac gccattaacg ccagcggtat gcgctcggtg gggatcggcg cgggcttaac
     1681 cggggcgcaa ttattgttgc cctcaacgga ctccctgacc tggccgcggt tatcggcctt
     1741 ctggcaaaac gtatagcaaa ggaatcaaca tggcacagct ttcgttacaa catattcaaa
     1801 agatctacga taaccaggtg catgtggtga aggacttcag cctggagatt gccgataaag
     1861 agttcatcgt gtttgtcggt ccgtcgggct gcggtaaatc gaccaccctg cgtatgattg
     1921 ccgggcttga ggagatcagc ggcggtgagc tgttgatcga cggcaaacga atgaatgacg
     1981 ttccagccaa agcacgcaat atcgcgatgg tgttccagaa ctacgcgctg tatccgcata
     2041 tgacggtcta cgacaacatg gcgtttggcc tgaagataca aaaaatcgcc aaagagatga
     2101 ttgatgagcg ggttaactgg gcggcgcaaa tcctcggcct gcgtgagtac ctgaaacgca
     2161 agccgggcgc gctttccggc gggcaacgtc agcgagtggc gcttgggcgg gcgattgtgc
     2221 gcgaagcggg cgtgttttta atggatgagc cgctctctaa cctggatgcc aagctgcgtg
     2281 tgcaaatgcg cgcagagatc agcaagctgc atcagaaact gaacaccacc atgatctacg
     2341 tgacccacga tcagaccgaa gcgatgacca tggcgacgcg gattgtcatt atgaaggatg
     2401 ggattgttca gcaggtcggt gcgccgaaaa cggtctataa ccaaccggcg aatatgtttg
     2461 ttgccggatt tattgggtca ccagcaatga attttattcg cggcacgatc gatggcgata
     2521 aattcgttac ggaaacactt aaattaacca ttcccgaaga gaaattagcg gttctgaaaa
     2581 cgcaggaaag tttacataaa cccattgtga tgggaatacg cccggaggat attcatccgg
     2641 atgcgcaaga agaaaataac atttccgcca aaattagcgt ggcggaatta accggtgcgg
     2701 aatttatgct ctacaccacg gttggggggc acgagttagt ggtccgtgct ggtgcgttaa
     2761 atgattatca tgcaggagaa aatatcacta ttcattttga tatgactaaa tgtcatttct
     2821 ttgatgcaga aacggaaata gcaatttgct aaatacaggg ggaaggcatt ctcccaggat
     2881 aatacaagga acaataatga aaaagttatt accctgtacc gcactggtga tgtgtgcggg
     2941 aatggcctgc gcacaggccg aggaaaagaa caactggcac tttaatatcg gcgcgatgta
     3001 cgaaatagaa aacgtcgagg gttatgtcga agatatggat gggctggcag agccttctgt
     3061 ctattttaat gccgccaacg ggccgtggag aatttctctg gcctattatc aggaagggcc
     3121 ggtagattat agcgcgggta aacgtggaac gtggtttgat cgcccggagc tggaggtaca
     3181 ttatcagttc ctcgaaagcg atgatttcag tctcggtctg actggtggtt tccgtaacta
     3241 tggttatcac tacgttgatg aaccgggtaa agacacggca aatatgcagc gctggaaaat
     3301 cgcgccagac tgggatgtga aactgactga cgatttacgt ttcaacggtt ggctgtcgat
     3361 gtataaattt gccaacgatc tgaatacgac cggttatgct gatacccgtg tcgaaacgga
     3421 aacgggtctg caatatacct tcaacgaaac ggttgccttg cgagtgaact attatctcga
     3481 gcgtggtttc aatatggatg atagccgcaa taacggtgag ttttccacgc aagaaattcg
     3541 cgcctatttg ccgctgacgc tcggcaacca ctcggtgacg ccgtatacgc gcattgggct
     3601 ggatcgctgg agtaactggg actggcagga tgatattgaa cgtgaaggcc atgattttaa
     3661 ccgtgtgggt ttattttacg gttatgattt ccagaatggt ctttccgttt cgctggaata
     3721 cgcgtttgag tggcaggatc acgacgaagg cgacagcgat aaattccatt atgcgggtgt
     3781 tggggtgaat tactcgttct gataatgtgc taaattgccg gatgcggggc gagcgccaaa
     3841 tccggcatac atttatttca acgacatatg cgtagcaacg gtaatatttt gtggtgacgg
     3901 ttttccggca attaactgga ataataactc gcagctttgt tgacctaact cctgcgtcgg
     3961 aacatcgatg ccgcctggtg caggcgttaa tataaacgac agcgtttcat tactataacc
     4021 caccaccgct aactgctgcg gaatagcaat gtttttctct gccgccgcac gataaatact
     4081 cattaatttc aggctgtcag tagcaaacac tgcctcaggc aacggtgact ggcttaataa
     4141 ttcccgtgct gcttttaatg ctgtctcatg ggtataaccg ccgtcaacaa tccattcatc
     4201 acgcactgca atattatgcg tagccagact ttgcttataa ccatttaccc gatccactga
     4261 aacttgtaca tcaagcggcg catgcaggca ggctatattc ttatgcccgc tttcaattaa
     4321 cgcattggtc agcgcaatac tgtcgccata attatcggta tcgacggaat aaacatggct
     4381 gtattgacct tcaactttac cgatcaccac caccgggatc tcgtatttgt cgagttgtgc
     4441 aaagaaggat tcatcggcag gcgaacttag cataataatg cctttaatca ttttctgctt
     4501 aattttgctt tcgcattttt gcagatcttc tgccggattg tgcgacgttt gtaatatcac
     4561 gtcgaaacct tcttcttctg ctttggcggt gatggcatgc aaaacttcag agaaaaatgg
     4621 attacccgcc gtagttttgg tcgaacgagt agaaatcacc ataatggcat caaaacccga
     4681 agaggtcagc gcgcgggcca gcttgtttgg ttgatactgt aattcttcaa tggcccgtaa
     4741 cactttttcg cgcgcttccg gggagatatt ggtttgctta ttcagcacgc gtgatacggt
     4801 ggattttgat acgcctgcaa ccctggcaat atcataaata gtaggggaca taggtcagga
     4861 actccgtccg aacgtgaatg ctgcacatct tatggagttc gcccgtcgat gacaacacgg
     4921 gtagttgata atcaatggcc tggcccccac attcatatcc ttacgaacga ttttttttct
     4981 ggtcttcaga gcagcacagg acagcaatga agcgacttaa aaatgaactc aatgcgctgg
     5041 tgaatcgggg tgtcgacaga catctgcgcc tcgctgtaac cggacttagc cgcagcggca
     5101 aaacagcgtt tatcaccgcg atggttaatc agttgctcaa tattcatgcc ggagcacgtt
     5161 tgccgctttt aagtgcggtg cgtgaagagc gcctgctggg cgtaaaacgc attccccagc
     5221 gtgactttgg cattccgcgc ttcacctatg atgaagggtt ggcgcagtta tatggcgatc
     5281 ctcccgcctg gccgacgcct acgcgcggtg tcagtgaaat tcgcctggcg ttacgtttta
     5341 aatcgaacga ttcgctgctg cgccacttta aggatacctc cacgctgtat ctggagattg
     5401 tggattaccc cggcgaatgg ttgctcgacc tgccgatgct ggcgcaggac tatttaagct
     5461 ggtcgcgcca gatgacgggc ttactcaatg gtcagcgcgg cgaatggtcg gcgaaatggc
     5521 gaatgatgtg cgaagggctg gacccgctag cgcctgccga cgaaaaccgg ctggcagaca
     5581 ttgccgccgc ctggaccgag tatctccatc actgcaaaca gcaggggttg cactttattc
     5641 agcctgggcg ctttgtcttg ccgggagata tggcaggagc acccgcgctg caattcttcc
     5701 cgtggccgga tgtcgatgcc tggggcgagt ccaaactggc gcaggccgat aagcacacta
     5761 atgccggaat gttgcgcgag cggtttaatt attactgcga gaaagtggtg aaggggttct
     5821 ataagaatca ttttctgcgc tttgaccgcc agattgtgct ggtggattgc ctgcaacctc
     5881 tcaacagtgg gccacaggca tttaatgata tgcgtctggc gctgacgcag ctgatgcaaa
     5941 gtttccacta cgggcagcgt accctgttcc ggcgtttgtt ttcgccggtt atcgataagc
     6001 tattgtttgc tgccactaaa gcggaccatg tgaccatcga tcagcacgcc aatatggttt
     6061 cattgctgca acaactgatt caggatgcat ggcaaaatgc ggcgttcgaa gggatcagta
     6121 tggactgcct ggggctggcg tctgttcagg cgaccaccag cggaatgatt gatgttaacg
     6181 gtgagaaaat cccggcgctg cgcggtaatc gactcagcga tggcgcaccg ctcactgttt
     6241 atcctggcga agttcccgca cgtttgccag gtcaggcgtt ctgggataag caaggcttcc
     6301 agtttgaggc gtttcgtccg caggtgatgg atgtcgacaa accgctaccg catattcgtc
     6361 ttgatgctgc gctggaattt ttaataggag ataaattgcg atgaccgaac cgttaaaacc
     6421 acgtattgat ttcgacggtc cactggaggt cgatcagaat ccaaaattca gggcgcagca
     6481 gacctttgac gaaaatcagg cgcaaaattt tgccccggcc acgctcgacg aagcacagga
     6541 agaagagggg caagttgaag cggtgatgga cgcagcgtta cgtccgaaac gcagcctgtg
     6601 gcgcaaaatg gtgatgggcg ggctggctct gtttggcgca agcgttgtcg ggcagggcgt
     6661 gcagtggaca atgaacgcct ggcaaaccca ggactgggtg gcgctgggtg gatgtgccgc
     6721 tggggcattg attatcggcg ctggcgtagg ttctgtggta acagagtggc ggcgcttatg
     6781 gcgcttgcga cagcgcgccc atgaacgcga tgaagcgcgc gatttgttgc acagtcacgg
     6841 cacgggtaaa ggccgtgcat tctgcgaaaa actggcgcag caggcgggca tcgatcagtc
     6901 acatccggcg ctgcagcgct ggtatgcctc aatccatgaa acgcagaacg atcgtgaagt
     6961 ggtcagtttg tatgctcacc tggtccagcc agttttagat gcccaggcgc ggcgcgaaat
     7021 cagccgctca gcggcggaat caacgttaat gattgccgtt agcccactgg cgctggtgga
     7081 tatggcgttt atcgcctggc gcaatctgcg tttgattaat cgcatcgcca cgctgtatgg
     7141 cattgaactg ggatattaca gccgtttgcg cctgtttaag ctggtattgc tgaatatcgc
     7201 tttcgccgga gccagcgaac tggtgcgcga agtggggatg gactggatgt cgcaagatct
     7261 cgctgcgcgt ttgtctaccc gggcagctca ggggattggt gctggacttc tgacggcacg
     7321 actcgggatt aaagctatgg agctttgccg cccgctgccg tggattgacg atgacaagcc
     7381 acgcctcggg gatttccgtc gtcagcttat cggtcaggtg aaagaaactc tgcaaaaagg
     7441 caaaacgccc agcgaaaaat aatgcaatat cgggtgctga ccggatatct ttacgccgaa
     7501 gtgcccgttt ttccgtcttt gtgtcaatga ttgttgacag aaaccttcct gctatccaaa
     7561 tagtgtcata tcatcatatt aattgttctt ttttcaggtg aaggttccca tgcgtctgga
     7621 agtcttttgt gaagaccgac tcggtctgac ccgcgaatta ctcgatctac tcgtgctaag
     7681 aggcattgat ttacgcggta ttgagattga ccccattggg cgaatctacc tcaattttgc
     7741 tgaactggag tttgagagtt tcagcagtct gatggccgaa atacgccgta ttgcaggtgt
     7801 taccgatgtg cgtactgtcc cgtggatgcc ttccgaacgt gagcatctgg cgttgagcgc
     7861 gttactggag gcgttgcctg aacctgtgct ctctgtcgat atgaaaagca aagtggatat
     7921 ggcgaacccg gcgagctgtc agctttttgg gcaaaaattg gatcgcctgc gcaaccatac
     7981 cgccgcgcaa ttgattaacg gctttaattt tttacgctgg ctggaaagcg aaccgcaaga
     8041 ttcgcataac gagcatgtcg ttattaatgg gcagaatttc ctgatggaga ttacgcctgt
     8101 ttatcttcag gatgaaaatg atcaacacgt cctgaccggt gcggtggtga tgctgcgatc
     8161 aacgattcgt atgggccgtc agttgcaaaa tgtcgccgcc caggatgtca gcgccttcag
     8221 tcaaattgtc gctgtcagcc cgaaaatgaa gcatgttgtc gaacaggcgc agaaactggc
     8281 gatgctaagc gcgccactgc tgattacggg tgataccggc accggaaaag atctctttgc
     8341 ctacgcctgt catcaggcaa gccccagagc gagcaaacct tacctggcgc tgaactgtgc
     8401 gtctataccg gaagatgcgg tcgagagtga actgtttggt catgctccgg aagggaagaa
     8461 agggttcttt gagcaggcga acggtggttc ggtgctgttg gatgaaatag gtgagatgtc
     8521 accacggatg caggcgaaat tactgcgttt ccttaatgat ggcaccttcc gtcgggttgg
     8581 cgaagaccat gaggtgcatg tcgatgtgcg ggtgatttgc gctacgcaga agaatctggt
     8641 cgaactggtg caaaaaggcg tgttccgtga agatctctat tatcgtctga acgtgttgac
     8701 gctcaatctg ccgccgctac gtgactgtcc gcaggacatc atgccgttaa ccgagctgtt
     8761 cgtcgcccgc tttgccgacg agcagggcgt gccgcgtccg aaactggccg ctgatctgaa
     8821 tactgtactt acgcgttatg cgtggccggg aaatgtgcgg cagttaaaga acgctatcta
     8881 tcgtgcactg acacaactgg acggttatga gctgcgtcca caggatattt tgttgccgga
     8941 ttatgacgcc gcaacggtag ccgtgggcga agatgcgatg gaaggttcgc tggacgaaat
     9001 caccagccgt tttgaacgct cggtattaac ccagctttat cgcaattatc ccagcacgcg
     9061 caaactggca aaacgtctcg gcgtttcaca taccgcgatt gccaataagt tgcgggaata
     9121 tggtctgagt cagaagaaga acgaagagta agcgtgaata tgcctgatgg tgcaatacca
     9181 tcaggcatat taacttatgc tttcagtaca gccagagctg cttcgtaatc cggctcggtg
     9241 gtgatttcat ccaccagctg gctgaaaatc acattgtcat tttcatcaat aaccacaacg
     9301 gcacgcgctg ccagaccttt cagtgggcca tcagcaattg ccacaccgta ggcttgcagg
     9361 aattcagcgt tacggaaagt ggagagggtg ataacgttgt tcagaccttc tgcgccgcag
     9421 aaacgagact gggcgaacgg cagatcggca gagatacaca gcacaacggt gttgtcgatc
     9481 tcggttgcca gttggttaaa cttacgtact gatgcggcgc aaacaccggt atcaatactc
     9541 gggaaaatgt tcagcacttt gcgtttaccc gcaaactgac cgagggtgac gtcagacaga
     9601 tcttttgcca cgagagtaaa agtctgcgct ttgctacccg cctgcgggat ggaattggcg
     9661 actgtaaccg ggttgccctg gaaatgaacg gtttgtgaca tgattatctt tcctgtttac
     9721 atatagttaa cgtcacacct agtttatgct aactgtcaat aacacagcaa acgctatttg
     9781 cgcttaatcc gcagaccacc gcgacaacaa ggagtaaaga tgagaaccgt taaggtattt
     9841 gaggaggcct ggcccttaca taccccgttt gtgattgctc ggggaagtcg cagtgaagcg
     9901 cgcgtggtgg tggttgaact ggaagaagag ggtatcaaag gcaccggtga atgcacgccg
     9961 tatccgcgtt atggggaaag cgatgcctcg gtaatggcgc aaattatgag cgtcgtgccg
    10021 caactagaga aagggctgac acgggaggag ttgcaaaaaa tcctccctgc cggcgcagca
    10081 cgtaatgcgc tggattgtgc attgtgggat ctggcggcgc gaaaacagca gcaatcgctg
    10141 gctgatttga tcggcataac gcttcccgag acagtcacca cggcacagac gatagtcatc
    10201 ggtacgcctg atcagatggc caatagtgca tcaacactct ggcaggcagg cgcgaaatta
    10261 ctgaaagtga agctggataa ccatcttatc agtgagcgga tggtggcaat tcgcacagct
    10321 gtgcccgatg cgacgctgat cgttgatgca aatgaatcct ggcgtgcaga agggttggcg
    10381 gcgcgttgcc agctattggc ggatttaggc gttgcgatgc ttgaacaacc gcttcctgcg
    10441 caggacgatg cggcgctgga gaattttatt catccgttac cgatttgtgc tgatgaaagt
    10501 tgtcatactc gtagcaatct gaaggcgctg aaagggcgct atgagatggt taacattaag
    10561 cttgataaaa ccggtggtct gacggaagcg ctggcgctgg cgactgaagc gcgtgcacaa
    10621 ggttttcgtc tgatgctggg ctgcatgttg tgtacctctc gtgccattag cgccgcttta
    10681 ccgctggtgc cgcaggtcag tttcgccgat cttgacggac cgacctggct ggcggtagat
    10741 gtggaaccgg cgcttcagtt cacgacgggc gaattgcatc tttaggatgc cagcgcagca
    10801 agtttgccat cgcaaagaga tatttttcgc tggcttcgtc ggaggagatg ggtggaaact
    10861 ctgcggtgat gcaatgcaag ttgagatctg cacaccaact gccgaaagag ccaggcgttt
    10921 cataaccgac gctggttacc agaggcaatt caaacgcctg ggccagccat tcacctaatt
    10981 cgctgtgtct gggatcttca atacaggcca gcggatcgtg gaatgagacc acccaggcag
    11041 gttgaatgcg gtgtataagc tggcacagcg cctgggtttc aggttcggag ccaggtttgt
    11101 cacctgtcag taatacaaca tcacgttctt cagcggcgct gttccagcga taaactgttt
    11161 caccttcctt ccagttcgct gccggaaagt ttcggtttaa atccacacca ttagcattgg
    11221 cccgtaaccc taactggcag ccgtcaggat tcacacacag caccacatga tggcggcgca
    11281 aagaaggtgt caaagtccgc agagcacagg agagcgtgac gatcgaagag ttttcatcac
    11341 cgtgagtgcc agccagaatc aaaccacttt cgtgactggc tgcaggggcc ggaaaccaga
    11401 ttaacggcgc gcccaataat gaacgtccgt aatgttctgt tccgggcgga aatgcgccgc
    11461 gttcggcgcg tgggcgagtt acggtcatga tcgtctctgg ttcaggaagt attacaggca
    11521 gtgttgtgca aattttgcgg attatcaaat ccttttcttc aacgctatgt catcgatctt
    11581 gtatcacttt tttgccggaa gttgtttgca ttttcattga tgtgcagata ttagaattgt
    11641 cgtaatgtta tatacatggc gtattttatt cttactggtt ctacacatgt taatcgcatc
    11701 tgattgatca gttcacctta ataagtttaa taaatcgtac tgcacatagt acagtacgat
    11761 ggtagctata taattgattt acatgaagaa gggcttatca ccatcagtcc cgggttgatt
    11821 gatgcctata ttctcaccaa tgtgtttctc aggtttatcg atgatatctg tgattaatgc
    11881 tgcgacactc ttacgtgata cgatcgtacc tttgaatggt tcattgcgtg aggtaagctc
    11941 ataatcaata atatcttcat cagtcagcca ggcagggcga agaattgtat attccagtcc
    12001 agaagcctca attgcatccg cagccctgcg gaatggtttt aggggttcac caataactgc
    12061 attattccat tcgccaaatt ttcctggaac ttcatcataa ataccgaggg aaagaacaaa
    12121 gatcagacgt ttaacatcac aggctttcat cgcagcgatc actgaatttg cctgaatatc
    12181 taaatcttcc cccgtaaggt tggcatacac aacatcctgt ccctgcatgg cctgcttcag
    12241 tgctgcatga ttcagtacat cccccataat aatcttgcta ttagttggat agggtttgtg
    12301 gatttttgct ggctgacggg caaataaagt ttgtttaatg gtttgtttat ctgccagttg
    12361 attaatcaca tggcgggcta tctgaccgcc agcaccaaga atcagtacat ttttcatgaa
    12421 acttttccca gattattggc agcaatatgc caggccatat cactattacg gatttgaata
    12481 tgtttcatta cagagtttcc tcaaagaacg gagctaatac tgaaattact tcagccacat
    12541 agactttgcc atcataaaga tccatatggt ttgcgccttc aacaatgtga tagcgtttat
    12601 cctggcttga tgctcgatcg tacaggtcgt cactcatcca tttgctccca gccaggctgc
    12661 ccgccacaat ctgtatcggc tgagtcaggt acacttccgc catatggtaa gcatcatagg
    12721 taataatctg gttaaggctg cgcaaagtag cgtaacccgg tgctgttgga tactgcgcgc
    12781 gaggggtgtg gtaatattcc caggcctgac gcagttcttc gttcggcgca tcggactcct
    12841 tcattggtgc cagtggcata gtggcgtatt ctccgctgct aatatcgctg gttcgggcgt
    12901 ttgaacccgc gtcaacgtat ggtagggcat caatagattt cacattgttt tcccaaccat
    12961 tacggaacat cgaaccaata ttgaccgcac taacagtacc gatggccttg atgcggcgat
    13021 cctgaattgc agcattggct gtatatcctg caccggcaca aattcccatc gcaccaattc
    13081 gggtattgtc gacataagaa agcgttgtca ggtaatcaat cacggcactg acgtcttcag
    13141 tacgaatgta tgggttttct aactgacgcg gctcgccgcc gctttcacct tgataagatg
    13201 cgtcataagc aatagtgaca aatccttttt ccgccagttt ttcggcatag gttccggccg
    13261 tttgctcttt aacgccccca cctgggtgag ataccacaat tgccggatac tgacgggttt
    13321 catcaaattt tggagggaaa tagatcactg cagacaaaga gatggttgga ttattgctgt
    13381 tagtgaagct gactttatta ttcatcattc cgttcctcat ggagttgtcg gttcgtttta
    13441 acggttggtg atatcactat agatattgat cattaagttg attagaccca aaatcatgat
    13501 tagacctatc atttaaatga ttaatagatt gtatggagat actgaatgaa gcgtgaagaa
    13561 atcgctgatc tgatggcgtt tgtcgttgtt gcagaggagc gtagcttcac tcgcgcagca
    13621 gcccgcctga gcatggcgca gtcagcttta agccagatag tgcgccgtat agaagaacga
    13681 ttgggattgc ggcttctgac gcgaaccacg cgcagcgttg tacccactga agcgggcgag
    13741 catcttttgt ctgttcttgg ccctatgttg catgacatag attctgccct gacatccctg
    13801 agcgatctgc agaaccgccc atccgggaca atacgtatta ctactgtaga acatgcagca
    13861 aaaacgatat tgttaccagc catgcgcaca ttcctgaaat cgcatcctga aattgatatt
    13921 cagcttacca ttgattatgg tttgaccgat gtcgtttctg aacgttttga tgcaggcgtc
    13981 cgtctgggtg gggagatgga taaagatatg atcgccattc gaatcgggcc agacatacca
    14041 atggctattg ttggctcacc ggattatttt tctcgtcgaa gtgctccaac gtcagtgtca
    14101 caattaatag atcatcaggc aattaatttg tatcttccca catcgggtac agcaaatcgc
    14161 tggagattaa tacgcggtgg acgtgaagtt cgtgttcgca tggaaggtca gcttttactg
    14221 aatacgatag atctgatcat tgatgctgca attgatgggc atggattggc gtatctacct
    14281 tatgatcagg tggagcgggc tattaaagaa aaaaaactga tacgtgtttt ggataaattc
    14341 acaccagatt tacccggtta tcacctgtac tatccacacc gtcgacatgc tggctcggca
    14401 ttctcattat ttatagatag gctgaagtat aaaggtgctg tttagcacta cttgctgata
    14461 cattaattta attcttctct taacgtattc tcagttcctt tcaacgtttt ggttattttt
    14521 tattcttcgc acaatggcga cagatgctga ttatgatacc gaaaacgggt ttgaatgtgc
    14581 gaagcccgaa cgtagtg
//
LOCUS       DAFGPF010000120        14204 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFGPF010000120 DAFGPF010000000
VERSION     DAFGPF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14204
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.120"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            46..861
                     /gene="gspC"
                     /locus_tag="LSX49_004127"
     CDS             46..861
                     /gene="gspC"
                     /locus_tag="LSX49_004127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HBL7170462.1"
                     /translation="MPTLPFPFHLANHNKDAAINILITFISIGLIIFNVNYFHTTIVK
                     NEQIINQPTNAFQSEFSLAALWRNENHTGVKDANPVAVNQETPKLSIALNGIVLTSND
                     ETSFVLINEGNEQKRYSLNEALESAPGTFIRKINKTSVVFETHGHYEKVTLHPGLPDI
                     IKQPDSENQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNL
                     SLTHPDEISQALSLLLTQQSAQFTIRRNGVPRLINVSVAELTGMNGQRNEGTQ"
     gene            845..2797
                     /gene="gspD"
                     /locus_tag="LSX49_004128"
     CDS             845..2797
                     /gene="gspD"
                     /locus_tag="LSX49_004128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HBL7170463.1"
                     /translation="MKGLNKITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIV
                     GQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVR
                     SANVKTSPGMIADSSRPGVGDELVTRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYE
                     PSNVLILTGRASTINKLIEVIKRVDVIGTEKQQIIHLEYASAEDLAEILNQLISESHG
                     KSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNTRVYYLKYA
                     KATNLVEVLTGVSEKLKDEKGNSRKPSSTSAMDNVAITADEQTNSLVITADQSVQEKL
                     ATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPVFNAAQG
                     VADYKKNGGITSANPAWDMFSAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVT
                     LDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERKTVGTKLKVTPQVNEGDAVLLEIE
                     QEVSSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI
                     PLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLSKEKYTRYRQEQQLRIDGKSK
                     ALVGSEDLPVLNENTFNSHAPAPSSR"
     gene            2807..4288
                     /gene="gspE"
                     /locus_tag="LSX49_004129"
     CDS             2807..4288
                     /gene="gspE"
                     /locus_tag="LSX49_004129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HBL7170464.1"
                     /translation="MRIHSPYPASWALAQRIGYLYSEGEIIYLADTPFERLLDIQRQV
                     GQCQTMTSLSQADFEARLEAVFHQNTGESQQIAQDIDQSVDLLSLSEEMPANEDLLNE
                     DSAAPVIRLINAILSEAIKETASDIHIETYEKTMSIRFRIDGVLRTILQPNKKLAALL
                     ISRIKVMARLDIAEKRIPQDGRISLRIGRRNIDVRVSTLPSIYGERAVLRLLDKNSLQ
                     LSLNNLGMTAADKQDLENLIQLPHGIILVTGPTGSGKSTTLYAILSALNIPGRNILTV
                     EDPVEYELEGIGQTQVNTRVDMSFARGLRAILRQDPDVVMVGEIRDTETAQIAVQASL
                     TGHLVLSTLHTNSASGAVTRLRDMGVESFLLSSSLAGIIAQRLVRRLCPQCRQFTPVS
                     PQQAQMFKYHQLAVTTIGTPVGCPHCHQSGYQGRMAIHEMMVVTPELRAAIHENVDEQ
                     ALERLVRQQHNALIKNGLQTVIRGDTSWDEVMRVASATLENKA"
     gene            4285..5481
                     /gene="gspF"
                     /locus_tag="LSX49_004130"
     CDS             4285..5481
                     /gene="gspF"
                     /locus_tag="LSX49_004130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HBL7170465.1"
                     /translation="MNYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQ
                     KSSGVKTRRPRISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLADVLNQVR
                     SAILEGHPLSDALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKL
                     IQSLIYPCMLTTVAIVVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRTG
                     PTLLATVFIVAVGFWLWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQS
                     SGVPLLDGMNLSTESLNNLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVAS
                     GEKSGQLGTLMVRAADNQETLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQ
                     LNSMIN"
     gene            5491..5928
                     /gene="gspG"
                     /locus_tag="LSX49_004131"
     CDS             5491..5928
                     /gene="gspG"
                     /locus_tag="LSX49_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HBL7170466.1"
                     /translation="MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQK
                     AVSDIVALENALDMYKLDNHRYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADP
                     WGNDYVLVNPGEHGAYDLLSAGPDGEMGTEDDITNWGLSKKKK"
     gene            5936..6445
                     /gene="gspH"
                     /locus_tag="LSX49_004132"
     CDS             5936..6445
                     /gene="gspH"
                     /locus_tag="LSX49_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HBL7170467.1"
                     /translation="MNQQRGFTLLEMMLVLALVAITASVVLFTYGREDAASTRARETA
                     ARFTAALELAIDRATLSGQPVGIHFSDSAWRIMVPGKTPSAWRWVPLQEDAADESKND
                     WGEELSIQLQPFKPDDSNQPQVVILADGQITPFSLLMANTGTGEPLLTLVSSGSWPLD
                     QTLARDTRP"
     gene            6442..6819
                     /gene="gspI"
                     /locus_tag="LSX49_004133"
     CDS             6442..6819
                     /gene="gspI"
                     /locus_tag="LSX49_004133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417789.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HBL7170468.1"
                     /translation="MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQRTAIERMRNET
                     LALWIADNQLQSQDSFDEENTSSSGKELINGEEWNWRSDIHSSKDGTLLERTITVTLP
                     SGQTTSLTRYQSINNKSGQAQDD"
     gene            6812..7399
                     /gene="gspJ"
                     /locus_tag="LSX49_004134"
     CDS             6812..7399
                     /gene="gspJ"
                     /locus_tag="LSX49_004134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HBL7170469.1"
                     /translation="MINRQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKE
                     IQQFNQLQRTITILDNDLLQLVARRNRSTDKIMVLGEEAIFTTQSRDPLAPLSEAQTL
                     LTVHWYLRNHTLYRAVRTSVDGRKDQPAQAMLEHVESFLLESNSGESQELPLSVTLHL
                     KTQQYGALQRRFALPEQLAREESPAQTQAGNNNHE"
     gene            7392..8375
                     /gene="gspK"
                     /locus_tag="LSX49_004135"
     CDS             7392..8375
                     /gene="gspK"
                     /locus_tag="LSX49_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HBL7170470.1"
                     /translation="MNNEQRGVALLIVLMLLALMAALAADMTISFHGQLHRTRQVNHH
                     LQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLENGNTVKWQLRDAQH
                     CFNLNALAKISDAPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDADDSPRF
                     HGAEDNFYQSQTPPRHSANQMLFLTGELRQIKGITENIYQRLIPYVCVLPTSELSINL
                     NMLTENDIPLFRALFLNNITDADARVLLQKRPREGWLTTDAFLYWAQQDFSGVKPLVA
                     QVKGHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQSAQIYRRTLQLY"
     gene            8390..9553
                     /gene="gspL"
                     /locus_tag="LSX49_004136"
     CDS             8390..9553
                     /gene="gspL"
                     /locus_tag="LSX49_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HBL7170471.1"
                     /translation="MPESLMVIRSFSTLRKHWEWMTFSADSVSSVHTLTDDLPLGSLA
                     DQPGAGNVHLLIPPEGLLYRSLTLPNAKYKLTAQTLQWLAEETLPDASQNWHWTVVDK
                     QNESVEVIGIQSEKLSRYLERLHTAGLNVTRVLPDGCYLPWEVDSWTLVNQQTSWLIR
                     SAAHAFNELDEHWLQHLANQFPPENMRCYGVAPHGVAAANPLIQHPEIPSLSLYSADI
                     AFQRYDMLHGVFRKQKTVGKSGKWLTRLAVSCLVLAILSFVGSRGIALWQTLKIEDQL
                     QQQQQETWQRYFPQIKHTHNFRFYFKQQLAQQYPEAVPLLYHLQTLLLEHSELQLMEA
                     NYSQRQKSLTLKMSAKSEANIDRFCELTQSWLPMEKTEKDPVSGVWTVRNSGK"
     gene            9550..10011
                     /gene="gspM"
                     /locus_tag="LSX49_004137"
     CDS             9550..10011
                     /gene="gspM"
                     /locus_tag="LSX49_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspM"
                     /protein_id="HBL7170472.1"
                     /translation="MIKSWWAEKSTSEKQIIAALAVLSLGVFCWLAVIKPIDTYIEEH
                     QSHAQKIKKDIKWMQDQASTHGLLGHPALTQPIKNILLEEAKRENLTITLENGPDNTL
                     TINPVTAPLENVSRWLTTAQITYGIVIEDLQFTLAGNEEITLKHLSFREQQ"
     gene            10011..10683
                     /gene="gspO"
                     /locus_tag="LSX49_004138"
                     /pseudo
     CDS             10011..10683
                     /gene="gspO"
                     /locus_tag="LSX49_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase GspO"
     gene            complement(10712..11188)
                     /gene="bfr"
                     /locus_tag="LSX49_004139"
     CDS             complement(10712..11188)
                     /gene="bfr"
                     /locus_tag="LSX49_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HBL7170473.1"
                     /translation="MKGDTKVINYLNKLLGNELVAINQYFLHARMFKNWGLKRLNDVE
                     YHESIDEMKHADRYIERILFLEGLPNLQDLGKLNIGEDVEEMLRSDLALELDGAKNLR
                     EAIGYADSVHDYVSRDMMIEILRDEEGHIDWLETELDLIQKMGLQNYLQAQIREEG"
     gene            complement(11260..11454)
                     /gene="bfd"
                     /locus_tag="LSX49_004140"
     CDS             complement(11260..11454)
                     /gene="bfd"
                     /locus_tag="LSX49_004140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HBL7170474.1"
                     /translation="MYVCLCNGISDKKIRQAVRQFSPHSFQQLKKFIPVGNQCGKCVR
                     AAREVMEDELMQLPEFKESA"
     gene            complement(11623..>14204)
                     /gene="chiA"
                     /locus_tag="LSX49_004141"
     CDS             complement(11623..>14204)
                     /gene="chiA"
                     /locus_tag="LSX49_004141"
                     /EC_number="3.2.1.14"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bifunctional chitinase/lysozyme"
                     /protein_id="HBL7170475.1"
                     /translation="DGKIYENAWWVSSTNCPGKAKANDATNPWRLKRTATAAEISQFG
                     NTLSCEKSGSSSSSTSNTPASNTPANGGSATPAQGTVPSNSSVVAWNKQQGGQTWYVV
                     FNGAVYKNAWWVASSNCPGDAKGNDASNPWRYVRAATATEISETSNPQSCTSAPQPAP
                     DVKPAPDVKPAPDVQPAPADKSNDNYAVVAWKGQEGSSTWYVIYNGSIYKNAWWVGAA
                     NCPGDAKENDASNPWRYVRAATATEITQYGNPGSCSVKPDNNGGAVTPVDPTPETPET
                     PVTPTPDNNEPSTPADSSNDYSLQAWSGQEGSEIYHVIFNGNVYQNAWWVGSEDCPRG
                     TSVENSNNPWRLVRTATAAEMSQYGNPTTCEIDNGGVIIVDGFQASKAYSANSIVDYN
                     DAHYKTSVDQDAWGFVPGGDNPWKKYEPAKAWSASTVYVKGDRVVVDGQAYEALFWTQ
                     SDNPALVANQNATGSNSRPWKPLGKTQSYSNEELNNAPQFNPETLYASDTLIRFNGEN
                     YISQSKVQKVSPSDSNPWRVFVDWTGTKERVGTPKKAWPKHVYAPYVDFTLNTIPDLA
                     ALAKNHNVNHFTLAFVVSKDANTCLPTWGTAYGMQNYAQYSKIKALREAGGDVMLSIG
                     GANNAPLAASCKNVDDLMQHYYDIVDNLNLRVLDFDIEGTWVADQASIERRNLAVKKV
                     QDKWKSEGKDIAIWYTLPILPTGLTPEGMNVLSDAKAKGVELAGVNVMTMDYGNAICQ
                     SANTEGQNIHGKCATSAIANLHAQLKGLYGNKSDAEIDAMMGTTPMVGVNDVQGEVFY
                     LSDARLVMQDAQKRNLGMVGIWSIARDLPGGTNLSPEFHGLTKEQAPKYAFSEIFAPF
                     TKQ"
BASE COUNT         3665 a         3654 c         3355 g         3530 t
ORIGIN      
        1 cgtcaatata caacccaccc aatctatttt attagaacat acatcgtgcc cacactacct
       61 ttccccttcc atctggcgaa tcataataaa gatgctgcca tcaatatatt gattacattt
      121 ataagcatag ggctgattat ttttaatgtg aattatttcc atacaactat agttaaaaat
      181 gaacagatca ttaatcaacc aacaaatgca tttcagtctg aattcagcct tgccgcttta
      241 tggcgcaacg aaaatcatac tggggtaaaa gatgcaaatc ccgtggcagt taatcaggaa
      301 acacctaagc tctctatagc gcttaatggc attgtactca catcgaatga tgagacttct
      361 tttgtcttaa ttaatgaggg gaacgaacaa aagcgatact ccctcaacga agcccttgag
      421 tcagcgccgg gaacgtttat tagaaaaata aataaaacca gcgttgtgtt tgaaactcac
      481 gggcattacg aaaaagtaac tctccatcca gggctacctg acatcatcaa gcagcctgat
      541 tcggaaaatc aaaatgtact cgccgattat attatcgcca cacctatacg tgatggagaa
      601 cagatatacg gtcttcgatt gaatcctcgt aagggtctca atgcatttac caccagtttg
      661 ctgcaacctg gggatatcgc cctcaggatc aataatcttt cgctgaccca ccctgatgag
      721 atttcacagg cattaagttt actgctaact caacaaagtg ctcagtttac aattcgtcgc
      781 aacggcgtac cccgcttgat aaatgtttcc gtcgcggaac ttacaggaat gaatggacag
      841 cgcaatgaag ggactcaata aaatcacctg ctgcttgctg gcagcattac tcatgccttg
      901 tgcaggacac gctgagaacg aacaatacgg cgctaacttc aataacgccg atatccgcca
      961 gttcgtggaa atagtgggtc agcatcttgg caaaacgatc ctgatcgacc cttcggtaca
     1021 gggaaccatt tccgtacgca gtaatgatac gtttagccaa caggagtact accagttctt
     1081 tttaagtatt cttgatcttt acggttattc cgtgatcacg ctggacaatg gttttctgaa
     1141 agtggtgcgc tcagctaatg taaaaacatc gccagggatg attgctgaca gttctcgtcc
     1201 aggcgtaggt gatgagttgg tcacccgaat cgtaccgctt gagaacgttc ctgctcgtga
     1261 cctggctccc ctgctccgcc agatgatgga tgcgggtagc gtcggtaatg ttgtgcatta
     1321 tgaaccctcc aacgttctta ttctgaccgg tcgtgcctcc accattaata aactgattga
     1381 agtcataaag cgcgttgatg tcatcggcac agagaagcag caaattattc atctggaata
     1441 tgcatcagcg gaagatctcg ccgagattct taatcaatta atcagcgaaa gccacggtaa
     1501 aagccagatg cctgccctcc tttccgcgaa gattgtggcg gataagcgaa ccaactctct
     1561 tatcatcagc ggaccggaaa aagcacgcca gcgcataact tcattactga aaagccttga
     1621 tgtagaagag agcgaggaag gaaatacccg ggtctattac ctgaaatatg ctaaagccac
     1681 gaatctggtg gaagtgctaa ccggtgtttc cgaaaagctg aaagatgaaa aagggaattc
     1741 gcgtaagcct tcttctactt ctgcgatgga taatgtggcc attaccgccg atgaacagac
     1801 caactcgttg gtcattaccg ctgaccagtc cgtccaggag aaactcgcca cggtaattgc
     1861 gcgtctggat attcgccgtg cacaggtgct ggttgaggca atcatcgtcg aagttcagga
     1921 tggaaatgga ctcaacctcg gcgtgcaatg ggcgaataaa aacgttggcg cacagcaatt
     1981 taccaatacg ggattaccgg tttttaacgc tgcgcaaggt gtagctgatt ataaaaagaa
     2041 tggcgggatc accagcgcga atcctgcctg ggatatgttt agcgcctaca atggcatggc
     2101 tgcaggcttc ttcaatggcg actggggcgt attgttgact gcgctggcca gtaacaataa
     2161 aaatgacatc ctcgccaccc cgagcatcgt aacgctggat aataaactcg cgtccttcaa
     2221 cgttggtcag gatgtgccgg tgctatccgg ctctcagacc acttctgggg ataacgtctt
     2281 taatactgtc gaacgcaaaa cggtgggcac aaaactcaaa gtcactccgc aggtcaatga
     2341 aggcgacgcg gtactgctcg aaatagaaca ggaggtttcc agcgttgact cttcgtctaa
     2401 ttcgacgctc ggcccgacat ttaacacccg tactattcaa aacgccgtgc tggttaaaac
     2461 cggtgaaacg gtggtcctgg gcggattgct ggatgatttt tctaaagagc aagtgtcaaa
     2521 ggttcctctg cttggcgata ttcctttagt gggacaactc ttccgctata cctcgaccga
     2581 gcgcgctaaa cgcaacctga tggtattcat ccgcccgacg attatccgtg acgatgatgt
     2641 ttatcgctca ctgtcaaaag agaaatacac ccgctaccgt caggagcaac agctgcgaat
     2701 cgacgggaaa tcaaaagcgc tggttggctc ggaagatttg ccggtgctga atgagaacac
     2761 gttcaacagt cacgcccctg cgccatcgtc acggtgaggc attcttatga gaattcactc
     2821 accgtacccc gccagttggg cgctggcaca acgaattggt tatctctatt cagagggcga
     2881 gattatttat ctcgccgata cgccattcga acggttactc gatattcaac gtcaagttgg
     2941 tcagtgccag accatgacca gcttgtcaca ggctgatttt gaagcccgac tggaagcggt
     3001 gttccatcag aataccggtg agtcgcaaca gattgcgcag gatatcgatc aatccgtcga
     3061 tcttctctcg ctttcggaag agatgcccgc aaatgaagat ctcctgaatg aagattcagc
     3121 ggcaccggtt atccgcttga tcaatgctat tttgagtgag gccatcaaag aaaccgcctc
     3181 cgatatccac attgaaacct atgaaaaaac aatgtcgatc cgttttcgca tcgacggcgt
     3241 tttgcggaca attttacagc ccaacaaaaa actggcggca ctgcttatct cccgaattaa
     3301 ggtcatggct cgtcttgata tcgccgaaaa acgtattcca caggatggaa ggatcagttt
     3361 gcgtatcggg cgacgtaaca tagatgtccg cgtatccaca ctgccatcca tctatggtga
     3421 acgcgctgtg ctccgtctgc tggataaaaa cagcctccag ctttcattga acaacctggg
     3481 gatgacggca gcggataaac aggatttaga aaatctcatt cagcttccgc acggtattat
     3541 cctggtgaca gggccgacag gctccggtaa aagcaccacg ctctacgcca tcctttcggc
     3601 gcttaatatc cctggccgta atattctgac ggtagaagat cccgtggaat atgagctgga
     3661 aggcattgga caaacgcagg tgaatacccg tgtggatatg tctttcgctc gcggcctgcg
     3721 cgccatactt cgccaggacc cggatgtcgt catggtgggg gaaattcgtg atacagaaac
     3781 cgcgcaaatt gcggttcagg cctcgctcac aggccatctg gtactctcaa cactccacac
     3841 taacagtgca tcaggcgcag tcacccggct acgcgacatg ggcgtcgaat cattcctgct
     3901 ttcatcttca ctggcaggga ttatcgcgca acgtctggtt cgtcgtctgt gtccgcaatg
     3961 ccgacaattc acgcccgtat cgccccagca agcgcagatg tttaaatatc atcagctcgc
     4021 ggtgacaaca attggcactc ccgtaggttg ccctcattgc catcaatccg gttatcaggg
     4081 gcgcatggcg atccacgaaa tgatggtggt gacgccggaa ttgcgggccg ctattcatga
     4141 aaatgtggat gaacaagcac tggagcgact ggtccggcaa caacacaatg ccttaatcaa
     4201 aaatggcctg caaacagtga tacgcggtga cacctcctgg gatgaggtta tgcgcgtcgc
     4261 cagtgctacg ctggagaaca aagcatgaat tatcgctatc gcgccatgac ccaggatggt
     4321 caaaaattgc aggggatcat tgatgctaac gatgaacgtc aggcacgact gcggctgcgt
     4381 gaagaagggc ttttcctgtt ggatattcgc ccccaaaaaa gttcgggagt aaaaacacgt
     4441 cgcccgagga tcagccatag tgaactgacg cttttcaccc ggcagttggc aaccttaagc
     4501 gcagcggcat tacccctgga agagagcctt gccgtaattg gtcaacaaag cagtaataaa
     4561 cgactggctg acgtgttaaa tcaggtacgc agcgccatcc ttgaagggca tcccctttca
     4621 gatgcattac agcatttccc cacgcttttc gattcgctct accgtaccct ggtaaaagcg
     4681 ggcgaaaaga gcggtctgct ggccccggtg ttggaaaagc tggctgatta caatgaaaac
     4741 cggcagaaaa tccgcagcaa gctcattcag tcactgatct acccctgcat gctcactacg
     4801 gtggcgattg tggtcgtgat tattctcctc actgctgtcg tgcccaaaat taccgaacag
     4861 ttcgtgcata tgaagcagca actgccactg agtacacgca ttcttttagg tctgagcgac
     4921 acgttgcaac gtaccggccc gacattatta gcgacagtat ttattgtcgc tgtgggtttc
     4981 tggctctggt taaaacgcgg caataaccgc caccgttttc atgccatgtt actgcgcgtt
     5041 gcgctcatcg gcccgctgat ttgcgccatt aacagcgcac gctatctccg cactttaagt
     5101 attttgcaat ccagcggcgt ccctctgctg gatgggatga atttgtccac cgaaagcctc
     5161 aacaacctcg aaattcgcca gcgcctggca aatgcggcag aaaacgttcg ccagggtaac
     5221 agcattcatc tttcactgga acaaaccgca attttcccgc cgatgatgct ctacatggtg
     5281 gcctctggcg aaaaaagcgg gcaactcggc acgttaatgg tcagagccgc agataaccag
     5341 gagacactcc aacaaaatcg gatcgcctta acgctctcca tcttcgagcc agcactcatt
     5401 attacgatgg cactgatcgt cctgtttatt gtcgtgtcgg tactccaacc tcttcttcaa
     5461 cttaactcaa tgattaatta aggaaatcat atgcgcgcaa cggataagca acgcggtttt
     5521 acattactgg aaattatggt ggtaattgtc atcattggcg tactcgccag cctggtggtt
     5581 cccaacctga tgggcaataa agaaaaggcg gataaacaaa aagccgtcag cgatattgtg
     5641 gcgctggaaa acgccctgga tatgtacaag ctcgacaatc atcgctatcc aaccacaaat
     5701 caggggcttg aatccttagt agaagcgccg acactgccac cgctggccgc aaactataac
     5761 aaggaaggtt atatcaagcg tctgcctgcc gatccctggg gcaatgatta tgtcctcgtt
     5821 aatcctggtg aacatggtgc atacgatctg ctttcagcag gacccgatgg tgaaatggga
     5881 accgaggacg acatcaccaa ctggggtttg agcaagaaga aaaagtaagt cagcgatgaa
     5941 tcagcaacgc gggtttaccc tgctggagat gatgctggtg ctggcgctgg tcgctatcac
     6001 ggcaagtgtg gtgctcttca catatggtcg ggaggatgcc gccagcactc gtgcgcgcga
     6061 aacagcggcg cggtttaccg ctgcacttga attagccatc gaccgcgcca cgctcagtgg
     6121 tcagcctgtc ggtatccatt tctctgattc agcatggcgc attatggtac cgggcaaaac
     6181 accatcagcc tggcgctggg ttccattaca agaagatgcc gcagacgaga gcaaaaatga
     6241 ctggggtgaa gaactctcaa ttcaacttca gccatttaaa cctgatgaca gcaaccaacc
     6301 gcaggtggtg attctggccg acggacaaat cacgcccttc tctttgttga tggctaatac
     6361 cgggaccggt gagccgctcc tgacgttagt cagttcaggc tcatggcccc tggatcaaac
     6421 gctcgccaga gatacccgcc catgaacaaa caatcaggga tgacactgct tgaagtctta
     6481 ctggcgatga gtattttcac cgctgttgcg ctgactttaa tgagcagtat gcaagggcaa
     6541 cgaactgcca tcgagcggat gcgtaacgag acgctggcat tgtggatagc ggataaccag
     6601 cttcagtcac aagattcatt cgacgaggaa aacacgtcca gttctggcaa agagttaata
     6661 aatggcgaag agtggaactg gcgcagcgat atccactcaa gcaaagacgg cacgcttctg
     6721 gaacgcacca taacggtgac attacccagc ggccagacaa cctcgcttac gcgctatcaa
     6781 agcatcaata ataaatccgg gcaggcacaa gatgattaat cgccagcagg gtttcacatt
     6841 gctggaagtc atggcggcgc tggcgatttt ctcaatgctt agcgtgctgg cgtttatgat
     6901 tttttctcaa gcttccgagt tgcatcaacg ttcacagaaa gaaatccagc agttcaatca
     6961 gctacagcgc accatcacca ttcttgataa cgatctcctg caactggtcg cccggcggaa
     7021 tcggagtacg gacaaaatca tggtgttggg tgaagaagcg atttttacca cgcaaagtcg
     7081 cgatccgctg gcccctctca gtgaagcaca aaccttactc actgttcact ggtatctgcg
     7141 aaatcatacg ctctaccgtg ctgttcgtac ttctgtggat ggcaggaagg atcaacccgc
     7201 ccaggcgatg ctggaacatg tcgagagctt tcttctggaa agtaacagcg gagaaagcca
     7261 ggagcttcct ctctcagtca cgttacatct gaagactcag caatatgggg cgttacagcg
     7321 ccgttttgca ttacctgagc agttagcgag agaagagtcg ccagctcaga cgcaggccgg
     7381 gaataataac catgaataat gaacaacgcg gcgtagcact gctcattgta ctcatgttac
     7441 tggcgctcat ggctgctctg gctgcagaca tgacgatcag ttttcacggc cagcttcatc
     7501 gaacccgcca ggtaaaccat catttgcaac ggcaatatga tattgagctg gcggagaaac
     7561 ttgcgcttgc cagcctcacc caggacgtta aagataacga cagacaaacc acgttgcagc
     7621 agtactgggc acaaccgcaa cagttgcagc tggaaaatgg caatacagtg aagtggcagt
     7681 tacgcgatgc ccagcactgt tttaatctca atgccttagc aaaaatctct gacgccccgc
     7741 tggcttcccc tgatttcccc gcccaggtat tcagtgccct gctgattaac gccggtatcg
     7801 atcgcggaaa caccgatgag atcgtgcaat caatcgctga ctatattgat gccgatgatt
     7861 cgccacgctt tcacggcgca gaagataact tttaccaaag ccaaacgccg cctcgccata
     7921 gcgccaatca aatgcttttt ctgaccggtg aattgcgtca gataaaaggc ataaccgaaa
     7981 acatctatca gcggcttatc ccgtatgtct gcgttctccc gacctcggaa cttagcatca
     8041 atcttaatat gctaacggag aacgatattc cgctcttcag agcattattc ctcaataaca
     8101 tcacggatgc tgacgctcgg gtcttattac aaaaaaggcc cagggaaggc tggctaacca
     8161 cagatgcatt tctttactgg gcgcagcagg atttctccgg cgtgaagccc ctggttgctc
     8221 aggtgaaagg gcatctcttt ccctatagcc gctattttac gctgagtacg gaaagtatca
     8281 gcgacgaaca atcccaggga tggcaaagcc atattttttt caaccgtaaa cagcagagcg
     8341 cccaaatcta tcggcgtacg ctgcaactct actaatcata aggatcgtga tgcctgaatc
     8401 gttgatggta atacgttctt tctcgacgct gcgtaagcat tgggaatgga tgacgttctc
     8461 cgcagatagc gtatcttcgg tacatacgct cacagacgat cttccgctgg ggtcgctggc
     8521 cgatcagccc ggtgccggaa atgttcacct tttgatccca cctgagggtc ttttatatcg
     8581 ttccctcacg ctgcccaacg ccaaatacaa actcaccgcg caaacattac agtggttggc
     8641 ggaggagaca ttacccgacg ccagccaaaa ttggcactgg acggttgtcg ataaacaaaa
     8701 cgaaagtgtc gaggtgatag gcattcagtc ggagaaactc agtcgttatc ttgagcgttt
     8761 acatactgcc ggactcaacg tgacgcgggt tttgccagat ggctgctatc ttccctggga
     8821 agtagatagc tggactctgg ttaaccagca aacaagctgg cttattcgca gtgccgcaca
     8881 tgccttcaac gaactggatg aacactggtt acagcatctt gctaaccagt ttccgcctga
     8941 gaatatgcgt tgttatggtg tagcgcctca cggcgttgca gcggccaatc cacttatcca
     9001 gcatcctgaa ataccatcac tgagtttgta ttctgccgat attgcattcc agcgctatga
     9061 catgctgcat ggtgtttttc gtaaacagaa aactgtaggc aaatcgggaa aatggctcac
     9121 ccgcctggca gtaagctgtc tcgttctcgc cattctttct tttgttggca gccggggcat
     9181 cgcgctctgg caaacgctta agattgaaga tcaacttcag caacaacagc aagaaacctg
     9241 gcaacgttat ttcccgcaga tcaaacacac ccacaacttt cgtttttact ttaagcagca
     9301 actcgctcag caatatcctg aagctgtacc gttgctctat catttacaaa cacttctgct
     9361 tgaacactct gaactgcagt taatggaggc gaactatagc cagaggcaaa agtcgctgac
     9421 cttaaaaatg agtgctaaga gtgaagccaa tatcgatcgt ttctgtgagt taacacagtc
     9481 ctggcttccg atggaaaaaa cagaaaaaga tccggtcagt ggtgtatgga cagtaaggaa
     9541 ctcagggaaa tgattaaatc atggtgggca gaaaaatcca catcggaaaa acagatcatt
     9601 gcggcactgg cggttctctc gctcggcgtt ttttgttggc ttgcggtgat aaaaccgata
     9661 gatacctaca ttgaagagca tcagtcccac gcgcaaaaaa ttaagaagga catcaaatgg
     9721 atgcaggatc aagcgagcac ccatggttta ctcggtcatc cagcgcttac gcagcccatc
     9781 aaaaatatcc ttctcgaaga agcaaaacgt gagaatttga ctatcacgct ggaaaacggt
     9841 ccggacaata ctctgacaat taatcctgtc acagctcccc tcgaaaacgt ctcccgctgg
     9901 ctcactacgg cacagataac atacggtatt gttattgaag accttcagtt tactcttgcc
     9961 ggaaacgaag agatcaccct caagcatttg tccttcaggg agcaacaata atgacaatgt
    10021 tactgccgct cttcattctg gttggtttta ttgcaggtta ttttgttaat gccatggcct
    10081 atcacctctc gcctttggag gataaaacgg cgttaacgtt tcgccaggta ttggttcatt
    10141 tctggcaaaa aaaatatgcc tggcatgata cagtgcccct gatactttgc gttgctgctg
    10201 ctatcgcctg cgccctggca cctttcacgc ccatcgtgac tggcgcactc tttctctatt
    10261 tctgtttcgc actcacgctc agtgttattg attttcgcac tcagctcctg cccgacaaac
    10321 tcaccttacc gctgctctgg cttggtattt aatgcgcagt ctggattaat tgatttacat
    10381 gatgcggttt acggcgcggt cgctggctat ggggtgctgt ggtgtgttta ctggggcgtc
    10441 tggttagttt gtcacaaaga gggattgggc tacggtgatt tcaagctact ggccgctgca
    10501 ggcgcgtggt gtggctggca aacgttgcca atgatactgc tgattgcctc gctgggtggc
    10561 attggttacg ccatcgtttc acaacttctg caacgccgga ctataaccac tatcgcattc
    10621 ggcccgtggc ttgcgctcgg cagcatgata aacctgggat atctggcctg gatctcttat
    10681 taaccgggag ggttctccct cccgacacgg ctcaaccttc ttcgcgaatc tgtgcttgca
    10741 gataattttg cagtcccatc ttctgaatca gatcaagttc cgtttccagc cagtcgatat
    10801 ggccttcttc atcgcgcaaa atttctatca tcatatcgcg gctgacgtaa tcatgaacgc
    10861 tatcggcata accaattgcc tcacgcaaat tcttcgcgcc atccagctca agtgccagat
    10921 cagaacgcag catttcctca acatcttcac caatgttcag tttgcccagg tcctgtaagt
    10981 ttggaagacc ttccagaaaa agaatgcgct ctatataacg atcggcgtgt ttcatctcat
    11041 caatggattc atgatactcc acatcattga gacgtttgag accccagttt ttaaacatcc
    11101 gggcatgaag aaagtactga ttgattgcga caagctcatt tcccaacagt ttgttgagat
    11161 aatttataac tttagtatca cctttcattt tttgactcct tcgcttccac tctttgaagc
    11221 gtagaacggc ttacgagtaa gtcaaaaaac acactccgtt tatgcggact ccttaaactc
    11281 cggcagttgc attaattcat cctccatcac ttcacgcgcg gcccggacac atttaccgca
    11341 ctgattgccg accggaatga atttttttaa ttgctggaac gagtgggggg aaaactggcg
    11401 cacagcctga cgaatttttt tatcgctgat accattacaa agacaaacgt acatagagac
    11461 tcccgtatac tttcttcaaa agtaaatgaa aatagttctt atttcaattg caggaagact
    11521 cttttttaag caaagaatag aaatatgaat aaaaataatg ggctaccaaa agtagcccat
    11581 tgacaaaaaa tgcggcgata ccggaaggta tcgccaacac atttattgct tagtaaacgg
    11641 cgcgaagatt tcgctaaatg cgtacttcgg agcctgttct ttagtcagac cgtggaattc
    11701 cggagacagg ttagtgccgc ccggcaggtc gcgcgcgatt gaccagatac caaccatacc
    11761 gagattacgc ttctgcgcat cctgcatgac cagacgagca tcagagagat agaacacctc
    11821 accctgaacg tcgttcacgc caaccatcgg cgtggtaccc atcatggcgt caatttctgc
    11881 atcactctta ttgccataga ggcctttcag ctgcgcatgc aggttggcaa tcgcagacgt
    11941 tgcacactta ccgtggatgt tttggccttc ggtgtttgca gactgacaaa tagcgttacc
    12001 gtagtccatt gtcatcacgt tcacacccgc cagctcaaca cctttcgctt tggcatcgct
    12061 caggacattc atcccttccg gcgtcaggcc tgtcggcaga attggcaagg tataccagat
    12121 agcaatatct ttgccttctg acttccattt atcctgcact ttcttcacag caaggttacg
    12181 acgttcaata gatgcctgat ccgcaaccca ggtgccttcg atatcgaagt ccaggactct
    12241 gaggttcagg ttatcaacga tgtcataata atgctgcatt agatcgtcaa cgttcttaca
    12301 ggaagctgcc agcggggcat tattagcacc accgatagac agcatcacat caccgccagc
    12361 ctcacgcagc gctttgattt tgctgtactg agcgtaattc tgcataccgt aagcggtccc
    12421 ccatgtcggc agacaggtgt tcgcatcttt actcaccaca aacgccagcg tgaagtggtt
    12481 gacgttatga ttcttagcca gcgcagccag atccgggatc gtattcagcg taaagtcgac
    12541 atacggtgca taaacgtgtt tcggccacgc tttcttcggc gtacctacgc gctctttggt
    12601 tccggtccag tcaacaaaga cacgccacgg gttgctgtca gaaggagaaa ctttctgcac
    12661 tttactctga gaaatgtagt tctcaccgtt aaagcgaatc agcgtatcac tggcataaag
    12721 cgtttctgga ttaaactgcg gcgcattatt cagctcttcg ttgctatagc tctgagtctt
    12781 acctaacggc ttccacgggc gactattgct accggtggcg ttttggttcg caaccagagc
    12841 agggttgtca ctttgcgtcc agaacagcgc ttcataagcc tgcccatcaa caacaacgcg
    12901 atcacctttc acgtacacgg tggaagcgga ccatgctttc gccggttcgt atttcttcca
    12961 cgggttatcg ccgccgggga caaagcccca tgcgtcttga tcgacagagg ttttataatg
    13021 tgcatcgtta taatctacga tgctgttcgc gctatacgct ttgctggcct ggaaaccatc
    13081 cacaataatg acgccgccat tatcaatttc acaggtagtc gggttaccgt actgactcat
    13141 ttccgcagcg gtagctgtac gcacgagacg ccatgggtta ttggagtttt ctacactggt
    13201 gccacgcggg caatcttcag aaccaaccca ccaggcattc tgataaacat taccattgaa
    13261 gataacatgg taaatttcgc tgccttcctg gccactccac gcctgcagtg agtaatcgtt
    13321 actgctatcc gctggtgttg atggctcgtt gttatccgga gttggagtaa ctggagtttc
    13381 cggtgtttcc ggagttggat caaccggagt cacagcaccg ccattattat ccggcttaac
    13441 ggaacaggag cctgggttac catactgagt gatttctgtt gccgttgccg cgcgaacata
    13501 acgccatggg ttgctggcat cgttttcttt cgcatcgcct gggcaatttg ccgcgcctac
    13561 ccaccaggcg ttcttataaa tgctgccgtt gtagataacg taccatgtag aagaaccttc
    13621 ctgacctttc caggctacaa cagcatagtt gtcgtttgac ttatcagctg gggctggctg
    13681 aacatcaggg gccggtttaa cgtccggtgc cggtttcaca tccggtgcag gctgtggtgc
    13741 tgaagtacaa gactgtggat tactggtttc tgagatttcc gttgccgtag cggcacgaac
    13801 ataacgccat gggttgctgg catcattgcc tttcgcatca cccgggcagt tagaagaggc
    13861 tacccaccag gcatttttat ataccgcacc attaaagacg acataccagg tttgaccgcc
    13921 ctgctgttta ttccaggcaa ctacagaaga attagacgga acagtgccct gtgctggtgt
    13981 agccgaaccg ccattagcgg gcgtattaga tgctggcgta tttgaagttg aagaagatga
    14041 gcttccgctc ttttcgcagg aaagtgtatt gccaaactga ctaatttcag cagctgttgc
    14101 ggtacgcttt aaacgccacg ggttagttgc atcatttgct ttcgcttttc ccgggcaatt
    14161 tgtagaagaa acccaccagg cattttcata aattttgcca tcga
//
LOCUS       DAFGPF010000121        14104 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFGPF010000121 DAFGPF010000000
VERSION     DAFGPF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14104
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.121"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(269..1918)
                     /gene="pgi"
                     /locus_tag="LSX49_004142"
     CDS             complement(269..1918)
                     /gene="pgi"
                     /locus_tag="LSX49_004142"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBL7170476.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            2443..3792
                     /gene="lysC"
                     /locus_tag="LSX49_004143"
     CDS             2443..3792
                     /gene="lysC"
                     /locus_tag="LSX49_004143"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HBL7170477.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDVA
                     ALAELAALQLLPRLNEGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHFNLFE"
     gene            4045..4317
                     /locus_tag="LSX49_004144"
     CDS             4045..4317
                     /locus_tag="LSX49_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HBL7170478.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKK
                     EYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSWSANTSTRGRR"
     gene            complement(4318..5190)
                     /gene="rluF"
                     /locus_tag="LSX49_004145"
     CDS             complement(4318..5190)
                     /gene="rluF"
                     /locus_tag="LSX49_004145"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HBL7170479.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKSGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            5538..6485
                     /locus_tag="LSX49_004146"
     CDS             5538..6485
                     /locus_tag="LSX49_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBL7170480.1"
                     /translation="MENSDDIRLIVKIAQLYYEQDMTQAQIARELGIYRTTISRLLKR
                     GRDQGIVTIAINYDYNENLWLEQQVKQKFGLKDVVVVSGNDEDEDTQLAMMGLHGAQL
                     LDRLLEPGDIVGFSWGRAVSALVENLPQAGQSRQLICVPIIGGPSGKLESRYHVNTLT
                     YSAAAKLKGESHLADFPALLDNPLIRNGIMQSQHFKTISAYWDNLDVALVGIGSPAIR
                     DGANWHAFYGGEESDDLNARQVAGDICSRFFDIHGAMVETNMSEKTLSIEMNKLKQAR
                     YSIGIAMSEEKYSGIVGALRGKYINCLVTNSSTAELLLK"
     gene            6555..7361
                     /locus_tag="LSX49_004147"
     CDS             6555..7361
                     /locus_tag="LSX49_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7170481.1"
                     /translation="MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGG
                     DGQYESHKGYQFWPTDISSAKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAP
                     AGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC
                     YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQ
                     LREGYTKNAIPIGRAGRLAEVADFVCYLLSERASYITGVTTNIAGGKTRG"
     gene            7371..7778
                     /locus_tag="LSX49_004148"
     CDS             7371..7778
                     /locus_tag="LSX49_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIA"
                     /protein_id="HBL7170482.1"
                     /translation="MVNAIFCAHGKLACAMLESVQMVYGDARVEAVEFVPGENAGDIV
                     AKLEKLVSIHNQDEWLIAVDLQCGSPWNAAAMLAMRNPRLRVISGLSLPLALELVDNQ
                     DSMNVDELCEHLTQIAKQTCVVWRQVATAEEDF"
     gene            7778..8272
                     /locus_tag="LSX49_004149"
     CDS             7778..8272
                     /locus_tag="LSX49_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HBL7170483.1"
                     /translation="MNITLARIDDRLIHGQVTTVWSKVANAQRIIICNDEVYNDEVRR
                     TLLRQAAPPGMKVNVVNIEKAVAVYHNPQYQDETVFYLFTRPQDALAMVRQGVKIGTL
                     NIGGMAWRPGKKQLTKAVSLDDDDINAFHELNNLGVILDLRVVASDPSINIIDKINEQ
                     LIAN"
     gene            8338..9135
                     /locus_tag="LSX49_004150"
     CDS             8338..9135
                     /locus_tag="LSX49_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBL7170484.1"
                     /translation="MEISTLQIIAIFLFSCIAGMGSVLDEFQTHRPLIACTVIGLILG
                     DLKTGIMLGGTLELIALGWMNVGAAQSPDSALASIISAILVIVGQQSIATGIAIALPV
                     AAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDILHVSALGVQALRVAIPALIVSL
                     FVSADMVSNMLSAIPEFVTRGLQIAGGFIVVVGYAMVLRMMGVKYLMPFFFLGFLAGG
                     YLDLSLLAFGGVGVIMALLYIQLNPQWRKAEPHPQTTTITALDQLDD"
     gene            9146..9970
                     /locus_tag="LSX49_004151"
     CDS             9146..9970
                     /locus_tag="LSX49_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL7170485.1"
                     /translation="MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIK
                     RLYPLKEDQVAALRRHLVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVG
                     LMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNVVRLAMKWYGLQL
                     GFRKGVNIVSDMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGAT
                     VTITVQNILDQLCPGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS"
     gene            10022..11251
                     /gene="sorE"
                     /locus_tag="LSX49_004152"
     CDS             10022..11251
                     /gene="sorE"
                     /locus_tag="LSX49_004152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-sorbose 1-phosphate reductase"
                     /protein_id="HBL7170486.1"
                     /translation="MKTTALRLYGKRDLRLETFDLPEMQEDEILATVVTDSLCLSSWK
                     EANLGENHKKVPDDVATNPIIIGHEFCGDILAVGKKWQHKFQPGQRYVIQANLQLPDR
                     PDCPGYSFPWVGGEATHVVIPNEVMEQDCLLAYDGETYFEGSLVEPLSCVIGAFNANY
                     HLQEGSYNHTMGIRPQGRTLILGGTGPMGLLAIDYALHGPVNPSLLVITDTDNDKLSY
                     ARKHYPSEPQTLIHYLNAADAAFDTLMALSGGHGFDDIFVFVPNEGLVTLASSLLATD
                     GCLNFFAGPQDKHFSAPINFYDVHYAFTHYVGTSGGNTDDMRAAVKLIEEKKVQAAKV
                     VTHILGLNAAGETTLELPAVGGGKKLVYTGKYLPLTSLTQIQDQALAAILARHQGIWS
                     GEAEQYLLAHAEAISHD"
     gene            11633..12322
                     /gene="pepE"
                     /locus_tag="LSX49_004153"
     CDS             11633..12322
                     /gene="pepE"
                     /locus_tag="LSX49_004153"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HBL7170487.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIIDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(12412..14043)
                     /locus_tag="LSX49_004154"
     CDS             complement(12412..14043)
                     /locus_tag="LSX49_004154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBL7170488.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLPLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
BASE COUNT         3399 a         3568 c         3712 g         3425 t
ORIGIN      
        1 ccacgattaa aaatttattt taggattaac ctcacggtat gattttcgtt aaatgacaga
       61 caagaggatt tatctgataa aacaatgccg acttatagtc ggcattgttt ttaaggctat
      121 ttaatcaatc gtactatgta ttaattgccg aatacgatgt acatatcggc atcgacctgt
      181 aggcctgata agacgcgacc gcgtcgcatc aggcatcggt tgccggatgc ggcgtgaacg
      241 ccttatccgg cctacatatc gacaatgatt aaccgcgcca cgctttatag cggttaatca
      301 gaccattggt cgagctatcg tggctgctga tttctttgtc atctttcagc tctggcagaa
      361 tacggttcgc cagttgttta cccagctcca cgccccattg gtcgaaggtg aagatgttca
      421 ggatcacgcc ctgagtaaag attttgtgct catacagcgc aatcaacgcc cccaggctga
      481 acggagtgat ttcacgcagc aggatggagt tggtcgggcg gttaccttcg aacactttga
      541 acggcaccac gtagtcaagc gttgccggat ctttaccctg atcgcgatat tcctgctcaa
      601 ccacttcgcg ggatttacca aacgccagcg cttcggtctg agcaaagaag ttagacagca
      661 gtttctggtg atgatcagag agcgggttat gggtgatagc cggagcgatg aaatcgcacg
      721 gtaccatttt ggttccctgg tggatcagct gatagaacgc gtgctgaccg ttcgtgccag
      781 gttcacccca gataatcggg ccagtctggt aatccacaac cttaccgtta cggtcaacat
      841 acttaccgtt ggattccata ttgccctgct ggaagtacgc cgcgaaacgg tgcatatact
      901 ggtcatacgg cagaatcgct tcagtttccg cgccaaagaa attgttgtac cagatgccaa
      961 tcagcgccag cagtacaggc aggtttttct cggcaggcgt ggtggagaaa tgcttgtcca
     1021 tcgcgtgtgc gccagaaagc agttcaacga agttatcaaa gccgatggag agaacaatcg
     1081 acaggccaat cgctgaccac aaagaataac gaccgccgac ccagtcccag aattcgaaca
     1141 tgttggcagt atcaatacca aactcgccaa cggctttggc gttggtggaa agcgccgcaa
     1201 agtgtttcgc aacgtgcttc tcatcacctg ccgctttcag gaaccagtca cgcgcgctat
     1261 gggcgttggt catggtttcc tgagtggtga aggttttaga tgctaccagg aacagcgtgg
     1321 tttccgggtt tacttttttc agcacttccg cgatgtgagt cccatcgacg ttagaaacaa
     1381 agtgcatgtt caggtggttt ttgtatggac gcagtgcttc agtcaccatg tacgggccga
     1441 ggtcagaacc gccgatcccg atgttcacta cgtcagtgat tgccttgccg gtatagcctt
     1501 tccactcacc ggaaataatc gcttccgaga aggttttcat cttctccagc accgcgttga
     1561 cttccggcat aacatctttg ccatcaacca gaatcggggt attgctacgg ttacgcagcg
     1621 ctacgtgcag tacggcgcgg ttttcagtgc ggttgatctt ctcgccagag aacatcgact
     1681 taatcgcgcc cgccagatcg cactctttcg ccagatcttg taatttcgcc agcgtctctt
     1741 cagtgatgcg gtttttggag taatccacca gcatctgatc gtcgaaggtt gcggagaact
     1801 tagaaaaacg atcgccgtct ttagcaaaaa gatcggcgat cgtaacgtct ttcatttcat
     1861 cgaagtgttt ctgtagtgcc tgccaggcag cggtctgcgt tggattgatg tttttcatta
     1921 gcaatactct tctgattttg agaattgtga ctttggaaga ttgtagcgcc agtcacagaa
     1981 aaatgtgatg gttttagtgc cgttagcgta atgttgagtg taaaccctta gcgcagcgaa
     2041 gcatttatta gctgaactac tgaccgccag gtgtggatga aaaatccgca tgaccccacc
     2101 gttgacaacc gccccgctca ccctttattt ataaatgtac tacctgcgct agcgcaggcc
     2161 agaagaggcg cgttgcccaa gtaacggtgt tggaggagcc agtcctgtga taacacctga
     2221 gggggtgcat cgccgaggtg attgaacggc tggctacgtt catcatcggc tacaggggct
     2281 gaatcccctg ggttgtcacc agaagcgttc gcagtcgggc gtttcgcaag tggtggagca
     2341 cttctgggtg aaaatagtag cgaagtatcg ctctgcgccc acccgtcttc cgctcttccc
     2401 ttgtgccaag gctgaaaatg gatcccctga cacgaggtag ttatgtctga aattgttgtc
     2461 tccaaatttg gcggtaccag cgtagctgat tttgacgcca tgaaccgcag cgctgatatt
     2521 gtgctttctg atgccaacgt acgtttagtt gtcctctcgg cttctgctgg tatcactaat
     2581 ctactggtcg ctttagctga aggactggaa cctggcgagc gattcgaaaa actcgacgca
     2641 atccgcaata tccagtttgc cattctggaa cgtctgcgtt acccgaacgt tatccgtgaa
     2701 gagattgaac gcctgctgga gaacattacc gttctggcag aagcggcggc gctggcaacg
     2761 tctccggccc tgacagatga actggtcagc cacggcgagc tgatgtcgac cctgctgttt
     2821 gtcgagatcc tgcgcgaacg cgatgttcag gcacagtggt ttgatgtacg taaagtgatg
     2881 cgtaccaacg accgatttgg tcgtgcagag ccagatgtag ccgcgctggc ggaactggcc
     2941 gcgctgcagc tgctcccacg cctcaatgaa ggcttagtga tcacccaggg atttatcggc
     3001 agcgaaaata aaggtcgtac aacgacgctt ggccgtggag gcagcgatta tacggcagcc
     3061 ttgctggcgg aggctttaca cgcatctcgt gttgatatct ggaccgacgt cccgggcatc
     3121 tacaccaccg atccacgcgt ggtttctgca gcaaaacgca ttgatgaaat cgcgtttgcc
     3181 gaagcggcag agatggcaac ttttggtgca aaagtactgc atccggcaac gttgctaccc
     3241 gcagtacgca gcgatatccc ggtctttgtc ggctccagca aagacccacg cgcaggtggt
     3301 acgctggtgt gcaataaaac tgaaaatccg ccgctgttcc gcgcgctggc gcttcgtcgc
     3361 aatcagactc tgctcacttt gcacagcctg aatatgctgc attctcgcgg tttcctcgcg
     3421 gaagttttcg gcatcctcgc gcggcataat atttcggtag acttaatcac cacatcagaa
     3481 gtgagcgtgg cattaaccct tgataccacc ggttcaacct ccactggcga tacgttgctg
     3541 acgcaatccc tgctgatgga gctttccgca ctgtgccggg tggaagtgga agagggtctg
     3601 gcgctggtcg cgttgattgg caatgacctg tcaaaagcct gcggcgttgg caaagaggta
     3661 ttcggcgtac tggaaccgtt caacattcgc atgatttgtt acggcgcatc cagccataac
     3721 ctgtgcttcc tggtgcccgg cgaagatgcc gagcaggtgg tgcagaagct acattttaat
     3781 ttgtttgagt aaacacagta tggcccggaa gacattattt cgggccgtat tgtttttctt
     3841 gtcattatgc ccataaataa acgagcctgt actctgttaa ccagcgtctt tatcggagaa
     3901 taattgcctt taatttttta tccgcatctc taactaatta tcgaaagaga taaatagtta
     3961 agagaaggca aaatgaatat tatcagttct gctcgcaaac gaattcccgt acactgaact
     4021 ctctggctca ctgagggcac catcatggca ctcccccgta ttacccaaaa agagatgact
     4081 gaacgcgagc agcgtgaact taaaacactg ctggatcggg cgcggattgc gcatggtcgc
     4141 gtactgacca actccgaaac caacagcatt aagaaagagt acatcgataa attaatggtc
     4201 gagcgtgagg ctgaagcgaa aaaagcccgc caattgaaga aaaagcaggc ttataaaccg
     4261 gatcctgagg cgtcatttag ctggtcagca aatacgtcga cgcgcggcag gcgctgatta
     4321 acgccccttc tttttgcgcc ccggcgaggt aaaacgctta ccgttggacg ccgggcgacc
     4381 gcctttttcc gccgtttttt ccatcttaac gactggacgt ttgatgccta ccgttttcgg
     4441 tttggccttc gctttaggtt ttgcctcgga agaggaattt tcaatgagct taaagagatc
     4501 gattaactca tcgtcggtta aatcgcgcca ctcacccagc ggaatgccgc ttaagctgac
     4561 gttcataatg cgcgtacgtt ccagcttttt cacttcgtaa ccaaagtgct cgcacatgcg
     4621 acgaatctga cggttcagcc cctgcaccag ggtaatgcgg aagacaaacg gtgcttcttt
     4681 tttgactttg cactttttag ttaccgtccc gaggatcggc actcccgccc ccataccacg
     4741 aataaattca tcggtaatcg gtttatcaac cgtcaccaga tactctttct catgatcgtt
     4801 acccgcacgg aggatcttat tcactagatc gccgtgattg gtgaggaaaa tcagcccctg
     4861 ggaatcttta tccaggcggc caatcgggaa cacgcgtttg ctgtggttaa cgaaatcgac
     4921 aatgttatcg cgctcgccat cttcggtggt gctgacaatg cctacgggct tgttcagggc
     4981 gataagtacc aaatcttcgg cttcccgagg ctcaatcaac tgaccgttta ctttcacaac
     5041 gtcgccggat ttcacctgat cgccaatggt ggctcgcttg ccattaagga acacattgcc
     5101 ttgctcgata tagcgatccg cttcgcggcg tgagcaaatt ccgctttcgc tgatgtattt
     5161 atttaaacgg actgatgagt cgggcagcat aaattctcct gtaaaacgcg gaatataccg
     5221 tacctcttag cggggaaaaa cagggttatg cggcaacgtc gaaattaaat gtgatctgcc
     5281 acgcctttta tcacaaaagt gtctccggaa gtacgatgca aatttgcctg gcaaaataag
     5341 gataatcaac aaattacgaa tcgctgcaca cctgtgctga tgactactac gcagagaaac
     5401 aaatgtgcaa gagaaagcgc tatttccccc catgcaaaga gtgaaaaatc gctttgaaag
     5461 gccatcatga tggggttata tcagatcaag cggtgagaaa gcgtatttgc acaaatgtgc
     5521 agaaccagga ggcggcaatg gaaaacagtg acgatatccg tttgattgtg aagattgccc
     5581 aactctatta cgaacaggat atgacgcagg cgcaaattgc gcgcgaactg ggtatttacc
     5641 gcaccaccat cagccgcttg cttaaacgag gccgcgatca gggaattgtc accatcgcca
     5701 tcaactatga ctacaacgaa aatctctggc tggagcagca agtgaagcaa aagtttggcc
     5761 tgaaagacgt tgtggtggtg tcaggaaatg atgaggatga agatactcaa ctggcgatga
     5821 tggggttaca cggcgcgcaa ctgctggatc gcttgctgga acctggtgat attgttggtt
     5881 tttcctgggg tcgcgcggtg agcgcactgg ttgaaaactt gccgcaggcg gggcaatcgc
     5941 ggcagttaat ttgcgtgccg attattggcg gcccgtccgg taaactcgaa agccgctatc
     6001 acgtaaacac attaacctac agcgcggcag cgaagctgaa aggggaatcg catctcgcgg
     6061 attttccggc tctgctggat aacccattaa ttcgtaatgg gatcatgcag tctcagcact
     6121 ttaaaaccat ctctgcctac tgggataatc tggatgtcgc cctggtggga attggctcac
     6181 cggccattcg cgacggcgct aactggcatg cgttttatgg tggtgaagag agtgacgacc
     6241 tgaatgcccg ccaggttgct ggcgatattt gctcgcgctt ttttgatatt cacggcgcaa
     6301 tggttgaaac gaatatgagc gaaaaaacac tctctatcga aatgaataaa ttaaagcagg
     6361 cacggtattc cattggcatt gccatgagcg aagaaaaata cagcggaatt gttggtgcac
     6421 tgcgtggaaa atatattaat tgtctggtaa cgaatagcag cacagctgaa ctattactga
     6481 aataaaaatc ttcccgatgt ttaccgtaat aaaaattacg gcgggtcctt attatctaaa
     6541 atcaggagtc tgttatgcaa acgtggttaa atttgcagga taaaatcatt attgtcaccg
     6601 gtggcgcatc cggcattggt ctggcgattg tggatgaatt attagcacaa ggcgcgaatg
     6661 tacagatggt cgatattcac ggtggcgatg gtcagtatga aagccataaa ggttatcagt
     6721 tctggccgac cgatatttcc agcgccaaag aggtaaatca tacggtagca gaaattatcc
     6781 agcgttttgg tcgcatcgac ggtctggtta acaacgccgg ggtcaatttc ccgcgtctgc
     6841 tggtcgatga gaaagcgcct gccgggcagt atgaactcaa cgaagctgca ttcgaaaaaa
     6901 tggtcaatat caaccagaaa ggcgtttttc tgatgtcgca ggcggtggcg cgacagatgg
     6961 tcaaacaaca tgatggcgtg attgtgaatg tttcctcaga aagtgggctg gaaggctcag
     7021 aaggccaaag ctgttacgcc gcgaccaaag ccgcgctcaa tagcttcacg cgctcctggt
     7081 cgaaagagct gggtaagcac ggtatccgtg tggtcggtat cgcgccgggg attctggaaa
     7141 aaacagggct gcgcacgccg gaatatgaag aggcgctggc gtggacgcgc aatatcaccg
     7201 tcgagcagct gcgtgaaggc tataccaaaa acgccattcc tattgggcgc gccggaagat
     7261 tagcagaagt ggctgatttt gtttgttatc tgctgtctga acgcgccagc tatatcaccg
     7321 gagtaaccac taacattgcg ggcggcaaaa cgcgcggcta aggaggcttt atggtcaatg
     7381 ccattttttg tgcgcatggc aaattagctt gcgccatgct ggaatcggtt cagatggttt
     7441 acggcgatgc cagggtcgag gcagttgaat ttgtgcccgg cgagaacgcc ggagacatcg
     7501 tagcaaagct ggaaaagtta gtaagcattc acaatcaaga tgagtggctg attgccgtgg
     7561 atttacagtg cggcagcccg tggaatgcgg cagcgatgct tgcgatgcgc aatcctcgtc
     7621 tgcgggtaat cagcggcctt tctctgccgc tagcgctcga actggttgat aaccaggaca
     7681 gcatgaatgt tgatgaactg tgtgaacacc tgacgcaaat cgcaaagcaa acctgcgtcg
     7741 tctggagaca ggtggcaaca gcggaggagg atttctgatg aacattacgc tcgcccgcat
     7801 tgatgaccgc ctgatccacg gccaggtcac taccgtctgg tctaaagtgg ctaacgccca
     7861 gcgcattatt atctgcaatg acgaagttta taacgatgaa gttcgccgga cattattgcg
     7921 tcaggctgcg ccaccgggaa tgaaggttaa cgtggtcaat attgaaaaag ccgtcgcggt
     7981 gtatcacaac ccgcaatatc aggacgaaac cgttttttat cttttcactc gcccacagga
     8041 tgccttagca atggttcgcc agggggtaaa aataggtacc ctgaatattg gcggcatggc
     8101 ctggcgtcct ggtaaaaaac agttaaccaa agcagtttca ttagatgacg atgatattaa
     8161 cgcatttcat gagttaaata atcttggcgt catactggat ttacgcgtcg tagcgtcaga
     8221 tccctcaatc aatattatcg acaaaataaa tgaacagtta atcgcgaatt aaataatagc
     8281 gcctgtgtac atatgcttta acaggcaggg atgacgacac ttaaaaggtg acaaatcatg
     8341 gaaataagta ctctacaaat cattgctata tttctttttt cctgtattgc cggaatgggc
     8401 agcgtgctgg atgaatttca gactcatcgt ccgttaattg cctgtacggt gattggttta
     8461 attctcggtg atttaaaaac cggaattatg ctcggtggta cgctggaatt gatagctctc
     8521 ggctggatga acgtcggcgc ggcgcaatct ccggattctg cgctcgccag cataatctcc
     8581 gccattctgg ttatcgttgg tcagcaaagc atcgccaccg gaatcgccat cgcgttgcct
     8641 gtggctgcgg caggccaggt gctgacggtg tttgcccgta ccatcaccgt agtgttccag
     8701 cacgcggcgg ataaagcagc ggaagaagca cggtttcgca ctctcgatat tctgcatgtc
     8761 tccgcgcttg gcgtgcaggc actgcgcgtt gctattccgg cactgattgt ctcgctgttc
     8821 gtcagcgctg atatggtgag caatatgctg agcgccattc ccgaatttgt gacccgtgga
     8881 ctgcagattg ctggcggttt tatcgtggtg gtcggttacg ccatggtgct tcgcatgatg
     8941 ggcgtgaaat atttgatgcc tttctttttc ctcggtttcc tcgcaggtgg ctacctcgat
     9001 ctcagtctgc tggcgttcgg tggcgtcggc gtgatcatgg ccctgctcta catccagtta
     9061 aatccacagt ggcgtaaagc tgaaccacat ccccagacca ccactatcac cgcccttgac
     9121 caacttgatg attaacggag ccatcatgga acagagaaaa attacacgca gcgatctggt
     9181 gagcatgttt ctgcgctcca acctgcaaca ggcatccttt aactttgaac gtattcacgg
     9241 gctgggtttt tgctacgaca tgatccccgc catcaaacga ctttacccat taaaagagga
     9301 tcaggttgcg gcgctcaggc gacacctggt gttcttcaat accacgccag ccgtatgtgg
     9361 cccggtcatc ggcgtcactg ccgccatgga agaggcgcga gccaacggcg cggaaattga
     9421 tgacggtacc attaacggca tcaaagtcgg tctgatggga ccattggcag gagttggcga
     9481 tccactggtc tggggaacgc tgcgcccgat taccgccgcg ctcggcgcat ctctggcact
     9541 ttcgggcaac attctcggcc ccctgctgtt cttctttatt ttcaacgtgg tgcgcctggc
     9601 gatgaagtgg tatggcctac agctcggctt tcgcaaaggg gtgaatatcg tcagcgatat
     9661 gggcggtaat ttgctgcaaa aactcaccga aggcgcgtcg attctcgggc tgtttgtgat
     9721 gggcgtgctg gtgaccaaat ggacgtcaat caacgtaccg ttggtggttt cacaaacgcc
     9781 tgccgccgat ggtgccaccg tcaccataac cgtgcagaac atcctcgacc aactttgccc
     9841 tggtttgctg gcgctcggtc tgacgctgct gatggttcgt ctgctcaaca aaaaaattaa
     9901 cccggtatgg ctgattttcg ccctgtttgg tttagggatt atcggtaatg cgctgggctt
     9961 cctgtcctga ttcttcgccc cggcgcaacc gtcggggcca tcgttcaaca cgaggtggtt
    10021 tatgaaaaca acagctctgc gtctttatgg taaacgtgat ttacgcctgg aaacctttga
    10081 ccttcctgaa atgcaggagg atgaaatcct cgcaacggtg gtcactgaca gcctgtgcct
    10141 ctcttcctgg aaagaggcca atctgggtga aaatcataaa aaagtacccg acgatgtggc
    10201 gaccaatccc atcatcatcg gccacgaatt ttgcggcgat attctggccg tgggtaaaaa
    10261 gtggcagcac aaattccagc cgggtcagcg ttatgtgatt caggccaacc tgcaactccc
    10321 cgaccgcccg gattgccccg gctactcctt cccgtgggta ggcggcgaag cgacgcatgt
    10381 ggttattccc aacgaggtca tggaacaaga ttgcctgctg gcatacgacg gcgaaaccta
    10441 ttttgaaggc tcgctggttg aaccgctttc ctgcgtgatt ggcgcgttca acgccaacta
    10501 tcatcttcag gaaggtagtt ataaccacac gatggggatt cgcccgcaag ggcgcacgct
    10561 gatcctcggc ggcaccggac caatgggact gttggcgatt gattatgcgc tacatggacc
    10621 cgttaaccct tcgctgctcg tcattaccga taccgacaac gacaaattga gttatgcgcg
    10681 caagcactat ccatcagaac cgcaaacact gattcattat ctcaatgccg ccgatgcagc
    10741 atttgatacg ttaatggcac tgagtggcgg tcacggcttc gatgatattt tcgtctttgt
    10801 gcctaatgaa ggactggtga ctctcgcctc ttccttgctg gcgacagatg gttgtctgaa
    10861 tttcttcgcc ggaccgcagg ataagcactt cagcgcgcca attaatttct acgatgtgca
    10921 ttatgcattt acccactacg tgggcacgtc aggcggcaat accgacgaca tgcgcgcagc
    10981 ggtcaaatta attgaagaga aaaaagtgca ggccgcaaaa gtggtaacac atattcttgg
    11041 gctgaatgcc gcgggcgaaa ccacgcttga attgcctgcc gtcggcggcg gcaaaaagct
    11101 ggtgtatacc gggaaatacc tgccgctgac gtcactcacg cagattcagg atcaagcact
    11161 ggcggcgatt ctggcgcgtc atcaggggat ctggtccggt gaggcggagc aatacctgct
    11221 cgcccatgca gaggcaattt cccatgatta atcgcgctac ttaactctgc atgtcgctgg
    11281 ctggtcgccg cggcaacttc gcgacctgat gtgcggctga ttgctgaagc ggcacaatgt
    11341 gcacgagaag gataaaaaaa catcagcgcc ttaaggggcg ctcaaattgg tggcaaagtg
    11401 cacattgttt atgccggatg cggaatgaag ccttattcgg cctacataat cttgaaaatt
    11461 caatatattg cagttatctg gtaggccagg taagcgtagc gcatcaggca atcctgtgtt
    11521 tgtcatcagt ctcagcgcct gtgcaatatg tgacatcgtg agccatgtca gtaagtggtt
    11581 aaattcgcag tggtagcatt ccttccgtgt tttcttacta accggagaag taatggaact
    11641 gcttttattg agtaactcga cgctgccggg taaagcctgg ctggaacacg cgctgccgct
    11701 gattgctgaa cagttgcagg gtcgccgttc tgcggtattt attcctttcg ctggcgtaac
    11761 gcagacctgg gatgattaca cagcgaaaac ggctgcggtt ctcgctccgc tgggtgtttc
    11821 tgtcaccggt attcatagcg ttgtcgatcc cgttgccgcg attgaaaatg cggaaattgt
    11881 gattgtcggc ggcggtaata ctttccagtt gctgaaacag tgccgcgagc gcgggctgct
    11941 ggcacccatt actgacgtgg tgaaacgtgg cgcgctgtat attggctgga gcgcaggcgc
    12001 taaccttgct tgcccaacca ttcgtaccac caacgatatg ccgattatcg atccgcaagg
    12061 tttcgatgcg ctaaatctgt tcccgctaca aatcaacccg cacttcacca acgcgctgcc
    12121 ggaaggccat aaaggtgaaa cccgtgagca gcgtattcgc gaactgctgg tcgtcgcgcc
    12181 agaactgacg attattggtc tgccggaagg taactggatc acagtaagta aaggtcacgc
    12241 tacgctgggt ggcccgaaca ccacttatgt atttaaggct ggtgaagaag cggtgccgct
    12301 ggaagcgggt caccgttttt aagtgaattg ccggatgcat gatccggcat cttgttcata
    12361 gtgcctgatg caacgcttta cgcgtcttat caggccttca gggtcacggt attaatactc
    12421 gtcccgtcct tcatcttcat ccggctgttc cagcacactg taagccaccg aacaaaacag
    12481 cgagttcaga cgctgcatat ctcccagtaa gcctaaatgt agcgaactgg tttcaatact
    12541 ctgcacgttt tgctggtgca ggcgatcgac gtgggcgtgg gaatagcggc gattaagaat
    12601 gcgaaaacga tgtttgctgc ggcgcaaacg acgggcgctg gtaacatcgc cagagaagaa
    12661 aaccgacatt gccagtttta aattactgag caattgctca tagagcgcat ccagttcctt
    12721 caagccatca agcgaaaatg ctcgccttgc tgccagcgat ttgtcggcaa tttcgctgcc
    12781 catgcgctcg acgatatcgg aggcctgttc aaggttgagc gacatttcga tgatctccgc
    12841 ccagcggcgc gactcttctt ctgccagttc ctcttttggc atccgcgcca gatacagctt
    12901 aatggcggta tagagaacgt tgatgtcatc agccagctta cgcagctctt tctcctgccg
    12961 tggctcgccg tgcatcactt tattcagccc ttccatcatc tgttccatgg cgtcgccaat
    13021 gcgcagggtt tcgcgggcag cgttcgccag agcaagcgtg ggcgtatcca gcgcgctgac
    13081 atccagatgt ttaggccgta gctgggtatc cagttccggt tcatcgcgaa taatcgtttt
    13141 gcaaaaccgt gccatcgggt caacgaatgg caacatgacc aggcagcgta caaggttgta
    13201 gaagacgtgg aaatagatca ccaattccgc ttttggcaat ggcaacttcc ccattgtctc
    13261 tgccagcaaa tgaacaaacg gcaggataat caggctaccc accagcttaa acagcaggct
    13321 acccagcgcg acacggcggg ctgcggcatt ggcggcactg ttgttgagca tcgccagcag
    13381 gccggaaccg aggtttgcac caatcaccag acaaagcgcc actgggaaag agataatgcc
    13441 tgcggcggtc agagtcgcgg tcagcagtac cgcggcaagg ctggagtagc tgataatggc
    13501 gaacatcgca ccaatcagcg catccagcaa aatgtcgcca gtcagcgagg caaagatcac
    13561 ctgaacgccg tttgcctgag tgatcggcgt tacggcctgc acaatcaact ccagcgccag
    13621 taaaatcagc ccaagaccaa taccgacgcg gcccagttgc ccggcgcgtg actgtttgcg
    13681 tccgaggaaa aaaatcacgc cgataaaaat aagtaacggt gacagccagg ataaatcgaa
    13741 ggtgagaata cgcgccatca gcgccgtccc gacatctgca cccagcacaa tcaccagcgc
    13801 aggcgcgaga gcaaccagat cctgagcgac gaacgaggtc accagcatgg tggtggcatt
    13861 actgctctgc accagtgcgg taacgccgat ccccgcgcaa aaggcgagcg gctttttttc
    13921 gacgctccgg ctaaggacag tacgcagacg cgcgccgaag acgcgcatta cgcctgttcg
    13981 aacaatatgg gtcccccaga ccagcagggc gacggcagaa agcaggtgaa gcaaagttag
    14041 cacggaatca ggttctcctt tttgttatgc attttcctgt taagattttt ctaatcacgt
    14101 tgtt
//
LOCUS       DAFGPF010000122        14103 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFGPF010000122 DAFGPF010000000
VERSION     DAFGPF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14103
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.122"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(2..94)
                     /locus_tag="LSX49_004155"
     tRNA            complement(2..94)
                     /locus_tag="LSX49_004155"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ser,seq:gct)
     gene            complement(410..595)
                     /gene="csrA"
                     /locus_tag="LSX49_004156"
     CDS             complement(410..595)
                     /gene="csrA"
                     /locus_tag="LSX49_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBL7170489.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(830..3460)
                     /gene="alaS"
                     /locus_tag="LSX49_004157"
     CDS             complement(830..3460)
                     /gene="alaS"
                     /locus_tag="LSX49_004157"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBL7170490.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFDAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKSVDAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLAVGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(3589..4089)
                     /gene="recX"
                     /locus_tag="LSX49_004158"
     CDS             complement(3589..4089)
                     /gene="recX"
                     /locus_tag="LSX49_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBL7170491.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARICQELNQKGIS
                     REATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDI
                     WRNFAD"
     gene            complement(4158..5219)
                     /gene="recA"
                     /locus_tag="LSX49_004159"
     CDS             complement(4158..5219)
                     /gene="recA"
                     /locus_tag="LSX49_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBL7170492.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(5299..5796)
                     /gene="pncC"
                     /locus_tag="LSX49_004160"
     CDS             complement(5299..5796)
                     /gene="pncC"
                     /locus_tag="LSX49_004160"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HBL7170493.1"
                     /translation="MTESELMQLSEQVGLALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            5978..6217
                     /locus_tag="LSX49_004161"
     CDS             5978..6217
                     /locus_tag="LSX49_004161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170494.1"
                     /translation="MAIKKTDNTPQNVLKQTTQMRMWVIIGGISALISVICKVLSSGY
                     LEPFDFGQAALGVVCLGYAISLSKKIKQLRHSNKQ"
     gene            complement(6256..7341)
                     /gene="mltB"
                     /locus_tag="LSX49_004162"
     CDS             complement(6256..7341)
                     /gene="mltB"
                     /locus_tag="LSX49_004162"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HBL7170495.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETETTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTRYSISQLAAAGLTPQQSLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALARVQ"
     gene            7598..8161
                     /gene="srlA"
                     /locus_tag="LSX49_004163"
                     /gene_synonym="gutA"
     CDS             7598..8161
                     /gene="srlA"
                     /locus_tag="LSX49_004163"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBL7170496.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVRLAGATS"
     gene            8158..9117
                     /gene="srlE"
                     /locus_tag="LSX49_004164"
                     /gene_synonym="gutE"
     CDS             8158..9117
                     /gene="srlE"
                     /locus_tag="LSX49_004164"
                     /gene_synonym="gutE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBL7170497.1"
                     /translation="MTRIRIEKGTGGWGGPLELEATPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITVVGEATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSAVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            9128..9499
                     /gene="srlB"
                     /locus_tag="LSX49_004165"
                     /gene_synonym="gutB"
     CDS             9128..9499
                     /gene="srlB"
                     /locus_tag="LSX49_004165"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL7170498.1"
                     /translation="MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGALHPGLQFTLGRHRYPVTAVGSVAEDNLRELGHVTLRFDGLSEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            9503..10282
                     /gene="srlD"
                     /locus_tag="LSX49_004166"
     CDS             9503..10282
                     /gene="srlD"
                     /locus_tag="LSX49_004166"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBL7170499.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGEGTAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPEQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            10388..10747
                     /gene="gutM"
                     /locus_tag="LSX49_004167"
     CDS             10388..10747
                     /gene="gutM"
                     /locus_tag="LSX49_004167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBL7170500.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPH
                     DPLSQNALSLALKLKRG"
     gene            10814..11587
                     /gene="srlR"
                     /locus_tag="LSX49_004168"
                     /gene_synonym="gutR"
     CDS             10814..11587
                     /gene="srlR"
                     /locus_tag="LSX49_004168"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HBL7170501.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVGFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEEKGIDVIITGESNE"
     gene            11580..12545
                     /gene="gutQ"
                     /locus_tag="LSX49_004169"
     CDS             11580..12545
                     /gene="gutQ"
                     /locus_tag="LSX49_004169"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HBL7170502.1"
                     /translation="MSEALLNAGRQTLMLELQEASHLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASV
                     MDAMLELSRTGLGLVAVCDDQRLVKGVFTDGDLRRWLVGGGALTTPVNEAMTVDGTTL
                     QSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(12542..14056)
                     /gene="norR"
                     /locus_tag="LSX49_004170"
     CDS             complement(12542..14056)
                     /gene="norR"
                     /locus_tag="LSX49_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HBL7170503.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGAR
                     NLLQHYNFPGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVP
                     VVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD"
BASE COUNT         3327 a         3893 c         3502 g         3381 t
ORIGIN      
        1 atggcggtga ggcggggatt cgaaccccgg atgcagcttt tgaccgcata ctcccttagc
       61 aggggagcgc cttcagcctc tcggccacct caccacacgc ctcttacgag tgcttcgaag
      121 aacttgttta tcgctcatcg tcgctgcgtg gcgcacatat tactttctga gacttataag
      181 tcaaacaatt tttcccacac ttttatcgtt tgcacacttc acgctcaatt agtctgtaaa
      241 aacgtcaaaa agagtgtttt atcaacagaa aaacggaggt ctgacagata gcagtaatgc
      301 aaaaaaatgg agacttaagt tgaatgaacg ggagtaaagc gaaaagacaa tggagtgaaa
      361 gagaaatctt gagggtgcgt ctcaccgata aagatgagac gcggaaagat tagtaactgg
      421 actgctggga tttttcagcc tggatacgct ggtagatctc ttcacggtga acagaaactt
      481 ccttcggggc atttacgcca atacgtacct ggttgccctt tacccctaaa actgtcacgg
      541 tgacctcatc cccaatcatg agggtctcac caactcgacg agtcagaatc agcattcttt
      601 gctccttgaa agattaaaag agtcgggtct ctctgtatcc cggcattatc catcatataa
      661 cgccaaaaag taagcaatga caaacacatt acatctaagc agtcatggca ttacattctg
      721 ttaaacctaa gtttagccga tatacacaac ttcaacctga ctttatcgtt gtcgatagcg
      781 ttaatgcgaa tgccgtgaag cgagtccacg gcattgcctg acgcttatat tattgcaatt
      841 tcgcgctgac ccagcctttc acactggcta acgctgcagg taaggccgca gcatccgtac
      901 caccggcttg cgccatgtca ggacgtccac cacccttgcc gcccacctgc tgagcgacca
      961 taccaatcag ttcccctgct ttcacacgat ctgtgacgtc cttagatacg cctgcaatca
     1021 gagaaacctt accttcggct accgttgcca gcacgataat tgtcgacccc agctgatttt
     1081 ttaaatcgtc aaccatggta cgcaacattt tcggctcaac accgctaagc tcgctaacca
     1141 acagcttaac accattaaca tcaattgcct tactggaaag atttgcgctc tcctgtgcgg
     1201 cagcttgttc tttaagctgt tgtaactctt tttccagctg acgcgtacgt tccagtactg
     1261 aacgcacttt atcagccaga ttattgctat cgcctttcag cagatgcgcg acttcgctta
     1321 agcgatcgct gtctgcatga acggtggcga tagcgccttc tccggttacc gcttcgatac
     1381 gacgaacgcc tgcagcagta cccgattcag agatgatgcg gaacagacca atatcaccag
     1441 tgcggctggc gtgagtaccg ccacacaact cggtggagaa atcacccatg ctcagcacgc
     1501 gtacgcgctc atcatacttc tcgccaaaca gcgccatcgc acctttcgct ttcgccgctt
     1561 cgagatccat gatgttggtt tcgatcggca agttacggcg aatctgcgcg ttcaccaggt
     1621 cttcgaccgc acgaatctct tctggtttca tcgcttcgtt gtgtgagaag tcgaagcgca
     1681 gcactttgtc gttaaccagt gaacctttct gcgatacatg agtacccaga acctggcgca
     1741 gcgcagcgtg catcaggtgc gttgcggagt gattcagacg aatacgggcg cgacgagcct
     1801 catcaacatc agcctgcaca gcgtcgccca ctttcagaga acccacagca agtttaccga
     1861 tgtgaccaat cgcctggccg tatttctgcg tatcttccac cgcgaaggag aagttagcgc
     1921 ctttcagttc gcctttatca ccaacctgac cgccggattc cgcatagaat ggcgtttgat
     1981 ccagcacgac cacagcttcc tggcctgcat tgatggcatc aaccgattta ccatcaacaa
     2041 acagcgcagt cactttgccg ttcagttcca gatggtcata gcctttaaat tcagatgcac
     2101 tgtcaacacg gatcattgcg ttgtaatctg caccaaagcc gctggcttcg cgcgcacgac
     2161 gacgctgctc ttccattgct gcgtcaaaac cagcttcgtc aactttgatg ttgcgctcac
     2221 ggcaaacgtc agccgtcagg tcaaccggga agccgtaggt gtcgtacaga cggaaagcag
     2281 tttcaccatc cagcgtatca ccagaaagtt ttgccagctc ttcatccagc agcgccagac
     2341 cgcgctccag agtacgggca aactgctctt cttcagtctt cagcacctgc tcaacctgcg
     2401 cctgctggcg tttcaggtct tcacccgcag agcccataac gtcgattagc ggaccaacca
     2461 gtttgtagaa gaaggtttct ttcgcgccga gcatattacc gtgacgcact gcgcgacgaa
     2521 tgatacgacg cagtacataa ccacggtttt cattggacgg cattacgcca tccgcgatca
     2581 ggaacgcaca agaacgaatg tggtcagcga ttacgcgcag cgatttattg ctcagatcgg
     2641 tcgcgccagt gactttcgct accgcctgga tcaacgtgcg gaacaggtcg atgtcatagt
     2701 tagagttaac gtgttgcagc accgcagcaa tacgttccag acccataccg gtatctacag
     2761 acggtttcgg cagcggttcc atcgtgccat cggcctggcg gttgaactgc atgaagacga
     2821 tgttccagat ctcaatgtag cggtcgccgt cttcttccgg acttcccgga gggccgcccc
     2881 aaatgtggtc gccgtgatcg tagaagattt cggtgcacgg gccgcacgga ccagtgtcac
     2941 ccatctgcca gaagttgtca gatgcgtatg gcgcaccttt gttatcgccg atgcgaataa
     3001 tacgttcgcg cgggatccct acttcttttt cccagatttc gtaggcttcg tcgtcgcttt
     3061 catagacggt aacccacaga cgctctttcg gcagggcaaa ccatttttcg ctggtcagca
     3121 gttcccatgc aaactgaatg gcatcgtgtt tgaaatagtc gccgaagctg aagttgccca
     3181 gcatttcgaa gaaggtatgg tgacgcgcgg tgtaaccgac gttttccaga tcgttgtgtt
     3241 taccacccgc acgcacgcag cgttgggaag tggtagcgcg ggaataatta cgcttgtcga
     3301 gcccaaggaa cacatccttg aactggttca tcccggcgtt ggtaaacaac agagttgggt
     3361 cgttatgggg taccagggag ctgctggcaa ctacctgatg tcccttacta tggaaaaagt
     3421 cgagaaacgc ctgacggatc tcagcggtgc tcttgctcat aattatcctg aaatcaagct
     3481 aacgaaatat cgctaccagc cgttgcgtgt cgttaaccgc ccggctggta actgaaaagt
     3541 gggaataaga taagttttct tgactgggaa gtaaaatccc gtatgcgttc agtcggcaaa
     3601 atttcgccaa atatcctgga tatcttccat cagatagcca cgatagagca gaaaacgctg
     3661 gatcttaact ttttctgaaa agacagttgg caaaggttcg ccatattttc gcgtcgcctg
     3721 atcgcgcgcc agtgcgcacc agtcgatgtc acattcacgc atcgcttttt ctgtcgcttc
     3781 gcgggaaata cctttctgat tcagttcctg acaaatacgc gcaggtccat aacctttgcg
     3841 gctacggctg gcgataaagc gcgcaacaaa tcggctgtca tcaagatagc catgttcatg
     3901 gcaccaggca ataacgcgct cgtaatcttc tgccgtggca tcaatctctt ccgggccatt
     3961 tttgcccata atcggtgccg cgagtttacg tcgcagttct tgctcactgt gatcgcgcac
     4021 cgccagaatg cgtaccgcac gatccaacag gcgagcatat gccgggcgac gggatgttga
     4081 ttctgtcatg gcatatcctt acaacttaaa aaagcaaaag ggccgcagat gcgacccttg
     4141 tgtatcaaac aagacgatta aaaatcttcg ttagtttctg ctacgccttc gctgtcatct
     4201 acagagaaat ccggcgttga gttcgggttg ctcagcagca actcacgtac tttcttctcg
     4261 atctctttcg cggtttctgg gttatctttc agccaggcag tcgcattcgc tttaccctga
     4321 ccgatcttct cacctttgta gctgtaccac gcgcctgctt tctcgataag cttctctttc
     4381 acgcccaggt caaccagctc gccgtagaag ttgatacctt cgccgtagag gatctggaat
     4441 tcagcctgtt taaacggcgc agcgattttg ttcttcacca ctttcacgcg ggtttcgcta
     4501 cccaccacgt tttcgccctc tttcaccgcg ccgatacgac ggatgtcgag acgaacagag
     4561 gcgtagaatt tcagcgcgtt accaccggta gtggtttccg ggttaccgaa catcacacca
     4621 attttcatac ggatctggtt gatgaagatc agcagcgtgt tggactgctt caggttaccc
     4681 gccagcttac gcatcgcctg gctcatcata cgtgccgcaa ggcccatgtg agagtcgccg
     4741 atttcacctt cgatttccgc tttcggcgtc agtgccgcca cggagtcaac gacgataacg
     4801 tctactgcac cagaacgtgc cagggcgtca cagatttcca gtgcctgctc gccagtgtcc
     4861 ggctgggagc acagcaggtt gtcgatatcg acgcccagtt tacgtgcgta gattgggtcc
     4921 agcgcgtgtt cagcatcgat aaacgcacag gttttacctt cgcgctgcgc tgcggcgatc
     4981 acctgcaacg tcagcgtggt tttaccggaa gattctggtc cgtagatttc gacgatacgg
     5041 cccatcggca gaccacctgc cccaagcgcg atatccagtg aaagcgaacc ggtagagatg
     5101 gtttccacat ccatggaacg gtcttcaccc aggcgcatga tggagccttt accaaattgt
     5161 ttctcaatct ggcccagtgc tgccgccaac gctttctgtt tgttttcgtc gatagccatt
     5221 tttactcctg tcatgccggg taataccgga tagtcaatat gttctgttga agcaattata
     5281 ctgtatgctc atacagtatc aagtattttg tagaaattgt tgccacaagg tctgcaatgc
     5341 atacgcagta gcctgacgac gcaccgcatc acggtcaccg ctgaagcatt cccgccgggt
     5401 aatgccttca ccacgggcag tggcaaaagc aaaccagacg gtgccgacag gcttctcttc
     5461 actgccgcca tccggcccgg cgataccact aatagacacg gcgtaatcag cacgagccgc
     5521 tttcagtgcg cctatcgcca tttccaccac gacaggttcg ctcaccgcgc catgctgcgc
     5581 cagcgtctct tcgcgtacac cgatcatttg cgcttttgct tcgttactgt aggtgacaaa
     5641 tccgcgttca aaccaggcgg aactgccggc aatatcggta atcactttcg ctacccaacc
     5701 gccggtacaa gactcagcag ttgttacggt tgcgccacgg gctttcagcg ccagcccaac
     5761 ctgttcgctt aactgcatca gttcactttc agtcatcaca acctctgtca gtcaaaaatt
     5821 tatgccggac aagatagcac tttcccgcaa aagatgggga cgagcgattc attttacgag
     5881 tcgcgttccg aaaaaagact gttgcggcca gtcggtagag aaaaagcgct accatgccgc
     5941 gttcacattg atatgtattc acagggagag aatagcaatg gcaataaaga aaacggataa
     6001 caccccacaa aacgtgctca aacaaaccac acaaatgcgt atgtgggtca tcattggcgg
     6061 catcagcgca ctgatttccg tgatatgtaa agttttatct tctggctatc ttgaaccttt
     6121 tgacttcggt caggctgcgt taggcgttgt ctgcctggga tatgcgatat cgctgtcgaa
     6181 aaaaatcaag caattacgcc attcgaataa acagtaagat aacagaggga agtttaacct
     6241 ccctcttgca aatagttact gcacgcgcgc cagcgccacg gcctgtccta actgccagac
     6301 cgccattgcg taatgagtgc tgtggttata acgggtaata gtgtagaagt tcggcagacc
     6361 ataccagtac tggtaaccag tgccaacatc cagacgcagc aagctggcct gctgatgatt
     6421 ccccagcgac tgctgcggcg ttagtccagc tgcggcaagt tgtgaaatgc tgtacctggt
     6481 tttgaagcca ttcggtaagc ctggcgcctg accgtttgcc atcaccgcca cctgatcgcc
     6541 tttcacccag ccgtgcgctt tgaaatagtt cgctacacta ccgatggcat caaccggatc
     6601 ccacaggttg atatgcccgt caccgctgaa atccaccgca tattgtttgt aagacgatgg
     6661 cataaactga ccgtaaccca tcgcacctgc aaaggaacct ttcagattga gcggatcgtc
     6721 ctgctcgtcg cgcgccatca gcaggaaggt ttccagctca cctgaaaaat attccgcgcg
     6781 gcgagggtaa ttaaatgaca gcgttgccag cgcatcgaga atgcgagttt tccccatcac
     6841 gcgcccccag cgggtttcaa cgccgataat cccgacgata atttccggcg gtacaccata
     6901 cacctgccac gcgcgattca acgcatcttc atactgattc cagaaaacca caccgttctg
     6961 cacgttgtcc ggcgtaataa attttttgcg ataacgcagc catgcgccgt tcggacctga
     7021 tggcggtttc accgatgtgg ttggtgcctg gttatccatc agccgcagta ccgaatccag
     7081 acgtttcgcc tgggagagaa tttcctgcaa ctgctgacga tcgaaaccgt gtttgttcac
     7141 cattttgtcg atgaactgct gggcattcgg gttattggcg aagtcaccgc ccatctgcat
     7201 cacattgtgc tgcggctcaa gcaggaagcc gccagacggc gttccggtgg tcgtttcagt
     7261 ctcagtaggt tttggcttgc tgctacaggc ggcaagcaac acaaaaaggg gaagcaatgt
     7321 tacataacga cgcttgaaca tgaggggtcc atttaacaga ttcaaccagg ggcaagtatg
     7381 gtaaagcatc ccgccccgca caaggaagcg gtagtcactg cccgatacgg actttacata
     7441 actcaactca ttctcctcac taccttcttt atacaaactt tcaaaataaa atatttatct
     7501 ttcattttgc gatcaaaata acacttttaa atctttcaat ctgattagat tagattgccg
     7561 tttggtaata aaacaataaa tactgaagga gagaacaatg atagaaacca ttactcatgg
     7621 cgcagagtgg ttcatcgggc tgttccagaa aggcggagaa gtgtttaccg ggatggtaac
     7681 cggcattctt ccgctgttaa ttagcctgct ggttatcatg aacgcattga ttaattttat
     7741 cggtcagcat cgtattgaac gatttgctca acgttgcgcc ggtaaccctg tttcccgtta
     7801 tctgctgcta ccgtgcattg gtacgtttgt cttttgtaac ccgatgaccc taagcctggg
     7861 tcgctttatg ccggaaaagt acaaacccag ctattacgcg gcggcctctt atagctgcca
     7921 ctcaatgaat ggcctcttcc cccatatcaa ccctggcgaa ctgtttgttt atctcggcat
     7981 tgccagcggt ctgacgacgc tgaatctgcc acttggccca ctggcggtga gctatctgct
     8041 ggttggtctg gtcaccaact tcttccgcgg ctgggtaacc gatctgacca ccgccatttt
     8101 cgagaaaaag atgggcattc aacttgaaca aaaagttcgt ctggcaggag caacatcatg
     8161 acacgcattc ggatcgaaaa aggaacgggt ggctggggcg gcccgcttga gctggaagcc
     8221 acgccgggca aaaaaatcgt ctatatcacc gccggtaccc ggcctgcgat tgttgacaaa
     8281 ctggcacagc ttactggctg gcaggctatt gacggattta aagaaggtga acccgcggag
     8341 gcggaaattg gtgtcgcggt aatcgactgt ggcggcacat tacgctgcgg catctatccg
     8401 aaacggcgta ttcccaccat taatatccac tcgacgggca agtctggccc gctggcgcag
     8461 tacattgtgg aagatattta tgtctctggc gtaaaagaag aaaacatcac tgtagtgggt
     8521 gaggcgacac cacaaccctc ttccgtgggc cgtgactatg acaccagcaa gaaaatcacc
     8581 gaacaaagcg atggtttact ggcgaaggtg ggaatgggta tgggttctgc cgttgccgtg
     8641 ttgtttcaat ctggtcgtga caccatcgac actgtattaa aaaccattct gccgtttatg
     8701 gcgttcgtct cggcgcttat cggcatcatt atggcttccg gtcttggcga ctggattgcc
     8761 cacggtcttg ctccgctggc gagccatcca ctgggtctgg tcatgctggc gctcatctgc
     8821 tccttcccgc tgctttcacc tttcctcggc ccaggcgcag ttatcgcaca ggttatcggc
     8881 gtattgattg gcgtgcagat tggtctcggc aatattccgc cgcatctggc tttaccggca
     8941 ctgtttgcca tcaacgcgca ggcggcctgc gacttcatcc cggtcggttt gtcgctggcg
     9001 gaagctcgtc aggacacggt tcgcgtcggt gtcccttctg ttctggtgag ccgcttttta
     9061 accggcgcgc caactgtact gatcgcctgg tttgtctccg gttttatcta tcaatagagg
     9121 ctgaaacatg accgttattt atcagaccac catcacccgt attggcgcga gtgccactga
     9181 cgccctcagc gaccagatgc tcatcacctt tcgtgaaggc gcgccagcgg atctcgaaga
     9241 gtattgcttc attcattgcc acggcgagtt gaaaggtgca ctccatcccg gtttgcaatt
     9301 tacgctcggg cggcatcgct atccggtgac cgccgttggc agcgtggcgg aagacaacct
     9361 tcgcgaactg ggtcatgtca ccctgcgctt cgatggttta agcgaagcgg aatttccggg
     9421 cactgtccat gtggcaggcc ctgtacccga cgatatcgcg ccgggatcgg ttttgaagtt
     9481 tgaatctgtt aaggagtaaa aaatgaatca ggttgccgtt gtcatcggtg gtgggcaaac
     9541 cttaggcgcg ttcctgtgcc acggtctggc tgccgagggg tatcgcgtgg cggttgtcga
     9601 tattcagagc gacaaagccg caaatgtggc acaagaaatt aacgccgaat atggtgaagg
     9661 aacagcgtac ggttttggtg ctgacgccac cagcgagcaa agcgttctgg cgctttctcg
     9721 tggggtagat gaaatctttg gtcgcgtgga tttgctggtc tacagcgccg gaatagcaaa
     9781 agcagccttt atcagcgatt tccagcttgg agattttgac cgttcgctac aggtgaatct
     9841 ggtgggttat ttcctgtgtg cccgtgaatt ttcgcgtttg atgattcgcg acgggattca
     9901 gggtcgcatt attcagatca actcgaaatc cggcaaagtg ggcagcaaac acaactctgg
     9961 ctacagcgca gcgaaatttg gtggcgtcgg gctgactcaa tcactggcgc tggatctggc
    10021 ggagtacggc attacggtgc attcgctgat gctcggtaac ctgctgaaat cgcctatgtt
    10081 ccagtcactg ttgccacaat acgcgaccaa gctgggtatc aaaccggagc aagtcgagca
    10141 gtattacatc gataaagtac cgctcaaacg cggctgcgat tatcaggatg tgctgaatat
    10201 gctgctgttc tacgccagtc ctaaggcgtc gtactgcact ggtcagtcga tcaatgtcac
    10261 cggcggtcag gtgatgttct gatcaacagc ggagatcttt taaggatctc cgcgcgacta
    10321 atagaatgcc tgatgcgcta cgcttatcag gcctacagga cttccgccac tacatcacgg
    10381 agaagttatg gtatccgcac tcatcaccgt cgccgttatc gcctggtgtg cgcaactggc
    10441 cttaggcggt tggcaaattt ctcgttttaa ccgtgccttc gacacactat gccaacaagg
    10501 gcgcgttggc gtgggacgtt ccagcgggcg ctttaaacca cgggtcgtgg tcgccatcgc
    10561 gctggacgat cagcagcgca tcgtcgacac cttgtttatg aaaggactga ccgtcttcgc
    10621 ccgaccgcaa aaaattcccg caattaccgg catgcatgcg ggtgatttac agcccgatgt
    10681 gatctttccc catgatccac tatcacagaa tgctctatca ttggcgctta aactgaaacg
    10741 tggataattt cgttgtgaat gttactagct tgcgaagtta tcattttgaa acctaaatca
    10801 ggtaatcacg cccatgaaac ctcgtcagcg tcaggccgcc attctggagt atctgcaaaa
    10861 gcagggtaaa tgctcggttg aagaattggc gcaatacttt gacaccacag gcacaaccat
    10921 tcgcaaagat ctggtcattc tggaacatgc cggaaccgtc attcgtactt atggcggcgt
    10981 ggtgttgaac aaagaggaat ccgatccgcc tatcgatcat aaaacgctta tcaacaccca
    11041 caagaaagag ctgattgcag aagctgccgt tggttttatt catgatggcg actcaataat
    11101 tcttgatgct ggcagtaccg tgttgcagat ggtgcctctg ctctcacgtt ttaataacat
    11161 cacggtgatg accaacagtc tgcacatcgt caatgcgcta tccgaactgg ataacgaaca
    11221 aactatcctg atgccaggcg gaacatttcg taaaaaatcg gcctcatttc acgggcaact
    11281 ggcagagaat gccttcgagc atttcacctt cgataaattg tttatgggca ccgacggcat
    11341 cgatctcaat gcgggcgtaa ccacgttcaa cgaggtttat accgtcagta aggcgatgtg
    11401 caatgccgcg cgcgaagtga ttttgatggc tgactcatcg aagtttggtc gtaaaagccc
    11461 caacgtggtt tgtagtcttg aaagcgtcga taagctgatt accgacgcag gtatcgatcc
    11521 agcgtttcgt caggcgctgg aagaaaaagg gatcgacgtg atcataaccg gagagagcaa
    11581 tgagtgaagc actactgaac gcgggacgtc agacgttaat gctggagttg caggaagcaa
    11641 gtcatttacc ggaacgtctg ggcgatgatt tcgttcgcgc cgccaatatc atcctgcact
    11701 gcgaaggcaa agtggtggtt tcgggaattg gcaaatcggg ccacattggt aagaaaatcg
    11761 ccgcaacgct tgccagcacc ggcacaccgg ctttttttgt ccatccggca gaagcactgc
    11821 acggcgatct ggggatgatt gaaagccgcg atgtgatgct gtttatctct tattccggtg
    11881 gcgcgaagga actggatctc attattccgc gtctggaaga caaatctatc gcgctgctgg
    11941 caatgaccgg aaaaccgacg tcaccgctgg gcctggcggc gaaagcggtg ctggatatct
    12001 ccgtagaacg cgaagcctgc ccgatgcacc ttgcgccgac ctccagcacc gtgaataccc
    12061 tgatgatggg cgacgcgctg gcgatggcag tcatgcaggc gcgtggtttt aatgaagaag
    12121 attttgcacg ctcccaccca gccggggcac tgggcgctcg cttgctgaac aaagtgcatc
    12181 atcttatgcg tcgtgacgat gccatcccgc aggtagcgtt aaccgccagc gtgatggacg
    12241 cgatgctgga acttagccgc accggtttag gtctggtggc agtgtgcgat gatcaacgac
    12301 tggtgaaagg cgtctttacc gacggtgatt tacgtcgctg gctggttggc ggcggcgcac
    12361 tcaccacgcc agtcaatgaa gcgatgacgg tcgacggcac cacgttgcaa tcgcaaagcc
    12421 gtgccatcga cgccaaagaa atcctgatga aacgaaaaat caccgccgca ccggtagtgg
    12481 atgaaaacgg caaactcacc ggcgcaatta acctgcagga tttctatcag gccgggatta
    12541 tttaatcctt cagccccaga cgtttcgcca gccgatgcag gttggcgacg tcggtttcca
    12601 gcatccgcgc acaggcggcc cagttgtgat gattttgcgc cagtgcctga cgaatggttt
    12661 cacgctggaa cgcttctgtc gcttcacgca gattttgctt aacaacgggc accgccgccg
    12721 cttctggcgg cggcaacgtc acctcaggaa aagcaaaatg ttgcgcctca agaatcactt
    12781 catcgccgct gcgggtggct ctcgacaata ctaccgcccg atgaatagca tgttccagtt
    12841 cgcgcacgtt tcccggaaaa ttgtagtgtt gcagtaaatt tcgcgctccg gcacttaata
    12901 ccacgcggga gagccccagc cgcaaacgac actgctcgca gaaatacccc gccagcagaa
    12961 tgacatcatc gccccgctca cgcagcggcg gcactgaaag tggaaacacg ctcaggcggt
    13021 ggaacaagtc agcgcgaaat cgccctgcca gtacctcttc gcgtaagtca cggttagtcg
    13081 ccgccagcac gcgcacatcg acccgcaaac tgcggtcatc gccaacgcgt tgaatatcgc
    13141 catactgcaa caccctcagc agcttggcct gcaatgccaa cgacaactcg ccgatctcat
    13201 cgagaaacag cgtgccgtta tccgccattt caaacttccc gctgcggtta ctgatagcac
    13261 cagtaaacgc ccctttcaca tgcccgaaca actcactttc cgccacactt tccggcagtg
    13321 cggcacagtt gagatagacc agcggattca ccgcccgtgg cgaggcttca tgaatcgctt
    13381 tcgccaccag ctccttaccg gttcccgtct caccgctaat taaaacgttg agatcggatg
    13441 ccgccacaat ctcaatctct tttttcaatt gcgtcatgcc tggggacaaa ccaatcatct
    13501 gcgtctgttt caccgcttca aacggcgcgg catcgcctgg cagcatattc tggctttcca
    13561 gttgttcaat cagtaacgca ttgcttaacg ctcccgccgc cagcgcagca atcaggcgta
    13621 actcttcgtc gctgaaaaca tcgaactgat cgggctgcat cccgtcgagc gtcaaggcac
    13681 cgatcaggtt ttgcccggca aacaacggca aaccaacgca ggcgtgaacc ttcagactct
    13741 cctgccctgg aatcagaccg tcataaggat cgggcaattc gctgtctgcg ggaaagcgca
    13801 ccacatcacc cgcgcgggca atcgcttcca gccgtggatg cccttccagc gcaaagcgtc
    13861 taccgagtac atccttcgcc agcccgtcga tggcaagcgg aataaactgc cgcgagtcgt
    13921 aacgtagcaa cgcagacgca tcgcactcca gcacctgacg cagcgtagtg atcaggcgct
    13981 gaaaacgatc ctgatgacca atcccacgct gcaattcgat ggcgatattc gccagcacat
    14041 caacggaaaa actcatcttt gcctcactgt caatttgact atagatattg tcatatcgac
    14101 cat
//
LOCUS       DAFGPF010000123        14020 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFGPF010000123 DAFGPF010000000
VERSION     DAFGPF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14020
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.123"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            13..1155
                     /locus_tag="LSX49_004171"
     CDS             13..1155
                     /locus_tag="LSX49_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBL7170504.1"
                     /translation="MTNKHPSLFSPFMLTEKIKLRNRIVMAPMTTWSANPDGTISEQE
                     LEFYKRRSQNVGLVITGCTYVTPSGIGFTHEFAAYDDRFINSLEKLAAAAKSGGAPAI
                     LQIFHAGNKAIPELVPNYDVISASASSVKSGDFMKRVVQSREMTENEIQETIRAFGDV
                     TKRAIKAGFDGVELHGAHGFLLQNFFSPLFNQRNDRWGGDLEGRMRFPLAVLQEVKNV
                     VYEYATKPFAIGYRISPEESVTGGLRIEDTYKLLDRLISSGISYIHTSLVSINDSYPV
                     ESPNGPRTIELILNHIAGRVPVIAAGKIRTPSQAQEAISAGLPLVAIGKGLVINPEWV
                     TLAESGRSHEIQTALNPQRVPELTIPDKLWDQIQASKGTGWFPLMD"
     gene            1628..1729
                     /locus_tag="LSX49_004172"
     CDS             1628..1729
                     /locus_tag="LSX49_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170505.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
     gene            2094..2357
                     /locus_tag="LSX49_004173"
     CDS             2094..2357
                     /locus_tag="LSX49_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBL7170506.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     gene            2357..2497
                     /gene="ykgO"
                     /locus_tag="LSX49_004174"
     CDS             2357..2497
                     /gene="ykgO"
                     /locus_tag="LSX49_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HBL7170507.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(2567..2757)
                     /locus_tag="LSX49_004175"
                     /pseudo
     CDS             complement(2567..2757)
                     /locus_tag="LSX49_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3581..4123
                     /gene="ecpR"
                     /locus_tag="LSX49_004176"
                     /gene_synonym="matA"
     CDS             3581..4123
                     /gene="ecpR"
                     /locus_tag="LSX49_004176"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HBL7170508.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKLYKLVQ"
     gene            4198..4785
                     /gene="ecpA"
                     /locus_tag="LSX49_004177"
                     /gene_synonym="matB"
     CDS             4198..4785
                     /gene="ecpA"
                     /locus_tag="LSX49_004177"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HBL7170509.1"
                     /translation="MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            4842..5510
                     /gene="ecpB"
                     /locus_tag="LSX49_004178"
                     /gene_synonym="yagY"
     CDS             4842..5510
                     /gene="ecpB"
                     /locus_tag="LSX49_004178"
                     /gene_synonym="yagY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HBL7170510.1"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIQNS
                     TDSGRLINIRLERLSSPLDDGQVIAMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            5536..8061
                     /gene="ecpC"
                     /locus_tag="LSX49_004179"
                     /gene_synonym="yagX"
     CDS             5536..8061
                     /gene="ecpC"
                     /locus_tag="LSX49_004179"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HBL7170511.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMTLANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNFGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQIWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTFSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSNIASI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSSANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASGRTDGNAGVIFDTGLENDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     gene            8051..9694
                     /gene="ecpD"
                     /locus_tag="LSX49_004180"
     CDS             8051..9694
                     /gene="ecpD"
                     /locus_tag="LSX49_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HBL7170512.1"
                     /translation="MRVNLLIAMIIFALIWPATALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYLQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            9663..10373
                     /gene="ecpE"
                     /locus_tag="LSX49_004181"
     CDS             9663..10373
                     /gene="ecpE"
                     /locus_tag="LSX49_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HBL7170513.1"
                     /translation="MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNLTKRSPSGGEVSTEPVVVMDTILVVRPRQVQFKWS
                     FDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            10680..11009
                     /locus_tag="LSX49_004182"
     CDS             10680..11009
                     /locus_tag="LSX49_004182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBL7170514.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYENRSSTCREFAMSGENGEVNEACNRARA
                     KYGLTPL"
     gene            complement(11021..11184)
                     /locus_tag="LSX49_004183"
                     /pseudo
     CDS             complement(11021..11184)
                     /locus_tag="LSX49_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(11258..11872)
                     /locus_tag="LSX49_004184"
     CDS             complement(11258..11872)
                     /locus_tag="LSX49_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HBL7170515.1"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNSAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     gene            complement(12087..12272)
                     /locus_tag="LSX49_004185"
     CDS             complement(12087..12272)
                     /locus_tag="LSX49_004185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170516.1"
                     /translation="MASGLICHGGFEPHAWGVASLMDVTVLVVASLLVWLLVNRENHY
                     ARGIPQDVQVLHKKAHH"
     gene            12321..12479
                     /locus_tag="LSX49_004186"
                     /pseudo
     CDS             12321..12479
                     /locus_tag="LSX49_004186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706266.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            12705..>14020
                     /locus_tag="LSX49_004187"
     CDS             12705..>14020
                     /locus_tag="LSX49_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HBL7170517.1"
                     /translation="MTFTITQDRQLASLTVTKEEKEILFAVKSKAGGGLFIRVRYGSD
                     NKSWIYRYRIAQKPAKLTLGSYPAMGLAQARKAHADAIELVRKGIDPRHIRKNEKQKN
                     EQMIIYSELWKDWIEFRKTSKPISTRTLADYEGTYHRHLEKALGNLRIDELTKSVIFE
                     HLSNVRKTSSEAVRKGLIILNMTLDHANLQGMLEHNPARLLKPAMFGASMNKPRERWL
                     PENELRMLWKALDDATVGGGSIASGGYGISSSVVLSHSVANALRLIIFTGVRRSEAAQ
                     MRWDQINGERWTIPATKNGKSHIVTLHPYMLSLIKTQREFTEGAYVFGSTSKPGFPIT
                     NDALTRALERVRSKYLAELTPFSPHDLRRSVATGCAEYLDAPERLIELLLNHVPKDRL
                     IRTYQVGQQAEKLKNLFIEWGNFIMNNVITVQQNAPDNVIHIKFGN"
BASE COUNT         3962 a         3320 c         3238 g         3500 t
ORIGIN      
        1 tgaggtattg ttatgacaaa taaacaccca tcattgtttt ctccttttat gctgacagaa
       61 aaaataaagc tacgtaatcg tatcgttatg gctcctatga caacctggtc agctaatcct
      121 gatggaacca tctctgagca agaactcgaa ttttataaac gtcgctcaca aaatgttggt
      181 ttagtaataa caggatgtac ctatgtcacg ccaagcggca ttgggtttac tcatgaattt
      241 gccgcgtatg acgaccgttt cattaacagc cttgaaaagt tagcagctgc agccaaaagt
      301 ggcggtgctc cggctatttt gcagattttc cacgccggta ataaagccat cccggagctt
      361 gtgccaaatt acgatgttat tagtgccagc gcatcaagcg taaaatctgg tgactttatg
      421 aagagagtgg tacaaagcag ggaaatgact gaaaacgaaa ttcaggaaac cattagagca
      481 ttcggagatg tcacaaaaag ggcgattaaa gcaggttttg atggcgttga acttcatggt
      541 gcgcacggat tccttctgca gaatttcttc tcccctctat ttaaccagcg taatgaccga
      601 tggggaggag atcttgaagg acgtatgcgc ttcccgctgg ccgtattaca ggaagtaaaa
      661 aatgtagtct atgaatatgc gacaaagccc tttgctatcg gttacagaat atctcctgaa
      721 gaatctgtaa cagggggact gcggatagag gatacttata aactccttga tcggctcatt
      781 tcatccggta tttcgtatat acatacctcg ctggtcagta ttaacgatag ctaccctgtt
      841 gagtcgccaa atggtccccg aactattgaa ttgattttaa atcatattgc aggcagagtg
      901 ccggtaatcg ccgcaggtaa aatacgcaca ccgtctcagg ctcaagaagc aatttccgct
      961 ggcctgccac ttgttgcgat cggtaaaggg ctggtgataa atccagaatg ggtgacttta
     1021 gctgaatcag gtagaagtca tgaaattcaa acagccctta atccacaacg cgttcctgaa
     1081 ttaaccattc cggataaact atgggatcaa attcaggcat cgaaaggaac tggctggttt
     1141 ccgttaatgg attaaatatc gattactctc ccgagagtaa aactatcaaa tcaatgagta
     1201 accgatacag cctcgcaaat tctttcagat aattaacccg tcactgcggc acgttctctc
     1261 gcaaggcgtg cctgcagtgt aatccagtat gtatccggca tagttgacgg tttaatagac
     1321 tcaattcctc tccctggtta cctacaacga tatcttgtat aacaccccag gagatacgac
     1381 gttacgatga gatgcgatat gctcctcagc gccaatcaac gccaggactg ggccagtctt
     1441 gagatcagac tcattcccgt aactgatttc aggcgacata tatcaatgac gttggggcaa
     1501 taaaagatag ccgatgtaat acatctattc aaatttgtga tacatgtcaa aaaattggtt
     1561 gaccaaactc gttatttata taagggcact tacgaagtgc actctttttt aaagcgagga
     1621 agtaccaatg aaagagaata aagtacagca aatcagtcat aaactgatta atatcgttgt
     1681 ttttgtcgca attgtagaat acgcctattt atttctccat ttctattaat aacggcaata
     1741 aactgttcac ttcagtgata tttaaaatat gcatcctctc ccttttttgt aagtaattat
     1801 tatatccgtg ggagaggaat acacattgtc aggtaatcaa tcatgctgca ataaatcatc
     1861 ggccagtaaa gtggagatag cctccattct cgaaaaatcc atactctcag cgaaaccatc
     1921 atcaatcact catccaggcg tttatgggag cgtcgccaat ggctgctaac aatgccagac
     1981 ttccccgttg cggaaattcc acatcccaca aatagtcaca gtgattgggt gttgaaatga
     2041 tccggatgag catgtatctt tacggttatg ttataacata acaggtaaaa atgatgaaac
     2101 ccaatatcca tcctgagtat cgtactgtgg tgttccacga caccagcgtt gatgagtact
     2161 ttaaaatcgg ctcgactatc aaaacagacc gtgagattga gctggatggc gtaacgtatc
     2221 cgtacgtaac aattgatgtc tcttcgaaat cgcacccgtt ctatacaggg aagctgagaa
     2281 cagtggcatc agaaggaaat gttgcacggt tcacccaacg ttttggtcgt tttgttagca
     2341 cgaaaaaggg ggcatgatga aagtccttaa ctctctgcgt accgcaaaag aacgccatcc
     2401 agactgtcag attgtgaagc gaaaaggacg gctgtatgtg atttgtaaat ctaatccacg
     2461 ttttaaggcc gttcagggtc gtaagaaaaa acgttgattt aaaattcgac gaattaacga
     2521 tatttgtctg attaataatc agaccggatt aatgttggtg tatttattac accagcatta
     2581 attttcctgg ggatgtatct tcctgttcat ttaaggtcaa ctgcctgacg tttctctccg
     2641 aatattccat tatattaatg ttgacttgtt gaccagcttc gccctgtatg ctggcatcaa
     2701 ctctctttta gactgaacac gccactcagt ttcctccctt tgcgacgcag cctgcattta
     2761 cactcaaact gttaagatga taaatgtggt aaatctgttg gtactgacat aaaaacgttt
     2821 acgccacagg aacggccaga tccatcggta accccatcgc cgacgttcga gtgccagtta
     2881 gagtaacgcg cacagatgac tgaatgcagt gccctggcaa agaggccatc gttcctgtga
     2941 caactggcag tcttcgttta acttcactta atttagctct tagggggctt accggacaga
     3001 tgacgtactt acacctgttt aattttccat cacttattgg aatgaacacc cataaccatt
     3061 ttgtgcggca tgttaatcca ttaaaacacc ttactgattg gcaaatcatc tttaattatg
     3121 acttatgata gttttatatt ctatttctta tcatttaaac ttgttttttt actagtccat
     3181 tacacaacac attaagacta ttcctaacac ctcagggcaa agttcctggc taatataaaa
     3241 tgcaagtaag aattgaacgt tatattgcca ataaccttat gaaactgaat gtctttttct
     3301 tcttatcaaa aaagcaatat tttcattttt tgtaaatatt gacttaacca tggaattcat
     3361 tttctgttca catattgaca ctcatcagga aaaaaacata aatttaaacc taatcgaaat
     3421 aattaaaact taatctcgtt taacctatat tgatatgtgc tacgtatctt atttacttcc
     3481 gatttactaa aaaaactgaa tgtacctgta aaaattacag gtttggaaag tagtgacatg
     3541 gcaaaatgat tacagcaggg actatgaggt taaaaaccat atggaatgtc aaaaccgttc
     3601 tgataaatac atctggtctc cccatgacgc ctacttctat aaaggactat ctgaactgat
     3661 tgtggatatc gacagattaa tttatctatc gctggagaaa atcagaaaag atttcgtgtt
     3721 tatcaatctc aatacggatt ctttaactga gtttataaac cgtgataatg agtggttatc
     3781 cgcggtaaag gggaaacagg tcgtattgat tgcggccaga aagtcagaag ccttagcaaa
     3841 ttattggtat tacaacagca atattagggg cgtggtatac gctggactga gtcgtgatat
     3901 tagaaaagaa ctggcctatg tgattaatgg caggttcctg agaaaagata ttaagaaaga
     3961 taaaatcact gaccgggaaa tggaaattat ccgcatgacg gctcagggaa tgctgcctaa
     4021 atcgattgcc agaattgaaa attgtagtgt gaagacagtg tatacccatc ggcgtaatgc
     4081 agaggccaag ctgtactcaa aattatataa gttggttcag taaactccag gcaagttagt
     4141 tttaaaaaat gactcaccgg gacttcatgt cctcaattca actcgggaag aaaagcaatg
     4201 aaaaaaaagg ttctggcaat agctctggta acggtgttta ccggtacagg tgtggcgcag
     4261 gctgctgacg taacagctca ggctgtagcg acctggtcag caacagccaa aaaagacacc
     4321 accagtaagc tggttgtgac gccactcggt agcctggcgt tccagtatgc cgaaggcatt
     4381 aaaggtttta actcacaaaa aggtctattt gacgtggcta tcgagggtga ctcaacggct
     4441 accgccttta aactgacctc acgtcttatc accaacacct taacccagtt ggatacctca
     4501 ggttccacac tgaatgtggg cgtggattat aacggcgcgg cagtcgaaaa aactggcgat
     4561 accgtgatga tcgataccgc caacggcgta ctgggcggca accttagccc actggctaac
     4621 ggttacaatg ccagcaatcg taccactgca caggatggtt tcactttctc catcatcagc
     4681 ggcaccacca atggtaccac cgcagtaacc gattacagca ctctaccgga aggcatctgg
     4741 agcggcgacg ttagcgtaca gttcgacgct acctggacca gttaatctct ctgatgtacc
     4801 agcaggggta cccccctgct ttattcctgg acggaattgt tatgaaaaag caccttctgc
     4861 ctctcgctct gctgttttcc ggaatatcac cggcccaggc gctggatgtc ggcgatatat
     4921 catcgtttat gaacagtgac agcagcacgc tgagcaaaac gatccaaaac agtaccgaca
     4981 gtggccgcct catcaatatc cgtctcgaac ggctctcttc accgcttgac gacgggcagg
     5041 ttatcgcaat ggacaagccg gatgagttgc tactcactcc cgccagcttg ctgctacccg
     5101 cccaagccag cgaagtgatc cgcttcttct ataagggacc agcagatgaa aaagagcgct
     5161 actaccgcat tgtctggttt gatcaggccc tcagtgatgc gcagcgcgat aatgccaacc
     5221 gcagcgctgt ggccactgcc tccgcccgca tcggcaccat cctggtcgtc gcaccccgcc
     5281 aggcaaacta ccactttcag tacgccaacg gctccctgac aaatacagga aatgcgacgc
     5341 tgcggatcct cgcctacggc ccctgcctga aagccgccaa tggtaaggag tgtaaagaga
     5401 attactacct gatgccgggc aagtcgcgtc gttttacccg cgtggacacg gcggataaca
     5461 aaggacgggt tgcactttgg cagggtgata agttcattcc cgtgaaatag atagctgtgc
     5521 agatggataa cgacaatgcc tttacgacgg ttctccccag gactgaaagc ccagtttgcc
     5581 ttcggcatgg tctttttgtt cgttcagccc gatgccagcg ctgctgacat aagtgcgcag
     5641 caaataggtg gggtgattat tccgcaggcc ttcagtcagg cgctccagga cggcatgagc
     5701 gtcccgcttt atattcatct cgccggtagc cagggtcgcc aggacgatca gcgaatcggc
     5761 agcgctttta tctggttgga tgatggacag ttacgcatcc gaaaaataca gctggaagag
     5821 agtgaagata acgccagtgt cagcgaacaa actcgacagc agctgatgac tctggccaac
     5881 gccccgttca atgaggccct taccatcccc ctgactgaca acgcgcagtt ggatctcagc
     5941 ttgcgccaac tgctgctgca gctggtggtc aagcgcgaag cgctgggcac cgtactacgc
     6001 tcacgtagcg aagacatcgg gcagtccagt gttaacaccc tcagcagtaa tctgagctat
     6061 aacttcggcg tctataacaa ccagttgcgt aacggcggga gcaacacctc cagctatctg
     6121 tcgctgaata acgttactgc gctgcgcgaa catcacgtgg tgctcgacgg ctcactgtac
     6181 gggattggta gcggtcaaca ggacagtgaa ttatataaag cgatgtatga acgcgatttt
     6241 gctggtcacc gatttgccgg tggaatgctc gacacctgga acttgcagtc cttagggccg
     6301 atgaccgcca tttcagcagg gaagatttac ggcctttcct ggggaaacca ggccagctcc
     6361 accatcttcg acagcagcca gtcggccacg ccagtgatcg cctttttacc ggcggcgggc
     6421 gaagtacatc tcacccgtga tgggcggcta ctaagcgttc agaacttcac catgggcaat
     6481 catgaagtgg atacccgggg tctaccgtac ggtatttacg atgtggaagt tgaggtaatc
     6541 gttaacggtc gcgtgatcag caaacgcacc cagcgggtca ataagctgtt tagccggggg
     6601 cgtggcgtcg gtgcaccgct ggcgtggcag atatggggcg gtagctttca tatggatcgc
     6661 tggtcggaaa acgggaaaaa gacgcgacca gccaaagaga gttggctggc aggtgcctcg
     6721 acctccggct cactgagtac gtttagctgg gcggcaacgg gatatggata cgataatcag
     6781 gcggtgggtg aaacccgtct gacgcttccg cttggggggg cgatcaacgt taacttgcaa
     6841 aacatgctgg ccagtgacag ctcatggagc aacatcgcca gcatcagcgc cactctacct
     6901 ggaggcttca gttcgctgtg ggttaaccag gaaaaaaccc gcattggcaa tcaattgcga
     6961 cgtagcgatg ccgacaaccg tgcaatcggc ggcacactca acctgaactc actgtggtcg
     7021 aagctgggta cgttcagcat cagctacaat gatgaccgcc gctacaacag ccactattac
     7081 acggcagatt actatcaaag tgtctacagc ggtacctttg gttcgcttgg cctgcgggcc
     7141 ggtattcagc gctataacaa cggcgacagc agcgccaata cagggaaata tatcgctctc
     7201 gatctctcgc taccactggg caactggttt agcgcaggga tgacccatca aaacggctac
     7261 accatggcaa acctgtcagc acgcaaacag tttgatgaag gaaccattcg cactgttggt
     7321 gccaatctgt cacgagccat ctccggcgat accggtgatg acaaaaccct cagcggtggg
     7381 gcgtatgcac agttcgacgc tcgttacgcc agcggaacgc tgaacgtcaa tagcgcggcg
     7441 gacggctaca tcaatactaa tttgaccgcc aacggcagcg tcggctggca gggtaaaaac
     7501 atcgctgcca gcgggcggac cgatggcaac gctggggtga tattcgacac tggcctggag
     7561 aacgatggtc agatcagcgc caaaatcaac gggcggattt tcccgcttaa cggcaagcgt
     7621 aactatctcc cgctctctcc ctatggaaga tatgaggtgg agttgcagaa cagcaaaaac
     7681 tcactcgaca gttacgatat cgtcagcggt cgcaaaagtc atctgactct ctatccaggc
     7741 aatgtcgctg tcattgagcc agaggtgaag cagatggtta ccgtctccgg tcgtatccgt
     7801 gcggaagacg gcacactgct ggctaacgca cggattaaca accatatcgg ccgaacccga
     7861 accgatgaaa acggcgagtt tgtcatggac gtggataaga aataccccac tatcgatttt
     7921 cgctacagtg gcaataaaac ctgcgaagtg gcactggaac tcaaccaggc gcgcggtgcc
     7981 gtctgggtcg gtgatgtggt ctgcagcggc ctctcatcgt gggcggcggt gacgcagaca
     8041 ggagaagaga atgagagtta acctactgat agcgatgata atctttgcgc taatctggcc
     8101 tgcaaccgcg ctcagagcgg cagtgagcaa aacaacctgg gcggatgctc cggcacgcga
     8161 gtttgtgttt gtcgaaaaca actcagacga caactttttc gtcactcctg gcggggcgct
     8221 ggatccgcgc ctgaccggtg ccaaccgctg gaccggttta aaatacaatg gttcaggaac
     8281 catctatcag caaagcctcg gctacattga taacggttac aacaccggcc tttataccaa
     8341 ctggaagttt gatatgtggc tggaaaattc accagtttca tctcctttaa ctggcttgcg
     8401 ctgcatcaac tggtacgcag ggtgtaatat gaccaccagt cttatcctgc cgcaaaccac
     8461 cgacgccagt ggattttatg gcgcgacggt gaccagcggc ggcgcgaagt ggatgcacgg
     8521 catgttgtca gacgcgtttt accagtatct gcaacaaatg cccgtcggca gcagctttac
     8581 aatgaccatc aatgcctgcc agacctctgt gaactatgac gccagcagcg gcgcacgctg
     8641 taaggatcag gcctccggca actggtatgt tcgcaacgtc acccatacga aagcagcaaa
     8701 tctgcggttg ataaataccc actcgctggc ggaagtattt atcaacagcg acggagtacc
     8761 gactctgggc gaagggaacg ccgactgccg gacgcaaacc atcggcagcc gttcaggatt
     8821 aagttgtaag atggttaact ataccctgca aacaaacgga ctcagcaaca cctcaatcca
     8881 tatattcccg gcgatcgcca actcgtcgtt agcctcggcc gtcggggcgt acgatatgca
     8941 gttcagtctg aatggcagtt catggaaacc ggtgagcaat actgcctatt actacacctt
     9001 caacgagatg aagagcgcag actcgatcta tgtgttcttc tcgagcaact tctttaagca
     9061 gatggtgaac ctcgggatca gcgatatcaa caccaaagat ctgttcaact ttcgctttca
     9121 gaacaccaca tcaccggagt ctggctggta tgaattttct acctccaaca cgctgattat
     9181 caaaccccgt gatttcagca tcagtattat ctccgatgaa tatactcaga caccgtcgcg
     9241 ggagggatat gtcggcagcg gcgagtcggc actcgatttc ggctatatcg taaccaccag
     9301 cggtaaaaca gctgccgacg aagtgctgat caaggtgacc ggacccgcgc aggtgattgg
     9361 cgggcgctcc tattgtgtct tcagctccga tgacggtaag gcgaaagtac cgttcccggc
     9421 gacgctttcc tttattaccc gcaacggagc tacaaaaacc tacgatgccg ggtgcgatga
     9481 tagctggcgg gatatgaccg atgcgctgtg gttgaccaca ccgtggactg atatctctgg
     9541 cgaagtgggg cagatggata agaccacagt caaattttcg attccaatgg ataacgccat
     9601 ttctctgcgt acggtagatg ataacggctg gtttggcgaa gtcagcgctt caggagagat
     9661 tcatgttcag gcgacgtggc gtaacattaa ctaaggccct gctgacagtg gtctgtatgc
     9721 tggcggcacc tttgacacag gcgatttcgg tcggcaatct gactttttca ctgccgtccg
     9781 agactgactt tgtcagcaaa cgtgtcgtga ataacaacaa aagcgcacgg atataccgta
     9841 ttgccatcag tgctattgat agcccgggca gcagtgaatt gcgcacccga ccggtggatg
     9901 gtgaactact tttcgccccc cgccagctgg cgttgcaggc tggtgagagc gagtatttta
     9961 aattttacta tcatggccca cgggataacc gcgagcgcta ctaccgggtc tcatttcgcg
    10021 aggtccccac tcgtaacctg acaaaacgca gcccaagcgg cggtgaggtc agcacggagc
    10081 cggtggtggt gatggatacc attctggtag tacgaccacg tcaggttcag tttaaatggt
    10141 ccttcgatca ggtgacagga acggtaagta acaccggcaa cacgtggttt aagctactga
    10201 ttaaaccagg atgtgattcg accgaagagg aaggcgatgc ctggtatcta cgtccgggag
    10261 acgtggttca tcagcctgag ttacgtcagc cggggaatca ttatctggtc tataacgaca
    10321 aattcattaa gattagcgat tcctgtccgg ctaagccccc ttcggcggac taagacttat
    10381 ccatcggacg agggaagaat tccacctcag agactcaaaa atcgtttaaa tgatgtggaa
    10441 gcgatcgtca atgtcaccga tgagctttct catatgcaca ccacagtgtt caggagacac
    10501 ggaaaggtac caggcggcct gctaacgagt ggtttcttca ctaattagga cgtaaaatcg
    10561 gtaacggctg gaaatcattc aatactcaca ctatcgaaag tacaccagcc aaccgcgata
    10621 cgtccctgca tacgacgtac cgcagttatc tttacgattt atagctgtac tggtgaatta
    10681 tgagcaattt gaatccatgc atgacgtgtg gtgcctgttg tgcatttttc cgcgtctctt
    10741 tttactgggc cgaagccgac gatgctggcg gtaccattcc cgccaggctc actgaacaaa
    10801 tatccccttt tcaccgatgc atgagcggta ctaatcagaa aaatccccga tgtattgccc
    10861 ttgcaggaac accgggcaaa aatgcctgct gcacgatata tgaaaatcga tcgtccacat
    10921 gcagagaatt cgccatgtct ggtgagaacg gagaagtcaa tgaggcttgc aatcgtgcaa
    10981 gagctaaata cgggctaaca ccgttataaa tatacaataa ttaattgcat tgccccgcca
    11041 gctgtaatag cggggcttcg tttttcaggg acaacaaaac ctgaaacttc ttccattttc
    11101 cagcaacaat gcctcttctt ctgtagcgtc ctccggatct acatcatcct gaagtagcgc
    11161 gatatgatca ctgactgtcc gcatcagaat atgaaaagca acgtttttaa cctataaaaa
    11221 tggcgctata tttgcgccat ttttatcatt caaagcatta tctatttgag cctaaaggga
    11281 tctcaggatc tggctcatgg gtaattctgt ttcgtaaatc tctgcgaata atttcaatag
    11341 accagaacca gactaaatgt ccaaaaattt cagagacatt ctcataccac ggaagatcaa
    11401 agagaggtgg cgtaagtccc atgagaggga atgaaatcat atgaacaaaa agttgcgcta
    11461 aagcacctgc cagtaagccc tgccaaagtt taattttcgg aaatacttcg gcgaccacac
    11521 agtaaccaac ggcaaaaact atcgaaaaga ttatgtgcgt tacaccaacc cagttaaaga
    11581 catgcccggc gaaggtataa acagccgaat ttggatctgt cagtcccaac caatcccgaa
    11641 gaaaaatgta cggaggattg agaaagttac gggagcaatc aatttggcct gcagccctga
    11701 ttaatgattc cggaccacac gctgcattaa acatatcaac cggactacgt ggtggcaatg
    11761 gaacttctgc cccccactta acaaatgcgg aaacaacgcc agcaatcagc ccaatgaatg
    11821 cagcaagacc ataacgtctg cggtttggtg gagtttgttc aaatatattc atatctaccc
    11881 tgcttgtacc attatgttat acacctcttt aggagtattc ataaaacaag gcaaatgtaa
    11941 agaactgtat tgttttgtat aaccacatgg ttacctaatc gccaattaat ataagctcca
    12001 ttatttctcc atatttttat gttagaagtg acaaagagaa atgtaatgtt tctctcagag
    12061 aatataaatc attccttttg cccaccttaa tggtgggctt ttttatgcaa aacctgaacg
    12121 tcctgtggta ttcctctggc ataatgattt tcgcgattaa ccaacaacca gaccagcaaa
    12181 gacgccacca caagcacagt aacatccatc aggcttgcca caccccatgc gtgcggctca
    12241 aagccgccat ggcatattaa tccgcttgcc attttcgaac agctgattgg tttggtccgg
    12301 tgtttccctg cttgcactta aaaatgagcg gataggaaac tctcgaaatg gttcgtcgat
    12361 atgctcacct cgcacctaat caccttaccg aacacgcacg gtaaatagat tcgatcctga
    12421 acccatcggt cccaaatctg tcccaatcaa aaaataagga aggtattaat gatgtgtaac
    12481 ttattgattt aagtggtgcc gataatagga gtcgaaccta cgaccttcgc attacgaatt
    12541 agcgagacca gtgattcaag atgttcacag ctgtttcagc atgcaataaa aaatatataa
    12601 aaatcaacaa aatacacata aatgcagtat caagatgttt cgccttgttt ctgatgatat
    12661 catgttaaat gtgtacccca ctgtgtaccc aaaaggctga agatatgact tttactatta
    12721 cacaagacag acaattggct tcattgaccg ttactaaaga agaaaaagaa atcttatttg
    12781 ctgtaaaatc taaagctggg ggaggactct ttatacgcgt tcgttatggt agcgacaata
    12841 aaagctggat ttatcgttat cgaatagctc aaaagccagc taaattaaca ctaggtagtt
    12901 accctgccat gggattagct caagctcgta aagctcatgc ggatgcaatt gaattagtaa
    12961 gaaaaggtat agatcctcgt catattagaa aaaatgaaaa acaaaaaaat gaacaaatga
    13021 ttatttactc tgaattatgg aaagattgga tagaattcag aaagacaagt aaaccaatta
    13081 gcaccagaac ccttgcagat tatgaaggga cttatcaccg ccaccttgaa aaagcattag
    13141 gaaaccttcg cattgacgaa cttaccaaaa gcgttatttt tgaacatctc agtaatgtaa
    13201 gaaaaaccag ttctgaagca gttcgtaaag gattaattat tctaaatatg actcttgatc
    13261 atgccaactt acagggtatg cttgagcata acccagcacg actgctcaaa ccagcaatgt
    13321 ttggtgcatc gatgaataaa cctcgcgagc gatggcttcc tgagaatgaa ctccggatgc
    13381 tatggaaggc tttggatgat gctactgttg gaggaggctc cattgcatct ggtggctatg
    13441 gaatttcctc tagtgtggta ttatctcatt ctgtcgcaaa tgcactccgt ttgattattt
    13501 tcacaggagt gcgccgctct gaagcggcac aaatgcgctg ggatcaaatt aatggagagc
    13561 gttggaccat accagccact aaaaatggga aaagccatat tgttacttta catccgtata
    13621 tgctttcttt aataaaaaca caacgtgaat tcactgaagg tgcatatgtt tttggttcta
    13681 ctagcaaacc aggctttccc atcacaaatg acgctctgac tcgcgcgtta gaaagggttc
    13741 gctctaagta tctagccgaa cttactccat tttctcctca tgatctgcgt agaagtgttg
    13801 cgactggatg cgctgaatac cttgatgctc cagagcgcct aatagagtta ctgttaaatc
    13861 atgtacccaa agaccgttta atacgaacat atcaagtcgg acaacaagct gaaaaattaa
    13921 aaaatttatt tatagaatgg gggaatttta ttatgaataa cgtcattact gtgcagcaaa
    13981 atgctccgga taatgttatt catataaaat ttgggaacag
//
LOCUS       DAFGPF010000124        13865 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFGPF010000124 DAFGPF010000000
VERSION     DAFGPF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13865
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.124"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            252..1682
                     /gene="iolT1"
                     /locus_tag="LSX49_004188"
     CDS             252..1682
                     /gene="iolT1"
                     /locus_tag="LSX49_004188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015962247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol import MFS transporter IolT1"
                     /protein_id="HBL7170518.1"
                     /translation="MFTSNSRYNTGYILRICAIAALGGILFGYDTAVISGAIGSLTSY
                     FHLSPAEIGWAVSCVVVGCVIGSFSAGYLSKRFGRKKSLMVSALLFTISAVGTSLSYT
                     FTHFVIYRIIGGLAVGLAATVSPMYMSEVSPKNMRGRALSMQQFAIVFGQILIFYVNY
                     KIASIAADTWLIELGWRYMFAAGIIPCILFCILVFLIPESPRWMMMIGREEETLKILT
                     KISNEEHARHLLADIKTSLQNDQLNAHQKLNYRDGNVRFILILGCMIAILQQVTGVNV
                     MMYYAPIVLKDVTDSAQEALFQTIWIGVIQLIGSIIGAMIMDKMGRLSLMRKGTIGSI
                     IGLLLTSWALYSQATGYFALFGMLFFMIFYALSWGVGAWVLISEIFPNRMRSQGMSIS
                     VGFMWMANFLVSQFFPMINENPYLLSHFHGAFPMWIFAICCIFSYFFICRYLPETKGI
                     SLEKMESVVLAKRRKKTAANSNRTLF"
     gene            complement(2015..3019)
                     /locus_tag="LSX49_004189"
     CDS             complement(2015..3019)
                     /locus_tag="LSX49_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL7170519.1"
                     /translation="MENIALIGIDLGKNSFHIHCQDRRGKAVYRKKFTRSKLIEFLAT
                     CPATTIAMEACGGSHFMARKLEELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAAS
                     RPSMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGSAVISR
                     LSTILEDNNLPLYLSQLLLKLQQHYHYLVEQIKELESQLKRKLDEDEVGQRLLSIPCV
                     GTLTASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLL
                     VQCARVFIQKLEHQSGRLADWVRELLCRKSNFVVTCALANKLARIAWALTTRQQTYEA
                     "
     gene            complement(3259..4092)
                     /gene="iolR"
                     /locus_tag="LSX49_004190"
     CDS             complement(3259..4092)
                     /gene="iolR"
                     /locus_tag="LSX49_004190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol utilization transcriptional
                     regulator IolR"
                     /protein_id="HBL7170520.1"
                     /translation="MSKHQTQLSLLQDDIRSRYDSLSKRLKQVAQYILDNSNSVAFDT
                     VASIAQHADVPPSTLIRFANAFGFSGFNEMKRIFRQHLMEETVSYTERARLFRQKNAD
                     EGEPTPEKPGEILKLFSMVNAQVLQQLPVQIKNEQLDAAVNLLAKADNIYVIGLRRSF
                     SVASYLTYALRHLERRAFLIDGIGGMFSEQLSMVSSDDVVIAISYSPYAQEVVELVEL
                     GAKRGAHYIAITDSQVSPLAAFSEVCFVVREAQVDGFRSQVASMCLAQTLAVSLALAT
                     E"
     gene            complement(4360..4635)
                     /locus_tag="LSX49_004191"
                     /pseudo
     CDS             complement(4360..4635)
                     /locus_tag="LSX49_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313154.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
     gene            complement(4793..5600)
                     /locus_tag="LSX49_004192"
                     /pseudo
     CDS             complement(4793..5600)
                     /locus_tag="LSX49_004192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003845607.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(5826..6794)
                     /locus_tag="LSX49_004193"
     CDS             complement(5826..6794)
                     /locus_tag="LSX49_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBL7170521.1"
                     /translation="MTVSRKEKNTPTPHDAAFRAFMSSAEVARDFVELHLPAEYRQLC
                     DLSTLRLEPCTFVDQDLKQYACDALFSMKTVSGEEGYIYCLAEHQSTENAFMAFRMLR
                     YAVAAMQRHFEQHHELPLVIPLLFYHGERSPYPYSMNWLDCFRNPELAAKIYTRSFHL
                     VDVTVLDDDEIMQHRRMGALTLLMKHSRSRDLMMQMDRLVQLIQNSLNEELAQILFHY
                     LLNGSEHVTVRFLQMLAQRLPQHEGNIMTLAEQLKQSGREEGIALGLERGIAQGMAQG
                     MAQGMAQGVEQGKLETARNMLNAGINRKMVLELTGLSAEQLNMLKH"
     gene            7143..7457
                     /locus_tag="LSX49_004194"
     CDS             7143..7457
                     /locus_tag="LSX49_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170522.1"
                     /translation="MTEILRIAKTYEPMLDYWELVVQNASTIASHTATNRPSPEAIMA
                     NYQLNEQLLEGCRPWIVIFDDVLTAGSHFKAMKSLILQHIPEACILGLFVARTTRGAQ
                     II"
     gene            complement(7475..9841)
                     /locus_tag="LSX49_004195"
     CDS             complement(7475..9841)
                     /locus_tag="LSX49_004195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL7170523.1"
                     /translation="MVHKSDSDELAALRAENARLVSLLEAHGIEWRRKPPSSVQRVSV
                     LSTDEKVALFRRLFRGRDDVWALRWESKTSGKSGYSPACANEWQLGICGKPRIKCGDC
                     VHRQLIPVSDLVIYQHLAGTHTAGLYPLLEDDSCYFLAVDFDEAEWQKDASAFMRACD
                     ELGVPAVLEISRSRQGAHVWIFFASRVSAREARRLGTAVISYTCSRTRQLQLSSYDRL
                     FPNQDTMPKGGFGNLIALPLQKRPRASGGSVFVDMNFQPHPDQWAFLASVLPMNVQDI
                     EPTILRATGSIHPLDVNFINEEDLGTPWEGKKSSGNRLNLAVAEPLKITLANQIYFEK
                     AQLPQVLINRLIRLAAFPNPEFYKAQAMRMSVWNKPRVTGCAENYPQHIALPRGCLDS
                     VLSFLRDNNIAAELIDKRFAGTECNAVFMGNLRAEQEEAVSALLRYDTGVLCAPTAFG
                     KTVTAAAVIARRKVNTLILVHRTELLKQWQERLAVFLQAGDSIGIIGGGKHKPCGNID
                     IAVVQSISRHGEVEPLVRNYGQIIVDECHHIGAVSFSAILKETNARYLLGLTATPIRR
                     DGLHPIIFMYCGAIRHTASRPKESPHNLEVLTRSRFTSGHLPSDARIQDIFREIALDH
                     DRTVAIAEEAMKAFGQGRKVLVLTERTDHLDDIASVMNTLKLSPFVLHSRLSKKKRTM
                     MISGLNALPPDSPRILLSTGRLIGEGFDHPPLDTLILAMPVSWKGTLQQYAGRLHREH
                     TGKSDVRIIDFVDTAYPVLLRMWDKRQRGYKAMGYRIIAEDDEPAFSF"
     gene            complement(9996..10559)
                     /locus_tag="LSX49_004196"
     CDS             complement(9996..10559)
                     /locus_tag="LSX49_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HBL7170524.1"
                     /translation="MYNANPNYEMNFAILKDVNEHMEGLFQRFSKLLPFRIDFAYRKD
                     TPSFGHSCKHSMCIEIYRLLSETQTMLAGYYWVMEYTPDKGLHIHFIGYLDGQRHKNS
                     YQISRQLGDIWRRITEGDGYFHLCRAKDKYPVRIDHVIHYSDKSAVDDLRYALSYLAK
                     QDQKEHGIILMRSRLPEKSNRGRPRHN"
     gene            complement(11524..12957)
                     /locus_tag="LSX49_004197"
     CDS             complement(11524..12957)
                     /locus_tag="LSX49_004197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HBL7170525.1"
                     /translation="MCLLAPENPYPIYALPPLVRNAIIETQKNTQAPLAMVATSALTA
                     ISIACQNLIDVCRPGNLRGPVNLYSLILADSGERKTTVDKVFMKAFYLRDEALAEEYA
                     KLVENYSTEKEIWEQKQKALESKFHKEIRAGKDYKATESELETHLNKSPVPPQIRRTI
                     FNETTIEGMLKYYSDSNRSFALVSSEGGVIFDSRAMSKLGIINTLWDGGSLFIDRKSS
                     PGINLKEPRLTISVMIQPDVYHKGFCTRKKEIVKTSGHHARFLMCQPTSTQGTRIITG
                     DNYSSQYQDLFEERINELIDESLAMSGERRCLHFSPQAARIWTDYYNDVESKLGGLGP
                     LRHCREYAAKNAEYMARLAGLIYHSSGEEGEISPYTAEMARELAIWYGNEYVRLSNPL
                     TFDNSALTVPVRLIPEELELFNWIKSYCIEKGILCMKKNDILQRGPNRFRKKDKINWL
                     LDLLYEQNRVVPVIEGKTLCVAPNFDL"
     gene            complement(13206..13433)
                     /locus_tag="LSX49_004198"
     CDS             complement(13206..13433)
                     /locus_tag="LSX49_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HBL7170526.1"
                     /translation="MSYIKPDTPYPVYAQPSMTGNAIIETQHNEKASLAMTTTSLLTA
                     MSIACQNQIDVCNPGNLRGPVNIYTMVLADS"
     gene            complement(13539..13766)
                     /locus_tag="LSX49_004199"
     CDS             complement(13539..13766)
                     /locus_tag="LSX49_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HBL7170527.1"
                     /translation="MWLPLTDEQRLVILKAYGIECDRLVREKERYEITSISRTQAWKL
                     EREGTFPPRKSIGKKSCGWLLSDLLCWIQTR"
BASE COUNT         3739 a         3451 c         2893 g         3782 t
ORIGIN      
        1 gcagcatctt aacgataaaa aacgccagga ttatgaaatt cgaaatgtga cacccataac
       61 aaaacacaag tttcattatt gaatgttttg aaattaaaac ataggttgtg aaacaagagt
      121 tctcaatagc tataagatcg tcggcagagc tacggcaatg accgacagaa gatgaatttg
      181 tctttgtcta tttgttcact aaattcaaac agatagatat agatgaagtt tattctggag
      241 ataatctacc tatgttcaca tcaaatagtc gttataatac gggttacata ttacgcatct
      301 gcgcgattgc cgcactgggc ggaatattat ttggctacga tactgctgtt atttcaggtg
      361 cgattggttc actgaccagc tactttcatc tatctcctgc tgagatcggc tgggcggttt
      421 cctgcgttgt ggtggggtgc gttattggtt cgtttagcgc cggatattta tccaaacgtt
      481 ttggacgcaa gaaatcattg atggtttcag cgctgttatt cactatttcc gcagtgggca
      541 cctccctctc ctacacgttc acccattttg tgatttatcg cattatcggt ggactggcag
      601 tcggcctggc ggcaacagta tcaccgatgt atatgtctga agtctcaccg aaaaacatgc
      661 gcggcagagc attaagtatg cagcagtttg ctatcgtttt cggtcagatt ctgatcttct
      721 acgttaacta caaaatagca tcgattgcag cggatacctg gctcattgaa cttggctggc
      781 gctatatgtt tgctgcgggt attattccct gcattttgtt ctgtatttta gtctttttaa
      841 tcccggaatc tccccgctgg atgatgatga ttggtcgcga ggaggagacg ctaaaaatac
      901 tgaccaaaat atccaacgaa gaacatgcca gacatcttct tgccgatata aaaacctcac
      961 tgcaaaacga ccaactaaac gcccatcaaa aacttaatta ccgcgacggg aacgtgcgtt
     1021 tcatcctgat tctgggctgc atgatcgcta tactgcaaca ggtaacaggg gttaacgtca
     1081 tgatgtatta cgcgccaatc gtccttaagg atgtgaccga tagcgcccag gaggccctgt
     1141 tccagacaat ctggatcggc gtgattcagc ttatcggttc cattattggc gcaatgatta
     1201 tggataagat ggggcgtttg tcgctgatgc gtaaaggcac tattggcagc atcatcggct
     1261 tgttgctcac ctcatgggcg ctgtacagcc aggcaaccgg ttatttcgcg ctattcggta
     1321 tgctgttctt tatgattttc tacgcgcttt cctggggcgt gggtgcatgg gtgcttattt
     1381 ctgaaatatt ccctaaccgg atgaggtcgc agggaatgag tatttcggtc ggatttatgt
     1441 ggatggcaaa ctttttagtt tcgcaattct tcccgatgat taatgaaaac ccgtatttac
     1501 tttcgcattt ccacggcgca tttccaatgt ggatattcgc catctgctgc atcttcagtt
     1561 acttctttat ctgccgttac ctgccggaaa caaaaggcat ttcgctggag aaaatggaga
     1621 gcgtagtgtt agcaaaacgc agaaaaaaaa ctgcagccaa ttcaaaccga acgttattct
     1681 gattaagttt caccacaatg ccgatgatcg ctaaatacga tcatcggctt gttttttagg
     1741 gggcggtttg ggaaacggac tctatggtca ctcccgtttt tgcaacaccg attttgacga
     1801 taagtgggct tgcttgaatc tatccggcgt ctgaatggga ttttattccc gcgcctcgat
     1861 gagttccgcg cctgatgaac ctcaagaaaa tatacggctt caatgagcct ttccgtttca
     1921 caggttcctc aacaggccgg tgggccgttc gtatcatcaa taatcagtat ccgcaaaacc
     1981 agatgagtga ttgtttaaac agatataact ctcactatgc ttcgtaagtt tgctgccgtg
     2041 ttgttagtgc ccaggctatt ctggccagct tgtttgccag agcgcaagtc acgacaaagt
     2101 tacttttccg gcacagtaac tcccggaccc agtcggccaa cctgcctgac tggtgttcca
     2161 gtttttgtat aaatactctg gcgcactgaa ccagcaaggt tcgtatcttc ttgttgcctc
     2221 gcttgctgat gcccaacaat gttgtccgcc cccccgtgct gtattgtcga ggtaccaacc
     2281 ctgttgcggc ggcaaagtct cggctactgg catactgctt cccgtcgcca atctcagttg
     2341 aaatagtact tgcagttagt gttccgacac agggaatact cagtaaacgc tgacctactt
     2401 catcttcgtc cagctttcgt ttcaactggg attccagctc tttaatctgc tcaacaagat
     2461 agtgataatg ttgttgtagt ttcagtaata actggctgag ataaagaggt aaattattgt
     2521 cctcaagaat agtgctcagc cgactaataa ctgcagaacc tcgtggaacg ctgataccaa
     2581 attccagcaa aaaagcatgc atctgattag ttgtttttac cttatcctga accagggatt
     2641 ctcgaacacg atgcagagcc cgcattgcct gctgagattc cgttcggggt tgcacaaaac
     2701 gcatcgatgg acgcgacgct gcttcacaga tagcctcggc atcgacgaaa tcatttttgt
     2761 tgcttttaac gaatgggcgg acaaattgtg gtgatatcag ctttgggaaa tgtcccaatt
     2821 cttccagctt acgggccata aagtgagaac caccacaggc ttccattgcg atggttgtag
     2881 ctggacatgt cgccaaaaat tcgatcaact ttgaccgggt aaatttttta cggtaaacag
     2941 ccttcccgcg acgatcctgg caatgaatat gaaaagagtt tttacccaga tcgataccaa
     3001 tgagcgcaat gttttccatg atagttctcc gaatgaaagc ctgtcctctg catagtacca
     3061 ggaaggaggg agtgaccatc tcattaaata ttgtacggtt gcgttatcgc gctcgggtgt
     3121 actcccgtgc tatacggcgt tttcaggggc tgtggcctta atcggataac ctaaatgcga
     3181 tatagcaaga gcgataactt aaaggcgata gccactgacg ttaaatcaat acgttagttc
     3241 ccaaaccgct cccttttttt actccgtcgc cagcgccagt gaaaccgcta acgtttgcgc
     3301 cagacacatg gacgcgacct gagaacggaa accatcgacc tgcgcttcac gtaccacaaa
     3361 acagacttca ctgaacgctg ccagcgggct gacctggcta tcggttatcg caatatagtg
     3421 cgcaccgcgt ttcgcgccaa gctcgactaa ttccaccact tcctgcgcgt aaggcgagta
     3481 gctgatggca ataacgacat cgtcggagct gaccatactt agctgttcag agaacattcc
     3541 gccaataccg tcaattaaaa atgcccgtct ctccagatga cgcaatgcgt aggttaaata
     3601 actggccacg ctaaacgaac gacgtaatcc aatcacataa atattgtcag ctttcgctaa
     3661 cagatttacc gccgcatcca actgctcatt tttaatctgc accggtaatt gttgtaatac
     3721 ctgtgcattc accattgaaa atagcttcag aatttcaccc ggcttttccg gggtaggttc
     3781 cccttcatcc gcatttttct gtctgaacag acgcgcccgc tcggtatagc ttactgtttc
     3841 ctccatcagg tgctggcgaa atatccgttt catttcatta aatccgctaa aaccaaacgc
     3901 attagcaaaa cgaatcagtg tcgaaggggg aacatcggca tgttgcgcga tggaagcgac
     3961 cgtatcaaaa gcaacgctat tactgttatc cagtatatac tgagcaactt gtttaagacg
     4021 tttgctaagg ctatcatagc gactgcggat atcatcctgc agtaaggaaa gttgagtttg
     4081 atgtttagac atgcatgata ctctaatgga acgaaaattt cggaaataac catattatca
     4141 caaatgaact gaacatacag ttaagttgaa tcggcaactg attacccaac tactctttaa
     4201 ccatcatcca ggtattctcc ggccctatgg ataaatgccg ttaaaaatgc gtttgtgggc
     4261 ttctttcagg cgctgtttgt cgaaaggacc aatgataggg ctttcttcca gctacgataa
     4321 gttaagttaa gttaagcgaa cgccgtattg acgtttacga tcggtggaga atccgggcgc
     4381 accgacaaac tcatcttgcg aggtaattac ctgacgcaaa agcggatcgt ccggattgcc
     4441 tttctccatg cgatcgataa atgctcgggg cacacgcagg gcaaacagct ttttggcgct
     4501 gcgtccggcc aacagttttt cgtccgcgtc tatattcaaa agacgcagaa gttcatcagg
     4561 aacggtcaca acatcggcaa gttgcgttaa ccaatcatct cttgatgggg tatttagggt
     4621 tacaatatac gtcattttgt gacttaacca ctaattaaca aatttcagag gattttatgg
     4681 caaagtacta tagcaacgat tttcattcta gtctgcccat tctggcgttg aatgaggaca
     4741 atcaacaatt aaagtcgtaa tttcatccaa acggaattct ggccacttcc acttattccc
     4801 cataacccaa cgcctccaga tcctggcgaa tcgcacgatc cagttcatcc acctgcttca
     4861 tctgctcaaa caacgtcttc gacaaatcct gcattttcgt ctcaaatgcc actccgtctt
     4921 cttcctgccc ggctgcacac acatagcggc ccggtgtcag tatgtagtcg ttatctttaa
     4981 tatcaagcag ggtcgcaact ttgcagaagc ccgcttggtc ttcatatttt tccagcttgc
     5041 tgtcaccacg cgcaatccgt gcagccagtt cttctggcgt gctgcgccag cgcatgatag
     5101 gtatcggcga tggtggcaat atcttccgtc gttaactctt tagttgtgcg gctaatcatg
     5161 gtgccgaagt tacgcgcatc aataaacagc gtctcgccct gacgatcacg ataacctgtg
     5221 gccgggtcgg caaccttcga tttggtcata aaccataaac acacctagat ctgcgtggtg
     5281 taaaacaact gacctggcag agtgatcatg cagtcgatca gatcattttc gatcatctgt
     5341 gcacggatct cgccttcacc gctggtgtta gaactcatcg aaccgtttgc cagcacaaaa
     5401 cctgctgtgt cgttagccga cagtctggag agcatatgca aaatccaacc gtagttagcg
     5461 ttatcggtag gcggcatacg ataaccagca aaacgtgggt ctttggttaa ttcggcttca
     5521 ttacgccagt ctttcaggtt gaacggcggg ttcgccagaa tgtagtcggc tttcaggtcc
     5581 gggtgctggt cgctgaagaa gtacgatatg ccaaaatggt tgaaacgtac cacatcagta
     5641 tggtaacaag gaaatatgtc tatgacgtcg tgaattcccc cggatttata ttcctgcagg
     5701 gccggatagc ggtcttacaa atgaacactc caaaatattc agaggtgccc cctgttctga
     5761 gcaatataat gaagccacca ccgcctgcta caggagagca ggaagtgtca cccgacaaca
     5821 tacagtcaat gcttcagcat gttgagttgc tcagctgaaa gcccggttag ctccagtacc
     5881 atcttccggt ttatcccggc attcagcata ttgcgggcag tttccagctt accttgttca
     5941 acgccctgcg ccattccctg cgccattccc tgcgccattc cctgagcaat accacgctcc
     6001 agccccagcg caatgccttc ctcacgcccg ctctgcttca gttgttctgc cagtgtcata
     6061 atattgccct cgtgctgtgg cagacgctgc gccagcatct gcaaaaacct taccgtcaca
     6121 tgttcactgc cgttcagcag atagtggaac aggatctgcg ccagttcttc attcagcgag
     6181 ttctgtatca gttgaaccag cctgtccatc tgcatcatga ggtcccggct gcggctgtgt
     6241 ttcatcaaca gcgtcagagc ccccatacgc cggtgctgca ttatctcgtc gtcatccagc
     6301 accgtcacgt ccaccagatg aaacgatctg gtgtagattt tagcagcaag ttccggattt
     6361 ctgaaacagt ccagccagtt catgctgtac gggtacggac tccgctctcc gtgatagaac
     6421 aacagcggga tcaccagcgg cagctcatgg tgctgttcaa aatggcgctg catcgccgcc
     6481 accgcatatc tgagcattct gaatgccata aatgcgtttt ccgtgctctg gtgttccgcg
     6541 aggcaataaa tatacccctc ttcaccactg acggtcttca tactgaacag cgcatcacac
     6601 gcatactgtt tcagatcctg atccacaaag gtacagggct ccagccgcag cgtcgacaga
     6661 tcacacaact gccggtattc cgccggaaga tgtaactcaa caaaatcgcg ggccacctcc
     6721 gctgaggaca taaatgccct gaaggcggca tcatgcggcg tgggcgtatt tttctctttt
     6781 ctgctcaccg tcatccactt cacaatcccg ggtccctgtt tttaatgata ccagccaccg
     6841 ccgtttccgt caccggataa accctgaccc agaagtgtgc acgggtaaca cctgatgcct
     6901 cagcggaaga gacctgccac cacaggacgt gtcaacgacc ggagcgtgct ctttaacgcc
     6961 gtgaacggtt cactctctcc tgacgtcgcc gtacgcatca atctgtaaca cccttccacc
     7021 gtgcaatgtc cctctggact gagggcgtcc catgtctgtt gcagtaacgc caccaggtgc
     7081 gaatccgcgt catcagctgt aatccgggta ccaaggggat acatgccgct tacgatgacc
     7141 gtatgacaga aattctgcga attgcgaaaa cctacgagcc catgctggat tactgggaac
     7201 tggttgtgca aaacgcatca acaattgcct ctcatacagc aacaaatcgc ccctcaccag
     7261 aagcgattat ggcaaactac caactgaatg aacaattact ggagggatgc agaccctgga
     7321 ttgttatttt tgatgacgtt cttactgccg gtagtcattt taaagcgatg aaaagcctga
     7381 tactacaaca tattccggaa gcctgtatac tggggctctt tgttgcccgt acaactcggg
     7441 gagctcaaat tatttaaaaa gagtaaagta ttccttaaaa tgaaaacgct ggttcatcat
     7501 cctcagctat aattctgtac cccatcgctt tataaccccg ctgacgttta tcccacattc
     7561 tgagcagcac aggatacgca gtgtccacaa aatcaatgat cctgacatca cttttaccgg
     7621 tatgctctct gtgtagacgt cccgcatact gctgtaacgt ccctttccat gacacaggca
     7681 tggcaagaat cagcgtatcc agcggagggt ggtcaaatcc ctcaccaata agtctgcctg
     7741 ttgacaacaa aatacgggga gaatcaggag gaagagcatt cagcccggaa atcatcatag
     7801 tacgcttttt tttcgataat cgactatgga gaacaaaagg cgacaatttc agtgtgttca
     7861 tcactgaggc tatatcatcc agatgatctg tacgttcagt cagtaccaga actttacgcc
     7921 cctgcccaaa agctttcatg gcttcttcag ctatcgccac cgttctgtca tgatccagag
     7981 caatttctct gaaaatatcc tggattctcg catccgatgg taaatgacca gatgtaaaac
     8041 gggaacgggt cagcacctcc agattatgtg ggctttcctt cgggcgggac gctgtatggc
     8101 gaatggcacc acagtacata aaaataatgg ggtgcagacc atcccgtcgg attggtgttg
     8161 ccgtcaggcc aagcagatat ctggcattcg tttccttcag aatcgcagaa aatgaaaccg
     8221 cgccaatatg atggcactca tccacaatga tttgcccata attcctgacc agaggttcaa
     8281 cttctccgtg tctggatatg gactgcacca ccgcaatatc aatattgcca cagggtttat
     8341 gtttacctcc cccgataata ccaatactgt caccggcctg cagaaacacc gcgagacgct
     8401 cctgccactg cttcagcaat tcagtccggt gtaccagtat cagtgtattc actttccgtc
     8461 tggcaatcac tgccgctgcg gtaactgtct taccaaaagc cgttggcgca caaagcacac
     8521 cagtgtcata acggagtaat gccgaaacgg cctcttcctg ctccgctctg aggtttccca
     8581 taaaaacggc attacattcc gtcccggcaa atcgtttatc gattaattct gcagcaatat
     8641 tgttgtccct aaggaaagat aatacgctgt ccagacatcc ccggggcaac gcaatgtgtt
     8701 gcgggtaatt ctccgcacaa cctgtaacac ggggcttatt ccagactgac atacgcattg
     8761 cctgagcctt ataaaactca gggttcggaa atgctgccag ccgaataagt cggttaatca
     8821 gcacctgagg taattgcgct ttttcgaaat agatctgatt tgccagcgtg attttcagcg
     8881 gttcagcaac agcaagattc agtctgtttc ctgatgattt tttcccttcc catggcgtac
     8941 ccaggtcttc ttcgttgata aagttcacat ccagaggatg gatacttcct gtagcccgta
     9001 atatcgtcgg ttcaatatcc tgcacattca tcgggagcac cgacgcaaga aaagcccact
     9061 gatcaggatg aggctggaaa ttcatatcaa caaaaacact tccccccgat gcacgcggtc
     9121 ttttttgcag aggtaacgcg ataagattac caaatcctcc ttttggcatc gtatcctgat
     9181 taggaaataa tcggtcataa gaactcaatt gcagctgtcg ggtccggctg cacgtatagc
     9241 taataacagc agtccccaga cggcgagctt cgcgggccga aactcgtgaa gcaaaaaata
     9301 tccagacatg cgctccctga cgtgagcggg atatttccag cacagcgggt acacccagct
     9361 catcacaggc tcgcatgaac gcggatgcat ccttctgcca ttcagcttca tcaaaatcaa
     9421 cagccagaaa ataacaggaa tcatcttcca gcaacggata taacccggca gtatgcgtgc
     9481 ctgccagatg ctggtagatg acaagatcag atacaggaat caactgacgg tgaacgcagt
     9541 ccccacattt tatccggggc ttaccgcata ttcccaactg ccattcgtta gcgcaggccg
     9601 gcgagtaccc tgatttgccg ctggttttac tttcccatct aagtgcccat acatcatcac
     9661 gcccacgaaa caaccgacga aataatgcaa ccttctcgtc ggtggataat acggaaacgc
     9721 gctgcacaga gctcggaggt ttacgtcgcc attcaatccc atgagcttca agtaatgaga
     9781 ccagacgggc attttctgcc ctcaatgcag ctaattcatc gctgtcagat ttatgaacca
     9841 tattcgttac ctgtatccga tccactgagg caccacggca gaaattcggg tcccctacac
     9901 tgatgacaaa gcgccccgcc ctcttctgcc tattaactca agcacctccc aacaacttac
     9961 aggaacttaa ttctaatacc taatacagct gtaattcagt tgtgtcgtgg tcggccgcgg
    10021 ttactttttt cgggaagcct gctacgcatc agaataatac cgtgttcttt ctgatcctgt
    10081 ttagccaggt agctgagggc gtaacgtaag tcgtctaccg cagatttatc actatagtga
    10141 atcacgtgat cgatacgcac cgggtatttg tctttagccc ggcacaggtg aaagtaacca
    10201 tccccttccg tgatccgcct ccagatatct cccagttgcc tggatatctg ataagagttc
    10261 ttgtgacgtt gcccatccag atagccgata aaatgaatat gaagcccttt gtctggtgta
    10321 tattccataa cccagtaata tcctgccaac atcgtttggg tttcactaag taaacggtat
    10381 atttcaatac acatactgtg cttacaggaa tgcccgaaac tgggcgtgtc tttcctgtag
    10441 gcaaaatcaa ttctgaaagg taacagttta gaaaaacgtt gaaacagacc ttccatgtgt
    10501 tcattcacat ctttcagaat cgcgaaattc atttcgtaat tgggattagc attatacatt
    10561 ttatagtcct tactttataa aactgacagg aaagtggaat tacataaata ctgagagtac
    10621 agaaacgccg taccgcggca ttaataaacg aggtaaccag cagcacagac aacctgataa
    10681 aactgtttcg tattacctca ttacagtaat agggtaatga ttcagaatac agtaagactc
    10741 tcttaaactg aggaccagaa cgaattacaa taaaaaacac acctcatata attgagttta
    10801 aggaagcacc attcaattac ttacaggaaa taatctgatc ttcacaaaag tcagcattga
    10861 atagccgcag gcaacatcgc tattagtatt gccgtaccat taagtaaaaa cagagactct
    10921 gcagagagag cctacagata tttaatctca caataagaag attatttcat acagaaaaga
    10981 ttatatttac ccataaactg taacggagct ataacgtacg aactaaagac aatacactct
    11041 aatagtgttc tggtacgtaa ctagtgttaa atacaaacca gacatacatt cagtggatta
    11101 actttctcaa tattacgcta taagtgtagt aacataattt acacataact aaactccaca
    11161 caccaccaca ctgtagtgta tggagatata tgtattacgc acatacagaa tacttagcat
    11221 aaagaggagt gatattacga tagaaagaga caacataaca gataacataa ctcccattaa
    11281 taatactaat taacctaaat tatttattga acacgaaaac aatgaaggtc ccacctcacc
    11341 tcagactaaa accgacaata tcctgagcaa cactctatcc aatagtaaat agtggttaca
    11401 ccagttatat ttactgactg acctgtacca gagttttcta atacaacaat gctgacatgg
    11461 taaaggcatt agtctcctcc gcaagtagca gaggagacta tatgtactca acgattaagt
    11521 cgttcagagg tcaaagttag gtgcgacaca caacgttttt ccctcaataa ccggtacaac
    11581 tctgttttgt tcatacagta aatccagtaa ccagttgatt ttatcctttt tccggaaacg
    11641 gttcggacca cgctgtaaaa tgtcattttt tttcatacag aggatcccct tctcaataca
    11701 atagcttttt atccagttga aaagttcaag ctcctctgga atgagtcgca caggtacggt
    11761 cagggcagag ttgtcaaaag ttaacggatt agacaaccgc acatactcat taccgtacca
    11821 tattgctaat tctctcgcca tttctgcagt gtaaggggaa atctccccct cttcaccgct
    11881 cgaatggtaa ataagtcctg ccagtcttgc catatactct gcatttttag cagcatattc
    11941 ccggcaatgt cttaaaggcc ccaatccccc cagcttcgat tccacatcat tgtaataatc
    12001 cgtccagatt ctggcagcct gaggagaaaa gtgaaggcaa cgtcgttcac cactcatcgc
    12061 cagactttca tcaataagct cattgatcct ctcttcaaac aaatcctgat actgtgatga
    12121 ataattatct ccggttatta tccttgtccc ctgcgttgat gttggttgac acatcaaaaa
    12181 ccttgcatga tgtcctgacg ttttcacaat ttcttttttt cgcgtacaaa aacctttgtg
    12241 gtaaacatca ggctgaatca tcaccgatat cgtcagtctt ggctccttca aattaattcc
    12301 gggagatgat ttcctgtcga tgaaaagaga accaccatcc cacaaagtgt taataattcc
    12361 cagtttactc atggcccggc tgtcaaaaat taccccccct tcactggata caagagcaaa
    12421 agagcgattg ctatcggagt aatattttaa cattccctct atcgttgtct cattaaaaat
    12481 tgttcgacgt atctgcggcg gaacaggaga cttattcaga tgcgtttcaa gctctgattc
    12541 tgttgccttg taatctttac cggcacgaat ctctttatga aattttgatt ccagcgcttt
    12601 ttgtttttgc tcccatattt ccttttctgt gctgtaattc tcaaccagtt tcgcgtattc
    12661 ttccgccagg gcttcatccc tgagataaaa tgctttcata aacactttat ccacggtcgt
    12721 tttcctttca ccagaatcag ccagaatcag agagtaaaga ttaacaggcc cacgtaaatt
    12781 tccaggtctg cacacgtcaa tcagattctg acaggcaatt gagatcgctg ttaatgcgga
    12841 tgtcgccacc atagccaaag gtgcctgtgt atttttttga gtttcaatta ttgcatttct
    12901 caccagcggt ggtagtgcat atatcggata aggattttct ggtgcaagta agcacataaa
    12961 agcctctctt ttcattaatg ggttagtaaa gtagcagcaa ctcccgctat aatagcgaaa
    13021 tagctgctgt tcagacctaa tgttctgaga aatacagaat atctgtagat ctgatgttta
    13081 ataaaccgat aaggttaatt cagttcatac tgtgttattt accacgaaat atcattcatg
    13141 tttctcattc ttaacacctc ctaaaattat ttcactaaca ccttcccccc ggtctttttc
    13201 ctttctcagg aatcagccag aaccatagtg taaatattaa cgggcccacg taaatttccg
    13261 gggttgcaca cgtcaatctg attctgacag gcaattgaca tcgctgttaa taatgatgtt
    13321 gtagtcatag ccagagatgc tttttcattg tgttgagttt caattattgc atttccagtc
    13381 attgatggtt gcgcatatac tggatacgga gtatccggtt tgatgtaaga cataaatatt
    13441 tccttttttc gtaataactt tcggttatag cagctatttc cgctacaata gcaacaatag
    13501 ctgctataca gactggatat actgaaaata cagacagttc atctggtctg tatccagcag
    13561 agaaggtcac ttaacaacca tccgcaagat ttctttccga tagacttacg tggtggaaat
    13621 gttccctccc gttcaagttt ccacgcttgt gtacgagaaa ttgacgtgat ctcatatcgt
    13681 tccttttcac gtaccagtct gtcgcattca atcccataag ctttcaaaat gaccagacgc
    13741 tgttcatctg ttaatggaag ccacatacta ccctcctgat atatcaatac tttttatttc
    13801 cggcatgagc atgaaatgac taaatttccc ggataaacaa tgagtgaaag tcactatcat
    13861 tcatc
//
LOCUS       DAFGPF010000125        13693 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFGPF010000125 DAFGPF010000000
VERSION     DAFGPF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13693
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.125"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..267)
                     /locus_tag="LSX49_004200"
     CDS             complement(<1..267)
                     /locus_tag="LSX49_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL7170528.1"
                     /translation="MSRKTQRYSKKFKAEAVRTVLENQLSISEGASRLSLPEGTLGQW
                     VTAARKGLGTPGSRTVAELESEILQLRKALNEARLERDILKKATV"
     gene            334..1118
                     /locus_tag="LSX49_004201"
                     /pseudo
     CDS             334..1118
                     /locus_tag="LSX49_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEc52 family transposase"
     gene            1201..1458
                     /locus_tag="LSX49_004202"
     CDS             1201..1458
                     /locus_tag="LSX49_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170529.1"
                     /translation="MTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFP
                     LAKKGEGRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV"
     gene            complement(2015..2782)
                     /gene="fecE"
                     /locus_tag="LSX49_004203"
     CDS             complement(2015..2782)
                     /gene="fecE"
                     /locus_tag="LSX49_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="HBL7170530.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(2783..3739)
                     /gene="fecD"
                     /locus_tag="LSX49_004204"
     CDS             complement(2783..3739)
                     /gene="fecD"
                     /locus_tag="LSX49_004204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease
                     subunit FecD"
                     /protein_id="HBL7170531.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            complement(3736..4734)
                     /gene="fecC"
                     /locus_tag="LSX49_004205"
     CDS             complement(3736..4734)
                     /gene="fecC"
                     /locus_tag="LSX49_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="HBL7170532.1"
                     /translation="MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            complement(4731..5633)
                     /gene="fecB"
                     /locus_tag="LSX49_004206"
     CDS             complement(4731..5633)
                     /gene="fecB"
                     /locus_tag="LSX49_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="HBL7170533.1"
                     /translation="MLAFIRFVFAGLLLVISHAFAATVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            complement(5678..8002)
                     /gene="fecA"
                     /locus_tag="LSX49_004207"
     CDS             complement(5678..8002)
                     /gene="fecA"
                     /locus_tag="LSX49_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate transport protein FecA"
                     /protein_id="HBL7170534.1"
                     /translation="MTPLRVFRKTTPLVNAIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLTSRSTVLMDGIPVPFAPYGQPQLSLAPVS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYVNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            complement(8089..9042)
                     /gene="fecR"
                     /locus_tag="LSX49_004208"
     CDS             complement(8089..9042)
                     /gene="fecR"
                     /locus_tag="LSX49_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fec operon regulator FecR"
                     /protein_id="HBL7170535.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSE
                     TGEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRILTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            complement(9039..9560)
                     /gene="fecI"
                     /locus_tag="LSX49_004209"
     CDS             complement(9039..9560)
                     /gene="fecI"
                     /locus_tag="LSX49_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="HBL7170536.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
     gene            9852..10549
                     /locus_tag="LSX49_004210"
                     /pseudo
     CDS             9852..10549
                     /locus_tag="LSX49_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558153.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(10709..10840)
                     /locus_tag="LSX49_004211"
                     /pseudo
     CDS             complement(10709..10840)
                     /locus_tag="LSX49_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11122..12480
                     /locus_tag="LSX49_004212"
     CDS             11122..12480
                     /locus_tag="LSX49_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase-like activity of phytase family
                     protein"
                     /protein_id="HBL7170537.1"
                     /translation="MKRKIIPVLIGCTLSFSALAAQPTAERYVVSFPEGTHVNYAGAF
                     ASAFPNGLPVGIGSGLLFTGKQGDALTFATITDRGPNADSPKEGKNETKIFVTPDFAP
                     LLMTIRVQNGKAEAIDPRPLHDDKGAINGLPLASDVIGSTNEVAFSDTLHRLKGDNRG
                     LDTEGITPDGKGGYWLCDEYGPFLINIDSKGKILAIHGPQAAEGEKAIAGGLPNILKW
                     RQANRGFEGLTRMPDGRIIVAVQSTLDIDAKSKKKALFTRLVSFDPASGKTAMYGYPI
                     DSAAYSKNSDAKIGDIVALDNQHILLIEQGRDKNNRMRNLIYEVDLNKASDLSGFDKP
                     GEYPEFDDEKTLSQRGITLAQKTQVVDLRSLGWQQEKAEGLALIDSKTLAVANDNDFG
                     VKVAMQHPVEGKTFKDYRVNAEGKLTLDDKQVETTLRVKPLEKPESDSELWIVTLPEA
                     LK"
     gene            complement(12719..>13693)
                     /locus_tag="LSX49_004213"
     CDS             complement(12719..>13693)
                     /locus_tag="LSX49_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL7170538.1"
                     /translation="LELMRSAFRVIRTVREKHACTQCDAIVQAPAPSRPIERGIAGPG
                     LLARVLTSKYAEHTPLYCQSEIYGRQGVELSRSLLSGWVDACCRLLSPLEEALHGYVM
                     TDGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHP
                     QTHLACFSGVLQADAYAGFNELYRNGGITEAACWAHARRKIHDVHVRIPSALTEEALE
                     QIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKTLFFGSGHGGERGA
                     LLYSLIGTCKLNDVDPESYLRHVPGVIADWPVNRVSELLPWRIALPAE"
BASE COUNT         3116 a         3711 c         3833 g         3033 t
ORIGIN      
        1 tacagttgct ttttttaata tatctcgctc aaggcgagct tcatttaacg ccttacgcag
       61 ttgcagaatt tcagattcca gttcagccac cgtgcgggaa ccaggagtac cgagcccttt
      121 tctggcggcg gtaacccatt gtcctaaagt gccttcagga agagataatc gggaagcgcc
      181 ttcactgatc gaaagttgat tttcaagaac cgttctgaca gcttcggctt tgaacttttt
      241 agagtaacgt tgggtttttc tgctcattat tagctccttc tgatgccatt ctatttcagg
      301 aaggagtgtc cgttaaactc aggctacctc aggaaaaacc gtcctgaaaa accagacggc
      361 agacgggctg tattacgcag tcaggtactt gagctacatg gcatcagcca cggttcggcc
      421 ggagcaagaa gcatcgccac aatggcaacc cagagaggct accagatggg gcgctggctt
      481 gctggcagac tcatgaaaga gctggggctg gtcagctgtc agcagccgac ttaccggtat
      541 aaacgtggtg gtcatgaaca tgttgctatc cctaactacc ttgaacggca gttcgccgtg
      601 accgagccaa atcaggtgtg gtgcggtgat gtgacctata tctggacggg taagcgctgg
      661 gcgtacctcg ccgttgttct cgacctgttc gcaagaaaac cagtgggctg ggccatgtcg
      721 ttctcgccgg acagcaggct taccatgaaa gcactggaaa tggcatggga aacccgtggt
      781 aagcccgtcg gggtgatgtt ccaagcgatc aaggcagtca ttatacgagc aggcagttcc
      841 ggcagttact gtggcgatac cggatcaggc agagtatgag tcggcgtgga aactgctggg
      901 ataacagccc aatggagcgc ttcttcagga gtctgaagaa cgaatgggtg ccagcgacgg
      961 gctatgtaag cttcagcgat gcagctcacg caataacgga ctatatcgtt ggatattaca
     1021 gcgcactaag accgcacgaa tataatggtg ggttaccacc aaacgaatca gaaaaccgat
     1081 actggaaaaa ctctaacgcg gaggccagtt ttagttgacc acaacagact acctgaaggg
     1141 agccgcggtc gcctggcagt tgcagtagca ggagatcatc cagccgcagt acaggtcacg
     1201 atgactctgg ttaatgatac cggctttgac cccgtatttt ccggctctat cgctgaatca
     1261 tggcgtcagc agccgtgcac accatcctat tgttgtgact gggaggctgc caccatgctt
     1321 cgcgctttcc ctctggcgaa aaagggagaa ggacgggccc gtctgccttc actttatgcc
     1381 agcttcggta agctgggtga gacaccgact catgaagata tcattgataa caatcgatcc
     1441 atcaactggc ctgtataacg tggctgccgg tgattaagaa agctgcacct acctaagtag
     1501 tagcaaacgc acacttttta gaaaaatcga tggtcagaaa ctggattagc aattccgttc
     1561 cagggttgct tttgatttac gttggcgtct gatcattgat ttatcctcaa aagcccaacc
     1621 tcattggtaa tgaaccagct ccgtgaatgt ccgctctggc acagagcgaa attttttgat
     1681 ctcccccctg aaatctaaac ttagtcatgt cacgtttttg ggtttctaaa attttaactt
     1741 cgcgtttttc gttgccgtaa gggttataca gaaatgtccg ttaagcagag ttcaaaattg
     1801 attgccgtga tcacgactgg tttgaaagcc gcgcccaagc ctgtacagct ctggtttgcg
     1861 ttgattatga acctgtcagc ctaaagcaag cggatggacg atgagtattg gtaatctttc
     1921 agagtccgga aaagttcagc cccagtctga acaggcttgc tggcgccagt ccagtttcat
     1981 tcagtcgtgg tttggttctt acggcctgtg caatctacct cattaggcac atcggcctgc
     2041 cagataccgg ctcggggtgt atttccgctt ccacgctgaa tactgttctc agcaatcctg
     2101 gggtcatcac ctcttctggt gtgccttgcg ccataacatg tccgtttgcc attaccacca
     2161 gttgatcgca gtaccggcta gcctgattaa ggtcgtgcag cacagcgacc accgttttcc
     2221 cctgagtccg gagttcgccc atcaaccgca tcaggtccac ctggtgattg atatcaagat
     2281 aggtggttgg ctcatcaagt aatacaacgg gcgtattctg ggccaggacc attgccagaa
     2341 atgcgcgctg gcgctgaccg ccggaaagct cggttaaccg acgaacggca agatgattga
     2401 tccgggtctg gttcatggcg acattaactc gtgcattgtc ttcagcggag agacgccccc
     2461 agagtgacag ccagggatta cgaccatacg aaaccagctc ctggactgtg atcccctctg
     2521 gcgttaaatg gtgctgaggc agcagcgaaa gcctgcgggc caactggcgc gatgagagca
     2581 tatttatggg attatcgccg agaaatacgg tgccagactg cggcattaaa agccgcgaaa
     2641 aacagtttaa cagcgtcgat ttcccgcaac cgttaggacc gatcagggcg gtgatcttcc
     2701 ccgttggcag tgagagtgaa acgtcgttaa gtaccttgtc tgtcccgtaa ctgaccgtca
     2761 gattttcagt tcgtaaagtc atttatcgca ttctcacaag caaccagaca aaccacggcg
     2821 caccgataat ggcggtcagc acgccaaccg ggagctccag tgggggatga ataattctcg
     2881 ccagcagatc ggcaaccacc aacagcaacg cacctgtcag ggccgaaaca ggcagcagtc
     2941 tgcggtgacg tccaccggtg atgctacgca tcatatgcgg caccacgaga ccaataaagc
     3001 taatcgggcc gcaggcggcc acgccggtag atgtcatggc gacagctagt aacaaagccc
     3061 agaatcgggt atggggcacc gacacaccga gcgtggtggc gcgcgcatcg ccgagtgcaa
     3121 ggaggtcgag atcgcggcaa aaactcaggc tcagcggcag aaataaaatc atcagcggga
     3181 tggcaatctt cacaaagctc cagtcacggc cccataagct gccggtcagc cacagcaggg
     3241 cgttgttcac atcctgcggg cgcgagagca tcagataatc cgtcaggctg gcccagcatg
     3301 cagaaagcgc cacgccggtg agcgccagct tcatcggctg gtgggtcttt gccagcatct
     3361 tcagcaatat caaccccgcc atgccgcccg caaaggccag cagcggcagc accatcacgg
     3421 gcagtgacgg cataagaagt agagccccca cagaggccag gctggcggca tggttaacac
     3481 cgagaatatc cggtgatgcc agagggttgc gcacaatccc ctgtatcagc acgcccgcca
     3541 cggcgagggc tgcaccgaca aacagtgcca gcagcaagcg cggcagtcgg tactccatca
     3601 atacataata atgctcgcgt ccggcctgcc agtcggtcag cagcgcgcgc cacggcacgg
     3661 ggatcactcc catatggagt gataacagcg cacagcccgc cagggcaagg gtgatgaaaa
     3721 taaccagcgc aattttcatc ctcgcctcct cacaagccag acaaagcaag ggctgccaat
     3781 cagcgccagc actgcgcctg cgggcagatc tccggggaag gccagtgcgc gtgcgagtac
     3841 atctgccagc agcatcagcg tggcccccag cagcatgctc actggcagta cgttgcgctg
     3901 atcgaagcct gcccagaagc gcgccagatg tggcaccagc agaccgataa acgccaccgg
     3961 acctgccacg ctgacgcacg caccaaccag aagcagcact aacatattga tgaccaaacg
     4021 tagcctcgtc aggttcactc ccagcgtatg ggcggtgctg tcgctgaggt tgagcaggtt
     4081 cagttgattc gccagcagca acacgacagg gactgcagtg accaccaccg gcaagagctg
     4141 ccagacatcc tgccagcggg cgtgggacac tccgcctgcc agccagtaaa agatgccgta
     4201 agcatgatct tcggccagca gcagggtgat gcgggtaagg cccatacaaa aggccgacag
     4261 cgcgataccc gcgaggatca gtttgtttct gtcatgggta tgacgaaatc cgcctcctgc
     4321 ggtcatgacc agcagccagc tcacgccgcc cccgcatgcc gcgatgaacg acagagaata
     4381 gcctgcaatc ggcgtcggac tcagcgcgct ggtaagcgcc atagccagcg ccgcgccgct
     4441 gttaatgccg agcagtgaag gagaggccat tgggttgtgg gtcagggttt gcagcagcgt
     4501 gcccgcgagc gccaggcttg cgccgatcag aacggcgacc aggcttcgtg gcaaacgaag
     4561 gttttgcacc agcgcttctg gtagcgttgg cgtgtgtcca ggcagcaggg cgcgggttgc
     4621 atctgctccg gaaacaggaa tggccgagta gcaaaacaga ctcagccaga aaataataat
     4681 aagtgctgca acgggaagcc cccacagcag caccgggtgt tttatcgcgg tcatttcaca
     4741 acggtaagcg gctgatggtg gaagattttt accgtgtcag cggcaatacg ctctgcagca
     4801 aaaataccgc gcatccgcgc ccaggtgtta ctgtcgaccg aagcaacctg ctgcttctgc
     4861 gcggcggtta acatctgcca gagcggatct tgttgccagc gtttaacaat gctctcttcg
     4921 cgatagtggg caaccagcag ccaggcagga ttgaccgcca gcagttgctc caggccgatg
     4981 gacggcatgg acgcacccgc catcgcagcg ggaacgttca gccccagaga ggccagcacg
     5041 ctgccggtcc aggtctcctg agtatgcagg ttgaattgct gttcgcgtga tgtgccaaag
     5101 gccacgcgtg tccctttggg aagctggctg gcccactgcg ccatcctctc tttatgttgt
     5161 tccaggcgtg cctgcatctc tcgcttttta cccaccattt cgccgatgat agccgcagat
     5221 tgcaaatttt cagcgtaggt ttcgttgcgg gacttaagca gcagtaccgg cgcgatttgc
     5281 tgcaaggcga tgtaaacccc cgcatggcga ctgctgtcgg caatgatcag gtctggtttc
     5341 agagcggcaa tggcttccag gctcggctgc gcgcgcgttc cgacggactg ccacggtttc
     5401 aggtgcgcac gcacttcggg caggatgcgt tttgcatcgt tatcgtcggc aataccgatc
     5461 gggctgacgt ccacggcggc cagcgcatcg gcgaacgaga gttccagcac cacaatccgt
     5521 tgtggcgttt tttcgagtgt aaacgtgccg tgttcgtcct gaaccgtggc ggcaaaggcg
     5581 tggctgatca ccagcagcag gcctgcaaaa acaaaacgga taaatgccaa cataatcaca
     5641 ttccagctaa aagcccggca agccgggcgt taacacatca gaacttcaac gacccctgca
     5701 tatacagcgt gcgcggctgg cctgcataga tgcctttgtt gttgtcgtca taagagcgga
     5761 tgaagtagtc ctggtcgaag atgtttttca caccgaatgc caggttcaga tctgccatct
     5821 gcgggccaaa gtcatacgcc acgcgtgcgc cccagagcat gaagccggga atgcggccgg
     5881 tactgccgtc ggcgctctct ttcaccgtat tggcgttatc cgcaaactgg ctggactgga
     5941 aatcgctgtt cagattgaac gtccagtttc ctggcttgta gtccacgccc agcgtgcctt
     6001 tatgtttcgg ggagaatggt accagattgc cgtaggtgtc gcctttctcg cggatttccg
     6061 cgttcacata cgcatagctg gcgtagatgg aaacgttatc aagcgttggc gttagcgtac
     6121 ccagatcgta acgtgcctgc gtttccagcc cggtatggcg cgttttgcca cgtgcagtga
     6181 cggtgtcgtt ggtctggttg gagtcgtact gattgttaaa gttaatcagg aacagcccca
     6241 tttccgccgt cagcgcgccg tcgtcgtagc gggtaccgag ttcccaggtt cgcgcttttt
     6301 ccggttccac attgccgctt tgcacagcct tgccaatctg gctgtactgt acggtgccga
     6361 acgagccttc agtgtttgca taaagattcc agctgtcagt caggtgatag agcacgttca
     6421 acgccggaag cggtgcgtta tagctcactt cttcgtgcgt gcctgtgatg gcgttgttct
     6481 ggtatgactc gatatgttcg aaacgcatac ccggcgtgat ggtccagttg ccgatgtcga
     6541 ttttgtcatc cagataccag gcgtgcgcct cggtgccgga acgcgtatcg cggtcgtaag
     6601 ggcttgagcc ggacggcaac tgcccgctgc tggtggcggt gtagtaacgc atttcatgcg
     6661 ttgattcatt cacatagcga tagcccacgc ccacttcgtg cgcggaaggg ccgatcataa
     6721 agatctggct gtagcgtggc tcaataccgc gcacccagta gttacgcggc gagagggtga
     6781 tgcgtttgcc ttgctccagg tagccgctgc gcagggtttg ggtgtagaac ccctgaatgt
     6841 tgaatttatg ctggctgtct ggctggaact ggtagcccag gctcgccagc ttgcgacgac
     6901 cccagaagcg gtcatacggg cgggtggatt gccagcgatc ggcgtcgtaa tccgcgcgag
     6961 acaggccacc gggcatgtcg gcttcaccgt cgtaatattg cagcaggctg ttgaaggtgt
     7021 gcacctcatc cggcgcatat ttgcttttca gcatcaggtc gtcgatgcgg gtggcgctgt
     7081 gctcgcgcca gtcactgccg cgcgtgccgg agtagagcag cgcggtgcca aaaccgttgt
     7141 ccgctgtgcc gcccaccatc aggttgtgcg tctctttcgg gttgttttgt gaagaggttg
     7201 ggctgagctg accttccacg cccgcctcga taccaaagtc ctgcggaatg gcacgggtaa
     7261 caaagttcac cacgccgccc acgctctgcg gtccgtaacg caccgcacca ccaccgcgta
     7321 ccacgtcaat ggcatccatg ttgccgagcg aaacgggagc cagtgaaagc tgcggctgac
     7381 cgtaaggggc gaaggggacg gggatgccgt ccatcaggac ggtcgagcgg ctggtgaggc
     7441 gcgggttcag gccccggatg ccaaagttca tcgccaggtc gtggctgccg gtgccgttgt
     7501 tttccggcgc gctgacgcca gggatgcggt taagtacctc acgcatggtg gttgcgccgg
     7561 ttttggcgaa atcctcacgg cggatcacgt cacgcgcgcc agcatgttca aatacgtcgt
     7621 tttcacgcgc atcacccagc cagtcgccga ccacggtcag ggcatcttct tttggtgcgg
     7681 gcgcgggctc cagcgtccag ctattatttc ccagcggttt tacctgcagt ccgctgccgt
     7741 ccagcagttg ttgcaggccg ctctcgacgt cgtaatcgcc gtgcaggccg ttgctctgct
     7801 tgccgcgcgt caggctggcg tcaaccgaga gggtaaatcc gctgtgtgcg gcatactgat
     7861 tgagcgcttt atcgagcgat cccggtgcga tattaacctg tgcagcaaaa gcggaaaacg
     7921 agagaccggc cagcggcagc aggctcaggc gaatggcgtt aaccaaaggt gttgttttac
     7981 gaaaaacgcg taacggcgtc ataccttccc catcatcatt tttgttgtgt tcagctatga
     8041 gtcgaacgag aagggtaaaa aggacaatcg aaataagaat tattttcctt acagtggtga
     8101 aatgtttatc cagtaccgcg taatagactg aattttaacg ggaagcgttt gcgcgataac
     8161 gttcaggatc gcatcggtat ttttcagcgg gaacgtcccg ctcaggcgca gcccggcaac
     8221 ggcgggatcg cagcgcagca cgccgttgcg gtaacgggtt agcgtggcta tcacctcacc
     8281 cagtggttta tcgctgaagc tcaggatgtc cttcgtccag cttgtactct cgtcatccag
     8341 cggtttcact gcgccaaact cagaggcgct gaactgcagg ctttcaccag cgttcacgat
     8401 gcgtttttgc gcgggggcac tggcgagaag cacttccaca gcgtgctgct gaacgtcaag
     8461 ctgcgtgaaa ttatcctgct ggcggacggt aaattctgtc cctaaagcag tgagctggcc
     8521 ctgacgggtc aggatacgga aggggcgttg cagggcatct ttcgcggtag taatggcgat
     8581 ttcaccgtac cagagccgga cggtgcgctg atgcgcatca aaacgcacat ccgccgcgct
     8641 ttgggtattc agcgtgagca gggagccatc ttccagttgc tgacggctga ctgtgccttt
     8701 ggcggtgcgg taatctgccc gcagaccttc gccggtttcc gactgccaga gctgccagcc
     8761 tccgccagcg ccgagcaaca gcagtaatcc tttcatcacg tgacggcggg tgaggcgggt
     8821 atcgtgcaac gcccggctgg caacgtcgcc aggcacaccg ccaagctggt tgcgcaggtt
     8881 ttcaacctgc tgccaggccc actggttatc ctgatcctgt tcataccact gttgccagcg
     8941 cgcttcctgt tgtgggctga cgcgctcgcc gcttagcacg gcataccagt gggaagctga
     9001 acgcagcgcc tgacggcggg aatcggttaa caaaggattc ataacccata ctccagacgg
     9061 aacagcaggc agtgctcgac ggctttcgcc acgtattttt tcacggagct gatggaaaca
     9121 ccgagtttgt gcgcaatctc gctgtatgtc agaccatcca gttgcgaaag cagaaacgct
     9181 tcacgtgttt tgccgtttag cccgtccagc atgctgtcga ggagttgtag ggtctcgagt
     9241 tggctttcgc gttcctcagg tgaaggcgct cccccctccg gcataagcgc cagcatctcc
     9301 agatacgctt tttccagcgc gtttcggcga aacaggtcca ccatcacgcg tttggcgata
     9361 gtgcagagga aggagcgagg atcgcggatc gtcgagagcg tttcgctgac cattacccgc
     9421 aaaaaagtgt cctgggcaat gtcatctgca tcaaaagcag actggagttt gcgcgtcagc
     9481 cagcttttca accagccgtg atgtgtgcca taaagcgact cgaacgttaa ggaagctgtg
     9541 gtagtggcgc ggtcagacat gcggagtgca tcaaaagtta attatcacgt agtcatatta
     9601 atatgagaat ggttatcatt acaattggaa ataaaattgt ttccaataga catttttaac
     9661 atgttgtttt tctaagtgtt ataaggtagg tataaaatgg gatggagcct ctgcttctgg
     9721 catgtgtcgg tcagaatgac tcatgatgtg gtctgctatt attgacatcc tcactgccct
     9781 aaaggatggg gatttcggta atgctgccaa cttactgatt tagtgtatga tggtgatttt
     9841 aaggtgcttg cgtggcttcc atttccatca gatgtccttc ctgctccgct actgaaggcg
     9901 tggtgcgtaa cggcaaaagc actgccggac atcagcgcta tctctgctct cattgccgta
     9961 aaacatggca actacagttc acttacaccg cctctcagcc cggtacgcac cagaaaatca
    10021 ttgatatggc catgaatggc gtcggatgtc gcgccagtgc acgcattatg ggcgttggcc
    10081 tcaacatggt tttacgtcac ttaaaaaact caggccgtag tcggtaacct cgcgcataca
    10141 accgggcagt gatgtgattg tctgcgctga aatggacgaa cagtggggct acgtcggtgc
    10201 taaatcacgt cagcgctggc tgttttacgc gtatgacagg atacggagga cggttgtggc
    10261 gcacgtcttc ggtgaacgca ctctggccac actggagcgt cttctgagcc tgctgtcggc
    10321 ctttgaggtc gtggtataga tgacggatgg ctggccgctg tatgaatcac gcctgaagag
    10381 aaagctgcac gttatcagca agcgttacac tcagcgcatt gagcgacata atctgaatct
    10441 gagacaacat ctggcaaggc tgggacggaa gttactgtcg ttctcaaaat cggtggagct
    10501 gcatgacaag gtcatcgggc attatctgaa cataaaacac tatcagtaag ttggagtcat
    10561 tacctcctcc cgaactcaaa gctatcatac agataattac tggttaaccc tatatagggc
    10621 attttaaagt gtgatcttat ccagcaataa tggacacgcg gctaagtgaa ccgccccggg
    10681 tttcctggag agtgttttat ctgtgaactc aggctgccag atcatcgttt ccgatggaag
    10741 cataataagc tttttctgct tctgccggtg ggatatggcc ctgcctttcc agcaatcgtc
    10801 gattgttata ccagtccacc cacgtgagtg tggtcagctc atcatactga cacgtgcatt
    10861 acccctaccg cgataatgca accgtacaat atagggcgtt tcctaaacgc agccctcatc
    10921 actccaatcc aacaagacac agcatttttg atcacgaaga aagacaaata atttccgtaa
    10981 atgtttccgt tgttacaaat aacaacagtg ttttacattt ctttggcctc aggcccgcgc
    11041 atgttgccat tcgatgtcat tttcctgact cgtttcttct ttatggtgta gtgtgatctt
    11101 cactttatgg atgctaacaa tatgaaaaga aaaattattc ccgtgctaat cggttgtacg
    11161 ctctctttct ctgccctggc ggcacaacct acggctgagc gctatgtcgt cagttttcca
    11221 gaaggcacgc acgtgaacta cgccggcgca tttgccagtg cattcccgaa cggccttccg
    11281 gttgggatag gttctggcct gctgttcacc ggtaaacagg gcgatgccct gacattcgca
    11341 accattaccg atcgcggtcc gaacgcggat tcaccgaaag aggggaaaaa cgaaactaaa
    11401 attttcgtta cgccagattt cgcgccgctg ctgatgacga ttcgtgtaca aaacggcaaa
    11461 gcggaggcca tcgatccccg tcctctgcat gacgataaag gcgcgatcaa cggtctgccg
    11521 ctggcaagcg acgtgattgg ctccaccaat gaagtggcct tcagcgacac gttacataga
    11581 ctgaaggggg ataatcgcgg gctggatacg gaagggatca ctccggatgg taaaggaggt
    11641 tactggctgt gcgatgagta tggcccgttc ctgattaaca tcgacagtaa agggaaaatc
    11701 ctggcaatcc acggtccgca ggcggcggaa ggggaaaaag cgattgcggg cggtttgcca
    11761 aatatcctca aatggcgtca ggcgaaccgc ggctttgaag gcctcacccg tatgccggac
    11821 gggcgtatta ttgtcgccgt gcaaagtacg ctggatatcg acgctaagag caagaaaaag
    11881 gcgctgttta cgcgtctggt gagcttcgat ccggcaagcg gaaaaaccgc gatgtacggt
    11941 tatcctatcg acagcgcggc ctacagcaaa aacagcgacg ctaaaatcgg agacatcgtg
    12001 gcgctcgata accagcacat cctgctgatc gaacagggaa gagataaaaa caacagaatg
    12061 cgtaacctga tttacgaggt cgatctcaat aaggcgagcg acctgtcagg cttcgacaag
    12121 ccgggtgagt atccggagtt tgatgatgag aaaaccctgt cacagcgcgg cattaccctt
    12181 gcgcagaaaa cgcaggttgt tgatctgcgc tccttgggct ggcagcagga gaaggctgaa
    12241 gggttggcgc tgatcgacag caaaacgctg gcggtggcga acgataacga ctttggcgtg
    12301 aaggtggcga tgcaacatcc ggtcgagggc aagacattca aggattatcg ggtgaacgcg
    12361 gaaggaaagc tgacgcttga cgacaagcag gttgaaacga ccctcagagt gaagccactg
    12421 gagaaaccgg agtctgacag tgaactgtgg attgtgacgc tgccggaagc gttgaaataa
    12481 gtttataagg tacggacagc agtatcgctt agtttttcaa attcatgtat gtgaacaata
    12541 ttggggttcc ggcgtagacc cccaatgaaa gcgtcaccac gtgaaaacat gcctgcacgg
    12601 tttacacgtc atctcatggt ggcagccggt taactttcct gctacaccag tggaaaaagg
    12661 ccataagcag tccgaacaaa agtaagcgta cagcgagggc cgtattgacg gggatgtgtt
    12721 attcagctgg cagtgctatg cgccacggaa gcagttcgct gacccggttg accggccagt
    12781 ctgctatgac gccaggcaca tggcgaaggt agctttctgg atccacgtca ttcagtttgc
    12841 acgtcccgat caggctgtac agtagcgctc cccgctcacc accatggcca gagccgaaga
    12901 acagggtctt catcttttca cgcaaccagc tttccaggga tttcaacagc ggtttcgttt
    12961 ttcgctgacg ttcagcaagc cgctgctctg ccggcattcc ccttatatcc gcctctatgg
    13021 cgtacaactg accgatctgc tctagggctt cttccgtcag tgctgacggg atgcggacgt
    13081 gcacatcgtg gatctttcgg cgggcatgag cccagcaggc agcttccgtt atcccaccat
    13141 tgcgatacag ctcgttgaac ccggcgtacg catccgcttg cagcacaccg ctgaagcaag
    13201 caagatgagt ctgcggatgg atgccttttc tgtccgggct gtaagcgaac cacactgcag
    13261 gtgccaacgc tgacccggca ttgcggtcat cacgaacata cgcccacaac cgcccggtct
    13321 tcgtcttctt attacccggc agcagtacct ggaccggggt atcatcggca tggagtttgc
    13381 cgtcagtcat gacatagcca tgaagcgcct cttccagcgg agacagcagc cggcagcatg
    13441 catccaccca gcccgacagc agtgaacggc tcagctccac accttgccgg ccgtatattt
    13501 ctgactggca atacagcggg gtgtgctctg catacttcga ggtcagcacg cgggccagca
    13561 gccccggtcc ggcgataccc cgctcgatgg gccgcgaagg tgcaggtgcc tgcacgatgg
    13621 catcgcactg agtacaggca tgtttttccc gtaccgtccg gataacccgg aaggcgctac
    13681 gcatcaactc cag
//
LOCUS       DAFGPF010000126        13678 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFGPF010000126 DAFGPF010000000
VERSION     DAFGPF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13678
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.126"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..204
                     /locus_tag="LSX49_004214"
     CDS             <1..204
                     /locus_tag="LSX49_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417930.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170539.1"
                     /translation="GAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAI
                     ALLLTWRLKKRPPVEIPEAASSS"
     gene            complement(208..765)
                     /gene="dcrB"
                     /locus_tag="LSX49_004215"
     CDS             complement(208..765)
                     /gene="dcrB"
                     /locus_tag="LSX49_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HBL7170540.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADNQQKAQTTAENIINTLVIQ"
     gene            complement(838..1503)
                     /locus_tag="LSX49_004216"
     CDS             complement(838..1503)
                     /locus_tag="LSX49_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HBL7170541.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSIFGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRHWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            1713..1958
                     /gene="tusA"
                     /locus_tag="LSX49_004217"
     CDS             1713..1958
                     /gene="tusA"
                     /locus_tag="LSX49_004217"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HBL7170542.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            complement(2060..4258)
                     /gene="zntA"
                     /locus_tag="LSX49_004218"
     CDS             complement(2060..4258)
                     /gene="zntA"
                     /locus_tag="LSX49_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HBL7170543.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTTVQNTNDCCCDGACSSTPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     AVQKAGYSLRDEQASDEPQESRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSVAATGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLSNGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAQSQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGVIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTELNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGVFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRK"
     gene            complement(4332..4958)
                     /locus_tag="LSX49_004219"
     CDS             complement(4332..4958)
                     /locus_tag="LSX49_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HBL7170544.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            5099..5458
                     /locus_tag="LSX49_004220"
     CDS             5099..5458
                     /locus_tag="LSX49_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HBL7170545.1"
                     /translation="MSKPPLFFIVIIGLIIVAASFRFMQQRREKADNDMAPLQQKLVV
                     VSNKREKPINDRRSRQQEVTPAGTSMRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            complement(5461..5730)
                     /locus_tag="LSX49_004221"
     CDS             complement(5461..5730)
                     /locus_tag="LSX49_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HBL7170546.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLVWQKKFKVKK"
     gene            complement(5720..6316)
                     /gene="rsmD"
                     /locus_tag="LSX49_004222"
     CDS             complement(5720..6316)
                     /gene="rsmD"
                     /locus_tag="LSX49_004222"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HBL7170547.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     EKGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD"
     gene            6466..7962
                     /gene="ftsY"
                     /locus_tag="LSX49_004223"
     CDS             6466..7962
                     /gene="ftsY"
                     /locus_tag="LSX49_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBL7170548.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQEQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETP
                     EPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQAL
                     AAEVAEEAVMVVSPAEEDQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISL
                     FRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEM
                     GEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFR
                     AAAVEQLQVWGLRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKS
                     HLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLD
                     GTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            7965..8633
                     /gene="ftsE"
                     /locus_tag="LSX49_004224"
     CDS             7965..8633
                     /gene="ftsE"
                     /locus_tag="LSX49_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBL7170549.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            8626..9684
                     /gene="ftsX"
                     /locus_tag="LSX49_004225"
     CDS             8626..9684
                     /gene="ftsX"
                     /locus_tag="LSX49_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HBL7170550.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYASHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            9929..10783
                     /gene="rpoH"
                     /locus_tag="LSX49_004226"
     CDS             9929..10783
                     /gene="rpoH"
                     /locus_tag="LSX49_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HBL7170551.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            11054..12157
                     /gene="livJ"
                     /locus_tag="LSX49_004227"
     CDS             11054..12157
                     /gene="livJ"
                     /locus_tag="LSX49_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
                     /protein_id="HBL7170552.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLSWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            12306..12572
                     /locus_tag="LSX49_004228"
     CDS             12306..12572
                     /locus_tag="LSX49_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBL7170553.1"
                     /translation="MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRA
                     AEVIEQHRRMILTEESWTRVMDALSNPPSPGEKLKRAAKRLQGM"
     gene            12579..13106
                     /locus_tag="LSX49_004229"
     CDS             12579..13106
                     /locus_tag="LSX49_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL7170554.1"
                     /translation="MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKIL
                     RAYILCRNTPERQVLGYYTLSGSCFERAALPSKSKQKKIPYKNIPSVTLGRLAIDRSL
                     QGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
                     FFPTKSIELLFTPDD"
     gene            complement(13103..13486)
                     /gene="panM"
                     /locus_tag="LSX49_004230"
     CDS             complement(13103..13486)
                     /gene="panM"
                     /locus_tag="LSX49_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HBL7170555.1"
                     /translation="MKLTIIRLENFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADAGV
                     EDRGVMTAFMRALGFTAQQGGWEKR"
BASE COUNT         3408 a         3488 c         3689 g         3093 t
ORIGIN      
        1 ggggcggcgc tggcaactta caccgtattt atggatttat cgcttggcgt gaccggacca
       61 ctggctgggc tggtgatgag ttgggcgggc gttccggtaa tttatctggc ggcggcggga
      121 ctggtcgcaa tcgcgttatt actgacgtgg cgattaaaaa aacggccccc ggtggaaata
      181 cctgaggccg cctcatcatc ttaaaactta ctgaataacc agcgtattaa tgatgttttc
      241 tgcggtggtc tgtgcttttt gctgattgtc agcgggcagc gtaatttgca tggttagcag
      301 ttgattaccc acgttaccca gaataacgga agagtacgcc gtctggcctt tcgcggagat
      361 aatgctgtct aactgctgca ttttgtgacc tttcagctca atggctttat tggttaccac
      421 ttgcagctgc ggatcgcggc tacgttgctg atcttccaga cgcttcgcca gcaccgccag
      481 atcttctttc ggatcatcgc ccatgatgac gatgactgct ttctgcccgg tggcgtcgga
      541 ccagacatgc atgttattgg cctgcgttcc cagcttaccg ctctggtcgg tcatatccgc
      601 tggcagcgag aaacttaact tgccatcaag caggttgacg ggattcccgg tcgcgttact
      661 ttctgcgacc gaaccctgcg ccgtagcgtt agtgtcttta tcatcacagg ccgcaagccc
      721 cataaccagc aggccaattc cgacatattt aaccagattg cgcattgact tcttcctttc
      781 gataaacggc cataacggct cattcatcca tcttatcaca actctgataa cgaaccttta
      841 actcgcctgc aaagcgttga tttcggattt atctgccagt cttttcaaca gcatattgag
      901 taatacgcca tacattggca ggaagaaaac gatactgatt aacactttga aacagtaatc
      961 gaccagcgcg atttccatcc agtgttcagc cataaaggca tccgggctac gccagaaggc
     1021 aatgaagaag aaggccagcg tgtcgctgac gttaccgaac agtgtggacg ctgtcggtgc
     1081 cagccaccag tgacgactct gacgcaggcg gttaaaaacg tgcacgtcga ggatctgccc
     1141 cagcgcgtag gccatgaaac tggcggtggc gatacgggcg acaaacaggt tgaagtgggc
     1201 gagcgcgccg aatccttgcc atgaccccat ataaaacagc gatgagatga cgtaggagat
     1261 cagcaatgcg gggatcatta ccgcaaagat gatgcgacga gccagcggcg cgccaaaaat
     1321 acgcacggtc aggtcagtag cgagaaagat aaacggaaag ctaaacgcgc cccaggtggt
     1381 atgaaaacca aaaatggaga ccggaagctg aaccagatag ttactggagg tgatcaccag
     1441 aagatgaaat aacgataacc agaacaacgc cttatagcgt tgcgtttgcg agaaaacgtt
     1501 catattgtac ctttttgatt aaccattggg gtgagggaac ccaatacgtg cgacacgcta
     1561 ttttatacgt gctgaccctt ttttcgagcc gccgcatgat actgctttac gttgacaatg
     1621 caatggttaa ttttcacgca atcgttaacc tggtttgctt acggactcac agggcgtaaa
     1681 ctagcgccgt ttttttatgt gatgagaaga aaatgaccga tctcttttcc agccctgacc
     1741 acacactcga cgcacttggc ctgcgctgcc cggaaccagt aatgatggtg cgcaaaacag
     1801 tgcgcaatat gcagccaggt gaaacgttgc tgattattgc tgacgatccg gcgacgaccc
     1861 gcgatattcc tgggttttgt acctttatgg aacacgaact ggttgctaaa gagacggatg
     1921 gactgcctta tcgttatttg attcgtaaag gcggttgatg ggggaagatt ggcttcgatg
     1981 ccgccttttc ccctcaccct aaccctctcc ccagaggagc gaggggaccg atcgcgctca
     2041 atgttgcgat cggtttgcct tatttcctgc gcaacagcct taacgcattc gccgttacca
     2101 gcaccgtcgc accggtatct gccagcactg ccagccacag tccggtcatc cctaacagcg
     2161 tcgtgacgag gaaaacgcct ttcagcccca gcgcaatagt gatgttctgg cggatattgg
     2221 cgtgagtggc gcgtgccagt tcaatcattt gcaccagacc gcgcaggtgg ttatgggtta
     2281 atgctgcatc ggcggtttcc agcgccacgt ctgtgccgct acccattgca atcccgatgg
     2341 cggcagcttt catcgctggc gcgtcgttaa taccatcacc gaccatcgcc agcggcgcat
     2401 gttgattcag ctcggtcacc gctttgactt tatcttccgg caagaggccc gctttaaatt
     2461 ccagccccag ttccccggcg attgccgctg ctgcgcgtgg attatcgcct gtaaggatca
     2521 cccctttgac gcccagcgcg ttcagttcac tgatagcagt tgcagcatcg gcgcgcaggg
     2581 tatcctgcaa cgcaatgaca cccagcacgt catcgttacg tactaccagc actaccgttt
     2641 gcccggcgct ttccagttca ttaatcaaac cagcaaatgc atcagcagga tgttttccgg
     2701 cagcgcatat caacacgcgc tcaccgttaa cctgcgcttc aatgccagac ccgaccagcg
     2761 cccgctgtga ttgggcggta ggaatggcga gttcagcaac ctgtgcttcg cgcacaatgg
     2821 cctgtgccag tggatgcgtc gcgccttgct cgaccgccgc cgccagtgtc agcagttcag
     2881 attcactaat acccgttgcc ggatgaatcg cggtaacgcg cggtttaccg acggtcagcg
     2941 taccggtttt atcaaacgcc acctgggtaa cacgacccag ctgctccagc gccgcgccgc
     3001 ctttaatcaa cgccccacga cgcgctgctg ccgccagccc ggaggtaatc gccgcgggcg
     3061 tggagataac taaagcacac gggcaaccaa tcagcagcag cgtcagccct ttataaatcc
     3121 actcctgcca gctggcggca aacagcagcg gcggcaccag cgttaccagc agggcgaccg
     3181 ccataatcgc tggcgtgtaa atacggctga aacggtcgat aaaccgctca ataggtgcgc
     3241 ggcgctcttc ggcttcttca atcagtttca gaatccggtc aatggcgctg gcacccggtt
     3301 ctgacagcac ttccagcgtt accagacggt ctacgctggt ggcgcctgca ggaactttat
     3361 cgcccgtcgc gcgctccacc ggaatggatt cgccggtcag ggcactttca tcaaaactgg
     3421 caaacggtga gagcagttta ccgtcggcag gcaaacgccc acctgccgca acttcaatca
     3481 catcgccagg ccgcaggctg tttattgcca cctcttcacg ctcaccgtta ctcagacgcg
     3541 tggcggtttc tggcttcagc gccattaacg cgctgacccc ttgacgcgcg cgactggcgg
     3601 cccagccttc cagtcgttca ccaatcaaaa acagcagcaa caccatcgca gcttcagccg
     3661 ttgcgccaat aaacagcgcc ccagtagcgg ctacgctcat taaggtttca atggcgaagt
     3721 agctgccaga tttgatcagc cgtaatgcct gacgagcaat tgggtacagc ccaaccagcg
     3781 tggtcgcgat aaacgccagt tgaccaaacg gatgattgaa ctgctccagc ccccaactga
     3841 ttgccatcat cacgataagc gtaatcagcg gcagattctc tttcaggcgt gattcttgtg
     3901 gttcgtcgga ggcctgttca tcgcgcaggg aatagcccgc tttttgcacc gcagattcaa
     3961 cttgtgcccg gatgtcattg tcggcatcca ccaccagttt ttcggtggcg aacaacacct
     4021 gtacctgatt cacgcctgca agctggcgca cggcattttc cactttgcgc gcacaggcgg
     4081 cgcagtccat accgctgact ttccagctat agcgggtgcc ggagacgttt tcagagagag
     4141 ttggcgtgct ggaacatgcg ccgtcgcagc aacagtcgtt ggtgttctgt accgtagtta
     4201 gcggtttgaa cgcagcaaat tgaggggctt tcttgccgtg attgtcagga gtcgacatgg
     4261 catcctccgg ttaagttttt tctcattaac cgaaggatac actctggagt cgactccaga
     4321 gtcaagtttt atcagagata cagcgagcgg acgatgagga agtgaccagc aaagtagcag
     4381 gccgcagcaa tcgcgttatc cgcacggaag cgtcggcgat agtgactacc cagccagaca
     4441 aagttactga taaacagcaa cgaagcgcca acaaacgcag agagcgccgg agcggtcgga
     4501 cggaagaacc acagttcacc tgccagccac accatcacca gcgtcatgcc gataaacgtg
     4561 cagataggcc aacggtactc ttccaggcgc gtccagataa tcgccagtaa cagcgcgccc
     4621 agaaccagca gcaccagtgg cagaggccag aagaaagaga gcgtcatctg actggcgaaa
     4681 tagatggtgt acagcaggtg cgagaggaaa aacgcgccga tggcgtacat cagacgttga
     4741 cgtggcaaca gggttagcgc atcgcccagc agtgaggcac acagccccgc cagcaccaga
     4801 tagctaatgg cgtcgaacat cggcgcttgc caggccagca acagcaggag aagaagggtt
     4861 aacggtttaa acacccagcg ttgccaggtt ggcccacgat acgatgcatc cacagatagc
     4921 catgcggaaa gacagacagc gataaacgac caaagcatct tagttccttg aattcgttat
     4981 tttttcgtaa gcggaatgcc tacggtcttg cttccagttt agtggcgagg gtggacggat
     5041 gacaacacca taactggcag ggtatgctta tttccgcatt ttccgatgag ggataaagat
     5101 gagtaaacca cctcttttct ttattgttat cattggctta atcatcgtcg ccgcatcgtt
     5161 tcgttttatg caacaacgac gggaaaaagc tgataatgat atggcaccgc tccagcaaaa
     5221 gctggtggtg gtgagcaaca agcgggaaaa accgattaac gatcgccgtt cgcgccagca
     5281 ggaagtgacg ccggcaggca ccagtatgcg ctatgaggca agcttcaaac cgcaaagcgg
     5341 aggaatggag cagacgtttc gcctcgacgc ccagcagtac cacgccctga cagtgggcga
     5401 taaaggtacg ctgagctata aaggaacgcg ctttgtcagc tttgtaggcg aacaataagg
     5461 ttatttttta actttaaatt tcttctgcca gaccagcagt tcaaacacgc cgaaaaggaa
     5521 aatccgcacc ttttcggcgg tggtcatctg cgggccatct ttcggtaaag tggatttcaa
     5581 tagcgccagc tgcataccat gcatcagcac ggtaaaaatc agcgccacgt taacgaaaat
     5641 attcagcggg cgtgggaagg gatgcaccag gttgaggatt aaaaatcccc aaacacagag
     5701 cattaacaaa cgaccaatat taatcagcat cactttctcc ttgtgcttcg cgttgataca
     5761 gccgataagc cacctgaccc gccacttttt cccgatgtaa tgaccagttt gccggaacag
     5821 tgggcagacc cttttcgact tcgctttcga cataaatcag ggcttcgtca gccagccagc
     5881 cgttatcttc cagtaaattt atcgtctctt ctaacaagcc acggcggaac ggtggatcga
     5941 caaacacgat attatgcggt gtgccttttt gcgccaggaa tgacatcgcg ttgctgttca
     6001 ccacgcgtgc attgcctgct tttagtgtcg ccagattctt aattaactgc tgagaaaccg
     6061 cacgatccat ctcaatcaac gtggcccccg cagcgtagcg cgataacgct tccagcccca
     6121 gcgcgccgct cccggcgaag caatccagac attgggcgtc aacaatgacc ggagccagcc
     6181 agttaaacaa cgtttcgcgt acgcggtcgg tggtggggcg cagacctgga ctatcaggaa
     6241 ccgggagttt acggcctcgc cactgcccgc caataatgcg gatttggccg ctgccggaat
     6301 gattcggttt tttcatgata aattgctcaa tccgccagat aacacatact tgcaggcggt
     6361 gatgtgaatt aagttaagtg atagactatt tcatcatttt tttagctgct atgtacatag
     6421 cgttaacgct gtgccatgaa gcaacagcga ggagtgtagt cgcaaatggc gaaagaaaaa
     6481 aaacgtggct ttttttcctg gctgggcttt ggtcaaaaag agcagacccc ggaaaaagag
     6541 acagaagttc agaatgaaca accagttgta gaagaaatcg ttcaggagca agagcctgtg
     6601 aaggcttctg aacaagccgt tgaagagcag ccgcaggcgc atactgaagc cgaggcggaa
     6661 acttttgctg ccgacgttgt ggaagttact gaacaggttg ctgaaagtga aaaagcgcag
     6721 cctgaagcgg aagtcgttgc acagccggaa ccggtcgtag aagaaacgcc ggagccagtg
     6781 gctatcgaac gtgaagaact gccgttgccg gaagacgtca acgccgaagc ggtttcgcca
     6841 gaagagtggc aggccgaagc ggaaaccgta gagattgtcg aagcggcgga agaagaagcg
     6901 gctaaagaag aaatcaccga cgaagagccg gaggcacagg cgctggctgc cgaagtggca
     6961 gaagaggcgg taatggtggt ttctccggca gaagaagatc agccggtgga agaaatcgct
     7021 caggagcagg aaaaaccgac caaagaaggt ttcttcgcgc gcctgaaacg cagcctgtta
     7081 aaaaccaaag aaaatctcgg ttccggattt atcagcctgt tccgcggtaa aaaaatcgac
     7141 gatgatctgt ttgaagagct ggaagaacag ctgttgatcg ccgatgtggg cgtggaaacc
     7201 actcgtaaaa ttatcaccaa tctgacagaa ggcgcatccc gcaagcagct tcgtgatgcc
     7261 gaggcgctct atggcctgct gaaagaagag atgggcgaga ttctggcgaa agtcgatgag
     7321 ccgctgaatg ttgaaggtaa aacgccgttc gtgatcctga tggtgggcgt caacggtgtg
     7381 ggtaaaacca cgacgattgg taagctggcg cgtcagtttg agcagcaggg taaatcggtg
     7441 atgctggcgg caggcgatac tttccgtgcg gcagcggttg aacagcttca ggtctggggt
     7501 ctgcgcaaca atattccggt gattgcccag cataccggtg cggattccgc ttctgttatc
     7561 ttcgatgcca ttcaggccgc taaagcgcgt aacatcgacg tcctgattgc cgataccgcc
     7621 ggacgcctgc aaaacaaatc gcacctgatg gaagagttga agaaaatcgt ccgcgtgatg
     7681 aagaaactcg acgttgaagc tccgcatgaa gttatgctga ccatcgatgc cagcaccggg
     7741 cagaatgcgg taagccaggc caaactgttc cacgaagccg ttggcttaac cggcatcacg
     7801 ctaacgaaac tggacggcac ggcgaaaggc ggggtaattt tctcggtggc tgaccagttt
     7861 ggtatcccta tccgctacat tggtgtcggc gaacgtattg aggatttgcg tccgtttaag
     7921 gcggacgact ttatagaggc actttttgcc cgagaggatt aacaatgatt cgctttgaac
     7981 atgtcagcaa ggcttatctc ggtgggagac aggcgctgca gggcgttacg ttccatatgc
     8041 agccgggtga gatggcgttt ctgaccggtc attccggcgc agggaaaagt accctcctga
     8101 agctgatctg tgggattgag cggcccagcg ccgggaaaat ctggtttagc ggccatgaca
     8161 tcacgcgtct gaaaaaccgt gaagttccgt ttctgcgccg ccagattggc atgattttcc
     8221 aggatcacca tctactgatg gaccgtactg tctatgataa cgtggcgatc ccgctgatta
     8281 tcgccggtgc cagcggtgat gacattcgtc gccgggtgtc ggcggcgctg gataaagtcg
     8341 ggctactgga caaagcgaag aacttcccta ttcagctttc cggcggtgaa caacagcgtg
     8401 ttggcattgc ccgcgcggtg gtgaacaagc ccgcggtact gctggcggac gaaccgactg
     8461 gtaacctgga cgacgcgctg tcggaaggca ttttacgtct gtttgaagag tttaaccgcg
     8521 ttggagtaac cgtattgatg gcaacgcacg acatcaacct gatttcgcga cgttcctatc
     8581 gcatgctcac cctgagcgat ggtcacttgc atggaggcgt gggccatgaa taagcgcgat
     8641 gcaatcaatc acattcggca gtttggcggg cgtctggatc gcttccgtaa atcggtcggc
     8701 ggctctggcg acggcggtcg taacgcgccg aaacgcgcga aatcctcgcc aaaaccggta
     8761 aatcgcaaaa ccaacgtttt caacgaacag gtacgctatg cctcccacgg cgcattgcag
     8821 gatctgaaaa gcaaaccgtt cgccacgttt ttaacggtga tggttatcgc catctccctg
     8881 acgctgccca gcgtctgtta tatggtgtac aaaaacgtta accaggcggc gacgcaatat
     8941 tatccgtcac cgcaaatcac tgtttatctg caaaaaacgc tggatgatga cgccgctgcg
     9001 ggcgtggtgg cacagttgca ggccgagcaa ggcgtggaga aagtgaatta tctttctcgt
     9061 gaagacgcac tgggcgagtt ccgtaactgg tctggttttg gtggtgcgct ggatatgctg
     9121 gaagaaaacc cgcttccggc agtggcggtg gtgatcccga aactcgattt tcaggggacg
     9181 gagtcactga atacgctgcg tgatcgtatc acgcagatta acggcattga cgaagtgcgg
     9241 atggatgaca gctggtttgc ccgcctggcg gcgttgaccg ggctggtcgg gcgcgtttcg
     9301 gcaatgatcg gcgtattgat ggtggcggca gtattcctcg tcatcggtaa cagtgtgcgc
     9361 ctgagtatct ttgctcgccg tgattctatt aacgtgcaga aactgattgg tgcgacggat
     9421 ggtttcatcc tgcgtccgtt cctgtacggt ggcgcattgc tgggattttc tggcgcattg
     9481 ttgtcactaa ttttgtcaga aattctggtg ctgcgtttgt catcggcggt tgcggaagtg
     9541 gcacaggttt tcggaacgaa gtttgatatc aatggcttat cgttcgatga atgcctgcta
     9601 ttgctgctgg tatgctcgat gattggctgg gtggcagcgt ggcttgccac ggtacaacat
     9661 ttacgccact ttacgcctga ataataaaag cgtgttatac tctttccctg caatggattc
     9721 cgtagcaggg aaagagaccc cgttgtctct tcccggtatt ttatctctat gtcacatttt
     9781 gtgcgtaatt tattcacaaa cttgcattga acttgtggat aaaatcacgg tctgataaaa
     9841 cagtgaatga taacctcgtt gctcttaagc tctggcacag ttgttgctac cactgaagcg
     9901 ccagaagata tcgattgaga ggatttgaat gactgacaaa atgcaaagtt tagctttagc
     9961 cccagttggc aacctggatt cctacatccg ggcagctaac gcgtggccga tgttgtcggc
    10021 tgacgaggag cgggcgctgg ctgaaaagct gcattaccat ggcgatctgg aagcagctaa
    10081 aacgctgatc ctgtctcacc tgcggtttgt tgttcatatt gctcgtaatt atgcgggcta
    10141 tggcctgcca caggcggatt tgattcagga aggtaacatc ggcctgatga aagcagtgcg
    10201 ccgttttaac ccggaagtgg gtgtgcgcct ggtctccttc gccgttcact ggatcaaagc
    10261 agagatccac gaatacgttc tgcgtaactg gcgtatcgtc aaagttgcga ccaccaaagc
    10321 gcaacgcaaa ctgttcttca acctgcgtaa aaccaagcag cgtctgggct ggtttaacca
    10381 ggatgaagtc gagatggtgg cccgtgaact gggcgtaacc agcaaagacg tacgtgagat
    10441 ggaatcacgt atggcggcac aggacatgac ctttgacctg tcttccgacg acgattccga
    10501 cagccagccg atggctccgg tgctctatct gcaggataaa tcatctaact ttgccgacgg
    10561 catcgaagat gataactggg aagagcaggc ggcaaaccgt ctgaccgacg cgatgcaagg
    10621 tctggacgag cgtagccagg atatcatccg cgcgcgctgg ctggacgaag acaacaagtc
    10681 cacgttgcag gaactggctg accgttacgg tgtttccgct gagcgtgtgc gtcagctgga
    10741 aaagaacgcg atgaaaaaat tgcgcgctgc tattgaagcg taatttccgc tattaagcag
    10801 agaaccctgg atgagagtcc ggggtttttg ttttttgggc ctctacaata atcaattccc
    10861 cctccggcaa aacgccaatc cccacgcaga ttgttaataa actgtcaaaa tagctattcc
    10921 aatatcataa aaatggggta tgttttagca gagtatgctg ctaaagcacg ggtagctacg
    10981 tataaaacga aataaagtgc tgcacaacaa catcacaaca cacgtaataa ccagaagagt
    11041 ggggattctc aggatgaaca taaagggtaa agcgttactg gcaggatgta tcgcgctggc
    11101 attcagcaat atggctctgg cagaagatat taaagtcgcc gtcgtaggcg caatgtccgg
    11161 tccggtggcg cagtacggtg accaggagtt tactggcgca gagcaggcgg ttgcggatat
    11221 caatgctaaa gggggtatca aaggcaacaa actgcaaatc gtaaaatatg acgatgcctg
    11281 tgacccgaaa caggcggttg cggtggcgaa caaagtcgtt aacgacggca ttaaatacgt
    11341 gattggtcac ctctgctctt catcaacgca gccagcgtct gacatctacg aagacgaagg
    11401 cattttaatg atcaccccag cggcaaccgc accagagctg accgcccgtg gctatcagct
    11461 gatcctgcgc accaccggcc tggactccga ccaggggccg acggcggcga aatatattct
    11521 tgagaaagtg aaaccgcaac gcattgctat cgttcacgac aaacagcagt acggcgaagg
    11581 tctggcgcgt gcagtgcagg acggcctgaa gaaaggcaat gctaacgtgg tgttctttga
    11641 tggcatcacc gccggggaaa aagatttctc taccctggtg gcgcgtttga agaaagagaa
    11701 tatcgatttc gtttactacg gcggttatca cccggaaatg gggcaaatcc tgcgtcaggc
    11761 acgcgcggca gggctgaaaa ctcagtttat ggggccagaa ggcgtggcta acgtctcgct
    11821 gtctaacatt gcgggcgaat cagcggaagg gctgctggtg accaagccga agaactacga
    11881 tcaggttccg gcgaacaaac cgattgttga cgcgatcaaa gcgaaaaaac aggacccaag
    11941 cggcgcgttc gtctggacca cctacgccgc gctgcaatct ttgcaagcgg ggctgaatca
    12001 gtctgacgat ccggcggaga tcgctaaata cctgaaagcg aactcggttg atacggtgat
    12061 ggggccgctt agctgggatg agaaaggcga tctgaaaggc tttgagttcg gtgtgtttga
    12121 ctggcacgcc aacggcacgg cgactgatgc gaagtaacag atagataaat gaaaataccc
    12181 gatgcgctga actgccatcg ggttttttta tatttatcga aatggttgta gaaagattga
    12241 acaattcagg atatgcttat gtacggtgat atgccgtaca tattatacgg agcaggagag
    12301 ttcacatgtc tgctgttaaa aagcagcgta ttgatctgcg tttaactgac gatgacaaaa
    12361 gtatgattga ggaagcggca gcgatatcta atcagtccgt cagccaattt atgttgaaca
    12421 gcgcttcgca gcgagctgcg gaagtgattg aacagcatcg gcggatgatt ctcactgagg
    12481 aatcctggac gcgggtgatg gatgcgctga gtaatccacc gtcaccaggt gaaaagctaa
    12541 aacgtgcggc aaaacgtctt cagggaatgt aatactttat ggatgatctg acgatagaga
    12601 ttctgaccga tgatgcagat tatgatctac agcgattcga ctgcggcgag gaagcattaa
    12661 atctctttct gacgacacat ctggttcgtc aacatcgcaa taaaattctg cgagcgtata
    12721 tcctgtgtcg caacactcca gaacgtcagg tgctgggata ttacacatta tccggcagtt
    12781 gttttgaacg agccgcactg ccctcgaaat cgaaacagaa aaaaattccc tacaaaaata
    12841 ttcccagcgt aactcttggg cgtctggcaa ttgatcgttc attacagggg cagggatggg
    12901 gagcaacact ggttgctcat gccatgaaag ttgtctggtc agcctcttta gcggtaggta
    12961 ttcacggtct ttttgtcgag gcgctgaatg aaaaagccca tacgttttat cagtcgctgg
    13021 gctttatccc attggtcgga gaaaacgaaa atgcgttatt tttcccgacc aaatctatag
    13081 agctactttt tacaccagac gattaacgct tctcccagcc accctgttgt gccgtaaatc
    13141 ccagtgctcg cataaacgcc gtcatcacgc cgcgatcttc cacgccagca tccgccatcc
    13201 accaacatga aacgccagga ttgttacgca aaacctcttc cagcagatat tgccccacac
    13261 cgcgacgtcg ggttacttcc cgcacgcgta gagaatccag tgccccctcg gtgccgctta
    13321 aggttacccg cacggcagcg agcaggcgct cgttaaaacg cgcggcgtag atgcggtggt
    13381 tatcgtcaac ctgtaaagag gaaggggaat actccggcca gatcttttgc aggtcaatcc
    13441 ggtcctggtc gctaaagttt tctaatcgaa tgatggtcag cttcatgggg aacccgtgta
    13501 aatcacaaaa gtggaaccag tgtagcgaaa taatttaatc ggaggctttc tcttttttat
    13561 ttcttttggc aggtgattaa ttttttttca gcaataatta caaagttaaa acattagaga
    13621 atgaaaaata tccagcataa tcccctaaat ggtagtgaat tattctgccc tttgtacc
//
LOCUS       DAFGPF010000127        13667 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFGPF010000127 DAFGPF010000000
VERSION     DAFGPF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13667
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.127"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..479
                     /locus_tag="LSX49_004231"
     CDS             <1..479
                     /locus_tag="LSX49_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL7170556.1"
                     /translation="IEEHISGSVAASERPGFIRLLDRMENGDVLIVTKLDRLGRNAMD
                     IRKTVEQLAALDIRVHCLALGGVDLTSPAGKMTMQVISAVAEFERDLLLERTYSGIAR
                     AKAAGKRFGRPPILSEEQKQTVTERLNAGISISAIAREFNTTRQTILRVKAGLLQE"
     gene            664..1221
                     /locus_tag="LSX49_004232"
     CDS             664..1221
                     /locus_tag="LSX49_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HBL7170557.1"
                     /translation="MSTTVKPSADAAAIHNTREAVRSQPGLGNLTFQMKARSSGGLTV
                     RTETGATIQNGVIDTSRVGKFSNIGDEPAGLLGTDTGMSPTEYIMQALAGCYTATLTM
                     MAAEKGIDLDGIELDLNFDINLNGFLGLDSNVRKGAKSIRVDVHLTSKTASREELEAL
                     VSEMQKNSPIHDTLANPVEMITRLA"
     gene            1363..1944
                     /locus_tag="LSX49_004233"
     CDS             1363..1944
                     /locus_tag="LSX49_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7170558.1"
                     /translation="MTTMTRERLLSEAEHLMREKGYSAFSYADLSKIVGITKASIHHH
                     FPTKDILGEQVVIQAFSDTQRVFEQIEATEKSAERRIAAYIDIFAQSHKASLLPLCCA
                     LSAETANLPQAITVQTSLYFDMQIEWLTKVVRAGMESGEFSSHAEPSDIALMIINVCE
                     GSSVVAHATARPEVFANSLKYIKLLLNTPHSGE"
     gene            1949..2287
                     /locus_tag="LSX49_004234"
     CDS             1949..2287
                     /locus_tag="LSX49_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL7170559.1"
                     /translation="MLDWNNYRSELMQRLGELGKLTPETMKGVVALGNAGNKTDLLGA
                     KVRELIALACAVTTRCDGCIAFHADAAVKAGATDAEIAEALGVAINLNAGAAVIYSAR
                     TLDAVGQARG"
     gene            complement(2317..2646)
                     /locus_tag="LSX49_004235"
     CDS             complement(2317..2646)
                     /locus_tag="LSX49_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002431133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL7170560.1"
                     /translation="MRTLTAYNEDNFRQIEQYKGISVVRFSAPWCPPCQASEEMFSQF
                     ADRLDRDIQVGKVNVDQAPVLTTKYEIWGLPSVLIFHEGQLVKRIPGVKPASVYAQAI
                     ADIKKGQ"
     gene            2860..3966
                     /locus_tag="LSX49_004236"
     CDS             2860..3966
                     /locus_tag="LSX49_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkene reductase"
                     /protein_id="HBL7170561.1"
                     /translation="MSKLFTPYNLSGLALKNRVVMAPMTRTRTMNEVPDEVVALYYAQ
                     RASAGLLITEGMPVSEEGRGYLYTPGIYNDEHVQGWRKVTQAVHAKGGRIFAQLWHVG
                     RMSHVSLQPGHIAPVSAGTVQAVNTTVFALTESGEPGPVVPSQPRALETHEVKRITAD
                     FVHSARLAMEAGFDGVEIMAANGFIFDQFLSSELNTRTDEYGGSVENRQRFLLETIDA
                     VAEAVGNSHVAVRLSPFGRIYDLAPYEGEEQTWSAITDALGQRELAYVHLYYQPVYTK
                     APLPEGFRRRFRNTFKGTIIAAGGFTRDIAEQALEDDELDLVAFGVPYIANPDLVERM
                     QNGWPLAESDRATYYGVSGSPEKGYTDYPVWQAQ"
     gene            4032..4733
                     /locus_tag="LSX49_004237"
     CDS             4032..4733
                     /locus_tag="LSX49_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family oxidoreductase"
                     /protein_id="HBL7170562.1"
                     /translation="MQTLKHTLTIDIWSDLVCPWCWIAKKRFEQGLNRFEFRDQVVIR
                     HHSYRLAGGTPAMPFKDAIVKKLGSQHSAELMMDQVGTAGKSEGLIYNFDGMMFGDTE
                     DAHTLLVAARKAGIADAVEERFYHGSITEGRSLFDRQQLVAMAVEAGMEKADAEAALE
                     NDDFRATVSDDEAHAQSIGLSGVPVFVMNEKYAISGAQGADNFLNALRQVWDEQQTEF
                     SATAGQTCGTDGCSI"
     gene            4799..5572
                     /locus_tag="LSX49_004238"
     CDS             4799..5572
                     /locus_tag="LSX49_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7170563.1"
                     /translation="MNTFFKGKKLLVVGGTSGMGLAVARMVLEAGGSVVLTGNKKDKA
                     EAVQKELGPLGPVAVIAANLMTEEGMETIRHEINASHRDISLMVNAAGIFMPKGFTEH
                     SFADYDMYFSLNRATFFITQDVVKNMLAAKLEGSIVNVGSIGAQAALGDSPSSAYSMA
                     KAGLHALTRNLAIELASAGIRVNAVSPGIVHTPIYEGFMDKADIADAMKSLNDFHPLG
                     RVGTAEDVANTILFLLSDKTSWVTGAIWDVDAGIMAVRR"
     gene            complement(5758..6981)
                     /locus_tag="LSX49_004239"
     CDS             complement(5758..6981)
                     /locus_tag="LSX49_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL7170564.1"
                     /translation="MKYDFDEYVSREKTDSLTVDGWREYLFAGQSEFAMRYPAEGLIN
                     LWVADMAFATPEPILQAIRDRLDRKILGYTKIYDEEYYEIFGNWCERQYGHRFKTEDI
                     VLSPGIIPALNRLVPLLTDKDDSILIMTPSYGPFKKAGEYSQRRVVYSALKKSAGGWE
                     PDWEDFTRKASQADLRVKILFLCNPHNPTGRVWRPDELKRIIEICLANDIWVISDEIH
                     CDLSRSGIGHTPAASLFPDSTRIITCMSSSKTFNLAGNLLANIIIPDPGVRSEWRLRH
                     DEFISPLSLAANKAAWSECDDWLVHLREYIDGNFQYLHDYLKSYLPETRFSIPEGTYL
                     AWIDISHYLPDTVGEDLSLYFARESGVLLEGGLLFVDNGEGHIRLNLACPRTMLTAGM
                     KRISQVLRTPAPNRV"
     gene            complement(7112..7984)
                     /locus_tag="LSX49_004240"
     CDS             complement(7112..7984)
                     /locus_tag="LSX49_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBL7170565.1"
                     /translation="MARCALILKISLAMLAFAANSILCRLALQGGHIDPLSFSSLRLA
                     SGAFVLSPFLFYHARTTLSLWRPLSGFYLMAYAVLFSVAYIHLDTGAGALLLFGAVQF
                     AMVIHGLFKGESLSAMRACGLVLALTGIAALLLPGTKAPPLYSALMMIVSGLAWAAYS
                     VRGRAGQAAGASTAANFILAAPMALALTLLFMKQGHSDAAGIALSLLSGAVASAGAYV
                     LWYTLLPSLGSITASILQLSVPCLAMLGGVVFLGESLTVRTIFSALAVLTGIVMVTRE
                     KSPRQPMAKARKPQ"
     gene            8226..8978
                     /locus_tag="LSX49_004241"
     CDS             8226..8978
                     /locus_tag="LSX49_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7170566.1"
                     /translation="MKKLKFTFKNAAGEELAGLLELPENPKAFALLAHCFTCGKDLKG
                     AARIARKLTEKAIAVLRFDFTGLGNSEGDFSNTNFSSNISDLLCAVDYLRRQYEAPSL
                     LIGHSLGGSAILSIAGEVPEAKAIVTIGSPGELTHVKRLFKDDVENINQHGAYPVELA
                     GRVFTLKKQMLDNIQEHKIAHKVFAMNKPLLIFHATEDDTVLIEQAEKIFKAAKHPKS
                     FISLGKADHLLTHAQDAEYVADIIISWSECYL"
     gene            9005..9318
                     /locus_tag="LSX49_004242"
                     /pseudo
     CDS             9005..9318
                     /locus_tag="LSX49_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011846847.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            complement(9336..10252)
                     /locus_tag="LSX49_004243"
                     /pseudo
     CDS             complement(9336..10252)
                     /locus_tag="LSX49_004243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019462.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            10354..10923
                     /locus_tag="LSX49_004244"
     CDS             10354..10923
                     /locus_tag="LSX49_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7170567.1"
                     /translation="MFSAISQKTGLSNVTPILGTSDNGNGTNLAIIGFNSEPDKKAVS
                     TAASFANSSYRLFSTEMNNLNKRMGDIRDSGEAGVWGRYMLGQGSGTDGYQNTYNHLQ
                     LGADKGIRIESAMLYTGLIFTHTSTNAELSGSYYGDTKSYGLGGYTSIFFDNGFYTDF
                     IAKYIHSTNVYSYLSPSEPPRVSWRVFYL"
     gene            complement(10926..11399)
                     /locus_tag="LSX49_004245"
                     /pseudo
     CDS             complement(10926..11399)
                     /locus_tag="LSX49_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(11489..12997)
                     /gene="ltrA"
                     /locus_tag="LSX49_004246"
     CDS             complement(11489..12997)
                     /gene="ltrA"
                     /locus_tag="LSX49_004246"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL7170568.1"
                     /translation="MQRKLATWAVTDPSLRIQRLLRLITQPEWLAEAARITLSSKGAH
                     TPGVDGVNKTMLQARLAVELQILRDELLSGHYQPLPARRVYIPKSNGKLRPLGIPALR
                     DRIVQRAMLMAMEPIWESDFHTLSYGFRPERSVHHAIRTVKLQLTDCGETRGRWVIEG
                     DLSSYFDTVHHRLLMKAVRRRISDARFMTLLWKTIKAGHIDVGLFRAASEGVPQGGVI
                     SPLLSNIMLNEFDQYLHERYLSGKARKDRWYWNNSIQRGRSTAVRENWQWKPAVAYCR
                     YADDFVLIVKGTKAQAEAIREECRGVLEGSLKLRLNMDKTKITHVNDGFIFLGHRIIR
                     KRSRYGEMRVVSTIPQEKARNFAASLTALLSGNYSESKVDMAEQLNRKLKGWAMFYQF
                     VDFKAKVFSYIDRVVFWKLAHWLARKYRTGIASLMRWWCKSPKPGQSKTWVLFGKTNH
                     GKLSGEILYRLVGQGKKLFRWRLPEGNPYLRTETRNTYTSRFTEVAMAFASI"
BASE COUNT         3311 a         3567 c         3525 g         3264 t
ORIGIN      
        1 ttattgagga gcatatcagt ggctcggttg ctgccagcga acgccccgga tttatccggt
       61 tgctagatcg catggaaaat ggggatgtac tgattgtcac caaacttgac cgtctgggtc
      121 gtaatgcgat ggatatccga aaaacagtag agcaactggc ggctttagat attcgcgttc
      181 attgtctcgc actcggaggc gttgatttga ccagtccggc cggaaaaatg actatgcagg
      241 taatttctgc tgtagcggag tttgagcggg atttgctgct tgagcgaacg tattcaggta
      301 ttgcgagggc aaaagcggct ggaaaacgct tcggtcgccc ccccatcctg agcgaggaac
      361 aaaagcaaac agtgacagag cgcctaaatg ctggcatcag tatcagtgct attgcccggg
      421 aatttaatac cacccgccag actatccttc gggtaaaggc tggattgctg caagagtgag
      481 cggctgggaa gattataaaa aaatcaaatg gttattatga aataaaacag ccttctgggt
      541 tcttttcccc ctatttttta taaaagagta gacaaaagag gttcgcgata ttaacctgcc
      601 aactagatgg ttggcactga ttacaccagc tataactttt atcaagaaat tacaggagcc
      661 attatgtcta ctaccgttaa accttctgca gacgcagctg cgatccacaa tacccgtgaa
      721 gcagttcgca gccagcctgg cctgggtaac ctgactttcc agatgaaagc ccgttccagc
      781 ggcggattaa ccgttcgcac agagaccggc gccacaatcc agaacggcgt tatcgatacc
      841 agtcgcgtgg ggaaattttc taatatcggt gatgaacccg caggtttact cggcaccgat
      901 accggcatga gcccgactga atacatcatg caggcgctgg ctggctgtta taccgccacc
      961 ctcaccatga tggctgctga aaaagggatc gacctggacg gtatcgagct ggatcttaat
     1021 ttcgatatca acctcaacgg cttccttggg ctggacagca acgtgcgtaa aggtgcgaaa
     1081 tctattcgcg tcgatgttca ccttacgagc aagaccgcca gtcgcgagga gttagaagcg
     1141 ctggtcagcg aaatgcaaaa gaattcgcca atccacgata ctctggctaa tccggttgaa
     1201 atgattacac gcctggcgtg atgtcagaga tgtaatgctg ccattcagaa tgcaggatgg
     1261 cagtgacgtt cagctctgca cgatactgag tcagtgatac aacttgctac ggaaaaatag
     1321 caataatata atctatcaac tagtagatta tatggagtga ttatgacaac catgacacgg
     1381 gaacggctgc tcagcgaagc agaacacctg atgcgcgaaa aagggtattc agcattcagc
     1441 tatgctgatt tatcaaaaat agtgggtatc accaaggcca gtattcatca ccatttcccg
     1501 accaaagata ttctgggtga gcaggtggta atacaggcgt tctctgatac acaacgcgta
     1561 tttgagcaga tagaggcgac tgagaaaagc gcggagagaa gaattgcggc ttacatcgat
     1621 atcttcgcgc aaagccataa agcttcgcta ctgccactgt gttgtgcgtt gtcagcagag
     1681 accgccaatc tgcctcaggc aattactgta cagacatcac tttatttcga tatgcaaatc
     1741 gagtggctca caaaagtcgt cagggcgggc atggagtcag gtgagttttc atcccatgcc
     1801 gaaccatcag atattgcttt gatgatcatt aatgtctgtg aaggctcaag cgtagtggcg
     1861 catgcaacgg ccagacccga agtcttcgcc aacagcctta agtatataaa actgcttctt
     1921 aatacccctc attcaggaga atgacactat gctggactgg aacaactatc gctcagagtt
     1981 aatgcaacgt ttaggcgagt tgggcaaact gacccccgag accatgaaag gcgtggttgc
     2041 cctgggcaac gcaggtaaca aaactgacct tttgggcgca aaagtgcgag aactcattgc
     2101 cctggcgtgc gcagtcacaa cccgctgcga cggctgtatt gcttttcacg ccgacgccgc
     2161 tgtgaaagcc ggtgcaaccg acgctgaaat tgctgaagcg ctgggcgtgg cgattaacct
     2221 caacgctggc gcggcggtca tttattcagc ccgcactctg gatgccgtcg gtcaggcacg
     2281 cggttaagca ttaataaatt ccatgttaaa agggcattac tgcccttttt ttatgtccgc
     2341 aatagcctga gcatataccg atgcaggttt cacacccggt atgcgtttaa ctaattgccc
     2401 ttcatgaaat atcagcacag acggcagccc ccagatctcg tatttggttg tcagcaccgg
     2461 cgcctgatct acattgactt tccccacctg aatatctcta tcgagccggt ctgcaaactg
     2521 actgaacatt tcttcgctgg cctgacaggg cggacaccag ggtgcagaga aacgtaccac
     2581 cgatattcct ttgtactgct ctatctggcg gaaattatct tcgttataag ctgttaatgt
     2641 acgcatggtg atgacctcgc aaaatgagtg acaattcaga aatggctgcg ttatgacaaa
     2701 aaaatacgac acagccattg acctacctac tagatggttg gtatattgcc acccatcaga
     2761 tgtttatgca actccagtgc gcgacgtcca gtcgatgata ctgccgggct gtgcaaatcc
     2821 ctgccgggat actccttttt gttttttgtg aggtatacga tgagtaagct tttcaccccc
     2881 tacaatctgt ctggcctggc gttaaaaaac cgtgtagtca tggcaccgat gacccgcacc
     2941 cgcaccatga atgaggtgcc ggatgaggtc gtggctttgt actatgcaca gcgtgcttct
     3001 gctggcctgc tcatcaccga agggatgccg gtttcagaag aaggccgggg ttacctttat
     3061 acccctggta tctacaacga cgaacacgtc cagggctggc gtaaggtgac acaagcggtt
     3121 cacgccaaag gtggccgtat tttcgcgcag ctctggcacg tcggccgtat gtctcacgtc
     3181 tctcttcagc caggccacat agcgccggtt tcagcgggca ccgttcaggc ggtcaatacc
     3241 accgtttttg cgctgaccga atccggagaa ccgggcccgg ttgtaccaag ccagccacgc
     3301 gcgctggaaa cgcatgaagt taaacgcatc actgcagact tcgtgcactc cgcacgcctg
     3361 gcgatggaag ccggctttga cggcgtggaa atcatggcgg caaacggatt catctttgac
     3421 cagttcctca gtagcgaact gaacacccgc accgacgaat acggcggctc ggtggaaaat
     3481 cgtcagcgtt tcctgctgga gaccattgac gccgtggcgg aagccgtggg taacagccac
     3541 gttgccgtgc gcctgtcacc gttcggccgc atttatgacc tcgcgccgta tgaaggtgaa
     3601 gagcaaacct ggtcagccat caccgacgcg ctcggtcagc gggaactggc ctacgtacac
     3661 ctttactatc agccggtgta caccaaagcg ccacttccgg aaggcttccg ccgccgtttt
     3721 cgcaacacgt ttaaaggcac catcatcgct gccggcggtt ttacccgtga tatcgcagag
     3781 caggctctgg aagatgatga gctggatctg gtggcatttg gtgtgcccta catcgctaac
     3841 ccggatctgg ttgaaagaat gcaaaacggc tggccactgg cagaaagtga ccgcgccacc
     3901 tactacggcg tcagtggttc cccggaaaaa ggctataccg attacccggt ctggcaggcg
     3961 caataaatcc catacggtcg cggttctctg atcagtgaga tccgaccgcc caacgtcttt
     4021 gaggaatcat tatgcaaacg ctgaaacaca cccttaccat cgatatctgg tcagatttgg
     4081 tctgcccgtg gtgctggatt gctaaaaaaa gatttgaaca gggtctgaat cgctttgaat
     4141 ttcgcgacca ggtggtgatc cgccatcaca gctaccgtct ggccggtggt actcccgcga
     4201 tgccttttaa ggatgccatc gttaaaaagc tgggcagtca gcattcagcg gagctgatga
     4261 tggatcaggt gggcaccgcc ggtaaatctg aaggtctgat ctacaacttc gacggcatga
     4321 tgtttggtga tacagaagat gcacacaccc tgctggttgc cgcgcgtaag gccggaattg
     4381 cggacgcagt ggaagaacgt ttttatcacg gcagtatcac cgaaggtcgc tctctctttg
     4441 accgtcagca gctcgttgca atggccgtag aagccggtat ggagaaagct gacgccgaag
     4501 ccgctctgga aaatgacgat tttcgcgcca ccgtttccga cgatgaagcc cacgcacagt
     4561 ctattggcct cagcggcgtt ccggtttttg tgatgaacga gaaatacgcc atcagcgggg
     4621 ctcagggggc agacaacttt ttgaatgccc tgcgtcaggt ctgggatgaa cagcaaaccg
     4681 aattttcagc cactgcgggt cagacctgcg gaacggatgg ctgcagcatt taatccgtca
     4741 accgccggca gtttcacgct gccggcaacg tcttacccac cagtaatgga gtctgaaaat
     4801 gaatacattt ttcaaaggta aaaaactgct tgtcgtcggc ggcaccagcg gcatgggtct
     4861 cgccgtggca cgcatggtac tggaagcggg cggcagtgtg gtgctgaccg ggaataaaaa
     4921 agacaaagcc gaagcggtac aaaaagagct gggcccgctg ggaccggtgg cggtcatcgc
     4981 ggccaacctg atgactgaag aaggtatgga aactatccgt catgaaatca atgccagcca
     5041 tcgcgatatc agcctgatgg taaatgccgc cgggatcttt atgccgaaag ggtttaccga
     5101 gcacagcttt gccgattatg acatgtactt ttcgctgaac cgcgccacgt tctttattac
     5161 gcaggatgtc gtgaagaaca tgctcgccgc gaagctcgaa gggtctatcg tcaacgtcgg
     5221 ttcgattggt gcccaggcag cactggggga ctcgccgtcc tcggcctatt caatggcaaa
     5281 agcgggtctg catgccctga cgcgtaatct ggcgattgaa ctggccagcg cgggtattcg
     5341 tgtcaacgct gtgtctcccg ggattgttca tacaccaata tacgaaggct tcatggacaa
     5401 agcggatatc gctgatgcta tgaagtcgtt gaacgatttc cacccgttag gccgcgtcgg
     5461 aaccgcagag gatgtggcaa acaccattct cttcctgttg tctgacaaaa catcatgggt
     5521 gacgggcgct atctgggatg tcgatgccgg cattatggcg gtcagacgat aaccccggta
     5581 cgttgacaag agccgcccct ttacgggcgt catttttttg tcgccagaaa tgtcatcagc
     5641 aggcttcact caggatattc acaacctgtt catccgtgcc ttttttgttc ccggcacagg
     5701 gtgttatgcc gggttctgac gacatcctga caggacaaac ggccagagag aaaggggtta
     5761 taccctgtta ggggccggtg tccgcagtac ctgtgaaatt cttttcatcc ctgctgtcag
     5821 catagtccgt gggcacgcca gatttaaccg gatatgtcct tccccattgt cgacaaacag
     5881 caagccccct tcaagaagca cccctgactc ccgggcaaaa tacagcgata aatcctcacc
     5941 cacagtgtcg ggcaggtagt ggctaatatc tatccaggcc agatatgtcc cttcggggat
     6001 cgagaacctg gtttcgggta aatagctttt gaggtagtcg tgcaggtact ggaaattgcc
     6061 gtcaatatat tccctcagat ggacaagcca gtcatcgcat tcactccacg ccgctttgtt
     6121 tgctgccagg ctcagcggag agatgaactc gtcgtgtctg agacgccact cgcttctgac
     6181 accgggatcc ggaataatga tatttgccaa caaattcccg gccagattga atgttttact
     6241 cgaggacatg caggtaataa tgcgtgtaga atcagggaaa agagaggcgg ccggtgtatg
     6301 accgatacca cttcgggaca ggtcacagtg aatttcgtca gatatcaccc agatatcatt
     6361 ggccaggcaa atttcaataa tccgcttaag ttcatcaggc cgccagactc gtccggtcgg
     6421 gttatgcgga ttacacagga aaagaatttt cacacgtaag tcggcctgac tggctttgcg
     6481 tgtaaagtct tcccagtcag gttcccagcc acctgctgat ttttttaacg ccgagtacac
     6541 cacgcgacgc tgactgtatt cacccgcctt tttaaacggg ccatatgaag gcgtcataat
     6601 aagaatactg tcatccttgt cggtcagaag cgggacgaga cggttcagcg cgggaataat
     6661 gcccggagac agtacaatgt cttccgtttt gaaacggtga ccatattgtc gctcacacca
     6721 gttgccaaag atttcatagt attcttcgtc gtagatttta gtgtagccga gtatttttct
     6781 atccagacgg tctctgatgg cctgaagaat cggctctggt gtggcaaaag ccatgtcagc
     6841 aacccagagg ttgattagcc cttctgccgg ataccgcatt gcaaattcgg actgccccgc
     6901 aaacaggtat tcccgccagc cgtccacggt aagactgtct gttttctctc tgcttacgta
     6961 ctcatcaaaa tcatatttca tttcatgaac ctgccttagg tgtagtctga aacgtcgacc
     7021 tcagtattcc tgtcagtctg atgccggagc gggaaaactg gctcgtgtga ttaacataag
     7081 agaatcatta caactgcatg aattaattgc gttattgagg ttttctcgcc tttgccatcg
     7141 gctgacgggg ggatttctcg cgtgtcacca tcacaatgcc agtcagcact gccagggcag
     7201 aaaatatcgt tctgaccgtc agtgattcac ccaggaatac cacaccccct agcattgcca
     7261 ggcagggaac gctgagctga aggatactgg cggtaataga gccgagggag ggtaaaaggg
     7321 tataccacaa tacataggca ccggctgagg cgacggcacc ggacagcaat gacaaagcaa
     7381 tgcctgcagc atcagagtga ccctgcttca taaacagcaa cgtaagagcg agagccatcg
     7441 gcgctgcgag aataaaatta gccgccgttg aagccccggc agcctggccc gccctccccc
     7501 tgacggaata ggcggcccag gctaatccgg aaacgatcat cataagtgca ctgtaaagcg
     7561 gcggtgcctt cgtcccgggt aacagcaggg cagcaattcc cgtcagagcc agaactaaac
     7621 cgcaagcccg catagcggag agtgattctc ctttaaataa tccgtggatc accatcgcaa
     7681 actgtacggc accaaaaagt aacagcgcac cagccccggt atcgagatgg atataggcga
     7741 cagaaaacag caccgcatac gccatgaggt aaaacccgct cagcggacgc cacagcgata
     7801 atgtggtcct ggcgtgataa aagaggaagg gggacaggac gaatgcacca ctggccagcc
     7861 tgaggctgct gaatgaaagg ggatcaatgt ggcctccctg cagggccaga cgacacagaa
     7921 tggagtttgc cgcaaatgcc agcattgcca gtgatatttt aagaatgagc gcgcacctgg
     7981 ccattcgaga agtcctcaca aaagccttgt aaactaccat ctagttggta gcatagcgta
     8041 agtgatcgcc gagcaggaag caataaccag cttccaaact ggaaggtgag gacaggcatt
     8101 cggaatgaat tctgtttcac atccccagtg gaggacggaa aacgcgttat gccagatgca
     8161 gagcagaaga ttatttttct cctgcgatca aacatatgac atcagtttaa ggcccggaat
     8221 atcctatgaa aaaactaaaa tttacgttca aaaatgcggc gggtgaagaa ctggccggat
     8281 tgcttgaact tcctgaaaat cctaaagcgt ttgcgctgtt agctcattgt tttacgtgtg
     8341 gcaaagacct caaaggcgcg gcgcgtattg cgcggaaact gacagagaaa gctatcgccg
     8401 ttctccggtt tgattttact ggtctgggaa acagcgaagg ggatttttcc aacaccaact
     8461 tctcatccaa tatttcggac ctgctttgcg cggtagatta tctccgccga cagtacgaag
     8521 cgccttcttt gctcatcggt catagcctgg ggggatcggc catcctgtct atcgccggcg
     8581 aagttcctga ggcaaaggcc attgtcacca taggatcacc cggagaactg acacacgtaa
     8641 aacgtctttt taaggatgat gttgaaaaca ttaaccagca tggagcctat cccgttgagc
     8701 tggccgggcg ggtatttacg ttaaagaaac agatgctgga caatattcag gaacacaaaa
     8761 tcgctcataa ggtgttcgcc atgaacaaac ctctgctgat ttttcatgcg actgaagatg
     8821 ataccgtgtt aattgagcag gccgagaaaa tattcaaagc agctaagcat cccaagagtt
     8881 tcatttccct gggtaaggct gatcaccttc tgacacatgc tcaggatgct gaatacgttg
     8941 ccgatatcat tatatcgtgg agcgaatgtt acctataaac agagtaaatg cgttcaaact
     9001 cgtagcgctg agggcgattt tctgcagaga tcggacgctg tttatgctgg actgattttg
     9061 cgataaaggc ttaggccgat gcatacaggc ggggctgaat aagggtgagg cccttgggcg
     9121 agcatccttc atgcaccggc tgaatgaaat cagggatctg ggggtgggag gatcagcgtt
     9181 accacgccac cggcgctgac actacatacg gcggcgataa cactctggaa tacggtttat
     9241 atagaaagaa ccattgagcc gcttaagcaa aaaggagtcc ctgttaatga actgctggtc
     9301 tctcatcctt ctccactgct gtacaaaata tagtcttagc gtgggataat ttccgttttc
     9361 caagcggacc ccttgtatct ggctttcacg aagccgaact gccgcttgat gatgcgaaac
     9421 gggtgctcca ccttggcacg gatgctggct ttcatgtatt cgatgttgat ggccgttttg
     9481 ttcttgcgcg gatgctgctt caaggttttt accttgccgg gacgctcggc gatcagccag
     9541 tccacatcca cctcggccag ctcctcgcgc tatggcgctc cttggtagcc ggcatcggct
     9601 gagacaaatt gctcctctcc atgaagcaga ttacccaact gattgaggtc atgctcgttg
     9661 ccgcggtggt gactaggctg tgggtcaggc cactattggc atcgacacca atgtgggcct
     9721 tcatgccaaa gtgccactga ttgcctttct tggtctgatg catctccgga tcgcgttgct
     9781 gctctttgtt cttggtagag ctgggtgcct caatgatggt ggcatccacc aaagtgcctt
     9841 gggtcatcat gacgcctgct tcggccagcc agcgattgat ggtcttgaac aattgacggg
     9901 ccagttgatg ctgctcgagc aggtggcgga aattcatgat ggtggtgcga tccggcaggg
     9961 cgctatccag ggataatcgg gcaaacaggc gcatggaggc gatttcgtac agggcatctt
    10021 ccatggcacc gtcgctcagg ttgtaccaat gctgcatgca gtgaatacgc agcatggtct
    10081 ccagcggata gggccgtcgg ccattgcccg ccttgggata aaacggctcg atgacagcgg
    10141 tcatattctg ccatggcaga atctgctcca tgcgggagag gaaaatctct tttcgggtct
    10201 gacggcgctt agtgctgaat tcactatcgg cgaaggtgag ttgatggctc atgatgtccc
    10261 tctgggatgc gctccggatg aatatgatga tctcatatca ggaacttgtt cgcaccttcc
    10321 ctaattgaag caccggatgg taccgatttc agtatgttct cggcaataag ccagaaaacg
    10381 gggctcagta acgtaacacc gatacttggt actagtgata acggtaacgg tacaaatctg
    10441 gcaattattg gctttaactc agagcctgat aaaaaagcag tcagtacggc ggccagtttt
    10501 gctaatagca gctaccgcct tttctctaca gaaatgaata acctcaataa acgtatgggg
    10561 gacattcgcg acagtggaga agccggggtc tggggacgct atatgctcgg tcaggggagt
    10621 ggcactgacg gttatcagaa tacatacaac cacctgcaac tcggtgcaga caaaggcata
    10681 agaattgaat cagcaatgct atacactggc ttaatattta cccatacaag taccaatgca
    10741 gagctgagcg gcagctatta tggcgatact aaaagctatg gtctgggtgg gtatacgtcc
    10801 atcttctttg ataacggttt ttatactgat tttatcgcta aatacatcca ttcaacaaac
    10861 gtttatagct atttaagtcc aagtgaaccg ccccgggttt cctggagagt gttttatctg
    10921 tgaactcagg ctgccagatc atcgtttccg atggaagcat aataagcttt ttctgcttct
    10981 gccggaggag tatggcccag cctttccagc aatcgtcgat tgttatacca gtccacccac
    11041 gtgagtgtgg ccagttccac ttctgcacgg tttttccagc tcttacggtg tattacctcc
    11101 gctttgtaaa gaccattgat gttctccgcc atcgcgttgt catacgagtc gcctgtactt
    11161 cctgttgatg ccagtaatcc ggcttcctta agccgctgtg tgtaggccag cgatacatac
    11221 tgagaacctt tatcactgtg atggaccgtg ccggacggtc gacgggccca taacgcctgc
    11281 tccagtgcat ccagcacgaa tgtcgtttcc atggacgatg agacccgcca ccccacgatg
    11341 tatccggcaa acacatcaat gatgaacgcc acatagacga ccccctgcca tgtgctgagt
    11401 agagtaagag gcagggcgta gtcggactat ttccctgcct ctcctccccg aaccggacgt
    11461 gcacctttca gcgcatccgg ctctccattt aaatgctggc gaacgccatt gccacttctg
    11521 taaagcgcga tgtatacgtg tttctggtct ccgtcctcag atagggatta ccttcgggta
    11581 gccgccagcg gaacagcttc ttgccttgcc ccaccaaccg gtacagtatt tcgccgctga
    11641 gcttgccgtg attggtttta ccaaataaaa cccacgtttt gctctgaccc ggtttcggtg
    11701 atttacacca ccacctcatc agggaagcga tacctgtacg gtatttgcgg gccagccagt
    11761 gagccagctt ccagaacacg acacggtcga tataactgaa gactttggcc ttaaaatcaa
    11821 cgaactgata gaacatggcc cagcctttca gttttcggtt gagttgttca gccatatcga
    11881 ctttgctttc actgtagttg cctgataaca gtgctgtcag cgatgcggcg aagtttctgg
    11941 ctttctcctg cgggatcgtt gagaccactc gcatctcgcc ataacgactg cgtttgcgaa
    12001 tgatcctgtg ccccagaaag ataaagccgt cattaacatg ggtgatttta gtcttatcca
    12061 tgttcagcct gagtttcaga ctgccttcga gcacaccccg acactcctcc ctgatggctt
    12121 ccgcctgtgc tttggtgcct ttgacgatga ggacaaaatc atcggcatag cggcagtacg
    12181 ccaccgcggg tttccactgc cagttttctc tgaccgccgt acttcggccc cgttggatac
    12241 tgttattcca gtaccaccga tcttttctgg ctttcccgct caggtagcgc tcatgcaggt
    12301 attgatcgaa ctcattcagc atgatgttcg ataatagcgg cgatataaca ccgccctgtg
    12361 gcacaccttc actggccgcc cgaaagagac cgacatcgat atgtcccgcc ttgatggttt
    12421 tccacagcag agtcatgaaa cgtgcgtcac tgatcctgcg gcgtacagcc ttcatcagca
    12481 gtcgatgatg tacggtgtcg aagtaactgg acaggtcgcc ttcaatcacc cagcgtcccc
    12541 gggtttcacc acagtctgtg agctgtaatt tcaccgtgcg gatcgcgtgg tggacactgc
    12601 gctcaggccg gaagccatat gagagcgtat gaaaatcact ctcccatatc ggctccatcg
    12661 ccatcagcat ggcccgctga acaatacgat cccgcaacgc ggggataccc agtggtcgca
    12721 gtttgccgtt gcttttaggg atgtaaaccc gtctggcggg caagggctgg tagtggcctg
    12781 agagtaattc atccctgagg atttgcagct caacagccag tctggcctgt agcattgttt
    12841 tgttcacgcc atcaacgccg ggggtatggg ccccctttga tgaaagcgtg atccgcgccg
    12901 cttcagccag ccattctggt tgtgttatca gacgcagcag ccgttgaatc cgtagggacg
    12961 gatcggtgac tgcccatgtg gcaagcttgc gttgcatttc gctgattatc aaaggtcttc
    13021 acctcgttag gtcagttaat tcacgtcgca aacacattca aactgcttcc cttcgccatg
    13081 taatgggctt tccccatcgc ggactactac ggaagctccg ccagccagcg cgtcatcgga
    13141 gccatgcccc cttaacatcc gtcgctgacc ttccccggtt tacctgcctg gactcaggca
    13201 tactgaggag gctgcccgtc gcactcttta tccttgcttg ccgcaagttg gcagaagtca
    13261 gcaacgcaag cgtgatagac gctgctgccc cggtgtttcg catacatgtc aaaacacctt
    13321 cgaccggcag tgcttacgta tcactgccag ttcctcctgc acggcctgtc agatcacgta
    13381 ggccgtggtg acgttttcaa cccacagagg cggattaacg ggttcatgtt cttcagcctt
    13441 tcagtactta accttgagga tcatctcggc ttagtgatct cgcctcaatc cccgttgtca
    13501 gcgggttaca tcaccctgcg ggcatgccgc aggtcactgc cgctcaggtt ctccaccgtc
    13561 acacccggtg ggattgttgg gtttctcatc gtgagttacc ggctcaatat tccagacaga
    13621 ctcgcggttc atttaagcat ccatgcccgc cctgaactcc gggcaca
//
LOCUS       DAFGPF010000128        13605 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFGPF010000128 DAFGPF010000000
VERSION     DAFGPF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13605
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.128"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            913..2136
                     /locus_tag="LSX49_004247"
     CDS             913..2136
                     /locus_tag="LSX49_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HBL7170569.1"
                     /translation="MGTIQKIRTDVNVLYAAIHRIEWLFETFSSVCLSFSGGKDSTVL
                     LHLTADVARRKKRRFSVLFIDWEAQYQCTIAHILKMREMYRDVTETFYWVALPLTTVN
                     GVSQFQPEWICWEPGVEWVRQPPDDAITDMSYFPFYRYAMTFEEFVPAFSSWFAGNRC
                     GVAILTGVRADESLNRFMGLVSQRKLRYADDKPWTTASPEGFYYTLYPLYDWKARDIW
                     IYNARTRAIYNPLYDLMYRAGVPLRNMRVCEPFGPEQRKGLWLYHVLEPETWARMCER
                     VSGAASGALYANESGAYFALRKRITKPPHHTWRSYAMFLLDVMPERTAEHYRNKIAVY
                     LRWYQTRGFPDDIPDEQENDLGSRDIPSWRRICKTLIKNDFWCRTLSFSPNKPRHYER
                     YLQRMKERRKEWGIL"
     gene            2121..2765
                     /locus_tag="LSX49_004248"
     CDS             2121..2765
                     /locus_tag="LSX49_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HBL7170570.1"
                     /translation="MGDSVTPEVEVLSNMIRQYFSQERSEEETIRALNHLRRVLHEVS
                     PFAQEPVDCVLWVKADEVVANDYNPNVMSSSEKKLLKHSLEQDGFTQPVVVSEEKEHY
                     LVVDGFHRQLLGRKADTRKRLKGWLPVTCINPERKGQASRIAATIRHNRARGKHQITS
                     MSDIVRDLSRLGWTDERIGTELGMDQDEVLRLKQISGLTELFQEENFSPSWTVR"
     gene            complement(3136..5283)
                     /locus_tag="LSX49_004249"
     CDS             complement(3136..5283)
                     /locus_tag="LSX49_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBL7170571.1"
                     /translation="MLYNIPCRIYILSTLSLCISGIVSTATATSSETKISNEETLVVT
                     TNRSASNLWESPATIQVIDQQTLQNSTNASIADNLQDIPGVEITDNSLAGRKQIRIRG
                     EASSRVLILIDGQEVTYQRAGDNYGVGLLIDESALERVEVVKGPYSVLYGSQAIGGIV
                     NFITKKGGDKLASGVVKAVYNSATAGWEESIAVQGSIGGFDYRINGSYSDQGNRDTPD
                     GRLPNTNYRNNSQGVWLGYNSGNHRFGLSLDRYRLATQTYYEDPDGSYEAFSVKIPKL
                     EREKVGVFYDTDVDGDYLKKIHFDAYEQTIQRQFANEVKTTQPVPSPMIQALTVHNKT
                     DTHDKQYTQAVTLQSHFSLPANNELVTGAQYKQDRVSQRSGGMTSSKSLTGFINKETR
                     TRSYYESEQSTVSLFAQNDWRFADHWTWTMGVRQYWLSSKLTRGDGVSYTAGIISDTS
                     LARESASDHEMVTSTSLRYSGFDNLELRAAFAQGYVFPTLSQLFMQTSAGGSVTYGNP
                     DLKAEHSNNFELGARYNGNQWLIDSAVYYSEAKDYIASLICDGSIVCNGNTNSSRSSY
                     YYYDNIDRAKTWGLEISAEYNGWVFSPYISGNLIRRQYETSTLKTTNTGEPAINGRIG
                     LKHTLVMGQANIISDVFIRAASSAKDDSNGTETNVPGWATLNFAVNTEFGNEDQYRIN
                     LALNNLTDKRYRTAHETIPAAGFNAAIGFVWNF"
     gene            6955..7500
                     /gene="cobU"
                     /locus_tag="LSX49_004250"
     CDS             6955..7500
                     /gene="cobU"
                     /locus_tag="LSX49_004250"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBL7170572.1"
                     /translation="MMILVTGGARSGKSRHAEVLIGDSSQVLYIATSQILDDEMAARI
                     EHHRQSRPEHWRTVERWQHLDELIHADINPNEAVLLECVTTMVTNLLFDYGGDKDPDE
                     WDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
     gene            7497..8240
                     /gene="cobS"
                     /locus_tag="LSX49_004251"
     CDS             7497..8240
                     /gene="cobS"
                     /locus_tag="LSX49_004251"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBL7170573.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLVFMVLQAWCGVPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIEFGELVFLLALL"
     gene            8252..9331
                     /gene="cobT"
                     /locus_tag="LSX49_004252"
     CDS             8252..9331
                     /gene="cobT"
                     /locus_tag="LSX49_004252"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBL7170574.1"
                     /translation="MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAI
                     QLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
                     RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVV
                     RRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGSGAALAMSIIEAACA
                     IYNNMGELAASNIVLPGNTTSDLNS"
     gene            9393..10328
                     /gene="ldtA"
                     /locus_tag="LSX49_004253"
     CDS             9393..10328
                     /gene="ldtA"
                     /locus_tag="LSX49_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HBL7170575.1"
                     /translation="MMRRVNILCSFALLFASQNSLAVTYPLPPEGSRLVGQSLTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKPGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGKLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSKWLEVHEPLSRNRAEYESDRKVPLPVTPSLR
                     AFINGQEVDVNRANAALQHRSGMPVQISSGSRQMF"
     gene            complement(10384..10459)
                     /locus_tag="LSX49_004254"
     tRNA            complement(10384..10459)
                     /locus_tag="LSX49_004254"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10424..10426),aa:Asn,seq:gtt)
     gene            10786..11703
                     /gene="nac"
                     /locus_tag="LSX49_004255"
     CDS             10786..11703
                     /gene="nac"
                     /locus_tag="LSX49_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="HBL7170576.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN
                     QQLLIRTKRGVTPTGAGKILYTHARAILRQCEQAQLAVHNVGQSLSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEVVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAVRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVISSPVMEKRQWQLVS"
     gene            11805..12755
                     /gene="cbl"
                     /locus_tag="LSX49_004256"
     CDS             11805..12755
                     /gene="cbl"
                     /locus_tag="LSX49_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HBL7170577.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPLDHPLTQITPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLPA
                     DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEKNLIRLDTRHLFDANTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKRQVMENSEEEIDYQI"
     gene            complement(12793..12868)
                     /locus_tag="LSX49_004257"
     tRNA            complement(12793..12868)
                     /locus_tag="LSX49_004257"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12833..12835),aa:Asn,seq:gtt)
     gene            12873..>13605
                     /locus_tag="LSX49_004258"
     CDS             12873..>13605
                     /locus_tag="LSX49_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN/FAD transporter"
                     /protein_id="HBL7170578.1"
                     /translation="MLRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSF
                     ADSPSSFEMWFHFLQLRSALNISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIF
                     MENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLG
                     KRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTDVKALALTYLEL
                     TVFSYPAAAITLIGSGALRGAGNTKI"
BASE COUNT         3501 a         2848 c         3419 g         3837 t
ORIGIN      
        1 ttcatttctg ttaaaaaaac agagtttata tgctattacg gatttcagtc gtagcaagtt
       61 gaactgtgat cgcattaaga ctaatcttct ggcttgtaaa ggccttagtt ccgtcatgac
      121 tctcccatca ggccatagtt gagcaaaatc ctgaaagaat tatcacctat tgtatcttca
      181 gatacgggag tttttgtcca gtattgttgg aataatcatg tgactatatt gttcttgtag
      241 ttggaacgtc ttataaataa aacgaaaagg cagtaagttt gttgtattta ttgatatttt
      301 tcattcagtt agttggcaat aatcagttat ggttgtattc aaaagtacag ctagaacgaa
      361 attaaaataa cgggagcatc gtacatgact tgatatttca gagggctaag tattaatata
      421 ttactacgat ctgtcatcat tgactatcaa tatattagtt agttaaatat ctctttgtgt
      481 cattctggct agtatatact cattatcatg aatgctgcca tgcatagcta ggtcatcacc
      541 aattaatgat attctctgga taatgattca agagtttaag ttcattgtat atataagttt
      601 gtattcaaag gtaataaatt ccttgtttat tatttctcat gaaaatagtt aagaaggagt
      661 gaagagtctg tttttttggt aggagagtct ttatttatgt gtttgctatt aatgaatttt
      721 tgttaaggta gcctcatttg tcataatttt gctaatatat gtatcgtcat atgtcgtgtt
      781 ttactaaaaa cttaactatc atgaactcgt gatagtaaca atataccctt aaggtagaac
      841 tttttcttga tgagaaggtt taagtttgta gttcagaata ttactgccaa gatagtttat
      901 actaggatat gtatgggaac catacagaag ataagaacag atgttaatgt attatatgcg
      961 gccattcacc gtattgagtg gttgtttgag acattttcat ctgtttgttt gtctttttct
     1021 ggaggaaaag actctactgt gctgctccat cttacggccg atgtggctcg caggaagaaa
     1081 cgtcgtttct ctgtattatt cattgactgg gaagctcagt accagtgcac aattgcacac
     1141 attctgaaga tgagggagat gtatcgggat gtgacggaga ctttttactg ggtggcactc
     1201 cccctgacta cggtaaacgg tgtctctcag tttcagccgg aatggatatg ctgggaacca
     1261 ggtgtggagt gggttcgtca gccaccagat gacgctatta cagatatgtc gtatttccca
     1321 ttttatcggt atgccatgac gtttgaagaa tttgttccgg cattttcttc ctggtttgcc
     1381 ggtaaccggt gtggagtggc aatactgact ggtgttcgtg ctgatgaatc gctcaatcgc
     1441 tttatgggac tggtgtctca gcgcaaactg agatatgcag atgataaacc ctggaccaca
     1501 gcgtcacctg aagggtttta ttacaccttg tatccgttgt atgactggaa agcccgtgat
     1561 atatggatat ataacgccag aacccgagct atctacaatc ccctgtatga cctgatgtac
     1621 cgtgccggcg tgccgttacg caacatgcgg gtctgtgagc cttttggccc ggaacagcgt
     1681 aagggactgt ggctttacca tgttctggag ccggaaactt gggccaggat gtgtgagcgg
     1741 gtgtcgggtg ctgccagcgg ggcgctttat gccaatgaga gcggtgccta ttttgccctg
     1801 cgtaagcgta tcacgaagcc acctcatcat acctggcgta gctatgcgat gttcctgctg
     1861 gatgtgatgc cggaaagaac ggcagaacat taccgtaata aaattgctgt ctacctgcgc
     1921 tggtatcaga cgcggggctt cccggatgac atcccggatg aacaggagaa tgacctgggg
     1981 agccgggata tcccgtcttg gcgacgtatc tgtaagacac tcataaagaa tgatttctgg
     2041 tgccggaccc tctccttcag tccgaacaaa ccccggcact atgaacgtta tctgcagcgt
     2101 atgaaagaaa ggaggaagga atgggggatt ctgtgacacc tgaggtggaa gtattgagca
     2161 acatgattcg acagtacttc agtcaggaac gatctgaaga agagaccata cgagccctta
     2221 atcatctgcg cagggtgttg catgaggtca gcccttttgc acaggagcct gtggactgtg
     2281 tgttgtgggt gaaagcggat gaggtggtgg ccaacgatta caatcccaat gtcatgtctt
     2341 ccagtgaaaa aaaactgctt aaacattcac tggagcagga tggattcacg cagcctgtgg
     2401 tggtttcgga agagaaggag cattatctgg tcgtggatgg ttttcatcgt cagttgctgg
     2461 gcaggaaagc ggatacgaga aaacgtctga agggttggct gccagtgacc tgtattaatc
     2521 cggaaagaaa gggacaggca tcacgtattg ccgcaaccat acggcataac cgtgccaggg
     2581 gaaaacacca gataacgtca atgtctgaca ttgtcaggga cctttcgcgt ctgggctgga
     2641 cagatgagcg tattggcaca gagttgggca tggaccagga tgaagtgctg aggctgaaac
     2701 agattagcgg gctgacagag ctgtttcagg aagagaattt cagcccttca tggacggttc
     2761 gttgatattg taaaatatga tagttggagt aaggggcaat agaaggagaa tatttatccc
     2821 accttcttcc gagtcgggat aaatcaaaag gtattatcca ttgattcagt atctgggtga
     2881 gagtaaataa tctaaaaata gtattgcgtt gtgaactgat atcacttttg aattacaaag
     2941 gtataggctc agtaaccagc tttataagtc attgtcgtag caatgactat agagtcatgc
     3001 tggcgggaag aataaatatt cacccccaga tggaaaacaa cgtcgaaaaa ccttcaacaa
     3061 acacaatacg ttcgttagcc tgcccgcaaa gcgggcagat caggacaaag aattccataa
     3121 cgattgtttt tgtcatcaga aattccatac aaaacctata gctgcattaa aacctgctgc
     3181 aggaatagtt tcatgtgctg tacggtagcg tttgtctgtc aggttattga gtgctaggtt
     3241 aatccggtac tgatcctcgt taccgaattc tgtatttact gcaaagttga gagtggccca
     3301 gcccggaaca tttgtttcgg taccgttact gtcatctttt gcactagagg cagcacgaat
     3361 aaaaacatca gagattatgt tggcctgacc catcacaaga gtatgtttca gccctatacg
     3421 tccgtttatc gctggttctc ctgtattagt tgtttttaat gttgaagttt catattgccg
     3481 acgaattaaa ttgccactga tatatggcga gaaaacccag ccattatatt ccgcgcttat
     3541 ttccagtccc catgtttttg cccgatcaat attgtcataa taatagtagc tactacggga
     3601 ggagttggtg ttaccattgc aaactatact gccatcacag atcagacttg caatataatc
     3661 tttagcttct gagtagtaaa ctgcgctgtc aatcagccac tgattaccat tatatcgtgc
     3721 acctaattca aagttattgg agtgttcagc cttaagatca ggatttccgt atgtgacact
     3781 gccgcccgca gatgtctgca taaaaagctg ggagagtgtg ggaaatacgt agccttgcgc
     3841 gaacgcagcg cgtaactcca agttatcgaa acctgaatag cgcaggcttg tagatgttac
     3901 catttcgtga tcactcgcag actctctggc aagagaggta tcgcttataa tgcctgcggt
     3961 atatgatact ccgtcaccac gcgtcaactt tgaagaaagc cagtattggc gaactcccat
     4021 tgtccatgtc cagtgatcgg cgaatcgcca gtcattttgt gcgaatagtg agactgtact
     4081 ttgctctgac tcataatagg agcgagttcg tgtttcctta ttaatgaagc cggtcagaga
     4141 tttgcttgag gtcatgccac cggacctttg gctgaccctg tcttgtttgt actgtgcacc
     4201 ggtaacaagt tcattattag caggcagcga aaagtgactc tgcaatgtga ccgcctgagt
     4261 gtattgctta tcatgggtgt cagtcttgtt atgaacggtc agagcctgaa tcatcggact
     4321 gggaacaggc tgtgtcgttt ttacttcgtt ggcaaattgg cgctggatgg tctgctcata
     4381 cgcgtcgaaa tgaatttttt ttagatagtc accgtccacg tctgtgtcat agaatacccc
     4441 aactttctct cgttcaagtt taggtatttt gacactaaat gcctcatagc ttccgtctgg
     4501 atcctcatag taagtttgcg tcgcgagtct gtagcgatca agcgagaggc caaaacgatg
     4561 gtttccggag ttataaccca accatacacc ctgactattg ttacgatagt tggtattcgg
     4621 cagacgtcca tccggcgtat cacgattgcc ctgatcagaa taactaccgt tgatgcgata
     4681 atcaaatcca ccgatgctcc cctggaccgc gattgattct tcccagcctg ctgttgcgga
     4741 attataaaca gctttcacaa ctccagatgc aagtttgtca cctccctttt tggttatgaa
     4801 gttaacaata ccgccaattg cctgtgaacc gtacagtacg gaatatggac ctttcactac
     4861 ctcaacacgc tccagcgcag actcatctat caacagtccc acaccataat tatctccggc
     4921 gcgctgataa gttacctcct gaccatcaat gagaattaaa acacgggagg atgcttcgcc
     4981 acgaatgcgg atttgtttac ggcctgccaa ggagttgtct gttatctcta ctccggggat
     5041 gtcctgcaaa ttatcggcta tggaggcatt ggtggagttc tgcaatgttt gttggtcaat
     5101 aacctgtata gtcgccgggc tttcccaaag gttgcttgcc gaacgattcg tggtcacgac
     5161 gagcgtctct tcgttgctga tttttgtttc tgaagaagtt gcggttgcag tagaaactat
     5221 cccagaaatg cataatgaca gagtggaaag gatataaatt cgacaaggta tattatataa
     5281 catttcatcc ctcattaata caaagtacaa atgattgctg taatgataat tattatcatt
     5341 tatgttctca tgtatctgtg attattgtca tcttcataaa ttgtaaatat caaacatttt
     5401 tgaccttaat catgtttttt gatagatatt ttacgactga acatatccgt cgtttcctct
     5461 gactcgtgtc agtcggtctc tggttgtatc cacggaccgt actcttgaca taagagtgcg
     5521 gtccgtggaa aacggagttg aaaaaatggt gtctgaaaga aggtaccatc attgcgatga
     5581 caaacacttt ggcgtggata atgtaattaa ttgctgaaat tgaccgtata tgcggtaaga
     5641 ctcatatcag tatcaggtcc ggttaattgc tgatactgac ataaactttt tacaaaagga
     5701 tgaatgcaga aggttactct aatggccaga gtgatgacaa tgatggtcag acgttgacct
     5761 gcagaaactg cattttaatt ggtctataaa gtctgcaaga ggaatcaggg tcagatcagt
     5821 gagtcttatc gcggcccgaa gctatgactg aaagaaggct ggatacagaa ttgcaacaat
     5881 ttggcaatgt cagaacacag aagctttgca agcaggtgaa aggttatgtc tagaaaaagg
     5941 agtatatcag aatacatcta ctgatgtaca aaacacaaca atagcttcat gatatataaa
     6001 tacgtgatga cgagttgtac tccgcatggt tatttaactt ctcagcacca ctaatgatcc
     6061 tgagcaactt cgtatttggg ccattgccat ggagtagaaa gctgtgtctg agaatgcaga
     6121 atttgagaaa agaattcgct ttcttggaga gcttctgaaa atggcacgct aacaacgctt
     6181 tgttaaaaaa tgtgaatcac ttgccgaggc tgcattttct attcgaggag aatgttgacg
     6241 tagatattac agaaatctca gcgcatcagg ataaactgct accttaggtc aaccaccaaa
     6301 agaaaataca atacgtccag tttgtatgcc tttaataaca catcttttaa atgttgaaga
     6361 attatcccgc ctgctgaaga acgttgctct gagtgtgata aaccttttta ttcttgatga
     6421 tgtcagcgag aagatggaat atatccccga ctgggtcgtg gttacccggt taaacatctg
     6481 gtggcgctaa taaatctggc aagtcacatt ctgttgaatg ctgtgacagt gccttaccga
     6541 gagagcgaaa ttgtggtgtt ctagtgcata gtcgccacca ttccggataa ttttattgcg
     6601 ttgttttaca acttctttta cagcgcagat ctgtcgctga cgttgaatca atagcctgga
     6661 tttcagaaca caatgcccgt ttgctggttg gtccggcagt agcattaatt cattatctga
     6721 atgaaatgtg tcaatccaca gaaaccgctg tcaatgacgc attttgtcgg acgttaacac
     6781 gagaaagtct ggctattccg taatgccatc ttatttcgta atggattgag aatgctggat
     6841 ttttaattat attacgcgca gtattaatcg cgtaaatgtt ttgcggtcag caacggtggg
     6901 ggatccattg ctctgttcaa tgaataccat catacatttg aatcaggagt cggtatgatg
     6961 attttggtga cgggaggcgc acggagcggg aagagtcgcc acgcagaggt gcttattggg
     7021 gactcttcac aggttctgta tatcgctacc tcgcaaatcc ttgatgatga gatggctgca
     7081 cggatagaac atcatcggca aagccgcccg gagcactggc gcacagtgga gcgctggcaa
     7141 catcttgatg aattaattca tgcagacatt aacccgaatg aggctgtgtt gctggaatgc
     7201 gttaccacaa tggtgactaa tctgttgttt gattatggcg gcgataaaga ccctgatgaa
     7261 tgggattatc aggcgatgga acaggcgatt aatgctgaga ttcagtcgtt gattgctgcc
     7321 tgccaacgtt gccccgcaaa ggttgtatta gtgactaacg aagtgggaat ggggattgtg
     7381 ccggagagtc gtctggcacg acattttcgt gatattgccg ggcgggtaaa tcagcagttg
     7441 gccgctgcgg caaatgaagt atggctggtg gtttcgggta ttggagtaaa aatcaaatga
     7501 gtaaattatt ttgggcgatg ctctcattta ttacgcgtct gcctgtaccg cgtcgctggt
     7561 cccagggact ggatttcgag cattattctc gcggtattat tacttttcct ttgattggat
     7621 tattgcttgg cgcgattagc gggctggtct tcatggtgct gcaggcatgg tgtggcgtac
     7681 cactggcggc actgtttagc gtacttgtgc tggcgctgat gaccggggga ttccatctgg
     7741 acggcctcgc tgatacctgt gatggcgtat tttctgcacg tagccgcgat cgcatgttgg
     7801 aaatcatgcg tgatagccgt ttaggcaccc acggcggtct ggcattgatt tttgtggtac
     7861 tggcaaagat tctggtgtta agcgagttgg ctctgcgtgg cgaaccgatc cttgcatcgc
     7921 tggcggcagc atgtgcggtc agccgcggga ctgccgcatt attgatgtat cgtcatcgtt
     7981 atgcgcggga agaagggctt ggcaatgtgt tcattggcaa aattgatggg cgacaaacct
     8041 gcgtcacact cggcttagcc gctatttttg ctgccgtatt attgccgggt atgcatggtg
     8101 tggctgctat ggtggtgacg atggtggcga ttttcatcct cggtcagctt ctcaaacgta
     8161 cgctgggcgg gcaaacgggc gatacgctgg gagcagccat agagtttggt gaactggttt
     8221 tcctgctggc actgctataa agagacgtga catgcaaata cttgccgatt tactgaatac
     8281 gatcccagcc atcaattctg ccgctatgtc gcgtgcacaa cggcatgttg acgggttact
     8341 caaacctgtt ggtagcctgg gaaagctgga ggcgcttgcc atacaactgg caggaatgcc
     8401 ggggttgaat ggcataccgc atgtgggcaa aaaagcagta ctggttatgt gtgccgatca
     8461 cggcgtctgg gaggaagggg tcgctatttc tccaaaagaa gtgacagcca tacaggctga
     8521 aaatatgacc cgtggaacaa ccggcgtgtg tgtgctggca gcacaagcgg gcgctaacgt
     8581 ccacgtaatt gatgttggta ttgatactgc tgagcctatc cccgggctta tcaacatgcg
     8641 tgtcgcacga ggtagcggca atattgcttc agctccggca atgagtcgcc gtcaggctga
     8701 aaagttgctt ttggacgtca tatgttatac gcgggagctg gcaaaaaacg gtgtcacgct
     8761 gtttggtgta ggtgaactgg ggatggcaaa cacgacaccg gcagcggcaa tagtcagcac
     8821 aatcactggc cgggatcctg aagaagtggt tgggattggc gcaaacctgc cgacagataa
     8881 actggctaat aaaattgatg ttgtgcgtcg ggcgattacg ttgaatcaac caaatcctca
     8941 ggatggtgtt gatgtcctgg caaaagtggg tggatttgat ttggtcggaa tagctggagt
     9001 gatgttaggt gctgcttcct gcggtttacc cgtgttgctg gatggatttc tttcttatgc
     9061 tgctgcgctc gcagcctgcc agatgtctcc tgcaatcaaa ccgtatctca ttccttctca
     9121 cttgtcggca gaaaaaggcg cgcgtatagc gctctcgcat ttggggctgg agccttatct
     9181 caatatggat atgcgtttag gtgaggggag tggtgcagct ctggcgatgt ccatcatcga
     9241 agctgcttgt gcgatataca acaacatggg cgaacttgct gccagtaata ttgttctacc
     9301 ggggaatacg acttctgatt tgaacagcta aaaacgaaaa gtctgataaa agctatactt
     9361 atcggatagt attcgcgact taggaaaggg acatgatgcg tcgtgtaaat attctttgct
     9421 catttgctct gctttttgcc agccaaaata gcctggcggt aacttatcca ttacctccag
     9481 agggtagccg tttagtgggg cagtcgctta ctgtaactgt tcctgatcac aatactcagc
     9541 cgctggagac ttttgccgca caatacgggc aagggttaag taatatgctg gaagcgaatc
     9601 cgggcgctga tgtttttttg ccgaagcctg gctcacaact caccattccg cagcaactga
     9661 ttttgcccgc cactgttcgt aaagggattg tggttaacgt cgctgaaatg cgtctttatt
     9721 actatccgcc agacagtaat acagtggaag tctttcctat tggtatcggc caggctgggc
     9781 gagaaacccc gcgtaactgg gtgactaccg ttgaacgtaa acaagaagca ccaacctgga
     9841 cgccaacgcc gaacacccgg cgcgaatatg cgaaacgagg ggagagtttg cccgcatttg
     9901 ttcctgcggg gcccgataac cccatggggc tgtacgcgat ttatattggc aagttgtatg
     9961 ccatccacgg taccaatgcc aattttggta ttgggctccg cgtaagtcag ggctgtattc
    10021 gtctgcgtaa tgacgatatc aaatatctgt ttgataatgt tcctgtaggc actcgtgtac
    10081 aaattattga tcagccagtg aaatacacaa cggaaccgga tggttcaaag tggctggaag
    10141 ttcatgagcc gctgtcgcgc aatcgtgcag aatatgagtc tgaccgaaaa gtgccattgc
    10201 cggtaacccc atctttgcgg gcgtttatca acgggcaaga agttgatgta aatcgcgcaa
    10261 atgctgcgtt gcaacatcga tcgggaatgc ctgtgcaaat tagttctggt tcaagacaga
    10321 tgttttaaga gcgttggtaa ttagaaagta aaaagcctgc tcgaaagcag gcttttttga
    10381 atttggctcc tctgactgga ctcgaaccag tgacatacgg attaacagtc cgccgttcta
    10441 ccgactgaac tacagaggaa tcgtgtgaac ggggcgcata ttaatggcag tgcatggtga
    10501 tgtcaaaggg tgaaatgcat ttttttgttt gtttgctgac aatttcaaca aagtggtgag
    10561 ctttcaatct tattgggtaa tgaaccatcg tggtgcatac ccccctttta tagggcaggt
    10621 gaatgcgact gctgataaaa agggccaatg acgaatctat cataatctct tatttgacag
    10681 ttggttagct tgcgcatcaa cgctaaaata gaactggcaa gcatcttgca ttctggttgt
    10741 aagtaatggc ggcacttggg ccgattctta aaaaccggag gcaacatgaa cttcagacgc
    10801 ctgaaatact tcgtaaaaat tgtagatatt ggtagcctga cccaggctgc tgaagtattg
    10861 catatcgcac aaccagcgct cagccagcag gttgccacac tggaaggtga gttaaatcaa
    10921 cagcttttga ttcgcacaaa acggggcgtt acgccaacag gcgccggaaa aattctctat
    10981 acccatgcac gggccatttt acgtcagtgt gagcaggccc aactggcggt gcataacgtt
    11041 ggtcagtcat tatcggggca agtctcgatt ggctttgcgc caggaaccgc tgcgtcatcc
    11101 atcaccatgc ccttattaca ggcggttcgc gctgaattcc cggaggtcgt tatctatctt
    11161 catgaaaata gtggtgcagt gcttaacgaa aaactgataa atcaccaact cgatatggcg
    11221 gtgatttatg agcattcccc tgtggctggg gtatccagtc aggctttgct gaaagaagat
    11281 cttttcctgg taggaactca agattgcccg gggcaaagcg ttgatgttaa tgctattgcg
    11341 caaatgaacc tttttctccc cagtgattac agcgctgtta gacttcgtgt tgatgaggct
    11401 ttttccctac ggcggctcac ggcaaaagtc attggtgaaa ttgagtctat tgccacgctt
    11461 accgcagcga ttgccagcgg catgggcgtt gcagtattac ctgaatcggc tgcgcgttcg
    11521 ttatgtggcg cagtaaatgg gtggatgtca cgcattacca ctccttcaat gagtctctct
    11581 ttgtccttaa atttacccgc cagagcaaac ttgtcaccac aggcacaggc agtgaaagag
    11641 ttgttaatgt cagtgattag ttctccagtg atggaaaaaa ggcagtggca attggtgagc
    11701 taagcgttat atcgggatgg aataagatgc gggtttttat tatttgttat gccgggcatt
    11761 agactttaac aataacggga tatctgaact gcccggagtt taccgtgaat ttccaacaac
    11821 taaagataat ccgcgaggct gcacgtcagg attacaacct gacagaggtt gcgaatatgc
    11881 tttttacctc acagtcaggc gttagccgtc atattcggga actggaggat gaacttggca
    11941 tcgaaatatt tgttcgacga ggtaagcgac tgctgggcat gactgaaccg ggcaaagcat
    12001 tactggtcat tgcagaacgc attctgaatg aagccagtaa tgttcgtcgg ctcgcagacc
    12061 tgtttaccaa cgatacgtct ggcgttctca ctattgcaac gacgcatact caggcacgtt
    12121 atagcttgcc tgaggtcatt aaagcttttc gcgaactttt cccggaggtt cggctggagc
    12181 taatccaggg tacaccacag gaaattgcga cgttgttgca aaatggcgaa gctgatattg
    12241 gtatcgccag cgagcgtttg agtaatgacc cgcagctcgt cgccttcccg tggtttcgtt
    12301 ggcaccatag tttgcttgtt ccactcgatc atcccttgac gcaaattaca ccgttgacgc
    12361 tggaatcaat agcgaagtgg ccgttaatta cttaccgaca ggggattacg gggcgctcac
    12421 gcattgatga cgcatttgcc cgcaaaggtt tgccggcaga tattgtatta agtgcacagg
    12481 attctgatgt cattaaaacc tatgttgctc ttgggcttgg gatcggatta gttgccgaac
    12541 aatccagcgg cgaacaagag gaaaagaatt taatccgcct ggatacgcgg catcttttcg
    12601 atgctaatac tgtctggttg ggactgaagc gagggcaact tcagcgtaac tatgtctggc
    12661 gctttctgga actttgtaat gcaggactgt cagttgagga tatcaagcgc caggtgatgg
    12721 aaaacagtga agaggaaatt gattatcaga tatagcaaaa agcccgctat aaaagcgggc
    12781 ttttcagaaa tttggctcct ctgactggac tcgaaccagt gacatacgga ttaacagtcc
    12841 gccgttctac cgactgaact acagaggaat cgctgttgag gcacatctta acggcgaaaa
    12901 atattttgtc aaacccgatt tttaaatttc ccaactgttt gccgtttcta tcaacagttt
    12961 gttgcatttg cagacaattt gttggcgaaa atctttgcag ctttgctgat tctccctcat
    13021 catttgaaat gtggtttcac tttctgcaat taaggtcggc tttgaatatc tcctctgctt
    13081 tacgccaggt tgttcacggc actcgctggc actctaaacg caagagctac aaagtgttgt
    13141 tctggcgcga gataaccccg cttgctgttc ctatcttcat ggagaacgcc tgtgtcctgt
    13201 tgatgggggt cctgagcact tttctggtca gctggctggg aaaagatgcg atggccggcg
    13261 tggggttggc ggacagcttc aatatggtca ttatggcttt ttttgcagct atcgatcttg
    13321 gtactactgt cgttgtagca tttagtctcg gtaagcgaga tcgacgacga gcgagggtgg
    13381 cgacgcggca gtcattggtg atcatgacgt tgtttgccgt actgttggca acgctaattc
    13441 atcattttgg cgaacaaatt attgatttcg tcgcgggtga tgccacgaca gacgttaaag
    13501 cactggcgtt gacttatctg gagctgaccg tattcagtta tccagcagct gccatcactc
    13561 ttattggtag cggggcactt cgtggtgcag ggaatacgaa aatac
//
LOCUS       DAFGPF010000129        13494 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFGPF010000129 DAFGPF010000000
VERSION     DAFGPF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13494
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.129"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..955)
                     /locus_tag="LSX49_004259"
     CDS             complement(<1..955)
                     /locus_tag="LSX49_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006686536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBL7170579.1"
                     /translation="MTNFTTSTPHDALFKSFLTHPDTARDFMEIHLPKDLRELCDLDS
                     LKLEYASFVDEKLRALHSDILWSVKTREGDGYIYVVIEHQSREDIHMAFRLMRYSMAV
                     MQRHIEHDKRRPLPLVIPMLFYHGSRSPYPWSLCWLDEFADPATARKLYTAAFPLVDV
                     TVVPDDEIVQHRRVALLELIQKHIRQRDLMGLIDQLAVLLVTGCANDSQITALLNYIL
                     LTGDEARFNEFISELIRRMPQHRERIMTIAERIHNDGWLLGRERGRKEGKEEGEKSLL
                     RLLLQNGADPEWIQRYTGLSAEQMQALDQPLPESKRDPWIEY"
     gene            1422..2654
                     /gene="mdtM"
                     /locus_tag="LSX49_004260"
     CDS             1422..2654
                     /gene="mdtM"
                     /locus_tag="LSX49_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HBL7170580.1"
                     /translation="MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
                     MHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFL
                     FGAATIALSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQVPVFGAVIVANTIVARFIK
                     DPTEPRFIWRAVPIQLAGLALLIVGNLLSPHVWQWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLA
                     GLLNRVRQHQAAELAEER"
     gene            2695..3975
                     /locus_tag="LSX49_004261"
     CDS             2695..3975
                     /locus_tag="LSX49_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HBL7170581.1"
                     /translation="MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDP
                     EMAARTDAVKSYLKEDEAFNRYLSELWGDLREWLKADINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHHVAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNF"
     gene            4091..5242
                     /locus_tag="LSX49_004262"
     CDS             4091..5242
                     /locus_tag="LSX49_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase subunit D"
                     /protein_id="HBL7170582.1"
                     /translation="MSLVTDLPAIFDQFSEARQKGFLTVMDLKERGIPLVGTYCTFMP
                     QEIPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEMLRLHKTVEERFGHE
                     ISEDALRDAIVLKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLDPRPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLQMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRHQHNIPYIAIETDYSTSDIGQLSTRVAAFIEML"
     gene            5252..6019
                     /locus_tag="LSX49_004263"
     CDS             5252..6019
                     /locus_tag="LSX49_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170583.1"
                     /translation="MAYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLAPATRAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSVEQLDSITENVIPHAITSMC
                     TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQRF
                     THMLESHLGMPVQTHPDAQFAGAIGAAVIGQRQRKRA"
     gene            6016..6273
                     /locus_tag="LSX49_004264"
     CDS             6016..6273
                     /locus_tag="LSX49_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBL7170584.1"
                     /translation="MKEYLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLC
                     IWLTCPPGEEIQWVIPGHTESVYCQQDGGWRCIAHYGISPR"
     gene            6338..7198
                     /locus_tag="LSX49_004265"
     CDS             6338..7198
                     /locus_tag="LSX49_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418753.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HBL7170585.1"
                     /translation="MTKSISLSKRIFVIVILFVIVAVCTFFVQSCARKSNHAASFQNY
                     HATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDLIRTIPLDFVKD
                     LETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQESPTNCGFEGLAYS
                     RQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDKALQRQFTLDDVSGAEFNQQKNTL
                     LVLSHESRALQEVTLAGEVIGEMSLTKGSRGLSHNIKQAEGVAMDASGNIYIVSEPNR
                     FYRFTPQSSH"
     gene            7266..8444
                     /locus_tag="LSX49_004266"
     CDS             7266..8444
                     /locus_tag="LSX49_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170586.1"
                     /translation="MPSPSHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAE
                     GSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWL
                     LPFILVLLIRVLAGVASAGMLIFGSMLIMQHTRHPFVLAALFSGVGIGIALGNEYVLA
                     GLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPC
                     LTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLGNGTSALAGATLCGAAALFIAALISTVQLFKLQVVTS
                     "
     gene            complement(8457..9011)
                     /gene="kptA"
                     /locus_tag="LSX49_004267"
     CDS             complement(8457..9011)
                     /gene="kptA"
                     /locus_tag="LSX49_004267"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HBL7170587.1"
                     /translation="MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKVGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GLPFWQAENGVWLTSTVAVEFLEW"
     gene            9261..9944
                     /locus_tag="LSX49_004268"
     CDS             9261..9944
                     /locus_tag="LSX49_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170588.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            9941..10402
                     /locus_tag="LSX49_004269"
     CDS             9941..10402
                     /locus_tag="LSX49_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBL7170589.1"
                     /translation="MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            10415..11587
                     /gene="iadA"
                     /locus_tag="LSX49_004270"
     CDS             10415..11587
                     /gene="iadA"
                     /locus_tag="LSX49_004270"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL7170590.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPS
                     DIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPVYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLSGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            11652..12563
                     /gene="hypT"
                     /locus_tag="LSX49_004271"
                     /gene_synonym="qseD"
     CDS             11652..12563
                     /gene="hypT"
                     /locus_tag="LSX49_004271"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HBL7170591.1"
                     /translation="MDDCGAVLHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGQLVVLNRDELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(12556..12948)
                     /gene="iraD"
                     /locus_tag="LSX49_004272"
     CDS             complement(12556..12948)
                     /gene="iraD"
                     /locus_tag="LSX49_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418746.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HBL7170592.1"
                     /translation="MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIM
                     LYHDDESLTFDLVWDNGGWRSATLENVS"
     gene            complement(12945..13028)
                     /gene="idlP"
                     /locus_tag="LSX49_004273"
     CDS             complement(12945..13028)
                     /gene="idlP"
                     /locus_tag="LSX49_004273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide IdlP"
                     /protein_id="HBL7170593.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
BASE COUNT         3095 a         3419 c         3424 g         3556 t
ORIGIN      
        1 agtactcgat ccatggatcg cgcttgcttt caggcaaggg ctgatctaat gcctgcattt
       61 gctctgccga aagtccggta tatcgttgta tccattcagg atccgcccca ttctgcaaca
      121 acaatcggag gaggctcttt tccccttctt ctttcccttc tttcctcccc ctctcccttc
      181 ccaacagcca tccatcatta tgaattcgct ctgcaatcgt cattattcgc tccctgtgtt
      241 gtggcattcg acggataagt tcgctgataa actcattaaa acgcgcttca tcgccagtca
      301 gtaaaatgta atttaacagc gcggttatct ggctgtcatt agcgcaccct gtaaccagta
      361 atactgccag ttgatcaata agccccatta gatcgcgctg gcgaatatgc ttttggatca
      421 actccagcag ggcgactctg cgatgctgca caatctcgtc gtctggcacg acagtgacat
      481 ccaccagcgg gaacgctgcg gtataaagct tccgtgcggt agccgggtcg gcaaattcat
      541 ccagccagca caaagaccag gggtaaggac tacggctacc gtgataaaac agcatcggga
      601 tgaccagcgg tagcggccgg cgtttatcat gctcgatatg gcgctgcatc accgccatgg
      661 aatatcgcat caggcgaaag gccatatgga tatcctcgcg gctctgatgt tcaatcacca
      721 cataaatata gccatctcct tcgcgggtct ttaccgacca cagaatatcg gaatgtagcg
      781 cccgcaattt ttcatcgaca aagctggcgt attccagttt taagctgtcg agatcgcaca
      841 gttcacgtaa atctttgggt aagtggatct ccataaaatc ccgcgcggtg tcagggtggg
      901 tgagaaaaga tttaaataat gcgtcatgcg gcgtgctggt cgtgaagttt gtcatggcga
      961 tccgtcacct gtagataaga tggcccgact gtagcgacta acaaaaccat tctcacccgg
     1021 caatttctcg ttccccgagg tgctttccag gctatttttg ttcctctgca aacgatacat
     1081 ttttccggaa acaggctcgc attttacatt tcctgtaccc ggcagatatt cccctttcca
     1141 ccgcactctt ttgattaacc gcaaatttta attacactta aggtgtatat tttctatgca
     1201 acccatcaat tcaagaggtg taatgtgctg atgactattt gtaatcgtta tacattctga
     1261 cctggagtca gaaggtattt ctctgtctgt atgttcacag gcagtgtggt tgattacatg
     1321 aaattcagta catttgcccg tctcgcctgc ctttcgtcat taccgacggt attgaatttc
     1381 gttttcccca ttgggattct ccggacaagg agttgtttgt tatgccacgt ttttttgccc
     1441 gccatgccgc cacgctgttt ttcccgatgg cgttgatttt gtatgacttt gctgcgtatc
     1501 tgtcgacgga cctgatccag ccagggatca ttaatgtggt ccgtgatttt aatgccgatg
     1561 tcagtctggc cccggctgcc gtcagtctct atctcgctgg aggcatggca ttgcagtggc
     1621 tgctggggcc gctttccgac aggattggcc gcaggccggt gctgattacc ggggcgttaa
     1681 tttttaccct tgcctgcgcc gcgacaatgt tcaccacgtc aatgacacaa tttcttatcg
     1741 cgcgtgcaat tcagggcacc agtatctgtt ttattgccac cgttggttat gtcacggtgc
     1801 aggaggcgtt cggacagaca aaagggatca agttgatggc gattatcacc tccatcgtac
     1861 tgattgcgcc gattattggc ccgctttccg gcgcagctct gatgcacttt gtgcactgga
     1921 aagtcctttt tgccatcatt gcggttatgg gttttatctc atttgtcggc ttgctgctgg
     1981 cgatgccaga gacggtgaag cgcggcgcgg ttccgtttag cgccaaaagc gtcttgcgcg
     2041 attttcgcaa tgtcttttgc aaccggctgt tcctctttgg cgcggcaacc atcgccctca
     2101 gctatatccc aatgatgagc tgggtggctg tctcgccggt gatcctgatc gatgcgggcg
     2161 gcttaacaac ttcgcagttc gcctggacgc aggttccggt attcggcgcg gtgattgtcg
     2221 ccaacaccat cgtggcgcga tttatcaaag atccgaccga accgcggttt atctggcgtg
     2281 ccgtgcccat tcaactggcc ggcctcgcac tgttgattgt cggcaatttg ctgtcgccac
     2341 acgtctggca gtggtcggtg ctcggcacca gtctgtatgc tttcgggatt ggtttaatct
     2401 tcccgacctt attccgcttt acgctgtttt ccaataactt accgaaaggg accgtctccg
     2461 catcactgaa tatggtgatc ctgatggtga tgtctgtctc ggtcgaaatc ggccgctggc
     2521 tgtggtttaa cggcggtcgc ttgccgtttc atctgttagc cgtcgtagcg ggcgttatcg
     2581 tcgttttcac cctggcggga ttgctcaatc gcgtgcgcca gcatcaggct gccgagctgg
     2641 cggaggagcg gtgatttttg cgcgatcctg ccgtcaggct ctattcttaa cgttatgaat
     2701 aaactcattg aactcagacg cgccaaaatg ttggcgctct ctttactgct tatcgccgct
     2761 gctacctttg tcgttacgct gtttttgcca cccaattttt gggtgagcgg cgtgaaggcg
     2821 attgctgaag cggcgatggt cggcgcgctg gcggactggt ttgcggtggt ggcgctgttt
     2881 cgccgcgtgc cgattccgat catttctcgt catacggcga ttatcccgcg taataaagac
     2941 cggattggcg aaaatctcgg tcagttcgtg caggaaaaat ttctcgatac ccaatcgctg
     3001 gtggcattga ttcgacgtca cgaaccggcg ttgttgattg gcaactggtt tagtcagcca
     3061 gaaaacgccc gccgcgttgg tcagcatctg ttgcagatca tgagtggttt tcttgaactg
     3121 accgatgatg cgcgtattca gcgcctgctt aagcgcgcag tccatcgggc gattgataag
     3181 gtcgatcttt ccggcaccag tgcgttgatg ctggagagta tgaccaaaaa cgatcgtcat
     3241 caggtgctgc tggatacgct gatcgcacag ttgatcgccc ttctccagcg cgataaatcg
     3301 cgcaagttta tcgcccagca gattgttcgc tggctggaga gtgagcatcc actgaaagcc
     3361 aaaattttgc ccactgaatg gctgggcgaa catagcgcgg agttggtttc tgacgcggtg
     3421 aattctttgc ttgatgatat tagtcgcgat cgtgcgcatc agatccgcca tgcgtttgat
     3481 cgcgccacct ttgccctgat cgacaagctg aaaaacgatc ctgaaatggc agcgcgaacc
     3541 gatgccgtaa aaagctatct gaaagaagat gaagctttta accgctatct cagtgaattg
     3601 tggggggatt tacgggaatg gctgaaagcg gatatcaaca gtgaagattc tcgtgtgaaa
     3661 gaacgcatcg cacgagcggg tcaatggttt ggcgaaacgt taattgccga tgatgccttg
     3721 cgggcgtcgt taaatggtca tcttgaacaa gccgcgcacc acgtcgcgcc tgagttttcc
     3781 gcattcctga cgcgccacat cagcgatacg gtaaaaagct gggatgcgcg ggatatgtcg
     3841 cggcaaatag aattaaatat cggcaaagat ctgcagttta ttcgtgttaa cggtacgctg
     3901 gttggcggat gtattgggct gattttgtat ttgctgtcgc agctcccggc tttgttcccc
     3961 ctcggcaatt tttagaaatc catgaaaaac taagtggcta accgcgagag agatcaaata
     4021 aaccgcacta aaagaatggt aataatgtgg cttcttttca ttatctcccg tggtacgggg
     4081 aaggaaaatc atgtcacttg tcaccgatct acccgccatt ttcgatcagt tctctgaagc
     4141 tcgccagaaa ggctttctca ccgtcatgga tctcaaggag cgcggcattc cgctggttgg
     4201 tacctactgt acttttatgc cgcaagagat cccaatggca gccggtgcgg ttgtggtttc
     4261 actctgttcc acctctgatg aaaccattga agaagcggaa aaagacctgc cgcgcaatct
     4321 ctgcccgctg attaaaagca gctacggctt cggcaaaacc gataaatgcc cctacttcta
     4381 cttttctgat ctggtggtcg gtgaaaccac ctgcgacggc aaaaagaaaa tgtatgaata
     4441 catggcggaa tttaagcccg ttcatgtgat gcaactgcca aacagcgtta aggacgatgc
     4501 ctcacgcgcg ttatggaaag ccgagatgct gcgcttgcat aaaacggtag aagaacgttt
     4561 tgggcacgag attagcgaag atgctctacg cgatgccatt gtgctgaaaa accgcgaacg
     4621 tcgcgcactg gccaactttt atcatttggg gcagttaaat cctccggcgc ttagcggcag
     4681 cgacattctg aaagtagtct acggcgcaac cttccggttc gataaagagg cgttgatcaa
     4741 tgaactggat gcaatgaccg cccgcgttcg tcagcagtgg gaagaaggcc agcgactgga
     4801 cccgcgtccg cgcattttaa tcaccggctg cccaattggc ggcgcagcag agaaagtggt
     4861 gcgcgcaatt gaagagaatg gcggctgggt tgtcggttat gaaaactgca ccggggcgaa
     4921 agcgaccgag caatgcgtgg cagaaacggg cgatgtctac gacgcgctgg cggataaata
     4981 tctggcgatt ggctgctcct gtgtttcgcc gaacgatcag cgcctgcaaa tgctcagcca
     5041 gatggttgaa gaatatcagg tcgatggcgt agttgatgtg attttgcagg cgtgccatac
     5101 ctacgcggtg gaatcgctgg cgattaaacg tcatgtgcgt catcagcaca acattcctta
     5161 tatcgctatt gaaacagact actccacctc agatatcggg cagctcagca cccgtgtcgc
     5221 ggcctttatt gagatgctgt aaggagtggc agtggcatat tcgattggca ttgattccgg
     5281 ctcaaccgcc accaaaggga tcttactggc agacggcgtg attacgcgcc gtttcctcgt
     5341 tccaacaccc tttcgcccgg caacagcaat tactgaagcc tgggaaactc tgcgcgaagg
     5401 gttagaaaca acgccgtttc tgacgctcac cggctacgga cggcaactgg tggattttgc
     5461 cgataaacag gtgacggaaa tctcctgtca cgggctgggc gcacggtttc ttgcgccagc
     5521 aacgcgcgca gtaatcgaca tcggtggtca ggacagcaaa gtgattcagc ttgatgatga
     5581 cggtaacctg tgcgatttcc tgatgaatga caaatgcgcg gcgggcaccg ggcgtttcct
     5641 ggaggtgatc tcgcgcacgc ttggcaccag cgtcgagcaa ctcgacagca ttaccgaaaa
     5701 tgtcataccg cacgccatca cgagtatgtg cacagtgttt gctgaatcag aagtgatcag
     5761 cctgcgctct gcgggcgtag cgccagaagc gattctcgcc ggagtgatta acgcgatggc
     5821 gcggcggagc gccaatttca ttgctcgtct ctcctgtgaa gcgccgattc tgtttactgg
     5881 tggcgttagc cactgtcaaa ggtttaccca catgctggaa agccatctgg gaatgccggt
     5941 acaaactcac cctgatgcgc aattcgctgg tgcaattggc gcggcggtga tcggtcagcg
     6001 gcagagaaaa cgcgcatgaa agagtatctg tttttatttc actccacggt cggcgtcata
     6061 caaacccgca aggcgttgca ggcagcgggc atgacttttc gcgtcagcga tattccccgt
     6121 gatttacgcg gcggctgcgg gttatgcatt tggctgacct gtccgcctgg cgaggaaatt
     6181 caatgggtga tccctgggca tacggaatca gtttattgtc agcaggatgg tggctggcgc
     6241 tgcattgcac attacgggat ttctccgcgt taaggattca ttaagatcgc tacgtatact
     6301 tctcgatatc ttattgattt gccttaaagg gattaccgtg acaaaaagta tttcgttaag
     6361 taaacgcatc ttcgttattg tgattctttt tgtcattgtg gcagtgtgta cattcttcgt
     6421 gcaatcttgc gcccgtaaaa gcaatcatgc agcatcattt cagaattacc acgccaccat
     6481 tgacggcaaa gaaattgcag gcataacgaa taatatctct tcgctgacct ggtcggcaca
     6541 aagcaatact ctttttagca ctatcaacaa acctgccgcc attgttgaaa tgaccaccaa
     6601 tggcgatttg atccgcacaa ttcctctgga ttttgttaag gatctcgaga cgatcgaata
     6661 cattggcgat aatcagtttg tcattagcga tgagcgcgat tatgccattt atgtgatttc
     6721 actgacccca aactcggaag taaaaatcct caaaaaaata aaaatcccgc tgcaggaatc
     6781 cccaaccaat tgcggttttg aaggattggc ctattctcgc caggatcaca ctttctggtt
     6841 ttttaaagag aaaaacccga ttgaggtcta caaagttaac gggctgttaa gtagcaatga
     6901 attgcacatc agcaaagaca aggcactaca acggcaattt actttagatg atgtgtccgg
     6961 cgcagaattt aaccaacaaa aaaatacgct tctggtgctg tctcatgaat ctcgcgcact
     7021 ccaggaagta acgctggctg gcgaggttat aggtgaaatg tcactaacca aaggcagtcg
     7081 aggtttgtcg cataacatca aacaggccga aggggttgcg atggatgcct caggtaatat
     7141 ttatatcgtt agcgaaccaa atcgttttta tcgctttacc cctcaatcat cgcattaaca
     7201 ggctggcatg tttcaccttt ttgttattaa cttgttaaca acaaaaatga caaacaaggt
     7261 taaacatgcc ttcgccctcg catcccgtag aacgcttttc tttcagcacc gcgcttttcg
     7321 ggatgctggt tctgacctta ggtatgggtt taggccgctt cctttatacg cctatgttgc
     7381 ccgtcatgat ggcggaagga tcgttttcat ttagccagct ctcgtggatt gccagcggca
     7441 actatgcggg gtatctggct ggcagtctgc tattttcgtt tggcgcattt caccagccat
     7501 cgcgcctgcg cccatttctg ttggcttctg ccctggcgag cgggttgttg atcctcgcaa
     7561 tggcatggtt gctgccattt attctggtgt tattgattcg cgtcctggcg ggtgtcgcca
     7621 gcgccggtat gctgattttt ggttcgatgc tgattatgca gcacacgcgc catccttttg
     7681 tgctggcagc tttgttttct ggcgttggca ttggcatcgc actgggcaat gaatatgttc
     7741 tggcaggcct gcattttgac ctctcctcgc aaacgttatg gcaaggcgcc ggggcgcttt
     7801 ctggcatgat gctgattgca cttacgcttt taatgccctc gaaaaaacac gccatcacac
     7861 caatgccatt ggcaaaaacg gagcaacaga taatgagctg gtggttactg gctattctgt
     7921 acggcctggc gggatttggt tatatcatcg tcgcgactta cctgccgctc atggcgaaag
     7981 atgcaggctc accattgtta accgcccatc tctggacgtt agtcggctta tcaattgtgc
     8041 ctggttgctt tggctggcta tgggcagcaa aacgttgggg ggctttgccc tgcctgacgg
     8101 cgaatttgct ggtgcaggct atctgtgtgc tgcttactct cgccagcgac tcgcctctct
     8161 tgcttatcat cagcagtctt ggttttggcg gtacctttat gggcacgaca tctctggtga
     8221 tgactatcgc ccgccaactg agcgtaccgg gaaatctcaa tcttttaggc tttgtgacgc
     8281 tcatttacgg cattggacaa atcctcggcc cggcgctgac cagtatgctc ggcaatggaa
     8341 catcggcgct tgccggcgcc actctctgcg gcgcggcggc gttgtttatt gctgcgctta
     8401 tcagcacagt acaattattt aagctgcaag tggtcacttc atgaggagtg tttcccttac
     8461 cactcaagaa attcgaccgc aaccgttgat gtcagccaga ccccgttttc cgcttgccag
     8521 aaagggaggc ctcgtttcgc catttcctgt gctttgacgg ttaaaataac cggcgatccg
     8581 tgtcttgctc ccactttgcg tgccgttgct tcatcagcag agagatgtac gtagtgacgc
     8641 tcacctgcaa tcagcccctg tttttttatc tcgtcaagga aacggcttgc cgtaccgtgg
     8701 tagagaaact gtggcggtgt tttttcggca aaggaaatag cgacctgcga agtcgaatgc
     8761 ccctgaaccg cgcggatgca cctaccatca ctggaataac taaaacgctt tttatcgctg
     8821 gtggcaacca cggtatccag caatgcacgg gttaaccgct tgcccacttt ttgggcacaa
     8881 agtatgagct tatcgatatc cgcccatcct tcacggtcca gtacgatacc aatcgcctcc
     8941 ggtttgtgtc ggaggacaaa acttaaaaac ttgctcgtat ccgccagctc tttttcgttg
     9001 tactttgcca tcgcgttttc gtccctggat tatctgtttt ttatttacta tgtcattgtc
     9061 actgggttta tgaattttct gcaactcaat cctgcgtaga accttttcca cacagcgtaa
     9121 ttttaccgct atgcaaaaaa cgcatagtca gaaacatact tgcattttcc ccatacccac
     9181 atggctgata aggtttttca gctccaggaa ttttcctggc tcaagcaaca cacaaacaca
     9241 aaaaaacaat ggggattgtt atgacacaac aaggggatgc tgtagccggg gagctggcga
     9301 cagaaaaagt gggcattaaa gggtatctgg ctttttttct caccataatc tttttttccg
     9361 gtgttttttc cgggacagac agttggtggc gcgtttttga tttttccgtt ctgaacggat
     9421 cgtttgggca actgcctggt gcgaacggag ccaccacctc gtttcgcggc gcgggtggcg
     9481 cgggggctaa agatggcttt ctctttgcgc tggagctggc accgtcagtc attctctctc
     9541 tggggattat ttcaattacc gatggtcttg gcggattacg cgccgcgcag cagttaatga
     9601 cgccagtgct aaaaccgttg ttgggcattc cagggatctg ctcgctggcg ctgatcgcta
     9661 acctgcaaaa caccgatgcc gccgcaggta tgaccaaaga gctggcgcag gaaggtgaaa
     9721 ttaccgaacg cgataaagtg attttcgccg catatcaaac cagcggtagc gccattatca
     9781 ccaactactt ctcttccggc gtcgcggtgt ttgcctttct gggcacgtcc gtaatcgtac
     9841 ctttagcagt catcctggtg tttaaatttg tcggagccaa cattttgcgc gtctggctta
     9901 acttcgaaga acgtcgcaac ccaacgcaag gagcgcaagc atgacaactc aggtccgcaa
     9961 aaacgtcatg gatatgttta tcgatggtgc gcgccgtggc tttactatcg ccacgaccaa
    10021 cctgctgcca aacgtggtga tggcgtttgt catcattcag gcgctgaaaa ttaccggcct
    10081 gctcgactgg gtggggcata tctgtgaacc cgtaatggcg ctgtggggat tacccggtga
    10141 agcggcaacc gtccttttag ccgcattaat gagtatgggt ggcgcagtcg gtgttgccgc
    10201 cagtctggca accgctggcg cattaaccgg tcacgatgtc accgttttac tgcccgcgat
    10261 gtatttaatg ggcaacccgg tgcaaaatgt cggtcgctgc ctggggacag ccgaagtgaa
    10321 tgccaaatat tacccgcata tcattacggt ctgcgtgatt aacgcattgc tgtcgatctg
    10381 ggttatgcag cttattgttt aacaaggagt taccatgatt gattataccg cagccggttt
    10441 taccctgctg cagggagcgc atttgtatgc gccggaagat cggggaattt gcgatgtcct
    10501 cgtcgctaac ggcaaaatta tcgccgttgc cagtaatatc ccttctgaca ttgtaccgga
    10561 ctgcacggtt gtcgatctca gcgggcagat cctctgccca ggttttattg atcaacacgt
    10621 ccatttgatt ggcggtggcg gcgaagcagg tcccacgacg cgcacgccgg aagtggcgtt
    10681 aagtcgtctg acggaagcag gcgtcacgtc agtggttggt ctgctgggca ccgactctat
    10741 ctctcgccac ccggaatccc tgctcgccaa gacccgtgcg ctcaatgaag aaggcatcag
    10801 cgcctggatg ctgaccggcg cttatcatgt cccttcccgc actattacgg gttccgtgga
    10861 aaaagacgtg gcgattatcg atcgcgtgat tggcgtgaaa tgcgccatct ctgatcaccg
    10921 ttctgccgca ccggacgttt atcacctggc taatatggcg gcggaatccc gcgttggcgg
    10981 tttgctcggc ggtaaacctg gcgtcaccgt gttccacatg ggcgacagca aaaaggcgtt
    11041 acagcctgtc tatgacctgc tggaaaactg cgatgtgccg attagcaagt tgctgccgac
    11101 ccacgttaac cgcaacgttc cgttgtttga gcaggcgctg gagttcgcgc gcaaaggcgg
    11161 caccatcgat atcaccagca gcattgacga accagtcgcc cctgccgaag gtattgcccg
    11221 cgccgttcag gcgggtattc cgctggcacg cgtcaccctc agctccgacg gcaacggtag
    11281 ccagccgttc ttcgatgacg aagggaattt aacccatatc ggtgttgccg gttttgaaac
    11341 gttgctggaa accgtgcagg tgctggtcaa agattatgat ttcagtatca gcgatgccct
    11401 gcgcccgctc accagtagcg tagccggttt ccttaacctg agcgggaaag gcgaaattct
    11461 gccaggcaat gacgcagact tactggtcat gacgccagaa ttacgcattg agcaggtata
    11521 cgctcgcggc aagctgatgg tcaaagacgg caaagcctgc gtgaaaggaa cgtttgaaac
    11581 ggcataaacg gttgtcagcc gcccgaatgg acgtagaatg cccgcaaggg cggctgacag
    11641 agtaaaacgt aatggatgac tgtggtgcgg ttttgcataa tattgaaact aaatggcttt
    11701 atgattttct gaccctggaa aaatgccgca atttttccca ggcagcagtc agtcgcaacg
    11761 tctcgcaacc ggcattcagc cgccgcatcc gtgcgctgga acaggcgatt ggcgttgaat
    11821 tgtttaaccg ccaggtgacg ccgctgcaac tctcggaaca aggtaaaata ttccattcgc
    11881 agatccgcca tctgttgcaa cagttagaga gcaaccttgc agaactccgt ggtggcagcg
    11941 attacgcgca acgcaaaatt aaaatagccg ctgcacactc tctttccctc gggctgttac
    12001 cgtccattat cagccagatg ccgccgctct ttacctgggc aattgaagct attgatgtcg
    12061 atgaagcggt cgataaactg cgtgaagggc aaagtgactg tattttttcc tttcacgacg
    12121 aagatttgct ggaagcgccg tttgaccaca ttcgcttatt tgaatctcaa ttgttccccg
    12181 tttgcgccag tgacgaacac ggagaagcac tttttaacct cgcgcagcca cactttccgt
    12241 tactgaatta cagccgcaac tcctacatgg ggcgattgat taatcgcacc ctgacgcgcc
    12301 acagtgagtt aagtttcagc accttttttg tctcttcgat gagcgagctt ttaaagcagg
    12361 ttgccctcga cggctgtggg attgcctggc taccggaata cgccatccaa caagaaattc
    12421 gcagcgggca gctcgttgta ctgaatcggg acgaactggt gatcccgatt caggcctatg
    12481 cataccggat gaatacccgc atgaatccag ttgccgaacg cttctggcgt gaactgcgcg
    12541 agctggagat tgtgcttagc tgacattctc cagcgtcgca ctgcgccaac cgccattatc
    12601 ccagaccaga tcaaacgtta gcgattcatc gtcgtgatac agcattatct caaggctgat
    12661 cgccagagtg tggcagtacg cttctttcaa attaacctgt aacgccgcaa tccgtggctc
    12721 atgaaataac agtgcagaac gcagctgacg gcaataccag ctctggagat gtttgtcgct
    12781 cgggttatgc acttgccact cgggcatgcc tgaaacaagt aatgacggta atgccgaatg
    12841 aggagaatta aaaagagtga ggagatcgct gcatactgat ttacgcagcg gtgacgtttt
    12901 attgcctgaa atttcaggta aaacagcctg aagtgattgg cgcatcattt tgcgcactcc
    12961 tgacgtttag caacatatgc ggcttgccct gaacaccggg caccactgta ttgatgctca
    13021 ttttccatag ccattccctt ttgttcatta catccatgtc agtctgagac aggcctgaat
    13081 cctgtcagca aagtataaaa ccttacttgc ctatgaatat ctactgactt ttcaggaaaa
    13141 aagtcatgat ttgataaaaa tcatcaaact caaaaaaaaa ccgctagtat attctgaata
    13201 ttccgaatag ttacgtagat gaaaatactt gtcaccaccg ctacttaatt ccggtgggaa
    13261 attatttatt tccgcataat cagctatgta ttatttaaaa caattagttt gtaaataata
    13321 taaattgata acatatcaaa tacatcaaaa ataccattca caggcattat taatatagac
    13381 atcaatatag caacatcaaa ttccaattag taataagata tgcttttaaa ttgcatgcaa
    13441 ataattttaa atgagcgttt tttgatactt tagagtgttt cccaccattt aata
//
LOCUS       DAFGPF010000130        13324 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFGPF010000130 DAFGPF010000000
VERSION     DAFGPF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13324
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.130"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(57..1067)
                     /gene="ruvB"
                     /locus_tag="LSX49_004274"
     CDS             complement(57..1067)
                     /gene="ruvB"
                     /locus_tag="LSX49_004274"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBL7170594.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MS"
     gene            complement(1076..1687)
                     /gene="ruvA"
                     /locus_tag="LSX49_004275"
     CDS             complement(1076..1687)
                     /gene="ruvA"
                     /locus_tag="LSX49_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBL7170595.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
     gene            complement(1826..1891)
                     /gene="yobI"
                     /locus_tag="LSX49_004276"
     CDS             complement(1826..1891)
                     /gene="yobI"
                     /locus_tag="LSX49_004276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response small protein YobI"
                     /protein_id="HBL7170596.1"
                     /translation="MYIFITHFFAEYVIFKYLLPI"
     gene            1962..2564
                     /locus_tag="LSX49_004277"
     CDS             1962..2564
                     /locus_tag="LSX49_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HBL7170597.1"
                     /translation="MNINYPAEYEIGDIVFTCIGAALFGQISAASNCWNNHVGIIIGH
                     NGEDFLVAESRVPLSTITTLSRFIKRSANQRYAIKRLDAGLTEQQKQRIVEQVPSRLR
                     KLYHTGFKYESSRQFCSKFVFDTYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFL
                     GSIPWERKTVTPASLWHHPGLVLIHAVGVETPQPELTEAV"
     gene            complement(2566..3087)
                     /gene="ruvC"
                     /locus_tag="LSX49_004278"
     CDS             complement(2566..3087)
                     /gene="ruvC"
                     /locus_tag="LSX49_004278"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBL7170598.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(3122..3862)
                     /locus_tag="LSX49_004279"
     CDS             complement(3122..3862)
                     /locus_tag="LSX49_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL7170599.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(3891..4343)
                     /gene="nudB"
                     /locus_tag="LSX49_004280"
     CDS             complement(3891..4343)
                     /gene="nudB"
                     /locus_tag="LSX49_004280"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HBL7170600.1"
                     /translation="MTDMAYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(4336..6108)
                     /gene="aspS"
                     /locus_tag="LSX49_004281"
     CDS             complement(4336..6108)
                     /gene="aspS"
                     /locus_tag="LSX49_004281"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBL7170601.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILERTGAQDGDMI
                     FFGADNKKIVADAMGSLRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            6418..6984
                     /locus_tag="LSX49_004282"
     CDS             6418..6984
                     /locus_tag="LSX49_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL7170602.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPVALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILHAL"
     gene            6981..7799
                     /locus_tag="LSX49_004283"
     CDS             6981..7799
                     /locus_tag="LSX49_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBL7170603.1"
                     /translation="MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKP
                     EVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQL
                     PATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVIL
                     DSRPVHAARPHSEAIRYAQRKKPKVPVHAVLTAKNPLIRFIGSDDMTQNRELFQVWLQ
                     KLAQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            7852..8247
                     /locus_tag="LSX49_004284"
     CDS             7852..8247
                     /locus_tag="LSX49_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HBL7170604.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            8288..9031
                     /gene="cmoA"
                     /locus_tag="LSX49_004285"
     CDS             8288..9031
                     /gene="cmoA"
                     /locus_tag="LSX49_004285"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HBL7170605.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HKAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            9028..9999
                     /gene="cmoB"
                     /locus_tag="LSX49_004286"
     CDS             9028..9999
                     /gene="cmoB"
                     /locus_tag="LSX49_004286"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HBL7170606.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPTQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVS
                     VTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP"
     gene            complement(10035..12464)
                     /gene="torZ"
                     /locus_tag="LSX49_004287"
     CDS             complement(10035..12464)
                     /gene="torZ"
                     /locus_tag="LSX49_004287"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310609.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine N-oxide reductase TorZ"
                     /protein_id="HBL7170607.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRW
                     GAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDHIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKNDNTPKSAAWAAEITGVPEAQ
                     IVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYS
                     NGGNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQ
                     TYPNIKMIWWAGGGNFTHHQDTNRLIKAWQKPEMIVVSECYWTAAAKHADIVLPITTS
                     FERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKPGGKEIYTEGKDE
                     MAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYIRYGDFRADPVK
                     NALGTPSGKIEIYSRTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLH
                     SQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLVRVWNKRGQILTGAVVTDGIK
                     KGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNALK
                     LTAFDQPAIQA"
     gene            complement(12489..>13324)
                     /locus_tag="LSX49_004288"
     CDS             complement(12489..>13324)
                     /locus_tag="LSX49_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HBL7170608.1"
                     /translation="DIYHEFVSGKIDSDDKFEAHRQEMAETVWKELKATDSATCRSCH
                     SFDAMDISSQSESAQKMHNKAQKDGETCIDCHKGIAHFPPEIKMDDNAAHELESQAAT
                     SVTNGAHIYPFKTSRIGDLATVTPGTDLTVVDVSGKQPIVRLQGYQMQGSENTLYLAA
                     GQRLALATLSEEGIKALTVNGEWQADEYGNQWRQASLQGALTDSALADRKPLWQYAEK
                     LDDTYCAGCHAPIAADHYTVNAWPSIAKGMGARTSMSENELDILTRYFQYNAKDITEK
                     Q"
BASE COUNT         3075 a         3543 c         3260 g         3446 t
ORIGIN      
        1 agcgtcgcat caggcacact gccagtgtcg gatgcggcac gagcgaccaa tccgacttac
       61 gacatttctg gcggcgttat gccaaagtga ttccacgccc gcgtcgtcgc catacgccca
      121 cgcggtgtac gctgcaaaaa gccttgctga atcaaataag gttccagtac atcctcaatg
      181 gtttcacgtt cttcgccaat ggctgccgcc aggttatcca gacctaccgg cccgccaaag
      241 aacttatcga ttaccgccag caacaatttg cggtccatat aatcgaaacc ttcagcatcg
      301 acattcaaca tatccagcgc ctgagcagcg atatctgccg agatggtgcc atcgtgcttc
      361 acttcggcga aatcacgcac tcgacgcagc agacggttgg caatacgtgg cgtaccgcgc
      421 gcacgacgag caacttccag cgcgccgtca tcactcatct caagccccat aaagcgtgcg
      481 ctgcgactga cgatatattg cagatccggc acctgataaa actccagacg ttgcacaata
      541 ccaaaacgat cgcgcaacgg tgatgtcagc gaacctgcgc gcgtggttgc accaatcagg
      601 gtaaacggcg gcaaatcaat tttaatggag cgtgccgccg gaccttcacc aatcatgata
      661 tccagttggt aatcttccat tgccggatac aacacctctt ccaccactgg tgaaagacgg
      721 tggatctcat caataaacag tacatcgtgt ggttcaaggt tagtgagcat tgctgccaga
      781 tcgcccgcct tttccagcac cggaccagaa gtcgtgcgta aattaacgcc catttcattg
      841 gcgacaatat tggcaagcgt agttttaccc aaccccggag gaccaaaaat caatagatga
      901 tcgagggcat cgccgcgcag tttcgctgct ttgatgaaaa tctccatctg cgaacgaacc
      961 tgcggctgac caacatactc ttccagtaat ttagggcgaa tggcgcgatc tgccacatct
     1021 tccggcaaag tggtaccggc agaaatcaga cggtctgctt caatcatcct ttacctcata
     1081 acgcggcgcg tagggcttcg cgaattaatg tttcactgct ggcgtcaggg cgagcgattt
     1141 tgctcaccat gcggcttgct tcttgtggtt tatagcccag tgccaccagc gcagcaaccg
     1201 cttcctgttc agcatcgtcg gtcgccgggc tggcaggaga cgtgagtacc aggtcggcgg
     1261 ctggcgtaaa gagatcgcca tgcaaacctt taaatcggtc tttcatttcg acaatcaaac
     1321 gttcggcggt ttttttgcca atacccggca gtttcaccag tgcccccact tcttcacgct
     1381 caacggcatt aacgaactgc tgcgctgaca ttccggagag gatcgccagc gccaacttcg
     1441 ggccgacgcc gttggttttg atcaactctt tgaacaacgt gcgctcttgt ttattgttaa
     1501 aaccgtacag cagttgcgcg tcttcacgca ccacaaagtg ggtgaaaacg atcgcttcct
     1561 gacccgcttc agggagttca taaaaacagg tcatcggcat atgcacttca tagcctacgc
     1621 cgcccacttc aattaacacc agcgggggtt gtttttcaat gatgatgcct ctgagtctgc
     1681 ctatcacatg acgctcctgc gtaatgaatc aaagataatg ctgtatgata aaaaaatgct
     1741 ggatagatat ccagcgaagg atgaagaaaa cttgcgaggt gtctcgatga tctgaaaaat
     1801 ggcgcagtat aatttattct acaggttata ttggaagcaa atatttaaat attacatatt
     1861 cagcgaagaa atgtgtaata aaaatataca ttgcgactcc tgaaaaaata aattttttat
     1921 gctattacgt atattcatat ctatttcaat ggaatgacaa cgtgaatatt aattatcctg
     1981 cggaatatga aattggtgat atcgtcttta catgtatagg tgctgcctta tttggtcaaa
     2041 tatcagctgc atcaaattgc tggaataatc acgtcgggat cattatcggt cataacggtg
     2101 aagactttct ggttgcagaa agccgtgttc ccctctcaac catcactacg ctatcccgtt
     2161 ttattaaacg ctctgctaat caacgctatg ctataaagcg attagacgcc ggactaacag
     2221 aacaacaaaa acaacgaatt gttgaacagg ttccttcccg gctacgcaaa ctttaccaca
     2281 ccggttttaa atacgaatct tcgcgacagt tctgttcaaa atttgttttt gatacttata
     2341 aagaggcgct atgtattccg gtgggtgaaa tagagacgtt tggagaatta ttaaatagca
     2401 atccgaatgc aaaactcact ttctggaaat tctggttctt aggttctatt ccgtgggagc
     2461 gtaaaaccgt cacgccagcc agtttgtggc atcatccggg tttggtgttg attcacgcgg
     2521 tgggagttga aacgcctcag cctgaactga ccgaggcggt ataacttaac gcagtcgccc
     2581 tctcgccagg ttcagtcgcg attcactcat ttgcatcgca ttctgactaa cgtggcagtg
     2641 ggtgatggca atcgccagcg catcggcggc atccgcctgt ggattagcgg gcagtttcag
     2701 caaggtgcgg accatatgct gcacctggct tttttcggca ctaccaatac ctaccactgt
     2761 ttgctttacc tgacgtgccg catattcaaa taccggcaat tcctgattca ccgccgccac
     2821 aatcgccacg ccgcgcgcct gccccagttt cagggctgag tcagcgttct tcgccataaa
     2881 gacttgttca atggcgaaat aatcaggctg gaattgggtg atgatttccg tcacgcccgc
     2941 atagatgagc ttcagacgag acggtaaatc atccactttg gtgcgtatgc atccgctacc
     3001 caggtaggac agttgcctgc ctacctggcg gatgacgcca tagccggtca cgcgcgaacc
     3061 cgggtcaata ccgagaataa tagccatcac gcgtctccgt tttgctgttt agcaggcctc
     3121 atcagagagt cgctgcaacc tcatcagaga tttcaccgtt atggtaaact tcctgcacgt
     3181 cgtcgcaatc ttccagcata tcgatcagac gcatcagttt cggtgcggtt tctgcatcca
     3241 tatcagcttt ggtggacggg atcatggaaa cttccgcgct gtctgctttc agacctgccg
     3301 cttccagagc gtcgcgtact ttgcccattt cttcccatgc agtgtagaca tcaatcgcgc
     3361 cgtcatcata ggtcacaacg tcttcagcac cggcttccag ggctgcttcc atgatggtgt
     3421 cttcatcgcc tttctcgaag gagatcacgc cttttttgct gaacagataa gctacggaac
     3481 catcagtacc gaggttaccg ccacatttgc tgaatgcatg acgcacttca gcaacggtac
     3541 ggttgcggtt gtcagacaga cattcaatca tgattgccgt gccgccagga ccgtaacctt
     3601 cgtagatgat ggtttccatg tttgcatcat catcaccgcc cacacctcgt gcaattgcgc
     3661 ggttcagagt gtcacgggtc atgttgttag acagtgcttt atcaattgct gcacgcagac
     3721 gcggattagc gtccggatca ccaccgccca gcttagccgc ggttaccagc tcacgaatga
     3781 ttttagtgaa gattttaccg cgcttagcat cctgcgcagc tttacgatgt ctggtgttgg
     3841 cccatttact atgacctgcc ataaaaatat ctccagatag ccctgcctgt tcaggcagcg
     3901 ttaattacaa actgttcaat cgcctgccgg ttgctccagg acttagtgag cgccgccgca
     3961 gcaggcgcat caagccactt gtaagccaga tgttcagtga aaacgatctg gcgctcgtgc
     4021 gggagcgcaa gacagaacca tgattccgta ttacgcgtca cgcccggcgc atagcgatga
     4081 cgtaaatgtg aaaaaatttc aaactctacc gtgcgctgac agtcaattaa ggtcagttgt
     4141 tcagcgacaa catcaatggt gacctcttcc tttacttcgc gcatggcagc ttgcggcgcg
     4201 gtttcaccct cttccacgct gccggttacc gactgccaga aatcgggatc gtcacgccgc
     4261 tgcaacatca gcacccgttt cgtatcttgt gcgtagatga ccactaagat cgaaacggga
     4321 cgcttataag ccatatcagt tattctcagc cttcttcaca acctgaatgc tcagctcagc
     4381 cagtgcagtc gggttagcaa agctcggtgc ttcagtcatc agacacgccg ccgccgtggt
     4441 tttcgggaag gcgataacgt cacggatatt gtcggtgccg gtcagcagca tggtcagacg
     4501 gtcaagaccg aatgccagac ctgcgtgcgg cggagtaccg tatttcaggg cgtcgagcag
     4561 gaagccgaat ttctcgcgct gttcctcttc gttgataccc agaataccaa acaccgtctg
     4621 ctgcatatca ccattatgga tacgcacaga accaccgccc acttcgtaac cattgatgac
     4681 catatcgtaa gcgttagcca ccgcattttc cggtgcagct ttcagttctg ctgccgtcat
     4741 gtctttcggt gaggtgaacg gatggtgcat tgctgtcagg ccgccttcac cgtcgtcttc
     4801 aaacatcggg aagtcgataa cccacagcgg tgcccatttg ctttcgtcgg tcagaccaag
     4861 gtctttaccc actttcaggc gcagtgagcc catcgcgtcg gcaacaattt tcttgttgtc
     4921 ggcaccgaag aaaatcatat cgccatcttg cgcgccagta cgctccagga tggcttcgat
     4981 gatttctgca ttaaggaact tcgctaccgg gctgttgata ccttccagac ctttcgcgcg
     5041 ttcgttaact ttgatgtaag ccagaccttt cgcgccgtag attttaacga agttaccgta
     5101 ttcgtcgatc tgcttacggg tcaacgatgc gccgcccgga acacgcagag cggcaacacg
     5161 gcctttcgga tcgttcgccg gacctgcaaa tactgcaaac tcaacagatt tcagcagatc
     5221 ggcaacgtcg gtcagttcca tcgggttacg tagatctggt ttatcagaac cataacggcg
     5281 ttctgcttct gcaaaggtca ttaccgggaa atcgcccaga tccacgccct tcacttccag
     5341 ccacagatga cgcaccagcg cttccatcac ttcacgcact tgcggcgcgg tcatgaaaga
     5401 agtttccaca tcgatctgag taaattcagg ctgacggtca gcacgcaggt cttcgtcacg
     5461 gaagcattta acgatctgat agtagcggtc aaagccggac atcatcagca gctgtttgaa
     5521 caactgtggg gattgcggca gtgcgtagaa tttacctttg tgcacacgag aaggcaccag
     5581 gtagtcacgc gcgccttccg gcgtggcttt ggtcagcatc ggagtttcga tgtcgaggaa
     5641 gccgtggtca tccataaaac ggcgcaccag gctggtgatt ttagcgcggg ttttcaggcg
     5701 ctgagccatt tccgggcgac gcaggtcgag gtagcggtat ttcagacgcg cttcttcggt
     5761 gttgacgtgg ttagagtcaa gcggcagaac atctgcacgg ttgatgatag tcagcgagga
     5821 cgccagtact tcgatttcgc cagtcgccat atcgcggtta atattttttt cgtcacgcgc
     5881 acgtacggtg cccgtgacct gaatgcagaa ctcattacgc agttcagagg ccagctttaa
     5941 cgcgtccgca cgatccggat cgaaaaatac ctgcacgata ccttcgcggt cgcgcatatc
     6001 gatgaagatc aggctaccaa gatcacgacg acggttgacc caaccacaca gagtcacctg
     6061 ctgccccacg tgggacaaac ggagctgtcc acaatattct gtacgcatga gatatccctt
     6121 aacttagctg ccggcggatg ccccctgctg cgcaggtgac caagtcgcag cgttagctgt
     6181 atgtcacaac tgaatgaaaa aaggcggcta ttatactgga aattctgccg caccgtaaga
     6241 gcctggcccg cgctggaacg cctcgttacc actttatatc gggcctgaaa tcagactcta
     6301 cgccagtttg ctataaaggt gttgcccgaa ctcataaaaa ttaacaaaat ttgtcgttcc
     6361 gccatcggct catcgtatta aggtgagagg cacgattttg ttttatcagg agtcatcatg
     6421 cttgaactta atgctaaaac caccgcgctg gtggtgattg atttacaaga aggcatcttg
     6481 ccttttgccg gtggtccaca tactgccgat gaggtggtta atcgcgccgg gaagctggcg
     6541 gcgaaatttc gcgcgagcgg tcagcccgtg tttctggtgc gtgttggctg gtctgccgat
     6601 tatgctgaag cattaaaaca gccggttgat gccccttccc ccgctaaagt gttgcccgaa
     6661 aattggtggc aacatcctgt agcattaggt gcaaccgaca gcgatatcga aatcatcaaa
     6721 cgtcaatggg gtgcgtttta cggtacggat ctggaattgc agttgcgccg ccggggtatc
     6781 gatacaatag tgttatgtgg gatctcgacc aatatcggtg ttgaatccac cgcccgcaat
     6841 gcctgggaac tcggttttaa tctggtgatt gccgaagatg cctgtagcgc cgctagcgcc
     6901 gagcagcaca ataacagcat taatcatatc tacccgcgca tcgcccgtgt gcgtagcgtt
     6961 gaagagatcc tccacgcgtt atgatttaca tcggtttgcc acaatggtcg catcctaaat
     7021 gggtgcggtt ggggatcacc agccttgaag agtatgcccg ccactttaac tgtgtggagg
     7081 gtaacaccac gctttatgcc ctgccgaaac ccgaggttgt cctgcgctgg cgtgagcaga
     7141 ccacagatga cttccgcttc tgttttaagt ttccggcgac tatttcgcat caggcagcat
     7201 tacggcattg cgatgattta gtgactgaat ttttgacccg catgtcaccg ttggctccgc
     7261 gcattggaca atactggctg caactgcctg ccacattcgg cccacgggag ctgcctgcgc
     7321 tttggcattt tctcgattct cttcccggcg aatttaatta tggtgtggaa gtccgccatc
     7381 cacagttttt cgccaaaggg gaagaggaac aaacgcttaa tcgcggttta catcagcgcg
     7441 gcgttaatcg ggtgatttta gacagccgcc cggttcatgc agcacgtcca cacagtgaag
     7501 ctattcgcta cgctcaacga aaaaaaccta aagttccggt acatgctgta ctgacggcga
     7561 aaaatccact gatccgtttt atcggtagtg atgatatgac gcaaaaccgg gaattatttc
     7621 aggtctggtt acaaaaatta gcgcagtggc atcagaccac tacgccttat ctttttttac
     7681 atacgccaga tattgcccag gccccggaac tggtacatac cctgtgggaa gacttacgta
     7741 aaacgcttcc agagatcgga gcagttccgg ctattccaca gcaatcttct cttttctgaa
     7801 tttgccacct atcatagaca ggtgccatcg gccattttaa agggagtttg tatggtaagc
     7861 gcgctgtatg ccgttttaag tgcgttgtta ttaatgaagt tctcttttga tgtcgttcgc
     7921 ctgcgaatgc agtaccgcgt tgcctatggc gacggcggtt ttagcgaact gcaaagcgct
     7981 attcgcattc atggtaacgc ggtggaatat attcccatcg cgattgtgtt gatgctgttt
     8041 atggaaatga atggcgcaga aacctggatg gtgcatattt gcggcatcgt tttgcttgct
     8101 ggtcgtctga tgcattatta cggttttcat caccgtctgt tccgctggcg acgttctggc
     8161 atgagcgcca cctggtgtgc gctgttgctg atggtgctgg cgaatctttg gtatatgccc
     8221 tgggagttgg ttttctccct gcgttagcgc acaatacgcc actttctttt tcccggattt
     8281 ttacgttatg tctcaccgcg acacgctatt ttctgcccct atcgccagac tgggcgactg
     8341 gacctttgat gaacgggtag ctgaagtctt cccggatatg atccagcgtt ccgttcccgg
     8401 ctattccaat attatttcca tgattggtat gttagccgag cgcttcgttc aacctggtac
     8461 gcaggtttac gatctgggtt gttctctggg cgcggcgaca ctctcggtgc gtcgcaacat
     8521 tcatcatgat aattgcaaaa ttattgccat cgataactcc ccggcgatga ttgaacgctg
     8581 ccgtcgtcat attgacgcct ataaagctcc tacgccagta gacgttattg aaggtgatat
     8641 tcgcgatatc gccattgaaa acgcatcgat ggtggtgctg aattttaccc tgcaattcct
     8701 ggaaccttcc gagcgccagg cgttactgga taaaatttat caaggactga acccgggcgg
     8761 cgcgctggtg ctttcggaaa aattcagttt cgaagatgcc aaagttggtg aactgctgtt
     8821 caacatgcac cacgacttta aacgtgccaa cggttacagc gaactggaga tcagccagaa
     8881 acgcagcatg ctggaaaacg tgatgctgac cgattccgtg gaaacccata aagcacgcct
     8941 gcataaagcc ggttttgagc atagcgagct gtggttccag tgctttaact ttggttcact
     9001 ggtggcatta aaagcagagg acgctgcatg atcgactttg gtaactttta ttctctgatt
     9061 gccaaaaatc atctttcaca ctggctcgaa acgctgccca cgcagattgc taactggcag
     9121 cgcgagcagc agcacgggct gtttaagcag tggtccaacg cggtggaatt tctgcctgaa
     9181 attaaaccgt atcgtctgga tttattgcat agcgtaaccg ccgaaagcga agagccactg
     9241 agcgccgggc aaattaagcg cattgaaacg ctgatgcgca acctgatgcc gtggcgcaaa
     9301 gggccgttct cactgtatgg cgtcaacatc gataccgaat ggcgttccga ctggaaatgg
     9361 gatcgcgttc tgccccatct ttctgattta accgggcgca ccattcttga tgtcggctgc
     9421 ggcagcggtt atcacatgtg gcgcatgatt ggcgctggcg cgcacctcgc ggtggggatc
     9481 gaccctacac aactgtttct gtgccagttt gaagcggtgc gtaaactact gggtaacgat
     9541 cagcgcgcac atttgttacc gttaggtatt gaacaacttc cggcactgaa agcctttgat
     9601 accgtctttt cgatgggcgt gctttatcat cgtcgttcac cgctggagca tctctggcag
     9661 ttaaaagacc aactggtgaa tgaaggcgaa ctggtgctgg aaacgctggt tattgatggc
     9721 gatgagaaca cggtgctggt gccgggcgat cgttacgcac aaatgcgtaa tgtctatttc
     9781 attccttccg cgctggcgct gaaaaactgg ctgaagaagt gtggttttgt tgatattcgc
     9841 attgcggatg tgagcgttac caccacagaa gagcagcgac gcaccgaatg gatggtcacc
     9901 gagtctctgg ccgattttct cgacccgcat gatccgggta aaacggtgga aggttatcct
     9961 gcgcctaaac gcgcggtgct gattgcgcgc aagccgtaaa aatttagcgc ccgtttccgg
    10021 gcgcttttta cgtcttatgc ctgaatagct ggctgatcaa acgccgttaa cttcagcgca
    10081 ttgcccgtat atttttcgat atacaccagc gcagagttac cggcacaggc attcgccagc
    10141 tgcgagctgg ggatatccgc cgttaacacg ttcgcactac cgtttttaca caagccattt
    10201 tccagatctg gccatgcacc ttcatgcacg cataccacgc cttttttgat cccgtcagtc
    10261 accaccgcgc ctgtcagaat ctgaccacgt ttgttccaga cacgcaccag atcgccattc
    10321 gcaataccaa agcgagcagc atcttcggtg tgaatagtga ttggttcacg atcggcaacc
    10381 gcatattttt tacgcagttc cgcatagtta agctgactgt gtaaacggtg tgccggatgt
    10441 gcggtcagaa gctgcaactg cttctcgtcg gcggtaccct tccactcatc aggcgcaagc
    10501 caggttgggt gtgccgggca atccttatag ccaaattttt ccagcgttct ggagtaaatc
    10561 tcaattttgc cgcttggcgt acccagcgca tttttcaccg gatcggcgcg gaaatcacca
    10621 taacgaatgt actgttcgtt cttctcgctg cggcgcattt cgatcagttt attttgctgc
    10681 cagaaggcat taaacatcgg catcgtcacg cgttgcgcac gggcaccttt ctgagcggca
    10741 tcatagaaaa atttcagcca cgccatttca tctttacctt cggtatagat ctcttttccg
    10801 ccaggtttga gtaattcagc aagatcggca aacacgtcaa aatcgttgcg cgcttcaaat
    10861 tgcggagcga cagcctgctt catcggcaca atatgctggt tgctgtaatc accggtcatc
    10921 gtcaggtcat tgcgctcaaa cgatgtggtg atcggtaata cgatatctgc gtgtttggct
    10981 gctgcggtcc agtagcattc agaaacgacg atcatctccg gtttctgcca tgctttaatc
    11041 agacgattag tatcctggtg atgggtaaag ttaccgccac ccgcccacca gatcattttg
    11101 atattcggat acgtttgttc tttaccgtta tgctgatatt tgccgccagg attttccagc
    11161 gcatcgacga tacgggcaac aggaatcgcc gtcattccgc catcatcagc ggcctcgctg
    11221 gcctgtccgg caatcgccgc agacatttct ggtagcacgc cgccaacacg cgtcgggttg
    11281 ccaccgttgg agtaatgata agagaaacca aacccgccgc ccggtgtacc aatttgccct
    11341 aacatcgccg ccagcgtcac cagcatccag tgtttctgtt caccgtattg ctggcgctga
    11401 attccccagc ctgccatcag cattgtgcga tttgccgcca tcagttctgc aagtttcaca
    11461 atctgcgctt ccggcacgcc agtaatttcc gccgcccagg ccgcactctt cggcgtatta
    11521 tcgttcttgc ctgtcagata ctcttcaaac tgcggatacc cggtagtgta tttttcaagg
    11581 aacactttat cgtgtttgcc ttgtgtcatc agggtatgcg caatccctaa catcagtgcc
    11641 acgtcggtgc ccatattcgg tgcgatccag gtggcattat cgccaaagaa ttcgatggtt
    11701 tcggagcgga taggatcaat ggcaatcact ggtttgccag attttttcag ctgatggaag
    11761 tattccagcc cttgttcatc ggtactgctc caggcaattt ttaaggtatt cagcgggttc
    11821 atgccccaca acaccaccac ctgactgttt tccagaatca gcggccagga agtctgctgt
    11881 tcatagacct ccacagaacc gaccacatgc ggcatgatca cctgtgccgc tccggttgaa
    11941 taatcgccgc tatgcccgga ataaccgccc gccaggttca tataacgttg cagtaaggtt
    12001 tgcgctttat gcaacacgcc agaagaacgc cagccgtaag atccggcaaa aatggccgat
    12061 ggtccgttag ctttacgaat atgatcgtgt tgctcatgaa tcagttttaa tgcttgttcc
    12121 cagctcacct gtacataggt atcttcgcca cgacctttcg ccggttgcag tggattatcg
    12181 agatagcttt ttctcaccat cggatgctga atacgcgccg tggtgtgtac ctgatccgcc
    12241 gccgtagact gtaaggagtt cggtatggtc ttcgccagcg cgcctgtcga agaaacaatc
    12301 ttgccgtcct tcacttctac gttcatcgct ccccaacgtc ccgcggtgag aattttgccg
    12361 cccttctctt ctgcccatgc aggtaacggt gcagccgatg tcaccaccag cgccccagcg
    12421 gcaataccgc tatgtttaat aaattcgcgt cttgttaatg tcataacttc ctccctgatc
    12481 aacgaggatc actgtttctc ggtaatatct ttggcgttgt actggaagta ccgcgtcaaa
    12541 atgtccagtt cgttttcgct catgctggtt cgcgcaccca ttcctttggc aatggacggc
    12601 catgcattga cggtgtaatg gtcggcggca ataggggcat ggcagccagc gcaataggta
    12661 tcgtcaagtt tttcagcgta ttgccatagt ggtttacggt ccgctaatgc ggaatcggtt
    12721 agcgcaccct gtaaagacgc ctgacgccat tgattgccgt attcgtcagc ctgccattcc
    12781 ccgtttaccg ttagcgcctt gataccttct tcacttaatg tggcgagcgc cagccgttga
    12841 cctgccgcca ggtagagcgt gttttcactg ccctgcattt gataaccctg caaccgaaca
    12901 attggctgtt taccactgac atcaacgacg gtgagatcgg taccaggagt cacggtagcc
    12961 aggtcgccta tgcgagaagt tttgaaagga taaatatgtg cgccattagt aactgaagta
    13021 gcggcctgac tttccagctc atgcgccgcg ttgtcatcca tttttatttc tggcgggaaa
    13081 tgggcaatgc ctttatggca atcgatacaa gtttcgccgt ccttttgcgc tttattatgc
    13141 attttctgcg cagattcact ttgcgaggaa atatccatgg catcaaaaga atggcaacta
    13201 cggcaggttg cagagtcagt tgcttttaat tctttccata ctgtttcggc catttcctgg
    13261 cgatgagctt cgaacttatc gtcactgtct attttgccgc taacaaattc atgataaata
    13321 tctt
//
LOCUS       DAFGPF010000131        13176 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFGPF010000131 DAFGPF010000000
VERSION     DAFGPF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13176
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.131"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1792)
                     /locus_tag="LSX49_004289"
     CDS             complement(<1..1792)
                     /locus_tag="LSX49_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HBL7170609.1"
                     /translation="MAGIYRCILLLIVGLFFSSLSYAKNTEIPSYEEGISLFDVEATL
                     QPNGVLDIKENIHFQARNQQIKHGFYRDLPRLWMQPDGDAALLNYHIVGVTRDGISEP
                     WHLDWHIGLMSIVVGDKQRFLPQGDYHYQIHYQVKNAFLREGDSDLLIWNVTGNHWPF
                     EIYKTLFSLKLPDIAGNPFSEIDLFTGDEGDTYRNGRILEDGRIESRDPFYREDFTVL
                     YRWPHALLGNAPAPQTTNIFSHLLLPSTSSLLIWFPCLFLACGWLYLWKRRPQFTPVD
                     VIETDVIPPDYTPGMLRLDAKLVYDDKGFCADIVNLIVKGKIHLEAHYDKNQQILIRV
                     NEGATRNNAVLLPAEQLLLEALFRKGDKVVLTGRRNRVLRKAFLRMQKFYLPRKKSSF
                     YRPDAFLQWGGMAILAVILYGNLSPVGWAGMSLVGDMFIMICWLLPFLFCSLELLFAR
                     DDDKPCVNRVIITLFLPLICSGVAFYSLYINVGDVFFYWYMPAGYFSAVFLTGYLTGM
                     GYIFLPKFTQTGQQRYAHGEAIVNYLARKEAATHSGRRRKGEARKLDYALLGWAVSAN
                     LGREWAARITPSLTAAVRAPEIARSGVLFSL"
     gene            complement(1820..2440)
                     /locus_tag="LSX49_004290"
     CDS             complement(1820..2440)
                     /locus_tag="LSX49_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBL7170610.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            complement(2437..3318)
                     /gene="yciV"
                     /locus_tag="LSX49_004291"
     CDS             complement(2437..3318)
                     /gene="yciV"
                     /locus_tag="LSX49_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HBL7170611.1"
                     /translation="MSDTNYSVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQQLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLATLARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            3456..3500
                     /gene="trpL"
                     /locus_tag="LSX49_004292"
     CDS             3456..3500
                     /gene="trpL"
                     /locus_tag="LSX49_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HBL7170612.1"
                     /translation="MKAIFVLKGWWRTS"
     misc_feature    3477..3570
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            3592..5154
                     /gene="trpE"
                     /locus_tag="LSX49_004293"
     CDS             3592..5154
                     /gene="trpE"
                     /locus_tag="LSX49_004293"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HBL7170613.1"
                     /translation="MQTQKPTLELLTCVGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLALLDNALPAGVENEQSPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNELRQQ
                     LTEAAPPLPVVSVPHMRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGVATVQAGAGVVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     gene            5154..6749
                     /gene="trpD"
                     /locus_tag="LSX49_004294"
     CDS             5154..6749
                     /gene="trpD"
                     /locus_tag="LSX49_004294"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HBL7170614.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEQTNTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRCVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            6753..8111
                     /gene="trpCF"
                     /locus_tag="LSX49_004295"
     CDS             6753..8111
                     /gene="trpCF"
                     /locus_tag="LSX49_004295"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HBL7170615.1"
                     /translation="MQTVLAKIVADKAIWVEARKQQQPLASFQNEIQPSTRHFYDALQ
                     GARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFDFLPI
                     VSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV
                     LTEVSNEEELERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGIN
                     TYAQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVCGLTRGQDAKAAYDAGA
                     IYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLH
                     GNEDQLYIDTLREALPAHVAIWKALSVGETLPARDFQHIDKYVFDNGQGGSGQRFDWS
                     LLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLR
                     AY"
     gene            8123..9316
                     /gene="trpB"
                     /locus_tag="LSX49_004296"
     CDS             8123..9316
                     /gene="trpB"
                     /locus_tag="LSX49_004296"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HBL7170616.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETDVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            9316..10122
                     /gene="trpA"
                     /locus_tag="LSX49_004297"
     CDS             9316..10122
                     /gene="trpA"
                     /locus_tag="LSX49_004297"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HBL7170617.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPVGLLMY
                     ANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKAFVQPMKATTRR"
     gene            complement(10173..10313)
                     /locus_tag="LSX49_004298"
                     /pseudo
     CDS             complement(10173..10313)
                     /locus_tag="LSX49_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309783.1"
                     /note="receptor for colicin S4; incomplete; partial in the
                     middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
     gene            10498..10773
                     /locus_tag="LSX49_004299"
     CDS             10498..10773
                     /locus_tag="LSX49_004299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HBL7170618.1"
                     /translation="MTVFVLRGYIPHTTAKSVVGIGVSDNITTHSRVCGFFCVKHCHI
                     RIMVGRAGAEKSAPGFVMTGYANPVRLTTSLIGVRGGDHPINWSHHI"
     gene            10770..11327
                     /locus_tag="LSX49_004300"
     CDS             10770..11327
                     /locus_tag="LSX49_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBL7170619.1"
                     /translation="MNTAITFSNESPKVFFKDGRLVTTSQAVADYFDKQHKHVLAKID
                     TLDCSPEFTSANFSADVQTVEIGNGAERESRCYLITKDGFMFLVMGFTGKKAARLKEA
                     YIEKFNAMEEELHKRPPAAQNSPAPNNGCALLIHFDKHGQVEFTEKVPADAMVCTLER
                     FKFYLEQHGWIVARKEQLVERLMRF"
     gene            complement(11454..11624)
                     /locus_tag="LSX49_004301"
     CDS             complement(11454..11624)
                     /locus_tag="LSX49_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001710241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170620.1"
                     /translation="MVRLPPVVMSAKSATARTTIAREDAEDHQVKLSAQKLEELLASM
                     VKDEVDRNDGIY"
     gene            complement(11739..12008)
                     /locus_tag="LSX49_004302"
     CDS             complement(11739..12008)
                     /locus_tag="LSX49_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBL7170621.1"
                     /translation="MLPQHSDIEIAWYASIQQEPNGWKTVTTQFYIQEFSEYIAPLQD
                     AVDLEIATEEERSLLEAWNKYRVLLNRVDTSTAPDIEWPANPVRE"
     gene            12065..12733
                     /locus_tag="LSX49_004303"
     CDS             12065..12733
                     /locus_tag="LSX49_004303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL7170622.1"
                     /translation="MVKSMKKNTDDGAKIYTPLTLKLYDWWVLGVSNRLAWGCPTKEH
                     LLPHFLEHVGNNHLDIGVGTGFYLTHVPESSLISLMDLNEASLNAASTRAGESKIKHK
                     ISHDVFEPYPAALHGQFDSISMFYLLHCLPGNISTKSCVIRNAAQALTDDGTLYGATI
                     LGDGVVHNSFGQKLMRIYNQKGIFSNTKDSEEGLTHILSEHFENVKTKVQGTVVMFSA
                     SGKK"
     gene            complement(12788..12886)
                     /locus_tag="LSX49_004304"
                     /pseudo
     CDS             complement(12788..12886)
                     /locus_tag="LSX49_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885581.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(12932..13114)
                     /locus_tag="LSX49_004305"
     CDS             complement(12932..13114)
                     /locus_tag="LSX49_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL7170623.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALVCAGYEQIFEDKLSGTRTGRPG
                     LKRALKRLQKGDALVV"
BASE COUNT         3320 a         3389 c         3261 g         3206 t
ORIGIN      
        1 gtaatgagaa caaaacgcca ctacgggcaa tttccggggc gcggacagcc gctgtgagtg
       61 atggggtgat acgtgcagcc cattctctgc caaggtttgc cgagaccgcc caacctaaca
      121 aagcgtaatc cagtttccgt gcttcccctt tcctccgccg cccactgtgt gttgctgcct
      181 ctttacgcgc aagatagtta acgatagctt caccgtgggc ataacgttgc tgcccagttt
      241 gggtaaactt tggcagaaaa atatacccca tgccagtgag ataaccggtc aggaaaacag
      301 cgctaaaata acccgctggc atataccagt aaaagaatac atctccgaca ttgatgtaga
      361 gagaatagaa ggccacgcct gaacaaatca gtggtaaaaa caaagtgatg attacacgat
      421 taacgcaagg cttgtcatca tcgcgggcaa acaaaagctc aagggaacaa aataagaaag
      481 gaagaagcca gcagatcata ataaacatat cgcctaccag actcattcct gcccaaccta
      541 cgggactcag gttaccgtag agaatgaccg ccaatatcgc catcccgccc cattgcaaaa
      601 acgcatcagg tcggtaaaac gaagactttt tacgcggcag ataaaatttc tgcatccgta
      661 aaaatgcctt gcgtaagact ctgttgcgtc tccccgtaag aacgacctta tcgcctttac
      721 gaaataacgc ttccagtaat aactgctctg cgggcagtaa taccgcatta tttctggtcg
      781 cgccttcatt aacacgaatc aggatttgct ggttcttgtc ataatgagct tccagatgaa
      841 tttttccttt cacaatcaga tttacgatat cggcgcaaaa acctttatcg tcataaacca
      901 gcttcgcatc gagacgtaac atgccgggcg tgtaatctgg cggaatgaca tcggtttcaa
      961 tcacatctac cggcgtaaat tgcggcctgc gcttccagag atataaccat ccacacgcca
     1021 ggaacaggca cggaaaccaa attaacaacg atgacgtaga gggtaaaaga agatggctga
     1081 aaatattcgt cgtttgtggt gccggggcat taccaagtaa agcgtgaggc cagcggtaga
     1141 ggaccgtgaa atcttcacga taaaacggat cgcgagattc aattcttccg tcctcaagga
     1201 tgcggccatt tcgatatgtg tcgccctcat ctccggtaaa gagatcgatt tcgctaaatg
     1261 gattacccgc aatatcaggc aacttgagtg aaaatagggt cttatatatt tcaaacggcc
     1321 agtggttacc ggtcacgttc cagattagca gatcagaatc cccctcacgc aggaaagcat
     1381 ttttaacctg ataatgaatt tgataatgat agtcgccttg aggcaagaaa cgttgtttat
     1441 cgcccacgac aatactcatt aacccgatat gccagtcaag atgccagggt tcagaaatac
     1501 catcacgggt gacgccaaca atatgatagt tcagcagtgc agcgtcccca tcaggctgca
     1561 tccagagtcg cggtaaatca cgataaaatc cgtgcttaat ctgctgattt cgcgcctgaa
     1621 aatgaatgtt ctctttgatg tcgagcaccc cattcggttg cagagtggct tcaacatcaa
     1681 agagcgagat cccttcttca taagaaggga tctccgtgtt tttcgcataa ctcaacgaag
     1741 agaaaaaaag cccaactatc aatagcaaaa tgcagcgata tatccctgcc ataatcttcc
     1801 atccgtggaa cgcaatttgt tataagaaag gcttcacatc acctacgcct tcacgcacca
     1861 cgaccggcgt atcatcggtg agatcaataa ccgttgttgg tttctgcccg agatagccgc
     1921 cgtgaataat caaatccacc tgtttttcca gacggtcttt aatttcttcc ggatcggatt
     1981 cggtaaattc actgcctggc agcattagcg aagtggaaag catcggttcg cccaatgctt
     2041 caagcagcgc ctgcgcaatc gggttagacg gcacgcgcat accgatggtt ttgcgttttt
     2101 cctgcaacag acggcgtggc acctccttag tccccttcag gatgaaggta tagttgcctg
     2161 gcgtgttgtt tttcatcaaa cgaaacgcaa cgttatcgac aaatgaatag gtcgagagtt
     2221 cagaaagatc gcgacacatc agggtaaagt tgtgaccgtc cggcagctgg cgaatacgac
     2281 aaatacgctc catcgcgttt ttatcttcaa ttttacagcc gagcgcatag ccggaatcag
     2341 ttggataaac aatcaccccg cctttacgca cgatctccac cgcctggttg atcaggcgtt
     2401 gctgcgggtt atcaggatga atataaaaaa actggctcat aattccctct ctgtggtgtt
     2461 ctgcggctgt tcccatagct gccagacgcc ttcaacgcct gcgggcagcc agagtttacg
     2521 acccagttcg atccacgggc atggttgatg aaaatcagat ccttgtgatg cccataaatg
     2581 atgctgacgc gcaagtgtcg ccagctgggt gcgttcattg ggcgattgct ggcactgcgc
     2641 gacttccatc gcgtcgccgt ggtgttcggc aaaatgcgca accaatcttt tcagccattt
     2701 agcactaaga ttgtaccgcc ctggatgagc tagcaccgcc ttaccgccag aatgatgaat
     2761 gacatcaata gcttgttcta ttgtacacca ctgtggcgga acgtatccgg ttttcccgcg
     2821 cgccagatac tttttaaaga catccgccat tgaactggct tttccgcact ccacaaggaa
     2881 acgcgcaaaa tgaccgcgcg tcaccgcacc gccctgcgcc agttgttgcg cgccttccag
     2941 tgccccaggt atttgtgctt tttcaagtct ttcggcaatc agctgcgccc gctgattgcg
     3001 ccgttctgtc tgctgcgcga ggaactcaca cattagcgga tgagtaatat caatattcag
     3061 cccgacaata tgaatttcat gattttccca gaccgtggaa atttccacac caggaataag
     3121 attcagcgcc agtcccgaac gtgaaatttc ctctcttgct ggtgcaattg cagctgtggt
     3181 gtcatggtcg gtgatcgcca gggtgccgac gcgcatctcg actgcacggt gcaccaatgc
     3241 ttctggcgtc aggcagccat cggaagctgt ggtatggctg tgcaggtcgt aaatcactga
     3301 gtaattcgtg tcgctcaagg cgcactcccg ttctggataa tgttttttgc gccgacatca
     3361 taacggttct ggcaaatatt ctgaaatgag ctgttgacaa ttaatcatcg aactagttaa
     3421 ctagtacgca agttcacgta aaaagggtat cgacaatgaa agcaattttc gtactgaaag
     3481 gttggtggcg cacttcctga aacgggcagt gtattcacca tgcgtaaagc aatcagatac
     3541 ccagcccgcc taatgagcgg gctttttttt gaacaaaatt agagaataac aatgcaaaca
     3601 caaaaaccga ctctcgaact gctaacctgc gtaggcgctt atcgcgacaa cccaaccgcg
     3661 ctttttcacc agttgtgtgg ggatcgtccg gcaacgctgc tgctggaatc cgcagatatc
     3721 gacagcaaag atgatttaaa aagcctgcta ctggtagaca gtgcgctgcg cattacagca
     3781 ttaggtgaca ccgtcacaat ccaggcactt tccggcaatg gcgaagccct gctggcacta
     3841 ctggataacg ccctgcctgc gggtgtggaa aatgaacaat caccaaactg ccgcgtactg
     3901 cgcttcccgc ctgtcagtcc actgctggat gaagacgccc gcttatgctc cctttcggtt
     3961 tttgacgcat tccgcttatt acagaatctg ttgaatgtac cgaaggaaga acgagaagca
     4021 atgttcttcg gcggcctgtt ctcttatgac cttgtggcgg gatttgaaga tttaccgcaa
     4081 ctgtcagcgg aaaataactg ccctgatttc tgtttttatc tcgctgaaac gctgatggtg
     4141 attgaccatc agaaaaaaag cacccgtatt caggccagcc tgtttgctcc gaatgaagaa
     4201 gaaaaacaac gtctcactgc tcgccttaac gaactacgtc agcaactgac cgaagccgcg
     4261 ccgccgctgc cggtggtttc cgtgccgcat atgcgttgtg aatgtaacca gagcgatgaa
     4321 gagttcggtg gcgtagtgcg tttgttgcaa aaagcgattc gcgccggaga aattttccag
     4381 gtggtgccat ctcgccgttt ctctctgccc tgcccgtcac cgctggcggc ctattacgtg
     4441 ctgaaaaaga gtaatcccag cccgtacatg ttttttatgc aggataatga tttcaccctg
     4501 tttggcgcgt cgccggaaag ttcgctcaag tatgacgcca ccagccgcca gattgagatt
     4561 tacccgattg ccggaacacg tccacgcggt cgtcgtgccg atggttcact ggatagagac
     4621 ctcgacagcc gcatcgaact ggagatgcgt accgatcata aagagctttc tgaacatctg
     4681 atgctggtgg atctcgcccg taatgacctg gcgcgtattt gcacccccgg cagccgctac
     4741 gtcgccgatc tcaccaaagt tgaccgttac tcttacgtga tgcacctggt ctcccgcgtt
     4801 gttggtgagc tgcgccacga tctcgacgcc ctgcacgctt accgcgcctg tatgaatatg
     4861 gggacgttaa gcggtgcgcc gaaagtacgc gctatgcagt taattgccga agcagaaggt
     4921 cgtcgccgcg gcagctacgg cggcgcggta ggttatttta ccgcgcatgg cgatctcgac
     4981 acctgcattg tgatccgctc ggcgctggta gagaacggag tcgccaccgt gcaagccggt
     5041 gctggcgtgg tacttgattc tgttccgcag tcggaagccg acgaaacccg taataaagcc
     5101 cgcgctgtac tgcgcgctat tgccaccgcg catcatgcac aggagacgtt ctaatggctg
     5161 acattctgct gctcgataat atcgactctt ttacttacaa cctggcagat cagttgcgca
     5221 gcaatggtca taacgtggtg atttaccgca accatattcc ggcgcagacc ttaattgaac
     5281 gcctggcgac gatgagcaat ccggtgctga tgctttctcc tggccccggt gtgccgagcg
     5341 aagccggttg tatgccggaa ctcctcaccc gcttgcgtgg caagctgcca attattggca
     5401 tttgcctcgg acatcaggcg attgtcgaag cttacggggg ctatgtcggt caggcgggcg
     5461 aaattcttca cggtaaagcg tcgagcattg aacatgacgg tcaggcgatg tttgccggat
     5521 taacaaaccc gctgccagtg gcgcgttatc actcgctggt tggcagtaat attccggccg
     5581 gtttaaccat caacgcccat tttaatggca tggtgatggc ggtgcgccac gatgcggatc
     5641 gcgtttgtgg attccagttc catccggaat ccattcttac tacccagggc gctcgcctgc
     5701 tggaacaaac gctggcctgg gcgcagcaga aactagagca aaccaacacg ctgcaaccga
     5761 ttctggaaaa actgtatcag gcacagacgc ttagccaaca agaaagccac cagctgtttt
     5821 cagcggtggt acgtggcgag ctgaagccgg aacaactggc ggcggcgctg gtgagcatga
     5881 aaattcgcgg tgagcacccg aacgagatcg ccggggcagc aaccgcgcta ctggaaaacg
     5941 ccgcgccgtt cccgcgcccg gattatctgt ttgccgatat cgtcggtact ggcggtgacg
     6001 gcagcaacag catcaatatt tctaccgcca gtgcgtttgt cgccgcggcc tgcgggctga
     6061 aagtggcgaa acacggcaac cgttgcgtct ccagtaaatc cggctcgtcg gatctgctgg
     6121 cggcgttcgg tattaatctt gatatgaacg ccgataaatc gcgccaggcg ctggatgaat
     6181 taggcgtctg tttcctcttt gcaccgaaat atcacaccgg attccgccat gcaatgccgg
     6241 ttcgccagca actgaaaacc cgcacactgt tcaatgtgct ggggccatta attaacccgg
     6301 cgcatcctcc gctggcgtta attggtgtct acagcccgga gctggtgctg ccgattgccg
     6361 aaaccttgcg cgtgctgggg tatcaacgcg cggcagtggt gcacagcggc gggatggatg
     6421 aagtttcatt acacgcgccg acaatcgttg ccgaactgca tgacggcgaa attaagagct
     6481 atcaattgac cgctgaagat tttggcctga caccctacca ccaggagcaa ctggcaggcg
     6541 gaacaccgga agaaaaccgt gacattttaa cacgcttgtt acaaggtaaa ggcgacgccg
     6601 ctcacgaagc agccgtcgcg gcgaatgtcg ccatgttaat gcgcctgcat ggccatgaag
     6661 atctgcaagc caatgcgcaa accgttcttg aggtactgcg cagtggttcc gcttacgaca
     6721 gagtcaccgc actggcggca cgagggtaaa taatgcaaac cgttttagcg aaaatcgtcg
     6781 cagacaaggc gatttgggta gaagcccgca aacagcagca accgctggcc agttttcaga
     6841 atgagattca gccgagcacg cgacattttt atgatgcgct acagggtgca cgcacggcgt
     6901 ttattctgga gtgcaaaaaa gcgtcgccgt caaaaggcgt gatccgtgat gatttcgatc
     6961 cggcacgcat tgctgccatt tataaacatt acgcttcggc aatttcagtg ctgactgatg
     7021 agaaatattt tcaggggagc tttgatttcc tccccatcgt cagccaaatc gccccgcagc
     7081 cgattttatg taaagacttc attatcgatc cttaccagat ctatctggcg cgctattacc
     7141 aggccgatgc ctgcttatta atgctttcag tactggatga cgaacaatat cgccagcttg
     7201 cagccgtcgc ccacagtctg gagatgggtg tgctgaccga agtcagtaat gaagaggaac
     7261 tggagcgcgc cattgcattg ggggcaaagg tcgttggcat caacaaccgc gatctgcgcg
     7321 atttgtcgat tgatctcaac cgtacccgcg agcttgcacc gaaactgggg cacaacgtga
     7381 cggtaatcag cgaatccggc atcaatactt acgctcaggt gcgcgagtta agccacttcg
     7441 ctaacggctt tctgattggt tcggcgttga tggcccatga cgatttgaac gccgctgtgc
     7501 gtcgggtgtt gctgggtgag aataaagtat gtggcctgac acgtgggcaa gatgctaaag
     7561 cagcttatga cgcgggcgcg atttacggtg ggttgatttt tgttgcgaca tcaccgcgtt
     7621 gcgtcaacgt tgaacaggcg caggaagtga tggctgcggc accgttgcag tatgttggcg
     7681 tgttccgcaa tcacgatatt gccgatgtgg tggacaaagc taaggtgtta tcgctggcgg
     7741 cagtgcaact gcatggtaat gaagatcagc tgtatatcga cactctgcgt gaggctctgc
     7801 cagcacacgt cgccatctgg aaggctttaa gtgtcggtga aactcttccc gcgcgcgatt
     7861 ttcagcacat cgataaatat gtattcgaca acggtcaggg cgggagcgga caacgtttcg
     7921 actggtcact attaaatggt caatcgcttg gcaacgttct gctggcgggg ggcttaggcg
     7981 cagataactg cgtggaagcg gcacaaaccg gctgcgccgg gcttgatttt aattctgctg
     8041 tagagtcgca accgggtatc aaagacgcac gtcttttggc ctcggttttc cagacgctgc
     8101 gcgcatatta aggaaaggaa caatgacaac attacttaac ccctattttg gtgagtttgg
     8161 cggcatgtac gtgccacaaa tcctgatgcc cgctctgcgc cagctggaag aagcttttgt
     8221 cagcgcgcaa aaagatcctg aatttcaggc tcagttcaac gacctgctga aaaactatgc
     8281 cgggcgtcca accgcgctga ccaaatgcca gaacattaca gccgggacga acaccacgct
     8341 gtatctgaag cgcgaagatt tgctgcacgg cggcgcgcat aaaactaacc aggtactcgg
     8401 tcaggcttta ctggcgaagc ggatgggtaa aactgaaatt attgccgaaa ccggtgccgg
     8461 tcagcatggc gtggcgtcgg cccttgccag cgccctgctc ggcctgaaat gccgtattta
     8521 tatgggtgcc aaagacgttg aacgccagtc gcctaacgtt ttccggatgc gcttaatggg
     8581 tgcggaagtg atcccggtgc atagcggttc cgcgaccctg aaagatgcct gtaatgaggc
     8641 gctacgcgac tggtccggca gttatgaaac cgcgcactat atgctgggta ccgcagctgg
     8701 cccgcatcct tacccgacca ttgtgcgtga gtttcagcgg atgattggcg aagaaacgaa
     8761 agcgcagatt ctggaaagag aaggtcgcct gccggatgcc gttatcgcct gtgttggcgg
     8821 tggttcgaat gccatcggta tgtttgcaga tttcatcaac gaaaccgacg tcggcctgat
     8881 tggtgtggag cctggcggtc acggtatcga aactggcgag cacggcgcac cgttaaaaca
     8941 tggtcgcgtg ggcatctatt tcggtatgaa agcgccgatg atgcaaaccg aagacgggca
     9001 aattgaagag tcttactcca tttctgccgg gctggatttc ccgtccgtcg gcccgcaaca
     9061 tgcgtatctc aacagcactg gacgcgctga ttacgtgtct attaccgacg atgaagccct
     9121 ggaagccttt aaaacgcttt gcctgcatga agggatcatc ccggcgctgg aatcctccca
     9181 cgccctggcc catgcgctga aaatgatgcg cgaaaatccg gaaaaagagc agctactggt
     9241 ggttaacctt tccggtcgcg gcgataaaga catcttcacc gttcacgata ttttgaaagc
     9301 acgaggggaa atctgatgga acgctacgaa tctctgtttg cccagttgaa ggagcgcaaa
     9361 gaaggcgcat tcgttccttt cgtcaccctc ggtgatccgg gcattgagca gtcgctgaaa
     9421 attatcgata cgctaattga agccggtgct gacgcgctgg agttaggcat ccccttctcc
     9481 gacccactgg cggatggccc gacgattcaa aacgccacac tgcgtgcctt tgcggcgggt
     9541 gtgaccccgg cgcagtgctt tgagatgctg gcactgattc gtcaaaaaca tccgaccatt
     9601 cctgttggcc tgctgatgta cgccaacctg gtgtttaaca aaggcattga tgagttttac
     9661 gcccagtgcg agaaagtcgg cgtcgattcg gtgctggttg ccgatgtgcc agttgaagag
     9721 tccgcgccct tccgccaggc cgcgttgcgt cataatgtcg cacctatctt tatttgcccg
     9781 ccgaatgccg acgatgattt gctgcgccag atagcctcct acggtcgtgg atacacctat
     9841 ttattgtcac gtgcgggcgt gaccggcgca gaaaaccgcg ccgcgttacc cctcaatcat
     9901 ctggttgcga agctgaaaga gtacaacgct gcacctccat tgcagggatt tggtatttcc
     9961 gcccctgatc aggtaaaagc agcgattgat gcaggagctg cgggcgcgat ttctggttcg
    10021 gccatcgtta aaatcatcga gcaacatatt aatgagccag agaaaatgct ggcggcactg
    10081 aaagcttttg tacaaccgat gaaagccact acacgacgtt aatttgagac aaaccgccag
    10141 aaaacatctg gcggtttatt gatggtaaaa aattagaagc ggtaacctgc agagaacata
    10201 aatacccacg ggtcaaggcg tacgttgtca gaataacgcc ctgcaggcag cactgcgccg
    10261 ttggatttat atttcacttc ggtatcgata tccatgtacc agaccgacat gttttaaaaa
    10321 atgcaataag acattgtatc tgaaagaaaa aacaggattt gaggcgcttt tttataccgt
    10381 ttttccgtgt ttttaactgc ctgattttat tgaaatcttt tttagttttg cagaaaggat
    10441 tttttgctcg atcgctttaa ttttatacat tcctgataac ggaaattttt ttgcccgttg
    10501 acagtttttg ttctccgggg ctatattcct cacacaaccg caaaatcggt tgtcgggatt
    10561 ggcgtctcgg ataacatcac aacgcatagc cgcgtttgcg gttttttttg cgttaagcat
    10621 tgccacattc gcattatggt ggggcgtgca ggggcggaga aatccgcgcc gggttttgtg
    10681 atgaccggtt acgccaaccc tgtacgtctc accacctccc tgattggcgt cagaggtggt
    10741 gatcatccaa ttaattggag tcatcacata tgaatacagc tataactttt tctaacgagt
    10801 caccaaaagt ctttttcaaa gatggtcgcc tggttaccac ctctcaagct gttgccgact
    10861 acttcgataa acaacataaa cacgttttag ctaagattga cacactcgac tgctctcccg
    10921 aatttacatc agccaacttt tcggccgatg ttcagactgt cgaaattggc aacggcgcag
    10981 aacgtgaatc acgatgctac ctgatcacaa aagacggctt catgttcctc gtaatgggat
    11041 ttactggcaa aaaagcagcc agactaaaag aagcttacat tgaaaaattt aacgcaatgg
    11101 aagaagaact ccacaaacgt cctcctgcag cacaaaactc ccccgcccca aataatggat
    11161 gcgcattact gatccacttc gataaacacg gtcaggtcga gttcacagaa aaagtccccg
    11221 ccgatgcgat ggtatgcacg ctggaacggt ttaaatttta tctggagcaa catgggtgga
    11281 tcgttgcccg taaagaacaa ttggtggaaa ggttgatgcg gttttaatga atgcaaaacc
    11341 ccggatgatc accggggtta attttatcga gcgtgattgc cgctaatcgc catcgctctg
    11401 attgagcgta aatcattcag gttattcagt tcttccttct gctctcgctg acgtcaataa
    11461 atcccatcat tgcgatcaac ctcatcctta accattgatg cgagcagttc ttccagtttc
    11521 tgcgctgaca gctttacctg gtgatcttca gcatcttccc gggctattgt ggttcgcgca
    11581 gtggctgatt ttgctgacat caccacaggg ggcagacgga ccattgaacc atggcctccg
    11641 gaacaaataa gggcaaaaat aacaaccact atcgaaagct cacaaactaa ccgcagcacg
    11701 ttcctgcata cgacgtgtct gcggcataat cccaatgatt actccctgac aggatttgca
    11761 ggccactcaa tatcaggtgc agttgatgta tcaacacgat tcaacaatac ccgatattta
    11821 ttccatgcct ccagcaacga tctttcttcc tccgttgcga tttccagatc tacagcatcc
    11881 tgcagtggcg caatatactc actgaattcc tggatgtaga actgtgtggt gacggtcttc
    11941 cagccattcg gctcctgctg tatcgaagca taccaggcta tttcaatatc gctatgctgc
    12001 ggcagcattt aaccccttgt aattcatcgc cataattgat ttaattcaca aataaaacta
    12061 taacatggtg aaatcaatga aaaaaaacac agatgatggg gctaaaattt acacaccact
    12121 taccctaaag ctttatgact ggtgggtttt gggagtatca aatcggcttg catggggatg
    12181 tcctacaaag gaacaccttc ttccacactt tctggaacat gtaggtaaca accatctgga
    12241 tattggtgtt ggaactgggt tttaccttac tcacgtacct gagagtagtc tgatatcttt
    12301 aatggatttg aacgaagcta gcctgaacgc ggcatctaca agggctgggg aatcaaaaat
    12361 taaacataaa attagccatg atgtttttga accttatccc gcggcgttac atggtcaatt
    12421 tgattccatt tccatgtttt accttcttca ctgcctgcct ggaaatatat ctacaaaaag
    12481 ctgtgtaata cgcaatgcgg cgcaggcctt aactgacgat ggaactctat acggagccac
    12541 aattcttggc gatggagttg tgcacaatag cttcggtcaa aaactgatgc gcatttacaa
    12601 tcagaaaggc atcttttcaa acacaaaaga ttccgaagaa ggcttaacac atatactctc
    12661 agagcatttc gagaatgtta aaaccaaggt tcaaggtact gtagtaatgt tttccgcttc
    12721 agggaaaaaa tagcatccaa ccgcagcacg ttcttgctta agacgtgctg cggcataatc
    12781 ccaatgatta ctccctgaca gggttcgtag gccactcaat atcaggtgca gttgatgtat
    12841 caacacggtt cagtaacacc cgatactttt tctaggcttc caccaccagc acgacaagat
    12901 gccgcataca gtgaaccagt cagtccagtt ttcagacaac cagtgcgtca cctttttgaa
    12961 ggcgctttaa agcacgtttt aatccaggtc ggcctgtcct tgttccgctt aatttatctt
    13021 caaatatttg ttcatatcct gcacaaacaa gagcgtttcg ttgcagatct gtattctggt
    13081 catttgttga tacccttaca tagccaatca gcacgctgaa tctcccgtcc aaaagcacaa
    13141 atcatgccat gcaggccaga aaccgccatt atctaa
//
LOCUS       DAFGPF010000132        13130 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFGPF010000132 DAFGPF010000000
VERSION     DAFGPF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13130
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.132"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            5..791
                     /locus_tag="LSX49_004306"
                     /pseudo
     CDS             5..791
                     /locus_tag="LSX49_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313311.3"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
     gene            complement(932..1705)
                     /gene="uxuR"
                     /locus_tag="LSX49_004307"
     CDS             complement(932..1705)
                     /gene="uxuR"
                     /locus_tag="LSX49_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HBL7170624.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNTDSPDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(1920..3380)
                     /locus_tag="LSX49_004308"
     CDS             complement(1920..3380)
                     /locus_tag="LSX49_004308"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HBL7170625.1"
                     /translation="MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPDYRKAAFALMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL"
     gene            complement(3461..4645)
                     /gene="uxuA"
                     /locus_tag="LSX49_004309"
     CDS             complement(3461..4645)
                     /gene="uxuA"
                     /locus_tag="LSX49_004309"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL7170626.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAE
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            4985..6328
                     /gene="gntP"
                     /locus_tag="LSX49_004310"
     CDS             4985..6328
                     /gene="gntP"
                     /locus_tag="LSX49_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HBL7170627.1"
                     /translation="MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(6502..7404)
                     /gene="fimH"
                     /locus_tag="LSX49_004311"
     CDS             complement(6502..7404)
                     /gene="fimH"
                     /locus_tag="LSX49_004311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria D-mannose specific adhesin FimH"
                     /protein_id="HBL7170628.1"
                     /translation="MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVN
                     LAPAVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSS
                     YPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNS
                     DDFQFVWNIYANNDVVVPTGGCDVSAHDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYL
                     SGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTAN
                     YARTGGQVTAGNVQSIIGVTFVYQ"
     gene            complement(7424..7927)
                     /gene="fimG"
                     /locus_tag="LSX49_004312"
     CDS             complement(7424..7927)
                     /gene="fimG"
                     /locus_tag="LSX49_004312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimG"
                     /protein_id="HBL7170629.1"
                     /translation="MKWRKRGYLLAAILALASATIQAADVTITVNGKVVAKPCTVSTT
                     NATFDLGDLYSFSLMSAGAASAWHDVALELTNCPVGTSRVTASFSGAADSTGYYKNQG
                     TAQNIQLELQDDSGNTLNTGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQAVI
                     SITYTYS"
     gene            complement(7940..8470)
                     /gene="fimF"
                     /locus_tag="LSX49_004313"
     CDS             complement(7940..8470)
                     /gene="fimF"
                     /locus_tag="LSX49_004313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimF"
                     /protein_id="HBL7170630.1"
                     /translation="MRNKPFYLLCAFLWLAVSRVLAADSTITIRGYVRDNGCSVAAES
                     TNFTVDLMENAAKQFNDIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLA
                     LENTVSAASGLGIQLLNEQQNQIPLNAPSSALSWTTLTPGKPNTLNFYARLMATQVPV
                     TAGHINATATFTLEYQ"
     gene            complement(8480..11116)
                     /gene="fimD"
                     /locus_tag="LSX49_004314"
     CDS             complement(8480..11116)
                     /gene="fimD"
                     /locus_tag="LSX49_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher FimD"
                     /protein_id="HBL7170631.1"
                     /translation="MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSS
                     AELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSE
                     QGIVPCLTRAQLASMGLNMASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTI
                     PQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIG
                     AWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGI
                     NFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIND
                     IYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEK
                     PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD
                     DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV
                     IQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRSSTLYLSGSHQTYWGTSNVDEQFQAGL
                     NTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMS
                     HDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI
                     GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTD
                     WRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL
                     LMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCI
                     ANYQLPPESQQQLLTQLSAECR"
     gene            complement(11183..11908)
                     /gene="fimC"
                     /locus_tag="LSX49_004315"
     CDS             complement(11183..11908)
                     /gene="fimC"
                     /locus_tag="LSX49_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418736.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HBL7170632.1"
                     /translation="MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATR
                     VIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLR
                     ILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPP
                     DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAG
                     SNITYRTINDYGALTPKMTGVME"
     gene            complement(11945..12484)
                     /locus_tag="LSX49_004316"
     CDS             complement(11945..12484)
                     /locus_tag="LSX49_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418735.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7170633.1"
                     /translation="MKRKRLFLLASLLPMFALAGNKWNTTLPGGNMQFQGVIIAETCR
                     IEAGDKQMTVNMGQISSNRFHAVGEDSAPVPFVIHLRECSTVVSERVGVAFHGVADGK
                     NPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATG
                     RRVTGGIANAQAWFSLTYQ"
     gene            complement(12549..13097)
                     /gene="fimA"
                     /locus_tag="LSX49_004317"
     CDS             complement(12549..13097)
                     /gene="fimA"
                     /locus_tag="LSX49_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HBL7170634.1"
                     /translation="MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAAC
                     AVDAGSVDQTVQLGQVRTASLKQAGATSSAVGFNIQLNDCDTTVATKAAVAFLGTAID
                     ATHTDVLALQSSAAGSATNVGVQILDRTGAALALDGATFSSETTLNNGTNTIPFQARY
                     FATGAATPGAANADATFKVQYQ"
BASE COUNT         3178 a         3414 c         3177 g         3361 t
ORIGIN      
        1 tattatgtct atgccattaa gcaatgccct tcagagttaa attattacag ataatcactt
       61 ccttcatcat ccaaaagtcg acagtgagtt aacacgtaaa catgaacgtg cacgcatgga
      121 tacggaaaat atctatcttc cgcctcttgc tcgtggcaat aaccataatt acgatggaaa
      181 aagcgttgtc gaaattagaa aacttgatat tagtaaagag tcctggccat ttaattatgt
      241 gacagaaaca tgcagagaat tcaatggtat tacaacaaca ggacgtatgc tctatcgaaa
      301 cttgaaaatc acctcagctt tagacgaaat atatggtggt atatgtaaaa aggcgcatgc
      361 tgccacagag ttagcaaaag gattacggct aaatttattt atgaaaggcc ctttcgatcc
      421 tgttgaggac tatacagttc atgaaataac attaggccct ggttgcaatg ttcctggtta
      481 tgccggaacc acgataggat atatttcaac ccttccagct tctcaggcaa aaagatggac
      541 caatgagcag ccaaggattg atatctatat tgatcagata atgacggtaa caggggtagc
      601 aaattcttcc ggattcgccc ttgccgcatt acttaatgct aatattgagt tgggtaatga
      661 cccaataatt ggtatagaag cctatcccgg gtgatgaaaa tgcaccactc aaacgtatga
      721 ctctgcaacc gtcatctctt ccagaactgt ttgaattaaa aaatggtgaa tggaattata
      781 ttggtaaata actaccagga agaatgagta ctaacattca ggttatacag atagctaaac
      841 aatcccctgc aatttacaaa gtaatactca ttgcgacttc ttaatttaag aaagcgcaag
      901 gaacgtttac ccttgcgctt attataataa gtcaggcgtc gactttatcc agcggccatg
      961 aatcaaacag atagccatca aaataaatat cgtcaacgtt cgagaattcc agcagacgtt
     1021 gcttaacgtt ttccagatgc tgccacattg ccagcttcgc cgctcgggca tcttttttga
     1081 ttaacgcggc gaggatctgt ttgtgatcgc ccaaccactc tttgcgatac aggctgtcat
     1141 ccagatggct gtgcaactgg atccacattg gattgttttc ccgccactgc caggactgac
     1201 ggaacagctc caccagcatg ctgttatgcg ttgcttcggc aatagcgaga tggaactgca
     1261 tgtcaccgct ttcgctgctg cccggcgcac tggaagccag ttcacgctct tccagttgca
     1321 atgcctgacg cattttgacg atatcttcgc gggtagcctg cagggcggca aactcggcga
     1381 tgttgctctc aagaagctgt cgcgcctgca acagctcaaa aggacccgca tcattgcaaa
     1441 cgttggcatc cggactgtct gtgttgtggc tgcctgagct atcaagaaca tagataccgg
     1501 caccccggcg cacttccacc agccctttga tctccagcat gatcagcgct tcacgtacca
     1561 ccgtccgcgt gacatcaagc atttctgcaa tttcacgctc cggcggcaac cgttcgccag
     1621 gattgtacgg cgtctttatg atcagatcgc ggatcatcgc cccgacttcc tggtaaggtc
     1681 tttgcgcaga ggtggcagat ttcatggtgt tgtgtccgtt aggtgcggtt aatcaaattt
     1741 ttgccggatg cggcgtgaac gccttatccg gcctacaacg ggcaatttta cggcacccgt
     1801 taatctcaaa ctataccatt agcactggaa gttggcacgt acaggtgggc aaaaaaacga
     1861 aaactggtca accaaatatc agtttgattg accagtaagt ctgtagggta atcagttagt
     1921 tacagcgcag ccacacactc gcgcgcaccg cgttcgcaca gctgctgata tgccgccgtc
     1981 accgcgccaa caaagtcggc attctgcggc agatcatcgg caaaaatacc gctcaggccc
     2041 agcagcgctt tcacgcggtc tgcgccctga tactgcgcgt taatcttctg gaactcggcc
     2101 agcatcgggt cgaccacgtc aatggcatta ccctgctcat ccacgccctg ggtgtaacgc
     2161 atccagccag ccacgcccag cgccaggtga cgccagctgc cgccgttttg caggtgcaga
     2221 cgcaccggat ccagcagacg ctgcggtaac ttctggctgc cgtccatcgc aatctgccag
     2281 gtacggtgac gcagagacgg gttgctgaaa cgctcgatca gcagcgtcgc ataggcgttc
     2341 aggtccgtac cttccggcat cgacagcgtt ggcgcttgtt cctgcatcat cagggcaaag
     2401 gccgctttgc gataatccgg gttagtcatg gtgtcggcaa tagtttcata gccgccgagg
     2461 taaccgaggt atgccaggaa agagtggctg ccgttcagca tacgcagctt catcatttcg
     2521 aacggcacaa cgtctgcaac gaactgtgcg cctactttat cccagtccgg acgaccatta
     2581 acgaagttat cttcaatcac ccactgacgg aacggttcgc aggcaatggc gcacgggtca
     2641 taaacaccca gttggtcagc aatttcctgt aaggtttctg gcgtcgccgc cggaacgatg
     2701 cggtcaacca tggtgcacgg gaaggtgacg ttctcttcaa tccatgccgc cagctgcggg
     2761 tcacgcgcct gagccagccc cagtaccgcg accttcgcca catgaccgtt ttcacgcacg
     2821 ttatcgcagg acatcaccgt aaacgctttc agcccttttt cacgacgcag acgcagggct
     2881 tcgacgatgt aaccaatcgc ggacttcggc gcagtcgggt tttccagatc gtgcttgatc
     2941 agcgggttat tgagatccag ttgaccgctt gccgcatcag cgcagtagcc tttttccgtg
     3001 accgtcagag agacaatcgc cgtttgcgga cgcgccatcg cgttgagaat accttcgcag
     3061 ccgtcgattt ccgggtgcag cgcttctttc atcgaaccga taattttcag ctcggtgctt
     3121 tccgcgcctt tttccgccac ggtgtacagc agttgctgtt ttttcaggtt ttcgatcagc
     3181 acgcggtcgt tgcctggcat caggttaact tcgcagatac cccagtcgct gtcggtgctt
     3241 tccagcagat gatgggtgta cagcgcctgg tgcgcacggt gaaacgcccc gcaaccgaga
     3301 tgcacaatgc gtgattccag acgagaatga tcccatgacg ggcgggcaac cggcagattg
     3361 ctgtcaacaa tagtagtcat cgtaaactcc agaatccgtc ttcagagagt gacggcaagg
     3421 aagaaggaac cggcacggcg cgcagccatg ccggtggata ttaacggcta aagaaagcgc
     3481 gctggatcgc cagttcgaca ccgcgaactt cggccaggcc tttcagacga ccaattgcgg
     3541 agtaacctgg gttggttttc ttcttcaggt cgtccagcat ctgatgaccg tggtccggac
     3601 gcatcgggat caggtcttct ttgccttccg ctttacgacg gtgttcttct tcaacaatcg
     3661 ctttcaccac ttcgtacata tcaacgtcac cgttcaggtg cgccgcttcg tggaaggttt
     3721 tcgggttatc ttcacgcatg gtggagcgca gatgggtgaa gtaaatacgc ggaccgaact
     3781 gcttgatcat atcaaccaga tcgttgtcag cacgcacgcc gtaggaaccg gtgcacatgg
     3841 tgaaaccgtt cgccatgcta tttacggtat caaccatcca ctgcatatct tcaatggtag
     3901 aaacaatgcg cggcaggccg aggattgggc gcggcggatc gtccgggtga acagccatac
     3961 gcacgccaac ttcttcggca accggaataa tcgccttcag gaagacggca aagttttcgc
     4021 gcagtttggc tttgtcgata tctttgtaca gctccaggtg cttacggaac tggtcgaggg
     4081 tgtacccttc ttccgcgccc ggcagaccgg caatgatgtt acgggtcaga cgcgctttgt
     4141 cttcgtcgct catagtggcg aagcgttcag ctgcctgagc aatttcttct tcggtgtaat
     4201 ccgcttccgc acctgggcgt ttcaggatat gcatttcgaa tgcagcgaat tcgatctggt
     4261 cgaagcgcag agctttggag ccgtctggca gcacgtattc gaggtcagta cgggtccagt
     4321 cgagcaccgg catgaagttg tagcacacgg tgcgaatacc gcactgcgcc aggttgcgca
     4381 gagtctgctg atagttagcg atccactgct catagttgcc agtgtgggtt ttgatatctt
     4441 cgtgaattgg cacgctttct acgacagacc acaccaggcc tgcatcttca acgatagcct
     4501 tgcgtttgag gatctcttca acggaccata cttcgccgtt cgggatatgg tgcagcgcgg
     4561 taaccacgcc agttgcgccc gcctgacgga catcagctaa agaaaccgga tcgtttgggc
     4621 cgtaccagcg ccaggtctgt tccatgattt ttcctctttc acatagtggg ttccacagca
     4681 aagagacgcg gaaccctgga gttgtttagg tatccggatg aacaaccaga ccgcagccgt
     4741 ggcgttgcat cggatgagat ggcgtataag ttctaccttt tggtaataca tgtcaacccg
     4801 aattctaaaa ttggttaacc acatcacaag aatttcactc tcctggttgt tgctgcaaat
     4861 tgcagcaaag ggtaatcgat ggttattgat cagaggatgt gacattcatc gcaacaatgg
     4921 ttgaccaatt tacataacat gtcgcccaaa ataacaacgg ttcaaccagg taaggtaaaa
     4981 cgttatgcat gtgcttaaca ttctctgggt ggtattcggc attggtctga tgctggtact
     5041 gaatttgaag ttcaaaatca attcaatggt ggctttgttg gtggcggcgc tgtccgtcgg
     5101 gatgctggcg ggcatggatt tgatgtcgct gctgcacacc atgaaagcgg gcttcggcaa
     5161 cacgctgggg gaactggcta tcatcgtggt gttcggtgcg gtcatcggta aattgatggt
     5221 cgactccggc gcggctcacc agatagcaca tacgctgctg gcgcgtctcg gtctgcgcta
     5281 tgtacagctg tcggtgatta tcatcggcct gatttttggt ctggcgatgt tctatgaagt
     5341 ggcctttatc atgttagcgc cgctggttat tgtcattgcc gccgaagcta aaattccgtt
     5401 cctgaaactg gcgatcccgg cagtagcagc tgccactacc gcacattcac tgttcccacc
     5461 gcagccgggt cctgtggcgc tggtgaatgc ttatggcgca gatatgggga tggtttatat
     5521 ctatggcgta ctggtgacga tcccaagtgt aatctgcgca ggtctgatcc tgccgaagtt
     5581 cctcggcaat cttgagcgcc caacgccatc attcctgaaa gcagatcaac cggtagatat
     5641 gaacaatctg ccctctttcg gcgtttcgat tctggtgccg ctgatcccgg cgatcattat
     5701 gatctctacc accatcgcca atatctggct ggtaaaagat acccctgcct gggaagtggt
     5761 taactttatc ggttcctcgc cgattgcaat gtttattgcg atggtggttg cattcgtact
     5821 ctttggcacc gcacgtggtc atgacatgca gtgggtgatg aacgcttttg aaagtgcggt
     5881 gaaaagcatt gcaatggtga ttctgatcat cggtgcgggt ggcgtgttga agcaaactat
     5941 catcgacacc ggcattggcg acaccatcgg catgttgatg tcccacggca atatctcgcc
     6001 ctacattatg gcatggctga tcactgtgct aattcgtctg gcgacgggtc agggtgtcgt
     6061 ttcggcgatg accgccgccg ggattatcag tgctgcaatc cttgatccag caactggtca
     6121 gctggttggc gtgaatccgg cgctgctggt actggcgacg gctgcgggtt ccaacaccct
     6181 cacccacatt aacgatgcat ctttctggtt gttcaaaggt tactttgacc tgtcagtaaa
     6241 agacacgttg aaaacctggg gtctgctgga gctggtcaac tccgtggttg ggctgattat
     6301 tgtgttgatt atcagcatgg tagcgtaaaa gagcacctga gcctgccatt ggcaggctct
     6361 gttcggattg tcggcaaagt gcactttgtt tatgccagat gcgacgctgg cgcgtcttat
     6421 ctggcctaca aagggctaac gtgcagtttt ttagcttcag gcaatattgc gtacctgcat
     6481 tagcaatgtt ctgtgatttc tttattgata aacaaaagtc acgccaataa tcgattgcac
     6541 attccctgca gtcacctgcc ctccggtacg tgcgtaattt gccgttaatc ccagacttac
     6601 cgccgaagtc cctactgctc ctaacgatac cgtgttattc gctggaataa tcgtaccgtt
     6661 gcgcgtcaac tgtacgccga cgccctgcgc tggtgaaaac gacgcggtat tggtgaaaat
     6721 cgagttgccc gcatctgcgg ttgtgccgga gaggtaatac cccaggtttt ggcttttcgc
     6781 acaataaacg gtaagaggaa ttggcactga accagggtag tccggcagag taacggtgac
     6841 atcatgagca gaaacatcgc agccgccagt aggcaccacc acatcattat tggcgtaaat
     6901 attccacaca aactggaaat catcgctgtt atagttgttg gtctgtcgca aaataagcac
     6961 ggcaattaat gagccagctt taatcgccac cccacccgca ctgctcacag gcgtcaaata
     7021 aagcgccacc ggccacggct tatccgttct cgaattataa acaacccgcg gcgtttcgct
     7081 ggtagtcgga aatggatagc tactgccact atattttacg gtcccggaaa aattagataa
     7141 cacgccgcca taagccgagc ctcgttgcag tgtgacatag tctgtaatgg tttccggata
     7201 atcgttatgg caaaagattt gcgtcgaaag atctacgacc aggttttgcc ccacattcac
     7261 ggcaggcgca aggtttacat aaacattagc gctgccaccg ccaataggaa tagcggtacc
     7321 attggcggtt ttacaggcga atgaccaggc atttaccgac cagcccatca gcagtacagc
     7381 aaacagggta ataactcgtt tcatgacaat tatctcttcg ggttcagctg taggtatagg
     7441 tgatgctaat cactgcctga atggttccct gagtggctcc gccatttacc gtcaatgctc
     7501 tgacctgtaa cgggaagtgc gctgattgtg aggaatcatc cacctgaact gttttggttg
     7561 cgccagtatt caatgtgttg ccactgtcat cctgtagctc taactggatg ttttgcgcgg
     7621 tcccctggtt tttataatat ccggtactgt cggctgcccc gctgaagctg gcagtgaccc
     7681 tcgacgttcc caccggacaa ttagtcaact caagcgcaac atcatgccag gccgatgccg
     7741 ccccggcaga catcagactg aaagaataaa gatcgccgag atcaaacgtg gcattggtgg
     7801 tggaaaccgt gcacggtttg gcgacgacct taccgttcac cgtgatggtg acatcggctg
     7861 cctgtatcgt cgcacttgcg agcgccaata ttgccgccaa taaataccca cgtttgcgcc
     7921 atttcatgag catctccagt tactgatatt caagagtgaa ggtagccgtg gcattgatat
     7981 gccccgcagt gacaggcacc tgtgtcgcca ttagccgggc gtaaaaattc agcgtatttg
     8041 gtttacccgg cgtcagggtc gtccacgaaa gcgcggacga tggagcatta aggggtattt
     8101 gattttgctg ctcattcaga agctgtattc ccagtcccga agccgctgac accgtatttt
     8161 caagtgcaag caggttggca ttgtggctat ctgcaacacc ggtaaaccca acttttacgg
     8221 cagaaacggc attaccacag ggtgacagca aaatacgaaa tggaacgaca ggagtcgtcg
     8281 cgccaatgtc gttaaattgc ttcgccgcgt tttccatcaa atcaacagta aaattggttg
     8341 attcagcggc cacactacag ccgttatctc tgacatagcc gcggatagta atcgtgctat
     8401 ccgcagccaa aacgcgactt accgccagcc acaaaaaagc gcacagaaga taaaaaggtt
     8461 tgtttctcat cacgccccct taacgacatt cagctgatag ctgggttaat aactgctgct
     8521 gactctctgg tggcagttga taattggcga tacagtgagc attttcctct tctccccatt
     8581 tcacctgaac ttttcccgct aaaggcattc cgctgaggta aacctgacca ttatccgcaa
     8641 caatgccgct actctggcta ctctctgatg tcaccatcgc cccaaacggc agcggcttat
     8701 tattgtgggt tagcgtcatg agcagtttta tcccaacgcg cgctttaaac tctgctcgca
     8761 cgatcgcccc acgagtggga acaacgttag cgaccgcgtt atctaaatcg acgttatcag
     8821 ccagggtatt ggtatccagc gccactctgt tttcccgata ttcggtggca taaggcagca
     8881 cggcataacc gcgccagtcg gtacgcaccc ccgtctggtt ttcgactttt gcatcttttg
     8941 cgccaggcgc tttaacaagt accaccgtat cgtttaacgg ctgccccagc gttacgccat
     9001 tggcatgagc cagtacccca ccgctgactc cgtaatagag ctgcttaata tcatcgctat
     9061 ggctgtaacc gatattggca ttgccgtaac caccgcgata attcagcgtg gcgtagcctg
     9121 tacttccgct atttccatcg cctcccccgg catagccggt ttgcacgcta tagctgaggt
     9181 tgttgtcttc cagcaacgta ccgtatacac cagccagatt ggtcatccga ccgttgagat
     9241 cgtgtgacat gctgtagctg gcactggcat gtcgccactg agatttactg tcagaacgca
     9301 gccagtggct gaaaggaata ttgacgttaa gcgctaacat ctgatcccgt cctttttgcc
     9361 aggcgttttt cgtcaggcta tagctgagcg tccagttgat atcttcgaac gcagtattta
     9421 atccagcctg gaattgctca tcgacattac tcgttcccca ataagtttga tggctaccac
     9481 tcaaatacag tgttgatgag cgcccgagtt gctgagtaac ggtgagttgt aatttcccgc
     9541 gtttgttata agcgaggttg taatagtcgg tgaatttcgg cttaacctga ataacaccat
     9601 cctgtgtttc gatgttgtag ccattcattc gactgtatgt tgtatcagcg aaattaaaat
     9661 atccgctggt cgaataacgg taacccacta actgaatatt cgtgcctgac tcattgagcg
     9721 atttgttata gagaaaacgc accgattgtc cgtcatgctg actgtcatcg ggaagtgtgg
     9781 aattagcctg cgtcatatcc acagacagag cacccagcgc ccccatgttt ttcccgatac
     9841 cgaaattaaa agcacgataa cgatccgcca gttgcgttcc accatatatt gtccagccag
     9901 ccggaaggcc gtggagtaat gtactctgga aaaagcgggg tttttcctgt tgcgcatttc
     9961 cactacggta ttctcctgcc gtaatggaat aacgagtatg cccttcacgt tgcaaaagcg
    10021 ggactgacga atagggtacg gtaaaaatct gcgtgctgcc gtcagcctct ttgatcgtta
    10081 cctgcaagtc accactatta cctgcggcat agatatcgtt gatggtaaaa ggccccggtg
    10141 gcaccgtact attataaatg tcatacccat tttgtttaat agtgacctgt gcagtaccac
    10201 gagcaatacc gtggatcacc ggggcaaatc ctctttgact atcgggtaac atattgtcat
    10261 ctgaggccaa ttgtgcgccg cgaaagttaa taccatcgaa aatatcgccc tgagtataac
    10321 catcacccag cgtcagccgg gaacgtaacg gtattatgtc tcgctcaagc caggtattga
    10381 tatgctgcca tttatttttg ctacctgatg atctgtcgct actgttataa ctccaggtgg
    10441 tattgtcgcg taaacgccac gcaccaatat ttaacccact ctgtaggttt aaatatgcat
    10501 aatggctgtt acccccaatc cgattctgta cactatttcc gctgaaatta taattgagca
    10561 atccggcatt aataccggga tcccataact caggaggaat ataaccacgc gcgcgattac
    10621 tcataaatgc ctgagggatc gtcaggttga gtcgctgctg accaacatct aaatgcgcag
    10681 tagcgtcctg gaccattgtg gttaatggca cacaggcatc atccgccagc agattcatac
    10741 cggcgacaga agccatattc agccccatac tggcgagttg cgcgcgtgtc aggcagggaa
    10801 caatcccttg ttcactgtcg cccgtattaa atgtgacatc acgcgttgcc atataaccat
    10861 tattcaaata gatatcgacg cgatacgtcc ctggcggtaa ttcttgtcca ttttcaaaac
    10921 gcgataaatc agccacagcc tggggatcat ccgctaaaaa gcgcgggtta aaatagagtt
    10981 cggcagatga caaaggtgcc tgtgcggcaa aagcacaggc aacaaagagc cggacaaaaa
    11041 aaccagccaa acgatgctta cgaatatgca agcattgtgt gtttcgctgg taaagtctta
    11101 aattcagata tgacattatt cctccggttt aaaatcaccc ggcagtcaat tctttttatt
    11161 caggcgaaaa attccccctg cgttattcca ttacgcccgt cattttgggg gtaagtgcgc
    11221 cataatcatt tattgttcgg taagtaatat tgcttcctgc atcagaaggc aatttaaccg
    11281 tgctttcgcc cattggaggc accaatgcat tttcaagaac ccgggttccg gcattcaact
    11341 ctgttaccgt caggtaatag ggtgtcgggt taatcagcgt cagagaattc gcgctacgac
    11401 gaaatcttaa tttttctgcg gcctgatcgg gtggcaacgc taatttagcc ggacgatagt
    11461 acagtttaat gcggctgata attgcgagct gtagcgtatt ctcagtcaat tttgatttat
    11521 ccattgacgg aatcgcttta acgttcatcc agaataaact ttcccggtcc tgtggcaatt
    11581 ggttatttgt tgcatcaaga atacgcaagg tattctcttt ttttcccttc atcgcaaaca
    11641 gaggaggcgt cacgataaaa cgaccatcct ttacaccatc ggcattttcc acccatgatt
    11701 gaattaaata ggtgctattt tcatcattat ttgtcacggc aagttgcact tgtttttgcc
    11761 ctgccggata aattacgcga gtcgcaccta aggccactcc cgcttcagcg cgtccggcaa
    11821 ccatcattgc catgaacatc aggatacctg ccagcaagca gaatgttatt tcctgcgatt
    11881 tccttacatt gacgttttta ttactcactg tcctgttcct gttatcacat tatctgctga
    11941 acaattactg ataggttaaa gagaaccagg cctgtgcatt ggcgatgccg ccagtaaccc
    12001 gacgcccggt agcacgatat ttggcgatga aatgtagcga agtagagcct gagtaaagcc
    12061 gtttccagtt tgctggagga cgattaatcg gtacgaggtt tccttcatca tcaaacaacg
    12121 ctacgccaat attggtggct atccctggcc cctctcccac ggaaagcaca tccggatttt
    12181 taccatccgc gacaccgtga aacgccacac ccacacgttc actcaccacc gtgctacatt
    12241 cccgtaaatg aataacaaaa ggcaccggtg cgctatcttc ccctaccgcg tgaaaccggt
    12301 tactgctgat ttgccccata ttgaccgtca tttgtttatc accagcttca atccggcaag
    12361 tttccgcaat aatgacgccc tgaaattgca tatttccgcc gggcagcgtg gtattccatt
    12421 tatttccggc cagagcaaac attggcagca acgacgctaa tagaaataat ctcttccttt
    12481 tcatcgttat ttttatcaca caagggtggg catccctgcc cgtaatgacg tccctgaacc
    12541 tgggtaggtt attgatactg aaccttgaag gtcgcatccg cattagcagc acccggggtt
    12601 gcggcaccgg ttgcaaaata acgcgcctgg aacggaatgg tgttggttcc gttattcagg
    12661 gttgtttctg aactaaatgt cgcaccgtcc agcgccagcg cagcacccgt tctgtccagg
    12721 atctgcacac caacgtttgt tgcgctaccc gcagctgaac tctgcagagc cagtacatca
    12781 gtatgcgtag catcaattgc cgtacctaag aaggcaacag cggcttttgt ggcaacagtg
    12841 gtatcgcaat cattcagctg aatgttaaaa ccaacggcag agctggttgc tccagcctgc
    12901 ttcaggctag cggtacgaac ctggcctaac tgaacggttt gatcaacaga gcctgcatca
    12961 actgcgcaag cggcgttaac aacttcccct ttaaagtgaa cggtcccacc atttaccgtc
    13021 gtagtatcgg ccagagccgc tgcggaactg agggacagag ccgacagaac aacgattgcc
    13081 agagttttaa ttttcatgct gctttccttt aaaaaactat ttctaaatcg
//
LOCUS       DAFGPF010000133        13025 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFGPF010000133 DAFGPF010000000
VERSION     DAFGPF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13025
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.133"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            21..1673
                     /gene="hcp"
                     /locus_tag="LSX49_004318"
                     /gene_synonym="priS"
     CDS             21..1673
                     /gene="hcp"
                     /locus_tag="LSX49_004318"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBL7170635.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIIGYAREAIALREALKAQC
                     LAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            1685..2653
                     /gene="hcr"
                     /locus_tag="LSX49_004319"
     CDS             1685..2653
                     /gene="hcr"
                     /locus_tag="LSX49_004319"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HBL7170636.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSRWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVQVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKTLG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVISGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVFA"
     gene            2786..4504
                     /gene="poxB"
                     /locus_tag="LSX49_004320"
     CDS             2786..4504
                     /gene="poxB"
                     /locus_tag="LSX49_004320"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HBL7170637.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATTHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRVFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKTERKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
                     LPVKIIVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEID
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            4541..5542
                     /gene="ltaE"
                     /locus_tag="LSX49_004321"
     CDS             4541..5542
                     /gene="ltaE"
                     /locus_tag="LSX49_004321"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBL7170638.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQLAEVAAHWRAFLAR"
     gene            5553..6983
                     /locus_tag="LSX49_004322"
     CDS             5553..6983
                     /locus_tag="LSX49_004322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HBL7170639.1"
                     /translation="MPQRILVLGASGYIGQHLVHTLSQQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLNWPDNLPVLLQNIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQVIFLSSLQAPPHEQSDHLRARQATADILREAGVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPACEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLLPIPLPTRWISVWFLNVITSVPPTTARALIQGLKHDLLADDTAL
                     RALIPQPLIAFDDAVRSTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKT
                     SASLQALWRVVNQIGGKERYFFGNILWQTRALMDLAIGHKLAKGRPEREYLQTGDAVD
                     SWKVIVVEPEKQLTLLFGMKAPGLGRLCFTLEDKGDYRTIDVRAFWHPHGMPGLFYWL
                     LMIPAHLFIFRGMAKRIARLAEQSTD"
     gene            7082..8095
                     /locus_tag="LSX49_004323"
     CDS             7082..8095
                     /locus_tag="LSX49_004323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL7170640.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVLTLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(8092..8922)
                     /gene="amiD"
                     /locus_tag="LSX49_004324"
     CDS             complement(8092..8922)
                     /gene="amiD"
                     /locus_tag="LSX49_004324"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiD"
                     /protein_id="HBL7170641.1"
                     /translation="MRRVFWLVAAALLLAGCTGEKGIVEKEGYQLDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVETASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(8919..9242)
                     /locus_tag="LSX49_004325"
     CDS             complement(8919..9242)
                     /locus_tag="LSX49_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBL7170642.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            9368..9883
                     /locus_tag="LSX49_004326"
     CDS             9368..9883
                     /locus_tag="LSX49_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL7170643.1"
                     /translation="MRYSKLTMLIPCALLLSACTTVTPAYKDNGPRTGSCVQGGPDSV
                     AQQFYDYRIQHRSNDITALRPYLSDKLATLLSDASRDNSHRELLSSDPFSSRTTLPDS
                     AHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            10101..10829
                     /gene="artP"
                     /locus_tag="LSX49_004327"
     CDS             10101..10829
                     /gene="artP"
                     /locus_tag="LSX49_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HBL7170644.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            10847..11578
                     /gene="artJ"
                     /locus_tag="LSX49_004328"
     CDS             10847..11578
                     /gene="artJ"
                     /locus_tag="LSX49_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL7170645.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDSVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KFNTALEKVKKDGTYETIYNKWFQK"
     gene            11585..12301
                     /gene="artQ"
                     /locus_tag="LSX49_004329"
     CDS             11585..12301
                     /gene="artQ"
                     /locus_tag="LSX49_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HBL7170646.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            12301..12969
                     /gene="artM"
                     /locus_tag="LSX49_004330"
     CDS             12301..12969
                     /gene="artM"
                     /locus_tag="LSX49_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HBL7170647.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
BASE COUNT         2999 a         3447 c         3517 g         3062 t
ORIGIN      
        1 taactttaaa aggtgtgatc atgttttgtg tgcaatgtga acaaactatc cgtactccgg
       61 caggaaacgg ctgctcatac gcgcagggga tgtgtggtaa aacggcggaa acctctgacc
      121 ttcaggattt actcatcgcg acgctgcaag ggctttcggc ctgggcagtg aaagcacgtg
      181 aatacggcat catcaaccac gatgtagaca gctttgcgcc acgtgccttt ttctcaaccc
      241 tgaccaacgt taacttcgat tctccgcgta ttatcggcta cgctcgtgaa gcgattgccc
      301 tgcgcgaggc gctgaaagca caatgcctgg ctgtagatgc caacgcccgc gtcgataacc
      361 cgatggctga cctgcaactg gtgagcgacg atctcggcga gctgcaacgt caggcagcag
      421 aatttacccc taacaaagat aaagcggcga ttggcgaaaa cattctcggc ctgcgtctgc
      481 tgtgcctgta tggcctgaaa ggtgcggcgg cctatatgga acacgcgcat gttctcggtc
      541 aatacgacaa cgatatttat gcccagtacc ataaaatcat ggcgtggctg gggacctggc
      601 ctgccgatat gaacgcgctt cttgagtgtt caatggaaat cggccagatg aacttcaaag
      661 tgatgagcat tctggacgca ggcgaaaccg gtaaatacgg tcacccgacc ccaacccagg
      721 tcaatgtcaa agcgacggca ggtaaatgca tcctgatttc cggtcacgat ctcaaagatc
      781 tctacaacct gctggaacag accgaaggca cgggcgttaa tgtctacacc cacggcgaaa
      841 tgctgcctgc gcatggttac ccggagctgc gtaaattcaa gcatctggtc ggtaactacg
      901 gcagcggctg gcagaatcag caagtggagt tcgctcgttt cccaggcccc atcgtgatga
      961 cctcgaactg catcatcgac ccaaccgtag gcgcttatga cgatcgtatc tggacccgca
     1021 gcatcgttgg ctggccgggt gtgcgccatc tggatggcga agatttctct gcggtcattg
     1081 cccaggcgca acagatggcg ggcttcccgt acagcgaaat tccgcacctg atcaccgtgg
     1141 gctttggtcg ccagacactg cttggcgcag ccgatacgct gattgatctg gtgagccgtg
     1201 aaaaactgcg tcatatcttc ctgcttggcg gctgtgacgg cgcacgcggc gagcgtcact
     1261 acttcaccga tttcgccacc agcgtgccgg atgactgcct gatcctgacc ctcgcttgcg
     1321 gtaaatatcg ctttaataaa cttgagtttg gcgatatcga aggtctgccg cgtctggtag
     1381 atgctggtca gtgtaacgat gcttactcag caattattct ggcggtaacg ctggcagaga
     1441 aactgggctg cggagtcaac gatctgccgc tgtcgctggt gctctcctgg tttgaacaga
     1501 aagcgattgt cattctgctg acgctgcttt ctctgggtgt gaaaaatatc gtcaccggcc
     1561 cgactgcacc tggtttcctg acaccagacc tgctggcggt gctgaacgag aaattcggcc
     1621 tgcgttctat caccactgtt gaagaagaca tgaagcaact gttgagcgcg taaggagttt
     1681 gtcgatgacg atgccaacga atcaatgccc gtggcggatg caggttcatc acattacgca
     1741 agaaacgccg gatgtgtgga cgatttccct gatttgccac gattactacc cgtatcgcgc
     1801 cgggcaatat gcgctggtca gcgtgcgaaa ctcagcagaa acgctgcgtg cttacaccat
     1861 ttcctccacg ccaggcgtga gtgaatacat caccctgact gtgcggcgga ttgatgacgg
     1921 tgtcggctcc cggtggctga cgcgcgatgt aaaacgcggt gattatctct ggctttcgga
     1981 cgcgatgggg gaatttacct gcgacgataa agcagaagat aaattcctgt tgctggcggc
     2041 aggctgcggc gtcacgccga ttatgtcgat gcgtcgctgg ctggcgaaga accgtccaca
     2101 ggccgatgtg caggtgatct acaacgtgcg tacgccgcag gatgtgattt tcgccgatga
     2161 gtggcgtaac tatccggtaa cgctggtggc ggaaaataac gttaccgaag gctttatcgc
     2221 tggtcgtctc actcgcgaac tgctggcagg tgtccctgat ttagcctcac gtaccgtgat
     2281 gacctgtggc cctgctccat atatggattg ggtagagcag gaagtgaaaa cgctcggcgt
     2341 gacgcgtttc tttaaagaga aattcttcac cccagtagcg gaagcggcga ccagcggtct
     2401 gaaattcacc aaactgcaac cggcacgaga attttacgct ccggttggca ccacgctact
     2461 ggaggcgctg gaaagcaata acgttccggt tgtcgccgcc tgccgtgcgg gtgtttgcgg
     2521 ctgctgtaag acgaaagtga tttccggtga atatacggtg agcagcacaa tgacgctgac
     2581 cgacgccgaa atcgctgaag gttacgtact ggcctgctca tgccatccgc agggggattt
     2641 ggttttcgca taatcgcctg atgcccgatg atattccttt catcgggcta tttaaccgtt
     2701 agtgcctcct ttttctccca tcccttcccc ctccgtcaga tgaactaaac ttgttaccgt
     2761 tatcacattc aggagatgga gaaccatgaa acaaacggtt gcagcttata tcgccaaaac
     2821 actcgaatcg gcaggcgtga aacgcatctg gggagtcacg ggcgactctc tgaacggtct
     2881 tagtgacagt cttaatcgca tgggcaccat cgagtggatg tccacccggc atgaagaagt
     2941 ggcggcattt gccgctggcg ctgaagcaca acttagcgga gaactggcgg tctgtgccgg
     3001 atcgtgcggt cccggcaacc tgcacttaat caacggcctg ttcgattgcc accgcaatca
     3061 cgttccggta ctggcgattg ccgctcatat tccctccagc gaaattggca gcggctattt
     3121 ccaggaaacc cacccacaag agctattccg cgaatgtagt cactattgcg agctggtttc
     3181 cagcccagag cagatcccac aagtgctggc aattgctatg cgcaaagcgg tgcttaaccg
     3241 tggcgtttcc gttgttgtgt taccgggcga tgtggcgtta aaacctgcgc cagaaggggc
     3301 aactacccac tggtatcatg cgccacagcc ggtagtaaca ccggaagaag aagagttacg
     3361 caaactggcg caactgctgc gttattccag caatatcgcc ctgatgtgtg gcagcggctg
     3421 tgcgggggcg cataaagagt tagttgagtt tgccgggaaa attaaagcgc ctatagtcca
     3481 tgccctgcgc ggtaaagaac atgtcgaata cgataatcca tatgatgttg gaatgacggg
     3541 attaatcggc ttttcgtcag gtttccatac catgatgaac gccgatacgt tagtgctgct
     3601 cggtactcag tttccctacc gtgtgttcta cccgaccgat gccaaaatta ttcagattga
     3661 tatcaaccca gccagcatcg gcgcgcatag caaggtagat atggcgctgg tcggcgatat
     3721 caaatcaacc ctgcgcgcat tgctgccact ggtggaagaa aaaaccgaac gcaagtttct
     3781 ggataaggcg ctggaagatt accgcgacgc ccgcaaaggg ctggacgatt tagctaaacc
     3841 gagcgagaaa gccattcacc cgcaatatct ggcgcagcaa attagtcatt ttgccgccga
     3901 tgacgctatt ttcacctgtg acgttggtac gccaacggtg tgggcggcac gttatctaaa
     3961 aatgaacggc aagcgtcgcc tgttaggttc gtttaaccat ggttcgatgg ctaacgccat
     4021 gccgcaggcg ctgggcgcgc aggcaaccga gccagaacgc caggtggtcg ccatgtgcgg
     4081 cgatggcggt tttagcatgt tgatgggcga tttcctctcg gtagtgcaaa tgaagctgcc
     4141 agtgaaaatt atcgtcttta ataacagcgt gctgggcttt gtggcgatgg agatgaaagc
     4201 tggtggctat ttgactgacg gcaccgaact acacgacacc aactttgccc gaattgccga
     4261 agcctgcggc attacgggta tccgcgtaga aaaagcgtct gaaatcgatg aagccctgca
     4321 acgcgccttc tccatcgacg gtccggtgtt ggtggatgtg gtggtcgcca aagaagaatt
     4381 agccattcca ccgcagatca aactcgaaca ggccaaaggt ttcagcctgt atatgctgcg
     4441 cgcaatcatc agcgggcgcg gtgatgaagt gatcgaactg gcgaaaacga actggctaag
     4501 gtaaaaaggg tggcatttcc cgtcataata aggacatgcc atgattgatt tacgcagtga
     4561 taccgttacc cgaccgagcc gcgccatgct cgaagcgatg atggccgccc cggttgggga
     4621 cgacgtttat ggagacgacc ctaccgttaa tgctctgcag gactatgcag cagagctttc
     4681 cggtaaagaa gccgccattt ttctgcctac cggcactcag gccaacctgg tcgctctgct
     4741 cagtcactgc gaacgcggcg aagagtatat cgtcggtcag gccgcgcata actatctgtt
     4801 tgaagccggt ggcgcagcag tactgggcag tattcagccg caacccatcg acgcagctgc
     4861 cgacggtacg ctaccgctgg ataaagtggc gatgaaaatc aaacccgacg atatccattt
     4921 cgcccgcacc aaattactca gtctggaaaa cacccacaac ggcaaagtgc tgccgcgtga
     4981 atacctgaaa gaagcatggg aatttacccg cgagcgcaat ctggcgctgc acgttgacgg
     5041 tgcgcgcatt tttaatgccg tggtggctta cggctgcgaa ctgaaagaga tcacgcaata
     5101 ttgtgactcg ttcaccattt gcctgtcgaa aggtcttggg acgccagtcg gttcattact
     5161 cgtcggtaat cgtgattaca ttaaacgtgc cattcgctgg cggaaaatga caggtggcgg
     5221 gatgcgtcag tccggcattc tggctgccgc cgggatgtat gcgctgaaaa ataacgtcgc
     5281 acgtttgcag gaagaccacg ataacgccgc ctggatggcg gagcagttgc gtgaagcagg
     5341 cgcggatgtg atgcgtcagg acaccaatat gctgtttgtt cgcgtcgggg aagaaaatgc
     5401 tgccgcgtta ggcgaataca tgaaagcgag aaacgtgctg attaacgcct cgccgattgt
     5461 ccgcctggtg acccatcttg acgtctcgcg tgaacaactg gcggaagttg ccgcccactg
     5521 gcgtgcgttc ctggcgcgtt aaggagagag acgtgccgca acgcatttta gttctcggtg
     5581 ccagtggcta cattggtcaa catctggtgc acacactcag ccagcaaggg catcagatcc
     5641 tggcggcggc acgtcacgtc gacagacttg caaaactgca actggctaat gtcagttgcc
     5701 ataaagtcga tctcaactgg ccggataacc ttccggtcct gttgcagaat attgatactg
     5761 tctattttct ggtgcacagc atgggcgaag gtggtgattt tatcgctcag gagcgccagg
     5821 tggctctcaa cgtccgcgat gcgctgcgcg aagtaccggt aaagcaagtc atctttctca
     5881 gttcattgca ggcaccgcct catgaacaat ctgatcatct gcgtgctcgt caggccacgg
     5941 cggatatttt acgtgaagcg ggtgtcccgg tgaccgaact acgtgccgga attatcgttg
     6001 gcgcgggttc agcggcattc gaagtcatgc gcgatatggt ttacaacctg ccagtattaa
     6061 cgccaccacg ctgggtacgt tcacgcacta cgcccatcgc gctggaaaac ctgctgcact
     6121 atcttgtggc gctgttagat catccggctt gcgaacatcg catcttcgaa gccgctgggc
     6181 cagaagtgct cagttatcag caacagtttg aacattttat ggcggtgagc ggtaagcgcc
     6241 gctggttgct ccccatcccc ctccccaccc gctggatttc ggtgtggttt cttaatgtga
     6301 ttacttcagt accgcccacc accgccagag cgttgattca ggggctgaaa cacgatctgc
     6361 tggcggatga caccgcgtta cgtgcactca ttccacaacc gctgatcgct ttcgatgacg
     6421 cggtacgtag cacgttgaaa gaggaagaaa aactggtcaa ctccagcgac tggggatatg
     6481 acgcgcaggc ttttgctcgc tggcgaccag aatacggtta ttttgccaaa caggcggggt
     6541 ttaccgttaa aacgtctgcc agccttcagg cgctatggcg ggtggtcaat caaatcggcg
     6601 gtaaagagcg ttatttcttt ggcaatattt tgtggcagac acgggcgttg atggaccttg
     6661 cgatcggtca taagctggca aaaggccgcc cggagcgcga atatttacag accggcgatg
     6721 ctgtggatag ctggaaagtc attgtcgttg aaccggaaaa acaacttacg ttgttatttg
     6781 gcatgaaagc gccggggctg ggacgactct gttttaccct ggaagataaa ggcgactatc
     6841 gtacaatcga tgtccgtgct ttctggcatc cgcacggtat gccggggctg ttttactggt
     6901 tattgatgat ccccgcgcat ctgtttattt ttcgcggaat ggcaaaacga atcgccagac
     6961 tggcagaaca aagcacagat taatcgacaa aacctgcgtt attctttcat gtttcccatt
     7021 gcatcaaggg ggaaatcacg gaagaatgcg cacgtcattt tctcaacaac agtggattga
     7081 tatgaaggta ctggttaccg gcgccaccag cggcttaggt cgaaacgcgg tagagttttt
     7141 atgccagaaa ggcatcagcg tgcgagcgac cggtcgcaac gaggcaatgg gtaaattgct
     7201 ggaaaaaatg ggcgcagagt ttgttccggc ggatctgacc gagttggtct catcacaagc
     7261 taaagtgatg ctcgcgggca ttgatacgct gtggcactgc tccagcttta cctcgccctg
     7321 ggggacacaa caggctttcg atctggctaa cgttcgcgcc actcgccgcc tgggtgaatg
     7381 ggctgtcgcc tggggtgtgc gtaactttat tcatatctct tctccctccc tgtacttcga
     7441 ttatcaccac catcgcgata ttaaagaaga ttttcgccct caccgcttcg ccaacgagtt
     7501 tgcccgcagc aaagcagcca gcgaagaagt gatcaatatg ctttcgcagg cgaatccaca
     7561 aacgcgcttt actattctgc gcccacaaag tctgttcgga ccgcacgata aagtctttat
     7621 ccctcgtctg gcgcatatga tgcatcacta cggcagtatt ctgttaccgc atggcggcag
     7681 tgcgctggtc gatatgacct actatgaaaa tgccgtgcac gccatgtggc tggcaagcca
     7741 ggaagcgtgc gataagctac cttccgggcg tgtgtacaac atcaccaacg gcgagcatcg
     7801 cacactgcgc agcatcgtgc agaagctgat cgacgagttg aatattgact gtcgtattcg
     7861 ttcggttcct tacccgatgc tggatatgat cgcccgcagc atggagcgtt taggccgcaa
     7921 gtcagcaaaa gagccgccgc tgacccacta cggcgtctcc aagttgaatt ttgactttac
     7981 gctggatatt acgcgtgcgc aggaagagtt aggttatcag ccagtcctca ccctggatga
     8041 aggtatcgag aaaactgccg cctggctgcg cgaccacgga aaactgccgc gctaatcctg
     8101 cccgtatttc tccagcaacg cttcggcaat cgcctgagtt tctgcatccg cttcgccgtt
     8161 atataacgtc gggcggaaat gcatctggaa cgccataatc acacgccgct gctcgcgcgg
     8221 agtcatatca ggctttacgt cataaccata acgcgccaaa agctccagca atgacgcggt
     8281 ctctaccggt gtgtgcggcg cgcgcccggc aaggtaaaag ttcacccgct gcgcatccgg
     8341 ccaggcacca atcccctgct gtgccagttg ctgccaggga aataatggcc ccggatcgtc
     8401 tttgcgctgt ggcgcaatat ccgcatgtgc tactacgttt tccggcttga tgtgataacg
     8461 ggcaataata tctttcgcca gcggaataag cgcctgaatc tgtgccggtt caaacggggc
     8521 aaaatatttc actcccgccg atttttgcca gccacggttt tccagctcaa tgccaataga
     8581 ggtgtcgtta agacgcgttg ccccgcgcca ggcgctaatc cccgcatgcc aggccagttc
     8641 ttgttccggc accagttgcc agatgcgcgg tttaccgttg tatcgcggtg gcaccgcagg
     8701 gaccagataa tgcgagctga cctgcttatc ggtcagtgtc gccagcgagc tatcaaaatc
     8761 atctgcggtg tagtggatca ccagcacttt aatgcgcgga tacgccgcct gcgcctggcg
     8821 tcgggtatca agctgatatc cctctttctc gacaatgcct ttttcgcctg tgcaccctgc
     8881 cagtaacaga gcggcagcga ccagccagaa gactcttctc atcgacgcgt tttcaccgcc
     8941 gtaccgctga cgctaaccat cagcatactg ccgttttgcc cgaccgtttc gtagtcgata
     9001 tcaataccga cgacggcatc agcccccagc gctcgcgcct gggagccgag ctcctcaaag
     9061 gcaatctccc gcgctttacg cagttctttt tcgtaggcac cggagcgtcc gccaacgata
     9121 tcgcggatac cggcaaagaa atcacggaaa atattcgcgc ctaaaatcgc ttcgccagtc
     9181 accacaccgc aatattcaac gatggtctgg ccttccagag ttggggttgt agaaaattgc
     9241 atgatcgatc tccttgtttg ctaagccttc gatcttcaaa gcattatcgg actgatacgc
     9301 tattattgaa aggatatcat tattatcgta gaacgctttc aaggtgttcg cttataagga
     9361 aatcatcatg cgctatagca aattgaccat gcttatccct tgcgcactgc tactcagtgc
     9421 ctgtaccacc gtcacgccag cttataaaga taacggcccc cgcaccggtt cctgtgtcca
     9481 gggggggcct gatagtgtgg ctcaacagtt ctatgactac cgcattcaac atcgcagcaa
     9541 tgacattacc gctctgcgcc cctatttgag tgacaaactg gcaaccctac ttagcgatgc
     9601 cagccgcgat aatagtcatc gtgaattgtt aagcagcgat ccgttctcca gtcgaaccac
     9661 cttgccagac agcgcccacg tagccagtgc atcgactatc cctaatcgtg atgcccgtaa
     9721 cattccattg cgcgtggatc tcaagcaggg tgaccagggc tggcaggatg aagtgttaat
     9781 gattcaggaa ggccagtgtt gggtcatcga cgatgtgcgc tacttaggcg gtagcgttca
     9841 tgccacggcg ggtacgctcc gtcaatccat cgagaatcgc taacgtcttg atcaaccaat
     9901 aaaccccgta aattgtccgg catttcgtga ggaatgccga catttatgct cgccgaccac
     9961 cgcccccgtt attttgtgct atgtttattg aataatgcgc tttgctttta acttttaaag
    10021 cagaaatatt gcataattat tctgtcaaag gtactatctt cgacctcaat agctatcaga
    10081 ctgccagtat acgagtgtca atgagtattc aattaaacgg cattaattgc ttctacggcg
    10141 cgcatcaggc gctgttcgat atcacgctgg attgcccgca gggcgaaacg ctggtgttac
    10201 ttggccccag cggcgcgggt aaaagctcgc tgctgcgtgt actcaatctg cttgagatgc
    10261 cgcgctccgg tacgctcaac attgcaggca accatttcga tttcaccaaa accccctctg
    10321 acaaagcgat tcgcgatttg cgtcgtaacg ttggcatggt gtttcagcaa tacaacctgt
    10381 ggccgcatct gaccgtgcag caaaacctga ttgaagcgcc ctgccgtgta ctggggctga
    10441 gtaaagatca ggcgctggcc cgtgcagaaa aactgctgga acgtctgcgt cttaaacctt
    10501 atagcgatcg ttacccgctg catctttctg gtggtcagca gcagcgtgtt gctattgccc
    10561 gtgcgttgat gatggaaccg caggtactgc tgttcgatga accgaccgcc gcactggacc
    10621 ccgaaattac ggcacaaatc gtcagcatca ttcgtgagct ggcagaaacg aatattaccc
    10681 aggtgatcgt cacccacgaa gttgaagtgg cgcgtaaaac cgccagccga gtggtgtata
    10741 tggaaaacgg tcatatcgta gaacaaggcg acgcgagctg ctttaccgag ccgcaaaccg
    10801 aagcatttaa aaactatctc tctcactaag attcgggata acaacaatga aaaaagttct
    10861 gattgccgcg ttaattgcag gttttagtct ttccgccaca gcagccgaaa ccattcgttt
    10921 tgccaccgaa gcctcctatc ctccgtttga atcgattgat gcaaacaacc agatcgttgg
    10981 ttttgatgtc gacctggcgc aggcattgtg taaagagatt gatgcaacct gcactttctc
    11041 taaccaggcg tttgacagcc tgatcccaag cctgaaattc cgtcgcgtag aagcagtgat
    11101 ggcgggcatg gatatcactc cggagcgtga aaagcaggtg ctgtttacca ccccgtacta
    11161 tgacaactct gccctgtttg tgggtcagca aggcaaatac accagtgttg atcagctgaa
    11221 aggcaaaaaa gttggcgttc agaacgggac gacacaccag aagttcatta tggataagca
    11281 tccggaaatc actaccgtgc catatgacag ttaccagaac gcaaaactgg atctgcaaaa
    11341 cggtcgtatc gacagcgtat ttggtgacac cgcagtggta actgaatggc tgaaagataa
    11401 cccgaaactg gcggcagtgg gcgataaagt gaccgataaa gattacttcg gtactggcct
    11461 cggcatcgca gtacgccagg gcaacactga actgcagcag aaattcaaca ctgcgctgga
    11521 aaaagtgaag aaagatggca cttacgaaac catctacaac aaatggttcc agaagtaatt
    11581 cctgatgaat gaattttttc ctttagcaag cgccgccggg atgaccgtcg gccttgccgt
    11641 ttgtgcattg attgtcgggc tggcgctggc gatgttcttt gcggtatggg agtctgcgaa
    11701 atggcgtcct gtcgcgtggg caggttcagc gctggtaacc attctgcgtg gcctgccaga
    11761 aattctggtg gtgctgttta tctattttgg ctcctcgcag ctgctgctga cgctttcgga
    11821 tggcttcact atcaatcttg ggttcgtgca gatcccggtg cagatggaca ttgagaactt
    11881 cgacgttagc ccgttccttt gtggtgtcat cgctctgtca ctgctgtatg ccgcctatgc
    11941 ctcgcaaacg ctgcgtggtg cattaaaagc ggtgccggtg gggcagtggg aatccggtca
    12001 ggcgctgggg ctgtcgaaat cggctatctt tttccgtctg gtgatgccgc agatgtggcg
    12061 tcatgcgctg ccgggtctcg gtaaccagtg gctggtgctg ctgaaagata ccgcgctggt
    12121 cagtttgatt agtgtgaatg atttaatgct acaaaccaaa agcatcgcta cccgtaccca
    12181 ggaaccgttt acctggtaca ttgtggcggc ggcgatttac ctggtgatca ccctgctcag
    12241 tcagtacatt ctcaaacgca ttgacctgcg cgcgacacgt tttgagcgga ggcccagcta
    12301 atgtttgagt atttacccga actgatgaaa gggctgcaca ccagcctgac gctaaccgtt
    12361 gcctcgctga ttgtggcact gattctggca ttgattttta ccatcatcct gacgctgaaa
    12421 acgccggtgc tggtgtggct ggtacggggc tatatcacgc tgtttaccgg tacgccgctg
    12481 ctggtgcaga tcttcctgat ttattacggg ccgggccagt tcccgacgtt gcaggagtat
    12541 ccggcactgt ggcatttgtt gtcagaaccg tggttatgtg cgctgattgc gttgtcgctg
    12601 aacagtgcgg cgtacaccac gcagctgttt tacggtgcga ttcgcgcgat cccggaaggt
    12661 caatggcagt cctgtagcgc cctgggaatg agcaaaaaag atacgctggc gatcctgctg
    12721 ccgtacgcgt ttaaacgctc gctctcttct tattccaacg aagtggtgct ggtgttcaaa
    12781 agtacctctc tggcttacac cattacgctc atggaagtga tgggatacag ccagttgttg
    12841 tacggacgca cctacgatgt aatggtattt ggcgcggcgg ggattattta cctggtcgtc
    12901 aacggcctgc tgacgctgat gatgcgtctg atcgagcgta aagcactggc attcgaacgg
    12961 cggaattaat gtagctgcat gctgatgccg gatgcggcgt ggacgcctta tccggcctac
    13021 atagt
//
LOCUS       DAFGPF010000134        12914 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFGPF010000134 DAFGPF010000000
VERSION     DAFGPF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12914
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.134"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            178..1236
                     /gene="citC"
                     /locus_tag="LSX49_004331"
     CDS             178..1236
                     /gene="citC"
                     /locus_tag="LSX49_004331"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HBL7170648.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            1251..1547
                     /gene="citD"
                     /locus_tag="LSX49_004332"
     CDS             1251..1547
                     /gene="citD"
                     /locus_tag="LSX49_004332"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HBL7170649.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            1544..2452
                     /gene="citE"
                     /locus_tag="LSX49_004333"
     CDS             1544..2452
                     /gene="citE"
                     /locus_tag="LSX49_004333"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HBL7170650.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            2463..3995
                     /gene="citF"
                     /locus_tag="LSX49_004334"
     CDS             2463..3995
                     /gene="citF"
                     /locus_tag="LSX49_004334"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HBL7170651.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCADLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYSGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSQAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            3999..4550
                     /gene="citX"
                     /locus_tag="LSX49_004335"
     CDS             3999..4550
                     /gene="citX"
                     /locus_tag="LSX49_004335"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HBL7170652.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHAWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHSHPLGRLWDIDVLTPEGDILSRRDYSLPPRRCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            4525..5403
                     /gene="citG"
                     /locus_tag="LSX49_004336"
     CDS             4525..5403
                     /gene="citG"
                     /locus_tag="LSX49_004336"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HBL7170653.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLNGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSRLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLL
                     LMATNGDTNVASRGGEGGLRWLQREAQTLLNNGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
     gene            5454..6917
                     /gene="citT"
                     /locus_tag="LSX49_004337"
     CDS             5454..6917
                     /gene="citT"
                     /locus_tag="LSX49_004337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HBL7170654.1"
                     /translation="MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDE
                     LKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFANTMSTHLEGFSPNATVIVLVLVFYFAH
                     YLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIY
                     GCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
     gene            7031..7837
                     /gene="rna"
                     /locus_tag="LSX49_004338"
     CDS             7031..7837
                     /gene="rna"
                     /locus_tag="LSX49_004338"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HBL7170655.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANAVALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY"
     gene            8067..8477
                     /gene="rnk"
                     /locus_tag="LSX49_004339"
     CDS             8067..8477
                     /gene="rnk"
                     /locus_tag="LSX49_004339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HBL7170656.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            8833..9261
                     /gene="uspG"
                     /locus_tag="LSX49_004340"
     CDS             8833..9261
                     /gene="uspG"
                     /locus_tag="LSX49_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HBL7170657.1"
                     /translation="MYKTIIMPVDVFEMELSDKAIRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAK
                     ELDADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            complement(9382..10947)
                     /gene="ahpF"
                     /locus_tag="LSX49_004341"
     CDS             complement(9382..10947)
                     /gene="ahpF"
                     /locus_tag="LSX49_004341"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL7170658.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(11118..11681)
                     /gene="ahpC"
                     /locus_tag="LSX49_004342"
     CDS             complement(11118..11681)
                     /gene="ahpC"
                     /locus_tag="LSX49_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HBL7170659.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            12053..12799
                     /gene="dsbG"
                     /locus_tag="LSX49_004343"
     CDS             12053..12799
                     /gene="dsbG"
                     /locus_tag="LSX49_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HBL7170660.1"
                     /translation="MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQQYEASGGKLKLSVPANVSTEQMKVLSDNEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMRNK"
BASE COUNT         3074 a         3404 c         3264 g         3172 t
ORIGIN      
        1 aaataaatca aaatttcacg ccgaaatact ccttaggatg tatagcgaaa ggagaaaaag
       61 atatacctcg atcacccccc tttctcccaa gtgaaaataa aaggttatca atttgcaaca
      121 ttgaacaaca ttcgttgcaa atcgataaca acatgcacct tcaggatact atttattatg
      181 ttcggcaatg atattttcac ccgcgtaaaa cgttcagaaa ataaaaaaat ggcggaaatc
      241 gcccaattcc tgcatgaaaa tgatttgagc gttgacacca cagtcgaagt atttattacc
      301 gtaacccgcg atgaaaagct tatcgcgtgc ggtggaattg ccggaaatat tattaaatgc
      361 gttgctatca gtgaatccgt tcgcggtgaa ggactggcgc tgacattagc cactgaactg
      421 ataaacctcg cctatgagcg gcacagcacg catctgttta tttataccaa aaccgaatac
      481 gaggcgctgt tccgccagtg cggtttttcc acgctgacca gcgtacccgg cgtgatggtg
      541 ctgatggaaa acagcgccac gcgactgaaa cgctatgccg aatcgctgaa aaaatttcgt
      601 catccaggga acaaaattgg ctgcattgtg atgaacgcca atccctttac gaatggtcac
      661 cgttatctga ttcaacaggc tgcggcacaa tgcgactggt tgcatctgtt tttagtcaaa
      721 gaagattctt cacgcttccc ctatgaagac cggctggatc tggtgttaaa aggcaccgcc
      781 gatattccac gcctgactgt gcatcgcggc tccgaataca tcatctcccg cgcaacgttc
      841 ccttgctact tcattaaaga acagagcgtc attaaccatt gctacaccga aattgatctg
      901 aagattttcc gtcagtacct cgctcccgcg ctgggtgtaa ctcaccgctt tgtcggtact
      961 gaaccctttt gtcgcgttac cgcccagtac aaccaggata tgcgctactg gctggaaacg
     1021 ccgactatct ccgcaccgcc catcgaacta gttgaaattg agcggctgcg ttaccaggag
     1081 atgccgatat ccgcttcccg ggtacgtcaa ctgctggcaa aaaacgatct cacggctatc
     1141 gcgccgctgg tccctgcagt cacgctgcat tatttgcaga acctgcttga gcactcccgc
     1201 caggacgcgg cagctcgtca aaagaccccc gcatgagaaa caggtgaaaa atgaaaataa
     1261 accagcccgc cgttgcaggc acccttgagt ctggggatgt gatgatacgc atcgccccac
     1321 tcgatacgca ggatatcgac ctgcaaatca acagcagcgt tgagaaacag tttggcgatg
     1381 caattcgcac caccattctg gacgttctcg cccgctacaa cgtgcgcggc gtacagctga
     1441 atgtcgatga caaaggcgca ctggactgca ttttacgtgc acgactggaa gccctgctgg
     1501 cacgcgccag cggtatcccg gctctgccat gggaggattg ccaatgattt ccgcttcgct
     1561 gcaacaacgt aaaactcgca cccgccgcag tatgttgttt gtgcctggtg ctaatgccgc
     1621 gatggtcagc aactccttca tctacccggc tgatgccctg atgtttgacc tcgaagactc
     1681 cgtagcattg cgtgaaaaag acaccgcccg ccgcatggtt taccacgcgc tgcaacatcc
     1741 gctttatcgc gatattgaaa ccattgtgcg tgtaaacgcg ctggattccg aatggggtgt
     1801 taacgacctg gaagccgtcg ttcgcggtgg tgcggacgtt gtgcgtctgc cgaaaaccga
     1861 taccgctcag gatgttctgg atatcgaaaa agagatcctg cgtatcgaaa aagcctgtgg
     1921 tcgtgaaccc ggcagtaccg gcctgctggc ggcgattgaa tctccgctgg gcattacccg
     1981 cgcagtggaa atcgctcacg cttccgagcg tttgatcggt atcgccctcg gcgcagaaga
     2041 ctatgtgcgc aacctgcgta cagaacgctc cccggaagga actgaactgc tgttcgctcg
     2101 ctgctccatt ttgcaggccg cgcgctctgc gggtattcag gcgttcgata ccgtctattc
     2161 cgacgctaac aacgaagccg gattcctgca agaagccgcc cacatcaaac agctgggctt
     2221 tgacggcaaa tcgctgatca acccgcgtca gattgatctg ctgcacaacc tctacgcacc
     2281 gacccagaaa gaagtggatc acgcccgccg cgtcgtagaa gccgctgaag ccgccgctcg
     2341 cgaaggcctc ggcgtggttt ccctgaacgg caagatggtg gacggtccgg ttatcgatcg
     2401 cgcccgtctg gtgctctccc gtgcagaact ttccggcatc cgcgaagaat aaggcaatca
     2461 aaatgacgca gaaaattgaa caatctcaac gacaagaacg ggtagcggcc tggaatcgtc
     2521 gcgctgaatg cgatcttgcc gctttccaga actcgccaaa gcaaacctac caggctgaaa
     2581 aagcgcgcga tcgcaaactg tgcgccgatc tggaagaagc gattcgtcgc tctggtttac
     2641 aggacggcat gacggtttcc ttccatcacg ctttccgtgg cggtgacctg accgtcaata
     2701 tggtgatgga cgtcatcgcg aagatgggct ttaaaaacct gactctggcc tccagctccc
     2761 tgagtgattg ccatgcgccg ctggtagaac acattcgcca gggcgtggtt acccgcattt
     2821 atacctctgg cctgcgcggt ccactggcgg aagaaatctc ccgtggtctg ctggcggaac
     2881 cggtgcaaat ccactctcac ggcggacgtg tgcatctggt acagagcggc gaactgaata
     2941 tcgatgtggc tttcctcggc gtcccgtcct gtgatgaatt cggtaatgcc aacggctact
     3001 ccggtaaagc ctgctgcggc tccctcggct atgcaatggt tgatgccgac aacgcaaaac
     3061 aggtcgtgat gcttaccgaa gaactgctgc cttatccgca taatccggca agcattgagc
     3121 aagatcaggt tgatctgatc gtcaaagttg atcgcgttgg cgatgctgca aaaatcggcg
     3181 ctggtgctac ccgtatgacc actaacccgc gcgaactgct tattgcccgt agcgctgcgg
     3241 atgtgattgt taactctggc tacttcaaag aaggtttctc catgcagacc ggcaccggcg
     3301 gcgcttcgct ggcggtaacc cgtttcctgg aagacaaaat gcgtagccgc gatattcgcg
     3361 ccgacttcgc cctcggcggt attaccgcga cgatggttga cctgcacgaa aaaggtctga
     3421 tccgcaaact gctggatgtg cagagctttg acagccaagc tgcgcaatcg ctggcccgta
     3481 accccaatca catcgaaatc agcgccaacc aatacgctaa ctgggggtcg aaaggcgcat
     3541 cggttgatcg tctcgacgtg gtggtactga gtgcgctgga aattgacacc cagttcaacg
     3601 ttaacgtgct gaccggctct gacggcgtac tgcgtggtgc ttccggtggt cactgcgata
     3661 ccgcgattgc ctctgcgctt tccatcatcg tcgcgccgct ggtacgcggt cgtattccga
     3721 cgctggtgga taacgtgctg acctgcatca ccccgggctc cagtgtcgat attctggtca
     3781 cagaccacgg catcgctgtt aacccggcac gtccggagct ggcagaacgt ctgcaggaag
     3841 cggggatcaa agtggtttct attgagtggc tgcgtgaacg tgcgcgtctg ctgaccggtg
     3901 aaccacagcc gattgaattc accgaccgcg tcgttgccgt tgtgcgttac cgcgatggct
     3961 cggtgatcga tgttgtgcat caggtgaagg aataagccat gcacctgctt cctgaactcg
     4021 ccagccacca tgcggtgtca attcccgagc tgctcgtcag ccgggatgaa aggcaagcac
     4081 ggcaacacgc ctggctcaag cgccatcctg ttccactggt ctcctttacc gtggttgcgc
     4141 cagggccgat taaagacagc gaggtcacac gccgaatttt taatcatggc gtgacagcct
     4201 tgcgtgcctt agccgcaaaa cagggctggc aaattcagga gcaggctgca ctggtttccg
     4261 ccagcgggcc ggagggcatg ttgagcattg ccgccccggc tcgcgacctc aagctcgcca
     4321 ccattgagct tgaacatagt catcctctcg ggcggttatg ggatatcgat gtcctgacgc
     4381 ccgaaggcga cattctctcc cgccgcgatt attcactgcc gcctcgccgc tgcctgttgt
     4441 gcgagcaaag cgcagctgtt tgcgcgcgtg gaaaaaccca tcaactgacc gatttactca
     4501 accgcatgga ggcgctgcta aacgatgtcg atgcctgcaa cgtcaactaa aaccacaaag
     4561 cttgcgacgt cattaattga tgagtacgcc ctgctgggct ggcgcgccat gctgactgaa
     4621 gtcaacctgt caccgaaacc aggcctcgtg gatcgcatta actgcggtgc gcacaaagat
     4681 atggcgctgg aagatttcca ccgcagcgcg ctggcgattc agggctggtt accccgtttc
     4741 attgaatttg gtgcctgtag tgcagaaatg gcaccggaag cggtactcaa cggattacgc
     4801 ccaattggta tggcttgcga aggtgatatg ttccgcgcca ctgcgggcgt aaacacgcat
     4861 aaaggaagca ttttttcttt agggctactg tgtgcggcaa ttggccgttt gcttcagctc
     4921 aaccagccgg taacgccaac aaccgtttgt tctacggcgg caagtttctg ccgtggcctg
     4981 accgatcgcg aactgcgtac caataattca cgactgacgg caggtcaacg gttgtaccag
     5041 cagcttggcc ttaccggcgc acgcggtgaa gccgaagcag gttatccact ggtaatcaac
     5101 cacgccttgc cgcattacct cactctgctg gatcaggggt tagatcctga actggcactg
     5161 ctcgatacct tgctcctact gatggctacc aacggcgata ccaacgttgc atcgcgcggt
     5221 ggcgaggggg gcctgcgctg gctacagcgc gaggcgcaaa cactattaaa caatgggggc
     5281 atccgaaccc ccgccgatct cgattatctc cggcagttcg acagggagtg tatcgaacga
     5341 aatctcagtc caggcggcag tgccgacctg ctgattctta cctggttttt agcacagatt
     5401 taattattta agcacttgat aaatttggaa atattaattt tcggagaacc cgtatgtctt
     5461 tagcaaaaga taatatatgg aaactattgg cgcccctggt ggtgatgggt gtcatgtttc
     5521 ttatccctgt acctgacggt atgccgccgc aggcgtggca ttactttgca gtgtttgtgg
     5581 caatgattgt cggcatgatc ctcgagccaa ttccggcaac ggcgatcagt tttattgcgg
     5641 ttactatttg cgttattggc agtaattacc tgctctttga tgccaaagaa ttagctgacc
     5701 cagcgtttaa tgcgcaaaaa caggcgctga aatggggtct ggctggtttt tccagcacca
     5761 cggtatggct ggtatttggc gcatttattt ttgcattagg gtatgaagtt tccgggttag
     5821 gccgtcgtat tgcccttttc ctggtgaaat tcatggggaa acgcacgctg acgttgggtt
     5881 atgcgattgt cattatcgac attctgctgg caccgtttac accgtccaac accgcgcgta
     5941 ccgggggtac ggtttttccg gtcattaaaa acctgccgcc gctgtttaaa tcattcccga
     6001 acgatccgtc cgcgcgtcgt attggcggct atttgatgtg gatgatggtc attagtacca
     6061 gtctgagttc gtccatgttt gtcaccggtg cggcaccaaa cgtgctgggt ctggagttcg
     6121 tcagcaaaat tgccggtatc cagattagct ggttgcagtg gttcctctgc ttcctgccgg
     6181 ttggggttat cttgcttatc attgcgccgt ggctttccta cgtgctgtac aaaccggaaa
     6241 tcacacacag tgaagaagtg gcaacctggg cgggtgatga actaaaaacc atgggtgcgc
     6301 tgacgcgcag agagtggacg ctgattggcc ttgtattgct cagcttaggt ttgtgggtat
     6361 ttggcagtga agtcattaat gctactgcgg taggtctgct ggcagtttcg ctgatgctgg
     6421 cgctgcacgt tgtgccgtgg aaagacatta ctcgctataa cagcgcatgg aacacgctgg
     6481 tcaacctggc aacgctggtt gttatggcga atggcctgac ccgttctggc tttatcgact
     6541 ggttcgccaa cacgatgagt acacacctgg aaggcttctc accaaacgca acggtgattg
     6601 tactggttct ggtgttctac tttgcacact acctgtttgc cagcctgtct gcgcacaccg
     6661 caaccatgct gccggttatt ctggccgtcg gtaaagggat tccgggcgta ccaatggaac
     6721 aactgtgtat cctgctggtg ctgtctatcg gtatcatggg ctgtctgacg ccttatgcaa
     6781 ccggtcctgg ggtgattatt tacggctgtg gctatgtgaa atcaaaagat tactggcgtc
     6841 ttggcgcaat cttcggggtg atttacatct ctatgctgct gttggttggc tggccgattc
     6901 tcgccatgtg gaactaatac gttcgccaaa cgctgaataa atcatcacgc ccgccaggta
     6961 agcccacctg gcgggctttt ttatgattta atagataata ttcagtgtat gtatgagttc
     7021 cacacccatt atgaaagcat tctggcgtaa cgccgcgttg ctcgcggttt ctctgcttcc
     7081 cttctcttct gccaacgccg tggcgttgca ggcaaaacag tatggcgatt ttgatcgcta
     7141 tgtcctggcc ctctcctggc aaaccggatt ttgccagagt caacacgatc gaaatcgtaa
     7201 cgaacgagat gaatgtcgcc tgcaaaccga aacgaccaac aaagctgatt ttttgaccgt
     7261 acatggtctg tggccaggat tgcctaaatc ggttgctgcc cgtggtgttg atgaacgccg
     7321 ctggatgcgc ttcggttgcg ctactcgccc aatcccgaat ctgccagaag cacgcgccag
     7381 ccggatgtgt tcatcgccgg aaaccgggtt atcgctggaa acggcagcta aactaagtga
     7441 agtcatgcca ggagctggcg gacgttcctg cctggaacgc tacgaatatg ccaaacacgg
     7501 tgcctgcttt ggttttgatc cagacgcata cttcggcacg atggtacgcc tgaatcaaga
     7561 aattaaagag agcgaagccg gaaaattcct tgcggataac tacggtaaaa cagtgagccg
     7621 ccgtgacttt gatgccgcct ttgccaaaag ctggggaaaa gagaacgtga aagcagttaa
     7681 gctaacgtgc cagggtaacc ctgcgtattt gactgaaatt cagatctcga tcaaagctga
     7741 cgccatcaac gctccgcttt ctgccaactc attcttgcca caaccacacc caggcaactg
     7801 tggcaaaacc tttgtgattg ataaagcagg ttattaatcc tctgatttac aaaacacgct
     7861 aattcgtctt ccataaacca tgacgattaa gatttataca taatgcgcta cattgaggaa
     7921 ttccctgaat gtgacgcaaa tcacttcaaa gagtgagcaa cagtcagtat catcatgtga
     7981 gttaaaccct cgccgcctga cggtgagggt tttcttttgg gtatgtttat ctgcgacact
     8041 cgcagtaccg acgacatgga gtaaaaatgt ccagaccaac tatcatcatt aacgacctgg
     8101 atgccgaacg catcgatatt ctgctggagc aacccgccta tgctggtttg ccaatcgccg
     8161 acgcgttaaa cgcagagttg gatcgcgccc aaatgtgttc gccagaagag atgccacacg
     8221 acgtggtgac aatgaacagc cgggttaaat tccgcaatct tagcgatggc gaagtgcgtg
     8281 tgcgcacgct ggtgtatccg gcaaaaatga ccgatagcaa tactcagctt tccgttatgg
     8341 ctccggtagg tgccgcactg ctggggctgc gcgttggcga ttccattcac tgggaacttc
     8401 cgggcggcgt tgcaacccac cttgaagtgc tggaactcga ataccagcca gaagctgctg
     8461 gcgactacct gctttaatcc catctgcaca agcgataact cgctttgccc agaggatgca
     8521 ctcgcatcct ctttccgctc aaatatcaac cagatttatc attttgctct taagcgcagc
     8581 attctaatct gaactggtta ttcatctgcg gaacctcata tgagcgaagc tctcggtatc
     8641 actgcatttt atatattcat agcagcaatt attgttgctg cagtgctata ccttgaacaa
     8701 cgctggtagc gcctggtttt atttattttc cagctcaata gcaaattcag atcaaatcag
     8761 cctcgcaaat tatagattca taaccaataa tgtgctgtta tgtatacatg caaaaacaag
     8821 gagagaatgc ttatgtacaa aacaatcatc atgccagtgg atgttttcga aatggaattg
     8881 agcgacaaag cgattcgcca cgctgaattc ctcgcccagg atgacggagt tattcatcta
     8941 cttcacgtac taccggggtc agccagcctg agcctgcacc gttttgccgc tgatgtacgt
     9001 cgttttgaag agcatctgca acatgaagca gaagaacgtt tgcaaacgat ggtcagccac
     9061 ttcaccatcg atccttcccg cattaagcaa catgtccgtt ttggtagtgt gcgggatgaa
     9121 gttaacgagt tagcgaaaga acttgatgca gatgtagtag tgattggttc gcgtaaccca
     9181 tcaatttcaa ctcatctgtt gggttctaac gcctcgagcg taatccgcca cgccaatttg
     9241 ccggtgctgg ttgtgcgtta attgccagaa taagtctccc gccctgcccg gagccatccc
     9301 tgcagggctt tttaatgcca taaaaaagcc gccaggtttg accccggcgg ctaagcaatt
     9361 acaggtgaat cttacttctt cttatgcagt tttggtgcga atcaggtagt caaaagcact
     9421 cagagaggct ttggcacctt cgccagtggc gatgatgatc tgcttgtacg gaaccgtcgt
     9481 acagtcaccc gctgcgaaca cgcctttgac gttggtttcg catttcgcat caatgataat
     9541 ctcgcccatg cgattacgtt cgactgcgcc ttccagccag ttggtgttcg gcagcagacc
     9601 aatctggacg aaaataccgg ccagttcgat gttgtgaata tcgccgctga cacgatcgcg
     9661 atattccaga cctacgactt tgctaccgtc gcctttcact tccgtggttt gcgcattcag
     9721 aataatgtcg acgtttttca ggctgcgtag tttgtcctgc agaacctggt cggctttcat
     9781 ttctggcgca aattccagca gcgttacgtg ctcaacgata cccgccaggt caattgccgc
     9841 ttccacgccg gagttaccgc cgccgataac cgctacgcgt ttgcctttaa acagcgggcc
     9901 gtcgcagtgc gggcagtagg tcacgccttt ggtgcgatac tgatcttcgc caggaacgtt
     9961 catgttgcgc cattttgcac cagtcgccac gataatgctg cgtgctttca gtaccgcgcc
    10021 agaagctgtt tcaatctgat gcaggccgcc ttcaaccgct gccgggatca gtttgctcgc
    10081 gctctggctg tcgatcacat caacgtcgta ttcatcaaca tgaactttca gcgcacctgc
    10141 cagtttctgg ccttcggtct tcggtacaga aatgtagttt tcgatatcaa cggtatcgag
    10201 gatctgacca ccaaaacgtt cgcccatcag accggtacgg atgcctttac gtgcggagta
    10261 aattgctgcc gctgcacccg cagggccgga accaacgatt aatacgtcat aagcatcacg
    10321 cttgttcagc tcttctgccg cacgtttttc cgcaccagta tcaattttgg caacgatttc
    10381 agtcaacgtc atgcggccct gaccaaactc tttcccgttt acgaacactg ccggaacgcc
    10441 catcacgttg cgatcggtga tttcgttctg gaaggtgccg ccgtcaattg cagtgtgctt
    10501 gatgcgcggg ttcagtacgc tcatcaggtt cagcgcctgc accacgtccg ggcagttgtg
    10561 gcaagagagc gaataatagg tttcgaattc aaaatcaccg tcaatatggc gaatctgctc
    10621 cagcagagac tgcgcttctt tcgacggatg accaccggtc cacaacaacg ccagtaccag
    10681 cgaggtgaac tcgtggccca gcggggaacc tgcaaaacgt ggcccctggt tggaaccagg
    10741 gttggtaatc aggaaagacg gcttacgcac cggcaagctg ttatcttctt taaaggtgac
    10801 tttgtctgac agttctgcga tttcagccaa cagttccttg atttctgccg atttagcgct
    10861 gtcatccagc gtggcaatta actcaacagg cttggtcaat ttctcaaggt aagccttgag
    10921 ttgagttttc atatttgtgt cgagcatgtt tatctcctgg gctttaaaca tcatcatgca
    10981 agcggcctct gcggctagct ggatgcagct tgcatcatgg tgcggggaag aaaatcgggt
    11041 gccgcagcac ccgaagaatt aggtgaattt ccgaagtatc tcgcgccgga gttgatagcg
    11101 cgaaagacga aggaaattta gattttacca accaggtcca gagacggagc cagagttgct
    11161 tcaccttctt tccatttagc cgggcaaact tcacctgggt gagaagctac gtactgtgct
    11221 gctttgattt tacgcagcag gtcagacgcg tcacggccaa tgccttcagc ggtaacttcg
    11281 attgcctgga tgataccctg cgggtcaaca acgaaggtcg cacggtcagc cagaccttca
    11341 tcttcacgca tgttgtcgaa gttacgggtc agggcgccag tcgggtcgcc gatcatcgca
    11401 tatttgattt tagcgatggt ttcagagctg ctgtgccatg ctttgtgggt gaagtgagta
    11461 tcggtagata ctgcgtatac gtctacgccc agtttctgca gttcttcgta atggtcagca
    11521 acgtcaccca gttcggtcgg gcatacgaaa gtaaagtcag ccgggtagaa gaagaagacg
    11581 ctccagcggc cttcggtatc tttttcggtg atttcgatga attcgccgtt tttgaatgcc
    11641 tggtttttaa aaggtttaat tttggtgtta atcaaggaca tctatacttc ctccgtgttt
    11701 tcgatgagat gtaaggtaac caatttttgc cgattcggct aatgcgtttc cattatcaaa
    11761 tcgataagtt ttaccttaca accttcgtaa gacaactttg tgaactttgc accgccagcg
    11821 gcgataaaaa gtaaaatggc cccctttcca ggtgaccgtg taatctgaac taccctttgg
    11881 tatcttcagc acctgcctgc aggctgaggt gttgccctta caaatgcaac aacgacatgg
    11941 attacaacac cctcataaac aaagggcaat cacctgatct aagctcttac ctatgacagt
    12001 gataggttat gccttttact cgacttttgc actgactgaa aaggacaaat taatgttaaa
    12061 aaagatactt ttactggccc tgcttcctgc aatcgccttc gcagaggaac ttcctgcccc
    12121 agtaaaagcg attgaaaaac agggtattac aatcatcaaa acgttcgatg cccctggagg
    12181 aatgaaaggt tatctcggta agtatcagga tatgggcgtc accatctacc tgactccaga
    12241 tggtaagcac gctatctctg gttacatgta caacgaaaaa ggtgaaaacc tgagtaacac
    12301 gcttatcgaa aaagaaattt acgcacccgc cggacgtgaa atgtggcaac ggatggaaca
    12361 atcccactgg ctcctcgacg gtaaaaaaga cgcgccggtc attgtctacg tcttcgccga
    12421 tccgttctgc ccatattgta aacagttctg gcagcaggct cgtccgtggg tagattctgg
    12481 caaagtgcaa ttgagaacat tgttggttgg ggttatcaag ccagaaagcc cggcgacagc
    12541 agcggcaatt cttgcctcca aagatcccgc aaaaacctgg caacaatatg aagcctctgg
    12601 tggcaagctt aagctaagcg tgcctgcaaa cgtaagcaca gagcaaatga aagtgttaag
    12661 cgacaacgag aaactcatgg acgatctggg ggcaaatgtc acaccagcta tctattacat
    12721 gagtaaggaa aataccctgc aacaagccgt cggattaccc gatcagaaaa cgcttaatat
    12781 cattatgagg aataaataaa agataattca tggatggttg aaatacatca ttgcttttca
    12841 accatcctaa aaacgcatga attgctcgta acccacctga cagctatgct attttagaaa
    12901 atcttaatcc aaag
//
LOCUS       DAFGPF010000135        12797 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFGPF010000135 DAFGPF010000000
VERSION     DAFGPF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12797
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.135"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            100..1074
                     /gene="cysB"
                     /locus_tag="LSX49_004344"
     CDS             100..1074
                     /gene="cysB"
                     /locus_tag="LSX49_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HBL7170661.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK"
     gene            1369..1533
                     /locus_tag="LSX49_004345"
     CDS             1369..1533
                     /locus_tag="LSX49_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HBL7170662.1"
                     /translation="MLISDGDYMRLAMPSGNQEPRRNPELKRKAWLAVFLGSALFWVV
                     VALLIWKLWG"
     gene            1536..1703
                     /locus_tag="LSX49_004346"
     CDS             1536..1703
                     /locus_tag="LSX49_004346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_304581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170663.1"
                     /translation="MVGQEQLESSPLCQHSDNEPEAKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            1817..1912
                     /locus_tag="LSX49_004347"
     CDS             1817..1912
                     /locus_tag="LSX49_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170664.1"
                     /translation="MINTNMKYWSWMGAFSLSMLFWAELLWIITH"
     gene            2062..4737
                     /gene="acnA"
                     /locus_tag="LSX49_004348"
     CDS             2062..4737
                     /gene="acnA"
                     /locus_tag="LSX49_004348"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HBL7170665.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSFKV
                     LLENLLRWQDGKSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSE
                     DQVELVEKYAKAQGMWRNPGDEPIFTSVLELDMNDVEASLAGPKRPQDRVALPDVPKA
                     FAASSELEVNATHKDRLPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNI
                     NLASEPIGHDRKGEPVFLKDIWPSAQEIARAVDQVSTEMFRKEYAEVFEGTAEWKEIN
                     VTRSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTR
                     HLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSNLIGMGILPLEFPQGVTRKTLELTGEEKIDIGDLQNLQPGATVPVTLTRADG
                     SQEVVPCHCRIDTATELTYYQNDGILHYVIRNMLK"
     gene            complement(4801..5391)
                     /gene="ribA"
                     /locus_tag="LSX49_004349"
     CDS             complement(4801..5391)
                     /gene="ribA"
                     /locus_tag="LSX49_004349"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HBL7170666.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIIERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            5561..6325
                     /gene="pgpB"
                     /locus_tag="LSX49_004350"
     CDS             5561..6325
                     /gene="pgpB"
                     /locus_tag="LSX49_004350"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HBL7170667.1"
                     /translation="MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAIMLFAILAAAILMGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            6474..6782
                     /gene="lapA"
                     /locus_tag="LSX49_004351"
     CDS             6474..6782
                     /gene="lapA"
                     /locus_tag="LSX49_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HBL7170668.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVAPHSSAAKE
                     "
     gene            6789..7958
                     /gene="lapB"
                     /locus_tag="LSX49_004352"
     CDS             6789..7958
                     /gene="lapB"
                     /locus_tag="LSX49_004352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HBL7170669.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
                     IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSI
                     MMGRVFMAKAEYAKAVESLQRVISQDRELVSETLEMLQTCYQLLGKTAEWAEFLQRAV
                     EENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
     gene            8150..8887
                     /gene="pyrF"
                     /locus_tag="LSX49_004353"
     CDS             8150..8887
                     /gene="pyrF"
                     /locus_tag="LSX49_004353"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBL7170670.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDAALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQFVRELQQRDFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMAAAREALVPFGKDAPLLIAVTVLTSMEACDLADLGVTLSPADYAERLAALTQK
                     CGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSDAGDQRRIMTPEQALAAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            8887..9213
                     /gene="yciH"
                     /locus_tag="LSX49_004354"
     CDS             8887..9213
                     /gene="yciH"
                     /locus_tag="LSX49_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HBL7170671.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGIIEIQGDKRDLLKSMLEAKGMK
                     VKLAGG"
     gene            complement(9339..9557)
                     /gene="osmB"
                     /locus_tag="LSX49_004355"
     CDS             complement(9339..9557)
                     /gene="osmB"
                     /locus_tag="LSX49_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HBL7170672.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(9826..10575)
                     /locus_tag="LSX49_004356"
     CDS             complement(9826..10575)
                     /locus_tag="LSX49_004356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL7170673.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEQSKLTVHVVDI"
     gene            complement(10664..10837)
                     /locus_tag="LSX49_004357"
     CDS             complement(10664..10837)
                     /locus_tag="LSX49_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170674.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            complement(10985..>12797)
                     /gene="pdeR"
                     /locus_tag="LSX49_004358"
     CDS             complement(10985..>12797)
                     /gene="pdeR"
                     /locus_tag="LSX49_004358"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HBL7170675.1"
                     /translation="VITSSLMMSLTVDESDLSVHLVGRKINKREWGGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPTRKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQELIDHAINQADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGISLSPEHGSDSAAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSRLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
BASE COUNT         3245 a         3012 c         3228 g         3312 t
ORIGIN      
        1 gttatagtta gcaccttttt tattattaaa tcgtattagt cacccgcctg gtgtggcgaa
       61 aaaacgatgt tctgatggcg tctaagtgga tggtttaaca tgaaattaca acaacttcgc
      121 tatattgttg aggtggtcaa tcataacctg aatgtctcat caacggcgga aggactttac
      181 acatcacaac ccgggatcag taaacaagtc agaatgctgg aagacgagct gggcattcaa
      241 attttttccc gaagcggcaa gcacctgacg caggtaacgc cagcaggaca agaaataatt
      301 cgtatcgctc gtgaagttct gtcgaaagtc gatgccataa aatcggtcgc cggagagcac
      361 acctggccgg ataaaggctc gctgtatatc gccaccacgc atactcaggc acgctatgcg
      421 ttaccaaacg ttatcaaagg ctttattgag cgttatcctc gcgtttcttt gcatatgcac
      481 cagggctcgc cgacacaaat tgctgatgcc gtctctaaag gcaatgccga tttcgctatc
      541 gccacggaag cgctgcatct gtatgaagat ttagtgatgc taccgtgcta ccactggaat
      601 cgggctatag tagtcactcc ggatcacccg ctggcaggta aaaaagccat taccattgaa
      661 gaactggcgc aatatccgtt ggtgacatat accttcggct ttaccggacg ttcagaactg
      721 gatactgcct ttaaccgcgc agggttaacg ccgcgtatcg tcttcacggc aacggatgct
      781 gacgtcatta aaacttacgt ccggttaggg ctgggggtag gggtcattgc cagcatggcg
      841 gtggatccgg tcgccgatcc cgaccttgtg cgtgttgatg ctcacgacat cttcagccac
      901 agtacaacca aaattggttt tcgccgtagt acttttttgc gtagttatat gtatgatttc
      961 attcagcgtt ttgcaccgca tttaacgcgt gatgtcgttg atgcggctgt cgcattgcgc
     1021 tctaatgaag aaattgaggt catgtttaaa gatataaaac tgccggaaaa ataatttctt
     1081 gcgttatttt cggcaccttt tatgtagcga aggtgccgga atatattctc ctttgttact
     1141 tatttgtatc cggtgcacaa tatttttatc cctcatattt atagggtaaa ttacctgtaa
     1201 agtagtgtct aattacacac ctcgcaaact ccagttttca aatatctatt tcaggtcaaa
     1261 agattgaatt attcactgga gacgattcgt aaattcgctg gatttttgac taaagtttct
     1321 ttaggatttg tctcatcgta tgattaatta caccaatcgt tcaacgtctt gctgataagt
     1381 gatggcgatt atatgaggtt agcaatgcct tctggaaatc aggaaccccg ccgcaatcct
     1441 gaattaaaac gtaaagcctg gctggcggtt tttcttggtt ctgcactttt ctgggtggtt
     1501 gtcgcactgc ttatttggaa attgtgggga taaccatggt cggtcaggag caactggagt
     1561 cgtcaccatt atgtcagcat agtgacaatg aaccagaagc aaaacgggaa tgttccgtcg
     1621 ttattccaga cgactggcaa ctaacatcgc agcaacaagc ctttatagaa ctgtttgctg
     1681 aagatgatca gccgaaacaa taattatcat cattcttatt acccattttt aatgaattac
     1741 agggctttta atacaccgca gcaataacag gttgagttat ctcaacacaa agtaataacc
     1801 gttaagggtg tagcctatga tcaacacaaa tatgaaatat tggtcctgga tgggcgcatt
     1861 ttctctgtcg atgctcttct gggccgaact cctctggatc attactcact gatccctgat
     1921 cccgctgttt gctttgcctc aaggtttctc ctcttttatc aatttgggtt gttatcaaat
     1981 cgttacgcga tgtttgtgtt atctttaata ttcaccctga agagaatcag ggcttcgcaa
     2041 ccctgtcatt aaggaggagc tatgtcgtca accctacgag aagccagtaa ggacacgttg
     2101 caggccaaag ataaaactta ccactactac agcttgccgc ttgctgccaa atcactgggc
     2161 gatatcaccc gtctacccaa gtcattcaaa gttttgctcg aaaacctgct gcgttggcag
     2221 gatggtaaat cggttaccga agaggatatc cacgcgctgg cgggatggct gaaaaatgcc
     2281 catgctgacc gtgaaattgc ctaccgcccg gcaagagtgc tgatgcagga ctttaccggc
     2341 gtacctgccg ttgttgatct ggcggcaatg cgcgaagcgg ttaaacgcct cggcggcgat
     2401 actgcaaagg ttaatccgct ctcaccggtc gacctggtca ttgaccactc ggtgaccgtc
     2461 gatcgttttg gtgatgatga ggcatttgaa gaaaacgtac gcctggaaat ggagcgcaac
     2521 cacgaacgtt atgtgttcct gaaatgggga aagcaggcgt tcagtcggtt tagcgtcgtg
     2581 ccgccaggca caggcatttg ccatcaggtt aacctcgaat atctcggcaa agcagtgtgg
     2641 agcgaattgc aggacggtga atggattgct tatccggata cactcgttgg tactgactcg
     2701 cacaccacca tgatcaacgg ccttggcgtg ctggggtggg gcgttggtgg catcgaagca
     2761 gaagccgcaa tgttaggcca gccggtttcc atgcttatcc cggacgtagt gggctttaaa
     2821 cttaccggaa aattacgtga aggtattacc gccacagacc tggttctcac tgttacccaa
     2881 atgttgcgca aacatggcgt ggtggggaaa ttcgtcgaat tttatggtga tgggctggat
     2941 tcactaccgc tggcggatcg cgccaccatt gccaatatgt cgccagaata tggtgccacc
     3001 tgtggcttct tcccaatcga tgctgtcacc ctcgattaca tgcgtttaag cgggcgcagt
     3061 gaagatcagg tcgagttggt cgaaaaatat gccaaagcgc agggcatgtg gcgtaatccg
     3121 ggcgatgaac caatttttac cagtgtgtta gaactggata tgaatgacgt tgaagcgagc
     3181 ctggcagggc caaaacgccc gcaggatcgc gttgcactgc ccgatgtacc aaaagcattt
     3241 gctgccagta gcgaactgga agtgaatgcc acgcataaag atcgcctgcc ggtcgattat
     3301 gttatgaacg gacatcagta tcagttacct gatggcgctg tggtcattgc tgcgataacg
     3361 tcgtgcacca acacctctaa cccaagtgtg ctgatggccg caggcttgct ggcgaaaaaa
     3421 gccgtaactc tgggcctcaa gcggcaacca tgggtcaaag cgtcgctggc accgggttcg
     3481 aaagtcgttt ctgattatct ggcaaaagcg aaactgacac cgtatctcga tgaactggga
     3541 tttaaccttg tgggatacgg ttgtaccacc tgtattggta actcgggacc gttgcccgat
     3601 cctatcgaaa cggcaatcaa aaaaggcgat ttaaccgtcg gtgcagtgct gtccggcaac
     3661 cgtaactttg aaggccgtat ccatccgctg gttaaaacca actggctggc ctcgccgccg
     3721 ctggtggttg cctatgcgct ggcgggaaat atgaatatca atctggcttc tgagcctatc
     3781 ggccatgatc gcaaaggcga gccggtattt ctgaaagata tctggccatc ggcacaagaa
     3841 attgcccgtg cggtagacca agtctccaca gaaatgttcc gcaaagagta cgcagaagtt
     3901 tttgaaggca cagccgagtg gaaggaaatt aacgtcacac gatccgatac ctacggttgg
     3961 caggaggatt caacctatat tcgcttatcg cctttctttg atgaaatgca ggcaacacca
     4021 gcacctgtgg aagatattca cggtgcgcgg atcctcgcaa tgctggggga ttcagtcacc
     4081 actgaccata tctctccggc gggcagtatt aagcccgaca gcccggcggg tcgatatcta
     4141 caaggtcggg gtgttgagcg gaaagacttt aactcctatg gttcgcggcg tggtaaccat
     4201 gaagtgatga tgcgcggcac cttcgccaat attcgcatcc gtaatgaaat ggtgcctggc
     4261 gttgaagggg ggatgacgcg ccatttacct gacagcgatg tcgtctctat ttatgatgcc
     4321 gcaatgcgct ataagcagga gcaaacgccg ctggcggtga ttgccgggaa agagtatgga
     4381 tcaggctcca gccgtgactg ggcggcaaaa ggtccgcgtc tgcttggtat tcgtgttgtg
     4441 attgccgaat cgtttgaacg aattcaccgt tcgaatttaa taggcatggg catcctgccg
     4501 ctggaatttc cacaaggtgt gacgcgtaaa acgttagagc ttaccgggga agagaagatt
     4561 gatattggtg atctgcaaaa tctacaaccc ggcgcgacgg ttccggtgac gcttacgcgc
     4621 gcggatggta gccaggaagt cgtaccctgc cattgtcgta tcgacaccgc gacggagttg
     4681 acctactacc agaacgacgg cattttgcat tatgtcattc gtaatatgtt gaagtaacga
     4741 gtatttgctt gccggttatt ttgcttccgg caagcaaatt aattacacaa tgcaagaggg
     4801 ttatttgttc agcaaatgac ccattttctc ggctttggta tcgagataat gttcgttatt
     4861 ggggttgcga cctacaatca acggtacgcg ttcaataata ttaatccctg cttcggtcag
     4921 aatttcgact tttttcgggt tattggttaa caagcggact tcattgacgc caaggagttt
     4981 gaacatatca gcgcaaagag tgaagtcgcg ctcatcagcg gcgaagccta actggtggtt
     5041 agcctctaca gtatcgtaac cttgatcctg cagtgcgtaa gcgcggattt tattcagcag
     5101 accaatgtta cgaccttcct gacggtgata cagcaaaata ccacggcctt cctcggcaat
     5161 ttgcgtcaat gccgcttcga gctggaagcc acaatcgcag cgcaagctga acagggcgtc
     5221 accggtcaga cattcggaat ggacgcgcgc aagtaccggg gtatgcccgg aaatatcgcc
     5281 atagactagc gcgacatgat cgtgtccggt tgccagttct tcaaatccca ccatcaggaa
     5341 atcgccccat ggggttggca gtttggcttc tgccacacgt ttaagctgca tgaaattctc
     5401 cagataatgc tggttctgta ttggcttatt ttgccataac gagaaggggt tcacctaatc
     5461 acgacgcgtc gatcgttcac ggaatggcac aaatctgtca atttttcctg gaactggcat
     5521 tttcagttat gattgtggga cttatcaaaa aggagaggcc atgcgttcga ttgccagacg
     5581 taccgcagtg ggagctgcac tattgcttgt catgccagta gccgtatgga tttctggctg
     5641 gcgttggcaa cctggagaac aaagttggtt actaaaagcg gctttttggg ttactgaaac
     5701 tgtcacccag ccctggggcg tcattacaca tttgatttta ttcggctggt ttctctggtg
     5761 tctgcgtttt cgcattaagg ctgccattat gttatttgcc attctggcgg cagcaatcct
     5821 tatgggacaa ggcgttaaat cctggatcaa agacaaagtc caggaaccac gaccttttgt
     5881 tatctggctg gaaaaaacac atcatattcc ggttgatgag ttctacactt taaagcgagc
     5941 agaacgcgga aatctggtga aagaacagtt ggctgaagag aaaaatatcc cacaatattt
     6001 gcgttcacac tggcagaaag agacggggtt tgcctttcct tccggtcaca cgatgtttgc
     6061 tgccagttgg gcactgctgg ccgttggttt gctgtggccg cgtcggcgaa cgttaaccat
     6121 tgctatcttg ttggtctggg caacgggagt catgggaagc cgcctgctgc tcgggatgca
     6181 ttggccacgc gatctggttg tagctacgtt gatttcgtgg gcgctggtgg cggtggcaac
     6241 gtggcttgcg caacgaattt gtgggccatt aacaccacct gcggaagaaa atcgcgaaat
     6301 agcgcaacga gaacaagaaa gttaacgctg gttgattttc cgaatttagc ccttaaatca
     6361 tcaacaatgc gcgtggatgc catttcgcag acggcgcgaa aatggtactt taaagggcta
     6421 ttgcggtaag ttgaccataa tttattcgct ctaaccacat aacgggaagt aatgtgaaat
     6481 atttactcat tttcttactg gtgttagcga tcttcgtgat ttcggtcacg ttgggtgcgc
     6541 agaacgatca acaggtgacg tttaattatc tgttagcgca aggggagtac cgtatttcca
     6601 cattgctggc ggtattgttt gctgcggggt ttgctatcgg ttggttgatt tgcggcctgt
     6661 tctggctgcg agttcgtgtt tccctggcgc gcgctgaacg taaaataaag cgactggaaa
     6721 accagctttc acccgcgact gacgtggctg tagcgccgca ctcgtctgcg gcgaaggaat
     6781 aactttctat gctggagttg ttgtttctgc ttttgcctgt agccgctgcc tatggctggt
     6841 atatgggccg cagaagtgcg caacaaaaca agcaagatga agccaaccgc ttgtcgcgtg
     6901 attacgtagc gggggttaac ttcctgctta gtaatcaaca ggataaagcg gtagacctgt
     6961 ttctcgatat gcttaaagag gatacaggta ccgttgaagc ccaccttacg ctcggaaacc
     7021 tgttccgttc gcgtggcgaa gttgatcgcg ctattcgcat ccatcagacc ctaatggaaa
     7081 gcgcctcgct gacctatgaa cagcggcttt tggcgattca acaactgggg cgtgattaca
     7141 tggctgccgg gttatacgac cgcgcggaag acatgttcaa tcagctgaca gatgaaactg
     7201 acttccgcat cggcgcgctg caacaactgc tacaaattta ccaggctacc agcgagtggc
     7261 agaaagcaat tgatgttgcc gaacgcctgg tgaagctggg taaagataaa cagcgcgtcg
     7321 aaattgccca tttctactgt gagttagctc tgcagcatat ggccagcgac gatctcgatc
     7381 gtgccatgac tttgctaaaa aaaggtgcgg cggcagataa aaacagcgcc cgcgtatcca
     7441 tcatgatggg acgcgtgttt atggcgaaag cagaatacgc caaagccgtc gaaagtttgc
     7501 aacgtgtcat atcccaggac agagaactgg tcagcgaaac gctggaaatg ctgcaaacat
     7561 gctatcagct gttgggtaaa actgccgaat gggcagaatt cctgcagcgc gcggtggaag
     7621 agaacaccgg tgccgatgct gaattgatgc ttgcggatat catcgaagcg cgcgacggta
     7681 gtgaggctgc acaggtctat attacgcgcc agcttcagcg tcatccgacc atgcgtgtgt
     7741 tccataaatt aatggattac cacttaaatg aagcagaaga agggcgtgcc aaagagagtc
     7801 tgatggtgct gcgtgacatg gttggcgaga aggtacgtag taagcctcgt tatcgctgcc
     7861 agaaatgtgg ttttaccgca tacaccctct actggcattg tccgtcttgt cgggcctggt
     7921 caaccattaa accaattcgc ggtcttgatg gcctgtaatt tttaaaaaaa tccgacttta
     7981 gttacaacat actaattatt gatcttctat tgtgttccgg taccgacggc gcggaaaagc
     8041 ctgccagagg agaaatcgca actgttaatt ttttatttcc acgggtagaa tgctcgccgt
     8101 ttacctgttt cgcgccactt ccggtgccca tcatcaagaa ggtctggtca tgacgttaac
     8161 tgcttcatct tcttcccgcg ctgttacgaa ttctcctgta gttgttgccc ttgattatca
     8221 taatcgcgat gccgcgctgg cctttgtcga caagatcgac ccacgcgatt gtcgtctgaa
     8281 ggtcggcaaa gagatgttta cattgtttgg gccacagttt gtgcgcgaac ttcaacagcg
     8341 tgattttgat atctttcttg acctgaaatt ccacgatatt cccaacactg cagcgcacgc
     8401 tgtcgctgct gcggctgact taggcgtgtg gatggtgaat gttcatgcct ccggtggggc
     8461 gcgtatgatg gccgcagcgc gtgaggcact ggttccgttt ggcaaagatg caccgctttt
     8521 gattgctgtg acagtgttga ccagcatgga agcctgcgac ctggccgatc ttggcgtgac
     8581 actgtcacct gcagattatg cagaacgtct ggcggcactg acgcaaaaat gtggccttga
     8641 tggtgtggtg tgttctgctc aggaagctgt gcgctttaaa caggtattcg gtcaggagtt
     8701 caaactggtt acgccgggca ttcgtccgca ggggagtgat gctggcgacc agcgccgcat
     8761 tatgacgcca gaacaggcgt tggcggctgg tgttgattat atggtgattg gtcgcccggt
     8821 aacgcaatcg gtagatccag cgcagacgct gaaagcgatc aacgcctctt tacagcggag
     8881 tgcatgatga gtgattccaa cagccgtctg gtctactcaa cggaaaccgg acgtattgat
     8941 gagccaaaag cggcccctgt acgccctaaa ggcgacggtg tggtgcgtat tcagcgtcag
     9001 accagtggac gcaaaggtaa gggcgtttgc ctgattaccg gtgtcgatct cgatgatgcc
     9061 gaactgacga aactggcagc tgaactgaag aaaaaatgcg gctgcggcgg agcagtaaaa
     9121 gatggaatta ttgaaatcca gggcgataag cgtgatttat taaaatcaat gcttgaagcg
     9181 aaagggatga aggtaaaact tgcaggcggc taacataaaa agccacggat atatccgtgg
     9241 ctttcgaata ttttactgtg tgtattattc agttatttcg tactgaacag aatcaagcgt
     9301 attataattg cgagtcgata atcgacattt atttacgatt atttaccgac ctggtgacca
     9361 ataacaccac cgacggctgc accacctaat gtacccaacg tactgccatc ggtcagtact
     9421 gcaccgccta atgcccctgc acctgcgccg attgcggtgt tgcggtcccg tttagaccag
     9481 ttagaacagg cactcagaga cattgccagg gtaattgcca gaacagccgc ggtcattttt
     9541 ttgctcgtta caaacataat actctctcct gaatttatga ttcacggaag taagctctct
     9601 ataactataa tagctaagaa taagccaggt gaaattattc cgtgaaatcc gctcgcgcgc
     9661 agggttatat cacgcaggtg ataatgactt cctgttatat cgctgataat aattttatat
     9721 cttgagagtg ttaataacag gtaaatagtc ttaattatca accaggaatc atcttagagc
     9781 ggatgatttg ccaaactgca aatcatccgt agagaaggga aatggttaaa tgtcaacgac
     9841 gtgaacggtg agtttacttt gttcaagatg catcagatcg ctggcgcgta ttttcgaatc
     9901 ggtaatcacg cgattgaatc gctcaacggg gccgatggag tatgaatgta cagcaccaaa
     9961 tttcgagctg tcggtcagga ctatcgcctc gcactctttt tccagcacgg cattgaccac
    10021 atcggtacgc atcatatcgc gaccggtaaa cccagtttca ggttgccagc catcaatacc
    10081 aataaatgct ttgctgaaat gcacctgttg gatgcactgg cgtgtcaaag ggccaaccat
    10141 actttcgctt tttttctggt acacgccacc gagcaaaatg acttcacaag gcgcgtcttt
    10201 cagcaaatgc gcgatgtagc tgctgaccgt gatgatagtg acatttttct tctgctcgcc
    10261 cagagtccgg gcgagcaggg cattgctgct accattttcg ataaagatgg tttcgcccgg
    10321 ttgaaccagt gacgcggcaa actcggcgag ttcacgcttc agcgtatagt tgctcatcat
    10381 acgggtttcg acgtcatcac tatcaagcga aactgcaaaa ccatgtgcac gtcggaggta
    10441 actcagtttt tcgagggtgt tgagatcctg gcgaatggta acttcagaaa ctccagtggc
    10501 ttttgccaga tcggttacgc taacctgacc ctggtcaatg accatctgta gaatagtttg
    10561 ttgtcgggaa ttcatcgctg taattcttat aacgttataa tactaaataa aaaaatactg
    10621 acgcgccggc atcctcaaat aggaaaacct gaaggcacga ttgttaaatc tcccacggtg
    10681 ccttcgggat gtctggcgta gattcagcaa cctggcgcaa gagttctgct ttaagtatct
    10741 cgagattatg gatcgcagag tggtaatcgc ctgccacaag gatatctaac acaatatcaa
    10801 tacgttcggc aacgcgctgg gcatcaaatt cagacatcaa ggacatcctt atagcaaaag
    10861 ggggaaaatg aataatgcaa aaattgccgc taaaagagaa gggtttaaca gcaacggcta
    10921 attatcatcc gggaatacga tatataatga cggaatatag cgctaagtat atatattcat
    10981 ctacttatgc gcgcttcaga tagcgtttat accagcgttc gaaggcgacg gcgggcatcg
    11041 gtttggcaaa caaaaatcct tgtcgctcat tgatcccgtt cttggttaaa aaagcatctt
    11101 cctttgcact ttctacacct tcggcgatca cctgaagatt caatgcctgg gccacagcga
    11161 cgatcgcccg gaccagtgat tgcgagacag gctgtttgtg aatatcccga acaaaaacct
    11221 ggtcaagttt gatggcatcg atcggaaagc gcgccagttg cgaaagtgaa gagtagccgg
    11281 taccaaaatc gtccagatga acttgcgcac ctaatcggct aaattgttga ataacagaca
    11341 gtgccagttc atcattctca atcaggcagc tctccgtcag ttcaacatct atagggcagt
    11401 attcaaaatt gagttcctgg agaacctgtt tcagggcggt gaaaatggtt tgatcggcga
    11461 gctgacgtgc agaaatattt accgctactc gcaggttaat gcctttatcc cgccacttcg
    11521 ctacctggcg tacgacatcg agaatcaccc aacggcctaa aggcacaatt agccctgatt
    11581 cttcggcgta ggaaatgaag tccaacggtg gaatcaaccc acgttcaggt gactgccaac
    11641 gtactagtgc ttccagactg cgcacttcac cacgccaggt gattttcggt tgatagtgaa
    11701 taaccaactg atcgttttcc agtgctttac gcaagttggt atccagccag agatattcaa
    11761 ataccctctg attcatttct ggggtaaaaa cgcaaaattg tcctcgtccg ccttccttcg
    11821 ctgtgtacat tgctgtgtcg gcgtgacgaa taatagccgc gctgtccgaa ccatgttcgg
    11881 gagagagtga aatacctact gaacagctgg tataaacttc aattaaacca atgcgaaagg
    11941 ggagccgtaa gcgggtcaaa attcgtgatg ccattgcttc cagcgcgctt tgtgaggtat
    12001 tggatgccag taccagaaac tcatcgccac ctggacgcgc caatacctgg tcatgttcga
    12061 gacagcttaa aatagccaat gacacgtcgc gtaataactg gtcaccaaac aaatgcccat
    12121 aggcgtcgtt gaccttttta aaattatcca aatcaagata cacaacccca actttattgt
    12181 tatctgcctg attaatagcg tgatcgatta actcctgcat tgcgttacga ttcggcagtc
    12241 cggtgatact gtcggtattt gccagaatac gcagtcgctc ctgagcgcgg cgctcttcgg
    12301 taatgtcggt gccggaacag attaaaaaaa tctcgttttt gccactgccg ctgtggacaa
    12361 atttattgcg aaacagaaac agccgctggc ctttacgtgt tggtatccac agttcgactt
    12421 catatgcatt gccgcttcga aaaaatacac ggttattgcg cctggatgcc gcagcttcac
    12481 gacgactcat aaacagttta aacacgcttt gcccaatgac gtcgtgttct ttcaagcctg
    12541 tgtaatcttc acataaccga ttaaagcgct ggatattccc ccggctgtcg agaatcacta
    12601 ttgcggaatg tgcttcagaa actacctgct cagcaaagga aagcccatgt gataaatcac
    12661 gagcaaccgc cggtgtgtca tgccatgcag acgcgttgcc tccccattct cgtttattga
    12721 tttttcgtcc taccagatgc acagaaagat cgctttcatc gacggtcaga ctcatcatca
    12781 ggctggaggt gatgacc
//
LOCUS       DAFGPF010000136        12710 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFGPF010000136 DAFGPF010000000
VERSION     DAFGPF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12710
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.136"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            51..2588
                     /locus_tag="LSX49_004359"
     CDS             51..2588
                     /locus_tag="LSX49_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBL7170676.1"
                     /translation="MKGSLKKSLLLLRITIICPVFSCAAVSPSPDNSHRFSFNPDFLQ
                     LSDGDNAKNIDLNYFANASGAAPGEYTVDVVMNGELVDRQIKIDFFAQDNKLNARLTP
                     QQLERWGIDTNKLSVSSPSAYQQNIAYIIQGATEKFDANNQKLILNIPQSYLKPQDWL
                     STPPHLWDEGMPALMVNYLFNGIKQNNNGYGSRSQFLSLDSSLNLGGWRLRHNGNWST
                     NSYNKESHWQPVSVYLQHDYSFLQGGQFTVGQTSTDGAIFDSFPFEGAQFSSDDGMIA
                     PELSQYSPVVRGIAYSQAQVSVKQNGVVIYQKNVPPGPFELRDFNQIFTGDLEVEIRE
                     ADGTIRHFTQATAVLPILQRQGRLRYNLAFGKYRSSSTLNNSVSEPQFVQSSAAIGLP
                     YEYTFYGGGIKADNYAAVLLGLGKYSDFFGAFSLDVTHARSQFSQNYKSFGKQQGQSY
                     RFMYSRGFGETNTTLNITGYRYATRGYYDFDELQQIQSGFVDEKNINSYHQRSRISTT
                     ISQDLQDWGQLYLSASKDQYWDTADGYNLSASYSLPFRYISAMLSLGYNKSPYYHEAD
                     KSLFLSVSVPLNSLLNGNNLFLTTNTITNNGQVQQQVGLNGSSQDGEFNYAVAQGWQN
                     QNRGESGNINLNYRGPYAQMNGGYAWQKESSQWTYGISGGITLHPHGLTLSQPLSLDS
                     ASALVQARDAASVKVLNGSGIYTDWRGYAVVPYLNPYNRNQISLDVNSVKDNVELLNT
                     DVTVIPSRGALVSAPFKVNVGNKAIITLIQKNGEPVPFGSVVTLDSENSINSSIVADQ
                     GQVYMSGLPEEDTLIAQWGEEASQKCKTNYKLQNKKAKFSELTLQCQ"
     gene            complement(2698..2970)
                     /locus_tag="LSX49_004360"
     CDS             complement(2698..2970)
                     /locus_tag="LSX49_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL7170677.1"
                     /translation="MEIREGHNKFYINDEQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKIREYDDIRS"
     gene            complement(2982..3212)
                     /locus_tag="LSX49_004361"
     CDS             complement(2982..3212)
                     /locus_tag="LSX49_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBL7170678.1"
                     /translation="MDQALLDGGYRCYTGENIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVTTVVKVIDTCPSGALKYRHK"
     gene            3393..5024
                     /gene="dcuS"
                     /locus_tag="LSX49_004362"
     CDS             3393..5024
                     /gene="dcuS"
                     /locus_tag="LSX49_004362"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HBL7170679.1"
                     /translation="MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAVARTLADSPEIRQGLQKKAQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            5021..5740
                     /gene="dcuR"
                     /locus_tag="LSX49_004363"
     CDS             5021..5740
                     /gene="dcuR"
                     /locus_tag="LSX49_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HBL7170680.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            6311..7651
                     /gene="dcuB"
                     /locus_tag="LSX49_004364"
     CDS             6311..7651
                     /gene="dcuB"
                     /locus_tag="LSX49_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HBL7170681.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            7729..9375
                     /gene="fumB"
                     /locus_tag="LSX49_004365"
     CDS             7729..9375
                     /gene="fumB"
                     /locus_tag="LSX49_004365"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HBL7170682.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDIQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            9498..10148
                     /locus_tag="LSX49_004366"
     CDS             9498..10148
                     /locus_tag="LSX49_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HBL7170683.1"
                     /translation="MTRTLKPLILNTGALALTLILIYTGISAHDKLTWLMEVTPVIIV
                     VPLLLATAKRYPLTPLLYTLIFFHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWLAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITRAPEAITP"
     gene            complement(10145..11500)
                     /gene="melA"
                     /locus_tag="LSX49_004367"
     CDS             complement(10145..11500)
                     /gene="melA"
                     /locus_tag="LSX49_004367"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL7170684.1"
                     /translation="MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALQDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEDYKNASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKAGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            11783..12691
                     /gene="melR"
                     /locus_tag="LSX49_004368"
     CDS             11783..12691
                     /gene="melR"
                     /locus_tag="LSX49_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HBL7170685.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAILNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQTFPG"
BASE COUNT         3309 a         3172 c         3002 g         3227 t
ORIGIN      
        1 caaaacatta aactttaaca tttatttaat catctttatc gggggacaat ttgaaaggtt
       61 cattaaaaaa atccttatta ttgttaagga tcaccatcat atgtccggta ttcagttgcg
      121 ctgccgtatc tccctcacct gacaatagtc ataggttctc atttaacccc gattttttgc
      181 aattatctga tggtgataat gccaaaaata tcgatctcaa ttattttgca aacgcaagcg
      241 gtgcagctcc aggggaatat actgttgatg tagttatgaa tggggaatta gttgaccgtc
      301 agattaagat agattttttc gcgcaggaca acaagctgaa cgccagactg acgcctcaac
      361 agttggaacg ttggggaatt gatacaaata agctctccgt atcttcccca tcggcttacc
      421 agcaaaatat tgcatatatt attcagggcg caacagagaa attcgatgcg aacaaccaaa
      481 agctaatatt gaatatacca caaagctacc tcaaacctca ggattggtta agtactccgc
      541 cccatctctg ggatgaaggt atgccagcgc taatggttaa ctatctattt aacggaatta
      601 agcaaaataa taatggctac ggtagccgta gtcagttttt atctctggac agttctctga
      661 accttggtgg atggcgcctt cgccataacg gtaactggtc aacaaactca tataataaag
      721 agagccactg gcaacccgtt agtgtttatc tacagcatga ttattctttc ctgcagggag
      781 ggcaatttac tgtagggcaa acctcaacgg atggtgcgat atttgacagt tttccttttg
      841 aaggagcaca gttttcatct gatgatggca tgattgcccc agaactcagc caatatagtc
      901 ctgttgtccg tggcattgct tattctcaag cacaggtatc cgtcaagcaa aacggagttg
      961 tcatttatca aaagaacgtc ccacctggac cgtttgaatt acgcgatttt aaccaaatat
     1021 tcaccggtga cctggaggtg gaaatccgtg aggcagatgg cactattcgc cattttactc
     1081 aggcgacggc cgttttaccg attctgcaac gtcaggggcg cttacgctat aacctggcat
     1141 tcgggaaata tcgctcaagt tctactttga ataatagtgt gtctgagcct cagtttgttc
     1201 agtcttcagc agcaatcgga ttaccttatg aatatacatt ttatggtggt ggtatcaaag
     1261 cagacaacta tgcagcagtt ctgcttggcc tgggtaaata ctcagatttt tttggagcgt
     1321 tctccctgga tgtcactcat gctcgctcac aattttcgca gaattataag tctttcggaa
     1381 aacagcaagg acagtcttac cgctttatgt attcgcgtgg ttttggtgag acgaatacga
     1441 cattgaatat taccggctat cgttatgcca cacgcggtta ctacgatttt gatgagttac
     1501 aacaaattca gagtggattc gttgatgaga aaaatataaa cagttatcat caacgttcgc
     1561 gtatatcaac aacgataagt caagatcttc aggattgggg acaactctac ctctcagcaa
     1621 gtaaagatca gtactgggat accgctgatg gatataactt atctgcgagt tactcgctgc
     1681 cattccgcta tatctcggca atgctatcgc tcgggtataa taaaagcccg tattaccacg
     1741 aggctgataa atcgctgttt ttatctgtgt ctgtaccgct caactcattg ctgaatggaa
     1801 ataacctgtt cttaaccacg aataccatta cgaataatgg tcaggtgcaa cagcaggttg
     1861 gattaaacgg ctcctcacag gatggtgagt ttaactatgc cgtggcgcaa ggctggcaga
     1921 atcaaaacag aggagagtca ggtaacatta accttaacta tcgtggacct tatgcacaaa
     1981 tgaacggcgg ctatgcctgg caaaaagaat ccagtcaatg gacatacgga attagcggtg
     2041 gtattacgtt gcatccacat ggattaacct tatcccagcc attaagtctg gacagtgcca
     2101 gtgctctggt tcaggctcgt gatgccgcca gcgtaaaagt attgaacggg tcaggtattt
     2161 atacggactg gcgtggatat gccgtggtcc catatttgaa tccctataac cgaaatcaaa
     2221 tttcacttga tgttaatagt gttaaggata atgttgagct gctaaataca gatgttactg
     2281 tcatcccttc tcgaggagct ttagtttccg ctccatttaa agtcaatgtc ggtaataagg
     2341 caataattac cttgatacag aagaatggtg agcccgtacc gtttggtagt gtggtgacat
     2401 tagattctga aaatagcatt aacagcagta ttgttgctga tcaaggacag gtgtatatgt
     2461 cagggttacc tgaagaggat acacttattg cacaatgggg tgaggaggct tctcaaaagt
     2521 gtaaaacaaa ttacaaattg caaaataaaa aagcgaaatt cagtgaatta actttacaat
     2581 gccaatagtc ggtagttctt agattaataa ccctgcatat gcggggttat tttcatctaa
     2641 catattaaca acatcattcc agatttgtat tacttccggc ggacacaaat catcttttca
     2701 actgcgaata tcatcatact cccgtatttt atcaaattcg tgtttcgcaa atgggcatag
     2761 tgggataatt tttcgttttt cccgacgcat tttttccacg actttcgcaa ccagctgttt
     2821 accgatccct tgtcctttca ggctttcatc gacatcggta tgttcgataa tcgctaaatt
     2881 ctctccggtc ggcacaaaga caatttcagc gatttgcttg ccctgttcgt cattaatgta
     2941 aaatttattg tggccttcgc gtatttccat tttaccctcg cttatttatg acggtatttc
     3001 agcgcgccgc ttgggcacgt atcaatcact ttcaccacag tggtgacgtc gacttcatcc
     3061 ggcatgatcc acggctttcg tttgagatta aataacttgc cgttgccacg tacgcaattg
     3121 ccagaatgct gacatatcgc agtgttaaaa tagacatcga tattttcgcc ggtataacag
     3181 cgataacccc cgtccagtag cgcctgatcc atgaccttcc ctctctcatc agtatggttt
     3241 tcactataag catagccccg gaatcttcat acagcactgg cagtttccgt tgccagagtc
     3301 tcttccccta tatagccaat cattcttact ccctttgaat tacccgcctc atcagagata
     3361 atgcttaaga aatttgtcac acaaggaagc tgatgagaca ttcattgccc taccgtatgt
     3421 tacgcaaacg tccgatgaaa ttgagtacca cagtgatctt aatggtcagc gcggtactgt
     3481 tctcggtgct attggtggtg catctgattt acttctcgca aatcagtgat atgacgcgag
     3541 acgggctagc taacaaggca ctggcagtag cgcgtaccct cgccgactcg ccggaaatcc
     3601 gtcagggctt gcagaaaaaa gcgcaggaga gtggaatcca ggccatcgcg gaagccgtgc
     3661 gcaaacgcaa cgatctgctg tttattgtcg ttaccgatat gcaaagtctt cgctactcgc
     3721 atcctgaagc ccagcgtatt ggtcagccat ttaaaggtga tgacatcctt aaagcgctga
     3781 atggcgaaga aaatgtcgct atcaatcgcg gttttctggc gcaggcttta cgcgtattta
     3841 cccccatcta cgatgaaaat cataaacaaa ttggcgtagt ggcgatcggc cttgagttaa
     3901 gccgcgtgac ccaacagatc aatgacagtc gctggagcat tatctggtcg gtactatttg
     3961 gcatgctggt cggactgatc ggcacatgca ttctggttaa agtactgaaa aaaatccttt
     4021 tcggcctgga accctacgaa atctccacac tgtttgagca acgccaggcc atgttgcagt
     4081 ccatcaaaga aggcgtcgtt gccgtggacg atcgcggcga ggtcaccctg atcaacgatg
     4141 ccgcacaaga attgctgaat taccgtaagt cgcaggacga tgagaaactg tcgacgctaa
     4201 gccactcgtg gtcacaagtg gtagatgtct cggaagtgtt acgcgacgga accccacgcc
     4261 gcgacgaaga gattacgatt aaagaccgac tattactgat caacaccgtt ccggtgcgca
     4321 gtaatggcgt tatcatcggt gccatttcaa ccttcaggga caaaactgaa gtacgtaaac
     4381 tgatgcagcg actcgacggt ctggtcaact atgctgacgc acttcgtgaa cgatcccacg
     4441 aatttatgaa taaattgcat gtgattctcg gattattgca tctgaagagt tataagcagt
     4501 tggaagatta cattctcaaa acagccaata actatcagga agagattggc tctctgctgg
     4561 gtaagatcaa atctccggtt atcgctggtt ttttaatcag caagattaac cgcgcgaccg
     4621 atttaggcca tacgctgatt ttaaacagtg aaagccagct gccagacagc ggtagtgagg
     4681 atcaggtcgc gacgctgatt accacgttgg gaaatctgat agaaaacgcg ctggaggcat
     4741 taggaccgga acccggtggc gaaattagcg taacattgca ctaccgtcac ggctggctgc
     4801 actgcgaagt taacgatgat ggaccgggga tcgcacccga caaaatcgat cacatttttg
     4861 acaaaggtgt ctcgacaaaa ggaagcgagc gaggcgtcgg tttagcactt gtcaaacaac
     4921 aggtagaaaa tctcggcggc agcatcgccg tggaatcgga acccgggatt ttcacacaat
     4981 tttttgtcca gataccctgg gacggggaga ggtcgaacag atgatcaatg tattaattat
     5041 cgatgacgac gcaatggtcg cggagctgaa tcgccgatac gtggcacaaa tcccgggctt
     5101 tcaatgctgt ggaacggctt cgacgctgga gaaagccaaa gagattatct tcaatagcga
     5161 tacgcctatc gacctgatat tgctagatat ctatatgcaa aaagagaacg ggctcgattt
     5221 actgcctgtc ctgcataacg cgcgttgcaa aagtgatgtg attgtcatct cctccgctgc
     5281 cgatgcagca accatcaaag attcgctgca ttacggtgtt gtggattacc tgatcaaacc
     5341 cttccaggct tcccgctttg aagaggcgct caccggctgg cggcaaaaga aaatggcgct
     5401 ggaaaaacat cagtattatg accaggccga gcttgatcag ctaatccacg gcagcagctc
     5461 caacgagcag gatcctcgtc gcttgccaaa aggcttaacg ccgcagacgt tacgcacgct
     5521 gtgccagtgg attgacgcgc atcaggacta tgagttttca accgacgagc tggctaacga
     5581 ggttaacatc tcgcgtgttt cctgccgtaa ataccttatc tggctggtca actgccacat
     5641 cttgttcacc agtatccatt atggcgtcac ggggcgtccg gtttaccgtt accgtattca
     5701 ggcagaacac tactcactac tgaaacaata ttgccaataa cggatcgctg gttatctgta
     5761 agtaataatt attaccgtaa tgcaaaatac ccctggcaca agttacatcg ttcatcagta
     5821 aaacttgtgc cagatcaaat ataattatcc ctccatcatc gctaaaaatt aatatctctt
     5881 cagatgaacg gtgtttttaa tttcaaaacg ctaacaaaag ttaattaact attatgtcac
     5941 ccacattatg tgtattttta cccacaaatg ggtagatcag attaatctat aaacctaata
     6001 atacctgccc tgagaacaaa aaacagaccg ataaatatca ataagataac agcaaacaaa
     6061 acattaacat ctgcgctgta caaactataa acccatcgcc agagagtctt tctctctgaa
     6121 aaagccgctt atcacagtgc ataaatttgc cgctgcttta atcagccaat attcactgtg
     6181 aggtatttgc tcaagccggt aacgaccaaa cggatattta gtcaggctct gaaaacagtt
     6241 catacaaaac agaacgtgac tgtgatctat tcagcaaaaa tttaaatagg attatcgcga
     6301 gggttcacac atgttattta ctatccaact tatcataata ctgatatgtc tgttttatgg
     6361 tgccagaaag ggtggtatcg cgctgggttt attaggcggt atcggtctgg tcattctggt
     6421 cttcgtcttc caccttcagc caggtaaacc accggttgat gtcatgctgg ttatcattgc
     6481 ggtggtggcg gcatcggcga ccttgcaagc ttcgggcggt cttgatgtca tgctgcaaat
     6541 tgccgagaag ctgctgcgtc gcaacccgaa atatgtctca attgtcgcgc cgtttgtgac
     6601 ctgtacgctg accattcttt gcggtacggg tcatgtggtt tacaccattc tgccgatcat
     6661 ctacgacgtt gctattaaga acaacatccg tccggaacgt ccgatggcgg caagttctat
     6721 cggtgcacag atggggatta tcgccagtcc ggtgtcggtt gcggtcgtat ctctggttgc
     6781 gatgctgggt aatgtcacct ttgatggtcg ccatcttgag ttcctcgacc tgctggcaat
     6841 caccattcca tcgacgttaa tcggtatcct ggcgatcggt atcttcagct ggttccgcgg
     6901 taaagatctg gataaagacg aagagttcca gaaattcatc tccgtaccgg aaaaccgtga
     6961 gtatgtttac ggtgataccg cgacgctgct ggataaaaaa ctgccgaaaa gcaactggct
     7021 ggcaatgtgg atcttcctcg gggcaatcgc tgtagtcgcc cttcttggtg ctgattcgga
     7081 cctgcgtcca tccttcggcg gcaaaccgct gtcgatggta ctggttattc agatgtttat
     7141 gctgctgacc ggggcgctga ttattatcct gaccaaaacc aatcccgcgt ctatctcaaa
     7201 aaacgaagtc ttccgttccg gtatgatcgc catcgtggcg gtgtacggta tcgcatggat
     7261 ggctgaaacc atgttcggtg cgcatatgtc tgaaattcag ggcgtactgg gtgaaatggt
     7321 gaaagagtat ccgtgggcct atgccattgt tctgctgctg gtttccaagt ttgtaaactc
     7381 tcaggctgcg gcgctggcgg cgattgttcc ggtcgcgctg gcgatcggcg ttgatccggc
     7441 atacatcgtg gcttcagcac cggcttgcta cggttattac atcctgccga cttatccgag
     7501 cgatctggca gcgattcagt ttgaccgttc cggcaccacc cacatcggtc gcttcgtcat
     7561 caaccacagc tttattctgc cggggttgat tggtgtgagc gtatcgtgcg tcttcggctg
     7621 gatcttcgcc gcgatgtacg ggttcttata aatgcacttt gcgtgccgcc cgtaactacg
     7681 cggcacgcca ttttcgaata acaaatacag agttacaggc tggaagctat gtcaaacaaa
     7741 ccctttatct accaggcacc tttcccgatg gggaaagaca ataccgaata ttatctactc
     7801 acttccgatt acgttagcgt tgccgacttc gacggcgaaa ccatcctgaa agtggaacca
     7861 gaagccctga ccctgctggc gcagcaagcc tttcacgatg cttctttcat gctccgcccg
     7921 gcacaccaga aacaggttgc ggctattctt cacgatccag aagccagcga aaacgacaag
     7981 tacgtggcgc tgcaattctt aagaaactcc gaaatcgccg ccaaaggcgt gctgccgacc
     8041 tgccaggata ccggcaccgc gatcatcgtc ggtaaaaaag gtcagcgcgt gtggaccggt
     8101 ggcggtgatg aagaagcact gtcgaaaggc gtctataaca cctatatcga agataacctg
     8161 cgctattcac agaacgcgcc gctggacatg tataaagagg tcaacaccgg cacgaacctg
     8221 cctgcgcaaa tcgacctgta cgcggtagat ggcgatgagt acaaattcct ctgtgtcgct
     8281 aaaggcggcg gctctgccaa caaaacgtat ctctaccagg aaaccaaagc cctgctgacg
     8341 cccggcaaac tgaaaaactt cctcgtcgag aaaatgcgta ccctcggtac tgcagcctgc
     8401 ccgccgtacc atatcgcgtt tgtgattggc ggtacgtctg cggaaaccaa cctgaaaacc
     8461 gtcaagttag caagcgctca ctattacgat gaactgccga cggaagggaa cgaacatggt
     8521 caggcgttcc gcgatatcca gctggaacag gaactgctgg aagaggcaca gaaactcggt
     8581 cttggcgcgc agtttggcgg taaatacttc gcgcacgaca tccgcgttat ccgtctgcca
     8641 cgtcacggcg catcctgccc ggtaggcatg ggagtctcct gctccgctga ccgtaacatt
     8701 aaagcgaaaa tcaaccgcga aggtatctgg atcgaaaaac tggaacacaa cccaggccag
     8761 tacattccac aagaactgcg tcaggcaggt gaaggcgaag cagtgaaagt cgaccttaac
     8821 cgcccgatga aagagatcct tgcccagctt tcgcaatacc cggtatccac ccgcttgtcg
     8881 ctcaccggca ccattatcgt gggtcgcgat attgcacacg ccaagctgaa agagctgatt
     8941 gacgccggta aagaactgcc gcagtacatc aaagatcacc cgatctacta cgcgggtccg
     9001 gcgaaaacgc ctgccggtta tccatcaggt tcacttggcc caaccaccgc aggtcgtatg
     9061 gactcctacg tggatctgct gcaatcccac ggcggcagca tgatcatgct ggcgaaaggt
     9121 aaccgcagtc agcaggttac cgacgcgtgc cataaacacg gcggcttcta cctcggtagt
     9181 atcggcggtc cggcggcagt actggcgcag cagagcatca agcatctgga atgcgtcgct
     9241 tatccggagc tgggtatgga agctatctgg aaaatcgaag tagaagattt cccggcgttt
     9301 atcctggtcg atgacaaagg taacgacttc ttccagcaga tcgtcaacaa acagtgcgcg
     9361 aactgcacta agtaacctct tcggcccagc gcctggcagc atgctgccag gtgatccccc
     9421 tgggccacct cttttgcgat tgtaatttca cgcttgctgg tgaatagtca gtattttccc
     9481 tgacttgcga actcaccatg acccgcacac tcaagccgtt aattcttaac actggcgcac
     9541 tggcgctaac gttaatcctg atttataccg gcatttcggc ccatgacaaa ctcacctggc
     9601 tgatggaagt gacaccggtg attattgtcg tgccgctact gcttgccacc gctaaacgtt
     9661 atccgttaac gccgctgctt tatacgctca ttttctttca cgccatcatc ctgatggtcg
     9721 gcgggcaata cacctacgcg aaagtccccg ttggttttga ggtgcaggaa tggctggggt
     9781 tgagccgtaa tccgtatgac aaactgggac attttttcca ggggctggtg cctgcactgg
     9841 tggcacgaga gatccttgta cgcgggatgt acgttcgcgg acgtaagatg gtggcgtttc
     9901 tggtctgctg cgtggcgctg gcgataagcg cgatgtatga attaatcgag tggttggcag
     9961 cgctggcaat gggccaggga gctgatgatt ttctcggcac ccagggcgac cagtgggaca
    10021 cgcaatccga tatgttctgc gcgctgcttg gcgcattaac gacggtgata ttcctcgctc
    10081 gctttcattg ccgccagcta cggcgctttg gcttaatcac cagagcgccg gaagcgatta
    10141 ccccttaacg gtgcaaccag cctggcagcc agtcgccgtg ggcggcaatc aggtcgtcaa
    10201 caagagcata tatttcgtca atgcccagca cggcggcagt atgcgggtcc atcatcgcgg
    10261 cgtggtaaac acggtcgcga ttttccgtaa gaatagcttc tgtcagcagc gtctgtacgt
    10321 tgatgttggt ttgcatcagg gcggccagat gcgaaggtag cgtaccggct ttggtcggct
    10381 gaatgccatt agcatcaacc agacaggcca cttccacgca acatccttgt ggcaggttat
    10441 caatcaaacc atcgttacgg acattgccat aaatcacact cggctcgcca gtccagatag
    10501 cgttcatgat tgtgctggca tattcccgtg acggtttaat atcaatccgg gaggcgtttt
    10561 tataatcctc cagctcttta tgccagttcg ccagctgctc gacgcagcgt ttcgggtact
    10621 catccagcgg tactttataa cgctcaatca aatcctcacg acctggctta ataaaccacg
    10681 gtgtgtactc agcaaaatgt tctgacgatt ctgtgacgaa gtagcccagc tttttgaaca
    10741 tttcgtaacg cacaatattc tggcagcgag tattaccatg aatatttggc ttcggtgcct
    10801 gccctgcttc ataagccgcc agcaattcag gatagagatt cacgtagcta ccgtctgcgg
    10861 ttttacgctc cagttccagg taaaacgcca tatggttgat acctgcgcaa cggtaacgca
    10921 gcgtagccgg atcgatattg aggtcacgcg ccagctcttc cgccgttccc tgcaccgaat
    10981 ggcacagccc tacctgcttg atatgcggat agcgtgcata catcgcccag gtattcatcg
    11041 ccattgggtt aacgtagttg agcatggtgg catcggggca gacttccgtc atgtcctcgc
    11101 aaatctgcca caggtgcgga atggtacgta gcgcacgcat aatgccgccc ggccccagcg
    11161 tatcggcaat ggtttgttcc agaccatgcc gcttacagac ctcgaaatca gtcaccgtgc
    11221 aaggttcata accgccaatc tgaaatgcca ccaccacaaa atcagcatcc tgtaaggctt
    11281 ctttctgttg ggtgtggcag gtgattttgc cgctggcccc tgctgaatcc atcaacttgc
    11341 gcaccacaat gtgtgactct tccaggcggg tgggatcgat atccatcagg gcaatatgcg
    11401 ccgttttcag cgcctcacga tggaacacat caccaagaat atttttaacg aaaatcgtcg
    11461 aaccagcgcc gataaatgta attttaggtg cagacatcat gcagatctcc tggcttgctt
    11521 gaatgacttc atcatggcag gcgaatctgc agaaaacctc cggcttccag gttgagcatt
    11581 cccataaact catatcctaa gtggcacatc aatagatctg agtttatggg aataaattac
    11641 ctgaaaagct gaataatcga ccccaatctt ctcatccgct ctcctcgcac ctccagggag
    11701 aggaataaaa ccgtgcgcct attcgcagtc atcctccctc actcctgcca taattctgat
    11761 attccaggaa agagagtcat ccatgaatac agatacgttt atgtgcagca gcgacgaaaa
    11821 gcagacccgt agcccactgt cgctgtattc agaataccag cggatggaaa ttgagtttcg
    11881 cgcaccgcat atcatgccca ccagccactg gcatggtcag gtcgaagtga atgtgccttt
    11941 cgatggcgat gtggaatacc tgatcaacaa tgaaaaagtg aatatcaatc agggtcatat
    12001 cacgctgttc tgggcctgta caccgcacca actaacagat accggaacct gtcagagcat
    12061 ggcgattctt aatctgccga tgcatctgtt tctctcctgg ccgctggata aagacctgat
    12121 taaccacgtt actcacggca tggtgatcaa atcactggcg acacagcaac ttagcccgtt
    12181 tgaagtgcgc cgctggcagc aggaattaaa cagtccgaac gagcaaattc gccagctcgc
    12241 cattgatgaa attggcctga tgctcaagcg atttagcctc tctggctggg aaccgattct
    12301 ggtcaataaa acctcgcgca cacacaaaaa cagtgtctcg cgccatgcgc aattttatgt
    12361 cagccagatg ctgggcttta ttgccgaaaa ctatgatcag gcgctgacca tcaacgatgt
    12421 ggctgagcac gtcaaactta acgccaacta tgcaatgggg atattccagc gggtcatgca
    12481 attgacgatg aaacagtaca taaccgcgat gcgcatcaac cacgttcgcg cattactgag
    12541 cgataccgat aaaagtattc tcgatattgc cctgacggca ggctttcgtt cgagtagccg
    12601 tttttacagc acgttcggca aatatgtcgg catgtcgccg caacaatacc gcaaacttag
    12661 ccaacagcgc cgccagacgt ttcccggcta aagacgatat cagtatcagc
//
LOCUS       DAFGPF010000137        12547 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFGPF010000137 DAFGPF010000000
VERSION     DAFGPF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12547
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.137"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(281..1453)
                     /locus_tag="LSX49_004369"
     CDS             complement(281..1453)
                     /locus_tag="LSX49_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3596 domain-containing protein"
                     /protein_id="HBL7170686.1"
                     /translation="MGQTKLLKLPRGVTIRKHRQGETINITFTYKGVKCREPLSNLEV
                     TPKNIKYAERTLGEIHNKIERGTFIYAEYFPRSARLKIFGNAAAGKTVKMYLDEYLEI
                     CETRKLSPSTIGGYKKCRSALASLHICPASELTPAILKAWIQSQKTTLKTIRNQLSFL
                     RSALDEAVTDGVLQINPVSLVTASRYQSDKSEAESSYVVDPLSPAEVDALLAAAGNKQ
                     WENLFRFAIHTGLRSSELCALRWRDIDFVGKTAHVQSASVVGVIKGTKTKAGTRKVEL
                     TEEAMLALINQKPFTFMKDATVFEDPKTNKPWASADAIRKKAWVPTLRKAGIRYRNPY
                     QTRHTFATSHISRGANLFWLAAQMGHKGPEMLFRHYGSYLKEYDNFTSINHLHNHN"
     gene            complement(1414..1620)
                     /locus_tag="LSX49_004370"
     CDS             complement(1414..1620)
                     /locus_tag="LSX49_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001440432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBL7170687.1"
                     /translation="MLNLDCVPISTYCKETGETPEAINKRVQRGVWREGVQVLKVEGV
                     KERWIDLSEVAKWARQNCSNYRAA"
     gene            complement(1680..1895)
                     /locus_tag="LSX49_004371"
     CDS             complement(1680..1895)
                     /locus_tag="LSX49_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170688.1"
                     /translation="MSVIKTHTGIVITRDGEKRMKLHSTETSWVAGRCESYDKKTGYR
                     WGAPNMRRRLLLDSIRPIKQVATREQN"
     gene            complement(1892..2254)
                     /locus_tag="LSX49_004372"
     CDS             complement(1892..2254)
                     /locus_tag="LSX49_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170689.1"
                     /translation="MRINVFEMEGFLRGKCVPRDLKVNETNAEYLVRKFDALEAKCAA
                     LESKIIPVSAELPPANESVLLFDANGEGWLIGWRSLWYTWGQKETGEWQWTFQVGDLE
                     NVNITHWAVMPKAPETKK"
     gene            complement(2245..2781)
                     /gene="yfdR"
                     /locus_tag="LSX49_004373"
     CDS             complement(2245..2781)
                     /gene="yfdR"
                     /locus_tag="LSX49_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HBL7170690.1"
                     /translation="MSFIKTFSGKHFYYDRINKDNIDINDIAVSLSNICRFAGHLSHF
                     YSVAQHAVLCSQLVPQEFAFEALMHDATEAYCQDIPAPLKRLLPDYKRMEEKIDAVIR
                     EKYGLPPVMSTPVKYADLIMLATERRDLGLDDGSFWPVLEGIPATEMFNVIPLAPGHA
                     YGMFMERFNELSELRKCA"
     gene            complement(2910..3734)
                     /locus_tag="LSX49_004374"
     CDS             complement(2910..3734)
                     /locus_tag="LSX49_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2303 family protein"
                     /protein_id="HBL7170691.1"
                     /translation="MSQNLDATAINQIHALVSAQGVNEIISKIGADAVALPENFRIHD
                     LEKFNLNRFRFRGALSTASIDDFTRYSKDLADEGTRCFIDADNMRAVSVLNLGTIDEP
                     GHADNTATLKLKKTAPFSALLSVNGERNSQKSLAEWIEDWADYLVGFDANGDAIQATK
                     AAAAVRKITIEANQTADFEDNDFSGKRSLMESVEAKTKDIMPVAFEFKCVPFEGLKER
                     PFKLRLSIITGDRPVLVLRIIQLEAVQEDMANEFRDLLVEKFKDSKVETFIGTFTA"
     gene            complement(3800..4162)
                     /locus_tag="LSX49_004375"
     CDS             complement(3800..4162)
                     /locus_tag="LSX49_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416860.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170692.1"
                     /translation="MASERSTDVQAFIGELDGGVFETKIGAVLSEVASGVMNTKTKGK
                     VSLNLEIEPFDENRVKIKHKLSYVRPTNRGKISEEDTTETPMYVNRGGRLTILQEDQG
                     QLLTLAGEPDGKLRAAGR"
     gene            complement(4177..4487)
                     /locus_tag="LSX49_004376"
                     /pseudo
     CDS             complement(4177..4487)
                     /locus_tag="LSX49_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4631..5065
                     /locus_tag="LSX49_004377"
     CDS             4631..5065
                     /locus_tag="LSX49_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170693.1"
                     /translation="MSGNIYTLYKSHCENVGKYRGIEISGVVSSVEISKVESRATLLT
                     LLDLVLHEHRKKFGTPYNQLNGKKALVHLILMKHHWMPKQINEMKFDELLLSIQDELT
                     LDKISVTAQKFLDYRDWRSQIHHFDDFDENEWDPNLSAQYLK"
     gene            complement(5037..5243)
                     /locus_tag="LSX49_004378"
     CDS             complement(5037..5243)
                     /locus_tag="LSX49_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000549622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170694.1"
                     /translation="MHKTEPKIVAPGYTDEEIYEWMTKKLAAINQLREVLSYRQETID
                     SLKKLDQEITVLSQDVTLDIVQTN"
     gene            complement(5491..6117)
                     /locus_tag="LSX49_004379"
     CDS             complement(5491..6117)
                     /locus_tag="LSX49_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBL7170695.1"
                     /translation="METVGQRIKALRRVTRTSQKELGKFCGVSDVAVGYWEKDINTPG
                     GEALSKLAKFFNTSIDYILYGAEFEGKLVTNMRRVPVISWVQAGQFTECRAAEVFSEV
                     DKWVDTSLKIGDNSFALEVKGDSMTNPNGLPTIPEGATVIVDPDAEPRHGKIVIARLD
                     GTNEATVKKLVIDGPQKFLVPLNPRYPNIPINGNCLIIGVVKGVQYEL"
     gene            6215..6415
                     /locus_tag="LSX49_004380"
     CDS             6215..6415
                     /locus_tag="LSX49_004380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBL7170696.1"
                     /translation="MTTDDIESYFGSIEKVAAFFGITTEAVYQWRNRPGQLIPKGRAA
                     EAAYRTCGRLPFKPELYEKSNG"
     gene            6453..7005
                     /gene="ymfL"
                     /locus_tag="LSX49_004381"
                     /pseudo
     CDS             6453..7005
                     /gene="ymfL"
                     /locus_tag="LSX49_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415665.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmfL"
     gene            7181..7360
                     /locus_tag="LSX49_004382"
     CDS             7181..7360
                     /locus_tag="LSX49_004382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HBL7170697.1"
                     /translation="MRQVNRWFKDHYGVPVRVIRWEPETQRVIYLREGYEHECFSPLE
                     QFRRKFREIEVGHEH"
     gene            7350..8291
                     /locus_tag="LSX49_004383"
     CDS             7350..8291
                     /locus_tag="LSX49_004383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7170698.1"
                     /translation="MSTKLTGYVWDGCAASGMKLSSVAIMARLADFSNDEGVCWPSIE
                     TIARQIGAGMSTVRTAIARLEAEGWLTRKARRQGNRNASNVYQLNVAKLQAAAFSQLS
                     DSDPSKSDASKSDPSKFDASKSGKKAGFHPSESGGDPSVKSKHDPSDKKTSRPDASQP
                     DTQTAEQEFLTRHPDAVVFSPKKRQWGTQDDLTCAQWLWKKIIALYEQAAECDGEVVR
                     PKEPNWTAWANEIRLMCVQDGRTHKQICEMYSRVSRDPFWCRNVLSPSKLREKWDELS
                     LRLSPSVSTYTEKREDPYFKASYDNVDYSQIPAGFRG"
     gene            8288..8782
                     /locus_tag="LSX49_004384"
     CDS             8288..8782
                     /locus_tag="LSX49_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HBL7170699.1"
                     /translation="MSMSLLNDVQKFIEAHPGCTSGDIADAFAGYSRQRVLQSASKLR
                     QSGRVAHRCEGDTRRHFPRLTERAQEPEPQPVRETRPVRNFYVGTNDPRVILCLTRQA
                     EELESRGLYRRAATVWMAAFRESHSQPERNNFLARRERCLRKSSKRAASGEEWYLSGN
                     YVGA"
     gene            8782..9435
                     /locus_tag="LSX49_004385"
     CDS             8782..9435
                     /locus_tag="LSX49_004385"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HBL7170700.1"
                     /translation="MSNKYCQALVELRNKPAHELKEVGDQWRTPDNIFWGINTLFGPF
                     VLDLFTDGDNAKCAAYYTAEDNALAHDWSERLAELKGAAFGNPPYSRASQHEGQYITG
                     MRYIMKHASAMRDKGGRYVFLIKAATSEVWWPEDADHIAFIRGRIGFELPVWFIPKDE
                     KQVPTGAFFAGAIAVFDKTWKGPAISYIGRDELEACGEAFLAQVRQQAEKLVREMAA"
     gene            9432..9758
                     /locus_tag="LSX49_004386"
     CDS             9432..9758
                     /locus_tag="LSX49_004386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003878599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBL7170701.1"
                     /translation="MTTLTQCQQQVLDMLISYQKERGFPPTNQEVATMLGYRSVNAAV
                     EHLRALEKKGVITIKRGVARGITLHTAVKDDDSEAVGIIRALLAGEENARLRATHWLH
                     ERDLKV"
     gene            9755..10144
                     /locus_tag="LSX49_004387"
     CDS             9755..10144
                     /locus_tag="LSX49_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBL7170702.1"
                     /translation="MKLILPFPPSVNTYWRHPNKGAFAGKSLISAAGRKFQSAACAAI
                     VEQLRRLPKPTSAPASVEIVLFPPDNRIRDLDNYNKALFDALTHAGVWEDDSQVKRML
                     VEWGPVIPEGKVEITISKYEKTAGAAA"
     gene            10164..10961
                     /locus_tag="LSX49_004388"
     CDS             10164..10961
                     /locus_tag="LSX49_004388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HBL7170703.1"
                     /translation="MNNLMVIDGIEVRRDAYGRYSLNDLHRAAGSLDKHKPAFWLRNE
                     QTERLISELQICNSVNIAPVNVIRGGNNQGTYVCKELVYAYAMWISPSFHLKVIRTFD
                     MVTSAPEKLSGQAADKMQAGVILLDFMRRELNLSNSSVLGACQKLQEAVGLPNLAPRY
                     AIDAPADAPDGSSRPTLSLSALLKQYGIRLTANQAYHQMVKLGIVEQRERYSRTAINN
                     IKKFWSLTAKGCMFGKNITSPANPRETQPHFFESRFPELLKLLDTVH"
     gene            10969..11958
                     /locus_tag="LSX49_004389"
     CDS             10969..11958
                     /locus_tag="LSX49_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HBL7170704.1"
                     /translation="MRALLTPEIAPRMGIVLFRPGSELMPLFMQGRVLLEPEPERYSS
                     FASGAVPAASQPLADDPAVRAVFRNEAVIRRAGGVECLESWLLREKGCQWPHSDWHSE
                     NMTTMRHAPGAIRLCWHCDNQLRDQFTERLESMATDNCARWVLSVVRRDLGFDDSHVV
                     TMPELCWWLIRNDLADALPESAARKALRLPKPVVPSVTRESDLVPSVPATSIIQDKAK
                     KVLALKVDPESPESFMLRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGG
                     MGTKAHDLFVLPLCRKHHDELHADTVAFEEKYGSQLELIFRFIDRALAIGVLA"
     gene            11976..12317
                     /locus_tag="LSX49_004390"
     CDS             11976..12317
                     /locus_tag="LSX49_004390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HBL7170705.1"
                     /translation="MRDMYEVLDRWGAWAAADNSGVDWQPVAAGFKGLLPHGKKTRQQ
                     CDDDEGIMIDSCVARLRKYKPEEYELVIAHFVIGISLRAIAKKQKCSDGTIRKELQTA
                     LGFLDGVLSML"
BASE COUNT         3197 a         2880 c         3144 g         3326 t
ORIGIN      
        1 cctatgtttg aaaattttgt ttgtggaagc gtaggggctt gtaagatatc aacatgaaaa
       61 ccgttgaaat cgttaacatt catcttgata tttaaagtgt ctatcactaa attgggttta
      121 taagagagcc ttctttgaaa tatcgttaac catattgcat ataatgcagc aattgctgaa
      181 atgaaagtac caactgaaga tatgtaggtg attagtttgt cgaatgtaat tgtaatcaac
      241 tttaaatccc cgattttaaa aatgcgggga ttattaaata ttaattatga ttatgcaaat
      301 gatttatcga tgtaaagtta tcatactctt taagatacga accatagtgc ctgaaaagca
      361 tctccggccc tttatgcccc atttgagctg caagccaaaa caggtttgct cctcggctga
      421 tatggctggt ggcgaatgta tgcctggttt gatatgggtt tctgtaacga atacctgctt
      481 ttcgcaatgt tggcacccat gcttttttcc taattgcatc agcacttgcc caaggcttat
      541 tggtctttgg atcttcaaag acagtagcat ccttcatgaa tgtaaatggc ttctgattta
      601 tcagcgccaa cattgcctct tctgtcagtt caactttccg agtacctgct tttgtctttg
      661 tccctttgat aacaccgaca acacttgcgc tctggacatg ggcagttttt ccaacaaagt
      721 cgatatcacg ccatcgaagg gcacataatt cagaactacg caggcctgta tgtatagcga
      781 accggaacag attttcccat tgtttgtttc cggctgctgc tagtaatgca tcaacttctg
      841 ctggtgatag cggatcaacc acgtagctgc tttctgcttc tgacttatca ctttggtagc
      901 gcgaagcagt taccaacgat acggggttaa tttgaagtac cccatcggtt acggcttcat
      961 caagtgctga ccgcaggaaa gataactggt tgcgaattgt ttttaaggtc gttttctggc
     1021 tttgaatcca cgctttcagg attgctggtg ttaattcact tgcagggcaa atgtggagtg
     1081 aggctaacgc actacggcat tttttataac caccaatcgt agagggtgaa agttttctcg
     1141 tttcgcagat ttcaaggtat tcgtccaggt acatttttac cgttttgcct gcagcagcat
     1201 taccaaaaat tttcaaacga gcagaacggg gaaaatattc cgcataaatg aatgttcccc
     1261 tttcgatctt attatgaatt tcgccgagtg tgcgctcggc gtattttatg ttctttggtg
     1321 ttacttccag attggaaaga ggctcacgac atttaactcc tttgtaggtg aaagttatat
     1381 tgatcgtttc gccctggcgg tgtttcctga ttgttacgcc gcgcggtagt ttgagcagtt
     1441 ttgtctggcc cattttgcaa cctcactaag atcaatccac ctctccttaa cgccttcaac
     1501 ctttaaaacc tgaacacctt cacgccaaac accgcgctgt acacgtttgt ttattgcttc
     1561 aggagtttcg ccagtttctt tgcaataagt tgagattgga acacaatcga ggttcagcat
     1621 atgtttctcc acttagcccg ctgcacacgg gcagtaatat caaattccag tcctgataat
     1681 taattttgtt ccctggttgc tacctgtttt attggcctga tgctgtccag tagcagacgg
     1741 cgacgcatgt taggtgcccc ccaacggtaa ccagtctttt tgtcgtagga ttcacaacgt
     1801 ccggcaaccc aggacgtttc agtggaatgt aatttcattc gcttttcacc gtctcgggtg
     1861 ataacaattc ctgtatgagt ttttatcacg ctcatttctt agtctctggt gctttcggca
     1921 ttactgccca gtgagtgata ttgacgtttt caaggtcccc gacctgaaat gtccactgcc
     1981 attctccggt ttctttttgt ccccaggtgt accagagaga acgccagcca atcagccagc
     2041 cttctccgtt agcatcaaat aacagaacac tttcatttgc tggtggcagt tcagctgaca
     2101 ctggtattat tttgctttcc agtgccgcac atttagcttc aagcgcgtcg aatttacgta
     2161 ccaggtactc agcatttgtt tcgttcactt tcagatctcg cggtacacat ttcccgcgaa
     2221 gaaacccttc catttcgaaa acatttatgc gcatttgcgt aactccgata attcgttaaa
     2281 gcgttccata aacatcccgt aggcatggcc tggagccagt ggaatcacgt tgaacatctc
     2341 tgttgccggg ataccttcca gcacaggcca gaaagagcca tcatcaagcc cgagatcgcg
     2401 gcgttcggtt gccagcatga tgagatcggc atatttcacg ggtgtactca taaccggggg
     2461 taacccgtat ttctcacgga ttacggcgtc tattttttct tccatccgtt tatagtcagg
     2521 aagaaggcgt ttcagtggag ccgggatgtc ctggcaatac gcttctgttg catcatgcat
     2581 taacgcttca aaagcaaatt cctgcggtac cagctggctg caaagcaccg catgttgggc
     2641 gacgctgtag aagtgtgaaa gatggccggc aaagcgacag atatttgaaa gggaaaccgc
     2701 gatatcgtta atatcgatgt tgtctttatt tatcctgtca tagtaaaaat gcttcccgga
     2761 aaaagtttta ataaatgaca ttttgttctc cacgttatat gcgctgcacc gcgctgaatt
     2821 ttggttaaag aaaaccctcg ccttcaggcg attattgagt caattacatt tccataaatg
     2881 cccccgcagg ggcatttgca gtaatgaaat caggcggtga aagtcccaat aaaggtttct
     2941 actttgctgt ccttgaattt ctcaacaagc agatcacgaa attcgttagc catatcttcc
     3001 tgcaccgctt ccagctgaat aatgcgcaga accagtaccg gacgatcgcc agtgataatg
     3061 ctgaggcgta atttaaacgg acgttctttc agaccttcaa acggaacgca tttaaactca
     3121 aatgccactg gcataatgtc tttggtcttc gcttcgacag actccatcag ggagcgtttg
     3181 ccgctgaagt cattatcttc aaaatcagca gtctggtttg cttcaatcgt gattttacgg
     3241 accgccgcag ccgcttttgt tgcctgaatg gcatcaccat tagcatcaaa gcccacaagg
     3301 tagtcggccc agtcttcaat ccattctgcc agagacttct gggagttacg ctcgccgtta
     3361 acagacaata gtgcagagaa cggtgctgtc tttttcagtt tgagagtggc ggtgttatct
     3421 gcgtgacctg gttcatcaat agtacccagg ttaagcacac tgacggcacg catattatcg
     3481 gcatcgataa agcagcgggt gccttcatct gcaagatctt tagaataacg ggtaaagtca
     3541 tcgatgctgg cagtggaaag cgcaccacgg aaacggaagc gatttaaatt aaatttttcc
     3601 agatcatgaa tgcggaaatt ctcaggcaat gccacagcat cggcaccaat cttactgata
     3661 atttcattaa caccctgagc agaaacaagg gcatggattt gattaattgc ggttgcgtct
     3721 aagttctgag acataataag tcctcactat ataaagatat tcagtgatga gataaataat
     3781 cagtttatta agaacgatat taacgacctg ctgcgcggag ttttccgtca ggttcaccgg
     3841 caagagtcag taattgtccc tggtcttcct gcagaatagt caggcgacca ccgcgattga
     3901 catacatcgg cgtttcggtg gtgtcttctt cagaaatttt cccgcggtta gtcgggcgaa
     3961 catatgagag tttgtgtttg attttcacac ggttctcatc aaatggttcg atttccaggt
     4021 tgagtgagac cttacctttg gttttcgtgt tcatcacacc ggaagcgact tcactgagaa
     4081 ctgcgccgat tttggtttca aatacgccgc cgtccagctc cccgataaat gcctgcacat
     4141 cagtactgcg ttcgctagcc attttgctgc tcctcatcat atcgaccctg caaggtcggt
     4201 tagtttctcc acaaaacaga gaagaacacc tgcggtgact gccgcccgga tggattgggt
     4261 tatgagcccg tcgtccggtg atgctcttct ctgttttgta aaaaggacgg taccagccgg
     4321 aagcaagggt acaagctggt accgccaaga ctacacacag cataaagttg tggtgccggg
     4381 tgcctcccgg tgcctggcga aggttgcaca ctaggcgggt gggtatccac agaaggtcga
     4441 ctgtcagcct caaccttaac ccgcgtgcgc tgagccgcat tcaccacaac gctaaggatt
     4501 ctctctggtt gaaaatactt agctgttatg tgcctgcttt tagccacatc aggcgaggtg
     4561 gacctggtta ttccccaaca acaaggattc ggttaatctg gttatcccca acaacgcaaa
     4621 aggaaaagaa atgtccggta atatctatac gctgtacaaa tcccactgtg aaaatgttgg
     4681 aaagtatcgg ggcattgaaa tcagtggggt agtgtcatca gtcgaaataa gcaaagttga
     4741 atcaagggca acattactta ctcttttgga ccttgtctta catgagcacc ggaagaaatt
     4801 cggcactccc tataatcagt tgaatgggaa aaaggctctg gttcacctta ttctgatgaa
     4861 gcatcactgg atgccaaaac agattaatga gatgaaattt gatgaacttc ttctttcaat
     4921 tcaggatgaa ctcacacttg ataaaataag cgtaaccgcc cagaaatttt tagattatcg
     4981 agactggaga tcacaaattc atcactttga tgattttgac gaaaatgaat gggatcctaa
     5041 tttgtctgca caatatctaa agtaacatcc tgtgataaaa ccgtgatttc ctgatccagt
     5101 ttttttaagg agtctattgt ttcctgtcga taagacagca cttcacgaag ctggtttata
     5161 gctgccagct tctttgtcat ccactcataa atttcctcat ctgtgtagcc aggcgcgacg
     5221 attttgggtt ctgttttgtg catttcacat ctcctcaagt tatcagttac ttgttgatgg
     5281 ggaccagatt gttaaagagc taagcgtcct gtagggcgct tttttgttgc taacgaatca
     5341 tcctggactt catatgcccc aggcggctac ttcgtgggcg tcctgcctgt tcgttatctt
     5401 tgacataaaa tctaacttaa cttagttatt atggcaagag aaaacaccaa acttttctta
     5461 gttcggtgcc ttagttagag aagagaggtc ttagagttcg tattgaactc ctttgactac
     5521 accaatgata aggcaattac cattgatagg gatgttggga taccgaggat ttaatggcac
     5581 taaaaacttt tgagggccat cgatgactaa tttttttact gtagcttcgt ttgttccatc
     5641 aagtcgagcg atgactattt ttccatgacg aggttctgca tctggatcta caatcactgt
     5701 tgcgccttct ggtattgttg ggaggccatt agggttagtc atggagtcac ctttaacctc
     5761 taatgcaaat gagttatcac caatctttaa tgatgtatct acccacttgt ccacttcact
     5821 aaacacttct gctgccctgc actcagtaaa ctgcccagcc tgaacccacg atattacagg
     5881 aactctgcgc atgtttgtga cgagtttgcc ttcaaactca gcaccataaa gaatgtaatc
     5941 tattgacgta ttgaagaact tcgctaattt cgaaagtgcc tccccaccag gggtattgat
     6001 gtctttctcc cagtacccca cagcaacgtc gcttactcca caaaatttac ccaattcttt
     6061 ctgggacgtt ctggtaactc ttctcagagc ttttatacgc tgaccaaccg tttccatagg
     6121 agcaccattt ctttaattac taagtaatct tagtttttat tgaccaaaga tagatttgta
     6181 attagcatct aataaaactt agtttggagg gcgtatgaca actgacgata tcgaaagcta
     6241 cttcggcagt attgagaaag ttgctgcttt tttcggcata acaactgaag ccgtttatca
     6301 gtggcgaaac cgtccgggcc agttaattcc aaaaggacgt gcagcagaag ctgcatatag
     6361 aacttgcgga cggttgccat ttaaacctga gctttatgaa aaatctaatg gataaatcga
     6421 ttaacagaaa ccacagaacg atgaggctaa ccgtgggtaa gcatcactgg aaagtagaaa
     6481 aacagcctga gtggtacgtg aaagctgtca gaaaaactat cgcagcgttg ccgggggggt
     6541 tacgctgaag ctgctgactg gctggatgta acagagaacg cattatttaa ccgccttcgt
     6601 gccgatggcg atcagatttt cccgctggga tgggcaatga ttttgcaacg tgctggtgga
     6661 actcacttca ttgcagatgc tgtggcgcag tctgcaaatg gcgtctttgt gtctcttcct
     6721 gacgtcgagg atgtggacaa cgctgatatt aaccagcgtc tgctggaagt cattgaacag
     6781 atcggcagtt attcaaaaca gattcgttca gcaatcgaag acggtgtagt ggaaccgcat
     6841 gagaagacag caattaatga cgagctctac ctctcaattt cgaagctgca ggagcatgca
     6901 gcactggtct acaaaatttt ttgcatttca gaaagtaatg acgcccgcga gtgtgcagct
     6961 ccgggcgccg tggcgtgtcg tgactgtgga gaaactaacg catgaacagt ttaacaacac
     7021 actaccgtcg ctcgcaactg attgcgcttc ctgtaccggg tggaaaagcg aaggtggaat
     7081 attgctatgc agtgaatgta ccaggtgaca gggaaattgt aacccacagc tttgcagagt
     7141 gggctgtggg tgatttcaac cggcagaagg agacagtcct ttgcgacaag ttaaccgctg
     7201 gttcaaagat cactacggag tgcccgtcag agtcattcgt tgggagccgg aaacacaacg
     7261 tgttatctac ctccgcgaag gctatgagca tgagtgcttc agcccgctcg aacagtttcg
     7321 tcgtaaattc agggaaatag aggtcggtca tgagcactaa attaaccggc tatgtatggg
     7381 atggttgcgc tgcatcaggc atgaaattat ccagcgtggc aattatggcc cgcctggctg
     7441 atttcagtaa tgacgaaggt gtgtgctggc catcaattga aaccattgcc cgccagattg
     7501 gcgcgggaat gagtaccgtc agaacggcta tcgcacggct ggaagcagaa ggctggttaa
     7561 cgcgtaaggc gcgtcgccag ggtaaccgca atgcgtcgaa tgtttatcag cttaacgttg
     7621 cgaagcttca ggcagcggca ttttctcaac tgtcagattc tgacccgtca aaatctgacg
     7681 catcaaaatc tgacccgtca aaatttgatg cgtcgaaatc tggcaaaaaa gcgggttttc
     7741 acccgtcaga atctggcggg gatccgtcag taaaatcaaa acatgatccg tcagataaaa
     7801 aaacttctcg tccggacgct tcgcaaccgg acacgcagac ggctgaacag gagtttttaa
     7861 ctcgccatcc tgatgcggtt gtattcagcc ctaaaaagcg ccagtgggga acgcaggatg
     7921 atttgacctg cgcacagtgg ctctggaaaa aaatcatcgc cctgtacgag caggccgccg
     7981 aatgtgacgg cgaggtggtt cgtcccaaag aaccgaactg gacagcctgg gcaaacgaaa
     8041 ttcgcctgat gtgtgtgcag gatggtcgta ctcataaaca aatctgcgag atgtacagcc
     8101 gcgtcagtcg cgatccgttc tggtgccgta acgtgctcag cccgtcgaag ctgcgggaaa
     8161 aatgggatga gctttccctg cgcttatcgc cgtccgtcag cacgtacacc gaaaaacgcg
     8221 aagacccgta cttcaaagcc agttacgaca acgtggacta cagccagatc ccggcaggat
     8281 tcagggggtg agcatgagtc ttttgaatga cgttcagaaa ttcattgaag cccatccggg
     8341 ctgtacttcc ggagatattg cggatgcttt tgccggttac tcacggcagc gcgttctgca
     8401 gtcagcaagc aagttacgtc agagtgggcg tgtggctcac cgttgtgaag gagatacacg
     8461 cagacatttc ccgcgcctga ctgagagagc gcaggaaccg gaaccacaac cagttcgtga
     8521 aaccagacct gtgcgcaatt tctatgtcgg cactaacgat ccccgtgtga ttttgtgcct
     8581 gacccgccag gcggaagaac tggagtccag gggcttatac cgtcgtgctg caaccgtgtg
     8641 gatggcggca ttccgtgaaa gccactccca gccagaacga aacaattttc tggcgcgtcg
     8701 tgagcggtgc ttacggaaaa gcagcaagcg cgctgcatcg ggtgaagagt ggtatctgtc
     8761 agggaattac gtgggggctt aatgagtaat aaatattgcc aggcgctggt ggaactgcgg
     8821 aacaaaccag cccatgaact gaaggaagtg ggcgatcagt ggcgcacgcc ggacaacatt
     8881 ttctggggaa ttaacaccct gtttggcccg tttgttctgg atctgttcac tgacggtgat
     8941 aacgccaaat gtgccgcgta ttacacggcg gaagacaacg cgctggcgca tgactggtca
     9001 gaacgtcttg cggagcttaa aggtgctgcc tttggtaatc ccccatacag ccgcgccagt
     9061 cagcatgagg ggcaatacat caccggcatg cgttacatca tgaaacatgc cagtgccatg
     9121 cgtgataagg gcgggcgcta tgttttcctg atcaaagctg ccaccagcga agtgtggtgg
     9181 ccggaagatg cagatcatat tgcttttatt cgcgggcgta ttggttttga actgcctgtc
     9241 tggtttatcc cgaaagacga gaagcaggta ccgacaggag cttttttcgc tggtgctatt
     9301 gctgtttttg acaagacctg gaagggaccg gcaatcagct acatcgggcg cgatgaactt
     9361 gaggcatgtg gtgaggcgtt tctggcgcag gttcgccagc aggcggaaaa actggtcagg
     9421 gagatggcgg catgacgacg ttaactcaat gccagcagca ggtgctggat atgctgattt
     9481 cttatcagaa agaacgtggc ttcccgccaa ccaatcagga ggtggcaacc atgctgggat
     9541 accgttcggt gaatgcagcg gtggagcatc ttcgcgcact ggagaaaaaa ggcgtcatca
     9601 cgataaagcg tggcgtggcc cgggggataa cgcttcatac cgcggtgaag gacgacgaca
     9661 gcgaggcggt cgggattatc cgcgcactgc ttgccggtga ggaaaacgca aggctgcgtg
     9721 caacccactg gttacatgag agggacctga aagtatgaag ctgatcctgc cttttccgcc
     9781 cagcgtgaac acgtactggc gacaccccaa caaaggggcg tttgctggta agagcctgat
     9841 aagcgcggcg gggcgaaaat tccagagcgc ggcgtgcgca gcaatagttg agcagttacg
     9901 tcgtctgccg aaaccaacgt cggcacctgc ttcagtggag atcgtgttgt ttcctccgga
     9961 taaccggatc cgcgatctgg acaactataa caaggcgctg tttgacgccc tgacccacgc
    10021 gggtgtgtgg gaggacgaca gtcaggtgaa aagaatgctg gtggagtggg gaccggttat
    10081 cccggaaggg aaggtcgaga tcactatcag taagtatgag aaaacggcgg gtgcagccgc
    10141 ctgatcaaga ggagaaacga agtatgaata atctgatggt cattgatggt attgaagttc
    10201 gtcgtgatgc ttatggtcgt tacagcctga acgatctgca cagggctgct ggttctctgg
    10261 ataagcataa gcccgcattc tggctccgca atgagcaaac tgaacgctta ataagcgagt
    10321 tgcagatttg caactcggtc aatatagcgc cagttaatgt cattcgtggt ggaaataacc
    10381 agggaacgta tgtctgcaag gaactggtgt atgcctatgc aatgtggatc agcccgtcat
    10441 tccatctgaa ggtgatccgt actttcgaca tggtaaccag cgcaccggaa aaattatccg
    10501 gacaggctgc tgacaagatg caggctggtg tgattctgct ggactttatg cgccgggaat
    10561 taaacctgtc taactcttca gtgcttggtg cctgtcagaa actccaggag gctgttggct
    10621 taccgaatct ggcaccgcgc tatgccattg atgctcctgc tgacgcgcct gatggctcaa
    10681 gccgccccac gctgtcactg agtgcactgc tgaagcagta tggtatccgc ctgacagcta
    10741 atcaggcata tcaccagatg gtgaagctgg ggatcgtcga gcagcgcgaa cgatacagcc
    10801 gtaccgcgat taacaacatc aaaaaattct ggtcgctgac agcgaaaggc tgcatgttcg
    10861 gcaagaatat caccagtccc gcaaatccgc gcgagacgca gccgcatttc ttcgaatccc
    10921 gattccctga gctgttaaag ctgctcgata ccgttcattg aggtgaccgt gagagcacta
    10981 ctgacccctg aaattgcccc gcgtatgggg atcgtattgt tcaggccagg ttcagagttg
    11041 atgcccctgt ttatgcaggg gcgtgtcctg ctggagcctg agccggaacg ttattcatct
    11101 ttcgccagtg gtgcagttcc ggcggcatca caaccgctgg cggatgatcc tgccgttcgg
    11161 gccgtgttcc gcaatgaggc agtgatccgt cgtgctggtg gcgtggaatg tcttgaaagc
    11221 tggttacttc gtgaaaaagg ctgccagtgg cctcattccg actggcacag cgagaacatg
    11281 accacaatgc gacacgctcc gggcgcaatc cgtctgtgct ggcactgcga taaccagctg
    11341 cgcgatcagt tcacggaacg gctggaatca atggcaacgg ataactgtgc ccgctgggtg
    11401 ttgtctgttg tgcgtcggga tctcggtttt gatgacagtc acgttgtgac aatgccggaa
    11461 ctgtgctggt ggctgattcg taatgatctg gcggatgcct taccggaaag tgcagcccgt
    11521 aaggcactga gattaccgaa gcctgttgtg ccgtctgtta cccgggaaag tgaccttgtg
    11581 ccttcggttc ctgccaccag catcatccag gataaggcga aaaaggtgct ggcgctgaaa
    11641 gtggatccgg agtcgccgga gtcttttatg ttacgcccaa aacgtcgccg ctgggttaat
    11701 gaaaagtaca cgcgctgggt taagacacag ccgtgtgcat gttgtggaaa gcccgctgat
    11761 gatccccacc acctgatagg tcacggtcag ggtggaatgg gaacaaaagc gcatgacctt
    11821 tttgtgttgc ctttgtgcag aaagcatcac gacgagctgc atgcggatac cgtggcattt
    11881 gaagagaagt atggctccca gctggagctg atatttcgtt ttatcgatcg tgcgctggca
    11941 attggcgtgc tggcctgatt ttgtggagaa agttgatgcg tgatatgtat gaagtattgg
    12001 accgctgggg tgcatgggct gcagcagata acagtggtgt ggactggcag cctgttgctg
    12061 cagggtttaa aggtttacta cctcatggaa agaaaacacg ccaacaatgc gatgatgatg
    12121 aaggaatcat gattgacagc tgtgttgcgc gattgcggaa atataagccc gaagagtatg
    12181 agttggttat tgctcatttt gttatcggca tctcactaag agctattgca aagaagcaga
    12241 agtgttctga tgggacaata agaaaagagt tgcaaacagc tcttggtttt ctggatggtg
    12301 tgctttcaat gttgtaatat tagggggaat tacccccctt tttttctctg ttgctttaat
    12361 aaaattttaa tattttgtct gattatgatg aggcaatgta ataaaagaaa taccgttagt
    12421 attgcaagcc atacgcaaaa taagcatgca tataaattag ttgaaagtcc aatagtgaat
    12481 tgtgcaattg ctgttgtgat agaacataat attgatgtat taataaatga ggataaattg
    12541 tctaaag
//
LOCUS       DAFGPF010000138        12498 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFGPF010000138 DAFGPF010000000
VERSION     DAFGPF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12498
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.138"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            312..518
                     /locus_tag="LSX49_004391"
     CDS             312..518
                     /locus_tag="LSX49_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7170706.1"
                     /translation="MTTPVSLMDDQMVDMAFITQLNGLTDKWFYRLIRDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARIAQPRP"
     gene            614..1216
                     /locus_tag="LSX49_004392"
     CDS             614..1216
                     /locus_tag="LSX49_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170707.1"
                     /translation="MKQQYQTRYELLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRATPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLEDWKENLKRK
                     SEKELEEWIINRQRQSAALTDLMDQYVLLAYRTTVDDNRN"
     gene            2417..3334
                     /locus_tag="LSX49_004393"
     CDS             2417..3334
                     /locus_tag="LSX49_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170708.1"
                     /translation="MVQKILSDKVMNERTNAYYSYYLGERNISVLPLNVYDPPERFIA
                     YIKKNRENLNITLSDFELEQIISGMRLKALAFLVPLEKISWIAGSERACLFSWYLLMQ
                     FIQNNRAKISADLLQKNKLYLKEEYLEGNAFPSDSSTQFRQILRVLDILSDKNLRDEW
                     IIQTKDRWIRAFKSKSPFSYLLPENEHECIWTWNYLKGKNIALEKLASFPGSADIYHA
                     IHLSFDIWVTCPLTSPDDIKNFRNSFNKAKAQRKYKKMQEDKVNVQFFLDAETRAQLK
                     ELSRVRRLSTGEMLHDLIVEEYKRYRHSR"
     gene            3419..4291
                     /locus_tag="LSX49_004394"
     CDS             3419..4291
                     /locus_tag="LSX49_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HBL7170709.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMVITDLPGVGESRNRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCIASVARTVLRAVRDT
                     VVSVARAVWNWIFF"
     gene            4664..7510
                     /gene="ag43"
                     /locus_tag="LSX49_004395"
     CDS             4664..7510
                     /gene="ag43"
                     /locus_tag="LSX49_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HBL7170710.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAA
                     VTSVPALAADTVVQAGETVNDGTLTNHDNQIVLGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATGTVINEKGWQAVKSGAMATDTVVNTGAEGGPDADNGDTGQFVRGNAVRTTINK
                     NGRQIVAAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQ
                     IVKEGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAATVTGSNRLGNFTVE
                     NGNADGVVLESGGRLDVLEGHSAQNTLVDDGGILAVSAGGKATDVTMTSGGALIADSG
                     ATVEGTNASGKFSIDGISGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGN
                     LSGRTQLSKGASMVLNGDVVSTGDIVNAGEIRFDNQTTPDAALSRAVAKGDSPVTFHK
                     LTTSNLTGQGGTINMRVRLDGSNTSDQLVINGGQATGKTWLAFTNVGNSNLGVATSGQ
                     GIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTS
                     MLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSY
                     GFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNL
                     VHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQL
                     QYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMSFGEGTSSRDTLRDSAK
                     HSVSELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARI
                     RENITLGVQGGYAHSVSGSSAEGYNGQATLNVTF"
     gene            7581..7739
                     /locus_tag="LSX49_004396"
     CDS             7581..7739
                     /locus_tag="LSX49_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HBL7170711.1"
                     /translation="MPGCTSRLLPEGPFSREQAVAVKTAYRNVFTEDDQGTYSRLVIR
                     NAEGQLRW"
     gene            7894..8712
                     /locus_tag="LSX49_004397"
     CDS             7894..8712
                     /locus_tag="LSX49_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBL7170712.1"
                     /translation="MRLASRFGYTNQIRRDRPLTHEELMHYVPSIFGEDRHTSRSKRY
                     AYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSPGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPTRQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIHNIDTDIKLNRALWVMAETLLESLR"
     gene            9054..9527
                     /locus_tag="LSX49_004398"
     CDS             9054..9527
                     /locus_tag="LSX49_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBL7170713.1"
                     /translation="MKTLSQNTTSSACAPETDLQKLVATPVPDERRISFWPQHFGLIP
                     QWVTLEPRIFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRIID"
     gene            9543..10019
                     /locus_tag="LSX49_004399"
     CDS             9543..10019
                     /locus_tag="LSX49_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HBL7170714.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEYGLL"
     gene            10082..10303
                     /locus_tag="LSX49_004400"
     CDS             10082..10303
                     /locus_tag="LSX49_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBL7170715.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            10466..10834
                     /locus_tag="LSX49_004401"
     CDS             10466..10834
                     /locus_tag="LSX49_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HBL7170716.1"
                     /translation="MSDTLSGTTHPDDNDDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFRDADAYPLDQAFPLLMKQLKLMLTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPETKK"
     gene            10924..11301
                     /locus_tag="LSX49_004402"
     CDS             10924..11301
                     /locus_tag="LSX49_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HBL7170717.1"
                     /translation="MKTLPDTHVREVSCCPSPVTIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDLPGFSACTHSQLINSIDILRARRATG
                     LMIRDNYRTVNNITLGKHPEAKR"
     gene            11298..11786
                     /locus_tag="LSX49_004403"
     CDS             11298..11786
                     /locus_tag="LSX49_004403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170718.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDIDGVNLAELINMVCDNGYS
                     LRVVDESDRTSADCTPPFVALTGIRCSTAHITETDNAWLYSLSHQTSDFGESEWIHFT
                     GTGYLLRTDTWSYPVLRLKRLGLSKTFRRLVVTLIRCYGVSLIHLDASAGYLPGLPTF
                     DW"
     gene            11803..11979
                     /locus_tag="LSX49_004404"
     CDS             11803..11979
                     /locus_tag="LSX49_004404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HBL7170719.1"
                     /translation="MKSLTTETALDILITWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IAQAREGIRTLRQQ"
     gene            12079..12237
                     /locus_tag="LSX49_004405"
     CDS             12079..12237
                     /locus_tag="LSX49_004405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170720.1"
                     /translation="MMMSDTTLSRPEVVSGHTDVIYSTSVCHILAVRKSTLLPIDTII
                     RHQVSDIS"
BASE COUNT         3012 a         3304 c         3262 g         2920 t
ORIGIN      
        1 cccacaggtc acaggctgat ataccacaac cgccttcaaa aacaactctg caattatcag
       61 aacgctagtt ttccccttgt ctcacgaaag tcctccctcc tttatcgcgt gcgcgtgcgg
      121 aagcatcgtt tcgcaacaac cacccgacat accggtacgg ctcagccacc gcaatccccc
      181 cgtttatctc ctgacggtca cattcccgat tattttttac gtttctcccc ggttgttatg
      241 ccggtgaagg tggtgcgttg ttttcatcac caacgccggt tgagattaac aacatccgga
      301 ggaacattct catgaccacc ccagtttcac tgatggatga ccagatggtc gacatggcat
      361 ttatcactca actgaacggc ctgacagata agtggtttta caggctcatc agggatgggg
      421 cctttccggc tcccatcaag ctgggccgca gctcccgctg gctgaaaagt gaagtggaag
      481 cctggctaca ggcgcgtatt gcacagcccc gcccgtaatt tctgaccgtt atccgttcac
      541 ccgcagcaga cgtaatcccc ggcctgccgg cggcattctg ctgcctgtta tatcccccgt
      601 gaggaatatg aaaatgaaac aacagtatca gacccgttac gaactgctcc acgaaagcta
      661 ccagaaatgg ctgaccggct tcacccggca cgccgtatcc tggggcgtgt gtcatccgaa
      721 tatctactac ttccataatc tgacgcccgg gtgggtgtca ttcaatggtg aaaaaccgga
      781 gattgccatc gtaccccaga gcctgcaccg gctgatttat ggccctgaca aacgggccac
      841 gccgcccctg gatgatgatc tgatagtgaa tttatgcacc agtgaacatc tgctggttca
      901 tcatccgatg ctggaaggca ttctcctgtc tgaatgtgaa cgtctgaggc agcgttctct
      961 ggcaaataaa ctgattagcc tcttccgtca gtttggtggc acggagttgc gcctcaaact
     1021 ggtctggctt tgctggcttg atttaatgac cggaaacagc cttgaagact ggaaagagaa
     1081 cctgaaacgg aaatcagaaa aagagctgga ggaatggatc atcaaccgtc agaggcagag
     1141 cgcagcactg acggatctga tggatcagta cgtgctcctg gcataccgca caacggttga
     1201 cgataaccgc aactgatgcc ggttgcttcc ggaaggtgtg acaaaatacg gaaatgatga
     1261 tgctcccggc cccgcatgct cacctgcaga gcgtgttcgt cgtcatcata ctgagccatg
     1321 acgggcgtct taagggcatc ctgtcattgc tgagcaggca acaccaccag aggagccacg
     1381 gacagggatg ttctttacag cccgatgcac gccaggttct cagcagactg aatgtgcagg
     1441 tgcggttatt caccagaaat ggcatgctgc ggtacatacc catcctggtg acaatatgta
     1501 cgtggcgaca gcgatcccgg cactgtggaa gagactcact cagcctgcag gatattcttt
     1561 ccggcatccg ggaatgtccg cctgaatgca aacaggatga tatttgaatc cgtaatactg
     1621 ttctttcatc ataaataatt tatgcagata cagttaaccg tcacagtagc aggtttgttt
     1681 tcccgggaaa taatatccgt cagactgatg ccggaacata tctgaaacac gttatgatgt
     1741 tttgttatca gaaatgttgt atattcttat ccgtggcgac agtttaatgc cctctggtat
     1801 cacctgataa tgcatatcct gcgatgattc gttatattta cgggacacgc ctcttttcat
     1861 tgtgctcctt ttcagacttc attttccgta agtgttcccc ggcataaagg aggtaccttt
     1921 ctggcgttta taactctctt tatcggtgac gccggtaata cagggaatac cacaccgaca
     1981 aacgaggtat taacagacga tatttcagtg tccataattt ttctgtccgg ttaaataacg
     2041 tcagtctgct gccctctgac tgtaatcatc aaagccggaa tgcataccgg gttacaacgt
     2101 aaaaaaagtg atgctggccc ccggtgcagc tggcgggcga aacatgttta cctttcaata
     2161 ccccctgtct gcagtctcca ctcttccatc ctcttaagct acgtcggcca catgagtgca
     2221 cttccatgat aacaggtatt cctgtcagca taacgaagcc ggttaccttc ccttcctcct
     2281 gcatttcctg tcagaatgac tgtacagcgc gcagattgcc tttttattga ccaccttaat
     2341 atactattat aaacttcttt ttatcatgtt attatcacct tattatgttt aatttttaag
     2401 caaccggaga aagaggatgg ttcagaaaat tttgtcggat aaggttatga atgaaagaac
     2461 aaatgcgtat tactcttatt atcttggaga gcgtaatatc tccgtactgc cccttaatgt
     2521 ttatgatccc ccggaacgtt ttatcgctta cataaaaaaa aacagagaaa atctgaacat
     2581 cacactttca gattttgaac ttgaacaaat aatttctggt atgcgtctga aggccctggc
     2641 cttcctggtc cccctggaaa aaatatcctg gatcgcgggc agtgaacgcg catgcttatt
     2701 ttcctggtat ctgttgatgc agtttatcca gaataacagg gcaaaaataa gcgcagactt
     2761 gcttcaaaag aataaactgt atcttaaaga agagtatctg gaagggaatg ccttcccgtc
     2821 ggactcatcg acacagttca gacaaatact cagagttctc gatattcttt ctgataagaa
     2881 tttgcgggat gagtggataa tccagaccaa agacagatgg atacgggcat ttaaatcaaa
     2941 gagtcctttc agttacctcc tcccggagaa cgaacatgaa tgcatatgga catggaatta
     3001 tttgaaggga aaaaatattg cactggaaaa actggccagt tttcctggtt ctgctgatat
     3061 ttaccacgca atccaccttt catttgacat atgggttacc tgtccactca cctcacctga
     3121 cgatataaaa aatttcagaa acagtttcaa taaggccaag gcgcagcgca agtacaaaaa
     3181 aatgcaggaa gataaagtca atgtacagtt ttttcttgac gcagaaacca gggcgcagct
     3241 caaagaatta tcgagggtca gaagactcag taccggcgaa atgctgcatg acctgattgt
     3301 tgaagagtat aaaaggtacc gacattccag ataatttcag acatatatta tctccgtgag
     3361 tcccccgcca cctttccggt gtgcgggggt tttgtctttt ttcaccggga atacatgtat
     3421 gaatccgtct gatgccattg aggcaattga aaaaccgctc tcctccctgc cttactcgct
     3481 ttcccgtcac atcctggaac atctgcgcaa actcaccagt cacgaacccg tgattggcat
     3541 tatgggtaaa agcggggccg gtaaatcctc actctgtaat gcactgtttc agggggaggt
     3601 caccccggtc agtgatgttc acgccggcac ccgggaagta cggcgcttcc gtctgagtgg
     3661 ccatggtcac agcatggtta tcactgacct gcccggggtg ggcgagagcc ggaacaggga
     3721 tgcagagtat gaagccctgt accgtgacat tctgcctgaa cttgacctgg tactgtggct
     3781 gattaaagcc gatgaccgtg ccctgtctgt ggatgagtat ttctggcgac acatcctgca
     3841 ccggggacat cagcaggtgc tgtttgtggt gacgcaggcc gacaaaacgg agccctgcca
     3901 tgaatgggat atggccggca ttcagccttc tcccgcacag gcacagaaca ttcgggagaa
     3961 aacggaggcg gtattccgtc tgttccggcc cgtacatccg gttgtggccg tatcggcccg
     4021 caccggctgg gaactggata cgctggtcag tgcgctcatg acagcacttc ccgaccatgc
     4081 cgccagtccc ctgatgaccc gcctgcagga cgagctgcgc acggaatctg tccggtctca
     4141 ggcccgtgaa cagtttaccg gtgcggtgga ccggatattt gacacggcgg agagcgtctg
     4201 tattgcctct gttgcacgca cggttctgcg tgccgtccgt gacacggtgg tctctgttgc
     4261 ccgcgctgta tggaactgga ttttcttctg aacactctgc caggggaaat gcctgattac
     4321 attgcgttaa ccaactgaaa acatgataca aacactccat ccccctcctg tttctcttgc
     4381 gtgactgctc tgctgttaat agaataaaac gatcgataaa acaggtatcg atcgttacca
     4441 tcgatcgttt atagtggtta atggtctgcg aaaaggcagc tgaatctctt catcatgcag
     4501 aacggaattg cacacaacgg actgatactt ctctggcgga tgagagaggg gaagcattta
     4561 tgtccgggaa aaaccacttt atctgaccat gctgttttgt acctgccggt atccactttt
     4621 gtgggtaccg gcttttttat tcaccctctg taaggaaaag ctgatgaaac gacatctgaa
     4681 caccagctac aggctggtat ggaatcacat tacgggcacc ctggtggtgg cctccgaact
     4741 ggcccgctca cggggaaaac gcgccggtgt ggcggttgca ctgtctcttg ctgctgtcac
     4801 atcagtcccg gcactggctg ctgacacggt tgtacaggcg ggagaaaccg tgaacgacgg
     4861 aacactgaca aatcatgaca accagattgt cctcggtacg gccaacggaa tgaccatcag
     4921 taccgggctg gagtatgggc cggataacga ggccaatacc ggcggacaat ggatacaaaa
     4981 tggcggtatc gccaacaaca ctactgtcac cggtggtggt cttcagagag tgaatgccgg
     5041 aggaagcgtt tcagacacgg ttatcagtgc cggaggagga cagagccttc aggggcaggc
     5101 agtgaatacc actctgaacg gcggtgagca gtgggtacat gaaggcggga ttgcaacggg
     5161 taccgtcatt aatgagaagg gctggcaggc cgtcaaatcc ggcgcaatgg caaccgacac
     5221 ggttgtgaat accggcgcgg aagggggacc agatgcagac aatggtgata ccgggcagtt
     5281 tgttcgcgga aatgccgtac gtaccaccat caataaaaat ggtcgtcaga ttgtggctgc
     5341 tgaaggaaca gcaaatacca ctgtggttta tgccggcggc gaccagacgg tacacgggca
     5401 tgcgctggat accacactga atggcggtta ccagtatgtg cacaacggag gcacagcctc
     5461 tgacacggtt gtaaacagtg acggctggca gattgtcaag gaaggtggtc tggcggattt
     5521 caccaccgtt aaccagaaag gcaaactgca ggtgaacgcc ggtggtacag ccacgaatgt
     5581 caccctgaag cagggaggcg cactggtcac cagtacggcg gcaaccgtca ccggcagcaa
     5641 ccgtctgggc aatttcactg tggaaaacgg taatgctgac ggtgttgttc tggagtccgg
     5701 tggtcgcctg gatgtactgg aaggccattc agcgcagaat accctggtgg atgacggcgg
     5761 tatcctggca gtgtctgccg gtggtaaggc aacagatgtc accatgacat ccggtggtgc
     5821 cctgatagca gacagtggtg ccactgttga ggggaccaat gccagcggta agttcagtat
     5881 tgatggtatc tccggtcagg ccagcggcct gctgctggaa aatggcggca gctttacggt
     5941 taatgccgga ggacaggctg gcaacaccac tgtcggacat cgtggaacac tgacgctggc
     6001 tgccggggga aatctgagtg gcagaacaca gctcagtaaa ggtgccagca tggtactgaa
     6061 tggtgatgtg gtcagtaccg gcgatattgt taacgcaggg gagattcgct ttgataatca
     6121 gacgacaccg gatgccgcgc tgagccgtgc tgttgcaaaa ggcgactccc cggtaacgtt
     6181 ccataaactg accaccagta acctcaccgg tcagggtggc accatcaata tgcgtgttcg
     6241 ccttgatggc agcaatacct ctgaccagct ggtgattaat ggtggtcagg caaccggcaa
     6301 aacctggctt gcgtttacaa atgtcggaaa cagtaacctt ggggtggcaa cctccggaca
     6361 gggtatccgg gttgtggatg cacagaatgg cgccaccaca gaagaaggtg cgtttgccct
     6421 gagtcgcccg cttcaggccg gcgcctttaa ctacaccctg aaccgtgaca gcgatgaaga
     6481 ctggtacctg cgcagtgaaa atgcttatcg tgctgaagtc cccctgtata catccatgct
     6541 gacacaggca atggactatg accggattct ggcaggctcc cgcagccatc agaccggtgt
     6601 aaacggtgaa aataacagcg tccgtctcag cattcagggc ggtcatctcg gtcacgataa
     6661 caacggcggt attgcccgtg gagccacgcc ggaaagcagc ggcagctatg gcttcgtccg
     6721 tctggagggt gacctgctca gaacagaggt tgccggtatg tctctgacga caggggtgta
     6781 tggtgccgca ggccattctt ccgttgatgt taaggatgat gacggctccc gcgccggcac
     6841 ggtccgggat gatgccggca gtctgggcgg atacctgaat ctggtacaca catcctccgg
     6901 cctgtgggct gacattgtgg cccagggaac ccgtcacagc atgaaagcgt catcggacaa
     6961 taacgacttc cgcgcccggg gctggggctg gctgggctca ctggaaaccg gtctgccctt
     7021 cagtatcact gacaatctga tgctggagcc acaactgcag tacacctggc agggactctc
     7081 cctggatgac ggccaggata acgccggtta tgtgaagttc gggcatggca gtgcacaaca
     7141 tgtgcgtgcc ggtttccgtc tgggcagcca caacgatatg agctttggtg aaggcacctc
     7201 atcccgtgac accctgcgcg acagtgcaaa acacagtgtg agtgaactgc cggtgaactg
     7261 gtgggtacag ccttctgtta tccgcacctt cagctcccgg ggtgacatga gcatggggac
     7321 agccgcagcc ggcagtaaca tgacgttctc accgtcccgg aatggcacgt cactggacct
     7381 gcaggccgga ctggaagccc gtatccggga aaatatcacc ctgggcgttc agggcggtta
     7441 tgcccacagc gtcagcggca gcagcgctga aggttataac ggtcaggcca cgctgaatgt
     7501 gactttctga taatcaggtc actctccttc aggccccggt catcatgacc ggggcttttt
     7561 actttcaggg agcaacagat atgccgggtt gtacatcacg tttattgccc gaaggccctt
     7621 tctcacgcga acaggctgtt gccgtcaaaa cagcttaccg caatgtgttt actgaagatg
     7681 accagggaac atattcccgg ctggttatcc gtaatgctga aggtcagttg cgctggtgat
     7741 gccggaacac agcttaatac tcagctcgcc agttaagggc ttctcagaca ataaacgtca
     7801 ttcatttcat ctgtcaggcc gcgtcttctc cgggagacgt ggctttttca tttattacac
     7861 cagtaaatct taaccaccga taaggagcaa attatgcgac tagccagtcg ttttggttat
     7921 acgaaccaga tacgccgtga ccgtccgctg acacacgaag aactgatgca ctatgttccc
     7981 agtattttcg gtgaagaccg gcatacttcc cgcagtaaac gatatgcgta cattcccacc
     8041 atcaccgtac tggaaagcct gcagcgggaa ggctttcagc cattcttcgc ctgccagacc
     8101 cgtgtgcgcg acccgggccg ccggggatac acaaaacaca tgctgcgtct gcggcgggcc
     8161 ggagagataa acggagaaca tgtccctgaa atcattctgc tcaactccca tgacggtacc
     8221 tccagctacc agatgctgcc gggttacttc aggttcgtct gtcagaacgg atgcgtctgt
     8281 ggtcagtctc cgggggaagt gcgtgttccg catcggggaa atgtggtgga cagagtcatt
     8341 gaaggggctt acgaggtggt gggcgtgttt gaccggattg aggaaaagcg tgatgccatg
     8401 cagtcgctgg tcctgccgcc accgacacgc caggcgctgg cacaggcggc actgacttac
     8461 cgttatggtg acgaacatca gccagtcacc accgctgaca ttctgacacc acgacgccgg
     8521 gaggattacg gtaaagacct gtggagcgca tatcagacca tccaggagaa tatgctgaaa
     8581 ggcggaattt ccggccgcag tgcaaaagga aaacgtatcc acacccgtgc cattcacaac
     8641 atcgacaccg atattaagct caaccgcgca ttgtgggtaa tggcagaaac gctgctggag
     8701 agcctgcgct gatgcagcat gtccctgaag gcgtgattca ggcaccagaa tcacccgacg
     8761 ccccggaggc gctgccgggg tgtcgttcca tttctgatga tgacctgtgc gcctggtgta
     8821 cccgtctgct ttaccgtccc ggagaaatca gtctgtgcag actgagtata caggcaatgg
     8881 catctggcca tccgtctgtg accggaacgg ttacgcgtac ggctgtccgg aatttcagcc
     8941 gaatatcatt catccctgat attaccgggt catcacggtc agtgatgaac gtgatgttgc
     9001 cagctcccga cctttactcc ctctcattta ttcacattac aaggatttca tacatgaaaa
     9061 cattgtctca gaacaccacc tcttcggcct gtgcaccgga gactgacctg caaaaactgg
     9121 tagccactcc cgtccctgat gaacggcgca tcagcttctg gccgcagcac tttggcctca
     9181 ttccacagtg ggtgaccctg gagccccgta tcttcggctg gatggaccgt ctgtgtgaag
     9241 actactgcgg tggtatctgg aatctgtaca ccctgaacaa cggcggggca tttatggcac
     9301 ccgaaccgga tgacgatgat gacgaaacat gggtactgtt caatgccatg aacggtaacc
     9361 gcgctgaaat gagcccggaa gccgccggca ttgctgcctg tctgatgacg tacagtcatc
     9421 atgcctgtcg tacggagtgt tatgccatga cggtccatta ttaccggctg cgggattacg
     9481 ccctgcagca tccggaatgc agcgccatta tgcgcatcat cgactgaatg gagagaagta
     9541 caatgcaaca gctttccttt ctgcccggag agatgacgcc cggcgagcgc agcctcattc
     9601 aacgggccct gaaaaccctg gaccgccatc ttcatgaacc cggcgtggcc ttcacctcca
     9661 cccgtgcggc acgagaatgg ctgattctga acatggcggg actggagcgt gaagagttcc
     9721 gggtgctgta tctgaacaac cagaatcagc tgattgccgg tgaaaccctc ttcaccggca
     9781 ccatcaaccg cacggaagtc catccccggg aagtgattaa acgcgccctg tatcacaatg
     9841 ccgctgctgt ggtgctggca cacaatcacc cgtccggtga agtcacaccc agcaaggcag
     9901 accgccttat cacggaacgt ctggtacagg cactgggcct ggtggatatc cgggtgccgg
     9961 accatctgat agtcggtggc agccaggttt tctcctttgc cgaatatggt ctgctttaac
    10021 ccgtcacaac cacatcacac ctgttttcac ttttatcttc tgtcttcaga ggtatcccac
    10081 tatgaaaatc atcacccgtg gcgaagccat gcgtattcac cgtcagcatc cggcatcccg
    10141 tctttttccg ttctgtaccg gcaaataccg ctggcacggc agtgctgaag cgtataccgg
    10201 tcgtgaagtg caggatattc ccggtgtgct ggccgtgttt gcagaacgcc gtaaggacag
    10261 ttttggtccg tatgtccggc tgatgagcgt caccctgaac tgatgttccg tcacccggaa
    10321 aacgagtacg actggcagag ctcagacgcc gctgtggatg aggtcctgct catcaacgaa
    10381 tacaccttta ccgaagccgg tctgcgcgcc ggctgacccg tcatcgttaa actatcattc
    10441 accgattttc tgtgaggatt ttatcgtgtc agacacactt tccgggacaa cgcatcccga
    10501 tgacaatgac gaccatccct ggtggggact accctgcaca gtgacgccct gtttcggcgc
    10561 ccgtctggtg caggagggta accggttgca ttaccttgcc gaccgtgccg gtatcagagg
    10621 ccggttcaga gatgcggatg cgtaccctct ggaccaggcc tttccgctgc tgatgaaaca
    10681 actgaaatta atgctcacca gtggtgaact gaatccccgc catcagcata ccgtgacact
    10741 gtatgcgaag gggctgacct gtgaagccga caccctcggc tcctgtggtt acgtttatct
    10801 ggctgtttat ccgacacctg aaacgaaaaa gtaaaccacc agaataacct tctgctccgg
    10861 cctggtgttt tcaccacgcc actgtcccat tttttatctc tgcatatcag gaaaatcttc
    10921 agtatgaaaa cattacccga cacgcatgta cgggaggtat cgtgctgccc gtctccagtc
    10981 accatctggc agacactgct cacccgactg ctggaccagc actacggcct tacgctgaat
    11041 gacacaccgt tcgctgatga acgtgtgatt gagcagcata ttgaggcagg catttcactg
    11101 tgtgatgcag tgaactttct cgtggaaaaa tacgcactgg tacgtaccga cctgccggga
    11161 ttcagcgcct gtacccactc tcagttaata aacagcatcg atatcctccg ggctcgccgg
    11221 gcaacaggcc tgatgatccg cgacaattac agaacggtaa ataacattac cctggggaag
    11281 catccggagg cgaaacgatg aaactggccc tgacgctgga agccgacagc gttaacgtgc
    11341 aggcgctgaa catggggcgc attgtcgttg acattgatgg tgttaatctc gctgaactga
    11401 ttaacatggt ctgcgataac ggctactccc ttcgtgttgt tgatgaatct gaccggacct
    11461 cagcagactg cacgccacca tttgttgccc ttaccggcat acgctgcagt accgcacata
    11521 tcacggaaac ggacaacgcc tggctgtact cgctgtcaca ccagaccagt gacttcggtg
    11581 aatcagaatg gattcatttt accggtaccg gttatctgtt acgtaccgat acgtggtcat
    11641 acccggttct gcggcttaag cgcctggggc tgtcaaaaac gttccgtcgt ctggtcgtca
    11701 cactcatccg gtgttatggt gtcagtctca ttcatctgga tgccagtgcc ggatatctgc
    11761 cgggtttacc cactttcgac tggtaatccg gaaattcaca acatgaaatc attaaccacg
    11821 gaaacagcgc tggatattct gattacgtgg ctgcaggaca atatcgactg cgaatcggga
    11881 attatcttcg acaacgatga ggataaaaca gattcggcag cactgttgcc ctgtatcgca
    11941 caggccaggg agggtatccg taccctgcgc caacagtaac ttttgtacca gaaccagtga
    12001 agatcactca cccgatttca cttccctgac gtcagcctga acacggctgg cattttcatt
    12061 tataaacaga aaggaaaaat gatgatgtca gataccacac tctcccgccc ggaggtggtc
    12121 agcgggcata cggacgttat ctattccacc tcagtctgcc acattctggc tgtacgaaag
    12181 agtacactgt tgccaatcga cacaattatc cggcatcaag taagcgatat cagttaaccg
    12241 atatagatgg ggaagatgct tttatccgga ttggttctat cgcgatggtg cgagtaccac
    12301 ttgatgcaat ggagcctgtc gaggaagatg acgagtaaca gagctcggta tctcaatcag
    12361 gacctgattg tcctggttcg atgccgaaaa ccagtgattt ttcgtgttgg tatctgtgtt
    12421 ggtataggat ggtgttgttt attattaaca attttaaatc atgaggttaa atcgcatgtt
    12481 tgagtccggc cttcgcac
//
LOCUS       DAFGPF010000139        11734 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFGPF010000139 DAFGPF010000000
VERSION     DAFGPF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11734
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.139"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            96..1874
                     /locus_tag="LSX49_004406"
     CDS             96..1874
                     /locus_tag="LSX49_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HBL7170721.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAG
                     TGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTP
                     VILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
                     IFATMIDNMDQGVLVVDADNRVQFVNQTALKTLGVVQNNIIGKPVRFRPLTFESNFTH
                     GHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGEC
                     RVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPE
                     QLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAR
                     EILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQED
                     IELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGE
                     VIDSTLLPPNLLNNGTTEQSDVTEASEAHLSLDDAGGTALEEMEKQMIREALSRHNSK
                     KEVADELGIGIATLYRKIKKYELLNT"
     gene            complement(1913..2392)
                     /gene="xdhC"
                     /locus_tag="LSX49_004407"
     CDS             complement(1913..2392)
                     /gene="xdhC"
                     /locus_tag="LSX49_004407"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HBL7170722.1"
                     /translation="MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLFLAAWAEGKEIRTLEGEAKGGKLSHVQLAYAKSGAVQ
                     CGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK"
     gene            complement(2389..3267)
                     /gene="xdhB"
                     /locus_tag="LSX49_004408"
     CDS             complement(2389..3267)
                     /gene="xdhB"
                     /locus_tag="LSX49_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HBL7170723.1"
                     /translation="MFDFASYHRAATLADAINLLTDNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGALRIGSATTFTQLIEDPVTQRHLPALCAAAASIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            complement(3278..5575)
                     /gene="xdhA"
                     /locus_tag="LSX49_004409"
     CDS             complement(3278..5575)
                     /gene="xdhA"
                     /locus_tag="LSX49_004409"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HBL7170724.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPEIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAVQLVSIEWQELPVITSSEAALAEDAAPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALDIPWSCVRVIKPFIGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            5989..6744
                     /locus_tag="LSX49_004410"
     CDS             5989..6744
                     /locus_tag="LSX49_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311765.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL7170725.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSSTRKSTAKSTT
                     KTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYA
                     AGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGST
                     DAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            6823..6896
                     /locus_tag="LSX49_004411"
     tRNA            6823..6896
                     /locus_tag="LSX49_004411"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6855..6857,aa:Gly,seq:ccc)
     gene            complement(7213..8442)
                     /locus_tag="LSX49_004412"
     CDS             complement(7213..8442)
                     /locus_tag="LSX49_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HBL7170726.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGN
                     LITLIVGILCVSVMFFS"
     gene            8697..9878
                     /locus_tag="LSX49_004413"
     CDS             8697..9878
                     /locus_tag="LSX49_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBL7170727.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVP
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVITQSNGQTLVVDTDEQ
                     PRTDTSAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
     gene            10165..11001
                     /gene="kduI"
                     /locus_tag="LSX49_004414"
     CDS             10165..11001
                     /gene="kduI"
                     /locus_tag="LSX49_004414"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBL7170728.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDR
                     IIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRD
                     ALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            11031..>11734
                     /gene="kduD"
                     /locus_tag="LSX49_004415"
     CDS             11031..>11734
                     /gene="kduD"
                     /locus_tag="LSX49_004415"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HBL7170729.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIKQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPVVFLASSA"
BASE COUNT         3013 a         2726 c         2976 g         3019 t
ORIGIN      
        1 tcaaagccaa tttcgcctga gttaatatca tcatgatctg tgaaccatca acgtcttcaa
       61 tgatcgactt ttaagtaagt ctggaaggta aagctatgga gcttgcgact acgcagtcag
      121 tattgatgca aattcaacca acaattcagc gttttgccag aatgcttgcc agcgttttgc
      181 agcttgaggt tgagatcgtt gatgaaaact tgtgtcgcgt cgccggaacg ggcgcgtatg
      241 ggaagtttct tggccgccag ttgagcggca actcacgtct gctccgccac gtcctggaaa
      301 cgaaaactga aaaagttgtg acacagtctc gcttcgatcc cctttgtgaa ggttgcgata
      361 gtaaagaaaa ttgccgcgaa aaagcatttc tgggtacgcc agtcatttta caggatcgtt
      421 gtgttggggt gataagtttg attgccgtta cccacgagca acaagaacat atcagtgata
      481 atttacgcga attttccgat tacgttcgcc atatatccac catttttgtt tctaaacttc
      541 tggaggatca gggaccagga gataacatca gtaaaatatt cgcgaccatg atcgataata
      601 tggatcaggg cgtgttagtg gttgatgctg ataatcgggt tcagtttgtt aatcagacag
      661 ctttaaaaac actcggtgtt gtacaaaata atattattgg aaaacctgtt cgtttcagac
      721 cattaacatt tgagagtaat tttacccatg gtcatatgca acatattgtt tcgtgggatg
      781 ataaaagtga attaatcatt ggtcagttgc ataacatcca gggccgacaa ctatttttaa
      841 tggcgtttca ccaatcgcat accagttttt ctgtagcaaa tgcacctgat gaaccgcata
      901 ttgaacaatt ggttggcgag tgccgtgtta tgcggcaatt aaaacgactc attagccgta
      961 ttgcacccag cccatccagc gttatggtgg ttggtgaaag cggcacgggt aaagaagtcg
     1021 tcgcccgtgc aatccataag ttgagcggaa gacggaataa accctttatt gctatcaact
     1081 gtgccgcgat tccggaacag cttctggaga gcgaactgtt cggttatgtt aaaggcgcat
     1141 ttactggcgc ttctgccaac ggtaaaacag ggttgattca ggcggcgaat acgggcacgc
     1201 tgtttctcga tgaaattggt gatatgccat taatgttgca ggctaaatta ctgcgcgcta
     1261 ttgaggcgcg tgaaattctg ccgattggtg ccagtagccc aatacaagtc gacatccgca
     1321 tcatttctgc aactaatcag aatttggccc agttcattgc cgaaggtaaa ttccgcgaag
     1381 atctcttcta ccgacttaat gttatcccga taactcttcc accgctgcgt gaacgtcagg
     1441 aagatattga attactagtg cattactttt tacatctgca tacccgtcgt ctgggatcgg
     1501 tttatcctgg cattgctcct gatgtcgtcg aaatattgcg taagcatcgt tggcccggaa
     1561 acctgcgcga gttaagcaat ttgatggaat atctggttaa cgttgttcct tcaggtgaag
     1621 ttatcgacag cacgctattg ccgccaaatc tgctgaataa tggcacaacg gagcaaagtg
     1681 atgtaacaga ggccagtgag gcgcacctgt cactcgatga tgcgggcggc acggcgctgg
     1741 aagagatgga aaagcaaatg atccgcgagg cgctttcacg tcataacagc aagaaggaag
     1801 ttgctgatga actgggcatc ggcattgcta cgctctatcg caagattaag aaatatgagt
     1861 tgttaaacac ataacctctg agaatccggc ctgaattcag gccggatatc ttttactttg
     1921 ttttctcgca atccagaact gtatttacaa tcatctgata ccccgtgcag cgacaaagat
     1981 ttcccgccag tccacgacga atttccgtaa tggttaatgg cttctcgcgt ggtttcgcca
     2041 gcattgccgt ggtagccata atcaggcccg gcgtacaaaa cccgcattgc actgcaccag
     2101 atttcgcata agccagttgg acatgagaaa gtttaccgcc tttcgcttca ccttccagcg
     2161 tgcggatctc ttttccttca gcccaggccg caaggaataa gcaactgtct atcgcagtgc
     2221 cgtcgaccag caccgtacag gcaccacatt cacccacgca gcacccttgt ttgacactta
     2281 gcagtccttg ttcgcggagt aattccgaga gcggcgtgcc tggtgcggcg tgaagctgaa
     2341 aaggcatccc gttaatggtg cattcgatgg taattgtttc gctgtgattc attgcaattt
     2401 cccccccgcc gcggcgacgg cttcgctaat cacttttttg gtcatcgtct ggatgagatg
     2461 cagacgaaac tctttactgg cccgccatga cgaacgcggg gcgacatctt gcaggactga
     2521 ttcgctgatg gcttccagcg tttgcaggtt taatggcgca ttttgtgcag tctgttcggc
     2581 atgttggcag cgaatcggcg ttggcgcggc aacaccaaat gccaggcgta attcgctgaa
     2641 attgccgtta tccagtcggc aatgtgcggc gcagccaatt gttgaaatat ccattgcgtc
     2701 gcgcatggca tatttaaaat gcgcgctgcc cgcgtgttct ttcggctgtg gcggaaaatg
     2761 aaaggcgaca aggatttcgt catgctcaag agacactttg cccggcccgg tgtgaaagcc
     2821 attaatcggg acgaaacgaa caccgcgcgg ggagtggatc tccagtttcg cgtcataaat
     2881 tagcgttggc gtggcagaat ctgcgctggt ggcaccgttg caaatatttc cgccgtaggt
     2941 ggcgacatta cggatctgcg gcccggcgat tgatgcagcc gcagcacata acgccgggag
     3001 atgacgttga gttacaggat cttcaatgag ctgggtaaat gtcgttgcag agccgatacg
     3061 tagcgcgcca tcttccgcca gcgtaattcc ccgcagctcc gccagattat gaatatcaac
     3121 aatatggcga taacggtcat tgtgatggtg aagctgtatc agtacgtcag tgccaccggc
     3181 gagcagtttg gcctgcgggt tgtcagtcag caggttgatg gcatcggcaa gggttgctgc
     3241 gcgatggtaa gaagcaaaat caaacatgat gttatcctca aatcaatcct gccagatgga
     3301 attcttcata taatcgtttt ggcgttagcg gcagtgtatt gattgcaaca ccggtagcca
     3361 tcttcaccgc gttacgaata gcagcggcta caggaattat gggtggctca cccagtgact
     3421 tatgtccgta tgcggattgc ggctcattga tttcgacgaa cgcgctttcc agttgtggca
     3481 gatccggcat ggtcggcatt ttgtaatcca gcagattggg gttacggacc acgccgcttt
     3541 tcgcatcgat gatcatctct tcaaatagcg cccagccaat gcccatcccc attccgccgt
     3601 gtacctgacc ttctgccagc agcggattaa gaatatggcc cgaatcatga acgttgagga
     3661 tgcggttgat ggttacttta cacagtgcaa tatcgaccgt cagatcaaca aaggtacagc
     3721 caaacgccgg tgggttagtg gtggttttga tggagctttc ggcagagagc tgcccgccgc
     3781 gttcagggtg gtagaaagcg tccatcgcca aatcttttaa cgacattaac ggctcttccg
     3841 gtcgttcaac cagcacgata tggcctttta tcagggtcag attcatcgct gactgatgta
     3901 gcatgactgc ggcgtgagcg atgattttct cttttaataa cagtgccgca ctgcgcagcg
     3961 caggcgcggc aacatagctc tgacgtgagg caaatgcgcc ggggtcgaat ggtgtaacgt
     4021 cggtgtcttg tgtcgaaatt acgcggacat cgctgaccgg aactcccacg gtttctgcca
     4081 ccatttgcga gaacacggtg tcggcaccct ggccgatttc cgtcgcgccg ctttgcacgt
     4141 tgatggttcc atcctgattc atcaacaggc gcgcgcctgc tatttctacg ccgacaggcc
     4201 aggtgttaga ggtgtagcta aaacaggcga cgccaacgcc acgacgtaaa ttgccttgct
     4261 ggttctggca ctctgcacgg cgtttttccc attcaaagat tttccggcct ttttcaagac
     4321 actccggcaa ccctgcgctg taaatacgtt ttcccgtgag cggattagca tctccttcgc
     4381 gggcggcgtt gcgtaaacga atttcaacag gatcaatacc taacgctgtc gcggcatcat
     4441 caagcataga ctcaacggca aatacgactt gtggcgcgcc ataaccacgc atcgcaccag
     4501 ccgaggggag gttggtatag caggtctttg aactgtaagc gtaggcacaa cgaggataaa
     4561 ggtaagcgac tttattcccc ccagcagaag caatggagtg cccgtgagat gcataagcgc
     4621 cggtgttaga cagaacatcc agactataac ctttcaatgt tccgtcgcgg ttcacgccca
     4681 tttgcccgtc aatagtaaaa gcgtggcggg tacgggttgc gaggaaacac tcttcacggc
     4741 taagagaaac tttcaccgga atgccgccaa gtttgcttgt caggaatgcc gccattggct
     4801 cttccagtac atcctgttta ttaccaaaac cgccaccgat aaacggtttg atgactcgta
     4861 cgcatgacca gggaatatcc agcgcctgac caaccacgcg gcgaacaatg tgcgggatct
     4921 gggtgctgga aacgatggta attcgcgagt catcctccat ccatgccagc gatgtcacgc
     4981 tttccatatg acaatgttga ataacgggcg tctgatagtg cccctgtacc tggtagtcgg
     5041 cggcatcgat tgtttgttgg acattacccg tcgacatcgt gctttgtttc agtaaattgc
     5101 caccgttatg gattggtgca gcgtcttctg ccagcgccgc ttctgacgag gtgataacgg
     5161 gtaattcttg ccactcaatg ctgaccaatt gcaccgcttt ttctgccgtg agttcatcgc
     5221 gggctacgac gatggcaacg gcgtcaccat gatgacgaac atgacgcgtt agcagggcac
     5281 gatcggcagt atcgcgcttg ttttcgtcaa gtgtccaggc atgccctgcc gtggcgaatg
     5341 ggatttctgg cacatcttcc caggtaaaaa tcgccaggac gcccggcaaa ctcctggctt
     5401 gttcatcatt aatacttacg gcataaccat gtgcgatagg gctacgtaca tatttcgcgt
     5461 aacacatgcc cgccataaca taatcgtcag tatatcgtgc ccgcccggtg accttagcaa
     5521 tggcatcgac gcgcatgcat gattcacccg tagcggttgc ttcccgcgct tccatagaaa
     5581 tcccctcggt ttgaacattt ggttcttatg gcaaagattt agtcttagca ggcaagaatt
     5641 acgccagaaa cgactatatg cgtgagggga ggaaggaagt gtgatgacgt taaaaaaaca
     5701 cagatatgat acgaaacagg actctgaata gggacagtga tacgtatcaa tatgagtggc
     5761 gataaaatca atgtgataaa ttaggattat tacgcatcaa ggtgggaaat agggtaaaag
     5821 tcaggaaatt cgataccact acagcaaata ttttgctgat gatacttccc tttgccaaat
     5881 gaaattaacc tctttctcta ttacatcgtt tttccagaag caagagattg ggtatcaaga
     5941 ggctggctgc tatgatatgg cgtcttgttt tttaagcgag gaaagatttt gagtgcggga
     6001 cgcctgaata aaaaatctct gggtatcgtg atgttgttat cggttggact gcttttggcg
     6061 ggctgttcgg gtagcaaatc atccgataca ggaacgtatt ccggctccgt ttacaccgtg
     6121 aaacgggggg atacgctata tcgtatttcg cgcaccacgg gaaccagcgt aaaagaactg
     6181 gcgcgactga acggcatttc ccccccttac accattgaag taggtcagaa actaaaactg
     6241 ggtggggcga aaagtagcag tagtacacgt aaatcaaccg ccaaatccac gaccaaaacc
     6301 gcatcggtta caccgtcatc agcggtaccg aaatcttcct ggccgccagt agggcaacgt
     6361 tgttggttat ggccaacgac agggaaagtt atcatgccgt attcgacagc agatggcggc
     6421 aataaaggga ttgatatctc agctccacga ggtacaccta tttacgccgc gggtgcagga
     6481 aaggtggtgt atgtgggcaa ccagctgcgt ggctacggta atctcatcat gattaaacac
     6541 agtgaagatt acattacggc ttacgctcat aatgacacga tgctggtaaa taatgggcaa
     6601 agcgtgaagg ctgggcaaaa aatcgccact atggggagca ctgatgcggc atctgttcgc
     6661 ctgcatttcc agattcgtta ccgtgcaacg gcaattgatc cgctacgtta cttgccgcct
     6721 cagggcagca agccaaaatg ctgatggcga attaatcagc agtcagcagc gtggtacttg
     6781 ctaaggagag cgtaaggttt ataatgcctt acgcatctcg aagcgggcgt agttcaatgg
     6841 tagaacgaga gcttcccaag ctctatacga gggttcgatt cccttcgccc gctccaattt
     6901 atcttcacat catctacctg ccatttttgt tgtatctgat tttctatatt atcttaattc
     6961 aagcgcttca gacttttcgc aatcgccgta atacttcccc atttttttgt aaataaaaag
     7021 cgtttacgca atgcaatcgt catgtatctt aaatagtctt atttaagatg ttcagaactc
     7081 tttgtgtgtt taactggctg ataattatat aatattacga gagaagtgat agagcggaat
     7141 aataacaaat gaacattatg aaaactggga tggttcaaaa ttgaagcaat tttgaaccat
     7201 ccacaacgga tattagctaa agaacattac cgatacgcac aggataccca cgatcagggt
     7261 aatcagattt ccgatggaac gccagggttt aagcgccggg atgagatacg ttgacagcgt
     7321 aggcatgatg aaaagtatca tggcaatgag cgggccgctg atcgcgtaaa tcatcgaaat
     7381 cgcgttcggg ttaatgcaac aaacaatgaa ggtaatcagc gataccaaca taattgatag
     7441 tgcgcggtta aatgcacgac ttttctttac accaacctgc tgtaatgttg ttttgacgac
     7501 ctctgtggca ccttcaataa cgccaaagta cgtacccagg aatgatttcg acatcgcaac
     7561 tactgcgaca ataatcccgg aaattgacaa ccatgctggg gcgttcggca gcatagaaag
     7621 cgccgataaa atggtaaccc cttcttcttt agccgcttca atatacgaag gtggaataga
     7681 aagcaggcag ctaaagacaa agaacaatac acttatgcag atgatgagat aagcgacttt
     7741 cataattttt ttgcatttat ccatagcatg ttcgccatat ttttcacgtc tgtctatggc
     7801 aaacgtagaa ataatgggcg tatggctaaa agcgaaaacc atcacgggaa tcgatatcca
     7861 tatctggtga agggtattct gattgaactc tacctgggtt gttaatagat caggttgcca
     7921 actaccgacc aggtaaatag aaagaaataa gaaataggca atcaatggga ataccaaaaa
     7981 tcccattacc cgaatagtgg catggcgtcc catcagaaaa atgagattca ggattaatac
     8041 aacccccaga ctcactagca tacggatgcg aagatcaata accatatgct ttgccagctg
     8101 ttccgtaagt gagttggtaa ttgccactgc atatatcaac acgacgacaa aaaaggcgat
     8161 gaagtacagc gtggtaatca gattaccaat cttcttgcca tagtagtgtg ttaccgcgcc
     8221 cgttatccct tcacctgctg atgttttcga tgagaggatg aactggcata aggctttatg
     8281 tggccaatat gttaaaggcc aggcgaccag agcagtaata aacaggacca cagcccccgc
     8341 cgaacctaac tgaataggaa ggaagagcgt gcctgcacca acggctgtgc cgtagagtgc
     8401 gaaactccac agagtttctt cttttgacca aatattagac attatctgaa cgtatcatct
     8461 acaaattaaa caaaatggag ggcaatttac cataaaccag gttaagtatg ggagattaac
     8521 gccttatcta cctctctatt ggtgggttag tggttgcaaa ccttacgtgc cagttatgtc
     8581 tctgactact actcaggcgt atttcctttg tgataatggt cacttttttt aaacaattaa
     8641 gataactgta attaacaatc atttactatt gcactgttaa ttggtgcgag gttgtgatga
     8701 aagacgttgt gattgtcggg gcgttacgga cacctatcgg ctgctttcgt ggtgcgttag
     8761 cgggtcattc cgccgtggaa cttggcagcc tggtcgtcaa agcgttaata gaacgtaccg
     8821 gcgttcctgc atatgcggtg gatgaagtga ttcttggtca ggtgttgact gcaggggcag
     8881 ggcagaatcc ggcaagacaa tcggctatta aaggtggtct tcctaatagc gtttctgcaa
     8941 tcactattaa tgacgtttgt ggttccgggc ttaaagcact gcatctggct actcaggcga
     9001 tacagtgtgg cgaggctgat attgtcatcg ccggtggcca ggaaaacatg agccgcgcac
     9061 cacatgttct gactgatagc cgcaccggcg cacagcttgg caatagccag ttggttgata
     9121 gtcttgtgca tgatgggttg tgggatgcct tcaatgatta tcatattggt gtcaccgccg
     9181 aaaatctggc tcgcgaatat ggcatcagcc gtcagttgca ggatgcttac gcacttagct
     9241 cgcaacaaaa agcgcgagcg gcgattgacg ccggacgatt taaagatgag atcgtcccgg
     9301 taataaccca aagtaacggt cagacgttgg ttgttgatac cgatgaacag ccacgcactg
     9361 acaccagcgc agaaggctta gcccgtttaa atccttcatt tgatagtctc ggttctgtga
     9421 cagcgggtaa tgcatcatcc ataaacgatg gggcagctgc agtaatgatg atgagcgaag
     9481 ccaaagcacg agcgttgaat ttacccgtgc tggcccgcat ccgcgcattt gccagcgttg
     9541 gtgtggatcc ggcattgatg ggaattgcgc cggtgtatgc gacccgccgt tgcctggagc
     9601 gtgttggctg gcagttggct gatgtcgatc ttatcgaggc taatgaagcg tttgctgcac
     9661 aggcgctttc ggttggcaag atgcttgaat gggatgagcg tcgggtcaat gttaatggtg
     9721 gtgcgatcgc actcggtcac ccgataggcg cttccggttg ccgaatcctg gtttctcttg
     9781 ttcatgaaat ggtgaaacgt aatgcccgca aaggactggc aacgctttgt atcggcggag
     9841 gccagggtgt ggcattgacc attgaacgtg acgagtagct ctgcattacc tccttaccga
     9901 taaatatctg ccgtcattaa tctgttgaat aatgatggct ggtgagtcga catacctttt
     9961 cagggctccc tgatttttcc attctcatga catattcgtg atcgacactg cacttttttt
    10021 aatccttaac ttgaaaatga aacattgttt tatttttaat tgaaaaccct atcccatggg
    10081 catatcatcc cctcatagag aaaacgaaac agtgttttat tattgttttc tattttcacg
    10141 cttcactgat tatcggaggt tgatgtggac gtaagacaga gcatccacag cgcgcacgca
    10201 aaaacgctgg atacccaggg gctgcgcaat gaatttttgg ttgaaaaggt atttgtcgcc
    10261 gatgagtaca ccatggttta cagccacatt gaccgtatta ttgttggcgg cattatgccg
    10321 gtaactaaaa cggtttccgt tggcggggaa gttggtaaac aactcggcgt aagctatttc
    10381 cttgaacgtc gcgagttagg tgttatcaat attggcggtg ccggtacgat tactgtcgat
    10441 ggtcaatgct atgaaatcgg tcaccgcgac gccctgtatg ttggtaaagg tgcaaaagaa
    10501 gttgtctttg ccagtattga taccgccact ccggcgaagt tttattacaa ttgcgcaccc
    10561 gcgcatacga cgtatcccac caaaaaagtc acaccggacg aagtatctcc agtcacgtta
    10621 ggcgataacc tcaccagtaa ccgtcgcacg attaacaaat attttgtccc ggatgtgctg
    10681 gaaacctgcc aattgagtat ggggctgacg gagctggctc caggtaactt gtggaacacc
    10741 atgccgtgtc acacccacga gcgccggatg gaagtttatt tctatttcaa tatggatgat
    10801 gacgcctgcg ttttccacat gatggggcaa ccgcaagaaa cgcgtcacat tgtgatgcat
    10861 aacgagcagg cggtgatctc cccgagctgg tcgatccatt ccggcgtcgg aaccaaagct
    10921 tataccttta tctggggcat ggtcggtgaa aaccaggttt ttgatgatat ggaccatgtg
    10981 gccgttaaag atttgcgcta gttgtgggca taaacgaata aggtattgtt atgattttaa
    11041 gtgcattttc tctcgaaggt aaagttgcgg tcgtcactgg ttgtgatact gggctgggcc
    11101 aggggatggc gttggggctg gcgcaagcgg gctgtgacat tgttggcatt aacatcgttg
    11161 aaccgactga aaccatcaag caggtcacgg cgctggggcg tcgtttttta agcctgaccg
    11221 ccgatctgcg aaagattgat ggcattccag cactgctgga tcgcgcggta gcggagtttg
    11281 gtcatattga tatcctggtg aataacgccg gattgattcg ccgcgaagac gctctcgaat
    11341 tcagcgaaaa agactgggac gatgtcatga acctgaatat caagagcgta ttcttcatgt
    11401 ctcaggcagc ggcgaaacac tttatcgcgc aaggcaatgg cggcaagatt atcaatatcg
    11461 cgtcaatgct ctccttccag ggcgggatcc gtgtgccttc ttataccgca tcaaaaagcg
    11521 gtgtgatggg cgtgacgcga ttgatggcga acgaatgggc taaacacaac attaatgtta
    11581 atgcgatagc tccgggttac atggcgacca acaatactca acaactgcgg gcagatgaac
    11641 aacgtagcgc ggaaattctc gaccgcattc cagctggccg ttggggactg ccgagtgacc
    11701 tgatggggcc ggtggtgttc cttgcctcca gcgc
//
LOCUS       DAFGPF010000140        11470 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFGPF010000140 DAFGPF010000000
VERSION     DAFGPF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11470
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.140"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..781)
                     /locus_tag="LSX49_004416"
     CDS             complement(<1..781)
                     /locus_tag="LSX49_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL7170730.1"
                     /translation="MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGAN
                     VFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNA
                     GICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
                     QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVL
                     DHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLV"
     gene            1100..2377
                     /locus_tag="LSX49_004417"
     CDS             1100..2377
                     /locus_tag="LSX49_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170731.1"
                     /translation="MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSN
                     TEIGLIMSTFGIAAIIFYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVML
                     CIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFS
                     RFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVL
                     RISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPL
                     GGIITTYSKVKSPTRVVQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYAS
                     RGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGYWQDTLPAAEAYRNMWL
                     MGMAALGMVIIFTFLLFQKIRTADSAPAMASSK"
     gene            2404..3882
                     /locus_tag="LSX49_004418"
     CDS             2404..3882
                     /locus_tag="LSX49_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL7170732.1"
                     /translation="MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDAD
                     TAEHPDDDLWASLCFASHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLIS
                     WQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSED
                     ATVMEKFNIPRQMLFDVQMPGTILGHITPQAALATHFPAGLPVVCTTSDKPVEALGAG
                     LLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSW
                     LRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMI
                     GFDSSMDYAWIYRSILESVALTLKNNYDNMCHEMNHFAKHVIITGGGSNSDLFMQIFA
                     DVFNLPARRNAINGCASLGAAINTAVGLGLYPDYTTAVDKMVRVKDIFIPIESNAKRY
                     DAMNKGIFKDLTKHTDVILKKSYEVMHGELGNADSIQSWSNA"
     gene            4047..4967
                     /locus_tag="LSX49_004419"
     CDS             4047..4967
                     /locus_tag="LSX49_004419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001461526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HBL7170733.1"
                     /translation="MSTRVWVLGDAVVDLLPESQGRLLQCPGGAPANVAVGIARLGGK
                     SAFIGKVGDDPFGRFMYQTLSTENVDTRYMSLDPQHRTSIVAVGLDEQGERNFTFMVR
                     PSADLFLQPDDLPAFGPGEWLHLCSIALSAEPSRSTAFLAMEKIRQAGGNISFDPNIR
                     SDLWQSEALLRKYLDRALSLANIAKLSEEELLFISDESQVQQGAYSLVQRYPLTLLLI
                     TQGKNGVLVYFQGQFIHYPAKPVSVVDTTGAGDAFVAGLLAGLADSGIPTNTRQLERI
                     IAQAQICGALATTAKGAMTALPRQHDLPSQ"
     gene            5135..6652
                     /locus_tag="LSX49_004420"
     CDS             5135..6652
                     /locus_tag="LSX49_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003857084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HBL7170734.1"
                     /translation="MYKKTTLAVLIALLTGATTVHAQTDISSIESRLAALEQRLKNAE
                     SRAQAAEARAKTAELQVQKLAETQQQNQLTTQEVAQRTVQLEQKSAENSGFEFHGYAR
                     SGLLMNDAASSSKSGPYLTPAGETGGAVGRLGNEADTYVELNVEHKQTLDNGATTRFK
                     AMLADGQRDYNDWTGGSSNLNIRQAFAELGALPSFTGAFKDSTVWAGKRFDRDNFDIH
                     WLDSDVVFLAGTGGGIYDVKWNETFRSNFSLYGRNFGDLDDIDNNVQNYILTMNHYAG
                     PFQLMVSGLRAKDNDDRKDANGDLIQTDAANTGVHALVGLHNDTFYGLREGTAKTALL
                     YGHGLGAEVKGIGSDGALLSEANTWRFASYGTTPLGSGWYVAPAILAQSSKDRYVKGD
                     SYEWVTFNTRLIKEVTQNFALAFEGSYQYMDLKPKGYQNHNAVNGSFYKLTFAPTLKA
                     NDINNFFSRPELRLFATWMDWSSKLDDFASNDAFGSSGFNTGGEWNFGVQMETWF"
     gene            6713..8083
                     /locus_tag="LSX49_004421"
     CDS             6713..8083
                     /locus_tag="LSX49_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sucrose transporter subunit IIBC"
                     /protein_id="HBL7170735.1"
                     /translation="MDFDKIAQSLLPLLGGKENIASAAHCATRLRLVLVDDTLADQHA
                     IGQIDGVKGCFRNSGQMQIIFGTGVVNKVYAAFIQVAGISESSKADTARLAAQKLNPF
                     QRIARLLSNIFVPIIPAIVASGLLMGLLGMVKTYGWVNADNAIYILLDMCSSAAFIIL
                     PILIGFTAAREFGGNPYLGATLGGILTHPALTNAWGVAAGFQTMNFFGFEIAMIGYQG
                     TVFPVLLAVWFMSIVEKQLRRFIPDALDLILTPFLTVVISGFIALLIIGPAGRALGDG
                     ISFVLSTLIAHAGWLAGLLFGGLYSAIVITGIHHSFHAIEAGLLGNPAIGVNFLLPIW
                     AMANVAQGGACLAVWFKTKDTKIKAITLPSAFSAMLGITEAAIFGINLRFVKPFIAAL
                     IGGAAGGAWVVSVHVYMTAVGLTAIPGMAIVQPTSLVNYIIGMVIAFAVAFSLSLLLK
                     YKTDEE"
     gene            8083..9492
                     /locus_tag="LSX49_004422"
     CDS             8083..9492
                     /locus_tag="LSX49_004422"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001466359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBL7170736.1"
                     /translation="MSMPSQMPAILQAVMKGQSKALADAHYPCWHLAPVTGLMNDPNG
                     FCWSGGRYHLFYQWNPLACDHKYKCWGHWSSTDLLHWQHEPLALMPDKEYDRNGCYSG
                     SAVNNQGVLTLCYTGNVKFDDGSRTAWQCLATENNQGGFDKLGPVIPLPDGYTGHVRD
                     PKVWKHNSQWYMVLGAQDKEKRGKVLLYSSVDLYTWSFHGEIAGNGLNEIDNAGYMWE
                     CPDLFALDGEYILLCCPQGMAREHERYLNTYPCAWLHGQFDYETGKFTHGAFSELDAG
                     FEFYAPQTMEAPDGRRLLVGWMGVPDGEEMLQPTRKHHWQHQMTCFRELSFQKGKLFQ
                     MPIRELAQLREAEHFWQGKADHAPHVEIERLEMDIIPSGELYLNFGNALALHLNDDGI
                     QLQRRSLAGQEKLTRYWRGSVTSLKILCDSSSVEIFINNGEGVMSNRYFPHHPASLIL
                     QGESDVTLRYWSLRACMVE"
     gene            9518..10525
                     /locus_tag="LSX49_004423"
     CDS             9518..10525
                     /locus_tag="LSX49_004423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL7170737.1"
                     /translation="MRKTKRVTIKDIAELAGVSKATASLVLNGRGKELRVAQETRERV
                     LSIAQQQHYQPSIHARSLRDNRSHTIGLVVPEITNYGFAVFSHELETLCREAGVQLLI
                     SCTDENPSQETMVVNNMIARQVDGLIVASSMLHDNDYQKLSEQLPVVLFDRHMNGSTL
                     PLVITDSVSPTAALVADIARSHPDEFYFLGGQPRLSPTRDRLEGFTQGLQQAGVTLQP
                     EWIIHGNYHPSSGYEMFAALCARLGRPPKALFTAACGLLEGVLRYMSQYNLLDSKIHL
                     ASFDDHYLYDSLSVRIDTIQQDNRQLAFHCFELISQLIEGETPSPLQRYLPASLQKRY
                     R"
     gene            complement(10610..11281)
                     /gene="queE"
                     /locus_tag="LSX49_004424"
     CDS             complement(10610..11281)
                     /gene="queE"
                     /locus_tag="LSX49_004424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HBL7170738.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKEDATRLCIDTCIARNWRLSMQTHK
                     YLNIA"
BASE COUNT         2978 a         2624 c         2772 g         3096 t
ORIGIN      
        1 gcactaaata accgccatca accactaata aatgtccgtt gacataattc gatgccggac
       61 ttgcgaggaa tacggctgcc cccattaaat cctgagtatc accccaacgg tttgccggaa
      121 tatgatcaag aacacgctgg ttagtttctg gattactacg ggtcgccagc gtaatatcgg
      181 ttgcataata accaggagca ataccattca cctgaatatt atattggcct aattcatcgc
      241 aataggcttt ggtgaatccg gcaagagcat gtttagtggc agaataagca ggtgaccatt
      301 gaccacctaa gtaagagaac aatgaacaga tattaatgat tttaccgctt ttctgcggga
      361 tcataatttt tgccgcttcg tagcttaact cgaatgcggc ggtcaggttc acgtcaatca
      421 tcgggtccca gtcggcacga ccaaagtcca gcaccttatt cagcttacaa ataccggcat
      481 tattgaccag aatatcgacg gtaccgaagc gctcacagca ggcagcgata atcttctgcg
      541 gcgcgccttc tgcggtgata tccacctgca taaaatcaac ttcaacgccc tgtttttcaa
      601 tcatttcctt tgtttcgccg ttatctttga cgaaactagg aataaagaca tttgcgccag
      661 ctttggccaa cgccatggca aatgcctggc ctaaaccgct attcccgccg gtaacaattg
      721 ctgttttacc tttcagggag aaaaaatcca ttgagaacgc attgagagat tcgattgaca
      781 tagttagctc caatttccgt aaggcaaaaa aaaagaaagg taacttcccc cgcgagaggg
      841 aagttacctt tctcattatc tctggtaact ggagataatt tttagcataa ggacataact
      901 gctaatgtga tcgtaatcac agtgtgatgt tcgtattgtc aaataattta aaaaagcaga
      961 agcgtgatta ctctcacaca acacctctgc tttccatgtt atttcttatt gcaattacta
     1021 gagacctgag aaaagtaatc cacctgaaag ggcggcttac ttttctcttt tttttgtcta
     1081 ttacaaatgg gaatacgata tgcaacacaa ctcatatcgc cgttggataa ccctcgcgat
     1141 aattagtttt agcggcggcg ttagtttcga cctggcttat ttacgttata tttatcaaat
     1201 tcccatggca aaatttatgg gattcagcaa taccgagata ggtttaataa tgagtacctt
     1261 tggtattgcg gccattattt tctatgcccc tagcggcgtt attgccgata aattttcaca
     1321 tcgcaaaatg attacttccg cgatgatcat taccggatta ctgggtctgt taatggcaac
     1381 atatccaccg ctgtgggtaa tgctctgtat tcaggtcgcc tttgcgataa cgacgatttt
     1441 aatgctgtgg tcggtgtcga ttaaagccgc atcgttgctg ggcgatcata gcgagcaagg
     1501 gaaaattatg ggctggatgg aagggctgcg cggcgtcggt gtaatgtcgc tggcggtgtt
     1561 taccatgtgg gtcttttctc gctttgcacc ggatgacagc gccagcctga aaacggtcat
     1621 tattatctat agtgtggttt acattctgct gggcattttg tgttggtttt ttgttagcga
     1681 taacaacaac ctacgcagtg ccaataacga agaaaaacag tcattccagc ttagcgacat
     1741 cctggccgtt ttgcgcatca gcactacctg gtattgcagc atggtgattt ttggtgtctt
     1801 caccatctac gccattctga gttactccac caactatctg accgaaatgt acggcatgtc
     1861 gctggtggcg gcgagctaca tggggattgt gatcaacaaa atcttccgcg cgctgtgcgg
     1921 cccacttggc ggcattatca ccacctacag taaagtgaaa tcccctaccc gcgtggtcca
     1981 aatcctttcc atcatcggtt tgctggcgtt gacagccctg ctcgtcacga actctaaccc
     2041 gcaatcggtc gcgatgggga ttggcttgat tttattactg ggattcacct gttacgcctc
     2101 acgcgggctg tactgggcct gccctggcga agcgagaaca ccgtcttaca ttatgggcac
     2161 cacggtaggt atttgttcgg tgattggatt cctgccggat gtcttcgttt acccgattat
     2221 cggctactgg caagacaccc tgcccgctgc agaagcctat cgcaacatgt ggctaatggg
     2281 catggcggcg cttggcatgg tgatcatctt tacctttttg ctgttccaaa aaattcgtac
     2341 tgctgatagc gcccccgcaa tggctagcag caagtaagcc aggaaaatta caggagaaaa
     2401 atcatgtcga aaaaatacat catagggatt gatggcggaa gtcagagcac aaaagtggtg
     2461 atgtacgatc tggaaggtaa tgtggtttgc gaaggcaaag gcttattgca gccgatgcac
     2521 acgccagatg ccgataccgc agaacatcct gacgatgatt tatgggcatc actatgtttt
     2581 gccagtcacg atttgatgag ccagtttgcc gggaataaag aagatattgt cggcattggc
     2641 ctgggctcaa tccgttgctg ccgtgcgcta ttgaaagccg atggtacgcc agccgcgccg
     2701 ttgattagct ggcaggatgc acgcgttaca cgcccttacg aacacactaa tcctgacgtg
     2761 gcctatgtca cctctttttc gggttatctg acacatcgct taaccggcga gtttaaagac
     2821 aatatcgcca actattttgg tcagtggccg gtggattata agagctgggc atggagcgaa
     2881 gatgctacgg taatggaaaa gtttaatatc ccccgccaga tgctttttga cgtgcaaatg
     2941 ccgggcacca ttcttgggca tatcacacca caagctgcgc tggcgacaca tttcccggct
     3001 gggctgccgg ttgtttgtac caccagtgat aaaccggtag aagctctggg agccgggtta
     3061 ctggatgatg aaacggcggt aatttctctt ggcacctata tcgcgttgat gatgaacggc
     3121 aaagcactgc cgaaagatcc ggtggcgtac tggccgatta tgtcttctat tccgcaaaca
     3181 ttgctgtatg aaggttacgg tattcgcaaa ggcatgtgga cggtgagctg gctgcgcgac
     3241 atgttaggcg agtcgttaat tcaggatgcc aaagcacagg atctttcacc ggaagatttg
     3301 ctcaacaaaa aagcgtcttg cgtgccgcct ggctgtaatg gtctgatgac ggtgctggac
     3361 tggctgacca atccgtggga accgtacaaa cgcgggatta tgatcggttt tgattccagc
     3421 atggattacg catggatata tcgttcgata ctggaaagcg tggcgctgac gctgaagaat
     3481 aattacgaca atatgtgtca tgaaatgaat cactttgcaa agcatgtgat cattactggc
     3541 ggcggttcga acagcgatct gtttatgcag atttttgccg acgtgttcaa ccttccggca
     3601 cgccgaaacg ccattaacgg ttgtgcaagt ctgggggctg cgatcaatac ggcggtaggt
     3661 ctggggctat acccggatta cacaacggct gtcgataaaa tggttcgcgt gaaagatatc
     3721 ttcataccga ttgagagcaa tgccaaacgc tacgacgcga tgaataaagg cattttcaaa
     3781 gacctaacca aacatactga tgtgatcctg aaaaaatcgt atgaagtgat gcatggggaa
     3841 ttggggaatg cggattcgat ccagagctgg tcgaatgcgt aagtgagata aacagtgccg
     3901 ggtagatgat taatcccggc atattcacgt ttccactaca aaataccggg taaccactgc
     3961 tgaatattgt tctctcctga gcagcgttta tgctttaatt gctaaaccga tttaattagt
     4021 ttagcaatta gtatattgga gcctttatga gcacaagagt atgggtactc ggtgatgcgg
     4081 ttgttgattt attacccgaa agccagggga gactactaca gtgtcctggt ggggcgcctg
     4141 ctaatgttgc agtcggtatc gcaaggctgg gggggaaaag tgcctttatt ggcaaagttg
     4201 gcgatgatcc tttcggtcgc tttatgtatc aaacactgag tacagaaaat gttgatacac
     4261 gttatatgtc tcttgatcct caacatcgca cctcaattgt ggctgtagga cttgatgagc
     4321 aaggagaaag aaactttacc tttatggtac gcccaagtgc cgatcttttt ttacaacctg
     4381 atgaccttcc tgcatttggg ccgggtgaat ggctccatct ttgttccatt gcgctcagtg
     4441 cagaaccttc ccgaagtacc gcatttctgg ctatggagaa aatacgtcag gctggcggaa
     4501 acatcagttt tgatcccaat atccgcagcg atctctggca gagtgaagcg ctgttaagga
     4561 aataccttga tcgtgcgctt tcgctggcga atatcgctaa attgtccgaa gaagagttgt
     4621 tattcatcag tgacgaaagc caggttcagc aaggcgcata ttcattagta caacgttatc
     4681 cgttgacttt attgcttatt acacaaggaa aaaatggcgt acttgtgtat tttcaggggc
     4741 agtttatcca ctatcccgcc aaacctgttt ctgtcgtcga tacgaccggg gcaggagatg
     4801 cttttgtcgc tggattactt gccggtctgg ctgattctgg aataccaaca aataccagac
     4861 agcttgaacg aatcattgca caagctcaga tttgtggtgc tctggcgacc acggctaaag
     4921 gcgcgatgac cgccttaccc cgacaacacg atctcccttc acaatagtga tcctgctgtt
     4981 gtatctgtaa cccgatttgt cgtgcctgtc acatttacta aatcggttta gcgaaaataa
     5041 ttgctctggc taaaaagtca gctttattat caacacctaa accggtttag cattttagca
     5101 atttttataa ttctctgatg ggacgcgaca aattatgtat aaaaaaacaa ctttggcagt
     5161 gttaattgct ttgctgaccg gtgctacaac ggtacatgcg caaacggata ttagcagtat
     5221 cgaatctcga ctggcggcgt tggaacaacg tttaaaaaat gcggaatccc gcgcccaggc
     5281 ggcagaagca agggccaaaa cagctgaatt acaggttcag aaactggctg aaacacaaca
     5341 acaaaatcag ctaacaactc aagaagtagc acagagaaca gttcagctcg aacagaaatc
     5401 cgcagaaaac agtggttttg agtttcatgg ctatgcccgt tccgggttac tgatgaatga
     5461 tgccgcttcc agtagcaaaa gtgggccgta tctgactccc gcaggtgaaa ctggtggagc
     5521 tgttggccgt ctgggaaatg aagccgatac ctatgtcgag ttaaatgtag aacataaaca
     5581 aacactggat aacggtgcga ccacacgctt taaagcaatg ttggctgacg gacaaagaga
     5641 ttacaacgac tggactggcg gctccagtaa cctgaatatc cgacaggctt ttgccgaact
     5701 gggcgcatta ccaagtttta ccggagcatt caaagacagt actgtctggg ctggtaaacg
     5761 ctttgatcgc gacaattttg atattcactg gttagactcc gatgtcgtat ttttagcggg
     5821 aacgggcggc ggtatctatg acgtaaaatg gaacgagaca ttccgcagta acttttctct
     5881 ctacggacgt aatttcggcg atcttgatga tatcgacaat aacgttcaga actacatcct
     5941 caccatgaat cattatgcag gccccttcca gttgatggtt agcggattac gggcaaaaga
     6001 taatgatgat cgaaaagatg ccaatggtga tctcattcaa actgatgctg caaatactgg
     6061 cgtacatgcg ttagttggtc tgcacaatga cactttctat ggcctgcgtg aagggacggc
     6121 aaaaacagca ctgctatatg gccatggcct gggtgcggaa gtcaaaggga ttggctccga
     6181 tggcgctctg ctgtctgagg cgaatacctg gcgcttcgca tcttacggca caacacctct
     6241 gggaagcggt tggtatgttg cgccagcaat tctcgcacaa agcagtaaag atcgttacgt
     6301 caaaggcgat agctacgaat gggtgacctt caatacacgt ctgatcaaag aggtaacaca
     6361 gaattttgct ctggcctttg agggtagcta tcaatatatg gatctgaagc caaaggggta
     6421 tcaaaaccac aacgccgtaa acggcagctt ctataaactc acctttgctc caactctaaa
     6481 agctaacgat atcaataatt tctttagccg tccggagctt cgcctgtttg ccacctggat
     6541 ggactggagc agcaaacttg atgattttgc cagcaatgat gctttcggca gcagtggttt
     6601 caatactggc ggagagtgga attttggtgt ccaaatggaa acctggtttt aataccagac
     6661 agcctcacgg atgtgaggct tttactgaaa taacaatgaa ttagagggtt atatggattt
     6721 cgataaaatc gcccaatcgt tgcttccttt attaggtggt aaggagaaca tcgccagtgc
     6781 agcacattgc gccactcgcc tacggctggt actggttgac gacacacttg ccgatcaaca
     6841 tgccattggc cagattgatg gagtgaaagg ttgttttcgt aattcagggc aaatgcaaat
     6901 catctttggc accggcgtgg ttaataaagt ctatgctgcc tttattcagg ttgcaggtat
     6961 tagcgaatcc agtaaagcag ataccgctcg actcgccgct caaaaactca atccttttca
     7021 gcgaatagca cggctacttt ctaatatttt tgtccccatc attccagcca ttgttgcttc
     7081 tggtttatta atggggcttc tgggaatggt gaaaacatat ggctgggtga atgccgataa
     7141 tgcgatttat atcctgctgg atatgtgcag ttcagccgca tttattattc tccccatcct
     7201 tattggcttt actgctgctc gtgaatttgg tggaaatcct tatcttggcg cgacattagg
     7261 agggattctg actcacccgg cactcacaaa tgcctggggc gttgctgcgg gatttcagac
     7321 aatgaacttc ttcggttttg aaatcgccat gattggctat cagggaacgg ttttccccgt
     7381 gcttctggca gtatggttta tgagcatagt ggaaaaacag ttacgcaggt ttatccctga
     7441 tgctctggat ctcattctga cgccatttct gactgtcgtc atttctggct ttatcgctct
     7501 tttgattatt ggtccggcag gacgagcgtt aggtgacggt atctctttcg ttctcagcac
     7561 gctgattgca cacgcaggct ggttagcagg gttgttattc ggcgggctat attcagcgat
     7621 tgttattacg ggtattcatc atagcttcca cgcaattgaa gcaggacttt taggtaaccc
     7681 tgcaatcggt gttaatttcc tgctgcctat ttgggcaatg gcaaacgttg cgcaaggcgg
     7741 tgcatgtctg gcggtatggt ttaaaaccaa agatacaaaa attaaagcaa tcaccctacc
     7801 ctcggccttt tccgcaatgt tagggattac tgaagccgct atttttggta tcaaccttcg
     7861 ttttgttaaa ccttttattg cggccttaat tggtggcgct gccggcggtg cctgggttgt
     7921 ctctgttcac gtttatatga ctgccgttgg tctgaccgca atacccggca tggcaatcgt
     7981 tcagccaaca tcgttggtta attatattat tggaatggtg attgctttcg ctgtcgcttt
     8041 tagcctctct ttattactca aatacaaaac ggacgaggag taatgtcgat gccttcacaa
     8101 atgcccgcga ttttacaggc agtgatgaaa ggtcagtcca aagcactggc agatgcccac
     8161 tatccttgtt ggcatctcgc tccagtcacc ggactaatga acgatccaaa tggcttttgt
     8221 tggtctggag gccgctatca tctgttttat caatggaatc cactggcttg tgatcataag
     8281 tacaaatgtt gggggcactg gagttcgacg gatttattgc actggcagca tgaaccatta
     8341 gcgctaatgc ccgataaaga gtacgaccgt aatggttgtt actcaggaag cgcggttaat
     8401 aatcagggcg ttctcacact ttgctatacc ggtaatgtta agtttgatga tggcagcaga
     8461 acagcatggc aatgtctggc caccgaaaat aaccagggcg ggtttgataa actaggccct
     8521 gtcataccgt tacctgatgg ttacaccgga catgttcgtg atccaaaagt ctggaagcac
     8581 aacagccaat ggtacatggt gcttggcgcg caagataaag agaaacgggg gaaagtactg
     8641 ctgtattcct ctgtcgatct ctatacctgg tcttttcatg gagaaattgc tggtaatggt
     8701 ctgaatgaaa tagataacgc aggatacatg tgggaatgtc ctgatctttt cgcccttgat
     8761 ggtgaataca ttctcctctg ctgcccccag ggaatggcgc gcgaacatga gcgctatctg
     8821 aatacttatc cctgcgcctg gctacatgga cagtttgatt acgagacagg caagtttacg
     8881 catggcgctt tctcagagct ggatgcggga tttgaattct atgcaccaca gacgatggaa
     8941 gccccggacg ggcgacgatt gctggtcggc tggatggggg ttcctgatgg cgaagagatg
     9001 ttgcaaccaa ccagaaagca tcattggcag catcaaatga cctgttttcg cgaactctca
     9061 ttccagaagg gaaaattgtt tcagatgcca atcagggaac tcgcgcaact gcgtgaagct
     9121 gaacacttct ggcaaggaaa agcggatcat gcgccgcatg tcgaaattga acgcctggaa
     9181 atggacatca ttccgtcggg tgagctgtat ctgaattttg gcaatgcgct ggcactgcat
     9241 cttaatgacg atggtattca actacagagg agaagccttg cagggcaaga gaaactaact
     9301 cgttactggc gaggaagcgt aacgtcactg aagattctct gtgacagttc cagcgtagag
     9361 atattcatca ataatggtga aggtgtaatg agtaatcgtt attttcccca tcatccagct
     9421 tcgctgatat tacagggtga gtctgacgtc acgttacgct actggtcgct acgcgcctgc
     9481 atggtagaat gagggttttg aattacggat cctcgtcgtg agaaaaacca aacgcgttac
     9541 tattaaagac attgctgaac tggcgggagt gtcgaaagca accgccagtc tggttctcaa
     9601 tggtcgtggc aaagagttac gtgttgcgca ggaaacgcgt gagcgtgtgc tgagtattgc
     9661 ccaacagcag cattatcagc ccagcattca tgcccgctca ttacgggaca accgcagtca
     9721 taccattggt ctcgtcgttc ctgaaatcac taactacgga tttgcagtat tttcccatga
     9781 actggaaaca ttgtgtcggg aagcgggcgt ccaactcctc atatcctgta ctgatgaaaa
     9841 tccttcacag gaaacaatgg tggtgaacaa tatgattgcc cgccaggttg atgggttaat
     9901 cgtcgcatcc agtatgctgc atgataatga ctatcaaaaa cttagcgagc aattacctgt
     9961 tgtgttgttc gatcgccaca tgaacggcag cacattgcca ttggtcatta ctgactctgt
    10021 ttctcccacc gccgctctgg tggcagatat tgcacggagt cacccggatg aattctattt
    10081 tctgggggga caaccccgtt tgtcaccgac tcgtgatcga ctggaaggat ttacacaagg
    10141 cttgcagcaa gccggagtaa cgctacaacc tgaatggatt attcacggta attatcatcc
    10201 gagctcaggc tatgaaatgt ttgccgcgct atgcgctcgt ttaggacgtc cccctaaagc
    10261 cttattcact gccgcttgtg gattactgga aggcgttctg cgctatatga gccaatataa
    10321 tttactcgac agtaaaatcc acctggcgag ttttgatgat cattacttgt atgattcact
    10381 ttcggtaaga atcgacacaa tacaacagga taatcgccaa cttgcttttc actgctttga
    10441 acttatttcg caactgattg aaggtgaaac gccatcccca ttacagcgtt atcttcctgc
    10501 cagtctacaa aaacgctacc gataatcccg tcactatctt gcatcgcccc tgtaaaacgg
    10561 ggcgattatt ttcatcctga acgttaaata tcaatgatgc ataatcaaat caggcaatat
    10621 ttaaatattt atgcgtttgc atcgacaaac gccagttgcg cgcaatgcag gtatcgatac
    10681 ataaacgcgt agcatcttcc ttctggctaa ttggctgcag tgcaatgact cgcggtttat
    10741 catcggtcag cgtcgcaagc aattcatcca gtgcttcgat atcacgtacg cgtcccactg
    10801 ggtgtttgat ttcgttggct cgctccagtg cctgtgacaa cacttcatag ccaccgcgca
    10861 tattcagctt tggcgacacg gtgacccagg tattcggtgt acagcgtact tcatgagtac
    10921 cactggtttc tatctggcag ctaaaaccgt tcttttcgag caggtcagtc agcggcagca
    10981 aatcatgaat gcaaggctca ccacccgtaa tcaccacgtg acgcgcggtg tatccctgac
    11041 ggccaatgac agccagcaaa tcttcactgc tcgccgcccc ccacttatca ctctctttgg
    11101 tcttcgccag aatgctgaaa agggagactt cccgatcctc aagcttttcc caggtgtgtt
    11161 tggtgtcgca ccaggcacag ccaaccggac atccctgtaa acgaataaaa atggcgggga
    11221 cgccggtaaa gtaaccctca ccttgcaggg tctggaacat ctcgttaatc gggtactgca
    11281 tagcattctc tgtgaagtgg ataattgtta attattgcag atcctgccac aacaatcatg
    11341 tcttattaac attctgttac cggcaggttt aaagaaaaat gcgaaacata tcgttaataa
    11401 taaaagggag tgacgtatta tgtcagaaag aaataaagta aagggattta atcatgtcaa
    11461 aaacattcac
//
LOCUS       DAFGPF010000141        11447 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFGPF010000141 DAFGPF010000000
VERSION     DAFGPF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11447
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.141"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            225..584
                     /locus_tag="LSX49_004425"
     CDS             225..584
                     /locus_tag="LSX49_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1889 family protein"
                     /protein_id="HBL7170739.1"
                     /translation="MQIKVIYSLIDNMVNFKDKNMPAVIDKALDFIGAMDVSAPTPSS
                     MNESTAKGIFKYLKELGVPASAADITARADQEGWNPGFTEKMVGWAKKMESGERSVIK
                     NPEYFSTYMQEELKALV"
     gene            complement(704..883)
                     /locus_tag="LSX49_004426"
     CDS             complement(704..883)
                     /locus_tag="LSX49_004426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HBL7170740.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            957..2318
                     /gene="pabB"
                     /locus_tag="LSX49_004427"
     CDS             957..2318
                     /gene="pabB"
                     /locus_tag="LSX49_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HBL7170741.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSHLSHLPWAMLLHSGYADHPYS
                     RFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPAHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALVVDHQRQTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQAAILSLSPERFILCDNGEIQTRPIKGT
                     LPRLPDLLEDSKQAEKLANSTKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTTINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQ
                     LEK"
     gene            2322..2900
                     /locus_tag="LSX49_004428"
     CDS             2322..2900
                     /locus_tag="LSX49_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBL7170742.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEGEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            3084..4448
                     /gene="sdaA"
                     /locus_tag="LSX49_004429"
     CDS             3084..4448
                     /gene="sdaA"
                     /locus_tag="LSX49_004429"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBL7170743.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPFKSATELLAYCNETGFSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            4579..6177
                     /locus_tag="LSX49_004430"
     CDS             4579..6177
                     /locus_tag="LSX49_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBL7170744.1"
                     /translation="MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQ
                     RVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCSVAHLPLRKQAAKLQTVRSIGLV
                     QDGTLYCSSIFGYRNVPVVDILAELPAPQPLLRLTTDRALIKGSPVLIQWTPAAGSSN
                     AGVMEMINIDLLTAMLLEPQLPQISSASLTVDSRHLLYGNGLVDSLPQPENNENYQVS
                     SQRFPFTINVNGPGATALAWHYLPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLG
                     LAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFIPIAEEHHLIVPLTR
                     YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITE
                     RDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSD
                     AVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRSHGVHILQGYLYAQPMPLRDFP
                     KWLAGSQPPPARHNGHITPVMPLR"
     gene            complement(6181..7737)
                     /gene="yoaE"
                     /locus_tag="LSX49_004431"
     CDS             complement(6181..7737)
                     /gene="yoaE"
                     /locus_tag="LSX49_004431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HBL7170745.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            8201..9172
                     /gene="manX"
                     /locus_tag="LSX49_004432"
     CDS             8201..9172
                     /gene="manX"
                     /locus_tag="LSX49_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBL7170746.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPIEKAAPAPAAAAPKVAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            9235..10035
                     /gene="manY"
                     /locus_tag="LSX49_004433"
     CDS             9235..10035
                     /gene="manY"
                     /locus_tag="LSX49_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBL7170747.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            10048..10899
                     /gene="manZ"
                     /locus_tag="LSX49_004434"
     CDS             10048..10899
                     /gene="manZ"
                     /locus_tag="LSX49_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HBL7170748.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            10954..11412
                     /locus_tag="LSX49_004435"
     CDS             10954..11412
                     /locus_tag="LSX49_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HBL7170749.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ"
BASE COUNT         2813 a         2887 c         2861 g         2886 t
ORIGIN      
        1 ctataaaact aactatataa ataaacataa tcatgccgtt atgttcgccc ttcgattagc
       61 atctctggtt ttctttctta cctgaacaat ctggttatag cgtgaggact gaccattaat
      121 tttctccatc ttactggata acacaccatg agctgctacc tttaaaacac ctgaatgtca
      181 ataggttaac tcgtgccata tcgttataat ccctttgata ttagatacaa attaaggtca
      241 tatatagcct tatcgataac atggttaatt ttaaggataa gaatatgcct gctgtaatag
      301 ataaagccct ggatttcatt ggtgccatgg atgtatcagc gccaacacca agttcgatga
      361 atgaaagtac ggcgaaggga atctttaaat atttaaaaga actgggagta cccgcgagtg
      421 ccgctgatat tacggcgcga gctgaccagg aaggctggaa ccctggtttc acggaaaaaa
      481 tggttggatg ggcaaaaaaa atggagtctg gtgaacgctc tgtgattaaa aatcctgaat
      541 acttttcaac atatatgcag gaagaactaa aagcactggt ttgagttaaa ttcacatcag
      601 cataaatggg tcaggacgct tttaatcaca tataaaaagc gtcctttttc tcacaatcaa
      661 ataatcatcg gcttctataa cgaaagcgat acggattagt gtgttactcg tcttcatcct
      721 caaaacgcgc cacgattcgc tcgccggaat ggttggcacg cagctcttct gccaccagcg
      781 cgattgcctg gccgctgctc atcccttgtg ccatcagttc ctggatccgc tcgacggctt
      841 tttgctgctg ttcatgggtg agtgaaggta aacctgcaaa cattgttaac tcctgctaaa
      901 ttgttggcgc taattatttc atgctacccg gcacatagcc agtagagtca ggactgatga
      961 agacgttatc tcccgctgtg attactttac cctggcgtca ggacgccgct gaattttatt
     1021 tctcccactt aagccacctg ccgtgggcga tgcttttaca ctccggctat gccgatcatc
     1081 cgtatagccg ctttgatatt gtggtcgccg agccaatttg cactttaacc actttcggta
     1141 aagaaaccgt tgttagtgaa agcgaaaaac gcacaacgac cactgatgac ccgctacagg
     1201 tgctccagca ggtgctggat cgtgcagaca ttcgcccagc gcataacgaa gatttgccat
     1261 ttcagggcgg cgcgctgggg ttgtttggct acgatctggg ccgccgtttt gagtcactgc
     1321 cagaaattgc ggaacaagat atcgttctgc cggatatggc agtgggtatc tacgactggg
     1381 cgctggttgt cgaccaccag cgtcaaacag tttctttgct gagtcataat gatgtcaatg
     1441 cccgtcgggc ctggctggaa agccagcaat tctccccgca ggaagatttc acactcactt
     1501 ccgactggca atccaatatg acccgcgaac agtacggcga aaaatttcgc caggtacagg
     1561 aatatctgca cagcggtgat tgctatcagg tgaatctcgc ccagcgtttt catgcgacct
     1621 attctggcga tgaatggcag gcattccttc agcttaatca ggccaaccgc gcgccgttta
     1681 gcgctttttt acgtcttgaa caggctgcta ttttaagcct ttcaccagag cggtttattc
     1741 tttgtgataa tggtgaaatc cagacccgcc cgattaaagg cacgctacca cgcctgcccg
     1801 atcttctgga agatagcaaa caagcagaaa aactggcgaa ctcaacgaaa gatcgtgccg
     1861 aaaatctgat gattgtcgat ttaatgcgta atgatatcgg tcgtgttgcc gtagcaggtt
     1921 cggtaaaagt accagagctg ttcgtggtgg aacccttccc tgccgtgcat catctggtca
     1981 gcaccataac ggcgcaacta ccagaacagt tacacgccag cgatctgctg cgcgcggctt
     2041 ttcctggtgg ctcaataacc ggggctccga aagtacgggc tatggaaatt atcgacgaac
     2101 tggaaccgca gcgacgcaat gcctggtgcg gcagcattgg ctatttgagc ttttgcggca
     2161 acatggacac cagcattact atccgcacgc tgactaccat taacggacaa atttactgct
     2221 ctgcgggcgg tggaattgtt gccgatagcc aggaagaagc ggaatatcag gaaacttttg
     2281 ataaagttaa taagatatta cgccaactgg agaagtaaga cgtggaatac cgtagcctga
     2341 cgcttgatga ttttttatcg cgctttcaac ttttgcgccc gcaaattaac cgggaaacct
     2401 taaatcatcg tcaggctgcc gtgttaatcc ccatcgtccg ccgaccgcaa ccggggttgt
     2461 tgctgactca gcgttcgatt catctgcgta aacacgctgg acaagtggca ttccctggag
     2521 gcgcagtcga tgacacggac gcatcagtta tcgccgctgc gctgcgcgaa gctgaagaag
     2581 aggtcgctat accgccttcc gccgttgagg ttatcggcgt gctgccgccc gtcgatagcg
     2641 tcactggcta ccaggtaacc ccagtggtcg gcattatccc gcccgatctg ccgtatcgcg
     2701 ccagtgaagg tgaagtctcc gccgtctttg aaatgccgct cgcccaggca ttacatctgg
     2761 gtcgttatca tcctttagat atctaccgcc gtggcgattc acatcgggta tggctgtcct
     2821 ggtacgaaca gtattttgta tggggaatga ccgcaggcat aattcgtgag ctggcgctgc
     2881 aaattggtgt gaaaccctga ctatacttat ctttacatct acaaaacact acttgagaca
     2941 atcatcgcaa tattagttaa atcgcggttt ttgattagtt taattcatgt gaatagttaa
     3001 gccagtcgcc gcgttccctc ttacactatg cgctgttatt agttcgttac tggaagtcca
     3061 gtcaccttgt caggagtatt atcgtgatta gtctattcga catgtttaag gtggggattg
     3121 gtccctcatc ttcccatacc gtagggccta tgaaggcggg taaacagttc gtcgatgatc
     3181 tggtcgaaaa aggcttactg gatagcgtta ctcgcgttgc cgtggacgtt tatggttcac
     3241 tgtcgctgac gggtaaaggc caccacaccg atatcgccat tattatgggt cttgcaggta
     3301 acgaacctgc caccgtggat atcgacagta ttcccggttt tattcgcgac gtagaagagc
     3361 gcgaacgtct gctgctggca cagggacggc atgaagtgga tttcccgcgc gacaacggga
     3421 tgcgttttca taacggtaac ctgccgctgc atgaaaacgg tatgcaaatc cacgcctata
     3481 acggcgatga agtcgtctac agcaaaactt attattccat cggcggcggt tttatcgtcg
     3541 atgaagaaca ctttggtcag gatgctgcca acgaagtgag cgtgccgtat ccgttcaaat
     3601 ctgccaccga actgctcgcg tactgtaatg aaaccggctt ttcgctgtct ggtctcgcta
     3661 tgcaaaacga actggcgctg cacagcaaga aagagatcga cgagtatttc gcgcatgtct
     3721 ggcaaaccat gcaggcatgt atcgatcgcg ggatgaatac cgaaggcgta ctgccaggcc
     3781 cgttgcgcgt gccacgtcgt gcgtcggccc tgcgccggat gctggtttcc agcgataaac
     3841 tgtctaacga tccgatgaat gtcattgact gggtaaacat gtttgcgctg gcagttaacg
     3901 aagaaaacgc cgccggtggc cgtgtggtaa ctgcgccaac taacggtgcc tgcggtatcg
     3961 ttccggcagt gctggcttac tatgaccact ttattgaatc agttagccca gacatctata
     4021 cccgttactt tatggcagcg ggcgcgattg gtgcactgta taaaatgaac gcgtctattt
     4081 ccggtgcgga agtcggttgc cagggcgaag taggtgttgc ctgttcaatg gctgctgcgg
     4141 gccttgccga gctgttgggc ggtagcccgg aacaggtttg tgtggcagcg gaaattggca
     4201 tggaacacaa cctcggtctg acctgcgacc ccgttgcagg gcaagttcag gtgccgtgca
     4261 ttgaacgtaa tgccattgcc tctgtgaagg cgattaacgc cgcacggatg gctctgcgcc
     4321 gcaccagtgc accgcgcgtc tcgctggata aggtcatcga aacgatgtac gaaaccggta
     4381 aggacatgaa cgctaaatac cgcgaaacct cacgcggtgg tctggcaatc aaagtccagt
     4441 gtgactaata cttcttattc gcccatctgc aacggatggg cgaatttatt cccgctttct
     4501 cgtctgctgt aattttcccc actacacttc cactgttgcg tcaggcgttt gtcgccatac
     4561 gcttacaggg tggcccgcat gcaaaaagca caacggatca ttaaaaccta tcgccgtaat
     4621 cgaatgattg tttgtacgat ttgcgcactc gttacgctcg cttcgaccct gagcgtgcga
     4681 tttatttcac agcgtaactt aaatcaacaa cgggtagtac aattcgccaa tcacgctgta
     4741 gaggaattag ataaagtact gcttccccta caggcaggta gcgaagtctt gcttccgctg
     4801 attggtctgc cctgctctgt cgcccatttg ccattacgta aacaggcggc aaaactccaa
     4861 actgtgcgat ccattggcct ggtgcaagac ggcacacttt attgctccag catttttggt
     4921 tatcgcaatg tgcccgtcgt ggacattctg gctgaacttc ctgcaccgca accactttta
     4981 cgactgacga ccgaccgtgc cctgataaaa ggcagtccgg ttttgattca atggacgcct
     5041 gcagcgggca gtagcaatgc tggggtcatg gagatgatta acatcgactt actgacggca
     5101 atgctccttg aaccacaact gccgcaaatc agtagcgcca gcctgacggt ggacagtcgg
     5161 catttgctct atggtaatgg gctggtagat tcccttccgc aacctgaaaa caatgaaaac
     5221 tatcaggttt cttcgcaacg ctttcctttt accattaacg ttaatggccc gggggctacg
     5281 gcgctggcat ggcactatct tccaacacaa ttaccgctgg cggtgctgct aagtttactg
     5341 gtgggctaca tcgcctggct ggcgaccgct taccgaatga gcttttcccg cgagatcaat
     5401 ctgggcctgg cgcaacatga gttcgaattg ttctgtcagc ctttgcttaa tgcgcgcagc
     5461 cagcaatgta ttggtgtaga gattttgctg cgctggaaca atccgcgtca gggctggatt
     5521 tcaccggatg tgtttattcc tatcgcggaa gaacatcatt taattgtgcc actgacccgc
     5581 tatgtgatgg cagaaaccat tcgtcagcgc catgttttcc caatgagtag tcagtttcat
     5641 gttggcatta acgtcgcacc cagccatttt cgccgtggtg tgctgataaa agatctcaat
     5701 cagtactggt ttagcgctca cccgattcag caactgatcc tcgaaatcac cgaacgcgat
     5761 gccttactgg atgttgatta ccggattgcc cgcgagctgc atcgtaaaaa cgtcaaactg
     5821 gcgattgatg acttcggcac cggcaacagt tcattttcct ggcttgaaac attacgtcct
     5881 gacgtgctga aaattgataa gtcatttacc gcagctatag gttctgacgc ggttaactcg
     5941 acggtgaccg atatcatcat cgcactgggg caaagactga atattgaact ggtggcggag
     6001 ggcgtagaaa cgcaagaaca ggcgaagtat ttgcgcagtc atggcgtgca tattttgcaa
     6061 gggtatttgt acgcacagcc gatgccgcta cgtgattttc ccaaatggct ggcgggcagc
     6121 caaccgccgc ccgcccggca taatggacat atcacgcccg ttatgccgtt acgttaacgc
     6181 ttactcatct tcatcgtgcg ccggttgctc tttaacaatg cgaaccagat caacacgata
     6241 atcattggct tcaatgatgg tgatatgcag tggacctaca tcaatcacat cgcccacacg
     6301 gggaatgtga ccatttgccg agatcacgag gcccgcgacc gtcgcgatat catcgtcatc
     6361 ggcaaggtgc tcaacatcaa gcgcctgctg caaggcatgc aaatctgtac cgccttttac
     6421 cagccagccg tcaccgtcgg taatgatttc cggcgtttcg tcagcgtccg ggaattcacc
     6481 cgcaatggct tccagcacat ccagcggcgt gaccagacct tgtaccacac caaactcgtt
     6541 ggtcacgata acaaagctcc cgcgagcacg acgcagcacg cccagcaggt tgatcggatc
     6601 gagggtttcc gggacgataa tcgccggaga cgccgaagct atcgccgcca catcaactcc
     6661 ctcttccagc gccaccagca gttctttagc acgtacgatg ccgataattt catccagttc
     6721 accgcgacat accgggaaca aactgtgcgg tgaggagagc agttgctcgc ggatttcatc
     6781 gaccccgaga ttagcatcaa cccagcttat ttcaccgcgc ggcgtcatga tcccgcgcag
     6841 agaacgcgac gccagcgtca gtacgccgtt aatcatgtaa cgttcttctt cggcaaacgc
     6901 accttccggg atcggcatcg gcatcgggtt atcggcatcg tgctgaacat tggcctgacg
     6961 tttcccgccc atcaaacgca ggatggcatc ggcagtacgc gctcgcagcg gcaaagtcga
     7021 ctggtgacga ataaagttgc gacgcgcaat ctggttaaac acttcgatga tgatcgagaa
     7081 gccaatcgcg gcatacaggt aacctttcgg aatgtggaaa ccgaaacctt ctgccaccag
     7141 actcagacca atcattaaca ggaagctcag acagagcacc accaccgtgg ggtgctggtt
     7201 aacaaatcgc gtcagcggtt tcgatgccag cagcataacc gccatcgcaa tcactaccgc
     7261 cgccatcatc accggcaaat ggttaaccat ccctactgca gtaattaccg catccaacga
     7321 aaagacggcg tcaaggatga caatctgtgt gacgaccacc cagaaactgg cgtagccttt
     7381 accgtggccg gaatcatgat cgcggttttc cagccgttca tgcagttcgg ttgttgcttt
     7441 gaacagcaag aatatgcccc cgaacaacat aatcaggtcg cgtccggaga aggagaaatc
     7501 catgacggta aatagcggtt tggtcagcgt gaccatccat gaaatcagcg acagcagccc
     7561 cagacgcata atcagcgcca gtgataatcc cagcaaacgc gctttatcgc gttgttttgg
     7621 cggcagtttg tcagcaagaa tggcgatgaa gaccaggtta tcgataccca gcacaatttc
     7681 gagaacaaca agcgtgagta gccccgccca aatcgagggg tccattaaga attccatgac
     7741 aagctcctgc ttaaggaata gctattcgac gccagaaata atgcaggcgt aacgacaaaa
     7801 tgcaaacgaa aggtgcggca taaagtgcca gaaagacagg cgttaaaagg cctgatgctg
     7861 aaatgacgtc ggtgacgatc catactgcgg gctactgccc tatactccat ggttgttaaa
     7921 caggagttaa acatatcaga gacgcctctg atttggcaaa gatttacctt cctttgcaaa
     7981 cgaatgtgac aaggatattt tacctttcga aatttctgct aatcgaaagt taaattacgg
     8041 atcttcatca cataaaataa ttttttcgat atctaaaata aatcgcgaaa cgcagggggt
     8101 ttttggttgt agcccttatc tgaatcgatt cgattgtgga cgacgattca aaaatacatc
     8161 tggcacgttg aggtgttaac gataataaag gaggtagcaa gtgaccattg ctattgttat
     8221 aggcacacat ggttgggctg cagagcagtt gcttaaaacg gcagaaatgc tgttaggcga
     8281 gcaggaaaac gtcggctgga tcgatttcgt tccaggtgaa aatgccgaaa cgctgattga
     8341 aaagtacaac gctcagttgg caaaactcga caccactaaa ggcgtgctgt ttctcgttga
     8401 tacatgggga ggcagcccat tcaatgctgc cagccgcatt gtcgtcgaca aagagcatta
     8461 tgaagtcatt gcaggcgtta acattccaat gctcgtggaa acgttaatgg cccgagatga
     8521 tgaccctagc tttgatgaac tggtggcact ggcagtagaa acaggccgtg aaggcgtgaa
     8581 agcactgaaa gccaaaccga ttgaaaaagc cgcgccagca cccgctgccg cagcacccaa
     8641 agtggctcca actccggcaa aaccaatggg accgaacgac tacatggtta ttggccttgc
     8701 gcgtatcgac gaccgtctga ttcacggtca ggtcgccacc cgctggacca aagaaaccaa
     8761 tgtctcccgt attattgttg ttagtgatga agtggctgcg gataccgttc gtaagacact
     8821 gctcacccag gttgcacctc cgggcgtaac agcacacgta gttgatgttg ccaaaatgat
     8881 tcgcgtctac aacaacccga aatatgctgg cgaacgcgta atgctgttat ttaccaaccc
     8941 aacagatgta gagcgtctcg ttgaaggcgg cgtgaaaatc acctctgtta acgtcggtgg
     9001 tatggcattc cgtcagggta aaacccaggt gaataacgcg gtttcggttg atgaaaaaga
     9061 tatcgaggcg ttcaagaaac tgaatgcgcg cggtattgag ctggaagtcc gtaaggtttc
     9121 caccgatccg aaactgaaaa tgatggatct gatcagcaaa atcgataagt aacgtattgt
     9181 gttgattatc actcagtttt cacacttaag tcttacgtaa acaggagaag tacaatggag
     9241 attaccactc ttcaaattgt gctggtattt atcgtagcct gtatcgcagg tatgggatca
     9301 atcctcgatg aatttcagtt tcaccgtccg ctaatcgcgt gtaccctggt gggtatcgtt
     9361 cttggcgata tgaaaaccgg tattattatc ggtggtacgc tggaaatgat cgcgctgggc
     9421 tggatgaaca tcggtgctgc cgttgcgcct gacgccgctc tggcttccat catttctact
     9481 attctggtta tcgcaggtca tcagagcatt ggtgcaggta tcgcactggc aatccctctg
     9541 gccgctgcgg gccaggtact gaccatcatc gttcgtacta tcaccgttgc tttccagcac
     9601 gctgcggata aggctgctga taacggcaac ctgacagcga tttcctggat ccacgtttct
     9661 tctctgttcc tgcaagcaat gcgtgtggct attccggccg tcatcgttgc gctgtctgtt
     9721 ggtaccagcg aagtccagaa catgctgaat gcgattccgg aagtggtgac caatggtctg
     9781 aatatcgccg gtggcatgat cgtggtggtt ggttatgcga tggttatcaa catgatgcgt
     9841 gctggctacc tgatgccgtt cttctacctc ggcttcgtaa ccgcagcatt caccaacttt
     9901 aacctggttg ctctgggtgt gattggtact gttatggcag tgctctacat ccaacttagc
     9961 ccgaaataca accgcgtagc cggtgcgcct gctcaggctg ctggtaacaa cgatctcgat
    10021 aacgaactgg actaacaggt gagcgaaatg gttgatacaa ctcaaactac caccgagaaa
    10081 aaactcactc aaagtgatat tcgtggcgtc ttcctgcgtt ctaacctctt tcagggttca
    10141 tggaacttcg aacgtatgca ggcactgggt ttctgcttct ctatggtacc ggcaattcgt
    10201 cgcctctacc ctgagaacaa cgaagctcgt aaacaagcta ttcgccgtca cctggagttc
    10261 tttaacaccc agccattcgt ggctgcgccg attctcggcg taaccctggc actggaagaa
    10321 cagcgtgcta atggcgcaga gatcgatgac ggtgctatca acggtatcaa agtcggtttg
    10381 atggggccgc tggctggtgt aggcgacccg atcttctggg gaacggtacg tccggtattt
    10441 gcagcgctgg gggctggtat cgcgatgagc ggcagcctgt taggtccgct gctgttcttc
    10501 atcctgttta acctggtgcg tctggcaacc cgttactacg gcgtagcgta tggttactcc
    10561 aaaggtatcg atatcgttaa agatatgggt ggtggcttcc tgcaaaaact gacggaaggg
    10621 gcgtctatcc tcggcctgtt tgtcatgggg gcattggtta ataagtggac acatgtcaac
    10681 atcccgctgg tggtctctcg cattactgac cagacgggca aagaacacgt taccactgtc
    10741 cagactattc tggaccagtt aatgccaggc ctggtaccac tgctgctgac ctttgcttgt
    10801 atgtggctgt tgcgcaaaaa agttaacccg ctgtggatca tcgttggctt cttcgtcatc
    10861 ggtatcgctg gttacgcttg cggcctgctg ggactgtaag actgttgtac actaccgggg
    10921 ccttttggcc ccgttttttt atctggagga ttaatgacaa tcacggacct ggtactgatt
    10981 cttttcatcg ccgcacttct ggccttcgcg atctacgatc agttcatcat gccccgccgt
    11041 aacggcccca ccctgctggc aattcctttg ctccggcgtg gtcgcatcga tagcgttatc
    11101 ttcgtcggat tgattgtcat tcttatctat aacaacgtca cgaatcatgg cgcgcttata
    11161 acaacatggt tattaagtgc actggctctg atgggttttt atatattctg gattcgcgtt
    11221 ccgaagatca tctttaaaca aaaaggtttt ttcttcgcca atgtctggat tgaatatagc
    11281 cgaatcaaag cgatgaactt gtcggaagat ggcgtgttgg tgatgcaatt agaacagcgt
    11341 cggctgttaa tccgcgttcg aaatatcgac gatttggaaa aaatttataa gcttctcgtt
    11401 tcaactcaat aagttatgaa tttagccaaa gctatgttta gtgtatt
//
LOCUS       DAFGPF010000142        11299 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFGPF010000142 DAFGPF010000000
VERSION     DAFGPF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11299
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.142"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1..513
                     /locus_tag="LSX49_004436"
                     /pseudo
     CDS             1..513
                     /locus_tag="LSX49_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            complement(537..1142)
                     /locus_tag="LSX49_004437"
     CDS             complement(537..1142)
                     /locus_tag="LSX49_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL7170750.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGCAGYDVVGIFKETG
                     SGTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMN
                     GMAFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSD
                     RLLPKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
     gene            1237..4134
                     /locus_tag="LSX49_004438"
     CDS             1237..4134
                     /locus_tag="LSX49_004438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="HBL7170751.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRR
                     PENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQ
                     HMDTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVS
                     TIERLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGN
                     NSAAANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWA
                     ILAVCVVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALG
                     ASLLEARSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRY
                     APRMLRCLKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDT
                     RLWEVAVLFHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLA
                     DRKARLTIALKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPS
                     VRITDMLLEVDAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTH
                     DYWQLSRLARWHVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGE
                     AMNMVNAKYGSVPGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVRE
                     QYADTAGFTDHLFGASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKARED
                     LIVANWPDIFRCAATMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEW
                     ILDTDMQRRAQIGLNKGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVII
                     YWNTVHLGHAVTERRNEGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
     gene            complement(4271..4672)
                     /gene="pemK"
                     /locus_tag="LSX49_004439"
     CDS             complement(4271..4672)
                     /gene="pemK"
                     /locus_tag="LSX49_004439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001398199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin
                     endoribonuclease PemK"
                     /protein_id="HBL7170752.1"
                     /translation="MLKYQLKNENGWMHRRLVRRKSDMERGEIWLVSLDPTAGHEQQG
                     TRPVLIVTPAAFNRVTRLPVVVPVTSGGNFARTAGFAVSLDGVGIRTTGVVRCDQPRT
                     IDMKARGGKRLERVPETIMNEVLGRLSTILT"
     gene            complement(4605..4862)
                     /gene="pemI"
                     /locus_tag="LSX49_004440"
     CDS             complement(4605..4862)
                     /gene="pemI"
                     /locus_tag="LSX49_004440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PemI"
                     /protein_id="HBL7170753.1"
                     /translation="MHTTRLKRVGGSVMLTVPPALLNALSLGTDNEVGMVIDNGRLIV
                     EPYRRPQYSLAELLAQCDPNAEISAEEREWLDAPATGQEEI"
     gene            complement(4955..5608)
                     /locus_tag="LSX49_004441"
     CDS             complement(4955..5608)
                     /locus_tag="LSX49_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001757010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL7170754.1"
                     /translation="MIQTRNQYLQFMLVMLAAWGISWGARFVMEQAVLLYGSGKNYLF
                     FSHGTVLMYLLCVFLVYRRWIAPLPVVGQLRNVGVPWLVGAMAVVYVGVFLLGKALAL
                     PAEPFMTKLFADKSIPDVILTLLTIFILAPLNEETLFRGIMLNVFRSRYCWTMWLGAL
                     ITSLLFVAAHSQYQNLLTLAELFLVGLITSVARIRSGGLLLPVLLHMEATTLGLLFG"
     gene            complement(6547..7404)
                     /gene="repA"
                     /locus_tag="LSX49_004442"
     CDS             complement(6547..7404)
                     /gene="repA"
                     /locus_tag="LSX49_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HBL7170755.1"
                     /translation="MTDLQQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFTSR
                     FDFAIHVAHARSKGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDV
                     SEEAVAAARRSRVEWENRQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIK
                     RARARRDANRERQDIVTLVKRQLTREISEGRFSASREAVKREVERRVKERMILSRNRN
                     YSRLATASP"
     gene            complement(7397..7471)
                     /gene="tap"
                     /locus_tag="LSX49_004443"
     CDS             complement(7397..7471)
                     /gene="tap"
                     /locus_tag="LSX49_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HBL7170756.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
     gene            complement(7706..7963)
                     /gene="repA"
                     /locus_tag="LSX49_004444"
     CDS             complement(7706..7963)
                     /gene="repA"
                     /locus_tag="LSX49_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HBL7170757.1"
                     /translation="MSQTENAVTSSSGAKRAYRKGKPLSEAERQRAASARKRSVCKEI
                     KVFVRPELKNCLTSLCAEEGVTQAELIERLIEKEACHRNMM"
     gene            8368..9390
                     /locus_tag="LSX49_004445"
     CDS             8368..9390
                     /locus_tag="LSX49_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL7170758.1"
                     /translation="MTITTIGIDLAKNVFAVHGVDQNGKTVLVKSRVTRAALPGLIAS
                     LPPCVIGMEACSGAYYWARLFLQYGHEPRLMAAKFVSPYRMAGKSGKNDAADAQAICE
                     AVRRPHMRFVPVKDESQQAMQCLHRNRQGFIEEKTATYNRLRGLISEFGVIAPQSTDA
                     LRHMVSAQKSSLPLQVQQCVDDLLEHVDRIEANITEYDRILSRIAKTDHRSQRLMKLK
                     GVGPTTACALVACIGNAHDFKNGRQLAAWLGLTPSQYSSGGKSKLGRITKAGDSYLRT
                     LLVQGARSVLIGAEKRTDLFSRWVCSLVERRGYWRAVVAIAAKNARLCWASLHYGDDF
                     RLYSAS"
     gene            9862..10215
                     /locus_tag="LSX49_004446"
     CDS             9862..10215
                     /locus_tag="LSX49_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170759.1"
                     /translation="MSETVQIESFNAEFLTKQKLHDLIFYRKSFDITNVNDISETVKI
                     VEYVIEHQQKKLTCRVYTEYRSTAVAGSLWSPTALLGAVSAAAIGVHNLATWNPDYEI
                     GKNYVKRTISVRYKK"
     gene            complement(10628..11206)
                     /locus_tag="LSX49_004447"
     CDS             complement(10628..11206)
                     /locus_tag="LSX49_004447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="HBL7170760.1"
                     /translation="MSKLAASPIAALLIRIILRSVNQHSPLLMQLHAAGIRTGDAERI
                     LSSGECWQRQKTLLTGREVSFMKGLFRIVDMKRWYLCPQVRVADIVQLNGNIRPRSRQ
                     WWQLFRMVSQWHVDVVIVERRSFSIVAAVELDDASHLRPERRRRDILLEEVLRQAGIP
                     LLRSHDARKLLQMTGEWLNTTGADQQSPEHRS"
     gene            11239..>11299
                     /locus_tag="LSX49_004448"
     CDS             11239..>11299
                     /locus_tag="LSX49_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170761.1"
                     /translation="MASVSISCPSCSATDGVVRN"
BASE COUNT         2716 a         3009 c         2908 g         2666 t
ORIGIN      
        1 ttcgacgact acctgctgcc ggccgagaag ttcgccgcac tcaagcgcga gcaggccctg
       61 cccctggcga tcaacccgaa cagcgaccag tacctggaag agcgtttgca gctgctggac
      121 gagcagttgg ccaccgtcac ccgcctggcc aaggacaacg agctgcccga tgccatcctc
      181 accgagtcag ggctgaaaat caccccgctg gatgcggcgg tgccggatcg ggcgcaggcg
      241 ctgatcgacc aaaccagcca gttactgccg cgcatcaaga tcaccgaact gctgatggac
      301 gtggacgact ggacgggctt cagccgccac ttcacccact tgaaggacgg ggccgaggcc
      361 aaagacagga cgttgctgct gtccgcaatc ctcggtgatg cgatcaacct cgggctgacc
      421 aagatggccg agtcgagccc cggcctgacc tacgccaagc tgtcctggct gcaagcctgg
      481 cacatccgcg acgaaaccta ttcggggtcg gttccggctg agggcgaaat gacaccctaa
      541 gcgttagctc tgtgtcgttg cacgatgtca gcgacggtat tcttgctgat accgagctcg
      601 cgtgcgatcc agcgatagct gcgtccctcg gccctcatcg caaccacctt aggcaaaagt
      661 cggtctgatt ttggtcgcac tccggcctga cgaccaagcc tcttaccacg tgccttcgca
      721 acagcaaggc ctgacttgac ccgctcgctg atgagatccc gctcaaactc cgcaatgccg
      781 gaaagaaacg tcgccagcat tcgtccatac ggcgacgaaa gatcgaacgc cattccattc
      841 atggctatca cggaaacctt ccagttctcc agttcacgta gcgtattgag cagatcgagc
      901 gtcgagcgcc cccaccggga aagctcagtg accaggattg catcaatttg tctggactgg
      961 gcaagcgcca ggactttctt tcgctcggcc cggtcgagtt tagttcctga acctgtttcc
     1021 ttaaatattc ccaccacgtc gtagccggca cagccggcga aggctcgcag atcaaattcc
     1081 tggcgttcac aagactgatc cgctgttgaa acccggcagt aaatggcggc acgatgtccc
     1141 aattgaaccc tcctggattt ttgtatcgga acgccctgat ttatatgggc tggctgttgt
     1201 ccaaaacaga ctatacttca aaagggacga atttgtatgt cacgacgcca tattttcacc
     1261 gaacggcagc gagcagcgct gttcgatctg cccacggacg aactgtcgct actgaagttc
     1321 tacacgctgg gcgatgatga cctggaaaac attaggcagc gccgcagacc ggaaaacagg
     1381 attggctttg ccctgcaact ttgtgcctta cgatatccgg gccgtgcact ggctcctggt
     1441 gagatgatcc cgcgtgaagt cctttccttc gtcggtgctc agcttggagt tccggctgat
     1501 gcgcttctca cttatgccac acggcgccaa acccgtcagc agcacatgga cacgctgcgc
     1561 gaaatttacg gctacaagac cttcacgggc cgtggtgccc gtgatctgcg ggagtggact
     1621 ttcggccagg ccgaagatgc cagatcaaac gaggatcttg ctcatcgttt tattgtgcgg
     1681 tgtcgggaaa cttccaccat tctgcccgca gtatcgacaa tcgagcgctt gtgcgcggat
     1741 gctctggtcg ccgctgagcg gcggattgaa acgcggattg cggaaaattt aacagcggat
     1801 gttcgcgatc acctggacaa acttctgagt gaaatgctcg ccggcaatat cagtcgtttc
     1861 atctggcttc gcaacttcga ggttggtaac aactcggctg ctgctaaccg tttgctcgac
     1921 aggctcgaat ttctgcgtac cctgaatatc aatcatagtg ctttggccag catacctgcc
     1981 catcgcattg cccggctgcg tcggcagggt gaacgctact tcaccgacgg tttgcgtgac
     2041 atcacttcgg accgccgctg ggcgatcctt gccgtctgtg ttgtggagtg ggaagcggcg
     2101 attgctgatg ccatagtcga aacccatgac aggatcgtag gaaaaacctg gcgggaagcg
     2161 aagcgccagc atgacgaaac aatttccggc tctaaagcca cactcacgga tacgatccgt
     2221 accttcaccg cgctgggagc ttcgttgctt gaggcccgca gtgacggaac cccgctggag
     2281 atggctgtcg ccagttcggt tgcatgggac cggctcgctc aactggtagc gacagggact
     2341 caactcagca acacgctagc cgatgagcct cttgcatatg tcgggcaggg ataccatcgc
     2401 tttcgtcgtt atgcgccccg catgttgcgc tgtctgaagc tcgaagccgc gccggtcgcc
     2461 ggaccattgg tagcagcagc tttgtcgatc ggagagatga aaggtgttgc atcgccagaa
     2521 aggcgtttcc tgcggcccag ctccaaatgg aaccgtcatt tacgagctca ggaaaaagga
     2581 gatacccgtc tttgggaagt ggcggtactc tttcacctcc gggatgcttt tcgttccgga
     2641 gatgtctggc tcgctcattc gcgccgctat ggtgacctca agcaggtact ggtgccgatg
     2701 atcgcggcgc aggaaaatgc aaaactggcc gtgccttcca acccacagga ttggctggca
     2761 gacagaaagg cgcgactcac gatcgctctt aagcggctgg cccgggctgc ccgtaacggc
     2821 actattccgc acggtagcat agaagatgga acgttgcgga tcgacaggtt gacagcagac
     2881 gtgccggatg gtgccgaggc actcatactg gatctgtatc gccgaatgcc gtccgttcgg
     2941 attaccgaca tgctgcttga agttgatgca gcccttggtt tcacagatgc gtttacccat
     3001 ctgagaaccg gggctccatg tcgcgaccgg atcggtctgc tcaacgtcct gctcgctgaa
     3061 gggctcaatc tgggcctgcg taagatggcg gaagctacaa acacgcatga ttactggcag
     3121 ctctcacgcc ttgcccgctg gcatgttgaa agcgaagcca tgaaccaggc attggcaatt
     3181 gtggtggccg cgcagggtaa actgccgatg tcacgcgtct gggggatggg cacgtcagca
     3241 tcgagcgatg gtcagttttt cccgacagcg cggcatggcg aagccatgaa catggtcaat
     3301 gccaaatatg gttctgttcc cggcctcaaa gcgtatactc acgtaagcga ccagttcgcg
     3361 ccattcgctt gtcagtcgat cccggcgacc gtgagcgagg caccgtatat tctcgatgga
     3421 ctactgatga acgaggtcgg tcgccatgtt cgcgaacagt atgccgatac agcaggattc
     3481 accgaccatt tgttcggagc cagtagcctg ctcggctaca atctcgttct gcgaatcagg
     3541 gatctgccat cgaagcggtt gtacgtattt aatcccgata cgacccccag ggagttacgc
     3601 aagttggtag gtggaaaagc ccgggaggat cttatcgttg cgaactggcc tgatattttc
     3661 cgttgtgccg cgacgatgac cgctggcaaa atcaggccca gccaactcct gcgcaagctc
     3721 gcttcttacc cacgacaaaa caaccttgca gttgcgcttc gtgaagttgg tcgtattgaa
     3781 cggacccttt tcattattga gtggatcctg gatacggaca tgcagcggcg tgctcagatc
     3841 ggtcttaaca agggagaggc ccaccatgcg ctcaaaaatg cgctccgtat cgggaggcag
     3901 ggggaaattc gcgatcgcac gacagagggg cagcactacc gaatcgctgg gctcaattta
     3961 ttgactgcgg tgatcattta ctggaatacc gtccatcttg gtcatgccgt cacggagcgg
     4021 cggaacgaag ggttggatgt tccccctgaa tttcttcccc acatatcccc attgggctgg
     4081 gcgcacattc tactgactgg cgaatatctt tggcccaagg aaccgaaagc ttagggtgtc
     4141 atttcgccct cagccggaac cgaccccttt tagccaaata acgtttggga atcaccagaa
     4201 tggtgggaca acagcggttt tagtgcccta aatcgtacgt tttcatccag ttgcccctca
     4261 aaccccatgt tcaagtcaga atagtggaca ggcggccaag aacttcgttc atgatagtct
     4321 ccggaacccg ttcgagtcgt tttccgcccc gtgctttcat atcaattgtc cggggttgat
     4381 cgcaacgtac aacacctgtg gtacgtatgc caacaccatc caacgacacc gcaaagccgg
     4441 cagtgcgggc aaaattgcct ccgctggtta cgggcacaac aacaggcagg cgggtcacgc
     4501 gattaaaggc cgccggtgtg acaatcagca ccggccgcgt tccctgctgc tcatgacctg
     4561 cggtaggatc aagcgagaca agccagattt cccctctttc catgtcagat ttcctcctga
     4621 ccagtcgccg gtgcatccag ccattctcgt tcttcagctg atatttcagc attcggatca
     4681 cactgtgcca gtagctcagc cagtgaatat tgcgggcgtc tgtacggctc aacaatcagc
     4741 cggccattat caatgaccat gccaacttca ttatctgtgc ccagagacag cgcattcagc
     4801 agtgccggtg ggacggtcag cataactgag ccgccaaccc tcttcagtcg ggtggtatgc
     4861 attcttcacc tccataaaag ttatatttaa atataacatc cactaaaaaa acacaccagg
     4921 ctttaacgca caatgtttaa taaaaatata actttcaacc aaacagtaaa cccagcgtgg
     4981 ttgcttccat atgcagcaat accggcagca gcaggccacc acttctgatc ctggccactg
     5041 atgtaatcaa ccccaccagg aacagttctg ccagtgtcag caggttctga tactggctgt
     5101 gcgcggcgac gaacaacaac gacgttatca gcgcccccag ccacatcgtc cagcagtacc
     5161 gtgaacggaa gacgttcagc ataatccccc ggaacagcgt ttcctcattc aacggggcaa
     5221 ggataaagat ggtcagcaac gtcaggatca cgtcaggtat ggacttatcg gcaaaaagtt
     5281 tcgtcataaa tggctcagca ggcagagcca gcgccttacc gagcagaaat acaccgacat
     5341 acaccacggc catcgcaccg accagccacg gtacgccaac gttgcgcagc tgaccaacga
     5401 ccggtagcgg agctatccaa cggcggtata ccaggaaaac acacagcagg tacatcagaa
     5461 cagtaccatg actgaagaac aaatagtttt ttcctgatcc ataaagcaga acggcctgct
     5521 ccatgacaaa tctggctccc caactaatgc cccatgcagc cagcataacc agcataaact
     5581 gcagatattg attacgtgtt tgaatcattg catcgcctgt aaatttttaa cttgtcctat
     5641 ttttgtcatt accacgtata tacacatgta taacaattca gatatcgtta ccaggatatg
     5701 ccgcatcagc ggcatggaag gcggcactct gttgtttcat atgatacagg agtaaaaccg
     5761 ccgaagcccg gcgtaagccg gtactgattg atagatttca ccttacccat ccccagccct
     5821 gccagaccat acccgctttc agccatgaga gagcttctgt gcgcggtcgg agtggtcccg
     5881 acgagggttt acccgaagtc ggggcgtatc tccgcgttag cgggccgtga gggccgctta
     5941 cgagcgtgta ctgagaactt ccagcgagaa gactgacagc gatgaagatg tagttacaac
     6001 attcataatt aaaagcgact ctgttccggc ccgaagggcc ggggcggggc cgcttttcag
     6061 ttatgaggga ggggctttgt ggtttcagtt ctgcgctgga ccggggtttt tctggaggtt
     6121 gtttttgtgt gttgtaacta aagtggctcc ggtcggggcc cgccgcttgc ggtgggaggt
     6181 gcatatctgt ctgtccacag gacaggcagt gaataggttt tctttttaaa tgaatgtaat
     6241 taagtagttt aaaggagata taaacaggtg tttaaaagat acattgcacc ctgtaagact
     6301 ggcggctggc gctttatgac atgaacggtt gtaaccttat ggggaagtcc cttgcagtta
     6361 aatgtggata agcaaaattc cccgtcgctg aggcgtattt tgtattaaaa acagggggaa
     6421 tcggatgctc cagaaggtgg atgatgagat tgttttttgc atgcgacgct gtttttttgt
     6481 gcaccggcgg gcttcaggcg tgcggatgcc tccggcgcag gccggattat tctgaggaga
     6541 tcactttcag ggggaagcgg tggccagccg gctgtaattg cggttacgtg acagaatcat
     6601 gcgctccttc acacgacgct ccacttcacg ttttaccgcc tcacgactgg cagagaagcg
     6661 cccttccgag atttcacgcg tcagctgccg tttcaccagg gtgacgatat cctgacgttc
     6721 cctgttcgca tcacgacgcg cacgggcacg ctttattccc cgggacttaa gctctgtctg
     6781 gtaactgcgg aaacgctcac ggacaaaacg ccaggctttc gctatcagtt catccatacc
     6841 cagggtatcc agcccctgct ttttgcgctg tctgttttcc cattccacac ggctgcggcg
     6901 cgcggcggcc actgcctcct ctgatacatc gagggcagca aacagtgcag atgtgaacgt
     6961 gatatcggtc ggaatgtagc acccgataag cgggtcatat tccgtctggt aggtaatcag
     7021 tcccagctct gacaggaacg tcagagcccg ggtggcacgg gtgatggaga gttttcctgc
     7081 accggactct gtcgccagcc cgcactcaat ggccagcgtg gtgatggagc actggacacg
     7141 gttggccagc gggtcatagt ggaaacacag cccctgcagc agcgcatcaa tagcccgtcg
     7201 acgcagcacc ggtggcatgc gccgacgcag tcccttcgaa cgggcatgcg ccacatgaat
     7261 agcgaaatca aaacgggagg tgaagcccac cgccttttcc atcagttttt cgcagaactt
     7321 cagcgttcct gcaccttcac ggggtgtaaa caccggattc gggttcttta cctggcggta
     7381 atacgtttgt tgaagatcag tcacaccatc ctgcgcttac aatgcgcaga aggagtgagc
     7441 acagaaagaa gtcttgaact tttccgggca tataactata ctccccgcat agctgaattg
     7501 ttggctatac ggtttaagtg ggccccggta atcttctctt agtcgccaaa cctggtgaag
     7561 gttatcgggg tttttgcttt tctggctcct gtaaatccac atcagaacca gttccctgcc
     7621 accttacggc gtggccagcc acaaaattcc ttaaacgatc agtaatctag cactgacaga
     7681 aaaaactagc aagaatgtga ccccatcaca tcatgttccg gtgacaggcc tctttctcga
     7741 taagcctttc tatcaactct gcctgagtta ccccttcctc tgcacacaga ctggtaaggc
     7801 agtttttcag ttctggtctg acgaaaacct tgatctcttt acatacagat cgtttgcgcg
     7861 cagaagctgc tctctgtcgt tctgcttcac tcaaaggttt accctttctg tatgctcgtt
     7921 ttgcaccaga tgaggaagtc actgcatttt ctgtctgcga catctcgcct cctcaatact
     7981 caaacaggga tcgtttcgca gagaatacta cagttttttg aaatcagcga cttgagaatt
     8041 gtgacgaaga tctgtgttgg cgcacaaatc aacggggatt actgtcgttt aagggctgcg
     8101 tttgggaaac gtacaatatt gtacggttgc gttatcgcgc tcggacgcta tacggtgttt
     8161 ggcagacctt tagggacatg agataaccta aatgcgataa gagaaaagca ataacttaaa
     8221 ggcgatagct gatcacgatg aatcaatcag ttacttatca gtatcggtta aaaaatgccc
     8281 ctaacgaatg gaagggactt cccctggata tgcacctgat taactcttgt gcaatcatgg
     8341 ggtaaacata gcctggagag attcgttatg accatcacta ctatcggtat cgatcttgct
     8401 aaaaatgtgt tcgctgttca tggggttgac caaaatggca aaaccgttct ggtgaaatcc
     8461 agagtaaccc gcgcagctct tcccgggctg attgcaagtt taccgccctg tgttatcggg
     8521 atggaggcgt gctccggggc ttattactgg gcaagattgt ttctgcaata tggtcatgag
     8581 ccgcgtctga tggccgctaa atttgtatct ccataccgca tggccggtaa atcagggaaa
     8641 aatgatgcag ctgatgctca ggctatctgc gaagcggttc gtcgcccaca tatgcggttt
     8701 gttccagtta aggacgagag ccagcaggcg atgcagtgtc tgcatcgtaa ccgacagggt
     8761 tttatcgaag agaaaacagc aacatataat cgtcttcgag ggttgatatc agaattcggc
     8821 gtcattgccc cacaaagtac agatgctttg cggcacatgg tttctgcgca gaagagctct
     8881 ttacctcttc aggttcagca atgtgtagat gatttactgg aacacgttga tcgcattgaa
     8941 gctaacatca ctgaatatga ccgaattttg tcccgcatag ccaaaacaga tcaccgcagt
     9001 cagcggctga tgaagctaaa aggagttggt cccacaactg cctgtgctct ggttgcctgt
     9061 atcggtaatg cacatgattt taaaaatgga cggcaactgg cggcctggct ggggttgact
     9121 ccatcgcaat acagtagcgg cggaaagtcg aagttaggca ggataacaaa agccggtgat
     9181 tcgtatctgc gaacgcttct ggtacagggg gctcgttcag tactgattgg cgctgagaaa
     9241 aggactgact tattcagtcg ttgggtctgt tcactggtcg aacgcagagg atactggcgc
     9301 gctgttgtgg ccatcgccgc caaaaatgca aggctgtgct gggcatcatt gcattacggt
     9361 gatgatttca ggctgtattc agcaagctaa agcaggaaga aaccgtatga ccatctgatc
     9421 tgcaactcgt tgatgataaa gggttagacc ccgtgaggta tatctgatta ttgtacagga
     9481 tatacgtatc cgcttaacga acaagagcct cacgcgcgtc tttcatcagg gtccgaatcg
     9541 atagcgattc attatggccg tttatagtac cgcagtctct cccctttatt tttaactgta
     9601 gtgcagacac aaaccataaa taccgacgtt gactgttcgg ggaagccctt atagtacaaa
     9661 aatgtccgat ctccaaaccg cccccacata cggcagtcgg tttacgctta cagttaagac
     9721 gatcaatttc ttattattga tcgtttatac aagtcaatat attcttttct gacatacact
     9781 gcccctgaaa aagtgcaacg tttgaccgta aggcgcgtgc ctagggaaat tcacagactc
     9841 caagaaagag aggaacaacg gatgtcagaa acggtacaga ttgagtcgtt caacgcagaa
     9901 tttttgacca aacagaaact acacgacctg attttttacc gcaaaagttt tgatatcacg
     9961 aatgttaacg acatcagtga aaccgtcaaa atagtggagt atgtgattga acatcagcag
    10021 aagaaattaa cctgccgcgt atacaccgaa tacagaagca ctgcggtggc aggctcccta
    10081 tggtcaccaa cagcacttct gggagctgtg agtgctgccg caatcggtgt ccataatctg
    10141 gcgacatgga acccggacta tgaaattggt aagaattacg tcaaaagaac catatctgta
    10201 aggtataaaa agtaacgggt ttatatctgt ccggttcagc caaaatcctc tcccataatt
    10261 cctatgcgag ctgaacgggg gcagtctgga gatcgaaaaa ttttgaacgt taagcgcatt
    10321 atttaaccaa tagatatgca taacagattg attttgcgtc aacgtctatc ccttttaagt
    10381 tatcgccatt gcagtattgc atttaggtta tccgattgag gtcaaatcct ctgaaaacgc
    10441 cgtatagcac gggagtacac ccgagcgcga taacgcaacc gtacaatatt gtacgtttcc
    10501 caaacgcagc cctttaatgt gatttaaact gtgaaatagt atggttttca gttatggaaa
    10561 cgccgggagc ggggaaaact tgctttttcc cgtttccggg gttggacaac tgagcaacgc
    10621 gaaggcgtca gctacgatgt tccggggact gctgatcagc ccctgttgta ttcagccatt
    10681 ctccggtcat ctgcagcagt tttctggcat cgtggcttct gagcaacgga ataccagcct
    10741 gcctcagaac ctcttccaga agaatatccc ggcgtctgcg ttccggtcgt aaatgactgg
    10801 catcatccag ctctactgct gcaacaatac tgaacgaacg ccgctcaacg ataaccacat
    10861 caacatgcca ctgagacacc atcctgaata actgccacca ctggcgtgat cgtggccgga
    10921 tattcccgtt cagctggacg atatccgcga cccgtacctg cggacacaga taccaccgct
    10981 tcatatccac aattctgaac agtcctttca taaaactgac ttcccttcct gtcagcagcg
    11041 tcttctgacg ttgccagcat tcaccgctgg acagtattcg ctctgcatca ccggtccgta
    11101 tacctgccgc atgcaattgc atcagcaaag gagaatgctg atttacactt ctgaggataa
    11161 tccggataag taacgctgca ataggtgatg ctgccaactt actgatttag tgtatgatgg
    11221 tgtttttgag gtgctccagt ggcttctgtt tctatcagct gtccctcctg ttcagctact
    11281 gacggggtgg tgcgtaacg
//
LOCUS       DAFGPF010000143        11151 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFGPF010000143 DAFGPF010000000
VERSION     DAFGPF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11151
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.143"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            209..313
                     /locus_tag="LSX49_004449"
     CDS             209..313
                     /locus_tag="LSX49_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2618 domain-containing protein"
                     /protein_id="HBL7170762.1"
                     /translation="MENNNRLMPHIRRTTHIMKFAHRNSFDFHFFNAR"
     gene            623..2821
                     /gene="speF"
                     /locus_tag="LSX49_004450"
     CDS             623..2821
                     /gene="speF"
                     /locus_tag="LSX49_004450"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase SpeF"
                     /protein_id="HBL7170763.1"
                     /translation="MSELKIAVSRSCPDCFSTHRECVNIDKSNYIDVAAIILSVNDVE
                     HGKLDEIDATGYGIPVFIATENEERVPAEYLPRISGVFEHCESRKEFYGRQLETAASH
                     YETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
                     NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVL
                     FDRNNHKSNHHGALLQAGATPVYLETARNPYGFIGGIDAHCFEESYLRELITEVAPQR
                     AKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCS
                     PLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMH
                     ASTSPFYPLFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELV
                     DGKPWQSYETAQIAVDLRFFKFVPGEHWHSFEGYAENQYFVDPCKLLLTTPGIDARNG
                     EYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVRFEKLL
                     EADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRV
                     SMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFS
                     ALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRDAQSALLKGEKL"
     gene            2818..4137
                     /gene="potE"
                     /locus_tag="LSX49_004451"
     CDS             2818..4137
                     /gene="potE"
                     /locus_tag="LSX49_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HBL7170764.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQS
                     GLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            complement(4194..5834)
                     /gene="pgm"
                     /locus_tag="LSX49_004452"
     CDS             complement(4194..5834)
                     /gene="pgm"
                     /locus_tag="LSX49_004452"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HBL7170765.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAISNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALLADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(5860..6405)
                     /gene="seqA"
                     /locus_tag="LSX49_004453"
     CDS             complement(5860..6405)
                     /gene="seqA"
                     /locus_tag="LSX49_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HBL7170766.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFTAASQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVCGTI"
     gene            6590..7354
                     /gene="ybfF"
                     /locus_tag="LSX49_004454"
     CDS             6590..7354
                     /gene="ybfF"
                     /locus_tag="LSX49_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL7170767.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALA
                     PDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPTLFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            7494..7787
                     /gene="ybfE"
                     /locus_tag="LSX49_004455"
     CDS             7494..7787
                     /gene="ybfE"
                     /locus_tag="LSX49_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HBL7170768.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV"
     gene            7927..8457
                     /gene="fldA"
                     /locus_tag="LSX49_004456"
     CDS             7927..8457
                     /gene="fldA"
                     /locus_tag="LSX49_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HBL7170769.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            8667..8753
                     /gene="uof"
                     /locus_tag="LSX49_004457"
     CDS             8667..8753
                     /gene="uof"
                     /locus_tag="LSX49_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HBL7170770.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            8746..9192
                     /gene="fur"
                     /locus_tag="LSX49_004458"
     CDS             8746..9192
                     /gene="fur"
                     /locus_tag="LSX49_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HBL7170771.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(9276..9602)
                     /locus_tag="LSX49_004459"
     CDS             complement(9276..9602)
                     /locus_tag="LSX49_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170772.1"
                     /translation="MKKLILIAMMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFAEQESVRVLDYQQCIQATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(9652..11058)
                     /gene="chiP"
                     /locus_tag="LSX49_004460"
     CDS             complement(9652..11058)
                     /gene="chiP"
                     /locus_tag="LSX49_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HBL7170773.1"
                     /translation="MRAFSGKRSTLALAIAGVTAMSGFMAIPEARAEGFIDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSLGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSANDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
BASE COUNT         2722 a         2772 c         2755 g         2902 t
ORIGIN      
        1 atttggcagg tttaatttct taatgaaaat acaacccaca aaattgcaac atttaaacaa
       61 caaaacagca tctaatatgg cgctattcat cattaatgat ttattatttg ggatatgatc
      121 gttttttgtt gatcttcttc acagattata gccatttcat ggatagaata accctacctt
      181 caactgacac agaaaaaggt aaaggtaaat ggaaaataat aaccgcttaa tgcctcatat
      241 aaggcggaca acccatatca tgaagtttgc ccatcgtaat agttttgact ttcatttttt
      301 taatgcccgc tagtcttctg actaaagggc accccagcgt acaggtctcc ctgactttaa
      361 gcattacagg ttaatacctg tatccctcgg tgctcatata ctgctaaccc ttttaaactc
      421 taaataattc gagtcgcagc acatgcaact tgaagtatga cgagtatagc cagttaccgg
      481 gctggtctgg gttattgcat ctgcaaaaag caaactactg atttatttat cagcggtggg
      541 gttttgcttt tttccggcgt gatcaatttc tcctttgaga aattgaggac ctgctattac
      601 ctgaaataaa gagatgaaca aaatgtcaga attaaaaatt gccgttagcc gttcttgccc
      661 ggattgtttt tccactcatc gtgaatgcgt gaatattgac aaaagtaatt atattgacgt
      721 tgccgccatt attttatcag tcaatgatgt tgaacatgga aaactcgatg aaatagacgc
      781 tactggctat ggcattcctg tttttattgc aacggaaaat gaagaacgtg taccagcaga
      841 atatctgcca cgtatttctg gtgtcttcga gcattgcgaa tcacggaaag agttttatgg
      901 acgtcagtta gaaaccgctg ccagccatta tgaaacgcaa ctgcgcccgc ccttcttccg
      961 cgcactggtc gattatgtca atcagggcaa tagcgctttt gactgcccgg gtcatcaggg
     1021 aggtgagttt ttccgtcgcc atccggcagg caatcagttc gtggaatatt ttggcgaaat
     1081 gctcttccgc tccgacttgt gtaatgccga cgttgcaatg ggcgatctac tgattcatga
     1141 aggtgcgcca tgcattgcac agcaacatgc ggctaaagtg tttaatgccg ataaaacgta
     1201 ctttgtttta aacggcacat cctcctccaa caaagtggtt ttaaacgccc tgctgacacc
     1261 gggtgatctg gtgctgtttg accgtaataa ccataagtct aaccaccacg gagcgttgct
     1321 acaggctggt gcaacaccgg tttatctgga aacagcacgt aacccgtatg gttttatcgg
     1381 tggcattgat gcgcactgct tcgaagaaag ttatctgcgt gaactgatta cagaagttgc
     1441 accgcaacgg gcaaaagagg cgcgtccgtt ccgcctcgct gtgattcagt taggcaccta
     1501 cgacggtact atttataacg cccgccaggt ggtggataaa atcggccatc tgtgtgacta
     1561 catcctgttt gactccgcat gggtcggcta tgaacagttt attccgatga tggcggactg
     1621 ttcgccgctg ctactggagc ttaatgagaa cgatccgggt attctggtta cgcaatctgt
     1681 gcataaacaa caggctggtt tttctcagac ttcacaaatt cataaaaaag acagccatat
     1741 caaagggcaa cagcgttatg taccgcacaa acgcatgaac aacgccttta tgatgcacgc
     1801 ctccaccagc ccgttctatc cgctgtttgc cgcactggat atcaacgcca aaatgcatga
     1861 aggtgtcagc ggtcgtaata tgtggatgga ttgtgtggtt aacggtatta atgcccgcaa
     1921 attgatcctc gataactgcc agcacattcg cccgttcgtt cctgaactgg tggatggtaa
     1981 accctggcag tcgtatgaaa cagcgcaaat tgcggttgat ctgcgcttct ttaaatttgt
     2041 acccggtgag cactggcatt cttttgaagg ctacgcagag aaccaatact ttgtcgatcc
     2101 gtgcaaactg ttgctgacaa ctccaggtat tgatgcacgt aacggcgaat atgaagcgtt
     2161 cggtgtaccc gcaacgattc ttgctaactt cctgcgcgaa aatggcgtag tgccggaaaa
     2221 atgcgatctt aactccatcc tcttcctgct gactccggca gaagatatgg ccaaactgca
     2281 gcaacttgtt gccctgctgg tacgcttcga aaaactactg gaagctgatg cgcctctggc
     2341 ggaagtactg ccttccatct acaaacagca tgaagagcgc tacgccggtt ataccctgcg
     2401 tcagttgtgc caggaaatgc atgatttgta tgcccgtcac aacgtgaaac aactgcaaaa
     2461 agagatgttc cgtaaggaac acttccctcg cgtcagcatg aatccgcaag aagccaacta
     2521 cgcctactta cgcggtgaag tggagctggt tcgtctgccg gatgcagaag gccgtatcgc
     2581 tgccgaaggt gcgcttcctt atcctccggg tgtgctgtgt gttgttcctg gtgaaatctg
     2641 gggtggtgct gttctgcgtt acttcagcgc tctggaagaa ggcatcaacc tgctgccagg
     2701 ttttgcaccg gagctgcagg gtgtctatat cgaagaacat gatggtcgta agcaagtttg
     2761 gtgctatgtc atcaagcctc gtgatgcgca aagcgccctg ttgaaagggg aaaaattatg
     2821 agtcaggcga aatcgaacaa aatgggtgtc gttcagttaa ccatactgac gatggtcaac
     2881 atgatgggct ccggtatcat catgctgccg acaaagcttg ccgaagtcgg gacaatctca
     2941 attatctcct ggctggtgac agccgtaggc tcaatggcac tggcatgggc attcgcaaaa
     3001 tgcggtatgt tcagccgtaa atcaggaggt atgggcggtt atgccgagta tgctttcggt
     3061 aaatccggta actttatggc gaactatacc tacggcgtct cgctgctgat tgctaacgtc
     3121 gcgattgcta tttcggcggt tggttacggc accgaactgc tcggcgcgag tttgtcgcca
     3181 gtgcagattg gtcttgcgac catcggggtg ctgtggattt gtaccgtggc taactttggt
     3241 ggtgcgcgca ttaccgggca aatcagtagc attaccgtgt ggggggtcat tattccggtg
     3301 gtaggcctgt gcattatcgg ctggttctgg tttagcccga cgctttacgt tgattcctgg
     3361 aatccgcatc atgcaccctt cttcagtgcg gtaggttctt ccatcgctat gacgctgtgg
     3421 gcttttcttg gtctggagtc tgcgtgtgcg aatactgatg tagtggaaaa cccggaacgt
     3481 aatgtgccaa tcgcggtact cggcggtacg ttaggtgcgg cggtgattta tatcgtctcc
     3541 accaacgtga ttgccgggat tgtgccaaat atggagctgg caaattcaac ggcaccattt
     3601 ggtctggcct tcgcgcagat gttcacgccg gaagtgggta aagtcattat ggcgctgatg
     3661 gtgatgtcct gctgcggttc gctgcttggc tggcagttca ccattgccca ggtgtttaaa
     3721 tcttcatctg atgaaggcta cttccctaaa attttctccc gtgtaaccaa agtggatgca
     3781 ccggtgcagg gaatgttgac cattgtgatt atccagagcg ggttggcgct gatgacgatt
     3841 agcccgtcgc taaacagtca gttcaacgtg ctggttaacc tggccgtggt gactaatatc
     3901 attccgtata ttctgtcaat ggcggcatta gtcattattc agaaggtcgc taatgtgccc
     3961 ccctcaaaag cgaaagttgc aaactttgtt gcttttgttg gcgcgatgta cagcttttat
     4021 gcgctgtact catccgggga agaagccatg ctatacggtt ccatcgtgac cttcctcggt
     4081 tggacactgt atggtctggt ctcaccacgc tttgaactga aaaataaaca cggttaatta
     4141 agcaaagcaa aaaagggcga tcttccgacc gccctttttc ttatttgata tgtttacgcg
     4201 tttttcagaa cttcgctaac aatttcaacc gcttctttct caatctgctt gcgatgttct
     4261 tcaccaagga agctttcgca gtagatctta tatgcgtctt ccgtgcctga cggacgcgcg
     4321 gcgaaccagc cgttgtcagt catcactttc agaccgccga tagaagcgcc attacccggt
     4381 gccgccgtca gacgcgcggt gatcgggtca cctgccaggg tgctggcgct caccatttcc
     4441 ggagacagct tagacaacgc cgctttttgt gcggaagtcg ctgctgcctg caaacggtta
     4501 tagctcggcg caccaaagcg ttttgccagt tcgttatagt gttcctgcgg gttcttaccg
     4561 gtgacagcgg tgatttccgc cgccagcaga cacataatga tgccgtcttt atcggtggac
     4621 cacggcgtgc cgtcgaaacg caggaaggaa gcccctgcgc tctcttcgcc gccaaagccg
     4681 aagctgccgt cgaacagacc atcaacaaac catttgaaac ctaccgggac ttctaccagc
     4741 ttacggccca agtcattgac cacacggtcg atcatcgcag atgaaaccag cgttttaccg
     4801 acagcaacat ctttgcccca ctgcggacga tgctggaaca ggtaattgat cgccaccgcc
     4861 aggtagtggt tcggattcat caaacctgcc ggagtgacga taccgtgacg gtcataatcc
     4921 gggtcgttag caaacgccag atcgaactta tcacgcagtg ccagcaggcc cgccatcgca
     4981 cactcggagg agcagtccat acggatcgcg ccgtctttat caaggtgcat aaagcggaag
     5041 gtttgatcga cctgatcgtt aacaatagtc aggttgaggt tgtaatactc gccaatacgc
     5101 ttccagtatt cgataccgga accgcccagc ggatcaacgc caagcgtcag gcccgctttc
     5161 tgaatcgccg ccatatcaac gatatcggcc agcccttcca caaacggctg caccagatcc
     5221 tgctctttca catgaccgga tgccatcgct tcgtcgaggg agatacgctt cacgcctttc
     5281 aggccatcag ccagcagtgc gtttgctctg tcttccacca ctttagtgac gttggtatca
     5341 gccgggccac catttggcgg attgtacttg ataccaccat cttccggcgg gttatgggac
     5401 ggtgtaatca cgataccgtc tgccagcggg ccaccttttt tattgtgaac cagaatggca
     5461 ttggaaatgg caggtgtcgg agtgaagcca ttgttttcct gcacaatgac atcaacgccg
     5521 ttcgctgcca gcacttccag tacggaaatg aacgcaggct cggacagggc gtgagtatct
     5581 ttacccacat agcaagggcc agtgatgccg tttttcgcac gttcttcagc aattgcctga
     5641 gcgatcgcca gaatgtgcgg ctcgttaaag ctgtggcgcg ctgcactgcc acggtgaccg
     5701 gaagtaccga atttcaccgc gtgctccgca ttccctgctt ctggtttcag tacataatat
     5761 tgcgccgtca gttgggcgac gttaatcaaa tcactctgtt gtgcaggttg gcctgcacga
     5821 ttgtggattg ccattgcttt gtcctttgtc tgcaacgttt tagatagttc cgcaaacctt
     5881 ctcaatcaat tccgccggga attgcatcga ctgcatgatg tgttcgatca tgctgcattt
     5941 acggccggtg ttggtgttgg tgatcaccca atacggcgta ccaggcacat gtttcggctt
     6001 ggtctgatta ccatttttca gcagcgtttg ttcatctgcc gcaaagtaaa cgcgtgtacg
     6061 accgtgcaac gattccgttg cttcggcaaa cgcctgggcg tcaagagaat atagtgtaga
     6121 caacagcagc ataaagcgat tgaccgctcg cttttgctct gcgtattcgt ccgaaagcag
     6181 aagttcacgc attgcgcgaa ccttgtcttt aatcgttttg accggcttcg cttcgacgat
     6241 agcaggtgac gcaacgcgaa cctctttcgt caccggagca gcaggctgtg atgcggcggt
     6301 aaatttcaac atacgccgta aaatgtcgga tgcgctctcg ccgatatgct tagtgtggct
     6361 ggcaatatag ctgtagagtt catcatcaac ttcaatcgtt ttcatcttaa tccagtgcag
     6421 tgtcttagct gaatacaagt cgccaggagt atatgaataa atcccggcag cggatagcgt
     6481 caagcctggc ttgcagaaaa actcggaata aaccttattt gttgcagccc tgtggcacaa
     6541 tggtcaacat aataccctaa cccgacaacg cgaaaaaaag aactttgcca tgaaattgaa
     6601 tatccgcgcg caaactgcac aaaaccagca caataattct cccatcgttc ttgtccatgg
     6661 tctgtttggc agcctcgaca accttggcgt actggctcgc gatctggtaa acgatcacaa
     6721 tatcatccag gttgatatgc gtaaccacgg tctttcaccg agagatccgg taatgaatta
     6781 cccggcgatg gcgcaggatc ttgttgatac cctggatgca cagcagatcg acaaagcaac
     6841 atttatcggt cactccatgg gcggtaaagc ggtaatggct cttactgcac tagcccctga
     6901 tcgcattgac aagctggtgg cgattgatat tgcgccggtc gattatcacg ttcgccgtca
     6961 tgatgagatt ttcgcggcca tcaacgcagt cagtgaatca gacgcacaaa cacgccagca
     7021 agcagcggca ataatgcgcc agcatcttaa tgaagaaggg gtgattcagt ttctgttgaa
     7081 atcttttgtt gacggggagt ggcgctttaa cgtgccagta ttgtgggatc agtatccgca
     7141 tattgtgggt tgggagaaaa tcccggcatg ggatcatcct accctgttta tccctggcgg
     7201 caattctccg tatgttagcg agcagtaccg tgatgattta ctggcacaat ttccacaggc
     7261 tcgggcgcat gtgattgcag gcgcgggtca ctgggtccat gctgaaaaac cggatgcggt
     7321 attacgcgct atccgtcgct atctcaatga ttaacgcaac tgattaaaaa cccagcgtcc
     7381 gcgtcgcttt ccgcgcgtgg acgttggcgt gactcatcgc gctgatgtat tatggcgcgc
     7441 tatccatccg ggcagaggcc tggctgattg tttcccccga agtcaccaag atcatggcca
     7501 aagaacaaac ggaccgtacg acattagatc tgttcgcgca cgagcgtcga ccgggacgac
     7561 cgaaaactaa tccgctttcg cgcgatgaac agctgcgtat taataaacgc aaccaactaa
     7621 aacgcgacaa agtacgtggc cttaagcgtg tcgaactgaa gctgaacgcg gaagctgtcg
     7681 aggcgctgaa cgagctggcg gaatcgcgta atatgagccg tagcgaactg atcgaagaga
     7741 tgttaatgca gcaactggcg gcgctgcgta gtcagggcat cgtttaaatt tccactttca
     7801 tgtagcacag tgtgcagtcc tgctcgtttg ctgattccgc aagactgcct gttctgctat
     7861 gattgccttt atccgtgggc aattttccac ccccatttca ataagtttca agaggttatt
     7921 tcactcatgg ctatcactgg catctttttc ggcagcgaca ccggtaatac cgaaaatatc
     7981 gcaaaaatga ttcaaaaaca gcttggtaaa gacgttgccg atgtccatga cattgcaaaa
     8041 agcagcaaag aagatctgga agcatatgac attctgctgc tgggcatccc aacctggtat
     8101 tacggcgaag cgcagtgtga ctgggatgac ttcttcccga ctctcgaaga gattgatttt
     8161 aatggtaaac tggttgcgct gtttggttgt ggcgaccagg aagattacgc agaatacttc
     8221 tgcgatgcat tgggcaccat ccgcgacatc attgaaccgc gcggcgcaac tatcgttggt
     8281 cactggccaa ccgcgggcta ccacttcgaa gcgtcaaaag gtctggctga tgatgaccac
     8341 tttgtcggtc tggctatcga cgaagatcgt cagccggaac tgaccgctga acgtgtagaa
     8401 aaatgggtta aacaaatttc tgaagagctg catctcgacg aaattctcaa tgcctgatgt
     8461 gatgcggcgt agactcatgt ctacgccgta ttaatagata atgccaatca aaataattgc
     8521 tacaaatttg taacttttgc tgttgtacct gtacaatgtc ccggtgttca agtggccttg
     8581 ccgttgtaaa tgtaagctgt gccacgtttt tattaacaat atttgccagg gacttgtagt
     8641 tttcatttag gcgtggcaat tctataatga tacgcattat ctcaagagca aattctgtca
     8701 cttcttctaa tgaagtgaac cgcttagtaa caggacagat tccgcatgac tgataacaat
     8761 accgccctaa agaaagctgg cctgaaagta acgcttcctc gtttaaaaat cctggaagtt
     8821 cttcaggagc cggacaacca tcacgtcagt gcggaagatt tatacaaacg tctgatcgat
     8881 atgggtgaag aaattggtct ggctacggta tatcgcgtac tgaaccagtt tgacgacgct
     8941 ggtatcgtca cccgccacaa ttttgaaggc ggtaaatccg tatttgaact gacacagcaa
     9001 catcaccacg atcacctgat ctgcctcgac tgcggtaagg ttatcgaatt tagtgatgat
     9061 tccatcgaag cgcgtcagcg tgaaatcgcc gcaaaacatg gcattcgcct gactaaccac
     9121 agtctctatc tttacggtca ctgtgccgaa ggcgattgcc gcgaagatga gcacgcgcac
     9181 gaaggcaaat aagccagcct gaacgagaaa agccaacctg caggttggct tttttataca
     9241 agggaaataa gaaaagcgag agttacagct ctcacttatt tgttattact gcgaatttcc
     9301 tgccagacct tatcacaatc ggctttcacc gcctgatcat ttccggtttg cgttgcctga
     9361 atgcactgct gataatccag tacgcggaca ctttcctgct cggcaaactg ctgatgttgt
     9421 ttctctttct tcagcacgtt taacacgctc tggcaggctt caattttttc cggcgaacct
     9481 tgcgcggtgt tgatacaggc gctgtaagcc tctttcagac gactgtcttc ctgtggcgcg
     9541 gttgattgcg cacaagccac cagccccgat gccatcatgg cgatgagaat cagttttttc
     9601 atagcaaatt cctcaaacgt gcggcaggca caaaacctgc cgcatcgggc atcagaagat
     9661 ggtgaatggt gcgattacca taaatttcac gtcacgctca tcctggaaga tgttgccata
     9721 accaccgccc cagcttggga tgtcggagtg gttgtcgtat tcggtgaagt gcagtttgaa
     9781 catcgtgcct ttggcgcggc cgtcctgaat ggtgtagacc gcatccaggc tgtaggcaga
     9841 ctcttcaata gtccggtttt tgtcgtagta cgcatccgga ttgctctgcc aggtagcggg
     9901 tttagcatcc catgcgtaaa cgtaggaggc gccgatggca aaacctggaa gattccagtt
     9961 tttcaggtca tacatcgcgc cgaagaagac cgctttttcg ccgttggcgt tgaagtcaga
    10021 acggttatcc caccagatat ccaggcgacc gttcgaggaa gcgtaggttg gtgtcatacg
    10081 ttgcaggaag tatccctgct gaccgtcggc tttaacccag gtgccttcca gacgcaaatc
    10141 cactacgtca gccgcccggt aaccaaaggt caacgcctgc agccaggcgg tgccgtcata
    10201 aagatcgttg gcgctgcgat cgtcaacttt atcgcgcgtg ccatagaact ggtagctggt
    10261 ggttaacggg ctaccggcga tatcaaattt gtagctggct ttggcaaaat attgatcgat
    10321 atacccttcg gcctgaccaa acgccgcttc cagtacgaag ttatttttga agtcgtactt
    10381 cgccccaagg gagtgtagat aatcaacttt ggtggtttta tcgttctgat aaaactcatc
    10441 catttccaga tgccacggtg ctttgtattc gttggtccac atgtaggaga aactcaacgc
    10501 accagcatcg ccgtaatcaa aattcgcccc ggcctccgcc ccctgataag tacccggcat
    10561 aaagctccag tgtggcgcta acagcgtctg accggttggc tgaatataac ctgccctcgc
    10621 ccaaaccgga ccgtatttaa atttggccgc tgctttatac aggcttatac cgcttttatc
    10681 gccggaccag tcttcgtcat aggctttatt actttttgaa aacgcgattt cgttcgggtg
    10741 agagctgtcg ccgttttccg ccatttcaat cgccgtaaac gcggcaatat caaggccgaa
    10801 catatcagca gcataaccag actgaaaatc gaggttggcg ttccaggtgg agtgagaaag
    10861 gttggttttg tatttatcgc cgtcggtaac atctttacgg tcgcgttcac gctgccagta
    10921 atagataccg ccggttaagg ttgaatcgtc gatgaatcct tcggcgcgag cctccggaat
    10981 tgccataaag cccgacatag ctgtaacacc ggcgatagcc agcgccagcg tactacgttt
    11041 gccactaaac gcacgcatgg gttaatcctc tttgacgtat aaattgctgc accaaaggtg
    11101 aacagcgaaa aaaataaaaa ttaaaaaagt agcgttgaga aaagtctcgc t
//
LOCUS       DAFGPF010000144        11099 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFGPF010000144 DAFGPF010000000
VERSION     DAFGPF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11099
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.144"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..691)
                     /gene="iucD"
                     /locus_tag="LSX49_004461"
     CDS             complement(<1..691)
                     /gene="iucD"
                     /locus_tag="LSX49_004461"
                     /EC_number="1.14.13.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent L-lysine N(6)-monooxygenase"
                     /protein_id="HBL7170774.1"
                     /translation="MKKSVDFIGVGTGPFNLSIAALSHQIEELDCLFFDEHPHFSWHP
                     GMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKHKKFYRFLTSRLRTVSREEFSDY
                     LRWAAEDMNNLYFSHTVENIDFDKKRRLFLVQTSQGEYFARNICLGTGKQPYLPPCVK
                     HMTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRN
                     NFNALDEAAFAD"
     gene            complement(688..2430)
                     /gene="iucC"
                     /locus_tag="LSX49_004462"
     CDS             complement(688..2430)
                     /gene="iucC"
                     /locus_tag="LSX49_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucC"
                     /protein_id="HBL7170775.1"
                     /translation="MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGA
                     QWRFIAERGIWGWLWIDAQTLRCTDEPVLAQTLLMQLKPVLSMSDATVAEHMQDLYAT
                     LLGDLQLLKARRGLSASDLINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
                     TNTFRLHWLAVKREHMIWRCDNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPL
                     PVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPL
                     TIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYA
                     ALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLD
                     AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLV
                     KEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQ
                     LLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLED
                     LQNPLWLVTQEYES"
     gene            complement(2430..3377)
                     /gene="iucB"
                     /locus_tag="LSX49_004463"
     CDS             complement(2430..3377)
                     /gene="iucB"
                     /locus_tag="LSX49_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(6)-hydroxylysine O-acetyltransferase"
                     /protein_id="HBL7170776.1"
                     /translation="MSEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGW
                     LCDALDQIFIAAPQLSAVALPWAEWREEPQALTLFGQVKSDIIHRTAFWQLPLWLSSP
                     ANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
                     MNDPRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIG
                     RHYSWQPFDRGLHLLVGEQQWRGAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNLR
                     LFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL"
     gene            complement(3378..5102)
                     /gene="iucA"
                     /locus_tag="LSX49_004464"
     CDS             complement(3378..5102)
                     /gene="iucA"
                     /locus_tag="LSX49_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucA"
                     /protein_id="HBL7170777.1"
                     /translation="MTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDE
                     QKSLHFRVAYFSPTQHHRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLC
                     ETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFN
                     RREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDN
                     QWLFPLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIK
                     FSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTFRVMQEDGWAGLRDL
                     NGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITV
                     QQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSA
                     FMPHATDWLDSIGEAQAENIFTHEQLLRYFPYYLLVNSTFAVTAALGAAGLDSESNLM
                     ARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFA
                     NPLQAQEV"
     gene            5238..6431
                     /locus_tag="LSX49_004465"
     CDS             5238..6431
                     /locus_tag="LSX49_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170778.1"
                     /translation="MSPGIEDTPQKPLSCWPLAFSAGLLGIGQNGLLVVLPVLVIQTN
                     LSLSVWAALLMLGSMLFLPSSPCWGKQISRTGSKPVVLWALGGYGISFTLLGLGSVLM
                     ATSAITTAVGLGILIIARIAYGLTVSAMVPACQVWALQRAGEGNRMAALATISSGLSC
                     GRLFGPLCAAAMLAIHPLAPLGLLMAAPVLALLMLLRLPGTPPQPTPECKSVSLKRDC
                     LPYLLCAILLAAAVSMMQLGLSPALTRQFATDTTAISQQVAWLLGLSAVAALIAQFGV
                     LRPQRLTPVALLLSAGVLMSGGLAIMLSEQLWLFYPGCAVLSFGAALATPAYQLLLND
                     KLADGAGAGWLATSHTLGYGLCALLVPLVSKTGVAIALIMAALFATILFTIVSVFIWH
                     YRTIK"
     gene            6793..7006
                     /locus_tag="LSX49_004466"
                     /pseudo
     CDS             6793..7006
                     /locus_tag="LSX49_004466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(7149..7577)
                     /locus_tag="LSX49_004467"
     CDS             complement(7149..7577)
                     /locus_tag="LSX49_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF417 family protein"
                     /protein_id="HBL7170779.1"
                     /translation="MKKFINVYIKSDYDIVILRLSVIIIFMLFGTYKWFDFEVMALKP
                     LISPTWLNILYIMFGVHGGSYFLGIVETITFLALSIGFFRPAAGILGDIIVIVTGLVT
                     LSLLPQLGKVDSFVIKDVLLLGAGSVLLKYDLKNYLNIKN"
     gene            complement(7617..8177)
                     /locus_tag="LSX49_004468"
     CDS             complement(7617..8177)
                     /locus_tag="LSX49_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000109148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7170780.1"
                     /translation="MSTYENILRITDTLIQQRGFLGFSYADLEKEIGIRKASIHHHFP
                     RKTDLGIAYCQYKTEVFDRLNITLHNVSSGVQRLRTYLDAFAGCAERGEMCGIYAMLS
                     DSHQFSPELQEAVSQLAHQEIQMIKDIITSGQNSGEFKTVLLPDELAVIVCSTLKGAL
                     MLNRLPPHDIYSGTVNALIKMLDTRT"
     gene            complement(8219..8479)
                     /locus_tag="LSX49_004469"
     CDS             complement(8219..8479)
                     /locus_tag="LSX49_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBL7170781.1"
                     /translation="MNYVICTTIVALGLILTGYATAADEINRQDVVGLMPSDYISVGN
                     LYTPEEVATALKDKAEQAGGSHFRITSLGGKNKLDGTAIIYR"
     gene            9028..9777
                     /locus_tag="LSX49_004470"
                     /pseudo
     CDS             9028..9777
                     /locus_tag="LSX49_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343760.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            10313..10426
                     /locus_tag="LSX49_004471"
     CDS             10313..10426
                     /locus_tag="LSX49_004471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HBL7170782.1"
                     /translation="MKMKHLRDDVAAGRRRLYIRAICPSLREAPLLYSYPL"
     gene            10517..11099
                     /locus_tag="LSX49_004472"
                     /pseudo
     CDS             10517..11099
                     /locus_tag="LSX49_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     misc_feature    10798..10914
                     /locus_tag="LSX49_004472"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /pseudo
                     /db_xref="RFAM:RF01497"
BASE COUNT         2840 a         2718 c         2837 g         2704 t
ORIGIN      
        1 catcagcaaa agcagcctca tccagtgcgt taaaattatt acgccgggag acccagttta
       61 tttccgccgc ttctccccat tccccgcgta atgcattaag gaacaggtct gcaccactct
      121 gtcctccacc aaccacggtt atccgttttc cactaaggtc cggccgacga agattcattt
      181 cactggcatg gaaacaggat tgtgtcatat gcttcacaca gggtggtaaa taaggttgtt
      241 ttcctgtacc aaggcagata ttgcgggcaa aatattctcc ctggctggtt tgcaccagaa
      301 acaatcgacg ttttttatcg aaatcaatgt tttcaacggt atgactgaaa tacaggttat
      361 tcatatcttc agcagcccag cggaggtagt cagaaaactc ttcacgggat actgtacgta
      421 gtctgcttgt aaggaagcga tagaactttt tgtgcttcac cagatagtta acaaaactgt
      481 agggatttgt aggtgcaaca gcactgacca gatctttcag aaagacggtc tgcatatgac
      541 aatccggtac cagcataccc ggatgccagg aaaaatgagg atgttcatca aagaagagac
      601 agtccagttc ttcgatctga tgtgacaacg cagcaatgct gagattaaat ggccctgtcc
      661 ctacaccaat aaaatcgaca ctttttttca tgattcatat tcctgagtta ccagccacag
      721 cggattttgc agatcctcaa ggtaattcgg cagcatgcgg ctgccgccat ccagatcagg
      781 ccaggtcagt tttaccgggt tcagcaccac gcgaatgatt tgtggcctga aaagtgagaa
      841 aagcgcaaaa cgctctgaca tttgtggatg ttttttcatg taatcactca acactgctgc
      901 cagcagttga taaaatcgcc tttcaggtac gccaagacga accatcagtg gcgaaataaa
      961 acgcagtact gtcacgaagt gacccgtctg caaatcatgg attaagtagt ccgcactcag
     1021 gcgggatgta acatcacgaa cctcctgagg caaagagtcc atttcgggga actcttcttt
     1081 caccagtcgc atatcgccct ggaagtcttt cagcagaaca cgctgtggaa ccccctcttt
     1141 catggcgaga gttatatttt gtccatgtgc aataagcgcg acaccgtagc ggcaaagcag
     1201 gtgatacaga ggaaccacga ccacccggaa cagttgcgta agccaggttt cagcgtccag
     1261 cccggagcgg tctatatatg cgcctgccag cggctgattg ttttcgtcgc actccatcag
     1321 tgttgccatc agaaccggac tttcatccgg tttcagccag cggcacggat tctcccgcca
     1381 gataacacca agcatttcct ggtagcgata gggagcccgg gcaagcgcgg catagccttc
     1441 atgggagaca tagcctgcag ccggttcacc aagtatcact gcgccgcttt gcaccagggt
     1501 ggcgtcggtc gcaaaaacct gttgtagcca gcgtgaagcc agtggtccgg cagcgatgta
     1561 tctgccaggg atcccccggt agcatgaggt gttgtagatg gtcagcggca gcttgatatc
     1621 cagcccgccc cggcgactgg cgttggtcag ggtacgcagc gactgctggg cgagccactg
     1681 gtcgccaaac tcgccgagag acaccatcct gccttcggca aaatcagcga tgaagtcggt
     1741 agcgattttt tgctgccact gccacggatg taccggcagc ggcagccagt tgtgatccag
     1801 tccgttttcc tgccagacct gactgaagcg tgtaaactcc tgcggatcca ttgcggcagt
     1861 caacaactgc tgaatatcca gatcgttatc gcagcgccag atcatatgtt cacgttttac
     1921 cgccagccag tgcagtctga aggtgttggt atactctggc gcatatcgtt ccagcgcctc
     1981 tttgccccag ccacggcgac ctttattaaa aacgaattta ggatgaccgc tcagcaggca
     2041 ttgcagacga tcggcatcaa gattaatcag gtcactggca ctcagtccgc gacgggcctt
     2101 cagcagttgc aggtcgccca gtagcgtggc atacaaatcc tgcatatgct ctgcaacagt
     2161 ggcatcactc attgacagca ccggctttag ctgcatcagc agcgtctgcg ccagtactgg
     2221 ttcgtccgtg cagcgcaacg tttgggcatc aatccacagc cagccccaga taccacgttc
     2281 agcgatgaag cgccattgtg ctcccggcag gttaatgcag tagtggtcat cgccctgaga
     2341 ttccgcgtgg aaaacctgct catactccat ctcagacaac atttttgcca ccagccgacg
     2401 gttaacaaaa tcccagtcct tgtgattcat tacagaccga cctccgtgaa gaagtgatga
     2461 cgatccgcca tcaccatgcg cgagcgctta tgtgggaagt cgaactcttt aattgtccgg
     2521 tatcccgcag gctcaagatg gcggaacagg cgcaggttat cggtgcgtgg ctccagtact
     2581 gtgcgctgcg tacggggctc atccagcagc aggtaatgtg tcagcccgcg cagccagctt
     2641 tgcacatagt gggccccgcg ccattgctgt tcaccaacca gcagatgcag gccacggtca
     2701 aagggctgcc acgaatagtg acgaccaatg cggtcttccg ccgcccagta gatttcgaaa
     2761 tagctgaatg gccgatcgtc gaagcaccca atcagcggga atgcatgttt accggtgagc
     2821 tggcgctcca gataggcggt ctgtacctcc agtgagccac tttgctccca gaaatactca
     2881 acgcgcggat cattcatcca gcgggtgaaa cgttctgcat cagaaacggg atcggcaatg
     2941 cggaaactca gcatcctgcg aatacgtgga tcgtaacggc ggtaaacctc accctgtgga
     3001 cggggtgggc gctgcgggaa ataaatctca cgctctgcat caaaaaccat ttcaccggag
     3061 gcccggtttg ccggtgaact caaccataac ggtaactgcc agaaggcagt acgatggata
     3121 atgtcgcttt ttacctgccc aaaaagcgtc agcgcctgtg gctcctcacg ccattcggcc
     3181 caggggagag ccactgctga cagttgtgga gcggcgataa atatctgatc cagcgcatcg
     3241 cacagccacc ctgtcggcag ctccccggga cagtgcaaca ccgcgctatt gtccagtccc
     3301 cagccaagat tcaggggctt gtcgagtttt tcacagcgca gtccatatct gctgtgaata
     3361 atgtttgcct cagacattca gacctcctga gcctgcagcg ggttagcgaa atcgaaatag
     3421 atcaccgaag ggtcaacaat ggtgttctcg ttatgatcgt tcagataaca gaaaaagtta
     3481 ccttttacgt tccagtacgg actttccagc acgtagttga gacaggtttt atgagtcacc
     3541 tgatcacgca cttcagccag cgatgctcgt acacgagcca tcagattcga ttcgctgtcc
     3601 agcccggcag cccccagcgc agcggtcaca gcaaaagtgg agttaaccag caggtaataa
     3661 gggaaatagc gcagcaactg ctcatgggtg aaaatatttt ccgcctgcgc ctcgccaata
     3721 gaatcgagcc agtctgtcgc gtgaggcata aaagcgctgc cctgacagtc acggtaaata
     3781 aatccgaccg gcagatcccc aagcatctgg acaagaatat tttgctgatg cgccagcagc
     3841 accaggccgt aatccgcttc agccgtaaac agcggcttta gcacttgctg acagtatgca
     3901 tcgacccatg catgggcggc ctgttgcaca gtgataccga ggcgatcgct caggcgtttt
     3961 accgccgaaa ccagcagcga atcaccgcca tcaggtgcgg cctgagtcag ggagaccagt
     4021 acgttagtct ggcttttcgg ctgatccacc agcagatttt cacgcagggc aaacagactt
     4081 tcctgcatga tgttgccgtt aagatcgcgc agcccggccc agccatcctc ctgcattacc
     4141 cggaaagtcg ggaagcggac ctgtagcatc tgccagccgt cggtttgagc caggcgtgcc
     4201 aggcgcatcc cacgcttcac ttctttcacg gacagagtac ggatggagtt ggtcagccgt
     4261 acgctcaggg agaacttgat catatcgcgg ctggtggcac agtagaggga acgggaagag
     4321 gtggtcggca gccacgacgt gccggcctca cctaagtctt taatcagccc tttagcaaca
     4381 agtgcctggc accacccctg ctgcaaaaga tattccccct gccacgggtg caacgggaac
     4441 agccattggt tgtcacttaa ttcgttgagt aactgaggcg cattctctgc ggcaaatcgc
     4501 gtcagccgct gttgaaggtt gagatgcaaa ctttcaccgg cgatttgcgt tttatccacc
     4561 gaaaaccacc gcagtgggaa gtggggtgcc atatcaggca ggtagcgttc agcctcccgc
     4621 cggttaaacg gttcatgaga cttaggcgca gggtggaaag cgtgtcctgt cagcagcgcc
     4681 tgctcagcct cgccaaaatt caacgctttt tcacgcagag cggcccagtc atgacgggca
     4741 tcaattgcct gttgcgtatg gacatggctt tccagcacgc gctggtggaa agtttcgcag
     4801 aggggaacgg gcagaaacag ttgatggcgt agcttatcaa taataagccg ggagagagtg
     4861 gtaaagtcga caggataact gcctgatgcc gtgaccagac gtgcaggaaa tgcaaagcgg
     4921 tgatgctggg ttggggagaa ataagccact ctgaaatgga gcgatttctg ctcatccagc
     4981 gggatgagca attcgtctgg cgggtattct gtcagtttcc agtctgtggt ttcacgaatc
     5041 agtgcattca ggaagcactg cgcagccaca tctgtggctg gtttttcaga gggcagggtc
     5101 atagtcaaac agctcccaca cagcaaaata ataacaatta tgtcaataat gattctcatt
     5161 atcaataata aatgttattg tcagataaat taattttaca aataaacaca attaatacat
     5221 ggagttgaaa cattataatg tcaccaggga tcgaagatac gccccaaaaa ccactgtcct
     5281 gctggccact tgcgttcagt gccgggcttc tcggtatcgg acagaacggt ctgctggttg
     5341 tgctccctgt tctggtcata cagacaaatc tgagtctgtc tgtatgggct gccctgctga
     5401 tgcttggctc aatgctgttt ctgccatcgt ccccgtgctg gggaaagcaa atttcccgta
     5461 ctggcagtaa acctgtggtg ttgtgggctc tgggaggata tggcataagc tttaccctgc
     5521 tagggctggg aagcgtgctg atggctacca gcgccataac aacagcggtg ggactgggaa
     5581 tattaatcat cgcccggatc gcctacgggc tgaccgtgtc ggcaatggtg ccagcctgtc
     5641 aggtctgggc attgcagaga gctggagaag ggaatcgcat ggccgctctg gcaaccatca
     5701 gctccggcct gagttgcggc aggctattcg ggccgctgtg cgcggcagca atgctggcca
     5761 ttcatcctct ggcgccactg gggctgctga tggcagcccc agtgctggcg ctgctgatgc
     5821 tgctgcggtt gcccggcaca ccaccacagc ccacaccgga gtgcaagagc gtcagtctga
     5881 agcgggattg tctgccttat ctgctttgcg caatattact ggctgcggcg gtgagcatga
     5941 tgcagcttgg actttcgcct gcccttactc gccagttcgc cacggatacc accgccatta
     6001 gccaacaggt ggcctggctg ttgggtctgt ccgcagtagc tgcgcttatc gcgcagttcg
     6061 gggtactccg tccgcagcgc ctgactccgg tggccctgct cctgagtgcc ggagtgttga
     6121 tgagtggtgg tctggctatc atgctctccg aacagctatg gttgttttac ccgggctgtg
     6181 cagtgctgtc atttggagca gctctggcaa cacccgctta tcaacttcta ctgaatgata
     6241 agctggctga tggcgcaggc gcgggctggc tcgctaccag tcacacactt ggctatggac
     6301 tgtgcgcttt gctggtgccg ctggtatcga aaacaggtgt cgcaatcgcg ctgattatgg
     6361 cagcattatt tgcaactata ttatttacca ttgtgtctgt atttatctgg cattaccgta
     6421 ctatcaaata aagatatgat catcacctta ctggagtaaa tcagaggata tgagagagga
     6481 cctgcgtctg atgaaaacat gtcaggcagt gttctggctt gctgcccccg cctggtttac
     6541 gttacgccct tagctacctg gctaaacagg atcagaaaga acacggtatt attctgatgc
     6601 gtagcagact tcccgaaaaa agtaaccgcg gccgaccacg acacaactga attacagctg
     6661 tattagaatt aagtttccgt aagttgttgg gaggtgcttg agttaatagg cagcagaggg
     6721 ggcgctgtaa tcagtgtagg ggacccgaat ttctgctgtg gtgcttcagt ggttcggata
     6781 caggtaacga atatggttca taaatctgac agtgatgaat tagcagcact gagggaagac
     6841 atcacttgaa gcttatggga ttgaatggcg acgtaaaccg cagagtcctg tgcagtgcgt
     6901 ttccgtatta tccacggatg agaaagttgc gttatttcgt cggttgtttc gtgggcgtag
     6961 tgatgtatgg ggccttcgat gggaaagtaa aactagcgga aaataaaagt actcgcctgc
     7021 ctacggacct ttttactcag ggtatttttg ttttccataa cgttgcgtat taacatgaag
     7081 gagaacgagg gggattaggt aatctctttc catgaaaata cgcaaacgtt catcaccgaa
     7141 gtgaaaaatc agtttttgat atttaaataa tttttcaaat catatttcag caggacacta
     7201 ccagcaccta acagcagcac atctttgatg acaaaactgt caacttttcc cagttgtggt
     7261 aacagactta gtgtgactaa acctgtaaca ataacgataa tatctcccag tatgccagca
     7321 gcaggcctga agaagccgat actcagtgct agaaaagtga tagtttctac tatgccgagg
     7381 aaatagctcc ccccatgaac accaaacata atgtacagga tattcagcca cgtgggagaa
     7441 atcaggggct tgagggccat cacttcaaaa tcaaaccatt tataggtccc gaagagcata
     7501 aatattataa taacagacag gcgaagaata actatgtcat aatctgattt aatgtaaaca
     7561 ttaataaatt ttttcatttc attctccggg tggaaaatta tatgcactaa aaaggattaa
     7621 gtacgggtat caagcatttt aattaaagcg ttaacggttc ctgaatagat atcatgtggt
     7681 ggaagtcgat ttaacatcag tgcccccttt agtgtagaac agactataac ggcgagctca
     7741 tccggaagaa gaactgtttt gaactctcca ctattctgcc cggaggtgat aatatcttta
     7801 atcatctgta tctcctgatg tgccagttga cttacagcct cctgtaattc aggagaaaac
     7861 tgatggctgt cggatagcat ggcataaata ccgcacattt cccctctttc agcacaacca
     7921 gcaaatgcat caagatatgt cctgagacgt tgtacacctg aagaaacatt atggagagtt
     7981 atattaagtc tatcaaatac ttctgttttg tattggcagt aggctatacc aagatcagtt
     8041 ttcctcggga aatggtgatg aatactggct tttctgatac caatttcttt ttccagatct
     8101 gcgtaactga accccaaaaa tccgcgttgc tggatcagag tatccgttat gcgaagtata
     8161 ttctcataag tagacacggc tttacctgtt atgtattaaa gggactatta tacatatttt
     8221 agcgatagat aatggcagtt ccatcaagtt tattttttcc tcccaatgaa gtgattcgga
     8281 aatgagaacc tcctgcctgc tccgctttgt ctttaagcgc agttgccacc tcttctggtg
     8341 tatatagatt accaacagaa atatagtctg acggcatcaa accaacaacg tcctgacgat
     8401 taatttcatc tgcagcagtt gcgtagcctg tcagaatgag accaagggcg acaatggtag
     8461 tgcagataac ataattcatg agcaatttct ctttatgttt gcgatactac acatgctacc
     8521 ttctgattgg taggcttgca agatggattt atttaaaata agagggatga tttgtatcaa
     8581 attgttttgt atttttgtgt tttgtatcac tgaggtgaag ttgtaagatc tggccctctg
     8641 cgaggttggc tctgtcgaaa ggaacaggtg acgagagtta acatcgttgc cttggctgca
     8701 tgggggatat gtagctaccc cctgatattt ccgccacgga agccaatatg aacaacaata
     8761 acaatacgcc tcgtttccag tatgcttcat gtcggatatt ttgtaagcgc tatgtacttc
     8821 ccgggacgct tatcttttag ccgtagctgg tagtgcaata aaagcctggc agcaatccag
     8881 gcctctacgt tctaagaatc aactgtcagt gcagaggaat gcgcacgacg ctctcgttgt
     8941 tattggcttt tgccgtcgca ccgtcgtttt tcacggtgac aaacagcgcg tgcgctttgc
     9001 tatccgtctt atatcactgg tgctgacaat gtggatgagg tcgcctttaa aaaaggacat
     9061 cgttatataa cggtgatctc cgatcgcgat ggtcgtgcgc tggccttaac ggacgatcgt
     9121 ggcacagaga gcctcgccgg ctatcttcgc acgcttactg acgggcagtt gctggctatc
     9181 aaaacgctct caatggacat gaatgcaggc tatataagag cagcgcgtat ccacttaccc
     9241 tgtgcggttg agaaaatcgc cttcgaccgc ttccatgtag caaagcaact tggcgaagtg
     9301 gttgataaaa cccgtcagaa tgaacatccg cacctccctg ttgaaagttg gcgtcaggca
     9361 aaggggaccc gcttcctgtg gcagtacagc gataaatgga tgaccaaatc caggcaggaa
     9421 aagctgatat ggctgcgtgc acagatgaag ctgacaagcc agtgctgggc gctgaaagag
     9481 ctggcaaagg atatctggaa caggccatgg agtgaggaaa gacgtaatga ctgggagaga
     9541 tggctggctc tggcggccaa cagtgacgtt cctatgatga aaaacgccgc gaaaacgata
     9601 ggaaaaaggc tttacgggat cctgaatgcc atgcgacacc gtgtctcaaa cggaaacgcg
     9661 gaggcgctta acagtaagat caggctactg aggataaaag ccaggggata ccgaaatcgg
     9721 gagcgcttta agctgggcgt gatgttccac tacgggaaac tgaatatggc gttctgagcc
     9781 ttcccaccat gatcagggaa aacccatgta tcatcaggtt attatgtgag ctggtaaatc
     9841 agattttgca tggactgaaa tcatgctgtt atttagggat aaagaaccgg ctttttgtcc
     9901 cgccccctcg ccattaatga aaaaaagaat ggaatgctcc ctctgaggag aagggcagta
     9961 gaaaaaagaa cccgccagca aaaatattgg ggatgaacag ctttcgctac tcagattgct
    10021 ggcgggtata gttcctcatg aaataaaaat actacataat ccttttaatg caaatgataa
    10081 tcattgtcaa ttgtttgtgc gtgttttctt catacatgat tggtagtaaa ggtgattcag
    10141 gctatcagtt tttgctgatg atctttttat ctatagaaaa catcagccaa gctggttggt
    10201 tcagtaacgc tttcatcttt gagcatttta taaaaaattc ttgaattgtt aaaatagatt
    10261 aaagtctggt aacagcaaaa gttaaacgag aaatcaaaag gaggtcccaa atctgaaaat
    10321 gaagcatctg cgtgatgatg ttgcagcggg acgtcgtcgg ctgtatatca gagcaatctg
    10381 tccatccctg cgtgaagccc cgttacttta ttcgtacccc ttataatggg gtgttagcca
    10441 gccagacccg gcatgattac tgtgaaccgc cccgggaatc ctggagacta aattccctga
    10501 gaaagaggta aacaggatga ctaaaaatac acgtttttcc cccgaagtcc gtcaacgggc
    10561 agttcgtatg gttctggaaa gtcaggacga atatgactca caatgggcgg caatttgttc
    10621 catagctcca aagattggct gtacgccaga gactctgcgt gtctgggttc gccagcatga
    10681 gcgggatacc gggggcggtg atggtgggct caccaccgct gaacgtcagc gtctgaaaga
    10741 gctggaacgt gaaaatcgtg aactgcgccg cagtaacgat atccttcgcc aggcttccgc
    10801 ttattttgcg aaggcggagt tcgaccgcct ctggaaaaaa taatgccact gctggataag
    10861 ctgcgtgagc agtacggggt cggaccggta tgcagtgaac agcatattgc cccgtcaacg
    10921 tattaccatt gtcagcagca gcggcatcat cctgataaac gcagtgcccg ttgtcagcgc
    10981 gatgactggc tgaagagaga gatacagcgc gtatacgatg aaaatcatca ggtgtacggt
    11041 gtgcgtaaag tctggcgtca gttgttacgg gaaggaatca gggtggccag atgtacagt
//
LOCUS       DAFGPF010000145        11068 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFGPF010000145 DAFGPF010000000
VERSION     DAFGPF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11068
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.145"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1349)
                     /locus_tag="LSX49_004473"
     CDS             complement(<1..1349)
                     /locus_tag="LSX49_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HBL7170783.1"
                     /translation="MTSKNFALITAMTQAELTQKVNEHLAKGWHLQGETRVAYEPGTP
                     WYLMQAMVADGTTDISPDSPQHGSVPEWYYVVVLAGQSNAMSYGEGMPLPDSYDAPHP
                     RIKQLARRNTVTPGGKACAFNDIIPADHCLHDVQDMSALNHPNADLSKGQYGCVGQGL
                     HIAKRLLPYIPQNAGILLVPCCRGGSAFTQGAEGTFSESTGASQDSARWGVGKPLYQD
                     LILRTKAALQKNPKNMLLAVCWMQGEFDMSAATYSQQPPLFTAMLKQFRADITEFNTQ
                     CHGGRAASVPWICGDTTYYWKNTYGTQYDTIYGAYKNRESDNVFFVPFLTDGSGNNTS
                     TNAPTEDPDAASEGYYGSASRTNKNWVSSNRQTHFSSWARRGIIPDRMATAILNVAGR
                     TLAFISGKAPEIKPSPGGDTPSGPSEDASVRTISLLPTAGDAAAQGWSIKNGGIQLS"
     gene            complement(1488..1883)
                     /locus_tag="LSX49_004474"
     CDS             complement(1488..1883)
                     /locus_tag="LSX49_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2570 domain-containing protein"
                     /protein_id="HBL7170784.1"
                     /translation="MKLWPTLGVAFLLITSMRLSWSLGRENARNEAQASTLKSTVDTL
                     NIISAGVQDMQQVLAQLRAENQQRNQDGEVRREQLRNDIAKDECAHALPDARFTDRLR
                     RHAERARASAVSPAYTADADHAGNASPLP"
     gene            complement(1880..2272)
                     /locus_tag="LSX49_004475"
     CDS             complement(1880..2272)
                     /locus_tag="LSX49_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBL7170785.1"
                     /translation="MSNTFKFSSRSEKNLQGVNPDLVKVTRRALEISEVDFGITEGLR
                     SRYRQKQLVTTGKSQTMNSRHLTGHAVDVVAYVGNQVSWEWPLYEKIAAAFRQASQEL
                     NIPVEWGGDWKTLKDGPHFQLPHGAYPA"
     gene            complement(2269..2592)
                     /locus_tag="LSX49_004476"
     CDS             complement(2269..2592)
                     /locus_tag="LSX49_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL7170786.1"
                     /translation="MSTIQTGITEQVIAWLFDHLPTVYAVGAAVSISALMSLYDGRTL
                     VQTVTGSLACGVLAMAVAGSLRFFGIPEDAVTFFGASIGFMGAEKARDKVIAIFDRRV
                     KERNE"
     gene            complement(2595..2795)
                     /locus_tag="LSX49_004477"
     CDS             complement(2595..2795)
                     /locus_tag="LSX49_004477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HBL7170787.1"
                     /translation="MKVKALEGDTVDSLCFRYYGTTQGVTEKVLDANPGLCQQVFLDA
                     GQEVEMPEPEKKKREMIQLWGE"
     gene            complement(2795..3289)
                     /locus_tag="LSX49_004478"
     CDS             complement(2795..3289)
                     /locus_tag="LSX49_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HBL7170788.1"
                     /translation="MSMVARTNPGPAEDDITDTDDGDTRISAGAFWPDIVLRELRLAV
                     RLPGRVTTSRLLHTATGAIAHVTRELEAWQQEQQAAGYQTLADVPAPVINGESVNLWH
                     WRNAVYTATRALILERYRDADTTDKGDRRADALDIQTSDLWRDVSWAISDILGRPRMF
                     AELC"
     gene            complement(3391..4191)
                     /locus_tag="LSX49_004479"
     CDS             complement(3391..4191)
                     /locus_tag="LSX49_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBL7170789.1"
                     /translation="MITPAQQHWQNVMAQRAGRANEGVDHAACTAHEEVLYRLRLAQA
                     RLKAIQARSAKAAIKKELLPDFSGWIEGTLEADGGQQDEVIATLMVWAIDCGDLPLAL
                     RIGAYVVRHNLIMPDNFGRTAATVLTEEICNPVLTQAGTDADADLSAFIEPLDTLWEI
                     IANQDMPDEVRAKLCKACAFARRGLTDADNMASSLKLLREAMHLNPNAGVKREIATLS
                     RALKKADSAAEPEDASAQQAQDESSKSKKTTRKPATRKTTATQKAKRG"
     gene            complement(4237..5289)
                     /locus_tag="LSX49_004480"
     CDS             complement(4237..5289)
                     /locus_tag="LSX49_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HBL7170790.1"
                     /translation="MNLVMSDITRNKLGCYMAQQASLNNIPVSALVSRFTVEPAVQQR
                     FENASKESTEFTKRINVIGVTDQKGEKILLDTTGPIARTNSSYDGIKRRNPNNVIDMK
                     SRQYQCEQVNYDTFISYPQLDTWAAHSDFQSRISTQIARQVALDRIMIGFNGTSHAYE
                     SDFHTNKLLQDVNVGWLEHIRTDASERVMNDVTLTSRNMDNTVAHAGKYANADALVQD
                     ARSSLLDEWHKEADDLAVIMGRNLFNSLRLPVLNSISGQNPNAELLAGQLILSSRTIG
                     GLGVFLAPFFPDATMLITSFNNLSIYWQKGSMRRLMKDEPEYNRIATYQSINDAYVVE
                     DYGKCAMVTGLKFADS"
     gene            complement(5313..6149)
                     /locus_tag="LSX49_004481"
     CDS             complement(5313..6149)
                     /locus_tag="LSX49_004481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HBL7170791.1"
                     /translation="MANEKKTSRKKFRVAVSGSTVDGREISPVHLREAAENFNPDVYA
                     ARVNVEHYLSPCPSSEFSAMGDVTALSTEDITEGPLAGRTALYAEIEPTERMKQLVAD
                     GKKIYSSIELHPQFSVNGRAYLVGLAMTDTPASLGTERLKFTAQQRQAVMTFNSIQGE
                     APLISEAIESEIIEMAEQRQEEGTQWFNRVMGIIGRGRKADDASFSRIQEAVEGVATS
                     QADIIDRFNVLETRHQQDRQKITSLTTELTALKEKLRTQDGDPQNRFTATGAASDQLA
                     DF"
     gene            6304..8055
                     /locus_tag="LSX49_004482"
     CDS             6304..8055
                     /locus_tag="LSX49_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase family protein"
                     /protein_id="HBL7170792.1"
                     /translation="MIQDAFVRQRARQLYWQGYPPAEISRLMGINPNTIYAWKKRDQW
                     DETPPVQRVTQSIDARLIQLTEKQNKTGGDFKEIDLLTRQLKKLHDGQPDVMAAGKKG
                     RAKKLKNHFTPEQIAALREKIISRLEWHQRGWFDSLTLCREAGIRNRMILKSRQIGAT
                     WYFAQEALLMALRDDVAQPYQRNQIFLSASRRQAFQFKSIIQKAAAEVDVELKGGDKI
                     ILSNGAELHFLGTSAASAQSYTGNFYFDEFFWVSRFAELRKVAGAMATLSGLRRTYFS
                     TPSTETHEAYAYWNGDRWNEKKASHKRQRFSVDWKTLHNGLICPDRTWRQIVTLEDVV
                     NHGWKHTDIDEIRDENTEDEFLNLYMCEFVREGESAFNLNILIGCGVDGYDDWKDWKP
                     FAPRPMGNRPVWIGYDANGSSGNGDSGAVSVVVPPAVPGGRFRTVETRRVQGLEFEEQ
                     ARVIEEFTCRYNVEHIGIDVTGGNGEAVYQIVKRFFPAAIPYTFTLSSKRSLVLKMLQ
                     IMRAGRWEYDRAERELVAAFNAVRKVKTPGGFITYETDRARGISHGDLAWATMLAVIN
                     EPIGGEGENERFMVMEF"
     gene            8055..9101
                     /locus_tag="LSX49_004483"
     CDS             8055..9101
                     /locus_tag="LSX49_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL7170793.1"
                     /translation="MSRKNKKVRMSSRIDLADALRKESSLSAFTFDGPYRLTGHDLLD
                     NMYCADNGRWYETPVDWYGLARAARQTSWHQSALYFKRNVLLGCYIPHPLLSRQDFSA
                     LALDWFVFGNAFLELRSNMLGEPLKLRHALAKYMRRGSDLESWWYVQDGKDAFQFRPG
                     KVCHLMNPDINQEIYGMPEYLGALLSASLSHSADMFRKLYYDNGSHAGCIIYIGAAQV
                     NRESMDSLKETLQGARGGGAFKNVLIHAPNGGKEGVQILPFQQITAKDEFMNVKAASR
                     DDVLAAHRVPPQLMGAMPGEKSAFGDVEKAARVYAINELMPVMEAMKHINDWLGEEVI
                     RFNSYALLDEKTAP"
     gene            complement(9116..9640)
                     /locus_tag="LSX49_004484"
     CDS             complement(9116..9640)
                     /locus_tag="LSX49_004484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170794.1"
                     /translation="MVINYKQLREKREQVKESFRRNEDLTPLVRLAQGIVDAYEISLE
                     LPSQTWTDSDGNRQHYVSCGLEAAEGFRRMPLSQIPAATPKARGSNDERKLTFSIETV
                     VDDTPGEVAFVHTPVSIAMYNDEIQVRVNNNIVPLKEGNSPYTTVCEAIQYYVLSEID
                     NLKPDGTQKMVQLW"
     gene            10364..10861
                     /locus_tag="LSX49_004485"
     CDS             10364..10861
                     /locus_tag="LSX49_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4760 domain-containing protein"
                     /protein_id="HBL7170795.1"
                     /translation="MNPITLQIISNAIVLLGVLVAIGTIIYNVRTAKKTQTANFLFES
                     RQDMQYIESLHTLKQVHRSGKSFRSYVFPCDGCIITDEEMAERRKFQYILNFYERVAV
                     SIREGIYDEKMIKRTSYTTVVETYDIAEPLIKAIRESINSDTTYQEFEWLVRRWKANP
                     LRKNK"
BASE COUNT         2442 a         2887 c         2960 g         2779 t
ORIGIN      
        1 tctgacaact gaattccgcc attcttaatg ctccagccct gcgcagcagc atctccggct
       61 gtcggcaaca gggagattgt gcgtacggat gcatcttcag acggccccga tggcgtgtcg
      121 ccgccgggcg agggtttgat ttccggtgcc ttaccactga tgaaggctaa ggtgcgaccg
      181 gctacgttca gaatagcggt tgccatacga tcgggaataa tgccacgacg cgcccatgag
      241 ctgaaatgcg tctggcgatt tgatgatacc cagtttttgt tcgttcggga tgccgaaccg
      301 taatatccct cacttgcagc atccggatct tccgttggtg cgttggtgga ggtattgttg
      361 ccactaccat cggtcaggaa cggcacaaag aaaacgttgt cgctctccct gtttttgtac
      421 gccccgtaaa tggtgtcgta ctgcgtgccg taggtgtttt tccagtaata cgtcgtgtca
      481 ccacaaatcc atggcacact tgccgctctg cctccatgac actgcgtgtt aaactcggta
      541 atgtccgcac gaaactgttt cagcatggcc gtaaacagcg gaggttgctg tgagtacgta
      601 gcggcgctca tgtcaaattc gccctgcatc cagcatacgg ccagcagcat gttttttggg
      661 tttttctgca atgcggcctt cgtgcgcaaa atcaggtcct gatataaagg tttacccaca
      721 ccccagcgag ccgaatcctg actggctcct gtggactcgc tgaatgtccc ctccgcgccc
      781 tgggtgaatg ccgaaccacc acgacagcat ggaaccagta aaatcccggc attctgtgga
      841 atgtaaggca acaggcgttt ggcaatatgc aagccctgtc cgacacagcc atactgccct
      901 ttgctcaggt ctgcattcgg gtgattcagt gcgctcatat cctgaacatc atgcaggcag
      961 tggtctgccg gaatgatgtc gttaaatgcg catgctttac caccgggagt cactgtgttg
     1021 cgacgggcca gttgcttaat gcgtgggtgg ggcgcatcgt aagaatccgg cagcggcatt
     1081 ccctcaccat atgacatggc attggattga ccagcaagta ccaccacgta ataccactcc
     1141 ggcacgctgc cgtgctgggg ggaatcaggt gagatgtctg tagtgccatc ggccaccatt
     1201 gcctgcatta gataccacgg ggtgccgggt tcgtaggcaa cccgcgtctc cccctgaaga
     1261 tgccaccctt tcgcaagatg ttcattcacc ttttgagtca gttcagcctg tgtcatggct
     1321 gtaatcagtg caaagttctt actggtcatt gtgttactcc cgtctggtgt gtcagttcgg
     1381 ctattctctt atccagttca gcaatggccc gtttatccgc gttacaggtt tccagtgcat
     1441 ccagaaggcg gtcgccccat attccgaggt ttccccatgt gggtgggtca gggaaggggg
     1501 gaggcgttac cggcatggtc agcgtctgcg gtataagccg gactgacggc gctggccctg
     1561 gcgcgttctg cgtgcctgcg caacctgtca gtaaaacgag cgtcaggcaa agcgtgggcg
     1621 cattcatctt ttgcaatatc gttgcgtagc tgttcacgtc ttacctctcc gtcctgattg
     1681 cgttgctgat tttccgcgcg gagctgagcc agcacctgct gcatatcctg taccccggcg
     1741 ctgatgatat tcagtgtgtc gacggtactt ttcagggtgc tggcctgcgc ttcgtttctg
     1801 gcgttctccc ggcccagcga ccacgacaga cgcatggatg taatcagaag gaaagcgacg
     1861 ccaagcgtgg gccagagctt catgccggat aggctccgtg tggtaactga aaatgcggtc
     1921 cgtctttcag ggtcttccag tcgccgcccc attccaccgg aatattcagt tcctggctgg
     1981 cctgtctgaa tgctgctgcg attttttcgt acagcggcca ttcccatgac acctggttgc
     2041 cgacataagc cacaacatcc acggcatgcc ctgtgagatg gcgactgttc atggtctggc
     2101 tcttgcctgt ggtcacgagc tgcttctgac gataacgact gcgcaatcct tcggtgatac
     2161 caaaatccac ttccgagatt tccagcgccc gtcgggtcac tttcaccaga tcaggattta
     2221 caccctgcaa attcttttcg ctccggctgc tgaatttaaa tgtgttgctc attcgttcct
     2281 ctccttcacc ctgcgatcaa atattgcaat aaccttgtcg cgtgctttct ctgcgcccat
     2341 aaaaccgatt gaggcaccaa aaaacgtcac tgcatcctca gggatcccga agaagcgcag
     2401 cgacccggcc acggccatgg caagaacgcc gcacgccagc gatcccgtta cggtctgaac
     2461 cagtgttcgt ccgtcataaa gactcatcag cgcggaaatg ctgaccgccg cgcctactgc
     2521 atacaccgtt ggcaggtggt caaagagcca cgcaataacc tgctctgtga tccctgtttg
     2581 aatggtgctc actgctactc cccccacaac tgaatcattt ctcgtttctt cttctccggc
     2641 tccggcatct ccacttcctg cccggcgtcc agaaatacct gctgacagag tccggggttg
     2701 gcatccagca ccttttcggt gacgccctgt gtcgtgccgt agtaccggaa acagagcgaa
     2761 tccacggtgt cgccttccag tgccttcact ttcatcagca cagctccgca aacattcgcg
     2821 gtcgtcccag aatgtcagag atggcccagc tcacatcgcg ccacaaatcc gatgtctgta
     2881 tatccagtgc gtccgcccgg cggtcgccct tgtccgttgt gtccgcatcg cggtaacgct
     2941 ccagaatcag ggcgcgtgtg gcggtataaa cagcattgcg ccagtgccag agattgacgc
     3001 tttctccgtt aattacaggg gccggaacat cggccagcgt ctgatagcca gccgcctgtt
     3061 gttcctgctg ccatgcttcc agctcgcggg taacgtgtgc tatggccccg gtggcggtat
     3121 gcagcaggcg ggaggtggtc acgcggcccg gcagtcgtac cgccagacgc agctcgcgca
     3181 gcacaatatc cggccagaat gcacccgctg aaatacgggt atcgccatca tcggtgtcgg
     3241 tgatgtcgtc ctctgcgggg ccggggttag ttctggcaac catactcatg gggttcactc
     3301 ctgaaaaaat cgggcggtgg gtgcgcggtg taaacggtca cggagtcaaa ccggaacacc
     3361 gcgcacgccg cccgctgacg gggtcagtcg ttaaccgcgc tttgccttct gcgtcgcggt
     3421 ggtttttcgt gttgcaggct tccgcgttgt ctttttactt ttgctgcttt cgtcctgcgc
     3481 ctgctgtgcg ctggcgtctt ctggttcggc tgcggaatcg gcttttttca gggcgcggga
     3541 aagggttgca atctcgcgtt tcacacctgc gttcgggttc aggtgcatcg cttcgcgcag
     3601 cagcttcagt gatgaggcca tgttgtctgc atcggtcagg ccacgacggg caaaggcaca
     3661 cgccttgcat aatttggcgc gcacttcgtc cggcatgtcc tggttggcga taatttccca
     3721 aagtgtgtcc agtggttcga taaaggcgga taaatccgcg tcggcatccg tcccagcctg
     3781 cgtcagtacc gggttgcaga tttcttcggt cagtaccgtg gcagcagtac ggccaaagtt
     3841 atccggcatg atgaggttgt gacggaccac atatgcacca atacgcagcg ccagcggaag
     3901 atcgccgcag tcaatcgccc acaccatcag cgtggcaatt acttcgtcct gttgcccgcc
     3961 gtcagcctcc agcgttccct caatccagcc ggaaaagtcc ggcaacaact cttttttgat
     4021 ggcggctttc gcgcttctgg cctgtatggc ctttagcctg gcctgtgcca gacgcagacg
     4081 atacagcacc tcttcatgcg cggtacacgc ggcgtggtcc acaccttcat tcgcccggcc
     4141 tgcgcgctgt gccatcacgt tctgccagtg ttgttgtgca ggagtaatca ttttttctct
     4201 ccgttacagg cgggcatgat gcccgccgtg agttgattag ctgtcggcga acttcaggcc
     4261 agtgaccatc gcgcacttgc catagtcttc aacgacataa gcgtcattga tggactggta
     4321 ggtggcgatg cggttgtatt ccggctcgtc tttcatcagg cgacgcattg aacctttctg
     4381 ccagtaaatc gacaggttgt tgaacgaggt gataagcatc gttgcatccg ggaagaacgg
     4441 cgcaaggaac acgcccagcc cgccaatggt gcgcgatgac aggatgagct gcccggcaag
     4501 taattccgca ttgggattct ggccgctgat gctgttcagc acgggcagac gcagcgagtt
     4561 aaacaggttg cgccccataa tcaccgcgag gtcgtcagct tccttgtgcc attcatccag
     4621 cagggatgag cgcgcatcct gtaccagagc atcggcattc gcatacttac ccgcgtgcgc
     4681 cacagtgttg tccatgttgc gggaggtcag cgtcacgtca ttcattacgc gctcgctggc
     4741 atcggttctg atgtgctcca gccagcccac gttaacgtcc tgaagcagct tgttggtgtg
     4801 aaaatcagac tcgtaggcgt gggatgtgcc gttaaagcca atcatgatgc gatcaagcgc
     4861 tacctgccgg gcgatctgtg tactgatacg ggactgaaaa tcgctgtggg ccgcccaggt
     4921 atcaagctgt gggtacgaaa taaaggtatc gtagttcacc tgttcgcact ggtactgacg
     4981 agacttcata tcgatcacgt tattcgggtt acggcgtttg atgccgtcat aactgctatt
     5041 cgtgcgcgca attggcccgg tggtgtccag gaggattttt tcgcctttct ggtcggtcac
     5101 gccgatcacg ttaattcttt tcgtaaattc ggtactttcc tttgaggcgt tttcaaaacg
     5161 ctgctgcacc gcgggttcca cggtaaatcg cgataccagt gcagataccg ggatattgtt
     5221 aagcgacgcc tgctgcgcca tatagcaacc cagcttgttg cgggtaatat ctgacatcac
     5281 cagattcata aaaaatttgc tcctttgtct tatcagaagt cagccagctg gtcggaggct
     5341 gcgcccgttg cggtgaagcg gttctgcgga tcgccgtcct gcgtgcgcag tttttccttc
     5401 aatgctgtca gctctgtggt cagtgacgtg attttctggc ggtcctgctg atggcgggtt
     5461 tccagcacat taaaacggtc gataatgtcg gcctgtgacg ttgcaacgcc ttccaccgct
     5521 tcctgaattc gggagaaact ggcgtcatcc gctttgcggc cacgaccaat aatccccatt
     5581 acgcggttaa accactgggt gccttcttcc tggcgttgtt ctgccatttc gatgatttca
     5641 gactcgatgg cttcggagat aagcggtgct tcaccctgga tactgttgaa cgtcatcacc
     5701 gcctgacgtt gctgtgccgt gaatttcagg cgctcagtgc ccaggcttgc cggggtgtcg
     5761 gtcatcgcca gcccgaccag ataggcgcgc ccgttaacgg agaactgcgg gtgcagttcg
     5821 atactggaat agattttctt gccgtcagcg acaagctgct tcatgcgctc ggtcggttcg
     5881 atttctgcat acagcgcagt acgtccggcc agcggacctt ccgtaatgtc ttccgtactc
     5941 agtgcggtga catcgcccat tgcggaaaat tcgcttgacg gacatggcga gagatagtgc
     6001 tcaacgttca cgcgggcagc gtaaacatcc gggttgaagt tctcggcggc ttcacgcaga
     6061 tgcaccggac tgatttcacg gccatcaaca gttgatccgg agacagccac gcgaaacttt
     6121 ttgcgggatg tctttttttc attagccata gtttttgccc ctctgactgg ttcttcagtc
     6181 atgatggcaa agcgtaacag gctgatacaa agggcttttg ttgtaagaaa acagtcagaa
     6241 cagagggtta aggagaacag tttcgcgcgc gggtaatctt cctgtaatta ctcaggggga
     6301 gcaatgattc aggacgcttt tgtgcgccag cgtgcgcggc aactttactg gcagggttat
     6361 ccgcccgcag aaatatcacg tctgatggga ataaacccga acacgattta tgcgtggaaa
     6421 aaacgtgacc agtgggatga aacgccaccc gtgcagcgtg tcacgcagtc catcgatgcg
     6481 cgcctcatcc agcttactga aaaacagaat aaaacaggcg gtgactttaa ggaaatagac
     6541 ctgctgaccc ggcagcttaa aaagctgcat gatggccagc cggatgtgat ggccgcagga
     6601 aagaaaggcc gggcgaaaaa actcaaaaat catttcacgc cggaacagat tgccgcactg
     6661 cgggaaaaaa tcatcagcag gctggagtgg catcagcggg gctggtttga ctccctgacc
     6721 ctttgcaggg aagccgggat acgtaacagg atgatcctga aatcccgaca gattggggcg
     6781 acctggtatt ttgcacagga agcactgctg atggcgctgc gtgacgatgt ggcgcaacct
     6841 taccagcgta accagatttt tttgtctgcg tcgcgtcgtc aggcgttcca gtttaaaagc
     6901 attattcaga aggccgcggc tgaagttgat gtggagctga aagggggcga taaaatcatc
     6961 ctctccaacg gcgcagagct gcattttctc ggcacttctg ctgcgtcggc acagtcctat
     7021 acgggcaatt tttattttga tgaatttttc tgggtcagtc gctttgctga actgcgcaag
     7081 gtggctggcg ctatggcaac cctcagcgga ctgcggcgca cctacttctc cacgccatcc
     7141 accgaaacgc acgaggcata cgcctactgg aacggcgacc gctggaacga gaaaaaggcc
     7201 tcgcataaac gccagcgttt ttctgtggac tggaaaacgc tgcataatgg gcttatctgc
     7261 cctgaccgga cgtggcggca aattgtcacg ctggaagatg tggttaatca cggctggaaa
     7321 cacaccgata tcgacgaaat tcgtgatgaa aacaccgaag acgagttcct caatctctat
     7381 atgtgtgagt ttgtccgcga aggggaatcg gcatttaacc tgaatatcct gattggctgc
     7441 ggtgttgacg gatacgacga ctggaaagac tggaaacctt ttgctccccg cccgatgggg
     7501 aatcgtccgg tatggattgg gtatgacgca aacggcagta gtggcaacgg cgacagcggc
     7561 gctgtgtccg tggtggttcc tccggctgtt cctggcggcc gttttcgaac ggtggagacg
     7621 cgacgcgttc aggggctgga gtttgaagaa caggccagag tcattgaaga gttcacgtgt
     7681 cgctacaacg tggaacacat cggcattgat gtgacgggcg ggaacgggga ggctgtttat
     7741 cagatagtga agcggttttt ccctgctgct attccgtaca ccttcacgct gtcatcaaaa
     7801 cggtcgctgg tactgaaaat gctgcaaata atgcgtgccg ggcggtggga atacgatcgc
     7861 gccgaacgcg agctggtcgc ggcctttaac gccgtgcgta aggtgaaaac accgggcggc
     7921 tttatcactt acgaaacgga ccgcgcgagg gggatcagcc acggcgacct tgcgtgggca
     7981 accatgcttg ctgtcattaa cgaaccaatt ggcggcgaag gagaaaacga gcgtttcatg
     8041 gttatggagt tctgatgagc agaaaaaata aaaaagtgcg catgagttca cgcattgatc
     8101 tcgctgatgc gctcaggaaa gaatcatcgc tcagtgcatt cacatttgat ggtccttatc
     8161 gcctgaccgg gcatgacctg ctggacaata tgtactgtgc tgataacggg cggtggtatg
     8221 aaaccccggt ggactggtac ggtctggcaa gagcagcccg gcaaacgtcc tggcatcagt
     8281 ctgcgcttta ctttaagcgc aatgtattac tcggttgcta catcccgcac ccgctgcttt
     8341 cccggcagga tttctcggcg ctggcgctgg actggtttgt gttcggtaac gcattccttg
     8401 agcttcgaag caatatgctc ggcgaaccgc ttaaattacg gcacgccctg gcgaaataca
     8461 tgcgacgcgg aagcgatctt gaatcatggt ggtatgtgca ggatggcaag gacgcgtttc
     8521 agtttcgtcc tggcaaagtg tgccacctga tgaatccgga tattaaccag gaaatctacg
     8581 gcatgccgga atatcttggc gcattactct cggccagcct ttctcattcg gcggacatgt
     8641 tcagaaaact gtactacgac aacggatccc acgccgggtg catcatctac atcggtgcag
     8701 cgcaggtaaa ccgcgaaagc atggactccc tgaaagaaac gctacagggg gcacgtggtg
     8761 gtggtgcgtt taaaaacgtg ctcattcatg cgcccaacgg gggcaaagag ggggtgcaaa
     8821 ttttgccgtt ccagcagatc accgcaaaag atgaattcat gaatgttaag gcggcatccc
     8881 gtgatgatgt gctggctgcg caccgcgttc cgccgcaact gatgggggcg atgccgggcg
     8941 aaaaaagtgc gtttggcgat gtggagaagg cagcgcgggt ttacgcaatt aacgagctga
     9001 tgcccgttat ggaggctatg aagcacatca atgactggct tggcgaagag gtgatccgtt
     9061 ttaactctta tgctcttctt gatgaaaaaa cagccccgtg atggggctgt cctttttacc
     9121 agagttgaac cattttctgg gtgccgtcag gcttgagatt atcaatttca gagagaacgt
     9181 aatattgaat ggcttcacaa acggtggtgt agggtgaatt accttcttta agtggcacga
     9241 tattattatt aacgcgaacc tgtatttcat cgttatacat tgcgatcgaa acaggagtgt
     9301 gcacgaacgc gacttcgcca ggtgtgtcgt caaccaccgt ttcaatacta aaagtcagtt
     9361 ttcgctcatc attgctgccc cgtgctttgg gggtagcggc agggatctgg gataaaggca
     9421 ttctgcgaaa tccttcggct gcttccagtc cgcatgaaac gtaatgctgg cgattaccgt
     9481 cgctatctgt ccaggtctgt gatggcagct ccagcgagat ttcataagca tcaacaatgc
     9541 cctgggcaag gcgtacaagc ggggtcagat cttcattgcg gcgaaagctc tcctttacct
     9601 gctcccgttt ttctcttaac tgcttgtaat taatgaccat aagacagcct ccattgattt
     9661 ctttgctcgt attttgcact tatgaagtat ggtcggcaag gtgccgtatc gctgacgcgc
     9721 ttcgcttgtc tgctgcttcg ccggggcata aaaaatttat gccccggctc tccagctcct
     9781 gtatcaatca gataatttca cgacgccttc cagtttatcg ccaccatcga cggtcagact
     9841 cttacgcaat tccaccgcgt tgactgcatg ttctcgctgc ctcagtgcga ttttgacggc
     9901 cttacctttc accccatcaa atcaaaagcc ctcacgcctt tttcatgctc agcgtgagaa
     9961 atatggccat tctgttgtgt ctctgcgaca tcgttcaggg aatgctattt accccctgaa
    10021 acgcgggctg ttcccccgtc acctgcgcgc agaaaaagcg cgtttttttg tgcacgcacg
    10081 gatccttgac ggatccagcc gccatgcggg ccggaagggt aaaaagtcgt tcaaaaaaat
    10141 tgtgcaaatt tgtgcacttt tgtgcaggta agcatgccta tatatttgac cgtggcttgc
    10201 ctttgatgta gtttatacgt cacaaaaacc acaaaacgtg gttatgattt ctatgagggg
    10261 gttgatatga aaaaaatgta tgatgaattt gatggtttct aagctacgtt gacctctaat
    10321 gaggcgggga tttgctcccc gcctttttta tggatgaaat aggatgaacc caataacact
    10381 acaaatcatc agcaatgcta ttgttctgct tggcgttttg gttgccattg gaaccattat
    10441 ctacaatgtg cgtaccgcaa aaaaaactca aacggccaac tttctttttg agagtcggca
    10501 agatatgcaa tatatagagt cattgcatac cctgaaacaa gtgcatcgtt caggcaaatc
    10561 atttcgttct tatgtttttc cttgtgatgg ttgcataata acagatgaag aaatggccga
    10621 gcgtcgaaaa tttcaatata ttttaaattt ttacgagcga gttgctgtaa gtattcgtga
    10681 aggtatttat gatgaaaaaa tgataaaaag aacatcttac acaacagttg tagagacata
    10741 tgatattgcc gagccattaa ttaaagcaat cagagaaagc attaattcgg atactacata
    10801 tcaagaattc gaatggttag taagaagatg gaaagctaat cctttacgga aaaacaaata
    10861 atgttttacc ctttaattta caagtaacac agggggaagt gtgacacaga atccgttttc
    10921 attttatgac tttttgggct atctaattcc aggtgggtta ttcctgttta tccttttttt
    10981 gttttctatt gaaattaacc ctgtttatat agaaggtatt cttaaccata tcctgaaata
    11041 taaagaaata ataagtgtat ttatatat
//
LOCUS       DAFGPF010000146        10931 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFGPF010000146 DAFGPF010000000
VERSION     DAFGPF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10931
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.146"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            39..833
                     /gene="hyxR"
                     /locus_tag="LSX49_004486"
     CDS             39..833
                     /gene="hyxR"
                     /locus_tag="LSX49_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator HyxR"
                     /protein_id="HBL7170796.1"
                     /translation="MKKPLVIISACQFTRLALESLIPTDRYIVRVYSNVTTEVEFVLK
                     TSCGYLLADIPSLPSGELVLLACLARLRSDAGQWQVCLTGDSDWFDNAPAASLYNGFP
                     RIGTMLTASRYQNQIIRWLLRPLPGDMSDFWLLTARELSVLKILMQGMSFSEIARYEQ
                     RSSKTLHAIATRALMKLGLRTLSDFRLLYTGCGDSRVKRNIRLHAKYIGQHSAHRLTQ
                     YVQNMVSGILYPEKVAVGESINSDAISGKVLSGQRKNISKKRPGLL"
     gene            987..1748
                     /gene="hyxA"
                     /locus_tag="LSX49_004487"
     CDS             987..1748
                     /gene="hyxA"
                     /locus_tag="LSX49_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein HyxA"
                     /protein_id="HBL7170797.1"
                     /translation="MRFVLFCPSGIVPAQFAALSTGSVGNVTCIRTEEELRNKLRHRP
                     QSVVISAGRPAECAEMWFRFYLDHSFVVVLCVAPFFLPPDVSISGVLKNLRLLKPGMS
                     VERVISIANASGGFSGLKHAENLPVMDCYSVFMKEVNNRTKTIVMSERFPEKQKKVLS
                     LLLAGHSWEYSAQFLKTGIRQIWLAEQSLKKRWGIPDSMSLREALLLSSNNFHGDGNA
                     LETTNAMTLRENGNTNRYSVVVNAGTQALSLHKYK"
     gene            1790..2866
                     /locus_tag="LSX49_004488"
                     /pseudo
     CDS             1790..2866
                     /locus_tag="LSX49_004488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            2888..4081
                     /locus_tag="LSX49_004489"
     CDS             2888..4081
                     /locus_tag="LSX49_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7170798.1"
                     /translation="MTKATVNTGTFASQNGTLIVDASSENTLDISGKASGDLSVYSAG
                     SLDLINEQTAFISTGKDSTLKATGTTEGGLYQYDLTQGADGNFYFVKNTHKASNASSV
                     IQAMAAAPANVANLQADTLSARQDAVRLSENDKGGVWIQYFGGKQKHTTAGNASYDLD
                     VNGVMLGGDTRFMTEDGSWLAGVAMSSAKGDMTTMQSKGDTEGYSFHAYLSRQYNNGI
                     FIDTAAQFGHYSNTADVRLMNGGGTIKADFNTNGFGAMVKGGYTWKDGNGLFIQPYAK
                     LSALTLEGVDYQLNGVDVHSDSYNSVLGEAGTRVGYDFAVGNATVKPYLNLAALNEFS
                     DGNKVRLGDESVNASIDGAAFRVGAGVQADITKNMGAYASLDYTKGDDIENPLQGVVG
                     INVTW"
     gene            4265..4933
                     /locus_tag="LSX49_004490"
     CDS             4265..4933
                     /locus_tag="LSX49_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170799.1"
                     /translation="MNEQIKQDIDLIEILFYLKKKIRVILFIIAICMAMVLLFLYINK
                     DNIKVSYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFQTSPDVKNREIK
                     LEWSGDKRDLPTAEAEISRVQASIIKWYTSEYHNGRQVLDEIQTPSAINSELYTKMIY
                     LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQ
                     NSGQ"
     gene            complement(5176..5871)
                     /locus_tag="LSX49_004491"
     CDS             complement(5176..5871)
                     /locus_tag="LSX49_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HBL7170800.1"
                     /translation="MDNRSEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLTQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGIENISQAEQAIVGVVYAEYGLTESGGVVLFSAAGRGRSLSLLP
                     ESSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     gene            complement(5864..7291)
                     /locus_tag="LSX49_004492"
     CDS             complement(5864..7291)
                     /locus_tag="LSX49_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="HBL7170801.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFAKTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDSVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQENKNG"
     gene            complement(7302..8021)
                     /locus_tag="LSX49_004493"
     CDS             complement(7302..8021)
                     /locus_tag="LSX49_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HBL7170802.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAE
                     KVAARMQDLTSFIVNTLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            complement(8547..9401)
                     /gene="rclR"
                     /locus_tag="LSX49_004494"
     CDS             complement(8547..9401)
                     /gene="rclR"
                     /locus_tag="LSX49_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RclR"
                     /protein_id="HBL7170803.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFVAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMMEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSREMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     gene            9628..>10931
                     /locus_tag="LSX49_004495"
     CDS             9628..>10931
                     /locus_tag="LSX49_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HBL7170804.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKQLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGRRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLN"
BASE COUNT         2987 a         2551 c         2524 g         2869 t
ORIGIN      
        1 aatgtcaggt tttgtagcaa tggcgtggac gagtctgaat gaagaagcct ctggttatta
       61 tcagtgcctg tcagttcacc aggctggcac tggagtctct catcccaacg gacaggtata
      121 tcgtgcgggt gtacagcaac gtcactacag aggttgaatt cgttttaaag acctcctgtg
      181 gctacctgtt agctgatatc ccttcgcttc cttcggggga gttggttctt ctggcttgtc
      241 tcgcccgttt gcggagtgat gccgggcaat ggcaggtctg cctgaccggt gactccgact
      301 ggttcgataa tgctcctgct gcaagtctgt ataacggctt cccacgcatc ggcaccatgc
      361 tgacagcgag tcgttatcag aatcaaatta tccgctggtt actgcgtcct ttgcccggcg
      421 atatgagcga tttctggctc ctgactgcac gggagttgag cgtgcttaag attctgatgc
      481 agggcatgag tttcagtgag attgcccgtt atgaacaacg cagttcaaag accctgcatg
      541 cgattgccac acgggcttta atgaaacttg gactgagaac actgagcgat ttcaggctgc
      601 tctatacggg atgcggtgac agcagagtga aacggaatat acggctacat gcaaaatata
      661 tcggacaaca ttccgctcat cgactcactc agtatgtgca gaacatggta tccggaatcc
      721 tttatccaga gaaagttgcc gttggtgaat caataaattc tgacgccatt tccggaaaag
      781 tactttccgg acaaagaaaa aatatatcta aaaaaagacc aggattgtta tgacacagca
      841 gcgttgttac taccacccac tgcggcgcac acggactcgc tacagtgtag gagccaaaat
      901 atttctactg ttctgggctg caggattggg aggcatgctg tacagcctgt acagcgtgct
      961 ggcgtactga catctgtgag ggaaggatgc gtttcgttct tttctgtccc tcaggaattg
     1021 taccagcgca gttcgcagct ctatcaaccg gttctgtcgg caatgttacc tgcataagaa
     1081 cagaagagga gttacgcaat aaattgcggc acaggccaca gagtgtcgtg atatcggcag
     1141 ggcgacctgc cgaatgcgct gaaatgtggt tccgatttta tctggatcac tcattcgtgg
     1201 tggtgttgtg cgtcgcgccc ttttttctgc caccggatgt gagtatttct ggcgttctca
     1261 aaaacctgag gttactgaaa ccaggaatgt cagtagagcg tgtcatcagt attgcaaatg
     1321 cctctggtgg gttttcagga ctgaaacatg cagaaaattt gccagttatg gactgttact
     1381 ctgtctttat gaaagaggtg aataaccgca caaagacaat cgtcatgtca gaacgcttcc
     1441 cggaaaagca aaagaaggtg ttgtcgttgc ttcttgccgg acacagctgg gaatacagtg
     1501 cgcagtttct caaaacgggg ataagacaga tatggcttgc cgagcagtcg ctaaaaaagc
     1561 gttgggggat accggacagc atgtcattgc gggaagccct gctgctgagc agcaataatt
     1621 ttcacggtga tggaaatgca ttggaaacaa cgaatgccat gacattgcgt gaaaacggaa
     1681 ataccaacag gtattccgtg gtggtaaatg cagggacgca ggctttatct ctgcataaat
     1741 ataaataagt gggaaattga aattagttac cagaatggag aatttcttca tgaaaaacag
     1801 taaggcattt taccgcagcg cattagcgac agctattgtt atggctcttt ctgcaccagc
     1861 attcgctgct gataacgcgg tatcaactac accggttaca ttggataaag ataagacaac
     1921 tctggaacaa gatgttgtta ttagtggtac tacacagatt acagccgcaa caattaatgc
     1981 gaaagataaa gaccttaatg ttactttggg tggtcatgat attaccgcca catcaacggt
     2041 agaccaaggt ttcgttgaag gtgtaaaagt tagcggtgac aaaaatgttg tgattaatgc
     2101 tacaggctcc accatcacag ctcaaggtga aggtacctat gtccgaactg caatggtcat
     2161 tgattcaact ggcgatgttg ttgttaatgg cggtaacttt gttgcaaaaa atgaaaaaag
     2221 tagtgcgaca ggtatatctc tggaagcgac cacgggaaat aatttaacgc tcaatggcac
     2281 aaccataaat gctcaaggta ataagagttc cagcaacggc tctacggcaa tttttgctca
     2341 aaagggtaat ttgttgcagg gttttgacgg tgatgcaacc gacaacatca cccttgctga
     2401 ctcaaatatt attaatggtg ggattgaaac aatagttatt gccaaggaga ataagggaat
     2461 tcatacagtc aacctgaata ttaaggatgg ctcaataatt ggggcggcta ataataaaca
     2521 aacaatttat gcctctgctt cggcacaagg cgcaggttca gcaacgcaaa atttaaattt
     2581 gtctgttgct gattcaacca tctactctga tgtcctggcc ctttctgaaa gcgagaattc
     2641 agccggtacc acaacaaatg taaatatgaa cgttgcccgc tcttactggg aaggtaatgc
     2701 ttatacgctc aatagcggcg ataaagcggg tagtgatctg gatataaatc tttccgatag
     2761 ttcagtctgg aaaggcaaag tttcaggggc aggagatgcc agtgtatctc tgcaaaacgg
     2821 gtctgtctgg aatgttacgg gttcctcaac tgttgatgct ctggcagtaa aagacagtac
     2881 ggttaatatc acgaaggcta cagtcaatac tggcacgttt gcttctcaaa acggcactct
     2941 gattgttgat gcctcttctg aaaacactct ggatatcagc ggaaaagcga gcggtgactt
     3001 gagtgtttac agtgcgggtt cattggatct tatcaatgaa caaacggcat ttatttctac
     3061 cggcaaagac agcactctaa aagccacagg cacaacggaa ggtggtctgt atcaatatga
     3121 cctgacacag ggagctgatg gtaactttta tttcgtaaaa aacacgcata aagcatccaa
     3181 cgccagctcc gtgattcagg caatggcagc tgctccggct aacgtcgcta atctgcaggc
     3241 tgacacgctc tccgcccgtc aggatgctgt ccgtctgagc gaaaatgaca agggtggcgt
     3301 atggattcag tactttggcg gtaaacagaa acataccacc gcgggaaatg catcctatga
     3361 cctggatgta aatggtgtaa tgctgggtgg tgatacccgc ttcatgactg aagatggtag
     3421 ctggctggcc ggtgtggcga tgtcttctgc gaaaggtgac atgactacca tgcagagcaa
     3481 aggtgacact gaaggttaca gcttccacgc ttacctgagc cgccagtata acaacggtat
     3541 cttcattgat actgctgcac agtttggtca ctacagcaac acggcagatg ttcgcctgat
     3601 gaatggtggc ggtaccatca aagctgactt taacaccaat ggttttggtg cgatggttaa
     3661 aggcggttac acatggaaag acggtaatgg cctgtttatt cagccatatg ccaaactgtc
     3721 tgctctgact ctggaaggtg tggattatca actcaacggc gtggacgttc attctgacag
     3781 ctataactct gtgctgggtg aggccggtac gcgcgtgggt tatgacttcg ctgtgggcaa
     3841 cgcgaccgtt aaaccttatc tgaatctggc cgcactgaac gaattctctg atggcaacaa
     3901 agtccgtctg ggtgatgagt ctgtcaatgc cagcattgac ggtgcagcat tccgcgtggg
     3961 tgcaggtgta caggctgata tcaccaaaaa catgggagca tatgcaagcc ttgactacac
     4021 caaaggtgac gacattgaga acccgctaca gggtgtagtt ggtatcaatg tgacctggta
     4081 agaataaagc agtcggttcc cctgtcgact gttatacccc ctgcaggcag cagtatgctg
     4141 cctgcaggct ataaatatcc agtactcatg atgctggctt tttgctgata tttaccctga
     4201 acattcctga tacagactat taatacaacc ttatctgcga cagatttcat tttctggata
     4261 tattatgaat gaacaaatca aacaggatat cgatctgatt gagattttat tttatctgaa
     4321 gaaaaagatt cgtgttatcc tttttattat agctatctgt atggcaatgg tgctgttgtt
     4381 tctgtatatc aataaagata atataaaagt gagttacagc ctaaaaataa atcagacaac
     4441 accaggcata cttgttagct gtgatagcaa taataacttt gcctgtcaga ccacaatgac
     4501 tgaagatgtt attcagcgaa ttactacatt ttttcagacc agcccagatg tcaagaacag
     4561 agaaataaag ctggaatggt caggagataa gagagattta ccaactgctg aagcggaaat
     4621 atctcgcgtg caggcgtcta tcattaaatg gtatacgtca gaataccata atggcaggca
     4681 agttctcgat gagatacaaa cgccttcagc aattaacagt gagctttata caaaaatgat
     4741 atatctgacc aggaactggt cactgtatcc gaacggtgat ggctgtgtca ctataagctc
     4801 accagaaata aaaaataaat accctgctgc catttgcctg gctctgggat tttttctaag
     4861 tattgtgatt tctgtaatgt tttgccttgt caaaaaaatg gtagatgaat accaacaaaa
     4921 ctctgggcag taataaacag cattctgaca gagagtgcct gtataaaact atagtgacag
     4981 tgaccgggaa gggagcccgt cttcaggaat ggattcctgt ctttttaact gtaaatatcc
     5041 tggcattatt aatgtcagga tatttacaga agagcagcat aaccatgacg gaacggggtt
     5101 aagtcaggtt gtccttaacg ctattcacaa cctcgtatac cgccttcagg tttatgtcca
     5161 gactacatat ctctctcagc aatcctcaat aatcagatac accgctttca ccggaccatg
     5221 aaccccgacg actttgataa gctcaatgtc cgccgttgaa ctgggaccac tgatgatgtt
     5281 aatacatgac ggcattcgtt caccggcctg cgctttctga tgcaattttt ctgcaagttg
     5341 cgctacacgc ggcaggattg tgcttttacg caggataaaa agagaagatt ccgggagcag
     5401 gctcaatgaa cgcccgcgcc cggcggcgga aaaaagaacc acgcctcccg attcggttaa
     5461 accatattca gcatatacga cgcccactat agcctgctct gcttgtgata tgttctcaat
     5521 acctttcgcc ggatcccaaa caacggcatt gcattcctgc tgcaaacgtt cgctaatccc
     5581 caattcctcc agcctcgtgt caccgctaat cacgaccgac tgatctccca gctctttaca
     5641 cagacgtatt gcagcttctg ccgccttcgc ctcgctggtc agttcacagc gcgtcaacat
     5701 aacatcgctg gcaaactgga taaacgcgtc acagcgctgt tgttgggtaa gttgggtaag
     5761 ccgctcgtta gcatagttgt taagcggcgc atcttctgct tgcggttcaa gtcgcagcgg
     5821 gcgacccagt gcctgagcaa cgttattcaa aaattcgctc cgattatcca ttcttattct
     5881 cctgcgcctg atgtttctta aaccaactac ggaaactctc tccgtcagct tcaggaagat
     5941 cgcgtgcttc catccagtcg ctaatcgcgc caaatttgag tggtgttttg ccgccattga
     6001 taaaccagct tgccgcatga gcaccagcca tcatcccaac tttccacaat cctggatgac
     6061 tattggcata agcgaacatt tttatcgccc gttgctctgc ttttgcggtg atcccttttt
     6121 cagccatcac ccgacgatga cgcaaaatca gttttgacag cggaatacgc accggacaca
     6181 cgctgtcaca agcggtgcat aaagagcagg cgtagggtaa atctttaaaa tctttatagc
     6241 cgccaagtaa cggggaaatc accgcaccaa ttggccctgg ataaatagag ccatatccat
     6301 gaccgccaat atggcgatat gccggacaag tattcataca agccccgcaa cgaatacagc
     6361 gcagcacatc ccgaaattca gaggccagca cctcagaacg cccgttatcg acaataacca
     6421 gatgaaactc ttcaggacca tcaacgtgcc ccgcttcgcg tggtcctgtc agccaggtgt
     6481 tgtatcccgt caaacgtgca ccaacggcac tgcgcgccag catggtgatc aatacatcta
     6541 cctctgcaaa cgtgggagca atacgctcca ttcccatcac tgcaatatgc gttttaggca
     6601 gcgtggtaca cattcgcgca ttaccttcat tggtcaccag gcataccgaa ccggtctctg
     6661 ccaccgcgaa attacagccg gtaataccta tttcagcact gaggaaatct tcgcggattt
     6721 tttgccgaat gaataaggtc atcgcttcag gcgtttccgg cccctcatag cccagacgtt
     6781 cgtgtagcac tcgacggatc tgatggcgat ctttatgaat tgccgggacc acaacatgag
     6841 agggcggatc ttgatccagc tggagaatat attcacccag atcggtttca atcacctgaa
     6901 tcccggcatc ctgcaacaca tgattgacac caatctcttc ggtcaccatc gatttagatt
     6961 tcactacctt ccgggcattt ttgcgttggg caacctgtaa aatgtagcgg gtggcgtctt
     7021 ctttggtttt tgcaaaatag acgtgaccgc cgttttgtgt cactttttct gagagctggt
     7081 acagataagc gtcgagatta ctcagaacat gatcacgtat ctgggcggcc cgatcgcgcc
     7141 actcctccca gtgccccaat tcatcgacca ttttttgccg atttgcccca atacgctgct
     7201 gcgcgtttgc caccgctttg cgcatgatcg gatcttcaat ttgctgacgg atgcgtgtct
     7261 taaaatctgt attactggtt ttgatcgaca tctttatatc ctcagcggct catcagcact
     7321 tcagcaatat gcatcacttt gactttctgc ccttcccgtt gtaatcgtcc actgatgttc
     7381 agcaggcaac tcacgtcagc accaattaaa tactcagggc ggacttccat caggtgcgca
     7441 accttttctt tcaccatctc gccggatatt tcggccattt tgaccgagaa cgtgccgcca
     7501 aatccgcagc aggtatcctg ttcagcaaag gtcaacagct ccagtccacg cacatttttc
     7561 agcagcgtaa gtggttcgtc cttcaccccc agcttacggg ccaggctaca agatgggtga
     7621 tacaccgctc tcccttgcaa actggcacct acatcgacta cccctaatgt attaacaata
     7681 aaagaggtga gatcctgcat acgcgcggca accttttcgg cacgtgatgc ccattcaggt
     7741 tcatccgcca gatacgtcgg gtaacttttt acggcatagg tgcaagagcc agccggtgaa
     7801 ataatgggat cgtcgttatc ctccagtgcg gcgatcagat ttttcatccc tggaatcgct
     7861 tctttgatat aaccactatt gatcgcaggc tgaccgcagc atccctgttt ctccgggaaa
     7921 tttacgcgac agccgagttt ttccagtagc agcacggagt ctcgtgccat tcttgatttc
     7981 agggcgtcac caatacaggt gacaaagaaa ttgacattca caactaatac tccattactt
     8041 catgcccatt tatgcccgat ggttccctcc ttccggggga tcaatcatca ataaatatgg
     8101 cgttcttttt taattggcta gcaacatacc acctctcatt tgtatgacaa atgataatct
     8161 ttcatctaaa cttcaaatgc aataactaat tttatttctt tcggcatcgc tcacatttta
     8221 tagggaaatc gacgatcatt tttggcataa gaaatccatt taaaaaggct acatccctta
     8281 tacctattca gagctactta ttcaggggtt attgagatat acactgatgg tgtacaaaaa
     8341 aatcaccgac aataatcacg catcaagtaa tagtcgggat tttatttaat tgaagcaatt
     8401 tagtttgcat ttttatttaa aaactgagct agagtccatc aaaaaaatat ataaaaccca
     8461 aaaccaccgt tagaaataga aatagttgaa aggctcacaa ctcccggaat gcggattatc
     8521 tttgccctga tttctggcgg ttttattcag ggtgcaagct gtctcaccct ttcccgatat
     8581 tctcccggag tacaaccaaa ctcgcggaca aacgccttgt gaaaagatga ttcactggca
     8641 tagcctactg actcagcgat caccacaaca gggagcattt cccgggaaaa catctgggcc
     8701 gctatttgta gacgcaactt tgttaataca gccagcggcg tggttccgga aacatcacgg
     8761 aaaagctggg caaaacttgc ccgggacatg tgggcgatgc tggccagcga ttcgacggtc
     8821 caggcgtgtc caggcatttc catcatttgc tgtattaccg caccaagacg tggatgcaga
     8881 agcaaactga gaatgttttt ctctgtatta acctgtgcaa tccactcacg caccgcgagg
     8941 gtaaagaatg tagcgcagat ctggctacac agagcatcca ctcccggcat tgccgatctg
     9001 gattcctgtt gtaaaaacgg gatcgcctcc ctcagccagt tatattccac gctatggttc
     9061 actggtgcta caaacagcgt ttccggcaaa gacgttaaaa aataacgcgc cgaatgttgc
     9121 agccgaagag ttccacagac aatacaggtc gattcattat cgacatgact caggcgatga
     9181 gctgaatttt gtggtagcag gaccacattt cccgggcgta atgtaaaaat ctctcccgtc
     9241 ggcatttcca gcttcgccgc tccttgcgtt aacgcatgcc aacgaataac cgacaactcc
     9301 ccggcaccat gtggaagttg ccagtcactt cctaacacgc aattcttatc gatcgttcct
     9361 tgtggagcgt taagcatcaa caaacggcta agagcatcca tatcagactc ctgagtggtt
     9421 tttggattac aaacaccaac aatcttagtc aataattaat ctaataccat caaatagtta
     9481 atcatgattt ttgttttgtg attctgatta agaaaaagaa aataccagac gataagacaa
     9541 aatatcaagc gttgtgaaga aatgttattt gctcttttgc gtctatagtc atgatgtcaa
     9601 atgaacgcgt ttcgacagga aatcatcatg aataaatatc aggcagttat tattggtttt
     9661 ggcaaggctg gaaaaacatt agccgtcacg ctggcaaaag caggttggcg tgtggctctc
     9721 atcgaacaat caaatgcaat gtatggcggg acctgtatta atatcggctg tatcccaacc
     9781 aaaacattgg ttcatgacgc acagcagcac acagattttg tccgtgccat acagcgtaaa
     9841 aatgaagtgg ttaatttttt acgtaataag aattttcata atcttgcgga tatgcccaat
     9901 atcgacgtga tcgacggcca ggcggagttt atcaataatc atagcctgcg tgttcatcgg
     9961 cctgagggaa atctggaaat tcatggcgag aaaattttta ttaataccgg tgcacaaacc
    10021 gtggttccgc caattcctgg aattaccacc acgccaggag tatatgacag caccggatta
    10081 cttaatctaa aagaattgcc tgggcattta ggtattttgg gcggcggata tattggcgtt
    10141 gagttcgcct ctatgttcgc taattttggc agcaaagtaa ccattttaga ggcagcttcg
    10201 ctgtttttgc ctcgggaaga tcgggatatt gctgataata tcgcgacgat tttacgcgat
    10261 cagggcgtcg atataatcct caatgcccat gtggagcgaa tcagtcacca tgaaaatcaa
    10321 gtgcaagtgc atagcgaaca cgcccaactg gcggtggatg cactgttaat agcttccggt
    10381 cgtcaaccgg ctaccgcttc gttacatcca gaaaatgcag gtatcgcagt aaacgaacgc
    10441 ggggcaattg tcgttgacaa gcaattacat accaccgcag acaatatttg ggcgatggga
    10501 gatgttaccg gcgggctgca atttacttat atttcactgg atgattaccg cattgtgcgt
    10561 gatgagttgc tgggagaagg cagacgtagt actgatgatc ggaaaaatgt gccttattcc
    10621 gtattcatga caccgccact gtccagggtt ggtatgacag aagaacaggc cagagagagt
    10681 ggtgctgata ttcaggtggt gacattgcct gtagctgcaa ttccgcgtgc cagagtgatg
    10741 aatgatactc gtggggtatt aaaagcgatt gttgataata aaacccaacg tatattaggg
    10801 gcatcactgc tgtgtgttga ctcccacgag atgatcaata tagtgaaaat ggtgatggat
    10861 gccgggctgc cttatagcat attacgcgat cagatattta ctcatccgtc gatgagcgaa
    10921 tcactcaatg a
//
LOCUS       DAFGPF010000147        10913 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFGPF010000147 DAFGPF010000000
VERSION     DAFGPF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10913
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.147"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(25..816)
                     /locus_tag="LSX49_004496"
     CDS             complement(25..816)
                     /locus_tag="LSX49_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /protein_id="HBL7170805.1"
                     /translation="MMKNTGYILALCLTASGHVLAHDVWITGKQAENNITAEIGYGHN
                     FPSKGTIPDRRNFFENPRIYNGKETITLKPASTDYVYKTESASKDNGYVLSTYMKPGY
                     WSRTSSGWKPVSREGRNDVAYCEFVTKYAKSFIPGEQQMPAQLYQSPTGHELEIIPLS
                     DISRFSEDVKLKVLYKTSPLAGAIMELDSVSYLKSSRHTHAVEHKHPVHKAELTFVTN
                     EDGIVTVPSLHIGQWLAKVQNKKSFQDKSLCDETVDVATLSFSRN"
     gene            complement(823..2793)
                     /locus_tag="LSX49_004497"
     CDS             complement(823..2793)
                     /locus_tag="LSX49_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent
                     hemoglobin/transferrin/lactoferrin family receptor"
                     /protein_id="HBL7170806.1"
                     /translation="MYMNVIRNVICTLIILPIGLQAETSHSSMAKDTITVVATGNQNT
                     VFETPSMVSVVTNDTPWSQNAVTSAGMLKGVAGLSQTGAGRTNGQTFNLRGYDKSGVL
                     VLVDGIRQLSDMAKSSGTYLDPALVKRIEVVRGPNSSLYGSGGLGGVVDFRTADAADF
                     LPPGETNGLSLWGNIASGDHSTGSGLTWFGKTGKTDALLSVIMRKRGNIYQSDGERAP
                     NKEKPAALFAKGSVGITDSNKAGASLRLYRNNTTEPGNPTQTHGDSGLRDRKTVQNDV
                     QFWYQYAPVDNSLINVKSTLYLSDITIKTNGHNKTAEWRNNRTSGVNVVNRSHTLIFP
                     GAHQLSYGAEYYRQQQKPEGSATLYPEGNIDFTSLYFQDEMTMKSYPVNIIVGSRYDR
                     YKSFNPRAGELKAERLSPRAAISVSPTDWLMMYGSISSAFRAPTMAEMYRDDVHFYRK
                     GKPNYWVPNLNLKPENNITREIGAGIQLDGLLTGNDRLQLKGGYFGTDARNYIATRVD
                     MKRMRSYSYNVSRARIWGWDMQGNYQSDYFDWMLSYNRTESMDASSREWLGSGNPDTL
                     ISDISIPVGHGGVSAGWRAELSAAATHVKKGDPHQAGYAVHSFSLSYKPVSVKGFEAS
                     VALDNAFNKLAMNGKGVPLSGRTVSLYTRYQW"
     gene            3075..3511
                     /locus_tag="LSX49_004498"
                     /pseudo
     CDS             3075..3511
                     /locus_tag="LSX49_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4036..4308
                     /locus_tag="LSX49_004499"
     CDS             4036..4308
                     /locus_tag="LSX49_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin biosynthesis transcription regulatory
                     family protein"
                     /protein_id="HBL7170807.1"
                     /translation="MTPSPYPRNNFNTELIQSCMNGEHFSLLIEISPIRSKKNIMALK
                     EYLVDGYSKQESCERNNVSISYFCLCLKKLNYTHSIVSALKYFYRE"
     gene            4754..4929
                     /locus_tag="LSX49_004500"
                     /pseudo
     CDS             4754..4929
                     /locus_tag="LSX49_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612254.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(5155..6324)
                     /locus_tag="LSX49_004501"
     CDS             complement(5155..6324)
                     /locus_tag="LSX49_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170808.1"
                     /translation="MNQKWKTLIVSVLTPSSIISGIALIVLWGYFSRLDRLDIFFDVM
                     NIKSILVLVCCTTILSLIMIIFIFFITSFFIPIVIPYDIKNLPAYNKIQGNFLSVMML
                     SGLFPMAFIYVLYCAFDFDQSVKDNSGWLSILSIGVLIVVISAIINTRYLEYDLSFKN
                     NRMKLLRRVQIYLIIPLSIALLVHLQVIPLEMVFRNIETSDKSINFKVIAELAFMSYF
                     IFILTILPGLIYLKMNPQHKLSKRISSAFVASLMILLVISTQITVLPVIFTHSVIKLS
                     GISDFKIHSYIIKTSEYPEEFFSNAVWGKKNIKPGEYYSVQAVSMFTTNQFILLCPKD
                     IIRFYRESWKFDLLNVDFDTNTRKKLQEEAAYCVPISAISVKRWDMPLQGSKPSN"
     gene            6691..6879
                     /locus_tag="LSX49_004502"
     CDS             6691..6879
                     /locus_tag="LSX49_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001309252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HBL7170809.1"
                     /translation="MASDTFSCRRRLSAGFFSVSACSWHYPNSPKNGKPALSPRHDWL
                     NTGSLLQNIPLRIWFYPQ"
     gene            7000..7740
                     /locus_tag="LSX49_004503"
     CDS             7000..7740
                     /locus_tag="LSX49_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL7170810.1"
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAY
                     LLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLNGVRPFVRILSEK
                     VRARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAV
                     RRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFAL
                     DMAATLAVPFTGDGRDAAEILRTLPPLR"
     gene            complement(8025..9002)
                     /locus_tag="LSX49_004504"
     CDS             complement(8025..9002)
                     /locus_tag="LSX49_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL7170811.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNT
                     LSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVE
                     LPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
                     YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPA
                     PISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPR
                     LKAPNDESKENPLQPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     gene            9748..10071
                     /locus_tag="LSX49_004505"
                     /pseudo
     CDS             9748..10071
                     /locus_tag="LSX49_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10073..10177
                     /locus_tag="LSX49_004506"
                     /pseudo
     CDS             10073..10177
                     /locus_tag="LSX49_004506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            10238..10751
                     /locus_tag="LSX49_004507"
                     /pseudo
     CDS             10238..10751
                     /locus_tag="LSX49_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566943.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
BASE COUNT         3030 a         2443 c         2447 g         2993 t
ORIGIN      
        1 atttcagggc agggaatagt attgttaatt tcgggagaaa cttaaagttg ccacatcgac
       61 agtttcatca cacaggcttt tgtcctgaaa acttttctta ttttggactt tcgccagcca
      121 ctgtccaata tgaagagaag gtactgtgac gataccatcc tcattagtta caaaggtgag
      181 ttctgcttta tgaacaggat gtttgtgctc aactgcatga gtatgacggg atgatttcag
      241 ataactgacc gagtcaagct ccatgatagc tccggcgagc ggggacgttt tatacaggac
      301 tttcagcttc acatcttcac tgaaacgact tatatcggat aacggaatga tttcaagctc
      361 atgccccgtt ggagactgat agagttgtgc tggcatctgc tgttcaccag gaataaaaga
      421 tttcgcatat ttagtgacaa actcacagta agccacatca tttctgccct cccggctgac
      481 cggtttccat cctgaagagg ttctcgacca gtatcccggt ttcatatatg ttgacaaaac
      541 gtagccatta tctttgcttg cagactcagt tttatagaca taatccgtgg acgctggctt
      601 cagtgttatt gtctctttcc cgttataaat ccggggattt tcaaagaaat tccttctgtc
      661 aggaattgtg ccctttgagg ggaaattatg accataacca atctctgcgg taatgttgtt
      721 ctctgcctgt ttacctgtaa tccagacatc gtgggccagg acatgccccg atgctgtcag
      781 acaaagagct aagatataac ctgtattttt catcatgatt tgttaccact gataacgggt
      841 ataaagactg acagttctgc ctgaaagcgg cactcctttg ccattcatgg caagcttgtt
      901 gaaggcatta tccagagcca ctgatgcctc aaagccttta acacttacag gcttataaga
      961 cagtgaaaag gaatgtacgg catagccagc ctgatgggga tcgccttttt tcacatgcgt
     1021 ggctgctgcc gaaagttcag cacgccatcc ggcagaaact cctccatgac caacaggtat
     1081 acttatgtca ctgatgagtg tgtcaggatt gccggagccc agccattccc tgctgctggc
     1141 atccatactt tccgtgcggt tataagaaag catccagtca aaataatcag actggtaatt
     1201 tccctgcata tcccatcccc agatacgggc ccgggataca ttataagaat aagaacgcat
     1261 ccgtttcata tccacgcgcg tggcaatata gtttctggca tccgttccga aatatccgcc
     1321 tttcaactgc agccgatcat tgcctgtaag caggccgtcc agttgaatac ctgcgccaat
     1381 ctcacgggta atgttatttt ctggtttcag attaaggtta ggtacccagt aattgggttt
     1441 acccttgcgg taaaaatgta catcatccct gtacatttct gccattgtgg gggcacggaa
     1501 tgcagaggat atggagccgt acatcatcag ccagtctgtc ggtgagactg aaatcgccgc
     1561 ccttggggac aggcgttcgg ctttcagttc tccggcacgg ggattgaagc tcttgtaccg
     1621 gtcatagcgg gaaccgacga taatgttaac cgggtagctt ttcattgtca tttcatcctg
     1681 gaaatacaac gatgtaaagt caatgtttcc ttccggatat agtgtggcag agccttctgg
     1741 cttctgctgc tgacggtaat attcagcgcc ataacttaac tgatgggctc ccggaaaaat
     1801 cagagtatga ctcctgttga caacattaac accggaggtt ctgttgtttc tccattctgc
     1861 cgttttgttg tgaccgtttg tcttgatagt gatatcactg agatataaag ttgactttac
     1921 attgatgagg ctgttatcca caggagcgta ctggtaccag aactgtacgt cattttgtac
     1981 tgtttttctg tcacgcaggc cgctgtcacc atgtgtctga gtgggattgc ccggttcagt
     2041 ggtgttattc cggtagagac gcaagctggc acctgctttg ttactgtctg ttataccgac
     2101 agagcctttc gcaaacaggg ctgcaggttt ttccttgtta ggtgcgcgct caccatcact
     2161 ttgatagata ttacctcttt tacgcataat gacagaaagg agcgcatctg tttttccggt
     2221 tttaccgaac caggtgagcc ccgagcctgt gctgtggtca ccactggcga tatttcccca
     2281 cagacttaaa ccgtttgtct ctccgggggg aaggaaatct gctgcatcgg cagttctgaa
     2341 gtccacaaca cctcccagcc cgccactgcc gtacagactg gagtttggtc cgcggacaac
     2401 ttcgatacgt ttgacgagtg ccggatccag ataagtgcca ctgctttttg ccatgtcact
     2461 gagttgacgg atgccgtcaa caagaacaag taccccgctt ttgtcatagc cgcgtagatt
     2521 aaaggtctgc ccattggtcc gtcctgcacc agtctggctg agaccggcaa cacctttcag
     2581 catgccggct gatgtgaccg cattctgact ccatggcgtg tcattcgtga cgacactgac
     2641 cattgacggc gtttcaaata ccgtgttctg atttcctgtc gcgacaacgg tgattgtatc
     2701 tttagccata gaagaatgac tggtctctgc ctgtaaccct atcgggagta tgattaatgt
     2761 acaaatgacg tttctgatta cgttcatata catgcgaaaa tatatgttaa tattgatatg
     2821 ttataacata tcattttatt aatgcaaccc tgatcacgca gcgttcagtg ataaccagtg
     2881 aatagcgact ctaatacccg gtcgctctgc aatgtatcag cgcctgcgac cgatgctatg
     2941 gatattgatt tttctaccga taaagaacca gcaatacgga atttagactg gccccctgaa
     3001 tctccagaca accaatatca cttaaataag tgatagtctt aatactagtt tttagactag
     3061 tcattggaga acagatgatt gatgtcttag gaccggagaa acgcagacgg cgtactacac
     3121 aggaaaagat cgctattgtt cagcagagct ttgaaccggg aatgacggtc tcccttgttg
     3181 cccggcaaca cggtgtggca gccagccagt tatttctctg gcgcaagcaa taccaggagg
     3241 gaagtcttac tgctgtggcc gcaggagaac aggtcgttcc tgcctctgaa cttgctgctg
     3301 ccatgaagca gattaaagaa ctccagcgcc tgctcggcaa aaaaacgatg gaaaatgaac
     3361 tccttaaaga agccgttgaa tatgggcgtg caaaaaagtg gatagcgcac gcgcccttat
     3421 tgcccgggga tggggagtaa gcttagtcag ccgttgtctc cgggtgtcgc gtgcgcagtt
     3481 gcacgtcatt ctcagacgaa ccgatgactg gaaatatagg ggcaaatcca catccttact
     3541 tttccgtaag gattttagcg ggtcaaaaca gcgttccatg ccggactgat gatctacata
     3601 cttagagtca cataccaaag taaaactatg gatgtatgca agcctgcatc gtcaggaggt
     3661 taaatttcag acctgccagt taccgcgtaa atggcttgat atatgactaa tttatttgca
     3721 caggattttt acgacaacgc tctgaaccag cagttgacgg gatatatagt tgagctcatt
     3781 acagataaag cttttctgta tctctggcgg tggtcataga ccagtaatcg ttattggttg
     3841 ttctatatta tcccgtatga cggtacaacg tttttaacaa ctggcgctgt cacaacataa
     3901 gccaccccaa aatattatat gagtaacaat agtctatata ggagcgtaaa ttacctacta
     3961 tcaaatactt actccaatag catttctgtc tattctattt caattcttta atagaaaaat
     4021 aaggttagat aatatatgac tccctccccc tatccaagaa ataactttaa tacagagcta
     4081 attcaatcat gtatgaatgg agaacacttt tcacttttaa ttgaaatatc accaatcaga
     4141 agtaaaaaaa acatcatggc tcttaaggag tatttggttg atggttattc aaagcaagaa
     4201 agttgtgaaa ggaacaatgt ttccattagt tatttttgcc tatgcctaaa aaaactaaac
     4261 tatacacaca gtattgttag tgctcttaaa tatttctacc gtgagtaaac tgtaactgaa
     4321 gtcttgattc ttacgcttag acactgctaa gccgttatgg catagctgat aatttatatt
     4381 gcactatgtc agctactgta agataatata agctatttta aagaaaactc tgtcattcat
     4441 cattttgttt aatgataggt tttgttatta atataaaaga acatgctcat tcattaaaat
     4501 aaaaacaaga tgttctttta ttattttcat tccctacggg gttagtcctt gattcatttt
     4561 cagtatcttc taactcattc atttgccgat tactttaatt cacagtcttg ttttttatcc
     4621 tgcctattgg agataaaagt ggtatcgatg gatgccgagt gtgttgcaca tgcagtattc
     4681 tcaggaataa gaactgtcac ttccaaaaca cgcgatatat gattgaatct ctgtgggggg
     4741 ataaaaactt gcctttttcc gcagtctgaa aacaggatgg gggcgacgga tggttacgca
     4801 ggcaagggcg aggttcggaa ataaatcaga gattatattc tgaattatta caatagcacc
     4861 agacctcacc attacaacgg tagtttgacg ctggagggat cagaaaacag ataccgtttt
     4921 tactgtaaac ggtggtcata tatggactct cctggtgata taagtactgg ttcgaaacgg
     4981 tttacgacta tatatccggc gtcatcagta ggttcaatga accgcgcaat aatgttatcc
     5041 gagccctgtt tcctaatcac tacgccggta tttgattagc caagtcaagt tcatcttgcc
     5101 atcactattt ttccataccg cattactatc taatacagtc gcacgagcgg ccttctaatt
     5161 tgagggtttc gagccctgaa gaggcatatc ccatcgtttt acagatattg cagaaattgg
     5221 tacgcaatat gctgcttctt cctggagttt cttcctggta tttgtatcga agtctacatt
     5281 aagcaggtcg aacttccagc tttcccgata aaaccttata atatccttgg gacaaaggag
     5341 aataaactgg tttgtcgtaa acatagaaac agcctgcaca gagtaatatt cccccggttt
     5401 tatatttttt ttaccccata ctgcattgga aaaaaactcc tccggatatt cacttgtttt
     5461 aataatgtag ctatgtattt tgaagtcact tatacctgag agcttaataa ctgaatgggt
     5521 aaaaattact ggtaatacgg ttatttgagt cgatataact aataatatca tcaaggatgc
     5581 gacaaatgca gaactaattc ttttagaaag tttatgctgt ggattcattt ttagataaat
     5641 gaggccggga agtattgtca gaataaaaat aaaatatgac atgaaagcca gttcagctat
     5701 cactttgaaa ttaatactct tatctgaagt ttcaatattc ctaaaaacca tctccagtgg
     5761 aattacctga agatgcacca gtaaagcaat agacaacgga atgataagat agatctgaac
     5821 acgtctcaac agtttcattc tattattttt aaacgataag tcatattcaa gatacctcgt
     5881 gtttattatg gctgaaataa caactattag tactcctata cttaaaatag ataaccagcc
     5941 agagttatct ttaacactct ggtcaaaatc aaatgcacag tataacacgt atataaaggc
     6001 catggggaag aggccagata acatcattac agataaaaaa ttaccctgaa tcttattgta
     6061 agcaggaaga ttttttatat cataaggaat aactattggt ataaaaaaag atgttataaa
     6121 aaaaataaaa atgatcataa tcaatgatag aatagttgta caacaaacca ataccaagat
     6181 gcttttaata ttcatcacat caaagaaaat atcaagtcga tccagacgac tgaaatatcc
     6241 ccagagaact atcaacgcaa tccctgatat aatacttgat ggtgttaata ctgaaactat
     6301 tagcgtcttc cacttctgat tcattttaac ttcctggttt tgctataaag agagcataaa
     6361 aaagagtgaa taagttatta cacttcattg tttgactcct cgcagtaacc tttcaggaag
     6421 gttgtcggat atttttgata aattatgtca taaacatatt attgtaagta atgatttcac
     6481 taaatttatt tgatcgtcgt cataatattt ttaatctgaa tatagaagat gattgtgtca
     6541 tatgcagtat gatataaaac gttaaaagtg actgaataga taacagttca tgcatgaaca
     6601 agaccataac ataacataat aaaatatgct tattatgcat aaccttatgt tgtgactaag
     6661 ccgccttaaa actgagaagt agctaagaat atggcgtcag acaccttcag ttgtcgtaga
     6721 aggttatctg caggattttt ctccgtatct gcctgttcct ggcattaccc caattctccc
     6781 aaaaacggca aaccagccct cagcccgcgc cacgactggc ttaatacggg atccctgctg
     6841 caaaacatac ctttacgtat ttggttttac ccgcaataat gcgtgataag caaacaaaag
     6901 gatccgcgcg ctgcgattta ttgtcgtgga aggatccggg cgttcaggtc agaatacctg
     6961 tatccataaa cagtgcgtgt gctacgtgaa aaataactca tgaacaatgt cattcccctg
     7021 cagaattcac cagaacgcgt ctccctgtta cccattgcgc cgggggtgga ttttgcaaca
     7081 gcgctctccc tgagaagaat ggccacttcc acgggggcca caccggccta cctgctggcc
     7141 ccggaagtga gtgcccttct cttctatatg ccggatcagc gtcaccatat gctgttcgcc
     7201 accctctgga ataccggaat gcgtattggc gaagcccgga tgctgacgcc ggaatcattt
     7261 gacctgaatg gagtaagacc gtttgtgcgg atcctgtccg aaaaagtgcg tgcgcgacgc
     7321 ggacgcccgc caaaagatga agtgcgactg gtgccgctga cagatataag ctatgtcagg
     7381 cagatggaaa gctggatgat caccacccgg ccccgtcgtc gtgaaccatt atgggccgtg
     7441 accgacgaaa ccatgcgcaa ctggctgaag caggctgtca gacgggccga agctgacggg
     7501 gtacactttt cgattccggt cacaccacac accttccggc acagctatat catgcacatg
     7561 ctctatcacc gccagccccg gaaagtcatc caggcactgg ctggtcacag ggatccacgt
     7621 tcgatggagg tttataccag agtgtttgca ctggatatgg ctgccacgct ggcagtgcct
     7681 ttcacaggtg acgggcggga tgctgcggag atcctgcgta cactgcctcc cctgaggtga
     7741 cggcatacgc gcttccttat ataagctgtg gtcagcagaa cagacataac ataagctgga
     7801 gcatgtatat aagctgtagt gagtaagtca tgttttatga agggagcaat gcctcagcat
     7861 caggttacgg gatcacttac gtaagggaca ggcagatggc agctcagcta cagacagcac
     7921 tgcaggaaac agaatataaa ctgcagtgag cagaccactc actgcaccgg ttaatataag
     7981 ctgtagtcag taaaggagcg ctcttcactg actacagttt atgttcagcg ggatttgaag
     8041 agtttttcca ggtcatccag cgtgatgccc agtttctcaa gcagggcaag cttctccgcc
     8101 atctccggac tgactttttc cgcaggtgaa ggttgcaacg gattttcctt actctcgtca
     8161 ttcggcgctt ttaaccgggg acgccggtag tgaatacaga agaattttgt ccgcccccgc
     8221 tggatctccg tgtaatcaag atatccaatc tcgcgcaact gctccattgc ccgtctgacc
     8281 gtctggttct gggaaaatac aggagacttc agattgaggc gtgcacgcag ccgcgccagc
     8341 gatatcggtg ccggatcccg gggcaggctc tctataaagg tgtagagtgc ctgggcggac
     8401 tcccgtcgct tcagggcatt aatcgcctta agctggagaa ggacttttct gtcaaactgg
     8461 tacagttcaa acaggcgggg atcggcctgt aactgcacaa tatcccgctc agtatcgtag
     8521 taagctgact gtaccagatg ggtgatatat tcccgggtgt gcttctcatc ggtacgggaa
     8581 aacgaaatca cggtaccggc aatgcgcttc agggaagggc tgatgcgctc acgcagcctg
     8641 cgggatgact ggcttgaagg tataccacac agttttgcaa actcaacaaa aggcagttca
     8701 actttgtcac caatcacgtt atggcgggca aaggaatgaa tgatccccac ccaggtcttg
     8761 aaatcattat ccatatccag gcgggggccg gtgatctcaa ccttatcgaa tccctcagca
     8821 cgggccaggg aaagacgtgt cagctcttcc gtggcatcag tacgtgacag tgtatttttt
     8881 ttactgttct tcagtgattt aagggtcggt acaaaaacgc ccagacgcat cagcgccaca
     8941 ggttgtacgg tgttgttatt gtttggtgtc agtgtcacca gctcaccgga ggacttatcc
     9001 acctcgccga acagtttttt gatgtctgaa ttttcgtttt ccagaaagcc tccagcctgt
     9061 ggacagtaaa agaataaaca gaaaatcgtg tgtcagaact ccgctaactg actgaagaaa
     9121 aacctgcagc ctgtatttaa caactgagtc tggcatactg accatagttt atgtcattaa
     9181 cttacttcag tatatggatt actgaataca gcttatcatt agcatgttac agtttatcag
     9241 taacatgcca cagcttatgt gatcgtggtc ccggcccatg agtgacaagg tttgcagcga
     9301 tatggggatc tttaatggat cctttgttga tcattcatgg atctgtttac tggatcgggc
     9361 ctccggatat gtggataaat cattccagaa ggacagcgca cacaaccgtt ttatgaaagg
     9421 gcttcagggc gtacctgctc cctgtaacta cagatacatt gcgcttcctc gccggttcgc
     9481 gggcttcgcc cggtcaccgg tctgcggcga gcactgtttt ttctgatgtc tgtctttaca
     9541 ggtaattttt gacggaatct gccgtacttc ctgagcgtac ggtcatatcc gaagtacact
     9601 tcatatgtgt gtttcaatgc cagggattgt gtatacaaac tacaggtgtc agcgccagtg
     9661 atataagacg gtaattcacc atttggattg tccgctccac ccaacatgtt gtttccttaa
     9721 ggttctcaca ccagaaagga catcaacatg ctgagcagag aggactttta catgataaag
     9781 caaatgcgcc agcagggcgc gtacattgtc gatattgcgg ctcagattgg ttgctctgaa
     9841 cggacggtca gacgctacct caaataccct gaaccgccag ccagaaagac ccgccacaaa
     9901 atggttaagc tgaaaccgtt tatggattac atcgacatgc gcctggcaga gaatgtctgg
     9961 aatagcgagg ttatcttcgc ggagattaag gcaatgggtt atacgggcgg acgttccatg
    10021 ctgcgttact acatccagcc caaacgtaaa atgcgtccgt caaaaagaac aaggagagag
    10081 ttaccggtta aaagagaaac gtaaagctgg agtgctgacc aaaaacacaa cgccaatcag
    10141 tgatgatgaa atggtgcaaa gcggacagca tcagtaacga aagtatttag cgggcatgaa
    10201 aatggcaaat aacggtcaaa catcgtggcg ttgacatagt cgcagttttg gtgaacgaat
    10261 cacagacaaa gatgccatgc accaggctgt tgttcagtat gcagagcggg ccgcagagaa
    10321 actacgtggg gagcgtcagt attgccggca ggtgacgaca tttgtacgga catccccctg
    10381 aaccctgtta cagcaatgcc gctgtggaaa agctttcatt gcccacacag gacagccggg
    10441 acattattgc cgccgcatgc agagccttaa accatgtctg gcgtgaaggg taccgctata
    10501 tgaaggcagg agtcatgctg gctgatttca caccatcggg tatagcgcag ccgggattat
    10561 ttgatgaaat ccagccccgt aaaaacagtg aaaagttaat gaaaacactc gatgaactga
    10621 accagtcggg aaaagggaaa gtgtggtttg cggggcgagg aaccgcccct gaatggcaaa
    10681 tgaaacggga aatgttgagt cagtgttata caactaaatg gcgagatatt cccctggcca
    10741 ggctgggtta gttcagtcat ctccgaacat attttcagcg tttcttctgg tctggtcttc
    10801 accgtcattt ctcgacagac tctgctctgt aaggggagta ctgcaatcca cagacgtatg
    10861 gagaccagat tgtttttcca gtaattcaat caatttcttt tcaaccgaaa aag
//
LOCUS       DAFGPF010000148        10818 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFGPF010000148 DAFGPF010000000
VERSION     DAFGPF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10818
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.148"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..264
                     /locus_tag="LSX49_004508"
     CDS             <1..264
                     /locus_tag="LSX49_004508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HBL7170812.1"
                     /translation="LKSMGLDLELLNTFIAQIFDAKNCRSLLKEINFETGVDGEFFIA
                     GTPYAKIGVNVPADGDGGVKINGGLYISGSPIVSLNVEIGPNG"
     gene            257..1441
                     /locus_tag="LSX49_004509"
     CDS             257..1441
                     /locus_tag="LSX49_004509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7170813.1"
                     /translation="MAENKIYAVLTDRGAQLEAAALASGVPVVLNKFVIGDANGNDDV
                     TPDPARTALIHETYRGDIKSAENSGNQVIFTLYVPPDTGGYTIREVGILTDKGELYSV
                     ARSPDILKPTDSNGALISITYKYTLAVSSTSTVNVVVYDNYVTPEEADKKYLQISKNL
                     SEIPANGETAQQAARKNIGIDGDVAYRDKGNAFTHPNTFKDDVIFEDVLSSKKQININ
                     KPGTDLTLFSFAGLSDVSGDYLDFSTRGENNQKVFYRLRGVHYDGLVLLCGGQTYKYW
                     NEANLKPVKTINGESPDENGNIDISLSPDPSPEIGVVGAVGTYALVAINHAPQILPGS
                     IWAGGDLYYASINNTGSYNTDIATKPFYDTPLIGSWRAMAYSPGGVGDIGTACFLAIR
                     IA"
     gene            1441..1830
                     /locus_tag="LSX49_004510"
     CDS             1441..1830
                     /locus_tag="LSX49_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170814.1"
                     /translation="MISVDSFRKITNPVFNDEHGLSINIICDIDGIGNDIPFTAMKND
                     CEEHGRVLYERALSGDYGSISKFVKKEQTQKLQTTLRTVGDLSIEAFSIQCAVDAGTA
                     SDAQIENLAELKEAIATRIGENREGIK"
     gene            1827..3329
                     /locus_tag="LSX49_004511"
     CDS             1827..3329
                     /locus_tag="LSX49_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBL7170815.1"
                     /translation="MSVTNFLHGIRTLEYDDGTKEINTVDISVIGIVGTAPDSSYPTC
                     ASLLWGSELADNLVEFSTVMPGADGNNWIVEIVDLGINGNVATPGYSTLPDGSRKLTM
                     ITDGAMTPSKMYDQNQQYKEGLQIGEYINVTFGGDHAGTGTVFALPPTNLSGGKDESF
                     KYNVPTLIAGSQKKAGLLGGSGTLPPAVSEILNQEDAIIVVVRVEEDSDETKMRQNVV
                     NGINALLTSAQINQVTPRILIAPDYSANDYIAEQLEVVTNKLRGVGYIDSPRGATPAD
                     VVNRRQRYGGRMEILRPRVYSTSDVSGLSRPYSAIAAGLRARIDNEKGFWWSKSNQNI
                     YGITGLEQVDDFIIGETNCTANLLNASQVSTIIRYDGFRHWGNYLCSLSPQWSFECVR
                     RTADVIEDSIARAMMTDFIDRPIDLHLGTDVVESINAYLHKLEEQGAINGGRAWLDEE
                     LNTKESLAAGNLYINVDFGPKSPAQTITLMYRINNDYTVEALASLFKETV"
     gene            3347..3859
                     /locus_tag="LSX49_004512"
     CDS             3347..3859
                     /locus_tag="LSX49_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HBL7170816.1"
                     /translation="MADSNTYRAFALFVQGERVLNCTEYTPVDMKIIEDDFKTGAMDT
                     AITLDGGMEKMSASFKVSGSDSGVMGYLGLIPGAKTRFEIRSAYTDNYGVNFERIDTY
                     EGLITAITDDAQGTDSKSAVGQSVTIAPSYYKRVQNGKIIYEIHPAKMKRVINGVDVL
                     AGVARILHVY"
     gene            3872..4153
                     /locus_tag="LSX49_004513"
     CDS             3872..4153
                     /locus_tag="LSX49_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HBL7170817.1"
                     /translation="MESLLDSMTITLSRPFIIKGESRDTITIREPKLRDRIMFSNDKS
                     GLEERTATMLARLANLEREDLYALPACDYDQMEAAFNELVKPPKDRHQI"
     gene            4262..5902
                     /locus_tag="LSX49_004514"
     CDS             4262..5902
                     /locus_tag="LSX49_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170818.1"
                     /translation="MAISQNFKTQVVFGGRIDPSFRRGTTELNDAIRQTSSTVGKLTK
                     SQDKLKDKIAAMKLAGKDVSDLSAQYQKLDRRIKATTQDQEALNTQLAKKQRLEKWTG
                     RAKGAAKWGGRAAAGAVRATGRGIKWGTLGAAGLIGGAAAGALAMNAETSEKLGLAKS
                     YGVGVEKYAAWENIGKAAGLNGENIGDLSEELTNKIGEIGNEKSLNPMLFQIGLTKKR
                     MAGWDREKQFNEVMRRISEMKDEKQAASLADQLMGGEANKIMTYMKATGKSWEQTMSD
                     AQKSNLLTKEGAEGAARAHVSVTNLWGSITSGLADTLGKIGGELAPTFDSVRETFTSW
                     FKDNQGGFVSTITEWVKPENMKKMWDGIVNFGEGCVKFGKIIWAVVKKLEWLIPDEKS
                     DEEQKTYNDEYNRAYQEFMDSGGKYSPNAGLTADNIAKAKAEEAVENMRHPERQEQAK
                     SQAESMLAFVNPLSGMVNKNTAPAALDSSTLNIDTLKQAVSTPAPEQNNKIEINIVGA
                     TDPQSIQQSAASGVLDGLRQAASSYNRGAMFDKPAAAG"
     gene            5938..6327
                     /locus_tag="LSX49_004515"
     CDS             5938..6327
                     /locus_tag="LSX49_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7170819.1"
                     /translation="MLGLGDFIFAISTVAYNKLQRSDAWRWAQQTRFGKNDALQITGR
                     PNPTITIDGKINALFLDGCGVGLLTDLRALGNTGEPQQLVLGTGEVKGYWVLRELTET
                     QNSFLMGGTPKSQDFSLTLEYYGASLD"
     gene            6489..6713
                     /locus_tag="LSX49_004516"
     CDS             6489..6713
                     /locus_tag="LSX49_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HBL7170820.1"
                     /translation="MGPQMITYTTRDGDRLDQICLAVYGRASKTTETVLYQVSNYGVT
                     DMCAVFRAGEKIVLPDIEPEPVKKETQLWD"
     gene            6717..7761
                     /locus_tag="LSX49_004517"
                     /pseudo
     CDS             6717..7761
                     /locus_tag="LSX49_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287093.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="late control protein"
     gene            7928..8347
                     /locus_tag="LSX49_004518"
     CDS             7928..8347
                     /locus_tag="LSX49_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170821.1"
                     /translation="MVVKNGLACGIMLALVGCATKPVSNEQATPVPEKQIISTALLEK
                     RDGTGEVIIKRDSGFFGSACFSRVYVDGKEVADLGTAQKVVVYPTIGDHVFSAWPKGV
                     CGGGMSEQAGKVTTDRTLMYRIGYGSNGEYGIHPTAF"
     gene            8819..9484
                     /gene="yecA"
                     /locus_tag="LSX49_004519"
     CDS             8819..9484
                     /gene="yecA"
                     /locus_tag="LSX49_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HBL7170822.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPAQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(9535..10746)
                     /gene="tyrP"
                     /locus_tag="LSX49_004520"
     CDS             complement(9535..10746)
                     /gene="tyrP"
                     /locus_tag="LSX49_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HBL7170823.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNIRKLRWVF
                     IIGSAIPLVAYIFWQLATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
BASE COUNT         3196 a         2282 c         2763 g         2577 t
ORIGIN      
        1 ctaaaaagca tggggttaga tttagaacta ttgaatacat ttattgcaca aatatttgat
       61 gcaaaaaatt gtcgttcctt attaaaagaa ataaatttcg aaacgggtgt cgatggtgag
      121 ttttttatag ccggtacacc ttacgcgaaa ataggcgtaa acgtcccagc agacggcgac
      181 ggcggtgtaa aaattaacgg cgggctatat atatcgggct caccaattgt tagtttaaat
      241 gtggagatag ggccaaatgg ctgaaaataa aatttacgca gtactgacag accgtggcgc
      301 acaacttgaa gccgctgcgc tggcatcggg tgtacccgtg gtgctgaata aattcgttat
      361 tggcgacgca aacggaaacg acgacgtaac accggacccg gcacgaactg cattaattca
      421 cgagacgtat cgtggggata ttaaatccgc agaaaatagc ggtaaccagg ttatctttac
      481 actttacgta ccgccagaca ctgggggcta tactatccgt gaggtgggga tattaacaga
      541 taaaggcgag ctgtactctg tggcgcgctc gccggacatt ttaaaaccta cggacagcaa
      601 cggtgcgctg atttcaatca cgtataaata cacactcgcg gtgtccagca catctacggt
      661 taatgttgta gtatatgaca actacgtaac tcccgaggaa gctgacaaaa aatatttgca
      721 gataagtaaa aacttatctg aaattcccgc aaatggtgaa actgctcagc aggctgcgcg
      781 gaaaaatatt ggtatagatg gggacgttgc atatagagat aagggtaatg catttactca
      841 tccaaatact tttaaagatg atgtgatttt tgaagacgtt ttatcctcta aaaaacaaat
      901 aaatataaac aaaccgggca ctgatttgac gttgttttca tttgctggtt tatcagatgt
      961 gtcgggcgat tatttagatt tttcgacccg tggagaaaac aatcagaagg ttttttatag
     1021 attacgcgga gttcactatg atggcctggt gttactgtgc ggcgggcaga cgtataaata
     1081 ctggaatgag gctaatctta aaccggttaa aacgattaac ggggagtcgc cggatgaaaa
     1141 tggcaacata gatataagtc tttcaccgga cccatcaccg gaaataggtg ttgttggcgc
     1201 ggttggtact tatgcgcttg tcgctattaa tcatgcacca caaatactcc cgggctccat
     1261 atgggctgga ggggatttat attacgctag tataaataat accggttcat ataacacgga
     1321 tattgccaca aaaccatttt atgacacacc acttattggc tcatggcgag ccatggcgta
     1381 ttcacccggt ggagtcggtg atattgggac tgcctgtttt ttagctatta ggattgcgta
     1441 atgataagcg ttgattcatt tagaaaaata acaaaccctg tttttaatga cgagcatggg
     1501 ttatctataa atattatttg cgatattgac gggattggaa acgacattcc attcaccgca
     1561 atgaaaaatg attgcgagga acacggtagg gttttatatg aaagagcgct gagcggggat
     1621 tatgggagca tttctaaatt tgtaaaaaaa gagcagacgc aaaaactcca gactacatta
     1681 cggactgttg gcgatctgtc aattgaggca ttctcaattc agtgtgcagt agatgccgga
     1741 accgcatctg acgcgcaaat cgaaaatttg gccgagctta aagaagcaat agcgacgcga
     1801 attggtgaaa atagagaagg aataaaatga gcgtaactaa ttttttacac ggtattcgca
     1861 cgctcgaata cgacgacggc acaaaagaga tcaacacagt agatatttcc gtgattggga
     1921 ttgttggtac tgctcccgat tccagctacc caacttgtgc atcactatta tggggatcag
     1981 agctcgcaga caatcttgtt gagttttcga ctgtcatgcc aggggccgac ggaaacaact
     2041 ggattgttga aattgttgat ttgggaatta acgggaatgt agcaactcca ggatacagca
     2101 cactgcccga cggttcgaga aaattaacaa tgatcacgga cggtgccatg accccgtcaa
     2161 aaatgtacga tcagaaccag cagtataaag aaggactcca gattggagaa tatattaacg
     2221 tcacattcgg tggtgatcac gcaggaacgg ggactgtatt cgcgctcccc ccaacaaatt
     2281 tatccggtgg taaagacgaa tcgttcaaat ataatgttcc gacgttaatt gcaggcagtc
     2341 aaaaaaaagc tggattgctc ggtgggtctg gaacccttcc tcccgctgta tctgaaatac
     2401 taaatcagga ggatgccatt attgttgttg tccgcgtcga agaggacagc gacgaaacaa
     2461 aaatgcggca gaacgtcgtt aacgggatta acgcattgtt gacgtctgcg caaataaatc
     2521 aagtaacgcc gagaatttta atcgctccag attatagtgc taacgattat attgcagaac
     2581 aacttgaagt ggtgacaaat aaattacgag gcgttggata tatcgattca ccgcgaggcg
     2641 ctacgcctgc tgacgttgta aatcgtcgtc agaggtacgg cggcagaatg gaaattctgc
     2701 gccctcgtgt ttattctacg agtgatgtta gtggtttatc tcgtccgtat tcagctatcg
     2761 ctgctggttt acgagccaga attgataacg aaaaagggtt ttggtggagc aaatcgaatc
     2821 aaaatatcta cggaattaca ggactcgaac aagtcgatga ttttataatc ggtgaaacga
     2881 actgcacagc aaatctgctg aacgccagcc aggtcagcac aattattcgc tatgatggat
     2941 tcagacactg gggtaactat ctgtgtagcc tcagtcccca atggtccttt gaatgcgttc
     3001 gtcggacagc tgacgtaatt gaggattcaa tagcccgggc aatgatgacc gattttattg
     3061 atcgcccgat agacctgcac ctcggaacag acgttgtaga gtcgataaac gcgtatctgc
     3121 ataaattaga ggagcagggc gcgattaacg gaggacgggc gtggttagat gaagagttaa
     3181 atacaaaaga aagtctggcc gctggtaatc tttatattaa tgttgacttt ggaccgaaat
     3241 ccccggcaca aacaattacg ttaatgtacc gcattaataa tgattacaca gttgaagctc
     3301 tggcctctct ttttaaagaa acagtctaat aatctggaga attgatatgg cagatagtaa
     3361 cacctatcgt gcatttgcgt tgttcgtcca gggagaacga gttttaaatt gcactgaata
     3421 cactcccgtc gatatgaaaa taatcgaaga tgattttaag acgggcgcta tggatacagc
     3481 tatcactctg gacgggggaa tggagaaaat gtcagccagt tttaaagtct ctggctccga
     3541 ttctggtgtg atggggtatt tgggattaat accaggtgct aaaacaaggt tcgaaattcg
     3601 aagtgcatat actgacaatt acggtgtcaa ttttgaacgt attgatacat atgaggggct
     3661 tattacggcg attactgatg acgcgcaggg gactgattca aaatcagcag ttgggcaatc
     3721 agtaacgatt gcgccgagct attataaacg agttcaaaat ggaaaaatta tttacgagat
     3781 tcatcctgca aaaatgaaac gagtaattaa tggtgttgac gttcttgcgg gcgttgctcg
     3841 tattctccat gtatattaaa aggcaaataa aatggaatca ttattagaca gtatgactat
     3901 tacgctctct cgcccgttta ttattaaggg ggagagccgc gatacaatta ctattcgcga
     3961 accaaaatta cgcgaccgca ttatgttcag taacgataaa agtggtcttg aagagcggac
     4021 agcgacaatg ctggcgcgcc tggcaaatct ggagcgtgag gatttatatg cactgcctgc
     4081 gtgcgattac gatcaaatgg aggccgcatt taacgaactg gtaaagcctc cgaaagaccg
     4141 acatcagata tagttattct gattccgttt attgcgaaaa aacttgccat cccgcccgat
     4201 acgcaaatgg acctgccgta ccgggttttt aatttctatg taaacgaggt catgaaaatc
     4261 gatggctatt tctcaaaact ttaaaacgca ggttgtattc ggtgggcgaa tagacccgtc
     4321 gtttcgtcgc ggtacaacag aactcaatga tgcgattcgg cagacgtcgt ctactgtcgg
     4381 gaaattaacg aaaagtcagg ataaattaaa agacaaaatc gcagcaatga aactggcagg
     4441 taaagacgtt tctgatttat ctgctcagta tcaaaagctg gaccgtcgaa taaaagcgac
     4501 aacgcaggac caggaggcgc tgaatactca acttgctaaa aaacagcggc tggagaagtg
     4561 gacgggtcgc gcaaaaggag ctgcaaaatg gggcggacga gccgccgcag gtgcggtgag
     4621 ggctacgggg cggggtatca aatgggggac acttggcgcg gcagggctca ttggcggtgc
     4681 tgcagctggt gcgctggcaa tgaatgcaga gacgtcagaa aaactcggtc tggcgaagtc
     4741 ctacggcgtt ggcgtcgaaa aatacgctgc gtgggaaaat attggtaaag ccgcgggcct
     4801 gaacggcgaa aatatcgggg atttgtctga agaacttaca aataaaatcg gcgaaatcgg
     4861 aaacgaaaaa agcctgaatc ccatgttatt tcaaattggc ctgacgaaaa aacgaatggc
     4921 tggctgggat cgggaaaaac agtttaatga ggttatgcgt cgcatctctg aaatgaaaga
     4981 tgagaagcaa gcggcgagcc tcgctgacca gctcatgggg ggcgaggcta ataagatcat
     5041 gacgtatatg aaggcgacgg gtaaaagctg ggaacagaca atgtctgacg cgcaaaagtc
     5101 gaatttgtta acaaaagagg gtgcggaagg ggcggcgcgt gcgcatgtat cagtgacaaa
     5161 tctgtggggc tctattacgt cgggacttgc agatacactc ggtaaaatcg ggggggaact
     5221 cgcgccgacg tttgactcag tacgtgaaac atttacatcc tggtttaagg ataatcaggg
     5281 tggttttgtc agcacaatta ctgagtgggt aaaaccagaa aatatgaaaa aaatgtggga
     5341 tggcatcgtc aattttggag aaggttgcgt caaattcggg aagattatat gggctgtcgt
     5401 aaagaaactg gagtggctta ttccggatga aaaatcagat gaagaacaga aaacttataa
     5461 tgacgaatat aatcgggcat atcaagagtt tatggattcg ggaggtaaat attcaccgaa
     5521 cgctggattg actgctgata atattgcgaa ggcaaaagcc gaagaggctg tcgaaaatat
     5581 gcggcatcca gaacggcaag aacaggcaaa atctcaggca gaatcaatgc tcgcgtttgt
     5641 taatccatta tccgggatgg taaataaaaa taccgcgcct gcagcactgg attcgtcgac
     5701 gttaaatatt gatacgttga agcaggcagt ctcgacacct gcgccggagc aaaacaataa
     5761 aatcgaaatc aatattgtcg gtgcgacaga tccgcagtca atacaacaat ctgcagcgtc
     5821 gggggtgctc gatggactga gacaggctgc gagttcgtac aatcgtggcg cgatgtttga
     5881 taaaccagct gcggcggggt gacaatgagt gatgcaataa acggtgctga ggatatcatg
     5941 ctcggcctgg gtgatttcat ttttgctata tcaacagtag cgtacaacaa actgcaacgt
     6001 agtgacgcct ggcgctgggc tcagcaaaca cgattcggga aaaacgacgc gttgcagata
     6061 accggacgac cgaaccccac aattactatc gatggaaaga taaacgcttt atttcttgac
     6121 gggtgcggcg tcggcctgtt gacagatttg cgagcgctcg ggaacacggg agaaccccag
     6181 cagctagtgc tggggaccgg ggaggtgaaa gggtactggg tgctgcgaga actaactgaa
     6241 acgcaaaaca gctttttgat gggcggaaca cctaaatcgc aggacttttc actcacgctc
     6301 gaatattatg gagcttcgct agattaatac aaaatcaagc gctaccagag cacttaacaa
     6361 gtataaaaat aataaaaaaa actacgaaca taaatgtaaa acaacctgat ggtatttttt
     6421 ttgacgccga aatactaata cctctccgac tactaaaatt aattctcatt atgaaatcct
     6481 tttaattaat ggggccccaa atgattacat acactacacg ggacggtgac cgtctcgatc
     6541 agatctgcct tgcggtctac gggagagcgt caaaaacgac agagactgtt ttatatcagg
     6601 tttcgaatta cggcgtaacg gatatgtgtg ccgtgtttcg tgctggagaa aaaattgttt
     6661 taccagatat cgaaccagag ccggttaaaa aagaaacgca attatgggat tgatgaatga
     6721 gtgattacgt aaatactggc gtggaggcgt ggaaacctaa tttttatata tctgctgata
     6781 ataaaaacat cacggataaa ataagaaaag gtttgatcaa tatcacgctg acagattacg
     6841 gcggctccag taaacagaca gacgaactcc gcgtagcaat agtttctgaa actctgaaaa
     6901 ttccggcccg cggagtaaaa atcagtattg ggctcggttt cggtaatcag ataattgata
     6961 aagggatata catcgttgac ggtgctagca gtggcggtga accccgggta gttgatttca
     7021 cagcaaaagc ggctccgatg aacgcagcaa aaggatctcc gacagttcag agcaaaaaga
     7081 ctcgttcctg gagcgacgtc actgtcagcg atatcgttgc gacaatagcg agcgataatg
     7141 ggctaaaacc acgcgtatca aagcggtttg cagacaatgt tatcacgcaa ctcgatcagg
     7201 tcggcgagtc agatatgcac ctgatgtcgc ggctcgcaac gagattcgat gcggtgagta
     7261 aacccgcggg cgggtactgg atattcctgc cgcgcggcgc gggcgaatct gttagcggtg
     7321 ctccgctcca gcactacacg ctaactcgtc gtgataactc cagctggggc tattcgagaa
     7381 atggacaaag tggcgatagt ggtagcggtg gcgaaaatcc ggaaccgacg tatctgatta
     7441 aatatcacga cacagcaact gggcagatca aagaattgcg gacaaggtag tggcggcgat
     7501 cctgtcattg aatggccggc agttgagccg tcgctcgacg cagcgaaaga agctgcacca
     7561 gggctcaagg gcggtgcagc taaaaaagag ttctctatga cgtacacgac gccagcgacg
     7621 ctcgatttag tgtcgctgac agcagaatgc aaagtcacaa ctcaaggttt cgggaccgag
     7681 gaggaccggg actggactat caacacactg agtctgacgc tcgctgaaaa cggtttttcg
     7741 gttcggctgt ctctggagta aatgggctcg gcgagccggt ggcggtatga atttagtatt
     7801 aacagatgtc gactgcaaac ggcacctgcg atatttttag gcgtaagccg gagaacgaag
     7861 agtctctggt gctgaacgtt gttatcgtta gatgctgaca tatttttaat attgggagtt
     7921 ttcaaacatg gtcgttaaaa atggtcttgc ctgtgggatt atgcttgctc ttgtcggttg
     7981 tgctacaaaa cctgtctcaa atgaacaagc cactcctgtt cctgaaaaac aaattatcag
     8041 taccgcgtta ctcgaaaaac gagacggtac gggagaggtg atcatcaagc gtgactcggg
     8101 tttctttgga agcgcgtgtt tttcccgtgt ttatgttgat ggtaaagagg tggcagattt
     8161 aggtacagct cagaaagtcg ttgtataccc aacgattggt gatcatgtct tcagcgcgtg
     8221 gccaaaagga gtatgtggtg gtggcatgag cgaacaagcg ggcaaggtga caacagatcg
     8281 tactttgatg tatcgcatag ggtatggatc aaacggtgaa tatggaattc acccaaccgc
     8341 gttttaattt gtgttggggt atgtgagttt ttctcatacc cctttacctc gctttgctcc
     8401 tgacagtttg gtcacataaa ggcgcagaac atcaccattt ttgccaaaaa ccttcagaag
     8461 acgatgagta agacgcgtcg taactatatg attatttgat attcatacac accattatgt
     8521 ccggataatt tgccataatt atttgaattt attgcacaaa gcgaccaatt taaaatccct
     8581 cggcgttcgc gctgtgcggg ttcaagtccc gctccgggta ccatgggaaa gataagaata
     8641 aaatcaaagc aataagcagt gtcgtgaaac caccttcggg tggttttttt gtgcctgcaa
     8701 cttgtcgtta caccctcctt aatttttaat caccggcaaa gccactcaaa aagtatctct
     8761 gatacggacc ggcatgtaag ataggtgctg gcgagttgag atccacaagg aaaagcgtat
     8821 gaaaacggga ccgttaaacg aaagtgagtt ggaatggctg gacgatattc tgaccaaata
     8881 caacactgac cacgccattc ttgatgtggc ggagctggac ggtttattga cggcggtgtt
     8941 gagttctccg caagagattg aaccggcaca gtggctggtt gccgtgtggg gtggggctga
     9001 ctatgtgccg cgctgggcgt cagagaaaga gatgacgcgc tttatgaacc tggcttttca
     9061 acatatggcc gataccgcag agcgtctgaa cgaatttccg gagcagtttg agccattatt
     9121 cggcttgcga gaagtcgatg gcagcgagct gacgattgtt gaggagtggt gctttggcta
     9181 tatgcggggc gtggcacttt ctgactggtc aacgttgccc gattcgttaa aaccagcgct
     9241 ggaggcgatt gcgctgcacg gtactgagga aaacttcgag cgggtagaga agatgtcgcc
     9301 agaagcgttt gaagagagcg tagatgccat tcgactggcg gcgcttgatc tacatgcgta
     9361 ctggatggcg catccgcagg aaaaagctgt tcagcaaccg atcaaagcag aagagaaacc
     9421 ggggcgtaat gatccttgcc cgtgcggtag tggtaagaaa tttaagcagt gctgcctgca
     9481 ttaagaggtc aaattgggtg tcagcgttaa ttctggcacc caataagaat ctaatcaccc
     9541 cacttctggt aacaagcctg ccgcaatcaa aaattgcacg ccaatcacag caataccaca
     9601 gagaaacacc accaccagcg ccggacgacc acctttcacc cggtaacccg cctgaggatt
     9661 gtgcttcctg ctttgccagg tcaacagcga agggataatc aatgccagta ccgccagtgc
     9721 cacaccggcg taacccagcg ccatcacaaa tcctcgtgga taaaacagtg caaacgccag
     9781 tggcggcaga aaggtaattg caccagtttg caatcgtcca ccaacggtat ttgaacgctg
     9841 aaacaaatct gccagataat caaataagcc taacgctacg ccgaggaagg acgtggcgag
     9901 ggctaaatca gcaaataaat gcactgccag ctcaacatgc ggagaggcca ccatttcgcg
     9961 taacgcctgt aacagcccgt ttaatccggc atgattagcc agcaatccca taaaggttgt
    10021 tgaatcaatg ctgccaaggg tcgccagctg ccagaaaata tatgccacca gggggatcgc
    10081 actaccgatt ataaacaccc agcgtagctt acgaatgttg ccatccatat agctgacaat
    10141 actcggcacg ctaccgtgaa aaccaaacga cgtaaaaatc accgggattg cagacagtgc
    10201 cagtccctgt tgcaacggca gggttaaaag attcactttg tgaatatgcg gtagcagcaa
    10261 taccagcatc accaccagaa aaataatttt ggcgctgaac agaaaacggt taaataaatc
    10321 gaccagcgaa gttccgacac aaaccacgcc accggcaaca aaagtgaaca acagcacgcc
    10381 agcggttgcc gacattgaaa tacctgtcca gtcgctgatg ctggaggcca acaattcacc
    10441 ggcaccgctg atgtatgccg cagtcagagc atacattaag aacatcatac tgaagcccgt
    10501 cagccactga ccgtagcgtc ccagatagcg ttttgccagc gtgcccagac cggtatctgc
    10561 cgggacatgc tgatacacct ccagcagtaa tagcgccgtg tagcacatca acgcccaaag
    10621 cccaatcaac aagattaacg tgacgctaaa accaacacct gccgcagcca gcggcattgc
    10681 cagcatgcct gcgccaattg tggttcccgc cacgataaaa acacttccca gagttctgtt
    10741 tttcacgctt tcttctgtcc tgacgatctt tatgagtgat atctgcggcg caggttaagg
    10801 cataacggct gattcgtc
//
LOCUS       DAFGPF010000149        10784 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFGPF010000149 DAFGPF010000000
VERSION     DAFGPF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10784
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.149"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            855..1175
                     /locus_tag="LSX49_004521"
     CDS             855..1175
                     /locus_tag="LSX49_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170824.1"
                     /translation="MEARTIPVTLFIHYATSTFSHEKLLVATVDMSKNFPDRYILLES
                     REIEITVNQPEPIDIIGLQVEQLREQKQKTVADAQQRIAAIDDKIQQLLCIEYTPDTD
                     ELPY"
     gene            1206..3422
                     /locus_tag="LSX49_004522"
     CDS             1206..3422
                     /locus_tag="LSX49_004522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170825.1"
                     /translation="MTIFNGLLEAKKGALKNGAIPALAIAIAAPNKKVAENIIIGKLW
                     EAYPDHGDNYFKPKIWEDAPGQPRPGVGEFDETFATEHSFDGEKWVVNTPVDSDCSSA
                     DISQVSDLMKLPARERFAAVLLFSHDANEVDSELLVQTREYLEMLDNSDTDSEDEVDA
                     FNRIVLDAMVACKPIEYMHIAGLNNLVHAILASCDTQEQNPTSWTISKFIKKWVENPG
                     KRDEMLPEVKPETASARPYKQTHATLDREIACALLPVAPEKITPSILKAADEIISQDR
                     EDFKRWSMALRTTDQILAYDRASVFGVIQSAPAKDTYHFPQSLRSHIDNWLQANGQRD
                     ANAVEEKPKEAAPKDDVKVTNHGGGRFSIDGMMSETPSNQGEKSEAANAGERSLQQLR
                     EQFVTPRHVYDVPENNAVSQREPAAITLAEETPPQEQLSEQVKDLVQNVDALVERIHA
                     EEHKRQNAISAIETELKDSDDTDNLALWKNVFKTDERFTSAFSQNGGGTSINGTYIAM
                     KATREFGPFGIGWGVEVLEERFDKGAPIVRKKQVGEKIEWDLIQDGVGGYLCEMHHTM
                     KVRVWYILNGVRGESEAYGCTPYIYDTKYGPTSDGEAPKKSWTDAVKKALSPLGFSAD
                     IFMGLYDNPEYRQRNKAEFDIKNASENAEDATRLRKELDEKLINVANTLAAAVTANEV
                     NKVFGLIAREVDVHRKAAETKGDKEYSSYLGSRLRRITDIKTERLAALTAAQEQTA"
     gene            3419..3988
                     /locus_tag="LSX49_004523"
     CDS             3419..3988
                     /locus_tag="LSX49_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBL7170826.1"
                     /translation="MSTAIAIAKEYASLIDLLETADELTPEMIADTLEGMEGELGDKL
                     DAMMVICRNLQGNANTCAEEMSRLATRKTSFEGKEKAIRKHMLTCLQAAGLDKLKTAK
                     NTFTDAQGAIRVIIDSKDKIPDEYEGVSLVDVETVITPNKRAIKEVIESAEAVAAEIL
                     ARGETPPAELLNPVPGAHLERGERSLRIR"
     gene            3988..4170
                     /locus_tag="LSX49_004524"
     CDS             3988..4170
                     /locus_tag="LSX49_004524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170827.1"
                     /translation="MLKLTLKRGDAVHLVLADGTNGIIEARSRCELGLHLPENIKVTR
                     EKSAFTPQELITPNQK"
     gene            4380..4643
                     /locus_tag="LSX49_004525"
     CDS             4380..4643
                     /locus_tag="LSX49_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4224 domain-containing protein"
                     /protein_id="HBL7170828.1"
                     /translation="MKSDHDIITREEMVELTGSPLKSKQCEALRRAGIFFMERADGHP
                     KTTWGHFMNPIKFRNLQEVTTRKDDEPDFGAIFNGRKEKEPSR"
     gene            4612..5628
                     /locus_tag="LSX49_004526"
     CDS             4612..5628
                     /locus_tag="LSX49_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL7170829.1"
                     /translation="MAGKRKNPADNWMPPRVYQGKAAYEFRNKDNKAIRLCALDAPRS
                     AVWLAYEKAVGDEKERNTFQALTEQFMTSPDFMDLAVETRKDYTKYSGKVLPVFGKID
                     PDKIKPEHIRRYMDQRGLSSRTQANREKSFMSRVFRWGYERGYVQRNPCQGVKQFKEK
                     ARERYITDEEYQAVYEVSPDVVRVAMEIAYLCVARQSDVLSLQKDQLFDSGIYIRQGK
                     TGVKQIKAWSPRLQKAIALARSLPLKTGISSLFVIHQTTGGKYTRDGFNSRWRDVKAA
                     AQEKYPHLQIDFTFHDLKAKGISDLEGSLEEKQAISGHKNPRQTAAYDRKVKVVPVVG
                     GQRK"
     gene            complement(5759..5845)
                     /locus_tag="LSX49_004527"
     tRNA            complement(5759..5845)
                     /locus_tag="LSX49_004527"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5809..5811),aa:Leu,seq:taa)
     gene            complement(5858..5931)
                     /locus_tag="LSX49_004528"
     tRNA            complement(5858..5931)
                     /locus_tag="LSX49_004528"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5897..5899),aa:Cys,seq:gca)
     gene            complement(5985..6060)
                     /locus_tag="LSX49_004529"
     tRNA            complement(5985..6060)
                     /locus_tag="LSX49_004529"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6025..6027),aa:Gly,seq:gcc)
     gene            complement(6212..6760)
                     /gene="pgsA"
                     /locus_tag="LSX49_004530"
     CDS             complement(6212..6760)
                     /gene="pgsA"
                     /locus_tag="LSX49_004530"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBL7170830.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARADLLDQ"
     gene            complement(6817..8649)
                     /gene="uvrC"
                     /locus_tag="LSX49_004531"
     CDS             complement(6817..8649)
                     /gene="uvrC"
                     /locus_tag="LSX49_004531"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBL7170831.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(8646..9302)
                     /gene="uvrY"
                     /locus_tag="LSX49_004532"
     CDS             complement(8646..9302)
                     /gene="uvrY"
                     /locus_tag="LSX49_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HBL7170832.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     ANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            9598..9774
                     /locus_tag="LSX49_004533"
     CDS             9598..9774
                     /locus_tag="LSX49_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170833.1"
                     /translation="MIKIFIGHYINVFYSTVDITLKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            9761..9985
                     /locus_tag="LSX49_004534"
     CDS             9761..9985
                     /locus_tag="LSX49_004534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HBL7170834.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAMGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQAYRQ"
     gene            complement(10053..10775)
                     /gene="sdiA"
                     /locus_tag="LSX49_004535"
     CDS             complement(10053..10775)
                     /gene="sdiA"
                     /locus_tag="LSX49_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HBL7170835.1"
                     /translation="MQDTDFFSWLRTMLLRFQRMEAAEEVYHEIELQAQQLEYDYYSL
                     CVRHPVPFTRPKVAFYTNYPESWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSE
                     AQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRCSTREIPILSDELQLKMQLLVRE
                     SLMALMRLNDEIVMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNM
                     QKKINAPNKTQVACYAAATGLI"
BASE COUNT         3026 a         2704 c         2600 g         2454 t
ORIGIN      
        1 caacaacgct tacccagcgg cagttgttca gaaacacgtt ctgacagccg gaaagacggc
       61 accaaatttt gcgcgtcggc gccaacacgg tgacagaggg aaagacttca ccggcatatg
      121 gcacatgtgt cgaagcggtc tggatggaag cggagcctta acgcgttgtc tccatagcag
      181 gtagccggaa tgtgcaagcc acagccaggt atgagcgatt gattcaccat caaggcgata
      241 cggtgtgacc accagggaag agtcctggct acaacacgag agcgcacttc atcgactcaa
      301 ctttgagctt tgtcgttaaa ttttgaaatg gcggagtgcg ctcccggttg tggtgaacag
      361 gtgtttaacg ggaactccct gcccgttacc cggttcgatt ccgggcgccc atcatcaatt
      421 tgctgtgttt agtctttgcc cagtccgcac gatgggccat tttttcacac agccaggttt
      481 tatcgctgtg cctgagtccc caacaggaga ggccaaaccc gcagcgtgac accagggaaa
      541 gaccggagga agtaccacgc ctgaccagcg ttgaccatga gcctgaccag ctcaaaacag
      601 gaaagaccag cccgggcctg accagccctg tacggtcgta atggaaacat aacgacgccg
      661 gaaacgtaac cggcaccctt tagatagcaa aagacccgca caaggcgggc cagttacccc
      721 gaacggcgac caaaccattc ggatttatca caagtgacca aacttgtgat gaggaaagac
      781 caacgacact gacgctatgg aagctgatca atattcgctg atcggctctg agtatacatt
      841 accaaggagt cgctatggaa gcgcgcacca tcccagtaac actctttatt cattatgcaa
      901 cttcaacttt cagccacgaa aagctgcttg ttgcgactgt tgatatgtca aaaaattttc
      961 cagacaggta catccttctg gaaagccgcg aaattgaaat taccgttaac cagcccgagc
     1021 caatcgacat catcggttta caggtcgagc aactgcgtga acaaaaacag aaaacagtcg
     1081 ccgacgccca acagcgtatt gctgctatcg atgacaaaat ccagcagtta ctttgcatcg
     1141 aatacacgcc agataccgat gagctcccct actaaaaacc actgacctgt aatgaggaaa
     1201 gaccaatgac catttttaac ggcttgttag aagcgaaaaa aggcgcgctc aaaaacggcg
     1261 cgatcccggc gctggccatc gccatcgccg cccctaacaa aaaagttgcc gagaacatca
     1321 tcatcggcaa attgtgggaa gcctaccctg accacggcga caactatttc aaacctaaaa
     1381 tctgggaaga tgccccgggc caaccgcgcc caggcgtcgg tgagtttgat gagacgtttg
     1441 ccacagaaca cagttttgat ggcgaaaaat gggtagttaa cactcctgtt gattcagatt
     1501 gcagttcagc agatatctca caggttagcg acctgatgaa actgccggct cgtgaacgat
     1561 tcgccgccgt tctgctgttc agccacgacg ccaacgaagt cgacagtgaa ttgcttgtgc
     1621 agacgcgtga atacctggag atgctcgata acagtgatac tgacagtgag gatgaggttg
     1681 acgcgtttaa ccgcatcgtt cttgatgcca tggtggcgtg taagcccatc gagtacatgc
     1741 atattgctgg attgaataat ctggtacatg caattttggc aagttgcgat acccaggaac
     1801 aaaacccgac cagttggact atctccaaat ttataaaaaa atgggtagag aatcccggta
     1861 aacgagatga aatgctgccg gaggtaaaac cagaaacagc atccgcacgt ccttacaaac
     1921 agactcacgc cactctggat cgtgaaattg cctgcgccct gttacctgtt gccccggaaa
     1981 aaatcacccc cagcatcctg aaagcggcag acgaaataat cagtcaggac agggaagatt
     2041 ttaaacgctg gtcaatggcc ttgcgcacaa cggatcagat ccttgcctat gaccgcgcat
     2101 cagtattcgg tgttattcag agcgcccccg caaaagacac gtaccacttc ccacaatccc
     2161 tgcgcagtca catcgacaac tggctgcaag ctaacgggca gcgtgatgca aatgctgttg
     2221 aagagaagcc aaaggaagca gcacccaagg atgatgtaaa agtcaccaac cacggcggcg
     2281 gacgattctc aattgatggg atgatgtcag aaacaccctc aaatcagggc gaaaaaagcg
     2341 aagctgcaaa tgctggagaa cgtagtttgc agcagttgcg tgagcagttt gtcacgcctc
     2401 gccatgtgta tgacgtacct gaaaataacg ccgtatcaca gagggaacct gcagctatta
     2461 ccctggcaga agagactcct ccacaagaac aacttagcga gcaggtaaag gatctggtgc
     2521 agaacgttga cgcgctggtt gagcggatcc atgccgaaga gcacaagcgg cagaatgcaa
     2581 tctcagctat cgaaacggag ttaaaggact cagatgacac ggataacctg gcattgtgga
     2641 agaacgtatt caaaaccgat gagcgcttca ccagtgcttt ctctcagaat ggcggcggca
     2701 catccatcaa cggcacttat atagcgatga aagcgactcg cgaatttggg ccatttggta
     2761 ttggctgggg ggtagaggtg ctggaggagc gctttgataa aggcgcacca atagttcgca
     2821 aaaaacaggt tggtgaaaaa atagaatggg atctgattca agacggtgtt ggcgggtacc
     2881 tatgtgaaat gcaccacacc atgaaagtga gagtctggta catattgaat ggggtacgcg
     2941 gtgagtccga ggcttacgga tgcacacctt atatctacga cactaaatac ggaccaacaa
     3001 gcgacggcga agcaccgaag aaatcctgga cggatgctgt taagaaagcg ctatcccctc
     3061 tcggattcag cgccgatatt ttcatgggcc tgtacgacaa tccggaatac cgccagagga
     3121 ataaagctga gtttgatatc aagaatgcca gcgagaatgc ggaagatgct acccgtctgc
     3181 gtaaggaact ggatgagaag cttatcaacg ttgccaatac gctggccgcc gcggtaaccg
     3241 ccaacgaagt aaacaaggta tttggcctca tcgcccgcga agtggatgta cacaggaaag
     3301 cagcggaaac caaaggcgat aaagaatatt catcgtatct gggatcacgt ctgcgccgta
     3361 tcaccgacat taaaactgaa cgcctcgccg cccttaccgc tgcacaggag caaacagcat
     3421 gagcactgct atcgctattg caaaagaata tgccagtctg attgacctgt tagaaaccgc
     3481 cgatgaactg acgccagaga tgatcgccga cacgcttgaa ggcatggaag gagaactggg
     3541 agacaaactg gacgccatga tggtcatctg ccgtaattta cagggcaatg ccaatacctg
     3601 cgctgaagaa atgtctcgcc tggcaacccg taagacgtcc tttgaaggca aggaaaaagc
     3661 aattcgaaag catatgctca cctgcctgca agctgctggc ctggataaac tgaaaaccgc
     3721 aaaaaacaca tttactgatg cacagggggc tatccgggta attatcgata gcaaagataa
     3781 gatcccggat gagtatgagg gcgtgtcact tgttgatgta gaaacggtta ttacaccaaa
     3841 caagcgagcc attaaagaag tgattgaatc tgcggaggcg gttgccgccg aaatactggc
     3901 gcgtggagaa acaccaccag ccgagttatt aaacccggta ccaggcgcac atctggaacg
     3961 cggcgaacgg tcactgagga tacgctaatg cttaaactca cattaaagcg tggtgacgcg
     4021 gttcacctgg tacttgccga tggtaccaat ggcattattg aagcacggag ccgctgcgaa
     4081 cttgggctac acctgccaga aaacattaag gtcactcggg agaaatcggc attcacccca
     4141 caagaactga ttacgcctaa tcagaaataa aaactcacca tcgctagcat tgcgattcac
     4201 cagacaccgg aggatcacaa tgctgcgatg gcaaccggga gcaactctgc tctccgcatt
     4261 tgatatcaaa attggtcgac tgtcggccag cgtcaggaaa cagactttga ccgagtctga
     4321 tattgcccgt gcctgccaga aggcagatga cgcaataagc tacataatga ggaaagacca
     4381 tgaaaagcga tcacgacata atcaccagag aagaaatggt cgagctgacg ggaagcccac
     4441 ttaaatcaaa gcaatgtgag gctcttcgcc gggctggaat tttcttcatg gaaagggctg
     4501 acggacaccc aaaaacaacc tggggccatt tcatgaaccc aataaaattt cgcaatttac
     4561 aggaggtgac gacgcgaaaa gatgatgaac ctgattttgg agcaatattt aatggccgga
     4621 aagagaaaga acccagcaga taactggatg ccgcctcgtg tttaccaggg caaagcggcc
     4681 tacgaattca ggaataaaga taacaaagcg atacgcctgt gcgcattgga tgcaccacga
     4741 tcagccgtat ggctggcata tgaaaaagcg gtcggtgacg aaaaagaaag aaatactttt
     4801 caggcgctca cggaacaatt catgacctcc cctgatttta tggatttggc agtcgaaacc
     4861 cggaaagact acacaaaata ttccggaaaa gttctgcctg tcttcgggaa gatcgacccg
     4921 gataaaatca aacctgaaca tattcggcgc tatatggatc aacgcggttt atcaagccga
     4981 actcaggcaa acagggaaaa aagctttatg tcccgggtat tccgttgggg ttatgaacga
     5041 ggttatgttc agaggaatcc ttgtcaggga gttaaacagt ttaaagagaa agctcgcgaa
     5101 cgttatatta cggatgaaga atatcaggcc gtttatgaag tgtctcctga tgttgttcgc
     5161 gtagcaatgg agattgccta cttatgcgtg gccagacaga gtgatgtact ttcattgcag
     5221 aaagaccagc tgttcgattc cgggatctac attcgtcagg gaaaaaccgg cgttaagcaa
     5281 atcaaagcct ggtcgcctcg tctgcagaaa gcgatagctc tggctcgttc tctgccatta
     5341 aaaacgggaa tcagtagcct gtttgtgatt catcaaacta ccggtggcaa gtatacccgt
     5401 gatggtttta actctcgttg gcgtgatgtc aaagcggcag cacaggaaaa atatcctcat
     5461 ctgcaaatag acttcacatt tcatgatctg aaagcaaaag gtatctctga tctggaaggc
     5521 agcctggaag agaagcaagc aatttccggg cataagaacc cgcgacagac agcagcatat
     5581 gaccggaaag ttaaagtagt gcccgtagtt ggtggccaga gaaaatgaat gatgatgcgt
     5641 ccagagaaaa atcatcttcg gacgcatctt cggaaatgag aaagaagata caaaaaaacc
     5701 acccgaaggt ggtttcacga cactgcttat tgctttgatt ttattcttat ctttcccatg
     5761 gtacccggag cgggacttga acccgcacag cgcgaacgcc gagggatttt aaatcccttg
     5821 tgtctaccga ttccaccatc cgggctcggg aaaaaagtgg aggcgcgttc cggagtcgaa
     5881 ccggactaga cggatttgca atccgctaca taaccgcttt gttaacgcgc caaattcttc
     5941 aggcctttca gccagacatc cgctgacgcc gatgcctttt aaactggagc gggaaacgag
     6001 actcgaactc gcgaccccga ccttggcaag gtcgtgctct accaactgag ctattcccgc
     6061 attcatcaag caatcagtta atcacttgat tttattatcg tctggcaatc agtgccgccg
     6121 ttcgatgcgt tgcattctac ttacctggcg cgatgagtca acgatatttt tcaccacttt
     6181 tgatcgtttg ctgaaaattg cgccgaaacg atcactgatc aagcaaatct gcacgcgcag
     6241 cgctcaaata ttgcaacatt gaccacagag tcagtaccgc agccacaaag aaaagtgcaa
     6301 taccggcgta ctcaacccaa atattcggac gccacagcag ccatgccaac gccaccatct
     6361 gggcagtggt tttcactttt ccaatccagg agacagccac gctactgcgt ttacccaact
     6421 ccgccatcca ttcgcgtagc gcagaaataa taatttcacg ggcgatcatc gttgctgccg
     6481 gtaaggtcac ccaccagctg tggtaatgct cggttaccag caccatggcg atagccacga
     6541 gaactttatc tgcgacaggg tcaaggaaag caccaaaccg ggtactctga ttccagcggc
     6601 gtgccagaaa accatcgaac cagtcagtca ccgccgcgac gcagaaaatg agcgcggcgg
     6661 caaacggcga ccaggtgaca ggcaaataaa agaccaatac aaagaatggg ataaggatga
     6721 cacggaacag tgtaagcaac gtagggatat taaattgcat aatgacgggt aactatctgt
     6781 tgtcagtaag attaccccta tgttgctaca gagacatcaa tgtttcaacg accagaagat
     6841 cttttctgcc agaccttgcg aaatacccgg cacttttgca atttcctcga cgctggcgtt
     6901 acgtaaacct tgcaaaccgc ccatatattt caacaacatt tgccgacgtt ttggcccgac
     6961 gccttcaatg gtttccaggg aactggtatt tttgaccttc gcccgttttt tacggtgccc
     7021 gccaatcgcg tgatcgtgtg attcatcgcg aatatgctgg ataacatgca gcgcgggaga
     7081 atctggcggc aaactaaatc cctcaccttc cggctcaaag aacagcgttt ccagcccagc
     7141 cttacgatct gctcctttgg caacgccaag tagcagcgga tgatttttat cccatgagac
     7201 atccagttcg gcgaaaacat ttttcgcctg cgcaagctgg cctttgccgc cgtcaataag
     7261 gatcacatcc gggatcttac tgtcgtcgat agctttacca taacgccgac gcagcacctg
     7321 attcatcgcc gcgtaatcat cgcccggcgt gatgccagta atgttatagc gccgatactc
     7381 cgcacgcagc gggccgttgg catcaaacac cacacaggaa gcgacggttt gttcacccat
     7441 ggtatggctg atgtcaaagc actccatccg cttcacttcc ggcaatttca acacgctggc
     7501 aagcgcggtc agccgctggt gaacggtaga ttgctgcgaa agtttgctgg ttaaggccgt
     7561 cgccgcattg gtacgcgcga gtttcagata acgcgctcta tcgccacgag gtttggtttg
     7621 aacattaatc ttgcgtcccg ccagttctga aagggaatcg gcgagcagcg ttttatcgct
     7681 aagattaaaa tcgagcagga tctcacccgg taaggtgcgc atctggctgc cttgtaaata
     7741 gaactgacct acgaaggttt ccaccacctc gctcagttcc gtaccgccag gcactttcgg
     7801 gaaatagctg cggctgccga gcactttgcc ctgacgaatg aacaatacgt ggacacaagc
     7861 catacccgca tcgaacgcca ctccaataac gtcaaggtcg tcgccggtat tggaaacaaa
     7921 ctgtttttcg gtgacacgtc gcaccgcctg aatttggtcg cgaatccgcg ccgcttcttc
     7981 aaactccaga ttctggctgg cagtttccat acgactaatg agttgcgtaa gcacctgatc
     8041 atctttgcca gacaaaaaca ggcgcacata ctcgacctgc tgagcgtatt cttcttcact
     8101 caccagtcct tcaacgcacg gccccagaca gcgccctatc tgatattgca gacacggacg
     8161 cgagcggttg cgataaacac tgttttcgca ctggcgaatg gggaaaatct tttgcagtag
     8221 cgccagtgtt tcacgtacgg catagccatt cgggaacggg ccgaaatatt cacctttggc
     8281 atgcttcgct ccacgatgca tcgccagacg cgggtgggta tcgccactca ggaagataaa
     8341 aggatatgat ttatcatcgc gtagcaaaac gttgtaacgc ggctgataaa gtttgatgta
     8401 gttgtgttcc agtaacagcg cttcggtttc tgtatgagta accgttacat caatttgctg
     8461 gatctgggcg accagcgctt cggttttgcg cgaagcgagg ttgctacgga aatagctgga
     8521 aagccgtttt ttcaggtctt tcgctttgcc gacatagata accgtaccac cagcatcata
     8581 catgcgataa acgcctggct ggctggttac ggtttttaaa aacgcttttg cgtcaaactg
     8641 atcactcact gacttgataa tgtctccgca ttacacagac catggcgaat tgccaggtga
     8701 gtcagctcaa catcgccatg aatgtttagt ttactgaaca tacgatagcg gtagctgttc
     8761 accgttttcg gactgagatt gagctgttct gagatctcat tgaccttctg gcccttggtg
     8821 atcatcagca taatctgcaa ttcacgttca gacaaactgg caaatgggct ttctgttttt
     8881 tctggttcga tctggcttaa cgccatttgt tgagcgatat cagaagcaat gtaacgctgc
     8941 cctgaataga cagaacgaat cgcactcacg acttcctgcg gagccgcgcc tttgctgagg
     9001 tagcccgcag ctccggcctg catgactttc gctggtaaag ggttttctgt atggacggta
     9061 agcatgatga ttttgacatc agctgtggaa cgcgcgattt tacgcgtcgc ctcaagaccg
     9121 ccaatgcccg gcatactcat gtccattagc accacgtcaa cggcatttgc ccggcaccat
     9181 ttaacggcgt cttcaccgca cgatgcctca ccgacgactt ttataccctt tatatcttcc
     9241 agaatgcgtc gtatccctgc gcgcaccagt tcgtggtcat caacaagtag aacgttgatc
     9301 aaaggaatat ctccagaaat agggataacg ctactgatag ttagtcattc gtatattagc
     9361 ggtttttatt gcaactttga aacgttaaaa atggtgggta ttcgattttt ctctcgtttt
     9421 tgtcaattcg attgtccaca gttatggtca cgcccgtcac caacggcttc cgggatcgtt
     9481 tcacagtaag cccggcgatg aaatgtgaca aaaattgact ttattcagca aaaatgaaaa
     9541 tcagcccgct gaatatgtaa cattaattaa cccgaacaat acgggcaaaa aacattcatg
     9601 ataaaaatat ttattggtca ttatattaac gtattttata gtactgttga tatcacgctc
     9661 aaaaaacaac cactgctatt tttagcaaag cttatggtat actccgccgc cttaacattt
     9721 ttcaccgcaa attttcattg caacatgacg aggaaaataa atgagtacgc ctgatttttc
     9781 tactgccgag aataatcaag aactggcaaa tgaagtctcc tgcctgaaag cgatgctgac
     9841 gctgatgctg caggcgatgg gacaagctga cgcgggccgc gtgatgttaa agatggaaaa
     9901 acagcttgcg ctgatcgaag acgaaaccca ggctgcagta ttttccaaaa cggttaagca
     9961 aattaaacaa gcctaccgtc agtaatataa aaccggctga gagcgtgcct ttcagccggt
    10021 ttttgcatct ggcacgcaga acagaaaaga gatcaaatta agccagtagc ggccgcgtaa
    10081 caggcaacct gcgtcttatt cggtgcattg atttttttct gcatgttttt ctgatggaaa
    10141 ttgaccgtat tctcagagat tgacaaaatc atcgctatct ctgctgatgt cttaccttcc
    10201 gccgtccatt tcagaatttc tttttcgcgc ttgctgaaat tcatctctgg cgtcatcact
    10261 atttcatcat ttaaacgcat cagagccatc agactttcgc gcaccagtag ctgcattttt
    10321 aattgcagtt catcactaag aatgggtatt tcgcgcgtgc tgcaacggga aaaggacaaa
    10381 aagcccaacg cccgatttgg cagcattaaa tactgagtga caccgcggcg taaaccatgt
    10441 gcgcgcgcag cttcccataa cggctgtgct tcgctgaata agtcatcatt ccacattaaa
    10501 tggccctgac taaagttttc agggttcagc accggatcaa ttgcgagaaa attttttgcc
    10561 tgataataac taacccacga ctcagggtaa ttggtgtaga aagccacttt aggtcgcgtg
    10621 aatggtaccg ggtggcgaac acataacgaa tagtaatcgt actccagctg ctgagcctga
    10681 agctctattt catggtagac ctcttctgcg gcctccatcc tctgaaaacg caacagcatc
    10741 gtgcgaagcc agctgaaaaa atccgtatcc tgcatagtaa accg
//
LOCUS       DAFGPF010000150        10778 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFGPF010000150 DAFGPF010000000
VERSION     DAFGPF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10778
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.150"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            74..1804
                     /locus_tag="LSX49_004536"
     CDS             74..1804
                     /locus_tag="LSX49_004536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acyl-AMP ligase"
                     /protein_id="HBL7170836.1"
                     /translation="MVYMSNKIFTHSLPMRYADFPTLVDALDYAALSSAGMNFYDRRC
                     QLEDQLEYQTLKARAEAGAKRLLSLNLKKGDRVALIAETSSGFVEAFFACQYAGLVAV
                     PLAIPMGVGQRDSWSAKLQGLLASCQPAAIITGDEWLPLVNAATHNNPELHVLSHAWF
                     KALPEADVALQRPVPNDIAYLQYTSGSTRFPRGVIITHREVMANLRAISHDGIKLRPG
                     DRCVSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVA
                     PPFGYELCQRRVNEKDLAELDLSCWRVAGIGAEPISAEQLHQFAECFRQVNFDDKTFM
                     PCYGLAENALAVSFSDEASGVVVNEVDRDILEYQGKAVAPGAETRAVSTFVNCGKALP
                     EHGIEIRNEAGIPVAERVVGHICISGPSLMSGYFGDQISQDEIAATGWLDTGDLGYLL
                     DGYLYVTGRIKDLIIIRGRNIWPQDIEYIAEQEPEIHSGDAIAFVTAQEKIILQIQCR
                     ISDEERRGQLIHALAARIQSEFGVTADIDLLPPHSIPRTSSGKPARAEAKKRYQKAYA
                     ASLHVQESLA"
     gene            1801..2715
                     /locus_tag="LSX49_004537"
     CDS             1801..2715
                     /locus_tag="LSX49_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001481799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL7170837.1"
                     /translation="MNQTVAVTGATGFIGKYIIDNLLARGFHVRALTRTARAHVNDNL
                     TWVRGSLEDTHSLSELVTGASAVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESGF
                     CQRFLFISSLAARHPELSWYANSKHVAEQQLTAMADAITLGVFRPTAVYGPGDKELKP
                     LFDWMLRGLLPRLGTPETQLSFLHVTDFAQAVGQWLSAETVQTQTYELCDGVAGGYDW
                     QRVQQLVADVRCGSVRMVGIPLPLLTCLADISTALSRLAGKEPMLTRSKIRELTHADW
                     SASNNRISEDINWFPGISLEHALRNGLF"
     gene            2747..2995
                     /locus_tag="LSX49_004538"
     CDS             2747..2995
                     /locus_tag="LSX49_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL7170838.1"
                     /translation="MVNREIVMDYILSCLQDLVENGVEIKPDSDLVNDLGLESIKVMD
                     LLMMLEDRFDISIPINILLDVKTPAQLMETLLPWLENK"
     gene            2995..4167
                     /locus_tag="LSX49_004539"
     CDS             2995..4167
                     /locus_tag="LSX49_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL7170839.1"
                     /translation="MGLYDKYARLAGERLQFSDNGLTPFGTCIDEVYSATEGRIGNKK
                     VILAGTNNYLGLTFNHDAIAEGQAALAAQGTGTTGSRMANGSYAPHLALEKEIAEFFN
                     RPTAIVFSTGYTANLGVISALADHNAVVLLDADSHASIYDACSLGGAEIIRFRHNDAK
                     DLERRMVRLGERAKEAIIIVEGIYSMLGDVAPLAEIVDIKRRLGGYLIVDEAHSFGVL
                     GATGRGLAEAVGVEDDVDIIVGTFSKSLASIGGFAVGSEAMEVLRYGSRPYIFTASPS
                     PSCIATVRSSLRTIATQPELRQKLMDNANHLYDGLQKLGYELSSHISPVVPVIIGSKE
                     EGLRIWRELISLGVYVNLILPPAAPAGITLLRCSVNAAHSREQIDAIIQAFATLKQ"
     gene            complement(4202..5281)
                     /gene="lptG"
                     /locus_tag="LSX49_004540"
     CDS             complement(4202..5281)
                     /gene="lptG"
                     /locus_tag="LSX49_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HBL7170840.1"
                     /translation="MNVFSRYLIRHLFLGFAAAAGLLLPLFTTFNLINELDDVSPGGY
                     RWTQAVLVVLMTLPRTLVELSPFIALLGGIVGLGQLSKNSELTAIRSTGFSIFRIALV
                     ALVAGILWTVSLGAIDEWVASPLQQQALQIKSTATALGEDDDITGNMLWARRGNEFVT
                     VKSLNEQGQPVGVEIFHYRDDLSLESYIFARSASIEDDKTWILHGVNHKKWLNGKETL
                     ETSDNLAWQSAFTSMDLEELSMPGNTFSVRQLNHYIHYLQETGQPSSEYRLALWEKLG
                     QPILTLAMILLAVPFTFSAPRSPGMGSRLAVGVIVGLLTWISYQIMVNLGLLFALSAP
                     VTALGLPVAFVLVALSLVYWYDRQH"
     gene            complement(5278..6348)
                     /gene="lptF"
                     /locus_tag="LSX49_004541"
     CDS             complement(5278..6348)
                     /gene="lptF"
                     /locus_tag="LSX49_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HBL7170841.1"
                     /translation="MKLVEHYIMRGTRRLVLIIVGFLIFIFASYSAQRYLTEAANGTL
                     ALDVVLDIVFYKVLIALEMLLPVGLYVSVGVTLGQMYTDSEITAISAAGGNPGRLYKA
                     VLYLAIPLSIFVTLLSMYGRPWAYAQIYQLEQQSQSELDVRQLRAKKFNTNDNGRMIL
                     SQTVDQDNNRLTDALIYTSTANRTRIFRARSVDVVDPSPEKPTVMLHNGTAYLLDHQG
                     RDDNEQIYRNLQLHLNPLDQSPNVKRKAKSVTELARSAFPADHAELQWRQSRGLTALL
                     MALLAISLSRVKPRQGRFSTLLPLTLLFVAIFYGGDVCRTLVANGAIPLIPGLWLVPG
                     LMLMGLLMLVARDFSLLQKFSR"
     gene            complement(6379..6939)
                     /locus_tag="LSX49_004542"
     CDS             complement(6379..6939)
                     /locus_tag="LSX49_004542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HBL7170842.1"
                     /translation="MSSRLIIALIIMLLAQGVQAHNFVTGKTVTPVYIQEGGELLLNS
                     DDEIHYQKWNSTQLAGKVRIIQYIAGRKSAKKKNSLLIKAVEAANFPQDRFQPTTIVN
                     TDDAIFGTGYFVVGKIEKNKRRYPWAQFVIDGNGLGRVAWRLPEQSSTILVLNKDGQI
                     QWAKDGSLTPEEVDHVIALAQKLINE"
     gene            complement(6951..7775)
                     /locus_tag="LSX49_004543"
     CDS             complement(6951..7775)
                     /locus_tag="LSX49_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170843.1"
                     /translation="MMRKYFPLEASERLFVAVEEDDVVDAQVSLPPTIALSCTTEIIH
                     DNYALCLQFWLNGVNRQELLRLICKQAKGDELTADERKQFKYMRARYKHLRFAQRLYL
                     KKHQAGFLFGKTTVFLGRFQDGFRNGKKNIVSYYGNLLRVYLSSPVWSLVNYSLRHSQ
                     LESVSGFIAYRQKQMHTLKEIIAKPRLTGREFHDVRKIISQQVSYYDTLRSLDPENKE
                     ALQISRFLAAINGLMGDKHDDMVADDMENRQSYDAPVALDSDIRQRLELLISRFPL"
     gene            complement(7775..9124)
                     /locus_tag="LSX49_004544"
     CDS             complement(7775..9124)
                     /locus_tag="LSX49_004544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HBL7170844.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQIWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDR
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYVSNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKSFYPEVMRLDPRTTRPWLLGVKSGLLAGGIGILVALAVLI
                     VGKPLISLVFGVKYLEAYDLIQVMLGAIVISMLGFPQESLLLMAGKQRAFLVAQTIAS
                     IGYIVLLFMFCHLFGVLGAAFAYFGGQCLDVVLSLIPTLKAFFQRHSLLYNAAGEKS"
     gene            complement(9170..9943)
                     /locus_tag="LSX49_004545"
     CDS             complement(9170..9943)
                     /locus_tag="LSX49_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170845.1"
                     /translation="MDALQTQTVNSTTAPQPNYIPGLIAVVGCDGTGKSTLTTDLVKS
                     LQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTQSMKTKSPA
                     LWAAVIMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATG
                     KISMFLAQRERRLYQKMAQYRPELIIRLGIDIDTAISRKPDHDYAELQDKIGVMSTIG
                     YNGTKILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT"
     gene            complement(9975..10688)
                     /locus_tag="LSX49_004546"
     CDS             complement(9975..10688)
                     /locus_tag="LSX49_004546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBL7170846.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAATMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNMTALVIYLLSC
                     WRAYKFRKMLCKSQQGYLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELK
                     LYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGARILELDGR
                     QPADEILQASLRAIQAALS"
BASE COUNT         2668 a         2810 c         2679 g         2621 t
ORIGIN      
        1 tatctcattt atcttttatg cctatataat ccaccgcatt attgtcattt tatttttgat
       61 atccaatttt ttcgtggtgt atatgtctaa taaaatcttt acgcattccc tacctatgcg
      121 ctatgccgat tttccaacgc tggttgatgc tttggactat gccgctctga gtagcgctgg
      181 aatgaatttt tatgacagac gttgccaact tgaagatcaa ctggaatatc agacgttaaa
      241 agcgcgtgcc gaagctggtg cgaagcggtt gttatcgctg aacctgaaaa aaggcgatcg
      301 cgtggcactg attgccgaaa cgagtagcgg gtttgtagag gctttttttg cctgccagta
      361 tgccggctta gtcgccgtcc cgttggcgat tccaatgggc gtcggtcagc gggattcctg
      421 gagcgccaaa ctgcaggggt tactggcaag ttgccagccc gcagccatta tcactggtga
      481 tgagtggttg ccactggtca atgccgcgac gcataacaat cccgaattac atgttttaag
      541 ccacgcctgg tttaaggcat taccggaagc cgatgttgcg cttcaacgtc cagttccaaa
      601 cgatatcgcc tacctccagt acacctccgg cagcacccgt tttccccgtg gcgttatcat
      661 tactcaccgc gaagtgatgg ctaatctacg tgctataagc cacgatggga ttaaattacg
      721 ccctggcgac cgctgcgtct cctggctgcc tttctaccat gatatgggac tggtcggctt
      781 tctcctgacc cccgtcgcca cgcagctttc agtagattat ttgcgcactc aggattttgc
      841 catgcgtcct ctgcaatggc ttaaattgat cagtaaaaat cgcggcaccg tttccgttgc
      901 gccgccgttt ggctatgaat tgtgccagcg ccgcgtgaat gaaaaagatc tcgctgaact
      961 ggatctttcc tgctggcgcg tcgctggtat tggtgcagaa cccatctccg cagaacaact
     1021 ccatcaattc gctgaatgtt tccgtcaggt caactttgac gataaaactt tcatgccgtg
     1081 ctacggactg gcagaaaatg cgctggctgt cagcttctct gatgaagctt ccggggttgt
     1141 ggttaacgaa gtggatcgcg acatcctcga ataccagggt aaagccgtcg cgccgggtgc
     1201 tgaaacacgc gccgtatcga ctttcgtcaa ctgcggtaaa gcgttgccgg aacatggcat
     1261 tgaaatccgc aatgaagcag gtatacctgt cgcggaacgt gtggtaggcc atatttgcat
     1321 ctccggccct agcctgatga gcggttactt tggcgaccag atttcacaag acgagattgc
     1381 cgcgacgggc tggttagaca ccggcgacct cggttatctg ctggacggtt atctgtatgt
     1441 caccggacgc attaaagatc tgattattat tcgtggccgt aatatctggc cgcaggatat
     1501 tgaatatatt gcggaacagg aaccggaaat tcattctggc gatgcgattg cttttgttac
     1561 cgcccaggaa aaaatcattt tgcagatcca gtgtcggatc agcgatgaag aacgtcgcgg
     1621 gcagcttatc cacgcgctgg cagcacggat ccaaagcgaa tttggcgtta ccgcggatat
     1681 cgatctgttg ccgccccaca gtattccccg aacatcctcc ggcaagcctg cccgtgcgga
     1741 agcgaaaaaa cgttatcaga aggcttatgc tgccagtctt catgtgcagg agtccctggc
     1801 atgaatcaaa ctgtcgcggt gacgggcgct accgggttta tcggtaaata tattattgat
     1861 aacctgctcg cccgcggctt tcacgttcgc gcattgacgc gtactgcccg cgctcacgtc
     1921 aatgataatc tcacttgggt gcgcggttcg ctggaagata cacattcgct tagcgaactg
     1981 gttaccggag ccagcgcggt ggtccattgc gccgggcaag tgcgcgggca caaagaagag
     2041 atttttaccc gctgcaacgt tgacggcagc ctgcgcctga tgcaagcggc aaaagagagc
     2101 ggcttttgcc aacgatttct gtttatctct tcgctggcgg cgcgccatcc cgaactctcc
     2161 tggtacgcaa attccaaaca cgtcgccgaa caacagctga ctgcaatggc tgacgcaatt
     2221 acgttgggcg tttttcgccc gacagccgtg tatggtcccg gcgataaaga gttaaaaccg
     2281 ctgtttgact ggatgctgcg cggtctgctg ccacgacttg gcacgccaga gacacagctc
     2341 tctttcctgc acgtcaccga ttttgcgcaa gcagtgggtc agtggttaag cgccgaaact
     2401 gtacagacgc aaacctatga attatgcgat ggcgtcgccg gaggctatga ctggcaacgt
     2461 gtccaacagc ttgttgccga tgtccgctgt ggttccgtgc ggatggtcgg tattcctctg
     2521 ccgctactca cctgccttgc ggatatcagt accgcgttga gccgtctggc gggtaaagaa
     2581 ccgatgctga ctcgttcgaa aatccgtgaa ttaacccatg ccgactggtc ggcaagtaat
     2641 aaccgtattt ctgaagatat taattggttt cccgggatta gcctggaaca cgcattacgc
     2701 aacgggctat tttgattgtc ttgtttaaag gtgtgttaac gtttctatgg taaatcgtga
     2761 aatagtaatg gattacatcc tttcctgttt acaggatttg gtcgaaaacg gtgtggaaat
     2821 taagcccgac agcgatctcg tcaacgatct tggcctggag tcgatcaaag tgatggatct
     2881 cttaatgatg ctggaagaca gattcgatat ttccattcct attaatattc tgctggatgt
     2941 caaaacccct gcgcaattaa tggaaactct acttccatgg ctggagaata aataatgggg
     3001 ctatacgata aatatgcgcg ccttgctggc gagcgactgc aatttagtga caacgggtta
     3061 acaccgtttg gcacctgtat tgatgaagtg tattccgcca ccgaaggtcg gatcggcaat
     3121 aaaaaagtga ttctggccgg gaccaataat tatctcggtt taacctttaa tcatgatgcc
     3181 atcgccgaag gtcaggcagc gttagcggcc caaggcaccg gcaccaccgg ttctcgtatg
     3241 gcaaacggca gttatgcgcc gcacctggcg ttagagaaag agattgccga gtttttcaat
     3301 cgccctaccg ctatcgtttt ttcaaccggt tataccgcta atttaggcgt catcagcgca
     3361 cttgccgacc ataacgccgt ggtgttactg gatgccgaca gccacgccag tatttatgac
     3421 gcctgttctc tcggtggcgc agaaattatt cgtttccgcc ataacgatgc taaagatctg
     3481 gaacggcgca tggttcgcct cggtgaacgg gcgaaagagg cgattatcat cgttgagggc
     3541 atctacagca tgctcggtga cgttgcgccg ttagcggaaa ttgttgatat caaacgtcgt
     3601 ctcggtggtt atttgattgt cgatgaagcg cattcgtttg gcgtgttagg cgcaacgggg
     3661 cgcggactgg ctgaagccgt tggcgttgaa gatgatgtgg atattatcgt tggtactttc
     3721 agtaaaagtc tggcctcgat tggcggtttt gctgtcggtt cggaagcgat ggaagtgctg
     3781 cgctacggca gccgcccgta tatttttacc gcctctcctt ctccgtcctg cattgcgacc
     3841 gtgcgctcgt cgttaagaac cattgccaca caaccagagc tgcggcaaaa actgatggat
     3901 aacgccaacc atctgtatga cggtctgcaa aaactgggtt atgagttaag ttcacatatt
     3961 agcccggtag tgccagtaat aatcggttcg aaagaggaag gtttacgcat ctggcgcgag
     4021 cttatttcgc tgggcgttta tgtgaatctt atcctgccac ctgccgcgcc tgcaggcatc
     4081 actctgctgc gctgtagcgt aaacgctgcc cacagtcgtg agcaaatcga tgccatcatt
     4141 caggcatttg ctactctgaa gcagtaatgt gagcccgctg tggtgttgcg ccacggcggg
     4201 tttaatgttg tctgtcatac caatacacca ggctcaacgc caccaacaca aacgctaccg
     4261 gtaaaccgag cgcggtaaca ggtgcgctca acgcaaataa caatcccaga ttgaccatga
     4321 tttgatagct gatccaggtg agtaagccaa cgatgacgcc tacagcgaga cggctaccca
     4381 tccctggcga gcgcggggcg ctaaaggtga acggcacagc cagcaaaatc atcgccaggg
     4441 tcaggatcgg ttgccccagt ttttcccaca gtgcaaggcg gtattcgctg ctgggttgtc
     4501 cggtttcctg caaataatgg atgtaatgat taagctgacg gacagaaaaa gtattccccg
     4561 gcatcgataa ctcttcaaga tccatactgg tgaaggccga ttgccaggca agattatctg
     4621 atgtttccag cgtttctttg ccattcaacc attttttatg attcacacca tgcaggatcc
     4681 acgttttgtc gtcttcaatg gaggcactgc gtgcaaaaat gtaggattcg agcgagagat
     4741 cgtcgcgata atgaaatatc tccacgccca caggctggcc ctgctcgttc agcgatttca
     4801 ccgtcacaaa ttcattaccg cgcctggccc aaagcatatt gccggtaatg tcatcgtcct
     4861 cccccaacgc ggtggcagtc gatttgattt gcagcgcctg ttgctgcaat ggcgacgcca
     4921 cccactcatc tatcgcgcct aacgaaacag tccacaatat cccggcaacc agcgccacca
     4981 gtgcaatacg gaagatagaa aacccagtgc tgcgaatggc ggtaagctca ctgtttttcg
     5041 ataactgccc caggccaaca atccctccca ataatgcgat aaacggcgaa agttcgacca
     5101 gtgtacgcgg taaggtcatc agcaccacca gcaccgcctg agtccagcga taaccgcccg
     5161 ggctgacatc atccagttcg ttaatcaggt tgaaggtggt aaaaagcggc agcaatagcc
     5221 ctgcggcggc ggcaaaaccg agaaagagat gacggattaa atagcgactg aaaacattca
     5281 tcgggaaaat ttctgcagca aagagaagtc gcgtgcgacc agcatcagca ggcccattag
     5341 catgagtccg ggtactaacc acaaaccagg aatgagggga atcgcaccgt tagccaccag
     5401 cgtacggcag acgtcgccgc cataaaaaat ggcaacaaac agcaatgtca gtggcaataa
     5461 cgttgaaaat cgcccttgcc gcggttttac ccgacttaat gaaatggcca gcagcgccat
     5521 caacaatgct gtcaggccac ggctttgtcg ccattgcagt tcggcatgat cggcaggaaa
     5581 ggctgagcgc gccagctccg tgaccgattt tgctttgcgt ttgacgttag ggctttgatc
     5641 cagcggattc agatgtaatt gcagattacg gtagatctgt tcgttgtcgt cacgcccctg
     5701 atgatcgaga agataggcgg tcccgttatg caacataacg gtcggtttct caggtgatgg
     5761 gtcaaccaca tcaaccgaac gggcgcggaa aatgcgggtt cgattggcag tagaagtata
     5821 aatcagcgcg tcagtcaggc gattattatc ctgatcaacc gtctgcgaaa ggatcattcg
     5881 tccgttatcg ttagtgttaa atttctttgc ccgcaactgg cgaacatcca gctccgactg
     5941 cgactgttgc tccagttgat aaatctgcgc ataagcccac ggccgaccat acatcgacag
     6001 aagggtgaca aaaatactta gcggtatcgc cagataaaga acggctttgt acaagcgtcc
     6061 cggattgccc cccgccgcag agatagcggt aatttccgag tcggtataca tctgccctag
     6121 cgtcacgcca actgacacat acagaccaac aggtaacaac atctccagtg caatcagcac
     6181 tttgtagaaa acgatatcca gcacaacatc aagagctaag gtcccatttg ccgcttcggt
     6241 cagataacgc tgtgcggagt agctggcgaa aataaagatc agaaaaccga cgataatcag
     6301 caccagacgg cgcgtaccac gcatgatgta gtgttcaacc agcttcatct cactaacacc
     6361 ctcaatcctt tgaatttttt attcattgat cagtttctgc gccagcgcaa tgacatgatc
     6421 tacctcttcc ggcgtcaggc tgccgtcctt tgcccactga atttgcccgt ctttattcag
     6481 caccagaatg gttgaactct gctccggcaa ccgccaggca acgcgtccca gtccattgcc
     6541 gtcaataacg aattgcgccc acggatagcg gcgtttattt ttttcgattt tgccaacgac
     6601 aaaatagcca gtaccaaaga tggcatcatc ggtgttcaca atggtggtgg gctgaaaacg
     6661 atcctgcgga aagtttgccg cttcaaccgc tttaattaac agtgagttct ttttcttcgc
     6721 cgacttacgc ccggcgatat actggataat gcggactttt cccgccagct gtgtgctgtt
     6781 ccacttttgg tagtgaattt cgtcgtcgct attcagaagc agctcgccgc cttcctggat
     6841 ataaacgggg gtaaccgttt tgccagtgac aaaattgtgt gcctgcacac cctgggctaa
     6901 gagcatgata atcagcgcaa taatcaaacg agatgacatc attgctccgg ttatagcgga
     6961 aaacgcgaaa tcagcagctc taagcgctgg cgaatatcgc tatccagcgc caccggtgca
     7021 tcatacgact ggcggttttc catatcatcc gccaccatgt cgtcgtgttt atcccccatc
     7081 aggccattaa tggcggcgag gaagcgggaa atctgtaacg cctctttatt ttcaggatca
     7141 agcgatctta aggtgtcgta ataagaaacc tgctggctga tgatttttcg cacatcatga
     7201 aattccctgc cggtgagtcg cggtttggca attatctctt tcagggtatg catttgcttt
     7261 tgccgatagg caataaaacc gcttacgctt tctaactggc tatggcgtaa tgaatagttc
     7321 accaacgacc agaccggaga gcttaaataa acccgtaaca agttgccgta atacgacaca
     7381 atatttttct taccgttacg aaaaccgtcc tgaaaacgcc ccaaaaaaac ggtcgttttg
     7441 ccgaataaaa atccggcctg atgcttcttt aaatacagcc gttgcgcaaa acgcaggtgc
     7501 ttgtagcgcg ctcgcatgta tttaaattgt ttgcgctcat cagcagtcag ctcatcgcct
     7561 ttggcctgtt tgcatattaa acgcagtaac tcctggcgat tgacgccatt gagccagaat
     7621 tgcaggcata acgcgtaatt atcatggatg atttcggtgg tacaacttag tgcgatagtc
     7681 ggcggcaaac tgacctgtgc atcaacgaca tcatcttctt caactgcaac aaataaacgc
     7741 tcgctcgcct caagcgggaa atattttctc atcatcagga tttctctccg gctgcgttat
     7801 aaagcaagga atggcgctga aaaaatgcct ttaaggtcgg aattaacgag agcaccacat
     7861 ccagacattg cccaccgaaa taagcaaacg ctgctcccag cacgccaaac agatgacaga
     7921 acatgaacag caatacgatg tagccgattg aggcgatggt ttgcgccacg agaaaagcgc
     7981 gctgttttcc cgccatcaat agcaatgact cctgtgggaa gcccagcatc gaaatcacaa
     8041 ttgcgcccag catcacctga atcaggtcat acgcttcgag atacttaacg ccaaacacca
     8101 gcgaaataag cggcttgccg acgatcaaca ccgcgagcgc caccagaata ccaattccgc
     8161 ccgccagtaa acctgacttc acgcctaaca accacggtct ggtggtgcgc ggatctaaac
     8221 gcatcacctc tgggtaaaaa cttttgccca gtaaacccgc tggcgttccg gcggcgtcga
     8281 agaatgtcat ggcgatttta aataacccgg cggcagcggg tcctaacacg atccccacca
     8341 gcactgtgct gcacgagtta cgcgccgacc agatggagtg ggcaatgttg gttgaccaga
     8401 caaaactcca cgcgccttta atgtgtcggg cagactcaaa cagattcaat ttgaaggcgt
     8461 tatggatatt tctgcggcgt aattcgcgcg cggcaaacca ccagtacatg gtgccgccaa
     8521 ccagattcga cacgtaccag gcaataacaa aacccgcaaa accaaagtca aaataccagg
     8581 ctacgacgct ccccgctgcg cgcagaaaag gtttcgtcgc ttgctgtaca gcaattagat
     8641 cgaagcgatc taccgcacgc agaatgccgg tcggcgtgga ggaagccatt gaaggaatga
     8701 gcgtgcaata cagcgctgcc agccaaaagc tttggtcatc cagacctaat gaatgggaaa
     8761 gaaaagggag taaggcaatg ccgccgacaa tcgccaccgc gccgctgacg atatccagcg
     8821 agaaggaaaa tgagacgaca ttgcggaatt gctgcggatt attgttggtt aatgctggtg
     8881 ttccgtactg aaccaccagc tgccatatct gaaacttaat aaaatcgctg atcgacttgg
     8941 cgtacgattg tacaatcacc agtacgccaa acatggcggg cgtcatccct ttaccggcac
     9001 acgagagcgc caacagaccc agtaaagcgc tcacgacatt actggagcct aaccaggcgc
     9061 tattgcgaat aatggtgcga aacgcgccat ctgcaaacca atgtttgatg ttaaaacccg
     9121 ccaattcagc ctgaccttat cgttgatagt aaaaagtatc ccgccagcct taagttaaac
     9181 ttcggcggtc agaaacgatg gcaaccagag aaaccgcctt ctgtgcctgt tccagcactt
     9241 cgctgtaggg cgctctggaa tcaatctcaa gaatttttgt gccgttatag ccaatcgtcg
     9301 acatgacgcc gattttgtcc tgcagctcgg catagtcatg gtcaggcttg cgggagatgg
     9361 cagtatcaat atcaatcccc aaacgaatga ttaattcagg acggtattgc gccatttttt
     9421 ggtataaacg ccgttcgcgc tgcgccagaa acatgctgat tttcccggtc gcacgttcga
     9481 cgccgatccc cggtccgtca taataaaagc ccgaaatttc agcctgcggg aagcgatcgc
     9541 tgaccaccag aacgccactt tgcgccagtc gctgaacctt gcgtagattc gccattcttc
     9601 gcagcgagaa gcagtacata atcaccgccg cccatagcgc tggagatttg gttttcatgc
     9661 tttgggtttt catgctttgg gttttcgatg atttggccgc cagtcgcctt tcgagccaga
     9721 cgccaaccaa cggcaatcgt ttgattttgt cgccgtcttc gcccgagagc agccccagat
     9781 agcgccgctc ggtttgccag tgttgttgca gcgatttcac gaggtcggtg gtcagtgtgg
     9841 atttaccggt gccatcacac ccgaccaccg caatcagccc cggaatgtag ttgggctgcg
     9901 gcgcggttgt actattaaca gtttgtgttt gtagtgcgtc cattcgttaa atcatcccct
     9961 atccattttg gtgatcagga aagcgcagct tgaattgcgc gtagtgacgc ttgcagaatt
    10021 tcatcggctg gttgccgacc atccagttca aggatcctgg cgccattaaa tgtcagttgc
    10081 ggcgtaacgg cgattttttc ctgtaacgcc gccagttggt ggtcaggttt acgcgcaaac
    10141 gcggtttgtt catcaatgcc aagacgaatc aacaatacgg gcaaataaga tgccatccat
    10201 tggtacagct tcagctcgcg ctgccttaac atttttatcc aaccgttacc gcccgtggtt
    10261 tttgccaatt gcgggccatc aaagcgaaaa cccggcactt caacctgcgg gtagcggtcg
    10321 gtgatgagca gatagccttg ctggctttta cacaacattt tgcgaaactt atacgcccgc
    10381 cagcaggaaa gcagatagat aaccagcgca gtcatattgc caggcggtgt ggagggcttt
    10441 tcgtgcacat gtgccgcttt acttcgcaga taacgcccaa aaggtgcgcc aataacaggg
    10501 agctgtgaaa tccattcgcc aattcgcccg gacgattgcc cgagataaat gtgttctgtt
    10561 ggcattgttg ctgccagttc atttaccagg cttgccgtga gggtcgattt acctgaacca
    10621 tcacatccta caatggcaat aacacgcact ggcgtggaat taattattga catattacgt
    10681 tgattcacga aaaacccggc agcaaataat gtattgaata ttacgtggtc cgtgctcaga
    10741 atatccgttc aaccttattg tgacaatggt taattgtg
//
LOCUS       DAFGPF010000151        10565 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFGPF010000151 DAFGPF010000000
VERSION     DAFGPF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10565
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.151"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..232
                     /locus_tag="LSX49_004547"
     CDS             <1..232
                     /locus_tag="LSX49_004547"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170847.1"
                     /translation="VGSSSFTGPKLIIEYQDIEGKTKKVTWQTKLERGVARFSGDNME
                     ADFALRFTPVPEKWTTKGLEKIRKSAANAMFR"
     gene            981..1958
                     /gene="csiD"
                     /locus_tag="LSX49_004548"
     CDS             981..1958
                     /gene="csiD"
                     /locus_tag="LSX49_004548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311547.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HBL7170848.1"
                     /translation="MNALTAVQNNAVDSGQDYRGFTLIPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFQVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGI
                     DDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNIQGGNSLLLHLDDWEHLDLFFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGTLSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ"
     gene            1978..3243
                     /gene="lhgO"
                     /locus_tag="LSX49_004549"
     CDS             1978..3243
                     /gene="lhgO"
                     /locus_tag="LSX49_004549"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HBL7170849.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDIYPDARIALLEKESGPACHQTG
                     HNSGVIHAGVYYTPGSLKTQFCLAGNRATKVFCDQNGIRYDNCGKMLVATSELEMERM
                     NALWKRTAANGIEREWLNAEELREREPNITGLGGIFVPSSGIVSYREVTAAMAKIFQA
                     RGGEIIYNAEVSALSEHKNGVVIRTRQGGEYEASTLISCSGLMADRLVKMLGLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPWPPGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFN"
     gene            3269..4717
                     /gene="gabD"
                     /locus_tag="LSX49_004550"
     CDS             3269..4717
                     /gene="gabD"
                     /locus_tag="LSX49_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HBL7170850.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPK
                     MGADETRAAIDAASRALPAWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGN
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDSVYDRFAEKLQQAVSKLHIGDGLEKGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIIGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            4731..6011
                     /gene="gabT"
                     /locus_tag="LSX49_004551"
     CDS             4731..6011
                     /gene="gabT"
                     /locus_tag="LSX49_004551"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HBL7170851.1"
                     /translation="MISNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYAAT
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANVLGQKLKDG
                     LLAIAEKHPEIGDVRGLGAMIAIELFEDGDHSKPDAKLTAEIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIISQCFAEAKL"
     gene            6248..7648
                     /gene="gabP"
                     /locus_tag="LSX49_004552"
     CDS             6248..7648
                     /gene="gabP"
                     /locus_tag="LSX49_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HBL7170852.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYADVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTSAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLIMWQKTPIHNTR"
     gene            7669..8331
                     /gene="csiR"
                     /locus_tag="LSX49_004553"
     CDS             7669..8331
                     /gene="csiR"
                     /locus_tag="LSX49_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HBL7170853.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSYYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(8332..8781)
                     /gene="kbp"
                     /locus_tag="LSX49_004554"
     CDS             complement(8332..8781)
                     /gene="kbp"
                     /locus_tag="LSX49_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HBL7170854.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLNKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(8865..9023)
                     /locus_tag="LSX49_004555"
     CDS             complement(8865..9023)
                     /locus_tag="LSX49_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HBL7170855.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
     gene            9206..9505
                     /locus_tag="LSX49_004556"
     CDS             9206..9505
                     /locus_tag="LSX49_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7170856.1"
                     /translation="MTELAQLQASAEQAAALLKSMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRGEGLIDCQRDAQRILYSIKNEAVNAIIATLKNVYCP"
     gene            9515..10039
                     /gene="ygaP"
                     /locus_tag="LSX49_004557"
     CDS             9515..10039
                     /gene="ygaP"
                     /locus_tag="LSX49_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HBL7170857.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPPKLRREQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKKAGLP
                     VAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSVFFLLSGFVGAGLLLAGISGFCG
                     MARLLDKMPWNQRA"
     gene            complement(10086..10490)
                     /gene="stpA"
                     /locus_tag="LSX49_004558"
     CDS             complement(10086..10490)
                     /gene="stpA"
                     /locus_tag="LSX49_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HBL7170858.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFIDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
BASE COUNT         2512 a         2692 c         2815 g         2546 t
ORIGIN      
        1 agtcggttct tcatcattca ctggtccaaa attaattatt gaatatcaag atatagaggg
       61 taaaactaaa aaagtcactt ggcaaacaaa attggaacgt ggagtggcac gtttcagtgg
      121 tgataatatg gaggcagatt ttgcactacg gtttacacct gtaccagaga aatggactac
      181 aaaaggtcta gagaagatac gcaaaagcgc cgcaaacgcc atgttcagat aaatatataa
      241 ttaaaacaac aggttaatat ttttcagaca cgggttcaac tcccgccagc tccaccaaat
      301 aatgattgga cggtgtaagg actacaccaa caaaaacagg aagttataag tctcagcagg
      361 acaccgacca gacggtgagg agacaaaaaa ggatacgcaa cggagtcgcg actccctatg
      421 acattaaagc ccgctgatgc gggctttttt attggtcctg acccgccctg aatagaattc
      481 atccaattac agtccagaca tatacagtat ccctcagctc agtatcagct tctcgacaaa
      541 tggtcactgt tatttacccg tttccagaaa gagaataatt tgcccccata gccagccttc
      601 ccggaatctg tatgttcatt aatattgtta tcgatgccat caagtaacat aggttggatg
      661 cgattgatct tactcacatt agtcgacacg gaactcagta agttgaactc tgaaaaagca
      721 gtttaaatag catttaaaca aatgccacca gttcgaaaaa gagtataagc acacttaata
      781 tattgtttta attattcatt tcctttcaac ccaattctta tccctcacat tacttgttat
      841 taatttgctg tttttgatca caataagaaa acaatatgta acttttatgc gcatttttca
      901 gaaatgtaga tatttttaga ttatggctac gaaatgagca tcgccatgtc accctacatc
      961 tcataagagg atcgcttctg atgaatgcac tgaccgccgt acaaaataac gctgtcgatt
     1021 caggccagga ctatcgcgga ttcactctca tcccgtcggc gcaatccccg cgtctgctgg
     1081 aactcacctt caccgaacag acgaccaaac agtttctcga acaggttgcc gaatggcccg
     1141 tgcaggcgct ggagtacaaa tcgtttctgc gttttcaggt aggcaaaatt ctcgacgatc
     1201 tgtgtgcgaa tcagctgcaa ccgctgctgt tgaagaccct gttaaaccgc gctgaaggtg
     1261 cgctgttgat caatgcggtg ggtatcgatg atgtcgcgca ggcggatgag atggtgaagc
     1321 tggcgacggc ggtggcgcat ctgattggcc gttccaattt cgatgccatg agcggtcagt
     1381 attacgcgcg tttcgtggtg aaaaatgttg ataactcaga cagctatctt cgtcagccgc
     1441 accgcgtaat ggagctgcac aacgacggca cttacgtcga agagatcact gattacgtgc
     1501 tgatgatgaa aatcgacgag caaaacatac agggcggtaa ctcgctgctg ctgcatctcg
     1561 atgactggga acatctggac ctctttttcc gccatccgct ggcgcgccgt ccgatgcgct
     1621 ttgccgcgcc gccgagcaaa aacgtcagca aagatgtctt ccatccggtg ttcgatgtcg
     1681 atcagcaggg ccgcccagtg atgcgctata tcgaccagtt tgtccagccg aaagacttcg
     1741 aagaaggcgt gtggttgagc gagctttcgg acgccattga aaccagtaaa ggcactcttt
     1801 ctgtacccgt tcccgttggc aaattcctgt tgattaacaa cctgttctgg ctgcacggtc
     1861 gcgaccgctt tactccgcac ccggatctgc gccgtgaact gatgcgtcag cgtggctatt
     1921 tcgcttacgc cactcaccac taccagacgc atcagtaagc gcaaaggaat tgagcggatg
     1981 tatgattttg tgattattgg cggcggcatc atcggcatgt cgaccgccat gcaactgatt
     2041 gatatctatc ctgacgcccg cattgcgttg ctggaaaaag agtccggccc tgcctgtcac
     2101 cagacgggcc acaacagcgg cgtgatccat gccggagtct attacacgcc cggtagcctg
     2161 aagacgcagt tttgcctggc ggggaaccgc gccactaaag tcttttgcga tcaaaacggc
     2221 attcgctacg acaactgcgg caagatgctg gtcgccacgt ctgaactcga aatggaacgg
     2281 atgaatgcgt tatggaaacg cacggcggca aacgggatcg agcgcgagtg gttaaacgcc
     2341 gaggagctgc gcgagcgtga accgaatatc accgggcttg gcggcatttt tgtgccgtcc
     2401 agcggcattg tcagctaccg cgaagtgacg gcggcgatgg caaaaatctt ccaggccaga
     2461 ggtggtgaga ttatttataa cgccgaagtc agcgccctca gtgagcataa aaacggcgtg
     2521 gtgatacgta cccgtcaggg cggtgaatat gaagcatcga cgctgattag ttgttccggg
     2581 ctgatggctg accggctggt gaaaatgctc ggcctcgaac cgggctttat tatctgcccg
     2641 ttccgcggcg agtatttccg ccttgcgcca gagcataacc agattgttaa ccacctgatt
     2701 taccccattc ccgacccggc aatgccgttt ttgggcgtgc atctcacccg catgatcgac
     2761 ggcagcgtga ccgtcgggcc aaacgcggtg ctggctttca aacgcgaagg ctaccgcaag
     2821 cgcgacttct catttagtga cacgctggag attttaggct cgtcggggat tcgccgggtg
     2881 ctgcaaaacc atctacgctc aggactgggc gagatgaaaa actcgctgtg caaaagcggc
     2941 tatctgcggc tggtgcaaaa gtattgtccc cggctttcgt taagcgatct ccagccctgg
     3001 ccccccggtg tgcgggcgca ggcggtatcg ccggacggca agctgattga cgattttctg
     3061 tttgtcacca ccccgcgcac gatccacacc tgtaatgcgc cctccccggc agcgacatca
     3121 gcaattccta ttggtgcgca tattgtcagc aaggtacaaa cgctgttggc aagccagagt
     3181 aaccccggac gcacgctgcg agcggcacgt agtgtggatg ccttacacgc cgcatttaat
     3241 taataacctt tgaaaacagg atgtagcgat gaaacttaac gacagtaact tattccgcca
     3301 gcaggcgttg attaacgggg aatggctgga cgccaacaat ggcgaggtca tcgacgtcac
     3361 caatccggcg aacggcgaca agctgggtag cgtgccgaaa atgggcgctg atgaaacccg
     3421 cgccgctatc gacgccgcca gccgcgccct gcccgcctgg cgtgcgctca ctgccaaaga
     3481 acgcgccaac attctgcgca actggttcaa tttaatgatg gagcatcagg acgatttagc
     3541 gcgcctgatg accctcgaac agggcaaacc actggctgaa gcgaaaggcg aaatcagcta
     3601 cgccgcctca tttattgagt ggtttgctga agaaggcaaa cgtatttatg gcgacaccat
     3661 tcccggtcat caggccgata aacgcctgat tgtgatcaag cagccgattg gcgtcaccgc
     3721 ggctatcacg ccatggaact tcccggcggc gatgattacc cgtaaagctg gtccggcgct
     3781 ggcggctggc tgcaccatgg tgctgaagcc cgccagtcag acgccgttct ctgcgctggc
     3841 gctggcagaa ctggcgattc gcgcgggcgt tccggctggc gtgtttaacg tggtcaccgg
     3901 ttcggcgggc gcggtcggta acgaactgac cagcaacccg ctggtgcgca agctgtcgtt
     3961 taccggctcg accgaaattg gccgtcagtt aatggaacag tgcgcgaaag acatcaaaaa
     4021 agtgtcgctg gagctgggcg gcaacgcacc gtttattgtc tttgacgatg ccgatctcga
     4081 taaagccgtg gaaggcgcgc tggcctcgaa attccgtaac gccgggcaaa cctgcgtctg
     4141 cgccaaccgc ctgtatgtgc aggacagcgt gtatgaccgc tttgccgaaa aattgcagca
     4201 ggcggtgagc aaactgcaca tcggcgacgg gctggagaaa ggcgtcacca tcgggccgtt
     4261 gatcgatgaa aaagcggtag caaaagtgga agagcatatt gctgatgcgc tggagaaagg
     4321 cgcgcgcgtg gtttgcggcg gtaaagcaca tgaacgcggc ggtaacttct tccagccgac
     4381 cattctggta gacgttccgg ctaacgccaa agtgtcgaaa gaagagacgt ttggccccct
     4441 cgccccgctg ttccgtttta aagatgaagc cgatgtgatt gcgcaagcca atgacaccga
     4501 atttggactt gcagcctatt tctacgcccg tgatttaagc cgcgtcttcc gcgtgggcga
     4561 agcactggag tacggcatca tcggcatcaa caccggcatt atttccaatg aagtggcccc
     4621 gttcggcggc attaaagcct cgggtctggg tcgtgaaggt tcgaagtatg gcatcgaaga
     4681 ttacttagaa atcaaatata tgtgcatcgg tctttaactg gagaatgcga atgatcagca
     4741 ataaagagtt aatgcagcgc cgcagtcagg cgattccccg tggcgttggg caaattcacc
     4801 cgattttcgc tgaccgcgcg gaaaactgcc gggtgtggga cgttgaaggc cgtgagtatc
     4861 ttgatttcgc gggcgggatt gcggtgctca ataccgggca cctgcatccg aaagtggttg
     4921 cggcggtgga agcgcaattg aaaaaactgt cgcacacctg cttccaggtg ctggcctacg
     4981 agccgtatct ggagctgtgc gagattatga atcagaaggt gccgggcgat tttgccaaga
     5041 aaactctgct ggttacgacc ggttccgaag cggtggaaaa tgcggtgaaa atcgcccgcg
     5101 ccgccactaa acgtagcggt actatcgcct ttagcggtgc gtatcacggg cgcacgcatt
     5161 acacgctggc gctgaccggc aaggtgaatc cgtactctgc gggcatgggg ctgatgccgg
     5221 gtcatgttta tcgcgcgctt tatccttgcc cgctgcacgg cataagcgag gatgacgcta
     5281 tcgccagcat ccaccggatc ttcaaaaatg acgccgcgcc ggaagatatc gccgccatcg
     5341 tgattgagcc cgttcagggc gaaggcggtt tctacgccgc gacgccagcc tttatgcagc
     5401 gtttacgcgc gctgtgtgac gagcacggga tcatgctgat tgccgatgaa gtgcagagcg
     5461 gcgcagggcg taccggcacg ctgtttgcga tggagcaaat gggcgtggca ccagatctca
     5521 ccacctttgc gaaatcgatc gcaggcggtt tcccgctggc gggcgtcacc gggcgcgcgg
     5581 aagtgatgga cgccgtcgca ccgggcggac tgggtggcac ctatgccggt aacccgattg
     5641 cctgcgtagc ggcgctggaa gtgttgaagg tgttcgagca ggaaaatctg ctgcaaaaag
     5701 ccaacgttct ggggcagaag ctgaaagacg gattgctggc gatagccgaa aaacacccgg
     5761 agatcggcga cgtacgcggt ctgggggcga tgatcgccat cgagctgttt gaagatggcg
     5821 atcacagcaa accggacgca aaactcaccg ccgagatcgt ggcacgcgcc cgcgataagg
     5881 gtctgattct tctctcctgc ggcccgtatt acaacgtgct gcgcatcctt gtaccgctca
     5941 ccattgaaga cgctcagatc cgtcagggtc tggagatcat cagccagtgt tttgctgagg
     6001 cgaagctgta gcaccgcacc atgccggagg cgacgctttg cggcttgtcc ggcctacgag
     6061 aatccaggtc ggataaggcg tttacgccgc atccgacaat ctgtacgtga acaggaataa
     6121 atctatgtcg gccggataag gcggagccgc tctccggcaa aaagaaccaa taacaattaa
     6181 acgcgtgacc cgacgcggga aatgtcgggg cgctctccca agtgacacac tttcgagagg
     6241 attcaggatg gggcaatcat cgcaaccaca tgagttaggc ggcgggctga agtcacgcca
     6301 cgtcaccatg ttgtctattg ccggtgttat cggcgcaagt ctgtttgtcg gttccagcgt
     6361 cgccatcgcc gaagcgggcc cggcggtatt actggcctat ctgttcgccg gattactggt
     6421 ggttatgatt atgcggatgt tggcggaaat ggcggttgcc acgcccgata ccggttcgtt
     6481 ttccacctat gccgataaag ccattggccg ctgggcgggc tataccatcg gctggttgta
     6541 ctggtggttt tgggtactgg ttatcccact tgaagccaac atcgccgcca tgatcctgca
     6601 ctcatgggtt ccaggcattc ccatctggtt attttccctc gtcattaccc tcgccttaac
     6661 cggcagtaat ttattaagcg ttaaaaacta cggcgaattt gagttctggc tggcgctgtg
     6721 taaagtcatc gctatcctgg cctttatttt ccttggtgcc gtcgcaatta gcggttttta
     6781 cccgtatgcc gacgtgagcg ggatttcaag attgtgggat agcggcggct ttatgcccaa
     6841 cggcttcggt gcggtattaa gcgcgatgtt gatcaccatg ttctcgttta tgggcgcaga
     6901 aattgtcacc attgccgccg cggaatccga cacgccggaa aaacatattg ttcgcgccac
     6961 caactcggtt atctggcgta tctctatttt ctatttgtgt tctatttttg tcgttgttgc
     7021 attaatcccg tggaatatgc cagggctgaa agccgttggt tcttatcgct cggttctgga
     7081 attgctcaat attcctcatg cgaaattaat catggactgc gtgatattac tttccgtaac
     7141 cagttgcctg aactcggcgc tgtataccgc ttccaggatg ctctactcct taagccgtcg
     7201 cggtgatgct cccgcggtaa tgggtaaaat caaccgcagt aaaaccccgt acgtagcggt
     7261 gttactctcc accagcgcgg cattcttaac ggtggtggtg aactattacg cgcctgcgaa
     7321 ggtgtttaaa tttctgatcg acagctccgg cgctatcgcc ctgctggttt atttagtcat
     7381 cgccgtttca caattgcgga tgcgcaaaat tctgcgagca gaaggaagcg aaattcgcct
     7441 gcggatgtgg ctttatccgt ggctcacctg gctggtcatc ggctttatta cctttgtgtt
     7501 ggtagtgatg ctattccgcc cggcgcaaca gttagaagtg atctccaccg gcttattagc
     7561 gattgggatt atctgtaccg tgccaattat ggctcgctgg aaaaagctga taatgtggca
     7621 aaaaacaccc attcataata cgcgctgata atgatcagga gtcacaccat gaccattacc
     7681 tctctggatg gctatcgctg gctgaagaac gatattattc gcggcaattt tcagccggat
     7741 gaaaaattac ggatgagttt gctgacatcg cgttatgcac ttggcgttgg gccgttgcgg
     7801 gaagcacttt cgcaactggt ggcagaacga ctggtcacgg tggtgaatca aaaagggtat
     7861 cgggtggcgt ctatgtcaga gcaggagctg ctcgatattt tcgacgcccg cgccaatatg
     7921 gaagcgatgc tggtgagtct ggcgattgcc cgcggtggcg atgaatggga ggcagacgtt
     7981 ctcgcaaaag cgcatctgct cagtaagctt gaggcctgtg acgccagtga gaaaatgctt
     8041 gatgagtggg atctgcgtca tcaggcgttt catactgcaa ttgtggcggg ctgtggttct
     8101 tactatttgc tgcaaatgcg tgaacggttg tttgatctgg cagcgcgtta tcgatttatc
     8161 tggctgcggc gaacagtgct ttcggtggaa atgctggaag ataaacacga tcagcaccag
     8221 accctgactg cggcggtact ggcgcgagat accgcgcgcg ccagtgagtt aatgcgccag
     8281 catttactga cgccaattcc cattatccag caggcgatgg ctggcaatta actactcttc
     8341 aggaatacgc aacacttgcc ccgggtaaat tttatccggg ctttttagca tcggtttatt
     8401 cgcttcgaag attttattgt acagattagc gttaccgtag acctgtttgg aaatggcact
     8461 cagagtgtcg ccagacttaa cggtataaaa ctggctggca gtggctggtg tcgccgtttt
     8521 cacctgatca tcgacactgg caataccgga aatattcccc accgcaacaa ggattttctc
     8581 cttcgcctcc tgacttaagc cgtcaccagt gaccgtcgct ttgccgtcgg caatttgaat
     8641 gttcacttta tcggcatcag gtataccggt tttgttcaga tgctcctgca ccttcttcgc
     8701 ctgatcgtct ttatcgtgct gacctgtaac cgcgtcccag agtttttctc cggcatcttt
     8761 cacaaaattg aacagaccca tagctacctc attcgttaac ggaaacactc agaaagtgta
     8821 gcagaggaac gcggcgcgtt aacgccgcgg gggtgagcac aggtttaatc gcgggtttgc
     8881 acccagaacg cgtgaatcaa accggggata tagccaagca gtgtcagcag aatattaata
     8941 atgaacgccc aaccgaaccc tttaccgagc agcacgccga gcggcggcag aatgatggtg
     9001 atgacgattc tccagaaacc catatgtact ccctataaga aaattactca ttgtttaaaa
     9061 agagatttta tctcttaagc gtagtaattt tagcggagcc tgccagtttc agcgtacgct
     9121 tttactctca tttacgctgc tgatgctggt atatgttgca cacttagttt agagtttact
     9181 taatttagaa aatacttaaa caactatgac tgaactcgca caattacagg ccagtgccga
     9241 acaggcagcg gccttattga aatcaatgag ccaccctaaa cgattgctga ttctgtgtat
     9301 gcttagcggt tcccccggca ccagcgcggg agagctgacg cgcattaccg gactgagtgc
     9361 ctctgcgaca tcacagcatc tcgctcgtat gcggggcgaa gggcttatcg actgccaacg
     9421 ggatgcccaa cgcattctat attccattaa aaatgaggcg gtaaatgcca ttatcgccac
     9481 cctgaaaaat gtctattgtc cgtaaggagt cactatggct ttgacaacca tttcgccgca
     9541 tgatgcacaa gaattaatcg cacgcggcgc aaagttaatc gatattcgtg atgctgatga
     9601 atatcttcgt gaacatattc ctgaagcaga tctggctcca ttatccgtac tggaacagtc
     9661 aggtcttccg cctaaattac gtcgcgagca aattatattc cactgccagg caggtaaacg
     9721 caccagtaat aacgctgata aattagcagc gattgccgcc cccgcagaaa tctttttact
     9781 cgaagatggg attgatggct ggaaaaaagc aggattgcca gtagcggtaa ataaatccca
     9841 acccttaccg ttaatgcgcc aggtgcaaat cgccgcgggt ggtttaatat taatcggcgt
     9901 tgtactgggt tataccgtaa atagcgtttt cttcttatta agcggctttg ttggtgctgg
     9961 gttactgctt gcaggaatta gtggtttttg tggaatggca aggttgttag ataagatgcc
    10021 gtggaaccaa cgagcttgag cagcgacgcc ggacgcgcca tagcagcgac atccggcctc
    10081 agtaattaga tcaggaaatc gtcgagagat ttaccttctg ccagcgcctg agcgattggc
    10141 ttcggtgtac ggccctgacc ggtccaggtt ttagtttcac cgttaacatc gatgaattta
    10201 tatttcgccg gacgcggctg gcgtttttta ccagcgcgtg gtgccgcagc agagctatta
    10261 cccaataact cttccgggtt aattccgtca gctttcatca gctccagcca ggtgctaatt
    10321 ttttcctggc gctctgccag ttcacgctgc tgttgttctt cttcttcacg tctttcttta
    10381 gtgacaaccc tgaatttttc gagcatttct tcaagaacgt caatggagaa ttcgcgagcc
    10441 atcgcacgga gggtgcgaat gttatttaaa ctttgtaaca ttacggacat aataaagaaa
    10501 accttttaac gccaaaacaa aaaagtattt cgtcgcgtag tgtaagcgat cacttattat
    10561 atttc
//
LOCUS       DAFGPF010000152        10549 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFGPF010000152 DAFGPF010000000
VERSION     DAFGPF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10549
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.152"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..113)
                     /locus_tag="LSX49_004559"
     CDS             complement(<1..113)
                     /locus_tag="LSX49_004559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBL7170859.1"
                     /translation="MEVVAEGVETPDCLAWLRQAGCDTVQGFLFARPMPAAA"
     gene            complement(316..1329)
                     /gene="intI1"
                     /locus_tag="LSX49_004560"
     CDS             complement(316..1329)
                     /gene="intI1"
                     /locus_tag="LSX49_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="HBL7170860.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     gene            1487..1960
                     /locus_tag="LSX49_004561"
     CDS             1487..1960
                     /locus_tag="LSX49_004561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HBL7170861.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
     gene            2091..2879
                     /locus_tag="LSX49_004562"
     CDS             2091..2879
                     /locus_tag="LSX49_004562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HBL7170862.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
     gene            3085..3432
                     /locus_tag="LSX49_004563"
     CDS             3085..3432
                     /locus_tag="LSX49_004563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HBL7170863.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     gene            3426..4265
                     /gene="sul1"
                     /locus_tag="LSX49_004564"
     CDS             3426..4265
                     /gene="sul1"
                     /locus_tag="LSX49_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /protein_id="HBL7170864.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     gene            4393..4596
                     /locus_tag="LSX49_004565"
     CDS             4393..4596
                     /locus_tag="LSX49_004565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170865.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLGIASENGK"
     gene            4752..5957
                     /gene="chrA"
                     /locus_tag="LSX49_004566"
     CDS             4752..5957
                     /gene="chrA"
                     /locus_tag="LSX49_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate efflux transporter"
                     /protein_id="HBL7170866.1"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRR
                     RWLSERSYADLVALCQFLPGPASSQVGIAVGLSRAGYSGALAAWAGFTLPSAIALILF
                     ALGISSYGDYVSQGALHGLKVVAVAVVAQAVWGMARNLCTDGLRVTIMAIATCVVLLV
                     PSAWGQVGVIAIAGIAGRLLFKPAKVVEHDPLPITVSHRAGVLWLSLFFVLLIGLPVL
                     AELMPSQTMAMVDSFYRVGSLVFGGGHVVLPLLQAEVVPSGWVNNESFLAGYGAAQAV
                     PGPLFTFAAFLGASMNTAPSGWIGGIVCLLAIFAPSFLLVVGSMPFWERLRRNTGIQA
                     ALAGINAAVVGLLLAALYQPVWTSAIFQPQDFGLALVALVALMFWKLPPWLVVLGSGA
                     AGWLLSVAL"
     gene            5968..6273
                     /locus_tag="LSX49_004567"
     CDS             5968..6273
                     /locus_tag="LSX49_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7170867.1"
                     /translation="MTDKDLYGGLIRLHILHHAAEEPVFGLGIIEELRRHGYEMSAGT
                     VYPMLHGLEKKGYLTSRHERTGRRERRVYDITEQGRTALADAKTKVKELFGELVEGG"
     gene            6317..6382
                     /locus_tag="LSX49_004568"
                     /pseudo
     CDS             6317..6382
                     /locus_tag="LSX49_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            6500..7264
                     /locus_tag="LSX49_004569"
     CDS             6500..7264
                     /locus_tag="LSX49_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="HBL7170868.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDH
                     TTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTID
                     FYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETA
                     HRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQ
                     PGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
     gene            complement(7757..8341)
                     /locus_tag="LSX49_004570"
     CDS             complement(7757..8341)
                     /locus_tag="LSX49_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7170869.1"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAAL
                     IQRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVN
                     YLISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVD
                     PDGELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
     gene            complement(8341..9579)
                     /locus_tag="LSX49_004571"
     CDS             complement(8341..9579)
                     /locus_tag="LSX49_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170870.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWA
                     GATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTG
                     LIACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGA
                     AIGLLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLL
                     RPLFGIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVG
                     ARISAQNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRT
                     PPELLGRVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQ
                     FATMAAAATASAPTHTEGEH"
     gene            complement(9576..10481)
                     /locus_tag="LSX49_004572"
     CDS             complement(9576..10481)
                     /locus_tag="LSX49_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HBL7170871.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
BASE COUNT         2184 a         3057 c         3127 g         2181 t
ORIGIN      
        1 gccgccgccg gcatcggcct ggcgaacagg aaaccctgca ccgtgtcgca acccgcctgc
       61 cgcaaccacg caaggcagtc gggtgtttcc acaccctcgg ctaccacctc cattgtcgtt
      121 ttcagaagac ggctgcactg aacgtcagaa gccgactgca ctatagcagc ggaggggttg
      181 gatccatcag gcaacgacgg gctgctgccg gccatcagcg gacgcaggga ggactttccg
      241 caaccggccg ttcgatgcgg caccgatggc cttcgcgcag gggtagtgaa tccgccagga
      301 ttgacttgcg ctgccctacc tctcactagt gaggggcggc agcgcatcaa gcggtgagcg
      361 cactccggca ccgccaactt tcagcacatg cgtgtaaatc atcgtcgtag agacgtcgga
      421 atggccgagc agatcctgca cggttcgaat gtcgtaaccg ctgcggagca aggccgtcgc
      481 gaacgagtgg cggagggtgt gcggtgtggc gggcttcgtg atgcctgctt gttctacggc
      541 acgtttgaag gcgcgctgaa aggtctggtc atacatgtga tggcgacgca cgacaccgct
      601 ccgtggatcg gtcgaatgcg tgtgctgcgc aaaaacccag aaccacggcc aggaatgccc
      661 ggcgcgcgga tacttccgct caagggcgtc gggaagcgca acgccgctgc ggccctcggc
      721 ctggtccttc agccaccatg cccgtgcacg cgacagctgc tcgcgcaggc tgggtgccaa
      781 gctctcgggt aacatcaagg cccgatcctt ggagcccttg ccctcccgca cgatgatcgt
      841 gccgtgatcg aaatccagat ccttgacccg cagttgcaaa ccctcactga tccgcatgcc
      901 cgttccatac agaagctggg cgaacaaacg atgctcgcct tccagaaaac cgaggatgcg
      961 aaccacttca tccggggtca gcaccaccgg caagcgccgc gacggccgag gtcttccgat
     1021 ctcctgaagc cagggcagat ccgtgcacag caccttgccg tagaagaaca gcaaggccgc
     1081 caatgcctga cgatgcgtgg agaccgaaac cttgcgctcg ttcgccagcc aggacagaaa
     1141 tgcctcgact tcgctgctgc ccaaggttgc cgggtgacgc acaccgtgga aacggatgaa
     1201 ggcacgaacc cagtggacat aagcctgttc ggttcgtaaa ctgtaatgca agtagcgtat
     1261 gcgctcacgc aactggtcca gaaccttgac cgaacgcagc ggtggtaacg gcgcagtggc
     1321 ggttttcatg gcttgttatg actgtttttt tgtacagtct atgcctcggg catccaagca
     1381 gcaagcgcgt tacgccgtgg gtcgatgttt gatgttatgg agcagcaacg atgttacgca
     1441 gcagggcagt cgccctaaaa caaagttagc cattaaggga gttaaattga aaatatcatt
     1501 gatttctgca gtgtcagaaa atggcgtaat cggtagtggt cctgatatcc cgtggtcagt
     1561 aaaaggtgag caactactct ttaaagcgct cacatataat caatggctcc ttgtcggaag
     1621 aaaaacattt gactctatgg gtgttcttcc aaatcgcaaa tatgcagtag tgtcaaagaa
     1681 cggaatttca agctcaaatg aaaacgtcct agtttttcct tcaatagaaa atgctttgaa
     1741 agagctatca aaagttacag atcatgtata tgtctctggc gggggtcaaa tctataatag
     1801 ccttattgaa aaagcagata taattcattt gtctactgtt cacgttgaag tcgaaggtga
     1861 tatcaaattc cctataatgc ctgagaattt caatttggtt tttgaacagt tttttatgtc
     1921 taatataaat tatacatacc agatttggaa aaaaggctaa caatgcgttg cagcaccagt
     1981 cgcttcgctc cttggacagc ttttaagtcg cgtctttgtg gttttgctgc gcaaaagtat
     2041 tccacaaagc cgcaacttaa aagctgccgc tgaacttaac gttaggcatc atgggtgaat
     2101 ttttccctgc acaagttttc aagcagctgt cccacgctcg cgcggtgatc gagcgccatc
     2161 tggctgcgac actggacaca atccacctgt tcggatctgc gatcgatgga gggctgaagc
     2221 cggacagcga catagacttg ctcgtgaccg tcagcgccgc acctaacgat tcgctccggc
     2281 aggcgctaat gctcgatttg ctgaaagtct catcaccgcc aggcgatggc ggaacatggc
     2341 gaccgctgga gctaactgtt gtcgctcgaa gcgaagtagt gccttggcgc tatccggcgc
     2401 ggcgtgagct tcagttcggt gagtggctcc gccacgacat cctttccgga acgttcgagc
     2461 ctgccgttct ggatcacgat cttgcgattt tgctgaccaa ggcgaggcaa cacagccttg
     2521 cgcttctagg cccatccgca gccacgtttt tcgagccggt gccgaaggag catttctcca
     2581 aggcgctttt cgacactatt gcccagtgga atgcagagtc ggattggaag ggtgacgagc
     2641 ggaacgtcgt tcttgctctt gctcgcattt ggtacagcgc ttcaactggt ctcattgctc
     2701 ctaaggacgt tgctgccgca tgggtatcgg agcgtttgcc tgccgagcat cggcccctca
     2761 tctgcaaggc acgcgcggcg tacctgggta gcgaggacga cgacctagca atgcgcgtcg
     2821 aagagacggc cgcgttcgtt cgatatgcca aagcaacgat tgagagaatc ttgcgttgag
     2881 cggcatgtgc gaaaagtgca tcgacccgcg ccgagggcat ctgatgccta actcggcgtt
     2941 caagcggacg ggctgcgccc gccgctcaac tatgcgttag atgcactaag cacataattg
     3001 ctcacagcca aactatcagg tcaagtctgc ttttattatt tttaagcgtg cataataagc
     3061 cctacacaaa ttgggagata tatcatgaaa ggctggcttt ttcttgttat cgcaatagtt
     3121 ggcgaagtaa tcgcaacatc cgcattaaaa tctagcgagg gctttactaa gcttgcccct
     3181 tccgccgttg tcataatcgg ttatggcatc gcattttatt ttctttctct ggttctgaaa
     3241 tccatccctg tcggtgttgc ttatgcagtc tggtcgggac tcggcgtcgt cataattaca
     3301 gccattgcct ggttgcttca tgggcaaaag cttgatgcgt ggggctttgt aggtatgggg
     3361 ctcataattg ctgccttttt gctcgcccga tccccatcgt ggaagtcgct gcggaggccg
     3421 acgccatggt gacggtgttc ggcattctga atctcaccga ggactccttc ttcgatgaga
     3481 gccggcggct agaccccgcc ggcgctgtca ccgcggcgat cgaaatgctg cgagtcggat
     3541 cagacgtcgt ggatgtcgga ccggccgcca gccatccgga cgcgaggcct gtatcgccgg
     3601 ccgatgagat cagacgtatt gcgccgctct tagacgccct gtccgatcag atgcaccgtg
     3661 tttcaatcga cagcttccaa ccggaaaccc agcgctatgc gctcaagcgc ggcgtgggct
     3721 acctgaacga tatccaagga tttcctgacc ctgcgctcta tcccgatatt gctgaggcgg
     3781 actgcaggct ggtggttatg cactcagcgc agcgggatgg catcgccacc cgcaccggtc
     3841 accttcgacc cgaagacgcg ctcgacgaga ttgtgcggtt cttcgaggcg cgggtttccg
     3901 ccttgcgacg gagcggggtc gctgccgacc ggctcatcct cgatccgggg atgggatttt
     3961 tcttgagccc cgcaccggaa acatcgctgc acgtgctgtc gaaccttcaa aagctgaagt
     4021 cggcgttggg gcttccgcta ttggtctcgg tgtcgcggaa atccttcttg ggcgccaccg
     4081 ttggccttcc tgtaaaggat ctgggtccag cgagccttgc ggcggaactt cacgcgatcg
     4141 gcaatggcgc tgactacgtc cgcacccacg cgcctggaga tctgcgaagc gcaatcacct
     4201 tctcggaaac cctcgcgaaa tttcgcagtc gcgacgccag agaccgaggg ttagatcatg
     4261 cctagcattc accttccggc cgcccgctag cggaccctgg tcaggttccg cgaaggtggg
     4321 cgcagacatg ctgggctcgt caggatcaaa ctgcactatg aggcggcggt tcataccgcg
     4381 ccaggggagc gaatggacag cgaggagcct ccgaacgttc gggtcgcctg ctcgggtgat
     4441 atcgacgagg ttgtgcggct gatgcacgac gctgcggcgt ggatgtccgc caagggaacg
     4501 cccgcctggg acgtcgcgcg gatcgaccgg acattcgcgg agaccttcgt cctgagatcc
     4561 gagctcctag ggatcgcctc agaaaacgga aaataaagca cgctaagccg taagtaagcg
     4621 tgctcctgtg aaagccacag ctaaaactgc gtagtacaca tagaggtatt tttttctaga
     4681 tttatatcga atttcgttat cgaatttcgc ttattattga tcaactcgtt gcagatcatg
     4741 aaggcgaaag tatgacgaat aaccctaccg atgacagcag accatggtcg gtctttctta
     4801 tttttctgcg gcttggattg acatcttttg gcggccccat tgcgcacttg ggctacttcc
     4861 gcgccgaatt tgtcacacgg cggcgctggc tctccgaacg gagctatgct gacttggtcg
     4921 cgctttgtca gttcttgcca gggcctgcaa gcagccaggt cggcatagcg gtaggactgt
     4981 ctcgggctgg atacagcggg gcgctggctg cttgggctgg cttcacgctg ccgtctgcca
     5041 tagccttgat cctttttgcg ctcggcatct ccagctatgg cgattacgtc tcgcagggcg
     5101 cgttgcatgg cttaaaagtg gtggctgtgg ccgtggtcgc tcaagcagta tggggcatgg
     5161 cgcgtaacct atgcacggat gggctgcgag tcaccatcat ggcaattgct acctgcgtcg
     5221 ttttacttgt gccgtccgcg tggggacagg ttggcgtgat tgctatcgca ggcatcgcag
     5281 gccggttatt gttcaagcca gcgaaagttg ttgagcatga ccccctacct atcacggtca
     5341 gtcaccgggc cggcgtgctt tggctctcgc tgttctttgt cttgctgatt ggcctgccgg
     5401 tgttggccga actgatgcca agtcaaacca tggcaatggt ggattccttc tatcgtgtcg
     5461 gatcactggt gttcggcggt ggtcacgttg tgctgccatt actgcaagcc gaagtggtgc
     5521 cctccggctg ggtcaacaat gaatcctttc tcgcggggta cggggcagct caagcggtgc
     5581 ccggcccttt gttcacgttc gccgcgtttc ttggtgcctc gatgaacacc gccccgtcgg
     5641 gctggatcgg cggcattgtg tgtctgctgg ctatcttcgc gccctcgttc ttgctggtcg
     5701 tcggatcaat gccattttgg gagcgtttgc gccgcaatac aggcatccaa gctgcgctgg
     5761 ccgggatcaa tgccgctgta gtcggcttgc tgctggccgc gctgtatcag cctgtatgga
     5821 ctagcgccat ctttcagccg caagacttcg gcttggcatt agttgccctt gtcgcactta
     5881 tgttctggaa gctcccgccg tggctggttg tcctcggtag cggtgcagct gggtggctgt
     5941 tgagcgtcgc tctgtgaggc acaaaaaatg actgacaaag acctctacgg cggtttgatc
     6001 cgcctgcaca tccttcacca tgcagccgag gaacctgtct ttgggctggg gatcatcgaa
     6061 gagctacgcc gacacggcta cgagatgagc gctggcaccg tgtacccgat gctgcacggc
     6121 ctggaaaaaa aaggctatct gacctcacgc cacgaacgca ccgggcgacg tgaacggcgt
     6181 gtttatgaca tcactgaaca aggcagaact gcacttgctg atgcgaaaac aaaggtcaag
     6241 gagctgttcg gagagttggt agaaggtggt tgagtttttg cttctatgtc aggttgagct
     6301 ataccctaac tggattgtca ttttcagaag acgactgcac cagttgattg ggcgtaatgg
     6361 ctgttgtgca gccagctcct gacagttcaa tatcagaagt gatctgcacc aatctcgact
     6421 atgctcaata ctcgtgtggg ctctgttgca aaaatcgtga agcttgagca tgcttggcgg
     6481 agattggacg gacggaacga tgacggattt caagtggcgc catttccagg gtgatgtgat
     6541 cctgtgggcg gtgcgctggt attgtcgcta tccgatcagc tatcgcgacc ttgaggaaat
     6601 gctggcggaa cgcggcattt cggtcgacca tacgacgatc tatcgctggg tccagtgcta
     6661 cgccccggag atggagaagc ggctgcgctg gttctggcgg cgtggctttg atccgagctg
     6721 gcgcctggat gaaacctacg tcaaggtgcg gggcaagtgg acctacctgt accgggcagt
     6781 cgacaagcgg ggcgacacga tcgatttcta cctgtcgccg acccgcagcg ccaaggcagc
     6841 gaagcggttc ctgggcaagg ccctgcgagg cctgaagcac tgggaaaagc ctgccacgct
     6901 caataccgac aaagcgccga gctatggtgc agcgatcacc gaattgaagc gcgaaggaaa
     6961 gctggaccgg gagacggccc accggcaggt gaagtatctc aataacgtga tcgaggccga
     7021 tcacggaaag ctcaagatac tgatcaagcc ggtgcgcggt ttcaaatcga tccccacggc
     7081 ctatgccacg atcaagggat tcgaagtcat gcgagccctg cgcaaaggac aggctcgccc
     7141 ctggtgcctg cagcccggca tcaggggcga ggtgcgcctt gtggagagag cttttggcat
     7201 tgggccctcg gcgctgacgg aggccatggg catgctcaac caccatttcg cagcagccgc
     7261 ctgatcggcg cagagcgaca gcctacctct gactgccgcc aatctttgca acagagcccg
     7321 ccgtgctagt ctgctcggtg atggtggagt gaagccaacc cgcaatcggg ttatgaatct
     7381 gcatcgcgat tcgcaatcag ctgtctcttg agcatgtcga actcctgcga tgttatctcg
     7441 ccgtgctcgt gctgctacac caacttgtcc aactcatccg ccacaccgct ccccaccacc
     7501 tgcgatggcc aggttgtttg ctgggcgcat tggcggagta tcgtctcgac ccgggacacc
     7561 cacaccggca caaccttacg ggagtgattc actgtcaaag aatcggcccg gtgctctgac
     7621 gcaagtatcg ggatggtcac catttgtaag ccgtagacct gagtggtgat caagacttcg
     7681 ataccaccga ccgtaccggt actaatcgac gacggtcgtg ttcgtcgcct gccgcaggga
     7741 ctctgcacac ctccgtttac gcatgtgcct ggaggagttg gaaatcgtcg tgttcgggaa
     7801 acattaaaca caggatggca gcgatctgag ccagcacatg atcagctagc tcaccatccg
     7861 gatcgacggc ccactgcatc gtcgcgccag cgatgaccga gtgcaggagc aactcagctg
     7921 ccgcaggagc acctgggggc agtcgcttgc ggatcccctc caccaccgcg cggttccgct
     7981 ggatcgcaag cgtgcgtagc tccggcacct ggagctcgta ccaggagatg agatagttca
     8041 ccgagaagtc gttgcgagtg ttcatgctcc gaacgagcac ctgcaaaaat tcccagagcc
     8101 cttgcggccc tgcgcctatc ggtatcgcat tcaggtaatg ccgcacctgc tcgacgccgc
     8161 gctccatcat cctcaccagc agcgtatcgc ggttggtgaa gcgctggatt aacgctgcgc
     8221 gggagagccc cacctccttt gctactccgc tgagcgtgaa ctctatggga ccgcaacgct
     8281 tcagcactac ggtggcggcc tcgagtacct cgtcatcgga cttgagcttg gggcggggca
     8341 tcagtgttca ccttctgtat gggttggggc ggaggctgtg gctgccgccg ccattgtagc
     8401 aaattgaaga cggagcgaga gtagagccac gagccccgca aacacggccg atacaacgag
     8461 gccagggagc ggaccagcaa ggtcgacaaa cgcgccggcc gcaagcataa ccatgggcga
     8521 ggctgacagc atcaccgccg agaccgtgcc gagtacccgg ccgagaagtt ctggcggcgt
     8581 gcggttgtag atggcagcgt tgagaatggg agagactgag ccggtcagca gtcccacgag
     8641 cgcgcccaac aacatcagca ccggcacgcc tggcaactgt gaaagcagaa gcgagcccac
     8701 cgcagagcca caaaatgcca ccgccagcca gttctgcgct gatatccggg cgccgaccga
     8761 cgcatgaatg gcaatgccaa ggagaccacc agcccccatc attgaggaga acagcccgag
     8821 ctctgctact tggcgtcctg catctacaaa cagcgcaggc atgatgacgc tgccgttggc
     8881 gccaacgatg cccacgaaga tcatcactat accaaagaga gggcgcagca ggggttcgct
     8941 ccagagaaaa gcgacgccgg cgcgcatgga gagagtcgcc gtcgtggtca tcgtccgagc
     9001 ggcacgcgcg ggaagcaccc acgcgccgag cagacctgca aggacggagc agaacgccgt
     9061 cagcccgagc gttggcgcag cgccaagcag gccgattgcg gcccccccaa gggccgggcc
     9121 acctagaatc gcgacgttcc cgatcaccgc tttcagtgac gagacgcgct caacggagag
     9181 cccggcgacg tggccgagtt tgggcagctc actgtcctgc gcggccatac cgggtgcgtc
     9241 gaacgcggca ccgagcacca cgcaagcgat cagcccagtg ttcgagaggg cgccaacggc
     9301 atcgagcagt gggatgctcg ccatggccac gccgcccacc acacccgaga tcaatgcgac
     9361 gggcgcgcgc ccgaaccgat cgacgaggcc accaccaacc cacgcgccga tgatggtcgc
     9421 gatgacgctg ctagcggccg tggcgcccgc ccaggccgcg ctctttgtat gagacaggac
     9481 gaaccatgga agcgcgaggg ccgccaccgc gttgccgatc cggaagagaa aggtcgccgc
     9541 gaacagcgtc gcgagcgggc tatatcgacg ttcgctcatt ccgctgcggc gagctgcgcc
     9601 ttcgccgcag cgaggtactc ttcgttaccc gagtcgaggg cgaagagtgc gtaggtgacc
     9661 gccccgaacg caaggcgctc cgcgatgtgg tgggcgagcc gcggccacac ccggccaccg
     9721 gccgcttcat acgtgaggag gagcttcgcg agcccctctt caccaaagac cataaggtgc
     9781 gcggccatgt cgatggcagg gtcatcaacg cgggcctcgc tccagtcgat catcccgctg
     9841 acgcgctccg tgttgtcgat gagcacatgg cccacgtaga gatcgccatg caccaccacg
     9901 gagaaatctg gccacgacga atcgtcgtcg agccagcgct gccaccggtg gaggcgcttg
     9961 tcgttcacca cgaactcgcg tcggacgcgg tcaacgtcgt cggccacctt ctgacgggcc
    10021 tgcgtcggtg tacggatgag catccccgca tccacggcgg cggaaatggg gacggcatgc
    10081 agggcggcga gcgcggtcgc gaagctctcc gcgaagacct ccgagtcctg cggcacgacc
    10141 cagtcgggcg tggacgaacc aggctggatg accatcgcag tcgagtcttc gagcatggga
    10201 taggcaacga gctcggcgtt ggccacgcgc cagtccggca ccgcgaacgg caggcgattc
    10261 ttgagcattg ccagcacccg cgcctctggt tcgaccttcg cgcttacctc ggctcggcgc
    10321 gggatgcgca gcacccaccg acgtccatcg tcgacggtgg cgatcacgat cctatagtcg
    10381 agcccaagct cattgacagt cagcgggcca tggagcttga gcccatgtcg ggctgcaagt
    10441 gcgtacagtt gggaggtatc ggcggtcgtg actacggtca tgattcactc ctgagggctt
    10501 gacgggttta gccacctaaa tgtaacagtc acgtcggtta tattcaatc
//
LOCUS       DAFGPF010000153        10533 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFGPF010000153 DAFGPF010000000
VERSION     DAFGPF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10533
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.153"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..747
                     /locus_tag="LSX49_004573"
     CDS             <1..747
                     /locus_tag="LSX49_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7170872.1"
                     /translation="LARTNRSVLLTEAGKQFLVDSRQILSMVDDAAARAERLHQGEAG
                     ELRIGFTSSAPFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRN
                     TALPETLEHAVIVHEPLMAMIPHDHPLANNPSVTLAELAKEPFVFFDPHVGTGLYDDI
                     LGLMRRYNLTPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDA
                     VSEMWLVWPKHHEQSPAARNFRIHLLNALR"
     gene            882..2102
                     /gene="mlc"
                     /locus_tag="LSX49_004574"
                     /gene_synonym="dgsA"
     CDS             882..2102
                     /gene="mlc"
                     /locus_tag="LSX49_004574"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor Mlc"
                     /protein_id="HBL7170873.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEESQELALKDDSPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            2227..2922
                     /gene="bioD"
                     /locus_tag="LSX49_004575"
     CDS             2227..2922
                     /gene="bioD"
                     /locus_tag="LSX49_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HBL7170874.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TDKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(2875..4167)
                     /gene="clcB"
                     /locus_tag="LSX49_004576"
     CDS             complement(2875..4167)
                     /gene="clcB"
                     /locus_tag="LSX49_004576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HBL7170875.1"
                     /translation="MHHLHIYPDLRTMFRRLLIATIVGILAAFAVAGFRHAMLLLEWL
                     FLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQ
                     TDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWI
                     ACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDAL
                     LYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGG
                     LIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVF
                     TPTLFIGLAIGMLYGRSLGLWLPDGEEITLLLGLTGMATLLAATTHAPTMSTLMICEM
                     TGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS"
     gene            complement(4328..4942)
                     /gene="dmsD"
                     /locus_tag="LSX49_004577"
     CDS             complement(4328..4942)
                     /gene="dmsD"
                     /locus_tag="LSX49_004577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HBL7170876.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTNDGWET
                     QWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMKQNEPEDNFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR"
     gene            complement(4985..5839)
                     /locus_tag="LSX49_004578"
     CDS             complement(4985..5839)
                     /locus_tag="LSX49_004578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HBL7170877.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQHII
                     RGMFFLWLLMGIGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLVSMALGIIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAATILRAARVTFNTTPFAIISILALIACAGLIVLQGLSLASIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLVLGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            complement(5841..6458)
                     /gene="dmsB"
                     /locus_tag="LSX49_004579"
     CDS             complement(5841..6458)
                     /gene="dmsB"
                     /locus_tag="LSX49_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HBL7170878.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            complement(6469..8038)
                     /locus_tag="LSX49_004580"
                     /pseudo
     CDS             complement(6469..8038)
                     /locus_tag="LSX49_004580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
     gene            complement(8099..10525)
                     /locus_tag="LSX49_004581"
     CDS             complement(8099..10525)
                     /locus_tag="LSX49_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HBL7170879.1"
                     /translation="MSKNEQMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRSAAAAV
                     QQASEKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDKYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGE
                     GDDKTAKTPQWASQITGIPVDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSKLAEIARTWELEKDEVISPLPVYASTFEGWDSPER
                     STFPLQLFGFHYKSRTHSTYGNIDVLKAACRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
BASE COUNT         2592 a         2671 c         2705 g         2565 t
ORIGIN      
        1 ctggcacgga ccaatcgcag tgtattgctg acggaagcag gaaaacagtt tcttgtagat
       61 agtcggcaaa tcctgtctat ggtggatgat gctgccgctc gcgctgaaag gctgcatcag
      121 ggcgaagcgg gggagttgcg cattggtttt acttcgtccg ctccttttat tcgggcggtg
      181 tccgatacgt tatcgctgtt tcgccgtgat tatcccgatg tccatttaca aacccgcgaa
      241 atgaacactc gcgagcaaat cgctccgctc attgaaggaa cgctggatat gggattgctg
      301 cgtaacacag cgttaccgga gacgcttgaa cacgcagtca tcgtccatga accgcttatg
      361 gcgatgatcc cgcacgatca tcccctggca aataacccga gtgtaacgct ggctgaactg
      421 gcgaaagaac cctttgtctt ttttgatccg cacgtcggaa cagggctgta tgacgatatt
      481 ctcgggctga tgagacgtta caatttgacg cccgtcatca ctcaggaggt gggtgaggca
      541 atgaccatca tcggtctggt ttccgctggt ctgggtgttt caattttgcc tgcgtcattt
      601 aaacgtgttc agctcaacga aatgcgctgg gtgccgattg ctgaagagga tgcggtttct
      661 gaaatgtggt tggtctggcc gaaacatcat gaacaaagtc cggctgcgcg taactttcgt
      721 attcatctgc tgaatgctct caggtgaggg aaatttcagc gaaaaagccc gaaaaatgtg
      781 ctgttaatca catgcctaag taaaaatttg acgacacgta ttgaagtgct tcaccatagc
      841 ctacagatta tttcggagcg cgaaaatata gggagtatgc ggtggttgct gaaaaccagc
      901 ctgggcacat tgatcaaata aagcaaacca acgcgggcgc agtttatcgc ctgattgatc
      961 agcttggtcc agtctcgcgt atcgatcttt cccgtctggc gcaactggct cctgccagta
     1021 tcactaaaat tgtccgtgag atgctcgaag cacacctggt gcaagagctg gaaatcaaag
     1081 aagcggggaa ccgtggccgt ccggcagtgg ggctggtggt tgaaactgaa gcctggcact
     1141 atctttctct gcgcattagt cgcggggaga ttttccttgc tttgcgcgat ctgagcagca
     1201 aactggtagt ggaggagtcg caggaactgg cgttaaaaga tgactcgcca ttgctggatc
     1261 gtatcatttc ccatatcgat cagtttttta tccgccacca gaaaaaactt gagcgtctga
     1321 cttcgattgc cataaccttg ccgggaatta ttgatacgga aaatggtatt gtacatcgca
     1381 tgccgttcta cgaggatgta aaagagatgc cgctcggcga ggcgctggag cagcataccg
     1441 gcgtaccggt ttatattcag catgatatca gcgcatggac gatggctgag gccttgtttg
     1501 gtgcctcacg cggggcgcgc gatgtgattc aggtggttat cgatcacaac gtgggggctg
     1561 gcgtcattac cgatggtcat ctgctacacg caggcagcag tagcctcgtg gaaataggcc
     1621 acacacaggt cgatccgtat gggaaacgct gttattgcgg gaatcacggt tgcctcgaaa
     1681 ccatcgccag tgtggacagt attcttgagc tggcacagct gcgtctcaat caatccatga
     1741 gctcgatgtt acatggacaa ccgttaaccg tggactcatt gtgtcaggcg gcattgcgcg
     1801 gcgatttact ggcaaaagac atcattaccg gggtaggcgc gcatgtcggt cgcattcttg
     1861 ccatcatggt gaatttattt aacccacaaa aaatactgat tggctcaccg ttaagtaaag
     1921 cggcagatat cctcttcccg gtcatctcgg acagcatccg tcagcaggcc cttcctgcgt
     1981 atagtcagca cattagcgtt gagagtactc agttttctaa ccagggcacg atggcaggcg
     2041 ctgcgctggt aaaagacgcg atgtataacg gttctttgtt gattcgtctg ttgcagggtt
     2101 aacatttttt aactgttcta ccaaaatttg cgctatctca atttgggcca ggaaagcata
     2161 acttagactt tcaaggttaa ttattttcct ggtttatatt tgtgaagcat aacggtggag
     2221 ttagtgatgc tgaagcgttt ctttattacc ggtacagaca cttctgtagg gaaaacggtg
     2281 gtttcccgcg cattgctaca agcgttagcc tcccagggaa aaacggttgc gggatataaa
     2341 cccgtagcga aggggagcaa agagacaccc gaagggctgc gtaataaaga tgccctggtg
     2401 ttgcagagtg tttcaaccat cgaactgcct tatgaagcag ttaatcctat cgcgttaagc
     2461 gaagaagaaa gtagcgtggc gcacagttgc ccaatcaatt acaccctcat ttcaaacggc
     2521 ctggcaaacc tgaccgataa agtcgatcat gtcgtggtag aagggactgg cggctggcgc
     2581 agtctgatga atgatttgcg tccgctctct gaatgggtgg tgcaggaaca actgccggtg
     2641 ttgatggttg tcggtattca ggaaggttgc attaaccatg cactgctaac agctcaggcg
     2701 attgccaacg acgggctgcc gctcattggc tgggtggcta accgaatcaa cccaggactg
     2761 gcgcattatg cggaaatcat tgatgtgctc ggtaaaaaac ttccggcacc gctcattggt
     2821 gaactgcctt atctgccgcg cgccgaacag cgtgaactgg ggcaatacat ccgcttagct
     2881 atgcttcgca gtgtgctggc ggtagataga gtcacggtgt aacgtccgcg aaattaccga
     2941 cgcaattacg caggcaatca ataaaccggg gagtagctga tactccccgg tcatttcaca
     3001 tatcatcaac gtcgacatag tcggcgcgtg cgtggtcgcc gccaacagtg tcgccatccc
     3061 ggtcaatccg agtaaaagcg taatttcttc gccatcaggt aaccataatc ccaggctacg
     3121 accatacaac atgccaatgg caagaccgat aaatagcgtc ggtgtaaaga caccaccggg
     3181 cgcgccagaa ccactactcg ccagcacggc acacagttta cagaggaaga tcccggcaat
     3241 gatcattaac agtggcggag cggttaaaaa ggattgtacg gtgctatagc cgttgcccca
     3301 cactgcaggt gtgaacaggg aaagaagacc cacgatcaac ccgcccagtg ccagttgcca
     3361 gggcggcgca agcttgagac tcacaaatcc acgatgacag gcgttcatta acgttaacaa
     3421 cagtggtccg cacagacctg ccagcacacc tgtactgata atcagcgcat agtcacgagc
     3481 ctgaaccgtc actgaaagtt gtacgctgta gagtaatgcg tcgctatgat taataagatt
     3541 gctaaccagc aacgccacga cggcggaaat aatcaccggg ccgagagagg ccaacatcat
     3601 agtgccaaac agcacttcgg ctataaataa actaccagca agcggggcgc gataggccgc
     3661 agccattccc gccgcagctc cacaggcgat ccataatttc cactcctggc gtggcgtaaa
     3721 acgttgggca aaacacgagg ctgcaagggc agctaaaaga atcatcgcac cttcgcgacc
     3781 aattgcactg ccgctggtta ctaccagcag agaggcaagc gatttaacca gacttgctgc
     3841 gtaatcaaac tgaccatcgg tttgcaacgc ttccatgtaa tcggtcggcg catgagggcg
     3901 ttgctgggta aatttctgcc agcccatcag caacaaaccc gccgccagtc cgccgagcgc
     3961 cggggttagc agccgtcgcc acggggaaag atttgtcgct gcattgacca gactgccaga
     4021 gtcattattg aggaacagcc actccagtag cagcatcgca tgacgaaacc cggcaacggc
     4081 aaaggccgca agaataccga cgattgttgc gataagcaga cggcggaaca tagtgcgcag
     4141 atccggatag atgtgtagat gatgcatgag cagaaatggg caatgaaaca cgggcgacta
     4201 ttttgcggca aaagaggcca gccgcaaaag cagtgtgtgc tttaagagat aaaaaaaacg
     4261 tgacactgta acctattaat tgccgaattg cgtgtaatcg tcaccatccg gcaataatac
     4321 ggtgatccta tcgaaacagc ggtttaaccg cgacaggaat caacagttgt gattgccatt
     4381 gcgccagcgt taagcgagcg agttcaccca gtgcacggta gaaagggtgt tctgcttttt
     4441 cgataaaaac gtcaagaaaa cgtgttgacc acggaaaaag gtgccatgcc agcaattctt
     4501 cgcattctgt ctggcgacca ttctccgcca accacgcagc catcagcagc agtgaaccaa
     4561 aattatcttc cggttcgttt tgcttcattt cgaactgaat gcctttctcg cgcatccact
     4621 gacgaagtgc caatgttgaa tcgccaaaca gcacagattc gcgatccagc cagaccgatc
     4681 cccacggcgg agacggcagt gcccacgggc cgacaaacaa acgctgccag gcctgggcgt
     4741 gagtctcttc acattgtgtc tgaaaagccg tcaccagcgg cgctaatgac gcttctggta
     4801 gaggccactg agtttcccag ccgtcattgg tgagtaccgc aaccagaggt gcggcttccg
     4861 cactctctgg agcgtaataa aacagcgcgc ccaacacgcg cgccgcaaca gaaaaattat
     4921 cttgctgtga aaaatgggtc attcctaaca tcctgaaatg tgcgggttgc cccgcaccaa
     4981 tttgttaacc tgcaatagcc attcctaccg tcatgtgcag gccataaaag agcacacgcc
     5041 cgatcatctc accgccaaga atgaggatta gccccagaac aagtccggca acgtgaggtt
     5101 cacggcgacg aatgagcgga caaagccagc atccaagacc tgcgcataac aataccacac
     5161 gccagacctg taaggaggcg taatctggta ccagtgcgct ggcttgttgt acggatgagt
     5221 gaatagacgc cagagacaaa ccttgcagca caatcaaccc ggcacaagcg atcagcgcca
     5281 gaatgctaat gatggcaaat ggtgtggtat taaatgtaac gcgggctgca cgcagaattg
     5341 tggcagcaag tattggaccg ctcaacaata ccgtcaggaa gaaagccagc gtagtgtaac
     5401 cgttatgcca ggttggcaca gtgtcgattt gatacacgca ggtcatcatc cagacgaaaa
     5461 tgatgccgag tgccatgctg acaagtaacc agagtttccc caacgcttgc ggcattttac
     5521 cgatgaccgc caccagccac cataatccgc caacggcaaa aaatatggaa ccggcagcaa
     5581 tctcgttact cagaccagaa gctccgattc tattcagcga gttaaacgcc cgcagtggcg
     5641 atcccaggtg catgacagag gcaataaacc cgatgcccat caacagccag aggaaaaaca
     5701 tgccacgaat aatgtgctga cggtctgcgt catttttggc ggcgaaccag ccaattccgc
     5761 taacaatcag cgcgcctact acgcattgac ccaatacggt aaagataacc agtggccatt
     5821 catgccatcc atttcccatt ttacacttcc tccggattag ccagataacc agtggtatcg
     5881 ccggtcgggc ggctgttggc gttaggtttg ataacgatat tgggttttgt gaaatgcgcg
     5941 cgcggcagtg gcgcgacggc agccagagtg ccgtgcttct ggcgcaattc ttcaattgga
     6001 ccgaactcaa gtgcacgcag tgggcaggat tcgacacata tgggttgttt cccctcggcg
     6061 acgcgcgaat aacaaccatc gcacttcgtc atgtgccctt tttcagcatt gtactgtggc
     6121 gcgccgtacg gacaagccat gtggcagtag cggcagccga tacaaacatc ttcatcgacc
     6181 accacaaagc catcttctcg tttgtgcatt gcgccgctgg ggcagacttt ggtacacgcc
     6241 ggatcatcgc agtggttgca cgaaattgag agatagtagg caaagacatt ctgatgccag
     6301 acgccattat cttcctgcca gtcgccgcca gcatattcat aaatacggcg gaaactgact
     6361 tccgggccaa gatctttaaa atctttgcac gccagttcgc aggttttaca gccagtacag
     6421 cggctggaat cgataaaaaa tccatattgt gtggtcatgg gctactcctt aaaccttttc
     6481 gatctggaca agattgctgt gcgacgggtt tccctttgcc agcggtgaag ggcggtgaga
     6541 ggtcagaata ccgttaactg cagtggatag gtcccccgta ggggatcgtt ccaaccgtcg
     6601 aaacctgggg tatacgctgg cagtggatga ataatttcat cttttttcaa ttcccaggta
     6661 tccgcaattg tcgccagtcg ttcagaataa atttcgattt ttcccgaagg tgttttcaac
     6721 gggtttgcct gtggatctac acggaatgcg cggaaagcga cgtagtgttc ttccgggcat
     6781 tttttcttaa agatcccggt cgttttcatc tcctcgtagt cgggcatctc agggttacgt
     6841 tccttcgttt tcgcatggag atatttgatc cattcatgct gactgcgacc ttcagtaaag
     6901 gtttgataaa cgtctggtcc taagcgtttg gcgacttcac tcagcatcca gtagatgggt
     6961 ttgcgttcaa attttgctga ggttgcgggt tgggcgagga tcacatagcc catattcccg
     7021 gcagattcat gagagataag gtcttcttgc tctgttggca tcaggtcggg taacaggata
     7081 tcgcaatact tagccgaggc agtcatgaag tggtcaatgc caacaatcat ctcgcacttg
     7141 ctgtcatcct gaagcacctc atgggtgtga ttgatgtcgc catgctgatt gatcaatgtg
     7201 ttactggcgt agcaccataa aaacttgatg gggacatcca gtttttcttt tcctcgaaca
     7261 ccatcacggg tcgcggtcat ttccgtacca tggtcgatgg catctgtcca tgtaaagacg
     7321 gaaagccgct catccgcgtt tctgacgggt tatttccgaa cataacgacc agtttcgtat
     7381 tggcgatatc atccgggctg ttgccatcat tggcaccgaa catataactc attgcggcac
     7441 tgatctgtgc ggtactgtag ctgccatagc gactgagaaa accaccgcaa gagttcatca
     7501 gacggtacgg gacgtttgag ttggtgatgt ttccgccatc tacgcctgtt ccatagagaa
     7561 catgtacagc ctcattgccg taatctttta ggatccgccg aagattatca ctgatggtat
     7621 ccagggcttc gtcccaactt atccgttcaa atttaccttc accgcgcttg ccgacgcgct
     7681 tcatgggata tttcaacctg tcaggatgat tcatccgtcg gcggatagag cgcccgcgta
     7741 aacatgcccg aacctgatga ttaccgtaaa cgtcgtcacc tgtcgtatca gactccaccc
     7801 agtacacggt gtcatctttc acatgcaaac gtaacagaca gcggctcccg cagttaacgg
     7861 tgcaggaact ccagaccgct ttctcttcta ccggtgcctg tgccgctcgg accatttggg
     7921 aaaacggcaa agtgaaagca ctgcttgcca gcgcgagact gccaagtgcg gaggttttca
     7981 tcagacttct acgactgatt tcagccgaca tgagcgcctc tgtgttatgg attttcatca
     8041 ttactcactt attgcttttc aaacaaaatg tcatgtcaaa atttatggcc gtagtgggtt
     8101 atattttttc gatctcgacc agattagtgt gctgcgggtt tcccttcgcc agtggtgaag
     8161 ggcgcagagt ggttagcgta ttcacacagc cgccgtggtc gattttatcg ccagacatat
     8221 tggcctcgtg ccaggctccc tggcccatag cactaactcc agggagaatg cgtggtgtca
     8281 ctttggctgg tagccgaact tcgccacgat ggttaaacac ccgcaccata tcgccgttgg
     8341 caatcccacg tttctgtgca tctatagggt tgatccacac ttcctgacgg caggctgcct
     8401 tcaggacatc aatgttgccg taggtcgagt gcgtacggga tttgtaatgg aaaccaaaca
     8461 gttgcagtgg gaaggtacta cgttcagggg agtcccaccc ttcaaaggtt gaggcataaa
     8521 ccggcagtgg gcttatcact tcatcttttt ccagttccca ggtacgggca atttccgcca
     8581 gcttgctgga ataaatttca atcttaccgg aaggcgtttt aagtggattt gcctcggggt
     8641 cgtcacgaaa tgctttgtag gcgacaaaat gaccattggg atctttacgc ttatagatac
     8701 ccattttttt taattcgtcg taagacggta acgccggatc tttggcaagc attttggcgt
     8761 acagatgttg taaccattgt tcttgcgtgc gaccttcagt gaacttttga tagacgtcag
     8821 gtccaagacg tttcgcgact tcactcagga tccagtaaat tggtttgcgt tcgaattttt
     8881 cgctggtgac aggctggagg aaaatgagat atcccatgtt accggcgtag tcgttaggaa
     8941 taatatcttc ctgctcaacg gtcattaggt ctggcagcag aatgtcggca tattttgccg
     9001 atgaggtcat aaagttttcg atgaccacaa tcatttcgca tttcgattcg tcctgcagaa
     9061 tttcatgcgt tttgttgatg tcagaatgct gattaaccag ggtatttccc gcgtagttcc
     9121 agatgaactt aatgggcaca tctagtttat ctttgccccg gacgccgtcg cggattgccg
     9181 tcatttgcgg gccatgatcg atagcatctg tccaactgaa gcaggagatt gacgttttga
     9241 ccggattatc cagcaccggc aggcgttcga tggtaatggt gtaggtcgat tcacgcgcac
     9301 cactatttcc gccgctgatg ccgacattgc ccgtcaaaat aggcaacata gcaatagcgc
     9361 gtgccgtcag ctcgccgttt gcctgccgtt gcggccccca gccctggcag atataagcgg
     9421 gttttgctgt gccaatttca cgcgccagtt tgatgatacg gtctaccggg atacctgtaa
     9481 tttgcgaagc ccactgcggc gttttcgctg ttttatcatc accttcacca agaatatagg
     9541 ctttatagtg accatttttg ggtgcatctg cgggtaaggt tttttcgtca tagccgacgc
     9601 agtatttatc gagaaaaggt tgatcaacga gattttcgtt aatcaatacc caggcaatac
     9661 ccgcaaccag cgcggcatcg gtgcccgggc gaataggaag ccattcatct tcacgaccag
     9721 cagccgtatc ggtatatcgc ggatcgataa caatcatttt tgcgttcgat ttctcgcgcg
     9781 ctttttcaag aagataagtg atgccaccgc cgctcatgcg ggtttcagcc gggttgttac
     9841 caaacatcac gaccagcttg ctgttttcaa tatccgtggt gctgttgcca tcattactgc
     9901 cgtaggtgta gggcatggca caggaaattt gcgcagtgct gtaggagcca tactggttta
     9961 gtgaaccgcc gtagcagttc atcaggcgtt tgaccgccga ggctgatgga gaagagcggg
    10021 tcatattgcc gccaacaatc cccgaagagt actgaatata tacagcctca ttgccatatt
    10081 gttcgacggt ttttttcagg ctactggcga tagtatccag ggcttcatcc cagctaatcc
    10141 gttcgaattt gccttcgccg cgtttgccca cgcgtttcat tgggtaattc aggcgatcgg
    10201 gatgattaat acgccgacgg atggagcgac cgcgcaaaca ggcgcgtacc tgatggttgc
    10261 catacttgtc gctgccggtg ttgtcagttt ccacccaggt cacttcatta tctttaacat
    10321 gcagacgaag tgcacagcgg ctaccacagt tgacggaaca ggcaccccag accacttttt
    10381 cgctggcctg ttgtaccgct gctgctgcac tgcgcagggt aaacggcaaa gaaaaaccgc
    10441 ctgcagccag cgccagagaa cctatcgcag tagatttaac gagtgttctg cggctgatgc
    10501 ccaccatttg ttcatttttg gacataactc act
//
LOCUS       DAFGPF010000154        10521 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFGPF010000154 DAFGPF010000000
VERSION     DAFGPF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10521
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.154"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..282
                     /locus_tag="LSX49_004582"
     CDS             <1..282
                     /locus_tag="LSX49_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001460230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7170880.1"
                     /translation="AAKKGTVKLAFSGPRVSGHNEELDTSGGTGTAIVVQAAGKNVSF
                     DGTEGDANTLKDGDNVLHYTAIVKKSSANNAQVTEGAFSAVATFNLSYQ"
     gene            345..932
                     /locus_tag="LSX49_004583"
     CDS             345..932
                     /locus_tag="LSX49_004583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7170881.1"
                     /translation="MKNFCVLFVMYFWSTLLHAVSSEPFPPPGMSLPEYWGEEHVWWD
                     GRAAFHGEVVRPACTLAMEDAWQIIDMGESPVRDLQNGFSGPERKFSLRLRNCEFNSQ
                     GGNLFSDSRIRVTFDGVRGETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLT
                     GNEEALDYTLRIVRNGKKLEAGNYFAVLGFRVDYE"
     gene            991..3501
                     /gene="papC"
                     /locus_tag="LSX49_004584"
     CDS             991..3501
                     /gene="papC"
                     /locus_tag="LSX49_004584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_151035092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P fimbrial usher protein PapC"
                     /protein_id="HBL7170882.1"
                     /translation="MKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNID
                     FTRFSEAGYVLPGQYLLDVIVNGQSISPASLQISFVEPQSSGDKAEKKLPQACLTSDM
                     VRLMGLTAESLDKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWLEYSDATW
                     LPPSRWDDGIPGLMLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQ
                     EQSRYNGEKTTNRNFTWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESD
                     DRMLPPRLRGYAPQITGIAETNARVVVSQQGRVLYDSMVPAGPFSIQDLDSSVRGRLD
                     VEVIEQNGRKKTFQVDTASVPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWG
                     LSNQWSLYGGAVLAGDYNALAAGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRL
                     SYSKRFDNADADITFAGYRFSERNYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVAD
                     WNTSFNLQYSRQTYWDIRKTDYYTVSVNRYFNVFGLQGVAVGLSASRSKYLGRDNDSA
                     YLRISVPLGTGTASYSGSMSNDRYVNMAGYTDMFNDGLDSYSLNAGLNSGGGLTSQRQ
                     INAYYSHRSPLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGGTRLLV
                     DTDGVGGVPVDGGQVVTNRWGTGVVTDISSYYRNTTSVDLKRLPDDVEATRSVVESAL
                     TEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLAWLSGV
                     TPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCTPQK"
     gene            3572..4306
                     /locus_tag="LSX49_004585"
     CDS             3572..4306
                     /locus_tag="LSX49_004585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBL7170883.1"
                     /translation="MWKLSMIRKKILMAAIPLFVISGADAAVSLDRTRAVFDGSEKSM
                     TLDISNDNKQLPYLAQAWIENENQEKIIAGPVIATPPVQRLEPGAKSMVRLSTTPDIS
                     KLPQDRESLFYFNLREIPPRSEKANVLQIALQTKIKLFYRPAAIKTRPNEVWQDQLIL
                     NKVSGGYRIENPTPYYVTVIGLGGSEKQAEEGEFETVMLSPRSEQTVKSANYNTPYLS
                     YINDYGGRPVLSFICNGSRCSVKKEK"
     gene            4343..4924
                     /locus_tag="LSX49_004586"
     CDS             4343..4924
                     /locus_tag="LSX49_004586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein papJ"
                     /protein_id="HBL7170884.1"
                     /translation="MVVNKTTAVLYLIALSLSGFIHTFLRAEERGIYDDVFTADELHH
                     YRINERGGRTGSLAVSGALLSSPCTLVSNEVPLSLRPENHSAAAGAPLMLRLAGCGDG
                     GALLPGKRGVAMTVSGSLVTGHGTGSALLPDRKLSGCDHLVIHDGDTFLLCRPDRRQE
                     DMLAAWRKRAAQEGEYSDARSNPAMLRLSIKYE"
     gene            4934..5470
                     /locus_tag="LSX49_004587"
     CDS             4934..5470
                     /locus_tag="LSX49_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001558207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7170885.1"
                     /translation="MIKSTGALLLFAALSAGQAIASDVAFRGNLLDRPCHVSGDSLNK
                     HVVFKTRASRDFWYPPGRSPTESFVIRLENCHATAVGKIVTLTFKGTEEAALPGHLKV
                     TGVNAGRLGIALLDTDGSSLLKPGTSHNKGQGEKVTGNSLELPFGAYVVATPEALRTK
                     SVVPGDYEATATFELTYR"
     gene            5497..6024
                     /locus_tag="LSX49_004588"
     CDS             5497..6024
                     /locus_tag="LSX49_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7170886.1"
                     /translation="MKKIRGLCLPVILGAVLMSQHAHAADNLTFKGKLIIPACTVQNA
                     EVNWGDIEIQKLVQSGGNQKDFTVQMTCPYHLGTMKVTISTSAATYNKGIIVKGTSSR
                     TDDGLLIYLYNRHQNGSIGDAITLGTPFTPEHVSGQVPARNISLYAKLGYKGDIQNLR
                     AGTFSATATLVASYS"
     gene            6099..6599
                     /gene="papF"
                     /locus_tag="LSX49_004589"
     CDS             6099..6599
                     /gene="papF"
                     /locus_tag="LSX49_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042092232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P fimbrial tip protein PapF"
                     /protein_id="HBL7170887.1"
                     /translation="MARLSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVV
                     DFGNINPEHVDNSRGEITKTISISCTYKSGSPWIKVTGNAMAGQTNVLATNIANFGIA
                     LYQGKGMSTPLTLGNGSGNGYRVTAGLDTARSTFTFTSVPFRNGSRTLNGGDFRTTAS
                     MSMIYN"
     gene            6643..7653
                     /gene="papG-II"
                     /locus_tag="LSX49_004590"
     CDS             6643..7653
                     /gene="papG-II"
                     /locus_tag="LSX49_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_151505562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P fimbria tip G-adhesin PapG-II"
                     /protein_id="HBL7170888.1"
                     /translation="MKKWFPALLFSLCVSGESSAWNNIVFYSLGDVNSYQGGNVVITQ
                     RPQFITSWRPGIATVTWNQCNGPEFADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEV
                     HNKGSWSEENTGDNDSYFFLKGYKWDERAFDTANLCQKPGETIRLTEKFDDIIFKVAL
                     PADLPLGDYSVTIPYTSGIQRHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCR
                     PSAQSLEIKHGDLSINSANNHYAAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVG
                     LGHGWDSIVSVNGVDTGETTMRWYKAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMI
                     LP"
     gene            7916..8467
                     /gene="papX"
                     /locus_tag="LSX49_004591"
     CDS             7916..8467
                     /gene="papX"
                     /locus_tag="LSX49_004591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PapX"
                     /protein_id="HBL7170889.1"
                     /translation="MRACTQTVCFSNMENNEMNNTDTLEKIIRHQKNKDPAYPFREHL
                     LMQLCIRTNKRMQDNISEFLGVYGINHSVYMVLTTLFAAESHCLSPSEISQKLQFTRT
                     NITRITDFLEKAGYVKRMDSREDRRAKKISLTSEGMFFIQRLTLAQSMYLKEIWGYLT
                     HDEQELFEVINKKLLAHLDDVSS"
     gene            complement(8952..9251)
                     /locus_tag="LSX49_004592"
     CDS             complement(8952..9251)
                     /locus_tag="LSX49_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170890.1"
                     /translation="MALLWNQAAGSINLEFISYWNSGVLAAPDNHLTHEERSALQKLW
                     GGLETGDVTIIGRSDEVHDFTSALINCFLSEEEIVWWQSGGIFPDPWPANISRLN"
     gene            10027..10395
                     /locus_tag="LSX49_004593"
     CDS             10027..10395
                     /locus_tag="LSX49_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170891.1"
                     /translation="MSAQEKTVQIDSFDAKFLDINTLSKLIYERKSFVIENVSDVSET
                     VKRVEHEIEKTKLSCRVYTEYRSTALAGSLWSPTVILGVASAVAIGVHNLSTWNPDYE
                     IGKNYIKRRLSVKYKKAEVL"
BASE COUNT         2809 a         2196 c         2727 g         2789 t
ORIGIN      
        1 gcagcaaaaa aagggactgt gaagctggct tttagtggtc caagggtttc tggtcataat
       61 gaggagttag ataccagcgg ggggacaggt actgcgattg tagttcaggc tgcaggtaaa
      121 aacgtttctt tcgatggcac agaaggtgat gctaataccc tgaaagatgg tgataatgtg
      181 ctgcattata ctgcgattgt taagaagtcg tcagccaata atgcccaagt tactgagggt
      241 gctttttctg cagtcgcaac ctttaattta agttaccagt aattcatctg atttttacag
      301 ggtgaggcaa gacccaccct gtgtctgaca acgacattta aggtatgaag aatttttgtg
      361 ttctgtttgt gatgtatttc tggagtacat tacttcatgc tgtatcttca gagccatttc
      421 ctccgcccgg catgtccctt cctgaatact ggggagaaga acacgtatgg tgggacggca
      481 gggctgcttt tcatggtgag gttgtcagac ctgcctgtac tctggcgatg gaagacgcct
      541 ggcagattat tgatatgggg gaaagcccgg ttcgggattt acagaatggt ttttccggac
      601 ctgaaagaaa attcagcctc cggctcagga actgtgaatt taacagtcag ggtgggaacc
      661 ttttctctga ttcccggata agggtgactt tcgatggcgt ccggggtgaa acgccagata
      721 agtttaattt atccggtcag gcaaaaggca ttaatctgca gatagctgat gccaggggga
      781 atattgcccg ggcagggaaa gtaatgcctg caataccatt gacgggtaat gaagaagcgc
      841 tggattacac cctcagaatt gtgcgaaacg gaaaaaaact tgaagccgga aattattttg
      901 ccgtgctggg attccgggtc gattatgagt gagtcactcc ggtgagatgt ccggttattt
      961 atcttttttg tgaatctggt gatgcgtgga atgaaagaca gaataccttt tgcagtcaac
     1021 aatattacct gtgtgatatt gttgtctctg ttttgtaacg cagccagtgc cgttgagttt
     1081 aatacagatg tacttgacgc ggcggacaag aaaaatattg acttcacccg tttttcagaa
     1141 gccggttatg ttctgccggg gcaatatctt ctggatgtga ttgttaacgg gcaaagtatt
     1201 tctcccgcat cgttacagat ttcatttgtt gaacctcagt cgtcaggaga taaggcagaa
     1261 aaaaaattgc cacaggcctg tctgacatca gatatggtca gactgatggg gttaacagca
     1321 gaatctctgg ataaagttgt ttactggcat gatggtcagt gtgcggattt tcatgggttg
     1381 ccgggagtgg atattcgtcc tgataccgga gcgggcgtat tacgcatcaa tatgccgcag
     1441 gcctggcttg agtattctga tgccacctgg ctgcctccct cacgctggga cgacggcatt
     1501 cccggactga tgctggatta taacctcaac gggacggttt cccgtaatta tcagggagga
     1561 gactctcatc agttcagtta taacgggact gtggggggga atctggggcc ctggcgcctg
     1621 cgggctgact atcagggaag ccaggagcag agccgctaca acggggaaaa aacgacaaac
     1681 agaaatttca catggagtcg cttttatctg ttccgtgcca ttccacgatg gcgggcaaac
     1741 ctgacgctgg gcgagaataa tatcaactca gatatattcc ggtcatggag ttatacggga
     1801 gccagcctgg aaagcgatga ccggatgctg ccacccagac tgcgaggcta tgcaccgcag
     1861 attaccggga ttgcggagac taatgcccgt gttgtggtgt cgcagcaggg acgggtgctg
     1921 tacgactcta tggtccccgc agggccattc agtattcagg acctggacag ttcagttcgc
     1981 ggacgtcttg atgttgaggt tattgaacag aacggacgga agaaaacctt tcaggtcgat
     2041 acggcctcgg ttccttatct gacgcgtccg ggacaggtcc ggtataaact tgtctccggt
     2101 cgctcccgcg gatacgggca tgagaccgaa gggcctgtat ttgcgaccgg agaggcgtcc
     2161 tgggggctca gtaaccagtg gtcgctgtat ggcggggctg tgcttgccgg tgattataat
     2221 gcactggcag ccggtgccgg ctgggacctg ggtgtgccgg ggaccctttc cgctgatatc
     2281 acgcagtcag tagcccgtat tgagggagag agaacgtttc agggaaaatc ctggcgtctt
     2341 agctactcca aacggtttga taatgcggat gccgacatta cgttcgccgg gtatcgtttc
     2401 tcagagcgaa actatatgac catggagcag tacctgaacg cccgctaccg taatgattac
     2461 agcagtcggg aaaaagagat gtataccgtt acgctgaata aaaacgtggc ggactggaac
     2521 acctctttta acctgcagta cagccgtcag acatactggg acatacggaa aacggactat
     2581 tatacggtga gcgtcaaccg ctactttaat gttttcggac tgcagggtgt ggcggttgga
     2641 ttgtcagcct caaggtctaa atatctgggg cgtgataacg attctgctta cctgcgtata
     2701 tccgtgccgc tggggacggg gacagcgagc tacagtggca gtatgagtaa tgaccgttat
     2761 gtgaatatgg ccggctacac tgacatgttc aatgacggtc tggacagcta cagcctgaac
     2821 gccggcctta acagtggcgg tggactgaca tcgcaacgtc agattaatgc ctattacagt
     2881 catcgtagtc cgctggcaaa tttgtccgcg aatattgcat ccctgcagaa aggatatacg
     2941 tctttcggcg tcagtgcttc cggtggggca acaattaccg gaaaaggtgc ggcgttacat
     3001 gcagggggaa tgtccggtgg aacacgtctt cttgttgaca cggatggtgt gggaggtgta
     3061 ccggttgatg gcgggcaggt ggtgacaaat cgctggggaa cgggcgtggt gactgacatc
     3121 agcagttatt accggaatac aacctctgtt gacctgaagc gcttaccgga tgatgtggaa
     3181 gcaacccgtt ctgttgtgga atcggcgctg acagaaggtg ccattggtta ccggaaattc
     3241 agcgtgctta aagggaaacg tctgtttgca atactgcgtc ttgctgatgg ctctcagccc
     3301 ccgtttggtg ccagtgtaac cagtgaaaaa ggccgggagc tgggcatggt ggccgacgaa
     3361 ggccttgcct ggctgagtgg cgtgacgccg ggggaaaccc tgtcggtaaa ctgggatgga
     3421 aaaatacagt gtcaggtaaa tgtaccggag acagcaatat ctgaccagca gttattgctt
     3481 ccctgtacgc ctcagaaata aatgaaagtc cggaatatta acggctgatg aatgcggtta
     3541 tgccattttc cggaccaggt gaaattacag aatgtggaaa ttaagtatga ttcgaaaaaa
     3601 gattctgatg gctgccatcc ccctgtttgt tatatccggg gcagacgctg ctgtttcgct
     3661 ggacagaacc cgcgcggtgt ttgacgggag tgagaagtca atgacgcttg atatctccaa
     3721 tgataacaaa caactgccct atcttgctca ggcatggata gaaaatgaaa atcaggaaaa
     3781 aattattgca gggccggtta ttgccacccc tccggttcag cgccttgagc cgggtgcgaa
     3841 aagcatggtc aggctgagta ccacaccgga tatcagtaaa cttcctcagg acagggaatc
     3901 actgttttat tttaatctcc gggaaatacc gccgaggagt gaaaaggcca atgtactgca
     3961 gatagcctta cagaccaaaa taaagctttt ttatcgcccg gcagcaatta aaaccagacc
     4021 aaatgaagta tggcaggacc agttaattct gaacaaagtc agcggtgggt atcgtattga
     4081 aaacccgacc ccctattatg tcactgttat tggtctggga ggaagtgaaa agcaggcaga
     4141 ggaaggtgag tttgaaaccg tgatgctgtc tccccgttca gagcagacag taaaatcggc
     4201 aaattataat accccttatc tgtcttatat taacgactat ggtggtcgcc cggtactgtc
     4261 gtttatctgt aatggcagcc gttgctctgt gaaaaaagag aaataatgta ccgcaataac
     4321 ggttaaatgc gggtgggata ttatggttgt gaataaaaca acagcagtac tgtatcttat
     4381 tgcactgtcg ctgagtggtt tcatccatac tttcctgcgg gctgaagagc ggggtatata
     4441 cgatgacgtc tttactgcag atgagttgca tcattaccgg ataaatgaac gggggggacg
     4501 caccggaagc ctggcagtca gtggtgcact gctgtcctca ccctgcacgc tggtgagtaa
     4561 tgaggtgccg ttaagcctcc ggccggagaa tcactctgcg gcagccggag ctcctctgat
     4621 gctgaggctg gcaggatgtg gggacggtgg tgcacttctg cccggaaaac ggggcgttgc
     4681 gatgacagtc tccggctcac tggtaaccgg tcacggaacc ggaagtgctt tacttcctga
     4741 ccgtaagcta tccggctgtg accatcttgt tatacatgat ggtgatacct ttttactgtg
     4801 ccggcctgac cggcggcagg aggatatgct ggcagcctgg aggaaaaggg cggcacagga
     4861 gggtgagtat tctgatgcca ggagcaatcc ggccatgctg cgtctgagca taaaatatga
     4921 gtaagggaat gtgatgataa aaagcacagg cgctctttta ctgtttgccg cactgtctgc
     4981 cggacaggca atagcctcag atgtggcatt caggggtaat ctgcttgaca gaccctgcca
     5041 tgtgtccggt gacagtctga ataaacatgt cgtcttcaaa acccgggcgt ccagggattt
     5101 ctggtatccg cccggacgtt cgccgacaga gtcgtttgtc atcaggctgg aaaactgcca
     5161 tgcaacagca gttggcaaaa ttgtgaccct gacctttaag ggaacggaag aggcggccct
     5221 cccgggccat ctgaaggtaa ccggagtgaa tgccggccgg ttaggcattg cactgctgga
     5281 caccgatggc agcagtctgc tgaaacccgg cacctcccat aacaaaggcc agggagaaaa
     5341 ggttaccgga aacagtcttg agcttccttt cggcgcgtat gttgtggcaa cgccggaagc
     5401 cctgcggacg aagagtgtgg tacccggtga ttatgaagca acagccacgt ttgaattgac
     5461 atatcgttag aaaaaatttt gtacaggata tttcagatga aaaagataag aggtttgtgt
     5521 cttccggtaa tactgggggc agtgttaatg tctcagcatg cacatgcagc tgataatctg
     5581 acctttaaag gaaaactgat tattcctgcc tgtactgtac aaaatgctga agttaactgg
     5641 ggtgatattg aaattcagaa gctggtacag agtggcggaa atcagaaaga ctttactgtc
     5701 cagatgacat gtccttatca tttgggaaca atgaaggtta cgatatctac atcggcagcg
     5761 acttataaca agggaattat agttaagggt acctcatccc ggaccgatga tggattgctt
     5821 atttatctgt acaatcgtca tcaaaatggc agtatcggtg atgctataac tctggggaca
     5881 ccattcacac cagagcatgt ctcaggtcag gttccggcca gaaacatttc tctctatgca
     5941 aaacttggat ataaaggaga tatacagaat ttgcgggcgg gaacattttc tgcaacggca
     6001 acgctggttg catcatattc gtaatgctat cagttaaaat acgccgattt tatatctcat
     6061 aaaataaaat attttctgta ccgctctccg gagggggaat ggctcgttta tcattattta
     6121 tatcgttgct tctgacatcg gtcgctgtac tggctgatgt gcagattaac atcaggggaa
     6181 atgtttatat ccccccatgc accattaata acgggcagaa tattgttgtc gattttggga
     6241 atattaatcc tgagcacgtg gacaactcac gtggtgaaat cacaaaaacc ataagcatat
     6301 cctgtacgta taagagtggc tcaccctgga taaaggtcac aggtaatgca atggctgggc
     6361 agactaatgt actggcaaca aatatagcca attttggtat agcgttgtat cagggaaaag
     6421 gaatgtcaac acctcttaca ttaggtaatg gttcaggaaa tggttacaga gtgacagcag
     6481 gtctggacac agcacgttca acgttcacct ttacttcagt gccctttcgt aatggcagca
     6541 ggacactgaa tggcggggat ttccggacca cggccagtat gagcatgatt tataactgag
     6601 tcatacctaa atgaataact gtaattacgg aagtgatttc tgatgaaaaa atggttccca
     6661 gctttgttat tttccttgtg tgtgtctggt gagtcctctg catggaataa tattgtcttt
     6721 tactcccttg gagacgttaa ctcttatcag ggagggaatg tggtgattac tcaaaggcca
     6781 caatttataa cttcgtggcg cccgggcatt gctacggtaa cctggaatca gtgtaatggt
     6841 cctgagttcg ctgatggctc ctgggcttac tacagggagt atattgcgtg ggtagtattc
     6901 cccaaaaagg ttatgaccaa aaatggatat cccttattta ttgaggttca taataaaggt
     6961 agctggagtg aggagaatac tggtgacaat gacagctatt tttttctcaa ggggtataag
     7021 tgggatgagc gggcctttga tacagctaat ttgtgtcaga aaccaggaga aacaatccgt
     7081 ctgactgaga aatttgacga tattattttt aaagtcgccc tacctgcaga tcttccttta
     7141 ggggattatt ctgttacaat tccatacact tccggcatac agcgtcattt cgcgagttac
     7201 ttgggggccc gttttaaaat cccatacaat gtggccaaaa ccctcccaag agagaatgaa
     7261 atgttattct tatttaagaa tatcggcgga tgccgtcctt ctgcacagtc tctggaaata
     7321 aagcatggtg atctgtctat taatagcgct aataatcatt atgcggctca gactctttct
     7381 gtgtcttgcg atgtgcctgc aaatattcgt tttatgctgt taagaaatac aactccgaca
     7441 tacagccatg gtaagaaatt ttcggttggt ctggggcatg gctgggactc cattgtttcg
     7501 gttaacgggg tggacacagg agagacaacg atgagatggt acaaagcagg tacacaaaac
     7561 ctgaccatcg gcagtcgcct ctatggtgaa tcttcaaaga tacaaccagg agtactatct
     7621 ggttcagcaa cgctgctcat gatattgcca taaatggttt atccggagcc ggatagagtg
     7681 ttgtggatat ctgggatgcc ccgggaagtc acctttcaga cgggcggagg gctggtgaat
     7741 gatccgcgat tactgagcag tatggataat cctttttcac agacttgtca gcagccagca
     7801 tttatgttct tttatctgag ggaatttatc tgtctgctgt gtaggaatat ctcagttata
     7861 cagaaatcag gcaggaataa attgtagtgg aaagtcgatg tttaccggat gactgatgcg
     7921 cgcttgtaca cagacagtgt gtttcagtaa tatggagaat aatgaaatga ataacacaga
     7981 cacattagaa aaaataatca gacaccaaaa aaacaaagac cccgcatatc cctttcggga
     8041 gcatttgttg atgcaactct gtattcgcac aaataaaaga atgcaggata atatatctga
     8101 atttctgggg gtgtatggaa taaatcactc agtatatatg gttctcacca cattattcgc
     8161 agcggagagt cattgtctgt caccttcaga gataagccag aaacttcagt ttaccagaac
     8221 taatattacc cgcattacag attttttaga aaaagccgga tatgtaaaaa ggatggatag
     8281 cagggaggat cgccgtgcta aaaaaatcag tctgacatct gaaggtatgt tttttattca
     8341 gaggctcact cttgcacaaa gcatgtatct gaaagaaatc tggggttatc tgacccatga
     8401 tgaacaggaa ctgtttgaag tcattaataa aaaattactg gcgcatcttg atgatgtcag
     8461 ctcataaagc gtgaaatgcc tgagtatgcc ggatagcttc aggcaaaaga ataatgattc
     8521 ttgcagatgt gtttttccgg atacaaaaac aaatgataaa aattgcagcg ccaggcacct
     8581 ttcaaagcag ggagacctgt accgcgtcga aaatttcagc cagttaatat cattgtctga
     8641 accaggcact ttgcccgggc aggagaagga gttgtggcgg tctcagcccg gaacaatttg
     8701 aaaaccataa tctcgcttag ggccgtgtcc acattacgtg ggtaggatca ctcctggatt
     8761 ttctcttttt ggacattgac gtctccattg gtttaaacac ggcaatggag actgcggtga
     8821 aaagagttaa ttcccggagt gactggctgg atgccaatca atgatcggaa gcatgccaaa
     8881 ctgtgaacgg agatggatgc cgccaaatca tgatcgattc agatgccata tttgcaatat
     8941 cgcgttaatc gtcagttcag ccgggatata ttagcgggcc agggatccgg gaaaatgcca
     9001 cctgattgcc accagacaat ttcttcttca gaaagaaaac agttaattaa ggcggaggta
     9061 aaatcatgga cttcatcaga acgtcctata atcgttacat ctcctgtctc caaaccgccc
     9121 cagagtttct gcaaagcaga gcgctcttcg tgggtcaggt gattatcagg ggctgccaat
     9181 acaccggaat tccagtagct gataaactcc agattgatgc ttcctgcggc ctggttccag
     9241 agcagagcca tgtcaggtct tcctggtagc cagaaaaagc ctttattacg ataattacgt
     9301 agcgttcagt gatgatctgc taataatatt ctgtcgatcc gctaagtgtc agtgtatgcg
     9361 gtaagcccgc ccttgagtca ctatttggca actgctacat ctaaggtgac gttattcgct
     9421 ggcgccgata ttttctcgat gggagataac cctgcacact atgcagtgta atactcgagc
     9481 tactgcaagg ttacgcaatt cagtctttac tgccgttctt acattcgatt tgggtatgaa
     9541 ggctttcatc gttttaacac ctttctgcaa ttccattgtt ctgagagctt tccaccgctg
     9601 ttgtacaagg tacatggcac agttgtgtca ttaacttctg tatttcgtca gtgagaaccc
     9661 ggtgattacg tagttcatct tttgtccagt ggattggttg ccgtataaag gatcttatca
     9721 acaaagcaca gttcctctat gtcagcgacg acgtagtgct atggctcttt cccaaacgcc
     9781 catttctgac tgttcctgca acgccggtta gctgtcacta tttttatgga ttcgataaaa
     9841 aatcttcatc atgtatgatc gattttgtcg atcgattcga tcgaattttc tccttttacc
     9901 ctgccttttg catggtttta aaataggcaa aattacttgt cattcgtgga aagtgatggc
     9961 ggagataact gagcttaaaa cgtttctctt gtctccgtca cttgccatac cagccaggaa
    10021 aagaagatgt cagcacaaga aaaaacagta cagattgatt cttttgatgc gaaattttta
    10081 gatataaata cattaagcaa gcttatttat gaacgtaaga gttttgtgat cgaaaatgtt
    10141 tccgatgtta gtgaaacggt aaaaagagtg gagcatgaaa tagagaaaac gaaattaagt
    10201 tgtcgtgtat atactgagta caggagtaca gctttagctg gttctttatg gtcaccaacc
    10261 gtaattctgg gagtggcgag tgcagtagca ataggtgttc ataatttatc tacatggaac
    10321 cccgattatg aaatcggtaa gaactatatt aaacggagat tatcggtaaa atataaaaag
    10381 gcagaagtat tgtgatcggt tactccagtg cccctgcctg tttgtattct ggggaggttg
    10441 tattcacata atttcagaca ggcgttcacg tcctcactga gaagatatat ttattttgtg
    10501 tagagtaaaa gtctggcttc c
//
LOCUS       DAFGPF010000155        10514 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFGPF010000155 DAFGPF010000000
VERSION     DAFGPF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10514
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.155"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            159..2300
                     /locus_tag="LSX49_004594"
     CDS             159..2300
                     /locus_tag="LSX49_004594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HBL7170892.1"
                     /translation="MAMFTPSFSGLKGRALFSLLFAAPMIHATDSVTTKDGETITVTA
                     DANTATEATDGYQPLSTSTATLTDMPMLDIPQVVNTVSDQVLENQNATTLDEALYNVS
                     NVVQTNTLGGTQDAFVRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTL
                     YGILDPGGLINVVTKRPEKTFHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEV
                     QDEDYWRNFGKERSTFIAPSLTWFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVN
                     VDRKIRFDEPFNITDGQSDLAQLNAEYHLNSQWTARFDYSYSQDKYSDNQARVTAYDA
                     TTGTLTRRVDATQGSTQRMHATRADLQGNVDIAGFYNEILGGVSYEYYDLLRTDMIRC
                     KKAKDFNIYNPVYGNTSKCTTVSASDSDQTIKQESYSAYAQDALYLTDNWIAVAGIRY
                     QYYTQYAGKGRPFNVNTDSRDEQWTPKLGLVYKLTPSVSLFANYSQTFMPQSSIASYI
                     GDLPPESSNAYEVGAKFELFDGITADIALFDIHKRNVLYTESIGDETIAKTAGRVRSR
                     GVEVDLAGALTENINIIASYGYTDAKVLEDPDYAGKPLPNVPRHTGSLFLTYDIHNMP
                     GNNTLTFGGGGHGVSRRSATNGADYYLPGYFVADAFAAYKMKLQYPVTLQLNVKNLFD
                     KTYYTSSIATNNLGNQIGDPREVQFTVKMEF"
     gene            complement(2364..4256)
                     /gene="parE"
                     /locus_tag="LSX49_004595"
     CDS             complement(2364..4256)
                     /gene="parE"
                     /locus_tag="LSX49_004595"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBL7170893.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQIYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRLDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(4285..4866)
                     /gene="yqiA"
                     /locus_tag="LSX49_004596"
     CDS             complement(4285..4866)
                     /gene="yqiA"
                     /locus_tag="LSX49_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HBL7170894.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            complement(4866..5693)
                     /gene="cpdA"
                     /locus_tag="LSX49_004597"
     CDS             complement(4866..5693)
                     /gene="cpdA"
                     /locus_tag="LSX49_004597"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HBL7170895.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADARFQPDTASEGY"
     gene            complement(5718..6140)
                     /locus_tag="LSX49_004598"
     CDS             complement(5718..6140)
                     /locus_tag="LSX49_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HBL7170896.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            complement(6141..6770)
                     /gene="nudF"
                     /locus_tag="LSX49_004599"
     CDS             complement(6141..6770)
                     /gene="nudF"
                     /locus_tag="LSX49_004599"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HBL7170897.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            6975..8456
                     /gene="tolC"
                     /locus_tag="LSX49_004600"
     CDS             6975..8456
                     /gene="tolC"
                     /locus_tag="LSX49_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HBL7170898.1"
                     /translation="MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNTLLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            8604..9275
                     /locus_tag="LSX49_004601"
     CDS             8604..9275
                     /locus_tag="LSX49_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HBL7170899.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            9281..10441
                     /locus_tag="LSX49_004602"
     CDS             9281..10441
                     /locus_tag="LSX49_004602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HBL7170900.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLSQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
BASE COUNT         2650 a         2789 c         2593 g         2482 t
ORIGIN      
        1 attttttgtt atttctcatt tactactaca ttactgcgtg attgaatgat tctcaattac
       61 atatccgatg gcgaaataac aaacggatag tgcttagtga gcaataagaa acaattttca
      121 ctcgcgacaa tccgcgagtt tttgggataa cagactaaat ggctatgttc acaccttcat
      181 tctcaggact caaaggtcgg gcgctctttt cactgctttt tgcggcaccg atgattcatg
      241 caacagactc tgtaacgacc aaagatggcg aaacaatcac tgttacagca gatgcaaata
      301 ccgcaactga ggcaaccgat ggttatcaac ctctgagcac ctctacggcg acattaaccg
      361 atatgccgat gctggatatc ccgcaggtgg tcaatacggt tagcgatcag gttctggaaa
      421 accagaatgc gacaacgctg gatgaggcgc tttataacgt cagtaacgtg gtacagacca
      481 atacattagg cggaactcag gacgcctttg tacgccgtgg gtttggcgca aaccgggatg
      541 gctccatcat gaccaacggt ctgcgaaccg tacttcctcg cagtttcaac gccgccacag
      601 aacgtgtgga agtgctaaaa ggcccggcct ccacgctgta tggcattctc gatcctggcg
      661 gactgattaa cgtcgtgacc aagcgcccgg aaaaaacatt ccatggttcg gtttcagcca
      721 cctcctccag ttttggtggc ggcactgggc aacttgatat cacaggtccc attgaaggca
      781 ctcagctggc gtatcgcctt accggggaag tgcaggatga agattactgg cgaaacttcg
      841 gtaaagagcg cagtacattt attgccccgt cactcacatg gtttggtgat aatgcaacag
      901 taaccatgct ctattcccat cgggactata aaactccgtt cgatcgtgga acgattttcg
      961 accttacgac gaaacagccc gtaaacgttg atcgaaaaat acgttttgac gaaccgttta
     1021 atattacaga tggtcagtcc gatctggcgc aactcaacgc agaatatcat ctcaatagcc
     1081 agtggacagc acgctttgat tacagctaca gccaggataa atacagcgat aatcaggcgc
     1141 gtgttaccgc atatgatgca acgacaggaa cactgacacg gcgtgttgat gcaactcagg
     1201 gctctaccca gcgtatgcat gctactcgtg cggatctgca agggaatgtt gatattgccg
     1261 gattctataa tgagattctg ggtggggtgt catatgaata ttatgatctt ctgcgtacag
     1321 atatgattcg ctgtaaaaaa gctaaagatt tcaatattta caaccctgtt tatggtaata
     1381 ccagcaaatg tacaacggtt tcggcgtcgg acagtgatca gacgatcaaa caggagagct
     1441 actcagcgta tgcacaggac gcactctatc tgaccgataa ctggattgcc gtcgccggga
     1501 tccgctatca gtattacacg cagtatgcgg gtaaaggccg tccttttaat gtcaatactg
     1561 acagccgcga tgaacaatgg actcccaaac tggggttggt ctacaaactg acgccatcgg
     1621 tatccttatt tgccaattat tcgcaaacat ttatgccgca gtcgtcaatt gccagctaca
     1681 ttggcgatct tccaccggaa tcatctaatg cttacgaagt cggggcaaaa ttcgagctat
     1741 tcgatggtat caccgcagat attgcgctgt ttgatatcca taaacgtaat gtgttgtata
     1801 ccgaaagtat tggtgatgaa accatcgcca aaacggcagg ccgtgttcgt tcaagagggg
     1861 tagaagtcga ccttgcggga gcattaactg aaaacattaa tatcattgcc agctacggct
     1921 ataccgatgc taaggttctg gaggatcctg attatgcagg gaaaccattg ccgaatgttc
     1981 ctcgtcatac cggttcgcta ttcctgacct atgatattca taacatgcca ggcaataata
     2041 cgctgacatt tggcggtggt ggacatggtg taagccgtcg ttcggcaacc aatggggctg
     2101 actattatct gccaggctat tttgttgccg atgccttcgc cgcatacaaa atgaaattgc
     2161 agtatccggt cacactgcaa ttaaacgtca aaaacctgtt tgataaaacg tattacacct
     2221 cttccatcgc cacaaataat ctggggaatc agattggcga tccgcgtgaa gtgcaattca
     2281 cggtgaaaat ggaattttga tcaaaaaagc ccggtataca cttgtatacc gggctatgtt
     2341 ttattcttct ggcgggagga ttatcagacc tcaatctctg ccatgtcgcc tttttcttgc
     2401 aaccagttgc ggcgatcttc cgagcgtttc ttcgccagca gcatatccat catcgcgtca
     2461 gtacgctgat cgtcttcatc atcgatagtc aactgcacca gacggcgagt gttcggatca
     2521 agcgtggttt cgcgcaattg catcgggttc atttccccga gacctttaaa acgctggacg
     2581 tttggcttgc ctttcttgcg ttttaattgc tcaagtacgc cctctttctc ttcttccgtc
     2641 agcgcgtaat aaacctcttt cccgaggtca agacggtaga gcggtggcag tgcaacgtaa
     2701 acgtgaccgt gtttcaccaa tgcgcggaag tgttttacaa acaaagcgca gagcagcgtg
     2761 gcaatgtgca gaccatcgga gtcagcatcc gccaggatac agatcttgcc gtaacgaagc
     2821 tggctcaaat cgtcgctgtc aggatcgata ccgatagcta ccgaaatatc gtgcacttcc
     2881 tgcgaagcca gcacttcgtc ggaagagact tcccaggtgt taaggatctt acctttcagt
     2941 ggcatgatcg cctgatattc gcgatcgcgc gcctgcttgg cagatccgcc tgcggagtca
     3001 ccttccacaa ggaatagttc ggtacggtta agatcctgcg cggtacagtc agccaattta
     3061 ccaggcagcg ccgggccgct ggttagcttt ttacgcacca cttttttagc cgcacgcata
     3121 cgacgctggg cgctggaaat cgccatctct gccaacagct ccgccgcctg aacgttttgg
     3181 ttcagccaca ggatgaaggc atctttcacc acgcccgaaa cgaatgccgc acactgacgc
     3241 gaagagagac gttctttggt ctgcccggca aactgcggat cctgcatttt tactgacagc
     3301 acataggcgc agcgatccca gatatcttcc gccgacagct ttacaccacg cggcagaatg
     3361 ttgcggtatt cacagaactc acgcatcgcg tccagcaggc cctgacgcag gccattaaca
     3421 tgggtaccgc cctgcatcgt tgggatcagg ttgacgtagc tttcggtcag cagttcaccg
     3481 ccttccggca gccacagtag cgcccagtcc accgcttcag tatcgccagc gaaattaccg
     3541 ataaacggtt tttctggcag cgtcggtaaa ccgtttaccg cttccgccag gtaatcattc
     3601 agaccgtcct gatagcacca gcgctgttcg gtgttgttga tctcatcttt aaaagtgatc
     3661 tcaacgcccg ggcacagtac cgctttggct ttcagcacat gcgtcaggcg tgaaacagaa
     3721 aaacgcgggc tgtcaaagaa ggtttcatcc ggccagaagt gcacgctggt accggtattg
     3781 cgtttaccgc aagtgccgac aacctgtaaa tcttgcacct tttcgccatt ttcaaaggcg
     3841 atgttataga tctgaccatc gcggcgtacg ttaacttcta cgcgcttcga cagggcgtta
     3901 actaccgaaa tccccacgcc atgcaggccg ccagagaact ggtaattttt gttagagaat
     3961 ttaccgcccg cgtgcagacg gcaaagaatc agttcaaccg ccggtacccc ctcttccggg
     4021 tgaatatcta ccggcatccc gcgcccatcg tcaatcactt ctaacgactg gtcggcatgt
     4081 aagattacat ccacgcgttt tgcgtggccc gccagtgctt catcgacact gttatcaata
     4141 acttcttgcc ccaaatggtt agggcgagtg gtatcggtat acatccccgg acggcggcga
     4201 accggctcaa gcccggtgag tacctcaatg gcatcagcgt tataagtttg cgtcatggtt
     4261 taagttagca attcgagttg atcgtcagag atggtgcaga ccaagaaaat cgacgatcgg
     4321 gttgaaataa tcttcgaagc ccgtgaatgc gtggttgccg ccttctatga cagtctggcg
     4381 gcaggaagcg tagtacgcca ccgcctggcg gtaatccagc acttcatctc ccgtctgttg
     4441 cagcagccag atcaaatccg gcgcttccag cgggtcaatc tgcatgactt tgagatcgta
     4501 aatatggcgt gactctagca catattgctg cccggtgtag gggttctcgt tctgaccgag
     4561 atagtccgtc agcagttcaa acgggcgcac cgccgggttg accaccactg cgggcagcat
     4621 aaaacattgc gacaaccagg tggcgtaata tccccccagt gacgaaccga caatacccag
     4681 cgaatcgccg ccatgttcca ggacaatgga ttccagcagt tctgccgcgt cggaaggata
     4741 cggcggcagc tgcggaatga tcatctcaac gtcagggtga tgttccgcca gccagttttt
     4801 taacaagctc gcttttgcag agcgcggcga gctgttgaaa ccgtgtaaat aaagaagcgt
     4861 agacatcagt agccttctga agcggtatca ggttggaagc gtgcgtccgc caggcgatgc
     4921 acctcggtgg tcagcgtgcc atcagcatgt aactcaagag tacgccagcc gggcgcgatg
     4981 gtatccagcg taaagttgga acagtgcggc ttaaactgca cacaggtcga cggcgttgcc
     5041 agcaggcggc gaccgttcca gtcgagatcc agctcctgat gaatatgacc gcacagcaag
     5101 tatttgacgt gcggaaactt cgccagcacg gtatccagtt cgcccgcgtt acgcaggctg
     5161 tgttgatcaa gccaactaca acccgcaggt agcggatgat gatgcagcag cagcaacgta
     5221 tggcgttctg gcgcatcggc cagtttacgt tccagccact caagctgaaa ctcgctcagc
     5281 tcaccgtgcg gcacgccaaa cacctggcta tccagcaaca ggatttgcca ttgctcacca
     5341 ataaacaccc gcttcgccgg ggagataccc gcatcctgta acgcactgta catcgcgggc
     5401 tggaaatcgt ggttgcccgg cagccagacg cagggcgcac gaaaacttgc gatgccttca
     5461 gcgaaatgct gataggccgc agaggattga tcctgcgcta aatcacctgt cgcgacaatc
     5521 aggtcgaatt cgtgctggtg tggccgaatc gcctccagca ccgcctggta gctttcccag
     5581 gtgtttaccc ctaacagggc ttcgtgcttt tgtgcaaaca ggtgagtgtc ggtaatttgt
     5641 aaaatcctga ctctggcctc accagccaga ggaagggtta acaggctttc caaatggtgt
     5701 ccttaggttt cacgacgcta ataaaccgga atcgccatcg ctccatgtgc taaacagtat
     5761 cgcaaccagt ccgctaaaaa ctgattaatt tgatgctttt cgtcgcgttg atgcaacttt
     5821 ttattaggat aatcataccg cgctttgaag cgaaaaatct gctggcttga acacacttca
     5881 gccaccatcg cgtcatgata cagacgcacc gtcattgacg gaaggctcca gtaactgatc
     5941 gcgggcgcag tctgttctat tgtcaccagg gtagtgtatc gggtcgattc cacaatcgtc
     6001 agccgatatt gtgcgtttgc cacctgatag cttacagttt cgccgggtgc gtcattgcgc
     6061 ggtaacaaac ggcgcaattg tgaaaagttc atctcgcaca ggcgcatcat ttcaggaaag
     6121 tcaggtgtgt aacgcttcat ttatgcccac tcatttttta acgcttgatg atgcagctgc
     6181 agccattgca aagcgatgac cgacgctgcg ttgtcgattt tcccctcttc tacccactgg
     6241 tatgcctgtt cccggcttac cacatgaacg cgaatatctt cgttttcatc agccagaccg
     6301 tgaataccgc ttgcggtcgt ggcgtccact tcgcccacca taattgacga acgctcactg
     6361 gtgccccccg ggcttgccag gaaacttaac accggtttgg tccgtttgac tatcagtccc
     6421 gcctcttcaa tcgcttcgcg acgggcaaca tcttccacac tttcaccctc ttcaatcatc
     6481 ccggcaacca tctccagtag ccaaggggtt tcgctggtgt cgtacgcggc aatccgaatc
     6541 tgctcaatca gcacaacttc atcacgcact gggtcaaagg gtagcaagac tgcggcgtga
     6601 ccgcgctcaa aaatttcccg ccgtacctca tgactcattt gcccgttgaa tagacgatga
     6661 cgaaatctat aaagatctaa tgaaaaaaag ccgcgataaa gtgtttctcg tgcaataatt
     6721 tctacatcgt ttttgccaaa tgtaacgggc aggttgtctg gcttaagcat tgttaatgtc
     6781 ctggcactaa tagtgaatta aatgtgaatt tcagcgacgt ttgactgccg tttgagcagt
     6841 catgtgttaa attgaggcac attaacgccc tatggcacgt aacgccaacc ttttgcggta
     6901 gcggcttctg ctagaatccg caataatttt acagtttgat cgcgctaaat actgcttcac
     6961 cacaaggaat gcaaatgaag aaattgctcc ccattcttat cggcctgagc ctctctgggt
     7021 tcagttcgtt gagccaggcc gagaacctga tgcaagttta tcagcaagca cgccttagta
     7081 acccggaatt gcgtaagtct gccgccgatc gtgatgctgc ctttgaaaaa attaatgaag
     7141 cgcgcagtcc attactgcca cagctaggtt taggtgcaga ttacacctat agcaacggct
     7201 accgcgacgc gaacggcatc aactctaacg cgaccagtgc gtccctgcag ttaactcaat
     7261 ccatttttga tatgtcgaaa tggcgtgcgt taacgctgca ggaaaaagca gctgggattc
     7321 aggacgtcac gtatcagacc gatcaacaaa ccttgatcct caacaccgcg accgcttatt
     7381 tcaacgtgtt gaatgcgatt gacgttcttt cctatacaca ggcgcaaaaa gaagcgatct
     7441 accgtcaatt agatcaaacc acccaacgtt ttaacgtggg cctggtagcg atcaccgacg
     7501 tgcagaacgc ccgcgcacag tacgataccg tgctggcgaa cgaagtgacc gcacgtaata
     7561 accttgataa cgcggtagag cagctgcgcc agatcaccgg taactactat ccggaactgg
     7621 cggcgctgaa tgtcgaaaac tttaaaaccg acaaaccaca gccggttaac acgctgctga
     7681 aagaagccga aaaacgcaac ctgtccctgt tacaggcgcg tttgagccag gacctggcgc
     7741 gcgagcaaat tcgccaggcg caggatggtc acttaccgac tctggattta acggcttcta
     7801 ccgggatttc tgacacctct tatagcggtt cgaaaacccg tggtgccgct ggtacccagt
     7861 atgacgatag caatatgggc cagaacaaag ttggcctgag cttctcgctg ccgatttatc
     7921 agggcggaat ggttaactcg caggtgaaac aggcccagta caactttgtt ggtgccagcg
     7981 agcaactgga aagcgcgcat cgtagcgtcg tacaaaccgt acgttcctcc ttcaacaaca
     8041 ttaatgcttc tatcagtagc attaacgcct acaaacaagc cgtagtttcc gctcaaagct
     8101 cattagacgc gatggaggcg ggttactcgg tcggtacgcg taccattgtt gatgtgttgg
     8161 atgcgaccac cacgctgtac aacgctaagc aagagctggc aaatgcgcgt tataactacc
     8221 tgattaacca gttgaatatt aagtcagctc tgggtacgtt gaacgagcag gatctgctgg
     8281 cactgaacaa tgcgctgagc aaaccggttt ccactaatcc ggaaaacgtt gccccgcaaa
     8341 cgccggaaca gaatgctatt gctgatggtt atgcgcctga tagcccggca ccagtcgttc
     8401 agcaaacatc cgcacgcact accaccagta acggtcataa ccctttccgt aactgacgac
     8461 gacgacgggg cttcggcccc gtctgaacgt aaggcaacgt aaagatacgg gttatctgcc
     8521 gcattcttcc cccttctcgc ttcaatttcg accagccatc ctctattctg atgggtattt
     8581 accactggtc ccggaagaca aaaatgaaac ggacaaaatc catacgccac gcatcgttcc
     8641 gcaaaaactg gagcgcacgc catctgacac cagtcgctct cgcggttgcc actgttttta
     8701 tgctggcggg ctgtgaaaag agtgatgaaa cagtgtctct ctatcaaaat gctgacgact
     8761 gttcagctgc aaacccaggc aaaagcgccg aatgtaccac cgcgtacaac aatgcgctga
     8821 aagaagccga acgtactgcg ccgaaatacg ccacccgtga agactgtgtt gctgaatttg
     8881 gtgaaggtca gtgccagcag gcaccagccc aggctggcat ggcaccagaa aaccaggcgc
     8941 aggcccagca atccagcggg agtttctgga tgccgctgat ggccggttac atgatgggac
     9001 gtctgatggg cggcggcgcg ggatttgcac agcagccgct gttctcctcg aaaaacccgg
     9061 ccagcccggc ttacggtaaa tataccgacg cgaccggtaa aaactatggc gcagcccagc
     9121 caggccgcac catgaccgta ccgaagacgg caatggcacc aaaaccggcg accactacta
     9181 ctgttacccg tggcggtttt ggtgaatctg ttgccaaaca aagcactatg cagcgtagcg
     9241 caaccggcac ctcttctcgt tcaatgggtg gctgataccg atggaaagag tcagtattac
     9301 cgagcgcccg gactggcgcg aaaaagccca cgaatacggt ttcaattttc acaccatgta
     9361 cggcgagccg tactggtgtg aagatgctta ctacaagttg accctctctc aggttgaaaa
     9421 gctggaagaa gtcaccgccg aactgcacca gatgtgcctg aaagtggtgg aaaaagtgat
     9481 cgccagcgat gagctgatga ccaaattccg cataccaaaa cacacctgga gttttgtgcg
     9541 ccagtcatgg ctgacgcacc agccatcgct ttattcgcgt cttgatctgg cgtgggatgg
     9601 cactggcgaa cctaaacttc tggaaaataa cgccgatacg ccaacgtcac tatacgaggc
     9661 ggcgttcttt cagtggatct ggctggaaga tcagcttaac gccggtaact tgccggaggg
     9721 cagcgaccag tttaacagtc tgcaagaaaa gctgatcgat cgcttcgttg agctgcgtga
     9781 acagtatggc ttccagttgc tgcatctcac ctgctgtcgc gacacggtgg aagatcgcgg
     9841 aaccattcag tatttgcagg actgcgcaac ggaagctgaa atcgccaccg agttcctcta
     9901 cattgacgat atcgggttag gtgaaaaagg tcagttcacg gatttacagg atcaggtgat
     9961 ttccaacctg ttcaagctgt atccgtggga atttatgttg cgtgagatgt tctccaccaa
    10021 gctggaggat gcaggcgtac gctggctgga accggcgtgg aagagcatta tctccaacaa
    10081 agcgcttcta ccgctactgt gggagatgtt cccgaatcac ccgaacctgc tgcccgctta
    10141 ttttgcggaa gatgatcatc cgcaaatgga aaaatatgtg gttaaaccga tcttctcccg
    10201 tgaaggcgca aacgtgtcga tcattgagaa cggcaaaacc attgaagcag cggaaggtcc
    10261 gtatggcgaa gaagggatga ttgttcagca attccacccg ttaccgaaat tcggcgacag
    10321 ctatatgctg attggtagct ggctggtgaa cgatcaacct gccggaattg gcattcgtga
    10381 agaccgtgca ttgatcaccc aggatatgtc tcggttttat ccacatattt ttgttgagta
    10441 atacagctta atattgcccc gataagcggg gcaatctctt ataatccacc attcataatt
    10501 cccatcaata tata
//
LOCUS       DAFGPF010000156        10487 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFGPF010000156 DAFGPF010000000
VERSION     DAFGPF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10487
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.156"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(48..497)
                     /locus_tag="LSX49_004603"
     CDS             complement(48..497)
                     /locus_tag="LSX49_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170901.1"
                     /translation="MQRQYKKYILLFWGVMDVIAIATYLFYSLGNGRIPFYSDIVHSL
                     SLLKDIGVEGGFYAYAVATVTLQIVLLFSLFFSAQCFLRQKLFSFSFLAIQEFMRFAT
                     VSCSISVIPLLLNYFYSQDLVLNISLFIFSEVTKVTTIIWCKRQGKV"
     gene            complement(918..4601)
                     /gene="metH"
                     /locus_tag="LSX49_004604"
     CDS             complement(918..4601)
                     /gene="metH"
                     /locus_tag="LSX49_004604"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBL7170902.1"
                     /translation="MSSKVEQLCAQLNERILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVISAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPAEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPTELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANTQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKMLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKVSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     HRKGMSVTEVERWLAPNLGYDAE"
     gene            4802..5626
                     /gene="iclR"
                     /locus_tag="LSX49_004605"
     CDS             4802..5626
                     /gene="iclR"
                     /locus_tag="LSX49_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HBL7170903.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSNHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDRVTEFGAMVIKAAKEVTLAYGGIR"
     gene            complement(5643..7367)
                     /gene="aceK"
                     /locus_tag="LSX49_004606"
     CDS             complement(5643..7367)
                     /gene="aceK"
                     /locus_tag="LSX49_004606"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HBL7170904.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMAL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRR
                     QRFSVRFV"
     gene            complement(7492..8796)
                     /gene="aceA"
                     /locus_tag="LSX49_004607"
     CDS             complement(7492..8796)
                     /gene="aceA"
                     /locus_tag="LSX49_004607"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HBL7170905.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(8826..10427)
                     /gene="aceB"
                     /locus_tag="LSX49_004608"
     CDS             complement(8826..10427)
                     /gene="aceB"
                     /locus_tag="LSX49_004608"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HBL7170906.1"
                     /translation="MTEQATTIDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGRLPDFISETASIRDADWKIRGIPADLEDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEERNNQVLDKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
BASE COUNT         2462 a         2872 c         2612 g         2541 t
ORIGIN      
        1 aaaaaggcat ttatataaaa atccacctgt atctgttgct atttctgtca cactttcccc
       61 tgtcgtttac accagataat cgttgtcact tttgtgacct ctgagaagat aaacaacgaa
      121 atatttaaga ccagatcctg tgaataaaaa taattaagta acaacggtat tacggagatt
      181 gaacagctta cggtagcaaa acgcataaac tcctgaatcg ccaaaaaaga gaaactaaat
      241 aatttttgtc ttaaaaaaca ttgcgcagaa aagaataaag agaacaataa tactatttgt
      301 agcgtaacag tggcgactgc ataagcgtaa aaaccgcctt caacaccgat atccttaagt
      361 aaagaaagtg aatgaacgat atcggaataa aaagggatac gaccattacc aagcgagtag
      421 aacagatatg tggctatcgc gataacatcc ataacacccc aaaaaagaag aatgtatttt
      481 ttatattgac gttgcataaa gtaaatcctt tttacgaaaa caaatattac caggaattat
      541 tataattgcg ggcgtttttg gattaacact ccacccgtat tttttaaacc tctgtcagct
      601 ataccttcac taaataagac atcgatacgc cctttacttt tatcgtgata cagaatactg
      661 catgagatac accttatacc ctctttggat ttacgaaaat ctaaccaata acgaccatca
      721 taaaataccc actccacacc tgttttatat taattatcca atcattataa cctgttggtt
      781 ttttcctaat agttcagtaa cttcggactc tgaacatcct tcgaaagcga aaaaatctat
      841 ttcatcaatt tttatcatat tcaataatcc attatttatg acattaaaaa ccggggcaaa
      901 taccccggtg ttatcactta ctcggcatca taccccagat tcggtgccaa ccaacgctca
      961 acttcggtaa cgctcattcc tttacggtgg gcatagtctt caacctgatc gcgctgaatt
     1021 tgcgccaccg cgtaatactt gctgtctgga tgactgaagt accaacccga aaccgatgca
     1081 cccggccaca tggcgaaaga ttccgtgagt ttcataccgg tatgtttttc cacttccagc
     1141 agctcccaga ttgtggcttt ttccgtatgt tccgggcagg cagggtagcc cggtgccgga
     1201 cggatgccct ggtagttttc gcggatcagc tcttcgttgc tgaggttctc gttcggcgca
     1261 tagccccagt agactttacg cacacgctca tggagatact ccgcaaaggc ttccgccaga
     1321 cggtcggcaa gcgctttcac catgattttg ttgtaatcat catgctgtgc ttcaaaggca
     1381 tcagccagtg cgtcctcttc cagcccgcca gtcacggcaa atgcgccgat gtaatccgct
     1441 ttgccggaaa ccttcggcgc aacgaagtca gcgagacagt agttagcgaa gccggttttt
     1501 tcggtctgtt ggcgcagatg gtggctgaca ttaatcacat gggtacgcgt ttcgtcacgg
     1561 tagatttcaa tgtcatcgcc cacacggttt gccgggaaca ggcccaccac accacgcggg
     1621 ttcagcattt tttcggcgct taatttatcc agcatgtcgt tggcgtcttt aaacagccgc
     1681 tgcgcctcaa cacctaccac ttcatcttcc agaatgcgcg gatacttccc ggccagcgac
     1741 caggtcataa agaacggcgt ccagtcgatg taattacgca gcgtttcgat gctggcttcg
     1801 acttcctgca caccgagacg gtgcgccacc ggcggcgtgt aagcctgcca gtcaaaagcg
     1861 aagtcgttat cacgcgccgc ttccagcgtg accggtggtg tgcgtggttt ctttcgtccg
     1921 tgctgaatac gcacggtttc gtactccttg cgggtacgag caacgaaatc atcgcgctga
     1981 gtgtcggaaa gcagcgccgc caccacacca acggtgcgcg atgcgttctg cacatacacc
     2041 gtcgggccgc tgtagttctg ctcgattttc accgccgtgt gcgcttttga ggtggtcgcg
     2101 ccgccaatca atagcggaat ggtgaagccc tggcgctcca tctctttcgc cacgttaacc
     2161 atctcgtcca gcgacggcgt gatcagcccc gaaaggccaa tcaaatcagc attcacttct
     2221 ttagcggtac ggagaatttt ttccgcaggc accatcacgc cgagatcgac aatttcgtag
     2281 ttgttacatt gcagcaccac gccaacgata tttttaccga tgtcgtggac atcgcccttc
     2341 actgtggcga tcaccatctt gccgttggtt ttaccctgct ctttgctggc ttcaataaac
     2401 ggctcgagat acgccaccgc ctgcttcatt acgcgcgccg atttcaccac ctgcggcagg
     2461 aacattttgc cctcgccaaa caggtcgccg accacgttca tgccgtccat caacgggcct
     2521 tcaatcactt caatcgggcg cgtagcctgc tggcgggctt cttcggtatc ctgctcgata
     2581 aactcggtaa tgcctttgac cagcgagtat tccagacgtt tattcacttc ccacgagcgc
     2641 cactccgcct gctgggtgtt agcggtgtcg tcggttttgc tgccgcgata tttctcggca
     2701 agctcgagta aacgctcggt gccatcgtcg cggcggttga ggatcacatc ctccaccgcg
     2761 tcgcgtagct cggtaggcag gtcgtcgtaa atcgccagtt gcccggcgtt gacgatcccc
     2821 atatccatgc cattgcgaat agcgtagtag aggaacaccg cgtgaatggc ttcgcgcaca
     2881 ggatcgttac cacgaaacga gaacgacacg ttagaaacgc cgccggaaat cagtgcgtgc
     2941 ggcagttcac gtttgatgtc ttcacacgcg ccgataaagt cctgtgcgta attgttgtgc
     3001 tcttcaatgc cagttgcgac cgcgaagatg ttcgggtcga agatgatatc ttcagccggg
     3061 aagccaacct cttcggtgag gattttgtac gcccgacggc aaatctcgat tttccgtgcg
     3121 cgggtatcgg cctggccctg ttcgtcaaaa gccattacca ctactgccgc accgtagcga
     3181 cgcaacagtt tcgcgtgatg gataaaggcg tcgacgccct ctttcatcga gatagagtta
     3241 acaatgcctt tgccctggat acacttcaga cctttttcaa taacgtccca tttcgaggag
     3301 tcgatcatta tcggcacacg agcgatatcc ggttcaccgg caatcagatt gagaaaacgc
     3361 accatcgccg cttcggcatc gagcatccct tcatccatgt tgatatcgat aatctgcgca
     3421 ccgttttcca cctgctgacg cgccacatcc agcgcctcgc tgtatttctc ttctttgatc
     3481 aggcgcttga acttagcgga accggtgacg ttggtgcgtt cacccacgtt cacaaacagg
     3541 ctatcttcgc caatgttcag cggctccagg ccggacaaac ggcaggctac gggaatttcc
     3601 ggtagtttgc gcggcgctaa tccttctact gcacgactca tcgctgcaat atgttgtggc
     3661 gtggtgccgc agcagccgcc gacgatattg agaaagcccg cttctgccca ttcacgtatc
     3721 tgttttgcca tcgtgtcggc gtcgagatcg tattcaccaa aggcgttggg cagcccggcg
     3781 ttcgggtggg cggtgacata gcattccgca atacgcgaca gttcctgtac gtactggcgc
     3841 agttcgtctg gccccagcgc acagttcagg ccaaaggtca gcgcttcggc gtggcgcagg
     3901 gagttgtaaa acgcttcagt ggtctgcccg gagagcgtgc gcccggaggc gtcggtgatg
     3961 gtgccggaga tcataatcgg cagttcaacg cccagcgctt caaactccgt tttcaccgca
     4021 aagaccgccg ctttggcgtt aagggtgtcg aaaacggttt caatcaggat caggtccgcg
     4081 ccaccttcca ccagcgcttt ggtggattct cgataagccg ccaccagctg gtcaaaagtg
     4141 atgttgcgga atgccggatc gttgacgtcc ggagaaatag acgccgtgcg gttggtcggg
     4201 ccgagaacac cggcaacgta gcgcggtttc tccggcgtgc gggcagtcca ctcgtcggca
     4261 caggcgcgcg ccagtttcgc cgccgcaaag ttgatttccg ccgacaggga ttccatctgg
     4321 taatccgcca tcgcaatagt cgtggagttg aaggtgttgg tttcgatgat atccgcaccc
     4381 gcttcaaagt aagcgttgtg gatggcggag atcacttccg gtttgctgag caccagcagg
     4441 tcgttgttgc ctttgagatc gcatggccag tcggcaaagc gttcaccacg aaaatcggct
     4501 tcgttcagtc gatagctctg gatcatggtg cccataccgc cgtccagcac cagaatacgt
     4561 tcatttaact gcgcacacag ttgttccact ttgctgctca cacttgctcc cgacacgctt
     4621 aacccagatt taataaaaat tcaacaaacc atactggcat aaacacatct gtggtaaaag
     4681 cgaccaccac gcaacatgag atttgttcaa cattaactca tcggatctgt tcagcaacta
     4741 ttgcattcgc tgataataaa aatgaaaatg atttccacga tacagaaaaa aggagactgt
     4801 catggtcgca cccattcccg caaaacgcgg cagaaaaccc gccgttgcca ccgcaccagc
     4861 gactggacag gttcagtctt taacgcgtgg cctgaaatta ctggagtgga ttgccgaatc
     4921 caatggcagt gtggcactca cggaactggc acagcaagcc gggttaccca attccacgac
     4981 ccaccgcctg ctaaccacga tgcagcaaca gggctttgtc cgtcaggtcg gcgaactggg
     5041 tcactgggcg atcggcgcac acgcctttat ggtcggcagc agctttctcc agagccgtaa
     5101 tttgttagcg attgttcacc ctatcctgcg caatctaatg gaagagtctg gcgaaacggt
     5161 caatatggcg gtgcttgatc aaagcaatca cgaagcgatt attatcgacc aggtacagtg
     5221 tactcacctg atgcgaatgt ccgcgcctat cggcggtaaa ttgccgatgc acgcttccgg
     5281 tgcgggtaaa gcctttctgg cccaactgag cgaagaacag gtgacgaagt tactgcaccg
     5341 caaagggtta catgcctata cccacgcaac gctggtgtct cctgtgcatt taaaagaaga
     5401 tctcgcccaa acgcgcaaac ggggttattc atttgacgat gaggaacatg cgctggggct
     5461 gcgttgcctt gcagcgtgta ttttcgatga gcaccgcgaa ccgtttgccg caatttcaat
     5521 ttccggaccg atttcacgta ttaccgatga ccgcgtgacc gagtttggcg cgatggtgat
     5581 taaagcggcg aaggaagtga cgctggcata cggtggaata cgctgacttt ttcgcctctg
     5641 atttatacga atcgaacgct aaaccgctgc ctgcgccgat acgcataaac atcttccaca
     5701 tgcccttcac gtatacggtt ttgtagtgcg cgccagtaat cagcgcggaa caagtcggcg
     5761 tgcatctctt caaatagcgg accaatacgc gggtcggcac ataaccagtg acggaactct
     5821 tccgggaaaa catcgcccgg cgagacgctg taccacggtt cgctggcaag ttcgtcctcc
     5881 gggtagcgcg gcggcgggat gtcgcggaag ttcacttccg tcatgtagca aatttcatcg
     5941 taatcataaa acaccacacg cccgtgacgg gtgacaccga agtttttaaa cagcatgtcg
     6001 ccagggaaaa tgttagcagc ggcaagctgg cgaatagcgt taccgtattc ttcaatggca
     6061 tcgcgcaact gctgaccttc cacttgttcc agccagatat tgagcggcac catccgccgc
     6121 tcaatataaa gatggcgaat cacaatttgt tcgccgagat cggtgatttt ttccgctgct
     6181 tcctggagca gtaatgccat taatgccggg gaaatatgcc gcttctccag cacaaagttt
     6241 tcaaactcct gggtgtccgc cattcggccc acgcgatcgt gctctttcac cagttggtag
     6301 caggcgcgaa cgtgagcggc agacatctct ttctgcggcg cgaacttgtc tttgatcact
     6361 ttaaataccc ggtcaaagcc cggcagcgtg aacaccaaca tcaccattcc acgaataccc
     6421 ggcgcttcaa tgaactgctc attacagccc tgtagataaa cgagatattc gcggtagctt
     6481 tcggttttgg cgtgcttctg gcagccgata gccatataca attcagcggt ggttttacct
     6541 ggcagaattt cccgtagcca ctcgaccagc gctgcgggca gcggcgcgta aaccataaaa
     6601 taagaacgcg caaagccaaa gacgatgctc gcttcggcgg tcgtcgtcag acaggtatca
     6661 ataaataact cgccgtcgtc cgtctggtgg atcggcagca aaaatggcaa tgtgccggaa
     6721 ggcgtgatca gtttgcccac cagccaggcg gctttattgc ggtaaaacag ttcgttcgcc
     6781 acctgtaaat gactttccgc gaggttgtct gtccccagcg tttccgttag atggcgaacg
     6841 atgtaatgaa tgtcacggct tttattctgc cagcgcagac gcaacggcag gtcgctgata
     6901 acgcgcatca gcagagattc ccagccgtga tcggggtgaa agtctttcgc cagcgggcgg
     6961 ggaatggtac gaaaacggcg ctctggctgg gagctaaaga taaaaagccg ctcgggagta
     7021 agcgagcggt ggtcaaataa ccgacagtac acggagttaa aaaagctctc cgcaatctcg
     7081 aagcgcgggt aatccggcaa cagtcgggtg taatgctctt taacgcgcag taaaaatgcc
     7141 gcgtccgtgc tttggccgtt agtaatgcag cgcagttgct ccacaaccag acccacgtga
     7201 tgatcgtaaa gatggatacg gtttttcatc gcttgctgga cagcgtgcca gtcggcttgt
     7261 tcgaaacgct gctgcgcccc ggaagtcact tcgaggaatc gaccatactg agcgtcgaag
     7321 ccttgcagaa tggtttgtgc aatcagtaat tccaggccac gcggcattta gcgccctcat
     7381 caggagcaga gaattgccgg ataagacgcg caaatcgtcg catcaggcgt tgattgccgg
     7441 atgcggcgtg aacgccttat ccggcctaca atcatcaact ttatcagttg cttagaactg
     7501 cgattcttcg gtggagccgg tcagcgcggt gactgaagac gtgccgccct gaataatggt
     7561 cgtcacttta tcgaaataac ctgtccccac ttcctgctgg tgagatacga aggtatagcc
     7621 atctttcgcg gcggcaaatt ccggctgctg cactttctca acatagtgct tcataccctc
     7681 accctgggca taggcgtttg ccaggtcaaa catgttgaac cacatgctgt ggatacctgc
     7741 cagggtgatg aactggaact tgtagcccat atccgacagc tgctgctgga agctggcaat
     7801 agttttgtcg tcgaggtttt tctgccagtt gaacgacggc gagcagttat aagccagcag
     7861 tttgcccgga tatttcgcgt ggatggcttg tgcaaagcga cgcgccagtt ccagatccgg
     7921 cgtggaggtt tcacaccata ccaggtcagc atatggcgca tacgccaggc cacggctgat
     7981 cgcttgctca atacccgcat gagtacggaa gaagccttca ctggtacgct cgccagtaat
     8041 aaattcgctg tcatatgggt cgcaatcgga ggtaatcaga tccgccgcat cggcatcggt
     8101 acgagcaacc agcagggttg gaacgcccgt cacatcagct gccagacgcg ccgcgaccag
     8161 tttctgaata gcttcctgag ttggcaccaa aactttgccg cccatgtgac cacatttctt
     8221 cactgatgcc agctgatctt cgaagtgaac tgccgctgca ccggcttcaa tcatcgcttt
     8281 catcagttca aaggcattca gtacaccgcc aaaaccggcc tccgcatcgg cgacgatcgg
     8341 caggaagtaa tcgacatagc gcggatcgcc cggctcaatg cccgcggacc attggatctg
     8401 atccgcacgg cggaaagtat tgttgatccg ctctaccaca gctggcaccg agtttgccgg
     8461 atagagcgac tgatccggat acatgctggc cgccaggtta gcgtccgccg ctacctgcca
     8521 tcccgacaga tagactgctt caatacccgc tttcgcctgt tgcaacgcct gaccgccagt
     8581 cagtgcaccg aggctgttga tgtagccttt tttcgactcg ccgtgcagca gacgccacat
     8641 tttcgccgcg cccagttgcg ccagggtgca ttccggattg actgaaccgc gtaatttcac
     8701 cacatcttcc gcgctgtacg ggcgagtaat gccttcccaa cgcggttgag tccactcttt
     8761 ctgtaattct tcaatttgtt gtgtacgggt tttcatgtgc agatgctcca tagttatgtg
     8821 gtggtttacg ctaacaggcg gtagcctggc agggtcagga aatcaattaa ctcatcggaa
     8881 gtggtgatct gttccatcaa gcgtgcggca tcgtcaaaac gcccctggga gaaacgttct
     8941 tcgcccagtt cgctggcaat gactttcatc tcttcgccca gcatctggcg gaacaaggct
     9001 ttagtcaccg gtttgccatt gctcaacgtt ttttgatgat ggatccactg ccagattgag
     9061 gtacgggaaa tttcagccgt cgccgcatct tccatcaggc cataaatcgg cacacagcca
     9121 ttgccagaga tccacgcttc gatgtactgc acagccacgc gaatgttggc acgcatacct
     9181 tcttcggtgc gttcaccatc acaaggtgcc agcagctgat cggcagtaat cggcgcgtct
     9241 tgttcgcgca tcacctcaag ctggtttttg cgggagccga gaatatcgtt gaataccgcc
     9301 attgccgtat cagcaaggcc cgggtgagcg atccatgtgc catcgtgacc gttattggct
     9361 tccagcgatt tatccgcttt tactttgtcg agcacctggt tattgcgctc ttcatctttg
     9421 ctcggaataa acgccgccat gccgcccatc gcaaaagcac cgcgtttatg gcaggtttta
     9481 atcaacaggc gtgagtaagc attcaggaag ggtttatcca tcgtcactgc ctgtctgtct
     9541 ggcaggacgc gatcgggata gtttttcaat gttttgatat aactgaagat gtaatcccaa
     9601 cgaccgcagt tcagaccaac aatatggtca cgcagcgcgt gaaggatttc atccatctgg
     9661 aacacggcgg gcagcgtttc aatcagcaac gtcgccttga tggtgccgcg cggcagatta
     9721 aagcgatctt ctgcatagct gaagacttcg ctccaccagg ccgcttcctg ccaggactgg
     9781 gttttcggca gatagaaata gggaccgctg ccctttgcca acagtgcctg atagttgtgg
     9841 aagaaataga gcgcaaaatc aaacaggcta ccggggattg cctcaccacg ccaggtgaca
     9901 tgtttttccg gcaagtgcag accgcgtacc cgacaaatca aaaccgctgg attgggcttg
     9961 agctgataaa ttttgcctgc ttcattggta tagctgatgg tgccgttaac tgcatcgcgc
    10021 aggttaattt gcccatcgat cactttgttc cagtctggtg ccagtgaatc ttcgaaatcg
    10081 gccataaaga ctttcacatt ggcgttgagc gcgttgatca ccatcttgcg ctctacaggt
    10141 ccggtaatct ctacgcgacg atcttctaag tccgcaggaa tcccgcgaat tttccagtca
    10201 gcatcacgaa tggaagctgt ttccgaaatg aaatcaggca accttccgtt atcgatatcc
    10261 tgctgctgct gaatgcgcgc tgccagaagt ttattgcgtt gtggcgtaaa atgcgtcacc
    10321 agctcagtca gaaattctac cgcttcggca gtaagaattt gcttctcctg ctcgccatac
    10381 ggccttgtga aagccagttc atcgattgtt gttgcctgtt cagtcatcgt gcagctcctc
    10441 gtcatggatc cgaaaacttc cccactgtga acgaaggatc gttgtgc
//
LOCUS       DAFGPF010000157        10454 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFGPF010000157 DAFGPF010000000
VERSION     DAFGPF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10454
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.157"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..603
                     /locus_tag="LSX49_004609"
     CDS             <1..603
                     /locus_tag="LSX49_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL7170907.1"
                     /translation="LLYDNPSLSNSDIQLLATNQLISYHVVLNNKMLPNQCALLPLSK
                     LIIISDNFRKLAKNADYNGPELFTHAHQFVGQNYLGFGDYTITGQVLDLGGGQPSAVA
                     AHLVFKNLQANTVWIRHFVSSNTQRGSSNVTAKFLDVSDQITNLVPQHPTQFGSNIGL
                     NYYYYNSQPTVRHFPGLPKNKQYQITHHICFMLDLIAGRI"
     gene            complement(583..1758)
                     /locus_tag="LSX49_004610"
     CDS             complement(583..1758)
                     /locus_tag="LSX49_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL7170908.1"
                     /translation="MLLSDIQIKRAKPKDKPYTLNDGMGLSLLIDTAGSKGWRFRYRF
                     AGKPKMISFGVYGDVSLAQARTKRDEARSMLANGINPSEARKADKIALQFAHENSFES
                     VAREWHSSKKATWSEGYAKEVLNCMEKDIFPFIGQRPIEQIEPLELLTVLQKIEKRGA
                     LEQTSKIRRRCGEVLRYAVATGRAKYNFAPDLAIALNKPKTQHFPFLTESELPEFVNA
                     LDNYQGSLVTKYATQLLMLTGVRTIELRAAEWAEFDLDNALWEIPKERMKKRRPHLVP
                     LSTQAINILKKLQEITGNYSLVFPGRNDVSKPMSEASINKVIKLLGYHGRLTGHGFRH
                     TMSTILHEHGFESAWIEMQLAHVDKNSIRGTYNHAQYIKDRQVMMEWYASLLNTTCY"
     gene            complement(1919..1993)
                     /locus_tag="LSX49_004611"
     tRNA            complement(1919..1993)
                     /locus_tag="LSX49_004611"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1958..1960),aa:Arg,seq:cct)
     gene            complement(2069..3001)
                     /locus_tag="LSX49_004612"
     CDS             complement(2069..3001)
                     /locus_tag="LSX49_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBL7170909.1"
                     /translation="MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGIVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA"
     gene            3295..4050
                     /gene="mlaA"
                     /locus_tag="LSX49_004613"
     CDS             3295..4050
                     /gene="mlaA"
                     /locus_tag="LSX49_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HBL7170910.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
                     DGGDMADSLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
     gene            complement(4112..5452)
                     /gene="fadL"
                     /locus_tag="LSX49_004614"
     CDS             complement(4112..5452)
                     /gene="fadL"
                     /locus_tag="LSX49_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416846.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HBL7170911.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVDITGHSNLTGQSANAKNIAPT
                     AWVPNLHFVAPINDQFGWGASITSNYGLATEFTDNYAAGIYGGKTDLQTINLNLSGAY
                     RLNNSWSFGLGFDAVYAKAKIERYAGSLGPLLSQQLIAQGVPASLTNGINTPDSQIAH
                     LKGDEWGFGWNAGILYELDKDNRWGLTYRSEVKIDFDGDYKSSINPNLNNILGNMGLP
                     YGTMGATQNGSLTLNLPEMWEISGYNRVAPQWAIHYSMAYTSWSQFQELKAKGDSGQT
                     LFYKDEGFRDAYRIALGTTYYYDKNWTFRTGIAYDDSPVPADKRSISIPDQDRLWLSA
                     GLTYAFNEDASIDVGASYMHGQKVKFTEGEGAAAYSFESEGKAWLFGTNFNYAF"
     gene            5824..6108
                     /locus_tag="LSX49_004615"
     CDS             5824..6108
                     /locus_tag="LSX49_004615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HBL7170912.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTL
                     AALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            6289..7599
                     /gene="fadI"
                     /locus_tag="LSX49_004616"
     CDS             6289..7599
                     /gene="fadI"
                     /locus_tag="LSX49_004616"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HBL7170913.1"
                     /translation="MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARTEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     EGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     GDLTLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDESKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            7599..9743
                     /gene="fadJ"
                     /locus_tag="LSX49_004617"
     CDS             7599..9743
                     /gene="fadJ"
                     /locus_tag="LSX49_004617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HBL7170914.1"
                     /translation="MEMASAFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEVLARQGQQLMAEIHALPI
                     PVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQAVKLGLVDDVVPHSILLEAAVELAKQDRPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRNIFFASTDVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLP
                     VRIKDINPQGINHALKFSWDQLEGKVRRRHLKASERDKQLALISGTTDYCGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNCATHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSP
                     VEKMPLVEIIPHASTSAQTIATTVKLAKKQGKMPIVVRDKAGFYVNRILAPYINEAIR
                     MLTEGERIEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIMPVLEAAYGERFSASANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGVQGQGRLSAPQVAERCVM
                     LMLNEAVRCLDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCDRLVEMSERGESFWKTTATDLQ"
     gene            9946..10431
                     /gene="sixA"
                     /locus_tag="LSX49_004618"
     CDS             9946..10431
                     /gene="sixA"
                     /locus_tag="LSX49_004618"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HBL7170915.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTHGCDESRLMANWLKGQKVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVGAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGKGQFNWQMSPCNLKMAKA
                     I"
BASE COUNT         2599 a         2471 c         2625 g         2759 t
ORIGIN      
        1 cttctatatg ataatccatc attatccaac tctgatattc agttgttggc gacaaatcaa
       61 ttgattagtt atcatgttgt tttaaataat aaaatgcttc ctaatcagtg cgctcttctt
      121 cctttgtcga agttaattat tattagcgat aactttagaa agttagcaaa aaatgctgat
      181 tataatgggc cggaactttt cacgcacgca catcaattcg tgggacaaaa ttacttagga
      241 tttggcgatt atacaattac tggccaggta ctagatcttg gaggtggtca accttctgct
      301 gttgccgcac atttggtgtt caagaattta caagcgaata cagtttggat tcgtcatttt
      361 gtatcaagca acacgcaacg aggaagttca aatgttactg caaaattttt agatgtttca
      421 gatcaaatta caaatcttgt tccccaacat ccaacccagt ttggcagcaa cattggtctt
      481 aactattatt attacaatag tcaaccaact gtaaggcatt tccctgggtt gccaaaaaac
      541 aaacagtatc aaattactca ccatatttgt ttcatgctgg atttaatagc aggtcgtatt
      601 taataagcta gcgtaccatt ccatcattac ttgtcgatct ttaatatatt gcgcatgatt
      661 gtaagtacct cgaatagagt tcttatcaac atgcgcaagc tgcatttcaa tccaggcact
      721 ttcaaaccca tgctcatgca agatggtgct catggtatgc ctgaaaccgt gacccgttaa
      781 ccgaccgtga taacccagta gttttatcac tttgttgatg ctggcttcgc tcattggttt
      841 actgacgtca ttccggccag ggaaaacgag gctgtaattc cctgttattt cttgcagctt
      901 tttcaggata ttgatcgcct gagttgataa cggaaccaga tgggggcggc gtttcttcat
      961 ccgttctttg gggatctccc ataaggcatt atctaaatca aactcagccc attccgctgc
     1021 acgtagttca attgttcgca cgcctgttag catcaacagc tgcgtggcgt atttggtaac
     1081 taaactgccc tgatagttat ccagagcatt aacgaactcg ggcaactcgc tttcagtcag
     1141 gaacgggaag tgttgggttt taggtttgtt gagtgcgata gctaaatcgg gtgcaaaatt
     1201 atactttgct ctaccagtgg caacagcata acgaagcact tcaccacagc ggcggcggat
     1261 cttactggtt tgctctagcg cacctctttt ctctattttt tgcaggacgg ttagcagttc
     1321 taatggttca atctgctcaa ttgggcgctg gccgataaaa ggaaaaatat ccttttccat
     1381 acaattgaga acctcttttg cataaccctc tgaccaggtg gcttttttcg atgagtgcca
     1441 ttctctggcc acagactcaa agctgttctc atgcgcgaac tgcaaagcaa tcttatctgc
     1501 ttttctggct tcacttgggt ttatcccgtt ggctaacatc gaacgcgctt catcacgttt
     1561 ggtacgtgcc tgtgccaacg acacatcgcc atatacgcca aaggaaatca tcttaggctt
     1621 acctgcaaag cgatagcgaa aacgccagcc tttactgccc gctgtgtcga tcaggagtga
     1681 tagccccata ccatcgttaa gcgtataggg tttgtccttc ggttttgctc tttttatttg
     1741 gatgtcagat agcagcatgt gtatagaaaa aagatcgaac tcagttatac acaatgttat
     1801 acgcaaagat gtatagattc cattagaaat aatggtactt tgctggacga gtataaggag
     1861 atgatatcag ttaaaacagt gagttatgga attaattgaa cttagtgaga agtgttcatg
     1921 gtgtcccctg caggaatcga acctgcaatt agcccttagg aggggctcgt tatatccatt
     1981 taactaagag gacaatgcgg catgagtata cccgctaatg gactacgggg taagtacaca
     2041 gccgctcgat tgcttaaacc ctcgccattt atgccgggtt tttatcattt ttcttaatgt
     2101 tttccgcacg ttctgctttt tgacgtgctt ctgctttgcg cttgttgctc atgtcgttac
     2161 gaatctgtgc atgactcatt aacgcgaaga taaaggtgcc gccgcagatg ttccccgcta
     2221 aagtaggtag tgcgaagggc cagatgaaat cgctccagtg cagcgtgccg ttaaacacca
     2281 gatagaggat ttcaacagaa ccgacaacga tgtgggtggt gtcacccagg gcaataagcc
     2341 aggtcatcaa tataatcacc acaatctttg ccgcacccgc tgcaggaaac atccatacca
     2401 tagtggcgat cagccagccg gaaataatcg cgttggcaaa catctcgctg ggggtgttct
     2461 tcatcacatc catgccgatt ttgacaaatg catcgcgagt ttcttcattg aagataggca
     2521 tatattcaaa tgcccacgca gcaatacctg tcccgagaat attacccagc agcacgatgc
     2581 cccataaccg cataagtaag ccgacgttgc tcattgtcgg tttttgcatg acgggtagta
     2641 ccgcagttac ggtgttttcg gtaaataatt gctggcgggc cattatgacg ataataaaac
     2701 caaaggtata accgagattc tccagcaaga agctgcccgg cacgccttcc agttcgacat
     2761 gaaatatccc ttttgccagt aacgaagcgc ccatcgacag gcccgccgca atggctgacc
     2821 acagtagcgc cattgcgtcg cgttccagct ctttttcacc atcctggcgg atatgctcat
     2881 gaattgccat cgcccgggag gggagtcggt cttcatctat ttctattttt ttaccgcgct
     2941 ctttttcttc gctctcaact tcaatttcgt cgctgtgttg atcaattttg tcgttgtcca
     3001 tggtctcttc tcttgaatta gcacgtatag ctaaagcgta gcggcttttt tgctcgcaac
     3061 tggcgggagt tactctgaaa atgtagaaaa ggccgcgttt gcctttttct gtttctattg
     3121 aatcaagtag cctacagggc ggcgattacc aggctatgat caaatcagca aatcagggcg
     3181 tctggacatc agttgacgtg ctgttacaat cgcccacacc taaacaggcg gatacggtat
     3241 cgttccgtca tggatggcaa actgcataag ccataaaaaa acagggagac atttatgaag
     3301 cttcgcctgt cggcgcttgc tctgggaact acgcttctgg tggggtgtgc gagttccggt
     3361 acagatcagc aagggcgttc tgacccgtta gaagggttta accgcactat gtacaacttc
     3421 aacttcaatg tattagaccc gtatattgtt cgaccggtcg ctgtcgcctg gcgtgattat
     3481 gttccgcaac ctgcgcgtaa cggtttgagc aactttaccg gcaaccttga agaacctgcg
     3541 gtgatggtta actacttctt gcagggcgac ccttatcagg ggatggtcca ctttacccgc
     3601 tttttcctga ataccatttt gggaatgggc ggctttattg atgttgcagg gatggcgaac
     3661 ccgaaactgc aacggactga acctcaccgc ttcggtagta cgcttggtca ttatggtgtg
     3721 ggttatgggc cgtacgttca gttaccgttc tacggtagct tcacgctgcg tgatgacggt
     3781 ggtgatatgg cggatagtct ttacccggtt ctttcctggc tgacctggcc gatgtctgtg
     3841 ggtaaatgga cgcttgaagg gatagaaact cgtgcgcagt tgttggattc cgacggtctg
     3901 ctgcgtcagt cctccgatcc ttatattatg gtgcgtgaag cgtacttcca gcgtcatgat
     3961 ttcatcgcta atggcggtga actcaaaccg caggaaaatc cgaacgcgca agcgattcag
     4021 gatgatttaa aagatatcga ttctgaataa gaaacaaaca aaaaaggtga gtcgcaaaac
     4081 tcaccttttt tcttattaag ctaacgcgtt atcagaacgc gtagttaaag ttagtaccga
     4141 acagccaggc tttaccttca gactcgaagg aataagctgc cgctccttca ccttcggtga
     4201 atttcacttt ctgaccatgc atataagatg cgccaacatc aatggatgca tcttcattaa
     4261 atgcgtaggt taacccagca cttaaccaca aacgatcctg gtcaggaatg gaaatagaac
     4321 gtttatctgc cggaaccggg ctgtcgtcat aagcgatacc ggtacggaag gtccagtttt
     4381 tatcataata gtaggttgta cccaacgcga tacgatacgc gtcccggaat ccttcatctt
     4441 tatagaacag agtctgacca ctatcgcctt tcgctttcaa ttcctggaac tggctccaac
     4501 tggtataggc catgctgtag tgaattgccc actgcggcgc aacacggtta taaccagaaa
     4561 tctcccacat ctcaggcagg ttcagcgtta aggatccatt ttgggttgcc cccatcgtgc
     4621 catacggtaa gcccatgtta cccaaaatat tgttcagatt tgggttaatg gagcttttgt
     4681 aatccccatc gaagtcgatt ttaacttctg aacgatatgt cagcccccaa cggttatctt
     4741 tatccagttc ataaagaata cccgcgttcc agccaaagcc ccattcgtca cctttcaaat
     4801 gagcaatttg agagtccgga gtattaatac cattggttaa tgaagcgggt acaccctggg
     4861 caatcaactg ttgagacaac aatggcccca gcgaaccggc gtaacgctca atttttgcct
     4921 tggcataaac tgcatcaaaa ccaagaccaa aactccagct attgttaagg cgataagccc
     4981 cgctaaggtt aaggttgatt gtttgcagat cggttttacc gccatagata ccagcagcgt
     5041 agttgtcggt aaattccgta gccaggccat agttggaagt tattgacgct ccccaaccaa
     5101 actgatcgtt aataggcgcg acaaagtgca ggttaggtac ccacgctgtc ggcgcgatat
     5161 ttttagcatt tgcactctga ccggttaaat tagaatgtcc ggtaatatct acatccggat
     5221 caatataaac cgcacccgca gaaaatgtcg ggcggtcaaa catggtaatc aatgcggggt
     5281 tacggctaac gttacctgca tcatcggcaa ttgcaccttc ccctgaataa gcccggccca
     5341 ggccagagga agaaaattcg tttaactgaa agcctgccga ccaggcctgg gtggagataa
     5401 gtgccactgc gactgcgaga gcagactttg taaacagggt tttctggctc atgaccataa
     5461 cctcaatgat ttatttttat acaaactatg ttacgtgctg taacaggagc gcgaagtgta
     5521 gggtctgagg tacatcttag aaatcagacc agtggcgaga gtataggtcg gaccagctgg
     5581 gatgttgcaa gtatgtttct atcttttttc agatatgatc taagaaacgc gatccagctg
     5641 gcaaaattgg gaggtggcgc actcatggat tcgggtgaat tttgttttag atcattttta
     5701 agtgtgattt cggtcactta tccgattttg cagaattaac aactggagca gcactttccg
     5761 gaagcgtaaa atatccacaa cgtttatctg gcaccttggg tgcacataca gaggaaatca
     5821 acgatgagta aatgtagtgc tgatgaaacc ccggtttgct gctgtatgga tgttggcacc
     5881 attatggaca actccgactg caccgcgtct tacagccgtg tgtttgcaaa ccgcgcagaa
     5941 gcagaacaaa cgctggcggc gctgactgaa aaagcccgta gcgtggaatc cgaaccgtgc
     6001 aaaatcaccc cgactttcac tgaagagtct gacggtgtgc gcctggatat cgatttcact
     6061 tttgcctgcg aagctgaaat gctgatcttc cagctgggtc tgcgttaatt cctctcgggt
     6121 acatacgccc ctgtcagctg ctgacagggg cgttttattt tctcctcctc ttttctctct
     6181 gtgtcatagc tcccactttc ccttttctcc acttggctaa atgtaaaaaa atggttaaga
     6241 ctatgatcag gtcagaccac tttatttatt tttttacagg ggagtgttat gggtcaggtt
     6301 ttaccgctgg ttacccgcca gggcgatcgt atcgccattg ttagcggttt acgtacgcct
     6361 tttgcccgac aggcgacggc ttttcatggc attcccgcgg ttgatttagg gaagatggtg
     6421 gtaggcgaac tgctggcacg caccgagatc cccgctgaag tgattgaaca attggtcttc
     6481 ggtcaggttg tgcaaatgcc ggaagcgccc aacattgccc gtgaaattgt tcttggcact
     6541 ggaatgaatg tgcatactga tgcttacagc gtcagccgcg cttgcgccac cagttttcag
     6601 gcggttgcga acgttgccga aagcctgatg gcgggaacta ttcgagcggg gattgccggt
     6661 ggggcagatt cctcttccgt attgccaatt ggcgtcagta aaaaactggc gcgcgtactg
     6721 gttgatgtca acaaagcccg cacaatgagc cagcgcctga aactcttctc tcgcctgcgt
     6781 ttgcgcgact taatgcccgt accgcctgcg gtagcagaat attctaccgg cttgcggatg
     6841 ggggacaccg cagagcaaat ggcgaaaacc tacggcatca cccgagaaca gcaagatgca
     6901 ctggcgcacc gttcgcatca gcgtgccgct caggcgtggt cagaaggtaa actcaaagaa
     6961 gaggtgatga ctgcctttat ccctccttat aaacaaccgc ttgtcgaaga caacaatatt
     7021 cgcggtaatt cctctcttgc tgattacgca aagttgcgtc cggcgtttga tcgtaaacac
     7081 gggacggtaa cggcggcgaa cagtacgccg ctgaccgatg gcgcggcagc ggtgatcctg
     7141 atgactgaat cccgggcgaa agaattaggg ctggtaccgc tgggctatct gcgcagctac
     7201 gcatttactg cgatagatgt ctggcaggac atgttgctcg gtccagcctg gtcaacaccg
     7261 ctggcgctgg aacgtgccgg attgacgatg ggcgatctga cattgatcga tatgcacgaa
     7321 gcctttgccg cccagacgct ggccaatatt cagttgctgg gtagcgaacg ttttgctcgc
     7381 gacgtactgg ggcgtgcaca tgccactggc gaagtggacg agagcaaatt taacgtgctt
     7441 ggcggttcga ttgcttacgg gcatcccttc gcagcgaccg gcgcgcggat gattacccag
     7501 acattgcatg aacttcgccg tcgtggcggt ggatttggtt tagtgaccgc ctgtgctgcg
     7561 ggtgggcttg gcgcagcaat ggttctggag gcggaataat ggaaatggca tcagcgttta
     7621 ctcttaatgt tcgtctggac aacattgcta tcatcaccat cgacgtaccg ggtgagaaaa
     7681 tgaataccct gaaggcggaa tttgcctcgc aggtacgcgc cattattaag caactccgtg
     7741 aaaacaaaga gttgcgtggc gtggtgtttg tctccgcgaa accagacaac ttcattgctg
     7801 gcgcagacat caacatgatc ggcaactgca aaacggcgca agaagcggaa gtactggcgc
     7861 ggcaggggca acagttaatg gcggagattc atgctttgcc cattccggtt atcgcggcta
     7921 ttcatggcgc ttgcctgggc ggcgggctgg agttggcgct ggcgtgccac ggtcgtgttt
     7981 gtactgacga tcctaaaacg gtgctcggtt tgcctgaagt acaacttgga ttgttacccg
     8041 gttcaggagg tacccagcgt ttaccgcgcc tgataggtgt cagcacagca ttagagatga
     8101 tcctcaccgg aaaacaactt cgggcgaaac aggcggtaaa gctggggttg gtggatgacg
     8161 tcgttccgca ctccatattg ctggaagccg ctgttgagct ggcaaagcag gatcgcccat
     8221 cttcacgccc tctacctgtt cgcgagcgta ttctggcggg gccgttaggt cgtgcgctgc
     8281 tgttcaaaat ggtcggcaag aaaacagaac acaaaacgca aggtaactat ccggcgacag
     8341 aacgcatcct ggaggttgtc gaaacgggat tagcgcaggg gaccagcagt ggctatgacg
     8401 ccgaagctcg ggcgtttggt gaactggcga tgacgccgca atcgcaggcg ctgcgcaata
     8461 tcttttttgc cagtacggac gtgaaaaaag atcccggcag tgatgcgccg cctgcgccat
     8521 taaacagcgt ggggattcta ggtggtggct tgatgggcgg cggtattgct tatgtcactg
     8581 cttgtaaagc ggggcttccg gtcagaatta aagatatcaa cccgcagggc ataaatcatg
     8641 cgctgaagtt cagttgggat cagcttgagg gcaaagttcg ccgtcgtcat ctcaaagcca
     8701 gcgaacgtga caaacagctg gcattaatct ccggaacgac ggactattgc ggctttgccc
     8761 atcgcgatct gattattgaa gcggtgtttg aaaatctcga attaaaacaa cagatggtgg
     8821 cggaagtgga gcaaaattgc gctactcata ccatctttgc ttcgaacacg tcatctttac
     8881 cgattggcga tatcgccgct cacgccacgc gacctgagca agttattggc ctgcatttct
     8941 tcagtccggt ggaaaaaatg ccgctggtgg agattattcc tcatgcgagt acatcggcgc
     9001 aaaccatcgc caccacggta aaactggcga aaaaacaggg caaaatgcca attgtcgtgc
     9061 gtgacaaagc tgggttttac gtcaatcgca tcttagcgcc ttacatcaat gaagctatcc
     9121 gcatgttgac cgaaggcgag cgtattgagc atatcgatgc cgcgctagtg aaatttggtt
     9181 ttccggtagg cccaatccaa cttttggatg aggtaggaat cgacacaggg actaaaatta
     9241 tgcctgtact ggaagccgct tatggagaac gttttagcgc gtctgcaaat gttgtttctt
     9301 caattttgaa cgacgatcgc aaaggcagaa aaaatggtcg gggtttctat ctttatggtc
     9361 agaaagggcg taaaagcaaa aaacaggtcg atcccgccat ttacccgctc attggcgtac
     9421 aagggcaggg gcgactctcc gcaccgcagg ttgctgaacg gtgtgtgatg ttgatgctga
     9481 atgaagcagt acgttgtctg gacgagcagg ttatccgtag cgtgcgtgac ggggatattg
     9541 gtgcggtatt tggcattggt tttccgccat ttctcggtgg accgttccgc tatatcgatt
     9601 ctctcggcgc aggcgaagtg gttgcaataa tgcaacgact ggccacgcag tatggttccc
     9661 gttttacccc ttgcgatcgt ttagttgaga tgagcgagcg tggggaaagt ttttggaaaa
     9721 caactgcaac tgacctgcaa taagaaggtc aaagttatat gaatccgcgc tgaatggcgg
     9781 agtgttgctc aaaatgtaaa cgcatattga ctatacttac gccattgagg taaaaaacag
     9841 cgtttcattc ggtgaatgga taaggcacaa tgccggccac cgttttcttt ctctggtttc
     9901 agatgaaaga aaacgggcga atctggttaa caaaagcggt gcaatatgca agtttttatc
     9961 atgcgtcacg gcgacgcagc cctcgatgcc gccagtgatt cggttcgtcc tctgaccact
    10021 catggttgtg acgaatctcg cctgatggcg aactggctga aaggtcaaaa agtggaaatc
    10081 gaacgcgttc tggtgagccc gttcctgcga gccgagcaaa cacttgaaga agtaggggat
    10141 tgtctgaacc tgccttccag tgcagaagtt ctgccggagt taacgccctg cggcgatgtt
    10201 ggtctggtcg gtgcctattt gcaggcgttg accaatgaag gtgttgcttc ggtactggtg
    10261 atctcccact taccgttagt tgggtatctg gttgccgagt tatgtccggg cgaaacgccg
    10321 cctatgttta ccacgtcagc gattgccagc gtaacgcttg atgaaagcgg aaaaggccaa
    10381 ttcaactggc agatgagccc ttgtaatttg aagatggcaa aagcaattta agcaatcaat
    10441 gcccggttac gtgc
//
LOCUS       DAFGPF010000158        10315 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFGPF010000158 DAFGPF010000000
VERSION     DAFGPF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.158"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..309
                     /locus_tag="LSX49_004619"
     CDS             <1..309
                     /locus_tag="LSX49_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1A family transposase"
                     /protein_id="HBL7170916.1"
                     /translation="LRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESR
                     LKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ
                     "
     gene            418..780
                     /locus_tag="LSX49_004620"
     CDS             418..780
                     /locus_tag="LSX49_004620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL7170917.1"
                     /translation="MRMVELASQPGACVAQIARENGVNDNVIFKWLRLWQNEGRISRR
                     IPVTTTSDAGVELLPVEITPDEPKEPMAALTPSLSTQTTVSASSCKVEFRHGNMTLEN
                     PSPELLTVLIRELTGRGR"
     gene            777..1127
                     /gene="tnpB"
                     /locus_tag="LSX49_004621"
     CDS             777..1127
                     /gene="tnpB"
                     /locus_tag="LSX49_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL7170918.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLF
                     IFRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPVVRDGKVSITRSQLAMLLDKLDW
                     RQPKTSRLNALTML"
     gene            1158..1379
                     /locus_tag="LSX49_004622"
     CDS             1158..1379
                     /locus_tag="LSX49_004622"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170919.1"
                     /translation="MSQKYLIRIAELESQLRQKDQQLSLVEETEAFLRSALARAEEKI
                     EEDEREIEYLRAQARCRKNPGWAKRSAMY"
     gene            1331..1672
                     /locus_tag="LSX49_004623"
                     /pseudo
     CDS             1331..1672
                     /locus_tag="LSX49_004623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014839879.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1736..2215)
                     /locus_tag="LSX49_004624"
     CDS             complement(1736..2215)
                     /locus_tag="LSX49_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003863366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBL7170920.1"
                     /translation="MMDYEDFSPKEQLQLTVCQRLIAEKSYFSQEELRRDLQERGFET
                     ISQSTVSRLLNLLGVIKIRNAKGLKVYSLNPQLRPAPDAARTVSEMVVSVEHNREFIL
                     IHTVAGYGRAVARVLDYHQLPEILGVVAGSSIVWVAPRMVKRVALVHKQINYLLRTY"
     gene            complement(2296..3699)
                     /locus_tag="LSX49_004625"
     CDS             complement(2296..3699)
                     /locus_tag="LSX49_004625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBL7170921.1"
                     /translation="MGKFKFPSAYTILFFLIAIVAVLTWIIPAGQYHMAMNEALGKEV
                     PVAGTYAHVEANPQGLISVLMAPIAGLYDPDSGQARAIDVALFILIIGGFLGIVTKTG
                     AIDAGIERVTTRLRGREEWMIPILMALFAAGGTIYGMAEESLPFYTLLVPVMLAARFD
                     PVVAASTVLLGAGIGTLGSTINPFATVIAANAAGIPFTNGITLRVVVLVIGWIICVTW
                     VMRYARKVRKEPSLSIIADKQEENLAHFLGNKSEQALEFTPVRKIILVIFALTFAVMI
                     YGVAVLGWWMAEISTVFLASAIIIGLIARMSEEELTSTFINGARDLLGVALIIGIARG
                     IVVIMDKGMITHTILHYAEGMVTGLSTVAFINVMYWLEVVLSFLVPSSSGLAVLTMPI
                     MAPLADFANVNRDLVVTAYQSASGIVNLITPTSAVVMGGLAIAHVPYVRYLKWVAPLL
                     GILTVVIMVALSLGALL"
     gene            complement(3747..4751)
                     /gene="argF"
                     /locus_tag="LSX49_004626"
     CDS             complement(3747..4751)
                     /gene="argF"
                     /locus_tag="LSX49_004626"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL7170922.1"
                     /translation="MTINLKKRNFLKLLDYTPAEIQYLIDLAIKLKAAKKAGREKQTL
                     VGKNIALIFEKTSTRTRCAFEVAAFDQGAQVTYLGPGGSQIGHKESMKDTARVLGRMY
                     DGIEYRGYGQAIVEELGKYAGVPVWNGLTDEFHPTQILADLMTMLEHSPGKKLSELSF
                     AYLGDARNNMGNSLMVGAAKMGMDIRLVAPKSFWPDVVLVEQCRSIAEETGARITLTD
                     DVEEGVWGTDFLYTDVWVSMGEPKEAWTERVSLMKPYQINADVMNATGNPNVKFMHCL
                     PAFHNEHTKVGREIEMAYGLKGLEVTEEVFESPNSIVFDEAENRMHTIKAVMVATLGD
                     "
     gene            complement(4836..5747)
                     /gene="arcC"
                     /locus_tag="LSX49_004627"
     CDS             complement(4836..5747)
                     /gene="arcC"
                     /locus_tag="LSX49_004627"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006810310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL7170923.1"
                     /translation="MERKPTLVVALGGNALLKRGEPLEAEIQRQNIELAARTIAGLTV
                     NWRVVLVHGNGPQIGLLALQNSAYDKVTPYPLDVLGAESQGMIGYMLQQALKNSLPQR
                     EVSVLLTQVEVDATDPAFSNPTKYIGPVYNEDQAKTLAAEKGWGFKADGSYFRRVVPS
                     PQPKRIVESDAITALIQRDHLVICNGGGGVPVVEKANGYRGIEAVIDKDLSAALLAYQ
                     IGADALLILTDADAVYLDWGKPTQRPLAQVTPELLRGMQFDTGSMGPKVAACCKFVEA
                     CNGIAGIGALVDGAEILAGNKGTLIRN"
     gene            complement(5758..6978)
                     /gene="arcA"
                     /locus_tag="LSX49_004628"
     CDS             complement(5758..6978)
                     /gene="arcA"
                     /locus_tag="LSX49_004628"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBL7170924.1"
                     /translation="MEKHYVGSEIGQLRSVMLHRPNLSLKRLTPSNCQELLFDDVLSV
                     ERAGEEHDIFANTLRDQGVEVLLLTDLLTQTLDIKEAKTWLLETQISDYRLGPTFAGD
                     VRSWLADMPHRELARRLSGGLTYGEIPAAINNMVVDTHTSNDFIMKPLPNHLFTRDTS
                     CWIYNGVSINPMAKPARQRETNNLRAIYRWHPAFADGDFIKYFGDENIYYDHATLEGG
                     DVLVIGRGAVLIGMSERTTPQGVEFLANSLFKHRQAERVIAVELPKHRSCMHLDTVMT
                     HIDVDTFSVYPEVVRKDAQCWTLTSNGRDGLQRTQETDLLHAIEKALGIDQVRLITTG
                     GDAFEAEREQWNDANNVLTIRPGVVIGYERNVWTNEKYDKAGITVLPIPGDELGRGRG
                     GARCMSCPLERDGI"
     gene            7871..8353
                     /locus_tag="LSX49_004629"
                     /pseudo
     CDS             7871..8353
                     /locus_tag="LSX49_004629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001609301.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
     gene            complement(8299..8745)
                     /locus_tag="LSX49_004630"
                     /pseudo
     CDS             complement(8299..8745)
                     /locus_tag="LSX49_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="RepA; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
     gene            complement(8738..8812)
                     /gene="tap"
                     /locus_tag="LSX49_004631"
     CDS             complement(8738..8812)
                     /gene="tap"
                     /locus_tag="LSX49_004631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HBL7170925.1"
                     /translation="MPGKVQDFFLCSLLLRIVSVGWCD"
     gene            complement(9048..9305)
                     /gene="repA"
                     /locus_tag="LSX49_004632"
     CDS             complement(9048..9305)
                     /gene="repA"
                     /locus_tag="LSX49_004632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HBL7170926.1"
                     /translation="MSQTENAVTSSSGKKRPYRRGNPVPARERQKASLARRSATHKAF
                     HAVIQLRLKEKLSELADEDGITQAQMLEWLIESEVKRRKSL"
     gene            complement(9589..9795)
                     /locus_tag="LSX49_004633"
     CDS             complement(9589..9795)
                     /locus_tag="LSX49_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HBL7170927.1"
                     /translation="MKYLNTTDCSLFLAGRSKFMTKYALIGLLAVCATVLCFSLIFRE
                     RLCELNIHRGNTVVQVTLAYEARK"
     gene            complement(9982..10164)
                     /locus_tag="LSX49_004634"
     CDS             complement(9982..10164)
                     /locus_tag="LSX49_004634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170928.1"
                     /translation="MMARKFGKQLIVAVSEKDAIKLKDNFDIIGMLSYGKENFIAMSH
                     TKSELTGGKRRYRIKN"
     gene            10265..>10315
                     /locus_tag="LSX49_004635"
     CDS             10265..>10315
                     /locus_tag="LSX49_004635"
                     /inference="COORDINATES: protein motif:HMM:NF015750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170929.1"
                     /translation="MASVSISCPSCSATDGV"
BASE COUNT         2547 a         2618 c         2603 g         2547 t
ORIGIN      
        1 ctccggaaga cggttgttgc gcatgtattc ggtgaacgca ctatggcgac gctggggcgt
       61 cttatgagcc tgctgtcacc ctttgacgtg gtgatatgga tgacggatgg ctggccgctg
      121 tatgaatccc gcctgaaggg aaagctgcac gtaatcagca agcgatatac gcagcgaatt
      181 gagcggcata acctgaatct gaggcagcac ctggcacggc tgggacggaa gtcgctgtcg
      241 ttttcaaaat cggtggagct gcatgacaaa gtcatcgggc attatctgaa cataaaacac
      301 tatcaataag ttggagtcat tacccttaga cgcccatctg acacagacgg acatctaagt
      361 atggaattac aggactgacg aaaagaacct cgtaaaaagt attcgaatga attcaaaatt
      421 cgtatggttg aactggcatc acaacccggt gcttgtgtgg cccagattgc acgagaaaat
      481 ggcgtcaatg ataatgttat tttcaaatgg ctcagactct ggcaaaacga agggcgtata
      541 tcacggcgta ttccggtgac aaccacttct gacgcaggcg ttgaattatt acctgtagag
      601 ataacgcctg atgagccgaa agaaccgatg gctgctctta ctccgtcctt atccactcag
      661 actactgtca gtgccagctc ctgcaaggtg gagttccgtc acggtaacat gacgctggaa
      721 aatccttcac cagagctgct cactgtattg attcgtgaac tgaccgggag gggaagatga
      781 tctcactccc atcaggtacc cgtatctggc tcgttgccgg cgttaccgat atgcgtaaat
      841 ccttcaacgg actgggagaa caggtacaac atgtgctgaa tgataatccc ttctccggtc
      901 acctgtttat cttccgtggc cgacggggtg acaccgttaa aattctttgg gctgatgctg
      961 atggtctgtg cctgttcacc aaacgcctgg aggaaggcca gtttatctgg cctgtggtac
     1021 gtgacggcaa ggtatccatt acccgctcgc aactggcaat gctcctcgat aagctggact
     1081 ggcgtcagcc aaaaacatcc cgccttaacg ccctgacaat gttgtaaaaa acgcctggcc
     1141 gcattataaa aacggccatg agtcagaaat acctcattcg cattgcagaa ctggaaagcc
     1201 agctccgtca gaaagaccag caactgagtc tggttgaaga gacggaggcc ttcctgcgct
     1261 ctgcactggc acgtgccgaa gaaaagatcg aagaagatga acgggaaata gaatatctgc
     1321 gggctcaggc acgctgtcga aaaaatccag gctgggcgaa gcgttcagct atgtactgaa
     1381 tcagtgggac gccctctgtt attacagtga tgacggtctg gcggaggcgg acaataacac
     1441 agcggaaaga gcgcttcgtg cattctgtct cggaaagaaa aattacgtgt tcttcggtag
     1501 cgatcacggc ggcgagtgtg gtgcactgct gtacgggctg atcggcacct gccgtctgaa
     1561 cggtatcgat ccggaagcgt atctgcgcca tattctgagc gtactgccgg aatggccctc
     1621 caaccgtgtt gacgaactcc tgccatggaa cgtagttctc accaataaat aagcgtcaat
     1681 acggtgctcc gttgacgctt acgtattagt caatacaagc gggcatttgt gaatattaat
     1741 acgttcttag taaataatta atttgcttat gcaccagagc gacacgcttc accatccgag
     1801 gagcgaccca gacgatactg cttccggcca ccacgcctaa aatttctggt aactggtgat
     1861 aatcaaggac acgtgccact gcgcggccat atccagcaac ggtatggata aggataaatt
     1921 ctctattgtg ctcaacgctc accaccattt cggacacagt gcgcgcggca tcaggagccg
     1981 gacgcaactg tggattcagc gaatagactt ttagcccttt ggcatttcga atttttatga
     2041 cacctaacaa attgagcaga cgagaaacgg tggactggct gattgtctca aaaccacgct
     2101 cctgtaagtc gcggcgaagc tcctcttggg aaaaatagct cttttctgca atcagacgtt
     2161 ggcagaccgt tagctgtagt tgctctttgg gagagaaatc ttcgtaatcc atcataatcc
     2221 tatattcagt tctcgaaata accggtgaca ccacaccatt ccgtagaccg gataggggca
     2281 gcgccatccg gcaaattaca acaatgcccc cagacttaat gccaccataa ttaccactgt
     2341 taatatccca agcagcggcg caacccattt cagatatcgc acgtaaggca cgtgggcgat
     2401 agccagtccg cccatcacaa cggcagaggt gggagtgatc aggttaacga taccggacgc
     2461 agactggtaa gccgtaacta ccaggtcgcg gttgacgtta gcgaagtcgg caagaggtgc
     2521 catgatcggc atcgtcagaa cggccagacc ggacgaagaa ggcacaagaa acgacagcac
     2581 cacttccagc caatacatca cgttgatgaa tgctactgtc gataatccag taaccattcc
     2641 ctcggcgtag tgcaaaatag tatgggtaat cataccttta tccatgatca ctacgatacc
     2701 gcgcgcgata ccgataatca gtgcaacgcc cagcaaatct cgcgcgccgt tgataaaggt
     2761 agaggtcagt tcctcttcgc tcatgcgggc gatcagaccg atgataattg cgctggccag
     2821 aaataccgtt gagatctccg ccatccacca acccagcacc gccacgccgt agatcatgac
     2881 cgcgaaggta agggcgaaaa tcaccagaat aattttgcgt accggggtga actccagagc
     2941 ctgttcgctt ttattgccga ggaagtgggc gaggttctcc tcttgtttat ccgcaataat
     3001 ggagagagac ggctccttgc gaactttccg ggcatagcgc atcacccatg tcacgcagat
     3061 tatccagccg atgacaagca ccaccacacg caaggtgata ccgttggtga aggggatccc
     3121 ggctgcattg gcggcgatca ccgtcgcgaa agggttaatg gtggagccga gcgtgccgat
     3181 cccggcgccg agcagcacgg tggaggcggc taccacaggg tcgaagcgtg ctgccaacat
     3241 caccggcacc agcagggtat aaaacggcag ggattcttcg gccatgccgt aaattgtacc
     3301 gccagcagca aacagcgcca taaggatcgg gatcatccac tcttcgcgac cacgtagtcg
     3361 ggtggtgacg cgctcgattc cggcgtcaat ggccccggtt ttggtgacga tcccgaggaa
     3421 tcctccgatg atcagaataa acagcgcaac gtctatcgcc ctagcctgac cggagtctgg
     3481 atcatacaac ccggcaattg gggccatcag cactgaaatc agtccctgcg gattggcctc
     3541 tacgtgtgca taggtgccgg caacaggaac ctccttgccg agagcttcgt tcattgccat
     3601 gtgatactgc ccggctggaa tgatccacgt caggacggca acgatggcaa tcagaaaaaa
     3661 gagaatggta tatgcggagg gaaatttgaa cttacccatg atgttctcct gagacccggt
     3721 gccccctacg acgcaccggg tggtgattag tcgccgagtg tcgccaccat gaccgcttta
     3781 atggtatgca tgcggttttc tgcttcatca aagacgatag agttagggga ttcgaagacc
     3841 tcttccgtca cctccagtcc cttcaggccg tatgccatct caatttctcg gcccactttg
     3901 gtgtgctcat tgtggaaggc tggcaggcag tgcatgaact tgacgttcgg gttgccggtg
     3961 gcgttcatca cgtcagcgtt gatttgataa ggcttcatca ggctgacgcg ttcggtccac
     4021 gcctctttcg gttcacccat tgagacccaa acatcggtgt agaggaaatc cgttccccac
     4081 acgccttctt ccacgtcatc ggtcagggtg atacgtgcgc ccgtctcttc cgcgatggaa
     4141 cggcactgtt caacaagcac cacatccggc cagaaggatt ttggggctac aagacggata
     4201 tccatcccca ttttggcagc ccccaccatc agggagttac ccatgttgtt gcgtgcgtcg
     4261 ccaaggtagg caaagctcag ttccgacagt tttttgcccg gggaatgttc cagcatggtc
     4321 atcaaatctg cgaggatttg ggttgggtga aattcgtcgg tcagaccgtt ccacaccggt
     4381 acgcccgcgt atttgcccaa ctcctcaacg atggcctgac cgtaaccacg gtattcgatg
     4441 ccgtcataca tacggcccag cacacgggcg gtgtctttca ttgactcttt atggccgatt
     4501 tgcgatccgc ctgggccgag gtaggtcacc tgcgcccctt ggtcgaacgc agccacttcg
     4561 aaagcacagc gggtacgggt ggaggttttt tcaaaaatca gggcaatgtt tttgccaacc
     4621 aaggtctgtt tttctcgtcc ggcttttttg gccgctttca gtttgatcgc gagatcgatc
     4681 aggtactgga tctctgccgg ggtgtagtcc agcagtttaa ggaagttgcg ttttttcaaa
     4741 ttgatggtca ttaggaaatc ctttttaaat tttaactgtc tgatgccctc actctgccat
     4801 ctcccctttg aggagagggt taggtgaagg gggattcagt tacgaatcaa tgtgccttta
     4861 ttgcccgcca aaatctcagc cccgtcgacc agagcgccga tcccggcaat accgttgcaa
     4921 gcttcaacaa acttgcagca ggcggccact ttcggcccca tcgatccggt gtcaaactgc
     4981 atgcctctga gcagttctgg cgtcacctgc gctagcggac gctgggtcgg tttgccccaa
     5041 tcgaggtaaa ccgcgtcggc atcagtgaga atcagtagtg cgtcggcccc tatctggtat
     5101 gccagcaggg cagcagagag gtctttgtcg atcaccgcct caattccgcg atagccgtta
     5161 gccttttcca caactggtac accaccgccg ccgttgcaga taacaagatg gtcgcgctgg
     5221 atcagtgccg taatagcatc gctctcgaca atgcgtttcg gctgtggaga tggcaccacg
     5281 cgacggaagt agctgccgtc ggccttaaac ccccaacctt tttctgctgc cagtgttttt
     5341 gcctggtctt cgttgtacac cggtccgata tatttggtcg ggttgctgaa cgccgggtca
     5401 gtagcgtcca cttccacctg agtaagcagg acgctcacct cacgctgtgg caggctgttt
     5461 ttcagcgcct gctggagcat gtagccgatc atcccctggc tttcggcgcc aagaacgtcc
     5521 agtggataag gggtcacttt gtcgtaggcg ctgttctgca gcgccagcag cccgatctgt
     5581 ggaccgttgc cgtgaaccaa caccacgcgc caattcaccg tgagcccggc gatggtacgg
     5641 gcggccaact caatgttctg gcgctggatt tctgcttcca gtggttcgcc gcgcttcaat
     5701 aatgcgttgc cgcccaacgc cacaaccaaa gtgggttttc gttccatgat ggctccttta
     5761 aattccgtcg cgttcaagcg gacagctcat gcagcgtgcg ccgccgcggc ctcgtcccaa
     5821 ttcgtccccc gggatgggca gcacggtgat gccggctttg tcgtatttct cgttagtcca
     5881 gacgttgcgc tcgtaaccaa tcaccacacc ggggcggatg gtcagaacgt tattggcgtc
     5941 gttccactgc tcacgttcgg cttcaaaggc gtcgccgccg gtggtgatca agcgtacctg
     6001 gtcaataccg agtgctttct cgatggcgtg caacaggtcg gtttcctggg tccgttgtag
     6061 gccatcgcgt ccgttcgaag tgagcgtcca gcactgggcg tctttgcgca ccacttccgg
     6121 gtaaacggag aaagtgtcaa cgtcgatgtg ggtcatgacg gtgtcaaggt gcatacagga
     6181 gcggtgtttt ggcagctcaa cggcgatcac tcgctcggcc tgacgatgtt tgaacaggct
     6241 gttggcgagg aactccacgc cctgcggtgt tgtgcgttca gacatgccga tcaataccgc
     6301 cccacgacca atcactaata cgtcgccacc ttccaaagtg gcgtggtcgt aataaatatt
     6361 ttcgtcgccg aaatacttaa taaaatcgcc gtcggcaaat gccgggtgcc agcgatatat
     6421 tgcccggagg ttattggttt cacgttgacg ggctggtttg gccatcgggt taatagaaac
     6481 accgttataa atccagcagg aggtatcgcg ggtaaataaa tgattcggta gcggcttcat
     6541 aataaagtca ttagacgtgt gggtatccac caccatattg ttaatggcag ccggaatttc
     6601 accgtaagtt aatccgccgc ttaatcttcg cgccagttca cggtgcggca tgtccgccag
     6661 ccagctgcgc acatcgcccg caaaggtagg tccgaggcgg tagtcagaaa tttgcgtctc
     6721 cagtaaccaa gttttcgctt ctttaatatc aagggtttgt gtcaggaggt ctgttaacag
     6781 caggacttcc accccctgat cgcgcagcgt atttgcgaag atgtcatgct cttcacctgc
     6841 ccgttcaacc gagagtacat catcgaaaag cagttcctga caattcgatg gtgtcaaacg
     6901 tttcagactt aaatttgggc ggtgcagcat aacactacgc aattgaccaa tttcagaacc
     6961 gacgtaatgt ttttccataa ttattccttt aattttttta gaataaaaag gtatgcgcca
     7021 tgttgtgtat ttaatttcat ggcggctaac ttcaattgat ttcgtggttc atactaggcg
     7081 gtaaaataaa cattattgtg atgagattca cacaataatg gatattaagg tatttgtttt
     7141 aatttgtgtt acttgcatta aataatgatt aatttcataa tgtcagctca tgaatagata
     7201 gtcattattt gggtggaaat atctctattt gttattattt tgtggagttt gctgttttaa
     7261 ggtgattata tatttatatg attttaaaag taaaaaaact gtagcgtgaa taattatgaa
     7321 ataattgcaa tttaactttt tttggcttaa taaaaggctg taaatagtta tgaaatcata
     7381 aagaaaaatt attaatgtga taaaatgtga tatgttctca ggttttgtga ttttatttta
     7441 taattctggt ggttgtgttg gcgttatcac acgctcgaaa tgaagttatg cataaccgct
     7501 gcataattac ctgtgtatga ttaacaatga tttaacaccc ttcccgataa acatgagctc
     7561 gcttagatgt cacaggaaaa gggctagtat ggcagcactg gttttcgtat gaaagaaaga
     7621 taaaacattg ccttatatct aaggcttctt gattatcggt aacatccacc atctccagcc
     7681 atagctggca ggtggtgacg ttggtgcagt actggcggga gcttcggctc cggaactggc
     7741 atacctgctg aaatcaacag aaaaagaccc ggcagtaaag gccattgctc acgccattct
     7801 gggcggtgca gtagcagcaa tgcagagtaa taatgttgct gctggtgcag caggcgcagc
     7861 aacaggagag ctggcagcca gagcgatcgg aatgctgtat ccgggagtga agctgtctga
     7921 cctcagtgaa gagcagaagc agacgataag tacgctggca accgtgtcag cagggctgac
     7981 cggcggtcta accggaaaca gcaccgcatc agctgcagtg ggagcacaca gagcgggaag
     8041 aatgctgttg agaataacta cctgagcgtg tctgaaaaga cagaacttga gatagcaaaa
     8101 cagacgatta aaaacagtaa agatccggca gagcgtgaaa aggcacagca gaaatatgat
     8161 gcattgcttg aaaaagatat tcagtgataa ggaggttatt gctgcctgta gtaatggtaa
     8221 tgcgggtagt tcagcgtgtg ccagcgcaag actgaaagct attgcgtcga aagaagggta
     8281 cgaagatggc ccttataacg agatatcggt cggaatgttg cagccaataa gcgggtcata
     8341 ttccgtctgg tagctaatca gccccagctc tgacaggaac gtcagggcac gggtggcacg
     8401 ggtgatggag agtgttccgg cagcagactc cgtcgccagc ccgcactcaa tggccagcgt
     8461 ggtgatggag cactggacac ggttggccag cgggtcatag tggaaacaca gcccctgcag
     8521 cagcgcatca atagcccgtc gacgcagcac cggtggcatg cgccgacgca gtcccttcga
     8581 acgggcatgc gccacatgaa tagcgcaatc aaaacgggag gtgaagccca ccgccttttc
     8641 catcagtttt tcgcagaact tcagcgttcc tgcaccttca cggggtgtaa acaccggatt
     8701 cgggttcttt acctggcggt aatacgtttg ttgaagatca gtcacaccat cctacgctta
     8761 caatgcgcag aaggagtgag cacagaaaga agtcttgaac ttttccgggc atataactat
     8821 actccccgca tagctgaatt gttggctata cggtttaagt gggccccggt aatcttctct
     8881 tagtcgccaa acctggtgaa gattatcggg gtttttgctt ttctggctcc tgtaaatcca
     8941 catcagaacc agttccctgc caccttacgg cgtggccagc cacaaaattc cttaaaacga
     9001 tcagcaatct aacatctcat cactgaaaca gcaagaaacg caaatactca caaagatttt
     9061 ctgcgcttaa cctctgactc tatcagccac tcaagcatct gtgcctgagt gatcccgtct
     9121 tcatcagcaa gctcacttaa cttttctttc agtcgaagct gaatgacggc atgaaacgct
     9181 ttatgagtgg cactccttct tgcaagagac gctttttgtc gttctctcgc aggaacagga
     9241 ttaccccttc tgtaaggtcg tttttttccc gatgaggaag tcactgcatt ttctgtctgc
     9301 gacatctcgc ctcctcaata atcaaacaga gatcgtttcg cagaggatac tacagttttt
     9361 tgaaatcagc gacttgaaag ttgtgacgat gatcggtgtt ggcgcacaaa tcatgtctga
     9421 ttacaaccgt ttaatgtgat tttgataatg aaatgactga aaagcaggaa atgccttaac
     9481 caggatgccg gccccgggcg ggaccggctg tttctggcat gtcgggtgtc tgcccctgaa
     9541 atacctcaca cttccggaaa gcggggactt ccgtccccgc ccggcagctt acttccgtgc
     9601 ttcgtaggcc agagttacct gcaccactgt atttcccctg tgaatattca gttcacataa
     9661 ccgttccctg aatatcagtg aaaaacacaa caccgtggcg cacacggcga gcaacccgat
     9721 aagggcatat ttcgtcataa actttgacct ccctgcaagg aagaggctac aatcagtagt
     9781 gttaaggtac ttcatgcaga cctcacgagt taatggatta acgagtgggg tcttcgcatt
     9841 tctggtacct gcgtcttgcc tgaaccagaa aggctcagac acccgccgcg ataataccac
     9901 attccctgtt gctgactatt accttcattt cccgcttttt actaccgaaa ctccagccaa
     9961 taagtatgct ttttatttat atcaattttt aatccggtac cgacgtttcc ctccagttaa
    10021 ctcgcttttc gtatgactca tggcaataaa attttcttta ccatatgaca acatcccaat
    10081 aatatcaaaa ttgtctttta atttgatggc atccttttca cttacagcga caataagttg
    10141 tttaccaaat tttctggcca tcattgcaaa ctgtgatact gctgatccac cacctaaatc
    10201 aggccacccg gtgatgctgc caacttactg atttagtgta tgatggtgtt tttgaggtgc
    10261 tccagtggct tctgtttcta tcagctgtcc ctcctgttca gctactgacg gggtg
//
LOCUS       DAFGPF010000159        10227 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFGPF010000159 DAFGPF010000000
VERSION     DAFGPF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10227
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.159"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            179..600
                     /gene="tnpA"
                     /locus_tag="LSX49_004636"
                     /pseudo
     CDS             179..600
                     /gene="tnpA"
                     /locus_tag="LSX49_004636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525033.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            878..1798
                     /gene="iolE"
                     /locus_tag="LSX49_004637"
     CDS             878..1798
                     /gene="iolE"
                     /locus_tag="LSX49_004637"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463285.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HBL7170930.1"
                     /translation="MGASNMYNVKKSIKLGIAPIGWRNDDIPEIGKENTYKQILSDAA
                     LTGFSGTEVGGCYPQDPAELNKELMLRGLEIPGQWFSSFIIRDGIASAMNAFEQHCAY
                     LQAIHAYVAVVSEQTYSIQGIIDKCVYTEKPNFSDSEWQLLCEGLNALGKIANAHGLK
                     LAFHHHMGTGVQTLPEVDRLMENTDPQFVHLLFDTGHIYVSDGDVMPLLSKHFDRIKH
                     VHFKDVRNEKLKACRLAKKSFLNSFLDGVFTVPGDGNIDFKSVLAYLVGHQYSGWIVV
                     EAEQDPKKYNPLEYAQKGKKHIDELLKNYL"
     gene            1817..2827
                     /gene="iolG1"
                     /locus_tag="LSX49_004638"
     CDS             1817..2827
                     /gene="iolG1"
                     /locus_tag="LSX49_004638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase IolG1"
                     /protein_id="HBL7170931.1"
                     /translation="MTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAA
                     LDKYAIEAKDYNDYHDLINDKDVEVVIITASNEAHADVAVAALNANKYVFCEKPLAVT
                     AADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGRHYNAST
                     VPEYKTPQAIYETLIHEIDIMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTS
                     GINIVVEVFVNCQYGYDIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFI
                     DAYDIEFQDFFDRLNAGLPPAGPTSWDGYLAAVTADACVKSQETGNTEIVELPSKPDF
                     YK"
     gene            2925..4268
                     /gene="srfJ"
                     /locus_tag="LSX49_004639"
     CDS             2925..4268
                     /gene="srfJ"
                     /locus_tag="LSX49_004639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysosomal glucosyl ceramidase-like type III
                     secretion effector SrfJ"
                     /protein_id="HBL7170932.1"
                     /translation="MKGRLISSDPYRQQFLVERAVSFSHRQRDCSELISVLPRHTLQQ
                     IDGFGGSFTEGAGVVFNSMSEKTKAQFLSLYFSDQEHNYTLARMPIQSCDFSLGNYAY
                     VDSSADLQQGRLSFSRDEAHLIPLISGALRLNPHMKLMASPWSPPAFMKTNNDMNGGG
                     KLRRECYADWADIIINYLLEYRRHGINVQALSVQNEPVAVKTWDSCLYSVEEETAFAV
                     QYLRPRLARQGMDEMEIYIWDHDKDGLVDWAERAFADEANYKGINGLAFHWYTGDHFS
                     QIQYLAQCLPDKKLLFSEGCVPMESDAGSQIRHWHTYLHDMIGNFKSGCSGFIDWNLL
                     LNSEGGPNHQGNLCEAPIQYDAQNDVLRRNHSWYGIGHFCRYVRPGARVMLSSSYDNL
                     LEEVGFVNPDGERVLVVYNRDVQERRCRVLDGDKEIALTLPPSGASTLLWRQESI"
     gene            4269..5102
                     /gene="iolI1"
                     /locus_tag="LSX49_004640"
     CDS             4269..5102
                     /gene="iolI1"
                     /locus_tag="LSX49_004640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-myo-inositol isomerase IolI1"
                     /protein_id="HBL7170933.1"
                     /translation="MMKLGFNEATCMRNSTLAQDVVLAERFGYDYIEIRLDMLQEWLQ
                     KHTLSELADIFAVGHLKPWGYNSLEDITFCDSESWAEKRRQLAFACHAGSVVGGDCLV
                     VVPTIRQGGNFPPGETVKDSVKRLREMAAVAEESQMRLAFEPIGSAGCCVRSLAMAME
                     IVDAVDRSNVGLVVDAFNLYLHDQWRDLTTLRQIPVEKIFVYHIDDADNLPLATLEHC
                     HRLFPGNGVIPLHEITHELVQKGYEGICSLELFNPGYWQMAASEVFAIGAEKTRPFLA
                     A"
     gene            complement(5099..6265)
                     /locus_tag="LSX49_004641"
     CDS             complement(5099..6265)
                     /locus_tag="LSX49_004641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170934.1"
                     /translation="MPALTQHSTSITLFRISAAMFLNYLTIGIPLVMLPLYVQQQLHL
                     SDLLIGIAVGSQFIATLLTRGAAGRKADTSGGRRTVITGQFYCAASGLLMLVSLIAHP
                     VPLLAWAILIVGRVLLGIGESFILTGNLTWGMWLAGSTHAGQVISWNGMATYGALAIG
                     APLGLSLYARAGLALPALLVVLLPIIARGVIYGIPGNIPTARPRVPVLRVVGLVWRPG
                     TGLVLQGIGFATLSAFTALWFNERHWDNTGFAMTLFGIAFIAVRFFCAKFPDRYGGAT
                     VATFSLLVEGTGLAVMWSAPSAGAALIGAAITGCGCSLMFPSLGVEVVRRVPPEIRGT
                     ALGVWSAFQDLAYGFTGPIAGLLTPFIGYQQVFLLAAACALLGAAVVHLLLRQH"
     gene            complement(6468..7655)
                     /locus_tag="LSX49_004642"
                     /pseudo
     CDS             complement(6468..7655)
                     /locus_tag="LSX49_004642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013747467.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
     gene            complement(7659..8006)
                     /locus_tag="LSX49_004643"
     CDS             complement(7659..8006)
                     /locus_tag="LSX49_004643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL7170935.1"
                     /translation="MARSAKPRKQKSSRQSTRSAPLLRWRVIPCSGGTDNEAGLFFPD
                     FASAADYCMEKDIPCLFEEDASGNYETTVWIVGEPDGNVTMLPMSWKNFLSVCTIHPF
                     ICPLCGTSHLPPA"
     gene            complement(8142..10079)
                     /gene="iolC"
                     /locus_tag="LSX49_004644"
     CDS             complement(8142..10079)
                     /gene="iolC"
                     /locus_tag="LSX49_004644"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HBL7170936.1"
                     /translation="MSMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKY
                     LGGSSGNVAYGTAIQGLRSAMLARVGDEHMGRFVREELNRVGVDTQCLLSDRDRLTAL
                     VILGIKDQDTFPLIFYRDNCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVL
                     KALEYAQKHGLRRVLDIDYRPVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVG
                     TEEEFHIAGGSTDTLTALRRVRQLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGV
                     RVDVLNVLGAGDAFMSGLLRGYLNDESWEQACRYANACGALVVSRHGCAPAMPTKKEL
                     DDYLAREQSITRPDKDPRLNHLHRVTTRKQHWPELCVFAFDHRKQLVDIANEVGASES
                     AIPPLKMLLLEGARQAALEAGLQNNSGILADTTFGQQALNDVTGQGWWIGRPVEMPGS
                     YPLKLEHGDIGSQLVSWPQEHVVKCLVFYHPLDAESVRLEQEALIDEVYRACCQSGHD
                     LLLEVILPRDTADQNEQYYPQIVERFYQLGILPDWWKLPPLSPDRWREISQHIEHYDP
                     ECRGILILGLDAPESELKSGFAAAADMPWVKGFAVGRTIFGEPSRQWLGGQLNDEQLI
                     ATVKQKYRMLIDYWREYRPAR"
BASE COUNT         2509 a         2573 c         2718 g         2427 t
ORIGIN      
        1 atgcttgcta aaatttaatc gtcatgagaa tggtcgcaat actgcggcca ttttttattg
       61 ttattcctaa accacctcct agggaggtgg tgattgatcc tgtaaggcta tagcctgaag
      121 aatgcccatg tcggaatatc tctgcttact caccacaagt aaaaggagac aaactgacat
      181 ggggctttat agaagtttat cacatgtata ttggcgttgc aaatatcaca tagtctggac
      241 gccaaagtac cgctttagga tcctgaggga taaattgggc aaggagctgt acagaaccat
      301 ctatatactt tgcggaataa aagattgcta aatgtacagc cagatcatgt gcatcttgtc
      361 gtaatagtgc cgccaaaaat ctcaatatct actctgatgg ggcacctgaa aggtcgcagt
      421 gcaatcaggc tctacaatcg attcccgcat atcaggaaga agttatgggg aaaccatttt
      481 tggtcgcggg gttactttgt cgatacggta ggcgtgaacg aagaaattat cagacgatat
      541 gtgaggcatc aggaaaagat ggaacaaaca catgaacagc agatggagtt gctagagtag
      601 aaaacggaat atgacattcg ccccccttat agggggcatt ctgaaaagcc acctcctcat
      661 gaggtggtct tttacttgtc ggtatatttt attcgtttat ctatagcgcg aaaagtctgg
      721 caatatcatt aaagagtgat gatttttttg tgatacctga cgcatttatc ccacttcttc
      781 aaccaggata gataaagttt ttcaggctac aaaaagtaat atgttgtcca tcaaaggtta
      841 attcgcatcg cggtatgcag taaaagcgtt tcattaagtg ggagccagca acatgtacaa
      901 tgtaaaaaag agcattaagt tggggattgc gcctatcggt tggcgcaatg atgatattcc
      961 tgagattggt aaagaaaata catataaaca aatacttagt gatgccgcgc tcaccggttt
     1021 ttccgggacg gaagttggcg gttgttatcc gcaggatcct gctgagttaa ataaagagtt
     1081 aatgcttcgc ggcctggaaa taccaggcca gtggttttct tcctttatta ttcgcgatgg
     1141 tattgcatct gcgatgaatg cttttgaaca gcattgtgct tatttgcagg caatacatgc
     1201 atatgtcgcc gttgtttctg aacaaactta tagtattcaa ggtattatcg ataagtgcgt
     1261 ttatacagag aagcctaact tcagcgacag tgaatggcag cttttatgcg aaggacttaa
     1321 tgcgcttggg aagattgcca atgcgcacgg gctgaagctc gctttccatc atcatatggg
     1381 taccggtgtg cagactctgc cggaagtgga tcgactcatg gagaataccg atccgcaatt
     1441 tgtacatctg ctgtttgata ccgggcatat atatgtttct gacggcgatg tcatgccgct
     1501 actgagtaaa cattttgatc gtattaaaca cgttcatttt aaagatgtgc gtaatgaaaa
     1561 actcaaagca tgtcgcctcg cgaagaaatc attcctcaat tctttccttg atggtgtgtt
     1621 taccgtcccc ggcgatggaa atattgattt taaatccgta ttagcttatc tggtcgggca
     1681 tcaatattct ggctggattg ttgttgaggc cgagcaggat cctaagaaat ataacccatt
     1741 ggaatatgcg caaaaaggta aaaagcatat tgatgagtta ctgaaaaatt atctttaatt
     1801 gaaaaggaaa cagaaaatga ctttaaaagc aggtattgta ggtatcggca tgatcggctc
     1861 cgatcactta agacgtctgg ccaacaccgt gtcgggtgta gaggttgttg ccgtatgtga
     1921 tatcgtcgcg ggtagggcgc aggcggcgct ggataagtat gcgatcgaag ccaaagatta
     1981 taatgactat cacgatctga ttaatgataa agacgttgaa gtggtcatca ttaccgcatc
     2041 aaatgaggcg cacgccgatg tggccgttgc cgcgctaaat gctaacaaat atgttttctg
     2101 cgaaaaaccg ttagcggtga cggctgcgga ttgtcagcgt gtgattgaag cagagcagaa
     2161 aaatggtaag cgcatggtgc agattggttt tatgcgccgc tacgacaaag gttacgttca
     2221 gctgaaaaat attatcgaca gcggcgaaat cggtcagcca ttaatggttc atggacgtca
     2281 ttacaatgcc agcacggtgc cagaatacaa aacgccacag gctatctatg aaacattgat
     2341 tcatgaaatt gacattatgc actggctgct taacgaagat tataaaaccg ttaaggttta
     2401 cttcccgcgt cagtccagcc tggtgaccac tctgcgtgat ccgcagctgg ttgtaatgga
     2461 aaccacctcc ggcatcaata ttgtggttga agtatttgtg aactgccagt atggctacga
     2521 cattcactgc gatgttaccg gcgagaaagg aatggcggag ctgccaaccg tcgccagcgc
     2581 tgcggtacgg aaagcggcga agtatagcac cgacatcctg gttgactgga aacagcgctt
     2641 tattgatgcc tacgacattg agttccagga tttcttcgat cgcctgaacg caggattgcc
     2701 gccagcaggc ccaacgtcat gggatggtta tctggctgcg gttaccgctg atgcctgcgt
     2761 gaagtctcag gaaacaggga ataccgagat tgttgaatta ccctcaaaac ctgatttcta
     2821 caaataaacc ttccgcgtat taaaaccttc tgccggatag cgatgcttaa gcgtcctatc
     2881 cggcatatca caatttatta tcttctttta tccggaactt ccctatgaaa ggcagactca
     2941 tctcttccga tccgtatcgt cagcaattcc ttgttgagcg tgcggtctct ttttcgcatc
     3001 gtcagcgtga ttgcagtgaa ttaatcagcg tcttaccgcg ccacacgtta cagcagattg
     3061 acggattcgg cggcagcttt accgaaggtg cgggcgtggt attcaacagc atgagcgaaa
     3121 agacgaaggc gcaatttctt tccctttatt tttctgatca ggaacataat tacactctgg
     3181 cgcggatgcc aattcagagc tgtgattttt ccctgggcaa ttacgcgtat gtcgattcca
     3241 gcgctgacct gcagcaggga cggctctcct tttcccgcga tgaagcgcat ttaataccgc
     3301 tgatttccgg ggcgttgcgg ttaaatccac acatgaagct gatggcttcg ccgtggagtc
     3361 cgccggcgtt tatgaaaact aataacgata tgaacggtgg cggcaagctg cggcgcgaat
     3421 gctacgccga ctgggccgat atcattatca actacctgct ggaataccgc cgccacggca
     3481 ttaatgtgca ggcgctctcc gtgcagaatg agccggtggc ggtaaaaacc tgggactcct
     3541 gtctgtatag cgtggaagag gagacagcct ttgccgtgca gtatctgcgt ccgcgcctcg
     3601 cccggcaggg tatggatgag atggagatct atatctggga tcacgataaa gatggcctgg
     3661 tagactgggc tgaacgcgcc tttgctgacg aagctaatta taagggaatt aacgggctgg
     3721 cattccactg gtataccggc gaccattttt cgcaaataca gtatctggcc cagtgcctgc
     3781 cggataaaaa actcctgttt tccgaaggct gtgtgccaat ggagagcgat gccggtagcc
     3841 agattcgcca ctggcatacc tatctccatg acatgattgg taatttcaaa tcgggttgta
     3901 gcgggtttat cgactggaat ctgctgttga acagtgaggg tgggccgaat catcagggta
     3961 atctgtgtga agcgcccatt caatacgatg cgcaaaacga cgtgctgcgg cgtaaccact
     4021 cctggtatgg tattggccac ttctgccgct atgtgcgtcc gggggcgagg gtcatgcttt
     4081 cttcaagtta cgataatctt ctggaagagg tgggatttgt gaatcccgac ggcgagcgtg
     4141 tgctggtggt gtataaccgc gatgtccagg aaaggcgttg ccgggtgctg gatggcgata
     4201 aagagatcgc gttaacgctg ccgccgtcag gcgccagtac gttgctatgg cggcaggagt
     4261 cgatctgaat gatgaagctg ggatttaatg aagcgacctg tatgcgaaac tccacgctgg
     4321 cacaggatgt tgtgttggcg gaacgttttg gctatgacta cattgaaatc cgtctggata
     4381 tgttgcagga gtggttgcag aaacatacgt taagcgagct ggcagacatt ttcgccgtcg
     4441 gccatcttaa gccctggggc tacaattcgc tggaagacat tacgttttgt gatagcgaaa
     4501 gctgggcgga gaaacggcgg cagttggctt tcgcctgcca tgctggctca gtggtggggg
     4561 gggattgtct ggttgtggtg cccaccattc gtcagggggg aaattttccg ccaggggaaa
     4621 cggtgaaaga ttcagtgaag cgtctgcgcg agatggcggc agtggcggaa gaaagccaga
     4681 tgcggctggc ctttgagccg atcggttccg caggatgctg tgtgcgcagt cttgccatgg
     4741 cgatggagat cgtagatgcg gtcgatcgca gtaacgtcgg gctggtcgtc gatgccttta
     4801 atctttacct gcacgatcaa tggcgggatc tgaccacgct tcgccagatc cctgtggaaa
     4861 agatcttcgt ttaccatatt gatgacgccg ataatctgcc gctggcaacg ctggagcatt
     4921 gccatcgtct gtttcctggc aacggcgtga tcccactgca tgagatcacg catgagctag
     4981 tgcagaaggg ctatgagggg atctgttcgc tggaactgtt taaccctggc tactggcaga
     5041 tggcggccag cgaagtcttt gcgatagggg cggaaaagac tcgccccttc ttagcagctt
     5101 aatgttgccg cagcaggaga tggacaaccg ccgcgcccag cagcgcgcag gccgcggcca
     5161 gaagaaagac ctgctgatag ccgataaacg gcgtcagcag gcccgctatt ggtccggtaa
     5221 atccgtaggc cagatcctga aacgctgacc agacgccgag ggccgtacca cgaatctccg
     5281 gtggcactct gcgcacaacc tctacgccca gcgatgggaa catcagcgaa cagccgcagc
     5341 cggtaatcgc cgcgccaatc agcgcagcgc ctgctgacgg agcggaccac attaccgcca
     5401 gtccggtccc ctctaccagt agtgaaaagg ttgcgaccgt ggcgccgccg taacggtcgg
     5461 gaaatttggc gcagaaaaag cggacagcga taaacgcaat gccaaatagc gtcatcgcaa
     5521 aaccggtgtt atcccagtga cgctcgttga accagagggc ggtaaacgcg cttagggtgg
     5581 caaaaccaat gccctggagc acaagccctg ttccgggccg ccacaccagg ccgactaccc
     5641 gtagcactgg cacgcgggga cgggctgttg ggatattccc cggaatgcca tagatgactc
     5701 ctctggcgat gatcggcaac agcacgacga ggagcgccgg aagcgccagg ccggccctgg
     5761 cgtaaagcga cagccccagc ggcgcgccga tagccagcgc accgtaggtc gccatgccgt
     5821 tccaggaaat aacctgaccc gcgtgggtcg agcccgccag ccacatcccc caggttaaat
     5881 taccggtcaa aatgaaactt tcaccgatgc ccagcagcac acgaccaaca atcagtatgg
     5941 cccatgcgag cagcggaacc gggtgagcga ttagactgac cagcatcagc agacctgatg
     6001 cggcgcagta gaactgaccg gtgataaccg tccgacgtcc gcctgacgtg tcggcttttc
     6061 gacccgcggc gccccgggta agcaaggtgg cgataaactg gctgcctacc gcgataccga
     6121 tcaacagatc gctcagatgc aactgctgct gaacgtacag cggcagcatg actaacggga
     6181 tgccaatagt cagatagttg agaaacatcg cggcgctgat gcgaaacagc gtgatcgatg
     6241 tggaatgttg tgtgagagct ggcatggaat cgtccttgat cgataggaat taaaatcccc
     6301 aaaagactaa aaaaaacacc acaaaacgga tattacttct acatcctttg cgcaccatat
     6361 aaacgaaaat gacgattaaa caggatgact ctgattgata cagagtataa atggcgattt
     6421 tttgctccgt tccccaaaaa atggacacaa cttcacctct gcggctctca gccgcacacc
     6481 cgctgtcgtg ccagtggctc atgcatcatg accagctctg ccagtcggta gccacgcttc
     6541 aggcccgtaa aacgcatctg actcccgcac agaatgcact tcagcgggtc aaccttcagt
     6601 aaccgctgat acatccctct ccacctgatt tgcatcgccg tttttcgcac cgtctccgtt
     6661 atggcataca caacctcttc cagtaacggg cgcttcaccg gactcaggaa cccgtagtac
     6721 ctcaccatcc ggaatccctt atccgccaca tgccaggaga acctttccat gaactcatca
     6781 ccgctcatca caaggtattc ttaccgtttt gtccggtgac tgttgtaacg caggccagtt
     6841 tcatcctgac ctgcataatg ctccagacga ctcatcggaa ccggcggctt tttgaggtaa
     6901 gagccagagt acaccgccac gtgggtggcg ttatccatta ccctggagac gttgacattc
     6961 cagccccggc agtgatgtgt gtccaggagg cgattccagt cccgtttgct gtttccttcc
     7021 gcggtcagct catccggtat caccaggtca gggtattttc gtgacagtaa ccgagttatc
     7081 cggtaacgcc acatactcat caccttacgg gcgtaaaaat gaagattttt ccaggtgtga
     7141 cctgatgtca caccaccggc agttgtcgat aaatggatat gcggatgcca ctgctggtct
     7201 cgtccccagg tgtggattac cgtgaatatt cccggctaca catctgcctg gcggcagatt
     7261 tccagtatca catccgctgc gatatggctc atctctgcca gtaaccaccg gttgtggaac
     7321 accagggacc agtactggca cggaagcgtg aacacaatat gctgccacgg gcagtcgggg
     7381 accagactca gcagatactg tatccactgt gcgcctgctt ttactccgca gtgcggacag
     7441 gaacggcttt tacaccggaa gcagaccttc tttgtgtggc aacagtccgg tgacgaacag
     7501 caccattgcg tgtaccccat cagcgtggtc ccacaggcca tgatttttgt cactgactca
     7561 atcaccaccg gacgcacgga accttccggc tgtttctcca gccagttaag ccagcggtta
     7621 ccatgctgaa aaatgtcggc aaaacgggga agcatgaatt acgcaggggg aagatgtgag
     7681 gtgccgcaca gcggacagat aaagggatgt atcgtgcaca cggacagaaa atttttccat
     7741 gacatgggga gcatggtgac attaccgtcg ggctcaccga ctatccatac ggttgtttca
     7801 taattgccgc tggcatcttc ttcaaacagg cacggaatat ctttctccat acagtaatcg
     7861 gcagcgctgg cgaagtcggg aaaaaacagc ccggcttcat tatctgttcc tccggagcag
     7921 gggatcaccc gccatcgcaa caggggagct gagcgggtgg attgtctgct ggatttttgt
     7981 ttgcgaggtt tagctgaacg ggccatataa ctacctgaaa gacaatgata ttgtctgttt
     8041 ttataacggt aatatcaggt catgacaagc cgcagccgcc aggctgccta ctcgaacacg
     8101 ccccttgtcc gatgcagaca cggggcgtga tgaggcaggc attaacgtgc cgggcggtat
     8161 tcgcgccagt agtcaataag catgcggtat ttttgtttca ccgttgcgat gagctgttca
     8221 tcgttaagct ggccgcctaa ccactggcgt gacggttcgc caaagatggt ccggccgacg
     8281 gcgaaacctt tcacccaggg catatccgct gctgcggcga atcctgactt caactcgctt
     8341 tccggtgcgt ccaggccaag tatcaatata ccgcgacatt cagggtcata atgctcaata
     8401 tgctggctga tttctcgcca acgatctggg cttaacggcg gcagtttcca ccagtccggc
     8461 aggatcccca gttgataaaa acgttccaca atctgaggat agtattgctc attttggtct
     8521 gccgtatcgc gcggcaagat gacttccagc agcagatcgt gaccagactg gcagcaggcg
     8581 cggtaaacct cgtcaatgag cgcctcttgt tcaagacgta ccgactctgc atcgagtgga
     8641 tgatagaaga ccagacattt cacgacgtgc tcttgcggcc agctgacaag ctgagagcca
     8701 atatcgccat gttccagctt cagcggatac gaaccgggca tctcaaccgg tcggccaatc
     8761 caccatccct ggccggtcac gtcgttaagc gcctgctgac caaaggtggt atcggcaagg
     8821 atgccgctat tattctgtaa accggcctca agcgccgcct gacgcgcccc ttccagcagt
     8881 agcatcttca gaggggggat cgcggattca ctggcgccga cttcatttgc gatatccacc
     8941 agttgcttgc gatggtcgaa ggcgaatacg cacagctccg gccagtgctg tttacgggtt
     9001 gtgacccgat gaaggtgatt cagccgcggg tctttgtctg gccgggtgat ggattgttca
     9061 cgcgcgaggt agtcgtccag ctcttttttg gttggcatgg cgggggcaca accgtggcgc
     9121 gataccacta acgcgccgca ggcgtttgca taacggcagg cttgctccca gctttcatcg
     9181 ttcaggtatc cccgcagcag tcctgacata aaggcatcgc ccgcgcccag aacgttcaga
     9241 acgtctacgc gaacgccgct atgtatcttc acctgcgacc agtcatcggc aatgttgcct
     9301 tcaaagactg agcagcccag cgcgccgcgt ttgcacacca gtacggcttg ggtcaactga
     9361 cggacgcgcc gcagggcggt cagcgtgtcg gtactgccgc cggcgatatg gaattcttct
     9421 tcggtcccaa cgatcagatc gaaatggcgc aatacctgct ggagctgttc ggtaacctgt
     9481 gatgaggcga tgaaacgcgt ttcaccgtct cctagcgacg tcaggcccca cagtacgggg
     9541 cggtagtcga tatccagcac ccgccgcagc ccgtgttttt gcgcatactc cagtgcttta
     9601 agaacggcgg cgcgcgtatt ggggtgagaa agatgggtac cagtgacggc taatgcgcgt
     9661 gaagaagcga tgtaatcttc gcggatatcc tcgggtgtta gcgccatgtc cgcgcagtta
     9721 tcgcggtaga agatcagagg aaaggtgtcc tgatctttaa tgccgaggat caccagcgcg
     9781 gtcagacgat cgcgatccga cagcaggcac tgcgtatcca caccaacgcg gtttaattct
     9841 tcacgaacga aacgtcccat atgctcatcg ccgacgcggg ccagcatagc ggaacgtaat
     9901 ccctgaatgg ccgtgccgta ggcaacattg cctgacgatc cccctaaata tttagcgaaa
     9961 gtcgtcatat cctccagccg cgacccgatt tgttgaccat acaaatcaac agcgactcgt
    10021 cccagacaga taacgtccag cggcttttgc tcactactga ctgctttatt cattgacata
    10081 tcccctaaca gaagacggtg ttatttttgc ttatactaag gtttggtgat ttcattttca
    10141 ataaaaatgg aatgacgttt tcatttattg tttgaataag atcacagaaa tggcatttcc
    10201 gggcaacggg catgatcgtt ttttgtt
//
LOCUS       DAFGPF010000160        10180 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFGPF010000160 DAFGPF010000000
VERSION     DAFGPF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10180
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.160"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1626)
                     /locus_tag="LSX49_004645"
     CDS             complement(<1..1626)
                     /locus_tag="LSX49_004645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL7170937.1"
                     /translation="MWNLLRRTRKNQKSGRDVREAGWTSLFQAVAEPFSGAWQQGVKA
                     DPEAVLSFHAVFACISLISQDIAKMRLRLMQTDAHGIRRETRRGDIARLCRRPNAQQN
                     RIQFFELWLNAKLRHGNTVVLKIRNARGQIKELRILDWSRVEPLVADDGEVFYRITPD
                     RNCGITEAVTVPAREVIHDRFNCFFHPLIGLPPVYAAGLAATQGHHIQENSTSFFRNG
                     GRPSGVIEIPGSITEENAKKLKSNWDSGYTGENAGKTAILSNGAKYNPTTFSPVDAQT
                     VEQLKMTAEIVCSVFRVPAYKIGVGQPPSSDNVEALEQQYYSQCLQTLIESIELLLDE
                     ALETGENESTEFDVTTLLRMDSERRMKTLGDAVKNTLLTPNEARKRENLPPLAGGDAL
                     YLQQQNYSLEALSRRDAREDPFASAGKTVSSQLPDGASDGNKAISETEHDAVKAMFRG
                     DTEKMTERELSIIRALGEEFSTVLADLQRTFEGKMASQAQAFEEKLTSLSAVLQKHVT
                     VDEVRPVLQAMVDDAVGAIPVPRDGRDYDPDVLQ"
     gene            complement(1572..1793)
                     /locus_tag="LSX49_004646"
     CDS             complement(1572..1793)
                     /locus_tag="LSX49_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170938.1"
                     /translation="MAKIRYLQGTHDARAGDIRDVAQPCAEVLVRLGKAEYITVRRPA
                     GQKKKRDAEHGECGTFYGEPEKTRNQDVT"
     gene            complement(1838..3775)
                     /locus_tag="LSX49_004647"
     CDS             complement(1838..3775)
                     /locus_tag="LSX49_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL7170939.1"
                     /translation="MTLKRACSLLTVKSFSEDERVITGIASTPSPDRDGDILEPEGAE
                     FGSAIPFLWQHDHSRPVGQCTVRRVSEGLEITATLVKPVPDMPSQLAARLDEVWAAIK
                     TGLVRGLSVGFRPHEYTFLDGGGLHFLRWELMEVSAVTVPANAECTIRTIKSYDRPFS
                     AASGNRKPVVKIASSAGAAAQSTTVFHKEKTIMNIGEQIKSFENKRAALAASLEEVMT
                     KAAEEGRTLDVEEEEHYDNTAAEIRQVDAHLKRLRELEAGKAATAQPVKQAGNGNVAA
                     VASAPVIRVEQKLDKGIGFARFAKSLAAAKGVRSEALEVARRQYPDDSRLHHVLKSAV
                     GAGTTTDPQWAGSLSEYQEYAQDFIDYLRPQTIIGRFGQGGIPALRQVPFNIRVHAQV
                     SGGAAGWVGEGKAKPLTKFDFESITFSHAKVSAIAVLTEELIRFSSPAADALVRNALA
                     EAVVARLDTDFVDPKKAAVADVSPASITHDVKGTASTGNPDADAEAAFGQFVAANLQP
                     TGAVWLMSSTNALALSMRKNALGQKEYPDMTLLGGSFQGLPVIVSQYVGDQLVLVNAP
                     DIYLADDGGVAVDMSREASLEMQSEPTGDSTTPSPVELVSMFQTGSVAIRAERWINWR
                     RRRTAAVAVITGVNYGSASGG"
     gene            complement(3839..5500)
                     /locus_tag="LSX49_004648"
     CDS             complement(3839..5500)
                     /locus_tag="LSX49_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL7170940.1"
                     /translation="MIPVWSTACPDWAERLKKGLSIIPDPIYPDEAAHALAIFKQLRI
                     VDAPGSPTFGESCAPWVFDLVAALFGSYDAQTGVRHIKEVFILIPKKNSKSTLAAGIM
                     MTALLLNWRQAAGYTILAPTVEVAANAFNPARDMVRRDDDLDDLCQVQTHIRTITHRV
                     TDTTLKVVAADPNTVSGIKSVGTLIDELWLFGKQCKAEDMLREAIGGLASRPEGFVVY
                     TTTQSNEPPAGVFRQKLQYARDVRDGKIHDPHFLPVIFEHPPEMVESGTNLLMENLAM
                     VNPNLGYSVDEAFLYREYRKAREAGEETFRGFMSKHANVEIGLALRSDRWAGADFWEE
                     QGRCISLDDILRRADVVTVGIDGGGLDDLLGMYVIGRDRETREWLGWGHAWAHETAVV
                     RRKSEASRFQDLVACGDMTIVRRVGDDTAEVAEYVRRIHEAELLDHIGIDPSGVGQIL
                     DSLAEAGIPDGIVVGISQGWKLGGAIKTTERKLAEGVLVHGDQPLMAWCVGNARVEPK
                     GNAILITKQASGRGKIDPLMALFNAVSLMSLNPEPKKKEYAVFFI"
     gene            complement(5497..6060)
                     /locus_tag="LSX49_004649"
     CDS             complement(5497..6060)
                     /locus_tag="LSX49_004649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBL7170941.1"
                     /translation="MLTTQKRKFALALMSGKNKTASAIAAGYSAKTARVKGSQLAKDP
                     EVLAFIARKQCETVEVDEVPVYRQKKSEQEDKPRRREAAAIPQPDENNLEMPPSAVMS
                     PGIEYMEDGLPDPVKAMGRILVENLCIDPKLALDAAWRLAQFTHHKKGDTGKKSAKGD
                     AAKKAANRFAVPPPPRLVVNNDNEGNG"
     gene            complement(6351..6716)
                     /locus_tag="LSX49_004650"
     CDS             complement(6351..6716)
                     /locus_tag="LSX49_004650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL7170942.1"
                     /translation="MAELRTLQSRIKTLNTRRVNILKGEQRRVSGSARVSLKRHIWLR
                     DAGQCCICGRVVDLCDSELDHRIALQFGGGNEETNLWTLCAECHRQKSAREAASGMPD
                     PTLPEVSGGSGREDDIIGL"
     gene            6758..6958
                     /locus_tag="LSX49_004651"
     CDS             6758..6958
                     /locus_tag="LSX49_004651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HBL7170943.1"
                     /translation="MSSKNRTRRTTTRNIRFPNHIIEQINIALEHKGSGNFSAWVIEA
                     CRRRLATDATHLRPASMTNNEK"
     gene            complement(7157..7372)
                     /locus_tag="LSX49_004652"
     CDS             complement(7157..7372)
                     /locus_tag="LSX49_004652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170944.1"
                     /translation="MKKLRVTVEPFQGTIPFRILQRGRVLVEGSFSGKCTQLHSRTFQ
                     VNATNEELTVECTMNAAKCRMVLQPVC"
     gene            complement(7369..7461)
                     /locus_tag="LSX49_004653"
     CDS             complement(7369..7461)
                     /locus_tag="LSX49_004653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001443905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HBL7170945.1"
                     /translation="MMTMQKQLEGAQEYIRTQCTKLAFYYPEDT"
     gene            complement(7458..7643)
                     /locus_tag="LSX49_004654"
     CDS             complement(7458..7643)
                     /locus_tag="LSX49_004654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rz1 family lipoprotein"
                     /protein_id="HBL7170946.1"
                     /translation="MRELKMKLCALMLPLVVSACGSTPPAPVPCVKPPAPPAWIMQPA
                     PDWQTPLNGIISSSENG"
     gene            complement(7865..7951)
                     /locus_tag="LSX49_004655"
     CDS             complement(7865..7951)
                     /locus_tag="LSX49_004655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170947.1"
                     /translation="MSAELIRAMAFAIRIVAIAVLVWAIRWW"
     gene            complement(8506..9039)
                     /locus_tag="LSX49_004656"
     CDS             complement(8506..9039)
                     /locus_tag="LSX49_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HBL7170948.1"
                     /translation="MNAKIRYGLSAAVLALIAAGAPAPDILDQFLDEKEGNHTTAYRD
                     GAGIWTICRGAILVDGKPVVPGMKLSKEKCDRVNAIERDKALAWVEKNIKVPLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYRRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VFRRDQESALACWGIDR"
     gene            9145..9417
                     /locus_tag="LSX49_004657"
     CDS             9145..9417
                     /locus_tag="LSX49_004657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170949.1"
                     /translation="MDNNTISLQELLDSISRLREDVNTLTVAFSYLAFSIPREQMQST
                     LASIQFESCNPKWSQEQQDSFRRLAVLLDEKYAGKITISADSSENP"
     gene            complement(9383..9727)
                     /locus_tag="LSX49_004658"
     CDS             complement(9383..9727)
                     /locus_tag="LSX49_004658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdfR family protein"
                     /protein_id="HBL7170950.1"
                     /translation="MTQNYELIVKGIRNFENKVTVTLALRDKKRFDGEIFDLDISLDR
                     VEGAALEFYEAAARRSIRQVFLDVAAGLCEGDEQSPEKRPVILEAQDVLITYRGKLPG
                     IITGSLKSPPKW"
     gene            complement(9732..9947)
                     /locus_tag="LSX49_004659"
     CDS             complement(9732..9947)
                     /locus_tag="LSX49_004659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HBL7170951.1"
                     /translation="MYQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGS
                     LLFGLLTYLTNLYFKIREDRRKAARGE"
BASE COUNT         2279 a         3135 c         2429 g         2337 t
ORIGIN      
        1 ctgcagtaca tccggatcat aatcacgacc atcacgcggt accggaatgg cccccacagc
       61 gtcatccacc atcgcctgca gaaccggacg cacctcatcc accgtcacat gcttctgtaa
      121 taccgccgac agggaagtca gtttctcttc aaacgcttgt gcctgcgagg ccatcttccc
      181 ctcaaatgtg cgctgtaaat ccgccagcac tgtggagaat tcttctccca gtgcacgaat
      241 aatggacagt tcccgttccg tcattttctc agtatccccc ctgaacatcg ctttcaccgc
      301 atcatgctct gtttcactga ttgccttatt accgtcagat gcgccgtcag gcagctgtga
      361 tgaaactgtt ttcccggcag acgcgaacgg atcctcacgg gcatcacgac gggacagcgc
      421 ctccagactg tagttctgct gctgaagata cagtgcatca ccgccggcca ggggcggcag
      481 gttctcccgt ttacgggcct cattgggcgt gagaagcgta tttttcaccg catcccccag
      541 cgttttcatg cgccgctcac tgtccattct cagcagcgtg gtgacatcaa attctgtact
      601 ctcgttttcc cccgtttcca gcgcctcatc cagtaacagt tcaatggact caatcagcgt
      661 ctgcaggcac tgggaataat actgctgctc cagcgcctcc acgttgtcac tggaaggcgg
      721 ttgtcccacg ccaatcttgt aggccgggac acggaacacc gaacagacaa tttcagcggt
      781 catcttcagt tgttccaccg tctgcgcatc cacaggtgaa aacgtcgtgg ggttgtattt
      841 tgccccgttg ctcagaatgg ccgttttccc cgcattttcg cctgtatacc cgctgtccca
      901 gttgctcttc agttttttcg cattttcttc cgtaatactg ccggggatct caatcacccc
      961 ggacggcctg ccgccatttc tgaaaaaaga cgtcgaattt tcctgaatat gatgcccctg
     1021 cgtggccgcc agcccggcgg catacaccgg cggcaatcct ataagcggat gaaaaaaaca
     1081 gttaaaccgg tcgtggatca cttcccgggc aggcaccgtc accgcctccg tgatcccgca
     1141 gttccggtcc ggcgtgatgc ggtagaacac ctcgccgtca tccgccacca gaggttcaac
     1201 ccggctccag tccagaatac gcagttcttt gatctgcccc cgggcattac ggattttcag
     1261 caccaccgta ttgccatgac gcagtttggc gttcagccac agttcaaaaa actggatgcg
     1321 gttctgctgg gcgttgggac gacgacagag gcgggcaata tccccccggc gcgtttccct
     1381 gcgtatccca tgcgcatccg tctgcataag acgcagccgc attttggcga tatcctggga
     1441 tatcagcgaa atacatgcaa acaccgcatg aaaggagagg acggcttcag gatcggcttt
     1501 cacgccctgc tgccaggcgc cggaaaaggg ctcagccacc gcctgaaaca ggctggtcca
     1561 gcccgcctct cttacgtcac gtcctgattt ctggtttttt cgggttcgcc gtaaaaggtt
     1621 ccacattcgc catgctccgc atcacgtttc tttttctgac ctgccggacg tcgcaccgtg
     1681 atgtactccg cctttcccag gcgaaccagc acctccgcac acggctgtgc cacatcacgg
     1741 atatccccgg cccgggcatc atgcgtgccc tgcagatatc ggatctttgc cataacctgt
     1801 tacgggaggc gcacgcctcc cgtcctcctt atcagactca gccgccggac gcactgccgt
     1861 agttcactcc ggtgatcacc gccaccgccg cagtacggcg acgacgccag ttgatccagc
     1921 gctccgcacg gatggccacg ctgcctgtct ggaacatgga aaccagctcc accggggacg
     1981 gcgtggtact gtcgccggtc ggctcagact gcatttccag tgatgcctcg cgggacatat
     2041 ccactgccac gccgccgtca tccgccagat aaatatccgg ggcattcacc agcaccagct
     2101 ggtcacccac gtactgggag acaatcaccg gcagcccctg gaaggagcca cccagcaggg
     2161 tcatgtccgg gtattccttc tgacccagcg catttttacg catggacagt gccagggcat
     2221 tggtgctgga catcagccag accgcaccgg tgggctgcag gtttgctgcc acaaactgtc
     2281 caaacgcagc ctctgcatcc gcatccgggt taccggttga tgccgtgccc ttcacatcat
     2341 gggtgatgga cgccggggag acatctgcca ctgcggcttt tttcgggtcc acaaagtctg
     2401 tatccagacg cgccaccacc gcttccgcca gcgcattacg gaccagtgca tcagcagccg
     2461 gactggaaaa acggatcaat tcttccgtca gtaccgcaat ggccgacacc ttcgcatgac
     2521 tgaaggtgat ggattcaaaa tcaaacttcg tcaggggttt tgccttaccc tcacccaccc
     2581 agccggcagc accgccggac acctgggcgt gcacacggat attgaatggc acctgacgaa
     2641 gtgcagggat cccgccctga ccaaatcgcc cgataatggt ctgcggacgc aggtaatcaa
     2701 taaagtcctg tgcgtattcc tgatattcag acaggctgcc tgcccactgc ggatccgtgg
     2761 tggtccccgc gcccactgcc gatttcagga catgatgcag acgactgtca tccggatact
     2821 gacgacgggc cacttccagg gcttcagatc ggacgccttt agccgcagcc agcgatttgg
     2881 caaagcgggc gaagccaatc cccttatcca gtttctgctc cacacggatc accggcgcag
     2941 aagccaccgc ggccacattc ccgttaccgg cctgtttcac cggctgcgcc gtggcggcct
     3001 taccggcttc cagttcacgc aggcgcttca ggtgcgcatc cacctgacgg atttccgctg
     3061 cggtgttgtc gtaatgctct tcctcctcca catccagcgt gcgcccttcc tctgcggctt
     3121 tggtcatgac ctcctcaagg gaggctgcca gcgctgcacg cttgttttca aaacttttaa
     3181 tctgttcgcc aatattcatt atggtctttt ccttatgaaa aacggttgtt gactgtgccg
     3241 cagcgccggc agaagatgcg attttcacca ccggtttccg gttgccggac gcggcagaaa
     3301 acgggcggtc gtaagattta atggtccgga tggtgcattc cgcattcgcg ggcacggtga
     3361 cggcagacac ctccatcagt tcccagcgca gaaaatgcag tccgcctccg tccagaaagg
     3421 tgtattcatg gggacggaag cccacggaca gccccctgac cagcccggtc ttaatggccg
     3481 cccagacctc atccagccgg gcagccagtt gcgacggcat atccggtacg ggcttcacca
     3541 gtgttgccgt gatttccagc ccttcgctga cccggcgcac cgtacactgc cccaccgggc
     3601 gggaatggtc atgctgccag agaaacggga tcgcactgcc aaactccgcg ccctccggct
     3661 ccaggatgtc accatcccga tccggagaag gcgttgacgc aatcccggtg atcacccgtt
     3721 catcctcact gaaggatttc accgtcagca gggaacaggc ccgtttaaga gtcacatcag
     3781 cctcctgaaa ataaaaaaac cgccggagcg gttcgtgatg gttacagtgt gaacagggtt
     3841 atatgaaaaa aaccgcatat tctttctttt tcggttccgg gttaagggac atcagggaga
     3901 ccgcattgaa cagcgccatc agcgggtcaa tttttccccg tccactggcc tgtttggtga
     3961 taagaatggc gttaccttta ggctccaccc gggcattgcc gacacaccag gccatcaggg
     4021 gctggtcacc atgcaccagc accccttcag ccagtttgcg ctcggtggtt ttaatggccc
     4081 cgcccagttt ccagccctgg cttatcccca ccacaattcc gtcggggatc ccggcttccg
     4141 ccagtgaatc cagaatctgc cccacccctg acgggtcaat accgatatgg tccagtaact
     4201 cagcctcatg aatgcgacgc acatattccg ccacttccgc cgtgtcatcc ccgacacgcc
     4261 ggacaatggt catatctcca caggcaacaa gatcctgaaa ccgggacgcc tcgctcttcc
     4321 gtcggaccac cgcggtttca tgcgcccagg catggcccca gcccagccat tcgcgggtct
     4381 cccggtcacg cccaatcaca tacatcccca gcagatcatc cagccctccg ccgtcaatcc
     4441 ccaccgtcac cacatcagca cgacgcagga tatcgtccag gctgatacaa cggccctgct
     4501 cttcccagaa atcagccccc gcccagcggt cagagcgcag ggcaagacca atttccacat
     4561 tggcgtgttt tgacatgaac ccccggaatg tctcttcacc ggcttcccgg gctttacggt
     4621 actcccggta cagaaaggcc tcatccactg aatagccgag attcggattg accatggcga
     4681 ggttttccat cagcaggtta gtcccgcttt ccaccatttc aggagggtgt tcaaatatca
     4741 ccggcagaaa gtgcggatca tgaattttgc cgtcgcgcac atcccgggcg tactgcagtt
     4801 tctgtctgaa caccccggcg ggcggttcat tcgactgggt ggtcgtatac accacaaacc
     4861 cttccgggcg ggaggcaagg ccgcctatgg cttcacgtaa catgtcctcc gccttgcact
     4921 gcttgccaaa cagccacaac tcatcaatca gcgtacccac ggacttgata ccggacaccg
     4981 tattcggatc ggctgccacc accttcaggg tggtgtccgt cactcggtgg gtgatggtcc
     5041 ggatatgggt ctgtacctgg cagaggtcat ccagatcatc gtcacgtcgt accatatccc
     5101 gggcagggtt gaaggcgttg gccgccacct ccacagtcgg ggccagaatc gtgtaacccg
     5161 ccgcctgccg ccagttcagt aacagtgcag tcatcatgat ccccgcggcc agcgtggact
     5221 tcgagttttt cttggggata aggataaaaa cttccttgat atggcgtaca ccggtctgcg
     5281 catcgtagga gccaaacagg gccgccacca ggtcaaacac ccacggtgca caggactccc
     5341 cgaacgtagg gctaccaggt gcatccacaa tccgcagttg tttaaaaatc gccagggcat
     5401 gtgcggcctc gtccggataa atcggatccg gaataatcga cagccccttt ttcaggcgct
     5461 ctgcccagtc cgggcaggct gtgctccata caggtatcat ccgttgccct cattatcgtt
     5521 attcaccacc agtcgggggg gcggtggcac cgcaaaacgg ttagccgctt ttttcgcggc
     5581 atcacctttt gccgattttt tcccggtatc ccctttttta tggtgcgtga actgcgccag
     5641 acgccaggcc gcatccagtg ccagtttcgg atcaatgcag aggttttcca ccaggatccg
     5701 ccccatggct ttcaccggat cgggaagacc atcctccata tattcaatac caggagacat
     5761 caccgcggac ggtggcatct ccagattgtt ttcgtccggc tgtggtattg cagccgcctc
     5821 acggcgacgg ggtttatcct cctgctctga ttttttctgc cggtaaacag gaacctcatc
     5881 cacctccacc gtctcgcatt gtttacgggc tataaacgca agcacctcag gatcttttgc
     5941 cagctgcgag cctttaaccc tggcggtctt cgccgaataa ccggcggcaa tggctgacgc
     6001 tgttttgttt ttcccggaca tgagcgccag cgcaaatttt cgtttttgcg ttgtcagcac
     6061 agcctcctcc cgggtccaga acgcactcag ccgggtatgg ttcagcccat ttttcccggc
     6121 gtctcatgcc gcaaatgtta actgctgcct ggttaacatt tgctgaaaaa gcctgttaac
     6181 attttttccg cacaacaaac tgaataataa agataaaaac cgcaaaaatg cccgggcagc
     6241 cagttaacat gttaactgcc ctgaaacggg aattttttct ctgcgtgaga gggggcgcgg
     6301 tgtccaaagc gatcgttttt tacgccggat gatacccccc ccgggttggg ttacagtccg
     6361 atgatgtcgt cctctctgcc actacctccg gacacctccg gcagcgtcgg gtccggcata
     6421 ccactcgccg cttcacgagc agacttttgt cgatggcatt cggcacagag cgtccaaaga
     6481 ttcgtctcct cattaccacc accgaactga agtgcaattc ggtgatcgag ttcactgtca
     6541 cagaggtcaa ccacacgacc acagatacag cactgcccgg cgtccctcag ccagatatga
     6601 cgcttgaggg aaacacgtgc actgccactg acacgacgct gctccccctt cagaatattc
     6661 acccgtcggg tattcagtgt tttgattctg ctctggagtg tacgaagctc agccatgtaa
     6721 aatccccgtc atatggcaat cagtaaagga aataaatatg tcatcgaaaa accggacccg
     6781 cagaaccaca acccgcaata tccgtttccc caatcacata attgaacaga tcaacatcgc
     6841 ccttgagcat aaagggtccg gtaacttttc agcgtgggtt attgaagcct gcaggagaag
     6901 gctggcaaca gatgcaacgc atctgcgccc ggccagcatg acaaataacg agaaatgaac
     6961 gttcggtttc ttccaccatc gcaccggaca ggcgactatg aggggacaac gccgcgctcc
     7021 gttaacgcgg taaaccccgg tgtgtatcgt ttttgattat ccccgcacac tcgcgcagag
     7081 gagtctccct gtcgggctgc ggtctctgtt aatgcaggaa tacggcgaca ataccgcgca
     7141 tggataataa ggtcgctcaa cacactggct gtaataccat gcggcattta gcggcattca
     7201 tcgtacactc cacggttagc tcttcattcg tggcattcac ctgaaaggtc cgggagtgta
     7261 attgcgtaca tttaccactg aacgaacctt caacaagaac acgaccacgc tgcaaaatac
     7321 ggaacggaat tgttccctga aaaggttcta cggttacccg taatttcttc atgtatcctc
     7381 cggataataa aaagccagct tagtgcactg agtgcggata tattcctgcg ccccttccag
     7441 ctgcttctgc attgtcatca accgttctct gaggatgaaa taatcccgtt cagcggtgtc
     7501 tgccagtcgg gggccggttg cattatccac gctggaggtg ccggtggctt cacgcacggt
     7561 accggggcag gtggcgttga cccgcaggcg cttacgacca gcggcaacat cagcgcgcag
     7621 agtttcattt tcagctctcg catcggctaa ttccttcgtg tatctggcat caagcgcagc
     7681 gacatctcgc tggcgctgct gcatgtcagt aatagtggca ttcgccagtt tcagctcact
     7741 gactttttta tcgcgctgcg ctttgtaggt gatggcgtta tcgcggtaat gattcagccc
     7801 cagactaagc acaccacagg ctaccagcat gacaataatc accacacaca gaacacggtt
     7861 catatcacca ccaacggatt gcccagacca gaacagcaat ggccacaata cgaatggcaa
     7921 atgccattgc ccgaataagt tcagcactca tctttttaaa gttcacgatt tcagcgcaat
     7981 gaccagtttt gccagcccat acagcatcgg agacacagca ataccaacag ccacccactt
     8041 aatagcaaaa gccagcgctc tgctgatgtc atcagtcact gtcaccccag cagccccgac
     8101 gaagacaaca tcacccaggc gagggacaga aaaagagcaa ccagcattag tgaaaatgaa
     8161 ataccgacaa tcacacacag gacctttgcc ggcgttatga gtttgtctga catagctacc
     8221 ccttaattgc cacaattaac tgggatacta cccataaaaa agggatgctc cagaccagca
     8281 aaaatttcca gtttggtaat tgactaatca tgagtcgcaa ctccctaatc agtttgctaa
     8341 aatcaatcaa ggcagcctcc catagcttac tgccataaaa acaaaacccc gcttgctgcc
     8401 aacaaacggg gtttttactt ttattcactt aggttttgcc agttcacagg acttcgtgtt
     8461 atccgcccgc gttggccaac ctcatttttc agcaaaatat tctgcttatc tgtcgattcc
     8521 ccagcacgcc agcgcgctct cctggtcacg acggaatacc tgaccgtaac agttatttga
     8581 gcgaatacgg cagtctctgc caccgtcctt aatccaccag cgaatcgctt cgcatgctcc
     8641 cctgcgatca cctgcattaa ttcgtctgta aaacgtcgac gggaaacact taccgggacc
     8701 aatgttgtac ggacagaatg acgcgatccc cgctttctgg ggttcggtca atggcacttt
     8761 gatgtttttc tccacccatg ccagcgcctt atcacgctca atggcgttaa cccggtcgca
     8821 tttttccttc gacaacttca tgcccggaac gacaggtttg ccatccacca ggatggcacc
     8881 gcggcagatg gtccagatac ccgcgccatc acggtatgcc gtggtgtggt taccttcctt
     8941 ttcatccaga aactggtcga gaatgtcagg cgcaggcgca ccagcggcaa tcagcgccag
     9001 aacggcagcc gacaggccgt atctgatttt tgcgttcatg gatatttatc aggatttatc
     9061 ggtttctgag ccctggatat gtttatcagt tccagcctgt tgcctcaggc tgctaacagg
     9121 tcaatacaat catgaggatt atttatggac aataacacca tttctctaca ggagttgctc
     9181 gacagcattt ccaggcttcg ggaagacgtg aataccctta ccgtcgcctt ctcatatctg
     9241 gcattctcaa ttccaaggga acagatgcaa tcaacgctgg catcaatcca gtttgaatca
     9301 tgcaatccca aatggtctca ggaacaacaa gactctttca ggcggcttgc tgtattactg
     9361 gatgaaaaat atgctggtaa aattaccatt tcggcggact cttcagagaa cccgtaatta
     9421 ttcccggtag ttttcctctg taggttatca acacatcctg cgcctctaaa attacggggc
     9481 gcttttccgg cgactgctca tccccttcac ataacccggc agcaacatcc aggaagacct
     9541 gtctgatgct ccttctggct gctgcctcat aaaactccag cgcggcacct tcaacacggt
     9601 ccagcgagat gtccaggtca aaaatttcac cgtcaaagcg ttttttgtcc cgtaacgcta
     9661 aagttaccgt aactttattc tcaaaattgc ggatcccttt cacaatcagt tcatagtttt
     9721 gagtcattga attactctcc ccgtgccgcc ttacgacggt cctctctgat tttgaaatac
     9781 aggttagtca gatatgtcag cagcccaaac agcagactcc ccagcacgcc tattgccgcc
     9841 cactgagacg gggaaaccct gtccagcaac tgcaggaacc agtagcccgt tcccaccgct
     9901 gacgtggtgt atgacacacc tgttgtgatt ttttccatct ggtacatacc ccgtctcccg
     9961 ttatccggaa gctgacaaca ataaaaaaag ccaccagtta agtactgatg gctctgataa
    10021 ctcatgcagg catctcagac gacccactga cactaccggt gagtttaacg ataccttcca
    10081 tttgactggc tcacttttta tgatgatgcc ggtgcattta tctccagcac cagactttct
    10141 atctcaacgc catacgttgc atttttggta atatccgtca
//
LOCUS       DAFGPF010000161        10000 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFGPF010000161 DAFGPF010000000
VERSION     DAFGPF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10000
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.161"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            56..736
                     /locus_tag="LSX49_004660"
     CDS             56..736
                     /locus_tag="LSX49_004660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBL7170952.1"
                     /translation="MSDNRSRHDRLAVRLSLIISRLMAGESLSLKTLSDEFGVTERTL
                     QRDFHQRLVHLDLEYRNGRYSLRRQSSPGAIPEMLSFIQNTGIARILPLRNGRLITCL
                     TDNQEPSPCLIWLPAPDITATFPECFSQLILAIRQCIHISLMTERWYPSLEPCRLIYY
                     SGSWYLIALQKGKLQVFPLADIKSVSLTSERFERRGHIHSLVAEERFISALPHFSFIH
                     KLINTFNL"
     gene            884..1561
                     /locus_tag="LSX49_004661"
     CDS             884..1561
                     /locus_tag="LSX49_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170953.1"
                     /translation="MNTRALFPLLFTVASFSASAGNWAVKNGWCQTMTEDGQALVMLK
                     NGTIGITGLMQGCPNGVQTLLGSRISINGNLIPTSQMCNQQTGFRAVEVEIGQAPEMV
                     KKAVHSIAERDVSVLQAFGVRMEFTRGDMLKVCPKFVTSLAGFSPKQTTTINKDSVLQ
                     AARQAYAREYDEETTETADFGSYEVKGNKVEFEVFNPEDRAYDKVTVTVGADGNATGA
                     SVEFIGK"
     gene            1567..1800
                     /locus_tag="LSX49_004662"
     CDS             1567..1800
                     /locus_tag="LSX49_004662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HBL7170954.1"
                     /translation="MSDCHPVLLPEGPFSREQAVAVTTAYRNVLIEDDQGTHFRLVIR
                     NAEGQLRWRCWNFEPDAGKQLNSYLASEGILRQ"
     gene            1890..2708
                     /locus_tag="LSX49_004663"
     CDS             1890..2708
                     /locus_tag="LSX49_004663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBL7170955.1"
                     /translation="MQLASRFGHVNQIRRERPLTREELMYHVPSIFGEDRHTSRSERY
                     AYIPTITVLENLQREGFQPFFACQTRVRDQSRREYTKHMLRLRRAGQITGQHVPEIIL
                     LNSHDGSSSYQMLPGYFRAICTNGLVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTTDILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSARGKRIHTRAIHSIDTDIKLNRALWVMAETLLESMR"
     gene            2800..3285
                     /locus_tag="LSX49_004664"
     CDS             2800..3285
                     /locus_tag="LSX49_004664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBL7170956.1"
                     /translation="MTTFSHSSTTPSVSVTTASGNNQSQLVATPVPDEQRISFWPQHF
                     GLIPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFIAPEPDEDDGETWILFNA
                     MNGNRAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECNAIMRII
                     D"
     gene            3300..3776
                     /locus_tag="LSX49_004665"
     CDS             3300..3776
                     /locus_tag="LSX49_004665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HBL7170957.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNKLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEHGLL"
     gene            3845..4066
                     /locus_tag="LSX49_004666"
     CDS             3845..4066
                     /locus_tag="LSX49_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBL7170958.1"
                     /translation="MKIITRGEAMRIHQQHPASRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            4145..4522
                     /gene="cbtA"
                     /locus_tag="LSX49_004667"
     CDS             4145..4522
                     /gene="cbtA"
                     /locus_tag="LSX49_004667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HBL7170959.1"
                     /translation="MSDTLPGTTHPDDNHDRPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTITLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPAAPAITV"
     gene            4569..4946
                     /locus_tag="LSX49_004668"
     CDS             4569..4946
                     /locus_tag="LSX49_004668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HBL7170960.1"
                     /translation="MNTLPDTHVREASGCPSPVTIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSAGAPSQLINSIDILRARRATG
                     LMTRNNYRMVNNITQGKHPEAKQ"
     gene            4943..5431
                     /locus_tag="LSX49_004669"
     CDS             4943..5431
                     /locus_tag="LSX49_004669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170961.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDVDGVNLSELINKVSENGYL
                     LRVVDKSDQHATSTPPPLTTLTCIRCSTAHITETDNAWLYSLSHQTNDDGESEWIHFT
                     GSGYLLRTDAWSYPVLRLKRLGLSKTFRCLVVTLTRRYGVSLIHLDASAECLPGLPTF
                     NW"
     gene            5443..5640
                     /locus_tag="LSX49_004670"
     CDS             5443..5640
                     /locus_tag="LSX49_004670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170962.1"
                     /translation="MKSLTTETALDILIAWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IEQAREDVRAVRHLQLLHQNR"
     gene            5725..6420
                     /locus_tag="LSX49_004671"
                     /pseudo
     CDS             5725..6420
                     /locus_tag="LSX49_004671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309436.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            complement(6484..7239)
                     /gene="istB"
                     /locus_tag="LSX49_004672"
     CDS             complement(6484..7239)
                     /gene="istB"
                     /locus_tag="LSX49_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001522280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc10 family helper ATPase
                     IstB"
                     /protein_id="HBL7170963.1"
                     /translation="MSNIHHLERSLRKLRLTRVGAEWHALEKRALAEGWTPSRYLLTL
                     CNEELLWRESEKLRRYKKEARLPVAKTLSEYDFSQVPELNGAQFRQLCETTDWVDAGE
                     NVLLFGASGLGKSHLAAAIVDGVVGQGYRARFYSAGELLQELRKARAQLKLNELLLKL
                     DRYRVIVVDDLGYVKRDSAETGVLFELIAHRYERGSLVITSNHPFSMWGSIFVDETMA
                     VAAADRLIHHGYMFELKGESYRKKTAKAVTSAT"
     gene            complement(7236..8735)
                     /gene="istA"
                     /locus_tag="LSX49_004673"
     CDS             complement(7236..8735)
                     /gene="istA"
                     /locus_tag="LSX49_004673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc10 family transposase"
                     /protein_id="HBL7170964.1"
                     /translation="MTLNTSQVSYYMTQRKKGITQHISAMKAGISVRSGRRIEKGEWA
                     KNSVRHWRTRKDPLEAVWDSMLVPLLKERPALTPTTLLEMLQDKYPGQYPNSLRRTMQ
                     RRVREWKLQYGAEQEVMFRQRHQPGLRGLSDFTELKGVVVTIAGKLLAHKLYHFRLEW
                     SHWSWMRVVLGGESFSALAEGLQEALGQLGGVPVEHKTDSLRAAWKQQGEDGRRELTE
                     RYAALCQHYGMQGVHNNAGRGHENGSVESAHGHLKRRICQALILRGSNDFSTIEEYQA
                     FITQQVMRHNRNNQDLVKEERLHLKPLPLRRSADYDELTVRVSRSSTINVKHVVYSVP
                     SRLVGQLLRVRLWDDRLSRYVGSSEVMSCPRVRPEKGKTRARRIDFRHVIDSLAKKPG
                     AFCHATLRNDILPDDEWRRLWRRLCNHLEPDMAGRLMVHALKLAAGYDDISVVAKGME
                     QMLNTPGNVDLHRLMRFLGIKEKALPVVNVKQHNLSSYEQLLRGKGGSQ"
     gene            8826..8987
                     /locus_tag="LSX49_004674"
                     /pseudo
     CDS             8826..8987
                     /locus_tag="LSX49_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280511.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            9058..>10000
                     /locus_tag="LSX49_004675"
     CDS             9058..>10000
                     /locus_tag="LSX49_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBL7170965.1"
                     /translation="MFSRLFVKKHTPAMVAGSLIFLFIILLTFFWKKAELVNDSQIRV
                     NFALGYIENILNQNNSISQEAEHLLLNNCNADTQHELSNLLLKRPQLRALSLARQEAV
                     FCSTHPGLPVGPVAEKEQWRHDMLIRFPEDTGTLPWILLRTPYKNGTVITATDYYFIQ
                     DIISVVHAVPAIRFRLGNTVLSASGKNVTLLPDDSGIQKESHSKKYPFSLIYIIPVKM
                     QLTYAWKQAWYMIPVAIFGGILTAFLLSRRRPSSPLDMLKNALAHGEFRPYFQPIISA
                     KNHQLTGCEVLIRWHHPVSGIIPPDQFIPLAESTGLIA"
BASE COUNT         2422 a         2771 c         2422 g         2385 t
ORIGIN      
        1 atgatgcata ataacatcat gaaataaaag atgttttctt acggagtgca catctatgtc
       61 tgataatcgt tcccggcatg atcgcctggc ggttcgctta tcactcatta tcagccgact
      121 gatggccgga gaatctctgt cactaaaaac actgtcagat gaatttggcg ttacagaacg
      181 tactttacag cgcgattttc atcagcgtct ggttcacctg gatttagagt acagaaatgg
      241 caggtacagc ctcagacgac agagcagccc aggtgcgatc cctgaaatgc tttcttttat
      301 acagaatacc gggatcgcac ggatacttcc gctccggaac ggacgactga taacctgtct
      361 taccgacaac caggagccct ctccctgcct tatctggcta ccggcgccgg atatcactgc
      421 aacgttcccc gagtgtttct cgcaactcat cctggcaata agacagtgta tccacatctc
      481 tctgatgact gagcgatggt atccgtcact ggagccctgc cggctcattt attacagcgg
      541 tagctggtat ctgatcgcgt tacagaaggg aaaactgcag gtctttcctc tggcagatat
      601 caaatcagtc agcctgacat cagaacggtt tgaacggaga ggccacatcc acagtctggt
      661 cgctgaagag cgttttatct ccgccctgcc acatttctct ttcatccata aacttatcaa
      721 cacctttaac ctgtgatcgc cggcctgcca aagccgtccc gacaggtatg gagacaatat
      781 gttgaacaga aaactaaata tacggctacg tcattccctg aacagtcact gcataccttc
      841 catcattatc aataacaccg tacgttcatt tcagaggtca gtcatgaata ccagagctct
      901 ttttcccctg ctgttcactg tggcatcatt ctccgcctcc gccggcaact gggctgtcaa
      961 aaacggctgg tgtcagacca tgacggaaga tggtcaggcg ctggtaatgc tgaaaaatgg
     1021 cacgattggt attaccggcc tgatgcaggg atgcccgaat ggcgtacaga cgctcctggg
     1081 cagccgtatc agtattaacg gtaacctgat ccccacatca caaatgtgta atcagcagac
     1141 gggattcagg gctgttgagg tggaaatcgg acaggcgccg gaaatggtca aaaaagccgt
     1201 tcactccata gcagagcgtg atgtgtccgt tttacaggca tttggtgtac gaatggaatt
     1261 cacccgcggt gatatgctga aggtctgtcc gaaatttgtc acatcacttg ccggtttttc
     1321 cccgaaacag acgaccacta ttaataaaga ttccgtcctg caggcagccc ggcaggcata
     1381 cgcccgggaa tatgacgagg aaacaacaga aaccgctgat tttggctctt acgaagtaaa
     1441 aggcaataag gttgagtttg aagtattcaa tcctgaagac cgtgcgtacg acaaagtgac
     1501 cgtcacggtt ggtgctgacg gtaatgccac cggcgccagc gttgaattta tcggaaaata
     1561 gccggtatgt cggactgcca ccctgtttta ttgcccgaag gccctttctc acgcgaacag
     1621 gcggttgccg tcacaacagc ttaccgcaat gtgcttattg aagatgacca gggaacgcat
     1681 ttccggctgg ttatccgcaa tgccgaaggg cagctacgct ggcggtgctg gaattttgaa
     1741 cctgatgccg gaaaacagct aaattcgtat ctcgccagtg agggaattct caggcaataa
     1801 acgtcttcat ttcatccatc aggccgcgtc ttctccggga gacgcggcct tttcgtttat
     1861 accgctaatt cattcataag gagcaaagta tgcaattagc cagtcgtttt ggtcatgtaa
     1921 atcagatccg tcgggagcgc ccactgacac gcgaagaact gatgtaccac gtcccgagta
     1981 tttttggaga agaccggcac acctcccgca gtgaacggta tgcgtacatt cccaccatca
     2041 ccgtcctgga aaatctgcag cgggaaggct ttcagccgtt cttcgcctgc cagacccgtg
     2101 tgcgcgacca gagccgccgg gaatatacca aacatatgct gcgtctgcgg cgggccggac
     2161 agataaccgg tcagcatgtg cctgaaatta ttctgctcaa ctcccatgac ggttcatcca
     2221 gctaccagat gttacccgga tattttcgtg ccatctgcac caatggcttg gtctgcggtc
     2281 agtcgctggg agaagtccgg gtgccccacc ggggaaacgt ggtggacagg gtgattgaag
     2341 gtgcttacga agtggtgggc gtgtttgacc ggattgagga aaagcgtgat gccatgcagt
     2401 cgctggtcct gccgccaccg gcacgccagg cgctggcaca ggcggcgctg acttaccgtt
     2461 atggtgatga acatcagccc gtcaccacta ccgacattct gacgccacga cgccgggagg
     2521 attacggtaa ggacctgtgg agtgcttatc agaccatcca ggaaaatatg ctgaaaggcg
     2581 ggatttccgg tcgcagtgcc agaggaaaac gtatccatac ccgggccatt cacagcatcg
     2641 ataccgacat taagctcaac cgggcgttgt gggtgatggc agaaacgctg ctggagagca
     2701 tgcgctgatg ctgtttccct gaaagtgcag ccctgactca cgtctgtacc agtccccatg
     2761 cattcttcca ttcatttact ttttataagg aatcatctca tgacaacctt ttcgcatagc
     2821 tccaccacac cttctgtttc cgtaactact gcatcaggga ataaccagtc tcaactggtt
     2881 gccactcccg tccctgatga acagcgcatc agcttctggc cgcagcactt tggcctcatt
     2941 ccacagtggg tgaccctgga gccccgtgtc ttcggctgga tggaccgtct gtgtgaagac
     3001 tactgcgggg gtatctggaa tctgtacacc ctgaacaacg gtggcgcatt tatagcacct
     3061 gaaccggatg aagatgatgg agaaacctgg atactgttca atgccatgaa cggtaaccgc
     3121 gctgaaatga gcccggaagc cgccggcatt gcagcctgtc tgatgacgta cagccatcat
     3181 gcctgtcgta cggagtgtta tgccatgacg gtccattatt atcggttgcg ggattacgcc
     3241 ctgcagcatc cggaatgcaa cgccattatg cgcatcattg actgaaaggg gctggaacaa
     3301 tgcaacagct ttcctttctg ccaggagaga tgacgcccgg cgagcgcagc ctcattcagc
     3361 gggccctgaa aaccctggac cgccatcttc atgaacccgg tgtggccttc acctccaccc
     3421 gtgcggcacg ggaatggctg attctgaaca tggcgggact ggagcgtgaa gaattccggg
     3481 tgctgtatct gaacaaccag aataagctga ttgccggtga aaccctcttc accggcacca
     3541 tcaaccgcac ggaagtccat ccccgggaag tgattaaacg cgccctgtac cacaatgccg
     3601 ctgccgtggt actggcgcac aatcacccgt ccggtgaagt cacacccagc aaggcagacc
     3661 gccttatcac ggaacgtctg gtacaggcac tgggcctggt ggatatccgg gtgccggacc
     3721 atctgatagt cggtggcagc caggttttct cctttgcgga acacggtctg ctttaacccg
     3781 tcaccgttac aaccacatca tacctgtttt cgcttttatc ttctgtcttc agaggtatca
     3841 cactatgaaa atcatcaccc gtggtgaagc catgcgtatt caccaacaac atccggcatc
     3901 ccgtcttttt ccgttctgta ccggcaaata ccgctggcac ggcagcactg aagcgtatac
     3961 cggtcgtgaa gtgcaggata ttcccggtgt gctggctgtg tttgcagaac gccgtaaaga
     4021 cagttttggc ccgtatgtcc ggctgatgag cgtcaccctg aactgagtca ggaagggcat
     4081 tctgatgagc cgaattatcg ccaccatcga accattctta actgatttct gtgaggactt
     4141 tatcgtgtca gacacactgc ccgggacaac gcatcccgac gacaatcacg accgcccctg
     4201 gtgggggctg ccctgcaccg tgacgccctg tttcggggca cgtctggtgc aggagggtaa
     4261 ccggttgcat taccttgccg accgtgccgg tatcagaggc cggttcagcg acgcggatgc
     4321 ataccacctg gaccaggcct ttccgctgct gatgaaacaa ctggaactca tgctcaccag
     4381 cggtgaactg aatccccgcc atcagcatac catcacactg tatgcgaaag ggctgacctg
     4441 cgaagccgat acccttggca gttgtggtta cgtttatctg gctgtttatc cgacaccggc
     4501 agcgcccgca atcaccgtat aaccccggat atctcccctt tatcaccacc tgttacagag
     4561 aacttaagat gaatacatta cccgacactc acgtacggga ggcatcgggc tgcccgtctc
     4621 ccgtcaccat ctggcagaca ctgctcaccc gactgctgga ccagcactat ggcctcacgc
     4681 tgaatgacac accgttcgct gatgaacgtg tgattgagca gcatattgag gcagggattt
     4741 cactgtgtga cgcggtgaac tttctcgttg aaaaatacgc gctggtacgt accgaccagc
     4801 cgggattcag cgcaggagcc ccgtcgcagt taatcaacag cattgatatt ctccgggctc
     4861 gcagggcaac cggcctgatg acccggaaca attacagaat ggtaaataac attacccagg
     4921 gcaagcatcc ggaggcaaaa caatgaaact ggccctgacg ctggaagccg acagcgttaa
     4981 cgtgcaggca ctgaacatgg ggcgcattgt cgttgacgtc gatggtgtta atctcagtga
     5041 actgattaac aaggtctctg aaaacggtta tttactccgc gtggtcgata aatccgacca
     5101 acacgcaacc agtacaccac caccgttaac aacccttacc tgcatacgtt gcagcaccgc
     5161 acatatcacg gaaacggaca acgcctggct gtactcgctg tcacaccaga ctaatgacga
     5221 cggcgaatca gaatggattc attttacagg cagcggctat ctgttacgta ccgatgcgtg
     5281 gtcatacccg gttctgcggc ttaagcgcct gggcctgtca aaaacgttcc gttgtctggt
     5341 tgtcacactt acccgacgtt atggcgtcag tctcattcat ctggatgcca gcgctgaatg
     5401 cctgccgggt ttacccactt tcaactggta accaggaaca acatgaaatc attaaccacg
     5461 gaaacagcac tggatattct gattgcgtgg ctgcaggaca atatcgactg tgaatccggg
     5521 attatcttcg acaacgatga ggataagacg gattcagcag cactgttgcc ctgcatcgaa
     5581 caggcccggg aggatgtccg tgctgttcgt catctgcagc ttctgcacca gaaccggtga
     5641 atatcactca ccatacttca ttcccctgac gccagcctga atacagctgg cgttttcgtc
     5701 tataaaccaa aaggaaaacc gataatgtca gacatcacaa tctcccgtcc ggaagtggtc
     5761 accgggcata cggacgttat ctgctccacc agtatccgac acgttgtgac ggtacggaat
     5821 gcagcactgc aacaaaccga aacgcttatc cggcaactgg cagaaatctc agtgctgaca
     5881 gcaggcattg gcggcaaaac cgccctggac tgggcgatga aacagaattt tcgctgtggc
     5941 tgctggctga tggaaaaacc ggaagcagca atgaaagcca tcacccgcaa tctcgatcga
     6001 gaaatctggc gtgacctgat gcaacgttca gggatgcttt ccttaatgga tgcacaggcc
     6061 cgtgatacat ggtaccgatc actggaatat gataattttc cggaaatcag tgaagcgaac
     6121 attctgagca catttgaaca actgcaccag aacatagatg aagtgtttga gcgaggggtg
     6181 atcaacgtct tcaggggact gaactggaat tacaaaacta attgcccctg taaatttggc
     6241 agtaaaatta tcgtcaacaa tctggtgaga tgggaccggt ggggatttca tcttatcacc
     6301 gggcaacagg cagatcgact tgccgacctg gaaagaatgc tgtatttgtt cagcggcaaa
     6361 ccgattcctg acaaccggga aaacataacc attcatctgg atgatcacat ccactcagta
     6421 ttagacgtca actagttttg ccgactcgcg ccaactatac tggccgcacc cttcagtgcg
     6481 acatcaagtc gcgcttgtta ctgccttcgc tgtctttttc ctgtagcttt cacctttcag
     6541 ttcgaacata tatccgtgat ggatcagccg gtctgccgcc gccaccgcca tagtctcatc
     6601 cacgaagatg ctgccccaca tgctgaacgg atggttactg gttatcacca ggctcccacg
     6661 ttcatagcga tgcgctatta actcgaacag tactcccgtt tcggcgctgt cgcgtttgac
     6721 atagccaaga tcatccacca ctatcacccg gtagcgatcc agtttcagta gcagctcatt
     6781 cagtttcaac tgcgctctgg ctttacgtag ttcctgcaac aactctcctg cgctgtagaa
     6841 ccgggcccgg tagccctggc ctactacgcc atccacgatc gctgccgcca gatggctttt
     6901 ccccaacccg ctggctccga acagcagaac gttttctcct gcatcaaccc agtctgtcgt
     6961 ttcacagagt tgccggaact gagctccatt cagttccggc acctgactga agtcgtattc
     7021 gcttagcgtt ttggcaactg gcaaccgggc ctccttttta taacgacgca gtttttcact
     7081 ctcgcgccac aggagttctt cattgcatag cgtcagaaga tagcgcgatg gtgtccagcc
     7141 ttctgccagt gctcgttttt ccagagcgtg ccattcagct ccaactcgtg tcaggcgtag
     7201 tttacgcagg ctgcgttcaa ggtgatggat attgctcact gcgaacctcc cttgccacgc
     7261 agtagttgct cataactgct caggttatgc tgtttcacat tgactaccgg caacgccttt
     7321 tcctttatac ccaggaagcg catcagccgg tgcagatcca cgtttcccgg ggtattcagc
     7381 atctgctcca taccttttgc cacgactgag atatcgtcgt atcctgcagc cagtttcaga
     7441 gcatgtacca tcagcctgcc tgccatgtcg ggttccagat gattacataa gcgacgccac
     7501 agcctccgcc attcatcgtc tggcaggatg tcatttctca gcgttgcatg gcagaacgca
     7561 ccgggctttt ttgccagact gtcgatcaca tgtcggaagt cgatacgacg ggcccgcgtc
     7621 ttcccttttt ctggtctgac acgtgggcag ctcatgacct cgctgctgcc aacgtaacgg
     7681 ctcagacgat cgtcccataa ccggacccgt aacagttgac ctacaagccg ggaaggtacg
     7741 ctgtagacga cgtgcttcac attgatggta ctgctgcggc taaccctcac agtcagctca
     7801 tcatagtcag cactgcgacg aagcggcagc ggtttcagat gaagacgttc ttccttgacc
     7861 agatcctgat tgttacggtt gtgccgcata acctgctgag tgatgaaggc ctgatattct
     7921 tctatggtgc tgaagtcgtt actgccccgc agtatcagcg cctgacagat acgccttttc
     7981 agatgtccgt gggcactttc aaccgagcca ttttcgtggc cccgaccggc attattgtgt
     8041 acgccctgca ttccgtagtg ctgacagaga gcagcataac gctcagtcag ctcgcggcgt
     8101 ccatcttcgc cctgttgttt ccatgctgcc ctcaggctgt ccgttttatg ttctaccggc
     8161 actccgccca gttgtccgag ggcttcctgc agaccttcag ccagagcaga gaagctctca
     8221 ccacccagca caacccgcat ccagctccag tggctccatt ccagacggaa gtgatacaac
     8281 ttatgcgcca acaacttacc ggcgatggtg acaactacac ctttcagttc agtaaagtcc
     8341 gacagacctc gcagaccggg ctgatgtcgc tggcggaaca tgacctcctg ctctgcacca
     8401 tactgtagct tccattcgcg gacccgccgt tgcattgttc ttcgaaggct gttggggtac
     8461 tggccgggat atttatcctg tagcatctcc agcagagttg ttggtgtcag agccggcctc
     8521 tctttcaaca gaggaacaag catgctgtcc cacacagctt ccagaggatc tttgcgtgtg
     8581 cgccagtgcc gaacactgtt ttttgcccac tctccttttt cgatccgacg accagaacgg
     8641 actgagatac cagccttcat ggccgagata tgctgagtta tacctttctt acgctgagtc
     8701 atatagtaac tgacctgaga agtattgagc gtcacgccat ttcctgttgg atcatgtaaa
     8761 tgacactcag gttacaaaac cggccagaat aatcggcgcc aggcggactg agttattgtc
     8821 gtctcataca ctcagttcag ggtaaagcgt gctatgaaga tgagatgttc agcatcagat
     8881 actttaagaa gggctccgcg cacatcacgt tcaggaaacc agagctggtt gacagattga
     8941 atgatattat tgcgaaatac tatccggaaa ccttatcgcc cgtttaaccc aaagcacaga
     9001 ctcagtacat acacaaaaac attctgataa atctggcgtc attcagagca aaaaaacatg
     9061 ttttccagat tatttgtaaa aaaacatact ccagctatgg tggcaggtag tctgatattt
     9121 ctgttcatta ttctgctgac atttttctgg aaaaaagcag agctggtgaa tgacagccag
     9181 atcagagtta atttcgcact tggctatata gaaaacattc tcaatcagaa caacagcatc
     9241 agccaggaag cagaacattt gcttctgaat aactgtaacg cagatactca gcatgaatta
     9301 agcaatctgc tgctgaaacg cccacaactt cgtgcactga gcctggcaag acaagaggct
     9361 gtattttgta gcacccaccc cggtttacct gtcggtccag ttgctgaaaa ggaacagtgg
     9421 cggcacgata tgctgattcg ttttcctgaa gatacaggta ctctgccctg gatcctgtta
     9481 agaacacctt acaaaaacgg cacggtcatt accgccacgg attattattt tattcaggac
     9541 atcatctctg tggttcatgc ggttcctgca atacgattcc gtttgggaaa cacggtcctg
     9601 tcagccagcg gaaaaaatgt cactctgctc ccggacgaca gcggtataca aaaagaaagt
     9661 cattcaaaaa aatatccgtt ctccctgatt tatatcatcc cggtgaaaat gcaacttacc
     9721 tacgcctgga aacaggcctg gtatatgatc cctgttgcca tcttcggtgg aatactcaca
     9781 gcctttctgc tgtcccgccg acgtccatct tccccgctcg atatgctgaa aaatgcactt
     9841 gctcacggag agttcagacc ttattttcag cccatcattt ccgctaaaaa tcaccagcta
     9901 accggctgcg aagtactgat tcgctggcat caccccgtca gcggaattat cccaccagat
     9961 cagtttatcc cgctggcaga gtccaccgga ttaattgccc
//
LOCUS       DAFGPF010000162         9843 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFGPF010000162 DAFGPF010000000
VERSION     DAFGPF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9843
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.162"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..414)
                     /gene="folK"
                     /locus_tag="LSX49_004676"
     CDS             complement(<1..414)
                     /gene="folK"
                     /locus_tag="LSX49_004676"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBL7170966.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESRILAVSSFYRTP
                     PLGPQDQPDYLNAAVALKTTLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVF"
     gene            complement(411..1829)
                     /gene="pcnB"
                     /locus_tag="LSX49_004677"
     CDS             complement(411..1829)
                     /gene="pcnB"
                     /locus_tag="LSX49_004677"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HBL7170967.1"
                     /translation="MTLPRCTIFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQH
                     AISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEY
                     HLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLL
                     ETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDE
                     EPSPRRRTRRPRKRAPRREGTT"
     gene            complement(1868..2794)
                     /gene="gluQRS"
                     /locus_tag="LSX49_004678"
     CDS             complement(1868..2794)
                     /gene="gluQRS"
                     /locus_tag="LSX49_004678"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001432381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HBL7170968.1"
                     /translation="MLPPYFLFKEMTDTHYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWL
                     HEQGLSYYCTCTRARIQNIGGIYDGHCRDLHHGPDNAAVRIRQQHPVTQFTDLLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALHFLGQQVETHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     gene            complement(2831..3286)
                     /gene="dksA"
                     /locus_tag="LSX49_004679"
     CDS             complement(2831..3286)
                     /gene="dksA"
                     /locus_tag="LSX49_004679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HBL7170969.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3464..4168)
                     /gene="sfsA"
                     /locus_tag="LSX49_004680"
     CDS             complement(3464..4168)
                     /gene="sfsA"
                     /locus_tag="LSX49_004680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBL7170970.1"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAIICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     LSAEGMALKKSLPVTL"
     gene            complement(4183..4713)
                     /gene="thpR"
                     /locus_tag="LSX49_004681"
     CDS             complement(4183..4713)
                     /gene="thpR"
                     /locus_tag="LSX49_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HBL7170971.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYTVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            4787..7216
                     /gene="hrpB"
                     /locus_tag="LSX49_004682"
     CDS             4787..7216
                     /gene="hrpB"
                     /locus_tag="LSX49_004682"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HBL7170972.1"
                     /translation="MSSLPVAAVLPELLAALDGASQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDEAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLTSRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLVTQRVSQASMTQRAGRAGRLEPGICLH
                     LIAKEQAERAAAQSEPEILQSDLSCLLMELLQWGCSDPAQMSWLDQPPTVNLLAAKRL
                     LRMLGALDGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFLRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPRLAGAYADRIARRRGQEG
                     RYQLANGMGAMLDADDALSRHEWLIAPLLLQGSSSPDARILLALPVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLATLETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWVMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEASN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            7310..9835
                     /gene="mrcB"
                     /locus_tag="LSX49_004683"
     CDS             7310..9835
                     /gene="mrcB"
                     /locus_tag="LSX49_004683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HBL7170973.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQQPAQQEQKDSDGVAGWIKEMFGSN"
BASE COUNT         2260 a         2510 c         2815 g         2258 t
ORIGIN      
        1 aaagaccagc tccggcgcaa tttcaaacag tggccacagc ataaagccac gatttttcat
       61 atcgtagtgc ggaacggtca gacgttcggt atttattact tcattaccaa acagcatgat
      121 gtcgagatcc agcgtgcgcg gtccccagcg ttcagcttta cggacgcgac cttgctgcaa
      181 ttcgatacgc tgtgtgtgat tgagtagctc ttcaggggca agagtggttt tcagcgcgac
      241 ggcggcattt aagtaatcgg gttgatcttg cggccccaga ggtggggtgc ggtaaaacga
      301 agaaacggca agaatgcggc tttctggaat atcgcctaat gctttcaggg cagcattgac
      361 ctgctccagc ggagaggcca gattgctgcc tatggcaata tacgccactg tcatgtagta
      421 ccctcacgac gcggtgcgcg tttgcgtgga cgacgagtac gacgacgcgg tgacggttct
      481 tcatccagtt cgttaagcat ccctttttgg tctggcggcg cggaaacctg gaactcaccc
      541 caccatttca ccagacgttg cagttcagcg ttacgctcaa cttcggctcg taaggccaac
      601 aggtcgtatg ccgcacggaa cttaggatgc tccagcagtt tccatgcgcg tttaccctga
      661 cgacgggaca tacgcaactg caactgccag atatcgcgag ttagcgtagt cagacgtttc
      721 gggatcgcca gtgaacggca ggcttcgtcc agcacgtcgt tcatcgccag tgcgaaagcg
      781 tcgtgatagg tcaggccgct ctcctgagca attttctgtg ccgtctccag caatgggtac
      841 cagaacatgg cggcaaacag gaacgccggg ttcacgcgca tatcgttatg gatacgcgta
      901 tcggtattct tcagtacctg ctcaataatg cgttccatcg ggctgtcgcc attttccgtg
      961 aagtagcggg taatggtcgg gaacagcggc tggaacagat gatattcaca cagcagctta
     1021 taggtttcgt aaccgtagcc cgcttgcaac agtttcagcg attcttcaaa cagacgtgcc
     1081 ggtgggatat cgttcagtaa ggttgccagg cgtgggatcg gctcggcggt ttccgggctg
     1141 atgcgcatgc ccaatttggc ggcaaaacga accgcgcgga gcatacgtac cggatcttca
     1201 cggtagcgcg tttccgggtt accaatcaga cggataacgc cgtctttcag atccttcatg
     1261 ccgccaacgt aatcacggac ggtaaaatct gccacgctgt aatacaggct gttgatagtg
     1321 aaatcgcggc gctgggcgtc ttcttcgatg gagccgaaaa tgttgtcgcg cagcaacata
     1381 ccgttttgcc cgcgttggga ggtcgtgcgg tcgctgacgt taccttcgtg atgtccacgg
     1441 aaggtcgcaa cttcgataat ctccgggcca aacatcacat gagccagacg gaaacggcga
     1501 cccaccagac ggcagttacg gaacagttta cgtacctgtt caggcgtggc gttagtggtt
     1561 acgtcaaaat ctttcggctt tttgccaagt aacaggtcgc gcacgccgcc gccaaccagc
     1621 caggcttcgt atcccgcttt attgagcctg tacattacct tcagggcatt ttcactgata
     1681 tctttgcggg aaatagcatg ctgctcacgc gggatcaccg tcacctgtgg acgggcgact
     1741 gcctgttcag cctcgctttc ctcgcggctt agcaccttgc ggcaaaaatt agcgactcgg
     1801 gtaaaaatag tacacctcgg tagtgtcaaa catcattcag gacaaaaaaa tagcggctaa
     1861 tcatagctca gcatgacgca tttgagaatg ttgaatttac aattgccgac tcaggcactg
     1921 cggtgagccg ccagtttttg acggctgact gaaggatttg ctcgacgctg aaatcctgcc
     1981 agtgtgtttc tacctgctga cccagaaaat gaagtgccgc gattaacacc gggcgcggat
     2041 cgcctttcgg caacgcaggc gcatgattct gcttggaaag tttagcgcct tgtggattaa
     2101 gcgccagcgg taaatggatg taatctggca ctttccagcc aaaaagctgg tacagcgaga
     2161 tttgccgcac agtcggttcg atcaaatctg ccccgcggac aatttcgctc acgccctgga
     2221 agtgatcatc caccaccacc gccaggttat aggcaaacaa accatcacgg cgatgaataa
     2281 taaaatcttc ccgtgccagt ttttcgtcgg cgtgaataat gcctcgcagc aggtcagtaa
     2341 actgggtgac tggatgctgc tggcggatac gtactgcggc gttgtctggt ccatgatgca
     2401 aatcccggca atgaccgtcg taaataccgc caatgttttg aatacgcgca cgcgtgcagg
     2461 tgcagtaata acttagtcct tgctcatgta accaggcgag tgcttcgcga taggcgtggt
     2521 gacgttgcga ttgccagaga acgtcgccgt cccagtgtag gccgtaatgt tccagctggc
     2581 gcaggatagt ctctgcggca ccgggaactt cacgaggcgg gtcgatatct tcaatgcgta
     2641 ccagccagcg accttgccgg gcgcgagcct gcaaatagct gccaagcgca gcaatcagag
     2701 aaccaaaatg aagctcgccg gaaggagagg gggcgaagcg accaatatag tgtgtgtctg
     2761 tcatctcttt gaacaaaaaa taaggcggga gcatttcccg cctgtggtaa acatgatgga
     2821 acggctgtaa ttagccagcc atctgttttt cgcgaatttc agccagcgtc ttgcagtcga
     2881 tgcatagatc ggctgtcggg cgcgcttcca gacggcgaat accaatttca acaccgcagg
     2941 attcgcagta gccgaaatct tcgtcttcca cttttttcag cgtcttctcg atctttttga
     3001 tcagcttacg ctcgcgatcg cggttacgca gttcgaggct gaactcttct tcctgggctg
     3061 cacggtctac cgggtccggg aagttggctg cttcatcctg catatgtgta acggtgcgat
     3121 cgacttcatc cctgagttga ttacgccatg cttccagaat acgacggaag tgcgccagct
     3181 gggcttcatt catatactct tcgcccggct tctcctgata tggttccacc ccagcgatgg
     3241 cgagaatact cagggacgat gttttacggt tttgcccttc ttgcatgttg cttctcctta
     3301 acacgcacta tcgatcccca tgttcggggg aaaaatgagg ccgctataaa tagcagatgc
     3361 ttttccggat agcaattatc taaacgtaac acttgacaac tgtgtgagga aaagcgtatt
     3421 tgcgcacgcg accagaatgt aaattaacca gttacttact ctactacaat gtaaccggta
     3481 gtgatttttt aagagccatg ccttcggcag aaagttccgc tttgtaagcc agaatttcta
     3541 cccccctctg ttgagcttct gacaatagtt gtgcgtattt ctcatcgatg tggcgcgcgg
     3601 gtgaaaaccg tgtaatggct gaatgcagca cggcgaaaaa gataaccgca cgctggcctt
     3661 cagccgctac gctcatcaac tcccgaaggt gtttctgacc tcgttcagtg accgcatcgg
     3721 gaaaatatcc ctgttcgttc tccgctaacg taaccgattt cacttcaata tagcagtctg
     3781 gacgcgaatc cgcctgcaac ataaagtcaa tacggctgcg ttcggcgccg tattttactt
     3841 cgcttttcag cgagctatag cctgacagct ctgaaattga ttcattaagg atagcctctt
     3901 tcgtcaacct gttagcccaa agcgtattga cgcaaataat tgcgccgctt tggctttgag
     3961 ttaattccca ggtgtgtggg tatttccgtt tggtgttgtc tgaagtcgaa taccagacgg
     4021 tatcgccagg cgttgcacaa ccggtcatcg cacccgtatt cgggcagtgt agcgttaatt
     4081 cgcgaccatc gggtgtgatc acatcggcta aaaaacgttt gtaacgctga attagcgtcg
     4141 cgcgctgtag agggggagaa aattccattg cgacaatcct tgttattgcg ttagcgccca
     4201 gcgttttagc ggcgtgtagc gtgtgcgtcc acgggcaaac gaggaggcgt aaagggtgaa
     4261 ctccgtcacc gtatacgacc agttaaaacc tggcggcggg attgtcaccg cctcgctggc
     4321 gtcgcgcaat aaggtaatat gtggatgaaa cggacgattg ctttgaaaac aaccgctgcg
     4381 ggcagcctgt gaacggagca tattcgccag ctggattaag ccgcgtggcg gctgtcgcat
     4441 ccctaaccac accacacgcg aacgcagcca ttgaccggcg tcatcaagcg tgagtgtgaa
     4501 accaggttga cgaatccgtc cggctaaaag agaaagcgcc ttctctttct ctgcgctcac
     4561 ttcgcctaaa aatgccagag tcagatgcaa attatcggcg gcgaccggac gtcccgcctc
     4621 aggtgggaag tgtgtggcgc gccagtggat aatctgttcg cggatttctg caggtaagtc
     4681 gatagcaaag aacagccgtt gcggttcaga catgtgaggc actcggttat gaattaccgc
     4741 gatgctacaa tgtggcgcga agaatgttaa ccctctggag cgttttgtgt cgtcgttgcc
     4801 cgttgctgcc gtcttacctg agttacttgc tgccctcgat ggtgcatcgc aggtgttatt
     4861 aagtgcgccg accggggccg ggaaatcaac ctggctgccg ctgcaactgc tggcgcatcc
     4921 cggcattaac gggaaaatta tcctgctgga gccgcgtcgt ctggcggcgc gtaacgttgc
     4981 gcaacgactg gcggagctgc ttaacgaaaa gccaggcgat accgttggct accggatgcg
     5041 tgcgcaaaac tgcgtcgggc cgaatacccg cctggaagtg gttaccgaag gcgtgctgac
     5101 gcggatgatc cagcgtgacc cggaactgag cggtgttgga ttggtgatcc ttgatgaatt
     5161 tcatgagcgc agcttgcagg cggatttggc gttggcgctg ttactcgatg tgcaacaagg
     5221 tctgcgtgat gaccttaaac tgctgattat gtcggctacg ctggacaacg accgcttgca
     5281 gcaaatgctg ccagaagcgc ccgtcgtcat ctcagaaggg cgctcgtttc cagttgaacg
     5341 ccgttatttg ccgctgcccg ctcatcagcg ttttgacgaa gccgtcgcgg ttgccaccgc
     5401 cgaaatgctg cgtcaggaaa gtggatcatt actgttattt ttacctggcg tcggagaaat
     5461 tcagcgtgtg caggaacaac tgacttcacg catcggcagt gatgtgttgc tctgcccgct
     5521 gtatggcgcg ttgtcgctga acgatcagcg aaaagcgatc ctcccggcac cgcaagggat
     5581 gcgtaaagtg gtgctggcga ccaatattgc tgaaaccagt ttaaccatcg aaggtattcg
     5641 tctggtggtg gattgtgccc aggagcgtgt ggcgcgtttt gatccgcgta cagggcttac
     5701 gcggctggtt actcaacgtg ttagtcaggc gtcgatgacg caacgtgccg ggcgtgccgg
     5761 gcgtctggag ccgggtatct gcctgcattt aatcgccaaa gaacaagcag aacgcgctgc
     5821 cgcgcaaagt gaaccggaaa tattacaaag cgatctttcc tgtttgctga tggaattact
     5881 gcaatgggga tgcagcgatc cggcgcagat gagctggctg gatcaaccgc caacggtgaa
     5941 tctactggcc gcgaaacgcc tgttacggat gctgggggcg ctggacggtg aacggcttag
     6001 tgcgcaaggg caaaaaatgg cagcgctggg taacgatccg cgtttagcgg caatgctggt
     6061 tagcgcgaag aacgacgacg aagctgctac cgcggcaaaa attgccgcca ttctcgaaga
     6121 gccgccacgg atgggcaata gtgacctggg cgtggcgttt ttgcgcaatc aacccgcctg
     6181 gcagcaacgt agtcagcaac tgttaaaacg tttaaacgta cgcggcggtg aggcagacag
     6241 ttcgcttatc gcgccgcgac ttgccggagc gtatgccgat cgtattgctc gccgccgtgg
     6301 gcaagaggga cgctatcaac tggcgaacgg catgggggcg atgctcgatg ccgacgatgc
     6361 gcttagccgc cacgaatggt tgatcgcgcc gttattattg cagggcagtt cttcgccgga
     6421 tgcgcggatt ttactggcgc tgccggtcga tattgatgag ttagtacaac gctgcccgca
     6481 gctggtacag cagtctgaca ccgtggagtg ggatgacgcg caaggtacgc tgaaagcctg
     6541 gcgtcggctg caaatcggtc agttgacggt aaaagtgcaa ccgctggcga aaccctcgga
     6601 agacgagttg catcaggcga tgcttaacgg cattcgtgat aaaggtttaa gcgtgctcaa
     6661 ctggacggcg gaagcggaac agctacgctt gcgtttgtta tgtgccgcaa agtggttgcc
     6721 ggaatatgac tggccagcgg ttgatgatga aagtttgttg gcgacgctgg aaacgtggct
     6781 actgccgcat atgacaggcg tacattcgct acgcggcctg aaatcactcg atatttatca
     6841 ggcactgcgt ggattacttg attgggtaat gcagcaacgt ctggatagtg aattgcctgc
     6901 gcattacact gtgccgacgg gaagccggat cgccattcgt taccatgaag ataacccgcc
     6961 cgcgctggcg gtgagaatgc aggagatgtt tggtgaggcc tctaatccga ctatcgccca
     7021 ggggcgcgta ccgttggtgc tggagttgct ttcccctgcc caaaggccgc tgcaaatcac
     7081 gcgtgatttg agcgccttct ggaaaggagc gtaccgtgag gtgcaaaaag agatgaaagg
     7141 gcgttatccc aaacatgtct ggccggacga cccggcaaac accgcaccga cgcgacgaac
     7201 gaaaaagtat tcgtgaagac caaagcaaat ttgagagata tcttcttctg tcttgcaaca
     7261 gaagaacaga aaatcgggct tttgcgcctg aatattgcgg agaaaaagca tggccgggaa
     7321 tgaccgcgag ccaattggac gcaaagggaa accgacgcgt ccggtcaaac aaaaggtaag
     7381 ccgtcgtcgt tacgaagatg acgatgatta cgacgattat gatgactatg aggatgaaga
     7441 accgatgccg cgcaaaggta agggcaaagg caaagggcgt aagcctcgtg gcaaacgcgg
     7501 ctggctatgg ctgctgctaa aactggctat cgtttttgcc gtgctgatcg ccatttacgg
     7561 cgtttatctc gatcaaaaaa ttcgcagccg tattgatggc aaggtctggc aattgcccgc
     7621 ggcagtttat ggtcgaatgg tcaaccttga gccagacatg accatcagca agaacgagat
     7681 ggtgaagctg ctggaggcga cccagtatcg ccaggtgtcg aaaatgaccc gtcctggtga
     7741 gtttaccgta caggccaaca gcattgagat gatccgccgt ccgtttgatt tcccggacag
     7801 caaagaaggg caggtgcgcg cgcgtctgac ctttgatggc gatcatctgg cgacgatagt
     7861 caatatggag aacaaccgtc agttcggttt cttccgtctt gatccgcgcc tgatcaccat
     7921 gatctcttcg ccaaacggtg agcagcgtct gtttgtgccg cgcagtggtt tcccggattt
     7981 gctggtggat actttgctgg cgacagaaga ccgtcatttc tacgagcatg atgggatcag
     8041 tctctactca atcggacgtg cggtgctggc aaacctgact gccggacgca cggtgcaggg
     8101 ggcgagtacg ctgacgcaac agttggttaa aaacctgttt ctctccagcg agcgttctta
     8161 ctggcgtaaa gcgaacgaag cctacatggc gctgatcatg gacgcgcgtt acagcaaaga
     8221 ccgtattctt gagctgtata tgaacgaggt gtatctcggt cagagcggcg acaacgaaat
     8281 ccgcggcttc ccgctggcga gcttgtatta ctttggtcgc ccggtagaag aattgagcct
     8341 cgatcagcag gcgctgttgg tgggtatggt gaaaggggcg tccatctaca acccgtggcg
     8401 taacccgaaa ctggcgctgg agcgacgtaa cctggtacta cgtttgctgc aacagcaaca
     8461 aattattgat caagaactct atgacatgtt gagtgcacgt ccgctgggtg ttcagccgcg
     8521 cggtggggtg atctctcctc agccagcctt tatgcagctg gtgcgtcagg agctgcaggc
     8581 gaaattaggc gataaggtaa aagatctctc cggcgtgaag atcttcacta cctttgactc
     8641 ggtggcccag gacgcggcag aaaaagccgc cgtggaaggc attccggcac tgaagaaaca
     8701 gcgtaagttg agcgatcttg aaaccgcgat tgtggttgtt gaccgcttta gcggtgaagt
     8761 tcgtgcgatg gtcggtggct ctgagccgca gtttgcgggc tacaaccgtg cgatgcaggc
     8821 gcgtcgttcg attggttccc ttgcaaaacc agcgacttat ctaacggcct taagccagcc
     8881 gaaaatctat cgtttgaata cgtggattgc cgatgcgcca atcgcgctgc gtcagccgaa
     8941 tggccaggtc tggtcaccgc agaacgatga tcgtcgttat agcgaaagtg gcagggtgat
     9001 gctggtagat gcgttgaccc gttcgatgaa cgtgccaacg gtgaatctgg gcatggcgtt
     9061 ggggctgcct gcggttacgg atacctggat caaactgggt gtgccgaaag atcaactgaa
     9121 tccagttcca gcaatgttgt tgggggcgtt gaacttaacg ccaatcgaag tggcgcaggc
     9181 cttccagact atcgccagcg gtggtaatcg tgctccgctt tccgcgctac gttcagtcat
     9241 cgcagaagac ggcaaggtgt tgtatcagag cttcccgcag gcagaacgcg ctgttccggc
     9301 gcaggcggcg tatctgacac tatggaccat gcagcaggtt gtacaacgcg gtacgggacg
     9361 tcagcttggg gcaaaatacc cgaacctgca tctggcaggg aaaacaggga ctaccaacaa
     9421 taacgtagat acctggtttg cgggcattga tgggagcacg gtgaccatca cctgggtcgg
     9481 ccgtgataac aaccagccga ccaaactgta tggtgccagc ggggcaatgt cgatttatca
     9541 gcgttatctg gctaaccaga cgccaacacc gctgaatctt gttccgccgg aagatattgc
     9601 agatatgggc gtggactacg acggcaactt tgtttgcagc ggtggtatgc gtgtcttgcc
     9661 agtctggacc agcgatccgc aatcgctgtg ccagcagagt gagatgcagc agcaaccgtc
     9721 aggcaatccg tttgatcagt cttctcagcc gcagcaacag caacctgctc aacaggagca
     9781 aaaagacagc gacggcgtgg ctggctggat caaggagatg tttggtagta attaatatcg
     9841 taa
//
LOCUS       DAFGPF010000163         9711 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFGPF010000163 DAFGPF010000000
VERSION     DAFGPF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9711
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.163"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            94..594
                     /gene="tssB"
                     /locus_tag="LSX49_004684"
     CDS             94..594
                     /gene="tssB"
                     /locus_tag="LSX49_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HBL7170974.1"
                     /translation="MADSFQNEVPAARVNIKLDLHTGNAKKKVELPLKLLAVGDYSNG
                     KEQRPLSERDKIDINKNNFNSVMAEFSPAVNLTVEDTLNGNGNEQNIALEFKSLKDFE
                     PEQVAKNIPQLRVLLAMRNLLRDLKSNLLDNATFRRELENILKDPTLSSELRDELAKI
                     APQENV"
     gene            653..2191
                     /gene="tssC"
                     /locus_tag="LSX49_004685"
     CDS             653..2191
                     /gene="tssC"
                     /locus_tag="LSX49_004685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HBL7170975.1"
                     /translation="MSVQQEHATSETATLTTTESGGVYQSLFDKINLTPVSSIQEIDS
                     WQNSETLADASPDERVTAAIHVLLSCLAKSGEDVVKLDKSLLDFHIDDLDQKISKQLD
                     AVMHHPEFQKVESLWRGTWFVVQRTDFRKNVRIELLDVSKEHLRQDFDDSPEIIQSGL
                     YRHTYIQEYDTPGGEPVASLISSYEFDNSPQDIALLRNISRVSAASHMPFIGSVGPKF
                     FLKNSMEEVAAIKDIGNYFDRAEYIKWKSFRDTDDSRYVGLVMPRVLGRLPYGPDTVP
                     VRSFNYVEEVKGPDHEKYLWTNASFAFAANMVKSFVNNGWCVQIRGPQAGGAVADLPI
                     HLYDLGTGNQVKIPSEVMIPETREFEFANLGFIPLSYYKNRDYACFFSANSAQKPALY
                     DTADATANSRINARLPYIFLLSRIAHYLKIIQRENIGTTKDRRVLELELNTWIRTLVT
                     EMTDPGDELQASHPLRDGKVIVEDIEDNPGFFRVRLFAVPHFQIEGMDINLSLVSQMP
                     KAKA"
     gene            2209..3546
                     /gene="tssK"
                     /locus_tag="LSX49_004686"
     CDS             2209..3546
                     /gene="tssK"
                     /locus_tag="LSX49_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HBL7170976.1"
                     /translation="MKIHRPLWAEGTFLSSQQFQQQARWEAFSNDSIAQLCIRHPWGI
                     ANVLFDRDALTSGKLKTQAVRLRFADGTLIDSDVSDVLPLACDLRALKNDSAIVLLAL
                     PLAHGNGGNLGQGEQTERPLRYRQEWQKVQDIYGSDSEDMAVERHALSLRFAHDNNQD
                     YITCPLARLVRDVQGNWTQDESYIPPLLAFNAHDGLVQRLDTLLLQLRAKCQRLMAMR
                     RESNQRMADFAVADVSLFWLLNALNSAEPVLSDFLRYPAVHPELVWRELARLAGALLT
                     FSLEHNVSAVPPYVHESPSIVFPPLFSLLSELLEASLPSRVIALDLASLPGNRWKADL
                     HDPRLREEADFYLSVRSSLPAHQVLHQLPLVCKIGAPDDVTLLINVALNGVPLVPLTS
                     VPAALPLRLENQYFALDMHSDAAKSMLESGCCMIYAPGTMGDLKPELFAVLRT"
     gene            3543..4208
                     /gene="tssL"
                     /locus_tag="LSX49_004687"
     CDS             3543..4208
                     /gene="tssL"
                     /locus_tag="LSX49_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssL, short
                     form"
                     /protein_id="HBL7170977.1"
                     /translation="MKKETDINIDALLRDTFLTVVELRQGTTVRHGMELYRHCQRQVE
                     LVRERLKDAGFSRESVEHITYAQCALLDETVLSRGGMDDGQAIWMKDPLQSHFFNTLQ
                     AGELLYERMKQVLQEPAPAQAVLTCFHRVLLLGFRGRYQDPAAPERDQLISTLNGQVA
                     PFGVLPETAVLNVPLSPRQHPLLHSPFFWLVTLTLVLAGVWWGLHYWLNVLVDELLPQ
                     SLR"
     gene            4221..5873
                     /locus_tag="LSX49_004688"
     CDS             4221..5873
                     /locus_tag="LSX49_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBL7170978.1"
                     /translation="MRNALKQTVLLWTLLLLLTTWLGFFAVSAVVKYAVVVILVAVTA
                     AVMAYWHKKKGQVVADDVWPSSLPPETYRQPVVLVCGDMSAHLFTDSPVRQVSEGLYL
                     PVSDEEQLVAQVERLLTLRPAWASQFAVAYTVMPGMYRDAAVLTGQLRRFAHSMATVR
                     RRAGVNVPWLLWSGLSGSPLPERANSPWFICTGGEVQVATSAETTMPAQWIAQSGAQE
                     RSQRLCYLLKAESLMQWLDLNVLAELNGPEAKCPPLAMTVGLVPSLPAVDNNLWQLWI
                     TARTGLTPDIADTGTDDALPFPDALLRRLPRQSGFTPLRRACVTMLGVTTVAGIAALC
                     LSATANRQLLRQVGDDLHRFYAVPAEEFITKARHLSVLKDDAVMLDGYYREGEPLRLG
                     LGLYPGERIRQPVLRAIRDWRPPEQKMDVTASLPVQTVRLDSMSLFDVGQARLKDGST
                     KVLVDALVNIRAKPGWLILVAGYTDATGDEKSNQQLSLRRAEAVRNWMLQTSDIPATC
                     FAVQGLGESQPAATNDTPQGRAVNRRVEISLVPRSDACQDVK"
     gene            5931..6422
                     /locus_tag="LSX49_004689"
     CDS             5931..6422
                     /locus_tag="LSX49_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HBL7170979.1"
                     /translation="MAIPAYLWLKDDGGADIKGSVDVQGREGSIEVVALDHDVYIPTD
                     NNTGKLTGTRTHKPFTFTKEIDASSPYLYKAVTTGQTLKTAEFKFYRINDAGQEVEYF
                     NITLDNVKLVRVAPLMHDIKDPSREKHNHLERIEFRYEKITWTYKDGNIIHSDSWNER
                     PSA"
     gene            6613..9249
                     /gene="tssH"
                     /locus_tag="LSX49_004690"
     CDS             6613..9249
                     /gene="tssH"
                     /locus_tag="LSX49_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HBL7170980.1"
                     /translation="MTGNHPAALLRRLNPYCARALDAAASLCQTRAHAEITIEHWLLK
                     LLEQGEGDITVIARRYEWDIDTLWQSLLAHLDTLPRPVRERPQLSEPLAALIRQAWLI
                     ASLEGDDPQIRSQHLLMALTEKPMLPACNDLWVLLSLSRVQLERLRPLLDAQSDECPA
                     RQPQVTEPLTSAQPGAATTDAPAKTLTGKQDDALLAVLNRFTEDVTEKARSGRIDPVF
                     GRDTEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALRITEGNVPDSLKTVHIRT
                     LDLGLLQAGAGVKGEFEQRLKNVIDAVQKSPEPVLLFIDEAHTIIGAGNQAGGADAAN
                     LLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKA
                     RYAQHHGVHMLDSAIQTAVRLSRRYLTGRQLPDKAVDLLDTAGARVRMSLDTLPEPLT
                     QLHARLAALDIEREAIEQDSVFYPETSPERLAELTDLRDELQAEAGHLEAQYQQEKAL
                     AQQIMTLRQEGTDSSELQQQLRTHQGFAPLLALDVDARAVATVVADWTGIPLSSLLRD
                     EQSDLLSMEQSLENRVVGQSPALCAIAQRLRAAKTGLTPENGPQGVFLLTGPSGTGKT
                     ETALTLADTLFGGEKSLITINLSEYQEPHTVSQLKGSPPGYVGYGQGGVLTEAVRKRP
                     YSVVLLDEVEKAHRDVMNLFYQVFDRGFMRDGEGRVIDFRNTVILMTANLGSDHIMQL
                     LEEKPDATDADLHELLYPLLRDHFQPALMARFQTVIYRPLGQEAMRTIVEMKLAQVVR
                     RLHQHYGLETEINDSLYDQLTAACLLPDTGARNIDSLLNQQILPVLSQQLLAQQAVHH
                     KPARLRLGWDEEDGIVLEFDEK"
     gene            9261..>9711
                     /locus_tag="LSX49_004691"
     CDS             9261..>9711
                     /locus_tag="LSX49_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HBL7170981.1"
                     /translation="MNVQFFDHAHHKLKIRGLKSPVDVLTFTGHEQLSSPFRYDIEFT
                     STDKAIEPESVLMQDGAFSLSAPPVQGMPVQVPLRTLHGVITGFKHLSSSQDEARYEV
                     RLEPRMALLTRSRQNAIYQNQTVPQIVEKILRERHQMRGQDFVFNLKS"
BASE COUNT         2179 a         2727 c         2796 g         2009 t
ORIGIN      
        1 ctcatcattg ctttttattt aaatcatccg ataatcccct gaatataatt atgtcaataa
       61 ccatcagaaa aagtggatga tgaggaaaag gatatggccg acagtttcca gaatgaagtt
      121 cccgccgctc gtgtaaatat caagcttgac ctgcatacag gcaatgctaa aaagaaagtt
      181 gaactccccc tcaagcttct tgccgtaggc gattacagta acggaaaaga gcagcgtccg
      241 ctgtccgaac gggacaagat tgatatcaat aaaaacaact tcaacagcgt catggctgag
      301 ttttcgcctg cggttaattt aacagtagaa gatacgctaa acggaaacgg taatgaacaa
      361 aatatcgcgc ttgaatttaa aagcctgaag gattttgagc ccgaacaggt agcaaaaaat
      421 attccacaac ttcgtgtatt actcgctatg cgcaatttac tacgtgacct gaaatccaat
      481 ctgctggata acgcaacgtt tcgccgtgaa ctggaaaata tcctgaaaga cccgacgctc
      541 agttcagaac tgcgtgatga actggcgaaa attgcgccgc aggagaacgt ttaacccgaa
      601 cgcgtattca ggttaaaccg gagaagaaag gatcactgaa aaggaaatgc tgatgtctgt
      661 acaacaagaa catgccacct ctgaaactgc aacactcacc accactgagt ccggcggcgt
      721 ttatcagtcc ctgtttgata aaattaattt aaccccggtc tcttccattc aggaaatcga
      781 ttcatggcaa aacagcgaaa cgctggccga tgcctcaccc gatgagcgcg tgacggcggc
      841 tatccacgtt ctgctttcct gtctggcgaa gtctggcgag gacgtggtta aactcgacaa
      901 aagcctgctg gattttcata tcgacgatct ggatcagaaa atcagtaaac agcttgatgc
      961 agtcatgcac catccggaat tccagaaagt cgagtcgctc tggcgcggca catggttcgt
     1021 cgtacagcgc actgattttc gcaaaaatgt cagaattgaa ctgctggatg tcagtaaaga
     1081 acatctgcgg caggactttg atgattctcc ggaaatcatt caaagtggtt tatatcgcca
     1141 tacatacatt caggagtacg atacgccggg tggcgaacct gtagcctcat taatatccag
     1201 ctatgaattc gataacagcc cgcaggatat tgccctgctg cgtaatattt ccagagtctc
     1261 tgctgcatca catatgccct ttatcggttc cgtcggaccg aagttcttcc ttaaaaactc
     1321 gatggaagaa gtcgccgcaa ttaaagatat cggcaactat tttgaccgcg cggaatatat
     1381 caaatggaag tcgttccgcg ataccgacga cagtcgctac gtgggattag tgatgccgcg
     1441 cgtgctgggc cgtctgccct atgggccgga cacagtgccg gtacgcagct ttaactatgt
     1501 ggaagaagtc aaaggcccgg atcacgaaaa atacctctgg acaaacgcct cgttcgcctt
     1561 tgccgccaat atggtgaaga gctttgtgaa taatggctgg tgcgtgcaga tccgtggtcc
     1621 gcaggcgggt ggcgcagtgg ccgatctgcc gatccatctt tacgatctcg gcaccggcaa
     1681 tcaggtcaaa attccgtccg aagtgatgat cccggaaacc cgcgaatttg aatttgccaa
     1741 ccttggcttt attccgctct cttattataa gaatcgcgat tacgcctgct tcttctcagc
     1801 gaactctgcc cagaaaccgg cgttgtatga taccgctgac gccaccgcca acagtcgtat
     1861 taacgcccgt ttgccctata ttttcctgct gtcccgcatt gcgcattacc tgaaaatcat
     1921 ccagcgcgag aatatcggta ccaccaaaga ccgccgcgta ctggaactgg agcttaacac
     1981 ctggatccgc acactggtga cggagatgac cgatccgggt gatgaactgc aggcgtctca
     2041 cccgctgcgc gacggcaagg ttatcgtgga agatattgag gacaatccgg gcttcttccg
     2101 cgtcagactc tttgccgtgc cgcatttcca gattgaaggg atggatatca acctgtcact
     2161 ggtttcccag atgccgaaag cgaaagcctg accgggccgt ggtgtgatat gaaaattcat
     2221 cgaccactgt gggctgaggg gacattcctg tcctctcagc agtttcagca gcaggcccgc
     2281 tgggaagcgt tcagcaatga cagcattgcg caactttgta ttcgtcatcc gtgggggatc
     2341 gcgaatgtgc tctttgaccg cgatgccctg acgtccggaa agctgaaaac gcaggctgta
     2401 cgtctgcgtt ttgctgatgg cacgctgatc gattcagacg tgagtgacgt tctgccgctc
     2461 gcctgcgatc tgcgcgcgct gaagaacgac agcgcgattg tcctgctggc gctgccgctt
     2521 gcgcatggta acggcggtaa tctcggtcag ggtgagcaga ctgaaagacc gctgcgctat
     2581 cgtcaggaat ggcaaaaggt gcaggatatc tacggcagtg acagtgaaga tatggccgtt
     2641 gagcgtcatg cgctgtccct gcgctttgct catgataaca atcaggatta catcacctgc
     2701 ccactggcgc gtctggtgcg ggatgttcag ggcaactgga cacaggatga gagctatatt
     2761 ccgccgttac tggcgtttaa cgcccatgac gggctggtac agcgtctgga cacgctgctg
     2821 ttgcagctac gggcgaagtg ccagcgtctg atggcgatgc gccgggaaag caaccagcgt
     2881 atggcggact tcgctgtcgc cgatgtctcc ctgttctggc tgcttaacgc gctgaactcc
     2941 gccgagccgg tactgagtga tttcctgcgc tacccggcgg ttcatcccga actggtctgg
     3001 cgggagctgg cgaggcttgc cggtgcgctg ctgacgtttt cccttgaaca taacgtcagc
     3061 gccgttccgc cctatgtcca cgaatcgccg tccatcgtct ttccgccact tttctccctg
     3121 ctcagcgaac tgctggaagc cagcctgccg tcacgggtga tcgcgctgga tctggcgtcc
     3181 ctgccgggca accgctggaa agcagacctg cacgatccgc gcctgcggga agaggccgac
     3241 ttttacctgt ccgttcgttc ctctctgcct gcgcatcagg tactgcacca gctaccgctg
     3301 gtctgcaaaa tcggtgcgcc tgatgacgtc acgctgctta tcaatgtggc gctgaatggt
     3361 gttccactgg tgccgcttac ctcagttccg gcagcgctgc cactgcggct ggagaaccag
     3421 tattttgcgc tggatatgca cagtgacgcg gctaaatcga tgctggagtc cgggtgctgc
     3481 atgatttatg cgccgggaac aatgggcgac ctgaaacctg aactgtttgc ggtgctgcgc
     3541 acatgaaaaa agagacggat atcaatatcg acgcgctgct gcgcgacacg tttctgacgg
     3601 tggtggaact gcgtcaggga accaccgtgc gtcacggtat ggagctgtat cgccactgcc
     3661 agcggcaggt ggaactggtc cgcgaacgcc tgaaagatgc cgggttcagc cgggagagcg
     3721 tggagcacat tacttacgcg cagtgcgccc tgctggacga aacggtcctg agccgtggcg
     3781 gcatggacga cggtcaggcc atctggatga aggatccact ccagtcgcat ttcttcaaca
     3841 ctctgcaggc cggtgagctg ctgtacgagc ggatgaagca ggtgctacag gagcccgccc
     3901 ccgcgcaggc cgtgctgacc tgctttcacc gtgtcctgct gctgggattt cgcgggcgtt
     3961 atcaggatcc ggcagccccg gagcgcgacc agcttatttc gacgctcaac gggcaggtcg
     4021 cgccatttgg tgtgctgccg gaaacggcgg tactgaacgt gccgttatcc ccccgtcagc
     4081 accctttgct gcattcgccg tttttctggc tggtgacgct cacactggta ctggccggtg
     4141 tctggtgggg gctacattac tggctgaacg tgctggtgga tgaactgctg ccgcaaagtc
     4201 tgcgttaaag ggagtcgtga gtgaggaatg cgctgaaaca gacggttttg ttatggactc
     4261 tgttgttgct gctgactacc tggctgggtt tctttgctgt atctgcggtc gtgaagtatg
     4321 ccgtggtagt gattcttgtc gccgtcacag cggcggtgat ggcgtactgg cataagaaaa
     4381 agggacaggt cgtagcggac gacgtatggc cgtcatcgct accgccggaa acctaccgac
     4441 agccggtagt gctggtctgt ggcgatatgt cggcgcacct gttcactgac agcccggtcc
     4501 ggcaggtttc agaagggctg tatctgcctg tttctgatga agaacagctt gtggcgcagg
     4561 tggagcgatt actgaccctt cgcccggcgt gggcatcgca gtttgccgtg gcgtataccg
     4621 tcatgcccgg catgtaccgg gatgcggcgg ttctgaccgg acaactgcgc cggttcgctc
     4681 acagtatggc gacggtgcgt cgccgggcgg gcgtaaacgt accctggctt ctctggagcg
     4741 ggctgtccgg ctcgccgttg ccggagagag cgaattcacc gtggtttatc tgtaccggcg
     4801 gcgaagttca ggtagcaaca tccgcagaga ccaccatgcc cgcgcagtgg attgcacaat
     4861 ccggcgcaca ggaacgcagt cagcgactct gttacctgct gaaagccgaa agcctgatgc
     4921 agtggctgga tctgaatgtg ctggcggaac tgaacggccc ggaggcgaaa tgtccaccac
     4981 tggcgatgac cgttgggctg gtcccctcgt tgcctgcggt ggataacaac ctgtggcagt
     5041 tgtggatcac cgccagaacc ggcctgacgc cggatatcgc ggacaccggc acagacgatg
     5101 cgctgccatt cccggatgcc ctgttacggc ggttgccgcg tcagtcgggc tttaccccgc
     5161 tgcgacgggc ctgcgtgacc atgctgggcg tcaccaccgt ggcgggtatc gccgcgctgt
     5221 gcctgtcagc cacggcaaat cgccagttat tacggcaggt cggtgacgat ctgcaccggt
     5281 tttatgccgt cccggcggaa gaatttatca ccaaagcccg tcacctgtcg gtgctgaaag
     5341 acgatgcggt catgctcgat gggtattacc gggaaggaga accactacgt ctcggtctgg
     5401 ggttataccc cggtgaacgc atccgccagc cggtattacg cgccattcgc gactggcgtc
     5461 cgcctgagca aaaaatggac gtgacggctt cgcttccggt tcagaccgtg cgtcttgaca
     5521 gtatgtcgct gtttgacgtc ggacaggccc gcctgaaaga cggctcgaca aaagtgctgg
     5581 tggatgcgct ggtgaacatc cgggcaaaac cgggctggct gatcctcgtg gccggatata
     5641 ccgatgccac cggcgatgaa aaaagcaatc agcagttatc gctgcggcgt gccgaagcgg
     5701 tgcgcaactg gatgctgcag accagcgaca tcccggccac ctgttttgcc gtacagggac
     5761 tgggcgagag ccagcctgcg gcgaccaacg acacgccaca gggccgggca gtcaaccggc
     5821 gtgtcgaaat cagtcttgtt ccgcgttctg acgcctgtca ggacgtgaaa taaaacatac
     5881 cgccggaaga aggcggtgct tcaatcacac taacaaggag agtaattctc atggctattc
     5941 ctgcttatct ctggctgaaa gatgacggcg gcgcggatat caaaggttcc gtggacgttc
     6001 aggggcgcga aggtagcatc gaagtggtgg cgctggatca cgatgtgtac atcccgaccg
     6061 acaacaacac cggcaaactg accggtaccc gtactcacaa gccctttacg tttaccaaag
     6121 aaatcgatgc ctccagcccg tatctctaca aagctgtgac caccggccag actctgaaaa
     6181 cggcagaatt taagttttac cgcatcaacg atgccggtca ggaagtggag tacttcaaca
     6241 tcacgcttga taacgtcaag ctggtcagag tcgctccgct tatgcacgac atcaaggatc
     6301 cttccagaga gaagcataac cacctggaac gtattgagtt ccgctacgag aaaatcacct
     6361 ggacttacaa agacggcaac atcattcatt ccgactcgtg gaatgagcgt ccttccgcct
     6421 gataactgcg gcagacagga aactgtctgc ctttttgttg tgtgctttgt ccagtgccgc
     6481 aggcaccggt actgagcaaa gcatacccac aatctggtga aacctgatgg gcctgagtga
     6541 ggtaacggct atgggcggta gcgtgcctga acgcggatcg caggaataca gaacacgata
     6601 aggaaacctt ctatgaccgg aaatcacccc gccgcgctgc tgcgtcgcct taacccatac
     6661 tgtgcacggg cgctggacgc tgccgcctca ctgtgtcaga cccgcgccca tgcggaaata
     6721 accattgaac actggctgct gaaactgctg gagcagggag aaggcgatat cacggtgatt
     6781 gcccgccgct atgaatggga tatcgacacg ctctggcagt ctctgctggc acatctggac
     6841 accttacccc gcccggtccg cgaacgtcct caactttctg aaccgctggc agcgcttatc
     6901 cgacaggcgt ggctgatagc gtcactggaa ggcgacgatc cacaaatccg cagccagcat
     6961 ctgctgatgg cgctgacaga aaaaccgatg ctgcccgcct gtaatgacct gtgggtattg
     7021 ctgagcctga gccgtgtgca gcttgagcgg ctgcgtcccc tgctggatgc gcagtcggat
     7081 gaatgtccgg cacgtcagcc acaggtcacc gaaccgctga catccgcgca acccggggcg
     7141 gcaacgacgg acgcaccggc aaaaacgctg acggggaaac aggatgacgc cctgctggcg
     7201 gtgcttaacc gctttaccga agacgtgacg gaaaaagccc gcagcgggcg aatcgacccg
     7261 gtattcgggc gcgacacgga aattcgccag atggtcgata tcctctcccg tcgccgcaaa
     7321 aacaacccga ttctggtggg agaaccgggg gtgggcaaaa ccgcgctggt ggaagggctg
     7381 gcgctgcgta tcaccgaagg caacgtgccg gacagcctga aaacggtgca tatccgcaca
     7441 ctggacctcg gtctgttaca ggctggcgcg ggcgttaaag gtgaatttga acagcggctg
     7501 aaaaatgtca tcgatgcagt gcagaaatca ccggaaccgg tactgctgtt tattgatgaa
     7561 gcccatacca ttatcggtgc gggtaatcag gcaggcggcg cggatgcggc gaacctgctg
     7621 aaaccggcgc tggcaagggg cgaactgcgc accatcgcgg cgaccacgtg gagcgaatac
     7681 aaacagtatt ttgagcgcga cgccgcgctg gaacgccgct tccagatggt gaaagtcgac
     7741 gagccggatg atgacaccgc ctgcctgatg ctgcggggac tcaaggcccg ctatgcacag
     7801 caccacggcg tacatatgct ggacagcgcc attcagaccg ccgtgcgcct gtcgcgccgc
     7861 tatctgaccg gacgccagtt gccggacaaa gcggttgatt tgctggatac cgccggggca
     7921 agagtccgca tgagccttga cactctgccg gagccgttga cgcagcttca tgcgcgactg
     7981 gcggcgctgg atatcgagcg ggaggcgatt gagcaggaca gcgtgtttta tcccgaaacc
     8041 agcccggagc ggctggcgga actgaccgat ttgcgtgatg agctacaggc agaagccggg
     8101 catctggaag cgcagtatca gcaggaaaag gcactggcgc agcagattat gacgttgcgt
     8161 caggaaggaa cagacagctc tgaactgcaa cagcaactgc ggacgcatca gggctttgca
     8221 ccgctgctgg cgctggatgt ggacgcccgc gccgtcgcca cggtggtggc ggactggacc
     8281 ggcatcccgc tctcttccct gctcagggac gagcagagcg acctgctcag tatggaacag
     8341 agtcttgaaa accgcgttgt cgggcaaagc ccggcgctct gcgccatcgc acagcggctg
     8401 cgggcggcta aaaccggcct cacgccggag aacggcccac agggggtatt cctgctgacc
     8461 ggccccagcg gcaccggcaa aaccgaaact gcgctcacac tggccgacac cctgtttggt
     8521 ggtgaaaaat cccttatcac cattaatctt tcggaatacc aggaaccgca taccgtttcc
     8581 cagttgaaag gctcgcctcc aggctacgtt ggttacggtc agggtggcgt acttaccgaa
     8641 gccgttcgca aacgccctta cagcgtggtg ctgctcgacg aagtggaaaa ggcgcatcgc
     8701 gacgtgatga acctgttcta tcaggtgttc gaccggggct ttatgcgcga cggcgaaggg
     8761 cgggtaatcg acttccgcaa caccgtcatt ctgatgaccg ccaatctggg cagcgaccac
     8821 atcatgcaac tgctggagga aaaaccggac gccacggacg cagacctgca tgaactgctg
     8881 tatccccttc tgcgagacca ttttcagcct gcactgatgg cgcgttttca gacggtgatt
     8941 taccgcccgc tgggacagga ggcgatgcgc accattgtgg aaatgaaact ggcgcaggtg
     9001 gtccgccgtc ttcaccagca ctacggactg gaaacggaaa tcaacgacag cctgtatgac
     9061 cagcttaccg ccgcctgcct gctgccggat accggggcgc gcaatatcga cagcctcctg
     9121 aaccagcaaa tcctgccggt cttaagccag cagttgctgg cacagcaggc cgtgcatcat
     9181 aagcctgccc gactgcggct tggctgggat gaggaggacg ggattgtact ggaatttgat
     9241 gagaaataat ggaggctctt atgaacgtac agttcttcga ccacgcacac cacaagctca
     9301 aaattcgcgg cctgaaaagc ccggtggacg tgctgacttt tacaggccac gaacagctca
     9361 gctcaccctt ccgctacgac attgagttta ccagtaccga taaagccatc gagccggagt
     9421 cggtactgat gcaggacggc gcattcagcc tgagcgcccc gccggtacag gggatgccgg
     9481 tgcaggtccc cctgcgcacc ctgcacggcg tcattaccgg ctttaaacac ctctcctcgt
     9541 cacaggacga agcccgttac gaagtgcgcc ttgaaccccg tatggcgctg cttacccgca
     9601 gccgccagaa cgccatctac cagaaccaga cggtgccgca aatcgtcgaa aaaatcctgc
     9661 gcgagcggca ccagatgcgc ggtcaggact tcgtgtttaa cctcaaaagc g
//
LOCUS       DAFGPF010000164         9687 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFGPF010000164 DAFGPF010000000
VERSION     DAFGPF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9687
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.164"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            44..535
                     /locus_tag="LSX49_004692"
     CDS             44..535
                     /locus_tag="LSX49_004692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL7170982.1"
                     /translation="MGKKTAPLLPYTNQMLSEFGERLKLARLRRRLTAKQVAERAGMS
                     PITLRSLESGSAGVTIGAYLSVMQVLGLETDLNKLAAEDDLGRQLQDSRLIKKRGLSR
                     VSSKNEEGSQTASLQMRHEKEGHLTTDLTALAEGSTPSITGETSTSLAALLKPIKKPL
                     KGN"
     gene            538..1805
                     /locus_tag="LSX49_004693"
                     /pseudo
     CDS             538..1805
                     /locus_tag="LSX49_004693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606689.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HipA domain-containing protein"
     gene            complement(1948..3225)
                     /locus_tag="LSX49_004694"
     CDS             complement(1948..3225)
                     /locus_tag="LSX49_004694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7170983.1"
                     /translation="MNKIKNYRWHMIALVCFITVINYLDRTALGIAAPTIMETTGITK
                     EQYSWIVSAFQLAYTLGQPIMGFFIDTVGLKLSFAICAAIWGLATMGHALTGTWSGLA
                     FMRALMGFSEASAIPAGVKTASTWFPAKERGVATGVFNMGTSLGAMLAPPLIAWCIMF
                     HSWQFAFIVSGSLALLAALFWFFCYKDPKDAKRLSDEERHYIESGQEQHLKTDKKEKT
                     SIKHILSQRNFWGIGIARFLADPAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLLG
                     DLGCLASGFVAKFFHDRGVSLINSRRITFTIAAVIMMTIGLVSIVENPYIAVLLISIG
                     AFSHQCLSTVAATLGGDLFKKDEVATAVGMAGACAWSGQLIFNLFIGAFVHIIGFAPF
                     FIALAFFDIIGAIALWTLIKVKDEEPQVQLATS"
     gene            complement(3318..5390)
                     /locus_tag="LSX49_004695"
     CDS             complement(3318..5390)
                     /locus_tag="LSX49_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBL7170984.1"
                     /translation="MSQLDDTILDALTHVTFPKGFAQAEPAWVVTVDGVDYPLWKTDA
                     LVVGSGAAGLRAAVELKRRQQNVLIATAGLYMGTSACSGSDKQTLFTAATAGNGDNFT
                     KLAEALASGGAMDHDTAYVEAVGSLHTLGGLQYLGLELPEDRYGAILRYQTDHDEAGR
                     ATSCGPRTSRLMVKVLLEEVQRLAIPMLTSATVIKLLHQRDENGEDRVAGAILATGHR
                     AHNPWGLAIVTAPNVVLATGGPGELYRDSVYPHKCFGSLGLALEEGLTLTNLTESQFG
                     IGTPRSTFPWNLSGTYVQVIPYIYSVDAEGNEYNFLADYYRTTQELASNIFRKGYQWP
                     FHATRVMDFGSSLLDMAVAQEQQSGRQVFMDFNRNPEAVPGDLPFSLDRLDDDVRTYL
                     ENNDALAPSPIERLQRMNPLSISLYKMHGYDLTTQPLQFAMNNQHMNGGIEVDIWGQT
                     SLPGCFAVGEVAGTHGVTRPGGAALNAGQVFAVRLARFIGCTQKRNIDGDIAQLAAPA
                     LASIREIITQAHDNGTGMPLSVVREKIQARMSDHAGFICHADKVRRATRDALLLNEFV
                     QRHGLAIKHVGEVAELFMWRHMTLTSAAVLTQLTHYIDAGGGSRGARMVIDPQGKCLP
                     QTRRGAKEEWRFRSELAEDKNHKLTIQYSQGSFITEVKSLRMQPCINGIYFEKNWPDF
                     LKGDIYTQ"
     gene            complement(5387..6928)
                     /locus_tag="LSX49_004696"
     CDS             complement(5387..6928)
                     /locus_tag="LSX49_004696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HBL7170985.1"
                     /translation="MRKLSTAETLAAQIQDGATIAISGNGGGMVEADHILAAIEARFL
                     QTGHPRDLTLIHSLGIGDRDSKGTNRFAHAEMLKRIIAGHFTWSPKMQELVKNNAIEA
                     YCFPGGVIQALLREIGAGRPGLFTHVGLGSFVDPRNGGGKSNECTTDDLVELIEIDGE
                     TKLRYRPFKVDYAILRGTYADPRGNVSLEEEAIDMDSYSMALAAHNSGGKVFVQVRDV
                     LEAGTIEPRRVKLPGILVDGIVEHREQPQTYLGGYDLTISGQHRRLSSNDAIELVSHP
                     VRRLIARRAARELVAGASTNFGFGIPGGIPGVALREGVPYQSLWLSVEQGVHNGMMLD
                     DALFGCARNADAIIPSLDQFEFYSGGGIDITFLGMGEMDQYGNVNVSHLNGNLIGPGG
                     FLEIAQNARKVVFCGTFDAKGSKIDVTPDGLHIAQSGQIPKLVTQVEKITFSAAYAQQ
                     SGQEVLYITERAVFQLTAEGVELIEIAPGVEIERDILPYMAFRPIIRHPRLMESSLFM
                     PMEDA"
     gene            complement(6938..7714)
                     /locus_tag="LSX49_004697"
     CDS             complement(6938..7714)
                     /locus_tag="LSX49_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBL7170986.1"
                     /translation="MNDQPVLFSRAAASCRLTLNREDKCHAINEEMIESLDHYLNEIE
                     NDTALRLVELTATGDKFFCAGGDIKSWSAYSPLDMGRKWIKRGNDVFNRLRNLPQLTV
                     ANLNGHTIGGGIELALCCDIRIARPGAKFSNPEVMLGMVPGWMGIERVLNQVGPVVGR
                     QMLMLGKRLTAQEAQTANLIDEVVEKEQVESWMANQLAQLEKCGPVALAHIKQLILAL
                     ENKHADYSHQLLAGLMSATQDCQQATHAFAEKAGVSFHNQ"
     gene            complement(7724..8566)
                     /locus_tag="LSX49_004698"
     CDS             complement(7724..8566)
                     /locus_tag="LSX49_004698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL7170987.1"
                     /translation="MRDLLQRPDLFSINTATLGYKTPLPAIIDACAARGIGAIAPWRR
                     ELQSEDLQQTARQLAASNMNVSGLCRSTYYTAPTLAERKLAIDDNRRALDDAAVLNAA
                     CYMQVVGGLPMGTKDLYEAREQVKQGIRQLLPHSKEVGVPIALEPLHPMTAANRSCLC
                     TLRQALDWCDELDPDGEFGLGVAVDVYHVWWDPDLASQILRAGKRILAFHVSDWLVPT
                     TDLVNDRGMPGDGVINIPSIRRLVENAGFNGAIELEIFSPYWWQKDINSTLDISVDRI
                     AHYC"
     gene            complement(8576..9367)
                     /locus_tag="LSX49_004699"
     CDS             complement(8576..9367)
                     /locus_tag="LSX49_004699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="HBL7170988.1"
                     /translation="MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVE
                     KLHATQQECLAEGVEVICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRG
                     DLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
                     AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAK
                     GLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLSMPRF"
     gene            9580..>9687
                     /locus_tag="LSX49_004700"
     CDS             9580..>9687
                     /locus_tag="LSX49_004700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7170989.1"
                     /translation="MYLDTSNVQSLKEKLLLCAVNEFAEYGYEGARVDNI"
BASE COUNT         2487 a         2381 c         2372 g         2447 t
ORIGIN      
        1 tattatggct atcatagcca taaaaagata aaatattatc actatgggta aaaaaacagc
       61 accgttactc ccttatacga atcagatgct tagtgaattt ggtgagcggc tgaaacttgc
      121 tcgtttacga cgcaggctta ccgcaaagca agttgctgaa cgtgctggga tgtcgccaat
      181 aacattgcgc tctctggagt caggaagtgc aggggtcacg ataggggcat atttgtctgt
      241 gatgcaggtt ttgggcctgg aaacggattt aaataagctt gcagctgaag acgacttagg
      301 gcgtcagctc caggattccc gtttgattaa aaaaagaggg ctgtctcgtg tatcaagtaa
      361 gaatgaagaa ggttctcaga cagcctcatt gcagatgagg cacgagaaag aaggtcatct
      421 caccacggat ttaacagcac tggcagaagg ctcgacgcca tctattacag gagaaacatc
      481 aacctctctt gctgcactat taaaaccgat aaaaaaaccg ttaaaaggaa attaattatg
      541 gcattaatcg gagtgtatgc ggattgggaa ggcctggatg gtcctgcgcg tattggttat
      601 ttacacagtc gtcgcactcg ggcgcgtgag atatttgagt ttgagtacga taaaaaggcg
      661 cttgcagatc cttcacttaa tttcattcag ttagatcctg aaataatgtt gtatgaggga
      721 gcacagtacc caattcctcc aaaggataaa tttggtgcat ttagtgattc ctgcccggat
      781 cgttgggggc gtatgctaat gaagcgtcgt tttgagaggg atattcgaga cgggttatgt
      841 gataaagact cccaccttta tgagtctgat tatctactag gtgttcatga tctttatcgg
      901 gttggggctc ttcgatacaa acgtgaagac gctggagagt ttcttgataa tcgcattgat
      961 gttgcagccc caccatttac cgaaatagcg agtctggaaa gggttagccg ggcaattgaa
     1021 gaagatcctg ataataaaga gtaatggggc aaaaatggtt aagaatgcta atcgctccgg
     1081 ggggatcatt agggggggca cgtccgaaag ccagtgttgt tgatgaagct gggcatctct
     1141 acatcgctaa atttcccagt gtaaaagatg agtatgatgt tggtggatgg gaaatggtcg
     1201 ttaatgcact tgctgttggc tgtggactga atgttgcacc tgctcaggcg cataaatttg
     1261 ccagcaatta ccattgtttt atggttcgtc gttttgaccg cactaatgcg ggaaggcgtc
     1321 tgcattttgc ttcggctatg acactaacca ggcatcagga tggtgaagat gcctctacag
     1381 gtgtgagtta tctggaatta gcagatgttc ttatcagaca tggcgcgcag actaatactg
     1441 accttaagga actctggtcc aggattgttt ttaatattct tgttactaat accgatgatc
     1501 atttacgcaa tcatggattt atcttgatac caggaaaagg ttggcggctt tctgaggcat
     1561 atgatttgaa tcctgtggtc aggtctgatg gtctaaaact caatattacg gaaaatgaca
     1621 atgcacttga tttggaatta gctagagaag ttgcagagta ttttcgactt agtttgacgg
     1681 aagctgatga cattattgct aattttagag ggattgtcag tcagtggcga atcattgccg
     1741 agcgtcttcg attacctggt cgtgagcaag agttaatggc agaggcgttc aggggggcaa
     1801 tttagaatag ttatttcgat atattcgcta aatcataaat ttgcgaagca atgccagtag
     1861 atactgaacg ttttggaaga gacgtttaat ttatgagaaa aatagaaacg ctacaaagct
     1921 aaattatagc gtttctatgt aaaataatta gcttgtcgct aactgtactt gtggttcttc
     1981 gtctttaact ttgataagcg tccacagcgc aatggcgcca ataatgtcaa agaaagccag
     2041 ggcaataaag aacggcgcga agccgataat gtgaacgaat gccccgataa acaggttgaa
     2101 aatcaactga ccgctccatg cacaggctcc tgccataccc acagcggtag ctacttcgtc
     2161 ttttttgaat aggtcaccgc ccagagttgc tgcaacagta gaaagacatt gatgcgagaa
     2221 tgcgccaatg ctaatcagta atacggcgat gtagggattt tcgacaatac tcaccagacc
     2281 aatcgtcatc ataatgacgg ctgcaatagt gaaggtaatt cttcgtgagt taattaaact
     2341 cacgccgcga tcgtggaaga acttcgcgac aaaaccactg gctaaacagc cgagatcgcc
     2401 cagcaggaaa ggtagccaga cgaacatggc aatttctttc aggctaaaat gcagcgtttc
     2461 gacgaagaaa atcggtaccc agaagttaat ggttccccat gccgggtcag cgagaaaacg
     2521 cgcgatgcca atcccccaga aattacgttg gctgaggata tgcttgattg acgttttttc
     2581 tttcttatct gttttaagat gctgttcttg cccagactca atatagtggc gctcttcatc
     2641 agaaaggcgt ttagcatctt ttggatcttt ataacaaaag aaccaaaata aagccgcgag
     2701 taaagcaagg ctacctgaga caataaacgc aaattgccag ctatgaaaca taatgcacca
     2761 ggcaatcaac ggtggagcaa gcatcgcgcc gagtgaggtg cccatattga aaacacctgt
     2821 cgccacgcca cgctcttttg ccgggaacca tgttgatgcg gtttttacac ccgcaggaat
     2881 tgccgatgct tcgctgaaac ccatcagggc gcgcataaat gccagacctg accatgttcc
     2941 tgtcaaggca tgccccattg tcgccaggcc ccagattgcg gcacatatcg caaaacttaa
     3001 cttcagaccc acggtatcaa taaagaagcc cattatcggt tgccccaatg tataggccaa
     3061 ctggaatgca ctgacaatcc atgaatattg ttctttggtt attccggttg tctccataat
     3121 cgttggagcc gcaataccta acgccgttct gtccagataa ttgattacag tgataaagca
     3181 tacgagggca atcatatgcc atcgataatt ctttatttta ttcattttta aaccttttaa
     3241 ttatattaat aaaccctggt tgttggtatt tccatgtaat aggcaataaa aatcaggtac
     3301 agaggaaata ttggaaatta ttgtgtgtaa atgtctccct ttaaaaagtc tggccagttt
     3361 ttttcaaagt aaataccgtt aatacacggt tgcatacgta aagactttac ttcggtaata
     3421 aaagaacctt gcgaatattg aattgttaat ttgtgatttt tgtcttcagc gagttcagag
     3481 cgaaaacgcc attcttcttt tgcgccgcga cgagtttgtg gtaggcattt gccttgtgga
     3541 tcaataacca tacgcgcccc acggctacca ccaccagcat caatataatg cgttaattgt
     3601 gttaataccg cggcagaagt cagcgtcata tgccgccaca taaacagctc ggcaacttca
     3661 cccacatgtt tgattgccaa tccatgtcgt tggacaaatt cgttcaatag cagggcatca
     3721 cgagtggcgc gtcggacttt atcggcatgg caaataaatc ccgcatggtc agacattcgt
     3781 gcctgaattt tttctctcac aaccgacaac ggcatcccgg tcccgttatc gtgcgcctga
     3841 gtaatgatct ctcttataga agccagtgcc ggagctgcca gctgtgctat atctccatca
     3901 atattccgct tttgcgtgca accaataaaa cgtgccagac gaacagcaaa aacctgcccg
     3961 gcattcaatg ccgcgccgcc aggtcgggtg acgccgtgtg tgccagcaac ttcccccacc
     4021 gcaaaacaac cgggcagaga tgtttgtccc cagatatcga cttcaatgcc gccattcatg
     4081 tgctgattat tcatggcaaa ctgcaatggc tgcgtggtga gatcgtaacc gtgcatctta
     4141 tacagcgaga tagacagcgg attcattcgt tgcaggcgtt cgatgggcga tggtgccaga
     4201 gcgtcgttat tttccagata cgtgcgaacg tcgtcgtcca gtcgatctaa tgagaagggc
     4261 aggtcacccg gcaccgcttc aggattgcga ttgaaatcca taaatacctg acgccctgat
     4321 tgctgctctt gcgctactgc catatctaac aagctggagc caaaatccat tacccgcgtg
     4381 gcgtggaacg gccactgata gcctttacgg aagatgtttg aagctagctc ctgggtggtg
     4441 cgatagtaat ccgcgaggaa gttatactcg ttaccctcag catctacgga atagatatac
     4501 gggatcacct gcacataggt gccggacaaa ttccacggaa acgtgctgcg cggtgtgccg
     4561 ataccaaact ggctttcagt cagattggtt agcgtcagac cttcctccag cgccagaccc
     4621 agcgagccga aacatttgtg tggataaaca ctgtcgcgat aaagctcgcc aggccctcct
     4681 gttgccagta ccacattggg cgcagtcaca attgccagcc cccatgggtt atgggcgcga
     4741 tgaccggtcg cgaggattgc ccccgccaca cggtcttcac cgttttcgtc acgctgatgc
     4801 agcagtttaa tcactgttgc actggtcaac attgggatag caagacgctg tacttcttcc
     4861 agcagcactt tcaccattaa ccttgaggta cgcggcccac acgaggttgc acgcccggct
     4921 tcgtcatggt cggtttgata acgaagaatc gcgccatagc gatcttccgg taattccaga
     4981 ccaagatatt gcaacccgcc aagagtgtgc agagaaccta ccgcttcaac ataagcggtg
     5041 tcgtgatcca tcgccccacc gctcgccagt gcctctgcca gtttggtgaa gttgtcgccg
     5101 ttgcccgcag tagcggcggt aaacagtgtt tgtttatcag agccagaaca tgccgacgtc
     5161 cccatatata acccggcggt ggcgattaac acattttgct ggcggcgttt aagttccaca
     5221 gctgcacgta gcccggctgc accactgccg actaccaggg catctgtttt ccagagtggg
     5281 taatcaacgc cgtcaaccgt gacaacccat gcgggttctg cctgtgcaaa accctttggg
     5341 aaagtaacgt gcgtcagtgc atcaaggatg gtgtcatcaa gctgactcat gcatcctcca
     5401 ttggcataaa caggctactt tccatcagac gtgggtgcct gataatcgga cggaaggcca
     5461 tatacggcag aatgtcgcgc tcaatctcca cacccggcgc gatttcaatt aattcaacgc
     5521 cttctgccgt taactggaat actgcgcgtt cagtgatata caacacttcc tgaccacttt
     5581 gctgtgcgta ggcggcgcta aaagtaattt tttccacctg ggtaaccagt ttagggattt
     5641 gacctgactg ggcgatatgc aagccatctg gcgttacatc aatcttgctg cctttggcgt
     5701 cgaacgtacc gcaaaacacc actttacggg cgttttgtgc aatttcgaga aatccgccgg
     5761 ggccaatcag attgccattg agatgggata cgttgacgtt accgtattga tccatctctc
     5821 ccatgccgag gaaggtgata tcgatgccgc cgccactgta gaattcaaat tgatcgagtg
     5881 atggaataat ggcatcggcg ttacgggcgc agccgaacag agcatcatca agcatcatgc
     5941 cgttatgcac accctgttct acactcagcc acaaactttg ataaggcacg ccttcgcgca
     6001 gcgcaacccc aggaataccg ccgggaatac caaagccaaa gttggttgaa gcgcctgcca
     6061 ccagttcccg cgctgcccga cgggcaatca ggcgacgcac cggatgacta accagttcaa
     6121 tagcgtcgtt agaacttaga cggcgatgtt gaccgctgat ggtcaggtcg taaccaccaa
     6181 gataggtttg cggttgttcg cggtgctcaa cgatgccatc aaccagaatt cctggtagct
     6241 tgacccgacg tggttcaatg gtacctgctt ccagcacatc gcgtacctgt acgaacactt
     6301 tgccgccgct gttgtgtgct gccagcgcca tcgaatagct atccatatca atcgcttctt
     6361 cttcgaggct aacgttgcct cgtggatcgg cataagtgcc acgcaaaatc gcgtaatcca
     6421 ctttgaaagg gcgataacga agtttggtct caccgtcgat ttcaatcagt tctaccaggt
     6481 cgtcggtagt gcattcattc gacttaccgc caccattgcg tggatcaaca aacgatccca
     6541 gcccaacgtg ggtaaaaagc cccggacgtc cggcaccgat ctcccgcagc agtgcctgaa
     6601 ttacgccacc agggaaacag taggcttcaa tagcattgtt tttcaccagt tcctgcatct
     6661 tgggcgacca ggtaaaatgt ccggcaataa tgcgtttgag catttcggcg tgagcaaaac
     6721 ggttagtgcc tttgctgtcg cgatcgccaa tacccagcga gtggattaat gtcagatcgc
     6781 gcgggtgtcc ggtttgcaga aagcgcgctt caatggcggc cagaatatgg tcagcttcca
     6841 ccatgccgcc gccgttgccg ctaatggcaa tggttgcgcc gtcctgaatt tgcgccgcca
     6901 gtgtctcggc ggttgataac ttacgcatac aatttcctta ttgattgtgg aagctcacgc
     6961 cggctttttc ggcaaatgcg tgcgtcgcct gttggcaatc ctgagtggcg gacattaatc
     7021 cagccagcaa ctggtgcgag taatcggcgt gtttattttc cagcgccaga atcagttgct
     7081 taatatgtgc cagtgccacc ggaccacatt tttccagctg cgctaactgg ttcgccatcc
     7141 agctttccac ctgttctttt tctaccactt catcaattaa attcgctgtc tgagcttcct
     7201 gcgccgtcag gcgtttaccc agcatcagca tctggcgacc gaccacagga ccaacctgat
     7261 taagcactcg ctcaatgccc atccagcctg gcaccatgcc gagcatcact tccgggttag
     7321 agaatttcgc gccggggcga gcgatacgaa tatcgcagca caaggcaagt tcaataccac
     7381 cgccgatggt atgaccgttg agattcgcaa cggttaattg gggtaagttt cgcaggcgat
     7441 taaaaacgtc attaccgcgt ttaatccatt ttctgcccat atctaatggc gaataggccg
     7501 accacgattt aatatcgcca cccgcacaaa agaatttatc gccggttgcc gttaattcga
     7561 ctaagcgtaa tgccgtgtca ttttcaattt catttaaata atggtcgaga gattcgatca
     7621 tttcttcatt aatagcatga catttatctt cacggttcaa tgtcaggcgg caagaagccg
     7681 ccgctctgct gaacagaacg ggttggtcat tcatgatcat tccttaacaa taatgcgcga
     7741 tgcgatcgac gctaatatcc agcgtgctgt taatatcttt ctgccaccag tacggtgaga
     7801 atatttccag ttcaatagcg ccattaaatc cggcgttttc aaccagccga cgaattgacg
     7861 gaatattgat gacaccatct cccggcattc cacggtcatt gaccagatcg gtggtcggca
     7921 ctaaccagtc ggaaacatga aacgcgagga tgcgttttcc ggcacgcagg atctgactgg
     7981 cgagatccgg gtcccaccag acatggtaga catctaccgc cacgccgagg ccaaattcgc
     8041 catcgggatc gagttcatca caccagtcca gcgcctgacg taacgtgcac agacaagaac
     8101 gattggcagc agtcatcggg tgcagtggct ccagtgcaat tggcacgccg acctctttcg
     8161 aatgtggcag caactggcga atcccttgtt tcacctgttc ccgtgcttcg tacagatctt
     8221 ttgttcccat tggcagaccg ccaaccacct gcatataaca ggcggcgttc agtacagcgg
     8281 cgtcgtccag cgcccggcgg ttatcgtcaa tcgccagttt gcgctccgcc agcgtcggtg
     8341 cggtgtagta ggtgctacgg cacaaaccgg aaacgttcat gttactggca gcaagctggc
     8401 gggcggtttg ctggagatct tcactctgca actccctgcg ccagggggca atcgcgccaa
     8461 taccgcgtgc ggcgcaggca tcaataatgg cgggtagcgg cgttttatag cccagtgtcg
     8521 cggtattgat actgaataaa tccgggcgtt gtaacagatc tctcatgatt cagcctcaga
     8581 agcgcggcat acttaagccg ccgtcgatgg cgaccgcctg accacaggtg taaataagtt
     8641 taccttccgc catcgcgcgg acagtggaag caatatccgc cggataaccc caacgtcccc
     8701 acggcaccag acctttggca atcagttcgt cgtaataggc cgttgccgga atagtcatat
     8761 cggttttgat gagaccagga cgcacttcat atacgccaat ttgttcatta caaaggcgag
     8821 cagcaaacag acgagcagcg gcagagacgg cagttttggc aatggtatat tcgccgcgat
     8881 tcatcgccag catgatggcg ttgatggaac tgacaaaaat aatcgagcgg tgcggcagtt
     8941 ctgcttccgg tttcggctgt gccagtaagc gcttactgaa tgcctgagca aggaagaacg
     9001 gtgcgcgggt gttaatggca atattttggt cgaagctgtc tggttcgagg tcgagaaggt
     9061 caccgcgttt tttcactgaa atgcctgcgt tgttgagcag gcagtccaga cgtccccact
     9121 ggttttgcgc tgcgtcgagc atctcttcat gcagggagag atcgcccaca tcagcaggga
     9181 agcaaatcac ttccacgcct tccgccagac attcttgttg tgtggcatgt aatttttcta
     9241 cgctatccgc atccggacga tcattaatca gcagattaaa tccgccacgc gcaagctcca
     9301 gcgcacagcc ctttccaata ccacgagcgg ctccggtaat cacggcaaca ggacgagtgg
     9361 atttcataca atagctctct ttttttgaat tttgtttcct tagtgatgat tagcttgcga
     9421 ctggaggata aaaagatcaa ccatctagtt ggttgatatg cgatggcgat cacaggacat
     9481 ttgataacct gatgaaagta caagtttttg cccttttttc tgaagctgaa atcaaatcag
     9541 gttatgatag tcaccacgaa gaggtcgtgg ggaagcgtta tgtatcttga taccagcaac
     9601 gtacagagcc tgaaagaaaa gctgctgtta tgcgcggtta atgaatttgc cgaatatggt
     9661 tacgaagggg ccagagtcga taatatc
//
LOCUS       DAFGPF010000165         9590 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFGPF010000165 DAFGPF010000000
VERSION     DAFGPF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9590
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.165"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(55..336)
                     /locus_tag="LSX49_004701"
     CDS             complement(55..336)
                     /locus_tag="LSX49_004701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HBL7170990.1"
                     /translation="MNKYWLSGIIFLAYGLASPAFSSETATLTINGRISPPTCSMAMV
                     NGQPQQHCGQLTYNVDTRHQVSSPVKGVTTEVIAADSDSKRRIVLNRYD"
     gene            complement(599..1708)
                     /gene="apbC"
                     /locus_tag="LSX49_004702"
     CDS             complement(599..1708)
                     /gene="apbC"
                     /locus_tag="LSX49_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HBL7170991.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            1840..3873
                     /gene="metG"
                     /locus_tag="LSX49_004703"
     CDS             1840..3873
                     /gene="metG"
                     /locus_tag="LSX49_004703"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBL7170992.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAIREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            4014..7814
                     /locus_tag="LSX49_004704"
     CDS             4014..7814
                     /locus_tag="LSX49_004704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HBL7170993.1"
                     /translation="MRHFIYQDEKSHKFWAVEQQGNELHVSWGKVGTNGQNQVKSFAD
                     AAAAEKAKLKLIAEKTKKGYVENASANVHITPITKATPEVETSPESKNQRPWLADDAV
                     IRLTDDINRFAFPHRSRPREINYLHKDSQIWQRIANNTRAYDPANNYRSYPENWQQAF
                     AELQRRILDNQQTGSAQSDAALLWSFWNSYSADELVDDLIIRCGMESAVEIALLALQL
                     RYKPVKGAVTTIIPPNHEAESLPSWHQRLCHHLSLASEDEWQRCVDKVLAAITTLSPA
                     RQPFAALLLPERPDIANAMALRYADQNVPAMTWLRLVVTDEAALTAAEKYDFPPLYRD
                     FRAYLAMLLANNGVSGVSRILTEFVEEHSDNPTYLFERISETEDLVKWLWKTNHPDAI
                     QILILGVIGKKKHLEYLSKACQKHPAAAIAAYATLLAIHEDKEWHKALVKLITITPEL
                     VCDVIPWVSAKAAGILSECRPQSVAEECEYATADMLPELFVSPPWMTKEKKKNSPVFD
                     LPVLPVPSVSDVTPEIAKKLTRTYLVTRFQQIAQQQATKQILFTDLPLMEKASWERHL
                     VPLTPEQQILWCLGFDKWRESGEKIYEKIPAPQSAVDALLRFDFPALNAEFAQYHNNA
                     YKSWNLIALCYLPGQQAISFLNQIVKEDNYSGEGYILAIFGSAAIPAFMTCLQREPQR
                     LWFFTFFLGVNELALPMAQRLQKKMSYEDARNWLTDYPRHAAAGLLPVALGKQGKDRD
                     CARQALRLLVNLNQRETIEEIAQGYNQPDVLAALATLFDSEPLEEYPAKIAPLPGFYQ
                     FTLWRRPRLKSNNQPLPDDAMRHLGIMLSFPRDITPYAGLAIIKETFTRESLAEFGWD
                     LYTAWTEAGAPAKENWAFTSLGILGNDDTARKLTPLIRTWPGESQHKRAVYGLDVLAS
                     IGSDIALMLLNGIAKKIKFVALQEHACDKINMVAENRGLTMAELEDRLAPDLGLDSSG
                     SLTLDFGPRQFTVGFDETLKPVVRDANGKVLKDLPKPNQSDDKTLATDAVNLFKQLKK
                     DVRAIASQQIDRLEQAMCQRRRWTAEQFRLFLVEHPLVRHLTRRLLWGVYTEENTLIA
                     CFRVAEDSTYSDAQDELFTLPAGNIGIPHVLEISPESAAAFGQIYTDYEQLPPFRQLD
                     RGYYHLADNERDSHELIRWQGRLCQAGRIVGLERRGWQRLEESGSVYAMRKSTPYGDL
                     ELETEPFSLIYGETGYGDQLPVESVKITSPDNRYGKQSSLTFSALDDITASELINDIE
                     SLFD"
     gene            7827..8858
                     /locus_tag="LSX49_004705"
                     /pseudo
     CDS             7827..8858
                     /locus_tag="LSX49_004705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000860751.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="WGR domain-containing protein"
     gene            8942..9496
                     /locus_tag="LSX49_004706"
     CDS             8942..9496
                     /locus_tag="LSX49_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /protein_id="HBL7170994.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGRWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPYGPAVYMVQTRQAFERTRSDA"
BASE COUNT         2537 a         2432 c         2360 g         2261 t
ORIGIN      
        1 cattcatgta aatgatttaa gctttctaaa tccgattaaa accagggtgg caaattaatc
       61 gtagcgattt aacacgattc gacgtttgct atcgctatct gcagcaatca cttccgtcgt
      121 tacaccttta actggcgaag aaacctgatg acgggtatca acattatacg ttaactgacc
      181 acaatgctgt tgaggttgac cattaaccat agccatactg catgtcgggg gactgatcct
      241 accattaatc gttaatgtgg cagtttctga agagaacgcg ggagaagcca atccataggc
      301 aagaaaaata attcctgaca gccagtactt attcattgaa cgttatccct gtagtaaagg
      361 ttatgcctgg aaagaatgag tgcataacaa actatagctg tacatccact acacagccac
      421 gaaggatgat aatgaagcat cgccggtacg atcaatcgac tttgtagagt ttcggacgaa
      481 ggtccgcaga atattcgcaa cattaaataa gtgttcatta atgttgcaaa aacaaataca
      541 ccgcatcaat gtaacatctc tgcggtgtat gaagaataac cagaatggtt aatacgcgtt
      601 agaccgcgcg gaaggaaatc tcgccaggaa tgacttcacc ctgccagtag agctgagctg
      661 caacgcggtc agccagctgg cggtagatag cggtaaattc gctctcagga cggctgataa
      721 ccgttggcgt gcctttatcg agatcctcac gtaaggagat gtgtaacggc atctgcccca
      781 gcagctgcgt gtggtatttc tcggccagtt tctctgcacc accggtaccg aaaatcggct
      841 catggtgacc acagttactg caaatatgca cactcatgtt ctcgacaata ccgagcaccg
      901 gaacctcgac tttctcgaac atcacaatgc cttttttcgc atcgatcaac gcgatgtcct
      961 gcggggtggt gaccactacc gcgccagtta ctggaatgtt ttgtgccagt gtcaattgaa
     1021 tgtcaccggt acctggcggc atatcaagca ccagatagtc gagatccggc cacaaggttt
     1081 cctgcaacat ttgcattaac gccttgctcg ccattgggcc acgccacacc atcgcattgt
     1141 cgtcagtgac cagataacca attgaattgg ttgccaggcc atgagacata atcggtgcca
     1201 tatgggtacc gtccggcgaa gttggacgct gattttctgc gcccagcatg gtagggattg
     1261 atgggccgta gatatcggcg tccagaatgc cgactttcgc cccttctgcc gccagtgcca
     1321 acgccaggtt taccgccgtg gaggatttac ccacgccacc tttaccggaa ctgaccgcga
     1381 taatgttctt cacgccgtta attcccggct gattcttcac gcgtttcaga gtggctatgt
     1441 tatgcgacag tttccagtcg atagctttcg ctccggtgat gcgcagcagt tcggcgctac
     1501 attgctcttt taactcttcg aacgcgctat gccagacgaa tggcatgacc agttccacat
     1561 gcagcgtgtc gtccatccag gcgacatggt gcaacgcttt cagcgttgtg aggttatgct
     1621 tcagggttgg gtgctgaaaa ttggccagtg tcccggcgac cattgcgcgc aaggcttctg
     1681 gtgatttggc ctgggattgt tcgttcatcc cgactccttt tttgtataga taaaccatca
     1741 gctgatagtt tacctgaaga atatagagaa gtacttactt aacattttcc catttggtac
     1801 tatctaagcc cttttcacta ttaagaagta atgcctacta tgactcaagt cgcgaagaaa
     1861 attctggtga cgtgcgcact gccgtacgct aacggctcaa tccacctcgg ccatatgctg
     1921 gagcacatcc aggctgatgt ctgggtccgt taccagcgaa tgcgcggcca cgaggtcaac
     1981 ttcatctgcg ccgacgatgc ccacggcacg ccgatcatgc ttaaagctca gcagcttggt
     2041 atcaccccgg agcagatgat tggcgaaatg agtcaggaac atcagactga tttcgcaggc
     2101 tttaacatca gctatgacaa ctatcactcg acgcacagcg aagagaatcg ccagttgtca
     2161 gaacttatct actctcgtct gaaagaaaac ggttttatta aaaaccgcac catctctcag
     2221 ctgtacgatc cggaaaaagg catgttcctg ccggaccgtt ttgtaaaagg cacctgcccg
     2281 aaatgtaaat ccccggatca atacggcgat aactgcgaag tctgcggcgc gacctacagc
     2341 ccgactgaac tgatcgagcc gaaatcggtg gtttctggtg ctaccccggt aatgcgtgat
     2401 tctgaacact tcttctttga tctgccctct ttcagcgaaa tgctgcaggc atggacccgc
     2461 agcggtgcgt tgcaggagca ggtggcaaat aaaatgcagg agtggtttga atctggcctg
     2521 caacagtggg atatctcccg cgacgcgcct tatttcggtt ttgaaattcc gaacgcgccg
     2581 ggcaaatatt tctatgtctg gctggacgca ccgattggct atatgggctc tttcaagaat
     2641 ctgtgtgaca agcgcggcga cagcgtaagc ttcgatgaat actggaagaa agattccact
     2701 gccgagctgt atcacttcat cggtaaagat atcgtttact tccacagcct gttctggcct
     2761 gccatgctgg aaggcagcaa cttccgcaag ccgaccaacc tgtttgttca cggctatgtg
     2821 acggtgaacg gcgcgaaaat gtccaagtct cgcggcacct ttattaaagc cagcacctgg
     2881 ctgaatcatt ttgacgccga cagcctgcgc tactactaca ccgccaaact gtcatcgcgc
     2941 attgatgata tcgatctcaa cctggaagat ttcgttcagc gcgtgaatgc cgatatcgtg
     3001 aacaaagtgg ttaacctggc gtcccgtaac gctggcttta tcaataagcg ttttgacggt
     3061 gtgctggcaa gcgagctggc tgacccgcag ttgtacaaaa ccttcactga tgccgctgaa
     3121 gtgattggcg aagcgtggga aagccgtgaa tttggtaaag ctatccgtga aatcatggcg
     3181 ctggctgacc tggctaaccg ctatgtcgat gaacaggctc cgtgggtggt ggcgaagcag
     3241 gaaggtcgcg atgccgatct gcaggcgatt tgctcaatgg gcatcaacct gttccgcgtg
     3301 ctgatgactt acctgaaacc ggtactgccg aaactgaccg agcgcgcaga agcattcctc
     3361 aatacagaac tgacctggga tggtatccag caaccgctgt tgggccataa agtgaatcca
     3421 ttcaaggcgc tgtataaccg catcgatatg aaacaggttg aagcactggt ggaagcatcc
     3481 aaagaggaag taaaagccgc tgccgcgcca gtaactggcc cactggcaga tgatccgatt
     3541 caggaaacca tcacctttga cgactttgct aaagttgacc tgcgcgtggc gctgattgaa
     3601 aacgcagagt ttgttgaagg ttctgacaaa ctgctgcgcc tgacgctgga tctcggcggt
     3661 gaaaaacgca atgtcttctc cggcattcgt tctgcttacc cggatccgca agcactaatt
     3721 ggtcgtcaca ccattatggt ggctaacctg gcaccacgta aaatgcgctt cggtatctcc
     3781 gaaggcatgg taatggctgc tggtcctggt gggaaagata tcttcctgct aagcccggat
     3841 gccggtgcta aaccgggtca tcaggtgaaa taatccccct tcaaggcgct gcatcgacag
     3901 cgccttttct ttataaattc ctaaagttgt tctcttgcga ttttgtctct ctctaacccg
     3961 cataaatact ggtagcatct gcattcaact ggataaaatt acagggatgc agaatgagac
     4021 actttatcta tcaggacgaa aaatcacata aattctgggc ggtggagcag caaggcaacg
     4081 agttacatgt cagttggggc aaagtcggca ctaacgggca aaaccaggta aaaagctttg
     4141 ctgatgctgc ggcggcggaa aaagcaaagc ttaagctgat cgcagagaaa acgaaaaaag
     4201 gctatgtgga aaatgcttct gcaaacgtgc atatcacccc catcaccaaa gccactcctg
     4261 aagttgaaac ttctcctgag agtaaaaacc aacgcccctg gctggctgat gatgcggtca
     4321 ttcggctaac tgacgatatt aatcgatttg cttttcctca tcgctctcgc cccagagaga
     4381 tcaattatct gcacaaagat agtcaaatat ggcagcgcat cgcgaataac accagggcat
     4441 atgatcccgc caacaattac cgttcttatc cagaaaactg gcagcaggct tttgctgagt
     4501 tacaaaggcg aattctggat aatcaacaga cagggagtgc gcaatctgat gcggcattgc
     4561 tctggagttt ctggaattct tactctgcag atgaactagt cgatgactta atcattcgct
     4621 gtggtatgga aagtgccgtt gaaattgccc ttctcgctct tcaactgaga tataaaccag
     4681 taaaaggcgc agtaaccacc atcattccac ctaatcacga agcagaatcg ctaccgagtt
     4741 ggcatcaacg cctatgtcat catctttcac tcgcttcaga agatgagtgg caacgctgtg
     4801 tagataaagt actcgcggct attacgacgc tatccccagc acggcaacct tttgcggcgt
     4861 tactgctccc tgaacgcccg gatattgcca atgctatggc tctacgctat gcagatcaaa
     4921 acgttccggc gatgacctgg ttaagactgg tagtaaccga tgaagccgct ctgactgcag
     4981 ccgaaaaata cgactttcca ccgttatatc gtgattttcg cgcttatctg gcaatgttgc
     5041 tggcaaataa tggggtgagc ggtgtaagcc ggatacttac tgagtttgtg gaagagcatt
     5101 ctgacaatcc cacttatctc ttcgagcgca tcagcgagac tgaagatctt gtcaaatggt
     5161 tatggaaaac gaatcacccg gatgcgattc aaattctgat cctcggtgta attggcaaga
     5221 aaaagcacct ggaatactta agcaaagcat gtcaaaaaca tcccgctgcg gctattgccg
     5281 cttatgcaac tttgctggca atacatgaag ataaagagtg gcataaagcg cttgtcaaat
     5341 tgattaccat cacgccagag ttagtatgcg acgtcattcc ctgggttagt gctaaagcgg
     5401 caggcatctt atctgaatgt cgtcctcagt cagtagctga agaatgtgag tatgccactg
     5461 cggatatgtt gccagagctg tttgtttcgc cgccctggat gactaaagag aaaaagaaaa
     5521 attcgccggt gtttgatctt cctgtactgc cagttccttc tgtttctgac gtcactccag
     5581 agattgccaa aaaactaacc cgtacatacc ttgtcacccg cttccagcaa atagcccaac
     5641 agcaggcaac aaaacaaata ttgtttaccg acctgccgct gatggaaaaa gcaagctggg
     5701 agagacactt agtccccctc acaccagaac agcaaattct gtggtgtctg ggttttgaca
     5761 aatggcggga gagcggagaa aaaatatacg aaaaaattcc ggcgccacaa agtgccgttg
     5821 atgccctgct acgcttcgat tttccagcac tcaatgctga atttgcgcaa taccataaca
     5881 atgcttacaa aagctggaat ctcattgccc tctgttatct acctggtcaa caggccattt
     5941 cttttcttaa ccagatagtc aaagaagata actactctgg tgagggatat attctggcca
     6001 tttttggtag cgccgccatt cctgcattta tgacctgcct gcaacgtgag ccacaacggt
     6061 tgtggttttt caccttcttc cttggtgtca atgaactggc attgccaatg gcgcaacgac
     6121 ttcagaaaaa aatgtcgtat gaagatgcac gaaactggct aacggattac ccacgccatg
     6181 ccgccgccgg gctacttcct gtggcactgg gcaaacaagg aaaagatcgt gattgtgccc
     6241 gccaggcgct ccgtctgctg gtgaatttaa accagcgaga aacgattgag gaaatcgccc
     6301 aaggatacaa ccaacctgat gttttagctg cgctggcaac attatttgat agcgagccgc
     6361 tggaagaata tcccgctaaa atcgccccac tgcccggctt ttatcagttc accttatggc
     6421 gcagaccacg gcttaaaagt aacaaccagc ctctgccaga tgacgctatg cgccacctcg
     6481 gcataatgct gagctttcca cgcgacatta ccccctacgc agggcttgcg atcatcaaag
     6541 aaaccttcac ccgcgaatca ctggctgaat ttggctggga tctgtatacc gcctggacag
     6601 aagctggcgc acccgcaaaa gaaaactggg catttacctc gctggggatt ttaggcaatg
     6661 acgacaccgc gcgtaaatta accccgctca tccgcacctg gccgggtgaa tcccagcata
     6721 aacgcgcggt ttacgggctg gatgtgttag ccagtatcgg tagcgacatt gcgctaatgt
     6781 tgcttaatgg cattgcgaaa aagattaaat tcgttgcatt acaggaacat gcctgcgaca
     6841 aaatcaacat ggtcgctgaa aatcgcgggc tgactatggc tgaactggaa gaccgcctgg
     6901 caccggattt aggacttgat agcagtggct cgttgacact ggatttcggc ccacgtcaat
     6961 ttaccgttgg ttttgacgaa actttaaaac ccgtggttcg cgacgcaaac ggcaaagttc
     7021 tgaaagattt acccaaacca aatcagagcg atgataaaac gctggcaact gacgcggtta
     7081 atctcttcaa acagttgaaa aaagatgtac gcgccatagc cagccagcag attgatcgtc
     7141 tggagcaggc tatgtgccag cgcagacgct ggacggcaga gcagttccgc ctgttcctgg
     7201 tggagcatcc gctggtacgt cacttaaccc gacggttgtt atggggggta tatactgagg
     7261 aaaacacgct gattgcctgc ttccgggtcg cagaagacag cacttacagc gatgcgcagg
     7321 atgagctatt tacgttgcca gcaggaaaca tcggtattcc gcatgtgctg gaaatatctc
     7381 ctgaatccgc cgctgcattt gggcaaattt atactgatta cgaacagctt cctccgttcc
     7441 gccaactcga tcgtggttat taccaccttg ctgataatga acgtgattcc catgaattga
     7501 tacgctggca aggacgtctt tgccaggccg ggcgcattgt cgggctggaa cgccgaggct
     7561 ggcaacgtct ggaagaaagc ggcagcgttt acgcgatgcg caaatctact ccttatggcg
     7621 atctcgaact tgaaacagaa cctttttcat taatttatgg tgaaacgggg tatggcgacc
     7681 agctaccggt tgaaagcgta aaaatcacct cgcctgataa tcgctacggt aaacaatcct
     7741 cactcacttt ttccgcgctc gacgacatca ccgccagcga actcattaac gacattgaat
     7801 cactgtttga ttaaaaggat ttagcaatga aaacctatat ttatcaggac gaaaaatcac
     7861 ataaattctg ggcagtagag cagcaggaaa atgaactgca tatcagttgg ggcaaagtcg
     7921 gcactaacgg gcaaagccag ataaaaagct ttgctgatgc ggcggcggcg gaaaaagcgg
     7981 agctgaagtt gattgcggag aaaacgaaaa agggctacgc agaagaagta tccgtgacga
     8041 caccgacatc tgcccccgtc caggttatcg catgctctga aaaagcccct ttgccgcaag
     8101 acaaaccacc atttgctgaa gaccaccttc cctggctggc agacgacgcc caaatcattt
     8161 taccgacaga ggtcgcacca accacactaa gtcatcgacg ctggcctggc gattctgtgc
     8221 cacaggagaa tgaattaact ctgctacgct ccgtcgccgc gcatactcac cggcgtttta
     8281 aaaaggtgat caccttcgat tacagcacct gttcactgga ctggcagcag gcgattacac
     8341 aagcagtggg ccttatcgac tcaccgatta gcaccgcact accaccgatg gttctggcgg
     8401 tactggttgc gctggaacaa ggcttcaatc gcaacgatca cgaagagtta atggatcaaa
     8461 ttgtccagga gggtggtctg gaatatgcca ctgaggttgt cattgcattg caagccatcc
     8521 gctttgactg gaattatgat gcccacctca ttacgtttac cccggataac aagcagcctg
     8581 gctatctgtc acgctttgcc tcggttgaaa tgcgtctgcg taaacatctc tcactagcaa
     8641 atgacgatgt atggcagcgc tgcgccgaca aactgattgc agctctcgga aacatacccg
     8701 cctggcatca gccgctggtt gcgttattgt tgccggaaaa acaagatgtg agccatgaga
     8761 ttgccagacg tctttgcgga caaaaagggt tatatgcgct ggaatggcta aaactaacgg
     8821 ccgccgacga gcaggtattg gcagaactgg ggaaatacgg cataataagc cctacacaaa
     8881 ttgggagtta gacatcatga gcaacgcaaa aacaaagtta ggcatcacaa agtacagcat
     8941 cgtgaccaac agcaacgatt ccgtcacact gcgcctcatg actgagcatg accttgcgat
     9001 gctctatgag tggctaaatc gatctcatat cgtcgagtgg tggggcggag aagaagcacg
     9061 cccgacactt gctgacgtac aggaacagta cttgccaagc gttttagcgc aagagtccgt
     9121 cactccatac attgcaatgc tgaatggaga gccgattggg tatgcccagt cgtacgttgc
     9181 tcttggaagc ggggacggac ggtgggaaga agaaaccgat ccaggagtac gcggaataga
     9241 ccagttactg gcgaatgcat cacaactggg caaaggcttg ggaaccaagc tggttcgagc
     9301 tctggttgag ttgctgttca atgatcccga ggtcaccaag atccaaacgg acccgtcgcc
     9361 gagcaacttg cgagcgatcc gatgctacga gaaagcgggg tttgagaggc aaggtaccgt
     9421 aaccacccca tatggtccag ccgtgtacat ggttcaaaca cgccaggcat tcgagcgaac
     9481 acgcagtgat gcctaaccct tccatcgagg gggacgtcca agggctggcg cccttggccg
     9541 cccctcatgt caaacgttgg gcgaacccgg agcctcatta attgttagcc
//
LOCUS       DAFGPF010000166         9570 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFGPF010000166 DAFGPF010000000
VERSION     DAFGPF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9570
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.166"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..448)
                     /locus_tag="LSX49_004707"
     CDS             complement(<1..448)
                     /locus_tag="LSX49_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HBL7170995.1"
                     /translation="MTSPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAG
                     ERTFFRRLKEGLTGEGAARQNAINASVAQGLEASLRWLTELTTSLATTNYAITRVNDR
                     VSSLVSDTARLAHYSADTREQLLILADQVHHKLNHLEEKLHRVDQVQ"
     gene            complement(445..2829)
                     /locus_tag="LSX49_004708"
     CDS             complement(445..2829)
                     /locus_tag="LSX49_004708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HBL7170996.1"
                     /translation="MHEKNIALLCDEADRLLQLNINLLRQMVEEPDVLSDSKNEKRLL
                     FDKQKALKRIEELEGEQIKTARREMVLAVVGTMKAGKSTTINAIVGQEILPNRNRPMT
                     SVPTLIRHVPGKTEPVLHLEHIQPVRNLLITLQEKLATPAGQQVAQTLQQTGDTRELL
                     DILTDDGWLKNEYHGEEEIFTGLASLNDLVRLAAAMGSEFPFDEYAEVQKLPVIDVEF
                     SHLVGMDECQGTLTLLDTPGPNEAGQPQMEVMMRDQLQKASAVLAVMDYTQMNSKADE
                     EVRKELNAIADVSVGRLFVLVNKFDEKDRNGDGADAVCQKVPAMLNSDVLPASRVYPG
                     SSRQAYLANRALHELRKNGTLPVDEAWVDDFVREAFGRMKKDYVCKDSELATEGATDL
                     WEGSLIDQLITEVILSSHSRAAALAVDSAAAKLMQNAENISEYLSLRHQGLMQSIQSL
                     QAHITSLLEDIREIADCQEQVTADVRMAMEEIDARTRELLTGVCTSLEEELNDYFRSG
                     KRKEQQMLEEENSAQPRERNAFAFFLDIFGTGNQHDRMRDFDPDSPEIKFSDRREALE
                     LMTQIESTVTSLHREAEAQFRPELEKIVSGIETGFRGTALYATENIAGRINTRLEDEG
                     FTVKISFPAVSQLQTRLAVKTNLSALMEERTETVTRRRRQSGLWGKICGAFGTSDWGW
                     ETYKEDVSRSVININTVRKEVMSLTRAYFGELQASIEQDINQPVRQEIDAFFCAFREK
                     VEQLRNTLIQSSEDHKRDQQAQERLTRRLQALNERVPELITDSKALREELETML"
     gene            complement(3047..3481)
                     /locus_tag="LSX49_004709"
     CDS             complement(3047..3481)
                     /locus_tag="LSX49_004709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7170997.1"
                     /translation="MNPSDAIEAIEKPLSSLPYPISRHILEHLRKLTRHEPVPGIMGK
                     SGAGKSSLCNALFQGEVTPVSALMTVLPGHAAIPLMTRLQDELRTESVRTQTREQFTG
                     AVDRIFDTAESVCIASVARTVLRAVRDSVVSVARAVWNWIFF"
     gene            3910..6075
                     /locus_tag="LSX49_004710"
     CDS             3910..6075
                     /locus_tag="LSX49_004710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBL7170998.1"
                     /translation="MKTQITFAALLPALASFIPLHAHASSTSEDEMIVTGNTAADTTD
                     SAAGAGFKTNDIDVGPLGTKSWIETPYSSTTVTKEMIENQQAQSVSEMLKYSPSTQMQ
                     ARGGMDVGRPQSRGMQGSVVANSRLDGLNIVSTTAFPVEMLERMDVLNSLTGALYGPA
                     SPAGQFNFVAKRPTEETLRKVTLGYQSRSAFTGHADLGGHFDENKRFGYRVNLLDQEG
                     EGNVHDSTLRRKLVSVALDWNIQPGTQLQLDASHYEFIQKGYVGSFNYGPNVKLPSAP
                     NPKDKNLALSTAGNDLTTDTISTRLIHYFNDDWSMNAGVGWQQADRAMRSVSSKILNN
                     QGDISRSMKDSTAAGRFRVLSNTAGLNGHIDTGSICHDLSLSTTGYVWSLYSAKGTGS
                     SYSWGTTNMYHPDAIDEQGDGKIRTGGPRYRSSVNTQQSVTLGDTVTFTPQWSAMFYL
                     SQSWLQTKNYDKHGNQTNQVDENGLSPNAALMYKITPNTMAYVSYADSLEQGGTAPTD
                     ESVKNAGQTLNPYRSKQYEVGLKSDIGEMNLGAALFRLERPFAYLDTDNVYKEQGNQV
                     NNGLELTAAGNVWQGLNIYSGVTFLDPKLKDTANASTSNKQVVGVPKVQANLLAEYSL
                     PSIPEWVYSANVHYTGKRAANDTNTSYASSYTTWDLGTRYTTKVSNVPTTFRVVVNNV
                     FDKHYWASIFPSGTDGDNGSPSAFIGGGREVRASVTFDF"
     gene            6086..7075
                     /locus_tag="LSX49_004711"
     CDS             6086..7075
                     /locus_tag="LSX49_004711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL7170999.1"
                     /translation="MKLSRLFPLLALLLAASLHAENTHKEVRIASPWPAQNTIIAMLG
                     YGDNIVGTSMIAKRIPLFRQSLPRIEKVAAVSVNSGHEINPEQIIALGVDMLFVPQNM
                     VVPQQALLKQAGVQVLAFEANSLRALTQRVQQTAAVLGPDAQQKALAYQRYFDRNVAL
                     VTGRLKDLPASQRVSLYHSMGNPLTTTGRPSLNQDWIDLAGGKNIAENWFGEHQQNRS
                     GEVALEKIVTANPAVIIAMNKRDADAILSSPQWASVDAVIHHRVYVNPKGMFWWCRET
                     SEEALQFLWLAKTLYPARFADVDIRKETREFYRQFFGLTLSDAQMSDVLNPPR"
     gene            7094..8152
                     /locus_tag="LSX49_004712"
     CDS             7094..8152
                     /locus_tag="LSX49_004712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL7171000.1"
                     /translation="MTVLESTLSVENRYRQLFRQRLVILAVIFIAIIASLLLDFTLGP
                     SGLPLHSLIKTLMHPSGATNGMRVIVWDIRLPYALMALLVGMALGLAGAEMQTILNNS
                     LASPFTLGVSSAAAFGAALAIVLGIGIPGVPESGFIPANAFLFALLSALLLDSLTRWT
                     RVPTSGVVLFGIALVFTFNALVSIMQFVADEDTLQGLVFWTMGSLARASWEKLAVLAA
                     AMAIVLPWSLRRAWQLTALRLGEERAMSFGIDVRRLRLGSLLRISLLAALSVAFVGPI
                     GFIGLVAPHISRLLLGEDHRFYLPGSILIGGLVLSLASVASKNIIPGVILPVGIVTSL
                     VGVPFFLSIVMRHRGSMS"
     gene            8149..8916
                     /locus_tag="LSX49_004713"
     CDS             8149..8916
                     /locus_tag="LSX49_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7171001.1"
                     /translation="MSGLTINALCAGYGKRRIIEHLSISTLPRGEVTVLLGPNGCGKS
                     TLLRALAGLNRASGEAWLNEENLLSLPFARRAEKVVFLPQSLPQGVHLQVLESVVVAQ
                     RASGAGQNQAQAIALLEELGIAHLAMNYLDSLSGGQKQLVGLAQSLIRRPELLLLDEP
                     LSALDLNYQFHVMDVVSRETRRRNMVTLVVLHDINIALRHAAQVIMLKEGKLIDSGDP
                     QTVIHAESLAQVYGVRGRVERCAQGRSMVIVDGAIEK"
     gene            8970..9227
                     /locus_tag="LSX49_004714"
     CDS             8970..9227
                     /locus_tag="LSX49_004714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001163787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171002.1"
                     /translation="MQHIDRLNVIKALVLLEDEQIVRFNIAANDNASQIHMLVDGLGV
                     GLTHEPVAAGMISHRTACHRSRQHDRPAHSYFYYLSAYQVA"
BASE COUNT         2150 a         2508 c         2560 g         2352 t
ORIGIN      
        1 gctgaacctg gtcaacacgg tggagttttt cttcaagatg attcagttta tggtgaacct
       61 gatcggccag gatgagtaac tgctcccgtg tatctgcgga ataatgcgcc agcctggcag
      121 tatcactgac cagtgaactg accctgtcgt ttacccgggt aatcgcgtag tttgtggtgg
      181 caagtgacgt tgtcagctcc gtcagccagc gcagggacgc ctcaaggccc tgtgcaaccg
      241 aagcattgat ggcattctgc cgtgcagcgc cttcgccggt cagtccctct tttaaacgcc
      301 ggaagaacgt gcgctctccg gccgtgcgga tatgctcctg tgcaacatcg attccgtttg
      361 cgaaatcaac cacaaatttt tcaggaagac aggtgagtac ctgacatacc cggttatcag
      421 caatttgttg aataaatggt gaagtcacag cattgtctcc agctcttccc tcagcgcctt
      481 actgtcagta atgagctcag gaaccctttc atttaatgcc tgaagtctcc tggtaagccg
      541 ttcctgtgcc tgctgatcgc gtttatgatc ttcagagctc tgaatcagcg tgttacgcag
      601 ttgttcaact ttctccctga atgcgcagaa aaaggcatcg atttcctggc ggacgggctg
      661 gttaatatcc tgctcaatgg atgcctgcag ctccccgaaa tatgcccggg tcagtgacat
      721 aacttccttc ctgacggtgt tgatattgat aacactgcgg ctcacatcct ctttataggt
      781 ttcccagccc cagtcactgg tgccaaacgc tccacaaatc tttccccata aaccactctg
      841 ccgacggcga cgggtgacgg tctccgttct ttcctccata agcgcactca gatttgtttt
      901 taccgcgagc cgggtttgta actgactgac tgccggaaaa ctgattttta cggtaaagcc
      961 ctcatcctcc aggcgggtat tgatgcgacc ggcaatgttt tctgtggcgt acagggccgt
     1021 gccacgaaaa cctgtttcaa tcccgctgac gattttctcc agctcaggcc ggaactgtgc
     1081 ttcagcctca cggtgcaggc tggtcacggt cgattcgatt tgcgtcatca gttcaagggc
     1141 ttccctgcga tcactgaatt ttatttcggg gctgtcggga tcaaagtccc gcatcctgtc
     1201 atgctgattt ccggttccga aaatatcgag aaagaaagcg aatgcgtttc tctcccgggg
     1261 ctgcgctgaa ttttcttcct ccagcatttg ctgttctttg cgtttaccgc ttctgaaata
     1321 gtcattcagc tcctcttcca gtgaggtgca gacccccgtc agtaattccc gggttctggc
     1381 atcgatctcc tccatggcca ttctgacatc agcggtcacc tgctcctgac agtctgctat
     1441 ttcccggata tcctcaagca ggctggtgat atgcgcctgc agtgactgaa tactttgcat
     1501 cagcccctga tggcgtaacg acaggtattc actgatattt tctgcattct gcatcagttt
     1561 tgcggcggca gaatcaaccg ccagtgccgc agctctggag tgtgaactca gtatgacttc
     1621 cgttatcagt tgatcgataa gtgagccttc ccacaggtct gtcgcccctt cagttgccag
     1681 ttcgctgtct ttacagacgt aatctttttt catgcgaccg aaggcttccc tgacaaaatc
     1741 atcgacccag gcttcatcaa caggaagggt tccgtttttc cgtaactcat gaagcgcacg
     1801 gttagccagg tatgcctggc gtgaggatcc gggataaacg cgggaggcgg gcagcacatc
     1861 gctgttcagc attgccggta ccttctgaca gactgcatca gccccatcgc cattacggtc
     1921 tttttcatca aatttattga ccagcacaaa caggcggccg acagacacat cagcaatggc
     1981 attaagctct ttacgaacct cctcatcggc tttcgagttc atctgggtgt agtccatcac
     2041 cgccagcacc gcagaggctt tctgcagttg atcccgcatc atcacttcca tctgcggttg
     2101 tccggcttca ttagggccgg gggtatccag cagtgtgagt gttccctggc attcatccat
     2161 ccccaccaga tggctgaatt ccacgtcgat caccggcagt ttctgcactt ctgcgtattc
     2221 atcaaaagga aattcactcc ccattgccgc agcaagacga accagatcgt ttaacgatgc
     2281 cagtccggta aagatttcct cctccccgtg gtattcattt ttgagccagc catcatccgt
     2341 cagaatatcc agcagttcgc gggtatcccc ggtttgctgc agggtctgtg cgacctgctg
     2401 tcctgccggg gtggcgagtt tttcctgcag tgtgattaat aaattgcgga caggctgaat
     2461 atgttccaga tggagaaccg gctcagtttt tccgggaacg tggcggatga gcgtcggtac
     2521 agaggtcatg gggcggttac ggttaggcag aatttcctgc cccacaatgg cgttgatggt
     2581 ggttgattta cctgctttca tcgtgccgac aacagccagc accatctccc tgcgggcggt
     2641 tttgatttgt tcgccctcca gctcctcaat tcttttcagt gctttctgtt tatcaaaaag
     2701 cagtcttttt tcgttcttac tgtcagataa cacatctggc tcctcaacca tttgccggag
     2761 cagattaatg ttcagttgca aaagtcggtc ggcttcatca caaagcaggg cgatgttctt
     2821 ttcgtgcatt atttaacctt cctgagacgc attttcatga caaccacgga ggaggtcatt
     2881 taccacaaac gatcgtttat aacgatcgat atgatagtaa cgatcgatgt attctattaa
     2941 cttgaaaaac acaacgcaag gggacacccc gggtatggct gcgtttgcat agtgttttca
     3001 tggagttaaa aatctgtaac aacagcctgg tacatcacca ccgggttcag aagaaaatcc
     3061 agttccatac cgcgcgggca acagagacca ccgagtcacg gacggcgcgc agaaccgtgc
     3121 gtgcaacaga ggcaatgcag acactctccg ccgtgtcaaa tatccggtcc accgcaccgg
     3181 taaactgttc acgggtctga gtgcggacag actccgtgcg cagttcgtcc tgcaggcgtg
     3241 tcatcagagg gatggcggca tgtccgggaa gcactgtcat gagtgcactg accggggtga
     3301 cctccccctg aaacagtgca ttacagagtg aggatttacc ggccccgctt ttacccataa
     3361 tgccaggcac gggttcgtga cgggtgagtt tgcgcagatg ttccaggatg tgacgggaaa
     3421 tcgggtaagg cagggaggag agcggttttt caattgcctc aatggcatca gacggattca
     3481 tacatgtatt cccagtgaaa aaagacaaaa ccccgtgcac cggaaaggtg gcgggggatt
     3541 cacggagata atatctttct gaaattattt tgaatgcagg tatatgtggc tgatttgtat
     3601 cagctaatga gtacaggtct gaatctaatc tgacagtccg ctttgtgcca aaggcggacg
     3661 ctcaagtaga tactgtcctg acagtatgcg gtaatcagag ttgttatata ttacttgcgt
     3721 ccaaaccagc tttctgacaa cccggccgct cctgctttca acaacgcgcc gccatacttt
     3781 tatgctgcaa agagcggaga cagaaggtta gcgtaatttg taaataactt acattcacgt
     3841 gtgatctgga tcataatttt gcctatgcac cgatcgtaat ataaatattt acataacgat
     3901 cagtgattca tgaaaactca aataactttc gctgcgcttt tgccagcatt agcgtctttc
     3961 ataccgcttc atgctcatgc ctcgtctact tctgaagatg aaatgattgt cacgggcaac
     4021 accgccgccg acaccaccga ttctgccgcc ggtgccggtt tcaaaacgaa cgatatagat
     4081 gtcggcccgc tgggaacgaa atcctggatc gaaacaccat attccagcac cactgttact
     4141 aaagagatga ttgaaaatca gcaggcgcaa agcgtcagcg agatgctgaa atactctccc
     4201 agtacgcaaa tgcaggcgcg cggtggaatg gatgtcgggc gtccgcaaag tcgggggatg
     4261 cagggcagcg tggtggccaa cagccgtctg gacgggctga atatcgtttc aacaaccgcg
     4321 tttccggtgg aaatgcttga gcgcatggat gtgcttaaca gtttgaccgg cgcgctgtac
     4381 ggcccggcga gcccagcagg gcagtttaat ttcgtggcga agcgcccaac cgaagagacg
     4441 ctgcgtaaag tgacgctggg ctatcaaagc cgcagtgcgt ttaccggcca tgccgatctg
     4501 ggtggccatt ttgatgaaaa caaacggttt ggctatcgcg tgaacctgct tgatcaggaa
     4561 ggggaaggca atgtgcatga cagcacgctg cgtcgcaaac tcgtttccgt tgcgctcgac
     4621 tggaatattc agccgggcac tcagctacag ctcgacgcca gccattacga atttatccag
     4681 aaaggctatg tcggtagctt taactatggg ccgaacgtca aactgccgtc tgcgccgaat
     4741 ccgaaggaca aaaatctggc gctcagcact gcgggcaacg acctcactac cgataccatc
     4801 agcactcgcc tgatccacta ctttaacgac gactggtcca tgaacgctgg cgtgggctgg
     4861 cagcaggctg accgcgcgat gcgtagtgtt tccagtaaaa tactcaacaa tcagggcgat
     4921 atctctcgtt cgatgaagga ttccaccgct gccggacgtt ttcgcgtcct gagcaacacc
     4981 gccgggctga atggtcatat tgataccggc tctatctgcc acgatctgtc actttctacc
     5041 acgggatatg tctggtcgct ttatagtgcc aaaggaacag gttccagcta tagctggggt
     5101 acaacaaata tgtatcaccc ggatgcgata gatgagcagg gcgatggcaa aatccgcacc
     5161 ggcgggccgc gataccgctc cagcgtaaat actcagcaga gcgttacgct cggcgatacg
     5221 gtgacattta cgccgcagtg gtcggcaatg ttctatctca gccagagctg gctgcagact
     5281 aaaaactacg ataagcacgg taatcaaacg aaccaggttg atgaaaatgg tttaagtccg
     5341 aacgccgcgc tgatgtataa aattacccct aacacaatgg cctacgttag ctatgccgat
     5401 tcgctggagc agggcggtac cgcaccgacg gatgagagcg taaaaaatgc cggtcaaacg
     5461 ctaaacccgt atcgcagcaa gcagtatgaa gtggggctaa aatcggacat cggcgagatg
     5521 aatctaggcg ccgcgctgtt ccgactggaa cgtccgtttg cctatcttga tacggataac
     5581 gtgtataaag agcagggtaa ccaggttaac aacggccttg agttaaccgc tgccgggaat
     5641 gtgtggcagg ggctgaatat ttacagcggc gtgaccttcc tcgacccgaa actgaaagat
     5701 acggcgaatg cctcaaccag caataaacag gttgtcggcg tgccgaaagt gcaggccaat
     5761 ctgttggcgg aatacagttt gccgtccata ccggaatggg tttacagcgc taacgtccat
     5821 tatacgggca aacgcgcggc gaacgatacc aacacctctt acgccagcag ctataccaca
     5881 tgggatttgg gaacgcgtta caccacgaaa gtgagcaacg tcccaaccac tttccgcgtg
     5941 gtggtaaaca acgtgtttga taaacattac tgggcttcta tcttcccatc gggtaccgat
     6001 ggcgataacg gttccccaag tgcgtttatc ggcggcggcc gcgaagtgcg tgcatccgtc
     6061 accttcgatt tctgatggat aaatgatgaa actctcccgt ttatttccgc tgctggcgct
     6121 gctgctggcg gccagcctgc acgcagaaaa tacgcacaag gaggtgcgta tcgcgtcacc
     6181 gtggccggcg caaaatacca ttattgccat gctggggtac ggcgataaca ttgtcggaac
     6241 ctcgatgatt gcaaaaagga tccccctgtt tcgccagagc ctgccgcgca tagagaaagt
     6301 cgcagcagtt agcgtaaaca gcgggcatga aatcaatccc gaacagatta tcgcgctggg
     6361 ggtcgatatg ctttttgtac cgcagaatat ggtagtgcct caacaggcgt tgctgaaaca
     6421 ggctggggtg caggtgctgg cgtttgaggc gaattcactg cgggcgttaa cgcagcgcgt
     6481 acagcaaacg gcagcggtgc tggggcccga tgcgcagcaa aaagcgctcg cctatcaacg
     6541 ctacttcgat cgcaacgtgg ccctggtcac cgggcgcctg aaagatcttc ctgcgtcaca
     6601 gcgcgtgtcg ctctatcaca gtatgggcaa tccgctgacc accaccggta gaccctcgct
     6661 aaaccaggac tggattgacc tggccggcgg caaaaatatc gctgaaaatt ggtttggcga
     6721 gcatcaacaa aaccgttcgg gtgaagtcgc gctggagaaa attgtcactg ccaatccggc
     6781 ggttatcatc gcgatgaaca agcgcgacgc ggatgccatt ctgagttctc cgcagtgggc
     6841 aagcgtggac gcggtcattc atcatcgcgt ttacgttaat ccgaaaggaa tgttctggtg
     6901 gtgccgtgaa accagcgaag aggcgctgca atttttgtgg ctggcgaaaa cgctttatcc
     6961 tgcgcgattt gctgatgtgg atatacgcaa agagacgcgt gagttttatc ggcagttctt
     7021 tggcctgacg ttaagcgatg cgcagatgag cgatgtgctc aatccgccgc gctaacggag
     7081 gctgtgaaaa accatgactg tattggaaag tacgctgtcg gtcgagaacc gctatcgcca
     7141 gctttttcgc cagcgtctgg taatactggc ggttattttt atcgctatca ttgcttcgct
     7201 gctgctcgat ttcaccctcg gcccctcagg gctcccttta cattcgctga taaagacttt
     7261 gatgcatccg tccggggcga ctaacggcat gcgggttatc gtttgggaca tccgtttgcc
     7321 ctatgcgctg atggcgctcc tggtaggaat ggcgctgggt ttggccgggg cagagatgca
     7381 aactattctg aataactccc tcgccagccc gtttacgctt ggcgtttcgt cggcggcggc
     7441 ctttggcgca gcgctggcga ttgttctggg catcggtatt cccggcgttc ccgaaagcgg
     7501 gtttataccg gcaaacgctt ttctttttgc gctcctgtcc gccctgctgc tcgatagtct
     7561 gacccgctgg acgcgcgtgc cgacgtcggg cgttgtgctg tttgggattg cgctggtgtt
     7621 taccttcaat gcgctggtgt ccattatgca gtttgtcgcc gatgaagata ctttgcaggg
     7681 cctggtgttc tggacgatgg gcagcctggc tcgcgcatca tgggagaaac tggcggtgct
     7741 ggcggcggcg atggcgattg ttttaccctg gtcgctgcgt cgtgcctggc agcttaccgc
     7801 gctacgcctc ggcgaagagc gggcgatgag ttttggcatt gatgttcgcc gtttgcgcct
     7861 gggttccctg ctgcgcatca gcctgctggc ggccctttcg gttgcgtttg tggggccaat
     7921 tggctttatt ggcctggttg caccgcatat ttcccgcctg ttgctgggag aagatcatcg
     7981 cttttatttg cccggaagca tccttatcgg tgggctggtg ctatcgctgg cctcggtagc
     8041 gtcgaagaac atcattcccg gtgtcatttt accggtagga attgttacct cgctggtagg
     8101 cgttccgttc tttctgagca ttgtaatgcg tcatcgaggg agtatgtcat gagcgggctt
     8161 acgattaatg cgctgtgcgc cggttacggc aaacggcgga ttattgagca tctgtcgatt
     8221 tctacgctgc cgcgcggcga agtcactgta ctgctggggc ctaatggctg cggtaaatca
     8281 acgctactgc gcgccctggc cgggctaaat cgcgccagtg gcgaagcctg gctgaatgaa
     8341 gagaatctct tatcgctgcc gtttgctcgt cgggctgaaa aagttgtgtt cctgccgcag
     8401 tccctgccgc agggcgtgca tttacaggtg ctggagtcgg tggttgtcgc ccagcgcgcc
     8461 tccggcgccg ggcaaaatca ggcgcaggct atagcgctgc tcgaagagct aggcatcgca
     8521 catctggcaa tgaactacct cgatagcctg tccggcggtc agaagcagct ggtggggctt
     8581 gcacagtcgc ttattcgccg ccccgaatta ttattgctgg atgaaccact gagcgcgctg
     8641 gatctcaatt atcagttcca tgtgatggat gttgtatcgc gcgaaacgcg aagacgcaat
     8701 atggttacgc tggtcgtctt acacgatatc aatatcgcac tgcggcatgc cgcccaggtc
     8761 atcatgctga aagaggggaa acttatcgac agcggcgacc cgcaaacggt gatccatgca
     8821 gagagccttg cgcaggtata cggcgtacgc gggagagttg aacgttgtgc tcagggaaga
     8881 tcgatggtga tagtggatgg tgcaatcgaa aaatagtcgg attaacgtgg ttgcttcagc
     8941 ctcaggtaaa gatcaatagg aagtctgtaa tgcaacatat agaccgcctt aatgtcatta
     9001 aagcacttgt gcttctagaa gatgagcaga ttgttcgttt taacatcgct gcgaacgata
     9061 acgcctcgca gatccacatg ctcgttgacg gtctgggcgt cgggctgaca catgagcctg
     9121 tcgctgccgg aatgatttcg caccggacag cttgtcaccg ttctaggcaa catgacagac
     9181 ctgcgcattc ctatttctat tatctatccg cctaccaagt tgcttaatgt caggctaagg
     9241 ccctttaatg actggatttc agaccgattt tctggacagc cgagcgggta aatcgcagta
     9301 cactgacagc tagacaataa agctccggtt catgtttgaa ccatgtgtag tgaatgtccg
     9361 ctgttcgctc acaacggacc ttcagttcag ccgctccggc cgcttcatgc catgaatgta
     9421 cgcagccagt cagaatatta aggtgcggat ttcagttcac ttgtcagcgc cagtgacaca
     9481 agacagtaat gaccaacaat ttggtattga cacaacaagt tgcggccccg gttcgtggag
     9541 gagattaaac gactgtagcc ggggccactg
//
LOCUS       DAFGPF010000167         9381 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFGPF010000167 DAFGPF010000000
VERSION     DAFGPF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9381
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.167"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(57..458)
                     /gene="crl"
                     /locus_tag="LSX49_004715"
     CDS             complement(57..458)
                     /gene="crl"
                     /locus_tag="LSX49_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HBL7171003.1"
                     /translation="MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLRE
                     FHEKLRELLATLNLKLEPADDFRDEPVKLTA"
     gene            complement(516..1760)
                     /gene="frsA"
                     /locus_tag="LSX49_004716"
     CDS             complement(516..1760)
                     /gene="frsA"
                     /locus_tag="LSX49_004716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HBL7171004.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFSHGAQLPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILEVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     ALRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            complement(1852..2310)
                     /gene="gpt"
                     /locus_tag="LSX49_004717"
     CDS             complement(1852..2310)
                     /gene="gpt"
                     /locus_tag="LSX49_004717"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL7171005.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            2571..4028
                     /gene="pepD"
                     /locus_tag="LSX49_004718"
     CDS             2571..4028
                     /gene="pepD"
                     /locus_tag="LSX49_004718"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HBL7171006.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFNLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
                     KSLVDTYQEILKNELAEKEKNLALLLDSVANDKAALTATSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            complement(4084..4698)
                     /locus_tag="LSX49_004719"
     CDS             complement(4084..4698)
                     /locus_tag="LSX49_004719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HBL7171007.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEATRQDVAVTVLETET
                     GRYSDTLRSALISLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAALKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     gene            complement(4695..5834)
                     /locus_tag="LSX49_004720"
     CDS             complement(4695..5834)
                     /locus_tag="LSX49_004720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBL7171008.1"
                     /translation="MGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVG
                     MPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILARKYNADKFEKRLSD
                     LDDVAEESWLEENLPSAFAQHPWHNSLGSIGGGNHFAELQQIDQIIDAELFARAGLDA
                     QHLQLLVHSGSRGLGQSILQRHIASFSHHGLPEGSDDALRYIAEHDDALAFARINRQL
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWLVKPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVLAGLIIPVARLRPVLTLKNSGGKKG"
     gene            complement(6024..6476)
                     /locus_tag="LSX49_004721"
     CDS             complement(6024..6476)
                     /locus_tag="LSX49_004721"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL7171009.1"
                     /translation="MNNIQIRNYQPGDFQQLCAIFLRAVTMTASQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAQPVGFITRIGHYIDMLFVEPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGTWFTNFYMRYKPQH"
     gene            complement(6473..7528)
                     /gene="dinB"
                     /locus_tag="LSX49_004722"
     CDS             complement(6473..7528)
                     /gene="dinB"
                     /locus_tag="LSX49_004722"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBL7171010.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPTFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKSDLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            complement(7599..8522)
                     /gene="lafU"
                     /locus_tag="LSX49_004723"
     CDS             complement(7599..8522)
                     /gene="lafU"
                     /locus_tag="LSX49_004723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HBL7171011.1"
                     /translation="MRKTGNHRERGAKTTIVRRQIKKNHAGHHGGAWKVAFADFTLAM
                     MALFMTLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHPPKPATVAVPEE
                     TEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKD
                     DQNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLS
                     GDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTKSASDT
                     LYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            complement(8525..9379)
                     /gene="motA"
                     /locus_tag="LSX49_004724"
     CDS             complement(8525..9379)
                     /gene="motA"
                     /locus_tag="LSX49_004724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HBL7171012.1"
                     /translation="MLGLLVVLGCVFGGYFEAGGQLVAIWQPAEMIIILGAGFGAMII
                     GNPKHVLKEIAHQIKGVISKKQLGPEFQRQLLMCLYELLEMVQNGGLRMLDQHIEQPE
                     ESTIFQKYPLVLTQKRLVTFIADNFRLMAMGKIDAHELEGILDQELDTAEESLLTPSR
                     SLQRTAEAMPGFGICAAVLGIIITMQSIDGSIALIGLKVAAALVGTFLGVFICYCLMD
                     PLANAMEQQARAEHSLLECVRTVLVAQAGGKPTLLAVDAGRKLLHLASKPTFANLDAW
                     VNAMLEQE"
BASE COUNT         2250 a         2557 c         2288 g         2286 t
ORIGIN      
        1 atgacctatc agttttaatg gatattgccg gatgtgatgc atccggcaca tttcattcac
       61 gccgttaact tcaccggttc atcacgaaaa tcatctgccg gttccagctt cagattcagc
      121 gtcgccagca gctcacgcag cttctcgtga aattcacgca gggtgtgctc cagtcgttca
      181 accacttcgg catcttttat ctgaacactc gtccagtcgc ctgctttatc gaacagacca
      241 aactggtaac tgtaggtaaa acgggattcc tgcgcttcca gttccatcca ccagccccag
      301 aactcacgca cttccggtgc cggtttcacg ttgacgcata cagccagaca atcgaaaaag
      361 aatcgattat cttcgcactt accttcacga atatacgggc ctagtgcggt aaattttttg
      421 actaatctgc tcttcgggtg tccactcggt aacgtcattg caatctcctg ttgtgatgca
      481 actgttttac caaattggta aaatttagca aatttttaac acaaacgttt ttcgatccag
      541 tctgtgattt cctgaaggcc tttgtcaaaa ttccgataca ccgggttaaa tgggatctct
      601 aataatttac cgtcagcaga tgacgacgtg attaagcgtg agtcctcttc cgggctgaac
      661 ggatcgttct tccagtagcc tgataacatt ggcgttgggc agcgacgtcc cagcaaccct
      721 tgcactttta atgaatagcg attcagctcc acgcgcaacg cttcgtcaga agcatcatgc
      781 atccccaaac gactcgccag aacgtcaaga tacatttccg gcacctgttg ctggcactta
      841 aaatcactca acagggtatg aactaccgga ccaagacagg caaccgcttt cagacgcggc
      901 gattcaaggt atgccagacg tacggcaacg ttagcgccga aacggaaacc aaaggccgcg
      961 acgcgagtgt gatccaccca cggtacgtta ggcaacgcct ttaaaacgtg ctgatgcaac
     1021 aggctggagt cctgggtgag cttccatttt gaagaaaagc ccaccgacgg catatcaata
     1081 gtcagcatcg caatgccgcg cagcgcaaaa taacgttcat acaggctgta atagtctgtc
     1141 tgcatcgcat ccagaccacc acacattaat actgtcggga acgggccatc gcctttcggc
     1201 atatgcaaaa agccggtgat gggcgcaccg ccgggtacgg taaactccat ctgccgcatc
     1261 gtgcccggca gacgctgagc ggcctcttca taggcgcggt ttgacaaagc ctgcgcttgc
     1321 tcggccaggt catctccttt cagatgagga taggcagcaa tgttgtacaa cgtagccgca
     1381 tgcagccagt gtcgaccgct gagttgcgga tcttcttccg cacaggcttt ttgttgccac
     1441 accatcgcct gggtagccca ctcataaatc cagttgccgc cgcggtagcc aatcaccgta
     1501 tcgtataaat catcgtcggt acgttcggca tcgctcatca caatacgcgc ctggacttcg
     1561 aggatttcac gggggtcaat gccgcgccag atccacatca gacggttaat catgcgatac
     1621 cagtgaggga tggttttacc atcaagggcc gactgcacag gcagttgtgc gccgtgacta
     1681 aagcggcgga ctagcgtcga ggtttcagga tgtttaaagc ggggtttgaa cagggtttcg
     1741 ctcaggtttg cctgtgtcat agatgcagcc tccagaatac ttactggaaa ctattgtaac
     1801 ccgcctgaag ttaaaaagaa caacgcccgg cagtgccagg cgttgaaaag attagcgacc
     1861 ggagattggc gggacgaata cgacgcccat atcccacggc tgttcgatcc aggtattttg
     1921 cgggatatca acaacataat catcaaccag cggacgacca gccggttttg cgaagatggt
     1981 gacaaagtgc gcttttggat acatttcacg aatcgcaacc gcagtaccac cggtatctac
     2041 caggtcatca ataacgatga agccttcgcc atcgccttct gcgcgtttca gcactttaag
     2101 ctcgcgctgg ttgtcgtgat cgtagctgga aatacaaacg gtatcgacat gacgaatacc
     2161 cagttcacgc gccagtaacg cacccggtac cagaccgcca cggcttacgg caataatgcc
     2221 tttccattgt tcagaaggca tcagtcggct tgcgagttta cgtgcatgga tctgcaacat
     2281 gtcccaggtg acgatgtatt tttcgctcat gtgaagtgtc ccagcctgtt tatctacggc
     2341 ttaaaaagtg ttcgagggga aaataggttg cgcgagatta tagagatctg gcgcactaaa
     2401 aaccagtatt tcacatgagt ccgcgtcttt ttacgcactg cctctccctg acgcgggata
     2461 aagtggtatt ctcaaacata tctcgcaagc ctgtcttgtg ttgacaacat tttctgctaa
     2521 ccctgtgacc tgcaatactg ttttgcgggt gatcgacaag gagacttaac gtgtctgaac
     2581 tgtctcaatt atctccacag ccgctgtggg atatttttgc caaaatctgt tctattcctc
     2641 acccgtccta tcatgaagag caactcgctg aatacattgt tggttgggca aaagagaaag
     2701 gtttccatgt cgaacgcgat caggtaggta atatcctgat tcgtaaacct gctaccgcag
     2761 gtatggaaaa tcgtaaaccg gtcgtcttgc aggcccacct cgatatggtg ccgcaaaaaa
     2821 ataacgacac cgtgcatgac ttcactaaag atcctatcca gccttatatt gatggcgaat
     2881 gggttaaagc gcgcggcacc acgctgggtg cggataacgg cattggtatg gcctccgcac
     2941 tggcggttct ggctgacgaa aacgtggttc acggcccgct ggaagtgctg ctgaccatga
     3001 ctgaagaagc cggtatggac ggtgcgttcg gcttacagag caactggttg caggctgata
     3061 ttctgattaa caccgactcc gaagaagaag gtgaaatcta catgggatgt gcggggggta
     3121 tcgacttcac ctccaacctg catttagatc gtgaagcggt tccagctggt tttgaaacct
     3181 tcaatttaac cttaaaaggt ctgaaaggcg gtcactccgg cggtgaaatc cacgttggcc
     3241 tgggtaatgc caacaaactg ctggtgcgct tcctggcggg tcatgcagaa gaactggacc
     3301 tgcgtcttat tgatttcaac ggcggcacac tgcgtaacgc catcccgcgt gaagcctttg
     3361 cgaccattgc tgtcgcagct gataaagtcg acgccctgaa atctctggtg gatacctatc
     3421 aggagatcct gaaaaacgaa ctggcagaaa aagagaagaa tctggcattg ctgctggact
     3481 ccgtagcgaa cgacaaagct gcattaacgg cgacatctcg cgataccttt attcgtctgc
     3541 tgaacgccac cccgaacgga gttatccgta attccgatgt agccaaaggc gtggttgaaa
     3601 cctccctgaa cgtcggtgtg gtgaccatga ccgacaataa cgtagaaatt cactgcctga
     3661 tccgttctct gatcgacagc ggtaaagact acgtagtgag catgctggat tcgctgggta
     3721 aactggcagg tgcgaaaacc gaagcaaaag gcgcatatcc tggctggcag ccggacgcta
     3781 actctccggt aatgcatctg gtacgtgaaa cctatcagcg tctgttcaac aagacgccga
     3841 acatccagat tatccacgcg ggcctggaat gtggtctgtt caaaaaaccg tatccggaaa
     3901 tggacatggt gtctatcggg ccaaccatca ccggtccaca ctccccggat gagcaagttc
     3961 atatcgaaag cgttggccat tactggacac tgctgactga actgctgaaa gaaattccgg
     4021 cgaagtaatt atttgatttg ctgccggatg gcgtttaacg ccttccggca gtttcatcct
     4081 tcattatcct tcgataaaag ccatccctgt gaacgttcgt cgcgggttgc cacgttcaat
     4141 ctggtgatgg aacattcgcc gctgcgattt cagcgccgcg ctattttcct gttgctgttg
     4201 ttccagcttc caggcaatca gtaatcgcgc cagccgtttg ttagcatgct gactgcgctc
     4261 tgactgaacc ttcacgctaa taccggatgc cagatgcgtg gcgcgtaccg ccgagtcggt
     4321 tttattgaca tgttgaccgc ccggccccga cgaacgcagc gtctcataac ggattgcatc
     4381 cgattgttcc tgctcatcag cggtaaaacg cccaatgccc agaaaccagt ttttgcgccc
     4441 atgatgaggc cgatacggac tcggacaaat ccactgaata gtgccgcacc agctttcgct
     4501 tagagcccat gcgttatcgc catccagaga aatcagcgcc gaacgcagtg tgtcagagta
     4561 gcgacccgtt tctgtttcca gcaccgttac cgcgacgtcc tgtcgggtag cttctttaat
     4621 cagcctgtcc agtgcttttt tcactgcgag acaacattct tccggcccct gagcagagga
     4681 gagttgtagc aagatcatcc ttttttccct ccactgtttt tgagcgtcag caccgggcgc
     4741 agtcgcgcga caggaataat taacccagcc agcaccagac attgcaccac gctttcagcc
     4801 gatttatagg cttgtggcgc ttcttcaaag atgagttgtt tatcgcgaca aattacccga
     4861 ctgccaagtt cagtccgcga gagttgcgtc gccgtgtatt tcgctgccag acgcccttta
     4921 cactcggtgc gcccccattt acgccccgcc ccatgcgcca gcgagtggag cgttttttcg
     4981 ttcgcaacag gtttaaccag ccaggagtaa tcgccgcgtg aaccgggaat aatcaccaga
     5041 ccgttgtcat ccggcgtggc gcctttacga tgcaaccagc cctgttgatc gccgatttgg
     5101 cacgcgctaa caaagttatg cgccacatcc agaaccggac ttccggtggc cttaacttgt
     5161 tgcattatgc gcaaagcgat cagctggcga ttaatacgcg caaacgccag cgcatcgtca
     5221 tgttccgcaa tataccgtag cgcgtcgtca ctgccttcag gcaaaccatg atgcgaaaac
     5281 gaggcaatat gccgctgtaa aatagactgc cccaatcccc tcgagccgct atgaaccagt
     5341 agttgcagat gctgcgcatc cagaccagcc cgtgcaaaca gttccgcgtc gataatttga
     5401 tcaatctgtt gcagttctgc gaagtggtta ccgccaccga tggagccaag cgagttgtgc
     5461 cacggatgct gtgcaaatgc tgacggcagg ttttcctcca gccagctttc ttcagcaacg
     5521 tcatccagat ctgataatcg cttttcaaac ttatcggcgt tgtatttgcg agcgagaata
     5581 tctgtttgcc atagcgccat gccgcagccg atatcattgc cgaccagtgc cgggtaaaaa
     5641 cgaccaacag agaagaacgc tgcgccaatc gggtagccgc gtccgggatg taaatctggc
     5701 atccccacaa cgcgctgcat gttgggtaaa tttgccgtgg tgtgtaattg ttggatcgct
     5761 aaactctcga tccacaggtc atcagatgcg atggtaaata ccgcatcgga taagggacga
     5821 atatatttgc ccatgtacca ttccatttat gaataaaaat caggaaatgg cagacgaatc
     5881 cagggcaaga aaaaagaatt aatcctggaa aggtctgcaa agagtcattg ataaaggatt
     5941 tgtcatgatt tacctccttg cagtttgtgg aataagaaaa cgcgcacata ctagacgggc
     6001 gttattttca ttgcaagctg gatttaatgt tgcggtttat atcgcatata aaaattagta
     6061 aaccacgttc cccggcattc aacgcgctgc tgcttaactg tctgaaaacc ataacgttca
     6121 aaaaagggtt ttgcggttat gctggcgtcc accgtaagtt cggattcaga cttaatcaat
     6181 ggttttaaca aagcgctggc aactccgcgt cgggtgtatt ccggttcaac aaataacata
     6241 tcgatataat gtccaatgcg ggtaataaaa ccaaccggtt gtgcattaat aactgcaacc
     6301 cgcacttgtg atttcgcgag tttctccttc cagcgagatt cgtcaatctg cgcccaggcg
     6361 gcaatttgct gtggagaata gtgctgactc gccgtcatcg taacagctcg aaggaaaata
     6421 gcgcatagtt gctgaaaatc accaggctga tagtttctta tttgtatgtt attcataatc
     6481 ccagcaccag ttgtctttcc atttgcgggt caagcaacgt cacatgcagc cccaccagtc
     6541 gcacaccgcg cccgccgcgg cgttcatccc aggttttacg cgcggtggcg attagatcag
     6601 atttattcag ccgcggccag acgtgttcct gggtggtttg ctgaaaatcg tcgaacttta
     6661 atttcacccc ctggcgggca atcagcaaat caggttttac ctttgccaaa cgacgctcca
     6721 gttcagggta aagccgctcg atgatcgctt cacattcaga ccagtgatga atatcttccg
     6781 ccatcgtacg ttctacaccg acggattttc gcaacctttc gctgttaacg tcgcgttcgt
     6841 caatgccctg actacgctcc cacaaaatgc ggccaaattt gccaaagcgt ttaagcagca
     6901 tcaccagatc acacttttgc acatcaccgc aggtccgcag ccccatcgct tccagttttg
     6961 ccgccgagac tttgccgacg ccgggaattt ttgccagcgg taaggtttgt aaaaatgtcg
     7021 gaacttctgc cggcgtaatc acaaactggc cgttgggttt attcatgtcg gaggcgattt
     7081 tggcgagaaa ctttactggt gccacgcccg cagacgccgt cagttgcagc tcgttgaaga
     7141 tcgtctggcg gatttcctgg gcgatgaggg tcgcagaacc gtggcaatgg acgctatcgg
     7201 tgacatcgag ataggcttca tccagtgata acggttcaat gcgcgaggta tagcgcgaga
     7261 aaatttcgcg gatatgattt gaggcttctt tgtaggcgtc aaagcgccct ggaagcaagg
     7321 tgagatgcgg gcataatttg agcgccatcc ctgtcggcat agcgctacgt acgccaaatt
     7381 tacgcgcggg ataattggcg gtgctgatca ccccccgtcg ttcgcggctg ccgccaatag
     7441 caatagggat atcgcgcagg gcgggattgt cgcgcatctc caccgctgcg aaaaagcagt
     7501 ccatatccac atgaatgatt ttacgcattg ctcacctctc aatactggta aagtatacag
     7561 tgatttcagg gtttgagaaa tgcgtaaaga ttcagcattt aacgcgttcg ctgcgaaagc
     7621 acctgctgct tatccagctt ttgcaccagc ggctgcacca ctttatcccc atgctgacca
     7681 aagtattgat acagcgtatc ggacgcactt ttggtcagca ccataatctc aatgcgccgg
     7741 ttgcccgcgc tttgcggatt tttggcatcc agcagcatct ggtccgccat tgcacttacc
     7801 tgcatcactt tatcttccgg cattccggcc tcttccagca cccgacgagc tgaaagcgcg
     7861 cgatcgcccg aaaggttcca gttgttgtag atattgtttt tgtaggccat cgcatcggta
     7921 tgcccggtaa taataatttt gttatcgagc gagtcgaaca ctggcgcaag ctccaccagc
     7981 aaagttttaa agaacggcat aatcttcgcg ctgccgcgtt cgaacatatt gcggttctgg
     8041 tcgtctttaa tcagcacgcg taatccctgg ggaacaatct ccatctccag attcgcttcc
     8101 atatgcgcat cacgggcgat ggtattgata ctggttgcca gctcgccaag ctcggtggcg
     8161 gatttcttct tcagcagcgc cgttttctcg ttgacgtcgc gcgctttttt ctccgtctct
     8221 tccggcaccg ccacggtggc aggttttggc ggatgagacg ggctgatttt atttaacggc
     8281 gacaacccac caccgttaaa aatcgactgc ccgtgcagcg cggcgataat gctttcacgc
     8341 tcggatttac tgacgctgtt gacaatccac agcgtcataa atagcgccat cattgccaaa
     8401 gtaaagtcgg cgaacgccac cttccacgcc ccgccgtgat gcccggcatg attctttttg
     8461 atctgccgcc ggacgatggt ggtttttgcc ccacgttcgc ggtggttgcc cgtctttctc
     8521 atgcttattc ttgctccagc atcgcattca cccacgcgtc gaggttggcg aaggtcggtt
     8581 tggacgccag atgcagcagc ttacgcccgg cgtccaccgc cagcagcgtc ggtttgccgc
     8641 ctgcctgcgc caccagcaca gtgcgcacgc attccagcaa agaatgttcc gcccgcgcct
     8701 gctgttccat ggcgttggct agcgggtcca tcaggcagta gcagataaac acgcctaaaa
     8761 acgtccccac cagagccgcc gccactttca ggccaatcag agcgatagat ccatcaatcg
     8821 actgcatggt gatgatgatg cccagcaccg ccgcgcaaat accaaatccc ggcatcgctt
     8881 cggcggtacg ttgcagcgag cgcgacggcg ttaacaggga ctcttccgcg gtgtccagtt
     8941 cctgatcgag aatgccttcc agctcatggg cgtcgatttt acccatcgcc atcaggcgaa
     9001 agttatcagc aataaaggtc accagccgct tctgggttaa caccagcggg tatttctgga
     9061 aaatggtgct ctcttccggc tgctcaatat gctgatccaa catccgcaga ccgccgtttt
     9121 gcaccatttc gagcaactca tacaggcaca ttaatagctg acgctgaaac tccggcccga
     9181 gctgtttttt actgatcacg cctttaattt gatgggcaat ctctttcagc acatgtttcg
     9241 ggttaccaat aatcatcgcc ccgaaaccgg cacccaaaat aatgatcatt tccgccggtt
     9301 gccagatagc cactaattgc ccgcccgctt caaaataacc gccaaatacg cagccgagca
     9361 ccaccagtaa acctaatatt t
//
LOCUS       DAFGPF010000168         9258 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFGPF010000168 DAFGPF010000000
VERSION     DAFGPF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9258
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.168"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            56..289
                     /gene="papI"
                     /locus_tag="LSX49_004725"
     CDS             56..289
                     /gene="papI"
                     /locus_tag="LSX49_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major pilus subunit operon transcriptional
                     regulator PapI"
                     /protein_id="HBL7171013.1"
                     /translation="MSEYMKNEILEFLNRHNGGKTAEIAEALAVTDYQARYYLLLLEK
                     EGMVQRSPLRRGMATYWFLKGEMQAGQNCSSTT"
     gene            792..1160
                     /locus_tag="LSX49_004726"
     CDS             792..1160
                     /locus_tag="LSX49_004726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171014.1"
                     /translation="MAESGFISLELSRSQAPVTISKTAILFAEADNDTPESTHLHCVG
                     GITHTVNGVFNDIAELLPRFIKTHRRDNGQPAVAIHDWNVSYIEKGNDASAVVYFTES
                     GSSITVRESYEDIIAKFHAL"
     gene            1299..1508
                     /locus_tag="LSX49_004727"
     CDS             1299..1508
                     /locus_tag="LSX49_004727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171015.1"
                     /translation="MADSADIAYENEQFSMSIRLKNRIRNRLPETGFCYNCGEPVKTG
                     LFCDGDCREDYEKRERFGQINTDNV"
     gene            1729..1902
                     /locus_tag="LSX49_004728"
                     /pseudo
     CDS             1729..1902
                     /locus_tag="LSX49_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            complement(2210..2686)
                     /locus_tag="LSX49_004729"
     CDS             complement(2210..2686)
                     /locus_tag="LSX49_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator"
                     /protein_id="HBL7171016.1"
                     /translation="MLIIIMTRDRYLEYGLMRILSGYQVTTGRELFNAGKQRQSLPED
                     SYVILCDRNLERLTYSMFCGRRFLVIPVSSVRCLTDIRQTIRRGAWLFGHTARPLTRT
                     EMVVVFGVVFHDYGFTFLADRLGITMKTVCAHLYNAMEKNGMRGVSIKYLCNTIDR"
     gene            complement(2749..2955)
                     /locus_tag="LSX49_004730"
     CDS             complement(2749..2955)
                     /locus_tag="LSX49_004730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171017.1"
                     /translation="MLNYRIRSVQLFIVNGRADRAQVRLECDDEAVFECYLLAEGEGE
                     LKELSLSELEERALMYAADSFRYE"
     gene            complement(3407..3775)
                     /locus_tag="LSX49_004731"
     CDS             complement(3407..3775)
                     /locus_tag="LSX49_004731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011579242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171018.1"
                     /translation="MPDQFASLGTAACVVDKAGNGMALSSWSASDATGAVTVGVVAKG
                     THQNSMAQGEFSCTTRENEVYIRYDSGVTNPVSPRGPDKIRGPGGISDGAWDTEAATI
                     RQLNPLTDEVYSGISGRITA"
     gene            complement(4051..5130)
                     /locus_tag="LSX49_004732"
     CDS             complement(4051..5130)
                     /locus_tag="LSX49_004732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBL7171019.1"
                     /translation="MKRIFFIPLFLILLPKLAVAGPDDYVPSQIAVNTSTLPGVVIGP
                     ADAHTYPRVIGELAGTSNQYVFNGGAIALMRGKFTPALPKIGSITYTFHQGNSRDSSD
                     FDIYDIGVSGLGIIIGMAGYWPATPLVPINSSGIYIDPVGANTNPNTYNGATASFGAR
                     LFVAFVATGRLPNGYITIPTRQLGTILLEAKRTSLNNKGLTAPVMLNGGRIQVQSQTC
                     TMGQKNYVVPLNTVYQSQFTSLYKEIQGGKIDIHLQCPDGIDVYATLTDASQPVNRTD
                     ILTLSSESTAKGFGIRLYKDSDVTAISYGEDSPVKGNGSQWHFSDYRGEVNPHINLRA
                     NYIKIADATTPGSVKAIATITFSYQ"
     gene            complement(5127..7661)
                     /locus_tag="LSX49_004733"
     CDS             complement(5127..7661)
                     /locus_tag="LSX49_004733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBL7171020.1"
                     /translation="MNANNLSCLIYCRCSLLLFAALGLTVTNHSFAAEEAEFDSEFLH
                     LDKGINAIDIRRFSHGNPVPEGRYYSDIYVNNVWKGKADLQYLRTANTGAPTLCLTPE
                     LLSLIDLVKDTMSGNTSCFPASTGLSSARINFDLSTLRLNIEIPQALLNTRPRGYISP
                     AQWQSGVPAAFINYDANYYQYSSSGTSNEQTYLGLKAGFNLWGWALRHRGSESWNNSY
                     PAGYQNIETSIMHDLAPLRAQFTLGDFYTNGELMDSLSLRGVRLASDERMLPGSLRGY
                     APAVRGIANSNAKVTIYQNAHILYETTVPAGPFVINDLYPSGYAGDLLVKITESNGQT
                     RMFTVPFAAVAQLIRPGFSRWQMSVGKYRYANKTYNDLIAQGTYQYGLTNDITLNSGL
                     TTASGYTAGLAGLAFNTPLGAIASDITLSRTAFRYSGVTRKGYSLHSSYSINIPASNT
                     NITLAAYRYSSKDFYHLKDALSANHNAFIDDVSVKSTAFYRPRNQFQISINQELGEKW
                     GGMYLTGTTYNYWGHKGSRNEYQMGYSNFWKQLGYQIGLSQSRDNEQQRRDDRFYINF
                     TLPLGGSVQSPVFSTVLNYSKEEKNSIQTSISGTGGEDNQFSYGISGNSQENGPSGYA
                     MNGGYRSPYVNITTTVGHDTQNNNQRSFGASGAVVAHPYGVTLSNDLSDTFAIIHAEG
                     AQGAVINNASGSRLDFWGNGVVPYVTPYEKNQISIDPSNLDLNVELSATEQEIIPRAN
                     SATLVKFDTKTGRSLLFDIRMSTGNPPPMASEVLDEHGQLAGYVAQAGKVFTRGLPEK
                     GHLSVVWGPDNKDRCSFVYHVAHNKDDMQSQLVPVLCIQHPNQEKT"
     gene            complement(7669..8394)
                     /locus_tag="LSX49_004734"
     CDS             complement(7669..8394)
                     /locus_tag="LSX49_004734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBL7171021.1"
                     /translation="MLRFVLFFFTLSVSAVVQGSVVIMGTRVVYPATQKSISIRLNND
                     NESPALVQSWLDDGDAAAPPESVHVPFIITPPIFRMDSKSGQTVRIVYTGESLPKDRE
                     SLFYLNVLDIPAKPRAKKDSDNSEQRNNNYLQLAIRSRIKFFFRPAHLKLTPNDAYLK
                     VTWHQEEGRIKAVNPTPYYITYNKIAVDQNKHLTPVEHGGMIPPFSSTVFALKGRTAP
                     ASKVSWVIVNDYGGYQQGESVLE"
     gene            complement(8459..9007)
                     /locus_tag="LSX49_004735"
     CDS             complement(8459..9007)
                     /locus_tag="LSX49_004735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_110925516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBL7171022.1"
                     /translation="MKIKVIALATFVSAVFAGSAMAYDGTITFTGKVVAQTCTVNTSD
                     KDLAVTLPTVATSSLKDNAATSGLTPFAIRLTGCATGMNSAQNVKAYFEPSSNIDLAT
                     HNLKNTATPTKADNVQIQLLNSNGTSTILLGEADNGQDVQSETIGSDGSATLRYMAQY
                     YATGQSTAGDVKATVHYTIAYE"
BASE COUNT         2636 a         2173 c         1890 g         2559 t
ORIGIN      
        1 cgttgataac agagagcatg atttttatta ttcgaagaaa ctttgttaca gtgagatgag
       61 tgaatatatg aagaatgaaa tactggaatt tctgaacagg cataatggag ggaaaaccgc
      121 agaaattgcg gaggcgctgg cggtaacgga ttaccaggca cgctattacc tgttattact
      181 ggaaaaagaa ggtatggttc agcgctctcc attaaggcga ggcatggcga catactggtt
      241 tttgaaagga gagatgcagg cgggacaaaa ctgttcttcc acaacttaat aactcagttt
      301 gtgggcatgc ttcactgaaa cagataaaag ctacatcaga gtgcagattc aattttgcag
      361 cattcgtcac aaaataaaaa tccagcattt tatgtcagaa tacctcacat gataataaaa
      421 cctgtccggt tttactgcat ggccagacat tataaaaaag caaatcctgt aaactccatt
      481 cagcctcctt gctgtccggt aacggaggct gttttttcgt tacgcctttc cccggcagca
      541 tcagtagcag taatttatag attctacgaa ctgagactgt ctgtccaggg agaacatacg
      601 catcccggcg caatgctccg gtcatttaca acctgcttct gatcataaac gccacgatcc
      661 ttggctctca cagatttcgg gagaagaaag ttagtttaca ggcagaaacc actcataata
      721 ttgacatgag aaagattttc tgttatacaa aaaacatatg aaatgatata acatcacaaa
      781 ctggagtttt tatggcagaa tccgggttta tttctctcga attatcccgc tcacaggcgc
      841 ctgttacaat tagcaagaca gctatactct ttgcagaagc agacaatgat accccggagt
      901 caactcatct acattgcgtt ggtggtatca ctcataccgt aaatggtgtt tttaacgata
      961 ttgcagaatt acttccgcga ttcattaaga cgcaccgtcg ggataatggt cagcccgcag
     1021 tggctatcca tgactggaat gtttcataca ttgaaaaagg caacgatgct tctgctgttg
     1081 tttacttcac agaatcaggc tcaagtataa ccgtccgtga atcttacgaa gacataatag
     1141 caaagtttca cgctctttag tcaacacctg tgctgagaat taaagcaggg gcaggataca
     1201 attatcctgc ccctgccgtt aaagattata caatgagtat tactttgtaa tatttcggtg
     1261 gtgggttata aagatgtggt ctcctcagag gatcgtttat ggcagatagt gcagatattg
     1321 cttatgaaaa tgaacaattc agcatgagca tcagactaaa aaatcgtatc cggaatagac
     1381 tccctgaaac aggattctgc tataactgcg gagaacctgt taagactgga ttgttttgtg
     1441 atggtgactg tcgggaagat tatgagaaac gtgaacgatt tggacaaata aatactgaca
     1501 atgtttaaaa gcaatacaat tactgatatc tctttcagac ttcagaatta aagaaaactg
     1561 cccgaatgtt atccgaaaag cagctgtaat tagtaatgct cttatcagga gtgaaacatc
     1621 acctcccaga atacatcaga acagaaggat aacagttatc cgatgtgacg gctataatgt
     1681 gccgacacag agggttactc accgatctcc ttcacggtaa tacgcagctc tgagcatggt
     1741 ggtgagcggg gagtgctact gtacagcctg atcgggacgt gcaaactgaa cgacgaggat
     1801 ccagaaaact accttcgcca tgtgtttggc gtcatagctg actggccggt caaccatgtc
     1861 agcgaactgc ttccgtggcg catagcactg cccgctgaat aacacatccc cgtcaatacg
     1921 gccctcgctg tactcttacc gtggatccag cagtccactt atttgcatga ataaacgagt
     1981 ggtcgcagac cacgcaacat cattcaaatc ccccgctaat attacaggta acttcagtgt
     2041 gtatggaaac acctcattaa ctgttatcac aaataaaacg catacctgtt ccatatgaaa
     2101 tttatcacgc ctgactacat aacattaatt atccggagaa ctgggatgcc cgtgacacag
     2161 catgcacaga aatccccgtc gcaacagcct ttatcagaaa accatctttt taccggtcta
     2221 tggtgttgca gagatattta atactgacgc cgcgcatacc atttttctcc atcgcattgt
     2281 aaagatgcgc acataccgtc ttcatggtta tccccagccg gtctgccaga aaggtaaacc
     2341 cgtagtcatg gaaaacaacc ccgaagacca ccaccatctc tgtccgggtc agtggccttg
     2401 ccgtatgtcc gaacagccac gctccacggc ggatggtttg cctgatatct gtcaggcatc
     2461 tcacagagga aacaggaatg acaagaaacc gacgcccaca gaacatagag tatgtaagcc
     2521 tttccagatt acggtcacag agaatcacat aactgtcttc gggaagtgac tgacgttgct
     2581 ttccggcatt aaacagctct ctgcctgtcg tgacctgata tccgctcagt atacgcatca
     2641 ggccatattc cagatatctg tcccgggtca taataataat cagcatactc tctgcccctt
     2701 gtatcccgga taccggctcc gtttaccatt accggtataa ctgacttatc attcataacg
     2761 gaaactgtct gccgcataca tcagcgcccg ctcttccagc tctgacaggc tcagttcttt
     2821 cagttcccct tccccttcag caagaagata acattcaaaa acggcttcat cgtcgcattc
     2881 cagacgcacc tgcgccctgt cagcccgacc gtttacaata aatagctgca ctgaccttat
     2941 gcgatagttc agcatataca ctcttcctct cagatcttca ggaatacccg ggaacagtca
     3001 gttatgccat cggggagaaa aacaggcagc gaatcattac ttcataccga aaactgcctc
     3061 cccggtgact caggcccggg ttcagaacta ccagttgaca cccacattcc aggaaacata
     3121 gccgccactg aaagtagtac ctgcctttaa gcagtctgct tggcactata cccgcccaca
     3181 gccgctatgg cgttaaattt atcctcactg tacggctccc gcttcatttc ctcgtgattc
     3241 tcattaatca gccctgctga ctgttcagac gctccgcatg catctccagc acctctcccg
     3301 gggaaagcag cccccgggtg ttacggttta tggccaccgt gttccggatg atattctccc
     3361 tgttctctgc agcgaccgta tctgtatggt cacacgcctt aagcacttat gctgtaatcc
     3421 gtccactgat gccactgtac acctcatccg tcagcgggtt cagttgcctg atagtggctg
     3481 cttccgtatc ccatgcacca tcactgatac caccgggacc ccggatttta tccggtcccc
     3541 gcggactgac agggtttgtg acacctgagt catatctgat gtaaacttca ttttcacggg
     3601 ttgtacagga aaactccccc tgtgccattg aattctgatg tgtgcccttc gccacaactc
     3661 ccaccgtcac ggcaccagtt gcatctgacg ccgaccaact gctgagagcc atgccgtttc
     3721 cggctttgtc gacaacgcat gctgcagttc ccagcgatgc gaactggtct ggcatgcatt
     3781 cacgaaccaa cagcagtggt gctacgtccg gatgcaattc gcatgagctc caaccgcggt
     3841 tgtaagttca gcagcccggg cctctgcccc cggcacagtc gcataagtat tcgataccgt
     3901 gcgacaccat taccttcagg atacgccacg gacccgtcac cctacgaaaa cgccggaaca
     3961 ccggcaatca gcaaaggcag cagtgataaa agactgatat atttcctgtc attatttttc
     4021 atattaattt aactcctgat taaccggttt ttattgatat gagaaagtaa tagttgcaat
     4081 agccttcaca cttccaggtg tagttgcatc agcaattttt atataattgg ctcttaaatt
     4141 gatatgtgga tttacctctc ccctgtaatc ggagaagtgc cattgactgc catttccttt
     4201 cacaggggag tcttcaccat agctgatggc agttacatca ctgtctttat atagcctgat
     4261 gccaaatcct tttgcagtgg attcactgct taaggtcaat atatctgttc tgttcactgg
     4321 ctgtgatgca tctgtcaatg tagcataaac atcaattcca tccgggcatt gtaggtgtat
     4381 gtcaatttta cctccctgta tttctttata caaagatgtg aactgtgatt gatatacggt
     4441 atttaatggc accacatagt ttttttgccc catggtacat gtctgactct gtacctgaat
     4501 gcgcccacca tttaacataa caggtgctgt cagtccttta ttatttaaac ttgtacgttt
     4561 tgcttccaac aaaatagtac caagctgcct ggtgggtatt gttatatatc cattgggtaa
     4621 tcttcccgtt gcgacaaaag caacaaacaa acgagctccg aagcttgctg tcgcaccgtt
     4681 ataagtattg gggtttgtat tggcacctac agggtcaata tatatacctg agctatttat
     4741 ggggaccaga ggcgttgcgg gccaatagcc cgccatgcca ataataatac ccagtccgga
     4801 tacaccaata tcatagatat caaaatcaga tgaatcacgg ctgtttcctt gatggaaagt
     4861 atacgtaata cttccaattt taggcagtgc gggtgtaaac tttccacgca tcagagcgat
     4921 ggcaccgcca ttaaaaacat actggttact tgttcccgcc agctctccta tcacccgggg
     4981 ataggtatgg gcatcagcag gaccaatcac aacacctggc aatgtggatg tattaaccgc
     5041 tatctgcgaa ggcacataat catccggacc cgctaccgcc agcttaggga gtaaaattaa
     5101 aaacaatggt atgaaaaaga ttcttttcat gttttttcct gattagggtg ctgtatacac
     5161 agaacaggaa cgagctgaga ttgcatatca tctttattgt gtgcaacatg atatacaaat
     5221 gaacatctgt ctttattatc tggtccccat acaacgctga gatgaccttt ttcagggagt
     5281 cccctggtaa ataccttccc ggcctgagcg acatatccgg ccaactgtcc atgttcatcc
     5341 agaacttcag aagccattgg agggggattg ccagtagaca tacgaatatc aaataacaga
     5401 cttcttcctg ttttagtgtc aaatttcact aacgtggcgc tattagcacg aggaatgatt
     5461 tcctgctccg tcgccgataa ttcaacattc aaatctaaat tggagggatc gatgctaatt
     5521 tgatttttct catagggtgt aacataagga acaacaccat ttccccaaaa atccagacga
     5581 ctaccagagg cattattgat gacagccccc tgagctcctt cagcatggat aatggcaaaa
     5641 gtatcactca ggtcattact caatgtcact ccataggggt gtgcgaccac cgctcccgac
     5701 gcaccaaatg acctttgatt attattctga gtatcatgcc cgactgttgt ggttatattt
     5761 acataaggtg aacgataacc cccattcatt gcataaccgg aaggcccgtt ttcctggctg
     5821 tttcctgaaa taccataaga gaactgatta tcctccccgc cagtaccact aattgatgtc
     5881 tgaatactat ttttctcttc tttgctataa tttaaaacag tggaaaacac cgggctttga
     5941 acacttcctc ccagagggag agtaaaatta atataaaatc tgtcatcacg gcgttgttgc
     6001 tcattatctc ttgactgaga caatccaatt tgatagccga gttgtttcca gaagttgctg
     6061 taccccatct ggtattcatt acgacttcct ttatgtcccc agtaattata ggttgttcct
     6121 gttaaataca tcccacccca tttttcacct aattcctggt tgattgaaat ctggaattga
     6181 ttcctgggac gataaaacgc tgtacttttt acagaaacat catcaataaa cgcgttgtga
     6241 ttagctgata gcgcatcctt cagatgataa aaatcttttg atgaataacg ataagccgcc
     6301 agagttatat ttgtgtttga ggctggaata ttgatgctat aacttgagtg cagactataa
     6361 cctttacgcg ttacaccgga atacctgaat gctgttctgg acaatgtaat gtcagatgct
     6421 atagcaccca gaggggtatt aaaggccagg ccagctaacc ccgctgtata tcctgaagct
     6481 gtggtaagac cactgtttaa agtaatatca ttcgtcaggc cgtattgata ggtgccttgt
     6541 gctattaaat cattatatgt tttattcgca taacgatact ttcccactga catttgccag
     6601 cgactaaatc cgggacgaat gagttgagca acggccgcaa aaggaaccgt gaacattcgt
     6661 gtctggccat tagactctgt tatcttaacg agaaggtcac cagcatatcc actgggatat
     6721 aaatcattga tgacaaatgg tccggctggc accgtcgttt catagaggat atgagcattt
     6781 tgataaatgg ttactttagc attactgtta gctattcccc ggacagcagg agcatagcca
     6841 cgtaaagagc cgggtaacat tcgttcatcc gatgctaacc tgactccccg caaactgagg
     6901 ctatccatta gctcaccatt cgtataaaaa tcccctaatg tgaattgtgc tctcaatggg
     6961 gcaaggtcat gcattatact tgtttctata ttctgatatc cggcaggata gctattattc
     7021 cagctctcac tgccacggtg gcgcaaagcc catccccaca aattgaatcc agcttttaat
     7081 cccagataag tctgttcgtt actcgtcccg gaagagctat actggtaata gttagcatca
     7141 tagtttataa atgctgcagg aacaccactt tgccactgag caggggaaat atatcctctt
     7201 ggacgtgtat tcagcagtgc ctgagggatt tcgatattca accttaaagt cgataagtca
     7261 aaattaattc tggctgaaga aagccctgtt gacgccggaa agcaggaggt gtttcccgac
     7321 atagtatctt tgactaaatc aatcaatgaa agcagctcag gcgtcaggca taacgtcgga
     7381 gcaccggtat tggcagtacg taaatactgc aaatcagcct tccccttcca tacattatta
     7441 acataaatat cagaataata cctgccctca ggcacagggt taccatgact aaagcggcgg
     7501 atatcaatag catttatccc tttatccaaa tgcaaaaact cagaatcaaa ctcagcctct
     7561 tcagcagcaa atgaatggtt tgttactgtt aaccctaatg cagcaaaaag cagaagagaa
     7621 caacgacagt aaatcaggca tgacagatta ttagcgttca ttattacctt actccagaac
     7681 agattctcct tgctgatatc ctccgtaatc attaacaata acccaggaaa ctttgctggc
     7741 tggcgcagtt ctgcctttaa gtgcaaatac tgttgaagag aaagggggaa tcattccacc
     7801 atgttcaaca ggcgttaagt gcttattctg gtcaactgca attttgttgt aggttatgta
     7861 ataaggtgtt ggattaactg ctttaattcg gccttcctcc tggtgccagg tcactttcag
     7921 ataagcatca tttggtgtta acttcaggtg agcaggacga aagaaaaatt ttatgcgact
     7981 acgaatagct agttgcaaat aattattatt ccgctgctct gagttatcgg agtctttttt
     8041 tgccctgggc tttgctggaa tatccagaac atttagatag aaaagagatt ctcggtcttt
     8101 cggtagtgac tcgcctgtat atacaattct gactgtttgt cctgatttag agtccatacg
     8161 aaatattggc ggagtaatga taaaaggaac gtggactgac tcagggggag ctgctgcatc
     8221 tccatcgtct aaccaggact ggactaatgc cggagattca ttgtcattat ttaaacgtat
     8281 gctaatactc ttttgagtcg ccggataaac aacacgggtt cccatgataa ctacactacc
     8341 ctgaacaact gcagatacag atagagtaaa aaaaaacagc acaaacctta gcatggtatc
     8401 tccagaagaa aacagggcag tatttcctgc ccagaaatac aaaagagtaa aaagtttttt
     8461 attcgtaggc aatggtataa tggaccgtcg cttttacatc ccctgcggta gattgtcctg
     8521 ttgcataata ctgggccata taacgcaatg tggcacttcc atcagatccg attgtctcag
     8581 actggacatc ttgcccatta tccgcttccc ccaaaagaat agttgaagtt ccattactat
     8641 ttagcaactg aatctgtaca ttatccgctt tagttggagt agcagtattt tttaaattat
     8701 gtgtagctaa gtcaatgtta cttgaaggct caaagtacgc tttaacattc tgagcactat
     8761 tcataccagt tgcacaacca gttaaacgaa tggcaaaggg tgtcagccct gacgtagcag
     8821 cattgtcttt tagagatgaa gtggcaacag tgggtaaagt tactgctaag tctttgtcgc
     8881 ttgtattaac tgtgcaggtc tgagctacaa ctttaccggt aaacgtaatt gttccgtcat
     8941 aggccatagc tgaaccagca aacacagcag aaacaaatgt agccaatgct ataactttta
     9001 ttttcataaa atgaattcct gtttaattcc agtattgatc atttgttcag caatcatccc
     9061 caacaaaaca atcattttca aaatgttttt accgatcgat aaccagcgta tgatagattg
     9121 cacatatcat gattgctaaa acgatcggga aaaacgatca aaaaccatat ttattgtgtt
     9181 ggtaatgaca aaagatatgc tttaccctga aatgagcgac ctattcatga aaatatgtag
     9241 gtctgtattt gattacta
//
LOCUS       DAFGPF010000169         8855 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFGPF010000169 DAFGPF010000000
VERSION     DAFGPF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.169"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..868
                     /locus_tag="LSX49_004736"
     CDS             <1..868
                     /locus_tag="LSX49_004736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS600 family transposase"
                     /protein_id="HBL7171023.1"
                     /translation="KYALIEQWRQQFPIEAMCQVFGVSRSGYYNWVQHEPSDRKQSDE
                     RLKLEIKVAHIRTRETYGTRRLQTELAENGIIVGRDRLARLRKELRLRCKQKRKFRAT
                     TNSNHNLPVAPNLLNQTFAPTAPNQVWVADLTYVATQEGWLYLAGIKDVYTCEIVGYA
                     MGERMTKELTGKALFMALRSQRPPAGLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRK
                     GNCYDNAPMESFWGTLKNESLSHYRFNNRDEAISVIREYIEIFYNRQRRHSRLGNISP
                     AAFREKYHQMAA"
     gene            913..1335
                     /locus_tag="LSX49_004737"
                     /pseudo
     CDS             913..1335
                     /locus_tag="LSX49_004737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291745.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1751..3283
                     /locus_tag="LSX49_004738"
                     /pseudo
     CDS             1751..3283
                     /locus_tag="LSX49_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013317439.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(3317..3826)
                     /locus_tag="LSX49_004739"
                     /pseudo
     CDS             complement(3317..3826)
                     /locus_tag="LSX49_004739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
     gene            3846..4168
                     /locus_tag="LSX49_004740"
                     /pseudo
     CDS             3846..4168
                     /locus_tag="LSX49_004740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000555401.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(4746..4961)
                     /locus_tag="LSX49_004741"
     CDS             complement(4746..4961)
                     /locus_tag="LSX49_004741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171024.1"
                     /translation="MWLLIFWLSSPFNVSSGDARQPTLAVHSQAFHTERACRDALHAI
                     KKENVGEFSLRGVCVSDGNTKEEAESS"
     gene            complement(4965..5324)
                     /locus_tag="LSX49_004742"
     CDS             complement(4965..5324)
                     /locus_tag="LSX49_004742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171025.1"
                     /translation="MKDNSTTATPEAWKMRFLANGTSGTWFYTDDITVTDAWLRAHPD
                     DVEVIPLCRIPPRQHSHEQHIEELRAALARMLHMHHMMLETTHYRENITDARCIREMH
                     EAPLQALNILARYPHEV"
     gene            complement(5615..5857)
                     /locus_tag="LSX49_004743"
     CDS             complement(5615..5857)
                     /locus_tag="LSX49_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171026.1"
                     /translation="MKDEIHSTSINPDVVEQFLALMNTHCKSSEEALAMLSTLCYNLM
                     VTCGIHSMDSQMLNGHGISMQLQGIDIAERPGKNIH"
     gene            6342..6501
                     /locus_tag="LSX49_004744"
                     /pseudo
     CDS             6342..6501
                     /locus_tag="LSX49_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066419.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            complement(6719..8809)
                     /gene="iha"
                     /locus_tag="LSX49_004745"
     CDS             complement(6719..8809)
                     /gene="iha"
                     /locus_tag="LSX49_004745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional siderophore receptor/adhesin Iha"
                     /protein_id="HBL7171027.1"
                     /translation="MRITTLASVVIPCLGFSASSIAAAEDVMIVSASGYEKKLTNAAA
                     SVSVISQEELQSSQYHDLAEALRSVEGVDVESGTGKTGGLEISIRGMPASYTLILIDG
                     VRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
                     ADKWLSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSVSLQVRGSTQQRQGSSVTSL
                     SDTAATRIPYPTESQNYNLGARLDWKASAQDVLWFDMDTTRQRYDNRDGQLGSLTGGY
                     DRTLRYERNKISAGYDHTFTFGTWKSYLNWNETENKGRELVRSVLKRDKWGLAGQPRE
                     LKESNLILNSLLLTPLGESHLVTVGGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDE
                     WHLTDALALTVGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLH
                     KGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAGLNANVTGFMTDFSNKIVSY
                     SINDNTNSYVNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNKGAPLSY
                     TPEHMVNAKLNWQITEEVASWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAW
                     TVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYV
                     IPERNYWMSLNYQF"
BASE COUNT         2318 a         2198 c         2138 g         2201 t
ORIGIN      
        1 aaaatacgcg ttaatcgaac aatggcgaca acaatttccc attgaagcga tgtgtcaggt
       61 atttggtgta tccaggagcg gttattacaa ctgggtacag catgaaccct cagacagaaa
      121 acaaagtgat gagcggctaa aactggagat taaggtggca catatccgca ctcgcgaaac
      181 atatggaacc cggcggctcc agacggagct ggcagagaat ggcatcatcg ttggtcgtga
      241 ccgactggca cgtcttcgta aggagctaag gctacgctgt aagcagaaac gcaagttcag
      301 agcgactacg aactcgaacc acaatctgcc agttgcgcca aatctgctga accagacgtt
      361 cgctcctaca gcaccaaatc aggtctgggt ggcggacctg acgtatgttg ccacacagga
      421 gggatggttg tacctcgctg gcatcaaaga tgtttatacg tgcgaaattg tcggctacgc
      481 catgggagag cgcatgacaa aagagctgac aggtaaagcc ctgtttatgg cgctcaggag
      541 ccagcgccca cctgccgggc taatccacca ctctgatcga ggttcacagt actgcgcata
      601 cgattaccgg gtcatacagg agcagtttgg tctgaaaaca tcaatgtcgc gtaaaggtaa
      661 ctgttacgac aacgctccga tggaaagctt ctggggaacg ctgaaaaatg agagcctgag
      721 ccactatcgt tttaataacc gggatgaagc catctcagta atacgggaat acattgagat
      781 tttctacaat cgtcagcgtc gtcactctcg tctggggaat atctccccgg cagccttcag
      841 ggaaaaatat catcagatgg ctgcttaaaa aaagaacaaa tggttgtgtc cgctattgcc
      901 agtacacctc aaactgagtt ctcatggttc cgatacggac agtataacga aacgggtatt
      961 tacatctcga tcgagaagac cattatcatt acaatcaccg tttctggtgg gtgctttaaa
     1021 aaagaataca gcattgtctc ccacatgctg gtcactgaca ccataacaga ggccaccctg
     1081 tacgaaaacg ggctgtatac gcgccacatc agactcagtc gcccagtatc tgacagcaaa
     1141 taccccttgc cacccggatc tcagctcatt aaaaatatga ccttacgact gcgcctgcag
     1201 gatcagcagg aagaaacatc cgtgacatta tttcagggaa aaataagtac cgacggaaat
     1261 aactattcca tcatcaaagg taaagtaagc tcagtacttc tgttattaaa aatgctgcag
     1321 attaatcatg cctgatctct gtcccggtat tttagcccga ggtatattct gaaatatcat
     1381 tcatcatgac cggcgtttat acaaacgcca gtcattcgct aacagcttca ccgttccttc
     1441 ccccatccag gttccgcatg agcgtgttgt aatgttcata agcgtattat caggattgtc
     1501 tggaaaattc ccgatacttt ggactattac tcctgaacaa ctgtaagcgt acagcctgaa
     1561 ccgtctggtc agaatctgac gaattagaca aagtggtgtc caccaaataa gtagtgggaa
     1621 ccaaagtgtc agatatgcag aaaaatgtga ctcccggcag gcgaaaaggc tgccctaatt
     1681 atcctcccga atttaaacag cagctcgttg ggggatgcgg acgatttcct ggactctcag
     1741 gagataaaac atgtttactg aagaagaaaa aatccgcgcc attgagcttt atttcaaata
     1801 tggtaagaag ctggctcccg tcgtacgcga actgggctac ccttcgaaaa gaaatctgcg
     1861 gcgttggatc cgctcatggg aagcaggtgg tggcgcaaaa gaatccattc gtcataagca
     1921 ccgttactcc gatgagcaaa aacaggttgc cgttgaacat tatcttaacc acggctgctg
     1981 cctggcgttt accagcagag ccctgggtta tccctgcact gatgtactcg ctcgctgggt
     2041 taatgaactt tatcccgaca gacgacgtat atttaccagt aaggccaacc cggttgcgcc
     2101 ctttgaacca gaagtcaaac gtcaggctgt catggcactc tgtacacgac aagtatcagc
     2161 cagtgagatc gccaggcgta ttggtgtcag tcgtgcggta ttgtataaat agaaagatga
     2221 aattatcggc aacagtgctt accagactat gcgtaaacat aacgaacctt ccctggaggc
     2281 agaacgcgat gcgttgcggg aggaagtcgc ccgactgaat caggaaatac gccgccggca
     2341 gatggagctg gatattctga aaaaggcgga ggaaatcata aaaaaagacc cgggcatcag
     2401 tatcagtcac ctgaacaaca gagaaaaaac aaagatcgct gatgccctga ggcaaacata
     2461 tcccctgaca gaattacttc atgttctggg ccttacccgt agcagttatt tttatcaccg
     2521 ggctgcactg aaagccggtg ataaatacgc cacgatacgt acgatgctga cagatatatt
     2581 taacagtaat taccagtgtt atggctatcg tcgcctgcat gcgatgctca ggcatgaggg
     2641 ggggcggcta tcagaaaagg ttgtacgcag acttatggtg gaggaacagc ttgtcgtcag
     2701 ccgtaaccgt cgtcgtcgct acagctcata ttgcggagaa atcggaccgg ctccggataa
     2761 ccttatcgcc agagatttta aggcgtagca acctaatcag aaatggctga cagatatcac
     2821 ggagttccaa ctccctgcag gtaaagtctg gctgtcaccg gtggtggact gcttcgatgg
     2881 aaaagttatt agctggtctc tcagtacacg ccccgatgct gagctggtca acactatgct
     2941 ggatagcgct gtcgaaacgt taaatgctgg cgaacgaccg gtgatacaca gtgacagagg
     3001 tgggcattat cgctggccag gctggctgga aagagtgaat gcagcaggtc ttattcgctc
     3061 aatgtcccgt aaaggatgtt cacctgataa tgccgcatgc gaaggttttt tcggcagact
     3121 gaaaacggaa atgtattatg ggcgtaaatg gtcgggcatc acgccagaaa agctcatgca
     3181 gcatgtagat gcttacatca gatggtataa cgagcggcgt ataaaattat cgctgggtgc
     3241 agtcagccct gaaatgtacc gccaacaatg tgggctggca taataaagca gtctaggaaa
     3301 tcgtccgcat ccccaattca ggggcggttt tttctttacg gtttttcgcc ataaagacta
     3361 ttactatcag actgacaaga ctacccgcga aagccgggag ttccgcgcca agattaacag
     3421 ccaccagata ctggggaatt aatgtactga caccacacat cagggtaatt agtccaacgc
     3481 ctcgtatagt cttcatacca ccaccgataa tcgcgacgat gacgaaagga agcagaatgt
     3541 tgaacagtgc cagttgaaga ataattgtcc cgctgagtgt ggttacaggt aaattaactt
     3601 gttcagcaag tacagagaca ggtataccta ctgccccaaa cgctgtaggg actgtattag
     3661 caaccagtga tgcaatcgct gcttttagtg ggttaaagcc cagagcaatc agtataccaa
     3721 tggggattgc taccgctgta ccgtatccgg ctgccgcctc aagaaatcca ccaaaacacc
     3781 atgagataag aagtacctgg atacgtttgt catcactaac actcgctcaa tcatttggtc
     3841 tgctatctca acagattgct ttcaacatta ttgtcagaat ctggagcaga ttgaagatcg
     3901 catacttcaa ctcgatcagg aaatatctcg cctgttacct gagtgatctc tgtgcaatct
     3961 ggtctgccag ttgcaggctc ttaaaggtgt tggtcaacta atcgcaataa ccctggttgc
     4021 tgaactgggt gatttttcgc gattttccaa tcctgaacag ctcatggctt ttctgggact
     4081 ggtgccaggt gaatattcca gcggaaacag cattcgcccc agaggaataa caaaagttgg
     4141 aaacagcgaa ctgagacatc tgctttacgg atatcaaata aattcagatt atttaacagt
     4201 aaaaccccac ttatgtgatg aatctcataa aaaagcaaag tgaagtaata atatccaatt
     4261 tatccctcat tccttaagta agcgtacact ggccgcgtac accatggcat aatgatatgt
     4321 tgttttactg atatttccgg ctggtaaaat ccccgacggc ccggctgaag ctggtgcagg
     4381 aaagcgggtt aattgtcact acgcgggata acctgtctgg ctggatacaa cgtattgcca
     4441 cagatatgca gcaactgcgt cagtccggaa tgtcagtcat ctccggggat gttggggtct
     4501 caggcacact gaccggcccc ccgtgttgtt tccgggtact gtttttgatt tatgcaacaa
     4561 agtattgcag cgtcgaatat gagctatggc cagatttttg ttaatcgtgg ttgttgcaac
     4621 atgtaaggcg aatgaccaca ctattctggc acgctcgtaa tcacgctgaa attccgcttc
     4681 ctgtgctgcc gtgaagagtt ccgaccagga catacggcga agtgtatgtc tgtcagtaat
     4741 atccgtcatg agctctcagc ttcctccttc gtatttccgt cagaaacaca aacgccccgc
     4801 agagaaaatt cgccaacatt ctccttttta atggcgtgca atgcatcgcg acaggcccgt
     4861 tcggtatgaa atgcctggct gtgcaccgcc agtgtgggct gccgggcatc accggaagag
     4921 acattaaagg gagatgaaag ccagaaaatc agtagccaca tgcgtcacac ctcgtgcggg
     4981 tatctggcca gaatattgag cgcctgtaat ggagcttcat gcatttcacg gatacaacgg
     5041 gcatcggtga tgttttccct gtaatgcgtg gtttccagca tcatatgatg catatgcagc
     5101 atccgggcca gggctgcacg gagttcttca atatgttgtt catgggaatg ctgacggggt
     5161 ggtatccggc agagagggat aacctccaca tcatccgggt gcgcgcgaag ccacgcgtca
     5221 gtgactgtaa tgtcgtcagt gtaaaaccat gtgccggatg tcccgttggc cagaaaacgc
     5281 attttccagg cttctggggt ggcggttgtg ctgttatctt tcatggtgcc accactcatt
     5341 caacaggctt aatgctgtcc aggcgcagtc tgctcagact gtcgtggctg ccacagcggc
     5401 gtcctgtact tttgctgtag cactcctgcc ccctgataca ccatgccgtt ggcgtttcgt
     5461 agaggctgac acgtcgggtt ttatctttac tggctagaag cccggtgtga gtttttgtct
     5521 ttttcatcgg tggggtacaa acgcagaaat tttgttgtca tcagtttttg cctgcagagg
     5581 cctgaaaaga cagcgttttc agaccctgtt caggttagtg aatattctta cctggccttt
     5641 cggcaatatc aatcccctga agttgcatgg atatcccatg cccattgagc atctggctgt
     5701 ccatggaatg gataccgcat gtcaccatca ggttgtaaca aagcgtactc agcatggcga
     5761 gcgcctcttc tgaggattta caatgtgtgt tcataagggc cagaaactgc tcaacaacat
     5821 ccgggttgat gctggtactg tgtatttcat ccttcattat gtgtccttgt tttttattat
     5881 tttgcatttc agaaaataac acgatgcatg taacccagaa aaccgatatg tgcacgcgta
     5941 gtcactttct ggcagattcc ggtctctgaa acaaaatacg aggtggcatg aagcggattg
     6001 tggcggacag ggaaagtgat ttgattccgg ggaaggcgct gtgcagcagt cttatccggc
     6061 agtttaaagg ggtggacgga gaccaatgag gcactggagc agattcagtg cagaggtgac
     6121 atgatttatc aaacttaatt gtgacaaaat ggcgattgag aaggtgcaat tgacttatcc
     6181 ggattcggtc gtggcgaggt ggtgaccctg cattctgcta accgggttat gagccaggag
     6241 tcagcgatag acaaagggac ttatctgacc gggcccccgg aaaaatggcg ggagagaatg
     6301 ataccttcct gctgacgaga ccggactttg agatgacgag cgatagtgcg gcagtgatgt
     6361 acagcctgat cggtagctgc aaaacttaac ggaatcgagc cggaaacgtg gctacgccac
     6421 gtgatcagtg taatcaacac ctggcctgcc aaccgcatga aagagttgtt gccctggaac
     6481 gtcactctct ctgtacacta atttttaccc cacgtccttc acggtgcgct tacactctgg
     6541 acaagtatgt aaatgataag ttaaaaataa tccgtgcatt tcctgtgacg atattagttg
     6601 ttggtaacga aatctcatta gcggatcgga aatgcactta acctaatacg ttgccactgt
     6661 tccgccagga gttacagtgg caacgtattc taccgtcagt gatagcgttt tgttattatc
     6721 agaactgata gttcagcgac atccagtaat ttcgctcagg tatcacatat cctgttgttg
     6781 atgatcccgt ctggaagtaa tcaccggcat acagcgtact cttaccggca ctgtacaggc
     6841 tcacgtcact gtaatccttg ttgagcaggt tattcaccgc agcattcagc gtcagggcat
     6901 ccgtcatctt ccacgacaga cctgcatcca ccaccgtcca ggctttcagg tattctcctt
     6961 tctcatcata cactttcttc tgtacagcgc tcagtgacga ataattctgg gtgaaacgtg
     7021 gtgttttccc gcgataacgg gcacccagcc atgatgccac ctcttcggtg atctgccagt
     7081 tcagtttcgc attcaccatg tgttcagggg tataactcag cggcgcacct ttgttatcac
     7141 catcacgttg ttcacttcgg gtccaggtgt aattcagtga cagcgtgaca tcctctgacc
     7201 acagcggcaa tgtgccggca aattccacac catgcaaccg ggcctttccg ctgtttacat
     7261 agctattggt gttatcattt atggaataag agacaatctt gttggagaag tcagtcataa
     7321 aacctgtgac attggcattc agaccggcgg ggttatcgta atacacccca gcctcataac
     7381 tgacgctctc ttccggcttc aggtcggggt taccaagtag atttgttttt ccctgcccgg
     7441 atacaccact aatcccttta tgtagctgcc ccattctggg tgccttatat cccgtggtca
     7501 caccgccttt cagcgtccag gcatctgcca catcccagac cagatatgca cgcggactga
     7561 agtgtccccc gaattgctca tgatgttcat agcggctgcc cacagtcagc gcaagtgcat
     7621 ccgtgagatg ccactcatcc tcagcaaata ccgaccagct tttctgccgg aaagtttcac
     7681 ctgtgctggc aaggacaact ccgtctttca tggacgagct ctgaaactcg ccccccaccg
     7741 taaccagatg agattctccc agaggggtaa gcagtaatga attcaggata aggttcgatt
     7801 ccttaagctc ccgcggctga ccggcaagcc cccatttgtc gcgcttcagt acactgcgta
     7861 cgagctcacg acctttattt tctgtctcgt tccagttcag atacgatttc catgttccga
     7921 aggtgaaagt atgatcatag ccagctgaaa ttttgtttcg ctcatagcgc agggtccggt
     7981 catatccccc cgtcagactc cccagttgcc catcccggtt atcataacgc tgccgggtgg
     8041 tatccatatc aaaccagagc acatcctgcg ccgacgcctt ccagtcaaga cgtgcaccaa
     8101 gattataatt ctgtgactcc gtgggataag gaatacgcgt ggctgctgta tcgctcagtg
     8161 atgtgaccga tgagccctga cgctgttgtg tgctaccgcg tacctgcagg ctgacagaat
     8221 catccacaag gggaccactg ctccagaaat taaactggct gctgttaccc catttgttgc
     8281 tttcctgcag attcagccct gcattgacgg aagagagcca tttgtctgca ttctttctgg
     8341 taatgatatt caccacaccg cccatcgcat cagagccata cagtgtggac atcggccccc
     8401 tgataacctc aatacgctca atggcggcca gagggggcat gaacccggta ttcatggcag
     8461 aaaaaccgtt gggagtcacg tcactgcttc cgccctgacg aacaccatca atcagtatca
     8521 gcgtgtaact ggctggcatt cctcggatgc tgatttccag cccaccggtt ttacccgtac
     8581 cactttcaac atccacaccc tctactgatc tcagagcctc cgccagatcg tggtactggc
     8641 tggactgcaa ttcctcctgg ctaatcacag aaacactggc ggctgcgtta gtcagctttt
     8701 tctcatagcc ggatgcagag acaatcatca catcctctgc agcagctatg ctgctggctg
     8761 aaaatccgag acagggaatg actacggaag ccagagtggt tattcgcata ttactaatct
     8821 ccgatcatgt taaccggcaa gacaatacat aaata
//
LOCUS       DAFGPF010000170         8844 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFGPF010000170 DAFGPF010000000
VERSION     DAFGPF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8844
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.170"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..420)
                     /locus_tag="LSX49_004746"
     CDS             complement(<1..420)
                     /locus_tag="LSX49_004746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171028.1"
                     /translation="MTRVVIALLFLAGCTSQMKYSNVVRIRNVCSSDINVFIPEYVFG
                     GNVIKQHHIYLPVNGIDVLSYFYTENINDGFQYEEAFTVNKDSSGNFDYPFVILSSGR
                     EKKFGKNDLIELSRDISTKDDKKHGVVKYMIDSQNICP"
     gene            complement(413..1831)
                     /locus_tag="LSX49_004747"
     CDS             complement(413..1831)
                     /locus_tag="LSX49_004747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HBL7171029.1"
                     /translation="MGTGYFLVRGDKTTCGGKIIEGADDHTIMGIPQARDMDRVTCGR
                     YPGMFIIVGGVPETDIHGRLMAGTLDSQSSCPCKARFIASMMDDTYETDDGESEAEQH
                     AQSAKKDLTSGSDSSSDDVKLDYRIKLSGNKILTPLNIPDYKEMINGGSTKNTEKIDF
                     TITNKGDEAEGLSLEVLDGNEVIYSERQTGKYFTKGEHAWQWDGYSNQGILDTTKLKS
                     KSLLVRLIALCGDMMIKVDYPLKTSANEEDWVDIEVNKNNKTVNIIWRLAVSDGGIKG
                     SNPKLSPVPYNDLVDLTKNGVEFYWSRNGSRGGGIGESIVTAIGVFKVNVKAEINITP
                     SMRTFSLISSLDPDFQASVSLSGFEKIYYNYGDSYKDIQDELQALLDANNRYKWDSAH
                     EMGHKVLDEYGEGSSPDYSWTHKGTSTLMQKTIPGNVMPAQGEIDVMKYGKYRPDMYT
                     RLVAADEDVQGLIWLSRIKFDD"
     gene            complement(1837..3447)
                     /gene="tssA"
                     /locus_tag="LSX49_004748"
     CDS             complement(1837..3447)
                     /gene="tssA"
                     /locus_tag="LSX49_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HBL7171030.1"
                     /translation="MSELLQKLTRSCFADRDALDVARTQAALWQTWLLPVTADTPVGE
                     DPGYHDDFLRIRDEMNKLSGADTGLICQLAESLLLTQAKDVRIATYYIWARLHRDGER
                     GLAEGLALLAGLVERFGTQLLPSRPASRKMALEWLAGEKMLDSLARYPEVAKEDFANI
                     VAALNQLSVSFTAWPEDQHSPSLMPLINALESRLAQSGGMNAVVPQNSSGVPAPSSPV
                     DAPQVQTITSGRDLLDQAKVLARYLNEQPQGWLSAHRLMKTLRWDTVHELPPDVDGKT
                     RLAPPRTESRNQLKRLYAQQNWTELLEQADLMFSTGVSHFWLDIQWYLHQALAKAGAP
                     WDRWTAVIRQDLALLLERLPGLENLAWNDGTPFADEVTRNWIAQQVMMREDGAWLAGK
                     AAVPTDDATNDVLALEPEALEMADSQGVEAALGWIQTRPGITTARQRLLLRLLMARVA
                     EQYGKNEMALLLLEELDTAAQGITLTQWEPELLFEVKARQLKLLRLRAHRYADKALLN
                     RKMEILLGTLVAIDPVRAAVLCDTQHKD"
     gene            complement(3440..6775)
                     /locus_tag="LSX49_004749"
     CDS             complement(3440..6775)
                     /locus_tag="LSX49_004749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein VasK"
                     /protein_id="HBL7171031.1"
                     /translation="MTVAVVVALCTFIHRKPALLGVEPGSSQQMYWMAGVIAAGVVFL
                     IIMGVYHLLNRHAAVQNFELRRQLAAGDDYRAVTTKKADSRHPAMVELAAFLRDRYGP
                     FWRRKIRLLLVTGEPEQAEAIAPGLTGQHWLEGDHTVLIYGGRPSAEPDVALLTALKK
                     LRRSRPLDGIIWPLTEEQSRQTAQLDKGWRELINGGKRLGFQAPFYLWQVCDNGDYQS
                     GRVLQSVGCLLPEGCTPEQLAAMLEAQTLPLTEQGMSQLLTDNRHDFLLRLAHTLAER
                     GITHWQTVLKPLLAGGAFSSLRLRGLMFSPPLAAVPEAAPHAWLPSPVWAGITGDNAR
                     GRAVGFPWLRTALMSAVCVLAIGGAGMTTSFFANRALVQETSIQTARALDTRLPLAEQ
                     LVALHTLQGELERLQYRIREGAPWYQRFGPERNQQLLAAAFPGYAQAANRLVRDVAVD
                     HLQQQLNAFVALPPNSPQRTATGEQRYKQLKALLMTSRPEKADAAFFSTTLMADGLRY
                     ENIPEGVRQSVLPSLLLTFWMANLPEHPQWKTSPPPELTGAVRKILLRQIGVRNAENT
                     LYQNVLQQVSRNYADMTLADMTGDTLTESLFSTEQTVPGMFTRQAWEGQVREAIEQVV
                     TARREEIDWVLSDRQQDTSADISPDTLRNRLTSRYFTDFAGSWLAFLNSIRWKKEDSL
                     SGILDQLTLMADARQSPLIALTDTIAWQVATGRENRGLSDSLAKSAQELFNGKEKTPQ
                     QSREGDVPAGPLDKTFAPLLRLLGDKSGGGGGDTQLNLQTYLTRVTRVRLKLQQVTNA
                     PDPQEMTQQLAQTVLQGKTVDLTDTRDYGRLIAASLGEEWSGFGQALFVRPVEQSWRQ
                     VLTPAADSLNRQWQRAIVSHWNQDFAGRYPFKASQNDASLPLLAQYLRDDGRINQFIA
                     ANLSGVLKREGRYWVADAMNTQGLTVNPDFIRALNRLRDVADTAFASGDAGIHFELRA
                     KPARDVMKTHLVIDGQELEYFNQKERWQRFNWPDEQWQPGASLSWTSTQAMERILADY
                     RGSWSLIRLLERAQVTPVDSSTFKVVWKAQDGLPLNYLLRVEQGKGPLALLELKNFRL
                     PGQVFLTGRSMKDAEEYGEDADE"
     gene            complement(6832..8046)
                     /locus_tag="LSX49_004750"
     CDS             complement(6832..8046)
                     /locus_tag="LSX49_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171032.1"
                     /translation="MPVRLNTIPDAEPYPVPPARIKWLTALLLMLSVGVALTSLFASD
                     ELAKNGPYFWGLACGVPAFIWSLVASVRWLFFITQYIRTDAWNKRREEVILQETRRGR
                     RALQILSFSVQTALNGDSVAETITAFLARQQVLNTYADLRGEDTVRRSVIPVLTNKPV
                     TGRLSEVFSRLFSDIRLQLTRLPDDFHINVLLEIDAPLSGASVRTIWQDEWQKAGLPE
                     ARLFSAPEPGLAAVDDWLDNHIQEKAVLLVISVRLEPKNPERTAESATALLLANRLTQ
                     TALTPLALLHRPECITDTEMMASGIAQALDWMPVQPDAISGMWTAELDREQRAALLSL
                     NQPFAQEALMYELDAFLGRSGPAAPWLSVAVATLAAIQSQHPQLTLSGVQGGHYSWAT
                     VVSPFVSPQEAS"
     gene            complement(8124..8573)
                     /locus_tag="LSX49_004751"
     CDS             complement(8124..8573)
                     /locus_tag="LSX49_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171033.1"
                     /translation="MQLLSLRTIDGDTLYLKFRNVITGAFLDTPTKSYDFFGDVVLSQ
                     CINGSLIFALEYGSPYIKGCLVTGWENGFKGKNSPEGFCFAERNIPEAVWFGKNNILI
                     IIRNQMDVGTWKGKYIIYDNAKKSGERAYSSDNLPSKDGYIIFALNK"
BASE COUNT         1939 a         2520 c         2214 g         2171 t
ORIGIN      
        1 tgggcaaata ttctgactat ctatcatgta ctttacaacc ccatgcttct tatcgtcttt
       61 tgttgaaatg tccctggata attcaattag atcgtttttc ccaaattttt tttcacgtcc
      121 tgatgataag ataacaaacg gatagtcaaa attacccgag ctatctttat ttacggtgaa
      181 tgcttcttca tattggaaac catcattgat gttttcagta taaaaataag acaaaacatc
      241 aatcccatta acaggtaagt aaatatgatg ttgcttaata acattacctc caaaaacata
      301 ctcaggaata aacacattaa tatctgagga acatacattc ctaatcctga cgacattgga
      361 atacttcatt tgcgaagtac atccggcaag aaataataaa gcaataacta ctctagtcat
      421 caaattttat cctgcttaac cagatcaacc cctgaacatc ttcatctgct gcaaccaatc
      481 gagtatacat gtcaggacga tattttccat atttcattac atcaatctct ccctgagcgg
      541 gcataacatt ccctggtatt gttttttgca taagagtaga tgttccttta tgagtccacg
      601 aataatcagg gctagaaccc tctccatatt catccagtac tttatgcccc atttcatgag
      661 cactatccca tttatatctg ttattagcgt caagaagtgc ctgtaattca tcttgaatat
      721 ccttataact atcaccgtag ttataatata ttttttcaaa tcctgataga ctaacggatg
      781 cctgaaagtc aggatctaat gatgatatca aagaaaaagt tcgcatggat ggagtaatat
      841 ttatctcagc ctttacattt actttaaaaa caccaatcgc tgtaacaata ctttcaccaa
      901 tccccccgcc gcgacttcca tttcgagacc aataaaattc aactccattt ttggtcaggt
      961 caaccaagtc gttataagga actggggata acttaggatt acttcctttt atccctccat
     1021 cactaactgc cagtcgccat attatattta ctgtcttatt gtttttgtta acttctatat
     1081 ctacccaatc ttcctcattc gcagaagttt tcaatggata atcaactttt atcatcatat
     1141 caccacataa agcaatcagt cttacgagta gtgatttact ttttagctta gttgtatcca
     1201 gtatgccttg attactgtag ccatcccatt gccaggcatg ctctccctta gtaaaatatt
     1261 taccggtctg ccgttcacta taaatcactt cattgccatc aagcacttcc agggaaagtc
     1321 cttcagcctc atcgccttta tttgtgatgg taaaatctat tttttctgta ttcttcgtgc
     1381 taccaccgtt tatcatttct ttataatcag gtatattcag tggcgtcagt atcttattac
     1441 ctgataattt aattctgtaa tccagtttta catcatcaga ggatgaatca gaaccagaag
     1501 tcagatcctt tttcgccgac tgcgcatgtt gttccgcttc actttccccg tcatccgtct
     1561 catacgtatc atccatcatt gacgcaataa accgtgcttt acacgggcaa ctgctctgac
     1621 tgtccagcgt ccccgccatc agcctgccgt gaatatctgt ttcaggaacg ccgcccacaa
     1681 taataaacat tcccggatat ctgccgcagg tgacccggtc catatcccgt gcctgcggga
     1741 tacccatgat cgtatggtcg tccgcccctt caataatttt tccaccacag gtggtcttat
     1801 cccccctgac cagaaagtag cctgttccca ttgccatcag tccttatgtt gcgtatcaca
     1861 caataccgct gcccgtaccg gatcgattgc caccagcgtt cccagcagga tttccatttt
     1921 tcggttcagc agggctttat ccgcatagcg gtgcgcccgc agacgcagca gtttcagttg
     1981 tcgggctttt acttcaaaca gcagctctgg ctcccactgt gtcagcgtta ttccctgtgc
     2041 ggcggtatcc agttcttcca gcagcaggag cgccatctcg tttttaccgt actgttccgc
     2101 cacccgtgcc atcagcagtc gcaataacag gcgctgtcgt gccgtggtga tgcccggacg
     2161 ggtctgtatc cagcccagcg ccgcttccac gccctgactg tcagccatct ccagtgcttc
     2221 cggctccagc gccagtacgt catttgtggc gtcgtctgtc ggcacagcgg ctttccccgc
     2281 aagccatgcg ccgtcttccc gcatcatgac ctgctgcgct atccagttgc gcgtcacctc
     2341 atcggcaaac ggcgtgccgt cgttccatgc cagattttcc agccccggca ggcgctccag
     2401 cagcagcgcc aggtcctgac ggataaccgc tgtccatctg tcccacggtg cgcccgcctt
     2461 cgccagcgcc tgatgcagat accactggat atccagccag aaatggctga caccggtgct
     2521 gaacatcagg tcggcctgct ccagcagttc cgtccagttc tgctgggcat acagccgctt
     2581 aagctggttg cgtgattcgg tgcgcggcgg ggccagccgg gttttgccgt ccacgtccgg
     2641 cggcagttca tgcaccgtgt cccagcgcag ggttttcatc agccggtgtg ctgaaagcca
     2701 gccctgcggc tgttcgttca gataacgggc cagcactttc gcctggtcga gtaggtcgcg
     2761 cccggaggtg atggtctgta cctgcggcgc atccaccggg gaagacggtg ccggaacgcc
     2821 gctgctgttt tgcggcacca ccgcgttcat cccgcccgac tgcgccagac gtgattccag
     2881 cgcgttaatc agcggcatca gggaggggga atgctggtct tcgggccatg cagtgaagga
     2941 aaccgacagt tgattaagag cggcaacaat gttcgcaaaa tcctcttttg ccacctccgg
     3001 gtagcgggca aggctgtcga gcatcttttc ccccgccagc cactccagcg ccatttttcg
     3061 gcttgccggt cgcgagggca gcagttgcgt accgaagcgt tccaccagcc cggctaacag
     3121 cgccagtcct tcagccagtc cgcgctcacc gtcgcggtgc agtcgcgccc agatgtagta
     3181 agtggcgatg cgcacgtctt tggcctgcgt cagcagcagg gattcggcaa gctggcagat
     3241 aaggccggta tcggcaccgg acagtttgtt catttcgtcg cggatacgca ggaaatcgtc
     3301 gtggtagccg gggtcttccc cgaccggcgt gtctgccgtc accggcagca gccatgtctg
     3361 ccacagcgcc gcctgtgttc gcgccacatc cagtgcatcc cggtcggcaa aacagctacg
     3421 ggtcagcttt tgcaacagtt cactcatcgg cgtcttcccc atactcttcc gcatccttca
     3481 tactcctgcc ggtcagaaat acctgtcccg gcaggcggaa gtttttcagt tccagcagcg
     3541 ccagcggccc tttaccctgt tcaacccgca gcaggtaatt cagtggcagg ccgtcctgcg
     3601 ctttccacac cactttaaag gtgctgctgt cgaccggtgt tacctgcgcc cgttccagca
     3661 ggcgaataag gctccagctt ccccggtaat ccgccagtat gcgttccatc gcctgtgtgc
     3721 tggtccagct cagcgatgcg ccgggttgcc actgttcatc cggccagtta aaacgctgcc
     3781 agcgttcttt ctggttgaaa tactccagtt cctgcccgtc aatcaccaga tgcgttttca
     3841 tcacgtcacg cgccggtttt gcccgcagtt cgaaatgtat tccggcatcg ccgctggcaa
     3901 aggcggtatc ggccacatcg cgcaggcggt tcagggcgcg gataaagtcc gggttgaccg
     3961 tcagcccctg cgtgttcatg gcgtcagcca cccagtagcg gccttcacgt ttcagaacac
     4021 cggaaaggtt ggcggcgata aactggttga tgcgtccgtc atcgcgcagg tactgcgcca
     4081 gcaagggaag agaggcatcg ttctgtgagg ctttgaacgg atagcggcca gcgaagtcct
     4141 gattccagtg actgacaatc gcccgttgcc actggcggtt caggctgtcc gctgcgggcg
     4201 tcagcacctg ccgccacgac tgttccaccg ggcggacgaa cagcgcctga ccgaagccac
     4261 tccattcttc gcccagactg gcggcgatta accgcccgta gtcgcgggtg tcggtgaggt
     4321 caacggtttt gccctgtaaa accgtctgcg ccagttgctg ggtcatctcc tgcgggtcgg
     4381 gggcgttggt cacctgttgc agtttgaggc gtacgcgggt gacgcgggtc agatacgttt
     4441 gcaggttgag ttgcgtatca ccaccaccgc ctcctgactt atcgcccagc aaccgcagca
     4501 gcggcgcgaa ggttttatcc agcggcccgg caggcacgtc gccttcacgg gattgctgcg
     4561 gcgttttctc cttgccgtta aacagttcct gtgccgattt cgccagcgag tctgacaggc
     4621 cacgattttc cctgcctgtt gccacctgcc acgcaatagt gtctgtcagt gcaatcagtg
     4681 gcgactgacg ggcatcggcc atcagcgtca gctggtcgag aatgccggag agcgagtctt
     4741 cctttttcca gcgaatgctg ttgagaaacg ccagccagct tccggcaaag tcggtaaagt
     4801 agcgtgaggt gaggcggtta cgcagcgtat ccggcgagat atcagcagag gtatcctgct
     4861 ggcggtcgct gagtacccag tcgatttcct cgcgccgcgc cgtcaccacc tgctcgatag
     4921 cttccctgac ctgtccttcc catgcctgac gggtgaacat ccccggcacc gtctgttccg
     4981 tactgaaaag agattcagtg agggtatccc cggtcatgtc cgccagcgtc atatcggcgt
     5041 agttgcggga cacctgttgc agcacgttct ggtagagggt gttttcggca ttacgcacac
     5101 caatctggcg cagcaggatt ttacgcaccg cgccggtcag ttccggtggc ggtgaggttt
     5161 tccactgcgg gtgttccggc aggttcgcca tccagaaggt cagcagcagt gacggcaaca
     5221 cgctctgccg cacgccttcc gggatatttt catagcgcag gccgtctgcc atcagcgtgg
     5281 tactgaaaaa ggcagcgtcg gccttttccg ggcgggaagt catcagcaat gccttaagct
     5341 gcttatagcg ttgttcaccg gtggcggtac gctgaggact gttgggcggc agggcgacaa
     5401 aggcgttcag ttgctgttgc agatggtcaa cggccacgtc gcgcaccagc cggtttgccg
     5461 cctgcgcata gccgggaaag gcggcggcga gcagttgctg gttacgttca gggccaaaac
     5521 gctgatacca cggcgcacct tcgcggatac ggtattgcag gcgttccagt tcgccctgca
     5581 gggtatgcag cgccaccagt tgttctgcca gcggcaggcg ggtatcgagc gcccgcgccg
     5641 tctggatgct ggtttcctga acaagtgcgc ggttggcgaa gaacgaggtc gtcattccgg
     5701 ccccccctat cgccagcacg cagacagcgg acatcagtgc ggtacgcagc cacggaaagc
     5761 ccaccgcgcg gccccgcgcg ttatcgccgg tgatgcctgc ccagaccggc gacggcagcc
     5821 acgcatgagg tgcggcctcc ggtacggcgg caagcggcgg gctgaacatc aggccgcgca
     5881 ggcgcaggga agaaaatgcg ccgcctgcca gcagcggttt caggacggtc tgccagtggg
     5941 tgataccccg ctctgcaagg gtatgggcca gacgcagcag aaaatcatgg cggttatcgg
     6001 tcagcagctg cgacatgccc tgttccgtca gcggtagggt ctgtgcttcc agcattgcag
     6061 ccagttgttc cggggtacag ccttccggca gcaggcagcc gacgctttgc aggacgcgcc
     6121 cggactgata atcaccgttg tcacagacct gccacaaata gaatggggcc tgaaaaccga
     6181 gtcgcttacc gccgtttatc agttcgcgcc agcctttgtc gagttgcgct gtctggcggc
     6241 tctgttcttc tgtcagcggc cagatgatgc cgtccagcgg acggctgcgg cgcagttttt
     6301 ttaaggcggt cagtagcgcg acatcaggct ccgctgatgg cctgccgccg tatatcagca
     6361 ccgtgtggtc gccctccagc cagtgttgcc cggtcagccc cggcgcgatg gcctctgcct
     6421 gttcaggctc gccggtcacc agcagcaggc ggattttacg ccgccagaat gggccgtagc
     6481 ggtcgcgcag gaaggcggcg agttccacca ttgccggatg acggctgtcg gctttctttg
     6541 tcgtcaccgc acgatagtca tctccggcgg caagctgtct gcggagttca aagttctgca
     6601 cggcagcgtg gcggttcagc agatgataaa cccccatgat aatcagaaag accacgcctg
     6661 cggcaatcac gccagccatc cagtacattt gctgtgagct acccggttca acgcccagca
     6721 atgccggttt acggtgaata aacgtgcaaa gcgcaaccac aacagccacg gtcatgacga
     6781 tggcaggccc tgaaaccgaa cggggccgga gacggtttaa tcccggaacc actatgatgc
     6841 ctcctgaggg gaaacgaatg gcgacaccac ggtcgcccat gaataatgcc cgccctgaac
     6901 gccgctgagc gtcagttggg ggtgttgtga ttgtattgcc gccagcgttg ccacagcgac
     6961 ggacagccac ggcgcagccg gtccggagcg ccccagaaag gcatccagct cgtacatcag
     7021 ggcttcctga gcaaacggct ggttcaggct taacaacgcg gcacgctgtt ccctgtccag
     7081 ttcggcagtc cacataccgg atatggcatc tggctgcacc ggcatccagt ccagcgcctg
     7141 tgcaatgcct gacgccatca tctctgtatc agtgatacat tcaggacgat gcagcagggc
     7201 cagcggcgtc agcgcggttt gcgtcaaccg gtttgccagc aacagcgcgg tggcggattc
     7261 tgccgtccgt tccgggttct tcggttccag acgcacggaa atcaccagca gtacggcctt
     7321 ttcctgaatg tggttgtcca gccagtcgtc cacggcggcc agccccggct ccggggctga
     7381 aaacagacgg gcttccggga gtccggcttt ttgccattcg tcctgccaga tagttctcac
     7441 ggaggcccct gaaagcggcg catcaatttc cagtagtacg ttgatatgaa aatcatcggg
     7501 tagccgcgtc agttgcagcc tgatatcgct gaacagacgg gaaaaaactt cggatagacg
     7561 tccggtaacc ggtttattgg ttaatacagg gatgacgctg cgacgcacag tatcttctcc
     7621 gcgcaagtca gcgtaggtat tcaacacctg ctgacgtgcc agaaatgctg ttatagtttc
     7681 tgcaacggaa tcaccattca gcgcggtttg tacggaaaaa ctgagtatct gcaacgcccg
     7741 tcgtccccgg cgcgtttcct gcaaaatcac ctcttcccgg cgcttattcc aggcatcagt
     7801 ccgaatgtac tgcgtgataa aaaacagcca gcgaactgaa gcaaccagtg accagataaa
     7861 ggcaggcaca ccacaggcca gcccccagaa atacgggccg ttttttgcca gttcatcgct
     7921 ggcgaataat gaagtcaggg ccacaccgac agacagcatc agtaataaag ctgtcagcca
     7981 cttaattcgg gctggcggta cgggataggg ttctgcgtcg ggaatggtat taagtcggac
     8041 tggcatcagt acatcccttt attttgcatt atcgaccaga agttaataac caagtgaaat
     8101 ttaaagttat gtatagagtc attttattta tttaatgcaa aaattatgta accatctttt
     8161 gatggtagat tatctgatga gtatgctctt tctcctgact ttttcgcatt atcatagata
     8221 atatatttcc ctttccatgt cccaacatcc atttggtttc ggatgataat taaaatattg
     8281 ttttttccaa accataccgc ttcgggaata tttctctctg cgaaacaaaa gccttcagga
     8341 gagttcttac ctttaaaccc attttcccaa ccagttacca gacaaccttt tatatatgga
     8401 gaaccatatt ccagcgcaaa gataagagaa ccatttatgc actgagaaag aaccacatct
     8461 ccaaaaaaat cataactttt agttggagta tctaaaaagg ccccggtgat aacatttctg
     8521 aattttagat ataatgtatc accgtcaatg gttctaaggg aaagcaactg cacactttca
     8581 tttttttcaa ttgacaggtt ttcacgattt taatcttatc gcctgaaaaa caggggaaag
     8641 aaaaaaaaca aagtaatatt aacataatgc gcatactatc ttcctattcc ctccattagt
     8701 atttgtatgt tatcaggatc tttagccagt ttttcagcgc aaggttttat aacagaatag
     8761 tatgcttcat ctgttccacg atatgtccga tatgcctcct caattgttgc ttctttatct
     8821 atccagtatt gcaaatactc tgtg
//
LOCUS       DAFGPF010000171         8601 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFGPF010000171 DAFGPF010000000
VERSION     DAFGPF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8601
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.171"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            214..1089
                     /gene="rluB"
                     /locus_tag="LSX49_004752"
     CDS             214..1089
                     /gene="rluB"
                     /locus_tag="LSX49_004752"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HBL7171034.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEI
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QVSGGRRSGGRNNNG"
     gene            1259..2281
                     /locus_tag="LSX49_004753"
     CDS             1259..2281
                     /locus_tag="LSX49_004753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171035.1"
                     /translation="MIRYSGIFLSLLMLSGCATEALKNEQAETVITAGNKAVAANASF
                     FKQYYASRENFLVNFYATNPDCALRPDYETIMENNTNKESLCLQSEKGGKTSYKDITK
                     IQLATTEKQKLLASLEVVNSMSSYVELLTVGMDVEDSKQIILLNQALDHANNAQKLLG
                     LSEGEELTKSVVAVKDLVQYFNGLYKEKIKSENVGKTVGSDWPRLQRNLQDLLDDIAT
                     KQQQMDRNNYANISNNFYYYNKAQANTKNIEFKTLKSRQEFLSAVINLNESRLRSSDP
                     AAPAIQAINAFMDKGNHLQDLYSNKSLSKADLERRNEILRSQVISGLQASEELAKLLI
                     ASGVML"
     gene            2291..2599
                     /locus_tag="LSX49_004754"
     CDS             2291..2599
                     /locus_tag="LSX49_004754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171036.1"
                     /translation="MNDVQNRRILALLNMLYYALGNRTTCDICHKYFILVLSVMNNLT
                     INYGSQTSPELTGISYEDANDLITELILFIEDVNADNDMEYPAHLNKIQALLNFAVAN
                     "
     gene            complement(2656..3246)
                     /gene="cobO"
                     /locus_tag="LSX49_004755"
     CDS             complement(2656..3246)
                     /gene="cobO"
                     /locus_tag="LSX49_004755"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HBL7171037.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEDVIQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPIKHAFDAGVKAQIGIDY"
     gene            complement(3243..4001)
                     /locus_tag="LSX49_004756"
     CDS             complement(3243..4001)
                     /locus_tag="LSX49_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HBL7171038.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSEDCQQLAQRIAVNYPRLDGVLHNAGL
                     LGDVCPMSEQDPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
     gene            4221..5270
                     /gene="sohB"
                     /locus_tag="LSX49_004757"
     CDS             4221..5270
                     /gene="sohB"
                     /locus_tag="LSX49_004757"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HBL7171039.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDTHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVVTDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            complement(5306..5557)
                     /locus_tag="LSX49_004758"
     CDS             complement(5306..5557)
                     /locus_tag="LSX49_004758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HBL7171040.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            5937..8534
                     /gene="topA"
                     /locus_tag="LSX49_004759"
     CDS             5937..8534
                     /gene="topA"
                     /locus_tag="LSX49_004759"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBL7171041.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSTA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
BASE COUNT         2319 a         1916 c         2223 g         2143 t
ORIGIN      
        1 ataaagctga tgttaatcga aacaagcttt aaccataaag atagtgtagt atgttgcgcc
       61 tcaaagccag gccagttaaa acgtcgagtc gtttacttaa ggcctgaaga gttcaaacag
      121 actttactat cagtgagtca gatgtaagtt ctgactcatt gttgcacaaa agcatatcag
      181 acgcctggga aggcgacacc aaaaggaagc tctatgagcg aaaagctaca gaaagtgctg
      241 gcgcgtgccg gccacggttc tcgccgtgaa atcgaatcta ttattgaagc cggtcgtgtg
      301 agtgttgatg gcaaaattgc taaactcggc gatcgcgttg aaattacccc tggactgaaa
      361 atccgtatcg atggtcacct gatttcggta cgtgagtccg ctgaacaaat ttgtcgcgtt
      421 ctggcctatt acaaaccgga aggtgagttg tgtacccgta acgatccgga agggcgtcca
      481 acggtgtttg accgtctgcc aaagctgcgt ggcgcacgct ggattgccgt aggtcgtctg
      541 gacgttaaca cctgtggtct gttgttgttc accaccgacg gtgaactggc aaaccgttta
      601 atgcatccaa gccgtgaagt tgaacgtgaa tatgccgtgc gtgtatttgg tcaggttgac
      661 gacgcgaaac tgcgtgattt gagtcgtggc gtgcagctgg aagatggtcc ggcagccttt
      721 aaaaccatca agttcagcgg cggcgaaggg atcaaccagt ggtacaacgt tactctgacc
      781 gaaggccgta accgtgaagt tcgtcgtctg tgggaagcgg ttggtgtgca ggtgagccgc
      841 ctgattcgcg ttcgttacgg tgatatccca ctgccaaaag gtctgccacg cggtggctgg
      901 acggagctgg acctcgccca gactaactat ctgcgcgaac tggtggaact accgccagaa
      961 accagctcta aagtcgctgt agaaaaagac cgtcgtcgta tgaaggcgaa tcagattcgt
     1021 cgtgcggtga aacgtcacag tcaggtgagc ggcggtcgtc gttctggcgg acgtaataat
     1081 aacggttaat ttaagttaag tattaaataa aggccctgcg gggccttttc ttcatttgaa
     1141 gtatgataaa tagtcgcagt attttaattt aatttcatac ttgcttatga ataatgccag
     1201 ggaatagcca cattactatt taattatctg agataaactc aacgtcaaga ggtgggttat
     1261 gattagatat agtggaatat ttctatcgct gttaatgctt tcaggttgtg caaccgaagc
     1321 attgaagaat gaacaagctg aaactgttat tactgcgggt aacaaggcgg ttgcggcgaa
     1381 tgcaagtttc tttaaacaat actatgcttc tcgtgaaaac tttcttgtta atttttatgc
     1441 gactaatccg gattgtgcat tgcgacctga ttacgaaacg attatggaaa ataatactaa
     1501 taaagagtcc ttatgtttgc aatcagagaa agggggcaaa acatcgtata aagacattac
     1561 taaaattcaa ttggcaacaa cagaaaaaca aaaactactg gcttcacttg aggtcgttaa
     1621 cagtatgagt tcctatgtgg agttgttgac ggtgggtatg gatgttgagg atagtaaaca
     1681 aattatatta cttaatcagg cgctcgatca cgcaaacaac gcccaaaaac tacttggcct
     1741 ttcagaaggt gaagaattga ctaagtcagt tgtggctgtt aaagatttag ttcaatattt
     1801 caatggatta tacaaagaga agattaaatc agaaaatgtt ggtaaaacgg taggtagtga
     1861 ctggcctcga cttcaaagaa atttacaaga tttactcgat gatatagcaa cgaaacagca
     1921 gcaaatggat cggaataatt atgcgaacat cagtaataat ttttattact acaataaggc
     1981 ccaggcaaat actaaaaata tagagtttaa gacattaaag agcaggcagg aatttttgag
     2041 tgcagtaatt aatcttaatg aaagcagatt gcgttcatct gatccggcgg ctccagcaat
     2101 acaagctatt aatgccttca tggataaagg aaatcatcta caagatttat actctaataa
     2161 atctctttca aaagcggatt tagagcgtag aaatgagatc cttcgttctc aagttattag
     2221 tggtctacag gcgtcagagg agctggcaaa acttcttatt gccagcggag ttatgttata
     2281 ggaggtcatt atgaacgatg tgcaaaatcg acgaatactg gcattgctca atatgctgta
     2341 ctatgcctta ggaaaccgaa caacctgcga tatatgtcac aaatatttta ttctggtttt
     2401 gtcagtaatg aataatctga caattaatta tggctcgcaa acgtcaccag aactgacggg
     2461 tattagttat gaagatgcta atgatttgat cactgaatta atactgttta ttgaagacgt
     2521 caatgcggat aatgatatgg aatatcccgc acacttgaat aaaattcaag ctcttcttaa
     2581 ttttgccgtg gctaattaag ccattcagta tctaaaatta gcacctcaag aggcgaactt
     2641 ttgaggtgct ttcacttagt aatcaatccc tatctgcgct tttacaccgg catcaaacgc
     2701 atgtttgatg gggcgcagct cacttaccgt atccgccagt tcaagaatat cccgatgaca
     2761 gcctcgaccc gtgataatca ccgtctgttg atgtggacgt tcatttaacg cctgaatcac
     2821 gtcttccagt ggcaaatagt catacgctac catatatgtc agttcatcga gcaaaaccat
     2881 atccagtgag gaatcagcca gcatccgctt tgcatgttgc cagacttcgc ggcaggcggc
     2941 ggtatcggac tctcggtttt gtgtatccca ggtaaagccc gttgccatta cctgaaactc
     3001 aacgccgtgt ggctccagca gatttcgttc accattaggc caggtgcctt taataaactg
     3061 cacgacgccc actttttttc cgtgaccaac tgcgcgtgtt gccgtaccaa atgccgcggt
     3121 ggttttgcct tttccattgc cggtaaagac gatgataata ccgcgttcat cctgggcctg
     3181 ggccacacga gcatctactt tttctttcac tcgctgctga cgctgttggt agcgttcatc
     3241 actcattggg aaattcctgg tttacggccc ggttgggcgt caaaggtcat gccggtttta
     3301 cggcggctgt catcgcccat cagccagagg tagagcggca tgatatcagc gggggtttta
     3361 agtttctgtg gatcttcggt cgggaaggca ctggcccgca ttgcggtgcg cgtaccgcct
     3421 gggttaatgc agttgacacg caggcgctgc tgatattcat cggccagtac ctgcatcatc
     3481 ccttcggtgg caaatttcga cgctgcatat gcgccccagt ttgcacgccc ctgacgtcca
     3541 acgcttgatg aggtaaagac cagtgaaccg gcgtcggatt tgagtaataa aggaagcagt
     3601 gcctgggtga gcataaaggt ggcattaacg ttgacctgca tgacgtcctg ccagacttgc
     3661 ggatcttgtt cgctcattgg gcaaacatcg ccgagcaatc cggcattatg caaaacacca
     3721 tccagacgcg gataattaac ggcaatgcgc tgtgccagtt gttggcaatc ttcggacgtg
     3781 caggttagca aatcgagaat aaaccactgt ggctgacgtc cagtttcttc gtttatgtgg
     3841 ctggctacct gacgtaattt ttcttcatta cggcccaaaa gaatcactgt cgcaccatag
     3901 cgtgcatacg tcatcgctgc ttcacgacca attccatcgc tggctcccgt caccagaata
     3961 atgcgatcat tgagtaaatc ttgttttggc tggtaatgca tggctactcc tcaacgacgt
     4021 tgtctgtcgc gctgccagtg tactttatga ctttggggct ttatgcctga aacagaaggg
     4081 catttcaatc agcctggggc gataacaccg caaaatggat actttgtcat actttcgctg
     4141 caataacatc tctgcgagac ggctaaacat gcctgttgta aactgtgagc caaagcgttg
     4201 tttaaccaag gtggggactc gtggaattgt tgtctgaata tggtttgttt ttggcgaaaa
     4261 tcgttaccgt tgtgctagcg attgcggcga ttgccgccat tattgtcaat gttgctcaac
     4321 gtaataaacg ccagcgtggc gagttacgag tcaacaatct cagcgaacag tataaggaga
     4381 tgaaagaaga actggccgcg gcgctgatgg acactcatca gcaaaaacag tggcacaaag
     4441 cgcagaagaa aaagcacaag caagaagcga aagccgcaaa agcgaaagct aaactgggcg
     4501 aggtggtaac tgacagtaaa ccccgcgtct gggtgctgga ttttaaaggc agcatggacg
     4561 cccatgaagt gaactctcta cgtgaagaga taacggcggt actcgcagca ttcaaaccgc
     4621 aggatcaggt tgtgctccgt ctggaaagcc caggtggcat ggtgcatggt tacgggttgg
     4681 cggcttcgca gttgcagcgt ctgcgtgata aaaacattcc tttaactgtt acggtagaca
     4741 aagtcgctgc cagcggcggt tacatgatgg cctgtgtggc ggacaaaatt gtttccgcac
     4801 cgtttgctat tgtgggttcc attggggtgg tggcgcaaat gcccaacttt aaccgcttcc
     4861 tgaaaagcaa agatattgat atcgaactgc acaccgccgg gcagtataag cgcacgctga
     4921 cgttgctggg tgaaaatacc gaagaagggc gggagaaatt ccgcgaagag ttgaacgaaa
     4981 cgcatcagtt atttaaagat tttgtgaagc gtatgcgtcc gtctctggat attgaacagg
     5041 tggcaacggg tgaacactgg tacggacaac aggcagtaga gaaaggcctg gttgatgaaa
     5101 tcaacaccag tgatgaagtt attcttagcc tgatggaagg ccgggaagtg gtcaatgtac
     5161 gctatatgca gcgtaaacga ctcattgacc gattcaccgg cagcgcggca gagagcgccg
     5221 atcgattgtt gttacgctgg tggcagcgtg ggcaaaagcc gttgatgtaa aagacaaacg
     5281 cgaggataag acctcgcgtt ttgctttaat caaccaggtg atatttttct gaaagcacat
     5341 gggccaggtg tttgaacata ttaaacaccg cggtgctttt ggcagttggt aatccttgtt
     5401 catctaaaaa gtagtcgccg gtaaatacca gcacgccatt acgctgcgtg acgccggtgg
     5461 cttcaatccc tgcgagcgta tcctcatgct cacgaatgat tttgttggcc tctttcaaca
     5521 gcgtttcgcg gtcgatgggt tgagtctctt tgttcattat ttactcctta aacaaggaca
     5581 ttagtctacg ccaggcatgg cttgcagaca aatataccac gctggtggca agagcgcctt
     5641 actggcaact ttggattttg catgctaata aagttgcgta tcggatttta tcaggtacag
     5701 tgtgacgctt tcgtcaatct ggcaatagat ttgcttgaca ttcgaccaaa attccgtcgt
     5761 gctatagcgc ctgtaggcca agacctgtta actcagtcac ctgaattttc gtgagcagag
     5821 tcacgacaag gggttgatat ccgcagagag cgagtccata tcggtaactc gttgccagtg
     5881 gaaggtttat caacgtgcga cgcattcctg gaagaatcaa attaggtaag gtgaatatgg
     5941 gtaaagctct tgtcatcgtt gagtccccgg caaaagccaa aacgatcaac aagtatctgg
     6001 gtagtgacta cgtggtgaaa tccagcgtcg gtcacatccg cgatttgccg accagtggct
     6061 caactgccaa aaagagtgcc gactctacct ccaccaagac ggctaaaaag cctaaaaagg
     6121 atgaacgtgg cgctctcgtc aaccgtatgg gggttgaccc gtggcacaat tgggaggcgc
     6181 actatgaagt gttgcctggt aaagagaagg tcgtctctga actgaaacaa ctggctgaaa
     6241 aagccgacca catctatctc gcaaccgacc ttgaccgcga aggggaagcc attgcatggc
     6301 acctgcggga agtgattggt ggtgatgatg cgcgctatag ccgagtggtg tttaacgaaa
     6361 ttactaaaaa cgcgatccgc caggcattta acaaaccggg tgagctgaat attgatcgtg
     6421 ttaatgccca gcaggcgcgt cgctttatgg accgcgtggt ggggtatatg gtttcgccgc
     6481 ttctatggaa aaagatcgct cgtggtctgt ctgccggtcg tgtgcagtcg gtggcggtcc
     6541 gcctggtggt cgagcgtgag cgtgaaatta aagcgttcgt accggaagag ttctgggaag
     6601 tcgatgccag cacgaccacg ccatctggtg aagcgttggc gttgcaggtg actcatcaga
     6661 acgacaaacc gttccgtccg gtcaacaaag aacaaactca ggctgcggta agtctgctgg
     6721 aaaaagcgcg ctacagcgtg ctggaacgtg aagacaaacc gacaaccagt aaacctggcg
     6781 ctccttttat tacctctacg ctgcaacaag ctgccagcac ccgtcttggt tttggcgtga
     6841 aaaaaaccat gatgatggcg cagcgtttgt atgaagcagg ctatatcact tacatgcgta
     6901 ccgactccac caacctgagt caggacgcgg taaatatggt tcgcggttat atcagcgata
     6961 attttggtaa gaaatatctg ccggaaagtc cgaatcagta cgccagcaaa gaaaactcac
     7021 aggaagcgca cgaagcgatt cgtccttctg acgtcaatgt gatggcggaa tcgttgaagg
     7081 atatggaagc agatgcgcag aaactgtacc agttaatctg gcgtcagttc gtagcctgcc
     7141 agatgacccc agcgaaatat gactccacga cgctgaccgt tggtgcgggc gatttccgcc
     7201 tgaaagcacg cggtcgtatt ttgcgctttg atggctggac gaaagtgatg cctgcactgc
     7261 gtaaaggcga tgaagatcgt atcttaccgg cagtcgataa aggcgatgct ctgacgctcg
     7321 ttgaactgac accagcccag cactttacca agcctccagc ccgtttcagt gaagcatcgc
     7381 tggtcaaaga gctggaaaaa cgcggtatcg gtcgtccttc tacctatgcg tcgatcattt
     7441 cgaccattca ggatcgtggc tatgtgcgag tagaaaatcg tcgtttctat gcggaaaaaa
     7501 tgggcgaaat cgtcaccgat cgcctggaag agaatttccg cgagttaatg aactacgact
     7561 tcaccgcgca gatggaaaac agcctcgacc aggtggcaaa tcacgaagca gagtggaaag
     7621 ctgtactgga tcacttcttc tcggatttca cccagcagtt agataaagct gaaaaagatc
     7681 cggaagaggg tggtatgcgc ccgaaccaga tggttctgac cagcattgac tgcccgactt
     7741 gtggtcgcaa aatggggatt cgcacagcga gcaccggggt attccttggc tgttctggct
     7801 atgcgctgcc gccgaaagag cgttgcaaaa ccaccattaa cctggtgccg gaaaacgaag
     7861 tgctgaacgt gctggaaggt gaagacgctg aaaccaatgc gttgcgcgca aaacgtcgtt
     7921 gcccgaaatg tggcacggcg atggacagct atctcatcga tccgaaacgt aagttgcatg
     7981 tctgtggtaa taacccaacc tgcgacggtt acgagatcga agagggtgaa ttccgcatta
     8041 aaggttatga cggcccgatc gttgagtgtg aaaaatgtgg ctctgaaatg cacctgaaaa
     8101 tggggcgttt cggtaaatac atggcctgca ccaacgaaga gtgtaaaaac acacgtaaga
     8161 ttttacgtaa cggcgaagtg gcaccaccga aagaagatcc ggtgccatta ccggagctgc
     8221 cgtgcgaaaa atcagatgcc tatttcgtgt tgcgtgacgg tgctgccggt gtgttcctgg
     8281 cggccaatac cttcccgaaa tcgcgtgaaa cgcgtgcgcc tctggtggag gagctttatc
     8341 gcttccgcga ccgtctgccg gaaaaactgc gttatctggc cgatgcgcca cagcaggatc
     8401 cggaaggtaa taagaccatg gttcgcttta gccgtaaaac caaacagcaa tatgtctctt
     8461 cggaaaaaga cggaaaggcg actggttggt cagcatttta tgttgatggc aaatgggttg
     8521 aagggaaaaa ataaccttta attccgtctg gtttttataa acaaagggtc gcgaaagcgg
     8581 ccctttttta ttgcatatta t
//
LOCUS       DAFGPF010000172         8575 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFGPF010000172 DAFGPF010000000
VERSION     DAFGPF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8575
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.172"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1203..1889
                     /locus_tag="LSX49_004760"
                     /pseudo
     CDS             1203..1889
                     /locus_tag="LSX49_004760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554952.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            2221..3096
                     /locus_tag="LSX49_004761"
     CDS             2221..3096
                     /locus_tag="LSX49_004761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChaN family lipoprotein"
                     /protein_id="HBL7171042.1"
                     /translation="MRKFILISMITLASVSLGACRQNVTIKQDAPGQKAFLTDGQIYD
                     LHSGKIISSSELLADLATAQHLIIGEKHDNAEHHQIELWLIQNLLIQRPQGSVLLEML
                     TSEQQPRVNQVKCWLKDNPVVRDSRVQELLNWQKGWSWEMYGDIVMQLLRGPYPLLNA
                     NIGREQILALYKKNEFPKGKKSTAPVVQEALRETIISMHEGNLESQQLTSMLSIQQQR
                     DRYMARQLLSAPVPSLLIAGGYHASKSMGVPLHMEDLATGTHPVVLMLAEKGMNITVD
                     HADYVWFVAPDTTKR"
     gene            3104..3880
                     /locus_tag="LSX49_004762"
     CDS             3104..3880
                     /locus_tag="LSX49_004762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HBL7171043.1"
                     /translation="MMNILHFSQSVKWSSWFICSLLLHGLIFLAFIWRFSEVQPAMSP
                     APAIMLQWAEIIEAPSSPLSLPVGIAQQESAVTEEKQQTEDRQQRPVTEDSDATIEIT
                     RKKKSSDGEKKKTRPPRKIKAQTSDSNPTAVSSNAAPQALVESSRIAAPFNSDSTKRD
                     NSEASWESRVKGHLNRYKRYPGDARKRARTGTAVVTFTVNTEGTIVSSFLEISSGTFS
                     LDREAIAVLERAQPLPKPPPEILEGGLFKVKMPITFKLKE"
     gene            4049..6310
                     /locus_tag="LSX49_004763"
     CDS             4049..6310
                     /locus_tag="LSX49_004763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBL7171044.1"
                     /translation="MNVIKLAIGSGILLLSCGAYSQSISEKTNSDKKGAAEFSPLSVS
                     VGKTTSEQEALEKTGATSSRTTDKNLQSLDATVRSMPGTYTQIDPGQGAISVNIRGMS
                     GFGRVNTMVDGITQSFYGTSTSGTTTHGSTNNMAGVLIDPNLLVAVDVTRGDSSGSEG
                     INALAGSANMRTIGVDDVIFNGNTYGLRSRFSVGSNGLGRSGMIALGGKSDAFTDTGS
                     IGVMAAVSGSSVYSNFSNGSGINSKEFGYDKYMKQNPKSQLYKMDIRPDEFNSFELSA
                     RTYENKFTRRDITSDDYYIKYHYTPFSELIDFNVTASTSRGNQKYRDGSLYTFYKTSA
                     QNRSDALDINNTSRFTVADNDLEFMLGSKLMRTRYDRTIHSAAGDPKANQESIENNPF
                     APSGQQDISALYTGLKVTRGIWEADFNLNYTRNRITGYKPACDSRVICVPQGSYDIDD
                     KEGGFNPSVQLSAQVTPWLQPFIGYSKSMRAPNIQEMFFSNSGGASMNPFLKPERAET
                     WQAGFNIDTRDLLVEQDALRFKALAYRSRIQNYIYSESYLVCSGGRKCSLPEVIGNGW
                     EGISDEYSDNMYIYVNSASDVIAKGFELEMDYDAGFAFGRLSFSQQQTDQPTSIASTH
                     FGAGDITELPRKYMTLDTGVRFFDNALTLGTIIKYTGKARRLSPDFEQDEHTGAIIKQ
                     DLPQIPTIIDLYGTYEYNRNLTLKLSVQNLMNRDYSEALNKLNMMPGLGDETHPANSA
                     RGRTWIFGGDIRF"
     gene            6379..7554
                     /gene="senB"
                     /locus_tag="LSX49_004764"
     CDS             6379..7554
                     /gene="senB"
                     /locus_tag="LSX49_004764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterotoxin production-related protein TieB"
                     /protein_id="HBL7171045.1"
                     /translation="MNIFTLSKAPLYLLISLFLPTMAMAIDPPERELSRFALKTNYLQ
                     SPDEGVYELAFDNASKKVFAAVTDRVNREANKGYLYSFNSDSLKVENKYTMPYRAFSL
                     AINQDKHQLYIGHTQSASLRISMFDTPTGKLVRTSDRLSFKAANAADSRFEHFRHMVY
                     SQDSDTLFVSYSNMLKTAEGMKPLHKLLMLDGTTLALKGEVKDAYKGTAYGLTMDEKT
                     QKIYVGGRDYINEIDAKNQTLLRTIPLKDPRPQITSVQNLAVDSASDRAFVVVFDHDD
                     RSGTKDGLYIFDLRDGKQLGYVHTGAGANAVKYNPKYNELYVTNFTSGTISVVDATKY
                     SITREFNMPVYPNQMVLSDDMDTLYIGIKEGFNRDWDPDVFVEGAKERILSIDLKKS"
     gene            complement(8077..8382)
                     /locus_tag="LSX49_004765"
                     /pseudo
     CDS             complement(8077..8382)
                     /locus_tag="LSX49_004765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198547.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
     gene            8408..>8575
                     /locus_tag="LSX49_004766"
     CDS             8408..>8575
                     /locus_tag="LSX49_004766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL7171046.1"
                     /translation="MTKNTRFSPEVRQRAVRMVLESQGEYDSQWATICSIAPKIGCTP
                     ETLRVWVRQHER"
BASE COUNT         2432 a         1933 c         1989 g         2221 t
ORIGIN      
        1 tgtttataat ttattggttg tatgttaaat ctatcataag tctaatgatt aaaatggtta
       61 gtggtgtcag gattagtgaa aataaaggat gtaatatgct attctttctc tgtaagtact
      121 tgagaatact aaaccatagt acaagaatga ttatgtacat gtagtgagaa ttggaaaaca
      181 tagtttcttc ccgtgttaat gagagtatgt gtttttatgt ggggatatgt acaccccata
      241 tagatgtatt atgttatatt tataatatac ctcggcaaaa taaaaggatt gttatagaaa
      301 tagggaaggc tataaaaaag cttatattaa ggtctgtttt cttcttagaa aaataattct
      361 ttgttctaat tattatagat gtaatccccc aaacaataaa aagaatggag ctgcttgtaa
      421 ttatttgata tatcaaaatt gttttcctct atttttgtgt agatagatgt taatggcact
      481 gggtgcattt attcgtaatt tctttttcca tgctgggcca gcaggagcat ttgaacagaa
      541 acttgattaa tcatgaaaac acatcactta tcgaagaaaa aaatataaac taacagaata
      601 actatagatg cagggaaagc taagaataag cttatagctg gggctgtttt tttgttgaat
      661 ttccagtttg tgactctgat tattacagct atagtcatcc agactataat taaaatagaa
      721 ctgccattga taaaatcata tttcaaaata aattctcctg tatttgtcac tcaatcggtg
      781 gtttatgtga ctatattcgc aaaaactggt cgcagaaaag tcctgttttc agcttggaaa
      841 cccggtaatc agaataatgg ataggggaac aaaaatctct gtatagaacg ctccattgag
      901 ggagagaaaa cgtgtcattt tgacccgttc ggtattcaga acacacaaaa ccgatcgcgg
      961 gtcgctttcg tgcatagtta tgcagccatc taaaaacgat tctggcgcgt ttttctggtt
     1021 tagcctggtg ttttcttgtc tttttgcgtt ttttgcgcca gaaagcgatt gagggcgttt
     1081 tacagggtac gtacaacggg agttatggta aatggatcgg gttttcggga aggttcgaca
     1141 ggatttgccg ttgggtgtag tgtaagcgac tgaaaaacaa acgcccctga aatcatgtcc
     1201 agatccggca gaaccagcct catgcgcagt tctggctggt ttttgacgtt gatcgcgagg
     1261 gggcagcgat tgactggagc gaccggaacg ctcccgcgcc gaacatcacc gtaaaaaatc
     1321 ctgtgaacgg tcatgctcac ctgctctacg cgctcaatat cgccgtgaga accgcgccgg
     1381 acagctcggt taaggcgctg aaatacgccg ctgcgattga acgttcgctg tgtgagaaac
     1441 tttgtgctga tgtgaactac agcggactga tttgtaaaaa tccgttccac ctggaatggc
     1501 aggtgatgga gtggcgagag gaagcctata ccctcgatga actggctgat tatctcgatt
     1561 tgagcgcctc agcgcgccgt agcatcgata aacattacgg gatggggcga aactgccacc
     1621 tgttcgaaat gacgcgcaaa tgggcttaca gggcgattcg tcagggctgg cccgaattct
     1681 cacagtggct tgatgccgtg attcagcgtg tcgaaatgta caacgcatcg cttcccgttc
     1741 cgctttcacc gcctgaatgt cgggctattg gcaagagcat tgcgaaatac acgcacagga
     1801 acttcacgcc ggaaactttc gcacagtatg tggctgatac gcacacatta acgtacgttt
     1861 tcgttccatt ggccctcacc ccccgataac gacccaggta gcgcgccgta ttccccccgc
     1921 cggccgtttt cttcgacatg tacatcaggc gcggaactca tcgggacgcg ggaatgaaat
     1981 cccattcaga ctccggatag attcaagcaa gcccacttat cgtcaaaatc ggtgttgcaa
     2041 aaacgggagt gaccatagat ccgttttcca agcggaccca taatatcggc tggtaaacat
     2101 cactcgctag tgcattcttt ttgttggtaa tgataatcat ttacattcat tctttgatgt
     2161 tttatcataa ttaatgtttt gtcaataaat atatggaaac atattgtttc agatgggaat
     2221 atgagaaagt tcatccttat ttctatgata acgttagcta gtgttagtct gggagcctgc
     2281 agacagaatg tcaccataaa gcaggatgcg ccagggcaga aagctttcct gactgacggg
     2341 cagatttacg atttgcacag tggcaaaatt atttctagca gcgagctttt ggcggatctt
     2401 gctaccgctc aacatcttat tattggtgaa aaacacgata atgccgagca tcatcagatt
     2461 gagctttggc ttattcaaaa tttgctcatc cagcgaccac aggggagtgt gttgcttgag
     2521 atgttgacgt cagagcaaca gccccgagtt aaccaagtta aatgttggct gaaagataat
     2581 cctgtggttc gagatagccg tgttcaggaa ctacttaact ggcaaaaagg gtggtcctgg
     2641 gagatgtatg gcgacatcgt catgcagcta ttacgtgggc cttacccgct gctcaatgcc
     2701 aacattggcc gggagcagat attggcactg tacaaaaaaa acgaatttcc taaaggaaaa
     2761 aaatccactg cacctgtggt acaagaagct ctgcgtgaaa ccatcatatc tatgcatgaa
     2821 ggcaaccttg aaagccagca actgacgtca atgctctcta ttcagcagca gcgggatcgc
     2881 tacatggccc gccagcttct gagtgccccg gtaccgtcgt tgttgattgc aggtggttat
     2941 cacgcgtcaa aaagcatggg cgtaccgtta cacatggaag atcttgccac cggcacccat
     3001 ccagtggtgt tgatgcttgc agaaaaagga atgaacatca cagtagatca tgctgactac
     3061 gtgtggtttg tagcgccaga tacaacaaaa aggtaaacca tggatgatga atattctcca
     3121 cttctcacag tcggtaaaat ggagcagctg gtttatctgt tctctactgc ttcatggact
     3181 gattttcctt gcgtttatct ggcgtttttc cgaagttcag cccgctatgt ctcctgcacc
     3241 ggcgatcatg ctgcaatggg cagaaattat agaggctcct tcttctccac tttcgcttcc
     3301 ggtgggaatc gctcaacagg agtccgcagt gacagaagaa aagcaacaaa ctgaggacag
     3361 acaacaacgt cctgtcactg aagacagtga tgcaaccatt gaaataacta ggaagaaaaa
     3421 gtcatccgat ggagaaaaga aaaagacacg tccacctcgt aagataaagg ctcaaaccag
     3481 cgacagcaac cccacagccg tttccagtaa tgctgcacct caggctctgg tcgaatcgtc
     3541 ccgtattgct gcgcctttta acagtgactc aacaaagcga gataattctg aggcatcttg
     3601 ggaaagcaga gtaaaaggcc acctaaaccg ttataaacgt taccctggcg atgccagaaa
     3661 acgtgcacga accggcacag ccgtcgtgac ttttaccgta aacacggaag gcactattgt
     3721 cagtagtttc ttggaaatct cttcaggaac cttttctctt gaccgcgaag ctattgctgt
     3781 tttagaacgc gctcaaccac ttcccaaacc accgcctgaa atattggagg gaggattatt
     3841 taaagtaaaa atgccgatta cctttaagtt gaaggagtaa agggataatt ggccgttcaa
     3901 gttcatttaa ctgaaattta attttcattt ttatgctgaa cattttatca aacttttcca
     3961 ctgtcaaaaa aatcaaaaag acagtagaac ataattaata aacaaatagt tatacttatc
     4021 tttattaata ttatacccaa ggaaatttat gaacgttata aaactggcta tcggctcagg
     4081 catattattg ctcagctgcg gtgcttactc acaatccatc agtgaaaaaa ctaattccga
     4141 caaaaaagga gcggcagaat tcagtccgct cagcgtttct gtcgggaaga cgaccagtga
     4201 gcaggaagct ctcgagaaaa caggcgcgac cagttcccgg acaacggaca aaaacctgca
     4261 atcacttgac gcaacagtgc gtagtatgcc tggtacttat actcaaatag atcctggtca
     4321 gggagcaatc agtgtgaata ttcgaggcat gagcggattt ggtcgtgtaa acactatggt
     4381 cgatggtatt acccagagtt tttacggaac ctctacctcc ggaacaacga cgcatggttc
     4441 aactaacaat atggctggcg tacttataga tcctaactta ctggtagcag ttgatgttac
     4501 acgcggtgac agcagtggct ctgaagggat caacgccctt gccggtagtg caaatatgcg
     4561 tactattggc gttgacgatg taatatttaa cggtaataca tatggccttc gttcacgttt
     4621 ctctgtcggt agtaatgggc tgggacgcag cggaatgatc gcccttggtg gaaaaagcga
     4681 cgcttttacg gatacgggaa gcattggcgt tatggctgct gtgagcggca gttctgtgta
     4741 ctctaatttc tcaaatggtt ctggaattaa cagcaaagag tttggttatg ataaatatat
     4801 gaagcagaac cccaaatccc aactgtataa aatggatatc agaccagacg aatttaacag
     4861 cttcgaactt tccgctcgaa cctatgaaaa taaatttaca cgtcgtgata taaccagtga
     4921 cgactattac attaaatatc attacacccc tttttctgaa ttaattgact ttaacgtaac
     4981 ggccagtacc agtcgcggta atcaaaagta tcgtgatggc tcgctgtata ctttctacaa
     5041 aacctcagcg caaaatcgtt ctgacgcgct ggatatcaac aataccagcc ggttcactgt
     5101 cgcggacaat gacctggagt ttatgctggg cagcaaactg atgcgtaccc gctatgaccg
     5161 gaccattcac tcagcggcgg gcgacccgaa agcgaatcag gaatcgatcg agaacaatcc
     5221 gttcgcaccc tccggccagc aggatatttc agcgctgtat accgggctga aggttacgcg
     5281 cggcatctgg gaggcagatt tcaatctcaa ctacacacgt aacaggatca cagggtacaa
     5341 gcccgcctgc gattcacgcg ttatctgcgt gccacagggt agctacgata ttgacgataa
     5401 agagggtggc ttcaaccctt cagttcagct ttctgctcag gtaacaccat ggcttcagcc
     5461 gttcattggc tacagcaaat ccatgcgcgc cccgaacatc caggagatgt tcttctctaa
     5521 ttcaggaggc gcatccatga acccattcct gaagcctgaa cgtgcagaaa cctggcaggc
     5581 gggttttaac attgatacca gagatttact ggtcgaacag gatgccctgc gctttaaggc
     5641 tctggcgtac cgcagcagga tccagaacta catctacagc gagtcttatc tggtttgttc
     5701 tggaggtcgt aaatgcagtc tgcctgaggt gattggcaat ggctgggagg gcattagcga
     5761 tgaatacagc gacaatatgt acatctacgt taactcggca agcgacgtta tcgcaaaggg
     5821 cttcgaactg gagatggatt atgatgcagg ttttgctttt ggccgactct ctttcagcca
     5881 gcagcaaaca gaccagccaa cctccatcgc cagcacccac tttggcgcag gggatataac
     5941 cgaactgccc agaaaataca tgacgctgga tactggtgtt cgcttcttcg ataacgcgtt
     6001 gaccctgggc actatcataa aatacacagg caaggctcgt cgcctgtcgc ctgattttga
     6061 gcaggacgaa cataccggcg caataatcaa acaggatttg ccgcagatcc caacgattat
     6121 cgatctctat ggtacttacg agtacaaccg caacctgaca ctgaaacttt cggtacaaaa
     6181 cctgatgaac agagattatt cggaggcgct gaataagctc aacatgatgc caggtcttgg
     6241 tgacgagacc cacccagcca attccgcgcg tggcagaaca tggatatttg gcggggacat
     6301 tcgtttctga tgacaatttc cgctaggttc agacaatacg ttttctctct tatgtcaatt
     6361 ttattgcagg aacgaaaaat gaatattttc actttatcca aagcaccgct atacctgtta
     6421 atttcactat ttttacccac gatggccatg gctatcgatc cacctgaacg cgaactttcg
     6481 cgatttgccc tgaaaacgaa ttaccttcag tcccctgatg aaggcgtcta tgaactggcg
     6541 tttgataatg ccagtaaaaa ggtgtttgca gcagtcaccg atcgtgtaaa tcgtgaagcc
     6601 aataaaggct atctgtattc gtttaattca gattcgctga aagtcgaaaa taaatacacg
     6661 atgccatacc gggcattttc gctggcgata aatcaggata aacatcagct ctatatcgga
     6721 cacacccagt cagcgtccct gcgtatcagt atgtttgaca ccccaaccgg caaactggta
     6781 agaaccagcg acaggttaag ttttaaagcg gcaaacgctg cagattcgcg ttttgagcat
     6841 tttcgccata tggtttacag ccaggattcc gataccctgt ttgtgagtta tagcaatatg
     6901 ctgaaaacgg ccgagggcat gaagcctctg cataagctgt taatgctcga cgggacgacg
     6961 cttgccttaa aaggcgaggt taaggatgct tacaaaggta cagcgtatgg tctgacgatg
     7021 gatgaaaaaa cacagaaaat ctacgttggc ggaagagatt acatcaacga aattgatgcg
     7081 aaaaatcaga cgctgctgcg taccatcccg ttgaaagatc cgagaccaca aatcacaagt
     7141 gtgcagaatc tggcggtgga ctccgcttct gaccgtgcct ttgtggtggt attcgaccat
     7201 gacgatcgtt ccggtacaaa agatggactc tatatttttg acttacgcga cggtaaacag
     7261 cttggctatg tgcacacagg agccggagct aacgcggtga aatacaatcc gaaatataac
     7321 gaactgtatg tcaccaactt cactagcggc accatcagcg tagtggatgc caccaaatac
     7381 agcatcaccc gtgaatttaa catgccggtc tacccaaacc agatggtgtt gtcggacgat
     7441 atggataccc tttacattgg catcaaagaa ggctttaacc gcgattggga tcctgatgtg
     7501 tttgtggaag gagctaaaga acgtattctg agcattgatt tgaaaaagtc gtgatcgggg
     7561 ggaaaaaaca tgggataaaa actccgttat tccactaaac tggtcggact aggaaaagca
     7621 aacatctctg tcctgccggt acgcctgtta cgccgctcca tgaggctgag gaatctccag
     7681 aaaacgagac aggcacagca ttgtacgatc aactgatttg tgccaataat taaatgaaat
     7741 cacagctatg cctgttcatg gggttctagg ccggaacccc agatttttcc gattgtttgt
     7801 tttctaactg attattcagt agttttagag ggctgacgct cagtggaacg aaaactcacg
     7861 ttaagaggtt ttgactatga taaaagtcaa agtaggggtg agtttggata tggaaattat
     7921 tgtactataa ggagagcatg aaaaaccctg gggcagtcac tgaatgaggg accagcagcg
     7981 gtaaaataac cagcataatt tctgcatggt cgatttttat accgtgacag gctgtttttt
     8041 atacttgcac cgattcccgg gcacacttag cctgtgtcag gccggcatat acctcagcag
     8101 actgatatcc cgcgcgtttt tcttcagccc tgatacattc agccccgcaa tggcccggcg
     8161 gtataccatc cggccgccgc acagcacgca ttcgaacggg tcacgactca ggaactgttt
     8221 caccatttgt gcatagcaca ctttcgccac tgcttccggt ttatccatcc ccagagcacg
     8281 gtacacctgc ggcagcttct ctccacacac ccggttggca aggaacccga agtacctcac
     8341 catcttaaaa aactgaaccg ccccgggaat cctggagact aaacttcctg agaaagaggt
     8401 aaacaggatg actaaaaata ctcgtttttc ccccgaagtc cgtcaacggg cagtccgtat
     8461 ggttctggaa agtcagggcg aatatgactc acaatgggcg acaatttgtt ccattgcccc
     8521 aaagattggc tgtacaccgg agactctgcg tgtctgggta cgccagcatg agcgg
//
LOCUS       DAFGPF010000173         8478 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFGPF010000173 DAFGPF010000000
VERSION     DAFGPF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8478
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.173"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            312..1295
                     /locus_tag="LSX49_004767"
     CDS             312..1295
                     /locus_tag="LSX49_004767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HBL7171047.1"
                     /translation="MSERHLPDDQSSTIDPYLITSVRQTLAEQSAALQNLSKQLDSGQ
                     YQRVLNLIMNCKGHVILSGMGKSGHVGRKMSATLASTGTPSFFIHPAEAFHGDLGMIT
                     PYDLLILISASGETDEILKLVPSLKNFGNRIIAITNNGNSTLAKNADAVLELHMANET
                     CPNNLAPTTSTTLTMAIGDALAIAMIHQRKFMPNDFARYHPGGSLGRRLLTRVADVMQ
                     HDVPAVQLDASFKTVIQRITSGCQGMVMVEDAEGGLAGIITDGDLRRFMEKEGSLTSA
                     TAAQMMTREPLTLPEDTMIIEAEEKMQKHRVSTLLVTNKANKVTGLVRIFD"
     gene            1367..2515
                     /locus_tag="LSX49_004768"
     CDS             1367..2515
                     /locus_tag="LSX49_004768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide export inner-membrane
                     protein KpsE"
                     /protein_id="HBL7171048.1"
                     /translation="MLIKVKSAVSWMRARLSAISLADIQKHLAKIIILAPMAVLLIYL
                     AIFSQPRYMSESKVAIKRSDDLNSGSLNFGLLLGASNPSSAEDALYLKEYINSPDMLA
                     ALDKQLNFREAFSHSGLDFLNHLSKDETAEGFLKYYKDRINVSYDDKTGLLNIQTQGF
                     SPEFALKFNQTVLKESERFINEMSHRIARDQLAFAETEMEKARQRLDASKAELLSYQD
                     NNNVLDPQAQAQAASTLVNTLMGQKIQMEADLRNLLTYLREDAPQVVSARNAIQSLQA
                     QIDEEKSKITAPQGDKLNRMAVDFEEIKSKVEFNTELYKLTLTSIEKTRVEAARKLKV
                     LSVISSPQLPQESSFPNIPYLIACWLLVCCLLFGTLKLLLAVIEDHRD"
     gene            2539..4215
                     /locus_tag="LSX49_004769"
     CDS             2539..4215
                     /locus_tag="LSX49_004769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="HBL7171049.1"
                     /translation="MKLFKSILLIAACHAAQASAVIDINADPNLTGAAPLTGILNGQK
                     SDTQNMSGFDNTPPPAPPVVMSRMFGAQLFNGTSADSGATVGFNPDYILNPGDSIQVR
                     LWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQSNVNVYAS
                     LLQAQPVKVYVTGFVRNPGLYGGVTSDSLLNYLIKAGGVDPERGSYVDIVVKRGNRVR
                     SNVNLYDFLLNGKLGLSQFADGDTIIVGPRQHTFSVQGDVFNSYDFEFRESSIPVTEA
                     LSWARPKPGATHITIMRKQGLQKRSEYYPISSAPGRMLQNGDTLIVSTDRYAGTIQVR
                     VEGAHSGEHAMVLPYGSTMRAVLEKVRPNSMSQMNAVQLYRPSVAQRQKEMLNLSLQK
                     LEEASLSAQSSTKEEASLRMQEAQLISRFVAKARTVVPKGEVILNESNIDSVLLEDGD
                     VINIPEKTSLVMVHGEVLFPNAVSWQKGMTTEDYIEKCGGLTQKSGNARIIVIRQNGA
                     AVNAEDVDSLKPGDEIMVLPKYESKNIEVTRGISTILYQLAVGAKVILSL"
     gene            4225..4965
                     /gene="kdsB"
                     /locus_tag="LSX49_004770"
     CDS             4225..4965
                     /gene="kdsB"
                     /locus_tag="LSX49_004770"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001578967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HBL7171050.1"
                     /translation="MSKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQVAGV
                     AEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRLVEVMHKVEADIYINLQGDEPM
                     IRPRDVETLLQGMRDDPALPVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIP
                     YPRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESLEQLRLMNAGINIRTFEV
                     AATGPGVDTPACLEKVRALMAQELAENA"
     gene            4962..6989
                     /locus_tag="LSX49_004771"
     CDS             4962..6989
                     /locus_tag="LSX49_004771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HBL7171051.1"
                     /translation="MIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVDAIAVWGH
                     RPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGEPPLSLVVDDCCIYYDASKPSAL
                     EKLVQDKAGNTALISQAREAMHTIVTGDLSKYNLAPAFVADESERSDIVLVVDQTFND
                     MSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFAALRATQRVRLI
                     AENVSPQSLLRHVSRVYVVTSQYGFEALLAGKPVTCFGQPWYAGWGLTDDRHPQSALL
                     SARRGSATLEELFAAAYLRYCRYIDPLTGAASDLFTVLQWLQLQRNHQQQRNGYLWAP
                     GLTLWKSAILKPFLCTATNRLSYSRRCTAATACVVWGVKGEQQWLAEAQQKSLPLWRM
                     EDGFLRSSGLGSDLLPPLSLVLDKRGIYYDATRLSDLEVLLNHSQLTLAQQMRAEKLR
                     QRLVESKLSKYNLGADFSLPAEAKDKKIILVPGQVEDDASIKTGTVSIKSNLELLRTV
                     RERNPHAYIIYKPHPDVLVGNRKGNIPTELIAELADYQALDADIIQCIQRADEVHTMT
                     SLSGFEALLHGKQVHCYGLPFYAGWGLTVDEHHCPRRERRLTIADLIYQALIVYPTYI
                     HPTRLQPITVEEAAEYLIQTPRKPMFITRKKAGRVIRYYRKLIMFCKVRFG"
     gene            7024..8262
                     /locus_tag="LSX49_004772"
     CDS             7024..8262
                     /locus_tag="LSX49_004772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBL7171052.1"
                     /translation="MQGNALTILLSGKKYLLLQGPMGPFFNDVAEWLESLGRNAVNVV
                     FNGGDRFYCRHRQYLAYYQTPKEFPGWLRALHRQYDFDTILCFGDCRPLHKEAKRWAK
                     SKGIRFLAFEEGYLRPQFITVEEGGVNAYSSLPRDPDFYRKLPDMPAPHVENLKPSTM
                     KRIGHAMWYYLMGWHYRHEFPRYRHHKSFSPWYEARCWVRAYWRKQLYKVTQRKVLPR
                     LMNELDQRYYLAVLQVYNDSQIRNHSNYNDVRDYINEVMYSFSRKAPKESYLVIKHHP
                     MDRGHRLYRPLIKRLSKEYGLDERVIYVHDLPMPELLRHAKAVVTINSTAGISALIHN
                     KPLKVMGNALYDIKGLTYQGHLHQFWQADFKPDMKLFKKFRGYLLVKTQVNGGYYGGV
                     KFENALGMNKDFLFGSKSIS"
BASE COUNT         2207 a         2013 c         2158 g         2100 t
ORIGIN      
        1 ttaatagtca agtaggaaac attttaacaa atgataaaaa tcctaaattc cttgttcata
       61 atgtaggagt gtgttaaata ggtgggcaaa atttggttcc ctttctcgcc tgtaatattg
      121 cagcgtcttc gcacctccat gagacattgc gacttaataa gaaggtgata agtcctgcat
      181 ataagcatgg actgaccatg gttttatatt cattaaaaat tttgttacaa cccattgatt
      241 tagcataaat aaattatagt gggttcgggt ttgttgtgac tgtggcatta tttccgtgca
      301 aaggagctga tatgtctgaa agacatttac ctgatgacca gagcagtact atcgatccat
      361 atctaattac ctctgttcgc cagactctgg cagaacaaag cgcagcatta caaaacttgt
      421 ctaaacaact ggattccggg cagtaccagc gtgtccttaa tttgataatg aactgtaaag
      481 ggcacgttat tctttcggga atgggtaaat cagggcatgt cggtcgtaaa atgtcagcga
      541 cgctggcctc tacgggtacg cctagtttct ttattcatcc tgcagaagct ttccatggcg
      601 atctgggcat gattacgcct tacgatcttc tgatccttat ttctgccagc ggtgaaacgg
      661 atgaaatcct caagctagtt ccttcactga aaaatttcgg caaccgaatt atcgccatta
      721 ccaataatgg aaattccacg ctggcgaaaa atgctgatgc cgtgctggaa ctccacatgg
      781 cgaatgaaac ctgcccgaat aatcttgcac caacaacgtc taccacgctg acgatggcga
      841 tcggcgatgc gctggcgatt gccatgatcc accaacgcaa atttatgccg aatgattttg
      901 cgcgctatca cccgggcggt tcattaggtc gtcgcctgct gacccgcgtt gctgatgtca
      961 tgcagcatga tgttcctgcg gtacagctgg atgcgtcatt taaaaccgtg attcaacgta
     1021 tcaccagcgg atgccaggga atggtgatgg tagaagacgc agaaggtggg ctagcgggca
     1081 ttatcaccga cggtgacctg cgtcgcttta tggaaaaaga gggttctctg acatccgcta
     1141 cggctgcgca gatgatgaca cgtgaaccgc tgacgctacc ggaagacacc atgatcattg
     1201 aagcggaaga aaaaatgcaa aagcaccgcg tctcaacgtt attggtgacc aacaaggcaa
     1261 ataaagtcac tggccttgtg cgcattttcg actaattaag caacggggtt cgagaggtta
     1321 gtctctcatt gagtttgcgc cccactgaaa ctttgataat cgttacatgt tgataaaagt
     1381 gaagtctgcc gtatcctgga tgcgtgctcg tctgtctgcc atctcactgg cagatatcca
     1441 aaagcacctg gcaaaaatca tcattctggc accgatggcg gtgctgctga tctatctggc
     1501 tatcttcagc cagcctcgct atatgagcga gtcgaaagtc gccattaaac gctcggatga
     1561 tttaaacagc ggcagcctga attttggtct gcttctgggt gcctctaacc ccagttccgc
     1621 agaagatgcg ttgtatctga aagagtacat caactcgccg gatatgctgg cggcgctgga
     1681 taagcaacta aattttcgtg aagcgtttag ccacagcggg ctcgattttc ttaatcatct
     1741 tagcaaggat gaaaccgcag aaggcttcct gaagtactac aaggaccgta tcaacgtctc
     1801 gtatgacgat aaaaccggat tactgaatat tcagacgcag ggctttagcc cggagtttgc
     1861 gcttaagttt aaccaaaccg tgctgaaaga gtcagagcgc tttatcaatg agatgtcaca
     1921 tcgcatcgcg cgtgaccagc ttgcctttgc agaaacggag atggaaaagg cacgccagcg
     1981 tctggacgcc agcaaagcgg aattgctctc ttatcaggac aacaacaacg ttctggatcc
     2041 acaggcacag gcacaggcgg cgagcacgtt agtgaatacg ctgatgggcc agaagatcca
     2101 gatggaagcg gacctgcgga acttgctgac gtatctgcgt gaggacgccc cgcaagttgt
     2161 gagtgcgcgt aatgcgattc agtcattgca ggcacaaatt gacgaagaaa aaagcaaaat
     2221 cactgcgcca cagggtgaca agctaaaccg tatggcagtg gattttgaag aaatcaaatc
     2281 aaaagtagag ttcaacaccg agctgtacaa actgaccctg acctccattg aaaagacccg
     2341 tgtagaagcg gctcgtaagc tcaaggtgct gtcagtgatc agttcgccac agttgccgca
     2401 ggaatcgtct tttccaaata tcccttattt gatcgcctgc tggttactgg tgtgctgctt
     2461 actgttcggc accctgaaac tgttgctggc tgttattgaa gatcaccgag actaacgctg
     2521 tcgctgaatg agtttgtgat gaaattattt aaatcaattt tactgattgc cgcctgtcac
     2581 gcggcgcagg ccagcgcggt cattgatatt aacgctgacc caaacctgac aggagccgcg
     2641 ccgcttaccg gtattctgaa cggacagaag tcggatacgc aaaacatgag cggcttcgac
     2701 aataccccgc cgcccgcacc gccggtggta atgagccgta tgtttggtgc tcaacttttc
     2761 aacggcacca gcgcggatag cggtgcgacg gtaggattca accctgacta tattctgaat
     2821 ccgggtgata gcattcaggt tcgcttgtgg ggtgcgttca cctttgatgg tgcgttacag
     2881 gttgatccca aaggtaatat tttcctgccg aacgttggtc cggtgaaagt tgctggcgtc
     2941 agtaatagtc agctaaatgc cctggtcaca tccaaagtga aggaagtata ccagtccaac
     3001 gtcaacgtct acgcctcctt attacaggcg cagccagtaa aagtgtacgt gaccggattt
     3061 gtgcgtaatc ctggtctgta tggcggtgtg acgtctgatt cgttactcaa ttatctgatc
     3121 aaggctggcg gcgttgatcc agagcgcgga agttacgttg atattgtggt caagcgcggt
     3181 aaccgcgtgc gctccaacgt taacctgtac gacttcctgc tgaacggcaa actggggctt
     3241 tcgcagttcg ccgatggtga caccatcatc gtcgggccgc gtcagcatac tttcagcgtt
     3301 cagggcgatg tctttaacag ctacgacttt gagttccgcg aaagcagcat tcccgtaacg
     3361 gaagcgttga gctgggcgcg ccctaagcct ggcgcgactc acattacgat tatgcgtaaa
     3421 caggggctgc aaaaacgcag cgaatactat ccgatcagtt ctgcgccagg ccgtatgttg
     3481 cagaacggcg ataccttaat cgtgagcact gaccgctatg ctggcaccat tcaggtgcgg
     3541 gttgaaggcg cacactccgg tgaacatgcc atggtactgc cttatggttc cactatgcgt
     3601 gcagttctgg aaaaagtccg cccgaacagc atgtcgcaga tgaacgcagt tcagctttat
     3661 cgcccatcag tggctcagcg tcagaaagag atgctgaatc tctcgctgca aaagctggag
     3721 gaagcatcac tttctgccca gtcatccacc aaagaagaag ccagcctgcg aatgcaggaa
     3781 gcacaactga tcagccgctt tgtggcgaaa gcacgcaccg tggttccgaa aggtgaagtg
     3841 atcctcaacg aatccaatat tgattctgtt ctgcttgaag atggcgacgt catcaatatt
     3901 ccggagaaaa catcgctggt tatggttcat ggcgaagtgc tgttcccgaa cgcggtgagc
     3961 tggcagaagg gtatgaccac cgaggattac atcgagaaat gtggtggcct gacgcaaaaa
     4021 tcgggtaacg ccagaattat cgtcattcgt cagaacggtg cagccgtcaa cgcagaagat
     4081 gtggattcac tcaaaccggg cgatgagatt atggttctgc cgaaatatga atcgaaaaac
     4141 attgaagtta cccgtggtat ttccaccatc ctctatcagc tggcggtggg tgcaaaagtg
     4201 attctgtctt tgtaaggggt tgaaatgagc aaagcagtta ttgtcattcc ggctcgctat
     4261 ggctcctcgc gcctgccggg taagccactg ctcgatattg ttggtaaacc gatgatccag
     4321 catgtttacg agcgtgcgtt acaggtggcg ggcgttgcgg aagtttgggt ggcaacagac
     4381 gatccgcgtg ttgaacaggc cgtacaggcg tttggcggga aagccatcat gacgcgcaac
     4441 gatcatgaat ccggcaccga tcggctggtc gaggtgatgc ataaagtcga ggcagatatc
     4501 tacattaacc tgcagggcga cgaaccaatg attcgcccgc gggatgtaga aacgctgcta
     4561 caaggaatgc gtgacgatcc cgcgttgccg gtggcaacgc tatgccacgc gatttctgcc
     4621 gcagaagcgg ctgagccaag cacggtaaaa gtggttgtga atacccgcca ggatgcgctt
     4681 tatttcagcc gctcaccgat tccgtatccg cgtaatgctg aaaaagcgcg ctacctgaaa
     4741 cacgtcggta tttacgctta tcgtcgcgat gtgctgcaaa actacagcca gttaccggag
     4801 tccatgccgg agcaggcgga atcactggag cagctaaggt tgatgaacgc ggggatcaac
     4861 atccgcacat ttgaggttgc cgcaaccggt ccgggcgtcg acaccccagc atgcctggaa
     4921 aaagtgcgcg ccctgatggc acaggaactg gctgaaaacg catgattggc atttactcgc
     4981 ctggcatctg gcgtattccg catctggaga aatttctggc gcaaccgtgc cagaaacttt
     5041 ctctgctgcg ccctgttcca caagaagttg atgctatcgc cgtgtgggga catcgtccca
     5101 gcgcggcgaa accagtcgcc atcgccaaag cagcgggaaa acccgtcatt cgtctggaag
     5161 atggatttgt gcgttcgctg gatcttggcg tcaatggcga gccgccgctt tctctggtgg
     5221 tggatgattg ttgcatttac tacgatgcca gcaagccttc agcactggag aaactggtac
     5281 aggataaagc cggaaataca gctctgataa gccaggccag agaagcgatg cacaccatcg
     5341 tgaccgggga tttgtcgaaa tataacctgg cacctgcgtt tgtggctgat gagtcagaac
     5401 gttcagacat cgttctggtt gtcgatcaga catttaatga tatgtcagtg acgtatggca
     5461 atgctggccc gcatgagttt gctgccatgc tggaagccgc gatggcggaa aatcctcaag
     5521 ccgaaatttg ggtgaaggtg catccggatg tcctggaagg aaagaaaaca ggttatttcg
     5581 ccgctctgcg cgccacgcaa cgagtacgtt taattgccga gaatgtcagc ccgcagtcgc
     5641 tgttgcgaca cgtttcccgg gtttacgtcg tgacctccca gtacggcttt gaagccttgc
     5701 tggcaggaaa accagtaaca tgtttcggcc agccctggta tgcaggctgg ggcttaaccg
     5761 acgatcgcca tccgcagtcc gctttgttat ctgcccgacg cggttctgcc acgctggaag
     5821 aactttttgc cgctgcatac ctgcgttact gtcgctatat cgacccgctc acgggggccg
     5881 caagcgatct gtttaccgta ctgcaatggc tgcaattaca gcgcaaccat cagcaacagc
     5941 gtaatggcta tttatgggcg ccaggcttaa cgctgtggaa gtcggcaatc ctgaaacctt
     6001 tcttgtgtac cgcaacaaac agactgagtt attcacgccg ttgtactgcg gcgacggctt
     6061 gcgtggtatg gggtgtaaag ggagaacagc aatggctagc cgaagcgcaa caaaaatcac
     6121 tgccgttatg gcgaatggaa gatggttttc tgcgttcatc cggacttggc tctgaccttt
     6181 tgccgccgct atcgttggta ctggataaac gcgggatcta ctatgacgcc acgcgcctca
     6241 gcgacctgga agtcctgctt aatcacagcc agttaacgct ggcgcagcag atgcgagctg
     6301 aaaaattacg ccagcgactg gttgaaagca aactgagcaa atacaacctg ggggccgatt
     6361 tctctctgcc tgccgaggcc aaagataaaa aaatcatcct ggtgccgggt caggtagaag
     6421 acgatgcctc aattaaaaca ggcactgtgt cgattaagag caaccttgag ttattacgca
     6481 cagtacgcga gcgcaatccg cacgcttaca ttatttataa accgcacccg gatgtactgg
     6541 tggggaatcg caagggcaat attccgacag aactaattgc tgaactcgct gattatcagg
     6601 cactggacgc agatattatt caatgcatcc agcgcgcaga tgaagtgcac accatgacat
     6661 cattgtccgg gtttgaagcg ttattacatg gcaagcaagt tcattgttac ggcctgccct
     6721 tctatgccgg ttggggttta accgttgatg aacatcattg cccgcgccgc gagcgcagat
     6781 taacgatagc agacttgatc tatcaggcgt tgattgttta cccaacatat attcacccaa
     6841 cacggctaca gcctattacg gttgaggaag ctgcggaata tttaatccag acgccgcgta
     6901 agccgatgtt tattacccga aaaaaagcgg ggcgggtaat acgctattac cgcaaattaa
     6961 ttatgttctg caaggtcaga tttggctaaa caatttcata gttgactatt acacagatta
     7021 tttatgcaag gcaacgcact aaccatttta ttatcgggta aaaaatatct gctattgcag
     7081 ggaccgatgg gacctttttt caatgacgtc gccgaatggt tagagtcatt aggccgtaac
     7141 gctgtgaatg ttgtcttcaa cggcggggat cgtttttact gccgccatcg acaatacctg
     7201 gcttactacc aaacgccgaa agagtttccc ggatggttac gggctctcca ccggcaatat
     7261 gactttgata ccatcctctg ctttggtgac tgccgcccat tgcacaaaga agcaaaacgc
     7321 tgggcaaagt cgaaagggat ccgctttctg gcatttgagg aaggatattt acgcccgcaa
     7381 tttataaccg ttgaagaagg cggagtgaac gcatattcct cgctaccgcg cgatccggat
     7441 ttttatcgta agttgccaga tatgcctgcg ccgcacgttg agaacttaaa accttcaacg
     7501 atgaaacgca ttggccatgc gatgtggtat tacctgatgg gctggcatta ccgtcatgag
     7561 ttccctcgct accgccacca caaatcattt tccccctggt atgaagcacg ttgctgggtt
     7621 cgtgcgtact ggcgcaagca actttacaag gtaacacagc gcaaggtatt gccgaggtta
     7681 atgaatgagc tggatcagcg ttattatctt gccgttttgc aggtgtataa cgatagccag
     7741 attcgtaacc acagtaatta taacgatgtg cgtgactata ttaatgaagt catgtactca
     7801 ttttcacgta aagcgccgaa agaaagttat ttggtgatca aacatcatcc gatggatcgt
     7861 ggtcacagac tctatcgacc attaattaag cgattgagta aggaatatgg cttagatgag
     7921 cgagtcattt atgtgcacga tctcccgatg ccggaattat tacgccatgc aaaagcggta
     7981 gtgacgatta acagtacggc ggggatctct gcgctgattc ataacaaacc actcaaagtg
     8041 atgggcaatg ccctgtacga catcaaaggc ttgacgtatc aagggcattt gcaccagttc
     8101 tggcaggccg attttaaacc ggacatgaaa ctgtttaaga agtttcgggg gtatttattg
     8161 gtgaagacgc aggttaatgg gggttattat ggaggagtaa aatttgagaa tgcattgggt
     8221 atgaataaag attttttgtt tggatcaaag tcaatatcat aatttattct aaattatcaa
     8281 cgtagaataa aagcattacc ttcaagaatc cttattttta taactatatg actcataaaa
     8341 atatattcct atatatttag ttcatataat tattttacca tataaacata tcacttttat
     8401 ataatgaaaa ctcgtctgat ttcttattga gtaaattcat ccagtagaat aatgatccct
     8461 tcacttctgg aggtttta
//
LOCUS       DAFGPF010000174         8146 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFGPF010000174 DAFGPF010000000
VERSION     DAFGPF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8146
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.174"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            45..1211
                     /locus_tag="LSX49_004773"
     CDS             45..1211
                     /locus_tag="LSX49_004773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBL7171053.1"
                     /translation="MIEHYIRGFEEELREIRHQIHENPELGLQEFKTSALVAEKLRQW
                     GYEVEQGLATTGVVATLKVGDGEKSIGLRADMDALPIYENSGKPWASKHPGLMHACGH
                     DGHTTILLGAARYFAETRRFNGTLRLIFQPAEEMINGGEIMVKEGLFDRFPCDVIFGM
                     HNMPGLPVGKFFFQPGALMASMDQFHITVRGCGGHGAIPHKAIDPVLVAAHITTALQS
                     IVSRNVDPLEAAVITVGSIVAGEAANVIPDSAEMKISVRSLSRDTRQLLLTRIPALAQ
                     TQAASFGATAEVTHVNGTPVLVNDEEMARFAWQVACKTFGEDRAEFGIKPLMGSEDFS
                     FMLEAQPKGGFLLFGNGDVGEGSCMVHNPGYDFNDASLVPASSYWGALVEAWLQ"
     gene            1254..2570
                     /locus_tag="LSX49_004774"
     CDS             1254..2570
                     /locus_tag="LSX49_004774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7171054.1"
                     /translation="MTAIVNETVSVKKKPSGRRVIFASAFGNALEFFDFGVYNFFVVY
                     ISTLFFPPSADHNVALLLAFATFGVSFFMRPLGGIIVGAWADRFGRKPAMVFTIALMS
                     LGTLMIGIAPTYETAGYWGTATLVLARLIQGVAAGGEVGASMSLLVESAPANRRGFYS
                     SWSLATQGLATTFGGVVALGLSAWLPFATGSETVMAEWGWRVPFFIGVLLAPIGCWLR
                     LSLENDVPEPVRNKKAATSESAFSLLLQHKATIVNGVLLAIGSTVATYISLFYYGTWA
                     AKYLAMPQHYSHAAMLLAGVVTFVGALLVGMLCDSVGRKKLILISRVMVLLCSWPSFW
                     LLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLLISELLPKRIRALGFALVYSIGVAIFG
                     GFAQYFATQSIVLLDSLTAPAWYLGGGTLLSMLALLYVKEPAKELQ"
     gene            2674..3324
                     /gene="fabR"
                     /locus_tag="LSX49_004775"
     CDS             2674..3324
                     /gene="fabR"
                     /locus_tag="LSX49_004775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HBL7171055.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
     gene            3324..3683
                     /locus_tag="LSX49_004776"
     CDS             3324..3683
                     /locus_tag="LSX49_004776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HBL7171056.1"
                     /translation="MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLV
                     LTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIM
                     VFWIGAKMRNRKQDVAE"
     gene            complement(3723..4823)
                     /gene="trmA"
                     /locus_tag="LSX49_004777"
     CDS             complement(3723..4823)
                     /gene="trmA"
                     /locus_tag="LSX49_004777"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HBL7171057.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPILR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWCQQAEALRDALRAQNLNVHLIGRATKTK
                     IALDQDYIDERLPIAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     regulatory      4937..5127
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            5192..7036
                     /gene="btuB"
                     /locus_tag="LSX49_004778"
     CDS             5192..7036
                     /gene="btuB"
                     /locus_tag="LSX49_004778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HBL7171058.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDHPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQPDNDGFL
                     SKTLYGALEHNFTDVWSGFVRGYGYDNRTNYDAYYSPGSPLVDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNIIIGHGNIGAG
                     VDWQKQSTAPGTAYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGSRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     gene            6981..7838
                     /gene="murI"
                     /locus_tag="LSX49_004779"
     CDS             6981..7838
                     /gene="murI"
                     /locus_tag="LSX49_004779"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBL7171059.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEVFIVERVVEIVTAVQERYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFE
                     TLEKLAVLD"
BASE COUNT         1869 a         1922 c         2210 g         2145 t
ORIGIN      
        1 aatccgttaa ttagcctgtt tataagtgaa taaaggaata gccgatgatc gaacactata
       61 ttcgtgggtt tgaggaagaa cttcgcgaga tccgccatca gatccacgaa aacccggagc
      121 tgggattaca agaatttaaa accagtgctt tggttgcgga aaagctgcgc cagtggggct
      181 atgaggttga gcaagggctg gcgacaaccg gcgtggtagc cacgttaaaa gtgggcgacg
      241 gagagaaaag tattggcctg cgggcggata tggatgcgtt gccgatttat gaaaatagtg
      301 gcaagccctg ggccagtaaa catcctggtt taatgcacgc ctgcgggcat gacgggcata
      361 ccaccatact gctgggggcc gcgcgttatt ttgccgaaac ccgccgtttt aacggcacgt
      421 tacgccttat cttccagcca gcggaagaga tgattaacgg cggtgagatc atggttaaag
      481 aggggctttt tgatcgtttc ccctgcgatg tcattttcgg gatgcacaac atgccgggtt
      541 tgccggtcgg caagtttttc ttccagcctg gggcgctgat ggcgtcaatg gatcagttcc
      601 atattacggt tcgtggttgt ggcggacacg gtgcgatccc gcacaaagcc atcgatccag
      661 tgctggttgc cgcacatatc accaccgcat tacaaagcat tgtgtcgcgc aatgtcgatc
      721 cgctggaagc ggcggtaatt accgtcggca gcattgttgc gggtgaggcg gctaacgtca
      781 ttcctgacag tgctgagatg aaaatcagtg tccgctctct tagccgcgat acccgacaac
      841 ttcttctgac ccgtattcct gctcttgcac aaacccaggc tgccagcttt ggcgctacgg
      901 ctgaggttac gcatgttaac ggtacaccgg tattagtaaa tgacgaggag atggcgcgct
      961 tcgcctggca ggtggcgtgc aaaacatttg gtgaagatcg ggctgagttt ggcatcaaac
     1021 ccctgatggg cagtgaagat ttctctttca tgctggaggc ccaacccaaa ggcggtttcc
     1081 tgttattcgg taatggcgat gtcggggaag gttcctgcat ggtgcataac cccggttacg
     1141 actttaacga tgcaagcctg gtcccggcaa gcagctactg gggcgcactg gttgaagcct
     1201 ggctgcaata aataaaacaa cacacaacaa cactttttgg caaggaacat ggaatgacgg
     1261 cgatcgtaaa tgaaaccgtg agtgtgaaga aaaagcccag cggcaggcgg gtgatctttg
     1321 cctcggcgtt tggcaatgcg ctcgaatttt ttgattttgg cgtttacaac ttttttgtgg
     1381 tctatatcag tacgcttttc ttcccaccca gtgccgatca taacgtcgcg ctgttactgg
     1441 catttgcaac gtttggtgtg agctttttta tgcgtccgct cggtgggatt atcgttggtg
     1501 cctgggccga tcgcttcggg cgtaaaccgg cgatggtgtt cactattgct ctgatgagcc
     1561 tcggtacgct gatgatcggc atcgcaccga cgtatgaaac ggcgggctat tggggaaccg
     1621 caacgctggt gctggcgcgt ttgattcagg gcgttgcggc aggtggtgaa gtcggggctt
     1681 caatgtcgct actggtggag tcagctccgg caaatcgtcg tggcttttac agcagttggt
     1741 cactggcgac tcaaggcctg gcaacaactt ttggcggtgt tgtcgcttta ggtttaagcg
     1801 catggctacc gttcgccaca ggttcagaaa ccgtaatggc agaatggggc tggcgtgtgc
     1861 cgttttttat tggtgtgtta ttagcaccta tcggttgctg gttgcgtctg agcctggaaa
     1921 atgacgtacc tgagcctgtg cgcaataaaa aagctgctac cagcgaaagc gcgttttctc
     1981 tgctcctgca acataaggcg actatcgtta atggcgtttt actcgctatt ggtagcacgg
     2041 tcgcaaccta tatctccctc ttttattacg gcacctgggc ggcgaagtat ctggcgatgc
     2101 ctcaacatta ttctcatgca gcgatgttac tggcgggcgt tgttacgttt gtgggtgcgc
     2161 tgcttgtggg gatgttgtgc gattcggtcg ggcgtaaaaa gctgatttta atctcccgtg
     2221 tgatggtgct tctctgtagc tggccgtcat tctggctgtt ggtgaattac ccaagccctg
     2281 gcatgttgct gacggtggtt ttcgtgatgg tcagctttac cacgcttggc ggtgtgccag
     2341 tgatgttgtt gatctctgaa ctgttgccga aacggattcg ggcattgggt tttgcgctgg
     2401 tttatagcat tggtgtggca atctttggcg gttttgctca atatttcgct acgcaatcca
     2461 tcgtgttgct ggatagtctg acggctccgg cgtggtatct gggtggaggc acgttgctgt
     2521 cgatgctggc gttgttgtac gtaaaagaac cggccaaaga attgcagtaa atatgtttta
     2581 ttgcgttacc gttcattcac aacactggag caatccagta tgttcattct ctggtatagt
     2641 gccagcagta cttttggcaa ggattcagac atcgtgatgg gcgtaagagc gcaacaaaaa
     2701 gaaaaaaccc gccgttcgct ggtggaagcc gcatttagcc aattaagtgc tgaacgcagc
     2761 ttcgccagcc tgagtttgcg tgaagtggca cgagaagcag gcattgctcc cacctctttt
     2821 tatcggcatt tccgcgacgt agacgaactg ggtctgacca tggttgatga gagcggttta
     2881 atgctacgcc aactcatgcg tcaggcgcgt cagcgtatcg ccaaaggcgg gagtgtgatc
     2941 cgcacctcgg tctccacatt tatggagttc atcggtaata atcctaacgc cttccggtta
     3001 ttattgcggg aacgctccgg cacctccgct gcgtttcgtg ccgccgttgc gcgtgaaatt
     3061 cagcacttca ttgcggaact tgcggactat ctggaactcg aaaaccatat gccgcgtgcg
     3121 tttactgaag cgcaagccga agcaatggtg acgattgtct tcagtgcggg ggccgaggcg
     3181 ttggatgtcg gcgtcgagca acgtcggcaa ttagaagagc gactggtact gcagctgcga
     3241 atgatttcga aaggggctta ttactggtat cgccgtgaac aagagaaaac cgcaattatt
     3301 ccgggaaatg tgaaggacga gtaatgaaac aagcaaatca agatagaggt acgctgctgc
     3361 tggcgctagt ggctggctta tcgattaatg gtactttcgc agcgctgttt agctccattg
     3421 taccattttc tgtattcccg attatttccc tggtgttgac agtttactgc ctgcatcaac
     3481 gttatcttaa tcgcactatg ccggtaggct tgccgggtct ggcagctgct tgttttattc
     3541 tcggcgtact gctgtacagc acggtagttc gtgcggaata tccggatatc ggttccaact
     3601 tcttcccggc agtactgtcc gtcattatgg tgttctggat tggcgcgaag atgcgtaacc
     3661 gtaagcagga cgttgctgag taatcagcat catgccggat gcaggcgcat ccgacatggg
     3721 ttttacttcg cggtcagtaa tacgccgcac tccatatggt gcgtgtaggg gaactgatca
     3781 aatagagcca gacgttcgac cttgtgcgtc tggcttaatg tttccagatt cttgcataac
     3841 gtttccggat tgcaggagat atacagaata cgtggatacg cctgcaccat tttctcggtt
     3901 tcactgtcca gaccgctgcg cggtgggtcg acaaaaatgg tttcgcactg ataactcttt
     3961 aagtcgattc cttgcaggcg gttaaactcg cgcacaccat tcatcgcctg agtaaattct
     4021 tctgccgcca tacgaataat ttgtacgtta tcaatatggt tagcggcaat gttgtattgc
     4081 gcggcggcga ctgacggctt ggcgatttcg gtggctaata cccgatcaaa attgcgtgcc
     4141 agcgctaatg aaaagttacc gttgccgcag tatagctcca gtaaatcgcc ttttgagcct
     4201 ttggttacgt ccagcgccca ttccagcatc tgaatattca tcgccgcgtt cggttgggta
     4261 aagctgtttt ctacctgacg gtagatcatc tctttccccg cgatcggcag acgttcgtcg
     4321 atgtaatcct gatccagcgc gattttggtt ttcgttgccc gaccaatcag atgcacattc
     4381 agattctgcg cgcgcagtgc atcgcgcagg gcttccgcct gctgacacca ctcatcatcc
     4441 agctttttat ggtacagcaa ggaaacaacc gcttgattgc ttagcgtagt gaggtaatca
     4501 atctggaaca acttgtggcg cagaatggga ttattacgca cacccgcaat catcgccgtc
     4561 atcaactggt tgataagttc actggcggcg gggaagctat ccacacggat acgacttttg
     4621 gtttgttgat cgaaaatgat gtggtacagg tcatcgccat cgtgccagat gcggaactcc
     4681 gcacgcatcc gataatgact gaccggcgag cgaaacactt ccggaaccag gtcagaaaac
     4741 ggtgccatca tactttgcaa acgtaccact ttttcggcta actgcgcttc atactgttct
     4801 gttggaaggt gttcgggggt catgatgtat cctgaaaaat taaagtacgc ggcgattgta
     4861 gggattgctc atcagatgtc cagatcttga tgaattccta tttgtgagct acgtctggac
     4921 agtaacttgt tacaacctgt agcatccact tgccggtcct gtgagttaat agggaatcca
     4981 gtgcgaatct ggagctgacg cgcagcggta aggaaaggtg cgatgattgc gttatgcgga
     5041 cactgccatc cggtgggaag tcatcatctc ttagtatctt agatacccct ccaagcccga
     5101 agacctgccg gccaacgtcg catctggttc tcatcatcgc gtaatattga tgaaacctgc
     5161 ggcatccttc ttctattgtg gatgctttac aatgattaaa aaagcttcgc tgctgacggc
     5221 gtgttccgtc acggcatttt ccgcttgggc acaggatacc agcccggata ctctcgtcgt
     5281 tactgctaac cgttttgaac aaccgcgcag cactgtgctt gcgccaacta ctgttgtgac
     5341 gcgtcaggat atcgaccgct ggcagtcgac ctcggtcaat gatgtgctgc gccgtcttcc
     5401 gggcgtggat atcacccaaa acggcggttc aggtcagctc tcatctattt ttattcgcgg
     5461 tacaaatgcc agtcatgtgt tggtgttaat tgatggcgtc cgcctgaatt tggcgggggt
     5521 gagtggttct gctgatctta gtcagttccc tattgcgctt gtccagcgtg ttgaatatat
     5581 ccgtgggccg cgctccgctg tttatggttc agatgcaata ggcggggtcg tgaatatcat
     5641 cacgacgcgc gatcaccccg gaacggaaat ttcagcaggg tggggaagca atagttatca
     5701 gaactatgat gtctctacac agcaacaact gggggataag acacgggtaa cgctgttggg
     5761 cgattatgcc catactcatg gttatgatgt tgtcgcctat ggtaataccg gaacgcaagc
     5821 gcagccagat aacgatggtt ttttaagtaa aacgctttat ggcgcgctgg agcataattt
     5881 tactgatgtc tggagcggct ttgtgcgcgg ctatggctat gataatcgta ccaattatga
     5941 cgcatattat tctcccggct cgccactggt cgatacccgt aaactctata gccaaagttg
     6001 ggatgccgga ctgcgctata acggtgaact gattaaatca caactgatta ccagctacag
     6061 ccatagcaaa gattacaact acgatccgca ttatggtcgt tatgattcat ccgcgacgct
     6121 cgatgagatg aaacagtaca ccgtccagtg ggcaaacaac atcatcattg gccacggtaa
     6181 tattggtgcg ggtgttgact ggcagaagca gagcacggca ccgggcacag cttatgttga
     6241 ggatggatat gatcaacgta ataccggcat ctatctgacc gggctgcaac aagttggcga
     6301 ttttaccttt gaaggcgcag cacgtagcga cgataactca cagtttggtc gtcatggcac
     6361 ctggcaaacc agcgccggtt gggaatttat cgaaggttat cgctttattg cttcctacgg
     6421 gacatcttat aaggcaccaa atcttggaca actgtatggt ttctacggaa atccgaatct
     6481 cgaccctgag aaaagcaaac agtgggaagg cgcgtttgaa ggcttaactg ctggggtgaa
     6541 ctggcgtatt tccggatatc gtaacgatgt cagtgacttg atcgattatg atgatcacac
     6601 cctgaaatat tacaacgaag ggaaagcgcg gattaagggt gtcgaggcga ccgccaattt
     6661 tgataccgga ccactgacgc atactgtgag ttatgattat gttgatgcgc gcaatgcgat
     6721 tactgacacg ccgttgttac gccgtgctaa acagcaggtg aaataccagc tcgactggca
     6781 gttgtatgac ttcgactggg ggattactta tcagtactta ggttctcgtt atgataagga
     6841 ttactcctct tatccgtatc aaacagtgaa aatgggcggg gtgagcttgt gggatcttgc
     6901 tgttgcatat ccggtcacct ctcacctgac agttcgtggt aaaatagcca acctgttcga
     6961 caaagattac gagacagtct atggctacca aactgcagga cgggaataca ccttgtctgg
     7021 cagctacacc ttctgaacca cgtcccaccg tgctggtgtt tgactccggc gtcggtgggt
     7081 tgtcggtcta tgacgagatc cggcatctct tgccggatct ccattacatt tatgctttcg
     7141 ataacgtcgc tttcccgtat ggcgaaaaaa gcgaagtgtt tattgttgag cgagtggtgg
     7201 aaattgtcac cgcagtgcaa gaacgttatc cccttgcgct ggctgtggtc gcttgcaaca
     7261 ccgccagtac cgtttcactt cctgcattac gcgaaaagtt cgacttcccg gttgttggtg
     7321 tcgtgccggc gattaaacct gctgcacgtc tgacggcaaa tggcattgtc ggattactgg
     7381 caacccgcgg aactgttaaa cgttcttata ctcatgagct gatcgcgcgt ttcgctaatg
     7441 aatgccagat agaaatgctg ggctcggcag agatggttga gttggctgaa gcgaagctgc
     7501 atggcgaaga tgtttctctg gatgcgctaa aacgtatcct acgcccgtgg ttaagaatga
     7561 aagagccgcc agatacagtt gtattgggtt gcacccattt ccctctacta caagaagaac
     7621 tattacaagt gctgccagag ggaacccggc tggtggattc tggcgcagcg attgctcgcc
     7681 gaacggcctg gttgttagag catgaagccc cggatgcaaa atctgccgat gcgaatattg
     7741 cattttgtat ggcaatgacg ccagaagctg aacaattatt gcccgtttta cagcgttacg
     7801 gcttcgaaac gctcgaaaaa ctggcagttt tagattgatt tggttgaatg ttgcgcggtc
     7861 agaaaattat tttaaatttc ctcttgtcag gccggaataa ctccctataa tgcgccacca
     7921 ctgacacgga acaacggcaa acacgccgcc gggtcagcgg ggttctcctg agaatctcaa
     7981 cagaggaaag caaaaaaatg cttgactctg tagcgggaaa gcgtattatg tataccccgc
     8041 gccgctgaga aaagcgaagc ggcactgctc tttaacaatt tatcagacaa tctgtgtggg
     8101 cactcgaaga tacggattct tgacgtcgca agacgaaaaa tgaata
//
LOCUS       DAFGPF010000175         8004 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFGPF010000175 DAFGPF010000000
VERSION     DAFGPF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8004
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.175"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(72..485)
                     /locus_tag="LSX49_004780"
     CDS             complement(72..485)
                     /locus_tag="LSX49_004780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7171060.1"
                     /translation="MNTKTKNMAFASRLQRILKDLGWSQSELARHIGVTAQSVQAWCN
                     GVTPRKDKLDKLAKVTGYPVHFFFMNEGEYLDESTLHPGNYNQELTPQEQALLQLFRG
                     LPESEKNKLINELKEKREHFDLLLKELLEAKNQTK"
     gene            584..814
                     /locus_tag="LSX49_004781"
     CDS             584..814
                     /locus_tag="LSX49_004781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7171061.1"
                     /translation="MDKQLQDKILSVMSQSELGRRLGKKPQTVSLWFKGRVPGEEVLR
                     TSEALEWRVTPHDLRPDLYPNPDDSLPKTEAA"
     gene            873..1349
                     /locus_tag="LSX49_004782"
     CDS             873..1349
                     /locus_tag="LSX49_004782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000431205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171062.1"
                     /translation="MENQEELQKEILTWAARAGQELVTIEICRAWFSQGRNDELRLHE
                     FEDADGNVDWRAINNNRQKIFRWLRGETTAARRKTQVLASVMKAVLPAERRARLESPG
                     DPVLLATLAAKEGVEAINAVHLHFAPELTIQEIDEAIAALVATRGAVIRTAQDHHA"
     gene            1389..1613
                     /locus_tag="LSX49_004783"
     CDS             1389..1613
                     /locus_tag="LSX49_004783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171063.1"
                     /translation="MLRHIDRITWRNGWHLNGRPAHVAEIRPIFDGRVAAARSVWEKY
                     EEEKAKLREQNLSGAAYEAGCRVLSEALGI"
     gene            1610..2365
                     /locus_tag="LSX49_004784"
     CDS             1610..2365
                     /locus_tag="LSX49_004784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001023813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL7171064.1"
                     /translation="MNILPLLDRPIAFQRSFIRLEMGVTAALFLSQLTYWTNRTTDDG
                     WVYKTQDEWEEETGLSRYEQEGARKKLRGLGVLLERKQGLPARLYYKIDNDVLCQLLT
                     SAYKDAEKPHTGEGKTTRPVRGKPTNILTENTTEIITDGESADADTQQPADQRINYQV
                     ILDTYHEILPEMPPVKILTDGRKKHLRTFWKKFNFNESRWRAYLEFIGGNCRWMLEDR
                     PNGRGGFWRRKNLDYLITERCYVSVKEERANDK"
     gene            2355..3770
                     /locus_tag="LSX49_004785"
     CDS             2355..3770
                     /locus_tag="LSX49_004785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7171065.1"
                     /translation="MINNAIALYSVDAEQAVLGCLMLNTDHDRTNAVFALLKPETFYI
                     NAHQVIYREIKGLFQADKPTDLITLTELMESKGLYERVGGFAYLAEMSKAAIPASMVN
                     YAKIVREKAILRYAVEKLNSCLEIMIQPADMTATDRITAVQQVIGQVAEHSRTGHKGG
                     LRPASEVVDDWIDDLERRFNDPAHAAGLTLGIESLDRLMAPKQALRGSLVVIGARPKM
                     GKTAAFNKIAVHFALNHRLPTLVFSLEMTDRSLIERMVAQEAKVNSEIFYLGPNDESE
                     LSLAIAKAGEIAESNMMIDSTAGVTLAHIVAECRKVKRMRGSVGLVAIDYLTLMKTES
                     AERRDIAYGDITTGLKNLAKELDCVVVLLTQLNRKLEERADKRPNPSDSKDTGQIEQD
                     CDVWIGLYRDAVYNENADPNLMEMLLRLNREGPSGTAYALMKNGSVIDISDEEVYRLT
                     NDRSEKNKRYSRSDNSRTNEF"
     gene            3809..4219
                     /locus_tag="LSX49_004786"
     CDS             3809..4219
                     /locus_tag="LSX49_004786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171066.1"
                     /translation="MTTTPGKLEYPSDKGHIDDGKNYLDVILWNMNVGPRARTRAVFV
                     PRPKAGNFSTPAKPARQASVAAAPAVKRKGKTHTGIAIRRNGERQVKLHETATTWCAS
                     PHETYDKITGQRIGAPGRCRLLLSSITPIAKKGA"
     gene            4221..4457
                     /locus_tag="LSX49_004787"
     CDS             4221..4457
                     /locus_tag="LSX49_004787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171067.1"
                     /translation="MAGQSDYLPPGLPHNRAKWPQEYQLKEHYDMRAAALIRQLFEKR
                     IPRGSVIEQIGMTPDTYREFFRERLNYWRGVMEQ"
     gene            4454..4765
                     /locus_tag="LSX49_004788"
     CDS             4454..4765
                     /locus_tag="LSX49_004788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL7171068.1"
                     /translation="MKYKRWVRAEVVIIKQCAGSMTVERIGQLIGRTGAAVRTKAREL
                     KICMYLRGNYHQSVKYLQEDIELARELHQSGINRQDIAEKLEMPIGAVNQFVYFERRI
                     S"
     gene            4762..4986
                     /locus_tag="LSX49_004789"
     CDS             4762..4986
                     /locus_tag="LSX49_004789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171069.1"
                     /translation="MKELFLAFVPRFINDQIALTDNGEQYEIACSMVDVNPGERYDAM
                     CDLKIFTWLGWAIPCGEPTNIRPFESREAV"
     gene            5668..6456
                     /locus_tag="LSX49_004790"
     CDS             5668..6456
                     /locus_tag="LSX49_004790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBL7171070.1"
                     /translation="MTVQISAESLSPLHHNQLPVITTELLASLYGTEVNGIQQNFKRN
                     IARFVVGKHFFKLEGNELRDFKNRLTDSQSVAKHTRSLILWTERGAARHAKMLETEQA
                     WEVFEKLEDCYFSQRPERRSTTTDDRTPLRDAVNILVGKKGMMYPDAYTMIHQRFAVS
                     HIEQLSQTQMLEAIEYIHCLLLDENHPTIPDFSFITTIKNGKVTGMRHVAKGEHLMTF
                     DAFKEIAERAGYLVIHSDNLRSMTLDKLMVMGKKSAISVANSAF"
     gene            complement(6631..7554)
                     /locus_tag="LSX49_004791"
     CDS             complement(6631..7554)
                     /locus_tag="LSX49_004791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1311 domain-containing protein"
                     /protein_id="HBL7171071.1"
                     /translation="MRLKYSVLLLAIALTGCDNKKDEIGCSSEITQSALMDLLKKSAY
                     EGLSEQVDKYPDVTNQTKRSTLDKIKLAISEISTTSSDTGSTMKTCEGTVTMTLSANE
                     YVQLSDAYRKNFNRNLDKQMESLFLENNANAFSKRITYTVQATDDQKNVFVKTSTDNP
                     ISVGAALLTSLSIITPIVEQQKIQQAKDAQQSQIEAEQQVQLRAQEQAKYEAEKQIER
                     QAQLQPQKADNLDQSRMAFANADSDLSTVWSKLTPAKKKDLLPSQRQWIKTKDAMCGK
                     VSMQGTDAEVKKMVDCQTQMTLSRIAFLRNQ"
BASE COUNT         2173 a         1761 c         2066 g         2004 t
ORIGIN      
        1 tgtgtaaagg tgtttttgtg ttaggggaaa gttgcatgcc agcagcggct ggcctggaaa
       61 tttgaactga actattttgt ctggtttttg gcttcaagta gttcttttag cagtagatcg
      121 aagtgctctc ttttttcttt tagctcattg attaatttat ttttttcgct ctcaggcagt
      181 cctctgaata gttgcagtag agcctgttct tgcggggtta gttcttgatt gtaattaccc
      241 gggtgtagtg tggattcatc caaatattcc ccttcattca tgaagaaaaa atgaacaggg
      301 tatccggtca cttttgctag cttgtctaat ttatcttttc ttggagttac cccattacac
      361 catgcctgaa ctgattgagc cgtaacccca atatggcgag ctaactcaga ttgagaccag
      421 cctaagtctt ttagaatccg ttgtagtcgg ctagcaaaag ccatgttttt cgtttttgtg
      481 ttcataccgt aaggatacaa ggtttaattg tagggagcat tgcaaatata atttgtaatt
      541 acagttattg tttgtaatga tgacgcggac acaaggagtc catatggata aacaactgca
      601 agacaaaatt ctttccgtaa tgagtcaatc cgagttaggg cggcgattag ggaaaaaacc
      661 acaaacggta agcctctggt tcaaaggacg ggttcccggt gaagaggttt tgcgcacatc
      721 tgaagctctt gaatggcgcg tgacccctca tgatcttaga ccggatcttt acccaaaccc
      781 agatgacagc ttgcctaaaa cggaagcagc ttaactgttg gtgagcccca aatctgatta
      841 agcgtaatca atttttagcg acaggagacg ctatggaaaa ccaagaggaa ttacaaaaag
      901 agattttgac ctgggcggca agggcagggc aggaactcgt cacgattgaa atctgccggg
      961 cctggttcag tcagggacgc aatgatgagt tgagactaca tgaatttgag gacgcggacg
     1021 gcaacgtgga ctggagagcc atcaacaaca atcggcagaa aatctttcgc tggttacgtg
     1081 gcgagacaac ggcggcgcgc cgaaaaactc aggtgctggc cagtgtgatg aaagccgtgc
     1141 tacccgcaga acggcgggca cgtctggagt cgccgggcga tcccgttttg ctggcaacgc
     1201 tggcggcaaa agaaggggtg gaagcgatta acgctgtaca tctccacttc gcgccagagt
     1261 taactattca ggaaattgac gaagcaatag cggcgctggt agcgacgcga ggagcagtga
     1321 tacgcactgc gcaagaccac catgcatgag cgcctgacca gcgtttaact tataccgagg
     1381 aaagaccgat gttaagacat attgaccgca ttacctggcg taacggctgg cacctgaatg
     1441 gacgcccggc acatgttgca gagatccgcc ccatattcga tggccgcgtc gcagctgcac
     1501 gttctgtatg ggaaaagtac gaagaagaaa aagcgaaact gcgtgagcaa aatctctctg
     1561 gcgctgccta tgaggctggc tgtcgcgttc tctcagaggc tttgggcata tgaacatcct
     1621 cccgttactt gatagaccca tagccttcca gagaagtttt atccgtcttg aaatgggcgt
     1681 gactgccgca ttgtttctgt cgcagttgac gtactggaca aacagaacaa ctgacgacgg
     1741 ctgggtatat aaaacccagg atgagtggga agaggaaaca gggctttcac gatacgagca
     1801 ggagggcgcg cgcaaaaaac tacgtggtct cggcgtcttg ctggaacgta aacagggctt
     1861 gcctgccagg ctgtactaca aaatcgataa tgatgtgttg tgccagctac ttacgtccgc
     1921 atacaaggat gcggaaaaac cacatacagg tgaggggaaa accaccaggc ctgtacgtgg
     1981 aaaaccaaca aacattctta cagagaatac tacagagatt attactgatg gtgaatcggc
     2041 tgacgccgac acccaacaac ctgccgacca gagaataaat tatcaggtga tactcgatac
     2101 ctatcacgag attttgccag agatgccacc agtgaaaatc ctcactgacg gcagaaaaaa
     2161 acaccttcgc actttctgga aaaaattcaa tttcaatgag tcccgttggc gggcctatct
     2221 ggaatttatc ggtggcaatt gtcgctggat gctggaggac aggccaaatg gcaggggagg
     2281 attctggcgg cgtaaaaatc ttgattatct gattaccgaa cgctgctatg tttcggtcaa
     2341 ggaagaacgc gcaaatgata aataacgcga ttgcactgta cagcgttgac gcagaacagg
     2401 ctgttctggg ctgtctgatg ctgaataccg accacgacag aaccaatgcg gtatttgcgt
     2461 tactgaaacc ggaaacgttt tatatcaatg cgcatcaggt tatctaccgg gagatcaaag
     2521 gattatttca agctgataaa ccaactgacc tgataacact gaccgaactg atggaatcga
     2581 aggggctgta tgagcgcgtg gggggattcg catacctggc tgaaatgagt aaggcggcga
     2641 ttccggcctc aatggtcaac tacgcgaaaa ttgtacgtga aaaagccatt cttcgttatg
     2701 ccgtggaaaa gttgaattct tgtctggaga ttatgatcca gcctgcagat atgactgcta
     2761 ctgacaggat caccgccgtt cagcaagtga ttgggcaggt ggccgaacat tcccgtaccg
     2821 ggcataaggg cggtttgcgt ccggcaagtg aagtcgtcga tgactggata gatgaccttg
     2881 agcgccgttt caatgatcca gcacatgcag ccggactaac gctcggaatc gaaagccttg
     2941 atcgcttaat ggcaccaaag caggcgttaa gaggttcatt ggtcgttatt ggtgcccggc
     3001 caaaaatggg caagacagcc gcgtttaata aaattgcggt gcattttgct ctgaatcatc
     3061 gtttgccgac gctggtattt agcctggaaa tgactgacag aagtctcatt gaacgcatgg
     3121 ttgcgcagga agcaaaggtc aattcggaga ttttttatct tggccctaac gatgaatctg
     3181 aattgagtct cgcaatagca aaggcggggg agattgccga atccaacatg atgattgaca
     3241 gcacggcagg tgtaaccctt gcgcatattg tcgctgaatg tcgaaaagtt aaacggatgc
     3301 gtggctcggt tggcctggtg gcaattgact atttgacgct gatgaagacc gaatcggcag
     3361 agcgtaggga tattgcgtat ggcgatatca caaccggttt gaagaacctg gcaaaagagc
     3421 tggattgtgt tgtggtcctg ctgacgcaac tcaaccgaaa gcttgaagaa cgtgccgata
     3481 agcggcctaa cccgagcgac agtaaagata ccgggcagat cgaacaagat tgcgatgtct
     3541 ggattggcct ctatcgtgat gctgtttata acgaaaatgc cgacccaaat ctcatggaaa
     3601 tgttgctacg tctgaaccgc gaaggaccat cgggaacagc ctatgccctg atgaaaaatg
     3661 gctcagttat tgatatcagc gatgaggagg tttatcgcct taccaacgac cgctcagaaa
     3721 aaaataaacg ttattcccgt agcgataatt ctcgcacaaa tgaattttaa ccacgcctga
     3781 ccagcgtgaa ataaccgagg aaagaccaat gaccaccact ccaggcaaat tagagtaccc
     3841 gtcggacaaa ggacacatag acgacggtaa aaactatctc gacgtcattt tgtggaatat
     3901 gaacgtcggg ccacgtgcgc gcactcgcgc ggtttttgtg ccaagaccta aagcaggcaa
     3961 tttttcaacc cctgctaagc ctgcccgtca ggcatccgta gccgcagcgc cagcagtgaa
     4021 acgtaagggc aaaacgcaca ccgggatcgc gattcgcaga aatggtgagc ggcaagtgaa
     4081 actccacgaa acagcgacaa cctggtgtgc ctcaccgcat gaaacttacg acaagataac
     4141 cgggcagcgc attggcgcgc ctggtcgctg ccgcctgctg ctgagttcca tcactccgat
     4201 agcaaagaaa ggggcgtgat atggccgggc aatcagatta cctgccgccc ggcttaccac
     4261 acaaccgcgc caaatggccc caggaatacc agcttaaaga gcactacgac atgcgagcgg
     4321 cggcgctgat ccgccaactc tttgagaaac gtattccgag gggaagcgtg attgagcaaa
     4381 tcggaatgac gccagatacg taccgggaat ttttcagaga gcgtctgaac tactggagag
     4441 gggtgatgga acaatgaaat acaaacggtg ggtgcgtgcg gaagtcgtaa tcatcaaaca
     4501 atgtgcgggc agcatgacag ttgaacgtat agggcagctt attggcagaa ccggtgcagc
     4561 ggtacgcaca aaagcgcgcg agctgaaaat ctgtatgtat ctgcggggta attatcacca
     4621 gtcagtgaaa tacctccagg aagatatcga gctggcaagg gaattacatc agtcgggtat
     4681 taatcgccag gatatcgcag aaaaactcga aatgccgatc ggagcggtga atcagtttgt
     4741 ttattttgag cggagaattt catgaaagaa ctttttcttg catttgtgcc ccggtttatt
     4801 aatgaccaga tcgcactgac tgataatggt gaacaatatg aaattgcctg cagcatggtg
     4861 gatgtgaatc ctggcgaacg gtatgacgcg atgtgtgacc tgaaaatatt tacctggctg
     4921 ggttgggcta ttccgtgtgg agaaccaacc aatattcgtc cgtttgagag cagggaggct
     4981 gtatgagtga attgaaaata cgtcgcaagg caatagcacg cgttaaaaat ctattaccag
     5041 tgcctgtcaa atatcgtttt tgtggtggga atgtacggat tggtacggat gtatggtgat
     5101 tgcggagtga cgtaaaacga atcgttgtgg gtgtaatatc gtcaatatca ttggtttccc
     5161 ggagggaaag gacatgtttg gcgataaact ggagttacca cggaacgggc ggatagtgct
     5221 ctatatttca gattacaaag taacccgggc tgaggtgttg gaaccggaaa aacatctggt
     5281 cacgttaccg gacattattg agttgtataa gcgggtcgga tatgtggact tgcatcgcga
     5341 tgatgttccc gttgagtgta tggaatgtga acaccggagg tttgaagttg attgaattga
     5401 cttagaaaaa gtccggggct atagtttccg cgcagccgca aaatcggttg ccgggattgg
     5461 cgtcccggat atctaagtga cgcatagccg cgttagcggt ttttttatgt gttaggcacg
     5521 gccacattcg cattatggtg ggctgtgtgg gggcttctgt ggaagcgccg ggttcactta
     5581 gccggttacg ccaaccctgc acagctcacc accagatgat tggcgtcgct ggtggtgatg
     5641 aaaaaaacac taagtgaggc cactgcgatg acagtccaaa tatctgcgga atccctttct
     5701 ccgctacatc ataaccaact tcccgtcatc actactgaat tgcttgccag tttgtatggc
     5761 acggaagtaa atggtatcca gcaaaacttc aagcgcaaca tcgccagatt tgtcgtagga
     5821 aagcattttt ttaagctgga aggtaatgaa ttacgcgact tcaaaaacag actgacagat
     5881 agtcagtcag ttgctaaaca tacccgatcc ctcattctct ggacagaacg cggcgcagct
     5941 cgccatgcca aaatgctgga aacagaacag gcctgggaag ttttcgaaaa gctggaagat
     6001 tgttatttta gccagcgtcc agagaggcgg agtacaacta ccgatgaccg tactcccttg
     6061 cgtgatgccg ttaatatact ggtcggcaag aaaggcatga tgtatcccga tgcctacacc
     6121 atgattcatc aacgcttcgc cgtctctcac atagaacaac tgtcacagac gcaaatgtta
     6181 gaggcgattg aatacatcca ctgcctgcta ctcgatgaaa atcacccaac cattccagat
     6241 ttttctttta tcaccactat caaaaatgga aaagtgaccg ggatgcgcca tgttgccaaa
     6301 ggcgaacatc tgatgacctt tgacgctttc aaagagatcg ctgagcgggc agggtatctg
     6361 gtgatccaca gcgacaatct gcgaagtatg acactggata aattgatggt aatggggaaa
     6421 aagtcggcta tatccgttgc taattcagca ttttgacagg ttgtttgggg cggaaatact
     6481 ctatttgcgc ttaaaaaggt atttgaccac gaccagcacg agaccgaata cctctgtcaa
     6541 agtaccgccc atataaaaca gttacatatg cacttgatga ctaagctggc accaggttaa
     6601 cacctggcgc cagcttgaag gagacttcag ttattggttt ctgaggaaag cgattcttga
     6661 aagggtcatt tgcgtctggc agtcgaccat tttcttgact tcagcatctg ttccctgcat
     6721 tgaaacttta ccgcacatag catccttagt tttgatccac tgacgctgag aaggcagcaa
     6781 atcttttttc ttcgccgggg ttaacttgct ccagacggta ctcaaatcag agtcggcatt
     6841 cgcaaatgcc attcgggact gatcaaggtt gtcagctttt tgcggctgaa gttgtgcctg
     6901 tctctctatt tgcttctccg cctcatactt agcctgttct tgcgccctga gttgcacctg
     6961 ttgttccgct tcaatttgac tctgttgggc atccttagcc tgctggattt tctgctgctc
     7021 aacgatcggg gtgataatgg aaagcgatgt cagtaaagcg gcgcccactg atatcggatt
     7081 atcagtagag gtttttacaa aaacgttttt ctgatcgtcg gtcgcctgca cggtgtaggt
     7141 gatacgtttt gaaaaggcgt ttgcgttgtt ctccaaaaac aggctttcca tttgcttatc
     7201 gagattacga ttaaaattct ttctgtaagc atctgaaagc tggacgtact cgttcgcaga
     7261 tagagtcatc gtcacggtcc cttcacaagt tttcattgtg ctgcccgtgt cacttgatgt
     7321 tgtggagatc tcagagatgg ctagtttgat cttgtccagt gtgcttcgtt tggtctgatt
     7381 agtgacatca gggtatttat cgacctgttc agagagtcct tcataagcag atttttttaa
     7441 taaatccatg agagctgact gggttatttc cgaagaacaa ccgatctcat cttttttgtt
     7501 atcacagcct gtaagggcaa tggcgagtaa gagtactgag tattttaatc tcatgaattc
     7561 cctttagagt aaggattggt ttttaagacg cggtctgtaa tcagtcccga gagctacagt
     7621 aaacaacgct gagcactgaa cgcatcacag gtaaggtaaa aggtgatatc ggcaaaggct
     7681 gtgaaacctt taattcaaca gatgggaacg gtatgcgcag gatcctgtaa cgacgctccc
     7741 aaaaccggaa acctgtaagg catgttttcg ctgctgaact taatatacga acctgcacta
     7801 tcatgaacat attttatatc gttatacccc gagtgattgt gcccggcaat ggatagtgtc
     7861 ctggaggaac tatttctact gtaaaaggta gatatttaat ttcagttttg aattattccc
     7921 tgctgttaat aacaatggct gtatatggca ccgagtaggc attttttcgc ttactgaagg
     7981 gcagctgtga gcgaggaaca gact
//
LOCUS       DAFGPF010000176         7940 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFGPF010000176 DAFGPF010000000
VERSION     DAFGPF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7940
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.176"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(3..89)
                     /locus_tag="LSX49_004792"
     tRNA            complement(3..89)
                     /locus_tag="LSX49_004792"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53..55),aa:Leu,seq:cag)
     gene            complement(289..1320)
                     /gene="rsmC"
                     /locus_tag="LSX49_004793"
     CDS             complement(289..1320)
                     /gene="rsmC"
                     /locus_tag="LSX49_004793"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HBL7171072.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLNRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDANKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANSVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
     gene            1423..1836
                     /gene="holD"
                     /locus_tag="LSX49_004794"
     CDS             1423..1836
                     /gene="holD"
                     /locus_tag="LSX49_004794"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HBL7171073.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPPHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VTSPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            1805..2251
                     /gene="rimI"
                     /locus_tag="LSX49_004795"
     CDS             1805..2251
                     /gene="rimI"
                     /locus_tag="LSX49_004795"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL7171074.1"
                     /translation="MNTISSLETTDLPAAFHIEQRAHTFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            2266..2943
                     /gene="yjjG"
                     /locus_tag="LSX49_004796"
     CDS             2266..2943
                     /gene="yjjG"
                     /locus_tag="LSX49_004796"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HBL7171075.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGVITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHHREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            3034..4623
                     /gene="prfC"
                     /locus_tag="LSX49_004797"
     CDS             3034..4623
                     /gene="prfC"
                     /locus_tag="LSX49_004797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBL7171076.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWA
                     PAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     SRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSM
                     VNLRLAQERYPDVQFHQTREH"
     gene            5016..5621
                     /gene="osmY"
                     /locus_tag="LSX49_004798"
     CDS             5016..5621
                     /gene="osmY"
                     /locus_tag="LSX49_004798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HBL7171077.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            5748..5909
                     /locus_tag="LSX49_004799"
     CDS             5748..5909
                     /locus_tag="LSX49_004799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HBL7171078.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            6031..7104
                     /locus_tag="LSX49_004800"
     CDS             6031..7104
                     /locus_tag="LSX49_004800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HBL7171079.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAFICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTCHLVPVVTPESIVIPPAPVAND
                     TLVAEVSDAPQANDPTFNNEDLA"
     gene            7101..7883
                     /locus_tag="LSX49_004801"
     CDS             7101..7883
                     /locus_tag="LSX49_004801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL7171080.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDL
                     FGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLPCTGVVHGFS
                     GSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     QPNRPEQAVRVFDVLCELRPEPEDEIAEVLLNNTYALFSVSG"
BASE COUNT         1908 a         2055 c         2148 g         1829 t
ORIGIN      
        1 tttggtgcga ggggggggac ttgaaccccc acgtccgtaa ggacactaac acctgaagct
       61 agcgcgtcta ccaattccgc caccttcgca taccatcaat tcttaaaaag aattgctacc
      121 acggaggcgc attctagtgg ttttcagctt ttcgtcaata gttaattatc gacagaggtg
      181 taattgctgg aaaaatgtcc atcagcggat tgtggataat tcgtttgtcg gtcagataag
      241 gcgtgtacgc cgcatccaac acggtatgcg gcgacagata tcagatactt aacctttctt
      301 cgcctggcgg gtcataatgg cgcgatacac cttgaagcgc ccggtttgcg caatcacttc
      361 gtggaaacca aatgtctcat ccagcacgtc cgggtaaggc aggaaggcgt tcgctacaat
      421 tcgcagctcg ccgccgctat taagatgacg caccgcgccg cgaatcagcg tttgcgccgc
      481 atccaggctg gtttgcatcc catcgtggaa cggcgggttg gagatgatca tatcaaaacg
      541 acctttcacc tcggaaaaga cgttgctggc aaagacttca ccttcaacac tgttggcagc
      601 aagtgttgcg cgactggctt ctaccgctgg tgcagaaaca tcacacagag tgaggcggat
      661 cttcggtgaa tggcgcgcaa aagcaacgga aagaacgcct gcgccgcagc cgacatccag
      721 cactttacct ttcgtgtgcg gggttagcgt cgagagcaac aactgactgc cgacatccag
      781 accgtcgcgg ctaaacacgc ccggcagcgt tttgaccgtc aagccatcga cgctgtattc
      841 gccccagaat ttattggcat caaataccgg ctgcttttcc agacgaccaa aatagaggcc
      901 gcagcgacgg gcgctgtcta ccttattcaa cggcgcataa tcggccagca tctgctcggc
      961 gctgcgcacg ccgctgcggt tctcgccaac gacaaaaata tccgtgccca ccggaagcag
     1021 agaaagtaaa ttcatcaact ggaactgggc ttccggttta ttcttcggcc agtagtaaat
     1081 caaagtatcg caatcagcga catcatccgc cgtggcgacc aggctaaaac gggcgttatc
     1141 ccccatctgg cggtttaaca cctgccagtg gtggaattgc tgggtatgag cacggctggc
     1201 cgcggtatct aaacgcgcgg gcaggtcatc ctgtaagtct ccggcaaaca gaatacggct
     1261 ttgttcgaaa tcatcactgt gacgcagcaa gacttcactt gccggggtaa atgcagacat
     1321 ggaatgctcc tcaattgata ctggcggcga ttatagccat atgttggcgc ggtatcgacg
     1381 aatttgctat atttgcgccc ctgacaacag gagcgattcg ctatgacatc ccgacgagac
     1441 tggcagttac agcaactggg cattacccag tggtcgctgc gtcgccctgg cgcgttgcag
     1501 ggggagattg ccattgcgat cccgccacac gtccgtctgg tgatggtggc aaacgatctt
     1561 cccgccctga ccgatcctct ggtgagcgat gttctgcgtg cgttaaccgt cagccccgat
     1621 caagtgctgc aactgacgcc agaaaaaatc gcgatgctgc cgcaaggcag ccgctgcaac
     1681 agctggcggt tgggtactga cgaaccgcta tcactggaag gcgctcaggt gacatcaccg
     1741 gcgctcaccg aattacgggc aaacccaacg gcacgcgccg cgttatggca acaaatttgc
     1801 acatatgaac acgatttctt ccctcgaaac gactgattta ccagcggctt tccacattga
     1861 acaacgcgcc cacacctttc cgtggagtga aaaaaccttt gccagcaacc agggcgagcg
     1921 ctatctcaac tttcagttaa cgcaaaacgg caaaatggcg gcgtttgcga ttacgcaagt
     1981 ggtgctggat gaagctacat tgttcaatat tgcggtcgat cctgactatc agcgtcaggg
     2041 actgggaagg gcgctgctgg aacatctgat cgacgaactg gaaaaacgcg gcgtggcgac
     2101 gctatggctg gaagtccgtg cctcaaatgc tgccgccatt gccctgtacg aaagtttagg
     2161 ctttaacgag gcgacgattc gccgcaatta ctaccccacc acggacggtc gcgaagacgc
     2221 catcatcatg gcgttaccaa tcagtatgta agacaaggtg gaataatgaa gtgggactgg
     2281 attttctttg atgccgatga aacgctgttt acctttgact cattcaccgg cctgcagcgg
     2341 atgtttcttg attacagcgt cacctttacc gctgaagatt ttcaggacta tcaggccgtt
     2401 aacaagccac tgtgggtgga ttatcaaaac ggcgtgatca cttcattaca gcttcagcac
     2461 gggcggtttg agagctgggc cgaacggctg aacgtcgaac cgggtaaact caacgaggcc
     2521 tttattaatg cgatggcgga aatctgtacg ccgttgccgg gggcggtttc cctgcttaac
     2581 gccattcgtg gcaacgctaa aatcggcatc atcaccaacg gctttagcgc cttgcagcaa
     2641 gtgcgtctgg aacgcacggg cctgcgtgat tacttcgatt tgctggtgat ttccgaagaa
     2701 gttggcgttg ccaaaccgaa taagaaaatt ttcgattatg cgctggaaca ggcgggcaat
     2761 cctgaccgtt cacgcgtgct gatggttggc gacactgccg agtccgatat tctcggtggc
     2821 atcaacgccg ggcttgcgac ctgctggctg aatgcgcacc atcgcgagca accagaaggc
     2881 atcgcgccca cctggaccgt ttcttcgttg cacgaactgg agcagctcct gtgtaaacac
     2941 tgattgcctc ccccccgttg atgggtaaaa tagccgcaat ttttcgtttt caacaagcgc
     3001 ggcgcgatgc cgcttactca agaagaaaga attatgacgt tgtctcctta tttgcaagag
     3061 gtggcgaagc gccgcacttt tgccattatt tctcacccgg acgccggtaa gactaccatc
     3121 accgagaagg tgctgctgtt cggacaggcc attcagaccg ccggtacagt aaaaggccgt
     3181 ggttccaacc agcacgctaa gtcggactgg atggagatgg aaaagcagcg tgggatctcc
     3241 attactacgt ctgtgatgca gtttccgtat cacgattgcc tggttaacct gctcgacacc
     3301 ccggggcacg aagacttctc ggaagatacc tatcgtaccc tgacggcggt ggactgctgt
     3361 ctgatggtta tcgacgccgc aaaaggtgtt gaagatcgta cccgcaagct gatggaagtt
     3421 acccgtctgc gcgacacgcc gatcctcacc tttatgaaca aacttgaccg tgatatccgc
     3481 gacccgatgg aactgctcga tgaagttgag aacgagctga aaatcggctg cgcaccgatc
     3541 acctggccga tcggctgcgg caagctgttt aaaggcgttt accaccttta taaagacgaa
     3601 acctatctct atcagagcgg taaaggccac accattcagg aagtccgcat tgttaaaggg
     3661 ctgaataacc cggatctcga tgcagcggtc ggtgaagatc tggcacagca gctgcgtgac
     3721 gaactggaac tggtgaaagg cgcgtctaat gagttcgaca aagagctgtt ccttgcgggc
     3781 gaaatcactc cggtattctt cggtactgcg ctgggtaact tcggtgtcga tcatatgctg
     3841 gatggcctgg tggagtgggc tcctgcgccg atgccgcgtc agactgatac ccgtaccgta
     3901 gaggcgagcg aagacaaatt taccggcttc gtatttaaaa ttcaggccaa catggacccg
     3961 aaacaccgcg accgcgtggc gtttatgcgc gtggtatccg gtaaatatga aaaaggcatg
     4021 aagctgcgcc aggtgcgcac tgcgaaagat gtggtgatct ccgacgcgct gacctttatg
     4081 gcaggtgacc gttcgcacgt tgaagaagca tatccgggcg atatcctcgg cctgcacaac
     4141 cacggcacca ttcagattgg cgacaccttt acccagggtg agatgatgaa gttcaccggt
     4201 attccgaact tcgcgccaga actgttccgt cgcatccgcc tgaaagatcc gctgaagcaa
     4261 aaacagctgc tcaaagggct ggtacagctt tccgaagagg gcgcggtgca ggtgttccgt
     4321 ccaatctcca acaacgatct gatcgttggt gcggttggtg tgctgcagtt tgatgtggtg
     4381 gtatcgcgcc tgaagagcga atacaacgtt gaagcagtat atgaatcagt caacgttgcc
     4441 accgcccgct gggtagaatg tgcagacgcg aagaaattcg aagagttcaa gcgtaagaac
     4501 gaaagccaac tggcgcttga tggcggcgat aacctcgctt acatcgctac cagcatggtc
     4561 aacctgcgcc tggcgcagga acgttatccg gacgttcagt tccaccagac ccgcgagcat
     4621 taattcttgc ctccagggcg cggtagccgc tgcgccctgt caatttccct tccttattag
     4681 ccgcttacgg aatgttctta aaacattcac ttttgcttat gttttcgatg atattccgag
     4741 cggtttcaaa attgtgatct atatttaaca aagtaatgac atttctgacg gcgttaaata
     4801 ccgttcaatg cgtagatatc agtatctaaa gccgtagatt gtcattctac cgatattaat
     4861 aactgattca gaggctgtaa tggtcgttat tcatcaccca tcgcttttgt gatggcgacc
     4921 attgacttct gtagagggtg aagtctctcc ctattcagca atgcaacctc gtgttgccag
     4981 gctcaaatta cgagcaaact tacaggaata aatcgatgac tatgacaaga ctgaagattt
     5041 cgaaaactct gctggctgta atgttgacct ctgccgtcgc gacaggctct gcctacgcgg
     5101 aaaacaacgc gcagactacc aatgaaagcg cagggcaaaa agtcgatagc tctatgaata
     5161 aagtcggtaa tttcatggat gacagcgcca tcaccgcgaa agtgaaggcg gccctggtgg
     5221 atcatgacaa catcaagagc accgatatct ctgtcaaaac cgatcaaaaa gtcgtgaccc
     5281 tgagcggttt cgttgaaagc caggctcagg ccgaagaggc agtgaaagtg gcgaaaggcg
     5341 ttgaaggggt gacctctgtc agcgacaaac tgcacgttcg cgacgctaaa gaaggctctg
     5401 tgaagggcta cgcgggtgac accgccacca ccagtgaaat caaagccaaa ctgctggcgg
     5461 acgatatcgt cccttcccgt catgtgaaag ttgaaaccac cgacggcgtg gttcagctct
     5521 ccggtaccgt cgattcccag gcacagagcg accgtgctga aagtatcgcc aaagcggtag
     5581 atggtgtgaa aagcgttaaa aatgatctga aaactaagta attcgtcgta attcgtcctc
     5641 ccgaactttg tcgggaggcg cgatgtgcac cacactaaaa atatcgcatt gagtgatttt
     5701 cacgctcata tcaagcggtg acattaacta tggtaaagga gacgcttatg tttcgttggg
     5761 gcatcatatt tctggttatc gcgttaatcg ccgccgcact tgggtttggt ggtctggccg
     5821 gtaccgctgc aggcgcagct aaaattgtct ttgtcgtcgg gattattctg ttcctggtga
     5881 gtttgttcat gggccgaaaa cgaccctaga tttcagatca ttaagaaaat tttatccaaa
     5941 gccagtccag cggactggct tttgcggttt tagcgaataa taaattgcgt tactttgtca
     6001 ttctttcaca acaaaaacag gaaggcagag gtggggcagc gaatacctgt aacgcttggt
     6061 aatattgcgc cgttgtcgct aaggccgttc cagcctggac gaatagctct ggtgtgcgaa
     6121 ggcggcggac agcgtggaat tttcacggct ggcgtgctgg atgagtttat gcgcgcgcag
     6181 tttaatcctt tcgatcttta tctcggcaca tctgccgggg cgcagaacct ctcggcgttt
     6241 atctgcaatc agcccggtta cgcgcgcaaa gtcatcatgc gctataccac aaaacgcgaa
     6301 tttttcgatc cattgcgctt tgtccgtgga ggaaatctta tcgatctcga ctggctggtg
     6361 gaggccaccg caagccagat gccgttgcaa atggataccg ccgcgcggtt gtttgacagc
     6421 ggcaaatcgt tttatatgtg cgcctgtcgt caggatgact acgcgcctaa ttacttttta
     6481 ccaaccaaac aaaactggct ggatgtgatt cgcgcctcca gtgcgatacc tggcttttat
     6541 cgtagcggag tgtcgctgga aggcattaac tacctggatg gcgggatcag tgatgcgatt
     6601 ccggttaaag aggcggcaag gcagggcgct aaaacgttgg tcgtcatccg cactgtgccg
     6661 tcacaaatgt actacacgcc gcagtggttc aaacgcatgg aacgctggct gggtgacagt
     6721 agcctgcagc cgctggtcaa tctggtgcag catcatgaaa ccagctatcg tgacattcag
     6781 caatttattg agaaaccacc gggcaagctg cggatattcg aaatttatcc accgaagcca
     6841 ttacatagta tcgcgcttgg cagtcggatt ccggcgctgc gtgaagacta taaacttggg
     6901 cgtttatgcg gtcgttattt cctcgccacg gttggcaagc tattaactga aaaagcgccg
     6961 cttacctgcc atctggtgcc agtggtgacg ccggaatcga tcgttattcc gcctgcgcca
     7021 gtcgccaacg atacgctggt tgccgaagtg agcgatgctc cgcaggcgaa cgacccgaca
     7081 tttaacaatg aggatctggc ttgatttgcc gttttatcga tacccactgc cattttgatt
     7141 tcccgccgtt tagtggcgat gaagaggcca gcctgcaacg cgcggcacaa gcgggcgtag
     7201 gcaagatcat tgttccggcg acagaggcgg aaaattttgc ccgcgtgcag gcgttagcgg
     7261 aaaaatatca accgctgtat gccgcattgg ggttgcatcc ggggatgttg gaaaaacata
     7321 gcgatgtgtc tcttgatcag ctacagcagg cgctggaaag gcgtccggcg aaggtggtgg
     7381 cggtggggga gatcggtctg gatctcttcg gcgacgatcc gcaatttgag aggcagcagt
     7441 ggttactcga cgaacagctg aaactggcga aacgctacga tctgccggtg atccttcatt
     7501 cccggcgtac acacgacaaa ctggcgatgc atcttaaacg tcacgattta ccgtgcactg
     7561 gcgtggttca cggtttttcc ggcagcctgc aacaggccga gcggtttgta cagctgggct
     7621 acaaaatcgg cgtaggcggt actatcacct atccacgcgc cagtaaaacc cgcgatgtca
     7681 tcgcaaaatt accgctggca tcgttgttgc tggaaaccga cgcgccggat atgccgctca
     7741 acggctttca ggggcagcct aaccgaccgg aacaggctgt gcgggtgttt gacgtgcttt
     7801 gcgagttgcg cccggaacca gaagatgaga ttgccgaagt gttgcttaat aatacgtatg
     7861 cgttgtttag cgttagtggg tagtttaccc ttcgtaggca gcatccggca gtcggcgcat
     7921 aatgcctgat gcgacgcttg
//
LOCUS       DAFGPF010000177         7878 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFGPF010000177 DAFGPF010000000
VERSION     DAFGPF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7878
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.177"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            506..1255
                     /locus_tag="LSX49_004802"
     CDS             506..1255
                     /locus_tag="LSX49_004802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter beta domain-containing
                     protein"
                     /protein_id="HBL7171081.1"
                     /translation="MSKKYQPLLITHYMSTWVTITEAVEITTKAIKQKITPSDIYRHA
                     LSGNILLSIYFQSPVILKKIQTFNGKIKFRQFVGDLLDKLCMLDSDGFIYGQNLRLCT
                     EARYICPVQQIIDTPLLRKLNQFRTFVRNVRPGDELDVQAQVSEKNLTPPPGNSSGNL
                     EQQIASTSQLIGSLLAEDMNSEQAANIARGWASSQASGVMTDWLSRFGTARITLGVDE
                     DFSLKNSRDGNPRKWRFDATNSELCAERHEC"
     gene            1182..3304
                     /locus_tag="LSX49_004803"
                     /pseudo
     CDS             1182..3304
                     /locus_tag="LSX49_004803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416485.4"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
     gene            complement(3474..4526)
                     /locus_tag="LSX49_004804"
     CDS             complement(3474..4526)
                     /locus_tag="LSX49_004804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HBL7171082.1"
                     /translation="MFLVSLLRRIAFSYYDYKTYNFNIEKTDFVVIHIPDQIGDAMAI
                     FPVIRALELHKIKHLLIVTSTINLEVFNALKLEQTKLTLVTMTMQDHATLKEIKDLAK
                     NITLQYGTPDLCIEAMRKKNLKTMIFISQLKAKTNFQVVGLTMKCYSPLCKNASRMDQ
                     NLRAPVPMTWAFMMREAGFPAVRSIYELPLSDDVLDEVREEMRSLGSYIALNLEGSSQ
                     ERTFSLSIAENLIAKIQSETDIPIVIVYGPKGEDKARALVDCYNNVYRLSLSPSIKRS
                     AAIIKDAYIAITPDTSILHMASAYNTPVVAIYADYKTRWPAMADVSESVVVGQKIDNI
                     SLDEFAKALKSVLARI"
     gene            4841..6157
                     /gene="shiA"
                     /locus_tag="LSX49_004805"
     CDS             4841..6157
                     /gene="shiA"
                     /locus_tag="LSX49_004805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HBL7171083.1"
                     /translation="MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     MMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHNQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGALIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDNQRS"
     gene            6259..7713
                     /gene="amn"
                     /locus_tag="LSX49_004806"
     CDS             6259..7713
                     /gene="amn"
                     /locus_tag="LSX49_004806"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HBL7171084.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGKYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
BASE COUNT         2172 a         1840 c         1743 g         2123 t
ORIGIN      
        1 ttcctttctc tccttatact aaagaaataa tcatatcaaa ataaaaattc acaacagtgc
       61 aacattaaaa aatacaacca acaaacaatc ctatatacaa ggcacatctc cagaatataa
      121 aagcacagac aaacaaccta aaaaaacaac cccatacata taaattattt tataggtaaa
      181 atagattata tattctcata gctaccataa actatactag cctgaactat atttattctg
      241 ctacaatcaa tgcatacata acacaaatat cactcaggta cactactcaa accacgctgg
      301 gatttttcct caagttataa tcatcacccc gaaaatcatt cggcatttac tcattaaata
      361 gtcaccccat aggcctgtac atgtttactc agaaatatac atccttttct ctgtcataaa
      421 ccctctgatt aatcataaat aaatacttgt gacaccaatc tttttcctta acggaacgaa
      481 ttgttgtgta gaaggagata atattatgtc aaaaaaatat cagccattgc ttataactca
      541 ttatatgtca acatgggtca ctataacgga agcagttgag atcactacca aagccataaa
      601 acaaaaaatt actcctagcg atatttatcg tcatgccttg agtggcaaca tcctactatc
      661 gatctatttc cagtctcctg tgatacttaa gaagatacaa acttttaatg gaaaaataaa
      721 attcaggcag tttgtgggag acctacttga taaactatgc atgcttgaca gtgacggttt
      781 tatttatggt caaaatttaa gactctgtac agaagccaga tatatttgtc ctgtgcaaca
      841 aattatagat acccccctgt tacgcaaact caaccagttt cgtacgtttg ttcgtaatgt
      901 ccgcccgggt gatgaactgg atgtccaggc acaagttagt gaaaaaaatt taaccccgcc
      961 gccgggtaac agcagtggca accttgagca acagatagcc agtacttcac agctaattgg
     1021 atctctgctc gccgaagata tgaacagcga gcaagcggca aacatagcac gtggatgggc
     1081 ctcttctcag gcttcagggg taatgacaga ctggttaagc cgcttcggta ccgcaagaat
     1141 cacgctgggc gtggatgaag atttcagcct gaagaactcc cgtgacggca accctcgaaa
     1201 atggcgattc gatgcaacaa acagtgaact atgtgccgaa cgtcacgaat gctgaaatca
     1261 cgctggcagc ctcgaaggat ccggtgattg ccgacaataa cgatctcacg acactaacag
     1321 caccgtcgct gatacagagg gcaatgcgat agccaacact gaggtaacat ttactctacc
     1381 ggaagatgtg aaggcgaact tcacgctgag cgatggcgac aaagcggtta ctgatgccga
     1441 tggcaaagcg aaagtcacgc tgaaaggtac aaaagcaggc gctcataccg tgacagcatc
     1501 gatggttggc ggtaagagtg agcagttggt ggtgaacttt actgcggata cgctcactgc
     1561 gcaggttaat cttaacgtta ccgaggacaa tttcatcgcc aataacattg gaatgaccag
     1621 gctacaagca acagtgactg atggaaacgg caacccagta gaaggtataa aagttaattt
     1681 ccgtggaacc tccgtcacgc taagcagcac cagcgttgaa acggatgatc aggtttttgc
     1741 tgaaattctt gtgacaagca ccgaggtcgg actaaaaaca gtttcagcct ctctggcaga
     1801 taaacctact gaagtcatct cgcgattact gaatgccaag gtagatgtta attctgcgac
     1861 gattaccagt caggagatac ctgaaggtca ggtcatggtc gcacaagaca tagcagttaa
     1921 agctcacgtt aacgaccagt ttggcaaccc ggtgacgcat caacccgcga cattcagtgc
     1981 agcgccatcc tcgcaaatga tcatcagcca gaacacggtc tctactaata cgcagggagt
     2041 agccgaggtc accatgacgt ctgaaagaaa cggctcgtat actgtaaaag catccctagc
     2101 gaatggagct tcacttgaga aacaactgga ggctattgat gaaaaactga cactcacgtc
     2161 cagtccgctt atcggtgtca atgctcctaa aggcgctact ctgacggcaa cgctaacctc
     2221 tgcaaatggc actccagtgg agggtcaggt catcaacttt agcgtaacgc tagaaggtgc
     2281 gacgttaagt ggcggaaaag tgagaaccaa ctcttcagat caggctccag tcgttctgac
     2341 cagcaataaa gtcggtacat atacggtgac tgcatcgttc cataacggcg tcacaataca
     2401 gacacagaca accgtgaagg ttactggcaa cccaagcacc gcacatgttg ctagctttat
     2461 cgctgatccg tcgactatcg ccgccaccaa cagtgattta agtaccttaa aggcaacggt
     2521 tgaggatggc agtggtaacc tgatcgaagg tctcactgtg tacttcgcct taaaaagcgg
     2581 ctccaccaca ttaacgtcat taacagccgt gaccgatcaa aacggaatcg cgacaacaaa
     2641 cgtgagatga gcgataacag ggagcgtcac tgtaagcgca gtcataagcg caggtggaat
     2701 gcaaacagta gatatatcgc tagtggcagg cccagcagac gcctcgcagt ccatccttaa
     2761 gaacaaccag tcatcactga aaggggactt taccgatagt gctgagctac atcttgttct
     2821 gcacgatata tcaggcaatc cgatcaaagt ttcttaaggg atagaatttg tgcaatcagg
     2881 tacaaacgtg ccctatatga aaattagcgc aattgattac agtcaaaata tcaacggtga
     2941 ttacaaagct actgttacag gaggcggaga gggtatcgca acgctgatcc ccgtattgaa
     3001 tggtgttcat caggcgggtc tgagtaccac gatagaattc attagcgcgg aaaccagacc
     3061 aatgacgggt acagtgtcag tgaatagtgc aaacctaccg acagcttcat tcccttcgca
     3121 gggatttacc ggggcgtatt atcagttgaa taatgacaac tttgcaccag gaaaaacggc
     3181 ggctgattat tcgttttcaa gctcggcctc ctgggtaggc gttgatgcta ctggtaaagt
     3241 gacattcaaa aatgacggtg atagcaatac tgtaataatc acagcgcccc caagatccgg
     3301 tggtgctatt taccaaacag ttcctcctga atcgcgttcg gtgtgactat gatcattttc
     3361 ggtgagtatt gctttgatcc aaaggctggt tttctgtgat gattgaccag cctcagagta
     3421 ttgatgacac caccgttcat aacagatcgg cattactatg cataagtact gcctcaaatt
     3481 ctcgccaaaa cactttttaa tgcctttgcg aattcatcca gacttatatt gtcaattttt
     3541 tgcccaacga cgactgactc cgaaacatcg gccattgcgg gccatcgcgt tttgtaatca
     3601 gcataaattg caacaacagg ggtattatag gcacttgcca tatgtaatat tgaggtgtca
     3661 ggagttattg caatataagc atcttttatg attgctgctg aacgtttaat cgagggtgat
     3721 aaggataaac ggtagacatt attataacaa tccactaatg ccctggcttt atcttcccct
     3781 ttgggtccat aaacgatcac tattggaata tctgtttcac tttgaatttt tgctattaga
     3841 ttttctgcaa tcgataatga aaatgtacgt tcctgcgagc taccttctaa attgagcgca
     3901 atgtaagatc ctaacgatcg catttcctcg cgtacctcat cgagtacatc atcgcttaat
     3961 ggcaattcat atattgacct gactgccgga aaacccgcct cacgcatcat aaatgcccat
     4021 gtcatgggta caggagcccg gagattctga tccatccggg acgcgttctt acacaaaggg
     4081 gaatagcact tcatggttaa accgacgacc tggaaattcg tttttgcttt caactgactg
     4141 ataaatatca tcgttttcag gttcttttta cgcatcgcct ctatacaaag atccggcgta
     4201 ccatattgca gtgttatgtt cttcgctaaa tcttttattt cttttaatgt tgcgtgatcc
     4261 tgcatagtca ttgtgactaa tgttaattta gtctgttcaa gtttgagcgc attaaagact
     4321 tctaaattaa ttgtcgacgt aacaattaat agatgcttaa ttttatgcaa ttcaagcgcc
     4381 cgaataacag gaaagatggc catagcatcg ccaatctgat cgggaatatg tatgacaaca
     4441 aagtctgttt tttcaatatt aaaattataa gttttataat cgtagtaact aaatgcaata
     4501 cgtctcaaca atgatactaa aaacataact aacctcgcct ccctactggt tataatgcaa
     4561 tgcagtctat cagaatcatc agggtgcaat tttgtgcata tgcggacttt tatgtttcat
     4621 atctcgaacc tgtgggccct ctgcttaatc cttaaacaac accagcaact cctgcgcttt
     4681 catcttccat cgaatttttc atgttgccgc taatcagcca taaaatcatt tgcagatgcg
     4741 ctctgtcgag gtagtctcat aaggttcgtt tatagatcga cggcaatgtg agttaccttt
     4801 tccatactaa ttataaaaag acagtacaaa caggatcatt atggactcca cgctcatctc
     4861 cactcgtccc gatgaaggga cgctttcgtt aagtcgcgcc cgacgagctg cgttaggcag
     4921 tttcgctggt gccgtcgtcg actggtatga ttttctactc tatggcatta ccgccgcact
     4981 ggtgtttaat cgcgagtttt tcccgcaagt aagcccggcg atgggaacgc tcgccgcatt
     5041 tgccaccttt ggtgtcggct tccttttccg accgctcggc ggtgtcattt tcggtcactt
     5101 tggcgaccga ctgggacgta agcgcatgtt aatgctgacc gtctggatga tgggcatcgc
     5161 gacagcctta attggtattc ttccttcatt ctcgaccatt gggtggtggg cacctatttt
     5221 gctggtgaca ctgcgtgcca ttcagggatt tgccgtcggc ggcgaatggg gaggcgcagc
     5281 gttgctttcc gttgaaagtg cgccgaaaaa taaaaaagcc ttttacagta gcggtgtaca
     5341 agttggctac ggtgtaggtt tactgctttc aaccggactg gtttcattga tcagtatgat
     5401 gacgactgac gaacagtttt taagctgggg ctggcgcatt cctttcctgt ttagcatcgt
     5461 actggtactg ggagcattgt gggtgcgcaa tggcatggag gagtccgcgg aatttgaaca
     5521 acagcaacat aatcaagcgg ccgcgaaaaa acgcatcccg gttatcgaag ctctgttacg
     5581 acatcccggt gctttcctga agattattgc actacgactg tgcgagttgc tgacgatgta
     5641 cattgttact gcctttgcac ttaattattc aacccagaat atggggttac cgcgcgaact
     5701 tttccttaat attggtttgc tggtaggtgg attaagctgc ctgacaattc cctgttttgc
     5761 ctggcttgcc gatcgttttg gtcggcgcag ggtttatatt acaggcgcgt tgatcggaac
     5821 gttgagcgca tttcctttct ttatggcgct tgaagcacaa tctattttct ggatagtttt
     5881 cttctccata atgctggcaa acattgcgca tgacatggtg gtgtgtgtgc aacaaccgat
     5941 gtttaccgaa atgtttggtg ccagttatcg ctacagtggt gctggagtcg gttatcaggt
     6001 tgccagtgtg gttggcggtg gatttacacc ttttattgcc gctgcactca tcacttactt
     6061 tgccgggaac tggcatagcg tcgccattta tttgctggct ggatgcctga tttctgcaat
     6121 gaccgcttta ttgatgaaag acaatcaacg ctcgtgatag cctggcgaag atcatccgat
     6181 cttcgcctta tacttttgtt tcacattcct gtgacatact atcggatgtg cggtaattgt
     6241 atggaacagg agacacacat gaataataag ggctccggtc tgaccccagc tcaggcactg
     6301 gataaactcg acgcgctgta tgagcaatct gtagttgctt tacgcaacgc cattggcaaa
     6361 tatattacaa gtggcgaatt acctgatgaa aacgcccgca aacaaggtct ttttgtctat
     6421 ccatcactga ccgtaacctg ggacggtagc acaactaatc cccccaaaac gcgcgcattt
     6481 ggtcgtttta cccacgcagg cagctacacc accacgatta ctcgccctac tctctttcgt
     6541 tcgtatctca atgaacaact tacgttgctg tatcaggatt atggtgcgca tatctcggtg
     6601 caaccctcgc agcatgaaat cccttatcct tatgtcatcg atggctctga attgacactt
     6661 gatcgctcaa tgagcgctgg gttaactcgc tacttcccga caacagaact ggcgcaaatt
     6721 ggcgatgaaa ctgcagacgg catttatcat ccaacggaat tctccccgct atcgcatttt
     6781 gatgctcgcc gggttgattt ttccctcgca cggttgcgcc attataccgg tacgccagta
     6841 gaacattttc aaccgttcgt cttgtttacc aactacacac gttatgtgga tgaattcgtt
     6901 cgttggggat gcagccagat cctcgatcct gatagtccct acattgccct ttcttgtgct
     6961 ggcgggaact ggatcactgc cgaaaccgaa gcgccagaag aagccatttc cgaccttgca
     7021 tggaaaaaac accagatgcc agcatggcat ttaattaccg ctgatggtca gggtattact
     7081 ctggtgaata ttggcgtggg accgtccaat gctaaaacca tctgcgatca tctggcagtg
     7141 ctacgcccgg atgtctggtt gatgattggt cactgtggcg gattacgtga aagccaggcc
     7201 attggagatt atgtccttgc acacgcttat ttacgcgatg accacgttct tgatgcggtt
     7261 ctgccgcccg atattcctat tccgagcatt gctgaagtgc aacgtgcgct ttatgacgct
     7321 accaagttag tcagcggcag gcctggtgaa gaagtcaaac agcggttacg tactggcacg
     7381 gtggtaacca cagatgacag gaactgggag ttacgttact cagcttctgc acttcgtttt
     7441 aacttaagcc gggccgtagc aattgatatg gaaagtgcaa ccattgccgc gcaaggatat
     7501 cgtttccgcg tgccatacgg gacactactg tgtgtttcag ataaaccgtt acatggtgag
     7561 attaagcttc ccggccaggc taaccgtttt tatgaaggcg ctatttccga acacctgcaa
     7621 attggcattc gggcgatcga tttgctgcgc gcagaaggcg accgactgca ttcacgtaaa
     7681 ttacgaacct ttaatgagcc gccgttccga taataagtta tgaaccttct tatcagaaat
     7741 agatgtgaag gattaagtaa gacatctggc aaatagcctg caataaacgc gggctgtttg
     7801 cttccttggg cagatgcgag ttttattatc gtcttaatga tttccacata ttaaaagcaa
     7861 gtatgctttc aaaacaca
//
LOCUS       DAFGPF010000178         7768 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFGPF010000178 DAFGPF010000000
VERSION     DAFGPF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7768
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.178"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..489)
                     /locus_tag="LSX49_004807"
     CDS             complement(<1..489)
                     /locus_tag="LSX49_004807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171085.1"
                     /translation="MNKNESISYTEMQKFFAREIKEVGGRPITSKNLELSLLPIHARE
                     NLSAPEMPWYTEVNDIYMEFRRSPFWMVAGYVFLGFMLSLLSISILSIVAFSFYEMGF
                     NSDLLFLYLLAFVLGCFILPGAAKIAFFTPHYLPIRFNRKTQKIYVSDLIIEGNIFFG
                     KIK"
     gene            779..1021
                     /locus_tag="LSX49_004808"
     CDS             779..1021
                     /locus_tag="LSX49_004808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171086.1"
                     /translation="MNPLAGMDMSRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVD
                     QYLVNQSQTARTSVPGIWQGCEEDGVEYLRKLREKW"
     gene            complement(1203..2132)
                     /gene="fdhE"
                     /locus_tag="LSX49_004809"
     CDS             complement(1203..2132)
                     /gene="fdhE"
                     /locus_tag="LSX49_004809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HBL7171087.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AEHNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTTRIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(2129..2764)
                     /gene="fdoI"
                     /locus_tag="LSX49_004810"
     CDS             complement(2129..2764)
                     /gene="fdoI"
                     /locus_tag="LSX49_004810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HBL7171088.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            complement(2761..3663)
                     /gene="fdoH"
                     /locus_tag="LSX49_004811"
     CDS             complement(2761..3663)
                     /gene="fdoH"
                     /locus_tag="LSX49_004811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase O subunit beta"
                     /protein_id="HBL7171089.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFNVPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            complement(3676..6726)
                     /gene="fdnG"
                     /locus_tag="LSX49_004812"
     CDS             complement(3676..6726)
                     /gene="fdnG"
                     /locus_tag="LSX49_004812"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(6139..6141),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HBL7171090.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSTWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSIGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGANPDQVLNMTWNY
                     AIPHEPKSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            6920..7753
                     /gene="fdhD"
                     /locus_tag="LSX49_004813"
     CDS             6920..7753
                     /gene="fdhD"
                     /locus_tag="LSX49_004813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBL7171091.1"
                     /translation="MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
BASE COUNT         1797 a         2015 c         2028 g         1928 t
ORIGIN      
        1 ttttattttt ccaaagaaga tattgccttc aataattaaa tctgaaacat aaattttttg
       61 tgtttttctg ttaaatctta taggaagata atgtggcgtg aaaaaagcaa tttttgcagc
      121 gccaggtaat ataaaacagc caagcacaaa tgcaagtaga tacagaaata acaagtcact
      181 attaaagccc atctcataaa atgagaatgc aacaatagat aatatcgaga tggaaagtag
      241 tgaaagcata aatcccagga atacataacc ggcaaccatc cagaatggtg agcgtctgaa
      301 ctccatatag atatcattaa cttcggtata ccacggcatt tctggcgcag aaaggttttc
      361 cctggcgtga atgggtagca gacttaactc taaattctta gaagtgatgg gcctaccgcc
      421 tacttcctta atttctctgg caaaaaattt ttgcatttcg gtgtaagaaa ttgattcgtt
      481 tttattcatt atatctgttc cgttccctga cgacttatcg ttttttcttg gtagatgaca
      541 ttaagctatt ggatgtgaga aaggcaactt tatagagtaa attcagaaag agtagaaatt
      601 ttcacacgac tgttttcact tccatttttt actggttttc gtaataactg caactgttac
      661 atcgtatctg gaaaacgcct cgcaaaaata aaaagtgatg cgtaaatgcg ctttctttaa
      721 agattcgaca agggtacttt tctctccata gattcaaaat gatattggcg agatatttat
      781 gaaccctctg gcaggtatgg atatgagcag aattttactc gatttatcga atgaggtgat
      841 taagcaactt gatgatcttg aggtgcagcg taatcttccg cgtgcagacc tattacggga
      901 agcggtagat caatacctgg taaatcaatc gcaaacagca agaaccagtg ttcctggcat
      961 ctggcaaggg tgtgaggaag atggtgtcga atacctgcgt aagctgcgcg agaaatggta
     1021 atggcaaaaa gatttggcta tttgatatcg atatccttat cgattttctc agcgtgaaaa
     1081 ttgaggccaa acaggcactg gcggcatagc ttgaggaggt aacgcggaat acgagagata
     1141 gtgtcgtcac accctatgaa ctgtaatccg ggcgacctgc gccacccgga aaacgtcaga
     1201 gattactccc cttcacccgg aaacaggaac gggttgatgg aactacgggc atagccttct
     1261 tgctccattc gcgcgtccag taccagagag gcgaggtcat ctgccacggc ttcaactttc
     1321 ggttcttttt cctgataaag aatcttcagg taagtgccgc agtcatcgca gctttcggct
     1381 ttaatcgcgg cctgttcgtc atccagcgac cagtaatgca gtttgccgct ctgttcacag
     1441 ttgctgcatt ttacgcgcac tacgtgccat tcagtttcac acaggttgca gtgcaggtaa
     1501 cgcagaccct gagtggtgcc aatttgcacc atgctggaca ccggcataga gccacatacc
     1561 gggcaatatt gacgttgttc gccgtattca gcgcgggctt tgccggggat cagattagcc
     1621 atctgcgccc agtagagcga cagcgcagcc cagataaacg gcgctttatc gctgctgacg
     1681 gacgagaaat cagaggcaaa cagtgcgctg gccatatctt ccagctcctg agtcgatgcc
     1741 ttctccagat tctcaatcac tgccagcgcc gggccgctca tttcaggttt cagctcagca
     1801 atcagcgcca tcagcagctt ttgccagtgc ttatcacgcg gcagaacgtg aatatccagc
     1861 gggggcttgc cttgtgcgct ggcttcttta atgcgcgtgg tcagatccat ctccagcgga
     1921 tggtcgtaca gcaccacttc ctgggcgtgg gcgataagcg cagcaaagcg caggtaatca
     1981 cccagcggat tatgttctgc cagctcgcgc agacgctcgg cgcggcggtt gtataaattc
     2041 ttgagccgag ggaacaataa cggcggaatc atatccgccg tacgtttctc gctcgaaccc
     2101 agctcatctt gcgggattat gcgaatactc attcagcttt cttttccgtt gtcttgcgga
     2161 cctcacggta ccagcgcggg tgatgtttct ttgcccatgc gctggtcacc catccttcca
     2221 ccatggcggt aatcgtgcct ttcacccaaa gggcggcgta gatatgcacc atgataacca
     2281 caattaacgc cactgcggca aatgaatgca gcattaacgc gaatcggatc accgggattg
     2341 agaaagcagg cgcaaaataa ggacgccaga taatcacgcc gctcaccagc aacaggacca
     2401 ggaaaataat cgccgcccag aaaacgcatt tctgaccgaa gttataacgc ccggtgtcac
     2461 ctacttcctc gttgacgacg atcttacgaa tattcttcgc ccaaaagata tcatcccgat
     2521 tgattaggtt gtgatgccag taacggaaaa acatgatgat gaacgaggca aacataacca
     2581 cgccgacaaa cggatgcaga attcgcgcca gctgcggtgt gcccatgatt tgcatcaacc
     2641 agttgaagga cgggaacaaa aagcccagcc cgctcaccgc cgccaggatg aagcagaagg
     2701 cggtgatcca gtggttgata cgttccggcg cggtgtagcg cacgatggtg tcacgtcgtt
     2761 tcatttgcgc tcctcgtctt tctcttcgtg cagattattc tcttcctcat ccgcacggtt
     2821 cggaccgaca cccacgtagt ggaagatact ggctgcgaag gtagccgcaa agccaacagc
     2881 tgcgagtggt ttccagatgc ctttccagaa tttcacggtt tcgctgattt ccgggttctc
     2941 cggcaagcca tgatacagat ttggcttgtc agcatggtgc agtacgtaca taacgtgtgt
     3001 accaccgacg cctgccggat cgtacagacc cgcattgtcg taaccgcggg ttttcagctc
     3061 cgccacgcgc tcgctcgcca gcgttttcat cgactctttc gtaccgaagt gaatcgcgcc
     3121 cgttgggcag gtcttcacgc aggccggttc ttgcccaacc accacgcggt caacgcacaa
     3181 cgtacatttg tagacgcggt tgtcttccgg gttgaggcgt ggcacgttga acgggcaccc
     3241 tgcgatgcaa taaccgcagc cgatgcactg ctcggactgg aagtcgacga taccattggc
     3301 atactgaata attgcccctt ccgccgggca tgctttcagg cagcctggat cggaacagtg
     3361 catacagccg tctttgcgga tcagccattc cagtttgtcg ttctgctcca cttccgagaa
     3421 tcgcatcacc gtccacgatt tggcacttaa atcattgggg ttgtcataca ccccaatgtt
     3481 attgccgacg gtatcgcgaa tgtcgttcca ctctgaacac gccacctgac aggctttaca
     3541 gccgatacag gtggtaacgt cgatgagttt cgccacttct tcctggaagt cccgcgcctg
     3601 aggcgcgggg gtcagaccgt tagtcgcgga acgacgaatg atatcttgcg attgataagc
     3661 catatgtcgt ctccgttaca ccttttccac attcacaagg aaggacttaa actccggcgt
     3721 ctgcgtgttc gcatcaccga cgaatggcgt caacgtattg gcaataaagc cttttttcgc
     3781 aacaccttca tagccccagt gaatcggaat accgatggta tcgatatctt tgccgtttgc
     3841 tttcagcgtg cgaatacgtt tggtcactac cgctttggct ttgatatagc cacggttgga
     3901 ggagactttc acagtatcgc cctgggcaat gccaagttta ttcgccagcg actccccgat
     3961 ttccacaaac tgctctggtt gcaaaatcgc gttcaacagc gcgtgtttgg tccagtagtg
     4021 gaagtgctcg gtcagacgat aggtggttcc gacatacggg aacttatcgg ctttccccaa
     4081 tgcttcggca tcgtctttaa agatacgcgc cgccggattc gagataacgt ttggatgcag
     4141 cgggttagtt cccagcggcg tttcaaacgg ctcgtagtgt tccgggaacg gaccttccgc
     4201 catcttatcg agggcaaaca gacgccccat gccttcctgc tgcatgataa acggcccgac
     4261 gccactgccc ggaggcgctg cgctgtagtc cggaatatcc cagccggtcc acttagtgcc
     4321 gtcccatttc agcaactgac gcttcggatc ccacgggtta ccctgcggat ctgcggaggc
     4381 gcggttatac agaatgcggc ggttaagcgg ccatgcccat gcccagccca gcgtgttacc
     4441 gaggccagac ggatcggcgt tatcacgacg cgccatctgg ttgccttctg gcgtccagct
     4501 accggcgaaa atccagcagc cacaggaggt tgtaccgtca tcgcgcagtt gagcgaacga
     4561 gctaagttgt tggcctttct tgacaataac cgcaccggtt gccggatcgg taatatcggc
     4621 cagcgcctta ccgttgctct ccatcgccac ttcttccgac ttcggctcat gcgggatggc
     4681 gtagttccag gtcatgttca gcacctggtc cgggttcgcg ccaccctgtt cggcatacat
     4741 cttgcgcaag cgcaggaaga taccggagag gatctcgcca tcagtcagcg caatccccgg
     4801 ggcgtccgca cctttccagt gccactgcaa ccagcgacca gagttaacga ttgaaccgtt
     4861 ctcttccgcg aagcaggtcg atggcagacg gaacacttcg gtctggatct tcgacgagtc
     4921 aacttcgttc agttcaccgt ggttctgcca gaagttagag gtttcagtgt tcagcgggtc
     4981 gatagtcacg aggaatttca gcttcgacag acagccgatc actttgtttt tgttcgggaa
     5041 tgaggcaaca gggttaaagc cctggcagat atagccattg accttgccct ctttcatcat
     5101 ctcgaagtat tgcaggacgt cgtagccttt atcccacttc ggcaaccagt caaagcccca
     5161 gctattttcc gccgtcgctt tatcaccaaa gaaggccttc atcatagaga cgaagaattt
     5221 cgggtagttg ccccagtagt taacctggcc ttccagcagt ggtttcggcg tgttggcggt
     5281 aaggtaagtt tgcagatcgg tctgcttctc gcttggcagc gtcatgtaac ctggcagact
     5341 ctgcgacagc agccccaggt ccgtcagccc ctgaatattg gagtgaccgc gcagggcgtt
     5401 aacgccgccg ccagccatcc ccatattgcc gagcagcaac tggatcatcg ccatcgtacg
     5461 gatgttctgc gcaccgatgg agtgttgcgt ccagccgagg gcgtaaagga acgaggcagt
     5521 tttatcgtga gcactggtct ctgcgatgta ttcgcagact ttcaggaatg cgtcttttgg
     5581 cgtaccgcag atgttttcaa ccacatctgg cgtgtagcgg gaaacgtgct gtttcagcaa
     5641 gttccacacg caacgtggat gttgcagggt agtatcgcgt ttggcgaagc cgttttcgtc
     5701 cagttcgtaa gtccaggtgg acttatcgta cttgcgtttt tccgcgtcgt agccggtgaa
     5761 caggccatct tcaaagccgt aatcctcacg cacgatcagg ctagcgttgg tataggcttc
     5821 ggtgtattcg cggttgaatt tttcattgtt cagcaggtac agcaatacgc ctgacaggaa
     5881 agcaatgtca gtaccggaac ggataggggc atagtagtca gccaccgccg ctgtacgcgt
     5941 aaagcgagga tcgatcacaa tcagcttcgc gccgttgtga attttggctt ccatcgccca
     6001 gcggaacccg accgggtgag cttcagcggc gttaccgccc atcaccacga cgaggttggc
     6061 attcttgatg tcgacccagt ggttggtcat cgcaccgcga ccaaatgttg gagcaagact
     6121 tgctaccgtt ggtccgtgtc agacacgcgc ctggttgtcg accgcgagca tacccagcgc
     6181 gcgggagaat ttttgcgtta aatagccggt ttcgttgctc gacgcggaag cacacagcat
     6241 cccggtggag agccagcggt taacagtcac gccttcggcg ttttgcgcaa tgtagtttgc
     6301 atcgcggtct tctttcatca gtttggcgat gcgatcaaac gcctcttccc aactgatttg
     6361 ctgccattta tcagaacctg gcgcacggta ttccggaaac ttcagacggc tttcggagtg
     6421 gatgaaatcc accaggccag cgcctttcgg acaaagtgct ccgcggttga ccgggtgatc
     6481 cgggtcacct tcgatatgga agatagatgc tttggcgttt tttgctccgt caccgaggct
     6541 gtacatcaac agcccacagc ctacggaaca ataggtgcag gtattacggg tttcgcgggt
     6601 gcgcagcagt ttatactgcc gggtttccgc gagtgctacg ctgggtgcaa aacccagtgc
     6661 cgctgccgtg gtgcctgcca taccgccagc gcagatctta aagaactgcc ttctgctgac
     6721 ctgcatggat tgctccttgt ttcgacattg tcacgtccca tttacattcg cttgctgcgt
     6781 gtgcagggag tgggagttat ttttctttgc ggaaggggcc gcaaaggtcc agaattggct
     6841 caatttccct ccatccagga agggtttgta acagaatacc ataatgttgg tgtgtgtgtt
     6901 cttatctggt taatagaaag tgaaaaaaac acagcaaaaa gaaatcgaga atgtgacaaa
     6961 tatcacaggt gttcgtcaaa ttgagttatg gcggcgtgat gatttacaac acccacggtt
     7021 agatgaggtg gcggaagaag ttcccgttgc gctggtctac aacggcattt cgcacgtggt
     7081 gatgatggcg tcgcccaaag accttgagta ctttgcgctc ggtttttcgc tttccgaagg
     7141 aattatcgaa agcccgcgcg atatcttcgg catggatgtc gttccttcct gtaatggcct
     7201 ggaagtacaa attgagcttt ccagccgccg ctttatgggg ttgaaggaac gtcgccgggc
     7261 gctggcggga cgtacgggct gtggcgtatg cggtgtagaa cagcttaacg atatcggtaa
     7321 accggtgcag ccgctgccgt tcacccagac gtttgatctc aacaaactgg atgatgcatt
     7381 acgtcatctc aatgatttcc agccagtggg gcaactgact ggttgtactc acgccgctgc
     7441 atggatgttg ccatctggcg aactggtcgg cgggcatgaa gacgtgggtc gccatgtggc
     7501 gctggacaaa ctgttaggcc gccgatcaca agaaggggaa agctggcagc aaggtgcggt
     7561 gctggtttcc agccgtgcca gttatgaaat ggtgcaaaag tcggcgatgt gcggcgtaga
     7621 gattttgttt gcggtgtctg ccgcgaccac acttgctgta gaagtggctg agcgctgtaa
     7681 tctgacgctg gtgggctttt gtaaaccggg tcgggcgacg gtttataccc atccgcagcg
     7741 tttgagcaat taattaaaat aagtcctg
//
LOCUS       DAFGPF010000179         7741 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFGPF010000179 DAFGPF010000000
VERSION     DAFGPF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7741
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.179"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(54..932)
                     /gene="glxR"
                     /locus_tag="LSX49_004814"
     CDS             complement(54..932)
                     /gene="glxR"
                     /locus_tag="LSX49_004814"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBL7171092.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTDASDIIFIMVPDTPQVEDVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     gene            complement(1032..1808)
                     /gene="hyi"
                     /locus_tag="LSX49_004815"
     CDS             complement(1032..1808)
                     /gene="hyi"
                     /locus_tag="LSX49_004815"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HBL7171093.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKQVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPTGFSSEQIHTTLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYEYLFTVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     gene            complement(1821..3602)
                     /gene="gcl"
                     /locus_tag="LSX49_004816"
     CDS             complement(1821..3602)
                     /gene="gcl"
                     /locus_tag="LSX49_004816"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HBL7171094.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAVLLQQFAELTSIPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPERNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKILMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAADAPTETCFMHYE"
     gene            complement(3692..4507)
                     /gene="allR"
                     /locus_tag="LSX49_004817"
     CDS             complement(3692..4507)
                     /gene="allR"
                     /locus_tag="LSX49_004817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HBL7171095.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDNQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHL"
     gene            complement(4585..5067)
                     /gene="allA"
                     /locus_tag="LSX49_004818"
     CDS             complement(4585..5067)
                     /gene="allA"
                     /locus_tag="LSX49_004818"
                     /EC_number="4.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HBL7171096.1"
                     /translation="MKLQVLPLSQKAFSAYGDVIETQKRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     gene            5297..6223
                     /gene="allS"
                     /locus_tag="LSX49_004819"
     CDS             5297..6223
                     /gene="allS"
                     /locus_tag="LSX49_004819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HBL7171097.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLCQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVARLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMLDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            6292..7398
                     /gene="mnmH"
                     /locus_tag="LSX49_004820"
     CDS             6292..7398
                     /gene="mnmH"
                     /locus_tag="LSX49_004820"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBL7171098.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMN
                     NDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQ
                     RSHIVQSWLHDAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENMLAAEMLKTDAHQDLRLWVLEDES
                     RMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKTYACGY"
     gene            complement(7450..>7741)
                     /locus_tag="LSX49_004821"
     CDS             complement(7450..>7741)
                     /locus_tag="LSX49_004821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2931 family protein"
                     /protein_id="HBL7171099.1"
                     /translation="VWKLMLTPYSPPGGGSEKYYLRYLLIGLAPEGKIGVWLEKPDKP
                     NIRLTDKQILIETVSGEKMEMCNGRSAYKHGYSYPESTKNFIKDKKYPYGNW"
BASE COUNT         1958 a         2042 c         1841 g         1900 t
ORIGIN      
        1 ttaatattgc tggccgattc attttctgat atcggccatt tttattgcgg gtatcaggcc
       61 agtttatggt tagccattaa ttccagcgcc tgcactaatg cagagtgatc caactggctg
      121 ccaccgtttg ccgcacaggt attaaacaat tcctggcagg tcgcggtgtt tggcaggttc
      181 agcgccagtg ctttcgcact ttgcagtgcc aggttgagat ctttctggtg cagcgcaatt
      241 ttgaaacctg gattaaaggt gcgtttaatc atgcgctcac cgtgaacttc cagaatacgt
      301 gaggaagcaa agccgcccat cagcgcctgg cgcacacgta ccgggtccgc accggctttt
      361 gaagcaaaca acaaggcttc agaaaccgct tcaatattga gcgccacgat aatctgattt
      421 gccactttgc aggtttgacc gtcgccgtta ccgcccacga gagtgatatt tttaccgagc
      481 agttcaaaca gcggttttac acgttcaaat actgcttcat caccgccaac cataatcgat
      541 aacgtccctt cacgcgcgcc gatttcaccg ccggagactg gcgcatcgag ataatcgccg
      601 cccagttcat tcacctgacg agcgaaacgt ttagtttcaa tcggggaaat ggagctcata
      661 tcaacaatgg ttttgccctt cagcgaggct ttggtacaac cattttcacc aaacagaacg
      721 tcttcaacct gtggcgtatc cggcaccata ataaaaatga tgtccgatgc atctgttacc
      781 tggcgcgcag tttcaacact aacggcgccc agtgacagta attcatcagc aaccggacca
      841 atggttgtga catgcagttg atgaccggca cgcgccagat taatggccat cggtgtaccc
      901 ataatgccta agccaataaa tcccagtttc ataattaacc tcttttaaat ttcgcttttc
      961 ctgaattcag acaacacgat cccctgccaa cttagcggcc taaaaaagca ttgtctgaat
     1021 agcgttacgt tttaacggta cgggtccatc cagcgtaaac cggcttccgt ggtggtttgg
     1081 ggtttatatt cacagccaac ccaaccgttg tagtcagaat tttcaattac cgtaaagaga
     1141 tattcgtaat taatttctcc ggttcccggt tcgccgcgat gcggattatc agcaatttgc
     1201 aggtgaccaa ttttatcggc ccactgagtc atggtattgg ttaattcacc ttccatccgc
     1261 tgcatgtgat aaatgtcata ctgaattttc aaattgcagc aaccaacatc gtcaatcagt
     1321 ttcagtgcct gccgggttcc ggtgagatga aaaccaggaa tatcaaaatg gttaataggt
     1381 tcaatcagta ataaaatatc ttctttcatc agcatattcg cagcataacg caggttttct
     1441 acaagcgttg tgtgaatctg ttcactgctg aaaccagtcg gtgttttacc gaccagacag
     1501 ttaatttttt tattacccag cgcacgagca taacgaatcg ctgctgctac gccatcccga
     1561 aactcttctt cacggccagg aatacaggca ataccccgct cgcccgccgc ccagtcacct
     1621 gccggtaaat tgtgcagcgt atgttcaagt ttattactcg ccagcacctg ttttaattct
     1681 tcaatgtcgt agtcataagg gaacataaat tcaacgccgc gaaaaccaca ctgcgcagct
     1741 ttctcaaaac gggcgagaaa atcatattca ccaaataaca tcgataaatt agcagagaaa
     1801 cgtaacatta tttatctccc ttattcatag tgcatgaaac aggtttcagt cggtgcatcc
     1861 gctgcgttat cggcgatatc ttcaaattcc atgacgttat ccagttcact gcccatcgaa
     1921 atattagtca cacgctcgag aataacttcc acgactaccg gtacccgata ttgcgccatt
     1981 aagattttcg cctgttcaaa ggctggtgca atatcttccg gtttgaaaac gcgaattgct
     2041 ttacaaccta aaccttccgc tacttttacg tggtcgacgc cataaccgtt cacttcgctg
     2101 gagttaatat tttcgaacgc gagctgtacg cagtaatcca tatcaaaggc acgttgcgac
     2161 tggcgaatca gacccagata ggcgttattg accagtacat ggatgtacgg aatgttgaac
     2221 tgtgcgccaa cggctaattc ttcaatcagg aactggaagt cgaagtcacc ggaaatcgcc
     2281 accacattgc gctctggatc agcggcacaa acccccagcg ccgccggaat cgtccagccc
     2341 agcgggcctg cctgcccaca gttgatccag tggcggtctt taaagacatg cagcatttgt
     2401 gccgcagcga tttgtgacag gccaatggtg gtgacataac aaacatcgcg gccaaaggct
     2461 ttgttcatct cttcatacac gcgctgcggt ttcaccggca cgttgtcgaa gtgggttttg
     2521 cgcagcaaag tgcgtttgcg ctgctggcag tcggcgaccc actctttacg acacggcaga
     2581 cgaccggctt tttgcatctc ctgcgccact tcaaccagca gcgtcagcgc cgctttagca
     2641 tcagagacaa tgccaagatc cggacacagc acgcggccaa tttgcgtcgg ctcaatatcg
     2701 atatgaacga ttttgcgccc ttcggtgtat ttctctaccg aaccggtatg acggttagca
     2761 aaacggttac cgataccaaa caccatgtcg gacgccagca acgttgcatt accgtaacga
     2821 tgcgcggttt gcaggcccac catcccggcc atcagttcat gatcgtccgg gatacagccc
     2881 cagcccatca gcgttgggat caccggaatg ctggtcagtt cagcaaactg ttgtaacagt
     2941 acagctgcgt cagcattaat taccccgcct ccggcaacaa tcaccggacg ttcggcctgg
     3001 attaacattt ctacagcttt ttcgatctgc atacggctgg cagcaggttt gtagaccggc
     3061 agcggttcgt acatatcagg atcaaactcg atttccgcaa cctgtacgtc gaacggtaaa
     3121 tccaccagta ccggacccgg tcgaccagaa cgcatcaggt gaaacgcctg ttgcagcaca
     3181 cgaggcacca gcgccgcttc acgaactgta accgccattt tgctgaccgg tttagcaatt
     3241 gcttcaatat caacggcctg gaaatcttct ttatgcagac gggcgcgcgg agcctggccg
     3301 gtaatacaca gaataggaat ggaatcagca gatgcggaat agagcgcggt gatcatgtcc
     3361 gtgcccgcag gaccggaagt ccccagacat acgccgatat tccctgccgt tgcgcgggta
     3421 taaccttccg ccatgtgcga agcaccttcc acatgacgcg ccagaatgtg acgaataccg
     3481 ccgtgcttac gcatcgctga gtagaacgga ttgattgcag ctcccggaac gccgaaggcg
     3541 gtggtgatac cttctttctc cagcacatac attgccgcgt caacggctct catttttgcc
     3601 attttattcc tacctctatt aattggaaaa attttccaac tttcaaattt tgtcaaaaaa
     3661 acccgctccg cagagcggga tacgacagac actatagatg tgctttcagt cccaacgccg
     3721 tgctgatatc gcgggcggtg tctctgacca gctcaccctg actgacaaaa cgatcttctg
     3781 tcagtcttga tgaaggcccg gagatggaga tagcggcaac aacactacct acatcatcgt
     3841 aaattgctga agctatgcaa ttcaggccga caacatgctc ttctttatct acggtatagc
     3901 ccagttcacg cgcttgttcc aggtccttca gcaaggtggg catatccaca agtgtcgttg
     3961 gcgtaaactg ctgcaaaccg gtttgcagaa tgatgctcat caactcttct tccgccagcg
     4021 gataaagcag cgccttgccc gctccggaag catgcagcgg cagacgactg cccagcggcg
     4081 cacacatcct gaccatcgat ttacactcta actgaccaat taataccgct tcattgccgt
     4141 tacggatcgc gacattgacc gtttcgccgg aaagtaacat caggcggcgc ataaacggcc
     4201 cggcgacgga gaggacatcg cggttatgga tgtacgctgc accgacgtta aagacaccta
     4261 atcctatatg ccaccagcct aactgattgt cctgatagac aaaatccgct gcctgtaaaa
     4321 ccttcagcaa gcgaaaggtc gtggagagcg gcaaatccag attgagagag atatcgctaa
     4381 ccgacgaact tcccccactt ttttccagat attgcagaat cgcaattccc cgctctaacg
     4441 cctgtgcgcc cttctgtgct acaggctccg cctgtcctgg cctgccgcgc cgtctaactt
     4501 ccgtcatacc tacgttaact ccgacctaca aatgagcata aacaatgaac aattcgttta
     4561 tcttatgcaa gtcggttgca ggcgtcacgc aaaacagagt tcctgttcag gaatactttc
     4621 aacatcacag ttgtcactgc cgccgcgatc gatggtcaga aaatcggtga cgcgctgcca
     4681 ggcgaaaagt gggtgatgcc agacgttacg atggtaattc actccctgtt cgccattggt
     4741 aataaacgcc cgcagggttg acaggtctgg tttgtcgtca cctaacgcca ccaccaccac
     4801 aaacacttca cctttcatcg ggataaacgc ctgtgtaccc agcggatgac gttcgagttc
     4861 gtgaatggtc agcggcagat tcgccggttg cgcgcggtta atgctgataa gcgtacggtc
     4921 ttgctcaaga atctcaacca gcgccaaatc gtggtaacgc tccaccagtc cattgttaat
     4981 atggaaaaaa tcccgtttct gcgtttcgat tacgtcgcca taagcactaa aggctttctg
     5041 acttaacggt aatacctgaa gtttcatctt tttgtccttg taacataatt ccgttcaacc
     5101 accgccgacc ggtcagcttg gtttcaataa caggcaatct aaaaccttaa gagaacaaca
     5161 tcaacacaaa agttggaata tttttccaaa actagattta gtccacaaat tgaacagggt
     5221 tatcatgtaa aaatactgat aaatcagagg ataagaaaat cacgcaactt gcggatttaa
     5281 aaggggatac ctgaagatgt tcgatccaga aaccttgcgg actttcattg cggttgctga
     5341 aacaggtagt ttttcaaaag cggcagaacg attatgtaaa accacggcga cgatcagtta
     5401 tcgcattaaa cttctggaag agaataccgg agtggcgctg tttttccgca cgactcgcag
     5461 cgtgacgttg acggcggctg gcgagcatct actttgtcag gccagagact ggctgagctg
     5521 gctggaaagt atgcccagcg agttacaaca ggtgaatgat ggcgtggaac gccaggtgaa
     5581 tatcgtcatc aacaacctgc tctataaccc ccaggccgtt gccaggctgc tggcgtggct
     5641 aaatgaacgt tacccgttta cccaatttca catctcccga caaatctata tgggcgtctg
     5701 ggactcgcta ttgtacgaag gtttttcact ggctatcggc gtcacgggaa ccgaggcgct
     5761 ggcaaatacc tttagtcttg atcccttagg atcggtgcaa tggcgctttg tcatggcggc
     5821 ggatcatccg ctggcgaacg ttgaagagcc gctaacagaa gcacagttgc ggcgctttcc
     5881 ggcggtcaat attgaagaca gcgcccgcac cttaaccaaa cgcgtcgcct ggcgattgcc
     5941 ggggcaaaaa gagattattg ttcccgatat ggaaacgaaa atcgccgccc atctggcggg
     6001 cgttggcatt ggttttttgc caaaatcact ttgccagtca atgctcgata atcaacaact
     6061 ggtcagccgg gtaatcccaa cgatgcgccc tccttcgcca ttgagtctgg catggcgcaa
     6121 atttggcagc ggcaaagcgg tagaagatat tgtgaccttg tttacccagc gcaggccgga
     6181 aatcagcgga tttttagaaa ttttcggcaa cccacgcagt taaaaatcaa gtttccttgc
     6241 gcgttggcgc gtaaaatagc gcgcaagctg atttgaggtt cactttttac tatgcaagag
     6301 agacacacgg aacaggacta tcgtgccctg ctgattgctg atacgcccat tattgatgtt
     6361 cgcgccccca tcgagtttga gcaaggcgca atgcccgccg ctatcaacct gccgttaatg
     6421 aataacgatg aacgcgccgc cgttggcatc tgctataaac agcaagggtc agacgcggcg
     6481 ctggcactgg ggcataaact ggtggcgggt gaaattcgtc agcagcgcat ggacgcctgg
     6541 cgggcagcgt gcctgcaaaa tccgcacggt attctctgct gcgcccgtgg cggtcagcgc
     6601 tcacatattg tgcaaagctg gttgcatgac gcggggattg attatccgct ggtggaaggc
     6661 ggttataagg cactgcgcca gaccgcgatt caggcgacta ttgaactggc acaaaaaccg
     6721 atagtgctga ttggcggttg taccggcagc ggtaaaacgc tgttagtgca gcaacagccg
     6781 aacggtgttg atctggaagg gttggcgcgt catcgcggtt cggcgtttgg tcgcacctta
     6841 caaccacaac ttagccaggc gagttttgaa aacatgctgg ctgccgaaat gctaaaaacc
     6901 gacgcccatc aggatttgcg cctgtgggtg ctggaagatg aaagccggat gatcggttcg
     6961 aatcacctgc cggaatgtct gcgcgaacga atgactcagg cgacgattgc ggtggtagaa
     7021 gatccgtttg agatccgtct tgaacgcctg aacgaagaat atttcttgcg tatgcatcat
     7081 gattttaccc acgcttatgg cgacgaacag ggctggcagg agtattgcga atacctgcat
     7141 cacgggcttt cggcgattaa acgtcggctg ggactacaac gctataacga actggctgca
     7201 aggctggatg cggcgctgac aacgcaactc accaccggca gcaccgacgg tcatctggcc
     7261 tggctggtgc cgttacttga agaatattac gacccgatgt atcgctatca gcttgagaaa
     7321 aaagcggaaa aagttgtctt tcgcggtgag tgggcggaag tggcggaatg ggttaagact
     7381 tatgcctgtg gttattaacc cacaaaaatg cttttccgtt cctctttaat aaattgtgca
     7441 actggttaac taccagttgc catagggata ttttttatct ttgataaagt tttttgtact
     7501 ttccggataa gaatacccat gtttataggc acttcggccg ttacacattt ccattttttc
     7561 acctgaaacc gtttctatca gaatctgctt atccgtcagg cgaatattgg gcttgtcagg
     7621 tttctccagc cacactccta ttttcccttc cggagccagc ccgattaaca gataccgcag
     7681 ataatacttt tcactgccac cgccaggtgg tgaataaggt gtgagcatca atttccagac
     7741 g
//
LOCUS       DAFGPF010000180         7719 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFGPF010000180 DAFGPF010000000
VERSION     DAFGPF010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7719
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.180"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..985
                     /gene="ldhA"
                     /locus_tag="LSX49_004822"
     CDS             <1..985
                     /gene="ldhA"
                     /locus_tag="LSX49_004822"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HBL7171100.1"
                     /translation="LAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANGCE
                     AVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEA
                     VAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAMLRI
                     LKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEAAF
                     DQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVIQD
                     DVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            1096..1518
                     /gene="hslJ"
                     /locus_tag="LSX49_004823"
     CDS             1096..1518
                     /gene="hslJ"
                     /locus_tag="LSX49_004823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HBL7171101.1"
                     /translation="MKKVAALVALSLLMAGCVSSDKIAVTPEQLQHHRFVLESVNGKP
                     VTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(1515..1781)
                     /locus_tag="LSX49_004824"
     CDS             complement(1515..1781)
                     /locus_tag="LSX49_004824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HBL7171102.1"
                     /translation="MRAAFWVGCAALLLSACSREPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            2055..5579
                     /gene="nifJ"
                     /locus_tag="LSX49_004825"
     CDS             2055..5579
                     /gene="nifJ"
                     /locus_tag="LSX49_004825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBL7171103.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISHIATLKSR
                     VPFIHFFDGFRTSHEINKIVPLADDTILELMPQAEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEQAMNDFAAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTSEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRNVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARF
                     TVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSAAEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPTELLT
                     ALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSEALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
     gene            5945..7078
                     /gene="ompN"
                     /locus_tag="LSX49_004826"
     CDS             5945..7078
                     /gene="ompN"
                     /locus_tag="LSX49_004826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HBL7171104.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSTNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADVGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            7219..7653
                     /gene="uspF"
                     /locus_tag="LSX49_004827"
     CDS             7219..7653
                     /gene="uspF"
                     /locus_tag="LSX49_004827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HBL7171105.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEAEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEL
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
BASE COUNT         1979 a         1927 c         1927 g         1886 t
ORIGIN      
        1 actcgccgtt tatagcacaa aacagtacga caagaagtac ctgcaacagg tgaacgagtc
       61 ctttggcttt gagctggaat tttttgactt tctgctgacg gaaaaaaccg ctaaaactgc
      121 caatggctgc gaagcggtat gtattttcgt aaacgatgac ggcagccgcc cggtgctgga
      181 agagctgaaa aagcacggcg ttaaatatat cgccctgcgc tgtgccggtt tcaataacgt
      241 cgaccttgac gcggcaaaag aactggggct caaagtagtc cgtgttccag cctatgatcc
      301 agaggccgta gctgaacacg ccatcggtat gatgatgacg ctgaaccgcc gtattcaccg
      361 cgcgtatcag cgtacccgtg acgctaactt ctctctggaa ggtctgaccg gctttactat
      421 gtatggcaaa acggcaggcg tgatcggtac cggtaaaatc ggtgtggcga tgctgcgcat
      481 tctgaaaggt tttggtatgc gtctgctggc gttcgatccg tatccaagtg cggcggcgct
      541 ggaactcggt gtggagtatg tcgatctgcc aaccctgttc tctgaatcag acgttatctc
      601 tctgcactgc ccgctgacac cggaaaacta ccatctgttg aacgaagccg ccttcgatca
      661 gatgaaaaat ggcgtgatga tcgtcaatac cagtcgcggt gcattgattg attctcaggc
      721 ggcaattgaa gcgctgaaaa atcagaaaat tggttcgttg ggtatggacg tgtatgagaa
      781 cgaacgcgat ctgttctttg aagataaatc caacgacgtg atccaggatg acgtattccg
      841 tcgcttgtct gcctgccaca acgtgctgtt taccgggcac caggcattcc tgacagcaga
      901 agctctgacc agtatttctc agactacgct gcaaaactta agcaatctgg aaaaaggcga
      961 aacctgcccg aacgaactgg tttaatcttg ccgctcccct gcattccagg ggagcttatt
     1021 cagataatcc ccaaagacct ttcatcctct attcttaaaa tagtcctgaa tcagaaacag
     1081 taattgagaa ccacaatgaa gaaagtagcc gcgcttgttg cgctaagcct gctgatggcg
     1141 ggatgtgtaa gtagtgacaa aattgctgta acgccagaac agctacagca tcatcgcttt
     1201 gtgctggaaa gcgtaaacgg taagcccgtg accagcgata aaaatccgcc agaaatcagc
     1261 tttggtgaaa agatgatgat ttccggcagc atgtgtaacc gctttagcgg tgaaggcaaa
     1321 ctgtctaatg gtgaactgac cgccaaaggg ctggcaatga cccgtatgat gtgcgctaac
     1381 ccgcagctta atgaactcga taacaccatt agcgaaatgc tgaaagaagg tgcacaagtg
     1441 gatctgaccg cgaaccagtt aacgctggcg accgcgaaac agacattaac ttataagctg
     1501 gcggatttaa tgaattaata gctgccacag ctcccggcgg caagtgactg ttcgctacag
     1561 cgtttgccgt tgggtaatgc acacatccca atcgccgtac catccagttg acgggcaaca
     1621 gaaagcgaac cgccgatcat tgcacaattt gcttctccac tactggacat cgacgctttt
     1681 aaacctggcg ctacgtgcgc cgcagtcgcc tgctgaacag gttcacgact acacgccgac
     1741 aacaataaag cggcacaccc tacccaaaac gctgctcgca tcttttcttc ctctgatctt
     1801 caagccaaac gacaccgcca taaataatag gcagcacaga gggcggcgtc gagagctgtc
     1861 ctgcgcgttg ccccgcattt ttactttttt atggctattt ttttgccctc tgtttgatca
     1921 aaacattcat tacgctgatg tgggggacac aaaagcgaaa atgcagaaga aagccatttg
     1981 ctaaaattga acgattacta ctgggcgcgc agcaatttcg tgcgcccctc atttgcgcaa
     2041 tgtaagggtg tcatatgatt actattgacg gtaatggcgc ggttgcttcg gtggcgtttc
     2101 gcaccagtga agttatcgcc atctacccta ttacccccag ttccacgatg gcagaacagg
     2161 ctgatgcatg ggccggaaac ggcttgaaaa acgtttgggg agacacacca cgcgtggttg
     2221 aaatgcagtc ggaagcgggt gctatcgcta ccgtgcatgg tgctttgcaa actggtgccc
     2281 tctcaacatc gtttacgtca tcgcagggtt tgctgctgat gatcccaacg ctgtacaaac
     2341 tggcaggcga actcacaccg tttgtcctgc atgttgcggc acgtaccgtt gccacacatg
     2401 cactctctat ttttggcgat cattccgacg ttatggcagt gcgccaaacg ggttgcgcga
     2461 tgttgtgtgc agcaaacgtc caggaagcgc aagactttgc tctcatttcg cacattgcga
     2521 cgctgaaaag tcgcgtgcca tttattcatt tctttgatgg tttccgcaca tctcacgaaa
     2581 tcaataaaat tgtcccgctg gccgatgaca cgattcttga actgatgccg caggcagaaa
     2641 ttgatgctca tcgcgcccgg gcactcaacc cggaacatcc ggtgatccgc ggtacgtccg
     2701 ccaatcctga cacttatttc cagtctcgcg aagccaccaa cccatggtac aacgcggtct
     2761 atgaccatgt tgaacaggcg atgaatgatt tcgctgccgc gacaggtcgt cagtatcagc
     2821 cgtttgagta ttacgggcat ccgcaagcgg aacgggtgat tatcctgatg ggctctgcca
     2881 ttggcaccag tgaagaagtg gttgatgaat tgctgacccg tggcgaaaaa gtcggcgtgc
     2941 tgaaagttcg cctgtaccgc cccttctccg ccaaacactt gctgcaagct ctgccgggat
     3001 ccgtgcgcaa cgtggcggta ctggacagaa ccaaagaacc cggtgcccag gcagaaccgc
     3061 tctatctgga tgtgatgact gcactggcag aagcctttaa taatggcgag cgcgaaaccc
     3121 tgccccgtgt cattggtggg cgctatggtc tttcatccaa agaatttggc ccggactgtg
     3181 tactggcggt atttgccgag ctcaacgcgg ctaaaccgaa agcgcgcttt acggttggta
     3241 tttacgatga tgtaaccaat ctgtcactgc cgttgccgga aaacacccta ccaaactcgg
     3301 cgaaactgga agccttgttt tatggccttg gtagtgatgg cagcgtttcc gcgaccaaaa
     3361 acaatatcaa gattatcgga aattccacgc cgtggtacgc acagggctat tttgtttacg
     3421 actccaaaaa ggcgggcggc ctgacggttt ctcaccttcg cgtgagcgaa cagccgattc
     3481 gttccgctta tctcatttcc caggctgatt ttgttggctg ccaccagttg cagtttatcg
     3541 ataaatatca gatggctgag cgtttaaaac ctggcggcat tttcctgctc aacacgccgt
     3601 acagcgcagc tgaagtgtgg tcgcgcttgc cgcaggaagt tcaggccgtg ctaaaccaga
     3661 aaaaagcgcg cttctatgtg attaacgcgg cgaaaatcgc ccgcgaatgt ggcctggcgg
     3721 cccgtattaa taccgtcatg cagatggctt ttttccatct gacgcagatt ctgcctggcg
     3781 atagtgccct cgcagaattg cagggtgcga ttgccaaaag ttacagtagc aaaggccagg
     3841 atctggtgga acgcaactgg caggctctgg cgctggcacg tgaatccgta gaagaagttc
     3901 cactgcagcc agttaatccg catagcgcca atcgaccgcc ggtggtttcc gatgccgctc
     3961 ctgatttcgt gaaaaccgta accgctgcga tgctcgccgg gcttggcgac gccctccccg
     4021 tttcggcgct gccgccagac ggcacctggc cgatgggcac cacgcgctgg gaaaaacgca
     4081 atatcgccga agagatcccc atctggaaag aggaactctg tacccaatgt aaccactgtg
     4141 tcgccgcttg cccacactca gctattcgcg caaaagtggt accgcctgaa gcgatggaaa
     4201 acgcccctgc cagcctgcat tcgctggatg tgaaatcgcg tgatatgcgc gggcagaaat
     4261 atgtcttgca ggtggctccg gaagattgca ccggttgtaa cctgtgcgtc gaagtttgcc
     4321 cggcgaaaga ccgtcagaat ccagagatta aagccatcaa tatgatgtcg cgcctggaac
     4381 atgtcgaaga agagaaaatc aattacgatt tcttcctcaa cctgccagaa atcgatcgta
     4441 gcaaactgga acgtattgat attcgtacat cgcagctaat cacgccgctg tttgaatatt
     4501 ccggtgcttg ctccggttgt ggcgagacgc cgtatattaa attgctgact cagctctatg
     4561 gcgaccggat gttgatcgct aatgccactg gctgttcttc aatatacggc ggtaacctgc
     4621 cttcaacacc atataccacc gatgccaacg gtcgtggacc ggcatgggcg aactcgctgt
     4681 ttgaagataa cgccgaattt ggccttggtt tccgcctgac ggtcgatcaa caccgtgtcc
     4741 gcgtgctgcg tctgctcgat caatttgccg ataaaatccc gacggaatta ctgactgcgt
     4801 tgaaatcaga cgccacgcca gaggttcgtc gtgaacaggt agcagcttta cgccagcaac
     4861 tcaacgatgt tgccgaagca catgaactgc tgcgtgacgc agatgcactg gtggaaaaat
     4921 caatctggct gattggtggc gatggctggg cttacgatat cggctttggc ggtctggatc
     4981 atgtattgag tttgacggaa aacgtcaaca ttctggtgct ggatacgcaa tgctattcca
     5041 acaccggagg tcaggcatcg aaagcgacac cgctgggtgc agtaactaag tttggcgagc
     5101 atggcaaacg taaagcgcgt aaagatcttg gcgtcagtat gatgatgtac ggtcatgttt
     5161 atgtggcgca gatttctctc ggcgcgcagc tgaaccagac ggtgaaagcg attcaggaag
     5221 cggaagcgta tccggggcca tcgctgatca tcgcttatag cccgtgtgaa gagcatggtt
     5281 acgatctggc actcagccac gatcagatgc gccaactcac tgctaccggc ttctggccgt
     5341 tatatcgctt cgatcctcgt cgtgccgatg aaggcaaact gccgctggcg ctggattcac
     5401 gcccgccgtc agaagcactt gaagaaacgt tacttcacga gcagcgtttc cgtcgtctga
     5461 attcgcagca gccagaagtg gcagaacagt tatggaaaga tgctgcagct gatttgcaaa
     5521 aacgctatga cttcctggca caaatggccg gaaaagcgga aaaaagcaac accgattaaa
     5581 tgctctggat aaggattatc caattcaaaa aaaaagcccg gacgactgtt cgggcttgtc
     5641 ttcttatgtg ttggaaaatc agtagcaatg caatggccca acagaaaata aaatctgtga
     5701 caataaaggc atataacccg cgcagaataa cgtatagaaa attaaaagta taatttttat
     5761 tttgtatgtg ttatctccaa tacattcacc agacttatta tcatttcaga agaattattt
     5821 aattaaggtt ttacttaagg cgtaacaaat gatatttatc ggctaactga acttctcctt
     5881 taggatgttt tcactccccg aaatggggat gaaaggcaaa taaaataact aaaggattta
     5941 ttcaatgaaa agcaaagtac tggcactctt aattcctgcc ctgctcgctg caggtgctgc
     6001 acatgcagcc gaagtttata ataaagacgg caacaaattg gatctgtatg gcaaagttga
     6061 tggcctgcat tatttttctg ataattcagc gaaagatggc gaccagagct atgctcgtct
     6121 gggttttaaa ggcgaaaccc aaattaacga tcaactcact ggctacggtc aatgggaata
     6181 caatattcag gcaaacaaca ccgaatcttc aacaaaccag tcatggaccc gtctggcatt
     6241 tgccggactg aaatttgcag attacggttc tttcgattac ggacgtaatt atggcgtaat
     6301 gtacgacatc gaaggctgga ctgatatgct acctgaattt ggcggtgact cttataccaa
     6361 tgcagacaac tttatgactg gtcgtgccaa tggcgtcgcg acttatcgta atactgattt
     6421 cttcggtctg gtaaatggtc tgaacttcgc ggtgcagtat caaggtaaca acgaaggtgc
     6481 cagtaatggt caggaaggca ccaacaacgg acgtgatgtt cgccatgaaa acggtgacgg
     6541 ctggggtctt tccacaacat atgatttagg catgggcttt agcgctggtg cggcatacac
     6601 ctcttctgac cgcaccaatg accaggttaa ccatactgcg gcgggtggtg ataaagcaga
     6661 cgcgtggact gctgggctaa aatacgatgc taacaatatt tacctggcaa ccatgtattc
     6721 agaaacgcgt aatatgaccc cgtttggcga cagcgattat gctgttgcaa acaaaaccca
     6781 gaactttgaa gtcactgcac agtaccagtt tgattttggt ctgcgtccgg cagtctcttt
     6841 cctgatgtct aaaggccgtg acctgcacgc tgccggtggt gcagacaatc cggcaggtgt
     6901 tgatgataaa gatctggtta aatacgccga tgttggcgcg acttactatt tcaataaaaa
     6961 catgtccacc tatgttgact ataaaatcaa cctgttggat gaagatgaca gtttctacgc
     7021 tgccaacggc atctctaccg atgatattgt cgctttaggt ctggtttatc agttctaaat
     7081 ccccctgccc gctgttttgg cgggcttttt ctgcttattc ttcctccttt gatctaaatt
     7141 aaaaatgtga actccgtcat tacacaaaaa gtgtcatctg gcgttacact ttatgcggat
     7201 actaaaacag gaggttttat gaacagaacg attcttgtcc ctatcgatat ttccgattca
     7261 gaattaactc aacgcgtgat tagccacgtt gaggcagagg caaagattga tgatgcagag
     7321 gttcatttcc tgacggtaat accttcgctg ccctactatg cctctctggg tttagcgtat
     7381 tccgcagaat taccggcaat ggatgacctg aaagcggaag ccaaatcgca actggaagag
     7441 atcattaaaa aatttaaact gccaaccgac agagtgcatg tccatgttga ggaaggctcg
     7501 cccaaagacc gcattctgga attggcgaag aagatccccg ctcatatgat catcattgct
     7561 tcccatcgac cggatatcac cacttatctg ctcggttcta acgccgcagc tgtagtgcgt
     7621 cacgcagagt gctccgtgct ggttgtgcgc tgacactaac gcccgcacat tgctgcgggc
     7681 tttttgattc atttcgcaaa tgtgctgata ttttcccct
//
LOCUS       DAFGPF010000181         7682 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFGPF010000181 DAFGPF010000000
VERSION     DAFGPF010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7682
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.181"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..735
                     /locus_tag="LSX49_004828"
     CDS             <1..735
                     /locus_tag="LSX49_004828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HBL7171106.1"
                     /translation="KVFVVSVVAAACVFAVNAGAKEGKSGFYLTGKAGASVMSLSDQR
                     FLSGDEEETSKYKGGDDHDTVFSGGIAVGYDFYPQFSIPVRTELEFYARGKADSKYNV
                     DKDSWSGGYWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTTGIS
                     TWDYEYGSSGRESLSRSGSADNFAWSLGAGVRYDVTPDIALDLSYRYLDAGDSSVSYK
                     DEWGDKYKSEVDVKSHDIMLGMTYNF"
     gene            916..2415
                     /locus_tag="LSX49_004829"
     CDS             916..2415
                     /locus_tag="LSX49_004829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HBL7171107.1"
                     /translation="MNIRKLFCPGNTPRILLFLFFFVVSAITTIACGYTEKNATGNVL
                     LLFLLLLLAHRNTLTSITALLFLFCCALYAPAGMTYGKINNSFIVALLQTTTDEAAEF
                     TGMIPVYHFLVSAAILVFMVIFWRTHHRGHRNWLALLLFVLCSVNSWPLRMVKGIVVG
                     TTDTLREMQRYKQLNQHGADNWKILPGVPLYDTIVIVTGESVRRDYMSVYGYPVPTTP
                     WLNTAPGLFIDGYTSAAASTVPSLSRTLIYDYEQNPDSGNNVVALAAKAGYSTWWISN
                     QGKLGEHDTRISVIASDAEHTVFLKKGSFASRKTDDMLLLQETERALADKSSPKVIFL
                     HMMGSHPNPCDRLHSWPNHYLEQYPRKVACYLASISKLDNFLGQLDGILRRHSRHFAM
                     LYFSDHGLSVSDSANPVHHDGHVQGGYSVPLIITASDITSHQSVSRKISARHFAGIFQ
                     WLTGIRTENIPPFNPLTDEDNEPVMVFNGERNVPADSLKPQPLILPDRR"
     gene            complement(2524..6040)
                     /locus_tag="LSX49_004830"
                     /pseudo
     CDS             complement(2524..6040)
                     /locus_tag="LSX49_004830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708739.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(6492..>7682)
                     /locus_tag="LSX49_004831"
     CDS             complement(6492..>7682)
                     /locus_tag="LSX49_004831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HBL7171108.1"
                     /translation="GMFLLVHPNGSRYWRLRYRILGKEKTLALGVYPEVSLSEARTKR
                     DEARKLISEGIDPCEQKRVKKVVPDLQLSFEHIARRWHASNKQWAQSHSDKVLKSLET
                     HVFPFIGNRDITTLSTPDLLIPVRAAEAKQIYEIASRLQQRISAVMRYAVQSGIIRYN
                     PALDMAGALTTVKRQHRPALDLSRLPELLSRISSYKGQPVTQLAVMLNLLVFIRSSEL
                     RYARWSEIDIDNAMWTIPAEREPLPGVKFSHRGSKMRTPHLVPLSKQAVAILTELQTW
                     AGENGLIFTGAHDPRKPISENTVNKALRVMGYDTTQEVCGHGFRAMACSALIESGLWS
                     RDAVERQMSHQERNGVRAAYIHKAEHLEERRLMLQWWADFLDANREKGISPFEYAKIN
                     NPLK"
BASE COUNT         1956 a         1862 c         1730 g         2134 t
ORIGIN      
        1 aaggtttttg ttgtttcagt ggtggccgca gcctgtgtat ttgcagtaaa tgcaggagca
       61 aaggaaggta aaagcggttt ttatctgacc ggtaaagccg gtgcctctgt gatgtcactt
      121 tcagaccagc gtttcctgtc aggagatgag gaagaaacat caaagtataa aggcggcgat
      181 gaccatgata cggtattcag tggcggtatt gcggtcggtt atgattttta tccgcagttc
      241 agtattccgg ttcgtacaga actggagttt tacgctcgtg gaaaagctga ttcgaagtat
      301 aacgtagata aagacagctg gtcaggtggt tactggcgtg atgacctgaa gaatgaggtg
      361 tcagtcaaca cactaatgct gaatgcgtac tatgacttcc ggaatgacag cgcattcaca
      421 ccatgggtat ccgcagggat tggctacgcc agaattcacc agaaaacaac cggtatcagt
      481 acctgggatt atgagtacgg aagcagtggt cgcgaatcgt tgtcacgttc aggctctgct
      541 gacaacttcg catggagcct tggcgcgggt gtccgctatg acgtaacccc ggatatcgct
      601 ctggacctca gctatcgcta tcttgatgca ggtgacagca gtgtgagtta caaggacgag
      661 tggggcgata aatataagtc agaagttgat gttaaaagtc atgacatcat gcttggtatg
      721 acttataact tctgacgaca ctgctcctga acgataattg cgtatattct gtaattaaga
      781 taattgcata tcttctgcaa ttaaacagaa ataccctgca gtctattact gcagggttgt
      841 ctgttatctg ttttacagat aattctgatt tttattatcc tgttctcttc ataataatgt
      901 tgtcgatata ctccgatgaa tatcagaaaa ctgttttgtc cgggaaacac cccccggatt
      961 ttattgtttt tattcttttt tgttgtttct gcaataacca caattgcatg cggatacact
     1021 gagaagaatg caacaggaaa tgtgctgctt ctgtttctcc ttctgctcct tgcacacaga
     1081 aataccctca catccattac agcgctgtta tttctgttct gttgtgcact gtatgcgcct
     1141 gccggtatga cgtacggtaa aatcaacaac agttttattg tcgcgttgtt gcagaccaca
     1201 actgatgagg cagcggagtt taccgggatg attcctgttt atcattttct ggtcagtgcc
     1261 gcgattctgg tattcatggt gattttctgg cgaacacacc accgcggtca ccgtaactgg
     1321 ctggcactgc tgctgttcgt attatgctca gtaaacagct ggccgttgcg gatggttaaa
     1381 ggaattgttg tggggacaac tgacacattg cgtgaaatgc agcgttataa acaactgaat
     1441 cagcacgggg ctgacaactg gaaaatcctg ccgggtgtac cgttgtatga cacgattgtt
     1501 atcgtcactg gtgagagtgt gcgcagggat tatatgtcgg tatatggcta tcctgtgcca
     1561 accacaccgt ggctgaatac ggctcccggt ttatttattg acggttatac atcggcagca
     1621 gccagtactg tgccttccct gagccggaca ctgatttatg actatgagca gaaccctgat
     1681 tccggcaaca acgtggtggc gctggcagca aaagcaggat acagcacatg gtggatatcc
     1741 aatcagggaa aactggggga gcatgataca cgcatctctg ttattgcttc tgatgcggag
     1801 cataccgttt tcctcaagaa aggcagcttt gcttcccgta aaacggatga catgttgttg
     1861 ttacaggaaa cagaacgtgc actggcggat aaatcctctc cgaaggtgat tttcctgcac
     1921 atgatggggt ctcatccaaa cccgtgtgac cggcttcact cctggccgaa tcattacctg
     1981 gagcagtatc cccgaaaggt tgcctgttac ctcgccagca tcagtaaact ggataacttt
     2041 ctcggtcagc ttgatggtat ccttcgccgg cattcccgtc attttgccat gctttacttt
     2101 tctgaccatg gtctgtcggt cagcgacagt gctaatcctg ttcatcatga tggtcatgtg
     2161 cagggaggct acagcgttcc cctgattatt accgccagtg acatcacgtc tcatcagtcc
     2221 gtcagcagaa aaatcagtgc ccgtcatttc gcaggtattt ttcagtggct gaccggcatt
     2281 cgtactgaaa atataccgcc attcaatccg ctgacagacg aagataatga acccgttatg
     2341 gtttttaacg gggagaggaa tgtaccggca gacagtctga aaccgcagcc tctgattctt
     2401 ccggacagaa gataatcatg tcggtatgaa tgttataatt aaggaccgtg caataatagc
     2461 cattccattc agccatctta cgctcgaaaa caatcggtaa gatggctact caccattcct
     2521 gctctaaacc tgacgcctct caagactatt ataaatagcc tcaacctcac ccttcaggtt
     2581 atcaccgcaa taaaccattg aggtatcgta tcgttcatat cgcgcttccc gtgtcgcact
     2641 aaaccagttg aacgatccca cgcacagcaa accatcatca ccaataacaa ttttgctatg
     2701 aacacggttt accagctttg tagcaatacc cagcgcattc agtttctcca gcgccgcttt
     2761 aaagttttgc tgcttctctt ttcgcttctc aaaatcatta tgttcagtgt tgtagcttct
     2821 gtcagtgact atcgtgacgt taactccacg tgaacacgcc gcaatcatgg aatcaagaaa
     2881 accggtttgc tccagccttt gccaggtcag ccatggagaa actatcatga tgtgtttact
     2941 ggtattttca aatgtctgat tcaggaaatt atcatgttgc tccacaccat gaagtgtgta
     3001 gattttggtc ccggcggttt ttaaatcctt acgctcttta taatcaaaag agagcgcatt
     3061 cttctctgac tcaaagaggt attttgccag taatccccgt ggagatgagg ctggctggac
     3121 ctcaaacagg tccatatcgc cgaagaccag aaaactgtcc ttcgcacggg agactgcaac
     3181 attcagcatg ctgttatcgc tatcaataaa cccgccgtct tcatgttttg aatagactgg
     3241 cgagaatatc acaatcgctc tttccgctcc ctgaagagag tgcacggtgc ccactgtgag
     3301 cgatttttca ttcgcgcctg tactgatacc ttgtttgccc agcacctgtt tgatagtgga
     3361 tacctgagcg ctaaaaggcg tcacgatacc gacaacttca tgaagcgatt taccgtaatg
     3421 cgcttcaata ttttgctggt tctctgccaa ccagaccgct atcgtttcag cctcaagcaa
     3481 attatatcga cttccactac ttgccagctc acctttacca tcaatatgga gataccccat
     3541 ttcgggcatt aaattgctct cttcacgccc tcttttaggc aacaacttac cgtgatagca
     3601 gagcgtatta cagtatccaa taatattgtc gtagcaccgg cggtgttcat ataggtacat
     3661 accacgagcc agttcgggat catattgata gcgtgaagca aactgcgcta ttttcataac
     3721 gctgccagat tgcggcactt ttaccaaggt ctgcgattgc cgtatatttc tcggtaatct
     3781 cttcttgcgt actgccagac agaatttttt ccgccagcat gttaccgaca tcaatcgcag
     3841 gagcaatact ccatattggc gggagctgct ccgtatcgcc aatcactaat gccttcttag
     3901 ctaatgcaaa cgaggcagca gccacttcag gaagcacctg cccggcttca tcgacaatga
     3961 gtaaatcggc aaaatcatac aaataacttt tctcgaattt acgctgtcct ttgtgctcac
     4021 ttatctgcat attgccgggc agcatatagc atgtcatcac cacacatgga gtgagtttca
     4081 ttcgacgttg ccaacgggcg gttacccctt tagcgccttt tttcttcttc tcttcctgca
     4141 gatcatcaat gctggccata tccatcagcc aacgaccttc ccagtagtga gtcgtcagta
     4201 aaaatgcagg gaagcgaatc tgcgtatcag ccagttcatc ggcctgtgag aagctcagtt
     4261 cctcgtcgcc ctcataccct aaatcaagag ccagtctctg ccactcctga accgcctgct
     4321 gttctttaag aatgatttca tgggcggagt caatctgctg ccggtatgtt gtttgctcgc
     4381 gctcagcgga attgagcagc ccatcaatat tacgttcgat agtttcagga tcagaccact
     4441 gatttcctgc aatcagcgcc cctaatttat cttcgagaaa cagttgtatt tggtactgtc
     4501 gcttactgcg aaccgccggg agccaggaaa ataatgaata gatcagtgat tcaccggcgc
     4561 gatatttttt ccattccgtt ttagcacttt tcagtagagt gattttttgt tcttgtccgg
     4621 aaagtaattt atttaaatta tcgagatatt gctcaatgtc gttagcaata agctcacgcg
     4681 cagcccatac ctggcttaac gtttgccatg ttgcgttcag tcttatcagt tgctcggatt
     4741 ttgctgccaa ctgaccatgc aggagttcaa tgaccttttc aggggatgaa cactcttttt
     4801 caggaaaagc tgccttagct ttctcgagat aaaacagcag tgcatcttct acatactctt
     4861 ttgactcaac ctggttgaag aaatcttcag tttgatattt tttggctgct tcagctttac
     4921 ggctgcttga gggaaaataa gcgccgaagc ttttcagctc tggcaaccat cgcccggcca
     4981 tcgcacctga accttgcgaa aagtctttcc cgaatgcctc aataatgttc gttacagcct
     5041 ggttattcgt tgaagtcgcg ataataaccg gaggctcaga tttttcgaga gccgctctgg
     5101 cccactgcgt ggcgatgata gaaagcacca gcgtggtttt tccggttccc ggagggccat
     5161 taacagcaag gatatcgcca tgtctagcat ccagaaaatg gcttaaggca tcgcgctgag
     5221 cctttgccag cggaaactta tctccggagt gtccaagcct gtcgctgaat tttgctccag
     5281 gggccagcaa agactctgca gcatgaacct ctcgcgaggc gaagcgattg aagagcggca
     5341 catccttatt gcaaacaagc aggtgatcat aaagagaaag gatatggaaa ctggcaccgc
     5401 cagattgagc cgttttaaca atataaccgt gctcagcgag ttcatattgc tcaggttttt
     5461 caatccagtc gccggcaacg ctcttcagta gcctctctga gtcatacaga tattgacgcc
     5521 actcctgctg caaggcggca tatcgtgctt cccgttcttc atccgtttcg gcagtcttat
     5581 caacgctgtc atcaaagttg atagagaacg tggtatgggt cgtcttgtat ttgtcatact
     5641 gcccaatctc accaatcgaa aatgctcctt ttggcaaagg ttcaagcagg tctctgggaa
     5701 tggaggtcgc tggcgtcgga tataaaaaac cctcacggct tagcaaggct ggcgtcacta
     5761 tcggggtaac aatatcaggc gcacctgcag aacggtcctt accatgctgc aataaccgga
     5821 aataaacttt tgggcgcaag atgacatcga ccgtttcgac atcgtctttt tctcccttaa
     5881 aaaatttact gacaatcgct tcgtcaagac gtcccgccgc tatcccatgc cagtgagtga
     5941 aatttttggc gtctttccgt tcaaaactgc cctttcctga ctcagcatcc gcaagcgagt
     6001 tgcgccagta tgaggtaaac cctaaagcat tttcatccat taccagtcct gtgactcaat
     6061 gaaatccatt gatttatcga atataaaacc accgtatgga caactattgt ccatattgaa
     6121 aaagttggat gcaatgtttt gtttataatt cggtatcaaa tgtactggtt gtacaaggtt
     6181 cagaacacaa gcacattcaa cagtacgtca ggactattga tttcataaca gtgaatacat
     6241 tttttaccgt ttataatgac tgcctgtgtt ggacaaggat accagaacag ccgaaaacac
     6301 cgggggttat tacctgctct catggaaacc agatattcct ggtgctaatc acagtcataa
     6361 atagcctgaa gaacatgacg aagggacttt aatggacgcc ggagtaactt gtcagaacat
     6421 caatcttcgt catcatttac aaagaaaaat aatcagttaa agcagtccgg gcaatcagcc
     6481 cggactgctt actattttaa tggattgtta atctttgcat attcaaacgg actgataccc
     6541 ttctcccggt tcgcatccag aaaatcggcc caccattgca acatcagtcg ccgttcttcc
     6601 agatgttctg ctttatggat atacgcagca cgtacaccat tacgctcctg atggctcatc
     6661 tgacgttcca cagcatcgcg ggaccacaaa cctgattcaa tcaatgcact gcacgccatc
     6721 gcccggaatc catggccaca gacttcctgg gttgtgtcat accccatcac cctcagggcc
     6781 ttatttacag tattttcact gattggttta cgcgggtcat gtgcacccgt aaatatcaga
     6841 ccattttcac cagcccatgt ctgaagttct gtcagtatgg ctacagcctg tttgctgagt
     6901 ggcacaagat gtggtgttcg catcttggag ccccggtgtg agaattttac gccgggcaga
     6961 ggttcgcgtt cggctggaat agtccacatg gcattgtcaa tatcaatttc agaccaccgg
     7021 gcgtatctga gttcactgga acgaataaaa accagtaaat tcagcataac ggcaagctgg
     7081 gtgacaggtt gccccttgta actgctaata cgcgacaaaa gttcaggcag gcgagaaaga
     7141 tcaagagcgg ggcgatgctg gcgttttacc gtggtcaatg caccagccat atccagagcc
     7201 gggttatatc tgatgatgcc agactgtacg gcgtaacgca ttacagcaga tattctttgc
     7261 tgcagacgac tggcgatttc ataaatttgt tttgcttctg cagcacgaac aggaataagc
     7321 aggtccgggg tactgagtgt tgtgatatcc cggttgccga taaaggggaa aacgtgtgtc
     7381 tcgaggcttt tgagtacttt atcgctgtgt gattgtgccc attgtttatt actggcatgc
     7441 cagcgtcgtg caatatgttc aaaagagagc tgtaaatcag ggactacttt tttaactctt
     7501 ttctgttcgc aagggtcaat cccctctgaa atcagttttc gggcctcatc ccgttttgta
     7561 cgagcttcgg agagagaaac ttccggatac acaccaagtg ccagggtttt ctccttaccc
     7621 agaatacgat aacggagacg ccagtaacgg gaaccattag gatgaaccag caggaacatg
     7681 cc
//
LOCUS       DAFGPF010000182         7587 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFGPF010000182 DAFGPF010000000
VERSION     DAFGPF010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7587
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.182"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..2558
                     /gene="cnf1"
                     /locus_tag="LSX49_004832"
     CDS             <1..2558
                     /gene="cnf1"
                     /locus_tag="LSX49_004832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_111779456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cytotoxic necrotizing factor CNF1"
                     /protein_id="HBL7171109.1"
                     /translation="ISSALYLYKNGELDEREYNFSMNALNRSDNISLLFFDIYGYYAS
                     DIFVAKNNDKVMLFIPGAKKPFLFKKNIADLRLTLKELIKDSDNKQLLSQHFSLYSRQ
                     DGVSYAGVNSVLHAIENDGNFNESYFLYSNKTLSNKDVFDAIAISVKKRSFSDGDIVI
                     KSNSEAQRDYALTILQTILSMTPIFDIVVPEVSVPLGLGIITSSMGISFDQLINGDTY
                     EERRSAIPGLATNAVLLGLSFAIPLLISKAGINQEVLSSVINNEGRTLNETNIDIFLK
                     EYGIAEDSISSTNLLDVKLKSSGQHVNIVKLSDEDNQIVAVKGSSLSGIYYEVDIETG
                     YEILSRRIYRTEYNNEILWTRGGGLKGGQPFDFESLNIPVFFKDEPYSAVTGSPLSFI
                     NDDSSLLYPDTNPKLPQPTSEMDIVNYVKGSGSFGDRFVTLMRGATEEEAWNIASYHT
                     AGGSTEELHEILLGQGPQSSLGFTEYTSNVNSADAASRRHFLVVIKVHVKYITNNNVS
                     YVNHWAIPDEAPVEVLAVVDRRFNFPEPSTPPDISTIRKLLSLRYFKESIESTSKSNF
                     QKLSRGNIDVLKGRGSISSTRQRAIYPYFEAANADEQQPLFFYIKKDRFDNHGYDQYF
                     YDNTVGLNGIPTLNTYTGEIPSDSSSLGSTYWKKYNLTNETSIIRVSNSARGANGIKI
                     ALEEVQEGKPVIITSGNLSGCTTIVARKEGYIYKVHTGTTKSLAGFTSTTGVKKAVEV
                     LELLTKEPIPRVEGIMSNDFLVDYLSENFEDSLITYSSSEKKPDSQITIIRDNVSVFP
                     YFLDNIPEHGFGTSATVLVRVDGNVVVRSLSESYSLNADASEISVLKVFSKKF"
     gene            complement(2796..3414)
                     /locus_tag="LSX49_004833"
                     /pseudo
     CDS             complement(2796..3414)
                     /locus_tag="LSX49_004833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            3478..4326
                     /locus_tag="LSX49_004834"
                     /pseudo
     CDS             3478..4326
                     /locus_tag="LSX49_004834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612091.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4739..5101
                     /locus_tag="LSX49_004835"
     CDS             4739..5101
                     /locus_tag="LSX49_004835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL7171110.1"
                     /translation="MVKLASQPGASVARIAREHDINDNLLFKWLRLWQNEGRISRRLP
                     VTTSSGAGVELLPVEITPDEQKEPVAALTPLLSTPSQSTVSASSCKVEFRHGNMTLEN
                     PSPELLTVLIRELTGRGR"
     gene            5098..5448
                     /gene="tnpB"
                     /locus_tag="LSX49_004836"
     CDS             5098..5448
                     /gene="tnpB"
                     /locus_tag="LSX49_004836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL7171111.1"
                     /translation="MISLPSDTRIWLVAGVTDMRKSFNGLGEQVQHVLDENPFSGHLF
                     IFRGRRGDTIKILWADADGLCLFTKRLEEGQFIWPAVRDGKVSITRSQLAMFLDKLDW
                     RQPKTSRLNALTML"
     gene            5479..7092
                     /locus_tag="LSX49_004837"
     CDS             5479..7092
                     /locus_tag="LSX49_004837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL7171112.1"
                     /translation="MSRKYLIRITELERLLSEQAEALRQKDQQLSLVEETEAFLRSAL
                     ARAEEKIEEEERETEHLRAQIEKLRRMLFGTRSEKLRREVEQAEALLNQRRQDSDRYS
                     GWEDDPQVPRQLRQSRHRRPLPAHLPREIHRLESEESCCPECGSELDYLGEVSAEQLE
                     LVSSALKVIRTVRVKKACTKCDCIVEAPAPSRPIERGIAGSGLLARVLTGKYCEHLPL
                     YRQSEIFARQGAELSRALLSNWVDACCQLMTPLNDALYRYVMNTRKVHTDDIPVKVLA
                     PGRKKAKTGRIWTYVRDDRNAGSSEPPAVWFAYSPDRQGKHPVQHLRPFRGILQADAF
                     SGYDRLFSAEREGGALTEVACWAHARRKIHDVYISSKSTTAEEALKRISELYAIEDEI
                     RGLPESERLAARQQRSKALLTSLHEWMVEKNGTLSKKSRLGEAFSYVLNQWDALCYYS
                     DDGLAEADNNTAERALRAVCLGKKNYMFFGNDHGGERGALLCGLIGSCRLNGIDPEAY
                     LRHILSVLPEWPSNRVDELLPWNVVFTDK"
BASE COUNT         2061 a         1730 c         1833 g         1963 t
ORIGIN      
        1 atatttcttc tgctttgtat ctttataaaa atggagagct tgatgagcgt gaatataatt
       61 tctccatgaa cgccttaaat cgcagtgata atatatcact attattcttt gatatttatg
      121 gatattacgc atctgatatt tttgtagcca aaaataatga taaggtaatg cttttcattc
      181 ctggtgcaaa aaaacctttt ttattcaaga agaatatcgc tgatttgcgg cttaccctta
      241 aagaacttat taaggatagt gacaacaaac aattactttc ccaacatttt tcattatata
      301 gtcgtcaaga tggagtttcc tatgcaggag taaattctgt tctacatgca atagaaaatg
      361 atggtaattt taatgagtct tactttctgt attccaataa gacacttagc aataaagatg
      421 tttttgatgc tatagctatt tctgttaaga aacgcagttt cagtgatggt gatatcgtta
      481 taaaatcaaa cagtgaagct caacgagact atgctctgac tatactccag acgattttat
      541 caatgacccc tatatttgat atcgtagtcc cggaggtatc tgttccgctt ggactgggga
      601 ttattacttc cagtatgggg atcagttttg atcaactgat taatggtgat acttatgaag
      661 aacgtcgttc tgctatacct ggtttggcga caaatgcagt attgcttggt ctgtcttttg
      721 caattccact cttgattagt aaggcaggaa taaaccagga ggtacttagc agcgttataa
      781 ataatgaggg caggactctg aatgaaacaa atatcgatat atttttgaag gaatatggaa
      841 ttgctgaaga tagtatatcc tcaactaatt tgttagacgt taagcttaaa agttccgggc
      901 agcatgtcaa tattgtaaag cttagtgatg aagataatca aattgtcgct gtaaaaggga
      961 gttctctgag cggcatctac tatgaagtgg acattgaaac aggatatgag attttatccc
     1021 gaagaattta tcgtaccgaa tataataatg aaattctctg gactcgaggt ggtggtctaa
     1081 aaggggggca gccatttgat tttgaaagtc tcaatattcc tgtatttttt aaagatgaac
     1141 cctattctgc agtgaccgga tctccgttat catttattaa tgatgacagc tcacttttat
     1201 atcctgatac aaacccaaaa ttaccgcaac caacgtcaga aatggatatt gttaattatg
     1261 ttaagggttc tggaagcttt ggggatagat ttgtaacttt gatgagagga gctactgagg
     1321 aagaagcatg gaatattgcc tcttatcata cggctggggg aagtacagaa gaattacacg
     1381 aaattttgtt aggtcagggc ccacagtcaa gcttaggttt tactgaatat acctcaaatg
     1441 ttaacagtgc agatgcagca agcagacgac actttctggt agttataaaa gtgcacgtaa
     1501 aatatatcac caataataat gtttcatatg ttaatcattg ggcaattcct gatgaagccc
     1561 cggttgaagt actggctgtg gttgacagga gatttaattt tcctgagcca tcaacgcctc
     1621 ctgatatatc aaccatacgt aaattgttat ctctacgata ttttaaagaa agtatcgaaa
     1681 gcacctccaa atctaacttt cagaaattaa gtcgcggtaa tattgatgtg cttaaaggac
     1741 ggggaagtat ttcatcgaca cgtcagcgtg caatctatcc gtattttgaa gccgctaatg
     1801 ctgatgagca acaacctctc tttttctaca tcaaaaaaga tcgctttgat aaccatggct
     1861 atgatcagta tttctatgat aatacagtgg ggctaaatgg tattccaaca ttgaacacct
     1921 atactgggga aattccatca gactcatctt cactcggctc aacttattgg aagaagtata
     1981 atcttactaa tgaaacaagc ataattcgtg tgtcaaattc tgctcgtggg gcgaatggta
     2041 ttaaaatagc acttgaggaa gtccaggagg gtaaaccagt aatcattaca agcggaaatc
     2101 taagtggttg tacgacaatt gttgcccgaa aagaaggata tatttataag gtacatactg
     2161 gtacaacaaa atctttggct ggatttacca gtactaccgg ggtgaaaaaa gcagttgaag
     2221 tacttgagct acttacaaaa gaaccaatac ctcgcgtgga gggaataatg agcaatgatt
     2281 tcttagtcga ttatctgtcg gaaaattttg aagattcatt aataacttac tcatcatctg
     2341 aaaaaaaacc agatagtcaa atcactatta ttcgtgataa tgtttctgtt ttcccttact
     2401 tccttgataa tatacctgaa catggctttg gtacatcggc gactgtactg gtgagagtgg
     2461 acggcaatgt tgtcgtaagg tctctgtctg agagttattc tctgaatgca gatgcctccg
     2521 aaatatcggt attgaaggta ttttcaaaaa aattttgatt cgggaaatta tttattggcc
     2581 attgttatag ttactccctt gtgctgtttt gttagcgcaa gagagtgtca gttctgcatt
     2641 ttgatatatt caagtcacca tcctccaaag gcaaacaaat gagaaaaggt catcaggcac
     2701 aaacatccag tgaaaagctc cccagtcttc tcctgctggc ttctgccccc tactttgcca
     2761 caatactctg tgcccctgtc ggtcagtatt ctctacattg gcaggtcatg cgactcataa
     2821 aatggcagta cacgatcatt cagcaggcca gtcgctgtaa tcgcattttg gtgacataca
     2881 atttgcagtg aacgaccttt gagtatgtat caacaaaggt ctggtgataa attacgcgac
     2941 acctttcagg ttgcctacat agaacgtgtc ctgcgaaccc agatatcccg gatgagccgt
     3001 ttcgatttcg ccacaggcct cgtcatcact ggctttacgc tccagtgctg cgatctggct
     3061 gtcagttagc tcaatgccat cacgggctac tttttcttcc agtgctttca gacgtttttt
     3121 gaaattctca aggttatggc gtaaccagac agaacggaca ccactgccgg agataaaaac
     3181 gccctgttta cgcagcttgt tgctggtccg gtgctgaccg tgtgccggga aagcgacggc
     3241 gtaatcaaca acagcctgtt cagttgcctc atcggtacgg ttcttaaggt taggagcgcg
     3301 gcgactacga ttaatcagcg catccacacc gccttcatcg accagttcgc ggtaacgata
     3361 aaatgtatca cgcgaaacgc ccatgatttt acagactttt gatacgttgc tgagtgatct
     3421 tacccaccaa tagtggacac aggactaagt gagtaaactc tcaaccagag gtgactcatg
     3481 acaaaaccag tatcaatcag caagaagccc cgtaaacaac atacgcctga atttcgtaac
     3541 gaagccctga aactcgctga acgcatcggt gtggccgccg cagcccgtga actcagcctg
     3601 tatgaatccc agctttatgc ctggcgcagt aaacagcagc aacaaatgag ttcgtcagag
     3661 cgcgaaagcg aactggccgc tgaaaatgtc cgccttaaac gacaactggc ggagcaggct
     3721 gaggaactgg ccatcctcca aaaggccgcg acatacttcg cgaagcgcct gaaatgaagt
     3781 atgtcttcat cgaaaatcat cgggcagagt tcagcatcaa agcgatgtgt cgtgtacttc
     3841 gggttgcccg cagcggctgg tatgtctggc tcaggcgtcg tcaccagatg agcctgcgcc
     3901 aacagtttcg gctcacctgc gatgccgctg tccataaggc attctttgag gcaaagcagc
     3961 gatacggtgc tccccgcctt gctgacgaaa tgctggagtt caatatttaa aaccattgct
     4021 gccagcctgc gtcgtcaggg gctgcgggcg aaagccagcc ggaagttcag cccggtcagc
     4081 taccgtgcac atggcctgcc cgtattggag aatctgctgg agcaggactt cagcgccagc
     4141 ggcccgaacc agaagtgggc gggtgacatc acgtacttgc gtaccgatga gggctggttg
     4201 tatctcgcag tagtcatcga cctgtggtca cgcgccgtta ttggctggtc gatgtcaccg
     4261 cgaatgacag cacaactggc ctgtgatgca ctgcaaatgg cgttgtggcg gagaagacgc
     4321 ccggaatgtc agcgccagtg atataagacg gtaattcacc atttggattg tccgctccac
     4381 ccaacatgtt gtttccttaa ggttctcaca ccagaaagtt tcatccattt tcttccaccc
     4441 aagttgcgga agagccgctt ttcatccgtc gttgacagct atgatgtcgg aaatctgtga
     4501 ggcaccacac actcctgctt tttccttcat ccgtcaccat gctcttcagt taattgtagg
     4561 acgtgtttat tacatttctg taagcgtaaa ctgaccgccg tatgtagcca ttaagccagt
     4621 attggtaacg taggtgccca ctttttcaac tagtggacac ctgttatgga acagaaaata
     4681 ttatccgcag aaccccgcag aaccccgcag aacattttca aatgagttta aacttcaaat
     4741 ggttaaactg gcttcacaac caggagcctc tgttgcccgt attgccaggg aacacgatat
     4801 caatgataac ctcctgttca aatggctcag gctctggcag aacgaagggc gtatatcgcg
     4861 gcgtcttccg gtaacaacct cttctggcgc tggcgttgaa ttattacctg ttgagataac
     4921 gcctgatgag cagaaagagc ctgtggcggc tcttactccg cttttatcca ctccttcaca
     4981 aagcacagtc agtgccagtt cctgtaaagt tgagttccgc cacggtaaca tgacgctgga
     5041 aaatccgtca ccagagctgc tcacggtgtt gatccgtgaa ctgaccggga gaggacgatg
     5101 atctcgctcc catcagacac tcgaatctgg ctggttgccg gcgttactga tatgcgtaaa
     5161 tccttcaacg gtctgggtga acaggtacaa catgtgctgg atgagaaccc cttctccggt
     5221 cacctgttta tctttcgcgg ccgacggggt gacacgatta aaatcctgtg ggctgatgct
     5281 gatggtctgt gcctgttcac caaacgtctg gaggaaggcc agtttatctg gcctgcggtg
     5341 cgtgacggta aggtatccat tacccgctcg cagctggcaa tgttcctcga taaactggac
     5401 tggcgtcaac ccaaaacatc ccgccttaat gcactgacaa tgttgtaaaa atgtcatggc
     5461 cggattataa aaacggtcat gagtcggaaa tacctcattc gtatcactga gctggaaagg
     5521 ctactctctg agcaggctga agccctccgt cagaaagatc agcaactgag tctggttgaa
     5581 gagacggagg ccttcctgcg ctctgcactg gcacgtgccg aagaaaagat cgaagaggag
     5641 gagcgggaaa cagaacatct gagggcccag atagaaaaac tgcgccggat gctgttcggt
     5701 acccgttctg aaaaactgcg tcgtgaagtt gaacaggctg aggccctgct gaatcaacgc
     5761 cgacaggaca gcgatcgtta cagtgggtgg gaagacgatc cgcaggttcc ccgccagttg
     5821 cgacagtcgc gccatcgtcg tccgttaccg gcacaccttc cccgtgaaat acaccgtctg
     5881 gagtctgaag aaagctgttg cccggagtgt ggcagtgagc tggattatct gggtgaagtc
     5941 agtgctgagc agctggaact ggtgagtagc gccctgaaag tgatccgcac tgttcgggta
     6001 aaaaaagcct gtacaaaatg tgactgtata gttgaagcgc cagcgccgtc ccgcccgata
     6061 gagcgcggca tcgcgggctc cggattactt gcccgcgtgt taacgggaaa atactgcgaa
     6121 cacctgccac tgtatcgtca gagtgaaatc tttgcccgac agggtgccga actgagccgt
     6181 gcattactct ccaactgggt tgacgcgtgc tgccagttaa tgactccgct gaatgatgcc
     6241 ctgtaccgtt acgtgatgaa cacccgcaag gttcacactg acgacatacc agtaaaagtg
     6301 ctggcaccgg gcagaaaaaa ggcaaaaaca ggacgcatct ggacgtatgt ccgggatgac
     6361 cggaatgcgg gctcatcaga gccaccggcg gtctggttcg cctactcacc agacaggcag
     6421 ggaaaacatc cggtacaaca ccttcgtccc ttccggggta tcctgcaggc ggatgcattc
     6481 agcggttacg atcggctgtt cagtgccgaa cgtgaaggtg gtgcactgac agaagttgcg
     6541 tgctgggccc atgcccggcg aaaaatccac gatgtataca tcagcagcaa aagtacgacg
     6601 gcagaagaag ctctgaagcg catcagtgaa ctgtacgcca ttgaggatga aatacggggc
     6661 ttaccggagt ctgaacgtct tgcagccagg cagcagcgaa gcaaagcgtt actgacgtcg
     6721 ctgcatgaat ggatggtgga gaagaatggc acgttgtcga aaaaatccag actgggcgaa
     6781 gcgttcagct atgtcctgaa tcagtgggac gccctctgtt attacagtga tgacggtctg
     6841 gcggaggcgg acaataacac agcagaaaga gcgcttcgtg ccgtctgtct cgggaaaaag
     6901 aattacatgt tcttcggcaa cgatcatgga ggcgagcgcg gagctctgct gtgcggacta
     6961 atcgggagct gtcggttgaa cggtatcgat ccagaagcgt atctgcgcca tatcctgagc
     7021 gtactgccgg aatggccctc caaccgtgtt gacgaactgc tgccatggaa cgtagttttc
     7081 accgataaat aagtgtcaat acggcgctct gttgacgctt acacatttct cccccgctca
     7141 atatctggca gagggcatga atacggaacg tgacttcgca ctgcttgcaa catttttgtg
     7201 atgaggacag actgcgtaat tggaaatggt gcagtcacac tcaggaatgg ctgtatgata
     7261 ttcggggagc aggattagat gacttcatcc tcccggatat gtattacgtt tactactact
     7321 acgcctctga attaacagaa tgatggtaac ggaagaaaat gccggaaagg gcagaaagcg
     7381 gaagtcttga ggctggcaga caatgctgga gctggacttt cagacaacaa aaaacatcac
     7441 cgttctcacc cctgcctgac acacaggtct tctgagcgcc cagagcccat tttatccggg
     7501 atggtgggac ttgccatccc tgtctgcttc atccacccgg cggcattatt gattgtgatg
     7561 gagagttcat caccaccagg ggcggac
//
LOCUS       DAFGPF010000183         7585 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFGPF010000183 DAFGPF010000000
VERSION     DAFGPF010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7585
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.183"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            214..4461
                     /gene="fdeC"
                     /locus_tag="LSX49_004838"
     CDS             214..4461
                     /gene="fdeC"
                     /locus_tag="LSX49_004838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like adhesin FdeC"
                     /protein_id="HBL7171113.1"
                     /translation="MSRYKTDNKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMENTTVTANNNVEKNVASLAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKNFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSENDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAITAEVNYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRE
                     RRMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTVSLGLVVSKATHGLK
                     NVQWEAPSLLAAGGKITGQGNQWQVTLPAYQAGKDNYYAISAIAYDNKGNASKRVQTE
                     VVISGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLRDAEGQPVTGMKDQIKTEL
                     TFKPAGNIVTRTLKATKSQAKPTLGEFTETESGVYQSVFTTGTQSGEATITVSVDDMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     LVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDANDNPVTGLNPDAPSLSGAAAAGSTASGW
                     TDNGDGTWIAQISLGTTAGELDVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTASEGATVSSWTEKGDGSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKTPTVKTTTELTFTV
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGEHNISASVNGAQKTVTVKF
                     NADASTGQANLQVDTAVQKVANGKDAFTLTANVEDKNGNPVPGSLVTFNLPRGVKPLT
                     GDNVWVKANDEGKAELQVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISSIE
                     VIGNRAVADGKTKQTYKVTVTDANNNLLKDSEVTLTASPENLVLTPNGTATTNEQGQA
                     IFTATTTVAATYTLTAKVEQADGQESTKTAESKFVADDKNAELAATSDVHSLVADGVT
                     TATLTVTLFSANNPVGGTMWVDIEAPEGVTEADYQFLPSKNDHFASGKITRTFSTNKP
                     GTYTFTFNSLTYGGYEMKPVTVTINAVPADTEGAEEK"
     gene            complement(4586..5443)
                     /locus_tag="LSX49_004839"
     CDS             complement(4586..5443)
                     /locus_tag="LSX49_004839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7171114.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLSAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKLPDEEVKL
                     RRHHLVRCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWTINRG
                     LYASFRYEGEWEHYPEWARNLYLMELPARGLARVNGSDIERFYYNENFVEIDSNNIVC
                     EIFIPVRPV"
     gene            5691..6560
                     /locus_tag="LSX49_004840"
     CDS             5691..6560
                     /locus_tag="LSX49_004840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL7171115.1"
                     /translation="MEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLID
                     TAAVYGNEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSG
                     LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
                     NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQV
                     ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
                     EFVRGCLAVKIHD"
     gene            complement(6720..7313)
                     /gene="rclC"
                     /locus_tag="LSX49_004841"
     CDS             complement(6720..7313)
                     /gene="rclC"
                     /locus_tag="LSX49_004841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HBL7171116.1"
                     /translation="MERYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSARDILKQRSNESSSTLKTEY"
     gene            complement(7325..7561)
                     /locus_tag="LSX49_004842"
     CDS             complement(7325..7561)
                     /locus_tag="LSX49_004842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBL7171117.1"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     NAIADMARKYNASSWKVTSMRIDNNSTATAVLYK"
BASE COUNT         2097 a         1683 c         1934 g         1871 t
ORIGIN      
        1 tttacccata aataaaaata taatcccgcg cccaaccacc tgatgagtgg ctacagacac
       61 tggatatatt aggtggcggt gtactttctt acataaaggt atttcctttt ctgtggaaaa
      121 ggaaaccggg aaatccccgg tttttctgac aagcagacgc cattatttgt gtctgcctat
      181 gttcgttaat tcgttcatca ggaaattatc tcaatgtcac gttataaaac agacaataaa
      241 cagccacgat ttcgttattc agttctggcc cgctgcgtgg cgtgggcaaa tatctctgtt
      301 caggttcttt ttccactcgc agtcaccttt acgccagtaa tggcagcacg tgcgcagcat
      361 gcggttcagc cacggttgag catggaaaat actacggtaa ctgctaataa taacgtggag
      421 aaaaatgtcg cgtcgcttgc cgctaatgcc gggacatttt taagcagtca gccagatagc
      481 gatgcgacac gtaactttat taccggaatg gccaccgcta aagctaacca ggaaattcag
      541 gagtggctcg ggaaatacgg tactgcgcgc gtcaaactga atgtcgataa aaatttctcg
      601 ctgaaggact cttcgctgga aatgctttat ccgatttatg atacaccgac aaatatgttg
      661 ttcactcagg gggcaataca tcgtaccgac gatcgtactc agtcaaatat tggttttggc
      721 tggcgtcatt tttcagaaaa tgactggatg gcgggggtga atacttttat cgatcatgat
      781 ttatcccgta gtcatacccg cattggtgtt ggtgcggaat actggcgtga ttatttgaaa
      841 ctgagcgcca atggttatat ccgggcttct ggctggaaaa aatcgccgga tgttgaggat
      901 tatcaggaac gcccggcgaa tggctgggat attcgtgctg agggctattt acctgcctgg
      961 ccgcagcttg gcgcaagcct catgtatgaa cagtattatg gcgatgaagt cgggctgttt
     1021 ggtaaagata aacgccagaa agatccacat gcgattaccg ctgaagtgaa ttacacgcca
     1081 gtgcctcttc tgaccctgag tgccgggcat aagcagggca agagtggtga gaatgacact
     1141 cgctttggcc tggaagttaa ttatcggatt ggcgaacctc tggaaaaaca actcgataca
     1201 gacagcattc gcgagcgtcg aatgctggca ggcagccgct atgacctggt tgagcgtaat
     1261 aacaatatcg ttcttgagta tcgcaaatct gaagtgatcc gtattgctct gcctgagcgt
     1321 attgaaggca agggcggcca gacggtttcc ctggggcttg tggtcagcaa agcaactcac
     1381 ggtctgaaaa atgtgcaatg ggaagcgccg tctttgctgg ccgcaggcgg aaaaattacg
     1441 gggcagggca atcagtggca agtgacgctc ccggcttatc aggcaggcaa agacaattat
     1501 tatgcgattt cagcgattgc ctacgataac aaaggcaatg cctcgaaacg tgtgcagaca
     1561 gaagtggtta ttagcggagc tggtatgagc gccgatcgta cggcgttaac gcttgacggt
     1621 cagagccgta ttcaaatgct tgctaacggt aatgagcaaa agccgctggt gctgtctctg
     1681 cgcgacgccg agggtcagcc agtcacgggc atgaaagatc agatcaagac tgaactaacc
     1741 ttcaaaccgg ctggaaatat tgtgactcgt accctgaagg ccactaaatc acaggcaaag
     1801 ccaacactgg gtgagttcac cgaaactgaa tcaggggtgt atcagtctgt ctttactacc
     1861 ggaacgcagt caggtgaggc aacgattact gttagcgttg atgacatgag caaaactgtc
     1921 actgcagaac tgcgggccac gatgatggat gtggcaaact ccaccctgag cgctaacgag
     1981 ccgtcaggtg atgtggttgc tgatggtcag caagcctaca cgctgacact gacagcggtg
     2041 gactccgagg gtaatccggt gacgggagaa gccagccgcc tgcgacttgt tccgcaagac
     2101 actaatggtg taaccgttgg tgccatttcg gaaataaaac caggggttta cagcgccacg
     2161 gtttcttcga cccgtgccgg gaacgttgtt gtgcgtgcct tcagcgagca gtatcagctg
     2221 ggcacgttac aacaaacgct gaagtttgtt gccgggccgc ttgatgcagc acattcgtcc
     2281 atcaccctga atcctgataa accggtggtt ggcggtacag ttacggcaat ctggacggca
     2341 aaagatgcta atgacaaccc tgtaactggc ctcaatccgg atgcaccgtc attatcgggc
     2401 gcagctgctg ctggttctac ggcatcaggc tggacggata atggcgacgg gacctggatt
     2461 gcgcagattt ctctcggcac tacggcgggt gaattagacg ttatgccgaa gctcaatggg
     2521 caggacgcgg cagcgaatgc ggcaaaagta accgtggtgg ctgatgcatt atcttcaaac
     2581 cagtcgaaag tctctgtcgc agaagatcac gtaaaagccg gtgaaagcac aaccgtaacg
     2641 ctggtggcga aagatgcgca tggcaacgct atcagtggtc tttcgttgtc ggcaagtttg
     2701 acggggaccg cctctgaagg ggcgaccgtt tccagttgga ccgaaaaagg tgacggttcc
     2761 tatgttgcta cgttaactac aggcggaaag acgggcgagc ttcgtgtcat gccgctcttc
     2821 aacggccagc ctgcagccac cgaagccgcg cagctgactg ttattgccgg agagatgtca
     2881 tcagcgaact ctacgcttgt tgcggacaat aaaactccaa cggttaaaac gacgacggaa
     2941 ctcaccttca ccgtgaagga tgcgtacggg aatccggtca ccgggctgaa gccagatgca
     3001 ccagtgttta gtggtgccgc cagcacgggg agtgagcgtc cttcagcagg aaactggaca
     3061 gagaaaggta atggggtcta cgtgtcgacc ttaacgctgg gatctgccgc gggtcagttg
     3121 tctgtgatgc cgcgagtgaa cggccaaaat gccgttgctc agccactggt gctgaatgtt
     3181 gcaggtgacg catctaaggc tgagattcgt gatatgacag tgaaggttaa taaccaactg
     3241 gctaatggac agtctgctaa ccagataacc ctgaccgtcg tggacagcta tggtaacccg
     3301 ttgcaggggc aagaagttac gctgacttta ccgcagggtg tgaccagcaa gacggggaat
     3361 acagtaacaa ccaatgcggc agggaaagtg gacattgagc ttatgtcaac ggttgcggga
     3421 gaacacaata tttccgcttc ggtgaatggt gctcagaaga cggtcacggt gaaattcaac
     3481 gcggatgcca gcaccggtca ggcaaacctg caggtagaca ccgccgttca aaaagtggca
     3541 aacggcaaag atgcctttac gctgacggcg aacgttgagg ataaaaatgg taaccctgtt
     3601 ccagggagcc tggtgacctt taatctgccc cggggtgtca agccgcttac aggcgataat
     3661 gtgtgggtga aagccaacga tgaggggaaa gcggagttgc aggtggtttc cgtgactgcc
     3721 ggaacctatg agatcacggc gtcagcagga aatgaccagc cttcgaatgc gcagtctgta
     3781 acgtttgtgg ccgataagac tacggcgacc atctccagta ttgaggtgat tggcaaccgt
     3841 gcagtggcgg acggcaaaac caaacagacg tataaagtta cggtgactga tgccaataac
     3901 aacctgctga aagatagcga agtgacgctg actgccagcc cggaaaattt agttctgact
     3961 cccaatggga cggcgacaac gaatgagcaa gggcaggcta ttttcaccgc cacgaccact
     4021 gtcgcagcga catatacact cacggcgaaa gtggaacagg ccgacggtca ggaatcgacg
     4081 aaaactgccg aatctaaatt cgtcgcggat gataaaaacg cggagctcgc cgcaacatct
     4141 gatgtgcatt ctctggtggc ggatggggta acgacagcaa cactgacggt aaccctgttc
     4201 tcggcaaaca acccggtagg aggaaccatg tgggtcgaca ttgaggctcc ggaaggggtg
     4261 acagaggcgg attatcagtt cctgccgtcg aaaaatgacc atttcgcgag cgggaaaatc
     4321 acgcgtacat ttagtaccaa caagccaggt acatacacat tcacattcaa ctctttgaca
     4381 tatggagggt atgaaatgaa acccgtgact gtgacaatta acgccgttcc tgcagatact
     4441 gaaggtgctg aggagaaata aaaacgacga tgtaataaat aataatggcg ttgacatgcg
     4501 cagcgccatt atttactgaa tacctaccct ggcaccgatt agacggtggc agggtagggt
     4561 aaatcttatg tgatggagtt acaggctaaa ccgggcgaac ggggataaaa atttcgcaaa
     4621 caatgttatt gctatcaatt tcgacgaagt tttcattgta ataaaatcgc tcaatatcac
     4681 tgccgttcac tctggctaac cccctggcag gtaattccat cagatagagg tttcgcgccc
     4741 attcagggta gtgctcccac tcaccttcat agcggaaaga ggcatacagt cctcggttaa
     4801 ttgtccactc tttcggcatc tctgaatcgg tttgtttgca taccgtaccg gcaaaagttt
     4861 caactgtgag caaatcgacc gattttgttg atggttcgaa cgtggagacg aaatagatat
     4921 ccgtcttaaa attcttcata catctgacta aatgatgacg tcgcagtttg acttcttcat
     4981 ccggtaattt attcgacact tcaatatcat atttaaatga attgccaaaa ataggtgtct
     5041 caggaaagtt gactaatcta cactccgtct tttgctgttg acgtattaaa aaagaaggga
     5101 agatatttgc gagatcccaa taatcacggt ggcggtattc acggggagag cagccgaata
     5161 actttttaaa ttcgcggctg aatgactgct gtgaatcaaa atgcaaagag agtgcaatat
     5221 caagcataga tttcgcggag agccggacaa gaatggcggc acgacaaagc cttcgtttgc
     5281 gaatgtattc tcccaaaggc acatgcatga aatttcggaa cagaagctgg atgttgcgtc
     5341 tgctgtagcc agatttctgt gcgatatctt cgattgaaat agggtgctca agattgcact
     5401 caatccactc caggagctgc tgtagaatct tctgcctgat catcacatac tccgttaatt
     5461 ctttgtcata tcgcacattt tcgttatgtc ctgggcccta agtgtatcaa aaacagcaag
     5521 tcccaaggca aaagcactga tagcgtctgc ttcattgccc caaaaataga gaggtttcag
     5581 tcctacatta ttaatgaatt ttttgcataa gtgatatcaa aatccacata ctaatttgag
     5641 gttacgtttt aacgtagact cattgttcat acctaatgga gggactgaca gtggaatttt
     5701 ccgtattaag taacaatctg aaaatgccga tgatgggatt tggtgttttt caggttaccg
     5761 ataaagacgt gtgcaaacag tcagtgttga atgctatccg cacgggttat cgactcatcg
     5821 acactgcagc ggtatacggt aatgaagatg ccgtcggtga agccgttcgt gaagccatat
     5881 ctgaaggttt atgtacccga gaagagttat ttataacgtc taaattgtgg gtgcaggata
     5941 tgttgaatca ggatattgca gcagcaggta ttgaagcatc attaaaaaaa tcggggctag
     6001 aatacttcga tctctattta ttgcaccagg ccatgcgcga ttattttagt gcgtggcgtg
     6061 cactcgaaga tgcctatgaa gagggcaaat taaaagcgat tggggtttcc aatttctacc
     6121 ctcatgttct ggcgaacttt tgtgaaacgg taagagttaa accgatggtc aaccaggtcg
     6181 agttgcatcc ctattttgcc caaccagagg cgctggcaac catgaagtat tataacgtgc
     6241 agcctgaagc atgggctccg ttaggtggtg gacgacataa accctttgaa aataatctgc
     6301 ttcagagtat tgcagatgcc catcaaaaat cgatttctca ggtcattctg cgttggaata
     6361 ttcaacgggg agtggtcgtt attccgaaat cgacacatca acagcgtatc gaagaaaatt
     6421 ttgctatctg ggatttctca ctgacagaga aagaaatggc gcaaattagt tcgctagatt
     6481 tgggttatgt tggggaatcg gtaaaacatt ttaatcctga gtttgttcgt ggttgtcttg
     6541 ctgtaaaaat acatgattga tattaatcac ttattttacc tgagacgaca aaaatttttt
     6601 aacaggggag tgatattgat cgtcactctg tcatatctcc ggtaatatgg cgtcaggctt
     6661 catcaacaga aagggggcct gacgcctgaa aaagtgaaca acagacagtg ttcggattat
     6721 caatattcag tttttaacgt tgaactggat tcattactgc gttgtttaag aatatcccgt
     6781 gccgaatctg ccattatcat gacagcacct gccagcatca gagtatcttt caataccaga
     6841 cgaccagcac cggataaata agggaaacca tgatgagcat cacccaatgc gggtacccat
     6901 gcctccggag tggtgattaa aaatgagagt gttaccagcg gcgtggtaaa tgccatcagc
     6961 ccacccaata aacctaacca gcgattgaca ggattagcca aaaccagcag agcaataatc
     7021 acctccacga cgccaagacc gttggaaaaa ccataggtat tattagccgt ttgccatgct
     7081 cttgcttctg gtttgtattc gccttcgtga gtcagatact gtttatagtc ttccgggtgt
     7141 tcataaaaga acgacattag tggactgttt gcgacgaatg gtgtaatgct gtctgcctcg
     7201 taagggacaa actttaataa cccaatccac ataaaaacaa tcgcaatgct cagacgaatc
     7261 aatgtcaggc caattttatc tccccgactt aacaggtgca ggtatctttc cattgtaaac
     7321 atccttattt atacaatact gctgttgcgg ttgaattatt atcaattcgc atcgatgtaa
     7381 ctttccagga tgaagcatta tattttctgg ccatatcagc aatggcattc tcaagaactg
     7441 tcggtgatgc tgatactgat gagacgctga tatgtttcag aattatttta tcatctgcat
     7501 tggtggaaaa tgccataacg ccagataata gtgttgcaaa taaaacagat tttttaaaca
     7561 tataaaatac catcaatgaa gtgat
//
LOCUS       DAFGPF010000184         7396 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFGPF010000184 DAFGPF010000000
VERSION     DAFGPF010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7396
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.184"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(339..2009)
                     /gene="betA"
                     /locus_tag="LSX49_004843"
     CDS             complement(339..2009)
                     /gene="betA"
                     /locus_tag="LSX49_004843"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HBL7171118.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVITSKPGVNPLFEA
                     MIEAGMQAGYPRTDDLNGYQQEGFGPMDRTVTPHGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRAAANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFNIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPRIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPGILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGKEALPRSTAGYFVANGMPVRAKK"
     gene            complement(2023..3495)
                     /gene="betB"
                     /locus_tag="LSX49_004844"
     CDS             complement(2023..3495)
                     /gene="betB"
                     /locus_tag="LSX49_004844"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HBL7171119.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTD
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPTKCKAAFEQKVLARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGNVLKGDSFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSILIYESEDEVIRRANDTDYGLAAGIVTADLNLAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            complement(3509..4096)
                     /gene="betI"
                     /locus_tag="LSX49_004845"
     CDS             complement(3509..4096)
                     /gene="betI"
                     /locus_tag="LSX49_004845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308386.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HBL7171120.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAELRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD"
     gene            4225..6258
                     /gene="betT"
                     /locus_tag="LSX49_004846"
     CDS             4225..6258
                     /gene="betT"
                     /locus_tag="LSX49_004846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HBL7171121.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKNLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     gene            7136..>7396
                     /locus_tag="LSX49_004847"
     CDS             7136..>7396
                     /locus_tag="LSX49_004847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7171122.1"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEI"
BASE COUNT         1611 a         1896 c         1967 g         1922 t
ORIGIN      
        1 cgtgtttaaa gctccatgtg gttttggtct gacttatttt tgtactcgtt acaagaaccc
       61 ttttcgtata tgctaaccgt gagcgggaat gaacaggtaa ccatagccag gaacattagc
      121 ggcgtaattc ttaagctgag tggtatttca tctgtagttt atctgtgtat gcatagcaca
      181 ttcatcagcc agattgagca agtcagctta gaatttgctg gcgagattgt cacgatgaag
      241 catgagagtt acctcagtgt tttatataag gattcggtcc tcatagtaga acggtaactc
      301 tcaatctgat aggttcctga gtcagttcac atcacgactc attttttcgc tctcaccggc
      361 atcccatttg ccacaaaata tcccgccgtg ctcctcggca acgcttcctt cccacgaatc
      421 atatccgcta ttttctcgcc aatcataatc gtcgtggcgt tcaaattgcc ggtgataatt
      481 tgcggcataa ttgacgcatc caccacgcgc aggccttcca gcccgtgtac gcggccttcg
      541 ccgtcaacca cagccatctc gtcataaccc attttgcagg taccgcacgg atgaaacgcg
      601 gtttcggcgt ggttacgcac gaactcatcg agctgctcat ccgtctggca ttcgacacca
      661 gggctgattt cgcggccacg gtattgatcc agcgcgggtt gatgcatgat ctcgcgtgtg
      721 atgcgaattg cgtcgcggaa ctcctgccag tcctgctcgt gcgacatgta gttaaacaga
      781 attcccggat gctggtgcgg gtcgcgggat ttaatccgca catgcccacg gcttggcgag
      841 cgcatcgatc cgacatggca ttggaagccg tgctctttca ctgcgttcga gccgttatag
      901 ttaatcgcca ctggcaggaa atggtactga atattcggcc acgcaaattc ctcacggctg
      961 cgaataaatc cgcctgcttc aaagtggttg ctggcaccaa cgccggtgcc gccaaacagc
     1021 cactccgcac cgattctcgg ctgattccac cactgcaggg cagggtagag ggaaaccggt
     1081 tctttgcact cgtattgcag atacatctcc aggtgatcct gaagattttc gccgacgccg
     1141 ggtaattcat gcaccagcgg aatattaaac tccgccagca gttcagcgtt gccgacgccg
     1201 gagcgttgca ggatctgcgg tgaagcaatc gcgcctgcac ataacagcac ttctttattc
     1261 gccgccgcgc gggtcggaat agtgctgtcg ccttccagcc actcgacgcc caccgcgcgt
     1321 ttgccgtcaa aaatgatgtg atcggtcatg gcgtgagtac gaatggtcag gttagggcgc
     1381 gatttggcct gatcgagata gccacgcgcg gtgctggcgc gacggccatg cggcgtgacg
     1441 gtgcgatcca tcgggccaaa accttcttgc tgatagccgt tgagatcgtc cgtgcgtggg
     1501 tagcctgcct gcatgcccgc ttcaatcatc gcttcaaaca gcggattgac gccgggtttg
     1561 gaggtgatga cgctcaccgg gccatcgcca ccgtggtaat cgttctcgcc cacatcgcga
     1621 gtctcggcct tgcggtagta gggcaggcag tcgagataac tccagttctc cagaccaggt
     1681 tcttgtgccc agttatcgag atccagcgca ttgccacgga tgtagcacat accgttgatc
     1741 agcgatgaac cgcccagacc tttgccgcgt ccgcactcca tgcggcggtt gttcataaac
     1801 ggttcgggtt ccgtctcata ggcccagttg tagcgtttgc cctgtagcgg gaacgccagc
     1861 gcggcgggca tctgggtgcg gaagtcaaag cgatagtccg ggccgcctgc ttcaagcagc
     1921 agcacggttg tgttcggatc ttcagtcaga cgggtagcga gaacgttgcc ggctgagccg
     1981 gcaccaataa tgatgtagtc aaattgcaaa taaacctcct ggttagaata tggactggaa
     2041 tttagccatc tcaacctgga tggacttcac ctgggtgtaa ctctggagcg tcatcacgcc
     2101 gttctcgcga ccaatgccgg agtgtttgta gccgccaacg ggcatctctg ccggggattc
     2161 gccccaggtg ttgatccagc aaatacccgc ttccagctga tgaatgacgc gatgcgcgag
     2221 gttcaggtcc gccgtcacga tacccgccgc cagaccgtag tcggtatcgt tagcgcggcg
     2281 aatgacttcg tcttccgact cgtagatcag aatggacatc actggcccga aaatctcttc
     2341 tcgcacaatg gtcatatcgt cgctgcaatc ggtgaacacg gtcggtgcaa cccatgcgcc
     2401 gttatcgaag ctatccccct tcagtacatt gccgccgcac agtacgcgcg cgccttcctc
     2461 tttgcctttg gcgatatagc gcagcacgtt atcgcgatgc gggaagctga ccagcgggcc
     2521 gaagttagtt tgcggatcga aaacgtcgcc cgcgcgaatg cgctcaacgc gcgccagaac
     2581 cttttgttca aatgcggctt tgcatttcgt cggaacgaag acgcgagtgc cgttggtaca
     2641 cacctgaccg gagctgaaga aattcgccat catggcgata tcggcggcga gatcgagatc
     2701 cgcatcgtcg aaaacgatca gcggtgattt accgcccagc tccatggtca cttctttcag
     2761 ggaggaagct gccgagttag ccatcacttt tttgccgctg gcgacaccgc cggtaaatga
     2821 cactttggca atgcccggat gatcggtcag atattgtccg gtctccgcgc ccacgcccgg
     2881 caacacgtta aatacgccgt ccggcaggcc cgcttcgctg taaatttcgg ccagctttaa
     2941 cgcggtaagc ggggtgactt cgctcggttt gaaaatcatt gcattgcctg ccgccagcgc
     3001 tggggcggat ttccacaaag caatctggat cgggtagttc catgcgccaa tccccgccac
     3061 cacacccagc ggttcgcggc gggtataaac aaatgacgtc tcacgcaacg ggatctggct
     3121 gccttccagc gccgggatca gcccggcata gtactccagc acgtccgcac cggtaacgat
     3181 atcgacggtt gaggtttccg aatatgcttt tccggtgtca agggtttcca gttttgcgag
     3241 ttcgtcattg cgttcacgca gaatatcaac ggcccgacgc agaatacgcg agcgctccat
     3301 agcggtcatc gccgcccaga ttttttgccc ttgttgggca ctcttcacgg cgcgatcgac
     3361 atcctcacgc ccggcggcct gcacggtcgc cagcacgtta ccgttggccg ggttaatggt
     3421 ctcgaaggtg cgaccgctgg tggcggaggt ataaccacca tgtatataaa gctgctgttc
     3481 tgccattcgg gacatcacgt ctcctcggtt aatcggtggg taaatgctga gtaataaagt
     3541 gacgggtcag cgagtgtgcg agaggtttat ccagcggttt gccgctcagt gccgcgcgca
     3601 gccataatcc gtcaattagc gcggcaaggc cgtagcccgc ttcctgtgcc tgttggcgcg
     3661 gtaactcgcg gcgaaattcg ctcaccagat tcgacaataa gcggcggcta ctgacctgct
     3721 gcaaacggta aagcatcggc tgatgcatac tgctggccca gaaggccagc caggctttca
     3781 tcgccgcact gctcacctgg gtttcatcga agtttccgcc aacaatcgcc tgtaatcgca
     3841 gctctgcact gccctgcgga agtgcatgta atcgattcaa aaccgcgtca cgcagctgac
     3901 tggtgatatc gcgcatggtt gcttccagca gaccattttt gtccctgaaa tagtggctga
     3961 tgatccccgt agaaacgcct gcacggcggg cgatctgcgc gatcgttgca tcgtgcatgc
     4021 ccacttcatt tattgcttcc agcgtggcgt cgatcagttg tctgcgccgg atcgactgca
     4081 ttcccaattt gggcattttc gccactccat tcatcagcgt tgtttatcta ttaaagcggt
     4141 tattgattgg acgttcaata taaaatgtgt cttaattgtt actaatttga ttttaaatgg
     4201 taacaataac agtggggata ctggatgaca gacctttcac acagcaggga aaaggacaaa
     4261 atcaatccgg tggtgtttta cacttccgcc ggactgattt tgttgttttc cctgacaacg
     4321 atcctgtttc gcgacttctc ggccctgtgg attggccgca cgctggactg ggtttctaaa
     4381 accttcggtt ggtactatct gctggcggca acgctctata ttgtctttgt ggtctgtatc
     4441 gcttgttcgc gttttggttc ggtgaagctc gggccagaac aatcaaaacc ggaattcagt
     4501 ttgctgagtt gggcggcgat gctgtttgct gccgggatcg gtatcgacct gatgttcttc
     4561 tccgtagccg aaccggtaac gcagtatatg cagccgccgg aaggcgcggg acagacgatt
     4621 gaggccgcgc gtcaggcgat ggtctggacg ctgtttcact acggcttaac cggctggtcg
     4681 atgtatgcgc tgatgggcat ggcgctcgga tactttagct atcgttataa tttgccgctc
     4741 accatccgct cggcgctgta cccgatcttc ggtaaacgga ttaacgggcc gataggtcac
     4801 tcagtggata ttgctgcggt gatcggcacc atcttcggta ttgccactac gctcggtatc
     4861 ggtgtggtgc agcttaacta tggcttgagc gtgctgtttg atattcccga ttcgatggcg
     4921 gcgaaagcgg cactgatcgc cttgtcggtg atcatcgcca ctatctcggt gacatccggt
     4981 gtcgataagg gcattcgcgt gttatcggaa ctcaacgttg cgctggcgct gggattgatt
     5041 ctgttcgtgt tgtttatggg cgacacctcg ttcctgctta atgcactggt gctgaacgtt
     5101 ggcgactatg tgaatcgctt tatgggcatg acgctcaata gttttgcctt cgaccgtccg
     5161 gttgagtgga tgaataactg gacgctcttc ttctgggcat ggtgggtggc atggtcgccg
     5221 tttgtcggct tgttcctggc gcgtatctcg cgtgggcgta ccattcgcca gttcgtgctg
     5281 ggcacgttga ttattccgtt taccttcacg ctgttatggc tctcggtatt cggcaatagc
     5341 gcgctgtatg aaatcatcca cggcggcgcg gcatttgccg aggaagcgat ggtccatccg
     5401 gagcgcggct tctacagcct gctggcgcag tatccggcgt ttacctttag cgcctccgtc
     5461 gccaccatta ctggcctgct attttatgtg acctcggcgg actccggtgc gctggtgctg
     5521 gggaatttca cctcgcagct taaagatatc aacagcgacg cacccggctg gctgcgcgtc
     5581 ttctggtcgg tggcgattgg cctgctgacg ctaggcatgc tgatgaccaa cgggatatcc
     5641 gcgctgcaaa acaccacggt gattatgggc ctgccgttca gctttgtgat cttcttcgtg
     5701 atggcggggt tgtataaatc tctgaaggta gaagattacc gccgtgaaag tgccaaccgc
     5761 gataccgcac cgcgaccgct ggggcttcag gatcgcctga gctggaaaaa acgtctctcg
     5821 cgcctgatga attatccggg cacgcgttac actaaacaga tgatggagac ggtctgttat
     5881 ccggcaatgg aagaagtggc gcaggaactg cggttgcgcg gcgcgtacgt ggagctaaaa
     5941 aacctgccgc cggaagaggg acaacagttg gggcatctgg atttgttggt gcatatgggc
     6001 gaagagcaaa actttgtcta tcagatttgg ccacagcaat attcggtgcc gggctttacc
     6061 taccgcgcac gtagcgggaa atcgacctac taccggctgg aaaccttcct gttagaaggc
     6121 agccagggca acgacctgat ggactacagc aaagagcagg tgatcaccga tattctcgac
     6181 cagtacgagc ggcaccttaa ctttatccat ctccatcgtg aagcgccggg ccatagcgtg
     6241 atgttcccgg acgcgtgatt gttattgcat aaaaccgcgc catgtctgca tatggcgcgg
     6301 tttctcttac ctcttgatac gttatatctg tgtacagtta agcccttagt atcgattgat
     6361 gattgccagg caacagataa taaaaaagaa aagaactatt gaagcccaaa acctacgctt
     6421 ggactgttgt gaatgttcaa taagcttagt cttatttaat gtaaatattg gtgctaattt
     6481 gaaatgacgc tttattcatg ggaaacgcgt agcgcaaatc aaccaaaatc aatgtaaccg
     6541 tttgttgttt aaggtttaat tgtctgtgtc tgatatttta ttgattgttt taaatattgt
     6601 ttttattgtc attgttataa tgttggctat ctattgctga atggattcag tcttaaaaag
     6661 caggttgtta agggattagc atagagtaat gacgtgtatg cataaccaac atctttactc
     6721 attatgtcat tgaatgttga cgctatgtgt ttatgaggtt gaggtatttt cagttgatct
     6781 ggattgttaa attcatataa tgcgccttta ctcatgaatg gacgtcaata cgtagtggga
     6841 aattataaat atcgaaatag tccaactact tctttattac caaaaatgag tatctgaatt
     6901 ttaatattgc attcttgcgt gattatctcc tgagtttgac ttgtgattac ctttttaagg
     6961 tatttagcgt aactgttttt gagcgagcat cagaggtaaa gataatcttc ttgatagtga
     7021 tgtgggatgt tatacgtatg gcatcgctaa tgtttatggt taccccttat gtgtgctcag
     7081 gaatccacag gtaatcactc atactgaaca gcgataaaag ataaaaggtg tgttcatgaa
     7141 ttcatgtgat tttcgtgttt ttctgcaaga gttcggtaca acggttcatt tgtcattgcc
     7201 tggtagcgta tccgagaaag aacgactgct actcaagctg ctgatgcagg gaatgtctgt
     7261 aacagaaata tcacagtaca gaaatcgcag tgcaaagacc atttcacatc aaaagaaaca
     7321 gctctttgag aaactgggga ttcagagcga tattactttc tggcgggata ttttctttca
     7381 gtacaatccg gagatc
//
LOCUS       DAFGPF010000185         7379 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFGPF010000185 DAFGPF010000000
VERSION     DAFGPF010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7379
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.185"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(307..549)
                     /locus_tag="LSX49_004848"
     CDS             complement(307..549)
                     /locus_tag="LSX49_004848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171123.1"
                     /translation="MKNIISVTVLSALFMFNAQAADTMDKTHEVKGSMSSAHDKMCKD
                     GMCKNAMDKEKMEKEHMSKTDGMKNDHMGKKDNMSQ"
     gene            complement(604..1347)
                     /locus_tag="LSX49_004849"
                     /pseudo
     CDS             complement(604..1347)
                     /locus_tag="LSX49_004849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741110.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
     gene            complement(1347..1945)
                     /locus_tag="LSX49_004850"
                     /pseudo
     CDS             complement(1347..1945)
                     /locus_tag="LSX49_004850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182766.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b/b6 domain-containing protein"
     gene            2086..2805
                     /locus_tag="LSX49_004851"
     CDS             2086..2805
                     /locus_tag="LSX49_004851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL7171124.1"
                     /translation="MNNVKKILLMEDDYDIAALLRLNLQDEGYQIVHEADGARARLLL
                     DKQTWDAVILDLMLPNVNGLEICRYIRQMTRYLPVIIISARTSETHRVLGLEMGADDY
                     LPKPFSIPELIARIKALFRRQEAMGQNILLAGGLICCHDLCINPFSREVHLHNKQVDL
                     TPREFDLLLWFARHPGEVFSRLSLLDNVWGYQHEGYEHTVNTHINRLRAKIEQDAAEP
                     KMIQTVWGKGYRFSVDNAGMR"
     gene            2806..4278
                     /locus_tag="LSX49_004852"
     CDS             2806..4278
                     /locus_tag="LSX49_004852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL7171125.1"
                     /translation="MNCSLTLSQRLSLVFTVVLLFCAAVTCGVHIYSSNLYGNAMVQR
                     LSAGLAQQIVITEPLLDNRGQVNHRTLKSLFERLMTLNPSVELYIVSPEGRLLVEAAP
                     PGHIKRRYINIAPLKKFLSGAVWPVYGDDPRSVNKKKVFSTAPLYLRDDLKGYLYIIL
                     QGEELNALTDAAWTKALWNALYWSLFLVVICGLLSGMLVWYWVTRPIQQLTENVSGIE
                     QDSISAIKQLAIQRPATPPSNEVEILHNAFIELARKISCQWDQLSESDQQRREFIANI
                     SHDLRTPLTSLLGYLETLSMKSDSLSSEDCHKYLTTALRQGHKVRHLSCQLFELARLE
                     HGAIKPQLEQFSVCELIQDVAQKFELSIETRRLQLRIMMSHSLPLIRADISMIERVIT
                     NLLDNAVRHTPPEGSIRLKVWQEDNRLHVEVADSGPGLTEDMRTHLFRRASVLCHEPS
                     EEPRGGLGLLIVRRMLVLHGGDIRLTDSTTGACFRFFLPL"
     gene            complement(4358..5532)
                     /locus_tag="LSX49_004853"
                     /pseudo
     CDS             complement(4358..5532)
                     /locus_tag="LSX49_004853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558235.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(5606..5857)
                     /locus_tag="LSX49_004854"
                     /pseudo
     CDS             complement(5606..5857)
                     /locus_tag="LSX49_004854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743492.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(6508..>7379)
                     /locus_tag="LSX49_004855"
     CDS             complement(6508..>7379)
                     /locus_tag="LSX49_004855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171126.1"
                     /translation="NLIKSKESRAYAYENAHDYAVDLISEEIRSILQISENLKKSLSK
                     NSLSHWPIFHYAENGCKNFLLTGKKQKDLSVEHLRNILSADSLEEIQHAIEHASLGKK
                     EYLSQDGEEDKKLMQLCSLEITRRSLRYHSHIDNVSLKQGTLLLDAYNFVYLCIQPLC
                     DSVRLHEKADFLFLRGTLDDNNYNLLIEDEYGGFYKIKMPAKASNIISFSFGVENGNG
                     VIIGKKNNLVNTDYISFVPLLVEKISTPKVLKWIGEIKTTYAQKITTDIVANLSRIGL
                     DQHEWLRIKSKDI"
BASE COUNT         2107 a         1593 c         1526 g         2153 t
ORIGIN      
        1 aaatacattt aattagcgcg gtaataattt tcaggttatt aaatttataa catggagaat
       61 tttaacgaaa actgactgaa acaaatcaga ccagttaacc agtcagtcgg ttttatgatt
      121 tcactcacta tactttgttt cataaggatt tcaggatctg ccagactgcg cagaaatgat
      181 gcttacgaat acacagtaaa ggcaatgtca tttccgatac agagcctgac attgccataa
      241 tgagctattt atctgaaaaa cgacagaata tgatgtttta tcgtaacgta attttaagtt
      301 ctcaacttat tgagacatat tgtctttttt acccatgtgg tcatttttca tcccatccgt
      361 tttgctcatg tgttctttct ccattttctc tttatccatt gcatttttgc acataccatc
      421 cttgcacatt ttatcatgcg cgctggacat gctgcctttt acttcatgtg ttttatccat
      481 tgtgtctgca gcctgagcat tgaacatgaa cagcgcggat agtacagtta cagaaataat
      541 atttttcatg gttcctcctc atttttaaca attgtatcaa caaccaccaa accagttata
      601 accctagtct tcccagtacc cccccggaaa atgattagtg acctctataa cctgaacatg
      661 cttggggttt ttatatccca gcttagtagg gatacgtatc tttatgggat agccatattc
      721 ttttggcaat accctgttat tccatgtcaa tgtcagcaat gtttgtgaat gtagtgctgt
      781 cgccatatca atactggtgt agtaaccatc gacgcaacga aaactgacgt attttgcccg
      841 catatcggca ccaatcagcg tcaggaaatg ccggaatggt atccctcccc attttcctat
      901 tgcactccat ccttcaacac agatatgacg ggttatctga ctcacatgct gcatgttata
      961 caattcagac aaaaaccagt tacggttatc acgtaccagc ccccgtattt ccaatttata
     1021 atcctagcca tcaattactg ggatctcttc ttctccatag aaggcattaa aagggaatgg
     1081 agtggtaatg tcctctggaa gatattctgg tgccacactg tttttgctga acagaaaact
     1141 ttgaatccgg tcattaaatc tggatatacg gaacaatgct ttttcaatat catcattatt
     1201 gcttatatca cagccagtca gcatcataat tcccccaagc gtcagtccct gttggagtaa
     1261 acgacgtctg tccggcgcaa ggattttttc tgcatctttc accacgtaat gggcatcact
     1321 gtcagacaaa aaatgttttt tcttcattag tgaccccgta tcatagataa caatgcacgc
     1381 ggaaccaata acaccataac caggtgaata ataataaaca gtaccataat gttcatgcac
     1441 agaaagtgga tataacgcac tgtatcataa ccaccgaata gtatagtcag aagggaaaac
     1501 tgaacgggtt tccataaaac cagaccagac aatagcagag cagcgccatc taaaataaca
     1561 gaatataggc gactttttgc accatattgt attcctgcat attcgtatga tgcagctttc
     1621 catacagtgc ctgcgtaagg gattctttca gtgaggtcca tgacagcggg aaaaacttgc
     1681 tccggaaacg tccgctacaa attcccagag taagatagat cctggcatta atcagcagaa
     1741 tccacatcag ggcgaagtgc cacagtaacg caccaccaag ccagccaccg agagttaatg
     1801 ctgccggata gttaaaagaa aacaaaggag aagcattata aatgcgccat ccactacata
     1861 tcatgcctgc gacagtaaca gcattaatcc ggtggcaaca gcgtaaccac agaggatgta
     1921 tttgttttaa cggtaatggc tgcattatgt gatctctgtc tgtaaactaa gtatattatg
     1981 gaaaggaatg ttcatcacat cctcacaaga gtttaaaaaa aatgtgataa ttcatcgtca
     2041 aatgctgggg taaaattcag ataaagaata tgtggataac ttttgatgaa taacgtaaaa
     2101 aaaatactgc tgatggaaga tgattatgat attgcagctc tgttgcggct taatctgcag
     2161 gatgaagggt atcagatagt tcatgaagcg gatggcgcca gagctcgttt attactagac
     2221 aagcagacct gggatgccgt aatacttgat cttatgctgc ctaatgttaa tgggctggag
     2281 atttgccgtt atatccgtca gatgacccgt tatctgcctg tgattatcat cagtgcccgt
     2341 accagcgaaa cccaccgcgt cctgggactg gaaatggggg ctgatgacta tctaccgaaa
     2401 cccttttcca ttccggagct gattgcccgc atcaaagcgt tgtttcgtcg tcaggaagcc
     2461 atggggcaaa atattctcct ggcaggtgga ctgatttgct gtcacgatct gtgcatcaat
     2521 ccattttcac gtgaagttca tttgcataat aaacaggttg atcttacccc acgcgagttt
     2581 gatctgctgc tctggtttgc acgtcatcct ggcgaagttt tttcccgtct ttcactgctg
     2641 gataatgtct gggggtatca gcatgaagga tatgagcata cagtcaacac gcatatcaac
     2701 cgtcttcgtg ccaaaattga acaggatgca gcagagccaa agatgatcca gaccgtctgg
     2761 ggaaaagggt ataggttttc agttgacaat gcaggaatgc gataaatgaa ttgtagcctg
     2821 acattaagcc agaggttaag cctagtattt acagtcgttt tgctgttttg cgcagcagtg
     2881 acatgtggcg ttcatattta cagcagtaat ctgtatggca atgcaatggt acagcgttta
     2941 tctgcagggc tggcgcaaca gattgtcatc acggagcctc tgctggataa tcgtgggcag
     3001 gtgaatcacc ggacattaaa gagtctgttt gagcgtctga tgacgcttaa tcccagtgtg
     3061 gagctgtata ttgtctcgcc ggaaggtcgg ctgcttgtgg aggccgcccc tccaggtcat
     3121 atcaaacgtc ggtatatcaa tatagcgccc ttgaaaaaat ttctctccgg tgctgtctgg
     3181 cccgtatatg gtgatgatcc ccgaagtgta aataagaaaa aagttttcag taccgcaccg
     3241 ctttacctga gggatgatct gaaaggatat ctgtatatta ttttacaggg agaggaactt
     3301 aatgctctta ctgatgcagc ctggacaaag gcactatgga atgcactgta ctggtcgctg
     3361 tttctggtag tgatatgtgg tctgctgtcg ggtatgctgg tctggtactg ggtaacccgt
     3421 cccatacagc aactaactga aaatgtcagc gggatagagc aggacagtat tagtgccatt
     3481 aaacaactgg caattcagcg ccctgccacc ccccctagca acgaggtcga gatattacac
     3541 aatgccttca ttgaactggc ccgtaaaata tcctgtcagt gggatcaact ttcagaaagt
     3601 gatcaacagc gccgtgaatt tattgccaat atctcccatg atttacggac gccattaaca
     3661 tcacttctgg gatatctgga aaccctgtca atgaagtcgg attcgctatc atcagaggac
     3721 tgtcataaat atctgacaac agctctccgg cagggacaca aggtgaggca tctatcctgt
     3781 cagctttttg agctggcacg tcttgagcat ggtgctataa aacctcaact ggagcaattt
     3841 tctgtctgtg aacttattca ggatgtagct caaaaatttg agctcagcat agaaacccgt
     3901 cgattgcaac taagaattat gatgtcacat tccctgcctc ttatcagggc agatatttca
     3961 atgatagagc gtgtgataac aaatttactg gataatgctg tacgccacac acctccggaa
     4021 ggctcgatca ggctgaaagt ctggcaggaa gataatcggt tgcacgtcga agtggctgac
     4081 agcggccctg gactaactga agatatgcga actcatcttt tccggcgggc atcagtgtta
     4141 tgtcatgaac cgtcagaaga gccccgggga ggactgggat tgctgattgt acgcaggatg
     4201 ctggtactac acggtggtga tatcaggttg actgattcaa cgactggagc ctgctttcgt
     4261 ttttttcttc cattataaca tcaggcggca tattttgggg tggttatgtg tatctgcctt
     4321 tgtaaaaggg atacaagttc tgtagtggag cacaaaatca ggacaccggg ataacctgtt
     4381 tccacttttc ttcatgtaag caaggcggta aaccatcgtt gttcgtgtga ggtcgataaa
     4441 cgttataata taacaaccat taatccactg gtttatatcg cgtaccgcat ggctaaaatc
     4501 accataacca cctttcggaa gccattcact tttcaggctg cgaaagactc tttccatcgg
     4561 cgaattatcc aggccattcc ctctgcaact catactttgc attaccccat aacgccagag
     4621 taactttctg tatttattgc ttttatactg aacaccttga tctgaatgaa acagcaggcg
     4681 gccatcacgc ggtcgagttt ccagtccgtt acgcaaagcc ctacacacca actcagcatc
     4741 agcggttaat gagagggctg aaccgataat ccgccgtgaa tataaatcaa caacgagcgc
     4801 gagctaacac catttgtcct gcaggcgaat aaaactgatg tcgccgcacc agacgcagtt
     4861 tggtgcggcg gggtgaaatt gccggttcag taaatttggc aatggcggac ttttgtcttc
     4921 gtttacccgg ttgtgatgtt taaccggctg tcgacttgtc agccctcatt cccgcatcag
     4981 tcgtcatgcc agccaccggc ctgcatcaac gccactctgg cgcaacatct gactgattgc
     5041 ccggctaccc ggctgcgcca cgactgagag catggaaagc cctcacccgg cttcgtaatt
     5101 caattctttg cacattaaca ggacgcttca cctgcgcgta ataaacgcta cggttaatac
     5161 cgaataaatg acaaataacc cacactggcc actttgcttt cagctgtgtg attagcgcga
     5221 cagcttcccg gggatttcgc tcatcagcac ggcagcctgc tttagtattt ctttttccat
     5281 ctcaacgcgc tttatctgcg ctttaagctg ctgaatttcg cgttgttcag gggtaatagc
     5341 attaccagct ggctcaatac cctgaagttc ctgcttatac aaccgtatcc atttacgcaa
     5401 atggtcaggg ttgagctcga gtgcctgcgc gacttctctg acatcacgct ggtatttaac
     5461 caccacctgc tcgaaagctt caagcttgaa ctccggggaa aaggtacgtt tagtccgacg
     5521 agttttgatc atgcatcacc tcattttcac tgttttaaca ttaacaggat ttcgaggtgt
     5581 cctgaattac cgatccacta caaagtacga caggtactgt ggaggtactc ccgtaaagac
     5641 ggccatcaag ctcccgctcc gacatacctg cgggcagagg ccatgaaaag ccagctttgc
     5701 gaaagcgcac gaacatacca caagctgttg attttggtac gcccaggcga cgcccgacca
     5761 caacctgggg taaatgttct tcaaagtgaa gacgtaaagc ttcagtgatc caagtccggt
     5821 gtttcatacg atagtgtcca ttaaaaatga tggacattat ttttgtaaaa ccggaggaaa
     5881 cagaccagac ggtttaaatg agccggttac atgtaatcca tactcatcca aggtttaatt
     5941 ctgacacaat aagaaaatat ggaaagtctc gctctagaga tggggagagg gatattgaag
     6001 tgtatgatat tccaagaact gccggagata tcctcgtaaa tggattttcc agtgcaaact
     6061 gataacaaat tcgaagtcat tatctgcaac aagattgatt gatgtagggg atatgttaga
     6121 gcattataat gctcaaggat ttggcgtgat gacatctgcg ccaattgatg cgacactata
     6181 tgataaactg gatgctattt gcagtaagtg taaaatagaa caaataaatt tttcagtatt
     6241 agagtcagaa cgcgcactat attatgacga tatattaaga tgccgttact ttggtaaata
     6301 acataaaatt aatcaatatg gtaatatatc agttgtaatt gatcgaaaca aagcacataa
     6361 atgccatctt agaaagatgg tgttttttaa gcatataaaa tatattttct ataagatata
     6421 gggcaaacta aatttcttga cttctatgat ggactaacta gatatacatg ccgccagttt
     6481 ttataaaacg acggcatata taatcattta tatatctttt gattttattc gtaaccactc
     6541 atgttgatct aaacctattc ttgacagatt agcaacaata tcagttgtta ttttttgcgc
     6601 gtacgttgtt tttatttccc cgatccattt caatactttt ggagtagata ttttttcaac
     6661 gagtaaagga acgaatgaga tatagtcagt attaactaga ttgttctttt tccctatgat
     6721 gacaccgttt ccattttcga ctccaaatga aaatgaaata atattagaag cttttgccgg
     6781 cattttaatt ttataaaaac cgccatattc atcttcgatt aacaaattgt aattattatc
     6841 gtccagtgtt cccctgagga ataaaaaatc ggctttttca tgcaatctga cgctatcaca
     6901 taatggttgt atgcatagat agacaaaatt atatgcatct aaaagtaaag ttccttgttt
     6961 taaggacaca ttatctatat gagaatgata tcttaaactc ctgcgcgtga tttccagaga
     7021 gcataattgc attaactttt tatcttcttc accatcttgg cttaagtatt cctttttacc
     7081 taaagatgcg tgttcaatag cgtgttgaat ttcttctaaa gaatcagcag agagtatatt
     7141 ccttagatgt tctactgata agtctttttg tttttttcca gttaatagaa aattcttaca
     7201 accattttct gcatagtgaa aaataggcca atgggataag gagtttttgc ttagagattt
     7261 ctttaagttt tcacttattt gcaatattga tcttatttct tcagaaatta aatctactgc
     7321 ataatcatga gcattttcat aagcatatgc ccttgactcc ttggatttta ttaaattta
//
LOCUS       DAFGPF010000186         7134 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFGPF010000186 DAFGPF010000000
VERSION     DAFGPF010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7134
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.186"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            93..1208
                     /locus_tag="LSX49_004856"
     CDS             93..1208
                     /locus_tag="LSX49_004856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HBL7171127.1"
                     /translation="MKRKVLAMLVPALLVAGAANAAEIYNKNGNKVDFYGKMVGERIW
                     SNTDDNNSENEDTSYARFGVKGETQITSELTGFGQFEYNLDASKPEGENQEKTRLTFA
                     GLKYNELGSFDYGRNYGVAYDAAAYTDMLVEWGGDSWASADNFMNGRTNGVATYRNSD
                     FFGLVDGLDFAIQYQGKNSNRSTKKQNGDGYALSVDYNINGFGIVGAYSKSDRTNDQV
                     ADGNGSNAELWSLAAKYDANNVYAAVMYGETRNMTPGSIDTGVADQEGNTIMRDQLIN
                     ETQNFEAVVQYQFDFGLRPSLGYVYSKGKDIKGVPGHRYVDADRVNYIEVGTWYYFNK
                     NMNVYTAYKFNMLDKDDAAITGAAADDQFAVGIVYQF"
     gene            1801..2652
                     /gene="hchA"
                     /locus_tag="LSX49_004857"
     CDS             1801..2652
                     /gene="hchA"
                     /locus_tag="LSX49_004857"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HBL7171128.1"
                     /translation="MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKP
                     YRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT
                     KFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIG
                     LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHSDNPLNGYSICAFPDAADKQTP
                     DIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQE
                     MLAAYAS"
     gene            complement(2760..4118)
                     /gene="hprS"
                     /locus_tag="LSX49_004858"
     CDS             complement(2760..4118)
                     /gene="hprS"
                     /locus_tag="LSX49_004858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HprS"
                     /protein_id="HBL7171129.1"
                     /translation="MKRLSITVRLTLLFIFLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDGINKIVNRTNVSDDMLN
                     NIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVVIILCSLLSPLLIRTGLREIKKLSGVTEALNYNDSRVPVEVNALPRELKPL
                     GQALNKMHHALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICF
                     KVKCNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTK
                     INEPEKLFRRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQ
                     RN"
     gene            complement(4118..4789)
                     /gene="hprR"
                     /locus_tag="LSX49_004859"
     CDS             complement(4118..4789)
                     /gene="hprR"
                     /locus_tag="LSX49_004859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HBL7171130.1"
                     /translation="MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDD
                     YALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPF
                     SFSELLARVRAQLRQHHALNSTLEISGLKMDSVSQSVSRDNISITLTRKEFQLLWLLA
                     SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSF
                     VAVKK"
     gene            4922..5335
                     /gene="hiuH"
                     /locus_tag="LSX49_004860"
     CDS             4922..5335
                     /gene="hiuH"
                     /locus_tag="LSX49_004860"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HBL7171131.1"
                     /translation="MLKRYLVLSVATAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            5444..6448
                     /gene="msrP"
                     /locus_tag="LSX49_004861"
     CDS             5444..6448
                     /gene="msrP"
                     /locus_tag="LSX49_004861"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HBL7171132.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAAFSLPHAAHA
                     DLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            6449..7084
                     /gene="msrQ"
                     /locus_tag="LSX49_004862"
     CDS             6449..7084
                     /gene="msrQ"
                     /locus_tag="LSX49_004862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HBL7171133.1"
                     /translation="MRLTAKQVIWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLAALLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQSMQRKLGKHWQQLHNFVYLVAIL
                     TPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL"
BASE COUNT         1993 a         1667 c         1514 g         1960 t
ORIGIN      
        1 gaacttcata gaatagtatc caaatgtgct ttttttggat aacagcactt attgatatat
       61 tcatgaagat tataatcaca agggaataca taatgaaaag aaaagttctg gcaatgctgg
      121 tcccggcgtt attagttgct ggcgcagcaa atgcggctga aatttataat aaaaatggca
      181 ataaagttga tttttacggc aagatggttg gcgaacgcat ctggtcaaat actgatgata
      241 ataacagcga aaacgaagat acctcctatg ctcgtttcgg tgttaaaggt gaaacccaaa
      301 tcaccagcga actgactggt ttcggtcagt ttgaatacaa cctcgacgcc agcaagcctg
      361 aaggtgaaaa ccaagaaaaa acccgtttaa ccttcgccgg tttgaaatat aacgagttag
      421 gatcatttga ctatggccgt aactacggtg ttgcttatga tgccgcagct tataccgata
      481 tgttagttga atggggtggc gattcctggg cttccgctga caacttcatg aacggtcgta
      541 ccaacggtgt tgcaacctac cgtaactctg atttctttgg cctggttgat ggtcttgatt
      601 ttgcgattca gtaccaaggc aaaaacagca accgtagcac taagaaacaa aatggtgacg
      661 gctatgcgtt gtctgtagac tataacatca atggttttgg tatcgttggt gcatatagca
      721 aatctgatcg caccaacgat caagttgccg atggaaacgg ttcaaatgct gaactgtggt
      781 cattggctgc aaagtatgac gcgaacaatg tctacgcagc tgtaatgtac ggtgaaactc
      841 gtaatatgac tccgggttct attgatacag gtgttgccga tcaagaaggc aatacaataa
      901 tgcgtgatca acttatcaat gaaacccaga actttgaagc ggttgttcag taccaattcg
      961 actttggtct gcgtccgtcc ttaggttatg tgtactctaa aggtaaagat atcaaaggtg
     1021 tacctggaca tagatatgtt gacgctgacc gtgtgaacta cattgaagtt ggtacctggt
     1081 actacttcaa taagaacatg aacgtttata ctgcatacaa attcaacatg ctggataaag
     1141 atgacgccgc cattactggc gcagcagctg atgaccagtt tgcagttggt atcgtctacc
     1201 agttctaatc agccaacgcg ccgaggcgtg ttactgtaaa acataacacc agcctgagtt
     1261 cgtccctcat cgaactcagg cttttttatt ggcatttcat ctccatctgc ggcacacgca
     1321 attgccaaag catatcgata cagcacatta ccccgcccct cctggctcaa taaaatctac
     1381 cagcgtctct tccagccaac acccaaatgc atttctttat gaattaatcc gcaacaaaac
     1441 cgcttcccat atagaaatat ttgcaaaaat agtgcatgaa aaaaactttt tccctaccaa
     1501 tccgggatat aaatattcat cagtaccaca acattccaca gcactaaatc tctccccatc
     1561 gcccccaaac ctctgataat ggtctaaaat cattgaggcc acttgcgacg acgttactca
     1621 ataaggaaag tttggcgtga ataatattca acaccagtgc agcatcatca ttacatactt
     1681 atgcccgcca actaccgctt tcgatatatt gactcaattt ttcagcctgg ttaaaaatag
     1741 cgaccagctc agtcgcaaat atagtgacta ccctaactaa gcaacaataa ggaatacact
     1801 atgactgttc aaacaagtaa aaacccgcag gtcgatattg ctgaagataa tgcgttcttc
     1861 ccttcagaat attcgcttag ccaatatacg agtcccgtct ctgatcttga tggcgtggac
     1921 tatccaaaac cgtatcgcgg taaacataaa attctggtga tcgccgcgga cgaacgttat
     1981 ttgccgaccg ataacggaaa actgttctcg accggtaacc atccgattga aacgttgctg
     2041 ccgttgtatc atctccatgc tgcaggtttc gaattcgaag tggcgaccat ttccggtctg
     2101 atgaccaagt ttgaatactg ggctatgccg cacaaagatg aaaaagtaat gccattcttt
     2161 gaacagcata aatcgttatt ccgtaatccg aagaaactcg cggatgttgt cgccagcctc
     2221 aacgctgata gcgaatatgc agcaatcttt gttcctggtg ggcatggcgc acttattggt
     2281 ttaccagaaa gccaggacgt ggctgccgct ttacagtggg caatcaaaaa tgaccgtttt
     2341 gttatctccc tttgccacgg tccggcagct tttctggcac ttcgccacag cgataaccca
     2401 ctgaatggtt attctatttg cgcattccca gacgccgcag acaaacaaac gccagatatt
     2461 ggctatatgc cgggtcatct cacctggtac ttcggcgaag agttgaagaa aatgggcatg
     2521 aacatcatta atgacgacat caccgggcga gtacataagg accgtaaact tctcaccggc
     2581 gacagtcctt ttgcagcgaa tgcgttgggt aaactggcgg cgcaggaaat gctggcagct
     2641 tacgcgagtt aatccctgtt acattgtaat gtaagcgcat aatcaatcgc agccacgtta
     2701 atactcacga cgtggctgcg ttttttcacg gttaacttat ggcgtactga agcccgatgt
     2761 taatttcttt gcggtaacgt aattcggaac acgttatgct tactgagata gtgatacgta
     2821 gcacttcctc catgtaattc ggcaatcgct ttgactaaag aaaggccaag tccctgacct
     2881 acggaatgac gcgaattatc tccccgccaa aatctacgga agagtttttc aggctcatta
     2941 attttcgttc caggactggc gatatcaata ttaagagaac cgttggcatc aagaaaactg
     3001 gttatatgaa tacgcgattt ttctggtgaa tatcgaatgg cgttaacaat aagattcgat
     3061 aacattcgtt gcagtaaaat tttatccgca aagatttgtt gattgcactt gaccttaaag
     3121 caaatctctt tctcgtctga aagatattca agatagtcca aaagattttc aacttcctta
     3181 ttgagagaaa gcgaatccag tttcaccaaa acattgtttt tgtctgccct ggcaagaaac
     3241 agtatattct ctgttaaccg cgaaatattt tccagctctt cgatgtttcc ggcaattgtt
     3301 ttttgatatt cagcgatact tctggtttga ctgagcgtaa cctgattctg acccagtaat
     3361 gcattaattg gcgttctaag ttcatgagcg agatcgtcag caaattgact aaggcgctca
     3421 aaatctttga ctaaagcatg atgcatttta ttcaacgcct gcccaagagg ttttagttct
     3481 ctcggtaatg cgttaacctc aaccggcact cggctatcgt tataattcag cgcttccgtt
     3541 acgccactca actttttgat ctctcgcaac cccgttctga ttaacaacgg acttaataat
     3601 gagcacaata taatgacgac aatgcaaatt ataatgctat taattttata ctgttcaagc
     3661 atattatgtc tggctgaagc caatttagcc acagtaaccg ttaatgatgg cgaaacttca
     3721 tcaatgttaa ttcgtaaagc atctatctct gtatcattaa taatgcttct gtaaatgcct
     3781 gctgcgctga ttgtctcact agcaggtatg ttatttaaca tgtcatcact gacatttgtc
     3841 cggttaacaa ttttattgat gccatcacca tgaatgatca agatatcctg actaacatcc
     3901 atcatccggt taaaatagac aggtaatgta tctggattta ccccatcaat taacaactgc
     3961 ttgatctgcg ctgtccggtt aatgagtgtt gtatcatcgc gccatttcaa ctcacttgcc
     4021 aggccattat agagagtcca tacaattcca gcgccagcaa cagacagcag aaatataaaa
     4081 agcaaggtta aacggacggt tatagataat cttttcatta tttttttacc gctacgaatg
     4141 aatagcccat cccccggatt gtggcgatta gcttttcagg aaaaggatca tcaacttttg
     4201 cgcggagcct gcgaatggcg acatccaccg tattggtatc actatcaaag ttgattcccc
     4261 aaatttcact cgcaataacc gttctgggta taatctcgcc agctctggag gccagtagcc
     4321 aaagtaactg aaactccttg cgcgtcagtg taatactgat attgtccctg ctcacacttt
     4381 gactgacaga gtccattttt aagccactga tttctaatgt tgaattcaaa gcgtgatgtt
     4441 gccttaattg tgcccgaacc cttgccagca actcagaaaa tgaaaaaggt tttaccagat
     4501 aatcatttgc tccactgtcc agccctctga ctctgtcatc gacagaatcc cttgctgtaa
     4561 ggcaaataac aggagtttgc tttgccgttc ttaacgtttg taagatctgc cagccatcca
     4621 tacccggaag cataatatcc agaatgatca atgcataatc atccttcagc gcaagataaa
     4681 gcccatctct gccatcagaa acggcatcaa tgacataacc cgcttcggaa agcccctgcg
     4741 ttacccattc ctgggtcctt tgattatctt caataagtag aatcttcatg aaaataatat
     4801 gccataaatc atatgttata gaaacaacct ggttcattac aaaattgtaa tgctgctgta
     4861 aggttaccct ggacgttttt tcgctatcct caaaactcat tcacatgaca aggatataaa
     4921 catgttaaag cgttatttag tactctcggt agcaacggca gcattttcat taccttcttt
     4981 ggtttatgcc gcacaacaaa acattcttag cgtgcacatt ttgaaccagc aaacaggaaa
     5041 acccgctgcc gacgtgacag tcactcttga aaagaaagcg gataacggct ggttacaact
     5101 taataccgcc aaaacagata aggatggacg aattaaggca ctgtggcccg agcaaactgc
     5161 gactactggc gattaccgtg tcgtatttaa aaccggggac tatttcaaga aacaaaatct
     5221 tgaaagtttc ttccctgaga tccccgttga atttcatatt aataaagtga acgagcatta
     5281 tcatgtgcct ttgttactca gccaatatgg gtattcaacc tatcgtggca gttaatgcgt
     5341 aaatatgtaa aagctgatct ctgctactgt tagggaggtg actccctgac agattaacag
     5401 taaacggctc ttgttggcta acgacaaaaa agtgtgatgg cttatgaaaa agaatcaatt
     5461 tttaaaagaa tcagatgtta cggccgagtc ggtattcttt atgaagcgtc ggcaggtgtt
     5521 aaaagcactg ggcatcagcg cagctgcatt ttctttgcct cacgctgcgc atgccgatct
     5581 gcttagctgg tttaaaggga acgatcgtcc gcccgccccc gccggaaaac cgctggagtt
     5641 cagcaagcct gccgcctggc aaaataacct gccactgacg ccagcagata aagtctccgg
     5701 ttataacaac ttctatgaat tcgggctgga taaagccgat cccgctgcta atgctggtag
     5761 cctgaaaacc gatccatgga cactgaaaat cagcggcgaa gtggcaaaac cattgaccct
     5821 cgatcatgat gatttaaccc gtcgcttccc gctggaagag cgtatttatc gtatgcgctg
     5881 cgtggaagcg tggtcgatgg tggtgccgtg gattggtttt ccgctacaca aattgctggc
     5941 gcttgccgaa cccaccagca atgcgaaata tgtcgctttc gaaacgattt atgcgccgga
     6001 acagatgcca ggccagcagg accgctttat cggcggcggg ctgaaatatc cttatgtcga
     6061 aggattgcgt ctcgacgaag caatgcatcc gctcacactg atgaccgtag gtgtttatgg
     6121 caaggcgtta ccaccgcaaa atggcgcgcc ggtgcgactg attgtgccgt ggaaatatgg
     6181 ctttaaaggg attaaatcga tcgtcagtat taagctgacc cgcgagcgtc cgccaaccac
     6241 ctggaatctg gcagcgcctg acgaatacgg tttttacgcc aacgttaatc cgcatgttga
     6301 tcacccgcgc tggtcacagg ctaccgaacg atttattggt tcaggcggca ttctcgatgt
     6361 tcagcgccag ccaacactac tgtttaatgg ttacgccgac caggtggcat cgctgtatcg
     6421 tggcctggat ttgcgggaga atttctaaat gcgcctgaca gcaaaacagg tgatatggct
     6481 gaaagtttgc ctgcatcttg ccggattgtt gccgtttctc tggctggtct gggcgatcaa
     6541 tcacggtgga ctaggtgccg atccggtgaa agatattcag cattttaccg gtcgcactgc
     6601 actgaaattt ttgcttgcgg ccttgttaat cacacctctg gcacgctacg caaaacagcc
     6661 gttattgata cgcactcgcc gcctgttagg cttatggtgc tttgcctggg cgacactgca
     6721 tttaaccagt tacgcattgc tggagttggg cgtgaataat ctggcgttat taggtaagga
     6781 gttaattacc cggccttatt taacgttagg aattatcagc tgggttattt tgcttgcttt
     6841 agcgttcact tcaacccagt cgatgcagcg aaaactcggc aaacactggc aacagttgca
     6901 taacttcgtc tatcttgtcg cgatcctgac cccaatacat tatctgtggt cagtgaagat
     6961 tatttcaccg cagccactca tctacgctgg gctggctgta ctgcttttag ccttacggta
     7021 taagaagttg ctttcccttt tcaaccggtt acgcaagcag gcccacaaca aattatctct
     7081 ataacttcat attgccgaca aacttcgcgt tatcccggcc ggatgcggcg cgag
//
LOCUS       DAFGPF010000187         7057 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFGPF010000187 DAFGPF010000000
VERSION     DAFGPF010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7057
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.187"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(201..1031)
                     /locus_tag="LSX49_004863"
     CDS             complement(201..1031)
                     /locus_tag="LSX49_004863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000948499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7171134.1"
                     /translation="MLSGNKKMIHYRENIYSLDNYERYITDSSLFENTGDGIIYTGIV
                     PLITVVEPVVSNQHSVLIIPGGGYRRIVYEREGLDVGRWIAGQGYTAFILSYRMPSVN
                     GYYSFADAKNALNFISYWAGMSERTFKSVGCMGFSAGGHLAGYITHLHYEEETSVRPD
                     WMALIYPVISLDRSIAHQGCRKRLLDAGESEYSASLENSVTEYMPPVFIVHATDDKDV
                     PVIHSLRYFNSIRDKGHHAEAHFFDKGGHGFGVSGKNGYPIEKWQSLLLEWLAEHKFH
                     "
     gene            complement(1035..2507)
                     /locus_tag="LSX49_004864"
     CDS             complement(1035..2507)
                     /locus_tag="LSX49_004864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7171135.1"
                     /translation="MDSCIQKKQVWYKHLSPRQWKIFGAAWTGYLLDGFDFVLISLVL
                     TEVQHEFGLTTIEAASLISAAFISRWFGGLAIGALSDKMGRRMAMVLSIVLFSLGTLA
                     CGLAPGYAVMFIARIVIGLGMAGEYGSSVTYVIESWPVHLRNKASGFLISGFSIGGGL
                     AAQVYSIVVPLWGWRSLFFVGMLPILFAFYLRKNLPESDDWQKRQQENKPVRTMVDIL
                     YREKNKYINILLSCIAFACLYVCFSGVTANAALITVMALCCAAVFISFIYQGMGKRWP
                     TGIMLMLVVMFCFLYGWPLQAFLPTWLKVDMQYSPETVALIFMLAGFGSAAGSCIGGF
                     MGDWLGTRKAYVISLLIGQLVIIPVFLVDRDYVWLLGLLIFTQQVFGQGIGALVPKII
                     SGYFNVEQRAAGLGFIYNVGSLGGACAPILGAVVASHTSLGTAMCSLAFILTFVVLVL
                     IGFDMPSRVQRWIHPEAALEYDTVDGKPFYGARKKNVAEE"
     gene            complement(2556..3431)
                     /locus_tag="LSX49_004865"
     CDS             complement(2556..3431)
                     /locus_tag="LSX49_004865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000629094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HBL7171136.1"
                     /translation="MITLAVDIGGTKISAALISDDGSFLLKKQISTPHERCPDEMTGA
                     LRLLVSEMKGTAERFAVASTGIINNGVLTALNPDNLGGLKEYPLKNIMEDITGLNGSV
                     INDAQAAAWAEYTVLPKEICDMVFITVSTGVGGGIVVNRKLLTGVSGLAGHVGHILSG
                     VTDTECGCGRRGCVEAVSSGRAIMGAAKNKLAGYSTKYIFELARQGYKEAEFLTERSA
                     STIAELIVSLKLLLDCQVVVVGGSVGLADGYVQKVSKHLSIYSEICNVMLFPAYFRSD
                     SGLIGATLWDRDCIT"
     gene            complement(3465..4382)
                     /locus_tag="LSX49_004866"
     CDS             complement(3465..4382)
                     /locus_tag="LSX49_004866"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBL7171137.1"
                     /translation="MQCEFKGVISALPTPYDQSQQIDMESLRKLIRFNIEQNIKGLYV
                     GGSTGEAFLQNVAEREKILETVADESDGRLTLIAHVGGISTAESEVLAKAAKKYGYHA
                     ISAVTPFYYPFSFEEHCIHYRKIIDSADGLPMVVYNIPALSGVRFSLDQINELVTIPR
                     VCALKQTSGDLFQMEQIKRNHPELVLYNGYDEIFASGLIAGADGGIGSTYNIMGWRYL
                     EIFEAVKNNDVIKAKEMQVACNQVIDTLIQSGVLAGIKTLLYYMGIINTPVCRSPFSP
                     VKEKNLDVLSKLAERLFEEHDRNKKMKII"
     gene            4534..4671
                     /locus_tag="LSX49_004867"
     CDS             4534..4671
                     /locus_tag="LSX49_004867"
                     /inference="COORDINATES: protein motif:HMM:NF024407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HBL7171138.1"
                     /translation="MQCPVTILCVTLCDYLAPELITHSPEESDTVTLRKRRLPLEMMA
                     W"
     gene            5043..5468
                     /locus_tag="LSX49_004868"
     CDS             5043..5468
                     /locus_tag="LSX49_004868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL7171139.1"
                     /translation="MEQKILSAEPRRTFSNEFKLQMVKLASQLGASVARIAREHDIND
                     NLLFKWLRLWQNEGRISRRLPVTTSSDAGVELLPVEITPDEQKEPMAALTPLLSTPSQ
                     STVSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
     gene            5465..5815
                     /gene="tnpB"
                     /locus_tag="LSX49_004869"
     CDS             5465..5815
                     /gene="tnpB"
                     /locus_tag="LSX49_004869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL7171140.1"
                     /translation="MISLPSDTRISLVAGVTDMRKSFNGLGEQVQHVLDENPFSGHLF
                     IFRGRRSDMIKILWADADGLCLFTKRLEEGLFIWPAVRDGKVSITRSQLAMLLDKLDW
                     RQPKTSRLNALTML"
     gene            5846..6943
                     /locus_tag="LSX49_004870"
                     /pseudo
     CDS             5846..6943
                     /locus_tag="LSX49_004870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT         2093 a         1775 c         1387 g         1802 t
ORIGIN      
        1 caccaaccat tattccaccc ctgactaacc tgaatcaacg tttcataagc gtgactggcg
       61 cttctgtatc ccccacgtag attaagagtt aatgcctgag agcacaaagg taaaccaaga
      121 agaattacag ttaatagtgg ataatatttt ttcataaatg cctcatcatt aaatatattt
      181 atcacttgta atttgatttc tcaatgaaac ttatgttccg caagccattc cagaagcagg
      241 ctttgccatt tttctatcgg atatccattt tttccggata caccaaatcc atgacctccc
      301 ttatcaaaaa aatgagcttc tgcatgatgt cccttatccc gaatagagtt aaaatatctc
      361 agagaatgaa taactggaac atccttatca tctgttgcat gcacaataaa gactggtggc
      421 atatactctg taacactatt ttcaagactg gctgaatatt cactttcacc tgcatccaga
      481 agacgtttcc ggcatccctg atgagcaata ctcctgtcaa gagatataac tggatatatc
      541 agagccatcc agtcaggacg cacagaagtc tcttcctcat aatggagatg agtaatatat
      601 ccagcaagat gaccacctgc cgaaaacccc atacatccaa cactcttaaa tgttctctcc
      661 gacattccgg cccagtaaga aataaagttc agggcattct tcgcatctgc aaaggaataa
      721 taaccattaa cggagggcat tctgtaagaa agaataaatg ccgtatatcc ctgacctgct
      781 atccatctgc caacatcaag tccctctctt tcataaacaa tcctcctgta tccacctcca
      841 ggtataatca gcacactatg ttgattagat acaacaggct caacaactgt aataaggggc
      901 acaatacctg tatatattat gccatcgcca gtattctcaa atagcgaact gtcagttatg
      961 taacgctcat aattatcaag agaatatata ttctccctgt aatgaatcat ttttttattc
     1021 cctgatagca tccgttattc ttctgcaaca ttcttttttc ttgctccata aaaaggtttt
     1081 ccatcgacag tatcatattc aagcgcagct tctggatgga tccatctctg tacacgtgat
     1141 ggcatatcaa aaccaataag gacaagaaca acaaatgtta agataaaagc aagagaacac
     1201 attgctgtac caagacttgt atgagacgca acaactgcac caagaatagg cgcacatgct
     1261 ccaccaagtg aacctacatt ataaataaac cccagtcctg ccgcacgctg ctccacatta
     1321 aaataaccac tgattatttt cggcaccaga gcaccaatcc cctgaccaaa aacctgctga
     1381 gtaaagatta gaaggccaag taaccataca tagtcccggt ccacaagaaa aacggggata
     1441 ataacaagct gaccgataag aagtgatata acatatgctt ttcgggttcc aagccagtcc
     1501 cccataaaac cacctataca acttccagct gcagagccaa aacctgccag cataaatatg
     1561 agagcaacag tttctggtga atactgcata tcaaccttaa gccatgtagg aagaaaagcc
     1621 tgcagtggcc atccgtagag gaaacagaac ataaccacaa gcatcaacat aatgcctgtt
     1681 ggccatcttt tccccatacc ctgatatata aaactgataa aaacagccgc acagcacaat
     1741 gccataactg tgattaaagc agcgtttgca gtgacgcctg aaaaacaaac atatagacat
     1801 gcaaatgcaa tacaagacag aagaatattt atgtatttat tcttttctct gtacagaata
     1861 tccaccattg ttctgacggg tttattctct tgttgccttt tttgccagtc atcagactcc
     1921 ggaagattct tgcgaagata aaaagcaaat aatattggaa gcatgccgac aaagaaaaga
     1981 gaacgccagc cccatagtgg tactacaatg ctataaacct gtgcagctaa acctccccca
     2041 atagaaaatc cagaaattaa aaaaccactt gccttgtttc tgagatgaac aggccagctt
     2101 tcgataacat atgttacact tgagccatat tcacctgcca taccaagccc aataacaatg
     2161 cgagcaataa acatcactgc atatccagga gccagaccac aggcaagggt tccgagagag
     2221 aatagcacta tacttaaaac cattgccatc ctgcgcccca tcttgtccga taaagcgcca
     2281 atagcaagcc ccccaaacca tcgagaaata aaagcagcgg aaataaggct tgccgcttct
     2341 attgtcgtca agccgaattc atgctgaacc tctgtaagaa ccagagatat cagaacgaaa
     2401 tcaaaaccat caagtaaata acctgtccat gccgcaccga atatcttcca ctgtctgggt
     2461 gaaagatgct tataccaaac ctgctttttc tgaatacagg agtccatatt aaacctcaca
     2521 ataatagcgg atttataata cactggagta ttactttaag taatacaatc ccggtcccaa
     2581 agagttgcac caataagacc agagtcactt ctgaaatatg caggaaacag cattacatta
     2641 caaatttcag aatatatgga aagatgtttc gacactttct gaacataccc atcagcaagt
     2701 ccaacacttc ctccgacaac aacaacctga caatcaagca gtaattttaa acttactatt
     2761 aattcagcaa tagtactggc agaacgctct gtcaaaaatt ctgcttcctt atatccctgt
     2821 ctcgctaatt caaaaatata tttggtgcta tatcctgcaa gtttattttt tgctgccccc
     2881 atgatggccc gaccagatga aaccgcttca acgcatcccc gacgaccaca tccacattct
     2941 gtatccgtta ctccggacaa tatatgccca acatgtccgg ctaatccaga aacacctgtt
     3001 aataattttc tgttaactac aattccccct ccaacccccg tagaaacggt tataaaaacc
     3061 atatcacaaa tttctttcgg caaaactgta tattctgccc atgcggctgc ctgggcatca
     3121 tttatcacac ttccatttaa accagttata tcttccatta tatttttcag aggatactct
     3181 ttcagccctc caagattgtc tggattcaga gctgtcaata ctccattatt aataatccct
     3241 gttgatgcta ctgcaaatcg ctccgctgtt cccttcattt cagaaaccag tagacgtaaa
     3301 gcccctgtca tttcgtcagg acatctttca tgaggtgttg atatctgttt tttcagcaaa
     3361 aatgaaccgt catcagatat caacgccgct gaaattttcg ttcctcctat atcaacagcc
     3421 agtgttatca ttcattttca cctatataac aatcttgcaa ttattcagat tattttcatt
     3481 tttttgtttc tgtcatgttc ttcgaacagt cgctctgcaa gttttgataa tacatccaga
     3541 ttcttttcct ttaccggaga aaaaggactt ctgcatacag gagtatttat aatccccata
     3601 tagtaaagaa gagtttttat acctgccagg acaccactct gaataagagt gtcaataacc
     3661 tggttacagg ctacttgcat ttccttcgcc ttaatcacat cattgttttt gactgcttca
     3721 aatatttcaa gataacgcca ccccattata ttatatgtac taccgattcc cccatctgca
     3781 cctgcaatta accctgatgc aaatatttca tcgtaaccat tatataacac aagctctgga
     3841 tgattccttt tgatttgttc catctggaat aaatcaccgg atgtctgttt taatgcacaa
     3901 accctgggta ttgtgacaag ctcatttatc tgatctaaag aaaaacgcac tccgctaaga
     3961 gccggtatat tataaactac catcggaagt ccatctgcag aatcaataat cttcctgtaa
     4021 tggatacaat gctcttcaaa tgaaaaagga taataaaatg gagtaacagc agatatagca
     4081 tgatatccgt atttttttgc agcttttgca agtacctcgc tttctgccgt actgattccg
     4141 cccacatgcg ctataagtgt cagtcttcca tctgattcat cggctactgt ttcaagaatt
     4201 ttttctcgct ctgcaacatt ctgaagaaat gcttctccag tagagcctcc aacatacaat
     4261 cccttaatat tttgttcgat attaaaacgg atcagttttc gaagactctc catatcgatt
     4321 tgctgggatt ggtcataagg agtgggtaat gctgatatga cccctttaaa ttcacattgc
     4381 atttttaatc accttcactt aactgcataa tgggatacct agtacaccat caagtacaaa
     4441 gattatccaa cagaaaagaa gcacaatgtg aagattatca aaaaaaaacc atcagaaagc
     4501 tgtcatgccg ctcagttaag gatcggttga tcgatccagt gtccagttac tattctctgc
     4561 gtaaccctct gcgactatct tgccccggaa ctgattaccc acagccctga agagtccgac
     4621 actgtcacgc tacgcaaacg gcgtcttcct ctggaaatga tggcctggtg aattatcagt
     4681 atggcccatg agcgtaagga accttcacca gattgtgaac cggctggaca catgctgcca
     4741 ggtagtcgcc cctttgtcgc gccgtgatcc atgcccagca gggccaggaa gcggggccgt
     4801 acgccacgtg ttcacgtaaa cagcgcagcc ctgacataac accacgctgt atccgctctg
     4861 gtgcaatatg aacctgctga ccatcgatgg cgtgttctaa ctaacacagg acacgccaga
     4921 acacgacata aagcttcact cgccagatac atggtaagcg taaactgacc gccgtatgta
     4981 gccattaagc cagtattggt aacgtaggtg cccacctttt catcaactag tggacacctg
     5041 ttatggaaca gaaaatatta tccgcagaac cccgcagaac attttcaaat gagtttaaac
     5101 ttcaaatggt taaactggct tcacaactag gagcctctgt tgcccgtatt gccagggaac
     5161 acgatatcaa tgataacctc ctgttcaaat ggctcaggct ctggcagaac gaagggcgta
     5221 tatcgcggcg tcttccggta acaacctctt ctgacgctgg cgttgaatta ttacctgttg
     5281 agataacgcc tgatgagcag aaagagccta tggcggctct tactccgctt ttatccactc
     5341 cttcacaaag cacagtcagt gccagttcct gtaaagttga gttccgccac ggtaacatga
     5401 cgctggaaaa tccttcacca gagctgctca cggtgttgat ccgtgaactg accgggaggg
     5461 ggcgatgatc tcgctcccat cagacactcg aatctcgctg gttgccggcg ttactgatat
     5521 gcgtaaatcc ttcaacggtc tgggtgaaca ggtacaacat gtgctggatg agaacccctt
     5581 ctccggtcac ctgttcatct tccgtggccg acggagtgac atgattaaaa tcctctgggc
     5641 tgatgctgat ggtctgtgcc tgttcaccaa acgcctggag gaaggcctgt ttatctggcc
     5701 tgcggtgcgt gacggtaagg tatccattac ccgctcgcag ctggcaatgc tcctcgataa
     5761 gctggactgg cgtcagccaa aaacatcccg tcttaacgca ctgacaatgt tgtaaaaatg
     5821 tcatggccgg attataaaaa cggtcatgag tcggaaatac ctcattcgta tcactgagct
     5881 ggaaaggctg ctctctgagc aggctgaagc cctccgtcag agagatctgc aactgagtct
     5941 ggttgaagag acggaggcct tcctgcgctc tgcactggca cgtgccgaag aaaagatcga
     6001 agaggaggag cgggaaatag aatatctgag ggcccagata gaaaaactgc gccggatgct
     6061 gttcggtacc cgttctgaaa aactgcagcg tgaggttgaa caggctgagg cccaactgaa
     6121 acaacgcgaa caggaaagcg atcgttacag tgggcgtgag gatgacccgc aggttccccg
     6181 ccagttgcga cagtcacgtc atcgtcgtcc gttaccagca catcttcccc gtgaaataca
     6241 ccgcctggag cctgaagaaa gttgttgccc ggagtgtggc agtgagctgg attatctggg
     6301 tgaagtcagt gctgagcagc tggaactggt gagtagcgcc ctgaaagtga tccgcactgt
     6361 tcgggtaaaa aaagcctgta caaaatgtga ctgtatagtt gaagcgccag cgccgtcccg
     6421 cccgatagcg cgcggcatcg cgggctccgg attacttgcc cgcgtgttaa cgggaaaata
     6481 ctgcgaacac ctgccactgt atcgtcagag tgaaatcttt gcccgacagg gtgccgaact
     6541 gagccgtgca ttaatctcca actgggttga cgcgtgctgc cagttaatga ctccgctaaa
     6601 tgatgccctg taccgttacg tgatgaacac ccgcaaggtt cacactgacg acacaccggt
     6661 aaaagtgctg acaccgggca gaaaaaaggc aaaaacagga cgcatctgga cgtatgtccg
     6721 ggatgaccgg aatgcgggct catcagagcc accggcggtc tggttcgcct actcaccaga
     6781 caggcaggga aaacatccgg tacaacacct tcgtcccttc cggggtatcc tgcaggcgga
     6841 tgcattcagc ggttacgatc ggctgttcag tgccaaacgt gaaggtgatg cacagacaga
     6901 agttgcgtgc tgggtccatg cccggcgaaa aatacacgat gtatgaacga catctcttct
     6961 gacgacattt tcctgctgaa acagcgcctg gccgaacagg aagcgctgat ccacgccctg
     7021 caggaaaagc tgagcaaccg ggagcgcgaa atagacc
//
LOCUS       DAFGPF010000188         7045 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFGPF010000188 DAFGPF010000000
VERSION     DAFGPF010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7045
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.188"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            556..1545
                     /gene="araF"
                     /locus_tag="LSX49_004871"
     CDS             556..1545
                     /gene="araF"
                     /locus_tag="LSX49_004871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein AraF"
                     /protein_id="HBL7171141.1"
                     /translation="MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEW
                     KFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKAR
                     GYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
                     MAITSNELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPE
                     VKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLL
                     PSPDVHGYKSSEMLYNWVAKGVEPTKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            1615..3129
                     /gene="araG"
                     /locus_tag="LSX49_004872"
     CDS             1615..3129
                     /gene="araG"
                     /locus_tag="LSX49_004872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP binding protein
                     AraG"
                     /protein_id="HBL7171142.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTNMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     LCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPG
                     AEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGV
                     AVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA"
     gene            3144..4130
                     /gene="araH"
                     /locus_tag="LSX49_004873"
     CDS             3144..4130
                     /gene="araH"
                     /locus_tag="LSX49_004873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter permease AraH"
                     /protein_id="HBL7171143.1"
                     /translation="MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPN
                     FATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESL
                     WIGVAAGLLLGILCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
                     SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVV
                     RTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKI
                     SYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            4297..5097
                     /gene="otsB"
                     /locus_tag="LSX49_004874"
     CDS             4297..5097
                     /gene="otsB"
                     /locus_tag="LSX49_004874"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HBL7171144.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDTILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     ARDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPKGTSKGEAITAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            5072..6496
                     /gene="otsA"
                     /locus_tag="LSX49_004875"
     CDS             5072..6496
                     /gene="otsA"
                     /locus_tag="LSX49_004875"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HBL7171145.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNKFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTACGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(6503..6931)
                     /gene="uspC"
                     /locus_tag="LSX49_004876"
     CDS             complement(6503..6931)
                     /gene="uspC"
                     /locus_tag="LSX49_004876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HBL7171146.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRNVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCRKHH
                     FDLVICGNHNHSFFSRASCSAKRVITSSEVDVLLVPLTGG"
BASE COUNT         1763 a         1640 c         1837 g         1805 t
ORIGIN      
        1 gccttttgta tcttattgat attaatcgat gaatttgaat tcatgatgag gcaatgattt
       61 tataaaacgt tttttcattt ttgcgatatg gctctcatta tacgtgttct gttaattaat
      121 gagcacagtg ataattaatg gcgaaatgaa tgacgcgcat tttccacatc tttaagttgc
      181 ggttattaca ccattgcaaa aactcaacgc caggtaatga ggcctattga ctggttaaaa
      241 agaagacatc ccgcatgggt accaaagaca acaaggactt ccaggctaat cttatggatt
      301 attctgctgt gcactcgata atttgtctga caaattcgct tttccttatg tcttttcccg
      361 ctaaatttat gcacgttctc actgtaattc tgcgatgtga tattgctctc ctatggagaa
      421 ttaatttctc gctaaaacta tgtcaacaca gtcacttatc ttttagttaa aaggtaatgc
      481 tttgttttcc gattaattta acgaatgtca ttcgtttttg ccctacacaa aacgacacta
      541 aagctggaga gaaccatgca caaatttact aaagccctgg cagccattgg tctggcagcc
      601 gttatgtcac aatccgctat ggcggagaac ctgaagctcg gtttcctggt gaagcaaccg
      661 gaagagccgt ggttccagac cgaatggaag tttgccgata aagccgggaa ggatttaggg
      721 tttgaagtta ttaagattgc cgtgccggat ggcgaaaaaa cattgaacgc tatcgacagc
      781 ctggccgcca gtggcgcgaa aggtttcgtt atttgtactc cggacccgaa actcggctct
      841 gccatcgtgg cgaaagcgcg tggctacgat atgaaagtca ttgccgtgga tgaccagttt
      901 gttaacgcca aaggtaagcc aatggatacc gttccgttgg tgatgatggc tgcgaccaaa
      961 attggcgaac gtcagggcca ggaactgtat aaagagatgc agaaacgtgg ctgggatgtc
     1021 aaagaaagcg cggtgatggc gattacctcc aacgaactgg atacggctcg tcgccgtact
     1081 acggggtcta tggatgcgct gaaagctgca ggattcccgg aaaaacaaat ttatcaggta
     1141 ccgaccaaat ctaacgacat cccgggggca tttgacgctg ccaactcaat gctggttcaa
     1201 catccggaag ttaaacattg gctgattgtc ggtatgaacg acagcaccgt gctgggcggc
     1261 gtacgcgcga cggaaggtca gggctttaaa gcggccgata tcatcggtat cggtattaac
     1321 ggtgtggatg cggtgagtga actgtctaag gcgcaggcaa ccggcttcta cggttccctg
     1381 ctgccaagcc cggacgtaca tggttataag tccagcgaaa tgctttacaa ctgggttgca
     1441 aaaggtgttg aaccgaccaa attcaccgaa gttaccgacg tggtgctgat cacgcgtgac
     1501 aactttaaag aagaactgga gaaaaaaggt ttaggcggta agtaatttgc cggaaaaatt
     1561 cccctctgca tgatgcagag ggggtgtgaa cgaccagtga ttcacggaga cgttatgcaa
     1621 cagtctaccc cgtatctctc atttcgcggc atcggtaaaa cgtttcccgg cgttaaggcg
     1681 ctgacggata ttagttttga ctgctatgcc ggtcaggttc atgcgttgat gggtgaaaat
     1741 ggcgcaggaa aatcaactct cttaaaaatc ctcagcggaa actatgcgcc aaccacgggt
     1801 tctgtagtga ttaatgggca ggaaatgtcc ttttccgaca cgaccgcagc acttaacgcg
     1861 ggtgtggcga ttatttatca ggaactgcat ctcgtgccgg aaatgaccgt cgcggaaaat
     1921 atctatctcg gccagctgcc gcataaaggc ggcattgtga atcgttcatt gctgaattat
     1981 gaggcaggtt tacaacttaa acatcttggt atggatattg acccggacac gccgctgaaa
     2041 tatctctcca ttggtcagtg gcagatggtt gaaatcgcca aagcgctggc gcgtaacgcc
     2101 aaaattatcg cctttgatga gccaaccagc tccctctctg cccgcgaaat cgacaatctt
     2161 ttccgcgtta ttcgtgaatt gcgaaaagag gggcgggtga tcttatacgt ttctcaccgt
     2221 atggaagaaa tatttgccct cagcgatgcc atcaccgtct ttaaagatgg gcgttatgtc
     2281 aaaactttta ccaatatgca gcaggttgac cacgacgcac tggtgcaggc gatggtcggg
     2341 cgagacattg gcgatatcta cggctggcaa ccgcgtagtt atggcgagga gcggctgcgt
     2401 cttgatgctg tgaaagcacc aggcgtgcgt acgccaataa gtctggcggt tcgcagtgga
     2461 gaaattgtcg gtctgtttgg tctggtcggg gcagggcgta gcgaattaat gaaaggcatg
     2521 tttggcggga cgcaaatcac cgccggtcag gtttatatcg accaacagcc gatcgatatt
     2581 cgtaaaccga gccacgccat tgccgcaggc atgatgctct gcccggaaga tcgcaaagcg
     2641 gaaggcatta ttcccgtgca ctccgttcgc gacaatatca acatcagtgc cagacgtaaa
     2701 catgtgcttg gcggttgtgt aatcaacaac ggttgggaag aaaacaatgc cgatcaccac
     2761 attcgttcgc tcaacatcaa aacgccgggc gctgagcaac tgatcatgaa tctctcaggc
     2821 ggaaatcagc aaaaagccat tctgggccgc tggttatcgg aagagatgaa ggtcattttg
     2881 ctggatgaac ctacgcgtgg cattgatgtt ggtgctaagc atgaaattta caacgtgatt
     2941 tatgcgctgg cggcgcaggg tgtggcggtg ctgtttgcct ccagcgactt acctgaagtc
     3001 ctcggcgttg ccgaccggat tgtggtgatg cgggaaggcg aaatcgccgg tgaattgtta
     3061 cacgagcagg cagatgagcg tcaggcactg agccttgcga tgcctaaagt cagccaggca
     3121 gttgcctgag taaggagagt atgatgtctt ctgtttctac atcgggttct ggcgcaccta
     3181 agtcgtcatt cagcttcggg cgtatctggg atcagtacgg catgctggtg gtgtttgcgg
     3241 tgctttttat cgcctgtgcc atttttgtcc caaattttgc caccttcatt aatatgaaag
     3301 ggttgggcct ggcaatttcc atgtcgggga tggtggcttg tggcatgttg ttctgccttg
     3361 cttccggtga ctttgacctt tctgtcgcct ccgtaattgc ctgtgcgggt gtcaccacgg
     3421 cggtggttat taatctgact gaaagcctgt ggattggcgt ggcagcgggg ttgctgctgg
     3481 gcattctctg tggtctggtc aatggctttg ttatcgccaa actcaaaata aatgccctga
     3541 tcacgacact ggcaacgatg cagattgttc gaggtctggc gtacatcatt tcagacggta
     3601 aagcggtcgg tatcgaagat gaaagcttct ttgcccttgg ttacgccaac tggttcggtc
     3661 tgcctgcgcc aatctggctc accgtcgcgt gtttgatcat ctttggcttg ctgctgaata
     3721 aaaccacctt tggtcgtaat accctggcga ttggcgggaa cgaagaggct gcgcgtctgg
     3781 cgggtgtacc ggttgttcgc accaaaatta ttatctttgt tctctctggc ctggtatcag
     3841 cgatagccgg aattattctg gcttcacgta tgaccagtgg gcagccaatg acgtcgattg
     3901 gttatgagct gattgtgatc tccgcctgcg ttttaggtgg cgtttctctg aaaggcggca
     3961 tcggaaaaat ctcatatgtg gtggcgggta tcttaatttt aggcaccgtg gagaacgcca
     4021 tgaacctgct taatatttct cctttcgcgc agtacgtggt tcgcggctta atcctgctgg
     4081 cagcggtgat cttcgaccgt tacaagcaaa aagcgaaacg cactgtctga tgcttttttc
     4141 tgcaacaatt tagcgctttt ttcctccaca gccagccgcc acaacggttg gctgttcttc
     4201 gttacaaatg gcgacccccg tcacactgtc tatacttaca tgtctgtaaa gcgcgttctg
     4261 cgcaacacaa taagaaaaga gaaggaggag aaccgggtga cagaaccgtt aaccgaaacc
     4321 cctgaactat ccgcgaaata tgcctggttt tttgatctcg atggaacgct ggcggaaatc
     4381 aaaccgcatc ccgatcaggt cgtcgtgcct gacactattc tgcaaggact tcagctactg
     4441 gcaaccgcaa gtgatggtgc attggcattg atttcagggc gctcaatggt ggagcttgac
     4501 gcactggcaa aaccttatcg cttcccatta gcgggcgtgc atggggcgga gcgccgtgac
     4561 atcaatggta aaacgcatat cgttcatctg ccggatgcga ttgcgcgtga tattagcgtg
     4621 caactgcata cggtcatcgc ccagtatccc ggcgcggagc tggaggcgaa agggatggct
     4681 tttgcgctgc attatcgcca ggctccgcag catgaagacg cattaatgac attagcgcaa
     4741 cgtattactc agatctggcc acaaatggcg ttacagcagg gaaagtgtgt tgtcgagatc
     4801 aaaccgaaag gtaccagtaa aggtgaggcg attactgcct ttatgcagga agctcccttt
     4861 atcgggcgaa cgcccgtatt tctgggcgat gatctaaccg atgaatctgg cttcgcagtc
     4921 gttaaccggc tgggcggaat gtcagtaaaa attggcacag gtgcaactca ggcatcatgg
     4981 cgactggcgg gcgtgccgga tgtctggagc tggcttgaaa tgataaccac cgcattacaa
     5041 caaaaaagag aaaataacag gagtgatgac tatgagtcgt ttagtcgtag tatctaaccg
     5101 gattgcacca ccagacgagc acgccgccag tgccggtggc cttgccgttg gcatactggg
     5161 ggcactgaaa gccgcaggtg gactgtggtt tggctggagc ggtgaaacag ggaatgagga
     5221 tcagccgcta aaaaaggtga aaaagggtaa cattacgtgg gcctctttta acctcagcga
     5281 acaggacctt gacgaatact acaacaaatt ctccaatgcc gttctctggc ccgcttttca
     5341 ttatcggctc gatctggtgc aatttcagcg tcctgcctgg gatggctatc tacgcgtaaa
     5401 tgcgttgctg gcagataaat tactgccgct gttgcaagac gatgacatta tctggatcca
     5461 cgattatcac ctgttgccct ttgcgcatga attacgcaaa cggggagtga ataatcgcat
     5521 tggtttcttt ctgcatattc ctttcccgac gccggaaatc ttcaacgcgc tgccgacata
     5581 tgacaccttg cttgaacagc tttgtgatta tgatttgctg ggtttccaga cggagaacga
     5641 tcgtctggcg ttcctggatt gcctttctaa cctgacccgc gtcacgacac gtagcgcaaa
     5701 aagccatacg gcctgcggca aagcgtttcg aacggaagtt tacccgatcg gcattgagcc
     5761 gaaagaaata gcgaaacagg ctgccggtcc actgccgcca aaactggcgc aactcaaagc
     5821 agaactgaaa aacgtacaaa atatcttttc tgtcgaacga ctggattatt ccaaaggttt
     5881 gccggagcgt tttctcgcct atgaagcgtt actggaaaaa tatccgcaac atcacggtaa
     5941 aattcgttat acccagatcg cgccaacgtc tcgtggtgat gtgcaagcct atcaggatat
     6001 tcgtcatcag ctcgaaaatg aagccggacg aattaatggt aaatatgggc aattaggctg
     6061 gacgccgctt tattatttga atcagcattt tgaccgtaaa ttactgatga aaatattccg
     6121 ctactctgac gtgggcttag tgacgccact gcgtgacggg atgaacctgg tggcaaaaga
     6181 gtatgttgcc gctcaggacc cagccaaccc gggcgttctt gttctttcgc aatttgcggg
     6241 agcggcaaac gagttaacgt cggcgttaat tgttaatccc tacgatcgtg acgaagttgc
     6301 agctgcgctg gatcgtgcat tgactatgtc gctggcggaa cgtatttccc gtcatgcaga
     6361 aatgctggac gttatcgtga aaaacgatat taaccactgg caggagtgct tcattagcga
     6421 cctaaagcag atagttccgc gaagcgcgga aagccagcag cgcgataaag ttgctacctt
     6481 tcctaagctt gcgtaggtgc ggttaacctc ccgtaagtgg aactaacagc acatcgacct
     6541 cacttgaggt aatcactctt ttcgccgagc aggatgctcg cgaaaagaaa ctgtgattgt
     6601 gattaccgca aatcaccaaa tcgaaatgat gtttgcgaca aacttccaga atatgttcgc
     6661 ttaactcacc gtaggcaata aacgtcttgt caacgggata ccccgcatcc tgaattaact
     6721 tatcaagaaa gctttgcgtt tcttcctgca tcacgttgcg taaatcttca agcatcggcg
     6781 cagctaattg attgtacatt tccgggtcgg aagcgagagt aattaaactg atgtgtccct
     6841 ttactggcct ggcgatagat accgcttttg ccagcagttg ctgactttcc ggtgtaaccg
     6901 caacggcgac aagaatattg ctatagctca taacctgttc cttattctgt gaacttcagg
     6961 tgacattaaa gctttactcc taatggagaa acgacgcaat cccaactcag ttaaacaggt
     7021 aaatattagt ctggtcatta gtaaa
//
LOCUS       DAFGPF010000189         7042 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFGPF010000189 DAFGPF010000000
VERSION     DAFGPF010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7042
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.189"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(240..1253)
                     /locus_tag="LSX49_004877"
     CDS             complement(240..1253)
                     /locus_tag="LSX49_004877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL7171147.1"
                     /translation="MSTRIYLWRALFGEKPRILLENSDFTVTSFRYDSGVEGLKIANS
                     RGHLIILPWMGQMIWDAQFDGHSLTMCNMFRQPKPATEVIETYGCFAFHSGLLANGCP
                     SAEDTHLLHGEMACAAMDEAWMELEGDMLRLTGRYEYVMGFGHHYLAQPTVVLHRSST
                     LFDIKMAVTNLASVDMPLQYMCHMNYAYIPNATFSQNIPDEILRLRESVPSHVNPTAQ
                     WLAFNQRIMQGEASLSTLNQPEFYDPEIVFFADKLDAYTDLPEFRMIAPDGTTFVTRF
                     SSAELNYVTRWILYNGEQQVAAFALPATCRPEGYLAAQRNGTLIQVAPQQTRTFTVTT
                     GIE"
     gene            complement(1265..2581)
                     /gene="fucP"
                     /locus_tag="LSX49_004878"
     CDS             complement(1265..2581)
                     /gene="fucP"
                     /locus_tag="LSX49_004878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HBL7171148.1"
                     /translation="MNDKNIIQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIGGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     ASGILLGKYLVFSEGESLEKQMSGMNAEQIHNFKVLMLENTLEPYKYMIMILVVVMVL
                     FLLTRFPTCKVAQTSHHKRPSAMDTLRYLAKNSRFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASNFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNQHTEMAGAVIVMAIVGAAVVPA
                     IQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRNALAEVTES"
     gene            complement(2609..3529)
                     /gene="rbsK"
                     /locus_tag="LSX49_004879"
     CDS             complement(2609..3529)
                     /gene="rbsK"
                     /locus_tag="LSX49_004879"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL7171149.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHAIEFGKKNGIEVL
                     LNPAPALRELDMSYACKCDFFIPNETELEILTGMSVDTYDHIRLAARSLVDKGLNNII
                     VTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAA
                     LFAAFSVTGKGTQSSYPSIEQFNEFLTLNE"
     gene            3835..4617
                     /locus_tag="LSX49_004880"
     CDS             3835..4617
                     /locus_tag="LSX49_004880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL7171150.1"
                     /translation="METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLHQ
                     EDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAAGMVNENDLIFFDN
                     GQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNS
                     SPLDSLNPRKIFISASGVHNHFGVSWFNPEDLATKRKAMNRGLRKILLARHALFDEVA
                     SASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE"
     gene            complement(4619..4845)
                     /locus_tag="LSX49_004881"
                     /pseudo
     CDS             complement(4619..4845)
                     /locus_tag="LSX49_004881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229544.1"
                     /note="with IlvB catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase small
                     subunit; frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
     gene            5843..5950
                     /locus_tag="LSX49_004882"
     CDS             5843..5950
                     /locus_tag="LSX49_004882"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL7171151.1"
                     /translation="MGNMAPFILRGVTLKGIDSVMFAKEKRAAIWQQAV"
     gene            complement(6131..6787)
                     /locus_tag="LSX49_004883"
     CDS             complement(6131..6787)
                     /locus_tag="LSX49_004883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7171152.1"
                     /translation="MTGENRGRGRPRKTESTYADTRNDLIRSGLELLTQNGFLATGVD
                     AIVKNANVPKGSFYYYFKSKEDYAQTVLNAYDSFFEHKLKKHLHESSCTPMVRLENFI
                     NDACEGIKKYNFTRGCLVGNMMQESPGLPQSFIKVLQNILESWQALVAACLSDALSSG
                     EISSNMNNTQLAAIFWSGWEGAVMRSKLYCSTEPVYDFWSYFKTSVRYQSSQEATTGQ
                     "
BASE COUNT         2011 a         1646 c         1505 g         1880 t
ORIGIN      
        1 gtttttgttg accactacaa ataaataaaa gagttgcagt gcttgctcgg taagaaaaca
       61 atggaagttg agatcctaaa agaagctgtg gagtacacca ctctacagta gttgcgcaaa
      121 tttggagtgg acgataatgt gatcgtctat aagggcaacg ctatcatagt cttgtcctgg
      181 cgggtaaaaa aacgcgctta ccttaacgat aagcgcgccg ctgttcaggc cttaagtggt
      241 tattcaattc ctgtggtgac tgtaaaagtg cgtgtttgct gcggtgcaac ctgaatcagc
      301 gtgccattac gttgcgcggc aagatacccc tcaggccgac aggttgcagg taatgcaaag
      361 gcggctacct gttgctcgcc gttataaagg atccagcgtg tcacataatt tagttcggca
      421 ctggagaaac gagtaacaaa cgtagtgcca tcgggagcga tcatgcgaaa ctctggcaga
      481 tctgtgtaag cgtccagttt gtctgcaaag aagactattt ctggatcata aaattccggt
      541 tgattcagcg tcgacagaga ggcttctccc tgcataatcc gttgattaaa cgccagccac
      601 tgagcggtgg gattaacatg cgaaggtact gattcacgca accttaatat ttcgtccggt
      661 atattctggc tgaacgtagc atttggtata tatgcataat tcatgtggca catatattgt
      721 agtggcatat ctacagaagc cagattggtt acggccatct taatatcgaa caatgtagag
      781 gatctgtgaa ggaccactgt tggctgagcc agataatgat gcccgaaccc cattacatac
      841 tcgtaacgcc cggtaaggcg taacatatct ccctctaatt ccatccatgc ttcatccatc
      901 gcggcacagg ccatttcacc gtgtagcaga tgagtatctt ccgcagatgg gcagccatta
      961 gccagcaaac ctgaatgaaa ggcaaaacag ccataggttt ctatcacctc tgtcgccggt
     1021 ttaggctggc gaaacatatt gcacatggtg agactgtgtc catcaaattg cgcatcccaa
     1081 atcatctgcc ccatccaggg aagaataatt aaatgtccac gactgtttgc aattttaagc
     1141 ccctcgacac cactgtcata gcgaaaagac gtgacagtaa aatcactatt ttccagcaag
     1201 atacgaggtt tttcgccaaa aagcgcccgc cacaaataaa tacgcgtact cataacgatt
     1261 ctcctcagga ctctgtgact tcagccagtg cattacgtac tttgctttca cgccagaagt
     1321 agacaccgac atagacaaaa cagagcatag aaaccaggaa tgaaagctgt agtgagtgga
     1381 acatatctgc aatatacccc tgaattgccg gaaccaccgc tgcgccaaca atagccataa
     1441 caatgactgc tcctgccatt tctgtatgtt gattatcaac tgtatccagt gttcctgcat
     1501 agatcgtcgc ccagcaaggg ccaaacaaaa cacttaccag gacggcgaca tagaccgcgc
     1561 tgaaacttgg agccagtgca acatatgcca gaaacagcgc ccctataacg gaatagagaa
     1621 ttaggacttt ttccggatta aaacgtgtca taaggatgtt ggctataaac ttgccaataa
     1681 agaagcaggc aaagctgtag accatgaagt ttgaagcatc acgttcgttg atatcgccca
     1741 actccagtgc cagacggatg gtaaatgacc atactgcgac ctgcataccc acataaagga
     1801 attgagccac aataccacga cgaaagcgcg aatttttagc cagatagcgc agcgtatcca
     1861 ttgctgacgg gcgtttatgg tgacttgtct gtgccacttt acaggttggg aagcgggtta
     1921 aaaggaacaa caccatgacc acaaccagaa tcataatcat atacttatac ggttcaaggg
     1981 tgttctctaa catcagcacc ttaaagttgt gaatttgctc ggcgttcatt ccggacatct
     2041 gcttctcaag gctttccccc tcggagaaaa ccagatattt gcccaataaa ataccagacg
     2101 cagcaccaat cggataaaag gtctggctga tattgagccg caatgtggca taggcttttg
     2161 gaccgatcat tgaactgtat gtgttcgctg cagtttcaag gaaactcagg ccaatcgcaa
     2221 tcgcaaaaat agctgcaagg aacatagtgt aggttgccat atgcgaggca gggaaaaaaa
     2281 gtgtacaacc accaatatac agcgtcaggc caattaaaat tgccacctta taactggtct
     2341 ttttaatcac aagggatgct ggtattgcaa ttaaaaaata acctccataa aatgcgctct
     2401 gcaccaatgc tgaagcaaag ttacttagcg aaaatacact tttgaattga gtgattaata
     2461 tgtcatttaa tgcagctgcg catccccata gcgggaataa acacgataac aaaataaact
     2521 ggaacaaggg agtcttattc agatacccat caggcatctg aatgatgttt ttatcgttca
     2581 tagtgctacc tttaactgtg caggatgatt attcgtttaa ggttaaaaat tcattaaatt
     2641 gttcaatact cggataagat gattgcgtac ctttccctgt gacgctgaaa gcggcaaaga
     2701 gagcggcttt tttcaaagcg gcttcaacat caccgctttg aacataataa tgggaaaagc
     2761 aaccaataaa tgcgtcacca gcgccactag tatcaacagc atttactttg aatgcaggaa
     2821 catggacttc ctgatcgcgg gtcatccata atgcgccttt ttcgctcatg gtaacaataa
     2881 tattgttcag ccctttatca actaacgaac gtgcggccaa acgaatatga tcataagtat
     2941 caaccgacat accggttaat atttccagtt ctgtttcatt cgggataaag aaatcacatt
     3001 tgcaggcata agacatatct aactcacgca atgccggagc cggatttaat aacacttcaa
     3061 taccattttt cttaccaaac tcaatcgcgt ggtaaactgt ttccagttga acttccagtt
     3121 gtaaaacgat caatttgcat tttttcagat cttctgcagc tcgatcgata tcttccgggg
     3181 aaagaaattt attcgctccc ttaattatta atatactatt gctcgagttg gcattaacaa
     3241 agatcggtgc aacaccactg ctggtacagg ggaccttctc aacataagtg gtattaattc
     3301 cccatgattc aagattacga atagtattat ccgcaaaaat atcatcacct actttagtca
     3361 gcatcaggac ttttgaattc aatttagccg ccgccaccgc ttgattagca cctttcccac
     3421 cacatccgat tttgaaggca ggtgcttcca gagtttctcc ttctttaggc atctgattag
     3481 tgtaagtaat gagatccacc atattggaac caataactgc aatgtccatt tcactacctc
     3541 ttataaactt tcgcataaca atggtattta aataacatta gcatgttact tttgcatcat
     3601 ttgtgactga gatcgcgatt agcacatcaa cccgatgttt atttaataga cttccagtct
     3661 catcactcag gccaacacta tctaatcata agcaacctaa caagattagt gcccaaaact
     3721 cagcagccta tacccttttc atttcaaagg ggcggtcgta tagtatggta atgaaaacaa
     3781 tgtttactaa cgccaaaatg ttatttttat aacattctta cggagagaga gttgatggaa
     3841 acgaagcaaa aagagcgtat ccgacgtttg atggaactgc ttaagaaaac cgacagaatc
     3901 catttgaaag acgcagcgcg aatgctggaa gtttctgtaa tgactattcg tcgcgatctc
     3961 catcaggaag atgaacctct gccactgacc ctactgggtg gctatattgt aatggtgaat
     4021 aaacccgcgc catccatgcc agtaatccat gacgttccaa aaaatcatcg tgatgactta
     4081 cctattgcaa ttctggctgc cggaatggtt aatgaaaatg atctgatctt ctttgataat
     4141 ggccaggaga taccactcgt tataagcatg attccggatg caatcacctt caccggcatc
     4201 tgttactcac atcgcgtctt tgttgcgttg aatgaaaagc ctaatgtaac agcaatactt
     4261 tgtggtggta cgtatcgtgc cagaagtgat gctttttacg atgccagtaa ctcttcgcca
     4321 ttagactctc tcaatccgcg aaaaatattt atttccgcca gcggtgtgca taatcacttt
     4381 ggcgtcagct ggtttaaccc tgaagatctt gccactaagc gtaaagcgat gaaccgtgga
     4441 ctacggaaaa ttttgctcgc ccgccacgcg ttgttcgatg aagtggcctc tgccagcctc
     4501 gcaccgatct ctgcatttga cgttctgatt agcgatcgtc cgttaccggc agattatgtt
     4561 acgcactgcc agaatggttc tgtaaagatc attacacctg attcagaaga cgaatgactt
     4621 actgaaaaaa caccacaatc ttgttaaaca tcgtcgggtt ggactgatta cgttgcactt
     4681 tcaccacata ttccagctta tctatttggc ttatcaccta ctccagacgc tggtcatcct
     4741 tgaccagtag ccagatatgg cttttgtcgc agtcctgaat cggcaggcag agaatgtctt
     4801 caacgttaag agcgcgacgg gcaaaagccc acaaaggtga gtcattacac ccggatggta
     4861 aacaggcact tccttgttgt agaagccgtt atattgtcca taatgtatgg gtttttaatg
     4921 catactgggt aacaaccgga cgaatcttcg aatatcactg gcgctgccag ccggtttgaa
     4981 ttcatctcac aaccctgcat agagcgaatc tcctgcctgc acgtcactcc actccatggt
     5041 atcaacttca cactctttat ctgcggctag cttcagccac cagataagca tcgactatga
     5101 aagatgagcc atgacaacat aacgttggta acgctctgac gccttaatgg aagatgcctg
     5161 ccaccatagg gaatgtaaac gactgaagtg tggcctttaa tgccgtgaac ggctcatggt
     5221 ttcctggcac ggttgccgcc ccaacctgta acaacattcc acagtacaat gtctgtcaga
     5281 gtcagagcct cccatgcttg ttgtagtaac tctaccagtt acgaacatcc ttcctcaaaa
     5341 ttgttgtcat atctcgcatg gaagaaaaga tcctggctaa ggagcaacac acaacgtatt
     5401 gcggaacttg catatttttc ctgtaactag tgtattacca catatggtaa tagctacctg
     5461 tgtggtttcg ctggatagca aggggattta ttcgcaagta aaatgcctga taaaatacac
     5521 gaatctagta atcatcaata tttactctgg tcgaatgacg cgtgaagtgg acggccaaca
     5581 gacgcagtca gtgatctaca gcctgttgaa taaaaccccg gatgcttccc ccgattactg
     5641 caagtaatac ttcggttatt tgcactattt tatccctgtt gaatttggtt aagccggtgc
     5701 agacgcgccg ggaaacgcac acctgaaccg gcacaataaa atacaataca atacaacccc
     5761 ctgttactgg agaaatgcct gcgccggggt ccgatatggc agtattgttg cagcctgcgg
     5821 catggctcag gggatggatt tgatgggcaa tatggctccg tttattctgc gtggtgtcac
     5881 gctgaaaggg attgatagcg tcatgttcgc gaaagagaaa agagcagcaa tctggcaaca
     5941 ggcggtatag tatttgccag agtccagaat ggatagtctc actaccgttt atccgctcag
     6001 tgacgccatc actgtggctg aaaaacttct gagtggcgga attcgcggtc gtgcagtcat
     6061 tcaatatagc taattagatg gatgccgagc tcaggcttag tataataagt tttaggggct
     6121 gcggcccctt ttactggcca gttgttgctt cctgagaaga ctgatagcgt accgaggttt
     6181 tgaaatagct ccagaagtcg tacactggct cagtagaaca atatagtttg gaacgcatta
     6241 ccgcaccttc ccagccactc cagaaaatag ccgccagttg tgtattattc atatttgaac
     6301 ttatttcgcc tgaagataac gcgtcggaca ggcaggccgc aacaagtgcc tgccagctct
     6361 caagaatatt ctgtagtact ttaatgaagg attggggaag ccccggactc tcctgcatca
     6421 tatttccaac caggcagccg cgggtaaaat tgtatttttt aatcccctca caggcatcat
     6481 tgatgaaatt ttccagacgt accattggtg tgcaggatga ttcatgtaga tgttttttga
     6541 gtttatgctc gaagaaactg tcataggcgt tcagaacggt ctgagcataa tcctctttac
     6601 tcttaaagta gtaataaaat gagcctttag ggacattggc atttttaaca atggcatcga
     6661 ctcccgtcgc aagaaaacca ttctgcgtca gcagttcaag gccactgcgg atcagatcat
     6721 tacgagtatc tgcataggta ctttctgtct ttcgcggcct tccccggcca cgattttcgc
     6781 ctgtcatgac ccatctccta cattttatta acgcaaaaga ataagtgatt ttgcgcgaga
     6841 gcttcaatca gtttatcccc gcagtggcaa agtgttcgct tttgccgact ggacagtggc
     6901 agtgcctgtc gctactgcgc catcgctgaa cagtgcagaa ttagcaacgt ttgcttttgg
     6961 cacaaagcat acgcccattc tcacgcgaat gctttgccct tgacttgcca acaaccgaat
     7021 tgcttgctct gcagctatgt tt
//
LOCUS       DAFGPF010000190         6924 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFGPF010000190 DAFGPF010000000
VERSION     DAFGPF010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6924
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.190"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(131..403)
                     /locus_tag="LSX49_004884"
     CDS             complement(131..403)
                     /locus_tag="LSX49_004884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HBL7171153.1"
                     /translation="MKMMRMYCPTCQAVARIGKTNRKHPQLYDVYCYCSNVECGHSFV
                     MNVAFSHSVSPSALNGQGRVKELIDAIPPEEREKALKLLLAAQKNG"
     gene            complement(686..3373)
                     /locus_tag="LSX49_004885"
     CDS             complement(686..3373)
                     /locus_tag="LSX49_004885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBL7171154.1"
                     /translation="MKTPSVSTISGAAIGRWPYILSALGIKVPSAGHHGACPACGGKD
                     RFRLDDKAGRGTWFCNQCGHGDGLDLVRLVTGRKIKEVAGMVSEALALPEIQEKPALP
                     ARKKAAGKEAGAERYTRLRQQSCNGEPVYLTNKSLHGYSLPLLSQPLNLAGITFSTGS
                     LLLPLTDISGNITGGQLINPDGDKSLLPGSQLSGAFIALTDIPAETPEQVIITEGFAT
                     ALTVSLLTEGWIVAAVAATNLLKVTEQIRKRWPETRIILAGDNDLADGKENTGRIQAE
                     KAAKAVDGWVTLPPVRHKADWDDYRQEVGKERARDAFREEMTLHGKGQTRLPEGFRLT
                     KEYLWYDKLVNKSDGDTEIRNIKICSPLRVTAITSDADGSNYGRLLEWEDTNGNSRKW
                     AMPMEMLGGSGEELRRVLLVNGLSYININGMARAFLMEYISLCKPDRKVTCVNKTGWH
                     GGVYVLQDEVIGREAQSVILQTSSVQGRDFRVSGTSEGWRENIGRYCIKNARLAFAVS
                     LAFAAPLLKLVGIGGGGYHLKGESTDGKTTTMKVAASVCGGTDFWHTWRATGNALEGT
                     ASRRNDATLMLDEIREVDGREAGNIAYMLANGQGKARARTDGSVRETNRWNLLFLSTG
                     ELSLVEHAASAGERTYAGVEVRMIQIPSDSGKYGVFEELHGFSSGKTLAEHLEQHVAH
                     YHGAPFRDWLYCLTADLPELTSQAKALLKEYTRRLTPENAGNQVGRAVTRFALVAMAG
                     ELATKAGITGWPEGEAFRAAQSCLAAWMADRGHTANQEDKAALEQVRDFMTRNQFSRF
                     ADWNDDRNRPVSMMGFRKVDKGDNVTEPVVTFYVLPSGWKEICKGFDSRKVARLCVDA
                     GWLKPGEDGRTQNSIRLPEIGLKRVYQFNTQVLGSAEPE"
     gene            complement(3370..3780)
                     /locus_tag="LSX49_004886"
     CDS             complement(3370..3780)
                     /locus_tag="LSX49_004886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171155.1"
                     /translation="MNNNQNLKAHALRTAVLRYYIADAFISLMVRVHNEPVYIEDGER
                     IELSHEKVVSNIIYHIEMPWVNEFGADAGCILAAEKLEKMLKPGFMSENIRLSVFGVT
                     EMREVYRDIIFGAPDGELPEGFEFVKPEGQEVLL"
     gene            complement(3773..4009)
                     /locus_tag="LSX49_004887"
     CDS             complement(3773..4009)
                     /locus_tag="LSX49_004887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171156.1"
                     /translation="MKSMNFKQGCILSEQGESRLLRAALASEFLAEVLSVPTVNGART
                     VSAEGAAALVACIAEQLDGVVKETSTIKGVMRDE"
     gene            complement(4006..4596)
                     /locus_tag="LSX49_004888"
     CDS             complement(4006..4596)
                     /locus_tag="LSX49_004888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HBL7171157.1"
                     /translation="MPALINPGNDQFSVINFLPHQECAGYSLKVAAKSAAGRRNPCYL
                     KAILHALGVFFCVAALTHLKFMVWWLIVFFYFLRHIIRIMVVQAGQLSGWPVSFRAGI
                     PTPVWATTHERRNSGGSVTRYLKEVAIMATVPALSHPEFTFVFLAVRRTDRDARPRPV
                     RVIAECEHAARLKLATEFILSFAARIPVKRAGEVVA"
     gene            complement(4684..5688)
                     /locus_tag="LSX49_004889"
     CDS             complement(4684..5688)
                     /locus_tag="LSX49_004889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006762596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P2 family phage major capsid protein"
                     /protein_id="HBL7171158.1"
                     /translation="MYAFKTERPDAARRYHNKFVTGTNYQEESNRRFALSEPTENILR
                     TSILESGWLIKNITLRDVNAVSGNAVNIGASELYTGRVDGGRFHKKMAINGTEFFLTE
                     TDTCARISYSDMSHIYHTGVPDEFEKTVESFFAQAYALDMLRVGFNGVSIANTTNPEI
                     NKKGEDVNIGWHALAKAYGNGKQIISEPVTLGETGTWKNIDALANHLITELIAEQFRE
                     DPRLVVLVGAELAAHQRLKLFNAADRPSDVNAAQMATSSVAGRFAFIPPFMPGKRLAV
                     TTLDNLHIYTQAITRWFRAEFDDESSEYVHSYLRNEGYALGEPELYAAVDECTLTFAD
                     "
     gene            complement(5711..6571)
                     /locus_tag="LSX49_004890"
     CDS             complement(5711..6571)
                     /locus_tag="LSX49_004890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171159.1"
                     /translation="MVDNVFKKKLASIKNEHVSVLDSYKVRSFKETHSDTACIVRIIE
                     IYSLNKLRAKGEKLYSLTGLTVPDTETVANEINLLLSRYAQLCRQEEEELSFRQREVT
                     NAEVAWKSTFSKNGVSSIAEAKTNKMGHAERADAERYYHLAVSRLNEQHSRLSTIKLL
                     PGVLADEGNYIGKGIDKRLLNIFPQSGQIPADFISVFNDSDVVRDIKFITDALKSLSD
                     SVSEIISRCSVPTDRYVLNNGGMARAMAYREYYRADNYVLRSVVSDRDYVEHVMKYNL
                     VTEYKNKIFS"
     gene            complement(6589..6816)
                     /locus_tag="LSX49_004891"
     CDS             complement(6589..6816)
                     /locus_tag="LSX49_004891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBL7171160.1"
                     /translation="MSLLPRENAPQKRYRLLRISEVINLTGLPKSTIYLKIKNDEFPN
                     QVSIGSRSVAWVEHEVNEWIEKNILNRKLNS"
BASE COUNT         1741 a         1879 c         1443 g         1861 t
ORIGIN      
        1 tgtgtgattt tatgaaggtt tgtgaaacat gaagaagata accagttgaa aaataataat
       61 tttatgaccg tataaactga aatcctgtgt tcaggttccg ggaacagatc ggccattccc
      121 gacgcatact ttacccattc ttttgcgcag ccagcagcaa ctttaaagcc ttttcccgtt
      181 cctcgggtgg aattgcatca atcagctctt taacccttcc ctgcccgttc agcgcgcttg
      241 gactaacgga atgggagaaa gcaacattca tcacaaacga gtgaccgcac tccacattag
      301 agcaatagca gtacacatcg tacagttgtg ggtgtttcct gtttgtttta cctatccgtg
      361 ctactgcctg acatgtgggg cagtacattc tcatcatctt catcgttctg tgccctatac
      421 tgttgcccgc cagaagaagg gatttggatc cctacctctt gttctgaacg tgtaacactg
      481 gtaacacgtg taacgctatt gatttaaaag gatttaatct gttaccagtt agcaaaatca
      541 agaggtaacg cgtggtaaca caccattttt tgttacctct gttaccagtc agtatttttg
      601 actggtaaca ctgaagaacc gcatcagtaa cgggtgttac ctctgttacc agtgttacct
      661 cataaaaata agactcacgc gataatcact caggttcagc gcttcccagt acctgtgtat
      721 tgaactggta cacacgttta agccctattt ctggcaggcg aatgctgttt tgcgtccggc
      781 catcttcacc gggtttcagc cagcccgcgt ccacacacaa cctggccacc ttacgcgagt
      841 caaatccctt acagatctcc ttccagcctg acgggagaac gtagaacgtc acaaccggct
      901 ctgtcacgtt gtctccttta tcgacttttc tgaatcccat cattgaaaca ggccggttcc
      961 tgtcgtcatt ccagtcagca aaccgactga actgattacg cgtcatgaag tcccgaacct
     1021 gttcaagtgc cgctttatct tcctgattag ctgtatggcc ccggtcagcc atccatgcag
     1081 ccagacagct ttgagcggca cgaaaggcct ctccctccgg ccatcctgtg atgcccgctt
     1141 ttgtggccag ctccccggcc atcgcaacca gagcaaaacg ggtaacagcc cggccaacct
     1201 gattcccggc attttccggc gtcagccttc gggtatactc tttcaataag gctttcgcct
     1261 gactggtcag ttccggcaga tcagcggtca ggcaatacag ccagtcgcgg aatggtgcac
     1321 catgataatg cgctacgtgc tgctcaagat gctcagccag ggttttcccg ctactgaagc
     1381 catgaagttc ttcaaacacg ccatacttgc ccgaatcgct tgggatctgg atcattctga
     1441 cctcaacccc ggcatacgta cgttccccgg cgcttgccgc atgctctacc agtgacagtt
     1501 ccccggtaga cagaaacaac agattccagc ggttggtttc ccttaccgaa ccatctgttc
     1561 tggctctggc tttgccctgc ccgttagcca gcatataagc gatatttccc gcctccctgc
     1621 cgtcaacctc ccggatttca tccagcatca gcgtggcatc attgcggcgg ctcgccgttc
     1681 cttctaaggc attccccgtc gcccgccacg tatgccagaa atctgttcca ccacatactg
     1741 atgcagccac tttcatcgtc gtggttttac cgtctgtgga ttcccctttg aggtgataac
     1801 ctccaccgcc gataccaacc agtttcagaa ggggggcagc aaatgccaga ctcaccgcaa
     1861 aggcaagacg ggcattcttt atgcaataac ggcctatatt ttcacgccag ccctctgatg
     1921 tgccgctgac acgaaaatca cgcccctgca cactcgatgt ttgtaagatg actgactggg
     1981 cttcgcgccc tatcacttca tcctggagaa cgtaaacccc gccgtgccag ccagttttat
     2041 tcacacaggt tacttttctg tccggtttac acagcgagat atattccatc aggaatgctc
     2101 tggccatgcc gttaatgttg atgtaagaaa gcccgttaac cagcagaacg cggcgcagtt
     2161 cttccccgct accgcccagc atctccatcg gcattgccca tttacggctg tttccgttgg
     2221 tatcttccca ttccagcaaa cgcccgtaat tacttccatc agcatcactg gtgattgccg
     2281 tcacccgcaa cggactgcaa attttgatat tacgtatctc tgtatcacca tcagacttat
     2341 taaccagctt gtcgtaccac aaatattctt ttgtcagccg gaacccttct ggtaaacggg
     2401 tctgcccttt gccatgcagc gtcatttctt cacgaaaggc atctctcgcc cgttctttcc
     2461 ccacttcctg ccgataatca tcccagtcag ccttatggcg taccggaggg agcgttaccc
     2521 agccatccac cgctttggcg gctttctctg cctgaatacg cccggtgttt tctttgccgt
     2581 cagccagatc attatctccg gccagaatga tccgggtttc cggccagcgt tttcggatct
     2641 gctccgtcac cttcagtaaa ttggtggcag cgacagccgc cacgatccat ccttcagtca
     2701 gcagactgac ggtaagcgcc gtggcaaaac cctcagtgat aatcacctgt tcaggtgttt
     2761 cagcgggtat atcggtcagg gcaatgaatg cgccagacag ctggctaccg ggcagcagac
     2821 ttttatcccc gtcaggattg ataagctggc caccagtaat attcccggaa atatccgtca
     2881 aaggcagcag taatgaaccg gtggaaaatg ttattccggc cagattcaaa ggctgtgaca
     2941 gcaagggaag tgaatacccg tgtaagctct tatttgtcag atagaccggc tcaccattgc
     3001 aggactgctg tctgagtctg gtatatcgct ccgcgcccgc ttcttttcct gcggcctttt
     3061 tcctggctgg caatgcgggc ttctcctgta tttctggtaa tgcaagcgcc tcagatacca
     3121 tcccggcgac ttcttttatc tttcttcctg tcaccagacg aaccagatca agaccatcgc
     3181 catgaccgca ctgattacaa aaccacgtcc ctcgccccgc tttatcgtcc agtcgaaaac
     3241 gatcttttcc accacaggca gggcaagccc catgatgtcc tgcggacggt actttaatac
     3301 ctaatgctga caggatataa ggccagcgcc caattgcagc tccggaaatc gtggatacag
     3361 acggtgtttt cacagcagca cctcctgacc ttccggcttc acaaattcaa aaccttcggg
     3421 tagttcgcca tcaggtgctc cgaaaataat atcccggtaa acctcacgca tctctgtgac
     3481 accaaaaact gacaggcgaa tattttctga cataaagcct ggtttaagca ttttttccag
     3541 tttctctgcg gccagtatgc aaccagcatc agccccaaac tcattcaccc acggcatttc
     3601 aatatggtaa ataatattac tcaccacttt ttcgtgggag agttctattc gttcgccatc
     3661 ttcaatataa acaggttcat tatgaacacg caccattaag gaaatgaatg catcagcaat
     3721 gtagtagcgt aagactgctg ttcgtaaagc atgcgccttt aaattttgat tattattcat
     3781 cgcgcatcac tcccttaatt gtgctggttt ccttaacaac gccatccagt tgttcggcaa
     3841 tacaggccac taaagccgca gcgccttccg ctgaaacagt tctcgctcca ttcactgtgg
     3901 gcacggacaa gacctctgca agaaactcac tggccagtgc cgcccgtaac agacgactct
     3961 ccccctgttc actcaatatg cagccttgct taaaattcat ggatttcatg caaccacctc
     4021 cccggctctt ttcacaggga tacgggcagc aaagctcagg ataaattcag tggcaagttt
     4081 aaggcgtgca gcatgctcgc attctgcgat tacacgcaca gggcgtggac gggcatcacg
     4141 gtctgtacgg cggacagcca gaaagacaaa ggtaaattca gggtgagata aagcagggac
     4201 tgtagccata atggcaacct ccttcagata gcgggtaacg ctaccaccgg agttcctacg
     4261 ctcatgggtg gtagcccaga cgggggtagg aataccggct ctgaaggata ccggccagcc
     4321 cgaaagctgc cccgcctgga ctaccataat tctgatgatg tggcgtaaaa aataaaaaaa
     4381 tacaatcagc caccacacca taaattttag gtgagtcaaa gctgcgacac aaaaaaacac
     4441 gcctagcgcg tgtagtatcg ccttcagata acacgggttc ctacgcccgg ctgccgattt
     4501 tgcggcaacc tttaaactat atcccgcgca ttcctggtga ggcaagaaat ttataaccga
     4561 aaactgatca ttgcctggat taattaacgc tggcatgctt aagcctctgc ttaaaaatag
     4621 ttcttcattt ttcctgatgc tgtaaacgag acccgcctct gagcgggtct ttctgtcgct
     4681 aagtcaatcc gcaaacgtca gggtgcactc atcaacagcc gcgtacagtt caggttcacc
     4741 gagtgcataa ccttcattgc gcaggtagga atgcacgtat tcactgcttt catcatcaaa
     4801 ctcagcacga aaccagcgtg ttatcgcctg agtgtaaata tgcagattat ccagcgtcgt
     4861 tactgccaga cgcttacccg gcataaacgg gggaataaac gcaaagcggc cagcaacaga
     4921 acttgtagcc atctgtgccg cattcacatc agacgggcgg tctgcggcat taaataactt
     4981 caggcgttga tgtgctgcca gctctgcccc aaccagtaca accagacgag gatcttcacg
     5041 aaactgctca gcaataagct ctgtaatcag atggttggcc agagcatcaa tatttttcca
     5101 ggtgccagtc tctcccagag tgacaggctc agagatgatt tgctttccgt tcccgtaggc
     5161 tttcgccagt gcatgccagc caatattgac atcctcgcct tttttattga tttccgggtt
     5221 tgtagtattt gcaatcgaca caccgttgaa accgacccgc agcatgtcca gcgcatatgc
     5281 ctgggcaaaa aagctctcaa ccgttttctc aaactcatcc ggcacgccgg tatggtaaat
     5341 atgagacata tcggaatagc tgatccgggc gcaggtatcc gtctctgtca gaaagaactc
     5401 cgtaccattg attgccattt ttttgtggaa acggccacca tccacacgtc cggtatacag
     5461 ttcactggca ccaatattga cggcattacc tgacacggcg ttaacatcac gtagggtaat
     5521 atttttaata agccacccgg attccagaat tgaggtacgc agtatatttt cagtaggttc
     5581 gcttaatgca aagcgtctgt ttgattcttc ctgatagtta gtgccagtga cgaatttatt
     5641 atgataacga cgtgctgcgt ccggcctttc agttttgaag gcatacatag tttttcacct
     5701 ttttaagtat ttaagaaaag attttatttt tgtactcagt aaccagattg tatttcatta
     5761 catgctcaac ataatcccgg tcacttacga ctgaacgtaa tacataatta tctgctcgat
     5821 agtactccct gtaagccata gctcttgcca ttccaccgtt atttaataca taacgatcag
     5881 ttggaacgct acaacgacta ataatttcac tcacggaatc agataaagac ttgagtgcat
     5941 cagtaataaa tttaatatca cggacaacgt cactgtcatt aaatacagaa ataaaatcag
     6001 cagggatctg gccggattga ggaaatatat tcagtaaacg cttatcgatt cccttcccaa
     6061 tgtagtttcc ttcatcggcc agtactcccg gcaaaagctt gatcgtgctc aatcgactat
     6121 gttgttcatt caaccgggaa acagccagat ggtaataccg ttcagcatcc gctcgttcag
     6181 catgccccat tttattcgtt ttggcttcag caatgctact gacgccgttt tttgagaatg
     6241 tgcttttcca tgcaacttcc gcatttgtca cttcacgctg ccggaaagat aactcttcct
     6301 cttcctgacg acacaactgg gcataacggc tcaggagcag gttgatctca ttcgccacag
     6361 tttccgtatc aggtactgtt aaccccgtaa gtgaatacag cttttcacct ttagctcgca
     6421 gcttattcag tgaatatatt tcaataatac gcacaataca ggccgtgtcg ctatgagtct
     6481 ctttaaatga tcttactttg taactatcta acaccgacac atgttcgttc ttaattgatg
     6541 ccaatttctt cttaaaaaca ttgtcaacca tatatttgcc acctcaattt aggagtttaa
     6601 ttttctattg agaatattct tctctatcca ttcattaact tcatgctcca cccatgcaac
     6661 agaacgagaa ccgatagaaa cttggttcgg aaattcatca ttctttatct ttagataaat
     6721 tgttgacttg ggtaagccag tcaaattaat cacttctgat attctcagaa gtctatatct
     6781 tttttggggt gcgttttccc gaggcaataa gctcatggct atgtccttca cattagatat
     6841 ttatactaag acttaattag tctctattgg gtgtatatat acttgcacag aagaattaat
     6901 acgtaaagac tggcactttc aaac
//
LOCUS       DAFGPF010000191         6908 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFGPF010000191 DAFGPF010000000
VERSION     DAFGPF010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6908
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.191"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            37..1023
                     /locus_tag="LSX49_004892"
     CDS             37..1023
                     /locus_tag="LSX49_004892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBL7171161.1"
                     /translation="MSELIATAASSINAFTLAKRVAAFNVPVLIQGETGAGKECVAKY
                     IHTVAFGENDNAPYIGVNCAAIPENMLEATLFGYDKGAFTGAIASVPGKMELANNGTL
                     LLDEIGDMPLALQAKILRVLQEQQVERLGSNRQIKLNFRLIACTNKNLEQDVAAGRFR
                     EDLYYRLAVIPITMPPLRERLNDIIPLAESFIKKYATVLVKNITLSESTRRALLNYRW
                     PGNVRQLENAIQRGMILNRDGVIYPDALGLPETDIADHSELQWPVQPAVHIAETRDLG
                     QHGRSAQYQYIADLMRKYQGNRSKIADLLGITPRALRYRLASMRKQGIEVFS"
     gene            1038..1379
                     /locus_tag="LSX49_004893"
     CDS             1038..1379
                     /locus_tag="LSX49_004893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBL7171162.1"
                     /translation="MSITTINSTMQAQIMQDVQRMQANAQAPVLPSMTFSSTDPDVSF
                     NRIMYGALGHVDQFQQVAEQQQTAVDTGKSDDLAGAMIASQQASLSFSALVQVRNKIA
                     TGFNDLMSMSI"
     gene            1384..3030
                     /gene="fliF"
                     /locus_tag="LSX49_004894"
     CDS             1384..3030
                     /gene="fliF"
                     /locus_tag="LSX49_004894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001643010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBL7171163.1"
                     /translation="MNAQIKKLTQAFPAFRLHLVDNKRWVLMAGVGLAVAVTAIIVSV
                     LWTGNRGYVSLYGRQENLPVSQIVTVLDGEKLTYRIDPQSGQILVPEDALSKTRMTLA
                     AKGVQAILPSGYELMDKDEVLGSSQFVQNVRYKRSLEGELAQSIMSLDAVESARVHLA
                     LNEESSFVVSDEPQNSASVVVRLHYGAKLNMDQVNAIVHLVSGSIPGLQASKVSVVDQ
                     AGNLLTDGIGAGEAVSAATRKRDQILKDIQDKTRASVANVLDSLVGTGNYRVSVMPDL
                     DLSTIDETQEHYGDAPKINREESVLDSDTNQVAMGVPGSLSNRPPIAANQMTNGTEEN
                     RSPEALSKHSESKRDYSYDRSVQHIQHPGFAVKRLNVAVVLNQNAPALKNWKPEQTTQ
                     LTALLNNAAGIDAQRGDNLSLSLLNFVPQAVPVEPVIPLWKDDSVLAWVRLIGCGLLA
                     LLLLFFVVRPLMKRLTAVRAPVITPEPEAVSEPWIAMPEEERKNVDLPSLPGDDSLPS
                     QSSGLEVKLEFLQKLAMSDTDRVAEVLRQWITSNERIDNK"
     gene            3008..4018
                     /locus_tag="LSX49_004895"
     CDS             3008..4018
                     /locus_tag="LSX49_004895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBL7171164.1"
                     /translation="MSELTTNKSNSYLEQAAILLLCLGEEAAATVMQKLSREEVVRLS
                     ENMARLSGVKTSMARKVINHFFDEFREQSGINGASRSMLQGILNKALGTEIASSVING
                     IYGDEIRSRMARLQWVEPRQLAMLISEEHLQLQAVFLAFLTPEISAAVLSYLNESVQN
                     EILYRVAKLNDVNRDVVDELDRLIERGLSVLSEHGSKVKGIKQAADIVNRFQGNQQVI
                     LDQMRERDEEVLGQIQDEMYDFFILSRQNEEVRRRLLDEVPMEDWAVALKGTEALLRR
                     SIYAVMPKRQAQQLEAITARLGPVPVSRIEQIRREIMGIARELEEAGEIQLQLFAERT
                     AE"
     gene            4022..4732
                     /locus_tag="LSX49_004896"
     CDS             4022..4732
                     /locus_tag="LSX49_004896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein H"
                     /protein_id="HBL7171165.1"
                     /translation="MTIETLRGRYRLHRFPPRQRAVTGEPLTASISAADYQRQLMDGF
                     QEGLQKGFAQGMTEGQEQGFSEGHQQGFAEGRRQGYTEGSLAGQQEGRKQFVEAAQPL
                     EAITGKVNDFLAHIERKQREDLLQLVEKVTRQVIRCELALQPTQLLALVEEALAAFPT
                     MPETLQVMLSTEEFNRLRDAVPEKVSEWGLTPSPDLPPGECRVITDKSELDIGCEHRL
                     EQCMTALQETLTPESQGE"
     gene            4725..6065
                     /gene="fliI"
                     /locus_tag="LSX49_004897"
     CDS             4725..6065
                     /gene="fliI"
                     /locus_tag="LSX49_004897"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBL7171166.1"
                     /translation="MSDFSAFDNALRSLESIPLARVAGRLVRLNGILLESVGCPLMTG
                     QLCRIESANHTLIDAQAVGFNRDITYLMPFKQPVGLMAGARVFPEEKAHDILIGESWL
                     GRVVNGLGEPLDGKGRLNGNDLLPPLPPSVNPLTRRSVDEPLDVGVKAINGLLTIGKG
                     QRVGLMAGSGVGKSVLLGMITRQTKADIVVVGLIGERGREVKEFIDHSLGADGLAKSI
                     VVVAPADESPLMRLKATELCHSIAAWFRDRGHHVLLLVDSLTRYAMAQREIALSLGEP
                     PATKGYPPSAFGMIPKLVESAGNSESSGSMTAIYTVLAEGDDQQDPIVDCARAVLDGH
                     IVLTRKLAEAGHYPAIDIGQSISRCMNQVTRLEHQQSARALKQNYAAYMEIKPLIPLG
                     GYVAGADASVDKAVKMFPAIERFLRQEMREPASLELVQSRLQILFPIAKKAEGQ"
     gene            6068..6502
                     /gene="fliJ"
                     /locus_tag="LSX49_004898"
     CDS             6068..6502
                     /gene="fliJ"
                     /locus_tag="LSX49_004898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBL7171167.1"
                     /translation="MRQIIDTLAQLQRLRDKSVKDKTVELAKQKQICAGYDNNIKALG
                     YLVEKTSAGAAASVESLKNVSGYKGTLRKVIAWQEQEKTLANIKATRMQKNLTAAACE
                     EKVVALTLDDKRREQQESATAKAQKAVDDIAVQCWLRHKLAE"
     gene            6505..6900
                     /locus_tag="LSX49_004899"
     CDS             6505..6900
                     /locus_tag="LSX49_004899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HBL7171168.1"
                     /translation="MKTVITFGTFDVFHVGHLRLLQRARTLGEQLLVGVSSDALNIAK
                     KGRAPVYPQDDRMAIIAGLACVDGVFLEESLEQKAEYLRGYSADILVMGDDWAGKFDD
                     FSCVCEVVYFPRTPSVSTTGIIEVIRGHF"
BASE COUNT         1632 a         1895 c         2061 g         1320 t
ORIGIN      
        1 atcctgtttt ctgtcgctac ttatatcgtt caccctatgt ctgaacttat tgcaactgcc
       61 gcttccagca ttaacgcttt tactctggca aagcgtgtcg ccgcctttaa cgtaccggtg
      121 ctcattcagg gcgaaaccgg cgcggggaaa gagtgcgtgg cgaaatatat tcacaccgta
      181 gcctttggtg aaaatgataa cgcgccctat atcggcgtga actgtgcggc gatcccggaa
      241 aatatgctgg aagcgacctt atttggctac gacaaaggcg catttaccgg cgcaattgcc
      301 agcgtgccag gaaaaatgga actggctaat aacggcacct tattgctcga tgaaattggc
      361 gatatgccgc tggcattaca ggccaaaata ttacgcgtat tgcaggaaca gcaggttgag
      421 cgattaggca gcaatagaca aatcaaactc aattttcgcc tgattgcctg caccaataaa
      481 aatctggaac aggacgtggc tgctggacgt tttcgtgaag atctttatta tcgtctggcg
      541 gttattccta taaccatgcc gccactgcgt gaacgtctga acgatattat tccgctggca
      601 gagtcgttta ttaaaaaata tgccacggtg ctggtgaaaa atatcaccct gtccgaatcc
      661 acacgccggg cgctacttaa ttaccgctgg cccggaaatg ttcgccaact ggaaaacgcc
      721 attcagagag gaatgatctt aaaccgcgac ggcgtgattt acccggatgc cttaggcctg
      781 ccggaaactg acattgccga ccacagcgaa ctgcaatggc ctgttcagcc cgccgtccac
      841 attgccgaaa cccgcgattt aggccagcac ggacgaagtg cgcagtatca atatatcgcc
      901 gacctgatgc gtaaatatca gggcaaccgc agcaaaatcg ccgacctgtt aggcattacc
      961 ccgcgcgcac tgcgctatcg gctggcctcc atgcgcaagc aaggtatcga agttttctcc
     1021 tgacccggaa gttaaaaatg agcattacca caatcaacag caccatgcag gcgcaaatca
     1081 tgcaggacgt gcagcggatg caggccaacg cccaggcgcc ggtgctaccc tccatgacct
     1141 tcagttccac agacccggac gtgtcgttta accgcattat gtacggcgcg cttggtcacg
     1201 ttgatcagtt ccagcaggtg gcggagcagc agcaaacggc tgtcgacacg ggcaaaagtg
     1261 atgacctggc aggtgcgatg atcgccagcc agcaggcgtc gctctctttc tccgcgctgg
     1321 tgcaggtgcg caataaaatc gccaccgggt ttaacgacct gatgagtatg tcgatctaac
     1381 cctatgaatg cacaaataaa gaagttaacc caggcgtttc cggcgtttcg actgcatctc
     1441 gtagataaca aacgctgggt gttgatggcg ggagtggggc ttgccgtggc ggtgacggcg
     1501 attatcgtca gcgtgctgtg gaccggtaat cgcggctacg tttcgctcta cggacgccag
     1561 gaaaatctgc ccgtgtcgca gattgtcacg gtgctggacg gcgaaaagct cacctaccgc
     1621 atcgacccgc agagcgggca gattctggtg ccggaagatg cactgtcgaa aacgcgaatg
     1681 acccttgccg cgaaaggcgt gcaggcgata ttgcccagcg gctacgagct gatggataaa
     1741 gacgaagtgc tcggcagcag tcagttcgtg cagaacgtgc gctataaacg cagtctcgaa
     1801 ggggagctgg cgcagagcat catgtcgctg gacgcggtgg aaagcgcgcg ggtgcatctg
     1861 gcgctcaacg aagaaagctc gtttgtggtc agcgatgagc cgcaaaacag cgcctcggtg
     1921 gtggtgcgct tgcattacgg cgcgaagctg aatatggacc aggtgaacgc cattgtgcat
     1981 ctggtgtccg gcagtattcc ggggctacag gccagcaaag ttagcgtcgt cgatcaggcg
     2041 ggaaatctgc tgaccgacgg cattggcgca ggcgaggcgg tttctgccgc gacccgtaaa
     2101 cgcgatcaga tcctcaaaga tattcaggac aaaacccgtg ccagcgtggc gaacgtgctg
     2161 gattcgctgg ttggcacggg gaattaccgc gtcagtgtga tgccggatct cgacctcagc
     2221 accatcgacg aaacccagga acactacggt gacgcgccga aaatcaaccg cgaagagagc
     2281 gtgctggaca gcgacaccaa tcaggtggcg atgggcgtgc ctggttcgct cagtaaccgt
     2341 ccgccgattg cagcgaatca gatgaccaac ggtacggaag aaaaccgctc gccggaagcg
     2401 ctttccaaac acagcgaaag taagcgcgac tactcttacg accgcagcgt ccagcatatt
     2461 cagcatcccg gcttcgcggt gaaacgcctc aacgtggcgg tggtactcaa tcaaaacgct
     2521 ccggcgctga aaaactggaa gccggagcaa accacgcaac tgaccgcgtt gctgaacaat
     2581 gccgccggga tcgacgccca gcgtggtgac aatctctcct tatcgttact caactttgta
     2641 ccgcaggcgg tgcctgtcga accggttatt ccactgtgga aagatgacag cgtactggcc
     2701 tgggtgcggc tgattggctg cggcctgctg gcgctgttgc tgctgttctt cgtggtgcgt
     2761 ccgttgatga aacggctgac ggcggtacgt gcgccggtta tcacaccaga accggaagcc
     2821 gtcagcgaac cgtggattgc catgccggaa gaggagcgca aaaacgtcga cctgccgtcg
     2881 ctgcccggcg atgacagcct gccgtcacaa agttctggcc tcgaagtgaa actcgagttc
     2941 ctgcaaaaac tggccatgag cgacaccgat cgcgtagccg aagttctcag acaatggatc
     3001 accagcaatg agcgaattga caacaaataa gagcaacagc tacctggaac aggcggcgat
     3061 cctgctgctg tgtctgggcg aagaggcagc ggcgacggtg atgcaaaaac tcagccgcga
     3121 agaagtggtg cgcctgagcg aaaacatggc gcgactttcc ggcgtcaaaa ccagcatggc
     3181 gcgtaaagtg atcaaccact tctttgacga gttccgcgaa cagagcggga tcaacggcgc
     3241 atcgcgatcc atgttgcagg gcattcttaa caaggcgttg ggtaccgaga tcgccagcag
     3301 cgtgatcaac ggcatctatg gcgatgagat tcgctcgcgg atggcgcgcc tgcaatgggt
     3361 ggaaccacgc cagttggcga tgctgatttc cgaagaacat ctgcaattgc aggcggtgtt
     3421 cctcgcgttt ctgacgccgg aaatctcggc agcggtgctc tcttatctca acgaatcggt
     3481 gcaaaacgaa attctctacc gggtggcgaa actcaacgac gtcaaccgcg acgtggtgga
     3541 tgagctggac cgcctgattg aacgtggcct gtcggtactt tcggaacatg gctcgaaggt
     3601 aaaaggcatc aaacaggcgg cggatatcgt caaccgcttc cagggcaatc agcaggtgat
     3661 cctcgaccag atgcgcgaac gcgacgaaga ggtgttgggg cagatccagg atgagatgta
     3721 cgacttcttt atcctcagcc gccagaacga agaagtgcgt cggcgtctgc ttgatgaagt
     3781 gccgatggaa gactgggcgg tggcgctgaa aggcaccgaa gccctgctgc gccgctcgat
     3841 ttacgcggta atgccaaaac gtcaggcgca gcaactggaa gcgatcaccg cgcgtctggg
     3901 tccggtgccg gttagccgta tcgaacagat ccgccgcgaa atcatgggca tcgcccgtga
     3961 gctggaagaa gcgggcgaaa ttcagctaca gctctttgcg gaacggacgg cggagtaatt
     4021 catgaccatt gaaacactgc gcgggcgcta tcgcctgcac cgcttcccgc cgcgccagcg
     4081 tgcggtgacc ggagaaccgc ttactgccag tatcagcgcc gccgattacc agcgtcagtt
     4141 gatggacggt tttcaggaag ggctgcaaaa agggtttgct cagggaatga ccgaaggtca
     4201 ggagcagggc tttagcgaag gtcatcaaca aggttttgcc gaggggcggc gtcagggcta
     4261 caccgaaggc agcctcgccg ggcagcagga aggacgcaaa cagtttgttg aggcggcgca
     4321 gccgctggaa gccatcaccg gtaaagtgaa cgacttcctc gcgcatattg aacgtaaaca
     4381 gcgggaagat ttgctgcaac tggtggagaa agtcacccgt caggtgatcc gctgcgaact
     4441 ggcgctgcaa ccgacgcagt tactggcgct ggtggaagag gcgctggcgg ccttcccgac
     4501 gatgccggag accctgcaag tgatgctgag tacagaagag tttaaccgcc tgcgcgacgc
     4561 ggtgccggaa aaagtcagcg aatgggggct gacgccttcg ccggatctgc cgccaggcga
     4621 atgccgggtg attaccgaca aatctgaact ggacatcggc tgtgagcatc gccttgaaca
     4681 gtgcatgacc gcgctgcaag agacgctaac gccggagtcg cagggtgagt gatttttctg
     4741 ctttcgataa cgccctgcgc tcgctggagt cgatcccgct ggcccgcgtc gccgggcggc
     4801 tggtgcgcct gaacggcatt ctgctggaga gcgtcggctg cccgctaatg accgggcaac
     4861 tgtgccgcat cgaaagcgcc aatcacacac tgatcgacgc gcaggcagtg ggctttaatc
     4921 gcgacatcac ctacttaatg ccgtttaaac agccggtcgg cctgatggca ggcgcacgcg
     4981 tcttcccgga agaaaaagcc cacgacatcc tgattggcga aagctggtta ggccgcgtgg
     5041 ttaacggtct cggcgaaccg ctggatggca aaggccgcct gaacggcaac gaccttctgc
     5101 cgccgctgcc accctcggtc aatcccttaa cccgccgttc agtggacgaa ccgctggacg
     5161 tgggcgtgaa agcgattaac ggcctgctga ccatcggcaa aggccagcgt gtcgggctga
     5221 tggcgggcag cggcgtcggg aaaagcgtgc tgctggggat gatcacccgc cagactaaag
     5281 ccgacatcgt ggtggtcggg ttgattggtg aacgcgggcg cgaagtgaaa gagtttatcg
     5341 accactcgct gggcgcagac gggctagcaa agtctatcgt cgttgtcgcg cctgccgatg
     5401 aatcgccgct gatgcgcctg aaagccaccg aactgtgcca ctccatcgcc gcctggtttc
     5461 gtgaccgcgg gcatcacgtt ttactgctgg tggattccct gacccgctac gccatggcgc
     5521 agcgtgaaat tgctctctca ctcggtgaac cacccgccac caaaggctat ccaccatcgg
     5581 cattcggcat gatccccaaa ctggtcgaga gcgcaggcaa cagcgaaagc tcaggatcga
     5641 tgaccgccat ctacacggtg ctggcggaag gcgacgacca gcaagatcca atagtcgact
     5701 gcgcccgcgc agtgctggac ggacatatcg tattaacccg caaactggcg gaagcggggc
     5761 actatccggc tattgatatc ggccagtcga tcagccgctg catgaaccag gtcacccgcc
     5821 tggaacatca gcaatccgcc cgcgcgttaa agcaaaacta cgccgcctat atggagatca
     5881 aaccgctgat cccgctcggc ggctacgtgg caggcgcgga cgccagcgtc gacaaagcgg
     5941 tgaaaatgtt cccggctatc gagcgatttt tgcgccagga gatgcgcgaa cccgcctccc
     6001 tcgaactggt gcaaagccgc ctgcaaatcc tctttcccat cgccaaaaag gcagaagggc
     6061 aataaccatg cgacaaatca tcgacaccct ggcgcagttg cagcgcctgc gggataaatc
     6121 ggtcaaagac aaaaccgtcg agctggcaaa gcaaaaacag atttgcgctg gctatgataa
     6181 caatatcaaa gcattaggtt accttgtcga gaaaacatct gcgggcgcgg cggcgtcggt
     6241 ggagtcgctg aaaaacgtca gcggctacaa aggcacactg cgcaaggtga tcgcctggca
     6301 agagcaggaa aaaacgctgg ccaacatcaa agctacgcga atgcagaaaa acctgacggc
     6361 ggcggcgtgc gaagagaaag tggtagccct gacgctggac gacaaacgcc gcgagcaaca
     6421 ggaaagcgcc acggcgaaag cgcaaaaagc ggtggatgac atcgccgtcc agtgctggtt
     6481 gcggcacaaa ttagcggagt agccatgaaa acggtcatca ccttcggcac cttcgatgtg
     6541 tttcatgtgg gtcatctgcg ccttttacaa cgcgctcgca cgctgggcga gcagctgctg
     6601 gtcggcgtat catccgatgc cttaaatatc gccaaaaagg gcagggctcc ggtttaccct
     6661 caggatgacc gcatggcgat tatcgccggg ctggcgtgcg tggatggcgt atttctggag
     6721 gagtcgctgg agcagaaagc ggaatatttg cgcgggtaca gtgcggatat tttggtgatg
     6781 ggcgatgact gggcaggtaa gtttgacgat ttctcgtgtg tatgtgaggt ggtctacttt
     6841 ccccgcacgc cgtcggtatc gacgacgggg atcattgagg tgattagggg gcatttctga
     6901 taatatga
//
LOCUS       DAFGPF010000192         6827 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFGPF010000192 DAFGPF010000000
VERSION     DAFGPF010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6827
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.192"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1671
                     /gene="adeD"
                     /locus_tag="LSX49_004900"
     CDS             <1..1671
                     /gene="adeD"
                     /locus_tag="LSX49_004900"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBL7171169.1"
                     /translation="IIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRID
                     ARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWF
                     ARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGV
                     ISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLG
                     MSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQH
                     NVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDA
                     QTLQAEESARLAQSAPPYGNTIDRQPVSASDFALQFTPGKRYRVIEVIHNELITHSRS
                     SVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIG
                     RSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
                     ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE"
     gene            complement(1718..3109)
                     /gene="uhpT"
                     /locus_tag="LSX49_004901"
     CDS             complement(1718..3109)
                     /gene="uhpT"
                     /locus_tag="LSX49_004901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HBL7171170.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNQYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(3247..4566)
                     /gene="uhpC"
                     /locus_tag="LSX49_004902"
     CDS             complement(3247..4566)
                     /gene="uhpC"
                     /locus_tag="LSX49_004902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HBL7171171.1"
                     /translation="MLPFLKAPADAPLMTDKHEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNSAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAASALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVIAIAAGISALLLLPFLNAQTPREA"
     gene            complement(4576..6078)
                     /gene="uhpB"
                     /locus_tag="LSX49_004903"
     CDS             complement(4576..6078)
                     /gene="uhpB"
                     /locus_tag="LSX49_004903"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HBL7171172.1"
                     /translation="MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLMQAVGLTHFSLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQHDERLMLVIE
                     DDGSGLPPDSGQHGFGLTGMRERVTALGGTLTISCLHGTRVSVSLPQRYV"
     gene            complement(6078..6668)
                     /gene="uhpA"
                     /locus_tag="LSX49_004904"
     CDS             complement(6078..6668)
                     /gene="uhpA"
                     /locus_tag="LSX49_004904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HBL7171173.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
BASE COUNT         1724 a         1966 c         1784 g         1353 t
ORIGIN      
        1 attattgata atgtctctat tctcgacctg atcaatggcg gagaaatttc cggcccaatt
       61 gtgattaaag gacgttacat tgccggtgtt ggcgcagaat acgctgatgc tccggctttg
      121 cagcggattg atgcccgcgg cgcaacggcg gtgccagggt ttattgatgc tcacctgcat
      181 attgaatcca gcatgatgac gccggtcacc tttgaaactg ctaccctgcc gcgcggcctg
      241 acgaccgtta tttgcgaccc tcatgaaatc gtcaacgtga tgggagaagc cggattcgcc
      301 tggtttgccc gctgtgccga acaggcaagg caaaaccagt acttacaggt cagctcttgc
      361 gtacccgccc tggaaggctg cgatgttaat ggtgccagtt ttacccttga acagatgctc
      421 gcctggcggg accatccgca ggttaccggc cttgcagaaa tgatggacta ccctggcgta
      481 attagcgggc agaatgcgct gctcgataaa ctggacgcat ttcgccacct gacactggac
      541 ggtcactgcc cgggtttggg tggtaaagaa cttaacgcct atattgctgc gggtattgaa
      601 aactgccacg aaagttatca gttggaagaa ggacgccgga aattgcaact cggcatgtca
      661 ttgatgatcc gtgaagggtc cgcagcccgc aatctcaacg cgctggcacc gttgatcaac
      721 gaatttaaca gcccgcaatg catgctctgt accgatgacc gtaacccgtg ggagatcgcc
      781 catgaaggac acatcgatgc cttaattcgc cgcctgatcg aacaacacaa tgtaccgctg
      841 catgtggcat atcgcgtagc cagctggtcg acggcgcgcc attttggtct gaatcacctc
      901 ggcttactgg cacccggcaa gcaggccgat atcgtcctgt tgagcgatgc gcgtaaggtc
      961 acggtgcagc aggtactggt gaaaggcgag ccgatcgatg cacaaacctt acaggcggaa
     1021 gagtcggcga gactggcaca atccgccccg ccatatggca ataccattga tcgccagcca
     1081 gtttccgcca gtgactttgc cctgcaattt acccccggaa aacgctatcg cgttattgag
     1141 gtaatccata acgaactgat cacgcactcc cgctccagcg tctacagcga aaacggtttt
     1201 gatcgcgatg atgtgtgctt tattgccgtt cttgagcgtt acggacaacg actggctccg
     1261 gcctgtggtt tgctcggcgg ctttggcctg aatgaaggtg cgctggcggc gacggtcagc
     1321 catgacagcc ataatattgt ggtgatcggt cgtagcgcag aagagatggc gctggcggtc
     1381 aatcaggtga ttcaggatgg cggcgggctg tgcgtggtcc gtaacggcca ggtacaaagt
     1441 catctaccgt tgcccattgc cgggctaatg agcaccgaca cggcgcagtc actggcggag
     1501 caaattgacg ccttgaaagc cgccgcccgt gaatgcggtc cgttaccgga tgagccgttt
     1561 attcagatgg cgtttctttc cctgccagtg atccccgcgc tgaaactaac cagtcagggg
     1621 ctgtttgatg gtgagaagtt tgccttcact acgctggaag tcacggaata ataaaaaaaa
     1681 gcccggcgtc atgccgggca aaagtcacca gttacgttta tgccactgtc aactgctgaa
     1741 tttttttctc gcggcggatt ttgcgttctt ccatcaccgc cactatcgcc atcaggcaga
     1801 tacaaccaat cgcggcgata tccagcgcgg cgaaggtgcc tgcccagccg gtaaggccaa
     1861 ataccggcgt cccatcggca atcattccca gacctaactt ggcaaagctg tcaccaatca
     1921 ggtaagcgaa ggtgccttta ataccatcgg cagcgccaat cgctttttta ggtacaaagc
     1981 caacagccgc cacgccaatc aacagttgcg ggccaaagac caggaaaccc aacgcaaaga
     2041 gagaagccag gtagatatat tggttgctgg cgtgttgata cacaccgagc gtggcgataa
     2101 tcagcgccag cgcgatacag gccaccaggc cacggcgacc gttcgccagg tcagagagcc
     2161 agccccacag cagcgtaccg accagcgcac cagcttcaaa cagcgtaaag ccctgaatcg
     2221 ccaccgcttt agagagtttc agttcctgga acgcatacac agttgaccac tggtcgatac
     2281 caatacgcac cacatagagg aaaatgttgg cgaagcacag cagccagatc actttgtttt
     2341 tcagcacata ctcaacaaag atctgccact tggtcatatc ggtagattct gtctctttat
     2401 cctcttcact gatctcctcg ccaaacagct cttcagcttt gccgaggcca taagattccg
     2461 gggagtcgct gccgtaacgc agaccgataa aaccaacaat cagcgcgata atcgacggga
     2521 aaataaacat gccgatgaca tgaccatcga acaggtaatt tgcgccgaac agcgccacac
     2581 ctgctgcgcc tgcaccacca aggttgtgag aaatgttcca gaaaccgagg aatgtcccgc
     2641 gtttacgacg cggcgtccat ttggtgatgg tggagtaact gcatgaaccg ccggtactct
     2701 ggaaaaagcc gctcaaggcg tagaaggcaa tcatcaggaa caggctaacc gagccgctgc
     2761 ccatactggc actgaagccc agcatacaaa tggcagacag gatcagcatg aacggcagga
     2821 attgtttggt gtttttgccg tcggcgtagt aagaaaccag cgttttaccc acgccataag
     2881 tgatggagaa gcccaggccg atcatcccca gctgcgtcat gctcaacccg taggtcgaga
     2941 tcatgtcgtt ctgcgcgatg ttaaagttct tgcgaatcag gtacatcgta aggtagccga
     3001 taaagaccac caggtaggat tgcatgaacg gtttgaacca cattttgcgc cgcacttcga
     3061 gcggaaggtc cagggtcggc ttgcgaacct ggtttaagaa agccagcatg ggttactcct
     3121 gaaatgaata cctgcgtgag gcatgcattg taaaaatcag cagcaaatca ggcctgagat
     3181 agcgtccagg caaaacctgg aaaatttctt agttttgccg gatatgaagt gaaaaggtga
     3241 gatgcatcac gcttctcgcg gtgtctgggc gttcaaaaag ggcagtaaca gcagtgcgga
     3301 aatcccggcg gcgatggcga taaccacaaa aaatccgctc cagtgccagg tatcgagtac
     3361 tttcgccagc ggccaaccag caagcgacgc accaagataa gcaaacaagc cgacaaaccc
     3421 cgtcgccgcc cctgccgcct ctttgtggga acactctgcc gccgccatgc cgattaacat
     3481 ctgcgggcca aagacaaaaa aaccaatggt gaagaagcag gttgcctgca tcacgtagct
     3541 ggcaaatggc atcagccaca gcgagccgac tgaaagcaaa attccggcgg cgaaaatcaa
     3601 attcatcggc ccgcggttgc cgttaaacag tttgtccgaa ccccaacccg ctaccagcgc
     3661 accgataaat ccgcccagtt caaacattgt cactgccgta ttcgccgtga ccagatcgac
     3721 gcccagcgtc tcggacatat acaaattgcc ccagtcgttg atcgccgccc gaaccacata
     3781 gaccagcaca tagcaaaacg aaagcagcca gatatacgga ttcagcaaca catatttggt
     3841 gaggatctct ttacgcgtca gccctgcccc ttcttgttgt tgagcaatct ccagtgcgtc
     3901 gtgccgccat tcaccaactg ccggtaaacc taacgcctgc gggcgatcgc gcagccgcca
     3961 gcagagaaaa atccccacga cgatcgccat acaacccgca atcatcatcc cggcacgcca
     4021 gccgtaatgc agcgcgctcg ctgccatcac aatgggaatg agtgcgccgc cgacgttatg
     4081 cgccgtgttc cataatgccc accaaccgcc gcgctcggta cgagaatacc aggcggttaa
     4141 cagacgcgca cacaccggtg aaccccagcc ctggaaaaag gcgttcaaca cccagagcac
     4201 ggcaaacgcc catagcgacg tcgagaagcc aaacagaatg ttgataatgc ccgtggcaat
     4261 aagccctatc cccataaaat aacgggcatt tgagcgatcg ctgacaatgc cggagacaaa
     4321 cttcgacaca ccgtaggtaa tgtaaaacag ggtcgctaac aggccaatat cgctacggct
     4381 gagcacgccg ttagcaagga tttctggtac ggcggagtta aaacttttac gcgtgaagta
     4441 aaacagcgcg taacccagcc agatggtcag cagaatatgc cgacgccagt agcgatagcg
     4501 ggcatcaatt tcatgtttat cagtcattaa tggcgcatcg gcaggcgctt tcagaaacgg
     4561 caacatcatc gaaccttaga cataacgttg aggtagagaa acgctgacac gcgtgccgtg
     4621 caggcaggag atggtcaatg tgccacccag cgccgttacg cgctcgcgca ttccggtaag
     4681 gccaaaaccg tgttgcccgg aatctggcgg taaaccgctg ccatcgtctt caatcaccag
     4741 cattaaccgc tcatcatgct gccagccttg cagcgtgacc gcgctggcat cggcatgttt
     4801 cacaatgttg ttcaaccctt cctggcagac gcgaaatagc gtcacgcgct ggttttcgct
     4861 taacgctgat tcatcgattc gccattcgag atgactgaca atgccgcgcc cttccagctc
     4921 catttcccgc atcagtgagc ggatggcctg ctccagggtg agatcatcca gctggcgcgg
     4981 acgtaaccgc cctaacaagc ggcgcaccgc gtcgtaaacg cccaacgaca actgttcgat
     5041 gagctgcccg ctctgtttca cgctggcgtt atccgccgcg agccgctgga caatgccagc
     5101 ctgagtacga atagcagtga tggtctgacc gatatcatcg tgcagctctc gcgccacatc
     5161 gcggcgcacg ctctcttcgg tttccagcaa ccgttcagcg agatgctgat tgcgcgccag
     5221 ttccttttgc agcgactggt taagttcacg caaccgctgg atgccagcgc ccagtaacaa
     5281 ccctgtcaga ctttgcacca gcagcgagag caataaatcc accggatgat cgcgccaggt
     5341 ttgactggcg atcagcgcga tggcgttcat caatgtcgca atcagcgctc cttgccaacc
     5401 atagtgccag gccagcgcga taatcggcag cgccagacag aatggcgtaa agcgcgacag
     5461 ttcgtctggc aatcccaact ggagccagag actgataaca aacagcagca agtaccagac
     5521 cagatgtcgc ccgcgccagt tgattggctg agaaaccagt gacgggccga gcggcagcca
     5581 ggtgttattg gcgagatagt gccagaacac cagacatatc ggggccagcg tcaggccgcc
     5641 agttaaagtc agcagcagcg cattccacga ctctttgccg tgccaaagcc agggcaacga
     5701 ctgcaacaac gctgccgccg ttaacgccgc accctgtaac agcaaggtgc gccagtcacg
     5761 ttgatggcga tagcgcgaga tcagcgccac gggcaataac gtcagtaaac taccgatcat
     5821 caataaggag aaatgggtta aaccgaccgc ctgcattagc cagtaaatca gcagccactc
     5881 cgcacccagt agcaccggcc agtatccgcg cgggcattgc agcattagcc ctagccgcag
     5941 gccaaacgga aataacagca ccgccatatc agggcgctca accaggtgca ggctgatact
     6001 ccacaggcaa aaccatgcgg cagagaagat aaaaaagcag gcaataacgg taattaaacg
     6061 ggagaacaac gtcttcatca ccagccatca aacatgcggc gcgccagttc aacgtcgtta
     6121 ctgacgccca gtttttccat cagattggcg cgatggacgt gtactgtttt cggcgacaag
     6181 cccagttcgg cggcaatctc tttcaccgcc attccttgcg ccagtttttc tgccacctgg
     6241 cgttcgcgtt tggttagcgg gtcctggcga ccagatgcca gtttaatggc aatatccggc
     6301 gtcagataac agccgccagt ggcaaccgta tgcaccgcag caatgagttc atccgggcta
     6361 cagcgtttgg agagaaagcc gcgcgccccc gcgttaagcg cctgctcaac cagcgccgga
     6421 ctgtcgtgaa cggagagcat aattgtcgcc atgcctttcg gcagctggct tagaagctcc
     6481 agaccggaga tatcaggcat ggagatatcg caaatacaca cctgcacacc gcgccccggc
     6541 agccccgcca gcgcctcgcg ccccgaacca aactcggcaa ctacctgcaa atcaggttcc
     6601 agccccagca gctgcgcaaa gccggagcgg acgataaggt gatcgtctat aagggcaacg
     6661 gtgatcatgg tcttgtcctg gcgggtaata aaacgcgctt accttaacga taagcgcgat
     6721 gttgttcaag ccttgagcgg ttactgccaa aagctgcgct cttgttgctt gtggaaagaa
     6781 gtgatgcctt caaggacttg tatatcgact aaccattaaa aatgctg
//
LOCUS       DAFGPF010000193         6681 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFGPF010000193 DAFGPF010000000
VERSION     DAFGPF010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6681
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.193"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(23..970)
                     /gene="fmt"
                     /locus_tag="LSX49_004905"
     CDS             complement(23..970)
                     /gene="fmt"
                     /locus_tag="LSX49_004905"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBL7171174.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNIVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEDKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTTTKAAPGTILEANKQGIQVA
                     TGDGILNLLSMQPAGKKAMSVQDLLNSRREWFVPGNRLA"
     gene            complement(985..1494)
                     /gene="def"
                     /locus_tag="LSX49_004906"
     CDS             complement(985..1494)
                     /gene="def"
                     /locus_tag="LSX49_004906"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL7171175.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            1624..2748
                     /gene="dprA"
                     /locus_tag="LSX49_004907"
     CDS             1624..2748
                     /gene="dprA"
                     /locus_tag="LSX49_004907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL7171176.1"
                     /translation="MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLATTDYPGALFVEGEL
                     HALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            2720..3193
                     /locus_tag="LSX49_004908"
     CDS             2720..3193
                     /locus_tag="LSX49_004908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HBL7171177.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLSLET
                     REMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            3222..3764
                     /locus_tag="LSX49_004909"
     CDS             3222..3764
                     /locus_tag="LSX49_004909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBL7171178.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACGYV
                     RPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGMFIGCSNYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPISAE"
     gene            3769..4341
                     /gene="tsaC"
                     /locus_tag="LSX49_004910"
     CDS             3769..4341
                     /gene="tsaC"
                     /locus_tag="LSX49_004910"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HBL7171179.1"
                     /translation="MNNNLQGDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKRRPVDKGLILIAANYEQLKPYIDDTMLTDAQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            4346..5164
                     /gene="aroE"
                     /locus_tag="LSX49_004911"
     CDS             4346..5164
                     /gene="aroE"
                     /locus_tag="LSX49_004911"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBL7171180.1"
                     /translation="METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLTPINDFI
                     NTLNTFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTD
                     GIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIHALGMHELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKG
                     KTPFLAWCEQRGSKRTADGLGMLVAQAAHAFLLWHGVLPDVEPVIKLLQQELSA"
     gene            5161..5418
                     /locus_tag="LSX49_004912"
     CDS             5161..5418
                     /locus_tag="LSX49_004912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HBL7171181.1"
                     /translation="MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRF
                     TGDTPEQWLESFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(5394..5948)
                     /locus_tag="LSX49_004913"
     CDS             complement(5394..5948)
                     /locus_tag="LSX49_004913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBL7171182.1"
                     /translation="MSEVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPAGNPLTIGEDVTIGHKVMLHGCTIGN
                     RVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYMDQGNHTQP"
     gene            6419..>6681
                     /locus_tag="LSX49_004914"
     rRNA            6419..>6681
                     /locus_tag="LSX49_004914"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         1691 a         1565 c         1695 g         1730 t
ORIGIN      
        1 ccgggcttag aagagtggac tatcaggcca gacggttgcc cggtacaaac cattcccgac
       61 gagaattcag gaggtcttgc acgctcatcg ctttcttacc tgcaggttgc attgagagca
      121 gattcaggat gccatcacct gtcgctacct gaatgccttg tttattggct tcaaggattg
      181 ttcctggcgc agcctttgtt gtcgtatcga tgacagatgc tttccagact ttaaccggct
      241 gcccttcaat ttccagccag ctcattggcc atggattgaa agcgcgaatg caacgttcaa
      301 gctgtgctgc cgaaagtgac cagtcaatac gcgcttcttc tttactcaac ttttcggcgt
      361 aagtgacaag agtttcgtcc tgaacttctg gtttcgccgt gccgtctgcc agttgtttca
      421 acgtggtgat aagcccttgt gggccaagct ctgccagctt gtcgtacagc gtaccactgg
      481 tatcttctgc agtaatcggg caggagagct tatagagcat gtcaccggtg tctaaaccaa
      541 catccatttg cataatggtc acaccagttt ctgcatcacc cgcccatagt gagcgttgga
      601 ttggtgctgc accgcgccag cgtggcagca gtgaaccatg aacgttgata cagccaagac
      661 gcggcatctc cagcacagct ttaggcagaa ttaaaccata ggcgacgacg accataacat
      721 cagcctgcag atcggcgacc agttgctggt tttcttgtgg acgcagggaa acaggttgaa
      781 aaacgggcag acctttgtcc tcagccagaa ctttaaccgg gctgggcatc agttttttac
      841 cgcgtcctgc cggtcggtct ggctgggtga acacgccaac gatgttatga ccagaagaca
      901 acagcgcgtc gagatgacgc gctgcaaagt caggtgtacc cgcaaaaata atacgtagtg
      961 attctgacac gttaattctt atccttaagc ccgggctttc agacgatcca gtttttcaac
     1021 tttctgacga atacgttgtt gtttcagcgg tgacagataa tccataaaca gtttgccgac
     1081 caggtgatcc atctcatgct gaatacagat ggctaacaga ccgtctgctt ccagttcaaa
     1141 tggtttaccg tcgcggtcca gggcgcgaat tttaactttc tctgcgcgtg gcactaaagc
     1201 acgttgttca gggatcgaca ggcaaccttc ttcaatgcct gtttcgccgc ttttttctaa
     1261 aagctccgga ttgattaaca ccagccgttc gtcacggttt tccgaaacat caattacaat
     1321 gatacgttga tggatatcaa cctgggttgc cgccaggcca ataccttctt ctgcgtacat
     1381 cgtctcgaac atatcatcga cgatacgctg aatttctgca ttcacttctt ctaccggttt
     1441 agcaactttg cgaagccgct cgtccggaat atgtaacact tgcaaaactg acataaatct
     1501 ccagagatgt gttcaggagt tagaaagatt atttcttcta ttctagacaa atccccctct
     1561 gattgacagc atcactgacc aatcgcaaag attgctaagg ctgcttatgg cagggagata
     1621 aggatggtcg atacagaaat ttggctgcgt ttaatgagca tcagcagctt gtatggcgat
     1681 gatatggtcc gtatagctca ctggctggca aaacagtcgc atattgatgc ggttgtattg
     1741 cagcaaacag ggcttacatt gcggcaggca caacgctttc tttcatttcc gcgaaagagt
     1801 atcgaaagct cactttgttg gttggagcaa cccaaccatc atttaatccc tgcggacagc
     1861 gaattttatc ctcctcaact tctggcgacg acagattacc ccggcgcact gtttgttgaa
     1921 ggagaactgc acgcgttgca ttcatttcag cttgccgtag tggggagtcg ggcgcattca
     1981 tggtatggcg agcgatgggg acgattattt tgcgaaactc tggcgacgcg tggagtgaca
     2041 attacgagtg gactggcgcg tggaatcgat ggtgtggcgc ataaagcggc cttacaggta
     2101 aatggcgtta gcattgctgt attggggaat ggacttaata ccattcatcc ccgccgccat
     2161 gctccactgg ctgccagtct acttgagcaa ggtggtgctc tcgtctcgga atttcccctc
     2221 gatgttccac cccttgctta caatttccca cgaagaaatc gcattatcag tggtctaagt
     2281 aagggtgtac tggtggtgga agcggctttg cgcagtggtt cgctggtgac agcacgttgt
     2341 gcgcttgagc aggggcgtga agtttttgct ttgccaggtc caatagggaa tccgggaagc
     2401 gaagggcctc actggttaat aaaacaaggt gcgattcttg tgacggaacc ggaagaaatt
     2461 ctggaaaact tgcaatttgg attgcactgg ttgccagacg cccctgaaaa ttcattttat
     2521 tcaccagatc aggaagacgt ggcattgcca tttcctgagc tcctggctaa cgtaggagat
     2581 gaggtaacac ctgttgacgt cgtcgctgaa cgtgccggcc aacctgtgcc agaggtagtt
     2641 actcaactac tcgaactgga gttagcagga tggatcgcag ctgtacccgg cggctatgtc
     2701 cgattgagga gggcatgcca tgttcgacgt actaatgtat ttgtttgaaa cctatattca
     2761 cacagaagct gagttgcgtg tggatcaaga caaacttgaa caggatctta ccgacgcagg
     2821 atttgatcga gaagatatct acaatgccct gctttggctg gaaaagcttg cggattatca
     2881 ggaaggactg gcagaaccga tgcaactggc ctctgatcca ctctccatgc gtatttatac
     2941 ccctgaagag tgtgaaagac tggatgccag ctgtcgtggt tttttgcttt tccttgagca
     3001 aattcaggtg cttagccttg aaacccgtga aatggtgata gagcgagtgc tcgcgctgga
     3061 taccgcagag ttcgacctgg aagacctgaa atgggtaatc ctgatggtgt tgttcaatat
     3121 tccgggttgc gaaaatgcgt accagcaaat ggaagaatta ctctttgaag tgaatgaagg
     3181 tatgctgcat taatcatttc tttaattcag cataagttgt tatggcgaaa tcagcactgt
     3241 tcacggtgcg taataatgag tcctgcccaa agtgcggggc tgaactagtt attcgatccg
     3301 ggaaacacgg tccgtttctt ggatgctcac agtatccggc atgtggctac gtccgtcctc
     3361 tgaaatcttc agcggatgga catattgtca aagttctgga ggggcaggtt tgccctgcat
     3421 gtggcgcaaa tctggtatta cgccagggac gctttggtat gtttattggt tgcagtaact
     3481 accctgaatg cgaacatacc gaacttatcg ataaaccgga cgaaacagca attacatgcc
     3541 cccaatgccg gacgggccat ctggttcagc gccgctcccg ttatggcaaa acatttcact
     3601 cctgtgatcg ctacccggag tgtcaatttg ccattaactt caaacccata gctggagaat
     3661 gccctgagtg ccattatccg ctactcatcg aaaagaaaac cgcgcagggt gtaaaacact
     3721 tttgtgccag taaacaatgt ggaaagccga tttcggcgga ataataacgt gaataataac
     3781 ctgcaaggag acgctatcgc agctgcgata gatgtcctca atgaagaacg tgtcatcgcc
     3841 tatccaacgg aagccgtttt cggtgtcggg tgcgatcctg atagcgaaac agcagtgatg
     3901 agactgttgg agttaaaacg gcgtccggtt gataaggggc tgattttaat cgcggcaaat
     3961 tacgagcagc ttaaacccta tattgatgac accatgctga ctgacgcgca gcgtgaaacc
     4021 attttttccc gctggccagg tcctgtaacc tttgtctttc ccgcgcctgc gacaacaccg
     4081 cgctggttga cgggccgctt tgattcgctt gctgtacgag tcaccgacca tccgttggtg
     4141 gttgctttgt gccaggctta tggtaaaccg ctggtttcta ccagtgccaa cttgagtgga
     4201 ttgccacctt gtcgaacagt agacgaagtt cgcgcacaat ttggcgctgc gttcccggtt
     4261 gtgcctggtg aaacgggggg gcgtttaaat ccttcagaaa tccgcgatgc cctgacgggt
     4321 gaactgtttc gacaggggta acataatgga aacctatgct gtttttggta atccgatagc
     4381 ccacagcaaa tcgccattca ttcatcagca atttgctcag caactgaata ttgaacatcc
     4441 ctatgggcgt gtgttgacac ccatcaatga tttcatcaac acactgaaca ctttctttag
     4501 tgctggtggt aaaggtgcga atgtgacggt gccttttaaa gaagaggctt ttgccagagc
     4561 ggatgagctt actgaacggg cagcgttggc tggtgctgtt aataccctca agcggttaga
     4621 agatggacgc ttgctgggtg acaataccga tggtataggt ttgttaagcg atctggaacg
     4681 tctgtctttt atccgtcctg gtttacgtat tttgctcatc ggcgctggtg gagcatctcg
     4741 cggcgtacta ctgccactcc tttccctgga ctgtgcggtg acaatcacta atcggacggt
     4801 atcccgcgcg gaagagttgg ctaaattgtt tgcgcacact ggcagtattc acgcgttggg
     4861 tatgcacgaa ctggaaggtc atgagtttga tctcattatt aatgcaacat ccagtggcat
     4921 cagtggtgat attccggcga tcccgtcatc gctcattcat ccaggcattt attgctatga
     4981 catgttctat cagaaaggaa aaactccttt tctggcatgg tgtgagcagc gaggctcaaa
     5041 gcgtactgct gatggtttag gaatgctggt ggcacaagcg gctcatgcct tccttctttg
     5101 gcatggcgtt ctgcctgatg tagaaccggt catcaaacta ttgcaacagg agttgtcagc
     5161 gtgaatcagg ccatccagtt tccggatagg gaagagtggg acgagaataa aaaatgtgta
     5221 tgttttcccg ctctcgtgaa tggtatgcaa ctgacatgtg cgatctctgg cgagagtctg
     5281 gcgtatcgct ttactggaga tacaccagaa cagtggttag agagttttcg tcagcatcgc
     5341 tgggacctgg aagaagaagc ggaaaactta attcaggaac aaagtgaaga tgatcaaggt
     5401 tgggtgtggt taccctgatc catatattcg tccttccatt tcacgtagtt atttgcggaa
     5461 tagcgtaacc cagccttctc ttcatcactt aacgggcgga tctgtttgac ggggctaccg
     5521 agatacagat atccgctctc cagccgttta ttttgtggga ccaggctacc tgcaccaatc
     5581 atcacatcat cttctactat tgcgccatca agtaaaattg agcccatccc aaccaaaact
     5641 cgattgccaa tggtgcagcc gtggagcatc accttgtgac caatagtgac atcttcgcca
     5701 atggttaatg ggttgccagc tgggttgtac gaggatttat gagtgacgtg caacatactg
     5761 ccatcctgga tattggtgcg tgctccgatc tgtacataat gtacatctcc acgaatcaca
     5821 acgagcggcc agatccccac atcatcagcc agacgaacgt caccaatcac gacgctgcta
     5881 tcgtcgatca ttacgcgctg accgatttgt ggaaaaagat cgcggtatgg gcgtaaaacc
     5941 tcagacatac tcacctcaac aataaatgat ttactaatga ctttgggtac attattggcc
     6001 ttgtgcaagt cttttagtat gcaaaaaagc accgttttgt gtgcgaatgc agcaaaaagg
     6061 gtgaaaaaac aacaaacaga aaaaaagatc aaaaaagtac ttgtgcaaaa aattgggatc
     6121 cctataatgc gcctccgttg agacgacaac gtgaaacact tcacaagata gtcgtaacaa
     6181 caaagagaaa aatcctgaaa ttcagggttg actctgaaag aggaaagcgt aatatacgcc
     6241 acctcgcgac agtgagctga aaaccgcgtc gcaactgctc tttaacaatt tatcagacaa
     6301 tctgtgtggg cactcgaaga tacggattct tgacgtcgca agacgaaaaa tgaataccaa
     6361 gtctcaagag tgaacacgta attcattacg aagtttaatt cacgagcatc aaacttttaa
     6421 attgaagagt ttgatcatgg ctcagattga acgctggcgg caggcctaac acatgcaagt
     6481 cgaacggtaa caggaagcag cttgctgctt tgctgacgag tggcggacgg gtgagtaatg
     6541 tctgggaaac tgcccgatgg agggggataa ctactggaaa cggtagctaa taccgcataa
     6601 cgtcgcaaga ccaaagaggg ggaccttagg gcctcttgcc atcggatgtg cccagatggg
     6661 attagctagt aggtggggta a
//
LOCUS       DAFGPF010000194         6499 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFGPF010000194 DAFGPF010000000
VERSION     DAFGPF010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6499
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.194"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            53..940
                     /locus_tag="LSX49_004915"
     CDS             53..940
                     /locus_tag="LSX49_004915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL7171183.1"
                     /translation="MLRENNFNLIIKNNVEHLLKSESTALRESICAVIAGKDCYQADT
                     LSLLSGVKIISRFGTGIDNIDLRAAQQSGIVVNNAVGINSNAVAEFIIGLIFASMRNI
                     PGSYHAMQNGYWGESHGCELQGKRIGLVGYGNIGKILAKRLSGFDVELLAFDKQPDYQ
                     VADKAGVQFVSIEDIFMQSHAIIVLLPFSSELENFISHKYLSMMRNGALIINAARGKL
                     LDEGALLQVIEERNVFAALDVFSSEPLAQFSPLLHAKNIITTPHIAAATVESYQQTGI
                     HVAQSIIDYFAGRKIKNVL"
     gene            complement(1240..2616)
                     /locus_tag="LSX49_004916"
     CDS             complement(1240..2616)
                     /locus_tag="LSX49_004916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ImpA family N-terminal
                     domain-containing protein"
                     /protein_id="HBL7171184.1"
                     /translation="MASNANFISQFVMGGDPCTYKESGELQAEMSKLTHPARPDVDWR
                     QVEKLCLALFRQNGVELQTLVCYVLAITRRQGLAGMADGLGSLDILLQRWADFWPVQV
                     HSRISLLSWVTEKMQQALRTLDIQYQDLPQIYRCVQHLSAIETTLQQCELWHMTKLDV
                     LAGQFRNTALRLERLAPQGAETTITPPELPRREMNQPKKSEESPQPVFATRPAQQNDK
                     DASPPVSSPEISRQRTWPIFMAGMVVMAGLGGTGLWGWSQLNQPDALIQRIQLSVMPL
                     PQSLESGELAKLDVKDKALLAQDRTIAASQMQLEQLNKLPARWPLEQGYRQLRQLDAL
                     WPDNPQVRALNVQWRKQRELSALSAEALNGYAQAQSQLQRLSAQLDALDERKGRYLTG
                     SELKTAVYGIRQSLKEPPLEELLRQLEEQKQTGEISPTLLTQIDTRLNQLLNRYVILL
                     DTKVEQSQ"
     gene            complement(2616..3044)
                     /gene="tssE"
                     /locus_tag="LSX49_004917"
     CDS             complement(2616..3044)
                     /gene="tssE"
                     /locus_tag="LSX49_004917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HBL7171185.1"
                     /translation="MSTPSLYEMLTFSFSGELPLEQVRERDQLILSVMDNMQRIINCR
                     AGTLAHLPDYGLPDLSLIHQGMAAGIHGLMRQIEETLLRYEPRLSQIQVELLPQPRPG
                     HLNYLIHAQLPDTGWIRFDGVFSPEGRIVLRHLKQQERAY"
     gene            complement(3048..3584)
                     /gene="tssJ"
                     /locus_tag="LSX49_004918"
     CDS             complement(3048..3584)
                     /gene="tssJ"
                     /locus_tag="LSX49_004918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HBL7171186.1"
                     /translation="MFPIRFKRPALLCMAMLTVVLSGCGLIQKVVDESKSVASAVFYK
                     QIKILHLDFFSRSALNTDAEDTPLSTMVHVWQLKTREDFDKADYDTLFMQEEKTLEKN
                     VLAKHTVWVKPEGTASLNVPLDKETQFVAIIGQFYHPDEKSDSWRLVIKRDELEADKP
                     RSIELMRSDLRLLPLKDK"
     gene            complement(3565..4644)
                     /gene="tssG"
                     /locus_tag="LSX49_004919"
     CDS             complement(3565..4644)
                     /gene="tssG"
                     /locus_tag="LSX49_004919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HBL7171187.1"
                     /translation="MDRASQPARTGLTDRLAPDIARINFYRFCQLLEQRQQNAPLGST
                     DSPAADAVRFRPHPGMGFPVSELKNVERDVDNPDAPPTVRTTFLGLYGVDSPLPTAYL
                     DYITQRHDGHDAVMAFLDIFNHRFITQYYRIWRKYNYPASFEAGAVDDISRCLLGLIG
                     LGIPGSENHIATPVSRFLALLSVMRLPTRTAEGVTALVGLLAPLTKATVVPHDPQPVI
                     LPAPAGLSKNSPISLKTRTLLGRTGTDVNSQLLLKLYTEDAAEARGWLPGGQLHSDLL
                     VLLRVYLGWRCQARLQLTLPVSLLPAARLGKQRVQISRTGILRASFAAPATGTVTVSL
                     GRYQGLIPAFSIRNRESMTHVSYSF"
     gene            complement(4608..6368)
                     /gene="tssF"
                     /locus_tag="LSX49_004920"
     CDS             complement(4608..6368)
                     /gene="tssF"
                     /locus_tag="LSX49_004920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HBL7171188.1"
                     /translation="MDDLTQRYFEAEMRYLREAGKEFAQAYPDRAAMLNLDKPGARDP
                     YVERLFEGFAFLMGRLREKLDDDLPELTEGLVSLLWPHYLRTIPSLSVVELTTDHQQM
                     KQSDTLKEFQVLSRPIGERRTRCVYSATRDITLHPLALPDVSLQYEPDGRSVIRLRFE
                     CGPLVGDWSQIDLSRLPLYLSADSPVACALHRALTLGTQQFWLRLPGQGRRVLDAHFS
                     PMGFDDDDRLWPKGESAFSGYQLLLEYFTFREKFMFVALNGLEQVAWPEGITGFEIDV
                     LLNENWPHDLPFDSDNIRLHCVPVINLFPLEADPLHLSPLENEFLLRPMRIQDGHTEI
                     YSVDNIISSRHTGSQAYVPFSSFRHRGGMLRHDAPERYYHTRVKRGPSGLHDTWLILG
                     GDAFDTDRMLEDETLSLSLTGTNGQLPRKALQSTLLDTPVHASQNVLRVRNLCAPTQP
                     CYPPARDRFHWRVLSHLGSNFLSMMDNAEILRGTLALYDWTESEMNRRRLAAIVDVQH
                     SLIQRFERGFLLRGVDIQVTLDSNGFAGEGDITLFGELLHRFFALYADIHLFTQLTLI
                     LQPTGKCLQWTEHHSQRVPG"
BASE COUNT         1498 a         1736 c         1730 g         1535 t
ORIGIN      
        1 tgttctggtc accgtcccca gcttttcagc acgctgtgtt tccgccagca agttgctaag
       61 agagaataat tttaatctta ttattaagaa taatgtggag catctgctta aatcagaatc
      121 cactgcatta cgagaatcta tttgcgcggt catcgccgga aaagattgtt atcaggcgga
      181 cacgctatca ttgctgtctg gtgtgaaaat aatatcgaga ttcgggacgg ggatagacaa
      241 tattgatctt cgtgcggcac agcaatccgg tattgttgtc aataatgcgg ttgggattaa
      301 ttcaaatgcg gttgcggaat ttatcattgg acttatcttc gcgagcatga gaaatatccc
      361 tggcagctat catgcgatgc aaaatggcta ctggggtgag tcgcatggct gtgaattaca
      421 agggaaacgg attggcctgg ttggctacgg taatataggt aaaattctgg cgaaaaggtt
      481 atccggtttt gatgttgagc ttttagcttt tgacaaacaa cccgactatc aggttgctga
      541 caaagctgga gttcagtttg tatcaattga agatatcttt atgcagtcgc atgccatcat
      601 tgttcttttg cctttttctt ctgagctgga gaacttcatt agtcataaat atttgtcgat
      661 gatgcgcaat ggtgctctga tcatcaatgc cgcaagggga aagttgctgg atgagggcgc
      721 tttacttcag gtgattgaag aacgaaatgt gtttgcggcg ctggatgtgt ttagctctga
      781 accgttggcg caatttagcc cactgctaca tgccaaaaat atcattacaa cgccgcatat
      841 tgcggccgcc accgttgagt cataccagca aaccgggata cacgttgccc agtcgataat
      901 tgattacttc gcaggaagga agataaaaaa cgtgttgtga gttcagcgaa caaagatttt
      961 aaatacaaaa aaaccgcaat ttgtagaaca cattgcggtt tgtcagcatt ctaataaatt
     1021 ggttgcgggg gccacagtca agaggttaat ccaatctttt gaaacttaag gtattcactg
     1081 ttcccgaacc caagctatct accgaaatat acactcatta tctgatgtga atcaacgagt
     1141 agatcgaatg gcctgttcct ctcttttttg tacacaaaga ctccttttaa aaaatagcaa
     1201 ggtcacatat cccttattgg tacataaatc ccccgatgtt tactgacttt gttccacctt
     1261 cgtatccagt aaaatgacat agcgattcag caactgattt aaccgggtat caatctgcgt
     1321 caacagcgtc ggcgaaatct ctccggtctg tttttgctct tccagttgcc gaagcagttc
     1381 ttccagcggc ggctccttta acgactgccg gatgccgtac accgccgttt ttagttccga
     1441 accggtcaga tatctcccct tacgttcatc cagtgcatcc agttgtgccg acaggcgctg
     1501 tagctgactc tgcgcctgtg cgtagccatt cagtgcctct gcggacaggg cgctcagttc
     1561 ccgctgttta cgccactgca cgttcagcgc cctgacctga ggattatccg gccacagggc
     1621 atcaagctgg cgtagctggc gatatccctg ctccagcggc cagcgggcag gtaatttgtt
     1681 taactgctcc agttgcatct gacttgccgc aattgttctg tcctgagcca gcagcgcctt
     1741 atcctttaca tccagctttg ccagttcgcc gctctccagc gactgcggca acggcatgac
     1801 agacagttgt attcgctgga ttagcgcgtc cggctgatta agctgcgacc agccccataa
     1861 tcctgttccg ccgagaccgg ccatcacaac cattccggcc ataaatatcg gccatgtccg
     1921 ctgtcgggag atttcagggg atgacacggg tggactggca tccttatcgt tttgctgagc
     1981 gggtctcgtt gcaaaaaccg gctgtggact ttcttctgac tttttcggtt gattcatttc
     2041 ccggcggggt aattcagggg gagtgatagt ggtttccgct ccctgaggcg ccagccgttc
     2101 cagacgcaat gcggtattgc gaaactgccc ggccagcaca tccagtttcg tcatatgcca
     2161 cagttcacac tgttgcagcg tggtttcgat ggcggaaaga tgctgtacac aacggtagat
     2221 ctgcggcaga tcctgatact gaatatccag cgttctcagt gcctgctgca ttttttctgt
     2281 gacccagctg agcagtgata ttctggaatg tacctgtacc ggccagaagt cagcccagcg
     2341 ctggagcagt atatccagtg agccgagtcc gtctgccatc cctgccagcc cctgccgtct
     2401 ggttatcgcc agtacgtaac agaccagcgt ctgtagttcc acgccatttt gccggaacag
     2461 cgcgaggcag agtttttcca cctgacgcca gtccacatcc ggtcgggccg ggtgagtcag
     2521 tttactcatt tcagcctgca gttcaccgga ttccttataa gtacagggat cgccgcccat
     2581 gacgaactgg ctgataaaat tcgcgttact tgccatcagt acgcccgctc ctgttgtttg
     2641 agatgacgca gaacaattcg tccttccgga gaaaatacgc catcaaagcg tatccagccg
     2701 gtatcgggaa gctgcgcgtg gatcaggtaa ttaagatgcc ccggacgggg ctgggggagt
     2761 aactccacct gtatctgact caggcgtggt tcataacgca gcagcgtttc ttcaatctga
     2821 cgcatcaggc catgaatacc cgcagccatc ccctgatgga tcagactgag atccggcaga
     2881 ccgtaatccg gcaaatgcgc cagcgtgcct gcccggcagt tgataatgcg ttgcatattg
     2941 tccatcacgg aaaggataag ctgatcccgc tctctgacct gttccagcgg taactcgccg
     3001 ctgaaactga acgtcagcat ttcatataag gaaggtgtcg acatcggtta tttatccttg
     3061 agaggcagca gtcgcaggtc gcttctcatc agttcaatcg agcgcggctt gtcggcctcc
     3121 agttcgtccc ttttgatcac cagacgccag ctgtcgcttt tttcatcagg gtgataaaac
     3181 tgcccaataa tggcgacaaa ctgcgtctct ttatccagcg gcacattcag ggatgccgtg
     3241 ccttccggtt ttacccagac ggtgtgtttt gccagtacgt tcttctccag cgtcttctct
     3301 tcctgcataa acagggtgtc ataatccgcc ttgtcaaaat cttcgcgggt tttcagttgc
     3361 cagacatgca ccatcgtgga aagcggcgta tcttccgcat ccgtattcag ggcacttcgg
     3421 gagaagaaat cgagatgcag tattttgatt tgcttgtaga aaacggctga ggccacgctt
     3481 ttcgattcat ccaccacttt ctgaatcagc ccgcagccgc tcagaacaac cgtcagcatc
     3541 gccatacaga gcagcgccgg acgtttaaaa cgaataggaa acatgagtca tactctccct
     3601 gttacgaatg gaaaaagcgg gtattaatcc ctgataacgc cccagactga ccgtcactgt
     3661 tccggtcgcg ggcgcggcaa aggaggcgcg aaggatgccg gtacggctaa tctgtacacg
     3721 ctgttttccc agccgggcag caggcaacag gctgacgggc agcgtcagtt gcagtcgggc
     3781 ctgacagcgc cagcccagat aaacgcgcag cagcaccagc aaatcgctgt gcagttgccc
     3841 gccgggcagc cagccacgtg cttctgcggc atcttcggta tacagtttca gcagcaactg
     3901 gctgttgacg tcggtgccgg tacgccccag cagcgttcgc gttttcaggc tgatgggtga
     3961 attttttgac agacccgcag gggccgggag aattacaggc tgcggatcat gaggcaccac
     4021 cgtcgctttc gtcagcgggg caagcagtcc caccagtgcc gtaacgcctt ccgccgtgcg
     4081 cgtcggcagg cgcatcacgc tgagcagggc cagaaaacgg gataccggcg tggcgatatg
     4141 gttctcgctg ccgggaatac ccagcccgat gagtcccagc aggcaacggg aaatgtcatc
     4201 cactgcacct gcttcaaacg acgccgggta gttatatttg cgccagatgc ggtaatactg
     4261 ggtgataaag cgatggttaa aaatatcgag aaacgccatc accgcgtcat gtccgtcatg
     4321 acgctgggta atgtagtcca gataggcggt tggcagtggc gaatccacgc cgtacaggcc
     4381 gagaaaagtg gtgcgcactg tgggtggcgc gtcgggattg tccacgtcac gttcaacgtt
     4441 ctttaactcg ctgaccggaa agcccatccc cggatgagga cgaaagcgca ccgcatcggc
     4501 ggcggggctg tcggtactgc ccagcggcgc gttctgctgg cgctgttcca gcaactggca
     4561 aaaacggtaa aaattgatcc gcgcaatatc cggggccagc cggtcggtca gcccggtacg
     4621 cgctggctgt gatgctctgt ccattgcagg cactttcctg tgggttgcag aattaaggtt
     4681 agttgagtga ataagtggat atcggcatac agtgcgaaga agcggtgcag cagttcacca
     4741 aacagcgtga tatcaccttc tccggcaaag ccgttactgt ccagcgtcac ctgaatatcc
     4801 acgccacgca gcagaaagcc tctttcaaaa cgctgtatca ggctgtgctg aacgtcgaca
     4861 atcgccgcca gacgacggcg gttcatctcg ctttcggtcc agtcgtacag cgccagcgtg
     4921 ccgcgcagaa tttcggcgtt atccatcatc gataaaaagt tagaaccaag gtggctgagc
     4981 acccgccagt ggaagcggtc acgcgccggg ggatagcagg gctgcgtcgg ggcgcacagg
     5041 ttgcgcaccc gcaggacgtt ctgtgaggca tgaactggcg tatcgagcag cgtgctctgt
     5101 aaagctttac ggggaagctg cccgttagta ccggtcaggc ttaaggacag ggtttcatcc
     5161 tccagcatcc ggtcagtatc aaacgcatcg ccgcccagaa tcagccaggt gtcatgcagg
     5221 ccggaagggc cgcgctttac ccgcgtgtgg taatagcgtt ccggcgcatc gtggcgcagc
     5281 atcccgcccc ggtgacgaaa gctggagaat ggcacatacg cctgactgcc ggtatggcgc
     5341 gaagaaataa tgttgtcgac ggaataaatc tcggtatgcc cgtcctgaat gcgcatcggg
     5401 cgcagcagaa attcgttttc cagtggcgaa aggtgtaacg gatcggcttc cagcggaaac
     5461 aggttgatga ccggcacgca gtgcagacgg atattatcgc tgtcaaacgg caggtcgtga
     5521 ggccagttct cgttcagcaa cacgtcaatc tcaaagccgg ttatcccctc cggccatgca
     5581 acctgctcca gcccgttcag cgccacgaac ataaacttct cgcggaaggt gaaatactcc
     5641 agcagcaact ggtagccgct gaacgccgat tcgcctttcg gccacagtcg gtcatcgtca
     5701 tcaaaaccca tcggggaaaa gtgcgcgtcc agcacacggc gtccctgccc tggcagacgc
     5761 agccagaact gctgcgtacc aagcgttaaa gcccggtgca gcgcacaggc caccgggctg
     5821 tcggcactga ggtacagcgg caggcgggat aaatcaatct gtgaccagtc accaaccagc
     5881 gggccgcatt caaagcgcag acggataacc gagcgtccgt ccggttcata ttgcaatgac
     5941 acgtccggca acgccagcgg atgcagcgtg atatcccgcg tggcgctgta gacgcagcgg
     6001 gttctgcgtt cgccgatggg acgggatagc acctgaaact ctttcagcgt atcactttgc
     6061 ttcatttgtt ggtgatccgt ggtcagttcg accacggaaa gcgacggaat agtgcgcagg
     6121 tagtgcggcc acagcaggct gaccagccct tcagtcagtt ccggcagatc gtcgtccagc
     6181 ttttcgcgca ggcggcccat taaaaaagcg aagccctcga acaggcgctc cacataggga
     6241 tcgcgtgcgc cgggtttatc aagattaagc atcgcagcgc ggtcggggta agcctgcgca
     6301 aattctttcc ccgcttcacg caggtagcgc atttcggcct caaagtagcg ttgggtcagg
     6361 tcgtccatcg gaggatttat ctttcctttt attgaaatta ataccaacga gtagtgagat
     6421 tagaattttt tattttcaga atcctaagga catatagatg gatcatttat ttcaaaagaa
     6481 aaatcggact ccatactag
//
LOCUS       DAFGPF010000195         6363 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFGPF010000195 DAFGPF010000000
VERSION     DAFGPF010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6363
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.195"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            16..906
                     /gene="alsR"
                     /locus_tag="LSX49_004921"
                     /gene_synonym="rpiR"
     CDS             16..906
                     /gene="alsR"
                     /locus_tag="LSX49_004921"
                     /gene_synonym="rpiR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418513.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="als operon DNA-binding transcriptional repressor
                     AlsR"
                     /protein_id="HBL7171189.1"
                     /translation="MSQSEFDSALPNGIGLAPYLRMKQEGMTENESRIVEWLLKPGNL
                     SCAPAIKDVAEALAVSEAMIVKVSKLLGFSGFRNLRSALEDYFSQSEQVLPSELAFDE
                     APQDVVNKVFNITLRTIMEGQSIVNVDEIHRAARFFYQARQRDLYGAGGSNAICADVQ
                     HKFLRIGVRCQAYPDAHIMMMSASLLQEGDVVLVVTHSGRTSDVKAAVELAKKNGAKI
                     ICITHSYHSPIAKLADYIICSPAPETPLLGRNASARILQLTLLDAFFVSVAQLNIEQA
                     NINMQKTGAIVDFFSPGALK"
     gene            965..1900
                     /gene="alsB"
                     /locus_tag="LSX49_004922"
     CDS             965..1900
                     /gene="alsB"
                     /locus_tag="LSX49_004922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose transporter substrate-binding protein"
                     /protein_id="HBL7171190.1"
                     /translation="MNKYLKYFSGTLVGLMLSTSAFAAAEYAVVLKTLSNPFWVDMKK
                     GIEDEAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVAR
                     AWKKGIYLVNLDEKIDMDNLKKAGGNVEGFVTTDNVAVGAKGASFIIDKLGAEGGEVA
                     IIEGKAGNASGEARRNGATETFKKASQIKLVASQPADWDRIKALDVATNVLQRNPNIK
                     AIYCANDTMAMGVAQAVANAGKTGKVLVVGTDGIPEARKMVEAGQMTATVAQNPADIG
                     ATGLKLMVDAEKSGKVIPLDKAPEFKLVDSILVTQ"
     gene            2028..3560
                     /gene="alsA"
                     /locus_tag="LSX49_004923"
     CDS             2028..3560
                     /gene="alsA"
                     /locus_tag="LSX49_004923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter ATP-binding protein
                     AlsA"
                     /protein_id="HBL7171191.1"
                     /translation="MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGK
                     STLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLY
                     IGRHLTKKICGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL
                     MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVM
                     KDGSSVCSGMVSDVSNDDIVRLMVGRELQNRFNAMKENVSNLAHDTVFEVRNVTSRDR
                     KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLD
                     AVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQ
                     RELLALKCHSVNQNITELSGGNQQKVLISKWLCCRPEVIIFDEPTRGIDVGAKAEIYK
                     VMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALP
                     QE"
     gene            3539..4519
                     /gene="alsC"
                     /locus_tag="LSX49_004924"
     CDS             3539..4519
                     /gene="alsC"
                     /locus_tag="LSX49_004924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter permease"
                     /protein_id="HBL7171192.1"
                     /translation="MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSS
                     EYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGI
                     DPFLAALIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYG
                     FSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGI
                     DVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGK
                     GRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK"
     gene            4530..5225
                     /gene="alsE"
                     /locus_tag="LSX49_004925"
     CDS             4530..5225
                     /gene="alsE"
                     /locus_tag="LSX49_004925"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allulose-6-phosphate 3-epimerase"
                     /protein_id="HBL7171193.1"
                     /translation="MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTL
                     SPFFVSQVKKLASKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEI
                     RRHGMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKVAELKAW
                     RERKDLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQIL
                     AAKSEVQPHAKTA"
     gene            5209..6138
                     /gene="alsK"
                     /locus_tag="LSX49_004926"
     CDS             5209..6138
                     /gene="alsK"
                     /locus_tag="LSX49_004926"
                     /EC_number="2.7.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allose kinase"
                     /protein_id="HBL7171194.1"
                     /translation="MQKQHNVVAGVDMGATHIRFCLRTAEGETLHCEKKRTAEVIAPD
                     LVSGIGEMIDEQLRRFNARCHGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKL
                     ENTLNCPVEFSRDVNLQLSWDVVENRLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGV
                     AGELGHIPLGDMTQHCACGNSGCLETNCSGMALRRWYEQQPRNYPLSDLFVHAENAPF
                     VQSLLENAARAIATSINLFDPDAVILGGGVMDMPAFPRETLIAMTQKYLRRPLPYQVV
                     RFIAASSSDFNGAQGAAILAHQRFLPQSCAKVP"
BASE COUNT         1658 a         1506 c         1623 g         1576 t
ORIGIN      
        1 ggacaagaga acgtgatgag ccagtcagag tttgattcag cgcttccgaa cggtatcggg
       61 ttagcgcctt acctgcgaat gaagcaggaa ggaatgacag aaaacgaaag ccgcatcgtg
      121 gagtggttac tcaaacccgg taacctgagt tgtgcacccg caattaaaga tgtcgcagaa
      181 gctctggcgg tatctgaagc gatgatcgtt aaggtatcaa agctgctggg gtttagcggc
      241 tttcgtaact tacgcagtgc gctggaagat tatttttctc agtcagaaca agtattgccg
      301 tccgagttgg cttttgatga agcgccgcag gatgtggtga ataaggtatt taacatcact
      361 ttacgcacca ttatggaagg tcagtcgatc gtcaacgttg atgagatcca ccgtgccgcc
      421 cgctttttct atcaggccag acagcgggat ttgtacggtg ccggaggatc aaatgcaatc
      481 tgtgctgatg tacagcacaa gtttttacgc attggcgtac gctgccaggc ctatccggac
      541 gctcacatca tgatgatgtc tgcttcgttg ttacaggaag gagatgtggt gctggtggtg
      601 acccattccg ggcgaaccag tgatgtaaaa gcagctgtag aactggcaaa aaagaacggg
      661 gcaaagatta tttgtataac gcatagctac cattcaccga tagcgaagct ggccgattat
      721 attatttgct caccggcccc ggaaacaccg ttattaggtc gtaatgcctc ggcaagaata
      781 ttacaactaa ctttgctgga cgcgtttttt gtctctgtcg cccagctcaa cattgaacaa
      841 gctaatatta atatgcaaaa aaccggcgca attgttgatt tcttctcacc aggcgcgctg
      901 aaataagaaa aaggtaattc cgccatcgcg gagttaccta tccccttacc gtgagaacat
      961 gattatgaat aaatatctga aatatttcag cggcacactc gtgggcttaa tgttgtcaac
     1021 cagcgctttt gctgccgccg aatatgccgt cgtattgaaa acactctcca acccattttg
     1081 ggtagatatg aaaaaaggca ttgaagatga agcaaaaacg ctgggcgtca gcgttgatat
     1141 ttttgcctct ccttcagaag gcgattttca atctcaattg cagttatttg aagatctcag
     1201 taataaaaat tacaaaggta tcgccttcgc accattatcc tcagtgaacc tggtcatgcc
     1261 tgtcgcccgc gcatggaaaa aaggcattta tctggtcaat ctcgatgaaa aaatcgacat
     1321 ggataatctg aaaaaagcag gcggtaatgt ggaaggtttt gtcaccaccg ataacgttgc
     1381 cgtcggggcg aaaggcgcgt cattcattat tgacaagctg ggtgccgaag ggggtgaagt
     1441 tgcaattatt gaaggtaaag ccggtaacgc ctccggtgaa gcgcgtcgta atggtgccac
     1501 cgaaaccttc aaaaaagcaa gccagatcaa gcttgtcgcc agccagcctg ccgactggga
     1561 ccgcattaaa gcactggatg tcgccactaa cgtgttgcaa cgtaatccga atattaaagc
     1621 gatctattgc gcgaatgaca cgatggcaat gggtgttgct caggctgtcg caaacgccgg
     1681 aaaaacggga aaagtgctgg tcgtcggtac agatggcatt ccggaagccc gcaaaatggt
     1741 ggaagccgga caaatgaccg cgacggttgc ccagaacccg gcggatatcg gcgctacggg
     1801 tctaaagctg atggttgacg ctgaaaaatc cggcaaggtt atcccgctgg ataaagcacc
     1861 ggaatttaaa ctggtcgatt caatcctggt cactcaataa aactaaatga tgccggatag
     1921 tgatgctaat gaagtgtctt atccggccaa caaaataacc tgaacgtaga cctgataagt
     1981 gtagcccatc aggcaataat acgatatttc gtgcagagag gttatttatg gccacgccat
     2041 atatatcgat ggcggggatc ggcaagtcct ttggtccggt tcacgcatta aagtcggtta
     2101 atttaacggt ttatcctggt gaaatacatg cattactagg agaaaatggc gcgggtaaat
     2161 ccacgctaat gaaagtgtta tccggaatac atgagccaac caaaggcacc attaccatta
     2221 ataacattaa ctataacaaa ctggatcata aattagcggc acaactcggt atcgggatta
     2281 tttatcagga actcagcgtt attgatgaat taaccgtact ggaaaattta tatattggtc
     2341 gtcatctgac gaaaaaaatc tgcggtgtca atattatcga ctggcgagaa atgcgtgtcc
     2401 gcgccgcaat gatgttatta cgcgtgggct tgaaagttga tttagatgag aaagtggcga
     2461 acttatctat cagccacaag cagatgctgg aaattgccaa aacgctgatg ctcgacgcca
     2521 aagtcatcat catggatgaa cccacctcct cactcaccaa taaagaggtg gactatctgt
     2581 ttctgatcat gaatcagttg cgtaaggagg gtacggctat cgtctatatc tcgcataaat
     2641 tggcggaaat tcgccgtatt tgcgaccgct atacggtgat gaaagacggc agcagcgttt
     2701 gcagcggcat ggtgagcgat gtgtcaaatg acgatatcgt ccgtctgatg gtaggccgcg
     2761 aactgcaaaa ccgttttaac gcgatgaagg agaatgtcag caaccttgcg cacgatacgg
     2821 tttttgaggt gcgcaacgtc accagccgtg acagaaaaaa ggtccgggat atctcattta
     2881 gcgtctgccg gggagaaata ttaggctttg ccggactggt cggttccgga cgtactgaac
     2941 tgatgaactg cctgtttggc gttgataaac gcgctggcgg agaaatccgt cttaatggca
     3001 aagatatctc tccacgttct cccctggatg ccgtgaaaaa agggatggct tacatcactg
     3061 aaagccgccg ggataacggc tttttcccca acttttctat cgctcagaac atggctatca
     3121 gccgcagtct gaaagacggc ggctataaag gcgcgatggg gttgtttcat gaagttgacg
     3181 agcaacgtac cgctgaaaat caacgcgaac tgctggcgct gaaatgtcat tcggtaaacc
     3241 agaacatcac tgaactctcc ggcggtaacc agcagaaagt cctgatctcc aaatggctgt
     3301 gctgtcgccc ggaagtgatc attttcgatg aacctacccg tggcatcgac gttggcgcga
     3361 aagccgaaat ttacaaagtg atgcgccaac tggcggacga cggaaaagtc atcctgatgg
     3421 tgtcatctga actacctgaa attatcaccg tctgcgaccg catcgccgtg ttctgcgaag
     3481 gacgactgac gcaaatcctg acgaatcgcg atgacatgag cgaagaggag attatggcat
     3541 gggctttacc acaagagtaa aaagcgaagc gagcgagaag aaaccgttca actttgcgct
     3601 gttctgggat aaatacggta ctttttttat cctggcgatc atcgtcgcca tttttggttc
     3661 gctgtcgtca gaatattttc tgaccaccaa taatattacc cagatttttg tgcaaagctc
     3721 cgtgacggta ctgatcggca tgggggaatt cttcgctatc ctggtcgccg gtatcgacct
     3781 ttcggttggc gcgattctgg cgctttccgg tatggtgacc gctaaactga tgttggcagg
     3841 tattgatccg tttctcgcgg cgctaattgg cggtgtactg gttggcggcg cactgggggc
     3901 gatcaacggc tgcctggtca actggacggg actacacccg ttcattatca cccttggcac
     3961 caacgctatt ttccgtggga tcacgctggt gatctccgat gccaactcgg tatacggctt
     4021 ctcatttgac ttcgtgaact tctttgccgc cagcgtaatt gggatacctg tccccgttat
     4081 cttctcgcta attgtcgcgc tcatcctttg gtttctgaca acgcgtatgc ggctcgggcg
     4141 caacatctac gcactgggcg gcaacaaaaa ctcggcgttc tattccggga ttgacgtgaa
     4201 attccacatc ctggtggtgt ttatcatctc cggtgtttgt gcaggtctgg caggcgtcgt
     4261 ctcaactgca cgactcggtg ccgcagaacc gcttgccggt atgggttttg aaacctatgc
     4321 cattgccagc gccatcattg gcggcaccag tttcttcggc ggcaaggggc gcattttctc
     4381 tgtggtgatt ggcgggttga tcatcggcac catcaacaac ggtctgaata ttttgcaggt
     4441 acaaacctat taccaactgg tggtgatggg cggattaatt atcgcggctg tcgcccttga
     4501 ccgtcttatc agtaagtaag gaattgaaca tgaaaatctc cccctcgtta atgtgtatgg
     4561 atctgctgaa atttaaagaa cagatcgaat ttatcgacag ccatgccgat tactttcaca
     4621 tcgatatcat ggacggccac tttgtgccga atctgacgct ctcaccgttc ttcgtaagcc
     4681 aggtaaaaaa actggcgagt aaaccgctcg actgccatct gatggtaacg cgtccgcagg
     4741 attacattgc tcaactggca cgtgcgggag ctgatttcat cactttgcat ccggaaacta
     4801 tcaacggtca ggcattccgc ctgattgatg aaatccgccg tcatggcatg aaagtggggc
     4861 tgattcttaa tccggaaacg ccggttgagg ccatgaaata ctatatccat aaggctgata
     4921 aaattacggt catgactgtc gatcccggtt ttgccggaca acccttcatt cctgaaatgc
     4981 tggataaagt tgccgaactg aaggcatggc gtgaacgaaa agatctggag tacgaaattg
     5041 aggtggacgg ttcctgcaac caggcaactt acgaaaaact aatggcggca ggggcggatg
     5101 tctttatcgt cggcacttcc ggcctgttta atcatgcgga aaatatcgac gaagcatgga
     5161 gaattatgac cgcgcagatt ctggctgcaa aaagcgaggt acagcctcat gcaaaaacag
     5221 cataacgtcg tagcgggcgt ggatatgggg gcaacgcata tccgcttttg tctgcggaca
     5281 gcagaaggtg aaacgctaca ctgcgaaaaa aagcggaccg cagaagttat tgctcccgac
     5341 ctggtgtcgg gtatcggcga aatgattgac gagcaactca ggcgctttaa cgctcgctgt
     5401 catggtctgg tgatgggatt tccggcgctg gtcagtaaag ataaacgcac cattatttct
     5461 acgcctaacc tgccgttaac agcggcagat ttatatgatc tcgccgataa gctcgaaaat
     5521 acgctgaatt gtccggttga gttttcccgc gacgttaacc tgcaactttc ctgggacgta
     5581 gtagaaaacc gccttacgca acaactggtt ctggcggcct atctcggtac ggggatgggg
     5641 ttcgcagtgt ggatgaacgg tgcgccgtgg acgggtgcac acggtgtggc aggcgaactg
     5701 ggccatatcc ccctgggaga tatgacccaa cactgcgcgt gtggcaattc tgggtgcctg
     5761 gaaaccaatt gctctggaat ggcgctaaga cgctggtacg aacaacagcc ccgaaattac
     5821 ccattgagcg atcttttcgt ccatgcggaa aacgcccctt tcgtccagag tctgcttgaa
     5881 aacgcggcac gagccattgc caccagcatt aatctgttcg atcccgatgc ggtgattctg
     5941 ggcggtggcg tgatggatat gcccgccttc ccacgcgaga ctctcattgc catgacccaa
     6001 aagtacctgc gccgtccact gccgtatcag gtcgtgcgct ttattgccgc ctcatcttct
     6061 gactttaatg gcgctcaggg tgcagcaata ttggcgcatc aacgtttttt gccacagtcc
     6121 tgtgctaaag tcccatgagt aaagcgttgg cacagtagcg caatgtcccg ctgtgccaac
     6181 gacaggtaca atatatataa taattacata aaacagccca tattattccc agcaatgata
     6241 gttctactgt aattttccct cttcagcaca aatgcctaat aaaatggctc gttccgctca
     6301 cacttccact tattaaagtc gcaaattccc aattatgata acgccagctt taaatgacgt
     6361 att
//
LOCUS       DAFGPF010000196         6179 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFGPF010000196 DAFGPF010000000
VERSION     DAFGPF010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6179
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.196"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..764)
                     /gene="reiD"
                     /locus_tag="LSX49_004927"
     CDS             complement(<1..764)
                     /gene="reiD"
                     /locus_tag="LSX49_004927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol utilization transcriptional
                     regulator ReiD"
                     /protein_id="HBL7171195.1"
                     /translation="MAYVSQVSESNGPYVRFMHMHPQTVELILITEGDGEYFIGDRIY
                     PVRKGDLVIYNSQVVHDEYLESGRPIGTICCGINNISCPGLRENALIPDDIVPVIPLY
                     HHYATVEKLMSSVFTVINQHAVEGPAMAQLLTQVVLKYIEGNVLLRTGNDAIQRHENL
                     LDSIKSYIDRNFYEPIRLDTLATKFNVSPYYVSHEFKRRYGYSPMDYLIKRRLGEAQS
                     LLTTDKGGREKITSIAYRVGFSNLSHFQNYFKNKVG"
     gene            881..1183
                     /locus_tag="LSX49_004928"
     CDS             881..1183
                     /locus_tag="LSX49_004928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171196.1"
                     /translation="MKQKCYIDHNFFQTFPHHNKQPLISHQIKTIKINKLIGFLISYC
                     TYPRIKISRQIFKIKFHKNRFEIFNPKIYIEYGMRFRLKITRLSCDRSVRTSSTSV"
     gene            1199..2704
                     /gene="iolA"
                     /locus_tag="LSX49_004929"
     CDS             1199..2704
                     /gene="iolA"
                     /locus_tag="LSX49_004929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate-semialdehyde dehydrogenase IolA"
                     /protein_id="HBL7171197.1"
                     /translation="METVGNFIHGKTTLSSSGETLPVANPATGKVIRQVTQSTREEML
                     AAIQSAHEAFPAWSKMTPLRRARILFEFKVLLEKHRDELAALIVSEHGKVWSDALGEL
                     TRGIEVVEFACGIPHLSKGEYSFNVGSGVDSFSLMQPLGVVAGITPFNFPAMVPMWMF
                     PVALACGNTFVLKPPALVPSASLRMAQLLQEAGLPDGVFNVVHCGNEAASLLTSDPRV
                     QAVSFVGSSAVAEHIYTTASAHGKRVQAFGAAKNHAIVMPDADLDATVNAIMGGAFGS
                     AGERCMALPVVVAVGDETADRLIERLKPLIAALRIGPGELRGKDENEMGPVVSRAHQQ
                     KVLGYIDKGVSEGATLVMDGRNYSVAGYPEGFYVGGTLFDNVTPEMTIWREEIFGPVL
                     GIVRVPDYATAISTVNSHEFGNGSVIFTTNGHYAREFAQSVEAGMVGINIPVPVPMAF
                     HSFGGWKRSVFGALNVHGPDGVRFYTRMKTVTSRWPNGQQIVSEFSMPTLG"
     gene            2729..3538
                     /gene="iolB"
                     /locus_tag="LSX49_004930"
     CDS             2729..3538
                     /gene="iolB"
                     /locus_tag="LSX49_004930"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HBL7171198.1"
                     /translation="MANLLSTCTSESGNIQHISPQNAGWEYVGFDVWQLKAGESITLP
                     SDERERCLVLVAGLASVKAADSFFYRIGQRMSPFERIPAYSVYLPHHTEAKVTAETDL
                     ELAVCSAPGFGELPVRLISPQEVGVEHRGKGRNQRLVHNILPDSQLADSLLVVEVYTN
                     EGDTSSWPAHKHDTAVEGQETYLEETYYHRFNPPQGFCLQRVYTDDRSLDECMAVYNR
                     DVVKVPKGYHPVATIAGYDNYYLNVMAGPLRKWRFTWEENHAWINSPDYPR"
     gene            3731..4162
                     /gene="tnpA"
                     /locus_tag="LSX49_004931"
     CDS             3731..4162
                     /gene="tnpA"
                     /locus_tag="LSX49_004931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL7171199.1"
                     /translation="MGDEKSLAHTRWNCKYHIVFAPKYRRQAFYGEKRRAVGSILRKL
                     CEWKNVRILEAECCADHIHMLLEIPPKMSVSSFMGYLKGKSSLMLYEQFGDLKFKYRN
                     REFWCRGYYVDTVGKNTAKIREYIKHQLEEDKTGSPFTGRK"
     gene            complement(4574..6010)
                     /gene="iolT2"
                     /locus_tag="LSX49_004932"
     CDS             complement(4574..6010)
                     /gene="iolT2"
                     /locus_tag="LSX49_004932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol import MFS transporter IolT2"
                     /protein_id="HBL7171200.1"
                     /translation="MSQRSKYNSAYVYVLCCIAALAGLMFGYSTAVITGVVLPLQQYY
                     QLTPTETGWAVSSIVIGCIIGALVGGKIADKLGRKPALLIIAIIFIASSLGAAMSESF
                     MIFSLSRIVCGFAVGMAGTASTMYMSELAPAEIRGKALGIYNISVVSGQVIVFIVNYL
                     IAKGMPADVLVSQGWKTMLFAQVVPSIAMLAITLFLPESPAWCARNNRSEARSIKVLT
                     RIYSGLTATDVAAIFDSMKETVRPQDNVAGGERTNLKSSPVLRYILLVGCCIAVLQQF
                     TGVNVMNYYAPLVLQNSSTEVVMFQTIFIAVCNVVGSFIGMILFDRYGRIPIMKIGTI
                     GSIVGLLIASYGLYTHDTGYITIFGILFFMLLFAVSWSVGAWVLISEVFPEKIKGFGM
                     GLAVSLMWIANFLISLLFPVINDNAWLQETFGGAFSMWIFVVFNLVCYIFISRYVPET
                     KGVPLTEIERLAENKLREIQGKRRDVIA"
BASE COUNT         1667 a         1536 c         1518 g         1458 t
ORIGIN      
        1 ttccccactt tatttttgaa gtaattctga aaatgactaa ggttgctaaa gccaacacga
       61 taggcaatag aggtgatctt ttcgcgcccg cctttatccg tggttagtaa cgattgcgcc
      121 tcccccagcc tacgttttat caggtaatcc atcggtgaat aaccatagcg gcgtttaaat
      181 tcatgggaaa cataataagg actgacatta aatttcgtcg ccagtgtatc cagccgaatt
      241 ggctcataga aattgcgatc aatataggat tttattgaat caagtaaatt ttcatggcgc
      301 tgtatggcat cgttacctgt gcgcaataag acatttccct caatgtattt gagtactacc
      361 tgggtcaata gctgcgccat tgctggccct tccaccgcat gctgattaat aacggtaaac
      421 acggagctca tcagtttttc caccgtcgca taatggtgat acagtggaat aaccggcaca
      481 atatcatccg gtattagcgc attctcacgt agacccggac acgaaatatt gttaatccca
      541 caacaaatag tgccaattgg ccgcccgctt tccagatact catcatgcac cacctggctg
      601 ttataaatga ccaggtcgcc tttacgaacc gggtagatgc gatcgccaat gaaatactcc
      661 ccgtctcctt cggtgataag aatcagttca acggtctgtg ggtgcatatg catgaaccgg
      721 acatacggac cattgctctc actgacctga ctcacatacg ccaactgggg cttattctct
      781 cgttctgaag gacagaagca caagcgcatg atttaccctc caatatccga aactgtggtg
      841 ccgaaacacc cctgaaattt gaatttttat actacaccaa atgaaacaaa aatgctatat
      901 agatcataat tttttccaaa cctttcctca tcacaacaaa caaccattga tatcacacca
      961 aataaaaaca ataaaaatca acaagttaat tggatttttg atttcttact gcacataccc
     1021 tcgtataaaa atcagtcgtc aaattttcaa aataaaattt cataaaaata gatttgaaat
     1081 ttttaatcct aaaatttaca ttgaatacgg tatgcgtttt aggctgaaga taaccaggct
     1141 ttcctgtgac cgctcagtca gaacgtcgtc aacatcggtt taagaggata aaaaagagat
     1201 ggaaacagtc ggcaatttta ttcatggtaa aacgacactg agcagcagcg gcgagacgct
     1261 accggtggct aatccggcca ccggtaaagt aattcgtcag gtcacccaga gcacccgaga
     1321 ggagatgctg gcggcaattc aaagcgcaca tgaggctttt ccggcatgga gtaaaatgac
     1381 tccgctacgc cgggcacgta tcctttttga attcaaagta ttactggaaa agcatcggga
     1441 cgaactggcg gcgctgatcg tcagcgagca tggcaaggtc tggtcagatg cgcttggcga
     1501 actgacgcgc ggcatagagg ttgtcgaatt tgcctgcggg atcccgcatc tcagcaaagg
     1561 agagtactcc tttaacgtcg gctcaggcgt tgacagcttt tcattaatgc agccgcttgg
     1621 ggttgtggca ggcatcacac cgtttaactt cccggcaatg gtgcctatgt ggatgttccc
     1681 ggttgctctg gcttgcggca ataccttcgt cctgaagccg cccgcactgg tgccgtccgc
     1741 atcgttacgt atggcgcagc ttctgcagga ggctggcctg ccggacggcg tgtttaacgt
     1801 tgttcactgt ggcaatgagg cggctagcct gttgaccagc gaccctcgcg tacaggccgt
     1861 cagctttgtc ggttcctccg ccgtcgcgga acatatctat accaccgcca gcgcccatgg
     1921 caaacgcgta caggccttcg gggccgccaa aaatcacgca atcgtcatgc cggatgcaga
     1981 tctggacgcc accgtcaacg ccattatggg cggagcattt ggttccgcgg gcgaacgctg
     2041 tatggcgctg ccggtagtgg tcgcggtggg cgatgaaacg gcggaccgtc tgatcgaacg
     2101 cctgaaaccg ctgattgcgg cgctacgtat cggcccggga gagctgcgcg gcaaagatga
     2161 aaatgaaatg ggcccagttg tttcacgtgc tcatcaacag aaagtgttgg gttacatcga
     2221 caaaggggtt agcgagggag caactctggt catggatggc cgcaactata gcgtggcggg
     2281 atatcctgaa ggcttttatg tcggcggcac tctgtttgat aacgtcacgc ctgagatgac
     2341 catctggcgt gaagaaattt ttggcccggt tctcggaatt gtgcgcgtcc cggattatgc
     2401 caccgccatt agcacggtaa actcccatga attcggcaac ggcagcgtga ttttcaccac
     2461 caacggtcac tatgcgcgcg aattcgccca gtcggttgaa gccgggatgg tcggtattaa
     2521 tattccagtt ccggttccga tggcatttca ctcttttggc ggctggaagc gctcggtgtt
     2581 tggcgccctg aacgtccatg ggccggatgg cgtgcgcttc tatacccgga tgaaaaccgt
     2641 tacctcgcgt tggccgaacg gacagcagat cgtatcggag ttcagtatgc caactctcgg
     2701 ttaatacgct ttcaggaagg agaagattat ggccaacttg ctgagtacct gtacctctga
     2761 gtcgggaaat atccaacaca tttcccctca aaatgcaggc tgggagtatg tcggttttga
     2821 tgtctggcag ttgaaggctg gagagtcgat aaccctgccg tccgatgagc gtgaacgctg
     2881 tctggtgctg gttgccgggc tggccagcgt taaggccgcc gacagttttt tctatcggat
     2941 tggtcagcgc atgagtccgt ttgaacgcat tccagcttat tcggtttacc tcccccatca
     3001 tacggaggcg aaagtgacag ccgaaaccga ccttgagctg gccgtatgca gcgcgccggg
     3061 attcggagag cttccagtac gtctgatctc gccacaagag gtcggggtag agcatcgggg
     3121 aaaagggcgc aatcagcgcc tggtgcataa catccttcct gatagccagc tcgccgacag
     3181 cctgctagtc gttgaagtgt acactaatga aggcgatacc agctcctggc ccgcacacaa
     3241 gcacgatacg gcagttgaag gccaggagac ctatctggaa gagacatact atcaccgttt
     3301 caatccacct cagggattct gcttacagcg cgtctacacc gacgatcgca gcctggatga
     3361 atgtatggcg gtctataacc gggatgtagt gaaagtacct aaaggctacc acccggttgc
     3421 caccatcgcg ggttacgata actactatct gaacgtgatg gccggcccgc tacgaaaatg
     3481 gcgtttcacc tgggaagaga accacgcgtg gattaactca ccagactacc cgcgataaca
     3541 cttcgttgag tggtactttg ccagccgtcc tctgcggctg gcttttttgt ctatgccccc
     3601 ccccagctag gctggggggg ccggaaagct ttcagcttta agccagttat taaaacccct
     3661 tttgatttgt taaaacatct tgcggtctgg caactgcaaa agttcaacaa gaaatcaaaa
     3721 gggggtccca atgggggacg aaaagagctt agcgcacacc cgatggaact gtaaatatca
     3781 catagttttc gcgcccaaat accgaagaca agcgttctat ggagagaagc gtagggcagt
     3841 aggcagcata ttaagaaaat tgtgtgaatg gaaaaacgta cgaattctgg aagcggaatg
     3901 ttgtgcagat catattcaca tgcttctgga gatcccgccg aagatgagtg tgtcgagctt
     3961 catggggtat ctgaagggta aaagtagtct gatgctttac gagcagtttg gggatctaaa
     4021 attcaaatac aggaacaggg agttctggtg cagagggtac tatgtcgata cggtgggtaa
     4081 gaacacggcg aagatacggg aatacataaa gcaccagctt gaagaggata aaacgggcag
     4141 cccgtttacg ggccgtaagt aacgaagttt gatgcaaatg tcagatcgta tgcgcctgtt
     4201 aggacgcggc tggtaagaga gccttacagg cgcatcagaa aaacctccgg ctatgccgga
     4261 ggatatttat tattcaactc tgcgccacac acgctcataa gatcgctatc caccttctct
     4321 aaaattattt ccctgttttg tatatagcgt atttacggca cggcccccac caggaatacg
     4381 caataaaata atgatgcaga agaagactta ccctatttgc cgatattatt atggatcaat
     4441 tagttacata gaggtggtaa acactgggga ggtttcaaca gggtatatcc tgtgcgcact
     4501 cgctggaggg agtaaaggtt gtgtaaccag cggagaatat ctctggatat tctccgctaa
     4561 tattggagag gtatcaggct attacatcgc gacgtttccc ctgaatttca cgcagcttgt
     4621 tctcggccag ccgttcaatt tctgttagcg gcaccccttt tgtttccggc acataacgag
     4681 aaataaagat atagcagacc aaattaaaga cgacaaaaat ccacatcgag aaagcgccgc
     4741 cgaaggtctc ctgcagccag gcgttatcat ttatgaccgg gaacaacagt gagatgagga
     4801 agttggctat ccacatcaga ctcaccgcca gccccatccc aaaacctttt atcttttcag
     4861 ggaaaacctc agaaatcagt acccatgcgc caacgctcca gctgacggca aacagcagca
     4921 taaaaaacag gatgccaaag atggtaatgt agcctgtatc atgggtgtac aaaccgtatg
     4981 acgcgatcaa caggccgaca attgagccga tggtaccaat tttcataatc ggtatacggc
     5041 catagcggtc gaacaggatc atgccgataa aactgcccac cacattacat accgcgataa
     5101 aaatggtctg gaacataacc acttcggtac tgctgttctg caacaccagc ggcgcataat
     5161 agttcattac gttaacgcct gtgaactgtt gcaaaacggc gatacagcat ccaaccaaca
     5221 gaatatagcg gagcaccggc gagcttttca ggttggtgcg ttctcccccg gcgacgttgt
     5281 cctgtggacg tacggtttct ttcatgctgt caaaaatagc ggccacatct gtggccgtta
     5341 atccactgta gatccgggta agcaccttta tcgaacgggc ttcgctgcgg ttgttacggg
     5401 cgcaccatgc cggtgattcg ggtaggaaaa gcgtaatcgc taacatcgca atggagggta
     5461 ccacttgggc aaaaagcata gtcttccagc cctgggaaac caacacatca gcaggcattc
     5521 cttttgctat cagatagttg actataaaca cgataacctg gccagatacc acggaaatat
     5581 tgtaaatgcc cagcgctttg ccgcgaattt cagcaggcgc cagttcagac atatacatgg
     5641 tggatgccgt tccggccatc ccaaccgcaa aaccacacac aatgcgggaa agggagaaga
     5701 tcatgaacga ttcactcatc gccgccccta aggaagaagc gataaaaatg atcgcaatga
     5761 tcagaagcgc aggtttacgc cccagtttat cggcaatttt tccaccgacc agcgcgccga
     5821 tgatacaacc aatcacgata ctggaaacgg cccatccggt ctcggttggc gtcagttggt
     5881 aatactgctg taaaggcaat actaccccgg taatcaccgc cgttgaataa ccaaacatca
     5941 atccagccag cgccgcaata caacacagga cgtacacata ggccgaattg tacttacttc
     6001 tctgagacat aatccctccc ttgcctgttg aggaaacaac acactaatga aattattcat
     6061 tttatttttg cattcattag aagaaaaatt ccatgcaaaa gttcacgaaa tggagatgtt
     6121 ccaggaaaga acaaaaagta cagcccctga caaattgagt tcaggcactg tcacgaaag
//
LOCUS       DAFGPF010000197         6119 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFGPF010000197 DAFGPF010000000
VERSION     DAFGPF010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6119
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.198"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..427
                     /locus_tag="LSX49_004933"
     CDS             <1..427
                     /locus_tag="LSX49_004933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL7171201.1"
                     /translation="KCLKRGDTLVVWKLDRLGRRMKHLIALTEELRAKGVNFRSLTDS
                     IDTSTPMGRFFFHMMGALAEMERELIVERTLAGLAAARAQGRVGGRRPKLTKEQHEQI
                     ARLLQKGYDRKRLAIIYDIGLSTIYRYHPVGTVITQPEM"
     gene            complement(683..1966)
                     /gene="aroA"
                     /locus_tag="LSX49_004934"
     CDS             complement(683..1966)
                     /gene="aroA"
                     /locus_tag="LSX49_004934"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL7171202.1"
                     /translation="MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAESARELFLGNAGTAMRPL
                     AAALCLGSNDIVLSGEPRMKERPIGHLVDALRQGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIRGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPEKLKFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQPG"
     gene            complement(2037..3125)
                     /gene="serC"
                     /locus_tag="LSX49_004935"
     CDS             complement(2037..3125)
                     /gene="serC"
                     /locus_tag="LSX49_004935"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HBL7171203.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMSEWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNDSMFNTPPTFAWYLSGLVFKWLKANGGVAAMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            complement(3324..4016)
                     /locus_tag="LSX49_004936"
     CDS             complement(3324..4016)
                     /locus_tag="LSX49_004936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBL7171204.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMNAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            4146..5906
                     /locus_tag="LSX49_004937"
     CDS             4146..5906
                     /locus_tag="LSX49_004937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     accessory protein YcaO"
                     /protein_id="HBL7171205.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTIYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWSFSGTTEEEFATLMAIFKKEDKEVYIADYEHLGVYSCRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
BASE COUNT         1607 a         1517 c         1438 g         1557 t
ORIGIN      
        1 aaagtgcctt aaaagagggg atacattggt ggtctggaag ctggatcggt tgggtagaag
       61 aatgaaacac ctcattgctc tcacagaaga gctacgcgca aaaggtgtca attttcgcag
      121 tctgacggat tcaatcgata ccagcactcc gatgggaagg ttcttttttc atatgatggg
      181 tgcactggca gaaatggagc gtgaactgat agttgagcgc acgctggctg gactggctgc
      241 tgcgcgagca caaggaagag ttggaggacg tcgcccgaaa ctgacgaagg agcagcatga
      301 gcagatcgca agattgctcc agaaagggta tgacagaaag cggctggcaa ttatctatga
      361 tattggactg tcaacgatct accgctatca ccctgttggg actgtcataa cgcaacctga
      421 aatgtaattc tttttcaaat aatgaaacgc cgcgtggatg ccatttatcg cacaagatag
      481 agtgcattta tcgcgcggcg catcattctt catgtgaatc atccgttgat taattatata
      541 taaacattat gtatcaacaa gttacattga taattaacgc taccattaat aaaaataccc
      601 cacaaggtcc gaaaaaaaac gccggcaatg tgccgacgtc tttgaaaaga aaggattgtc
      661 tatgttatcg cccgttattc attcagccgg gttgacttat ccgcgccaat tgctcgaaat
      721 agtctggaaa agttttagcg gtacattttg gatcaagaat cgtcacaggc gtatctgata
      781 atgcgaccag cgagaaacac atcgccatcc ggtgatcatt ataagtggcg atctcagcaa
      841 atttcagttt ttccggtggc gtaatgcgaa tgaaatcatg cccctcttcg acttccgcac
      901 cgactttacg cagttctgtt gccatcgcaa acaggcgatc ggtctcttta acacgccagt
      961 tatagatatt gcgcagcgtg gtggtgcctt ttgcaaataa cgccgcggtg gcaatggtca
     1021 tcgccgcatc gggaatatgg ttcatatcca tatcaatggc gttcagttca ccacgcgtgc
     1081 aggaaatata atcatcgccc cagcaaatgg tcgcgcccat tttttccaga acatcagcaa
     1141 agcgaatatc accctgcata ctgttgcgtc caatgccggt cacttttaca gtgccgcctc
     1201 tgattgctgc tgctgccagg aaataagaag ccgaagatgc atcgccttca accaaataag
     1261 tgcccggaga ctggtaagac tgcccccctt ttacgacaaa ttgttgatag tgctgatttt
     1321 caatttcaac accaaacgtc ttcatcagat tgagggtgat atcgatataa ggtttagaaa
     1381 ccagatcgcc tttaatacga atcaccgtat cttccggcgc aagaggcgca gtcattaaca
     1441 gtgcggtgag gaactggctg gaaacggagc catcaacatc aacgttgccg ccagtaaagc
     1501 cgccctgtaa acgcaatggc ggataatttt cttgttccag gtaagtgatc ttcgccccgc
     1561 cctggcgcag cgcatccacc agatgaccaa tcgggcgttc tttcattcgc ggttcaccgc
     1621 tcagtacaat atcattgcta cccaggcaaa gtgctgccgc cagcggacgc attgccgttc
     1681 cggcgttacc gaggaacaac tcccgggcac tttctgcgtg taatggacca ccgttaccga
     1741 taatttcgca acgcgtacga tcggctgaaa gcgtatagct tacccctaac gctgttaatg
     1801 cattcagcat atggcgcacg tcatcgctat ccagcagatt ggttaatact gttttgccgt
     1861 gtgctaatgc cgccagcaat aaagcgcggt tagaaacgct cttggaaccg ggcagattaa
     1921 tagtgccatc gacacgagcg atgggttgta acgttaggga ttccatgaac tcaactctct
     1981 acaacagaaa taaaaacccc acaggctggc tgtggggatt atgcaaaatt tcgacattag
     2041 ccgtgacgac gttcgaactc aaccatgaag tctgtcagtg ctttaacacc ttccagcggc
     2101 atggcgttat aaatagacgc acgcattccg ccgaccactc ggtgaccttt cagcgcatgt
     2161 aagcccgcag cgaaagactc ttcgaggaac aatttatcaa gcgcgctatc cgccaactgg
     2221 aacggcacgt tcatccgcga acggttagct ttcgccacat cattgcggta gaaatcgctg
     2281 ttatcaatca ccccatacag cagttctgct ttttgctgat tgatcttatc cattgcagcc
     2341 acaccgccgt tcgctttcag ccatttgaag accaggccag ataagtacca ggcaaatgtc
     2401 ggcggcgtgt tgaacatgga atcgttatcg ttgaggatgg agtaatccag aatcgatggg
     2461 caggcgatat tcgctttgcc cagcaaatct tcacgaacga tgacgattgt caggccagcc
     2521 gggccgatat ttttctgcgc gccagcgtaa attacaccat aacggctgac atcaatcgga
     2581 cgggaaagaa tggttgaaga gaagtcagcg gcgaccacca cgtctttacc gaagtctggt
     2641 gtttcatcga tagcgatacc atcgatggtt tcgttcgggc agtaatgcat ataagcagca
     2701 ttatcagaga gttgccattc actcattggc ttaactgcgc gaagaccatc aacggtcact
     2761 ttcgcatcaa acacatttgg tgtgcagtat tttttcgctt ctttgatagc acttgctgcc
     2821 cagtaacccg catcaacata atctgcagtg gttttatcac caagaatatt caacggtact
     2881 gcagcaaatt gaccgcgacc accgccatgg cagaacaata ctttgtagtt ggaggggacg
     2941 ttaagaagat cgcgaaaatc cttctcggct tcctctgcaa cctgaatgaa ctctttgcca
     3001 cggtgactca cttccatcac cgacgtacca agaccgttcc agtcgcgcag ttcctgttga
     3061 gcctgtttaa gcacctctgc cggtagcatt gccggaccag aactaaaatt gaagatttga
     3121 gccatttccc ctcaccacgt tgcgttgcta ttaacccgcg gtcaatcgat tgcgaccaca
     3181 ggtaatacat tattccagtg gctatcggtt ttatcattca gtgacacaca tcgcaatgag
     3241 taaaaccgtt gagggcaaaa atgtggcttg catcacacaa aagaatctct cggattatta
     3301 gcaaaaagcc gatgtttttg ctgtcaggtc acccgtttag ctcgacttgc cttcgtccat
     3361 tctggatttg cacagcgcgg acataattgt ttttcccccg cgttcatatg aatgatttca
     3421 ctgcaacgga tgcaggcata gtccgccgac tccggcacca ctttgtaacg ctgagtacag
     3481 tcactgggta aaataagtaa ccccggtttc accttgtcat cttcaaagaa ataaacactg
     3541 atttgcccgt tggtttcgag aatcgccaga cgtacctgcc ccaactgctc tacaccgcgc
     3601 aatcgtagct ccataaagaa ctcaaattcc gtcatgttgg agttattgag tttcgaccag
     3661 gccagctcgc cgtcttcaat aatgacaacc ggcttgcctt ccagaagatc ttccagtttt
     3721 tcactgtgcg ccatcaacca cattaccagg cggtataaca acgccagagt aataaagacg
     3781 ataagtaccg ggaccatcgg cacatcatca taaaacgcca catctcccgc cgctgaaccc
     3841 agtgtcagaa tgattaacac ttcaaacagc gacatctgcc gcacaccgcg tcttccggtc
     3901 attttgagga acaaaaaaac cagtacaaag gtataaagac tacgtagtgc aacttcgcca
     3961 aggaaatcaa aaggcacttt atcaaatgcc atacggtgga gatcgaacgc cttcattttt
     4021 atgctcttat cgtggtttat ccgctaaaag catagccaac agttcatcgg catggcggcg
     4081 gtgatagcgc ctttgagata aaacccgtat tattgcgcgc tttccgtacg actaaagtga
     4141 ttttcatgac gcaaacattt atccccggca aagatgccgc tctggaagat tccatcgctc
     4201 gcttccagca aaaactttca gacctcggtt ttcagattga agaggcctcc tggctgaatc
     4261 ccgtgcctaa tgtctggtct gtacatattc gcgacaaaga gtgcgcactg tgttttacca
     4321 acggtaaagg cgcaaccaaa aaagcggcgc tggcttctgc cctcggtgaa tatttcgagc
     4381 gtctctcaac caactacttt tttgcggact tctggctggg cgaaaccatc gccaacggcc
     4441 cattcgtgca ttatcccaac gaaaaatggt tcccactgac cgaaaatgac gatgtaccag
     4501 aagggctgct cgatgaccgt ctgcgcgcat tttacgatcc ggagaatgaa ctgaccggta
     4561 gtatgctgat tgacctgcaa tccggtaacg aagatcgtgg tatttgcggt ctaccgttta
     4621 cgcgccagtc cgacaatcag accatttata ttccgatgaa tatcattggt aacttgtacg
     4681 tttctaacgg tatgtctgct ggcaataccc gtaacgaagc acgcgttcag gggttatccg
     4741 aagttttcga acgttacgtg aaaaaccgca ttattgctga aagcatcagc ttgccggaaa
     4801 tcccggcaga cgtgctggca cgttatccag cagtagttga agcgatcgaa acgctggaag
     4861 cggaaggttt cccgatcttc gcttatgacg gttcgcttgg cggccagtat ccggtgattt
     4921 gcgtggtact gttcaatcct gctaacggta cctgctttgc ctcattcggt gcgcatcctg
     4981 attttggcgt tgcactggaa cgtaccgtga ccgagttgct gcaaggtcgt ggcctgaaag
     5041 atctggatgt gtttactcca ccaaccttcg atgatgaaga agtcgctgaa cataccaacc
     5101 tcgaaacgca ctttatcgat tccagcggtt taatctcctg ggacctgttc aagcaggatg
     5161 ccgattatcc gtttgttgac tggagcttct ccggcaccac ggaagaagag ttcgccacgc
     5221 tgatggctat cttcaaaaag gaagataaag aagtttatat tgccgattac gagcatctgg
     5281 gtgtctactc ttgccgtatt atcgtacctg gcatgtccga tatttatccg gctgaagatc
     5341 tgtggttggc gaataacagt atgggcagcc atttacgtga aacgattctg tcactgcccg
     5401 gtagcgagtg ggaaaaggaa gattacctga acctcatcga gcaactggat gaagaaggtt
     5461 ttgatgactt tacccgcgtg cgtgaactgt tgggcctggc gaccgggtcg gataacggct
     5521 ggtacactct gcgtatcggt gaattaaaag ccatgctggc gctggctggt ggcgatctgg
     5581 aacaggctct ggtctggacc gaatggacga tggagtttaa ctcatcagta ttcagcccgg
     5641 aacgcgccaa ttattatcgc tgcctgcaaa cattgttatt actggcgcag gaagaagatc
     5701 gccagccgct gcaatatctg aatgcgtttg ttcgcatgta cggcgcagat gccgtggaag
     5761 ccgccagtgc agcaatgagc ggcgaagcgg cgttttatgg cttgcaacca gtagatagcg
     5821 atctgcacgc gtttgctgca catcagtcgt tgttgaaggc ctacgaaaag ctgcaacgcg
     5881 ccaaagcagc attctgggca aaataaaatc aaatagccta cgcaatgtag gcttaatgat
     5941 tcgtctgagt tatattacgg ggcgtttttt taatgccccg ctttacatat atttgcatta
     6001 ataaaataat tgtaattata aggttaaata tcggtaattc gtatttaata aatacgatcg
     6061 atattgttac tttattcgcc aggtgctccc ttttaattaa ctgttttagc ggaggatgc
//
LOCUS       DAFGPF010000198         5995 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFGPF010000198 DAFGPF010000000
VERSION     DAFGPF010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5995
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.199"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            152..1273
                     /gene="ompC"
                     /locus_tag="LSX49_004938"
     CDS             152..1273
                     /gene="ompC"
                     /locus_tag="LSX49_004938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HBL7171206.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNKSEDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLK
                     FQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
                     VDGLNFAVQYQGKNGSVDGEGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSSK
                     RTDDQNFGLNGYGERYLGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWA
                     NKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVINGRNYDDEDILKYVDVGATYYFN
                     KNMSTYVDYKINLLDDNRFTRDAGINTDDIVALGLVYQF"
     gene            1385..2440
                     /gene="apbE"
                     /locus_tag="LSX49_004939"
     CDS             1385..2440
                     /gene="apbE"
                     /locus_tag="LSX49_004939"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HBL7171207.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEA
                     MADIVTTSLRIGARTDGAMDITIGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSR
                     GMNGAGQPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDNF
                     KAWMSPQFKSFLISEKN"
     gene            2514..3578
                     /gene="ada"
                     /locus_tag="LSX49_004940"
     CDS             2514..3578
                     /gene="ada"
                     /locus_tag="LSX49_004940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HBL7171208.1"
                     /translation="MKYAIRLTDDQRWQSVLARDSNADGEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANASEALAAGFRPCKRCQPDKANPLQHRLDKITHACRLLEQETPVTL
                     EALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRELLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDD
                     DATLISELQQMFPAADSAPADLTFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIVIPCHRVVRGDGSLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            3578..4228
                     /gene="alkB"
                     /locus_tag="LSX49_004941"
     CDS             3578..4228
                     /gene="alkB"
                     /locus_tag="LSX49_004941"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HBL7171209.1"
                     /translation="MLDLFADAEPWQEPLAAGAVILHRFAFNAAEQLIRDINDVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHHLCQR
                     AATAAGYPDFQPDACLINRYVPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKVGGHPLTTDCRYNLTFRQAGKKE"
     gene            4304..5947
                     /gene="yojI"
                     /locus_tag="LSX49_004942"
     CDS             4304..5947
                     /gene="yojI"
                     /locus_tag="LSX49_004942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HBL7171210.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAVT
                     IWGGFILVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFSYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQNGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGQPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
BASE COUNT         1423 a         1504 c         1631 g         1437 t
ORIGIN      
        1 aatgaaacat cttaaaagtt ttagtatcat attcgtgttg gattattctg catttttggg
       61 gagaatggac ttgccgactg attaatgagg gttaatcagt atgcagtggc ataaaaaagc
      121 aaataaaggc atataacaga gggttaataa catgaaagtt aaagtactgt ccctcctggt
      181 cccagctctg ctggtagcag gcgcagcaaa cgctgctgaa gtttacaaca aagacggcaa
      241 caaattagat ctgtacggta aagtagacgg cctgcactat ttctctgaca acaagtcaga
      301 agacggcgac cagacctaca tgcgtcttgg cttcaaaggt gaaactcagg ttactgacca
      361 gctgaccggt tacggccagt gggaatatca gatccagggc aacagcgctg aaaacgaaaa
      421 caactcctgg acccgtgtgg cattcgcagg tctgaaattc caggatgtgg gttctttcga
      481 ctacggtcgt aactacggcg ttgtttatga cgtaacttcc tggaccgacg tactgccaga
      541 attcggtggc gacacttacg gttctgacaa cttcatgcag cagcgtggta acggcttcgc
      601 gacctatcgt aacaccgact tcttcggtct ggttgacggc ctgaactttg ctgttcagta
      661 ccagggtaaa aacggtagcg tagatggcga aggcatgacc aacaacggtc gtggtgccct
      721 gcgtcagaac ggcgacggcg ttggcggatc tatcacttat gattacgaag gcttcggtat
      781 cggtgctgct gtttctagct ccaaacgtac tgatgatcag aacttcggcc tgaacggtta
      841 tggtgagcgt tatttgggta acggcgaccg tgctgaaacc tacactggtg gtctgaaata
      901 cgacgctaac aacatctacc tggctgctca gtatacccag acctacaacg caactcgcgt
      961 aggttccttg ggttgggcaa acaaagcaca gaacttcgaa gctgttgctc agtaccagtt
     1021 cgacttcggt ctgcgtccgt ctgtagccta cctgcagtct aaaggtaaaa acctgggtgt
     1081 catcaatggt cgtaactacg acgacgaaga tatcctgaaa tatgttgatg ttggtgcgac
     1141 ctactacttc aacaaaaaca tgtccaccta cgttgactac aaaatcaacc tgctggacga
     1201 caaccgcttc acccgtgacg ctggcatcaa cactgatgac atcgtagctc tgggtctggt
     1261 ttaccagttc taatctcgat tgatatcgaa caaagggcct gcgggccctt ttttcattgt
     1321 tttcagcgta caaacacagt tttttggtgt actcttgcga ccgttcgcat gaggataatc
     1381 acgtatggaa ataagcttta cccgcgtggc actgctggct gccgcgctct tctttgttgg
     1441 ttgcgatcaa aaaccacaac ccgccaaaac ccacgctact gaagttaccg ttcttgaagg
     1501 caaaaccatg ggtaccttct ggcgtgccag catcccgggc attgacgcca aacgcagtgc
     1561 cgaacttaaa gaaaagattc agacccagct ggacgctgac gatcagctgc tttcgaccta
     1621 taaaaaagat tccgcgctga tgcgctttaa cgactcgcaa agtttgtcgc cgtggccggt
     1681 aagtgaagcg atggccgata tcgtcaccac ctcgctgcgc attggcgcaa ggaccgatgg
     1741 tgcgatggat ataaccatcg ggccgctggt gaatctgtgg ggctttggcc cggaacaaca
     1801 accggttcaa attccgagcc aggaacagat cgatgcgatg aaagccaaaa ccggcttaca
     1861 gcacctgacg gtcattaatc agtcgcatca gcaatatctg caaaaagacc tgccggattt
     1921 atatgtcgat ctctccaccg tcggcgaagg ttatgcggcg gatcacctgg cacgcttgat
     1981 ggagcaggaa gggatttccc gctatctggt gtcggtgggc ggcgcgctga acagccgtgg
     2041 tatgaacggt gcaggccaac cgtggcgggt agcgattcaa aaaccaaccg ataaagaaaa
     2101 cgcggttcag gccgtggtgg atatcaacgg tcatggtatt agcacctctg gcagctaccg
     2161 taactattac gaactggacg gcaaacgtct ttctcatgtt atcgatccgc aaaccgggcg
     2221 tcctatcgaa cacaatctgg tatccgtgac ggtgattgcc ccgacggcgc tggaggccga
     2281 tgcctgggat actggcttga tggtactcgg accggagaaa gccaaagagg ttgttcgccg
     2341 ggaaggactg gcggtctaca tgatcaccaa agagggcgat aattttaaag cctggatgtc
     2401 gccgcagttt aaaagcttcc ttatcagcga aaaaaattaa agcgcaagat tgttggtttt
     2461 tgtgcgatgg tgaccgggca gactaaaggc tatccttaac cagagagctg attatgaaat
     2521 acgccatacg cttaactgac gatcaacgct ggcaatctgt cttagcccgc gactcgaatg
     2581 ccgacggcga attcgttttc gccgtgcgca ccacgggtat cttttgccgt ccgtcttgcc
     2641 gagccagaca tgccttgcgg gaaaatgtct ccttctacgc aaatgccagc gaggcgcttg
     2701 ccgctggctt tcgtccctgc aaacgttgtc agccagacaa agccaatccc ctgcaacatc
     2761 gccttgataa aattacccac gcctgccgac ttctggaaca ggaaacgcct gtaacgctgg
     2821 aagccttagc cgaccaggtg gcgatgagtc catttcattt gcatcggttg tttaaagcga
     2881 ctaccggaat gacgcctaaa gcctggcaac aggcctggcg cgctcgccgt ttgcgcgaat
     2941 tgctggcgaa aggggagagc gtgactacat ctattcttaa cgccggattc cccgacagca
     3001 gcagttacta ccgcaaagcc gacgaaacgc tgggcatgac ggctaaacaa ttccgtcacg
     3061 gtggcgaaaa tctggcggtg cgttacgcgc tggctgattg tgagctgggc cgttgcctgg
     3121 tggcagaaag tgagcggggg atttgcgcga tattactggg cgatgatgac gcgacactaa
     3181 tcagcgagtt acagcagatg tttcccgctg ccgacagcgc gcctgctgat ctgacgtttc
     3241 agcaacatgt gcgtgaagtg atcgccagcc tcaatcaacg cgatacgccg ctgacgttac
     3301 cgctggacat tcgcggcact gcttttcagc aacaagtctg gcaggcactg cgcacgatac
     3361 cttgcggtga aaccgtcagt tatcagcaac tggctaacgc catcggcaaa ccgaaagcgg
     3421 tacgggctgt tgccagcgcc tgtgccgcca acaagctagc tatcgttata ccctgtcatc
     3481 gggtagtacg cggtgatgga tcgctttcag gttaccgctg gggcgtgtcg cgtaaagcgc
     3541 aactgctacg ccgcgaagct gaaaatgagg agaggtaatg ttggatctgt ttgccgatgc
     3601 tgaaccgtgg caagaaccac tggcggctgg agcggtgatt ttgcaccgtt ttgcttttaa
     3661 cgctgcggag caactgatcc gcgatattaa tgacgttgcc agccagtcgc cgtttcgcca
     3721 gatggtcact ccaggcggat ataccatgtc ggtggcgatg accaactgtg ggcatctggg
     3781 ctggacgacc catcggcaag gttatctcta ttcgcccatt gatccgcaaa caaataaacc
     3841 gtggcccgcc atgccgcaga gttttcatca tttatgtcaa cgtgcggcta cggcagcggg
     3901 ctatccagat ttccagccag atgcctgttt gatcaaccgc tacgttcctg gcgcgaaact
     3961 gtcgctgcat caggataaag acgaaccgga tctgcgcgcg ccaattgttt ctgtttctct
     4021 gggcttaccc gcgatttttc aatttggcgg cctgaaacga aatgatccgc tcaaacgttt
     4081 gttgttggaa catggcgatg tggtggtatg gggtggtgag tcgcggctgt tttatcatgg
     4141 cattcaaccg ttgaaagtgg gggggcatcc actcaccacc gactgccgct acaacctgac
     4201 attccgtcag gcaggtaaaa aagaataaaa ataagaatta ttattgctgt gcgcacgaag
     4261 atgtttaaac tgcgggctgt aattcattgt ccgggttttc tgcatggaac ttcttgtact
     4321 tgtctggcgg cagtatcgct ggccatttat cagtgtgatg gcgctaagcc tcgccagtgc
     4381 ggcattaggc attggcttaa ttgcttttat caatcagcgc cttatcgaaa cggcggatac
     4441 cagtctgctg gtattgccgg agtttctggg gttattgctg ctgttgatgg cagtcactct
     4501 cggatcgcaa ctggcgctca ccactttggg gcatcacttc gtttaccgac tgcgtagtga
     4561 atttatcaag cggattctgg atacccatgt cgagcgcatt gaacaacttg gtagcgcctc
     4621 gttgctggcg gggttaacca gcgatgtgcg caatatcacc attgcttttg tgcgtctgcc
     4681 ggaactggtg caggggatca ttctcactat cggttcagcg gcgtatttgt ggatgctgtc
     4741 gggcaaaatg ttgctggtaa cggctatctg gatggcagtc accatctggg gtggttttat
     4801 actggtggcg cgggtgtaca aacatatggc gaccctgcgt gaaaccgaag ataagctgta
     4861 cacggatttt caaaccgtac tcgaagggcg caaagagctg actctgaacc gtgaacgcgc
     4921 cgagtatgtg tttaacaacc tctacattcc tgatgcgcaa gagtatcgcc atcatattat
     4981 ccgcgcagac accttccatc ttagtgccgt gaactggtca aacatcatga tgctgggcgc
     5041 aatcggcctg gtgttctgga tggcgaacag tctcggttgg gctgatacca acgttgccgc
     5101 gacctattcg ttgacgttgt tattcctgcg tacgccgctg ctttcggcgg ttggcgcgtt
     5161 gccgacgcta ctgacggcgc aggtggcgtt taataagctg aacaaattcg cgctcgcgcc
     5221 tttcaaagca gagtttccgc gcccgcaggc gtttcccaac tggcaaacgc tggagctgcg
     5281 taacgtgacg tttagctatc aggataacgc gttttccgtt ggtccaatta atctcaccat
     5341 taaacgtggc gagctgctgt ttctgattgg tggcaacggt agtggaaaat cgacgctggc
     5401 gatgttgctg acgggcttgt accagccaca aaatggcgaa atcttgctgg atggcaaacc
     5461 tgtcagcggc gaacaaccgg aagattatcg aaaactgttt tcggcagtgt ttaccgatgt
     5521 ctggctgttt gatcaactgc tggggccgga ggggcaaccc gctaacccgc aactggttga
     5581 gaagtggctg gcgcagctga aaatggctca taagcttgag ttaagcaacg ggcgtattgt
     5641 taacctgaag ttatcaaaag ggcagaaaaa acgcgtggcg ctgttgctgg cgctggcaga
     5701 agaacgcgat attatcctgc tggatgaatg ggcggcggat caggatccac acttccgtcg
     5761 tgagttttat caggtgctgc tgccgctgat gcaggagatg ggtaaaacta ttttcgccat
     5821 cagtcatgat gatcattact ttatccacgc cgaccgcctg ctggaaatgc gcaacgggca
     5881 acttagcgag ctgacaggcg aagagcgcga tgctgcttcg cgtgatgccg ttgcccggac
     5941 agcataatat tacgacgctg acctggcgga ctgctgccgc caggtcaata ttcta
//
LOCUS       DAFGPF010000199         5988 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFGPF010000199 DAFGPF010000000
VERSION     DAFGPF010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5988
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.200"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(170..1582)
                     /locus_tag="LSX49_004943"
     CDS             complement(170..1582)
                     /locus_tag="LSX49_004943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL7171211.1"
                     /translation="MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQ
                     QAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDQVLDMLEAHS
                     DSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLML
                     DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIE
                     IPTDPETGISVEALELALEQWPIKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIV
                     IFEDDVYGELATEYPRPRTIHSWDIDGRVLLCGSFSKSIAPGLRVGWVAPGRYHDKLL
                     HMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIREYFPCEIC
                     ITRPKGGFLLWIELPEQVDMVCVARQLCRMKIQVAAGSIFSASGKYRNCLRTNCALPL
                     SETYREALKQIGEAVYRAME"
     gene            1759..1923
                     /locus_tag="LSX49_004944"
     CDS             1759..1923
                     /locus_tag="LSX49_004944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1127 domain-containing protein"
                     /protein_id="HBL7171212.1"
                     /translation="MEFYENKAKTPFIRLVQLWQAVRRWRRQMQTRRVLQQMSDERLR
                     DIGLRREDVE"
     gene            complement(1966..2304)
                     /gene="symE"
                     /locus_tag="LSX49_004945"
     CDS             complement(1966..2304)
                     /gene="symE"
                     /locus_tag="LSX49_004945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001534835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease SymE"
                     /protein_id="HBL7171213.1"
                     /translation="MTDTHSIALPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKG
                     QWLETAGFATGTAVDVKVMEGCIVLTAQPPAIEESELMQSLRQVCKLSVRKQRQVQEF
                     IGVISSKTPR"
     gene            complement(2519..5782)
                     /locus_tag="LSX49_004946"
     CDS             complement(2519..5782)
                     /locus_tag="LSX49_004946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBL7171214.1"
                     /translation="MSLSFSEAKLEQAIIELLQDQGYQHLIGDNVPRSSLDQVIIEDD
                     LRHYLAARYQPDGITEEEIQRLIKQFTTLPASDLYESNKTFCRWLANGFLFKRDDRQQ
                     KDLYIELLDTRHLPAALRQIFDAEDVPLQQAAELPPSYMNPPLNRIKIVNQLKISGKD
                     NQTRIPDGILYINGLPLVVFEFKSAVREQEASIGDAWKQLCKRYRRDIPQLFIYNALC
                     IISDGVNNRMGNLFAPYEYFYSWRKVTGNENREQDGIPSLHSMIQGLFHPVRLLDVIK
                     NFICFPDKAKHEVKICCRYPQYYAARKLYYSIKQARKPFGSGKGGTYFGATGCGKSYT
                     MQFLTRLLMKSVEFASPTIVLITDRTDLDDQLSAQMCNAKNYIGDDTIVPVTSREDLR
                     NQLAGRNSGGVFLTTIHKFTEDTELLSERNNIICISDEAHRSQVNLDQKVIVDKESGK
                     VRKTYGFAKYLHDSLPNATYVGFTGTPIDATLDVFGEVIDSYTMTESVQDEITVRIVY
                     EGRAAKVILDSSKLEEVEKYYEECANAGTNEWQIDESKKATATMNAVLGDEDRLKALA
                     EDFAKHYEKRVAEGSTVKGKAMFVCASREIAWDFYRQLKAIRPAWFEVKQAPDGVVLT
                     EQEQKELPPSEMVKMVMTRGKDDDEALYDLLGTKEYRKELDKQFKNAKSNFKIAIVVD
                     MWLTGFDVPELDTIYIDKPLQKHNLIQTISRVNRKLEGKSKGLVVDYIGIKSQMNQAL
                     AMYSRIDATNFEDIQQSVIEVKNHLDLLGQVFYEFDSRDYFSGEPQAQLSCLNRAAEF
                     VLRTQKVERRFMGLVKRMKAAYDVCCGSEALSQTERDYIHYYLAVRSIVFKLTKGDAP
                     DVTQMNARVREMIAEALKADGVEEIYFLGDKKAESIDIFDEDYLARINKIKLPATKIQ
                     LLQKLLEKAISDFKKVNQLQGINFTRRFQAIIDRYNERREDDVLNGEEFDTFSQEMTD
                     IIYDIKTEMGTWADLGIDIEEKAFFDILAHMRDKYQFTYDDEKMLSLAKEMKSVVDNT
                     SKYPDWSKRDDIKAKLKVELILLLHKHKFPPVANDDVYMGVLAQAENFKEHHMSSLN"
BASE COUNT         1475 a         1448 c         1456 g         1609 t
ORIGIN      
        1 tttaacttta aagattttgt agacctggta aggcgttcac atcgcatccg gtatgaacaa
       61 agcgcacttt gcctaagcca tgctggaacg tggcgattac cctgcaaaga taaaacgagt
      121 cacactctat tcgtgagagt aaatcaggcg cttcgccact atgtcgaatt tattccattg
      181 cccgatacac ggcctcgcca atttgcttca gtgcttcgcg ataggtttcg ctgagcggca
      241 aagcgcagtt ggtgcgcaga caattacggt atttgccgga agccgagaaa atcgagcctg
      301 ccgccacctg gattttcatg cggcacagct gccgcgcgac gcagaccata tcgacctgtt
      361 caggcaattc tatccacagt aaaaatccgc ctttcgggcg cgtaatacag atttcgcagg
      421 gaaaatattc ccgtatccag caggtataaa gtgccagatt gcgctgatag atctgccgca
      481 tccgccggat atggcgatga tagtgacctt ccagcacaaa cgttgccgcc gccatttgcg
      541 tggacggcac attaaagctg ctgatggcat atttcatatg cagcagttta tcgtgatagc
      601 gccccggtgc gacccagccc acgcgcaggc caggtgcaat acttttactg aacgagccgc
      661 acagcagcac tcgcccgtcg atatcccagg aatgaatggt ccgcgggcgc ggatactccg
      721 ttgccagttc accgtagaca tcatcttcaa aaatcacaat atcatgacgc tgagcgagag
      781 agagaacggc ccgtttgcgc gcgtccggca taataaatcc cagcggatta ttacagtttg
      841 gcaccagaat gatgccttta atcggccact gctccagcgc cagttccagc gcttcaacgc
      901 tgatgcctgt ttctggatcg gttgggattt caatcacttt cacgcccatg ccacgcagca
      961 tctgcatcga accgtaataa cagggggatt cgaccgcgac aatatcgccc ggtttacaca
     1021 ccgccattaa cgccagcgac atcgagttat ggcagccgct ggtaatgatg atgtcatcgg
     1081 cggtgactac cgagccgctg tcgagcatca ggcgggcaat ctgctctcgc aacactcgct
     1141 gaccggctaa caagtcataa ccgagaacgg tttgcagatt atgctgcacc acccggctta
     1201 gctcccgcca cagcggtttc aggctgggcg tttcgacatc cggcgtgctt ttgcttaacg
     1261 gaacaatgga actgtcgcta tgcgcctcca gcatatccag tacctgatcc cactgggtaa
     1321 tttccaccgg gcgctgcacc ggacgcgtca tcggcggcac tggcggctgg gctttacgtt
     1381 gtgcgacaaa ataccccgaa cgcggctgcg gagtgatgag cttcatcgtt tccagcgtct
     1441 ggtacgcctg ctgcacggtg ctgatgctga cgccgtgctc ctgacttaag ctgcgcaccg
     1501 acggcaattt ctccccgtga cgatacagcc cctgctcaat ccgctcggca agtagagtcg
     1561 ccagatgttg ataacgcgtc atgctgtatt ccttatttgg accatacaga gagaaaaacc
     1621 ggtacagatg aggctaaaaa accggatgca gatgctgttt taatctgtct gtatgttaaa
     1681 taaaactaat atttgcatct gtattgtgaa ctgccagaag acggatgatg aagcctctga
     1741 aagatgagga ggcagcagat ggaattttac gaaaacaaag ccaaaacgcc gtttatcaga
     1801 cttgtgcaac tctggcaggc ggtgaggcgt tggcggcggc aaatgcagac ccgacgagtg
     1861 ttacagcaga tgagtgatga gcggttgagg gatattgggt tacgcaggga ggatgtggag
     1921 tgagggggaa aattcccctt cccgtgtggg gaaggggaga gaaacttagc gtggcgtttt
     1981 gctactaatc accccaataa actcctgcac ctgcctttgt ttacgcaccg acagtttgca
     2041 cacctggcgc agtgactgca tcagttcgct ctcttcgatg gcgggtggtt gggcggtgag
     2101 gacaatacag ccttccatca ctttgacatc taccgccgtg ccggtggcaa aaccggcggt
     2161 ttccagccac tgacctttca gggtgatggc gggaatacgg ctgtaatccg ggtagcggct
     2221 cgcataactc acggttaatt gacggttatt tgccggggag acttctgctt caaacggtag
     2281 tgcaatagaa tgcgtgtcag tcataactgc tattccctat aaatagtgat tgtgatgagc
     2341 ggtgcgggtg tgcgccaaca catccgcatc gcgctaaata cctggatata tcatcagtaa
     2401 atatgggaaa agtccagcta aaaatagaaa ataataaaag cattactgga aagatctgga
     2461 agggaaatta acgttaattc agaatggccg gataacaaag tgtatccggc cttcataatt
     2521 aatttaaaga actcatatgg tgttctttaa aattctctgc ctgtgccagc acacccatat
     2581 aaacatcatc attcgctact ggcgggaact tatgcttgtg tagaagcaga ataagttcaa
     2641 ctttcagttt cgctttaata tcatcgcgtt tactccagtc aggatattta gatgtgttgt
     2701 caaccacgct tttcatctct tttgccagtg acagcatttt ttcatcgtca taggtgaact
     2761 gatatttatc gcgcatatga gcaagaatgt cgaaaaaggc tttttcttca atatcaatgc
     2821 ctaaatcggc ccaggtgccc atttcggttt taatatcata gataatatcg gtcatttcct
     2881 gactgaatgt atcgaattct tcaccgttga gtacatcatc ttctcgccgc tcattataac
     2941 gatctataat cgcctggaag cggcgggtga agttaatccc ttgcaactgg ttcactttct
     3001 tgaagtcgct gatcgctttt tccagtaatt tttgtaataa ctggatcttc gttgccggaa
     3061 gtttgatctt gttaattcgc gccagataat cttcgtcaaa aatatcgatg gattccgctt
     3121 ttttatcgcc aagaaaataa atttcttcta cgccatcagc ttttaacgct tctgcaatca
     3181 tttcacgaac gcgtgcattc atctgggtaa catccggtgc gtcacctttc gtcagtttga
     3241 aaacaattga acgaacagca agataatagt gaatatagtc acgttctgtc tgtgataatg
     3301 cttcgctgcc gcagcagacg tcgtaggcgg ctttcatgcg tttaaccagt cccataaaac
     3361 gacgttcaac tttctgggta cgcagaacaa attccgccgc gcggttgagg caggataatt
     3421 gcgcttgtgg ctcaccacta aaataatccc gactgtcaaa ttcgtaaaag acttgcccca
     3481 acaaatcgag atggttttta acttctatta ccgattgctg aatatcttca aagttggtgg
     3541 catcaatgcg ggaatacatt gccagtgcct ggttcatctg acttttaatg ccgatgtagt
     3601 ccaccactaa ccctttactt ttgccttcca gtttacggtt aacgcgagaa atagtctgga
     3661 taagattatg tttttgtaag ggtttatcaa tatagatggt atccagttcc gggacgtcga
     3721 aaccggtcag ccacatatca acaacaatgg caattttgaa attcgattta gcgtttttga
     3781 actgcttatc cagctctttg cgatattctt ttgtgcccag taaatcataa agcgcctcgt
     3841 cgtcatcttt accgcgcgtc atgaccatct tcaccatttc tgaaggcggt aactctttct
     3901 gctcctgttc cgtcaggacg acgccatcgg gtgcttgctt cacttcaaac caggcagggc
     3961 gaatagcttt aagctgacgg tagaaatccc aggcaatttc acggctggca caaacaaaca
     4021 tggctttgcc ttttacggtg gaaccttcgg ctacgcgttt ttcataatgt ttggcaaaat
     4081 cttctgcgag ggcttttaac cgatcttcat cacccagaac cgcattcatg gtggcggtgg
     4141 cttttttgct ttcgtcgatt tgccactcat tggtgcctgc gtttgcgcac tcttcgtaat
     4201 acttttcgac ttcttccagt ttgctggagt ccaggatcac tttagccgca cggccttcgt
     4261 acacgatgcg tacagtgatt tcatcctgaa cggattcggt catggtgtaa ctgtcgatca
     4321 cctcaccgaa gacatcgagc gtcgcgtcaa tcggtgtgcc ggtaaagcca acataggtgg
     4381 cgtttggcag tgaatcgtgc aggtatttcg caaagccata cgttttgcgc acttttccgc
     4441 tttctttatc aacgatgact ttctggtcga ggttaacctg gctacgatgt gcttcgtccg
     4501 agatgcaaat gatattgttg cgttcagaaa ggagttcggt gtcttcggtg aatttatgga
     4561 tcgttgtcag aaagactccg ccactattgc gtcctgccag ttgattacgc aaatcttcac
     4621 ggctggtaac gggaacgatg gtgtcgtcgc caatgtaatt tttggcgttg cacatttgcg
     4681 cagaaagctg atcgtccaga tcggtgcggt cggtgatcaa aacaatggtc gggctggcaa
     4741 actccacgct cttcatcaaa agacgcgtta aaaattgcat ggtgtaactt ttaccacagc
     4801 ccgttgcgcc aaagtaagtg ccgcctttac cgctaccgaa aggtttacgc gcttgcttga
     4861 tgctgtaata gagtttgcgg gcggcatagt actgcggata tcggcagcaa atttttactt
     4921 cgtgcttggc tttatccggg aagcagataa agtttttaat cacatccagc agacgtaccg
     4981 gatgaaacag cccctgaatc attgagtgca atgatggaat tccgtcctgt tcacggtttt
     5041 cattaccggt gactttgcgc catgagtaaa agtattcata gggcgcaaac aggttgccca
     5101 tccggttatt tacgccatcg ctaataatgc agagcgcgtt gtagataaac agttgcggaa
     5161 tatcccggcg atagcgttta cagagctgct tccaggcatc gccaatactg gcttcctgct
     5221 cgcgcaccgc acttttaaat tcaaagacga ccaatggcag accattgata tagagaatgc
     5281 cgtcaggaat acgagtctga ttatctttgc cggagatttt aagctggtta acaatcttaa
     5341 tccggttaag cggcggattc atataggaag gcgggagttc cgccgcctgt tgcaacggga
     5401 catcttcggc gtcaaatatc tggcgcagtg cggcaggtag atgccgggtg tcgagcaatt
     5461 caatatagag atctttttgt tgccgatcgt cgcgtttgaa cagaaaacca tttgccagcc
     5521 agcgacaaaa tgttttgttg ctttcataaa gatcggaggc cggaagcgtg gtgaactgtt
     5581 tgatcagtcg ctgaatctct tcttcagtaa tgccatcagg ctggtagcgt gccgctaaat
     5641 aatgacggag atcgtcttcg ataatgacct gatcgaggct cgaacgtggg acattatcgc
     5701 cgatcaggtg ttgatatccc tgatcctgta acagttcaat gatcgcttgt tctaattttg
     5761 cttcactgaa agagagactc atatcgcgct ccaaccctgg ctaatttctg gtaagcattc
     5821 ccgtatcagt agaaaacctt accagaaagc ccctgatttt acaggggcaa aatgcgttat
     5881 gcggcttctg tatcggtggt gagatccgga agatcttcca gggatagctc gccggagatg
     5941 agtttcggga gcaaggtgcc tcggaggttg gtgagatatt ctttttga
//
LOCUS       DAFGPF010000200         5956 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFGPF010000200 DAFGPF010000000
VERSION     DAFGPF010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5956
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.201"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            225..806
                     /gene="mdaB"
                     /locus_tag="LSX49_004947"
     CDS             225..806
                     /gene="mdaB"
                     /locus_tag="LSX49_004947"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HBL7171215.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            837..1151
                     /locus_tag="LSX49_004948"
     CDS             837..1151
                     /locus_tag="LSX49_004948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBL7171216.1"
                     /translation="MITVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAVKGDVLEMNIRILQP
                     GL"
     gene            complement(1196..2083)
                     /locus_tag="LSX49_004949"
     CDS             complement(1196..2083)
                     /locus_tag="LSX49_004949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL7171217.1"
                     /translation="MIQKDKVRVDIFGERFRTRASQLTPGLRVVASYINEHREVVLEQ
                     TAMEIAATLNTSDATVIRAIQALGFAGLRDLKRTLEQWLGPALSSSEKMSTTVSNLTS
                     DVNTAIDFVLEGHLYTCNVLSEPENRHALAQAVALLVQARQVAIFGIGASGILADYTA
                     RLFNRIGLPATALNRTGIGLAEQLIALQRGDVLIMMAQKSAHREGLTTLREARRLGIP
                     VILLTNALDSRFSKDASIVIHVPRGDEKGKTPLHGTVLLCLEMIVWSVASAVPQRAVK
                     TIKRINDFHRGLKTGRKNG"
     gene            complement(2080..3027)
                     /locus_tag="LSX49_004950"
     CDS             complement(2080..3027)
                     /locus_tag="LSX49_004950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL7171218.1"
                     /translation="MRLFFSLLILLSFFSRATEPVQVFTDDLGRKVTVPAHPKRIVSL
                     HDLDITIPLIELGVPPVASHGRTRPDGSHFIRSGALLTGVDFDNSSIAFIGTADIDIE
                     AIVAAKPDLIITEPTRNTPIEQLEKIAPTVSIDHLKGGAPEIYRKLAELTGTQSQLAI
                     LERRYQAQINALKATLDSQKITVSVIQANQGKINVMHSYHSLGRVLRDAGFRFPPLIE
                     SIPEGGRMDVSAERLPELDADFVFATWRGDTGGKPQDELAAMEKVMPGWCQFLTACRS
                     GRYVLISREEAISNSFASLGLMAAQIQSQIAGRPLPEAK"
     gene            complement(3038..4075)
                     /locus_tag="LSX49_004951"
     CDS             complement(3038..4075)
                     /locus_tag="LSX49_004951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311941.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL7171219.1"
                     /translation="MNVGLRPLRVGKFSTLVRPKNLLLLGGLFLLAVGILIFGLMQGS
                     FSVPASEVGRALFAPENVSTDARYIVQDIRLPRVIMALLCGAMLGMAGAAMQSIARNG
                     LADPGLIGVKEGCSVAVLWLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCARDISRPR
                     FVLIGIGVSWFFAAGIGVFMTTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAA
                     LLLLFTARTADIALLGHQVATGLGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLI
                     APHISRFILRGGQTTLLLGSAVSGALLVILADSIGRLAFLPLQLPAGIIISLIGGPFF
                     LLLLWQRRNSF"
     gene            complement(4084..5067)
                     /locus_tag="LSX49_004952"
     CDS             complement(4084..5067)
                     /locus_tag="LSX49_004952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL7171220.1"
                     /translation="MMRTGLVTVIFLALLLVGCVVYPGIGARFIAPQTVLQAFLHFDP
                     QNFDHNVIVRLRLPRLAAALLTGASLGVAGALLQAVIRNPLGEPHILGLNAGAALAVV
                     AASALGLAFPVGRPLLASTGGALLFLLILLLSSAGRSGLTPMKVTLCGVALSAFVSSI
                     TAAILILDEQTLLAMRTWLAGDLAGQDWATLGTSAWFSLGGFVLALYLAPSLNMLALG
                     DRMAQGLGVSVLRTRTFTLLAIALLCGAAVSIAGPIGFVGLLVPQIVRRLVSADLRVL
                     LPLSACVGALLLLLADIIARTLFTPHELATGVMTALVGAPVFVIMATRMFK"
     gene            complement(5064..5873)
                     /locus_tag="LSX49_004953"
     CDS             complement(5064..5873)
                     /locus_tag="LSX49_004953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL7171221.1"
                     /translation="MAHNAKGQGLILDNVSAGYHKKIIVDGVSFSVPTEKMTVLVGAN
                     GCGKSTLLSTIARILQPMGGSILLDGKAIHEQPTKALSRRLGILPQSPLLPEGLTVYE
                     LVSRGRFPWQNFIRQWSDADEQAVEEALKLTGTQEFAHLPVEKLSGGQRQRCWIAMVL
                     AQKTPYILLDEPTTWLDLRYQVEILELLHDLTRHHGRTVVVVLHDLNFAVNYGDTLIF
                     LRQGKVVRVLNEGEHCTPELVKAVFDVDVHASINPLTGKPFFMPFRGVEKV"
BASE COUNT         1681 a         1610 c         1379 g         1286 t
ORIGIN      
        1 gaaaaactcc tgtatcattt gcataataca tctctcctgt gggagcttat gggaagttga
       61 tttaagtatt gtcattttca gaaaatattt atcccgcatc ggtgaatcag agaaagatca
      121 gacttttgct aaattcgcaa aagactttgc acattttgct aatttcaccg taccgctctg
      181 tgacgtacta tagtcggcaa acgtctcacc ttgaggttaa aaaaatgagc aacatcctga
      241 ttatcaacgg cgcgaaaaaa ttcgcccact ccaatggtca actgaacgac accctgaccg
      301 aagtcgcgga tggcacactg cgcgacctcg ggcatgatgt ccgcattgtt cgcgccgaca
      361 gcgactacga tgtcaaagcg gaagtacaaa actttctctg ggctgatgtg gtgatctggc
      421 agatgcctgg ctggtggatg ggcgcgccgt ggacagtgaa aaaatatatt gatgatgtat
      481 tcaccgaagg tcacgggact ctgtatgcca gcgatggtcg tacccgcaaa gatccatcaa
      541 aaaaatacgg ttccggcggc ctggtacagg gcaaaaaata tatgctttct ctgacctgga
      601 acgcaccaat ggaagccttc accgaaaaag atcagttctt ccacggcgtt ggtgttgacg
      661 gtgtgtacct gccgttccat aaagcaaacc aattccttgg catggaaccg ctgccgacat
      721 ttatcgctaa tgacgtgata aaaatgcctg atgttccccg ctatactgaa gaatatcgca
      781 agcatcttgt ggaaattttt ggttaactag agctctggct ttagaaggag ttaaccatga
      841 ttacagtaat cgcagaaatt cgtactcgtc ctggtcaaca tcaccgtcag gcagtgttgg
      901 atcagtttgc taaaatcgtt ccaaccgtac tgaaagaaga aggttgccac ggctatgcgc
      961 caatggtgga ttgcgctgct ggcgtgagtt tccagtctat ggcaccggat tctatcgtga
     1021 tgattgagca gtgggaaagc atcgcgcatc ttgaagcgca tctgcaaacc ccgcacatga
     1081 aagcatatag cgaagccgta aaaggtgacg tgctggagat gaatattcgt atcctgcagc
     1141 cggggctttg acatttctaa aaagaggccg gtgctgctac cggtctcagc ccagattagc
     1201 cattctttct tcccgttttc agtcctcgat ggaaatcgtt aattcgctta atggttttaa
     1261 ccgcacgctg cggcactgcg gaagctaccg accagacaat catttccaga cacaacaata
     1321 ccgtaccatg tagcggcgtt ttcccttttt catccccgcg cggaacatga atcacgatac
     1381 tggcgtcttt gctaaaacgt gaatccagcg cgtttgtcag caaaataaca gggatcccca
     1441 gccgcctcgc ctcacgaagc gttgtcagcc cttcccggtg cgcagatttt tgcgccatca
     1501 tgatcagaac atcgccacgt tgaagcgcga tcagttgctc ggcaaggcca atacccgtac
     1561 ggtttagtgc cgtggcaggc aaacctatgc ggttgaatag tcgtgcggta tagtccgcca
     1621 gaatacccga agcgccaatg ccaaaaattg cgacttgccg tgcctgcacc aacaacgcta
     1681 cagcttgcgc aagcgcgtgg cggttttcag gctctgacag gacattacag gtatacaaat
     1741 gcccttcaag aacaaagtcg attgcggtgt taacatcgct cgtcaagtta ctcaccgtcg
     1801 tagacatctt ttcgctggaa ctaagggctg gaccaagcca ctgttccaga gtgcgtttca
     1861 gatcacgcag cccggcaaac cccagggcct gtatagccct gataactgtg gcatcggaag
     1921 tgttcaacgt ggccgcaatt tccatcgccg tttgctcgag taccacttca cgatgctcat
     1981 taatgtagct ggcgacaact cttaacccag gcgttaactg actcgcgcga gtgcgaaaac
     2041 gctcaccaaa aatatcaacc cgcactttat ctttctggat catttagcct ccggtagagg
     2101 tcgccctgca atttgtgatt gtatctgcgc agccatcagc cccagagatg caaaggagtt
     2161 agaaattgcc tcttcacgag aaatcagcac ataacgcccg gaacgacagg cagtcagaaa
     2221 ctgacaccat cccggcatga ctttttccat tgctgccagc tcatcctgag gtttaccacc
     2281 ggtgtcaccg cgccaggttg caaaaacaaa atcggcatcc agttcaggta aacgctccgc
     2341 gctcacatcc attcgcccac cttcaggaat gctctcaatc agcggcggaa aacgaaaacc
     2401 agcatcgcgt aatacccgtc ccagcgaatg atagctatgc atcacattaa tttttccctg
     2461 gtttgcctga atcaccgata ccgttatttt ttggctgtcc agcgtcgcct tcagcgcatt
     2521 gatttgtgcc tgatagcggc gttcaagtat cgccagctgc gactgcgttc ctgtaagttc
     2581 tgccagcttg cgatagattt ctggcgcgcc ccctttgaga tgatcaatgc tcaccgtggg
     2641 cgcaattttt tcaagttgtt caatgggcgt attacgggtc ggttctgtga tgatcaagtc
     2701 aggctttgcc gccacaatcg cttcaatatc aatatcagcg gtaccaataa aggcgatcga
     2761 tgaattatca aagtcgacac ctgtcaataa cgcgccagat cgaatgaaat ggctaccgtc
     2821 aggccgagtt cgcccgtggc tggcgacagg aggtacaccg agctcaatca gaggaatagt
     2881 gatatcaaga tcgtgtaaag agacaattct ctttggatga gcaggaacag tgactttgcg
     2941 ccctaaatca tcagtaaata cctgaacagg ttctgttgca cgggaaaaaa atgacaacag
     3001 tatcagcaga gaaaaaaata aacgcatata actcccgtta aaaactgttc ctgcgctgcc
     3061 agagcagtag taaaaaaaat ggtccaccaa tcagtgagat aatgattccg gcaggcagtt
     3121 gcaaaggcaa aaaagccaaa cgaccaatgc tatccgccag aataactaac aacgcccccg
     3181 ataccgcgct ccccagcagt aatgtcgtct gcccgccacg tagaataaaa cgtgatatat
     3241 ggggtgctat caatccgaca aaaccgatgt taccaacaca cgaaacgcag acggctgtca
     3301 ggattatggg tgcggcgaca cgtaacaacg ccagacgaga actattcacc cctaacccgg
     3361 ttgcaacctg atgaccaagc agagcgatat ccgcagtcct ggcggtgaac agcaataaaa
     3421 gagcggctgg caacatccaa caggctgaaa taccgactaa catccagtta gctgcatgca
     3481 ggcttcccga taaccacatc aatgcagttt gtacatctcg aacatctgca gtggtcataa
     3541 atacaccgat accggcggcg aaaaaccagg aaacaccaat accaatcaga acaaatcgcg
     3601 ggcgggaaat atcgcgcgca caaaaaatca cgattaaagc caccaacagg ccaccagcaa
     3661 gaccagccac tggacgccag aacattccca gcattggaaa ctggaaaatc agccacagca
     3721 cagccacgct acatccttct ttgacgccga ttaaaccagg atcggcaagg ccgttacgtg
     3781 caatggattg cattgcggcc cctgccatac ctaacatggc cccgcatagc aatgccatga
     3841 tgactctcgg caagcgaata tcctgcacaa tataacgtgc gtctgtgctt acgttttctg
     3901 gagcaaacaa cgctcgtcct acttccgatg ccggaacaga gaaagaaccc tgcatcagac
     3961 cgaatatcag tattccaacc gcaagcagga acagcccacc aagcaacagc agatttttag
     4021 ggcgcaccag tgtcgaaaac ttaccaacac gtagtgggcg tagcccgacg ttcattatcc
     4081 gactcatttg aacatcctcg tcgccataat gacaaaaaca ggcgcaccaa ctaacgccgt
     4141 catgacaccg gtcgctaact catggggcgt gaaaagcgtc cgggcaataa tatctgccag
     4201 taataacaaa agcgcgccga cacaagctga aagagggagc agaacgcgca gatccgctga
     4261 taccagacgc cggacaatct gcggtactag caggccgaca aaaccaatgg ggccagcaat
     4321 cgatacggct gcgccacaga gcaacgcgat cgcaagcagg gtgaatgttc gcgtgcggag
     4381 tacagagacg cccagcccct gcgccatgcg atcgcccagt gccaacatgt taagggaggg
     4441 tgcaaggtaa agggctaaca caaatccccc cagagaaaac caggcggacg tacccagcgt
     4501 cgcccaatcc tgccccgcta aatcacctgc tagccatgtc cgcatcgcca gcagtgtttg
     4561 ttcgtcaaga atcaggattg cagccgttat tgaggacacg aacgccgata gcgccacgcc
     4621 gcataaagta actttcattg gcgttaaccc tgaacgccct gcggaggaaa gcagcaatat
     4681 caacaggaac aataacgcgc cccccgtaga tgccagcagt gggcgtccaa ccggaaaggc
     4741 cagtccaagc gcactggcgg caacgacagc aagagcggct ccggcattta agcctaaaat
     4801 atgtggttcc cccaatgggt tacgaatgac agcctgcaac aaagcaccag caacaccaag
     4861 agaagcaccg gtaagcaatg ctgccgctaa acgcggcaaa cggagtctta caattacgtt
     4921 gtgatcgaag ttttgcggat caaaatgaag aaatgcctgc aacaccgttt gtggtgcaat
     4981 aaatcgggca ccaatccctg gatataccac gcatcccacc agcagtaagg cgaggaaaat
     5041 tacagtaacc agccctgtgc gcatcatact ttttctacac cacgaaacgg catgaagaac
     5101 ggctttcccg tcagaggatt tattgatgcg tgaacatcaa cgtcaaagac agcttttacc
     5161 agttcaggcg tgcaatgctc cccctcattc aacacacgca ccactttccc ctggcgtaaa
     5221 aatatcaacg tatcgccata attgacggca aaattcagat catgcaacac cacgacgact
     5281 gtacgcccgt gatgacgcgt taaatcatgt aataactcaa gaatttcaac ctgataacgt
     5341 aaatcaagcc aggttgtggg ttcatccagc aggatataag gcgtcttttg cgccaacacc
     5401 atcgcaatcc agcaacgctg gcgctgccca ccagagagtt tttcaacagg taaatgtgca
     5461 aactcctgcg taccggttaa tttcagggcc tcttccaccg cctgctcatc ggcgtcgctc
     5521 cattgacgta tgaaattttg ccagggaaaa cgcccacgcg acaccagttc ataaacggtt
     5581 aagccctccg gcaataatgg cgactgcggc aagatcccaa gtctacggga taacgctttc
     5641 gttggttgct cgtgaatcgc tttgccatca agcaatatcg aaccgcccat aggttgcaag
     5701 atacgtgcaa tggtgctgag caacgtcgac tttccacagc cgtttgcccc aaccagaacg
     5761 gtcatttttt ctgtgggaac ggagaaagaa acaccatcaa caatgatttt cttgtgatac
     5821 ccggcagaaa cattgtcgag gatcagcccc tgcccttttg cgttatgtgc cacgtgtacg
     5881 ccaacttaat caaagacaaa caaaaataaa actcattctc ctttgagagt ttgacgccac
     5941 aaaatgtagt agtcaa
//
LOCUS       DAFGPF010000201         5746 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFGPF010000201 DAFGPF010000000
VERSION     DAFGPF010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5746
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.202"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1415
                     /gene="norV"
                     /locus_tag="LSX49_004954"
     CDS             <1..1415
                     /gene="norV"
                     /locus_tag="LSX49_004954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HBL7171222.1"
                     /translation="HWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDH
                     KFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSIN
                     GHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFG
                     QHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSH
                     GVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAV
                     KIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAF
                     GSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREIARQWALAPL
                     PQSTVNTVVKEETSAATTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNF
                     LCPECSLGKDVFDELASEAK"
     gene            1412..2545
                     /gene="norW"
                     /locus_tag="LSX49_004955"
     CDS             1412..2545
                     /gene="norW"
                     /locus_tag="LSX49_004955"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HBL7171223.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDACIPLTLIAADSMDEYNKP
                     DLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILA
                     TLDRQRCIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGEPQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLSM"
     gene            complement(2767..5019)
                     /gene="hypF"
                     /locus_tag="LSX49_004956"
     CDS             complement(2767..5019)
                     /gene="hypF"
                     /locus_tag="LSX49_004956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HBL7171224.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLLEEPETFLVQLHQHCPPLARIDSVEREPFIWSQLPTEFTIRQSTGGAMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ACDKEYCDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGNIVAI
                     KGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISN
                     EQALADLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVP
                     PVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDAHPGYVSSQWAREMNLPTQTVLHHHAHAAACLAEHHWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALAGGDLAAKQPWRNLLTQCLRFVPEWQSYPE
                     TVSVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
                     LATSCHGVTHPVTMPLVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGGAALMRE
                     QATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RWLAGEVQNG"
     gene            complement(5172..5699)
                     /gene="hydN"
                     /locus_tag="LSX49_004957"
     CDS             complement(5172..5699)
                     /gene="hydN"
                     /locus_tag="LSX49_004957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HBL7171225.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
BASE COUNT         1379 a         1640 c         1528 g         1199 t
ORIGIN      
        1 ttcattgggt tggtcaacgt gactgggaag tgcgtgattt tcacggtaca gaatataaaa
       61 cgctgcgcgg cagcagctac aacagctacc tcatccgcga agaaaaaaac gtgctgatcg
      121 acaccgtcga ccataaattc agccgcgaat ttgtgcagaa cctgcgtaat gaaatcgatc
      181 tggcggatat cgattacatc gtgattaatc atgcagaaga agaccacgcc ggagcgctga
      241 ccgaactgat ggcgcaaatt cccgatacgc cgatctactg tacagccaac gctatcgact
      301 cgataaatgg tcatcaccat catccggagt ggaattttaa tgtagtgaaa actggcgaca
      361 cactggatat cggcaacggc aaacaactca tttttgtcga aacgccaatg ctgcactggc
      421 cggacagcat gatgacttac ctgacaggcg acgcggtgct gttcagtaac gatgctttcg
      481 gtcagcacta ctgcgacgag catctgttca acgatgaagt ggatcagact gagcttttcg
      541 agcagtgcca gcgttactac gccaatatcc tgacgccgtt cagccgcctg gtaacgccga
      601 aaattaccga gatcctgggc tttaacttgc cagtcgatat gatagcgacc tctcacggcg
      661 tggtatggcg cgataacccg acgcaaattg tcgagctgta cctgaaatgg gcggcggatt
      721 atcaggaaga cagaatcacc attttctacg acaccatgtc gaataacacc cgcatgatgg
      781 ctgacgctat cgcccagggg attgcggaaa ccgacccacg cgtggcggtg aaaattttca
      841 acgtcgcccg aagcgataaa aacgaaatcc tgaccaatgt cttccgctca aaaggcgtac
      901 tggtcggcac ttctacgatg aataatgtga tgatgccgaa aatcgccggg ctggtggagg
      961 agatgaccgg attacgcttc cgtaacaaac gcgccagcgc tttcggctct cacggctgga
     1021 gtggcggtgc ggtggatcgt ctttccacgc gcctgcagga tgcgggtttc gaaatgtcgc
     1081 ttagcctgaa agccaaatgg cgaccagacc aggacgctct ggagttatgt cgtgaacacg
     1141 gtcgcgaaat cgcccgtcag tgggcgctcg cgccgctgcc acagagcacg gtgaatacgg
     1201 tggttaaaga agaaacctct gccgccacga cggctgacct cggcccacgg atgcaatgca
     1261 gcgtctgcca gtggatttac gatccggcaa aaggcgagcc aatgcaggac gttgcgccag
     1321 gaacgccgtg gagtgaagtc ccggataact tcctgtgccc ggaatgctct ctcggcaaag
     1381 atgtctttga cgaactggca tcggaggcaa aatgagcaac ggcattgtga tcattggttc
     1441 gggcttcgcc gcccgccaac tggtgaaaaa tattcgcaaa caggacgcct gtattccatt
     1501 aaccctgatt gccgccgaca gcatggatga gtacaacaaa cctgacctca gccatgttat
     1561 cagtcagggg caacgtgccg acgaccttac ccgccagacg gcaggtgaat ttgccgagca
     1621 gtttaatctg cgcctgtttc cgcacacctg ggtaacggat atcgatgccg aagcccatgt
     1681 ggtgaaaagt cagaataatc agtggcaata cgacaagtta gtgctggcaa ccggtgccag
     1741 cgcctttgtc ccgccagtgc ccgggcgtga gttaatgctg acgttaaata gtcagcaaga
     1801 gtatcgcgcc tgtgaaacac aactgcggga tgcccgacgc gtgttgattg ttggcggtgg
     1861 tttgattggt agcgaactgg cgatggattt ttgtcgggca ggcaaagcgg tcacgctaat
     1921 cgacaacgct gccagtattc tggcgtcgtt aatgccaccg gaagtcagca gccgcttgca
     1981 gcatcggttg acggagatgg gcgttcatct gctgttaaaa tctcagttgc aaggactgga
     2041 aaaaacagat tctggcattc tggcaacgct ggaccgccag cgctgcatcg aagtggatgc
     2101 ggtaattgcc gccaccggac tgcgcccgga aaccgccctg gcacgacgcg ccgggctgac
     2161 gattaatcgc ggcgtttgcg tcgatagtta tctgcaaacc agtaatgccg atatttatgc
     2221 gctgggcgat tgcgcggaaa ttaacggtca ggtattgccg ttcctccagc cgattcaact
     2281 tagcgcgatg gtgctggcaa aaaatcttct cggcaataac acgccgctga aactcccggc
     2341 gatgctggtg aaaatcaaaa cgccggaatt accgctgcat ctggcaggcg aaccccagcg
     2401 tcaggattta cgctggcaaa ttaataccga acgccaggga atggtggcgc gcggtgttga
     2461 cgatgctgac cagcttcgcg cctttgtggt cagtgaggat cggatgaaag aggcatttgg
     2521 attgttgaaa acgttgtcga tgtaggcgag ctacagtgcc ccaaatgtcg gatgcggcgc
     2581 tgacgcgtct tatccgacct acagggaacg catgtgttga tcacataata cgtttatgtc
     2641 gcattgcact gtcccaaaat gtcggatgcg acgctagcgc gtcttatccg acctgcgggg
     2701 atgaatatgt aggccggata aggcgttcac gccgcatccg gcaatggtgt ccaaatgcaa
     2761 cacgctttat ccgttctgga cttcacccgc taaccaacgc gccgcagcaa taaccccctg
     2821 ccccagagac aacccgccat cgcccgcagg taaactctgt ggaaagagca atgtgaaatc
     2881 agcgagataa tgcgccagac gtgcacgcag caaacggtta tgaataaccc cgccgctaaa
     2941 taccagcgta gtgataccac gcatcgtggc ctgctcacgc atcaacgcgg cccccccctg
     3001 cgccagcgca tcatgaaacg cccacgcacg ttgattaacc ggagcctgcc agttcagcca
     3061 ctgctgccag aaggtggcga gatccagttg attatccacc agcggcatcg tcaccggatg
     3121 cgtcacgccg tggcacgaag tcgccagcgc ctccagagca caagccgctt caccttcata
     3181 acttaacgtg gctggcgcac agcccagcgc cgccgctacg gcatcgaaca accgcccaca
     3241 cgatgacgcc agtggtgcat tgattccacg ctcaatggcc cgcgccagca cgctccagtt
     3301 ttgctgttgc acacttaccg tttcgggata actctgccac tccggcacaa aacgcaagca
     3361 ctgcgtcagc aggtttcgcc acggctgctt tgcggcaaga tcgccaccag caagcgccac
     3421 tgcaggcaag ccgcccaggt gctcgcattc acgatagttc acccgcaggc actctccccc
     3481 ccacaaagcg ccgttctccc ccataccaat accgtcgagt gtcaacgcaa tgacatctcc
     3541 gccatccagc ggccagtgat gttctgccag acatgccgct gcgtgagcat gatgatgcag
     3601 caccgtttgc gtcggcagat tcatttcgcg cgcccactgg ctggagacat agcccggatg
     3661 cgcgtcatgc acaacgtatt gcggagtgaa atcgtagatg ttttgcatca ggcgtaacgc
     3721 ttcgcgccac tgcatctgga tgccatcgtc acttaaatcg cccagatgct gactcaacac
     3781 cgcttgttcg ccgcgcacca ggcagaaggt atttttcaga tccgcgccga gacacagcac
     3841 aggcggaaca tttttaaagc ccggaggcaa agccagcgca tccggcacat acccccgcga
     3901 acggcgcagc atttcgccgc tttcgcgcac caccgaatca tccatccgct gcacgatgtc
     3961 gcggttatgt atcaagaatc cgtcggcaat gccctgcaaa tccgccagcg cctgttcgtt
     4021 gctgatagcc ggtggtttac cgctcaggtt gccggaggtc atcaccagcg ggcattgcag
     4081 ttcctgtaac agcaaatgct ggagcgggtt cgcaggcaac attaccccga cttcgttaag
     4141 gccaggggcg atatcatcac aaagctcagg tacatatttt ttatccacca gcacaatcgg
     4201 cgcggcgggc gtggtaagca actggcgcgc agcgtctggt aaaccgtcag ccactggcaa
     4261 catgaccgcc agcggtttcg ccgggcgatg tttgcgcgcc cgaagtgtcg ccaccgcgtt
     4321 actgttacgt gcatcgcagg caagatgaaa tccgccaatc cctttgatgg cgacaatgtt
     4381 gcccattttt aactgtgcga tagctgcctg taatgccgcc tcttgttctg catgttcacc
     4441 atgacttacc cattcaagat gggggccaca ctccgggcag gccaccggct gggcgtggaa
     4501 gcgacgatcg agcgggtcac agtactcttt gtcacaagcc ggacacagcg gaaacgccgc
     4561 catcacggta aacgggcggt cgtaaggcat ggcgcgaata atggtgaaac gcgggccaca
     4621 gtgggtacag ttgataaacg gataacgata acgccgctcg cccggggtat tcatttcggc
     4681 aaggcaagca gggcaagtcg cggcatcggg aactatttgc gtattcatag cgccgcctgt
     4741 gctctggcgg atagtgaact cggtgggcag ttgtgaccag ataaacggct cacgctcgac
     4801 gctatcaata cgcgccagcg gcggacaatg ctgatgcaat tgaacaagaa aggtttccgg
     4861 ctcttccagc agccggactt ctacgccatc gccgtcatta cagacatcgc cgtgaagatt
     4921 taattgctgt gccagttgcc agacaaacgg acgaaaaccg acgccctgca ctttgccacg
     4981 aatacgcagt tggacaccgc aagatgtgtt ttttgccatt gagttattcc cgccatcatg
     5041 aattgcgtaa cccgcccagc cggacacgac agcgtcgcat ccggcagtca caggtcggcg
     5101 atactgcccg cttcgtattc tacgaatatt tccgggaatt cctttgatac cagaacagtt
     5161 ctgtaagatt tttagaacat cagcgccgtg cggcggcgtt tttctgcgct cagttgttca
     5221 agtttattac gatcgacaca aatcagcgca tgggtcgggc aagccgccat acacgccggg
     5281 ccgtcttcac gatggttgca caggtcgcat ttattggctt cggctttgtc agcccgtaca
     5341 ttcagccctg cgccgctgtt gcgaatcacc ggacgcacca ccacttccat cgcaccatat
     5401 gggcaagcca caacgcaggt tttgcaacca atacaacgtt cctgcatgac atgaacaaac
     5461 cctttatcac ggctgatagc accattcggg cagacgttag cgcacggtgc atcttcacac
     5521 tgacggcaga ctgtcgccgt ggaaatgttc acacctttaa tgacatggat tcgcggtaaa
     5581 aatgtttccg gggtcagcga tgcacagtcc tgattttcct gatgagaaac cacgcacgcc
     5641 acttcacagg tacggcaacc aatacattta ctcgcgtcag caatgatgaa acggttcatc
     5701 aaattctcca gcaataacag ttaatgcgcc gatacattca caaatc
//
LOCUS       DAFGPF010000202         5712 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFGPF010000202 DAFGPF010000000
VERSION     DAFGPF010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5712
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.203"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1148..1864
                     /gene="nanC"
                     /locus_tag="LSX49_004958"
     CDS             1148..1864
                     /gene="nanC"
                     /locus_tag="LSX49_004958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HBL7171226.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
     gene            1884..2990
                     /gene="nanM"
                     /locus_tag="LSX49_004959"
     CDS             1884..2990
                     /gene="nanM"
                     /locus_tag="LSX49_004959"
                     /EC_number="5.1.3.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HBL7171227.1"
                     /translation="MNKTITALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGDLYVFGGIGKNSKGLTQ
                     VFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGDNLKWNRLAPVSSPDGVAGGFAGISNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGESAGGKAVTDSVLISVKDNKVTVQN"
     gene            3054..4034
                     /locus_tag="LSX49_004960"
     CDS             3054..4034
                     /locus_tag="LSX49_004960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HBL7171228.1"
                     /translation="MNAIISPNYYYVLTVAGQSNAMAYGEGLPLPDREDAPHPRIKQL
                     ARFTHTHPGGPPCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGILIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPHNKFLGVCWMQGEFDLMTSDYASHPQHFNHMVEAFRRDLKQFHSQLNNIT
                     AAPWFCGDTTWYWKENFPHAYEAIYGNYQNNVLANIIFVDFQQQGERGLTNAPDEDPD
                     DLSTGYFGSAYRSAENWTTSLRSSHFSAAARRGIISDRFVEAILQFWRER"
     gene            complement(4617..>5712)
                     /locus_tag="LSX49_004961"
     CDS             complement(4617..>5712)
                     /locus_tag="LSX49_004961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA helicase"
                     /protein_id="HBL7171229.1"
                     /translation="GYCNSLCYHGKLQPKRGMEKGTIFPAMGYLHIDGRGMKPNGGSR
                     YNPLEAETIAAWLVAHKDDIERHYGEPLYKVVGVVTPFSAQVNAIKTSLRKLEINGKD
                     EQGSLTVGTVHSLQGAERAIVLFSPVYSKHEDGRFLDSNSSILNVAVSRAKDSFLVFG
                     DMDLIEMQPAFSPRGLLAKYLFSSDNNALQFEFQKRQDLISAHTQISTLHGVEQHDGF
                     LNKTLAGAQKKITIISPWLSWQKVEQTGFLASMALARSRGIDITVVTDKNCNIAHVDD
                     DKRQEKQHLLNDAVEKLNKMGIATKLVNRVHSKIVIEDEELLCVGSFNWFSAAREDKY
                     QRYDTSLVYRGEGVKNEIKAIYGSLDQRQL"
BASE COUNT         1686 a         1255 c         1215 g         1556 t
ORIGIN      
        1 gtaaaatcaa cataaaaaat tcagcaaaat ttaatattcg ttcaactagc cgtctcacat
       61 atgacattat tagtcaactc catttaccac aaaatggcta tttcatggaa cgcagtaatt
      121 tcttagtggc tattatcaag ctaattctta ggtccctagc gattattcct ggctggttcg
      181 tcagtttagg tcatgagatt gttacattcc tttttatcct ggagatatgg gggaacgcag
      241 gcgacgcttt ttcatctaca tccgttggta aatatggctt tggtcactac gacttaaacc
      301 ctcctcaatc acagctactc gccgggcgat atggcaaaca aactaattga aacatcatcc
      361 tgaaaacacc agcatcaaca agcctctcca gatcgacatc aggagtgacc agttacaagc
      421 cacaaaccaa gaaacatatt tcatgatgag aattatgctc agcctgatgg cgggtaaaca
      481 cttattttca ccaagctcac tgagttagct tgcaaagctt tctttgttta tattctaaat
      541 aaattattta taaaacatat agttaaaaga aaatctttag tttttgaaga ccaccgcaag
      601 tgttcgtctg gcttcacatg gcatctgcct cttagaaaaa gatcgacata ttttgtgaca
      661 cgaattgcaa atctggtttt gttgtatgga ttgcgtgatt tttgatctgg tataacaggt
      721 ataaaggtgc accacgatag tcaatgaaac tgggcatctc gcaatctatg gcaaacatca
      781 cttcagttct ttctcatcgg gtgatgaaaa cgcacttcag tctgaaagga atatgaaaat
      841 gagatcaaca gacactctat tttatgactc tgggtaaaat ggattgagta agcgatatag
      901 cttacgaaaa ttcaaatcaa ttaaacatca gcagagattt tatactcagg tatttaatct
      961 ggctctctgt ttatttaaat aatgtggaaa gagatttttc acaggagaca ttatacaaaa
     1021 aatataaaat acagctaccc gttgccaaag acactataag cctggcaaaa aatattacac
     1081 aacataaatg ctaattgttt atgcgggctt tgtattgctt tctgtatcct acaaatgagt
     1141 gaaatttatg aaaaaggcta aaatactttc tggcgtatta ttactgtgct tttcgtcccc
     1201 attaatttct caggctgcga cactggacgt acgtggtgga tatcgtagtg gaagccacgc
     1261 ctatgagact cgactcaaag tcagtgaggg atggcaaaat ggatggtggg caagcatgga
     1321 aagtaatacc tggaatacca ttcatgataa taaaaaggaa aatgccgcac tcaatgatgt
     1381 tcaggttgaa gttaattacg caattaaact tgatgatcaa tggacggtac gcccgggaat
     1441 gttaacgcat tttagcagca acggcacacg ttacggaccc tacgtaaaac tgtcctggga
     1501 cgcgacaaaa gatcttaatt ttggcattcg ctatcgttac gactggaaag cttaccgaca
     1561 acaagactta tccggtgata tgtctcgtga taacgttcat cgttgggatg gatatgtcac
     1621 ttaccatatt aatagtgatt tcaccttcgc atggcaaacg acgctataca gcaaacagaa
     1681 cgattatcgc tatgcaaacc ataagaaatg ggcgacggaa aatgcatttg ttctacaata
     1741 ccatatgacg cccgatatta cgccatacat agaatatgac taccttgacc gtcagggtgt
     1801 ttacaacggc agagataatt tatcggaaaa cagttatcgc attggtgtgt catttaaact
     1861 gtagtagaca ggagacagtc acaatgaata aaacaataac ggcgcttgct atcatgatgg
     1921 cttcatttgc cgcaaacgcg tctgtattac cggaaactcc tgtgccattt aaaagtggta
     1981 ccggagcaat tgataacgac actgtctaca ttggtttagg tagcgcaggt acggcatggt
     2041 acaagctgga tacacaggcc aaagataaaa aatggacagc gttagctgca ttccctggtg
     2101 gaccaagaga tcaagcaacc tcggcattta ttgatggtga tctgtatgtg tttggcggca
     2161 ttggcaaaaa tagcaagggc ttgactcagg tatttaatga cgtacacaaa tacaacccca
     2221 aaaccaatag ctgggttaaa ttgatgtcgc acgcgccaat gggcatggcg ggccatgtga
     2281 cttttgtaca caacggcaaa gcttatgtta ctggcggtgt taaccagaat atcttcaatg
     2341 gctattttga agatctcaac gaggctggaa aagattcaac cgctatagat aaaatcaacg
     2401 ctcactattt tgacaaaaaa gcagaagatt atttcttcaa taagtttctg ttgtcttttg
     2461 atccctcaac ccagcaatgg agttacgctg gcgaatctcc ctggtacgga acggctggtg
     2521 cggcggttgt gaataaaggt gataaaacct ggcttattaa tggcgaagcc aaacccggat
     2581 tgcgaacgga tgccgtattt gaacttgatt tcaccggtga taatttaaaa tggaataggc
     2641 ttgctcccgt ctcatcacca gatggcgtcg ctggcggttt tgcggggata agcaatgatt
     2701 ctcttatatt tgccggaggg gccggattca aaggttcacg agaaaattac cagaacggta
     2761 agaactatgc gcatgaaggc ctgaaaaaat catatagcac tgatattcat ctttggcata
     2821 acgggaaatg ggataaatcg ggtgaattat cgcaaggtcg ggcctacgga gtatcattgc
     2881 cctggaataa tagtctattg attattggcg gtgaatctgc aggcggcaaa gcggtgacgg
     2941 attcagtttt gatctctgtg aaggataata aagtcacagt acaaaactaa cgcttcaggg
     3001 ccccggtaaa gggccctgct atcaatttgt catttcaatt acgcgaaaat tatatgaacg
     3061 caataatatc gcccaattat tactatgttc ttaccgttgc tggtcagtct aatgccatgg
     3121 cgtatggcga aggactgcca ttaccggaca gggaagatgc gcctcatccc agaatcaaac
     3181 aattagcgag atttacgcat acgcatcccg gaggcccgcc atgtcacttt aacgacatta
     3241 ttccactgac tcactgccca cacgatgttc aggatatgca gggttatcac catcctctgg
     3301 caacgaatca tcaaacacag tacggcaccg ttggccaggc actgcatatt gcacggaaat
     3361 tactgccctt cattcctgat aatgcaggga ttctcatcgt cccgtgttgc cgtggcggat
     3421 cggcttttac cgcgggcagc gaggggacat attcagaacg gcacggagcc agccatgatg
     3481 cttgtcgttg gggaacggat accccgctct accaggattt agtcagcaga acgcgagccg
     3541 cactggcaaa aaatccgcat aacaaattcc tcggcgtatg ctggatgcaa ggcgaatttg
     3601 acttaatgac cagtgactac gcgtcacacc ctcaacactt taatcatatg gttgaagcct
     3661 ttcgtaggga tctaaaacaa ttccattctc agcttaataa tattactgcc gcgccgtggt
     3721 tttgcggcga taccacctgg tactggaaag aaaatttccc tcatgcgtat gaagctattt
     3781 atggcaatta tcaaaataat gttttagcca atattatttt cgtcgacttc cagcaacaag
     3841 gtgaaagagg actgacgaac gcgcctgatg aagatccgga cgatttaagc acgggatatt
     3901 tcggttcagc gtaccggtca gcggagaact ggacgacgtc actgcgaagc agtcatttca
     3961 gcgcggcagc ccgtcggggg attatttctg acagatttgt agaagcaatt ttgcagtttt
     4021 ggcgcgaaag gtgagcgggg agtttattca tgggggatgt ccttgtccat tcccagagca
     4081 gacaacaaaa aacaaatgag atcaaggtaa tatctcttca cttgcgggct cgaacagcag
     4141 gcaattgcca atataataat ctggcacaag ggtgaaaaac gcgcaccgca taaaccgttg
     4201 ttattgctta cagattagcc ggatgcctta atagacatcc gcgccttttc ggttatggct
     4261 cggaaatcta cgaacatcta cacagtttac tggaacgttt tgggccacag cgttcgcagc
     4321 accgtcctga tatgccgttc tggcgattat aagtcgacgg attctggcaa atagacgatg
     4381 atgatatgct taatgatgtt caaagaaatt aggccattat tatattattg cttgcatttt
     4441 ctttcattcc taaaagcacc cgccattaat cccaggcgca ttatgcaaag gaaaatgatt
     4501 aggtaaacaa taagatttat aatcaggaaa ggcgactcgc aataaaacgg aaagtcgcct
     4561 taacattggt aaaatatgcc ctttactact cctgtatcat gaacggctca tcacatttaa
     4621 agctgacgtt gatccagact accatatatt gcctttattt cattttttac gccttcgcca
     4681 cggtacacca aagacgtatc gtatcgttga tacttatctt cccgtgcagc actgaaccag
     4741 ttaaaagatc cgacacacag cagttcttca tcctcaatca caattttgct gtggacacga
     4801 ttaaccaatt tcgtagcgat acccatctta ttgagctttt caacagcatc attcagcaga
     4861 tgttgtttct cctgacgctt atcatcatcg acatgcgcta tattgcagtt tttatccgtc
     4921 accacggtaa tatcaatgcc ccgggaacgg gccaaagcca ttgatgccag aaatcccgtt
     4981 tgctccactt tttgccaaga taaccaaggg gaaataatcg ttattttctt ttgagctccg
     5041 gcaagagtct tgttcaaaaa tccatcatgc tgctccacac catgcagcgt tgaaatttgt
     5101 gtatgtgcgg aaattaaatc ctgtcgtttc tgaaactcaa attgcaacgc attattatct
     5161 gaagaaaaga gatattttgc caataaccct cgcggcgaaa atgcgggctg catctcgata
     5221 aggtccatat cgccaaatac cagaaaacta tctttagcgc gtgagacagc aacattgagg
     5281 atactgctgt tgctatcaag aaacctgcca tcttcatgtt ttgagtagac aggagaaaag
     5341 agaacaatcg ccctttccgc cccctgcaag gagtgcacag tccccactgt cagtgaaccc
     5401 tgctcgtctt tgccattaat ttccagctta cgcaatgacg ttttgatagc attaacctgc
     5461 gccgaaaatg gcgtcacaac accaacaact ttgtacagtg gttccccgta atggcgctct
     5521 atatcatcct tatgtgccac cagccatgct gctattgttt cagcttcaag agggttataa
     5581 cggcttcctc catttggctt catgcctcta ccatcaatat gtaaatatcc cattgcgggg
     5641 aaaatcgtcc ctttttccat ccctctttta ggctgcaact taccgtgata gcaaagtgag
     5701 ttacagtagc cg
//
LOCUS       DAFGPF010000203         5637 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFGPF010000203 DAFGPF010000000
VERSION     DAFGPF010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5637
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.204"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            100..321
                     /locus_tag="LSX49_004962"
     CDS             100..321
                     /locus_tag="LSX49_004962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBL7171230.1"
                     /translation="MKIITRGEAMRIHQQHPTSRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            340..984
                     /locus_tag="LSX49_004963"
     CDS             340..984
                     /locus_tag="LSX49_004963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of toxin-antitoxin stability system"
                     /protein_id="HBL7171231.1"
                     /translation="MSSIITITVYTLDELSCPARGKARDWYRQHHADSNWYENVYEDF
                     REVCGIFGIDLRQRVFRLSNGRFMEEPCIWFSGFCSQGDGACFEGRWHWQPATPRKIR
                     EYAPQDRELHRIADTLQAVQKRNFWQLQAEISHRGRYCHPYSMDITVTRNSPTGQAMT
                     TDAEAAVSEALRDLAFWLYRQLENKYDWLTSDTAVDEALLINEYTFTEAGLRAG"
     gene            1034..1402
                     /locus_tag="LSX49_004964"
     CDS             1034..1402
                     /locus_tag="LSX49_004964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HBL7171232.1"
                     /translation="MSDTLPGTTLPDDNKDLPWWGLPCTVTPCFGACLVQEGNRLHYL
                     ADRAGIRGRFSDADAYHPDQAFPLLMKQPELMLTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCDYVYLAVYPTPEMKN"
     gene            1491..1868
                     /locus_tag="LSX49_004965"
     CDS             1491..1868
                     /locus_tag="LSX49_004965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HBL7171233.1"
                     /translation="MKTLPDTHVRAASRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYAQVRTDQPGFSAGAPSQLINSIDILRARRATG
                     LMTRNNYRMVNNITQGKHPEAKR"
     gene            1865..2353
                     /locus_tag="LSX49_004966"
     CDS             1865..2353
                     /locus_tag="LSX49_004966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171234.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDVDGVELAELINVVCDNGYS
                     LRVVDESDRTSTDSIPPSAALSGIRCSTAHITETDNAWLYSLSHQTNDTGESEWIHFT
                     GSGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLTRRYGVSLIHLDASTECLPDLPTF
                     DW"
     gene            2370..2567
                     /locus_tag="LSX49_004967"
     CDS             2370..2567
                     /locus_tag="LSX49_004967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HBL7171235.1"
                     /translation="MKSLTTETALYILIAWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IKQAREDIRTLRQLQLLQQNR"
     gene            2652..3497
                     /locus_tag="LSX49_004968"
     CDS             2652..3497
                     /locus_tag="LSX49_004968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HBL7171236.1"
                     /translation="MSDITISRPELVNGHTDVICSTSIRHILAVRKSALLQIDTLIRQ
                     LAEISVLTESIGGKTALDWAMKQDFRCGCWLMEKPETAMKAITRNLDREIWRDLMQHS
                     GMLSLMDAQAHDTWYRSLEYDNFPEISEANILSTFEQLHQNKDDVFERGVINLFRGLS
                     WNYKTNCPCKFGNKIIVNNLVRWDRWGLHLITGQQADRLADLERMLHLFSGKPIPDSR
                     ENIIIRLDDHIRSVQGKACYEDEMFSIRYFKKGSAHITFRKPELVDRLNDIIARHYPN
                     VLADR"
     gene            3566..3961
                     /locus_tag="LSX49_004969"
     CDS             3566..3961
                     /locus_tag="LSX49_004969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000208382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL7171237.1"
                     /translation="MTTKDRIQSRLNRSKRYVFTRDDFRDIAGYDQVGRALRTLVNEG
                     KLMKVGYGVYTKARRNIITGKIMPAAPGGSAAVITEALERLNIRYRLAGATECYNKSQ
                     STQIPVSLGIKTPSRFKRMLIVGKSKINA"
     gene            3954..4887
                     /locus_tag="LSX49_004970"
                     /pseudo
     CDS             3954..4887
                     /locus_tag="LSX49_004970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536504.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
     gene            5319..5474
                     /locus_tag="LSX49_004971"
     CDS             5319..5474
                     /locus_tag="LSX49_004971"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171238.1"
                     /translation="MAALVVTWFNPVKEAFYMHLPAAGKTKKVALVDCMRKLLTILNA
                     MLRKNEE"
BASE COUNT         1552 a         1417 c         1332 g         1336 t
ORIGIN      
        1 ccaggttttc tcctttgccg aacatggtct gctttaaccc gtcacaacca catcacacct
       61 gttttcactt ttatcttctg tcttcagagg tatcccatta tgaaaattat cactcgtggt
      121 gaagccatgc gtattcacca acaacatccg acatcccgtc ttttcccgtt ctgtaccggc
      181 aaataccgct ggcacggcag cactgaagcg tataccggtc gtgaagtgca ggatattccc
      241 ggtgtgttgg ccgtgtttgc tgaacgtcgt aaggacagtt ttggcccgta tgtccggctg
      301 atgagcgtca ccctgaactg aatcaggacg ggcattcaga tgagcagcat tatcaccatc
      361 acagtgtata cgctggatga actttcctgc ccggcacggg gaaaagcccg cgactggtac
      421 cgtcagcatc atgctgacag caactggtat gaaaacgtgt atgaagactt cagggaggtc
      481 tgtggcattt tcgggattga cctccgccag cgcgttttcc ggctcagcaa tggcaggttt
      541 atggaagagc cgtgcatctg gttcagcgga ttctgcagcc agggggacgg agcctgtttt
      601 gaagggcgct ggcactggca gccagcgaca ccccggaaaa tcagggaata tgcccctcag
      661 gaccgtgagc ttcatcgtat cgcggatacc ctgcaggcgg tgcagaaacg taacttctgg
      721 cagcttcagg ctgaaatcag tcaccgggga cgttactgcc atccgtacag catggatatc
      781 accgtcaccc ggaacagtcc gactggtcag gcaatgacaa ccgatgcgga agccgctgtc
      841 agcgaagccc tgcgcgacct ggccttctgg ctgtaccgcc agctggaaaa caagtacgac
      901 tggctgacct cagacaccgc tgtggatgag gcccttctca tcaacgaata taccttcacc
      961 gaagccggtc tgcgcgccgg ctgacccgtc atcgttaaac tatcattcac cgattttctg
     1021 tgaggatttt atcatgtcgg acacactccc cggaacaacg cttcccgacg acaacaaaga
     1081 cctcccctgg tgggggctgc cctgcaccgt gacgccctgt ttcggggcct gtctggtgca
     1141 ggagggtaac cggttgcatt accttgccga ccgcgccggt atcagaggcc ggttcagcga
     1201 tgcggatgcg taccatccgg accaggcctt tccgctgctg atgaaacaac cggaactcat
     1261 gctcaccagc ggtgaactga atccccgcca tcagcatacc gtcacactgt atgcgaaagg
     1321 actgacctgc gaagccgata ccctgggctc ctgtgattac gtttatctgg ctgtttatcc
     1381 gacgcccgaa atgaaaaatt aactctccag aatagccttc tgctacggcc tggtgttttc
     1441 accacgccac ttttccattt ttatatctgc atatcaggaa aatcttcagt atgaaaacat
     1501 tacccgacac acacgtacgg gcggcatcgc gctgcccgtc tcccgtcacc atctggcaga
     1561 cactgctcac ccgactgctg gaccagcact atggcctcac gctgaatgac acaccgttcg
     1621 ctgatgaacg tgtgattgag cagcatattg aggcagggat ttcactgtgt gacgcggtga
     1681 actttctcgt tgaaaaatac gcgcaggtac gtaccgacca gccgggattc agcgcaggag
     1741 ccccgtcgca gttaatcaac agcattgata ttctccgggc tcgcagggcg accggcctga
     1801 tgacccggaa caattacaga atggtaaata acattaccca gggcaagcat ccggaggcaa
     1861 aacgatgaaa ctggccctga cgctggaagc tgacagcgtt aacgtacagg cactgaacat
     1921 ggggcgaatt gtcgttgacg tcgatggtgt tgagcttgcc gaactgatta acgtggtctg
     1981 cgataatggc tactcccttc gtgttgttga tgaatctgac cggacctcaa cagacagcat
     2041 acccccctct gctgccctga gcggtatacg ctgtagtacc gcgcatatca cggaaacaga
     2101 caacgcctgg ctgtactcgc tgtcgcatca gacgaatgac accggcgaat cagaatggat
     2161 tcattttaca ggtagcggat atctgttacg taccgatgcg tggtcatacc cggttctgcg
     2221 gcttaaacgc ctggggctgt caaaaacgtt ccgccgtctg gttgtcacac ttacccgacg
     2281 ttatggcgtc agtctcattc atctggatgc cagcactgaa tgcctgccgg atttacccac
     2341 tttcgactgg taacccggaa attcacaaca tgaaatcatt aaccacggaa acagcgctgt
     2401 atattctgat tgcgtggctg caggacaata ttgactgcga atcagggatt atcttcgaca
     2461 acgatgagga taaaacggat tcagcagcac tgctgccctg cattaaacag gccagggaag
     2521 atatccgtac cctgcgccaa ctgcagcttc tgcaacagaa ccggtgagtc ttactcacca
     2581 gacttcattc cactgacgcc agcctgaata cggctggcgt tttcgtttat aaaccaaaag
     2641 gaaaaacgat gatgtcagat atcacaatct cccgcccgga actggtcaac ggacatacgg
     2701 acgttatctg ctcaaccagt atccgccaca ttctggctgt acgaaagagt gcgctgctgc
     2761 aaatcgacac acttatccgg caactggcag aaatctcagt actgacagaa agtattggag
     2821 gtaaaaccgc cctggactgg gcgatgaaac aggattttcg ctgcggctgc tggctcatgg
     2881 agaaaccgga aaccgcaatg aaagccatca cccgcaatct cgatcgcgaa atctggcgtg
     2941 acctgatgca acattccggg atgctgtcat taatggatgc gcaggcccat gatacatggt
     3001 accgctcact ggagtacgat aactttccgg aaatcagcga ggcgaatatc ctgagtacgt
     3061 ttgaacaact gcaccagaat aaggatgacg tgtttgagcg aggtgtgatc aacctcttca
     3121 gagggctgag ctggaattac aaaaccaatt gcccctgtaa atttggcaat aaaattatcg
     3181 tcaacaatct ggtgagatgg gaccgatggg gattgcatct tatcaccggg caacaggcag
     3241 atcgactcgc tgacctggaa agaatgctgc atctgttcag cggcaaaccg atccccgaca
     3301 gccgggaaaa tatcatcatt cggctggatg atcacatccg ctccgttcag ggcaaagcgt
     3361 gctatgaaga tgagatgttc agcatcagat actttaagaa gggctccgca cacatcacgt
     3421 tcaggaaacc agaactggtt gacaggctaa atgacataat tgccaggcac tatccaaatg
     3481 tattagcaga caggtaatgt ggccttgccc cgctattaaa catgtcatat ttttgctatc
     3541 attgtgaaaa tttttcggag gaaacatgac tacaaaagac cgtattcagt cccgactgaa
     3601 ccgttcaaaa cgttatgtgt tcacccggga tgatttcagg gatatcgctg gctatgatca
     3661 ggttggcaga gctcttcgta cactggtaaa cgaaggtaag ttgatgaaag tgggctatgg
     3721 tgtttacacc aaagcccgtc gtaacatcat cactgggaaa atcatgcccg cagcgcctgg
     3781 gggctctgct gcagtaatta cagaggccct ggagcgcctg aatatcagat accgtctggc
     3841 aggagcaacg gaatgctaca ataaaagtca gtccacacaa attcctgtat ctctggggat
     3901 aaaaacacct tctcgattta aaagaatgtt aatagtaggg aaaagtaaaa tcaatgcctg
     3961 aattaacatc attatttcct gacgttgccg atgcactgga tattgaatct gtcgctatcg
     4021 tcgaaaaaga ttattttgtg gttgatcttt taagattatt aaaagaaata aaaccagaaa
     4081 cacatactct cgtgtttgca ggaggtaccg cattatcaaa agcaggtatc tcgctaaaca
     4141 gaatgtcaga agatattgat ataaagctcg tgccaacaga gaactttatg caaaatggca
     4201 gagacaagag aagaaaaatt cgcaaggaaa tcgtgcaaat aatcacggat gttattcata
     4261 attctgacat tttcagcttg gataatgaaa acgcccgtat aacacgtgat gagtatcgtt
     4321 ataacgaaat ctcggtacgt tatccccaga catttgcaca agtcccctgt cttcgtccat
     4381 ttattaagct ggagttgatg gaaagcactc tgctggaaca tccggaaagc agagatattt
     4441 attcccttgt cacggagtta acgggtaaag gtacacctgt aacagcattc ccctgtgcca
     4501 ccattttatc cactcaggct gaaaagctca tctccatgat gcgaagaaca gcagcacatc
     4561 ttcgtaatcc cgaacaacag gatgatgagt ttctggtacg tcacatttac gacaactact
     4621 gcattgtcag ggaaaaaggt gtgaatgttc ctgtattgaa aaattttgtt cagatatgta
     4681 ttcagctatg gtaaccagta cccacaattt tgtagctcac cagttgatga acttaagaaa
     4741 gggctggatg cactccggga ttatcctgta cacaaattgc gctttcaacg atttgttaaa
     4801 ccgatggtat ttggtaatac acagattaac tgggaagaag cctattccag tttcagacaa
     4861 acagcgctaa gtgttctgac cagctaacaa acgcgttaag tacgattcca caattcagca
     4921 tatcgaacca gaccaaatga ttacagcaaa gcacaaaaaa gagggattat agcgtcaaaa
     4981 gaattcgaat tgcacatggg ggcctcattg gtggcctcaa aaacaacaaa tacaaaataa
     5041 tctatataaa acaatttgtt atacaatcag tttcattccg attccgggca ccactaattc
     5101 ttaagaaccc gcccacaagg cgggtttttg cttttggatc tttatataaa ataaacttgg
     5161 gtgcataacg ccatcaggtc ttaaacactc ccgaatcatc aataaacatc ccccgctaac
     5221 aaaacacagt tcagttcaca taacatccct gttatcccac acatatctgc tggccgaacg
     5281 acgccagtgc gcgtacggag gcaagagcag ccctgcacat ggcagcgctt gtggtaacct
     5341 ggtttaatcc ggtgaaagag gcgttttaca tgcatctgcc agcagccgga aaaaccaaaa
     5401 aagtggcgct ggttgactgt atgcgtaaat tgctgaccat cctgaacgca atgctcagaa
     5461 agaacgaaga gtgaaatgaa tcgtagcatc atgttgctcc ataattttta cgttcaagac
     5521 agttgattat cggcgcatat gactcaaaaa gagcctgatg attgcctctt ttccataggc
     5581 tctttctctg aagtgaagga aggcccggaa gaaagcactc gctggcatac gtgactc
//
LOCUS       DAFGPF010000204         5482 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFGPF010000204 DAFGPF010000000
VERSION     DAFGPF010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5482
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.205"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            2..343
                     /locus_tag="LSX49_004972"
     CDS             2..343
                     /locus_tag="LSX49_004972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171239.1"
                     /translation="MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTAT
                     FGNYAYLRAEKLGQLDDFFIHVCQLVALITIGLLFIGVLNAPINAYEMVIYPIAFFVC
                     LFGQMRLFRSA"
     gene            389..826
                     /locus_tag="LSX49_004973"
     CDS             389..826
                     /locus_tag="LSX49_004973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaB family inner membrane protein"
                     /protein_id="HBL7171240.1"
                     /translation="MDNKISTYSPAFSIVSWVALIGGIVTYLLGLWNAEMQLNEKGYY
                     FAVLVLGLFSAASYQKTVRDKYEGIPTTPIYYMTCLTVFIISVALLLVGLWNATLLLS
                     EKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKETQVTQEEYSE"
     gene            complement(868..1863)
                     /gene="wecH"
                     /locus_tag="LSX49_004974"
     CDS             complement(868..1863)
                     /gene="wecH"
                     /locus_tag="LSX49_004974"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase WecH"
                     /protein_id="HBL7171241.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVINAHSVSPITWDIAN
                     VLNSASRVSVPLFFMISGYLFFGERSAQSRHFLRIGLCLFFYSAIALLYIALFTSINV
                     ELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMVVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLYTRTICGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAVSLLLSMLVQRIDRNRLVS"
     gene            2038..2337
                     /locus_tag="LSX49_004975"
     CDS             2038..2337
                     /locus_tag="LSX49_004975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YsaB family lipoprotein"
                     /protein_id="HBL7171242.1"
                     /translation="MMMNAFFPAMALIVLVGCSTPPPVQKAQRVKVDPLRSLNMEALC
                     KDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR"
     gene            2432..3343
                     /gene="glyQ"
                     /locus_tag="LSX49_004976"
     CDS             2432..3343
                     /gene="glyQ"
                     /locus_tag="LSX49_004976"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBL7171243.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            3353..5422
                     /gene="glyS"
                     /locus_tag="LSX49_004977"
     CDS             3353..5422
                     /gene="glyS"
                     /locus_tag="LSX49_004977"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBL7171244.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRV
                     ADISLLQ"
BASE COUNT         1394 a         1340 c         1412 g         1336 t
ORIGIN      
        1 tatgaaaacc tcaaagactg tggcaaaact attatttgtt gtcggggcgc tggtttatct
       61 ggttgggcta tggatctcat gcccattgtt aagtggaaaa ggctattttc ttggcgtgtt
      121 aatgacggca acttttggca actatgcata tcttcgcgca gaaaaacttg ggcaactgga
      181 tgattttttt atccacgtct gtcagttggt agcgttaatc actatcggtc tcttgtttat
      241 cggtgtttta aacgcaccta tcaatgctta tgaaatggtg atctatccca tcgccttttt
      301 tgtctgcttg tttggtcaaa tgcgtttgtt tcgctcggca tgagcaacat aaagttctta
      361 cacattcagg aatgaaagga atactgtgat ggacaacaaa atatcaacct attctccggc
      421 atttagtatt gtttcatggg tagcccttat tggcggtatt gttacctatc tgttaggact
      481 atggaatgca gagatgcagt taaatgaaaa agggtattat tttgccgtac tggtattagg
      541 tttgttttcc gcggcgtctt atcaaaagac cgttcgggac aagtatgaag gcatacctac
      601 cacccccatt tattatatga cttgcctgac ggtctttatt atctctgttg cgttgttgct
      661 ggtaggtcta tggaatgcaa cgttattact cagcgaaaaa ggcttttatg ggctggcttt
      721 cttcttaagc ttgtttggtg cagtagcggt gcagaagaat attcgtgatg ccggaataaa
      781 cccaccaaaa gaaacacagg ttacccagga agaatacagc gaataattca cgtaagcccg
      841 gtcagtccaa tgtgaccggg cttctactta actcactaat ctgtttctgt cgattcgttg
      901 taccagcata gaaagtaata aactcactgc cagcgtcgca caaaagatcc aaataatatc
      961 cagtattggc cagtttttaa gctcaatccc ccgggtgcgc agtgcatgga taatcaatgc
     1021 atggaacccg tatataccta acgaatggcg ggagattaag ccaagtccgc aaatggtacg
     1081 cgtatacagc gtgtttttaa ccagagtcaa taacgcgatt gcgcagataa aaaccatcgg
     1141 cccacagtaa agataccagg tatcggcaaa atttccgcgc cactgtaatt catataatgt
     1201 cccacgagag ataataaaaa cccccgtcgc aaacagtgcg gcgctcaccc acgacagtgc
     1261 tttatgctgt gtgtccatca tccctatagc gcggcccaac atgccataaa ggatgtagta
     1321 aaaagtatcg ccattgatat ataagttaat tggcagccat tcaaaaccgt cgattttctg
     1381 cggcacggtg tttgggttag cgatgatacc aatcaccacc attagcacca gcaacatttt
     1441 tccgccgacg ttcttcacct gaatcagcgg tgaaaccaga taaatcactg caatcgcgaa
     1501 gaaaaaccat aaatggtaaa acactggctt ttgcagcagg tttttcagcg ctaactccac
     1561 attgatggag gtaaacagcg caatgtagag cagcgcgatt gcgctataaa aaaacaggca
     1621 taagccgata cgcaagaaat gacgcgactg ggcgctgcgt tcgccaaaaa agagatagcc
     1681 ggaaatcatg aaaaatagcg gcacgctgac acgagaggca gaattcagaa cattggcgat
     1741 atcccaggtg atggggctaa cactatgagc attgatcaca taccaggtag tggtgtgaat
     1801 catcaccacc attaaacacg ctatccctcg caggttatca atccagtaaa ttttgggctg
     1861 catctgtgtc tctgtatctg gttaaaaaaa gtctgaccga taaatcattc agttggcgca
     1921 ctggaataat ctgagtttta tcactacagc ttatagaggc ttaaggaaat tcgtaagata
     1981 tcagccacta taccgatata aataataaga ctcacctgca aaccagacgg taatttaatg
     2041 atgatgaacg ctttctttcc ggcaatggcg cttattgtgc tagtgggttg ttctacaccg
     2101 ccacccgtgc agaaagcaca acgggtaaag gttgatcctc tgcgttcgtt gaatatggaa
     2161 gcgttatgca aggatcaggc ggcaaaacgt tataacaccg gcgagcaaaa aatcgacgtc
     2221 accgccttcg aacagttcca gggaagctat gaaatgcgcg gttatacctt ccggaaagag
     2281 cagtttgtct gttcttttga cgcggatggc cattttttgc atctttccat gcgttaagcc
     2341 ctgctttttc ccgtttcgta ctgtatatct tccatccagc gggtatactg atcccttcct
     2401 ttaaatccac acgtatccag cacgaaataa tatgcaaaag tttgatacca ggaccttcca
     2461 gggcttgatc ctgaccttac aggattactg ggctcgccag ggctgcacca ttgttcaacc
     2521 attggacatg gaagtcggcg cgggaacctc tcacccaatg acctgtctgc gcgcgctggg
     2581 gccagaaccg atggcggctg cttatgttca gccttctcgt cgcccgaccg atggtcgcta
     2641 cggcgaaaac cccaaccgtt tacagcacta ctatcagttc caggtggtca ttaagccatc
     2701 gccggacaat attcaggagc tgtacctcgg ttctctgaaa gagctgggca tggacccgac
     2761 catccacgac atccgtttcg tggaagataa ctgggaaaac ccgacgctgg gtgcctgggg
     2821 gctgggctgg gaagtgtggc taaacggcat ggaagtgacg cagttcactt acttccagca
     2881 ggttggtggt ctggaatgta aaccggttac cggtgagatc acctacggtc tggaacgtct
     2941 ggccatgtac attcagggcg tagacagcgt ttacgacctg gtctggagcg acggcccgct
     3001 gggtaaaacc acctacggcg acgtgttcca tcagaacgaa gtggagcagt ccacttacaa
     3061 cttcgaatac gcggatgtgg acttcctgtt cacctgcttc gagcagtacg agaaagaagc
     3121 gcagcaactg ctggcgctgg aaaatccgct gccgctgcca gcctacgagc gtattctgaa
     3181 agccgcccac agcttcaacc tgctggatgc gcgtaaagcc atctccgtca ccgagcgtca
     3241 gcgctatatt ctgcgcattc gcaccctgac caaagcagtg gcagaagcat actacgcttc
     3301 ccgtgaagcc ctcggcttcc cgatgtgcaa caaagataag taagaggcgg ctatgtctga
     3361 gaaaactttt ctggtggaaa tcggcactga agagctgcca ccaaaagcac tacgcagcct
     3421 ggctgagtcc tttgctgcga actttactgc ggagctggat aacgctggcc tcgcacacgg
     3481 caccgttcaa tggtttgctg ctccgcgtcg tctggcgctg aaagtcgcta acctggcgga
     3541 ggcgcaaccg gatcgtgaaa tcgaaaaacg tggtccggca attgctcagg cgttcgacgc
     3601 tgaaggcaaa ccgagtaaag cggcagaagg ttgggcgcgt ggttgcggta ttaccgttga
     3661 ccaggctgag cgtctgacta ccgataaagg cgaatggctg ctgtatcgcg cccatgtgaa
     3721 gggcgaaagc accgaagcac tgctgccgaa tatggttgcg acttcgctgg cgaaactgcc
     3781 gatcccgaaa ctgatgcgtt ggggcgcaag cgacgtgcac tttgtgcgtc cggttcacac
     3841 cgtgaccctg ctgctgggcg acaaagttat tccggctacc attctgggta ttcagtccga
     3901 tcgcgtgatt cgcggccacc gctttatggg cgagccggaa ttcactatcg acaatgccga
     3961 tcagtatcca gaaattctgc gtgagcgcgg gaaagtcatc gccgattacg aagaacgtaa
     4021 ggcgaagatt aaagccgatg ctgaagaagc agcacgtaag attggcggta acgctgattt
     4081 aagcgaaagc ctgctggaag aagtggcttc gctggtggag tggccggtcg ttctgaccgc
     4141 gaaattcgaa gagaaattcc tcgcggtgcc gtctgaagca ctggtttaca ccatgaaagg
     4201 tgaccagaag tacttcccgg tgtatgcgaa cgacggcaaa ctgctgccga actttatctt
     4261 cgttgccaac atcgaatcga aagatccgca gcagattatc tccggtaacg agaaagtcgt
     4321 tcgtccacgt ttggcggatg ccgagttctt cttcaatacc gaccgtaaaa aacgtcttga
     4381 agataacctg ccgcgcctgc aaaccgtgtt gttccagcaa cagttgggga cgctgcgcga
     4441 caaaactgac cgcattcagg cgctggccgg ctggattgct gaacagattg gcgctgacgt
     4501 taaccacgct acccgtgcgg gcctgctgtc taagtgtgac ctgatgacca acatggtctt
     4561 cgagttcacc gacacccagg gcgttatggg gatgcactac gcgcgtcacg atggcgaagc
     4621 ggaagacgta gctgtcgcgc tgaatgagca gtatcagccg cgctttgccg gtgatgacct
     4681 gccgtctaac ccggtagcct gtgcgctggc gattgctgac aagatggata ccctggcggg
     4741 tatcttcggt atcggccagc atccgaaagg cgacaaagac ccgtttgcgc tgcgtcgtgc
     4801 cgcacttggc gtgctgcgta ttatcgttga gaagaacctc aaccttgatc tgcaaacgct
     4861 gaccgaagaa gcagtgcgtc tgtatggcga taagctgact aatgccaacg tggttgatga
     4921 tgttatcgac tttatgctcg gtcgcttccg cgcctggtat caggacgaag gttacaccgt
     4981 tgacaccatc caggcggtac tggcgcgtcg tccgactcgt ccggctgatt tcgatgcccg
     5041 tatgaaagcg gtatcgcact tccgtaccct ggaagcagct gcagcactgg cggcggcgaa
     5101 caagcgtgta tctaacatcc tggcgaaatc tgatgaagtg ctgagcgatc gcgtgaatgc
     5161 ctctactctg aaagagccgg aagaaattaa actggcgatg caggttgtgg tgctacgtga
     5221 caagctggag ccgtactttg cggaaggtcg ttaccaggat gcgctggtcg aactggctga
     5281 gctgcgtgaa ccggtcgatg ctttcttcga taaagtgatg gtcatggttg atgataaaga
     5341 attgcgtatc aaccgtctga ccatgctgga aaaactgcgc gaactgttcc tgcgcgttgc
     5401 ggatatttcg ctgttgcagt aataacgccg ttattaaaaa gcctgccatc tggcaggctt
     5461 tttttatcgc taaataatac ag
//
LOCUS       DAFGPF010000205         5303 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFGPF010000205 DAFGPF010000000
VERSION     DAFGPF010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5303
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.206"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            290..1141
                     /locus_tag="LSX49_004978"
     CDS             290..1141
                     /locus_tag="LSX49_004978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL7171245.1"
                     /translation="MQKVKLNNGIEMPLLGFGVFQMTDAAECERAVIDAINSGYRLID
                     TAASYQNEIQVGNALKQSGIARNELFVTTKLWLQDTSYEGAKAQFERSLNRLQLDYVD
                     LYLIHQPYGDVHGAWRAMEELQQAGKIRAIGVSNFHPDRLADLIAFNNVVPAVNQVEV
                     NPFNQQLQAVPWMQSRGIQPEAWAPFAEGKNGLFQHPVLTAIGEKYGKSVGQVVLRWI
                     YQRGIVSLAKSVRKERMEENINILDFELSPEDMLQITALDTATSAFFSHRDPAMVEWL
                     TGRKLDV"
     gene            1168..2157
                     /locus_tag="LSX49_004979"
     CDS             1168..2157
                     /locus_tag="LSX49_004979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL7171246.1"
                     /translation="MQKRYLGKSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAV
                     ERGVTFFDTAEVYGPYLNEEVVGEALKPFRDRVVIATKFGFTFGDDNKQQILNSRPEH
                     IREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
                     TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPG
                     TTFGKDDYRSTVPRFAAQAIEANEKLVTLLGELAADKGVTSAQIALAWLLAQKPWIVP
                     IPGTTKLNRLEENLAAADIVLSQKDTQQITEALETIKIVGERYSPEHQARVGR"
     gene            complement(2188..3081)
                     /locus_tag="LSX49_004980"
     CDS             complement(2188..3081)
                     /locus_tag="LSX49_004980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7171247.1"
                     /translation="MLKENFNELQIFLVVARERSFTKAAGKLGVSQSALSHAMKALEE
                     RLNIRLLTRTTRSVAPTEAGERIIACLEPRIDELEQELESLIQLNGTPSGNIRLSAGE
                     HAARSLVWPKLKPFLREYPEINVELVVDNGFVDIVEGRFDAGIRLGENVDKDMVAVRI
                     GPDMRMAVVGAPAYFAANPAPETPHELQNHRCINMRLPTAGGLYHWEFEREGKPLRVK
                     VDGQLTCSPLPERIDAALSGFGIACVPEDMVQEYIKSGKLIQVLQEWCPTFPGYYLYY
                     PSRKQHPPAFALLIDALRYTE"
     gene            complement(3281..4207)
                     /locus_tag="LSX49_004981"
     CDS             complement(3281..4207)
                     /locus_tag="LSX49_004981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL7171248.1"
                     /translation="MMKIEPSILPSLAWFALIVRAGSFSRAASEMGITRAALSQNLKS
                     LEERLNTKLIYRTTRNMSLTEEGQHLYEVLVSALGQIDDALKDVGDTQLEPTGLLRIN
                     SSRVAARMLVEPHIGEFLTRYPKTKIELIMDDGLSNIIADGCDVGIRLEQGLDEHMTA
                     IPVSPLIKLVTVASPDYLKEHGIPETPQELSNHNCLRLRHKSSGALSAWEFSNVVGGN
                     EEFEIEVSGKYISNDDESMIRMALNGTGIIQHLDFAIAEHINAGKLQPILEDWAVSFP
                     GFYIYVSSRVRMPSKVRAFIDFMVEKRVKIES"
     gene            4364..5284
                     /locus_tag="LSX49_004982"
     CDS             4364..5284
                     /locus_tag="LSX49_004982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7171249.1"
                     /translation="MKTVSIKHTYWDIAADIYFPDDFNSEKKYPAIISAHPIGSCKEQ
                     TSGSVYGAALAKAGFIVIAFNASFQGSSGGEPRYLEDPTMRVKDFSIVVDYLTTLPYV
                     DAGRIGVLGICGGGGYAINAAMTERRIKAIGTVTGANYGRLMREGFTAFNPIGALEAM
                     AQQRTDEANGAKLRVDDLLPSSPEAALEAGLTEIDLFEATEYYRSPRGCAPNGVNRSL
                     FSHQTVAVGWDAFHLAEVLLTQPLMVVVGDRVGAFGAYRDGCEIIGRAASKHKELVVV
                     EGYSHYDLYDKPEPVKQALDKLIPFYKTHL"
BASE COUNT         1463 a         1274 c         1202 g         1364 t
ORIGIN      
        1 gtgaataatt cattatccag agtgaataat aatgacccgt ctttaattaa ctgctattgg
       61 gagtacgtcg aagtaagtat atacgccggg ataaaccaat atatttttta tggacattca
      121 tttttattca tcggactgta aattccgggg atatcgaact tgcacgacta atctcaaccc
      181 tcaaacagat ttatgaattt tgttcataac ccctgacaaa tcctgccgtc taatcgagct
      241 cttcccttta cgttatgctt ctcatgaacg ataacggaag gataacacca tgcaaaaagt
      301 aaaactgaac aacggtattg aaatgcccct gttgggcttt ggtgtatttc agatgaccga
      361 tgccgccgaa tgcgaaagag cggtcattga cgctattaac agcggttatc gactgattga
      421 caccgccgcc tcttatcaaa atgaaatcca ggtcgggaac gcactgaaac aaagcggtat
      481 cgcccgtaac gaactctttg tcaccacgaa actctggttg caggatacca gttacgaagg
      541 ggccaaagcc cagttcgaac gctctctgaa tcgactgcaa cttgattacg ttgacctgta
      601 cttgattcac cagccatatg gcgatgtcca cggagcctgg cgtgccatgg aagagctgca
      661 acaggccggt aaaattcgcg ctattggcgt cagtaacttc catcctgacc gactggcaga
      721 ccttatcgct tttaataacg tcgttccggc ggtaaaccag gttgaagtta accctttcaa
      781 tcagcagcta caggccgttc cctggatgca aagtcgtggc attcagccag aagcctgggc
      841 accgtttgcg gaagggaaaa atggtctgtt ccagcatcct gttctcacgg caattggcga
      901 gaagtatggc aaaagcgtgg gccaggttgt tctgcgctgg atctaccaac gaggcattgt
      961 ttcactggca aaatcagtgc gaaaagaacg catggaagag aacatcaaca ttctcgattt
     1021 tgaactcagc cctgaagata tgctgcaaat taccgccctg gataccgcaa ccagcgcgtt
     1081 cttctctcac cgcgatcccg caatggtgga atggctgact ggccgcaaac ttgatgttta
     1141 agccgcgata aaagaggtat tcattcaatg caaaaacgtt atctgggtaa atccggactc
     1201 gaagtctccg cccttgggct cggttgcatg ggcttaagcc acggctacgg cccggcgacc
     1261 gatacccgtc aggctatcga acttattcgt gctgcggttg aacgtggtgt caccttcttc
     1321 gataccgccg aagtgtatgg tccgtatctg aatgaagaag tggtcggcga agccttaaaa
     1381 ccgtttcgtg accgcgtggt aattgccact aaattcggtt ttaccttcgg cgatgataat
     1441 aagcagcaga ttttaaacag ccgtccggaa catatccgtg aagccgttga aggatcatta
     1501 cgtcgtctga aaacagatgt tattgacctg ctgtatcaac accgtgttga tccagatgtt
     1561 cctattgaag atgttgcagg aacggtgaaa gacctcatcg cagaaggtaa ggtcaaacat
     1621 ttcggcctgt ctgaagcagg agcacaaacc attcgtcgtg cacatgcggt acaacctgtc
     1681 accgccctgc aaagcgaata ttccatgtgg tggcgtgagc ctgaacagga aattctgccg
     1741 ttgctggagg aactgggaat tggttttgtc cccttcagcc cactaggtaa aggtttcctg
     1801 acaggggcga ttaagccggg aaccactttc ggcaaagatg attaccgcag caccgtaccg
     1861 cgtttcgcag cacaagccat tgaagccaat gaaaaactgg tcaccttgtt aggtgaactg
     1921 gctgcagata aaggggtaac gtctgcacaa atcgcactgg catggctatt agcacaaaag
     1981 ccgtggattg ttcccatccc tggcaccact aaactgaacc ggctggaaga aaacctggcc
     2041 gctgctgaca ttgttctttc gcagaaagat acgcagcaga taaccgaggc gctggaaaca
     2101 attaaaatcg tcggtgaacg ttactcgcct gaacatcagg cacgcgtagg ccgctaatac
     2161 ccaaacgggt ccaggataaa ggacccgtta ttcggtgtag cgaagcgcat cgatcaacag
     2221 cgcaaaagct ggcggatgct gcttgcggct ggggtagtaa agataatacc caggaaaagt
     2281 tggacaccac tcctgtaaca cctgaataag cttgcctgac tttatatact cctgaaccat
     2341 gtcttcaggg acacaagcga tcccaaaccc tgataacgcg gcatcaattc tttctggcaa
     2401 tggactacac gtcagttgcc catcaacctt aacgcgaagc ggtttccctt ctcgctcgaa
     2461 ctcccagtgg taaagcccac cggcagttgg caaacgcatg ttgatgcagc gatgattttg
     2521 tagctcatga ggcgtttcag gcgcagggtt tgcagcaaaa tacgccggag ctcccaccac
     2581 agccatccgc atatctggtc caatcctgac tgcaaccata tctttatcaa cattttcacc
     2641 cagtcgtatc ccggcatcaa aacggccttc aacaatatcg acaaaaccgt tatccaccac
     2701 cagttcgaca ttgatttcgg gatactctct gagaaaaggt tttagcttcg gccagaccag
     2761 acttcgcgcg gcatgttccc cggcagataa ccgaatattc ccggagggcg tgccgttcaa
     2821 ttgaataagt gattccagtt cctgttcaag ctcgtcaata cgcggttcaa ggcaggcaat
     2881 gattctctcc cccgcttctg tgggagccac actgcgggta gtccgtgtca ggaggcggat
     2941 attgagcctt tcctccagag ccttcattgc atggctaagt gcagactgag agacgccgag
     3001 tttgcccgct gctttggtaa aacttcgctc tcttgccacc acaagaaaga tttgcagttc
     3061 gttgaagttt tctttgagca ttggcgattt ccttgtagaa gcatcctctt cacagacact
     3121 catgaagggg ggcatagatg ctattatttt aaccacatta ttagtaacaa tgataatctg
     3181 gctgtatcga aaataattct aaactttcag gagatttatt atgaataaac gtattctcac
     3241 gattgcgcca ttcttcttac cgatattctg acacacatca ttaactttct atttttactc
     3301 ttttctccac cataaaatca ataaaagcac gaactttaga gggcattctc acccgagatg
     3361 aaacatatat ataaaatcca ggaaatgaaa cggcccaatc ctcaagaatc ggctgtaact
     3421 tgcccgcatt gatatgttca gcgattgcaa aatccagatg ttgaatgata cccgttccat
     3481 tcagcgccat tcgtatcatg ctttcgtcat cattagaaat atacttacct gacacctcta
     3541 tttcgaactc ttcattaccc cccacaacat tcgaaaactc ccatgctgag agtgcaccgc
     3601 tacttttatg ccgcaaccga agacaattat ggttactcaa ttcctgagga gtttcaggaa
     3661 taccgtgttc ttttaaataa tctggcgatg ccacagtaac cagtttaata agcggagaaa
     3721 caggaatggc agtcatatgc tcatccagtc cttgctcaag acgtatgccc acatcacagc
     3781 cgtccgcaat aatgttagat aaaccgtcat ccataatgag ttctatcttt gttttggggt
     3841 aacgagtaag aaactcgcca atatgaggct caacaagcat ccttgctgca acacgggagg
     3901 aatttattct caacagtcct gtaggttcaa gttgggtatc accgacatct ttcaacgcat
     3961 catcaatttg ccccaaagcc gacaccagca cttcatacag atgctgtcct tcctcagtaa
     4021 gcgacatatt gcgggttgta cggtatatca gcttggtgtt aagacgttcc tcaagagatt
     4081 ttaaattctg ggacaatgcg gcccgcgtaa tacccatttc agaggctgct ctggaaaaac
     4141 tgccggcacg aacaatcagc gcaaaccagg caagggaagg caaaattgaa ggctctattt
     4201 tcatcattgt aaaccttaac ttaacactgt gatagatatt agaccattga tgataaccaa
     4261 tacaagtcat actattacgc cgttcgcgat atgaacacga atgccagttg cggataatag
     4321 aaatgatatt taaatctgtt taggcaaatc cctggagctt gaaatgaaaa ctgtttcaat
     4381 aaaacacact tactgggata tagctgctga tatctatttc cctgacgatt ttaatagtga
     4441 aaaaaagtat cctgccatta tcagtgccca tccaattgga agctgcaaag aacagacatc
     4501 gggtagtgtg tatggtgccg ccctggcaaa agctggcttt atcgtcattg cttttaatgc
     4561 cagttttcag ggaagcagcg gtggagaacc gcgttatctg gaagatccaa caatgcgagt
     4621 aaaagacttc agcattgtcg ttgattacct taccacctta ccttacgttg atgccgggcg
     4681 tattggtgta ctgggtattt gtggtggagg tggatatgcc attaatgccg caatgacaga
     4741 acgtcggatt aaagccattg gtactgtcac aggtgcaaac tacgggcgtc ttatgcgtga
     4801 gggatttaca gcgtttaatc ctatcggagc actcgaagca atggcgcaac aaagaacaga
     4861 cgaagctaac ggcgcaaaac ttcgcgtaga tgatttgctt ccttcttctc cggaagcagc
     4921 tcttgaagcg ggattaacag aaatagacct ttttgaagca acagaatatt atcgttcgcc
     4981 acgaggctgt gcgcctaatg gggtaaatcg ttcgctattt tcacatcaga ctgttgccgt
     5041 gggctgggat gcttttcatc ttgcagaagt cctgttaact caaccactaa tggttgtagt
     5101 aggcgataga gtgggcgctt ttggtgccta tcgtgacggc tgcgaaatta ttggtcgtgc
     5161 agcctcaaaa cataaagagt tggtcgtggt tgaaggttat tcacattacg acctgtatga
     5221 taagccagaa cctgtgaaac aggcgctcga taaattaatt cctttttaca aaacacattt
     5281 gtaataacct tgcagggaga ttc
//
LOCUS       DAFGPF010000206         5221 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFGPF010000206 DAFGPF010000000
VERSION     DAFGPF010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5221
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.207"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1785
                     /locus_tag="LSX49_004983"
     CDS             <1..1785
                     /locus_tag="LSX49_004983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HBL7171250.1"
                     /translation="YRKTLVAGTVAITLGLSASGVMAAGFKPAPPAGQLGAIIVDPYG
                     NAPLTALVDLDSHVISDVKVTVHGKGEKGVDISYKVGNESLKTYDGVPIFGLYQKFAN
                     KVTVEWKENGKAMKDDYVVQTSAIVNNYMDNRSISDLQQTKVVKVAPGFEDRLYLVNT
                     HTFTAQGSDLHWHGEKDKNAGILDAGPATGALPFDIAPFTFIVDTEGEYRWWLDQNTF
                     YDGRDRNINKRGYLMGIRETPRGTFTAVQGQHWYEFDMMGQVLEDHKLPRGFADATHE
                     SIETPNGTVLLRVGKSNYRRDDGVHVTTIRDHILEVDKSGRVVDVWDLTKILDPKRDA
                     LLGALDAGAVCVNVDLAHAGQQAKLEPDTPFGDALGVGPGRNWAHVNSIAYDAKDDSI
                     ILSSRHQGVVKIGRDKQVKWILAPSKGWEKPLASKLLKPVDANGKPITCNENGLCENS
                     DFDFTYTQHTAWISSKGTLTIFDNGDGRHLEQPALPTMKYSRFVEYKIDEKKGTVQQV
                     WEYGKERGYDFYSPITSIIEYQADRNTMFGFGGSIHLFDVGQPTIGKLNEIDYKTKEV
                     KVEIDVLSDKPNQTHYRALLVRPQQMFK"
     gene            1803..2471
                     /locus_tag="LSX49_004984"
     CDS             1803..2471
                     /locus_tag="LSX49_004984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HBL7171251.1"
                     /translation="MSKLGISSLFKTILLTAALAVSFTASAFTEGTDYMVLEKPIPNA
                     DKTLIKVFSYACPFCYKYDKAVTGPVSEKVKDIVAFTPFHLETKGEYGKQASEVFAVL
                     INKDKAAGISLFDANSQFKKAKFAYYAAYHDKKERWSDGKDPAAFIKTGLDAAGMSQA
                     DFEAALKEPAVQETLEKWKASYDVAKIQGVPAYVVNGKYLIYTKSIKSIDAMADLIRE
                     LASK"
     gene            2486..3157
                     /gene="dsbI"
                     /locus_tag="LSX49_004985"
     CDS             2486..3157
                     /gene="dsbI"
                     /locus_tag="LSX49_004985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide oxidoreductase DsbI"
                     /protein_id="HBL7171252.1"
                     /translation="MGIKGMWKDLRTSPVDTLVRWQEQRLLWLLMAVAMGTLIILAHS
                     FFQIYLYMAPCEQCVYIRYAMFVMVIGGLVAAINPKNIILKLIGCVMAFYGSILGLKF
                     SLKLNDIHHAVHNPDPDSLFGVQGCSTDPTFPFNLPLAQWAPNWFKPTGDCGYDAPIV
                     PDGVTLSSTQQWFVEMYQQSEGWYLLPPWHFMNMAQACMLAFGMCLVLLVIMSGAWAL
                     KIIRG"
     gene            complement(3203..3991)
                     /gene="ygiD"
                     /locus_tag="LSX49_004986"
     CDS             complement(3203..3991)
                     /gene="ygiD"
                     /locus_tag="LSX49_004986"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HBL7171253.1"
                     /translation="MSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVV
                     VSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPALAQHLVELLAPVPVT
                     LDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIML
                     VASGNVVHNLRTVKWHGDSSPYPWAMSFNEYVKANLTWQGPVEQHPLVNYLDHEGGAL
                     SNPTPEHYLPLLYVLGAWDGQEPITIPVDGIEMGSLSMLSVQIG"
     gene            4134..4907
                     /gene="zupT"
                     /locus_tag="LSX49_004987"
     CDS             4134..4907
                     /gene="zupT"
                     /locus_tag="LSX49_004987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBL7171254.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            complement(4969..5139)
                     /locus_tag="LSX49_004988"
     CDS             complement(4969..5139)
                     /locus_tag="LSX49_004988"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171255.1"
                     /translation="MFIAWYWIVLIVLLAGGYFLHLKRYCKAFRHDRDALLAARSKLD
                     KRSDKEVFEKHQ"
BASE COUNT         1357 a         1282 c         1271 g         1311 t
ORIGIN      
        1 tatagaaaaa cactcgtagc cggaactgtg gcgataaccc tgggtttgtc agcatcgggg
       61 gtgatggctg cgggttttaa accagcaccg cctgccgggc agcttggggc gattatcgtc
      121 gatccctacg gtaatgcgcc cttaaccgcg ctggttgatt tagacagcca tgttatttct
      181 gacgtcaaag ttaccgtcca cgggaagggc gaaaaaggcg ttgacatcag ctataaagtg
      241 ggcaacgagt cactgaaaac ttacgatggt gtaccgattt ttggtcttta ccagaagttt
      301 gcgaacaaag tgaccgttga gtggaaagaa aacggtaagg ccatgaaaga tgattacgtg
      361 gtgcagactt ccgccatcgt caacaattac atggataacc gctccatctc cgacctacag
      421 caaaccaaag tcgttaaagt cgcgccaggt tttgaagatc gcctctatct ggttaatacc
      481 cacaccttta ccgcccaagg ttccgatctc cactggcatg gtgagaaaga taaaaatgcc
      541 ggtatccttg atgcgggtcc ggcaactggc gcactccctt ttgatatcgc gccattcacc
      601 tttatcgtcg atacggaagg cgaataccgc tggtggttgg atcaaaacac cttctacgat
      661 ggtcgtgacc gcaacattaa caaacgtggt tatctgatgg gtatccgtga aacgccacgc
      721 ggcaccttta ccgctgtaca aggtcagcac tggtacgagt tcgacatgat ggggcaggtg
      781 ctcgaagatc acaaactacc gcgcggattt gctgacgcca ctcatgagtc cattgagacg
      841 ccaaatggca cggtactgtt gcgcgtaggt aagagtaact atcgtcgcga tgacggcgta
      901 cacgtcacca ccattcgtga ccatatcctc gaagtcgata aatctggtcg cgttgtcgat
      961 gtatgggatc tgaccaagat cctcgatccg aaacgcgatg cactgctcgg cgcgctggat
     1021 gcaggtgcag tttgcgttaa cgttgacctt gcccatgcag gacaacaggc aaaactggaa
     1081 ccagatacac cgttcggcga cgcgctgggt gtagggccag gccgcaactg ggcgcacgtg
     1141 aactctatcg cctatgacgc aaaagatgac tctatcatcc tctcctctcg ccaccagggt
     1201 gttgtgaaga ttggtcgtga taagcaagtg aaatggatcc ttgcgccctc taaaggttgg
     1261 gaaaaaccgc tggccagcaa gctgctgaaa ccggttgatg ctaacggtaa gccaattacc
     1321 tgtaacgaaa atggcctgtg cgaaaactca gacttcgact ttacctacac ccagcatacc
     1381 gcctggattt ccagcaaagg aacgctcacc atttttgata atggcgatgg gcgtcatctg
     1441 gaacaacctg ccttaccaac catgaaatac tcccgctttg tggaatataa gattgatgag
     1501 aagaaaggca ccgttcagca agtgtgggaa tacggtaaag aacgtggcta cgatttctat
     1561 agcccgatta cctccatcat tgaatatcaa gccgaccgta acaccatgtt tggcttcggt
     1621 ggttctattc atttgttcga tgtcgggcag ccaaccatcg gtaagttgaa cgaaatcgat
     1681 tacaaaacca aagaagtgaa agtggaaatc gacgtgctgt cagataaacc caatcagact
     1741 cactatcgtg cactgttagt ccgtccacaa cagatgttca aataattaag aagggaataa
     1801 aaatgtcgaa attagggatc tcatcactat ttaaaaccat actgcttacc gcagctttgg
     1861 ctgtttcatt taccgcttct gcatttaccg aaggcacgga ttacatggtt ctggaaaaac
     1921 ctattccgaa tgccgacaaa acgctgatta aggtatttag ctacgcctgc ccgttctgtt
     1981 acaagtacga caaagcggtt accggtccgg tatcggaaaa agtgaaagat atcgttgctt
     2041 tcacgccgtt ccatctggaa accaaaggtg aatacggcaa acaagcaagc gaagtctttg
     2101 cggtcttgat caataaagat aaagcagcag gcatttcctt atttgatgct aactctcagt
     2161 ttaagaaagc caagtttgcc tactacgcgg cttatcacga caaaaaagaa cgctggtctg
     2221 acggtaaaga tcccgctgcc tttatcaaaa ctggtctgga tgccgcaggt atgagtcagg
     2281 cggattttga agcggcactg aaagaaccag cagttcaaga aacactggaa aaatggaaag
     2341 cctcttatga tgtcgccaaa atccaggggg ttccagccta tgtcgttaat ggtaagtact
     2401 tgatctacac caagagcatc aaatccatcg acgcgatggc agaccttatc cgtgagttag
     2461 caagcaaata acagggaaac aggctatggg tattaaggga atgtggaaag atcttcgcac
     2521 atcaccagtt gacacactgg tcagatggca ggagcaacgc ttgttgtggt tgttaatggc
     2581 cgttgcgatg ggcacgttaa ttatcctggc gcactctttc ttccagatct atctctacat
     2641 ggcaccctgt gagcaatgtg tatacattcg ctacgccatg tttgtgatgg tgattggagg
     2701 attggttgca gcgatcaatc caaagaacat catcctcaag ctaattggct gcgtgatggc
     2761 attttacggc agcattttgg gactgaagtt ttcgctcaaa ctgaacgata tccaccatgc
     2821 agtacataat ccggatcccg attcactgtt tggcgtacag ggttgctcta ccgatcccac
     2881 ttttcccttt aacctgccgc tggcacagtg ggcaccaaat tggttcaagc ctaccgggga
     2941 ttgtggctat gacgcaccaa tcgttcctga tggcgtcaca ctgagcagca cgcaacagtg
     3001 gtttgtggaa atgtatcagc aatctgaagg ctggtatctg ctaccaccat ggcattttat
     3061 gaatatggct caggcttgta tgctggcttt tggtatgtgt ctggtgctgc tggtcattat
     3121 gagtggcgca tgggcgctta aaatcatcag aggctaactc agcaacaccc gaagccagtc
     3181 attctggctt cgggttcttt tattaaccta tctgcaccga cagcatactt aaactgccca
     3241 tttctatacc atcgaccgga atggtaattg gctcctgccc atcccacgcc cctaagacat
     3301 acaacaacgg cagatagtgc tctggcgttg ggttcgataa cgcgccacct tcatggtcga
     3361 gataattcac cagaggatgt tgttccaccg gcccttgcca cgtcagattc gctttcacat
     3421 actcattaaa cgacatcgcc cacggatacg gtgaactatc accgtgccac ttcactgtac
     3481 gcaggttatg caccacgttg ccactggcga ccaacattat cccttcatca cgcagcgccg
     3541 cgagtttgcg ccccatttcg aaatgccagg cggcaggttt gctactgtcg atactcaact
     3601 gcaccatcgg gatatcggcg tcaggataca tcttaatcag tacgccccac gagccgtggt
     3661 cgaagcccca ggcttcttta tccagcgtca cagggaccgg cgctaacagc tcaaccagat
     3721 gctgtgccag cgcaggtgaa cccggagcag gataatgcgt atcgtacagc gcctgcggga
     3781 agccaccaaa gtcatgaatc gtgggcggcg tctccatcgc ggtcactcct gttccacggg
     3841 taaaccaatg agccgaaacc accacaatcg cttgcgggcg tggcaatgtc atccccaact
     3901 tctgccagct gcgggtatac aaattatctt ccagcacgtt catcggacta ccgtgaccta
     3961 aaaacaatgc tggcatacgt gttgaagaca tgatgatatc cttaactaaa ggtgtcattt
     4021 tgatatcctc acaatacgct tgttcggcgg agtaagaacc cggataacaa tgatgatgat
     4081 catcagttat tttgacgatc tgcctgaagg tgaagattta taaggagttg tcgatgtcag
     4141 tacctctcat tctgaccata ctggcggggg cagccacgtt tattggcgcg tttctcggcg
     4201 ttctcgggca aaaaccctcg aaccgcttac tggcgttttc gctaggattt gcggcgggga
     4261 tcatgttgct catctcatta atggaaatgc ttcctgccgc attagccgcc gaaggaatgt
     4321 cacctgtgtt gggttatgga atgtttatct tcggtctgct tggctatttt ggtctggacc
     4381 gcatgttgcc acatgcgcat ccgcaggatt taatgcaaaa atcggtgcag ccgttgccaa
     4441 aatcgatcaa gcgcacagcc attctgctca ctctcggtat cagtctgcat aacttcccgg
     4501 aagggattgc cacctttgtc acggcgagca gcaacctgga gctgggattt ggtatcgccc
     4561 tggccgtagc gttgcacaat attcctgaag gtctggcggt tgcaggcccg gtttacgcgg
     4621 caacggggtc aaaacgtacc gcaattctgt gggcggggat ttccggactg gctgaaattc
     4681 tcggtggtgt gctggcatgg ttaattcttg gcagcatgat ttctccggtg gtcatggcgg
     4741 caatcatggc ggcggttgcc ggtattatgg tggcgctctc ggttgatgaa ttaatgccgc
     4801 tcgccaaaga gattgacccc aataataacc ccagttatgg cgtgctatgt ggaatgtcag
     4861 tgatgggatt cagtttagtg ctgctacaaa cggcaggaat tggttaaaga tgataatgac
     4921 agatgttgcc cattgctaaa ggcaacatct gtatcgttat taaaggtatt attgatgctt
     4981 ttcaaacact tctttatcgg agcgtttatc taatttactt cgggcagcta acagcgcatc
     5041 tctgtcatgg cgaaaagctt tacagtaacg tttaagatga agaaaatagc caccagctag
     5101 tagaacaatt aatacaatcc agtaccaggc aataaacatc cttttcacct tcaaaattta
     5161 acattactaa acatttagcg ttaaaatttc acatatccaa cgttgaatat attcatatac
     5221 t
//
LOCUS       DAFGPF010000207         5207 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFGPF010000207 DAFGPF010000000
VERSION     DAFGPF010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.208"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            36..380
                     /locus_tag="LSX49_004989"
     CDS             36..380
                     /locus_tag="LSX49_004989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001382850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171256.1"
                     /translation="MLESHKQKRTEKIDVAVRLVGLKAYDLHEGIPDRPKRKVKDGIN
                     EDIKADTSLRLSKTNISDTSLNRYRRTVKEIINNEIDVFLLEQKKKNKRFPYSEDRDV
                     IRPLWGKCLTGQ"
     gene            complement(467..1063)
                     /locus_tag="LSX49_004990"
     CDS             complement(467..1063)
                     /locus_tag="LSX49_004990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171257.1"
                     /translation="MAVIPMSYSPATVARRFSILDGVTIQGVLYQIIWDPKTPFAAVI
                     EAAPSVIDGDIRHKVVATLELQRRSQLEGVFVRKFWEEQDVAQIEGIVVDGAVRDVSL
                     ATFVYETIATKAGVILLSDNEQYEGGKALWQHIARRSTNLKVFILDTDSARYYPFDGD
                     RICYDGESIPESEIWSEHPDRNKHGVVLVAESVNGKAA"
     gene            complement(1374..1449)
                     /locus_tag="LSX49_004991"
     tRNA            complement(1374..1449)
                     /locus_tag="LSX49_004991"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1414..1416),aa:Thr,seq:cgt)
     gene            complement(1564..2817)
                     /gene="proA"
                     /locus_tag="LSX49_004992"
     CDS             complement(1564..2817)
                     /gene="proA"
                     /locus_tag="LSX49_004992"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBL7171258.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILN
                     ANAQDVADARANGLSEAMLDRLTLTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALNSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADTAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            complement(2829..3932)
                     /gene="proB"
                     /locus_tag="LSX49_004993"
     CDS             complement(2829..3932)
                     /gene="proB"
                     /locus_tag="LSX49_004993"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBL7171259.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            4221..>5207
                     /gene="phoE"
                     /locus_tag="LSX49_004994"
     CDS             4221..>5207
                     /gene="phoE"
                     /locus_tag="LSX49_004994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HBL7171260.1"
                     /translation="MKKSTLALVVMGIVASVSVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPISGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYVDVGATYYFNKNMSAFVDYKINQL"
BASE COUNT         1397 a         1310 c         1219 g         1281 t
ORIGIN      
        1 aaacatttca aaaatggtat gaaaaaaata aagttttgtt agaaagtcat aaacaaaaac
       61 gaacagagaa gattgacgtt gccgtacgac ttgtagggct gaaagcctat gatctgcatg
      121 aagggattcc ggataggcca aaacgaaaag ttaaagatgg cataaatgaa gacatcaaag
      181 ccgataccag tttacgcctg tcaaagacaa atataagtga tacgtcgcta aaccgttatc
      241 gccgcactgt taaggagatt atcaataacg aaatcgacgt attcctgttg gaacagaaga
      301 aaaaaaataa aagatttccc tacagtgaag atagagatgt gattcgacct ttatggggaa
      361 aatgcctgac cggacaataa ctccctgagg ggataacagc ccggttatcc cctgttcgtt
      421 atgcctcggt ataccggagt tccagggaca cgagacaatc ggcaaattat gcggcttttc
      481 cattaacaga ttcggctaca agaacaacac cgtgtttgtt tcgatcagga tgttcactcc
      541 agatttctga ttcaggaata ctttccccat catagcagat ccgatcacca tcaaacggat
      601 aataccgtgc ggaatctgta tctaagataa acaccttaag attcgttgaa cgacgcgcta
      661 tatgctgcca gagggcttta cctccttcat attgctcgtt atcacttaat agtataacgc
      721 ctgcttttgt ggctattgtt tcataaacaa acgtagcaag gctaacatca cgtacagcgc
      781 catcgacaac aatcccttca atctgagcaa cgtcctgttc ttcccagaat ttccggacaa
      841 acaccccttc aagctgtgaa cgacgctgaa gctccagagt ggcaacaacc ttatggcgaa
      901 tatcaccatc aataacagaa ggtgcagctt cgattaccgc agcgaacgga gtctttggat
      961 cccagatgat ctggtaaagc acaccctgaa tagttactcc atccagtatc gaaaaacgac
     1021 gagctacagt agcaggggag taagacattg gaatgacagc cattttatgg cctaaaattt
     1081 gaaaacatta gtatcaatac tgacctcatc agtctgagca tatattgata aagtttttat
     1141 gtttacactc aataaatacc ttgccaaaca actaatagcg atgtctacat tgccattcga
     1201 catgcttaca atttttgtca acaagaaagt gaatttatat caacggtaag aagtaaacac
     1261 gaggacacca aaaccaaatg tacacacttt tgtgctttgt gtcccctgtg tgtacccaaa
     1321 tgacaaactg caagaaaatc taggcacaca cttatctaac ttattgattt aaatggtgcc
     1381 gataatagga gtcgaaccta cgaccttcgc attacgaatg cgctgctcta ccaactgagc
     1441 tatatcggcc ctgaaaggac atgttcacga acgtgaatca cggtggacaa ggttaaaact
     1501 aaccgggcga tgcgtcaatg gccttgtgaa tcaaatggct acttttgcat cacccggttt
     1561 tatttacgca cgaatggtgt aatcaccaat gccgatccac ttgtaagtgg tcagtgcttc
     1621 cagccccatt gggccgcgcg cgtggagttt ttgtgtgctt accgccactt ccgcccccag
     1681 tccaaactgg ccgccgtcgg taaaacgcgt agaggcgtta acgtaaacag cggaggaatc
     1741 cacttcgtta acaaaacgct gggcgttgcg catatcgcgg gtcaggatcg catcggagtg
     1801 ttgcgtgccg tgttcacgaa tatgggcaat ggcgtcatcc agatcgctaa cgattttgac
     1861 gttcaaatct aatgacagaa actcatcgtc atactcttcg gctttaacag ccaccacctt
     1921 cgcggggcct gcctgcaact gcgccagcgc ggctgtatca gcgtgtaacg tcacgccgct
     1981 ttccgccatt tgtttgctta atgcgggcag gaagctatca gcgatgtttt tattcaccag
     2041 caacgtttct accgtattac acgtgctcgg acgctgagtt ttcgcgttga caattacttt
     2101 cagggcttca gcgatctctg cgctttcatc aacgtaaata tggcatacgc ctataccgcc
     2161 tgtgatcacc gggattgtcg actgctcgcg gcacagttta tgcaaaccag ccccgccgcg
     2221 cgggatcagc atgtcgatgt atttatccat acgcagcatt tcactgacca gcgcacggtc
     2281 aggattatca atcgcctgca cggcacccgc cggtaagcca caagagttca gggcgtcctg
     2341 aatcaccgcc accgttgcag cgttagtgcg acacgtttct ttgccgccgc gcaggatcac
     2401 tgcgttacct gttttcaggc acagcgaagc gacatcaacc gtcacgttcg ggcgcgcttc
     2461 ataaatcacg ccaataaccc ccagcggtac gcgacgacgc tcaagacgca ggccgctgtc
     2521 cagtacgccg ccatcgatta cctgccccac cggatcggcg aggttgcaca cctggcgcac
     2581 atcatcggca atgcctttca gccgtgcggg cgtcagtgtc agacggtcaa gcatcgcttc
     2641 gctaaggcca ttggcacgcg cgtctgcaac atcctgcgcg ttagcgttga ggatactttc
     2701 gctttgtgct tccagttcat cggcgatttt ttccagcaca cgattttttt cgcggctgga
     2761 gagttgcgct aatttatacg aggcttgctt cgcggcaatg cccatttgtt ccagcatcgg
     2821 ccagctcctt aacgggtaat catgtcatca cggtgaacgg caaccgggcc gtattcatat
     2881 cccagtattg catcaatttc ttgcgagtgg tgtccggcaa tacggcgtaa tgcatcgctg
     2941 ttgtaacgac tgacgccgtg ggcgatatcg cgaccttcga ggttgcaaat acggatgact
     3001 tcaccacgcg agaaattgcc agtcacgctt ttaatgcctt tcggcaacag ggagctgccg
     3061 cgttccagaa tggcggcagt tgccccttca tctaccgtga tttcacccgc aggcggcgca
     3121 ccgaaaatcc agcgtttacg gttttcaagc ggagtcgcct gggcatggaa cagcgtaccg
     3181 acggaaatgc cttccatcac atcaccaata acgcccggct tgctgcccgc ggcaataatg
     3241 gtgtcgatac ccgcacggca agccacgtca gcggcctgca atttggtgct cataccgcca
     3301 gttccgaggc ctgaaacgct atcaccggca atcgcgcgca gtgcgtcatc aatgccgtac
     3361 acatctttaa tcagttctgc ctgcggattg ctgcgcgggt cagcggtata caaacctttt
     3421 tgatcggtca gcagcaacag tttatcggca cccgccagaa tcgccgccag cgcagaaagg
     3481 ttatcgttat caccgacctt aatctctgcc gtagcgacag catcgttctc attaattacc
     3541 ggaacgatat tgttatcgag caacgcacgc agggtatcgc gggcgttcag gaagcgttca
     3601 cgatcttcca tatcagcacg ggtcagcaac atctgcccga catgaatgcc gtaaattgaa
     3661 aacagctgtt cccacagttg aatcagtcga ctctgcccta ccgccgccag cagctgtttt
     3721 gaagcgatag tcgctggcaa ttccgggtac cccaggtgct cacgtccggc ggcaatcgca
     3781 cccgacgtca caataacaat ccgatgcccg gcggcatgta actgcgcgca ctggcgaaca
     3841 agttcaacga tatgggcacg gttcaggcgg cgcgatccgc ctgttagcac actggtgccg
     3901 agttttacca ccagcgtctg gctgtcactc atgattctct gccattcaat tttaggaaaa
     3961 aatgatatca aacgaacgtt ttagcaggac tgtcgtcggt tgccaaccat ctgcgagcaa
     4021 agcatggcgt tttgttgcgc gggatcagca agcgtagcgg cagttgttta cgcttttatt
     4081 acagatttaa taaattacca cattttaaga atattattaa tctgtaatat atctttaaca
     4141 atctcaggtt aaaaactttc ctgttttcaa cgggactctc ccgctgaata ttcgcgcgtt
     4201 aattaaaatc aggaatgaaa atgaaaaaga gcactctggc attagtggtg atgggcattg
     4261 tggcatctgt atccgtacag gccgcagaaa tatataacaa agacggtaat aaactggatg
     4321 tctatggcaa agttaaagcc atgcattata tgagtgataa tgacagtaaa gatggcgacc
     4381 agagttatat ccgttttggt tttaaaggcg aaacacaaat taacgatcaa ctgactggtt
     4441 atggtcgttg ggaagctgag tttgccggta ataaagcgga gagtgatact gcacagcaaa
     4501 aaacgcgtct cgcttttgcc gggttgaaat ataaagattt gggttctttc gattatggtc
     4561 gtaacctggg cgcgttgtat gacgtggaag cctggaccga tatgttcccg gaatttggtg
     4621 gcgactcctc ggcgcagacc gacaacttta tgaccaaacg cgccagcggt ctggcgacgt
     4681 atcggaacac cgacttcttc ggcgttatcg atggcctgaa cttaaccctg caatatcaag
     4741 ggaaaaacga aaaccgcgac gttaaaaagc aaaacggcga tggcttcggc acgtcattga
     4801 catatgactt tggtggcagc gatttcgcca tcagtggagc ctataccaac tctgatcgca
     4861 ccaacgagca gaacctgcaa agccgtggca caggcaagcg tgcagaagca tgggcaacag
     4921 gtctgaaata cgatgccaat aatatttatc tggcaacttt ctattctgaa acacgtaaaa
     4981 tgacgccaat ctctggcggc tttgccaata agacgcagaa ctttgaagcg gtcgctcaat
     5041 accagtttga ctttggtctg cgtccatcgc tgggttatgt cttatcgaaa gggaaagata
     5101 ttgagggcat cggtgatgaa gatctggtca attatgtcga tgttggtgct acgtattatt
     5161 tcaacaaaaa tatgtcagcg tttgttgatt ataaaatcaa ccaactg
//
LOCUS       DAFGPF010000208         5119 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFGPF010000208 DAFGPF010000000
VERSION     DAFGPF010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5119
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.209"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..773)
                     /locus_tag="LSX49_004995"
     CDS             complement(<1..773)
                     /locus_tag="LSX49_004995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HBL7171261.1"
                     /translation="MQRKTLLSACIALALSGQGWAADITEIETTTGEKKNTNVTCPAD
                     PGKLSPEELKRLPSECSPVVEQNLMPWLATGAATALITALAIVELNDDDDHHHRNNSP
                     LPPTPPDDNSDDTPVPPTPGGDEIIPDDGSDDTPTPPKPISFNNDVILDKTAKTLTIR
                     DSVFTYTENADGTISLQDSNGRKATINIWQIDEANNTVALDGVSADGATKWQYNHNGE
                     LVITGDNATVNNNGKTIVDGKDSTGTEIAGNNGKVIQDG"
     gene            complement(1101..1429)
                     /locus_tag="LSX49_004996"
                     /pseudo
     CDS             complement(1101..1429)
                     /locus_tag="LSX49_004996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="involved in the synthesis of a cofactor required
                     for carnitine dehydratase and carnitine racemase
                     activities; frameshifted; incomplete; partial in the
                     middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
     gene            1437..1679
                     /locus_tag="LSX49_004997"
                     /pseudo
     CDS             1437..1679
                     /locus_tag="LSX49_004997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067515.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(1851..2177)
                     /locus_tag="LSX49_004998"
     CDS             complement(1851..2177)
                     /locus_tag="LSX49_004998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HBL7171262.1"
                     /translation="MKRTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVAL
                     KTDAETEKLVTDINAERKASYQQLAKQNNVSVDDIAKLAGQKLVERAKPGEYVQGING
                     KWVRKF"
     gene            complement(2185..2370)
                     /locus_tag="LSX49_004999"
     CDS             complement(2185..2370)
                     /locus_tag="LSX49_004999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HBL7171263.1"
                     /translation="MKILLAALTSSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            complement(2367..5006)
                     /locus_tag="LSX49_005000"
     CDS             complement(2367..5006)
                     /locus_tag="LSX49_005000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HBL7171264.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKL
                     PQTEQSPAAPKTLAQWQAMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFTMPLVPDGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTG
                     EAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPVVWGRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLAPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEDKQ"
BASE COUNT         1304 a         1299 c         1135 g         1381 t
ORIGIN      
        1 ataccgtcct gaataacttt cccgttatta ccggcgatct ccgtgccagt ggaatcttta
       61 ccatcaacga tggttttgcc attgttgttt actgtggcat tatcacccgt aataacaagc
      121 tcaccgttat gattatattg ccacttcgtt gcgccatctg cgctcacccc gtcaagggca
      181 accgtgttat tcgcttcatc aatttgccaa atattaatag ttgccttacg gccattgcta
      241 tcttgtagag aaatagtccc gtcagcattc tcggtataag taaaaactga atcgcgaata
      301 gttaacgttt ttgctgtttt atcgaggata acgtcattat taaacgaaat tggtttggga
      361 ggcgtcgggg tatcatccga accgtcgtct ggtattatct catctccgcc aggagttggg
      421 ggaactggag tgtcgtctga attatcatca ggtggagttg gtggaagtgg agaattattg
      481 cgatgatgat gatcatcatc gtcgtttagt tccactatgg ctaaggctgt gattaacgca
      541 gtagcagcac ctgtggcaag ccatggcatc aggttctgtt cgactacagg ggagcattca
      601 gagggtaagc gtttaagctc ttctggactg agttttccag ggtctgccgg acaagtcaca
      661 ttggtatttt tcttttcacc tgtggtggtt tctatctctg tgatatctgc cgcccagccc
      721 tgaccactca gagccaatgc aatacaggct gacaatagag ttttcctttg cataataaat
      781 ccttctggcg aatataaaga aggtcggatg ccttaaccca accaattaat caatcaatta
      841 aaacatagag gacattcaat attgccagta gattggcacc taatcaaaca tattctctga
      901 caatctgtaa ttataatttg agtgaatgaa tacacctgca taatatacaa cttgcgtata
      961 ttatatgaat tatagattta aatggcatca gataagcatt catttgataa aaaacggtac
     1021 aaatcaatac tcaaataaat aaatcagagc agaagcataa ttctgcttta taattaaagg
     1081 gaaaaataat tatataactg ttactgtttc ggtcgcagat tctcatcaaa caccaggcgt
     1141 ttcctgccag gttcaacttc ccgcaatggc tcgacttgat gcaacgtctg cttacaacga
     1201 gtcaccagca cctgatgccc tgctttctca atgccagctc ctgctcgctg agttcacgaa
     1261 tcgctttcgc cgggctgctg acaatcaagt aattagtcgg catttctgct ttggctttca
     1321 caaatgcgga aacaccaaca atactgttct caccaatcac cacaccgtcc atcactaccg
     1381 cgttaattcc cactaatgta tggcggtggt taatgcagcc gtgaagaata gtcggagata
     1441 caggtatgtc agtacgtagt ttgtaccgaa tgtttgccga taaaggtttg gtggtcgcgc
     1501 aatatattcg taaccgtcgt ctcgattttt gtgcagatgc gattcgccat gccgcagatg
     1561 atgaaaaact ggcaggcatt ggctttcatt ggggattttc cgaccagagt catttttcaa
     1621 cggtatttaa acaacgcttt gggatgacgc caggcgagaa tcggcgtaaa ttccgctaac
     1681 taattcgcgt tgcatgtaca gcaacgcgaa ttagttaaaa cagatatttg actatgcatt
     1741 tttcagggcg aaaggcaatt tgacaggcgt ttttgaataa tcatcttgtt tccggaaaat
     1801 agattaatcg ccttctcctg tagcgttatc ccgatattgc ggctttacta ttaaaatttt
     1861 cgcacccatt taccgtttat cccttgtaca tattccccgg gtttggcccg ttctacgagc
     1921 ttttgcccgg cgagtttcgc gatatcatct accgacacat tattttgctt tgccagttgt
     1981 tgatagctcg ctttacgttc ggcattaatg tcggttacta atttctcagt ttcagcatct
     2041 gttttcagcg caaccagata accataaaat gtttcgccta cccgcccctg agttctggct
     2101 tcatccagag tcaatgccat tacattgctg cttaccaagc caacaagaaa tgcacaaaga
     2161 agtaatgttc ttttcatcat cacctcaaaa aagatcgcta cgggtctcaa gcagctcttc
     2221 gacatctttg tctgccttga tgatgatctc atgctcaatt ttaacgttca tattgatagt
     2281 gatcggttcc ttaggtgcag cgacttcaat acgaggcgta cagccaacca gcataaaaga
     2341 tgacgtcaac gcagccagta aaattttcat tgtttatcct cacactcttt tccttgcgga
     2401 cagtcatttc ccggcagacg cgcgttctgc tccagccatg cctggagatt atcgccaaag
     2461 cgtaaactgc gccacagcgt aaaaatattc tcttcatgat ggtaattaag atttaccgta
     2521 ccgcttttac catcaacgcg actggtacct gtaatattgg cctgcatggt taataaaccg
     2581 agattatcta aattaatttt tgtcgatgaa cggctaattt ccatatagcg caaccagtta
     2641 attgctgaac ccgcggtcat attgtctttc accaccgcat ctgcggtgtc tttatccagc
     2701 cgcaaggtca ttggtccgct atttgccagc cagccgtctt tcactatcca tttttcattg
     2761 tttaaccata acggcagtgc accactaaat gccccggaca tggcgaattg tttcggatta
     2821 acggcgctaa ccagttcgct ggatgagaga ttattcagtc gcaacagtgc cgggtcatgt
     2881 tgcggcatac gtaattgttt catcagcacg ttaccgccta acacatcgac actaacatca
     2941 gtcaacagca atggttcttc ttcagtccac ggataacgcc cttgcaaatc agccgtaata
     3001 tttttcgctg tcaccagatt aatcacttcg gcaattcgca acgtaacggg gccgcgagtc
     3061 cccagatgcc aggctccatc ggcaaaacgg aaaggcagga caaaatcgac accgttaacc
     3121 tgattatctg gcatccaggc actaccgcct ttcaatacgc cgtgcccccc cgcgcggaat
     3181 ccttgttcgg gcgctgctga aaatgcgacc tgagcataca gttcaccatc gcgtaagttc
     3241 atcttccagt cgggtggcgc caacggctgg aatacagtca gtgattgttt aggccaccag
     3301 gcgttaccgc gcagacgaat accgtcccag cgaccattta cccgaaccgg gccaatctca
     3361 ccagcatgta aatcgccttt aaagaggaaa tacgtcggat cgcgcccatc gacactaaat
     3421 tttaaggttg atggcggtaa cacactgccg ccagtgaaca gcgtttgccc ggcgtccagt
     3481 gacagagcgc cgctgaagga gggatgctgt gcgtcacgtc cccagacgac gggcttgtcg
     3541 agaattaatc gcggcttttc taccgtcatc gtaccgtatt gtaactggtc gaaaccggtg
     3601 gagagatcgg tcagcgtaat cgtgctgtca tgccactcac cttttcctgc gacatcccag
     3661 gtggcattca tcggtgtaaa actccctttt ccccagtagc gccactgcca gcggccagcg
     3721 tcagggagaa aatcattcgc cagcccatcc atatgcagca cgaaatcgcc cagttcattt
     3781 tcatgcgcct gcaaaatggc ctgcaaacgt ccgtcaacac cacgttgggt gacttttaca
     3841 cccgctaaag gccagcggat ttcatcgatg tccagcgaat caatgactct tccctttgaa
     3901 cgaagtaacg cgccaggctc aaaggtcagc gttgggtcag acagacttcc acttagctgc
     3961 gcaggtaaac gggcatataa aatgaggtcc gcctgtttcg cttcaccggt cagctgcaga
     4021 ggcagctggc tgttatccat gcttaatttt cctgggccaa aatttaacac cgcgttgcct
     4081 ttacccgctt gcccctgggt cagcacactc agtcgcccgc tgaccagagc gttctcgagc
     4141 cctgcctgcc agttgtcgac tttgacaccc agtcggccac tcaaaggaaa acctgcatac
     4201 ggccagctcc agcgaccatc gcttacggtc aattgttgac gagtaatttg ccacggcaaa
     4261 tcgagcaacg gatcgccgtt atcccgtgcc agcacaatca attgcccgct attttcctgc
     4321 cagtccagct cggcatccac cagtgaaggc tcctgcggta agtttaacgt cgcagtagca
     4381 tgaccactta caggaagtcc atccggcacg agcggcatag taaattcccc caccagtttt
     4441 accggcggct gattttcaaa cgcgacgaca tccagttcgc tgactgtaag ttgttgccct
     4501 ttaagctggc cttgaaattt aactttttcg ccctgataac gcagttgctg gatatcggag
     4561 gttaatgcga gagagagttt tccctgccat tcctgccagg gagaaaaaat cagtttatcg
     4621 atattgatcc aggtgttagg caacatggcc tgccactgcg cgagggtttt gggagcggct
     4681 ggcgattgct ccgtctgcgg caatttcgcc agacaagcag aatcaagttc taccgtgccg
     4741 acgttcaata accagcggct gggatgtgaa aggctggcgt tggtgatatg cgcaagctga
     4801 caatctccca ccagataacg gagatcgggg atgattaaac ctttacgcgt aatgcgtggg
     4861 ctttcatcta atgcaatacg tgtcccgagc ggtagccaga tgcccgccag cgtgggaacc
     4921 cacagcccga gcgtcatcag cagcgtcaac ggcacaagaa taatcagtaa taacagcgcg
     4981 agaacggctt tatatttacc cagcatgggt agttaatatc ctgatttagc gaaaaattaa
     5041 gcattcaata cgggtattgt ggcatgttta accgttcagt tgaaggttgc acctacacta
     5101 agcatagttg ttgatgaat
//
LOCUS       DAFGPF010000209         4990 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFGPF010000209 DAFGPF010000000
VERSION     DAFGPF010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4990
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.211"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(381..1607)
                     /locus_tag="LSX49_005001"
     CDS             complement(381..1607)
                     /locus_tag="LSX49_005001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7171265.1"
                     /translation="MKETQATLPQTFYIKPGKFIWSYLGTFLFMLGGCIENSWLSAWL
                     NTQGFDQEHIGQIFAGYGIVVAITSWLSGVCVDLFGPKKVMVTGFIVYLLASVAFLNF
                     ALPSHDFGAILVTYMLRGVGYPLVCYSFLVRLTIQLDNHQQGIGTSLFWVVYNLGFTI
                     IGPVVAASLIPALGHINVMWAGMGVALLGVLFMLVLERNEFILKPRTTPVFKELSAGI
                     SIMYERPRIGLAVIVKTINGLGTYGFVVVLPLFLLDKHFTLEEWASIWGITFISNQVF
                     NIIFGWMGDKIGFRRTIQIFGSILTGVATLIVYWVPMIWGHNYVAFMLAMCLWGAGLA
                     GFVPMTPLVPMMAPDKKGAANSAVNFGSGLGNFVGPALVSVLAGFGTGVVMYTMAGLY
                     LFSGILVQFLKVPGEK"
     gene            complement(1680..2702)
                     /gene="iolG2"
                     /locus_tag="LSX49_005002"
     CDS             complement(1680..2702)
                     /gene="iolG2"
                     /locus_tag="LSX49_005002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-chiro-inositol-2-dehydrogenase IolG2"
                     /protein_id="HBL7171266.1"
                     /translation="MKKLRCGVIGLGRVGKMHVENMYLLPQLDIICAADYFIEEMSDW
                     LYSVNITSGYKNYQELLQRDDIEAVFIFTSTDMHEEIVTAAAQAGKHIFCEKPLSMNE
                     DEQASMAVLRKVKEKGVTLQVAFNRRFDPQFHEVFELVRSGKIGRPQMIKITSRDPDL
                     LPHDLIKRIGGLIFDFTMHDFDMARFMMQDEVSEVYVKGNTLIDPSLKNIDDVDTLAV
                     MLTFRNGGYALIDNSRRAVYGYDQRVEVFGSEGMAYADNVSESTVKVFNSQHCIMKNP
                     LPDFTVRYREAYRTEILHFIDSVLHHTPVVCTGEDALLAQRIAIAAQQSLKSGLPVKI
                     TSDIYL"
     gene            complement(2883..4823)
                     /gene="iolD"
                     /locus_tag="LSX49_005003"
     CDS             complement(2883..4823)
                     /gene="iolD"
                     /locus_tag="LSX49_005003"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HBL7171267.1"
                     /translation="MKTIRLTMAQALVRFLDNQYIDVDGSEIKFVKGIFAIFGHGNVV
                     GLGQALEEDCGQLSVHQGRNEQGMAHIATGFARQMRRHQIYACTSSVGPGAANMITAA
                     ATATANRIPLLLLPGDVYASRQPDPVLQQVEQEHDLTLSTNDAFRAVSRYWDRITRPE
                     QLMSACISAMRVLTDPADTGAVTLCLPQDVQGEAWDYPDYFFARRVYRLERHAPTEPM
                     LNEAVALIRRHQRPLIVCGGGVKYSQAEEALLRFAERCHLPIAETQAGKGALSSAHPL
                     NVGGIGETGSLAANLLAQEADLIIGVGTRYTDFTTSSKWIFQNPDVRYLNINVSRFDV
                     FKLDGVQMQGDARVALTQLSERLAQEHYASQWGETIHRVRSQYMAEVERVYAVEYSGE
                     GFKPEIEDHMDTQKVFEEFNEITRSWLTQTRVLGVLNRMLPENALVVAAAGSLPGDLQ
                     RVWQSRGENDYHVEYGYSCMGYEVNAALGAKLAQPEREVYSFVGDGSFMMLHSELVTS
                     VQMGKKITVILLDNMTNGCINNLQMEHGMDSYFTEFRFHQQESGRQEGGFIPVDFARI
                     AEGYGCKSYRVTTIEQLHEALEDARKQAVSTLIDIKVLPKTMVHKYLSWWRVGGAQVS
                     RSERIQAVARMLEEHIGQARQY"
BASE COUNT         1318 a         1395 c         1109 g         1168 t
ORIGIN      
        1 ttcacaggag gcagcaacga gctgctgttt aaattcggga ggataattag ggcagccttt
       61 tcgcctgccg ggagtcacat ttttctgcat atctgacact ttggttccca ctacttattt
      121 ggtggacacc actttgtcta attcgtcaga ttctgaccag acggttcagg ctgtacgctt
      181 accatttgtt aatacaaaac cgtgttttct cgatattcat tattttctcc ctgaacgtat
      241 atgagtgggt aaataaccgt aatccgttag tacaatttaa cgtagggtga aaaaaccggc
      301 tttatcaatc ttgataaaaa ccggtttaat ttagtgatga acatcacagg ctataaggga
      361 tttttgaaga atatttgaag ctatttttcg ccaggcactt taagaaactg caccagaatg
      421 ccgctgaata aatagagccc cgccatagta tacatcacca cgccggtgcc gaaccctgcc
      481 agaacggaga ccagcgctgg cccaacgaaa ttccccaggc cggagccaaa gttcacggcc
      541 gagttcgccg cccccttctt atccggcgcc atcatcggca ccagcggcgt cattggcaca
      601 aagccagcca gcccggctcc ccacaaacac atcgccagca taaaggcgac atagttatgc
      661 ccccatatca tcggcaccca gtaaacaatc agcgtagcga caccggtcag gatgctgcca
      721 aaaatctgga tggttcggcg aaaaccaatt ttatcgccca tccagccaaa gataatgttg
      781 aagacctggt tagagataaa ggtaatcccc caaatactcg cccattcctc aagcgtaaag
      841 tgcttatcca gcagaaacag aggtaatacg acaacaaaac cataggtgcc aagaccgtta
      901 atagttttga caatcaccgc cagaccgatc cgtggccgtt catacataat ggagataccc
      961 gcagataact ctttgaagac cggcgtcgtg cgcggtttca gaatgaattc attgcgttcc
     1021 agcaccagca tgaagagaac ccccagcagc gcaacgccca tcccggccca catcacgttg
     1081 atatgcccca acgcaggaat taacgacgcc gccaccaccg gcccaatgat ggtaaaacca
     1141 aggttataga ccacccaaaa cagcgaggtg ccgatccctt gctggtgatt atccaactgg
     1201 atggtcaggc gtaccaggaa ggagtaacaa accaacggat accccacgcc acgcagcata
     1261 taggtcacga gaatggcgcc aaaatcatgg ctgggtagcg caaagttcag aaacgcgacg
     1321 gaagccagaa gatagacgat aaaaccggta accatcacct ttttaggacc aaaaaggtcc
     1381 acacagacgc cggatagcca agaggtgatc gcgaccacaa tcccataccc ggcaaaaatc
     1441 tgcccgatat gctcctgatc aaatccctgc gtatttaacc aggcagataa ccagctgttc
     1501 tcaatacagc cgcccaacat aaataaaaat gttcccaggt agctccagat aaacttacct
     1561 ggttttatat aaaatgtctg gggcagcgtt gcctgcgttt ctttcatttt attaacctcg
     1621 gtatagaaaa gctctcacac ttttcagtgc gagagtttat tcattattaa cagatgcagt
     1681 caaagataaa tatcgcttgt tattttcacc ggcagcccgc tttttaatga ttgctgcgcg
     1741 gcaatagcga tacgctgggc caataatgcg tcttcgccgg tacagacaac cggcgtatga
     1801 tgcaggactg aatcaataaa gtgtaatatt tccgttcggt aagcttcgcg ataacggacc
     1861 gtgaaatcag gaagaggatt tttcattatg cagtgctggc tgttgaaaac tttcaccgtc
     1921 gattcactaa cgttatccgc atacgccatc ccttctgagc caaaaacctc cacccgttgg
     1981 tcatagccat ataccgcccg acggctgtta tcaatgagcg cgtagccgcc gtttctgaaa
     2041 gtcagcatca ccgcaagcgt atcaacatca tcaatatttt tcaggctggg atcaatcagc
     2101 gtattgccct taacatagac ttcgctgact tcatcctgca tcataaaacg agccatatca
     2161 aagtcatgca tggtgaagtc aaaaatcaga ccgccaatac gtttgatcag atcatggggt
     2221 agcaggtccg gatcgcggga ggtgattttt atcatctggg gccgaccaat cttgccgctg
     2281 cgcaccagct caaagacctc gtgaaactga ggatcaaaac ggcgattaaa ggcaacctgc
     2341 agcgtcaccc ccttctcttt cacttttctc agcaccgcca ttgaggcctg ctcatcttca
     2401 ttcatgctga gcggtttttc acaaaaaatg tgcttccccg cctgcgctgc cgccgtgacg
     2461 atctcttcgt gcatatccgt tgaggtgaaa ataaaaactg cctctatatc atcacgctgt
     2521 aaaagttcct gataattttt ataccctgaa gttatattta ccgaataaag ccaatcgctc
     2581 atctcctcaa taaaataatc ggcggcgcag ataatatcta attgaggcag taaatacata
     2641 ttttcaacat gcattttacc tacccgacca aggccaataa caccacatcg aagctttttc
     2701 attcgtacct cttaatctca tgaatagtaa atttaaaacc gcaaaagaaa agcatccgta
     2761 attctgcgaa aaacggatcg ttttattttg ccgttctgaa aagaaaacaa tgcgttgacg
     2821 ctgtatcgtt caggttgcag aacaataacc acacttctgc aacctgaacg acggcaaatt
     2881 aatcagtact gccgggcctg tccgatatgt tcctcaagca tacgcgctac cgcctggata
     2941 cgttcgctac gggatacctg cgccccgcca acgcgccacc agctcaggta cttatgcacc
     3001 atcgttttgg gaagcacttt tatgtctatc agcgtgctca cggcctgttt acgagcatct
     3061 tccaacgctt catgcagttg ttcaatggtg gtgacgcgat agcttttaca gccataccct
     3121 tcagcgatgc gagcgaaatc gaccgggata aacccgcctt cctgacgacc gctctcctgc
     3181 tgatggaaac gaaactcggt gaagtaactg tccataccgt gttccatttg cagattattg
     3241 atacagccgt tggtcatgtt atcgagcaaa atgacggtaa tctttttccc catctggacg
     3301 gaagtgacca actcagagtg cagcatcatg aacgaaccgt cgcccacgaa gctgtacacc
     3361 tcgcgctccg gctgcgccag tttggccccc aatgcggcat tgacttcgta gcccatacag
     3421 gagtagccgt actcgacgtg gtaatcattc tctccgcggc tttgccagac acgctggagg
     3481 tcgcccggca ggctgcccgc cgccgccacc accagcgcgt tttccggcaa catccggtta
     3541 agcacgccca acacgcgcgt ctgggtcagc cacgatcgcg taatctcatt aaactcttca
     3601 aacacctttt gagtatccat atgatcctca atttcaggtt tgaagccctc tccgctatat
     3661 tccacagcat agacgcgctc aacttccgcc atatattgcg agcggacgcg gtgaatagtc
     3721 tcaccccatt gcgaagcata atgctcctgg gccagccgtt cgctaagctg cgtcagggcg
     3781 acgcgagcgt caccctgcat ctgtacgcca tccagcttga agacatcaaa gcggctaacg
     3841 ttgatattta agtagcgcac gtcgggattc tggaagatcc actttgagga ggtggtgaaa
     3901 tcggtatagc gcgtccccac accgataatc agatcggcct cctgcgccag cagattcgcc
     3961 gccagtgaac cggtttcgcc aatcccgccg acattcaacg ggtgtgcaga actgagcgct
     4021 cccttgccag cctgggtttc agcaatcggc agatgacagc gttcggcaaa tctcagcagc
     4081 gcctcttcag cctgcgaata cttcacgccc ccaccgcaaa cgatcagcgg ccgctggtgg
     4141 cggcgaatca gcgcaaccgc ctcgttcagc atcggctccg tcggcgcgtg acgctcaaga
     4201 cgatagaccc ggcgagcgaa aaaataatcc ggataatccc aggcttcacc ctgcacatcc
     4261 tgtggcaggc aaagcgtcac ggcccccgta tccgccggat cggttaacac ccgcatcgcg
     4321 ctgatacagg cgctcattag ctgttccgga cgcgtaatgc gatcccagta gcggctaact
     4381 gcacggaaag cgtcattggt gctcagcgtc agatcgtgtt cttgttcaac ctgttgcaaa
     4441 accgggtcgg gttgacgaga tgcgtacaca tctcccggca gcaaaagcag tggaatacgg
     4501 ttagccgtcg cggtcgccgc tgcggtgatc atattggcgg cccctggccc cactgaggag
     4561 gtgcaggcat aaatctgatg gcgacgcatc tggcgggcaa atcccgtcgc gatatgcgcc
     4621 attccctgtt cgttacgccc ttgatgaacg ctaagttggc cacagtcctc ttccagcgct
     4681 tgccccaatc caacgacgtt cccgtggcca aaaatggcga aaatcccttt tacaaatttg
     4741 atttcgctgc cgtctacgtc gatgtactga ttatcaagaa agcgcaccaa agcctgcgcc
     4801 atggtcaacc tgattgtttt catgtacccc acctgctttt atcaaccgtt cggctgtcgt
     4861 tgcctgctta tgcatcgctt cagccccaaa aacacagaga cttatcatag gatcaaaatt
     4921 tccgttctca caattatatg gaatttacat ttcgtttatg ggaagtagat caaaaaacgg
     4981 taaaaaaatt
//
LOCUS       DAFGPF010000210         4901 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFGPF010000210 DAFGPF010000000
VERSION     DAFGPF010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4901
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.212"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            813..1325
                     /gene="hlyC"
                     /locus_tag="LSX49_005004"
     CDS             813..1325
                     /gene="hlyC"
                     /locus_tag="LSX49_005004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hemolysin-activating
                     lysine-acyltransferase HlyC"
                     /protein_id="HBL7171268.1"
                     /translation="MNMNNPLEVLGHVSWLWASSPLHRNWPVSLFAINVLPAIRANQY
                     ALLTRDNYPVAYCSWANLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGA
                     LYKYMRKKFPDELFRAIRVDPKTHVGKVSEFHGGKIDKQLANKIFKQYYHELITEVKN
                     KTDFNFSLTG"
     gene            1337..4411
                     /gene="hlyA"
                     /locus_tag="LSX49_005005"
     CDS             1337..4411
                     /gene="hlyA"
                     /locus_tag="LSX49_005005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RTX toxin hemolysin HlyA"
                     /protein_id="HBL7171269.1"
                     /translation="MPTITTAQIKSTLQSAKQSSANKLHSAGQSTKDALKKAAEQTRN
                     AGNRLILLIPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGL
                     TERGVTIFAPQLDKLLQKYQKAGNKLGGSAENIGDNLGKAGSVLSTFQNFLGTALSSM
                     KIDELIKRQKSGSNVSSSELAKASIELINQLVDTAASINNNVNSFSQQLNKLGSVLSN
                     TKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELT
                     TKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRAN
                     KIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSLVG
                     APVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHA
                     AFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYE
                     EGKRLEKKPDEFQKQVFDPLKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYE
                     YITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVF
                     LSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKILQEVVK
                     EQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIF
                     HGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYLNGGD
                     GDDELQVQGNSLAKNVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSG
                     YGHHIIDDDGGKDDKLSLADIDFRDVAFRREGNDLIMYKAEGNVLSIGHKNGITFRNW
                     FEKESGDISNHQIEQIFDKDGRVITPDSLKKALEYQQSNNKASYVYGNDALAYGSQDN
                     LNPLINEISKIISAAGNFDVKEERAAASLLQLSGNASDFSYGRNSITLTASA"
     gene            4482..>4901
                     /locus_tag="LSX49_005006"
     CDS             4482..>4901
                     /locus_tag="LSX49_005006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_063101322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HBL7171270.1"
                     /translation="MDSCHKIDYGLYALEILAQYHNVSVNPEEIKHRFDTDGTGLGLT
                     SWLLAAKSLELKVKQVKKTIDRLNFISLPALVWREDGRHFILTKVSKEANRYLIFDLE
                     QRNPRVLEQSEFEALYQGHIILIASRSSVTGKLAKFDF"
BASE COUNT         1578 a          828 c         1090 g         1405 t
ORIGIN      
        1 ttttactatg tcttatggtg taatgcgcta acctgtttcg atacggtaat agatataccc
       61 accatattga acatttgtag atcattattc tatagtgctc agagttaaaa tcgtctctgg
      121 ttgaattgat ttgttacaca ggattctggt cccggttgat acgggtaatt tccggaaggg
      181 cggtagcatg cttattcaaa atacaatatg agacacggtc gaagtcggat ggaattaaat
      241 catggctaca gcatttttgt gtgtatgata taattttgcc tcatatttta gagtatactt
      301 gcgcacccgc caatagagtc gccttctttt gcgtgctggg atcgtactgt atgagataca
      361 ctttgaatca ttatccgaag tcagaagaag cgcattgact ggtatgacct gattaattca
      421 accccttatc tgacaggggt agaaaaagaa gagaggttca catgataact cacaggtcat
      481 cattcggcag ctgattggta ctgggtaagg aagttatata tataagcaac tatacatctt
      541 agatgtatga taaagaaaaa gataacagtt ctttagaatg tgcatattga agagaataca
      601 atagcatggt ttatataaat tacgcataaa aataagcata tgtaagcatt ttggtttgct
      661 tttttttacc tgccaccgca atgaatgctt tttttatgtt aatgtgcgtt atgaaactaa
      721 atgcaagaaa catatttaaa ggattaatat cgttctctca cagactccgt ttacttattc
      781 aagaatataa tttaatttat agtgagctta ttatgaatat gaacaatcca ttagaggttc
      841 ttgggcatgt atcctggctc tgggccagtt ccccattaca cagaaactgg ccagtctctt
      901 tgtttgcaat aaatgtatta cctgcaatac gggctaacca atatgcttta ttaacccggg
      961 ataattaccc tgttgcatat tgtagttggg ctaatttaag tttagaaaat gaaattaaat
     1021 atcttaatga tgttacctca ttagtcgcag aagactggac ttcaggtgat cgtaaatggt
     1081 tcattgactg gattgctcct ttcggggata acggtgccct gtacaaatat atgcgaaaaa
     1141 aattccctga tgaactattc cgagccatca gggtggatcc caaaactcat gttggtaaag
     1201 tatcagaatt tcacggaggt aaaattgata aacagttagc gaataaaatt tttaaacaat
     1261 attaccacga gttaataact gaagtaaaaa acaagacaga tttcaatttt tcattaacag
     1321 gttaagagat aattaaatgc caacaataac cactgcacaa attaaaagca cactacagtc
     1381 tgcaaagcaa tcctctgcaa ataaattgca ctcagcagga caaagcacga aagatgcatt
     1441 aaaaaaagca gcagagcaaa cccgcaatgc gggaaacaga ctcattttac ttatccctaa
     1501 agattataaa ggacagggtt caagccttaa tgaccttgtc aggacggcag atgaactggg
     1561 aattgaagtc cagtatgatg aaaagaatgg cacggcgatt actaaacagg tattcggcac
     1621 agcagagaaa ctcattggcc tcaccgaacg gggagtgact atctttgcac cacaattaga
     1681 caaattactg caaaagtatc aaaaagcggg taataaatta ggcggcagtg ctgaaaatat
     1741 aggtgataac ttaggaaagg caggcagtgt actgtcaacg tttcaaaatt ttctgggtac
     1801 tgcactttcc tcaatgaaaa tagacgaact gataaagaga caaaaatctg gtagcaatgt
     1861 cagttcttct gaactggcaa aagcgagtat tgagctaatc aaccaactcg tggacacagc
     1921 tgccagcatt aataataatg ttaactcatt ttctcaacaa ctcaataagc tgggaagtgt
     1981 attatccaat acaaagcacc tgaacggtgt tggtaataag ttacagaatt tacctaacct
     2041 tgataatatc ggtgcagggt tagatactgt atcgggtatt ttatctgcga tttcagcaag
     2101 cttcattctg agcaatgcag atgcagatac cggaactaaa gctgcagcag gtgttgaatt
     2161 aacaacgaaa gtactgggta atgttggaaa aggtatttct caatatatta tcgcacagcg
     2221 cgctgcacag gggttatcta catctgctgc tgctgccggt ttaattgctt ctgtagtgac
     2281 attagcaatt agtcccctct cattcctgtc cattgccgat aagtttaaac gtgcaaataa
     2341 aatagaggag tattcacaac gattcaaaaa acttggatac gatggtgaca gtttacttgc
     2401 tgcttttcac aaagaaacag gagctattga tgcatcgtta acaacgataa gcactgttct
     2461 ggcttcagta tcttcaggta ttagtgctgc tgcaacgaca tctctggttg gtgcaccggt
     2521 aagcgcgctg gtaggggctg ttacggggat aatttcaggc atccttgagg cttcaaaaca
     2581 ggcaatgttt gaacatgtcg ccagtaaaat ggccgatgtt attgctgaat gggagaaaaa
     2641 acacggcaaa aattactttg aaaatggata tgatgcccgc catgctgcat ttttagaaga
     2701 taactttaaa atattatctc agtataataa agagtattct gttgaaagat cagtcctcat
     2761 tacccagcaa cattgggata cgctgatagg tgagttagcg ggtgtcacca gaaatggaga
     2821 caaaacactc agtggtaaaa gttatattga ctattatgaa gaaggaaaac gtctggagaa
     2881 aaaaccggat gaattccaga agcaagtctt tgacccattg aaaggaaata ttgacctttc
     2941 tgacagcaaa tcttctacgt tattgaaatt tgttacgcca ttgttaactc ccggtgagga
     3001 aattcgtgaa aggaggcagt ccggaaaata tgaatatatt accgagttat tagtcaaggg
     3061 tgttgataaa tggacggtga agggggttca ggacaagggg tctgtatatg attactctaa
     3121 cctgattcag catgcatcag tcggtaataa ccagtatcgg gaaattcgta ttgagtcaca
     3181 cctgggagac ggggatgata aggtcttttt atctgccggc tcagccaata tctacgcagg
     3241 taaaggacat gatgttgttt attatgataa aacagacacc ggttatctga ccattgatgg
     3301 cacaaaagca accgaagcgg gtaattacac ggtaacacgt gtacttggtg gtgatgttaa
     3361 gattttacag gaagttgtga aggagcagga ggtttcagtt ggaaaaagaa ctgaaaaaac
     3421 gcaatatcgg agttatgaat tcactcatat caatggtaaa aatttaacag agactgataa
     3481 cttatattcc gtggaagaac ttattgggac cacgcgtgcc gacaagtttt ttggcagtaa
     3541 atttactgat atcttccatg gcgcggatgg tgatgaccat atagaaggaa atgatgggaa
     3601 tgaccgctta tatggtgata aaggtaatga tacgctgagg ggcggaaacg gggatgacca
     3661 gctctatggc ggtgatggca atgataagtt aattgggggg acaggtaata attaccttaa
     3721 cggcggtgac ggagatgatg agcttcaggt tcaggggaat tctcttgcta aaaatgtatt
     3781 atccggtgga aaaggtaatg acaagttgta cggcagtgag ggagcagatc tgcttgatgg
     3841 cggagaaggg aatgatcttc tgaaaggtgg atatggtaat gatatttatc gttatctttc
     3901 aggatatggc catcatatta ttgacgatga tggggggaaa gacgataaac tcagtttggc
     3961 tgatattgat ttccgggatg tggccttcag gcgagaaggt aatgacctca tcatgtataa
     4021 agctgaaggt aatgttcttt ccattggtca taaaaatggt attacattca ggaactggtt
     4081 tgaaaaagag tcaggtgata tctctaatca ccagatagag cagatttttg ataaagacgg
     4141 cagggtaatc acaccagatt cccttaaaaa ggcacttgag tatcaacaga gtaataataa
     4201 ggcaagttat gtgtatggga atgatgcatt agcctatgga agtcaggata atcttaatcc
     4261 attaattaat gaaatcagca aaatcatttc agctgcaggt aattttgatg ttaaagagga
     4321 aagagctgca gcttctttat tgcagttgtc cggtaatgcc agtgattttt catatggacg
     4381 gaactcaata actttgacag catcagcata atttattaat ttaaataata gcaatcttac
     4441 tgggctgtgc cacataagat tgctattttt ttggagtcat aatggattct tgtcataaaa
     4501 ttgattatgg gttatacgcc ctggagattt tagcccaata ccataacgtc tctgttaacc
     4561 cggaagaaat taaacataga tttgacacag acgggactgg tctgggatta acgtcatggt
     4621 tgcttgctgc gaaatcttta gaactaaagg taaaacaggt aaaaaaaaca attgaccgat
     4681 taaactttat ttctttgccc gcattagtct ggagagagga tggacgtcat tttattctga
     4741 ctaaagtcag taaagaagca aacagatatc ttatttttga tctggagcaa cgaaatcccc
     4801 gtgttctcga acagtctgag tttgaggcgt tatatcaggg gcatattatt cttattgctt
     4861 cccgttcttc tgttaccggg aaactggcaa aatttgactt t
//
LOCUS       DAFGPF010000211         4821 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFGPF010000211 DAFGPF010000000
VERSION     DAFGPF010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4821
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.213"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            104..571
                     /locus_tag="LSX49_005007"
     CDS             104..571
                     /locus_tag="LSX49_005007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7171271.1"
                     /translation="MLKTNSLRESMLHGCRWCQANPEKFTIFVESGNIETTGEAPSFV
                     YRYQMVMFVMDYAGELDDLTLPLLAWLSENQPQLLLNPERNQDIKFSAVINDDDSADL
                     LFTLPLRERVRITRNSQGTPQAEHLPEPKPRLPSSEGDWSHVFQDVTWGESDG"
     gene            564..1199
                     /locus_tag="LSX49_005008"
     CDS             564..1199
                     /locus_tag="LSX49_005008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HBL7171272.1"
                     /translation="MDKAFTRVDETFEAIRDSLNQQAINNIARKLAQDLRRAQQARIR
                     SQKAPDGTEWTPRRRRVTRIQERIRFIWNNEARTLKNWHHDTGKYGRTITGWDEDKNN
                     IRTFYRDDIDRFLEIRTRRINQDSTKRVPMFVKLRTARYLKARADASGVTVGYSGVAA
                     RIARVHQFGERDQVAPGIFTDYPVRELLGISQADERLIYNTVLGRIAEAVR"
     gene            1211..1777
                     /locus_tag="LSX49_005009"
     CDS             1211..1777
                     /locus_tag="LSX49_005009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HBL7171273.1"
                     /translation="MRLLSNIIRTGIISEVDEKSWRVRVRSGELETGWLRWNTTRAGA
                     FNVWLPPSPGEQVVIACIGGNPETAMIIGSLWSDASPAPGKSLKEIVVSAPDGAVFRY
                     DADAGALSASGMKTATLQASVSVTLDTPVVECTNLLRTATLDVTKEGKMSGNITHSGG
                     NFTSNGITVHTHKHGGVKGGSDSTGGPQ"
     gene            1795..2124
                     /locus_tag="LSX49_005010"
     CDS             1795..2124
                     /locus_tag="LSX49_005010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001705832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HBL7171274.1"
                     /translation="MNPDGTGNLNDMEHLKQSVRDILITPLASRVMRREYGSLVPDLI
                     DEPMNNTTRLQCMSAAVIALTRWEPRIALDAIDVVWKAGGRAGVTLSGTVMQTMQNVE
                     LTITLRE"
     gene            2128..3024
                     /locus_tag="LSX49_005011"
     CDS             2128..3024
                     /locus_tag="LSX49_005011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBL7171275.1"
                     /translation="MPAVDLSQLPEPAIIAEPDFEAILADTKAMMIASYPAEQREAVS
                     AALELESEPLNVIAQTMSFREMLLRQRVNEGARACMLSHGSGTNLDNLAGNMNTKRLV
                     ITPATDTTDAVMESDTSLRLRAQRAYDGLSVAGPSGAYEYFARSASGLVRDARAISPS
                     PACVTVSILSTEGDGTATEALLNTVRAVLNAEDTRPVADRLTVQSASIVTWRLNAKLY
                     FYPGPESEPILAAAESSFRKWLAEQGLIGQDVALSAIAAALHVHGVQRVEIIEPTQNM
                     AISDIQAARCESFTISEGGRNE"
     gene            3017..3547
                     /locus_tag="LSX49_005012"
     CDS             3017..3547
                     /locus_tag="LSX49_005012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HBL7171276.1"
                     /translation="MSNSLLPPSASNFMRCAEAVGARITDIPVDLNTLWSPDTCPVHL
                     LPYLAWAFSVDRWDRNWPEETKRQVIRDAWLIHRHKGTISALRRAIEPLGYLIRVSEW
                     WEFGGEPGTFTVEVGTLDSGVTEEMYLEMERLIADARPVSRHMTGLNIIQEIQGDIFA
                     AAATYDGEVITIYPDD"
     gene            3550..>4821
                     /locus_tag="LSX49_005013"
     CDS             3550..>4821
                     /locus_tag="LSX49_005013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HBL7171277.1"
                     /translation="MSTTTRKFKTVITDTGAKKLAQAAAPDGKPVRLTHMAVGDGGGT
                     LPTPDSKQTRLVHEVWRHTVNRVILDATHQNRIIAELVIPPETGGFWIREIGVFDEHG
                     DLIAVGNTAESYKPAVAEGSGRAQTFRTILTVSSTATVVLTVDNTMVMATVDYVDDKL
                     KEHEQSRRHPDASLTAKGFVQLSSATNSVSETQAATPKAVKAAYDLANGKYTAQDAST
                     TRKGLVQLSSATNSTSETQAATPKAVKAAYDLANAKYTAQDATTAQKGIVQLSSATNS
                     TSETLAATSKAVKAVMDETNKKAPLNSPALTGTPTTPTARQGTNNTQIASTAFVMAAI
                     AALVDSSPDALNTLNELAAALGNDPNFATTMTNALAGKQPKDATLTALAGLTTAAGKF
                     PYFTGNDVASLATLTKVGRDILAKSTVAAVIE"
BASE COUNT         1181 a         1337 c         1386 g          917 t
ORIGIN      
        1 taactgatat cactaaaaat gccgcgtacg gcgtcgatat cggcagcctg gtgctggaaa
       61 tcaataatcc cgcagcataa ggaagagcag gagagcaaaa cagatgctta agacaaacag
      121 tctgcgagag tccatgcttc atgggtgtcg gtggtgccag gctaatcccg agaaattcac
      181 cattttcgtg gagagcggca acattgaaac gaccggagaa gcgccctcgt ttgtttaccg
      241 ctatcagatg gtgatgtttg tcatggatta cgccggagag ctggacgacc tcacgctgcc
      301 gctgctggcg tggttatccg aaaatcagcc acagttgttg ctcaatccgg agcgtaatca
      361 ggacatcaaa ttttctgccg ttatcaatga cgatgacagc gccgatctcc tgtttacgct
      421 ccccctgcgg gaacgcgttc gcatcacgcg caacagtcag ggcacaccgc aggcagaaca
      481 cctgccggag ccaaaacccc gtctgccttc ttccgaaggc gactggtcgc atgtattcca
      541 ggatgtgacg tggggtgaaa gcgatggata aggcattcac ccgcgtggat gaaacctttg
      601 aggctatccg cgacagcctg aatcagcagg ccatcaataa catcgccaga aagctggcac
      661 aggatttacg tcgcgcccag caggcacgta tccggtcaca aaaagcgccg gacgggaccg
      721 aatggacacc acgcagacgc cgcgtaaccc ggatacagga gcgcattcgc tttatctgga
      781 ataacgaagc acgcacgctg aaaaactggc atcacgacac agggaaatac gggcgaacca
      841 ttaccgggtg ggatgaggat aaaaacaata tccgcacgtt ttaccgggat gacatcgacc
      901 gttttctgga aatacgcacc cggcgcatca accaggacag cacaaagcgc gtccccatgt
      961 tcgtaaaact gcgcaccgcc cgctacctga aagcccgtgc agatgcctcc ggtgtgacgg
     1021 tgggttacag cggcgtggcc gcacgtattg cacgcgttca tcagttcggt gagcgcgatc
     1081 aggttgcgcc gggcattttc accgattacc cggtacgtga gctgttgggt atcagccagg
     1141 cagatgagcg cctgatttat aacacggtgc tgggccggat tgcggaggct gtacggtgag
     1201 cgcagaactc atgcgactgc tgagcaacat catccgcacc gggatcatct ctgaagttga
     1261 tgagaagtcc tggcgcgtgc gcgttcgcag cggcgaactg gaaacaggct ggttgcgctg
     1321 gaacaccacg cgcgcgggag ccttcaatgt gtggctgccg ccatcaccag gcgaacaggt
     1381 ggtaattgcc tgcattggcg gcaacccgga aaccgccatg ataattggca gcctgtggag
     1441 tgatgccagt ccggcccccg gcaaaagcct gaaagaaatc gtggtcagcg cgccggatgg
     1501 cgcggtgttc cgctacgacg cagacgctgg cgcactgagc gccagcggca tgaaaacagc
     1561 caccctgcag gcatccgtca gcgtgacact ggatacgccc gtcgtggaat gcacaaacct
     1621 tctgagaacg gcgacgcttg acgtcacaaa agagggaaag atgagcggca atatcacgca
     1681 cagcggcggc aatttcacct caaacggcat taccgtgcat acgcataagc acggtggcgt
     1741 taaaggtggc agcgattcga caggaggccc gcagtgacaa cccgctacac aggaatgaac
     1801 ccggacggga cgggaaacct gaacgatatg gagcacctga aacagtcagt cagggacatc
     1861 ctgatcaccc cgctggcaag ccgggttatg cgacgggaat atggcagcct tgtgcctgat
     1921 ttgattgacg aacccatgaa taacaccacg cgtctgcaat gcatgagtgc tgccgtgatt
     1981 gcgctgacac gatgggaacc ccgcattgcc ctggacgcca tcgacgttgt ctggaaggca
     2041 ggaggccgcg ccggggtgac gctgtcgggc actgtcatgc agaccatgca gaatgttgaa
     2101 ttaaccatca cgctgagaga gtaaatcatg cctgctgttg atctttccca gttaccggaa
     2161 cccgccatca tcgcggagcc tgattttgag gcaattctgg ctgacacaaa ggccatgatg
     2221 attgcgtcct atcctgccga acagcgtgaa gccgtctccg ccgcgctgga gctggaatca
     2281 gaacccctga acgttatcgc tcaaaccatg tcgtttcgtg aaatgctgtt acgccagcgg
     2341 gttaacgagg gcgcacgcgc ctgcatgtta agccacggtt cagggacaaa cctggacaac
     2401 ctcgcgggca atatgaacac aaagcgcctg gttatcactc cggcaacgga taccaccgac
     2461 gcggtgatgg agagcgacac ctcgctgaga ctgcgggcgc agcgggcgta tgacggcctg
     2521 agtgttgctg gcccgtcagg tgcatacgag tattttgcac gcagcgccag cggtctggtg
     2581 cgtgatgcgc gggccatcag cccgtctccg gcctgtgtga cggtttccat tctgtccact
     2641 gaaggcgacg gcacagcaac ggaggcgttg cttaataccg ttcgcgccgt tctgaatgca
     2701 gaggataccc gcccggtggc cgaccgactg accgtacaga gcgccagcat cgtgacatgg
     2761 cggctgaatg caaaactgta cttttacccc ggcccggaat ccgaacctat tctggctgcg
     2821 gctgaatcgt cgttcaggaa gtggctggct gagcaggggc ttattggtca ggacgtggcg
     2881 ttgtcagcca ttgctgccgc acttcatgtg cacggcgtgc aacgcgtgga gataatcgaa
     2941 cccacacaga atatggccat cagcgacata caggcggcgc gctgtgagtc attcaccatc
     3001 agcgaaggtg ggcgtaatga gtaattcact gttaccgcca tcagccagca atttcatgcg
     3061 ttgcgccgaa gctgtcggag cgcgcattac agacatcccg gtagacctca acacgctgtg
     3121 gtcaccggac acctgcccgg tgcatctgct gccttatctc gcctgggcat tttccgttga
     3181 ccgctgggat cgcaactggc cggaagagac aaagcgacag gtgattcgtg atgcatggct
     3241 gatacaccga cacaaaggga ccatcagcgc actgcgccgg gccattgagc cgctgggata
     3301 cctcattcgc gtgtctgagt ggtgggagtt cggcggagaa ccgggaacat ttaccgttga
     3361 agtcggcacg ctggacagtg gcgtgacgga ggaaatgtat ctggaaatgg agcggttgat
     3421 tgctgatgcc cgcccggtca gccgccacat gacagggctg aatatcattc aggagattca
     3481 gggagatatt ttcgcggcgg cagcaactta cgacggcgaa gtcattacca tttatccgga
     3541 cgattaagca tgagtaccac aacacgtaaa tttaaaaccg ttatcaccga tacgggtgcc
     3601 aaaaaattag ctcaggcagc cgcgccagat ggtaagcctg tccgcctgac tcatatggcc
     3661 gtgggcgacg gtggcggcac gttgcccaca ccagacagta agcagacccg tctggtgcat
     3721 gaggtgtggc gacatactgt taatcgcgtc atcctggacg caacacatca gaaccgcatt
     3781 attgcggagc tggttattcc tcctgaaacg ggcggattct ggatccggga aattggtgta
     3841 tttgatgagc acggcgattt aatcgcggtg ggcaatactg ccgaaagtta caagccagcc
     3901 gttgccgaag ggtccggtcg tgcacaaaca tttcgcacca ttctgaccgt atccagcact
     3961 gccaccgtgg tgcttaccgt ggataacacc atggtgatgg ccacagtgga ttacgtggat
     4021 gacaaactga aagagcatga acagtcacga cgtcacccgg acgcctcgct gaccgcaaaa
     4081 ggctttgttc aactcagtag cgccactaac agcgtgtctg aaacgcaggc tgcaacgccg
     4141 aaagcagtaa aggccgcgta tgaccttgct aacggtaaat atactgcgca ggatgccagc
     4201 acgacgcgaa aaggccttgt ccagctcagt agcgccacca acagcacgtc tgaaacgcag
     4261 gctgcaacgc cgaaagcagt aaaggccgcg tatgaccttg ctaacgcaaa atataccgct
     4321 caggacgcca cgacggcaca aaaagggata gtccagctca gtagtgccac caacagcacg
     4381 tctgaaacac tggccgcgac atcgaaagct gttaaggcgg taatggatga aacgaacaag
     4441 aaagcgccct taaatagtcc tgcactgacc ggaacgccaa caacaccaac tgcgcgacag
     4501 ggaacgaata atacccaaat cgcaagcacg gctttcgtta tggctgcgat tgccgccctt
     4561 gtagattcgt cacctgatgc actgaacacg ctgaacgagc tggctgcggc gctgggcaac
     4621 gacccgaatt ttgcgaccac catgactaac gcgcttgcgg gtaagcaacc gaaagatgcc
     4681 accctgacgg cgctggccgg acttactact gcggcaggca agtttccgta ttttacgggg
     4741 aatgatgtcg ccagcctggc aaccctgaca aaagtcgggc gggatattct tgcgaaatcg
     4801 accgttgctg ccgttatcga a
//
LOCUS       DAFGPF010000212         4790 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFGPF010000212 DAFGPF010000000
VERSION     DAFGPF010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4790
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.214"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(138..902)
                     /locus_tag="LSX49_005014"
     CDS             complement(138..902)
                     /locus_tag="LSX49_005014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBL7171278.1"
                     /translation="MNNQTIRTSVPALDKTVRVCNYLFSSPGATFSQIQQDLDLPKSS
                     TSSLLNALVEHHLLRQERGRFFLGLKLYEWGNRSLEQFDISKVARPVLEKLRDSTDLI
                     CHLGILDEVAPIYILKLESTQPIGIRTWVGKKLPLHSSGVGKALCAWLPQDVIDTLLP
                     EETLPRFTQTTITRKSDLIQEFARIRERGWAFDNAEDSPGIYCIAAPVFNQTREVIAA
                     ISISGVEIQIPKEKIEYYSTLVLDACQELSEKLKYI"
     gene            1142..2041
                     /locus_tag="LSX49_005015"
     CDS             1142..2041
                     /locus_tag="LSX49_005015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBL7171279.1"
                     /translation="MLTAFRGIFPPVPTIVDAQGKLDKAGMARMIDHVLENGANGMLI
                     LGSGGEFSQFSSQQRKEIAAFCLSHVDGKVPVLVGIACAGTAETIDLGHHAQEHGADG
                     VMVVNPYYAKLSDDARFMHYKSIADSLKIPVFLYNFPDLTGQDIGLEVITRLAREVPN
                     IVGIKDTIDNISHTREVINRVHAFRPDFIIFSGYDEYMLDTLLLGGHGGIPATFNFAP
                     NITRGIYQAVMENDLDKARYFQQQLAKLSPLYTLEQPFFGVIKTAIKLSGLDISTAVM
                     APALPLSDDKVARVKAILEHIHQ"
     gene            2058..3575
                     /locus_tag="LSX49_005016"
     CDS             2058..3575
                     /locus_tag="LSX49_005016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL7171280.1"
                     /translation="MNKTPILKLNNSDDVVIARTELPAGSWLESESMETRDLIPAGHK
                     IALRDIPAGSAVKRYGQIIGFATRDIRQGEHIHVHNLGMGSFERDYAWGIDSHLPEKD
                     VHQDTFMGIRRKDGRVATRNYIGVLSSVNCSATVVRAIEDHFRTRGLSDYPNVDGIVA
                     LPQSFGCAFGSDSEMMKVMRRTMAGYATHANFAGIVIVGLGCESFQIKDMMNAHGLHE
                     SPVFHTMTIQESGGTRNAIEKGISFILDMLPEANNVKREPVPVSEIILALECGGSDSY
                     SGISANPALGYAVDRLVRQGGTAILSETSEIYGAEHLLTRRAISREVGEKLIRRIKWW
                     EEYCKRTGSEMNNNPSAGNKAGGLTTVLEKSLGGIAKAGTTSLMDVYEYAEPVTAKGL
                     VFMDTPGYDPMAVTGQIAGGANLLCFTTGRGSAFGAKPTPCLKLSTNNALWQRQRDDM
                     DLNCGTIVDGEETIEQVGERIYQRIIELASGHRSRSEELGYGSQEFVPWIMNSIM"
     gene            3653..4666
                     /locus_tag="LSX49_005017"
     CDS             3653..4666
                     /locus_tag="LSX49_005017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HBL7171281.1"
                     /translation="MERKPVLGIFLGEAAGIGPELVAKVVADGTVYKYCRPVLIGDAR
                     VLALGQKIAGVHFQWNVISDPTEADWTTGNVPLLDLKNFNPEKLTMGTIDTDSGYATG
                     ESLVTCMSLLKSGKIDGFVFAPLNKEAFKKGGWDIEDEHYLFAEQLGYLDKPRGLLNV
                     LGDLWVFRVTGHIPFKDIASHITPENVSRSIQLCYDTLRMAAVENPRIAVAALNPHAG
                     DGGTCGKEEIDVLIPVIEGFREKGMDMYGPVPGDTVFIHAFNHEYDAVVTLFHDQGQI
                     ATKLHSFDVGITVAAGLPFAITTPEHGTAFDIAGKGIAKTLATERAIAVAARMASTVH
                     KDN"
BASE COUNT         1353 a          995 c         1119 g         1323 t
ORIGIN      
        1 taaaataaaa tcatcgctta aaaagaaaaa cactctcttt gttatatacg tactctgata
       61 aatgccagat aaaactatta attttcataa aaatataata ccatatatta tgatgctata
      121 catcttacat attcaattca gatatatttt aatttttccg atagttcttg acacgcatca
      181 agaaccaaag ttgaataata ttcaattttt tctttaggta tctgaatttc cacgccacta
      241 atgctgatag ctgcaattac ttcacgagtc tgattaaata ccggagcagc aatacaataa
      301 attcccggtg aatcctctgc gttatcaaaa gcccatccac gttcacgaat acgtgcaaat
      361 tcctgtatta gatcagattt acgagtgata gttgtttgcg taaatcgtgg caacgtttcc
      421 tcaggcaaca atgtgtcaat gacgtcttga ggtaaccacg cacataaagc cttaccaact
      481 ccagaactat ggagtggcaa cttcttgcct acccacgttc tgatgccaat tggttgtgta
      541 ctctcgagtt tcaaaatata gattggagcg acttcatcga gaatgcccag atggcagata
      601 agatcagtac tgtctctcag tttttctaga accggcctcg ctaccttact gatgtcaaac
      661 tgctccagag atcgattccc ccattcatac aatttcagcc caagaaaaaa acgccctctt
      721 tcctgacgta acagatgatg ttcgacaagg gcattcagta aagatgatgt gctgcttttt
      781 ggcagatcca gatcctgctg gatctggctg aaggtggcgc ctggagagct aaaaaggtaa
      841 ttgcagactc tgacagtttt atcgagtgct ggtaccgatg ttctgatggt ttgattattc
      901 ataaaaaaat atgattcctt acaatactga atagtatacc ccattccccc ttgatgcgca
      961 gcggcgctta gcacacatat tatacatggc ctccgcgtac cggcatgcct ctataaacct
     1021 gacttatttc acacttttca tatcgcattg taaaaacatt tgacatgcaa aacctgaatt
     1081 tgattcactt tattcagcat aaagaacttg tgttccatat acagaactta gtgagagtga
     1141 tatgttgaca gcgtttagag gtattttccc gccagttcct acaattgttg acgcacaagg
     1201 gaaactagat aaggctggca tggccaggat gatcgaccat gttttagaaa atggtgcaaa
     1261 cgggatgttg atccttggca gtgggggaga attctcacaa ttttcttccc agcaacgaaa
     1321 agagatagct gcattttgct taagtcatgt agatggcaaa gtgcctgttc tggtggggat
     1381 cgcctgcgcg ggaactgcag aaactattga tttaggacat catgcacagg agcacggagc
     1441 tgatggtgtg atggtggtga atccgtatta tgcaaaactc agcgatgatg cccggtttat
     1501 gcattacaaa tctattgccg attcacttaa aattccagtg tttctctata actttcctga
     1561 tctgaccggt caggatattg ggcttgaggt cattacccgg ctggcccggg aagttccaaa
     1621 tatcgtgggt atcaaggata ccatcgataa tatcagccat acccgggaag tcatcaaccg
     1681 tgtacatgct tttcgtccgg atttcattat attcagcgga tatgacgaat atatgctgga
     1741 taccctgtta ctgggcggcc atggtggtat tccggcgaca ttcaattttg ctccaaatat
     1801 cacacgtggt atttatcagg ccgttatgga aaatgatctt gataaagcgc gttattttca
     1861 gcaacaactg gcaaaactgt ctccgttata cacactggag cagcctttct ttggcgtgat
     1921 aaaaactgcc atcaaactga gtggactgga catatctact gcagttatgg caccggctct
     1981 tccgctcagt gatgacaagg tcgccagggt gaaagccatt ctggaacaca ttcaccagtg
     2041 attacgagga tcgtaagatg aataagactc cgatactcaa attaaataac tcggatgatg
     2101 tcgttattgc caggacagaa cttcctgccg gaagctggct ggaatctgaa agtatggaaa
     2161 cacgtgacct tattccggca gggcacaaaa ttgctcttcg ggatattccg gccggcagtg
     2221 ccgttaaacg ctatggacag ataatcggtt ttgcgacccg tgacatccga cagggcgaac
     2281 atattcatgt gcataatctc ggtatgggga gttttgagcg tgattatgcc tgggggatag
     2341 acagtcatct tccggaaaag gatgttcatc aggatacctt tatggggatc cgcagaaaag
     2401 acggacgggt ggcaacccgt aattatattg gtgtactgag ttctgtaaac tgtagtgcaa
     2461 ccgtagtaag ggcaattgaa gatcatttcc gtacccgtgg tctcagtgat taccctaatg
     2521 tggatggtat tgttgccctc ccacaaagtt ttggttgtgc ctttggctct gacagcgaaa
     2581 tgatgaaagt catgcggagg acaatggcag gctatgccac gcacgcgaac tttgccggga
     2641 tcgtgatcgt gggactggga tgtgaatcat tccagattaa ggacatgatg aatgcccacg
     2701 gattacatga aagtcctgta ttccatacaa tgactattca ggaaagcggc ggaacacgta
     2761 acgctataga aaaaggtatt tccttcattc tcgacatgct cccggaagcc aacaatgtca
     2821 aacgagaacc agttccggta tcagaaatca ttctggctct tgagtgtggc ggctctgata
     2881 gctattcagg aatttccgct aatccggctc tcgggtacgc agttgatcgc ctggttcgcc
     2941 agggaggaac ggctattctg tcggaaacat cggaaattta tggagcagaa caccttctga
     3001 cacgccgtgc cattagtcgc gaagttggcg agaaactaat ccgcagaatt aagtggtggg
     3061 aagagtactg taaacgtaca gggagtgaaa tgaataacaa cccttctgca ggtaataaag
     3121 cggggggact gaccactgtt ctggagaaat cgctgggagg gatagcaaaa gctggtacaa
     3181 ccagcttaat ggatgtgtat gaatatgctg aaccggtgac agcaaaaggg cttgtcttta
     3241 tggatacccc cggatatgac ccgatggcag taaccggaca aatcgccgga ggagccaacc
     3301 tgctgtgttt taccacgggc aggggatctg cctttggcgc aaaacccact ccttgtctga
     3361 aactgtcaac caataacgca ctatggcaac ggcagcgcga cgacatggat ttaaactgtg
     3421 gcacgattgt tgatggcgaa gaaacaatag aacaggttgg agaacgtatt tatcagagaa
     3481 ttattgagct ggcttcaggt catcgtagtc gaagtgaaga gctgggttat gggagccagg
     3541 aattcgttcc ttggataatg aactcaatca tgtaataact acgggcataa tttgttttgc
     3601 ccggaaataa ggaaacaaac tgaatcctgt ttttgataat tagaggtgaa taatggaacg
     3661 taaaccagta ctgggcattt ttttaggtga agctgccggc attggacctg aactggttgc
     3721 caaagtcgta gctgatggta ctgtctataa atattgcaga cctgttctga ttggcgatgc
     3781 ccgggtactt gctcttggac aaaagattgc tggtgtgcat tttcagtgga atgtcatcag
     3841 tgatcccact gaagctgact ggactacggg aaatgtacca ttacttgatt tgaaaaattt
     3901 taatcccgaa aaactaacta tgggcaccat tgataccgac tcaggttatg caacaggaga
     3961 atcactggta acctgtatgt cattacttaa atcaggtaaa attgacggtt ttgtcttcgc
     4021 tccactcaat aaagaagctt tcaagaaggg gggctgggat attgaggacg aacattatct
     4081 ctttgctgag cagttaggat atttggataa acctcgtggc ctgttgaatg tccttggtga
     4141 cctctgggtt tttcgcgtga cgggacatat tccattcaaa gatattgcca gccatattac
     4201 accagaaaat gtcagtcgtt cgattcagtt atgctatgac acattacgta tggcggccgt
     4261 tgaaaatcca cgaatagcgg ttgcagcact taatcctcat gccggtgatg gaggaacctg
     4321 tggtaaggaa gaaattgatg ttctcattcc ggtcattgaa ggcttccgcg agaaagggat
     4381 ggatatgtat ggcccagtac cgggtgatac tgtttttatt catgcattta atcatgaata
     4441 tgatgctgtc gttaccctgt tccatgacca gggacagatt gccaccaagc ttcattcctt
     4501 tgatgtgggc ataactgtag ccgcagggct tccatttgct attacaacac cggaacatgg
     4561 cactgcattt gatattgcag gcaagggaat agcaaaaact ctggccacag agcgggctat
     4621 tgcagttgca gctagaatgg catctacagt gcataaagat aattgagatc tctaaatctt
     4681 agtgtattta tatattcttt tttgatttta ttgaatgaag ttatttttat gttattccgc
     4741 cttagccata agccatggtt aaagcggaat aacaagccaa aaagcgtccc
//
LOCUS       DAFGPF010000213         4725 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFGPF010000213 DAFGPF010000000
VERSION     DAFGPF010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4725
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.215"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            39..1955
                     /gene="mngA"
                     /locus_tag="LSX49_005018"
     CDS             39..1955
                     /gene="mngA"
                     /locus_tag="LSX49_005018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBL7171282.1"
                     /translation="MNLTTLTHRDALCLNVRFTSREEAIHALTQRLAALGKISSTEQF
                     LEEVYCRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVV
                     LLAIPPNEAGTTHMKLLTALTTRLADDELRARIQSATTPDELLSALDDKGDAQHTASF
                     SYAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNIYVEKQGANGIEERLTAEQLNS
                     ATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDT
                     QPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMY
                     RKLGGGMLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAG
                     YLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNG
                     LSGNNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFT
                     VTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTG
                     AIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRHH
                     AVKHGNYLTDGVMP"
     gene            1973..4606
                     /gene="mngB"
                     /locus_tag="LSX49_005019"
     CDS             1973..4606
                     /gene="mngB"
                     /locus_tag="LSX49_005019"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBL7171283.1"
                     /translation="MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQD
                     NEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEGGKLIIGPWYTQTDTTIVSAESIV
                     RNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
                     TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLP
                     NGHDQMPLQQNIFEVMEKLREIYPQRKFVMSRFEEVFEQIEAQRESLAILKGEFIDGK
                     YMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFDYHHGLLEKMWKEILK
                     NHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNL
                     MPWPREEVINTTVRLRGSQFNLRDGRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPF
                     MEFDIQISQIVPSMGYRTLYIEANQLGNVVTPKSKTEGILENAFWQIALNEDGSLRLV
                     DKDSGVRYDRVFQIEEGSDDGDEYDYSPAKEEWAITSANAKPQYDIIHEAWQSRAIIR
                     YEIAVPRNLSERRAKQCSGRVGVETVITLSHNSRRIDADINLDNQADDHRIRVLIPTP
                     FNTDVVLADTQFGSLTRPVKDCAMNVWQQEGWKEAPVPVWNMLNYAVLQEGRNGIAVF
                     SEGLREFEVIGEENKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVSDSQLRGSFSC
                     RLSLFSYIGTPVTAGVAQQARAWLTPVQCYNKIPWDAMKLNKAKFNVPESYSLLKMPP
                     VGCLISALKKAEDRQELILRLFNPAELTSCDATVAFSRKVMTCTETMMNERFNTEKNE
                     VLKELALFLPGQSRTFSYRIV"
BASE COUNT         1188 a         1054 c         1297 g         1186 t
ORIGIN      
        1 acttgcgcga ctataaaaat gatcaagtga gaaccatgat gaacctgacg actctgaccc
       61 accgcgatgc gctgtgtctg aatgtgcgct ttaccagccg tgaagaggcc atccacgcgt
      121 tgactcaacg tcttgctgct ctggggaaaa tttccagtac tgagcaattt ctggaagaag
      181 tgtattgccg tgaaagcctc ggcccgaccg ccttaggtga agggctggcc gtgccgcatg
      241 gcaaaactgc tgcggtaaaa gaagcggcgt ttgcggtcgc cacactcagc gagccgcttc
      301 agtgggaagg cgtggatggc ccggaagcgg ttgatttagt ggtattgctg gccattcctc
      361 ccaatgaagc aggtactacg catatgaaac tgcttaccgc gctgaccacg cgcctggcgg
      421 atgatgagct cagggcgcgt attcagtcgg caacgacgcc cgatgaattg ctctcggcgc
      481 tggatgacaa gggggacgcg caacatactg cctctttttc ttatgcgcca actatcgtct
      541 gcgtaacggc ctgcccggcg ggtattgctc acacctacat ggctgcggaa tatctggaaa
      601 aagccggacg caaactcggc gtgaatatct acgttgaaaa gcaaggtgct aacggcattg
      661 aagagcgttt aacggcggag caactcaata gtgcaaccgc ctgtattttt gcggcggaag
      721 tcgctatcaa ggagagcgag cgttttaacg gcattcccgc gctttctgtg cctgttgccg
      781 agccgattcg ccatgcagaa gcgttgattc aacaagcgct taccctcaag cgtagcgatg
      841 agacgcgtac cgtacagcaa gatacgcaac cggtgaaaag tgtcaaaacg gagctgaagc
      901 aggcactgtt gagcgggatc tctttcgccg tgccgctgat tgtcgcgggt ggcacggtgc
      961 tggcggtcgc ggtattactg tcgcaaatct tcgggctaca agatttgttt aatgaagaaa
     1021 actcctggtt gtggatgtac cgcaagctgg gcggcgggat gctcgggatt ttgatggtac
     1081 cggtgctcgc agcctatacc gcctattcac tggctgataa accggcgtta gcgccaggct
     1141 ttgcggcagg gcttgccgcc aacatgattg gttccgggtt tctcggcgcg gtcgttggcg
     1201 gattgatagc cggttatctg atgcgctggg tgaaaaatca tctacgtctt agcagtaaat
     1261 tcaacggatt cctgactttc tatctctacc cggtgctcgg tacgttgggg gcgggtagtc
     1321 tgatgctgtt tgtagtaggg gaacctgtcg catggatcaa taactcgctt accgcctggc
     1381 tgaacggtct gtcaggaaat aacgcactgt tgttgggcgc cattctcggt tttatgtgtt
     1441 cctttgacct tggtgggcca gtgaacaaag ccgcttatgc attctgtctg ggggcaatgg
     1501 cgaacggcgt ttacggcccg tatgccattt tcgcctccgt caaaatggtt tcggcattta
     1561 ccgtaaccgc ttccacgatg ctcgcaccgc gcctgtttaa agagtttgaa attgaaaccg
     1621 ggaaatccac ctggctgtta ggattggcag gtatcaccga aggggcgatc ccgatggcga
     1681 ttgaagatcc gctgcgggtt attggttcgt ttgtgctggg atctatggta acgggcgcta
     1741 tcgtcggtgc gatgaatatc ggcctttcga cacccggtgc cggcattttc tcgctctttt
     1801 tacttcatga taatggcgcg ggtggtgtta tggcggcaat tggttggttt ggtgcggcgt
     1861 tggtgggggc tgcaatctcg actgcaattc tcctgatctg gcggcatcat gcggtaaagc
     1921 atggaaacta tctgactgat ggcgtaatgc cataaacaaa aaggaaacga cgatgaaagc
     1981 ggtatctcgc gttcacatca ccccgcatat gcactgggat cgggagtggt atttcaccac
     2041 agaagagtct cgcattctgc tggtcaataa tatggaagag atcctgtgca gactggaaca
     2101 ggacaacgaa tacaaatatt acgtactcga cgggcaaacg gcgatcctcg aagattattt
     2161 cgctgtcaaa ccggagaaca aagatcgtgt gaagaagttg gtcgagggcg ggaaattaat
     2221 tatcggtccc tggtataccc agaccgatac cacgattgtt tctgctgaat ccatagtccg
     2281 taatctgatg tacggaatgc gtgactgcct cgcgtttggc gagccgatga aaataggtta
     2341 tttaccggat tcctttggca tgtccgggca actgccacat atatacaatg gatttggcat
     2401 tacccgcacc atgttctggc gcggatgttc tgagcgccac ggtactgata aaaccgagtt
     2461 tttgtggcaa agcagtgacg gtagcgaagt gacggcgcag gtgctgccgc tgggctacgc
     2521 catcggtaag tacttacctg cggacgaaaa tggattacgt aaacgcctcg acagttattt
     2581 tgacgtgctg gaaaaagcgt cagtaaccaa agaaatttta ttgccgaatg gtcatgacca
     2641 gatgcccttg cagcaaaata tcttcgaagt gatggagaaa ctgcgcgaaa tttatcctca
     2701 acgaaagttt gtgatgagcc gctttgaaga ggtattcgag cagattgaag cgcagcgtga
     2761 aagtctggcc atcctgaaag gtgaattcat cgatggcaaa tatatgcgcg tgcatcgcac
     2821 catcggttcc acgcgcatgg atatcaaaat tgcccacgca cgcattgaaa ataagattgt
     2881 taatctgctg gaaccgttgg caacgctggc ctggacttta ggttttgatt atcaccacgg
     2941 cttgctggag aagatgtgga aagaaatttt aaaaaaccac gcccatgaca gcatcggctg
     3001 ctgctgcagt gataaagttc atcgcgagat tgtcgcccgc ttcgaactgg cagaagacat
     3061 ggcggataat ctaattcggt tctatatgcg caaaatagca gacaacatgc cgcagagcga
     3121 cgccgacaaa ctcgtcctgt ttaacctgat gccctggccg cgtgaagaag ttatcaacac
     3181 aactgttcga ctgcgcggta gccagtttaa tttgcgagac ggtcgcggtc agcctgtgcc
     3241 atattttatt cgacatgccc gtgagatcga tcccggcctt attgatcggc aaatagttca
     3301 ttacggcaat tatgatccct ttatggagtt tgatattcag atcagccaaa ttgtcccttc
     3361 tatggggtat cgcacgctct atatagaagc gaatcagctt ggcaatgtgg tcacgccaaa
     3421 aagtaaaaca gagggaatac tggaaaatgc tttctggcaa attgcactca atgaggatgg
     3481 ttcacttcgt ctggttgata aagatagtgg cgtgcgctat gaccgggtgt ttcaaattga
     3541 agaaggttcc gatgatgggg atgaatatga ttattcgcca gcaaaagaag agtgggccat
     3601 tacctcagcg aatgcgaaac cgcaatacga tattattcat gaagcctggc agagtagggc
     3661 cataattcgc tatgaaatag cggtgccgcg taatctgtca gagcgtcgcg caaagcaatg
     3721 ttctggcagg gtaggggtgg agacggtgat cactcttagc cataacagca gacgcattga
     3781 tgcggatatt aatcttgata accaggccga tgatcaccgt attcgtgtat tgattcccac
     3841 gccttttaac acagatgttg ttcttgcgga tacgcagttt ggttcattga cgcggccagt
     3901 gaaggattgc gcaatgaatg tctggcagca agaaggctgg aaagaagcgc cggttccggt
     3961 atggaatatg ctcaactatg ctgtcttaca ggaagggcgt aacggcatag ccgtttttag
     4021 cgaaggatta cgtgaatttg aagtcattgg agaagagaat aaaacctttg ctattacgtt
     4081 gttgcgtggt gtgggattac tgggaaaaga agatttactt ttaaggccag ggcgtccttc
     4141 aggaattaaa atgcctgtgt ccgattcaca attacgcgga tcattttcct gtcgtctgag
     4201 tttatttagt tatatcggta ctcccgtaac tgccggtgta gcccagcagg cacgcgcatg
     4261 gctgacgcca gttcagtgtt ataacaaaat cccgtgggat gcgatgaagc ttaataaagc
     4321 caaattcaat gtgccggaaa gctatagttt gctgaaaatg ccaccagtgg gatgtctgat
     4381 cagcgcgcta aaaaaagcag aagacagaca ggaattaata ttgcggctgt ttaatccggc
     4441 tgaattgaca agctgtgatg cgaccgtcgc gtttagcagg aaggtgatga cgtgtacaga
     4501 aaccatgatg aatgaacgct ttaatacaga aaaaaatgag gttttaaaag aattagctct
     4561 ctttttaccg ggacagtcgc ggacatttag ctaccgaata gtctgaatgg tgtgtaataa
     4621 agcaaaccac atgaaaaaac agcgtttctc agaaagttca ggtcatctcc ggatggcctt
     4681 tttgtttcaa ggtgagtggg tgttaatctg aaaagtgtac ttatt
//
LOCUS       DAFGPF010000214         4678 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFGPF010000214 DAFGPF010000000
VERSION     DAFGPF010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4678
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.216"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..2917
                     /gene="sat"
                     /locus_tag="LSX49_005020"
     CDS             <1..2917
                     /gene="sat"
                     /locus_tag="LSX49_005020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="serine protease autotransporter toxin Sat"
                     /protein_id="HBL7171284.1"
                     /translation="LHQNNADTTGTQEKITKDKDIVFTNGGNVLFKDNLDFGSGGIIF
                     DEGHEYNINGQGFTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKKQGANI
                     KIGEGNVILNEEGTFNNIYLASGNGKVILNKDNSLGNDQYAGIFFTKRGGTLDLNGHN
                     QTFTRIAATDDGTTITNSDTTKEAVLAINNEDSYIYHGNINGNIKLTHNINSQDKKTN
                     AKLILDGSVNTKNDVEVSNASLTMQGHATEHAIFRSTANHCSLVFLCGTDWVTVLKET
                     ESSYNKKFNSDHKSNNQQTSFDQPDWKTGVFKFDTLHLNNADFSISRNANVEGNISAN
                     KSAITIGDKNAYIDNLAGKNITNNGFDFKQTISTNLSIGETKFTGGITAHNSQIAIGD
                     QAVVTLNGATFLNNTPISIDKGAKVIAQNSMFTTKGIDISGELTMMGIPEQNSKTVTP
                     GLHYAADGFRLSGGNANFIARNMASVTGNIYADDAATITLGQPETETPTISSAYQAWA
                     ETLLYGFDTAYRGAITAPKATVSMNNAIWHLNSQSSINRLETKDSMVRFTGDNGKFTT
                     LTVDNLTIDDSAFVLRANLAQADQLVVNKSLSGKNNLLLVDFIEKNGNSNGLNIDLVS
                     APKGTAVDVFKATTRSIGFSDVTPVIEQKNDTDKATWTLIGYKSVANADAAKKATLLM
                     SGGYKAFLAEVNNLNKRMGDLRDINGESGAWARIMSGTGSAGGGFSDNYTHVQVGADN
                     KHELDGLDLFTGVTMTYTDSHAGSDAFSGETKSVGAGLYASAMFESGAYIDLIGKYVH
                     HDNEYTATFAGLGTRDYSSHSWYAGAEVGYRYHVTDSAWIEPQAELVYGAVSGKQFSW
                     KDQGMNLTMKDKDFNPLIGRTGVDVGKSFSGKDWKVTARAGLGYQFDLFANGETVLRD
                     ASGEKRIKGEKDGRMLMNVGLNAEIRDNLRFGLEFEKSAFGKYNVDNAINANFRYSF"
     gene            3189..3449
                     /locus_tag="LSX49_005021"
                     /pseudo
     CDS             3189..3449
                     /locus_tag="LSX49_005021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3514..4665
                     /locus_tag="LSX49_005022"
     CDS             3514..4665
                     /locus_tag="LSX49_005022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS30 family transposase"
                     /protein_id="HBL7171285.1"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDT
                     GGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRR
                     YYKAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQK
                     TLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPI
                     HERSRNIDNRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQALT
                     DKFLSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIR
                     QYFPKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
BASE COUNT         1491 a          985 c         1059 g         1143 t
ORIGIN      
        1 attacaccaa aacaatgcag ataccactgg tactcaagaa aaaataacta aagacaaaga
       61 tattgtgttc acaaatgggg gaaatgtcct gtttaaggat aatttggatt ttggtagcgg
      121 tggtattatc tttgacgaag gccatgaata taacataaac ggtcagggat ttacatttaa
      181 aggagcagga attgatatcg gaaaagaaag cattgtaaac tggaatgcat tgtattccag
      241 tgatgatgtt ttacacaaaa taggccccgg tactctgaat gttcaaaaaa aacagggggc
      301 aaatataaag ataggtgaag gaaatgttat tcttaatgaa gaaggaacat ttaacaatat
      361 ataccttgca agcggaaatg gtaaggtaat actaaataaa gataattccc ttggcaatga
      421 tcaatatgcg gggatatttt ttactaaacg tggtggcacg ctagatttaa atggacacaa
      481 tcagactttt actagaattg ccgccactga cgatggaaca acaataacta actcagatac
      541 aacgaaagaa gccgttctgg caatcaataa cgaagactcc tacatatatc atgggaacat
      601 aaatggcaat ataaaactaa cgcacaatat taattctcag gataagaaaa ctaatgcaaa
      661 attaattctg gatggtagtg tcaacacaaa aaatgatgtt gaagtcagta atgccagtct
      721 taccatgcaa ggccatgcaa cagagcatgc aatattcaga agcacagcga atcattgctc
      781 cctggtattt ctttgtggaa cggactgggt caccgttttg aaagaaacag agagttcata
      841 taataaaaag ttcaattctg atcacaaaag taataatcag cagacctcat ttgatcagcc
      901 agactggaaa accggggtgt ttaaatttga tacattacac ctgaacaatg ctgacttttc
      961 aatatcacgc aatgccaatg ttgaaggaaa tatatcagca aataaatcag ctatcacaat
     1021 cggcgataaa aatgcttaca ttgataatct tgcagggaaa aatattacta ataatggttt
     1081 tgacttcaaa caaactatca gtactaatct atccatagga gaaactaaat ttacaggtgg
     1141 catcactgca cataacagcc aaatagccat aggtgatcaa gctgtagtta cacttaatgg
     1201 tgcaaccttt ctgaataata ctcctataag tatagataaa ggagcaaaag ttatagcaca
     1261 aaattccatg ttcacaacaa aaggtattga tatctccggt gagctgacta tgatgggaat
     1321 ccctgaacag aatagtaaaa ctgtaacgcc gggtctccac tacgctgctg atggattcag
     1381 gctgagtggt ggaaatgcaa atttcattgc cagaaatatg gcatctgtca ccggaaatat
     1441 ttatgctgat gatgcagcaa ccattactct gggacagcct gaaactgaaa caccgactat
     1501 atcgtctgct tatcaggcat gggcagagac tcttttgtat ggctttgata ccgcctatcg
     1561 aggcgcaata acagccccca aagctacagt tagcatgaat aatgcgatct ggcatctaaa
     1621 tagccagtca tcaattaatc gtctagaaac aaaagacagt atggtgcgtt ttactggtga
     1681 taatgggaag tttacaaccc ttacagtgga caaccttact atagatgaca gtgcatttgt
     1741 gctgcgtgca aatctggccc aagcagatca gcttgttgtc aataaatcgt tgtctggtaa
     1801 aaacaacctt ctgttagtcg acttcattga gaaaaatgga aacagcaacg gactgaatat
     1861 cgatctggtc agcgcaccaa aaggaactgc agtagatgtc tttaaagcta cgactcggag
     1921 tattggcttc agtgatgtaa caccggttat cgagcaaaag aacgatacag acaaagcaac
     1981 atggactctg atcggctata aatctgtggc caacgccgat gcggctaaaa aggcaacatt
     2041 actgatgtca ggcggctata aagccttcct tgctgaggtc aacaacctta acaaacgtat
     2101 gggtgatctg cgtgacatta acggtgagtc cggtgcatgg gcccgaatca tgagcggaac
     2161 cgggtctgcc ggcggtggat tcagtgacaa ctacacccac gttcaggtcg gtgcggataa
     2221 caaacatgaa ctcgatggcc ttgacctctt caccggggtg accatgacct ataccgacag
     2281 ccatgcaggc agtgatgcct tcagtggtga aacgaagtct gtgggtgccg gtctctatgc
     2341 ctctgccatg tttgagtccg gagcatatat cgacctcatc ggtaagtacg ttcaccatga
     2401 caacgagtat accgcaactt tcgccggcct tggcaccaga gactacagct cccactcctg
     2461 gtatgccggt gcggaagtcg gttaccgtta ccatgtaact gactctgcat ggattgagcc
     2521 gcaggcggaa cttgtttacg gtgctgtatc cgggaaacag ttctcctgga aggaccaggg
     2581 aatgaacctc accatgaagg ataaggactt taatccgctg attgggcgta ccggtgttga
     2641 tgtgggtaaa tccttctcgg gtaaggactg gaaagtcaca gcccgcgccg gccttggcta
     2701 ccagtttgac ctgtttgcca acggtgaaac cgtactgcgt gatgcgtccg gtgagaaacg
     2761 tatcaaaggt gaaaaagacg gtcgtatgct catgaatgtt ggtctcaacg ctgaaattcg
     2821 cgataatctt cgcttcggtc ttgagtttga gaaatcggca tttggtaaat acaacgtgga
     2881 taacgcgatc aacgccaact tccgttactc tttctgataa cagcccgggc cgcgtttgcg
     2941 gcccttcttc taccggagag aatatgtatt accctgtgac agactatatc gctcttgctc
     3001 tcattattag ctttcttttt ctgacattat ttatctgcct gttatgcctt aaacatgagc
     3061 gaataaaaaa agaaactatc aggcaaaaaa atgcacatat tctggatcat ggctggaatg
     3121 caactgaggt agcctgagtt taacggacac tccttcctga aatagaatgg catcagaagg
     3181 agctaataat gagcagaaaa acccaacgtt actctaaaga gttcaaagcc gaagctgtca
     3241 gaacggttct tgaaaatcaa ctttcgatca gtgaaggcgc ttcccgatta tctcttcctg
     3301 aaggcacttt aggacaatgg gttaccgccg ccagaaaagg gctcggtact cctggttccc
     3361 gcacggtggc tgaactggaa tctgaaattc tgcaactgcg taaggcgtta aatgaagctc
     3421 gccttgagcg agatatatta aaaaaagcaa ctgtagattc aattggtcaa cgcaacagtt
     3481 atgtgaaaac atggggttgc ggaggttttt tgaatgagac gaacatttac agcagaggaa
     3541 aaagcctctg tttttgaact atggaagaac ggaacaggct tcagtgaaat agcgaatatc
     3601 ctgggttcaa aacccggaac gatcttcact atgttaaggg atactggcgg cataaaaccc
     3661 catgagcgta agcgggctgt agctcacctg acactgtctg agcgcgagga gatacgagct
     3721 ggtttgtcag ccaaaatgag cattcgtgcg atagctactg cgctgaatcg cagtccttcg
     3781 acgatctcac gtgaagttca gcgtaatcgg ggcagacgct attacaaagc tgttgatgct
     3841 aataaccgag ccaacagaat ggcgaaaagg ccaaaaccgt gcttactgga tcaaaattta
     3901 ccattgcgaa agcttgttct ggaaaagctg gagatgaaat ggtctccaga gcaaatatca
     3961 ggatggttaa ggcgaacaaa accacgtcaa aaaacgctgc gaatatcacc tgagacaatt
     4021 tataaaacgc tgtactttcg tagccgtgaa gcgctacacc acctgaatat acagcatctg
     4081 cgacggtcgc atagccttcg ccatggcagg cgtcataccc gcaaaggcga aagaggtacg
     4141 attaacatag tgaacggaac accaattcac gaacgttccc gaaatatcga taacagacgc
     4201 tctctgggac attgggaggg cgatttagtc tcaggtacaa aaaactctca tatagccaca
     4261 cttgtagacc gaaaatcacg ttatacgatc atccttagac tcaggggcaa agattctgtc
     4321 tcagtaaatc aggctcttac cgacaaattc ctgagtttac cgtcagaact cagaaaatca
     4381 ctgacatggg acagaggaat ggaactggcc agacatctag aatttactgt cagcaccggc
     4441 gttaaagttt acttctgcga tcctcagagt ccttggcagc ggggaacaaa tgagaacaca
     4501 aatgggctaa ttcggcagta ctttcctaaa aagacatgtc ttgcccaata tactcaacat
     4561 gaactagatc tggttgctgc tcagctaaac aacagaccga gaaagacact gaagttcaaa
     4621 acaccgaaag agataattga aaggggtgtt gcattgacag attgaatcta caaccgcg
//
LOCUS       DAFGPF010000215         4660 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.217, whole genome shotgun sequence.
ACCESSION   DAFGPF010000215 DAFGPF010000000
VERSION     DAFGPF010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4660
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.217"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            111..1793
                     /locus_tag="LSX49_005023"
     CDS             111..1793
                     /locus_tag="LSX49_005023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310130.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HBL7171286.1"
                     /translation="MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAF
                     SDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAI
                     EAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGI
                     PLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQ
                     NRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPF
                     MLYLAYNAPHLPNDNPAPEQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQ
                     YDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKL
                     ISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQNKKQGEPHKNLTWITSYSHWFDEE
                     NIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTD
                     LQQKDNLAAANPQVVKEMQGVVREFIDNSQPPLSEVNQEKFNNIKKALSEAK"
     gene            1845..3002
                     /locus_tag="LSX49_005024"
     CDS             1845..3002
                     /locus_tag="LSX49_005024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HBL7171287.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQIEFNTLTVI
                     NNINVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRISAKCQQCVYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN"
     gene            3014..3925
                     /locus_tag="LSX49_005025"
                     /pseudo
     CDS             3014..3925
                     /locus_tag="LSX49_005025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416011.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
     gene            4287..>4660
                     /locus_tag="LSX49_005026"
     CDS             4287..>4660
                     /locus_tag="LSX49_005026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBL7171288.1"
                     /translation="MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIG"
BASE COUNT         1433 a         1004 c          946 g         1277 t
ORIGIN      
        1 tttttttagc taaatctgct atctctttat gtgactaact tcacttacat tcacttattt
       61 ctcttcgtaa aattactttg gaattaagta caataagaag aggaacattt atgaagtctg
      121 cattaaagaa aagtgtcgta agtacctcga tatctttgat actggcatct ggtatggctg
      181 catttgctgc tcatgcggca gatgatgtaa agctgaaagc aaccaaaaca aacgttgcgt
      241 tctcagactt tacgccgact gaatacagta ccaaaggaaa gccaaatatt atcgtactga
      301 ccatggatga tcttggttat ggacaacttc cttttgataa gggatctttt gacccaaaaa
      361 caatggaaaa tcgtgaagtt gtcgatacct acaaaatagg gatagataaa gccattgaag
      421 ctgcgcaaaa atcaacgccg acgctccttt cattaatgga tgaaggcgta cgttttacta
      481 acggctatgt ggcgcacggt gtttccggcc cctcccgcgc cgcaataatg accggtcgag
      541 cgcccgcccg ctttggtgtc tattccaata ctgatgctca ggatggtatt ccgctaacag
      601 aaactttctt gcctgaatta ttccagaatc atggttatta cactgcagca gtaggtaaat
      661 ggcacttatc aaaaatcagt aatgtgccgg tgccggaaga taaacaaacg cgtgactatc
      721 atgacaactt cactaccttt tctgcggaag aatggcaacc gcaaaaccgt ggctttgatt
      781 actttatggg attccatgct gcaggaacgg catattacaa ctccccttca ctgttcaaaa
      841 accgtgaacg cgtccccgca aaaggttata tcagcgatca gttaaccgat gaagcaattg
      901 gcgttgttga tcgtgccaaa acacttgacc agccttttat gctttacctg gcttataatg
      961 ctccgcacct gccaaatgat aatcctgctc cggagcaata tcagaagcaa tttaataccg
     1021 gtagtcaaac agcagataat tactacgctt ccgtttattc tgttgatcag ggtgtaaaac
     1081 gcattctcga acaactgaag aaaaacggac agtatgacaa tacaattatt ctctttacct
     1141 ccgataatgg tgcagttatc gatggtcctc tgccgctgaa cggggcgcaa aaaggctata
     1201 agagtcagac ctatcctggc ggtactcaca ccccaatgtt tatgtggtgg aaaggaaaac
     1261 ttcaacccgg taattatgac aagctgattt ccgcaatgga tttctacccg acagctcttg
     1321 atgcagccga tatcagcatt ccaaaagacc ttaagctgga tggcgtttcc ttgctgccct
     1381 ggttgcaaaa taagaaacaa ggcgagccac ataaaaatct gacctggata acatcttatt
     1441 ctcactggtt tgatgaggaa aatattccat tctgggataa ttaccacaaa tttgtccgcc
     1501 atcagtcaga cgattacccg cataacccca acaccgagga cttaagccaa ttctcttata
     1561 cggtgagaaa taacgattat tcgcttgtct atacagtaga aaataatcag ttaggtctat
     1621 acaaactgac ggatctacag caaaaagata accttgccgc cgccaatccg caggtcgtta
     1681 aagagatgca aggcgtggta agagagttta tcgataacag ccagccaccg cttagcgagg
     1741 taaatcagga gaagtttaac aatatcaaga aagcactaag cgaagcgaaa taactaaacc
     1801 tttatgcggc ggatttttcc gccgccttat tgagcgagat agcgatgcac gttacagcca
     1861 agccctccag ttttcaatgt aatctcaaat gtgattactg tttttacctt gaaaaagagt
     1921 cgcagtttac tcatgaaaaa tggatggatg acagcactct gaaagagttc atcaaacaat
     1981 atatcgcagc gtctggcaat caggtctatt ttacctggca aggcggtgaa cccactctgg
     2041 ctggcctgga ttttttccgt aaagttattc actatcaaca acgctatgca ggccaaaaac
     2101 gtatttttaa tgcattacaa acgaatggca ttttattgaa taatgaatgg tgtgcctttc
     2161 tcaaagaaca tgagtttctg gttggtatct cgatcgatgg cccccaagaa ctacatgacc
     2221 gttacagacg cagtaattca ggtaacggta cttttgcaaa agtgatagca gccatcgagc
     2281 gtctgaaatc atatcaaata gagtttaata cgttaaccgt tattaataac attaatgtcc
     2341 attaccctct tgaggtttat cattttttaa aatctatcgg cagtaaacat atgcaattta
     2401 tcgaattgct cgaaaccggg acgccgaata ttgatttcag tggtcatagt gagaacacat
     2461 tccgtatcat tgatttttct gtgcctccca cggcttatgg caagtttatg tcaaccattt
     2521 ttatgcaatg ggttaaaaac gatgtgggtg aaattttcat ccgtcagttt gaaagctttg
     2581 tcagccgttt tttggggaat gggcatacca gttgtatttt ccaggagtcc tgcaaggata
     2641 atctggttgt tgaaagtaat ggagacattt acgaatgcga ccattttgtc tatccacagt
     2701 acaaaattgg aaacattaat aaatcggaac tcaaaacgat gaacagtgta caactgacag
     2761 cgcaaaaaaa acggatttca gcgaaatgtc agcaatgtgt atataaacct atctgcaatg
     2821 gtggttgccc taagcatcgt attactaaag taaacaatga gactgtttcc tatttttgcg
     2881 aaggttataa aatccttttt tcaaccatgg taccttatat gaacgccatg gtggagttag
     2941 ctaagaacag agtaccgctt taccacatta tggatgttgc aaaacaaatg gagaataatt
     3001 aataacgctc ccccacagca cgattaacga caatatttgg gcatcgctac aaaatgctca
     3061 aattcaggcg ttgaaaacgc tcgaccagcg tccagcggag aaattcgccc agcagatgta
     3121 tgagacgcgc tatgctgata accgcacgaa attaccgcaa gcaaatcaga ttgcacagtt
     3181 tactgccgca gatgcactgg ctgccgatcg ccagttgttt tcatctccag cggatatcac
     3241 gtttgtcatt gtcggtaatg tcgcagaaga caaactcgtg gcgttaatta cgcgttactt
     3301 aggatcaatc aaacactctg attcgccatt agccgcaggt aaaccattaa ctcgcgcgac
     3361 ggacaacgca tcggttactg taaaagaaca aaatgaacca gtggcacagg tttcacagtg
     3421 gaagcgttat aattcccgga ctcctgttaa tctggcgacg cgtatggcgc tcgatgcttt
     3481 taacgtcgca ctggcaaaag atctacgcat taatattcgt gaacaggcat ccggggcata
     3541 cagcgtttct tctcgcctct cggttgatcc tcaggccaaa gatatcagtc atttgctggc
     3601 ttttacttgt caaccagaac gacatgatga actgttaacg ttagcgaatg aagtgatggt
     3661 taagcgtctg gccaaaggga tcagtgagca agaactgaac gaataccagc aaaacgttca
     3721 gcgcagcctc gatatccaac agcgtagcgt tcaacaatta gcgaacacca ttgtaaatag
     3781 tcttattcaa tatgacgatc ctgcagcatg gactgagcag gagcaattgt tgaaacaaat
     3841 gacggtagag aatgttaaca ctgctgttaa acaatatctt tctcatccgg tgaataccta
     3901 taccggagta ttattgccaa aataatcaca gccccgtcaa cacatcgttg gcggggattt
     3961 catcaatatt cgctattttt atgtaataat tttataaatg tgttcaaagt aaataaccgt
     4021 gtaccaataa tgatattata aggtctgatt tttacgtgat aattcaggag acgatagaaa
     4081 acacataaaa taacagcata aaacacctta cctccacaca gaattctcta ttatgttgtt
     4141 ttttaataaa aatacattat tcacgcaata tctcgcgata aataacatta ggattttgtt
     4201 atttaaaacc gagtcctttg cacttgctta ctttatcgat aaatcctact tttttaatgc
     4261 gatccaatca ttttaaggag tttaaaatgg ataagaagca agtaacggat ttaaggtcgg
     4321 aactactcga ttcacgtttt ggtgcgaagt ctatttccac tatcgcagaa tcaaaacgtt
     4381 ttccgctgca cgaaatgcgt gatgatgtcg cattccagat tatcaatgac gaattatatc
     4441 ttgatggcaa cgctcgtcag aacctggcca ctttctgcca gacctgggac gacgaaaatg
     4501 tccataagtt gatggattta tccattaaca aaaactggat cgacaaagaa gaatatccgc
     4561 aatctgcagc aatcgatctg cgttgcgtaa acatggttgc cgatctgtgg catgcgcctg
     4621 caccgaaaaa tggtcaggcc gttggcacca acaccattgg
//
LOCUS       DAFGPF010000216         4537 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFGPF010000216 DAFGPF010000000
VERSION     DAFGPF010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4537
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.218"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(365..1593)
                     /locus_tag="LSX49_005027"
     CDS             complement(join(365..1278,1278..1593))
                     /locus_tag="LSX49_005027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL7171289.1"
                     /translation="MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAAS
                     QLFLWRKQYQEGSLTAVAAGEQVIPASELAAAMKQIKELQRLLGKKTMENELLKEAVE
                     YGRGKKVDSARALIARGWGVSFVSRCLRVSRAQLHVILRRADDWKDGRRSRHTDDTDV
                     LRRIHHVIGELPTYGYRRVWALLRRQTELDGMPAINAKRVYRTMRQNALLLERKPAVP
                     PSKRAHTGRVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHWAVTTGGFD
                     SETVQDVMLGAVERRFGSELPASPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRS
                     PESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREY
                     LRQWASDGLSDNRCLEI"
     gene            complement(1745..2731)
                     /locus_tag="LSX49_005028"
     CDS             complement(1745..2731)
                     /locus_tag="LSX49_005028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171290.1"
                     /translation="MYHHDFNEKIGFWYVIALAGQSNGMAYGEGIPLPDTLDKPESRV
                     KQLARRKTITPGGKECKFNEIIPADHCLHDVQDMSGYHHPAADLHKGEYGCVGQGLHI
                     AKKLLPYIPEQAGILLVPCCRGGAAFTVGAEGMYVPDTGATADAMRWGTGTALYEDLV
                     ARVKVALEYNRKNKLLSVCWMQGEFDLMSPDYEKHPDLFYQMVTSFRSELSEYSSQCV
                     GNSSERVPWLCGDTTWYWKESYQKEYDFIYGHYRQRTDDEIHFLSFQDSNRHELTNEP
                     EEDADDLSVGYLGSSWRTELSWTTSQRSTHFNSMARRGVIAECYAQKIRNYL"
     gene            2831..3565
                     /gene="nanR"
                     /locus_tag="LSX49_005029"
     CDS             2831..3565
                     /gene="nanR"
                     /locus_tag="LSX49_005029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HBL7171291.1"
                     /translation="MSDNKKTVLPGLTTTRKPIVTKKLSEIVAEELERMIRQEEIREG
                     EYLPSERELMAFFGVGRPSVREALSSLRHKGLIRYNKGEKASVCRPSPETIINGLSGI
                     VKDFLSTADGIKDFERLRIFFETNLVRYAAKNATPEDIHRLEKVLSIHHNSLRTPEVY
                     AQYDIEFHSILADIPDNKVLKTIHSAFSEWLIMAKPLEKNKMTYENNKKTHQQHIEIL
                     TAIKEHDCDKAEQLMYNHLYKRIEAS"
     gene            complement(3601..4536)
                     /locus_tag="LSX49_005030"
     CDS             complement(3601..4536)
                     /locus_tag="LSX49_005030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001305022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL7171292.1"
                     /translation="MGFIMNKDRSLNEMMLSLFNKSTIVDLSSETISESKSLSGRIYQ
                     DPEHNGEFELDRVLTDIYAPQLIIFLPDKPNGTGILIIPGGGYQAVMLDKEGTALAPE
                     FLSQGYTLFVLSYRLPSPVEGENINKTFIDAISAMLYIRKNADKWHLQRHRIGVLGFS
                     AGGHIASTFVNQICDFKRSSDSKEQEIFAIPDFVGLIYPVISMKDDVTHPGSRKQLLG
                     DNSTSENIIQYSADLNVTSCFPPVFLLHCCDDDLVSIENSLLMYRGLIEKGVSAEMHL
                     YEKGGHGFSIQWATDLSVGGWIKLFMDWMYSHGFK"
BASE COUNT         1299 a         1096 c          875 g         1267 t
ORIGIN      
        1 tgccagttaa cagctatccg tatggcgtgt tcggttttgc gaataaaaaa tggttactgt
       61 agaagcggat ttccaccaca tgtcaaccat gaatggtcag tggtgcgaga cgactgggat
      121 gatttggtcg atgacttctt ccggcgaata ctgatagaaa cattgaaata ttgtaagaga
      181 aagcgttcaa aattctgtgg cacgtgaaaa attctacagc gtcatcacct tattcagtcg
      241 accttcaaaa taaacgttta acagagacaa tcaccatttg gattgtccgc tgaggaggcg
      301 aacgatttcc tagacagctt tatcatgtca gcccacattg ttggcgctga caatggattt
      361 gcccctatat ttccagacac ctgttatcac ttaacccatc actggcccac tgccgcagat
      421 attcccgtgg cgagcgataa cccagcgcac tatgcggatg ccattcgtta taatgctcga
      481 acgcctctgc aaggttcttt gctgccgtta acccgtctgg tttgggcatg atacttatgt
      541 agtcacgctt tatcgttttc acgaagctct ctgctattcc gttactctcc ggactccgca
      601 ctgccgtgtt cttcggttca agtcccaaca tcctggcgaa ctgacgtgtt tcattcgccc
      661 ggtagcatga accattatcc gtcagccact ccactggaga cgccggaagc tcgctgccaa
      721 agcggcgttc cactgctccc agcatgacgt cctgtactgt ttcactgtcg aagccacccg
      781 ttgtgaccgc ccagtgcagt gcctcacggt cacagcagtc cagcgcgaac gtgacccgca
      841 gtttttctcc gttatcacag cggaactcaa acccgtcaga gcaccatcgc tgattacttt
      901 ctttcacagc cactctgccg gtatgtgccc gtttcgatgg cggtacagcg ggttttcgct
      961 caagcaacag cgcattctgg cgcatggtcc ggtaaacacg tttggcattg atcgcaggca
     1021 taccatcaag ttctgtttgt ctgcgaagca gcgcccatac ccgacgataa ccatatgtgg
     1081 gtagctctcc gataacatgg tgtatacggc gaagcacatc cgtatcatcc gtgtgacggc
     1141 tgcggcggcc gtccttccag tcatcggctc gtctgagaat gacgtgcaac tgcgcacgcg
     1201 acacccggag acaacggctg acgaagctta ctccccatcc ccgggcaata agggcgcgtg
     1261 cgctatccac ttttttgctc gcccatattc aacggcttct ttaaggagtt cattttccat
     1321 cgtttttttg ccgagcagac gctggagttc tttaatctgc ttcatggcgg cagcaagttc
     1381 agaggcagga atgacctgtt ctccggcagc cacagcagta agacttccct cctggtattg
     1441 cttacgccag agaaatagct ggctggctgc cacaccatgt tgccgggcaa caagggagac
     1501 cgtcattccc ggttcaaagc tctgctgaac gatagcgatc ttttcctgtg tagtacgccg
     1561 tctgcgtttc tccggcccta agacatcaat catctgttct ccaatgacta gtctaaaaac
     1621 tagtattaag actatcactt atttaagtga tattggttgt ctggagattc agggggccag
     1681 tctaaccact ccgtcatgtc tctcagagaa tcatgtcaga gctgtagata tatcctgaac
     1741 ttgtctacaa ataatttctt attttttgcg cataacattc agcaataact ccccttctgg
     1801 ccattgaatt aaaatgtgta cttctctgtg acgttgtcca gcttaattct gtcctccatg
     1861 atgaccccag atacccgaca gataaatcat cggcatcttc ttctggctca ttagttaatt
     1921 catgtcggtt actatcctga aagctgagaa aatgtatttc atcatcagtc cgttgtctgt
     1981 aatgtccata tataaaatca tattcttttt gataagattc cttccagtac caggttgtat
     2041 caccacacaa ccatggaact ctttctgacg aattaccaac acactgagat gagtattcag
     2101 ataactcaga cctgaaagaa gttaccatct gataaaacaa gtcaggatgc ttttcataat
     2161 ctggtgacat aagatcaaac tccccctgca tccagcagac agatagcagt ttattctttc
     2221 tgttatattc cagagctacc ttaacccggg ctactaagtc ctcatagagt gctgttccgg
     2281 tgccccaccg cattgcatca gctgttgccc ctgtatcagg tacatacata ccttcagctc
     2341 caacagtaaa ggcggcacct cctctgcaac aaggaaccag taatatccct gcttgctcag
     2401 gtatgtatgg cagtaacttt ttagctatat gcaatccctg tccgacacaa ccatattccc
     2461 ctttatgcaa atcagcagcc ggatggtgat atccactcat atcctgaaca tcatgcaggc
     2521 agtgatctgc cggaataatc tcattgaatt tacactcttt tcctcctggt gtgattgttt
     2581 ttcgacgagc cagttgtttt acacgggact cgggtttgtc gagtgtatct ggcaggggaa
     2641 taccttcacc gtaggccata ccattagact gtcctgcgag ggctatcaca taccagaaac
     2701 ctattttttc attaaaatca tgatgataca tcattccccc tttacataat agatttaatt
     2761 aaatattttc attattaaaa gaaagtgtta aattaaaaac tcatttgctc taatccatat
     2821 aaatcaatat atgtccgaca acaaaaaaac cgtgttaccc gggctaacaa cgaccagaaa
     2881 gcccattgtt acaaaaaaac tttcagaaat cgttgccgaa gagcttgaaa gaatgatccg
     2941 ccaggaggag ataagggaag gtgaatacct gccttctgaa cgtgaactta tggcattctt
     3001 tggcgttgga agaccatctg tcagagaggc tttatcatct ctcagacata aagggctaat
     3061 ccggtataac aagggagaaa aagccagtgt ctgccgtcca tcaccagaaa ccatcattaa
     3121 tgggttatca ggcattgtta aagatttttt atctacagct gatggcatca aggattttga
     3181 aagactacgc atcttttttg aaaccaacct tgtaagatat gcagcaaaaa atgcaacgcc
     3241 tgaggatatt cacaggcttg agaaggtgct cagtatccat cataactcac tgagaacccc
     3301 cgaagtgtat gctcaatatg atattgaatt tcatagtata cttgctgata tacctgacaa
     3361 taaagtatta aaaacaatac actcagcatt ttctgaatgg ctgataatgg ccaaacctct
     3421 ggaaaagaat aaaatgacat atgaaaataa caaaaaaacc catcagcagc atattgaaat
     3481 acttacggcc ataaaagagc atgattgtga taaagctgaa cagctaatgt ataatcacct
     3541 ttataaacga attgaagcat catagttact cgacgcttca ccaggtagtc accataaata
     3601 ttatttaaat ccatgagaat acatccagtc cataaacagt tttatccatc ctccaacaga
     3661 aagatctgtg gcccactgaa tactaaaacc atgccctcct ttctcataga gatgcatttc
     3721 agcagaaacg cctttctcta ttaggccacg gtacatgagc agactgtttt caattgacac
     3781 aagatcatca tcacaacaat ggagtaaaaa cacaggagga aaacatgatg tgacattaag
     3841 atccgcacta tattgtatta tattttctga ggtactattg tcccccagta attgcttcct
     3901 ggagcctgga tgtgtcacat catctttcat tgatattaca ggataaatta acccgacaaa
     3961 atcgggaata gcgaaaatct cttgttcttt actgtcagaa gaacgtttga aatcacaaat
     4021 ctgattcaca aacgttgagg cgatatgccc cccagcagaa aatcctaata caccaatacg
     4081 atgacgctgt agatgccatt tatcagcatt cttacgaata taaagcattg cagatattgc
     4141 atcaataaaa gttttgttta tattttctcc ctcaactggc gatggtaatc tgtaactaag
     4201 aacaaataat gtatagccct gagataaaaa ctctggagca agagctgtac cttccttatc
     4261 taacataaca gcctggtagc cccccccggg aataatcaat attcctgttc catttggttt
     4321 atctggtaaa aaaataatta actgaggagc ataaatatct gtcaatacac gatcaagttc
     4381 aaattccccg ttatgttcag gatcctgata aatacggcct gaaagagatt tactctcaga
     4441 tattgtctca cttgacaagt caacaatagt tgatttatta aacaagctta acatcatttc
     4501 atttaaagat ctatctttat tcattataaa ccccatt
//
LOCUS       DAFGPF010000217         4491 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFGPF010000217 DAFGPF010000000
VERSION     DAFGPF010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4491
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.219"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..434)
                     /locus_tag="LSX49_005031"
     CDS             complement(<1..434)
                     /locus_tag="LSX49_005031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_111779456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytotoxin"
                     /protein_id="HBL7171293.1"
                     /translation="MGNQWQQKYLLEYNELVSNFPSPERVVSDYIKNCFKTDLPWFSR
                     IDPDNAYFICFSQNRSNSRSYTGWDHLGKYKTEVLTLTQAALINIGYRFDVFDDANSS
                     TGIYKTKSADVFNEENEEKMLPSEYLHFLQKCDFAGVYGKTLS"
     gene            complement(712..939)
                     /locus_tag="LSX49_005032"
     CDS             complement(712..939)
                     /locus_tag="LSX49_005032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea transporter"
                     /protein_id="HBL7171294.1"
                     /translation="MGHPEILYFSAISTALSPFFAWCLRYPDEEINEGIWGYNAVLYG
                     IACGMLVPVSVSGIAVLIVGTLEMLLLMGFR"
     gene            complement(1380..2816)
                     /gene="hlyD"
                     /locus_tag="LSX49_005033"
     CDS             complement(1380..2816)
                     /gene="hlyD"
                     /locus_tag="LSX49_005033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000860465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hemolysin T1SS ABC transporter subunit
                     HlyD"
                     /protein_id="HBL7171295.1"
                     /translation="MKTWLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPA
                     HLELIETPVSRRPRLVAYFIMGFLVIAVILSVLGQVEIVATANGKLTLSGRSKEIKPI
                     ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQTRLEQTRYQILSRSI
                     ELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT
                     ILARINRYENLSRVEKSRLDDFRSLLHKQAIAKHAVLEQENKYVEAANELRVYKSQLE
                     QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIELLTLELEKNEERQQASVIRAPV
                     SGKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEA
                     FPYTRYGYLVGKVKNINLDAIEDQKLGLVFNVIVSVEENDLSTGNKHIPLSSGMAVTA
                     EIKTGMRSVISYLLSPLEESVTESLHER"
     gene            complement(2835..>4491)
                     /locus_tag="LSX49_005034"
     CDS             complement(2835..>4491)
                     /locus_tag="LSX49_005034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_063101322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HBL7171296.1"
                     /translation="TLVVSVFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSV
                     VVVFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARVREL
                     DQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYAAWSVFISPILR
                     RRLDDKFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLA
                     TIGQQGIQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVAPVIRLAQIWQ
                     DFQQVGISVTRLGDVLNSPTESYHGKLALPEINGNITFRNIRFRYKPDSPVILDNINL
                     SIKQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVV
                     LQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGL
                     SGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMRNMHKICKGRTVIIIAHRL
                     STVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYLYQLQSD"
BASE COUNT         1357 a         1027 c          779 g         1328 t
ORIGIN      
        1 gacagagttt ttccataaac acctgcaaaa tcacactttt gtaaaaaatg caggtattcc
       61 gacgggagca ttttttcttc attttcttcg ttaaacacat ctgcactctt tgttttataa
      121 attcctgtgc ttgaatttgc atcatcaaaa acatcaaaac gataaccaat attaataaga
      181 gcggcttgag tgagtgtcag tacttctgtt ttatatttcc caagatgatc ccatccagta
      241 taagatctgc tattactccg gttttgagaa aagcagatga aataagcatt atcaggatca
      301 atccgactaa accacggcaa gtcagtttta aaacaattct taatgtaatc gctgacaact
      361 ctttcaggtg aagggaaatt tgataccaac tcattgtact caagaagata tttttgttgc
      421 cattggttac ccataatatt tttaactcct ctgtgaagat taatatttta ctacacctta
      481 tcagaatacc taatcactgg gcgagaggtt agcaatcatg tcgtatacaa agcgtctttg
      541 aaactattta atgaatctta aacatcacta ctccgatccc tgtagtataa attttgcact
      601 acacaacatc ccggtatgca aaaccactgg atttctatta atatattcca cattgaaaga
      661 aagctggtaa acctggcatc accaggacag gtcgggccag caggttaagt attatctgaa
      721 ccccattaaa aggagcatct ccagtgttcc gacaataagt acagcaattc cggagactga
      781 cacagggaca agcatgccac aggctatgcc atacagaaca gcattatatc cccatatacc
      841 ttcattaatc tcctcatcag gataccgcaa acaccaggca aagaacggag aaagtgctgt
      901 actgatggct gagaaataca gtatttcggg gtgccccata ttaaaagagg ctattccagt
      961 tgcaaaaaaa gaacaagcca gaaacaacat tgttctgtaa taatacctgt gaatccccct
     1021 aaccaaagga ggttatcacc tgttttactt tcatgaaaaa tgtcacactc gcctcataca
     1081 tcaaccattc tccgcttctg cgggccagta cctcccctga ctccacctca cagcggattg
     1141 tgtattttta aacaatcaca gtcttctcat atactttcca ttctgaagct tacctcttcc
     1201 tctgtgataa gcttccgtcg cgggatgtgt tatacgccct gtaagacagt tataaaggac
     1261 atcaatgcca tagttaatga ctaccgaatt ccagtggata gtcagtactg gtttgccaca
     1321 aaacagtgca gtcacacatg acaggagaag atatgagccg gataccgcgg ctctgagact
     1381 taacgctcat gtaaactttc tgttacagac tcttccagag gactaagaag atagctgatt
     1441 acgcttcgca ttccagtctt tatttctgca gtgacagcca tacccgagct taatggaatg
     1501 tgcttattcc cggttgacaa atcattctct tcaacagaaa caatgacatt aaaaacgagt
     1561 cccagtttct ggtcttctat tgcatctaaa tttatatttt tcaccttacc caccagataa
     1621 ccatatcggg tgtaaggaaa ggcctccact ttaatgatgg cattctgccc gacgttaata
     1681 aaaccaatat ctttattttg taccagagca gtaacctcca gcgtgtcatc ttccggaacg
     1741 atgaccatca gtgtttccgc tgttgtaaca accccacctt cagtatgaac cttcagttgc
     1801 tgaacttttc ccgaaacagg ggccctgatt actgaagcct gttgacgctc ttcatttttc
     1861 tctaactcca gagttaataa ctcaatgttg tctgttgttt gtcttagctt gtctaaaatt
     1921 tcatttttaa aaagctgcgt gacaagctga tattcttctt ttgcagacaa tatctcactc
     1981 tcaatttgct ccagttgcga tttataaacc cgtaattcat ttgctgcctc gacatattta
     2041 ttctcctgct caagtacagc atgttttgca attgcctgtt tatgcaataa actcctgaaa
     2101 tcatccagac ggcttttttc aactctcgat aaattttcat aacggtttat acgggcaagt
     2161 attgttaatc gctctgctct tttcttatcc agattcagtt ctttttgata cttctgattt
     2221 tgccatgtgg aaaactgttc ttttatcaaa gaagttaaac gcagtacttc ctcttcagat
     2281 acattctgaa aataaggctc atcaggaagc ttcagttcag gtagtttatt taattcaatt
     2341 gacctgctca gaatttgata ccgagtttgt tccagcctgg tctgtaacag tgatgactgt
     2401 gtttttaacg tatcagcttc agctcccagt gctgtaagct ttaataacac atcccctttc
     2461 cggactgact ctccttcttt tacgataatt tctttaacta ttgagttttc aataggttta
     2521 atttctttgc tgcgcccact tagtgttaat ttcccatttg cagtggcaac aatttccacc
     2581 tgacctaaaa cagataaaat gacagcaata accagaaacc ccataataaa ataagcaacc
     2641 agacgcggcc gtctggatac cggcgtttca attaattcca gatgagcggg taagaattca
     2701 ttttcgtcct tttcacgtac cggagtatct aattgcttcc ggattttcca tgtttcactc
     2761 cagacaagtt tatagcgcaa caggaactcg ctgaacccca ttaaccatgt tttcatattc
     2821 ttctgttctt tctgttagtc tgactgtaac tgatataagt aactgtataa actttccggt
     2881 tcagaaagca gttccttatg tttaccctgt tcaacaattt tccctttttc catgacaata
     2941 atgcggtctg cattttttac tgtagacaga cgatgagcaa tgattataac cgttctgccc
     3001 ttacatattt tgtgcatatt gcgcatgatg atatgctccg actcataatc cagagcactg
     3061 gttgcttcat caaaaataag tattttaggg ttgttcacca gcgcccttgc aattgcgatg
     3121 cgttgacgtt gacctccgga taatcctgcc ccctgttccc cgacaatggt gttatacccc
     3181 tcacgcaatt cagaaataaa atcatgagcg cctgctaatt tcgctgcata aataactttt
     3241 tcgacggaca taccaggatt agccagtgag atattatcaa taatactgcg attaagcagc
     3301 acattgtcct gcaacacaac ccccacctga cgacgtaacc agttaggatc ggccaacgca
     3361 agatcatgtc catcaattaa gacctggcca ttttcaggaa tataaaaacg ttgaattaat
     3421 ttagttaatg tgctttttcc tgaaccagaa cgtccgacaa taccaataac ctccccctgc
     3481 ttaatactga gattgatatt atctaaaata accggagagt caggcttata gcgaaaccgg
     3541 atattacgaa aagtgatatt accattaatt tccggtaatg ccagtttccc atgataactt
     3601 tcagttggag agttaagcac atcaccaagg cgggtaactg atataccaac ctgctggaaa
     3661 tcctgccaga tttgtgcaag gcgaataacc ggtgcaacaa tctgaccagc aagcatatta
     3721 aaagcaatta actgaccaat acttaaatcc ccggaaataa ccaggtgtgc tcccaaccac
     3781 aggttgatga tcataacagt cttttgtatt aactgtattc cttgttgacc aatggtggct
     3841 aatactgtca ctttaaagcc tgcagcaaca tatcctgcca attgtttgtc ccatatgttc
     3901 gtcatctgag gtgagactgc catagctttt atagtgttaa tcgccgtgac tgattccacc
     3961 aggaaagatt gattatccgc attccgtgaa aacttatcat caaggcgacg tcgcaaaatg
     4021 gggctaataa aaacagacca tgcagcataa cagggcagcg aaaataagat caccagagta
     4081 agctttgggc tgtaatacca cattaccgca aaaaatatga atgaaaataa taagtccaga
     4141 acagatgtta atgcctgtcc tgtcagaaaa ttacggatct ggtctaattc tcttaccctg
     4201 gcaacagtat caccaacacg acgactctca aaataagaga tcggtagcgc cagtaaatgc
     4261 cggaagagtt tggcacccaa ctcaacatca atccgacttg tactatgtgc aaaaatgtaa
     4321 gttcttaaac cgctgagtat aatctcaaac accaccacaa cagataatgc gacagtaata
     4381 acattaaggg ttgaaaaccc cctgtgtact aatactttgt ccataaccac ctgaaaaaaa
     4441 aggggggtta ttaatgcaaa taattgtaaa aaaacagata caacaagggt t
//
LOCUS       DAFGPF010000218         4433 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFGPF010000218 DAFGPF010000000
VERSION     DAFGPF010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.220"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            178..1086
                     /locus_tag="LSX49_005035"
     CDS             178..1086
                     /locus_tag="LSX49_005035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBL7171297.1"
                     /translation="MKAPVSITSFRPQKSIAIAIGVLAVVVLPFLSYYTVNEGERGIL
                     LRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFH
                     IKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDLQNA
                     MRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVT
                     QAQAEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVAL
                     TTAERWDGKLPDTMIPGSTVPFISTK"
     gene            complement(1293..3284)
                     /gene="tkt"
                     /locus_tag="LSX49_005036"
     CDS             complement(1293..3284)
                     /gene="tkt"
                     /locus_tag="LSX49_005036"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708699.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL7171298.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIVGMTTFGESAPAEQLFEEFGFTVDNVVAKAKALL"
     gene            3562..4320
                     /gene="loiP"
                     /locus_tag="LSX49_005037"
                     /gene_synonym="yggG"
     CDS             3562..4320
                     /gene="loiP"
                     /locus_tag="LSX49_005037"
                     /gene_synonym="yggG"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HBL7171299.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSSGLLSSGAEAFQAYSLSDAQ
                     VKTLSDQACQDMDSKATIAPANSEYAKRLTTISRALGDNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVLGHEMGHVALGHVKKGMQVALGTNAIRVAAASA
                     GGIVGSLSQSQLGDLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGVK"
BASE COUNT         1066 a         1157 c         1168 g         1042 t
ORIGIN      
        1 tttgttattg tatttgtgat gcatatctct atttatttat tgaatgtccg aaagcatact
       61 tttctaatgc aatgtttttt cgctataccc ctttatagat tctgaattct cacctgccag
      121 ctgttttctc ctccccccat gtgacatatt cccatacttt actcaaggaa gattcatatg
      181 aaagcacctg tttcaataac ctcatttcgc ccacaaaaat ctattgctat cgccattggc
      241 gtgcttgccg tggttgtgct gccatttctc tcgtattaca ccgttaatga aggtgaacgc
      301 ggcattttgc tgcgctacgg aaaaatcgta aaagttgccg agccggggct gggttttaag
      361 atccctttta tggaaagtgt agagaaaatt tccacgcgta atcaggctgt ggtctatcag
      421 ggattacagg cctacagccg cgaccagcaa ccggcacaaa tgacggtatc agtcagcttc
      481 cacattaaac cttcagaagc aggcgcggtt tataccacct acaacaccat tgaagcatta
      541 aaagatcgtc tgattgtccg tcagttgcca actcaactgg agaacgtttt cggccaatat
      601 accgccatca gcgcggtaca ggatcgtaca aaactggttc aggatctgca aaatgcaatg
      661 cgtaaagccg ttgttggccc ggtggtgatt gatggtgtcc agattgaaaa tattgatttt
      721 tctgacgctt atgaaaagtc gattgaagac cgaatgaaag cagaagtcgc cattgccaca
      781 cgtaagcaaa atctggaaac agagaaaatc caagcgcaaa tagcagtaac tcaggcccag
      841 gcagaagcag acagtaaact ggcggcagcc aaagcagaag ctgagaccat tcgcgtaaga
      901 ggcgcggcag aggctgaaac tattcgttta aaaagtgcgg ctgaagcaga agctatccgc
      961 ctgcgcggtg aagctctgcg ggagaatccc ggacttgttg ccctcaccac tgctgagcgt
     1021 tgggacggta aactgcccga taccatgatc cccggcagca cagttccgtt tatctctact
     1081 aagtaaaaaa aggccgcttt cgcggccctt gagactgata gcaaagacaa aactgcctga
     1141 tgcgctacgc ttatcaggct gcaatatgtt gaatttgcaa aatcttgtag gacggataag
     1201 gcgttcacgc cgcatccggc ataaacaacg cgcactttgc caacaatctg aagggccgca
     1261 tttgcggccc ttctcacaaa gcatcttacc gattacagca gcgcttttgc tttcgcaaca
     1321 acgttgtcaa cggtgaagcc gaactcttca aacagctgct ctgccggagc agattcaccg
     1381 aaggtggtca tgccgacgat agcaccgttc aggccaacat acttgtacca gtagtcagca
     1441 atgccagctt ccaccgcaac acgagcggta accgctttcg gcagtacgga ttcacggtaa
     1501 gccgcgtcct gcttgtcgaa tgcgtcggta gacggcatgg aaaccacgcg cgctttcacg
     1561 ccttcggcag tcaatttttc gtatgccgct acagccagtt caacttcaga accggtcgcg
     1621 atgaagatca gttccggctg accagcacag tctttcagca cataaccacc gcgcgcgatg
     1681 tttgccagct gctcttcagt acgttcctgc tgcgccaggt tctgacggga gaggataagc
     1741 gcagtcgggc cgtcctgacg ttcaacgccg tatttccacg ctaccgcgga ttcaacctgg
     1801 tcacacggac gccatgtaga catgttcggg gtcacgcgca gagaagcgac ctgctctacc
     1861 ggctggtgag tcgggccatc ttcgcccaga ccgatggagt cgtgggtgta aaccatcacc
     1921 tgacgctgtt tcatcagcgc agccatacgt acggcgttac gtgcgtattc cacgaacatc
     1981 aggaaggtgg aggtgtacgg caggaaacca ccgtgcaggg agataccgtt ggcaatcgca
     2041 gtcataccga attcacgtac accgtagtgg atgtagttac ccgcagcatc ttcgttgatt
     2101 gctttagaac cagaccacag ggtcaggtta gacggcgcca ggtctgcaga accgccgagg
     2161 aattccggca acagcggccc gaacgcttcg atagcattct gagacgcttt acggctggcg
     2221 atcttcgccg ggttagcctg cagtttagca atgaactctt tcgctttcgc gtcgaagtca
     2281 gacggcattt cgcctttcat acggcgggta aattcagcgg cttcctgcgg ataagctttc
     2341 gcgtaagcag cgaatttctc gttccatgcg gactctttcg cctggcctgc ttctttcgca
     2401 tcccactgag catagatttc agacgggatt tcgaacggcg cgtatttcca gcccagctgt
     2461 tcgcgggtca gggcaatttc agcgtcgccc agcggcgcac cgtgggagtc gtgggtaccg
     2521 gctttgttcg gggaaccgaa accgatgatg gttttgcaca tcagcaggga cggtttgtca
     2581 gtcactgcgc gcgcttcttc tactgcgcgt ttgatggatg ccgcgtcatg accgtcgatg
     2641 tcgcgaataa cgtgccagcc gtaagcttcg aaacgcattg cggtgtcgtc ggtaaaccag
     2701 ccttcaacgt gaccatcgat agaaataccg ttgtcatcgt agaacgcaat cagtttaccc
     2761 agcttcagcg tacccgccag agagcaaact tcgtgggaga tgccttccat catgcagccg
     2821 tcgcccatga aggcgtaggt gtagtggtcg acgatgtcgt ggcccggacg gttaaactgc
     2881 gccgccagcg ttttttctgc aatcgccata ccgactgcgt tggcaatacc ctgacccagc
     2941 ggaccggtgg tggtttctac acctgcggtg taacccactt ccgggtggcc cggagtttta
     3001 gagtgcagct gacggaagtt tttcagttct tccatcggca gatcgtaacc ggtgaggtgc
     3061 agcaggctgt agatcagcat ggagccgtgg ccgttggaca gcacgaagcg gtcacggtca
     3121 gcccaggacg gattctgcgg gttgtgtttc aggaaatcac gccacaggac ttcggcaatg
     3181 tcagccatac ccataggggc acccgggtga ccggatttgg ctttctgtac tgcgtccatg
     3241 ctcagcgcac gaatagcatt ggcaagctct ttacgtgagg acattttgac tccagatcgg
     3301 atgatgaagg gcacgccctt aacgacttga cgacagcgcg ttttgggcta cgccggaaaa
     3361 tttgccaaca atttaccgca agccgcgcgt catgtacatg gaacatcctt ttgccgcttc
     3421 agaaatctct ggatcatgct cgcatgttgc gcaatctact cgccggtcca ctgcactttt
     3481 ccttatactt cgattgagcg tcaattcacc tgcagatggc gcatttttag aataatcctg
     3541 accttgtgcg gaagagaaaa catgaaaatt cgcgccttat tggtagcaat gagcgtggca
     3601 acggtactga ctggttgcca gaatatggac tccagtggac tgctctcatc aggagcggaa
     3661 gcttttcagg cttacagttt gagtgatgcg caggtgaaaa ccctgagcga tcaggcatgt
     3721 caggatatgg acagcaaggc gacgattgcg ccagccaata gcgaatacgc taaacgtctg
     3781 acgacaattt ctcgcgcgtt aggcgataac atcaatggtc agccggtgaa ttacaaagtg
     3841 tatatggcga aggatgtgaa cgcctttgca atggctaacg gctgtatccg cgtctatagc
     3901 gggctgatgg atatgatgac ggataacgaa gtcgaagcgg tgctcggtca cgaaatgggg
     3961 cacgtggcat taggccatgt gaagaaagga atgcaggtag cacttggtac aaacgcaatt
     4021 cgcgttgcgg cggcctctgc aggcggaatt gtcggcagtt tgtcacaatc acaactagga
     4081 gacctgggcg aaaagctagt caattcgcaa ttctcccagc gccaggaagc agaggccgat
     4141 gattactcct acgatttgct gcgccaacgc ggcatcagtc cggctggcct tgccaccagc
     4201 tttgaaaaac tggctaaact ggaagaaggt cgccaaagtt caatgtttga cgaccaccca
     4261 gcatccgccg aacgcgccca acatattcgc gatcgtatga gcgcggatgg agttaagtaa
     4321 ggcatggtgg tgccaaacgt aggtcagata aggcgtttac gccgcatctg acatgaatgg
     4381 cacatttgtt atcctgtgcg cgttgccgga tgcgatgctg gcgcatctta tcc
//
LOCUS       DAFGPF010000219         4341 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.221, whole genome shotgun sequence.
ACCESSION   DAFGPF010000219 DAFGPF010000000
VERSION     DAFGPF010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4341
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.221"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            7..963
                     /locus_tag="LSX49_005038"
     CDS             7..963
                     /locus_tag="LSX49_005038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020235731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2345 domain-containing protein"
                     /protein_id="HBL7171300.1"
                     /translation="MTIQNYKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQLNL
                     GHLVDAGKQQRGEGFELRTDLWGAVRAKKGIFISADAQDKAQGQVREMADIISELNSL
                     SDKIQKLSDDAATANADPADMAAQIALITSRINDLTASVILMHAPKGVAVASGEHLQL
                     AAVKNLQINAGNNADIGVVKNMFIGVGRALSVFVRKAGIRLIANKGAVSVQAQHDLME
                     LLAKKSIEIVSTEDEIKITAKKKITINGGGSYIRIEGSGIEPGTPGDYNVKAVHYGRQ
                     PKASEKVPMPEFPILSAVDSSDFCLECLLNAIKNDDAVVEGV"
     gene            966..1787
                     /locus_tag="LSX49_005039"
     CDS             966..1787
                     /locus_tag="LSX49_005039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4123 domain-containing protein"
                     /protein_id="HBL7171301.1"
                     /translation="MSSEQQLADHWLKRNETLNAFILFEGGALSQEMLQIMMEHYKYR
                     RISLYQLPDLKKVAAYGPWLVRIESEKDLAMVLVGKLPVAGITFSELQLEPLASRLAV
                     GCMAKTPDGREVLLRYYTPRVLKQLAARPDMDWHPVMFSQIESWWMLEDTRWQRLNMP
                     LTVANNSDETVEIITLDEPLWQKIADRGDVSALLREWRTMKTSEHFPPCIQRNMVEKA
                     LNKAQVVGLTKPLDQKIYALSYLNGKKAYLESAEFQVMLEKVKRNEISLSDLGRQ"
     gene            1831..2358
                     /locus_tag="LSX49_005040"
     CDS             1831..2358
                     /locus_tag="LSX49_005040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3304 domain-containing protein"
                     /protein_id="HBL7171302.1"
                     /translation="MGLFTRLEKFDQKLTRGYARWGRWVWRMLIAIPVAYFLLCVGIS
                     IWGAPTGGVILVIHSELDRPILGFSVNGMAGANAFAHGGGSTTCCGDIRGKEAEVVWT
                     LSTTRAQYNTGLREEVRRITLPLPERKHGQDFLHVHFLPGDKVFLGWSEGAGSPYEKR
                     KEPSYPSRKNQEAQP"
     gene            2355..4223
                     /locus_tag="LSX49_005041"
     CDS             2355..4223
                     /locus_tag="LSX49_005041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2235 domain-containing protein"
                     /protein_id="HBL7171303.1"
                     /translation="MISESVISAAVRAQQSEDGKVGNCGRIWHVAFFFDGVGRNIDRD
                     ATDCRLSNIARLFRAYPDEQKNTGDTCYNKFYFSGMGTAYHDDSVDNIHALMDIGLDN
                     FLEDMKSLPEDTISDAGESVIKGEKKWTDVLGNLLEDLNNPVEWVKGIGKMAAKSVGK
                     AGIESTPWLRDSEAMSAYFMTGEPVRLEAAKRLFKKFYTENMKGDVPIKKISVSLYGF
                     DLGATLARKFLDNFLKEVCLKNKEKKHQYKNALVDIAFIGLFDCSRHSPTSSNNGLDY
                     FFMWLGLPGKMIGSVLGEKAIDQDSPLPDVVNNALHLVAAHERRPWRGLYLLGKKTDT
                     ANKKYREELLPGCSEDIGGGLKPDEQKPSAELCRVALYNMYHAACQAGVPFPDFDTLD
                     QYDTKVASYFIMNDAVQGGSVNYWVSRYQREEVKDKVFSEAMQEKYLDNYFLWLGEQY
                     YMYQYERERLDKELTSAHRGKISDYGPLAGTGINPNTNADDIKSQISELDSLWGWLND
                     VKSVAIGLRNDFIVNPRKNDSRIKLKPQVYNAAVNRAVKFLEFSRAVYNDKNLPSSSS
                     LTANTLYSFFVHDIQKVDHTPSISEDFFLRRSSEIPDADEPPGNKDDGKKHTRRDD"
BASE COUNT         1250 a          826 c         1154 g         1111 t
ORIGIN      
        1 gaccatgtga ccattcagaa ctacaagcgc aacgtgctac gcaccccggc gaacaacaaa
       61 atccgcctcg acgatgagcg cggcaaagag catatcaagg tcagtaccga gtacggcggc
      121 aagagccagc tcaacctcgg tcatctggtg gatgccggga aacagcagcg cggggaaggt
      181 tttgaactgc gtaccgatct gtggggtgca gtacgggcaa agaaaggcat ctttatcagc
      241 gccgacgcgc aggacaaggc gcagggtcag gtgcgcgaaa tggccgacat tatcagcgaa
      301 ctgaacagcc tgagcgataa aatccagaaa ctgtctgacg atgcggccac ggcgaacgcc
      361 gatccggcgg atatggccgc gcagatagca ttgataacca gccggataaa tgacctgacc
      421 gcctcggtga ttttgatgca cgcaccgaaa ggcgtggcgg tcgccagcgg cgagcacctg
      481 caactggccg cggtgaaaaa cctccagata aatgcgggaa acaacgccga tatcggcgta
      541 gtgaagaata tgtttatcgg cgtgggacgg gcgctgagcg tgtttgtacg caaggcgggt
      601 atcaggctga ttgccaataa aggcgcagta tcggtacagg cgcagcacga tctgatggag
      661 ttactggcga aaaaatcgat agagatcgtc agtaccgaag atgagattaa aatcaccgcg
      721 aagaaaaaaa taacgattaa tggtggtggg agttatatcc ggatagaggg tagcggcatt
      781 gagccgggaa cgccggggga ttataacgtc aaagcggtac attacgggcg tcagcctaaa
      841 gcctcggaga aggttcctat gccagaattt cccatccttt cagccgtgga ctcatccgat
      901 ttttgtcttg aatgcctgct gaatgccatc aaaaacgatg acgctgttgt tgaaggagtg
      961 taatcatgtc ttcagaacaa caactggcag accactggct taagcgaaac gaaacgttaa
     1021 acgcctttat tttatttgaa ggtggagcgc tctctcagga aatgcttcag atcatgatgg
     1081 agcattataa ataccgacga atttccctgt atcaactgcc cgatcttaaa aaggtagcag
     1141 cttacggtcc ctggttggtt cgtattgaaa gtgaaaagga tctggcgatg gtgcttgtcg
     1201 ggaaactacc tgtcgcaggc attactttct ccgaattgca gctggagcca ctggcgtctc
     1261 ggcttgctgt gggatgtatg gcaaaaacgc cggatggtcg tgaagttctg ctgaggtact
     1321 acacgccccg agtgctgaaa caactggctg cccggcctga tatggactgg catccggtaa
     1381 tgttttctca gatagaatca tggtggatgc tggaagatac gcggtggcaa aggctgaaca
     1441 tgccgcttac tgtggcaaat aacagcgatg agacagtgga aatcataacg cttgatgaac
     1501 cgctctggca gaaaatagcg gatcggggag atgtatctgc gcttttaaga gagtggcgca
     1561 ccatgaaaac gagtgagcac ttcccgccct gtattcagcg aaatatggtg gagaaggcct
     1621 tgaataaggc tcaggtggtc ggattgacaa agccactgga tcagaaaatt tatgcgttga
     1681 gctatctgaa tggaaagaaa gcgtatcttg agtcagccga atttcaggtc atgctggaaa
     1741 aggtgaaacg aaatgaaata tcgctgtctg accttggtcg ccagtgacat acatctttgc
     1801 caaccaattg ataaaaggga ataaaatctg atggggctat ttacccgact ggaaaaattt
     1861 gaccaaaagc ttacgcgtgg ttatgcccgc tgggggcgtt gggtgtggcg gatgctaata
     1921 gcgatccccg tggcttattt tttactgtgt gtaggaatat caatctgggg agctccaact
     1981 ggaggagtca tattggtgat ccatagtgaa ctggataggc caatattagg attcagcgtg
     2041 aacggcatgg ctggggcaaa tgcgtttgca catggtggag gttcaacgac ttgctgcggt
     2101 gacatcagag ggaaagaagc tgaggtcgtc tggacattga gtacgactcg cgctcagtat
     2161 aatacgggac tgcgtgaaga agttcgacgt atcactctgc ctttgcctga aaggaaacat
     2221 gggcaggatt ttttgcatgt acatttcttg cctggtgata aggttttttt gggttggagt
     2281 gaaggagctg gttcgcccta tgagaaacga aaagaacctt cttatccgag tcgaaaaaat
     2341 caggaggcgc agccgtgata agtgaatcag tgatttccgc agctgtacga gcacaacagt
     2401 cagaagatgg taaagtggga aattgtggcc ggatctggca tgtcgctttc ttttttgatg
     2461 gagtgggacg aaatatcgac cgggatgcga cagactgccg tttgagtaat attgcccgcc
     2521 tgttccgggc atatcctgat gaacaaaaaa atacaggtga tacttgttat aataaatttt
     2581 atttctccgg aatgggcact gcctaccatg acgattctgt cgacaatatt cacgctctta
     2641 tggatattgg tttagataac tttctggagg atatgaaaag tctgccagag gatactatat
     2701 cggatgcagg ggagtctgtt attaaaggag aaaagaaatg gacggatgtg cttggtaatc
     2761 tccttgagga tctcaataat ccggtagagt gggttaaagg gattggcaag atggcggcta
     2821 agtcggtagg caaagcagga attgagtcca caccttggtt gcgtgatagc gaagccatga
     2881 gcgcctattt tatgacggga gaacccgtac gccttgaagc tgcaaagcga ttgtttaaga
     2941 agttttatac ggaaaatatg aagggagatg ttcccatcaa aaaaatttct gtttcattat
     3001 acggttttga ccttggagct acactggcac gtaaattttt ggataatttt cttaaggaag
     3061 tttgcctgaa aaataaagaa aaaaaacacc aatataaaaa cgcgttggta gatattgctt
     3121 ttattggtct ttttgactgt tctcggcatt caccgactag tagtaataat gggttggact
     3181 atttttttat gtggttgggt ttaccaggga aaatgattgg ttcagtatta ggtgaaaaag
     3241 ctattgatca ggactcacca ctgccggacg tagtaaataa cgcacttcac cttgtagcag
     3301 ctcatgaacg gcgtccatgg cgtggtctgt atctgttggg gaaaaaaacg gatacagcga
     3361 ataaaaaata cagggaagaa ctgcttcccg gttgtagtga agatattggt ggtggcttga
     3421 aaccggatga acagaaaccc agtgcagaac tgtgcagggt tgcactatac aatatgtatc
     3481 atgcagcatg tcaagctggt gtgccatttc ctgattttga cactttggat caatatgata
     3541 cgaaagttgc cagctatttt attatgaatg atgctgttca gggaggatct gtaaattact
     3601 gggttagtcg ttatcaaaga gaggaagtga aggataaagt atttagtgag gcaatgcagg
     3661 agaagtatct agataactat tttctctggt tgggtgagca atattatatg tatcagtatg
     3721 aacgggaacg tctggataag gagttgacat cggctcatcg tgggaaaata agtgactatg
     3781 ggccacttgc aggtacggga attaatccaa atactaacgc tgatgatata aaatcgcaga
     3841 tttcagaact tgactcacta tggggatggt tgaatgatgt aaaaagtgta gctattggat
     3901 tacgaaatga ctttatagtc aacccgagga aaaatgatag ccgaataaaa cttaaacctc
     3961 aggtttataa tgctgctgtc aatcgggctg tgaaattcct tgagttttct cgcgcagttt
     4021 ataatgataa aaatctgcca tcatcatcat ctttgacggc aaatacacta tattcctttt
     4081 ttgtgcatga tatacaaaag gttgatcaca caccttctat atctgaagat ttcttcttac
     4141 gtcgctcatc tgaaattcca gatgcggatg aacctccagg aaataaagat gatggaaaga
     4201 aacatactcg cagggatgat tagaaattat aagtagctta ctttaattag ttatattttt
     4261 tgcatttttc cctttttaaa gagaatcata cttggattta tttttcataa atataaagga
     4321 gtacagagat ggatatcccg a
//
LOCUS       DAFGPF010000220         4278 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.222, whole genome shotgun sequence.
ACCESSION   DAFGPF010000220 DAFGPF010000000
VERSION     DAFGPF010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4278
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.222"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..299)
                     /gene="tuf"
                     /locus_tag="LSX49_005042"
     CDS             complement(<1..299)
                     /gene="tuf"
                     /locus_tag="LSX49_005042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL7171304.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQM"
     gene            complement(414..489)
                     /locus_tag="LSX49_005043"
     tRNA            complement(414..489)
                     /locus_tag="LSX49_005043"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(454..456),aa:Thr,seq:ggt)
     gene            complement(496..570)
                     /locus_tag="LSX49_005044"
     tRNA            complement(496..570)
                     /locus_tag="LSX49_005044"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(535..537),aa:Gly,seq:tcc)
     gene            complement(687..771)
                     /locus_tag="LSX49_005045"
     tRNA            complement(687..771)
                     /locus_tag="LSX49_005045"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(735..737),aa:Tyr,seq:gta)
     gene            complement(780..855)
                     /locus_tag="LSX49_005046"
     tRNA            complement(780..855)
                     /locus_tag="LSX49_005046"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(820..822),aa:Thr,seq:tgt)
     gene            1217..2167
                     /gene="coaA"
                     /locus_tag="LSX49_005047"
                     /gene_synonym="panK"
     CDS             1217..2167
                     /gene="coaA"
                     /locus_tag="LSX49_005047"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL7171305.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2196..3161)
                     /gene="birA"
                     /locus_tag="LSX49_005048"
     CDS             complement(2196..3161)
                     /gene="birA"
                     /locus_tag="LSX49_005048"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HBL7171306.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGESLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAEQILGQLDGGSVTVLPVIDSTNQYLLDRIGELK
                     SGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNSLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(3158..4186)
                     /gene="murB"
                     /locus_tag="LSX49_005049"
     CDS             complement(3158..4186)
                     /gene="murB"
                     /locus_tag="LSX49_005049"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBL7171307.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAEGQPVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRD
                     SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKVLLAQFPTAPNYPQADGSVKLAAGWLIDQCQLKG
                     MQMGRAAVHRQQALVLINEDNAKSEDVVQLALHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
BASE COUNT         1109 a         1053 c          960 g         1156 t
ORIGIN      
        1 tccatctgag cagcaccggt gatcatgttt ttaacatagt cggcgtgccc cgggcagtct
       61 acgtgtgcgt agtgacgggt cggggtgtcg tattcaacgt gagaagtgtt gatggtgata
      121 ccacgagcct tttcttccgg cgcgttatcg atctggtcga atgcgcgagc agcaccgccg
      181 taggttttag ccagtacggt agtgattgca gcggtcagcg ttgttttacc atggtcaacg
      241 tggccgatag taccgacgtt aacgtgcggt tttgtacgtt caaacttttc tttagacatc
      301 gattgtccct ctaagacacg gataaatcgg tgatatcacc acatcaacca ggcaacatgc
      361 ccgacttgtt gaatgcaata aacagaagga aaaaacaggg aggagaaaag aagtggtgct
      421 gataggcaga ttcgaactgc cgacctcacc cttaccaagg gtgcgctcta ccaactgagc
      481 tatatcagca catcttggag cgggcagcgg gaatcgaacc cgcatcatca gcttggaagg
      541 ctgaggtaat agccattata cgatgcccgc atcctggaac tcggctacct gattttcatt
      601 ctgcactgaa tatcgagaga agctctcttt attcgagccg gtaagcgaac ttatcgtctc
      661 gggctacgcc atcgcgtggc cgaaattggt ggtgggggaa ggattcgaac cttcgaagtc
      721 tgtgacggca gatttacagt ctgctccctt tggccgctcg ggaaccccac cggacttgat
      781 ggtgccgact accggaatcg aactggtgac ctactgatta caagtcagtt gctctaccta
      841 ctgagctaag tcggcatcaa gtagcgcgca ttctatggag acatgcgagt tcatgcaact
      901 aaaaaattgc ataatttgtt ttattggtca cattttatgc gacacgatga agaaacagcc
      961 gaacggaggg cagattagca cactttttca acatcattgt gctcaacaat gtgctcctgc
     1021 taaaccataa ttctttttat cagatggaat atctgtcaca ttgcttttca acgatagctt
     1081 cctgggagag attttttctt attattcctc cccatctggt gttaccctcc tgcccattaa
     1141 cccattcaac agaactgtga cgcgccatgg caaatatcgc tttgccgata gagctatgac
     1201 cgccagaaac atgcttatga gtataaaaga gcaaacgtta atgacgcctt acctacagtt
     1261 tgaccgcaac cagtgggcag ctctgcgtga ttccgtacct atgacgttat cggaagatga
     1321 gatcgcccgt ctcaaaggta ttaatgaaga tctctcgtta gaagaagttg ccgagatcta
     1381 tttacctctg tcacgtttgc tgaacttcta tataagctcg aatctgcgcc gtcaggcagt
     1441 tttggaacag tttcttggta ccaacgggca acgcattcct tacattatca gtattgctgg
     1501 tagtgtcgcg gtggggaaaa gtacaaccgc ccgtgtattg caggcgctat taagccgttg
     1561 gccggaacat cgtcgtgttg aactgatcac tacagatggc ttccttcacc ctaatcaggt
     1621 tctgaaagaa cgtggtctga tgaagaagaa aggcttcccg gaatcgtatg atatgcatcg
     1681 cctggtgaag tttgtttccg atctcaaatc cggcgtgcca aacgttacag cccctgttta
     1741 ctcgcatctt atttatgatg tgatcccgga tggagataaa acggttgttc agcctgatat
     1801 tttaattctt gaagggttaa atgtcttaca gagcgggatg gattatccac acgatccaca
     1861 tcatgtattt gtttctgatt ttgtcgattt ttcgatatat gttgatgcac cggaagactt
     1921 acttcagacg tggtatatca accgttttct gaaattccgc gaaggggctt ttacagaccc
     1981 ggattcctat tttcataact acgcgaaatt aactaaagaa gaagctatta agactgccat
     2041 gacattgtgg aaagagatca actggctgaa cttaaagcaa aatattctac ctactcgcga
     2101 gcgtgccagt ttgatcctga cgaaaagtgc taatcatgca gtagaagagg tcagactacg
     2161 caaataattt tcaggggagc taatgctccc ctttcttatt tttctgcact acgcagggat
     2221 atttcaccgc ccatccaggg ttttattatt ccatcctgct caagtaataa agcaccctgt
     2281 ttgtctattc cgcgtgaaat gccaaatatt tctttatcac caatgataag tttcactggg
     2341 cgattaataa aattatccaa cttttcccag cgcgaaagat aaggtgccaa tccttcttgc
     2401 tcgaagagtt ccagcgccgc gcgtaattca cgtatcagca tggccgcaag actattacga
     2461 tcgagattga tcccggcttc ctgcagcgtg atccaccctt gattaacgac actctcttca
     2521 acacgacgca ttgccatgtt gatccctgcg ccaatgacta tttgcgccgc atcgccggtt
     2581 ttgccagtca gctccacaag aatgcctgcc agcttgcgat cctgcagata gaggtcatta
     2641 ggccatttaa cacgaacttt atctgcaccc agcttgcgta atacttccgc catcacgata
     2701 ccgataacca gacttaaacc aatcgccgcc gccgggcctt gttccagacg ccagaacatc
     2761 gacaaatata agtttgcgcc aaaaggcgaa aaccatttcc gaccccggcg accacggcca
     2821 gcctgctggt attctgcaac acaggcatcg cccgatttaa gctctccgat acgatcaaga
     2881 aggtactgat tcgtggagtc aataacgggc agcacagtta cactaccgcc atccagctga
     2941 cccaatatct gttcagcatt aagtaactgg ataggctcag gcaggctgta tcctttaccc
     3001 ggaacggtaa agacatcaac gccccagtca cgcagtgtct gaatgtgttt attaatagcc
     3061 gcccggctca ttcctaacga ttcacccaac tgctcaccag agtgaaattc gccattcgct
     3121 aacagcgcga ttaatttcag cggaacggta ttatccttca tgaaatcgtc tccactgcgc
     3181 taacttcacc tgatgcacca ataaagcgaa cttcaggctc aagccagaca ttaaattttt
     3241 cacccacttt ttgtcttaca tgaagtgcca gttgcaccac atcttcgctt tttgcattgt
     3301 cttcattaat gaggactaac gcctgttgac ggtgcaccgc agccctaccc atttgcatcc
     3361 cttttagctg gcactgatcg ataagccaac ctgctgccag ttttactgaa ccatccgcct
     3421 ggggataatt tggtgctgtt ggaaattgtg ccagtaatac tttagccgtt tcggcagata
     3481 caacagggtt tttgaagaaa ctaccggcat tgccattcac ttttggatca gggagtttgg
     3541 tggtgcgcat atgacacacc gcattaaata cttgctgtgg cgttactgtt gtaggatcca
     3601 gacgagttaa gtcaccatac gtcagtacag gttgccactc ttttggcaga cgcaggccta
     3661 cggctacaat agcgaagcga tcctggtatt catgtttaaa aatactgtcg cgatagccaa
     3721 aacggcactc tttggcagtt aagcgcactt gcttgcctgt cgccagttca acacaatcaa
     3781 cataagcgca aactcgctgt aattctacgc cataagcacc aatattctgg ataggtgatg
     3841 agccgacaca accaggaatt aatgccagat tttccagacc aggcatacct tcctgcaaag
     3901 tgtattttac aaggcgatgc cagttttctc cggctcctac atgtaaatac cacgcatcag
     3961 gttcatcatg aatttcgata cctttgatcc ggttgatgat caccgtgccg cgatagtctt
     4021 ccagaaaaag tacattactt ccttcaccca gaataagaac gggttgtcct tctgcggttg
     4081 catgctgcca ggcattgagt aattgttgtt cgtcttcggc acatacaatg tgctgagcat
     4141 tatgatcaat gccaaatgtg ttccagggtt ttaaggagtg gttcatagct gctttcctga
     4201 tgcaaaaacg aggctagttt accgtatctg tggggggatg gcttgtagat atgacgacag
     4261 gaagagttta tagaaacg
//
LOCUS       DAFGPF010000221         3866 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFGPF010000221 DAFGPF010000000
VERSION     DAFGPF010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.223"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            83..>3866
                     /locus_tag="LSX49_005050"
     CDS             83..>3866
                     /locus_tag="LSX49_005050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7171308.1"
                     /translation="MCSKRNIGDMKITVLNQRYKKHFGYPHILMGDVKVTVSAMIACA
                     VLLHPNKLFASVAGTSLPYQTYRDFAENKGEFRPGAENVPLYDKNGNPVTTLNKAPMI
                     DFSSNDSTGVATLVSPQYVVSVKHNVGYQYVKFGYADDSSYALVDRNNHWRDFHTPRL
                     NKIVTEVTPLDITNAGTAKGTYQNADRFPVFYRVGTGTQYVKDTNGKITYLMGAYSYK
                     TGGIVNTPAISDWSFVTNTTNTPLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSYAG
                     VNGNTNWYTIIPAGDVKNTMKQDADAPVNTKQGEGDIHWSYDEKTGLGSLTQGSTSWE
                     MHGNLGATWPASLNSGKDLTFQGGGTVVLENTVNQGAGTLTFDDDYIVKPVDTQTWKG
                     GGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADD
                     NGLSQAFSSVSIVSGRPTLVLNDDKQINPDNIKWGYHGGKLDINGNSLTFHKLNGADD
                     GAILTNSGSMANVNLDFNSPDTTATIANIWHGHFTGNLNINNEVTAGTQNDFAIDGGV
                     NAQGSITQQNGRLFMQGHPVVHAVSSQDVANKLKALGDNSVLTQPVSFTQNDWENRQF
                     SMAELNLQNAEFNLARNASLNTRINAEHSTVTLGSEDLYIDLNDGNGVATKPTLGKSK
                     ATAEDDQSRFNGHVQLQQGSALTINEHFAGGIDSADSATTITSTDTTLNQLSRFTQSS
                     LSLGEGAKLTATAGLLSDGTVSSNAGASLSLLSDQPGTMYSAQSWELSGQDTSLNVGA
                     GGIITGDINANDAASISFGTTDINQSTNYYGNINAPLASVTMKDTAWQVNKQSVAKSL
                     TLNGSTLSFNRFGQGGLTSDTLEATNSSFIINADGKAADTVTVNQALTGGNNTLVVIP
                     TTNSVKQGGDPVSLVTAPKNTQSNIFTLNPVSINAGFHSFTPQLDVLETDVNKQWRLE
                     GFYIQPDKAALRTGKSFMDLGYKNFITEINNLNDRMGDLRHTHGETGAWARLNSGSGS
                     ATDGFTGSYTHLQIGADRKHIIEGGELFTGVTATFTSSNNRGTGWSGRTKSTGIGVYA
                     SAMFDSGLYVDTIGKYVRHDNHYSSSALGMPEQDYGSHSWYLGAEAGWRFSLPDETYI
                     QPQTELIYGTVSENQFAWQFNGGEIYMQRKQMQPLIGRTGIEFGKTFRGKDWEMTALT
                     GINYQYDLFKPTVTAFKDLAGDTYINNGKDSRVVFNVGVNTKIKENTRISLNVERSE"
BASE COUNT         1161 a          759 c          936 g         1010 t
ORIGIN      
        1 tgcttggatt tattagtttt aagatctttc gagtcagaag atatatgaat agatagaata
       61 gaaattcaat tgtcggaatg aaatgtgttc aaaaagaaat ataggtgata tgaaaattac
      121 agtccttaat cagcgatata aaaaacattt tggttatcct catattctga tgggtgatgt
      181 aaaagtaact gtttcagcaa tgattgcttg cgctgtttta ttgcacccaa ataaattgtt
      241 tgcctccgtc gctggaacct cacttcccta tcaaacgtat cgtgattttg ctgagaataa
      301 gggagagttc cgtcctggcg cagaaaatgt tcctctatat gataaaaatg gcaatcccgt
      361 cacgacgctg aataaggcac ccatgattga cttcagctct aatgactcga ctggggttgc
      421 aacactggtt tcgccacagt atgtcgtcag cgttaaacac aatgttggtt atcaatatgt
      481 gaaatttggc tatgcagatg attcatccta tgcccttgtt gacagaaata accactggag
      541 agatttccac actccccgtc tcaacaaaat tgtcaccgag gttacacctc tggatataac
      601 caatgcgggt acagctaagg gaacctatca aaatgctgac cgtttccctg tgttctatcg
      661 agtaggtacg ggaactcaat atgtaaaaga tactaacgga aaaatcacct atttaatggg
      721 agcctactcg tataaaacag gtggaatagt aaatacgccg gctatatctg actggagttt
      781 tgtcacgaat accactaata ctccactctc aacctacggc actcccggtg acagtggctc
      841 tcctcttttt gcctgggatg cagaccaaaa taaatgggtt ttgttagccg ttctcaattc
      901 atatgcaggg gtcaatggca atactaactg gtacacaata attcctgctg gtgatgtaaa
      961 aaatacgatg aaacaagatg ccgatgcacc agtaaataca aaacaaggtg aaggggatat
     1021 tcattggtca tatgacgaaa aaacgggact tggttcatta acccagggaa gcacatcatg
     1081 ggaaatgcat ggaaatttgg gggcaacatg gcctgcttcg cttaatagtg gtaaagatct
     1141 aacttttcag ggcggcggta ctgtagtgtt agaaaatacc gttaatcagg gggctggcac
     1201 acttactttt gatgatgatt atattgtcaa gcccgttgat actcagacat ggaaaggcgg
     1261 cggaattatt gttaatggtg aacatcttgt tgactggcag attaatgggg ttactggtga
     1321 tagtttgcat aaactgggta cgggtacgtt aaaaattaac ggtaccggtg taaacccagg
     1381 aagcttaagt gtgggagacg gaaccgttat attggcacag cgtgctgatg ataacggact
     1441 gagccaggcg ttcagttctg tcagtattgt aagtgggcgt cctactctgg tgctaaacga
     1501 cgacaaacaa attaatccgg ataatatcaa atggggctat catggcggca agctcgacat
     1561 taatggaaac agtttgactt ttcataaact taacggggct gatgatggag ctatactgac
     1621 taacagtggc tccatggcta atgttaatct ggatttcaac agcccagata caacagccac
     1681 gattgctaat atctggcacg gccatttcac cggtaatcta aatatcaata atgaggttac
     1741 cgcaggaaca cagaatgatt tcgctattga tggtggagtg aatgctcagg ggagtataac
     1801 ccagcaaaat ggtcggctat ttatgcaagg acatccggtt gttcacgccg tcagcagtca
     1861 ggacgtagca aataagctaa aggcgctggg tgacaattca gtactgaccc aaccagtgtc
     1921 atttactcag aacgattggg aaaatcgaca gttcagtatg gcggagctta acttacaaaa
     1981 tgctgaattt aaccttgcaa gaaacgccag ccttaatacc agaattaatg ccgagcattc
     2041 taccgtgacg ttaggtagtg aggatcttta cattgatctc aatgacggga atggcgtggc
     2101 aaccaaacca acattgggta agtcaaaggc aaccgctgaa gatgatcaga gtcgtttcaa
     2161 tggacatgta cagttgcaac aaggatcggc actaactatt aatgaacatt ttgccggcgg
     2221 tattgatagt gcagatagtg cgacgacgat aacctctaca gataccacgc ttaatcagct
     2281 cagccgtttc acccaatctt ctttgtcatt aggtgaaggg gcaaaattga ccgctacagc
     2341 cggattactt tctgacggga cggtaagcag taatgccggg gcgagccttt ccttgctatc
     2401 agaccagcct ggaacgatgt attccgccca aagctgggag cttagcgggc aagacacgag
     2461 cttaaatgtt ggcgcgggtg ggatcatcac tggagatatc aatgccaatg atgcggccag
     2521 cattagcttt ggcacgactg atattaacca atccacaaat tactatggaa atatcaacgc
     2581 gccgttggca agtgtaacaa tgaaggacac tgcctggcag gtaaacaagc agtcggtggc
     2641 taagtcgctc actttgaatg gttcaacact gagctttaat cgtttcgggc aagggggact
     2701 gacgtcagat acgctggagg ccactaacag ttcgttcatt atcaatgccg atggtaaagc
     2761 agcagatacg gtgacggtaa accaggcatt gacagggggg aataacacac tggttgttat
     2821 tcctacgaca aattcagtaa aacagggcgg tgaccctgtg tcattggtta ctgccccgaa
     2881 aaatacacaa agcaatatat ttacacttaa cccggtttca ataaatgcag ggttccatag
     2941 ttttacaccg caacttgatg tgttggagac cgacgttaat aagcaatggc gtctggaggg
     3001 attttacata cagcctgata aagccgcttt gcggacaggc aagagtttta tggatctcgg
     3061 ttataaaaac tttattacag aaattaataa tctgaatgat cgtatggggg acttacgcca
     3121 tacccatggt gaaactgggg catgggctag acttaacagt ggttcgggct cagctactga
     3181 tggatttacc ggaagttata cgcacttgca aattggggca gacaggaaac atataattga
     3241 aggcggagag ttatttactg gagtaacggc gacatttaca agcagtaata accggggaac
     3301 tggttggtcg ggaagaacca aatcaacggg tattggtgtg tacgcttcag ctatgtttga
     3361 ctctggactc tatgtagata ctatcgggaa atatgtgcgt catgacaatc attactcatc
     3421 aagtgcgtta ggaatgccag aacaagatta tggctcgcac tcctggtatt tgggcgctga
     3481 ggccggttgg cgtttttcct tacctgacga aacatatata cagccgcaaa cagagttgat
     3541 ctacggtact gtatctgaga atcagtttgc ctggcaattc aatgggggtg agatctatat
     3601 gcaacgtaag cagatgcaac cattgattgg tcgcacagga attgaatttg gcaaaacatt
     3661 ccgcggcaaa gactgggaaa tgacagcgct gactgggatt aattatcagt acgatttatt
     3721 taagcctact gtgacagcgt tcaaggatct ggcaggtgat acatatatta ataatggtaa
     3781 agatagcaga gtggtattca atgtcggggt aaatactaaa attaaagaaa acactaggat
     3841 aagtctgaat gtggagcgtt ctgagt
//
LOCUS       DAFGPF010000222         3860 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFGPF010000222 DAFGPF010000000
VERSION     DAFGPF010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3860
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.224"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..273)
                     /locus_tag="LSX49_005051"
     CDS             complement(<1..273)
                     /locus_tag="LSX49_005051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171309.1"
                     /translation="MKVRSIGFTINNNNKNINTVDVMNAFINASNREHSRTDYTRKIL
                     ISDVNDFYYGLVVTFRNQKKNCKSQFVDGKFQLKIEDLQGSDKLANF"
     gene            538..741
                     /locus_tag="LSX49_005052"
     CDS             538..741
                     /locus_tag="LSX49_005052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171310.1"
                     /translation="MLKQQDMTETAAAVLHFLPADKWVTPRMMTRTIGVSEARCQLIL
                     TQLVLAGLAKDNGGYGNKFRRCQ"
     gene            892..1944
                     /locus_tag="LSX49_005053"
     CDS             892..1944
                     /locus_tag="LSX49_005053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBL7171311.1"
                     /translation="MKNTVKINSVDLINADCLHFIQSLPDDSIDLIVTDPPYFKVKPN
                     GWDNQWKGDEDYLKWLDHCLAQFWRVLKPAGSLYLFCGHRLASDIEIMMRERFNVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERVLFAEHYQGPYRGKSDGYAAKERELKQHIMA
                     PLISYFSDARAELGITAKQIAEATGKKNMVSHWFGASQWQLPNEADYRKLQALFSRIA
                     AEKFQEQQLEQPHHQLVASYDSLNRKYSELLDEFKSLRRYFSVSVSVPYTDVWMHKPV
                     QFYPGKHPCEKPADMLRQIINASSRPGDLVADFFMGSGSTIKAAMALGRRALGVELES
                     ERFNQTVKEINELVGK"
     gene            2012..2227
                     /gene="essD"
                     /locus_tag="LSX49_005054"
     CDS             2012..2227
                     /gene="essD"
                     /locus_tag="LSX49_005054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HBL7171312.1"
                     /translation="MKSMDKLTTGVAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDKRKAARGE"
     gene            2227..2724
                     /gene="rrrD"
                     /locus_tag="LSX49_005055"
     CDS             2227..2724
                     /gene="rrrD"
                     /locus_tag="LSX49_005055"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HBL7171313.1"
                     /translation="MPPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKD
                     IVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGAL
                     YSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWIYAGGKQWKGLMTRREIEREVC
                     LWGQQ"
     gene            2721..3188
                     /locus_tag="LSX49_005056"
     CDS             2721..3188
                     /locus_tag="LSX49_005056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HBL7171314.1"
                     /translation="MSRVTAIISALVICIIVCLSWAVNHYRDNAIAYKEQRDKKVSEL
                     KQATATITDMQQRQRAADVLDAKYTKELANAKAENDALRRKLDNGGRVLVKGKCSVPS
                     AAETSSASGMGNDATVELSPVAGRNVLGIRDGIIRDQTALRTLQEYIRTQCLR"
     gene            3176..3328
                     /locus_tag="LSX49_005057"
     CDS             3176..3328
                     /locus_tag="LSX49_005057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171315.1"
                     /translation="MPSMIAIILLIILHIWLCRQGGDHFWSESRLNISLLMLEVEHLA
                     RGKGLR"
BASE COUNT         1017 a          870 c          980 g          993 t
ORIGIN      
        1 gaaattagca agtttgtcac ttccttgaag atcttcaatt ttaagctgga atttaccatc
       61 aacaaattgc gacttacagt tctttttttg gtttctgaat gtgacaacta atccataata
      121 gaaatcattc acatccgaaa tgagaatttt acgagtatag tctgtgcgac tgtgttctct
      181 gtttgatgcg ttgataaaag cattcattac gtcaacggta ttaatatttt tgttattgtt
      241 atttattgta aatcctatgc ttctaacttt catgtgtatt ccaggaccga ctaaagatag
      301 cgagaatggg gacgcatagt ttataaaaac cctaacgcgt acgcaaaaag tattatatcg
      361 tgttaagagt ggttacttcg ccacacaact taaacccgcc gctgagcggt ttttttgtac
      421 ctgtaaacct ggtgcagtac agtaaacacg ctggtggtcg tgaatactgg ctttttatct
      481 tgctggcttt ttagacaaga gttattggta tgtcatgtta accagaagga aaaaaacatg
      541 ctaaaacagc aagatatgac agaaaccgcc gccgcagtcc ttcatttctt acctgctgac
      601 aagtgggtaa cgccacgcat gatgacgaga actatcggag taagcgaagc ccggtgccag
      661 ttaatactga ctcagttagt tctggcgggt ctggcgaagg ataacggcgg gtacgggaat
      721 aaattcagac gctgccagta atggcggttt cctgctgtga aaatgggcgg ctggtgggtg
      781 ttggtagcac ctgccagcca ttcgctcatg cttactggtc acaagcgaac cacggcccac
      841 tgctttagcg caaaagcaga gtgagcctac cagagttacg cttactgatc catgaaaaat
      901 actgtaaaaa taaacagtgt tgatttaatc aacgctgatt gcctgcattt tattcagtcc
      961 ctgcctgatg attccattga cctgattgtt accgatccgc cttacttcaa ggtgaaaccc
     1021 aacggttggg acaatcagtg gaaaggggac gaagattacc ttaagtggct ggaccactgt
     1081 ctggcccagt tctggcgggt gttgaaacct gccggaagcc tttacctgtt ctgtgggcat
     1141 cgcctggcat ctgatattga gatcatgatg cgtgaacgtt tcaacgtgct taaccatatc
     1201 atctgggcga agccgtccgg acgttggaat gggtgtaata aagaaagtct gcgcgcatat
     1261 tttcctgcca cagagcgcgt tctgtttgct gaacattacc aggggccata tcgtggcaaa
     1321 agtgacggct atgcggcaaa agaaagggaa ctcaaacagc acataatggc accgctgata
     1381 tcgtatttca gtgatgctcg tgccgaactg ggtataacgg caaaacaaat tgccgaagcc
     1441 acaggtaaga aaaatatggt ttcccactgg tttggtgcca gtcagtggca gttgccgaat
     1501 gaggctgact atcggaagtt acaggcactg ttttcccgta tagcggcaga gaagtttcag
     1561 gaacaacaac tggaacaacc acaccaccag ctggtggcat cttatgattc actgaatcgc
     1621 aaatattctg aattgctgga tgagtttaaa tctctccggc gctatttctc cgtatcagtc
     1681 tccgtgcctt ataccgatgt ctggatgcat aaacccgttc agttctaccc gggtaaacat
     1741 ccgtgtgaga aaccggcgga tatgctcagg caaataatca atgccagtag tcgacctggt
     1801 gatctggttg ctgatttttt tatgggatcc ggttccacaa taaaagcagc aatggcgctg
     1861 gggcgtcggg ccttaggtgt tgagcttgag tcagagcggt ttaaccagac agtgaaagag
     1921 ataaacgagc tggtggggaa ataatctggt ggccacgtca ggtggccttt ttatttccat
     1981 tacacagcac ccgcatctgc gaggtggggt tatgaaatcc atggataagt taacaacggg
     2041 tgtcgcctat ggcacctcag caggtagtgc cgggtactgg tttttacagt tgctcgataa
     2101 agtcacgccc tcacagtggg cggcaatagg tgtgctgggt agtctcgtat ttggcctgct
     2161 gacgtacctg acaaaccttt atttcaagat taaagaagat aagcgcaagg ctgcgagagg
     2221 tgaataatgc ctccatcatt acgaaaagca gttgctgctg ctattggtgg cggagcaatt
     2281 gctatagcat cagtgttaat cactggccca agtggtgacg atggcctgga aggtgtcagc
     2341 tacataccat acaaagatat cgttggcgta tggactgtat gtcacggaca caccggaaaa
     2401 gacatcatgc tcggtaaaac gtataccgaa gcagaatgca aagccctcct gaataaagac
     2461 cttgccacgg ttgccagaca aattaacccg tacatcaaag tcgatatacc ggaaacaacg
     2521 cgcggcgctc tttactcgtt cgtctacaac gtgggtgctg gcaatttcag aacatcgacg
     2581 cttcttcgca aaataaacca gggcgatatc aaaggcgcat gtgaccagct acgtcgctgg
     2641 atatacgctg gcggtaagca atggaaaggc ctgatgactc gtcgtgagat tgagcgtgaa
     2701 gtctgtttgt gggggcaaca atgagcagag taaccgcgat tatctccgct ctggttatct
     2761 gcatcatcgt ctgcctgtcg tgggcggtca atcattaccg tgataacgcc atcgcctaca
     2821 aagaacagcg ggataaaaaa gtcagtgagc tgaagcaggc gaccgccacc attactgaca
     2881 tgcagcaacg ccagcgtgct gctgatgtac tcgatgctaa atacacgaag gagttggcta
     2941 atgcgaaagc tgaaaatgat gctcttcggc gcaagcttga taatggtggt cgggtgctcg
     3001 tcaaaggaaa atgctctgtg ccatccgcag ccgaaacttc cagcgcctcc ggcatgggca
     3061 atgatgccac cgtcgaactc tctccagttg ctggacgaaa cgttctcggt atccgggacg
     3121 gaatcatcag agaccagaca gcactgagaa cgcttcagga atatatcagg acgcaatgcc
     3181 ttcgatgata gcgataattt tactcatcat ccttcacatt tggctctgta gacagggtgg
     3241 tgatcacttc tggagtgaat ccagattaaa catctcattg ctgatgcttg aagttgagca
     3301 tctggcgcgc ggtaaggggc tgcgttgaga taagagccag tcattacaaa taccaggatt
     3361 tagcctcgta ttcgcggggc tttttattgc cattacaaaa gccactccct acagagtggc
     3421 tttgataatg gcttataccc tacacgggat aacttaactg atatcccttt taacggataa
     3481 aggtattcaa gcctgacaca tcatgcgctg tatcgtcgcc gtattcccgt attaacagag
     3541 accgtagccc gacggggaac tccttctgcg agagtgtgcg ggaataatca aaaacgatgc
     3601 acaccgggtt tttaccgcgt ttatggttcg cgggtttgtc cctcatgctc gccagtcctg
     3661 tgcgggggtg gaagaaacag gatactcaca cagattcttg tgggcacgat gttattcctt
     3721 tctggattat cccgatgcca ttcatgcaag gcgctgtatc agacgttcgt catggctgtc
     3781 aggctgacgg gtcctcccgg tggggtggtc tgccacgggg cgggagcgtc gcggaaaaag
     3841 gctagttttt gaaatttcat
//
LOCUS       DAFGPF010000223         3779 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.225, whole genome shotgun sequence.
ACCESSION   DAFGPF010000223 DAFGPF010000000
VERSION     DAFGPF010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3779
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.225"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            481..1608
                     /locus_tag="LSX49_005058"
     CDS             481..1608
                     /locus_tag="LSX49_005058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171316.1"
                     /translation="MVEKMKQNSSSTLGALSAPTTWPGANARLLGLGVGLPIAPLDRL
                     AQFSAAEFERFTLEWASEYLAGQQYVNEVQQRGGAGDKGRDIVVWLDPSDAVPRRWHL
                     YQCKHYDANLGLPKAGIEVAKVIYYTFIKDYTVPTQYHFVTHKGVTSPFQDLLDDPTK
                     LKEKMLSEWATFSKQITSKHSVDLTPELEKYIKEFDFSIFHAKQPIEILAEHSKTSFH
                     LMVFGAPLIERDPPTRPPSSVAPIETVYIEQLFSVISADIKTNVRDLVDFQSSISHVK
                     LFERSRITFYCSEGLKELARDQMANQEFFNSLLVEFDDGLYHYTSDLTGTPLLRLKNT
                     VKAAQTLQLGAHPLAIHVTNKDREGICHQLANTNLINWCNP"
     gene            1605..2120
                     /locus_tag="LSX49_005059"
     CDS             1605..2120
                     /locus_tag="LSX49_005059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171317.1"
                     /translation="MSEMQVFEGNFEQRPFNTPLEYGFRALFILDAADNVAMDLQRIV
                     SYDYLLVHTSDVPRGPKSLHPAVPHRGAELLVKRSAIQAGLHLMLSRELIKVVFAAEG
                     ILYQATNLTGRFVRLLMSQYSKELAERASWVTKQFYEYTDEELASYISQNVGQWGSEF
                     DRLTAIDLLDL"
     gene            2122..>3779
                     /locus_tag="LSX49_005060"
     CDS             2122..>3779
                     /locus_tag="LSX49_005060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171318.1"
                     /translation="MLRIRKILLRGNSVQDAYVDFYKGANILAGESDTGKSYLVSCLD
                     YILGAEKLKKKLKEATDYTHLYVEFENDEGGVLTLKRGLEGGKLEAHDVAIQDIHGEG
                     KIIAPVRKGTSKGPDVTSILFPFAGIKEAKLRKNARGETQRFSIRTLAPIFLVDEVSI
                     IDEYSPVTGRSGYDDTARKRMFSYILTGHDDGGVTVEEKPEIVKARLMAKLEFIQDLI
                     RPLDERFSICSPKFPLTSSADDLSDQLIAQAIDEVERAAAAISDLLEGIKMETALTLK
                     IESQLMGVSEIQSRYSLLEERYHSDLKRLDFISEGSHYFTSLQEVPCSLCGQNLLHPH
                     SENAKKLMNSNEVRRSSLAEAAKIHGYLAGLQKAMSDLDRRKEALNIDRYKSKESLDG
                     MKNQIKYTFEPLLTLSKESLDLAIEQRAERDSELNDRQRWFELLKHQKDIEILLEKSS
                     QPRLEWEGLSTRTLAELCREIETVLKDWKWGAEPDVSFNEKEYDIIVDGQPRQSHGKG
                     VRAILYSAFIIGLLKYCIKKGYPHPGLVVIDSPLTSYKKKAAATV"
BASE COUNT         1152 a          732 c          847 g         1048 t
ORIGIN      
        1 tattcttcac tagaggattt ttttgaacca aaagttttgc aaatgaagta taatggaaaa
       61 agcttcgata aaagcaataa tcatgacagt tctactacat ttggaaaaga tagatttgct
      121 acttatatag taagggaaaa tagaaaaact atcgattttt cattattcaa acccatactt
      181 gattcaatta ttgaaatcaa aaaacatttt atcaatctac acccatcaaa gtgatggtta
      241 tgaaaagaga taaaaatgct gatgtcaaaa gaggcttatg ctcggcacag tggagtgagc
      301 tgccaaactg tcgatgactg ggtagccggt ggggcggaag tagttatgtc ccgtagcaag
      361 gttaagattt gctcttgtgt gtggggaacc ttagtcaatt actttcctgg cgcactgtgt
      421 tagattttgt aaaattttaa aagactaaag atttaatatc acttctccat ggaggttgtg
      481 gtggtagaga agatgaaaca aaattcaagt tcgacgcttg gcgcgctttc tgctcctaca
      541 acgtggccgg gtgcgaacgc tcggctgctt gggttaggtg tagggcttcc aatagccccc
      601 ttggatcgtc tggcacagtt tagcgccgcc gaatttgaaa ggtttacact cgaatgggcc
      661 tctgaatact tagctggtca gcaatatgtc aacgaagtac aacaacgtgg cggggcagga
      721 gataaaggca gagatattgt tgtatggctt gatccatctg atgctgttcc tcgaagatgg
      781 cacttatatc aatgcaaaca ttatgatgcg aatttaggcc ttcctaaggc aggcatcgaa
      841 gttgcaaaag ttatctatta tactttcatc aaggactaca cagtacctac acaataccat
      901 tttgttacac ataaaggggt aacatcgcca ttccaagacc tcctagatga tccaactaaa
      961 ctcaaagaga aaatgctatc cgagtgggca actttttcaa agcaaattac atcgaaacat
     1021 agtgttgacc tgacgcctga acttgaaaaa tatattaaag agtttgattt tagtattttt
     1081 catgcaaaac agcctattga gatacttgcc gaacacagta aaacctcttt tcatcttatg
     1141 gtctttggcg caccattaat tgagcgggat ccaccaacta ggcccccatc atctgtggct
     1201 cccattgaaa ctgtatatat tgaacaactc ttttcagtta tcagcgctga tatcaaaacc
     1261 aacgtgcgag atttagttga ttttcaatca agtatcagcc atgtaaaact ctttgaacgg
     1321 tcccgaataa ctttttattg ctcggaaggg ctaaaggaac tcgctaggga ccaaatggcg
     1381 aatcaagaat tctttaattc tttacttgta gagtttgatg atggtctgta tcactacacc
     1441 tctgacctga cagggactcc actccttcgg ttaaaaaata ccgtcaaggc cgctcagacc
     1501 ctgcaacttg gtgcgcaccc acttgccatt cacgtaacga ataaggatcg tgaaggtata
     1561 tgccaccaac tagccaatac aaacttgatt aattggtgca atccatgagc gaaatgcaag
     1621 tatttgaagg aaactttgag cagagacctt ttaacactcc gctggagtat ggatttcgtg
     1681 ctctgttcat attggatgca gcggacaatg tagcaatgga cctacaaagg atagtttcgt
     1741 atgactatct tcttgtgcat accagtgacg tacctagggg gcctaaaagc cttcatccag
     1801 cagttcctca ccggggagca gagcttcttg ttaagcgaag cgcaattcag gcagggctgc
     1861 atttaatgct atcaagagaa ttgattaagg ttgtctttgc tgccgaaggt attttgtatc
     1921 aggctaccaa tttaacagga aggtttgtgc ggcttttgat gtcacagtat tcaaaagagc
     1981 tcgcagaacg tgcctcttgg gtcacaaagc aattctatga atatacggat gaagaacttg
     2041 cttcatatat atctcagaat gtggggcaat ggggttctga attcgaccga ttgaccgcaa
     2101 ttgatctact ggatttataa catgcttcgt ataagaaaaa tactattgcg cggaaacagc
     2161 gttcaagacg cttatgttga tttctataag ggtgcgaata ttctagcagg ggaatctgat
     2221 actgggaaaa gttaccttgt gagttgtctt gactacattc ttggtgccga aaaactcaaa
     2281 aaaaagctta aagaggccac cgattacacc catctttatg ttgaattcga aaatgatgaa
     2341 gggggggtgt taacgctcaa gcgcggtctt gaggggggga aattagaggc acatgatgtc
     2401 gctattcaag acatccatgg agaaggtaaa ataattgctc ctgtgcgtaa aggaacgagt
     2461 aaggggccag atgtgacgtc catacttttc ccttttgcgg ggatcaaaga ggcgaagctt
     2521 cgcaagaatg ctcgtggcga aacgcaacgt ttctcgattc gaacgctcgc tcctatattt
     2581 ttggtagatg aagtatccat tatcgacgaa tactcgccag taacgggacg ttccggttat
     2641 gacgacactg ctcgaaaacg catgttttca tacatcctta ccgggcacga tgatggtggt
     2701 gttaccgtag aggaaaagcc tgaaattgta aaagcgaggt tgatggcgaa gcttgaattc
     2761 atccaggatt tgattcgacc acttgatgaa cgtttctcaa tttgttcgcc caagtttcca
     2821 ttaacgagct cagcagatga tttatcagat caattgattg cacaagcaat tgatgaagtt
     2881 gagagggctg cagccgctat ttctgacttg ctcgagggaa taaaaatgga gacagcgtta
     2941 acgttaaaaa tagaatctca gttaatggga gtatctgaaa ttcaatcgag atatagccta
     3001 ttagaagaac gttaccattc cgacctgaag cggttggatt ttatttccga aggttctcac
     3061 tatttcactt cacttcagga agttccttgt tccctttgtg gacaaaattt actacatcca
     3121 cacagtgaga acgctaaaaa attaatgaac agtaatgaag tccgacgttc ttctttagct
     3181 gaagctgcaa aaattcatgg ataccttgca ggcctgcaaa aagcgatgag tgatcttgac
     3241 cgaagaaaag aagctctgaa tatagacaga tataagtcaa aagaaagctt ggatggaatg
     3301 aagaaccaga tcaaatatac ttttgagcct cttcttacac tttccaaaga aagcctagat
     3361 ttagctattg agcagcgagc tgaaagagac tctgagttga atgatcgaca gagatggttt
     3421 gagttactaa aacatcaaaa ggatatagaa atactgctgg aaaagagcag tcaaccacgg
     3481 ctcgaatggg agggattatc tacccgtacg ctggccgaac tttgtagaga aattgaaact
     3541 gttttaaaag actggaaatg gggtgccgag cctgacgttt catttaatga aaaagagtat
     3601 gacatcattg ttgatggaca acctcggcag tctcacggta aaggtgttcg tgccattctt
     3661 tattcagctt tcatcattgg attactaaaa tattgtatta aaaaaggata cccgcatcct
     3721 gggctagtcg tgattgattc accgctgaca agttataaga agaaagccgc tgctacggt
//
LOCUS       DAFGPF010000224         3657 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFGPF010000224 DAFGPF010000000
VERSION     DAFGPF010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3657
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.226"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(367..1008)
                     /locus_tag="LSX49_005061"
     CDS             complement(367..1008)
                     /locus_tag="LSX49_005061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL7171319.1"
                     /translation="MPANMNRPHHARKTRSCSPEKTARTRQQIARAALEEFSAQGFAR
                     ASISNISKRAGVAKGTVYNYFPTKELLFEAVLKEFIATVRTELESSPRRNGETVKAYL
                     LRVMLPAIRKIDDASTGRARIAHLVMTEGSRFPVIAQAYLREIHQPLQQAMTQLIQEA
                     ASAGELKAEQLLCFPCLLLAPNWFGMVYNEVLNPAAPVSTGDLFEAGIGAFFR"
     gene            1178..1722
                     /locus_tag="LSX49_005062"
                     /pseudo
     CDS             1178..1722
                     /locus_tag="LSX49_005062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680150.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
     gene            1773..2990
                     /locus_tag="LSX49_005063"
     CDS             1773..2990
                     /locus_tag="LSX49_005063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL7171320.1"
                     /translation="MPLSRRNFIQNAVLGISAAGLSAAPALAKNISSSTAHIISKTSG
                     HADTSTNKSLHIISLDRLETSAKDVMTEAAYAYIAHGAGDEWTYHENRRAFSDYPLLP
                     HRLSGVAAHSIDIRTDLLGHHLEHPLLIAPMGAHMFVHPEGEVIAAAGAEKAGALYES
                     SGASNRSLEDIAKASKGPKWFQLYFNADAGVTRSLLERAKAAGYSAIIITADALGPGT
                     SDAFLSMSSPFPAGATFGNHDPRYGGKGDFFNQKVELTPADIEFVKKITGLPVIVKGI
                     LRGEDAVVAIDAGADAIQVSNHGGRQIDGVPSAISQLQEVAARVGHKVPVIFDSGIRR
                     GIDVVRAISLGATAVAVGRPVLYGIAAGGVGGVAGVIEHLKTELRTAMLLSGARTLKD
                     LAQGFIRNKETEH"
     gene            3017..3415
                     /locus_tag="LSX49_005064"
     CDS             3017..3415
                     /locus_tag="LSX49_005064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HBL7171321.1"
                     /translation="MGNYTSALLLLARLMLACLYMISGVPKLLSFTGTIDKMASLGLI
                     FPAITAAIVVLVEIVGALMIVFGFFTRPVSIILCLYTVLASFLGHAFWTMPAELAHGN
                     MIHFYKNICISGGFLALVVSGPGRISVDRR"
BASE COUNT          897 a          829 c          918 g         1013 t
ORIGIN      
        1 gcggacacgg tcatcctcct ctgataaccg tgcctggtgg cagccgcttt taccgcagca
       61 gcggcgcaga gtcgttacag tatcagcacc tgaatctcgc cccacaatcc gctccagtga
      121 ctgctgacag ataaaataca ctgttttatc tgatgcatac gggctgtgac gttattatct
      181 ttccggtagc cctctgcaca aaacagcctt atgcaagggt tgctacatct tgactgcgta
      241 accggcagtg tggtggggcc aggtctttca ggtttaaggc agccaggaga cgttaccggg
      301 tcatggtagg gtatcactgg tatacctcct cctgacggca tggtcataat actgacagtt
      361 atgtgcctat cggaaaaaag caccaattcc ggcttcaaaa agatcgcctg tactgaccgg
      421 tgctgccggg ttcagaactt cgttatacac catgccaaac cagtttggag ccagcaataa
      481 acaggggaag cagagcagtt gctctgcttt taactctccg gctgatgctg cctcctgaat
      541 cagttgggtc atggcttgct gtagtggctg atgtatttcc cgtaaataag cctgagcgat
      601 taccgggaac cggctccctt ctgtcataac caggtgggct attctggctc tgcctgttga
      661 tgcgtcgtca attttcctga tggcaggtaa catcactctc aacagatagg cttttacggt
      721 ttccccgttg cggcgggggg aagattccag ttcagtacgg acggtagcaa tgaactcttt
      781 cagaaccgct tcaaacaata attcctttgt cgggaagtag ttatataccg tgcctttagc
      841 tactcctgcg cgcttgctga tattgctgat gctggcgcga gcgaaccctt gtgcagagaa
      901 ctcctcaagt gctgcccggg ctatctgctg tcgtgtcctg gcagtttttt ccgggctgca
      961 actacgagtc tttcgtgcat gatgaggacg attcatattt gctggcataa atagtggcct
     1021 tctgtgttgt gataaaattg actttgcggt cacttttgat attcttatcc aataagtagt
     1081 gcggtaaggc tgacgtctgc cgctaatatt gaaacagcag catagtatga gcgctatatg
     1141 ctgcccacag attcccagaa gaactgatgg agaatatatg aaacatttta tagcaacagc
     1201 agtcatggca tcatcccttc ttttcggctc taatgctctg gctgcctcat cgtcggcagc
     1261 acagaaggaa agctcacctg aacaatccgg cggtacattc aaatactcca cagtaagatt
     1321 gctactgagc agaagaacgt gtatgacacg ataatcaagt atcagaacgc actgaatgcc
     1381 ggggatacaa aaaccatcct gggcctgttt gctgatgaaa gttattccca gtggaatgat
     1441 aagttgacgg ctgacaatac agaaaaacgc caggggcagt acgatgatct gttcaagcgt
     1501 gaaaagtttg agaccgattt tgcgtttgac tctatctgga tcaacggaga taccgcggtt
     1561 gtccgcactc accaccatgt gggttctgtt gtaacgaact ttaaagagca gaaaaccatt
     1621 attgacctga accgtgaagt ttttgtcctc agtaaaatta atggtgaatg gaaaattttc
     1681 ctttatacct tcaacaccaa cccgcttcag ggcgtggcat gattattata agccagggag
     1741 acctggctta tttataatat atggagctta ttatgcctct ttcccgacgt aattttattc
     1801 agaatgccgt tttaggaata tctgccgcag ggctgtcagc tgcaccggcc cttgccaaaa
     1861 atatctcatc ttcaacggca catatcatca gtaaaacgtc tggacatgct gatacatcga
     1921 ccaacaaatc tcttcatatc atcagtctgg acagactgga gacttcagca aaagatgtga
     1981 tgacggaagc tgcgtatgca tatattgctc atggtgctgg agatgagtgg acgtatcatg
     2041 agaaccgcag ggcattcagt gattatcctt tgttacctca ccgactcagt ggagttgctg
     2101 cccacagcat tgatatccgg actgaccttt tgggccatca tctggaacat cccctgctga
     2161 tagcacctat gggcgcgcat atgttcgtcc atccggaagg ggaggtgatt gctgcagcgg
     2221 gtgcagaaaa ggccggggca ctttatgaat catcaggggc atccaaccgc tctctggagg
     2281 atattgcaaa agccagtaaa ggacctaaat ggttccagct gtattttaac gcggatgccg
     2341 gtgtgacccg aagtttactg gagcgtgcaa aagcggcagg ctattcagcc attattatca
     2401 cagcggatgc gcttggtccc gggacaagtg atgcttttct cagcatgagc tcgcctttcc
     2461 ctgcaggagc gacgttcggt aatcatgacc cccgttacgg tggcaaaggt gattttttta
     2521 accaaaaagt tgagctgacc ccggctgata ttgagtttgt aaaaaaaatc accgggctgc
     2581 cagtcattgt caagggcatc ctcaggggtg aggatgcagt ggttgccatt gatgcaggag
     2641 cagatgccat ccaggtgtct aatcatggtg gtcgccagat tgatggtgtt ccttctgcca
     2701 tcagccagtt gcaggaagtt gctgcaagag tcgggcacaa agttccggtc atttttgaca
     2761 gcggtattcg cagggggatt gatgttgtaa gggctatctc tcttggggca acggctgttg
     2821 cggtcggacg tcctgttctt tatggcatcg cagcaggtgg tgtcgggggc gttgccggtg
     2881 tcattgagca cctgaagacg gaactgagga cggcaatgtt actgagtggt gctcgtacac
     2941 ttaaggattt ggctcagggc tttatcagaa acaaggagac tgagcattga tagtggataa
     3001 aatcaggtat tttaatatgg gaaattacac gtcggcattg ttgctccttg cccgtctgat
     3061 gctggcatgc ctttatatga tatccggcgt tcccaagctg ctatcattca ctggcactat
     3121 cgataaaatg gcctctcttg ggcttatatt tccggcgatt actgcagcaa tagtggtcct
     3181 tgtcgaaatc gttggagcat taatgattgt ttttggtttt ttcacccggc cagtgagcat
     3241 tattctgtgc ctgtataccg tgcttgcttc atttcttgga cacgcattct ggacgatgcc
     3301 agctgaactt gcacatggaa atatgatcca tttttataag aatatctgta tttcgggtgg
     3361 ttttcttgcc cttgttgtat cagggcccgg acgaatctcc gtcgacagac gctgagtttc
     3421 agtaaattag caagcgtagc gtaacagata tcatagcaaa caggtatgta cgtcgccggg
     3481 catggatgtt gtttattgat tgtattccta aaccacctca tggggtggtg gtgattgctc
     3541 ttgttagtag gtatctatcg gtcaactcca atatggtatt tataaaatct ttaaataagt
     3601 ttaattaatt gtattctgta tctaccataa aatagtcgga ataagataaa gccaggc
//
LOCUS       DAFGPF010000225         3480 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.227, whole genome shotgun sequence.
ACCESSION   DAFGPF010000225 DAFGPF010000000
VERSION     DAFGPF010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3480
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.227"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            247..483
                     /locus_tag="LSX49_005065"
     CDS             247..483
                     /locus_tag="LSX49_005065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL7171322.1"
                     /translation="MVKLALQPRDSVACIAREHDINDNLLFKWLRLWLIKGRISRRLP
                     VTNSSGIGVELLPVEMTLDERPYPVFTRGNYEDQ"
     gene            complement(683..1558)
                     /locus_tag="LSX49_005066"
                     /pseudo
     CDS             complement(683..1558)
                     /locus_tag="LSX49_005066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011815933.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            complement(1837..2087)
                     /locus_tag="LSX49_005067"
                     /pseudo
     CDS             complement(1837..2087)
                     /locus_tag="LSX49_005067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2175..3419)
                     /locus_tag="LSX49_005068"
     CDS             complement(2175..3419)
                     /locus_tag="LSX49_005068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7171323.1"
                     /translation="MLQIKARTKILALFCAMSFLMYVDRVNLSATAGLIKDELGLSNT
                     ELGVIFSAFAYTYAVFQIIGGWFVDRLGSRRMIIFCGIIWVIATMATGFVGGFISLFL
                     ARLLLGVGEGAALPSQARAITYWFKPQQRGFVQGVTHSFSRLGNAITPPIIVALVAFW
                     SWRGAFISLAIVTFIWLISWIISYKDDPRDHSGMTEEELEGVPIFEKKDLKVKAEPTP
                     WRALIKRMGPTMGVYFCYGWTSWLFFTWLPTFFMHGRGMDLKSSALFTAGVFLSGVVG
                     NTVGGVISDKVLKMTGNLVAARRNVILFSFISVLFLLVPVINTDSLLIMTICLSVAFF
                     CLELTIGPIWAVPMDITPKYVGIASGLMNAGSAVAGIISPIVFGIIIDKTGNWSLPFY
                     GSVALLIIGIFLTFFMRPDKSL"
BASE COUNT         1049 a          830 c          744 g          857 t
ORIGIN      
        1 ctggtcacaa tttcagattt tttccagtat ctattttccg attcgttcgg cggtaatcca
       61 ccgttatatt catgaggccg gagtgcacta taaaagtgta tgcgtaaacc gactgctgta
      121 tgtagccatt aagcctgtat tggtaacata ggtacccacc ttttcaacaa gtggacacct
      181 gttatagaac aaaaaacatt atcagcagaa ccccgcaggt cattttcaaa tgagtttaaa
      241 cttcaaatgg ttaaactggc tttacaacca agggattctg ttgcctgtat tgcccgggag
      301 cacgatatca atgataatct tctgttcaaa tggctcaggc tctggctgat caaagggcgt
      361 atatcacggc gtcttccggt aacgaactct tctggcattg gcgttgaatt attacctgtg
      421 gagatgacgc tggatgagcg gccttacccc gtttttacgc gaggtaatta tgaagatcaa
      481 tgactagccg tcgaaccgtg tgcatgaact gctgtactga aacttctcag ctgtaaaata
      541 atccttacgc tacgtacttc tcggagcgct tacgattaat cagatgcagt cctaactgga
      601 agaaagaaaa atggagaaaa taagaggaat taatatcctc cacgttcctg aaatcctgga
      661 ggatattaat gtcatcaaaa tattagcgaa cgataatccc taacaaaata cccagtgcgc
      721 caaagtcagc atcactgaag gtggtgttag caaaaccaat atcacccagc acaggcaata
      781 agaatactga caggaaggta ataagcaagc cttgcgcaaa ggcacccaaa atcgcaccac
      841 gacgtccacc cgttgcatta ccgaataccc ctgcagctgc acctacgaag aagtgcggca
      901 ccacaccagg aataatcacg atcatgttca gcagatacaa cgtgaacata ccgattaaac
      961 ctgcagcaaa gctactcagg aaaccaacca gtacagcgtt aggtgcgtaa gggaagatga
     1021 ccgggcaatc gagagcaggt ctggcattcg gaaccagctt gtctgaaata cctttgaatg
     1081 ccgggacaat ctccgcaatc accatgcgca caccctgcag aatgatgtac acgccagctg
     1141 cgaaggtaat ggattgcatg atagagaaca tgaaccagtt tttaccaccg ctaagctctt
     1201 tcaccgcatc tgcacccgca aacaggcacg tcagcaggaa aattatgatc atggtaaaag
     1261 agatagcaac cggcgtgtcg cgcaagaaca gcagactttt cggcacattc atgtcttcag
     1321 tcgagtgctc tttattacca aacttgctgc cgatgaaacc ggccaataca taagataatg
     1381 ttgagaagtg gccgatggca acgtcatcag aaccggtcac tttcttcatg tacggatgag
     1441 caatagccgg gaaaaagacc attgccacgc caacaaccaa agagccaacg gctataagcg
     1501 taatgccggt catgcctgct gttgccagaa ttaccgctac catcatcgac ataaacaacg
     1561 cccgcagcat gagaatggac aatagacatt cgggaggatt ttttcatata aatctccttg
     1621 ctcattttta atgaacgaag gaggagacga cggagaaatc accttcctga acgggatcaa
     1681 gctaccactg tcggatccgc cacactccct gaaccatgtt ttttaagggt cataccacca
     1741 aaaggtcgac ggctgcttcc ttcgctatat tagactgcca gttttaccgg ggagtttctg
     1801 agactcggga cggggtttca cacatggaaa gttttttaat atttcgtttt ccatttcaat
     1861 tcgttgtagc tttttcttta gctcacgtag tttgatttgt tccggtgtta tcagggaggc
     1921 ttttggcgtt taccctgacg ctcatcacgc agttgtttga accattccgt catcgtggaa
     1981 agaccaacat ccatagcctt agcagcgtca gaaacagtgt aattttgatc gacaaccaac
     2041 tgagcggatt cacgtttgaa ttcaggactg aaatttcttc ttttcatagg tgcacctgtg
     2101 ttgttctaag gtgagcatat caccctgttc agatggccaa attcagtaga ccacttcagc
     2161 cctgaattcg acttttacaa tgacttatct ggacgcatga agaacgtcag aaatatacca
     2221 ataataagca atgcgacgga accgtagaat ggtaaactcc agttgcctgt tttgtcgata
     2281 atgatgccaa agacgatagg tgaaataatg ccggcgacag cggaaccggc gttcatcaat
     2341 ccgctggcaa ttcccacata cttcggcgta atatccatcg ggacggccca gataggccct
     2401 atggtcaact caagacagaa gaacgccaca ctcagacata tagtcataat gagcaacgag
     2461 tcagtattta taaccgggac gagcagaaat agtacggaga taaagctgaa aagaatgacg
     2521 ttacgccggg ctgctactag attgccagtc atcttcagca ctttgtcgct gattacgcca
     2581 ccaaccgtat tacctactac accggacaga aatacgccgg cagtaaagag cgccgatgac
     2641 ttaagatcca tgccgcgacc atgcataaag aaagttggta accaagtaaa aaacaaccaa
     2701 cttgtccatc cgtaacagaa ataaactccc attgtcggtc ccattcgttt tatcagggct
     2761 ctccatggag taggctcagc tttaactttt agatcttttt tctcgaaaat tggtacgcct
     2821 tctagttctt cttcggtcat accgctgtgg tctcgtgggt catctttata cgatatgatc
     2881 caagatatta accagataaa tgtgacaata gccaaactga taaatgcgcc acgccaagac
     2941 caaaatgcca ctaatgcaac aataatgggg ggagtaatcg catttcccaa acgagagaat
     3001 gagtgcgtaa cgccctgaac aaagccacgc tgctgcggct tgaaccagta ggtgatcgct
     3061 cgcgcctgag aaggcagcgc cgcaccttcc cctacaccta atagcaatct ggcgaggaat
     3121 agtgatataa agccaccgac gaaaccagtc gccatggttg ctataaccca aataatgcca
     3181 caaaaaatga tcatgcggcg tgagccaagt cgatcaacga accagccacc gatgatttga
     3241 aaaactgcat aggtataagc aaaagcagaa aaaataacgc cgagttctgt attactcagt
     3301 ccgagttcat ctttaatcaa ccccgcagta gctgataagt ttactcggtc cacatacatt
     3361 aggaatgaca ttgcgcaaaa tagcgcaagt atcttggttc tggcttttat ttgtaacatt
     3421 tttgtctcct aaactagcgt taaattgcta gtaaataatg tcaattagtt acatatatta
//
LOCUS       DAFGPF010000226         3476 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFGPF010000226 DAFGPF010000000
VERSION     DAFGPF010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3476
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.228"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1..518
                     /locus_tag="LSX49_005069"
                     /pseudo
     CDS             1..518
                     /locus_tag="LSX49_005069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            complement(574..1452)
                     /locus_tag="LSX49_005070"
     CDS             complement(574..1452)
                     /locus_tag="LSX49_005070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008786839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HBL7171324.1"
                     /translation="MKLKMQDLRLFNIVFESDPGWILDFSNRTLSAFFDEELNIDIDD
                     ERYQKEGTSKAKRVRCLLKQVDRETALRVLGALWQYKTESMPEQAEQSRNDYLALISR
                     LENADTDEAKGVKPVQAWHGVDWHSLIAEMNEMKSLPPHPRGFRFEAWLAELFSIFKL
                     APRSSFRNTGEQIDGSFRLNDEFYLMEAKWHQKRTSAADLHVFEGKLSTKATWTRGVF
                     ISWMGFTPEGLTAFGKGKRVICVSGYDLYHSLNHRIPLPDLLDAKTRHAAETGEPYAE
                     FGRLYALKDKQFGTLK"
     gene            complement(1780..2511)
                     /locus_tag="LSX49_005071"
     CDS             complement(1780..2511)
                     /locus_tag="LSX49_005071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HBL7171325.1"
                     /translation="MNQPIHNAYWLSRFDILLDSALAQHRAVSLIRVDLRFPEYMPVT
                     IMDPDPDSAVISRFFASLKAKIQAYQRKKRCANQRVHATSLRYFWCREFGKEKGRKHY
                     HVILLLNKDTWCSPGDFTVPSSLATLIKLAWCSALHLEPWQGNGLVHFSRRTPFRKPT
                     SSDARPSSDDTPLSGGCSETRKASDKKPGGSAVLWVKRGDVEAMQKARNRASYLVKYE
                     TKQHDGSGQRNYGCSRGLGRLLDGR"
     gene            2616..2864
                     /locus_tag="LSX49_005072"
     CDS             2616..2864
                     /locus_tag="LSX49_005072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020236933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171326.1"
                     /translation="MIETEQTIPERKDNPAHSSKTRNNSMNGFKNDMDDEKSLKGKGS
                     TEHSNKTPETQPERFLAMQINNNTKTYSLTTQLNHRAE"
BASE COUNT         1047 a          847 c          765 g          817 t
ORIGIN      
        1 gatgtagcag ccagttactt ctctggcgca agcaatacca ggagggaagt cttactgcgg
       61 tgactgctgg ggaacagatc gttcctgcct ctgaacttgc tgcagccata aggcagatta
      121 aagaacgcca gcgcctgccc ggaacaaaac gatggaaaat gaactcatta aagaagccgt
      181 tgaatatgga catgcaaaaa gtggatagcg cacgctccct tattgccggg gtgatgcact
      241 gggcggtcac taccggcggc ttcaacagtg aaacagtaca ggacgtcatg ccaggagcgg
      301 tggaacgccg cttcggcaac gagcttccgg cgtctccagt ggagtggctg acagataatg
      361 gttcatgcta ccgggctaat gaaacacgcc agttcgctcg gatgttggga cttgaatcga
      421 agaacacggc ggtgcggagt ccggagagta acagaatagc agagagcttc gtgaaaacga
      481 taaagcgtga ctacatcgtt ttcatgccca agccagaccc tgtacacgat tctgtgtgaa
      541 acaacgggga gcaggtcatc gcttcccaac ccgttatttc agcgtgccga actgtttgtc
      601 tttcagtgca tatagtcggc cgaactcagc atagggctct cccgtttcag ccgcgtgccg
      661 ggttttagca tccagaaggt cgggtaaagg gatcctatga ttcagtgagt ggtaaagatc
      721 ataaccactg acacagataa cccgcttccc tttaccaaaa gccgtcaggc cttcaggcgt
      781 aaaccccatc caactgataa aaacaccgcg tgtccaggtt gccttggtac tgagctttcc
      841 ttcaaataca tggaggtcgg cagccgacgt tcttttctga tgccactttg cctccatcag
      901 gtaaaattca tcattcagtc ggaaacttcc gtcaatctgt tcgcctgtat ttcggaaaga
      961 cgaacgagga gcaagcttaa agatactgaa cagttcagca agccaggctt caaaccgaaa
     1021 accacgtgga tgtggcggca gagatttcat ctcgttcatt tcagcgataa gtgaatgcca
     1081 gtcaacacca tgccatgcct ggacaggctt aacgcctttg gcttcatcgg tgtcagcgtt
     1141 ttctaagcgg gaaatcagtg caagatagtc attacggctt tgttcagcct gttcaggcat
     1201 ggattccgtt ttatactgcc agagcgcacc aagaacccgc agagcggtct cacgatcaac
     1261 ctgtttcagc aagcatctaa ctcgtttggc ttttgacgtc ccctctttct gataacgttc
     1321 atcatcaata tcaatgttca attcttcatc gaaaaaagca gacaaggtgc ggttagagaa
     1381 atccagtatc cagccaggat cgctctcgaa cacaatatta aacagcctca aatcctgcat
     1441 tttaagtttc acgcctacct ccttttttca cagtataacg ggatgaaagt gggggaggaa
     1501 atgagtcaga acctgtacac cagcattagg ggattccgcg tctggtacaa agcagactat
     1561 gagaagagag acgctataac atttgagtcc taccaatcga tctgttcatt tctatgaatg
     1621 gcagtaaatg caaataacca gaacaaccaa aggtttttcg acttatgtgt cacgaacgga
     1681 agtagatggc aatccattgc attacttcag gacgactttt cagaaagcga gctaagggcg
     1741 ttggcataaa ctcaggcatc ggatgctgtt ttacagggtt cacctgccat ccagtagacg
     1801 ccccagccca cgactgcaac cataattacg ttgcccggaa ccgtcatgct gcttcgtctc
     1861 atatttcacg agataactgg ctctgttccg ggctttctgc atcgcttcca catcaccacg
     1921 cttgacccag agcacagcgg atccacccgg ctttttgtct gaagccttcc tggtttcaga
     1981 acatccaccc gacaaaggcg tatcatcgga agaagggcga gcatcagatg atgtcggttt
     2041 acggaaaggc gtccgcctgg aaaaatgaac cagtccatta ccctgccagg gctcaagatg
     2101 cagagcacta caccatgcca gcttgatcag tgtcgccagc gaagaaggaa cggtgaaatc
     2161 ccctggcgag caccaggtat ctttgttgag cagtaatatc acgtgataat gtttcctgcc
     2221 tttttccttg ccaaactccc ggcaccagaa ataacgcagg ctggttgcat gcacacgctg
     2281 attggcacat ctttttttcc gctggtaagc ctgaattttg gctttcaggg atgcaaaaaa
     2341 acgagaaatc accgctgaat ccggatcggg atccatgatg gtgacaggca tatactcagg
     2401 gaaacgtaaa tccactcgga ttaacgagac ggcacggtgc tgcgccaggg cactgtcgag
     2461 aaggatgtca aaacgggata accagtaagc attgtgtatt ggttgattca tgatgagaga
     2521 tctccgttga tttggattga cttcacatca ttcatcaacg cggtaaaact ttacggcatc
     2581 cggcattgag caatgctaca actctctgat taagagtgat tgaaacggaa caaaccatcc
     2641 cggaacgaaa agataatcct gcacacagca gcaaaacacg caacaacagc atgaatggat
     2701 ttaaaaacga catggacgac gagaaaagcc tgaagggaaa aggatccaca gaacattcga
     2761 acaaaacacc agaaacgcaa ccagaacgct tcctggcaat gcaaatcaac aacaacacca
     2821 aaacctacag cttaaccaca caactcaatc acagagccga atagcgcact taaaacctgt
     2881 ttacagataa ccctgccaca agaacaaaaa ccaccaatat cagaatcgat tttcttatcc
     2941 tgaaaacgtt acttttcaac acaccataaa aacgattaac catcgataac gtaaatctca
     3001 tctgaatcaa aacaccagaa ccaatcatca cgctttttct gaaaagagcc ttatgataaa
     3061 gataatcacc ttgcactgag aaaaaacacc agggccagtt aatcatctca tcaatctcat
     3121 cgtcacaaaa tcatccatag aaccatttaa caaaatcgtc gcaagcacac cgtaaatcac
     3181 accaggttat ctcagtcgga tttgcgtttt tacataaaga cacttgtttc agattaacga
     3241 tctaaaacac gaaaactcag aaaaggttaa acgtaacttc agcaaaatag aatgccatct
     3301 tgattgctta aacaggaaag attgttttgt ggcagcatta aactgatttt aattttcgta
     3361 aacacaggag taacaatttt accaaactgg atgtgtatca gacaaagcaa tgtgtattgt
     3421 aatgtttaat gaaaacactt ttagaagtgt ttatgaaaat acgtgtatgt ctggta
//
LOCUS       DAFGPF010000227         3447 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFGPF010000227 DAFGPF010000000
VERSION     DAFGPF010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3447
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.229"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            667..1455
                     /locus_tag="LSX49_005073"
     CDS             667..1455
                     /locus_tag="LSX49_005073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000816189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171327.1"
                     /translation="MKQYKGGYNVNRYDWKNKTTEHLLNDNNLADNHIPEWIRKNEIA
                     AFWFWLIMSHTVPEKLKLNNESEFNSALKGVIVMKDNPMTIIPSSHETRLNVIGKWIN
                     ALILYGEADRIISIMHQNWLGLEKRNEAKWLKKNTEQLKWAWEYIDARISPTYLSWFN
                     PVNDNERYIAIVVLLKMLFPTDTPCLLTPKEFHLGFAAKERFFDKMHNAFRKQFIDGK
                     KDKRVQINVKISPSAKSALDRLTRERKTTQQAILEQLILYGRLD"
     gene            complement(1452..2402)
                     /locus_tag="LSX49_005074"
     CDS             complement(1452..2402)
                     /locus_tag="LSX49_005074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171328.1"
                     /translation="MASLSINTLRRMSICKSQAWKDTQRILKRSGLVYRGERSESFDP
                     EKHFNRYTVRYLYLLNIIALKIRSVSKFSCWIEVGQCHRMTGKHLSLNAPPFMLIPRS
                     IRRKVDGFRQSKGEATPKSAQPFTGSLYEVLSKESDSAKLDAWIAELPLNLQEEGKEI
                     SVMGFSPRAVARPVLRSASPTFELFYQEYQSLRLKSVFKFEPRFEQLLTRLSFRKQSI
                     LRKQQYRVKSQLLERLGNVLFFTSLYNQGCLEEFINALVEKEDIYLKMSPGEEKVKAH
                     QKMVNYIEAFCNKMTEKYLMPAASRHYKKKKIARSESGES"
     gene            2508..3392
                     /locus_tag="LSX49_005075"
     CDS             2508..3392
                     /locus_tag="LSX49_005075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBL7171329.1"
                     /translation="MSFSHSSLSAQVKSYLTFLPEEIRQKILEHLHSVIHYEPVIGIM
                     GKSGTGKSSLCNAIFQSRICATHPLNGCTRQAHRLTLQLGERRMTLVDLPGIGETPQH
                     DQEYRTLYRQLLPELDLIIWILRADERAYAADITMHQFLLNEGADPSRFLFVLSHADR
                     VFPAEEWNATEKCPSRQQALSLATVTARVATLFPSSFPVLSVAAPVGWNLPAFVSLMI
                     HALPPQATSAVYSHIRGENRSEQARKHAQQTFGETIGKSFDDAVARFSFPAWMLQLLR
                     KTRDRIIHLLITLWERLF"
BASE COUNT          970 a          823 c          690 g          964 t
ORIGIN      
        1 gtatcatacc gacattctca atatcttcag acttccatac atactaggtg ttaatttttc
       61 acttttacag ccagcatgga gttttctgtc ctaaaaacag agcagattta ctctggaatt
      121 atttttctgc ccccgtactt caggccccag aaaagacaat ccgaagcaaa ccgtttgtca
      181 acctccatat catcttttac ccccggaaag tgatcgcgtt ttacaaccag aatgacagcc
      241 atactgatta tgtcgtctcc cggccccttc acatataaca tgcatgtctg tcattgctta
      301 ctgctctaca tgacaggatt tcacatacag gatgcgcagt cagtgttttt atcgccacta
      361 taacagacag attactgtcg cttttactct tcagattgtt aatctgacca caagaacagt
      421 cgaacagtac aacgacacac ctaaggagga tatgatccgt agttgatagc atgttttatt
      481 ttattatgaa tagatcaaga aatagttctt gatatgtctg gaatagtttt gtgaatagtt
      541 ctagaatatc cccataatca gctttgaggt gcttgcaggg tgatattttt attgattccc
      601 ttgcatatac aactgacatg tgatggtgaa aatcaccaga aaagaaaacg attgaggcgt
      661 aatcagatga aacaatataa aggcggttat aacgtgaata gatatgactg gaaaaataaa
      721 acaactgagc atttattgaa tgataataat ctggcagata atcacatacc tgaatggatc
      781 agaaaaaatg aaattgcagc attctggttc tggttaatta tgtctcatac agttcccgaa
      841 aaacttaaac ttaataatga atctgagttc aattctgcct tgaagggggt gatcgttatg
      901 aaggataacc ccatgacaat tattccttca agtcatgaaa cacgactgaa tgttataggg
      961 aaatggatta atgcgttaat cctttatggg gaagcagatc ggattatctc aataatgcat
     1021 caaaactggc tgggactcga aaagagaaac gaagccaaat ggcttaaaaa gaataccgaa
     1081 caactgaaat gggcatggga atatattgat gcacgtatct cacccacata tctttcctgg
     1141 tttaatcctg taaatgataa cgaaagatat attgccattg tagttttact aaaaatgtta
     1201 ttccccacag acacaccctg tttactgacg ccaaaagaat ttcacctagg attcgctgca
     1261 aaagaaagat ttttcgacaa gatgcacaat gcattcagaa aacagtttat cgatggaaaa
     1321 aaagataaac gggtacaaat caacgtaaag atatcgccat ccgcaaaaag cgctctggac
     1381 agactgacca gagagcggaa aacaacacag caggctattc tggaacaact gattctgtac
     1441 ggtagactgg attaactttc accactttcg ctcctagcga ttttcttctt tttgtagtgt
     1501 ctgcttgctg cgggcatcag gtatttttcc gtcattttgt tgcagaacgc ttcaatgtag
     1561 ttaaccattt tctggtgtgc tttcaccttt tcctccccag gggacatttt cagataaatg
     1621 tcctcctttt ccacaagtgc atttataaac tcctctaaac atccctggtt ataaagcgac
     1681 gtgaaaaaca acacattccc cagtctctcc agtaattgcg atttaaccct gtattgttgt
     1741 tttctgagaa ttgattgttt tctaaagctc agtcttgtta aaagttgttc aaatcttggt
     1801 tcaaatttaa aaacagattt taatcttagg gattgatact cctgataaaa cagttcaaac
     1861 gtcggggatg ctgaccgaag aacaggtcgg gccacagccc gtggactaaa tcccatgact
     1921 gagatttcct ttccctcctc ctgcaagttc agaggcagtt cagcaatcca tgcgtccagc
     1981 ttagctgaat cgctctcctt gctcaaaacc tcatacaaac tgcccgtgaa cggttgagcc
     2041 gattttgggg ttgcttcacc ttttgactgt ctgaatccat ccacttttct ccggatacta
     2101 cgcggaatca gcataaaagg cggggcatta agagataaat gtttaccagt catacgatgg
     2161 cattgtccca cctcgatcca acaggaaaat ttactaaccg accttatctt aagcgcaatt
     2221 atgttaagca ggtacagata acgcaccgta taacgattaa aatgtttctc aggatcaaac
     2281 gattctgacc gttcccctct gtacacaagt ccactacgct tcagtattcg ctgggtatct
     2341 ttccaggcct gacttttaca aatgctcatt cggcgtagcg tattaatcga cagtgatgcc
     2401 atcactcctc ccgaactttg tcactccaga ttttttcacg cccatattac ctgaatgata
     2461 aaccggatta gtgtgatccg gttcagtgaa atcaacagga taccggtatg tcattcagcc
     2521 attcttccct ctccgcacaa gtgaaatcat atctgacgtt tcttcctgaa gaaattcgcc
     2581 agaaaatcct tgaacatctc cacagtgtta ttcattacga gcccgtgatt ggcattatgg
     2641 gtaaatccgg caccggcaaa agcagcctgt gtaatgccat ttttcagtcc cgtatctgcg
     2701 ccacgcatcc cctgaacggc tgcacccgcc aggctcatcg tcttaccctg caactcggtg
     2761 aacgcagaat gacgctggtc gatctgcccg gcattggtga aacaccgcag catgatcagg
     2821 aataccggac actttatcgt cagctgctac cggaactgga tctgattatc tggatcctgc
     2881 gggcagatga acgcgcgtat gccgccgaca ttaccatgca tcagttttta ctgaatgaag
     2941 gcgcagatcc ctcgcgtttt ctgtttgttc tcagccatgc cgatcgcgtg tttcctgctg
     3001 aagaatggaa tgccacagaa aaatgcccgt cccgtcagca ggcgctctca ctggcgacgg
     3061 tgacagcccg ggtggcaacc ctgttccctt catcatttcc agtactctcc gttgctgcac
     3121 ctgtcggctg gaaccttccg gcgtttgtgt cgctgatgat ccacgcactg ccaccacagg
     3181 caaccagcgc ggtgtattca catatccggg gagaaaaccg ctctgaacag gcccggaaac
     3241 acgcacaaca gacttttggt gaaaccatcg ggaaaagttt tgacgacgcc gttgcccgtt
     3301 tcagttttcc ggcctggatg ttacagcttc tgcgcaaaac ccgggaccgc attatccacc
     3361 tgctgatcac actgtgggag cgtctgttct gacacactca cgccgacagg atgtgtcgct
     3421 ggattaacga gcattcttct ttttatg
//
LOCUS       DAFGPF010000228         3389 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFGPF010000228 DAFGPF010000000
VERSION     DAFGPF010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3389
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.230"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            149..2146
                     /gene="betT"
                     /locus_tag="LSX49_005076"
     CDS             149..2146
                     /gene="betT"
                     /locus_tag="LSX49_005076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004119118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HBL7171330.1"
                     /translation="MSENDTIPKKSTSQINKAVFFTSALLIFLLVAFAAVFPDVADKN
                     FKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAML
                     FSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA
                     LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQ
                     VNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLAL
                     VLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLSWS
                     PFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNQGATGLANTV
                     QQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLASGGVANTPVW
                     QRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGLLKALRRDLTKR
                     ESLSMATIAPTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAMTLVQEELNKQG
                     TISHISDAVDDRIRLEVDLGNELNFIYEVRLRGYISPTFALAAMDNDEQQTEQHRYYR
                     AEVYLKEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR"
     gene            2209..>3389
                     /locus_tag="LSX49_005077"
     CDS             2209..>3389
                     /locus_tag="LSX49_005077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2254 domain-containing protein"
                     /protein_id="HBL7171331.1"
                     /translation="MISRWKWMLKQTIKKLWFRATLFAIVAIITALLSILFKSMIPES
                     VSVKVGAEAVDNILNILASSMLAVTTFSLSIMVTAYGSATTNVTPRATRLVVEDVTTQ
                     NVLATFIGSFLFSLVGIIALNMGAYGERGRVILFIVTLVVIALILITLLRWIQHLTSL
                     GRVGETTAQVEQAAIETFIARARNPCLGGYPWLENNEQPKGTVAVYPKKIGYVEYIDM
                     VKLSKLLTNDPRHVYLVAQPGSFIHPSMPVLYLSQGQESSINTDLLETIIVSDARSFA
                     QDPRFCLSVMAEIACRALSPAVNDPGTAIDVIGRGVRILSTYAQNKSDEIEVKYPSVH
                     VAPLQNNDLLEDFFSPVARDGASMREIQIRVLKGLSMLSKGWPEIFAEAAHTLAFETL
                     E"
BASE COUNT          796 a          788 c          860 g          945 t
ORIGIN      
        1 gaacaaatgg tagtgtccgc tattgccagt acacctcaac attccaccat gcattccgat
       61 taacgccgca tagccagttg aactttgcta ctttgtgaga ggtagtacct tctatccagt
      121 gcgaatttaa ttaatggaat aaatgattat gagtgaaaat gatacaatcc caaagaagtc
      181 tacaagtcag attaacaaag cggtattctt tacatctgct ttgctaattt tccttcttgt
      241 cgcctttgcc gccgtattcc cggatgtcgc cgacaaaaat tttaaactac ttcagcaaca
      301 aatcttcacg aatgccagct ggttctacat ccttgctgtg gccctgattt tactgagtgt
      361 cacgttcctt ggactctcac gctacggtga tatcaagctg ggcccggacc atgcgcagcc
      421 tgatttcagc taccactcct ggtttgcgat gcttttttcg gcagggatgg ggatcggcct
      481 gatgttcttt ggcgttgccg aacctgtaat gcattatctt tcgccacccg ttggcactcc
      541 agaaaccgtt gcggcagcta aggaagcaat gcgtctgacc tttttccact ggggactgca
      601 cgcatgggca atttatgcca ttgtggcgct gattctggcg ttcttcagtt accgtcacgg
      661 tctgccttta actctgcgct ccgcactcta tcccattatt ggcgatcgca tatacggacc
      721 tgtaggacat gcggttgata ttttcgctgt tataggcacg gtctttggcg ttgcgacatc
      781 actgggttac ggtgttttgc aggtgaatgc cggtttgaac catcttttcg gggtgcccat
      841 caatgaaacg gtgcaggtaa ttctgatcgt ggtcatcacg gggttagcga cgatttcagt
      901 ggtgtccggt ctggataagg gaatacgtat cctgtctgaa ctcaatctgg gtctggcttt
      961 gttgctcctg gcgctggtcc tgtgtctggg accaaccgtg cttctgctga agtcatttgt
     1021 ggaaaatacg ggcggttatc tttcggaact ggtgagtaaa acgttcaacc tttacgcgta
     1081 tgagcccaag tcgagcaact ggctgggggg ctggacatta ctgtactggg gatggtggct
     1141 ttcatggtcg ccgtttgtgg ggatgttcat cgcacgggtc tcccgcgggc gaaccattcg
     1201 cgagtttgtc accggcgtgc tgtttgttcc cgcgggtttt acgctaatgt ggatgacggt
     1261 gtttggtaac agcgcgatct atctcattat gaaccagggg gccacaggcc tcgccaatac
     1321 tgttcagcag gatgtggcgc tggccctgtt taatttcctg gagcatttcc cgttctcttc
     1381 tgtgctgtca ttcattgcaa tggcgatggt catcgtcttc tttgtaacgt ctgctgattc
     1441 gggggcaatg gttgtggata ctctggcatc aggtggagtg gcaaacacac ccgtctggca
     1501 gcgaatattc tgggcctcgc tcatgggcat tgttgcaatt gcgcttctcc ttgccggagg
     1561 gctaagtgcg ctgcaaacgg tgacaatagc gagtgcattg cccttctcag tgatcttact
     1621 aatatctata tacggacttt taaaagcttt gcgccgggat ttgaccaagc gtgaaagcct
     1681 gagcatggcg acaattgctc ctacggctgc acgtaaccca attccttggc agagaaggtt
     1741 acgcaatatc gcgtatctgc cgaagcgatc tcttgtgaaa cgttttatgg acgacgttat
     1801 ccagcccgcc atgacgctgg ttcaggagga actgaacaag caggggacga taagccacat
     1861 tagtgatgca gtcgacgatc gtattcgtct tgaagtcgat ttgggcaacg agctgaattt
     1921 tatatatgaa gtgaggcttc gcgggtatat ctcaccgacc ttcgcgctcg ccgcaatgga
     1981 taatgatgag cagcagactg aacaacatcg atattatcgc gctgaggttt atctcaaaga
     2041 aggcggtcaa aattatgatg tgatgggctg gaaccaggaa cagctgatta atgacatact
     2101 ggaccagtac gaaaaacacc tgcacttcct gcacctggtt cgttaatagc aacatgccgt
     2161 cctgggggcg gcaattatta tcccggccgc aatatgaggg aatgcagaat gatttcacgc
     2221 tggaaatgga tgctgaagca gacaattaaa aaactatggt tcagggcaac gttattcgca
     2281 attgtcgcga taataacggc ccttttatca attcttttta aatcaatgat acctgagtcg
     2341 gtttccgtga aggttggtgc ggaagcagtc gataacattc tgaacatact ggcatcgagt
     2401 atgctggcag tgaccacatt ttcgctgagt atcatggtca cagcctacgg ttcagccact
     2461 actaatgtga ctcccagagc tacgcgttta gttgttgaag acgtcaccac acaaaatgta
     2521 ctggccacct tcatcggttc ttttctcttc agtctggtag ggattattgc cctcaatatg
     2581 ggagcttatg gagaaagggg gagagtcatt ttattcattg tcacactggt tgtcattgcc
     2641 ttaatcctca tcacattgct tcgctggata cagcatttga cctctctggg gagggttggt
     2701 gagacaacgg cacaagtaga acaggcggcc atcgaaacat ttattgcgag agcaagaaat
     2761 ccctgtctcg gcggatatcc atggcttgag aacaatgaac agccgaaagg aacagttgca
     2821 gtttatccga agaagattgg ctatgttgaa tatattgata tggtgaaact tagcaagctg
     2881 ctgaccaatg atccccgtca tgtatacctc gtggcgcagc caggcagttt catacatccg
     2941 tccatgccag ttttgtacct gagtcagggc caggagtcgt caatcaacac cgatttactt
     3001 gagacgatta ttgtctcgga tgcacgttca tttgctcagg atcctcgatt ttgtcttagc
     3061 gtcatggccg aaatagcctg ccgggccctt tcccctgcag tgaacgatcc tggaaccgcc
     3121 attgatgtca ttggcagagg tgttcgtata ctttccactt acgcgcagaa taaatctgat
     3181 gaaatagaag tgaaatatcc ttcagtacat gttgcaccac ttcagaataa cgatctactg
     3241 gaagactttt tctcacctgt cgcgcgcgat ggtgccagta tgagggagat tcagataaga
     3301 gtccttaaag gactgtcgat gctgagtaaa ggttggcctg agatatttgc tgaagccgca
     3361 cataccctgg catttgaaac attagagca
//
LOCUS       DAFGPF010000229         3326 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFGPF010000229 DAFGPF010000000
VERSION     DAFGPF010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3326
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.231"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..230
                     /locus_tag="LSX49_005078"
     CDS             <1..230
                     /locus_tag="LSX49_005078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171332.1"
                     /translation="SGFDEPISAGIEEGFWHSLTQLPDTLQIIVIENKEPPVSIMNKV
                     HYEWFAGEHAMDGERRALIPLPSKNSAILMK"
     gene            complement(1110..1445)
                     /locus_tag="LSX49_005079"
     CDS             complement(1110..1445)
                     /locus_tag="LSX49_005079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171333.1"
                     /translation="MKRAILLVLIAAGLLAGCGEKTPKCSSDDAKNLVGDIARKTIEK
                     GMKLDKDVRISVENVRTISHESDLDIYQCAADLTFTKPDLQNSLPITYRIQKTDEGKG
                     PFYINVTGL"
     gene            complement(1476..1835)
                     /locus_tag="LSX49_005080"
     CDS             complement(1476..1835)
                     /locus_tag="LSX49_005080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBL7171334.1"
                     /translation="MNRKLLALFMAAITLPVAAAQYVKPGAVLTLHPGQNNAEFNINA
                     STGDGSGVCNMEGTAQQIAAGESQKRRWVWNDNASECVAVISELTNGKASIMTRGCEG
                     YCGASAAGAMDGLFNKK"
     gene            complement(1850..2377)
                     /locus_tag="LSX49_005081"
     CDS             complement(1850..2377)
                     /locus_tag="LSX49_005081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171335.1"
                     /translation="MATTITEITECFEYFFSSLYRREFVKTLRLNECSERELLPLVRC
                     YLLGWFADNVSPEVKSKLPGTVSGHGYIDFVIDDVAVEFAVRKPTAARSNVSATVNST
                     EVKKLMKHDGKALLVLFDFSDTPYSEEQIESFRNWPSLGRGNHRKSAFNVVYFFVEKR
                     RPLALGKITKNIRIT"
     gene            complement(2389..2658)
                     /locus_tag="LSX49_005082"
     CDS             complement(2389..2658)
                     /locus_tag="LSX49_005082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL7171336.1"
                     /translation="MRNSTASQKKQIKGSSGNWHRADIVAALHKRGLTLALLSRSHGL
                     APRTLNNALERHYPRAERIIAGALDTTPETLWPERYALKNGPNSR"
     gene            2780..3268
                     /locus_tag="LSX49_005083"
     CDS             2780..3268
                     /locus_tag="LSX49_005083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001543672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171337.1"
                     /translation="MSSKRTVSAIPTHPEASVEEAKDWLTAEEFTHIEGMPGTARGAR
                     MRLEKLASLHPEIRRKRTAGKGVVYHISAATMSLDDERNRAKGEAFTLNDSDRQLSLW
                     VQLYRNMSPASRAQLMEQALRLVKDDLMSQGPNVSELAVQIMKLPEDERKRLFEKLNG
                     KV"
BASE COUNT          861 a          752 c          780 g          933 t
ORIGIN      
        1 tatcgggctt cgatgaaccc atatcggctg gtattgagga aggcttctgg cattcactga
       61 cccaattgcc tgatacctta caaatcatag ttatagagaa taaagaaccg ccggtatcaa
      121 tcatgaataa agttcattac gaatggtttg cgggtgaaca tgcaatggat ggagagcgca
      181 gagcccttat cccgctgccc tcaaaaaata gtgctatttt aatgaagtaa cttaggatgg
      241 gtagccatca aatcgcagtt atacgattgg tggggtttgt aaaagcggta gtcttgatta
      301 ccactgcatt cattctacaa gcacatactt ccctaggttg ctgtagttat ccgattacac
      361 gccttttctg aaagcagcct cagggagccg gataaaaccc gttaaaagtg gcttgcctat
      421 actgctgcgc ggcgctgacg ctttagaggc cccaggattt aggcaaatca atgtagttag
      481 ctcagtagca ggtcatatct gggctataaa tggcattacg tgacactgaa agagcttccc
      541 agtggcatcg tatttggtga gccccaacct acaagacggg cggggatagc cgtgattggc
      601 acccacagca aggcgataaa gatgttcaac ggagcggctc agcaggtatg gggatggtag
      661 gatttagtct tcatatgcct gtggaattaa tcaaccctca gagcccgaca cacccggcat
      721 tgcttacggt ataagactga ttgagaaggt gtttgacgtt tttgtatccc agtctgtcgg
      781 taaagtaaac acagtgatca gtaactggta gtactggaag tgattgcggt cgtaatgctg
      841 attttgcacg ctacgacagg tatattctgt ttggtatctg tagaggttgt gatggcgctg
      901 accttgcaca tgccaggtac gttagactta ataataaagg gagtattagc aggagggatt
      961 ttttcggact cagttgtatt gtgtgtaacg agccaactaa atgtgataat agctataatg
     1021 gtaaatatga tgatcttttt catagggttt ccttttggaa taaaacatga attatttcac
     1081 ccaaaaggaa cccggatgtt attcagtgat tataaacctg ttacgtttat ataaaacgga
     1141 cctttaccct catcagtttt ctgaatccgg taggtgattg gtagagaatt ttgcaaatct
     1201 ggttttgtaa acgttaaatc agcagcgcac tgataaatat ccagatctga ttcatggcta
     1261 attgttctga cattttctac agaaatacgc acatccttat ccagtttcat ccctttctcg
     1321 attgtctttc ttgcaatatc cccgaccaga ttttttgcat catcactact acattttggc
     1381 gttttctcgc cgcagccagc cagcaaacca gcagcaatta ataccagaag tattgctctt
     1441 ttcatctgta gttccttcgt aaattaatga tacttttatt tcttattaaa tagaccatcc
     1501 attgcgcctg ccgcagaagc cccgcagtat ccctcgcaac cacgtgtcat aatgctggcc
     1561 ttaccgtttg tcagttcact aattactgca acacactcgc tggcattgtc attccagacc
     1621 cagcgacgct tctgactttc tccggcagct atttgctgtg ctgtcccctc catattgcat
     1681 acgcccgaac catcccccgt tgaggcatta atgttgaatt cagcgttatt ctgtcccgga
     1741 tgcagggtta gaaccgctcc gggttttacg tactgcgctg ctgcgactgg tagcgttatg
     1801 gctgccatga ataaggccaa cagttttctg ttcattaatt aattccctgt taagtgatac
     1861 ggatgttttt ggtgattttc cccagtgcca gcggtctgcg tttttccaca aagaaataaa
     1921 cgacgttgaa tgcagacttg cgatgattcc ctcgaccaag agagggccag ttgcggaagg
     1981 attcaatctg ttcttctgaa tagggtgtgt cagagaaatc aaacagcaca agcaaggctt
     2041 tgccgtcatg tttcatcaat ttctttactt ctgtactgtt gacggtcgca gagacattgg
     2101 aacgtgccgc agttggttta cgtactgcaa actcaacggc cacatcgtca atgacaaaat
     2161 caatgtaacc gtgcccggat acagttcctg gcagtttgct ttttacttcc ggtgagacgt
     2221 tatctgcaaa ccaacccagc aaatagcaac gtaccagagg cagtaattcc cgctcgctac
     2281 attcgttcag acgcagggtt ttgacgaact ccctgcgata aagagaactg aaaaaatact
     2341 caaagcattc cgttatttca gtgatggtgg ttgccatggt tgcatccttt acctgctatt
     2401 aggtccattt ttaagggcat acctttccgg ccataatgtt tccggtgtcg tatccagagc
     2461 cccggcaata atgcgctcag ctctgggata atgacgctct aaggcgttat ttaatgtccg
     2521 tggcgcaagg ccgtgactgc gtgacagtaa cgccagcgtt aaccctcgct tgtgaagtgc
     2581 tgccacaata tcggcacgat gccagttccc tgaacttcct ttgatttgct ttttctgcga
     2641 tgctgttgag ttacgcacag tattaactcc atggaatcag tacatggata ttaaatgcga
     2701 ataaaagata cctttcaagt tcttttggta tctatttatt ggttttcata ttaacgcatt
     2761 gatatctggt gaaatttata tgagcagtaa gagaacagtt tcggctatac ctactcatcc
     2821 tgaagcttct gttgaagagg ctaaagactg gctgacagca gaggaattca ctcatattga
     2881 ggggatgccg ggcactgcgc gtggcgccag gatgcgcttg gaaaagctgg catccctgca
     2941 cccggaaata cgtcgtaaaa ggactgccgg gaaaggtgtg gtttaccata ttagcgcagc
     3001 cacaatgtcg cttgatgatg agagaaacag ggctaagggc gaagcgttta ctctcaacga
     3061 cagtgatcgc cagctaagcc tctgggtgca gctgtatcgc aatatgtcgc cagcttcgcg
     3121 ggcgcaactg atggagcagg ccctcaggct ggtaaaggac gatctgatgt ctcaggggcc
     3181 caatgtttct gaactggcgg tacaaatcat gaagctgccc gaagatgagc gtaagcgcct
     3241 ctttgaaaag ctgaacggga aggtgtgata gcgtcagttt tccgccatgc cagacagaag
     3301 gaaccacccc ggaatcctga cctgtc
//
LOCUS       DAFGPF010000230         3266 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFGPF010000230 DAFGPF010000000
VERSION     DAFGPF010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3266
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.232"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..382
                     /locus_tag="LSX49_005084"
     CDS             <1..382
                     /locus_tag="LSX49_005084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBL7171338.1"
                     /translation="STWQGVVYVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQALWA
                     RRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAEVI
                     HRKSWKNRKRRLSTVWQILKFLRE"
     gene            411..815
                     /locus_tag="LSX49_005085"
     CDS             411..815
                     /locus_tag="LSX49_005085"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL7171339.1"
                     /translation="MKSLTAVRKKSPNYPVEFKIKMVELSHRPEISVAQLAREHGIND
                     NLLFKWRQYWREGKLRPPSTTENNVPELLPITLDAEDVVPTTSPRSQPVAAATPESLN
                     ISCEVTFRHGSLRLNGAISENILNLLIRELKR"
     gene            1020..1847
                     /locus_tag="LSX49_005086"
     CDS             1020..1847
                     /locus_tag="LSX49_005086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012638432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBL7171340.1"
                     /translation="MMLSSRFRSANILRSDRPLNDDQIMRYAPSIFATEAHESRSDRY
                     AYIATSEVLNGLRDNGFHPFMVCQTRVRNLDKREHTKHMIRLRHAGQINGTEAKEIIL
                     LNSHDGSSSYQMLAGVFRFVCHNGLVCGDTVADIRIPHKGNVTERVIEGAFEVLDQFD
                     NVENHMDAMKSVTLNALEKRIFADAALALRYDEKDGPAPIAASQLLEARRFEDRKDDL
                     WTTFNRVQENIIRGGLSARTKQGKSTRTRAVTGMDKDTSLNRALWILSERMNELKAA"
     gene            1904..2383
                     /locus_tag="LSX49_005087"
     CDS             1904..2383
                     /locus_tag="LSX49_005087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL7171341.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     QTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRKWTDQAGVEKYTTEV
                     VVNVGGTMQMLGGRPQNASQTGNQPQGGQQFSGQPQTTGTAAAAGNEPPPFDDDIPF"
     gene            2447..2752
                     /locus_tag="LSX49_005088"
     CDS             2447..2752
                     /locus_tag="LSX49_005088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015272403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdK family transcriptional regulator"
                     /protein_id="HBL7171342.1"
                     /translation="MAVERISPEEWQRIAPALRTCSQVTIDMAYAVLVDGRKQVDVAK
                     EFDRSKQTVNAAIRRVTAIFNEVIPEDEQLEFVQVWLPPELAKQVKEMAKKHNQNGV"
     gene            2755..3063
                     /locus_tag="LSX49_005089"
     CDS             2755..3063
                     /locus_tag="LSX49_005089"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171343.1"
                     /translation="MSDTHLSLYEFLRMFVVIGVTLIGYFYLILNLITVRKLGGVFQL
                     LALIGLSAIFSFMMFRSENMWSGEPSFSLALMFGSFSATVIFYMFKIMIHAFESLGRE
                     "
BASE COUNT          858 a          776 c          830 g          802 t
ORIGIN      
        1 cagcacatgg cagggggtcg tctatgtggc attcatcatt gatgtgtttg ccggatacat
       61 cgtggggtgg cgggtctcat cgtctatgga aacgacattc gtgttggatg ctctggagca
      121 ggcgttatgg gcccgtcgac cgtccggcac agtccatcac agtgataaag gttctcagta
      181 tgtatcgctg gcctacacac agcggcttaa ggaagccgga ttactggcat caacaggaag
      241 tactggtgac tcgtatgaca acgcgatggc ggagagcatc aatggccttt acaaagcgga
      301 ggtaatacac cgtaagagct ggaaaaaccg taagcgtcgt ctcagcaccg tctggcagat
      361 cctgaaattc ctgagagaat agtggacacc aaatatggtg gacgctatcc atgaaatcat
      421 taaccgcagt gcgtaaaaaa agccctaatt atcccgttga gttcaaaatc aaaatggttg
      481 aactctcgca tcgaccagag atctccgtag cgcaactcgc tcgtgagcat gggatcaacg
      541 ataatttgct gttcaagtgg cgccagtact ggcgcgaagg aaaactacgt cctccttcaa
      601 caacagaaaa caacgtgcct gagctgctcc cgataactct tgatgccgaa gatgttgtcc
      661 ctacaacctc cccccggtca caacctgtag ctgctgcgac acctgaatca ctcaatatca
      721 gctgtgaagt gacgttccgg cacggatcac tccgtctgaa tggtgccatc agcgaaaata
      781 tcctgaacct gctgatacgg gagctcaaac gttgatccca ttaccatatt gagtaccaac
      841 aaagcccgga aaccgggctt ttttcacatc gtagagtaca ataaaaagta aaataaaatg
      901 atacttttag ttgacttgtg ggaggggaaa acctatactg tattcatcgg ttagcaatgg
      961 tgctgaccgg cccggaacca gcggcggcaa ccgctccggg taaatagcga aggagtatga
     1021 ttatgttatc tagccgtttt cgttctgcaa atattctgcg ttctgaccgc cctcttaacg
     1081 atgatcagat catgcgttat gccccgtcta tctttgccac tgaagcgcat gaaagccgct
     1141 ccgaccgtta cgcctacatt gcgaccagcg aagtattaaa tggtttgcgt gataacggtt
     1201 ttcatccatt catggtttgc cagactcgcg ttcgcaacct ggataaacgc gaacacacca
     1261 agcacatgat ccgtctgcgc catgccgggc aaattaacgg caccgaagcg aaagaaatta
     1321 tcctgcttaa ctctcatgat ggcagcagca gctatcaaat gctggccggt gtattccgtt
     1381 tcgtctgcca taacggttta gtctgcggtg ataccgttgc tgatattcgt atcccgcaca
     1441 aaggcaacgt taccgagcgt gttattgagg gcgcttttga agtgctggat cagttcgata
     1501 acgttgaaaa ccatatggat gctatgaagt ctgtcacact gaatgcgctg gaaaagcgta
     1561 ttttcgctga cgcggcgtta gcactgcgtt atgacgagaa agacggcccc gcaccaatcg
     1621 ccgcgagcca gctccttgag gcgcgtcgtt tcgaagatcg caaagatgat ttgtggacaa
     1681 cgtttaaccg tgtacaggaa aacatcatcc gtggcggttt gagtgccaga actaagcagg
     1741 gcaaatcaac ccgtacccgc gccgtaaccg gcatggataa ggatacttct ttaaaccgcg
     1801 ctttatggat tctcagcgag cgcatgaatg aactcaaagc cgcttaatgg caaacgcccc
     1861 gcttgatcgc ggggctttta tcaaccagaa aaaggtgatt atcatggctt caagaggcgt
     1921 taacaaagta attctggtcg gcaatttagg ccaagatcct gaagtgcgtt atatgccgaa
     1981 cggtggcgcg gttgccaata ttacgttagc cacgtctgaa agctggcgtg acaagcaaac
     2041 cggcgagatg aaagagcaga ctgaatggca tcgcgtagta ttattcggca agctggccga
     2101 agtcgccggt gaatatttgc gtaaaggctc gcaggtgtac attgaaggcc agctcagaac
     2161 tcgtaaatgg actgatcaag cgggcgttga gaagtacacc acagaggttg tggttaacgt
     2221 cggcggtact atgcagatgt taggcgggcg cccacaaaac gcttctcaga ctggtaatca
     2281 gccgcaaggt ggccagcagt tcagcggcca gccacaaacc accggcacag cggctgcggc
     2341 aggaaatgaa ccgcctccgt ttgatgatga tataccgttt tgaatgacat aactttctga
     2401 aataacttaa aaaaacggcc ctttacaggg ccgtagtgag gtaaaaatgg cagtagaacg
     2461 catttcccct gaagaatggc agcgcatcgc accggcatta cgcacatgca gccaggtaac
     2521 gatcgatatg gcatacgccg tactggttga cggtcgcaaa caagtcgatg tggctaaaga
     2581 gttcgaccgg tcaaagcaaa cggtcaatgc tgcaatcagg cgcgttactg cgatttttaa
     2641 cgaagttatc ccggaagatg agcagttaga atttgtgcaa gtctggttgc cgcctgagct
     2701 ggcgaagcag gttaaagaaa tggctaaaaa acataatcag aatggagttt aattatgtct
     2761 gacacgcatt tgtctttata tgaatttcta aggatgttcg ttgtaatagg cgtaactctc
     2821 attgggtact tttatctcat cctcaattta ataacggttc gtaaattagg gggggtattt
     2881 cagttactgg ctcttatagg tcttagtgcg atattttcat tcatgatgtt cagaagtgaa
     2941 aatatgtggt cgggtgagcc aagtttttct ctggcgctga tgtttggttc gttttcagca
     3001 acggttattt tttacatgtt taaaattatg attcatgctt ttgagtcgtt aggtagagaa
     3061 taaattatta aatcacttat ggcgttccct ccggggcggg ctttcgtgct gcgcatcgag
     3121 ccaggcaagc tgtctcgccc ctccgggctt caatccctaa cgcaatcaac tgcgctcatc
     3181 ctgatcttgc cggttttctc cggtgcaatc gtgcctgtag gggcgctggc cgctgcgcgg
     3241 ccaacccccc aacacccgga taaatc
//
LOCUS       DAFGPF010000231         3241 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.233, whole genome shotgun sequence.
ACCESSION   DAFGPF010000231 DAFGPF010000000
VERSION     DAFGPF010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3241
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.233"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(20..547)
                     /gene="mobB"
                     /locus_tag="LSX49_005090"
     CDS             complement(20..547)
                     /gene="mobB"
                     /locus_tag="LSX49_005090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBL7171344.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLHFLASRMDTSKL
                     DLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQDG"
     gene            complement(529..1113)
                     /gene="mobA"
                     /locus_tag="LSX49_005091"
     CDS             complement(529..1113)
                     /gene="mobA"
                     /locus_tag="LSX49_005091"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HBL7171345.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQVSGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPHDLAARLTHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMAF
                     MRLAGGHAVDFSDRKEAFINVNTPEELARWQEKR"
     gene            1183..1452
                     /locus_tag="LSX49_005092"
     CDS             1183..1452
                     /locus_tag="LSX49_005092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HBL7171346.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            1529..2515
                     /gene="srkA"
                     /locus_tag="LSX49_005093"
     CDS             1529..2515
                     /gene="srkA"
                     /locus_tag="LSX49_005093"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HBL7171347.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            2532..3158
                     /gene="dsbA"
                     /locus_tag="LSX49_005094"
     CDS             2532..3158
                     /gene="dsbA"
                     /locus_tag="LSX49_005094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HBL7171348.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKELTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK"
BASE COUNT          830 a          778 c          779 g          854 t
ORIGIN      
        1 tgcttcagcc tattcttgct tatccgtcct gcttttgcat ccactccacc acaaaatcag
       61 ccagcccctc aacatcatta atatccagta acgcgacatc aagattaagc ggcacatcac
      121 tggctacagc aataacatgc ctgtctatca ctaattcttc cggtcgatgt ccggctccat
      181 cgcgaaacag cacaatcttt gcgatctctt catgcttaaa cccttcgacc agaatcaaat
      241 ccagctttga ggtatccatt cgacttgcga gaaaatgtag atccagctct tcttcgtctg
      301 gtgtttccgt catcaaggcc catcgctgct ggctggcaac gatggtttgc gccgcgccag
      361 ccttgcgcag ctcatagcta tctttgcccg gtttatcaac atccatatca tggtgcgtat
      421 gcttaatcag ccccggacgg atccctctgg cgcataatgc cgggatcaat tttttcagca
      481 gcgttgtttt tccggtgcca ctccatgcag caaaggcgag taacggtatc atcgtttttc
      541 ctgccatcgg gcaagctcct ctggcgtatt cacgtttata aatgcctctt tacgatcgct
      601 gaaatcaacc gcatgaccgc cagccagacg cataaatgcc ataacccggc gttctcctgc
      661 ttgcagatat tccagtaata aaggctcaat tgcgcggttt accagagcaa tagtcgggtg
      721 atcgcgttca ccgtcgtgga cccacacgac aggcgcatct ttgcgctgat gagtaagccg
      781 ggcggctaaa tcatggggaa tgtaaggcgt atcgcacggg caaaacaaaa accactcacc
      841 cgcttcctgc tgcattactg aaagcattcc tgccagaggg ccagggtaat ccgccagtga
      901 atcttcaatc actttcagac cgcttacctg atagatttcc tgatgacgat tagcattaac
      961 cacgacgtga gaaagctgcg tcataagcgc gtcagcgaca tgttgccata atggtttgcc
     1021 gtttaattca agcaatcctt tatctacgcc gcccattcgt ctggctttac cgcccgccag
     1081 cacaacgcct gttatcgtcg tcatcagatt caccgatatc gcctctttta ttgtgggatt
     1141 gaccctgcta acgtgtctgt ctcaagagta aggagcatta ctatgaaatg taaacgtctg
     1201 aatgaagtta ttgaactcct ccagccagcc tggcaaaaag agccagacct taacctgctg
     1261 caatttttgc agaaactggc gaaagagtca ggttttgacg gcgaactggc ggatttgacg
     1321 gatgacattc tgatctatca cctgaaaatg cgtgattccg cgaaagatgc ggtgatcccg
     1381 ggtttgcaga aagattatga agaagatttc aaaacggcgc tattacgcgc acgtggcgta
     1441 attaaagagt aaaagcttgt aagcggcgca accaaaatca tcgtgaaatg atatccttca
     1501 tcattcgtaa tgttttccgg atgatgggat gaacaacagc gcttttactt tccagacact
     1561 acacccggat accatcatgg acgctctgtt tgagcatggg atccgggtgg attccggtct
     1621 taccccgctt aacagctatg aaaaccgtgt ctatcaattt caggacgaag atcgtcgacg
     1681 ttttgtcgtc aaattttatc gccctgaacg ttggacagcc gatcaaatcc tcgaagaaca
     1741 tcaatttgcg ttgcagctgg ttaacgatga agttccggtc gcagcacctg tggcctttaa
     1801 tggtcagact ttattgaacc atcagggatt ttatttcgct gtttttccaa gcgtcggtgg
     1861 tcgccagttc gaagctgata atatcgatca gatggaagcg gttgggcgtt atttagggcg
     1921 tatgcaccag acggggcgca aacagctttt tatccatcgc ccgaccatcg gtttgaatga
     1981 atatctcatt gagccacgca agctgtttga ggacgctaca ctgatacctt ccgggttgaa
     2041 agcggcattc ctgaaagcga cagatgagct gattgccgcc gttacagcac actggcggga
     2101 agatttcacc gttctgcggc tacatggaga ctgccacgcc gggaatattc tctggcgcga
     2161 tggcccaatg tttgttgatc tggatgatgc acgtaatggt ccagccgttc aggatttgtg
     2221 gatgttgctc aatggcgata aagccgagca gcggatgcaa ctggaaacta ttattgaggc
     2281 ttatgaagaa tttagcgagt tcgacaccgc tgaaatcgga ctgattgaac ctttacgcgc
     2341 catgcgtttg gtttattatc ttgcctggct aatgcggcgt tgggctgatc ccgcgttccc
     2401 gaaaaatttc ccgtggttaa ccggggaaga ttactggcta cgacagacgg cgacttttat
     2461 agaacaggca aaagttctac aagaaccccc tttgcaatta acacctatgt attaatcgga
     2521 gagagtagat catgaaaaag atttggctgg cgctggctgg tttagtttta gcgtttagcg
     2581 catcggcggc gcagtatgaa gatggtaaac agtacactac cctggaaaaa ccagttgctg
     2641 gcgcgccgca agtgctggag tttttctctt tcttctgccc gcactgctat cagtttgaag
     2701 aagttctgca tatttctgat aacgtgaaga aaaaactgcc ggaaggcgtg aagatgacta
     2761 aataccacgt caacttcatg gggggtgacc tgggcaaaga gctgactcag gcatgggctg
     2821 tggcgatggc gctgggcgtg gaagacaaag tcacagttcc gctgtttgaa ggcgtacaaa
     2881 aaacccagac cattcgttca gcatctgata tccgcgatgt atttatcaac gcaggtatta
     2941 aaggtgaaga gtacgacgcg gcgtggaaca gcttcgtggt gaaatctctg gtcgctcagc
     3001 aggaaaaagc cgcagctgac gtgcaattgc gtggtgttcc ggcgatgttt gttaacggta
     3061 aatatcagct gaatccgcag ggtatggata ccagtaatat ggatgttttt gttcagcagt
     3121 atgctgatac tgtgaaatat ctgtccgaga aaaaataatt caatgtaaat aacataaagc
     3181 ccgtgaatat tcatgggctt ttttattatt taataaatat aaatacattc tgataatgcg
     3241 t
//
LOCUS       DAFGPF010000232         3174 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFGPF010000232 DAFGPF010000000
VERSION     DAFGPF010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3174
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.234"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..487)
                     /locus_tag="LSX49_005095"
     CDS             complement(<1..487)
                     /locus_tag="LSX49_005095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL7171349.1"
                     /translation="MTKSETFMIPNHKAAKLSELDMMIVNSVPPGGNWKNIPLDVPSK
                     RIEQIRDSYAQGKGSRSTYYGRLLPDMPAYTINTYFNRPGNGCHIHYEQDRVLSQREA
                     ARLQSFPDDFIFFGGQTAINTQIGNAVPPFLAFLIAKEIEKAIGNTGYYIDLFSGAGG
                     LG"
     gene            complement(480..2120)
                     /locus_tag="LSX49_005096"
     CDS             complement(480..2120)
                     /locus_tag="LSX49_005096"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Alw26I/Eco31I/Esp3I family type II restriction
                     adenine-specific DNA-methyltransferase"
                     /protein_id="HBL7171350.1"
                     /translation="MEEIFYMKHIHLINSLSLDETTKFTKKATGKYYTDPKIALLMIE
                     KLLPLINSCDKKSYNVADPFSGDGRLITLLIKQWMINGFPDVEWNVYLFDIENTGLTY
                     AKNALSELKLAGANINITIKNSDVFYEFKKYVDYFDCVITNPPWENIKPDSRELDFFE
                     PSMKSMYIDSLREFDDYLSRVLPYSQPKRKFAGWGTNLSRVGAELSLEICNKNGLVAI
                     VMPASFFADEQSYILREKFFNSGRIDCINYYPAEAKLFGGADVSSCSFIFNKGESLND
                     NIQLSVYDKNLNIKSLGFFDLSSIDSQYLSIPVSQGVHAVHLLRKLQEGYPTWGSLEK
                     NGEIWAGREIDETGSSDWTQKSGGGLLFIKGKMIGRYNFHNEKSLRITKKIDKVLSNS
                     NFVRIAWRDISRPSQKRRMIATIIPPNSLAGNSLGVVYYKSGSQDSLFSLLGIINSLC
                     FEFQLRSFLATGHVSLSALRKTAIPSEKILLQHSELKQLVISCIEGCCDAELKIEAYV
                     AKNIYKLDLNEFNKLLSSFDKIELAEKESLLRIFQHYD"
     gene            complement(2893..3069)
                     /locus_tag="LSX49_005097"
                     /pseudo
     CDS             complement(2893..3069)
                     /locus_tag="LSX49_005097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          983 a          671 c          506 g         1014 t
ORIGIN      
        1 gtcccagccc tccagctccg gaaaataaat cgatataata accagtatta cctatcgcct
       61 tctctatttc tttcgcaatc agaaaagcta aaaatggggg cactgcatta ccgatttggg
      121 tattaattgc tgtttgacct ccgaagaaaa taaaatcatc cgggaacgat tgtagtcttg
      181 cagcttctct ctgggataga acacgatctt gctcatagtg aatatggcaa ccattcccag
      241 gtcggttaaa atatgtattg atagtatatg caggcatatc tggaagtaat ctaccgtagt
      301 atgttgaacg gcttcctttt ccttgtgcat aactatccct aatttgctct attcttttag
      361 acggtacatc taaaggaata tttttccagt tgccacctgg cggtactgag ttaacaatca
      421 tcatatccaa ttcacttagc tttgctgcct tgtgattggg aatcataaat gtttcacttt
      481 tagtcataat gttgaaaaat cctcaataaa ctttcttttt cagctaactc aatcttatca
      541 aatgaagaca gaagcttatt aaattcattc aaatccaatt tgtaaatatt tttggcaaca
      601 taagcctcaa ttttcaactc agcatcacaa catccctcta tgcaagaaat cacaagttgt
      661 tttaattcag aatgttgtaa taatattttt tcagacggta ttgcagtttt tcgtaaggct
      721 gacaatgata catgaccagt agctaaaaag cttcttaatt gaaattcaaa acaaagggag
      781 tttataatac caagcaaact aaagagcgaa tcttgcgaac cacttttata atagaccacc
      841 cctaatgaat tccctgccaa agagttagga ggtattatcg ttgcaatcat tcgccttttt
      901 tgactcgggc gtgaaatgtc acgccatgca atccttacga aattagaatt ggatagaacc
      961 ttatcaattt ttttcgttat tcttaagctc ttctcattat gaaaattata cctcccaatc
     1021 atttttcctt taatgaataa taatccgccg ccactttttt gtgtccagtc actactacca
     1081 gtttcatcta tttctcttcc tgcccatatc tctccatttt tttccagact accccatgtt
     1141 gggtatccct cttgcagctt tcttaacaaa tgaacggcat gaacaccttg agataccgga
     1201 atgctaagat attgagaatc tatactagac aaatcaaaaa aacctagtga tttaatattt
     1261 aagtttttat catacacact aagttgaata ttatcattaa gggattcacc tttattaaaa
     1321 ataaaagaac atgaagaaac atcagcaccg ccgaataatt tagcctcagc tggataataa
     1381 tttatgcaat caatcctccc tgaattaaaa aacttttcac gtaatatgta cgattgttca
     1441 tctgcgaaaa aagatgcagg cataactata gctaccaatc catttttatt acatatttct
     1501 aagctaagtt ctgcaccaac acgtgaaaga ttagtccccc acccagcaaa tttacgcttc
     1561 ggctgagaat atggcaatac tcttgacaaa taatcatcaa actcacgaag agagtctata
     1621 tacatcgatt tcatagatgg ttcaaaaaaa tcgagctctc tagaatctgg ttttatattc
     1681 tcccaaggcg gattggttat aacacaatca aaataatcaa catatttttt aaattcataa
     1741 aaaacatcac tattttttat agtaatgtta atatttgcac ctgctaactt aagttcagac
     1801 aacgcatttt tagcataagt gaggcctgta ttttctatat cgaacagata aacattccac
     1861 tctacatctg gaaaaccatt tatcatccat tgtttaataa gcaatgtaat aagtcgacca
     1921 tcccctgaaa atggatctgc gacattataa ctttttttat cacaggaatt tatcaatggt
     1981 aataacttct ctatcatcaa aagagctatt tttggatctg tatagtattt acctgtcgct
     2041 tttttagtga attttgttgt ctcgtccaag gacagtgaat taattaaatg gatatgtttc
     2101 atgtaaaata tctcttccat taataatatg gattatatca tttaacttgt gaacactcaa
     2161 caataactgt acataaaaac agtcattaaa gatttcccct agagtgagca tcgctataaa
     2221 aatttaaatt aattttatcc tgctccgaaa gaaacagtta tcatttattc cataaagaat
     2281 aacttgcttt ataatcactt taaatatcga tatcaatttt aatactatgg ttacttacca
     2341 tatcaataaa tagcttaacc cgttatctcg atacccctta agaacccctt ccgcaactgc
     2401 aacataatct acgctcatcc acatgcctgg tgcgtattac cgtgaaggag atcggtgagt
     2461 tattgagtga tctcctttca tgaaaatacg cacctggctt taactgttcc tgatataagt
     2521 tgacagtttt ctgtccgtaa aacggttgat gaacttcatc gggcgttttg tatttcaatg
     2581 ccaaatgtga ccgctcatgg ttataaattg ccacgaattc ttttaccatt taccggccct
     2641 acgtcagctc tgcaggacgc gagagtaaaa actcattttc aggattccgt ttatccactc
     2701 agcctgcgca ttctggtggc agttataacc attagtcatt gaacaggtta ttgataaata
     2761 attaaaaaac tcagttttct ggctcgcctg ctcaagctgt tcttcaagtt ccctgattct
     2821 ttgctcgggt gtcagcggga cagtcgccag agccacaggc agtctcctct ttacctggtc
     2881 aggaagtccg gggctccagt caagccggcc atatttacgc aaccagacaa gaacggtgga
     2941 gcgcccctga atgccataac tgcagccggc ctgtttataa gtcatctcgc ctttttcaac
     3001 cttctcaaca acggctattt taaaggatag aggataatca cgttgagtgc gtttgaaccc
     3061 agacatcatc acgttctccg ggtttaagtc aggaacgtgt catagctatt caggacgggt
     3121 caccgacaca aaaaaagtcg cccttgagcg actcgatttg catacggtat ggtg
//
LOCUS       DAFGPF010000233         3160 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFGPF010000233 DAFGPF010000000
VERSION     DAFGPF010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3160
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.235"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..287
                     /locus_tag="LSX49_005098"
     CDS             <1..287
                     /locus_tag="LSX49_005098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL7171351.1"
                     /translation="NYIKEAKYDMAVGHLLLKSFWANEAVFQMMMLSYNLFLLFKFDS
                     LDSSEYRQQIKTFRLKYVFLAAKIIKTARYVIMKLSENYPYKGVYEKCLV"
     gene            543..1418
                     /locus_tag="LSX49_005099"
     CDS             543..1418
                     /locus_tag="LSX49_005099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-15"
                     /protein_id="HBL7171352.1"
                     /translation="MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQS
                     GGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKK
                     SDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGD
                     ETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNT
                     TGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESR
                     RDVLASAAKIVTDGL"
     gene            complement(1465..1797)
                     /locus_tag="LSX49_005100"
     CDS             complement(1465..1797)
                     /locus_tag="LSX49_005100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="HBL7171353.1"
                     /translation="MRPHRHPHTFELLLPLRGRFVVLNFDDRGTVTHRAILGETCTVL
                     EMAAGTWHAVLSLDTGGIIFEVKHGGYQPVAADDYAHWAPAEGEPGTTELMAWYAQAQ
                     VGDSTFAV"
     gene            1811..3160
                     /locus_tag="LSX49_005101"
                     /pseudo
     CDS             1811..3160
                     /locus_tag="LSX49_005101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
BASE COUNT          816 a          760 c          834 g          750 t
ORIGIN      
        1 aaaactatat caaagaagcc aaatacgaca tggcggtggg tcatctcttg ctaaagtcat
       61 tttgggcgaa tgaagccgtg tttcaaatga tgatgctttc atataaccta tttttgttgt
      121 tcaagtttga ttccttggac tcttcagaat acagacagca aataaagacc tttcgtttga
      181 agtatgtatt tcttgcagca aaaataatca aaaccgcaag atatgtaatc atgaagttgt
      241 cggaaaacta tccgtacaag ggagtgtatg aaaaatgtct ggtataataa gaatatcatc
      301 aataaaattg agtgttgctc tgtggataac ttgcagagtt tattaagtat cattgcagca
      361 aagatgaaat caatgattta tcaaaaatga ttgaaaggtg gttgtaaata atgttacaat
      421 gtgtgagaag cagtctaaat tcttcgtgaa atagtgattt ttgaagctaa taaaaaacac
      481 acgtggaatt tagggactat tcatgttgtt gttatttcgt atcttccaga ataaggaatc
      541 ccatggttaa aaaatcactg cgccagttca cgctgatggc gacggcaacc gtcacgctgt
      601 tgttaggaag tgtgccgctg tatgcgcaaa cggcggacgt acagcaaaaa cttgccgaat
      661 tagagcggca gtcgggaggc agactgggtg tggcattgat taacacagca gataattcgc
      721 aaatacttta tcgtgctgat gagcgctttg cgatgtgcag caccagtaaa gtgatggccg
      781 cggccgcggt gctgaagaaa agtgaaagcg aaccgaatct gttaaatcag cgagttgaga
      841 tcaaaaaatc tgaccttgtt aactataatc cgattgcgga aaagcacgtc aatgggacga
      901 tgtcactggc tgagcttagc gcggccgcgc tacagtacag cgataacgtg gcgatgaata
      961 agctgattgc tcacgttggc ggcccggcta gcgtcaccgc gttcgcccga cagctgggag
     1021 acgaaacgtt ccgtctcgac cgtaccgagc cgacgttaaa caccgccatt ccgggcgatc
     1081 cgcgtgatac cacttcacct cgggcaatgg cgcaaactct gcggaatctg acgctgggta
     1141 aagcattggg cgacagccaa cgggcgcagc tggtgacatg gatgaaaggc aataccaccg
     1201 gtgcagcgag cattcaggct ggactgcctg cttcctgggt tgtgggggat aaaaccggca
     1261 gcggtggcta tggcaccacc aacgatatcg cggtgatctg gccaaaagat cgtgcgccgc
     1321 tgattctggt cacttacttc acccagcctc aacctaaggc agaaagccgt cgcgatgtat
     1381 tagcgtcggc ggctaaaatc gtcaccgacg gtttgtaata gcggaaacgg aatggggaaa
     1441 ctcattccgt ttttgtttat cgccttagac ggcaaaagtg ctgtcgccca cctgcgcttg
     1501 cgcataccag gccataagct ccgtggttcc tggttctcct tccgctggag cccagtgcgc
     1561 atagtcatcg gcagccacgg gttgatagcc accgtgtttt acttcaaaaa ttatgccacc
     1621 ggtatccagc gacagcacgg catgccaggt tcctgcggcc atctccagca ccgtacaggt
     1681 ttcccccaat atcgcccgat gggtgacggt accccgatcg tcaaaattca gcaccacgaa
     1741 acgacccctt aatggcaaca gtagctcgaa ggtgtgaggg tgtcggtgcg ggcgcacgta
     1801 ggtcccaggt catattcctt ccggcgtccg gcattttacc gccagacagc tcgggattcg
     1861 tgatatcacc gttcttgcag aatacggtca gagggaaaat acccgccgtg agcatgcagc
     1921 gctgatacgt cagcactatc agtatcgtga atttgcctgg ccctggacat ttcgccttac
     1981 ccgtctttta tatacccgga gctggataag caacgaacgt cctggcctgc ttttcgatct
     2041 ggcgacaggg tggcttatgc aacatcgtat tattctcccc ggagccacta cgctgacccg
     2101 gttgatttca gaggtaaggg aaaaggcgac gttgcgcctg tggaacaaac tggcactgat
     2161 accgtcagcc gaacagcgtt cacagctgga gatgctgctg gggccaactg attgcagccg
     2221 cctgtcttta ctggaatcac tgaaaaaggg ccctgtgacc atcagtggtc cggcgtttaa
     2281 tgaagcaatt gaacgctgga aaactctgaa cgattttggc ctgcatgctg aaaacctgag
     2341 tacactcccg gctgtgcgcc tgaaaaatct cgcacgttat gctggtatga cttcggtgtt
     2401 caatattgcc aggatgtcac cgcagaaaag gatggcggtt ctggttgcct ttgtccttgc
     2461 atgggaaacg ctggcgctgg atgatgcatt ggacgttctg gacgccatgc tggccgttat
     2521 catccgtgac gccagaaaga ttgggcagaa aaaacggctc cgctcgctga aggatctgga
     2581 taaatctgca ttggcgctcg ccagcgcatg ttcgtacctg ctgaaagaag aaacaccgga
     2641 cgaatcgatt cgtgctgagg tgttcagcta catcccaagg caaaagctgg ctgaaatcat
     2701 cacgcttgtc cgtgaaattg cccggccctc agacgataat tttcatgaag aaatggtgga
     2761 gcagtacggg cgcgttcgtc gtttcctgcc ccatctgctg aataccgtta aattttcatc
     2821 cgcacctgcc ggggttacca ctctgaatgc ctgtgactac ctcagccggg agttcagctc
     2881 acggcggcag ttttttgacg acgcaccaac ggaaattatc agtcggtcat ggaaacggct
     2941 ggtgattaac aaggaaaaac atatcacccg caggggatac acgctctgct ttctcagtaa
     3001 actgcaggat agtctgaggc ggagggatgt ctacgttacc ggcagtaacc ggtggggaga
     3061 tcctcgtgca agattactac agggtgctga ctggcaggca aaccggatta aggtttatcg
     3121 ttctttgggg cacccgacag acccgcagga agcaataaaa
//
LOCUS       DAFGPF010000234         2963 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.236, whole genome shotgun sequence.
ACCESSION   DAFGPF010000234 DAFGPF010000000
VERSION     DAFGPF010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2963
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.236"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1194
                     /locus_tag="LSX49_005102"
     CDS             <1..1194
                     /locus_tag="LSX49_005102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL7171354.1"
                     /translation="GMFLLVHPNGSRYWRLRYRILGKEKTLALGVYPEVSLSEARTKR
                     DEARKLISEGVDPCEQKRAKKVVPDLQLSFEHIARRWHASNKQWAQSHSDKVLKSLET
                     HVFPFIGNRDITTLSTPDLLIPVRAAEVKQIYEIASRLQQRISAVMRYAVQSGIIRYN
                     PALDMAGALTTVKRQHRPALDLSRLPELLSRIDGYKGQPVTRLAVMLNLLVFIRSSEL
                     RYARWSEIDIDNAMWTIPAEREPLPGVKFSYRGSKMRTPHLVPLSQQAVAILAELQTW
                     AGENGLIFTGAHDPRKPISENTVNKALRVMGYDTTKEVCGHGFRAMACSALIESGLWS
                     RDAVERQMSHQERNGVRAAYIHKAEHLEERRLMLQWWADFLDANREECISPFEYAKVN
                     NPLKR"
     gene            1450..2493
                     /locus_tag="LSX49_005103"
     CDS             1450..2493
                     /locus_tag="LSX49_005103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL7171355.1"
                     /translation="MTGKLRFEVNDNQGCFIFPETWFGSLLDEFEELIDAYDADEISE
                     TSYINKLRRLARQENDFIDVHAHLAYVFLEQNAPRKALNAALKGLAIGNRLIPEGFSG
                     RIIWIHPDNRPFLRALYAAILANAHLQRHQDAIMLIEKILDYNPEDNHGARWLLGPEL
                     LRTGAHEQARHILQEHADEFSPYWYELGLLHFLNGELVKAATAFRRGFAANTYIAEIL
                     CGNLHPFPLAVWHNFSGGPDTAEDYYATYHPLWGQYPEALLFVNWLYNHSSVLHERAE
                     IIKCAEMLMQEDDFEICESILRQQEKLRERIDETLSEKIVQKCRNMNGEYIWPWILPF
                     SAAGMKHTGIQYQ"
BASE COUNT          816 a          682 c          673 g          792 t
ORIGIN      
        1 ggcatgttcc tgctggtaca tcctaatggt tcccgttact ggcgtctccg ttatcgtatt
       61 ctgggtaagg agaaaaccct ggcacttggt gtgtatccgg aagtttctct ctccgaagct
      121 cgtacaaaac gggatgaggc ccgaaaactg atttcggagg gggttgaccc ttgcgaacag
      181 aaaagagcta aaaaagtagt ccctgattta cagctctctt ttgaacatat tgcacgacgc
      241 tggcatgcca gtaataaaca atgggcacaa tcacacagcg ataaagtact caaaagcctc
      301 gagactcacg ttttcccctt tatcggcaac cgggatatca caacactcag taccccggat
      361 ctgcttatcc ctgttcgtgc tgcagaagtt aaacaaattt atgaaatcgc cagtcgtctg
      421 cagcaaagaa tatctgctgt aatgcgttat gccgtacagt ctggcatcat cagatataac
      481 ccggctctgg atatggctgg tgcattgacc acggtaaaac gccagcatcg ccctgctctg
      541 gatctttcac gcctgcctga acttctgtcg cgtattgacg gttataaagg ccagcctgtc
      601 acccgactgg cagttatgct gaatttactg gtttttattc gttccagtga actcagatat
      661 gcccgctggt ctgaaattga tattgacaat gccatgtgga ctattccagc cgaacgcgaa
      721 cctctgccag gcgtaaaatt ttcataccgg ggctccaaga tgcgaacacc acatcttgtg
      781 ccactcagcc aacaggctgt agccatactg gcagaacttc agacatgggc aggtgaaaat
      841 ggtctgatct ttacgggagc acacgaccca cgtaaaccaa tcagtgaaaa taccgtaaat
      901 aaggccctca gagtgatggg gtatgacaca accaaggaag tctgtggcca tggattccgg
      961 gcgatggcgt gcagtgcatt gattgaatcc ggcttatggt caagagatgc ggttgaacgt
     1021 cagatgagtc atcaggagcg caacggagta cgtgccgcgt atattcataa agcagaacat
     1081 ctggaagaac gtcggcttat gctgcaatgg tgggcagatt ttctggatgc aaacagggag
     1141 gagtgtatca gtccgtttga atatgcaaaa gttaacaatc cactgaaaag gtgactgaac
     1201 gccatttaca cacatgctct tcctcttaag gggaagagca cccgcctcaa tcaatttctt
     1261 ttttatgccg gcggaaccat cagccaggct gaggttctca ttcaataact caacgtctta
     1321 ccacagaaca gaattcactg tattatcatg ggcaacgtta atcccggaca ataaaaggac
     1381 accgatgcca ggcatcacaa tttttatagc ctgcaggtta tggtccatcc ttttttacag
     1441 gttcagaata tgactggcaa attacgcttt gaagtgaacg ataaccaggg ctgtttcata
     1501 tttccggaaa cctggtttgg ctcgttgctg gatgagtttg aagaactgat tgatgcatac
     1561 gatgcggatg aaatcagcga aacaagttac atcaacaaac tcaggcgcct tgcccgacag
     1621 gagaatgact ttattgatgt acacgctcac ttggcatacg tatttctgga gcagaatgcc
     1681 ccgcgtaagg cgctgaatgc tgcccttaaa gggctggcaa ttggcaatcg tcttatccct
     1741 gaaggtttca gtggcagaat catctggata catcctgaca accgaccttt tcttcgtgcc
     1801 ctctatgcgg caatcctggc aaatgcacat ttacagcgtc atcaggatgc catcatgctc
     1861 attgaaaaaa tactggatta caatcccgaa gataatcatg gtgcacgctg gctactggga
     1921 ccggaactgt tacgcactgg cgctcatgaa caggcacgcc atatactgca ggaacatgca
     1981 gatgaatttt caccttactg gtatgaactc ggccttctgc attttcttaa tggggaactg
     2041 gtaaaagctg caactgcatt tcgtcgcggc tttgcggcaa atacttacat cgcagaaata
     2101 ctgtgcggaa atctgcatcc atttccactt gctgtatggc ataacttttc aggcggtccg
     2161 gatactgccg aagattatta tgccacatac cacccgttat gggggcaata tccggaagca
     2221 ttgctgtttg taaactggct ctataatcat tcctctgtgc tgcatgaacg ggcagaaatc
     2281 attaaatgcg ccgaaatgct gatgcaggaa gatgatttcg aaatatgcga aagtatttta
     2341 agacagcagg agaagttgcg tgaaagaatt gatgagacgc tttctgagaa aattgtacag
     2401 aaatgcagaa atatgaatgg tgaatatatc tggccctgga tattgccgtt ttcagcggca
     2461 ggcatgaaac atactggcat acagtatcag tagatattgc attagtgtat cctgcacaca
     2521 agtaataatt tattcaccaa taataacact gttaatgccc ccttcccctg gttgtcagcc
     2581 aggggttatc ttctgaatat ttcttttgaa aaggataaca cagtaaatta tttttatgaa
     2641 ttatcccatg gactcattaa caccctttca tgatgcttta ttgtcaaaca cgttatggct
     2701 gacatcaaaa aaaaccggat ttcctctgcc agcgggtaat caccttcccg gtgttttcgg
     2761 ttggtctggt tactcctgtc tggttattag caagataatt gctataaaca gtggaaaact
     2821 catcgtacat aatctggtga tgaacattac gcttattttc ccttgaccgg aagaatcaga
     2881 ggctgtggtt tcagactgtc tgccagtaca ttcctctctc cgttaaaaac cataacgggt
     2941 tcattatctt cgtctgtcag cag
//
LOCUS       DAFGPF010000235         2961 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFGPF010000235 DAFGPF010000000
VERSION     DAFGPF010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2961
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.237"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..98)
                     /locus_tag="LSX49_005104"
     CDS             complement(<1..98)
                     /locus_tag="LSX49_005104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL7171356.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNT"
     gene            187..297
                     /locus_tag="LSX49_005105"
                     /pseudo
     CDS             187..297
                     /locus_tag="LSX49_005105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            341..496
                     /locus_tag="LSX49_005106"
                     /pseudo
     CDS             341..496
                     /locus_tag="LSX49_005106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            1623..2768
                     /locus_tag="LSX49_005107"
     CDS             1623..2768
                     /locus_tag="LSX49_005107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001388349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171357.1"
                     /translation="MGKELDDICTSCPYIDAVKRHKQQLGAIEEYTKWLKKEPRASYF
                     FLFRLYTRIHNTFFPQKQQLPFTPGGTHCPEPDVTLRDLTLSPGYHSDYAPHPIPEMD
                     SSIVVPPTNENTSPPEDTPDNTPAGGNTGQAEKTRNAGLTPIPEKRSGMPPEHLRFAM
                     GFPSQPKIAGPREKPMRTVHPDNIYREIIWFCSSYLLKSGPEATRTIINSVFSEWASI
                     NNDYPSPFSWVDSRDSEQCDWLWNAMQVRCVGTPLNPLTPEQKYWFACATFDNWEGWN
                     EQQVQFLLESNPRRNRAKFTQASFQAPRIQHKAILLDELKSAREQQKRRDERADGSVP
                     LKLSGKIHKQLESIARSRGVLPKKLLNEMIEQAYQDFVANEQHKTLS"
BASE COUNT          854 a          715 c          714 g          678 t
ORIGIN      
        1 gtattgcggg agatccccag ttctctggca atcgcccggc tactcattcc ctgcttgtgc
       61 aggattttaa tttccataac tgtctcaaaa gtgaccataa gctctcctga atcaggagag
      121 cagattaccc cctggatctg atttcaggcg ttgggtgtgg atcactattg caccgttcgt
      181 gacacaatgg gccatacggg ccgacgttcc atgccgcgtt actacattca gcccggacgt
      241 aaaatgcgcc cgtcaaaaag aacggttcgc ttcgaaactc agccaggata ccacctctcc
      301 gccacacccg ggaagaagtt gatatggtgg ttgccggaca acagagctct tggattgact
      361 gctgcatcac tcaaccacgc tgaatatcaa aggagagcgt taccggttaa aagagaaacg
      421 taaagctgtg gtgatgaccc aaaacgcaac gcctgtcagt gaggatgaaa tggtgaaaag
      481 cggacagcat cagtaacgga agtatcttag cgggtacgaa aatggcagga tcgtgacatt
      541 gacagaatat ctcctgatca tcctgaatga ctgcagttgc tgtggaaaag taagctgtct
      601 ccacccacgg cacgacttaa caggcattcc gtaactcccc cagacttact atgacgcatt
      661 atcggtgcac ttaaaaccgc agaccgcatt gcgggtgtta ctgcatgaca gtctgaccgt
      721 attgtgagat gtcggcagga accgatgtcc gcgcaggggg gaacttcctg cagtacctga
      781 cgcttcaaat agtattaacc gtagggcgtt gttggttccg gatcgcggaa atgggagcac
      841 aggtctgcta cggggtgtac ctctgacagt aaatccggct cgctcatctg acagcctctc
      901 tcccggaaaa gaccaaaaat gagatcgtct cctcaacagc agagaagagg tcttgacaga
      961 caggctacat tgcatacgat ttatgaagaa aaagacagca aatatggagg ttatagcgga
     1021 gaacacccta cgaaattcct atgaaaaacg attgaaaaaa atatcaaatt cgattcgttt
     1081 ttatatgctt tttgggaacg tggcgatgac gaactgttgc atgtgcagag gagaatgcac
     1141 ccggaagcac cagaatcatc cagaaaggca gaacgattac gcatcaaacc aggagacagc
     1201 aatatcaagg taatacactg atttaaaatg aatttacagc aatacgtgaa aacatttttt
     1261 acttaaagga gacagatgcg ctgaagagag tgcaggtatt tttatataaa aatgagaaga
     1321 ttacgggata tatatccggc acactatgac cggagaatac cagtcaggct taaaaagaca
     1381 ataaatacag tgagttaaat acacagagaa aacgaaaacg tagtatcaga gggtacatct
     1441 tacaacagag actgaatttc cggtttttca taaccggcgc attccggaaa atgcaggcgg
     1501 cccggagctc ttctgacgcc agtacctgat agattgttct gtacattctg tacatcatgt
     1561 acggaggttt ttgtttgctt tcttaaaatc tgcaaatgtg ggaagagcag gtgaggtgta
     1621 ttgtgggaaa ggaactggat gatatctgca ccagctgtcc gtatatcgat gctgtaaaac
     1681 ggcacaaaca acagctcggt gccatagagg aatatacaaa gtggttaaaa aaagaaccac
     1741 gggcatctta tttttttctg ttccggctgt atacccgcat tcacaataca tttttccccc
     1801 aaaagcaaca actcccgttc actcccggtg gcactcactg cccggaacct gatgtcaccc
     1861 ttcgggactt aacgctttcc ccgggctacc acagtgatta tgcccctcac cccattccgg
     1921 agatggacag ttctattgtt gttcccccca ctaatgaaaa cacctcgcct ccggaagata
     1981 ctcccgacaa cactccggcc ggaggcaata ccggacaagc ggaaaagacc agaaacgcag
     2041 gactcacacc cattcctgaa aaacgttcag gaatgccccc ggaacatctg cggtttgcca
     2101 tgggttttcc atcgcaaccg aagattgccg gtcccagaga aaagccgatg cgcaccgtgc
     2161 atccggataa tatctaccgt gaaattatat ggttctgctc cagttacctg ctgaaatccg
     2221 gaccagaggc tacgaggacg attatcaact cagtattctc tgaatgggcc agcataaaca
     2281 atgattaccc ctcccccttt tcgtgggtgg acagcaggga cagtgaacag tgtgactggt
     2341 tatggaacgc catgcaggtc cggtgtgtgg gaaccccgct gaatcccctt accccggagc
     2401 agaaatactg gttcgcctgc gccacgtttg ataactggga aggctggaat gagcaacagg
     2461 tacagttttt actggaaagt aatcccagac ggaacagagc gaagtttacg caggcctcct
     2521 tccaggcccc caggattcag cataaagcga ttcttcttga tgagctgaaa agtgcccggg
     2581 agcaacaaaa aaggcgtgat gaacgtgctg atggttccgt cccgctgaaa ctgtccggaa
     2641 aaatccacaa acagcttgaa agtattgccc gaagtcgtgg tgtcctccca aaaaaactgc
     2701 tgaatgaaat gattgagcag gcgtaccagg actttgtggc aaatgagcaa cacaagacac
     2761 tgagttaagg accgcagggc ctccggttac cgattctgca gcatacacaa cgaatgtgtc
     2821 cggctcttac ctgtgggggc cgcactaaag ttacgcattg agtatgagtg ggtaatcccg
     2881 gatgagaata tcccagtttt tacactattc actgaaggtg cgacatatca ttcagtctct
     2941 ctgaattctt catttcagtg g
//
LOCUS       DAFGPF010000236         2807 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.239, whole genome shotgun sequence.
ACCESSION   DAFGPF010000236 DAFGPF010000000
VERSION     DAFGPF010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2807
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.239"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            95..820
                     /locus_tag="LSX49_005108"
     CDS             95..820
                     /locus_tag="LSX49_005108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL7171358.1"
                     /translation="MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDL
                     TLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLM
                     CPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
                     VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELN
                     LPSVYGDAAEWNTAELRREMSHS"
     gene            778..1455
                     /gene="bglJ"
                     /locus_tag="LSX49_005109"
     CDS             778..1455
                     /gene="bglJ"
                     /locus_tag="LSX49_005109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HBL7171359.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQ
                     ESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEA
                     SNVLHPY"
     gene            complement(1493..2281)
                     /gene="fhuF"
                     /locus_tag="LSX49_005110"
     CDS             complement(1493..2281)
                     /gene="fhuF"
                     /locus_tag="LSX49_005110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HBL7171360.1"
                     /translation="MAYRSAPLYEDVIWRTHLQPQDAGLAQAVRATIAKHREHLLEFI
                     RLDEPAPLNAMTLAQWSSPNALSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVSPEHFHAEFHETGRAACFWVDVCDDKNATPHSPQQRMETL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHAIFFEK
                     TLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            2422..2658
                     /locus_tag="LSX49_005111"
     CDS             2422..2658
                     /locus_tag="LSX49_005111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HBL7171361.1"
                     /translation="MLQRTLGSGWGVLLPGLLITGLMYADLSPDQWRIVILMGLVLTP
                     VMLYHKQLRHYVLLPSCLALIAGIMLMIMNLNQG"
     gene            complement(2697..2783)
                     /locus_tag="LSX49_005112"
     tRNA            complement(2697..2783)
                     /locus_tag="LSX49_005112"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2747..2749),aa:Leu,seq:cag)
BASE COUNT          737 a          614 c          706 g          750 t
ORIGIN      
        1 tattcgctta atctattaat ttgctggaaa catttaagga atgaatatcc tgaataaacc
       61 atcataattt ttagacagtg gatgtggagg aaatatgttg ccaggatgct gcaaaaatgg
      121 aattgttatc agtaaaatac ctgttatgca agcagggtta aaagaggtca tgaggactca
      181 cttccctgaa tatgaaataa tatccagcgc ctctgcggag gaccttacct tattacaatt
      241 acgtcgttcc ggattagtca ttgctgattt agccggtgaa agtgaagatc cacgttctgt
      301 ttgtgaacat tattattctt taatctcaca atatcgggaa attcactggg ttttcatggt
      361 gtcacgctcc tggtattccc aggcagtaga actgctcatg tgccctacgg cgacgttatt
      421 gtctgatgtt gaacccattg agaatctggt caagaccgta cgttccggca atacgcacgc
      481 agagcgtatc agcgccatgc tgacctctcc ggcaatgact gaaactcatg attttagcta
      541 tcgctccgtc attctcactc tttcagagcg caaggtactg cggctattag gtaaaggatg
      601 gggcatcaac cagatagctt cattgcttaa gaaaagtaat aaaactatca gcgcccaaaa
      661 aaacagtgcg atgcgtcgac tggcaattca cagcaacgct gaaatgtatg catggataaa
      721 tagcgcgcag ggtgcaagag aacttaactt gccttctgtt tatggagatg ccgcagaatg
      781 gaacacagcc gaattaagaa gagaaatgtc gcactcatag aaaaatgcgt catgagtagt
      841 atcggtattg agagtttatt cagaaagttt gcgggcaacc cttataagct ccatacctat
      901 accagtcagg agtcatttca ggatgccatg tcgcggatct cgtttgcggc ggtcattttt
      961 tctttttctg ccatgagaag tgagcgcaga gagggattat cttgcctgac tgaactggcg
     1021 attaagtttc cgcgtacccg gcgtttagtt attgcggatg atgatattga agctcggctg
     1081 attggttcat tgtcgccatc accgctggac ggtgtattaa gtaaagcgtc aacgctggag
     1141 atttttcatc aggaactctt tttgtcatta aatggtgtac gtcaggcgac cgaccgactg
     1201 aacaatcagt ggtacattaa ccaaagccgg acgctaagcc cgacggagag agaaatattg
     1261 cgctttatgt cgcgtggcta ctcaatgaca caaattgccg agcagcttaa acgcaatatc
     1321 aaaacgatcc gcgcgcataa atttaatgtg atgtcgaaac tgggcgtcag ttctgatgca
     1381 ggattgttgg aggccgcaga tattctgtta tgtatgcggc attgcgaagc aagtaatgtg
     1441 ttgcatccct attaatccgc atgatgccgg gtttacttcc ccggcagtgc tttcatttca
     1501 gcgtacaatc gccacattgc tgcacatccg gtaagcgata acgctggcag caagtgcggc
     1561 gcaccagcag gccgtcgcgc agtaccacgg tacgccagag tggattatct tcaccgttcg
     1621 tgagcgtttt ctcaaaaaag atggcatggc gcagcgattc aaccgtcgcc tcgccgagca
     1681 gttgcttcat ctcagtgaga taccagttga tcaaataacc ggtattactc cagataagtt
     1741 tgccgttgat ctctccggtc gcttctagtg cctgcacaac cggaaccagc gcctggctga
     1801 ttaacgtttc cattcgctgc tgcggcgaat gtggtgttgc gtttttatcg tcacacacat
     1861 cgacccagaa acaggcggca cggccggttt cgtgaaactc agcatggaaa tgttccggcg
     1921 acacatctaa tgctttttcc tgcgtcagta gcgccagcat taatggtggc accatcaggc
     1981 cgatatacca ttgtgcccat agtgagatca gcggtttgtt ctcgcggatc atcgttggtt
     2041 ggttgcgata gatatgatcg gaatagaccg cgagtagaga acttagcgca ttcggtgatg
     2101 accattgcgc cagcgtcatg gcgttaagcg gagcgggttc atccaggcgg ataaactcga
     2161 gcaaatgttc acgatgtttg gcgatcgtcg cacgtacggc ttgtgcaagc ccagcatcct
     2221 gtggctggag atgcgttcgc cagataacat cttcatagag cggtgcggaa cgataggcca
     2281 taatcgggat agtaatctaa atgataatga ttgctaatcc tagcgatagg tttatccgat
     2341 agcaagggat ttctctggct tgcaaatgat aaaaattatc atatgatatt ggttatcatt
     2401 atcaatgaaa gagatgaaac catgttgcaa cgtacgctgg gcagtggctg gggagtgttg
     2461 ctgccgggat tgctgattac agggctgatg tatgcggatt tatcgccgga tcaatggcgg
     2521 attgtcattc tgatgggatt ggtattgacg ccggtgatgc tgtatcacaa acagttacgg
     2581 cattacgttt tgctaccatc gtgcctggcg cttattgctg gcatcatgct gatgataatg
     2641 aatttgaatc aggggtgata aaacagtgaa gagacaagaa aagaagtaaa gataattggt
     2701 gcgagggggg ggacttgaac ccccacgtcc gtaaggacac taacacctga agctagcgcg
     2761 tctaccaatt ccgccacctt cgcacagtca tcttactttt tttgata
//
LOCUS       DAFGPF010000237         2747 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFGPF010000237 DAFGPF010000000
VERSION     DAFGPF010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2747
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.241"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            64..2343
                     /gene="ydeP"
                     /locus_tag="LSX49_005113"
     CDS             64..2343
                     /gene="ydeP"
                     /locus_tag="LSX49_005113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HBL7171362.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDDVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPHAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKSGAQAVTVEDSMSMVHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
     gene            2591..>2747
                     /gene="safA"
                     /locus_tag="LSX49_005114"
     CDS             2591..>2747
                     /gene="safA"
                     /locus_tag="LSX49_005114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HBL7171363.1"
                     /translation="MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLG
                     ISEMGRMA"
BASE COUNT          737 a          641 c          674 g          695 t
ORIGIN      
        1 gtatatattg tgcatcatcg ctattacaaa tcctaataat tcatttccac acaggataag
       61 cagatgaaga aaaaaattga atcctaccag ggagctgccg gtggttgggg tgctgttaaa
      121 tccgtagcga atgcagtacg taagcagatg gatatacgcc aggatgttat tgccatgttt
      181 gacatgaata agccagaggg ctttgactgt ccgggatgtg catggccaga tcctaagcac
      241 agtgcgtcat tcgacatttg tgaaaacggc gcaaaagcaa tcgcctggga agtcacggat
      301 aagcaggtaa atgcctcttt ctttgctgag aatacggttc aatcattact tacctgggga
      361 gatcacgagc ttgaggctgc gggacgtctc actcagcctt tgaaatatga tgacgtcagc
      421 gactgttaca agccattaag ctggcaacaa gctttcgacg aaattggcgc tcgccttcaa
      481 agctatagtg atcccaatca ggttgaattc tatacttcgg ggcgcacttc caatgaagct
      541 gcctttcttt atcagctttt tgcccgtgaa tacgggagca ataactttcc cgactgctcc
      601 aacatgtgcc atgaaccgac cagtgtggga ttggcagcga gtatcggtgt gggtaaaggg
      661 accgtgttgc tggaagactt tgagaaatgc gatttagtca tttgcattgg gcataaccct
      721 ggtacaaacc accctcgcat gctgacttcg ttgcgcgctt tagtgaaacg gggagcgaaa
      781 atgatcgcta tcaaccctct acaggaacgt ggcctggagc gatttaccgc accgcaaaac
      841 ccgtttgaaa tgctgacgaa ctctgagact cagttagcca gtgcctacta taacgtgcgc
      901 attggtggcg atatggcgtt gctcaagggg atgatgcgcc tgttaattga gcgcgatgat
      961 gctgcaagcg ccgcaggtcg gccctcattg ctggatgacg aatttattca aacgcatacc
     1021 gtcggctttg acgagctacg ccgtgacgtg ctcaattccg agtggaaaga tatcgaacgt
     1081 atttctggac taagtcagac acaaatcgcc gaacttgctg atgcatatgc cgctgccgaa
     1141 cgaaccatta tctgttacgg aatggggatc actcagcacg aacatggtac ccagaacgta
     1201 cagcaactgg tcaatctgct gttgatgaaa ggtaacattg gcaagcctgg tgcgggtatc
     1261 tgcccactac gaggtcactc taatgtacag ggcgaccgaa ccgtcggtat caccgagaaa
     1321 ccgtctgcag agtttctggc tcgcctgggt gagcgctatg gcttcacccc acctcatgca
     1381 cctggacatg ctgcaatagc cagcatgcaa gctatatgta cggggcaagc tcgagcattg
     1441 atctgcatgg ggggcaactt tgcactggca atgccagatc gggaagcgag cgctgtaccg
     1501 ttaacgcaat tagatctggc ggtacacgta gccactaagc ttaaccgctc tcatctgctg
     1561 accgcacggc atagctatat tctgccggtt ctgggacgta gcgagattga catgcaaaaa
     1621 agcggtgcgc aggcggtaac cgttgaggat tcaatgtcga tggttcatgc ctcgcgtggt
     1681 gtgttaaaac ccgccggtgt aatgctgaaa tcagagtgtg cagtggtcgc gggaatcgcg
     1741 caggcagcac taccccagag cgtggtagcc tgggagtatc tggtggaaga ttatgatcgc
     1801 attcgcaatg acattgaagc tgtgctgcca gagtttgccg actataacca gcgcatccgt
     1861 catcctggtg gttttcacct gataaacgca gctgctgaaa ggcgctggat gacgccgtca
     1921 ggtaaggcta atttcattac cagcaaaggg ctgttagaag atccttcttc agcgtttaac
     1981 agtaagctgg tcatggcgac agtacgcagc cacgatcagt acaacacgac gatttatggt
     2041 atggatgatc gctatcgagg tgtattcggt caacgagatg tggtctttat gagtgctaaa
     2101 caagctaaaa tttgccgtgt aaaaaacggc gaaagagtta atcttattgc actcacgcca
     2161 gacggtaaac gtagctcacg ccgcatggat agattaaaag tggtcattta ccctatggct
     2221 gaccgctcac tggtgaccta tttcccagaa tcgaatcaca tgctaacact tgataaccac
     2281 gatccattaa gtggcattcc tggctataaa agtattccgg ttgaattaga accatcaaat
     2341 taattctcct cctcatttct tctgctgtca tccgcacagc agaagaattc ctcattgact
     2401 attatcgcgc aatttgctca catggattaa attaaactac acactataag atataaacct
     2461 ctgcctacag ttgtaagaaa ctccgctcag tactgaagtg ccagtcctat ttcctctttt
     2521 atccagcctg ttatattaat catactgatt aacgattttt aacgttatcc gctaaataaa
     2581 cacatttgaa atgcatgcga ccacagtgaa aaacaaaatc acgcaaagag acaactataa
     2641 agaaatcatg tctgtaattg tggttgtctt gttactgaca cttacgttga tagccatttt
     2701 ttcggcaatt gatcagctgg gcatttcaga aatgggtcgc atggcaa
//
LOCUS       DAFGPF010000238         2635 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.242, whole genome shotgun sequence.
ACCESSION   DAFGPF010000238 DAFGPF010000000
VERSION     DAFGPF010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2635
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.242"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..2258
                     /gene="vgrG"
                     /locus_tag="LSX49_005115"
     CDS             <1..2258
                     /gene="vgrG"
                     /locus_tag="LSX49_005115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HBL7171364.1"
                     /translation="ITSFKHLSSSQDEARYEVRLEPRMALLTRSRQNAIYQNQTVPQI
                     VEKILRERHQMRGQDFVFNLKNEYPAREQVMQYGEDDLTFVSRLLSEVGIWFRFATDA
                     RLKIEVVEFYDDQSGYERGLTLPLRHPSGLFDGETEAVWGLNSAYSVVEKSVSTRDYN
                     YREATAEMTTGQHDATGGDNTTYGEAYHYADNFLQKGDKEAAESGAFYARIRHERYLN
                     EQAILQGQSTSSLLMPGLEIKVQGDDAPAVFRKGVLITGVTASAARDRSYELTFTAIP
                     YSERYGYRPALIPCPVMAGTLPARVTSTVKNDIYAHIDKDGRYRVNLDFDRDTWKPGY
                     ESLWVRQSRPYAGDTYGLHLPLLAGTEVSIAFEEGNPDRPYIAGVKHDSAHTDHVTIQ
                     NYKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQLNLGHLVDAGKQQRGEGFELR
                     TDLWGTVRAKKGIFISSDAQDKAQGKVREMAPAMAILDGAQSQMKSLSTDAQTANADP
                     ADLSSQIALLQQSVKDLTQAAILLSAPKGVAIASGEHLQLAASKNLIANAGNHADIGV
                     VKNMFIGVGQALSVFVRKAGIKLFANKGAISVQAQNDLMELLAQKSIEITSTEDEIKI
                     TAKKKITLNGGGSYIRLDACGIEAGTPGEYNVKAGYYGRKPKAKLTPELMAFPVIKSE
                     DFNQSFILLDENTGQPLINWPYELELESGLKMSGITDENGNTELISSDKEEVVNISVF
                     EPDEFLDDEIN"
     gene            2280..>2635
                     /locus_tag="LSX49_005116"
     CDS             2280..>2635
                     /locus_tag="LSX49_005116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171365.1"
                     /translation="MADKSEKKKETTNKSAKKTLTKKSEKLTPAKDTAPKQVNVDPAI
                     RLKQIRQLVRNNNKSIMGEDYIICQIYKESRFKQFAGKNKHNAKGLMQMQRNAVRQVF
                     KYRQQKIKGRMTTDKET"
BASE COUNT          767 a          645 c          725 g          498 t
ORIGIN      
        1 tcattaccag ctttaaacac ctctcatcgt cacaggacga agcccgttac gaagtgcgcc
       61 ttgaaccccg tatggcgctg cttacccgca gccgccagaa cgccatctac cagaaccaga
      121 cggtgccgca aatcgtcgaa aaaatcctgc gcgagcgcca tcaaatgcgc ggtcaggact
      181 tcgtgtttaa cctcaaaaac gaatacccgg cccgtgaaca ggtgatgcag tacggtgagg
      241 acgacctgac gtttgtctca cgcctgctgt cggaggtggg tatctggttc cgctttgcca
      301 ccgacgcccg gctgaaaatc gaagttgtcg agttttatga cgaccagagc ggctatgagc
      361 gcggactgac gctgccgctt cgtcatcctt cagggctgtt tgatggtgaa acggaagccg
      421 tatgggggtt gaacagcgcg tacagcgtgg tggaaaaaag cgtctccacg cgggactaca
      481 actaccgtga agccacggcg gaaatgacca caggccagca tgacgccacc gggggcgata
      541 acaccaccta cggcgaagcc taccactacg ctgacaactt cctgcaaaaa ggcgataaag
      601 aggcagcgga aagcggcgcg ttttatgccc gtatccgcca cgaacgctat ttgaatgaac
      661 aggccattct acagggccag agcaccagtt cactgctgat gccggggctg gagataaaag
      721 ttcagggtga cgacgcgcca gcggtgttcc gcaagggcgt actgattacc ggcgtgacgg
      781 ccagcgcggc gcgtgaccgc agctatgaac tgacgtttac cgccatcccg tactcagaac
      841 gctatggcta ccgcccggcg cttatcccct gccccgtgat ggccggcacg ctcccggcac
      901 gggtcaccag cacggtgaag aacgacatct acgcccatat cgacaaggac gggcgctacc
      961 gggtcaacct cgactttgac cgcgatacgt ggaaaccggg ttatgaaagc ctgtgggtac
     1021 gccagtcgcg cccgtatgcg ggagacacct acggcctgca tctgccgctg ctggcgggaa
     1081 cggaagtcag catcgcgttt gaggaaggca acccggaccg accttatatt gcaggcgtaa
     1141 aacacgactc ggcacacacc gaccatgtga ccattcagaa ctacaagcgc aacgtactgc
     1201 gcaccccggc gaacaacaaa atccgcctcg atgacgagcg cggcaaagag catatcaagg
     1261 tcagtaccga gtatggcggc aagagccagc tcaacctcgg ccatctggtg gatgccggaa
     1321 aacagcagcg cggggaaggc tttgaactgc gtaccgatct gtggggtaca gtacgggcaa
     1381 agaaaggcat ctttatcagc tccgacgcgc aggacaaggc gcagggtaag gtgcgcgaaa
     1441 tggctccggc gatggcaata ctggatggcg cacagtcaca gatgaagtcg ctgtccactg
     1501 atgcgcagac ggcgaatgcc gatccggcag atctgtcatc acagatagcg ctgttgcagc
     1561 agagtgtaaa agatctgacg caggctgcga tcctgctaag cgcacccaaa ggcgtggcga
     1621 tcgccagcgg agagcacctg caactggcgg cgtcgaaaaa cctgatcgcg aacgcaggaa
     1681 atcacgctga tatcggtgtc gtgaagaata tgtttatcgg cgtgggtcag gcgctgagcg
     1741 tgtttgtacg caaagcgggt atcaaactgt ttgccaataa aggggcgatc tcggtacagg
     1801 cacagaacga tctgatggaa ctgttggcgc agaaatcgat agagatcacc agtacggaag
     1861 atgagattaa aatcaccgcg aagaagaaaa tcacccttaa cggcggtggc agctacatcc
     1921 ggctggatgc ctgtgggata gaggccggta cgccgggaga atataacgtt aaggcgggat
     1981 attacgggcg taagccgaag gcgaagctga cgccggagct gatggcattt ccggtgatta
     2041 agtctgagga ttttaatcag agctttattt tgctggatga aaatactggg caaccactta
     2101 ttaattggcc ctatgaacta gaactggaaa gtgggctaaa aatgagtggg attactgatg
     2161 aaaatggaaa tacagaacta atatcctctg ataaggagga ggtcgttaat attagtgtgt
     2221 ttgaacccga tgagttttta gacgatgaaa ttaattaaga catatagcga gaatataaca
     2281 tggcagataa atccgaaaag aaaaaagaaa ccacaaataa atcagcaaaa aaaacactaa
     2341 cgaagaagag cgaaaaatta actccagcaa aagacaccgc accaaaacaa gtgaatgtag
     2401 atccagctat aagattgaaa caaattcgtc aacttgtccg taataataat aaatccatca
     2461 tgggagagga ttatattatt tgtcaaatct ataaagaatc tagatttaag caatttgcag
     2521 gtaagaataa acataatgcg aaaggcttaa tgcaaatgca acgaaatgca gtgaggcagg
     2581 tttttaaata tcgacaacaa aaaataaaag gaagaatgac tactgataaa gagac
//
LOCUS       DAFGPF010000239         2615 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.243, whole genome shotgun sequence.
ACCESSION   DAFGPF010000239 DAFGPF010000000
VERSION     DAFGPF010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2615
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.243"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(254..2521)
                     /gene="adiA"
                     /locus_tag="LSX49_005117"
     CDS             complement(254..2521)
                     /gene="adiA"
                     /locus_tag="LSX49_005117"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HBL7171366.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKINESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEITPREAYNAIVDNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
BASE COUNT          624 a          627 c          696 g          668 t
ORIGIN      
        1 gaatataaac atgcataaaa ataacgagtt ttactaatat tacaaatttt tatagtaatt
       61 tctcatgtac atattttttt acaggctaag aaaaggataa ataacaggca aaaaaaagcg
      121 cggggtggga ccgcgcaaaa agcatgacat tttttgtttg cagcaatttt tatgaaaacg
      181 ttgccatact taaaaggcct caagccaggc ggcgtaatgt tatttaacaa ttacgccttc
      241 agcggaatag tggttacgct ttcacacaca taacgtggta aataccgtca ataatttctg
      301 tcccttctgt ttcgtgttca aatccaggga aatgatgatc ccaggattgc agcgagcgta
      361 aataacttac ttgcggactg tttttatcgc cgaagttttc accagacagc agcatcggga
      421 ttcctggcgg atacgggata actgagtttg ccgcgatacg tcctggcaga ttttcaatgg
      481 ataccagttc gacattgttg tcgacaatcg cgttgtacgc ttcacgcggg gtgatttccg
      541 ccaccggtag gccggaatag gcttcattca accgtgcgcc agggttgttt tctttcagcc
      601 aggcaaacat ggtgtcaccc agatcgtgaa tccccatgtt cgcgtaagtg tcaggatatt
      661 gttcaacaag ttccggcatc acctgcgcca gcggtgtgtt ggcgtcatag tggcgtttga
      721 aggagcaaag ggtgttaacc agagttcccc atttcccacg ggtcacgccc atagagaaca
      781 ggaacataat ctggaagtca gtggtacggg taggcacaat gccgtggcga ccaagccagg
      841 ctgtgaccag cgccgccgga acaccggttt cttccagttc accatcttca cccattcccg
      901 gagcaaggat gctgacttta atcgggtcga gcatactcca gttatccgga atatctttga
      961 agccgtgcca gctttcgccc ggatgcatga cccagcagtc ctgaacggtg gtcagcagtt
     1021 tggttggtgc gtcagcaaag tcataggttt tgccggtttg tgggtcggtg acgacttctt
     1081 tgttccacgg tttgaagaac cagctaccgt cagcggtgaa ctctttatat agccgcgcca
     1141 tcgcctgacg gaaatcaacc gcttcgtcga tcacttcctg ggtcagtgac aggccgctgt
     1201 tgccgtccat catcgacacc gccacgtcgt tggatgcgca gatggcatac agcggggagg
     1261 tggtggcatg catcatgtag gcctggttga agcgggagaa gttaatcgcc ccacgacctt
     1321 cacgtacatg aatataagag gcctgtgaca gcgcattcag cagtttgtgg gtggagtggg
     1381 tggcgaaaac ggtaggaccg ttgtgatcgc caggttcgcc gcgcatggca tagtgatcgg
     1441 catagatcgg gttgaaacgt gcatagccgt accaggcttc gtcaaagtgc agacgatcgg
     1501 aggttttttc cagcagatcc tgcgcttctt tagcgttata acacacgccg tcataggtac
     1561 agttggtcac cacgcagtaa gacggttttt gcccggcttt gtctttagtc agcgggcttt
     1621 cattgatttt cttctgcaag gtttcaggtt gcatttcctg cggatagatt ggcccgataa
     1681 tgccgtagcg gttgcggctt ggcaccatgt agaccggttt cgcacctgtc agcatcaagc
     1741 cttgttcgat ggatttatgg cagttacggt caacgaccac gacatcgtta tcggtcatgc
     1801 aagcctgcat gatggtgcgg ttagagccgg aagtaccgac gactaccgac caggagcgat
     1861 cggcaccaaa tacgcgtgcg gcatattttt cgctttcgcc aaatgcgcca gtatggtcaa
     1921 gcaaagaacc gagggaagtg cgttcgatgc ccatgtcggt gcggaacaga ttttcaccat
     1981 agtagtcatg gtagaaacgt ccggcgggtg ttttggtaaa accaacgccg ccctggtggc
     2041 ctggcgctgc ccaggaatat tcatggatgt cgctatattt catcagcgcg ctgaacagtg
     2101 gcggcaatag ctgctggcgg tagcgggtca tcgcggcaac ggcgcgtccg gcgataaagt
     2161 cggcggtatc ttccagaatc caggcgaatt catcgacaag ctccagcagg tcgcgatcca
     2221 ttgcggcgag ggctttttcc cgatcgccca acaggaagac cggcacgttt tgttggcgct
     2281 catgaagctt accgatcaat tgtctgacgt tttgatgttc gtccggatgt tccatttgat
     2341 agctgaacat caggcagtca atggcttcgt ttgaagagag aatggcaaaa ccatcatcaa
     2401 aggaggtgga tttaatcacg gtaacatttt gctggcttaa agcatctgcc agacgctcaa
     2461 cggcgttacc gacccaggtg tcttgatgga gaaactcgct ttcaacaatt aatactttca
     2521 tcattgctta cccggttatg aaggaatctt cgttgcgggc aagtatcttc cggccttttc
     2581 gggctgtaaa gcgcgtgaaa aacaaacatt tttga
//
LOCUS       DAFGPF010000240         2610 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.244, whole genome shotgun sequence.
ACCESSION   DAFGPF010000240 DAFGPF010000000
VERSION     DAFGPF010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.244"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            249..365
                     /locus_tag="LSX49_005118"
                     /pseudo
     CDS             249..365
                     /locus_tag="LSX49_005118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707819.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
     gene            367..500
                     /locus_tag="LSX49_005119"
                     /pseudo
     CDS             367..500
                     /locus_tag="LSX49_005119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
     gene            complement(575..2026)
                     /gene="nhaC"
                     /locus_tag="LSX49_005120"
     CDS             complement(575..2026)
                     /gene="nhaC"
                     /locus_tag="LSX49_005120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL7171367.1"
                     /translation="MNNNNTPRSPTLVESLLPILAMILLLGFGYAAFDLPPEPLMVLS
                     TVIAALLVKRLGYGYNAILESISQKIAKTMPALLILISVGLLIGTWMIGGTIPLMIYY
                     GLNLINPSMIYVTALLVTAIVSVCTGTSWGSAGTVGVAFMGVAIGMEANLAATAGAIV
                     AGAYFGDKLSPLSGDTNLAAMAAQIDLYEHIAHLLYTTLPSLILSAFVMTLYGMNSEL
                     GGSTIPEKIQLITEGLKGIYHFNLLLLLPIAIVLYGSITKKPTIPIMLVSALVAMINA
                     SVIQGFALHDIVKSAVDGFNVSMLTDKDVNPLLGNLLNRGGMNSMMSTLLICFCALSF
                     AGTLALSGALEVIVHNLLKLVHSTGTMILATIACGLTMISVTCNGQISILIPIEMLRS
                     AYIERGLHPKNLARTVEDSATIFEPILPWTAAGAYMAGTLGVATLSYLPWAILCWSGI
                     FFATLWGFTGFGIARLSKEKQQQLMMETINESK"
     gene            complement(2019..>2610)
                     /locus_tag="LSX49_005121"
     CDS             complement(2019..>2610)
                     /locus_tag="LSX49_005121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL7171368.1"
                     /translation="VHADFNFTQKQHQTISSISSYVAQNSFICTSPAKTFNMAGLEIA
                     NIVIANDKYREQFKLALIAAGIHNPGYFSVPAFLCAYRHGDSWLAALKDYLVENRSWV
                     QSFCQAHFPDWFVASGGGTYMLWIDYRAMNISEEQLRHWFVSLAGVEMSWGSDFGDEG
                     LGFFRVNIATPRSNLTQAFERIYQSIPFTTGVSLHE"
BASE COUNT          776 a          578 c          582 g          674 t
ORIGIN      
        1 attgatacaa ctttttagag tagtcattag tgaacagata attgtaagtt aaccgctcca
       61 gaaatcctgg agactaaact ccctgagaaa gaggcaaaca ggatgactaa aaaaacactt
      121 ttttcccccg aagtccgtca acgggcagtt caatgctttg tcgaataaac atttacctga
      181 acgattaact gcaacggcta tccttaccga caatcaacgt caataaaaat ctgtactgac
      241 tcgtcagcac tgggttcgat cagtaggaac atgaattcaa aggccacctt gctgaatctc
      301 aagactcctc cgattccaaa gataaacccc gtcttaagtt cgctggcctg aaattcggtg
      361 actattgtct atatcgggat caccacggtt gtgtgattaa tcctcgtcga tcataaagcg
      421 tctatggatg tactgcggcg ttcctgctac tggtgatcac cctgtggttg tgcaattcca
      481 aacggctgaa gcgagagtaa cagacatcac gccgcaatcg ggggcggcgt gtagacgtgg
      541 ttaattacta tcaaatatat taatcaggcc gattctattt gctttcattt atggtttcca
      601 tcatgagctg ttgctgcttt tctttggaca gtcgagcgat accaaagcct gtgaaccccc
      661 acagcgtcgc aaagaaaatg ccactccagc agagaatagc ccacggaaga tagcttaatg
      721 tagcaacgcc aagtgtacct gccatgtagg cacccgcggc agtccagggc agaattggtt
      781 caaatatggt ggcagagtct tctacagtcc ttgccagatt ttttggatgt aggccgcgct
      841 caatataagc acttcgtagc atttcaatcg gaatcaggat tgatatctga ccattacagg
      901 tcacgctaat cattgttaaa ccacaggcaa tagtcgcaag aatcatggtt cctgtggaat
      961 gaactaattt gagcagatta tggacgatga cttctaaagc gccgctcaag gctaatgttc
     1021 ccgcaaatga aagggcgcag aaacaaataa gcaacgtact catcatcgag ttcatgccac
     1081 cgcggtttaa caaattacct aatagcggat taacatcttt atcggtaagc attgaaacgt
     1141 taaatccgtc tactgcactt ttaacaatgt cgtgtagtgc gaacccctga ataacgctgg
     1201 cgttgatcat ggctaccagt gccgaaacaa gcataattgg aatggttggt ttcttggtaa
     1261 tcgaaccgta caggacaatg gcaatgggta gcaataacaa taaattaaaa tgataaattc
     1321 cttttaatcc ttcagtgatt agctgaattt tttcgggaat ggttgagccg ccgagctcgc
     1381 tattcatccc atagagcgtc ataacaaagg ctgacagtat caatgaagga agggttgtat
     1441 aaagtaaatg agcgatgtgt tcatagagat ctatctgggc tgccattgcg gctaagttag
     1501 tatcgccaga aaggggagac agtttgtccc cgaagtaagc ccctgccaca atagcgcctg
     1561 cagttgctgc cagattagcc tccattccga tagccacacc cataaacgca acaccgacgg
     1621 tgcctgcgga tccccaggat gtccctgtgc atacagaaac gatggcagta acgagcaggg
     1681 ccgtcacata gatcatggaa ggatttatca gattaaggcc gtaataaatc atcagcggaa
     1741 tagtaccgcc tatcatccat gtcccaatca ggaggcccac gctgatcaaa attagcagag
     1801 caggcattgt tttagcgatt ttctgcgata ttgattcaag gattgcattg tagccatacc
     1861 ccaaccgctt aactaacagt gcagcaatga cggttgaaag aaccattaat ggctcaggtg
     1921 gcagatcgaa tgccgcataa ccaaatccca gcaatagtat catcgctagt attggtaata
     1981 atgattccac cagagttggg gatcttggag tattgttatt attcatgaag ggaaactcct
     2041 gtagtgaagg ggatgctctg ataaatccgt tcaaatgctt gtgtaagatt gcttctcggc
     2101 gtggctatgt tcacacggaa aaaaccaagt ccttcatcgc caaaatctga tccccagctc
     2161 atctcaacac ctgcgagcga gacaaaccaa tggcgtagtt gctcttcgct gatgttcatt
     2221 gcccggtagt cgatccacaa catgtaagtt ccgccaccag aggcgacaaa ccagtctgga
     2281 aaatgagctt ggcagaatga ttgaacccag ctcctgtttt cgaccaaata atcttttaat
     2341 gctgctaacc aagaatcgcc atggcggtaa gcacagagaa atgcaggaac agagaaataa
     2401 ccaggattat ggatacctgc tgcaataaga gctaatttaa actgttcacg atatttatcg
     2461 ttagcaataa caatatttgc gatttcaagt ccggccatat taaaagtttt tgctggagat
     2521 gtacaaataa acgagttttg tgcaacgtat gagcttatag aagaaattgt ttgatgttgt
     2581 ttttgggtga agttgaagtc tgcatgaaca
//
LOCUS       DAFGPF010000241         2597 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.245, whole genome shotgun sequence.
ACCESSION   DAFGPF010000241 DAFGPF010000000
VERSION     DAFGPF010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.245"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1049)
                     /locus_tag="LSX49_005122"
     CDS             complement(join(<1..791,791..1049))
                     /locus_tag="LSX49_005122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611153.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL7171369.1"
                     /translation="MTRRPRRNHSPAFKAKVALAAIRGEQTLVELSQQFDVHANQIKQ
                     WKDQLLEGATGVFGDETKAEPSGPTIDVKTLHAKIGELTLENGFFIRCARQGGIAGRK
                     EMIDREHKLSVVRQAKLLGFSRGSVYYLPRPVSDGDLALMRRIDELHLDYPFAGSRML
                     QGLLRGEGLETGRRHVATLMKKMGIKAIYRRPNTSKPAPGHIRKLAVTRPNQVWAMDL
                     TYIPMARGFVYLCAVVDWFSRKVLSWRLSITMEAAFCIEAVEEALARHGRPEIFNTDQ
                     GSQFTSIDFTAVLKRSQIAISMDGKGAWRDNVFVERLWRSIKYEEVYLHAYKTVSEAR
                     AGIARYLNFYNTRRPH"
     gene            complement(1141..1683)
                     /locus_tag="LSX49_005123"
     CDS             complement(1141..1683)
                     /locus_tag="LSX49_005123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7171370.1"
                     /translation="MIIWINGPFGAGKTTLAERLRDRRPKSLIFDPEEIGFVVKETVP
                     IPASGDYQDLPLWRGLTIAAVSEIRRNYSQDIIIPMTLVHPDYLTEILDGLRQIDDQL
                     LHIFLMLNEDLLRHRISNQTMHPDPNRNAEIREWRLANVARCLAARERLPSTTRVLDS
                     GAHTSDELAAMVLDRLDQRT"
     gene            complement(1696..2556)
                     /gene="aac(3)-IIe"
                     /locus_tag="LSX49_005124"
     CDS             complement(1696..2556)
                     /gene="aac(3)-IIe"
                     /locus_tag="LSX49_005124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(3)-IIe"
                     /protein_id="HBL7171371.1"
                     /translation="MHTRKAITEAIRKLGVQTGDLLMVHASLKAIGPVEGGAETVVAA
                     LRSAVGPTGTVMGYASWDRSPYEETLNGARLDDKARRTWPPFDPATAGTYRGFGLLNQ
                     FLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLG
                     APLNSVTALHYAEAVADIPNKRWVTYEMPMLGRNGEVAWKTASEYDSNGILDCFAIEG
                     KPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGATPIVPAHE
                     AAQRSCEPSG"
BASE COUNT          514 a          795 c          718 g          570 t
ORIGIN      
        1 atgtgggcgt ctggtgttgt agaagttcag atatcgggcg atgccagcgc gtgcctcgga
       61 cacagtcttg taggcatgga ggtagacttc ctcgtatttg atcgaacgcc agagccgctc
      121 gacgaagaca ttgtctcgcc acgcaccctt gccatccatc gagatggcaa tctgtgacct
      181 cttcagcacg gcggtgaagt cgatggaggt gaactgcgat ccctggtcgg tattgaagat
      241 ttccggcctg ccatgacggg caagtgcctc ctccaccgcc tcgatgcaga aggctgcttc
      301 catcgtgatc gacaaccgcc atgacaagac cttccggctg aaccagtcca cgacggcgca
      361 cagatagaca aatccccgcg ccatggggat gtaggtcagg tccattgccc acacctgatt
      421 gggccgggtg actgccagct ttcgtatgtg ccctggcgct ggtttcgagg tgttcgggcg
      481 gcggtagatc gccttgatgc ccatcttctt catcagcgtg gcgacgtgtc gccgcccggt
      541 ctccagacct tctcctctca agagcccttg caacatccga cttccggcaa aggggtagtc
      601 gagatgcaat tcgtcaatcc ggcgcataag ggccagatcg ccgtcagaca ccggacgagg
      661 cagatagtag acgctgccac ggctgaagcc gagaagcttc gcctggcgca cgacggatag
      721 cttgtgctcg cggtcgatca tttctttccg cccagcaatc ccgccttgcc gagcgcaccg
      781 gataaaaaat cgttctccag tgtcagttcg ccgattttcg cgtgcagcgt tttgacatcg
      841 atggtcggac ccgacggctc cgctttcgtt tcatcgccga acacacctgt cgccccctca
      901 aggagctggt ctttccattg cttgatctgg ttggcgtgca catcgaactg ctgggacaac
      961 tccaccagcg tctgctcacc tcggatggcg gcaagtgcca ccttcgcctt gaaagccggg
     1021 ctatggttcc ggcgcggtcg tctcgtcatg gtctctcctg ttcccggcat ctaagccgaa
     1081 gtcaggcaga aactccactt atccccgctg tgcagatttc ccgagccagc tctaaggcga
     1141 tcaggtgcgc tgatcgagtc tgtcgagcac catcgctgca agttcatcgc tggtgtgtgc
     1201 accactatcg agaacacggg ttgtggacgg aagccgttcc cttgcggcca agcatcgggc
     1261 gacattcgct aatcgccact ctcgaatctc cgcattccga ttcgggtcag gatgcatggt
     1321 ctggttcgag atccggtgac gcaataggtc ctcgttaagc atcagaaaga tgtgcagcag
     1381 ctgatcgtcg atctgcctta acccgtcgag tatctcagtc agatagtccg ggtgcacgag
     1441 cgtcattggg atgatgatgt cctgcgagta attcctgcga atctcgctga ccgcagcgat
     1501 cgtaagtccc ctccacaagg ggagatcctg atagtctccg ctcgctggta tggggaccgt
     1561 ttctttcacc acgaacccga tttcctcagg gtcaaagatc agcgatttcg gacgccgatc
     1621 gcgcagccgc tcagcgagag tcgtctttcc ggcgccgaaa ggtccgttga tccagattat
     1681 cattgtcgac ggcctctaac cggaaggctc gcaagagcgc tgggcggctt cgtgtgctgg
     1741 cacgatcgga gtggctccga agtgcttctc aagataggtg acgccgaacg tcacgatgtc
     1801 ctgcgcgtcg aacaggtagc actgagcaaa gcccacgaca ccttctcgat ggcgaccgag
     1861 cttcacgtaa gcatttgcta tagtttcgac cgcatccggc tttccttcga tagcaaagca
     1921 atcgagaatg ccgtttgaat cgtattctga tgccgttttc caggcgactt caccgtttct
     1981 tccaagcatc ggcatctcat acgtcaccca tcgtttgttg gggatatccg caaccgcctc
     2041 ggcgtagtgc aatgcggtaa cggagtttag cggcgcaccc aacagcaggg ccttcccgcc
     2101 aaggcggacg aaccgctcga cgggcgaccc ttcccccaag gcgtgaccga gttcgtgagg
     2161 ctccgtcagc gtttcagcta gcggaccaac cgcgaccatc gatgcatcgg ggtgcgcgct
     2221 gcgccgcgcg ccgggggctt gaaccagaaa ttgattcagc aggccgaacc cacggtaagt
     2281 cccggccgtt gcgggatcga acggcggcca ggtacggcgg gctttgtcat ccaaccgagc
     2341 gccattcaga gtctcctcgt agggtgatcg gtcccacgac gcgtatccca tcacagtgcc
     2401 agtcggccca accgcggagc gtaacgcggc aacgaccgtc tccgctcctc cttcgaccgg
     2461 accaatcgct ttaagtgagg catgcaccat caacaggtca ccggtttgga ctcctaattt
     2521 tcgaattgcc tccgttattg ccttccgcgt atgcatcgcg atatctcctc taaactgcaa
     2581 aacactatac ctatcga
//
LOCUS       DAFGPF010000242         2597 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.246, whole genome shotgun sequence.
ACCESSION   DAFGPF010000242 DAFGPF010000000
VERSION     DAFGPF010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.246"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            350..493
                     /locus_tag="LSX49_005125"
     CDS             350..493
                     /locus_tag="LSX49_005125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HBL7171372.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
     gene            506..715
                     /gene="cspE"
                     /locus_tag="LSX49_005126"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             506..715
                     /gene="cspE"
                     /locus_tag="LSX49_005126"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HBL7171373.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            881..1690
                     /gene="rlmA"
                     /locus_tag="LSX49_005127"
     CDS             881..1690
                     /gene="rlmA"
                     /locus_tag="LSX49_005127"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HBL7171374.1"
                     /translation="MSFSCPLCHQPLLREKNSYICPQRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLREWLDEKATAVLDIGCGEGYYTHA
                     FADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELVRVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLKGFTLQQSDELCY
                     LMRLRGDEAVALLQMTPFAWRAKPEVWQALAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(1687..2253)
                     /gene="mntP"
                     /locus_tag="LSX49_005128"
                     /pseudo
     CDS             complement(1687..2253)
                     /gene="mntP"
                     /locus_tag="LSX49_005128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
BASE COUNT          707 a          590 c          613 g          687 t
ORIGIN      
        1 tgatacccgt taactgactg ttttatgaga aaaagtgata taacttttta ttcattgcat
       61 agtagaaaat gtgatattgc acgcactatg taataacttc tcccactggc ctggaacaac
      121 tgaacttatt gaactatgtt agaaaatacg tcagtttaag tatctgcctg aactggcaag
      181 gttaagcaca atgatatatc ggcgcgtatt ccgttgcata agtgtgcaaa aaaagtggaa
      241 gacgtatcga gatttgtgcg tctgatcgag acatgtttaa aaatggcttg ccataattaa
      301 cgttgtatgt gataacagat ttcgggttaa acgaggtaca gttctgttta tgtgtggcat
      361 tttcagtaaa gaagtcctga gtaaacacgt tgacgttgaa taccgcttct ctgccgagcc
      421 ttatattggt gcctcatgca gtaatgtgtc agttttatct atgttatgcc tgcgggcgaa
      481 gaaaacaatc taaggaattt ttcaaatggc aaagattaaa ggtcaggtta agtggttcaa
      541 cgagtctaaa ggttttggct tcattactcc ggctgatggc agcaaagatg tgttcgtaca
      601 cttctccgct atccagggta atggtttcaa aactctggct gaaggtcaga acgttgagtt
      661 cgaaattcag gacggtcaga aaggtccggc agctgttaac gtaacagcta tctgatcgaa
      721 tccactgatc tgaagtgtga atacgcttca atctcgctat aaagcctcgt cgaatgcgag
      781 gctttttact ttgttttatc ttcgctccag tcgttcggat atttgcccgc cgcatgattc
      841 gcgttacact tgcggccttt agtatcctgc cggagttgtc atgtcgtttt cctgtccact
      901 ttgccatcag cctcttttgc gtgaaaaaaa cagctatatc tgtccccagc gacatcagtt
      961 tgatatggcg aaagaagggt atgtcaatct gctgcccgtt cagcataaac ggtctcgtga
     1021 tccgggcgac agcgcggaaa tgatgcaagc acgccgcgca ttcttagatg ccggacatta
     1081 tcagccgctg cgtgatgcaa ttgtcgccca actgcgggaa tggcttgatg aaaaggccac
     1141 ggcggtgctg gatattggct gtggtgaagg gtattacaca cacgcatttg ctgatgcgtt
     1201 gcccgaaatc accacgtttg gcctggatgt ctcgaaggta gcgataaaag cggcggcgaa
     1261 acgctatccg caggtcactt tttgtgtcgc ttccagccac cgtttgccgt tttccgatac
     1321 cagtatggac gccataatac gtatttacgc gccgtgtaaa gcagaagaat tagtgcgagt
     1381 agtgaagccc ggcggttggg tcattactgc cacgccggga ccgagacact taatggagct
     1441 gaaggggctg atttacaatg aagtacatct tcatgcacct catgcagaac aactgaaagg
     1501 ttttacatta cagcagagtg atgagttgtg ttatctgatg cgtcttcgcg gtgatgaagc
     1561 cgtcgcatta ttgcagatga cgccgtttgc ctggcgtgcg aagcctgaag tctggcaagc
     1621 actggcagca aaagaagtgt tcgactgcca gacggacttt aatattcacc tctggcagcg
     1681 ttcttattaa ccgtggaagt gcgtccagag gatctggacg ccaataccga tcagtaccag
     1741 cccaccgaga atttccgctt ttttcccaat aattgagccg ataaagcgac caaccatcat
     1801 ccctaatgtc gacataatca aggttgcaca accaatggcc aatgcggtcg cgataatgtt
     1861 aacctgcagg aaagcaagac caacacccac agccatggca tccaggctgg tggcaatcgc
     1921 ggtggttacc agtagtcaga aaccgtgtcg acggcgcggt tcttcatctt catcatctgc
     1981 gccacgaaaa ccctcaataa tcattcgccc gccgagaaat atcagcagca caaacgcaat
     2041 ccagtggttc cattcaagga caaaccgact ggctaacatg cccattcccc agccgatcag
     2101 cggcgtcagg gtttcgacgg caccaaaaat aaggccggtt cgcaatgctt cagaaaattt
     2161 cggtttatgg agggtggcac ctttaccgat tgatgcagca aaggcatcca tcgacatacc
     2221 aaacgcaaga agaacagtag cagtgatatt catgacaacg tcctgaccgg ggtatccata
     2281 aaacacatca tcgcccccag caaacatgca tacatgaaca acaagccgcg atggttttcg
     2341 cgttcatgca ggcatagcga ttgatgtgca tatggtctcg cctgactgaa agtgttcagt
     2401 ccgtacgtgc cacgttttgc aacgagtatg ttgacacgta catttccgga atctggaaat
     2461 cagctactcc ccaaatgagg gcgcaacctt aacatatttt gagaatataa gacaactgtt
     2521 ggaatatatt attttattgt tttattgata acgattttca tttagattta tatatcaatg
     2581 aaacgttaaa ataaata
//
LOCUS       DAFGPF010000243         2530 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.247, whole genome shotgun sequence.
ACCESSION   DAFGPF010000243 DAFGPF010000000
VERSION     DAFGPF010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2530
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.247"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..915
                     /locus_tag="LSX49_005129"
     CDS             <1..915
                     /locus_tag="LSX49_005129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2345 domain-containing protein"
                     /protein_id="HBL7171375.1"
                     /translation="DHVTIQNYKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQL
                     NLGHLVDAGKQQRGEGFELRTDLWGAVRAKKGIFISADAQDKAQGQVREMADIISELN
                     SLSDKIQKLSDDAATANADPADMAAQVALITSRINDLTASVILMHAPKGVAVASGEHL
                     QLAAVKNLQINAGNNADIGVVKNMFIGVGRALSVFVRKAGIKLIANKGAVSVQAQHDL
                     MELLAKKSIEIVSTEDEIRISAKKKITINGGGSYIRIEGSGIEPGTPGDYNVKAVHYG
                     RMGKAHEPVELQMLAEKVDEPPVKFFFS"
     gene            927..>2530
                     /locus_tag="LSX49_005130"
     CDS             927..>2530
                     /locus_tag="LSX49_005130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family peptidase"
                     /protein_id="HBL7171376.1"
                     /translation="MIISPPFIRAKNNNENDAHWIERMMPVEPDRDYPINYGGSWHGG
                     IHVRHTNSDRQPEYVRAIADGVVVSIRNPSDQAACSLPPLNYNGSTDDGYVLLRHETE
                     IGTGEDGNIVYYSLYMHLEKIEEGISEGNKVYRKSSLGMPGHVDGDRGLHFQIFCDDD
                     NLRKITGRTTPEMDVSRHGRTDVVYGDIYFYLPPGTRFYRSAPENNAVDNTGEVFQST
                     EPLVVTMCFDTGHCIMTTRRANPVIPSRYDIVGEVLTDADGTDYEYNLYSAALRLYPQ
                     SPSAGFELLRFGRVINTEHETLIPANAPLWRTVSYPGGQGVINLAADVVTKFSDGDFP
                     HWSGWRLVDDDADSNSQCNSVILRGGGFTDFRQMICHFPLEWCNTGIEARYGWLKEGV
                     IQERQENEANSDLSLGTDYYRPNNVEYNTTGDSHGESPQSAISEMPDLSYEQSNAYEN
                     AVRVLLLGEEDWQTLVKHIKALCFDTSSIAEGRVWHFNPGEFIKHFRKCGWVDKAILK
                     RIFASGTNDRDRAVIEQKVDIYGTAI"
BASE COUNT          713 a          516 c          719 g          582 t
ORIGIN      
        1 gaccatgtga ccattcagaa ctacaagcgt aacgtgctgc gcaccccggc gaacaacaaa
       61 atccgcctcg acgatgagcg cggcaaagag catatcaagg tcagtaccga gtacggcggc
      121 aagagccagc taaacctcgg ccatctggtg gatgccggaa aacagcagcg cggggaaggt
      181 tttgaactgc gtaccgatct gtggggtgca gtacgggcaa agaaaggcat ctttatcagc
      241 gccgacgcgc aggataaggc gcagggtcag gtacgcgaaa tggccgacat tatcagcgaa
      301 ctgaacagcc tgagcgataa aatccagaaa ctgtctgacg atgcggccac ggcgaacgcc
      361 gatccggcgg atatggccgc gcaggtggcg ctgataacca gccggataaa tgacctgacc
      421 gcctcggtga ttttgatgca cgcgccgaaa ggtgtggcgg tcgccagcgg cgagcacctg
      481 caactggccg cagtgaaaaa cctccagata aatgcgggaa acaacgccga tatcggcgtg
      541 gtgaagaata tgtttatcgg cgtagggcgg gcgctgagcg tgtttgtgcg caaggcgggt
      601 atcaaactga ttgccaataa aggcgcagta tcggtacagg cgcagcacga tctgatggag
      661 ttactggcga agaagtcgat agagatcgtc agtactgagg acgagatcag gatttcagcg
      721 aagaaaaaaa taacgattaa tggtggtgga agttatatcc ggattgaggg tagcggcatt
      781 gagccgggaa cgccggggga ttataacgtc aaagcggtgc attacgggcg tatgggaaaa
      841 gcacatgagc ctgttgagtt acaaatgttg gcagagaaag tagatgagcc acccgtaaaa
      901 tttttctttt cttaaggata taagaaatga ttattagccc gccatttata cgagcgaaaa
      961 ataacaatga aaacgatgct cattggattg aaaggatgat gccagttgaa cctgaccgtg
     1021 actatcccat caactatggg ggatcatggc atggaggcat ccacgttaga catacaaaca
     1081 gtgacaggca accagaatat gtccgtgcca ttgctgatgg tgtcgtggta tctattcgca
     1141 atccctctga ccaggcagca tgtagtcttc cgccgctcaa ttataatgga agcacagacg
     1201 atgggtatgt tctgcttcgt catgaaactg aaataggcac tggtgaggac ggcaatattg
     1261 tttattactc tctttacatg cacctggaaa agattgaaga gggtatcagt gaaggaaata
     1321 aagtctaccg gaaatcgtca ctgggaatgc cggggcatgt cgacggggat cgcggcctgc
     1381 acttccaaat tttctgcgat gatgacaatc tgagaaaaat aaccgggcgc actacacctg
     1441 agatggatgt gagccgtcat gggcgtaccg acgtggttta cggggatatc tatttttacc
     1501 tgccgcccgg tacccgcttt tacaggagtg cgccggaaaa caacgcagta gataacacag
     1561 gtgaagtttt tcagagcacg gaaccgttgg ttgtcaccat gtgttttgat actggccatt
     1621 gtatcatgac tacccgcaga gcaaatccgg tgataccaag ccgttatgac attgtgggag
     1681 aagtgttgac ggatgctgac ggcactgatt atgaatacaa cttgtacagt gctgcactga
     1741 gactttatcc gcaaagtcca agcgcagggt ttgagttact gcgctttggt cgggttatca
     1801 ataccgagca tgaaacactg atacccgcga atgcgccact gtggcgaacc gtgagctatc
     1861 ccggtgggca aggagtgata aatctggcgg cagatgttgt gacaaaattt agcgacggtg
     1921 attttccgca ctggagtggc tggcgactgg tagatgacga cgctgacagc aacagtcagt
     1981 gcaattcagt aatattacgt ggtggtggtt ttacggattt tcgtcagatg atttgccact
     2041 tcccactgga gtggtgtaat acgggaatag aagcgcgtta cggctggttg aaagaagggg
     2101 taatacagga acgtcaggaa aatgaggcta acagcgattt atcattaggt acggattact
     2161 acaggccaaa taatgtcgaa tataatacga ctggagatag ccatggagaa tctcctcagt
     2221 cagctatatc agaaatgcca gatttgtctt atgaacagtc aaatgcttat gaaaatgccg
     2281 tcagagtttt attactggga gaagaagact ggcagacgtt ggtgaagcat attaaggcac
     2341 tgtgttttga taccagtagt attgctgaag gacgggtttg gcattttaat ccgggtgagt
     2401 ttattaagca ttttaggaag tgtgggtggg ttgacaaagc aatattgaag cgaatttttg
     2461 cctctggtac taatgaccgt gatagagcgg ttattgaaca aaaagttgat atatatggta
     2521 cggctataaa
//
LOCUS       DAFGPF010000244         2498 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.248, whole genome shotgun sequence.
ACCESSION   DAFGPF010000244 DAFGPF010000000
VERSION     DAFGPF010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2498
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.248"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            88..576
                     /gene="eco"
                     /locus_tag="LSX49_005131"
     CDS             88..576
                     /gene="eco"
                     /locus_tag="LSX49_005131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HBL7171377.1"
                     /translation="MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQV
                     IQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVS
                     TMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAV
                     VR"
     gene            complement(726..2372)
                     /gene="mqo"
                     /locus_tag="LSX49_005132"
     CDS             complement(726..2372)
                     /gene="mqo"
                     /locus_tag="LSX49_005132"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HBL7171378.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNSWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEVLKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL"
BASE COUNT          610 a          667 c          611 g          610 t
ORIGIN      
        1 taaagcaaat taataaatct gatgaatatg ttaaccttca gcgacatcat cggtgaaaac
       61 ctataaatga agaaggaaag caaaaaaatg aagaccattc tacctgcagt attgtttgcc
      121 gctttcgcca ccacttccgc ctgggcggca gagagcgtcc agccactgga aaaaatcgcg
      181 ccttatccac aagctgaaaa aggcatgaag cgtcaggtga ttcagttaac tccgcaagaa
      241 gatgaatcta ccctgaaagt agaactgtta atcggtcaga cgctggaagt cgactgcaat
      301 ttgcatcgtc tcggcgggaa gctggaaagc aaaacgctgg aaggctgggg ctatgattat
      361 tatgtctttg ataaagttag ctcgccggtt tccacgatga tggcctgccc ggatggcaag
      421 aaagagaaga aatttgtcac cgcgtatctg ggcgatgctg gaatgctgcg ttacaacagc
      481 aagctgccga tcgtggtgta tacgccagac aatgtggatg tgaagtaccg tgtctggaag
      541 gcggaagaga aaattgacaa cgcggttgtt cgctaaactg ctttgaagtg ctgcaacctg
      601 taggccgaat aaggcggtta cgccgcatcc gacatctaac gcccgagccg gttgcctgat
      661 gcgacgctga agcgtcttat cagcatacgc cacatccggc aaaccatgcc ggatgtggca
      721 catcattaca acgcaatatc cgccacttct ttttgaacgg gttgcggttt caactgcggt
      781 ttcggcgtac tatctgctgc ctgcggcttg tcgtatttca gacccagcac ttcgctggtg
      841 tactgcaact cgcgttctgt tgccgctaca tcaccgttca gcttgcgtcc ataagacgga
      901 acgatcgctt tcaacgtagc ctgccattgc gggctggaaa cgcgatcgcc aaatactttt
      961 tccagcagat tcaacataat cggcgcggcg gttgacgccc ctggcgatgc ccccaggagc
     1021 gcggcaatgg tcccttgctg gtcactgacg acttcagtac cgagacgcag tacgccacct
     1081 ttatcggcat cacgcttgat aatctgcacg cgctgccccg cttgccacaa acgccagtcc
     1141 tcttttttcg cctgcggata gtactctttc aacacttcaa aacgatcctc ttcactcaac
     1201 atcacctgac tcaccagata tttcaccaga tcgaaattat ccagcccaac gtgcatcatc
     1261 ggcatcacgt tagaggtggt ggtggaactc atcagatccc ataatgaacc gtttttgagg
     1321 aatttggttg agaaggtggc aaatggccca aacagcacta cgcgtttacc gtcaagaaca
     1381 cgggtatcga tatgcggaac cgacatcggt ggtgcgccaa cggatgcttt accgtaaacc
     1441 ttcgccagat ggtgattaac cacgtccggg ttttccgaaa caaggaactg tccgcccacc
     1501 gggaaaccag cgtagtcttt cgcctccgga atccccgatt cctgtaacag tttcagcgcc
     1561 gcaccgcccg cgccgataaa gacaaatttg gcgcggatgt tctgtgcagt gccgtttttc
     1621 agatcggcaa cggtgacggt ccagctgtta tcgtcattac gctttagggc gcggacttcg
     1681 ctgctgagtt gcagcgagaa gttagatttc ttctgtaagg aggcgatcaa ctggcgggtg
     1741 atctcgccat agttcacatc ggtgccaatt tctgtgcgtg ttgccgctac tttctgttgc
     1801 ggatcgcgcc cttccatcac taacggtgcc cactctttga tctgcgcgtg atcttcagag
     1861 taacgcatac cgcgaaacag cgagctttgt tgcaacgcgg cgtaacgggc gcgcaggaaa
     1921 ttaacgttat cctcgcccca gacaaagctc atatgcggaa cggtattgat aaatgaacgc
     1981 ggagtacgca gcacaccacg ctcgacctgg tgcgcccaga actggcggga aatctgaaat
     2041 gcttcgttaa tggcgactgc tttttcaata ctgatactgc cgtcggcatt ttgcggggtg
     2101 taattgagtt ccatcagtgc agaatgcccg gttccggcgt tgttccagcc gttcgaactc
     2161 tcctgcgcga caccttccag gcgctccacc atggtcatcg accattcagg ctccagctcg
     2221 cgtaaatagg tccccaacgt ggcgctcata atgccgccgc caatcaacag tacatcagtt
     2281 tcctgctcct cggacgcttt cgcttttgcc gccatcgaaa cggcattaag ccccacggcc
     2341 atcgagaaga gcatggcagt cacttttttc atcttgttaa tgccttactt ttagtcgctt
     2401 tattgcaggt gagatttgcg cggcatcaac ggtaacactt aagtaacaac atttaaataa
     2461 tgtttataaa ttatattcta attttagaaa cattataa
//
LOCUS       DAFGPF010000245         2426 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.249, whole genome shotgun sequence.
ACCESSION   DAFGPF010000245 DAFGPF010000000
VERSION     DAFGPF010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2426
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.249"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            49..474
                     /locus_tag="LSX49_005133"
     CDS             49..474
                     /locus_tag="LSX49_005133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL7171379.1"
                     /translation="MELQDWRKEPRKNYSNEFKLRMVELASQPGACVAQIARENGVND
                     NVIFKWLRLWQNEGRVSRRLPVTTSSDTGVELLPVEITPDEQKEPVAAIAPSLSTSTQ
                     TRVSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
     gene            471..821
                     /gene="tnpB"
                     /locus_tag="LSX49_005134"
     CDS             471..821
                     /gene="tnpB"
                     /locus_tag="LSX49_005134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL7171380.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLF
                     IFRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPAVRDGKVSITRSQLAMLLDKLDW
                     RQPKTSSRNSLTML"
     gene            852..>2426
                     /locus_tag="LSX49_005135"
     CDS             852..>2426
                     /locus_tag="LSX49_005135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc23 family transposase"
                     /protein_id="HBL7171381.1"
                     /translation="MSQKYLIRIAELERLLSEQAEALRQKDQQLSLVEETEAFLRSAL
                     TRAEEKIEEDEREIEHLRAQIEKLRRMLFGTRSEKLRREVELAEALLKQREQDSDRYS
                     GREDDPQVPRQLRQSRHRRPLPAHLPREIHRLEPEESCCPECGGELDYLGEVSAEQLE
                     LVSSALKVIRTERVKKACTKCDCIVEAPAPSRPIERGIAGPGLLARVLTGKYCEHLPL
                     YRQSEIFARQGVELSRALLSNWVDACCQLMTPVNDALYRYVMNTRKVHTDDTPVKVLA
                     PGQKKAKTGRIWTYVRDDRNVGSSSPPAVWFAYSPNRQGKHPEQHLRPFRGILQADAF
                     TGYDRLFSAEREGGALTEVACWAHARRKIHDVYISSKSATAEEALKRISELYAIEDEI
                     RGLPESERLAVRQQRSKVLLTSLHEWMVEKNGTLSKKSRLGEAFSYVLNQWDALCYYS
                     DDGLAEADNNAAERALRAVCLGKKNFMFFGSDHGGERGALLYGLIGTCRLNGIDPEAY
                     LRHILSVLPEWPSNRVD"
BASE COUNT          616 a          604 c          686 g          520 t
ORIGIN      
        1 gagaattggt aacttagacg cccatctgat atagacggac atctaagtat ggaattacag
       61 gactggcgaa aagaacctcg taaaaactat tcgaatgaat tcaaacttcg tatggtggaa
      121 ctggcatcac aacctggagc ttgtgttgca cagattgcac gtgaaaatgg cgtcaatgat
      181 aatgttattt tcaaatggct caggctctgg cagaacgaag ggcgtgtttc gcggcgtctt
      241 ccggtaacga cctcttctga cactggcgtt gaattattac ctgtagaaat aacgccggat
      301 gagcagaaag aacctgtggc ggccattgcg ccgtctttat ccacttccac tcagaccaga
      361 gtcagtgcca gttcctgcaa ggtggaattc cgtcacggta acatgacgct ggaaaatcca
      421 tcgccagagc tgctcacagt gttgatccgt gaactgaccg ggaggggaag atgatctcac
      481 tcccatcagg tacccgtatc tggctcgttg ccggcgttac cgatatgcgt aaatccttca
      541 acggactggg agaacaggta caacatgtgc tgaatgataa tcccttctcc ggtcacctgt
      601 ttatcttccg tggccgacgg ggtgacaccg tcaaaattct ttgggctgat gctgatggtc
      661 tgtgcctgtt caccaaacgc ctggaggaag gccagtttat ctggcctgcg gtacgtgacg
      721 gcaaggtatc cattacccgc tcgcaactgg caatgctcct cgataagctg gactggcgtc
      781 agccaaaaac atccagccgt aactcactga caatgttgta aaaaactcct gaccgcatta
      841 taaaaacggt catgagtcag aaatacctca ttcgcatcgc agagctggaa aggttgctct
      901 ctgagcaggc tgaagccctc cgtcagaaag accagcaact gagtctggtt gaagagacgg
      961 aagccttcct gcgctctgca ctgacacgtg ccgaagaaaa gatcgaagaa gatgaacggg
     1021 aaatagaaca tctgcgggct cagatagaaa aactgcgccg gatgctgttc ggtacccgtt
     1081 ctgaaaaact gcgtcgtgaa gttgaactgg ctgaggctct gctgaaacaa cgtgaacagg
     1141 acagcgatcg ttacagtggg cgggaagacg atcctcaggt tccccgccag ttgcgacagt
     1201 cgcgccatcg tcgtccgtta ccggcacacc ttccccgtga aatacaccgc ctggagccag
     1261 aagaaagctg ttgcccggag tgtggcggtg agctggatta tctgggggaa gtcagcgctg
     1321 aacagctgga actggtgagc agtgccctga aagtgatccg cacagaacgg gtaaaaaaag
     1381 cctgtacaaa atgtgactgt attgttgaag caccggcgcc gtcccgcccg atagagcgtg
     1441 gtatcgcggg ccccggatta cttgcccgcg tgttaacggg aaaatactgc gaacatctgc
     1501 cactgtatcg tcagagtgaa atctttgccc gccagggtgt cgaactgagc cgggccttac
     1561 tctccaactg ggttgacgcg tgctgccagt taatgacacc ggtgaatgat gccctgtacc
     1621 gttatgtaat gaacacccgc aaggttcaca ctgatgacac accggtaaag gtactggcac
     1681 cgggtcagaa aaaggcgaaa acagggcgta tctggacgta tgtccgggat gatcgcaatg
     1741 tgggttcgtc atctcctcca gcggtctggt tcgcgtactc gccgaaccgg caggggaaac
     1801 acccggagca acacctccgc cccttccggg gtatcctgca ggcggatgcg ttcacaggtt
     1861 acgacaggtt gttcagtgca gaacgtgaag gtggtgcact gacagaagtt gcgtgctggg
     1921 cccatgcccg gcgaaaaatc cacgatgtat acatcagcag caaaagtgcg acggcagaag
     1981 aagccctgaa gcgaatcagt gaactgtacg ccatcgagga tgaaatacgg ggattaccgg
     2041 agtcagagcg tcttgccgtc aggcagcagc gaagcaaagt gttactgacg tcgctgcatg
     2101 aatggatggt ggagaagaat ggtacgctgt cgaaaaaatc cagactgggc gaagcgttca
     2161 gctatgtact gaatcagtgg gatgccctct gttattacag tgatgacggt ctggcggagg
     2221 cggataataa tgctgcggaa agagcgcttc gtgcagtctg tctcggaaag aaaaacttta
     2281 tgttctttgg cagcgatcac ggcggcgagc gtggagcact gttgtacggg ctgatcggca
     2341 cctgccgtct gaacggtatc gatccggaag cgtatctgcg ccatatcctg agcgtactgc
     2401 cggaatggcc ttccaaccga gttgac
//
LOCUS       DAFGPF010000246         2378 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.250, whole genome shotgun sequence.
ACCESSION   DAFGPF010000246 DAFGPF010000000
VERSION     DAFGPF010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2378
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.250"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..183)
                     /gene="ariR"
                     /locus_tag="LSX49_005136"
     CDS             complement(<1..183)
                     /gene="ariR"
                     /locus_tag="LSX49_005136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm/acid-resistance regulator AriR"
                     /protein_id="HBL7171382.1"
                     /translation="MLEDTTIHNAISDKALSSYFRSSGNLLEEESAVLGQAVTNLMLS
                     GDNVNNKNIILSLIHSL"
     gene            complement(212..484)
                     /locus_tag="LSX49_005137"
     CDS             complement(212..484)
                     /locus_tag="LSX49_005137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HBL7171383.1"
                     /translation="MKTSDNESIKYEITGQAVLQILRMKINFSLQTLIKQLLVMKSAE
                     ENTFRRDLIDSIIRDFSNSDTGGPNRRTAIADNKNMFTGKKINRIH"
     gene            complement(527..763)
                     /locus_tag="LSX49_005138"
     CDS             complement(527..763)
                     /locus_tag="LSX49_005138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YcgZ"
                     /protein_id="HBL7171384.1"
                     /translation="MHQNSVTSDSAGAITRYFAKANLPTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLCRLEQATGEEEQKHYNALIGLLFE"
     gene            1077..2288
                     /gene="bluF"
                     /locus_tag="LSX49_005139"
     CDS             1077..2288
                     /gene="bluF"
                     /locus_tag="LSX49_005139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HBL7171385.1"
                     /translation="MLTTLIYRSHIRDAEPVKKIEEMVSIANRRNMRSDVTGILLFNG
                     SHFFQLLEGPEEQVQMIYRAICQDPRHYNIVELLCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQSTYFEIPAEDSWLFIADGSDKE
                     LDSCTLSSNINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKEGEIYTAD
                     LKSKALAFAMAHALKLGDKMISINLLPMTLVNEPDAVSFLLDEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAVKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIMKCCTSLEIQVSAMGVATPEEWMWLESAGIEMFQGDLFSKAKLN
                     GIPSVAWPEKK"
BASE COUNT          699 a          485 c          450 g          744 t
ORIGIN      
        1 cagggagtgt atcagactta agataatatt tttattatta acattatcac ctgaaagcat
       61 taaattggtc acagcctgcc ctaacacagc tgactcttct tctaacaaat tacctgaact
      121 acgaaagtaa cttgataacg ctttatcaga tattgcatta tgaatagtag tatcttcaag
      181 catggtaacc tctcatctta cttatgaaat tttaatgtat tctgtttatt ttcttaccag
      241 tgaacatatt tttattgtca gcgatcgctg ttcttcggtt tggccctcct gtatcactgt
      301 tgctaaaatc acgaattatg ctgtcaatta aatctcgtcg gaaagtattt tcctcagccg
      361 atttcattac gagtaattgc ttaataagag tctgcaacga aaaatttatc ttcatgcgca
      421 gtatctggag caccgcctgg ccagtaattt catatttaat actttcatta tcagatgtct
      481 tcataacgac ttcatagcta acctgttaaa taatcaggct gttgcattat tcaaaaagca
      541 acccaattag tgcattataa tgtttctgtt cctcttcccc tgtcgcttgt tccagtcggc
      601 aaagaagttt ggcacaaagc gactttcgac tcagattacg tccatctttc aaaatctcag
      661 tcacaatttc cccgagagtt tcctgctgag taggcaagtt agcttttgca aagtaacgag
      721 tgattgctcc tgcagaatct gaagtcactg aattttgatg catgctacgc ctctgttaaa
      781 aatgttaatc aatgttaagt gaggtaacaa tagcaaactt gtacgaaata tgtgtacaga
      841 atgataaatt aatttttcgc aattagtgct aattcatata aaacaatgca ttacgataaa
      901 acatattgca tcatttaaat gacaacctat acaggttttt tcaccaaacc gtcttcaacc
      961 ttttccactt tttatcaatg taaagaaacg gttatgtttt ggtattaaaa gaaagacaca
     1021 agaagatatg tctgttaccg tcttactctc gcctcgccca ttaccctgga ttgttaatgc
     1081 ttaccaccct tatttatcgt agccatatac gtgacgccga acctgtcaaa aaaatcgaag
     1141 aaatggtttc gatagcaaat cgcaggaaca tgcggtctga cgtaacaggg atcttactgt
     1201 ttaatggttc tcattttttc cagcttctgg aaggtccgga agaacaggtt caaatgatat
     1261 atcgggccat atgccaggat ccacggcact ataatattgt tgaactgttg tgcgattacg
     1321 cgcctgctcg ccgttttggc aaagcaggaa tggaattatt tgatttacgc ctgcacgagc
     1381 gagatgacgt tttacaggcc gtattcgaca aaggcacatc aaaatttcag ctaacttatg
     1441 atgacagagc gctacaattt tttcgtactt ttgtccttgc aactgaacaa tcaacctatt
     1501 tcgagattcc tgctgaagac tcctggcttt ttatcgctga cggatctgat aaagaacttg
     1561 attcttgtac cctttcatca aatataaacg accactttgc ctttcatcct attgtcgacc
     1621 ctttatcgcg gcggataatc gcttttgaag ccattgtgca aaaaaatgaa gacagcccgt
     1681 cagctatagc ggttgggcag cgtaaagaag gggaaatcta cacagcggat ctcaaaagta
     1741 aggcgcttgc attcgcgatg gcacacgcac ttaagctcgg tgataaaatg atttcaatca
     1801 atctattacc tatgaccctg gttaacgagc ctgacgcagt ctctttttta cttgatgaaa
     1861 taaaggccaa tgctctggtg cctgaacaaa tcatcgttga atttactgaa agtgaagtca
     1921 tatctcggtt tgatgagttt gccgaagcgg ttaaatcgct aaaggctgcc ggtatcagtg
     1981 tagcaattga tcattttggc gcaggttttg ctggtttgtt actcctgtca cgcttccagc
     2041 ctgacagaat taaaatcagt caggaattga ttaccaacgt tcataaaagc ggaccacggc
     2101 aggcaattat tcaggcgatc atgaaatgct gtacatcact tgaaattcaa gtctctgcta
     2161 tgggcgtggc aacaccagaa gagtggatgt ggcttgaatc tgcaggaatt gagatgtttc
     2221 agggagatct gttttccaaa gctaaattga atggtatccc ttcagttgcg tggccggaga
     2281 aaaaataatt ttcagcacat tatttcgcat gatttctgga aatcatcgtg aaaatgaata
     2341 cgttatgttt taatttaatc cacattaaaa ataatatt
//
LOCUS       DAFGPF010000247         2376 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.251, whole genome shotgun sequence.
ACCESSION   DAFGPF010000247 DAFGPF010000000
VERSION     DAFGPF010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2376
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.251"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            130..1911
                     /gene="hcp"
                     /locus_tag="LSX49_005140"
     CDS             130..1911
                     /gene="hcp"
                     /locus_tag="LSX49_005140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HBL7171386.1"
                     /translation="MGDIVYLRIIGEKQGDISSGCGTYASVGNRWQVGHEDEIFAFAL
                     TNAITSTGNGVNLQGLQFCKLIDKSSPLLSNAINQNERLFIEIDLYRINKSGRWERYY
                     YIQLRNASLTAIHVNISDNNLPTECVTVDYDYILCKHLIANTEFDWLAFPAGYNSLFI
                     PPKSPPASNLKPEPLPVVNLPLSSPAVNPVYAKSCLKVKGCTDAGTAEEPAENFGQVA
                     IFVQPVVDDCCGYHHPEANVIGEPAEAQTMLLFPSSVLATQIWGKWSLSGVLSATRGS
                     YIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHGK
                     PQVYGVHTGEGTPYENVRVANMQWNEQTQRYEFTPAHDVDGPLITWTPENPEHGNVPG
                     HTGNDRPPLEQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVY
                     LKEDPRKLPGVVTGHGVPLSPGTRWLDMSVSNNGNGAPIPAHIVDKLRGREFKTFDEF
                     REALWLEVSQEPELIAQFSEINQLRISQGFTPFAPDEGHYIGPKETLKKFQIHHFIAI
                     EYGGGVYDIDNLRIVTPRLHDEIHYRR"
     gene            1914..2198
                     /locus_tag="LSX49_005141"
     CDS             1914..2198
                     /locus_tag="LSX49_005141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL7171387.1"
                     /translation="MFKEKLEDYTEEEFLNFLGGLRSSMKDGKPLKGKELEMYWDSLV
                     DHFIEITQHPSGSDLIFYPKSQGDDKPENILKIVKEWRRSQGLPLFKDSK"
BASE COUNT          672 a          495 c          565 g          644 t
ORIGIN      
        1 taatattgcg agctaagtga aaacgttaag taattgaaat aatttttcat taaaagcgtt
       61 tcttattgat cgagaaataa gttttctatt taatgcaaat aagttaagga taaacgggaa
      121 tgaaataaag tgggcgatat tgtttacctg agaataatcg gtgagaagca gggcgatatt
      181 tcttcaggct gtgggacgta tgcgtcggtt ggtaatcgct ggcaggttgg ccatgaagat
      241 gaaatttttg cctttgcact caccaacgcc attaccagta ctggtaatgg cgttaatcta
      301 caggggctac aattttgcaa actcattgat aaaagctcac cgctactgtc taatgccatc
      361 aatcagaatg agcggttatt tattgaaatc gatttgtatc gtataaataa aagcgggcga
      421 tgggaacggt attattatat tcagctaaga aatgcttcat taactgctat tcatgtaaac
      481 atttctgaca ataatcttcc taccgaatgt gtaactgtcg attatgacta catattatgt
      541 aaacatctca tagccaatac ggaatttgac tggttggcct ttcctgctgg ctataatagc
      601 ttatttattc cgcctaaaag tccacctgcc agtaatctta agcctgaacc gctaccagtt
      661 gttaaccttc cactctcttc accagcggtt aacccggtct atgccaaatc ctgtctgaag
      721 gtgaagggat gtacagatgc cggaacggca gaagaacccg ctgaaaactt cggtcaagta
      781 gcgattttcg ttcagccagt ggttgatgac tgctgtggat accaccatcc cgaggctaac
      841 gttatcgggg aacccgcaga agctcaaacc atgctactgt tcccgagtag tgtgttggcg
      901 actcaaatat ggggaaaatg gtcgctcagt ggcgtactca gtgcaacccg cggctcttac
      961 atcggtgcgt tggcatctgc tctgtatatt ccctctgcgg gtgagggcag tgctcgtgtg
     1021 cctggacgtg atgagttctg gtatgaggaa gaactgcggc agaaagcact agcaggcagt
     1081 accgccacca cccgggtgcg ttttttctgg ggaactgaca ttcacggcaa gcctcaggtg
     1141 tatggtgttc atacgggtga aggtacgccg tatgaaaacg tccgcgtggc gaacatgcag
     1201 tggaacgagc agacgcagcg ttatgaattt acccccgctc acgatgtcga tggccccctg
     1261 attacctgga cgccggaaaa tccggaacat gggaatgttc cgggccatac cggtaacgac
     1321 aggccgccgc tggagcagcc caccattctg gtgacgccga ttccggacgg caccgatacc
     1381 tataccacgc cgccattccc ggttcctgat ccgaaagaat tcaacgatta tattctggtt
     1441 tttccggcgg gatccggtat taagcctatc tatgtttacc tgaaggagga tccgcgaaag
     1501 ctgcctggtg ttgtaacagg gcacggcgtc ccgctttcac caggaactcg ctggctggat
     1561 atgtcggtat ccaataacgg caacggcgca ccaatcccgg cgcatattgt tgataaattg
     1621 cgcggacggg agtttaaaac ctttgatgag tttcgcgagg cgctgtggct ggaggtgagt
     1681 caggaaccgg agttgatagc gcagttttcg gaaattaatc agttacgtat tagtcagggc
     1741 tttacacctt ttgcccccga cgaaggacac tatattggtc ctaaagaaac acttaaaaaa
     1801 tttcagatac atcattttat tgctattgaa tatggcggcg gcgtatacga tattgataat
     1861 ttacgaattg ttacccccag actacacgat gagattcact acaggagata aatatgttta
     1921 aagaaaagct cgaagattat accgaggagg aatttcttaa ttttttaggt ggattgagat
     1981 catctatgaa agatggaaag ccattaaaag gtaaggagct agaaatgtac tgggattcat
     2041 tagtagatca ttttattgaa attacacagc atccgtcagg gagcgatcta attttctacc
     2101 ctaaaagtca aggagatgat aagcctgaaa acatcctgaa aattgtcaaa gaatggcggc
     2161 gttcacaggg gttacccttg tttaaagact ctaaataaag tagataataa aactatatat
     2221 ggaacatcat cgcatctggt taatgcgatg atattaatga cataaaataa taatgtgatt
     2281 gctcttaaaa aacaggtaaa aatactgaag cctcattagg ttattttatc attttcccgc
     2341 ttttaccgat accctttggc tggaggtgag tcagta
//
LOCUS       DAFGPF010000248         2313 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.252, whole genome shotgun sequence.
ACCESSION   DAFGPF010000248 DAFGPF010000000
VERSION     DAFGPF010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.252"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..195
                     /locus_tag="LSX49_005142"
     CDS             <1..195
                     /locus_tag="LSX49_005142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7171388.1"
                     /translation="RLGSQQYYGVNNWQTWNFQCPSGHVLSGINVQDTGSNSADNIAG
                     VYYRPVQKYINGTWYNVASV"
     gene            197..730
                     /locus_tag="LSX49_005143"
     CDS             197..730
                     /locus_tag="LSX49_005143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBL7171389.1"
                     /translation="MMHLKNIKAGNAKTLEQYELTKKHGVIWLYSEDGKNWYEEVKNF
                     QPDTIKIVYDENNIIVAITKDASTLNPEGYSVVEIPDITANRRADDSGKWMFKDGAVI
                     KRVYTEEELRLQTENQKKILLQQAREKTQFWQTQLTLGIITDSDRQQLMNWMRYVQQV
                     ETTDTSVLPVTFPEPPE"
     gene            complement(761..1288)
                     /locus_tag="LSX49_005144"
     CDS             complement(761..1288)
                     /locus_tag="LSX49_005144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBL7171390.1"
                     /translation="MQHLKNITAGNPKTIEQYQLTKKAGVIWLYTEDGKNWYDELKNF
                     QDDTLKIAYDQKGIIRCIEKDVSTLNPDGLSVVELPNITANRRADISGNWKFLDGKVV
                     KREYTKQELQQQAELQKAALLSEAESVIQPLERAVRLNMATDEERTRLESWERYSVMV
                     SRVDTAKPEWPQKPE"
     gene            complement(1304..2272)
                     /locus_tag="LSX49_005145"
     CDS             complement(1304..2272)
                     /locus_tag="LSX49_005145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7171391.1"
                     /translation="MTGELKIGTVNALRIFNDAFGLIFRRSEDFLHFIPTAEGQGENG
                     DIGPLRPFAINLRTGAISVSHGAKIDGGLALGTDNALGGNSITLGDNDTGIKQGGDGV
                     LLFYSNGQLAFGLQPASADFYKRVAYIHQGIIPDGSGAFADQLNNATAPFVQTQFAWN
                     PTPGGLYVPIVKGLSIRNGQGYPGAVSFGYLLTEQYGFPVPCIHMRGDGGNDALWQFN
                     PNDKSFISPGALIAGGVRYNTDGNIFGGCWGSNLNDYLNSSFIRNVRLGGRRSDTLYR
                     GGLCEPGNGHVTTGLQIIGEVDGDDWMVSRPLQKYISGNWYNVEQA"
BASE COUNT          659 a          544 c          482 g          628 t
ORIGIN      
        1 cgacttggtt cacagcaata ttatggagtg aacaactggc aaacatggaa tttccagtgc
       61 ccttcaggtc atgtattgtc tggtattaat gttcaggata cagggtctaa ctctgccgat
      121 aatatagcgg gcgtttatta cagacccgtt caaaagtata taaatggcac ctggtataat
      181 gtagcgagcg tttaatatga tgcacttaaa gaacataaaa gcgggtaatg ctaaaacact
      241 ggaacagtat gagttaacaa agaaacacgg agttatctgg ctttactctg aggacggaaa
      301 aaactggtat gaggaagtga aaaactttca gccagacacc ataaagattg tttacgatga
      361 aaataatatt attgttgcca taaccaaaga tgcctccaca cttaaccctg aaggttatag
      421 cgtcgttgag attcctgata ttaccgccaa ccggcgtgct gacgactcag gtaaatggat
      481 gtttaaagat ggcgcagtca ttaaacgtgt atataccgaa gaagagttgc gcctacagac
      541 ggaaaaccag aaaaaaatat tattacagca ggccagagaa aaaacgcagt tctggcaaac
      601 acagcttact ttggggatta tcactgattc agacagacag caactgatga actggatgcg
      661 atacgtgcaa caggttgaga caactgatac ctcggttctt cctgtaacat tcccggaacc
      721 accagaataa gaaaaggccc gtacgggcct taatttgttg ttattctggt ttctgtggcc
      781 attcaggctt tgcagtatcc acacggctga ccataacgct gtagcgttcc catgattcca
      841 gtcgtgtgcg ttcctcatca gttgccatat tcagtctgac agcacgttcc agcggttgaa
      901 tcacagactc cgcttcggaa agcaaagcgg ctttttgtaa ctctgcctgc tgttgcagtt
      961 cctgttttgt atattcccgc tttactactt taccatccag aaacttccag tttcccgaga
     1021 tatcggcgcg acggttggct gttatattcg gtaactcaac aacacttaac ccgtcagggt
     1081 taagtgttga tacgtctttc tcaatacaac gaataatccc cttctggtca taagctattt
     1141 ttaaagtatc atcctgaaag ttttttaatt cgtcatacca gtttttaccg tcttctgtat
     1201 atagccagat aacgccagct tttttcgtaa gctgatactg ctcaatggtt ttggggtttc
     1261 cggcggtaat atttttcaga tgttgcatat attctcctga tggctatgcc tgttcaacgt
     1321 tataccagtt accagaaatg tatttttgta gtggtcgtga caccatccag tcatctccat
     1381 caacctcacc aataatttgc aatcctgttg tcacatgacc attacctggt tcgcaaagtc
     1441 ctccgcgata taatgtgtca gaacgtctgc ctcccagacg cacatttctg ataaaagaac
     1501 tattcaggta atcatttaag tttgaccccc agcacccacc aaatatattt ccatcggtgt
     1561 tataacggac gccacccgca ataagagcac ccggtgaaat aaaggattta tcgttcgggt
     1621 taaactgcca taaagcatca ttaccgccat cgccacgcat atgaatacat ggaaccggaa
     1681 atccatactg ttctgtcagt aaatacccaa agctgaccgc gccgggatag ccctgtccat
     1741 tgcgaatgga caagccctta actatcggca cgtaaagacc accaggagtg ggattccagg
     1801 caaactgcgt ctgaacaaaa ggcgcggtgg cattattcaa ctggtctgca aatgcgccac
     1861 ttccatcagg aattattccc tgatgaatat atgcaacccg cttataaaaa tcagcagatg
     1921 cgggttgaag cccaaatgcc agttgtccat ttgaatagaa taaaaggaca ccgtcgccgc
     1981 cctgtttaat accagtgtcg ttatctccga gagtaatgga attaccgccc agtgcgttat
     2041 ctgtaccaag cgccagccca ccatcaattt tggccccgtg gctgacagat atagcacctg
     2101 ttctcagatt tatagcgaat ggccttaatg ggccgatatc accgttttcg ccttgtcctt
     2161 cagccgtcgg aatgaaatga agaaaatctt ctgaacgacg gaaaataaga ccgaaggcat
     2221 cattgaaaat tcgcagcgca ttcaccgtgc caattttcag ttctccggtc attttatcgc
     2281 cggaacgctg aacggcgtta ccagccttgt tta
//
LOCUS       DAFGPF010000249         2287 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.253, whole genome shotgun sequence.
ACCESSION   DAFGPF010000249 DAFGPF010000000
VERSION     DAFGPF010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2287
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.253"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(1158..1769)
                     /locus_tag="LSX49_005146"
     CDS             complement(1158..1769)
                     /locus_tag="LSX49_005146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL7171392.1"
                     /translation="MFVYVGSSLVRSYSVPAGKRGNIWTVFKLNPNGEFEDINSVTSA
                     NFNGTTLDVRDLATVIMPATDSSAPASPAMQNSGDTQLARKYNREGEAVYKTGQLEQA
                     IQLFQQATELDGNYGQAFSNLGLAYQKNGNIAEAIWANRKAISLASGVNAATTRANSY
                     YNIAKIYETSGQNAEALQHYQLAYTEKNKPSYEEAIARVKTKM"
BASE COUNT          706 a          473 c          420 g          688 t
ORIGIN      
        1 gaatcattga tgggtttgtt gttaataaat tgtagcaaaa taacacagta aaactaccca
       61 catggaaata tatagataaa aaaccagtat tttatttaac agaaccgcct tatcgacttt
      121 ttataatact agttagttag agtagctact ttgttgccat tttacataac atatttttat
      181 caacgttaat tgattgttgt ctttatgagc aacgtactgt aaatccgtca cttattgttt
      241 cattggtaat aatcacaaga agaaatagat accttaggta tagtcagatg gaacaaggat
      301 tttcaaaata aatttatatg gtattaatat ttcccgatct gtattcaatg attcgctcaa
      361 agattgaaaa tcaagagaaa ttgttatagc agtgatacga gacaacaaaa cggaatgatt
      421 gccagccgtt agaaaacacc ggacactctc gtgtaaaaag ctaccctgtc tatggatata
      481 gcgatatcga ctcatcaagc gtggactgaa tgatattcag ctccatatgg gcggcaacct
      541 ggaggataaa catgatttcg ccgttggaat caaggttgtt ctgcaatatc taccagactg
      601 cttcaattta tctgttttgg aagtgcaata atcttaattt aactatttga agatgatgat
      661 attgtcagat gccagaaatt tagtaatctg gagaaccgtg tctatgatca ctaaatatta
      721 aagtaatagt cgtcagtaac acatcgagtg atataacgta ttgacaccta atcatataaa
      781 aacagatcgt aattaagcag cataagaata tgtcttatta tcattaaaat acattctatt
      841 tccatcatcc ttaagataat aaaacagtga gtgatggata atttcacccc aaaaaaaagc
      901 aagcatataa aattaaaaaa catgactcca ctttcatttt tatgaaatgg catcgtgaag
      961 aggcgccagc caattataaa gatcttgctc ctcaaaaaat gaaacaactc agcctgagat
     1021 aatatttttg accgaagtta acattaaaaa tggttaatag tttgcgcctc tcacacaggt
     1081 ccaggcaact gcgtaacagg caaatcaaat tttcgtaaac agtgggcatc atcagatgcc
     1141 cacaaaatac agctgattta cattttcgtc tttacacgtg caatagcttc ttcataagaa
     1201 ggcttatttt tttccgtata cgccagttga taatgctgca atgcttcagc attctggccc
     1261 gaggtttcat aaattttggc aatgttataa taggagttgg cgcgcgttgt cgccgcattt
     1321 accccactcg ctaacgagat cgctttacga tttgcccaaa ttgcttccgc tatgttgcca
     1381 tttttctgat acgccagacc caggttacta aatgcctgtc cgtaattgcc gtctaattct
     1441 gttgcctgtt ggaagagttg aatggcttgc tcaagttgac cggttttata aacagcttca
     1501 ccttcgcgat tatattttct tgccagttga gtatctccac tgttttgcat cgcaggcgaa
     1561 gccggagctg aagagtccgt cgcaggcatt atcacagtgg ctaaatccct gacgtctaat
     1621 gtggtgccgt taaaattggc gctggtaaca gagttgatat cttcaaactc gccgtttgga
     1681 ttgagtttaa acacggtcca gatgttccct cgttttcctg cagggacact ataactacgt
     1741 accagggagc tccctacata aacaaacact tttgccttac tggcagagag ataattactg
     1801 ttgggcagcc ctttattgct atagtcctgc acggcataga tgtaactttc accaaaatgc
     1861 tttttgctga tagtgacagt ttctggtcca tagctatccg tatcatcaac atccagattg
     1921 gcatcagttc cctctttact atcaaaatag atatgtccgc cagggaagat caaatgcgaa
     1981 tcaagatcaa aaggcttttc gccccagctc aaaactacac gcatgccatc cagattcgtc
     2041 atcaccggac tgatagcata agtcatgcca gcgcacggac atttgaccac cagattggaa
     2101 tacccctctt ttttgacgat taatagagca tctttattat cagcaaatga agtccccaaa
     2161 ctaatgctgc ccgaagtatt tgtgatacca gaaacagatt gtgcaccatt gcgttgcagc
     2221 gtcaccgatg ccccttcaat gcgtttatct ttcactgtcg cacttaaaat atcaatgctt
     2281 acatcgg
//
LOCUS       DAFGPF010000250         2217 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.254, whole genome shotgun sequence.
ACCESSION   DAFGPF010000250 DAFGPF010000000
VERSION     DAFGPF010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2217
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.254"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1197
                     /gene="dsdX"
                     /locus_tag="LSX49_005147"
     CDS             <1..1197
                     /gene="dsdX"
                     /locus_tag="LSX49_005147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
                     /protein_id="HBL7171393.1"
                     /translation="PLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGL
                     TLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCT
                     ALMAVHCVVPPHPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPF
                     KPVPTEFADLKVRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYTLLEFI
                     GNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILK
                     SSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDI
                     SPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTF
                     LLSFII"
     gene            1215..>2217
                     /gene="dsdA"
                     /locus_tag="LSX49_005148"
     CDS             1215..>2217
                     /gene="dsdA"
                     /locus_tag="LSX49_005148"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HBL7171394.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKASQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     "
BASE COUNT          501 a          523 c          570 g          623 t
ORIGIN      
        1 ccactggata tggtaaatgc tattgaaagt ggaattggcg gaacgctggg gttcctcgct
       61 gcggttatcg gccttggcac gatactggga aaaatgatgg aagtatccgg ggccgcagaa
      121 agaattggtc tgacacttca acgctgccgg tggctttcgg ctgatgtcat tatggtgctg
      181 gttggcctga tttgcggcat cacgctgttt gttgaagtgg gcgtcgtgct attgattcct
      241 ctggcttttt caattgccaa aaaaaccaat acctcattgt taaagctggc cattccgctg
      301 tgtaccgcat tgatggctgt gcactgcgtg gttcccccac atccggctgc tttatatgtt
      361 gccaataagc tgggcgcaga tatcggttcg gtgatcgtct acggtttgct ggttgggctg
      421 atggcatcac tgatcggtgg cccacttttc cttaaatttc tggggcaacg actgcccttt
      481 aaacctgtac ccacagagtt tgccgatctc aaagttcgcg atgaaaaaac actaccttca
      541 ttaggcgcaa cgttattcac catactgcta cccattgcgc tgatgttggt taaaacgatt
      601 gccgaattga atatggcgcg tgagagtggt ttgtatacct tgcttgagtt tattggcaac
      661 cctatcactg ccatgtttat cgccgtgttt gtcgcctatt atgtgttggg tatacgtcag
      721 catatgagca tggggacgat gctcacacat acggaaaatg gtttcggttc tattgctaat
      781 attttgctga ttatcggggc cggaggcgca ttcaacgcca ttttaaaaag cagcagtctc
      841 gctgatacgc tggcagttat tctctccaat atgcatatgc acccgattct tctggcctgg
      901 ttggtggcac ttattctgca tgctgcagtg ggctccgcta cggtggcaat gatgggggca
      961 acggcaattg ttgcccccat gctgccgctg tatcccgaca tcagcccgga aattattgcg
     1021 attgctatcg gttccggtgc gattggctgc acgatcgtta cggactcgct tttctggctg
     1081 gtgaagcaat attgcggcgc tacgctcaat gaaacattta aatactatac gacagcgaca
     1141 tttatcgctt cggtcatcgc tctggcgggc acattcctgc tgtcatttat catctaagcg
     1201 caaagagacg tactatggaa aacgctaaaa tgaattcgct catcgcccag tatccgttgg
     1261 taaaggatct ggttgctctt aaagaaacca cttggttcaa tcctggcacg acctcattgg
     1321 ctgaaggttt accttatgtt ggcctgaccg aacaggatgt tcaggacgcc catgcgcgct
     1381 tatctcgttt tgccccctat ctggcaaaag catttcctga aactgctgcc actgggggga
     1441 ttattgaatc agaactggtt gccattccgg ctatgcaaaa acggctggaa aaggaatatc
     1501 agcaaccgat cagcgggcaa ctgttactga aaaaagatag ccatttgcct atttccggct
     1561 ccataaaagc acgcggcggg atttatgaag tcctggcaca tgcagaaaaa ctggctctgg
     1621 aagcagggtt gctgacgctt gaagatgact acagcaaact gctttctccg gagtttaaac
     1681 agttctttag ccaatacagc attgctgtgg gctcaaccgg aaatctgggg ttatcaatcg
     1741 gtattatgag cgcccgcatt ggctttaagg tgacagtgca tatgtctgct gatgcccggg
     1801 catggaaaaa agcgaaactg cgcagccatg gcgttacggt cgtggaatat gagcaagatt
     1861 atggtgttgc tgtcgaggaa ggacgtaaag catcgcagtc tgacccgaac tgtttcttta
     1921 ttgatgacga gaattcccgc acgttgttcc ttgggtattc cgtcgctggc cagcgtctta
     1981 aagcgcaatt tgcccagcaa ggccgtatcg tcgatgctga taaccctcta tttgtctatc
     2041 tgccgtgtgg tgttggcggt ggtcctggtg gcgtcgcatt cggacttaaa ctggcgtttg
     2101 gcgatcatgt tcactgcttt tttgccgaac caacacactc cccgtgtatg ttattaggcg
     2161 tccataccgg attacacgat cagatttctg ttcaggatat tggcatcgac aacctta
//
LOCUS       DAFGPF010000251         2214 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.255, whole genome shotgun sequence.
ACCESSION   DAFGPF010000251 DAFGPF010000000
VERSION     DAFGPF010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2214
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.255"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..587
                     /locus_tag="LSX49_005149"
     CDS             <1..587
                     /locus_tag="LSX49_005149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000635307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL7171395.1"
                     /translation="AENYGIPQRRKRLVLLASRVGKVTLPEITHGKNKIPFKTVRDYI
                     QDFTKLCSGETDPKDPLHRAGTLSPLNLKRIMHTPEGGDRRNWPEELVNKCHKNYDGH
                     TDTYGRMSWDKPAPTLTTKCNSYSNGRFGHPDPTQHRAISIREASRLQTFPLSYVFKG
                     SLNSMAKQIGNAVPCELARLFGLHLIENCTNKDS"
     gene            592..>2214
                     /locus_tag="LSX49_005150"
     CDS             592..>2214
                     /locus_tag="LSX49_005150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL7171396.1"
                     /translation="MAKIRTKARALDMLGRQQIAGIPTALSELFKNAHDAYADNVEVD
                     FFRKENLLILRDDGLGMTTDEFEERWLTIGTSSKLIDDDAINKPAVDSNKAFRPIMGE
                     KGIGRLSIAAIGPQVLVLTRAKRDNELKPLVAAFVNWSLFAIPSLDLDDIEIPIRTII
                     NDECFTKKTLDEMIEQARNNLDSLSHKISKSKVSQINTQLSSFEFDPILWEKKLGGLR
                     LSGDGHGTHFIIMPTEEILIDDISTSDSNKTSEQSSRLEKALLGFTNTMYSDSNPPII
                     ARFRDYLEDGECIDRISESIFFTPQEFNLADHHIEGWFNEFGQFSGTVSVYGEEPIHH
                     VVTWKNNNQLTQCGPFKIKLAYIHGRLRDSRLPMELWAPLKEKTDRYGGLYIYRDGLR
                     ILPYGDSDTDFLKIEKRRTLSASEYFFSYRRLFGAIELTKENNASLVEKAGREGFIEN
                     KPYKQFKEMLENFFIEIARDFFKDDGDMSELFVETKQRRNEEHDLLSKRSKQTKAKKD
                     RLKKDLYDFFDKLDNDYWNIEINKLINKNEEYF"
BASE COUNT          795 a          362 c          432 g          625 t
ORIGIN      
        1 atgctgagaa ctatgggatt ccccaaagaa gaaaaagact cgtgctctta gctagtcgag
       61 taggtaaagt taccctacca gagataaccc atggtaaaaa taaaatccca ttcaaaactg
      121 tacgagatta tatccaggac ttcacaaagt tatgttcagg agaaaccgac cccaaagatc
      181 ctttacatag ggctggaaca ctgagccctc ttaacctaaa aagaattatg cacactccag
      241 aaggagggga tagaagaaat tggccagaag agttagttaa taaatgccat aaaaattatg
      301 atggccacac agatacttat ggaagaatga gttgggataa gcctgcgcct acacttacga
      361 cgaaatgtaa tagttactcc aatggtcgtt ttgggcatcc tgaccccact caacatagag
      421 caattagcat aagagaagca tcaagattac aaacatttcc tttaagctat gtttttaaag
      481 gttcgctgaa ttcaatggca aagcaaatcg gcaatgctgt accttgcgaa ctcgctagac
      541 tatttgggct acatctcata gaaaattgta ctaataagga ttcatagata tatggctaaa
      601 ataagaacaa aggctcgagc tttggacatg cttggcagac aacaaattgc aggtatacct
      661 actgccttga gtgagttatt taaaaatgct catgatgcct atgctgataa tgtcgaagtt
      721 gattttttta ggaaagaaaa tcttcttatc ttgagagatg atggattagg tatgacaacc
      781 gatgaatttg aagagaggtg gttgactatt ggaacctcca gcaaattaat cgacgatgat
      841 gcaattaata aaccagcagt ggatagtaat aaagcctttc gccctatcat gggagagaaa
      901 ggaataggcc gtttatctat cgcagcaatt ggaccacagg tgctggttct tactagggcc
      961 aaaagagaca atgagcttaa gccattagtt gctgcatttg ttaattggag tttatttgct
     1021 ataccatcac ttgatcttga tgatatagaa ataccaatta gaactattat caacgacgaa
     1081 tgcttcacta aaaaaactct tgatgagatg attgagcaag caagaaataa tttagactct
     1141 ttatcacaca aaatatcaaa atcaaaagta tcacaaataa atacacaatt atcatctttt
     1201 gaatttgatc ctattctatg ggaaaaaaaa ttaggtgggc taagactatc tggagatggg
     1261 catggaactc acttcataat aatgcctacc gaagaaatat taatagatga catttccacg
     1321 agcgatagca ataaaacatc agagcagtct tctcgcttag aaaaagcttt attaggtttt
     1381 acaaacacaa tgtacagtga ttcaaaccct cctattatag ctcgttttag agactatctg
     1441 gaagatggtg agtgcattga cagaattagc gaatcaattt tttttacacc gcaagaattc
     1501 aatcttgcag atcaccacat tgaaggatgg ttcaatgaat ttggtcaatt cagtggaact
     1561 gtttctgttt atggtgaaga gccaattcat catgtcgtga cttggaaaaa taataatcaa
     1621 ttaacccaat gcggtccatt taaaataaaa ttagcgtata ttcatggtcg gcttcgtgat
     1681 tcacgcttac ccatggagtt gtgggcccct ctgaaggaga aaacagatag atatggtggt
     1741 ttatatatct atcgagatgg attaagaatt ttgccctatg gagattcaga tacggatttt
     1801 ctaaaaatag aaaagagaag aacgttatcc gcttctgaat attttttctc atatcgacgt
     1861 ttgtttggag caatagaatt aacaaaagaa aacaatgctt cattagttga aaaagctggg
     1921 cgagaaggat tcattgaaaa taagccatat aaacagttta aagaaatgct tgaaaatttc
     1981 ttcatcgaaa tcgcaagaga tttctttaag gacgatggcg atatgtctga attatttgtt
     2041 gagacaaagc aacgtagaaa tgaagaacat gatttgttat ctaaaagatc taaacaaact
     2101 aaagctaaaa aagatagatt aaagaaagat ctgtatgatt tttttgataa gttagataat
     2161 gattactgga atattgaaat aaataagcta atcaataaaa acgaggaata tttc
//
LOCUS       DAFGPF010000252         2142 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.256, whole genome shotgun sequence.
ACCESSION   DAFGPF010000252 DAFGPF010000000
VERSION     DAFGPF010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2142
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.256"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(216..551)
                     /locus_tag="LSX49_005151"
     CDS             complement(216..551)
                     /locus_tag="LSX49_005151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin transporter"
                     /protein_id="HBL7171397.1"
                     /translation="MNRKYYFNNMWWGWVTGGYMLYMSWDYDFKYRLLFWCISLCGMV
                     LYPVAKWYIEDTALKFTRPDFWNSGFFTDTPGKMGLLAVYTGTVFILSLPLSMIYILS
                     VIIKRLSVR"
     gene            680..1027
                     /locus_tag="LSX49_005152"
     CDS             680..1027
                     /locus_tag="LSX49_005152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171398.1"
                     /translation="MTFEQKKARAIALMDSKKMWRSNYAPPLLRILWRLGIRLPPLPF
                     MPFWQVTVLTGGLWGISWGCAMWFIYWGPSGMVAGEAIIISITGGFLSGLLMASFHWW
                     RRKVNRLPPWDDV"
     gene            complement(1047..1616)
                     /locus_tag="LSX49_005153"
     CDS             complement(1047..1616)
                     /locus_tag="LSX49_005153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171399.1"
                     /translation="MTQSRRPSPLQRRVLIVLAALDEKRPGPVLTRDIERVLEQSGEA
                     PVYGPNLRASCRRLEDAGWLRTLRAPNLQLAVELTDAGRAVAQPLLLAEQDRLRADLL
                     PLVPAAGLPAGGTSATDLAVELNGITYQACRGDFVVRLDGSTCLQLWNKEGRVVRREG
                     DPLEVAQWLQACHDAGMEVRVQINESAAP"
     gene            complement(1613..1873)
                     /locus_tag="LSX49_005154"
     CDS             complement(1613..1873)
                     /locus_tag="LSX49_005154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001523449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171400.1"
                     /translation="MDQEMTFSLSYEQLTRFAEKRIRECNLDSHGVTYLCESAKAGAV
                     LIFWHELAINGYTSMNAIKRQEIIDADHQRLRKLIWPEDDWK"
     gene            1975..>2142
                     /locus_tag="LSX49_005155"
     CDS             1975..>2142
                     /locus_tag="LSX49_005155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL7171401.1"
                     /translation="MTKNTRFSPEVRQRAIRMVLESQGEYDSQWAAICSIAPKIGCTP
                     ETLRVWVRQHER"
BASE COUNT          532 a          564 c          515 g          531 t
ORIGIN      
        1 attttcacat taaacacaaa gataaaaaca actatcatta caatatgtgc attatcatat
       61 aatcttacag cgcaagcttc cccgtcatac agacctcgtg atcgagttaa taagactatg
      121 atagaactac aaactaacgg agtagaacgg caacttttag ataattcttg tggcataagt
      181 tctggggtat ttaaataaaa tataagacag gctgtctatc ttacagacag cctttttata
      241 ataacagaaa gaatatatat catacttaac ggaagagata atatgaaaac agtacccgta
      301 taaacagcaa gcaatcccat ttttccaggt gtatcagtaa aaaaaccgct gttccagaaa
      361 tcaggccggg taaatttcag agctgtatct tcaatatacc attttgcaac cggatacaaa
      421 accattccgc agagagaaat acaccagaac agtaatctgt atttaaaatc ataatcccat
      481 gacatataca gcatatatcc ccccgtcacc catccccacc acatattatt aaaataatat
      541 tttctgttca tctgccagtt ttcctttctt ttgcactttt gtcagtgtac tgatgcatga
      601 caacataacc acagcatgat aataataatc aataacaata agctgtgtca cgtttacatc
      661 atggaacgga ggtgctcctg tgacttttga gcagaaaaaa gcccgggcca ttgccctgat
      721 ggacagcaaa aagatgtggc ggagcaatta tgcccctcct cttctgcgta ttctctggcg
      781 gctgggtatc cggcttccgc cattaccctt tatgccgttc tggcaggtca cggtgctgac
      841 ggggggctta tggggcattt cctggggatg tgcaatgtgg tttatctact gggggccgtc
      901 aggaatggtg gcaggtgagg ccattattat aagtatcacg ggggggtttt tgtccggact
      961 gctcatggcc tctttccact ggtggcgcag gaaagttaac cggctgccac catgggatga
     1021 tgtgtaaacc gtgcacaggc gtgttcttac ggagcggcac tttcatttat ctgtacgcga
     1081 acctccattc ctgcatcgtg acaggcctgc agccactgcg ccacttccag cggatcgccc
     1141 tcccggcgta ccaccctgcc ttctttattc cataactgca gacaggtgct gccgtcgaga
     1201 cgcaccacaa aatccccacg gcaggcctga tacgttatgc cgttcagctc caccgccaga
     1261 tcagtggcag aagtgccgcc tgcgggcaga cctgctgccg ggaccagcgg cagcaggtct
     1321 gcccgcaggc ggtcctgttc tgccagcagc agaggctgtg ccacggcccg gccggcgtcc
     1381 gtcagctcca ctgccagctg caggttcgga gcgcgcaggg tacgcagcca gccggcatcc
     1441 tccagacgac ggcaggaggc gcgcaggttt ggcccgtaga ccggggcttc cccgctttgc
     1501 tccagcaccc gttctatgtc ccgcgtcagc acgggtcctg gccgtttttc atcaagggca
     1561 gccagcacaa tcagcactct ccgctgcagt ggcgacggtc ggcggctctg agtcatttcc
     1621 agtcatcctc cggccagatg agctttctga ggcgctgatg gtcggcgtca atgatctcct
     1681 gtctctttat ggcattcatt gaggtatagc catttatggc cagttcatgc cagaagatca
     1741 gcacggctcc ggctttggct gactcgcaga gataagttac gccgtggctg tccagattgc
     1801 attcccggat gcgtttttcc gcaaaccggg tcagttgttc atagctgagt gaaaacgtca
     1861 tttcctgatc catcctgtac gttccatctg ataatgttct gacaggtaaa aatcatatcc
     1921 tgaaccgccc cgggaatcct ggagactaaa ctccctgaga aagaggtaaa caggatgact
     1981 aaaaatactc gtttttcccc cgaagtccgt cagagggcga ttcgtatggt tctggaaagt
     2041 cagggcgaat atgactcaca gtgggcggca atttgttcca ttgccccaaa gattggctgt
     2101 acaccggaga ctctgcgtgt ctgggtacgc cagcatgagc gg
//
LOCUS       DAFGPF010000253         2124 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.257, whole genome shotgun sequence.
ACCESSION   DAFGPF010000253 DAFGPF010000000
VERSION     DAFGPF010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2124
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.257"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            85..642
                     /locus_tag="LSX49_005156"
     CDS             85..642
                     /locus_tag="LSX49_005156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7171402.1"
                     /translation="MAGVGFDGSSDISISAKNVNAFALRQTGNTVNGDTSVGWNWDSG
                     AYNAMIGGASALILHFNINAGSCPAVQFRVNYKNGGISYRSARDGYGFELGWSDFYTT
                     TRKPSAGDVGAYTRTECNSRFITGIRLGGLSSVQTWNGPGWSDRSGYVVTGSVNGNRD
                     ELIDTTQARPIQYCINGTWYNAGSI"
     gene            645..1178
                     /locus_tag="LSX49_005157"
     CDS             645..1178
                     /locus_tag="LSX49_005157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBL7171403.1"
                     /translation="MMHLKNITAGNPKTKEQYQLTKQFNIKWLYSADGKNWYEEQKNF
                     QPDTLKMVYDHNGVIICIEKDVSAINPEGASVVELPDITANRRADISGKWMFKDGVVV
                     KRTYTEEEQRQQAENEKQSLLQLVRDKTQLWDSQLRLGIISDENKQKLTEWMLYAQKV
                     ESTDTSSLPVTFPEQPE"
     gene            complement(1207..1734)
                     /locus_tag="LSX49_005158"
     CDS             complement(1207..1734)
                     /locus_tag="LSX49_005158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001762409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBL7171404.1"
                     /translation="MMHLKNIKAGNAKTLEQYELTKKHGVIWLYSEDGKNWYEEVKNF
                     QPDTIKIVYDENNIIVAITRDASTLNPEGFSVVEVPDITANRRTDDSGKWMFKDGAVV
                     KRIYTADEQQQQAESQKAALLSEAESVIQPLERAVRLNMATDEERTRLEAWERYSVLV
                     NRVDTANPEWPQKPE"
     gene            complement(1736..2113)
                     /locus_tag="LSX49_005159"
     CDS             complement(1736..2113)
                     /locus_tag="LSX49_005159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001470733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL7171405.1"
                     /translation="MGDNDTGFKQNGDGNLDVYANYVHVMRFVPGSIQSNKTINITGR
                     VNPSDYGNFDSRYVKDVRLGSQQYYGVNNWRTWNFQCPSGHVLSGINVQDTGSNSADN
                     IAGVYYRPVQKYINGTWYNVASV"
BASE COUNT          608 a          456 c          471 g          589 t
ORIGIN      
        1 aatcgacaaa cattcagcgg tggcctttct ggggaactgt ccggcaatgc cgctactgca
       61 acaaagctga aaacagcacg aaaaattgct ggagttggtt ttgatggttc tagcgatatt
      121 tcaattagtg ccaaaaatgt caatgcattt gcactccgac aaacaggtaa tactgttaat
      181 ggtgatacat ccgttggatg gaattgggat agtggtgcat ataacgccat gattggtggt
      241 gcatctgcat taattcttca ctttaatata aatgctggta gctgtcctgc cgtacaattc
      301 cgtgtgaatt ataaaaatgg tggcatttcc tacaggtcgg ctcgtgatgg ttatgggttt
      361 gaattaggtt ggtcagattt ctataccacg acacgaaaac cttcagcggg agatgttggt
      421 gcatatacgc ggacagaatg taactcaagg tttattacag gtattcgcct tggcggtctg
      481 tcatctgttc agacatggaa tggtcccggc tggtctgaca ggtcaggtta tgtcgttacg
      541 ggttcagtta acggaaaccg tgatgaatta attgatacaa cacaggcaag gccaattcag
      601 tattgcatta atgggacgtg gtataacgcg gggagtattt aacgatgatg cacttaaaaa
      661 acattactgc tggcaaccct aaaacaaaag agcaatacca gctaacaaag caatttaaca
      721 tcaaatggct ttattcagct gatggaaaaa actggtatga ggaacaaaag aatttccagc
      781 cagacacttt gaaaatggtc tatgaccata acggcgttat tatttgtatt gaaaaggatg
      841 tttcagcaat taatccggaa ggcgcaagcg tcgttgaatt acctgatatt acagcaaatc
      901 gccgggctga tatttcgggg aaatggatgt tcaaagatgg cgtagtggta aagcgaactt
      961 ataccgagga agagcagagg caacaagcgg aaaatgaaaa gcagagcctg ttgcaacttg
     1021 tcagggataa aactcagcta tgggactcac agctacggct gggcatcatt tccgacgaga
     1081 ataaacaaaa attaaccgag tggatgctct atgcgcagaa agtcgaatcc acagacacct
     1141 ccagcctgcc agtaacattt cccgaacaac ctgaatgaga caaggcccga taacgggcct
     1201 taatttttat tcaggctttt gtggccattc aggatttgcc gtatccacac ggttgaccag
     1261 aacactgtag cgttcccatg cttccagtcg tgtgcgttcc tcgtctgttg ccatattcag
     1321 cctgacagcg cgttccagcg gctggatgac tgattcagct tcggaaagca atgcggcctt
     1381 ttgtgattcg gcctgttgtt gctgttcgtc agccgtataa atccgtttaa ccacagctcc
     1441 gtccttaaac atccacttac cggaatcatc ggtccgacga ttggccgtta tatcgggaac
     1501 ctcgacgacg ctaaaacctt cgggattaag cgtggaggca tctctggtga tggcgacaat
     1561 aatattattt tcatcgtaaa caatctttat ggtgtctggc tgaaagtttt tcacttcctc
     1621 ataccagttt tttccgtcct cagagtaaag ccagataact ccgtgtttct ttgttaactc
     1681 atactgttcc agtgttttag cattacccgc ttttatgttc tttaagtgca tcatattaaa
     1741 cgctcgctac attataccag gtgccattta tatacttttg aacgggtctg taataaacac
     1801 ccgctatatt atcggcagag ttagaccctg tatcctgaac attaatacca gacaatacat
     1861 gacctgaagg gcactggaaa ttccatgttc gccagttgtt cactccataa tattgctgtg
     1921 aaccaagtcg aacatctttc acataacggg aatcaaagtt accgtaatcc gagggattaa
     1981 cacgccccgt aatatttatg gtcttattac tttgaatgct tccgggaaca aagcgcataa
     2041 catggacgta attagcataa acatccagat taccatcgcc attttgttta aagcccgtgt
     2101 cattatcacc caatacaatc gaat
//
LOCUS       DAFGPF010000254         2114 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.258, whole genome shotgun sequence.
ACCESSION   DAFGPF010000254 DAFGPF010000000
VERSION     DAFGPF010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2114
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.258"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            67..450
                     /locus_tag="LSX49_005160"
     CDS             67..450
                     /locus_tag="LSX49_005160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171406.1"
                     /translation="MSVLYIQIRRNQITVRDLESKREVSGDAAFSNQRLLIANFFVAE
                     KVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVAGATLMK
                     YRQFHIHAQSVVLSDSAVMAMFKQK"
     gene            complement(514..957)
                     /locus_tag="LSX49_005161"
     CDS             complement(514..957)
                     /locus_tag="LSX49_005161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL7171407.1"
                     /translation="MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRAELEELVH
                     SFLPEAPLWVAVNERDQPIGFMLLSGQHMDALFIDPDVRGCGVGRMLVKHALSMAPEL
                     TTTVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGV"
     gene            1114..2043
                     /gene="metA"
                     /locus_tag="LSX49_005162"
     CDS             1114..2043
                     /gene="metA"
                     /locus_tag="LSX49_005162"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBL7171408.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLDPEVPYNYFPHNDPQNKPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
BASE COUNT          538 a          553 c          472 g          551 t
ORIGIN      
        1 aaaaaccccg gtcaataagg ccggggtttt ttgcatatca attatttgca tgatgaaggg
       61 aatctcatgt cagttctgta tatccaaatt cgtcgtaatc aaattactgt tcgcgatctt
      121 gaaagcaaac gtgaagtgtc aggagatgct gccttcagta accagcgcct gttaatcgcc
      181 aatttctttg ttgcagaaaa agttctgcaa gatcttgttc tgcaactcca cccacgttca
      241 acctggcatt cttttttgcc agcaaaacgt atggatattg ttgtgagcgc gctggaaatg
      301 aatgagggcg gtttgtcaca ggttgaggaa cgcattcttc atgaagtggt cgcaggggca
      361 acgttaatga aatatcgcca gttccacatc catgcgcaat cagtggtact cagtgatagt
      421 gcggtcatgg caatgtttaa gcagaaataa tcatgtcacc attggtgggt acgaaaccta
      481 aagttcagcc caccgggatg agaaaaaaac cgcctacacc cccacatatg ccagattcag
      541 caacggatac ggtttcccca aatcgtccac ctcagagcgt cccgtaacct taaagcccac
      601 cttcttatag aacccaaccg cctgctcatt ttgctcatta acagtggttg tcagttccgg
      661 ggccattgag agcgcatgct tcaccagcat ccggcccacg ccgcagccgc gcacatcagg
      721 atcgataaac agcgcatcca tatgctgccc acttaacaac ataaatccaa tcggctgatc
      781 ccgctcatta accgcgaccc acaacggtgc ttccggcaga aaggaatgca ccagctcttc
      841 cagctcggcc cgatactctg ctgataaaaa atcgtgagtg gcatcgacag aacgacacca
      901 aatcgcaacg agttcctccc cctcctcatg ccgtgagcgt cgaatactaa taaccatttt
      961 ctctcctttt cgtcattctt atattctaac gtagcctttt ccttgaaact ttctcacctt
     1021 caacatgcag gctcgacatt ggtaaatttt ctggttatct tcagctatct ggatgtctaa
     1081 acgtataagc gtatgtagtg aggtaatcag gttatgccga ttcgtgtgcc ggacgagcta
     1141 cccgccgtca atttcttgcg tgaagaaaac gtctttgtga tgacaacttc tcgcgcgtct
     1201 ggtcaggaaa ttcgtccgct aaaggtgctt atccttaacc tgatgccgaa gaagatcgaa
     1261 actgaaaatc agtttctgcg cctgctttca aactcacctt tgcaggtcga tattcagctg
     1321 ttgcgcatcg attcccgtga atcgcgcaac acgcccgcag agcatctgaa taacttctac
     1381 tgtaactttg aagatattca ggaacaaaac tttgacggtc tgatagttac cggcgcgccg
     1441 ctgggcctgg tggagtttaa tgatgtcgct tactggccgc agatcaaaca ggtgctggag
     1501 tggtcgaaag atcacgtcac ctcgacgctg tttgtctgct gggcggtaca ggccgcgcta
     1561 aatatcctct acggcattcc taagcaaact cgcaccgaca aactctctgg cgtttatgag
     1621 catcatattc tccatcctca tgcgcttctg acgcgtggct ttgatgattc attcctggca
     1681 ccgcattcgc gctatgctga ctttccggca gcgttgattc gtgattacac cgatctggaa
     1741 attctggcag agacggaaga aggggatgca tatctgtttg ccagcaaaga taagcgaatt
     1801 gcctttgtga cgggccatcc cgaatatgat gcgcaaacgc tggcgcagga atatttccgc
     1861 gatgtggaag ccggactaga cccggaagta ccgtataact atttcccgca caatgatccg
     1921 caaaacaaac cgcgagcgag ctggcgtagt cacggtaatt tgctgtttac caactggctc
     1981 aactattacg tctaccagat cacgccatat gatctacggc acatgaatcc aacgctggat
     2041 taatcttctg tgatagtcga tcgttaagcg attcagcacc ttacctcagg caccttcggg
     2101 tgcctttttt attt
//
LOCUS       DAFGPF010000255         2070 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.259, whole genome shotgun sequence.
ACCESSION   DAFGPF010000255 DAFGPF010000000
VERSION     DAFGPF010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.259"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            594..947
                     /locus_tag="LSX49_005163"
     CDS             594..947
                     /locus_tag="LSX49_005163"
                     /inference="COORDINATES: protein motif:HMM:NF014678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF192 domain-containing protein"
                     /protein_id="HBL7171409.1"
                     /translation="MVIFEHGQLITLPAAITQADQVKGMSGENHSTGLILAWKTAEPR
                     AVWMKDTPTPLTAAFIGADGVIQSIQDMQPNSDTAHSSLHPTIAIIEMRTEKFKQFRL
                     SKGDKIISSQCFPLK"
     gene            1504..1773
                     /locus_tag="LSX49_005164"
     CDS             1504..1773
                     /locus_tag="LSX49_005164"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CbiX"
                     /protein_id="HBL7171410.1"
                     /translation="MKLTTLLKKHFDIEEITDVDSTVNREVYTIWVYEKGEDCEPLLI
                     LKDAQDFMGVDGWLVGNIYSTLQHGLLLQHEELKTMIRNGEIKSR"
     gene            1862..>2070
                     /locus_tag="LSX49_005165"
     CDS             1862..>2070
                     /locus_tag="LSX49_005165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171411.1"
                     /translation="MSVKDFTPTLEIKFHRRRWRIMVGRSSLASFRSEQDAIDALNKR
                     RSFYEYWAGSAGVQAENTEPVIVHVT"
BASE COUNT          570 a          522 c          500 g          478 t
ORIGIN      
        1 tccgaccccc ttttttttgt acatccgacc ccctaaaaac acgtacatca gaccccccct
       61 aaacctataa ggtgatctcc tgtaggtttc ctgtagtttg accgatagca cttagcctat
      121 aagtttatgc ttttaagaga tcagcctata aaaaaaggcc cgataattta ttcaataaaa
      181 tcagtggata aaaaataaat cgaataattt cagttcagtg tgtacgtgcc aaaatcagca
      241 gcggcagcct ttgcgcttcc tcgcttttgc tgttcgttcc tcgcgttgct gcggtacgcc
      301 tcagcaaaag actgcggcga gcgctgcgat ctcttaggta agcgattagg tttgatgcag
      361 gggggataaa aagagtgagg cccatcaccg gcaagtaatg ggcctctgtc tttcctgcga
      421 aggagcagat tagacgttgt aaaaagtata gacgaaagca gcgtgatatt gaaaggggat
      481 tcatagcgct ttatatttaa tcctcaatat ttaaattttg gtgaattatg aagaaatctc
      541 tattcagtat catcctgctg gctaccacgt accaggcaag cgccgaacct tgcatggtga
      601 tctttgaaca tggtcagtta attacgttac ctgcggctat cacacaggct gaccaggtga
      661 aaggtatgtc aggtgaaaat cacagcaccg gcttaatcct cgcatggaaa acagcagaac
      721 cccgcgcggt ctggatgaaa gatacgccaa ctccacttac agccgcgttc atcggtgctg
      781 atggtgttat ccagagtatt caggatatgc agcccaacag cgacacagcg cattcatcac
      841 tacatcccac gatagcaatc atcgagatga gaacggaaaa atttaaacag ttcaggctat
      901 ccaaaggaga caaaatcata tccagccaat gtttccccct caaataacgc ctcacagccc
      961 catagagctg cttcaacaag aaaagctaac tcaggtatag cccgaaccaa gataacctct
     1021 tacaaagcca tacagagcca ttcaaccaat atcacgccag taatccagtt gtcatcgtgc
     1081 ctgtaggggc gctggccgct gcgcggccaa ccccccaaca cccggataaa tcacgcccgg
     1141 cccgtcgcta cgcgccagcc cgcccgctca accgggccgt tgtgacgggc cactgttccg
     1201 gcggtggtat cgtctgacag cccgccaaaa ccggctttgc agggaggggg tgggcgcgtc
     1261 gcccagctcg atgccgtaag gcccggcaat ttgaccacgc cgcccaggtg gagatcggcg
     1321 cagttgcctt tcatttgtcg gcagcggtgc aaaatttaag tatctttatc gtactatata
     1381 atgataccaa aagttgactt ttagagagaa aaagcctata ctttatttac ggttagcaat
     1441 ggtgctgacc ggcccggaac cagcggcggc aaccgctccg ggaaaactgc gaaggggtga
     1501 aaaatgaaat taaccacgct gctgaaaaaa cattttgata ttgaggaaat taccgatgtg
     1561 gatagcaccg tgaaccggga ggtgtatacc atttgggttt atgaaaaagg cgaagattgc
     1621 gagccgctat taattctcaa agatgcacag gattttatgg gtgtggatgg ctggcttgtc
     1681 gggaatatct attccacgtt gcaacatggc ttattgctac agcatgaaga actgaaaacg
     1741 atgatccgaa acggcgagat taagagccgt taaatctata cgcggtcggc aatagtgccg
     1801 accggcccgg acacagcggc ggcaaccgct ccgggtaaac tgcgaaggta cagaggctac
     1861 tatgtcagta aaagatttca cccctaccct ggaaattaaa ttccatcgtc gccgctggcg
     1921 tatcatggtc gggcgttcaa gcctggcctc tttccgctcc gaacaggacg caattgatgc
     1981 tctcaataaa cgccgctcat tctatgagta ttgggccggt tctgccggtg tacaggcaga
     2041 gaacacagag ccggtgattg tccacgtaac
//
LOCUS       DAFGPF010000256         2040 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.260, whole genome shotgun sequence.
ACCESSION   DAFGPF010000256 DAFGPF010000000
VERSION     DAFGPF010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.260"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            63..311
                     /locus_tag="LSX49_005166"
     CDS             63..311
                     /locus_tag="LSX49_005166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171412.1"
                     /translation="MNNSIPERFIFQCALFKNLEKEVFMTHGYVDSHIIAHALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVLS"
     gene            609..1502
                     /locus_tag="LSX49_005167"
                     /pseudo
     CDS             609..1502
                     /locus_tag="LSX49_005167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415686.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            1634..1852
                     /locus_tag="LSX49_005168"
     CDS             1634..1852
                     /locus_tag="LSX49_005168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171413.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVSHRDQH"
BASE COUNT          545 a          389 c          442 g          664 t
ORIGIN      
        1 gtctgtcgct ttagactata catagcataa ttttattggg tcactattcc tgcgaggctg
       61 acatgaataa ttcaatccca gagagattta tttttcaatg tgctttgttt aaaaacctcg
      121 agaaggaggt gttcatgaca catggatatg ttgatagtca tattattgct catgctttac
      181 ggttgcgttt aaaagatgag accagtgtta ttctttctga tctctatctg caaatcttgc
      241 agtacattga aatgcataag actacactaa cggatatcat tattaatgac agggaatccg
      301 tgctctctta aaacttgagt aaggtttttg aataaacatc agctgtatca ctatgctgat
      361 gcaaagtgag catttcaggc gttatgcttt cttaatatat ccgcaatatc agagggcaaa
      421 caggaatgga gagcgctcgt tttccattct tgacgcctga tatcccgcct aatttgttta
      481 attctgccta cattgttcta aataattaat aggttagatg aagttggaga aaattttatc
      541 ttcggcgtgg atatttgtga tgctctctac catgctatct gtagacccca gcgcgagcga
      601 atgaacgtct ctttagcttc tacagactta tcgataaagg ctttgggatt ttgatattta
      661 ttctgttaat cgcctgcgcc gctgccttcc ttcttgatag gtatttcaat aaaagcgcaa
      721 cgcctgaaga gatcctgcga cgggctataa ataatgggga gatcgtccct ttttaccaac
      781 ctgtggtaaa tggtcgggaa gggacattgc ggggagttga ggtgttagcc cgctggaaac
      841 aacctcacgg tggatatata tcacctgcgg catttattcc acttgctgaa aaatgcggat
      901 taatcgttcc gcttacgcaa agcctgatga atcaggttgc cacccagatg aacgctatcg
      961 cgagtaaact gccggaaggt tttcatattg ggattaattt tagcgcctcg catattgttt
     1021 cgccgacgtt tgtcgacgag tgcttaaatt accgtgacag ttttacccgc cgcgatttaa
     1081 accttgttct ggaagtcacc gagcgtgaac cattaaatgt tgatgaaagt ctggttcagc
     1141 ggttgaacat tctgcatgaa aatggttttg tcatcgcgct ggatgatttc ggtactggtt
     1201 actcagggct ttcttatctg catgacctgc atattgatta tataaaaatt gatcacagtt
     1261 tcgttggccg cgtcaacgca gacccagaat caacccgaat tctggattgt gtattggatc
     1321 tggcgcgtaa actttcgatc agtatcgtcg ctgaaggtgt cgaaacgaaa gaacaacttg
     1381 actatctgaa ccaaaataat attacatttc agcagggtta ttatttctat aaacctgtta
     1441 catacatcga cctggtcaaa attatccttt ctaaaccgaa ggtgaaggtt gtggttgagt
     1501 gaaaattgat cagtaaggcc atggtacggt gtaattatag acagctaatt agctcgttgc
     1561 ctcttgttac tattgttcat tcttttgttt gctataattg tttgaaagtt ttgactggat
     1621 tgccattagt agcatgaaca atagtaataa tctggattat ttcactctct atatcatctt
     1681 ttccattgca tttatgttga tcactctcct ggtcatcctt attgcaaaac ccagcaccgg
     1741 gctgggagaa gtgcttgtga cgataaattt gcttaatgcc cttgtttggc tggcgatcaa
     1801 tctggttaat cgattaaggg aaagactcgt cagccacagg gatcagcact aatctttcag
     1861 tttctcactg tcagtatgcg gctgaatggg ttgctggcag tgaacccctg gatcattgaa
     1921 ggaaaggaat tattgtgcaa atagttgtca accctggtgt tatcacagtt gttttatata
     1981 tcagtgaaat aatttctatg gcaactgttg ataattttga tgtcgaagag ttatttgtta
//
LOCUS       DAFGPF010000257         2024 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.261, whole genome shotgun sequence.
ACCESSION   DAFGPF010000257 DAFGPF010000000
VERSION     DAFGPF010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2024
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.261"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1970
                     /locus_tag="LSX49_005169"
     CDS             <1..1970
                     /locus_tag="LSX49_005169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001773871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HBL7171414.1"
                     /translation="AGSQAGTVRVTAKVQGKTFTLSIKQTATTEPDSEVSAVLTAAPA
                     EQVVGYNINLQLAVKDSQGNAITGDNTLSFYALNQAEGVEFGTVTEKDGVYSATVTSK
                     RAGKITIGVKSDSHDFSGVKKEITFIEDRQQVTFSQFEASQNNALADGKQRNMVTVSL
                     ADRFGNVVPGYAVTLSLPAGITQVGGEHAVSTDENGNAIFALISSTPGSYVITAHAGS
                     QMSTELTVTFASNMTGASLSLTPESSSLISNIPANGKDAAVLDVQLTNTNASVNGQKI
                     QLITSSEGLSVPTNIVTDSTGHVSVPLTTVKAGEYTVTARVTDGSHSVESGSVKLTFV
                     PDVASAELNMSVSKQEIVADGSENATVNIQLVDANNNAFTGEVDLTITPSTGASLTSS
                     NLQLDAHGQATTQFTASKSGQYTIQAEYVLDGKRITASQNIDAVTDVKGAVLEITSSA
                     SSAVVSDTNNLVFTLLLKSKSGEALSGRALNVKTSGPSKYGALVVDKTTVTTDENGQA
                     TVSVHGRTVGSYKLTATLNELGSDVSAVKSFSLYADDANGVLTLTKDPGYETNDGSPV
                     GIYARFVDHFGNPLSGTVEFSAGSEDSPDSQRVKMEPATVTLHWTGNAASEFSTYESG
                     YHWIKAKITNSKNTYEKTIRTYVVKLPEKDS"
BASE COUNT          596 a          390 c          503 g          535 t
ORIGIN      
        1 ctgctggttc gcaggctggt acggtacgtg taactgcaaa agttcaggga aaaacattta
       61 ctctcagtat taagcaaaca gcaacaacag aacctgattc tgaggtcagt gctgttttaa
      121 ccgctgcacc agcagaacag gtagttggtt acaatatcaa tctacaactg gcagtgaagg
      181 attcacaagg aaatgcaatc actggtgata acactctgag cttttatgct cttaaccagg
      241 cagaaggagt cgagtttggg actgtaacgg aaaaagacgg tgtctatagc gcgacagtaa
      301 cttcaaaacg agctggtaag attactatcg gtgttaaatc tgatagtcat gatttctcag
      361 gtgttaagaa agaaatcacc tttattgagg accggcagca ggttacattc tctcagtttg
      421 aagccagcca aaataatgca ttggctgatg gaaaacagag aaatatggta actgtaagcc
      481 ttgcggaccg tttcggcaat gttgttcctg gttatgctgt cacattgtct ttaccagcag
      541 ggataactca agttggtggt gaacatgctg tttcaactga cgaaaatggt aatgctattt
      601 ttgcgttaat aagctccact ccggggtctt acgtgattac agctcatgct ggttctcaga
      661 tgtctactga gttaacagtg acctttgcat caaatatgac cggagcttca ctgtcactga
      721 cgcctgaaag cagtagttta atttccaata ttcctgctaa tggtaaggat gcagcggtat
      781 tagatgtgca gctgacaaat acgaatgcgt cggtcaatgg gcaaaagatt cagctcatca
      841 cctcatctga aggattatct gtaccaacaa atatcgtgac tgattcaaca gggcatgttt
      901 ctgttccgct tacaacggtg aaagctggtg agtacacggt gactgcacgg gtgactgacg
      961 gttcccatag cgtggaatct ggcagcgtta agttaacttt tgtgcccgat gttgcttctg
     1021 cagaactgaa tatgagtgta tcaaaacagg agattgtggc cgatggcagt gaaaacgcaa
     1081 cagtaaacat tcagttggtt gatgcgaata acaatgcgtt tacaggcgag gtggatttaa
     1141 cgattacacc atcgacggga gcatcattga ccagtagtaa tctgcaactg gatgctcatg
     1201 gacaggcaac aacgcagttc actgcatcga aatcaggcca gtacacaatt caggccgagt
     1261 atgttctgga tgggaaacgc ataaccgcaa gccagaatat tgatgccgtg acggatgtga
     1321 agggggctgt gttggagatc acatcatctg catcttcggc tgtagtgagc gataccaaca
     1381 atctggtatt tacgttactg ttgaaaagta agtcaggcga agcattaagt ggtcgagcat
     1441 tgaatgttaa gacatctggg ccgtctaaat atggtgcgtt ggtggttgat aaaaccacag
     1501 taacgactga tgagaacggt caggctacgg taagcgtaca tggtcgaacg gttggttcgt
     1561 ataaattaac ggcgacctta aacgaacttg gcagtgatgt tagcgcggtg aaatcattct
     1621 ccctgtacgc tgatgacgca aatggagtat tgactctaac aaaagatcct ggttatgaga
     1681 caaacgatgg atctccagta ggtatttatg ctcgatttgt cgatcatttt ggaaacccat
     1741 tatctggtac ggttgagttt tctgctggta gtgaagatag tccagactct caacgggtca
     1801 aaatggagcc tgctacagta acgttacact ggacaggtaa tgcagcttcg gaattcagca
     1861 cctatgaaag tggttatcac tggattaagg ccaaaataac gaatagcaaa aatacatatg
     1921 agaaaacaat aaggacttat gttgtaaaac tacctgaaaa ggatagttaa caaaattgaa
     1981 tggggagggc ttagccctcc ctctttttac aggttagcgt ttgg
//
LOCUS       DAFGPF010000258         1997 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.262, whole genome shotgun sequence.
ACCESSION   DAFGPF010000258 DAFGPF010000000
VERSION     DAFGPF010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1997
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.262"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            13..>1997
                     /locus_tag="LSX49_005170"
     CDS             13..>1997
                     /locus_tag="LSX49_005170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl/aryl-sulfatase"
                     /protein_id="HBL7171415.1"
                     /translation="MNNSRLFRLSRIVIAFTAASGMMINTAYATDEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKIYYRANDYKFDINAAAPETV
                     NPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
                     LDLYFQHRPQKPIVAVIYTHSHADHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISE
                     NVLAGNIMSRRALYSYGLLLPHNAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMI
                     IDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFYTLRGAKTRDTSKWT
                     EYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGDMIKLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMG
                     KRYVQALGGSARVINLAQEANKQGDYRWSAELLKQVIAANPGDQVAKNLQANNFEQLG
                     YQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMSVRLDSAKA
                     AGKNISLNFNMNNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
BASE COUNT          521 a          529 c          513 g          434 t
ORIGIN      
        1 atggagattt atatgaataa ctctcggtta ttccgtttga gcaggattgt tattgcgttc
       61 actgccgcca gcggcatgat gataaatacc gcttacgcaa cagatgaggc gaaagccgcc
      121 actcaatata cccaacaggt taatcagaat tacgccaaat cattaccgtt tagcgatcgc
      181 caggattttg acgatgctca gcgtggattt atcgctccgc tgctggatga aggtattctg
      241 cgtgatgcga acggtaaaat ttactaccgc gcgaatgatt acaaatttga tattaatgcc
      301 gctgcgccgg aaaccgtaaa ccccagcctg tggcgtcagt cgcagatcaa cggcatttca
      361 ggcctgttca aagtcaccga taaaatgtat caggtgcgcg gccaggatat ctctaacatt
      421 acgttcgttg agggcgagaa aggcattatt gttattgacc cactggtgac gccacctgcc
      481 gcaaaagccg cacttgacct ttacttccag catcgtccgc aaaaaccgat tgttgccgtt
      541 atctacactc acagccacgc cgaccactac ggcggcgtga aaggtattat ctctgaagcc
      601 gatgttaaat ccggcaaagt tcaggtgatt gctccagctg gctttatgga cgaagccatc
      661 agcgaaaacg tgctggcggg taacatcatg agccgccgtg cgctctactc ttacggtctg
      721 ttactgccgc acaacgcgca aggcaacgtg ggcaacggcc tcggcgtgac gctggcaacg
      781 ggcgacccga gcattattgc accgactaaa actatcgtca gaactggcga gaagatgatt
      841 atcgacggcc tggagtttga cttcctgatg accccaggta gcgaagcgcc agcggaaatg
      901 cacttctata ttccggccct gaaagccctg tgtaccgccg agaatgccac gcataccctg
      961 cacaacttct acaccctgcg cggcgcgaaa acccgcgaca ccagcaagtg gaccgagtat
     1021 ctgaacgaaa cattggatat gtggggtaac gacgcggaag tactgtttat gccgcacacc
     1081 tggccggtct ggggcaataa gcatatcaat gattatattg gtaaatatcg cgatactatc
     1141 aagtacattc acgaccagac cctgcacctg gcgaaccagg gctacaccat gaatgaaatc
     1201 ggcgacatga ttaagctgcc gcctgcgctt gccaataact gggccagccg cggctattac
     1261 ggttctgtca gccacaacgc ccgcgcggta tataacttct atcttggcta ttacgacggt
     1321 aacccggcta acctgcatcc gtatggtcag gtggagatgg gtaaacgtta cgtgcaggcg
     1381 ctgggcggtt ctgcccgcgt catcaacctg gcgcaagaag cgaacaagca aggtgattat
     1441 cgctggtcgg cagaactgct gaaacaggtg attgccgcca acccgggtga ccaggtcgcg
     1501 aagaatctgc aagcgaataa ctttgaacag ctgggctatc aggccgagtc cgccacatgg
     1561 cgcggtttct acctgaccgg cgcgaaagag ctgcgcgaag gggtgcataa gttcagccac
     1621 ggcaccaccg gttccccgga caccattcgt gggatgtcgg tcgaaatgct gttcgacttt
     1681 atgtccgttc gcctcgatag cgcgaaagcc gcgggtaaaa atatcagcct gaacttcaat
     1741 atgaacaacg gcgataacct caacctgacg ctgaacgata gcgtgcttaa ctaccgtaaa
     1801 acactgcaac cgcaagctga cgcctctttc tacatcagcc gtgaagatct gcacgccgtg
     1861 ctgaccggac aggcaaaaat ggctgatctg gtgaaagcga agaaagccaa aattattggc
     1921 aatggtgcga aactggaaga aattatcgcc tgtctggata atttcgattt gtgggtgaat
     1981 atcgtaaccc caaatta
//
LOCUS       DAFGPF010000259         1987 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.263, whole genome shotgun sequence.
ACCESSION   DAFGPF010000259 DAFGPF010000000
VERSION     DAFGPF010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1987
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.263"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(624..1655)
                     /locus_tag="LSX49_005171"
                     /pseudo
     CDS             complement(624..1655)
                     /locus_tag="LSX49_005171"
                     /inference="COORDINATES: protein motif:HMM:TIGR01629.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1648..1923)
                     /locus_tag="LSX49_005172"
     CDS             complement(1648..1923)
                     /locus_tag="LSX49_005172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171416.1"
                     /translation="MPSKRPRATFLLTPELMNAIRSLSDVSGMTMSAIVVQFLEPSIP
                     VMKQLEEVVLEAKKGAAGNGRAIVGSILEGANKTLSELNREFGELDD"
BASE COUNT          658 a          444 c          446 g          439 t
ORIGIN      
        1 aaaaaaaata agcaagaagt gggggtggtg tcttagatgt gagacaaatg tgcagtatta
       61 cagacactgc acagcgattc ggcaacgtgg tcaaacgggg gtcactcatg gtgttgcgga
      121 ttagtcagtg gtcggaaccc cttaaaaccc gtcttacagg tgtgtgtcac ctgctgcgca
      181 cgtaacacac accagcaaga agtgtcttta gtcggggtgt cgtacaaaca ctaaatcgga
      241 acccaaaagg gacccccgat ttagcatttg acgagtcggc ggcggtgaac gctgtcagat
      301 ttcaatctga gagcgcgagg cgtctataga ggggaagtcg gaagggcgca gagggcttag
      361 cttccactga taagagccgc gacccgggca atcaacgtta aaagcaggct gagggccata
      421 aatatcacaa ataacagagg cctcattaaa gtatggataa cgacccatgc cacttaactt
      481 gccagaggta aggccaccaa tagacttaat gacgactaaa gttgtaggag accaagtggt
      541 acgagaaaga taaagaggca aagttaggcc tgtctcataa taaatctcaa aaacattgcg
      601 agcagaatca ccatatctag acattaaata actccatcaa aatacaaatc agtgccaata
      661 gcccaatcag gaacacccat aggcttagcc tctatgatgc gtatgaaggg aacgacatta
      721 tcaggctgct tgtattggac agtggcgata tcaataccca aggcatccat aagagcctta
      781 cggtagcgat agaagctagg acgagagtac atagacctaa tatcgtggcc acacttccaa
      841 agctcataga cagccttata agcaggagat aaaccatcag tcttttcaga agtgatagca
      901 gtaatgtcag ccatgttaat acgtcctata aaatcattta ctatttgcag aggaagcaag
      961 tcatcccatg ccgaaccgga ggaaagaccg cgatgattaa gctcaagcga acgtaaaaca
     1021 acctcacaac gcaaaccacg attagcgtag tcaacgagcg caggaagctg taagaaagct
     1081 gcatgagagt gcttttggaa ctcctcaccc ttagcataga atttcactga gctacggcgc
     1141 gacgatttac caaaatataa cgtagatcct ttagtgacct gaccacgccc acgatgagaa
     1201 agagtggcat tcatctcggc ctgacgaatc caagacagtg cgttagcagt attgccaaca
     1261 tcaaacataa cagtacagtc aacgcggttt aacttgaaat cacccttttc ccaagaacga
     1321 acatcaaaat cagttggatt aagtccaagc tcaggaatag aggttatttt cttcaatacg
     1381 cagcaaagca atggaattaa attatccgtt ccaaaaaggt tatggccttg aaggaattta
     1441 actggattcc catcaaaata aatatgagtc ccgttaccaa agtcattaac agaatgggtt
     1501 ttaagtctta atgatgaatc atggctacca acaacagaaa tagcggtaat agactcccac
     1561 tcaagctcac cggatgagtt gattttagtg attcgcccag aatctaaagg ggtttcatgg
     1621 aaacaaggaa caatagcagt gatccaatca atcatctaac tctccaaatt ccctgttaag
     1681 ctcagagaga gtcttgttag caccctcaag aattgatcca acaatagccc tcccattacc
     1741 agcagcacct ttcttagcct ccaagacaac ttcctctagc tgcttcataa cagggataga
     1801 aggctcaaga aactgaacga cgattgcaga catggtcatg ccagatacat cagaaagaga
     1861 acgaattgcg ttcatcagtt caggggtcag aaggaaagtt gctcgcgggc gcttagaagg
     1921 caaaatggac tcctttctta aatatgagac aaagtgtgca gtggggtaag acccattgta
     1981 accctag
//
LOCUS       DAFGPF010000260         1880 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.264, whole genome shotgun sequence.
ACCESSION   DAFGPF010000260 DAFGPF010000000
VERSION     DAFGPF010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1880
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.264"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..1228)
                     /gene="iutA"
                     /locus_tag="LSX49_005173"
     CDS             complement(<1..1228)
                     /gene="iutA"
                     /locus_tag="LSX49_005173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric aerobactin receptor IutA"
                     /protein_id="HBL7171417.1"
                     /translation="MSKKYTLWALNPLLLTMMAPAVAQQTDDETFVVSANRSNRTVAE
                     MAQTTWVIENAELEQQIQGGKELKDALAQLIPGLDVSSRSRTNYGMNVRGRPLVVLVD
                     GVRLNSSRTDSRQLDSIDPFNIDHIEVISGATSLYGGGSTGGLINIVTKKGQPETMME
                     FEAGTKSGFSSSKDHDERIAGAVSGGNEHISGRLSVAYQKFGGWFDGNGDATLLDNTQ
                     TGLQYSDRLDIMGTGTLNIDESRQLQLITQYYKSQGDDDYGLNLGKGFSAIRGTSTPF
                     VSNGLNSDRIPGTERHLISLQYSDSAFLGQELVGQVYYRDESLRFYPFPTVNANKQVT
                     AFSSSQQDTDQYGMKLTLNSKPMDGWQITWGLDADHERFTSNQMFFDLAQASASGGLN
                     NKKIYTTGRYPSYDITN"
     gene            complement(1316..>1880)
                     /gene="iucD"
                     /locus_tag="LSX49_005174"
     CDS             complement(1316..>1880)
                     /gene="iucD"
                     /locus_tag="LSX49_005174"
                     /EC_number="1.14.13.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NADPH-dependent L-lysine N(6)-monooxygenase"
                     /protein_id="HBL7171418.1"
                     /translation="SGFSGLEEDIRHQLLDEQKMTSDGITADSLLTIYRELYHRFEVL
                     RKPRNIRLLPSRSVTTLESSGPGWKLLMEHHLDQGRESLESDVVIFATGYRSALPQIL
                     PSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFVVNASMQTHGIAEPQLSLMAWRSA
                     RILNRVMGRDLFDLSMPPALIQWRSGT"
BASE COUNT          415 a          496 c          505 g          464 t
ORIGIN      
        1 ggttggtgat gtcatacgac ggatagcgcc cggtggtgta aatcttcttg ttgttcagcc
       61 ctccggaagc gcttgcctga gccaggtcga agaacatctg gttggaggta aagcgctcat
      121 gatcagcatc cagcccccag gtgatttgcc agccgtccat cggtttgctg ttcagagtca
      181 gtttcatgcc gtactggtcg gtgtcctgct gtgacgaaga gaaagccgtc acctgtttgt
      241 tcgcatttac cgtcgggaac gggtagaatc gcaacgactc atcgcggtag taaacctgac
      301 cgaccagctc ctgtcccaga aaagcgctgt cagagtactg caggctgatc aaatgccgct
      361 cagtgccggg aatacggtcg gaattcagcc cgttactgac gaatggcgtg ctggtccctc
      421 tgatggcaga gaagcctttc ccgagattaa gcccgtaatc gtcgtcgccc tggcttttat
      481 agtactgtgt gatcaactga agctgccggg attcatcgat gttcagcgta ccagttccca
      541 tgatgtccag ccgatcggag tactgcaggc cggtctgggt gttatcaagc aaggtggcat
      601 cgccgttacc gtcaaaccag ccgccaaatt tctgatatgc cacggaaaga cgtccggaga
      661 tatgctcatt tccgccggag acagctccgg caatgcgttc atcgtgatct ttactgctgc
      721 taaagccact tttggtgcca gcctcaaact ccatcatggt ttccggctgg ccttttttgg
      781 tcacgatgtt gatcaggcca ccggtactgc cgccgccgta cagggacgtc gcaccggaga
      841 tcacttcaat atggtcgata ttaaaaggat ctatagagtc cagttgtcgg ctgtcggtac
      901 gtgaagagtt gagacgcacg ccgtcaacca gcacgaccag cgggcggcca cgcacattca
      961 taccgtagtt ggtgcggctc cggctgctga cgtcaaggcc agggatcagc tgagccagtg
     1021 cgtctttaag ctctttgccg ccctgaatct gctgttccag ttcggcgttt tcgataaccc
     1081 aggtggtttg cgccatctcc gctacggtgc gattgctgcg gttggcagac accacgaacg
     1141 tttcatcatc ggtttgttga gcgactgctg gcgccatcat ggtaagaagc agtgggttga
     1201 gagcccaaag cgtatacttt ttgcttatca tcattattcc tccatacggg cggaaaaaat
     1261 cagcccaaag atgctgtgta gcgagttaaa gaagcagcct ccggctgcgt tttccctagg
     1321 tgccgctgcg ccactgaatc agggcgggcg gcatactgag atcgaataaa tcacgtccca
     1381 ttacgcgatt aagaatacgt gcagatctcc atgccatcag gctgagctgg ggttcggcga
     1441 tgccatgggt ttgcatactg gcgttgacca cgaagatgtt gttctctttc gggccactcc
     1501 attccagagt gaagtcatca cgcactttaa aggtgttctt atcgtgcatg gtgatcaggg
     1561 gcatcagtga gggaagtatt tgtggcaacg cagaacggta acctgtggcg aaaatcacca
     1621 catcactttc caggctctcc ctgccctgat ccagatgatg ctccatcagc aacttccagc
     1681 caggaccact actttccaga gttgttaccg agcggctggg tagcagacgg atatttcttg
     1741 gttttctcag aacttcaaaa cggtggtaca actcacgata aatggtcagt aaagaatcgg
     1801 cagtgatgcc atccgatgtc attttctgct catccagtaa ctgatggcga atatcttcct
     1861 ccagtccgga gaagcctgaa
//
LOCUS       DAFGPF010000261         1823 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.265, whole genome shotgun sequence.
ACCESSION   DAFGPF010000261 DAFGPF010000000
VERSION     DAFGPF010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1823
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.265"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..306
                     /locus_tag="LSX49_005175"
     CDS             <1..306
                     /locus_tag="LSX49_005175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HBL7171419.1"
                     /translation="CKGKKHYHLMLLVNRDTWCRAGDYRAPGSLAGMIKQAWCSALGV
                     DVGCHATLVHFPAWPAVWLERDDDTGFQQVLERADYLAKEHTKAHCTGERNFGCSRS"
     gene            566..967
                     /locus_tag="LSX49_005176"
     CDS             566..967
                     /locus_tag="LSX49_005176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171420.1"
                     /translation="MYAKSFIALDGNGRLTGARTAQAAPYAHYTCHLCGSALRYHPQY
                     DTELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTHCQTGGFSIPRTTQEEICEF"
     gene            955..1389
                     /locus_tag="LSX49_005177"
     CDS             955..1389
                     /locus_tag="LSX49_005177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HBL7171421.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSRAWGRQEVPSEDARADNPLQRL"
BASE COUNT          428 a          454 c          520 g          421 t
ORIGIN      
        1 tgcaaaggta aaaaacacta tcacctgatg ctgctggtta accgggatac ctggtgtcgt
       61 gccggtgatt accgtgctcc gggatcactg gccgggatga ttaaacaggc gtggtgcagt
      121 gccctgggag tggatgtcgg gtgccatgcc acgctggtgc attttccggc ctggccggcg
      181 gtgtggctgg aacgcgatga tgacactggc tttcagcagg tgctggaacg tgctgactat
      241 ctggcgaagg aacataccaa agctcactgc accggtgagc gcaattttgg ctgtagccgg
      301 agttgagcac gactggcgcg ccaatacccg gcaaaccaaa agtatgggtt gttgtctggc
      361 ggcaacgatg tatccactcg cccactgact gttttttacg tcagtgttcc attgtgtgac
      421 aaccacagtg ctgtaacagc aaccagcctg ctttacccaa actccagtcc agattttaac
      481 tgaaccgcca ttcacaccct gaccacgctg cccgtaccgg gacggctgtt gcctgcgtgt
      541 cgtctggcgg ctgaggaata tgactatgta cgcaaaatcc tttatcgctc ttgatggcaa
      601 cggacgtctg acgggcgccc gtactgcaca ggccgcacct tatgctcact acacctgcca
      661 cttgtgtggc agtgcactca gataccatcc gcaatacgac actgaacttc cctggtttga
      721 acacactgac gacaggctga cagagcacgg tcaacagtgc ccttatgtca ggccggagcg
      781 cagagaaata cagttgatta aacgtctgca gcaattcgta ccggatgcct tacccgtggt
      841 gcgtaaagcc agctggcact gcagacaatg tcaccacgat tattatgggg agcagtactg
      901 cacacactgc cagaccggag gattcagtat tccccggaca actcaggagg aaatatgcga
      961 attctgaact gttatatggc gaatgacagc aaaggccatt ttgttacggc gaaagaagct
     1021 gcgaagcaca accgacagga cgttttgtgc tgtgtgtcct gtggatgccc gttaacactt
     1081 cagcggggca atgacggaca accaccgtgg tttgaacatg accagatgac tgtcgctgaa
     1141 aaaatcctgc tgcgatgtac ctggcttgac ccggcagaga aagaggcccg tcgtttgcat
     1201 ctgcagggca tgacggttcc ggattatacg gtgaaggtga gaaagtggtt ttgtgtgatg
     1261 tgtgacgaag attatgaggg ggaaaagtgc tgcccacgct gcggtaccgg ggtatacagc
     1321 agggcgtggg ggcggcagga ggtgccgtcg gaagatgcca gggctgataa tccgttacag
     1381 aggctgtaat ggttgcctcc ggagcagttt gcggtgatgc ctttcccggg aatggattgc
     1441 cagtgcgggg actgtggagc ttaattccgg tgttggtggc ctttccattg attttatgcc
     1501 aacagccccc tgtgactgac aggctgcctc gtcattccat tcgtatctcc agtaacaggg
     1561 ggttgtattg tattttattg taccggttca ggtgtgcgtt tcccggcgcg tctgcaccgg
     1621 cttaaccaaa ttcaacaggg ataaaatagt ggtaagcgta cagcctgaac cgtctggtca
     1681 gaatctgacg aattagacaa agtggtgtcc accaaataag tagtgggaac caaagtgtca
     1741 gatatgcaga aaaatgtgac tcccggcagg cgaaaaggct gccctaatta tcctcccgaa
     1801 tttaaacagc tgctcgttgc tgc
//
LOCUS       DAFGPF010000262         1725 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.266, whole genome shotgun sequence.
ACCESSION   DAFGPF010000262 DAFGPF010000000
VERSION     DAFGPF010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.266"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1048
                     /locus_tag="LSX49_005178"
     CDS             <1..1048
                     /locus_tag="LSX49_005178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL7171422.1"
                     /translation="LQQSCYEKELTKLYNDAKNALKDVQSKANRLISDNKKKHKSELK
                     NISYEFQSTNLNGKDTAYILDVKRNLESKIENTSNEVINEIRKLTDQIAIISDSTTSE
                     NLSSAQVTEAIETELEHLRDQQANNAELILLGMALSVVHHEFNGNIRAIRSALRELKA
                     WADRNPKLDIIYQKIRTSFDHLDGYLKTFTPLTRRLSRSKTNITGTAILEFIRDVFDD
                     RLEKEGIELFTTSKFVNQEIVTYTSTIYPVFINLIDNAIYWLGKTTGEKRLILDATET
                     GFVIGDTGPGVSTRDRDIIFDMGFTRKTGGRGMGLFISKECLSRDGFTIRLDDYTPEQ
                     GAFFIIEPSEETSE"
     gene            1062..>1725
                     /locus_tag="LSX49_005179"
     CDS             1062..>1725
                     /locus_tag="LSX49_005179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171423.1"
                     /translation="MTSSTDFHKLSEDCVRRFLHSVVAVDDNMSFGAGSDTFPTDEDI
                     NALVDPDDDPTPIITASASPRIESTKSKAKVKNHPFDYQALAEAFAKDGIACCGLLAK
                     SFNVEERDIITASSHKADITILDWDMQSDSGQFAIEIIKSIIVSDINSGGRLRLLSIY
                     TGEHVTAVITKLNNELKKTYRSVIKNDDSIFIEDNYALEQWCIVVISKDVYEKDLPNV
                     LIK"
BASE COUNT          641 a          262 c          310 g          512 t
ORIGIN      
        1 tctacaacaa agttgctatg aaaaagaact aacaaagtta tataatgacg ctaaaaatgc
       61 tttgaaagat gtgcaatcta aagcaaatag gttaatttct gataataaga aaaaacataa
      121 gagtgaacta aaaaacattt cttatgaatt ccaatcaact aatctcaatg gcaaagatac
      181 tgcgtatata ttggatgtaa aaagaaatct agaaagtaaa attgagaata cttcaaacga
      241 agtgattaat gaaataagaa aactaaccga ccagattgca ataattagtg atagtaccac
      301 ttctgaaaat ttatcatcgg ctcaagtaac tgaagcaatc gaaactgaac ttgaacattt
      361 acgagaccaa caagcaaata acgcagagtt aatactactt ggcatggctc tttctgtagt
      421 acatcatgaa tttaatggta atattagggc aattagaagt gcgctaaggg aattaaaagc
      481 atgggctgac agaaatccta agcttgatat tatataccaa aaaatcagaa ctagttttga
      541 tcacttagat ggttatttaa aaacctttac accattgaca agacgtttaa gtcgctctaa
      601 aaccaatata actggaactg ccattttaga atttatcaga gatgtattcg atgatcgtct
      661 tgagaaagaa ggaattgaat tattcactac ctcaaagttt gttaatcaag aaattgtaac
      721 ttacacatca accatttacc ctgtctttat aaatctaatt gataacgcaa tatactggct
      781 tgggaaaaca actggagaaa aaagacttat acttgatgct actgaaacag gatttgttat
      841 tggtgatact ggtcccggtg tttcaactag agatcgagat ataatatttg atatgggatt
      901 tacacgaaaa acaggagggc gtggaatggg attattcatt tccaaagagt gtttatctcg
      961 agatggattt actataagat tggatgatta cactcctgaa cagggtgctt tctttattat
     1021 tgagccatca gaagaaacaa gtgaatagcg gatataaata aatgacaagc tctactgatt
     1081 ttcataaact ttctgaagac tgcgttcgcc gttttttaca ttctgtagtt gctgtagatg
     1141 acaatatgtc ttttggagct ggtagtgata ctttccctac agacgaagat attaatgctt
     1201 tagttgatcc cgacgatgat cctacaccaa taataacagc atcagcatcc ccaaggatag
     1261 aatcaactaa atcaaaagca aaggtaaaaa accatccttt tgattaccaa gctctagcag
     1321 aagctttcgc caaagatggt attgcttgtt gcggattatt agctaagagt tttaatgttg
     1381 aagaaagaga tataattaca gcatcatccc acaaggcaga tataacaata cttgactggg
     1441 atatgcaaag cgatagtggg caatttgcta ttgaaataat aaaatcgata atcgtttcag
     1501 atataaattc tggaggacgt ttacgtcttc tttctattta tactggtgaa catgttactg
     1561 ctgttataac taagttgaac aatgagttaa agaaaacata ccgtagcgta ataaaaaatg
     1621 atgatagtat ttttattgaa gataactatg cactcgaaca atggtgtata gttgttatta
     1681 gtaaagacgt ttatgaaaaa gatcttccaa atgtgttaat aaaaa
//
LOCUS       DAFGPF010000263         1717 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.267, whole genome shotgun sequence.
ACCESSION   DAFGPF010000263 DAFGPF010000000
VERSION     DAFGPF010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1717
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.267"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            182..685
                     /locus_tag="LSX49_005180"
     CDS             182..685
                     /locus_tag="LSX49_005180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HBL7171424.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     AQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(763..1014)
                     /locus_tag="LSX49_005181"
     CDS             complement(763..1014)
                     /locus_tag="LSX49_005181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 domain-containing protein"
                     /protein_id="HBL7171425.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(1129..1215)
                     /gene="azuC"
                     /locus_tag="LSX49_005182"
     CDS             complement(1129..1215)
                     /gene="azuC"
                     /locus_tag="LSX49_005182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HBL7171426.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            1479..>1717
                     /locus_tag="LSX49_005183"
     CDS             1479..>1717
                     /locus_tag="LSX49_005183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171427.1"
                     /translation="MRLLILTLSLITLTGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HARTDRYVSRGIADRACQQAGYTHAIPFGQPVGNC"
BASE COUNT          449 a          405 c          382 g          481 t
ORIGIN      
        1 aacttgatga tttaagcatt ttcttatacc cgttcagacg ttattcttat ttcagatcat
       61 cgtcagaatt gactccacga tcacatttcg gaccggcaga aaggaattat tctgcaaaca
      121 gtaattatgg tgttttgatt tatcttgcac ctctccactt ctggatataa ggatattagg
      181 tatggcaacc gctggaatgc ttctcaaact caactctcaa atgaaccgcg agttttacgc
      241 atccaatctc taccttcacc tgagtaactg gtgttctgaa cagagtctga acggcaccgc
      301 cactttcctt cgcgcccagg cacagagtaa tgtgacccaa atgatgcgca tgtttaactt
      361 tatgaagagt gtcggcgcta cccccatcgt taaagccatt gatgttcccg gtgaaaaact
      421 gaactctctg gaagaactgt tccaaaaaac gatggaagaa tacgagcaac gttcaagcac
      481 gctggcacag ttagccgatg aagcgaaaga actgaatgat gattcaaccg tcaatttcct
      541 gcgcgatctg gaaaaagaac agcagcatga tggcctgtta ctgcaaacca ttcttgatga
      601 agtgcgcagt gcgaaacttg ctggtatgtg tcctgtgcag accgaccaac atgttctgaa
      661 tgtcgtgtcg catcagctac attgatcatc atcggcgcta atgcattgcg ccgatgaagt
      721 ttttgagaaa ccgctgcctc atttttttga agcagcggtt ttttaatggg attcgccctg
      781 tggggtaaac ttgagttcaa tcaacgcgat ggctttttgg attgcccgca tggtgaccgg
      841 gtctgcggcg gcgggatggt tagtaaagtc gatattcttc agctggctgg acattttttc
      901 gcgaacttca acgggcgcga tcacatcgag aacatccaga atttgtttga taaccaactg
      961 gcaagcaacc acatcagaaa ccagttcctg atcggcattc agcggctggg acatcgtaaa
     1021 ctcctgatag cattttgaaa gccgttatag tagcggcttc acatcttcag cgatagtcac
     1081 atccaccgtc atcagaacac aaaaaaacct gccggagcag gttttttgtt atcggaacat
     1141 attgcctggc ggtacgtctt tgaacgtctt gcaatagtta ttgaacatac ttttcaggat
     1201 cttgcgcagt ttcatcgcgg tactccgacc atttgttata caggtgttat tgtctttgcg
     1261 tttataatat gacaaccatc acaaaaatca atctttatgt gatgtaaatc acataaatac
     1321 ccctttaatg ttataaaaat gataatcaaa aaagcagccc tccaatttct gacacataca
     1381 gatggcaaga aatagcgcct gccaggcgtc ttttccggcc attgtcgcag cgctgtaacg
     1441 cgtaaaatac tgctttcttt tactcttctg gctggaccat gagacttctg attctgactc
     1501 tttccttaat aacgctgacg gggtgtacgg ttactcgcca ggcccatgtg agcgaagttg
     1561 acgcggcaac aggtattgtt cggttggttt atgatcaggc ttttttgcag catgcccgta
     1621 ccgatcgtta tgtcagtcgc gggatcgccg atcgcgcatg ccagcaggca ggctataccc
     1681 acgctatccc ctttggtcag ccagtaggca actgtag
//
LOCUS       DAFGPF010000264         1685 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.268, whole genome shotgun sequence.
ACCESSION   DAFGPF010000264 DAFGPF010000000
VERSION     DAFGPF010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.268"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1655
                     /locus_tag="LSX49_005184"
     rRNA            <1..1655
                     /locus_tag="LSX49_005184"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          425 a          373 c          532 g          355 t
ORIGIN      
        1 gaatgctgac ataagtaacg ataaagcggg tgaaaagccc gctcgccgga agaccaaggg
       61 ttcctgtcca acgttaatcg gggcagggtg agtcgacccc taaggcgagg ccgaaaggcg
      121 tagtcgatgg gaaacaggtt aatattcctg tacttggtgt tactgcgaag gggggacgga
      181 gaaggctatg ttggccgggc gacggttgtc ccggtttaag cgtgtaggct ggttttccag
      241 gcaaatccgg aaaatcaagg ctgaggcgtg atgacgaggc actacggtgc tgaagcgaca
      301 aatgccctgc ttccaggaaa agcctctaag catcaggtaa catcaaatcg taccccaaac
      361 cgacacaggt ggtcaggtag agaataccaa ggcgcttgag agaactcggg tgaaggaact
      421 aggcaaaatg gtgccgtaac ttcgggagaa ggcacgctga tatgtaggtg aagcgacttg
      481 ctcgtggagc tgaaatcagt cgaagatacc agctggctgc aactgtttat taaaaacaca
      541 gcactgtgca aacacgaaag tggacgtata cggtgtgacg cctgcccggt gccggaaggt
      601 taattgatgg ggttagcggt aacgcgaagc tcttgatcga agccccggta aacggcggcc
      661 gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acctgcacga
      721 atggcgtaat gatggccagg ctgtctccac ccgagactca gtgaaattga actcgctgtg
      781 aagatgcagt gtacccgcgg caagacggaa agaccccgtg aacctttact atagcttgac
      841 actgaacatt gagccttgat gtgtaggata ggtgggaggc tttgaagtgt ggacgccagt
      901 ctgcatggag ccgaccttga aataccaccc tttaatgttt gatgttctaa cgtgggcccc
      961 ttaccggggt tgcggacagt gtctggtggg tagtttgact ggggcggtct cctcctaaag
     1021 agtaacggag gagcacgaag gttggctaat cctggtcgga catcaggagg ttagtgcaat
     1081 ggcataagcc agcttgactg cgagcgtgac ggcgcgagca ggtgcgaaag caggtcatag
     1141 tgatccggtg gttctgaatg gaagggccat cgctcaacgg ataaaaggta ctccggggat
     1201 aacaggctga taccgcccaa gagttcatat cgacggcggt gtttggcacc tcgatgtcgg
     1261 ctcatcacat cctggggctg aagtaggtcc caagggtatg gctgttcgcc atttaaagtg
     1321 gtacgcgagc tgggtttaga acgtcgtgag acagttcggt ccctatctgc cgtgggcgct
     1381 ggagaactga ggggggctgc tcctagtacg agaggaccgg agtggacgca tcactggtgt
     1441 tcgggttgtc atgccaatgg cactgcccgg tagctaaatg cggaagagat aagtgctgaa
     1501 agcatctaag cacgaaactt gccccgagat gagttctccc tgactccttg agagtcctga
     1561 aggaacgttg aagacgacga cgttgatagg ccgggtgtgt aagcgcagcg atgcgttgag
     1621 ctaaccggta ctaatgaacc gtgaggctta accttacaac gccgaagatg ttttggcgga
     1681 agaga
//
LOCUS       DAFGPF010000265         1676 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.269, whole genome shotgun sequence.
ACCESSION   DAFGPF010000265 DAFGPF010000000
VERSION     DAFGPF010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1676
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.269"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..1675
                     /locus_tag="LSX49_005185"
     CDS             <1..1675
                     /locus_tag="LSX49_005185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2235 domain-containing protein"
                     /protein_id="HBL7171428.1"
                     /translation="LTQNQIIIKENELDYQYITIHYEYIYCKHLTANTEFSYLLTPEN
                     YNRLFPPTLLPVEEKPEIPPEREIILTIGVFFDGTGNNLTNTNLRMSFCQPETYGLDV
                     QDLASFNKQCMSKQGKTGSGVQSYLNYYTNIHWLNKLYHRQLVLDDDVFNIQEKIYIE
                     GIGTENNKADSLVGMGLGNNDTGVIAKTDRAISLLRETLAKIIVDLKDAKLVIKRLQF
                     DVFGFSRGAAAARHFTNRVFERDPVLIKTIATAFQSVEYLGKPSGEVQFLGIFDTVAA
                     IGGLMDGFDPHDGNNFPVKVKLPPGVAKHVFQLTAMNECRYNFCLNSIKESWPELSFP
                     GSHADIGGGYDPLEDEYLFLSRPAIETVLGNVPVEATSAYQKAAQQAELLWRHSTLAP
                     ILPSGVLKIESNIDEIASPDHLGNVRKRVAAAVTFRRTITNDWSKIALRVMYEVAKEA
                     GVVFDAISVADKELKVPSHLKVICEKAISQGKAVLLCTAPMPFSDDELKTIGKYLHCS
                     SNWNTVDYRLKNKVSAEVSAFKTFSFVNRPDENWTRTIYDMQGNKQNGI"
BASE COUNT          523 a          308 c          376 g          469 t
ORIGIN      
        1 gttaactcag aatcagatta taataaaaga aaatgaactc gactatcagt atataacaat
       61 acactacgaa tatatctact gtaagcatct tacagccaat acagaattta gttatttact
      121 cacacctgaa aattataatc gccttttccc accgacgctc ttacctgtcg aggaaaaacc
      181 agaaataccg cctgaacgag aaattatcct caccattggc gtattctttg atggcacagg
      241 aaacaattta accaatacga atttacgtat gagtttttgc caaccagaaa cctatggtct
      301 ggatgtccag gatttggcct cgtttaataa acaatgtatg agcaagcagg gtaaaacggg
      361 atccggagta cagagctatt tgaattacta tacgaatatt cattggttga ataagttgta
      421 tcatcggcaa ttagttttag atgatgatgt atttaatatt caggaaaaaa tatatattga
      481 aggtattggc actgaaaata ataaagcaga ctctctggta ggaatggggc taggaaataa
      541 tgatactggg gtaattgcca aaactgaccg tgcgatatca ctgcttcgtg agacactggc
      601 aaagattatt gttgatttaa aggatgctaa actagtaatt aagcgtctac agtttgacgt
      661 atttggcttt agtcgtgggg cggcagccgc acggcacttt actaatcgcg tatttgaacg
      721 tgatcccgta ctgattaaaa ccattgcgac ggcatttcag tcagttgaat atttaggtaa
      781 accttccggg gaagtgcaat ttttaggtat ttttgacaca gttgcagcca tcggagggct
      841 gatggatggt tttgaccctc atgatggtaa taactttccg gtaaaagtga agttaccgcc
      901 aggtgtggcc aaacatgtat tccagctcac agcaatgaac gaatgtcgct ataacttttg
      961 cctcaacagc ataaaggaaa gctggccaga attaagtttc cctggatcac atgctgatat
     1021 tggtggcggc tatgacccac tggaagatga gtacctgttt ttaagtcgcc cggcgattga
     1081 aacggtactg ggaaatgtgc cggtggaagc gacaagcgct taccaaaaag cagcacagca
     1141 ggcagagtta ttgtggcgcc attcaacgct ggctccgatt ctgccttctg gtgtcctaaa
     1201 aattgaatcc aatattgatg aaatagcgtc gcctgaccac ttaggtaatg tgagaaaacg
     1261 ggtcgctgca gcggtgacat ttcgcagaac gatcaccaat gactggtcaa agattgcgtt
     1321 aagagtaatg tatgaagtcg ctaaagaggc aggggtagta tttgatgcca tttctgttgc
     1381 tgataaggaa ttaaaagttc ccagtcattt aaaggtaata tgtgaaaaag caatttctca
     1441 gggtaaagcc gttctcttgt gtacagcgcc gatgcctttt tctgatgatg agcttaaaac
     1501 cattgggaaa tatttacact gctcttccaa ctggaatacc gtcgattatc gattaaaaaa
     1561 taaggtgtct gctgaagtat cagcgtttaa gacgtttagt tttgttaatc ggccggatga
     1621 aaattggacc agaactatat acgatatgca agggaataaa caaaatggaa tttaat
//
LOCUS       DAFGPF010000266         1626 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.270, whole genome shotgun sequence.
ACCESSION   DAFGPF010000266 DAFGPF010000000
VERSION     DAFGPF010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1626
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.270"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            428..>1626
                     /locus_tag="LSX49_005186"
     CDS             428..>1626
                     /locus_tag="LSX49_005186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171429.1"
                     /translation="MVTRTMQQKYQYDRVLSGELHPFPGIYEAVSEQILLLIFKARQL
                     YQDPEYRPWFEEQHRVLSALRANTELLRIFREQRSAEEPKLTIEDSTSPHPTPSALTD
                     ALNVMCHLYNGFDEGNISLKTWGAMQEVQTTSTFISPGPRTWKTPELAKFVGDDLFNI
                     LTECKAWSSPIPAETRQGYCHQDLSVAHSCTSELLAHLNQYHEIDESAILARVIGITV
                     NGFYKKNNTDLPEWLSPFKEEHKIFRDCPEQNTGDVIRRKEQLLKTGRTEFVNILCRV
                     ANWYEIESIYDEYVRLYANEIIDWFNKTMKYFKPTDFIRYTWKFATVTPDKDTETGHT
                     TAWEKDYCQITIQRDELLRLIHTNTLQDAVIYLCHCLQEKYKKSSQNETEFPGIKPPA
                     SESEINIT"
BASE COUNT          564 a          331 c          330 g          401 t
ORIGIN      
        1 tgacgatttt tgttgactaa aattaggttg ggatatataa ataaatccat gtcaaattca
       61 aacaaggcat ggaggagtcg caggaaggtg aaatatttcc atctaatttg tgataatcat
      121 cacaaaaata agctacaaca agcggaggaa aagacaatct gttgctgaac agacagaagc
      181 aggctacgaa tgatcggaaa atgaagcaaa tacgcttata cagaagacgc agaggtaact
      241 gacggagaca atcacaatca ggagaaaatt atcgtaaata atgtataaaa tctcaggata
      301 taaacaaatg tacacaagct atccacgtaa tcagcggctg gctcaggatt aacgtttcat
      361 ttcagtggac aacatcgatt ctgtctgaca acggaccaat atgtagcaag cagaaacttc
      421 tgacatcatg gtaactcgga caatgcaaca aaagtatcag tatgatcgtg ttttatccgg
      481 cgaactccac ccattccctg gcatatacga ggcggtttcc gaacaaatcc ttttgctcat
      541 ttttaaagca cgtcaactat atcaggatcc agaatatcgc ccctggtttg aagaacagca
      601 cagagtactc tctgcattac gtgccaatac agagctcctg agaatcttta gagaacaaag
      661 aagcgctgaa gaaccaaagc ttactattga agactctacc tccccccacc ccactccttc
      721 tgctcttaca gatgcgctta atgtgatgtg ccatttatac aatggttttg atgaaggaaa
      781 tatcagtctg aaaacctggg gggcgatgca agaggtacag acaacatcaa cctttatcag
      841 cccgggaccg agaacctgga aaacacctga actggcaaag tttgtaggag atgatttatt
      901 taatattctg actgaatgta aggcctggag ttcaccaatt ccagcagaaa cccgacaggg
      961 gtattgccat caggatctgt ctgttgcaca ctcctgcacc tcagagttac tggcacacct
     1021 gaatcaatat catgaaattg atgaatcagc aatacttgcc agagttattg gtataacagt
     1081 taacggattc tacaagaaaa ataatacaga ccttccagaa tggctatccc cctttaaaga
     1141 ggaacataaa atattcagag attgtccgga gcaaaatacc ggggatgtaa tcagacggaa
     1201 agaacaactg ttgaaaacag gacgtacgga attcgtgaat attttgtgtc gggtcgccaa
     1261 ctggtatgaa attgagtcaa tatacgatga atacgtccgt ctttatgcca atgaaatcat
     1321 tgactggttc aacaaaacca tgaagtattt taaaccaaca gattttatcc gatatacatg
     1381 gaaattcgca acagttactc cggataaaga tacagaaacc gggcatacaa ctgcatggga
     1441 aaaggattat tgccagataa ccatacaacg tgatgaactt ctgaggttga ttcacactaa
     1501 tacccttcag gatgctgtaa tttatctttg tcattgtctg caggagaaat acaagaaatc
     1561 atcccagaat gagacagagt ttccaggaat aaaacctccg gcatcagaga gtgaaattaa
     1621 tataac
//
LOCUS       DAFGPF010000267         1588 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.272, whole genome shotgun sequence.
ACCESSION   DAFGPF010000267 DAFGPF010000000
VERSION     DAFGPF010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.272"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..120)
                     /locus_tag="LSX49_005187"
     CDS             complement(<1..120)
                     /locus_tag="LSX49_005187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171430.1"
                     /translation="MEIKVQRPSLWMINTVFLLLPINNHQTNTIKLIFEMCSLD"
     gene            complement(173..577)
                     /locus_tag="LSX49_005188"
     CDS             complement(173..577)
                     /locus_tag="LSX49_005188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HBL7171431.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHIRGKSTFREYCSTLAGAGVFR
                     WVTDVNHNKRSYYAIDNTLLYIEDVENNKPLI"
     gene            complement(798..1529)
                     /gene="bluR"
                     /locus_tag="LSX49_005189"
     CDS             complement(798..1529)
                     /gene="bluR"
                     /locus_tag="LSX49_005189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor BluR"
                     /protein_id="HBL7171432.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTRQDTQDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
BASE COUNT          419 a          352 c          340 g          477 t
ORIGIN      
        1 gtcaagtgaa cacatttcaa atatcaattt gatcgtattg gtctggtgat tatttatggg
       61 aagcaataaa aagacagtat taatcatcca tagggatggt ctctgcactt ttatttccat
      121 tatgctaatg ccttactgaa ttatgaagca tttcttaagc tcccaacttt agctagatta
      181 atggtttatt attttctaca tcttcaatat ataaaagcgt attatcaatg gcgtagtaac
      241 tgcgtttgtt atgattaaca tcagtaaccc accggaaaac gcctgcgcct gccagtgttg
      301 aacagtattc ccgaaatgta gattttccgc gaatatgaag caatgcggcc tcttttattt
      361 tagctgggtt cttggtcgta ctaactttta acaggttcct ggttcctctt aataacaaaa
      421 ccgtgtcatc gtgagtaata attctgatgt tatccgtagc cagataataa atgtaatgtg
      481 caatacggtg atgttttaat tctgaataaa accaggagaa gttttgctct tttctcactt
      541 gctcaaacat cttttgaaaa acaacgacct gatccatcag gataataacc tcttgttagg
      601 tgtgagactg cgtagtgtgc acgatcggtt ttaccacttc aatctggtct gtcctttggc
      661 tgtgatatgt acaaagtgtc aaagggggat tacctgaatt ctcccggtga gcattttgca
      721 acggaccagc tccgctacaa acgctgttgt gggttcagat tataacattc tgtctaaggg
      781 gcgggataaa ggtgaattta gggggcatga aagatgactt tataaccttg ctcaccccag
      841 tgttgtaaaa gttcgttttg ccttctcgtt ggtgccatgc ctgtccagac aatcaatgtt
      901 tgcgttggga acagttccgg gcgcggcgat tcaatgggat cagcaagaac agaaatgtgc
      961 catcctgaca atgataaacg ccatgcttcc agccacaatc gtgctctctc ttcaacattc
     1021 cacgccatca gaatggcctc tttaccgggc ttacggcgca tttcgaaaag tgaggccgct
     1081 gcgtattcaa ttaatgcgcc gtcaaacata ctgctcataa tgcgggaggt gttgtgatca
     1141 agcacgagac gctggcgaac aggaaggtaa acatgattaa tcaattgatc tactgggtac
     1201 tctcgaccca gtgaaataat tcgcgcgcgt agtttggctg gattagccat acgaagaatt
     1261 gacatcatct cttcttgcag gcggctccag tcatcttgcg tatcctggcg ggtagtttcc
     1321 agtaatgctt taactttgcc tacaggaacg ccattactta tccaacgctt gatctcttcg
     1381 atgcgttgta tgtcttcttc atcaaagagt cggtgtccgc cttcactgcg ttgtggtttt
     1441 aacaaaccgt agcggcgttg ccaggcccgg agagtgacag gattaatccc gcaacgttca
     1501 gcaacatcac caatgctgta ataagccaca attcctcctt gcggtcataa atctccgtcg
     1561 cctctacacg acccaataat actttgta
//
LOCUS       DAFGPF010000268         1544 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.273, whole genome shotgun sequence.
ACCESSION   DAFGPF010000268 DAFGPF010000000
VERSION     DAFGPF010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1544
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.273"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(98..238)
                     /locus_tag="LSX49_005190"
     CDS             complement(98..238)
                     /locus_tag="LSX49_005190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171433.1"
                     /translation="MPVGALAAARPTPQHPDKSRPARRYAPARPLNRAVVTGHCSGGG
                     IV"
     gene            complement(1102..1524)
                     /locus_tag="LSX49_005191"
     CDS             complement(1102..1524)
                     /locus_tag="LSX49_005191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171434.1"
                     /translation="MSAYVVSDKAISTIVKTLVLTGTLQPVEAVSFGQMMLNLNTHSV
                     NVRYQESSPAHAFEYSEPELNINDPKTQIQVIVCIDEYEYQSCEFAEYYETMVHTVLK
                     AIKSALHEAYTETLPNPARWKAKKSYELPGYSEAEWSL"
BASE COUNT          347 a          405 c          504 g          288 t
ORIGIN      
        1 tccccggagc cgaacggggc agggcgttac gtcgccggtg acgccgacca gggcgaagcg
       61 cccaccccct ccctgcaaag ccggttttgc cgggctgtca gacgataccg ccgccggaac
      121 agtggcccgt cacaacggcc cggttgagcg ggcgggctgg cgcgtagcga cgggccgggc
      181 gcgatttatc cgggtgttgg ggggttggtc gcgcagcggc cagcgcccct acaggcacga
      241 cagcgccgta actggcagag gatggcgaag ccaccccgaa ggggcggggc cgccggaggc
      301 ggggcaagtc cggcgcaggg cgtgggggcc aagcggagcg cggagggcga agcccggagg
      361 cgttagggat tgaagcccga aggggcgaga cagcttgcct ggctcgatgc gcagcacgaa
      421 agcccgcccc gcagggaacg ccctgattaa ccggcggccg cagcggggcc aatcacggcg
      481 agaaccaaaa ataaccctgc tgtgaaatcc acggatcgta cagcagggta agccagggga
      541 gcaggggaaa ggggcggctt gccgcccctt tccgttactt cttcttgctt ttcaggactt
      601 ttatcaggcc ggtgatggct gtgatgaggg ctgcgatagc gaggataacc ggcgggagga
      661 gttggagaat ttcggccata aagcacctgt agggtagttg gagggtttgt cgtttccgac
      721 aaccggtgtg taacactggc gcaaggggtg gggtcaatag cgcgaagcgg cgaagcgaac
      781 tattgacgcc acaccgcgct agtgtggaat accggtaatg gaggaacggc agaccatcca
      841 acggaacggg gagctgtgga ggacagttcg cctcccgccg gttatcctcg cggcccggag
      901 ttggcaccgg ctgaaaaagc caagcgaagc gcggagggcg aagcccggag gcgttaggga
      961 ttgaagcccg aaggggcgag acagcttgcc tggctcgatg cgtagcacga aagcccggcc
     1021 cgcagggaac gccagagatc accggcgcaa aaaaaggggc aacgccccta caggtagagc
     1081 ggggggctta cccccgcgcg atcataaact ccattcagct tctgagtagc ccggcagttc
     1141 ataggatttt ttagctttcc accgggcggg attaggcaat gtttcagtat aagcctcatg
     1201 taacgctgat tttatagctt tgaggactgt atgcaccatc gtttcatagt attcggcaaa
     1261 ctcgcaggac tgatattcat actcatcaat gcagacaatc acctgaattt gtgtttttgg
     1321 gtcgttaata tttagctccg gttcactgta ttcaaaagcg tgcgccgggc tactttcttg
     1381 atagcgaaca ttaacagaat gggtattcag atttagcatc atctgaccaa atgaaacagc
     1441 ctcgacaggc tgaagtgtgc cggtcagtac cagagtttta acaatagtag aaatggcttt
     1501 atcagatact acgtatgcgc tcataattta ttccttcgca ggtt
//
LOCUS       DAFGPF010000269         1476 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.274, whole genome shotgun sequence.
ACCESSION   DAFGPF010000269 DAFGPF010000000
VERSION     DAFGPF010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.274"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1..555
                     /locus_tag="LSX49_005192"
                     /pseudo
     CDS             1..555
                     /locus_tag="LSX49_005192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012016515.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="metal ABC transporter permease"
BASE COUNT          468 a          299 c          226 g          483 t
ORIGIN      
        1 cattattatc agtttttctg gtattaaaag gctgggcgct aataggagat gcaatgagcc
       61 acgcaatgtt tcctggcata gttctagtct ggattatagg tatgccgctg ggaattggtg
      121 catttattgt aggactgtct tgtgcaattg caactggcta tctgaaagat aatagcatta
      181 taaagaaaga taccattata ggtatcgttt tttcaggaat ttttgtcttg actatcaaca
      241 ggcacaagtc agcggattac agatatcatt attacattac ggtttactct gcatggtatc
      301 gcctaccatt tttgccacat taaaagcagt cggaattatt ctgtctatat actattaata
      361 gctccagggt ctattgctgt cctcatcatg catcgctttc ataaggcatt acttatcgcc
      421 gtaacgatat caataacaat atcaggcgta tggttattat attttctcaa cagagcccca
      481 gcgccgacaa tcgtcctctt atttgctgta gcatttcttt tcgcgctgat aataatcaat
      541 tttcggaaac aataatctca acagtagaat aaagaggcaa atcaatcatt acatatataa
      601 gatggtgcta atattgtacc gcctttaaat tgaactttat cctttcaccc ttacacaatt
      661 taaggaatgc agatgactat tttatcagcc cccagccttt ttcctggtaa tcgaaaactt
      721 gaaaatcatt aactctaaga agttctgcca aatcgttgaa attactttaa attagactcg
      781 aacaaatcaa tccctgatgg ggcttttact tatccattta atcgggtaga tatcgacctc
      841 catctgcccg cctcagattc gtacctggtg gaggtctttt ttcgttacct ctttccccct
      901 ttagttcagt ataaaatcat caaactaatg ctgttcacac tatttacctc cagcattcta
      961 tataaataat agaaataaaa accccaatac atagtgcatt ggcatgacca aacatcaatg
     1021 ccattatact cgcctctgtt aaatactcgc tagttaatat gataggcacg catgatataa
     1081 caatccatat gctaatacat aaatacatca gtatttttct catagtcagt ccctgtgatt
     1141 aacaatcaag gcatagttaa gcatatttca cattcaaacg taaacattat taataacatt
     1201 atatcaatcg aactgacatc acgattcaag ccctcttcaa actgaaggtt agagcagcgt
     1261 agaacatttc aaaacaatac actaaaaaaa tacctgaaca aaaaacttaa ttctttttta
     1321 ttgtgaactt tagtgatttt gtcatgcaac tctttattac atttaggcct gtattatttc
     1381 atggcaacgc agatacagga ccatttcttg tgctatggat aagtaataag ctagttacat
     1441 cttattaaga gaaccatttt cacatatcaa gatatc
//
LOCUS       DAFGPF010000270         1472 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.275, whole genome shotgun sequence.
ACCESSION   DAFGPF010000270 DAFGPF010000000
VERSION     DAFGPF010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1472
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.275"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..752
                     /locus_tag="LSX49_005193"
     CDS             <1..752
                     /locus_tag="LSX49_005193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide 1,3-galactosyltransferase"
                     /protein_id="HBL7171435.1"
                     /translation="LINGDRLRSLPSTKNWTHAIYFRFVIADYFISKVAKVLYLDADI
                     ICQGTIEPLIKFSFPDDKVAMVVTEGQADWWEKRAHSLGVAGISKGYFNSGFLLINTA
                     KWAAQQVSARAIAMLNEPEVIKKITHPDQDVLNMLLADKLIFADIKYNTQFSLNYQLK
                     ESFINPVTNNTIFIHYIGPTKPWHDWAWDYPVSQAFMEAKNASPWKNTALLKPNNSNQ
                     LRYSAKHMLKKHRYLKGFSNYLFYFIEKIKH"
     gene            792..>1472
                     /gene="rfaJ"
                     /locus_tag="LSX49_005194"
     CDS             792..>1472
                     /gene="rfaJ"
                     /locus_tag="LSX49_005194"
                     /EC_number="2.4.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase RfaJ"
                     /protein_id="HBL7171436.1"
                     /translation="MDSFPAIEIDKVKAWDFRLANINTSECLNVAYGVDANYLDGVGV
                     SITSIVLNNRHINLDFYIIADVYNDAFFQKVAKLAEQYQLRITLYRINTDKLQCLPCT
                     QVWSRAMYFRLFAFQLLGLTLDRLLYLDADVVCKGDISQLLHLDLNGAVAAVVKDVDP
                     MQEKAASRLSDPELLGQYFNSGVVYLDLKKWANAKLTEKALSILMSKDNVYKYPDQDV
                     MNVLLKGMT"
BASE COUNT          469 a          245 c          288 g          470 t
ORIGIN      
        1 atctgattaa tggtgatcga ctgcgctcat tgcctagcac aaagaactgg actcatgcaa
       61 tatattttcg ttttgttatt gctgattact ttattagtaa ggtggctaaa gtcctttatc
      121 tggatgcaga tatcatttgt caggggacta ttgagccact aattaaattc tcatttcctg
      181 acgataaagt cgcaatggtt gttacagaag ggcaagctga ctggtgggaa aaacgcgccc
      241 attcgttagg tgttgcggga atttctaaag gttactttaa ctccggtttt ttattgatta
      301 atactgccaa atgggcagct cagcaggttt ctgcacgagc cattgcaatg ctaaatgagc
      361 cagaagtaat caaaaaaata acacatcctg atcaggatgt attaaatatg ttgctggcag
      421 ataaacttat tttcgctgat attaaatata acacccagtt tagcttaaat tatcaactaa
      481 aagaaagctt tataaaccca gtaaccaaca atactatttt tatccattat atcgggccaa
      541 ccaagccctg gcatgattgg gcctgggatt atcctgtatc acaagccttt atggaggcaa
      601 aaaatgcttc gccatggaag aatacagcgt tgctgaaacc gaacaatagc aatcaattaa
      661 gatatagcgc aaaacatatg cttaaaaaac atagatatct aaaaggattt agcaactatc
      721 ttttttattt tattgaaaag ataaagcatt aaaactggga aacaataaag taatgatata
      781 agggtagcat tgtggactca tttcctgcca tagagataga taaagttaaa gcctgggatt
      841 ttcggctggc taatataaat acttctgaat gtttaaatgt tgcctatggt gtcgatgcta
      901 attatcttga tggtgtaggt gtttccatta catcaattgt cctaaataat cgacatatta
      961 atcttgattt ttatattatt gctgatgttt ataatgatgc ttttttccaa aaagttgcaa
     1021 agcttgcaga gcaataccaa ttaagaatca cattatatag aattaacact gataagctcc
     1081 agtgcttgcc ttgtacacag gtctggtcaa gagcaatgta cttccgttta tttgcatttc
     1141 aattattggg tttaacactt gatcgtttgc tttatcttga tgcagatgtt gtttgtaaag
     1201 gcgatattag ccaactattg catctggatt taaacggcgc ggttgctgct gttgttaaag
     1261 atgttgaccc aatgcaggaa aaggcggcat ccaggttgtc tgatccagaa ttactcgggc
     1321 agtactttaa ttccggtgtc gtttatttag atttaaaaaa atgggctaac gcaaaactaa
     1381 cagaaaaagc gttgtctatt cttatgagta aagataatgt gtataaatac cctgatcaag
     1441 atgttatgaa tgtcttactg aaagggatga ca
//
LOCUS       DAFGPF010000271         1438 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.276, whole genome shotgun sequence.
ACCESSION   DAFGPF010000271 DAFGPF010000000
VERSION     DAFGPF010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.276"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..451
                     /locus_tag="LSX49_005195"
     CDS             <1..451
                     /locus_tag="LSX49_005195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002431274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylneuraminic acid channel protein"
                     /protein_id="HBL7171437.1"
                     /translation="DKWALIPGIQTQWMSAGSQYNPYLKISYQATPDLNLALRYRYDW
                     KAFRQTDLDGNRARNDQHQFDGYVTYKINDSWLFAWQTTVYTKVNNFKYGNHKKTATE
                     NAFVLQYKMSPVFTPYIEYDYLDKQGVYKGKDNKHENSYRVGVLINF"
     gene            464..>1438
                     /locus_tag="LSX49_005196"
     CDS             464..>1438
                     /locus_tag="LSX49_005196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HBL7171438.1"
                     /translation="MKVKNFIYLPFCLFIGTSVAGALPEIPEPFKYGVGGIENGKIYI
                     GLGSLGNNWYMIDTNQSEKKWTKIAQWPTVPREQATATIIDGKIYVFGGIGKDKSGVI
                     TLQKDVYSYDIAKDKWEKLMTRPPVSLAGHVSFIHNGHAVSTGGVNENIFNGYFSDVE
                     LSKGNSALTEKVNRDYFSKPADDYFLNNHIISYDPSKNQWKNLGTTPFPGTAGSSVIF
                     AEQQIYILGGERKPGLRSVRSWTGELSHDRIKWSELPPVASPEGVSGAYASVIDGNIF
                     LAGGAYFPGAAEKYSNGEYWSHKGLDKAYSKEIYQLIKNDWKKVGSLPE"
BASE COUNT          467 a          234 c          333 g          404 t
ORIGIN      
        1 tgacaaatgg gctctaatcc cagggattca gacacaatgg atgtcagcag gaagtcagta
       61 taacccttat ctgaaaattt cgtatcaggc aacgccagat cttaatctgg ccttacgcta
      121 tcgctatgac tggaaagctt tccgacagac ggatttagat ggcaacaggg cgcgtaatga
      181 tcagcatcag tttgatggtt atgtgacata caaaattaat gattcatggt tgtttgcatg
      241 gcagaccacg gtatatacga aggttaataa tttcaaatat gggaatcata aaaaaacagc
      301 aactgaaaat gcatttgttc tgcaatataa aatgtcaccg gtgttcaccc catatataga
      361 atatgattac ttggataaac aaggggtgta taaggggaaa gataataaac atgaaaatag
      421 ttaccgtgtc ggtgttctga ttaattttta aaaggtgatt acaatgaaag tgaaaaactt
      481 tatatatctt cccttctgct tgtttattgg aacgtcggta gccggagctt taccggaaat
      541 tcctgaacca tttaaatatg gtgtaggagg gatcgagaat ggtaaaatat atataggact
      601 aggaagtctg ggaaataact ggtatatgat agatacaaac cagagtgaaa aaaaatggac
      661 taagatagcg caatggccga cagttcccag agagcaggca acagctacta ttattgatgg
      721 taagatctat gtatttggag gaattggaaa agataaaagt ggagtcataa ccttacaaaa
      781 agatgtctat tcctatgata ttgctaaaga taaatgggaa aaattgatga cccgtccccc
      841 tgtatctctt gccggtcatg tttcttttat ccataatggt catgcggtat ctactggtgg
      901 tgtaaatgag aatattttta atggatactt ttcagatgtc gagttatcaa aagggaattc
      961 cgcgctgaca gagaaagtca acagggatta ttttagtaaa cctgctgatg attatttttt
     1021 aaataatcat ataatttctt atgacccgtc aaaaaaccag tggaagaacc tgggaacgac
     1081 tccatttccg ggaactgctg gttcatcggt gatttttgca gaacagcaaa tttatatact
     1141 gggaggggag agaaaaccgg ggcttcgttc tgttagatcc tggacggggg agctttcgca
     1201 tgatcgaatt aaatggtctg aacttccacc agtagcttca cccgaggggg tgtcaggagc
     1261 atatgcctct gttattgatg gaaatatctt tctggccggt ggtgcatatt tcccgggggc
     1321 ggcagaaaag tatagcaatg gtgaatactg gtctcataaa ggactggata aagcctattc
     1381 aaaagagata tatcagctaa taaaaaatga ctggaaaaaa gttggttctt tgccggaa
//
LOCUS       DAFGPF010000272         1437 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.277, whole genome shotgun sequence.
ACCESSION   DAFGPF010000272 DAFGPF010000000
VERSION     DAFGPF010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1437
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.277"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..522
                     /locus_tag="LSX49_005197"
     CDS             <1..522
                     /locus_tag="LSX49_005197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBL7171439.1"
                     /translation="SISDKSVVANKDLTISVVDDKRRIYGVEGAVDYLIPDTDWSTGV
                     NFNVLKTESKVNGTWQKYDVKTASPSKATAYIGWAPDPWSLRVQSTTSFDVSDAQGYK
                     VDGYTTVDLLGSYQLPVGTLSFSIENLFDRDYTTVWGQRAPLYYSPGYGPASLYDYKG
                     RGRTFGLNYSVLF"
     gene            complement(1073..1216)
                     /locus_tag="LSX49_005198"
     CDS             complement(1073..1216)
                     /locus_tag="LSX49_005198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001421454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171440.1"
                     /translation="MEHRSVIHDELAIDHDAILQCAEEVLHRCVIQTVSFVRHILCYS
                     MGL"
BASE COUNT          400 a          333 c          343 g          361 t
ORIGIN      
        1 tcgatttctg ataagagcgt ggtggcgaat aaagatctga ccatcagcgt ggtggacgac
       61 aaacgccgta tttacggcgt ggaaggtgcg gtggactacc tgattcctga tactgactgg
      121 agtaccggag tgaacttcaa cgtgctgaaa actgagtcga aagtgaacgg tacctggcag
      181 aaatacgatg tgaagacagc aagcccatca aaagcgacag cctacattgg ctgggcaccg
      241 gacccgtgga gtctgcgcgt gcagagcacc acctcctttg acgtgagcga cgcgcagggc
      301 tacaaggtcg atggctatac caccgtggat ctgctcggca gttatcagct tccggtgggt
      361 acactcagct tcagcattga aaacctcttc gaccgtgact acaccactgt ctgggggcag
      421 cgtgcaccac tgtactacag cccgggttac ggcccagcgt cactgtacga ctacaaaggc
      481 aggggccgaa cctttggtct gaactactct gtgctgttct gacggggatg cttttgcaac
      541 aagggtatgc tgtaaacaac atggtccttg gtggccatgt tgtttacagc cagtataata
      601 tacagcctta acaagatatt ccgtctccgg aatggactgt tcaccactga ataacattat
      661 gtctgtttta tggatctttg actgaaattt atcgcatatc ctcatttcat tgtccgtctg
      721 aaaactaacc ttacaagtaa gcgtcgtctc agcaccgtct ggcagatcct gaaattcctg
      781 ggaggatgat ctgcgcccaa tatcctgagc cggaactttg ctgcaatgaa ggccaacgaa
      841 aaatggggga gtatgttata gagtacttgc tacagggtaa aaagaggtac ctgtcgctgg
      901 ttctccgttc agtttaaccg ggagattttc tcctgcgcct gtcataaagt ccggtaatgg
      961 agattgttaa tacgatggtg cacgatgcat tgtcagtgcc cggcccggag gatgccccgt
     1021 agctacatac ggatcagggt tggcaatatc gaatggcagg ctataggcaa agttaaagcc
     1081 ccatggagta gcacaaaata tgccgcacaa aggaaacggt ctgaataacg cagcgatgga
     1141 gaacttcttc ggcacactgc aaaatcgcat cgtggtcgat cgctaattcg tcgtgaatca
     1201 ctgaacgatg ttccatgcga acagatattc gatcatatcg aaatattaaa cattacccct
     1261 ccccacattg ggcaaaaaaa aacaaaaaac gatcaattaa cgatcaatta gtattgattc
     1321 acataatctc tcatcattaa tgagaacatt gtcacatatt tacaatatag aactgttact
     1381 tttagcaagc tgttagtaac caaccgttac taataatttt aattcttaat actttgt
//
LOCUS       DAFGPF010000273         1373 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.279, whole genome shotgun sequence.
ACCESSION   DAFGPF010000273 DAFGPF010000000
VERSION     DAFGPF010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1373
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.279"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1..>1373
                     /locus_tag="LSX49_005199"
     CDS             1..>1373
                     /locus_tag="LSX49_005199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001773871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7171441.1"
                     /translation="MTTVNKKLKKTASGAITWSVIVTQILSPVSLSLIPANSFASSGN
                     KDVTQIYASDEHANKVASFAASAGQSLANNNASSFAVNTLSTQATKEVVDWLQQYGNA
                     RIKLNVDDSFSLKDSSFDFLYPWLDTQDYVLFSQTSLHRTDDRNQTNIGLGIRHFTPD
                     NAMLGANVFYDYDLSRSHSRAGFGVEYWRDYFRLGVNTYFGLSDWKNSRDIDDYLERP
                     ANGWDFSAEGWLPAYPQLGASIQFEKYYGKNVGLFGSDNLQENPYAVTGGISYTPVPL
                     IKFSAQHKQGQSNTHDTTFGVEFNYRPGVSLAEQLSSDNVAVMREVQNRRYDFVERNN
                     NIVLEYKKKHALKISLPESVQGEGESIIPVTLTINNASGGIKSVQWNDSAFTAAGGKI
                     SGNGTSWQITLPAYKSEGVNSWNVGATVQDNRGNVSNYAVMNISVTDSGVSTADSSFT
                     LDGDSSPT"
BASE COUNT          386 a          257 c          328 g          402 t
ORIGIN      
        1 atgaccactg tgaataaaaa gttaaaaaaa actgcatctg gcgcgattac atggtcggta
       61 attgttaccc agatattatc tccagtttct ctttctttga tcccagcaaa cagttttgca
      121 tcatctggta ataaagatgt tacgcaaatt tatgccagcg atgagcatgc aaataaagtg
      181 gcctcatttg cagcaagtgc aggtcagagc ctggcgaata ataatgcaag tagttttgct
      241 gtaaatactt tatcaactca ggcgacaaaa gaggtcgtcg actggttgca acaatatggc
      301 aatgcgcgca tcaagcttaa tgtcgatgat tctttttcct tgaaggattc atcattcgac
      361 tttttatatc catggctgga tactcaggat tatgtgttat tcagtcagac atcactacat
      421 cgtactgatg accgaaatca gaccaatatt ggtttgggga ttcgtcattt cactcctgat
      481 aacgcaatgt tgggtgcgaa tgttttctat gattacgatt taagtcgtag tcactctcgt
      541 gcaggttttg gggttgagta ctggagggat tatttcaggc ttggtgtaaa tacctatttt
      601 ggtctatctg actggaagaa cagtcgtgat attgatgatt atctggaaag acctgcaaat
      661 ggctgggatt tttctgctga aggatggcta cctgcttatc cgcaattagg ggcatctatt
      721 cagtttgaaa aatattatgg taaaaatgtc gggttatttg gaagcgataa cctgcaggaa
      781 aacccttacg cagttactgg gggaatttct tatacaccag ttcctctgat taagttttct
      841 gcacagcata agcaaggaca gagcaacact cacgatacaa cctttggtgt tgagtttaat
      901 tatcgcccgg gcgtttcctt ggctgaacag cttagcagcg ataatgttgc agttatgcga
      961 gaagtccaga accggcgtta tgattttgtt gaacgaaata acaacattgt tctggagtac
     1021 aagaagaagc atgcactgaa aatcagtttg ccagagtctg ttcaggggga gggggaatca
     1081 atcatccctg taacactgac aatcaacaat gctagtggtg gtatcaagtc tgtacagtgg
     1141 aatgatagtg cattcactgc ggctggcggc aagatcagtg gaaatggcac atcatggcag
     1201 atcactttac cggcttataa aagcgaaggt gtaaattcgt ggaatgttgg agccacagta
     1261 caggataaca gaggcaacgt ttccaactat gccgtgatga atattagcgt tactgatagt
     1321 ggtgtctcga cggctgattc gtcttttaca ctggatggag attcgtcgcc gac
//
LOCUS       DAFGPF010000274         1313 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.281, whole genome shotgun sequence.
ACCESSION   DAFGPF010000274 DAFGPF010000000
VERSION     DAFGPF010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.281"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..264
                     /locus_tag="LSX49_005200"
     CDS             <1..264
                     /locus_tag="LSX49_005200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL7171442.1"
                     /translation="PMGITVDVETANRHGLRWLHDVANQRKHETIQARPCDRWLEEQQ
                     SMLALPPEKKEYDVHPGENLVNFDKHPLHHPLSIYDSFCRGVA"
     gene            264..1043
                     /gene="istB"
                     /locus_tag="LSX49_005201"
     CDS             264..1043
                     /gene="istB"
                     /locus_tag="LSX49_005201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /protein_id="HBL7171443.1"
                     /translation="MMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLE
                     HLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERN
                     ENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQR
                     GVMAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDA
                     ALTSAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE"
     gene            1111..1313
                     /locus_tag="LSX49_005202"
                     /pseudo
     CDS             1111..1313
                     /locus_tag="LSX49_005202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          355 a          346 c          350 g          262 t
ORIGIN      
        1 ccgatgggga tcactgtcga tgttgaaaca gccaaccgcc acggtctgcg ctggctgcac
       61 gatgtcgcta accaacgaaa gcatgaaaca atccaggccc gtccctgcga tcgctggctc
      121 gaagagcagc agtccatgct ggcactgcct ccggagaaaa aagagtatga cgtgcatcct
      181 ggtgaaaatc tggtgaactt cgacaaacac cccctgcatc atccactctc catctacgac
      241 tcattctgca gaggagtggc gtgatgatgg aactgcaaca tcaacgactg atggcgctcg
      301 ccgggcagtt gcaactggaa agccttataa gcgcagcgcc tgcgctgtca caacaggcag
      361 tagaccagga atggagttat atggacttcc tggagcatct gcttcatgaa gaaaaactgg
      421 cacgtcatca acgtaaacag gcgatgtata cccgaatggc agccttcccg gcggtgaaaa
      481 cgttcgaaga gtatgacttc acattcgcca ccggagcacc gcagaagcaa ctccagtcgt
      541 tacgctcact cagcttcata gaacgtaatg aaaatatcgt attactgggg ccatcaggtg
      601 tggggaaaac ccatctggca atagcgatgg gctatgaagc agtccgtgca ggtatcaaag
      661 ttcgcttcac aacagcagca gatctgttac ttcagttatc tacggcacaa cgtcagggcc
      721 gttataaaac gacgcttcag cgtggagtaa tggccccccg cctgctcatc attgatgaaa
      781 taggctatct gccgttcagt caggaagaag caaagctgtt cttccaggtc atcgctaaac
      841 gttacgaaaa gagcgcaatg atcctgacat ccaatctgcc gttcgggcag tgggatcaaa
      901 cgttcgccgg tgatgcagca ctgacctcag cgatgctgga ccgtatctta caccactcac
      961 atgtcgttca aatcaaagga gaaagctatc gactcagaca gaaacgaaag gccggggtta
     1021 tagcagaagc taatcctgag taaaacggtg gatcaatatt gggccgttgg tggagatata
     1081 agtggatcac ttttcatccg tcgttgacag gatgcatacg ccgggttcaa cgagctgtac
     1141 cgggatggcc ggataacgga agccgcctgt tgggctcacg cccgccgtaa aatccacgat
     1201 gtgcacgttc gcaccccgtc agccctgacg gaggaagcgc tgaaacggat cggcgaactg
     1261 tacgccatcg aggcagagat aaggggaatg acggcggagc aacgccttgc cga
//
LOCUS       DAFGPF010000275         1284 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.282, whole genome shotgun sequence.
ACCESSION   DAFGPF010000275 DAFGPF010000000
VERSION     DAFGPF010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.282"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..707
                     /gene="blaOXA"
                     /locus_tag="LSX49_005203"
     CDS             <1..707
                     /gene="blaOXA"
                     /locus_tag="LSX49_005203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class D beta-lactamase"
                     /protein_id="HBL7171444.1"
                     /translation="CFLLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEI
                     IDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDY
                     GNQDFSGDKERNNGLTEAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMY
                     LQDLDNSTKLYGKTGAGFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSS
                     IKAKKNAITILNTLNL"
     gene            845..>1284
                     /locus_tag="LSX49_005204"
     CDS             845..>1284
                     /locus_tag="LSX49_005204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBL7171445.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDV"
BASE COUNT          422 a          270 c          268 g          324 t
ORIGIN      
        1 gttgtttttt actttacgat gcatccacaa acgctgaaat tgctcaattc aataaagcaa
       61 agtgtgcaac gcaaatggca ccagattcaa ctttcaagat cgcattatca cttatggcat
      121 ttgatgcgga aataatagat cagaaaacca tattcaaatg ggataaaacc cccaaaggaa
      181 tggagatctg gaacagcaat catacaccaa agacgtggat gcaattttct gttgtttggg
      241 tttcgcaaga aataacccaa aaaattggat taaataaaat caagaattat ctcaaagatt
      301 ttgattatgg aaatcaagac ttctctggag ataaagaaag aaacaacgga ttaacagaag
      361 catggctcga aagtagctta aaaatttcac cagaagaaca aattcaattc ctgcgtaaaa
      421 ttattaatca caatctccca gttaaaaact cagccataga aaacaccata gagaacatgt
      481 atctacaaga tctggataat agtacaaaac tgtatgggaa aactggtgca ggattcacag
      541 caaatagaac cttacaaaac ggatggtttg aagggtttat tataagcaaa tcaggacata
      601 aatatgtttt tgtgtccgca cttacaggaa acttggggtc gaatttaaca tcaagcataa
      661 aagccaagaa aaatgcgatc accattctaa acacactaaa tttataaaaa atctaatggc
      721 aaaatcgccc aacccttcaa tcaagtcggg acggccaaaa gcaagctttt ggctcccctc
      781 gctggcgctc ggcgcccctt atttcaaacg ttagacggca aagtcacaga ccgcgggatc
      841 tcttatgacc aactactttg atagcccctt caaaggcaag ctgctttctg agcaagtgaa
      901 gaaccccaat atcaaagttg ggcggtacag ctattactct ggctactatc atgggcactc
      961 attcgatgac tgcgcacggt atctgtttcc ggaccgtgat gacgttgata agttgatcat
     1021 cggtagtttc tgctctatcg ggagtggggc ttcctttatc atggctggca atcaggggca
     1081 tcggtacgac tgggcatcat ctttcccgtt cttttatatg caggaagaac ctgcattctc
     1141 aagcgcactc gatgccttcc aaaaagcagg taatactgtc attggcaatg acgtttggat
     1201 cggctctgag gcaatggtca tgcccggaat caagatcggg cacggtgcgg tgataggcag
     1261 ccgctcgttg gtgacaaaag atgt
//
LOCUS       DAFGPF010000276         1276 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.283, whole genome shotgun sequence.
ACCESSION   DAFGPF010000276 DAFGPF010000000
VERSION     DAFGPF010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1276
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.283"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..779
                     /gene="yeeO"
                     /locus_tag="LSX49_005205"
     CDS             <1..779
                     /gene="yeeO"
                     /locus_tag="LSX49_005205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
                     /protein_id="HBL7171446.1"
                     /translation="AVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPASV
                     ESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGV
                     GQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNAL
                     FMPIWSASWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGM
                     FADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEKKPVVSE"
     gene            880..955
                     /locus_tag="LSX49_005206"
     tRNA            880..955
                     /locus_tag="LSX49_005206"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:913..915,aa:Asn,seq:gtt)
BASE COUNT          297 a          258 c          338 g          383 t
ORIGIN      
        1 gcgcagttgc aattttgtgg gtgctggcga ttggttttaa tcctgcgcta aggatttcgt
       61 taaagagcta ttttaaaccg ctgaatttta gcattatctg ggaagtcatg gggattggta
      121 ttccagcgag tgtcgaatca gtgttattta ccagtggtcg gttattaacc caaatgttcg
      181 ttgccgggat ggggaccagc gttattgccg gaaattttat cgcgttctca attgcggctc
      241 ttatcaactt acccggaagt gcgctcggtt ctgcttctac gatcattaca ggccgaaggt
      301 tgggggtagg gcagatagcg caagcagaga ttcagttgcg gcatgtgttc tggctgtcca
      361 ctcttggatt aacggccatc gcctggctaa cggctccctt tgccggggtt atggcatcgt
      421 tttacaccca ggatccacag gttaaacacg tcgttgtgat tctgatttgg ctaaatgctt
      481 tatttatgcc tatttggtcc gcctcatggg tgctacccgc tggatttaaa ggtgctcgtg
      541 atgcccgtta cgccatgtgg gtttcgatgt tgagcatgtg gggttgtcgg gttgtagtcg
      601 gttatgtgct gggaatcatg cttggctggg gtgtggttgg tgtctggatg ggaatgtttg
      661 ccgactgggc tgtgcgggcc gtgctgtttt actggcgaat ggttactgga cgttggctat
      721 ggaaataccc tcgatccgag ccgcaaaagt gtgaaaaaaa gccagttgtg tcggaataaa
      781 cgacaaaatg cagattattt cagcaaacga tttcaaattt aaaaaacagg ctttgacatt
      841 gtgggtgggc atcgctaata ttcgcctcgt tctcacgatt cctctgtagt tcagtcggta
      901 gaacggcgga ctgttaatcc gtatgtcact ggttcgagtc cagtcagagg agccaaattt
      961 tagttttgag acatctctat gagtctcagg acagttaaaa aataaaaatt atttttaccc
     1021 ggtcactttg taaaaaagtg gccgggtttt tgatttctgt gtttcgtgcg cttaatcgag
     1081 tctcacgctt cagtgagcaa attgcccctc cccaacagac atcacgattc acaaggtcaa
     1141 aaattctgtt ccatgaagta ccgtacaaag ataaagagaa aaatgcctta tgcgggatgt
     1201 agctgtcgcg tctttatcgg gaaactatac gtaattgcca ctttgtcttc ggtaatcaga
     1261 aaaagaagac ctgcca
//
LOCUS       DAFGPF010000277         1250 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.284, whole genome shotgun sequence.
ACCESSION   DAFGPF010000277 DAFGPF010000000
VERSION     DAFGPF010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1250
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.284"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            89..1168
                     /gene="waaB"
                     /locus_tag="LSX49_005207"
                     /gene_synonym="rfaB"
     CDS             89..1168
                     /gene="waaB"
                     /locus_tag="LSX49_005207"
                     /gene_synonym="rfaB"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,6-galactosyltransferase"
                     /protein_id="HBL7171447.1"
                     /translation="MKIAFIGEAVSGFGGMETVIRDVITTFRQQHIYSEMFFFCRNDK
                     MDKGWLEGIKYSCSFSNIRLGFLRRAKHIHALSKWLQDYQPDVVICIDVISCLYAAKA
                     RKKSGIDVPVFSWPHFSLDHKKHAEYITCADYHLAISSGIKQQMINRGVPESTINVIF
                     NPVEAKDTVIPGPEEGETATFIYVGRMKFEGQKRVKDLLDGLSQAQGDWKLHVLGDGS
                     DFEKCQAYGRELKIDNRIVWHGWQKHPWEVVRQDIKKVSALLLTSSFEGFPMTLLESM
                     SWGIPCISADCVSGPGDIIQPDVNGHLYQPGDIAGFVTLLNKYIAGEIHIEHEKIPAS
                     IDKFYQSKYYDRLHNIIISAISRRK"
BASE COUNT          383 a          195 c          270 g          402 t
ORIGIN      
        1 gataaaatga tgtcaacaat tgtttatgat tttatagaaa aataaaaccg ttaaaacagt
       61 gagttttact caattaatga gagtttcaat gaaaatagca tttatcggcg aagctgtttc
      121 tggatttggc ggcatggaaa cggtcattcg tgatgttatt actaccttca ggcaacaaca
      181 tatctatagt gaaatgtttt tcttttgtcg taatgataaa atggataagg gatggctgga
      241 aggtattaag tactcgtgtt cattttccaa tattcgctta ggttttttgc gtcgggcgaa
      301 acatattcat gctttaagca aatggcttca agattatcag ccagatgttg ttatttgtat
      361 tgacgttatc tcgtgtttgt atgcggccaa agcacgtaaa aaatcaggaa ttgatgtgcc
      421 agtattttca tggccgcatt tttctttaga tcacaaaaaa catgctgaat atatcacctg
      481 tgcagactat catttagcca tcagctctgg cattaaacag caaatgatta atcggggtgt
      541 accagaatcg acgataaatg ttatttttaa tccagtcgaa gctaaagaca cagtcattcc
      601 tgggcctgag gaaggtgaaa cggcaacgtt catttatgtt gggcgtatga aattcgaggg
      661 ccagaagagg gttaaagacc tgcttgatgg tttatcacaa gcgcaaggtg actggaaact
      721 ccatgtactg ggtgatggtt ctgattttga aaaatgccag gcatatggta gagaattgaa
      781 gattgataat cgaattgtct ggcatggttg gcaaaaacat ccatgggagg tagtgcgtca
      841 ggatattaag aaagtcagtg cattgttatt aacctcatct tttgaaggtt ttccaatgac
      901 cttacttgaa tcgatgtcat gggggattcc gtgtatcagt gccgattgtg tctccggtcc
      961 tggtgacatt attcaacctg atgtcaatgg ccatttgtat caaccgggag atattgctgg
     1021 ttttgttact cttctaaata aatatatagc aggtgaaatt catatcgaac atgaaaaaat
     1081 tcctgcgtcg atcgataagt tttatcaatc taagtattat gatagattac ataatataat
     1141 tatttctgct atttcccgga ggaaataatg cagcaggtat ttttccagga aactgagtat
     1201 ctaaattcag ttattgatta taatcataaa gtagaaacag aaaatctttg
//
LOCUS       DAFGPF010000278         1213 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.286, whole genome shotgun sequence.
ACCESSION   DAFGPF010000278 DAFGPF010000000
VERSION     DAFGPF010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1213
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.286"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            19..>1213
                     /locus_tag="LSX49_005208"
     rRNA            19..>1213
                     /locus_tag="LSX49_005208"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          339 a          261 c          377 g          236 t
ORIGIN      
        1 aacatcttcg ggttgtgagg ttaagcgact aagcgtacac ggtggatgcc ctggcagtca
       61 gaggcgatga aggacgtgct aatctgcgat aagcgtcggt gaggtgatat gaaccgttat
      121 aaccggcgat ttccgaatgg ggaaacccag tgtgtttcga cacactatca ttaactgaat
      181 ccataggtta atgaggcgaa ccgggggaac tgaaacatct aagtaccccg aggaaaagaa
      241 atcaaccgag attcccccag tagcggcgag cgaacgggga ggagcccaga gcctgaatca
      301 gtgtgtgtgt tagtggaagc gtctggaaag gcgcgcgata cagggtgaca gccccgtaca
      361 caaaaatgca catattgtga gctcgatgag tagggcggga cacgtggtat cctgtctgaa
      421 tatgggggga ccatcctcca aggctaaata ctcctgactg accgatagtg aaccagtacc
      481 gtgagggaaa ggcgaaaaga accccggcga ggggagtgaa aaagaacctg aaaccgtgta
      541 cgtacaagca gtgggagcct cttaatgggg tgactgcgta ccttttgtat aatgggtcag
      601 cgacttatat tctgtagcaa ggttaaccga ataggggagc cgaagggaaa ccgagtctta
      661 actgggcgtt aagttgcagg gtatagaccc gaaacccggt gatctagcca tgggcaggtt
      721 gaaggttggg taacactaac tggaggaccg aaccgactaa tgttgaaaaa ttagcggatg
      781 acttgtggct gggggtgaaa ggccaatcaa accgggagat agctggttct ccccgaaagc
      841 tatttaggta gcgcctcgtg aattcatctc cgggggtaga gcactgtttc ggcaaggggg
      901 tcatcccgac ttaccaaccc gatgcaaact gcgaataccg gagaatgtta tcacgggaga
      961 cacacggcgg gtgctaacgt ccgtcgtgaa gagggaaaca acccagaccg ccagctaagg
     1021 tcccaaagtc atggttaagt gggaaacgat gtgggaaggc ccagacagcc aggatgttgg
     1081 cttagaagca gccatcattt aaagaaagcg taatagctca ctggtcgagt cggcctgcgc
     1141 ggaagatgta acggggctaa accatgcacc gaagctgcgg cagcgacact atgtgttgtt
     1201 gggtagggga gcg
//
LOCUS       DAFGPF010000279         1164 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.287, whole genome shotgun sequence.
ACCESSION   DAFGPF010000279 DAFGPF010000000
VERSION     DAFGPF010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1164
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.287"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            244..795
                     /gene="papX"
                     /locus_tag="LSX49_005209"
     CDS             244..795
                     /gene="papX"
                     /locus_tag="LSX49_005209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PapX"
                     /protein_id="HBL7171448.1"
                     /translation="MRACTQTVCFSNMENNEMNNTDTLEKIIRHQKNKDPAYPFREHL
                     LMQLCIRTNKRMQDNISEFLGVYGINHSAYMVLTTLFAAENHCLSPSEISQKLQFTRT
                     NITRITDFLEKAGYVKRTDSREDRRAKKISLTSEGMFFIQRLTLAQSMYLKEIWDYLT
                     HDEQELFEVINKKLLAHFSDASS"
BASE COUNT          381 a          216 c          249 g          318 t
ORIGIN      
        1 gacctcacac gaacaacgat ggtttaccgc cttgcttaca tgaagaaaag tggaaacagg
       61 ttattccggt gtcctgattt tgtgaaccac tacaataatc ctttttcaca gacttgtcag
      121 cagccagcat ttatgttctt ttacctgcgg gaatttatcc gtctgcctgt cgggactact
      181 ctgtcataca gaaatcaggt aggaataaat tgtagtggaa agtcgatgtt taccggatga
      241 ctgatgcgcg cttgtacaca gacagtgtgt ttcagtaata tggagaataa tgaaatgaat
      301 aacacagaca cattagaaaa aataatcaga caccaaaaaa acaaagaccc cgcatatccc
      361 tttcgggaac atttgttgat gcagctctgt attcgcacaa ataaaagaat gcaggataat
      421 atatctgaat ttctgggggt gtatggaata aatcactcag catatatggt tctcaccaca
      481 ttattcgcag cggagaacca ttgtctgtca ccttcagaga taagccagaa acttcagttt
      541 accagaacta atattacccg cattacagat tttttagaaa aagccggata tgtaaaaagg
      601 acggatagca gggaggatcg ccgtgctaaa aaaatcagtc tgacatctga aggtatgttt
      661 tttattcaga ggctcactct tgcacaaagc atgtatctga aagaaatctg ggattatctg
      721 acccatgatg aacaggaact gtttgaagtc attaataaaa agttactggc acatttttct
      781 gatgccagct cataaagtgc gaaatatctg aggatgctgg atagcttcag gcaagagaat
      841 aatgattctt gcagatgtgt ttttccggat acaaaaacaa aagtaaaaaa ttgcagcgcc
      901 aggccacctt tcaaagcagg gaggcctgta ccgcgtcgaa aatttcagcc agttaatgta
      961 attgtctgaa ccaggcactt cgcccgggca ggagaaggag cgtggttgcg gtcatcctgt
     1021 atactgaagt cgttatgaag gaataataca aataattgcc cgttttctct gtacgataga
     1081 ggcaggtgtg tatgattgca ttactatgtt tttgtgatat aaaaaactaa atggtgagat
     1141 atgcatttta aaatataaca aaaa
//
LOCUS       DAFGPF010000280         1134 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.288, whole genome shotgun sequence.
ACCESSION   DAFGPF010000280 DAFGPF010000000
VERSION     DAFGPF010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1134
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.288"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            228..776
                     /locus_tag="LSX49_005210"
     CDS             228..776
                     /locus_tag="LSX49_005210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171449.1"
                     /translation="MKTYHLSSANRSAEHYIMFSYGVSLRLSNYLFNSKPVARDFFKH
                     LKGTTQRGLTDKHLDNLDYFKGLGAYHIVSKRFVEAMKSYLKEDVTFHAMQVSGRNTS
                     HDLYLLQVNKTLPIIKETSFDLNNDRVFSPPIFKKNHDISFLIAREENVLMNHIVIVS
                     DEFVSLCARHQLKINFRQTLTE"
     gene            864..>1134
                     /locus_tag="LSX49_005211"
     CDS             864..>1134
                     /locus_tag="LSX49_005211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000758621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171450.1"
                     /translation="MKKVYFVHRDKNAIERQSDGVEFCFIPEFNDGRIYFYCHEYDIF
                     WRSIKDAGDYAWCCNFHLKGIIRPATLIEISNSDLISYIDSIKEYE"
BASE COUNT          390 a          185 c          189 g          370 t
ORIGIN      
        1 atttctataa atttacgata tttattagat aattatgccg agtattcaat ttggagatga
       61 tcaggcagac tatccgtttt tatcggaggg agtcatctgg ctaaggttga tgtgatatgt
      121 ccgttttatc gtcaaggtta aacggaatat aagaaatgac cacctcgctt cagtccttat
      181 agagagcgac tgtcgtaacc ttctcccaag tttaaagaga accagatatg aaaacttatc
      241 atctaagttc agcaaacaga agtgcagaac attatataat gttctcatat ggtgtatcat
      301 tacgactatc taattacctt tttaacagta aaccggttgc aagagatttt tttaaacatt
      361 taaaaggaac tacgcagcga ggtttaacag ataagcattt agacaattta gattacttca
      421 agggcttagg agcttatcac attgtatcta aacgcttcgt cgaagcaatg aaatcatatt
      481 taaaggaaga tgtaactttt catgcaatgc aagtctcagg aaggaatact tctcacgact
      541 tatacctttt acaagtcaat aaaactttgc caataattaa agaaacatct ttcgatttaa
      601 acaatgatcg tgtattttcg ccacccattt tcaaaaaaaa tcatgacata tcatttctaa
      661 tagccagaga agagaatgtc ttaatgaatc atattgtcat cgtcagcgat gaatttgttt
      721 ctttgtgtgc acgacatcaa ttaaaaataa acttccgaca aacacttacg gaataaatta
      781 aacttaagac atccatcaat attattgtta gtatacattc gatctcagcg tatttattaa
      841 caaaaacgac aggaaatatt catatgaaaa aagtttattt tgttcatcgt gataagaatg
      901 caattgaacg tcaaagtgac ggtgtagaat tttgtttcat ccctgagttc aatgacggaa
      961 gaatttattt ctattgtcat gaatatgata tattttggcg ttcaatcaag gatgctggtg
     1021 actatgcctg gtgctgtaat ttccatctaa agggaattat acgtccggca actcttattg
     1081 agatatcaaa ttccgattta atatcttata ttgactctat taaagaatat gaaa
//
LOCUS       DAFGPF010000281         1134 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.289, whole genome shotgun sequence.
ACCESSION   DAFGPF010000281 DAFGPF010000000
VERSION     DAFGPF010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1134
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.289"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..170
                     /locus_tag="LSX49_005212"
     CDS             <1..170
                     /locus_tag="LSX49_005212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pilus assembly protein"
                     /protein_id="HBL7171451.1"
                     /translation="EIAEALAVTDYQARYYLLLLEKEGVVQRSPLRRGMATYWLLKGE
                     KQAGQNCSSTT"
     gene            complement(821..>1134)
                     /locus_tag="LSX49_005213"
     CDS             complement(821..>1134)
                     /locus_tag="LSX49_005213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBL7171452.1"
                     /translation="VSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYMER
                     LKEAKLLASTGSTGDSYDNAMAESINGLYKAEVIHRKSWKNRAEVELATLTWVDWYNN
                     R"
BASE COUNT          282 a          292 c          248 g          312 t
ORIGIN      
        1 cagaaattgc ggaggcgctg gcggtaacgg attatcaggc acgctattac ctgttattac
       61 tggaaaaaga aggtgtggtt cagcgctctc cattaaggcg aggcatggca acatactggc
      121 ttctgaaagg agagaagcag gcggggcaga actgttcttc cacaacttaa taactcaatc
      181 tgtgggcatg cttcactgaa acagataaaa gttacatcag agtgcagatt cagttttgca
      241 gcattcatca caaaatagaa atttagtatt ttatgtcaga atacttcaca tgataataaa
      301 aacctgtctg gatttactgc atggccagac attacaaaat acaaacgcca taaacttcat
      361 tcagccttct tgctgtccgg taacggaggc tgctttttcg ttacaccttt ccccggcagc
      421 atcagtagca gtaatttata gattctacga actgagactg tctgtccggg gagaacgtac
      481 acagcccgac acaatgtacc agtcaataat atccggtttc tgattccctg cctgacagac
      541 cactctctgg caactttgta ttcagttcat ctactactgg agacagattt ataaaatcca
      601 actccacgat ctttgaccgt ccgcatcccc tactctctgt gctgcggtca tcggttaatt
      661 ccagcgtccg tccgttacga tcagatatta ctgaaccgcc ccgggtttcc tggagagtgt
      721 tttatctgtg aactcaggct gccagatcat tgtttccgat ggaagcataa taagcttttt
      781 ctgcttctgc cggaggagta tggcccagcc ttcccagcaa tcatcgattg ttataccagt
      841 ccacccacgt gagtgtggcc agttccactt ctgcacggtt tttccagctc ttacggtgta
      901 ttacctccgc tttgtaaaga ccattgatgc tctccgccat cgcgttgtca tacgagtcgc
      961 ctgtactccc tgttgatgcc agcagttttg cttcttttaa tcgctccata taggccagtg
     1021 acacatactg agagccttta tcgctgtgat ggatggtgcc ggacggacgg cgggcccaca
     1081 acgcctgctc cagcgcatcc agcacgaatg tcgtttccat agacgatgag accc
//
LOCUS       DAFGPF010000282         1049 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.290, whole genome shotgun sequence.
ACCESSION   DAFGPF010000282 DAFGPF010000000
VERSION     DAFGPF010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.290"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            1..579
                     /locus_tag="LSX49_005214"
     CDS             1..579
                     /locus_tag="LSX49_005214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL7171453.1"
                     /translation="MKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQ
                     HPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVR
                     TIQSATWFSAGKKLTVDKRFLQCGNEIYSAIKDLQRKAPDKNIVIFTHNHCLTYIAKD
                     KRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH"
     gene            complement(618..1043)
                     /gene="nudI"
                     /locus_tag="LSX49_005215"
     CDS             complement(618..1043)
                     /gene="nudI"
                     /locus_tag="LSX49_005215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HBL7171454.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGE
                     RIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSAN
                     RDVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL"
BASE COUNT          287 a          245 c          227 g          290 t
ORIGIN      
        1 ttgaagtcaa aaaaatattt catcatttta ctggcgctcg ctgcaattgc cggactgggg
       61 actcatgccg cctggagtag caatggtttg ccacgcatcg acaataaaac actggccaga
      121 ctggcacagc agcacccggt tgtcgttttg tttcgccatg ctgaacgttg cgatcgttca
      181 accaatcaat gcttgtcaga taaaacaggt attacggtca aaggtaccca ggatgcccgt
      241 gaactgggca acgcttttag tgctgatatc cctgattttg atctctattc cagtaatacc
      301 gtccggacta ttcagtcggc gacctggttt tcggcgggta aaaagctgac ggtagataaa
      361 cgatttcttc aatgcggtaa tgagatttat agtgcaatta aagacttaca acgcaaagca
      421 cctgataaaa atatcgttat ttttacccat aatcattgcc tgacatatat tgctaaagat
      481 aagcgtgatg cgacatttaa acctgattat ctggatggtt tagtcatgca tgtggaaaaa
      541 ggcaaagttt atctggatgg ggaattcgtt aaccactaaa ttttcaatct gacagccagt
      601 gatggctgtc atcattgtta aagaagacct ttcaaacgta acgtttttcg ggtggcaaca
      661 ttcaaatcat aatgcaccag atcttcaggt tttacccacg cgtagtcctg aaactcttcg
      721 tttattttca catctcggtt ggcagaaacg cagtcaaaaa tcaggtaaat catataaatc
      781 tcttccttgc gaccatctgc atacgtcttg gtgcgaatat catcgctgaa ggtccacggc
      841 gtgatttctg tcaaaagcag ctgttctccc agttcttcgc gaatttcgcg gcgtagtgcc
      901 tcttcaattc gttcgccagg ctccacgccg ccacccgaaa gcgcccattg accggggaaa
      961 acgccgcgat cgtcggccat tttacacagc aaataagcac catcattttg aatcaaaggg
     1021 catacaatag tccgttgtcg cacaggggt
//
LOCUS       DAFGPF010000283         1039 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.291, whole genome shotgun sequence.
ACCESSION   DAFGPF010000283 DAFGPF010000000
VERSION     DAFGPF010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1039
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.291"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            32..1039
                     /locus_tag="LSX49_005216"
                     /pseudo
     CDS             32..1039
                     /locus_tag="LSX49_005216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558234.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          294 a          244 c          266 g          235 t
ORIGIN      
        1 ggacataatc tgacatctga aggtgcagtt tatgaaacat tcatttgaag taaaacttgc
       61 cgctgtaaat cattacctgg ctggtcatgc aggcatcatt tctacggcaa aactctttca
      121 actttctcac accagcctct cacactggat taatcttttt cttcttcacg gtcctcgggc
      181 actggattgc agacacaagc gtagctattc tcctgaagat aaactttgcg tggttcttta
      241 tgctctcggg cattctgagt ctctaccccg ggtagcagcc cggtttaaca ttcccagcca
      301 caacacggtt aaaaactgga taaaaggcta ccgcaaatct ggtaatgagg cctttatcag
      361 gcgcaggaag gagaaaagca tgacccgttc tgatgatacc catgaaaacg aggcaaacat
      421 gacgccggaa gagatgaaga atgagctgcg ttatcttcgc gcagaaaatg catatctgaa
      481 agccatgcag gagcatcttc tggaaaaaaa gcgccaggag ctggagaaaa aacgaaagtc
      541 atccagagcc tgaggtacgg acactgccag tctgacctgt taaaggccgc agggctggcc
      601 agaagcacgc tgtactacca gctgtcactg cagaaggcta aggacaagta tgctgatgtg
      661 aaacagctca tagcctccat cttccatgaa caccggggat gttatgggta ccggcggatc
      721 cattgtgagc ttcagaaaag aggtcttaag ttcagtggca aaacggtgcg aaaactgatg
      781 caacagctcg gcctgaagtc tcctgtgcgt ctgaagaaat accggtctta ccggggaaat
      841 atgggactcg ctgcagaaaa tatccttcag cgactgttca aagcggcagc tccctgtgag
      901 aaatgggtga cagatatcac cgaattcagg gctggcggac aaaaactgta cctgtccccg
      961 atacttgatt tgtttaacgg ggaaatcgtg gcgtgggaaa cggcctgcag gcctacagag
     1021 gagctggtga agcggatgt
//
LOCUS       DAFGPF010000284         1014 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.292, whole genome shotgun sequence.
ACCESSION   DAFGPF010000284 DAFGPF010000000
VERSION     DAFGPF010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.292"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..701
                     /locus_tag="LSX49_005217"
     CDS             <1..701
                     /locus_tag="LSX49_005217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171455.1"
                     /translation="DVFSKDNFFLKKCLLDNYSDSIDTGISFLTTDHEAIVFQSSGRF
                     VLTKDVIDICNSSEEKHAEVYPPVNIGMIADMNFRKNVALIYHPMGNISGKMVYQAEL
                     SKFVKKNYRSSSFLTEVDPEKIQYLITGRFFYNGSYRDLEKKSYSGPFDLVSGVISPD
                     AKYVDPFGLGCDIDKVNHSIPHVYEISTAQRVAFKSDPALSAIINKEQIDKKCRQLLK
                     ASASLKDLGGYLSQ"
BASE COUNT          337 a          146 c          199 g          332 t
ORIGIN      
        1 ttgatgtttt cagcaaagat aattttttct taaagaaatg tcttctggat aactacagtg
       61 acagtataga tacaggcatt tcatttttaa caacagatca tgaagcaatt gtttttcagt
      121 catcgggtcg gtttgtttta acaaaagatg taatcgatat atgtaattct tctgaagaaa
      181 agcatgcgga agtttatcca cctgtcaata ttgggatgat tgctgacatg aacttcagga
      241 aaaatgttgc tcttatatat cacccaatgg gtaatatttc aggaaaaatg gtatatcagg
      301 ctgagttgtc aaagtttgtt aaaaaaaatt atagatcaag cagcttctta acggaggttg
      361 atcctgaaaa aatacagtac ctgataacgg gtaggttttt ttacaatggt agttacagag
      421 atttagaaaa aaaaagttat tcaggcccat ttgatctcgt ctcaggcgtt atctctcctg
      481 atgcaaaata tgtagatcct ttcggtctgg ggtgtgatat tgataaggtc aatcatagta
      541 taccacacgt gtatgaaata tccacagcac aacgagttgc atttaaaagc gatccagcgt
      601 tatctgcgat aataaataaa gaacaaatag ataaaaagtg tcggcagtta ttaaaagcat
      661 ctgcatcttt gaaagattta ggtggatatt taagtcagta gaatatgtca ccgttactct
      721 actgtgctat aggagatagc gaagaagagt tttttcaatc aaatattgcc agagttttat
      781 tattggttga agaagacttg aagacgttgg tgaacaattt caagaggcta ttttttaatg
      841 ccaatggtat tgctgcagga taagtttggc attttatctc aggtaacttt ataaattatt
      901 tccataaatg cggaaaaatc acaaaaagct tttttatttc ttcattcttt tatgataggt
      961 cgtcaggaac aacactgacc agcatattta ggaggagagc gtatatattt ttca
//
LOCUS       DAFGPF010000285         1010 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.293, whole genome shotgun sequence.
ACCESSION   DAFGPF010000285 DAFGPF010000000
VERSION     DAFGPF010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1010
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.293"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..391
                     /locus_tag="LSX49_005218"
     CDS             <1..391
                     /locus_tag="LSX49_005218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBL7171456.1"
                     /translation="KVITFGTFDVLHIGHINILKRAKKMGDYLIVGVSSDYLNFSKKQ
                     RYPVYPETERLEIIRSLKFVDEVFIEESLELKGEYIKKFKADILVMGDDWLGRFDEYK
                     ELCEVSYLPRTVGISTTELISQIKRYG"
     gene            407..>1010
                     /locus_tag="LSX49_005219"
     CDS             407..>1010
                     /locus_tag="LSX49_005219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171457.1"
                     /translation="MKFHSEIKNSIKNAKKFKGILFVNIISYLLLTIAIRKGHSKEIL
                     KFKWLILLFGGSVAKYFVARASFLNGDYIFAKKLYQEIIKVNPIHTDSYYGLADVYRL
                     TGNKLEAKDVLIQVFNFSDRLKTWLLLANLVDTKKDYDELLNHWERECSYRNILKYHY
                     DVNDYLIIAALRAKLYEEALNRVKVLLGSINSEAFILPKTS"
BASE COUNT          355 a          110 c          201 g          344 t
ORIGIN      
        1 taaagttatc acctttggta catttgatgt attacatata ggtcatataa atatcttaaa
       61 aagggcaaaa aaaatggggg actatctaat agttggcgtc tcatccgatt atttgaattt
      121 ctcaaaaaaa cagaggtatc ctgtttatcc ggaaactgag cgtcttgaaa taattaggtc
      181 cttaaaattt gtagatgaag tttttattga agagtcattg gaattaaagg gcgagtatat
      241 taaaaaattt aaggcagata tcttagtgat gggagatgat tggctagggc gatttgatga
      301 atataaggaa ttatgtgaag tatcatatct gccaagaact gttggtattt caacgacaga
      361 actaatttct caaatcaaaa gatatggtta attttggaga gggattttga aatttcattc
      421 agagataaaa aactctataa aaaatgcgaa gaaattcaaa ggtattttat ttgttaatat
      481 aatatcttat ctgctgctaa caattgcgat aagaaaaggt cattcgaaag agattttaaa
      541 atttaagtgg ttgattttac tttttggcgg gagtgtcgct aaatattttg ttgctagggc
      601 ttcatttctt aatggtgatt atatatttgc taagaaatta tatcaagaga taattaaggt
      661 aaacccaata catactgata gctattatgg gttggctgat gtttatagac taaccggaaa
      721 taaattagaa gcgaaggatg tactcattca agtttttaat ttttctgatc gtttgaaaac
      781 ttggctatta ttggcgaact tggttgatac aaaaaaagat tatgatgaat tattgaatca
      841 ttgggaaagg gaatgttctt ataggaatat acttaagtat cattatgatg tgaacgatta
      901 ccttataatt gctgcgttaa gggctaaact atatgaagaa gcattaaatc gggttaaagt
      961 attgttggga agtataaatt ctgaggcttt tatcttacca aaaactagca
//
LOCUS       DAFGPF010000286         1000 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.294, whole genome shotgun sequence.
ACCESSION   DAFGPF010000286 DAFGPF010000000
VERSION     DAFGPF010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.294"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..334)
                     /locus_tag="LSX49_005220"
     CDS             complement(<1..334)
                     /locus_tag="LSX49_005220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171458.1"
                     /translation="MQLPVKLLMSLISLVSVIARAGKYKNYIRDEIKYWRYTSYKGGE
                     FPEGFTDEKFSSAIYNGRIFTMKRLHTLMLFLAVLFTGFNVEAASVKQALSCDPNARA
                     EQPGACPTT"
     gene            complement(470..>1000)
                     /locus_tag="LSX49_005221"
     CDS             complement(470..>1000)
                     /locus_tag="LSX49_005221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin reductase"
                     /protein_id="HBL7171459.1"
                     /translation="TKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQGTMFGDG
                     GMGGWRNMQGNTPVTPLVDAGCNMVIVTHLSDGSLWDRQAFPVTTILEIRPRKRLKYA
                     GDGDNSGGLLSFTLAHTDAWRQQGYEDTMLTMEHIRKPLAARQVLSRSETVLQKSLEI
                     TEEADLALRNAMARIK"
BASE COUNT          240 a          266 c          229 g          265 t
ORIGIN      
        1 acgttgttgg acacgctcca ggttgttcag cccgggcgtt tgggtcgcag ctgagcgctt
       61 gtttcacgct cgctgcttcc acgttaaagc cagtaaacag aaccgccaga aataacatca
      121 gggtatgtaa acgtttcatt gtaaatattc ttccgttgta aatggcgctg gaaaatttct
      181 catcagtgaa accttccgga aattcccccc ccttgtatga tgtatatcgc cagtatttta
      241 tttcatcccg gatgtaattt ttatatttcc cggcacgtgc aataacgctg accagagata
      301 taaggctcat taataacttt acaggtaatt gcataattaa atttccagtg agtgaattga
      361 caggtgaggg gtaaaacttt ctctcaggta atatatatct gaaaatattt tcaataacac
      421 cagccaggaa aaacaccacc acaggcggtg gcgtttcttt ggggcgtctt tatttaatcc
      481 gggccatcgc gtttctcagt gccaaatctg cctcttccgt tatctccaga cttttctgca
      541 acaccgtttc tgaccgggac agtacctgac gtgctgccag cggtttccgg atatgctcca
      601 tcgtcagcat cgtgtcttca tagccctgct gacgccaggc gtcggtatgt gccaacgtga
      661 aactgagcag accgccgctg ttgtcaccat cacctgcata tttcagcctt ttccggggac
      721 ggatctcaag gattgtggtg accggaaaag cctggcgatc ccataaagaa ccgtcactca
      781 gatgcgtcac aatcaccata ttgcatccgg catcgaccag aggcgtcaca ggggtatttc
      841 cctgcatatt tcgccatcct cccataccac catcaccgaa cattgtcccc tgaacctcac
      901 ggggacggaa cagcaggggc agcgcggctg acgcaagcag agcctctttc tgctgtccgc
      961 ggggcaggct ctggatatgc tgaaaaacgg cgtttttcgt
//
LOCUS       DAFGPF010000287          965 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.295, whole genome shotgun sequence.
ACCESSION   DAFGPF010000287 DAFGPF010000000
VERSION     DAFGPF010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.295"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..731
                     /gene="ydeO"
                     /locus_tag="LSX49_005222"
     CDS             <1..731
                     /gene="ydeO"
                     /locus_tag="LSX49_005222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HBL7171460.1"
                     /translation="HAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFNE
                     NTIKKYLQCTNIQTVTMPVPAKFLRASNVPTGLLNEMIAYLNSEERNHHNFSELLLFS
                     CLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCLYISESLLKKKL
                     KQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNSPKR
                     VSKEYRCQRHTGMNTDNTMNALAS"
BASE COUNT          298 a          191 c          188 g          288 t
ORIGIN      
        1 atcatgcctt caacgctaac attttagata aagattacgc cttctctgac ggcgagatcc
       61 tgatggtaga taacgctgtt cgcacgcatt ttgaacctta tgagcggcat ttcaaagaaa
      121 tcggatttaa tgaaaatacc attaaaaaat atctacaatg cactaacatc cagacagtga
      181 cgatgcctgt tcctgcgaag tttttacgtg cttcaaatgt accgactgga ttgcttaatg
      241 aaatgattgc ttatctcaac tcggaagaac gcaatcatca taatttttca gagcttttgc
      301 ttttttcttg cctgtctatt tttgccgcat gcaaaggttt cattacacta ttaactaacg
      361 gtgtgctatc cgtttccggg aaagtaagaa atattgtcaa catgaagctg gcgcacccat
      421 ggaagctgaa agatatttgt gactgcctgt acatcagtga aagcctgttg aagaaaaaac
      481 taaagcaaga gcaaacgaca ttctcacaga ttcttttaga tgccagaatg cagcacgcga
      541 aaaatttgat acgcgtagaa ggttcagtca ataaaattgc tgaacaatgc ggttatgcca
      601 gtacatctta ttttatttat gcgtttcgca aacatttcgg caacagtccg aagagagttt
      661 ctaaggagta ccgttgtcaa aggcacacgg gtatgaacac ggacaacacg atgaatgctt
      721 tagctagttg attatttgct aacgagtagt caaccacaca cgctgcgtaa gaattaaatg
      781 gggcagccat tccctgcccc gcgttgtttc caggcgatat atttcttgaa ataaataagt
      841 gacagccatc acatatttat gcattttcat aacctgttgc atgattattt atgatctcag
      901 ctcggcaatt tgtcagtgaa atacaataat ttattaaata tcaatagatt agttgtttat
      961 cggcg
//
LOCUS       DAFGPF010000288          954 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.296, whole genome shotgun sequence.
ACCESSION   DAFGPF010000288 DAFGPF010000000
VERSION     DAFGPF010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.296"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..846)
                     /locus_tag="LSX49_005223"
     CDS             complement(<1..846)
                     /locus_tag="LSX49_005223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL7171461.1"
                     /translation="MSLLKHSIWNVAGYFIPTLIAIPAFGLIARKIGVELFGLYTLAM
                     IFIGYASIFDAGLTRAVVREIALLKNRVDDCNTIIVTSIIAVIFLGFIGGGGVFLLKG
                     DIIELLNISPIYYADSIKSLVLLSSLIPVFLVTQILLAELEGREYFGILNIQKSVGNS
                     LIAGLPALFVLINQTLFSAIIGVAIARVICLWLSYIMSRERITIDISFFSITVLKRLF
                     RYGGWVTISNIISPILASMDRFILSHIQGASKISFYTVPNELVTRLGIVPGSLGKAVF
                     PKLSHA"
BASE COUNT          328 a          199 c          138 g          289 t
ORIGIN      
        1 tgcatgactt aattttggaa aaacagcttt cccaagagag cctggaacta ttccaagcct
       61 agttaccagc tcattaggga ctgtatagaa tgatattttt gatgctccct ggatatggga
      121 tagaataaat ctatccatac tcgctaatat aggagatatt atgttactta tagttaccca
      181 cccgccatat ctaaataacc gctttaaaac agttattgaa aaaaatgaga tatcgatagt
      241 tattctttcc ctgctcataa tgtagcttaa ccacaagcat ataactcttg caatcgctac
      301 accaataatt gcagaaaaaa gcgtttgatt aattaaaaca aataatgcag gtaaccctgc
      361 aattaaagaa ttccctacac ttttttgtat atttagaatc ccaaaatatt cccgaccctc
      421 aagctctgct aatagtattt gcgtgactaa gaatacaggt atcagagatg ataataatac
      481 tagagacttt atcgaatcgg cgtaatatat tggtgagata tttaacagtt caataatatc
      541 gcctttaagc agaaacactc ccccgcctcc gataaaccct aaaaatatca cagcgataat
      601 agaagttact attatcgtat tacaatcgtc cactctgttt tttagtaatg ctatttcacg
      661 cacaacagct cttgttaacc cagcatcaaa tatacttgca taccctataa aaatcattgc
      721 taacgtatac aaaccaaata gttctacacc aattttcctc gcaattaatc caaaggcggg
      781 aattgcaatt aatgttggta taaagtagcc cgcaacattc catatactat gttttaagag
      841 agacatttca aaactcactt agttcaaatc tttccccatt tgcatcctta tcagacagag
      901 tgatcagtgc tgtgctcggc catttaatat taagcaagag gtcattccat ataa
//
LOCUS       DAFGPF010000289          901 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.298, whole genome shotgun sequence.
ACCESSION   DAFGPF010000289 DAFGPF010000000
VERSION     DAFGPF010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.298"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..759
                     /gene="dsdC"
                     /locus_tag="LSX49_005224"
     CDS             <1..759
                     /gene="dsdC"
                     /locus_tag="LSX49_005224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DsdC"
                     /protein_id="HBL7171462.1"
                     /translation="QLFVRSHRKVELTHEGKRVYWALKSSLDTLNQEILDIKNQELSG
                     TLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDDAPS
                     AQLTHNFLMDEEILPVCSPEYAHRHDLTNTVINLRHCTLLHDRQAWSNDSGTDEWHSW
                     AQHYAVNLPTSSGIGFDRSDLAVIAAMNHVGVAMGRKRLVQKRLASGELVAPFGDMTV
                     KCHQHYYITTLPGRQWPKIEAFITWLREQVKTTS"
BASE COUNT          238 a          193 c          225 g          245 t
ORIGIN      
        1 cagttgtttg ttcgttccca tcgcaaagtg gaattaacgc acgaggggaa acgcgtttat
       61 tgggcgctaa aatcgtcgct ggataccctg aatcaggaaa ttctggatat caaaaatcag
      121 gagttatcgg gaacgttaac tctgtattcc cggccctcta tcgcccaatg ctggttggtg
      181 cccgcattag gtgactttac acgccgatat ccgtctattt cgctcaccgt gctcactggt
      241 aatgacaatg tcaatttgca acgtgccgga atcgatttgg cgatctactt tgatgatgcg
      301 ccgtcagcgc aactgaccca taactttctg atggatgaag aaatcttgcc agtttgtagc
      361 ccggagtacg ctcatagaca tgatttaacc aacacggtaa ttaacctgcg tcactgtacg
      421 ttgctccatg acagacaggc atggagcaac gactccggta cggatgaatg gcatagttgg
      481 gcgcaacatt atgcggttaa tttgccgaca tcttctggaa ttggctttga tcgttctgat
      541 ttagccgtta tcgccgcgat gaatcatgtt ggggtggcga tgggaaggaa acgcctggta
      601 caaaaaaggc ttgccagtgg tgagctcgtc gcgccgtttg gcgatatgac ggtgaaatgc
      661 catcagcatt attacatcac cacattaccg ggcaggcagt ggccaaaaat tgaggcattt
      721 attacttggt taagagaaca ggtaaaaacc acttcataat gaataagacc acgagttcct
      781 ggtgtgcctt attcggcact gctagtgcga atttaataat ttacggtttt tacgtggttt
      841 tagggataaa cacaagaatg gtgtcccctg caggaatgtg attaatgaat taagaaattg
      901 a
//
LOCUS       DAFGPF010000290          896 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.299, whole genome shotgun sequence.
ACCESSION   DAFGPF010000290 DAFGPF010000000
VERSION     DAFGPF010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..896
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.299"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..>896)
                     /locus_tag="LSX49_005225"
     CDS             complement(<1..>896)
                     /locus_tag="LSX49_005225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBL7171463.1"
                     /translation="KSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLD
                     EPDSLKRLSKMISDLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAV
                     LMAEACNIGLEPLIRSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQI
                     WGGGEVASADGMRFVTPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTL
                     RDSIFVLEGLLEQETGLNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWR
                     MDHDADYGVLNDIARGQSDPRK"
BASE COUNT          221 a          238 c          222 g          215 t
ORIGIN      
        1 tttttcgggg atctgattgc cctctggcaa tatcattcag cacgccatag tcggcatcat
       61 ggtccattcg ccagaaaacc gaagcaccgg catcagccag gcgtggagaa aactggtatc
      121 ccagcagcca gaaaaggcca aagacaagtt cgctggcacc tgctgtatcg gtcataattt
      181 cggttggatt cagcccggtc tcctgttcca gaagaccttc cagcacaaag atagagtccc
      241 tcagcgtccc cggtataacg atgccatgaa agccggaata ctgatcggac acaaagttgt
      301 accaggtgat ccctctgtta ttaccaaagt atttgcggtt cggtccggca ttgattgttc
      361 tgactggcgt aacaaagcgc attccatctg cagatgccac ttctcctcca ccccatatct
      421 gtgccagtgg cagcgttgcc tgaaaatcaa ccagtctggc attagcgctg gtgatagttt
      481 cagcccgcag atagttcgct tttgtccagt tcagccggtg tcgggtcagt gcaggaacat
      541 ttgatctgat cagtggttcc agaccgatat tgcaggcttc agccatcagc acggcgctga
      601 tgctgacggg cagatcatca actctggcac tggcttcact agcatggaaa aactcatcag
      661 caaatccggt atgggcgtta atttcgagca gcaactccgt taaatccacc ggagggagta
      721 gatcactgat cattttgctc agtcgtttca gactgtccgg ctcatcaaga ctggcgaggg
      781 gagaaattgt caaccggggc ttcgggccag aaacatcgag ttcgacagcc tcattttcgc
      841 aaagacgtgc agcaacctgt ctgtaacgac tatcaagctg atgacccaga gatttt
//
LOCUS       DAFGPF010000291          880 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.300, whole genome shotgun sequence.
ACCESSION   DAFGPF010000291 DAFGPF010000000
VERSION     DAFGPF010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.300"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(109..633)
                     /locus_tag="LSX49_005226"
     CDS             complement(109..633)
                     /locus_tag="LSX49_005226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HBL7171464.1"
                     /translation="MFSKNKITIAAISALLISGTAMAQTSSGSVSATGSFNAATCSVT
                     LPNATASFGTVTNQEVNAAKAYQKIKSVTADQGISVTDCTTPASLTVATTNFQSNGYV
                     YPALNEATGNQQKDFALWMKVGDKGVSSYNAPIELANGTYPIELQMIKISNNYNKNHT
                     GAWSAQYTLTATYN"
BASE COUNT          284 a          148 c          157 g          291 t
ORIGIN      
        1 gaaaaaaata tgaaagataa tattgtaata ttgtattttt tcattttata ttgtcacatt
       61 aaagaatgct gaatatacag gcatgagtaa tcatgcctgt taaatatatt agttataagt
      121 tgcagtcaaa gtgtattgcg cactccatgc accagtatga tttttattgt agttatttga
      181 tattttaatc atttgcaact cgattggata tgtaccatta gcaagttcga ttggtgcatt
      241 ataagaagat acacctttat caccgacttt catccaaagc gcaaaatcct tttgttgatt
      301 accggtagcc tcgtttagag caggataaac atagccatta gactggaaat tagtagttgc
      361 taccgttagt gatgcaggag tggtacaatc ggtaacacta atcccctgat ctgcggttac
      421 actttttatt ttctggtacg cttttgcagc atttacctct tgattcgtta ctgtgccaaa
      481 agatgctgtt gcattaggca gggtaacact gcaagtcgcg gcattaaaag aaccagtagc
      541 ggagacagaa ccactgcttg tctgggccat tgcggtacca gaaataagca gagccgaaat
      601 agctgcgatg gtgattttat tcttagaaaa cattttcaac ctcaatcttg attttcttaa
      661 atttttccta tgtgtatagt gatgggcaaa gagatgtgag aataaaactt tcaaaaatta
      721 gcaacacatc ccaatgcctc ttttctattc ttcaaaaaaa aaagattaat tcaagtcata
      781 aaaatacaac catttgatac ttatttgtac atgacgggat ttttgctgaa ttgtcattcc
      841 ttaagtacaa aatagcaatt ctaaaaaata gaatattttg
//
LOCUS       DAFGPF010000292          877 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.301, whole genome shotgun sequence.
ACCESSION   DAFGPF010000292 DAFGPF010000000
VERSION     DAFGPF010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.301"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>877
                     /locus_tag="LSX49_005227"
     CDS             <1..>877
                     /locus_tag="LSX49_005227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7171465.1"
                     /translation="LKYSAATGGLIAVSELAKRVSGKTNRKLVATMLSLAVAGTVNAA
                     NIDISNVWARDYLDLAQNKGIFQPGATDVTITLKNGDKFSFHNLSIPDFSGAAASGAA
                     TAIGGSYSVTVAHNKKNPQAAETQVYAQSSYKVVDRRNSNDFEIQRLNKFVVETVGAT
                     PAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFINGESKISTNSAYSHDLLS
                     ASLFEVTQWDSYGMMIYKNDKTFRNLEIFGDSGSGAYLYDNKLEKWVLVGTTHGIASV
                     NGDQLTWITKYNDKLV"
BASE COUNT          289 a          167 c          180 g          241 t
ORIGIN      
        1 cttaaatata gtgctgccac tggcggactc attgctgttt ctgaattagc gaaaagagtt
       61 tctggtaaaa caaaccgaaa acttgtagca acaatgttgt ctctggctgt tgccggtaca
      121 gtaaatgcag caaatattga tatatcaaat gtatgggcga gagactatct tgatcttgca
      181 caaaataaag gtattttcca gcccggagca acagacgtaa caatcacttt aaaaaacgga
      241 gataaattct ctttccataa tctctcaatt ccggattttt ctggtgcagc agcgagtggc
      301 gcagctaccg caataggagg ttcttatagt gttactgttg cacataacaa aaagaaccct
      361 caggccgcag aaactcaggt ttacgctcag tcttcttaca aggttgttga cagaagaaat
      421 tccaatgatt ttgagattca gaggttaaat aaatttgttg tggaaacagt aggtgccacc
      481 ccggcagaga ccaaccctac aacatattct gatgcattag aacgctacgg tatagtcact
      541 tctgacggtt caaaaaaaat cataggtttt cgtgctggct ctggaggaac atcatttatt
      601 aatggtgaat ccaaaatctc aacaaattca gcatatagcc atgatctgtt aagtgctagt
      661 ctatttgagg tcacccaatg ggactcatac ggcatgatga tttataaaaa tgataaaaca
      721 tttcgtaatc ttgaaatatt cggagacagc ggctctggag catacttata tgataacaaa
      781 ctagaaaaat gggtattagt cggaacaacc catggtattg ccagcgttaa tggtgaccaa
      841 ctgacatgga taacaaaata caatgataaa ctggtta
//
LOCUS       DAFGPF010000293          875 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.302, whole genome shotgun sequence.
ACCESSION   DAFGPF010000293 DAFGPF010000000
VERSION     DAFGPF010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.302"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..>875)
                     /locus_tag="LSX49_005228"
     CDS             complement(<1..>875)
                     /locus_tag="LSX49_005228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005758964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171466.1"
                     /translation="LSMLFNIEQALTFKVVLSIYSILIMAYVSSCYAQTLWLCSEEIL
                     KRSVFYLFAFLCLIGIISILLQKTEIIHDKSMILFPEPSAFALVFIPIFSFCLYYTRG
                     GGLLLLYILSLGIALGIQNLTMLVGIVISVFVMKKITIRQTIVILLGAWIFSMILSDL
                     DISYYTSRLDFKNTTNLSVLVYLSGIERAFLNFITSYGLGIGFQQMGVNGEIGIYQQI
                     LAELDAPMLNIYDGSFISSKLISEFGVIGALMCIFYFFYFSRFYLRFKKSKRYSPQYI
                     LAYSFYMCFFIPLFI"
BASE COUNT          357 a          154 c          121 g          243 t
ORIGIN      
        1 gtataaaaag agggatgaag aaacacatgt agaagctata tgctaaaata tactgcggtg
       61 aatatctctt actttttttg aaacgcagat aaaatcggga aaaataaaaa aaatagaaaa
      121 tacacattaa tgcaccaata accccaaact cagatattaa cttagaagaa ataaatgagc
      181 catcgtatat atttaacata ggggcatcaa gttcagctaa aatttgttga tatattccta
      241 tctccccatt cactcccatt tgttgaaaac caataccaag accataactt gtaataaaat
      301 tcaagaaagc tctttcaatt cctgaaagat atacaagcac tgataggttc gtagtatttt
      361 taaaatcaag ccgcgatgta tagtaagaaa tgtctaaatc acttaatatc atggaaaaaa
      421 tccatgcccc caaaagtata acaatagttt gccttatagt tatttttttc atcacaaaaa
      481 cactaatcac aatgcctacc aacattgtta aattctggat acctaacgca atacccaaag
      541 ataatatata gagcaatagt agcccccccc ctcttgtata gtataaacaa aatgaaaaga
      601 taggtataaa aaccaatgca aatgctgatg gttcaggaaa aagaatcata cttttatcat
      661 gtataatctc agtcttctgt aaaagaatac ttataatgcc aataaggcaa agaaatgcga
      721 acaaataaaa gacggatctc ttaagtattt cttcagaaca taaccacaac gtctgtgcat
      781 aacaagagga gacgtatgcc attattaaga tgctatatat tgaaagtaca actttaaatg
      841 ttaaagcctg ttcaatatta aatagcatac ttaac
//
LOCUS       DAFGPF010000294          870 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.303, whole genome shotgun sequence.
ACCESSION   DAFGPF010000294 DAFGPF010000000
VERSION     DAFGPF010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.303"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>870
                     /locus_tag="LSX49_005229"
     CDS             <1..>870
                     /locus_tag="LSX49_005229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL7171467.1"
                     /translation="KEQLEQCARHLDKLNNHMVSKSSTEEDLLREKLNTDFNNPKLHD
                     RLAEVLHKKGRWWQEVDTLKNAIKLDPSIPERYFKLGTALEKMGRFNEASIYYKKGLE
                     FNKKHDAIWYYALGYSLESDETNNVENVRSSKIAYATAISLDKKLNSNKFGIGAFHQY
                     KGRWAKAIDAYEKHTSINPLCAELYYRLGLSYDRCYQWDKAAENYRKALSLDENHPYW
                     HYRLGFVLERSQKYLDAAVAYQFAAQSNIKHISIWYYRSGYAYAKANKYRQSCEMYIK
                     AYDSSQEIYASQI"
BASE COUNT          322 a          128 c          169 g          251 t
ORIGIN      
        1 ggaaagaaca actcgaacag tgtgcaaggc atcttgataa gttaaataat catatggtga
       61 gcaaatcatc tactgaagaa gatttattaa gggaaaaact taatacagac tttaataatc
      121 caaaattaca cgatagactt gctgaggttc ttcataaaaa agggcgttgg tggcaggaag
      181 ttgatacgct gaaaaacgca ataaaattag atccttcaat acctgaacgt tatttcaaac
      241 ttggcaccgc attagaaaag atggggcgtt ttaatgaggc tagtatatat tataaaaaag
      301 gacttgaatt taataaaaaa catgatgcta tttggtatta tgcactcgga tattcgcttg
      361 aatctgatga aacaaacaat gtagaaaatg tccgtagttc taaaatagca tatgcgacag
      421 ctatatcgtt agacaaaaaa ttaaatagta ataaatttgg aataggagca tttcatcaat
      481 ataagggacg ctgggctaag gctattgatg cgtatgaaaa acatacatcc ataaatccat
      541 tatgtgcaga gctatattat aggctcggat tatcttatga tagatgttat caatgggata
      601 aagccgcaga gaattatcgc aaggcattat cactcgatga aaatcatcct tattggcatt
      661 ataggctagg gtttgtttta gagagaagtc aaaagtatct tgatgctgct gttgcttatc
      721 aatttgcagc acaaagtaat atcaaacata tctcgatttg gtactataga tctgggtacg
      781 catatgctaa ggctaataaa tacaggcaat cctgtgaaat gtatataaaa gcatatgact
      841 cttctcagga aatttatgca tcacaaataa
//
LOCUS       DAFGPF010000295          865 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.304, whole genome shotgun sequence.
ACCESSION   DAFGPF010000295 DAFGPF010000000
VERSION     DAFGPF010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.304"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            20..517
                     /gene="ftnA"
                     /locus_tag="LSX49_005230"
     CDS             20..517
                     /gene="ftnA"
                     /locus_tag="LSX49_005230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HBL7171468.1"
                     /translation="MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKIN
                     ELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
                     LDTQN"
     gene            complement(555..794)
                     /locus_tag="LSX49_005231"
     CDS             complement(555..794)
                     /locus_tag="LSX49_005231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HBL7171469.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSEEGFSTDQSKICRH"
BASE COUNT          247 a          216 c          173 g          229 t
ORIGIN      
        1 acctttgtgg agcactatca tgctgaaacc agaaatgatt gaaaaactta atgagcagat
       61 gaacctggaa ctgtactctt cactgcttta tcagcaaatg agcgcctggt gcagctatca
      121 taccttcgaa ggtgctgccg cgttcctgcg ccgtcacgcc caggaagaga tgacgcatat
      181 gcagcgtctg tttgattacc tgactgatac cggcaactta ccgcgtatta ataccgttga
      241 atctccgttt gctgaatatt cctcacttga tgaattattc caggaaacct ataaacacga
      301 acaattaatc acgcagaaaa ttaacgaact ggctcatgct gcaatgacca atcaggacta
      361 cccaacattt aatttcctgc aatggtatgt ttctgagcag catgaagaag agaaactgtt
      421 caaatcgatt attgataaat taagcctggc aggcaaaagt ggcgaaggtc tgtattttat
      481 cgacaaagaa ctctctaccc tcgacacaca aaactaatgc tctccggcgg caggttttct
      541 gccgccgttt caaatcagtg acggcaaatc ttactctgat cggttgaaaa accttcttct
      601 gaaggtataa atttgccttt tgctgccaga aacgccacca actctcccgc agtcatccct
      661 tctgccgagc aggtgtgaaa acgtgcctgt tcaccaaaac gcgctttaat tgctgcttcc
      721 agactggcat gcgtatattg ctcgcctgat tcaatcatca tatttaacac ttcatgaccg
      781 tgaatagagt ccatcgttcc tcctcaaaaa aagcctagcg tagcgattgc tgcttatgaa
      841 gactttgcgc cagcgcagaa ctgaa
//
LOCUS       DAFGPF010000296          842 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.305, whole genome shotgun sequence.
ACCESSION   DAFGPF010000296 DAFGPF010000000
VERSION     DAFGPF010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.305"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            221..819
                     /gene="fimB"
                     /locus_tag="LSX49_005232"
                     /pseudo
     CDS             221..819
                     /gene="fimB"
                     /locus_tag="LSX49_005232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimB"
BASE COUNT          246 a          161 c          190 g          245 t
ORIGIN      
        1 aatatataaa ggtacatagc atgcaagagc atggcgtttg tatggcaaag ttattataag
       61 taactatcgc tactccattt aagttcactc agaagaactg gtccacttac gttagttatt
      121 aagcaaacgt tcgcttttat aaacataatc aggataaaaa tgttggatta ttgctaaccc
      181 agcacagcta gtgcgcgtct gtaattctaa gggaaaaacg atgaagaata aggctgataa
      241 caaaaaaagg aacttcctga cccatagtga aatcgaatca ctccttaaag cagcaaatac
      301 cgggcctcat gcagcacgta attattgtct gactttgctt tgttttattc atggtttccg
      361 ggcgagtgaa atttgtcgat tgaggatttc ggatattgat cttaaggcaa agtgtatatc
      421 catcgattaa aaaaaggctt ttcaacaacg catccgctat tgaacaaaga agttcaggct
      481 ttaaaaaact ggttgagtat ccgtacttcg tacccgcatg ctgagagcga gtgggtattt
      541 ttatctcgta agggaaatcc gctttctcgg caacagtttt accatattat ctcgacttcc
      601 ggtggtaatg ccgggttgtc actggagatt catccgcaca tgttacgcca ttcgtgtggt
      661 tttgctttgg cgaatatggg aatagatacg cgacttatcc aggattatct tgggcatcgc
      721 aatattcgtc atactgtctg gtataccgcc agcaatgcag ggcgttttta cggcatctgg
      781 gatagagcca gaggacgaca gcgtcacgct gttttataga gatagttgag ataccaggga
      841 tg
//
LOCUS       DAFGPF010000297          830 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.306, whole genome shotgun sequence.
ACCESSION   DAFGPF010000297 DAFGPF010000000
VERSION     DAFGPF010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.306"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(366..>830)
                     /locus_tag="LSX49_005233"
     CDS             complement(366..>830)
                     /locus_tag="LSX49_005233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296213.1"
                     /note="WbbJ; catalyzes the transfer of the O-acetyl moiety
                     to the O antigen; part of the lipopolysaccharide
                     biosynthetic pathway; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL7171470.1"
                     /translation="DGSVSFGKGFTSGVGLRVDAFMDAVVSIGENVQINDYVHIAAIN
                     NVIIGRDTLIASKVFISDHNHGIFSKSDIHSSPTIIPSSRPLESAPVYIGERVWIGEN
                     VTILPGACIGNGVVIGANSVVRGEIPNNVIIAGVPAKIVKKYNYERMQWERI"
BASE COUNT          280 a          175 c          120 g          255 t
ORIGIN      
        1 aggttctcct ataatatctc gatagcttaa atatttatag aacggtgcag gattgtggca
       61 ataaacaaat ctatagggta cactaacatt tgctgtaata tcatgtaagc atacccaatg
      121 agttgcctta atcaccttag ataatctatt gcaagttata tattcgaaat ataatctttt
      181 aacccacgaa gacttgactt ctggatactc tataaattca acccacggaa ataattccat
      241 tagttcagca gagctatgaa ccagtgcaat aaatttacat tcggctctat ctttagttgc
      301 tgtaagcaca ttttttagta cggtaaaggg gcctccggtt gtaaaattaa cagccgatat
      361 tacaactata ttctttccca ttgcatacgc tcatagttat attttttaac aattttagct
      421 ggaacaccag caatgatcac attattagga atctcaccac gaacaacact gtttgcgcca
      481 ataactacac cattacctat acacgcacct ggtaatattg tcacattttc gccaatccac
      541 acacgctctc caatatacac aggtgcagat tcaaggggcc tagacgaagg aataatagtt
      601 ggtgaactat ggatatcgga tttagaaaaa ataccatgat tatgatcact aataaatact
      661 ttacttgcta ttaatgtatc tctaccaata atgacattat taatagccgc gatgtgaaca
      721 tagtcattaa tttgaacatt ttctccaatg gaaactacgg catccataaa tgcatcaact
      781 cgtaatccta cacctgatgt aaaacctttt ccaaaactaa cacttccatc
//
LOCUS       DAFGPF010000298          822 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.307, whole genome shotgun sequence.
ACCESSION   DAFGPF010000298 DAFGPF010000000
VERSION     DAFGPF010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..822
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.307"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            64..405
                     /locus_tag="LSX49_005234"
                     /pseudo
     CDS             64..405
                     /locus_tag="LSX49_005234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774705.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT          273 a          156 c          158 g          235 t
ORIGIN      
        1 ctacagagta atttacgata tcttgatagc ggttctgctc aaagccaaat aaccatcaat
       61 gatctagcga atgtagaaat atctgctcct tcgctaaatg ttcaagattt aatagtcaag
      121 agtctcaaag cttttgatga caaaatcaca acactttcat ccatgaacca aaccttggaa
      181 caaatgtccc aaaccctgtt caaatcctgg tttgtggatt ttgatccagt gattgataac
      241 gctctggatg caggaaatcc aatcccggaa gccctgcaaa ctcgcgccaa attgcgtcaa
      301 aaagtacgta atagtgcaga ttttaaaccg cttccggcgg aaattcgctc gcttttccca
      361 agtgaatttg aagaaacgga gttgggttgg gtgccaaagg ggtggaaaga agggacgctt
      421 ccagagatag cttttataaa ctccacatcg tggactaata aaaatcaacc agattatatc
      481 aattatgtag atctctctaa tgcgaaagat ggcagaatat actcaattga aaaattatca
      541 tttaatgatg ctccaagtcg agctcgaaga atattaaaaa aagatgatct gatttttggc
      601 cttgtcagac ctgctaacag atcatttgca tatgtacatg ttgatggtct aacgggtagc
      661 acaggctttg ccgttattag agcccaaaag acgatatata aaaatttcat ttattacttt
      721 gtgacctatg ataaaaatat agaagaacta gcgagaattg ctgatggtgg agcatatcct
      781 gctataaaac ctgatgatat ttgtacatta cctctaatta tt
//
LOCUS       DAFGPF010000299          821 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.308, whole genome shotgun sequence.
ACCESSION   DAFGPF010000299 DAFGPF010000000
VERSION     DAFGPF010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.308"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            64..780
                     /locus_tag="LSX49_005235"
     CDS             64..780
                     /locus_tag="LSX49_005235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL7171471.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGTDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQKVYHNVANL"
BASE COUNT          276 a          140 c          172 g          233 t
ORIGIN      
        1 ccgaattaac acatgttaac gatttaccag taatgtaaat aaattttcga ggagatcatt
       61 ccagtgggac gtaaatgggc caatattgtt gctaaaaaaa cggctaaaga cggtgcaacg
      121 tctaaaattt atgcaaaatt cggtgtagaa atctatgctg ctgccaaaca aggtgaaccc
      181 gatccagaat taaacacatc tttaaaattc gttattgaac gtgcaaaaca agcacaagtt
      241 ccaaagcacg ttattgataa agcaattgat aaagccaaag gcggcggaga tgaaacgttc
      301 gtgcagggac gttatgaagg ctttggtcct aatggctcaa tgattatcgc tgagacatta
      361 acttcaaatg ttaaccgtac gattgctaac gttcgcacaa ttttcaataa aaaaggcggc
      421 aatatcggag cggcaggttc tgtcagctat atgtttgaca atacgggtgt gattgtattt
      481 aaaggaacag accctgacca tatttttgaa attttgcttg aagctgaagt tgatgttcgt
      541 gatgtaactg aagaagaagg taatattgtt atttatactg aacctactga ccttcataaa
      601 ggaatcgcgg cgctaaaagc agctggaatc actgagttct caacaacaga attagaaatg
      661 attgctcaat ctgaagttga gctttcccca gaagatttag aaatctttga agggcttgtt
      721 gatgcccttg aagatgacga cgatgtacaa aaagtttatc ataacgtcgc aaatctctaa
      781 ttatatgtta aagaaatctg tctttatggc agatttcttt a
//
LOCUS       DAFGPF010000300          803 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.309, whole genome shotgun sequence.
ACCESSION   DAFGPF010000300 DAFGPF010000000
VERSION     DAFGPF010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.309"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..715
                     /locus_tag="LSX49_005236"
     CDS             <1..715
                     /locus_tag="LSX49_005236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M23 family peptidase"
                     /protein_id="HBL7171472.1"
                     /translation="HFLGQGAVESSRLRSMQEKSQYQTVDENGRPVGGGIVPDSLRDE
                     NSDLGHWYGAIETEVDGYFSGVKYNSGGGRIAGSYDWILGNCDTEDAQKFRGRGFKQL
                     TGRSNYAEYWVYRAWIDTNSFTAKWWEDPLWRLHDRRRLTRIPANIEEPHRVTRSEYN
                     CIDTGGFFIVKTVDRRGTRSSITRAMDQDSEVIHLNNTTIDTTDEQTIRSVSRAINGG
                     ENGLPDRITFTRAAKKVLI"
BASE COUNT          232 a          139 c          208 g          224 t
ORIGIN      
        1 tcactttctg gggcaagggg cagtggaatc ttcccgttta agaagtatgc aggaaaaaag
       61 ccagtatcaa actgttgatg aaaatggtcg gccagtcggc ggaggtattg ttccggactc
      121 attacgtgat gagaattcgg acttgggtca ttggtatggt gcaattgaga ctgaggtcga
      181 tggatacttc tctggtgtta aatataattc tggtggagga cgaattgcag gctcatatga
      241 ctggatacta ggaaactgcg acactgagga tgcccagaag tttcgtgggc gaggttttaa
      301 gcagttaact ggtcgatcaa attatgccga atattgggtc tatcgtgcct ggatagatac
      361 gaatagtttt accgctaagt ggtgggaaga ccctctgtgg cgcttacatg atcgtcgtcg
      421 tttaactcgc ataccggcta atatcgaaga gcctcacagg gttaccagaa gcgaatataa
      481 ctgtatcgat actggtggat tctttattgt taagaccgtt gatcgtcggg gtactcggtc
      541 aagtattacc agagcgatgg atcaagacag tgaagttatt catttgaaca ataccacgat
      601 agatacaacg gatgaacaaa caataagaag tgtgtcccgt gcaattaatg gtggtgaaaa
      661 tggtttgcca gacaggataa ccttcacacg cgcagctaag aaggttttaa tatgaaaaag
      721 agtttctttt tatttttata tttcatatcc ctgagtgcat atcctggaga tgaaaatgca
      781 tacatatatg gtaacgatgg aac
//
LOCUS       DAFGPF010000301          801 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.310, whole genome shotgun sequence.
ACCESSION   DAFGPF010000301 DAFGPF010000000
VERSION     DAFGPF010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..801
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.310"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            93..>801
                     /locus_tag="LSX49_005237"
     CDS             93..>801
                     /locus_tag="LSX49_005237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBL7171473.1"
                     /translation="MNRIYSLKYCHLTQGLIAVSELASRVSSKTGRKLLAIFIVSALS
                     YGAAEYACAAQMDTRNFWIRDYLDLAQNKGAFQPGAYGVKTPLKNGGEFSFPEVTIPD
                     FSPVSAKGATTAIGNAYSVTASHNGTIHHAIKTQTWGQSDYHYVDRVTKGDFAVQRLD
                     KFVVETAGATEHADFNLSAAEALERYGIEFNGKKQIIGFRVGAGATGVTSYGVGQTYN
                     PLLRSASMFQLNWNNMYA"
BASE COUNT          237 a          151 c          174 g          239 t
ORIGIN      
        1 tgcaattaat aaaggtaatt ggaagctttt tattaataaa aacatagttc tattggtttg
       61 tattatgtta taaacgttat ggagtcttac ccgtgaacag aatatattca cttaagtatt
      121 gtcaccttac tcaagggctt atagctgtat cagaattagc atcccgagta tcctctaaaa
      181 ccggtcgaaa acttctcgct atatttatag tttctgcctt gtcttatggt gcggctgaat
      241 atgcctgtgc agcacagatg gacacccgaa atttctggat ccgtgattat cttgatctgg
      301 cacagaataa aggtgcattt cagcccggag catacggggt aaaaacgcca ttaaaaaatg
      361 ggggagaatt cagttttcct gaagtaacaa tccctgattt ttctcctgta tccgctaaag
      421 gtgcaacaac tgctattggt aatgcctaca gtgttacagc aagtcataat ggcactattc
      481 accatgccat taaaactcag acatggggac agtcagatta tcattatgtt gatcgtgtga
      541 ccaaaggtga ctttgcggtc cagcgtctgg ataagtttgt tgttgaaaca gcgggtgcaa
      601 cagagcatgc tgatttcaac ttatcagcag cagaagcact agagcgttat ggtattgaat
      661 tcaatggaaa gaaacaaata atcggtttcc gcgttggagc tggtgcaacc ggtgttacat
      721 cttatggggt gggacagaca tacaatccat tattacgtag tgcctccatg tttcagttaa
      781 actggaacaa tatgtatgca a
//
LOCUS       DAFGPF010000302          792 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.311, whole genome shotgun sequence.
ACCESSION   DAFGPF010000302 DAFGPF010000000
VERSION     DAFGPF010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.311"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(113..676)
                     /gene="ipbA"
                     /locus_tag="LSX49_005238"
                     /gene_synonym="fimX"
     CDS             complement(113..676)
                     /gene="ipbA"
                     /locus_tag="LSX49_005238"
                     /gene_synonym="fimX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060710320.1"
                     /note="IpbA is also known as HbiF and FimX; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase IpbA"
                     /protein_id="HBL7171474.1"
                     /translation="MTRKYLTQDEVYRLMDAAQSMSFPERNRCLIMMAFIHGFRASEL
                     LDLRLSDIDASGKQLNIRRIKNGFSTTHPLLPDEYNLIKLWLKQRKLIENGVEGDWLF
                     LSRKRRPISRQHFFSIIREAGKRAGLAVKAHPHMLRHACGFALADNGVDTRLLQDYLG
                     HRNIQHTVRYTASNAARFKGVWKKKPR"
BASE COUNT          246 a          153 c          159 g          234 t
ORIGIN      
        1 tagctagaaa tatcaacatg ttatgtgttt tatttaattg aatgggctgt ttttttatgg
       61 aagaattgag gaaaacgtag gaatctgaca ttttgaatca gaaggtactg ttttaacgag
      121 gctttttttt ccacacccct ttaaaacgag cagcattact ggctgtgtat ctgacagtat
      181 gctgaatatt tcgatgaccc agataatcct gaagtagtcg ggtatcgaca ccattgtcag
      241 ccagagcaaa accacaggca tgacgtaaca tatgaggatg tgcttttaca gctaatcctg
      301 cacgttttcc agcctcacga atgatagaaa aaaaatgttg tctgctgata gggcggcgtt
      361 tccgggagag aaaaagccag tctccttcaa ctccgttttc aattaacttc ctctgcttaa
      421 gccacaactt gatcaaatta tattcatcag gaagaagagg atgtgttgtc gagaaaccat
      481 ttttaatacg ccgaatatta agttgttttc cagatgcatc aatatcggat aaacgtaaat
      541 caagaagttc actggcccta aaaccgtgaa tgaaagccat cataattaga cagcgatttc
      601 tttcaggaaa ggacatgctc tgggctgcat ccatcagcct gtagacttca tcctgtgtga
      661 gatattttct cgtcatacgc caccgtgtac agttgtaaaa aaaagagagg cacacccaga
      721 taagtatgcc tgcaatcaga acgttatcga tgtaatctca ttatctcatt aataagattt
      781 tttgaatagt ag
//
LOCUS       DAFGPF010000303          787 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.312, whole genome shotgun sequence.
ACCESSION   DAFGPF010000303 DAFGPF010000000
VERSION     DAFGPF010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.312"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            52..787
                     /locus_tag="LSX49_005239"
                     /pseudo
     CDS             52..787
                     /locus_tag="LSX49_005239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEc52 family transposase"
BASE COUNT          220 a          201 c          208 g          158 t
ORIGIN      
        1 gccacctgaa cagaggtgat atgctcacct cagaacaaca caggtgccat aatgaaaaaa
       61 agaaatttca gcgcagagtt taaacgcgaa tccgctcaac tggtcgttga ccagaattac
      121 accgtggcag atgcagccag cgctatggat gtcggccttt ccacaatgac gcgatgggtg
      181 aaacaattac gtgatgagcg gcagggaaaa acaccaaaag cctcccctat taccccggaa
      241 caaattgaaa tccgtgagct caggaaaaag ctacaacgta ttgaaatgga aaatgaaata
      301 ttaaaaaagg ctaccgcgct cttgatgtca gactccctga acagttctcg ataatcggga
      361 aactcagggc gcgttatcct gtggccactc tctgccatgt gttcggggtc catcgcagca
      421 gctacaaata ctggaaaaac cgtcctgaaa agccagacgg cagacgggct gtattacgca
      481 gccaggtact tgaactgcat ggcatcagcc acggctctgc cggagcaaga agcatcgcca
      541 caatggcaac ccagagaggc taccagatgg ggcgctggct tgctggcaga ctcatgaaag
      601 agctggggct ggtcagctgt cagcagccga cttaccggta taaacgtggt ggtcatgaac
      661 atgttgctat ccctaactac cttgaacggc agttcgccgt gaccgagcca aatcaggtgt
      721 ggtgcggtga tgtgacctat atctggacgg gtaagcgctg ggcgtacctc gccgttgttc
      781 tcgacct
//
LOCUS       DAFGPF010000304          778 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.313, whole genome shotgun sequence.
ACCESSION   DAFGPF010000304 DAFGPF010000000
VERSION     DAFGPF010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..778
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.313"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(32..736)
                     /locus_tag="LSX49_005240"
     CDS             complement(32..736)
                     /locus_tag="LSX49_005240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="HBL7171475.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
BASE COUNT          178 a          208 c          200 g          192 t
ORIGIN      
        1 atgaggcagc cttttgtctt attcaaaggc cttacatttc aaaaactctg cttaccaggc
       61 gcatttcgcc caggggatca ccataataaa atgctgaggc ctggcctttg cgtagtgcac
      121 gcatcacctc aatacctttg atggtggcgt aagccgtctt catggattta aatcccagcg
      181 tggcgccgat tatccgtttc agtttgccat gatcgcattc aatcacgttg ttccggtact
      241 taatctgtcg gtgttcaacg tcagacgggc accggccttc gcgtttgagc agagcaagcg
      301 cgcgaccata ggcgggcgct ttatccgtgt tgatgaatcg cgggatctgc cacttcttca
      361 cgttgttgag gattttaccc agaaaccggt atgcagcttt gctgttacga cgggaggaga
      421 gataaaaatc gacagtgcgg ccccggctgt cgacggcccg gtacagatac gcccagcggc
      481 cattgacctt cacgtaggtt tcatccatgt gccacgggca aagatcggaa gggttacgcc
      541 agtaccagcg cagccgtttt tccatttcag gcgcataacg ctgaacccag cggtaaatcg
      601 tggagtgatc gacattcact ccgcgttcag ccagcatctc ctgcagctca cggtaactga
      661 tgccgtattt gcagtaccag cgtacggccc acagaatgat gtcacgctga aaatgccggc
      721 ctttgaatgg gttcatgtgc agctccatca gcaaaagggg atgataagtt tatcacca
//
LOCUS       DAFGPF010000305          775 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.314, whole genome shotgun sequence.
ACCESSION   DAFGPF010000305 DAFGPF010000000
VERSION     DAFGPF010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.314"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>775
                     /gene="vgrG"
                     /locus_tag="LSX49_005241"
     CDS             <1..>775
                     /gene="vgrG"
                     /locus_tag="LSX49_005241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HBL7171476.1"
                     /translation="RFATDARLKIEVVEFYDDQSGYERGLTLPLRHPSGLFDGETEAV
                     WGLNTAYSVVEKSVTTRDYNYRTATAEMMTEQHDATGGDNTTYGEAYHYADNFLQKGD
                     KEAAESGAFYARIRHERYLNEQAILKGQSTSSLLMPGLEIRVQGDDAPAVFRKGVLIT
                     GVTASAARDRSYELTFTAIPYSERYGYRPALIPRPVMAGTLPARVTSTVKNDIYAHID
                     KDGRYRVNLDFDRDTWKPGYESLWVRQSRPYAGDTYGLHL"
BASE COUNT          179 a          236 c          231 g          129 t
ORIGIN      
        1 ccgctttgcc accgacgccc ggctgaaaat cgaagttgtc gagttttatg acgaccagag
       61 cggctacgag cgcgggctga cactgccgct tcgccatcct tcagggctgt ttgatggtga
      121 aacggaagcg gtatgggggc tgaataccgc gtacagcgtg gtggaaaaaa gcgtcaccac
      181 tcgggactac aactaccgca ccgccacagc agagatgatg acagagcagc atgacgccac
      241 cgggggcgat aacaccacct acggcgaagc ctaccactat gccgacaact tcctgcaaaa
      301 aggcgataaa gaggcagcgg aaagcggcgc gttttatgcc cgtatccgcc acgaacgcta
      361 cctgaatgaa caggccattc tcaaaggcca gagcaccagt tcactgctga tgccggggct
      421 ggaaatcagg gttcagggcg acgacgcgcc agcagtgttc cgcaagggcg tactgattac
      481 cggcgtgacg gccagcgcgg cgcgtgaccg cagctatgag ctgacgttta ccgccatccc
      541 gtactcagag cgctacggct accgcccggc gcttatcccc cgcccggtaa tggccggcac
      601 actcccggcg cgggtcacca gcacggtgaa aaacgatatc tatgcccata tcgacaagga
      661 cgggcgctac cgggtcaacc tcgactttga ccgcgatacg tggaaaccgg gttatgaaag
      721 cctgtgggtg cgccagtcgc gcccgtatgc aggtgacacg tatggcctgc atctg
//
LOCUS       DAFGPF010000306          740 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.315, whole genome shotgun sequence.
ACCESSION   DAFGPF010000306 DAFGPF010000000
VERSION     DAFGPF010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.315"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(90..>740)
                     /gene="dcm"
                     /locus_tag="LSX49_005242"
     CDS             complement(90..>740)
                     /gene="dcm"
                     /locus_tag="LSX49_005242"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBL7171477.1"
                     /translation="KYLQTYSNNVHKEVLCGSISDNETFSKIADKISGFKKLYFDKQL
                     WILGGPPCQGFSTAGNARTMDDPRNSLFMHYKSLLNEIKPNGFIFENVAGLLNMEKGK
                     VFERVKEEFSSTMKTMNGWILNSEHYAIPQRRKRVILVGSNDPLFSIEPPQKLTEDKE
                     SWVSVKDALSDLPPLQHGEDGSGKYYIHHPENDYQLFMRGNITPSEYYERNIKPSL"
BASE COUNT          233 a          125 c          119 g          263 t
ORIGIN      
        1 aaataggaaa agaactggaa tcatattggg aaaatgatcg ttatgttcgc tcaatcccag
       61 aagaatttat agagtaagac atagccctct tataaagagg gttttatatt cctttcataa
      121 tattctgaag gagtaatatt acctctcatg aataattgat agtcattttc ggggtgatgg
      181 atataatatt taccacttcc atcttcacca tgttgcaaag gaggcagatc agataatgca
      241 tcctttacag atacccaaga ttccttatct tctgttaatt tttgtggagg ttcaattgaa
      301 aataaagggt cgtttgaacc aaccaatata accctttttc ggcgctgagg gattgcataa
      361 tgttcagagt ttaatatcca tccattcata gttttcatgg ttgatgagaa ttcttctttg
      421 actctttcaa agaccttacc tttttccata ttcaacaaac cagcaacatt ttcaaaaata
      481 aaaccgtttg gttttatctc atttaagaga gatttataat gcataaaaag tgaatttctt
      541 ggatcatcca ttgttctggc atttcctgcc gtagaaaatc cctggcatgg gggtccacca
      601 agtatccata attgtttatc aaaatataat ttcttaaatc ctgatatttt atctgctatt
      661 tttgaaaaag tttcattatc agaaatgctg ccacataaaa cttctttgtg aacattgttt
      721 gaatatgttt gtagatattt
//
LOCUS       DAFGPF010000307          740 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.316, whole genome shotgun sequence.
ACCESSION   DAFGPF010000307 DAFGPF010000000
VERSION     DAFGPF010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.316"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(1..357)
                     /locus_tag="LSX49_005243"
                     /pseudo
     CDS             complement(1..357)
                     /locus_tag="LSX49_005243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(406..>740)
                     /gene="tnpB"
                     /locus_tag="LSX49_005244"
     CDS             complement(406..>740)
                     /gene="tnpB"
                     /locus_tag="LSX49_005244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013183349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL7171478.1"
                     /translation="SGTKIWLVAGITDMRNGFNGLAAKVQTTLKDDPMSGHVFIFRGR
                     NGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLLEGIDWRQPKR
                     LLTSLTML"
BASE COUNT          149 a          211 c          207 g          173 t
ORIGIN      
        1 gcaggcaaca gccgcttttc gtcacggggt agtgattcag ggaacggctt acgggtgcgg
       61 gtctgacgca acggacgctg tactgccggg tcatacaccc taccagtcag cgtatcgctc
      121 tctatcgctc tctttctgaa gccggttcag atcggcttcc atttgtgcga tacggcggga
      181 gactttttcg gaacgactgc cgaagttcat ccggcggagt ttatccagct gcgcctgcag
      241 atggtctatt tcgcgttcac gctcgttcag cttttccagc agggcacggt tcagcgcctc
      301 ctgttcggca aggagacgtt tcagtgcatt gatatcgtca ggaagtgagc tgctcatacc
      361 gggtatatta ccaggctcat tcagcgtcga ccaggataaa gaggcttaca acatagtcag
      421 ggacgtaagc agtcttttag gctgccgcca gtcgatacct tcaaggagca tcgccagctg
      481 tgccggtgtg aggaacactt tgccatcccg ggctgacggc caggcgaagc ggccgcgctc
      541 cagccgtttg gtcagcagac acagtccatc gccggtagac cagaggagct ttacctgact
      601 gccattacgc ccacggaaga taaaaacgtg acctgacatc ggatcgtctt tcagcgtcgt
      661 ctgcaccttt gccgccaggc cgttgaagcc gtttctcata tcggtgatgc cagcgaccag
      721 ccagatcttt gtccctgatg
//
LOCUS       DAFGPF010000308          703 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.317, whole genome shotgun sequence.
ACCESSION   DAFGPF010000308 DAFGPF010000000
VERSION     DAFGPF010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.317"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(77..>703)
                     /locus_tag="LSX49_005245"
     CDS             complement(77..>703)
                     /locus_tag="LSX49_005245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171479.1"
                     /translation="LSSCLIEKYMNSKLGYPSIYLFSKRSSLKIKRHNTKFSIVNFIR
                     GVFLFPVSAFDKAEHHKTTLHSILIKVFWPQIRDGYINVFSVSTLYRRKGLRGDLFRL
                     AYHYVYEHSKNHQVKMQNYVALYGFCRNITFVFLASVWLLMFLLLLSFLIDINIRLLP
                     FCFLLLFCIAASRVFYYGFVKYYRRYSLEVLMAFAVLQHDKKTSAISS"
BASE COUNT          277 a          117 c          118 g          191 t
ORIGIN      
        1 attgtatgtg aactaataaa atacagacca acacatcatt ctggcaccct tgctaacagg
       61 gtgccaatgt ttcaaatcat gatgaaattg ccgaagtttt tttatcgtgc tgaagtaccg
      121 caaatgccat taaaacctca agagaatagc ggcgataata cttaacaaaa ccataataaa
      181 atactcggga tgcagcaata caaaacaaga gaagaaaaca aaaaggtaac agtctgatat
      241 ttatatctat taaaaaggat agaaggagca ggaacataag caaccagact gaagcgagaa
      301 aaacaaatgt aatgtttcta caaaaaccat acaaagcaac atagttttgc attttcacct
      361 gatgattttt agaatgttca tacacataat gataagcaag gcgaaaaaga tcgcccctca
      421 agcccttacg tcgatatagc gtagatacag aaaaaacatt tatataacca tctcgtattt
      481 gcggccaaaa gactttaata agtatagaat gcagtgtggt tttatgatgt tctgctttat
      541 caaaagctga tacaggaaat aaaaaaactc cacgaataaa attaactata ctgaacttag
      601 tattatgtcg ttttattttc agggagcttc ttttagaaaa cagataaatt gaaggatacc
      661 caagtttact gttcatgtat ttttcaatta aacaggatga tag
//
LOCUS       DAFGPF010000309          698 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.318, whole genome shotgun sequence.
ACCESSION   DAFGPF010000309 DAFGPF010000000
VERSION     DAFGPF010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.318"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>698
                     /gene="tuf"
                     /locus_tag="LSX49_005246"
     CDS             <1..>698
                     /gene="tuf"
                     /locus_tag="LSX49_005246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL7171480.1"
                     /translation="ATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVE
                     MEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDK
                     PFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLD
                     EGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFK
                     GYRPQFYFRTTDVTG"
BASE COUNT          162 a          170 c          199 g          167 t
ORIGIN      
        1 gcgactgacg gcccgatgcc gcagactcgt gagcacatcc tgctgggtcg tcaggtaggc
       61 gttccgtaca tcatcgtgtt cctgaacaaa tgcgacatgg ttgatgacga agagctgctg
      121 gaactggttg aaatggaagt tcgtgaactt ctgtctcagt acgacttccc gggcgacgac
      181 actccgatcg ttcgtggttc tgctctgaaa gcgctggaag gcgacgcaga gtgggaagcg
      241 aaaatcctgg aactggctgg cttcctggat tcttacattc cggaaccaga gcgtgcgatt
      301 gacaagccgt tcctgctgcc gatcgaagac gtattctcca tctccggtcg tggtaccgtt
      361 gttaccggtc gtgtagaacg cggtatcatc aaagttggtg aagaagttga aatcgttggt
      421 atcaaagaga ctcagaagtc tacctgtact ggcgttgaaa tgttccgcaa actgctggac
      481 gaaggccgtg ctggtgagaa cgtaggtgtt ctgctgcgtg gtatcaaacg tgaagaaatc
      541 gaacgtggtc aggtactggc taagccgggc accatcaagc cgcacaccaa gttcgaatct
      601 gaagtgtaca ttctgtccaa agatgaaggc ggtcgtcata ctccgttctt caaaggctac
      661 cgtccgcagt tctacttccg tactactgac gtgactgg
//
LOCUS       DAFGPF010000310          672 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.319, whole genome shotgun sequence.
ACCESSION   DAFGPF010000310 DAFGPF010000000
VERSION     DAFGPF010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.319"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..570)
                     /gene="fimE"
                     /locus_tag="LSX49_005247"
     CDS             complement(<1..570)
                     /gene="fimE"
                     /locus_tag="LSX49_005247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418733.1"
                     /note="upgraded from regulatory protein to switch DNA
                     invertase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimE"
                     /protein_id="HBL7171481.1"
                     /translation="MSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISE
                     LLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDEREAVERWTQERANWKGADRTDAI
                     FISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL
                     GHRNIRHTVRYTASNAARFAGLWERNNLIN"
BASE COUNT          201 a          171 c          138 g          162 t
ORIGIN      
        1 gtttatgaga ttatttcttt cccataatcc ggcaaaacga gcagcattac tggcggtata
       61 acgcacagta tggcgaatat ttcgatgccc gagataatcc tgaattaaac gagtatctgc
      121 accacgctcc gccagttcat aaccgcaagc atgccttaac atatgaggat gagtctgcgt
      181 tacggttcca gcttcaatac cggcatcgcg aataatgcga taggcctgct ggcgagaaag
      241 ccgactcccg cggcgagaaa taaatatagc gtcagtccgg tcagcgcctt tccagttagc
      301 acgttcctgg gtccagcgtt ccacggcttc acgctcatca aaacgtaacg ggtgaacggt
      361 agaaaatccg ttcttcagtc ggcgaatatt tattctacct tcattaaggt caaggtcctg
      421 ataatgcaga tcaagcagtt cactaatacg catcccatgc cgatatgcca acagaataag
      481 acaataatct ctggctcccg ttgccccgta acaaaccgcc tgcatcatgg cctgaacttc
      541 tttaccggta agataacgac gtttactcac aatagtagta ctcctaactg agatatattt
      601 gaatgaatac ctataggaaa cctcaatcgg tcaaaattag cccaatagat aaaaagataa
      661 ccacacacgg ag
//
LOCUS       DAFGPF010000311          663 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.320, whole genome shotgun sequence.
ACCESSION   DAFGPF010000311 DAFGPF010000000
VERSION     DAFGPF010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.320"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
BASE COUNT          222 a           94 c          117 g          230 t
ORIGIN      
        1 ctgttaaatg catatgtgct gataatataa gtatccacta tggaaatcgg ttatcaattg
       61 attatacgta tccaccagaa caaattcttc gatctcttaa taataccgaa cgagagattc
      121 tttacctcta tttcattaag cggagaaaaa taaaagaaat ttcaaagatt acatgtttaa
      181 gtgtaagtaa aatttattat agaataagaa tgataaaaat taaatttggt gctgaaacga
      241 cacggaagct tccaattctt tttaggtgtt atctgtaaca tcaactgatt ttattttcat
      301 gacgtaacta ttatcagagt caattaattt tatcatcata gtgactaatt atttatagtc
      361 tatgaaatta gttgatatgt cgatgcgaaa ctttttaccg ggaagtattc atctttgcgt
      421 tatttccgag tttacagagt ggatatccca tgaaattatg ttgttacaaa gcatgggggt
      481 gactgtatga atagtcaaaa tgctttaagt aatatgaggc ttgctgtgag aggggatata
      541 tccggtaact ctacattggt tcttaaaaag attagattct acaattgtgc cattatttat
      601 cttcgcaatg cccaattact tgttaaaacg atagatgggg gggttattaa tatcccacct
      661 gaa
//
LOCUS       DAFGPF010000312          628 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.321, whole genome shotgun sequence.
ACCESSION   DAFGPF010000312 DAFGPF010000000
VERSION     DAFGPF010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..628
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.321"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..>628)
                     /gene="istA"
                     /locus_tag="LSX49_005248"
     CDS             complement(<1..>628)
                     /gene="istA"
                     /locus_tag="LSX49_005248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="HBL7171482.1"
                     /translation="LQAKSEPPKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVI
                     AREIRDQGYRGGMTILRGFIRSLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLH
                     VFVAVLGYSRMLYIEFTDNMRYDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAY
                     QTGQHRFHPSLWQFGKEMGFSPRLCRPFRAQTKGKVERMVQYTRNSFY"
BASE COUNT          156 a          166 c          165 g          141 t
ORIGIN      
        1 atgtaaaaac tgttacgggt gtactgcacc atccgttcca ccttaccttt agtctgtgcc
       61 ctgaaggggc gacacagtcg gggagagaag cccatctcct tgccgaactg ccacagcgaa
      121 ggatggaacc ggtgctgacc ggtctgatat gcgtcacgtt gcagaaccac agttttcata
      181 ttgtcataca acacttcgcg cggcacacca ccaaagaagc ggaacgcatt acgatggcag
      241 gtctccagcg tgtcataacg catattgtca gtgaattcga tgtacaacat tcggctgtat
      301 ccgagaacag caacgaacac gtgaagcggt gagcggccat tacgcatagt gccccagtca
      361 acctgcatct gtcgtccggg ttcagtttcg aaccgaacgg caggctcctg ctcctgagga
      421 accgagagag aacgaatgaa tcccctgaga atggtcattc cgccacgata tccctggtct
      481 ctgatctcgc gagcgattac cgttgccggg attttgtaag gatgagcatc ggcgatgcgt
      541 tgacgaatat aatcccggta ttcatccagg agtgaagcaa cagcaggtcg cggcgtatat
      601 tttggcggct cagattttgc ctgcaaat
//
LOCUS       DAFGPF010000313          623 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.322, whole genome shotgun sequence.
ACCESSION   DAFGPF010000313 DAFGPF010000000
VERSION     DAFGPF010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.322"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(197..532)
                     /locus_tag="LSX49_005249"
     CDS             complement(197..532)
                     /locus_tag="LSX49_005249"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171483.1"
                     /translation="MTALEQFVNTTTIDMNFNSSDRTKVQQLSQNLSNIYNSMSGVAK
                     AQVIAVNHAGIEKTIDFMNCPVFFETYDFDIIADKVNGLTNDNYTTNPVFDMIKEEML
                     NGTNKNAFI"
BASE COUNT          202 a          100 c          100 g          221 t
ORIGIN      
        1 caggctcaat aaaaatgaac ccacggaaat aaaaccggag aagagatagc ctcgtaagtt
       61 tttatgataa aaatcaaaaa agttaacact tactttaggt gtgtttctgt acaataggta
      121 aagtgcaagc aatgccagga tcgagaatgc aagcagtgta atgtactgat acctcaatct
      181 tttatttatt agccattcat ataaaggcat ttttattcgt cccgttcagc atttcttctt
      241 ttatcatatc aaaaacaggg tttgttgtat aattatcgtt tgtcaatcca ttgactttat
      301 cggcaattat atcgaaatcg tatgtttcaa aaaaaacagg gcagttcata aaatcaatgg
      361 ttttttctat tcctgcatgg tttactgcaa taacctgtgc tttagcaact ccactcatag
      421 aattataaat atttgaaaga ttctgagata gttgttgcac ttttgttctg tcgctagaat
      481 taaaattcat atctattgtg gtggtgttaa caaattgttc aagcgcagtc attggtccac
      541 ctttaaaatc tatataatta aatttaaagc ttgtgctttt aatctctttg aattgacata
      601 aaacactctg aatgttgttt tta
//
LOCUS       DAFGPF010000314          612 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.323, whole genome shotgun sequence.
ACCESSION   DAFGPF010000314 DAFGPF010000000
VERSION     DAFGPF010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..612
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.323"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..>612)
                     /locus_tag="LSX49_005250"
     CDS             complement(<1..>612)
                     /locus_tag="LSX49_005250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBL7171484.1"
                     /translation="FLHTTHLLSPNTHTTNILLDRYDISNIFSGEIKELGYPRIDRTI
                     NLSSERKEYIRRKINANVYDKVVLYAPTWRGIHGKATLDIEKLKNDLEKLADQDCHIV
                     FRGHHMIEKLVSEQNISGITIVPSEIDTNELLGAIDILITDYSSIAFDFFVMNRPVIY
                     YAYDIEQYNNERGLYFPLNELPGTVCFNDVELLNTLSGYLRNE"
BASE COUNT          204 a          117 c           86 g          205 t
ORIGIN      
        1 atttcattac gaagatatcc acttaacgtg ttaagtaact ctacatcatt aaaacaaacg
       61 gttccaggta attcatttag aggaaaatac aaccctctct cattattata ttgctcaatg
      121 tcatacgcat agtaaattac tggtctattc attacaaaaa aatcgaaagc aatacttgaa
      181 taatctgtga taagaatatc aatcgcccct agtaactcat tcgtgtcaat ctcagaagga
      241 acaattgtta taccagaaat attctgctca cttactaatt tttcgatcat atgatgacca
      301 cggaaaacga tatgacaatc ctggtcagcc aacttttcaa gatcgttctt tagtttttct
      361 atatctaaag ttgcctttcc atgtattcct ctccaagttg gagcatacaa gactacttta
      421 tcgtaaacgt tcgcattaat tttcctacgt atatattcct tccgttcaga gctaagatta
      481 atagtccggt caatgcgagg ataacctaac tctttaattt ccccactaaa tatattagat
      541 atatcatacc tatctaataa aatattagtt gtgtgtgtat taggactaag taaatgtgtt
      601 gtgtgaagga aa
//
LOCUS       DAFGPF010000315          606 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.324, whole genome shotgun sequence.
ACCESSION   DAFGPF010000315 DAFGPF010000000
VERSION     DAFGPF010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.324"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>606
                     /locus_tag="LSX49_005251"
     rRNA            <1..>606
                     /locus_tag="LSX49_005251"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          135 c          201 g          118 t
ORIGIN      
        1 ggattagcta gtaggtgggg taacggctca cctaggcgac gatccctagc tggtctgaga
       61 ggatgaccag ccacactgga actgagacac ggtccagact cctacgggag gcagcagtgg
      121 ggaatattgc acaatgggcg caagcctgat gcagccatgc cgcgtgtatg aagaaggcct
      181 tcgggttgta aagtactttc agcggggagg aagggagtaa agttaatacc tttgctcatt
      241 gacgttaccc gcagaagaag caccggctaa ctccgtgcca gcagccgcgg taatacggag
      301 ggtgcaagcg ttaatcggaa ttactgggcg taaagcgcac gcaggcggtt tgttaagtca
      361 gatgtgaaat ccccgggctc aacctgggaa ctgcatctga tactggcaag cttgagtctc
      421 gtagaggggg gtagaattcc aggtgtagcg gtgaaatgcg tagagatctg gaggaatacc
      481 ggtggcgaag gcggccccct ggacgaagac tgacgctcag gtgcgaaagc gtggggagca
      541 aacaggatta gataccctgg tagtccacgc cgtaaacgat gtcgacttgg aggttgtgcc
      601 cttgag
//
LOCUS       DAFGPF010000316          605 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.325, whole genome shotgun sequence.
ACCESSION   DAFGPF010000316 DAFGPF010000000
VERSION     DAFGPF010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.325"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
BASE COUNT          199 a          121 c           72 g          213 t
ORIGIN      
        1 ttgcaccact aataaagctt gaaattaatg ccgtacccat ctaaaagtcc tttgattctt
       61 gcttggttaa caaaatgaca taattttatt taatgccata acaacttaac aatatatcat
      121 aatatgatta ttatggtgta gcttgtcgca tctacgctcc attacaaaca gatgtaagat
      181 ataacctata tgttttagcc agcaaattcg aaagcattca aagtagtctc atcgaactct
      241 cgaaacccta tgtcttcggg tataaaatat ttaaatccat ttgcataata tcgactcatg
      301 tttattatat tctccccatt caccattaag atttgacatt attttcaaca atcggttatt
      361 gcaagattga aatatatttt tacttgacac aatattccat gtagcccagc gattcgactt
      421 acccccaact atacggacaa tctaaattaa atcgatgatt ttttgataca ttctcctctc
      481 tccattactt tatgtttttg ttccccaaaa ataccttgct ctctaaaaaa taattgttct
      541 ttaagttcaa aatcgagatc tacatgagcg ttagatacaa agctaatatg ttgaaatgtc
      601 tttcc
//
LOCUS       DAFGPF010000317          595 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.326, whole genome shotgun sequence.
ACCESSION   DAFGPF010000317 DAFGPF010000000
VERSION     DAFGPF010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.326"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
BASE COUNT          181 a          121 c          118 g          175 t
ORIGIN      
        1 tatcacctga cacacttctc tccgaaatta agaagtattt gactcatcaa gccaataaat
       61 gtgtatagaa tgattatacg ggatagttac aagttcaccg atacggtgca ggactcaatg
      121 gcgatgtcgg tgggagcgtt tgtgtcacga tatgatggac gtcccttctt aatgcagtca
      181 gtgccatact tttactgact gcattaatcc gagagtaaca tcccatgaac acgatcagga
      241 ttgttggtat cgatattgcc aggcctgttt ttcaggccta tatctggatt aatgatgatt
      301 ctgttgcata ggatagaaac acctcatgct ccaaattgca ggatatcgtt caacgattcg
      361 agtccggaac actattcgct atggaggcat gttcaacttc tcattctggg ggatgaacgt
      421 tcagttctat ggaatatccc ctgactattc cctgcacaac agcatcattt ttggtaaaaa
      481 aaataacatt attcttaata tatagaaaag gaactcgtcc tggacgggta caacttatta
      541 aaaatgcata tcattttcac ctcaccggaa aacgattaaa aatcagtaag aattg
//
LOCUS       DAFGPF010000318          571 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.327, whole genome shotgun sequence.
ACCESSION   DAFGPF010000318 DAFGPF010000000
VERSION     DAFGPF010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.327"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..147
                     /locus_tag="LSX49_005252"
     CDS             <1..147
                     /locus_tag="LSX49_005252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HBL7171485.1"
                     /translation="DWCSEEQHPVIWSTTQAAEHLPVRMPRLCSAERLSESMVDEIFQ
                     KGAG"
     gene            144..>571
                     /locus_tag="LSX49_005253"
     CDS             144..>571
                     /locus_tag="LSX49_005253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL7171486.1"
                     /translation="MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGTQISMVSGASIG
                     AFNGAIIAASPDLSEAAVRLEALWDHLGNNQVLSVNRLVYFSLLKKLFQAMNLCQIPG
                     RAGALLTTLLRHISILNGFDNLMAQPLLSDEPLTALLDHYL"
BASE COUNT          124 a          138 c          171 g          138 t
ORIGIN      
        1 gactggtgca gtgaagagca gcatccggtg atctggtcaa ccacgcaggc tgcagaacac
       61 ttaccggttc gcatgcctcg cctctgctct gcagaacgcc tctctgaaag tatggtcgat
      121 gaaatatttc agaagggggc tggatgagta cagaaatgaa aacggggctg gtgctgtccg
      181 gtggcggggc ggtgggcgct tatcaggcgg gagtggttaa ggcactggca gagtgtggta
      241 cacagatcag catggtttca ggggccagca ttggcgcatt caatggtgcc attatcgcgg
      301 cctctcccga tctgtcagaa gctgccgtac gcctggaggc gctctgggat catctgggga
      361 ataatcaggt gctgtcggta aaccgattgg tttacttttc attgctgaaa aaattgttcc
      421 aggcaatgaa cctctgccag atccccggac gtgcaggagc actgcttacg acgcttcttc
      481 gccatatatc gatactcaac gggtttgaca atctgatggc tcagccgttg ttgtcagatg
      541 agcccctgac agcgctgttg gatcattatc t
//
LOCUS       DAFGPF010000319          571 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.328, whole genome shotgun sequence.
ACCESSION   DAFGPF010000319 DAFGPF010000000
VERSION     DAFGPF010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.328"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..>571)
                     /locus_tag="LSX49_005254"
     CDS             complement(<1..>571)
                     /locus_tag="LSX49_005254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171487.1"
                     /translation="AGEGLAIIQDYNGFNVVYVVSNTGTLQRYNMVSSLYGDRLFKER
                     DFSINAFNQFSMSQDYWLIEGYESERSIKYSRNRLELYSVSGDLLRVIYLQNNYSGYI
                     VSDASPDAKNYNKRQGIALGDGFFVASYGAFYYSKMESTYNTYQGIRVFDFSGKLLSE
                     KIFHPNEMMNVLKKMGLTVSRIENEGVIVK"
BASE COUNT          195 a          120 c           58 g          198 t
ORIGIN      
        1 tcttgactat cactccctca ttttcaattc tagaaactgt taagcccatt tttttgagaa
       61 cattcatcat ttcatttgga tggaaaattt tttcagataa aagctttccg gaaaaatcaa
      121 aaactctaat gccttgatat gtattataag tactttccat tttggaatag taaaaggcac
      181 cataactagc aacaaaaaaa ccatcaccta aagctatccc ttgtctttta ttataattct
      241 ttgcatcagg actcgcatct gatacaatat atccagaata attattctgt aaataaatta
      301 ctcttaataa atctccactt actgaatata gttcaagtct atttctacta tactttatac
      361 ttctttcgct ttcataacct tcaataagcc aatagtcttg actcatcgaa aattggttaa
      421 aagcattaat tgaaaaatct ctttccttaa ataatctgtc accatacaag ctactcacca
      481 tattatatct ttgcaaggtt cccgtattcg aaacgacata tacaacatta aacccattat
      541 agtcttgtat aatagccaaa ccttcgccag c
//
LOCUS       DAFGPF010000320          566 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.329, whole genome shotgun sequence.
ACCESSION   DAFGPF010000320 DAFGPF010000000
VERSION     DAFGPF010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..566
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.329"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..376
                     /locus_tag="LSX49_005255"
     CDS             <1..376
                     /locus_tag="LSX49_005255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL7171488.1"
                     /translation="KLASELKNVHFLGYLNATEMVNFYQDSDIICFPSKLETWGLPLS
                     EAKTYKKWIFAADLPYAHEVLYNYSKTRYFPFDDEKILVRYILEYTSKNMHEDIKNSR
                     VNFNNDALTGFEQFIEYILKGN"
BASE COUNT          208 a           78 c           97 g          183 t
ORIGIN      
        1 taaattagct tccgaactga aaaatgtaca tttcctcggt taccttaatg caaccgagat
       61 ggttaacttt tatcaagatt cagatattat ttgtttccca tcgaaactag aaacgtgggg
      121 attaccatta tcagaagcta aaacatacaa aaaatggata tttgcggcag acttacctta
      181 tgctcatgaa gttttatata actattcaaa aactagatat tttccatttg acgatgagaa
      241 aatacttgtt cgctacatat tagagtacac aagtaaaaat atgcatgaag atataaaaaa
      301 tagtagggtg aattttaata atgatgcatt gactggtttt gaacagttta ttgaatatat
      361 cctcaagggg aactgacgtg gtttatatta taatcgtttc acatggccat gatgactata
      421 tagaaaatct tttattaaat ttaaagttgc cctctggaag atttaaaata atagttcgtg
      481 ataacaaaag ttcaatggtt ttaaaaaaaa catgcgaaaa aaattgcgta acctatttgc
      541 atggagggca atatggattt ggacat
//
LOCUS       DAFGPF010000321          553 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.330, whole genome shotgun sequence.
ACCESSION   DAFGPF010000321 DAFGPF010000000
VERSION     DAFGPF010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.330"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..440
                     /locus_tag="LSX49_005256"
     CDS             <1..440
                     /locus_tag="LSX49_005256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HBL7171489.1"
                     /translation="GLISEGCGSYASIGNKYQINHVDEIFVLQFDHSLSREYNVVHHP
                     IKFYKPIDKSSPLLNAALSENEELSAVFNFYRINSGGCIERFYTIELQGAHLSNILTC
                     YPHSITHAGNQPEEVIVLNYKNITWKHHIASTESYSCWEERIF"
BASE COUNT          188 a           81 c          105 g          179 t
ORIGIN      
        1 aaggtttgat ctctgagggt tgtggttcgt atgcatctat tggtaataaa tatcaaataa
       61 atcatgtgga tgaaattttt gttttacagt tcgaccattc tttaagtcga gagtataatg
      121 tagtgcatca ccccataaaa ttttacaagc caatagataa atcctcccct ttattaaatg
      181 ccgctctttc tgaaaatgaa gagttatcag ctgtatttaa tttttataga attaattctg
      241 gcggttgtat tgaaaggttt tacacaattg aattgcaagg agcacattta tcgaatattc
      301 tgacatgtta tccacactca attacacatg cgggtaatca gccggaagag gtcattgttc
      361 ttaattataa aaatataaca tggaagcacc atatcgcgag tacggaatca tatagttgtt
      421 gggaagaaag gattttttaa atatgaaaag cgatctcact ataaaaaata gatattgtac
      481 aattccacaa gcgaagttcc gtaaatggga tgaaatggac gttttactct ggaagttagg
      541 aaaaaatgat tcg
//
LOCUS       DAFGPF010000322          547 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.331, whole genome shotgun sequence.
ACCESSION   DAFGPF010000322 DAFGPF010000000
VERSION     DAFGPF010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.331"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            94..>547
                     /locus_tag="LSX49_005257"
     CDS             94..>547
                     /locus_tag="LSX49_005257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171490.1"
                     /translation="MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMS
                     IGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
                     ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGL"
BASE COUNT          134 a          113 c          151 g          149 t
ORIGIN      
        1 ctaataactc gcctgcaaaa acgtagaccg catatcgcct tgatgcggct cggaaaaaaa
       61 taataagccc tacaaaatat tgagcgagaa attatggaaa ttgcatcgaa taaaggcgtc
      121 attgcagacg cttcgacccc ggcgggtcgt gctggaatga gtgagagcga gtggcgagaa
      181 gcgatcaaat tcgacagtac tgacactggc tgggtgatta tgagtatcgg gatggcgatt
      241 ggcgcgggga ttgtttttct cccggtgcag gtcggtttga tgggattgtg ggtatttttg
      301 ctctcatcgg tgattggtta cccggcaatg tatctgtttc agcggttgtt tattaatacg
      361 ctggcagaat caccagaatg taaagattac ccgagcgtca tcagcggtta tttaggtaaa
      421 aactggggca tcctgttagg tgcactctat ttcgtaatgc tggtgatttg gatgttcgtc
      481 tattccaccg ccatcaccaa cgatagtgct tcctacctgc ataccttcgg cgtgacggaa
      541 gggttgc
//
LOCUS       DAFGPF010000323          540 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.332, whole genome shotgun sequence.
ACCESSION   DAFGPF010000323 DAFGPF010000000
VERSION     DAFGPF010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.332"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
BASE COUNT          145 a          152 c          119 g          124 t
ORIGIN      
        1 taccattttg cagggagccg gtgcgttact gtctggcaca acaaacgcag cgggtcgctc
       61 tgccccgccg attcctgata atccctcccc tgtaacctac tgcaacagta caaatacact
      121 gacgcctgaa acggtaacca gaatcagcac cagcagtaac gtcagtaaac agagcagacg
      181 atcggtcttc cggtaataac cgaaggggtc gacagcgcca caatacgggc aacaaactgt
      241 attatgagta attgcgttac cacagtccct gcacttcttt ttgcgtatca cgatagctcc
      301 ctcgccacgc cttatccgta accggttttt tacattaaaa aaaacaacgc cgggaattca
      361 atcgtcagtc cggagacgac cgttcgggtt atcacagagt gcctgagaca gtgtcctgcc
      421 ggaggtcact tcagggactc tgcgtatttt ttacgacgtg gctattccgt atgaaccata
      481 cggagattta accatgacct acaaatacaa ccccttctgg cagcaacgta ttcgtgagac
//
LOCUS       DAFGPF010000324          521 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.333, whole genome shotgun sequence.
ACCESSION   DAFGPF010000324 DAFGPF010000000
VERSION     DAFGPF010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.333"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..262)
                     /locus_tag="LSX49_005258"
     CDS             complement(<1..262)
                     /locus_tag="LSX49_005258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL7171491.1"
                     /translation="MYSPYLYARSTELLCLRDLVAKGVSLNGLLPILEPINVNTRNLL
                     TCLNVWNSDIIVILNPYQEDFSSHNNVLTLNQNLSSVLTNKNN"
     gene            complement(284..>521)
                     /locus_tag="LSX49_005259"
     CDS             complement(284..>521)
                     /locus_tag="LSX49_005259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171492.1"
                     /translation="MPNGLVYEYCKEIFMQMPLNIANKYFISAMKKRCNDKVFLDYIY
                     SLPACLRVLGYATPLSRKQKEFIMNLMDVKIKIC"
BASE COUNT          181 a           83 c           71 g          186 t
ORIGIN      
        1 tattattttt atttgttaat acacttgata aattttgatt taaagttaag acgttattgt
       61 gtgaagaaaa atcttcctga taaggattaa ggataacaat tatgtcagaa ttccaaacat
      121 ttaaacatgt taataaattt ctcgtattga cgttaattgg ttctaaaatt ggtagcagac
      181 catttaggct aactcccttc gcaacgaggt ccctaaggca taataactct gtacttctcg
      241 catacaaata tgggctatac ataacttaca actcctgagg atatcaacaa attttaattt
      301 ttacatccat caaattcatg atgaattctt tttgctttct tgataatggt gttgcataac
      361 ctaaaacacg taaacatgct ggaagagaat aaatataatc caaaaaaact ttatcgttac
      421 atcttttttt catagcagag ataaagtatt tatttgctat gtttaatggc atctgcatga
      481 atatctcttt acaatattca taaaccaatc cgttaggcat a
//
LOCUS       DAFGPF010000325          517 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.334, whole genome shotgun sequence.
ACCESSION   DAFGPF010000325 DAFGPF010000000
VERSION     DAFGPF010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.334"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            61..>517
                     /locus_tag="LSX49_005260"
     CDS             61..>517
                     /locus_tag="LSX49_005260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HBL7171493.1"
                     /translation="MDVPVLNFDHSHHKLKIRGLQSPVDVLTFEGREQLSTPFRYDIQ
                     FTSTDKAIAPESVLMQDGAFSLTAPPVQGMPVQTALRTLHGVITSFKHLSSSQDEARY
                     EVRLEPRMALLTRSRQNAIYQNLTVPQIVEKILRERHQMRGQDFVFNLKS"
BASE COUNT          132 a          155 c          128 g          102 t
ORIGIN      
        1 tccgaacaag aaataacggc tcgttattct ttgttagata aatgaaggag tacaaagaaa
       61 atggatgttc ctgttctgaa tttcgaccac tcacaccaca agctcaaaat tcgcggcctg
      121 caaagtccgg tggatgtgct gaccttcgaa ggccgcgaac aactgagtac cccgttccgc
      181 tacgacattc agtttaccag taccgataaa gccatcgcgc cggagtcggt gctgatgcag
      241 gacggcgcat tcagcctgac ggcaccaccg gtacagggaa tgccggtgca gactgccctg
      301 cgcaccctgc acggcgtcat taccagcttt aaacacctct cctcgtcaca ggacgaagcc
      361 cgttacgaag tgcgccttga accccgtatg gcgctgctta cccgcagccg ccagaacgcc
      421 atctaccaga atctgacggt gccgcaaatc gtcgaaaaaa tcctgcgcga gcggcaccag
      481 atgcgcggtc aggacttcgt gtttaacctc aaaagcg
//
LOCUS       DAFGPF010000326          491 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.335, whole genome shotgun sequence.
ACCESSION   DAFGPF010000326 DAFGPF010000000
VERSION     DAFGPF010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.335"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>491
                     /locus_tag="LSX49_005261"
     CDS             <1..>491
                     /locus_tag="LSX49_005261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL7171494.1"
                     /translation="WERKGGKTALKAIEYVRQLYGIDVRLKICGCTPNQKILPTWVEL
                     IDKVDKNNVDEYQKFIDVLSNADILLLPTIAECYGMVFCEAAAFGLPVVATDTGGVSS
                     IVINERTGILIKDPLDYKHFGNAIHKIISSVETYQNYSQNARIRYNNILHWDNWAKKI
                     IEI"
BASE COUNT          175 a           65 c          102 g          149 t
ORIGIN      
        1 tgggaaagaa aaggtgggaa aacagccttg aaagcaattg aatatgtaag gcagttatat
       61 gggatcgatg ttagactaaa aatttgtgga tgtactccga atcaaaagat tttacctact
      121 tgggttgaat taattgataa agtagataaa aataacgttg acgaatatca gaaattcatc
      181 gatgtgttat ctaacgctga tatacttctt ttaccaacca ttgctgaatg ttatggaatg
      241 gtattttgtg aagctgctgc ttttggattg cctgttgtcg ctacagatac aggtggagtc
      301 agttctatag ttatcaacga aaggacgggg atattaatta aagacccgtt agactataag
      361 cactttggaa atgcaattca taaaataatt agttccgtag agacttatca aaactactcc
      421 caaaacgcaa gaattagata taataatata ttgcattggg acaattgggc taaaaagata
      481 attgagatta t
//
LOCUS       DAFGPF010000327          489 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.336, whole genome shotgun sequence.
ACCESSION   DAFGPF010000327 DAFGPF010000000
VERSION     DAFGPF010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.336"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..420)
                     /locus_tag="LSX49_005262"
     CDS             complement(<1..420)
                     /locus_tag="LSX49_005262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000635307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL7171495.1"
                     /translation="MIVIDFFCGCGGASEGLRQAGFDIELGLDIDQQASETFKANFPD
                     AKFIQDDIRKIEPQDISDIIDIKAKRPLLLSACAPCQPFSQQNKNKTSDDSRRNLLNE
                     THRFIRELLPEYIMLENVPGMQKIDEEKEGPFQEFIKL"
BASE COUNT          154 a           88 c           77 g          170 t
ORIGIN      
        1 tagcttaata aactcctgaa atgggccttc tttttcttca tcaatttttt gcattccagg
       61 aacattttca agcataatat attcaggaag aagttctcta ataaaacgat gagtttcatt
      121 tagtagattt ctccttgagt cgtcactagt tttattttta ttctgttgcg aaaatggttg
      181 acatggtgca catgcactca gtaacaaagg ccgtttagct ttaatatcaa tgatgtcgga
      241 gatatcttga ggttcgattt tcctaatatc atcttggatg aattttgcat cagggaaatt
      301 agctttaaat gtttctgatg cttgttggtc aatatctaat ccaagctcga tatcaaagcc
      361 agcctgacgt agcccttcac tggctccacc acagccacaa aaaaaatcta taactatcaa
      421 tttgatacct tctttgaact aaataaaaca actcgaataa gttgatattt taaataaaaa
      481 taattggta
//
LOCUS       DAFGPF010000328          487 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.337, whole genome shotgun sequence.
ACCESSION   DAFGPF010000328 DAFGPF010000000
VERSION     DAFGPF010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.337"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..>487)
                     /gene="rfaY"
                     /locus_tag="LSX49_005263"
     CDS             complement(<1..>487)
                     /gene="rfaY"
                     /locus_tag="LSX49_005263"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HBL7171496.1"
                     /translation="DDTKVMLIDTDYGKLILKVFSPKVKRNERFFKSLLKGDYYERLF
                     VQTQKVRNEGLNTLNDFYLLAERKTLRFVHTYIMIIEYIDGIELCDMPDIDDSLKNKI
                     QQSINALHKHGMVSGDPHRGNFIIKNGEVRIIDLSGKRASAQRKAKDRIDLERHYGIK
                     NE"
BASE COUNT          156 a           94 c           77 g          160 t
ORIGIN      
        1 tctcattttt aataccgtaa tgacgctcta agtcaatgcg atctttcgct ttacgctgcg
       61 ctgaagcacg ttttccagag agatcaataa ttcggacctc accatttttt ataatgaagt
      121 taccacgatg agggtcgcca gaaaccatgc catgtttatg caaggcatta attgattgtt
      181 gaattttatt ttttagcgaa tcatcaatat cgggcatatc acataactct ataccatcaa
      241 tatactcgat gatcatgata taagtatgga caaatcgtaa ggttttccgt tcagccaata
      301 aataaaaatc attgagtgta tttaaccctt catttcgtac tttttgagtt tgcacaaaaa
      361 ggcgttcgta ataatcacct tttaacagag acttaaagaa acgttcgtta cgcttaactt
      421 tcggagaaaa aaccttaaga atcaatttac cgtaatcggt atcaataagc ataacttttg
      481 tatcatc
//
LOCUS       DAFGPF010000329          486 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.338, whole genome shotgun sequence.
ACCESSION   DAFGPF010000329 DAFGPF010000000
VERSION     DAFGPF010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.338"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
BASE COUNT          147 a          114 c           91 g          134 t
ORIGIN      
        1 catgcaattt gataagttat gacgaattct caccatccag ttactacctg tacatactaa
       61 tcaaaaaaaa cgagtacgca agatacgaaa gtacttttct tgttcaccag ttagcttacc
      121 ttgatcctca ccagcgactg gaagataggt agcagtatat gtggaaacct tcccctagct
      181 aggtctacaa acgtagtttg ggcatttagg ctccacgatt cacggtttga cacggcctga
      241 tatctgcaca ttcgttttga tatgcagcaa tcgtgaaaaa ggaaaatata cgctcgacag
      301 accaaaacgg cactacaccg cacccgcctg cggttttcat atcactaaaa attttcagcc
      361 tggatttttt acaaacgata ccgccagtcc gtgccagtcc tcgagatgta ctgcgataca
      421 ggaactgaaa agaatgaaaa gaaattcatt ttttttcagt tttactgtcc gtcgaatcta
      481 tggcct
//
LOCUS       DAFGPF010000330          484 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.339, whole genome shotgun sequence.
ACCESSION   DAFGPF010000330 DAFGPF010000000
VERSION     DAFGPF010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.339"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..484
                     /locus_tag="LSX49_005264"
     rRNA            <1..484
                     /locus_tag="LSX49_005264"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          119 a          119 c          143 g          103 t
ORIGIN      
        1 gctgtcgtca gctcgtgttg tgaaatgttg ggttaagtcc cgcaacgagc gcaaccctta
       61 tcctttgttg ccagcggtcc ggccgggaac tcaaaggaga ctgccagtga taaactggag
      121 gaaggtgggg atgacgtcaa gtcatcatgg cccttacgac cagggctaca cacgtgctac
      181 aatggcgcat acaaagagaa gcgacctcgc gagagcaagc ggacctcata aagtgcgtcg
      241 tagtccggat tggagtctgc aactcgactc catgaagtcg gaatcgctag taatcgtgga
      301 tcagaatgcc acggtgaata cgttcccggg ccttgtacac accgcccgtc acaccatggg
      361 agtgggttgc aaaagaagta ggtagcttaa ccttcgggag ggcgcttacc actttgtgat
      421 tcatgactgg ggtgaagtcg taacaaggta accgtagggg aacctgcggt tggatcacct
      481 cctt
//
LOCUS       DAFGPF010000331          481 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.340, whole genome shotgun sequence.
ACCESSION   DAFGPF010000331 DAFGPF010000000
VERSION     DAFGPF010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.340"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..>481)
                     /locus_tag="LSX49_005265"
     CDS             complement(<1..>481)
                     /locus_tag="LSX49_005265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyl transferase family 1"
                     /protein_id="HBL7171497.1"
                     /translation="DDGSVCGKVIEWFFFEEKSILLNKNKNKNILFYIGPFIPNGILS
                     SWLNLISVIDRDKYNISLVVDPKSIHGFQERFEQFKRVSPDIQVIGTCGNMLYNIEEK
                     WLNDKLNNQFTLASKEMYDILDHAYQREFLRLFGYSHIDHLIHFEGYNQSWVIRFANA
                     "
BASE COUNT          173 a           85 c           63 g          160 t
ORIGIN      
        1 agcattagca aaccggataa cccaagattg attataacct tcaaaatgga ttagatgatc
       61 aatatgacta tagccaaaga gccttaaaaa ctctcgttgg taagcatgat caagaatatc
      121 atacatttcc ttacttgcca gggtgaattg attatttaat ttatcattaa gccatttctc
      181 ttcaatatta taaagcatgt ttccacaagt tccaatgact tgaatatctg gagagactct
      241 cttaaactgc tcgaaccgtt cttgaaaacc atgaattgat tttgggtcaa caaccaaaga
      301 aatattatat ttatcacgat caattaccga tataagattt agccatgatg acaatatacc
      361 atttggaata aatggaccaa tataaaaaag tatattttta tttttgtttt tattaagcaa
      421 tatggatttt tcttcaaaga agaaccattc aattactttt ccacatacac ttccatcatc
      481 a
//
LOCUS       DAFGPF010000332          477 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.341, whole genome shotgun sequence.
ACCESSION   DAFGPF010000332 DAFGPF010000000
VERSION     DAFGPF010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.341"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>477
                     /locus_tag="LSX49_005266"
     CDS             <1..>477
                     /locus_tag="LSX49_005266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ribonuclease H"
                     /protein_id="HBL7171498.1"
                     /translation="IKNTRAMAHSLYFEGSYTLIEKDGKHRKGTLSELEGRFAFIDML
                     DKYNNVEAKKNARPERYVVKGFGLDFKQRLNSREKAYSKFLYYKNFYGNEQITILTEG
                     KTDPVYLKCAIDSLFLDYPQLVREEKNTKNRVLKVNLFKTNDKKKYFLDLSGGAAD"
BASE COUNT          179 a           61 c          100 g          137 t
ORIGIN      
        1 tataaagaat acaagagcga tggcgcattc tttatacttt gaaggttcgt atacacttat
       61 tgagaaagat ggaaaacata gaaagggcac ccttagtgaa ttagaagggc gatttgcatt
      121 tatcgatatg cttgataaat ataataatgt ggaagcaaag aaaaatgcgc gtcctgagag
      181 atatgtggtt aaaggatttg ggttggattt taagcagaga cttaactcca gagagaaagc
      241 atacagcaaa ttcctatact ataaaaattt ctatggaaat gagcaaataa caatcttaac
      301 agaagggaaa actgacccgg tttatcttaa gtgtgcaatt gattctttgt ttttggatta
      361 ccctcagtta gttagagagg aaaaaaacac aaagaataga gtgttaaaag ttaatttatt
      421 taaaaccaat gacaagaaaa aatattttct cgatttgtct ggtggagctg cagacta
//
LOCUS       DAFGPF010000333          467 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.342, whole genome shotgun sequence.
ACCESSION   DAFGPF010000333 DAFGPF010000000
VERSION     DAFGPF010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.342"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
BASE COUNT          160 a           83 c           86 g          138 t
ORIGIN      
        1 ggtattcctt tacaacaaag gtacgctgat atcaacatgg ccgctgacag ccaagttgat
       61 atcatataat acacgacata atctgtagtc agggaggata gactctttac tgactacaga
      121 ttatgtcgtg ttccgtgctc atttcctcaa aaaaatacaa gaaaagaatt agtattctaa
      181 caaaaagtga aataaattgt atcaaactcc ctcttttaat cctgttgagt aaatcagctt
      241 ttgcaatagg attgaaagag tgtaagtgga atctcttccg gatactcgtt accaccgtgg
      301 ctagaatatc tacggctgcg ggccagtaat agattaagtg ataacagctg tctggaaatg
      361 taggggcgta tccactaatc ataatcattg tgagataaat attacggggc attttataat
      421 gaataaaata tactctctaa aatattgtca tattaccaat accatga
//
LOCUS       DAFGPF010000334          463 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.344, whole genome shotgun sequence.
ACCESSION   DAFGPF010000334 DAFGPF010000000
VERSION     DAFGPF010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.344"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(<1..212)
                     /locus_tag="LSX49_005267"
     CDS             complement(<1..212)
                     /locus_tag="LSX49_005267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001408654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HBL7171499.1"
                     /translation="MDEIRNYSLSDKNNSQPICFFLGRDKGRLQIINELADRLTTLGC
                     KLDFNVVKDKTSSPTSKYLIEKQISY"
BASE COUNT          158 a           67 c           51 g          187 t
ORIGIN      
        1 tcatacgata tttgtttttc aatcaaatac tttgaagtcg gagatgatgt tttatctttg
       61 acaacattaa aatctaactt acatcctagt gttgttaatc tatcggctaa ttcattaatt
      121 atttgaagac gtcctttatc acgaccaaga aaaaaacata ttggctgact gttatttttg
      181 tcagataaac tataatttct aatttcatcc attcctatag gaaaaaattg ttctattgcc
      241 ttgatctttt cattccctat aaatctatgc tcaaaatcat agataatatc aaaataatta
      301 gcgttatcaa aaataaaatt ttcactgaca gtatttctta gaagtaatac tttatgacaa
      361 ttaatatttt ttaatatttg cttgttaata cttttattaa tgacactgtc attaaatata
      421 atgatatcat ccttttttac agcatttagg tgatgtttga taa
//
LOCUS       DAFGPF010000335          456 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.346, whole genome shotgun sequence.
ACCESSION   DAFGPF010000335 DAFGPF010000000
VERSION     DAFGPF010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.346"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            352..456
                     /locus_tag="LSX49_005268"
                     /pseudo
     CDS             352..456
                     /locus_tag="LSX49_005268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453335.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
BASE COUNT          128 a           98 c          126 g          104 t
ORIGIN      
        1 aatacatgag ttcatatatg tgaaataaac actgtgagtg cgatcagtgg gcatgagaac
       61 gcagtagcag cagattgcgt tgtacccaca gggctatctc tgatagctgg cgtataacct
      121 gcgtatataa aacgtacctg caacacacgt gaacagagtg cattaagcat ccgtctgagc
      181 ggtaaacgta tccgacctgg tgagtgacag tctgagagac cggttaagtg gtggcacggg
      241 agtaatgagt ttggggaggg taccagaatg ccaggctggt gcggtatgct gacagcatcc
      301 tgttaaccgc agcataaagt aatgagaggc taatggaagt taaaaccaca gcagttccgt
      361 cgttgttcat cccgggagac gctggaaaaa gtgatttccc acacgcgtta taaacttacc
      421 cctgcggagc tggaagcctt taactctgcc gttgac
//
LOCUS       DAFGPF010000336          448 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.347, whole genome shotgun sequence.
ACCESSION   DAFGPF010000336 DAFGPF010000000
VERSION     DAFGPF010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.347"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(111..>448)
                     /locus_tag="LSX49_005269"
     CDS             complement(111..>448)
                     /locus_tag="LSX49_005269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL7171500.1"
                     /translation="MNEEYFLYYEELDICLRAKAKNFKLGICSESLVYHKIGASTDGG
                     KSMMADLCSIKNRLVITERFYPQYYWTVWLSLFVVAFNRARRGEFNKMKRCLNVMFNF
                     KRNKGSKCH"
BASE COUNT          153 a           92 c           52 g          151 t
ORIGIN      
        1 actggatgta gatagtggat cataagcaga taaaaaagcc actttcatta aatacccttt
       61 aataacatat caaactatag atttattaac accatgatta agtgcatatt ctaatggcat
      121 ttgctacctt tgtttcgttt gaagttaaac ataacattca aacatctttt catcttatta
      181 aactcacctc ttctagcacg gttaaatgct acaacaaaaa gtgacaacca taccgtccaa
      241 taatattggg gataaaacct ttctgtaatg accagcctat tttttattga gcaaagatca
      301 gccatcatgc tctttccccc atcagtactt gcacctattt tatgataaac caaactttct
      361 gagcaaatac ctaatttaaa gttctttgct tttgctctga ggcaaatatc taactcttca
      421 tagtataaaa aatattcttc attcatca
//
LOCUS       DAFGPF010000337          443 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.denovo.348, whole genome shotgun sequence.
ACCESSION   DAFGPF010000337 DAFGPF010000000
VERSION     DAFGPF010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.denovo.348"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..>443
                     /locus_tag="LSX49_005270"
     CDS             <1..>443
                     /locus_tag="LSX49_005270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBL7171501.1"
                     /translation="ITNAERHRDKNIVFNIDIENFFPSFNFGRVRGYFIANQNFKLHP
                     NVATIIAQIACLDGSLPQGSPCSPVITNLICRILDFRLSKLAVTYGCSYSRYADDITF
                     STNKKNIPDALVSNEKENEPGKILVEEIHRAGFTLNHNKNRVSRC"
BASE COUNT          150 a           77 c           81 g          135 t
ORIGIN      
        1 aattacaaat gctgagaggc atcgagataa aaatattgta tttaatattg atattgagaa
       61 tttcttccca tcctttaatt ttggtcgcgt gcgaggatat tttattgcaa accaaaattt
      121 caagttacat ccaaatgttg caaccattat tgcgcagata gcctgcctgg atggatcgct
      181 tccgcaagga agcccttgtt ctccagtaat aactaatctt atttgtagga ttttagattt
      241 cagattatca aagctagcag tcacatatgg ttgtagttac agccgctatg cagatgacat
      301 tacgttttca acaaacaaaa aaaacatccc tgatgcatta gtttctaatg agaaagaaaa
      361 cgaaccaggt aagatattgg tagaagaaat tcatcgtgca ggcttcactt taaaccataa
      421 taaaaacaga gtgtctaggt gta
//
LOCUS       DAFGPF010000338         6121 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.197, whole genome shotgun sequence.
ACCESSION   DAFGPF010000338 DAFGPF010000000
VERSION     DAFGPF010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6121
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.197"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..81
                     /locus_tag="LSX49_005271"
     CDS             <1..81
                     /locus_tag="LSX49_005271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL7171502.1"
                     /translation="QTVKQQRVECRGTWFTNFYMRYKPQH"
     gene            271..1410
                     /locus_tag="LSX49_005272"
     CDS             271..1410
                     /locus_tag="LSX49_005272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBL7171503.1"
                     /translation="MGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVG
                     MPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILARKYNADKFEKRLSD
                     LDDVAEESWLEENLPSAFAQHPWHNSLGSIGGGNHFAELQQIDQIIDAELFARAGLDA
                     QHLQLLVHSGSRGLGQSILQRHIASFSHHGLPEGSDDALRYIAEHDDALAFARINRQL
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWLVKPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVLAGLIIPVARLRPVLTLKNSGGKKG"
     gene            1407..2021
                     /locus_tag="LSX49_005273"
     CDS             1407..2021
                     /locus_tag="LSX49_005273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HBL7171504.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEATRQDVAVTVLETET
                     GRYSDTLRSALISLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAALKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     gene            complement(2077..3534)
                     /gene="pepD"
                     /locus_tag="LSX49_005274"
     CDS             complement(2077..3534)
                     /gene="pepD"
                     /locus_tag="LSX49_005274"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HBL7171505.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFNLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
                     KSLVDTYQEILKNELAEKEKNLALLLDSVANDKAALTATSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            3795..4253
                     /gene="gpt"
                     /locus_tag="LSX49_005275"
     CDS             3795..4253
                     /gene="gpt"
                     /locus_tag="LSX49_005275"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL7171506.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            4345..5589
                     /gene="frsA"
                     /locus_tag="LSX49_005276"
     CDS             4345..5589
                     /gene="frsA"
                     /locus_tag="LSX49_005276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HBL7171507.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFSHGAQLPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILEVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     ALRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            5647..6048
                     /gene="crl"
                     /locus_tag="LSX49_005277"
     CDS             5647..6048
                     /gene="crl"
                     /locus_tag="LSX49_005277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HBL7171508.1"
                     /translation="MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLRE
                     FHEKLRELLATLNLKLEPADDFRDEPVKLTA"
BASE COUNT         1480 a         1500 c         1630 g         1511 t
ORIGIN      
        1 cagacagtta agcagcagcg cgttgaatgc cggggaacgt ggtttactaa tttttatatg
       61 cgatataaac cgcaacatta aatccagctt gcaatgaaaa taacgcccgt ctagtatgtg
      121 cgcgttttct tattccacaa actgcaagga ggtaaatcat gacaaatcct ttatcaatga
      181 ctctttgcag acctttccag gattaattct tttttcttgc cctggattcg tctgccattt
      241 cctgattttt attcataaat ggaatggtac atgggcaaat atattcgtcc cttatccgat
      301 gcggtattta ccatcgcatc tgatgacctg tggatcgaga gtttagcgat ccaacaatta
      361 cacaccacgg caaatttacc caacatgcag cgcgttgtgg ggatgccaga tttacatccc
      421 ggacgcggct acccgattgg cgcagcgttc ttctctgttg gtcgttttta cccggcactg
      481 gtcggcaatg atatcggctg cggcatggcg ctatggcaaa cagatattct cgctcgcaaa
      541 tacaacgccg ataagtttga aaagcgatta tcagatctgg atgacgttgc tgaagaaagc
      601 tggctggagg aaaacctgcc gtcagcattt gcacagcatc cgtggcacaa ctcgcttggc
      661 tccatcggtg gcggtaacca cttcgcagaa ctgcaacaga ttgatcaaat tatcgacgcg
      721 gaactgtttg cacgggctgg tctggatgcg cagcatctgc aactactggt tcatagcggc
      781 tcgaggggat tggggcagtc tattttacag cggcatattg cctcgttttc gcatcatggt
      841 ttgcctgaag gcagtgacga cgcgctacgg tatattgcgg aacatgacga tgcgctggcg
      901 tttgcgcgta ttaatcgcca gctgatcgct ttgcgcataa tgcaacaagt taaggccacc
      961 ggaagtccgg ttctggatgt ggcgcataac tttgttagcg cgtgccaaat cggcgatcaa
     1021 cagggctggt tgcatcgtaa aggcgccacg ccggatgaca acggtctggt gattattccc
     1081 ggttcacgcg gcgattactc ctggctggtt aaacctgttg cgaacgaaaa aacgctccac
     1141 tcgctggcgc atggggcggg gcgtaaatgg gggcgcaccg agtgtaaagg gcgtctggca
     1201 gcgaaataca cggcgacgca actctcgcgg actgaacttg gcagtcgggt aatttgtcgc
     1261 gataaacaac tcatctttga agaagcgcca caagcctata aatcggctga aagcgtggtg
     1321 caatgtctgg tgctggctgg gttaattatt cctgtcgcgc gactgcgccc ggtgctgacg
     1381 ctcaaaaaca gtggagggaa aaaaggatga tcttgctaca actctcctct gctcaggggc
     1441 cggaagaatg ttgtctcgca gtgaaaaaag cactggacag gctgattaaa gaagctaccc
     1501 gacaggacgt cgcggtaacg gtgctggaaa cagaaacggg tcgctactct gacacactgc
     1561 gttcggcgct gatttctctg gatggcgata acgcatgggc tctaagcgaa agctggtgcg
     1621 gcactattca gtggatttgt ccgagtccgt atcggcctca tcatgggcgc aaaaactggt
     1681 ttctgggcat tgggcgtttt accgctgatg agcaggaaca atcggatgca atccgttatg
     1741 agacgctgcg ttcgtcgggg ccgggcggtc aacatgtcaa taaaaccgac tcggcggtac
     1801 gcgccacgca tctggcatcc ggtattagcg tgaaggttca gtcagagcgc agtcagcatg
     1861 ctaacaaacg gctggcgcga ttactgattg cctggaagct ggaacaacag caacaggaaa
     1921 atagcgcggc gctgaaatcg cagcggcgaa tgttccatca ccagattgaa cgtggcaacc
     1981 cgcgacgaac gttcacaggg atggctttta tcgaaggata atgaaggatg aaactgccgg
     2041 aaggcgttaa acgccatccg gcagcaaatc aaataattac ttcgccggaa tttctttcag
     2101 cagttcagtc agcagtgtcc agtaatggcc aacgctttcg atatgaactt gctcatccgg
     2161 ggagtgtgga ccggtgatgg ttggcccgat agacaccatg tccatttccg gatacggttt
     2221 tttgaacaga ccacattcca ggcccgcgtg gataatctgg atgttcggcg tcttgttgaa
     2281 cagacgctga taggtttcac gtaccagatg cattaccgga gagttagcgt ccggctgcca
     2341 gccaggatat gcgccttttg cttcggtttt cgcacctgcc agtttaccca gcgaatccag
     2401 catgctcact acgtagtctt taccgctgtc gatcagagaa cggatcaggc agtgaatttc
     2461 tacgttattg tcggtcatgg tcaccacacc gacgttcagg gaggtttcaa ccacgccttt
     2521 ggctacatcg gaattacgga taactccgtt cggggtggcg ttcagcagac gaataaaggt
     2581 atcgcgagat gtcgccgtta atgcagcttt gtcgttcgct acggagtcca gcagcaatgc
     2641 cagattcttc tctttttctg ccagttcgtt tttcaggatc tcctgatagg tatccaccag
     2701 agatttcagg gcgtcgactt tatcagctgc gacagcaatg gtcgcaaagg cttcacgcgg
     2761 gatggcgtta cgcagtgtgc cgccgttgaa atcaataaga cgcaggtcca gttcttctgc
     2821 atgacccgcc aggaagcgca ccagcagttt gttggcatta cccaggccaa cgtggatttc
     2881 accgccggag tgaccgcctt tcagaccttt taaggttaaa ttgaaggttt caaaaccagc
     2941 tggaaccgct tcacgatcta aatgcaggtt ggaggtgaag tcgatacccc ccgcacatcc
     3001 catgtagatt tcaccttctt cttcggagtc ggtgttaatc agaatatcag cctgcaacca
     3061 gttgctctgt aagccgaacg caccgtccat accggcttct tcagtcatgg tcagcagcac
     3121 ttccagcggg ccgtgaacca cgttttcgtc agccagaacc gccagtgcgg aggccatacc
     3181 aatgccgtta tccgcaccca gcgtggtgcc gcgcgcttta acccattcgc catcaatata
     3241 aggctggata ggatctttag tgaagtcatg cacggtgtcg ttattttttt gcggcaccat
     3301 atcgaggtgg gcctgcaaga cgaccggttt acgattttcc atacctgcgg tagcaggttt
     3361 acgaatcagg atattaccta cctgatcgcg ttcgacatgg aaacctttct cttttgccca
     3421 accaacaatg tattcagcga gttgctcttc atgataggac gggtgaggaa tagaacagat
     3481 tttggcaaaa atatcccaca gcggctgtgg agataattga gacagttcag acacgttaag
     3541 tctccttgtc gatcacccgc aaaacagtat tgcaggtcac agggttagca gaaaatgttg
     3601 tcaacacaag acaggcttgc gagatatgtt tgagaatacc actttatccc gcgtcaggga
     3661 gaggcagtgc gtaaaaagac gcggactcat gtgaaatact ggtttttagt gcgccagatc
     3721 tctataatct cgcgcaacct attttcccct cgaacacttt ttaagccgta gataaacagg
     3781 ctgggacact tcacatgagc gaaaaataca tcgtcacctg ggacatgttg cagatccatg
     3841 cacgtaaact cgcaagccga ctgatgcctt ctgaacaatg gaaaggcatt attgccgtaa
     3901 gccgtggcgg tctggtaccg ggtgcgttac tggcgcgtga actgggtatt cgtcatgtcg
     3961 ataccgtttg tatttccagc tacgatcacg acaaccagcg cgagcttaaa gtgctgaaac
     4021 gcgcagaagg cgatggcgaa ggcttcatcg ttattgatga cctggtagat accggtggta
     4081 ctgcggttgc gattcgtgaa atgtatccaa aagcgcactt tgtcaccatc ttcgcaaaac
     4141 cggctggtcg tccgctggtt gatgattatg ttgttgatat cccgcaaaat acctggatcg
     4201 aacagccgtg ggatatgggc gtcgtattcg tcccgccaat ctccggtcgc taatcttttc
     4261 aacgcctggc actgccgggc gttgttcttt ttaacttcag gcgggttaca atagtttcca
     4321 gtaagtattc tggaggctgc atctatgaca caggcaaacc tgagcgaaac cctgttcaaa
     4381 ccccgcttta aacatcctga aacctcgacg ctagtccgcc gctttagtca cggcgcacaa
     4441 ctgcctgtgc agtcggccct tgatggtaaa accatccctc actggtatcg catgattaac
     4501 cgtctgatgt ggatctggcg cggcattgac ccccgtgaaa tcctcgaagt ccaggcgcgt
     4561 attgtgatga gcgatgccga acgtaccgac gatgatttat acgatacggt gattggctac
     4621 cgcggcggca actggattta tgagtgggct acccaggcga tggtgtggca acaaaaagcc
     4681 tgtgcggaag aagatccgca actcagcggt cgacactggc tgcatgcggc tacgttgtac
     4741 aacattgctg cctatcctca tctgaaagga gatgacctgg ccgagcaagc gcaggctttg
     4801 tcaaaccgcg cctatgaaga ggccgctcag cgtctgccgg gcacgatgcg gcagatggag
     4861 tttaccgtac ccggcggtgc gcccatcacc ggctttttgc atatgccgaa aggcgatggc
     4921 ccgttcccga cagtattaat gtgtggtggt ctggatgcga tgcagacaga ctattacagc
     4981 ctgtatgaac gttattttgc gctgcgcggc attgcgatgc tgactattga tatgccgtcg
     5041 gtgggctttt cttcaaaatg gaagctcacc caggactcca gcctgttgca tcagcacgtt
     5101 ttaaaggcgt tgcctaacgt accgtgggtg gatcacactc gcgtcgcggc ctttggtttc
     5161 cgtttcggcg ctaacgttgc cgtacgtctg gcataccttg aatcgccgcg tctgaaagcg
     5221 gttgcctgtc ttggtccggt agttcatacc ctgttgagtg attttaagtg ccagcaacag
     5281 gtgccggaaa tgtatcttga cgttctggcg agtcgtttgg ggatgcatga tgcttctgac
     5341 gaagcgttgc gcgtggagct gaatcgctat tcattaaaag tgcaagggtt gctgggacgt
     5401 cgctgcccaa cgccaatgtt atcaggctac tggaagaacg atccgttcag cccggaagag
     5461 gactcacgct taatcacgtc gtcatctgct gacggtaaat tattagagat cccatttaac
     5521 ccggtgtatc ggaattttga caaaggcctt caggaaatca cagactggat cgaaaaacgt
     5581 ttgtgttaaa aatttgctaa attttaccaa tttggtaaaa cagttgcatc acaacaggag
     5641 attgcaatga cgttaccgag tggacacccg aagagcagat tagtcaaaaa atttaccgca
     5701 ctaggcccgt atattcgtga aggtaagtgc gaagataatc gattcttttt cgattgtctg
     5761 gctgtatgcg tcaacgtgaa accggcaccg gaagtgcgtg agttctgggg ctggtggatg
     5821 gaactggaag cgcaggaatc ccgttttacc tacagttacc agtttggtct gttcgataaa
     5881 gcaggcgact ggacgagtgt tcagataaaa gatgccgaag tggttgaacg actggagcac
     5941 accctgcgtg aatttcacga gaagctgcgt gagctgctgg cgacgctgaa tctgaagctg
     6001 gaaccggcag atgattttcg tgatgaaccg gtgaagttaa cggcgtgaat gaaatgtgcc
     6061 ggatgcatca catccggcaa tatccattaa aactgatagg tcatgccaac cgcgacaata
     6121 t
//
LOCUS       DAFGPF010000339         5003 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.210, whole genome shotgun sequence.
ACCESSION   DAFGPF010000339 DAFGPF010000000
VERSION     DAFGPF010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5003
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.210"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            complement(41..154)
                     /locus_tag="LSX49_005278"
                     /pseudo
     CDS             complement(41..154)
                     /locus_tag="LSX49_005278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454193.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(357..1370)
                     /gene="intI1"
                     /locus_tag="LSX49_005279"
     CDS             complement(357..1370)
                     /gene="intI1"
                     /locus_tag="LSX49_005279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="HBL7171509.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     gene            1528..2001
                     /locus_tag="LSX49_005280"
     CDS             1528..2001
                     /locus_tag="LSX49_005280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HBL7171510.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
     gene            2132..2920
                     /locus_tag="LSX49_005281"
     CDS             2132..2920
                     /locus_tag="LSX49_005281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HBL7171511.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
     gene            3126..3473
                     /locus_tag="LSX49_005282"
     CDS             3126..3473
                     /locus_tag="LSX49_005282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HBL7171512.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     gene            3467..4306
                     /gene="sul1"
                     /locus_tag="LSX49_005283"
     CDS             3467..4306
                     /gene="sul1"
                     /locus_tag="LSX49_005283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /protein_id="HBL7171513.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     gene            4434..4637
                     /locus_tag="LSX49_005284"
     CDS             4434..4637
                     /locus_tag="LSX49_005284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL7171514.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLGIASENGK"
     gene            4793..>5003
                     /locus_tag="LSX49_005285"
     CDS             4793..>5003
                     /locus_tag="LSX49_005285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBL7171515.1"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRR
                     RWLSERSYADLVALCQFLPGPASSQV"
BASE COUNT         1083 a         1388 c         1403 g         1129 t
ORIGIN      
        1 gatgataagt ttatcaccac cgactatttg caacagtgcc ggccgccgcc ggcatcggcc
       61 tggcgaacag gaaaccctgc accgtgtcgc aacccgcctg ccgcaaccac gcaaggcagt
      121 cgggtgtttc cacaccctcg gctaccacct ccattgtcgt tttcagaaga cggctgcact
      181 gaacgtcaga agccgactgc actatagcag cggaggggtt ggatccatca ggcaacgacg
      241 ggctgctgcc ggccatcagc ggacgcaggg aggactttcc gcaaccggcc gttcgatgcg
      301 gcaccgatgg ccttcgcgca ggggtagtga atccgccagg attgacttgc gctgccctac
      361 ctctcactag tgaggggcgg cagcgcatca agcggtgagc gcactccggc accgccaact
      421 ttcagcacat gcgtgtaaat catcgtcgta gagacgtcgg aatggccgag cagatcctgc
      481 acggttcgaa tgtcgtaacc gctgcggagc aaggccgtcg cgaacgagtg gcggagggtg
      541 tgcggtgtgg cgggcttcgt gatgcctgct tgttctacgg cacgtttgaa ggcgcgctga
      601 aaggtctggt catacatgtg atggcgacgc acgacaccgc tccgtggatc ggtcgaatgc
      661 gtgtgctgcg caaaaaccca gaaccacggc caggaatgcc cggcgcgcgg atacttccgc
      721 tcaagggcgt cgggaagcgc aacgccgctg cggccctcgg cctggtcctt cagccaccat
      781 gcccgtgcac gcgacagctg ctcgcgcagg ctgggtgcca agctctcggg taacatcaag
      841 gcccgatcct tggagccctt gccctcccgc acgatgatcg tgccgtgatc gaaatccaga
      901 tccttgaccc gcagttgcaa accctcactg atccgcatgc ccgttccata cagaagctgg
      961 gcgaacaaac gatgctcgcc ttccagaaaa ccgaggatgc gaaccacttc atccggggtc
     1021 agcaccaccg gcaagcgccg cgacggccga ggtcttccga tctcctgaag ccagggcaga
     1081 tccgtgcaca gcaccttgcc gtagaagaac agcaaggccg ccaatgcctg acgatgcgtg
     1141 gagaccgaaa ccttgcgctc gttcgccagc caggacagaa atgcctcgac ttcgctgctg
     1201 cccaaggttg ccgggtgacg cacaccgtgg aaacggatga aggcacgaac ccagtggaca
     1261 taagcctgtt cggttcgtaa actgtaatgc aagtagcgta tgcgctcacg caactggtcc
     1321 agaaccttga ccgaacgcag cggtggtaac ggcgcagtgg cggttttcat ggcttgttat
     1381 gactgttttt ttgtacagtc tatgcctcgg gcatccaagc agcaagcgcg ttacgccgtg
     1441 ggtcgatgtt tgatgttatg gagcagcaac gatgttacgc agcagggcag tcgccctaaa
     1501 acaaagttag ccattaaggg agttaaattg aaaatatcat tgatttctgc agtgtcagaa
     1561 aatggcgtaa tcggtagtgg tcctgatatc ccgtggtcag taaaaggtga gcaactactc
     1621 tttaaagcgc tcacatataa tcaatggctc cttgtcggaa gaaaaacatt tgactctatg
     1681 ggtgttcttc caaatcgcaa atatgcagta gtgtcaaaga acggaatttc aagctcaaat
     1741 gaaaacgtcc tagtttttcc ttcaatagaa aatgctttga aagagctatc aaaagttaca
     1801 gatcatgtat atgtctctgg cgggggtcaa atctataata gccttattga aaaagcagat
     1861 ataattcatt tgtctactgt tcacgttgaa gtcgaaggtg atatcaaatt ccctataatg
     1921 cctgagaatt tcaatttggt ttttgaacag ttttttatgt ctaatataaa ttatacatac
     1981 cagatttgga aaaaaggcta acaatgcgtt gcagcaccag tcgcttcgct ccttggacag
     2041 cttttaagtc gcgtctttgt ggttttgctg cgcaaaagta ttccacaaag ccgcaactta
     2101 aaagctgccg ctgaacttaa cgttaggcat catgggtgaa tttttccctg cacaagtttt
     2161 caagcagctg tcccacgctc gcgcggtgat cgagcgccat ctggctgcga cactggacac
     2221 aatccacctg ttcggatctg cgatcgatgg agggctgaag ccggacagcg acatagactt
     2281 gctcgtgacc gtcagcgccg cacctaacga ttcgctccgg caggcgctaa tgctcgattt
     2341 gctgaaagtc tcatcaccgc caggcgatgg cggaacatgg cgaccgctgg agctaactgt
     2401 tgtcgctcga agcgaagtag tgccttggcg ctatccggcg cggcgtgagc ttcagttcgg
     2461 tgagtggctc cgccacgaca tcctttccgg aacgttcgag cctgccgttc tggatcacga
     2521 tcttgcgatt ttgctgacca aggcgaggca acacagcctt gcgcttctag gcccatccgc
     2581 agccacgttt ttcgagccgg tgccgaagga gcatttctcc aaggcgcttt tcgacactat
     2641 tgcccagtgg aatgcagagt cggattggaa gggtgacgag cggaacgtcg ttcttgctct
     2701 tgctcgcatt tggtacagcg cttcaactgg tctcattgct cctaaggacg ttgctgccgc
     2761 atgggtatcg gagcgtttgc ctgccgagca tcggcccctc atctgcaagg cacgcgcggc
     2821 gtacctgggt agcgaggacg acgacctagc aatgcgcgtc gaagagacgg ccgcgttcgt
     2881 tcgatatgcc aaagcaacga ttgagagaat cttgcgttga gcggcatgtg cgaaaagtgc
     2941 atcgacccgc gccgagggca tctgatgcct aactcggcgt tcaagcggac gggctgcgcc
     3001 cgccgctcaa ctatgcgtta gatgcactaa gcacataatt gctcacagcc aaactatcag
     3061 gtcaagtctg cttttattat ttttaagcgt gcataataag ccctacacaa attgggagat
     3121 atatcatgaa aggctggctt tttcttgtta tcgcaatagt tggcgaagta atcgcaacat
     3181 ccgcattaaa atctagcgag ggctttacta agcttgcccc ttccgccgtt gtcataatcg
     3241 gttatggcat cgcattttat tttctttctc tggttctgaa atccatccct gtcggtgttg
     3301 cttatgcagt ctggtcggga ctcggcgtcg tcataattac agccattgcc tggttgcttc
     3361 atgggcaaaa gcttgatgcg tggggctttg taggtatggg gctcataatt gctgcctttt
     3421 tgctcgcccg atccccatcg tggaagtcgc tgcggaggcc gacgccatgg tgacggtgtt
     3481 cggcattctg aatctcaccg aggactcctt cttcgatgag agccggcggc tagaccccgc
     3541 cggcgctgtc accgcggcga tcgaaatgct gcgagtcgga tcagacgtcg tggatgtcgg
     3601 accggccgcc agccatccgg acgcgaggcc tgtatcgccg gccgatgaga tcagacgtat
     3661 tgcgccgctc ttagacgccc tgtccgatca gatgcaccgt gtttcaatcg acagcttcca
     3721 accggaaacc cagcgctatg cgctcaagcg cggcgtgggc tacctgaacg atatccaagg
     3781 atttcctgac cctgcgctct atcccgatat tgctgaggcg gactgcaggc tggtggttat
     3841 gcactcagcg cagcgggatg gcatcgccac ccgcaccggt caccttcgac ccgaagacgc
     3901 gctcgacgag attgtgcggt tcttcgaggc gcgggtttcc gccttgcgac ggagcggggt
     3961 cgctgccgac cggctcatcc tcgatccggg gatgggattt ttcttgagcc ccgcaccgga
     4021 aacatcgctg cacgtgctgt cgaaccttca aaagctgaag tcggcgttgg ggcttccgct
     4081 attggtctcg gtgtcgcgga aatccttctt gggcgccacc gttggccttc ctgtaaagga
     4141 tctgggtcca gcgagccttg cggcggaact tcacgcgatc ggcaatggcg ctgactacgt
     4201 ccgcacccac gcgcctggag atctgcgaag cgcaatcacc ttctcggaaa ccctcgcgaa
     4261 atttcgcagt cgcgacgcca gagaccgagg gttagatcat gcctagcatt caccttccgg
     4321 ccgcccgcta gcggaccctg gtcaggttcc gcgaaggtgg gcgcagacat gctgggctcg
     4381 tcaggatcaa actgcactat gaggcggcgg ttcataccgc gccaggggag cgaatggaca
     4441 gcgaggagcc tccgaacgtt cgggtcgcct gctcgggtga tatcgacgag gttgtgcggc
     4501 tgatgcacga cgctgcggcg tggatgtccg ccaagggaac gcccgcctgg gacgtcgcgc
     4561 ggatcgaccg gacattcgcg gagaccttcg tcctgagatc cgagctccta gggatcgcct
     4621 cagaaaacgg aaaataaagc acgctaagcc gtaagtaagc gtgctcctgt gaaagccaca
     4681 gctaaaactg cgtagtacac atagaggtat ttttttctag atttatatcg aatttcgtta
     4741 tcgaatttcg cttattattg atcaactcgt tgcagatcat gaaggcgaaa gtatgacgaa
     4801 taaccctacc gatgacagca gaccatggtc ggtctttctt atttttctgc ggcttggatt
     4861 gacatctttt ggcggcccca ttgcgcactt gggctacttc cgcgccgaat ttgtcacacg
     4921 gcggcgctgg ctctccgaac ggagctatgc tgacttggtc gcgctttgtc agttcttgcc
     4981 agggcctgca agcagccagg tcg
//
LOCUS       DAFGPF010000340         2825 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.238, whole genome shotgun sequence.
ACCESSION   DAFGPF010000340 DAFGPF010000000
VERSION     DAFGPF010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2825
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.238"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            167..1042
                     /locus_tag="LSX49_005286"
     CDS             167..1042
                     /locus_tag="LSX49_005286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-15"
                     /protein_id="HBL7171516.1"
                     /translation="MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQS
                     GGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKK
                     SDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGD
                     ETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNT
                     TGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESR
                     RDVLASAAKIVTDGL"
     gene            complement(1089..1421)
                     /locus_tag="LSX49_005287"
     CDS             complement(1089..1421)
                     /locus_tag="LSX49_005287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="HBL7171517.1"
                     /translation="MRPHRHPHTFELLLPLRGRFVVLNFDDRGTVTHRAILGETCTVL
                     EMAAGTWHAVLSLDTGGIIFEVKHGGYQPVAADDYAHWAPAEGEPGTTELMAWYAQAQ
                     VGDSTFAV"
     gene            1435..2787
                     /locus_tag="LSX49_005288"
                     /pseudo
     CDS             1435..2787
                     /locus_tag="LSX49_005288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
BASE COUNT          693 a          713 c          772 g          647 t
ORIGIN      
        1 tttatcaaaa atgattgaaa ggtggttgta aataatgtta caatgtgtga gaagcagtct
       61 aaattcttcg tgaaatagtg atttttgaag ctaataaaaa acacacgtgg aatttaggga
      121 ctattcatgt tgttgttatt tcgtatcttc cagaataagg aatcccatgg ttaaaaaatc
      181 actgcgccag ttcacgctga tggcgacggc aaccgtcacg ctgttgttag gaagtgtgcc
      241 gctgtatgcg caaacggcgg acgtacagca aaaacttgcc gaattagagc ggcagtcggg
      301 aggcagactg ggtgtggcat tgattaacac agcagataat tcgcaaatac tttatcgtgc
      361 tgatgagcgc tttgcgatgt gcagcaccag taaagtgatg gccgcggccg cggtgctgaa
      421 gaaaagtgaa agcgaaccga atctgttaaa tcagcgagtt gagatcaaaa aatctgacct
      481 tgttaactat aatccgattg cggaaaagca cgtcaatggg acgatgtcac tggctgagct
      541 tagcgcggcc gcgctacagt acagcgataa cgtggcgatg aataagctga ttgctcacgt
      601 tggcggcccg gctagcgtca ccgcgttcgc ccgacagctg ggagacgaaa cgttccgtct
      661 cgaccgtacc gagccgacgt taaacaccgc cattccgggc gatccgcgtg ataccacttc
      721 acctcgggca atggcgcaaa ctctgcggaa tctgacgctg ggtaaagcat tgggcgacag
      781 ccaacgggcg cagctggtga catggatgaa aggcaatacc accggtgcag cgagcattca
      841 ggctggactg cctgcttcct gggttgtggg ggataaaacc ggcagcggtg gctatggcac
      901 caccaacgat atcgcggtga tctggccaaa agatcgtgcg ccgctgattc tggtcactta
      961 cttcacccag cctcaaccta aggcagaaag ccgtcgcgat gtattagcgt cggcggctaa
     1021 aatcgtcacc gacggtttgt aatagcggaa acggaatggg gaaactcatt ccgtttttgt
     1081 ttatcgcctt agacggcaaa agtgctgtcg cccacctgcg cttgcgcata ccaggccata
     1141 agctccgtgg ttcctggttc tccttccgct ggagcccagt gcgcatagtc atcggcagcc
     1201 acgggttgat agccaccgtg ttttacttca aaaattatgc caccggtatc cagcgacagc
     1261 acggcatgcc aggttcctgc ggccatctcc agcaccgtac aggtttcccc caatatcgcc
     1321 cgatgggtga cggtaccccg atcgtcaaaa ttcagcacca cgaaacgacc ccttaatggc
     1381 aacagtagct cgaaggtgtg agggtgtcgg tgcgggcgca cgtaggtccc aggtcatatt
     1441 ccttccggcg tccggcattt taccgccaga cagctcggga ttcgtgatat caccgttctt
     1501 gcagaatacg gtcagaggga aaatacccgc cgtgagcatg cagcgctgat acgtcagcac
     1561 tatcagtatc gtgaatttgc ctggccctgg acatttcgcc ttacccgtct tttatatacc
     1621 cggagctgga taagcaacga acgtcctggc ctgcttttcg atctggcgac agggtggctt
     1681 atgcaacatc gtattattct ccccggagcc actacgctga cccggttgat ttcagaggta
     1741 agggaaaagg cgacgttgcg cctgtggaac aaactggcac tgataccgtc agccgaacag
     1801 cgttcacagc tggagatgct gctggggcca actgattgca gccgcctgtc tttactggaa
     1861 tcactgaaaa agggccctgt gaccatcagt ggtccggcgt ttaatgaagc aattgaacgc
     1921 tggaaaactc tgaacgattt tggcctgcat gctgaaaacc tgagtacact cccggctgtg
     1981 cgcctgaaaa atctcgcacg ttatgctggt atgacttcgg tgttcaatat tgccaggatg
     2041 tcaccgcaga aaaggatggc ggttctggtt gcctttgtcc ttgcatggga aacgctggcg
     2101 ctggatgatg cattggacgt tctggacgcc atgctggccg ttatcatccg tgacgccaga
     2161 aagattgggc agaaaaaacg gctccgctcg ctgaaggatc tggataaatc tgcattggcg
     2221 ctcgccagcg catgttcgta cctgctgaaa gaagaaacac cggacgaatc gattcgtgct
     2281 gaggtgttca gctacatccc aaggcaaaag ctggctgaaa tcatcacgct tgtccgtgaa
     2341 attgcccggc cctcagacga taattttcat gaagaaatgg tggagcagta cgggcgcgtt
     2401 cgtcgtttcc tgccccatct gctgaatacc gttaaatttt catccgcacc tgccggggtt
     2461 accactctga atgcctgtga ctacctcagc cgggagttca gctcacggcg gcagtttttt
     2521 gacgacgcac caacggaaat tatcagtcgg tcatggaaac ggctggtgat taacaaggaa
     2581 aaacatatca cccgcagggg atacacgctc tgctttctca gtaaactgca ggatagtctg
     2641 aggcggaggg atgtctacgt taccggcagt aaccggtggg gagatcctcg tgcaagatta
     2701 ctacagggtg ctgactggca ggcaaaccgg attaaggttt atcgttcttt ggggcacccg
     2761 acagacccgc aggaagcaat aaaatcggca ctgttgcaaa gttagcgatg aggcagcctt
     2821 ttgtc
//
LOCUS       DAFGPF010000341         2804 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.240, whole genome shotgun sequence.
ACCESSION   DAFGPF010000341 DAFGPF010000000
VERSION     DAFGPF010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2804
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.240"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..997
                     /locus_tag="LSX49_005289"
     CDS             <1..997
                     /locus_tag="LSX49_005289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBL7171518.1"
                     /translation="LQEHACDKINMVAENRGLTMAELEDRLAPDLGLDSSGSLTLDFG
                     PRQFTVGFDETLKPVVRDANGKVLKDLPKPNQSDDKTLATDAVNLFKQLKKDVRAIAS
                     QQIDRLEQAMCQRRRWTAEQFRLFLVEHPLVRHLTRRLLWGVYTEENTLIACFRVAED
                     STYSDAQDELFTLPAGNIGIPHVLEISPESAAAFGQIYTDYEQLPPFRQLDRGYYHLA
                     DNERDSHELIRWQGRLCQAGRIVGLERRGWQRLEESGSVYAMRKSTPYGDLELETEPF
                     SLIYGETGYGDQLPVESVKITSPDNRYGKQSSLTFSALDDITASELINDIESLFD"
     gene            1010..2041
                     /locus_tag="LSX49_005290"
                     /pseudo
     CDS             1010..2041
                     /locus_tag="LSX49_005290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000860751.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="WGR domain-containing protein"
     gene            2125..2679
                     /locus_tag="LSX49_005291"
     CDS             2125..2679
                     /locus_tag="LSX49_005291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /protein_id="HBL7171519.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGRWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPYGPAVYMVQTRQAFERTRSDA"
BASE COUNT          763 a          714 c          722 g          605 t
ORIGIN      
        1 attacaggaa catgcctgcg acaaaatcaa catggtcgct gaaaatcgcg ggctgactat
       61 ggctgaactg gaagaccgcc tggcaccgga tttaggactt gatagcagtg gctcgttgac
      121 actggatttc ggcccacgtc aatttaccgt tggttttgac gaaactttaa aacccgtggt
      181 tcgcgacgca aacggcaaag ttctgaaaga tttacccaaa ccaaatcaga gcgatgataa
      241 aacgctggca actgacgcgg ttaatctctt caaacagttg aaaaaagatg tacgcgccat
      301 agccagccag cagattgatc gtctggagca ggctatgtgc cagcgcagac gctggacggc
      361 agagcagttc cgcctgttcc tggtggagca tccgctggta cgtcacttaa cccgacggtt
      421 gttatggggg gtatatactg aggaaaacac gctgattgcc tgcttccggg tcgcagaaga
      481 cagcacttac agcgatgcgc aggatgagct atttacgttg ccagcaggaa acatcggtat
      541 tccgcatgtg ctggaaatat ctcctgaatc cgccgctgca tttgggcaaa tttatactga
      601 ttacgaacag cttcctccgt tccgccaact cgatcgtggt tattaccacc ttgctgataa
      661 tgaacgtgat tcccatgaat tgatacgctg gcaaggacgt ctttgccagg ccgggcgcat
      721 tgtcgggctg gaacgccgag gctggcaacg tctggaagaa agcggcagcg tttacgcgat
      781 gcgcaaatct actccttatg gcgatctcga acttgaaaca gaaccttttt cattaattta
      841 tggtgaaacg gggtatggcg accagctacc ggttgaaagc gtaaaaatca cctcgcctga
      901 taatcgctac ggtaaacaat cctcactcac tttttccgcg ctcgacgaca tcaccgccag
      961 cgaactcatt aacgacattg aatcactgtt tgattaaaag gatttagcaa tgaaaaccta
     1021 tatttatcag gacgaaaaat cacataaatt ctgggcagta gagcagcagg aaaatgaact
     1081 gcatatcagt tggggcaaag tcggcactaa cgggcaaagc cagataaaaa gctttgctga
     1141 tgcggcggcg gcggaaaaag cggagctgaa gttgattgcg gagaaaacga aaaagggcta
     1201 cgcagaagaa gtatccgtga cgacaccgac atctgccccc gtccaggtta tcgcatgctc
     1261 tgaaaaagcc cctttgccgc aagacaaacc accatttgct gaagaccacc ttccctggct
     1321 ggcagacgac gcccaaatca ttttaccgac agaggtcgca ccaaccacac taagtcatcg
     1381 acgctggcct ggcgattctg tgccacagga gaatgaatta actctgctac gctccgtcgc
     1441 cgcgcatact caccggcgtt ttaaaaaggt gatcaccttc gattacagca cctgttcact
     1501 ggactggcag caggcgatta cacaagcagt gggccttatc gactcaccga ttagcaccgc
     1561 actaccaccg atggttctgg cggtactggt tgcgctggaa caaggcttca atcgcaacga
     1621 tcacgaagag ttaatggatc aaattgtcca ggagggtggt ctggaatatg ccactgaggt
     1681 tgtcattgca ttgcaagcca tccgctttga ctggaattat gatgcccacc tcattacgtt
     1741 taccccggat aacaagcagc ctggctatct gtcacgcttt gcctcggttg aaatgcgtct
     1801 gcgtaaacat ctctcactag caaatgacga tgtatggcag cgctgcgccg acaaactgat
     1861 tgcagctctc ggaaacatac ccgcctggca tcagccgctg gttgcgttat tgttgccgga
     1921 aaaacaagat gtgagccatg agattgccag acgtctttgc ggacaaaaag ggttatatgc
     1981 gctggaatgg ctaaaactaa cggccgccga cgagcaggta ttggcagaac tggggaaata
     2041 cggcataata agccctacac aaattgggag ttagacatca tgagcaacgc aaaaacaaag
     2101 ttaggcatca caaagtacag catcgtgacc aacagcaacg attccgtcac actgcgcctc
     2161 atgactgagc atgaccttgc gatgctctat gagtggctaa atcgatctca tatcgtcgag
     2221 tggtggggcg gagaagaagc acgcccgaca cttgctgacg tacaggaaca gtacttgcca
     2281 agcgttttag cgcaagagtc cgtcactcca tacattgcaa tgctgaatgg agagccgatt
     2341 gggtatgccc agtcgtacgt tgctcttgga agcggggacg gacggtggga agaagaaacc
     2401 gatccaggag tacgcggaat agaccagtta ctggcgaatg catcacaact gggcaaaggc
     2461 ttgggaacca agctggttcg agctctggtt gagttgctgt tcaatgatcc cgaggtcacc
     2521 aagatccaaa cggacccgtc gccgagcaac ttgcgagcga tccgatgcta cgagaaagcg
     2581 gggtttgaga ggcaaggtac cgtaaccacc ccatatggtc cagccgtgta catggttcaa
     2641 acacgccagg cattcgagcg aacacgcagt gatgcctaac ccttccatcg agggggacgt
     2701 ccaagggctg gcgcccttgg ccgcccctca tgtcaaacgt tgggcgaacc cggagcctca
     2761 ttaattgtta gccgttaaaa ttaagccctt taccaaacca atac
//
LOCUS       DAFGPF010000342         1599 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.271, whole genome shotgun sequence.
ACCESSION   DAFGPF010000342 DAFGPF010000000
VERSION     DAFGPF010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1599
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.271"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            8..1141
                     /locus_tag="LSX49_005292"
     CDS             8..1141
                     /locus_tag="LSX49_005292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HBL7171520.1"
                     /translation="MFKTTLCTLLITASCSTFAAPQQINDIVHRTITPLIEQQRIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMKTRVFQPLKLNHTWINVPSAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKILQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDIIINGSDNKIALAARPVKPITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNTLQ"
     gene            1230..>1599
                     /gene="blc"
                     /locus_tag="LSX49_005293"
     CDS             1230..>1599
                     /gene="blc"
                     /locus_tag="LSX49_005293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HBL7171521.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDREMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDR"
BASE COUNT          420 a          410 c          387 g          382 t
ORIGIN      
        1 agaccctatg ttcaaaacga cgctctgcac cttattaatt accgcctctt gctccacatt
       61 tgccgcccct caacaaatca acgatattgt gcatcgcaca attaccccgc ttatagagca
      121 acaaaggatc cccggtatgg cggtagcggt aatttatcag ggtaaacctt attactttac
      181 ctggggctat gcggacatcg ccaaaaagca gcccgtcaca cagcaaacgt tgtttgagtt
      241 aggttcggtc agcaaaacat ttacgggcgt gcttggtggc gacgctattg ctcgagggga
      301 aatcaagtta agcgatccca caacaaaata ctggcctgaa cttaccgcta aacagtggaa
      361 tgggatcaca ctattacatc tcgcaaccta caccgctggc ggcctgccat tgcaggtgcc
      421 ggatgaggtg aaatcctcaa gcgacttgct gcgcttctat caaaactggc agcctgcatg
      481 ggctccagga acacaacgtc tgtatgccaa ctccagtatc ggtttgttcg gcgcactggc
      541 tgtgaagccg tctggtttga gttttgagca ggcgatgaaa actcgtgtct tccagccact
      601 caaactcaat catacgtgga ttaatgtacc gtccgcagaa gaaaagaact acgcctgggg
      661 atatcgcgaa ggtaaggcag tacatgtttc gccaggggcg ttagatgctg aagcttatgg
      721 tgtgaagtcg accattgaag atatggcccg ctgggtgcaa agcaatttaa aaccccttga
      781 tatcaatgag aaaatacttc aacaagggat acaactggca caatctcgct actggcaaac
      841 cggcgatatg tatcagggtc tgggctggga aatgctggac tggccggtaa atcctgacat
      901 catcattaac ggcagtgaca ataaaattgc actggcagca cgccccgtaa aaccgattac
      961 gcccccaact cctgcagtac gcgcatcatg ggtacataaa acgggggcga ccggcggatt
     1021 tggtagctat gtcgcgttta ttccagaaaa agagctgggt atcgtgatgc tggctaacaa
     1081 aaactatccc aatccagcga gagttaccgc cgcctggcag attctcaaca ctctacagta
     1141 aaatttcatc gggtccgaat tttcggacct tttctccgct tttccttgct gtcatctaca
     1201 cttagaaaaa aaccagtaag gaaacattta tgcgcctgct ccctctcgtt gccgcagcga
     1261 cagctgcatt tctggtcgtt gcctgcagtt ctcctacacc gccgcgtggc gtgaccgtag
     1321 tgaataattt cgacgctaaa cgctatctcg gcacctggta tgagattgcc cgttttgatc
     1381 accgctttga acgtggactg gaaaaagtca ccgcaacata cagcctgcgt gatgacggcg
     1441 gcctgaatgt cattaataaa ggctataacc ctgacagaga aatgtggcag cagagtgaag
     1501 ggaaagcgta ctttaccggc gcaccaactc gcgctgcgct gaaagtgtca ttctttggtc
     1561 ctttctatgg cggttataac gttattgcac tcgatcggg
//
LOCUS       DAFGPF010000343         1389 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.278, whole genome shotgun sequence.
ACCESSION   DAFGPF010000343 DAFGPF010000000
VERSION     DAFGPF010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.278"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            83..943
                     /gene="aac(3)-IIe"
                     /locus_tag="LSX49_005294"
     CDS             83..943
                     /gene="aac(3)-IIe"
                     /locus_tag="LSX49_005294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(3)-IIe"
                     /protein_id="HBL7171522.1"
                     /translation="MHTRKAITEAIRKLGVQTGDLLMVHASLKAIGPVEGGAETVVAA
                     LRSAVGPTGTVMGYASWDRSPYEETLNGARLDDKARRTWPPFDPATAGTYRGFGLLNQ
                     FLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLG
                     APLNSVTALHYAEAVADIPNKRWVTYEMPMLGRNGEVAWKTASEYDSNGILDCFAIEG
                     KPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGATPIVPAHE
                     AAQRSCEPSG"
     gene            956..>1389
                     /locus_tag="LSX49_005295"
     CDS             956..>1389
                     /locus_tag="LSX49_005295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL7171523.1"
                     /translation="MIIWINGPFGAGKTTLAERLRDRRPKSLIFDPEEIGFVVKETVP
                     IPASGDYQDLPLWRGLTIAAVSEIRRNYSQDIIIPMTLVHPDYLTEILDGLRQIDDQL
                     LHIFLMLNEDLLRHRISNQTMHPDPNRNAEIREWRLANVARC"
BASE COUNT          304 a          377 c          417 g          291 t
ORIGIN      
        1 atgataagtt tatcaccacc gactatttgc aacagtgcct ctcgataggt atagtgtttt
       61 gcagtttaga ggagatatcg cgatgcatac gcggaaggca ataacggagg caattcgaaa
      121 attaggagtc caaaccggtg acctgttgat ggtgcatgcc tcacttaaag cgattggtcc
      181 ggtcgaagga ggagcggaga cggtcgttgc cgcgttacgc tccgcggttg ggccgactgg
      241 cactgtgatg ggatacgcgt cgtgggaccg atcaccctac gaggagactc tgaatggcgc
      301 tcggttggat gacaaagccc gccgtacctg gccgccgttc gatcccgcaa cggccgggac
      361 ttaccgtggg ttcggcctgc tgaatcaatt tctggttcaa gcccccggcg cgcggcgcag
      421 cgcgcacccc gatgcatcga tggtcgcggt tggtccgcta gctgaaacgc tgacggagcc
      481 tcacgaactc ggtcacgcct tgggggaagg gtcgcccgtc gagcggttcg tccgccttgg
      541 cgggaaggcc ctgctgttgg gtgcgccgct aaactccgtt accgcattgc actacgccga
      601 ggcggttgcg gatatcccca acaaacgatg ggtgacgtat gagatgccga tgcttggaag
      661 aaacggtgaa gtcgcctgga aaacggcatc agaatacgat tcaaacggca ttctcgattg
      721 ctttgctatc gaaggaaagc cggatgcggt cgaaactata gcaaatgctt acgtgaagct
      781 cggtcgccat cgagaaggtg tcgtgggctt tgctcagtgc tacctgttcg acgcgcagga
      841 catcgtgacg ttcggcgtca cctatcttga gaagcacttc ggagccactc cgatcgtgcc
      901 agcacacgaa gccgcccagc gctcttgcga gccttccggt tagaggccgt cgacaatgat
      961 aatctggatc aacggacctt tcggcgccgg aaagacgact ctcgctgagc ggctgcgcga
     1021 tcggcgtccg aaatcgctga tctttgaccc tgaggaaatc gggttcgtgg tgaaagaaac
     1081 ggtccccata ccagcgagcg gagactatca ggatctcccc ttgtggaggg gacttacgat
     1141 cgctgcggtc agcgagattc gcaggaatta ctcgcaggac atcatcatcc caatgacgct
     1201 cgtgcacccg gactatctga ctgagatact cgacgggtta aggcagatcg acgatcagct
     1261 gctgcacatc tttctgatgc ttaacgagga cctattgcgt caccggatct cgaaccagac
     1321 catgcatcct gacccgaatc ggaatgcgga gattcgagag tggcgattag cgaatgtcgc
     1381 ccgatgctt
//
LOCUS       DAFGPF010000344         1356 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.280, whole genome shotgun sequence.
ACCESSION   DAFGPF010000344 DAFGPF010000000
VERSION     DAFGPF010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1356
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.280"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            <1..738
                     /gene="blaOXA"
                     /locus_tag="LSX49_005296"
     CDS             <1..738
                     /gene="blaOXA"
                     /locus_tag="LSX49_005296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class D beta-lactamase"
                     /protein_id="HBL7171524.1"
                     /translation="VASPLFEGTEGCFLLYDASTNAEIAQFNKAKCATQMAPDSTFKI
                     ALSLMAFDAEIIDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVVWVSQEITQKIGLN
                     KIKNYLKDFDYGNQDFSGDKERNNGLTEAWLESSLKISPEEQIQFLRKIINHNLPVKN
                     SAIENTIENMYLQDLDNSTKLYGKTGAGFTANRTLQNGWFEGFIISKSGHKYVFVSAL
                     TGNLGSNLTSSIKAKKNAITILNTLNL"
     gene            876..>1356
                     /locus_tag="LSX49_005297"
     CDS             876..>1356
                     /locus_tag="LSX49_005297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBL7171525.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVGHCCKVSDEAAFC
                     "
BASE COUNT          439 a          283 c          289 g          345 t
ORIGIN      
        1 gttgcatctc cattatttga aggaactgaa ggttgttttt tactttacga tgcatccaca
       61 aacgctgaaa ttgctcaatt caataaagca aagtgtgcaa cgcaaatggc accagattca
      121 actttcaaga tcgcattatc acttatggca tttgatgcgg aaataataga tcagaaaacc
      181 atattcaaat gggataaaac ccccaaagga atggagatct ggaacagcaa tcatacacca
      241 aagacgtgga tgcaattttc tgttgtttgg gtttcgcaag aaataaccca aaaaattgga
      301 ttaaataaaa tcaagaatta tctcaaagat tttgattatg gaaatcaaga cttctctgga
      361 gataaagaaa gaaacaacgg attaacagaa gcatggctcg aaagtagctt aaaaatttca
      421 ccagaagaac aaattcaatt cctgcgtaaa attattaatc acaatctccc agttaaaaac
      481 tcagccatag aaaacaccat agagaacatg tatctacaag atctggataa tagtacaaaa
      541 ctgtatggga aaactggtgc aggattcaca gcaaatagaa ccttacaaaa cggatggttt
      601 gaagggttta ttataagcaa atcaggacat aaatatgttt ttgtgtccgc acttacagga
      661 aacttggggt cgaatttaac atcaagcata aaagccaaga aaaatgcgat caccattcta
      721 aacacactaa atttataaaa aatctaatgg caaaatcgcc caacccttca atcaagtcgg
      781 gacggccaaa agcaagcttt tggctcccct cgctggcgct cggcgcccct tatttcaaac
      841 gttagacggc aaagtcacag accgcgggat ctcttatgac caactacttt gatagcccct
      901 tcaaaggcaa gctgctttct gagcaagtga agaaccccaa tatcaaagtt gggcggtaca
      961 gctattactc tggctactat catgggcact cattcgatga ctgcgcacgg tatctgtttc
     1021 cggaccgtga tgacgttgat aagttgatca tcggtagttt ctgctctatc gggagtgggg
     1081 cttcctttat catggctggc aatcaggggc atcggtacga ctgggcatca tctttcccgt
     1141 tcttttatat gcaggaagaa cctgcattct caagcgcact cgatgccttc caaaaagcag
     1201 gtaatactgt cattggcaat gacgtttgga tcggctctga ggcaatggtc atgcccggaa
     1261 tcaagatcgg gcacggtgcg gtgataggca gccgctcgtt ggtgacaaaa gatgtggggc
     1321 actgttgcaa agttagcgat gaggcagcct tttgtc
//
LOCUS       DAFGPF010000345         1248 bp    DNA     linear   BCT 06-DEC-2021
DEFINITION  TPA_asm: Escherichia coli isolate econeo_2
            SAMEA8719913-rid13519973.guided.285, whole genome shotgun sequence.
ACCESSION   DAFGPF010000345 DAFGPF010000000
VERSION     DAFGPF010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8719913
            Sequence Read Archive: ERR5903277
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001196878.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001196878.1
            Genome Coverage       :: 54x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/06/2021 21:11:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,299
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,050
            CDSs (with protein)               :: 5,050
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 73 of 173
            Pseudo Genes (incomplete)         :: 110 of 173
            Pseudo Genes (internal stop)      :: 39 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8719913-rid13519973.guided.285"
                     /isolate="econeo_2"
                     /isolation_source="Human Sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="United Kingdom"
                     /collection_date="2015-03-15"
     gene            109..1014
                     /locus_tag="LSX49_005298"
     CDS             109..1014
                     /locus_tag="LSX49_005298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HBL7171526.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
     gene            1011..>1248
                     /locus_tag="LSX49_005299"
     CDS             1011..>1248
                     /locus_tag="LSX49_005299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL7171527.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWA
                     GATAASSVIATIIGAWVGGGLVDRFGRAPVALISG"
BASE COUNT          208 a          402 c          403 g          235 t
ORIGIN      
        1 gacaaaaggc tgcctcatcg ctaactttgc aacagtgccg gattgaatat aaccgacgtg
       61 actgttacat ttaggtggct aaacccgtca agccctcagg agtgaatcat gaccgtagtc
      121 acgaccgccg atacctccca actgtacgca cttgcagccc gacatgggct caagctccat
      181 ggcccgctga ctgtcaatga gcttgggctc gactatagga tcgtgatcgc caccgtcgac
      241 gatggacgtc ggtgggtgct gcgcatcccg cgccgagccg aggtaagcgc gaaggtcgaa
      301 ccagaggcgc gggtgctggc aatgctcaag aatcgcctgc cgttcgcggt gccggactgg
      361 cgcgtggcca acgccgagct cgttgcctat cccatgctcg aagactcgac tgcgatggtc
      421 atccagcctg gttcgtccac gcccgactgg gtcgtgccgc aggactcgga ggtcttcgcg
      481 gagagcttcg cgaccgcgct cgccgccctg catgccgtcc ccatttccgc cgccgtggat
      541 gcggggatgc tcatccgtac accgacgcag gcccgtcaga aggtggccga cgacgttgac
      601 cgcgtccgac gcgagttcgt ggtgaacgac aagcgcctcc accggtggca gcgctggctc
      661 gacgacgatt cgtcgtggcc agatttctcc gtggtggtgc atggcgatct ctacgtgggc
      721 catgtgctca tcgacaacac ggagcgcgtc agcgggatga tcgactggag cgaggcccgc
      781 gttgatgacc ctgccatcga catggccgcg caccttatgg tctttggtga agaggggctc
      841 gcgaagctcc tcctcacgta tgaagcggcc ggtggccggg tgtggccgcg gctcgcccac
      901 cacatcgcgg agcgccttgc gttcggggcg gtcacctacg cactcttcgc cctcgactcg
      961 ggtaacgaag agtacctcgc tgcggcgaag gcgcagctcg ccgcagcgga atgagcgaac
     1021 gtcgatatag cccgctcgcg acgctgttcg cggcgacctt tctcttccgg atcggcaacg
     1081 cggtggcggc cctcgcgctt ccatggttcg tcctgtctca tacaaagagc gcggcctggg
     1141 cgggcgccac ggccgctagc agcgtcatcg cgaccatcat cggcgcgtgg gttggtggtg
     1201 gcctcgtcga tcggttcggg cgcgcgcccg tcgcattgat ctcgggtg
//
